Altered Intercellular Communication

The table below contains sentences from PubMed articles, which describe the contribution of altered intercellular communication in the development, or disordered physiology of, a disease.
The sentences are derived from predictions after applying a supervised machine learning approach.
The columns represent the matched concept from the UMLS Metathesaurus, the matched aging hallmark, the sentence and the PubMed identifier.
There are hyperlinks to the associated PubMed article.
To view sentences for different aging hallmarks, navigate from the drop-down list on the left.

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Matched Disease Name	Matched Aging Hallmark	Sentence	PMID
Inflammation	Altered Intercellular Communication	Resolved sites had minimal histologic evidence of chronic inflammation and IL-6 accumulation; unresolved sites contained a substantial number of chronic inflammatory cells and IL-6 was widely distributed.	7473008
Gastritis	Altered Intercellular Communication	H. pylori strains possessing cagA have been associated with enhanced induction of acute gastric inflammation.	7473834
Inflammation, Fibrosis Assessment, Gangrene, Necrosis	Altered Intercellular Communication	Acute inflammation, free of fibrosis, with isolated foci of gangrene and necrosis of the bladder wall are histologically documented.	7474735
Retinal Detachment, Inflammation	Altered Intercellular Communication	The retinal detachment surgery was performed with the use of SF6 gas, which is known as a factor for increasing inflammation.	7474789
Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation seems to play an important role.	7474789
Inflammation, Treponemal Infections	Altered Intercellular Communication	The small ring-like enhancement was probably caused by inflammation associated with treponemal infection.	7477692
Lesion, Demyelination, Inflammation	Altered Intercellular Communication	Histological examination revealed that the cord lesion was acute demyelination with perivascular inflammation.	7477708
Communicable Diseases, Inflammation, Neoplasms	Altered Intercellular Communication	There was no evidence of inflammation, infection, or metastatic neoplasia.	7477972
Communicable Diseases, Inflammation	Altered Intercellular Communication	Imaging infection and inflammation in an African environment: comparison of 99Tcm-HMPAO-labelled leukocytes and 67Ga-citrate.	7478399
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	[Chronic inflammation of the gastric mucosa and some immunologic aspects of Helicobacter pylori infection].	7479229
Granulomatous inflammation	Altered Intercellular Communication	Histologically, a granulomatous inflammation was present, in which acid-fast bacilli could not be detected.	7479611
Inflammation	Altered Intercellular Communication	Epididymal PSV ratios > or = 1.7 or testicular ratios > or = 1.9 were diagnostic of acute inflammation (P < .0001).	7480687
Refractory anemias, Inflammation, Rheumatoid Arthritis, Neutrophil Infiltration	Altered Intercellular Communication	Neutrophil infiltration in synovial fluid is an important step in inflammation characterizing rheumatoid arthritis (RA).	7481076
Inflammation, Traumatic injury	Altered Intercellular Communication	Further research should focus on the interrelationship between pre-existing preoperative inflammation and the additional trauma inflicted by surgery in patients with severe injuries.	7481829
Headache, Cerebrovascular accident	Altered Intercellular Communication	Amino acid neurotransmitters play a role in the pathophysiology of headache that occurs at the onset of stroke.	7482645
Inflammation, Hemorrhage, Anastomotic Leak, Hematoma	Altered Intercellular Communication	Postoperative complications were seen in 10 patients, one of whom died (secondary haemorrhage 2; anastomotic leakage 1, Douglas haematoma 1, inflammation of the drainage tract 6).	7483869
Hashimotos encephalitis	Altered Intercellular Communication	On the basis of these findings, thyrotropin-releasing hormone may have an important role in Hashimoto's encephalopathy.	7485224
Communicable Diseases, Inflammation, Ischemic	Altered Intercellular Communication	The blinded scoring of lesions (including acute ascending infection, uteroplacental vascular pathologic processes and related ischemic damage, chronic inflammation, and coagulation related lesions) was analyzed by contingency tables (p < 0.05 significant).	7485294
Granulomatosis with polyangiitis	Altered Intercellular Communication	Neuro-ophthalmic manifestations of meningocerebral inflammation from the limited form of Wegener's granulomatosis.	7485363
Inflammation, Granulomatosis with polyangiitis	Altered Intercellular Communication	In all patients, results of a biopsy demonstrated necrotizing granulomatous inflammation consistent with Wegener's granulomatosis.	7485363
Inflammation	Altered Intercellular Communication	Extensive meningocerebral inflammation can occur before systemic involvement or laboratory confirmation.	7485363
Inflammation, Trypanosomiasis, Zebrafish	Altered Intercellular Communication	These data show that the levels of TNF-alpha in serum of T. b. gambiense-infected patients were correlated with disease severity (presence of signs of inflammation or presence of major neurologic signs) and indicate that TNF-alpha could be involved in some aspects of human African trypanosomiasis physiopathology.	7485714
Inflammation	Altered Intercellular Communication	Cardiopulmonary bypass (CPB) may be associated with the risk of a "whole body inflammation."	7486093
Hepatic inflammation, Necrosis	Altered Intercellular Communication	Liver biopsy specimens showed a decrease in hepatic inflammation and necrosis among ribavirin-treated patients whose aminotransferase levels became normal.	7486483
Inflammation	Altered Intercellular Communication	The decrease of NAG enzymuria was correlated with biochemical indices of inflammation like ESR or hemoglobin.	7487376
Cerebral Small Vessel Diseases, vascular inflammations	Altered Intercellular Communication	Small vessel disease was seen in all 10 patients who underwent biopsy, with perivascular or vascular inflammation seen in seven patients.	7487556
vascular inflammations	Altered Intercellular Communication	Onion bulbs were seen in all four patients who underwent biopsy, but no vascular inflammation or occlusion was seen.	7487556
Inflammation, Endophthalmitis	Altered Intercellular Communication	Little chronic inflammation and no signs of sympathetic ophthalmia were present.	7487608
Inflammation	Altered Intercellular Communication	Patients treated with systemic or periocular corticosteroids not accompanied by antiparasitic medication showed a rapid increase of inflammation.	7487620
Lymphocyte count decreased, Inflammation, Arthritis, Psoriatic	Altered Intercellular Communication	To determine if weekly oral 2-chlorodeoxyadenosine (2-CdA) can induce selective lymphocytopenia, and reduce inflammation, in patients with refractory psoriatic arthritis.	7488281
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To develop a method for quantifying acute synovial inflammation in rheumatoid arthritis (RA), utilizing magnetic resonance imaging (MRI).	7488282
Refractory anemias, Inflammation	Altered Intercellular Communication	Dynamic MRI is a valuable technique for assessing acute synovial inflammation in RA.	7488282
Communicable Diseases, Inflammation	Altered Intercellular Communication	Avidin is a protein which accumulates nonspecifically at sites of inflammation or infection.	7489208
Granuloma, Inflammation, Fatty degeneration, Siderosis	Altered Intercellular Communication	Forty-four percent of biopsies contained more than one histological abnormality including granulomas, inflammation, steatosis or siderosis.	7489625
Inflammatory Bowel Diseases, Inflammatory disease of mucous membrane	Altered Intercellular Communication	It is suppressed by butyrate and increased in inflammatory bowel disease independently of the presence of mucosal inflammation.	7489942
Inflammation, Specimen Source Codes - Abscess	Altered Intercellular Communication	Bowel inflammation was easily distinguished from abscess on serial images.	7489945
Inflammation, Anaphylactoid	Altered Intercellular Communication	Local activation of the complement cascade by glomerular IgA deposits and release of anaphylactoid factor are considered to be major triggers of inflammation, but clear-cut correlations between the severity of the histological findings and the intensity of glomerular deposition of immunoglobulin and complement fractions are still lacking.	7490687
Pneumonia, Lipid, Pneumonitis	Altered Intercellular Communication	The underlying cause of the condition was ingestion of animal fat in infancy, with a history of ghee oil aspiration which caused a chronic lung inflammation, lipoid pneumonia, proven by lung biopsy.	7491210
Asthma, Eosinophilic inflammation	Altered Intercellular Communication	Symptoms of mildly uncontrolled asthma are not always associated with eosinophilic airways inflammation as measured by sputum analysis.	7491553
Inflammation, Chronic lung disease, Respiratory Distress Syndrome, Newborn, Neutrophilia (finding)	Altered Intercellular Communication	Pulmonary neutrophilia characterises both the relatively transient inflammation associated with infant respiratory distress syndrome (IRDS) and the persistent inflammation of chronic lung disease.	7491556
Inflammation, Chronic lung disease	Altered Intercellular Communication	The possibility that persistently raised markers of inflammation indicate the development of chronic lung disease in low birth weight (< 1730 g) preterm (< 31 weeks) infants was therefore investigated.	7491556
Inflammation, Asthma, Bronchoconstriction	Altered Intercellular Communication	This persistent increase in plasma LTB4 and urinary LTE4 concentrations one month after a severe asthmatic episode suggests leukotriene production is related to chronic inflammation rather than to acute bronchoconstriction.	7492159
Inflammation, Joints	Altered Intercellular Communication	Th1 activation is a possible mechanism by which inflammation in RA joints is enhanced.	7492224
Inflammation, Joints, Cartilage damage	Altered Intercellular Communication	The Th2 cytokine IL-4 inhibits this Th1 activity and may diminish inflammation and induction of cartilage damage in RA joints.	7492224
Interstitial inflammation	Altered Intercellular Communication	In spite of the low number of patients investigated, it is tempting to speculate that elderly patients with a disease onset around 60 years tend to be the candidates in whom a positive gallium-67 scintigraphy test may best indicate a silent myocardial interstitial inflammation.	7492229
Fibrosis Assessment, Glaucoma, CTCAE, Conjunctivitis	Altered Intercellular Communication	On biopsy material, differences in the degree of conjunctival inflammation and fibrosis between topically treated glaucoma patients and age matched controls, were examined histologically.	7493236
Hepatic inflammation	Altered Intercellular Communication	Follow-up liver biopsy showed reduced hepatic inflammation in 80% of treated patients and in 29% of controls (P < 0.001).	7493300
Inflammation	Altered Intercellular Communication	CD may be localized or multifocal, and is often associated with signs and symptoms of generalized inflammation.	7494511
Inflammation, Microcytic hypochromic anemia (disorder), Hypergammaglobulinemia, Angiolymphoid hyperplasia	Altered Intercellular Communication	We describe a 9-year-old boy who developed Castleman's disease with systemic findings of hypochromic microcytic anemia, growth arrest, inflammation, and hyperimmunoglobulinemia.	7494511
Inflammation, Angiolymphoid hyperplasia	Altered Intercellular Communication	Because these cytokines are mediators of immune regulation and inflammation, we propose that TNF-beta and gamma-IFN also play an important role in the pathophysiology of Castleman's disease.	7494511
Anorexia Nervosa, Hyponatremia, Inappropriate ADH Syndrome	Altered Intercellular Communication	[Severe hyponatremia associated with anorexia nervosa: role of inappropriate antidiuretic hormone secretion?].	7496476
Intraocular inflammation, Necrosis of retina	Altered Intercellular Communication	Examination shows an intraocular inflammation with retinal necrosis in temporal periphery.	7496577
Inflammation, Chronic inflammation	Altered Intercellular Communication	Segmental and total scintigraphy scores correlated most strongly with histological grades for acute inflammation (r = 0.75, p < 0.001 and r = 0.9, p < 0.001, respectively) and chronic inflammatory cell infiltration in the lamina propria (r = 0.76, p < 0.001 and r = 0.86, p < 0.001, respectively).	7496705
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	99Tcm-HMPAO leucocyte scintigraphy detected acute inflammation in the colon of patients with ulcerative colitis with a sensitivity of 91% and negative predictive value of 80% and localized acute inflammation to a particular colonic segment with a sensitivity of 82%, specificity of 94%, accuracy of 88%, positive predictive value of 94% and negative predictive value of 91%.	7496705
Inflammation, Acute inflammation	Altered Intercellular Communication	99Tcm-HMPAO leucocyte scintigraphy positivity predicts and localizes colonic acute inflammation with a high degree of confidence, but negative scintigraphy does not exclude acute inflammation.	7496705
Crohn Disease, Inflammation	Altered Intercellular Communication	The high immunoreactivity of 1F10 antigen in the muscularis propria in Crohn's disease indicates a state of tropical immunological activation and may be important in the maintenance of chronic inflammation by facilitating leukocyte migration into sites of Crohn's disease involvement.	7496869
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) has been hypothesized to be an inflammatory condition.	7496909
Hepatic inflammation	Altered Intercellular Communication	For some HIV-positive children with HIV-induced hepatitis, AZT may be the drug of choice to resolve hepatic inflammation caused by this virus.	7496978
Inflammation	Altered Intercellular Communication	Apicectomy is offered where routine endodontics cannot resolve periapical inflammation.	7498042
Inflammation, Chronic superficial gastritis	Altered Intercellular Communication	42/49 cases (85.7%) with chronic superficial gastritis showed non-active quiescent chronic inflammation.	7498044
Inflammation, Asthma	Altered Intercellular Communication	Eosinophilic inflammation is associated with elevation of interleukin-5 in the airways of patients with spontaneous symptomatic asthma.	7499683
Inflammation, Asthma	Altered Intercellular Communication	Because eosinophilic inflammation is an important component of symptomatic episodes of asthma, we have investigated whether increased levels of IL-5 protein are present in bronchoalveolar lavage (BAL) fluid of patients with spontaneously symptomatic asthma (FEV1, l61% predicted; FEF25%-75%, 30% predicted) compared with patients with asymptomatic asthma (FEV1, 88% predicted; FEF25%-l75%, 76% predicted).	7499683
Infarction, Inflammation	Altered Intercellular Communication	In four cases, vascular CNS infarcts with inflammation were compared with MS plaques from the same brain.	7500044
Cecal Diverticulum, Appendicitis, CTCAE, Perforation (observation)	Altered Intercellular Communication	Inflammation of perforation of a cecal diverticulum is an uncommon condition that mimics acute appendicitis.	7500801
Inflammation	Altered Intercellular Communication	Because of the severe inflammation, ileocecal resection or right hemicolectomy was necessary; in one case we performed a local excision.	7500801
Inflammation, Axonal loss	Altered Intercellular Communication	At autopsy the spinal cord showed widespread demyelination, axonal loss, and chronic inflammation.	7501151
Inflammation, Specimen Type - Fistula	Altered Intercellular Communication	The anatomic basic of the syndrome (an anomalous relationship between the cystic duct and the common hepatic duct) when associated with inflammation and interbiliary fistula predisposes to a critical situation to be clearly detected and contributes to technical difficulties when surgical management is performed.	7501210
Icterus, Inflammation	Altered Intercellular Communication	The laparoscopic surgery has not yet entered as the first-choice procedure for this syndrome due to jaundice and acute inflammation considered by some as contraindication to mini-invasive treatment.	7501210
Inflammation, Virus Diseases, Acquired Immunodeficiency Syndrome	Altered Intercellular Communication	Because the inner ear viral infections were asymptomatic and there was an absence of pathologic damage and inflammation, we suggest that some viral inner ear infections in patients with AIDS are nonpathogenic and elicit no inflammation or that the viral infections occur terminally and elicit no inflammation because of immunosuppression from the AIDS.	7501379
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Teeth extracted 30 days afer ETD showed varied responses, ranging from complete recovery in some cases to persistence of inflammation and pulpal fibrosis.	7503040
Helicobacter heilmannii, Gastritis	Altered Intercellular Communication	Helicobacter heilmannii appears to be a significant though uncommon cause of gastric inflammation.	7503664
Inflammation, Thrombosis, Vasculitis, CTCAE	Altered Intercellular Communication	Activation of the vascular endothelium is thought to be an important facet of inflammation, thrombosis, and vasculitis.	7506877
Nasal Polyps	Altered Intercellular Communication	Nasal polyposis is a chronic inflammatory condition of the upper airways characterized by infiltration of activated inflammatory cells, including mast cells, both in the epithelium and in the stroma.	7508349
Inflammation, Primary malignant neoplasm, prostatitis	Altered Intercellular Communication	Patients with inflammation (prostatitis) present in their biopsy specimens have serum PSA levels and PSAD values intermediate between those with benign tissue (without inflammation) and cancer.	7509526
Inflammation, Atrophic	Altered Intercellular Communication	Influence of inflammation and atrophy on pancreatic secretory trypsin inhibitor levels within the gastric mucosa.	7509764
Alzheimers Disease", Cognition Disorders	Altered Intercellular Communication	Because galanin inhibits cholinergic neurotransmission, these findings may have important implications in the understanding of Alzheimer's disease neuropathology and associated cognitive deficits.	7510783
Inflammation, Atherosclerosis	Altered Intercellular Communication	It is defined as the triad of advanced atherosclerosis, medical thinning and aortic adventitial chronic inflammation.	7511559
Inflammation, Atheroma	Altered Intercellular Communication	A consistent finding was the presence of E-selectin on endothelial cells in up to 50% of the vessels throughout the aortic wall and at the base of the atheroma, independent of the severity of inflammation.	7511559
Inflammation	Altered Intercellular Communication	ICAM-1 expression was abundant on many cell types and increased with the severity of chronic inflammation, being strongest in the germinal centres.	7511559
Inflammation, Atherosclerosis	Altered Intercellular Communication	The pattern of expression of the adhesion molecules suggests a role in the initiation and progression of chronic inflammation associated with advanced atherosclerosis.	7511559
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	However, little is yet known about the in vivo expression of G-CSF as a mediator in inflammation and malignancy within the human central nervous system.	7513314
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	The authors suggest that tissue macrophages may play a regulatory role in fibrin accumulation in association with autoimmune inflammation and consequently in demarcation of the inflamed tissue.	7514111
Refractory anemias, Inflammation	Altered Intercellular Communication	IGFBP-3 was not affected by PTH infusion in patients with RA when the disease had high activity, but when inflammation had subsided they responded with a similar increase in IGFBP-3 as the control group and basal IGF-I and -II levels were normalised.	7514466
Inflammation	Altered Intercellular Communication	Inflammation may inhibit bone formation via decreased serum levels of IGFs and blocked IGFBP-3 response to PTH.	7514466
Inflammation, Hepatitis C, Hepatitis, Chronic	Altered Intercellular Communication	Our findings suggest that Fas antigen expression (apoptosis) plays an important role in inflammation in the hepatitis C virus-infected liver, particularly in the active inflammation of chronic hepatitis C.	7514559
Nasal Polyps, allergic inflammation	Altered Intercellular Communication	The importance of P-selectin in eosinophil adhesion to nasal polyp endothelium suggests that P-selectin antagonists may be effective at inhibiting eosinophil accumulation at sites of allergic inflammation.	7516413
Neurogenic Inflammation, Cutaneous hyperalgesia	Altered Intercellular Communication	Substance P is involved in the generation of neurogenic inflammation and causes cutaneous hyperalgesia.	7518480
Inflammation, prostatitis	Altered Intercellular Communication	Histological prostatitis was divided into three groups: acute, chronic-active, and chronic-inactive inflammation.	7518599
Refractory anemias, Inflammation, Disease	Altered Intercellular Communication	Serum KS was reduced in both diseases and in RA was inversely related to both systemic and joint inflammation markers.	7518830
Diabetes Mellitus, Insulin-Dependent, Stiff-Person Syndrome	Altered Intercellular Communication	Thus, destruction of pancreatic beta cells, which results in insulin-dependent diabetes mellitus (IDDM), and impairment of GABA-ergic synaptic transmission in Stiff-Man syndrome (SMS) are both characterized by circulating autoantibodies to GAD65.	7519242
Pituitary Adenoma	Altered Intercellular Communication	The widespread pituitary adenoma expression of SSTR3, regardless of hormonal secretory type, suggests that SSTR3 might be involved in a somatostatin action(s) other than GH or TSH regulation.	7521350
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	These results suggest that the changes in VIP- and SP-nerve distributions in the mucosa with IBD are subsequent to mucosal inflammation and damage.	7524953
Immunoglobulin A deficiency (disorder)	Altered Intercellular Communication	IgA deficiency associated with growth hormone deficiency in a boy with short arm deletion of chromosome 18 (46,XY,18p-).	7527197
Inflammation, Adenoma	Altered Intercellular Communication	Patients who had undergone surgery only had adenomas in which focal inflammation predominated.	7528179
Inflammation, Liver carcinoma, Hepatitis C	Altered Intercellular Communication	In fact, the persistence of HCV infection is permitted by avoidance of viral clearance, despite chronic inflammation in the liver; this process ends with the development of hepatocellular carcinoma in many patients.	7528637
Inflammation, Asthma	Altered Intercellular Communication	To understand the mechanisms of eosinophil migration to the site of inflammation, we examined the expression of adhesion molecules in the bronchial tissues of asthmatic subjects with air flow limitation.	7529029
Neuroepithelial, Perineurial, and Schwann Cell Neoplasm, Skin Basal Cell Carcinoma, Inflammation, Neoplasms	Altered Intercellular Communication	Cases selected included morpheaform basal cell carcinomas, perineural tumors, and sections with dense inflammation without apparent tumor.	7529778
Inflammation, Neoplasms	Altered Intercellular Communication	Three patients presented signs of inflammation or softening at one tumour site.	7530984
Inflammation	Altered Intercellular Communication	These discrepancies were due to the differences in response time of each acute phase protein after the start of inflammation.	7531252
Inflammation	Altered Intercellular Communication	The measurement of serum concentration of IL-6 may be useful for early detection of acute inflammation.	7531252
Malignant neoplasm of liver, Hepatitis	Altered Intercellular Communication	Serum levels of AFP (greater than 20.0 ng/ml, AAT (greater than 170.0 mg/dl) and direct: total bilirubin ratio (greater than 0.5) which indicate absence of predisposition to liver cancer in all the subjects but suggestive of liver inflammation were noted in both the AFB1+ and AFB1- subjects.	7532124
Hepatitis	Altered Intercellular Communication	The pattern of distribution of the aflatoxins in the subjects suggests that the suspected liver inflammation may involve other factors and may not only be due to the present intake levels of aflatoxins.	7532124
Inflammation	Altered Intercellular Communication	These results suggest that G-cells in the antral mucosa are not functionally affected by the inflammation.	7532445
Inflammation	Altered Intercellular Communication	This protects tissues from leakage of noxious contents from dying cells and may promote resolution of inflammation.	7532668
Communicable Diseases, Inflammation	Altered Intercellular Communication	Cytokines are molecules released by inflammatory cells at the site of infection and are potent mediators of inflammation and the immune response.	7532849
Tumor necrosis, Inflammation, Cholesteatoma	Altered Intercellular Communication	Tumor necrosis factor-alpha, interleukin-1, and interleukin-6 appear to be involved in the inflammation and resultant remodeling associated with cholesteatoma.	7532849
Inflammation, Pyelonephritis, Chronic infectious disease, prostatitis, Prostatic Adenoma, Nephrolithiasis	Altered Intercellular Communication	Such wide-spread urological diseases as nephrolithiasis and prostatic adenoma requiring surgical management are often associated with chronic infection or inflammation (pyelonephritis, prostatitis, adenomitis).	7532881
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Hepatocytic CK inclusions were infrequent in patients with normal liver histology, portal fibrosis and/or portal inflammation.	7533231
Neurogenic Inflammation	Altered Intercellular Communication	In experimental studies, tachykinins, especially substance P (SP), cause many of the pathophysiological features of neurogenic inflammation.	7533601
Airway structure, Asthma, Bronchitis	Altered Intercellular Communication	It is unclear whether these peptides are involved in human airway inflammation in diseases such as asthma and chronic bronchitis.	7533601
Bronchitis, Chronic, Neurogenic Inflammation, Asthma, Inflammatory airway disease	Altered Intercellular Communication	To elucidate the relation between neurogenic inflammation and airway inflammatory diseases, we examined the SP concentration in sputum after hypertonic saline inhalation challenge in patients with asthma, patients with chronic bronchitis, and normal volunteers.	7533601
Neurogenic Inflammation, Asthma, Bronchitis	Altered Intercellular Communication	These data suggest that neurogenic inflammation may be involved in the airway inflammatory process and subsequent airway narrowing not only in asthma but also in chronic bronchitis.	7533601
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Focal PZ hypervascularity at CDS is associated with an increased likelihood of prostate cancer or inflammation at biopsy, often without a focal gray-scale abnormality.	7534429
Fibrinoid necrotizing inflammation	Altered Intercellular Communication	In spite of the proliferation of the lining cell layer in rheumatoid inflammation, the extracellular matrix stays very similar to that in normal and osteoarthritic synovium, whereas the pattern of the adhesion receptors is completely altered.	7535359
Inflammation, Tissue injury	Altered Intercellular Communication	No reduction in inflammation was evident on light microscopy, nor was there any evidence of tissue injury on gross inspection or light microscopy.	7535361
Inflammation	Altered Intercellular Communication	These molecules play key roles in lymphocytic infiltration and interactions during tissue inflammation and are in large part normally not expressed by CNS cells.	7536402
Hemoperfusion, Colitis	Altered Intercellular Communication	Concentrations of seromucoids, orosomucoid, alpha 1-antitrypsin changed in correlation with clinical manifestations of colon inflammation and may serve as criteria of hemosorption efficacy.	7536960
Inflammation	Altered Intercellular Communication	In contrast to the peripheral blood, RA synovial fluid T cells were almost exclusively CD28+, suggesting that migration of CD28+CD8+ T cells to active sites of inflammation may occur.	7538295
Refractory anemias, Inflammation	Altered Intercellular Communication	Functionally intact CD28+ T cells may contribute to the abnormal immunoregulation and joint inflammation in RA.	7538295
Inflammation, Destruction (action)	Altered Intercellular Communication	The spatial distribution of aortic microvessels was compared with that of elastin destruction and chronic inflammation.	7539511
Inflammation	Altered Intercellular Communication	Evidence of medial neovascularization was generally not observed in normal aorta or AOD, whereas AAAs showed strong spatial correlations between MNV, disruption and degradation of elastin, and chronic inflammation in the outer aortic wall.	7539511
Inflammation	Altered Intercellular Communication	The presence and density of MNV in the abdominal aorta is a consistent histopathologic marker of aneurysmal degeneration that is spatially correlated with the destruction of elastin and chronic inflammation.	7539511
Refractory anemias, Inflammation	Altered Intercellular Communication	The strong vascular expression of E-selectin indicates an activation of endothelial cells in the recruitment of cells associated with the chronic inflammation of RA.	7540009
Inflammation, Arthropathy	Altered Intercellular Communication	Our study demonstrated the expression of ER in arthritic synovium and suggested that estrogen modulates local inflammation in various joint diseases via synoviocytes as well as sublining macrophage-like cells.	7540206
vascular inflammations, Rheumatoid Vasculitis	Altered Intercellular Communication	The aim of this study was to investigate whether levels of circulating adhesion molecules reflect vascular inflammation in rheumatoid vasculitis (RV).	7540479
vascular inflammations	Altered Intercellular Communication	In conclusion we find that determination of cICAM-1 and cICAM-3 may be useful as a marker of vascular inflammation in patients with RV.	7540479
Inflammation	Altered Intercellular Communication	Leukocyte adhesion plays an important role in inflammation.	7540697
Inflammation, Pancreatitis, Serum Amylase Increased	Altered Intercellular Communication	Pancreatitis is accepted as an uncommon complication of parathyroid surgery, but it has been suggested that up to 35% of patients may experience hyperamylasaemia after parathyroidectomy indicating subclinical inflammation of the pancreas.	7540815
Pancreatitis, Acute, Serum Amylase Increased	Altered Intercellular Communication	Despite highly significant changes in serum parathormone, calcium and phosphate levels postoperatively, there was no evidence in any patient of acute pancreatic inflammation or hyperamylasaemia.	7540815
Communicable Diseases, Inflammation	Altered Intercellular Communication	The absence of chronic antral inflammation was the best method to exclude infection.	7540995
Inflammation	Altered Intercellular Communication	Stratification of results by clinical characteristics showed that UBT and chronic inflammation were the best predictors of H. pylori status in patients older than 60 years of age.	7540995
prostatitis	Altered Intercellular Communication	The high PSA group had larger prostates (68 versus 33 cc, p = 0.0001) and significantly more subclinical prostatic inflammation.	7541857
Inflammation	Altered Intercellular Communication	Acute and chronic inflammation was more prevalent in the high PSA group (63% versus 27%, p = 0.0001 and 99% versus 77%, p = 0.0001, respectively).	7541857
Inflammation, Calculus of prostate	Altered Intercellular Communication	A simultaneous regression analysis showed that prostatic size accounted for 23%, inflammation 7%, prostatic calculi 3% and nonisoechoic ultrasound lesions 1% of the serum PSA variance.	7541857
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Prostate volume and inflammation are the most important factors contributing to serum PSA elevation in men without clinically detectable prostate cancer.	7541857
Hepatic inflammation, Liver Cirrhosis	Altered Intercellular Communication	This may result in low grade hepatic inflammation and may explain the progression to cirrhosis in patients with AICH despite immunosuppressive therapy.	7542148
prostatitis	Altered Intercellular Communication	Histologically, preoperative administration of Eviprostat improved the degree of prostatic inflammation.	7542229
Inflammation	Altered Intercellular Communication	The histological observations of non-CF and CF nasal polyp tissue indicated that the huge variations in the expression and distribution of the CFTR protein were associated with the variations in the degree of surface epithelium remodeling and inflammation in the lamina propria.	7544810
Inflammation, Basal cell hyperplasia	Altered Intercellular Communication	A surface epithelium, showing a slight basal cell hyperplasia phenotype associated with diffuse inflammation, was mainly characterized by a CFTR protein distribution at the apex of ciliated cells in both non-CF and CF specimens.	7544810
Inflammation	Altered Intercellular Communication	In contrast, in a remodeled surface epithelium associated with severe inflammation, CFTR protein presented either a diffuse distribution in the cytoplasm of ciliated cells, or was absent.	7544810
Inflammation	Altered Intercellular Communication	Airway surface epithelium remodeling and inflammation could play a critical role in the posttranscriptional and/or the posttranslational regulation of the CFTR protein expression in non-CF and CF airways.	7544810
Inflammation, Carcinoma of lung	Altered Intercellular Communication	We found that normal human respiratory tract from nose to alveoli express MCP, DAF, and CD59, but not CR1, and that this expression increases in inflammation and in lung cancer.	7545058
allergic inflammation, Asthma attack	Altered Intercellular Communication	These results suggest that higher levels of sVCAM-1 during asthma attacks may reflect the up-regulation of VCAM-1 expression in allergic inflammation, and that a soluble form of VCAM-1 molecules may be useful markers for the presence of allergic inflammation.	7545095
Inflammation, Necrosis	Altered Intercellular Communication	Poorly defined nodule or lobular consolidation usually consists of central caseation necrosis and peripheral nonspecific inflammation.	7546270
Vulvitis, Psoriasiform eczema, Inflammation, Psoriasis, Inflammatory dermatosis, Lichen Simplex Chronicus, Lichen Sclerosus et Atrophicus, Dermatitis, Lichen Planus, Dermatophytosis	Altered Intercellular Communication	The histological diagnoses were lichen sclerosus 25%, lichen simplex chronicus 35%, non-erosive inflammatory dermatoses comprising psoriasis, spongiotic dermatitis, dermatophytosis and psoriasiform dermatitis 13%, erosive vulvitis and lichen planus 9%, nonspecific inflammation 6%, miscellaneous 9% and normal 4%.	7547733
Inflammation, Hyperplasia	Altered Intercellular Communication	The clinical syndrome of vestibulitis did not have a specific histological picture, and biopsies showed nonspecific inflammation, mild hyperplasia or were normal.	7547733
Osteomyelitis, Inflammation, Squamous cell carcinoma, chronic	Altered Intercellular Communication	Squamous cell carcinoma without accompanying osteomyelitis is a rare complication in chronic soft tissue inflammation.	7548253
Inflammation, Hemorrhage, colon (non-specific) lesion, Edema	Altered Intercellular Communication	Autopsy revealed a colon lesion characterized by suppurative inflammation associated with marked edema and hemorrhage in the submucosa.	7549139
Glaucoma, CTCAE, Exfoliation Syndrome, Traumatic injury, Intraocular inflammation	Altered Intercellular Communication	The average age of the patients in Munich was 65 years, and most of them presented with glaucoma caused by iris neovascularization (42%), followed by exfoliation syndrome (14%), intraocular inflammation (11%), trauma (10%) and preceding ocular surgery (9%).	7549351
Inflammation	Altered Intercellular Communication	Other causes were earlier operations (17%), inflammation (16%), lentogenous changes (10%) and neovascularizations (10%).	7549351
Airway structure, Bronchitis, Chronic	Altered Intercellular Communication	Effect of smoking cessation on airway inflammation in chronic bronchitis.	7551380
Communicable Diseases, Inflammation	Altered Intercellular Communication	Scintigraphic techniques for delineation of infection and inflammation.	7551494
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Eleven patients (10 per cent) required conversion to open CBD exploration, and laparoscopic exploration was not attempted in six (5 per cent) because of inflammation or fibrosis.	7552015
Inflammation, Prostatic Intraepithelial Neoplasias, Prostate carcinoma, Benign prostatic hypertrophy	Altered Intercellular Communication	Twenty-five patients (14.6%) had prostate cancer, 127 (74.2%) had benign prostate hypertrophy, four (2.3%) had prostatic intraepithelial neoplasia, eleven (6.4%) had inflammation, and four (2.3%) had normal prostate tissue.	7553283
Cheilitis, Inflammation	Altered Intercellular Communication	Thirty six Chinese adults with angular cheilitis; 28 controls matched for age and sex, with no inflammation.	7553380
Inflammation	Altered Intercellular Communication	A sono-guided percutaneous liver biopsy specimen demonstrated only chronic fibrosing inflammation.	7553413
Hepatitis A, Macrovesicular hepatic steatosis, Inflammation, Nonalcoholic Steatohepatitis	Altered Intercellular Communication	Hepatitis C viral infection can also cause macrovesicular steatosis and such inflammation of the liver as nonalcoholic steatohepatitis.	7553425
Dystrophy, Pain Distress Question, Inflammation	Altered Intercellular Communication	We report on Sudeck's dystrophy in a 69-year-old woman who complained of recurrent pain and local inflammation in the right hand.	7553435
Inflammation, Periodic Fever Syndrome	Altered Intercellular Communication	Elevated serum level and altered glycosylation of alpha 1-acid glycoprotein in hyperimmunoglobulinemia D and periodic fever syndrome: evidence for persistent inflammation.	7554449
Inflammation, Fever	Altered Intercellular Communication	Despite the clinical picture of recurrent febrile attacks with asymptomatic intervals, these studies indicate that hyperimmunoglobulinemia D should be considered a condition of persistent inflammation.	7554449
Exophthalmos, Temporal Arteritis, Orbital Pseudotumor	Altered Intercellular Communication	We report a patient presenting with bilateral exophthalmos associated with CT and MRI signs of orbital inflammation, who had biopsy-proven temporal arteritis.	7554567
Granulomatous inflammation, Giant Cells, Langhans, Necrosis	Altered Intercellular Communication	On laparotomy, the pyloroduodenal area was extrinsically compressed by surrounding lymph nodes, which, on biopsy, contained granulomatous inflammation with caseation necrosis and Langhan's giant cells.	7555442
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Somatostatin 14 and joint inflammation: evidence for intraarticular efficacy of prolonged administration in rheumatoid arthritis.	7555618
Arthritis, thermography	Altered Intercellular Communication	Additionally, telethermography was performed to evaluate the intensity of the joint inflammation.	7555618
Inflammation, Pain Distress Question	Altered Intercellular Communication	Our results indicate the analgesic property of SST14 and demonstrate its capacity to reduce progressively joint inflammation confirmed by thermography and by reduction of pain, after a month of therapy.	7555618
Airway structure, Asthma	Altered Intercellular Communication	Glycemic status may then have some role in determining the amount of superoxide production, and therefore airway inflammation, in asthma.	7556586
Intestinal metaplasia, Mucous Membrane, Stomach Carcinoma	Altered Intercellular Communication	Abnormal intercellular communication thus may play an important role in the progression from mucosal injury to intestinal metaplasia and/or gastric carcinoma.	7557130
Uterine Inertia, Colitis	Altered Intercellular Communication	Colonic inflammation may lead to motility disturbances, including severe atony.	7557131
deficiency aspects, hormone deficiency, Stanford Cancer Institute	Altered Intercellular Communication	Aging is associated with relative growth hormone and/or testosterone (T) hormone deficiency, and those with SCI may have a premature deficiency of these two hormones.	7557841
deficiency aspects, hormone deficiency, Stanford Cancer Institute	Altered Intercellular Communication	Aging is associated with relative growth hormone and/or testosterone (T) hormone deficiency, and those with SCI may have a premature deficiency of these two hormones.	7557841
Inflammation, "Dupuytrens Disease	Altered Intercellular Communication	These appearances are very similar to those in Dupuytren's disease of the hand, with no inflammation and no synovial involvement.	7559688
Inflammation	Altered Intercellular Communication	In tissue from this patient there was evidence of chronic inflammation and a marked macrophage response.	7559896
Inflammation, Fibrosis Assessment, Solar elastosis	Altered Intercellular Communication	There was increased solar elastosis (p < .0001), dermal elastic tissue (p < .0001), melanophages (p < .0001), perivascular inflammation (p < .05) and perifollicular fibrosis (p < .01) but no change in the number of mast cells or dermal mucin in the photo exposed skin.	7560349
Inflammation, Uveitis	Altered Intercellular Communication	Intermediate uveitis presents a characteristic clinical picture with inflammation in the vitreous and peripheral retina.	7560782
Inflammation	Altered Intercellular Communication	Reduction of UV-induced inflammation by fish oil may be due, at least partially, to lowered prostaglandin E2 levels.	7561154
Inflammation, Periodontal Diseases	Altered Intercellular Communication	Platelet-activating factor (PAF), a potent phospholipid inflammatory mediator, is increased in the mixed saliva of subjects with periodontal disease and correlates with the extent of oral inflammation.	7562354
Inflammatory abnormality of the eye, Hearing problem, Oculovestibuloauditory syndrome	Altered Intercellular Communication	Cogan's syndrome is an uncommon disease characterized by ocular inflammation, vestibuloauditory dysfunction and symptoms of systemic disease.	7564135
Inflammatory abnormality of the eye, Keratitis, Episcleritis, Scleritis	Altered Intercellular Communication	Five of our patients not only presented with keratitis but also demonstrated signs of ocular inflammation diagnosed as scleritis or episcleritis.	7564135
Deafness, Inflammatory abnormality of the eye, Hearing problem	Altered Intercellular Communication	The importance of being aware that vestibuloauditory dysfunction may occur in patients with ocular inflammation, and the fact that early immunotherapy may prevent the risk of deafness, has to be emphasized.	7564135
Diabetes Insipidus, Visual disturbance	Altered Intercellular Communication	Postoperatively, the patient's visual disturbance improved, but diabetis insipidus appeared and required hormonal replacement.	7566427
Inflammation, Immobile, Muscle damage, Granulation finding	Altered Intercellular Communication	Nasogastric tubes have been shown to cause damage to the pharyngolaryngeal complex, producing laryngeal inflammation, granulation, muscle damage, and even vocal cord immobility.	7567009
Carcinoma of lung, Pneumonitis	Altered Intercellular Communication	Lung cancer is registered more frequently in males aged from 50 to 70, smokers, with a history of bronchopulmonary inflammation.	7567864
Inflammation, Dental Plaque	Altered Intercellular Communication	The clinical effectiveness of a new flossing device, the Floss Plus easy flosser, in reducing interproximal plaque and interproximal gingival inflammation was compared to the effectiveness of hand-held floss.	7568747
Inflammation, Dental Plaque	Altered Intercellular Communication	All groups experienced a significant decrease in the amount of interproximal inflammation and plaque, regardless of which flossing method was used.	7568747
Inflammation, Dental Plaque	Altered Intercellular Communication	There was no statistically significant difference between the two flossing methods in the reduction of interproximal inflammation or plaque.	7568747
Chronic Obstructive Airway Disease	Altered Intercellular Communication	Hormonal, renal, and autonomic nerve factors involved in the excretion of sodium and water during dynamic salt and water loading in hypoxaemic chronic obstructive pulmonary disease.	7570434
Neurogenic Inflammation, Opportunistic Infections	Altered Intercellular Communication	Bacteriological examination of the urine from 1138 elderly patients (50-80 years of age) with urogenital inflammation determined the predominant contamination of the urine with gram-negative opportunistic agents in titers 10(3)-10(7) CFU/ml.	7571191
Inflammation, Pulmonary Valve Insufficiency, Obesity	Altered Intercellular Communication	Obesity was present in 318 patients (15.8%), respiratory insufficiency in 75 (3.7%), inflammation in 251 (12.5%), and common bile duct (CBD) stones in 83 (4.1%).	7571675
Osteogenesis, Inflammation, Spondylitis, Collagen Diseases	Altered Intercellular Communication	Ankylosing spondylitis is a systemic rheumatologic disorder of adults that results in disease-specific inflammation and eventual ossification at the site of ligamentous insertion into bone.	7572504
Inflammation, Carcinogenesis, Metaplasia, Esophagitis, Adenocarcinoma Of Esophagus	Altered Intercellular Communication	In this study, we investigated the potential relationship between E-cadherin expression and inflammation, metaplasia, and carcinogenesis in esophagitis, BE, and esophageal adenocarcinoma.	7572899
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Sections were scored blindly for degree of active and chronic inflammation and extent of H. pylori infection.	7572902
Inflammation, Infection caused by Helicobacter pylori, Ulcer	Altered Intercellular Communication	The reduction of H. pylori infection, but not ulcer healing per se, correlated with the decrease in active and chronic antral inflammation.	7572902
Inflammation, Macular Edema, Cystoid	Altered Intercellular Communication	Except for the cellular membranes, each eye was without evidence of inflammation or cystoid macular edema.	7573304
Asthma	Altered Intercellular Communication	These observations have implications for the pathophysiology and treatment of both asthma and tobacco smoke-induced airway inflammation.	7573463
Inflammation	Altered Intercellular Communication	Inflammation at the epidural catheter insertion site occurred in 3.8% (38), of which 42% (16) had some cutaneous purulence detected.	7574052
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	A palliative operation was performed, but histological examination of pancreatic specimen suggested only chronic inflammation and no evidence of malignancy.	7575086
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To investigate the extent to which early radiologic damage is predicted by joint inflammation in patients with newly diagnosed rheumatoid arthritis (RA).	7575696
Arthritis, Rheumatoid Factor	Altered Intercellular Communication	Odds ratios for progression of total damage were 12 for the presence of rheumatoid factor, 5 for the presence of damage at baseline, and 2 for cumulative joint inflammation.	7575696
Arthritis	Altered Intercellular Communication	A positive association between continued joint inflammation and progression of damage was found to be statistically significant for most joint groups.	7575696
Refractory anemias, Arthritis, Rheumatoid Factor	Altered Intercellular Communication	Progression of radiologic damage in patients with newly diagnosed RA is independently associated with the presence of rheumatoid factor and damage at baseline and with cumulative joint inflammation.	7575696
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Reduction of synovial inflammation after anti-CD4 monoclonal antibody treatment in early rheumatoid arthritis.	7575695
Osteoporosis	Altered Intercellular Communication	Our data evidence the importance of immobilization osteoporosis and point to the role of hormonal factors in its pathogenesis.	7577312
Sepsis, Interstitial inflammation	Altered Intercellular Communication	Persistence of interstitial inflammation after episodes of cardiac rejection associated with systemic infection.	7578188
Communicable Diseases, Interstitial inflammation	Altered Intercellular Communication	Patients with rejection and infection showed persistent interstitial inflammation longer than patients with only rejection and was most often represented by International Society for Heart and Lung Transplantation rejection grade 1B.	7578188
Communicable Diseases, Interstitial inflammation	Altered Intercellular Communication	Although further evaluation of these findings is necessary, we speculate that heart transplant recipients with systemic infection and acute rejection have greater immunologic activity leading to persistent interstitial inflammation and may possibly be associated with a higher incidence of chronic rejection.	7578188
Inflammation, Gangrene	Altered Intercellular Communication	The six patients who did not respond had pathologic evidence of transmural inflammation, and five had a gangrenous wall.	7579876
Sarcoma, Myositis, CTCAE 5.0	Altered Intercellular Communication	Focal myositis is a rare, benign inflammatory condition that may clinically simulate a soft tissue sarcoma.	7580245
Inflammation, Thyroid associated opthalmopathies	Altered Intercellular Communication	MR T2 relaxation time for the assessment of retrobulbar inflammation in Graves' ophthalmopathy.	7580266
Thyroid Diseases, physiopathological, Goiter	Altered Intercellular Communication	history of thyroid disease or goitre or any clinical sign of hormonal dysfunction.	7581944
Inflammation, Dysplasia, Carcinoma, SERPINB3 wt Allele, Squamous cell carcinoma, Family history, Dysautonomia, Familial, Lichen Planus, Hyperplasia	Altered Intercellular Communication	Nine normal (N) samples were taken from the resection margins of benign lesions; the pathological lesions were classified as chronic inflammation (CI; n = 11), fibrous hyperplasia (FH; n = 12), lichen planus (LIP; n = 8), dysplasia (DYS; n = 5), squamous cell carcinoma (SCC; n = 25; well differentiated [SCCWD]; n = 10; moderately to poorly differentiated [SCCMPD]; n = 15) and epithelium adjacent to carcinomas (EAC; n = 6).	7582244
Inflammation, Asthma	Altered Intercellular Communication	We speculate that the inflammation in the airways of asthmatic patients itself tends to increase the serum IgE level, possibly secondary to mediators that it generates.	7582283
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Alveolar inflammation and its relation to emphysema in smokers.	7582312
Inflammation, Synovitis	Altered Intercellular Communication	Clinical evidence of synovitis was observed in 30 (88%) and joint inflammation was detected in 31 (91%) by the above-mentioned imaging techniques.	7582722
Airway structure, Asthma, Bronchitis	Altered Intercellular Communication	Granulocyte-macrophage colony stimulating factor (GM-CSF) and interleukin (IL)-5 or IL-8 have been suggested to play an important role in the pathogenesis of eosinophilic airway inflammation in bronchial asthma or neutrophilic airway inflammation in chronic bronchitis, respectively, However, GM-CSF and IL-8 have biological activities to either eosinophils or neutrophils.	7584683
Airway structure, Asthma, Bronchitis	Altered Intercellular Communication	To investigate the contribution of these cytokines to airway inflammation, we compared the cellular differential and immunolocalization of GM-CSF, IL-5 and IL-8 in sputum cells from patients with bronchial asthma and chronic bronchitis.	7584683
Bronchitis, Chronic, Airway structure	Altered Intercellular Communication	The immunochemical comparison of GM-CSF and IL-8 localization in sputum cells between bronchial asthma/chronic bronchitis suggests the differential regulation and roles of these cytokines in eosinophilic vs neutrophilic airway inflammation, resulting in the development of different types of airway inflammation.	7584683
Thalassemia, Turner Syndrome, Hypogonadotropic hypogonadism	Altered Intercellular Communication	In this patient, thalassemia major and its lifelong consequences, namely the hemochromatosis-related hypogonadotrophic hypogonadism, masked the usual hormonal findings of Turner's syndrome.	7584702
Inflammation	Altered Intercellular Communication	Granulomatous inflammation of the pituitary and pituitary abscesses are rare entities.	7584709
Meningism, Non-necrotizing granulomatous inflammation, Pituitary Apoplexy, Hypopituitarism, Abscess of pituitary	Altered Intercellular Communication	We report a case of a radiographic and clinical, sterile pituitary abscess with non-caseating granulomatous inflammation in a girl who presented with hypopituitarism, meningeal irritation, and symptoms of pituitary apoplexy.	7584709
Communicable Diseases	Altered Intercellular Communication	Ischemic, infectious, and inflammatory conditions were considered in the differential diagnosis.	7584757
Inflammation, Chronic keratitis	Altered Intercellular Communication	In the patients with chronic keratitis the reaction tended to be focal and accompanied by inflammation; in those with degenerative pannus the reaction was diffuse and accompanied by minimal inflammation.	7585313
Communicable Diseases, Inflammation	Altered Intercellular Communication	The patients were divided into two groups with infective disease (severe and moderate) and one group with non-infective inflammation.	7586591
Reiter Syndrome, Orchitis	Altered Intercellular Communication	Tc-99m MDP bone scans were used to evaluate the articular inflammation in 38 patients with Reiter's disease and compared with clinical examination and radiologic findings.	7586982
Arthritis, Reiter Syndrome, Orchitis	Altered Intercellular Communication	In view of the advantages of low patient radiation exposure, high sensitivity, and the ability to survey the whole body, we consider bone scintigraphy as useful and better than radiography in the detection of early articular inflammation and in establishing the extent and pattern of arthritis in Reiter's disease.	7586982
Airway structure, Communicable Diseases	Altered Intercellular Communication	A human model of gram-negative infection and airway inflammation.	7587436
Airway structure, Colonization	Altered Intercellular Communication	However, useful parameters to objectively describe the airway inflammation associated with airway instrumentation and colonization have not been well define.	7587436
Airway structure, Communicable Diseases, Dependence on ventilator	Altered Intercellular Communication	In our respiratory care unit, patients who are medically stable except for ventilator dependence are readily available for longitudinal assessment of airway secretions and therefore provide a unique population for studying airway inflammation and infection.	7587436
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Increase in the number of substance P nerve fibers is in accordance with the hypothesis that substance P contributes to neurogenic mediation of inflammation in ulcerative colitis.	7587798
Inflammation, Necrosis	Altered Intercellular Communication	There was associated inflammation and fat necrosis in the surrounding periesophageal soft tissue.	7587817
Airway structure, Wheezing	Altered Intercellular Communication	TFV responsiveness to salbutamol and s-ECP levels correlate strongly, both probably reflecting airways inflammation, and may possibly be valuable prognostic tools in recurrent wheezy infants and toddlers.	7589400
Hyperprolactinemia	Altered Intercellular Communication	Opioidergic but not dopaminergic neurotransmission plays a direct role in the suppression of LH secondary to hyperprolactinemia.	7589643
Duodenal Ulcer, Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Helicobacter pylori infection density and gastric inflammation in duodenal ulcer and non-ulcer subjects.	7590424
Inflammation, Necrosis	Altered Intercellular Communication	Histological examination of percutaneous liver biopsy specimens showed dense portal inflammation with piecemeal necrosis.	7590582
Inflammation, Granuloma	Altered Intercellular Communication	Lobular inflammation was present mederately and a large well-organized epitheloid granuloma was found within a liver lobule.	7590582
Inflammation, Hypopigmentation disorder, VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)	Altered Intercellular Communication	The lack of any preceding inflammation in the affected areas and the subsequent widespread spontaneous depigmentation that occurred within 1 year pointed to a diagnosis of "pentachrome vitiligo."	7593796
Inflammation, Hypertension, CTCAE, Cardiolipins, Diabetes Mellitus	Altered Intercellular Communication	Subjects were compared for the prevalence of anticardiolipin and antiendothelial cell antibodies, altered serum lipoprotein levels, smoking, diabetes, hypertension, and signs of inflammation.	7595183
Malignant Neoplasms, Neoplasms	Altered Intercellular Communication	The predictive value of a positive test for malignant tumours, benign tumours and inflammatory conditions was 66%, 94% and 75%, respectively.	7598416
Granulomatous inflammation, Cerebellar vermis structure	Altered Intercellular Communication	Biopsies taken from the cerebellar vermis and the roof of the fourth ventricle, showed granulomatous inflammation due to eggs.	7598827
Inflammation	Altered Intercellular Communication	The antigens recognized by the RM 3/1- (intermediate stage inflammation marker) and 25 F 9-antibodies (late stage inflammation marker) were expressed exclusively by histiocytes and inflammatory cells that had migrated from the blood vessels as part of the acute inflammatory response associated with an intravital reaction.	7599096
Panacinar Emphysema, Airway structure, Small airways disease, Centriacinar Emphysema, Anatomical site notation for tumour staging PLE	Altered Intercellular Communication	Based on our previous finding, of increased small airways disease in centrilobular emphysema (CLE) when compared with panlobular emphysema (PLE), we hypothesized that smokers who develop CLE would have increased airway responsiveness associated with airway inflammation and exaggerated airway narrowing, but not smokers with PLE.	7599834
Communicable Diseases, Inflammation, Superficial ulcer	Altered Intercellular Communication	Because suture erosion after keratoplasty is an important risk factor for inflammation, infection, vascularization, and graft rejection, we aimed to delineate patient characteristics associated with these erosions.	7600806
Gingivitis, Calculi, Dental Plaque	Altered Intercellular Communication	The subjects were examined clinically for the presence of plaque, calculus, gingival inflammation, periodontal probing depths and gingival recessions.	7601915
Inflammation, Dental Plaque	Altered Intercellular Communication	The risk factors for gingival recession were identified as age of 35 years or more, male sex, lower educational status, presence of plaque and gingival inflammation.	7601915
Microcytosis, Acute inflammation	Altered Intercellular Communication	A similar pattern was observed in patients with microcytosis (MCV < 84 fL) associated with low % TS; dividing this subgroup according to SF values (low, < 30 micrograms/L) did not provide more information because patients with acute inflammation were excluded.	7602028
Inflammation, Anemia, Chronic disease	Altered Intercellular Communication	Patients with acute inflammation present altered iron status indexes that resemble those observed in the anemia of chronic disease.	7602028
Microcytosis, Inflammation	Altered Intercellular Communication	The concomitant presence of microcytosis and low % TS, and to a lesser extent the presence of one of these alterations, is suggestive of iron deficiency associated with inflammation and may warrant gastrointestinal tract investigations and ferrous salt treatment.	7602028
Inflammation	Altered Intercellular Communication	In 20 (36%) observations the histological changes were like in acute, and in 36 (64%)--like in chronic inflammation.	7602934
Inflammation, Arteritis	Altered Intercellular Communication	Histologically, there was mild inflammation in the intima and media of the aorta and the large pulmonary arteries, consistent with nonspecific arteritis.	7604838
Inflammation, Dysplasia, Gastritis, Hyperplasia	Altered Intercellular Communication	It is in the gastrobiopsies that morphological features of chronic gastritis--inflammation and activity according to the International Classification of Gastritis (1990)--are more pronounced in the atypical hyperplasia and dysplasia than in normal epithelium.	7605222
Inflammation	Altered Intercellular Communication	Peripancreatic inflammation was detected in only 29% patients on US compared with 91% on CT. Pancreatic abscesses were detected in 8 patients on CT and gas was present in all of them.	7605319
Inflammation	Altered Intercellular Communication	On follow up after 3 months, worsening of inflammation was detected in 11% patients on CT, which was not detected on US.	7605319
Abscess, Pancreatitis, Hemorrhage	Altered Intercellular Communication	It is concluded from this study that CT is far superior to US in the evaluation of acute pancreatitis, detection of peripancreatic inflammation and its extension into the retroperitoneal compartments and mesentery, and also for the evaluation of fluid collections, haemorrhage and abscesses.	7605319
Granulomatous inflammation	Altered Intercellular Communication	Microscopic study disclosed granulomatous inflammation with many giant cells in the walls of small and medium sized vessels, and the adventitia and media were more involved than the intima.	7605690
Herpes Simplex Infections, Viral meningitis, Herpes zoster disease	Altered Intercellular Communication	Since the blood vessels in the central nervous system play an important part in any inflammatory conditions and the blood vessels may be involved by bacterial, fungal, parasitic or viral meningitis, various microorganisms have been suspected as the cause of GANS, including mycoplasma, herpes zoster, herpes simplex viruses, cytomegalovirus, and human T-lymphotropic virus type III (HTLV-III).	7605690
Inflammation, Gastritis	Altered Intercellular Communication	Antral inflammation scores (scale, 0-6) for the NSAID group were: week 0--1.2 +/- 0.3; week 1--1.1 +/- 0.3; week 4--1.3 +/- 0.3; findings of 'chemical gastritis' were not seen.	7605852
Inflammation	Altered Intercellular Communication	MIP-1 alpha is a neutrophil chemotactic protein important in acute and chronic inflammation.	7606866
Inflammation	Altered Intercellular Communication	Inflammation and renal function deteriorated despite transvenous administration of antibiotics.	7608599
Inflammation, Fatty degeneration, Granulomatous hepatitis	Altered Intercellular Communication	Liver biopsy done in two other patients revealed a mild granulomatous hepatitis in one and nonspecific changes (i.e., steatosis and a mild inflammation) in the other.	7608823
Inflammation	Altered Intercellular Communication	Capsaicin induces the release of substance P (SP) by PAFs, producing vasodilation and increasing vascular permeability (neurogenic inflammation).	7608871
Sepsis, Multiple Myeloma, Inflammation, SLC25A10 gene	Altered Intercellular Communication	Although inflammation reduced after the placement of drains, the patient with multiple myeloma died of sepsis and DIC.	7609356
Inflammation	Altered Intercellular Communication	However an inflammation of the optic nerve as a result is rare.	7609388
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Non-osseous tissue adjacent to devices of both materials showed fibrosis, including areas of mild chronic inflammation.	7610777
Cataract, Inflammation	Altered Intercellular Communication	[Anterior chamber inflammation after cataract intraocular lens surgery in postvitrectomy eyes].	7611006
Cataract, Inflammation	Altered Intercellular Communication	We determined the anterior chamber inflammation by means of laser flaremetry after cataract intraocular lens surgery for the nuclear cataract that developed after vitrectomy.	7611006
Inflammation, Pneumonia, Airway structure, cytoplasmic antineutrophil cytoplasmic antibody, Bronchiolitis Obliterans	Altered Intercellular Communication	Airway lesions including bronchiolitis obliterans organizing pneumonia (4 patients, 19%), necrotizing granulomatous inflammation (4 patients, 15%), and non-granulomatous inflammation (3 patients, 11%) were more commonly associated with patients with C-ANCA.	7611186
Necrotizing granulomatous inflammation, Inflammation, interstitial, Fibrosis Assessment	Altered Intercellular Communication	Interstitial lesions were found in 20 patients (74%), and included necrotizing granulomatous inflammation (8 patients, 30%), fibrosis (13 patients, 48%), and chronic inflammation (12 patients, 44%).	7611186
Mucous Membrane, Inflammation	Altered Intercellular Communication	Histological assessment for mucosal atrophy and inflammation was performed in gastric biopsy specimens taken from 24 Japanese patients with PA and from 24 age- and sex-matched controls.	7611206
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To evaluate the efficacy of stromelysin-1 (matrix metalloproteinase-3 [MMP-3]) and tissue inhibitor of metalloproteinases-1 (TIMP-1) in serum as markers for joint inflammation in rheumatoid arthritis (RA).	7612046
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	Serum levels of both MMP-3 and TIMP-1 in RA patients were significantly higher than those in OA patients and in healthy controls (P < 0.001), and were shown to correlate with traditional systemic markers of inflammation including the erythrocyte sedimentation rate and C-reactive protein level, and with the Lansbury articular index.	7612046
Refractory anemias, Inflammation	Altered Intercellular Communication	Our results support the notion that levels of both MMP-3 and TIMP-1 in RA patient sera are increased in association with inflammation.	7612046
Inflammation	Altered Intercellular Communication	The lesions displayed marked asymmetry and predominantly involved the side with the most severe inflammation.	7612558
Granulomatosis with polyangiitis, Orbital Pseudotumor	Altered Intercellular Communication	A 'yellow lid' associated with orbital inflammation and is a strong pointer to the clinical diagnosis of Wegener's granulomatosis.	7612558
Inflammation, Asthma	Altered Intercellular Communication	Airway-like inflammation of minor salivary glands in bronchial asthma.	7613185
Inflammation, Asthma	Altered Intercellular Communication	Bronchial asthma is characterized by a chronic inflammation with accumulation of eosinophils, mast cells and activated T lymphocytes that release a large panel of cytokines.	7613185
Inflammation, BALT lymphoma, asthma chronic	Altered Intercellular Communication	We propose that activated T lymphocytes, present in the bronchial mucosal lymphoid tissue in chronic asthma might migrate, colonize other glandular and mucosal sites, and so trigger at a distance, an airway-like inflammation.	7613185
Inflammation, Cystitis, Chief complaint (finding)	Altered Intercellular Communication	From a review of the Japanese literature, the common chief complaint is urine discharge from the umbilicus accompanying cystitis and/or urachal inflammation.	7614387
Cessation of life, Inflammation	Altered Intercellular Communication	This appears to have followed the death of the cysticercus, releasing the cysticercus contents into the surrounding brain and to have stimulated an intense reactive inflammation.	7614768
Inflammation	Altered Intercellular Communication	Responses were independent of the presence or absence of mucosal inflammation.	7615274
Ulcerative Colitis	Altered Intercellular Communication	In ulcerative colitis, a different pattern of abnormality occurs, supporting the notion that the epithelium is also diffusely abnormal independent of mucosal inflammation.	7615274
Inflammation, Swelling	Altered Intercellular Communication	The histological examination of the transplant showed a purulent inflammation, swelling of the parenchym, partly absence of keratocytes and endothel cells, and a defect in the Bowman membrane.	7616724
Degenerative disorder of muscle, Inflammation, Myositis	Altered Intercellular Communication	The unique findings of intracellular amyloid deposits and rimmed vacuoles distinguishing IBM from other inflammatory myopathies, and recognition that suppression of inflammation has no effect on the clinical course, suggest that IBM may represent a degenerative muscle disorder.	7617187
Inflammation	Altered Intercellular Communication	Endoscopic and histological inflammation were scored on 4-point scales.	7624110
Inflammation	Altered Intercellular Communication	Separate data concerning the presence/absence of active inflammation showed a high kappa value (0.74, P < 0.001).	7624110
Papilledema, Intraocular Infection, Vitreous inflammatory cells, Juxtapapillary focal retinitis AND retinochoroiditis, Unspecified visual loss, Diffuse unilateral subacute neuroretinitis	Altered Intercellular Communication	Diffuse unilateral subacute neuroretinitis (DUSN) is characterized by unilateral visual loss with vitreous inflammation, optic disc swelling, and the presence of gray-white lesions in the deep retina, and can be associated with intraocular nematode infection.	7624603
Inflammation, Neoplasms	Altered Intercellular Communication	The importance of mast cells in local homeostasis, inflammation and tumour surveillance is supported by many studies, and the association of mast cells with various neoplasms has been known for a long time.	7625856
Necrotizing granulomatous inflammation, Caseous necrosis	Altered Intercellular Communication	Renal biopsy disclosed interstitial chronic granulomatous inflammation with caseous necrosis and strong nodular mesangial Ig A deposit, along with trace granular Ig G deposition and perivascular C3 deposit.	7626558
Cataract, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Inflammation after cataract extraction and intraocular lens implantation in patients with rheumatoid arthritis.	7626571
Cataract, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	The purpose of this study was to examine whether preoperative activity of rheumatoid arthritis influences the extent of anterior chamber inflammation after cataract extraction and intraocular lens implantation.	7626571
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	Multivariate analysis showed that the titre of rheumatoid factor was the more significant element to determine the persistent aqueous inflammation.	7626571
Rheumatoid Arthritis, Inflammation, Rheumatoid Factor	Altered Intercellular Communication	Intraocular lens implantation is basically a safe procedure for patients with rheumatoid arthritis, although postoperative aqueous inflammation tends to be persistent in patients with high titres of rheumatoid factor.	7626571
MTA2 gene, Inflammation, Alveolitis	Altered Intercellular Communication	The stereotypic value for various PID was the development of alveolitis running in 2 stages: 1) early one, including exudative inflammation and 2) late one, involving sclerotic changes up to the formation of the honeycomb lung.	7626980
Inflammation, Primary malignant neoplasm, Degenerative disorder	Altered Intercellular Communication	Reactive oxygen species are generated physiologically in cells with a significant increase in certain pathological conditions, such as inflammation, cancer, aging, degenerative disease.	7627119
Inflammation, Intracranial Hypertension	Altered Intercellular Communication	Twenty obese females, aged 27-68 years participated in the study of associated symptoms, signs of inflammation in serum, intracranial hypertension and magnetic resonance imaging of the brain (MR).	7627247
Inflammation, Intracranial Hypertension, Obesity	Altered Intercellular Communication	Signs of inflammation in serum, intracranial hypertension and decreased subarachnoidal space were statistically significantly more common in patients with obesity, than in controls.	7627247
Multiple Myeloma, Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation related to amyloid deposition in a focus of multiple myeloma.	7631558
Osteomyelitis, Multiple Myeloma, Inflammatory lesion, Granulomatous inflammation	Altered Intercellular Communication	These seemingly unrelated elements suggested the possibility of a chronic inflammatory lesion of bone, such as osteomyelitis, but ultimately proved to represent multiple myeloma with granulomatous inflammation related to amyloid deposition.	7631558
Necrotizing granulomatous inflammation, Dysplasia	Altered Intercellular Communication	The case demonstrates that the differential diagnosis of chronic granulomatous inflammation with numerous plasma cells, in the appropriate clinical context, includes amyloid in association with a plasma cell dyscrasia.	7631558
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	We suggest that during myocardial ischemia and thrombolysis anticytokine molecules released from the injured myocardium become available to reduce inflammation caused by cytokines and other mediators of inflammation.	7631597
Inflammation, Necrosis, Tabes Dorsalis, Becker Muscular Dystrophy, Fibrosis Assessment	Altered Intercellular Communication	Phospholipase A2 activation may therefore play an important role in the development of inflammation and necrosis, with subsequent fibrosis and massive loss of muscle function, which develops in Duchenne and Becker muscular dystrophy.	7633184
Inflammation, Neoplasms	Altered Intercellular Communication	Tumor of the left main bronchus and severe inflammation of the surrounding mucosa with purulent secretion were found during bronchofiberoscopy.	7633372
Otitis Externa	Altered Intercellular Communication	Anal canal inflammation after ileal pouch-anal anastomosis.	7634974
Pouchitis, Otitis Externa	Altered Intercellular Communication	Anal canal inflammation was evident on both endoscopy and biopsy in 48 patients (22.11 percent); 18 patients (8.29 percent) had a normal ileal pouch (9 had symptoms; 5 required topical treatment), and 30 patients (13.82 percent) had associated ileal pouch inflammation (23 with symptoms requiring systemic treatment because of pouchitis; 10 patients had concomitant topical treatment).	7634974
Inflammation, Pouchitis	Altered Intercellular Communication	Nine (4.1 percent) patients had inflammation of the anal canal alone, and 23 (10.6 percent) had pouchitis in addition.	7634974
Pouchitis, Otitis Externa	Altered Intercellular Communication	The need for treatment occurred in 28 (12.9 percent) of the total ((2.3 percent) patients with anal canal inflammation and 23 (10.6 percent) with anal canal inflammation plus pouchitis).	7634974
Pain Distress Question, Chronic disease of musculoskeletal system, Inflammation	Altered Intercellular Communication	Non-steroidal anti-inflammatory drugs (NSAIDs) are used widely to relieve pain, with or without inflammation, in people with both acute and chronic musculoskeletal disorders.	7635014
Pain Distress Question, Acute onset pain	Altered Intercellular Communication	In this article we review pain relief in the very young, concentrating on the recognition and treatment of acute pain such as occurs with surgery, invasive procedures, injury or acute inflammation.	7635020
Gastric ulcer, Helicobacter pylori, Inflammation	Altered Intercellular Communication	The course of gastric ulcer disease and its relations to certain indicators of inflammation and Helicobacter pylori in the gastric mucosa were examined in a 10-year follow-up.	7638567
Inflammation, Observation Method - Coagulation, Lupus Nephritis	Altered Intercellular Communication	This fact evidences intensity of immune inflammation and coagulation in the kidneys in the above forms of lupus nephritis.	7638767
Inflammation, S100A4 protein, human	Altered Intercellular Communication	The concentration of carcinoembryonic antigen (CEA), known as a marker of malignant transformation and chronic inflammation, is increased in bronchoalveolar lavage fluid obtained from smokers compared with fluid from non-smokers.	7638808
Inflammation, Bile duct structure	Altered Intercellular Communication	Histologic analysis revealed a correlation of alpha GST with both lobular inflammation and bile duct lesions.	7639195
Refractory anemias, Inflammation	Altered Intercellular Communication	Levels of antigenic KS were significantly lower in RA patients and correlated negatively with systemic parameters of inflammation and serum levels of TIMP-1.	7639798
Refractory anemias, Inflammation	Altered Intercellular Communication	The increase in serum levels of MMP-3 and TIMP-1 appears to reflect systemic inflammation in RA.	7639798
Gingivitis, Hemorrhage	Altered Intercellular Communication	Heavy or profuse bleeding and severe gingival inflammation was observed in 3 patients.	7640334
Communicable Diseases, Inflammation	Altered Intercellular Communication	Association of infection and inflammation promoted aggravation of initial immune deficiency.	7642080
Pancreatitis, Acute, Liver Abscess, Acute appendicitis NOS (disorder), Duodenal Ulcer, bowel ischemic, Diverticulitis, Acute cholangitis, Acute inflammation	Altered Intercellular Communication	Eight patients had hyperchogenicity in the right pararenal space, a condition considered to be due to an acute inflammation, including acute pancreatitis, acute cecal diverticulitis, acute appendicitis, ischemic bowel, acute cholangitis, liver abscess, and penetrated duodenal ulcer.	7642766
Malignant Neoplasms	Altered Intercellular Communication	Chronic inflammations of an adjacent organ, a previous history of laparotomy, a malignancy with peritoneal metastases, and treatment with corticosteroid were considered the causes behind the condition in the 19 patients with normal echogenicity.	7642766
Inflammation, Virus Diseases, Chronic infectious disease	Altered Intercellular Communication	In younger patients, the cause of the inflammation was usually viral infectious disease or chronic focal infection.	7643566
Inflammation	Altered Intercellular Communication	Quantification of inflammation in the wrist with gadolinium-enhanced MR imaging and PET with 2-[F-18]-fluoro-2-deoxy-D-glucose.	7644624
Inflammation	Altered Intercellular Communication	To quantify the activity of joint inflammation with magnetic resonance (MR) imaging and positron emission tomography (PET).	7644624
Inflammation	Altered Intercellular Communication	Contrast material-enhanced MR imaging and PET allow quantification of volumetric and metabolic changes in joint inflammation and comparison of efficacies of antiinflammatory drugs.	7644624
Inflammation, Neoplasms	Altered Intercellular Communication	The ureteric stenoses could be classified as congenital (one), secondary to a vascular graft (1), tumour (1) or inflammation (two).	7645111
CLU protein, human, Inflammation, Impaired	Altered Intercellular Communication	The role of blood changes associated with inflammation and/or nutrition in this relative impairment is supported by the positive correlations that we observed between CLI and acute-phase proteins.	7645447
Impaired	Altered Intercellular Communication	This observation suggests a relative impairment in EP phagocytic adaptive responses to inflammatory conditions.	7645447
Communicable Diseases, Inflammation	Altered Intercellular Communication	The key to surgical success is undoubtedly a careful preoperative treatment of infection and inflammation as well as a meticulous muco-mucosal approximation of healthy margins at the anastomosis.	7646083
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	Six patients (7.1% of positive nodes) had a metastasis of unknown primary site, and 19 cases (19.8%) had acute or chronic inflammation; seven of the latter cases demonstrated acid-fast bacilli in the aspirated smears.	7646330
Edema, Meningitis	Altered Intercellular Communication	The Gd infusion showed enhancement in cysts with adjacent inflammatory reaction or edema and in cases with meningeal inflammation.	7650528
Inflammation	Altered Intercellular Communication	However, the results did not allow a differentiation between chronic and acute inflammation.	7652465
Inflammation, Carcinoma of lung	Altered Intercellular Communication	In two more cases the diagnosis of lung cancer made by computer-aided biopsy was erroneous because of the presence of inflammation elements and amorphous mass in the examined.	7653048
Carcinoma of lung, Neoplasms	Altered Intercellular Communication	Biopsies proved to be informative in 44 out of 48 patients with lung cancer, in 8 out of 10 ones with benign tumors, and in 10 out of 12 ones with nonspecific inflammations.	7653048
Uveitis	Altered Intercellular Communication	A low rate of postoperative intraocular inflammation was observed in our patients receiving phacoemulsification with heparin infusion solution (slit-lamp examination).	7655202
Inflammation, Peripheral lymphadenopathy, Fever, CTCAE, Lymphoma, Hodgkin Disease, Pruritus	Altered Intercellular Communication	A number of clinical features (young male, nocturnal sweats, generalized pruritus, protracted fever, central or peripheral lymphadenopathy) and laboratory test abnormalities (evidence of severe inflammation) considerably increased the likelihood of Hodgkin's disease rather than malignant lymphoma.	7655870
Inflammation, Corneal Diseases	Altered Intercellular Communication	The authors sought to determine if corneal diseases with different patterns of inflammation are accompanied by characteristic patterns of cytokine expression.	7657553
Synoviocytes, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	A repeated histological examination of the synovial membrane of 14 joints in which good results were obtained disclosed a reduction in inflammation and transitory synovial cell hyperplasia that ended in a dense fibrosis.	7659899
Inflammation, Gangrene	Altered Intercellular Communication	In the fourth patient the procedure was converted to an open cholecystectomy because of extensive inflammation surrounding a gangrenous gallbladder.	7660264
Inflammatory Bowel Diseases, Inflammation, Thrombosis, Thrombophilia, Abnormality of coagulation	Altered Intercellular Communication	The mechanisms of the increased risk of thrombosis are not well understood: although several coagulation abnormalities have been described in inflammatory bowel disease patients, it is not clear whether they actually contribute to hypercoagulation or whether they are nonspecific markers of inflammation.	7661181
Spinocerebellar Ataxia Type 7, Inflammation, Retinal pigment epitheliitis	Altered Intercellular Communication	The pigmentary maculopathy of acute retinal pigment epitheliitis may be secondary to primary inflammation of the neurosensory retina.	7661213
Presenile dementia	Altered Intercellular Communication	These findings suggest that the VEPs abnormality elicited by large checks is related to dementia independent of progression of the illness, and that a nondopaminergic neurotransmitter system may play a role in the development of VEPs delay elicited by large checks.	7662325
Necrotizing granulomatous inflammation, Abscess	Altered Intercellular Communication	Histopathology of a resected nodule demonstrated neutrophilic granulomatous inflammation with central abscess formation.	7663655
Gastrointestinal inflammation	Altered Intercellular Communication	Our results demonstrate that chronic intestinal inflammation in patients with CD is characterized by an increase of Th1-like cytokines.	7664489
Pulmonary failure, Cessation of life	Altered Intercellular Communication	CFA is an inflammatory condition of the lungs resulting in scarring, pulmonary failure and death.	7664490
Axonal degeneration, Inflammation	Altered Intercellular Communication	Microscopic findings of the left sural nerve biopsy showed a primary axonal degeneration without evidence of inflammation.	7664519
Inflammation, Demyelination, MS gene	Altered Intercellular Communication	Her clinical features resembled multiple sclerosis, but magnetic resonance imaging (MRI) of the brain and spinal cord revealed no evidence of demyelination or inflammation.	7664520
Necrotizing granulomatous inflammation, Diphtheria Toxin	Altered Intercellular Communication	Histopathological examination showed granulomatous necrotizing inflammation with growth of Corynebacterium ulcerans, which did not produce diphtheria toxin.	7664868
Inflammation, Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Chronic gastritis was seen in 76% of the patients taking NSAID and in 58% of the control cases; active inflammation was detected in 10% of the NSAID treated patients and in 24% of the control cases, and it appeared closely related with Helicobacter pylori infection.	7665699
Hepatitis	Altered Intercellular Communication	Patients with severe liver inflammation had high-density hepatitis C virus that did not precipitate with anti-immunoglobulins but with anti-core hepatitis C virus antibodies.	7665862
Inflammation, Hepatobiliary Disorder	Altered Intercellular Communication	Therefore, the major hepatitis C virus populations change from virion to immune complex and/or nucleocapsid with the progression of liver disease or inflammation.	7665862
Communicable Diseases, Nephritis, Neoplastic disease	Altered Intercellular Communication	To examine this discrepancy, erythrokinetic studies were made of 22 hematologically stable dialysis patients without clinical or laboratory evidence of extrarenal inflammation, infection, or neoplastic disorders.	7665976
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	Eicosanoids and cytokines produced by alveolar macrophages (AM) are key mediators of pulmonary inflammation and fibrosis.	7666496
Airway structure	Altered Intercellular Communication	The condition has a heritable component and is closely related to serum IgE levels and airway inflammation.	7666875
Hypokalemia	Altered Intercellular Communication	Our findings suggest that intermittent hypokalemia is a sign of drifting hormonal activities and may appear in a premature status of pre-Cushing's syndrome.	7668184
Inflammation	Altered Intercellular Communication	Such observations add weight to the concept that MCs contribute to the processes of inflammation, matrix degradation and tissue remodelling.	7668897
Inflammation	Altered Intercellular Communication	The clinical syndrome is a severe, painful inflammation of the external auditory canal with edematous obstruction of the external canal and typical granulation tissue in the canal wall.	7669139
Pain Distress Question	Altered Intercellular Communication	Substance P has been implicated as a mediator of pain, and depletion of this neurotransmitter has been shown to reduce pain.	7670427
Sarcoma, Inflammation	Altered Intercellular Communication	Radiographic images, ultrasound, and magnetic resonance imaging of the forearm could not distinguish inflammation from sarcoma.	7671483
Choroidal Detachment, Inflammation, Intraoperative Hemorrhage, Failure, functional failure	Altered Intercellular Communication	We identified extensive detachment, preoperative choroidal detachment, intraoperative hemorrhage and surgery for PVR as predictors of anatomic failure, while preoperative inflammation, preoperative PVR of grade B or worse, and surgery for PVR were predictors of functional failure.	7672618
pancolitis, Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	Histological examination showed a mild superficial pancolitis, with focal severe inflammation, deep fissuring ulceration, and pseudopolyposis.	7672667
Inflammation, Pseudotumor, Bronchogenic Carcinoma	Altered Intercellular Communication	The authors herein report three examples of sarcomatoid bronchogenic carcinoma with a deceptively bland appearance and an investment of reactive inflammation, such that they resembled pseudotumors histologically.	7672783
Cataract, Inflammation	Altered Intercellular Communication	In conclusion, diclofenac sodium was shown to be clinically useful as a topical preparation to suppress inflammation after cataract surgery.	7674169
Inflammation, Osteopenia	Altered Intercellular Communication	Inflammation was noted around 70% of the implants, and marginal bone loss around 13% of the implants exceeded 2 mm.	7674192
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	In situ studies colocalized tissue MMP-2 and TIMP-2 expression to VSMCs and macrophages surrounding inflammation in aneurysmal adventita, but to atherosclerotic plaque in occlusive aorta.	7674473
Gastritis	Altered Intercellular Communication	Elevated gastric 201Tl uptake may be a clinically useful finding indicative of gastric inflammation that may be of value in the differential diagnosis of chest and epigastric discomfort.	7675361
Inflammation	Altered Intercellular Communication	The pathogenesis of this uncommon occurrence of two amyloids and the role of chronic inflammation in amyloidogenesis are discussed.	7675780
Ischemia, Inflammation	Altered Intercellular Communication	RVP should, therefore, be considered as the last resort in the treatment of critical ischemia and/or inflammation of the leg of patients facing possible amputation.	7676739
Meningitis	Altered Intercellular Communication	A significant correlation with SIADH was observed in cases with evidence of severe meningeal inflammation (p < 0.001).	7677422
Arthritis	Altered Intercellular Communication	These observations suggest that increased resting IAP is a marker for chronic joint inflammation.	7677444
Osteomyelitis, Inflammation	Altered Intercellular Communication	The RM3/1-positive macrophage associated with the down-regulation of inflammation was detectable to a low extent in 4/13 evaluable biopsies from the osteomyelitis focus before the start of therapy.	7696053
Pain Distress Question, Inflammation	Altered Intercellular Communication	Both types were mainly prescribed to relieve pain and reduce inflammation.	7697955
Autoimmune Chronic Hepatitis, Hepatitis, Insemination, Artificial, Homologous	Altered Intercellular Communication	Autoimmune hepatitis (AIH), an unresolving liver inflammation characterized by periportal hepatitis and presence of serum autoantibodies, is distinguished by smooth muscle antibody and/or antinuclear antibody seropositivity.	7698584
Granulomatous inflammation, Crohn Disease	Altered Intercellular Communication	The pancreas as a site of granulomatous inflammation in Crohn's disease.	7698591
Granulomatous inflammation, Crohn Disease	Altered Intercellular Communication	Histological examination showed a granulomatous inflammation caused by Crohn's disease involving the stomach, the duodenum, and the head of the pancreas, clearly showing that the pancreas can also be a localization of Crohn's disease.	7698591
Granulomatous inflammation, physiopathological, Crohn Disease	Altered Intercellular Communication	Granulomatous inflammation could be an important factor in the pathogenesis of pancreatic dysfunction occurring in association with Crohn's disease.	7698591
Inflammation, Bone necrosis, Facial Pain	Altered Intercellular Communication	Thirty percent, however, experienced local recurrence of jaw inflammation and facial pain, and one third developed at least one and as many as 12 additional foci of histologically confirmed osteonecrosis.	7699492
Pneumonitis	Altered Intercellular Communication	[The ultrastructure of the neutrophilic leukocytes and alveolar macrophages in chronic lung inflammation and in endobronchial laser irradiation].	7701622
Inflammation	Altered Intercellular Communication	Twenty four specimens of fresh synovial tissue were obtained from patients undergoing primary total knee joint replacement and graded according to the degree of inflammation present.	7702413
Morbidity - disease rate, Ocular Cicatricial Pemphigoid, Conjunctivitis	Altered Intercellular Communication	Ocular cicatricial pemphigoid (OCP) can present with severe conjunctival inflammation that requires systemic immunosuppression to avoid serious ocular morbidity.	7703207
Inflammatory abnormality of the eye	Altered Intercellular Communication	The ocular inflammation resolved in 15 eyes in a mean time of 2.4 months.	7703207
Inflammation	Altered Intercellular Communication	Cyclophosphamide and short term, high dose prednisolone are effective in severe inflammation caused by OCP but may not completely prevent cicatrisation.	7703207
Inflammation, Failure (biologic function)	Altered Intercellular Communication	None of the clinical parameters at surgery except rectal inflammation influenced the outcome: patients showing moderate or severe inflammation in the rectum at surgery had a higher failure rate than those with mild or no inflammation (p < 0.02).	7703514
Gingivitis, Calculi, Dental Plaque	Altered Intercellular Communication	Sites which subsequently progressed had significantly more plaque, subgingival calculus and gingival inflammation than non-progressing sites at the baseline examination and throughout the study (p < 0.001).	7706535
Inflammation, Neoplasms	Altered Intercellular Communication	We present an unusual case where the appearance of a tumour was the result of chronic inflammation stimulated by the presence of food matter.	7706922
Pain Distress Question, Sinusitis	Altered Intercellular Communication	The nasal specific technique, when used in conjunction with other therapies, may be useful in treating chronic sinus inflammation and pain.	7706959
Inflammation	Altered Intercellular Communication	Inflammation in some joints declined, the articular index decreased.	7709352
Acute inflammation	Altered Intercellular Communication	Stenosis with acute inflammation can be treated by anti-inflammatory medication.	7709702
Inflammation, Renal Pelvis Fistula	Altered Intercellular Communication	Early morbidity primarily involves pelvic or parietal infectious problems, while late complications comprise pelvic fistulae, obstructive events, and episodes of pouch inflammation.	7709703
Intraocular Route of Drug Administration, Neoplasm Metastasis	Altered Intercellular Communication	Iris metastasis can show a spectrum of clinical variations, but its features are generally distinctive enough to differentiate it from other intraocular neoplasms and inflammations.	7709967
Retinal Detachment, Inflammation, Visual Impairment, Endophthalmitis	Altered Intercellular Communication	Five weeks after the injury and one week after the vitrectomy, sympathetic ophthalmia developed, with severe visual impairment and inflammation and serous retinal detachment in the fellow eye.	7709973
Retinal Detachment, Inflammation	Altered Intercellular Communication	There was clinical remission of inflammation and absorption of exudative retinal detachment.	7709973
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Eicosanoids act obviously as mediators of inflammation in ulcerative colitis.	7712517
Rheumatoid Arthritis, Graft-vs-Host Disease, Dryness (characteristic)	Altered Intercellular Communication	Both patients had severe dry eyes, case 1 secondary to graft-versus-host disease and case 2 secondary to rheumatoid arthritis, and a persistent epithelial defect and anterior segment chronic inflammation.	7712745
Inflammation, Gastro-esophageal reflux disease with esophagitis, Esophageal, Fibrosis Assessment, Acid reflux	Altered Intercellular Communication	Precise staging of reflux esophagitis is very important for therapeutic decisions; in fact, chronic gastroesophageal reflux may cause transmural inflammation that leads to fibrosis with loss of esophageal wall compliance.	7712992
Inflammation, Gastro-esophageal reflux disease with esophagitis	Altered Intercellular Communication	In conclusion, EUS seems to be an important supplement to endoscopy in staging reflux esophagitis, as the progression of the inflammation is not related to the endoscopic findings.	7712992
Inflammation, Acute necrotizing inflammation	Altered Intercellular Communication	In five autopsy cases, the inflammation was usually a focal or diffuse, acute necrotising inflammation with varying numbers of neutrophils, macrophages, lymphocytes and 'giant cells'.	7713483
Inflammation	Altered Intercellular Communication	In 14 surgical cases biopsies showed acute inflammatory lesions that appeared no different from acute inflammation due to other causes.	7713483
Inflammation, Acute and chronic inflammation	Altered Intercellular Communication	In many biopsies, however, the inflammation was either an acute-on-chronic inflammation with a focal granulomatous component, or was purely granulomatous in character.	7713483
Inflammation, Neoplasms	Altered Intercellular Communication	The remaining diseases were orbital inflammations and tumours, and their numbers were similar.	7716938
Inflammation, Orbital Neoplasms	Altered Intercellular Communication	The fact is worth attention of decreasing number of orbital inflammations in successive years and increasing tendency for orbital tumour occurrence.	7716938
Inflammation, Coronary Artery Disease, Fibrinogen in blood above reference range	Altered Intercellular Communication	Hyperfibrinogenemia and relative leucocytosis correlate with the angiographic and clinical extent of coronary artery disease and may offer evidence of a higher degree of thrombogenesis associated with components of inflammation.	7717023
Mesenteric Panniculitis, Inflammation	Altered Intercellular Communication	Mesenteric panniculitis is a rare process in which there is an inflammation of the mesenteric adipose tissue due to unknown causes and mechanisms.	7718718
Congenital laryngeal abductor palsy, Paralysed	Altered Intercellular Communication	This is the first report on a case of syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with Gerhardt syndrome (paralysis of bilateral vocal cords).	7718959
Inflammation, Sinusitis	Altered Intercellular Communication	On the basis of the histamine and PGD2 concentrations in sinus fluid, we conclude that mast cell/basophil activation does occur in chronic sinusitis and may contribute to the persistent inflammation present in sinusitis.	7719157
Inflammation, Thrombosis of subclavian vein	Altered Intercellular Communication	The major complications were pinch-off sign observed in 5 patients, inflammation in 6 patients (4.2%), and subclavian vein thrombosis in 7 patients, and other miscellaneous complications in 7 patients.	7719163
Inflammation, Specimen Type - Fistula	Altered Intercellular Communication	The apparent mechanisms of fistula formation include inflammation of the gallbladder, its subsequent fusion to the bile duct, and increase in the internal pressure due to either contraction of the gallbladder or multiple stones.	7719405
Inflammation, Asthma	Altered Intercellular Communication	Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation.	7722165
Airway structure, Asthma, Cystic Fibrosis, mucus secretion	Altered Intercellular Communication	To infer possible mechanisms of acute airway inflammation and mucus hypersecretion in acute severe asthma, we performed cellular and biochemical analysis on sputum from 18 adults with acute severe asthma and compared the results with results of analysis of sputum from 12 adults with cystic fibrosis (CF).	7722165
Sicca Syndrome, Chronic inflammation	Altered Intercellular Communication	The patient suffered of a sicca syndrome with chronic inflammation of the conjunctiva.	7722240
Diversion procedure, Inflammation	Altered Intercellular Communication	Fistulization was associated with a repeat chronic inflammation and metastatic carcinomatous infiltration.	7724001
Conjunctival cicatrization, Congenital Abnormality, Ocular Cicatricial Pemphigoid, Stevens-Johnson Syndrome, CTCAE, Dryness of eye, Corneal Neovascularization, Conjunctivitis	Altered Intercellular Communication	The outcome of successful penetrating keratoplasty (PK) typically is poor in eyes with end-stage chronic cicatrizing conjunctival diseases such as ocular cicatricial pemphigoid (OCP), Stevens-Johnson syndrome, and toxic epidermal necrolysis due to immunologically driven conjunctival inflammation associated with conjunctival cicatrization and lid abnormalities, severe dry eye, and extensive corneal neovascularization.	7724175
Inflammation, Arthritis	Altered Intercellular Communication	As the available in vitro and in vivo data suggest that interleukin (IL)-4 and IL-10 have immunosuppressive activity, our hypothesis was that serum IL-4 and IL-10 levels would correlate inversely with parameters of inflammation in patients with inflammatory arthritis.	7724996
Muscle Rigidity, Pain Distress Question, Inflammation	Altered Intercellular Communication	Logistic regression analysis of 23 parameters identified the following data as associated with a higher risk for conversion: pain or rigidity in the right upper abdomen (P < 0.01), thickening of the gallbladder wall on preoperative ultrasound (P < 0.05), intraoperatively found dense adhesions to the gallbladder or in Calot's triangle (P < 0.001), and intraoperatively found acute inflammation of the gallbladder (P < 0.01).	7725209
Inflammation, Necrotizing vasculitis, Cutaneous Small Vessel Vasculitis, Capillaritis	Altered Intercellular Communication	Classic necrotizing granulomatous inflammation and necrotizing vasculitis were the most common findings, although other variants were occasionally encountered, including the eosinophilic variant (two cases), the bronchocentric variant (one case), and small-vessel vasculitis and capillaritis (one case).	7726364
Mesenteric Panniculitis, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Mesenteric panniculitis is an infrequent pathology; the diagnosis is made by the pathologist and it is characterized by inflammation, fibrosis and retraction of the mesenteric fat.	7727170
Crohn Disease, physiopathological	Altered Intercellular Communication	Crohn's disease associated with growth hormone secretory dysfunction.	7727875
physiopathological	Altered Intercellular Communication	Endocrinologic examination indicated growth hormone (GH) secretory dysfunction.	7727875
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	We have examined the hypothesis that interferon-gamma (IFN-gamma) and its interaction with epithelium may play a role in the perpetuation of inflammation in Sjogren's syndrome (SS).	7728396
Inflammation, PEELING SKIN SYNDROME	Altered Intercellular Communication	These findings suggest that the perpetuation of chronic inflammation of pSS may be due to the induction of HLA-DR and La antigen expression on epithelial cells by IFN-gamma.	7728396
Aggressive course	Altered Intercellular Communication	Our results indicate that up-regulation of sialyl LewisX is associated with hormonal-resistant, aggressive disease.	7728744
Inflammation, Granuloma	Altered Intercellular Communication	Mucosal biopsy specimens showed only mild nonspecific chronic inflammation of the lamina propria and no granulomas.	7729648
Inflammation, Dental Plaque	Altered Intercellular Communication	Plaque samples were taken from the adjacent tooth surface and from a second posterior site where the adjacent gingiva was free of signs of inflammation.	7730969
Gingivitis, Inflammation, Dental Plaque	Altered Intercellular Communication	Isolation frequency and numbers of mycoplasmas in relation to total anaerobic counts were consistently related to gingivitis scores in both plaque and saliva samples, with higher frequencies and proportions with increasing levels of gingival inflammation at the selected site.	7730969
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	H&E-stained liver sections were reviewed independently to determine the presence and extent of inflammation, fibrosis, and necrosis.	7731944
Idiopathic disease, Eosinophilic gastroenteritis, Inflammation	Altered Intercellular Communication	Eosinophilic gastroenteropathy is an uncommon, idiopathic disease in children that is characterized by eosinophilic inflammation of the intestine.	7732607
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Fibrosis and inflammation were evaluated by hematoxylin and eosin and by trichrome stains.	7732786
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The variables, fibrosis, and inflammation, did not demonstrate prognostic significance (P > 0.05).	7732786
Inflammation, Membranous vitreous appearance	Altered Intercellular Communication	[Anterior chamber inflammation after vitrectomy in posterior vitreous membrane syndrome and phacoemulsification and intraocular lens implantation].	7732926
Intraocular inflammation	Altered Intercellular Communication	Clinicopathologic study of retinal and choroidal biopsies in intraocular inflammation.	7733185
Inflammation, Fibrosis Assessment, Candida (fungus)	Altered Intercellular Communication	The remaining five endoretinal biopsies disclosed Candida in one specimen, subretinal fibrosis in one, and chronic inflammation in three.	7733185
Chorioretinitis, Inflammation, Viral retinitis, Chorioretinal scar, Lymphoma	Altered Intercellular Communication	Histologic examination of the nine chorioretinal or choroidal biopsies disclosed lymphoma in two specimens, a subretinal neovascular membrane in one, uveal melanocytic proliferation in one, toxoplasmic retinochoroiditis in one, viral retinitis in one, and long-standing inflammation in three.	7733185
Intraocular inflammation	Altered Intercellular Communication	In select cases of intraocular inflammation, intraocular tissue biopsies may provide clinically useful information.	7733185
Meningitis	Altered Intercellular Communication	Lumbar puncture disclosed increased intracranial pressure and sterile meningeal inflammation.	7733200
Communicable Diseases, Inflammation, congenital obstruction	Altered Intercellular Communication	Acute infection and inflammation of the nasolacrimal sac may complicate congenital obstruction of the nasolacrimal duct.	7735447
Airway structure, Asthma	Altered Intercellular Communication	A role for diet in the pathophysiology of asthma may be mediated by altered immune or antioxidant activity with consequent effects on airway inflammation.	7735592
Inflammation	Altered Intercellular Communication	Adhesion molecules play a critical role in the interaction of circulating neutrophils with vascular endothelium during inflammation.	7735595
Inflammation, immunoglobulin A	Altered Intercellular Communication	The number of IgG and IgA antibody-producing cells was positively correlated with the degree of inflammation of the gastric mucosa.	7735943
Interstitial inflammation	Altered Intercellular Communication	Lung biopsies were performed on two patients showing a pattern of interstitial inflammation.	7736401
Inflammation	Altered Intercellular Communication	Sulphonamides as anti-inflammatory agents: old drugs for new therapeutic strategies in neutrophilic inflammation?	7736703
Tissue injury	Altered Intercellular Communication	They can also be viewed as a previously unrecognized starting point for the development of new compounds in order to plan rational therapeutic strategies for controlling tissue injury during neutrophilic inflammation.	7736703
Tumor necrosis, Inflammation, Heart failure	Altered Intercellular Communication	Tumor necrosis factor, natural killer activity and other measures of immune function and inflammation in elderly men with heart failure.	7737534
Tumor necrosis, Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	To determine the status of tumor necrosis factor (TNF) and other measures of immunity and inflammation in chronic heart failure (CHF) in the elderly.	7737534
Inflammation, Heart failure	Altered Intercellular Communication	TNF and other measures of immune function and inflammation do not appear to be significantly elevated in elderly patients with heart failure of moderate severity.	7737534
Inflammation, Heart failure	Altered Intercellular Communication	However, significant relationships exist between TNF, NK activity, XDP and E/alpha in the heart failure patients only, suggesting that immune activation and subclinical inflammation does exist in these patients.	7737534
Inflammation, Hepatitis C	Altered Intercellular Communication	Serum ICAM-1 levels were significantly higher in patients with chronic hepatitis C infection than in normal subjects and correlated positively with the grade of histological activity, in particular the degree of portal, periportal, and lobular inflammation, but not with the presence of lymphoid aggregates.	7737571
Inflammation, Hemorrhage	Altered Intercellular Communication	Complete aspiration of gallbladder bile could be achieved in all patients without complications such as bleeding, bile leak, or inflammation.	7737635
Arthralgia, Hypertrophic osteoarthropathy, Malignant neoplasm of lung, Pulmonary Sulcus Neoplasm	Altered Intercellular Communication	After chemoradiotherapy for pulmonary cancer, the arthralgia disappeared and scintigraphic findings and serum growth hormone levels improved, suggesting that ectopic production of growth hormone in the pulmonary tumor had been associated with hypertrophic osteoarthropathy.	7738658
Mirizzi Syndrome, Hypertension, CTCAE, Liver Cirrhosis	Altered Intercellular Communication	The indications were severe inflammation/fibrosis in 3 patients, cirrhosis with mild portal hypertension in 1 patient and the Mirizzi syndrome in the last patient.	7738890
Extrinsic allergic alveolitis, Inflammation, Idiopathic pulmonary hemosiderosis, Sarcoidosis, Pulmonary Emphysema, Pulmonary Fibrosis, Hamman-Rich syndrome	Altered Intercellular Communication	A tissue diagnosis was obtained in all patients: 8 had cryptogenic fibrosing alveolitis, 3 had interstitial pulmonary fibrosis, 2 had emphysema, 2 had extrinsic allergic alveolitis, 2 had sarcoidosis, 1 had non-specific chronic inflammation, and 1 had pulmonary haemosiderosis.	7738891
Ischemia, vascular inflammations, Vascular occlusion	Altered Intercellular Communication	This case is important in that vascular occlusion and ischemia progressed soon after vascular inflammation was relieved by administration of corticosteroid hormone.	7739175
Ischemia, vascular inflammations, Vascular occlusion	Altered Intercellular Communication	This case is important in that vascular occlusion and ischemia progressed soon after vascular inflammation was relieved by administration of corticosteroid hormone.	7739175
Somatotropin deficiency	Altered Intercellular Communication	Growth hormone deficiency (GHD) associated with and secondary to asphyxiating perinatal events is a well-established disorder of childhood.	7740630
Anemia, Inflammatory disorder	Altered Intercellular Communication	This study suggests blunted erythropoietin production and impaired marrow response to this hormone in the anaemia which occurs in inflammatory syndromes and supports the hypothesis that these disorders may contribute to the development of the anaemia associated with inflammatory disorders.	7741403
Inflammation	Altered Intercellular Communication	Microscopic examination of material obtained by punch, core needle, and incisional biopsies demonstrated nonspecific acute and chronic inflammation.	7741445
Airway structure, Inflammation	Altered Intercellular Communication	Only 4.4% (27) knew that steroids decrease airway swelling or inflammation.	7741500
Acute myocardial infarction, Inflammation	Altered Intercellular Communication	Whether and to what extent complement is activated in acute myocardial infarction (AMI) and how it contributes to inflammation of the ischemic area are not yet clear.	7741820
Inflammation, Hemorrhage, Necrosis	Altered Intercellular Communication	Necroses, extensive hemorrhages or inflammation were not found.	7741840
Inflammation, Blood coagulation, Cardiovascular system	Altered Intercellular Communication	We suggest that such ultra-fine particles are able to provoke alveolar inflammation, with release of mediators capable, in susceptible individuals, of causing exacerbations of lung disease and of increasing blood coagulability, thus also explaining the observed increases in cardiovascular deaths associated with urban pollution episodes.	7741860
Intraocular inflammation	Altered Intercellular Communication	We propose that if pilocarpine does indeed diminish corneal allograft immune privilege and enhance graft rejection, the mechanisms may include induced intraocular inflammation and altering of anterior chamber associated immune deviation.	7743805
Communicable Diseases, Intraocular inflammation	Altered Intercellular Communication	The infection was quiescent for the subsequent 12-month period until recurrent intraocular inflammation developed with enlargement of the endothelial plaque.	7743808
Inflammation, Tuberculosis, Pulmonary	Altered Intercellular Communication	However, the sIL-2R levels were still higher than control subjects at completion of treatment, suggesting a delayed resolution of the inflammation in patients with pulmonary TB.	7744196
Granuloma, Foreign-Body	Altered Intercellular Communication	A 60-year-old woman had extensive and recurrent foreign-body granulomatous inflammation of her forehead.	7748079
Inflammation, Hepatic duct injury, Distortion	Altered Intercellular Communication	Six (67%) of these patients required conversion to open procedures (two for common bile duct exploration, one for repair of a common hepatic duct injury, and three for anatomic distortion due to inflammation).	7748087
Chorioretinal scar, Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Poor visual acuity was associated with glaucoma, chorioretinal scars in the macula, and persistent uncontrolled inflammation.	7748129
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Patients with rheumatoid arthritis (RA) have defective hypothalamic responses to inflammation, possibly because of excessive production of cytokine inhibitor, which could blunt the effects of cytokines on the hypothalamus, or because of an imbalance between interleukin-1 beta (IL-1 beta) and interleukin-1 receptor antagonist (IL-1Ra), which could create a mainly proinflammatory state.	7748221
Inflammation, Edema	Altered Intercellular Communication	It was confirmed by histological examination that the MRI findings indicated the presence of inflammation and oedema in the vertebral bone marrow.	7749909
Inflammation, Fracture, Compression fracture of vertebral column	Altered Intercellular Communication	We postulate that after fracture healing and subsidence of inflammation, the Schmorl's nodes become asymptomatic, in analogy with old vertebral compression fractures.	7749909
Coughing, Asthma, Airway structure	Altered Intercellular Communication	Chronic cough associated with eosinophilic airway inflammation can occur in the absence of variable airflow obstruction (asthma) and can improve after treatment with inhaled corticosteroid.	7750004
Inflammation, Hemorrhage, Neoplasms	Altered Intercellular Communication	Retrospective review of CT scans for 42 patients who had abnormalities of the iliopsoas compartment revealed that inflammation was responsible in 20, hemorrhage in 8, and tumor in 14 patients.	7750059
Crohn Disease	Altered Intercellular Communication	Metastatic Crohn's disease is a rare inflammatory condition characterised by cutaneous granulomatous lesions separated from the affected bowel by normal intact skin.	7750954
Nephritis, Interstitial, Injury of liver, Xerostomia, Sialadenitis	Altered Intercellular Communication	In two patients liver injury was accompanied by prominent extrahepatic manifestations (acute interstitial nephritis in one and acute lacrimal gland inflammation and sialadenitis with prolonged xerostomia in the other).	7751590
Neoplasms	Altered Intercellular Communication	Increased binding was not markedly due to up-regulation of the inflammation-induced endothelial cell adhesion molecules in tumors, because binding to inflamed synovium that expressed the same adhesion molecules was not enhanced.	7751643
Inflammation, Arthritis	Altered Intercellular Communication	One fourth of the rheumatic complaints was caused by inflammation (21% arthritis, 5% sacroileitis).	7752802
Inflammation	Altered Intercellular Communication	Expression of mRNA for vasoactive intestinal peptide in normal human colon and during inflammation.	7753037
Ulcerative Colitis	Altered Intercellular Communication	In previous work, we identified decreased tissue levels of vasoactive intestinal peptide in a disorder of chronic colonic mucosal inflammation, ulcerative colitis.	7753037
Chronic inflammation	Altered Intercellular Communication	These observations suggest that decreased vasoactive intestinal peptide gene expression or abnormal post-transcriptional processing are not primary defects in this disorder of chronic inflammation.	7753037
Spinal Cord Injuries	Altered Intercellular Communication	Chronic cervical spinal cord injury is characterized by defects in sodium and water homeostasis and defects of adaptive hormonal responses.	7753575
Fibrosis Assessment, Lymphoma, Follicular	Altered Intercellular Communication	Follicular lymphoma adjacent to foreign body granulomatous inflammation and fibrosis surrounding silicone breast prosthesis.	7755157
Klinefelter Syndrome, Endocrine System Diseases	Altered Intercellular Communication	Presumably, in Klinefelter's syndrome both alterations--of prolactin and thyrotrophin secretion--may be caused by decrease of testosterone levels or they could reflect a disturbance in neuroendocrine regulation with some neurotransmitter imbalance.	7755189
Gastritis, Peptic Esophagitis	Altered Intercellular Communication	The efficacy and safety of the proteolytic enzyme inhibitor FUT-187 were evaluated in postgastrectomy reflux esophagitis and gastric remnant inflammation.	7755385
Gastritis, Peptic Esophagitis	Altered Intercellular Communication	The subjects consisted of 4 patients with postgastrectomy reflux esophagitis and 9 patients with gastric remnant inflammation.	7755385
Gastritis, Peptic Esophagitis, Ulcer	Altered Intercellular Communication	In the endoscopic classification of lesions, postgastrectomy reflux esophagitis was classified as erosive or ulcerative and gastric remnant inflammation as superficial.	7755385
Gastritis, Peptic Esophagitis	Altered Intercellular Communication	Based on the results of this study, it may be concluded that FUT-187 is an effective drug with a wide margin of safety for postgastrectomy reflux esophagitis and gastric remnant inflammation.	7755385
Inflammation, Rheumatic Fever, Celiac Disease, Intestinal Diseases, Polyarthropathy	Altered Intercellular Communication	It is known that joint inflammation occurs in certain patients with adult coeliac sprue who develop either a specific inflammatory rheumatic disease or an atypical progressive polyarthropathy, sometimes as the first manifestation of the intestinal disorder.	7761362
Infarction, Inflammation	Altered Intercellular Communication	There were false-positive diagnoses in 5% with FNAB of the lung due to misinterpretation of regenerating epithelium and hamartochondroma and a 0.1% rate of false-negative diagnoses as a result of misplacement of the cannula, leading to inflammation, infarction or scarring.	7762333
Abdominal Infection, Inflammation, Biliary calculi	Altered Intercellular Communication	We report three instances of delayed intra-abdominal infection and/or inflammation related to these misplaced gallstones.	7763177
Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	HGF mRNA levels in patients with H. pylori infection were correlated with the severity of gastric mucosal inflammation.	7763269
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In diseases such as cystic fibrosis (CF) that may be candidates for integrative gene therapy, airway cell turnover is not known but may be increased as a result of chronic inflammation.	7766425
Granuloma, Inflammation, Papilloma	Altered Intercellular Communication	Twelve patients undergoing excisional biopsy or lumpectomy of breast resulted in 7 fibroadenomas, 2 papillomas, 1 abscess, 1 granuloma and 1 chronic inflammation.	7770238
Inflammation, Hyperplasia, Papilloma	Altered Intercellular Communication	The patients with absence of MIBI uptake included 3 fibroadenomas, 2 papillomas, 1 abscess, 1 chronic inflammation and 17 fibrous hyperplasia.	7770238
Inflammation, Endocrine System Diseases, Amyloidosis, Bronchitis, Histogenic Process	Altered Intercellular Communication	Its histogenesis is not clear and is attributed to chronic bronchitis, specific inflammation, dysembryogenetic alterations, endocrine disorders, environmental and occupational hazards, amyloidosis of the trachea.	7771928
Inflammation, Carcinoid Tumor	Altered Intercellular Communication	3 carcinoids, 3 tuberculoses, 1 non-specific inflammation.	7771931
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Crypt	Altered Intercellular Communication	We investigated 209 consecutive series of biopsies taken from 38 patients with UC, 12 with CD, and 105 with other colitides, to evaluate whether combinations of histological features, selected on the basis of our experience, and listed below, could be useful criteria for the differential diagnosis of IBD, and, more specifically, of UC: (A) chronic inflammation with a predominant increase of plasma cells, (B) crypt distortion, (C) crypt atrophy, (D) diffuse chronic inflammation within a biopsy and between biopsies, and (E) diffuse mucin depletion within a biopsy and between biopsies.	7773349
Inflammation, Edema, Rupture	Altered Intercellular Communication	In the right clinical setting, CT findings of inflammation or edema surrounding the oleothorax rupture may warrant surgical intervention.	7773876
Inflammation, Fever, CTCAE, Urticaria, Lymphoproliferative Disorders, dysproteinemia	Altered Intercellular Communication	Schnitzler's syndrome, first described in 1974, is defined by chronic non-pruritic urticaria, osteocondensation, and monoclonal IgM dysproteinemia without features of lymphoproliferative disease, and is associated with fever, deterioration of the general health and biological signs of inflammation.	7774112
Inflammation, Hypersensitivity	Altered Intercellular Communication	This hypersensitivity is counteracted, possibly at the site of inflammation, by high local concentrations of cytokines.	7775626
Inflammation	Altered Intercellular Communication	From a clinical perspective, these results suggest that elevated levels of PGE2 associated with inflammation will attenuate an IgG response and, as PGE2 production wanes, the local humoral response will rebound.	7776168
Pain Distress Question, Inflammatory abnormality of the eye	Altered Intercellular Communication	Response to therapy was determined by subjective improvement in pain and a decrease in clinical signs of ocular inflammation.	7777270
Inflammation	Altered Intercellular Communication	Mucociliary function of chronic inflammation in upper and lower airways.	7779023
Inflammation	Altered Intercellular Communication	Mucociliary function was examined to investigate the association of chronic inflammation in the upper and lower airways in four groups of subjects.	7779023
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Influence of intestinal inflammation (IBD) and small and large bowel length on fecal short-chain fatty acids and lactate.	7781463
Inflammation, Crohn Disease	Altered Intercellular Communication	We conclude that the site of inflammation and the healing capacity of the epithelium are important in determining functional and biochemical abnormalities in active Crohn's disease.	7781465
Inflammation	Altered Intercellular Communication	Salivary PAF levels correlate with the severity of periodontal inflammation.	7782535
Inflammation, Metrorrhagia	Altered Intercellular Communication	Significant positive correlations were observed between the level of PAF in saliva and measures of periodontal inflammation, i.e., the percentage of periodontal probing depths greater than 4 mm, the number of periodontal bleeding sites, and the number of histologically identified polymorphonuclear neutrophilic leukocytes (PMN) in saliva.	7782535
Inflammation	Altered Intercellular Communication	Thus, salivary PAF levels correlate with the severity of periodontal inflammation.	7782535
Inflammation, Pansinusitis	Altered Intercellular Communication	According to CT scans, about 40% of the patients had pansinusitis, and about 30% of the patients had anterior and posterior ethmoiditis combined with inflammation of other sinuses.	7782970
Gingivitis, Dental caries	Altered Intercellular Communication	Also there was an association between presence of defective restorations and manifest caries and the incidence of gingival inflammation.	7782977
Arthritis	Altered Intercellular Communication	Our data suggest that the presence of gelatinase-B is a reflection of the inflammatory condition of the joints of patients with arthritis, and that the activation of gelatinase-B in the joints, which may occur in a u-PA/plasmin dependent and/or a stromelysin dependent way, contributes to the progression of arthritis.	7783051
Inflammation, Pain Distress Question	Altered Intercellular Communication	Furthermore, the results indicate that the effect of inflammation on mental distress is mediated by pain.	7783072
Inflammation, Mucoid degeneration	Altered Intercellular Communication	Histopathologic examination demonstrated neovascularization, disruption of collagen, and mucoid degeneration without inflammation.	7784585
Airway structure, Asthma	Altered Intercellular Communication	The level of bronchial responsiveness in those with definite asthma correlates with disease severity and markers of airway inflammation.	7785004
Airway structure, Wheezing	Altered Intercellular Communication	Since the outcome of wheeze in early childhood is very variable, a marker of underlying airway inflammation would be of practical value.	7785004
Airway structure, Wheezing	Altered Intercellular Communication	Either wheezy children of this age do not have airway inflammation or bronchial responsiveness is not a marker for it.	7785004
Bronchitis	Altered Intercellular Communication	Bronchial inflammation in chronic bronchitis assessed by measurement of cell products in bronchial lavage fluid.	7785007
Asthma, Bronchitis	Altered Intercellular Communication	Bronchial inflammation in chronic bronchitis has not been characterised as well as in asthma.	7785007
Inflammation, Injury of cornea	Altered Intercellular Communication	If rubeosis iridis or severe aqueous flare is present, preoperative treatment with intense topical and possibly periocular steroids might reduce inflammation, which might mediate corneal damage.	7786219
Inflammation, Neoplasms, Hyperemia	Altered Intercellular Communication	A clinical examination revealed a solid-appearing white tumor within the midiris stroma, accompanied by limbal-conjunctival hyperemia and anterior chamber inflammation.	7786221
Cushing Syndrome	Altered Intercellular Communication	Adrenocorticotropic hormone-independent bilateral macronodular adrenocortical hyperplasia associated with Cushing's syndrome.	7787995
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	When studied by fine-needle aspiration (FNA), such masses may yield necrosis, granulomatous inflammation, reactive histiocytes, and atypical epithelial cells.	7789247
PROS1 gene, Inflammation	Altered Intercellular Communication	Evidence of significant inflammation at first visit predicts progression of damage in the future, suggesting that patients with PsA should be offered more aggressive treatment early in the course of their disease.	7791162
Inflammation, Arthritis, Psoriatic	Altered Intercellular Communication	Gut inflammation in psoriatic arthritis: a prospective ileocolonoscopic study.	7791163
PROS1 gene, Inflammation, Arthritis, Psoriatic, Spondylarthropathies	Altered Intercellular Communication	Some forms of psoriatic arthritis (PsA) are classified as spondylarthropathy, and subclinical gut inflammation is found in spondylarthropathies.	7791163
Inflammation, Spondylarthropathies	Altered Intercellular Communication	Gut inflammation is only present in PsA subgroups that belong to the spondylarthropathy concept.	7791163
Inflammation	Altered Intercellular Communication	This suggests that the gut plays a role in the pathogenesis of locomotor inflammation in these subgroups.	7791163
Inflammation, Spondylarthropathies	Altered Intercellular Communication	The prevalence of gut inflammation in psoriatic spondylarthropathy is significantly lower than in nonpsoriatic spondylarthropathies.	7791163
Tuberculosis, Spinal, Tuberculosis	Altered Intercellular Communication	The author presents a case of tuberculosis inflammation of thoracic vertebra with cold abcess along the spinal column, Pott's disease, in a woman 42 years old, a worker, with subjective difficulties which had lasted over a year before the diagnosis was made.	7791686
Carcinoma of lung, Hypertrophic osteoarthropathy	Altered Intercellular Communication	Lung cancer containing growth hormone-releasing hormone associated with hypertrophic osteoarthropathy.	7792560
Inflammation	Altered Intercellular Communication	A reappraisal of the radiologic findings of acute inflammation of the epiglottis and supraglottic structures in adults.	7793372
Intraocular inflammation, Inflammation	Altered Intercellular Communication	Previous intraocular inflammation or surgery was the factor most strongly associated with marked inflammation on the first postoperative day (p < 0.01, compared to uncomplicated patients).	7795400
Microcytosis, Inflammation, Thalassemia, Chronic Kidney Diseases	Altered Intercellular Communication	Of these, 357 showed microcytosis, caused by iron deficiency (58%), thalassaemia minor (35%), inflammation (6%) or chronic renal failure (1%).	7796088
Inflammation, Primary malignant neoplasm, Leukocytosis, Communicable Diseases, Chronic leukemia (category), Hypoxia, Acute hemorrhage, Macrocytosis, Erythrocytosis, Anemia, Malignant Neoplasms, Chronic liver disease, Thrombocytosis, Liver Cirrhosis, Thrombocytopenia	Altered Intercellular Communication	The most common causes of normocytic anaemia (25 patients) were disseminated malignancy and acute blood loss; of macrocytosis (27 patients), chronic liver disease and cancer; of erythrocytosis (16 patients), chronic hypoxia; of thrombocytopaenia (48 patients), chronic liver disease and ITP; of thrombocytosis (47 patients), iron deficiency and inflammation; of leukopaenia or pancytopaenia (20 patients), cirrhosis and disseminated malignancy; and of leukocytosis (26 patients), chronic leukaemias in the elderly and infection in children.	7796088
Inflammation, Reflex Sympathetic Dystrophy, Fasciitis	Altered Intercellular Communication	These included incomplete release (2), post operative scarring around the median and ulnar nerves (2), laceration of the superficial palmar arterial arch (1), reflex sympathetic dystrophy (2), palmar fasciitis (1), and wound inflammation (3).	7797976
Refractory anemias	Altered Intercellular Communication	Sonography could reveal inflammatory conditions at early stages of RA when no radiographic changes were seen.	7799342
Hyperprolactinemia, Hypopituitarism	Altered Intercellular Communication	Magnetic resonance imaging revealed that the pituitary mass was the same as previously described, but hormonal investigation showed evidence of complete hypopituitarism and no hyperprolactinemia.	7800142
Inflammation	Altered Intercellular Communication	Pleural and pericardial biopsies showed fibrohyaline plaques and diffuse aspecific, chronic inflammation consistent with asbestos exposure.	7800198
Granulomatous inflammation, Vasculitis, CTCAE, Capillaritis	Altered Intercellular Communication	No evidence of granulomatous inflammation or vasculitis other than capillaritis was found in either lungs or kidneys.	7800964
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	Our data revealed that ICAM-1 was expressed not only in RA synovia but also in OA which is not ordinarily considered to be immunogenic inflammation, though the molecules were expressed on the flat endothelial cells and not HEV, without accumulation of lymphocytes.	7801197
Helicobacter pylori, Gastritis	Altered Intercellular Communication	We studied the prevalence of Helicobacter pylori in Sudanese subjects with gastroduodenal inflammation.	7801358
Inflammation	Altered Intercellular Communication	These findings suggest that thrombin may play a role in the recruitment of large granular lymphocytes in sites of inflammation.	7803285
Gingivitis, Dental Plaque	Altered Intercellular Communication	Urea cleaving activity of dental plaque may be a marker of gingival inflammation.	7803925
Intraocular inflammation, Traction detachment of retina, Coma, Post-Head Injury, Diabetic Retinopathy, Retinal Diseases	Altered Intercellular Communication	The causes of tractional detachment and shortening of the retina were: proliferative vitretinopathy complicating idiopathic rhegmatogenic detachment of the retina in 25 eyes, proliferative diabetic retinopathy in 12 eyes, post-traumatic proliferation in seven eyes, intraocular inflammation in four eyes and the cicatricial stage of retinopathy of the premature in two eyes.	7805114
Inflammation	Altered Intercellular Communication	Examination of a biopsy specimen failed to demonstrate the granulomatous inflammation one would expect according to the current dermatologic literature.	7805415
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Special stains showed numerous microsporidial spores within the regions of granulomatous inflammation and prominent necrosis.	7806048
Inflammation, Colitis	Altered Intercellular Communication	In 10 of the 12 colitis patients one or more of the histological features of the original disease (such as active inflammation, increased regeneration, atypia) were evident.	7807454
Inflammatory disease of mucous membrane	Altered Intercellular Communication	In 64% of pts histology showed signs of mucosal inflammation.	7808036
Bronchopneumonia, Pulmonary Embolism	Altered Intercellular Communication	The cause of acute pseudoabdomen was diaphragmatic pleural or basal pulmonary inflammation; 3) the eight patients with pulmonary embolism were all admitted in the Department of Pneumology with a wrong diagnosis of bronchopneumonia.	7808666
Inflammation, Centers for Disease Control and Prevention (U.S.)	Altered Intercellular Communication	Microscopic examination of the CDC and the abnormal "common channel" within the pancreas revealed identical fibrous thickening of the duct walls with focal chronic inflammation and loss of surface epithelium.	7809018
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	We investigated the possibility of measurably increased parameters of inflammation in the serum of cancer patients and examined the correlation of hemoglobin levels, serum iron, and markers of inflammatory response in 201 cancer patients.	7809592
Inflammation, Perforation (observation)	Altered Intercellular Communication	When the site of perforation is concealed by the peritoneal inflammation it should not be searched; when visible, it might be obliterated with the round ligament or an omental tissue strand, particularly if larger than 1 cm in diameter.	7809807
Allergic asthma, Hypersensitivity, Eosinophilic inflammation	Altered Intercellular Communication	Eosinophil inflammation is a common feature of allergic disorders and particularly in allergic asthma interest has been paid to related markers.	7813532
Inflammation	Altered Intercellular Communication	On physical examination there was evidence of local inflammation.	7813926
Alzheimers Disease", Neuronal loss in central nervous system	Altered Intercellular Communication	The aetiology and pathogenesis of Alzheimer's disease are currently poorly understood, but symptomatic disease is associated with amyloid plaques, neurofibrillary tangles, neuronal loss and numerous alterations of neurotransmitter systems in the CNS.	7816197
Inflammation, Psoriasis	Altered Intercellular Communication	These results do not support the hypothesis that extracellular PAF contributes significantly to the inflammation associated with psoriasis.	7818279
Tumor necrosis, Inflammation	Altered Intercellular Communication	Association with spontaneous tumor necrosis factor alpha production and markers of inflammation.	7818558
Myositis	Altered Intercellular Communication	Patients with amyopathic DM showed no muscle inflammation, and MRS data obtained during rest were normal.	7818575
Myopathic facies, No metabolic abnormalities, Inflammation	Altered Intercellular Communication	In contrast, muscles of patients with myopathic DM showed inflammation and metabolic abnormalities even during rest.	7818575
Inflammation, Demyelination, Multiple Sclerosis, MS gene	Altered Intercellular Communication	Patterns of inflammation, demyelination and oligodendrocyte pathology were studied in acute multiple sclerosis and during early and late exacerbations of chronic multiple sclerosis.	7820568
Tissue damage, Inflammation, MS gene	Altered Intercellular Communication	Our data indicate that the type and amount of inflammation, de- and remyelination, and of tissue damage vary between different forms of multiple sclerosis and between different stages of the disease, possibly reflecting different pathogenic mechanisms in a disease spectrum.	7820568
Inflammation, Skin Papilloma	Altered Intercellular Communication	Biopsy studies of the following pathologic entities were carried out: keratosis, chronic inflammation, and papilloma of the adult.	7822176
Inflammation, Fibrosis Assessment, Hepatic necrosis, Icterus, Chronic active hepatitis	Altered Intercellular Communication	The inflammation, hepatic cell necrosis and fibrosis were more marked in cases of chronic active hepatitis without past history of jaundice.	7822848
Intraocular inflammation	Altered Intercellular Communication	Persistent intraocular inflammation (Tyndall +) has been observed in all eyes postoperatively but it seems to disappear slowly.	7823519
Intraocular inflammation, Glaucoma, CTCAE, Traumatic aniridia	Altered Intercellular Communication	Rehabilitation of eyes with traumatic aniridia by implanting the new black diaphragm IOL still presents some unsolved problems, especially uncontrolled secondary glaucoma and prolonged intraocular inflammation.	7823519
Inflammation	Altered Intercellular Communication	C-reactive protein (CRP) is a well-known serum protein which increases during inflammation and deposits in damaged tissues.	7824175
HTLV-I Infections, Spastic Paraplegia, Myositis	Altered Intercellular Communication	The most common neurological picture associated with HTLV-1 infection is a slowly progressive spastic paraplegia often involving nerve and muscle inflammation.	7824454
Refractory anemias, Inflammation	Altered Intercellular Communication	Our data suggested that in RA the measurement of sIL-2R may certainly mirror the degree of chronic inflammation and the continuous activation of the immune cells in the joint, although the role of this molecule in the immune response is still unclear.	7824835
Inflammation, Hypersensitivity	Altered Intercellular Communication	At admission, more than half of the patients had displayed elevated levels of serum acid glycoprotein as evidence of an ongoing inflammation and subnormal recordings for serum albumin and delayed cutaneous hypersensitivity.	7825621
Virus-Associated Hemophagocytic Syndrome	Altered Intercellular Communication	Syndrome of inappropriate secretion of antidiuretic hormone in patients with lymphoma-associated hemophagocytic syndrome.	7827207
Lymphoma, Virus-Associated Hemophagocytic Syndrome	Altered Intercellular Communication	We report three lymphoma patients in whom the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) was observed during the course of lymphoma-associated hemophagocytic syndrome (LAHS).	7827207
Inflammation, Enthesopathy	Altered Intercellular Communication	Inflammation ('enthesopathy') at the pubic insertion of the inguinal ligament was the cause in 30 patients (32 groins).	7827891
Inflammation, Enthesopathy	Altered Intercellular Communication	Enthesopathy also occurred in five rectus and one adductor longus tendons (one patient had inflammation in both).	7827891
Fever, CTCAE	Altered Intercellular Communication	Inflammatory conditions of the aorta may present with non-specific clinical features, including unexplained fever.	7828392
Gastro-esophageal reflux disease with esophagitis, Esophageal	Altered Intercellular Communication	These results indicate that impaired motility in reflux oesophagitis is either an irreversible consequence of oesophageal inflammation, or a (pre-existent) factor in its pathogenesis.	7828965
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	These results suggest that inflammation of the gastric body mucosa caused by H pylori infection is associated with enlarged gastric body folds and inhibition of acid secretion in H pylori positive patients with enlarged gastric body folds.	7828975
Rectocolitis, Ulcerative	Altered Intercellular Communication	Thus calcipotriol can dampen the hyperproliferative state in ulcerative proctocolitis and could have a therapeutic role in the control of this inflammatory condition.	7829008
Inflammation	Altered Intercellular Communication	It is generally admitted, that after cholecystectomy, the cystic duct and the gallbladder remnant may cause symptoms, by being the site of inflammation.	7829468
Inflammation, Necrosis	Altered Intercellular Communication	Portal inflammation was present in all cases and lymphocytic piecemeal necrosis in eight cases, but intra-acinar inflammation associated with hepatocyte necrosis was observed in only five cases.	7829677
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	"Activated" perisinusoidal cells were present, especially in relation to areas of inflammation, necrosis, and fibrosis.	7829677
Lyme Disease, Retinitis, Inflammatory abnormality of the eye, Uveitis, Optic Neuritis	Altered Intercellular Communication	During a two-year period, 236 patients with prolonged external ocular inflammation, uveitis, retinitis, optic neuritis, or unexplained neuro-ophthalmic symptoms were examined for Lyme borreliosis.	7832219
Vasculitis, Leukocytoclastic, Cutaneous, Granulomatosis with polyangiitis, Necrotizing granulomatous inflammation	Altered Intercellular Communication	While no cutaneous lesion is specific for Wegener's granulomatosis (WG), several histopathologic entities, including leukocytoclastic vasculitis and necrotizing granulomatous inflammation, are characteristic.	7832276
Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Necrosis, Granulomatous inflammation, Granuloma Annulare, Vasculitis, CTCAE, Erythema Nodosum, Acute inflammation	Altered Intercellular Communication	Biopsies were subdivided into histologic groups that included leukocytoclastic vasculitis (31%), granulomatous inflammation (GI) (19%), nonspecific ulceration (4%), superficial dermal and epidermal necrosis without inflammation (2.7%), erythema nodosum (2.7%), granuloma annulare (1%), chronic inflammation (31%), and acute inflammatory lesions without vasculitis (9%).	7832276
Vasculitis, Leukocytoclastic, Cutaneous, Granulomatous inflammation	Altered Intercellular Communication	We found that the histopathologic subgroups of leukocytoclastic vasculitis and granulomatous inflammation correlated with different clinical courses.	7832276
Vasculitis, Leukocytoclastic, Cutaneous, Inflammation	Altered Intercellular Communication	Leukocytoclastic vasculitis developed shortly after onset of WG (median, 15 months vs. 35 months for patients with nonspecific chronic inflammation).	7832276
Granulomatous inflammation	Altered Intercellular Communication	Patients with granulomatous inflammation also developed WG at an early age (median age, 30 years) when compared with the control group.	7832276
Inflammation, Colitis	Altered Intercellular Communication	Colonoscopic biopsies revealed only minimal inflammation but numerous, prominent apoptotic lesions within crypt epithelium, suggestive of an autoimmune or graft-versus-host-like colitis.	7832281
Penile Erection, Erectile dysfunction	Altered Intercellular Communication	Our results suggest that adenosine seems to be an important neuromodulator for penile erection and can be an effective and alternative combination in the treatment of impotence.	7833226
Dislocations, Fracture, Neoplasms	Altered Intercellular Communication	Because higher levels of radiation are used, 3-D CT protocols are less indicated in patients with minor dislocation of fractures, tumors, and inflammations.	7833409
Inflammation	Altered Intercellular Communication	In vitro studies, as well as an animal model, have suggested that cholesterol crystals could have a role in inflammation of the joints.	7835026
Inflammation, destruction joint	Altered Intercellular Communication	The long-term presence of the cysts, without evidence of joint destruction, suggests that cholesterol crystal formation is probably a rare epiphenomenon, rather than a harbinger of inflammation.	7835026
Inflammation, Acantholysis	Altered Intercellular Communication	There was evidence of neither acantholysis nor inflammation.	7835059
Inflammatory Bowel Diseases	Altered Intercellular Communication	The results suggest that bone turnover in inflammatory bowel disease is characterized by low bone formation in the presence of normal levels of calcium-regulating hormones.	7835582
Inflammation, Biliary calculi	Altered Intercellular Communication	Gallbladder motor function in gallstone patients: sonographic and in vitro studies on the role of gallstones, smooth muscle function and gallbladder wall inflammation.	7836714
Cholecystitis, Biliary calculi	Altered Intercellular Communication	Although gallbladder wall inflammation was mild and comparable in specimens from both groups of patients, the thickness of the muscular layer was greater in hypocontractors than in contractors (1073 +/- 76 vs 745 +/- 75 microns, p < 0.01) and related inversely to postprandial ejected volume (r = -0.42; p < 0.03; n = 32) but positively to gallstone volume (r = 0.40; p < 0.03; n = 32).	7836714
Angioedema, Glomerulonephritis, Inflammatory abnormality of the eye, Lung Diseases, Obstructive	Altered Intercellular Communication	Eighteen patients with HUVS were identified, and high incidences of angioedema, ocular inflammation, glomerulonephritis, and obstructive pulmonary disease were found.	7837968
Angioedema, Inflammatory abnormality of the eye, Glomerulonephritis, Lung Diseases, Obstructive, Lung diseases	Altered Intercellular Communication	Angioedema, ocular inflammation, obstructive lung disease, and glomerulonephritis appear to be common in HUVS, and lung disease causes substantial morbidity and mortality.	7837968
Inflammation, Calcinosis, Necrosis	Altered Intercellular Communication	The specimens showed variable amounts of gliosis, tissue necrosis, calcification, inflammation, and vascular proliferation and hyalinization.	7838329
Inflammation	Altered Intercellular Communication	Relationship of alveolar permeability and lung inflammation in patients with active diffuse infiltrative lung disease detected by 99Tcm-DTPA radioaerosol inhalation lung scintigraphy and quantitative 67Ga lung scans.	7838450
Pneumonitis	Altered Intercellular Communication	Meanwhile, the quantitative Ga lung scan (GA) was performed as a Ga uptake index (GUI) to evaluate the severity of lung inflammation in active ILD.	7838450
Damage, Pneumonitis	Altered Intercellular Communication	The results show that no good correlation between the degree of AP damage and lung inflammation was found.	7838450
Damage, Pneumonitis	Altered Intercellular Communication	In conclusion, the relationship between the degree of AP damage and lung inflammation in active ILD is not significant.	7838450
Edema of eyelid, Cervical lymphadenopathy, Pharyngitis, Diarrhea, Irritable Mood, Anorexia	Altered Intercellular Communication	The course was accompanying with nonspecific signs and symptoms such as anorexia, irritability, mild diarrhea, palpebral edema, mild inflammation of pharynx, and mild occipital and cervical lymphadenopathy.	7838633
Inflammation	Altered Intercellular Communication	Severe inflammation (grades III-IV) was observed in 8 of 10 patients with SS (chi-square = 12.6; P < 0.0005).	7839102
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Early stroke lateralizes T-cell-mediated cutaneous inflammation.	7839398
Obesity, Gynecomastia	Altered Intercellular Communication	This observation leads to the assumption that obesity and/or an earlier maturation of the subjects with gynaecomastia may play a role in the development of breast tissue, although the possibility of an increased tissue sensitivity to hormonal action cannot be excluded.	7840497
Inflammation, Hemorrhage, Inflammatory Myofibroblastic Tumor, Subglottic stenosis, Tracheobronchitis, Stenosis of bronchus	Altered Intercellular Communication	Initial findings included subglottic stenosis in five (17%), ulcerating tracheobronchitis with or without inflammatory pseudotumors in 18 (60%), tracheal or bronchial stenosis without inflammation in four (13%), and hemorrhage without identifiable source in two (4%) patients.	7842215
Upper Respiratory Infections	Altered Intercellular Communication	Sixteen patients (8.6%) with recurrent respiratory tract inflammation (r-RTI) and 45 patients (24.2%) with sporadic RTI (s-RTI) were observed.	7842777
Goiter, Hypothyroidism	Altered Intercellular Communication	Genetic and hormonal factors may contribute to the low prevalence of both goiter and hypothyroidism in the adult males.	7843650
Portal inflammation, Necrosis	Altered Intercellular Communication	Phosphomonoester expressed as a fraction of total phosphorus (PME/P) showed a correlation with abnormal serum aspartate transaminase (AST), histological intralobular degeneration/focal necrosis, portal inflammation, and piecemeal necrosis.	7843719
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	In summary, 31P MR spectroscopy is a technique to detect intralobular degeneration, inflammation and necrosis and to a less extent fibrosis.	7843719
Inflammation, Necrotizing fasciitis, Cellulitis	Altered Intercellular Communication	Necrotizing fasciitis occurs when the inflammation (cellulitis) spreads beyond the umbilicus to include the subcutaneous tissue and underlying fascia.	7844710
Inflammation, Graft failure, Herpetic whitlow	Altered Intercellular Communication	Amongst the interesting recent findings of the analyses are that a past history of elevated intraocular pressure and early graft suture removal are associated with graft failure, as are the more well-established factors of inflammation, neovascularization, formation of synechiae and recurrence of herpetic eye disease.	7844940
Pleurisy, Pleural Effusion, Malignant	Altered Intercellular Communication	Determinations were made in pleural fluid from patients with malignant pleural effusion, before and during therapeutic quinacrine-induced pleural inflammation.	7846335
Pleurisy	Altered Intercellular Communication	The results suggest that TNF-alpha might contribute to pleural fluid exudation and that TNF-alpha and NO are of importance in induced pleural inflammation.	7846335
Inflammation, Diverticulum	Altered Intercellular Communication	Faecal stones were associated with diverticula in 11 cases and were cause of their development and inflammation.	7848110
Inflammation	Altered Intercellular Communication	We suggest that this phagocytosis of sickled red cells is the likely cause for the otherwise unexplained inflammation.	7848320
Inflammation, Squamous cell carcinoma	Altered Intercellular Communication	In a retrospective study of 60 patients with squamous cell carcinoma of the oral tongue, lymphocytic peritumoral inflammation was not found to be an objective prognostic marker.	7848649
Inflammation, Edema	Altered Intercellular Communication	Inflammation and edema are also common findings in nerve specimens.	7849376
Pseudomonas aeruginosa, Keratitis, Ulceration, CTCAE	Altered Intercellular Communication	Infection of the eye by Pseudomonas aeruginosa can result in corneal inflammation (keratitis) and ulceration, and permanent decrease in vision if not successfully treated.	7851113
allergic inflammation	Altered Intercellular Communication	Biochemical assessment of allergic inflammation activity demonstrated that ditek is most effective of the above three drugs both in relation to induction of clinical remission and to inhibition of allergic inflammation.	7853817
Inflammation	Altered Intercellular Communication	The course of the inflammation and the extent of the inflammatory process within the nail matrix produce two different patterns of nail plate surface abnormalities.	7857841
Inflammation, Fibrosis Assessment, Temporal Arteritis, Eosinophilic inflammation	Altered Intercellular Communication	We describe a 39-year-old patient with an unusual type of bilateral temporal arteritis characterized histologically by inflammation, diffuse eosinophilic infiltration, destruction of elastic tissue, and fibrosis.	7860056
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	There were signs of fibrosis with inflammation in her liver, kidneys and lungs.	7861643
Inflammation	Altered Intercellular Communication	MRI-determined synovial membrane volumes and early synovial enhancement may be objective quantitative markers of inflammation.	7863280
Inflammation	Altered Intercellular Communication	The implant was removed, and pathology demonstrated suppurative inflammation with limited vascular ingrowth.	7865449
Inflammation, Zoonoses	Altered Intercellular Communication	This zoonotic infection, spread by mosquito vectors from animal hosts to humans, is rarely encountered in the United States as a cause of periorbital inflammation.	7865454
Inflammation	Altered Intercellular Communication	A correlation between the hygiene status and chronic gingival inflammation in 14-year-old school children was found.	7867996
Granulomatous inflammation, Hemorrhage, Blood Vessel	Altered Intercellular Communication	All biopsies showed evidence of blood vessel damage with fibrinoid change or hemorrhage (or both) and granulomatous inflammation in and around vessel walls.	7868756
Smooth muscle (tissue)	Altered Intercellular Communication	Penile corporeal lacunar endothelium is active in the local neural control of corporeal smooth muscle relaxation by producing nitric oxide, a potent vasodilator neurotransmitter.	7869481
Inflammation, Burn of esophagus	Altered Intercellular Communication	The course of inflammation was followed up during combined treatment of 50 patients with pharyngeal and esophageal chemical burns.	7871661
Inflammation	Altered Intercellular Communication	The results of these three key laboratory tests may help to identify functional iron deficiency in the presence of chronic inflammation.	7872225
Cataract, Inflammation	Altered Intercellular Communication	Increased comfort and decreased inflammation of the eye by cooling after cataract surgery.	7872390
Inflammation, Arthropathy	Altered Intercellular Communication	Although it is widely accepted that CPPD crystal induces severe inflammation in arthropathy, little attention has been paid to the acute inflammation that may accompany the CPPD crystals in the ligamentum flavum.	7873850
Inflammation, Radiculopathy, Cervical	Altered Intercellular Communication	The local inflammation of the ligamentum flavum might have participated in the exacerbation of the cervical radiculopathy.	7873850
Inflammation, Ductal Carcinoma	Altered Intercellular Communication	Thus, we should pay careful attention to pseudocyst of the pancreas, especially when signs of diffuse chronic inflammation cannot be found, to help identify duct cell carcinoma in the early stage.	7874278
Inflammation, Hematuria, CTCAE, cell wall thickening, Malignant Neoplasms, Bullous, Dysuria	Altered Intercellular Communication	Our experience indicates that in the child with hematuria, dysuria, and frequency plus cystographic or sonographic demonstration of a bladder with reduced capacity and circumferential wall thickening or sonographic findings of isoechoic bladder wall thickening (focal, multifocal or circumferential distribution), intact mucosa, and bullous lesions should strongly suggest inflammation and not malignancy.	7877202
Portal inflammation, Necrosis	Altered Intercellular Communication	In contrast, HIV-positive patients with CD4+ lymphocytes below 400 cells/mm3 showed a significantly lower grade of portal inflammation and piecemeal necrosis.	7877436
Ischemia, Fibrosis Assessment, Inflammation, Myocardial dysfunction	Altered Intercellular Communication	Factors including fibrosis, senescence, ischemia, inflammation, catabolism and hormonal response may contribute to myocardial dysfunction.	7878407
Ischemia, Fibrosis Assessment, Inflammation, Myocardial dysfunction	Altered Intercellular Communication	Factors including fibrosis, senescence, ischemia, inflammation, catabolism and hormonal response may contribute to myocardial dysfunction.	7878407
Bronchitis, Chronic, Inflammation	Altered Intercellular Communication	Airways inflammation in subjects with chronic bronchitis who have never smoked.	7878554
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To study the ability of technetium-99m hexamethyl propylene amineoxime (HMPAO) labelled lymphocyte scintigraphy to quantify synovial inflammation, and to analyse the kinetics of lymphocyte retention in the joints of patients with rheumatoid arthritis (RA).	7880120
Refractory anemias, Inflammation, Joints, Trauma, Nervous System	Altered Intercellular Communication	Our findings show that, in a study of a treatment of RA, it is quite possible for disease activity measures to appear controlled while inflammation continues in the small joints causing radiological damage.	7881839
Inflammation, Disease	Altered Intercellular Communication	We argue that small joint inflammation and damage should be recognized as one aspect of the RA disease process offering unique information and as such should be assessed independently.	7881839
Pain Distress Question, Inflammation, Arthropathy	Altered Intercellular Communication	The PTs were correlated to visual analogue scales (VAS) and values of articular disease activity, to define their relation with pain perception and joint inflammation.	7881842
Gastric metaplasia, Duodenal inflammation	Altered Intercellular Communication	A positive relation between extent of gastric metaplasia and duodenal inflammation score was present before treatment (r(s) = 0.74, p < 0.001) and was unchanged after treatment in the non-eradicator group (r(s) = 0.89, p < 0.001).	7883216
Inflammation, Gastric metaplasia	Altered Intercellular Communication	In the eradicator group, however, the inflammation score had significantly declined (p < 0.02) and the close relation with gastric metaplasia was no longer present.	7883216
Inflammation, Stomach Carcinoma, Gastritis, Infection caused by Helicobacter pylori, Peptic Ulcer	Altered Intercellular Communication	This study examines the relationship between Helicobacter pylori infection and peptic ulcer disease and gastric cancer--in particular, the presence or absence of bacteria, the grading of gastritis, and the degree of inflammation in the antral and oxyntic mucosae.	7883217
Thyroid Diseases, Vocal Cord Paralysis, Inflammation	Altered Intercellular Communication	Vocal cord paralysis can be the result of benign thyroid disease by such mechanisms as compression, stretching, or inflammation.	7883546
Inflammation, Hypocholesterolemia	Altered Intercellular Communication	Evidence for inflammation as a cause of hypocholesterolemia in older people.	7884115
Embolism, Hemorrhage, Inflammation, Heart failure	Altered Intercellular Communication	A 69-year-old man was transferred to our hospital because of severe progressive heart failure, eyeground hemorrhage due to embolism and uncontrollable inflammation.	7884266
Inflammation, Atelectasis	Altered Intercellular Communication	The lesion was located in the outer portion of S5 and was found to consist of 2 elastic hard nodule surrounded by a atelectasis with inflammation.	7884987
Granulomatous inflammation, Peritonitis	Altered Intercellular Communication	Tuberculous peritonitis was diagnosed after omental biopsy obtained at mini-laparotomy showed granulomatous inflammation and positive isolation of AFB.	7885604
Intraocular inflammation	Altered Intercellular Communication	Retinal and choroidal biopsy in intraocular inflammation: a clinicopathologi study.	7886876
Inflammation, Data types - Address	Altered Intercellular Communication	The results add further support to the widely growing concept that inflammation and similar immune mechanisms may contribute to AD pathogenesis.	7888106
Inflammation, Fever, CTCAE	Altered Intercellular Communication	All patients had general signs of inflammation, fever (> 37.5 degrees C), and leucocytosis (> 10,000/ml) with or without purulent drainage.	7888255
Prostate carcinoma	Altered Intercellular Communication	Inflammatory conditions of the prostate are often difficult to distinguish from early stages of prostate cancer with imaging techniques.	7888435
Vascular Diseases, Inflammation, Edema, Parkinsonian Disorders, "Sjogrens Syndrome	Altered Intercellular Communication	These findings suggest that parkinsonism associated with primary Sjogren's syndrome is at least in part attributable to small vessel vasculopathy such as focal inflammation or edema.	7889697
Inflammation, Hyperemia	Altered Intercellular Communication	The others exhibited signs of inflammation and hyperemia.	7890002
Bronchiectasis, Atelectasis, Pneumonia, Granulomatous inflammation, Follicular Bronchitis/Bronchiolitis	Altered Intercellular Communication	Pathological findings included bronchiectasis in 10 patients, chronic bronchitis/bronchiolitis with lymphoid hyperplasia in seven, patchy organizing pneumonia in six, atelectasis in five, granulomatous inflammation in five, and abscess formation in four.	7890282
Granulomatous inflammation, Mycobacterium Infections	Altered Intercellular Communication	Three patients with granulomatous inflammation had associated atypical mycobacterial infection.	7890282
Inflammation, Gingival Hemorrhage	Altered Intercellular Communication	Subjects brushed for one minute to stimulate gingival bleeding associated with inflammation.	7891250
Gingivitis, Hemorrhage	Altered Intercellular Communication	Following the screening test, a bleeding index (BOP) was determined and used as an indicator of gingival inflammation.	7891250
Trachoma , Inflammation	Altered Intercellular Communication	Active trachoma was present in 19% of all persons examined, and 50% of all those with trachoma were found to have moderate to severe inflammation.	7891988
Inflammation, PICALM wt Allele	Altered Intercellular Communication	The PLATs were devoid of inflammation and sharply demarcated from the surrounding CLT.	7892044
Sarcoma, Malignant Fibrous Histiocytoma, Pleurisy, Childhood Angiosarcoma	Altered Intercellular Communication	In our previous study, we suggested that long-standing pleural inflammation might be an etiological factor for development of pleural soft-tissue sarcomas, especially malignant fibrous histiocytoma and angiosarcoma (AS).	7892158
Neoplasms, Down Syndrome, Rheumatoid Arthritis, Traumatic injury, Spinal instability	Altered Intercellular Communication	Trauma, neoplasia, rheumatoid arthritis, Down's syndrome, and inflammatory conditions are well-known causes of spinal instability.	7892658
MS gene, Inflammation, Autonomic nervous system disorders	Altered Intercellular Communication	In multiple sclerosis (MS) up-regulation of beta-adrenoceptors on peripheral blood mononuclear cells (PBMCs) has been attributed to either autonomic dysfunction, inflammation or a combination of the two.	7892755
septic	Altered Intercellular Communication	Results of hormonal measurements were compared 1) among the 4 groups, 2) between male and female patients, 3) between septic and nonseptic patients.	7895322
Inflammatory Bowel Diseases, Inflammation, Malignant tumor of colon, Ulcerative Colitis	Altered Intercellular Communication	A link between inflammation of the colon in inflammatory bowel disease (IBD) and the increased risk of colon cancer in ulcerative colitis (UC) may be provided by growth factor receptor genes.	7895532
Bacterial Vaginosis, Inflammation, Chlamydia trachomatis, Trichomonas Infections	Altered Intercellular Communication	Papanicolaou smears with inflammation were associated with bacterial vaginosis (P < .0001), excess white blood cells (P < .0001), trichomoniasis (P < .0001), abnormal wet mounts in general (P < .0001), and positive cervical cultures for C trachomatis and/or N gonorrhoeae (P < .001).	7898823
Gingivitis, Larsen syndrome, Periodontitis	Altered Intercellular Communication	We report here advanced periodontitis with severe gingival inflammation in a 29-year-old Larsen's syndrome patient.	7899108
Retinal Detachment, Inflammation	Altered Intercellular Communication	The results indicate that in addition to the size of breaks, extent of detachment, and presence of preoperative inflammation or low-grade PVR, iatrogenic problems also are important factors in the pathogenesis of severe PVR after surgery for retinal detachment.	7899716
Inflammation, Choroiditis, Optic Atrophy, Nerve Fibers, Retinal phlebitis	Altered Intercellular Communication	Atrophy of the nerve fiber and ganglion cell layers was present in 73% of the cases with MS and correlated with optic nerve atrophy; choroiditis was present in 11.5%; bilateral cyclitis without other foci of inflammation was present in 1 case; and retinal phlebitis was present in 20% (most of which were only identified after trypsin digestion).	7899721
Neuromyelitis Optica, Optic Neuritis	Altered Intercellular Communication	Optic nerve inflammation was present in two of the patients with neuromyelitis optica.	7899721
Inflammation, Necrosis	Altered Intercellular Communication	There were signs of acute intramural inflammation, with many polymorphonuclear leukocytes present in microabscesses, and spots of necrosis in the elastic layer at the site of the recipient artery.	7899843
Inflammation, Dermatologic disorders	Altered Intercellular Communication	Current knowledge about hemopoiesis and pathogenesis of the above dermatoses allow the changes being detected in the haemogramme to be considered secondary to chronic unspecific inflammation developing in the skin, being characterized, from the immunological standpoint, in a general sense, by T-cellular (tissue) immunodeficiency.	7900358
Inflammation, Thrombosis, Hyperplasia	Altered Intercellular Communication	We investigated coronary thrombosis, neointimal hyperplasia, and inflammation.	7900659
Inflammation, Angina, Unstable, Blood Clot	Altered Intercellular Communication	Inflammation without thrombus or accelerated progression occurred in 20% of unstable angina and 6% of stable angina samples.	7900659
Inflammation, Angina, Unstable, Thrombosis, Hyperplasia	Altered Intercellular Communication	In 52% of unstable angina cases, inflammation coexisted with thrombosis and/or neointimal hyperplasia.	7900659
Pain Distress Question, Inflammation, Dermatologic disorders, Destruction of tissue	Altered Intercellular Communication	The patients showed an apparent indifference about their extensive disabling skin disease, and no obvious complaints of pain, contrary to what might be expected from the pronounced tissue destruction and inflammation at the injection sites.	7905216
Inflammation	Altered Intercellular Communication	Successful therapy was associated with down-regulation of the autoimmune process and regression of islet inflammation.	7907681
Inflammation, Congenital MeSH qualifier	Altered Intercellular Communication	Similar pulmonary angiographic findings 1 year later and no sign of inflammation in the following year suggest that this condition is congenital in origin.	7909286
Inflammation, Calcinosis, Thickened, Atherosclerosis	Altered Intercellular Communication	Four patterns of arterial pathology were identified: (1) subendothelial inflammation ('endothelialitis') with little intimal thickening; (2) 'Endothelialitis' with thickening; (3) Intimal thickening without 'endothelialitis'; and (4) Intimal thickening with calcification and cholesterol clefts ('natural atherosclerosis').	7909922
Inflammation	Altered Intercellular Communication	We suggest that the lesions of chronic vascular rejection evolve, at varying rates, from an early 'endothelialitis' to a later stage with pronounced intimal thickening but no subendothelial inflammation.	7909922
Autoimmune hypoparathyroidism, AVP gene, Hypopituitarism	Altered Intercellular Communication	Hormonal studies revealed hypopituitarism and central diabetes insipidus, with associated primary autoimmune hypothyroidism.	7910396
Alcoholics, Inflammation, Hepatobiliary Disorder	Altered Intercellular Communication	The immunostaining intensity in the alcoholic patients with liver disease was eightfold (p < 0.01) and that in nonalcoholic patients with liver disease was fourfold, greater (p < 0.02) than the weak staining in normal livers; it correlated with the degree of inflammation and serum AST or gamma-glutamyl transpeptidase activities.	7912686
Acute inflammation, Cryptorchidism	Altered Intercellular Communication	The presence of the cremasteric reflex may be clinically significant in boys with suspected cryptorchidism or acute scrotal inflammation.	7912745
Inflammation	Altered Intercellular Communication	Lastly, many pro-inflammatory cytokines produced by DLC could contribute to inflammation and IL-10 to immunosuppression.	7912755
Refractory anemias, Inflammation, No immunologic abnormalities	Altered Intercellular Communication	No signs of inflammation or immunologic abnormalities were seen in RA duodenal-jejunal mucosa.	7914408
Drug-induced, Actual blood loss, Gastrointestinal inflammation	Altered Intercellular Communication	Nonsteroidal antiinflammatory drug-induced small intestinal inflammation and blood loss.	7914409
Actual blood loss, Gastrointestinal inflammation	Altered Intercellular Communication	Intestinal inflammation, blood loss, and gastroduodenal damage, and the response to treatment with DMARDs, were assessed in 46 patients taking NSAIDs.	7914409
Actual blood loss, Gastrointestinal inflammation	Altered Intercellular Communication	Intestinal inflammation and blood loss correlated significantly with one another (r = 0.43, P < 0.003), but not with the macroscopic or microscopic appearance of the gastroduodenal mucosa.	7914409
Actual blood loss, Gastrointestinal inflammation	Altered Intercellular Communication	Sulfasalazine reduced both intestinal inflammation and blood loss, whereas the other DMARDs did not.	7914409
Granulomatous inflammation	Altered Intercellular Communication	Skin biopsy revealed granulomatous inflammation with fungal hyphae resembling mucor within the giant cells.	7915467
Inflammation, Xanthomatosis, Dermatologic disorders, Reticuloendothelial System	Altered Intercellular Communication	Generalized normolipemic plane xanthomatosis is a rare cutaneous disorder, frequently associated with reticuloendothelial diseases and some disorders with inflammation.	7915470
homoserine kinase activity, Inflammation	Altered Intercellular Communication	This study suggests that HLA-DR antigens may be selectively inhibited by cytokines released during inflammation in HSK.	7916449
Inflammation	Altered Intercellular Communication	These data, while describing prominent TCR V beta 3 and V beta 6 gene detection, do not suggest that a common antigen-driven T-cell response promotes chronic inflammation in muscle of IBM patients.	7916906
Airway structure, Asthma	Altered Intercellular Communication	This study provides an in vitro model of cellular interaction between mast cells and AM, which might be relevant in the airway inflammation in asthma.	7917313
Meningioma, Astrocytoma	Altered Intercellular Communication	There is evidence that in women the growth of meningiomas and astrocytomas depends on the hormonal status.	7917914
Graft-vs-Host Disease, Gastrointestinal inflammation	Altered Intercellular Communication	The 99mTc white cell scan showed extensive uptake in the small bowel and the urinary excretion of 51Cr-EDTA was increased, the results being consistent with intestinal inflammation and gut GVHD.	7920324
Mastitis, Inflammation	Altered Intercellular Communication	Inflammation and dilatation of the mammary ducts were compared in two groups of women with proven histologic diagnoses of periductal mastitis (PDM, n = 133) and intraductal papilloma (IDP, n = 98) over an eight year period.	7921391
Inflammation, Squamous metaplasia	Altered Intercellular Communication	Duct dilatation, periductal inflammation, and squamous metaplasia were assessed objectively by two pathologists without knowledge of the clinical parameters.	7921391
Inflammation, Squamous metaplasia	Altered Intercellular Communication	Women with PDM who were heavy smokers (more than ten cigarettes per day) had more periductal inflammation (p = 0.0006) and squamous metaplasia of the lactiferous ducts (p < 0.02) compared with light or nonsmokers.	7921391
Inflammation, physiopathological	Altered Intercellular Communication	The observation by MRI that the frequency of enhancement with gadolinium-DTPA, a marker for blood-brain barrier dysfunction, is significantly less in the primary progressive form, has led to the hypothesis that inflammation is less intense in this group.	7922463
Inflammation, MS gene	Altered Intercellular Communication	There was significantly more inflammation in secondary progressive multiple sclerosis (as judged by the frequency of perivascular cuffing and cellularity of the parenchyma) than in primary progressive disease.	7922463
Inflammation, Lymphocyte Activation	Altered Intercellular Communication	It is hypothesized that local events such as inflammation might be inductive of extramedullary blastic transformation.	7923067
Stenosis, Esophagitis	Altered Intercellular Communication	Endoscopy showed esophageal inflammation and a fixed stricture at the gastroesophageal junction.	7924728
Inflammation, Gastritis, Hypertrophic, Malignant Neoplasms	Altered Intercellular Communication	Large-forceps endoscopic biopsy performed immediately after ultrasonography in 86% (24/28) revealed acute or chronic inflammation in 67% (16/24), malignancy in 16% (4/24), and Menetrier's disease in 4% (1/24).	7926533
Pneumonitis	Altered Intercellular Communication	Acute lung inflammation: neutrophil elastase versus neutrophils in the bronchoalveolar lavage--neutrophil elastase reflects better inflammatory intensity.	7930030
Inflammation	Altered Intercellular Communication	Prospectively, morphologic findings of acute and chronic inflammation in the transbronchial lung biopsy specimens were compared with the numbers of neutrophils in the BALF and the concentration of PMN-Elastase in the same.	7930030
Inflammation	Altered Intercellular Communication	It may therefore be useful to the clinician in his attempt to detect acute inflammation in the lower respiratory tract.	7930030
Cerebral Angiitis, Dermatomyositis, Childhood Type, Myocarditis	Altered Intercellular Communication	Cerebral vasculitis and clinically important myocardial inflammation are rare in juvenile dermatomyositis.	7930410
Inflammation	Altered Intercellular Communication	Severe chronic inflammation of the mucous membranes in the eyes and upper respiratory tract due to work-related exposure to hexavalent chromium.	7930899
Inflammation	Altered Intercellular Communication	Chronic inflammation of the skin and mucous membranes following prolonged exposure to high doses of toxic hexavalent chromium is well known in the occupational medical literature.	7930899
Pain Distress Question, Inflammation, Fever, CTCAE, Dry cough, Hoarseness, polychondritis, Sighing respiration	Altered Intercellular Communication	In a 71-year-old woman suffering from recurrent fever, dry cough, pain during sighing, hoarseness and later severe inflammation of the cartilage of both auricles 'relapsing polychondritis' was diagnosed.	7935947
Inflammation, Arthropathy	Altered Intercellular Communication	Most frequent symptoms are inflammation of the auricles and nasal septum, joint disorders and inflammation of eye structures, larynx and trachea.	7935947
Inflammation	Altered Intercellular Communication	Chronic inflammation associated with the amyloid plaques may represent an acute phase response in the brain.	7936055
Granulomatous inflammation, Malignant Neoplasms	Altered Intercellular Communication	The clinical presentation and mammographic findings raised strong suspicions of malignancy, excluded by the histological examination, which made it possible also to rule out possible known causes of granulomatous inflammation of the breast.	7936770
Hypertension, CTCAE	Altered Intercellular Communication	Nine years after surgery, he is asymptomatic, without hypertension, and radiological and or hormonal evidence of recurrence.	7937454
Inflammation, Fasciitis, Neuroma, Myositis, CTCAE 5.0, Neurogenic atrophy	Altered Intercellular Communication	All eight who had a pectoralis major muscle biopsy had abnormal results: (neurogenic atrophy [six], fasciitis [three], myositis [one], chronic inflammation [one], free silicone [one], and neuroma [one]).	7939925
Inflammation, Cystic Fibrosis, Neutrophil Infiltration	Altered Intercellular Communication	Inflammation associated with neutrophil infiltration is a commonly observed feature of children with cystic fibrosis.	7940424
Kabuki make-up syndrome, Growth hormone neurosecretory dysfunction, Central Diabetes Insipidus	Altered Intercellular Communication	A case of Kabuki make-up syndrome with central diabetes insipidus and growth hormone neurosecretory dysfunction.	7942006
Granulomatous inflammation, Atrophic	Altered Intercellular Communication	The following histopathological changes were investigated as parameters: (1) cystic dilatation of the duct and/or the acini, (2) atrophy of the acini, and (3) granulomatous inflammation.	7942338
Inflammation, Cholestasis	Altered Intercellular Communication	Thus, in addition to inflammation, cholestasis and decline of functioning hepatic mass may influence cICAM-1 concentration.	7942624
Inflammation, Edema	Altered Intercellular Communication	We consider that the MRI abnormalities reflected focal inflammation and edema, and corresponded to the presumed ictal focus.	7943619
Inflammation, Arthritis, Reactive	Altered Intercellular Communication	To further evaluate the role of bacterial antigens in triggering inflammation in the joint in patients with reactive arthritis by studying local antibody synthesis in the joint.	7944640
airway disease, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	There was also a case where the entire bronchiolar tree was mildly but uniformly stenosed with mucous hypersecretion, chronic inflammation, and fibrosis, a pattern considered to correspond to small airways disease.	7944899
Choroidal Detachment, Endophthalmitis, CTCAE, Vitreous Detachment, Vitreous inflammatory cells	Altered Intercellular Communication	Advanced streptococcal endophthalmitis correlated with the most severe vitreous inflammation, vitreous membranes, and the most extensive posterior vitreous detachment, whereas gram-negative endophthalmitis correlated with choroidal detachment on initial echography.	7945035
Carcinoid Tumor	Altered Intercellular Communication	Hormonal factors may, therefore, be important in the aetiology of carcinoid tumours.	7947101
Inflammation, Phototoxicity	Altered Intercellular Communication	The reactivation was seen in an already receding phototoxicity test area but not in a less phototoxic, noninterval PUVA treated area, suggesting that the reactivation by methotrexate is related with the severity of light-induced skin inflammation.	7947193
Inflammation, Fever, CTCAE	Altered Intercellular Communication	During that time the signs of inflammation including fever such as an elevated white blood cell count and the presence of C-reactive protein (CRP) all improved while the blood cultures became negative.	7949778
Thyroid Crisis, Hyperparathyroidism, Primary, Hypercalcemia, CTCAE	Altered Intercellular Communication	Parathyroid crisis occurring in primary hyperparathyroidism is characterized by extremely high circulating levels of parathyroid hormone and acute onset of severe hypercalcemia.	7950156
Inflammation	Altered Intercellular Communication	Examination of the surgical specimen showed severe inflammation of the colon.	7951862
Airway structure, Bronchitis, Bronchitis, Chronic, Exacerbation	Altered Intercellular Communication	To examine the nature and the degree of airway inflammation in chronic bronchitis during exacerbations, bronchial biopsies and sputum were obtained in 11 subjects with chronic bronchitis examined during an exacerbation, and in 12 subjects with chronic bronchitis examined under baseline conditions.	7952628
Heart Diseases, Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Most cases are inactive and morbidity results from systemic arterial hypertension and heart disease; active cases have systemic complaints and laboratory abnormalities suggestive of ongoing inflammation.	7955601
Inflammation, Cyst, Swelling, Thrombophlebitis, Popliteal Cyst, Pain in calf	Altered Intercellular Communication	Pseudothrombophlebitis syndrome is the occurrence of calf pain and swelling caused by extrinsic compression of the popliteal vessels by an enlarging Baker's cyst or by calf inflammation that occurs as the result of a ruptured Baker's cyst.	7955690
Inflammation, Vulva, Neoplasms	Altered Intercellular Communication	Wide vulvar excision revealed chronic inflammation without residual tumor.	7957320
Inflammation, Gastritis	Altered Intercellular Communication	No histological counterpart was found for the macroscopic appearances of the gastric mucosa said to show inflammation proposed by the Sydney classification of gastritis.	7959220
Epiglottitis, Inflammation, Glossitis, Laryngeal Edema	Altered Intercellular Communication	The internal examination disclosed severe glossitis, epiglottitis and inflammation of the upper respiratory tract with prominent laryngeal edema.	7959476
Hormone abnormality, Weight decreased	Altered Intercellular Communication	As she was overweight (BMI; 33.6 kg/m2), weight loss was expected to improve her hormonal abnormalities.	7959530
Hormone abnormality, Weight decreased	Altered Intercellular Communication	The benefit of very low calorie diet was also noticed since it brought a rapid weight loss as well as rapid improvements of hormonal abnormalities.	7959530
Ileal ulcer, Fibrosis Assessment, Ductopenia, Acute and chronic inflammation	Altered Intercellular Communication	A biopsied liver specimen, taken at the second operation for the ileal ulcer, showed chronic portal inflammation associated with ductopenia and epithelial degeneration of the small interlobular bile ducts, but periductal concentric fibrosis was not found.	7959551
Lipogranuloma, Granulomatous inflammation	Altered Intercellular Communication	The biopsies were initially misinterpreted as xanthogranuloma or granulomatous inflammation.	7959645
Inflammation, Crohn Disease, Ulceration, CTCAE, Ischemia	Altered Intercellular Communication	Microscopically, all cases were characterized by distinctive areas of localized ulceration and active inflammation, the features of which were quite unlike those of Crohn's disease or ischaemia, separated by islands of normal mucosa.	7959646
Inflammation, Yersinia infections	Altered Intercellular Communication	The aim of the present study was to elucidate the connection between yersiniosis and chronic inflammation.	7960501
Inflammation, Periodontitis, Peri-Implantitis	Altered Intercellular Communication	These findings suggest that microbial pathogens associated with periodontitis occur more commonly around implants exhibiting gingival inflammation (GBI) and may contribute to peri-implantitis.	7965553
Upper Respiratory Infections	Altered Intercellular Communication	[Bacterial flora of recurrent acute inflammation of upper respiratory tract infections in children].	7967924
Upper Respiratory Infections	Altered Intercellular Communication	A group of children aged 3-13 years with recurrent inflammation of upper respiratory tract was investigated.	7967924
Inflammation, Alveolar Bone Loss	Altered Intercellular Communication	Alveolar bone loss was minimal during this period even in the presence of periodontal inflammation.	7968186
Inflammation, Hemorrhage, Meckel Diverticulum, Appendicitis, CTCAE, Obstruction, Peptic Ulcer	Altered Intercellular Communication	Usually Meckel's diverticulum is asymptomatic; when it's complicated by bleeding, obstruction and inflammation, occurs as a symptomatic lesion but it's difficult to diagnose, because its signs and symptoms are identical to such common as Crhon's disease, appendicitis, and peptic ulcer diseases.	7970056
Deficit, Asphyxia	Altered Intercellular Communication	Thus, this study provides evidence that perinatal asphyxia leads to chronic deficits in neurotransmission in the basal ganglia.	7970219
Deficit	Altered Intercellular Communication	Rats surviving asphyctic periods longer than 20 min at 37 degrees C showed chronic deficits in the release of neurotransmitters monitored with microdialysis in the basal ganglia.	7970219
Urethral Stenosis, Inflammation, Urethritis, Urethra	Altered Intercellular Communication	Although urethritis and urethral stricture may represent one end of the spectrum of repeated urethral trauma, minor degrees of inflammation need to be quantitatively determined while assessing two different catheters for intermittent catheterisation.	7970852
Urethritis	Altered Intercellular Communication	The degree of urethral inflammation in patients practising intermittent catheterisation was studied by urethral cytology and staining the smear by Papanicolaou's method.	7970852
Pituitary hormone deficiencies, Histiocytosis, Langerhans-Cell, AVP gene, Hypopituitarism	Altered Intercellular Communication	Evolving pituitary hormone deficiency is associated with pituitary vasculopathy: dynamic MR study in children with hypopituitarism, diabetes insipidus, and Langerhans cell histiocytosis.	7972767
Interstitial Cystitis, Cystitis	Altered Intercellular Communication	Relationships between bladder inflammation and other clinical features in interstitial cystitis.	7974939
Inflammation	Altered Intercellular Communication	The degree of mononuclear inflammation on bladder biopsy can be objectively quantified and might be a useful parameter for subgroup division.	7974939
Inflammation	Altered Intercellular Communication	The degree of mononuclear inflammation on bladder biopsy was classified as mild, with less than 100 mononuclear cells/high power field (HPF), or severe (100 or more mononuclear cells/HPF or lymphoid aggregates).	7974939
Inflammation	Altered Intercellular Communication	Associations were sought between degree of inflammation and other subjective and objective clinical features.	7974939
Inflammation	Altered Intercellular Communication	Five patients had severe inflammation and 11 had mild inflammation.	7974939
Inflammation, Bladder distention	Altered Intercellular Communication	The major finding was that the patients with severe inflammation experienced better symptom relief after cystoscopy with bladder distention under anesthesia.	7974939
Granulomatous prostatitis	Altered Intercellular Communication	Granulomatous prostatitis is an inflammatory condition of the prostate which presents rarely in the urological practice.	7976705
Inflammation	Altered Intercellular Communication	H. pylori-positive patients had a significantly greater association with features of severe active CAG (chronic inflammation and polymorph activity) than H. pylori-negative patients.	7976771
Inflammation, Lower respiratory tract infection	Altered Intercellular Communication	No changes occurred in the chest infection group for these markers of inflammation.	7976776
Inflammation, Pseudotumor	Altered Intercellular Communication	Six patients had symptoms and laboratory data suggesting active inflammation caused by the pseudotumor.	7976880
Excessive tearing, Inflammation	Altered Intercellular Communication	The most common initial signs and symptoms were epiphora, chronic inflammation, or lacrimal mass.	7977578
Inflammation, Granulomatous abscess, Hair follicle structure	Altered Intercellular Communication	In the third biopsy 5 weeks after a second praziquantel treatment, no eggs were found, but a partly granulomatous abscess forming inflammation affecting a hair follicle was still present.	7978075
Acute and chronic inflammation	Altered Intercellular Communication	Patients with H. pylori and/or moderate to severe chronic and acute inflammation and epithelial mucin depletion had lower alcohol dehydrogenase activity in the antrum, but not in the fundus.	7978087
Painful intercourse female, Inflammation, Traumatic injury	Altered Intercellular Communication	Half of the patients, however, had an obvious aetiology for dyspareunia (trauma or inflammation) not related to pSS.	7979594
Painful intercourse female, Inflammation	Altered Intercellular Communication	Dyspareunia is a frequent symptom in these patients and local perivascular in these patients and local perivascular inflammation may contribute to the expression of this manifestation.	7979594
Inflammation, Capillaritis, Intra-alveolar hemorrhage, Vasculitis, CTCAE	Altered Intercellular Communication	Major pathologic changes included intra-alveolar hemorrhage (four patients with P-ANCA+ patterns vs three patients with C-ANCA+ patterns), necrotizing capillaritis (four patients with P-ANCA+ patterns vs three patients with C-ANCA+ patterns), vasculitis (three patients with P-ANCA+ patterns vs two patients with C-ANCA+ patterns), and necrotizing granulomatous inflammation (two patients with P-ANCA+ patterns vs one patient with C-ANCA+ patterns).	7979916
Granulomatous inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Unusual pathologic findings included chronic interstitial fibrosis (two patients with P-ANCA+ patterns vs two patients with C-ANCA+ patterns), cavitary nodules with necrotic neutrophils and minimal granulomatous inflammation (one patient with P-ANCA+ patterns), and bronchiolocentric granulomatous inflammation (one patient with P-ANCA+ patterns vs one patient with C-ANCA+ patterns).	7979916
Conjunctivitis, Failure (biologic function)	Altered Intercellular Communication	Thus, preoperative subclinical conjunctival inflammation induced by previous topical medication was identified as a risk factor for failure of trabeculectomy.	7980134
Inflammation, Necrosis	Altered Intercellular Communication	A skin biopsy specimen demonstrated isolated neutrophilic inflammation and necrosis of the eccrine glands.	7980136
Chronic pyelonephritis, Nephritis	Altered Intercellular Communication	Long-term urethral catheterization increases risk of chronic pyelonephritis and renal inflammation.	7983294
Cessation of life, Pyelonephritis, Nephritis	Altered Intercellular Communication	To determine the prevalences of chronic pyelonephritis and chronic renal inflammation in elderly nursing home patients at the time of death and to assess correlation with urethral catheterization and other putative risk factors.	7983294
Chronic pyelonephritis, Nephritis	Altered Intercellular Communication	Prospective assessment of risk factors with the prevalences of chronic pyelonephritis and renal inflammation at autopsy.	7983294
Nephritis	Altered Intercellular Communication	Antemortem assessment of risk factors for renal inflammation, including a search for any urethral catheterization in the person's life.	7983294
Inflammation, Urinary Calculi	Altered Intercellular Communication	Urinary tract pathology was assessed for gross and microscopic evidence of inflammation and urinary tract stones.	7983294
Chronic pyelonephritis, Bacteriuria, Nephritis	Altered Intercellular Communication	The duration of catheterization was significantly associated with increasing prevalence of bacteriuria, polymicrobial bacteriuria, chronic pyelonephritis, and chronic renal inflammation.	7983294
Chronic pyelonephritis, Nephritis	Altered Intercellular Communication	The prevalence of chronic renal inflammation without chronic pyelonephritis was significantly greater than that of chronic pyelonephritis: the prevalence was 43 percent (20/47) when catheterized > 90 days and 18 percent (12/65) when < or = 90 days (P < 0.05).	7983294
Acute pyelonephritis, Nephritis, Diastolic hypertension, Hydronephrosis	Altered Intercellular Communication	Chronic renal inflammation was associated with hydronephrosis, ureteral dilatation, acute pyelonephritis and diastolic hypertension.	7983294
Chronic pyelonephritis, Nephritis	Altered Intercellular Communication	Chronic pyelonephritis and chronic renal inflammation are associated with long-term catheterization.	7983294
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	The mean histological scores for the necro-inflammatory parameters: portal inflammation, piecemeal necrosis, spotty necrosis and fibrosis improved, but the changes did not reach statistical significance.	7984968
Leydig cell hyperplasia, Primary seminoma, Neoplasm Metastasis	Altered Intercellular Communication	A solitary right iliac lymph node metastasis, but not the primary seminoma, contained human chorionic gonadotrophin- (HCG) producing syncytiotrophoblast, which was regarded as the hormonal stimulus for Leydig cell hyperplasia and elevated serum testosterone.	7985328
Refractory anemias, Inflammation	Altered Intercellular Communication	In RA patients, there was a positive correlation of GranB expression with serum levels of acute-phase reactants, but not with histologic scores for inflammation.	7986219
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	In the OA patients (n = 33), the serum levels of MMP-3, but not of MMP-1 or TIMP-1, were significantly elevated and correlated strongly with the articular index but poorly with objective and subjective functional capacity scores as well as with serum levels of antigenic KS and systemic parameters of inflammation.	7986224
Inflammation, Data types - Address	Altered Intercellular Communication	Systemic inflammation and oxidative stress are major factors stimulating hepatic CP synthesis, and it remains to be determined whether increased CP concentrations in AD CSF and brain follow from similar mechanisms.	7986488
Inflammation, Neoplasms	Altered Intercellular Communication	Tumor localization and inflammation were found to be contributing factors to the elevated REE.	7987838
Sepsis, Hematologic Neoplasms	Altered Intercellular Communication	Circulating interleukin-6 (IL-6) concentrations correlate with disease activity in severe inflammatory conditions, in sepsis and in some hematological malignancies.	7987859
Bronchial wall thickening, Inflammation	Altered Intercellular Communication	Asthma is characterized by bronchial wall thickening due to inflammation.	7991828
Communicable Diseases, Inflammation	Altered Intercellular Communication	We found no correlation between the pathologic findings of infection and inflammation and the sonographic appearance of TDCs.	7992750
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	The muscle biopsy demonstrates mononuclear cell inflammation and vacuolated muscle fibers containing paired helical filaments and 6 to 10-nm fibrils, both resembling those of Alzheimer brain, and Congo-red positivity.	7992832
Inflammation, Myopathy, Hereditary	Altered Intercellular Communication	Hereditary inclusion-body myopathy designates patients cytopathologically similar but without inflammation.	7992832
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Pathologic examination of the excised periportal lymph node revealed chronic granulomatous inflammation with central caseous necrosis.	7993596
Granulomatous inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	T cell-mediated immunity is hypothesized to play an important role in the pathogenesis of granulomatous inflammation and vasculitis as found in patients with WG.	7994909
Autoimmune Diseases, Inflammation, Disorder of eye	Altered Intercellular Communication	The results of this work suggest that in some patients inflammation of the eyelid muscles may be an isolated feature of ophthalmopathy and remains as the only sign of a "subclinical" eye disease in patients with thyroid autoimmunity.	7994926
Inflammation	Altered Intercellular Communication	Meanwhile, the protein and IgG levels and activated CD4-cells were increased in the cerebrospinal fluid, indicating the involvement of chronic inflammation in the iron deposits in this case.	7994996
Tietzes Syndrome", THANATOPHORIC DYSPLASIA, TYPE I (disorder)	Altered Intercellular Communication	Tietze's disease (TD) is a self-limited, non-specific, inflammatory condition of the upper costochondral junction (CCJ).	7995288
Inflammation, Pancreatitis	Altered Intercellular Communication	Groove pancreatitis is an inflammation of the head of the pancreas which fills the anatomic space between the head of the pancreas on 1 side and the second part of the duodenum on the other.	7995583
Communicable Diseases, Inflammation, Inflammatory disorder	Altered Intercellular Communication	Among the patients with "tentative initial diagnoses" of infectious or inflammation-related diseases (133 cases), the diagnoses were confirmed in 102 patients by positive inflammation marker(s), whereas additional 22 cases with the diagnoses other than inflammation-related diseases were found to be in the inflammatory status by these tests.	7996715
Communicable Diseases, Inflammation	Altered Intercellular Communication	These results indicate that (1) simultaneous measurements of CRP, leukocyte number and leukocyte differential fraction are useful for the confirmation of early stage of inflammation and evaluation of the nature of infectious diseases; (2) measurement of serum sialic acid levels is more desirable for the evaluation of inflammatory status than ESR; and (3) serum protein profile can be substituted by sialic acid for the evaluation of acute inflammatory status alone.	7996715
Airway structure	Altered Intercellular Communication	Exposure to a combination of sulphur dioxide and nitrogen dioxide in concentrations that could be encountered in heavy traffic enhances the airway response to inhaled allergen, possibly as a result of previous airway inflammation.	7996960
Inflammation	Altered Intercellular Communication	The most important complications were corneal pathology (2065/4104) and inflammation (1370/4104).	7997328
Inflammation, physiopathological	Altered Intercellular Communication	Indications of this chondro-perichondral graft have been widened to cases of unsuccessful first intention myringoplasty and to certain cases of progressive perforations occurring in a setting of inflammation or tubal dysfunction.	7998753
Pleurisy	Altered Intercellular Communication	Epstein-Barr virus-associated primary malignant lymphomas of the pleural cavity occurring in longstanding pleural chronic inflammation.	8001926
Inflammation, Pleural Lymphoma	Altered Intercellular Communication	This suggests a link between primary pleural lymphoma and the longstanding chronic inflammation, which could favor a clonal evolution of Epstein-Barr virus (EBV)-infected B cells through the production of growth factors or immunosuppressive cytokines produced by inflammatory cells.	8001926
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Scalp biopsy specimens from the frontal hair margin showed perifollicular fibrosis and lymphocytic inflammation concentrated around the isthmus and infundibular areas of the follicles.	8002649
Inflammation, Bronchiectasis, Atelectasis, Abnormally opaque structure (morphologic abnormality), Endobronchial Lesion, Decompression, external, Postobstructive pneumonia	Altered Intercellular Communication	Obstructive pneumonitis, the opacity that develops distal to an obstructing endobronchial lesion or external compression, is actually a combination of atelectasis, bronchiectasis with mucus plugging, and true parenchymal inflammation.	8004324
Honeycomb appearance	Altered Intercellular Communication	However, at autopsy in six patients, the predominant histologic pattern was that of alveolar septal inflammation and fibrotic honeycombing.	8004328
Bronchiolitis Obliterans Organizing Pneumonia, Fibrosis Assessment, Lung Injury, Honeycomb appearance	Altered Intercellular Communication	In addition, the histologic picture of BOOP may be a manifestation of early lung injury that can resolve or progress rapidly to alveolar septal inflammation, end-stage fibrosis, and honeycombing.	8004328
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Colonic IL-8 levels correlated significantly with the macroscopic grade of local inflammation, especially in patients with UC (P < 0.001).	8004812
Congestive heart failure	Altered Intercellular Communication	Static measurements of plasma neurohormones at rest may not be adequate to detect alterations in cardiovascular control mechanisms in congestive heart failure (CHF).	8005128
Inflammation, Intradermal Route of Drug Administration	Altered Intercellular Communication	We conclude that, in the studied population, unless inflammation is taken into consideration, serum ferritin has a limited value in the diagnosis of ID.	8007058
Keratopathy, Inflammation	Altered Intercellular Communication	Infectious crystalline keratopathy is a distinctive clinical entity characterized by bacterial replication within the corena without inflammation.	8008339
Inflammation, Blood Clot, Aneurysm, Vena cava structure, teratologic	Altered Intercellular Communication	The following variables which are useful for surgical planning were considered for each patient: aneurysm extent, characteristics of parietal thrombi, dissections, fixurations, inflammation signs, involvement of renal arteries, vena cava, ureters, duodenum, the presence of retroaortic renal vein or of other anomalies or associated conditions.	8008892
Inflammation, Aneurysm	Altered Intercellular Communication	Inflammation signs were overestimated (14/8) as well as adhesion between aneurysm and duodenum (17/13).	8008892
Inflammation, Carcinoma, Diverticulitis	Altered Intercellular Communication	Differentiating sigmoid diverticulitis from carcinoma on CT scans: mesenteric inflammation suggests diverticulitis.	8010253
Carcinoma, Diverticulitis of sigmoid colon	Altered Intercellular Communication	The purpose of this study was to analyze the usefulness of two specific CT signs of sigmoid mesenteric inflammation (fluid at the root of the mesentery and vascular engorgement) for identifying and differentiating sigmoid diverticulitis from carcinoma.	8010253
Inflammation	Altered Intercellular Communication	Two specific patterns of inflammation of the sigmoid mesentery were analyzed: fluid at the root of the sigmoid mesentery and engorgement of the sigmoid mesenteric vessels.	8010253
Inflammation, Anemia	Altered Intercellular Communication	They also characterize the anemia and determine its relationship to stage, inflammation, and mortality.	8010342
Chorioretinitis, Inflammation, Retinitis, Retinal Vasculitis, Iridocyclitis	Altered Intercellular Communication	In addition, flare values differed in the various inflammation groups, with human albumin concentration equivalents decreasing in the following order: acute iridocyclitis (n = 27, 10.81 +/- 21.12), chronic iridocyclitis (n = 19, 5.19 +/- 6.12), necrotizing retinitis (n = 6, 1.92 +/- 1.11), acute retinochoroiditis (n = 9, 1.46 +/- 2.35), retinal vasculitis (n = 24, 1.03 +/- 0.90), chorioretinitis (n = 5, 0.98 +/- 0.71), Fuchs' uveitis (n = 10, 0.52 +/- 0.25).	8012140
Intraocular inflammation	Altered Intercellular Communication	In this study we analysed changes in aqueous flare in eyes with various forms of intraocular inflammations.	8012140
Intraocular inflammation	Altered Intercellular Communication	We examined 100 eyes of 100 patients aged (mean +/- SD) 40.2 +/- 19.8 years with acute and chronic intraocular inflammations.	8012140
Intraocular inflammation, Exacerbation of cGVHD	Altered Intercellular Communication	Flare values (mean +/- SD) in the eyes with intraocular inflammations were 4.38 +/- 11.82 mg/ml human albumin equivalents and were significantly higher than in the group of normal eyes (0.11 +/- 0.06 mg/ml, P < 0.0001).	8012140
Perforation (observation)	Altered Intercellular Communication	Corneal ulceration and perforation may occur in the course of several systemic and ocular inflammatory conditions.	8013714
Communicable Diseases, Acute inflammation	Altered Intercellular Communication	There have been no cases of postoperative inflammation or infection.	8014046
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Age and functional correlations of markers of coagulation and inflammation in the elderly: functional implications of elevated crosslinked fibrin degradation products (D-dimers).	8014349
Inflammation	Altered Intercellular Communication	Both collapsed lung with and without superimposed inflammation also showed increased thallium activity.	8014669
Nerve palsy, Inflammation, Ischemia, Neoplasms, Unknown (origin) (qualifier value), Aneurysm, Congenital MeSH qualifier, Traumatic injury, Compression injury of nerve	Altered Intercellular Communication	The etiologies of the sixth nerve palsies were trauma (n = 7), tumor (n = 4), infection/inflammation (n = 3), nerve compression from aneurysm or increased intracranial pressure (n = 4), congenital (n = 1), ischemia (n = 2), and idiopathic (n = 1).	8014791
Diffuse panbronchiolitis, Respiratory Tract Infections, Bronchiolitis	Altered Intercellular Communication	Diffuse panbronchiolitis (DPB) is characterised clinically by chronic airflow limitation and respiratory tract infection, and pathologically by chronic bronchiolar inflammation.	8016789
ARCN1 gene, Diffuse panbronchiolitis, Bronchiolitis	Altered Intercellular Communication	The nature of bronchiolar inflammation in COPD and DPB is also different, possibly explaining the difference in bronchial responsiveness.	8016789
Inflammation, Villous atrophy	Altered Intercellular Communication	in two patients and two controls, mild villous atrophy was observed; there was also slight inflammation of the ileal and colonic mucosa occurring with the same frequency in both groups.	8017365
Inflammation, Stenosis, Cryptosporidium	Altered Intercellular Communication	Biopsy of the stricture revealed severe inflammation and marked cryptosporidial infestation.	8017371
Malignant neoplasm of urinary bladder	Altered Intercellular Communication	Our results suggest that the agents responsible for the high risk of bladder cancer in the black foot disease region may operate through an inflammation-based mechanism which increases the amount of DNA damage per mutagenic event.	8020137
Disability, Inflammation, Pain Distress Question	Altered Intercellular Communication	One of the most common causes of pain and disability in the upper limb is inflammation of the rotator cuff tendons.	8020201
Inflammation, Myopathy, myonecrosis	Altered Intercellular Communication	Muscle biopsies showed significant myopathic alterations, with foci of muscle necrosis in most patients and minimal lymphocytic inflammation in one patient.	8020274
Granulomatous inflammation, Lymphoma, Granuloma Annulare	Altered Intercellular Communication	Three patients displayed granulomatous inflammation in noncutaneous sites, either within the malignant lymphoma or in uninvolved tissues, and all three had atypical clinical presentations of granuloma annulare.	8021370
Intraocular inflammation, Macular Edema, Cystoid	Altered Intercellular Communication	IOL-related intraocular inflammations, cystoid macular edema or an elevated intraocular pressure did not occur in this group.	8022151
Arthritis, Gastrointestinal symptom, Inflammation	Altered Intercellular Communication	Finally, a 3-week course of treatment with metronidazole resulted in a complete remission of arthritis, gastrointestinal symptoms, and inflammation signs (ESR, CRP).	8023590
Inflammation, Neoplasms	Altered Intercellular Communication	A trend toward less inflammation within the tumor and toward more epithelioid cell type was noted in the Hispanic patients.	8023876
Inflammation	Altered Intercellular Communication	Muscle biopsy showed rimmed vacuoles and cytoplasmic inclusions together with lymphocytic inflammation.	8024828
Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	To characterize the evolution of inflammation in the adult respiratory distress syndrome (ARDS) and test the hypothesis that sustained alveolar inflammation is associated with a poor outcome in patients with ARDS, we performed fiberoptic bronchoscopy and bronchoalveolar lavage (BAL) in 125 patients and compared BAL cells and protein concentrations in survivors and nonsurvivors.	8025736
Respiratory Distress Syndrome, Adult, Inflammation, Sepsis	Altered Intercellular Communication	The cross-sectional data analysis suggests that sustained alveolar inflammation occurs frequently in patients with ARDS following sepsis and is associated with a high mortality.	8025736
Lupus Erythematosus, Discoid, Conjunctivitis	Altered Intercellular Communication	Immunoelectron microscopy identified sub-basal lamina deposits of immunoglobulin G. Discoid lupus erythematosus should be a suspected cause of chronic conjunctival inflammation; the diagnosis is substantiated by immunopathologic and ultrastructural studies.	8026068
Inflammation, S100A4 protein, human	Altered Intercellular Communication	Furthermore, the chronic inflammation preceding malignant transformation might enhance the probability of malignant transformation via chronic stimulation of the lymphoid tissue.	8027397
Inflammation, Chronic maxillary sinusitis	Altered Intercellular Communication	Assessment of inflammation in noninfectious chronic maxillary sinusitis.	8027503
Inflammation, Sinusitis, Chronic rhinitis, Chronic sinusitis, IL13 gene	Altered Intercellular Communication	Pathologic examination of the sinus mucosa and titration of inflammatory mediators in the sinus fluid were carried out to characterize inflammation in chronic sinusitis and determine whether patients with chronic allergic rhinitis (CAR) and sinusitis differ from patients with chronic nonallergic rhinitis (CNAR) and sinusitis.	8027503
Inflammation	Altered Intercellular Communication	In this state, the pathogen results in progressive, chronic inflammation intermediate between previously described saprophytic and invasive states.	8028079
Deglutition Disorders, Dysphonia, hyperfunction	Altered Intercellular Communication	Clinical manifestations are thyroid node without hormonal modifications or acute swelling of the gland with hormonal hyperfunction; other signs are dysphonia and/or dysphagia.	8028737
Fibrosis Assessment	Altered Intercellular Communication	[Extensive myocardial fibrosis in an 8-month old infant following an inflammatory condition of probable viral origin].	8030354
Inflammation, Prostatic pain, Chronic prostatitis	Altered Intercellular Communication	In a prospective study, TPS findings were analysed in 88 men with chronic prostatitis and 53 patients with prostatodynia, all of whom had undergone a standardized diagnostic procedure to detect inflammation.	8032834
Calcified (qualifier), Chronic inflammation	Altered Intercellular Communication	A statistically significant accumulation of prostatic calcifications and unilateral seminal gland alterations was demonstrated in patients with chronic inflammation.	8032834
Calcified (qualifier), Inflammation, Congenital Abnormality	Altered Intercellular Communication	Prostatic calcifications and seminal vesical abnormalities are regarded as typical signs of inflammation.	8032834
Gastric metaplasia	Altered Intercellular Communication	Gastric metaplasia in normal (inflammation-free) duodenal mucosa.	8034925
Vasculitis, vascular inflammations, Ischemia, Cerebrovascular accident	Altered Intercellular Communication	Isolated angiitis of the CNS is a disease of unknown etiology characterized by signs and symptoms of diffuse ischemia or recurrent strokes and histologic evidence of vascular inflammation.	8035919
Inflammation, Vasospasm	Altered Intercellular Communication	Correlation of clinical and angiographic features is consistent with the hypothesis that segmental narrowing initially results from reversible inflammation and vasospasm.	8035919
Retinal vasculopathy, Papilledema, Vitreous inflammatory cells	Altered Intercellular Communication	The inclusion criteria included individuals with a positive HLA-B27 who had at least one of the following findings: (1) severe vitreous inflammation; (2) papillitis; (3) retinal vasculopathy; or (4) pars plana exudates.	8035991
Inflammation, Sarcoidosis	Altered Intercellular Communication	This fact may relate to a spontaneous regression of inflammation in sarcoidosis, as a substantial number of cases in group B may in time regress spontaneously.	8036337
Tendinitis, Acute inflammation	Altered Intercellular Communication	The glycosaminoglycan composition of tendon specimens from patients with chronic tendinitis is consistent with acute inflammation and new matrix proteoglycan synthesis, even in relatively old tendon specimens and after at least one injection of corticosteroid.	8037495
Inflammation	Altered Intercellular Communication	X-ray as well as scintigrams revealed inflammation of the presacral soft parts involving the os sacrum and bone marrow.	8039453
Neurogenic Inflammation	Altered Intercellular Communication	Mast cell tryptase and chymase are potential regulators of neurogenic inflammation in psoriatic skin.	8039976
Tissue damage, Hepatitis	Altered Intercellular Communication	It was concluded that (1) Le(y) is an inflammation-associated but not a cancer-associated antigen; (2) the more the tissue damage advances, the more the antigen is expressed; and (3) hepatic and plasma Le(y) are, however, nonspecific markers of necroinflammatory liver diseases.	8042585
Gastrointestinal inflammation, Balantidiasis	Altered Intercellular Communication	Therefore, in a group of symptomatic patients with B. hominis infection, endoscopy typically did not show evidence of significant intestinal inflammation, and results of intestinal permeability testing with 51Cr-EDTA did not suggest impaired barrier function of the intestinal mucosa.	8042662
Inflammation, Fibrosis Assessment, Contracture	Altered Intercellular Communication	It rapidly progresses to joint contractures because of inflammation and fibrosis of the fascia.	8043253
Inflammation, Phlegmon, Appendicitis, CTCAE	Altered Intercellular Communication	Cecal leak or disruption after appendectomy for complicated appendicitis is a consequence of severity of disease and is related to residual abscess cavity, inflammation, phlegmon, and nonviable intestine.	8044380
Gingivitis, Alveolar Bone Loss, Dental caries	Altered Intercellular Communication	The significance of age, proximal caries, gingival inflammation, probing depths and the loss of lamina dura in the diagnosis of alveolar bone loss in the primary molars.	8046091
Inflammation	Altered Intercellular Communication	Although normal or pathological functions for APP are not well understood, several observations suggest that APP may play a role in cellular stress and inflammation at the endothelial cell/vascular barrier.	8046777
Inflammation	Altered Intercellular Communication	Changes in expression of APP during cellular stress or inflammation may contribute to pathological deposition of A beta.	8046777
Inflammation	Altered Intercellular Communication	In conclusion, GM-CSF-R could be detected in the synovial tissue where it can mediate the effects of this cytokine locally produced during RA inflammation.	8049356
Sleep Apnea, CTCAE, Acromegaly	Altered Intercellular Communication	We conclude that increased ventilatory responsiveness and elevated hormonal parameters of disease activity both contribute to the pathogenesis of central sleep apnea in acromegaly.	8049836
Tuberculosis, Pulmonary	Altered Intercellular Communication	A hormonal and radiological evaluation of adrenal gland in patients with acute or chronic pulmonary tuberculosis.	8050132
Pain Distress Question	Altered Intercellular Communication	This report suggests that picoTesla range MF may cause activation of neuronal transmission along partially demyelinated axons of pain conduction in the spinal cord.	8050852
Inflammation, Hypersensitivity, Eosinophilic inflammation	Altered Intercellular Communication	From these results, we conclude that erythromycin may suppress chronic inflammation except for an allergic reaction characterized by marked eosinophilic infiltration.	8051596
Idiopathic recurrent pericarditis, Myocarditis	Altered Intercellular Communication	We report a case of idiopathic pericarditis in a 71-year-old woman without a friction rub or electrocardiographic changes suggestive of pericardial inflammation.	8051789
Myocarditis	Altered Intercellular Communication	In this case, a gallium scan was very useful in assessing and monitoring the course of pericardial inflammation.	8051789
Granulomatous inflammation	Altered Intercellular Communication	After excision of the conjunctiva and the tarsus, enlarged by granulomatous inflammation, the free posterior border of the lower eyelid is nicely applied against the eyeball and the lower eyelid recovers its elasticity and practically normal tonus.	8051879
Inflammation, Injury of bile duct, Cholestasis, Ductopenia	Altered Intercellular Communication	One patient who received clindamycin had liver biopsy findings of marked cholestasis, portal inflammation, bile duct injury and bile duct paucity (ductopenia).	8053440
Inflammation, Carcinoma, Ascites, Necrosis, Small bowel obstruction, Intestinal Perforation	Altered Intercellular Communication	Narrow albumin gradient (exudative) ascites, usually due to peritoneal carcinoma or inflammation, has been noted in cases of necrotic or perforated bowel, but simple small bowel obstruction has not previously been appreciated as a possible cause for ascites.	8053442
Inflammation, Pouchitis, Ulcerative Colitis	Altered Intercellular Communication	Acute inflammation of the ileal reservoir (pouchitis) is the most frequent late complication and is characterized by endoscopic and histological changes of acute inflammation similar to ulcerative colitis with abdominal and sometimes systemic symptoms.	8054388
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Bacterial overgrowth is one of the most popular hypothesis, but the onset of the acute inflammation observed by us only in patients with previous ulcerative colitis and in some cases during the period of protective ileostomy suggests a multifactorial pathogenesis.	8054388
Inflammation, Pyometra, Occlusion of cervix, Malignant Neoplasms	Altered Intercellular Communication	Histological examination revealed a pyometra with inflammation and destruction of the endometrium and myometrium, and cervical occlusion with no evidence of malignancy.	8054795
Inflammation	Altered Intercellular Communication	Eventually, both main stem bronchi became stenotic secondary to inflammation, and the patient died 154 days following surgery.	8057026
Vasculitis, Disseminated Intravascular Coagulation	Altered Intercellular Communication	Hypothesis: disseminated intravascular inflammation as the inflammatory counterpart to disseminated intravascular coagulation.	8058778
Vasculitis	Altered Intercellular Communication	We hypothesize that this syndrome is part of a larger disease grouping: disseminated intravascular inflammation (DII).	8058778
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histology of the liver disclosed numerous giant cell hepatocyte transformations with the lobular architecture being slightly distorted by portal inflammation and fibrosis.	8061807
Inflammation	Altered Intercellular Communication	In the vicinity of GV the gastric mucosa shows inflammation signs but less severe.	8062065
Esophageal Varices, Inflammation	Altered Intercellular Communication	17 (17.5%) patients had multiple lesions with superficial inflammation and oesophageal varices as the commonest combination.	8062771
Inflammation, Carcinoma, Colorectal Carcinoma, Ulcerative Colitis	Altered Intercellular Communication	These findings show that carcinomas complicating CD and UC have strikingly similar clinicopathological features and suggest that a common underlying process, such as chronic inflammation, maybe important in the pathogenesis of colorectal carcinoma.	8063223
Communicable Diseases, Inflammation, Neoplasms	Altered Intercellular Communication	The head and neck region is exposed to bacteria and viruses, so it is possible that the tumor site can become infected and accumulate T cells involved in infection and inflammation.	8063616
Communicable Diseases, Inflammation, Inflammatory disorder	Altered Intercellular Communication	These results indicate that the V alpha 10 subfamily, the preferred T cell population in both TIL and T cells in inflammatory disease, might be involved mainly in inflammation or infection.	8063616
Alzheimers Disease	Altered Intercellular Communication	Physostigmine was administered to 6 Alzheimer patients to increase brain cholinergic neurotransmission.	8064320
Inflammation	Altered Intercellular Communication	Microscopic examination of the reference material showed inflammation in three specimens (18%), whereas it showed inflammation in 22 patient specimens (71%).	8064453
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Serum ferritin concentration in rheumatoid arthritis together with some plasma glycoproteins such as alpha 2-glycoprotein and C-reactive protein are part of the response to inflammation.	8064731
Nasal inflammation	Altered Intercellular Communication	Twelve patients had chest roentgenographic abnormalities, including a diffuse alveolar filling pattern (N = 8), a diffuse interstitial pattern (N = 2), and a combined interstitial and alveolar pattern (N = 2); three others had nasal inflammation.	8065182
physiopathological, Gout	Altered Intercellular Communication	The authors consider correction of hormonal dysfunction in gout to be advisable.	8067020
Retinal Detachment	Altered Intercellular Communication	Inflammation of the anterior chamber in rhegmatogenous retinal detachment was studied in 338 eyes with a laser flare cell meter.	8067298
Intraocular inflammation, Traumatic injury	Altered Intercellular Communication	It is a rare occurrence and most of the reported cases have been associated with histories of exposure to excessive heat, ocular trauma, or intraocular inflammation.	8067300
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In contrast to mucinous carcinoma, these benign mucous extravasation nodules were closely associated with the heterotopic pancreas, and showed significant inflammation and fibrosis but no overt epithelial anaplasia.	8067516
Mesothelial cell, Myocarditis	Altered Intercellular Communication	Compared with samples obtained at the time of pericardiotomy, those taken at 75 and 135 minutes demonstrated a significant progression in the mesothelial cell damage (p < 0.01), together with increasing evidence of pericardial inflammation (p < 0.01).	8067846
Cartilage destruction, Structure of bronchial cartilage, Congenital emphysema	Altered Intercellular Communication	The case is unusual because a congenital lobar emphysema associated with an aplasia of bronchial cartilage has to be considered as well as secondary cartilage destruction due to chronic relapsing inflammations.	8067871
Gingivitis, Dental caries	Altered Intercellular Communication	Our definition of root caries included primary decay on root surfaces, and a subject's periodontal state was described according to the presence or absence of gingival inflammation or periodontal pockets and subgingival calculus and/or overhangings.	8069889
Gingivitis, Periodontal Ligament, Dental caries	Altered Intercellular Communication	Subjects with a healthy periodontium seldom (4%) had any caries on root surfaces, whereas 15% had caries in conjunction with gingival inflammation, and 17% in conjunction with deepened pockets.	8069889
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	In 15 patients, there was histological evidence of chronic or acute nonspecific inflammation; no associations with the severity or the etiology of the cirrhosis were found.	8071520
Degenerative polyarthritis, Inflammation, KANTR gene, Collagen Diseases	Altered Intercellular Communication	Excluding soft-tissue inflammation and spasm, osteoarthritis is the most common rheumatic disease of the cervical spine.	8072500
Cessation of life, Inflammation, Specimen Type - Fistula	Altered Intercellular Communication	In a third patient with virally-induced ERF, treatment was associated with improvement of the inflammation of the fistula before the patient's death from pulmonary aspiration after 40 days of treatment.	8074130
Inflammatory Bowel Diseases, Ulcerative Colitis, Gastrointestinal inflammation, Symptoms, Crohn Disease	Altered Intercellular Communication	Findings were compared to levels of carotene in serum samples obtained from similarly aged females with either chronic inflammatory bowel disease (22 Crohn disease, 11 ulcerative colitis) or acute medical symptoms not associated with undernutrition or intestinal inflammation (N = 26), and 21 children of either sex with dyspeptic symptoms.	8075090
Inflammation, Hernia	Altered Intercellular Communication	There was no histological evidence of acute inflammatory reaction, but only of chronic inflammation which was probably caused by the hernia itself.	8075197
Inflammation	Altered Intercellular Communication	Histological features of ASLC are normal crypt architecture and acute lamina propria inflammation, but mixed acute and chronic inflammation can be found.	8076762
Inflammatory Bowel Diseases, Inflammation, Lymphoid hyperplasia, Epithelial hyperplasia, Granuloma, Lymphoid, Plasmacytosis, Goblet Cells	Altered Intercellular Communication	Histological features of IBD are diffusely abnormal crypt architecture, crypt atrophy, mixed lamina propria inflammation, basal plasmacytosis, basal lymphoid aggregates, basal lymphoid hyperplasia, isolated giant cells, epithelioid granulomas, goblet cell mucus depletion, and reactive epithelial hyperplasia.	8076762
Myositis	Altered Intercellular Communication	The data demonstrate a close interaction between cortical plate disruption and muscle inflammation.	8078653
Osteomyelitis, Inflammation	Altered Intercellular Communication	The extent of inflammation including soft tissue involvement was better appreciated with computed tomography in osteomyelitis, especially in mixed pattern cases.	8078653
Communicable Diseases, Inflammation	Altered Intercellular Communication	A clinical trial was made of a new gel ligenten intended for local urethral anesthesia and treatment of infection and inflammation in the lower urinary tracts.	8079402
Urethral Infection, Inflammation	Altered Intercellular Communication	Ligenten was given to 52 patients to manage bladder, prostate, urethral infection and inflammation, for local prophylaxis before cystoscopy, urethral bouginage and transurethral surgery.	8079402
Neoplasms	Altered Intercellular Communication	However, the association with hormonally active neoplasms suggested that the hormonal microenvironment may have played a role in the development of the myelolipomatous foci.	8080359
Inflammation	Altered Intercellular Communication	Both GLA and eicosapentaenoic acid which derives from ALA suppress inflammation and joint tissue injury in animal models.	8081671
Neoplasms, Intracranial, Inflammation, Oculomotor Nerve Paralysis, Aneurysm, Bone structure of cranium	Altered Intercellular Communication	Based on etiological analysis of 246 cases of oculomotor palsy, the causes of the disease were firstly aneurysm of the skull base and intracranial inflammation, followed by intracranial tumor and skull injury.	8082470
Chronic liver disease, Inflammation	Altered Intercellular Communication	These data indicate that IFN-alpha is expressed in the liver in HBV-related active liver diseases and that the reported suboptimal production of IFN-alpha by PBMC in HBV-related chronic active liver diseases may be due to a redistribution of the IFN-alpha-producing mononuclear cells into the liver, the site of inflammation.	8082512
Granulomatous inflammation	Altered Intercellular Communication	In vitro autoradiography of fresh tissue biopsies, using the SS analogue [125I-Tyr3]octreotide, showed binding at sites that were microscopically identified as granulomatous inflammation.	8082663
Airway structure, Asthma, Bronchial Hyperreactivity	Altered Intercellular Communication	Persistence of bronchial hyperreactivity despite intensive therapy with corticosteroids suggests that in at least some children with severe asthma, bronchial hyperreactivity may be especially long-lived, may be perpetuated by inhaled beta 2 agonists, or may exist independently of airway inflammation.	8083457
Epilepsy	Altered Intercellular Communication	It may be supposed that in patients long-term treated because of epilepsy the hormonal disturbances involve not only adrenal cortex but also higher parts of neuroendocrinological system.	8084362
Acromegaly, Pituitary Adenoma	Altered Intercellular Communication	Pituitary adenomas that cause hypersecretion of growth hormone lead to acromegaly in adults.	8085420
Inflammation, Asthma	Altered Intercellular Communication	Airway-like inflammation of minor salivary gland in bronchial asthma.	8087355
Inflammation	Altered Intercellular Communication	Detection of inflammation/infection with human polyclonal immunoglobulin G labelled with 99Tcm.	8087482
Neoplasms	Altered Intercellular Communication	99Tcm-IgG performs well in the identification of bone-joint lesions and rules out non-inflammatory conditions (with the important exception of tumours).	8087482
Inflammation, Hypertrophy	Altered Intercellular Communication	Hypertrophy and inflammation appeared to be the main pathological changes in 10 cases.	8088179
Wounds and Injuries, Neoplasms	Altered Intercellular Communication	The functionally dynamic bridging plate system has proved successful in cases of partial mandibular resections, after tumour resections or in cases of defects following traumas and inflammations.	8088657
Inflammation, Spondylarthropathies	Altered Intercellular Communication	Ileocolonoscopy and biopsies of patients with spondylarthropathy reveal gut inflammation in 62% of cases.	8088713
Inflammation	Altered Intercellular Communication	In order to better understand the pathogenetic mechanisms of spondylarthropathy-related gut inflammation, the follicle-associated epithelium was examined.	8088713
Inflammation	Altered Intercellular Communication	This study was designed to test the hypothesis that intensity of H pylori infection and the associated inflammation are similar in the cardia and the antrum and are greater in these locations than in the corpus.	8088767
Inflammation, Dental Plaque	Altered Intercellular Communication	Subgingival plaque was sampled in each subject from a single site exhibiting the greatest inflammation.	8089237
Granulomatosis with polyangiitis, Vasculitis, CTCAE	Altered Intercellular Communication	Wegener's granulomatosis (WG) is a systemic disease characterized by necrotizing granulomatous inflammation and vasculitis.	8089286
Anthrax disease, Arteritis	Altered Intercellular Communication	Temporal artery inflammation as a complication of anthrax.	8089518
Inflammation, Edema, Anthrax disease, Necrosis	Altered Intercellular Communication	After the oedema had resolved and the typical necrotic black eschar of anthrax had evolved, he developed acute inflammation of the right temporal artery.	8089518
Inflammation, Hemorrhage, Rupture of papillary muscle, myonecrosis, Infiltration	Altered Intercellular Communication	Histological examination of the ruptured papillary muscle revealed hemorrhage, muscle necrosis and small cell infiltration suggesting the presence of active inflammation with bacteria on it.	8089583
Intracranial Hemorrhage	Altered Intercellular Communication	We also supposed that the time of onset of intracranial hemorrhage might be related to the hemodynamic and hormonal changes occurring during pregnancy.	8090271
Inflammation	Altered Intercellular Communication	In the two latter groups serum HA levels may reflect the extent of synovial involvement and inflammation, rather than only unspecific information.	8091143
Pleural Effusion, CTCAE, Inflammation, Varicella Zoster Virus Infection, Cytomegalovirus	Altered Intercellular Communication	The case reported here suggests that the pleural effusion was caused by the infiltration of mononuclear cells to the pleura as a result of systemic inflammation, and the possible alternative of host immune response against CMV was related to recent Varicella zoster virus infection.	8091978
Disturbance, Inflammation	Altered Intercellular Communication	The first form is characterized by the disturbance of colon peristalsis, inflammation, segmentation of the colon wall and the presence of staged changes in the colon wall muscles.	8092937
Inflammation	Altered Intercellular Communication	However the recurrence of cellular inflammation was again observed in these regenerated tubuli.	8107305
Inflammation, Damage	Altered Intercellular Communication	The colorectal release of this substance from segments with active inflammation was greatly increased compared with that found in healthy controls and correlated to the mucosal damage defined by plasma protein leakage and endoscopic findings.	8112497
Granulomatous inflammation, Granulomatous Angiitis	Altered Intercellular Communication	Pathologic findings consisted mainly of granulomatous inflammation with lymphocytes, histiocytes, and multinucleated giant cells, and granulomatous vasculitis with micro-necrosis.	8114375
Inflammation, Specimen Type - Fistula	Altered Intercellular Communication	Bronchoscopically the fistula is 2 mm in diameter and reepithelization is started around the fistula at 14 POD and the fistula is completely closed and covered with reepithelized mucosa without inflammation at 100 POD.	8114400
Tuberculoma, Necrotizing granulomatous inflammation, Brain Neoplasms	Altered Intercellular Communication	However, based on pathological findings, the ring appearance and low intensity area medial to the ring in the outer part of the tuberculoma shown in MRI of our patient seemed to represent a chronic granulomatous inflammation and gave a clue to rule out the suspicion of metastatic brain tumors.	8115012
Systemic disease	Altered Intercellular Communication	Inflammation of the wall of the eyeball may extend to adjacent ocular tissues with blinding consequences and may be associated with potentially lethal systemic disorders.	8115160
Presenile dementia, palladium	Altered Intercellular Communication	Monoaminergic neurotransmitter systems are known to play an important role in neuropsychological functions and they are impaired in dementia of DAT and PD.	8115667
Inflammation, Fibrosis Assessment, Aneurysm	Altered Intercellular Communication	At operation, the patient was noted to have extensive peri-aneurysmal fibrosis and inflammation with a 1 cm thick aneurysm wall.	8120075
Granulomatous inflammation, Fibrosis Assessment, Pneumonia, Alveolitis	Altered Intercellular Communication	In 12 of these 14 patients the parenchymal opacification represented an active inflammatory process including alveolitis, pneumonia, and granulomatous inflammation, while in 2 patients it represented fibrosis.	8126273
Cataract, Inflammation	Altered Intercellular Communication	Posterior chamber lens implantation and cataract surgery in patients with sarcoidosis-associated uveitis can be well tolerated when absolute control of the inflammation is achieved.	8127567
Inflammation, Visual Acuity, Glaucoma, CTCAE	Altered Intercellular Communication	Pre-existing retinal pathology and glaucoma as a result of uncontrolled inflammation resulting in permanent ocular structural damage were found to be the most important factors for determining the postoperative final visual acuity.	8127567
Refractory anemias, Inflammation	Altered Intercellular Communication	Therefore penetration of unbound cM-T412 into the site of inflammation might determine the therapeutic effect in RA.	8128188
Communicable Diseases, Inflammation	Altered Intercellular Communication	To search for an association between gut infection, gut inflammation, and spondylarthropathies.	8129761
Inflammation, Crohn Disease, Chronic disease, Spondylarthropathies	Altered Intercellular Communication	Gut inflammation is frequent in patients with spondylarthropathy, and one-fourth of the patients who have chronic disease have early features of Crohn's disease.	8129761
Parkinson Disease, Inflammation, Inflammatory disorder	Altered Intercellular Communication	Whether the elevated gamma delta+ T cell population in Parkinson's disease reflects previously unrecognized inflammation or may occur also in non-inflammatory disorders remains to be elucidated.	8133310
Cataract, Inflammation	Altered Intercellular Communication	Dexamethasone versus diclofenac sodium eyedrops to treat inflammation after cataract surgery.	8133491
Inflammatory Bowel Diseases, Orbital Pseudotumor	Altered Intercellular Communication	These data suggest that ANCA of restricted specificities are not specific for inflammatory bowel disease (IBD), but are present in diverse conditions characterized by chronic idiopathic inflammation.	8137544
Respiratory Tract Diseases, Neutrophil migration, function, Pneumonitis	Altered Intercellular Communication	These results indicated that RXM acts by reducing pulmonary inflammation through reduction of neutrophil migration to inflammatory sites, and is effective on chronic lower respiratory tract disease.	8138676
Inflammation, Hemorrhage, Thrombosis, Ulceration, CTCAE, Calcinosis, Septicemia	Altered Intercellular Communication	Catheter-related septicemia determined by clinical and microbiological data as well as postmortem pathology; venous pathological changes such as mural hemorrhage, thrombosis, calcification, ulceration, and inflammation.	8139059
Autoimmune hemolytic anemia, Lymphoepithelioid lymphoma (clinical)	Altered Intercellular Communication	[Lennert's lymphoma associated with the syndrome of inappropriate secretion of antidiuretic hormone and autoimmune hemolytic anemia].	8139106
Refractory anemias, Inflammation	Altered Intercellular Communication	The clinical profiles and laboratory findings of 9 RA patients with positive ANCA revealed that they had suffered and treated for more than 10 years and had still active joint inflammation, like intractable RA.	8139127
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	The onset of the syndrome is acute, ranging from some days to a few weeks, characterized by inflammation but no rheumatoid factor.	8140403
Squamous Hyperplasia, Inflammation, Stasis	Altered Intercellular Communication	Other changes, probably resulting from chronic stasis of ingested materials in the lumen, included diffuse squamous hyperplasia (all cases), lymphocytic mucosal esophagitis (28 cases), lymphocytic inflammation of the lamina propria and submucosa with prominent germinal centers (all cases), and submucosal periductal or glandular inflammation with complete loss of submucosal glands in half of the cases.	8141427
Inflammation, Neurolysis	Altered Intercellular Communication	However, it cannot be determined whether this inflammation is a manifestation of ongoing nerve destruction or whether it is a secondary phenomenon.	8141427
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	The expression of receptors for somatostatin in veins of inflamed intestines suggests an active involvement of this peptide in the pathophysiology of inflammatory bowel disease and perhaps of inflammation in general.	8144000
Inflammation	Altered Intercellular Communication	It may be due to an alteration of bronchial epithelium secondary to lymphocytic inflammation and damage of bronchial glands.	8146721
Gastric Ulcer, CTCAE 5, Inflammation	Altered Intercellular Communication	Inflammation was found in 61.6% of the patients, in 15% gastric ulcer.	8147154
Fibrosis Assessment, Acute inflammation	Altered Intercellular Communication	We hypothesize that recurrent passage of biliary sludge may precipitate obstructive inflammation and fibrosis of the ampulla of Vater.	8147369
Airway structure, Attack behavior, Atopy	Altered Intercellular Communication	LTs would thus appear importantly involved in asthmatic attacks in atopic and non-atopic type patients, although other chemical mediators may give rise to airway inflammation.	8147706
Ulcerative Colitis	Altered Intercellular Communication	Values in ulcerative colitis showed greater variation and in those areas with acute inflammation mucosa was denuded of the mucus layer.	8150346
Inflammation, Superficial ulcer, Stenosis, Ulcer	Altered Intercellular Communication	The diseased ileum showed inflammation, erosions, ulcerations, and sometimes strictures.	8150350
Inflammation, Nasal Polyps, Asthma, Rhinitis	Altered Intercellular Communication	Nasal polyps are characterized by chronic eosinophilic inflammation and often coexist with rhinitis and asthma.	8151059
Cessation of life, Inflammatory disorder, Refractory anemias	Altered Intercellular Communication	The cause of death in RA is difficult to analyze accurately because RA itself is a chronic systemic inflammation disease.	8151583
Intraocular inflammation, Uveitis	Altered Intercellular Communication	Evaluation of laser flare-cell photometry in the appraisal and management of intraocular inflammation in uveitis.	8152769
Inflammation, Uveitis	Altered Intercellular Communication	The authors prospectively studied the amount, duration, and pattern of inflammation for well-defined uveitic conditions and evaluated the potential usefulness of laser flare-cell photometry in uveitis.	8152769
Inflammation, Uveitis	Altered Intercellular Communication	The authors' findings show that laser flare-cell photometry allows quantitative assessment of inflammation in uveitis and contributes to improved management of patients with uveitis.	8152769
Inflammatory Bowel Diseases, Stenosis, Colitis	Altered Intercellular Communication	Accumulating reports, however, show that nonsteroidal anti-inflammatory drugs (NSAIDs) may cause ileal and colonic inflammation and strictures that may mimic inflammatory bowel disease and other conditions.	8153791
Inflammation	Altered Intercellular Communication	Similar histologic findings were noted on these biopsies and included: mild chronic inflammation, lymphoid nodules, and crypt architectural changes.	8153859
Inflammation, Pain Distress Question	Altered Intercellular Communication	Only 9% of the untreated patients healed spontaneously after 50 d. Growth of the lesion, inflammation and pain were observed at the beginning of treatment.	8154018
Granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	Twenty-one fine needle aspiration biopsies were performed with a diagnosis of tuberculosis or granulomatous inflammation.	8155188
Tumor necrosis, Inflammation	Altered Intercellular Communication	Interleukin (IL)-1, tumour necrosis factor (TNF) and IL-6 are considered major mediators of local and systemic inflammation.	8155390
Inflammatory abnormality of the eye	Altered Intercellular Communication	The ocular inflammation was due to caterpillar's hair presence in the anterior chamber and also to the toxin freed.	8155621
Inflammation, Peritonitis	Altered Intercellular Communication	The Mannheim peritonitis index provides an easy and reliable means of risk evaluation and classification for patients with peritoneal inflammation.	8156338
Coughing, Intra-abdominal	Altered Intercellular Communication	'Cough sign': a reliable test in the diagnosis of intra-abdominal inflammation.	8156359
Inflammation, Necrosis	Altered Intercellular Communication	Seventeen biopsy specimens were reviewed, and all exhibited varied histologic evidence of inflammation, reactive glandular changes, and cell necrosis.	8156508
Inflammation	Altered Intercellular Communication	These data suggest that peripheral and systemic indexes of inflammation are present in the disease and might be associated with mental deterioration.	8157733
Inflammation, Urticaria, Dry skin, Alopecia, CTCAE, Pruritus	Altered Intercellular Communication	Skin inflammation, urticaria, pruritus, alopecia, and dry skin have been reported in 0.5-1.5% of patients.	8159596
Inflammation, Necrosis	Altered Intercellular Communication	The lymph nodes contained granulomatous inflammation and areas of necrosis, but no organisms were identified.	8160721
Inflammation, Calculi, Acute Cholecystitis	Altered Intercellular Communication	Acute acalculous cholecystitis, inflammation of the gall-bladder without evidence of calculi, accounts for 2 to 15% of all cases of acute cholecystitis.	8161083
Drug Eruptions, Inflammation	Altered Intercellular Communication	Because the pill was swallowed without water, a transient delay in its passage through the esophagus resulted in localized mucosal inflammation and a drug-induced stricture.	8161907
Glomerulonephritis, Laryngitis	Altered Intercellular Communication	Laryngeal inflammation and kidney biopsy proven focal crescentic glomerulonephritis were also present in this patient.	8162485
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	A direct comparison of the joint-imaging properties of inflammation-specific- and non-specific monoclonal antibodies (Mabs) was possible in a patient suffering from long-standing, severe rheumatoid arthritis (RA).	8162942
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation in asthma may alter connective tissue matrix elements within airway walls leading to this decreased elastance and excessive smooth muscle shortening.	8162988
Inflammation, Pain Distress Question	Altered Intercellular Communication	The active substance, felbinac, readily, penetrates into the tissue affected and accumulates locally, selectively inhibiting inflammation and alleviating pain.	8163257
Inflammation	Altered Intercellular Communication	We discuss the involvement of these mutations in the pathogenesis of xanthomatous and xanthogranulomatous inflammation.	8163275
Xanthogranulomatous inflammation, Hypoxia	Altered Intercellular Communication	Further investigations are required to test whether impairment of aerobic energy production independent from mitochondrial DNA mutations (eg, by hypoxia or microbial toxins) similarly can cause the accumulation of lipid-laden macrophages and explain the persistency of xanthogranulomatous inflammation.	8163275
Inflammation, Dental caries, Periodontal Diseases, Traumatic injury	Altered Intercellular Communication	The disease causes were dental caries or periodontal disease in 95 (45.5%), trauma in 58 (27.8%), and inflammation in 32 patients (15.3%).	8163882
Meningitis	Altered Intercellular Communication	Gadolinium-enhanced MRI was essential in identifying meningeal inflammation and locating suitable biopsy sites.	8164828
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Cytokine pathways are central to the perpetuation of synovial inflammation in rheumatoid arthritis (RA).	8165444
Inflammation	Altered Intercellular Communication	In 25.6% of the cases, the anterior ethmoid displayed patterns of a chronic inflammation.	8166383
Inflammation, Traumatic injury	Altered Intercellular Communication	In the early postoperative phase, they do not seem to be appreciably influenced by the neuroendocrine response to trauma, by mediators of inflammation, or by the postoperative catabolic state.	8167177
Ulceration, CTCAE, Acute inflammation, Perforation (observation)	Altered Intercellular Communication	Among the more common side effects is acute esophageal inflammation leading to ulceration and occasionally to perforation.	8168761
Juvenile Temporal Arteritis, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Histologic features of the nodule were diagnostic of juvenile temporal arteritis and characterized by non-giant cell granulomatous inflammation of the temporal artery, occlusive fibrous intimal proliferation, and microaneurysmal disruption of the media.	8170196
Bronchial Obstruction	Altered Intercellular Communication	Water from well 6 can be used in nonobstructive processes, whereas that from well 32 is effective in inflammation-induced bronchial obstructions and is fit to stimulate respiratory reserves.	8171840
Inflammation	Altered Intercellular Communication	The basal mean score for the signs and symptoms of inflammation, was significantly reduced (P < .001), with no significant difference between the two groups, at days 8 and 15.	8172273
allergic inflammation, eosinophil degranulation	Altered Intercellular Communication	We conclude that eosinophil degranulation is an important immunologic mechanism leading to allergic inflammation in cutaneously manifested CMA.	8173636
Pneumonitis, Neoplasms	Altered Intercellular Communication	Histology of the tumor revealed chronic inflammation of the lung tissue, that contained a spherule of a diameter of 20-60 microns and endospores of a length of 2-6 microns.	8176310
Proctitis, Inflammation	Altered Intercellular Communication	In patients with severe rectal inflammation, extrarectal dissection with stapled anastomosis may obviate the need for extended preoperative hyperalimentation or subtotal colectomy, but may carry a small increased risk of recurrent anorectal inflammation.	8176610
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation.	8178948
Inflammation, Cystitis, Necrosis, Squamous cell carcinoma, Exudate, Ulcer, Carcinoma, Transitional Cell, Nephrogenic metaplasia	Altered Intercellular Communication	Although diagnoses for the specimens with THP were variable (nine transitional cell carcinomas, one squamous cell carcinoma, two nephrogenic adenomas, and five cases of cystitis), the areas where THP was deposited in each of these cases invariably showed necrosis, inflammation, fibrinous exudate, ulcer, or crystalline material.	8179076
Inflammation, Necrosis	Altered Intercellular Communication	The mechanism for THP precipitation is not clear but is probably related to the mucosal changes, including inflammation and necrosis, which is always seen in areas of THP deposition.	8179076
Inflammation	Altered Intercellular Communication	The multiresponse star, which incorporates several biochemical parameters in one graphic illustration, may best characterize the complex nature of middle ear inflammation.	8179269
Pain Distress Question, Inflammation, Fever, CTCAE	Altered Intercellular Communication	[User knowledge and attitude in relation to drug use for pain, fever or inflammation].	8180301
Inflammation, Guillain-Barre Syndrome	Altered Intercellular Communication	Magnetic resonance imaging of nerve root inflammation in the Guillain-Barre syndrome.	8183455
Intraocular inflammation, Ischemia	Altered Intercellular Communication	Postoperatively, as the intraocular inflammation resolved, intraocular pressure (IOP) markedly decreased secondary, in our judgment, to ciliary body ischemia.	8183507
Inflammation	Altered Intercellular Communication	In some individuals, bioenergetic defects preceded other changes and persisted after resolution of inflammation.	8185702
Inflammation, Swelling	Altered Intercellular Communication	Stones of the salivary glands may cause recurrent swelling, ascending inflammation, and colic-like pain.	8186778
Airway structure, Asthma, Bronchoconstriction	Altered Intercellular Communication	Stimulation of exposed C-fibre afferent nerve endings by inflammatory mediators may contribute to airway inflammation and bronchoconstriction in asthma through the release of neuropeptides from collateral nerve endings.	8187029
Inflammation, Helicobacter Infections	Altered Intercellular Communication	We suggest the Helicobacter infection might have played a role in the pathogenesis of the inflammation and the peptic ulceration in this rare location.	8189008
Corticobasal degeneration, Inflammation, Leprosy	Altered Intercellular Communication	Further clarification of the mechanism of ganglion degeneration and the frequency of inflammation could come from immunohistology of tissues from African green monkeys with experimental polyneuritic leprosy.	8189085
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Several studies have suggested that TNF alpha is produced principally by mononuclear phagocytes and that it may play a role in inflammation, fibrosis and anti-tumor activity.	8189639
Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	Transbronchial lung biopsy revealed intraalveolar fibrosis as well as interstitial inflammation.	8189646
Inflammation, Peritonitis	Altered Intercellular Communication	Interleukin-8 during peritonitis in patients treated with CAPD; an in-vivo model of acute inflammation.	8190331
Inflammatory abnormality of the eye, Behcet Syndrome, Uveitis	Altered Intercellular Communication	The purpose of this study was to evaluate the role of quantitative 99Tcm-glucoheptonate (99Tcm-GH) scintigraphy in the assessment of patients with Behcet's disease who suffered from ocular inflammation (uveitis).	8190409
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	These preliminary findings suggest that, despite previously published reports in animals with experimentally induced uveitis, 99Tcm-GH scintigraphy may not be a very sensitive method for evaluating human ocular inflammations.	8190409
Inflammation, Vitreous inflammatory cells	Altered Intercellular Communication	Vitreous inflammation was controlled in 23 (88.5%) treated eyes, with fewer bouts of recurrent inflammation, and a corresponding improvement or stabilization of visual acuity in 20 (83.3%) eyes.	8190466
Sclerosis, Superficial ulcer, Inflammation	Altered Intercellular Communication	Erosions and sclerosis in vertebral end plates, changes of inflammation at scintigraphy or magnetic resonance (MR) imaging, and intact disks were hallmarks of the focal form.	8190957
Inflammation, Occluded, Fracture, Dislocations	Altered Intercellular Communication	Only 12 patients developed complications: porcelain fracture in 4, periodontal inflammations in 5, and a partial relapse of occlusion reduction and distal dislocation of the mandible in 3.	8191519
Granulomatous inflammation, Necrotizing, Vasculitis, CTCAE	Altered Intercellular Communication	The disease is characterized by necrotizing and granulomatous inflammation and vasculitis of the respiratory tract and kidney.	8191843
Inflammation, Atrophic, Abnormal degeneration	Altered Intercellular Communication	Pathology studies of the levator muscle and aponeurosis showed no evidence of inflammation, degeneration, or atrophy.	8193070
Airway structure	Altered Intercellular Communication	Biopsies were taken from healthy controls and from patients affected by upper airway inflammation of varying degree and duration.	8193664
Inflammation	Altered Intercellular Communication	Results suggest that viruses, bacteria, or both induce histamine production, which leads to increased inflammation in the middle ear.	8195602
Intraocular inflammation, Traumatic	Altered Intercellular Communication	However, slight persistent intraocular inflammation was observed in all of the eyes, more obviously in the traumatic cases.	8196924
Vascular Diseases, Inflammation, Retinal Detachment, Communicable Diseases, Corneal dystrophy, Diabetes Mellitus, Cataract, Traumatic injury, Malignant Neoplasms, Glaucoma, CTCAE	Altered Intercellular Communication	The most common underlying diseases included trauma (37.4%), malignant tumours (19.6%), systemic diseases (diabetes, vascular diseases) (17.1%), surgical diseases (retinal detachment, glaucoma, cataract, corneal dystrophy) (14.1%), infection and inflammation (7%).	8199109
Inflammation, Cholecystolithiasis, Traumatic injury, Neoplasms	Altered Intercellular Communication	In all three cases, the patients had had accompanying chronic or acute inflammation and two were accompanied by cholecystolithiasis, which made us aware of the importance of inflammation or trauma from stones in the pathogenesis of such neoplasms.	8199698
Inflammation, Tissue damage, Anemia, Hemolytic, Communicable Diseases, Kidney Diseases, Malignant Neoplasms, Thrombocytosis	Altered Intercellular Communication	The causes of thrombocytosis were infection (30.6%), hemolytic anemia (19.3%), tissue damage (15.2%), rebound thrombocytosis (14.8%), chronic inflammation (4.1%), renal disorders (4.1%), and malignancy (2%).	8200167
Inflammation, Infection, Kidney Diseases, Malignant Neoplasms, Thrombocytosis	Altered Intercellular Communication	Thrombocytosis secondary to infections was significantly more common in children under 5 years of age, whereas chronic inflammation, malignancy, and renal disorders were more common causes of thrombocytosis in children over 5 years of age.	8200167
Inflammation, Hypermetabolism	Altered Intercellular Communication	Rheumatoid cachexia: cytokine-driven hypermetabolism accompanying reduced body cell mass in chronic inflammation.	8200971
Inflammation, Hypermetabolism, Cachexia	Altered Intercellular Communication	The cytokines IL-1 beta and TNF-alpha cause cachexia and hypermetabolism in animal models, but their role in human inflammation remains controversial.	8200971
Inflammation	Altered Intercellular Communication	The histological examination of the resected anastomosis showed an unspecific inflammation of the mucosa.	8203179
Inflammation, Congestion, Edema, Ptosis	Altered Intercellular Communication	Inflammation, congestion, edema, and prolapse were more markedly improved in the D500 group than in the PL group.	8203789
Inflammation	Altered Intercellular Communication	Nonparticulate acidic liquid aspiration caused a significant increase (p < 0.05) in inflammation.	8204229
Inflammation, Edema	Altered Intercellular Communication	A nonsignificant trend was seen with simulated sucralfate aspiration for edema and inflammation.	8204229
Inflammatory disorder	Altered Intercellular Communication	It is unlikely that these hormonal influences are a common occurrence, but rather represent, in this case, a singular example of potential endocrine modulation of inflammatory disease.	8205410
Inflammation, Retinitis Pigmentosa, polychondritis	Altered Intercellular Communication	Relapsing polychondritis (RP) is a rare vasculitide characterized by recurrent inflammation of cartilagenous structures (auricular, nasal, laryngotracheal, articular) and specific sense organs (eyes and ear).	8206749
Inflammation, Myxoid degeneration	Altered Intercellular Communication	Microscopic examination of the valve aslo revealed myxomatous degeneration and no signs of the inflammation.	8207890
Malabsorption Syndrome, Gastrointestinal Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	The relation between faecal DL-lactate and intestinal inflammation or malabsorption was evaluated in 100 nonselected inpatients at a referral center for gastrointestinal disorders.	8209186
Inflammation, Hyaline body	Altered Intercellular Communication	Histologic examination of affected eyes disclosed cytoid bodies in the nerve fiber layer without inflammation.	8250076
Inflammation, Fever, CTCAE, Synovitis, Monoarticular, Polyarticular	Altered Intercellular Communication	Fever attributable to synovitis was present in 34% of the patients and was more prevalent in patients with polyarticular (50%) than monoarticular (20%) inflammation.	8257255
Communicable Diseases, Inflammation	Altered Intercellular Communication	The efficacy of indium-111-polyclonal IgG for the detection of infection and inflammation.	8271064
Communicable Diseases, Inflammation	Altered Intercellular Communication	The purpose of this study was to determine the efficacy of 111In-polyclonal immunoglobulin (IgG) for the diagnosis of infection or inflammation.	8271064
Communicable Diseases, Inflammation	Altered Intercellular Communication	The polyclonal IgG scan had a sensitivity of 97.9% and a specificity of 94% for infection or inflammation.	8271064
Communicable Diseases, Inflammation, bowel infarction	Altered Intercellular Communication	When only infection or severe inflammation such as bowel infarction was considered, the sensitivity remained the same but the specificity fell to 83%.	8271064
Communicable Diseases, Inflammation, Infection, Inflammatory disorder	Altered Intercellular Communication	Indium-111-polyclonal IgG is an effective imaging agent of infection and/or inflammation that is useful in a variety of infections and in severe inflammatory diseases.	8271064
Arthritis, Chronic arthritis	Altered Intercellular Communication	Of 10 patients with chronic arthritis (continuous joint inflammation for one year or more) despite multiple courses of antibiotics, 7 had consistently negative tests in samples obtained three months to two years after treatment.	8272083
Inflammation, Colitis, Ischemic	Altered Intercellular Communication	Colonoscopy revealed a sharply delineated segment with pronounced inflammation in the descending colon and the proximal sigmoid colon, suggestive for an ischemic colitis.	8272709
Inflammation, Neoplasms, melanoma	Altered Intercellular Communication	Intravenously administered R24, a murine IgG3 monoclonal antibody to GD3, induces inflammation and tumor regression at sites of metastatic malignant melanoma.	8281462
Intraocular inflammation, Endophthalmitis	Altered Intercellular Communication	Intraocular inflammation developed in the fellow eye and sympathetic ophthalmia was suspected.	8285899
Nephritis, Interstitial, Hypersensitivity, Nephritis	Altered Intercellular Communication	Acute interstitial nephritis is a disease characterized by renal inflammation and is thought to be secondary to a hypersensitivity reaction.	8285978
Inflammation, Papilloma, Necrosis	Altered Intercellular Communication	Two papillomas had marked nuclear atypia with background necrosis and inflammation.	8291351
Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	These cases, descriptively termed nonspecific interstitial pneumonia/fibrosis, were characterized by varying proportions of interstitial inflammation and fibrosis that appeared to be occurring over a single time span (i.e., the process was temporally uniform.)	8291652
Cessation of life, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	No deaths occurred in patients whose biopsies showed pure inflammation and no fibrosis.	8291652
Inflammation	Altered Intercellular Communication	Histological examination of bladder biopsies showed severe acute and chronic inflammation.	8295577
Granulomatous inflammation, Drug Allergy	Altered Intercellular Communication	Transbronchial lung biopsy showed granulomatous inflammation consistent with an allergic drug reaction.	8295578
Keratitis	Altered Intercellular Communication	The adhesion molecules ICAM-1, HLA-DR, PECAM-1, CD3, VCAM-1, LFA-1, and MAC-1 were selectively expressed in areas of corneal inflammation.	8302550
Keratitis	Altered Intercellular Communication	Adhesion molecules are detected readily at sites of corneal inflammation and may play a critical role in facilitating the recruitment of immune regulatory cells to these areas.	8302550
Granuloma, Papillary conjunctivitis, Structure of meibomian gland, Conjunctivitis	Altered Intercellular Communication	Light microscopy of the surgical specimens showed chronic conjunctival inflammation, papillary conjunctivitis, and meibomian gland abnormalities, including granuloma formation.	8302552
Osage language	Altered Intercellular Communication	We demonstrated that exacerbation of OSA by testosterone was associated with an increase in upper airway collapsibility during sleep, and that this improved after cessation of hormone administration.	8306057
Inflammation, Fibrosis Assessment, Aortic Aneurysm, Abdominal, Aneurysm	Altered Intercellular Communication	Inflammation and fibrosis do not only appear in an "inflammatory" aneurysm, but also in "ordinary" abdominal aortic aneurysms.	8307214
Inflammation, Aneurysm	Altered Intercellular Communication	According to histopathological criteria five different degrees of inflammation (Histological Inflammation Scale of Aneurysms) were found and patients were classified according to these criteria: grade A or mixed acute/chronic inflammation (4.5%); grade 0 or no inflammation (16.2%); grade 1 or mild chronic (57.7%); grade 2 or moderate chronic (16.2%); and grade 3 or severe chronic inflammation (5.4%) corresponding to an "inflammatory" aneurysm.	8307214
Aneurysm, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	No other differences could be demonstrated between sex, risk factors, cardiovascular diseases, previous abdominal operations, bacterial culture, aneurysm diameter, white blood count, cholesterol level in-hospital mortality when compared to the degree of inflammation.	8307214
Inflammation, Obstruction, Biliary calculi	Altered Intercellular Communication	The frequency of pneumobilia, biliary stone, history of cholecystectomy, biliary inflammation and obstruction were similar in the two groups.	8309091
Inflammation	Altered Intercellular Communication	Of 17 gastric biopsies with evidence of inflammation, H. pylori was found in 15 (88%).	8309388
Inflammation	Altered Intercellular Communication	The pathogenesis and, specifically, the significance of the periarterial inflammation, has been controversial.	8311666
Inflammation, Fibrosis Assessment, Cholangitis, Neoplasms	Altered Intercellular Communication	Bile ducts and peribiliary glands embedded within these tumors showed nonspecific fibrosis and inflammation, and inflammatory changes of the bile ducts were imperceptibly merged with those of the inflammatory tumor, raising the possibility that these tumors may have arisen in relation to cholangitis.	8314264
Thrombocytosis, Hematological Disease, Neoplasms, Traumatic injury	Altered Intercellular Communication	Reactive thrombocytosis (RT) has earlier been reported to occur as a response to various situations and conditions, such as post-splenectomy, hematopoietic disorders, major trauma and operations, neoplasms and inflammations.	8519519
Inflammation, Tissue Adhesions	Altered Intercellular Communication	Postoperative adhesions were suspected; laparoscopy surgery was made and uterine and anexial inflammation was observed.	8519944
Communicable Diseases, Inflammation	Altered Intercellular Communication	Each time when she has a feverish infection, a recurrence of inflammation can be seen within the hyperpigmented areas.	8520067
Inflammation, Sore to touch, Swelling, Erythema	Altered Intercellular Communication	Redness, swelling, and tenderness indicated presence of acute inflammation in the calf.	8521641
Communicable Diseases, Sarcoidosis, Granulomatous inflammation, Granulomatosis with polyangiitis, Oxalosis	Altered Intercellular Communication	Drug (aspirin, gentamycin, or combination of drugs), infection (Echerichia coli or various organisms), and sarcoidosis accounted for granulomatous inflammation in three patients each, Wegener's granulomatosis and oxalosis resulting from intestinal bypass in one patient each, and in one patient the possible cause could not be determined.	8522308
Communicable Diseases, Granulomatous inflammation	Altered Intercellular Communication	Except for biopsies of granulomatous inflammation resulting from infection, in which neutrophils predominated, in all other biopsies, T cells and macrophages made up most of the inflammatory cell infiltrate.	8522308
Inflammation, Hip joint pain, Bursitis	Altered Intercellular Communication	It is also recognized that soft tissue inflammation about the hip, such as trochanteric bursitis, can lead to hip pain after THA.	8523018
Presenile dementia, Inflammation, "Alzheimers Disease	Altered Intercellular Communication	The peripheral benzodiazepine binding sites associated with microgliosis and cellular inflammation in Alzheimer's disease at postmortem are undetectable by PET using [11C]PK 11195 in patients with mild-to-moderate dementia.	8523106
Refractory anemias, Inflammation	Altered Intercellular Communication	Combination therapy with multiple antirheumatic agents successfully controlled joint inflammation in 167 of 169 patients with seropositive RA; complete remission was achieved in 43% of patients.	8523336
Inflammation, Edema	Altered Intercellular Communication	The lesions was painless, with edema, inflammation and the presence of fistulae.	8525275
Airway structure, Asthma	Altered Intercellular Communication	Inhaled steroids have rendered an undoubtful benefit in the control of airway inflammation of the asthmatic patients.	8526176
Inflammation, Thrombosis, Arteriospasm	Altered Intercellular Communication	Treatment has been targeted at reducing arterial inflammation, arteriospasm and thrombosis.	8529683
Inflammation, Dissection of aorta, Necrosis, Arteritis, Infarction, Endarteritis, Cardiac Tamponade	Altered Intercellular Communication	Active arteritis with fibrinoid necrosis and obliterative endarteritis of vasa vasorum had resulted in multiple infarcts of differing ages with associated inflammation and disruption of the aortic wall, culminating in aortic dissection and cardiac tamponade.	8532387
Inflammation, Neoplasms, Necrosis	Altered Intercellular Communication	There was one patient whose differentiation from residual tumor or radiation-induced necrosis or inflammation on MRI was difficult.	8532506
Chronic inflammation, Ulcerative Colitis, Ulcer	Altered Intercellular Communication	Formalin-fixed paraffin-embedded sections of resected bowels from eight patients with UC and 20 with CD were reviewed, and blocks were selected having areas defined as follows: AI = two high-power fields (HPFs) at the edge of an ulcer, or one HPF with an inflamed crypt in the center; RM = branched or irregular glands with only mild chronic inflammation.	8532700
Arthritis	Altered Intercellular Communication	The acceptable accuracy of the method encourages further studies of the value of effusion and synovial membrane volumes as markers of the activity and/or severity of joint inflammation.	8533046
Inflammation	Altered Intercellular Communication	The IOP was higher elevated, however, and the bleb remained unchanged with severe conjunctival injection and aqueous inflammation.	8533645
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	These results suggest that human bronchial epithelial cells are capable of synthesizing RANTES and may therefore play an important role in the development of inflammation in allergic airways disease.	8534483
Airway structure	Altered Intercellular Communication	Furthermore, corticosteroids may prevent airway inflammation by downregulating the expression of proinflammatory cytokines in the bronchial epithelium.	8534483
Conjunctivitis	Altered Intercellular Communication	Seven patients were taking systemic immunosuppression and no patients had conjunctival inflammation for the 4 months before surgery.	8534641
Conjunctivitis	Altered Intercellular Communication	The surgery did not cause clinical activation of conjunctival inflammation or other complications.	8534641
Conjunctivitis	Altered Intercellular Communication	This technique gives good anatomical success over long periods and is particularly safe when there is no conjunctival inflammation present before surgery.	8534641
Chronic Kidney Diseases	Altered Intercellular Communication	Several hormonal alterations have been described in patients with chronic renal failure.	8534709
Coagulative necrosis, Blood Clot, Inflammation	Altered Intercellular Communication	Acute lesions showed superficial thrombus and early coagulation necrosis without inflammation.	8535560
Inflammation, Hemorrhage	Altered Intercellular Communication	Inflammation and hemorrhage could conceivably cause delayed effects of RF.	8535560
Inflammatory disease of mucous membrane, Acute ulcerative colitis	Altered Intercellular Communication	Plain X-ray films and air enema films reflect severe mucosal inflammation in acute ulcerative colitis.	8536825
Inflammation	Altered Intercellular Communication	There was a high specificity (0.86) when excluding inflammation in individual colon segments.	8536825
Inflammation	Altered Intercellular Communication	Air enema films underestimated the extent of inflammation in 8 of 16 patients compared to colonoscopy.	8536825
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In patients with ulcerative colitis (1) the presence of fecal residue and a normal air enema film exclude a friable or ulcerated mucosa with a high degree of certainty, and (2) the absence of fecal residue and an abnormal air enema film are predictors of the presence of endoscopically confirmed inflammation.	8536825
Inflammation, Squamous metaplasia	Altered Intercellular Communication	Rim enhancement does not correlate with the presence of squamous metaplasia, hemosiderin, or cholesterol within the cyst wall and is not consistently seen in cases with changes of mild, chronic inflammation.	8537515
Refractory anemias, Inflammation	Altered Intercellular Communication	Twenty patients (three men, 17 women; age range, 21-72 years) with clinically and radiologically proved RA underwent evaluation to define an MR imaging criterion for diagnosing synovial inflammation due to RA.	8539375
Inflammation, Angina, Unstable	Altered Intercellular Communication	Further studies are needed to elucidate the actual role of inflammation in unstable angina and its relation to activation of the coagulation system.	8540465
Inflammation	Altered Intercellular Communication	Laboratory tests yielded signs of chronic inflammation and impaired glucose tolerance with elevated serum insulin and glucagon concentrations.	8540523
Edema of eyelid, Erythema, Inflammation	Altered Intercellular Communication	Eyelid edema and erythema developed gradually in each patient, and maximal inflammation that prompted treatment was present at 12, 3, and 5 weeks, respectively, after surgery in the three patients.	8541263
Inflammation	Altered Intercellular Communication	In at least some cases, local corticosteroid injection may suppress the inflammation and permit retention of the implant.	8541263
Exudate	Altered Intercellular Communication	It is still not clear whether other constituents of the exudate, variable conditions of resorption, inflammatory conditions within the peritoneal lining, or the individual patient's capacity to limit the systemic response, may have a critical role.	8541423
Inflammation, Asthma	Altered Intercellular Communication	Airway responsiveness to bradykinin is related to eosinophilic inflammation in asthma.	8542147
Airway structure, Asthma	Altered Intercellular Communication	We investigated the relationship between airway inflammation and airway responsiveness, as assessed by PD15, to methacholine and to bradykinin in asthmatic patients.	8542147
Inflammation, Asthma	Altered Intercellular Communication	We conclude that in asthmatic patients, airway responsiveness to bradykinin but not to methacholine is related to the magnitude of eosinophilic inflammation in the airway mucosa.	8542147
Arthritis	Altered Intercellular Communication	Joints count: a review of old and new articular indices of joint inflammation.	8542200
Arthralgia, Exanthema, lupus-like syndrome	Altered Intercellular Communication	The anti-hypertensive agent hydralazine can cause a lupus-like syndrome characterized by serosal inflammation, arthralgias and rashes.	8542262
Granuloma, Inflammation	Altered Intercellular Communication	Neither granulomas nor suppurative inflammation were seen in all cases.	8542787
Inflammation, Colonization, Lymphocytic gastritis	Altered Intercellular Communication	These findings show a positive correlation between antral colonization by H. pylori and occurrence of lymphocytic gastritis, and suggest that the bacteria may have an important role in the induction of such particular form of antral inflammation.	8545561
Inflammation, Liver damage, Cholestasis	Altered Intercellular Communication	A correlation was found between changes in lymph node size and changes in markers of hepatocellular damage, cholestasis, and humoral immunoreactivity and also with intralobular inflammation.	8545610
Inflammation, Cholestasis	Altered Intercellular Communication	Changes in the size of the lymph nodes in the hepatoduodenal ligament may reflect inflammation and cholestasis in PBC and thus be a valuable indicator in the follow-up of patients with this disease.	8545610
Inflammation, Colonization	Altered Intercellular Communication	In the antrum the grade of chronic inflammation correlated positively with the grade of H. pylori colonization.	8545616
Inflammation, Gastritis	Altered Intercellular Communication	In cases of SG a low grade of colonization of H. pylori in the antral mucosa in connection with moderate inflammation predicted a reduction or even a healing of gastritis in the long term.	8545616
Inflammation	Altered Intercellular Communication	Collagenase concentrations in synovial fluid did not correlate with C reactive protein and collagenase levels in serum, but did correlate positively with the degree of synovial inflammation, and increased with increasing numbers of cells identified as expressing collagenase in synovial tissue.	8546529
Inflammation	Altered Intercellular Communication	The collagenase concentration in synovial fluid cannot be used as a marker for systemic disease activity, but can be used as a marker for the degree of synovial inflammation in the joint from which the sample is aspirated.	8546529
Menorrhagia, Blood Coagulation Disorders	Altered Intercellular Communication	The important clinical implication of this case is that the patient with adolescent menorrhagia may have an underlying coagulation disorder, which can successfully be managed by hormones.	8546661
Inflammation, Infiltration	Altered Intercellular Communication	The distinct pattern of T cell infiltration into sites of inflammation within the skin and synovium is regulated by both organ-specific homing and general inflammation-related mechanisms.	8546722
Inflammation, Perianal fistula, Intestines, Small, Specimen Source Codes - Abscess	Altered Intercellular Communication	Four parameters were shown by proportional hazards analysis to be independently associated with the risk for any stoma as well as a permanent one; increased risk coincided with rectal inflammation, perianal fistula or abscess, and absence of small intestinal involvement.	8548223
ARCN1 gene, Chronic Obstructive Airway Disease, Infiltration, Airway structure	Altered Intercellular Communication	Asthma and chronic obstructive pulmonary disease (COPD) are characterized by chronic airway inflammation with cell infiltration, increased plasma exudation and abnormal local secretion of proteins.	8548926
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	The ideal imaging method in inflammatory bowel disease would reliably detect inflammation, identify the correct intestinal location, and assess the severity of the disease.	8549945
Acute inflammation, Corneal edema	Altered Intercellular Communication	There was no difference between the groups in postoperative inflammation, corneal edema, intraocular pressure, or visual acuity.	8551453
Inflammation	Altered Intercellular Communication	Techniques involving radiolabelled leucocytes can pinpoint the site of inflammation.	8551884
Bacterial Infections, Arteritis	Altered Intercellular Communication	However, previous radiolabelling techniques have failed to distinguish between bacterial-mediated infection and non-bacterial inflammation.	8551884
Inflammation, Pleural Lymphoma, Empyema, Pleural	Altered Intercellular Communication	Longstanding inflammation in chronic pyothorax (CP) plays a role in the development of pleural lymphoma; therefore, in 1987, the term pyothorax-associated lymphoma (PAL) was proposed.	8552574
Intraocular inflammation, Cytomegalovirus, Uveitis	Altered Intercellular Communication	We prospectively examined 213 consecutive cases of general uveitis, defined as intraocular inflammation other than cytomegalovirus retinopathy, seen by a group of community-based comprehensive ophthalmologists.	8554079
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	MRI of the brain showed a hypertensive type lesion in T2, in the right pontomedullary region that suggested inflammation.	8554785
Inflammation, Mass of pancreas, Ulcer	Altered Intercellular Communication	However, resection of the pancreatic mass could not be performed owing to severe inflammation around the duodenum, probably induced by the postbulbar duodenal ulcers.	8555708
Inflammation, Tuberculosis	Altered Intercellular Communication	The histologic diagnosis following thoracoscopic biopsy in 13 patients showed non-specific inflammation in 12 cases and tuberculosis in one case.	8556926
Mastitis, Communicable Diseases	Altered Intercellular Communication	To exclude other causes of breast inflammation, patients were required to have histologic or aspiration results specific for infection.	8557497
Inflammation, Chronic gastritis	Altered Intercellular Communication	Twenty (64.5%) patients had chronic active gastritis and tested positive for H pylori organism, 5 (16.1%) were normal, 5 (16.1%) had inflammation but were negative for H pylori, and 1 (3.2%) had an insufficient amount of tissue.	8557514
Inflammation	Altered Intercellular Communication	Initial biopsies showed demyelination with axonal sparing in two, non-specific inflammation in one, and normal brain in one.	8558135
Necrotizing granulomatous inflammation, Inflammation, Glomerulonephritis	Altered Intercellular Communication	The pathological study showed a crescentic glomerulonephritis, a chronic granulomatous inflammation in the lungs and in the nasal mucosa, an acute nonspecific inflammation or a chronic granulomatous inflammation and focal blood vessel fibrinoid necrosis.	8560115
Inflammation	Altered Intercellular Communication	There was evidence that the degree of inflammation in the mucosa was related to the numbers of H. pylori-like organisms (HPLO) present.	8560523
Inflammation, Helicobacter-associated gastritis	Altered Intercellular Communication	We defined the 'gold standard' of H. pylori-associated gastritis as the presence of both moderate to numerous HPLO and moderate to severe inflammation in the gastric mucosa.	8560523
Gastric mucosa, Helicobacter pylori, Inflammation, Gastritis, Atrophic	Altered Intercellular Communication	The association between the topographic distribution of Helicobacter pylori colonization, inflammation and atrophy of the gastric mucosa, and fasting gastric pH was studied in a population with high prevalence of multifocal atrophic gastritis.	8561094
Inflammation, Atrophic	Altered Intercellular Communication	However, after therapeutic eradication of H pylori, inflammation subsided and gastric pH decreased indicating improved acid secretion despite persistent atrophy.	8561094
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Liver histology showed diffuse steatosis and parenchymal inflammation in all cases, with concomitant fibrosis and Mallory bodies in three of them.	8563007
Airway structure, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Interleukin-8 in airway inflammation in patients with asthma and chronic obstructive pulmonary disease.	8563494
ARCN1 gene, Airway structure, Chronic Obstructive Airway Disease, Lung Diseases, Obstructive, Asthma	Altered Intercellular Communication	We have investigated whether IL-8 is present in airway secretions from patients with asthma and chronic obstructive pulmonary disease (COPD) to obtain information on its possible role in airway inflammation in obstructive airways disease.	8563494
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Asthma and chronic obstructive pulmonary disease are characterized by chronic airway inflammation.	8564092
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	We investigated whether induced sputum was a useful method of studying airway fluid from patients with moderate to severe COPD and whether it could be used to compare inflammation in this condition with that in asthma.	8564092
ARCN1 gene, Inflammation	Altered Intercellular Communication	We conclude that the cytokines TNF alpha and IL-8 may be involved in the inflammation in COPD.	8564092
Airway structure	Altered Intercellular Communication	Sputum examination is a useful noninvasive method to study airway inflammation.	8564094
Necrotizing granulomatous inflammation, Amoeba genus	Altered Intercellular Communication	Histologic examination revealed necrotizing granulomatous inflammation with numerous amebic organisms that were cultured and identified as Acanthamoeba group 2, probably Acanthamoeba castellani by monoclonal antibodies.	8565615
Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The relationship between GM and gastroduodenal inflammation and H. pylori infection density was also studied.	8566592
Gastritis, Ulcer	Altered Intercellular Communication	Ulcer healing alone produced no change in GM or in gastroduodenal inflammation.	8566592
Inflammation	Altered Intercellular Communication	H. pylori eradication produced a 42% reduction in GM and improvement in inflammation.	8566592
Microalbuminuria, "Crohns disease of large bowel", Ulcerative Colitis, Colitis	Altered Intercellular Communication	In conclusion, the strong correlation of microalbuminuria with a standard intestinal histopathological grading system suggests that microalbuminuria accurately reflects the severity of colonic inflammation in patients with Crohn's colitis and ulcerative colitis.	8566867
Autoimmune Diseases of the Nervous System, MS gene	Altered Intercellular Communication	In the present study, observations previously made in animal models of autoimmune central nervous system inflammation have been extended to the analysis of multiple sclerosis (MS) lesions.	8567065
Upper Respiratory Infections	Altered Intercellular Communication	It has been reported that secretory leukoprotease inhibitor (SLPI) can be a useful indicator for acute respiratory tract inflammation.	8569039
Inflammation	Altered Intercellular Communication	These results suggest that SLPI may be a useful indicator for local inflammation in respiratory tract.	8569039
Chronic Actinic Dermatitis	Altered Intercellular Communication	The action spectrum for induction of chronic actinic dermatitis is similar to that for sunburn inflammation.	8570744
Inflammation, Trichomonas Infections, Candidiasis	Altered Intercellular Communication	The presence of candidiasis and trichomoniasis was highly associated with abnormal cytologic findings, particularly those indicative of inflammation.	8570805
Airway structure, Sinobronchial syndrome	Altered Intercellular Communication	It has been established that long-term low-dose erythromycin therapy (EM therapy) is very effective for sinobronchial syndrome, a common condition in Japan characterized by chronic upper and lower airway inflammation.	8570882
Percutaneous transhepatic cholangiography, Kidney Failure	Altered Intercellular Communication	Age-related hormonal insufficiency contributes to the onset of PTC.	8571488
Inflammation, Arthropathy	Altered Intercellular Communication	To analyse synovial fluid and serum concentrations of the amino-propeptide of the type III procollagen (PIIINP) in normal individuals and patients with joint disease, and to explore the relationship between synovial fluid PIIINP concentrations and the rheumatological diagnosis, local inflammation, and joint disease.	8572734
Inflammation, Keratoconus, Corneal edema, Ulcer	Altered Intercellular Communication	The leading indications, in order of decreasing frequency, were pseudophakic corneal edema (24.8%), regrafts (21.3%), scarring with or without chronic inflammation (11.1%), keratoconus (7.1%), aphakic corneal edema (6.4%), and ulcerative conditions (5.8%).	8575177
Airway structure, Asthma	Altered Intercellular Communication	The role of airway inflammation in the pathogenesis of asthma in childhood is uncertain.	8575573
Airway structure	Altered Intercellular Communication	The results of this study suggest that immunoglobulin E (IgE)- and non-IgE-mediated airway inflammation are important in exercise- and methacholine-induced bronchoconstriction in children with recurrent wheeze, although it is probable that different mechanisms are responsible.	8575573
Airway structure	Altered Intercellular Communication	Cyclooxygenase products are released by chronic airway inflammation.	8575575
Inflammation, Gastritis, Helicobacter-associated gastritis, Hypergastrinemia (finding), Somatotropin deficiency	Altered Intercellular Communication	These results suggest that hypergastrinemia in H. pylori gastritis is not caused by antral gastritis and antral somatostatin deficiency alone but that corpus inflammation plays a key role in the origin of hypergastrinemia.	8578165
Inflammation	Altered Intercellular Communication	Eradication of the bacterium led to a significant improvement in semiquantitative histology scores; active antral inflammation decreased from (mean +/- SEM) 1.84 +/- 0.19 to 0.21 +/- 0.16 (p = 0.0004) and chronic antral inflammation from 2.47 +/- 0.14 to 1.16 +/- 0.14 (p = 0.0002); active gastric body inflammation decreased from 0.95 +/- 0.19 to 0.00 +/- 0.00 (p = 0.0015) and chronic inflammation from 1.68 +/- 0.17 to 0.32 +/- 0.11 (p = 0.0007).	8578230
Inflammation, Granulomatous mediastinitis	Altered Intercellular Communication	The chronic inflammation in this case suggested granulomatous mediastinitis, a rare disease whose mass-like effects may contribute to structural compression.	8578362
Inflammation, Hemorrhage, Calcinosis	Altered Intercellular Communication	Chronic inflammation leading to calcification and broncholith may invade bronchial lumen or esophageal wall, causing life-threatening hemorrhage and necessitating prompt surgical intervention.	8578362
Inflammation, Atherosclerosis	Altered Intercellular Communication	Modern techniques of investigation have revealed several similarities between atherosclerosis and chronic inflammation, and that immune mechanisms seem to operate in the incipient and subsequent phases of atherosclerosis.	8581143
Inflammation, Hemorrhage, Gingiva red	Altered Intercellular Communication	Post-therapy, the poor response group exhibited the greatest degree of gingival inflammation as assessed by gingival redness and bleeding on probing.	8583020
Inflammation, Nonunion of Bone	Altered Intercellular Communication	During that period there was no sign of inflammation, and there were no nonunions.	8583053
Inflammation, Neoplasms	Altered Intercellular Communication	He had inhaled a fibrinolysin-deoxyribonuclease mixture (Elase) to treat inflammation in the oral cavity after resection of an oral tumor.	8583726
Amaurosis, Adenoiditis, Inflammation	Altered Intercellular Communication	A bilateral amaurosis with descending opticus atrophy as a consequence of a sphenoiditis and spreading inflammation to the meninges and the optic nerve in the area of the chiasm is a rare event.	8583751
Airway structure, Respiratory Hypersensitivity, Obstruction	Altered Intercellular Communication	The lack of symptoms in the children with airway hyperresponsiveness could be due to an insufficient stimulus to cause symptomatic obstruction, or the absence of eosinophilic airway inflammation, which may be a requirement for the development of symptomatic airway hyperresponsiveness.	8586130
Inflammation, Egg Food Product, Granuloma	Altered Intercellular Communication	In addition, endoscopic biopsies from all patients were examined for the presence of inflammation, parasite eggs, granulomas and mucosal vascular congestion.	8586365
Inflammation	Altered Intercellular Communication	Moreover, the scores of synovial uptake correlated significantly with systemic variables of inflammation.	8587071
Refractory anemias, Arthritis	Altered Intercellular Communication	Although nonspecific for RA, 99mTc IgG scintigraphy is a reliable tool to evaluate the degree and extent of joint inflammation.	8587071
Inflammation, Retinal Detachment, Cataract, Traumatic injury, Primary glaucoma, Intraocular Route of Drug Administration, Disease	Altered Intercellular Communication	The most frequent underlying ocular diseases were: intraocular tumour (47.7%), surgical disease [primary glaucoma, retinal detachment, cataract] (18.6%), trauma [enucleation within 4 weeks after the event] (10.3%), systemic disease (6.6%), inflammation (6.1%), other diseases (10.7%).	8587305
Inflammation, Tuberculosis, Pulmonary, Traumatic injury, Intraocular Route of Drug Administration, Glaucoma, CTCAE	Altered Intercellular Communication	The final causes for enucleation were: intraocular tumour (46.4%), secondary glaucoma (31.6%), atrophia and phthisis bulbi (11.9%), inflammation (6.5%), trauma (0.9%), other diseases (2.7%).	8587305
Inflammation, Carcinoma, Spindle-Cell, Carcinoma	Altered Intercellular Communication	To describe an unusual type of vesical carcinoma (sarcomatoid carcinoma) associated with the spread of inflammation.	8588725
Inflammation, Carcinoma, Spindle-Cell, Lymphoma	Altered Intercellular Communication	We describe a patient with vesical sarcomatoid carcinoma associated with the spread of inflammation that practically obscured the undifferentiated area, mimicking a lymphoma.	8588725
Inflammation	Altered Intercellular Communication	The peculiarity of the case resides in the associated spread of inflammation which improved the prognosis.	8588725
HD Term Type, Inflammation	Altered Intercellular Communication	Because L-selectin is important for leukocyte attachment to endothelium at sites of inflammation, alterations of shed L-selectin and cell-surface L-selectin levels may play a role in the immunologic consequences of HD treatment.	8589321
Peripheral T-Cell Lymphoma, Hemophagocytic histiocytosis	Altered Intercellular Communication	Peripheral-T-cell lymphoma with hemophagocytic histiocytosis localised to the bone marrow associated with inappropriate secretion of antidiuretic hormone.	8590855
Inflammation, Sequela of disorder	Altered Intercellular Communication	Non-neoplastic lesions were mainly functional cysts or sequellae of inflammation.	8591636
Inflammation, Thrombophilia	Altered Intercellular Communication	Antibiotic chemotherapy and the administration of gebexate mesilate improved the inflammation and hypercoagulable state.	8591715
Chronic disease	Altered Intercellular Communication	Advanced age and chronic illness in our patients may have played a role in limiting the hormonal response reported by others.	8593965
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Inflammatory cytokines have been implicated as important mediators of inflammation in rheumatoid arthritis (RA).	8596138
Inflammation, Ischemia	Altered Intercellular Communication	Bowel wall thickening: differentiation of inflammation from ischemia with color Doppler and duplex US.	8596864
Ischemia, Inflammation	Altered Intercellular Communication	Absence of or barely visible color Doppler flow and absence of arterial signal suggested ischemia; readily visible color Doppler flow and a stratified echotexture suggested inflammation.	8596864
Inflammation	Altered Intercellular Communication	A resistive index less than 0.60 indicated inflammation.	8596864
Inflammation	Altered Intercellular Communication	These preliminary data suggest a role for power Doppler sonography in assessment of serial changes in synovial inflammation.	8596870
Inflammation, Plasmacytoma, Hematological Disease	Altered Intercellular Communication	The sensitivity of hemopoietic bone marrow to magnetization transfer is analyzed in 15 healthy volunteers and seven patients with different hematological disorders (inflammation, plasmacytoma, hemopoietic reconstitution after bone marrow transplantation).	8598806
Rupture	Altered Intercellular Communication	Sebaceous glandular inflammation, eosinophilic pustule formation, and follicular rupture were present in less than half of the biopsies.	8599447
Inflammation	Altered Intercellular Communication	The strong inflammation along the epidermal-dermal junction due to unknown factors may have modified the clinical appearance and the histopathology.	8599459
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	It is concluded that in patients with active ulcerative colitis, inflammation is better visualized with 99mTc-exametazime labelled leucocytes than with 99mTc-labelled antigranulocyte antibodies.	8599955
Colitis	Altered Intercellular Communication	The antibody technique offers the advantage of in vivo labelling, but is less reliable than the exametazime method for imaging of colonic inflammation.	8599955
Fibrous, selenium, Inflammation	Altered Intercellular Communication	The results of linear discriminant analysis showed that inflammatory changes in fibrous septa were significantly more pronounced in cases with RHAs on MR. RHAs seen on T2WI SE images may correspond to fibrous septa with inflammation.	8600962
Inflammation, selenium, Liver Cirrhosis	Altered Intercellular Communication	The signal intensity of fibrous septa surrounding regenerative nodules on T2WI SE images may be increased in liver cirrhosis due to inflammation or vascular dilation, contributing to the visualization of regenerating nodules as relatively low-intensity regions on MR.	8600962
Inflammation, Refractory anemias, Rheumatoid Arthritis, Musculoskeletal Pain, Temporal Arteritis	Altered Intercellular Communication	The inflammation of the rheumatoid arthritis (RA), polymyalgia rheumatica, and temporal arteritis can be assessed by the erythrocyte sedimentation rate (ESR).	8604722
Inflammation	Altered Intercellular Communication	The C-reactive protein (CRP, an acute-phase protein) test, which is newer, correlates more closely than ESR with clinical and radiographic parameters of RA inflammation.	8604722
Superficial ulcer, Arthritis, Rheumatoid Factor	Altered Intercellular Communication	High titers of rheumatoid factor are associated with progressive joint inflammation, erosions, and disability.	8604722
Crohn Disease	Altered Intercellular Communication	During the past decade, the aim of surgery for Crohn's disease has shifted from radical operation, achieving inflammation-free margins of resection, to "minimal surgery," intended to remove just grossly inflamed tissue or performing strictureplasties.	8604905
Inflammation, Perianal fistula	Altered Intercellular Communication	Young age at onset, duodenal and jejunal involvement, presence of enterocutaneous or perianal fistula, and a single surgeon (of 23) were associated significantly with increased risk of regional recurrence but not strictureplasty or inflammation at margins of resection.	8604905
Infarction, Inflammation, Thrombosis, Intraductal Hyperplasia	Altered Intercellular Communication	For reasons given, the primary cause of the initial ductal blockage that results in PIN and PCA cannot be inflammation, stones, proteineous plugs, infarction, venus thrombosis, ductal hyperplasia, nor a constricted penis at ejaculation.	8606875
Hepatitis A, Portal inflammation	Altered Intercellular Communication	Two patients had portal inflammation on 3-month biopsies consistent with viral hepatitis.	8607170
Inflammation, Hepatobiliary Disorder, Primary Biliary Cholangitis	Altered Intercellular Communication	These findings suggest that methotrexate treatment in patients with primary biliary cirrhosis is not beneficial in patients with advanced disease; in patients with early disease, methotrexate may be associated with amelioration of symptoms, reduction in serum biochemical indices of liver disease, and reduction in hepatic inflammation.	8607496
Airway structure, airway disease	Altered Intercellular Communication	Our results suggest that the relative amounts of IL-1beta and IL-1Ra or IL-8 may contribute, at least in part, to the neutrophil-mediated chronic airway inflammation in patients with chronic airway disease, and long-term erythromycin therapy may down-regulate the vigorous cycle between the cytokine network and neutrophil accumulation, with resultant reduction of neutrophil-mediated inflammatory response.	8608647
Inflammation, Neoplasms	Altered Intercellular Communication	STn antigen appearance preceded the detection of neoplasia by 7 or fewer years, and its preferential expression in patients was not confounded by the degree of active inflammation.	8608878
Inflammation, Duodenal Ulcer	Altered Intercellular Communication	Histological examination of duodenal biopsy samples was comparable in patients with duodenal ulcers and normal subjects without apparent relationship between inflammation and DMBS.	8608879
Inflammation	Altered Intercellular Communication	According to these, nevi excised in summer show a higher mitotic count, a greater extent of the junctional component, and more frequent regression and inflammation.	8609260
Inflammation	Altered Intercellular Communication	The role of endothelial vascular cell adhesion molecule-1 (VCAM-1) in the trafficking of lymphocytes from the vascular circulation through endothelium and into sites of filarial inflammation was investigated in asymptomatic microfilaremic (MF; n = 16) and in patients with filaria-associated lymphatic pathology (LP; n = 23).	8609410
Inflammation, Prostatic Intraepithelial Neoplasias	Altered Intercellular Communication	Likewise, a statistically significant correlation between PAP levels and patient age, patient race, severe inflammation, of high grade prostatic intraepithelial neoplasia (PIN) was not found.	8610055
Lung Diseases, Interstitial, Pneumonitis	Altered Intercellular Communication	DTPA clearance a measure of lung inflammation, and HRCT paralleled clinical course during the treatment of interstitial lung disease.	8612030
Euthyroid Sick Syndromes, hormone deficiency, Immune System Diseases	Altered Intercellular Communication	These observations point toward a potential for TRH as a strategy for reversing the euthyroid sick syndrome, growth hormone deficiency, and immune dysfunction associated with critical illness.	8612408
Hormone abnormality, Hypertension, CTCAE, Obesity	Altered Intercellular Communication	Once the latent cortisol excess has been eliminated, those symptoms which are due to hormonal abnormality may regress, but nonspecific signs, such as obesity or hypertension, may not necessarily improve.	8612460
Inflammation, Dental Plaque	Altered Intercellular Communication	12 patients out of these demonstrated clinically significant overgrowth and their plaque scores and gingival inflammation were greater than for the non-overgrowth group (p < 0.001).	8613563
Airway structure	Altered Intercellular Communication	Urinary leukotriene E4 (LTE4) is a marker of the body's production of cysteinyl LTs, important mediators of airway inflammation.	8613628
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Variability estimates for the indexes other than serum iron concentration and transferrin saturation were not altered by the inflammation of rheumatoid arthritis.	8613658
Multiple Organ Failure, Inflammation, MORM syndrome, Infection	Altered Intercellular Communication	Better understanding of the relative roles of the dysfunctional inflammation and infections in early MOF versus late MOF may facilitate the development of new strategies for the prevention and treatment of morbid syndrome.	8614027
Inflammation, Keratinization, function	Altered Intercellular Communication	In vitro and in vivo investigations have shown interference of these compounds with epidermal growth, keratinisation and inflammation.	8615058
Inflammation, Prolactinoma, Craniopharyngioma, Neoplasms	Altered Intercellular Communication	In all of these patients the inflammation originated from an additional tumor in the sellar region (4 craniopharyngiomas, 1 prolactinoma).	8615086
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Based on our results and three other cases reported in the literature so far, we think that the presently used classification of pituitary inflammatory diseases lacks an entity which describes a non-abscess-forming inflammation of the pituitary gland originating from an associated pathological process.	8615086
Inflammation, Atherosclerosis	Altered Intercellular Communication	The body's response to inflammation may play an important part in influencing the progression of atherosclerosis.	8616412
Inflammation, Irritation - emotion	Altered Intercellular Communication	In our study population, linear basal staining for p53 and strong staining for cyclin D1 had higher specificity for progression than did EGFR overexpression, which was also seen in association with inflammation and chronic irritation.	8616872
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Portal/periportal inflammation was the same in all groups; however, lobular inflammation and fibrosis were more severe in patients with persistent HBV infections and in those with acquired HBV and HCV coinfections.	8617417
Malignant - descriptor, Inflammation	Altered Intercellular Communication	These findings might be explained by nonspecific recruitment of malignant T cells to sites of local inflammation mediated by non-neoplastic antigen-specific T cells.	8618005
Necrotizing granulomatous inflammation	Altered Intercellular Communication	A visible edge despite intense staining in the late phases of a fluorescein angiogram may suggest the possibility of subretinal granulomatous inflammation in a lesion that otherwise appears like a neovascular membrane.	8618756
Necrotizing granulomatous inflammation, Unknown (origin) (qualifier value)	Altered Intercellular Communication	The clinical distinction between this pattern of subretinal neovascularization and a typical idiopathic membrane may be important because subretinal granulomatous inflammation could respond to treatment with systemic corticosteroids.	8618756
Inflammation, Unspecified visual loss	Altered Intercellular Communication	Patients with MCP had visual loss and visual field defects caused directly by visible lesions or recurrent inflammation around old lesions.	8618760
Inflammation, Multiple Evanescent White Dot Syndrome	Altered Intercellular Communication	Patients with MEWDS had the least inflammation with symmetrically distributed lesions.	8618760
Crohn Disease, Strongyloidiasis, Ulcerative Colitis, Eosinophilic inflammation	Altered Intercellular Communication	In contrast to the usual Strongyloides hyperinfection syndrome, in which small intestinal and pulmonary manifestations are seen in patients with some forms of immunodeficiency, the patients described here presented with only a characteristic transmural eosinophilic granulomatous inflammation affecting mostly the colonic wall and clinically mimicking ulcerative colitis or Crohn's disease.	8619425
Cardiovascular Physiological Phenomena	Altered Intercellular Communication	Endothelin is involved in the control of cardiovascular and renal functions and acts as a neuromodulator.	8619715
Inflammation, Asthma	Altered Intercellular Communication	Cetirizine reduces ICAM-I on epithelial cells during nasal minimal persistent inflammation in asymptomatic children with mite-allergic asthma.	8620097
House dust mite allergy, Inflammatory disease of mucous membrane	Altered Intercellular Communication	It has been recently demonstrated that individuals who suffer from mite allergy present mucosal inflammation even when asymptomatic.	8620097
House dust mite allergy, Inflammation	Altered Intercellular Communication	It has been called 'minimal persistent inflammation' (MPI) for its relationship with natural exposure to allergen, which is continuous in the case of mite allergy.	8620097
Inflammation, Specimen Type - Fistula	Altered Intercellular Communication	Cautious surgery for fistula when rectal inflammation is quiescent is worthwhile.	8620778
Herpes Zoster Ophthalmicus, Complication Aspects, Inflammation, Uveitis	Altered Intercellular Communication	Herpetic uveitis is a serious ocular disease in which recurrence of inflammation results in severe ocular complications.	8620818
Inflammation, Idiopathic Pulmonary Fibrosis, Disease	Altered Intercellular Communication	Idiopathic pulmonary fibrosis (IPF) is a progressive disorder characterized by inflammation, fibroblast proliferation, and accumulation of extracellular matrix proteins.	8621765
Inflammation, Fibrosis Assessment, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	IPF homogenate levels of LTB(4) were significantly correlated with histologic indices of both inflammation (r=0.861) and fibrosis (r=0.926).	8621765
Airway structure, Asthma	Altered Intercellular Communication	Some patients with asthma respond poorly to corticosteroids and have persistent airway inflammation and daily clinical symptoms.	8621845
Inflammation	Altered Intercellular Communication	NF-kappa B may regulate the production of cytokines at the site of synovial inflammation.	8624487
Inflammation	Altered Intercellular Communication	However, if one considers the presence of chronic inflammation, normal plasma ACTH and cortisol concentrations must be considered as inappropriately low.	8624638
Inflammation	Altered Intercellular Communication	Eight patients underwent CT scan, but only in one case did CT findings lead to a clear definition of a bulky inflammation process of the chest.	8624789
Malignant neoplasm of endometrium	Altered Intercellular Communication	Determination of EGF sensitivity on a receptor and a functional level may provide important additional information about the hormonal sensitivity of endometrial cancer.	8625080
Airway structure	Altered Intercellular Communication	Coughing was studied in relation to different disorders and objective variables indicative of airway inflammation.	8625678
Inflammation	Altered Intercellular Communication	We report two patients with transient MRI abnormalities, suggesting transient inflammation of the trigeminal nerve caused temporary facial sensory symptoms.	8628500
Inflammation	Altered Intercellular Communication	Surgery performed while there were signs of pericoronal inflammation also resulted in more complications.	8628837
Arthritis	Altered Intercellular Communication	Patients with evidence of active joint inflammation also require prompt evaluation.	8629573
Inflammation, Fibrosis Assessment, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Small amounts of matrix-associated TGF-beta 1 were present subepithelially in areas of lung sections from patients with IPF with minimal inflammation and no fibrosis.	8630262
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In normal lungs with no evidence of inflammation or fibrosis TGF-beta 1 was not seen in alveolar macrophages, epithelial cells, or extracellularly.	8630262
Inflammation	Altered Intercellular Communication	Our observations suggest that altered inflammatory cell profiles and low-grade inflammation exist in the lower respiratory tracts of many asymptomatic, clinically normal volunteers of advanced age.	8630547
Respiratory Distress Syndrome, Adult, Pneumonitis	Altered Intercellular Communication	These results suggest that NO inhalation might reduce lung inflammation in ARDS, as reflected by PMN activation status and IL-8/IL-6 release.	8630584
Pain Distress Question, Inflammation	Altered Intercellular Communication	Arthroscopy, which has been used extensively to decrease pain and inflammation and increase the range of motion, has recently been challenged as the treatment of choice.	8631648
Inflammation	Altered Intercellular Communication	Changes in signal intensity were specific for SS and did not occur with parotid inflammation.	8633469
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Upper GI mucosal inflammation was present in all patients.	8633507
Nonulcer dyspepsia, Communicable Diseases, Inflammation, Inflammatory disease of mucous membrane	Altered Intercellular Communication	In patients with non-ulcer dyspepsia, we assessed the link between Hp infection and gastric mucosal inflammation, as well as the influence of Hp and inflammation on the serum levels of anti-Hp antibodies (IgG), pepsinogen A (PGA), pepsinogen C (PGC), and gastrin.	8633587
Communicable Diseases, Nonulcer dyspepsia, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Hp infection, frequently found in patients with non-ulcer dyspepsia, is associated with gastric mucosal inflammation; of the indices studied, serum IgG and PGC most accurately indicated Hp infection, and their product may be proposed as an aid in diagnosing Hp infection in dyspeptic patients.	8633587
Inflammation, Helicobacter pylori Positive, Atrophic, Chronic gastritis	Altered Intercellular Communication	Distribution of inflammation and atrophy in the stomach of Helicobacter pylori-positive and -negative patients with chronic gastritis.	8633589
Inflammation, Helicobacter pylori Positive, Atrophic, Chronic gastritis	Altered Intercellular Communication	To investigate the extent of inflammation and atrophy in the stomach of Helicobacter pylori-positive and -negative patients with chronic gastritis.	8633589
Intestinal metaplasia, Inflammation, Gland	Altered Intercellular Communication	The histological severity of chronic and acute inflammation, glandular atrophy, and intestinal metaplasia was assessed according to the Sydney system.	8633589
Inflammation, Gastritis, Atrophic	Altered Intercellular Communication	The severity of acute and chronic inflammation at the greater curvature of the body increased with the extension of atrophic gastritis.	8633589
Inflammation, Gastritis, Gastritis, Atrophic	Altered Intercellular Communication	In H. pylori-negative patients, the severity of chronic inflammation at the greater curvature of the body was significantly higher in patients with extensive atrophic gastritis than in those with a lesser extent of atrophic gastritis.	8633589
Inflammation, Atrophic	Altered Intercellular Communication	At the greater curvature of the body, the development of atrophy is closely associated with the increase in the severity of inflammation, which is more marked in H. pylori-positive patients.	8633589
Inflammation	Altered Intercellular Communication	Oligoclonality in the CD8 repertoire persisted despite successful control of the disease activity, suggesting that the CD8+ clonotypes are not an epiphenomenon of the inflammation.	8635285
Inflammation, Attachment (action)	Altered Intercellular Communication	The adult Kenyan and the adult Chinese group, who had very poor oral hygiene conditions and massive gingival inflammation, had attachment loss levels which were quite similar to those in a Japanese population (31), in a Norwegian population (27) and in a New Mexico group of adults (30).	8636871
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	Inflammation-induced articular cartilage degradation is a major problem in rheumatoid arthritis (RA).	8639180
Glomerulonephritis, Acute infectious disease	Altered Intercellular Communication	The acute IL-1 alpha creatinine quotients were lowest in children with uptake defects on 99mTC-dimercaptosuccinic acid (DMSA) scintigraphy both during the acute infection (reflecting the acute inflammation) (p < 0.001) and 1 year after the acute infection (reflecting permanent kidney scarring) (p < 0.001).	8640042
Nephritis	Altered Intercellular Communication	In conclusion, persisting high urinary levels of IL-1 alpha were associated with less renal inflammation and scarring.	8640042
Nephritis	Altered Intercellular Communication	This unusual type of renal inflammation has a typical clinical picture that is important to bear in mind.	8640064
Inflammation, Ear Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	Allergy may play a role in the middle ear inflammation that leads to otitis media with effusion.	8643262
Communicable Diseases, Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	The purpose of this study was to determine whether an elevated mediator correlated with the patient's disease and thus could be used to differentiate allergy vs. infection as the cause of the middle ear inflammation.	8643262
Inflammation, Ear Inflammation	Altered Intercellular Communication	Significantly elevated levels of both eosinophil cationic protein and myeloperoxidase indicated that inflammation in the ear of patients with otitis media with effusion was characterized by a pronounced involvement of both eosinophils and neutrophils.	8643262
Inflammation	Altered Intercellular Communication	SDF from PODs 0 and 1 also showed marked EC chemotactic activity and stimulated rapid formation of new vessels without signs of inflammation when implanted into rat corneas.	8644013
Inflammation, Pancreatitis	Altered Intercellular Communication	Four (6.6%) were benign lesions which included nonspecific inflammation (2 cases), tuberculous pancreatitis (1) and pseudopancreatic cyst (1).	8644357
Kimura Disease	Altered Intercellular Communication	Kimura's disease is a chronic inflammatory condition of unknown etiology.	8644388
Intraocular inflammation	Altered Intercellular Communication	Over a 4-week period of observation, the choroidal lesions appeared to enlarge slowly and increased in number in the posterior pole, with no clinical evidence of intraocular inflammation and retinal involvement.	8644534
Inflammation, Peritonitis, Pelvic abscess, Acute inflammation, Mesenteric abscess	Altered Intercellular Communication	Patients were categorized according to the following pathologic stages: stage 0, no inflammation; stage I, chronic inflammation; stage II, acute inflammation with or without microabscesses; stage III, pericolonic or mesenteric abscess; stage IV, pelvic abscess; and stage V, purulent or feculent peritonitis.	8645067
Inflammation	Altered Intercellular Communication	The most important parameter in determining the feasibility of attempting laparoscopic cholecystectomy in the setting of acute inflammation appears to be the experience of the surgeon.	8646025
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Vascular cell adhesion molecules (VCAM) play an important part in the regulation of inflammation and are considered to be important in the process of malignant tumour growth.	8646365
Inflammation, Cartilage damage, Refractory anemias, Swelling, Sore to touch	Altered Intercellular Communication	Local signs of joint inflammation (tenderness, swelling, "ballottement') and range of motion (ROM) were scored and the sum, taken as a global outcome measure, was recorded in 17 RA and 18 PsA knees, both before and at follow-up periods of 2, 6, 12, 24 and 36 months after surgical AS (knee joint synovectomy; meniscal curettage, cartilage shaving or chondrectomy, according to the degree of cartilage damage).	8646438
Pain Distress Question, Arthritis	Altered Intercellular Communication	No intra- or post-operative morbidity, pain worsening or loss of joint motion was observed and all patients were discharged within 48 h. Comparison of the parameters of knee joint evaluation showed a significant reduction of the signs of joint inflammation and a significant increase in the ROM in all follow-up periods.	8646438
Refractory anemias, Inflammation, PROS1 gene	Altered Intercellular Communication	Our study indicates that AS synovectomy is a safe procedure requiring short hospitalization which, in combination with second-line medical treatment, can reduce local inflammation in RA and PsA KJS, and preserve knee joint ROM for up to 3 yr.	8646438
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	We have used a novel leukocyte adhesiveness/aggregation test (LAAT) to show that many patients with inflammatory bowel disease (IBD) in clinical remission have a subclinical low grade inflammation.	8646948
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Identification of patients with IBD in clinical remission who have ongoing inflammation may be of clinical-therapeutic relevance.	8646948
Inflammation	Altered Intercellular Communication	He had inflammation of the proximal nail folds and arrested nail growth of digits 3, 4 and 5 on the right hand.	8647704
Inflammation	Altered Intercellular Communication	The inflammation calmed down, and a significant improvement of vision was noted at dismissal.	8648986
Gingivitis, Primary malignant neoplasm, Dental caries	Altered Intercellular Communication	Intensive prophylactic dental care after cancer treatment is important in order to prevent caries and gingival inflammation.	8649317
Inflammation, Allergy - Charge Type Reason, Decompensated, Virus Diseases, Endolymphatic Hydrops, Hypersensitivity	Altered Intercellular Communication	At least three mechanisms by which allergy may play a role in the production of fluid in the endolymphatic sac are described: the endolymphatic sac itself might be a "target organ" of mediator released from systemic inhalant or food reactions; deposition of circulating immune complex may produce inflammation and interfere with the sac's filtering capability; and a predisposing viral infection in childhood that produces a mild impairment of endolymphatic sac function may interact with allergies in adulthood and cause the endolymphatic sac to decompensate, resulting in endolymphatic hydrops.	8649868
Inflammation, Virus Diseases, Primary cardiac lymphoma, Pleural Lymphoma	Altered Intercellular Communication	These findings suggest that primary cardiac lymphoma, unlike pyothorax-associated pleural lymphoma, appears to have no association with chronic inflammation or Epstein-Barr virus infection.	8651857
Refractory anemias, Inflammation	Altered Intercellular Communication	The presence of clonal outgrowth of selected CD4+ T cells specificities in unaffected siblings of RA patients suggests that oligoclonality of CD4+ T cells is inherited and is a risk factor for, rather than a result of, synovial inflammation.	8651983
Chronic inflammation, Endometriosis	Altered Intercellular Communication	During laparoscopy or laparotomy peritoneal fluid and serum were collected from 29 patients with endometriosis, 31 patients with benign ovarian masses and 4 patients with chronic inflammation or adhesions.	8653926
Disease, Endometriosis	Altered Intercellular Communication	Patients with endometriosis stage IV revealed slightly higher IL-6 concentrations in peritoneal fluid when compared to patients with stage I to II disease and ovarian masses/ chronic inflammation.	8653926
Ovarian Cysts, Inflammation, Endometriosis	Altered Intercellular Communication	Patients with endometriosis revealed significantly higher sIL-6 receptor concentrations in peritoneal fluid and serum as compared to patients with ovarian cysts and chronic inflammation.	8653926
Inflammation	Altered Intercellular Communication	The degree of inflammation on air enema films and the extent of histopathological ulceration in colectomy specimens were independently graded and compared with each other.	8656906
Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	FINDINGS The degree of inflammation on air enema radiography correlated significantly with depth of ulceration at histopathological examination (rs 0.61, p<0.001).	8656906
Inflammation	Altered Intercellular Communication	The results brought the authors to a conclusion that Kislovodsk narzan is a caries-static agent which, if indicated, may be effectively used for the treatment of periodontal inflammations.	8658571
Inflammation, Intestinal Obstruction	Altered Intercellular Communication	One of the most common complications is bowel obstruction which can be caused by the angulation of the bowel or by inflammation, or by formation of granulation tissue (32.3%).	8659241
Fibrous, Granulomatous inflammation, Uveitis	Altered Intercellular Communication	Histopathologic examination of four eyes from these patients disclosed widespread destruction of the outer retina and retinal pigment epithelium, massive areas of subretinal fibrous tissue proliferation, granulomatous inflammation centered around degenerated and fragmented Bruch's membrane, and chronic uveitis.	8659601
Inflammation, Vasculitis, CTCAE, Necrosis	Altered Intercellular Communication	Adjacent vessels showed inflammation and fibrinoid necrosis of their walls suggestive of a vasculitis.	8666695
Inflammation, Fibrous, Rupture, Plaque, Atherosclerotic	Altered Intercellular Communication	The process of inflammation, involving foam-cell infiltration of the fibrous cap, may contribute to rupture of the atherosclerotic plaque.	8667496
Inflammation, Atrophy of kidney	Altered Intercellular Communication	On follow-up computed tomographic scans, the retroperitoneal inflammatory process resolved completely in 53% of the patients, but 47% of patients had persistent inflammation that involved the ureters in 32% and resulted in long-term solitary or bilateral renal atrophy in 47%.	8667508
Inflammatory, Inflammation	Altered Intercellular Communication	The study also documents that persistent retroperitoneal inflammation may be more prevalent than has been previously reported, and stresses the need for an improved understanding of the pathogenesis and long-term management of inflammatory AAAs.	8667508
Inflammation, Calcinosis, Edema	Altered Intercellular Communication	The cysties cause inflammation, oedema and residual calcification.	8668597
Inflammation, Arthritis	Altered Intercellular Communication	99Tcm-labelled polyclonal human immunoglobulin 99Tcm-HIG scintigraphy has been suggested as a technique to detect joint inflammation in arthritic disorders.	8668959
Granulomatosis with polyangiitis, Necrotizing vasculitis	Altered Intercellular Communication	The classic histologic features of Wegener's granulomatosis (WG) in lung include necrotizing granulomatous inflammation and necrotizing vasculitis.	8669527
Fibrosis Assessment, Diffuse alveolar hemorrhage, Capillaritis, Bronchitis	Altered Intercellular Communication	Recently, several histologic variants have been recognized, including cases characterized by bronchocentric inflammation, a marked eosinophil infiltrate, alveolar hemorrhage, and capillaritis or interstitial fibrosis.	8669527
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Other frequent findings included darkly staining multinucleated giant cells, prominent acute inflammation, aggregates of epithelioid histiocytes, hemosiderin-filled macrophages, and areas of nonspecific parenchymal fibrosis.	8669527
vascular inflammations	Altered Intercellular Communication	There are immunologic similarities with the vascular inflammation observed in GCA.	8670331
Inflammation, Synovitis	Altered Intercellular Communication	YKL-40 levels in serum and synovial fluid of patients with acute severe synovial inflammation were significantly higher (P < 0.05-P < 0.001) than those in patients with no, light or moderate synovitis of the knee joint.	8670576
Inflammation	Altered Intercellular Communication	Our data indicate that YKL-40 in synovial fluid and serum may reflect human articular cartilage degradation and the degree of synovial inflammation in the knee joint.	8670576
Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Inflammation of small-sized blood vessels is a hallmark of systemic lupus erythematosus (SLE).	8670594
Inflammation	Altered Intercellular Communication	There were significant correlations between both changes in D/P(creat) and UF with the cumulative dialysate leukocyte count, regardless of infecting organism, suggesting that intensity of peritoneal inflammation is also important.	8671821
Inflammation, Infection, Peritonitis	Altered Intercellular Communication	This process is exacerbated and accelerated by peritonitis, and appears to be proportional to the degree of associated inflammation and number of infections in close proximity.	8671821
Inflammation, Glomerulonephritis	Altered Intercellular Communication	Complement C4 is a component of the classical complement pathway, which is a major mediator of inflammation in many forms of glomerulonephritis.	8671963
ACSM3 gene, Inflammation	Altered Intercellular Communication	The cellular inflammation had been modulated within the CNS indicating a pathogenic role in the biochemical cascades following SAH.	8672265
Portal inflammation, Necrosis	Altered Intercellular Communication	In CR-SR cases, significant improvements (P < 0.01) occurred in periportal necrosis, intralobular necrosis, portal inflammation and total score.	8672762
Inflammation	Altered Intercellular Communication	Adhesion molecules are important signal transmitters of the immune system and may mediate the homing of leukocytes to sites of inflammation.	8674240
Inflammatory Bowel Diseases, Ischemia, Ulcerative Colitis, Irritable Bowel Syndrome, Communicable Diseases, Gastrointestinal inflammation, Crohn Disease	Altered Intercellular Communication	To investigate the specificities of these antibodies mucosal immunoglobulins were isolated from washings taken at endoscopy from 21 control patients with irritable bowel syndrome, 10 control patients with intestinal inflammation due to infection or ischaemia, and 51 patients with IBD: 24 Crohn's disease (CD, 15 active, nine quiescent), 27 ulcerative colitis (UC, 20 active, seven inactive).	8675088
Irritable Bowel Syndrome	Altered Intercellular Communication	Total mucosal IgG was much higher (p < 0.001) in active UC (median 512 micrograms/ml) and active CD (256 micrograms/ml) than in irritable bowel syndrome controls (1.43 micrograms/ml), but not significantly different from controls with non-IBD intestinal inflammation (224 micrograms/ml).	8675088
Ichthyosis Bullosa of Siemens, Ulcerative Colitis	Altered Intercellular Communication	Mucosal IgG bound to proteins of a range of non-pathogenic commensal faecal bacteria in active CD; this was higher than in UC (p < 0.01); and both were significantly greater than controls with non-IBD intestinal inflammation (CD p < 0.001, UC p < 0.01) or IBS (p < 0.001 CD and UC).	8675088
Inflammation, Gastritis, Crohn Disease	Altered Intercellular Communication	The characteristic appearance of H pylori negative gastritis was focal and mostly mild inflammation resembling the inflammatory changes seen in the gut in Crohn's disease.	8675090
Inflammation, Henoch-Schoenlein Purpura, Systemic Vasculitis	Altered Intercellular Communication	To study the expression of cell adhesion molecules in the renal biopsy specimens of patients with systemic vasculitis and Henoch-Schonlein purpura (HSP); to correlate this with the severity of glomerular inflammation.	8675737
Inflammation, Meningitis, Bacterial, Cerebrovascular Circulation	Altered Intercellular Communication	The increases of key mediators of inflammation and immunoactivation and of leucocyte count in the CSF of patients with high cerebral blood flow velocities suggest a role of excessive compartmentalised host defence in pathogenesis of disorders of cerebral blood flow in bacterial meningitis.	8676162
Chylopericardium, Myocarditis	Altered Intercellular Communication	Suppression of fluid accumulation following pericardial inflammation in a patient with primary chylopericardium.	8676555
Inflammation, Pericardial Effusion, CTCAE	Altered Intercellular Communication	The inflammation was easily treated with antibiotics, and the pericardial effusion no longer accumulated during a follow-up period of 10 months.	8676555
Cystitis	Altered Intercellular Communication	Micronucleus frequencies in urothelial cells of catheterized patients with chronic bladder inflammation.	8676918
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Epidemiological studies suggest an association between chronic inflammation and increased risk for cancer, although the mechanism underlying this relationship is unresolved.	8676918
Malignant neoplasm of urinary bladder, Cystitis	Altered Intercellular Communication	These individuals have chronic bladder inflammation and, as a population, an increased risk for bladder cancer.	8676918
Inflammation, Chromosomes	Altered Intercellular Communication	These data imply that chromosomal damage does not always occur during chronic inflammation.	8676918
Adenoma, Pituitary Apoplexy	Altered Intercellular Communication	In the absence of hormonal secretion or pituitary apoplexy, symptom-free giant adenomas of the pituitary are compatible with a long life.	8677484
Vascular anomaly, Diverticulosis	Altered Intercellular Communication	Abnormal endoscopic findings included diverticulosis, vascular malformations, cecal ulcer/inflammation, mass, and polyps.	8677933
Inflammation, Perforation (observation)	Altered Intercellular Communication	Perforation was directly attributable to an ancillary procedure (three routine biopsies, one electrocautery) in the cecal area in four patients, and cecal pathology (inflammation, ulceration) was a contributing risk factor in three patients.	8677933
Typhlitis	Altered Intercellular Communication	Ancillary endoscopic interventions in the cecal region should be minimized in elderly patients with evidence of cecal inflammation.	8677933
Gastric Ulcer, CTCAE 5, Acute and chronic inflammation	Altered Intercellular Communication	Endoscopy showed a giant gastric ulcer, and biopsies revealed only chronic active ulcerative inflammation.	8677958
Fibrosis, Liver, Hepatic inflammation	Altered Intercellular Communication	However, the degree of portal iron deposits did correlate with hepatic inflammation activity (tau = 0.55, p < 0.001) and the severity of liver fibrosis (tau = 0.60, p < 0.001), and it correlated negatively to the response to interferon (tau = -0.49, p < 0.001).	8677997
Obstruction, Bronchitis	Altered Intercellular Communication	Reexpansion was progressive, gradual, and dependent on improved compliance, clearing of bronchial inflammation and obstruction, and pleural cleansing.	8678646
Inflammatory Bowel Diseases, Inflammation, Pouchitis	Altered Intercellular Communication	The present study suggests that increased levels of soluble ICAM-1 and soluble E-Selectin occur during active inflammatory bowel disease and pouchitis, which may be used as sensitive markers of continuing inflammation.	8680902
Inflammation, Dental caries	Altered Intercellular Communication	The incidence was not influenced by inflammation around the tooth crown of the third molar, by tooth caries, or by metal fillings present in the third molar.	8680969
Abdominal actinomycosis, Specimen Type - Fistula, Arteritis	Altered Intercellular Communication	Abdominal actinomycosis presents itself as a rare chronic bacterial inflammation, usually located in the right lower abdomen, with local abscess or fistula formation as well as tumour-like infiltration of the surrounding tissues.	8684243
Inflammation, Etoposide/Methotrexate, Ischemia	Altered Intercellular Communication	Because APKD could account for only 11% of the patients with VMC, we suggest that VMC, in the absence of APKD, are a manifestation of a different disease, which could be genetic or secondary to inflammation or ischemia.	8685220
Inflammation, Contracture	Altered Intercellular Communication	These therapeutic complexes proved to be analgetic, effective against local inflammation in the joints, to relax muscular tension and pain contractures, to enhance functional activity of the affected joints.	8686217
Inflammation, Hyperparathyroidism, Osteoporosis, Postmenopausal, Refractory anemias, Osteopenia	Altered Intercellular Communication	From these findings, we suggest that the bone loss in RA patients is affected by severity of inflammation, disuse, postmenopausal osteoporosis and secondary hyperparathyroidism.	8686466
Craniocerebral Trauma, Comatose	Altered Intercellular Communication	CSF neurotransmitter metabolites in comatose head injury patients during changes in their clinical state.	8686526
Craniocerebral Trauma	Altered Intercellular Communication	The results show that the increased turnover of CNS neurotransmitters in severe head injury normalizes during recovery.	8686526
Inflammation	Altered Intercellular Communication	Pathological findings revealed chronic inflammation, and malignant cells were not found in the resected specimens.	8686585
Pneumothorax, Pleurisy, Lymphoma, Pleural Tuberculosis, Lymphoma, Non-Hodgkin	Altered Intercellular Communication	Pyothorax-associated lymphomas (PALS) are non-Hodgkin's lymphomas that arise in the pleural cavity after long-standing pleural inflammation resulting from therapeutic artificial pneumothorax or from tuberculosis pleuritis.	8686762
Inflammation, Myxoma, Necrosis	Altered Intercellular Communication	The locus of enhancement on post-Gd-DTPA images fitted with histologic myxoma or inflammation, and the unenhanced region reflected the necrosis or cystic changes in the specimens, respectively.	8686964
Inflammation, Communicable Diseases, White matter degeneration, Human T-lymphotropic virus 1, Leukemia, T-Cell	Altered Intercellular Communication	Infection by human T-lymphotropic virus type I (HTLV-I) is associated with adult T-cell leukemia and a slowly progressive disease of the central nervous system (CNS), HTLV-I-associated myelopathy/tropical spastic paraparesis, characterized pathologically by inflammation and white matter degeneration in the spinal cord.	8687197
Inflammation, White matter	Altered Intercellular Communication	After using double-label in situ hybridization techniques, we now report definitive localization of HTLV-I tax gene expression in CD4+ T lymphocytes in areas of inflammation and white matter destruction.	8687197
Multiple Organ Failure, Inflammation, Sepsis, Traumatic injury	Altered Intercellular Communication	We conclude that sE-cadherin is increased in inflammation and injury, and may be related to the degree of multiorgan failure after sepsis.	8688260
Inflammation, polychondritis, Systemic disease	Altered Intercellular Communication	Relapsing polychondritis is an episodic systemic disorder, characterized by recurrent inflammation that affects cartilaginous structures, the cardiovascular system, eyes and ears.	8688477
Renal Insufficiency, Rheumatoid Arthritis, Inflammation, Arthropathy	Altered Intercellular Communication	Many rheumatoid arthritis patients have renal dysfunction induced either by the drugs used to treat their joint disease or by the chronic inflammation.	8689286
Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Our aim was to characterize the effect of H. pylori infection and gastric mucosal inflammation on the peripheral blood leukocyte count.	8689908
Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The results show that mucosal inflammation due to H. pylori infection is reflected in the amount of peripheral blood leukocytes.	8689908
Inflammation, Sinusitis, Allergic	Altered Intercellular Communication	These results suggest that the pathogenesis or the inflammatory process of sinusitis is heterogeneous and whether the inflammation is allergic or not may be important.	8691305
Necrotizing granulomatous inflammation, Arteritis, Necrotizing fasciitis	Altered Intercellular Communication	Arteritis of peribronchial muscular arteries with medial destruction was seen in lung biopsy specimens, and periglomerular granulomatous inflammation and necrotizing glomerulitis were seen in renal biopsy specimens.	8691664
Inflammation	Altered Intercellular Communication	Finally, the aberrant artery and the pulmonary artery communicated due to chronic inflammation in the sequestrum.	8691666
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Those lesions had large numbers of cancer cells in the ducts and also showed periductal inflammation.	8692661
Inflammation	Altered Intercellular Communication	These results lead to the conclusion that HLA-DR antigen expression does not precede, but is associated with the inflammation.	8693495
Inflammation, Pneumonia, Bronchiolitis Obliterans Organizing Pneumonia, Fibrosis Assessment, Bronchiolitis Obliterans	Altered Intercellular Communication	Idiopathic bronchiolitis obliterans organizing pneumonia (BOOP) is characterized by air space inflammation and fibrosis of unknown origin.	8697838
Hepatic inflammation	Altered Intercellular Communication	HBV mutants with core gene deletions (37-250 base pairs) were detected in patients with long-standing HBV replication and ongoing hepatic inflammation, always together with the wild-type strain.	8698197
Inflammation, Crohn Disease	Altered Intercellular Communication	Knowledge of the presence and the degree of inflammation in Crohn's disease would be useful in multicentre therapeutic trials.	8698564
Arthritis, Chronic pain	Altered Intercellular Communication	Tolerance may be less pronounced for peripherally than for centrally acting opioids, which provides a promising perspective for the treatment of chronic pain in arthritis and other inflammatory conditions.	8698872
Inflammation	Altered Intercellular Communication	PMN activation markers, cytokine release, and other inflammation proteins were significantly increased compared with normal subjects.	8699873
Inflammation, Infiltration, Exudative	Altered Intercellular Communication	In the gastric body, there were prevalent chronic inflammatory processes with developed mononuclear infiltration in reproductive females whereas there were predominant elements of exudative and destructive inflammation in older females.	8700592
Inflammation, Peptic Ulcer, Ulcer	Altered Intercellular Communication	In 16/26 (61%), alterations were observed in endoscopy (gastric inflammation in eleven, peptic ulcer in two and ulcer scars in three cases).	8701044
Inflammation, Peptic Ulcer	Altered Intercellular Communication	Of the patients with endoscopic gastric inflammation, presented positive as well as all (100%) bearers of scar or peptic ulcer.	8701044
Gastric Infection, Gastritis, Ulcer	Altered Intercellular Communication	Our conclusion is that the prevalence of gastric infection for H. pylori in symptomatic patients is high, correlated with chronic gastric inflammation and ulcers.	8701044
Inflammation	Altered Intercellular Communication	[Virus titre and histological inflammation activity in chronic hepatitis C].	8701257
Inflammation, Viremia, Hepatitis C	Altered Intercellular Communication	We conclude that in patients with a chronic hepatitis C marked viremia points to a histologically active inflammation.	8701257
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Histopathological examination revealed nonperforated and perforated appendicitis in 63.3% and 13.1%, respectively, and no inflammation in 10.8%.	8703146
Conjunctivitis	Altered Intercellular Communication	Of patients with more than 24 months follow up, progression of cicatrisation occurred in 35% of eyes (16/46) all but one of which were associated with episodes of conjunctival inflammation.	8703876
Inflammation, Epithelial, Keratopathy, Conjunctivitis, Visual	Altered Intercellular Communication	Persistent epithelial defects, limbal inflammation, and ongoing conjunctival inflammation are important factors that lead to keratopathy and visual handicap.	8703876
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	There was extensive mucosal inflammation throughout colon and rectum resembling ulcerative colitis.	8707099
Neurogenic Inflammation	Altered Intercellular Communication	Assessment of axon reflex vasodilatation was simultaneously employed to test for neurogenic inflammation.	8707925
Inflammatory dermatosis	Altered Intercellular Communication	We conclude that damage of lower motor neuron leads to ipsilateral down-regulation of T cell-mediated cutaneous inflammation.	8707925
Inflammation, Duodenitis, Intestinal metaplasia, Atrophic, Chronic gastritis	Altered Intercellular Communication	There were no differences in the density of H pylori infection, inflammation, atrophy, or intestinal metaplasia between patients with chronic gastritis only and those with duodenitis.	8707950
Duodenitis, Gastritis, Duodenal inflammation	Altered Intercellular Communication	These results suggest that H pylori positive patients with duodenitis have a more severe form of gastritis than those without associated duodenal inflammation.	8707950
Inflammation, Dental Plaque	Altered Intercellular Communication	Previous investigations have reported increased plaque formation in the presence of gingival inflammation as compared with gingival health.	8707973
Acute Lung Injury, Pneumonitis	Altered Intercellular Communication	Relationship between pulmonary oxygen consumption, lung inflammation, and calculated venous admixture in patients with acute lung injury.	8708163
Pneumonitis	Altered Intercellular Communication	However, there was no correlation between VO2pulm and the intensity of pulmonary inflammation.	8708163
Down Syndrome, "Alzheimers Disease", Illness (finding)	Altered Intercellular Communication	Our results support the idea that besides other neurotransmitter systems, endogenous polyamine levels are altered in dementing illnesses such as Alzheimer disease and Down syndrome.	8710184
Inflammation	Altered Intercellular Communication	Her history was uneventful apart from an acute inflammation of the subcutaneous tissue in the right leg 20 years earlier.	8711814
Communicable Diseases, Inflammation	Altered Intercellular Communication	Clinical and microbiological findings led the authors to the conclusion that antibacterial drugs rovamycin and amox-clav are active against ENT infection and inflammation.	8711846
Inflammation	Altered Intercellular Communication	There were no clinical signs of inflammation and laboratory and technical finding were completely normal.	8711943
Inflammation, Hyperplasia, Squamous metaplasia	Altered Intercellular Communication	In addition to mucus accumulation, these pseudoneoplasms feature hyperplasia and squamous metaplasia of the ductal lining epithelium, with varying degrees of inflammation.	8712179
Inflammation, Biliary calculi	Altered Intercellular Communication	The removed gallbladder has been histologically examined, observing the absence of gallstone and the presence of chronic inflammation of the gallbladder wall.	8712602
Inflammation	Altered Intercellular Communication	In airway reconstruction, wound contraction secondary to chronic inflammation is a liability.	8712633
Refractory anemias, Inflammation	Altered Intercellular Communication	RA patients were classified as having severe (n = 82) or mild disease (n = 89) according to clinical joint evaluation, radiological score, biological inflammation, and the presence of HLA-DR1 or -DR4 alleles.	8712873
Wallerian Degeneration, Inflammation, Demyelination, Remyelination	Altered Intercellular Communication	Sural nerve biopsy in 3 patients showed evidence of demyelination, remyelination, Wallerian degeneration and myelin breakdown but none had features of inflammation.	8713263
Gastrointestinal Hemorrhage, Colorectal Neoplasms, Inflammation, Feces	Altered Intercellular Communication	Faecal specimens and smears were collected from healthy subjects (n = 22) and from patients with gastrointestinal bleeding (n = 12) or inflammation (n = 22), colorectal neoplasia (n = 15), or miscellaneous diseases with a low risk of excessive faecal protein loss (n = 30).	8713696
Inflammation, Lymphangiectasis	Altered Intercellular Communication	Conjunctival biopsies showed chronic tissue inflammation or lymphangiectasia.	8713933
Inflammatory disease of mucous membrane, Ulcer	Altered Intercellular Communication	The frequency of ulcer lesions was 13.7% while non-ulcer, mucosal inflammation was diagnosed with a frequency of 33.7%.	8714235
Inflammation, Asthma	Altered Intercellular Communication	Levels of eosinophil cationic protein (ECP) in serum are abnormally high in bronchial asthma, and may reflect the degree of eosinophilic inflammation in the lung.	8717287
Conjunctivitis	Altered Intercellular Communication	The majority of patients had minimal conjunctival inflammation, an anterior stromal cellular reaction and minimal anterior chamber activity.	8719670
Inflammation	Altered Intercellular Communication	This study showed that mononuclear cells infiltrating along the margins of extruded discs expressed inflammatory mediators and might induce neovascularization and persistence of inflammation.	8720410
Retinal Degeneration	Altered Intercellular Communication	Progressive retinal degeneration also leads to alterations in retinal neurotransmitters.	8720675
Inflammation	Altered Intercellular Communication	cTNF-R1 binds TNF-alpha and is important in regulating TNF-alpha-mediated inflammation.	8721479
Gastroesophageal reflux disease, Communicable Diseases, Vocal Cord Dysfunction, Traumatic injury	Altered Intercellular Communication	The many etiologic factors (laryngeal intubation, gastro-esophageal refluxes, blunt trauma of the larynx, vocal dysfunction), sometimes concomitant and with the possible addition of enhancing circumstances (upper aerodigestive tract inflammation, naso-gastric tube, smoking and alcohol abuse), converge to a single pathogenetic mechanism: an ulceration of the mucosa and the pericondrium, sometimes complicated by an infection, which does not heal but instead produces a typical granulation tissue with capillaries oriented radially from the center of the lesion.	8721728
Granulomatous inflammation	Altered Intercellular Communication	Coxiella burnetii is a well-known causative agent of granulomatous inflammation and an inducer of morphological changes and transformation of human B lymphocytes in vitro.	8722296
Necrotizing granulomatous inflammation, Reticulosis	Altered Intercellular Communication	An association of the organism with polymorphic reticulosis (PMR), a malignant granulomatous inflammation characterized by polymorphic lymphocytes, was examined.	8722296
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	The analysis of ANCA+ and ANCA- patients revealed that the pANCA+ group exhibited significantly higher serological markers of inflammation (p < 0.005) and a higher incidence of rheumatoid factor (p < 0.005).	8724292
Inflammation	Altered Intercellular Communication	On pathological examination mild chronic inflammation was reported in 19 cases and minimal changes in 8.	8725452
Inflammation, Hydrops	Altered Intercellular Communication	The obstruction of the cystic duct was due to chronic inflammation and had resulted in hydrops of the gallbladder.	8726844
Inflammation, Diverticulum	Altered Intercellular Communication	Histopathologic examination of the dural diverticulum revealed a residual change after old inflammation.	8727460
Encrusted cystitis	Altered Intercellular Communication	Alkaline encrusted cystitis is a rare inflammatory condition of the bladder which has been reported sporadically over the past 80 years.	8729045
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Incubation of mucosa from areas of active inflammation in ulcerative colitis with the calcium ionophore A23187 increased the levels of C16:0 PAF by 2-3 fold and also increased the levels of C16:0 lyso-PAF.	8729129
Inflammation, Neoplasms, MYELOPROLIFERATIVE SYNDROME, TRANSIENT, Blood Coagulation Disorders, Hematological Disease, Liver Cirrhosis	Altered Intercellular Communication	Other causes may be cirrhosis, tumors and inflammation of the abdomen, coagulation disorders and hematologic diseases including latent myeloproliferative syndrome.	8729327
polyps, Nasal obstruction present finding, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Authors report two cases of 31 and 42 year old women who for many years had a unilateral nasal obstruction: first case due to a large polyp, second one due to a mucosal inflammation but both caused by a rhinolithiasis.	8729405
Inflammation, Dysplasia, Carcinoma, Squamous cell carcinoma, Lichen Planus, Hyperplasia	Altered Intercellular Communication	The pathological lesions consisted of chronic inflammation (n = 10), lichen planus (n = 7), fibrous hyperplasia (n = 11), dysplasia (n = 5), squamous cell carcinoma (n = 22) and epithelium adjacent to carcinoma (n = 6).	8729615
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumour necrosis factor (TNF) and interleukin-1 (IL-1) are powerful mediators with a key role in inflammation.	8730328
Inflammation	Altered Intercellular Communication	This study was undertaken to study the presence of TNF and IL-1 in tuberculous effusion where there is marked inflammation and where examination of the pleural fluid may give information about the local inflammatory reaction.	8730328
Inflammation	Altered Intercellular Communication	Adhesion molecules play a critical role in regulating leucocyte migration at sites of inflammation.	8731563
Inflammation, Demyelination	Altered Intercellular Communication	A general pattern emerged, with CD34 antigen reactivity predominantly negative in areas of inflammation with demyelination but positive in adjacent non-inflamed tissue, irrespective of myelin pathology.	8732185
Inflammation, Demyelinating Diseases	Altered Intercellular Communication	We conclude that perivascular inflammation is a key factor in the absence of immunoreactivity of CD34 in the CNS in demyelinating disease.	8732185
Inflammation, Ischemia	Altered Intercellular Communication	(p < 0.05, respectively) These results support the hypotheses that low-grade inflammation is associated with vascular risk factors and that inflammatory mechanisms may contribute to the risk of organ ischemia.	8732628
Degenerative polyarthritis, Inflammation, Refractory anemias	Altered Intercellular Communication	Clinical assessment of inflammation (graded 0-6) was undertaken in OA and RA patients.	8733439
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	Chronic inflammation in inflammatory bowel disease (IBD; Crohn's disease and ulcerative colitis) may be attributed partly to increased secretion of inflammatory cytokines.	8734357
Carpal Tunnel Syndrome, Inflammation, Musculoskeletal Pain	Altered Intercellular Communication	This form of presentation and its response to treatment suggest that the symptoms of carpal tunnel syndrome are caused by the inflammation of the carpal synovial, which is an unfrequent manifestation of polymyalgia rheumatica.	8734933
Amyotrophic Lateral Sclerosis, Inflammation, Prion Diseases, Neuronal degeneration	Altered Intercellular Communication	Amyotrophic lateral sclerosis (ALS) resembles the spongiform encephalopathies in its dual pattern of inherited and sporadic cases, its uniform prevalence in different populations, its late onset (suggestive of a long incubation period) and its pathological picture of neuronal degeneration without inflammation.	8737921
senile, Data types - Address	Altered Intercellular Communication	Increased Cx43 expression in AD may represent an attempt to maintain tissue homeostasis by augmented intercellular communication via gap junction formation between astrocytic processes that invest senile plaques, or alternatively, an aberrant induction of astrocytic Cx43 expression which may further compromise homeostasis and exacerbate pathological conditions in the microenvironment of amyloid plaques.	8738268
Inflammation, Giant Cell Arteritis	Altered Intercellular Communication	The mean daily prednisone dose at the time of sampling was significantly lower in giant cell arteritis patients with anti-cardiolipin antibodies (p < 0.05); this difference may account for the apparent correlation between anti-cardiolipin antibodies and laboratory markers for inflammation.	8738442
Inflammation	Altered Intercellular Communication	Perianeurysmal inflammation may contribute to the development of destructive vertebral and discal lesions.	8738450
Epithelial Damage, Asthma, Bronchial Hyperreactivity, Eosinophilic inflammation	Altered Intercellular Communication	Airway eosinophilic inflammation, epithelial damage, and bronchial hyperresponsiveness in patients with mild-moderate, stable asthma.	8738515
Inflammation, Asthma	Altered Intercellular Communication	Variability of airway structure and inflammation in normal subjects and in cases of nonfatal and fatal asthma.	8739471
Airway structure, Asthma	Altered Intercellular Communication	The quantitative assessment of airway inflammation in patients with apparently similar clinical severity of asthma has yielded variable results.	8739471
Inflammation	Altered Intercellular Communication	Youth, pigmented race and anterior segment inflammation have been shown to be associated with trabeculectomy failure.	8739683
Orbital Pseudotumor	Altered Intercellular Communication	The purpose of this study was to review our clinical experience with 132 idiopathic orbital inflammation cases seen between 1971 and 1994.	8739689
HTLV-I Infections, Inflammation, Ulcerative Colitis, Uveitis	Altered Intercellular Communication	Together with uveitis and ulcerative colitis in his past history, the persistent respiratory symptoms of this patient can be attributed to non-neoplastic inflammation due to the chronic HTLV-I infection.	8739787
allergic inflammation	Altered Intercellular Communication	Does laser turbinectomy influence local allergic inflammation in the nose?	8739871
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Within the group grafted with protected islets, the incidence of diabetes was reduced (37 vs 75%; p < 0.01), the onset of disease was delayed (p < 0.02), and the severity of lymphocytic inflammation of endogenous islets was reduced (p < 0.02).	8739911
Inflammation, Councilman body	Altered Intercellular Communication	Five histological aspects were scored: periportal inflammation, lobular inflammation, ballooning, Councilman bodies and lymphocyte follicles.	8740843
Inflammation, Hepatitis B	Altered Intercellular Communication	For the hepatitis B cohort a statistical significant correlation was found between alanine aminotransferase and periportal inflammation (p = 0.0001), lobular inflammation (p = 0.0002) and Councilman bodies/area (p = 0.003).	8740843
Inflammation, Hepatitis C	Altered Intercellular Communication	In the hepatitis C study population alanine aminotransferase correlates with both periportal inflammation (p = 0.007) and lymphocyte follicles/Area (p = 0.02).	8740843
Intraocular inflammation, Traumatic injury, Endophthalmitis	Altered Intercellular Communication	Nevertheless, sympathetic ophthalmia should be taken into consideration if there is a bilateral intraocular inflammation, even without trauma, as in two of our cases (cases 1 and 2).	8741154
Inflammation, Blood Coagulation Disorders	Altered Intercellular Communication	The patient had a decreased serum level of alpha l-antitrypsin, which may have been associated with the development of uncontrolled inflammation and coagulation disorder.	8741321
Inflammation, Rheumatic disease of heart valve, Bacterial Endocarditis	Altered Intercellular Communication	All cases of active infective endocarditis accompanied with rheumatic valvular disease underwent surgery after a suppression of active inflammation by medical treatment.	8741431
Inflammation, Behcet Syndrome	Altered Intercellular Communication	51 on HLA-B locus and thus we suspected that valve detachment might have been due to inflammation of the aortic wall caused by a subtype of Behcet disease.	8741446
Communicable Diseases, Inflammation	Altered Intercellular Communication	Additional factors that can improve the specificity of the bone scan are discussed, as are the panoply of more recent scintigraphic approaches aimed at distinguishing infection from aseptic inflammation in the extremity.	8741887
Alzheimers Disease	Altered Intercellular Communication	Monoaminergic neurotransmitters, their precursors and metabolites in brains of Alzheimer patients.	8742039
Inflammation, Asthma, Bronchial Hyperreactivity	Altered Intercellular Communication	As shown by investigations of external respiration and bronchoalveolar lavage with estimation of cytogram, metacholine provocative tests, fiber bronchoscopy, budesonide inhalations relieved clinical symptoms of asthma, bronchial hyperreactivity and inflammation.	8744104
Inflammation, Hepatobiliary Disorder, Fibrosis Assessment, fibrogenesis	Altered Intercellular Communication	We measured serum concentrations of the N-terminal peptide of type III procollagen (PIIIP) and laminin (Lam-P1) in patients with chronic viral liver disease in the various stages of the clinical course, to judge their value in assessing liver fibrogenesis, and also compared them with a number of liver function tests and histological scores of inflammation and fibrosis.	8745719
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Serum PIIIP and Lamp-P1 were determined by radioimmunoassay; hepatic function was measured by routine assay; liver fibrosis and inflammation were graded on a 0-3 score scale.	8745719
Inflammation, atherosclerotic	Altered Intercellular Communication	The presence of such inflammation and subsequent organ adherence makes surgical repair of IAAs more challenging than repair of simple atherosclerotic aneurysms.	8746829
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	It is concluded that IAA represents a spectrum of retroperitoneal fibrosis and inflammation that is best treated surgically via a retroperitoneal approach.	8746829
Ischemia	Altered Intercellular Communication	The excitatory amino acid neurotransmitters glutamate and aspartate have been shown to be of particular importance for ischemia and ischemic neuronal damage.	8747946
Aneurysm, Inflammation	Altered Intercellular Communication	At surgery, the aneurysm was found to be surrounded by thickened leptomeninges, which histologically presented dense inflammation and remains of Cysticercus.	8747971
Inflammation, Squamous cell carcinoma, Dysplasia	Altered Intercellular Communication	They were also identified in samples of squamous carcinoma, severe dysplasia and chronic inflammation.	8749207
Inflammation	Altered Intercellular Communication	Gadolinium-DTPA enhancement may visualize lesions that suggest an inflammation associated with blood-brain-barrier alteration and indicate the diagnosis before serological results are available.	8750559
Abscess, Inflammation of perianal region	Altered Intercellular Communication	The short inversion time inversion recovery sequence, which was unable to distinguish small abscesses from perianal inflammation and showed spurious high signal in old fibrotic tracks, led our observers to misdiagnose five cases.	8751692
Inflammation, Labial adhesions	Altered Intercellular Communication	Etiological factor in labial adhesions are thought to include a combination of local inflammation and estrogen deficiency.	8752547
Inflammation, Asthma, Bronchitis	Altered Intercellular Communication	IL-8 is involved in neutrophilic inflammation in asthma and chronic bronchitis, but differences in the IL-8 regulation of neutrophils were observed in both diseases.	8753849
Inflammation	Altered Intercellular Communication	Histological evidence on the removed tissue specimens from 6 patients elucidated a number of features characteristic for active specific inflammation in adults versus children.	8754881
Alveolus, Inflammation, Idiopathic Pulmonary Fibrosis, Alveolitis	Altered Intercellular Communication	Although the etiology of idiopathic pulmonary fibrosis (IPF) is still uncertain, it is postulated that IPF begins with an initial inflammatory lesion localized to the alveolus and progresses on to chronic inflammation with alveolitis.	8756825
Pneumonitis	Altered Intercellular Communication	Immunoelectron microscopic findings support the idea that Tn in UIP is synthesized by the regenerating epithelial rather than interstitial cells in response to pulmonary interstitial inflammation.	8756830
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Different stages of inflammation could be found simultaneously, reflecting the relapsing nature of vasculitis.	8757068
Inflammation, Asthma	Altered Intercellular Communication	Involvement of endothelin in mononuclear phagocyte inflammation in asthma.	8757219
Airway structure, Asthma	Altered Intercellular Communication	This study suggests a role for endothelin in airway inflammation in asthma.	8757219
Thyrotoxicosis	Altered Intercellular Communication	To identify the clinical, demographic, and hormonal features that characterize and place patients at greater risk for complicated thyrotoxicosis.	8757360
Tumor necrosis, Inflammation, Neoplasms	Altered Intercellular Communication	Furthermore, there was no correlation with the serum level of C-reactive protein, fibrinogen or tumour necrosis factor alpha suggesting that the elevation of E-selectin is independent of inflammation in tumour patients.	8758256
Inflammation	Altered Intercellular Communication	Women with gynecologic inflammation had more cases with vaginal GBS colonization.	8758413
Conjunctivitis	Altered Intercellular Communication	Twenty consecutive patients with moderate or marked conjunctival inflammation due to OCP were treated with oral sulphapyridine 500 mg twice daily.	8759268
Inflammatory abnormality of the eye	Altered Intercellular Communication	The degree of ocular inflammation was assessed as nil, mild, moderate, marked, or severe.	8759268
Lymphoma, Malt Grain	Altered Intercellular Communication	Several chronic inflammatory conditions and genetic alterations are likely to be involved in the pathogenesis of low-grade lymphoma of MALT type.	8759899
Granulomatous inflammation, Acquired Immunodeficiency Syndrome, Granuloma	Altered Intercellular Communication	None of the acquired immunodeficiency syndrome (AIDS) patients had granulomatous inflammation, whereas most non-HIV-associated cases had granulomas, supporting a role for cell-mediated immunity in CME.	8760020
Inflammation, Asthma	Altered Intercellular Communication	[Bronchial asthma with inflammation of the nose mucous membrane induced by occupational exposure to methyl methacrylate in a dental technician ].	8760510
Refractory anemias, Inflammation, Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	To examine the involvement of COX-2 in inflammation, we analysed the expression of this gene in human rheumatoid arthritis (RA) and in rat adjuvant-induced arthritis.	8761181
Inflammation, Tonsillitis	Altered Intercellular Communication	In children what is considered to be chronic tonsillitis may perhaps be more correctly regarded as an expression of recurrent inflammation.	8762597
Inflammation, Fibrosis Assessment, Fatty degeneration, Necrosis	Altered Intercellular Communication	On log linear analysis, piecemeal necrosis, lobular inflammation and steatosis were linked directly with fibrosis.	8763259
Inflammation, Portal tract inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Portal tract inflammation was linked directly and indirectly via piecemeal necrosis and lobular inflammation with fibrosis.	8763259
Portal tract inflammation, Hepatitis C, Damage	Altered Intercellular Communication	Portal tract inflammation with lymphoid aggregates or follicles, together with fatty change, bile duct damage and/or lobular activity, are characteristic of chronic HCV infection, confirming previous reports.	8763259
Inflammation, Fibrosis Assessment, Fatty degeneration, Necrosis	Altered Intercellular Communication	Piecemeal necrosis, lobular inflammation, portal inflammation, and steatosis are linked directly with fibrosis in this statistical model, suggesting a close inter-relation in the development of fibrosis/cirrhosis.	8763259
Psoriatic Juvenile Idiopathic Arthritis, Inflammation	Altered Intercellular Communication	As the priming effects of PAF have been shown, for leucocytes and endothelial cells, to enhance their inflammatory response, we assume that PAF has roles in the acute phase of psoriatic and leucotactic inflammation.	8763425
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To provide insight into the migration and activation of T-cells at the site of inflammation in rheumatoid arthritis (RA), CD27 expression by T-cells in peripheral blood (PB), synovial fluid (SF), and synovial tissue (ST) as well as the levels of the soluble form of CD27 (sCD27) in plasma and SF were studied in patients with RA.	8764557
Inflammation	Altered Intercellular Communication	These activated T-cells are likely to play a role in synovial inflammation.	8764557
Communicable Diseases, Inflammation	Altered Intercellular Communication	These patients were followed prospectively for clinical signs of conjunctival breakdown, graft melt, tube erosion, graft-related inflammation, infection, and graft-related complications.	8764803
Intraocular inflammation	Altered Intercellular Communication	All eyes tolerated the fascia lata grafts well without clinical evidence of graft-related conjunctival, scleral, or intraocular inflammation.	8764803
Lymphadenopathy	Altered Intercellular Communication	Of these 7 patients with palpable inguinal adenopathy, three (42.8%) had an infective-inflammatory condition.	8766803
Pruritus Vulvae, Inflammation	Altered Intercellular Communication	Typical symptoms consisted of pruritus vulvae, local inflammation and a curdy vaginal discharge.	8767274
Hypergammaglobulinemia, Hepatitis, Insemination, Artificial, Homologous, Autoimmune Chronic Hepatitis, Hypertransaminasaemia	Altered Intercellular Communication	Autoimmune hepatitis (AIH), a liver inflammatory condition, is characterized by hypergammaglobulinemia, hypertransaminasemia, presence of autoantibody and periportal hepatitis revealed by histology.	8767573
Inflammation, Oral Medicine, Collagen Diseases	Altered Intercellular Communication	Oral amtolmetineguacyl 600 mg/day in a single blind comparative trial with placebo carried out in 24 patients suffering from rheumatic disorders of varying severity, reduced statistically all the symptomatology correlated to inflammation.	8767977
Inflammation	Altered Intercellular Communication	Mycotic inflammations of the anterior segment of the eye are relatively rare in our geographical zone.	8768474
Inflammation, atherosclerotic	Altered Intercellular Communication	Atherosclerotic plaques exhibit a series of features that are similar to those of chronic inflammation.	8770312
Seizures, Psychotic Disorders	Altered Intercellular Communication	The results are discussed in the context of the role of neurotransmitters such as glutamate, gamma-aminobutyric acid, adenosine, and dopamine on seizure vulnerability and psychosis.	8771616
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	These data suggest that transforming growth factor-beta may have an important role in liver fibrosis and inflammation.	8773910
Granulomatous inflammation	Altered Intercellular Communication	These were indicative of an extension of granulomatous inflammation of the cavernous sinus to the pituitary portal system and the gland itself.	8774971
Inflammation, Leucocytic infiltrate	Altered Intercellular Communication	In 34% of these cases the eradication was followed by a diminution of activity of gastric antral mucosa inflammation and in 20% of these children the resolution of the inflammatory infiltration in the gastric mucosa was seen.	8775326
Inflammation, Hyperpigmentation, Endocrine System Diseases	Altered Intercellular Communication	The skin lesions in these patients could be easily confused with hyperpigmentation caused by endocrine disorders, drugs, heavy metals, polychlorinated biphenyl or cutaneous inflammation.	8776378
Inflammation	Altered Intercellular Communication	Percutaneous needle biopsy with a Trucut needle revealed non-specific chronic inflammation.	8778475
Choroidal Detachment, Inflammation, Hyphema	Altered Intercellular Communication	Complications were iris incarceration/synechia (n = 33), hypotony (n = 36) with consequent choroidal detachment (n = 8), hyphema (n = 19) and more pronounced inflammation symptoms (n = 10).	8778490
Inflammation, Necrosis, Muscle (organ)	Altered Intercellular Communication	it is advisable to use ultraphonophoresis of vasoactive ointments venoruton and nitro-ointment in patients having capillary-trophic insufficiency, slow repair of the necrotic zone, postinfarction inflammation in muscular and connective tissue structures of the upper shoulder girdle.	8779192
Achalasia, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Three patients with vigorous achalasia had normal ganglion cell numbers (0.79-0.91 ganglion cells per high-power field) and at least mild myenteric inflammation without neural fibrosis.	8780569
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The remaining 8 patients had few or no ganglion cells (0-0.30 ganglion cells per high-power field) and at least mild myenteric inflammation and neural fibrosis.	8780569
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The earliest pathological changes consist of myenteric inflammation with injury to and subsequent loss of ganglion cells and injury to and fibrosis of myenteric nerves.	8780569
Inflammation, Atrophic	Altered Intercellular Communication	The autoantibody status correlated with the presence and degree of inflammation and atrophy of the glands.	8780570
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In HBeAg-negative stage, both inflammation and fibrosis were more pronounced in carriers infected with wild-type HBV compared with precore mutants.	8781313
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	C-1858 strains were associated with more inflammation and fibrosis compared with T-1858 strains.	8781313
Alzheimers Disease", senile	Altered Intercellular Communication	Inflammatory processes have been implicated in the formation of senile plaques in the cerebral cortex of patients with dementia of the Alzheimer type (DAT), since several inflammation-induced proteins are present within these plaques.	8781660
Inflammation, senile	Altered Intercellular Communication	This is in contrast to the putative primary involvement of inflammation in the formation of cerebrocortical classic and diffuse senile plaques.	8781660
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	We therefore have no evidence that PAF has an important role as a mediator in the inflammation of ulcerative colitis.	8781921
Crohns disease of large bowel", Acute and chronic inflammation, Crohn Disease	Altered Intercellular Communication	Chronic intestinal inflammation induced by 2,4,6,-trinitrobenzene sulfonic acid (TNBS) is characterized by a transmural granulomatous colitis that mimics some characteristics of human Crohn's disease.	8782457
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	The data provide direct evidence for the central importance of p65 in chronic intestinal inflammation and suggest a potential therapeutic utility of p65 antisense oligonucleotides as a novel molecular approach for the treatment of patients with Crohn's disease.	8782457
Calcific periarthritis	Altered Intercellular Communication	Basic calcium phosphate (BCP) crystal deposition around the joints may sometimes lead to an acute inflammatory condition called calcific periarthritis.	8783684
Inflammation, Perforation (observation)	Altered Intercellular Communication	The authors recommend appendectomy for patients with pointed foreign bodies in the appendix to avoid inflammation and perforation.	8786509
Inflammation, Angina Pectoris	Altered Intercellular Communication	The evidence of elevated levels of acute-phase proteins in unstable angina is in line with a growing body of evidence that suggests that inflammation plays a role in this syndrome and is an indirect sign of increased production of interleukin-6, which is the major determinant of acute-phase-protein production by the liver.	8790019
Inflammation, Ventricular aneurysm	Altered Intercellular Communication	Involvement of the left ventricle and/or ventricular septum, right ventricular aneurysms, and inflammation were found almost exclusively in the fibrofatty variety.	8790036
Cessation of life, Inflammation	Altered Intercellular Communication	Whether the inflammation is a primary event or a reaction to spontaneous cell death remains unclear.	8790036
Hypercalcemia, Hematologic Neoplasms	Altered Intercellular Communication	Parathyroid hormone-related protein in hypercalcaemia associated with haematological malignancy.	8790147
Inflammation, Erysipelas	Altered Intercellular Communication	The incidence and severity of secondary acute inflammation (erysipelas) were also sharply reduced (p < 0.01).	8792965
Interstitial inflammation, Alveolitis	Altered Intercellular Communication	BAL cytology invariably showed lymphocytic alveolitis while transbronchial biopsy revealed active interstitial inflammation in only one patient.	8793260
Inflammation, Postoperative Hemorrhage	Altered Intercellular Communication	Postoperative bleeding was not correlated with the international normalized ratio (INR), but with degree of local inflammation.	8794658
Inflammatory Bowel Diseases, Retinal Vasculitis, Gastrointestinal inflammation	Altered Intercellular Communication	It may suggest that intestinal inflammation mainly affects arterial endothelial cells and support the theory that intestinal vasculitis is involved in the pathogenesis of inflammatory bowel disease.	8794794
Inflammation, Breast Carcinoma	Altered Intercellular Communication	The significance of inflammation in carcinoma of the breast is controversial.	8795584
Inflammation, Carcinoma	Altered Intercellular Communication	Little attention has been paid to different patterns of inflammation or inflammation associated with different histological types of carcinoma.	8795584
Inflammation, Breast Carcinoma	Altered Intercellular Communication	We have looked at the pattern of inflammation in 123 invasive mammary carcinomas (including 46 lobular), and characterised the inflammatory cells with immunohistochemistry in 21.	8795584
Inflammation, Infiltrating duct and lobular carcinoma	Altered Intercellular Communication	We found different patterns of inflammation in ductal and lobular carcinoma.	8795584
Inflammation, Ductal Carcinoma	Altered Intercellular Communication	Diffuse inflammation was seen more in ductal carcinoma, particularly of high grade, and was predominantly composed of macrophages and T cells.	8795584
Inflammation, Ductal Carcinoma, Neoplasms	Altered Intercellular Communication	Perilobular inflammation was seen most frequently in lobular and high-grade ductal carcinomas, particularly at the tumour edge.	8795584
Inflammation, Neoplasms	Altered Intercellular Communication	Perivascular inflammation was also largely at the tumour edge, but was not more common in any tumour type.	8795584
Inflammation	Altered Intercellular Communication	In contrast to the diffuse inflammation, the perivascular and perilobular inflammation was composed of T and B cells.	8795584
Pituitary hormone deficiencies	Altered Intercellular Communication	Finally, puberty seems to play an important role in the increase of pituitary size in multiple pituitary hormone deficiency and isolated GH deficiency patients.	8796134
Angular, Failure (biologic function)	Altered Intercellular Communication	Thus, a failure in synaptic transmission may precede tangle formation.	8797530
Ulcer, Inflammation, Colitis	Altered Intercellular Communication	A follow-up study was done of relapse rates and progression of inflammation in 571 non-selected patients with ulcerative and indeterminate colitis.	8797653
Proctitis, Inflammation	Altered Intercellular Communication	In relapsing proctitis, 52 percent developed more extensive inflammation.	8797653
Inflammation, Dermatomyositis, Muscle Cells	Altered Intercellular Communication	Chronic inflammation seems to play a major role in skin and muscle cell damage in dermatomyositis.	8800304
Inflammation	Altered Intercellular Communication	The incidence of scintigraphic abnormality in the patients with active inflammation (7 of 21 patients, 33%) was lower than that in the patients in the chronic stage (22 of 32, 69%) (p < 0.02).	8800451
Inflammation	Altered Intercellular Communication	The lower incidence of scintigraphic abnormality in the patients with active inflammation suggests that in the acute phase no stenotic or occlusive changes in the pulmonary artery have yet been produced.	8800451
Inflammation, Virus Diseases, Granuloma, Crohn Disease	Altered Intercellular Communication	Recent studies have shown inflammation of the submucosal microvascular endothelium and granulomata, and endothelial cell cytoplasmic inclusions, consistent with paramyxovirus, were identified by electron microscopy suggesting a persistent measles virus infection in Crohn's disease.	8801199
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	IL8 protein in the mucosa correlated significantly with macroscopic inflammation in Crohn's disease (r = 0.47, p < 0.001) and in ulcerative colitis (r = 0.60, p < 0.001).	8801200
Inflammatory Bowel Diseases, Inflammatory disease of mucous membrane	Altered Intercellular Communication	IL8 is produced mainly in the lamina propria of the colon in inflammatory bowel disease and correlates with mucosal inflammation.	8801200
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Liver biopsy specimens were scored using a histological activity index for liver inflammation and fibrosis.	8801210
Inflammation, Thrombosis, Dental Plaque, Hyperplasia	Altered Intercellular Communication	The major pathologic findings were thrombosis, inflammation of the superficial plaque layers, and neointimal hyperplasia which often coexisted within a same sample.	8803583
Inflammation, Angina, Unstable, Blood Clot, Hyperplasia	Altered Intercellular Communication	This observation questions on the pathogenetic role of thrombus in unstable angina and calls for further investigations on inflammation and neointimal hyperplasia, as well as on the the reciprocal relation between these findings which are often combined within a same lesion.	8803583
Autosomal recessive inheritance	Altered Intercellular Communication	Succinic semialdehyde dehydrogenase (SSADH) deficiency is an autosomal recessive disease involving the catabolism of the neurotransmitter gamma-aminobutyric acid (GABA).	8803774
Airway structure, Bronchial Hyperreactivity	Altered Intercellular Communication	This study investigates the relationship of asthmatic bronchial hyperresponsiveness (BHR), a marker of airway inflammation, and pulmonary function to ambient levels of summertime air pollution.	8804930
Airway structure	Altered Intercellular Communication	This suggests that changes in airway inflammation underlie the increased respiratory morbidity known to accompany pollution episodes.	8804930
Communicable Diseases, Inflammation	Altered Intercellular Communication	In older patients C-reactive protein (CRP) and neopterin have proved useful serum markers of infection and inflammation.	8809148
Inflammation, Arthritis	Altered Intercellular Communication	Disturbed purine metabolism in inflammatory arthropathies may reflect a component in the pathophysiology of inflammation.	8809438
Inflammation	Altered Intercellular Communication	However, despite good oral hygiene, gingival inflammation recurred at regular intervals.	8811475
Inflammation, Arteritis	Altered Intercellular Communication	Kawasaki disease is a syndrome characterized by multiple organ system inflammation and diffuse arteritis.	8811576
Inflammation, Arthritis	Altered Intercellular Communication	He had previously gone to another hospital, where x-rays of the knees and legs reportedly showed inflammation and arthritis.	8814117
Inflammation, Exophthalmos, Ophthalmoplegia	Altered Intercellular Communication	Standardised echography is a safe and non-invasive method of diagnosing VSO in patients presenting with signs of proptosis, ophthalmoplegia, and inflammation of the conjunctiva.	8814742
Inflammation, Granulomatous prostatitis	Altered Intercellular Communication	Granulomatous prostatitis may cause a relatively mild and transient increase in serum PSA level which resolves when the inflammation subsides.	8814847
Granulomatous prostatitis, Malignant Neoplasms	Altered Intercellular Communication	To evaluate serum prostate-specific antigen (PSA) levels in patients with granulomatous prostatitis, an inflammatory condition that can clinically mimic malignancy.	8814847
Inflammation	Altered Intercellular Communication	The biopsies were paraffin embedded, sectioned and stained with hematoxylin and eosin (H and E) to grade the inflammation.	8814977
Inflammation	Altered Intercellular Communication	Inflammation was seen in 98.5% of 595 patients with suitable biopsies.	8814977
Inflammation	Altered Intercellular Communication	In 74.5% of these patients the inflammation was active; 37.5, 32.5 and 4.5% had mild, moderate and severe active inflammation, respectively.	8814977
Inflammation	Altered Intercellular Communication	Both case 3 and 4 were a 20-year-old man and 16-year-old female who had typical findings of pulmonary sequestration with inflammation and easily detection of aberrant artery by CT or aortography.	8815256
Presenile dementia, Inflammation, Abnormal prostate morphology, Vascular Diseases	Altered Intercellular Communication	It could not be established in this study whether or not these hemostatic abnormalities play a casual role in the pathogenesis of dementia, or whether they are secondary to inflammation and chronic vascular disease.	8815562
Alzheimers Disease", senile, Data types - Address, Inflammation	Altered Intercellular Communication	Alzheimer's disease (AD) is found to have striking brain inflammation characterized by clusters of reactive microglia that surround senile plaques.	8815885
Intra-abdominal	Altered Intercellular Communication	Intra-abdominal panniculitis is a tumour-like inflammatory condition of adipose tissue.	8818690
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	However, XS had a more apparent positive influence on the external respiratory function, degree of allergy and unspecific inflammation, as well as on general clinical effectiveness.	8819954
Communicable Diseases, Inflammation	Altered Intercellular Communication	It is likely that the reduction of VIP binding sites in CF is secondary to infection and inflammation.	8820247
Hypertrophic Cardiomyopathy	Altered Intercellular Communication	In summary, there is no evidence for a distinctive hemodynamic or hormonal response to food in hypertrophic cardiomyopathy patients with postprandial symptoms.	8821423
Interstitial inflammation	Altered Intercellular Communication	Transbronchial lung biopsy was done, and examination of the specimen revealed an organizing exudative reaction in the alveolar spaces, as well as interstitial inflammation.	8821999
Neonatal Gastrointestinal Bleeding, AE, Meckel Diverticulum, Inflammation	Altered Intercellular Communication	Approximately 4% of patients with Meckel's diverticula develop complications, most commonly obstruction, gastro-intestinal bleeding and inflammation.	8822071
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Scintigraphic evaluation of the severity of inflammation of the joints with 99TCm-HIG in rheumatoid arthritis.	8822752
Arthritis	Altered Intercellular Communication	A prospective study was carried out to determine the usefulness of 99TCm-human immunoglobulin G (HIG) scintigraphy in the assessment of the severity of joint inflammation.	8822752
Arthralgia, Inflammation, Joint swelling	Altered Intercellular Communication	Both the visual and the quantitative scintigraphic indices correlated significantly with the clinical index, the number of painful joints, the number of swollen joints and several biological markers of inflammation.	8822752
Inflammation, Synovitis	Altered Intercellular Communication	In conclusion, 99Tcm-HIG scintigraphy is an objective test to detect synovitis and to assess the severity of inflammation.	8822752
Inflammation	Altered Intercellular Communication	It is characterized by the presence of inflammation and a marked fibrotic response.	8823237
Arthralgia, Inflammation, Bone pain	Altered Intercellular Communication	We describe a case of poststreptococcal rheumatic syndrome in a 63-year-old woman to highlight that prolonged bone pain, night sweats, arthralgia, and laboratory evidence of active inflammation may be the principal manifestations, and that it may occur even in elderly patients.	8823712
Inflammation, Neoplasms, Neoplasms, Vascular Tissue, Fibrosis	Altered Intercellular Communication	Tumors were also studied for differentiation, keratinization, nuclear atypia, growth pattern, inflammation, desmoplasia, vascular tumor emboli, and DNA content.	8826923
MS gene	Altered Intercellular Communication	It has long been suspected that hormonal factors contribute directly and indirectly to the etiology and pathogenesis of multiple sclerosis (MS).	8828057
Parkinson Disease, Parkinsonian Disorders	Altered Intercellular Communication	It is believed that in this patient Parkinsonism may have existed in a subclinical form and that acute stress, which previously has been shown to precipitate symptoms of Parkinson's disease, triggered the onset of Parkinsonism by further reducing dopaminergic and serotonergic neurotransmission in the basal ganglia.	8828058
Inflammation, Ulceration, CTCAE, Ulcer	Altered Intercellular Communication	Ulcers were graded based on the extent of corneal thinning, degree and extent of ulceration, and amount of inflammation.	8828302
Inflammation	Altered Intercellular Communication	The anastomotic site on the left anterior descending artery showed slight thickness of the internal lumina and chronic inflammation.	8828372
Airway structure, Asthma	Altered Intercellular Communication	In non-atopic asthma, viral airway infection, as well as chronic eosinophilic inflammation of the airways, may cause some trouble in the impaired lymphocyte surveillance and may be especially liable to develop autoantibodies under those circumstances.	8831170
Tumor necrosis, Pneumonitis	Altered Intercellular Communication	Interleukin-8 (IL-8), a potent neutrophil chemoattractant induced by cytokines, including tumor necrosis factor-alpha (TNF), is found in increased concentrations in bronchial alveolar lavage fluid (BALF) in lung inflammation.	8831305
Refractory anemias, Inflammation	Altered Intercellular Communication	Analyses of the TCRBV5, 13 and 17 gene families, which have been reported to be increased in RA patients, showed: (a) the three TCRBV transcripts have common features of BJ gene usage; (b) TCR transcripts from each TCRBV family display a distinctive BJ gene profile, which is displayed better by CD4+ than CD8+ lymphocytes; (c) the BJ gene repertoires of monozygotic twins are more similar than those of unrelated individuals; and (d) the inflammation of RA does not induce specific changes in the genetically determined pattern of BJ expression.	8833908
Inflammation, Necrosis	Altered Intercellular Communication	According to Knodell's HAI scoring system, the scores of periportal inflammation and necrosis (category I) and the scores of intralobular inflammation and necrosis (category II) were similarly higher in Fas antigen-positive cases than in Fas antigen-negative cases (p < 0.01), and there was a positive correlation between these scores and the degree of Fas antigen expression.	8834017
Inflammation	Altered Intercellular Communication	We conclude from this study that sarcoid inflammation is associated with an increased and concerted release of monocyte/macrophage-derived cytokines not only in the lung but also in the peripheral blood.	8834333
Communicable Diseases, Inflammation	Altered Intercellular Communication	Taking into consideration interaction between reflux and infection it was proved that bacterial factor (Helicobacter pylori) acts on gastric mucous membrane (except chronic superficial inflammation) from 2.3 to 30.1(!)	8834665
Inflammation	Altered Intercellular Communication	times higher (depending on form of chronic inflammation) than duodenal-gastric reflux.	8834665
Inflammation	Altered Intercellular Communication	At review, HLA-B27 was significantly more prevalent in patients with persistent locomotor inflammation compared to patients in clinical remission, while HLA-BW62 was predominant in the latter group.	8835560
Crohn Disease, Inflammation	Altered Intercellular Communication	This confirms the hypothesis that some of these patients with SpA initially have a form of subclinical Crohn's disease, of which locomotor inflammation is the only clinical expression.	8835560
Inflammation	Altered Intercellular Communication	HLA-B27 positivity predisposes to a more severe course of locomotor inflammation, while HLA-BW62 has a protective effect but is associated with gut inflammation.	8835560
Inflammation, Spondylitis	Altered Intercellular Communication	In the groups with normal gut histology and with chronic gut inflammation, patients with ankylosing spondylitis (AS) and non-AS-SpA were present in equal numbers.	8835561
Inflammatory Bowel Diseases, Inflammation, Idiopathic chronic inflammatory bowel disease	Altered Intercellular Communication	Eight patients developed idiopathic inflammatory bowel disease (IBD), one with initially acute gut inflammation, 7 with initially chronic gut inflammation.	8835561
Inflammation, Arthritis, Reactive, PHB2 gene	Altered Intercellular Communication	Acute gut inflammation was predominant in patients with reactive arthritis (ReA).	8835561
Inflammation, Crohn Disease	Altered Intercellular Communication	Ten had chronic gut lesions, suggesting this type of gut inflammation is related to the inflammation of Crohn's disease.	8835561
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	This type of gut inflammation, the persistence of high inflammatory serum variables, and the absence of HLA-B27 in patients with AS are risk factors for developing IBD.	8835561
Inflammation	Altered Intercellular Communication	Of the 33 patients with persistent locomotor inflammation, 14 had persistent inflammatory gut lesions, predominantly the chronic type.	8835562
Inflammation, Exacerbation of cGVHD, Arthropathy	Altered Intercellular Communication	In the 11 patients with more than 2 consecutive ileocolonoscopies, clinical remission was always associated with normal gut histology, and flares of the joint disease were related temporally to the reappearance of gut inflammation.	8835562
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Absence of gut inflammation in the SpA is a good prognostic indicator, since gut inflammation or IBD never develops in these patients.	8835562
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Evolution of non-AS-SpA to full blown AS or of uncomplicated SpA to a form of IBD was always associated with gut inflammation at disease onset.	8835562
Rheumatoid Arthritis, Infection	Altered Intercellular Communication	Syndrome of inappropriate secretion of antidiuretic hormone in elderly patients with rheumatoid arthritis associated with infections: report of two cases.	8835600
Visual Impairment, hormone deficiency, Optic Nerve Hypoplasia, Arachnoid Cysts	Altered Intercellular Communication	We describe a 5-month-old boy with bilateral optic nerve hypoplasia associated with visual impairment, growth hormone deficiency and an arachnoid cyst in the right temporal lobe on MRI.	8836508
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Light microscopy of the removed conduits showed severe, sometimes transmural inflammation with submucosal fibrosis.	8837250
Degenerative polyarthritis, Inflammation, Gout	Altered Intercellular Communication	Recently gout has been recognized as a cause of inflammation in patients with nodal osteoarthritis.	8837272
Degenerative polyarthritis, Inflammation, Gout	Altered Intercellular Communication	Whenever a patient with inter-phalangeal joint osteoarthritis presents with an acute episode of inflammation the possibility of gout should be considered.	8837272
Inflammatory Bowel Diseases, Acute and chronic inflammation	Altered Intercellular Communication	The present data show that the number of intestinal mast cells and eosinophils is altered in patients with inflammatory bowel diseases, suggesting that both cell types are involved in the pathogenesis of chronic intestinal inflammation.	8838115
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The unencapsulated mass generally occurred anterior or superior to the fossa ovalis, and histologically was characterized by mature fat with varying quantities of fetal fat, inflammation and fibrosis, and entrapment of myocardial fibers with cytologic atypia.	8838469
Inflammation	Altered Intercellular Communication	These results support the hypothesis that persistent and recurrent inflammation in the nasopharynx spreads through the ET to play a role in the pathogenesis of chronic OM in children.	8839073
Inflammation, Acute inflammation	Altered Intercellular Communication	Histological findings were acute superficial inflammation with neutrophilic infiltration into the dermis.	8839239
Inflammation, Duodenal Ulcer	Altered Intercellular Communication	The grade of inflammation in duodenal ulcer specimens was significantly higher in the antrum than in the corpus (P < 0.01).	8840245
Inflammation, Gastritis	Altered Intercellular Communication	No significant difference in endoscopic findings, H. pylori density or the grade of inflammation was found between the antrum and corpus in patients with gastritis.	8840245
Tolosa-Hunt Syndrome, Necrotizing granulomatous inflammation, Methylated spirit	Altered Intercellular Communication	Tolosa-Hunt syndrome (THS) is characterized by painful ophthalmoplegia due to idiopathic granulomatous inflammation of the cavernous sinus.	8840763
Inflammation, Uveitis	Altered Intercellular Communication	Anterior uveitis was the most frequent anatomical type of intraocular inflammation (49.12%); intermediate uveitis was diagnosed in 12.42% of all the cases and showed an increased incidence over the years (p < 0.0001).	8841072
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Niacinamide improved the global impact of osteoarthritis, improved joint flexibility, reduced inflammation, and allowed for reduction in standard anti-inflammatory medications when compared to placebo.	8841834
Inflammation	Altered Intercellular Communication	The resected colon showed granulomatous inflammation with numerous histiocytes containing pale, oval yeasts of HC.	8842180
Inflammation, Asthma	Altered Intercellular Communication	Airway function correlates with circulating eosinophil, but not mast cell, markers of inflammation in childhood asthma.	8842552
Inflammation, Asthma	Altered Intercellular Communication	It further supports the notion that childhood asthma has a similar immunopathology to that occurring in adults, with predominance of eosinophil mediated inflammation.	8842552
Inflammation, Asthma	Altered Intercellular Communication	Asthmatic inflammation results in increased oxygen free radical generation and assessment of the activity of the selenium (Se) dependent anti-oxidant enzyme, glutathione peroxidase (GSH-Px) in asthma may therefore be important.	8842559
Inflammation, Asthma, Atopy	Altered Intercellular Communication	To test the hypothesis that reduced GSH-Px activity and Se intake contribute to asthmatic inflammation, platelet and whole blood GSH-Px activities and serum and whole blood Se concentrations were measured and compared in atopic and non-atopic asthmatic patients and non-asthmatic control subjects.	8842559
Gastric mucosa, Hemorrhage, Inflammation, Meckel Diverticulum	Altered Intercellular Communication	Aim of this study was to establish the aetiopathogenesis of inflammation and consequent haemorrhage in Meckel's diverticulum with heterotopic gastric mucosa.	8842839
Inflammation, Adenovirus Infections	Altered Intercellular Communication	Tissue removed at the time of resection will be analyzed for evidence of adenovirus infection, thymidine kinase expression and signs of inflammation.	8844206
Mitral Valve Insufficiency, Inflammation, Myocardial Infarction	Altered Intercellular Communication	Cardiac involvement may include ST-T changes, PR prolongation, mild mitral regurgitation, and perivascular inflammation with myocardial necrosis.	8844306
Perivascular inflammation, Myocarditis, Atrial standstill, Electrocardiogram: myocardial infarction (finding), Tricuspid Valve Insufficiency, Congestive heart failure	Altered Intercellular Communication	Work-up of the patient revealed abdominal scar, positive tsutsugamushi antibody, congestive heart failure with severe mitral and tricuspid regurgitation, persistent atrial standstill on electrophysiologic study, junctional rhythm and ST-T changes mimicking anterior myocardial infarction and myocardial inflammation with perivasculitis on endomyocardial biopsy.	8844306
Inflammation, Disorder of eye, TAO brand of troleandomycin, Hashimoto Disease, Thyroid Diseases, Ocular muscular dystrophy, Thyroiditis, Graves Disease	Altered Intercellular Communication	Tests were positive, with EOM cells, in 65% of patients with TAO, 75% with ocular myopathy, a variant of TAO in which periorbital inflammation is minimal, 50% with euthyroid Graves' disease defined as ophthalmopathy associated with subclinical thyroiditis and in 50% of patients with stable lid lag and retraction but no other signs of progressive ophthalmopathy, but in only 13% of patients with Graves' hyperthyroidism without ophthalmopathy, 10% with Hashimoto's thyroiditis and 14% of patients with other thyroid disorders.	8844451
Inflammation, Edema	Altered Intercellular Communication	The ring plaques contained lactate signals indicating oedema, inflammation, and macrophage invasion, and may be transition forms between acute oedematous lesions and chronic demyelinated plaques.	8845254
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	This study demonstrated that abdominal aortic aneurysms are associated with a marked angiogenic response, which is related to the degree of inflammation within the aortic wall.	8846184
Meningioma, Inflammation	Altered Intercellular Communication	The authors describe the unusual case of an occipital meningeal lesion in a 25-year-old man in whom they found inflammation of the occipital lobe mimicking lymphoplasmacyte-rich meningioma.	8847571
Inflammation, Dental Plaque	Altered Intercellular Communication	Concerning the frequency of tooth surfaces exhibiting plaque and gingival inflammation there was a considerable decrease from 1973 to 1983, but during the period from 1983 to 1993 there seems to be no improvement.	8849982
Inflammation, Asthma	Altered Intercellular Communication	Eosinophil cationic protein (ECP) has been expected as an index of eosinophilic inflammation in bronchial asthma.	8851311
Inflammation	Altered Intercellular Communication	These results suggested that macrolides suppress chronic inflammatory response except for eosinophil and IgE-dominant inflammation.	8851317
Inflammation	Altered Intercellular Communication	Inflammation characterized by the infiltration of polymorphonuclear cells was significantly (p < 0.01) less pronounced in group 1 (BIAM) than in group 2 (BI) 4 weeks after the end of treatment.	8851875
Inflammation, Swelling, Hypertrophy	Altered Intercellular Communication	Oral examination showed gross fibrous enlargement of gingival without inflammation or swelling.	8851994
Inflammation	Altered Intercellular Communication	The case of a 54-year-old man is reported who suffered from a painful swollen wrist with signs of inflammation.	8852642
Granulomatous inflammation, Caseous necrosis	Altered Intercellular Communication	Histopathological examination showed a granulomatous inflammation without the tuberculosis-typical development of central caseous necrosis.	8854103
Necrotizing granulomatous inflammation, Pigmented purpuric dermatosis	Altered Intercellular Communication	The clinical picture was of pigmented purpuric dermatosis, but histopathologically, they were hemorrhagic granulomatous inflammation of the upper dermis.	8854588
Pneumonitis	Altered Intercellular Communication	At that time, the patient had received systemic corticosteroid (10-40 mg/day of prednisolone) for about three months to reduce pulmonary inflammation.	8854591
Inflammation	Altered Intercellular Communication	The aim of the present study was to analyze the phenotypic properties of gingival T lymphocytes and subsets in patients with chronic inflammatory adult periodontitis (AP) showing various degrees of inflammation and to relate the results to the immunopathogenesis of AP.	8854599
Gingivitis	Altered Intercellular Communication	Moreover, gingival T lymphocyte and subset counts appeared to be related to the severity of gingival inflammation.	8854599
Fibrosis Assessment	Altered Intercellular Communication	Both correlated significantly with histological fibrosis and portal tract inflammation.	8855173
Inflammation, Histoplasmosis, Tuberculosis, Lymphadenitis, Lymphadenopathy, Malignant Neoplasms, Toxoplasmosis	Altered Intercellular Communication	Chronic specific inflammation (tuberculosis, toxoplasmosis, and histoplasmosis) predominated as a cause of lymphadenopathy (44%) compared with non specific lymphadenitis (31%) and malignant tumours (24%).	8855672
Inflammation, Basal cell hyperplasia, Necrosis, Fibrosis Assessment, Granulation finding, Benign prostatic hypertrophy	Altered Intercellular Communication	The histologic findings, in decreasing order of frequency, were: full core fibrosis, necrosis, granulation tissue, basal cell hyperplasia, cell swelling, hemosiderin deposits, chronic inflammation, thick nerves and prostatic hyperplasia.	8857646
Inflammation, "Alzheimers Disease", Angular	Altered Intercellular Communication	Inflammation, A beta deposition, and neurofibrillary tangle formation as correlates of Alzheimer's disease neurodegeneration.	8858005
Synapses, Inflammation, Data types - Address	Altered Intercellular Communication	Compared to NC patients, AD patients exhibited significant cortical synapse loss, A beta deposition, NFT formation, and inflammation.	8858005
Synapses, Inflammation, Hematopoietic stem cells	Altered Intercellular Communication	HPC patients also had significantly elevated A beta deposition and NFT formation, but there was no evidence of synapse loss and little or no evidence of inflammation.	8858005
Pain Distress Question, Visual Impairment, Acute inflammation of orbit, Conjunctival hyperemia	Altered Intercellular Communication	In both groups the most common presentation was a mass with an indolent course; visual impairment was seen in 13%, conjunctival redness in 25%, pain in 12%, and acute orbital inflammation in 15% of the patients.	8858356
Communicable Diseases, Inflammation, pathologic fistula, Carotid Pseudoaneurysm	Altered Intercellular Communication	Self-limited inflammation was the third frequent cause (34 patients, 23%), while carotid aneurysms and fistulas, infection, and other causes composed the remaining 12%.	8859057
Aneurysm, Inflammation, Traumatic injury, Neoplasms	Altered Intercellular Communication	The age at onset varied with the cause, and patients with aneurysms (average age, 52 years) and patients with tumors (average age, 47 years) were older than those with self-limited inflammation (average age, 35 years) and trauma (average age, 29 years).	8859057
Inflammation, Pituitary Apoplexy, Aneurysm	Altered Intercellular Communication	Spontaneous remissions defined "self-limited inflammation" but were also seen following an acute onset of symptoms due to aneurysms and pituitary apoplexy.	8859057
Inflammation, Cavernous sinus syndrome, Neoplasms, Meningioma, Aneurysm, Traumatic injury, Bacterial Infections	Altered Intercellular Communication	In an unselected series from a city hospital, tumor, trauma, and self-limited inflammation were the predominant causes of cavernous sinus syndrome, and classic causes such as aneurysm, meningioma, and bacterial infection were uncommon.	8859057
Inflammation, nervous system disorder, Meningitis, Bacterial, Neurotoxicity Syndromes, neuron death	Altered Intercellular Communication	In addition to other potentially neurotoxic mediators of inflammation, the excitatory amino acid glutamate, which has been implicated in neuronal death in a variety of other neurological diseases, may also be involved in the pathological process of bacterial meningitis.	8859061
Inflammation, Intestinal Obstruction	Altered Intercellular Communication	A rare case of xanthogranulomatous inflammation of the sigmoid colon presenting as intestinal obstruction is reported.	8859170
Inflammation, Intestinal Obstruction	Altered Intercellular Communication	Though rare, xanthogranulomatous inflammation should be considered in patients presenting with large bowel obstruction.	8859170
Inflammation, Adipose tissue loss, Lipoatrophy	Altered Intercellular Communication	Localized loss of adipose tissue without antecedent clinical or histologic inflammation is termed idiopathic lipoatrophy.	8859277
Inflammation, Chronic disease of ear	Altered Intercellular Communication	Nasal inflammation and chronic ear disease in Australian Aboriginal children.	8860389
Chronic otitis media, Eustachian tube disorder, Nasal inflammation	Altered Intercellular Communication	Chronic middle ear disease is common in Aboriginal children, and may be linked to nasal inflammation and Eustachian tube dysfunction.	8860389
Communicable Diseases, Nasal inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	The study reported here was performed to define the role of allergy and infection in causing nasal inflammation in Aboriginal children with chronic middle ear disease.	8860389
Chronic disease of ear, Nasal inflammation, Neutrophil Infiltration	Altered Intercellular Communication	Chronic ear disease in Aboriginal children is associated with nasal inflammation, neutrophil infiltration and the presence of bacteria.	8860389
Respiratory Tract Infections, Acute and chronic inflammation	Altered Intercellular Communication	These features suggest respiratory infection as the main cause of chronic nasal inflammation in Aboriginal children with middle ear disease.	8860389
Communicable Diseases, Inflammation	Altered Intercellular Communication	Topical and systemic antiamebic medications decreased the inflammation but failed to control the infection.	8862062
Communicable Diseases, Inflammation, Decreased translucency, Keratopathy	Altered Intercellular Communication	Infectious crystalline keratopathy is a chronic infection of the cornea, characterized by branching intrastromal opacities without inflammation.	8862934
Communicable Diseases, Inflammation, Candida parapsilosis	Altered Intercellular Communication	Chronic topical corticosteroid use in this patient produced relative immunosuppression, allowing for the infection by Candida parapsilosis and the lack of inflammation in the cornea.	8862934
Communicable Diseases, Burn Specimen Source Codes, Inflammation	Altered Intercellular Communication	The plasma IL-1ra level was closely correlated with the severity of inflammation and the clinical status of the burn patients, regardless of the infection.	8863178
Inflammation, Stenosis	Altered Intercellular Communication	Risk factors for recurrence were etiology (post-transurethral resection and inflammation), stricture longer than 1 cm.	8863550
Inflammation, Fibrosis Assessment, Hepatic Infection, Hepatitis B, Hepatitis C	Altered Intercellular Communication	In sections of liver infected with hepatitis B virus (HBV) or hepatitis C virus (HCV), the expression of CYP2A6 was markedly increased in hepatocytes immediately adjacent to areas of fibrosis and inflammation.	8864187
Hepatic inflammation, Liver Cirrhosis	Altered Intercellular Communication	These results suggest that alterations in phenotypic expression of specific P-450 isoenzymes in hepatocytes associated with hepatic inflammation and cirrhosis might increase susceptibility to AFB genotoxicity.	8864187
Chronic infectious disease, Paraproteinemias, Inflammation, Neoplasms	Altered Intercellular Communication	An extensive search for evidence of chronic infection, inflammation, neoplasms and paraproteinemia was conclusively negative in the other patient.	8864397
Inflammation	Altered Intercellular Communication	No correlation was found between serum levels of anti-H. pylori IgG and of MRP, a novel marker of inflammation.	8865155
Inflammation, Dental Plaque	Altered Intercellular Communication	The robustness of the levels of these components may be due to inflammation associated with the healing process, or to a further plaque induced response.	8866314
Muscular Atrophy, Liver Cirrhosis	Altered Intercellular Communication	Thus, we consider that palmar muscle atrophy in patients with cirrhosis is not due to hormonal excess in serum, but may be attributable to advanced age and diminished physical strength.	8868073
Inflammation, Neoplasms, Chronic disease	Altered Intercellular Communication	The proportion of patients who believed that they had a benign tumor was 25.1%; 12.6% believed they had nonneoplastic disease (inflammation or other chronic disease); 7.5% believed they had precancerous changes; and 17.6% knew nothing about their diagnosis.	8870430
Inflammation, Perforation (observation)	Altered Intercellular Communication	The narrow lumen and narrow base of the diverticulum was thought to be the cause of poor self-emptying and subsequent acute inflammation and perforation.	8870439
allergic inflammation	Altered Intercellular Communication	These results suggest that higher levels of serum sTNF-RI, sTNF-RII and IL-1Ra may reflect up-regulation of TNF-R expression and IL-1Ra production in allergic inflammation, and sTNF-RI, sTNF-RII and IL-1Ra may contribute to regulating TNF-alpha- and IL-1-mediated production and development of allergic inflammation.	8870701
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	These results suggest that mast cells (MC), in association with various inflammatory cells, may contribute to inflammation and cartilage breakdown in osteoarthritis (OA).	8871262
Inflammation, Lesion of liver, Malignant neoplasm of liver, Chronic infectious disease, Communicable Diseases, Hepatobiliary Disorder, Hepatitis C	Altered Intercellular Communication	Chronic infection with the hepatitis C virus (HCV) may lead to a variety of hepatic lesions from benign inflammation to liver cancer, but the relationships between infection and development of liver disease are poorly understood.	8871879
Retinal Detachment, Intraocular inflammation, Corneal edema, Vitreous Hemorrhage	Altered Intercellular Communication	Initial ocular findings in 52 patients included moderate or severe corneal edema in 23 cases (44%), intraocular pressure greater than 25 mm Hg in 24 (46%), intraocular inflammation in 36 (69%), retinal detachment in 2 (4%) and vitreous hemorrhage in 4 (8%).	8872375
Liver Cirrhosis, Necrosis with inflammation	Altered Intercellular Communication	Persistence of HBV-DNA episomic forms, necro-inflammation in the liver, and cirrhosis appear to be additional promoting factors.	8875610
Inflammation, Cystitis, Ulcerative Colitis, Inflammatory disorder, Asthma	Altered Intercellular Communication	Such noninvasive methods may be useful not only to explore the role of NO in inflammation and host defence, but also in the diagnosis and monitoring of inflammatory mucosal diseases such as asthma, ulcerative colitis and cystitis.	8876755
Enteritis	Altered Intercellular Communication	Comparison of Tc-99m dextran, Tc-99m citrate, and Tc-99m human immunoglobulin G. A 60-year-old man with localized small bowel inflammation underwent abdominal scintigraphy with Tc-99m human polyclonal immunoglobulin G and two experimental inflammation-seeking agents, Tc-99m dextran and Tc-99m citrate.	8879867
Inflammation	Altered Intercellular Communication	The authors conclude that Tc-99 dextran and Tc-99 citrate are clinically suitable inflammation-seeking agents that need further evaluation, especially for locating abdominal inflammations.	8879867
Inflammation	Altered Intercellular Communication	The authors conclude that Tc-99 dextran and Tc-99 citrate are clinically suitable inflammation-seeking agents that need further evaluation, especially for locating abdominal inflammations.	8879867
Uveitis	Altered Intercellular Communication	A 13 year-old boy had uveitis and symptoms of unilateral periglobular orbital inflammation, confirmed by computed tomography.	8881183
Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	To determine the vitamin E status of subjects with, and without, gastroduodenal inflammation and Helicobacter pylori infection.	8881804
Inflammation	Altered Intercellular Communication	These findings may reflect a mobilisation of antioxidant defences to the sites of maximal inflammation in the stomach.	8881804
Inflammation, Disorder of the genitourinary system, Necrosis, Arthritis, Vasculitis of the skin	Altered Intercellular Communication	We advocate ANCA testing in patients presenting with limited urogenital disease in association with a past or present relevant history of arthritis, skin vasculitis and/or biopsies showing necrosis or non-specific inflammation.	8881941
Inflammation, Heart failure, Neoplasms	Altered Intercellular Communication	Increased numbers of endocrine cells, often in the form of large abnormal aggregates, were present in 17 pairs of tumour-bearing lungs where they were associated not with the tumour but with non-tumoral pathology, especially inflammation and changes associated with cardiac failure.	8882080
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Pathologic examination showed marked thickening of the esophageal wall by submucosal pseudodiverticula typical of esophageal intramural pseudodiverticulosis (EIPD) and extensive mucosal and submucosal chronic inflammation and fibrosis.	8882356
Inflammation, TRPV6 gene	Altered Intercellular Communication	Taken together, these results indicate that there are two sources of increased plasma M-CSF concentration in ATL; ATL cells themselves and normal parenchymal cells that cause this increase as the result of elevated body temperature due to inflammation.	8882959
Myelofibrosis, Inflammation, Communicable Diseases, Malignant Neoplasms, Compression fracture, Paget Disease	Altered Intercellular Communication	There were 22 malignancies; four isolated compression fractures, two at T6, one at T7, one at T8; four cases of infection or inflammation; and one case each of Paget's disease and myelofibrosis.	8883208
Refractory anemias, Inflammation, Abnormality of primary teeth	Altered Intercellular Communication	We conclude that we find no evidence of a cell lineage-specific or a disease-specific abnormality of proto-oncogene products in RA, and the expression of these oncoproteins is consistent with inflammation rather than with any primary abnormality of cell growth.	8883430
Inflammation	Altered Intercellular Communication	The volume is related to clinical signs of inflammation, but may also give information about the cumulated synovial proliferation in the joint.	8883434
Inflammation, Cholangitis	Altered Intercellular Communication	We created a biliary tract infection score (BTIS) including local physical and ultrasound findings, signs of inflammation and hepatobiliary involvement.	8884291
Inflammation, Periodontitis	Altered Intercellular Communication	Efficacy of a sonic toothbrush on inflammation and probing depth in adult periodontitis.	8884648
Inflammation, Periodontal Diseases	Altered Intercellular Communication	Under these conditions, there is some evidence to suggest that the sonic toothbrush is more beneficial in resolving inflammation in patients with moderate periodontal disease.	8884648
Tears body substance, Rupture	Altered Intercellular Communication	In all cases, the surgical findings confirmed the ultrasonographic diagnoses: 3 inflammations, 4 partial tears, and 10 ruptures.	8886783
Tumor necrosis, Arthritis	Altered Intercellular Communication	Cytokines such as IL-1 and tumor necrosis factor alpha (TNF alpha) play a critical role in chronic joint inflammation and destruction.	8886998
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Tissue superoxide dismutase (SOD) activity and immunohistochemical staining in acute appendicitis: correlation with degree of inflammation.	8887028
Inflammation, Phlegmonous, Gangrene	Altered Intercellular Communication	These results indicated that active oxygen influences the degree of inflammation in phlegmonous and gangrenous appendicitis.	8887028
Gingivitis, Dental Plaque	Altered Intercellular Communication	The purpose of this clinical trial was to compare the effectiveness and safety of a new dental flossing device (Quik Floss) to finger flossing in plaque removal, reduction of gingival inflammation and patient preference.	8891940
Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	In conclusion, Quik Floss is a safe and effective oral hygiene measure for reducing plaque, inflammation and bleeding over time.	8891940
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Recent evidence suggests that inflammation in the central nervous system plays an important role in the pathogenesis of Alzheimer's disease.	8892348
Necrotizing granulomatous inflammation	Altered Intercellular Communication	This finding indicates that at least these four cytokines are involved in the cytokine network at the local alveolar site of chronic granulomatous inflammation.	8893383
Necrotizing granulomatous inflammation	Altered Intercellular Communication	This study adds a report to the literature that supports a role for cytokine, TNF-alpha, IL-6, PDGF and GM-CSF in particular, in the promotion and maintenance of sarcoid granulomatous inflammation.	8893383
Inflammation	Altered Intercellular Communication	The results were consistent with granulation tissue and chronic inflammation.	8894815
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	These results suggest that mast cells in association with various inflammatory cells, may contribute to inflammation and cartilage breakdown in OA.	8895218
Fibrosis Assessment	Altered Intercellular Communication	There is increasing evidence for the association of mast cells with angiogenesis, chronic inflammatory conditions and fibrosis.	8897010
Inflammation, Edema	Altered Intercellular Communication	When edema and inflammation occurred in peritumoral regions, lymphatics showed a dilated lumen, non-indented wall with dissociated perivascular collagen and elastic fibers.	8897356
Inflammation	Altered Intercellular Communication	Roles of preceding infection/inflammation and recent psychological stress.	8898805
Inflammation, Cerebrovascular accident, Brain Infarction	Altered Intercellular Communication	We examined the temporal relationship between preceding infection/inflammation and stroke onset as well as the role of recent psychological stress as a potential precipitant for brain infarction.	8898805
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	The prevalence of infection/inflammation was significantly higher in the stroke group only within the preceding 1 week compared with either community control subjects (13/37 versus 6/47, P < .02) or hospitalized neurological patient controls (3/34, P < .02).	8898805
Inflammation, Chills, CTCAE, Fever, CTCAE, Cerebrovascular accident	Altered Intercellular Communication	A substantial proportion of stroke patients with preceding (< 1 week) infection/inflammation (5/13) had no accompanying fever or chills.	8898805
Inflammation, Histiocytoma, Angiomatoid Fibrous, Neoplasms	Altered Intercellular Communication	The alternative diagnosis of angiomatoid malignant fibrous histiocytoma was considered for these two cases but was excluded because the tumors were partly dermal, had a well-defined storiform pattern, and lacked large blood lakes, multinodularity, a fibrous pseudocapsule, and surrounding chronic inflammation.	8898840
Motor Neuron Disease	Altered Intercellular Communication	Serotonergic neurotransmission in the spinal cord and motor cortex of patients with motor neuron disease and controls: quantitative autoradiography for 5-HT1a and 5-HT2 receptors.	8899664
Inflammation, Hyperplasia	Altered Intercellular Communication	Additionally, in cases of chronic ITBFS seen in young elite athletes, synovial tissue taken from this lateral synovial recess reveals histological evidence of inflammation and hyperplasia that suggests its involvement in the pathological process.	8902132
Chronic Obstructive Airway Disease	Altered Intercellular Communication	Cigarette smoking produces peripheral airway inflammation in all smokers, and chronic airways obstruction in approximately 20% of heavy smokers.	8902456
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Disease severity was expressed as a histological score (which included grading of portal inflammation, lobular activity, fibrosis, and cytopathic changes).	8903372
Sepsis, Inflammation, Respiratory Distress Syndrome, Adult, Hypoxia	Altered Intercellular Communication	As the result of tissue hypoxia or inflammation, the lungs of patients with sepsis and ARDS may become a source of lactate release into the circulation.	8904278
vascular inflammations, Septicemia	Altered Intercellular Communication	The findings suggest an increased production or release of ICTP in Gram-negative septicaemia, presumably owing to an alteration of extracellular matrix during septicaemia-related vascular inflammation.	8904353
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	These results suggest that the monocyte-derived cytokines IL-1beta and IL-6 are mediators of inflammation in inflammatory bowel disease.	8904520
Refractory anemias, Inflammation, ER-overload response	Altered Intercellular Communication	To compare the synovial fluid (SF) levels of these ILs, and their relationship to local inflammation as well as the acute phase response, erythrocyte sedimentation rate (ESR) and serum C-reactive protein (CRP) in the two RA subsets, we determined white blood cell (WBC) number, total protein (TP), IL-1beta, IL-6 and IL-8 concentrations in the SF of 50 patients, 15 with EORA and 35 with YORA.	8904958
Seizures, Ischemia	Altered Intercellular Communication	Release of the neurotransmitter glutamate after seizures or brain ischemia may damage postsynaptic neurons by increasing calcium flux through N-methyl-D-aspartate (NMDA) receptor-gated ion channels.	8904965
Inflammation	Altered Intercellular Communication	The occurrence of 25F9-positive macrophages, typical of the late phase of inflammation, varied widely in the biopsies.	8905111
Helicobacter pylori, Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	It is thought that Helicobacter pylori colonization of the gastric mucosa might stimulate the production of several cytokines, which might trigger and maintain the gastric inflammation associated with Helicobacter pylori infection.	8905454
Infection caused by Helicobacter pylori	Altered Intercellular Communication	Helicobacter pylori infection results in a local increase in interleukins-1 beta and -6 and interleukin-2 receptor associated with high-grade mucosal inflammation.	8905454
Inflammation, Demyelination, Muscular Dystrophy, Duchenne	Altered Intercellular Communication	We consider that the patient had the clinical features of "multifocal pseudohypertrophic neuropathy" described by Adams et al, and that chronic demyelination and inflammation associated with impairment of the blood-nerve barrier might be underlying mechanisms.	8905985
Inflammation, Pancreas	Altered Intercellular Communication	The disease appears to be caused by a deficit of pancreatic stabilizing proteins that leads to precipitation of solutes contained in the pancreatic secretions; these precipitates are the cause of inflammation.	8906670
Detrusor instability, Inflammation, Prostate	Altered Intercellular Communication	Fifty-two consecutive patients with prostatism who underwent a prostatectomy were investigated with regard to irritative symptom score, age, prostate volume, urine culture results, degree of detrusor instability, inflammation in the prostate, and stromal, glandular or mixed prostatic histopathology.	8908653
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Skin biopsy showed chronic granulomatous inflammation of the dermis which contained septate hyphae and large spores mainly free.	8909032
Inflammation, Rupture, atherosclerotic, Aneurysm	Altered Intercellular Communication	Inflammation precedes erosion and rupture of atherosclerotic atheromas and aneurysms.	8909231
Inflammation, Temporal Arteritis, Inflammatory disorder	Altered Intercellular Communication	The effect of inflammation on arterial structure and remodeling can be studied in primary vascular inflammatory diseases such as in temporal arteritis.	8909231
Hepatic inflammation, Lymphadenopathy, Hodgkin Disease	Altered Intercellular Communication	Sixteen patients without palpable lymphadenopathy who presented with features suggesting hepatic inflammation were found to have non Hodgkin's lymphoma involving the liver.	8909324
Inflammation, Periodontitis, Calculi	Altered Intercellular Communication	The results demonstrate that gingival inflammation and subgingival calculus are associated with early periodontal breakdown, and contradict earlier reports of early-onset periodontitis not being associated with these factors.	8910833
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Direct measurement of gaseous NO in the urinary bladder seems to be an attractive diagnostic method for detection of mucosal inflammation.	8911512
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	Elevated sLFA-3 and sICAM-1 levels might reflect the generalized inflammation in cirrhosis and by interference with cell-cell interactions sICAM-1 and sLFA-3 may limit the extent of inflammation.	8912145
Airway structure, Cystic Fibrosis	Altered Intercellular Communication	Airway inflammation in children younger than 5 yr of age is difficult to assess, particularly in patients with cystic fibrosis (CF).	8912759
Inflammation, Lung diseases	Altered Intercellular Communication	We conclude that: (1) DNA levels were easily quantifiable in BALF of young children; (2) DNA levels in BALF from CF patients were greater than in a group of children with other pulmonary diseases, and that in some infants with CF, BALF DNA levels were equivalent to those of much older patients with CF; (3) DNA levels in BALF correlate with BALF neutrophil number, an index of inflammation; and (4) some infants with CF have increased levels of DNA in BALF, which may justify a clinical trial of aerosolized rhDNase in this population.	8912759
Fibrous, Inflammation, Heart failure	Altered Intercellular Communication	However cardiac failure recurred thereafter because of fibrous epicarditis of tuberculous inflammation.	8913070
Inflammation	Altered Intercellular Communication	There was no correlation between ANA positivity and indicators of joint inflammation.	8914679
Inflammation, Traumatic neuroma	Altered Intercellular Communication	Postoperative pathological examination revealed traumatic neuroma associated with inflammation.	8914682
Inflammation, Fibrosis Assessment, Fatty degeneration, Liver Cirrhosis	Altered Intercellular Communication	Biopsies were classified as: (1) normal, (2) steatosis, (3) inflammation, (4) fibrosis, or (5) cirrhosis.	8915142
Inflammation, Fibrosis Assessment, Fatty degeneration, Liver Cirrhosis	Altered Intercellular Communication	Within this group, levels were significantly higher in patients with inflammation, fibrosis or cirrhosis compared with those with normal histology or steatosis alone (P < 0.0001).	8915142
Inflammation, p-Dimethylaminoazobenzene, Bronchiolitis	Altered Intercellular Communication	Diffuse aspiration bronchiolitis (DAB) is a new term that we proposed to define a clinical entity that is characterized by a chronic inflammation of bronchioles caused by recurrent aspiration of foreign particles.	8915236
Acute and chronic inflammation	Altered Intercellular Communication	Histologic findings of DAB were characterized by localization of chronic mural inflammation with foreign body reaction in bronchioles.	8915236
Granulomatous inflammation, Panniculitis, Vasculitis, CTCAE, Necrosis	Altered Intercellular Communication	In most biopsies, histologic examination revealed lobular or septolobular panniculitis with varying combinations of granulomatous inflammation, primary vasculitis, and necrosis.	8915735
Inflammation, Angiolymphoid hyperplasia	Altered Intercellular Communication	The surrounding liver tissue exhibited chronic inflammation with some peculiar angiofollicular structures mimicking Castleman's disease.	8916149
Inflammation, Erythema, Infection	Altered Intercellular Communication	Twenty-seven patients had signs of local inflammation (erythema or local discharge), and nine of these had infections.	8916814
Catheter infection, Inflammation	Altered Intercellular Communication	The presence of two local signs of inflammation is a strong predictor of local and epidural catheter infection.	8916814
Inflammation, Asthma	Altered Intercellular Communication	Airway epithelial cells are known to produce a granulocyte/macrophage colony-stimulating factor (GM-CSF), which induces eosinophilic inflammation in bronchial asthma.	8918375
Airway structure	Altered Intercellular Communication	Thus, IL-4 and IL-13 may contribute to airway inflammation by upregulating GM-CSF production by bronchial epithelial cells.	8918375
Lesion, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	The rest presented with portal lesions, either inflammation or fibrosis.	8918754
Inflammation, NDUFAB1 gene, Periarticular Route of Administration, Calcified (qualifier)	Altered Intercellular Communication	The diagnosis of ACP is based on the finding of inflammation around a joint along with radiographic evidence of periarticular soft tissue calcifications.	8924143
Pain Distress Question, NDUFAB1 gene, Swelling, Acute calcific periarthritis	Altered Intercellular Communication	Pain and swelling at the first metatarsophalangeal joint can be caused by acute calcific periarthritis (ACP), an inflammatory condition resulting from deposition of hydroxyapatite crystals.	8924143
Inflammation, Hypergammaglobulinemia, Hypoalbuminemia	Altered Intercellular Communication	Serum markers of inflammation were present in most patients: a high level of C reactive protein (90%), polyclonal hypergammaglobulinaemia (89%) and hypoalbuminaemia (56%).	8924253
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histological examination shows perifollicular fibrosis and lymphocytic inflammation concentrated around the isthmus and infundibular areas of the follicles.	8926170
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The expression of IL-8, TNF-alpha and IFN-gamma m-RNA increased even in inactive UC, suggesting that these three cytokines play an important role in the pathogenesis of repeated inflammation of UC.	8926619
Inflammation	Altered Intercellular Communication	The intercellular adhesion molecule-1 (ICAM-1) is important in mediating intercellular contact in inflammation.	8926620
Fever, CTCAE, Granulomatous inflammation, Headache, Weight decreased, Temporal Arteritis	Altered Intercellular Communication	In both cases the early symptoms and signs of disease (headache, fever, weight loss and sedimentation rate raised) were associated to classical histology of temporal arteritis (granulomatous inflammation with giant cells).	8927430
Inflammation	Altered Intercellular Communication	There was no significant correlation between the E-alpha 1PI concentration and other analyzed indicators of inflammation.	8927484
Inflammation	Altered Intercellular Communication	The causes and mechanisms of the changes observed resulting in the chronic inflammation which takes the form of vitium cordis are discussed.	8929134
Gastritis	Altered Intercellular Communication	CagA positive H pylori strains appear to be more aggressive, as reflected by a greater degree of gastric inflammation and higher levels of Il-8 production.	8929480
Inflammation, physiopathological	Altered Intercellular Communication	Thus, main pathological findings associated with tubal dysfunction involved inflammation in the nasopharynx.	8932429
Inflammation	Altered Intercellular Communication	Blood examinations revealed the presence of acute inflammation and an increase of pancreatic enzymes.	8933187
Inflammation, Thrombosis	Altered Intercellular Communication	Although a few inflammatory cells were seen in the thrombosed vessels, inflammation evoked by CPB was mild and did not extend to either the vessel wall or to surrounding tissues.	8933875
Inflammation, Fracture	Altered Intercellular Communication	Only one patient showed recurrence of periapical inflammation 8 yr after operation, probably caused by a root fracture.	8935025
Kimura Disease	Altered Intercellular Communication	Kimura's disease, a chronic inflammatory condition of unknown cause, is endemic in Orientals.	8936520
Inflammation, Low Vision	Altered Intercellular Communication	A 71-year old woman complains of painless inflammation, discharge and decreased vision at the right eye since two weeks.	8936773
Inflammation, Cerebral abscess	Altered Intercellular Communication	All showed CSF inflammation and three developed multiple cerebral abscesses.	8937541
Embolism, Inflammation, Encephalitis, Cerebrovascular accident	Altered Intercellular Communication	One presents with stroke and CNS inflammation (septic embolic focal encephalitis).	8937541
Inflammation	Altered Intercellular Communication	These results suggest a role of NGF autoantibodies and NGF in joint inflammation especially in spondylarthropathies.	8937683
Inflammation, Hepatic inflammation, Hepatitis, Fibrosis Assessment, Hepatitis B, Hepatitis C	Altered Intercellular Communication	Hepatic iron is associated with increased hepatic inflammation in chronic hepatitis B and hepatitis C and with high fibrosis scores in hepatitis C. There is a threshold effect, and once present, increasing iron does not correlate with increasing inflammation or fibrosis.	8938538
Inflammation	Altered Intercellular Communication	However, it cannot be ruled out that these markers solely reflect hyperproliferation associated with active inflammation.	8940998
Inflammation, Ulcerative Colitis, Inflammatory disorder	Altered Intercellular Communication	Ulcerative colitis (UC) is a chronic inflammatory disease of the colon characterized by repeated episodes of inflammation and epithelial regeneration.	8940999
Gastritis	Altered Intercellular Communication	The major complications were gastric and bronchial inflammation due to the corrosive properties of these compounds.	8941204
Growth hormone neurosecretory dysfunction	Altered Intercellular Communication	Growth hormone neurosecretory dysfunction associated with ring chromosome 18.	8942020
Communicable Diseases, Gastrointestinal inflammation, Intestinal Diseases	Altered Intercellular Communication	Protein-losing enteropathy was confirmed by analysis of whole-gut lavage fluid, and intestinal inflammation and infection were excluded.	8942750
Aspergillosis, Allergic Bronchopulmonary, Granulomatous inflammation, Bronchocentric granulomatosis, Asthma, Hypersensitivity	Altered Intercellular Communication	In asthmatic patients it may lead to a hypersensitivity reaction involving eosinophilic infiltration of the bronchial wall and mucoid impaction (a condition called allergic bronchopulmonary aspergillosis) or granulomatous inflammation (bronchocentric granulomatosis).	8943916
Inflammation	Altered Intercellular Communication	Unfortunately in this disease, direct surgery on the conjunctiva often results in marked inflammation and cicatrisation.	8944093
Conjunctivitis	Altered Intercellular Communication	Two patients post-operatively developed severe conjunctival inflammation that required systemic immunosuppression.	8944093
Primary Graft Failure After Hematopoietic Cell Transplantation, Inflammation, Failure (biologic function)	Altered Intercellular Communication	The causes of failure were primary surgical failure (n = 2), progression of cicatrisation secondary to surgically induced inflammation (n = 1), development of misdirected lashes (n = 1) and late recurrence at 7 months (n = 1).	8944093
Conjunctivitis	Altered Intercellular Communication	Activation of severe conjunctival inflammation occurred in 13% of cases and this must be considered pre- and post-operatively.	8944093
Conjunctivitis	Altered Intercellular Communication	Conjunctival inflammation induced the migration of dendritic cells from the stroma to the epithelium and thus increased their density.	8944132
Glaucoma, CTCAE	Altered Intercellular Communication	Conjunctival cells were isolated by conjunctival impression cytology from 150 patients: controls (65 patients, 126 eyes) or with various chronic inflammatory conditions (85 patients, 160 eyes); and by conjunctival biopsies from 25 patients: controls (10 patients) or treated topically for primary open angle glaucoma (15 patients).	8944132
Inflammation, Granuloma	Altered Intercellular Communication	Chalazions represent the most frequent aetiology of inflammation (49%), followed by granuloma (30%).	8944133
Neoplasms, Uterine adnexae structure, Malignant Neoplasms	Altered Intercellular Communication	Benign tumors and the inflammations of the eye and its adnexa are about twice as frequent as malignant tumours.	8944133
Uterine adnexae structure, Neoplasms	Altered Intercellular Communication	Benign tumors and inflammations of the eye and its adnexa corresponded respectively to 25.9% and 7.1% of the histological results accomplished in the laboratory.	8944133
Papilloma, Neoplasms	Altered Intercellular Communication	Papilloma and cysts together account for about 50% of the benign tumors and inflammations of the eye.	8944133
Exophthalmos, Orbital Pseudotumor	Altered Intercellular Communication	After surgery, the orbital inflammation and proptosis resolved, but an irreducible, nonpurulent lacrimal sac mucocele persisted.	8944391
Inflammation	Altered Intercellular Communication	Pathologic examination of the lacrimal sac biopsy specimen showed only chronic nongranulomatous inflammation.	8944391
Inflammation, Pancreatitis, Hemochromatosis, Fibrosis Assessment, Interstitial Fibrosis Assessment, Fatty infiltration	Altered Intercellular Communication	The 45 cases were re-assigned to seven different diagnostic categories: chronic pancreatitis, 21 (47%) cases; interstitial fibrosis with or without chronic inflammation, 11 (24%) cases; repair stage of acute pancreatitis, four (9%) cases; severe fatty infiltration, three (7%) cases; chronic inflammation without interstitial fibrosis, two (4%) cases; haemochromatosis, one (2%) case; and undetermined, three (7%) cases.	8944611
Refractory anemias, Rheumatoid Arthritis, Degenerative polyarthritis	Altered Intercellular Communication	To understand the clinical role of parathyroid hormone-related peptide (PTHrP) in rheumatoid arthritis (RA), we analysed the circulatory and synovial fluid (SF) concentrations of the N- and C-terminal regions of PTHrP (N- and C-PTHrP) in RA (n = 38), osteoarthritis (OA, n = 45) and control (n = 11) subjects.	8948289
Keratosis	Altered Intercellular Communication	Inflammation of solar keratoses following systemic 5-fluorouracil.	8949450
Inflammation, Keratosis, Neoplasms	Altered Intercellular Communication	We report three patients with marked inflammation of the solar keratoses following continuous infusion of 5-FU for solid tumours.	8949450
Inflammation, Peptic Ulcer, Ulcer	Altered Intercellular Communication	Endoscopic biopsy specimens were taken 1-2 cm from areas of active inflammation or ulcer (peptic ulcer patients) or just beyond the duodenal bulb (normals) in 35 consecutive subjects.	8949636
allergic inflammation	Altered Intercellular Communication	This offers the opportunity of studying the fundamentals of allergic inflammation in addition to improvement of knowledge on the basal pathophysiological mechanisms of the disease.	8955576
Inflammation, Myositis	Altered Intercellular Communication	We conclude that in the inflammatory myopathies, T cell inflammation is not cleared by apoptosis and affected muscle fibers do not die by apoptosis.	8957443
Inflammation, Peri-Implantitis	Altered Intercellular Communication	The term "peri-implantitis" is used to describe the formation of deep mucosal pockets around dental implants, inflammation of the peri-implant mucosa, and increased resorption of peri-implant bone.	8957783
Hemorrhage, Inflammatory disease of mucous membrane	Altered Intercellular Communication	However, the group of smokers showed a higher score in the bleeding index, the mean peri-implant pocket depth, the degree of peri-implant mucosal inflammation, and radiographically discernible bone resorption mesial and distal to the implant.	8957783
Communicable Diseases, Inflammation	Altered Intercellular Communication	The results revealed that 85.5% (65/76) of the visit/sites demonstrated an absence of inflammation; 10.5% (8/76) of the visit/sites demonstrated slight redness; 1.3% (1/76) demonstrated peri-implant red and moist tissues; 2.6% (2/76) demonstrated granulation tissue associated with the implants; and 0% (0/76) demonstrated infection of the peri-implant soft tissues.	8957784
allergic inflammation	Altered Intercellular Communication	Therefore, adhesion molecule expression is thought to be important in the prolonging and pathogenesis of allergic inflammation.	8958658
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Specimens were sectioned horizontally and vertically and were examined for terminal and velluslike (miniaturized) hairs, follicular stelae, follicular units, and perifollicular inflammation and fibrosis.	8959948
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Significant degrees of inflammation and fibrosis were present in only 10% to 12% of cases of CTE and normal controls, but occurred in 37% of cases of AGA.	8959948
prostatitis	Altered Intercellular Communication	Prostate volume, histologically documented prostatic inflammation and history of urinary retention prior to PSA determination may partly explain the abnormal elevation of serum PSA in patients with BPH.	8961676
Inflammation	Altered Intercellular Communication	The inflammation is produced as the consequence of a non-specific response to several agents.	8963907
Inflammation, Spondylarthritis	Altered Intercellular Communication	Long-term evolution of gut inflammation in patients with spondyloarthropathy.	8964393
Spanish Language, Gastrointestinal inflammation, Spondylarthritis	Altered Intercellular Communication	Intestinal inflammation has been observed in patients with spondyloarthropathy (SpA).	8964393
Gastrointestinal inflammation	Altered Intercellular Communication	This prospective study reports the evolution of the intestinal inflammation observed in patients with SpA.	8964393
Inflammation	Altered Intercellular Communication	Articular remission rates were independent of initial gut inflammation and associated with endoscopic and histological remission.	8964393
Inflammation, Arthropathy	Altered Intercellular Communication	Persistent gut inflammation was observed in active joint disease.	8964393
Inflammation	Altered Intercellular Communication	Gut inflammation rarely disappeared, despite the persistence of articular complaints.	8964393
Inflammation, Spondylitis	Altered Intercellular Communication	Initial chronic gut inflammation implied a high risk of evolution to ankylosing spondylitis.	8964393
Inflammation, Diarrhea	Altered Intercellular Communication	Mainly patients with initial chronic inflammation and mild complaints of diarrhea were at risk.	8964393
Inflammatory Bowel Diseases, Inflammation, Diarrhea, Spondylitis	Altered Intercellular Communication	Presence of chronic gut inflammation and mild complaints of diarrhea implies a high risk of evolution to ankylosing spondylitis and IBD.	8964393
Inflammation, Neoplasms	Altered Intercellular Communication	The expression of peritumoral vascular somatostatin receptor and substance P receptor appears independent of receptor expression in the tumor, of tumor stage, and of the grade of local inflammation.	8964396
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Furthermore, some cytokines are considered to play a role in gastric mucosal inflammation.	8964399
Inflammation	Altered Intercellular Communication	All three cytokines are potent activators of the hypothalamic-pituitary-adrenal axis, through which they restrain inflammation, whereas IL-6 itself plays a role in the termination of inflammation as well.	8964868
Inflammation	Altered Intercellular Communication	However the combination of an artificial lense and silicone oil will lead to a strong inflammation in the anterior segment of the eye.	8965465
Communicable Diseases, Inflammation	Altered Intercellular Communication	After Gd-DTPA administration, granulation tissue surrounding the infection was enhanced in all cases and also the areas of vascularized inflammation within bone marrow were enhanced in two cases.	8966244
Inflammation, Tumoral calcinosis	Altered Intercellular Communication	We describe a case of diaphyseal inflammation in several bones with high levels of phosphorus in an 8-year-old boy who later developed subcutaneous masses of tumoral calcinosis.	8970054
Inflammation, Idiopathic Pulmonary Fibrosis, Blood Circulation, Sarcoidosis, Lung Diseases, Interstitial	Altered Intercellular Communication	In IPF and sarcoidosis, the release of the actual GRP gene products is increased in the lung and the bloodstream, and GRP may play a role during the processes of inflammation and remodeling in interstitial lung diseases.	8970357
Inflammation	Altered Intercellular Communication	Our finding that the CD40 antigen is present on only a minority of normal endothelial cells, whereas strong staining can be detected on the majority of endothelial cells in inflammatory processes, complements previous reports which suggest that this surface receptor plays an important role in tissue inflammation.	8971558
Inflammation	Altered Intercellular Communication	Ideal candidates were chosen from both previously operated and unoperated patients whose computed tomography (CT) scan findings could not differentiate benign mucosal thickening from active inflammation.	8972429
Inflammation, Osteitis, Acute infectious disease	Altered Intercellular Communication	Nuclear scintigraphy scans using indium (In-111), gallium (Ga-67), and technetium (Tch-99m) were used to differentiate acute infection from chronic inflammation involving bone (osteitis) and/or mucosa.	8972429
anti-endothelial cell antibody, Vasculitis, CTCAE, Vascular Diseases	Altered Intercellular Communication	AECA target as yet unidentified antigens on the endothelial cell surface and have been identified in patients with vasculitic disorders and inflammatory conditions with a vasculitic component.	8973622
Inflammation	Altered Intercellular Communication	Some of the bacterial virulence factors allowing mucosal colonization and inflammation have been described.	8975353
Inflammation, Bronchiolitis Obliterans, Fibrosis Assessment	Altered Intercellular Communication	A specimen of lung tissue was obtained by thoracoscopic biopsy, and histologic examination showed bronchiolitis obliterans, with bronchiolar narrowing or obliteration due to submucosal fibrosis and inflammation.	8976086
Keratitis, Abnormal corneal epithelium morphology, Maxillary Sinus Carcinoma	Altered Intercellular Communication	A 44-year-old man developed a corneal epithelial abnormality associated with conjunctival and corneal inflammation following radiation therapy for maxillary cancer.	8976704
Airway structure, ARCN1 gene, Asthma	Altered Intercellular Communication	Role of sputum differential cell count in detecting airway inflammation in patients with chronic bronchial asthma or COPD.	8977600
Airway structure, ARCN1 gene, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Sputum may provide an alternative source of bronchial cells to investigate characteristics of airway inflammation and its functional correlates in patients with asthma or chronic obstructive pulmonary disease (COPD).	8977600
Inflammation	Altered Intercellular Communication	Overall, with respect to endothelial adhesion events, our findings support an important role for VCAM-1 in sustaining chronic inflammation in cutaneous LE.	8977665
Inflammation, Sore to touch, Swelling, Pain Distress Question	Altered Intercellular Communication	Significant improvement in the joint complaints and inflammation parameters was observed including a decrease in the number of painful (-46%) and swollen (-45%) joints, tenderness (Ritchie Index: -50%) and degree of swelling (-46%), patient's assessment of pain (-35%), the duration of morning joint stiffness (-37%), as well as a decrease in C-reactive protein (-52%).	8977676
Onychomycosis, Glossitis	Altered Intercellular Communication	In two patients, Scopulariopsis infection produced a total dystrophic onychomycosis associated with painful periungual inflammation.	8977686
Lymphoma, T-Cell, Cutaneous, Inflammation, Exfoliative dermatitis	Altered Intercellular Communication	These studies show that S aureus containing superantigen enterotoxins are commonly found in patients with CTCL especially individuals with erythroderma where they could exacerbate and/or perpetuate stimulate chronic T-cell expansion and cutaneous inflammation.	8978274
Gastritis, Traumatic injury	Altered Intercellular Communication	The aim of this study was to define the association of vacA genotype with gastric inflammation and injury, in vitro cytotoxin activity, and peptic ulceration.	8978347
Inflammation, Duodenal Ulcer	Altered Intercellular Communication	H. pylori strains of vacA signal sequence type s1a are associated with enhanced gastric inflammation and duodenal ulceration.	8978347
Inflammation, Ulcer	Altered Intercellular Communication	vacA s2 strains are associated with less inflammation and lower ulcer prevalence.	8978347
Inflammation	Altered Intercellular Communication	Excessive enterogastric reflux following partial gastrectomy is believed to be responsible for the cause of inflammation in the gastric remnant.	8978806
Inflammation, Pituitary Gland	Altered Intercellular Communication	The patient underwent a transsphenoidal biopsy which revealed chronic inflammation in the hypophysis, mucosa of the sphenoid sinus, and dura mater.	8980889
Inflammation, Pituitary Gland	Altered Intercellular Communication	The chronic inflammation of the hypophysis and infundibulum is thought to have spread from the cavernous sinus.	8980889
Inflammation, Primary malignant neoplasm, Thrombosis	Altered Intercellular Communication	The membrane carbohydrate antigen, sialyl Lewis x (sLe(x)), is involved in cellular adhesive interactions in many diseases, such as cancer, inflammation and thrombosis.	8981096
Inflammation, Psoriasis	Altered Intercellular Communication	Psoriasis is characterized by abnormal cell proliferation, inflammation and increased biosynthesis of various cytokines.	8982405
Necrotizing granulomatous inflammation	Altered Intercellular Communication	During surgery, an intestinal granulomatous inflammation was observed adhered to the hernial sac.	8984586
Inflammation	Altered Intercellular Communication	Bronchial biopsy specimens were obtained from 16 patients, seven controls without signs of inflammation and nine patients with severe inflammatory processes in the epithelium.	8984703
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histology showed inflammation in 88% of the biopsies and signs of fibrosis in 24%.	8985291
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Mean ALT values correlated with inflammation but not with fibrosis in the biopsies.	8985291
Muscle damage, Inflammation, Toxic effect	Altered Intercellular Communication	We determined whether laboratory tests for muscle damage and inflammation could predict impending limb toxicity.	8985522
Cataract, Intraocular inflammation	Altered Intercellular Communication	Management of intralenticular metallic foreign bodies may be conservative till intraocular inflammation or cataract develops.	8985549
Inflammation, Pterygia	Altered Intercellular Communication	In our case, both processes occur and are presumed to result from excessive ultraviolet radiation, wind and chlorine exposure, and perhaps, chronic inflammation; features that have been ascribed to the pathogenesis of pingueculae and pterygia.	8985643
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	Serum level of VCAM-1 can be an useful marker of ocular inflammation in the evaluation of uveitis.	8986245
Inflammation	Altered Intercellular Communication	PAF antagonists appeared to reduce significantly the local peritoneal consequences of local inflammation.	8986985
Inflammation, Perforation of nasal septum	Altered Intercellular Communication	When the nasal passages of platers were examined 17% had inflammation and 14% had septal perforation.	8987377
Cataract, Optic Atrophy, Atrophic	Altered Intercellular Communication	The most frequently associated ocular pathologic features were optic atrophy (96.4%), atrophy of the inner retina (85.7%), cataract (64.3%), and inflammatory conditions (50%).	8988428
Hypertrophic Cardiomyopathy	Altered Intercellular Communication	Our results give evidence that parathyroid hormone per se plays an important role in the maintainance of myocardial hypertrophy.	8989242
Inflammation, Chronic pain	Altered Intercellular Communication	It can result in disability and lost time from work because of chronic pain, inflammation, and/or ulceration.	8989968
Inflammation, Aneurysm, Hepatobiliary Disorder, Traumatic injury, Hypertension, CTCAE	Altered Intercellular Communication	Secondary aneurysms are thought to be due to liver disease, portal hypertension, trauma, or inflammation.	8989976
Doctor of Chiropractic, Dilated Cardiomyopathy Pathway, Myocardial, Myocarditis	Altered Intercellular Communication	A proportion of patients with dilated cardiomyopathy (DCM) may have ongoing myocardial damage secondary to viral or immune mediated myocardial inflammation.	8994739
Osteomyelitis, Communicable Diseases, RECIL MR	Altered Intercellular Communication	Nonpyogenic inflammations and neuroarthropathic joints were indistinguishable from infection by MR.	8995457
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	In 22 (88%) of these, the cytological diagnosis was granulomatous inflammation suggestive of sarcoidosis.	8995462
Inflammation	Altered Intercellular Communication	It is a potent mediator of inflammatory response and is thought to play a major role in recruiting monocytes into the site of inflammation.	8995729
Inflammation, Diarrhea, Epithelial, Colitis	Altered Intercellular Communication	Collagenous colitis is a chronic diarrheal disease characterized by a normal or near-normal mucosa endoscopically and microscopic inflammation in the lamina propria, surface epithelial injury and a thick subepithelial collagen layer.	8995938
Epithelial Damage, Inflammation	Altered Intercellular Communication	Biopsy specimens were reviewed by two pathologists for degree of collagen layer thickness, epithelial damage, and inflammation.	8995938
Epithelial Damage, Inflammation, Metaplasia	Altered Intercellular Communication	There was no significant difference in collagen thickness, epithelial damage, and inflammation between the two groups, but Paneth cell metaplasia was seen more often in those with ongoing symptoms.	8995938
HIV Infections, Bronchitis	Altered Intercellular Communication	HIV disease is frequently complicated by episodic acute bronchitis, suggesting the presence of chronic bronchial inflammation.	8996005
Hypernatremia	Altered Intercellular Communication	The adaptation of the left ventricle to chronic pressure overload is a complex process of hormonal, structural and hemodynamic factors.	8996312
Inflammation, Endarteritis	Altered Intercellular Communication	Findings in our patient strongly suggest that a secondary inflammation reaction caused by the destruction of the cysts might have enhanced the process of endarteritis.	8996514
Inflammation, SLC25A10 gene	Altered Intercellular Communication	These data suggest that studies of platelets are more useful in the diagnosis of DIC at early stages of impaired organ function than are other indicators of inflammation such as the level of C-reactive protein.	8997105
Inflammation	Altered Intercellular Communication	It was diagnosed as the inflammation originated in the sphenoid and ethmoid sinuses, which extended to the cavernous sinus and then involved III, IV, and VI cranial nerves.	8997145
Perinephritis	Altered Intercellular Communication	CT demonstrated perinephric inflammation extending to the colon, complex air-fluid collections within the kidney, or extension of renal contrast into the colon.	9000366
Inflammation, Edema	Altered Intercellular Communication	Histologically, peritumoral stroma showed inflammation or edema in two patients, whereas no histological abnormality was found in the other patients.	9000368
Inflammation, Neoplasms	Altered Intercellular Communication	TRUS sometimes overstaged perirectal growth of tumour in 7 patients, due to inflammation (5 patients) or incorrect positioning of the balloon in relation to the tumour surface (2 patients).	9000390
Inflammation, Cholelithiasis, Gallbladder Carcinoma	Altered Intercellular Communication	Gallstone disease and cholelithiasis-associated chronic biliary inflammation may play a causative role in the pathogenesis of gallbladder carcinoma.	9001552
Parkinsonian Disorders	Altered Intercellular Communication	These results do not confirm the changes in neurotransmitter concentrations predicted according to the model, although we cannot rule out that the predicted changes might have been observed if the Parkinsonian group had been further subdivided into groups diagnosed on the basis of the patients' clinical picture (akinetic-rigid, tremor-dominant, equivalent type) and compared with the control group.	9001716
Inflammation, Hypopyon	Altered Intercellular Communication	Postoperative inflammation was present in all eyes, and a small hypopyon developed in 28% of the eyes.	9002129
Inflammation, Chronic sinusitis	Altered Intercellular Communication	The mucociliary clearance of the maxillary sinus disturbed by chronic inflammation was restored by ESS, indicating the clinical effectiveness of ESS for the treatment of chronic sinusitis.	9003210
Cataract, Intraocular inflammation, Joint Subluxations	Altered Intercellular Communication	Associated clinical findings included signs of intraocular inflammation in all patients, secondary cataract in eight (89%), and subluxation of the lens in six (67%).	9003334
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Granulomatous orbital inflammation may occur as an isolated condition of unknown origin.	9003349
Sarcoidosis, Orbital Pseudotumor	Altered Intercellular Communication	The records of all patients with diagnosis of orbital pseudotumor and orbital sarcoidosis from the Orbital Center Amsterdam in the period between 1976 and 1994 were reviewed to define those with idiopathic granulomatous orbital inflammation.	9003349
Orbital Pseudotumor	Altered Intercellular Communication	The authors studied the clinicotherapeutic aspects and histopathology of idiopathic granulomatous orbital inflammation by analysis of their own series and the literature.	9003349
Orbital Pseudotumor	Altered Intercellular Communication	Their study group encompassed seven patients with idiopathic granulomatous orbital inflammation.	9003349
Necrotizing granulomatous inflammation, Granulomatous inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histopathologic analysis showed a spectrum of granulomatous inflammation, admixed with nongranulomatous inflammation and fibrosis.	9003349
Sarcoidosis, Orbital Pseudotumor	Altered Intercellular Communication	Based on this study and the literature, it appears that idiopathic granulomatous orbital inflammation is more related to orbital pseudotumor than to orbital sarcoidosis.	9003349
Ulcerative Colitis	Altered Intercellular Communication	Biopsy samples of mucosa were taken during colonoscopy from the proximal colon and rectum of 12 patients, six with ulcerative colitis (UC) and six with non-inflammatory conditions.	9003751
Inflammation, Traumatic injury	Altered Intercellular Communication	Intraocular surgery, trauma and inflammation may lead to intraocular accumulation of fibrin.	9004880
Conjunctivitis	Altered Intercellular Communication	Once recognized, conjunctival inflammation often takes several weeks to resolve.	9006422
Inflammation, Meningitis, Bacterial	Altered Intercellular Communication	Although cerebrovascular involvement in the acute phase of inflammation may be particularly important for the still unacceptably high morbidity and mortality, only, a few studies have investigated cerebrovascular changes in bacterial meningitis.	9007746
Inflammation	Altered Intercellular Communication	Definition of different patterns of inflammation in GCA might, therefore, facilitate the design of differentiated therapeutic approaches.	9008596
Barrett Esophagus, Hiatal Hernia, Gastro-esophageal reflux disease with esophagitis, Esophagitis	Altered Intercellular Communication	Reflux esophagitis was diagnosed in 118 patients, hiatal hernia without esophageal inflammation in 109, and Barrett's esophagus in 13.	9009123
Tissue damage, Inflammation, Electrocardiogram: myocardial infarction (finding), Necrosis	Altered Intercellular Communication	Tissue damage, inflammation and necrosis are hallmarks of myocardial infarction.	9009477
Tissue damage, Inflammation, Rheumatic Heart Disease	Altered Intercellular Communication	On the other hand chronic rheumatic heart disease encompass certain amount of acute phase status in terms of tissue damage and inflammation does exist unaccompanied by altered systemic homeostasis and haemostasis.	9009477
Subacute, Peripheral demyelinating neuropathy	Altered Intercellular Communication	Three other patients developed a subacutely progressive, functionally disabling, demyelinating neuropathy; sural nerve biopsy in two patients showed lymphocytic inflammation.	9010008
Chronic lymphocytic inflammation	Altered Intercellular Communication	Perivascular or vasculitic lymphocytic inflammation was detected in all specimens.	9010017
Rheumatoid Arthritis, Inflammation, Joints	Altered Intercellular Communication	Clinical improvement and radiological deterioration in rheumatoid arthritis: evidence that the pathogenesis of synovial inflammation and articular erosion may differ.	9010054
Refractory anemias, Inflammation, Joints	Altered Intercellular Communication	Articular erosion continues in RA despite clinical improvement and is accelerated in those with evidence of continuing synovial inflammation, reflected in clinical and laboratory measures of disease activity.	9010054
Refractory anemias, Inflammation, Joints	Altered Intercellular Communication	Since many therapies in RA suppress inflammation, but not erosion, these findings suggest that the pathogenesis of articular erosion may differ from that of synovial inflammation.	9010054
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To evaluate the impact of chronic inflammation on lipoprotein lipase (LPL) levels and tri-glyceride metabolism in patients wit rheumatoid arthritis (RA).	9010384
Inflammation	Altered Intercellular Communication	The complex of immune and morphological changes, developing chronic inflammation underlying chronic course of disease, have been detected by clinical trials.	9011656
Gastric Ulcer, CTCAE 5, Inflammation, Perforation of gallbladder, Perforation (observation)	Altered Intercellular Communication	The author presents the case of a double perforation of a gastric ulcer combined with perforation of the gallbladder altered by inflammation.	9011953
Inflammation	Altered Intercellular Communication	During inflammation, the amount of low-density lipoprotein (LDL) in the inflamed joint is increased.	9013133
Inflammation, Herpes zoster disease	Altered Intercellular Communication	The possible involvement of mast cell proteases in the cutaneous inflammation of herpes zoster was studied histochemically in ten patients.	9014866
Inflammation, Herpes zoster disease	Altered Intercellular Communication	These results show prominent alterations in mast cell proteinases and protease inhibitors, indicating that these enzymes participate in the cutaneous inflammation due to herpes zoster.	9014866
Inflammation, Spinal Cord Injuries, Stanford Cancer Institute, Ulcer	Altered Intercellular Communication	To measure circulating levels of well-studied, easily quantifiable surrogate markers or mediators of inflammation and tissue remodeling in patients with spinal cord injury (SCI) suffering from pressure ulcers.	9014956
Appendicitis, CTCAE	Altered Intercellular Communication	The presence of an appendicolith was considered a secondary finding as was isolated periappendiceal inflammation; however, appendicitis was not diagnosed in such patients unless an enlarged appendix was definitely identified.	9016216
Airway structure	Altered Intercellular Communication	Sputum analysis is a useful technique for the study of airway inflammation.	9016474
Inflammation	Altered Intercellular Communication	Mild villous shortening and mild inflammation of the lamina propria were observed in duodenal mucosa in 18 subjects (3.7%).	9018766
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	Salivary gland tissue in HCV patients responds to damage in a fashion similar to primary Sjogren's syndrome, the only difference being a lesser degree of inflammation.	9023556
Inflammation	Altered Intercellular Communication	Concentrations of serum amyloid A protein (SAA), one of the acute phase proteins, were also measured as an indicator of inflammation.	9026271
Airway structure, Asthma	Altered Intercellular Communication	Comparison between hypertonic and isotonic saline-induced sputum in the evaluation of airway inflammation in subjects with moderate asthma.	9027440
Airway structure, Asthma	Altered Intercellular Communication	Hypertonic saline-induced sputum has recently been used for the evaluation of airway inflammation in asthma.	9027440
Airway structure, Asthma, Bronchial Hyperreactivity	Altered Intercellular Communication	We compared the inflammatory cell composition of hypertonic saline-induced sputum with that of isotonic saline-induced sputum in 21 asthmatic subjects and, at baseline and 30 min after each sputum induction, we measured bronchial hyper-responsiveness to methacholine as an indirect marker to detect increased airway inflammation.	9027440
Inflammation	Altered Intercellular Communication	This fact must be considered in the evaluation of soluble markers of inflammation in hypertonic saline-induced sputum.	9027440
Inflammation	Altered Intercellular Communication	All of the specimens contained acid-fast bacilli (AFB) and exhibited features of chronic inflammation.	9030109
Inflammation, Pterygium Of Conjunctiva And Cornea, Lagophthalmos, Leprosy	Altered Intercellular Communication	In the etio-pathogenesis of the pterygium that occurs in leprosy patients, the chronic inflammation that is a feature of the disease, the involvement of the nerves within the pterygium, the increased exposure to sunlight, dust and wind (especially in patients having lagophthalmos), and the ostrasization by society that necessitates living predominantly outdoor lives, should be taken into account.	9030109
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation is present in asthma and is thought to play a significant part in the development of airflow obstruction.	9032177
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	In chronic obstructive pulmonary disease (COPD), neutrophilic inflammation is present in the airway lumen, whereas the submucosa displays a lymphocytic infiltrate.	9032177
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	Less is known about the nature and mechanisms of inflammation in COPD than in asthma.	9032177
Inflammation, Neoplasms, Unicameral bone cyst	Altered Intercellular Communication	Indications for operation were tumours, large dental-type cysts, traumatic bone loss and chronic inflammation in sinuses which had been previously operated on.	9032598
Inflammatory abnormality of the eye	Altered Intercellular Communication	Our results demonstrate the potential involvement of MMPs and their modulation by cytokines produced by infiltrating inflammatory cells in destructive ocular inflammation.	9033278
Cataract, Inflammation	Altered Intercellular Communication	[Efficacy and tolerability of a combination of indomethacin and gentamicin for preventing inflammation after cataract surgery].	9033890
Inflammatory abnormality of the eye	Altered Intercellular Communication	Post-operative ocular inflammation was assessed clinically on the 1st, 7th, 15th and 30th post-operative days.	9033890
Cataract, Inflammation	Altered Intercellular Communication	Eye drops combining 0.1% indomethacin and gentamicin proved to be effective and well tolerated in preventing inflammation after cataract surgery.	9033890
Inflammation, Sample Size Calculation	Altered Intercellular Communication	We suggest that IL-4, IL-10, and IL-13 may be some of the cytokines that contribute to the disease process, and that IL-13 may be a serologic indicator of systemic inflammation in patients with SSc.	9034992
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Analysis of synovial tissue revealed a low, mild, and moderate degree of inflammation for joints with normal, degenerated, and OA cartilage, respectively.	9034997
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Synovial membrane inflammation and cytokine production in patients with early osteoarthritis.	9034998
Degenerative polyarthritis, Inflammation, Damage, Knee pain	Altered Intercellular Communication	To establish the presence of inflammation in and cytokine production by synovial membranes from patients with various stages of early osteoarthritis (OA), with knee pain, normal knee radiographs, and arthroscopic evidence of chondral damage.	9034998
Inflammation, Fibrosis Assessment, Colitis, Ischemic	Altered Intercellular Communication	The pathological study showed an ischemic colitis with extensive longitudinal ulcers in the antimesenteric border, presence of granulation tissue with inflammation and transmural fibrosis.	9035512
Inflammation, Squamous cell carcinoma	Altered Intercellular Communication	In one case a squamous cell carcinoma developed at the site of inflammation.	9036139
Inflammation, Pyelonephritis	Altered Intercellular Communication	Interference current proved beneficial in chronic pyelonephritis patients with latent inflammation.	9036659
Inflammation, Gastritis	Altered Intercellular Communication	However the presence of gastritis, irrespective of the severity of inflammation or activity had no influence on ODC activity.	9038661
Inflammation	Altered Intercellular Communication	These results indicate that the histological changes associated with longstanding H pylori infection rather than inflammation alone are associated with increased polyamine biosynthetic activity.	9038661
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Type I collagen mRNA was more strongly expressed in patients than in controls and correlated with the degree of fibrosis, but not with any of the necro-inflammatory lesions (portal inflammation, piecemeal necrosis, and lobular necrosis).	9038738
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Noninvasive leukocyte scintigraphy for assessment of localization, extent, and degree of active inflammation in acute colonic inflammatory bowel disease have been shown to correlate well with endoscopy.	9040207
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In seven patients, the extent assessments almost matched (+/- one segment), and in the remaining three patients (two UC, one CD) the scan grossly misinterpreted active histological inflammation (> or = +/- two segments).	9040207
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In patients with UC, the sensitivity, specificity, and diagnostic accuracy concerning the extent of inflammation were 0.84, 0.79, and 0.83, respectively.	9040207
Inflammation, Lymphangitis	Altered Intercellular Communication	A 78-year-old woman with a silicone implant in her first carpometacarpal joint had acute inflammation and lymphangitis beginning 24 hours after a dental root canal procedure.	9040890
Inflammation, Hyperplasia	Altered Intercellular Communication	There were no histologic changes seen at the tattoo sites in 48 patients, mild chronic inflammation in 6 patients, and hyperplastic change in 1 patient.	9041001
Renal glomerular disease	Altered Intercellular Communication	Membrane attack complex and membrane cofactor protein are related to tubulointerstitial inflammation in various human glomerulopathies.	9041539
Inflammation	Altered Intercellular Communication	The pathology of pericardium revealed chronic inflammation only.	9041774
Refractory anemias, Inflammation, Synovitis	Altered Intercellular Communication	The findings presented here are consistent with the concept that early RA is the result of a synovitis process of longer duration and that macrophage-derived cytokines play an important role in maintaining the clinical signs of inflammation.	9041933
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation in asthma consists of variably increased numbers of mononuclear and polymorphonuclear cells, and there is a growing body of evidence to suggest a primary role for lymphocytes and eosinophils in the pathogenesis of asthma.	9042623
Inflammation, Retinitis Pigmentosa, polychondritis	Altered Intercellular Communication	Relapsing polychondritis (RP) is an uncommon disorder of unknown aetiology characterized by inflammation and destruction of the cartilaginous structures of many organs, including the tracheobronchial tree.	9042655
Tracheal Stenosis, Malignant Neoplasms	Altered Intercellular Communication	They were hospitalized in our Department due to acute and chronic inflammations of respiratory tract, malignant tumours and larynx, and trachea stenosis.	9045148
Communicable Diseases	Altered Intercellular Communication	The pathogenesis of neurological manifestations with EBV infection consists of primary inflammations of EBV infection, and secondary immunologic reactions.	9046853
Communicable Diseases, Neurologic Symptoms	Altered Intercellular Communication	Clinical course and CSF findings revealed that his fulminant neurological symptoms were most likely produced by the secondary immunologic reactions following the primary inflammations by EBV infection.	9046853
Inflammation, OSTF1 gene, Fibrosis Assessment, Chronic disease	Altered Intercellular Communication	Oral submucous fibrosis (OSF) is a chronic disease of the oral cavity characterized by inflammation and progressive mucosal fibrosis.	9049906
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	One eye with preoperative glaucoma developed absolute glaucoma with resolution of inflammation.	9051508
Inflammation	Altered Intercellular Communication	Lee's and Ritchie's indices and radiographic alterations were more severe in the nodular group, whereas tests for inflammation were not significantly different.	9051854
Rheumatoid Arthritis, Neurogenic Inflammation	Altered Intercellular Communication	Serum substance P was assayed in rheumatoid arthritis patients and healthy controls to evaluate whether neurogenic inflammation with substance P release is significant in rheumatoid arthritis.	9051855
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Mean serum substance P level was significantly higher in rheumatoid arthritis patients than in controls and was not correlated with disease duration, morning stiffness duration, Thompson's articular index, Larsen's radiographic score, or the following laboratory indices of inflammation: erythrocyte sedimentation rate, C-reactive protein, and alpha 1-acid glycoprotein.	9051855
Rheumatoid Arthritis, Neurogenic Inflammation	Altered Intercellular Communication	Neurogenic inflammation with substance P release may contribute significantly to the pathogenesis of rheumatoid arthritis.	9051855
Inflammation, Neurogenic Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The absence of correlations between serum substance P and clinical or laboratory indices of inflammation may reflect complex interactions between neurogenic inflammation and other pathogenic mechanisms, which may influence clinical features and laboratory tests in rheumatoid arthritis patients.	9051855
Sjogrens Syndrome", Gastritis	Altered Intercellular Communication	Gastric inflammation, in either the corpus or antrum, was found in 85% of patients with Sjogren's syndrome and in 61% of control subjects (P = 0.02).	9051869
Sjogrens Syndrome", Gastritis	Altered Intercellular Communication	Compared with control subjects, gastric inflammation was seen more often in patients with Sjogren's syndrome.	9051869
Inflammation, gastrointestinal toxicity	Altered Intercellular Communication	Inhibition of constitutively expressed cyclooxygenase (Cox-1) is thought to play an important role in the gastrointestinal toxicity of nonsteroidal anti-inflammatory drugs (NSAID), while their therapeutic action may be due to inhibition of the enzyme Cox-2, which is specifically expressed at sites of inflammation.	9051872
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	[99mTC]HMPAO leukocyte scintigraphy is superior to the activity index and the gastroenterologists' clinical assessment of active inflammation in IBD patients.	9052524
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Scintigraphy allows assessment of the existence, extent, and intensity of active inflammation in IBD patients in one examination with high accuracy.	9052524
Granulomatous inflammation	Altered Intercellular Communication	The excised mass consisted of granulomatous inflammation with numerous osteoclast-like giant cells and scattered atypical Touton giant cells.	9054486
Intraocular inflammation, Juvenile Xanthogranuloma, Hyphema	Altered Intercellular Communication	Juvenile xanthogranuloma (XG) of the iris can occur as a large solitary mass, without signs of intraocular inflammation or hyphema.	9054486
Inflammation	Altered Intercellular Communication	Evaluation of knee joint inflammation before and after intra-articular glucocorticoid treatment.	9057801
Inflammation, Lyme Arthritis	Altered Intercellular Communication	Seven patients with arthritic disease and with clinical signs of inflammation of the knee joint, were investigated with positron emission tomography (PET) after injection of [N-methyl-11C]-D-deprenyl.	9057801
Inflammation, Tissue injury	Altered Intercellular Communication	C-reactive protein (CRP) is the classical acute-phase protein most recognized as an early marker in diseases characterized by inflammation and tissue injury.	9060080
Inflammation, Bone necrosis, Hemosiderosis	Altered Intercellular Communication	Pathologically in both patients, osteoarthrotic changes with small foci of bone necrosis and nonspecific inflammation and moderate amount of hemosiderosis in the synovium were observed.	9060499
Inflammation	Altered Intercellular Communication	Only ClearSite induced significant changes in IL-8 and bFGF levels when untreated scars were compared with posttreatment lesions, suggesting that the hydrogel augments collagenolysis via promotion of inflammation.	9063511
Inflammation, Dermatitis, Atopic, Data types - Address	Altered Intercellular Communication	In order to elucidate the role of the soluble forms in skin inflammation, we determined the serum levels of E-selectin, vascular cell adhesion molecule-1 (VCAM-1), and intercellular adhesion molecule-1 (ICAM-1) in patients with atopic dermatitis (AD).	9065702
Airway structure, Allergic asthma, Airway Obstruction	Altered Intercellular Communication	Reversible airway obstruction and airway inflammation following allergen exposure represent crucial pathophysiological features of allergic asthma.	9066510
Asthma, allergic inflammation	Altered Intercellular Communication	Therefore, we evaluated the applicability of allergen-specific conjunctival challenge (ASCC) in adults with asthma to define the diagnosis of specific sensitization and the grade of specific sensitization, and to detect the presence of allergic inflammation.	9066510
allergic inflammation	Altered Intercellular Communication	As recently described, conjunctival challenge represents an easy diagnostic tool in allergic inflammation.	9066510
Inflammation, Verrucous carcinoma	Altered Intercellular Communication	The pathogenesis of verrucous carcinoma, including chronic inflammation and human papillomavirus, is also discussed.	9066754
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Poorly differentiated lesions were significantly larger than intermediately and well differentiated lesions (P = 0.03 and P = 0.01, respectively) and were significantly associated with the presence of extensive necrosis, marked periductal inflammation and periductal fibrosis (P < 0.0001).	9067733
Tumor necrosis	Altered Intercellular Communication	Overexuberant production of tumour necrosis factor-alpha (TNF-alpha) by macrophages and other cells is thought to contribute to the development of permanent lung damage in many inflammatory conditions.	9068814
Inflammation	Altered Intercellular Communication	Recent evidence suggests a role for inflammation in this process.	9070552
Inflammation	Altered Intercellular Communication	Leukocyte-endothelial cell interactions are important in inflammation and are regulated by cell adhesion molecules.	9070552
Communicable Diseases, Hypersensitivity, Aspergillus, Pulmonary Aspergillosis	Altered Intercellular Communication	The entity of allergic pulmonary aspergillosis includes various diseases of the lung which are caused by not only allergic reactions to aspergillus but also destructive inflammations due to saprophytic infection of aspergillus in lower respiratory tracts.	9071092
Eosinophilic disorder, Inflammation, Pneumonia	Altered Intercellular Communication	All cases had hard or firm mucous plugs in the proximal bronchi, peripheral to which we found inflammation with tissue eosinophilia (bronchocentric granulomatosis with tissue eosinophilia : 5 cases, xanthogranuloma-like lesions : 2 cases, eosinophilic pneumonia : 2 cases and organizing pneumonia : 4 cases).	9071094
Crohn Disease, Pyelonephritis, Interstitial inflammation, Nephritis	Altered Intercellular Communication	Interstitial inflammation was present in 19 cases: chronic pyelonephritis (2 patients), focal nephritis (5 patients), multiple cortical abscesses (7 patients), granulomatous nephritis (5 patients).	9071721
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	ELOCA enabled quantitation of multiple mRNAs in small mucosal biopsies from untreated patients with CIIBD and supported a role for IL-8 and iNOS in acute inflammation in both UC and CD.	9072008
Primary sclerosing cholangitis, Inflammation, Bile Ducts, Extrahepatic	Altered Intercellular Communication	Primary sclerosing cholangitis is characterized by progressive fibrotic inflammation and obliteration of intra- and extrahepatic bile ducts.	9075663
Cardiovascular Diseases	Altered Intercellular Communication	Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men.	9077376
Inflammation, Thrombosis	Altered Intercellular Communication	Inflammation may be important in the pathogenesis of atherothrombosis.	9077376
Aneurysmal, Inflammation, Aortic Aneurysm, Abdominal, Atherosclerosis	Altered Intercellular Communication	Abdominal aortic aneurysms are frequently associated with atherosclerosis, and inflammation may actually be an important factor in aneurysmal dilatation.	9081131
Inflammation, Aortic Aneurysm	Altered Intercellular Communication	Hence it could be assumed that C. pneumoniae may play a role in maintaining an inflammation and triggering the development of aortic aneurysms.	9081131
Refractory anemias, Inflammation	Altered Intercellular Communication	Histologic and immunohistochemical examinations added useful information to arthroscopy and showed similarly high frequencies of synovial inflammation in GOA and RA patients, differing clearly from those in the reference material.	9081245
Autoimmune Diseases, Inflammation, Retinal Degeneration	Altered Intercellular Communication	Systemic viral or bacterial inflammation as well as autoimmune disorders may present as phenocopies of hereditary retinal degenerations.	9081524
Juvenile rheumatoid arthritis, Uveitis	Altered Intercellular Communication	In one child, suffering from uveitis in combination with juvenile rheumatoid arthritis, a complete reduction of intraocular inflammation was achieved.	9081536
Brain Injuries	Altered Intercellular Communication	Different biogenic amine neurotransmitter responses to right and left hemisphere brain injury may underlie this mood asymmetry.	9081550
Infection	Altered Intercellular Communication	In case necrotizing inflammations of the oral cavity area were to be found infections due to anaerobic bacteria should be considered mostly occurring as mixed infections.	9081954
Necrosis with inflammation	Altered Intercellular Communication	They found out the necessity of an early diagnosis increases the possibilities of success upon this dangerous necrotic inflammation, because it has, nowadays, a high death-rate.	9082221
Arthralgia, Inflammation	Altered Intercellular Communication	Both treatments induced a significant decline in severity of arthralgia, in the number of joints with inflammation, in the level of C-reactive protein and in ESR.	9082588
Inflammation, Tonsillitis	Altered Intercellular Communication	The results indicate that chronic tonsillitis in the adult should be considered as such (higher expression of antigens associated with the chronic stages (p = 0.039), low and even lower expression of those associated with the intermediate and acute stages, respectively), whereas tonsillitis in children could perhaps be more correctly regarded as an expression of recurrent inflammation (higher expression of antigens associated with the acute stages (p = 0.022)).	9082752
Inflammation	Altered Intercellular Communication	Histological findings of mucosal inflammation were observed and H. pylori was isolated from the gastric mucosa.	9083755
Inflammation	Altered Intercellular Communication	Inflammation (both acute and chronic) improved in patients treated with lansoprazole plus amoxycillin.	9083908
Chronic infectious disease, Neutrophil migration, function	Altered Intercellular Communication	These results indicate that RXM decreases uterine endometrial cavity inflammation through reduction of neutrophil migration in inflammatory sites and is effective in treating chronic intrauterine infection.	9084925
Hyperparathyroidism	Altered Intercellular Communication	Lithium-associated hyperparathyroidism may be due to dysregulation of the caliostat, a feedback loop that subordinates parathyroid hormone secretion to serum calcium levels.	9085449
Orbital Pseudotumor	Altered Intercellular Communication	The degree of orbital inflammation was classified according to the clinical activity score of Mourits.	9086565
allergic inflammation	Altered Intercellular Communication	Eosinophil cationic protein (ECP) is one of the major, cytotoxic molecules produced by eosinophils, which can be used as a marker of allergic inflammation.	9088653
Cataract, Inflammation	Altered Intercellular Communication	Cataract surgery leads to a more or less intensive postoperative inflammation due to breakdown of the blood-aqueous barrier.	9091708
Necrotizing granulomatous inflammation	Altered Intercellular Communication	The differential diagnosis includes other granulomatous ocular inflammations.	9091716
Inflammation, Paraneoplastic Opsoclonus Ataxia	Altered Intercellular Communication	Even though paraneoplastic opsoclonus may be associated with an immunological response, there was no elevation of blood parameters associated with inflammation.	9092159
Edema of eyelid, Phlegmon	Altered Intercellular Communication	Inflammation of the orbital soft tissues presented as eyelid and orbital fat edema in 66 patients, as retrobulbar abscess in 11 and phlegmon in 10 patients.	9092187
Pneumonitis	Altered Intercellular Communication	Thus, meconium aspiration resulted in a biphasic pulmonary pressor response and severe pulmonary inflammation.	9094729
Squamous cell carcinoma of esophagus, Malignant Neoplasms	Altered Intercellular Communication	The high prevalence of HPV in COM-associated MESCC therefore provides a good model to explain the pathogenesis of chronic-inflammation-related human malignancies.	9094989
Single organ dysfunction, Inflammation, Cessation of life	Altered Intercellular Communication	The objective of this study was to evaluate the correlation between the early activation of inflammation and the rate of organ failure and death.	9095112
Urethritis	Altered Intercellular Communication	Acute urinary retention secondary to urethral inflammation from a vaginal contraceptive suppository in a 17-year-old boy.	9096278
Inflammation	Altered Intercellular Communication	Flexible cystourethroscopy revealed gross mucosal erythema and inflammation in the distal urethra and navicular fossa.	9096278
Calcified (qualifier), Inflammation	Altered Intercellular Communication	His brain computed tomography (CT) revealed marked calcifications of the basal ganglia, and pelvis magnetic resonance imaging (MRI) showed inflammation of his seminal vesicle.	9099593
Inflammation, Synovitis	Altered Intercellular Communication	in synovitis, might result in T cell accumulation and perpetuation of inflammation.	9099931
Inflammatory Bowel Diseases, Inflammation, Tissue injury	Altered Intercellular Communication	Increased numbers of gamma delta T cells localized in areas of inflammation and tissue injury were found in the majority of patients, irrespective of the type of IBD present.	9100225
Inflammation, Herpes zoster disease	Altered Intercellular Communication	This is the first report of brachial plexus inflammation associated with clinical herpes zoster paresis.	9101105
Inflammation	Altered Intercellular Communication	We suggest, the brachial plexus inflammation was a distal extension of a dorsal ganglionitis.	9101105
Inflammation, Humor	Altered Intercellular Communication	Postoperatively, a good wound seal was achieved with no leakage of aqueous humor from the anterior chamber, nor any inflammation.	9101577
Inflammation, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating, MS gene	Altered Intercellular Communication	The most intriguing finding is the detection of locally produced CSF oligoclonal IgG which may suggest the associated inflammation within the central nervous system in a number of patients with CIDP, and furthermore a pathogenic link between CIDP and multiple sclerosis.	9102806
Bronchial brand of guaifenesin-theophylline, Inflammation, Pharyngeal Stenosis, CTCAE, Congenital Abnormality, Trachea and Bronchus, Respiratory Failure	Altered Intercellular Communication	Her respiratory failure was due to pharyngial stenosis, deformity and inflammation of a trachea and lobar bronchus, and bronchial collapse.	9105165
Inflammation, Demographics Domain, Atherosclerosis, Diabetes Mellitus	Altered Intercellular Communication	To evaluate the role of both oxidation and inflammation in atherosclerosis, we compared LDL oxidizability, in vivo lipid and cholesterol oxidation, and basal and lipopolysaccharide (LPS)-stimulated production of various cytokines in normolipidemic patients with diabetes mellitus (DM: n = 11), cigarettes smokers (n = 14).	9105558
Inflammation	Altered Intercellular Communication	Results suggest increased in vivo oxidative stress and inflammation in DM and smoking, which is partly overcome by vitamin E.	9105558
Inflammation, Carcinoma, Carcinoid Tumor, Neoplasms, Granulomatosis, Fibrosis Assessment	Altered Intercellular Communication	Thirty patients (37.5%) had unsuspected findings such as interstitial fibrosis, noncaseating granulomatosis, chronic inflammation, and unsuspected neoplasia (three carcinomas, one carcinoid).	9106573
Inflammation, Angina, Unstable	Altered Intercellular Communication	Recent studies suggest a role for inflammation in the pathophysiology of unstable angina.	9107167
Chronic heart failure	Altered Intercellular Communication	Clinical research in chronic heart failure has recently focused on the stimulated neuro-hormonal compensatory mechanisms that could contribute to auto-aggravation of the disease.	9107560
Vasculitic neuropathy, Inflammation	Altered Intercellular Communication	Vasculitic neuropathy was demonstrated in only two patients, but nonspecific epineurial inflammation was present in 70% of nerve biopsies.	9109867
Inflammation, Temporomandibular Joint, Joint derangement, effusion	Altered Intercellular Communication	One hundred sixty-four TMJ patients were evaluated for internal derangement, effusion and inflammation, utilizing T1 and T2 weighted images.	9110615
Inflammation, Temporomandibular Joint, Edema, Congenital Abnormality	Altered Intercellular Communication	A high percentage of the TMJ patients demonstrated abnormal findings: disk displacement with reduction (DDR), 118/164 (72%); disk displacement without reduction (DDNR), 25/164 (15%); effusion, 113/164 (69%); inflammation or edema, 84/164 (51%); total TMJ abnormalities, 156/164 (95%).	9110615
Low Vision, Inflammation, Eye pain, No ocular symptoms, Scleritis, Exophthalmos	Altered Intercellular Communication	The main ocular symptoms were decreased vision, redness, and ocular and facial pain, whereas the main signs were proptosis, scleritis, and lid inflammation.	9111264
Inflammation, Necrosis	Altered Intercellular Communication	Orbital biopsy specimens typically had features of mixed inflammation, fat disruption, and small areas of necrosis.	9111264
Inflammation, Necrosis	Altered Intercellular Communication	Biopsy results show mixed inflammation with evidence of necrosis that must not be regarded as a nonspecific finding.	9111264
Airway structure, Asthma	Altered Intercellular Communication	Measuring airway inflammation in asthma: eosinophils and eosinophilic cationic protein in induced sputum compared with peripheral blood.	9111500
Asthma, Eosinophilic inflammation	Altered Intercellular Communication	Airway eosinophilic inflammation is a characteristic feature of asthma.	9111500
Asthma, Eosinophilic inflammation	Altered Intercellular Communication	We investigated the performance of these markers of airway eosinophilic inflammation in a population of patients with asthma compared with control subjects and the extent to which the markers differed.	9111500
Asthmatic Airway Remodeling	Altered Intercellular Communication	We conclude that the proportion of eosinophils in sputum is a more accurate marker of asthmatic airway inflammation than the proportions of blood eosinophils or serum ECP.	9111500
Hormone abnormality, Primary malignant neoplasm, pituitary dysfunction, Prostate carcinoma	Altered Intercellular Communication	Because prostate cancer is a hormonally responsive cancer, hormonal abnormalities from pituitary dysfunction may have played a role in its development.	9111626
Inflammation, Diverticulitis	Altered Intercellular Communication	Diverticulitis was considered moderate when CT showed localized thickening of the colonic wall (5 mm or more) and inflammation of pericolic fat; it was considered severe when abscess and/or extraluminal air and/or extraluminal contrast were observed.	9112910
Inflammation, Exacerbation of cGVHD	Altered Intercellular Communication	Flare, measured the day before surgery and postoperatively at days 1, 7, 30, and 180, was integrated to obtain a global estimate of inflammation during the 180 day follow-up.	9113574
Inflammation, Colitis	Altered Intercellular Communication	The second episode, at the time of an exacerbation of his colitis, was characterized by moderate portal inflammation on liver biopsy and resolved quickly while he was on corticosteroid therapy.	9113796
Inflammation, Leprosy	Altered Intercellular Communication	These findings provide evidence for a correlation between the expression of TNF-alpha and disease activity suggesting that TNF-alpha is a useful prognostic indicator for inflammation in leprosy.	9115924
Inflammation, Intermediate periventricular nucleus	Altered Intercellular Communication	The findings of this study suggest that there is evidence of inflammation in the airspaces of patients with HPE.	9117030
Inflammation	Altered Intercellular Communication	Inflammation and immune mechanisms are considered important for the pathogenesis of nonrheumatic AVS.	9120159
Inflammation	Altered Intercellular Communication	IP NC growth derived from the adventitia increases with age and is strongly associated with IP cellular inflammation.	9120181
Inflammation	Altered Intercellular Communication	Cyclophilins have been suggested to act as leukocyte chemotactic factors produced in the course of inflammation.	9120404
Inflammation, Ductal Carcinoma	Altered Intercellular Communication	Angiogenesis and inflammation in ductal carcinoma in situ of the breast.	9120726
Inflammation, Noninfiltrating Intraductal Carcinoma	Altered Intercellular Communication	Increased stromal vascularity was associated with the perivascular clusters of inflammation; both were associated with c-erB-2 expression and extent of the DCIS.	9120726
Inflammation, Noninfiltrating Intraductal Carcinoma	Altered Intercellular Communication	Perivascular inflammation and c-erB-2 (but neither pattern of vascularity) were associated with poor differentiation of the DCIS.	9120726
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Inflammation in benign prostatic hyperplasia: correlation with prostate specific antigen value.	9120926
Inflammation, Prostate	Altered Intercellular Communication	Prostatic subclinical inflammation is not associated with high urinary PSA.	9120926
Sepsis, Communicable Diseases	Altered Intercellular Communication	In 35.6% of the cases sepsis was caused by soft tissue infection, in 35.6%-pyo-inflammation of the blood vessels.	9121045
Urticarial vasculitis, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	All studies including skin biopsy for urticarial vasculitis (UV) and systemic lupus erythematosus (SLE) were negative except for the data from non-specific inflammations.	9124057
Diverticulitis	Altered Intercellular Communication	Increased mucosal lymphoplasmacytic inflammation at the bases of the prominent folds was present in 15% and 9% of DD-diverticulitis and DD-adenocarcinoma specimens, respectively.	9124212
Waldenstrom Macroglobulinemia, Diverticulosis	Altered Intercellular Communication	Mildly increased lymphoplasmacytic inflammation surrounded the diverticulosis ostia in approximately 25% of all DD specimens.	9124212
neutrophilic, Waldenstrom Macroglobulinemia, Diverticulitis	Altered Intercellular Communication	All the diverticulitis ostia had neutrophilic and lymphoplasmacytic inflammation in the surrounding mucosa.	9124212
Inflammation, Diverticulum	Altered Intercellular Communication	Diverticular disease-related inflammation may be one cause of mild patchy inflammation that is occasionally observed in sigmoid colon biopsy specimens.	9124212
Granuloma, Crypt	Altered Intercellular Communication	Other diseases should be considered when markedly increased mucosal inflammation, crypt distortion, or granulomas are present.	9124212
Inflammation	Altered Intercellular Communication	These findings indicate that SLPI may play a previously unexpected role in elastase inhibitory function in the lungs when significant inflammation is present.	9124611
Dettol, Bothered by Vomiting, Pharyngitis	Altered Intercellular Communication	Based on information available in published cases and on our own experience, we suggest that patients who have ingested large volumes of Dettol, have a history of vomiting or unprotected lavage, or have evidence of ongoing oropharyngeal inflammation, are at high risk of this complication.	9124667
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	To examine the role of low-grade inflammation in the etiology and progression of early osteoarthritis (OA) of the knee.	9125256
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	CRP levels are modestly but significantly increased in women with early knee OA, and higher levels predict those whose disease will progress over 4 years, suggesting that low-grade inflammation may be a significant aspect of early OA and may be amenable to therapeutic intervention and secondary prevention.	9125256
Inflammation, Communicable Diseases, IGA Glomerulonephritis, Purpura, Fever	Altered Intercellular Communication	An IgA glomerulonephritis was significantly associated with purpura above the waist (P = .03), a recent infectious history (P = .02), pyrexia (P = .01), and biological markers of inflammation (P = .006).	9126006
Communicable Diseases, Fever, Purpura, Inflammation	Altered Intercellular Communication	A recent infectious history, pyrexia, the spread of purpura to the trunk, and biological markers of inflammation were predictive factors for renal involvement.	9126006
Inflammation, Edema	Altered Intercellular Communication	There were desquamated stratified squamous epithelial cells in edema fluid between muscle fibers, surrounded by intense neutrophilic inflammation.	9126047
Inflammation	Altered Intercellular Communication	This inflammation might reflect CNS immune activation in the absence of the relevant antigen, in addition to cellular reactions accompanying secondary CNS changes.	9126057
Refractory anemias, Arthritis	Altered Intercellular Communication	The increased levels of MMP-3 in synovial fluids in RA group may reflect an elevated matrix degrading activity due to joint inflammation.	9128417
Cerebrovascular Disorders, Inflammation	Altered Intercellular Communication	These findings may be relatively specific for inflammation of deep cerebral vessels and have implications for MRI findings in other inflammatory cerebrovascular disorders.	9128453
Cholecystitis	Altered Intercellular Communication	Grade I and II ultrasonographic changes, which indicated chronic inflammation of the biliary tract and gallbladder, were detected in 32% of the infected individuals.	9129534
Keratitis	Altered Intercellular Communication	Primary cornea guttata in subjects without corneal inflammation was defined as dark areas, seen on specular microscopy, and irregular refractile dots, observed with slit-lamp microscopy.	9130056
Inflammation, Necrosis, Mesentery, Fibrosis Assessment, Mesenteric Panniculitis, Hyperplastic Polyp, Retractile Mesenteritis	Altered Intercellular Communication	We reviewed 84 cases coded as mesenteric lipodystrophy (ML), mesenteric panniculitis (MP), or retractile mesenteritis and sclerosing mesenteritis (SM), grading fibrosis, inflammation, and fat necrosis, and evaluating clinical subgroups.	9130985
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	All patients had some degree of fibrosis, chronic inflammation, and fat necrosis.	9130985
Inflammation, Fibrosis Assessment, Hyperplastic Polyp, Necrosis	Altered Intercellular Communication	Although a few patients showed a sufficient prominence of fibrosis, inflammation, or fat necrosis to permit a separation into SM, MP, or ML, respectively, in most patients these three components were too mixed for a clear separation.	9130985
Inflammation, Pyometra, Necrosis	Altered Intercellular Communication	Inflammation and necrosis were present in all cases, and four had features of pyometra.	9130986
Inflammation, Endometrial Endometrioid Adenocarcinoma, Necrosis	Altered Intercellular Communication	This report suggests that endometrioid endometrial carcinoma may rarely be associated with psammoma bodies, the formation of which is most likely due to inflammation and necrosis.	9130986
Cataract, Intraocular inflammation	Altered Intercellular Communication	Diclofenac sodium appears to be more potent than flurbiprofen in controlling intraocular inflammation after cataract surgery, while having better local tolerance than flurbiprofen or indomethacin.	9132126
Inflammation, Perforation (observation)	Altered Intercellular Communication	The elevated rate of appendectomies without histological evidence of acute inflammation, especially in young women, and the high perforation ratio in small children and elderly patients reflect poor diagnostic accuracy.	9132342
submandibular salivary gland formation	Altered Intercellular Communication	In six patients, women of 49, 59, 71, 82, 76 and 64 years old, acute inflammation of parotid and submandibular salivary glands was diagnosed.	9132610
Neoplasms, Fibrosis Assessment, Infection, Vasculitis, CTCAE, Liver Cirrhosis	Altered Intercellular Communication	All available microscopic liver slides from cases in which the autopsy report described portal tract inflammation, fibrosis, cirrhosis, tumour, amyloid, vasculitis, or infections involving the liver were examined and graded by a hepatic pathologist blinded to the original diagnosis, along with a representative sample of cases with reports describing fatty change or no hepatic pathologic abnormalities.	9133932
Communicable Diseases, HIV Infections	Altered Intercellular Communication	HCV infection was associated with a higher degree of portal, periportal and lobular inflammation-regardless of whether there was concurrent HIV infection.	9134037
Malignant neoplasm of testis, Primary malignant neoplasm	Altered Intercellular Communication	The results for testicular cancer gave some support to the hypothesis of a hormonal link between MFs and cancer, and should be further explored.	9134242
Inflammation, Hepatitis C, Chronic active hepatitis	Altered Intercellular Communication	Transcutaneous liver biopsy was performed in five patients with HCV infection, and specimens obtained showed in all cases a chronic active hepatitis with varying degrees of portal inflammation.	9135219
Refractory anemias, Inflammation	Altered Intercellular Communication	These findings suggest that OSM may contribute to joint inflammation in RA.	9135222
Cyst, Inflammation, Dermoid Cyst	Altered Intercellular Communication	The cyst was considered to be the result of inflammation or intracystic auto-digestion by enzymes from the alimentary tissue of the cystic teratoma.	9136540
PROS1 gene, Inflammation, PHB2 gene, Refractory anemias	Altered Intercellular Communication	During the endoscopic examination various degrees of gut inflammation were observed in 13% of ReA, 5% of PsA, 26% of AS, 14% of USpA and 11% of RA patients.	9137322
Granulomatous inflammation	Altered Intercellular Communication	We considered that the bone-cement interface tissue could be the site of granulomatous inflammation caused by a foreign-body reaction.	9138074
Granulomatous inflammation	Altered Intercellular Communication	It has been demonstrated that inflammatory cytokines and chemokines have an important role in granulomatous inflammation.	9138074
Neoplasms	Altered Intercellular Communication	The RI (resistance index) values were analyzed in relation to gross appearance, histological type of the tumor, existence of inflammation/necrosis area and vascularization pattern of the tumor.	9138957
Inflammation, Hemorrhagic, Fibrinous, Ulcer	Altered Intercellular Communication	Advanced inflammation (fibrinous, ulcerative and hemorrhagic) of all colon and distal part of the small bowel was a common finding.	9139607
Icterus, Inflammation	Altered Intercellular Communication	Eighty four (40.2%) were suffering from jaundice on admission (on average 4 days) and 89 (42.6%) showed signs of inflammation.	9141901
Shock, Inflammation	Altered Intercellular Communication	These observations showed that increase of proinflammatory cytokines was a consequence of inflammation, not of shock.	9142024
Inflammation	Altered Intercellular Communication	It is concluded that 99mTc-Infecton imaging contributed to the differential diagnosis of inflammation.	9142737
Inflammation	Altered Intercellular Communication	The presence of peptidergic nerves suggests that ligaments may be susceptible to neurogenic inflammation and may be centres of articular nociception.	9143665
Pain Distress Question, Inflammation	Altered Intercellular Communication	Therefore prudent use of corticosteroids in selected patients with severe pain not responsive to analgesics or severe corneal or anterior chamber inflammation appears justified.	9143798
Inflammatory abnormality of the eye, Traumatic injury, Corneal Diseases	Altered Intercellular Communication	Exclusion criteria included history of either corneal disease, ocular inflammation, trauma, or surgery other than peripheral iridectomy.	9143804
Degenerative polyarthritis, Rheumatoid Arthritis, Refractory anemias	Altered Intercellular Communication	High levels of immunoreactive and biologically active parathyroid hormone-related peptide (PTHrP) were detected in synovial fluids from patients with osteoarthritis (OA) and rheumatoid arthritis (RA).	9144352
Deglutition Disorders, Inflammation, Fever, CTCAE	Altered Intercellular Communication	She presented with dysphagia but no fever or definite laboratory signs of inflammation.	9144677
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	ASAT levels correlated with originally determined histological severity, the numerical Knodell score and the numerical scores for piecemeal necrosis, for intra-acinar necrosis and inflammation and for fibrosis in the Bianchi-Gudat score.	9144972
Inflammation	Altered Intercellular Communication	ALAT levels correlated only with intra-acinar necrosis and inflammation.	9144972
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	Ophthalmic fluorometholone-gentamicin was as effective as ophthalmic betamethasone-gentamicin in the control of ocular inflammation after cataract surgery.	9145693
Inflammation	Altered Intercellular Communication	The appearance of Beau's lines suggested inflammation of the nail matrix.	9146561
Fibrosis Assessment, Bronchitis	Altered Intercellular Communication	(a) TGF-beta is scarse in asthmatic bronchial epithelial cells, which could favour the perennization of the bronchial inflammation, and (b) TGF-beta is present in inflammatory cells beneath the basement membrane, where it could be involved in the frequent sub-epithelial fibrosis.	9146931
Inflammation, Pneumocystis jiroveci pneumonia, Edema, Exudate, Lung diseases	Altered Intercellular Communication	P carinii pneumonia was characterized by an increase in inflammation, edema, exudate, fibrosts, type II pneumocyte proliferation, and cellular infiltration of the alveolar wall when compared with other lung diseases (all p < 0.05).	9149569
Inflammation, Pneumocystis jiroveci pneumonia, Alveolar Epithelial Cells, Interstitial Fibrosis Assessment	Altered Intercellular Communication	Inflammation, interstitial fibrosis, and alveolar epithelial erosion are characteristic features of P carinii pneumonia.	9149569
Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	The aim of the present study was to determine whether or not the altered accessory cell function of AMs could account for the Th2 pattern of chronic inflammation in IPF.	9150314
Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Thus, the altered accessory cell function of alveolar macrophages from patients with idiopathic pulmonary fibrosis may possibly relate to the pattern of type-2 T-helper cytokine production in response to inflammation.	9150314
Pneumonitis	Altered Intercellular Communication	In animal models of pulmonary inflammation, neutrophils exhibit a dramatic influx of glucose in periods of high metabolic activity.	9150315
Inflammatory abnormality of the eye, Glaucoma, CTCAE	Altered Intercellular Communication	Intraoperative mitomycin-C for glaucoma associated with ocular inflammation.	9150520
Inflammatory abnormality of the eye, Glaucoma, CTCAE	Altered Intercellular Communication	The authors studied the efficacy and complications of intraoperative mitomycin-C in glaucoma associated with ocular inflammation.	9150520
Inflammatory abnormality of the eye, Glaucoma, CTCAE	Altered Intercellular Communication	The authors retrospectively reviewed the medical records of 24 consecutive patients (24 eyes) with glaucoma and ocular inflammation who had been treated with trabeculectomy and intraoperative mitomycin-C.	9150520
Inflammatory abnormality of the eye, Glaucoma, CTCAE	Altered Intercellular Communication	Trabeculectomy with mitomycin-C can control intraocular pressure in glaucoma associated with ocular inflammation, but complications are frequent.	9150520
MENTAL RETARDATION, X-LINKED, SNYDER-ROBINSON TYPE, Adenoma	Altered Intercellular Communication	SRS results were not related to the immunohistological subtype in 22 GH-A (monohormonal mixed somatotrope/lactotrope, plurihormonal) or in 22 NF-A (null-cell adenomas, gonadotropinomas silent hormonal adenomas).	9150695
Inflammation, Postoperative Period, Anemia	Altered Intercellular Communication	RHuEPO (50-280 U/kg body weight) was daily administered to 4 of the patients, who either exhibited preoperative anaemia or developed postoperative anaemia refractory to endogenous EPO probably due to inflammation.	9150708
Inflammation	Altered Intercellular Communication	Changes in TGF-beta 1 levels in gingiva, crevicular fluid and serum associated with periodontal inflammation in humans and dogs.	9151066
Eosinophilic inflammation, Acute bronchiolitis	Altered Intercellular Communication	In addition, the same parameters of eosinophil inflammation were examined in serum samples from 25 children aged 1-17 months undergoing their first episode of acute bronchiolitis.	9151339
Inflammation, Bronchiolitis	Altered Intercellular Communication	The results suggest that the inflammation in RSV bronchiolitis differs from that induced by other viruses.	9151339
Inflammation, Candida parapsilosis	Altered Intercellular Communication	The long-term inflammation resolved, and vitreous cultures from both eyes yielded Candida parapsilosis.	9152139
Inflammation, Purulence, pathologic fistula, Crohn Disease	Altered Intercellular Communication	Reasons for resection included significant purulence or inflammation, a large fistula defect, a defect on the mesenteric border of the sigmoid, and active sigmoid Crohn's disease.	9152183
Crohn Disease, Inflammation	Altered Intercellular Communication	Surgeon's assessment of the presence of Crohn's disease in the sigmoid correlated with pathologic examination and was aided by knowledge of recent endoscopic appearance and biopsy results; intraoperative frozen section and colonoscopy were helpful in distinguishing serosal inflammation from active Crohn's disease.	9152183
Viral Respiratory Tract Infection, Pulmonary Edema, CTCAE	Altered Intercellular Communication	We investigated retrospectively whether the preexistence of inflammation-producing illnesses such as viral respiratory tract infections contributed to the development of high-attitude pulmonary edema in children.	9152300
Phlegmonous enteritis	Altered Intercellular Communication	Phlegmonous enteritis is a rare infective inflammatory condition of the gut which is difficult to diagnose and which is often fatal.	9153817
Allergic, Inflammation, Data types - Address, Immediate hypersensitivity	Altered Intercellular Communication	level is related to the development of the allergic cellular inflammation representing the pathology of AD, rather than the IgE-mediated allergic reaction as a mechanism of childhood BA.	9154699
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Eosinophilic inflammation has been observed in the airways of patients with chronic obstructive pulmonary disease (COPD).	9154853
ARCN1 gene, Inflammation, Asthma, Thickened	Altered Intercellular Communication	A subset of patients clinically diagnosed as having COPD show a reversibility of airflow obstruction when treated with corticosteroids, and may consist of patients with features of asthma including reticular basement membrane thickening and eosinophilic inflammation.	9154853
Gastroesophageal reflux disease, Inflammation, Gastric Infection	Altered Intercellular Communication	As inflammation is known to be associated with neural activation an investigation was made to determine whether gastric infection with H pylori is altered in prevalence or distribution in patients with reflux disease.	9155568
Airway structure	Altered Intercellular Communication	However, because direct measurement of endogenous NO has been difficult in vivo, the exact pathologic roles of NO in human airway inflammation have remained unclear.	9155829
Airway structure, allergic inflammation	Altered Intercellular Communication	This study was designed to determine whether NO may be harmful by amplifying allergic inflammation in asthmatic airways.	9155829
allergic inflammation	Altered Intercellular Communication	The clinical implication of our findings is that measurement of NO derivatives in induced sputum may be useful for assessing allergic inflammation in airways.	9155829
Inflammation, Neoplasms, Abnormal	Altered Intercellular Communication	Their concentrations vary physiologically with age but also in diseases such as inflammation, neoplastic tumours or in inborn genetic disorders causing abnormal sialic acid metabolism.	9156567
Intestinal Atresia, Anus, Imperforate, Tissue Adhesions, Peritonitis	Altered Intercellular Communication	The extensive peritoneal drainage fosters capture of enteric fistulas with the formation of enterostomies at drain exit sites, while adhesions and ischemia/inflammation-induced hypervascular obliteration of the peritoneal cavity diminish the potential for peritonitis (no peritoneal cavity, no peritonitis) and facilitate impressive salvage of seemingly hopelessly lost ischemic/necrotic gut (a simulation of the in utero ischemic gut process leading to atresias and some varying, but generally mild, gut loss) while simultaneously contributing to the resorption of absolutely non-salvageable gut and the creation of a remarkably clean and adhesion-free peritoneal cavity resembling that of a newborn infant with midgut intestinal atresia.	9156865
Fever, CTCAE	Altered Intercellular Communication	A drop in blood pressure, loose stools, upper respiratory inflammation, and fever were most frequent adverse reactions.	9156934
Inflammation, liposarcoma	Altered Intercellular Communication	The presence of abundant inflammation is uncommon in well-differentiated liposarcomas (WDLPS).	9158675
Inflammation	Altered Intercellular Communication	Microscopically, all lesions were characterized by nodular calcium in a background of degenerating blood elements and chronic inflammation.	9158709
Inflammation	Altered Intercellular Communication	Thus, there are two separate independent factors predicting Salb--markers of inflammation and protein intake--but high concentrations of acute-phase proteins have a greater impact on Salb than does low PCRn.	9159298
Acute inflammation	Altered Intercellular Communication	There were no significant differences between groups in postoperative inflammation.	9159691
Gingivitis, Inflammation	Altered Intercellular Communication	Gingival inflammation associated with foreign bodies in connective tissue is termed foreign body gingivitis.	9159816
Inflammation, Granulomatous	Altered Intercellular Communication	The inflammation frequently was granulomatous and sometimes lichenoid.	9159816
Inflammation, Fibrosis Assessment, Tympanosclerosis, Hyperkeratosis	Altered Intercellular Communication	Beside excessive thickening of the tympanic membrane in 73%, all membranes showed other histological abnormalities: inflammation (97%), excessive fibrosis (97%), tympanosclerosis (80%), hyperkeratosis (83%), rete riges (43%) and epithelial inclusions (6%).	9160932
Data types - Address	Altered Intercellular Communication	GAL modulates the release of acetylcholine and, therefore, may depress this neurotransmitter in surviving cholinergic basal forebrain (CBF) neurons in AD.	9161723
Autoimmune Diseases, Inflammation, Wounds and Injuries	Altered Intercellular Communication	The etiology of this disease is still unknown even if various factors such as inflammation, autoimmunity or traumas are involved.	9162376
Communicable Diseases, Inflammation, Lymphoma	Altered Intercellular Communication	The replication error phenotype (RER+), as revealed by widespread microsatellite instability, is caused by defects in DNA mismatch repair genes, and has been frequently disclosed in subsets of B-cell lymphomas with underlying infection and chronic inflammation.	9163616
Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	These findings suggest that elevated P-III-P level is accompanied by an increase in lymphocyte population in BALF from IPF patients, resulting in a longer duration of the disease, while elevated TGF-beta level reflects alveolar inflammation at an earlier stage of the disease which induces a progression of the disease, resulting in a shorter survival in IPF patients.	9163845
Inflammation, Vasculitis, CTCAE, Eosinophilic inflammation	Altered Intercellular Communication	A sural nerve biopsy showed necrotizing vasculitis and inflammation with eosinophil infiltration.	9164142
Inflammation, Liver carcinoma	Altered Intercellular Communication	We recently demonstrated that an activated inflammation in a non-tumorous portion was a significant risk factor for recurrence in patients with small hepatocellular carcinoma.	9164522
Inflammation, Recurrent Intrahepatic Cholestasis	Altered Intercellular Communication	The enhancement of inflammation in the remnant liver tissue is related to intrahepatic recurrence after hepatic resection through adhesion molecules, such as cICAM-1.	9164522
Inflammation, Colonization, Chronic Kidney Diseases	Altered Intercellular Communication	To evaluate the function of the biliary sphincter 15 to 17 years after endoscopic sphincterotomy and to investigate if loss of sphincter function is associated with bacterial colonization, changes in bile composition, or inflammation of the biliary system.	9165322
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Biopsy specimens of the proximal common hepatic duct in three patients showed chronic inflammation with fibrosis and reactive epithelial changes.	9165322
Inflammation, Colonization	Altered Intercellular Communication	This is associated with bacterial colonization, presence of cytotoxic components in the bile, and chronic inflammation of the biliary system.	9165322
Granuloma, Kaposi Sarcoma, Inflammation, Lymphoma	Altered Intercellular Communication	Thirty-three were diagnosed as reactive lymph nodes, 15% as benign lymphoepithelial lesions and 9% as granulomas; 9% revealed acute inflammation, 5% were positive for malignant lymphoma, and 3% were suspicious for Kaposi's sarcoma.	9167706
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In conclusion, rectal dialysis is a non-invasive technique that allows to prove the presence of active inflammation in ulcerative colitis patients.	9168661
Inflammation, Ascites, Thickened, Lymphadenopathy, Amputation	Altered Intercellular Communication	Imaging features that suggest the correct diagnosis are cecal amputation, ileocecal thickening and inflammation, shortening of the ascending colon, gaping of the ileocecal valve, mesenteric adenopathy, a misty mesentery, diffuse omental infiltration, loculate high-density ascites, an enhancing peritoneum with or without an omental line, nodularity of the surface of the mesenteric leaves, and transperitoneal permeation.	9168707
Inflammation, Vasculitis, CTCAE, Ischemia	Altered Intercellular Communication	Diagnoses were classified as inflammation (n = 25), vasculitis (n = 7), or ischemia (n = 5) and were confirmed with findings from colonoscopy and biopsy, stool culture analysis, surgery, and cutaneous biopsy, and with a combination of clinical and laboratory data.	9169680
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Older patient age and visible color Doppler flow suggested inflammation, whereas younger patient age and visible color flow suggested vasculitis.	9169680
Gingivitis, Attachment (action), HIV	Altered Intercellular Communication	Human immunodeficiency virus (HIV)-seropositive patients have frequently severe gingival inflammation and/or attachment loss.	9171509
Aneurysm, Structure of iliac artery, Number of Renal Arteries, Inflammation	Altered Intercellular Communication	The following features were assessed: renal artery number and disease; upper and lower aneurysm extent; aneurysm size; perianeurysmal inflammation; iliac artery disease; radiation dose; and contrast usage.	9171791
Inflammation	Altered Intercellular Communication	A permanent increase of alpha 1-acid glycoprotein fucosylation indicates persisting inflammation.	9173750
Inflammation	Altered Intercellular Communication	One hypothesis to explain this association is that inflammation of the peripheral airways caused by pollution might increase blood coagulability.	9174559
Degenerative polyarthritis, Inflammation, Refractory anemias	Altered Intercellular Communication	Clinical assessment of inflammation (0-6) was undertaken on OA and RA knees.	9175930
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Clinical subgrouping and local joint inflammation may influence these measures, supporting different pathogenesis within OA subgroups and requirement for careful patient characterisation in SF studies.	9175930
Inflammation, Granulomatosis with polyangiitis	Altered Intercellular Communication	Granulomatous inflammation of the stomach, although a rare finding and non-specific, should include Wegener's disease in the differential diagnosis.	9176088
Communicable Diseases, Inflammation	Altered Intercellular Communication	Median (range) SAA on admission was 98 (0.1-940) mg/ml in patients with infection and was twice that observed in patients with other causes of inflammation, median value 50 (0.6-699) mg/l.	9177673
Communicable Diseases, Inflammation	Altered Intercellular Communication	There was no difference between median CRP on admission in patients with infection or inflammation, median value 53 (0.1-235) and 51.5 (5-246) mg/l respectively.	9177673
Neoplasm Metastasis, Neoplasms, Vascular Invasion Assessment, Chronic lymphocytic inflammation, TNM Staging System, Infiltration	Altered Intercellular Communication	Univariate Kaplan-Meier survival analysis showed prognostic significance of the following: Dukes staging, individual components of TNM stage (tumor depth, lymph node status, and metastasis), vascular invasion, histologic pattern of tumor infiltration, and peritumoral lymphocytic inflammation.	9179053
Axonal degeneration, Inflammation, Primary demyelination	Altered Intercellular Communication	We conclude that both primary demyelination and axonal degeneration secondary to inflammation account for nerve inexcitability.	9179157
Inflammation, Osteopenia	Altered Intercellular Communication	Since both NO and PGE2 have been implicated in the induction and maintenance of chronic inflammation with resulting loss of bone, and peroxynitrite in the pathogenesis of disease states, they may be central to the pathogenesis of aseptic loosening.	9180331
Intraocular inflammation	Altered Intercellular Communication	However, limited information is available about the advantages of the HSM IOL in patients with an intraocular inflammation.	9181331
Intraocular inflammation	Altered Intercellular Communication	The activity of intraocular inflammation, visual acuity, eventual complications, and medications were examined.	9181331
Inflammation	Altered Intercellular Communication	Non-specific chronic inflammation was also present in the walls.	9182301
Eosinophilic cystitis	Altered Intercellular Communication	Eosinophilic cystitis is an inflammatory condition whose etiopathogenesis remains to be elucidated.	9182498
Cheilitis, Inflammation	Altered Intercellular Communication	Angular cheilitis and inflammation under removable dentures were more frequent in women than in men.	9183025
Inflammation	Altered Intercellular Communication	Adult supraglottitis is an acute inflammation of the supraglottic structures first reported by Shapiro et al.	9184030
Tissue damage, Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Abnormalities in production may be associated with inflammation and fibrinolysis at sites of tissue damage such as the atherosclerotic plaque.	9184409
Pancreatitis	Altered Intercellular Communication	Acute pancreatitis was diagnosed on the basis of a mildly elevated amylase concentration (392 U/L) and radiologic evidence of pancreatic inflammation.	9184712
Inflammation, Hematoma	Altered Intercellular Communication	Chronic inflammation at this site appeared to have caused the hematoma.	9185449
Acute inflammation, Stenosis of bronchus	Altered Intercellular Communication	[A case of bronchial stenosis due to postoperative inflammation treated with expandable metallic stent].	9185452
Spinocerebellar Ataxia Type 7, Retinal pigment epitheliitis	Altered Intercellular Communication	The pigmentary maculopathy of acute retinal pigment epitheliitis may be nonspecific, resulting from more than one type of primary foveal inflammation.	9186111
Inflammation, Retinitis	Altered Intercellular Communication	The inflammation responded well topical, oral, and intravenous administration of corticosteroids, the choice of which was based on the extent of retinal inflammation.	9186433
Inflammation, Necrosis	Altered Intercellular Communication	Histologically scarification, necrosis and signs of severe inflammation of the mucosa were seen in 76.9% of this group.	9186837
Presenile dementia, Corticobasal degeneration, Neuropathologist	Altered Intercellular Communication	We detail findings of neurotransmitter derangement in the basal ganglia of a case of neuropathologically confirmed corticobasal degeneration, who presented with dementia.	9188904
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	Primary Sjogren's syndrome is a disease with inflammation not only in the salivary and lacrimal glands but also in the pulmonary alveoli and the bronchi.	9188924
Inflammation, Asthma, Hyperreactivity	Altered Intercellular Communication	There is not a perfect correlation between inflammation and hyperreactivity even in asthma.	9188924
Symptoms, Bronchitis	Altered Intercellular Communication	Even in the bronchial inflammation and the asthma symptoms are easy to treat with anti-inflammatory medicines, a considerable component of BHR usually still remains, as measured with methacholine or histamine.	9188924
Inflammation, Bronchiectasis, Necrosis	Altered Intercellular Communication	The second pattern (n = 4) was that of a granulomatous bronchiectatic cavity with a central fungus ball and subtle tongues of necrosis and inflammation extending into and through the fibrous wall of the cavity.	9190998
Inflammation, Granuloma	Altered Intercellular Communication	The hands were examined for areas of inflammation, granuloma formation and abnormal scar formation.	9193271
Reproductive dehiscence, Inflammation	Altered Intercellular Communication	Resection and primary anastomosis has not generally been recommended when the clinical setting is compromised by contiguous inflammation or inadequate mechanical cleansing of the colon because of concerns regarding the potential risk of anastomotic dehiscence.	9194460
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Angina Pectoris, Cardiovascular Diseases	Altered Intercellular Communication	Markers of inflammation, such as C-reactive protein (CRP), are related to risk of cardiovascular disease (CVD) events in those with angina, but little is known about individuals without prevalent clinical CVD.	9194763
Upper Respiratory Infections	Altered Intercellular Communication	Whether increased NO output depends on respiratory tract inflammation, as the relationship with MEF25 may suggest, or on circulating cytokines produced elsewhere remains to be investigated.	9195510
Necrotizing granulomatous inflammation, Fibrosis Assessment	Altered Intercellular Communication	Extensive myocardial fibrosis, with lymphocytic and granulomatous inflammation, was demonstrated at autopsy.	9195567
Inflammation, Bronchiectasis	Altered Intercellular Communication	In conclusion, aerosolized GM is effective in improving airway hypersecretion and inflammation in patients with bronchiectasis.	9196111
Pheochromocytoma, Inflammation	Altered Intercellular Communication	Interleukin-6 secreting phaeochromocytoma associated with clinical markers of inflammation.	9196615
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	Tear lactoferrin concentration during postoperative ocular inflammation in cataract surgery.	9197559
Inflammation, Chronic cholecystitis	Altered Intercellular Communication	Furthermore no significant difference was found between patients with histopathologically proven acute inflammation and patients with an acute episode of chronic cholecystitis.	9198565
Pachymeningitis, Pituitary Gland	Altered Intercellular Communication	However, an association between pachymeningitis and pituitary inflammation has not been recognized previously.	9199686
Inflammation	Altered Intercellular Communication	Microleakage is related to recurrent decay, inflammation of vital pulps, and reinfection of previously treated root canals.	9200198
Inflammation	Altered Intercellular Communication	Patients with primary SS displayed a significantly higher degree of salivary gland inflammation and reduced salivary flow than did patients with secondary SS.	9201311
Granulomatosis with polyangiitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	In the initial inflammatory process of Wegener's granulomatosis, it is not possible to differentiate between mucosal inflammation and granulomatous tissue in MRI.	9204342
Inflammation	Altered Intercellular Communication	Within areas of inflammation, several follicles converge toward a common follicular duct with a widely dilated opening.	9206717
Chronic prostatitis, prostatitis	Altered Intercellular Communication	Group 1 patients had no prostatic inflammation, group 2 patients had combination of BPH with chronic prostatitis.	9206881
Communicable Diseases, Inflammation	Altered Intercellular Communication	TRT complications comprise mainly infection and inflammation (11.1%).	9206882
Inflammation, Chronic maxillary sinusitis	Altered Intercellular Communication	We have recently phenotyped inflammation in non-infectious allergic and non-allergic chronic maxillary sinusitis using sinus biopsies and lavage fluids.	9208188
Communicable Diseases, Inflammation	Altered Intercellular Communication	Chronic persistent H pylori infection was associated with a low PG I:II ratio, increased inflammation and activity score, and elevated cell proliferation, as evidenced by the Ki67 and PCNA labeling indexes and the mitotic index in the NE group.	9208975
Inflammation, Lower respiratory tract infection	Altered Intercellular Communication	The present result suggests that IL-6 and TNF-alpha may have relationship with not only inflammation in airway but also indices of nutrition in patients with chronic lower respiratory tract infection.	9209124
Communicable Diseases, Inflammation	Altered Intercellular Communication	Scleral buckle infection should be suspected and removal of buckling materials should be considered, in cases with refractory conjunctival and scleral inflammation even years after scleral buckling procedure.	9209141
Inflammation, Ischemia	Altered Intercellular Communication	A direct effect of inflammation as well as ischemia in the retina may have been the stimulus for the proliferative changes.	9209143
bone destruction, Chronic inflammation, Pannus, Swelling, Ankle joint structure	Altered Intercellular Communication	At age 5 weeks, swelling of the bilateral ankle joints histologically showing synovial lining hyperplasia, severe chronic inflammation, erosion of the joint cartilage, and bone destruction with pannus formation began to develop in these env-pX rats.	9209358
Inflammation, Intervertebral Disc Degeneration	Altered Intercellular Communication	We conclude that posterolateral lumber fusion has a less predictable result for the subset of degenerative disc patients with abnormal endplates and associated marrow inflammation.	9209879
Inflammation, Athletic Injuries	Altered Intercellular Communication	As is the case with the rotator cuff complex, overuse inflammation and partial tears of the quadriceps and patellar tendons are one of the most characteristic athletic injuries.	9211611
Tears body substance	Altered Intercellular Communication	Partial tears and inflammations of the rotator cuff complex are much more frequent in throwing sports.	9211611
Inflammation, polyps	Altered Intercellular Communication	The foreign bodies were associated with slight inflammation and polyps on the bronchial epithelium.	9212671
Inflammation, Dryness (characteristic)	Altered Intercellular Communication	Icelandic Moss (Cetraria islandica) has been used to treat inflammation and dryness of the pharyngeal mucosa in the naturopathy for many years.	9213408
Inflammation, Dryness (characteristic)	Altered Intercellular Communication	These patients suffer especially from dryness and inflammation of the oral cavity due to breathing only through the mouth while the nose is permanently closed by a nasal package.	9213408
Inflammation, Sore to touch, Dryness (characteristic), Hoarseness	Altered Intercellular Communication	Three groups of patients treated with three different concentrations of the active substance were compared, Coating, dryness, and inflammation of the mucosa, lymph nodes, tongue, the tolerance of the drug, and symptoms like hoarseness and sore throat were documented.	9213408
Inflammation, Disease	Altered Intercellular Communication	Masquerade syndromes comprise a number of diseases imitating as to their clinical picture inflammation of the eye.	9213521
Benign Prostatic Hyperplasia	Altered Intercellular Communication	[Impact of prostatic benign hyperplasia and prostatic inflammation on the increase of prostate specific antigen levels].	9214204
Synovitis, Joint structure of shoulder region, Girdle, Musculoskeletal Pain, Structure of deltoid muscle, Tenosynovitis	Altered Intercellular Communication	Inflammation of subacromial and subdeltoid bursae in association with synovitis of the glenohumeral joints and tenosynovitis of the biceps may contribute to the diffuse discomfort in the shoulder girdle observed in patients with polymyalgia rheumatica.	9214249
Inflammation, Cutaneous Fistula, Specimen Source Codes - Abscess, Hernia	Altered Intercellular Communication	This complication needs to be added to the differential diagnosis in patients who present inflammation, abscess formation, or cutaneous fistula following laparoscopic hernia repair.	9214331
Necrotizing granulomatous inflammation	Altered Intercellular Communication	To determine the causes of ovarian granulomatous inflammation and to discuss the differential diagnoses.	9215150
Granulomatous inflammation	Altered Intercellular Communication	In five cases, no cause was apparent for the granulomatous inflammation.	9215150
Necrotizing granulomatous inflammation	Altered Intercellular Communication	The study confirms the wide range of conditions which can give rise to ovarian granulomatous inflammation.	9215150
Mastitis, Inflammation, Inflammatory Myofibroblastic Tumor	Altered Intercellular Communication	Before arriving at the correct diagnosis, four biopsies had been performed with various diagnoses of chronic inflammation, plasma cell mastitis and inflammatory pseudotumor.	9216125
Inflammation, Psoriasis	Altered Intercellular Communication	There were no signs of stromal inflammation except in one psoriasis patient.	9217818
Inflammation, Chronic infectious disease	Altered Intercellular Communication	We also studied its relationship with various types of inflammation, including chronic infection, that may be the stimulus for the appearance of CPU.	9218015
Intestinal metaplasia, Inflammation, Superficial ulcer, Atrophic	Altered Intercellular Communication	Each slide was scored for presence, absence and density of H. pylori, active and chronic inflammation, intestinal metaplasia, erosions and atrophy.	9218077
Communicable Diseases, Inflammation	Altered Intercellular Communication	Technetium (99m-Tc)-labelled, polyclonal human immunoglobulin (HIG) has been described as a new agent to detect local infection and inflammation.	9220443
Exophthalmos, Orbital Pseudotumor	Altered Intercellular Communication	A 61-year-old man had signs of right proptosis and orbital inflammation that resolved with oral corticosteroid therapy.	9222254
Nausea, Inflammation, Myalgia, CTCAE 5	Altered Intercellular Communication	Orbital inflammation later recurred with associated cutaneous nodules, myalgia, nausea, and malaise.	9222254
Cholangiocarcinoma, Inflammation, Bile Duct Neoplasms, Pancreatic carcinoma	Altered Intercellular Communication	Pathologic reports included pancreatic head carcinoma n = 2, cholangiocarcinoma n = 3, hepatoma with intrahepatic-bile duct invasion n = 3, common bile duct tumors n = 3 and chronic inflammation n = 1.	9222687
Hypospadias, Kidney Diseases	Altered Intercellular Communication	Control serum specimens were obtained from 63 age matched boys undergoing minor surgery with no evidence of hypospadias, or testicular, hormonal or renal diseases.	9224372
Inflammation	Altered Intercellular Communication	Histopathologic analysis showed a nonspecific necrotizing granulomatous inflammation consistent with but not diagnostic of CSD.	9224472
Cat-Scratch Disease, Localized enlarged lymph nodes, Conjunctivitis	Altered Intercellular Communication	Cat scratch disease due to B. henselae should be suspected in patients with atypical conjunctival inflammation associated with regional lymphadenopathy.	9224472
Conjunctivitis	Altered Intercellular Communication	In this case, surgical excision hastened resolution of the conjunctival inflammation.	9224472
Inflammation, Peritonitis	Altered Intercellular Communication	Peritonitis is inflammation of the serosal surfaces lining the peritoneal cavity which envelopes the bowel, giving a pattern of diffuse abdominal uptake on imaging.	9225807
Inflammation, Tooth Loss, Osteopenia	Altered Intercellular Communication	PTM prevalence of 55.8% was found, and it was statistically associated with bone loss (p<0.001), tooth loss (p<0.001) and gingival inflammation (p<0.001), while no association was observed with the remaining variables.	9226390
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To investigate the potential of quantitative magnetic resonance imaging (MRI) to differentiate between therapeutically induced changes in inflammation and synovial proliferation in rheumatoid arthritis (RA) of the knee.	9227168
Crying	Altered Intercellular Communication	There is increasing evidence that serotonergic neurotransmission may be damaged in poststroke pathological crying.	9227702
Inflammation, Chronic gastritis	Altered Intercellular Communication	For histological evidence of inflammation the tissue was stained with hematoxylin and eosin and classified as mild, active, chronic and chronic active gastritis.	9228556
Inflammation	Altered Intercellular Communication	Audiological examination including routine methods, tonal threshold audiometry (10000-20000 Hz frequency range), noise resistance of the acoustic analyzer in contralateral masking with noises of different intensity has been made to identify early subclinical neurosensory hypoacusis in 96 patients with acute and chronic inflammation of the middle ear aged 17-75 years.	9229915
Inflammation, Hemorrhage, Sinusitis, Congestion	Altered Intercellular Communication	Sections of the sinonasal mucosa revealed marked acute and chronic sinusitis with inflammation, congestion, and hemorrhage.	9230398
Inflammation, Fibrosis Assessment, Idiopathic Pulmonary Fibrosis, Alveolitis	Altered Intercellular Communication	In IPF, active alveolitis or acinitis played a major role in producing low D/Q regions impeding gas exchange via a diffusion limitation, whereas extensive fibrosis with minimal inflammation accounted for low D/Q as well as low VA/Q regions.	9230730
Inflammation, Laryngeal neoplasm	Altered Intercellular Communication	A case of severe inflammation with an exuberant granulation lesion of the larynx that mimicked laryngeal tumour is presented.	9231095
Inflammation, Hoarseness	Altered Intercellular Communication	A patient who was a chronic smoker, with a history of hoarse voice underwent multiple endoscopies and biopsies, confirmed histopathologically as acute and, subsequently, as chronic inflammation.	9231095
Epilepsy, Sibling	Altered Intercellular Communication	Animal models of SIB suggest that the glutamate neurotransmitter systems, involved in the generation of epileptic seizures, may also have a role in the pathophysiology of SIB.	9231320
Hypertension, CTCAE	Altered Intercellular Communication	Because obesity-associated hypertension has unique hemodynamic and hormonal profiles, certain classes of antihypertensive agents may be more effective than others as monotherapy.	9231834
Acute hemorrhage, Intra-abdominal	Altered Intercellular Communication	The diagnosis should be suspected if acute bleeding occurs during the course of severe intra-abdominal inflammation.	9231852
Inflammation, Chief complaint (finding)	Altered Intercellular Communication	Further, the chief complaint involving oral soft tissues was due to inflammation.	9232965
Refractory anemias, Inflammation	Altered Intercellular Communication	The clinical features, blood biochemistry and activity of inflammation were examined in RA patients.	9236672
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	Inflammation, activity, atrophy, and intestinal metaplasia were predominantly grade 1 and H pylori density was predominantly grade 2.	9239907
Inflammation, Atrophic	Altered Intercellular Communication	Inflammation was more severe in the antral lesser curvature and the more severe atrophy was present in the antrum than in the corpus mucosa.	9239907
Inflammation, Atrophic	Altered Intercellular Communication	The presence of H pylori was directly correlated with inflammation severity and inversely with atrophy.	9239907
Communicable Diseases, Inflammation	Altered Intercellular Communication	Through nasopharyngeal endoscopy in the adenoidectomized children in the 6 months following surgery, we noted decreased evidence of infection and/or inflammation.	9241373
Traumatic injury, Prostate carcinoma, prostatitis	Altered Intercellular Communication	Serum prostate-specific antigen (PSA) values above 10 ng/ml are considered highly sensitive and specific for prostatic carcinoma in the absence of prostatic inflammation or trauma.	9241551
Pain Distress Question, Inflammation, Suppurative inflammation	Altered Intercellular Communication	The 9 with pain alone ranged from 25 to 44 years of age, whereas the 17 patients with inflammation ranged from 29 to 67 years of age, and non-contact to adjacent tooth was associated with purulent inflammation in older patients, indicating completely impacted lower third molars may cause pain only until 45 years of age; but purulent inflammation occurs even in the group of non-contact to adjacent tooth after 45 years of age.	9241923
Psoriatic Juvenile Idiopathic Arthritis, Inflammation, Psoriasis, Dermatitis	Altered Intercellular Communication	The ratio of keratinocytic proliferation fraction to endothelial cell proliferation fraction of the psoriatic and spongiotic lesions suggested the presence of different reaction patterns to inflammation in psoriasis and spongiotic dermatitis.	9243363
Cardiac cachexia, Chronic heart failure	Altered Intercellular Communication	Hormonal changes and catabolic/anabolic imbalance in chronic heart failure and their importance for cardiac cachexia.	9244221
Inflammation	Altered Intercellular Communication	inflammation, number of T-helper cells and beta-receptors, allergen contact a.o.--influence this process leading to a deterioration of bronchial reactivity and lung function.	9244892
Failure (biologic function), Tooth structure, Perforation (observation), Fracture	Altered Intercellular Communication	Complications occurred in 9.6% cases: perforation of the wall of the root canal (1.14%), failure of cementing (3.98%), fracture of the root (1.14%), breaking of a fragment of the root at the neck of the tooth (2.84%), and inflammations of the marginal periodontium (0.57%).	9245011
Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	To determine whether this cytokine is involved in gastric mucosal inflammation in Helicobacter pylori infection.	9245927
Inflammation	Altered Intercellular Communication	There was a significant correlation overall between IL-10 secretion and chronic inflammation score (r = 0.40).	9245927
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Secretion of TNF-alpha, which was significantly higher in H pylori infected patients than uninfected patients with a normal mucosa (p < 0.04), correlated with scores for chronic inflammation and activity (r = 0.39 and 0.38 respectively), but was only weakly correlated with IL-10 secretion (r = 0.22, NS).	9245927
Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Gastric mucosal production of IL-10 and TNF-alpha are increased in chronic gastritis associated with H pylori infection, and mucosal cytokine secretion varies with important histopathological aspects of gastric inflammation.	9245927
Tissue damage, Inflammation	Altered Intercellular Communication	Whereas the secretion of IL-10 in H pylori infection may be protective, limiting tissue damage caused by inflammation, it may also contribute towards failure of the immune response to eliminate the organism.	9245927
Neoplasms	Altered Intercellular Communication	Overall, our present results do not support the notion that hormonal changes, or other physiological changes induced by childbearing, play an important role in the development of brain tumors.	9247278
Inflammation, Specimen Type - Fistula, Radiation injury, Malignant Neoplasms, Intestinal Obstruction	Altered Intercellular Communication	Single-stage operation for enterovesical fistula should be limited to those patients in good nutritional state and without severe inflammation, radiation injury, intestinal obstruction, other major medical problem, advanced malignancy or old age.	9248120
Tuberculosis, Pulmonary	Altered Intercellular Communication	The case is 51 year-old male who had been suffering from undetected pulmonary tuberculosis visited a dentist because of chronic periodontal inflammation around the gingiva of the right upper and left lower molar teeth lasting for one year.	9248275
Inflammation	Altered Intercellular Communication	Transmission electron microscopy confirmed complete absence of Bowman's layer without evidence of scarring or inflammation.	9248835
Inflammation	Altered Intercellular Communication	Within the zones of inflammation, the polyethylene skeleton of the implant was extensively damaged.	9248842
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	Indicators of salivary gland inflammation in primary Sjogren's syndrome.	9249189
Inflammation, "Primary Sj√∂grens syndrome	Altered Intercellular Communication	The aim of this study was to establish additional indicators in saliva and plasma which are associated with salivary gland inflammation in patients with primary Sjogren's syndrome (SS).	9249189
Down Syndrome, Inflammation	Altered Intercellular Communication	Gingival inflammation in Down's syndrome children (DS) develops earlier and is more rapid and extensive than in non-DS children.	9249633
Inflammation	Altered Intercellular Communication	Abnormalities in host response to the oral flora have been proposed as etiological factors of this gingival inflammation.	9249633
Inflammation, Aphthous Stomatitis, Crohn Disease	Altered Intercellular Communication	As the level of inflammation progressed in Crohn's disease the blood flow values gradually decreased; the exudative stage of Crohn's disease (aphthoid ulcer) showed blood flow values that were slightly below those in macroscopically normal tissue.	9250891
Crohn Disease, Inflammation	Altered Intercellular Communication	These results are the first to demonstrate decreased blood flow in affected lesions in Crohn's disease and changes in blood flow according to the degree of inflammation in vivo.	9250891
Inflammation	Altered Intercellular Communication	The difference, M(R) - O, was found to have a significant correlation with the average visual grading of the severity of inflammation of the maxillary sinus by 10 otolaryngologists.	9251858
Inflammation	Altered Intercellular Communication	About 1% of dividing epithelial cells in esophageal, gastric and duodenal mucosas with chronic inflammation have been found to be atypical.	9252704
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	In the present work, the characteristics of the mitotic figures in the colorectal mucosa with ulcerative colitis (UC)--a disease characterized by chronic mucosal inflammation--were investigated.	9252704
Dysplasia, Carcinoma, Ulcerative Colitis, selenium, Acute and chronic inflammation	Altered Intercellular Communication	Atypical mitoses were present in 19.2% (SE 4.7) of the 26 specimens having chronic active inflammation, in 16.9% (SE 5.6) of the 9 with UC in remission, in 34.6% (SE 7.7) in mucosas with dysplasia (n = 8) and in 49.1% (SE 10.2) in carcinoma (n = 16).	9252704
selenium, Dysplasia, Chronic inflammation, Carcinoma	Altered Intercellular Communication	Atypical mitoses were also found in 17.0% (SE 5.4) in the non-dysplastic mucosa from colitic patients having dysplasia or carcinoma elsewhere as well as in 0.96% (SE 0.3) in 14 "noncolitic" controls with chronic inflammation.	9252704
Inflammation	Altered Intercellular Communication	Since the frequency of atypical mitoses in "noncolitic" controls with chronic inflammation was low, it is evident that factors other than chronic inflammation may be involved in the induction of atypical mitoses in colitics.	9252704
Scoliosis, unspecified	Altered Intercellular Communication	Pinealectomy affects the systemic hormonal balance and consistently induces progressive scoliosis in chickens.	9253089
Renal Insufficiency, Rheumatoid Arthritis, Inflammation, Glomerulonephritis	Altered Intercellular Communication	Crescentic glomerulonephritis in patients with rheumatoid arthritis is rare and a possible pathogenetic mechanisms involved in the development of renal dysfunction are discussed with the special reference to immune complex-induced inflammation.	9256031
Paresis, Myositis	Altered Intercellular Communication	The muscle weakness and the increased levels of CK prompted us to examine the muscle biopsy and to perform the electromyography, both of which suggested severe muscle inflammation.	9256610
Inflammation, Hemorrhage	Altered Intercellular Communication	Microscopic examinations of the gallbladder showed hemorrhage and inflammation.	9256643
Inflammation, Experimental Organism Basal Cell Carcinoma	Altered Intercellular Communication	Does inflammation contribute to the eradication of basal cell carcinoma following curettage and electrodesiccation?	9256908
Inflammation, Neoplasms	Altered Intercellular Communication	Among the multiple possibilities that exist to explain why these residual nests do not appear as recurrent tumor more frequently is the theory that inflammation developing after C&D clears residual tumor.	9256908
Inflammation, Neoplasms	Altered Intercellular Communication	To test the hypothesis that inflammation developing after C&D clears residual tumor not mechanically removed by the procedure.	9256908
Inflammation, Neoplasms	Altered Intercellular Communication	For primary BCC < 1 cm, no evidence was found that inflammation occurring over 1 month following C&D clears residual tumor.	9256908
Sepsis, Inflammation, Disease, Meningitis	Altered Intercellular Communication	Both have been measured in serum and cerebrospinal fluid (CSF) as an index of the degree of inflammation in diseases, including sepsis and meningitis.	9257663
Inflammation, Irritation, Congestion	Altered Intercellular Communication	The items were rated on a six-point Likert scale ranging from none to extremely severe and included commonly recorded symptoms of inflammation such as irritation, congestion, and discharge in the skin, eyes, nose, sinus, pharynx, and chest.	9257782
Inflammation, Pulmonary Edema, CTCAE	Altered Intercellular Communication	Pathologic examination revealed massive pulmonary edema without signs of inflammation.	9259058
Pain Distress Question, Inflammation, Babinski Reflex	Altered Intercellular Communication	Spondylitis was diagnosed on the basis of pain, a transient Babinski's sign, and systemic inflammation.	9259791
Typhlitis, Ulcerative Colitis	Altered Intercellular Communication	Patchy cecal inflammation associated with distal ulcerative colitis: a prospective endoscopic study.	9260788
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	It is generally believed that the mucosal inflammation in ulcerative colitis is characterized by a diffuse, continuous involvement starting from the rectum without "skip areas."	9260788
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In so-called "left-sided" ulcerative colitis distal involvement may be accompanied by more proximal areas of inflammation, particularly in the periappendiceal area of the cecum.	9260788
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation was controlled totally in three patients.	9261317
Inflammation, VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)	Altered Intercellular Communication	We report a case of vitiligo notable for a degree and pattern of lymphocytic inflammation.	9261477
Inflammation	Altered Intercellular Communication	Because ESR is sensitive to immunoglobulins and RF, it may measure general severity better than CRP, even though it is a poorer measure of inflammation.	9263138
Inflammation	Altered Intercellular Communication	Modulation of quantities of bone marrow erythroid progenitors during chronic inflammation may be one of the pathogenetic mechanisms leading to ACD.	9263142
Inflammation, Rheumatism, Refractory anemias, Sample Size Calculation, Lung Diseases, Interstitial	Altered Intercellular Communication	Our observations provide preliminary evidence of the appearance of HPP-CFC in the circulation during inflammation of RA, and during that in other rheumatic diseases such as SSc and PM/DM, and of the association of HPP-CFC with interstitial lung disease in patients with RA.	9263144
Inflammation	Altered Intercellular Communication	The regions showed high signal intensity on T 2-weighted images and moderate enhancement on contrast-enhanced T 1-weighted images suggesting the presence of associated inflammation.	9265667
Acute inflammation	Altered Intercellular Communication	However, we could not detect any significant difference between healthy donors' serum levels and those of donors with acute inflammation.	9266008
Ovarian Follicle, Precocious Puberty	Altered Intercellular Communication	Precocious puberty or early onset of puberty associated with elevated luteinising hormone and follicle stimulating hormone concentrations after stimulation with luteinising hormone releasing hormone was found in 13 of 108 (12.0%) patients (age 7-9 years).	9266188
Hormone abnormality	Altered Intercellular Communication	Both hormonal disorders may be the consequence of damage to the hypothalamus or the pituitary gland caused by increased intracerebral pressure or increased mass of cerebrospinal fluid.	9266188
Inflammation, Rheumatoid Arthritis, Anemia, Chronic disease	Altered Intercellular Communication	Availability of iron and degree of inflammation modifies the response to recombinant human erythropoietin when treating anemia of chronic disease in patients with rheumatoid arthritis.	9266623
Refractory anemias, Inflammation	Altered Intercellular Communication	Response to r-HuEPO in RA patients appears to be dependent on availability of iron and on the degree of inflammation.	9266623
Airway structure, ARCN1 gene	Altered Intercellular Communication	Airway inflammation in COPD assessed by sputum levels of interleukin-8.	9266891
Airway structure, ARCN1 gene	Altered Intercellular Communication	To assess the characteristics of airway inflammation in patients with COPD.	9266891
ARCN1 gene, Airway structure	Altered Intercellular Communication	The sputum concentration of IL-8 appeared to be closely associated with the degree of airflow obstruction in patients with COPD and may serve as a marker in evaluating the severity of airway inflammation, which is a risk factor for COPD.	9266891
Residue on Palate	Altered Intercellular Communication	As results, we found an inflammation-independent strong expression of CD36 in oral epithelia with ortho- and parakeratinization, such as the oral side of the gingiva, the hard palate, and the back of the tongue.	9267103
Post-Traumatic Stress Disorder, Pain Distress Question	Altered Intercellular Communication	Results indicate that subtalar arthrodesis is an effective treatment for adult patients with pain and disability secondary to acquired planovalgus, posttraumatic, and inflammatory conditions of the hindfoot.	9269162
Inflammation, Muscle fiber atrophy	Altered Intercellular Communication	All biopsies were characterized by endomysial chronic inflammation, muscle fiber degeneration and regeneration, rimmed vacuoles, and angular atrophic esterase-positive muscle fibers.	9269823
Amyotrophic Lateral Sclerosis, Cessation of life	Altered Intercellular Communication	We conclude that early in ALS, at a time when hand muscle function is normal, corticomotor threshold is reduced and suggest that this may be a manifestation of abnormal excitability of cortical or spinal motoneurons to neurotransmitters, whose action will ultimately lead to cell death.	9270669
PTHLH gene, Squamous cell carcinoma, Hypercalcemia, CTCAE, Malignant Neoplasms	Altered Intercellular Communication	This paper describes humoral hypercalcemia of malignancy (HHM) associated with squamous cell carcinoma (SCC) of the breast and its association with assayed levels of parathyroid hormone related protein (PTHrP).	9271026
Inflammation, Tacca leontopetaloides	Altered Intercellular Communication	Being a sensitive marker of inflammation, our test might reveal the presence of an underlying smoldering inflammation in patients with recurrent TIA.	9272190
Inflammation, Atherosclerosis	Altered Intercellular Communication	These results are in agreement with modern studies that show that inflammation is an important feature of atherosclerosis.	9272190
Inflammation, Neuralgia, Osteoporosis, Pain Distress Question	Altered Intercellular Communication	Neuropathic pain and prolonged regional inflammation as two distinct symptomatological components in complex regional pain syndrome with patchy osteoporosis--a pilot study.	9272813
Pain Distress Question, Inflammation, Complex Regional Pain Syndromes, Osteoporosis, Allodynia, Swelling, Sore to touch, Neuralgia, Chronic Kidney Diseases	Altered Intercellular Communication	Our clinical observations of patients with CRPS associated with patchy osteoporosis suggest that CRPS may have the following two distinct components: (1) neuropathic pain that includes severe spontaneous pain or severe persistent mechanical allodynia and (2) prolonged regional inflammation, the early phase of which could be indicated by positive inflammatory symptoms of pain (tenderness), heat, redness, swelling and loss of function and their alleviation with corticosteroids.	9272813
Airway structure, Inflammation	Altered Intercellular Communication	We conclude that in acute airway inflammation kinins seem to be mainly generated by plasma kallikrein whereas in chronic inflammation, kininogenases other than plasma kallikrein, such as tissue kallikrein, seem to be more important.	9272914
Asthma, Eosinophilic inflammation	Altered Intercellular Communication	However, the extent to which eosinophil inflammation relates to indices of asthma severity in chronic stable asthma is still a matter of debate.	9272923
Sepsis, Liver Dysfunction	Altered Intercellular Communication	Due to liver dysfunction in sepsis, the brain neurotransmitter profile may be deranged.	9273458
Hypertension, CTCAE, Coronary Arteriosclerosis, Chronic Kidney Diseases	Altered Intercellular Communication	High prevalence of myocardial ischemia and vasoconstrictive hormonal release in hypertension during chronic renal failure.	9274841
Epithelial atrophy, Inflammation, Psoriasis, Hyperkeratosis	Altered Intercellular Communication	Other morphologic features were encountered in biopsies of PRP which have received little emphasis in the dermatopathology literature, including epithelial atrophy, significant dermal inflammation, the presence of eosinophils and plasma cells within the inflammatory infiltrates, an abnormal granular cell layer, and epidermolytic hyperkeratosis, albeit none were statistically signficant predictors of PRP over psoriasis.	9274959
Dermatitis, Atopic, allergic inflammation, Data types - Address	Altered Intercellular Communication	Eosinophils (Eo) are known to play a critical role in the chronic allergic inflammation, featuring pathologically in atopic dermatitis (AD), and the Eo percentage in the peripheral blood is elevated in AD infants (0 y) as well as in older AD children (3-15 y).	9277003
Acute inflammation, Eye Infection	Altered Intercellular Communication	To study the efficacy of combined diclofenac 0.1% and gentamicin 0.3% (Digen) eyedrops to treat postoperative inflammation and prevent ocular infection in eyes having phacoemulsification.	9278797
Acute inflammation	Altered Intercellular Communication	Digen was more effective in reducing postoperative inflammation than gentamicin alone (P < .01).	9278797
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	Control of ocular inflammation after cataract extraction with rimexolone 1% ophthalmic suspension.	9278798
Cataract, Intraocular inflammation	Altered Intercellular Communication	To assess the efficacy and safety of rimexolone 1% ophthalmic suspension in controlling intraocular inflammation after cataract extraction.	9278798
Cataract, Inflammation	Altered Intercellular Communication	Laser flare-cell measurement of inflammation after uneventful extracapsular cataract extraction and intraocular lens implantation.	9279671
Cataract, Inflammation, Macular Edema, Cystoid	Altered Intercellular Communication	Effectiveness of diclofenac eyedrops in reducing inflammation and the incidence of cystoid macular edema after cataract surgery.	9279674
Inflammatory abnormality of the eye	Altered Intercellular Communication	The signs of ocular inflammation were greater in the eyes receiving placebo; the difference was particularly evident up to 1 week after surgery.	9279674
Acute inflammation	Altered Intercellular Communication	Cell density was higher in eyes with increased postoperative inflammation.	9279679
Sarcoidosis, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Sarcoidosis is a chronic systemic disease of unknown etiology characterized by non-caseating granulomatous inflammation of various organs.	9280420
Inflammation	Altered Intercellular Communication	It was present in 57% of cases and could also account for some symptoms leading to the removal of appendices with no histopathologic signs of inflammation.	9280889
Acute and chronic inflammation	Altered Intercellular Communication	Chronic and chronic active gastritis-like inflammation were also demonstrated in some cases.	9280889
Inflammation, Gastritis	Altered Intercellular Communication	The identification of chemical gastritis like inflammation, which is often viewed and documented as normal mucosa is also important in this process.	9280889
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Histologic evidence of vasculitis was absent or mild in 92% of cases and histologic evidence of perivascular inflammation was absent or mild in 73% of cases.	9282847
Inflammation, Doxorubicin/Methotrexate/Vinblastine, Vasculitis, CTCAE, Necrosis	Altered Intercellular Communication	The frequency of histologic changes associated with vasculitis, perivascular inflammation, and vessel necrosis varied with the time interval between embolization and AVM resection.	9282847
Inflammation, Hemorrhagic	Altered Intercellular Communication	Embolization of AVMs with silk does not result in marked inflammation or increased hemorrhagic complications as compared with other agents.	9282847
Inflammation, Demyelination, Neoplasms	Altered Intercellular Communication	The MR appearance of an enlarged cord with associated abnormal signal and enhancement is nonspecific and can simulate tumor, demyelination, and inflammation.	9282865
Rupture, Angina, Unstable, Thrombosis, Inflammation, Fissure, Infarction, Fibrous, Dental Plaque	Altered Intercellular Communication	Autopsy studies have shown that unstable angina and infarction are related to plaque instability and involve events such as fissure or rupture of the fibrous cap, thrombosis and inflammation.	9283528
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	HP-infected gastric mucosa was classified according to the degree of inflammation and intestinal metaplasia.	9284831
Interstitial Fibrosis Assessment, Interstitial inflammation, Chronic Kidney Diseases, Atrophy of kidney	Altered Intercellular Communication	Sonographic and pathologic studies show renal atrophy, interstitial fibrosis, and interstitial inflammation, which explain the loss of renal function.	9285152
T-Cell Lymphoma, Inflammation, THM gene, liposarcoma, Neoplasms, Sclerosis, Sarcoma, Squamous cell carcinoma, melanoma, Teratoma, Thymic Cyst, Hodgkin Disease	Altered Intercellular Communication	Of 196 mediastinal FNABs, 22 (11%) were lesions with significant spindle-cell component: granulomatous inflammation (four); benign nerve sheath tumor (four); thymic cyst (two); spindle-cell thymoma (two); large-cell non-Hodgkin's lymphoma with sclerosis (two); nodular sclerosing Hodgkin's disease (two); liposarcoma (two); spindle-cell squamous carcinoma possibly arising in a teratoma (one); unspecified high-grade sarcoma (one); spindle-cell malignant melanoma (one); and nonspecific fibrous tissue (one).	9285187
Inflammation, Atresia of nasolacrimal duct	Altered Intercellular Communication	Tearing and secondary inflammation due to lacrimal duct atresia has to be treated by early dacryocystorhinostomy.	9285221
Cognition Disorders	Altered Intercellular Communication	It is suggested that some of the cognitive deficits associated with MS, which are caused by synaptic disruption of neurotransmitter functions, may be reversed through pulsed applications of picotesla range EMFs.	9285288
Inflammation, Traumatic injury, Neoplasms	Altered Intercellular Communication	Lymphangiectasia resulting from trauma, neoplasm, irradiation, or inflammation characterizes secondary lymphatic obstruction.	9285740
Inflammation, Leukocytosis, Fever, CTCAE	Altered Intercellular Communication	Evidence of inflammation consisted of an elevated sedimentation rate in 76%, leukocytosis in 61% and fever in 61% of individuals.	9286631
Communicable Diseases, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Predisposing factors such as diabetes mellitus, previous nonspinal surgery and other sites of infection or inflammation were identified in 17 (41%) patients and 30 (73%) were older than 50 years.	9286631
Inflammation, CDIPT gene, Back Pain	Altered Intercellular Communication	Increased alertness for PIS in the context of focal back pain with clinical or laboratory signs of inflammation is needed to speed up its detection.	9286631
Periodontal Infection	Altered Intercellular Communication	Effective treatment of periodontal infection and reduction of periodontal inflammation is associated with a reduction in level of glycated hemoglobin.	9287060
Inflammation, Trypanosomiasis	Altered Intercellular Communication	[Blood levels of protein markers of inflammation and nutrition in the meningo-encephalitis phase of human African trypanosomiasis].	9289245
Nephrons, Nephrotic Syndrome	Altered Intercellular Communication	We hypothesized that the increased glomerular permeability to serum proteins in the nephrotic syndrome might lead to alterations of the somatotropic hormone axis, thereby contributing to growth failure and catabolism in the nephrotic state.	9291202
Inflammation, Granuloma, Abscess, Granulomatous inflammation, Granulomatous	Altered Intercellular Communication	The severe inflammatory lesions involved the dermis and the hypodermis and had three main histopathological patterns: (i) granulomatous nodular or diffuse inflammation with mixed granulomas in 57 (80%) of the cases; (ii) prevailing abscesses with mild granulomatous reaction in 28 (15%) of the biopsies; and (iii) deep dermal and subcutaneous granulomatous inflammation with no neutrophil component in three (4%) of cases.	9292069
Allergic, Nasal Polyps, Acute and chronic inflammation	Altered Intercellular Communication	The pathogenetic mechanism of nasal polyps remains unknown, although polyps seem to be an expression of chronic nasal inflammation of both allergic and nonallergic origin.	9292175
Sinusitis, Upper Respiratory Infections	Altered Intercellular Communication	AT patients also require close long-term followup with intense medical management of their chronic respiratory inflammation that appears to put them at increased risk for nonoperative complications of their severe sinusitis.	9292176
Cataract, Inflammation	Altered Intercellular Communication	Flare-cell meter measurement of inflammation after uneventful cataract surgery with intraocular lens implantation.	9292681
Cataract, Inflammation	Altered Intercellular Communication	To determine whether intracapsular intraocular lens (IOL) implantation leads to less anterior chamber inflammation than sulcus implantation in eyes having uneventful extracapsular cataract extraction (ECCE).	9292681
Intraocular inflammation, Hypopyon	Altered Intercellular Communication	He developed severe intraocular inflammation, hypopyon, and dense vitreous membranes 4 days after the enhancement surgery.	9292684
Inflammation, Hydrarthrosis, Hepatitis, Bacterial Infections, infection pyogenic	Altered Intercellular Communication	Findings evaluated as possible factors in the joint inflammation included apatite crystals, iron, lipids, amyloid, and difficult to diagnose nonbacterial infections such as hepatitis C. Some highly inflammatory joint effusions in patients undergoing chronic hemodialysis are not due to pyogenic infections and may be attributable to other factors.	9292804
Inflammation, Calcinosis, Myocardial Infarction	Altered Intercellular Communication	Calcification was dense in the area of severe myocardial necrosis, and the distribution of calcium deposits suggested that the calcification was a consequence of significant inflammation of the myocardium.	9293412
Inflammation, Fibrosis Assessment, Aneurysm	Altered Intercellular Communication	Intramural sarcoma of the carotid artery with adventitial inflammation and fibrosis resembling 'inflammatory aneurysm'.	9293539
Inflammation, Fibrosis Assessment, Aneurysm	Altered Intercellular Communication	A rare case is described of an intramural sarcoma of the right common carotid artery coexisting with adventitial inflammation and fibrosis, resembling 'inflammatory aneurysm', which was resected from a 33-year-old Japanese woman who had presented with a pulsatile mass on the right side of the anterior neck.	9293539
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	The antigranulocyte scan demonstrated an intense inflammation in the latter metastasis.	9293793
Hyperuricemia	Altered Intercellular Communication	It is evident that on the population level hyperuricemia may serve an indicator of hormonal-metabolic athero-, diabetogenic shifts.	9297274
Inflammation, Periodontitis, Osteopenia	Altered Intercellular Communication	Gingival crevicular fluid (GCF) was collected from 18 subjects with adult periodontitis whose clinical findings (gingival inflammation, pocket depth, and bone loss on radiographs) predicted excessive MMP activity in their periodontal pockets.	9297576
Inflammation, Mastocytosis, Squamous metaplasia	Altered Intercellular Communication	We propose that respiratory epithelium is the "native" epithelium of LNC and squamous metaplasia results from inflammation induced stem cell hyperplasia in respiratory epithelium, evidenced by co-expression of "simple" and "stratified-epithelial-type" CK in all cells of transitional-type pseudostratified epithelium, the early stage in metaplastic transformation.	9298101
Inflammation, atherosclerotic	Altered Intercellular Communication	Atherosclerotic plaques contain inflammation, composed largely of macrophages and lymphocytes.	9298683
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	This aspect of inflammation in atherosclerotic lesions has not been investigated.	9298683
Refractory anemias, Inflammation	Altered Intercellular Communication	Furthermore, anti-SLAM mAbs increased the production of IL-10, IFN-gamma, and TNF-alpha by in vitro activated synovial fluid mononuclear cells, supporting the idea that signaling through SLAM may play a role in the regulation of synovial inflammation in patients with RA.	9300723
Inflammation, Urinary Incontinence, Presenile dementia, Edema, Liver Dysfunction, Electrocardiogram abnormal, Anemia, Anorexia, Hypoalbuminemia, Renal Insufficiency, Dyspnea	Altered Intercellular Communication	Data on 13 potentially prognostic factors were analyzed: dementia, being bedridden, anorexia, edema of the lower limbs, urinary incontinence, dyspnea fever, hepatic dysfunction, renal dysfunction, anemia, hypoalbuminemia, inflammation, and electrocardiographic abnormality.	9301265
Inflammation, Urinary Incontinence, Liver Dysfunction, Hypoalbuminemia, Electrocardiogram abnormal, Anorexia	Altered Intercellular Communication	Patients lived longer if they were not bedridden, anorexic, incontinent of urine, hypoalbuminemic, or if they had no inflammation (p < 0.05): being bedridden, anorexia, urinary incontinence, hepatic dysfunction, hypoalbuminemia, inflammation, and electrocardiographic abnormalities.	9301265
Pancreatitis, Cholestasis, Pancreatitis, Alcoholic	Altered Intercellular Communication	In patients with non-alcoholic chronic pancreatitis, with or without associated autoimmune or related diseases, pancreatic inflammation particularly involved the ducts, commonly resulting in duct obstruction and occasionally duct destruction.	9301509
Hypopituitarism, Obesity	Altered Intercellular Communication	Hypopituitarism with growth hormone (GH) deficiency is associated with obesity characterized by central (abdominal) distribution of fat.	9302387
Hepatic inflammation	Altered Intercellular Communication	In severe hepatic inflammation, high numbers of activated cytotoxic T cells were found, along with marked hepatocellular expression of beta 2-microglobulin (beta 2-MG) and intercellular adhesion molecules.	9303509
Hepatic inflammation	Altered Intercellular Communication	By contrast, in mild hepatic inflammation only a few activated T cells were detected, together with a weaker reactivity for all molecules studied.	9303509
Inflammation, Scleroderma	Altered Intercellular Communication	Cranial magnetic resonance examination reaffirms the clinical impression that inflammation is not solely confined to the skin in this form of linear scleroderma.	9303594
Inflammation, Comedone	Altered Intercellular Communication	This has lead us to hypothesize that the chronic inflammation seen in COME is the result of an imbalance in the ratio of proinflammatory cytokines and inhibitors that favors the proinflammatory cytokines.	9305251
Inflammation	Altered Intercellular Communication	The detection, in these patients, of high circulating levels of IL-1 beta and HA is very important from a clinical point of view because they could be considered specific markers of inflammation.	9306222
Granulomatous inflammation, "Duodenal Crohns disease	Altered Intercellular Communication	A histological examination of duodenal mucosal biopsy samples showed granulomatous inflammation, and thus a diagnosis of intrinsic duodenal Crohn's disease was made.	9306611
Intracapsular cataract extraction, Uveitis, Polycystic Ovary Syndrome, Intraocular inflammation	Altered Intercellular Communication	To compare the incidence rate of posterior capsule opacification (PCO) after phacoemulsification and standard extracapsular cataract extraction (P/ECCE) in eyes with antecedent uveitis with the incidence rate in eyes without any history of intraocular inflammation.	9307631
Single organ dysfunction, Vasculitis, Septic Shock	Altered Intercellular Communication	Cytokine-related systemic intravascular inflammation may represent a common pathogenic link between initial insult and multiple organ failure in septic shock patients.	9308320
Osteogenesis, Inflammation, Foreign-Body Reaction	Altered Intercellular Communication	Aseptic inflammation due to formation of ectopic ossification and foreign-body response, following wear of the polyethylene socket, was responsible for false-positive results.	9310035
Infection by Cryptococcus neoformans, Inflammation, Tuberculosis, Actinomycosis, Aspergillosis, Caseous necrosis	Altered Intercellular Communication	Nine patients had a confirmed diagnosis [tuberculosis (n = 1), cryptococcosis (n = 3), actinomycosis (n = 2), and aspergillosis (n = 1)] or a suggestive diagnosis [caseating granulomatous inflammation (n = 1) and caseous necrosis (n = 1)] made after US-guided FNAB.	9311046
Inflammation	Altered Intercellular Communication	Earlier reports in the literature have suggested that a local immune reaction against collagen might play a role in enhancing inflammation, thereby increasing scar formation.	9313121
Acute and chronic inflammation	Altered Intercellular Communication	These findings indicated that the likely cause of calculus formation was chronic scrotal inflammation leading to a disturbance in reabsorption of hydrocele fluid.	9321716
Sepsis	Altered Intercellular Communication	The role of right colectomy in controlling inflammatory conditions and intra-abdominal sepsis remains controversial.	9322662
Post-Traumatic Stress Disorder, Inflammation, Molluscum Contagiosum	Altered Intercellular Communication	To report molluscum contagiosum as a cause of severe posttraumatic intraocular inflammation.	9323953
Intraocular inflammation, Corneoscleral laceration	Altered Intercellular Communication	A 9-year-old girl developed severe intraocular inflammation in the right eye after a corneoscleral laceration.	9323953
Inflammation	Altered Intercellular Communication	It is necessary to pay attention to anaerobic bacteria while treating the patients with chronic pus inflammation of the middle ear.	9324554
allergic inflammation, Respiration Disorders	Altered Intercellular Communication	Very recently, the allergic inflammation has been considered as the crucial event in the pathogenesis of allergic respiratory diseases.	9324698
Inflammation, Disease	Altered Intercellular Communication	As allergic diseases can lead to chronic inflammation, an early and long-lasting treatment is mandatory.	9324698
Inflammation	Altered Intercellular Communication	Moreover, the decrease in antioxidant protective factors is related to inflammation or stature.	9324920
Inflammation, Hepatitis C	Altered Intercellular Communication	These findings indicate that serum levels of these molecules correlated with disease progress in chronic HCV infection, and that IL-10 and IL-15 may reflect the degree of inflammation in the liver.	9328122
Dermatitis	Altered Intercellular Communication	IL-13 over-expression in skin is not confined to IgE-mediated skin inflammation.	9328132
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Different triggers of IL-13 gene expression may influence the diverse patterns of inflammation seen in different inflammatory skin disorders.	9328132
Airway structure, Asthma	Altered Intercellular Communication	We suggest that measurement of exhaled NO may represent a noninvasive method of monitoring airway inflammation in children with asthma.	9329413
Hormone abnormality, Malignant Neoplasms	Altered Intercellular Communication	Patients at risk of having malignancies or hormonal disorders must remain under close surveillance.	9329414
Inflammation, Sample Size Calculation	Altered Intercellular Communication	Serum levels of soluble TNF-RI and RII correlated well with their in situ expression and with clinical and laboratory signs of inflammation and disease progression in patients with SSc.	9330935
Inflammation, Scleroderma , Corneal Endothelial Cell Loss	Altered Intercellular Communication	Our data provide evidence for a central role of the TNF-alpha/TNF-R system in the early pathological events of scleroderma with prominent inflammation and endothelial cell damage.	9330935
Arthritis, Synovial Hypertrophy	Altered Intercellular Communication	Our most prominent finding was that ultrasound is able to exclude joint inflammation; when the ultrasonographic distance of the joint capsule from the bone rim was < 3 mm, there was no synovial hypertrophy or effusion on MRI scans.	9330939
Inflammation	Altered Intercellular Communication	Effusion in the AC joint may reflect inflammation, but may also be a sign of degeneration.	9330939
Inflammation, Tracheobronchial, Necrosis	Altered Intercellular Communication	In the presence of acute inflammation and necrosis of the wall, tracheo-bronchial defects are difficult to manage.	9332910
Inflammation, Necrosis	Altered Intercellular Communication	Shallow mucosa, necrosis and high grade of inflammation were found in the non-contractor group.	9334106
Inflammation, Fibrosis Assessment, Venoocclusive disease	Altered Intercellular Communication	A liver biopsy showed sinusoidal and perivenular fibrosis without inflammation, compatible with chronic venous obstruction.	9334484
Inflammation, Hepatitis C	Altered Intercellular Communication	Inflammatory markers in chronic hepatitis C. To test the hypothesis that inflammation in hepatitis C follows mechanisms common to immune-activated pathways, the distributions of T and B cells, adhesion molecules and transforming growth factor-beta (TGF-beta) were assessed in liver biopsies with chronic inflammation due to hepatitis C (HCV, n = 8) and other causes (non-HCV, n = 10).	9334839
Vascular Diseases, Neuropathy, Nerve Fibers, Unmyelinated, Inflammation	Altered Intercellular Communication	Sural nerve biopsy revealed a severe loss of unmyelinated and thinly myelinated fibres, consistent with a small fibre neuropathy, without evidence of angiopathy or inflammation.	9335019
Inflammation	Altered Intercellular Communication	Synovial inflammation and 9 separate tissue characteristics were graded histologically.	9336422
Inflammation	Altered Intercellular Communication	MRI-determined synovial membrane volumes were correlated with the overall histologic assessment of synovial inflammation (Spearman's sigma = 0.55, P < 0.001), with fibrin deposition, with subsynovial mononuclear and polymorphonuclear leukocyte infiltration (sigma = 0.51-0.59), and less significantly with macroscopic synovitis, vessel proliferation, and granulation tissue formation (sigma = 0.40-0.42).	9336422
Inflammation	Altered Intercellular Communication	The data suggest that IgE levels or a linked genetic parameter may contribute to the mucosal inflammation in the paranasal sinuses.	9338553
Inflammation, Arterial Hypervascularization	Altered Intercellular Communication	Magnetic resonance imaging signal abnormalities reflected inflammation and hypervascularization of the subchondral bone underlying the affected entheses (low signal enhancing after gadolinium and fat saturation on T1 images, high signal on T2 images).	9338928
Inflammatory, Inflammation, Discitis, Arterial Hypervascularization	Altered Intercellular Communication	In addition to showing involvement of the classic spinal entheses, magnetic resonance imaging also demonstrated evidence of inflammation and hypervascularization of the central part of the vertebral endplates and intervertebral disks, confirming that the center of the disk is an enthesis and that inflammatory enthesitis is the mechanism underlying at least some cases of discitis seen in patients with spondylarthropathies.	9338928
Inflammation, Arthritis	Altered Intercellular Communication	Positively birefringent lipid spherules can be found in association with acute, otherwise unexplained arthritis, and may induce synovial inflammation similar to that seen in other types of crystal-induced arthritis.	9339132
Communicable Diseases, Hemorrhage, Laryngeal Nerve Injuries	Altered Intercellular Communication	Complications that arise after thyroid surgery may be associated with infection, hemorrhage, hormonal problems, and laryngeal nerve injury.	9339803
Upper Respiratory Infections	Altered Intercellular Communication	These criteria included at least two positive sputum cultures and presence or absence of the respiratory tract inflammation.	9340058
Lymphangitis, Traumatic injury, Malignant Neoplasms, Congenital Abnormality	Altered Intercellular Communication	Chylothorax is a rare condition which might be caused by trauma of the chest, malignant tumors, congenital malformation, or inflammation of lymphatic nodes.	9340066
Inflammation, Neoplasms	Altered Intercellular Communication	At presentation, there was a firm tumour without signs of inflammation in the right upper lid area.	9340412
Papillary, Inflammation	Altered Intercellular Communication	Histology showed a circumscribed papillary reaction and a chronic non-specific inflammation with few eosinophils and no giant cells.	9340412
Inflammation	Altered Intercellular Communication	It included stripping of the great saphenous vein and extirpation of varicose veins in the area without acute inflammation.	9340796
Inflammation, Primary malignant neoplasm, Tuberculosis, Neoplasms, Carcinoma of lung, Lung Neoplasms	Altered Intercellular Communication	Mean tumor size was 18.1 mm in primary lung cancer (n = 29), 16.2 mm in metastatic lung cancer (n = 13), 16.3 mm in tuberculosis (n = 18), 15.3 mm in nonspecific inflammation (n = 12), 16.7 mm in benign lung tumors (n = 7), 7.5 mm in intrapulmonary lymph node (n = 2), and 19.4 mm in others (n = 5).	9341257
Inflammation, Bursitis, Rheumatoid Arthritis, Chronic pain, Disorder of tendon	Altered Intercellular Communication	In addition, all patients with rheumatoid arthritis had findings compatible with an inflammation of the retrocalcaneal bursa on MR imaging, whereas none of the patients with tendinopathy associated with chronic heel pain had retrocalcaneal bursitis.	9342119
Fibrillation, Inflammation, Herpes zoster disease	Altered Intercellular Communication	In a sample of 40 patients with acute herpes zoster of varying severity, an abnormal electromyogram (EMG) (fibrillation, positive waves, high-frequency discharges) was found in 21 (53%), suggesting extension of inflammation to the anterior horn and/or anterior motor roots.	9342160
Inflammation	Altered Intercellular Communication	The first, inflammation, showed increased signal intensity on T2-weighted images and iso-intensity on T1-weighted images.	9342167
Inflammation	Altered Intercellular Communication	Only first keratoplasties in corneas without severe vascularization or acute inflammation were included.	9342604
Acne, No endocrine abnormalities, Subfertility, Irregular Menstruation, Hirsutism, Polycystic Ovary Syndrome, Disease	Altered Intercellular Communication	Polycystic ovaries are a common disorder associated with menstrual irregularities, subfertility, hirsutism, acne, and a range of endocrine abnormalities, including high concentrations of plasma luteinising hormone (LH) and excessive androgen production.	9343501
Inflammation, Demyelination, Demyelinating Diseases	Altered Intercellular Communication	A possible role of transient virus-BBB interactions in triggering focal inflammation, BBB breakdown and demyelination in some cases of MS and parainfectious demyelinating disease cannot be discounted.	9345442
Inflammation, Carotid Stenosis	Altered Intercellular Communication	Thus inflammation appears to play a role in the pathogenesis of the neurologic symptoms associated with carotid artery stenosis.	9347853
Inflammation	Altered Intercellular Communication	The timing of laparoscopic cholecystectomy should be within 96 h from onset of the inflammation.	9348622
Inflammation	Altered Intercellular Communication	There are limited data regarding its expression in inflammation and scarring of the adult human cornea.	9349157
Herpes Zoster Ophthalmicus, Inflammation, Rosacea keratitis, Bacterial keratitis, Rheumatoid Arthritis, Keratitis, Herpetic, Interstitial keratitis	Altered Intercellular Communication	Penetrating keratoplasty specimens were selected from cases of herpes simplex keratitis, herpes zoster ophthalmicus, rheumatoid arthritis ulceration, bacterial keratitis, rosacea keratitis, interstitial keratitis, and previous surgery so as to encompass varying degrees of active and chronic inflammation and scarring.	9349157
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In pathological corneas, TN2 immunopositivity was localised in and around regions of active inflammation, fibrosis, and neovascularisation.	9349157
Inflammation	Altered Intercellular Communication	TN2 positivity was less in acute inflammation than in active chronic inflammation.	9349157
Inflammation, Fibrosis Assessment, Avascular Necrosis, CTCAE	Altered Intercellular Communication	These results indicate that in the adult human cornea, TN-C expression is induced in regions of inflammation, fibrosis, and neovascularisation, but that expression is absent in mature, avascular scar tissue.	9349157
Inflammation	Altered Intercellular Communication	This suggests a role for this glycoprotein in inflammation, healing, and extracellular matrix reorganisation of the cornea.	9349157
Parkinson Disease	Altered Intercellular Communication	The results may be consistent with an alteration of glutamate neurotransmission in Parkinson's disease.	9349670
Airway structure, Cystic Fibrosis	Altered Intercellular Communication	Lower airway inflammation in infants and young children with cystic fibrosis.	9351622
Airway structure, Fibrosis Assessment	Altered Intercellular Communication	Airway inflammation is an important component of cystic fibrosis (CF) lung disease.	9351622
Airway structure, Communicable Diseases, Respiratory Tract Infections	Altered Intercellular Communication	In newly diagnosed infants with CF, those without infection had BAL profiles comparable with control subjects while those with a lower respiratory infection had evidence of airway inflammation.	9351622
Airway structure, Respiratory Tract Infections	Altered Intercellular Communication	We conclude that airway inflammation follows respiratory infection and, in young children, improves when pathogens are eradicated from the airways.	9351622
Intestinal metaplasia, Inflammation, Gastroesophageal reflux disease	Altered Intercellular Communication	Inflammation and specialized intestinal metaplasia of cardiac mucosa is a manifestation of gastroesophageal reflux disease.	9351720
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	The patients were divided into groups depending on the histologic presence of cardiac epithelium with and without inflammation or associated intestinal metaplasia.	9351720
Inflammation, Chronic liver disease, fibrogenesis	Altered Intercellular Communication	Laminin P1 (pepsin-resistant fragment of laminin) and aminoterminal peptide of type III procollagen are measurable in serum and are now considered useful serum markers of fibrogenesis and inflammation in chronic liver diseases.	9352126
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Furthermore, this protein occurred in all specimens collected from patients suffering from IBD and its quantity reflected the increased severity of inflammation.	9352128
Vitreoretinal Area, Inflammation, Neoplasms, Infection, Tuberculosis, Pulmonary, Traumatic injury, Corneal Diseases, Glaucoma, CTCAE	Altered Intercellular Communication	Histopathological data were divided into eight groups according to the causes leading to enucleation: trauma, phthisis, corneal disease, inflammation, vitreoretinal disease, glaucoma, tumors and infections.	9352274
Inflammation, Neoplasms, Infection, Tuberculosis, Pulmonary, Traumatic injury	Altered Intercellular Communication	The z-test showed there were significantly more enucleations in males for phthisis (p < 5.05), infections (p < 0.01), trauma (p < 0.01) and inflammation (p < 0.01) and more enucleations for tumors in females (p < 0.01).	9352274
Inflammation, Neoplasms, Infection, Tuberculosis, Pulmonary, Retinal Diseases, Traumatic injury, Corneal Diseases, Glaucoma, CTCAE	Altered Intercellular Communication	The primary or underlying causes leading to enucleation were tumors (1185 eyes, 33.8%), phthisis (587 eyes, 16.7), glaucoma (561 eyes, 16.0%), vitreoretinal diseases (320 eyes, 9.1%), infections (259 eyes, 7.4%), corneal disease (229 eyes, 6.5%), trauma (209 eyes, 6.0%) and inflammation (156 eyes, 4.4%).	9352274
Tuberculosis, Pulmonary, Infection, Traumatic injury, Corneal Diseases	Altered Intercellular Communication	Time trends in enucleating eyes with different causes showed the number of enucleations for phthisis, infections, corneal diseases, trauma and inflammations had dropped during the ten-year period 1986-1995 compared to 1976-1985 (z-test, p < 0.01).	9352274
Inflammation	Altered Intercellular Communication	Twenty-seven of the patients had a history of previous urothelial trauma, either by instrumentation or inflammation.	9352688
Inflammation, Angina, Unstable	Altered Intercellular Communication	C-reactive protein, a reactant of the acute phase of inflammation, has been shown to be increased in patients with unstable angina.	9352968
Neuroblastoma, Endocrine System Diseases, Neoplasms	Altered Intercellular Communication	One tumor was associated with the syndrome of inappropriate secretion of antidiuretic hormone, an endocrinopathy we found in three of five case reports of thymic neuroblastoma in adults.	9353092
Neurologic Deficits, Ototoxicity, Aortic Aneurysm, Thoracoabdominal	Altered Intercellular Communication	We investigated whether neurotransmitter excitotoxicity is associated with neurologic deficits after thoracoabdominal aortic aneurysm operations.	9354517
Injury of central nervous system, Ototoxicity	Altered Intercellular Communication	These data suggest that neurotransmitter excitotoxicity plays a significant role in central nervous system injury.	9354517
Inflammation, Structure of otoconia, Fibrosis Assessment, Metaplasia, Atrophic	Altered Intercellular Communication	By far the greatest number of histological factors, namely liths, atrophy, fibrosis, parenchymal inflammation, lymphoid germinal centres, mucous and ciliary metaplasia, salivary extravasation and glycosaminoglycan accumulation, was related to the degree of inflammation, which appears to be of the greatest importance in the aetiology and pathogenesis.	9354894
Inflammation, Fibrosis Assessment, Atrophic	Altered Intercellular Communication	Inflammation, atrophy and fibrosis were related to duration of symptoms, which supports the concept of a chronological progression through increasingly severe histological changes.	9354894
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Effect of inflammation on measures of antioxidant status in patients with non-small cell lung cancer.	9356549
Inflammation, Peritonitis	Altered Intercellular Communication	The dialysate protein concentration progressively increased from no peritonitis to mild and severe inflammation.	9358532
Inflammation, Acute appendicitis NOS (disorder)	Altered Intercellular Communication	Initial clinical examination, laboratory inflammation parameters, and routine ultrasonography (US) were evaluated prospectively in 205 patients admitted for suspected acute appendicitis.	9358775
Asthma, Sinusitis	Altered Intercellular Communication	Inhalation of the airbag contents produced supraglottic and subglottic airway inflammation, resulting in sinusitis and exacerbation of her underlying asthma.	9358786
Inflammation, Chronic vomiting, Dislocations, Perforation of stomach	Altered Intercellular Communication	We observed 19 complications including: dislocation of the duodenal part into the stomach (n = 5); inflammation at the insertion site (n = 3); perforation of the stomach (n = 2), which healed under conservative treatment; disconnection of the retention disk (n = 4); occlusion of the tube (n = 4), and chronic vomiting (n = 1).	9360201
Pneumonitis	Altered Intercellular Communication	The data presented here suggest that human lungs express iNOS mRNA but that the production of iNOS protein may be tightly regulated and is expressed in pulmonary inflammation.	9361997
Crohn Disease, Carcinoid Tumor	Altered Intercellular Communication	The hormonal data of patients treated as Crohn's was indistinguishable from patients with known carcinoid.	9362193
Inflammation, Musculoskeletal Pain	Altered Intercellular Communication	Polymyalgia rheumatica (PMR) has an abrupt onset of inflammatory symptoms, making it a useful model for studying the effects of inflammation in bone.	9365092
Seizures, Hyperreflexia, Spasm	Altered Intercellular Communication	Strychnine competes with the inhibitory neurotransmitter glycine producing an excitatory state characterized clinically by hyperreflexia, severe muscle spasms, and convulsions.	9365429
Airway structure, Asthma	Altered Intercellular Communication	These findings suggest that the eosinophil activation in the airway is closely linked to the symptoms and airflow obstruction of asthma, and that the ECP concentration in induced sputum could serve as useful marker for evaluating the severity of asthma and monitoring airway inflammation to achieve the optimal control of asthma.	9367463
Inflammation, Macular Edema, Cystoid	Altered Intercellular Communication	Efficacy of diclofenac eyedrops in preventing postoperative inflammation and long-term cystoid macular edema.	9368162
Inflammation, Necrosis	Altered Intercellular Communication	The main histopathologic characteristics were necrosis, presence of trophozoites, and acute and/or chronic inflammation.	9369114
Ulcer, Aneurysm, vascular inflammations, Behcet Syndrome, "Dieulafoys vascular malformation	Altered Intercellular Communication	The rare observation of Behcet's syndrome presenting with Dieulafoy's ulcer in our patient raises the question as to whether this type of ulcer, usually caused by a developmental malformation of a submucosal gastric artery, may occasionally be due also to submucosal aneurysms that result from a vascular inflammation.	9370143
Low Back Pain, Inflammation, Urethritis	Altered Intercellular Communication	Urethritis occurred in 27%, eye inflammation in 13%, and low back pain in 44% of the patients.	9370874
Cessation of life, Inflammation, Blood Coagulation Disorders	Altered Intercellular Communication	Predicted mortality, on the basis of GMSPS, laboratory indices of inflammation and coagulopathy, and historical controls, was for between four and eight deaths.	9371168
Airway structure, Bronchitis	Altered Intercellular Communication	Airway inflammation is an important pathologic feature in chronic bronchitis, and we hypothesized that individuals with greater inflammatory responses may be more likely to acquire the disease.	9372657
Bronchitis, Chronic, Inflammation	Altered Intercellular Communication	In conclusion, smokers with chronic sputum production have an increased infiltration of neutrophils and macrophages and an increased proportion of CD8+ T-lymphocytes in their bronchial glands, supporting the important role of bronchial-gland inflammation in the pathogenesis of chronic bronchitis.	9372687
Airway structure, Asthma	Altered Intercellular Communication	In the search for markers of airway inflammation, we investigated the role of soluble interleukin-6 receptor (sIL-6R) in patients with bronchial asthma.	9372694
Inflammation	Altered Intercellular Communication	Thus, serum sIL-6R may reflect inflammation of the airway.	9372694
Inflammation, Tuberculosis, Pulmonary	Altered Intercellular Communication	One patient with late presentation had severe inflammation and had phthisis bulbi develop with no light perception.	9373105
Intraocular inflammation, Sarcoidosis	Altered Intercellular Communication	The ocular manifestations and clinical course of 22 patients with intraocular inflammation compatible with sarcoidosis and elevated ACE level (including 11 patients with abnormal chest radiograph) were compared with those of a group of 18 patients with intraocular inflammation due to biopsy-proven sarcoidosis.	9373478
Intraocular inflammation, Sarcoidosis	Altered Intercellular Communication	These results suggest that intraocular inflammation compatible with sarcoidosis in conjunction with raised ACE levels would be accordant with a diagnosis of sarcoidosis in patients in whom histological diagnosis is either not practical or not possible.	9373478
Inflammation, Asthma	Altered Intercellular Communication	In order to determine whether matrix metalloproteinases (MMPs) contribute to inflammation in asthma, we have examined the release of MMPs in bronchoalveolar lavage (BAL) fluids and their production and regulation by alveolar macrophages (AM), in short-term culture.	9374109
Bronchitis, Chronic, Inflammation, Asthma	Altered Intercellular Communication	BAL was collected from 38 asthmatic subjects (24 untreated and 14 treated with inhaled corticosteroids), 26 healthy nonsmokers, and 18 patients with chronic bronchitis used as a control group for another inflammation.	9374109
Inflammation, Spongiosis	Altered Intercellular Communication	Acute inflammation in conjunction with diffuse parakeratosis and spongiosis were seen with 4 cases.	9374222
Inflammation	Altered Intercellular Communication	The effect of the acute inflammation and associated fungal forms may suggest the need for chronic therapy and merits further study.	9374222
Inflammation, Plasmacytoma, Lymphoma, Malignant Neoplasms	Altered Intercellular Communication	Mean uptake ratios also were not significantly different in patients with normal bone marrow scintigraphy and the primary diagnosis of solid malignant tumors, lymphomas and plasmacytomas, and in patients with focal lesions visible on bone marrow scintigraphy (soft tissue inflammation or cold lesions in the bone marrow but with normal sacroiliac regions).	9374347
Enterocolitis, Inflammation, Acute appendicitis NOS (disorder), Mesenteric Lymphadenitis, Enteritis	Altered Intercellular Communication	Clinical manifestations include enteritis, enterocolitis, acute appendicitis, inflammation of the terminal ileum, and mesenteric adenitis.	9376035
Inflammation, Traumatic, Congenital MeSH qualifier	Altered Intercellular Communication	197 obstructions were congenital, 7 traumatic, 4 results of inflammation, and 2 iatrogenic.	9376699
Inflammation, Infection	Altered Intercellular Communication	In case of therapy-resistant inflammation of the eye we have to exclude general infections because cortisone therapy alone may result in worsening the condition.	9376700
Inflammation, Kidney Failure	Altered Intercellular Communication	It manifests initially as localized inflammation, usually of the lungs, and preceeds to the state of generalisation which can be life-threatening due to renal failure.	9376701
Obesity	Altered Intercellular Communication	Increased fatness and obesity appears to be a post-menarcheal phenomenon probably caused by the hormonal changes leading to and following first menstruation.	9376890
Airway structure, Communicable Diseases, Bronchial Obstruction	Altered Intercellular Communication	The improvement in respiratory symptoms, blood parameters and need for medication leads us to believe that airway inflammation decreases after the infection has been eradicated, in spite of the lack of improvement in bronchial obstruction.	9376938
Inflammation, Synovial Hypertrophy, Joint structure of shoulder region	Altered Intercellular Communication	Both US and MRI revealed effusion in the subacromial-subdeltoid (SA-SD) bursa, biceps tendon sheath (BTS) and glenohumeral (GH) joint, but MRI was more accurate in depicting joint inflammation because of its ability to visualize synovial hypertrophy.	9376998
Sepsis, Inflammation	Altered Intercellular Communication	Multivariate regression modeling for the prediction of inflammation, systemic pressure, and end-organ function in severe sepsis.	9377171
Inflammation, Crohn Disease	Altered Intercellular Communication	The clinical symptoms, which may suggest the maintaining inflammation of the intestinal mucosa were found in 50% of patients examined after surgical procedure because of Crohn's disease.	9377677
Inflammation	Altered Intercellular Communication	It may be one of the causes, which maintain the chronic inflammation of the intestinal mucosa and favour disease recurrence.	9377677
Inflammation, Asthma	Altered Intercellular Communication	Green sputum during relapse in asthma may indicate inflammation that is relevant to prognosis.	9377964
Orthodontic, Inflammation	Altered Intercellular Communication	However, although orthodontic patients exhibited more inflammation, their deteriorated clinical conditions could not be accounted for by the sole presence of Aa in their sulci.	9378831
Gingivitis	Altered Intercellular Communication	In contrast, appliance-free young subjects initially infected with Aa had a higher risk of experiencing more gingival inflammation than subjects without the bacterium during a 3-year observation period.	9378831
Inflammatory abnormality of the eye, Borrelia burgdorferi, Uveitis, Optic Neuritis	Altered Intercellular Communication	To present severe involvements of Borrelia burgdorferi in the etiology of uveitis, optic neuritis and other ocular inflammatory conditions.	9379664
Inflammation	Altered Intercellular Communication	Viral inflammations are often a diagnostic and therapeutic challenge.	9381049
Airway structure	Altered Intercellular Communication	The purpose of the paper is to better characterise changes occurred in nose cytology in a group of 50 subjects affected by chronic inflammation of upper respiratory airway.	9381939
Inflammation, Fibrosis Assessment, Hepatitis C	Altered Intercellular Communication	In chronic HCV infection, active inflammation, fibrosis, and variable circulating HCV-RNA levels may coexist with PNAL, particularly among female nondrinkers.	9382037
Adipose tissue loss, Esophagitis, Tissue Adhesions	Altered Intercellular Communication	One developed reflux, and two were found to have esophageal wall inflammation, loss of tissue planes, and mediastinal adhesions at subsequent myotomy.	9382042
Inflammation	Altered Intercellular Communication	Both the density of H. pylori and the degree of inflammation were scored.	9382051
Inflammation	Altered Intercellular Communication	Statistically significant correlations were observed among apoptotic index, iNOS score, degree of inflammation, and density of H. pylori (p < 0.05).	9382051
Granuloma, Interstitial inflammation	Altered Intercellular Communication	Renal biopsy showed noncaseating granulomas and marked interstitial inflammation.	9382167
Encephalopathy, CTCAE 5.0	Altered Intercellular Communication	Hyperammonemia encephalopathy causes inhibition of the brain neurotransmitters at different levels of the CNS, as well as in the retina.	9382596
Inflammation	Altered Intercellular Communication	Transforming growth factor-beta1 is an important cytokine involved in cell growth and inflammation which has been shown to be inhibitory to hepatic DNA synthesis.	9382963
Hyperventilation, Bronchial Hyperreactivity, Asthma, Bronchitis	Altered Intercellular Communication	Hypoxia, hyperventilation of cold and dry air and physical exertion may worsen asthma or enhance bronchial hyperresponsiveness while a reduction in pollen and pollution may play an important role in reducing bronchial inflammation.	9383820
Inflammation, Myocardial	Altered Intercellular Communication	In addition, measurements of plasma levels of markers of myocardial damage (troponin Ic) and systemic inflammation (interleukin-6, interleukin-10, elastase) were done in 9 patients before and after bypass.	9386706
Cessation of life, Inflammation, Hypoxia	Altered Intercellular Communication	Apoptosis, a form of cell death characterized by DNA fragmentation and minimal inflammation, is induced by intrarenal hypoxia in rats.	9386976
Inflammation, Heel pain	Altered Intercellular Communication	(2) The plantar soft tissue of the painful foot was thickened, indicating the heel pain was due to inflammation in the plantar soft tissue.	9387707
Airway structure, Communicable Diseases	Altered Intercellular Communication	Airway inflammation during infection is associated with increased transudation of serum proteins and increased production of protein by the airway epithelium.	9387961
Neurogenic Inflammation	Altered Intercellular Communication	The occurrence of this phenomenon of neurogenic inflammation in the human airway, however, has not been established.	9389293
Allergic, Neurogenic Inflammation	Altered Intercellular Communication	These results provide in vivo evidence for the occurrence of neurogenic inflammation in the human upper airway with active allergic disease.	9389293
Inflammation	Altered Intercellular Communication	Chronic inflammation induced by bacteria often leads to host-mediated destruction of tissues adjacent to the sites of microbial insult.	9390476
Communicable Diseases, Inflammation	Altered Intercellular Communication	Proinflammatory cytokines play an eminent role in pathophysiology of infection and inflammation.	9390642
Tumor necrosis, Infections, Hospital, Ischemic stroke, Inflammation	Altered Intercellular Communication	We prospectively studied the diagnostic value of determination of concentrations of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), and the 55- and 75-kd soluble TNF receptors (sTNFR-p55 and sTNFR-p75) in detection of nosocomial infections in 52 patients with acute ischemic stroke, as an exemplary high-risk group, and compared these findings to those of conventional inflammatory indicators of inflammation (C-reactive protein and leukocyte count).	9390642
Inflammation, Infection	Altered Intercellular Communication	The data suggest that the proinflammatory cytokine IL-6, in addition to its considerable pathophysiologic importance in systemic inflammation, may be valuable in detection of infections in high-risk patients.	9390642
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Induction of various cytokines and development of severe mucosal inflammation by cagA gene positive Helicobacter pylori strains.	9391240
Inflammation	Altered Intercellular Communication	These findings suggest that the ability to induce cytokines differs among the strains; cagA+ strains induce various kinds of cytokines and may cause severe inflammation, whereas cagA- strains induce IL-8 and IL-1 beta only weakly and may cause only mild inflammation.	9391240
Hemorrhage, Hereditary	Altered Intercellular Communication	Hormonal agents have been reported to decrease bleeding in patients with both hereditary and acquired AVMs.	9391685
Neoplasms	Altered Intercellular Communication	The possibility of an associated neoplasm that could be potentially fatal should be considered whenever a testicular tumor of the adrenogenital syndrome continues to grow despite adequate hormonal treatment.	9392334
Inflammation, Fibrosis Assessment, Lymphoplasmacytic Infiltrate	Altered Intercellular Communication	These glands showed proliferation, and nonspecific inflammation with lymphoplasmacytic infiltration, fibrosis, and destruction.	9392346
Balanitis, Phimosis	Altered Intercellular Communication	Penile inflammation (balanitis) may be more common in circumcised boys; preputial stenosis (phimosis) affects circumcised and intact boys with equal frequency.	9393302
Inflammation	Altered Intercellular Communication	Under light microscopy, the gingival tissue showed evidence of moderate to severe acute and chronic inflammation.	9394381
Inflammation, Aortic Aneurysm, Atherosclerosis	Altered Intercellular Communication	Human aortic aneurysm is commonly characterized by the presence of advanced atherosclerosis associated with variable chronic adventitial inflammation.	9395270
Inflammation	Altered Intercellular Communication	The only case where restricted usage of the VH genes was observed, might have been attributable to severe virally-induced tissue inflammation.	9395274
Inflammation, Submucosal Route of Drug Administration, Necrosis	Altered Intercellular Communication	Examination of autopsy and colonic resection showed luminal kayexalate crystals associated with underlying mucosal necrosis, submucosal edema and transmural inflammation.	9395757
Uremia, Inflammation, Intestinal necrosis	Altered Intercellular Communication	Although occurring in complex clinical settings, the pathological findings provide additional evidence that kayexalate in sorbitol may be associated with intestinal necrosis and inflammation in uremic patients and that this may be a clinically and pathologically under-recognized iatrogenic bowel injury.	9395757
Airway structure	Altered Intercellular Communication	These data indicate that thromboxane A2 may contribute to coughing associated with lymphocytic airway inflammation.	9396248
Inflammation, Hemosiderosis	Altered Intercellular Communication	We suspect that the cause of hemosiderosis was related chronic inflammation of active lupus.	9396374
Communicable Diseases, Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	Endogenous implant infection without extrusion of the gold weight may be distinguished from presumed inflammation due to gold allergy by clinical response to antibiotics in the former and requirements of steroids or removal of the implant in the latter.	9396675
Inflammation, Asthma, Inflammatory disorder	Altered Intercellular Communication	Hospitalization for asthma continues to present a major health problem despite advances in our understanding that asthma is an inflammatory disease of the bronchi and that exposure to specific allergens can induce and worsen this inflammation.	9396981
Intestinal metaplasia, Inflammation, Helicobacter pylori	Altered Intercellular Communication	The following histologic features were graded: acute inflammation, chronic inflammation, lymphoid aggregates, intestinal metaplasia, and quantity of Helicobacter pylori organisms.	9398799
Inflammation, selenium, Gastritis	Altered Intercellular Communication	Receiver operator characteristic analysis gave an area of 0.65 +/- 0.01 SE for endoscopy as a test for gastritis (0.5 = chance, 1 = perfect) as defined by the histologic presence of inflammation.	9398799
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Increased levels of soluble adhesion molecules in the serum of patients with hepatitis C. Correlation with cytokine concentrations and liver inflammation and fibrosis.	9398806
Hepatitis C, Chronic, Hepatitis	Altered Intercellular Communication	Lymphocyte adhesion to endothelium, extravasation, and adhesion to hepatocytes are mediated by adhesion molecules and constitute important steps in the liver inflammation due to chronic hepatitis C (HCV-CH).	9398806
Fibrosis, Liver, Hepatitis	Altered Intercellular Communication	sICAM-1 correlated with liver lobular inflammation whereas sVCAM-1, sCD62E, and IL-8 correlated with liver fibrosis.	9398806
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Measurement of soluble adhesion molecules may be an easy way to follow liver inflammation and fibrosis during HCV-CH.	9398806
Communicable Diseases, Inflammation	Altered Intercellular Communication	No Hp infection was detected in absence of chronic antral inflammation.	9398809
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	Apoptosis occurs in uveitic eyes and may play a regulatory role in limiting ocular inflammation.	9400790
Hypoglycemia	Altered Intercellular Communication	The hypoglycaemia symptom profile, counterregulatory hormonal responses, and cognitive performance at R were also compared.	9400916
Inflammation, septic	Altered Intercellular Communication	Postmortem examination confirmed this diagnosis and revealed acute occlusion of the basilar artery by an infected (septic) thromboembolus showing granulomatous inflammation, which most likely arose from an endocardial vegetation with identical histology.	9401796
Inflammation, Thrombosis, Hemorrhage, Necrosis	Altered Intercellular Communication	(3) Type III: arterial fibrinoid necrosis or transmural inflammation with or without thrombosis, parenchymal necrosis, or hemorrhage.	9402096
Stress Fractures, Nutrition Disorders, Pain Distress Question	Altered Intercellular Communication	The possibility of fatigue fracture should be considered in patients who have pain in the lower extremities that is exacerbated by activity, especially if they have hormonal or nutritional disorders.	9402215
Sinusitis	Altered Intercellular Communication	The imaging finding which supported the diagnosis of acute sinusitis with US was the identification of the hyperechoic posterior antral wall through the hypoechoic inflammation.	9402236
Inflammation	Altered Intercellular Communication	Ninety-six percent of the biopsies revealed severe superficial mucosal inflammation and 89% showed deep inflammation.	9402346
Conjunctivitis	Altered Intercellular Communication	Two patients (two eyes) showed partial success, with surrounding conjunctival inflammation.	9402822
Inflammation	Altered Intercellular Communication	At this threshold, the difference was not related to diagnosis, clinical inflammation or synovial membrane volume, e.g.	9402860
Headache	Altered Intercellular Communication	A central neurogenic mechanism such as a dysregulation of some neurotransmitter system might underlie not only headache but also other coexistent disorders; findings highlight the role of serotonin pathways.	9403366
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is considered to be caused in part by smoking-induced inflammation, but it is unknown which inflammatory cells within the small airways are associated with the obstruction.	9403729
Inflammation, Hematoma, Hemorrhage	Altered Intercellular Communication	Minor complications consisted of arterial puncture (15%), local hematoma (4.4%), local bleeding (3%), and local inflammation (5%).	9403747
Degenerative polyarthritis, anaphylaxis, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	These data suggest that anaphylactic degranulation of mast cells may have occurred to a greater extent in osteoarthritis than in rheumatoid arthritis, despite the relative lack of synovial inflammation in osteoarthritis.	9404229
Inflammation, anaphylaxis, Spondylarthritis, Degenerative polyarthritis, Rheumatoid Arthritis	Altered Intercellular Communication	Although the eosinophil cationic protein detected may not reflect eosinophilic inflammation in the joint, the presence in synovial fluid of tryptase of both major forms, and of histamine, appears to indicate that mast cell products are secreted constitutively, as well as by processes of anaphylactic degranulation in rheumatoid arthritis, seronegative spondyloarthritis and osteoarthritis.	9404229
Inflammation, Psoriasis, Dermatitis, Atopic	Altered Intercellular Communication	This paper deals with the correlation of clinical scoring and serologic markers of inflammation in atopic dermatitis and psoriasis.	9404560
Alzheimers Disease", Parkinsonian Disorders	Altered Intercellular Communication	Levels of the neurotransmitter somatostatin (SS) have previously been shown to be reduced in the cortex and hippocampus of demented parkinsonian patients and patients with Alzheimer's disease.	9406918
Inflammation	Altered Intercellular Communication	The adaptive or pathologic responses of epithelial cells to inflammation are poorly characterized.	9407399
Inflammation	Altered Intercellular Communication	Microscopic evaluation showed morphological changes associated with increased inflammation.	9407399
Inflammation	Altered Intercellular Communication	Whilst the former cell area decreased, the latter increased in specimens with severe inflammation.	9408072
Ulcer, Inflammation, Chronic venous insufficiency	Altered Intercellular Communication	Cutaneous inflammation limited to the region of the ulcer in chronic venous insufficiency.	9409177
Inflammation, CREST Syndrome, fiber, Necrotizing vasculitis	Altered Intercellular Communication	Four sural nerve biopsy specimens from the CREST patients demonstrated multifocal fiber loss and perivascular inflammation; one was diagnostic for necrotizing vasculitis and two others were highly suggestive for necrotizing vasculitis.	9409360
Tic disorder	Altered Intercellular Communication	This emphasizes the role of other neurotransmitter systems in the pathophysiology of tics.	9409371
Acute inflammation	Altered Intercellular Communication	Since increased intraoperative iris irritation can lead to increased postoperative inflammation, we are interested in postoperative reactions to several varied surgical procedures.	9410232
Hyperplasia, Chronic inflammation, Neoplasms	Altered Intercellular Communication	As etiologic factors or fundamental diseases, mainly neoplasms and chronic inflammations with hyperplasia of the oral mucosa and a primary chronic (obstructive) sialadenitis were found, but age-related mechanisms could not be excluded.	9410617
Inflammation, Tooth Loss	Altered Intercellular Communication	Patients with severe disease were found to have a higher rate of tooth loss and an increased rate of gingival inflammation.	9410618
Inflammation, Redness, Edema	Altered Intercellular Communication	In two patients, peri-implant inflammation (microbiologically confirmed Staphylococcus aureus) occurred, which was clinically only determined by soft tissue oedema and rubor.	9410640
Inflammation	Altered Intercellular Communication	Our observations also link the keratinocyte EGF receptor-ligand system to psoriatic inflammation, and suggest that aberrant expression of AR in the epidermis may represent a critical step in the development or propagation of psoriatic lesions.	9410906
Airway structure	Altered Intercellular Communication	A negative relationship was found between the presence of airway inflammation, as indexed by mononuclear cell tissue infiltration, and the density of PGP 9.5-positive nerves in both smooth muscle and glands.	9412581
Inflammation, Thrombosis	Altered Intercellular Communication	Platelet-activating factor (PAF) is a phospholipid with multiple actions that include thrombosis and inflammation.	9412624
Inflammation, Autonomic Dysreflexia, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	Association of autonomic nervous hyperreflexia and systemic inflammation in patients with Crohn's disease and ulcerative colitis.	9413271
Inflammatory Bowel Diseases, Inflammation, Autonomic Dysreflexia	Altered Intercellular Communication	Autonomic hyperreflexia was significantly associated with more severe inflammation and systemic disease in IBD.	9413271
Inflammation, Hyperreflexia	Altered Intercellular Communication	Hyperreflexia may be a response to inflammation or a pathogenetic element that drives mucosal inflammation.	9413271
Data types - Address	Altered Intercellular Communication	These data support the role of estrogen in normal and abnormal brain metabolism and suggest potential hormonal interventions which may reduce or prevent the formation of amyloid deposits occur in AD.	9413580
Inflammation, Fever, CTCAE	Altered Intercellular Communication	In the stent-graft group, four patients showed clinical signs of acute inflammation manifested by fever and local tenderness.	9418198
allergic inflammation, Disease remission	Altered Intercellular Communication	These results suggest that conjunctival mast cells can store a range of multifunctional cytokines and release IL-4 during active disease, which may give them an important role in upregulating allergic inflammation in the conjunctiva.	9420138
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Our results indicate that cagA positivity may influence the circulating PGC levels, probably because it causes a higher grade of mucosal inflammation.	9421118
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	H. pylori eradication in both groups was associated similarly with a decrease of inflammation and activity whereas atrophy and intestinal metaplasia were not affected.	9421123
Inflammation	Altered Intercellular Communication	A positive association was revealed between the decrease of H. pylori score and the decrease of both inflammation and activity scores for antrum as well as corpus biopsies.	9421123
Epithelial Damage, Inflammation	Altered Intercellular Communication	Eradication of H. pylori is associated with disappearance of epithelial damage (inflammation and activity) in antral and corpus mucosa.	9421123
Acute and chronic inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Therefore, f-PSA% was measured in controls and patients suffering from BPH, PCa and chronic prostatic inflammation with t-PSA concentrations up to 20 microg/l using the IMMULITE assays.	9421361
Acute and chronic inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Compared with controls or BPH patients, mean f-PSA% values were reduced in PCa patients and in patients with chronic prostatic inflammation.	9421361
Inflammation, Basal cell hyperplasia, neutrophilic, Esophagitis, Ulceration, CTCAE	Altered Intercellular Communication	All cases showed associated nonspecific features of active esophagitis such as ulceration, neutrophilic and eosinophilic inflammation, basal cell hyperplasia, and elongation of the lamina propria papillae.	9422321
Inflammation, Syphilis, Aortitis Syndrome	Altered Intercellular Communication	The pathological findings of aortic cusps were healed valvulitis without specific inflammation as syphilis or aortitis syndrome.	9423086
Inflammation, Calcinosis, Osseous metaplasia	Altered Intercellular Communication	A range of pathological lesions was seen including calcification, chondroid and osseous metaplasia, neovascularization, inflammation and cholesterol deposition.	9423215
Inflammation, Hemorrhage, Necrosis, Edema, Swelling	Altered Intercellular Communication	Significant changes were observed in the vasa vasorum: swelling and detachment of the endothelium, subendothelial oedema, hyaline change, fibrinoid necrosis of the vessel walls with mononuclear cellular infiltration, accompanied by focal haemorrhages and chronic inflammation in the periadventitial soft tissue.	9425496
Inflammation	Altered Intercellular Communication	This study shows that UDCA modulates inflammation in CF-associated liver disease and indicates improvement of liver morphology during 2 years of treatment.	9425933
Inflammation, Demyelination, MS gene	Altered Intercellular Communication	His clinical features resembled multiple sclerosis, but neuroimaging failed to show evidence of demyelination or inflammation in the brain or the optic nerves.	9427178
Diarrhea, Colitis	Altered Intercellular Communication	It was hypothesized that bismuth subsalicylate would resolve both diarrhea and colonic inflammation in microscopic colitis because it possesses antidiarrheal, antibacterial, and anti-inflammatory properties.	9428215
Inflammation, Ulcer	Altered Intercellular Communication	The risk of upper GI events (inflammation or ulcer of esophagus, stomach, or duodenum) was comparable between patients taking etidronate and the two control groups.	9428828
Edema	Altered Intercellular Communication	D-myo-inositol-1,2,6-trisphosphate (1,2,6-IP3) possesses antiinflammatory properties, such as reduced eicosanoid synthesis and inhibition of inflammation-induced edema.	9428861
Inflammation, Neoplasms	Altered Intercellular Communication	The nature of this lesion is still controversial: some researchers consider it a reactive process arising from chronic inflammation while others regard it as a tumor of presumed synovial cell or monocytic macrophage system origin.	9428920
Gastrointestinal inflammation	Altered Intercellular Communication	There is an accumulation of evidence to suggest that mast cells may play a key role in gastrointestinal inflammation.	9429079
Gastrointestinal inflammation	Altered Intercellular Communication	Our findings suggest that early stages in intestinal inflammation may be reflected in changes in mast cell numbers and in their staining properties, and call for a reappraisal of mast cell heterogeneity in the human intestinal tract.	9429079
Inflammation	Altered Intercellular Communication	Microscopic examination of the debrided tissue showed signs of acute and chronic inflammation.	9430001
Granuloma, Acute inflammation	Altered Intercellular Communication	Histologically, a foreign-body granuloma with acute inflammation was the main component of the lesion.	9430024
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Local inflammation within the coronary arteries is involved in the pathogenesis of acute coronary syndrome.	9430368
Inflammation, atherosclerotic	Altered Intercellular Communication	This contrasts with the pattern of cellular activation seen at sites of local inflammation within atherosclerotic plaques, suggesting that two independent inflammatory processes (local and systemic) may be involved in the pathogenesis of this syndrome.	9430368
Inflammation	Altered Intercellular Communication	Interleukin-8 (IL-8) plays a crucial role in the recruitment and activation of polymorphonucleated leukocytes (PMN) in the site of inflammation.	9430851
Nephritis	Altered Intercellular Communication	It is possible to speculate that the timing and progression of kidney inflammation is mediated by an IL-8 dependent mechanism at least in the case of PN.	9430851
Inflammation, Hyperplasia, Necrosis	Altered Intercellular Communication	In addition to the classical histological features of epidermal hyperplasia, necrosis, ballooning and vesical formation, the lesion also showed florid pseudoneoplastic vascular proliferation and a prominent component of eosinophils in the dermal inflammation.	9431721
Inflammation, Gastritis	Altered Intercellular Communication	In the diagnosis of gastritis (chronic inflammation of any degree), the sensitivity and specificity of frozen sections were 92% and 95%, respectively.	9432339
Inflammation, Testicular Hydrocele	Altered Intercellular Communication	An 18-month-old boy who had bilateral abdominoscrotal hydroceles presented with an acute inflammation of the left hydrocele followed 1 week later by similar spontaneous inflammation of the right side.	9434014
Inflammation, Toxic effect	Altered Intercellular Communication	Local inflammation and antitumour activity were observed, whereas no or only minor systemic toxicity was seen in these patients.	9435874
Inflammation, Dental Plaque	Altered Intercellular Communication	Parameters of dental hygiene in each patient included both a plaque index and a gingival inflammation index.	9436135
Communicable Diseases, Inflammation	Altered Intercellular Communication	Serum C-reactive protein as a marker for infection and inflammation in regular dialysis patients.	9438096
HD Term Type, Inflammation	Altered Intercellular Communication	Seventy-five percent of CAPD patients without evidence of inflammation had CRP levels within the quoted normal range (< 10 mg/l), as compared with only 47% of HD patients also without evidence of overt inflammation (p < 0.001).	9438096
Communicable Diseases, Inflammation	Altered Intercellular Communication	Twenty-four patients with overt inflammation (due mainly to infection) were studied, 22 of whom had CRP levels of > 50 mg/l.	9438096
Inflammation, Necrosis	Altered Intercellular Communication	Furthermore, there were no signs of tissue necrosis or widespread chronic inflammation.	9438119
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In both patients, a small discrete area of chronic inflammation and soft tissue fibrosis was noted adjacent to the screw heads.	9438119
Airway structure, Acromegaly, IL13 gene	Altered Intercellular Communication	Bronchial responsiveness and airway inflammation in patients with nonallergic rhinitis with eosinophilia syndrome.	9438486
Airway structure, Anterior nares	Altered Intercellular Communication	We studied whether patients with NARES had bronchial responsiveness to methacholine and airway inflammation and examined the relationship between these factors.	9438486
Inflammation, Hypersensitivity, Disorder of eye	Altered Intercellular Communication	The pathophysiology of chronic allergic eye disease cannot be explained by type I hypersensitivity alone, and T cell-mediated inflammation has been strongly implicated as a possible additional mechanism.	9438492
Inflammation, Tension Headache, Headache	Altered Intercellular Communication	One hundred consecutive patients, the majority suffering from bilateral chronic tension-type headache, investigated with lumbar puncture, were studied as to age, sex, body mass index, diagnosis, lumbar cerebrospinal fluid pressure, and signs of inflammation in the serum in relation to postlumbar puncture headache.	9439088
Inflammation, Headache	Altered Intercellular Communication	Sex, body mass index, cerebrospinal fluid pressure, and signs of inflammation in the serum were not related to the frequency of postlumbar puncture headache in the present study.	9439088
Inflammation	Altered Intercellular Communication	The inferior division of the left oculomotor nerve in the orbit was markedly enhanced, suggesting inflammation of the inferior division of the oculomotor nerve.	9439373
Vitreous Hemorrhage, Inflammation, Damage	Altered Intercellular Communication	Secondary measures: visual acuity and complications, including choroidal, retinal, and vitreous hemorrhage, inflammation, and scleral damage.	9440171
Inflammation, Colitis	Altered Intercellular Communication	Nitrate-reducing bacteria in diversion colitis: a clue to inflammation?	9440640
Gastrointestinal inflammation	Altered Intercellular Communication	A pathogenic role of nitric oxide has been suggested in acute and chronic intestinal inflammation.	9440640
Communicable Diseases, Inflammation	Altered Intercellular Communication	It could be suggested that nitric oxide synthase might produce a bacterial substrate increasing the growth of bacteria with a high pathogenic potential, creating conditions for chronic inflammation and infection in patients with excluded colon.	9440640
Inflammation, Disorder of the optic nerve, Glaucoma, CTCAE	Altered Intercellular Communication	The sparse presence of COX-2 in glaucomatous tissue probably reflects the lack of inflammation associated with glaucomatous optic neuropathy.	9441697
Inflammation	Altered Intercellular Communication	Histological evidence of neuromuscular changes or inflammation in the internal sphincter was documented.	9441803
Inflammation, Muscular Atrophy	Altered Intercellular Communication	There were no significant differences between the botulinum toxin and control groups with respect to histologic evaluation of neuronal size and number, nerve bundle size and number, inflammation, or muscle atrophy.	9441803
Rathke Cleft Cysts	Altered Intercellular Communication	Although comparatively rare and benign lesions, Rathke's cleft cysts are an important cause of hormonal and visual disturbances.	9442498
Fungal endophthalmitis, Syphilis, Orbital Pseudotumor, Toxoplasmosis, Behcet Syndrome	Altered Intercellular Communication	No viral DNA was detected in the vitreous from 13 patients; all were ultimately diagnosed with toxoplasmosis, syphilis, Behcet disease, fungal endophthalmitis, or idiopathic inflammation.	9442777
Retinal Detachment, Inflammation, Ocular Hypotension	Altered Intercellular Communication	Two painful eyes with marked inflammation, hypotony, and retinal detachment were enucleated.	9442779
Chorioretinal scar, Aspergillus endophthalmitis, Intraocular inflammation	Altered Intercellular Communication	Endogenous Aspergillus endophthalmitis usually has an acute onset of intraocular inflammation and often has a characteristic chorioretinal lesion located in the macula.	9442779
Inflammation, Pancreatitis, Leucocytic infiltrate, Neoplasms, Fibrosis Assessment	Altered Intercellular Communication	Chronic inflammation, including inflammatory infiltration and fibrosis, were found around the pancreatic duct where the stones were present, both within and adjacent to the tumor, suggesting that chronic pancreatitis had been present for a protracted period.	9444549
Inflammation, Epirubicin/Prednisone/Vincristine, Osteopenia	Altered Intercellular Communication	The patient is a 16-year-old Japanese male clinically diagnosed as having generalized EOP with slight gingival inflammation and moderate bone loss.	9444599
Inflammation, Respiratory Failure	Altered Intercellular Communication	Body temperature was 38.9 degrees C. Laboratory tests indicated acute inflammation and he had signs of global respiratory failure.	9445776
Hashimoto Disease, Inflammation, Chronic thyroiditis	Altered Intercellular Communication	Based on findings of high gallium-67 citrate uptake in an enlarged thyroid gland accompanied by severe systemic inflammation including an increase in various cytokines and histology of biopsied specimens indicating typical chronic thyroiditis, a diagnosis of acute exacerbation of Hashimoto's thyroiditis was made.	9447297
Inflammation	Altered Intercellular Communication	However, ultrasonogram results and inflammatory findings (C-reactive protein concentration and erythrocyte sedimentation rate) also indicated the presence of inflammation in the thyroid gland.	9447298
Communicable Diseases, Fracture, Inflammation, Failure (biologic function)	Altered Intercellular Communication	The main outcome measures were final fracture alignment, presence of infection or inflammation, hardware failure, time to union, and the number of operative procedures.	9447512
Allergic, Asthma, allergic inflammation	Altered Intercellular Communication	To study the mechanisms contributing to the recruitment of a selective leukocyte subset in allergic inflammation involving the airways as may occur in asthma, we examined whether allergic exposure induces the expression of cell adhesion molecules (CAMs) on the bronchial endothelium of passively sensitized human bronchi.	9448041
Allergic asthma, allergic inflammation	Altered Intercellular Communication	These observations provide further evidence that leukocyte infiltration into the site of allergic inflammation as occurs in atopic asthma is in part regulated by the expression of ICAM-1, VCAM-1, and E-selectin.	9448041
Inflammation	Altered Intercellular Communication	The subcutaneous fat contained a mild perivascular inflammation and one case revealed focal lobular neutrophilic inflammation.	9449487
Inflammation, Neoplasms, Calculi, Tuberculosis	Altered Intercellular Communication	Inflammatory tumors occurred in 123 (83%) patients, in this number non-specific inflammation caused by calculi occurred in 120 (97.5%) patients and specific inflammations (tuberculosis) in 3 (2.5%) ones.	9454147
Inflammation, Neoplasms, Calculi, Tuberculosis	Altered Intercellular Communication	Inflammatory tumors occurred in 123 (83%) patients, in this number non-specific inflammation caused by calculi occurred in 120 (97.5%) patients and specific inflammations (tuberculosis) in 3 (2.5%) ones.	9454147
Inflammation, Orbital Neoplasms	Altered Intercellular Communication	It should be emphasized that the number of orbit inflammations decreases in subsequent years, whereas occurrence of orbit tumors increases.	9454170
Inflammation, Neoplasms, Calculi, Inflammatory disorder	Altered Intercellular Communication	The most frequent disease was neoplastic tumor located in parotid gland, while the most frequent inflammatory disease was non-specific inflammation caused by a calculus in submandibular gland.	9454217
Inflammation, Inflammatory Myofibroblastic Tumor	Altered Intercellular Communication	Among 180 patients in 97 (54%) cases, the presence of inflammatory tumors were stated: non specific inflammation in 74 (76%) patients and specific inflammation in 23 (24%) patients.	9454222
Neurologic Deficits	Altered Intercellular Communication	In addition, alterations in excitatory amino acid neurotransmission in the basal ganglia contribute to the clinical manifestations of motor dysfunction.	9456178
Sacroiliitis, Inflammation	Altered Intercellular Communication	Supplementary radiological evaluation established the extent of inflammation and diagnosis of sacroiliitis.	9458213
Single organ dysfunction, Inflammation, Septic Shock	Altered Intercellular Communication	IL-10 blood levels are directly related to the severity of inflammation and the development of organ failure in septic shock.	9459114
Psychotic Disorders	Altered Intercellular Communication	A possible relationship to endogenous psychotic disorders and the role of neurotransmitter metabolism are discussed.	9459701
Communicable Diseases, Endophthalmitis, CTCAE, Inflammation	Altered Intercellular Communication	Researchers have recently introduced the term "blebitis" to describe a limited form of bleb-related infection (with infection and inflammation limited to the bleb and the peri-bleb area, with or without anterior chamber involvement) in contrast to the more classic form of endophthalmitis.	9460418
Inflammation, Temporomandibular Joint	Altered Intercellular Communication	In this article, biochemical markers in the synovial fluid (SF) for detecting intraarticular inflammation and early cartilage degradation of the temporomandibular joint (TMJ) disease were examined.	9461144
Inflammation	Altered Intercellular Communication	The diagnosis of chronic inflammation of the bladder is made mainly endoscopically, with obligatory endovesical multifocal biopsy of the bladder followed by histological examination.	9461779
Inflammation, Morning stiffness - joint, Pain Distress Question	Altered Intercellular Communication	The following parameters were measured: (1) Three clinical indices of inflammation--the Ritchie articular index, the duration of morning stiffness, and the number of swollen joints; (2) three measures of pain--pain in the morning, pain in the evening, and pain after chosen activity; (3) haematological and biochemical measures of inflammatory activity; (4) assays for the oxidative modification of proteins and lipids.	9462166
Inflammation	Altered Intercellular Communication	Their median inflammation score had increased from grade 1 before to grade 2 after treatment (p < 0.0001).	9462205
Sepsis, Inflammation	Altered Intercellular Communication	Procalcitonin (PCT), a 116 amino acid propeptide of calcitonin, and interleukin 8 (IL-8), a strong neutrophil activating cytokine, are markers of severe inflammation and sepsis.	9462219
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The PyNPase expression level was higher in stromal cells than in cancer cells and the difference increased with inflammation induced by the immunostimulator OK432.	9464495
Airway structure, Asthma	Altered Intercellular Communication	Some serum activity markers of airways inflammation in difficult-to-control asthma patients.	9465429
Inflammation, Chronic inflammatory disorder	Altered Intercellular Communication	Dietary supplementation with n-3 fatty acids from fish oil alleviates inflammation in various chronic inflammatory disease states.	9466128
Osteochondritis Dissecans	Altered Intercellular Communication	Importantly, alterations in the CNS balance of monoaminergic neurotransmitter systems are probably involved in the pathobiology of OCD.	9466376
Vascular Diseases, Inflammation	Altered Intercellular Communication	DIS presented higher PAI-1 and fibrinogen levels; this observation may take in account the high prevalence of vascular diseases and also occult inflammation, which are known to affect these parameters.	9467427
Inflammation	Altered Intercellular Communication	The elderly subjects were categorized by serum C-reactive protein (CRP) concentration, a marker of systemic inflammation.	9467429
Inflammation	Altered Intercellular Communication	The increase in IL-6 also correlated with increased production of CRP, a marker of inflammation.	9467429
Inflammation	Altered Intercellular Communication	Although limited by the small control group, these data suggest that dysregulation of some inflammatory cytokines occurs with age, but the role of inflammation in aging remains unclear.	9467429
Inflammation, Lesion of brain, Cerebrovascular accident	Altered Intercellular Communication	We have previously demonstrated that brain lesions caused by stroke led to the lateralization of T-cell dependent inflammation.	9467655
Communicable Diseases, Inflammation	Altered Intercellular Communication	This infection results in local inflammation and a modification of gastric mucosal epithelial cell characteristics.	9468099
Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	To further appreciate the activation of epithelial cells in the chronic gastric inflammation associated with H. pylori infection and other types of gastritis without consideration of the grade of gastritis.	9468099
Dyspnea, Inflammation, Myalgia, CTCAE 5	Altered Intercellular Communication	We report a case of a 74 year-old man with biological markers of inflammation, progressive dyspnea and myalgia.	9471150
Inflammation, Toxic effect, Liver cyst	Altered Intercellular Communication	The authors hypothesize that besides hepatoxicity (in cases of marked increase of aminotransferases or in patients without liver cysts) slight increase of transaminases could be due to pericystic inflammation secondary to the marked host's immunitary reaction, and so could be considered as an index of therapeutic effectiveness.	9471639
Alzheimers Disease", Dementia, Vascular	Altered Intercellular Communication	P300 and cerebrospinal fluid neurotransmitter metabolites and amino acids were examined in 10 patients with Alzheimer's disease, 9 patients with vascular dementia and 10 healthy controls.	9472419
Chronicity, Inflammation	Altered Intercellular Communication	We suggest that different local mechanisms governing the balance of T cell/cytokine-mediated inflammation in the anterior segment may underlie clinical differences such as chronicity and response to steroids in these disorders.	9472671
Inflammation, Brain Injuries, Occlusion of artery (disorder)	Altered Intercellular Communication	Ischemic brain injury secondary to an arterial occlusion is characterized by acute local inflammation.	9472890
Osteomyelitis, Chronic multifocal osteomyelitis	Altered Intercellular Communication	Chronic recurrent multifocal osteomyelitis (CRMO) was first described by Giedion in 1972 as a self-limited relapsing noninfectious inflammatory condition usually affecting children and adolescents.	9472913
Inflammation, fibrogenesis	Altered Intercellular Communication	N-terminal procollagen-III peptide (PIIIP) (which is a marker of fibrogenesis and, therefore, of on going inflammation), and type IV collagen (found in basement membrane extracellular matrix), were measured in patients with BA to determine their potential as prognostic markers.	9473113
physiopathological, Epilepsy	Altered Intercellular Communication	Increased excitatory amino acid neurotransmission may play a role in neuronal dysfunction and epilepsy.	9475311
Infantile Spasm, Spasm, Neurotoxicity Syndromes, Meibomian gland dysfunction	Altered Intercellular Communication	Aspartate is an excitatory and neurotoxic neurotransmitter, which might have a role in triggering the spasms and the development of neuronal dysfunctions in the patients with infantile spasms.	9475311
Neurogenic Inflammation	Altered Intercellular Communication	This provides more definitive evidence that neurogenic inflammation can occur in vivo in the human upper airway.	9475863
Asthma, Bronchitis	Altered Intercellular Communication	Our results indicate that bronchial inflammation in SA differs from bronchial inflammation in mild asthma.	9476849
Airway structure, Asthma, Bronchitis	Altered Intercellular Communication	This study shows that airway inflammation in asthma and chronic bronchitis is associated with high levels of active elastase, which may play a role in the pathogenesis of airway remodeling.	9476865
Inflammatory abnormality of the eye	Altered Intercellular Communication	Patients presenting with signs and symptoms of ocular inflammation while receiving latanoprost were noted, and their response to the discontinuation of the drug was recorded.	9479285
Discontinuation (procedure), Dermatitis	Altered Intercellular Communication	The treatment-related discontinuations and complications were related to skin inflammation.	9479297
Intraocular inflammation, Uveitis	Altered Intercellular Communication	With adequate control of intraocular inflammation and its sequelae, the visual prognosis in patients in this age group with uveitis is relatively good.	9479298
Inflammation, Blood Product Pathogen Reduction	Altered Intercellular Communication	The AutoCyte PREP system utilizes the CytoRich method, which combines liquid preservation, selective reduction of blood and inflammation, thin-layer cell dispersion and discrete staining.	9479339
Intraocular inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Our patient initially presented with a painful red eye and a subretinal mass, but without signs of intraocular inflammation or glaucoma.	9479815
deficiency aspects	Altered Intercellular Communication	The incidence of hormonal deficiency associated to midline facial malformations is discussed.	9483602
Communicable Diseases, Inflammation, Fever, CTCAE, Traumatic injury	Altered Intercellular Communication	Fever is an important component of immune response of the organism to various stimulating effects (trauma, infection, inflammation).	9483739
Shock, Inflammation	Altered Intercellular Communication	It can generate response systemic inflammation leading to shock and polyorganic insufficiency.	9483744
Inflammation, Neutrophil Infiltration, Necrosis	Altered Intercellular Communication	H. pylori were detected in higher frequency in lesions showing active inflammation with neutrophil infiltration and necrosis of the mucosa.	9483956
Inflammation, Superficial ulcer, Ulcer	Altered Intercellular Communication	These results suggested that H. pylori causes active inflammation in the gastric rucosa, and that milder inflammation causes reddening or irregularity of the mucosa, whereas severer inflammation causes erosion and ulcer.	9483956
Refractory anemias, Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	Oral administration of cartilage-derived type II collagen (CII) has been shown to ameliorate arthritis in animal models of joint inflammation, and preliminary studies have suggested that this novel therapy is clinically beneficial and safe in patients with rheumatoid arthritis (RA).	9485087
Refractory anemias, Inflammation, Leukemia, Mast-Cell	Altered Intercellular Communication	Although RA frequently occurs in patients with CD3+57+ cell leukaemia, and some CD57+ T cells are likely to be involved in the onset of RA, we suggest that CD57+ T cells may rather suppress inflammation of RA, and other cellular components (e.g.	9486402
Refractory anemias, Inflammation	Altered Intercellular Communication	granulocytes) may govern the severity of the inflammation of RA.	9486402
Dermatitis, Atopic, Inflammatory abnormality of the eye, Data types - Address	Altered Intercellular Communication	In order to know the initial lens changes that accompany atopic dermatitis (AD), 99 patients diagnosed dermatologically to have AD without any or with slight external ocular inflammations and with no habit of rubbing the eyelid due to severe itching were examined opthalmologically.	9486546
Splenic Infarction, Pain Distress Question, thromboembolic, Inflammation	Altered Intercellular Communication	We conclude that splenic infarction must be suspected in patients with known hematologic or thromboembolic conditions who develop left upper quadrant pain and signs of localized or systemic inflammation.	9486895
Acromegaly, Chronic disease	Altered Intercellular Communication	Acromegaly, a chronic disease characterized by an excessive secretion of growth hormone (GH), is not commonly diagnosed timely enough.	9487627
Congenital stationary cone dysfunction	Altered Intercellular Communication	In this condition it is caused by chronic bacterial inflammation as a result of impaired mucociliary clearance in congenital ciliary dysfunction.	9487775
Gingivitis, Dental Plaque	Altered Intercellular Communication	A sonic electric toothbrush (Sonicare) and an oscillating/rotating electric brush (Braun Oral-B) were compared for efficacy in removing supragingival plaque, reducing gingival inflammation, reducing probing pocket depth (Pd) and improving probing attachment levels (PAL) in a 6-month, single-blind clinical trial.	9487838
Papillary, Inflammation	Altered Intercellular Communication	Gingival inflammation was determined by the Papillary Bleeding Score (PBS) of Loesche.	9487838
Stricture of hepatic duct, Inflammation, Calculi, Structure of neck of gallbladder	Altered Intercellular Communication	Impaction of a calculus in gallbladder neck or cystic duct or even in its remnant may produce common hepatic duct stricture by direct mechanical impression or associated inflammation.	9488574
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In another case diagnosed as Mirizzi type II, the operation was converted to an open procedure due to intense inflammation and fibrosis around the area of the Calot's triangle.	9488574
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	The severity and activity of inflammation and the presence of atrophy and intestinal metaplasia in the antrum and body were evaluated and compared with H. pylori status.	9489905
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Inflammation of the stomach was related to H. pylori infection, but CagA-seropositive patients did not have moderate or severe inflammation more often than CagA-seronegative ones.	9489905
Inflammation	Altered Intercellular Communication	2) The distribution of CEA, CA125 and SCC between vaginal fluid and the circulation is affected by pregnancy, inflammation and cancer of the genital tract.	9490096
Inflammation, Electrocardiogram: myocardial infarction (finding), Thromboembolic stroke	Altered Intercellular Communication	Among apparently healthy men, elevated levels of C-reactive protein (CRP), a marker for systemic inflammation, predict risk of myocardial infarction and thromboembolic stroke.	9490235
Inflammation, Thrombosis	Altered Intercellular Communication	These prospective data indicate that among apparently healthy men, baseline levels of CRP predict future risk of developing symptomatic PAD and thus provide further support for the hypothesis that chronic inflammation is important in the pathogenesis of atherothrombosis.	9490235
Inflammation, HGD gene	Altered Intercellular Communication	Microdissection of normal epithelium, epithelium at the site of chronic inflammation, HGD, and CA was performed.	9490271
Inflammation, Neutrophilia (finding)	Altered Intercellular Communication	The most important laboratory parameter for a fast diagnosis is CRP (reactant of acute phase of inflammation, which increases as soon as 6 to 12 hours from the beginning of the illness), and also important is: leukocyte count together with neutrophilia in differential count, which is also shown in our article.	9490371
Inflammation, Lymphoma	Altered Intercellular Communication	These findings suggest the possibility that EBV-transformed B cells proliferated in the focal cytokinemic condition caused by long-standing chronic inflammation of the pleura and give us a clue to the lymphoma genesis of PAPL.	9490566
Airway structure	Altered Intercellular Communication	Cyclosporin A treatment and airways inflammation in corticosteroid-dependent asthma.	9491236
Airway structure, Asthma	Altered Intercellular Communication	It has been shown to be of clinical benefit in patients with corticosteroid-dependent asthma, but there are no data on its in vivo effects on airways inflammation.	9491236
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Duodenal histology revealed inflammation in 155 (74.5%) and H. pylori-like bacterial bodies in 153 (73.5%) of the patients; H. pylori infection in the gastric antrum was diagnosed in 173 (83.1%) of the patients.	9492870
Communicable Diseases, Tube - unit dose, Inflammation	Altered Intercellular Communication	Infection, tube erosion, graft rejection, and graft-related inflammation did not occur.	9493112
Inflammation	Altered Intercellular Communication	We hypothesized that versican is associated with the process of collagen synthesis resulting from chronic inflammation.	9493652
Inflammation	Altered Intercellular Communication	Since alpha1-antitrypsin is important in regulating inflammation within the lung in response to environmental exposures, such abnormalities may be of aetiological importance in this disease.	9493678
Gingivitis	Altered Intercellular Communication	There is a strong correlation between gingival inflammation and clinical and sub-clinical ascorbic acid deficiency.	9495147
Pancreatitis	Altered Intercellular Communication	All patients were subjected to ultrasonography for signs of pancreatic inflammation.	9496522
Sebaceous Adenocarcinoma	Altered Intercellular Communication	Sebaceous carcinoma may masquerade for years as an inflammatory condition.	9499782
Inflammation	Altered Intercellular Communication	41-year-old woman with acute inflammation of external ear was observed in our Department.	9499901
Inflammation	Altered Intercellular Communication	The cause of this inflammation was a foreign body which obliterated the external auditory meatus.	9499901
Hemorrhagic inflammation	Altered Intercellular Communication	[A case of hemorrhagic inflammation of an external acoustic duct].	9499902
Inflammation, Purpura	Altered Intercellular Communication	We report a case a twenty-year-old male with purpura of his limbs, and acute, diffused inflammation of the skin of the external acoustic duct.	9499902
Ear Inflammation	Altered Intercellular Communication	In addition, most polyps had mildly increased lamina propria and intraepithelial neutrophilic and mononuclear inflammation.	9500769
Inflammation, Adenoma	Altered Intercellular Communication	A statistically significant, higher proportion of polyps with tubullovillous or villous architecture, an admixture of normal and dysplastic epithelium at the surface of the polyps, and increased lamina propria mononuclear inflammation was noted in probable IBD-associated polypoid dysplastic lesions compared with those considered to be sporadic adenomas.	9500769
HD Term Type, "Alzheimers Disease", Inflammation	Altered Intercellular Communication	Alzheimer's disease, where inflammation is discussed as a possible primary as well as a secondary pathological mechanism, our observations point to a possible involvement of inflammation in the neurodegenerative process in HD.	9502214
Inflammation, Rheumatoid Arthritis, Vascular insufficiency	Altered Intercellular Communication	Angiogenesis and vascular insufficiency each may support the chronic synovial inflammation of rheumatoid arthritis.	9502411
Sepsis, Fever, CTCAE	Altered Intercellular Communication	Sepsis increased energy expenditure independently of fever, probably through hormonal changes.	9504588
Necrotizing granulomatous inflammation, Leukemic infiltration of skin	Altered Intercellular Communication	This lesion was initially diagnosed as chronic granulomatous inflammation 1 year before the definitive diagnosis of leukemia cutis was made.	9504669
Neoplasms	Altered Intercellular Communication	Hormonal stimulation of proliferating pelvico-gential microvascular dendritic cells appears to play a role in the morphogenesis of both tumors.	9505259
Inflammation, Contracture	Altered Intercellular Communication	This method of surgical treatment resulted in a shorter first stage of inflammation, less risk of complications (dermatogenic contracture, limited mobility in the joints of the fingers and toes, trophoneurotic disturbances) and less influence of injurious factors on the tendon in the process of treatment.	9505385
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The presence of each RNA was correlated with histological features blind to the RNA results; individual histological features of inflammation or fibrosis were scored separately.	9505894
Inflammation, Connective Tissue	Altered Intercellular Communication	Cytokines are signalling glycoproteins mediating acute inflammation, chronic inflammation, and connective tissue destruction.	9506880
Inflammation, Arthritis, Lupus Nephritis	Altered Intercellular Communication	As an alternative to classical immunosuppressants in experimental lupus nephritis, we looked at bindarit, 2-methyl-2-[[1-phenylmethyl)-1H-indazol-3-y1]methoxy]propanoic acid, a novel molecule devoid of immunosuppressive effects, which selectively reduces chronic inflammation in rat adjuvant arthritis.	9507220
Extracapillary hypercellularity, Interstitial inflammation, Proximal tubulopathy	Altered Intercellular Communication	Bindarit significantly limited glomerular hypercellularity, interstitial inflammation and tubular damage.	9507220
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	Elevated SCRP (> 20 mg/liter), which mainly reflected the presence of infection/inflammation and was associated with hypoalbuminemia, was more common in malnourished patients than in patients with normal nutritional status, and also more common in elderly than in younger patients.	9507226
Infection	Altered Intercellular Communication	Although C4 concentrations never increased to detectable levels during infections or inflammations an acute phase reaction was determined each time, as evidenced by increased concentrations of CRP.	9508349
Inflammation, Phase II/III Trial, Carcinoma, Squamous intraepithelial lesion	Altered Intercellular Communication	Of the abnormal smears, 158 (37%) had inflammation, and 65 cases (15.5%) demonstrated abnormal cytology of which 50 (12%) were low grade squamous epithelial lesions (atypia/CINI), and the remaining 15 (3.6%) high grade squamous intra-epithelial lesions (CIN II/III and carcinoma in situ).	9509642
Inflammation, Transverse colon	Altered Intercellular Communication	Surgical treatment was necessary in one patient because of segmental stricture of transverse colon caused by inflammation and adhesion of transverse mesocolon.	9509682
parathyroid hormone secretion, Hyperparathyroidism, Primary, Hypercalcemia, CTCAE, Hypophosphatemia	Altered Intercellular Communication	Primary hyperparathyroidism, characterized by hypersecretion of parathyroid hormone (PTH) leading to hypercalcemia and relative hypophosphatemia, is quite common in the elderly.	9509684
Inflammation	Altered Intercellular Communication	[Structural changes in the collagen fibers of the connective tissue in chronic inflammation in the periodontium].	9511413
Infarction, Inflammation, Uterine Fibroids	Altered Intercellular Communication	The patient finally underwent myomectomy, and a pathology review revealed a cellular leiomyoma associated with massive infarction and acute inflammation.	9513878
Colonic Diseases	Altered Intercellular Communication	Both neoplastic and inflammatory conditions may be associated with elevated values; therefore, it is unlikely that calprotectin can predict specific colonic disorders.	9514426
Refractory anemias, Rheumatoid Arthritis, Chronic inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a state of increased oxidative stress associated with chronic inflammation.	9514872
Refractory anemias, Inflammation	Altered Intercellular Communication	In conclusion, pentosidine levels are significantly higher in plasma and synovial fluid from RA patients and may be useful as a biomarker of chronic inflammation in RA patients.	9514872
Inflammation, Pain Distress Question	Altered Intercellular Communication	Inflammation and pain were alleviated by nonsteroidal anti-inflammatory drugs (NSAIDs) and local TMJ ice massage.	9515431
Inflammation, Tuberculosis	Altered Intercellular Communication	An UV light mimetic agent may be produced in the long history of chronic inflammation in tuberculosis or immunodeficient patients.	9515788
Carcinoid Tumor, Interstitial inflammation, Bone Marrow, Osteogenesis, Interstitial Fibrosis Assessment, Calcinosis	Altered Intercellular Communication	Incidental findings included interstitial fibrosis and scar (55), interstitial inflammation (20), calcification (20), and ossification (11), bone marrow emboli (4), chemodectoma (2), and carcinoid tumorlets (1).	9515839
Inflammation, Intestinal metaplasia of gastric cardia, Infection caused by Helicobacter pylori, Acid reflux	Altered Intercellular Communication	Inflammation and intestinal metaplasia of the gastric cardia: the role of gastroesophageal reflux and H. pylori infection.	9516382
Gastroesophageal reflux disease, Inflammation, Pangastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Whether inflammation of the cardia indicates gastroesophageal reflux disease (GERD) and/or is a manifestation of pangastritis caused by Helicobacter pylori infection is unknown.	9516382
Intestinal metaplasia, Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Endoscopic biopsy specimens from the distal esophagus and cardia, fundus, and antrum were evaluated for inflammation, H. pylori infection, and intestinal metaplasia.	9516382
Gastroesophageal reflux disease, Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Neither the prevalence of H. pylori infection (controls, 48%; GERD, 41%) nor cardia inflammation (controls, 41%; GERD, 40%) differed between groups.	9516382
Gastroesophageal reflux disease, Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	All 11 controls and 22 of 23 patients with GERD (96%) and cardia inflammation had H. pylori infection.	9516382
Intestinal metaplasia, Inflammation, Infection caused by Helicobacter pylori, Gastroesophageal reflux disease	Altered Intercellular Communication	Cardia intestinal metaplasia was more common among controls (22%) than GERD patients (3%; P = 0.01); all had cardia inflammation, 7 had H. pylori infection, and 6 had metaplasia elsewhere in the stomach.	9516382
Gastroesophageal reflux disease, Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The prevalence of cardia inflammation is similar in patients with and without GERD and is associated with H. pylori infection (P < 0.001).	9516382
Intestinal metaplasia, Barrett Esophagus	Altered Intercellular Communication	Cardia intestinal metaplasia is associated with H. pylori-related cardia inflammation (P = 0.01) and intestinal metaplasia elsewhere in the stomach, indicating that it is distinct from Barrett's esophagus.	9516382
Inflammation, Opportunistic Infections, Fibrosis Assessment	Altered Intercellular Communication	The neutrophil-dominated inflammation of the lung in cystic fibrosis (CF) has traditionally been seen as a physiological response to continuous opportunistic infection.	9517587
Biliary Colic, Inflammation, Biliary calculi	Altered Intercellular Communication	Our goal was to characterize biliary lipid composition in patients with the syndrome of chronic biliary pain, absence of gallstones, and inflammation of the gallbladder mucosa (acalculous chronic cholecystitis).	9517653
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Fifteen patients were found to have inflammation and/or fibrosis of the gallbladder at cholecystectomy.	9517653
Inflammation	Altered Intercellular Communication	The latter process could be caused by and/or contribute to mucosal inflammation and would also elevate the cholesterol saturation of bile, increasing the risk for cholesterol gallstone formation.	9517653
Diverticulitis	Altered Intercellular Communication	Acute ileal diverticulitis, although uncommon, should be suspected when the clinical presentation indicates an inflammatory condition of the lower right abdomen.	9517656
Inflammation, Malnutrition	Altered Intercellular Communication	Many researchers have speculated that markers of malnutrition such as albumin, prealbumin, cholesterol, and transferrin are influenced by inflammation.	9520912
Malnutrition, Hypocholesterolemia, Hypoalbuminemia	Altered Intercellular Communication	Inflammation increases the incidence of hypoalbuminemia and hypocholesterolemia, potentially leading to overdiagnosis of malnutrition.	9520912
Inflammation, Malnutrition	Altered Intercellular Communication	In the future, soluble IL-2 receptor levels might be used to correct for the impact of inflammation on these markers of malnutrition.	9520912
Inflammation	Altered Intercellular Communication	Thus, besides clot retraction, a possible role of FXIIIa has also been postulated in inflammation.	9521505
Pancreatitis	Altered Intercellular Communication	In severe cases operative endoscopy cured pancreatic inflammation in 11 cases.	9522095
Congenital macroglossia, Inflammation	Altered Intercellular Communication	The recurrent inflammation tends to change into persisting macroglossia with considerable functional and sensory oral disturbances.	9522567
Glossitis	Altered Intercellular Communication	Knowledge of Schuermann's glossitis, a member of the group of etiologically unclarified lingual inflammations, is important for physicians involved in oral medicine because of its therapeutic and prognostic implications.	9522567
Inflammation, Subdural Effusion	Altered Intercellular Communication	Local elevation of inflammatory cytokines in the subdural space of both CSH and subdural effusion without systemic change suggests the presence of local inflammation in the two diseases.	9522908
Pleurisy, Pleural Effusion, Malignant	Altered Intercellular Communication	Despite clinical concern of a malignant effusion, the combination of cytologic and immunophenotypic examination yielded the correct diagnosis of a nonneoplastic effusion related to underlying pleural inflammation and possibly the administration of G-CSF.	9523139
Crohn Disease, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The results suggest significant cellular immunoreactivity disturbances which may be the result of the persisting intestinal mucosa's inflammation in patients with Crohn's disease being in the remission period.	9523477
Gingivitis	Altered Intercellular Communication	These data suggest that the epithelial cells of the gingival tissue are involved in synthesis and secretion of TXB2, which occurred during the development of gingival inflammation.	9524318
Inflammation	Altered Intercellular Communication	Chronic and progressive inflammation may be facilitated by such ELAM-1 and VCAM-1 expression on newly generated vessels.	9524776
Inflammation, Traumatic injury	Altered Intercellular Communication	The vulnerability of the percutaneous coupling of the BAHA to trauma or inflammation was not a major issue; only 4 implants were lost during the total follow-up of more than 250 years.	9525509
Inflammation, Destruction of tissue	Altered Intercellular Communication	Among these, IL-1 and TNF alpha have been suggested as important in promoting cartilage inflammation and tissue destruction, while IGF I has a protective influence on cartilage structure.	9526176
Gingivitis, Gingival Overgrowth	Altered Intercellular Communication	Patients with higher gingival inflammation scores, those on nifedipine medication for more than 4 years, and males were likely to have an increased tendency for higher incidence and severity of gingival overgrowth.	9526908
Inflammation	Altered Intercellular Communication	In RPP and AP tissues, the staining was sparse in areas of inflammation and leukocytic infiltration.	9526920
Inflammation	Altered Intercellular Communication	Collagen type I and III were almost entirely lost at sites of inflammation.	9526920
Colorectal Neoplasms, Malnutrition, Neoplasms	Altered Intercellular Communication	This altered hormonal milieu may not only contribute to malnutrition, but also promote tumor growth, because previous experimental work suggests that glucagon can cause human colorectal tumor cells to proliferate.	9527062
Inflammatory abnormality of the eye	Altered Intercellular Communication	Selected tests were performed depending on the medical history of the patient and the clinical picture of the ocular inflammation.	9527338
Inflammation, Infection	Altered Intercellular Communication	Both the type of cultured organism and the extent of inflammation are well known prognostic factors for the outcome of these infections.	9527406
Inflammation	Altered Intercellular Communication	Comparison of technetium-99m-MDP, technetium-99m-WBC and technetium-99m-HIG in musculoskeletal inflammation.	9529302
Inflammation, musculoskeletal infection	Altered Intercellular Communication	This study compared three radionuclide techniques in distinguishing musculoskeletal infection from noninfectious inflammation.	9529302
Inflammation, Infection	Altered Intercellular Communication	The "early" radiolabeled leukocytes and "late" Hig scintigraphy allowed the greatest ability to distinguish between infections and noninfectious inflammations (p < 0.011 and p < 0.016) with a sensitivity of 96.6% and 96.5% and specificity of 71% and 100%, respectively.	9529302
Inflammation, Infection	Altered Intercellular Communication	The "early" radioleukocyte scintigraphy allowed us to separate infections from noninfectious inflammations.	9529302
Inflammation, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	Altered Intercellular Communication	Evidence of inflammation was not universal, both in the acute and the chronic inflammatory demyelinating neuropathies.	9529777
Cataract, Inflammation, heparin sodium	Altered Intercellular Communication	Heparin-sodium added to the infusion solution during small incision cataract surgery reduced inflammation in the early postoperative period.	9530599
Brachial Plexus Neuritis	Altered Intercellular Communication	Neuralgic amyotrophy is an inflammatory condition of the nerves of the brachial plexus, the cause of which is unknown.	9531827
Inflammation, Nasal Polyps	Altered Intercellular Communication	The higher u-PA/t-PA ratio in nasal polyps and the higher levels of u-PA, when compared with the findings in other organs affected by inflammation, indicate that u-PA plays a part in the inflammatory events resulting in nasal polyps.	9532638
Refractory anemias, Orchitis	Altered Intercellular Communication	The changes in the secretion of TSH, T4, T3 in patients with RA are caused by this pathological process and those in their SF levels affect the course of articular inflammation.	9532653
Lymphedema	Altered Intercellular Communication	[Diagnostic and prognostic significance of some parameters of nonspecific defense humoral mechanism in patients with lymphedema complicated by erysipelas inflammation].	9532910
Inflammation, Lymphedema, Bacterial Infections	Altered Intercellular Communication	Immunological investigation of 193 patients with uncomplicated lymphedema and lymphedema complicated with erysepalas inflammation registered in the patients with inflammation high levels of antigen-nonspecific circulating immune complexes, beta-lysins, alpha1-antitripsin, serum IgE and IgM in the presence of massive bacterial infection of the limb skin.	9532910
Uterine Cervicitis	Altered Intercellular Communication	Pap smears which were unsatisfactory because they were too thick were also associated with the clinical finding of cervical inflammation.	9534749
Inflammation	Altered Intercellular Communication	As the number and methods of skin resurfacing procedures are increasing, there is a small number of patients that develop a prolonged inflammation during the postoperative period.	9537008
Inflammation, Erythema	Altered Intercellular Communication	We attempted to correlate risk factors for the development of prolonged postpeel erythema (PPPE) and inflammation.	9537008
Mastitis, Inflammation, Lactiferous duct, Pathological Dilatation	Altered Intercellular Communication	Periductal mastitis is a benign mammary duct disease that begins with periductal inflammation and progresses to ductal dilatation with minimal inflammation (ductal ectasia).	9537016
Communicable Diseases, Inflammation, Traumatic injury	Altered Intercellular Communication	Upper eyelid entropion can occur as a consequence of inflammation, infection, trauma or surgery.	9537135
Inflammation	Altered Intercellular Communication	Activation and migration of leukocytes to areas of inflammation are important factors in these immunologic responses.	9537339
Inflammation	Altered Intercellular Communication	Fifty-six percent of patients with CD had acute inflammation, but only 10% of the patients were infected with H pylori.	9537465
Inflammation	Altered Intercellular Communication	Focal acute inflammation was a characteristic of H pylori-negative CD (stomach, 31%; duodenum, 40%), which was much less common in the non-CD group (stomach, 2%; duodenum, 8%).	9537465
Deficient Food Intake	Altered Intercellular Communication	Although the pathophysiology of hormonal alterations has not yet been defined, nutritional deficits have been suggested to play a role.	9537848
Weight Gain, Inflammation	Altered Intercellular Communication	Antituberculous chemotherapy with three drugs brought about a prompt improvement of sytemic signs, weight gain, resolution of pulmonary foci and sedation of biological findings referable to inflammation.	9538425
Inflammation, Brain Injuries	Altered Intercellular Communication	This suggests that inflammation after brain injury may worsen the prognosis and that therapies directed against this inflammation may prove useful.	9539598
Ulcer, Inflammation, Pain Distress Question	Altered Intercellular Communication	At follow-up endoscopy, no ulcers, inflammation, break in the mucosa, or pain were noted.	9540879
Hepatic inflammation, Gastric erosions, Neurologic Dysfunction, Diarrhea, Bothered by Vomiting, Anemia, Nausea, Shock, Burn of esophagus	Altered Intercellular Communication	He experienced severe nausea and vomiting within 30 minutes of the ingestion but had no further sequelae such as diarrhea, gastric erosions, esophageal burns, shock, neurologic dysfunction, symptoms of anemia, or hepatic inflammation.	9541053
Vasculitis, Inflammation, Abnormality of the vasculature, Necrosis	Altered Intercellular Communication	The presence and extent of the following vascular abnormalities was assessed: (1) hyalinization/fibrosis, (2) microaneurysm formation, (3) chronic (especially lymphocytic) inflammation, (4) perivascular multinucleated giant cells/granulomatous angiitis, (5) macrophages/histiocytes within the vessel wall, (6) vessel wall calcification, (7) fibrinoid necrosis, and (8) mural or occlusive thrombi.	9542588
Myositis	Altered Intercellular Communication	Biopsy of these targeted muscles demonstrated characteristic histopathologic signs of muscle inflammation in 9 out of 13 patients.	9542783
Hidradenitis Suppurativa, Inflammation	Altered Intercellular Communication	Hidradenitis suppurativa is a chronic suppurative inflammation of skin areas containing apocrine glands: the skin of the axillae, of the breasts and of the anogenital region.	9542883
Nasal Polyps, Sinusitis	Altered Intercellular Communication	Both cyclo-oxygenase enzymes are expressed in normal human upper respiratory epithelium and are not upregulated in chronic sinusitis nor in nasal polyposis, possibly suggesting that Cox products do not have an important role as mediators of the chronic upper airway inflammation.	9543076
Gingivitis, Dental Plaque, Gingival Hemorrhage	Altered Intercellular Communication	Plaque index was 28.5% at baseline and 32.9% at follow-up, indicating a good standard of oral hygiene, and gingival bleeding 31.7% and 24.9%, respectively, suggesting a low to moderate level of gingival inflammation.	9543189
Inflammation, Periodontitis, Calculi	Altered Intercellular Communication	Gingival inflammation and subgingival calculus as determinants of disease progression in early-onset periodontitis.	9543194
Gingivitis, Periodontitis	Altered Intercellular Communication	This study was undertaken to test the hypothesis that gingival inflammation and dental calculus are important determinants of the development and progression of early-onset periodontitis.	9543194
Inflammation, Attachment (action), Calculi, Epirubicin/Prednisone/Vincristine	Altered Intercellular Communication	The association between gingival inflammation and subgingival calculus and the development and progression of attachment loss during the study period in the generalized and the localized EOP groups was significantly higher than the association in the incidental EOP group.	9543194
Inflammation, Periodontitis, Calculi	Altered Intercellular Communication	The results suggest a significant association between gingival inflammation and subgingival calculus and the development and progression of early-onset periodontitis.	9543194
Inflammation	Altered Intercellular Communication	Reactive oxygen species play an important role in promoting inflammation.	9543282
Tolosa-Hunt Syndrome, Cranial nerve diseases, Orbital Pseudotumor	Altered Intercellular Communication	Recurrent cranial neuropathy as a clinical presentation of idiopathic inflammation of the dura mater: a possible relationship to Tolosa-Hunt syndrome and cranial pachymeningitis.	9543331
Tolosa-Hunt Syndrome, Inflammation, Idiopathic Neuropathy, Disease	Altered Intercellular Communication	We discuss the relationship of the idiopathic recurrent cranial neuropathy with disorders characterized by inflammation of the dura mater, such as Tolosa-Hunt syndrome and cranial pachymeningitis.	9543331
Granulomatous inflammation, Granulomatosis with polyangiitis, Vasculitis, CTCAE, Hemorrhagic gastritis	Altered Intercellular Communication	These findings suggest that c-ANCA could play an important pathogenetic role in Wegener's granulomatosis which showed dual pathologic processes: vasculitis and granulomatous inflammation manifested radiographically as either nodular or pneumonia-like lesions, whereas p-ANCA was more often associated with patchy fluffy lung lesions as the consequence of hemorrhagic capillaritis.	9543586
Granulomatous inflammation, Necrotizing vasculitis, Necrosis	Altered Intercellular Communication	Major histologic findings included parenchymal necrosis, necrotizing vasculitis, and granulomatous inflammations.	9543586
Inflammation, Cornea, Ophthalmoplegia, Muscle hypertrophy	Altered Intercellular Communication	The treatment was rapidly efficient, mostly on patient self-assessment, soft tissue inflammation, ophthalmoplegia, corneal involvement, visual acuity and extraocular muscle enlargement on OCT. Post-treatment ophthalmic index was significantly improved (6.75 +/- 3.06 vs. 2.5 +/- 1.41: p < 0.05).	9543692
Granulomatous inflammation, Ulcer	Altered Intercellular Communication	The histological examination of the biopsies taken from these ulcers indicated granulomatous inflammation.	9545843
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	The muscle biopsy demonstrates mononuclear cell inflammation and vacuolated muscle fibers containing paired helical filaments and 6- to 10-nm fibrils, both resembling those of Alzheimer disease brain and Congo red positivity.	9546349
Inflammation, Autosomal recessive inheritance, Hereditary, Autosomal Dominant Disorder, Myopathy	Altered Intercellular Communication	The term hereditary inclusion-body myopathies (h-IBMs) designates autosomal-recessive or autosomal-dominant disorders with muscle biopsies cytopathologically similar to s-IBM but without inflammation.	9546349
Intraocular inflammation, Acquired (qualifier value), Traumatic injury	Altered Intercellular Communication	Acquired cysts may be due to trauma or other forms of intraocular inflammation.	9547797
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	No significant relationship was found between the severity of fibrosis or liver inflammation and the HCV (sub)types.	9548265
Inflammation, Aneurysm, Mycotic	Altered Intercellular Communication	The usefulness of computed tomographic (CT) scans to determine the presence of PAU or surrounding inflammation should be borne in mind even when a small mycotic aneurysm exists.	9548320
Inflammation, Cholestasis, Extrahepatic	Altered Intercellular Communication	The etiology of the extrahepatic portal obstruction in our patient was most likely due to either repeated inflammation or adhesion at the hepatic hilus.	9548328
Inherited Neuropathy, Inflammation, Guillain-Barre Syndrome, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating, Inflammatory neuropathy	Altered Intercellular Communication	Since it is suggested that macrophages play a central pathogenetic role in inflammatory neuropathies, we investigated the expression of macrophage differentiation antigens associated with acute (MRP14 and 27E10 antigens) and more chronic inflammation (MRP8 and 25F9 antigens) in 76 sural nerve biopsies from patients with Guillain-Barre syndrome, chronic inflammatory demyelinating polyneuropathy, other inflammatory neuropathies, hereditary neuropathies and normal sural nerves.	9549523
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	It has been suggested that inflammation may be a possible cause of Alzheimer's disease (AD).	9550286
Inflammation, Hemorrhage, Blood Clot	Altered Intercellular Communication	Other findings include hyalinization of vessel walls, fibrin thrombi, red blood cell extravasation, hemosiderin deposition, and acute and chronic inflammation.	9550313
Abscess in epidural space of cervical spine, Inflammation, Osteomyelitis of vertebra	Altered Intercellular Communication	Magnetic resonance imaging (MRI) demonstrated high cervical epidural abscess with massive soft tissue inflammation and vertebral osteomyelitis.	9550597
Inflammation, Thrombophilia, Dyslipidemias, Chronic Kidney Diseases	Altered Intercellular Communication	Factor VII coagulant activity (VIIc) and hypercoagulability in chronic renal disease and dialysis: relationship with dyslipidaemia, inflammation, and factor VII genotype.	9550647
Inflammation, Dermatitis, Eczema	Altered Intercellular Communication	Our hypothesis is therefore, that galvanization with tapwater iontophoresis interrupts the neurogenic inflammation and prolongs the relapse-free interval in hyperhidrotic palmoplantar eczema (dermatitis).	9551332
Inflammation	Altered Intercellular Communication	Interleukin-8 released from synovial cells may be an important factor to induce acute inflammation in DRA.	9551411
Communicable Diseases, allergic inflammation	Altered Intercellular Communication	We suggest that the immune response to chronic C. pneumoniae infection may interact with allergic inflammation to increase asthma symptoms.	9551736
Communicable Diseases, Inflammation	Altered Intercellular Communication	The study revealed that 42.5% (34/80) of the visit/sites demonstrated an absence of inflammation; 23.7% (19/80) of visit/sites demonstrated slight redness; 13.8% (11/80) demonstrated peri-implant red and moist tissues; 6.2% (5/80) demonstrated granulation tissue associated with the implants; and 13.8% (11/80) infection of the peri-implant soft tissues was noted.	9553884
Prostate carcinoma	Altered Intercellular Communication	Ratio of free-to-total prostate specific antigen in serum cannot distinguish patients with prostate cancer from those with chronic inflammation of the prostate.	9554361
Inflammation, Prostate carcinoma, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	We demonstrate the effect of chronic inflammation of the prostate on the ratio of free-to-total prostate specific antigen (PSA) in serum calculated as a percentage of free PSA and, therefore, that percentage of free PSA is an unspecific means to distinguish among prostate cancer, chronic prostatitis and benign prostatic hyperplasia (BPH).	9554361
Inflammation, Gammopathy, Nephrotic Syndrome	Altered Intercellular Communication	Analysis of serum from patients with inter alia inflammation, nephrotic syndrome, or polyclonal gammopathy showed that clinical information obtained by CZE is comparable with information obtained by AGE and CAE.	9554485
Inflammation	Altered Intercellular Communication	Biopsy samples of gastric and distal duodenum mucous showed an active process of chronic inflammation with a predominance of eosinophils in the lamina propria.	9555622
Nutritional Deficiency, Inflammation, Hyperplasia, Ischemia	Altered Intercellular Communication	Compressions caused by hyperplastic nodules, inflammation, hormones, nutritional deficiency, or systemic or local ischemia, are all possible factors in the pathogenesis of PA.	9556422
Nutritional Deficiency, Inflammation, Hyperplasia, Ischemia	Altered Intercellular Communication	Compressions caused by hyperplastic nodules, inflammation, hormones, nutritional deficiency, or systemic or local ischemia, are all possible factors in the pathogenesis of PA.	9556422
Necrotizing granulomatous inflammation, Prostate	Altered Intercellular Communication	Currettage biopsy of the prostate demonstrated chronic granulomatous inflammation with Langerhan's giant cells, but without TB bacilli.	9556950
Inflammation, Acne	Altered Intercellular Communication	Acne patients demonstrate marked increases in this organism which generates inflammation through a variety of mechanisms.	9557227
Cystitis, Eosinophilic cystitis	Altered Intercellular Communication	Eosinophilic cystitis (EC) is a rare form of bladder inflammation characterized by massive eosinophilic infiltration of the bladder wall.	9557506
Inflammation, Inflammatory disorder	Altered Intercellular Communication	The occurrence of a secondary SS in a variety of inflammatory diseases suggests that salivary gland involvement in these conditions results from as yet unidentified shared pathogenic mechanisms resulting in nonspecific inflammation in this location.	9558175
Communicable Diseases, Inflammation	Altered Intercellular Communication	These observations suggest that stressful conditions related to inflammation, independently of infection, rapidly dampened the reactivity of circulating PMN.	9558403
Acute inflammation, Ulcer	Altered Intercellular Communication	Biopsy specimens of the ulcer revealed acute inflammation but no malignant involvement.	9559038
Clostridium difficile, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Antibiotics suppress normal gut flora, allowing overgrowth of acquired or native Clostridium difficile, with release of toxins that cause mucosal inflammation.	9559631
Brain Injuries	Altered Intercellular Communication	In brain injury, a lucid interval can be followed by secondary neurologic deterioration due to a loss of high-energy metabolites, a release of neurotransmitters, and an increase in intracellular Ca2+.	9559768
Encephalitis, Trauma, Nervous System	Altered Intercellular Communication	Our observations suggest that exicitotoxic neurotransmission may play an important role in the series of events that lead to neuronal damage in encephalitis.	9559919
Migraine Disorders	Altered Intercellular Communication	These results show that high concentrations of neurotransmitter amino acids occur normally in migraine patients and suggest that this profile may be a contributory factor in migraine attacks.	9559996
Inflammation, Abscess	Altered Intercellular Communication	Two of them cause no trouble, the other two manifest from early childhood with inflammation, recurrences with abscesses.	9560984
Inflammation, Fever, CTCAE, Chest Pain, Arthralgia, Have Shortness of Breath question, Anxiety, CTCAE 3.0, cardiac symptom	Altered Intercellular Communication	On average, > 60% patients associated the AMI with cardiac symptoms (chest pain, shortness of breath) or with psychological symptoms, such as anxiety; an important minority (30%) associated it with joint pain or a fever, suggesting inflammation as a possible trigger event.	9561883
Cessation of life	Altered Intercellular Communication	This type of cell death is thought to play a major role and might be linked to specific changes in signal transduction mechanisms in response to hormonal withdrawal.	9563141
Inflammation, Fracture	Altered Intercellular Communication	Primary actinomycotic inflammation of the mandible was diagnosed in nine patients, secondary in six patients (following fracture or resection of the mandible).	9563597
Airway structure, Asthma	Altered Intercellular Communication	Inducing sputum using hypertonic saline is a noninvasive method to investigate airway inflammation in people with asthma.	9563729
Inflammation	Altered Intercellular Communication	The laboratory investigations provided no evidence of inflammation but revealed primary hyperparathyreoidism.	9564241
Retinitis	Altered Intercellular Communication	This study sought to determine the findings of retinal inflammation on gadolinium-enhanced turbo fluid-attenuated inversion recovery (tFLAIR) images.	9564699
Inflammation, Limbal stem cell deficiency	Altered Intercellular Communication	For total limbal deficiency, additional ALT is needed, and AMT helps reconstruct the perilimbal stroma, with reduced inflammation and vascularization, which collectively may enhance the success of ALT.	9565039
Acute inflammation	Altered Intercellular Communication	There were no postoperative complications, and all eyes experienced minimal postoperative inflammation.	9565041
Acute inflammation	Altered Intercellular Communication	The 2 eyes that underwent secondary IOL implantation achieved their best-corrected aphakic visual acuities but experienced a prolonged course of postoperative inflammation.	9565041
Ocular histoplasmosis syndrome, Inflammation	Altered Intercellular Communication	Active inflammation has not been traditionally associated with the ocular histoplasmosis syndrome.	9565044
Inflammation	Altered Intercellular Communication	Leukotrienes and prostaglandines are important mediators of inflammation.	9566100
Inflammation, senile, Data types - Address	Altered Intercellular Communication	The association of immune proteins and immune-competent microglial cells with senile plaques (SP) in both AD and normal aging suggests that these drugs may be able to modify the course of AD, either by interfering with SP formation or by suppressing the inflammation associated with SP.	9566383
Inflammation, Necrosis	Altered Intercellular Communication	However, all false positive cultures represented easily identifiable contaminants, and eight of nine cases had no associated acute inflammation or necrosis.	9568128
Inflammation, Necrosis	Altered Intercellular Communication	In lung FNA specimens, culture and special stains should be restricted to specimens with acute inflammation or necrosis.	9568128
Autoimmune Diseases, Inflammation, Arthritis	Altered Intercellular Communication	Nitric oxide (NO) is a ubiquitous molecule that has been associated with inflammation, arthritis, autoimmune disease, bone resorption, and other biological processes.	9570074
Granulomatous inflammation, Squamous cell carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Only one case was diagnosed confidently as metastatic squamous cell carcinoma with an extensive granulomatous response; the other five were interpreted as "atypical" with descriptive cytology and a differential diagnoses including granulomatous inflammation, in addition to a caveat of "cannot exclude malignancy."	9570210
Inflammation, Neoplasms	Altered Intercellular Communication	We thus conclude that BFP is a urinary nonspecific marker for inflammation or tumor.	9574448
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	These findings suggest that plasma C3 and C4 values are not sufficient to discriminate IgE inflammation (positive prick test) and pseudoallergy (negative prick test) in the assessment of subjects with clinically suspected allergy.	9575333
Inflammation, Bronchitis	Altered Intercellular Communication	Chronic bronchitis is characterized by multidirectional shifts in LPO in the inflammation focus and CEA.	9575586
Inflammation, Chlamydia, Arthropathy	Altered Intercellular Communication	Of the 33 patients 12 (36%) had joint disorders associated with pathogens (bacteria, Mycoplasma/Ureaplasma, Chlamydia) present at the site of inflammation.	9576384
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	The histological severity of inflammation, activity, atrophy, and intestinal metaplasia was assessed according to the Updated Sydney System.	9576449
Cataract, Inflammation	Altered Intercellular Communication	Cytokines may play role in the inflammation process after extracapsular cataract extraction.	9577113
Inflammation, Carcinogenesis	Altered Intercellular Communication	Gastric carcinogenesis is a multifactorial, multistep process, in which chronic inflammation plays a major role.	9577340
Inflammation	Altered Intercellular Communication	There are high levels of S-IgA in human pancreatic juice following chronic inflammation and a protective role is suggested for this immunoglobulin.	9577355
Intestinal metaplasia, Inflammation, Atrophic, epithelium regeneration	Altered Intercellular Communication	Chronic inflammation, polymorph activity, surface epithelial degeneration, atrophy, and intestinal metaplasia were all significantly more severe in the cagA+ than in the cagA- group, whereas only corpus epithelial degeneration was significantly more severe in the vacA s1 group compared with the vacA s2 group.	9577374
Affection	Altered Intercellular Communication	DLBD is characterized neurochemically by severe affection of multiple neurotransmitters networks.	9577669
Inflammation, Fever, CTCAE, Hypothermia due to exposure	Altered Intercellular Communication	Fever and hypothermia: two adaptive thermoregulatory responses to systemic inflammation.	9578327
Inflammation, Fever, CTCAE, Hypothermia due to exposure	Altered Intercellular Communication	Entering both the old dispute (whether fever is adaptive or maladaptive) and its more recent modification (whether hypothermia is protective or detrimental in systemic inflammation), we suggest a new solution.	9578327
Inflammation, Fever, CTCAE, Hypothermia due to exposure	Altered Intercellular Communication	We hypothesize that fever and hypothermia represent two different strategies of fighting systemic inflammation, each developed as an adaptive response to certain conditions, and each beneficial under these conditions.	9578327
Inflammation, Fever, CTCAE, Hypothermia due to exposure	Altered Intercellular Communication	The two thermoregulatory responses represent two complementary strategies of survival in systemic inflammation: fever ensures the active attack against the pathogen; hypothermia secures the defense of the host's vital systems.	9578327
Tissue damage, Inflammation	Altered Intercellular Communication	The pathogenesis of the condition could not be determined but may have been related to the administration of a parenteral corticosteroid preparation, the stress of capture or tissue damage and inflammation.	9578758
Jaundice, Obstructive	Altered Intercellular Communication	Human obstructive jaundice is associated with an important alteration in the hormonal mechanisms of water and sodium regulation.	9580150
Inflammation, Autoimmune Thyroid Disease Pathway	Altered Intercellular Communication	We hypothesize that the acrosyringium might be the target for the inflammation and that PPP is linked to autoimmune thyroid disease and smoking.	9580788
Inflammation, Neoplasms	Altered Intercellular Communication	Focal FDG accumulation in the pancreas with standardized uptake values ranging from 3.4 to 11.2 on FDG PET was ultimately found to be related to inflammation rather than neoplasm.	9580859
Pancreatic Neoplasm, Inflammation	Altered Intercellular Communication	Inflammation can give rise to focal FDG uptake in the same intensity range as pancreatic neoplasm, even when clinical, laboratory and computed tomographic findings suggestive of an inflammatory etiology are equivocal or absent.	9580859
Inflammation	Altered Intercellular Communication	Lobular inflammation was reduced in 9/14 ribavirin-treated (64%) and 3 of 14 IFN-alpha-treated patients (21%; P=.05), each of whom had a biochemical response.	9581698
Inflammation	Altered Intercellular Communication	Since a mildly acidic environment together with increased Zn2+ and Cu2+ are common features of inflammation, we propose that Abeta aggregation by these factors may be a response to local injury.	9582309
Inflammation, Dental Plaque, Dental caries	Altered Intercellular Communication	Correlating Streptococcus mutans counts in saliva with plaque amount, gingival inflammation and caries experience in school children.	9582684
Inflammation, Dental Plaque	Altered Intercellular Communication	There was no association between counts' of S. mutans in saliva with plaque amount and gingival inflammation.	9582684
Inflammation, Abscess, Ulcer, Lung Diseases, Interstitial, Osteomyelitis, Damage	Altered Intercellular Communication	Chronic inflammation (CI) was studied immunologically and immunomorphologically on biopsy and surgical material: interstitial pulmonary diseases, chronic inflammatory processes of the uteri and ovaries, decubitus in the spinal cord damage, trophic ulcers of the limbs, osteomyelitis, chronic abscesses of soft tissues, coccygeal cysts and chronic paraproctitis.	9582987
Calcified (qualifier), Inflammation, Neoplasms	Altered Intercellular Communication	Histologically, the tumor was characterized by a variable cellularity and was composed of bland spindle-shaped cells loosely dispersed in a fibromyxoid to densely fibrous stroma in which calcifications and chronic inflammation were not observed.	9584325
Inflammation	Altered Intercellular Communication	We identified a subset of patients with evidence of superficial clinical infection/inflammation, where the magnitude and duration of the response to surgery was different from the main group.	9586251
Inflammation	Altered Intercellular Communication	Markers of inflammation in crevicular fluid from peri-implant mucosa surrounding single crystal sapphire implants.	9586454
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver biopsy specimens also were analyzed for the presence of fat, inflammation, and fibrosis and graded similarly.	9586705
Infarction, Aneurysmal, Inflammation	Altered Intercellular Communication	MRI/MRA demonstrated changes of stent-graft morphology, aortic neck- and aneurysmal diameter, stent-graft blood flow, stent-graft leakage, blood flow in lumbar arteries, intra-aneurysmal thrombus, periaortic inflammation and vertebral body infarction.	9587333
Hyperglycemia, Diabetes Mellitus, Insulin-Dependent, Inflammation	Altered Intercellular Communication	The pathogenesis is still obscure and includes the hypothesis of extracellular accumulation, secondary to prolonged hyperglycemia in IDDM, production of alternated non-enzymatic glycosylated end products with neoantigen formation, B cell predominant inflammation with autoimmune response against neoantigens and cytokine release secondary to the autoimmune response.	9587750
Inflammation, Communicable Diseases, Blood Clot, Pannus, Tears body substance, Calcinosis	Altered Intercellular Communication	Nevertheless, this nonglutaraldehyde-preserved photofixed pericardial tissue from valves suffering design-related cuspal tears to two years postoperatively remained without significant degradation, inflammation, infection, thrombus, pannus or calcification.	9587858
Inflammatory abnormality of the eye	Altered Intercellular Communication	There was no significant difference in ocular inflammation and complication rates between the 2 groups.	9589728
Abnormal	Altered Intercellular Communication	Abnormal thirst regulation, hormonal derangements, and social, cultural, and psychological habits may account for low compliance with fluid and salt restrictions.	9590193
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	The changes in FAs of the ileal reservoir, which closely resemble those found in human and experimental IBD, probably represent a common pattern of intestinal inflammation.	9590424
Inflammatory abnormality of the eye	Altered Intercellular Communication	The clinical signs of ocular inflammation were recorded on days 1, 3, 8, 15 and 17 or 18.	9590590
Inflammation, Anemia, Abdominal Pain	Altered Intercellular Communication	A 71-year-old woman was admitted for lower abdominal pain with severe inflammation and anemia.	9590709
Inflammation, Meningitis	Altered Intercellular Communication	In acute phase of meningitis correlations between CSF concentration of TNF-alpha and IL-1 beta and other indexes of inflammation in CSF: pleocytosis, concentration of protein and glucose were found.	9591299
Inflammation, Inflammatory Myofibroblastic Tumor	Altered Intercellular Communication	Among 328 patients the presence of inflammatory tumors have been stated in 220 (67.1%) cases, non-specific inflammation in 194 (88.2%) patients and specific inflammation in 26 (11.8%) patients.	9591419
Mycosis Fungoides, Mucinosis, Follicular	Altered Intercellular Communication	Follicular mucinosis is often associated with mycosis fungoides and has been rarely observed to occur with other neoplastic and inflammatory conditions.	9591790
Inflammation	Altered Intercellular Communication	By comparison of the glandular function with the pathology of the gland, it shows that the reduction of glandular function is associated with the severity of grandular inflammation.	9592284
Inflammation	Altered Intercellular Communication	When function index is normal, grandular inflammation is in the Stage I or II, while it decreases or zero, grandular inflammation is in the Stage III or IV.	9592284
Inflammation	Altered Intercellular Communication	Glandular function index may predict the severity of grandular inflammation.	9592284
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Histologically a chronic granulomatous inflammation was revealed in the biopsy of the orbital mass.	9592747
Necrotizing granulomatous inflammation, Sarcoidosis, Granulomatous disorder	Altered Intercellular Communication	Granulomatous orbital inflammation without any local cause or other systemic granulomatous disease strongly suggests a systemic sarcoidosis.	9592747
ER-overload response, Joint structure of shoulder region	Altered Intercellular Communication	Ultrasound examination revealed glenohumeral joint inflammation in 61% (8 out of 13) of the patients with PMR and 63.2% (12 out of 19) of the patients with EORA.	9592862
Inflammation, ER-overload response	Altered Intercellular Communication	These findings suggest that a subgroup of patients with PMR and EORA suffers from shoulder joint inflammation and this synovitis/bursitis/intraarticular effusion might play an important role in the understanding of their symptoms.	9592862
Inflammation, Dilated Cardiomyopathy Pathway, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Two ISFC task forces have just recently clarified in consensus conferences the immunohistopathological criteria for chronic myocarditis or dilated cardiomyopathy with inflammation (DCMi: > 14 lymphocytes or macrophages/mm3) and set standards for molecular and virological diagnoses in endomyocardial biopsies.	9594528
Communicable Diseases, Inflammation, Neuroendocrine Tumors	Altered Intercellular Communication	In-111 pentetreotide uptake is not specific for neuroendocrine tumors because somatostatin receptors are also expressed by white blood cells, leading to the in vivo visualization sites of infection sites or active inflammation.	9596154
Inflammation, Mitochondrial abnormalities	Altered Intercellular Communication	There was no consistent correlation between the mitochondrial abnormalities and markers of muscle regeneration, inflammation, or microscopically detectable pathological alterations of myonuclei in the same fibers.	9596410
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	It may therefore reflect several aspects involved in cardiovascular diseases, including the effects of classic risk factors, hemostatic disturbances, and inflammation.	9598836
Inflammation, Inflammatory abnormality of the eye	Altered Intercellular Communication	Control of inflammation may have a role in the treatment of idiopathic choroidal granulomas and some choroidal neovascular membranes secondary to ocular inflammation.	9599367
senile	Altered Intercellular Communication	Dystrophic neurites of senile plaques are defective in proteins involved in exocytosis and neurotransmission.	9600213
Primary malignant neoplasm, Chronic inflammation	Altered Intercellular Communication	Early rectal cancer associated with chronic inflammation should be considered if a nonpolypoid adenomatous lesion is detected in a patient who has received pelvic radiation.	9600363
Inflammation	Altered Intercellular Communication	Our results suggest that the high load of HTLV-I in patients with HAM may potentially induce systemic inflammation in several organs.	9600686
HD Term Type, Huntington Disease	Altered Intercellular Communication	Loss of neurotransmitter receptors, especially glutamate and dopamine receptors, is one of the pathologic hallmarks of brains of patients with Huntington disease (HD).	9600992
Inflammation, Hypergammaglobulinemia, Anemia	Altered Intercellular Communication	Investigations revealed anaemia, hypergammaglobulinaemia, elevated non-specific indices of inflammation, a reduced Schirmer's test value, lymphocytic infiltration and some atrophy of the parotid gland.	9601239
Inflammation, Fibrosis Assessment, Allodynia	Altered Intercellular Communication	There was a significant correlation between allodynia and signs of marked inflammation, but not between allodynia and neural and perineural cell infiltrates or fibrosis.	9602229
Intraocular inflammation, Uveitis	Altered Intercellular Communication	Testing for EBV does not have to be included in the routine management of patients with uveitis, since indications for an important role of this virus were not found in the pathogenesis of intraocular inflammation.	9602620
Tissue damage, Inflammation	Altered Intercellular Communication	The findings suggest that eosinophil granule proteins may participate in tissue damage in acute phase of inflammation in OCP.	9602632
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	Synovial tissues collected from rheumatoid patients undergoing total joint arthroplasty express markers for acute inflammation.	9603033
Autoimmune Diseases, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis is an autoimmune disease that causes inflammation mainly in synovial tissues.	9603033
Inflammation	Altered Intercellular Communication	The cells types found in the synovium are capable of secreting cytokines which are capable of both acute inflammation (IL-1, IL-6, IL-8, MCP-1 and TNF), as well as chronic inflammation (IL-2, IL-10, and IL-4).	9603033
Inflammation	Altered Intercellular Communication	T-cell derived chronic inflammation cytokines (IL-2, IL-4 and IL-10) were rarely detected.	9603033
Scleritis	Altered Intercellular Communication	A 27-year-old woman with peripheral thinning of her left cornea associated with adjacent conjunctival and episcleral inflammation was clinically examined.	9603393
Inflammatory abnormality of the eye	Altered Intercellular Communication	Administration of sulfones was effective for reducing both skin and ocular inflammation.	9603393
Inflammation, Swelling, Disease, Joint tenderness	Altered Intercellular Communication	Serial clinical examinations comprised ratings of joint tenderness and swelling, and blood drawn during exams was analyzed for sedimentation rate (an indicator of systemic inflammation) and soluble interleukin-2 receptors (a marker of immune system activation known to correlate with RA disease activity).	9603691
Arthralgia, Arthritis	Altered Intercellular Communication	Across-person analyses failed to establish links from daily event stressors to either disease activity or composites of joint pain and joint inflammation when associations were adjusted for the effect of neuroticism on self-report measures.	9603691
Arthritis	Altered Intercellular Communication	At the same time, increased daily stressors were indirectly associated with decreased joint inflammation through reduction in levels of soluble interleukin-2 receptors.	9603691
Pain Distress Question, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	The dual-pathway model, which may be limited to short-term psychological and psychoimmunologic processes, underscores the importance of distinguishing potentially opposing effects of stress on pain versus inflammation in individuals with rheumatoid arthritis.	9603691
Atrial Fibrillation by ECG Finding, Congestive heart failure	Altered Intercellular Communication	Comparison of plasma neurohormones in congestive heart failure patients with atrial fibrillation versus patients with sinus rhythm.	9604948
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	We sought definitive evidence of an antigen-driven B cell response (i.e., clones derived from the same VH, DH, and JH gene segments with shared somatic mutations) in RA synovial mRNA transcripts, and to characterize CDR3 intervals at the target of inflammation in this autoimmune disease.	9606177
Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Hypersensitivity	Altered Intercellular Communication	Leukocytoclastic vasculitis is one category of drug hypersensitivity reactions characterized by distinctive patterns of perivascular inflammation.	9606474
Inflammation, Primary malignant neoplasm, Atherosclerosis	Altered Intercellular Communication	Cell surface adhesion molecule expression is likely to be important in inflammation, atherosclerosis and cancer, and soluble forms of many of these molecules are present in plasma.	9607125
Inflammation, Tuberculosis	Altered Intercellular Communication	The patient had an erythrocyte sedimentation rate of 108 mm/h, images of active tuberculosis in both apical pulmonary lobes and a chronic tuberculous inflammation with caseation and epithelioid tubercles was observed in a biopsy of the anal lesion.	9609040
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The subepidermal acrosyringial zone and the eccrine ducts were associated with lymphocytic inflammation and fibrosis.	9609142
Inflammation, Dental Plaque, Periodontal Route of Administration	Altered Intercellular Communication	In conclusion, 5-to 6-year-old direct composite additions have a negative influence on marginal periodontal health, which consisted of increased plaque retention, gingival inflammation, and periodontal destruction.	9609371
Inflammation, Dental Plaque	Altered Intercellular Communication	These findings indicated that the presence of T. denticola and unidentified spirochetes in health-associated plaque was associated with increased susceptibility to gingival inflammation.	9609381
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Chronic inflammation and elastin degradation in abdominal aortic aneurysm disease: an immunohistochemical and electron microscopic study.	9610343
APP gene, Inflammation, Aortic Aneurysm, Abdominal, Communicable Diseases	Altered Intercellular Communication	To investigate (i) elastin degradation and the possible association between proteolysis and inflammation in abdominal aortic aneurysm disease (AAA), and (ii) the presence of cytomegalovirus (CMV) infection in the walls of AAA.	9610343
Inflammation	Altered Intercellular Communication	The chronic inflammation and degradation of elastin in AAA suggests a possible immune-mediated mechanism.	9610343
Inflammation	Altered Intercellular Communication	The inflammation may be induced by the chemotactic properties of elastin-derived peptides.	9610343
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	C-reactive protein (CRP) is a sensitive marker of inflammation, and elevated levels have been associated with future risk of myocardial infarction (MI).	9610529
prostatitis	Altered Intercellular Communication	Of 158 cases with negative biopsies, 43 (23.2%) had histologically verified prostatic inflammation.	9610567
prostatitis	Altered Intercellular Communication	Prostatic inflammation was a confounding factor for the inadequate specificity of DRE, TRUS and PSAD.	9610567
Stomatitis, Inflammation	Altered Intercellular Communication	Disinfection caused some reduction of the mucosal inflammation under the denture base, but could not completely remove stomatitis during the 4-week test period.	9610859
Inflammation, Liver damage	Altered Intercellular Communication	The authors prove the predominance of free-radical processes in the mechanisms of cellular injury initiated by inflammation mediators and proteolytic enzymes.	9612048
Communicable Diseases, Inflammation, Pain Distress Question	Altered Intercellular Communication	At the time of retrieval, percussion-induced pain was experienced at 4/8 implants, but no macroscopical signs of inflammation or infection or infection was observed.	9612140
Inflammation, Arthralgia, Myalgia, Trigeminal Neuralgia, Dentin Sensitivity, Hemangioma	Altered Intercellular Communication	The disorders included temperomandibular joint pain, trigeminal neuralgia, muscular pain, aphatae, inflammation, and tooth hypersensitivity both postoperatively and in small hemangiomas.	9612167
Inflammation, Erosion lesion, Infection caused by Helicobacter pylori, Cyst of testis	Altered Intercellular Communication	The correlation was established between the degree of Helicobacter pylori infection in the polyp mucous membrane on the one hand, and epithelial and stromal reactions (immuno-inflammatory reaction of stroma, chronic inflammation, formation of Russel bodies, cystes and chronic erosions) on the other.	9612504
Edema of eyelid, Inflammation	Altered Intercellular Communication	The authors present the clinical and histopathological findings in a 71-year-old woman who had previously undergone breast reconstruction with a silicone gel-filled elastomer envelope-type breast implant and who developed severe chronic eyelid edema and inflammation.	9612809
Inflammation	Altered Intercellular Communication	The presence of silicon-containing material within areas of eyelid inflammation supports a role for silicon in the pathogenesis of this patient's condition.	9612809
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Since increasing evidence indicates that neuropeptides play a key role in the regulation of gastrointestinal immune function, the aims of this study were: a) to determine tissue and plasma levels of Vasoactive Intestinal Polypeptide, Substance P, and Calcitonin Gene-Related Peptide in patients with ulcerative colitis, and b) to ascertain whether a relationship exists between tissue concentrations of neuropeptides and the histological grading of mucosal inflammation.	9615269
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Both Vasoactive Intestinal Polypeptide and Substance P concentrations were found to be significantly reduced in endoscopic biopsy specimens of patients with ulcerative colitis compared to controls (p < 0.01 and p = 0.05, respectively), and the reduction appeared to be related to the degree of mucosal inflammation; in contrast, Calcitonin Gene-Related Peptide tissue levels were unchanged.	9615269
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Taken together, our results suggest that the reduction of Vasoactive Intestinal Polypeptide and Substance P is probably a secondary phenomenon, correlated with the degree of mucosal inflammation; whatever the mechanism, the decreased availability of these neuropeptides in the local microenvironment may play an important role in the pathogenesis of ulcerative colitis, by affecting many components of the normal immune response.	9615269
Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis is a chronic inflammatory condition characterized by an altered intestinal immunoinflammatory response.	9615269
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Abnormally low plasma cysteine and cystine levels were associated with inflammation in IBD (p < 10(-4)).	9616308
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Decreased rGSH levels were demonstrated in non-inflamed mucosa (p < 0.01) and inflamed mucosa (p = 10(-6)) in patients with IBD, while GSSG increased with inflammation (p = 0.007) compared with controls.	9616308
Thrombosis, Arteritis, Granulomatosis with polyangiitis	Altered Intercellular Communication	Coronary artery inflammation and thrombosis in Wegener's granulomatosis-polyarteritis nodosa overlap syndrome.	9616852
Inflammation, Atherosclerosis, Necrotizing Arteritis, Coronary Thrombosis	Altered Intercellular Communication	We report an extreme example of how intimal inflammation in multiple sites of a coronary tree with and without atherosclerosis may trigger coronary thrombosis, in an elderly female patient who died of a clinically unrecognized systemic autoimmune-inflammatory disorder with necrotizing arteritis.	9616852
Inflammation	Altered Intercellular Communication	Although there were no clinical signs of heart involvement, the coronary tree showed inflammation associated with multiple mural and occlusive thrombi.	9616852
Cholecystitis	Altered Intercellular Communication	In our opinion, the many terms used (cholecystitis glandularis proliferans, hypertrophic, adenomyomatosis) to define those conditions are not appropriate for our case but rather for the gallbladder's chronic inflammation characterized by the Rokitansky-Ashoff sinuses.	9617120
Arthralgia, Pain Distress Question, Inflammation	Altered Intercellular Communication	In our opinion arthrocentesis is a method of simple application, well accepted by patients, leading to a clear improvement of symptoms, as far as pain relieving effect and functionality are concerned, thanks to the possibility to drain by washing the constituents of the inflammation and the mediators of pain; this method may be applied routinely, as therapeutic support, in those patients with clinical histories of condilo-meniscal uncoordination and presenting limitations in the opening of the mouth and articular pains.	9617127
Airway structure, Asthma	Altered Intercellular Communication	[Eosinophil count in induced sputum samples as a marker of airway inflammation and adequacy of corticosteroid inhalation treatment in asthmatic patients].	9617140
Airway structure, Asthma, Eosinophilic disorder	Altered Intercellular Communication	Airway inflammation still persists in many well-controlled chronic asthmatic patients, and induced sputum eosinophilia predicts an early decrease of PEF after reduction of inhaled corticosteroids.	9617140
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Biopsy specimens of colonic mucosa obtained from 26 patients with active UC and 21 patients with inactive UC were studied in order to clarify the relationships among the inflammation factors in UC.	9617859
Inflammation, Central hypothyroidism	Altered Intercellular Communication	The present case showed that inflammation in the cavernous sinus could be one of the causes of TSH deficiency.	9617867
Inflammation, Diffuse panbronchiolitis, Bronchiolitis, Recurrent sinopulmonary infections	Altered Intercellular Communication	Diffuse panbronchiolitis (DPB) is a distinct clinicopathologic entity, which is characterized by chronic recurrent sinopulmonary infection and inflammation.	9617876
Inflammation, Vitreous opacities	Altered Intercellular Communication	The cases were characterized by moderate or no inflammation in the anterior ocular segment and by the presence of vitreous opacity and fundus lesions.	9619028
Airway structure, Asthma	Altered Intercellular Communication	Chronic airway inflammation, one of the pathophysiologic features of bronchial asthma, is suspected to be responsible for irreversible pathological changes of airways, called airway remodeling.	9620926
Proctitis, Inflammation, Granulomatous	Altered Intercellular Communication	Lectitis purulenta et granulomatosa (granulomatous purulent nail bed inflammation).	9621149
Inflammation, Granulomatous	Altered Intercellular Communication	A granulomatous purulent nail bed inflammation of the great toenails in a 69-year-old female patient is described.	9621149
Inflammation, Pseudomonas aeruginosa	Altered Intercellular Communication	The inflammation was most often caused by Pseudomonas aeruginosa (32%), cocci (33.6%), and fungi (14.1%).	9621813
Inflammation	Altered Intercellular Communication	The cumulative risk of ileal resection at ten years due to new inflammation was significantly (p < 0.01) higher in the case of ileocolic/ileorectal anastomosis than of ileostomy (38% vs. 11%).	9622892
Cataract, Inflammation	Altered Intercellular Communication	We attempted to illustrate connections between selected metabolic parameters and the inflammation course in patients after cataract operations.	9623256
Inflammation, Granuloma	Altered Intercellular Communication	The histologic specimen revealed a severe ileal inflammation with cosinophilia and the colon specimens epitheloid microgranuloma.	9623333
Inflammation	Altered Intercellular Communication	Histopathology showed aggregates of yeast elements between corneal stromal lamellae, without inflammation.	9625567
Pericarditis, CTCAE, Myocarditis	Altered Intercellular Communication	The most troublesome complication of acute pericarditis is recurrent episodes of pericardial inflammation, occurring in 15% to 32% of cases.	9626180
Inflammation, destruction joint, Chronic arthritis	Altered Intercellular Communication	Elevated levels of soluble interleukin-1 receptor type II and interleukin-1 receptor antagonist in patients with chronic arthritis: correlations with markers of inflammation and joint destruction.	9627018
Inflammation, Sinusitis	Altered Intercellular Communication	Chronic sinusitis is a common disease characterized by persistent inflammation of the sinus mucosa.	9627241
Inflammation, Retinitis	Altered Intercellular Communication	Visual acuity, media inflammation and clarity, resolution of active retinitis, and appearance of recurrence were observed.	9627653
Helicobacter pylori, Ulceration, CTCAE, Gastritis	Altered Intercellular Communication	Histamine, xanthine oxidase generated oxygen-derived free radicals and Helicobacter pylori in gastroduodenal inflammation and ulceration.	9628263
Communicable Diseases, Inflammation, Reproductive tract infection	Altered Intercellular Communication	Though detailed cytological and microbiological diagnostic procedures are routinely carried out in male genital tract infection, the correct diagnosis and localization of inflammation or infection is often difficult.	9629442
Inflammation, neutrophil	Altered Intercellular Communication	To delimit genital tract inflammation from non-inflammatory patients, cutpoint levels for PMN elastase of 230 ng ml-1 and for C3c of 0.01 g l-1 were suggested.	9629442
Hypophysitis, CTCAE, Granulomatous inflammation, Sarcoidosis, Pituitary Gland, Abscess of pituitary	Altered Intercellular Communication	Inflammatory lesions of the hypophysis include lymphocytic hypophysitis, pituitary abscess, and granulomatous inflammation, with or without specific infections (i.e., sarcoidosis, mycobacteria).	9630181
Epilepsy, Temporal Lobe, Seizures	Altered Intercellular Communication	In humans, these findings support the hypothesis that glutamate receptor subunits are increased in association with chronic temporal lobe seizures, which may enhance excitatory neurotransmission and seizure susceptibility.	9630240
Acute inflammation, Endophthalmitis	Altered Intercellular Communication	There was no significant postoperative inflammation, one case of hypotony and no suggestion to date of sympathetic ophthalmia.	9630294
Inflammation, Chorioamnionitis	Altered Intercellular Communication	The presence of chorioamnionitis, local inflammation of the fetal membranes, was found by pathological examination after the delivery.	9631597
Inflammation, Dental caries, Xerostomia, Keratoconjunctivitis Sicca, GYPB gene, "Sjogrens Syndrome", Arthritis, Respiratory Tract Infections	Altered Intercellular Communication	We describe a 49-year-old patient with lip biopsy proven Sjogren's syndrome (SS) and keratoconjunctivitis sicca, who had dental caries, xerostomia, recurrent upper respiratory tract infections, arthritis in her hands, elbows and knees, and recurrent parotid inflammation.	9632092
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	There were no cases of missed appendicitis in this trial, and all removed appendices showed signs of inflammation at histology.	9632860
Inflammation, Squamous metaplasia, Hyperplasia, Granuloma, Foreign-Body	Altered Intercellular Communication	The changes observed included polypoid hyperplasia (11 of 18 patients) between and around the stent mesh wires, nonkeratinizing squamous metaplasia (two) or hyperkeratotic squamous metaplasia (seven), chronic inflammation (15) with prominent plasma cell infiltrates (11), variable foreign-body granuloma (two) and microabscess formation (five), usually associated with clefts formed around the stent wires (three of five).	9634054
Inflammatory abnormality of the eye	Altered Intercellular Communication	Much of this elevation appears to be the result of reduced tear turnover, which may form an important positive feedback mechanism encouraging tear stagnation and the perpetuation of ocular surface inflammation.	9634922
Gingivitis	Altered Intercellular Communication	Children with a CD4:CD8 < 0.5 who showed a greater DMFT/dmf index also showed greater gingival inflammation.	9635311
Gingivitis, Dental caries	Altered Intercellular Communication	In this study, children with greater caries experience showed more gingival inflammation.	9635311
Inflammation, Destruction (action)	Altered Intercellular Communication	In fact, we have observed decreases of IL-1 and TNF-alpha, involved in cartilage inflammation and destruction, and increases of IGF-1 that have a protective influence on the cartilage.	9635373
Inflammation, Scleritis	Altered Intercellular Communication	Scleritis is a chronic inflammation of the scleral coat of the eye.	9635385
Inflammation, Traumatic injury	Altered Intercellular Communication	Varices are most commonly seen in female professional vocalists and may be secondary to repetitive trauma, hormonal variations, or repeated inflammation.	9635456
Inflammation, Traumatic injury	Altered Intercellular Communication	Varices are most commonly seen in female professional vocalists and may be secondary to repetitive trauma, hormonal variations, or repeated inflammation.	9635456
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Analysis of the UC group showed that the degree of inflammation affected the linear density of substance fibers, with "moderate" cases presenting the highest linear density and "severe" cases the lowest.	9638489
Iris bleeding, Acute inflammation, Decreased translucency, Corneal burn	Altered Intercellular Communication	Complications appeared to be less common in our patients: iris bleeding was only seen in 5.0% cases; the postoperative inflammation was mild; corneal burns, localized lenticular opacities and closure of iridectomies were less frequent.	9639843
Intraocular inflammation	Altered Intercellular Communication	Within the limits of this retrospective study and taking into account that fibrin may resolve spontaneously, it appears that topical tPA drops are not effective for the liquefaction of intraocular fibrin after surgery or in association with intraocular inflammation.	9640569
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Our results suggested that mucosal NO could be a marker for the extent of inflammation and its various actions correlated with the pathogenesis, natural history and prognosis of UC.	9641303
Inflammatory disease of mucous membrane	Altered Intercellular Communication	This novel NO electrode may contribute to understanding the role of NO in colonic mucosal inflammation.	9641303
Inflammation, Thyroid dysfunction	Altered Intercellular Communication	There were never any systemic signs of inflammation or thyroid dysfunction.	9641397
Angioedema, Inflammation, Fever, CTCAE, Urticaria, Weight Gain, Hypereosinophilia	Altered Intercellular Communication	The Gleich syndrome is rare and associates recurrent angioedema, urticaria, fever, weight gain and blood hypereosinophilia, underlying systemic and local inflammation.	9641577
Simple Pulmonary Eosinophilia, Eosinophilic inflammation	Altered Intercellular Communication	Mechanisms of acute eosinophilic inflammation in a case of acute eosinophilic pneumonia in a 14-year-old girl.	9641579
Fibrosis Assessment, Intrahepatic Route of Drug Administration	Altered Intercellular Communication	Furthermore, hepatic histopathological changes of four patients were assessed after 1 year of treatment, and an improvement of intrahepatic inflammation, but not fibrosis, was observed.	9641646
Parkinson Disease, palladium	Altered Intercellular Communication	Monoamine oxidase (MAO), which exists in two forms (MAOA and MAOB), plays an important role in the oxidative metabolism of neurotransmitters such as dopamine, and has been implicated in the etiology of Parkinson's disease (PD).	9642149
Lichen - organism, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Also, treatment of lichen planopilaris forms in which fibrosis predominates over inflammation is similarly problematic, but the natural course of these diseases seems to be self-limited.	9642560
Inflammation, Pseudoexfoliation	Altered Intercellular Communication	The low frequency of an inflammatory response indicates that the presence of pseudoexfoliation does not significantly increase the risk of inflammation.	9642589
Refractory anemias, Inflammation	Altered Intercellular Communication	Immune inflammation in RA develops with growing neopterin concentration in the serum.	9644738
Inflammation	Altered Intercellular Communication	This concentration well correlates with inflammation activity and intensification of systemic symptoms.	9644738
Refractory anemias, Inflammation	Altered Intercellular Communication	Neopterin measurements may be important for determination of inflammation activity in RA.	9644738
bone destruction	Altered Intercellular Communication	We propose that antigen-recognition events are critically involved in the development of periprosthetic inflammation and that the functional commitment of T cells recruited to the periprosthetic region influences whether periprosthetic inflammation is complicated by bone destruction.	9645758
Chorioretinitis, Inflammation, Vitritis	Altered Intercellular Communication	Characteristic signs of MCP are punched-out, white chorioretinal lesions of the lower fundus periphery, chronic smoldering chorioretinal inflammation, vitritis, and mild inflammation of the anterior chamber.	9646091
Hepatitis	Altered Intercellular Communication	The increase of C3 concentration in PBC does not reflect liver inflammation, since serum levels of C-reactive protein are normal.	9646840
Inflammation, Hypersensitivity	Altered Intercellular Communication	Increases in nasal DGMC and goblet cells differentially relate to specific clinical patterns of nasal cellular inflammation and aeroallergen hypersensitivity.	9647270
Cough variant asthma, Inflammation, Asthma	Altered Intercellular Communication	In conclusion, eosinophilic inflammation is involved in cough variant asthma as well as in classic asthma.	9648956
Cholecystitis	Altered Intercellular Communication	Laparoscopic cholecystectomy for the various types of gallbladder inflammation: a prospective trial.	9649044
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Colonic epithelial cells of patients with UC express DAF in relation to the severity of mucosal inflammation.	9649185
Crohn Disease, Inflammation	Altered Intercellular Communication	Although intraoral involvement in Crohn's disease (CD) is observed in only approximately 9% of cases, oral inflammation precedes intestinal symptoms of CD in about 60% of these patients.	9649656
Bronchitis, Chronic, Inflammation	Altered Intercellular Communication	Cellular and molecular characteristics of inflammation in chronic bronchitis.	9650009
inflammatory joint disease	Altered Intercellular Communication	Thirty per cent of patients with inflammatory joint disease reported improvement compared with 17% of those with non-inflammatory conditions (Mann-Whitney U, P = 0.019).	9651077
Inflammation, "Alzheimers Disease", Neurotoxicity Syndromes, Data types - Address	Altered Intercellular Communication	Several converging lines of evidence suggest that beta-amyloid and inflammation may be linked in the pathogenesis of Alzheimer disease (AD), but the mechanism of beta-amyloid neurotoxicity is unclear.	9651139
Inflammatory abnormality of the eye, Thrombophlebitis	Altered Intercellular Communication	Change of area or number of mucocutaneous lesions, grading score for thrombophlebitis and ocular inflammation, haematological and biochemical parameters and number of episodes during the pretreatment period and the follow-up.	9651559
Inflammation	Altered Intercellular Communication	Three workers had at biopsy diffuse interstitial inflammatory changes: two of them were asymptomatic with normal chest X-ray films, and one had clinically evident disease with severe giant cell inflammation.	9651628
Inflammation, Tracheal Stenosis, Stenosis of bronchus	Altered Intercellular Communication	Endoscopic examination showed moderate to severe inflammation in 8/9 patients; tracheal stenosis was present in 6/9 patients, bronchial stenosis in 4/9 patients, and tracheal collapse in 7 cases.	9653428
Injury of cornea, Inflammatory abnormality of the eye	Altered Intercellular Communication	Based on our experience, residual perfluorocarbon liquid droplets in the anterior chamber are well tolerated and do not induce corneal damage or ocular inflammation.	9654414
Rupture, Inflammation, External injury	Altered Intercellular Communication	We considered that the rupture was caused not by external injury but by inflammation after plication for diaphragm eventration three years and ten months before.	9654933
Airway structure, Symptoms, Respiratory Hypersensitivity	Altered Intercellular Communication	Epidemiological association of airway inflammation with asthma symptoms and airway hyperresponsiveness in childhood.	9655704
Airway structure, Asthma	Altered Intercellular Communication	The role of airway inflammation in childhood asthma is not well defined, despite modern treatment approaches recommending potent anti-inflammatory therapy for an increasing number of children.	9655704
Airway structure	Altered Intercellular Communication	Interestingly, boys were more likely than girls to have features of airway inflammation (sputum mast cells, OR 3.33, 1.15-9.65; nasal eosinophils, OR 3.25, 1.72-5.	9655704
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation with eosinophils and mast cells is likely to be important in the pathogenesis of asthma in childhood.	9655704
Inflammation	Altered Intercellular Communication	These findings suggest that frosted branch angitis is a manifestation of inflammation in the retina and the choroid.	9656692
Aneuploidy, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	These observations suggest that telomere shortening in the colonic mucosa of individuals with UC may represent the history of mucosal inflammation during disease of long duration, and that it may contribute to aneuploidy in UC.	9658312
Inflammation, Melena	Altered Intercellular Communication	The melena was ameliorated, but inflammation of the small intestine persisted.	9658323
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Stool levels of myeloperoxidase in active inflammatory bowel disease patients increased significantly, and correlated with laboratory parameters and endoscopic grade of inflammation.	9658754
Mutation, Inflammation	Altered Intercellular Communication	Pathogenetic alterations were determined by immunohistochemical staining of various cell surface molecules known to be involved in the pathogenesis of inflammation.	9658802
Inflammation, Postoperative Period, intracranial lesion	Altered Intercellular Communication	To avoid inflammation, the immediate removal of the foreign material is recommended in cases with considerable intracranial lesions: post-operative neurologic and intensive care monitoring should be provided.	9658835
Wheezing, Eosinophilic inflammation	Altered Intercellular Communication	Eosinophil inflammation is present from the beginning of the disease in the children who are going to continue with wheezing at age 5 years.	9659092
Inflammation	Altered Intercellular Communication	No differences were found for age, sex, gastric corpus or antrum, or degree of inflammation in the gastric lamina propria.	9659261
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	VDCs were detected also in the media beneath atherosclerotic lesions and in the adventitia, where they were mostly around vasa vasorum, especially in areas exhibiting signs of acute inflammation.	9659465
Inflammation, Necrosis	Altered Intercellular Communication	Colonoscopy confirmed ulcerations in the terminal ileum and cecum, with biopsies showing necrosis and inflammation.	9659565
Data types - Address	Altered Intercellular Communication	Our results might suggest a possible pathogenetic role of neurotransmitter amino acids in AD.	9660105
Inflammation, Endothelium, Thrombosis, Dental Plaque	Altered Intercellular Communication	Evidence suggests that mediators of inflammation are not only instrumental in the formation of plaque but may also be involved in the rapid progression of atheromatous lesions leading to plaque fissuring, endothelial injury, and intraluminal thrombosis.	9660396
Inflammation, Dental Plaque	Altered Intercellular Communication	An elevation in ICAM-1 expression in symptomatic versus asymptomatic plaque suggests that mediators of inflammation are involved in the conversion of carotid plaque to a symptomatic state.	9660396
Necrosis	Altered Intercellular Communication	The majority of the smears were characterized by a bloody background with necrotic debris and extensive acute inflammation.	9661917
Inflammation, Pancreatitis Necrotizing	Altered Intercellular Communication	EUS detected pancreatic necrosis (100%), as well as inflammation in the lesser sac (100%) and retroperitoneum (81%), which CT confirmed.	9663246
Inflammation, Degenerative disorder, Adiposis Dolorosa	Altered Intercellular Communication	These patients had mild inflammation, soft tissue rheumatism, injury or degenerative disease.	9663314
Inflammation	Altered Intercellular Communication	In 54 (18.0%) of the injected joints, the inflammation recurred within 6 months of injection.	9663477
Inflammation	Altered Intercellular Communication	These alterations may include inflammation and epithelial proliferation, but as a rule, the changes are reversible and promptly resolve when gum-chewing activity is discontinued.	9663672
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	TNFalpha antibodies have been shown to be beneficial in animal models of bowel inflammation and in Crohn's disease but have not previously been studied in ulcerative colitis.	9663825
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The presence of activated T cells and TH1 cytokine transcripts in chronic joint lesions of patients with OA suggests that T cells contribute to chronic inflammation in a large proportion of these patients.	9665944
COLLAGENOSIS, FAMILIAL REACTIVE PERFORATING, Vestibular dysfunction, Inflammatory abnormality of the eye, Inflammatory disorder of cartilage, Polyarthritis	Altered Intercellular Communication	A 15-year-old girl having chondritis of bilateral auricles, nose and respiratory tract, ocular inflammation, cochlear and vestibular dysfunction and seronegative polyarthritis was diagnosed as RPC, and oral corticosteroid was initially effective.	9666681
Inflammation, Data types - Address	Altered Intercellular Communication	These results suggest that an elevation of cAMP-PDE activity is closely related to a predisposition to respiratory atopy, and does not follow inflammation in AD patients.	9666832
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	Hypoalbuminemia is often interpreted as a marker of poor nutrition, but serum albumin and cholesterol levels can also be low as part of a cytokine-mediated acute-phase reaction to acute or chronic inflammation.	9669431
Inflammation, Carcinoma of lung, Hilar lymph node	Altered Intercellular Communication	These results do not support the possibility that FN levels in BALF were a general marker of lung cancer, and suggest that FN may mark the existence of pathologic lung processes associated with inflammation and, perhaps tissue repair after bronchopulmonary injury.	9670297
Inflammation, Retinitis Pigmentosa	Altered Intercellular Communication	RP is an unusual systemic disorder characterized by widespread inflammation and destruction of cartilage tissues.	9670304
Degenerative disorder	Altered Intercellular Communication	Genetic factors, viral or autoimmune inflammation or both, and apoptosis are also involved in the degenerative disorder.	9670499
Peeling of skin, Postobstructive pneumonia	Altered Intercellular Communication	Each open lung biopsy specimen was scored semiquantitatively for alveolar desquamation, alveolar septal inflammation, inflammatory airway narrowing, obstructive pneumonitis, and lymphoid nodules.	9671423
Inflammation, Honeycomb appearance	Altered Intercellular Communication	In patients with UIP, more active inflammation of the pulmonary interstitium results in faster progression of honeycombing in long-term follow-up.	9671423
Inflammation	Altered Intercellular Communication	To assess the correlation between laser flare measurements and anterior chamber IgG/albumin concentrations in eyes with mild to severe inflammation.	9672218
Inflammation	Altered Intercellular Communication	Antineutrophil cytoplasmic antibody was positive in a perinuclear pattern (pANCA) and the increased dose of prednisolone to 40 mg/day resulted in subsidence of the subretinal inflammation.	9672222
Stomatitis, Pancreatitis, Chronic	Altered Intercellular Communication	This chronic inflammation of the gastric mucosa could contribute to determining the changes in gastric physiology described in patients with chronic pancreatitis.	9672337
Inflammation, immunoglobulin A, Gliadin, Celiac Disease, Exocrine pancreatic insufficiency	Altered Intercellular Communication	Initially, latent celiac disease was suggested because of normal endoscopic findings, the finding of non-specific inflammation on histological evaluation of duodenal biopsies, positive IgA and IgG gliadin, as well as endomysium antibodies and exocrine pancreatic insufficiency.	9672361
physiopathological	Altered Intercellular Communication	Couples with either one-sided tubapathology, hormonal dysfunction, idiopathic infertility, or andrological indication were selected.	9673879
Cataract, Inflammation	Altered Intercellular Communication	Ketorolac tromethamine 0.5% and diclofenac sodium 0.1% may be as effective and as safe as prednisolone acetate 1% in controlling inflammation following cataract extraction.	9674003
Inflammation, Chronic infectious disease, Fibrosis Assessment, Bodily secretions, Destruction (action)	Altered Intercellular Communication	Stasis of viscid secretions in cystic fibrosis (CF) leads to chronic infection, inflammation, and lung destruction.	9675436
Infection caused by Helicobacter pylori	Altered Intercellular Communication	We attempted to identify the effect of Helicobacter pylori infection on apoptosis in the gastric epithelium and its possible relation to epithelial-cell proliferation and mucosal inflammation.	9675649
Refractory anemias, Inflammation	Altered Intercellular Communication	Four lesions were percutaneously biopsied and showed chronic inflammation consistent with RA.	9676452
Inflammation, Muscle fiber atrophy	Altered Intercellular Communication	Whether this is directly associated with the systemic inflammation and the musculoskeletal symptoms or is mainly due to muscle fiber atrophy could not be determined.	9676767
Inflammation	Altered Intercellular Communication	Conversely, on the basis of semiquantitative analysis of the images, leukocyte scintigraphy seemed to characterize the grade of inflammation better than did nanocolloid scintigraphy.	9676945
Ischemia, Inflammation	Altered Intercellular Communication	The signs and symptoms relate either to ischemia or inflammation of the involved vessels, or to both.	9677733
Inflammation, Edema	Altered Intercellular Communication	In T2-weighted MRI images, increased signal intensity changes reflecting intramuscular edema and inflammation were seen in all patients in at least 1 muscle group in the thighs or calves.	9678317
Neoplasms, Reticuloendothelial System	Altered Intercellular Communication	FNA plays an important role in the preoperative and postoperative assessment of parotid masses by aiding in the evaluation of tumors in poor surgical candidates and unresectable tumors, and by identifying metastases from other sites, reticuloendothelial tumors, and nonneoplastic inflammatory conditions.	9678729
allergic inflammation, Atopic keratoconjunctivitis, Allergic Conjunctivitis	Altered Intercellular Communication	Infiltration with mast cells and eosinophils is characteristic of the chronic forms of allergic conjunctivitis such as vernal and atopic keratoconjunctivitis, and these cell types also contribute significantly to allergic inflammation in the skin.	9678838
Inflammation	Altered Intercellular Communication	Transcription factors of the nuclear factor kappaB (NF-kappaB) family play an important role in the regulation of genes involved in inflammation.	9679041
Inflammation, Ulcerative Colitis, Colitis, Diverticulitis, Crohn Disease	Altered Intercellular Communication	The number of cells showing NF-kappaB activation correlated with the degree of mucosal inflammation but was not significantly different between inflamed mucosa from patients with Crohn's disease, ulcerative colitis, and nonspecific colitis or diverticulitis.	9679041
Inflammatory disease of mucous membrane	Altered Intercellular Communication	This study shows for the first time the activation of NF-kappaB during human mucosal inflammation in situ.	9679041
Inflammation, Cluster Headache, Migraine Disorders, Pain Distress Question	Altered Intercellular Communication	This neurogenic inflammation within the meninges has been suggested as a model to explain the pain in migraine and cluster headache, and has been used to characterize the pharmacology of anti-migraine compounds.	9679775
Migraine Disorders, Neurogenic Inflammation, Cluster Headache, Headache	Altered Intercellular Communication	These data raise the possibility that neurogenic inflammation is not a major factor in headache attacks in migraine or cluster headache.	9679775
Extrapyramidal sign, Data types - Address	Altered Intercellular Communication	We suggest that this increased GABAergic neurotransmission may explain extrapyramidal signs often observed in AD.	9681468
Inflammation	Altered Intercellular Communication	Recent studies have suggested that cell adhesion plays an important role in the development and regulation of inflammation.	9681675
Inflammation, IGA Glomerulonephritis	Altered Intercellular Communication	Among our cases of IgA glomerulonephritis (IgAGN), 10% show necrotizing/extracapillary lesions involving a small percentage of glomeruli and associated with a certain degree of inflammation in absence of glomerular and interstitial scarring.	9681709
Inflammation, Airway Obstruction, Osage language	Altered Intercellular Communication	We hypothesise that patients with OSA have increased upper airway reactivity, secondary to inflammation of the epithelial lining of the upper airway following the repeated injury of nocturnal airway obstruction, allowing the facilitated passage of inhaled irritants to the subepithelial receptors.	9682183
Inflammation, Optic Atrophy, Hereditary, Leber	Altered Intercellular Communication	The LHON revealed general axonal depletion centrally, fibrocytic scarring, scattered "degeneration dust," and evidence of minimal inflammation, with residual axons limited to superior and temporal peripheral clusters.	9682705
Inflammation, Optic Atrophy, Hereditary, Leber	Altered Intercellular Communication	In LHON, degenerated axons and minimal grade of inflammation were obvious, implicating a more "active" pathologic process.	9682705
Inflammation	Altered Intercellular Communication	The data indicate that at present no arguments exist that the effect of T-cell-directed interventions on synovial inflammation might vary in different stages of the disease.	9683554
Thyroiditis	Altered Intercellular Communication	The differences between these forms provide diagnostic criteria that could be useful for the preoperative management of patients affected by suspicious, inflammation like thyroid lesions.	9684593
Inflammation, Liver diseases	Altered Intercellular Communication	Inflammation can cause an elevation of serum sVAP-1 levels, because sVAP-1 concentrations in patients with certain liver diseases were two- to fourfold higher than those in normal individuals.	9686623
Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	This is higher than the ferritin level of < or =50 microg/L cited in standard textbooks as evidence of iron deficiency in patients with inflammation, infection, or malignancy.	9686711
Cataract, Inflammation	Altered Intercellular Communication	The parameters compared were pachymetry of the cornea, corneal surface changes, intraocular pressure (IOP) and the degree of inflammation of the anterior chamber at one, three and six weeks after cataract surgery.	9686850
Cataract, Inflammation	Altered Intercellular Communication	Both drugs were well tolerated and may be safely used to reduce inflammation for cataract surgery.	9686850
Inflammation, Communicable Diseases, Infection, Tissue injury, Cessation of life	Altered Intercellular Communication	These findings are consistent with the supposition that uncontrolled systemic inflammation, initially triggered by tissue injury and isolated infection, persists despite control of these infections and leads to multiple organ failure and death.	9688194
Inflammation, Demyelination, MS gene, Optic Neuritis	Altered Intercellular Communication	Soluble ICAM-1, demyelination, and inflammation in multiple sclerosis and acute optic neuritis.	9688333
Ischemia, cell injury	Altered Intercellular Communication	The excitatory neurotransmitter glutamate is not only a metabolic product, but is also thought to promote ischaemia induced cell injury if released into the extracellular space.	9689326
Inflammation, Bronchiectasis	Altered Intercellular Communication	The presence of fungi in the mucous plugs may have caused marked inflammation in the wall around the BMP, which may have made the walls fragile and caused central bronchiectasis.	9691645
Unknown (origin) (qualifier value), Inflammation, Aneurysm	Altered Intercellular Communication	The aneurysms in these two cases were idiopathic: (1) there were no histologic findings that would implicate specific chronic inflammation.	9691655
Inflammation, Tuberculosis	Altered Intercellular Communication	This may suggest that the lymphocytic reaction in the pulmonary tissue is major in tuberculosis (as in other pulmonary granulomatoses) and different factors among which there are most important ones, including lung tissue decay, bacterial abundance, concurrence of nonspecific inflammation, appear as higher rates and magnitude of neutrophilic reactions.	9691686
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Many kinds of oxidative stress are known to attack the immune systems and to bring out inflammation and autoimmunity.	9691766
Abnormal renal function, Inflammation, Asthma, Asthma, Occupational	Altered Intercellular Communication	Despite a similar degree of functional abnormalities, subjects with asthma due to LMWCs and still exposed to the occupational sensitizer showed a lower degree of eosinophilic inflammation and a higher degree of neutrophilic inflammation in the airways than subjects with occupational asthma due to HMWCs or non-occupational asthmatics.	9692121
Airway structure, Asthma, Occupational	Altered Intercellular Communication	Furthermore, sputum eosinophil counts detect, better than blood indices, the degree of airway inflammation in both occupational and non-occupational asthma.	9692121
Airway structure	Altered Intercellular Communication	It has been hypothesized that concentrations of exhaled nitric oxide (NO) may be related to the extent of cytokine-mediated airway inflammation.	9692122
Inflammatory, Nasal inflammation	Altered Intercellular Communication	We speculate that the allergic inflammatory response may influence the nasal NO levels and that NO measurements may be a useful marker of nasal inflammation.	9692122
Inflammation, Fibrosis Assessment, Cholelithiasis	Altered Intercellular Communication	LSC was performed in 29 patients with severe inflammation or fibrosis of the gallbladder associated with gallstone disease over a 23-month period.	9692560
Orbital Pseudotumor	Altered Intercellular Communication	Idiopathic sclerosing inflammation has commonly been found in the diffuse orbital tissues.	9693294
Inflammation	Altered Intercellular Communication	We report the inflammation of the right upper eyelid in a 65-year-old man.	9693294
Orbital Pseudotumor	Altered Intercellular Communication	We believe that idiopathic sclerosing inflammation of the upper eyelid, as demonstrated in our patient, may be rare.	9693294
Communicable Diseases, Inflammation	Altered Intercellular Communication	No ascending infection occurred, even when the abdominal tip of the shunt came in close contact with the focus of inflammation.	9693325
Inflammation	Altered Intercellular Communication	In conclusion, these results suggest that sICAM-1 levels in SpA may reflect the acute phase of inflammation.	9694052
Portal inflammation	Altered Intercellular Communication	A pronounced undulation in the portal vein was associated with portal inflammation but not with other parameters of the histologic activity index or the intrahepatic fat deposition.	9694471
Inflammation, Anemia	Altered Intercellular Communication	[Detection and treatment of iron deficiency anaemia coexisting with inflammation prevalent in aged individuals].	9695670
Inflammation, Anemia, idarubicin	Altered Intercellular Communication	When surveyed in a general hospital admitting 222 patients, anaemias were detected in 95 out of 190 patients aged above 60:82 inflammation anaemia, 9 IDA including 6 cases with inflammation and 4 other anaemias.	9695670
Inflammation, idarubicin	Altered Intercellular Communication	Thus, the treatment of aged patients with IDA coexisting with inflammation seems to be comparably effective as for IDA only.	9695670
Inflammation, Lymphohistiocytosis, Hemophagocytic	Altered Intercellular Communication	Lymph node biopsy revealed subacute necrotizing inflammation and there were on signs of the hemophagocytic phenomenon in bone marrow.	9695672
Pheochromocytoma, Headache	Altered Intercellular Communication	Headache is an important diagnostic element in pheochromocytoma and it may characterize a body reaction to pathological hormonal oscillations.	9698737
Pain Distress Question, Inflammation	Altered Intercellular Communication	It asked 2127 persons whether they had, in the previous 6 months, experienced any form of unduly prolonged pain (as distinct from brief intercurrent self-limiting episodes related to injury inflammation etc.)	9699096
Epithelial cyst, Inflammation, Dystrophic calcification, Rupture	Altered Intercellular Communication	Some intact epidermoid cysts were also present, suggesting that dystrophic calcification, and possibly inflammation and rupture of epidermoid cysts, may be the main pathogenetic mechanism of the disease in most reported cases.	9700381
Orbital Pseudotumor	Altered Intercellular Communication	They can reach a large size and create significant orbital inflammation.	9700739
Gastritis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Recently 16 cases of G. hominis-associated gastritis were found in 257 Thai individuals, which made it possible to study the biological characteristics of G. hominis and its relationship with gastric mucosal inflammation.	9701012
Inflammation	Altered Intercellular Communication	Mucosal inflammation was usually severe in H. pylori, but neutrophil polymorph infiltration was often mild and focal in G. hominis infection.	9701012
Inflammation	Altered Intercellular Communication	It is suggested that G. hominis may be partly responsible for the mucosal inflammation and some malignant-associated lesions.	9701012
Infection caused by Helicobacter pylori, Hypergastrinemia (finding), Inflammatory disease of mucous membrane, Gastritis, Atrophic	Altered Intercellular Communication	Severe hypergastrinaemia patients had a longer duration of treatment (80 vs. 55 months; P = 0.047) and were characterized by a higher prevalence of H. pylori infection (9/12 vs. 2/14, P = 0.004), corpus mucosal inflammation and atrophic gastritis (P < 0.04).	9701523
Inflammation, Medically Unexplained Symptoms	Altered Intercellular Communication	These syndromes can involve many somatic symptoms consistent with possible inflammation.	9701717
Inflammation	Altered Intercellular Communication	Immunological or neurogenic triggering might account for such inflammation.	9701717
Granulomatous inflammation, Vasculitis, CTCAE, Granuloma	Altered Intercellular Communication	The histopathological picture shows granulomatous inflammation with epitheloid cells, granulomas, and general vasculitis.	9701761
Iridocyclitis, Iritis, Uveitis	Altered Intercellular Communication	Uveal inflammation, present in all the patients varied from mild iritis in 4 individuals to severe iridocyclitis in the remaining 4.	9702597
Inflammation, Peripheral Neuropathy	Altered Intercellular Communication	We conclude that CD1 molecule expression is upregulated in peripheral neuropathy, especially in association with inflammation.	9702686
Refractory anemias, Inflammation	Altered Intercellular Communication	Signs of inflammation were also demonstrated in ST from clinically uninvolved knee joints of all RA patients evaluated.	9704648
vascular inflammations, Electrocardiogram: myocardial infarction (finding), Restenosis	Altered Intercellular Communication	Acute myocardial infarction and increased soluble intercellular adhesion molecule-1: a marker of vascular inflammation and a risk of early restenosis?	9704683
vascular inflammations, Coronary Restenosis	Altered Intercellular Communication	A persistent increase in plasma sICAM-1 levels may indirectly implicate vascular inflammation, which could predict the risk of early coronary restenosis after emergency angioplasty in patients with AMI.	9704683
Inflammation, Varicose Ulcer, Lipodermatosclerosis, Connective Tissue, Stasis dermatitis	Altered Intercellular Communication	We conclude that PDGFR-alpha, PDGFR-beta and VEGF play an important role in mediating inflammation and epithelial hyperproliferation in venous eczema, inducing connective tissue sclerosis in lipodermatosclerosis, and causing the reduced reepithelialization tendency in venous ulcers.	9705159
Sarcoma, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	The prominent inflammation and fibrosis seen histologically in acral myxoinflammatory fibroblastic sarcoma simulate a reactive process.	9706971
Sarcoma, Inflammation, Tenosynovitis	Altered Intercellular Communication	The intimate relationship with the synovium, the frequent association with tenosynovitis, and the prominent inflammatory infiltrate suggest that inflammation may play a role in the pathogenesis of acral myxoinflammatory fibroblastic sarcoma.	9706971
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	Chronic inflammation, both endoscopic and histologic, in a contiguous and symmetric distribution is said to be important in distinguishing ulcerative colitis (UC) from Crohn's disease.	9706978
Inflammation, Proctosigmoiditis	Altered Intercellular Communication	Of the three patients in whom the maximal extent was proctosigmoiditis, in one the inflammation disappeared.	9706978
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	Our results indicate that in long-standing UC (1) histologic disease may revert to normal mucosa, (2) because endoscopy alone may be insufficient to identify the mucosa as normal, biopsies should also be performed on the endoscopically normal mucosa, (3) the full extent of UC often is not established by a single set of biopsies, and (4) nondiffuse chronic inflammation and rectal sparing occurs in UC and are not necessarily markers of Crohn's disease.	9706978
Inflammation, Atrophic	Altered Intercellular Communication	Mucosal inflammation, atrophy, and IM were evaluated in biopsy specimens from antrum and corpus.	9707050
Hepatic inflammation	Altered Intercellular Communication	Circulating lactoferrin is cleared in the liver, but little is known about the implication of lactoferrin in hepatic inflammation.	9707061
Inflammation, Carotid Stenosis, Dental Plaque	Altered Intercellular Communication	Inflammation in high-grade carotid stenosis: a possible role for macrophages and T cells in plaque destabilization.	9707204
Inflammation	Altered Intercellular Communication	Blocking the CXC chemokine activity associated with brain inflammation inhibits neutrophil-mediated blood-brain barrier damage and represents a significant therapeutic possibility.	9707404
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	For all biopsies (with or without active inflammation) reports highly suggestive or suggestive of Crohn's disease had a sensitivity of 50%; for ulcerative colitis the comparable figure was 62%.	9708205
Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Of 655 FNAs, reactive or benign changes were present in 37% confirmed or suspected malignancy in 13%, specific infection with stainable organisms in 14%, and inflammation in 16%.	9710692
Inflammation	Altered Intercellular Communication	The increased colonic permeability may be explained by inflammation and the resultant loss of mucosal integrity.	9712240
Inflammation, Purulence	Altered Intercellular Communication	The concentrations of IgG subclasses in sputum were partly dependent upon the degree of inflammation as assessed by the macroscopic appearance of purulence.	9713445
Inflammation, Intestinal Obstruction, Acute appendicitis NOS (disorder)	Altered Intercellular Communication	Intestinal obstruction is the most common complication in the adult, and inflammation mimicking acute appendicitis may also occur.	9715222
Macular Edema, Cystoid, Periphlebitis, Vitreous inflammatory cells	Altered Intercellular Communication	Phakic patients with cystoid macular edema, retinal periphlebitis, and vitreous inflammation.	9715682
Vitreous inflammatory cells, Macular Edema, Cystoid, Periphlebitis	Altered Intercellular Communication	Nineteen phakic patients (35 eyes) with vitreous inflammation, cystoid macular edema, and/or retinal periphlebitis of unknown cause.	9715682
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Participation of peripheral polymorphonuclear leukocytes in the oxidative stress and inflammation in patients with essential hypertension.	9715783
Inflammation, Hypertension, CTCAE, Corneal Endothelial Cell Loss	Altered Intercellular Communication	Oxidative stress and inflammation have recently been linked to endothelial damage in essential hypertension (EH).	9715783
Inflammation, Necrosis	Altered Intercellular Communication	PMN necrosis further exacerbates inflammation and promotes chemotaxis and PMN recruitment.	9715783
Inflammation, Corneal Endothelial Cell Loss, Atherosclerosis	Altered Intercellular Communication	Oxidative stress and inflammation will result in endothelial damage and atherosclerosis in the long run.	9715783
Inflammation, Hypoxia, Chronic heart failure	Altered Intercellular Communication	We hypothesized that chronic heart failure as a model of systemic hypoxia may result in systemic inflammation.	9717010
Inflammation, Pregnancy Complications, Infectious	Altered Intercellular Communication	The signs of systemic inflammation disappeared following successful mechanical circulatory support, but persisted in patients who developed infectious complications.	9717010
Inflammation	Altered Intercellular Communication	Post-operative inflammation following deep sclerectomy with collagen implant versus standard trabeculectomy.	9717655
Inflammation	Altered Intercellular Communication	An investigation was carried out to compare post-operative inflammation following deep sclerectomy with collagen implant (DSCI) versus standard trabeculectomy.	9717655
Inflammation, Glaucoma associated with ocular trauma, Uveitis	Altered Intercellular Communication	Eyes at increased risk of post-operative inflammation, such as those with uveitic or traumatic glaucoma, may benefit from this procedure.	9717655
Inflammation, Unspecified visual loss	Altered Intercellular Communication	The second patient consulted 8 years after a perforating injury of his right eye by a metallic foreign body because of recent visual loss and inflammation in his good left eye.	9717662
Refractory anemias, Inflammation	Altered Intercellular Communication	The presence of germinal centre-like structures and clonotypic expansion of lymphocytes in RA synovia may indicate a site-specific immune response to local antigens, rather than passively entrapped immune cells, that sustains synovial inflammation.	9717979
Hepatic inflammation, FAM126A gene	Altered Intercellular Communication	Viral replication persisted in a significant portion of HCC patients and a higher prevalence of hepatic inflammation was noted in patients with HCV- and, possibly, HDV-related HCC.	9719234
Inflammation, pancreatic juice, Gallbladder Carcinoma	Altered Intercellular Communication	These findings suggest that pre-existing inconspicuous inflammation of the biliary tract due to reflux of pancreatic juice is involved in elevation of serum and bile cytokines, and that cytokines may participate in gallbladder carcinogenesis associated with AJPBD.	9719251
Blood Clot, Vascular Invasion Assessment	Altered Intercellular Communication	Hormonal factors may have a permissive role in thrombus formation or neoplastic vascular invasion.	9719503
Infarction, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	We assess the role of acute prostatic infarction and prostatic inflammation in causing acute urinary retention in patients with benign prostatic hyperplasia (BPH).	9720549
Infarction, Inflammation	Altered Intercellular Communication	The prostatic chips in each group were examined by 1 histopathologist, who was unaware of the clinical presentation of the patient, for changes of infarction, acute and chronic inflammation, and predominant histological pattern.	9720549
Infarction, Inflammation	Altered Intercellular Communication	Prostatic infarction and inflammation had no role in the etiology of acute urinary retention due to BPH.	9720549
Inflammation	Altered Intercellular Communication	IL-1alpha has been reported to play an important role in inducing the expression of cytokines IL-6, IL-8, and GM-CSF during inflammation.	9721877
Diabetes Mellitus, Insulin-Dependent, Inflammation, Periodontal Diseases, diabetic	Altered Intercellular Communication	Thus, we suggest that insulin-dependent diabetes mellitus is a significant risk factor for more severe periodontal disease because, as compared to non-diabetics, diabetic subjects react with an abnormally high degree of inflammation to an equivalent bacterial burden.	9722689
Inflammation, Endocarditis	Altered Intercellular Communication	Pouch hematoma or inflammation was common (58%), but other predisposing factors for endocarditis were rare.	9723637
Inflammation	Altered Intercellular Communication	The matrix metalloproteinases (MMPs) MMP2 and MMP9 play a significant role in epidermal detachment, inflammation and re-epithelialization.	9726031
Inflammation, Gastritis	Altered Intercellular Communication	However, while there was no change in gastritis in the antrum with ranitidine, treatment with lansoprazole led to partial elimination of H. pylori with improvement of the inflammation in this part of the stomach.	9726386
Inflammation	Altered Intercellular Communication	However, only lansoprazole leads to a partial elimination of H. pylori with improvement of the inflammation in the antrum.	9726386
Neurodegenerative Disorders, Data types - Address	Altered Intercellular Communication	These data suggest that basic gene induction mechanisms, which have been conserved over long periods of evolution, that increase NF-kappaB-DNA binds ing may be fundamental in driving transcription from inflammation-related genes, such as COX-2, that operate in stressed tissues, in normally aging cell lines, and in neurodegenerative disorders that include AD brain.	9726429
Inflammation, Neoplasms	Altered Intercellular Communication	The lower figures obtained for specificity and positive predictive value reflect the fact that increased FDG uptake may be due to either tumor or inflammation.	9726451
Inflammation, Bacteriuria, Pyuria, Common Compensatory Fascial Pattern	Altered Intercellular Communication	Active inflammation with marked pyuria, bacteriuria and even moderate upper urinary tract dilation were indications for the upper urinary tract drainage with catheter-stent before and during ESWL in CCP patients.	9727311
Intraocular inflammation	Altered Intercellular Communication	No cause of neovascularization other than intraocular inflammation was detected.	9727534
Inflammation, Diffuse panbronchiolitis, Bronchiolitis	Altered Intercellular Communication	Diffuse panbronchiolitis (DPB) is a unique inflammation principally affecting the respiratory bronchioli and has been reported mainly in Japanese adults.	9727799
Inflammation, Cervical Disc Degenerative Disorder, Neoplasms, Traumatic injury, Bone structure of spine	Altered Intercellular Communication	All underwent anterior cervical plate fusion as a component of the surgical treatment for symptomatic degenerative cervical spinal disease or for vertebral destruction caused by trauma, tumor, or inflammation.	9728381
Inflammation	Altered Intercellular Communication	In specific cases, stent implantation also induces inflammation around the stent struts.	9728614
Ischemia	Altered Intercellular Communication	Compared with the median nerve, the change in ulnar nerve signal amplitude during ischemia was significantly greater after 4 min (P = 0.002).	9728852
Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Analysis of immunoglobulin A antibodies to Helicobacter pylori in serum and gastric juice in relation to mucosal inflammation.	9729526
Inflammation, Perforation (observation)	Altered Intercellular Communication	During a complicated operation perforation of a gallbladder, severely altered by inflammation, occurred and part of the concrements escaped into the peritoneal cavity.	9729908
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Plasma and muscle amino acid levels in relation to resting energy expenditure and inflammation in stable chronic obstructive pulmonary disease.	9731007
Inflammatory	Altered Intercellular Communication	It is unknown whether this disorder represents a true inflammatory vasculitis or transient vasoconstriction related to the hormonal events of pregnancy and the postpartum period.	9731629
Granulomatous inflammation, Granulomatosis with polyangiitis, Vasculitis, CTCAE, Inflammatory disorder	Altered Intercellular Communication	Wegener's granulomatosis (WG) is an inflammatory disorder characterized by granulomatous inflammation and vasculitis, and is strongly associated with antineutrophil cytoplasmic antibodies (ANCA).	9734683
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Although all three patient groups had a similar degree of liver fibrosis, both the degree of periportal inflammation and total histological activity index were significantly lower in the HGV group than in the other two groups.	9736168
Inflammation, Periodontitis, Tooth Loss	Altered Intercellular Communication	Periodontitis is a chronic inflammation of the supporting structures of the dentition which constitutes one of the most common causes of adult tooth loss.	9736373
Inflammation	Altered Intercellular Communication	Evaluation included serial CT scans, revealing increasing persistent inflammation with development of multiple renal intraparenchymal abscesses, and arteriography, showing marked degeneration of the renal artery.	9737467
Inflammation, Crohn Disease, Inflammatory disorder, Irritable Bowel Syndrome	Altered Intercellular Communication	Irrespective of stenosis or acute inflammation, patients with Crohn's disease show a higher intraluminal pressure compared to patients with non-inflammatory disease or irritable bowel syndrome.	9738268
Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels.	9738637
Inflammation, Michigan (geographic location)	Altered Intercellular Communication	Evidence of inflammation after MI is associated with increased risk of recurrent coronary events.	9738637
Inflammation	Altered Intercellular Communication	Apoptosis of neutrophils plays a critical role in the resolution of acute inflammation.	9738665
Inflammation, Traumatic injury	Altered Intercellular Communication	[Significance of systemic inflammation in 1,278 trauma patients].	9739215
Post-Traumatic Stress Disorder, Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	Using the number of fulfilled SIRS criteria for classifying systemic inflammation, its severity may be predictive for posttraumatic complications and outcome of injured patients.	9739215
Excessive tearing, Inflammation, Edema	Altered Intercellular Communication	Inflammation in the nasal mucosa may lead to epiphora by causing edema around the orifice of the nasolacrimal duct.	9740921
Inflammation, Disease remission, Crohn Disease	Altered Intercellular Communication	The study suggests that (a) smoking protects the colon from inflammation and (b) is associated with more active disease in Crohn's disease.	9741019
Dental Plaque	Altered Intercellular Communication	Inflammation of the cap or shoulder of the plaque was observed in 33% of all cross sections.	9741507
Inflammation, Dental Plaque	Altered Intercellular Communication	In addition, inflammation of the cap and shoulder of the plaque was a common finding in the atherosclerotic femoral artery.	9741507
Inflammation, Hypoxia, Hyperplasia	Altered Intercellular Communication	Morphological diagnosis is sometimes very difficult, but recently these lesions have been regarded as hyperplastic lesions arising in pulmonary neuroendocrine cells (Kultschitzky cells) and caused by chronic pulmonary damage, such as hypoxia and inflammation.	9742865
Refractory anemias, Inflammation, Tumor necrosis	Altered Intercellular Communication	In order to determine whether certain cytokine patterns locally in the joint are specifically related to the chronic inflammation in RA, the concentrations of interleukin (IL)-1alpha, IL-1beta, IL-6, IL-10, transforming growth factor-beta (TGF-beta), tumour necrosis factor-alpha (TNF-alpha) and IgG2b-inducing factor (IgG2bIF) were measured in SF from 22 patients with RA and 22 patients with other types of arthritic lesions.	9743215
Refractory anemias, Inflammation	Altered Intercellular Communication	However, no distinct cytokine profile specific for the chronic inflammation characteristic of RA was found.	9743215
Refractory anemias, Inflammation	Altered Intercellular Communication	Hence, we conclude that several different inflammatory mediators might contribute to the chronic inflammation and autoantibody production in the joint of RA patients.	9743216
Inflammation, Lymphoepithelial Lesion	Altered Intercellular Communication	Epitheliotropism or a lymphoepithelial lesion is analyzed in relation to the inflammation, observing the tendency to be larger in K-type implants with a completely-submerged technique.	9743639
Inflammation, Edema	Altered Intercellular Communication	Compared with nonsteroidal anti-inflammatory drugs (indomethacin, ibuprofen), CS appears to be more effective on cellular events of inflammation than on edema formation.	9743814
Intraocular inflammation, Lymphocyte count increased	Altered Intercellular Communication	Intraocular inflammation and the diffuse infiltrative lymphocytosis syndrome.	9744387
Conjunctivitis, Scleritis, Marginal keratitis, Orbital Pseudotumor	Altered Intercellular Communication	The common ocular manifestations include conjunctivitis, scleritis, peripheral keratitis and orbital inflammation.	9745168
Sepsis, Inflammation	Altered Intercellular Communication	Serum calcitonin precursors in sepsis and systemic inflammation.	9745444
Sepsis, Inflammation	Altered Intercellular Communication	High serum levels of the calcitonin (CT) prohormone, procalcitonin (pro-CT), and its component peptides occur in systemic inflammation and sepsis.	9745444
Necrotizing granulomatous inflammation, Giant Cell Arteritis	Altered Intercellular Communication	Giant cell arteritis is an enigmatic disease that is characterized by chronic granulomatous inflammation of the walls of large and medium-sized arteries.	9747046
Chronic lymphocytic inflammation, Inflammation	Altered Intercellular Communication	Dutcher bodies, cytologic atypia, the density of lymphoid infiltrates, invasion of the muscularis mucosae, germinal centers, reactive epithelial atypia and acute inflammation.	9747121
Inflammation, Gastric lymphoma	Altered Intercellular Communication	The presence of germinal centers, acute inflammation and reactive epithelial atypia does not exclude a diagnosis of low-grade gastric lymphoma.	9747121
Inflammation	Altered Intercellular Communication	However, Bacteroides forsythus detected by IF showed a close association with periodontal inflammation.	9747334
Inflammation, Vitreous strands	Altered Intercellular Communication	On ophthalmic examination, we found moderate inflammation in the anterior chamber and vitreous, with granular crystalline deposits on the iris, intraocular lens, and capsular bag.	9747687
Intraocular inflammation	Altered Intercellular Communication	Treatment with trimethoprim-sulfamethoxazole, cefixime, rifampin, and doxycycline resulted in improvement of systemic symptoms, but intraocular inflammation persisted.	9747687
Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation was eventually reduced with the intravenous administration of ceftriaxone sodium.	9747687
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histopathologic evaluation of a biopsy specimen of anterior orbital fat and lacrimal gland revealed fibrosis and chronic inflammation.	9747688
Inflammation	Altered Intercellular Communication	Increased release of interleukin-12p40 in MS: association with intracerebral inflammation.	9748022
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	In addition, 9 patients had pre- and post-cardiopulmonary bypass measurements of markers of myocardial ischaemia (troponine Ic) and systemic inflammation (interleukines 6 and 10, elastase).	9749176
Amenorrhea, Ovarian failure	Altered Intercellular Communication	After WBI, the patient developed ovarian failure and amenorrhea, which was confirmed by hormonal evaluation.	9749425
Dermatitis, Atopic, Psoriasis, Data types - Address, Dermatitis	Altered Intercellular Communication	Increased expression of ICAM-1 occurs in keratinocytes in lesional skin of psoriasis and atopic dermatitis (AD) and it is considered to be an important initiator of leucocyte/keratinocyte interactions in skin inflammation.	9749989
Hodgkin Disease	Altered Intercellular Communication	Although uncontrolled confounding might have affected our results, they do not indicate that hormonal or immunological changes associated with childbearing play a role in the development of Hodgkin's disease.	9752994
Cataract, Inflammation	Altered Intercellular Communication	Comparative effects of ketorolac 0.5% or diclofenac 0.1% ophthalmic solutions on inflammation after cataract surgery.	9754191
Inflammation, Toxic effect	Altered Intercellular Communication	Objective (Kowa FC 1000 laser cell and flare meter) and subjective (slit-lamp biomicroscope) measurements of inflammation and toxicity were made and compared at three separate post-operative visits.	9754191
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	There was a decrease in histological inflammation and activity in the antrum already during treatment in the OA group, but the decrease did not discriminate for successful treatment.	9754775
Airway structure, Asthma	Altered Intercellular Communication	In 38 asthmatic subjects, changes in clinical symptoms, respiratory function and airway inflammation detected with hypertonic saline induced sputum, and airway reactivity to histamine were investigated.	9756188
Inflammatory abnormality of the eye, Traumatic injury, Eye Neoplasms	Altered Intercellular Communication	The relative frequency of trauma and ocular inflammation as a cause of enucleation decreased significantly (p < 0.05) over the time of the study period while the relative proportion of ocular neoplastic processes increased (p < 0.0001).	9756437
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	The presence of IL-12 p70 protein in the synovial membranes of patients with RA and OA suggests that IL-12 may play an important immunoregulatory role in these diseases by perpetuating inflammation.	9756640
malignant syndrome nos	Altered Intercellular Communication	The imbalance of neurotransmitters and receptors in the central autonomic nervous system may participate in the development of neuroleptic malignant syndrome.	9757468
Communicable Diseases, Inflammation, Hyperviscosity	Altered Intercellular Communication	Hyperviscosity of bronchial secretions mainly depend on their high DNA content, as a result of degradation of polymorphonuclear neutrophils mobilized by infection and inflammation.	9759155
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide (NO) may be a marker of airway inflammation.	9759158
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	Discriminating allergy from nonspecific inflammation has become of striking importance for diagnosis and treatment.	9759406
Disorder of the optic nerve, Orbital Pseudotumor	Altered Intercellular Communication	Thirteen patients underwent surgery for severe orbital inflammation or optic neuropathy and 31 for cosmetic rehabilitation.	9759438
Villous atrophy	Altered Intercellular Communication	Small-bowel mucosal inflammation in reticulin or gliadin antibody-positive patients without villous atrophy.	9759950
Celiac Disease, Inflammatory disease of mucous membrane	Altered Intercellular Communication	We investigated whether individuals with positive coeliac disease antibodies but without small-bowel villous atrophy have mucosal inflammation implicating gluten-sensitivity.	9759950
Presenile dementia, Circadian Rhythms	Altered Intercellular Communication	Dementia has been associated with circadian rhythm disturbances expressed in several dimensions including body temperature, hormonal concentrations, sleep and wakefulness patterns, and rest-activity cycles.	9760668
Inflammation	Altered Intercellular Communication	Neovascularisation is the principal vascular response in chronic inflammation and concomitant fibrotic process.	9760788
Inflammation, Dental Plaque	Altered Intercellular Communication	Of the sites 82% were plaque free, and 96.8% showed no signs of inflammation.	9760897
Ulcerative Colitis	Altered Intercellular Communication	Previous uncontrolled reports have suggested that appendiceal inflammation may occur as a discontinuous lesion in ulcerative colitis.	9762551
Colon Carcinoma, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	The prevalence of appendiceal inflammation in ulcerative colitis (24/50, 48%), was higher than in colonic carcinoma (5/65, 8%, P < 0.001), but was similar to that in Crohn's disease (14/27, 52%).	9762551
Colon Carcinoma, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	Appendiceal inflammation with caecal sparing was seen in nine out of 24 specimens with ulcerative colitis (37%), two out of nine (22%) with Crohn's disease and five out of 65 (8%) with colonic carcinoma.	9762551
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Acute appendicitis NOS (disorder), Crohn Disease	Altered Intercellular Communication	Inflamed appendixes from patients with inflammatory bowel disease showed histological features typical of ulcerative colitis and Crohn's disease rather than acute appendicitis and were significantly less likely to have transmural inflammation.	9762551
Crohn Disease, Colonic Diseases, Ulcerative Colitis, Acute appendicitis NOS (disorder)	Altered Intercellular Communication	In ulcerative colitis, as in Crohn's disease, appendiceal inflammation commonly occurs as a skip lesion and histologically resembles the colonic disease rather than acute appendicitis.	9762551
Communicable Diseases, Inflammation, Breast Carcinoma	Altered Intercellular Communication	Eight percent reported episodes of infection or inflammation at some point since the diagnosis of breast carcinoma.	9762937
Communicable Diseases, Inflammation, Chest wall structure	Altered Intercellular Communication	The frequency of inflammation or infection in patients treated with radiation to the breast or chest wall after an axillary lymph node dissection may be greater than previously appreciated.	9762937
Inflammation, Blepharoptosis	Altered Intercellular Communication	The unilateral ptosis most likely resulted form localized inflammation and the physical presence of the soft contact lens.	9763140
Inflammation, Dental Plaque	Altered Intercellular Communication	In GCF, sICAM-1 levels were higher for patients with plaque (p=0.04) and for patients with inflammation (p=0.02), but did not correlate with disease classifications.	9763331
Inflammation, Dental Plaque	Altered Intercellular Communication	These results suggest that elevated GCF sICAM-1 levels may represent increased shedding of this molecule in the interstitial fluid as a result of membrane-bound ICAM-1 upregulation on ICAM-1 gingival-bearing cells in relation with plaque accumulation and inflammation.	9763331
Congenital MeSH qualifier	Altered Intercellular Communication	MRI in a 17-year-old boy with known congenital agammaglobulinaemia (CA) demonstrated signs of chronic leptomeningeal inflammation with thickened, enhancing meninges.	9763340
Ischemia, Inflammation, Neoplasms, Migraine Disorders, Infarction, Swelling	Altered Intercellular Communication	Although there are numerous causes of gyral swelling and enhancement, such as infarction and neoplasm, if these conditions are reversible and correspond to clinical findings, then the differential diagnosis is narrowed to postictal change, reversible ischemia, complicated migraine, or resolved inflammation/infection.	9763382
Aneurysm, Neoplasms, Swelling, Inflammation	Altered Intercellular Communication	A swelling in the distal thigh may be caused by a tumour of bone or soft tissues, an aneurysm or an inflammation.	9763863
Inflammation	Altered Intercellular Communication	Signs of inflammation may render interpretation more difficult.	9763863
Granulomatous inflammation	Altered Intercellular Communication	T cells are most likely to play an important role in the pathogenesis of WG, and recently a predominant Th1 pattern of immune response has been demonstrated in granulomatous inflammation.	9764612
Inflammation, Acute Cholecystitis	Altered Intercellular Communication	Approximately 20 per cent of laparoscopic cholecystectomies performed for acute cholecystitis require conversion to open cholecystectomy because of severe inflammation.	9764700
Inflammation, Acute Cholecystitis	Altered Intercellular Communication	Laparoscopic subtotal cholecystectomy is a safe and effective alternative to conversion to open cholecystectomy for severe inflammation associated with acute cholecystitis.	9764700
Inflammation	Altered Intercellular Communication	Repeat CSF examination after 10 days showed merely minimal residual changes of inflammation.	9765607
Inflammation	Altered Intercellular Communication	This rare form of chronic inflammation and destruction of the anterior pituitary gland is discussed.	9766156
Coronary Artery Disease, Ventricular Dysfunction, Heart failure	Altered Intercellular Communication	Cardiac natriuretic peptides for diagnosis and risk stratification in heart failure: influences of left ventricular dysfunction and coronary artery disease on cardiac hormonal activation.	9767358
Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	A group of 28 SIRS patients (13 survivors/15 non-survivors) was compared with a healthy control group and with patients with local inflammation.	9767363
Primary malignant neoplasm, Chronic inflammation	Altered Intercellular Communication	We studied IL-6 and other cytokines to determine if they regulate serum APP levels in the same way under the condition of the aberrant, long-lasting 'acute-phase response' that occurs in patients with chronic inflammation and cancer.	9767364
Cancer-related fatigue, Inflammation	Altered Intercellular Communication	We also found that an ongoing inflammation stimulates ob gene expression in patients with CRF.	9767543
Airway structure, Diffuse panbronchiolitis, Bronchiolitis	Altered Intercellular Communication	Expectoration of mucus is important in preventing the development of airway inflammation in patients with diffuse panbronchiolitis (DPB).	9767617
Inflammation	Altered Intercellular Communication	The inflammation was controlled with intravitreal, subconjunctival, topical, and systemic antibiotics.	9768410
Airway structure	Altered Intercellular Communication	Severity of airflow limitation is associated with severity of airway inflammation in smokers.	9769292
Inflammation, Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	In 8 of 12 cases the pathologic lesions consisted of both cellular interstitial inflammation and fibrosis, whereas only cellular inflammation was present in three cases, and fibrosis in one.	9769293
Sialadenitis, Inflammation	Altered Intercellular Communication	In right of this case, we conclude that since management of sialoadenitis depends on the stage of inflammation scintigraphic findings should be interpreted together with radiology and FNAB findings if necessary.	9770717
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	Anti-E-selectin imaging with radiolabelled monoclonal antibody identified areas of inflammation in Crohn's disease and ulcerative colitis.	9771404
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	The data suggest that the epithelium is the major source of iNOS activity in ulcerative colitis and that IL-13 and IL-4 may act as intrinsic regulators of NO generation in intestinal inflammation.	9771406
Pain Distress Question, Pancreatitis, Inflammation, Epigastric	Altered Intercellular Communication	A 61-yr-old alcoholic man complaining of epigastric and back pain was diagnosed as having groove pancreatitis based on the presence of inflammation in the pancreatic head and its extension to the duodenal mucosa with an associated elevated serum amylase level.	9772067
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Mast cells are involved in chronic inflammation and tissue fibrosis.	9774120
Sepsis, Inflammation, Bacterial Infections	Altered Intercellular Communication	C-reactive protein (CRP) proves to be a good marker protein in inflammation due to sepsis; its synthesis is directly influenced by the cytokines released during the acute phase response of inflammation in bacterial infection.	9775136
Sepsis, Inflammation	Altered Intercellular Communication	The authors propose the hypothesis of a correlation between plasma cholesterol levels and the acute phase response during sepsis, which could be induced by the mediators or effectors of inflammation.	9775136
Inflammation, Mesothelioma, Malignant Childhood Neoplasm	Altered Intercellular Communication	Peritoneal mesothelioma is a rare malignant neoplasm that might be linked to chronic peritoneal inflammation.	9775184
Inflammation, Stanford Cancer Institute	Altered Intercellular Communication	Forty-six SCI patients (75.4%) had a chronic type and 10 SCI patients (16.4%) a subacute type of inflammation.	9776015
Inflammation	Altered Intercellular Communication	Eosinophils, prominent cells in asthmatic inflammation, undergo apoptosis or programmed cell death following deprivation of contact with survival-promoting cytokines such as IL-5 and GM-CSF.	9776585
Inflammation, Urachal diverticulum, Malignant Neoplasms, Neoplasms	Altered Intercellular Communication	Xanthogranulomatous inflammation is associated with malignant neoplasms in the bladder as it is in the kidney and extra-urinary sites, as well as with benign neoplasms and non-neoplastic conditions such as urachal diverticula.	9777386
Fibrosis Assessment, Hepatitis, Liver diseases	Altered Intercellular Communication	The purpose of this study was to elucidate the morphometric changes occurring in hepatic lymphatics in human chronic viral liver diseases and to investigate the relationship between liver fibrosis, liver inflammation, and these changes.	9777944
Inflammation, Rheumatoid Factor, Destruction of tissue	Altered Intercellular Communication	The presence of similar proinflammatory cytokines and cell adhesion molecules in the rheumatoid nodule and synovial membrane suggests that similar pathogenic processes result in the chronic inflammation and tissue destruction in these lesions.	9778219
Inflammation, Lymphocytic infiltration, Fibrosis Assessment, Crohn Disease	Altered Intercellular Communication	The histologic findings of transmural inflammation consisting of lymphocytic infiltration, accumulation of partially hyalinized collagen, and fibrosis in the skip areas from the ileum to the cecum were compatible with Crohn's disease.	9780667
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The usual imaging modalities usually identify abnormalities but may not always differentiate malignancy from other condition such as scar tissue or chronic inflammation.	9781003
Inflammation, Ear Inflammation	Altered Intercellular Communication	In pediatric otitis media, cytokines that correlate with various degrees of inflammation are present in middle ear effusions as inflammatory mediators.	9781987
Inflammation	Altered Intercellular Communication	In the present study, there was no correlation with head and neck malignancy/radiation or the clinical degree of inflammation with the presence of either cytokine.	9781987
Granulomatous inflammation	Altered Intercellular Communication	Histological examination showed elastotic changes with associated granulomatous inflammation.	9782424
Inflammation	Altered Intercellular Communication	Binding of the leukocyte glycoprotein L-selectin to ligands expressed by activated endothelium directs leukocyte recruitment to areas of acute inflammation.	9783608
Pain Distress Question, Arthritis	Altered Intercellular Communication	Other assessments included disability, joint inflammation, pain and the acute-phase response.	9783756
Inflammation	Altered Intercellular Communication	In situ detection of apoptosis at sites of chronic bacterially induced inflammation in human gingiva.	9784521
Inflammation, Squamous metaplasia	Altered Intercellular Communication	Varying degrees of inflammation and squamous metaplasia of the ducts were common in NH.	9785128
Cyst of Bartholins gland duct", Inflammation	Altered Intercellular Communication	NH occurs in younger patients and is often associated with inflammation or obstruction of Bartholin's duct.	9785128
Chronic Obstructive Airway Disease, Bronchitis	Altered Intercellular Communication	Although significant bacterial growth was more frequently found in patients with chronic obstructive pulmonary disease exacerbations and in those with a higher degree of bronchial inflammation, the differences between the two groups of patients were not statistically significant.	9785808
Dysmotility, Inflammation, Autonomic neuropathy	Altered Intercellular Communication	Multiple mechanisms are hypothesized to explain motility disorder, such as visceral autonomic neuropathy, inflammation and loss of contractile proteins of smooth muscle layer of the small intestine.	9785913
Pain Distress Question, Neurogenic Inflammation, SLC22A5 gene, Vaso-Occlusive Crisis, Anemia, Sickle Cell	Altered Intercellular Communication	As a mediator of neurogenic inflammation and pain, we hypothesized that levels of the neuropeptide Substance P (SP) would be elevated in patients with sickle cell disease (SCD) with vaso-occlusive pain crisis.	9787150
Pain Distress Question, Inflammation, SLC22A5 gene	Altered Intercellular Communication	These results imply that SP plays a prominent role in the pain and inflammation of SCD and may be a measurable laboratory marker of vaso-occlusive crisis.	9787150
Inflammation	Altered Intercellular Communication	Thus, during the acute phase of inflammation, HDL may be altered to an atherogenic state due to a decrease in LCAT and PON activities.	9790313
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Therefore, this longitudinal analysis was carried out to determine whether HDL function is modified in a single episode of inflammation and thus may contribute to the occurrence of atherosclerotic disease in patients with chronic or recurrent acute inflammation.	9790313
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Fibrosis and portal inflammation were statistically more frequent in group A 1 year after transplantation.	9791153
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	In this study we investigated whether smoking and chronic obstructive pulmonary disease (COPD), both characterized by airway inflammation with increased levels of inflammatory mediators, affect GR characteristics in cultured human bronchial epithelial cells (HBEC).	9792338
Inflammation	Altered Intercellular Communication	This may result from the inflammation found in the airways from smokers.	9792338
Inflammation, Thyroiditis	Altered Intercellular Communication	MSI was detected neither in patients with severe inflammation nor in the absence of thyroiditis.	9792998
Rheumatoid Arthritis, Keratitis	Altered Intercellular Communication	Areactive forms of keratitis in patients with seropositive rheumatoid arthritis are inflammations threatening the visual acuity and integrity of the eye.	9793383
Neoplasms	Altered Intercellular Communication	It is usually associated to chronic inflammatory conditions, but rarely it can hide a tumour.	9793402
Inflammation, Affection	Altered Intercellular Communication	According to the CT images, 11 of them had affected maxillary sinuses and ethmoidal labyrinth cells, 15 had inflammation in the sphenoid sinuses alone or in combination with affection of the other sinuses.	9793426
Inflammation, Necrosis	Altered Intercellular Communication	Histopathological examination of the irradiated SCC revealed dermal keratin pearls and keratinocytic necrosis resembling apoptosis as well as inflammation and foreign body giant cell reaction.	9793520
Psychogenic	Altered Intercellular Communication	The cause may be vascular, neurogenic, hormonal, drug-related, psychogenic, or a combination thereof.	9793543
Unspecified visual loss, Inflammation, Endophthalmitis, Choroidal Detachment	Altered Intercellular Communication	The clinical diagnosis of sympathetic ophthalmia was made after a second inflammation course with substantial visual loss and subtotal chorioidal detachment.	9793917
Inflammation, Hemorrhage	Altered Intercellular Communication	Magnetic resonance imaging disclosed a space-occupying lesion resembling an old hemorrhage or an inflammation.	9793918
Inflammation, Hypertrophy	Altered Intercellular Communication	Nerve root inflammation and enlargement was seen in 36% of the images, corresponding to an operative finding of 32%.	9795811
Acute inflammation	Altered Intercellular Communication	Secondary closure of posterior continuous curvilinear capsulorhexis in normal eyes and eyes at risk for postoperative inflammation.	9795847
Cataract, Acute inflammation	Altered Intercellular Communication	To observe the posterior continuous curvilinear capsulorhexis (PCCC) after cataract surgery in control eyes and eyes with an increased risk for postoperative inflammation.	9795847
Inflammation, Diabetes Mellitus, Uveitis, Retinitis Pigmentosa, Acute inflammation	Altered Intercellular Communication	After phacoemulsification, a PCCC was performed before intraocular lens (IOL) implantation in 20 eyes of 18 patients with ocular or systemic conditions that predisposed them for increased postoperative inflammation; e.g., diabetes, uveitis, retinitis pigmentosa (inflammation group).	9795847
Pain Distress Question, Inflammation, Temporomandibular Joint, Myalgia, Trigeminal Neuralgia, Dentin Sensitivity, Hemangioma	Altered Intercellular Communication	The disorders included temporomandibular joint (TMJ) pain, trigeminal neuralgia, muscular pain, aphatae, inflammation, and tooth hypersensitivity postoperatively and in small hemangiomas.	9796491
Inflammation, Carditis	Altered Intercellular Communication	In contrast, H. pylori was demonstrated in gastric tissue samples (either from the cardia or distally) of patients with carditis, with the prevalence rate increasing with greater degrees of cardiac inflammation.	9796721
Carditis, Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	These findings suggest that carditis with histologic features similar to those of gastritis in the distal stomach was a sequel of H. pylori infection and represented a part of an H. pylori--associated gastric inflammation.	9796721
Gingivitis, Inflammation, Reduction (chemical), Dental Plaque	Altered Intercellular Communication	Gingivitis values corresponded well with the values of dental plaque; the same pattern with a clear reduction in gingivitis score was seen in all age groups between 1973 and 1983, and an increase in the mean frequency of gingival inflammation between 1983 and 1993 was seen in the 20-year age group.	9797053
Inflammation	Altered Intercellular Communication	Increased salivary HA concentrations can serve as a marker of local inflammation and may be of value in the diagnosis of SS.	9797560
Pain Distress Question, Inflammation, Disease remission, Daytime, Damage	Altered Intercellular Communication	The occurrence of night pain characterised those with more active disease and night pain VAS measurement correlated best with measures of joint inflammation whereas daytime pain scores, both at rest and on movement, seemed influenced by the degree of permanent joint damage.	9797572
Inflammatory abnormality of the eye	Altered Intercellular Communication	These results indicate strong association of delayed tear clearance with intrinsically and extrinsically generated ocular surface inflammation.	9797670
Inflammation	Altered Intercellular Communication	The presence of delayed tear clearance may set up a vicious cycle to aggravate the existing inflammation.	9797670
Chronic Obstructive Airway Disease, Bronchitis	Altered Intercellular Communication	Inhaled corticosteroids reduce neutrophilic bronchial inflammation in patients with chronic obstructive pulmonary disease.	9797758
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Airways inflammation is a feature of chronic obstructive pulmonary disease (COPD), but the role of corticosteroids in the management of clinically stable patients has yet to be established.	9797758
Cataract, Inflammation	Altered Intercellular Communication	A clinical evaluation of diclofenac-gentamicin combination eye drops in the control of inflammation after cataract surgery.	9798189
Inflammation, Oral Manifestations, Crohn Disease	Altered Intercellular Communication	Deep stromal inflammation--a possible new ocular manifestation of Crohn's disease.	9798196
Inflammatory Bowel Diseases, Crohn Disease, Keratitis	Altered Intercellular Communication	Crohn's disease, an inflammatory bowel disease, is infrequently associated with epithelial and subepithelial corneal inflammation.	9798196
Inflammation, Crohn Disease	Altered Intercellular Communication	However, deep stromal inflammation has not been described previously in association with Crohn's disease.	9798196
Inflammation, Uveitis	Altered Intercellular Communication	We report on a 52-year-old male who suffered from anterior uveitis and deep stromal inflammation.	9798196
Crohns disease of large bowel", Inflammatory abnormality of the eye	Altered Intercellular Communication	Complete ocular and systemic workup revealed an active asymptomatic Crohn's colitis; no other possible cause for the ocular inflammation was found.	9798196
Inflammation, Keratitis, Crohn Disease	Altered Intercellular Communication	We conclude that deep stromal inflammation, in addition to the previously reported corneal epithelial inflammation, may be associated with Crohn's disease.	9798196
Inflammation, Kidney Diseases	Altered Intercellular Communication	Tenascin is a large oligomeric glycoprotein component of the extracellular matrix that increases rapidly after inflammation or injury, suggesting that it may be an indicator of renal disease activity.	9799064
Communicable Diseases, Hemorrhage, Inflammation, Injury of large intestine	Altered Intercellular Communication	Principles of management include inspection of the percutaneous nephrostolithotomy tract for colonic injury whenever the tract is inspected for bleeding, high index of suspicion for colonic injury when a patient develops unexplained signs or symptoms of inflammation or infection postoperatively, and prompt, assured drainage of both the colon and urinary collecting system.	9800900
Inflammation, Tumor necrosis	Altered Intercellular Communication	To provide an objective measure of inflammation in the genital tract, we measured levels of the proinflammatory cytokines, tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta) in the semen of men with chronic prostatitis/chronic pelvic pain syndrome and compared these with levels in normal men.	9801092
Inflammation	Altered Intercellular Communication	This suggests that inflammation of the genital tract is a feature of this disease, irrespective of the presence or absence of leukocytes in the expressed prostatic secretions.	9801092
Metaplastic, Inflammation, Traumatic injury, Nephrogenic metaplasia	Altered Intercellular Communication	Nephrogenic adenoma is a benign metaplastic lesion of the urinary bladder, reported to occur as a response to inflammation, trauma, intravesical therapies, and after renal transplantation.	9801094
Conn Syndrome, Adrenal hyperplasia	Altered Intercellular Communication	Hormonal characteristics of primary aldosteronism due to unilateral adrenal hyperplasia.	9801995
Adrenal hyperplasia	Altered Intercellular Communication	Unilateral adrenal hyperplasia involving the zona glomerulosa rarely has been reported, with varying and incompletely characterized hormonal characteristics.	9801995
Inflammation	Altered Intercellular Communication	They also indicate that only macrophages may have a clinical relevance in disc tissue inflammation.	9802155
Inflammation	Altered Intercellular Communication	Histologically, 8 patients had a mixed inflammatory infiltrate, 4 had predominantly neutrophilic inflammation, and 2 had predominantly lymphocytic inflammation.	9802347
Inflammation, Primary malignant neoplasm, Colorectal Carcinoma, Colitis	Altered Intercellular Communication	Some investigators suggest that patients with extensive colitis have a genetic predisposition to CRC and that long-standing inflammation is not of primary importance in the promotion of cancer.	9802447
Gingivitis	Altered Intercellular Communication	Association of oxygen tension in human periodontal pockets with gingival inflammation.	9802712
Liver carcinoma, Liver Cirrhosis	Altered Intercellular Communication	In hepatocellular carcinoma, the underlying cirrhosis may account for most hormonal and metabolic changes although cyclic guanosine 3',5'-monophosphate increases could also be due to the neoplastic process per se.	9804395
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	The role of allergy and the severity of inflammation where assessed by a systematic exploration, which combined a detailed allergy evaluation and blood and lacrimal sampling.	9805681
Conjunctivitis	Altered Intercellular Communication	Interpretation of biological parameters evidencing conjunctival inflammation is more difficult.	9805681
Inflammation, Affection	Altered Intercellular Communication	Low-grade forms of the affection may be discovered lately on a recurrence of the inflammation following any event as an ocular surgical procedure.	9805688
Inflammation	Altered Intercellular Communication	[Chronic pseudo-tumor inflammation of the eyelid induced by reaction to a non-resorbable suture.	9805691
Cessation of life, Inflammation, Bronchitis, Chronic	Altered Intercellular Communication	A study of 161 Los Angeles County residents aged 12-28 years old who had died sudden violent deaths showed frequent and severe chronic glandular bronchitis (CGB), that is to say grade > or =5 (0-10) chronic inflammation involving at least one, half or more, and all submucosal glands in 53.4%, 21%, and 4.4% of the main stem bronchi, respectively.	9808436
Inflammation, Pseudomonas Infections	Altered Intercellular Communication	Despite killing of > 10(6) cfu/ml of bacteria within ten minutes in vitro and in vivo, it was not possible to eradicate the Pseudomonas infection obviously caused by inflammation of the upper urinary tract and perpetuated by intravesical concrements.	9809403
Inflammation, Myocarditis, CTCAE 5.0, Myocytes, Cardiac	Altered Intercellular Communication	Antimyosin scintigraphy and immunohistologic analysis of endomyocardial biopsy in patients with clinically suspected myocarditis--evidence of myocardial cell damage and inflammation in the absence of histologic signs of myocarditis.	9809950
Myocarditis	Altered Intercellular Communication	Recently developed immunohistologic techniques appear to be more sensitive for the detection of myocardial inflammation than histologic analysis alone.	9809950
Myocarditis	Altered Intercellular Communication	Histologic analysis of the endomyocardial biopsy alone is often negative, but additional immunohistologic analysis of the endomyocardial biopsy frequently provides evidence of myocardial inflammation in these patients.	9809950
Inflammation, Dry skin	Altered Intercellular Communication	Since birth, he suffered from dry skin and inflammation of the eyelids.	9810924
Inflammation	Altered Intercellular Communication	Quantification of synovistis by MRI: correlation between dynamic and static gadolinium-enhanced magnetic resonance imaging and microscopic and macroscopic signs of synovial inflammation.	9811140
Inflammation, Arthritis, Synovitis	Altered Intercellular Communication	Dynamic and static gadolinium-diethylenetriaminepentaacetic acid(Gd-DTPA)-enhanced magnetic resonance imaging (MRI) were evaluated as measures of joint inflammation in arthritis, by a comparison with macroscopic and microscopic signs of synovitis.	9811140
Inflammation	Altered Intercellular Communication	Macroscopic and microscopic synovial inflammation as well as nine histologic tissue characteristics were graded at four preselected biopsy sites.	9811140
Inflammation	Altered Intercellular Communication	The rate of early enhancement of the total synovial membrane of the preselected slice, determined by dynamic MRI, was highly correlated with microscopic evidence of active inflammation (Spearman p = 0.73; p < 10(-7).	9811140
Inflammation	Altered Intercellular Communication	Dynamic MRI could distinguish knees with and without synovial inflammation with a high predictive value (0.81-0.90).	9811140
Inflammation	Altered Intercellular Communication	Moderate and severe inflammation could not be differentiated.	9811140
Inflammation	Altered Intercellular Communication	The early enhancement rate was correlated with histologic features of active inflammation, particularly vessel proliferation and mononuclear leucocyte infiltration.	9811140
Inflammation	Altered Intercellular Communication	Dynamic evaluation of small synovial sections at the biopsy sites and static spin-echo MRI resulted in considerably weaker correlations to histologic inflammation than dynamic evaluation of the total synovium.	9811140
Inflammation	Altered Intercellular Communication	The optimal time for enhancement measurements was one-half to one minute after Gd injection, as the highest correlation coefficients to histologic inflammation were observed in this interval.	9811140
Inflammation	Altered Intercellular Communication	Dynamic MRI can be used to determine synovial inflammation.	9811140
Arthritis	Altered Intercellular Communication	Evaluation of large synovial areas one-half to one minute after Gd injection best reflects joint inflammation.	9811140
Inflammation, Electrocardiogram: myocardial infarction (finding), Angina Pectoris, Atherosclerosis	Altered Intercellular Communication	Examination of atherogenic, hemostatic, inflammation, and genetic variables in the clinically quiescent state permitted no distinction between subjects with a previous isolated myocardial infarction in contrast to those with long-standing uncomplicated stable angina, favoring the notion that acute coronary events occur at random on a varying background of atherosclerosis.	9812085
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	These data demonstrate a positive association between serum CAMs with carotid IMT and further support the hypothesis that systemic inflammation may have a role in atherosclerotic lesion development.	9812916
Airway structure, Dermatitis, Atopic, Asthma	Altered Intercellular Communication	Cetirizine has several antiallergic properties that suggest a potential effect on the development of airway inflammation and asthma in infants with atopic dermatitis.	9814724
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	CM101 is a bacterial polysaccharide that induces neovascular inflammation in malignant tumors.	9815693
Saint Lucia, Hepatitis, Chronic, Cirrhotic, FAM126A gene	Altered Intercellular Communication	The findings from the three case-control studies indicate that type 1b infection is more closely associated with the development of LC and HCC than type 2a or 2b through its role in the progression of chronic liver inflammation to a cirrhotic stage.	9816816
Diarrhea, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Thus, three patients with diarrhoea lasting 1 year or less showed only minimal or irregularly thickened mucosal folds, which seemed to result from mucosal inflammation.	9817096
Inflammation, Bronchiectasis	Altered Intercellular Communication	In conclusion, patients with bronchiectasis in a stable phase have raised systemic markers of inflammation.	9817152
Inflammation, Hyperplasia	Altered Intercellular Communication	In the 7 patients with positive CK-20 histology showed chronic inflammation in 2, atypical hyperplasia in 3 and metaplasia in 1.	9817302
Pulmonary Surfactants, Pulmonary Embolism, Inflammation	Altered Intercellular Communication	In conclusion, pulmonary embolism is associated with alterations in lung surfactant and inflammation in lung tissue, expressed by an increase in PAF and in neutrophils.	9817700
Inflammation, MS4A2 wt Allele	Altered Intercellular Communication	Airways inflammation, atopy, and (1--> 3)-beta-D-glucan exposures in two schools.	9817726
Airway structure	Altered Intercellular Communication	The results suggest that (1--> 3)-beta-D-glucan, either by itself or as an indicator of molds, is a risk indicator of airways inflammation.	9817726
Acute inflammation	Altered Intercellular Communication	Double-masked, placebo-controlled evaluation of loteprednol etabonate 0.5% for postoperative inflammation.	9818338
Inflammation	Altered Intercellular Communication	Subclinical extension of viral inflammation into the CNS occurs commonly in HZ.	9818869
Inflammation, Neoplasms	Altered Intercellular Communication	Nine of 20 baseline biopsies showed chronic inflammation; six with lymphocytic tumor infiltration and three where inflammation was confined to the perivascular/peritumoral spaces.	9819796
Inflammation, Musculoskeletal torsion, function	Altered Intercellular Communication	Usually, acute scrotum in infants is due to torsion, but there are reasons to believe that primary inflammation occurs more often than supposed.	9820007
Inflammation, Edema	Altered Intercellular Communication	In this case, the underlying cause of the neurological symptoms was most likely an infiltration of the right lumbosacral nerve caused by edema and inflammation of the terminal ileum in the vicinity of the presacral space.	9820424
Necrotizing granulomatous inflammation, Fibrosis Assessment, Subarachnoid Hemorrhage, Vascular Invasion Assessment, Arteritis, Candidiasis	Altered Intercellular Communication	This uncommon manifestation of candidiasis was accompanied by basilar granulomatous inflammation and fibrosis of meninges with arteritis, vascular invasion by fungi, and terminal subarachold hemorrhage.	9822135
Granulomatous inflammation, Diverticulitis of sigmoid colon	Altered Intercellular Communication	Granulomatous inflammation in sigmoid diverticulitis: two diseases or one?	9822925
Granulomatous inflammation, acute diverticulitis	Altered Intercellular Communication	Eight patients (median age 64 years, four males) whose sigmoid colectomy specimens showed acute diverticulitis and granulomatous inflammation were identified.	9822925
Granulomatous inflammation, Diverticulitis of sigmoid colon	Altered Intercellular Communication	Granulomatous inflammation appears to be part of a spectrum of sigmoid diverticulitis.	9822925
Squamous cell carcinoma of conjunctiva, Intraocular inflammation, Choroidal Detachment	Altered Intercellular Communication	An 89-year-old woman with recurrent conjunctival mucoepidermoid carcinoma developed intraocular inflammation and an elevated fundus lesion that simulated choroidal detachment in her affected right eye.	9823358
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	There is evidence of a relationship between inflammation and cancer growth and spread.	9823802
Inflammation, Pituitary Adenoma	Altered Intercellular Communication	Our finding of lymphocytic inflammation in pituitary adenomas that have undergone an apoplectic event may suggest at least a modest immune-mediated response to damaged anterior pituitary tissue.	9824104
Hepatitis	Altered Intercellular Communication	Histologically, soluble Fas antigen levels showed correlation with the levels of liver inflammation (p<0.01).	9824259
Hepatitis, Chronic, Hepatitis	Altered Intercellular Communication	These findings suggest that serum soluble Fas antigen may reflect the expression levels of Fas antigen on hepatocytes and the severity of liver inflammation in chronic hepatitis C.	9824259
Inflammation, Diarrhea	Altered Intercellular Communication	Such an effect of ETBF derived BFT on epithelial cells in the colon in vivo would be expected to lead to mucosal inflammation and diarrhoea.	9824346
Airway structure, Asthma	Altered Intercellular Communication	Though direct measurement of endogenous NO has been difficult in humans, we have recently found that measurement of NO derivatives in induced sputum may be useful for assessing airway inflammation in asthmatic patients.	9824391
ARCN1 gene, Asthma, Airway structure	Altered Intercellular Communication	We conclude the increased production of endogenous NO in patients with asthma and COPD, and that NO derivatives in induced sputum are more valuable than exhaled NO in assessing airway inflammation in patients with COPD.	9824391
Inflammation	Altered Intercellular Communication	The frequency with which non-steroidal anti-inflammatory drugs (NSAIDs) increase small intestinal permeability and cause inflammation is uncertain.	9824578
Gastrointestinal inflammation, Intestines, Small	Altered Intercellular Communication	All the conventional NSAIDs studied were equally associated with small intestinal inflammation apart from aspirin and nabumetone which seem to spare the small bowel.	9824578
Inflammation, Anemia	Altered Intercellular Communication	Activation of CD4+ and CD8+ T-lymphocytes in bone marrow associated with reduced erythropoiesis in patients with chronic inflammation and anaemia.	9824895
Cessation of life	Altered Intercellular Communication	In this case, sudden death could also be considered arrhythmogenic in relation to the additional workload by persistent hormonal stimulation.	9824991
Pheochromocytoma, Adrenal Gland Pheochromocytoma	Altered Intercellular Communication	The diagnosis of phaeochromocytoma was proposed despite the negative hormonal assessment and was supported by positive MIBG scintigraphy, compatible with bilateral adrenal phaeochromocytoma with no other sites.	9827197
Inflammation, Bronchial Hyperreactivity	Altered Intercellular Communication	Bronchial hyperresponsiveness to UNDW can then be considered an effective reflection of the existence of underlying inflammation of the airways.	9827426
Inflammation, Disorder characterized by fever, Fever, CTCAE, Pain Distress Question	Altered Intercellular Communication	Aortic dissection may then present as a prolonged febrile illness with fever and/or inflammation as main symptoms, with little or no pain.	9827441
Intraocular inflammation	Altered Intercellular Communication	Recurrent bleb infection was defined as at least two episodes of bleb purulence with or without associated intraocular inflammation separated by a quiescent period of at least 3 months.	9828779
Airway structure, Bronchiectasis, Neutrophilia (finding)	Altered Intercellular Communication	Airway inflammation in bronchiectasis is characterised by tissue neutrophilia, a mononuclear cell infiltrate composed mainly of CD4+ T cells and CD68+ macrophages, and increased IL-8 expression.	9828857
Necrosis with inflammation	Altered Intercellular Communication	Pathologic specimens obtained from the abscess wall revealed necrotic inflammation and wide, nonseptate hyphae with right angle branching, which are typical characteristics of the family Mucoraceae.	9830284
Pain Distress Question, Inflammation, Headache, hyperthermia treatment	Altered Intercellular Communication	Clinical manifestations have a low to moderate intensity and consist in local pain and inflammation, sometimes associated with headache and hyperthermia.	9830723
Inflammation, Angina, Unstable	Altered Intercellular Communication	Systemic markers of inflammation have been found in unstable angina.	9832480
Inflammation	Altered Intercellular Communication	These data support the hypothesis that circulating forms of adhesion molecules have an immunomodulatory function and can intervene in islet inflammation.	9833936
Inflammation, Carcinogenesis, Ulcerative Colitis	Altered Intercellular Communication	The diversity of the early changes suggests that the recurrent inflammation characteristic of long-standing UC randomly damages genes known to participate in colon carcinogenesis and that it affects multiple target genes.	9834286
Inflammation	Altered Intercellular Communication	The histopathology of a minute specimen was interpreted as consistent with chronic inflammation in a cyst wall.	9840143
Inflammation, Hypocholesterolemia	Altered Intercellular Communication	Studies with recombinant TNF also confirm the role of TNF in hypocholesterolemia in inflammation.	9840652
Inflammation, Fever, CTCAE	Altered Intercellular Communication	MIP-1alpha and MIP-1beta increase during acute inflammation but are not associated with fever in endotoxemic humans during cyclooxygenase blockade.	9841832
atherosclerotic	Altered Intercellular Communication	The level of monocytes is indicative of an inflammatory condition and of leukocytes of an atherosclerotic inflammatory process.	9842195
Gluten, Gastrointestinal symptom	Altered Intercellular Communication	Some individuals with genetic susceptibility to the disease have serological evidence of gluten sensitivity without overt gastrointestinal symptoms or evidence of small-bowel inflammation.	9843103
Bronchial brand of guaifenesin-theophylline, Interstitial thickening, Ground Glass Opacity, Abnormally opaque structure (morphologic abnormality), Interstitial inflammation, Fibrosis Assessment	Altered Intercellular Communication	Areas of ground-glass opacity with or without irregular linear opacity or bronchial dilatation on CT corresponded pathologically to areas of interstitial thickening caused by varying degrees of interstitial inflammation and fibrosis showing temporal uniformity.	9843306
Interstitial thickening, Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	These areas represent interstitial thickening caused by varying degrees of interstitial inflammation, fibrosis, or both.	9843306
Inflammation, Periodontitis	Altered Intercellular Communication	Periodontitis is a very frequent, chronic recurrent, unspecific bacterial inflammation of the periodontium that arises in accumulated plaques on the teeth at the gingiva.	9844265
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation destructing retina and numerous acid-fact bacilli were found in histologic examination of the resected eye.	9844347
Tunnel Clusters, Inflammation, Endometrial Hyperplasia, Necrosis	Altered Intercellular Communication	Four patients had false-positive findings; the hyperintense lesion on posttreatment MR images was due to a tunnel cluster pattern (focal hyperplasia of the endocervical glands with inflammation) in three patients and necrosis in one patient, without any evidence of neoplastic tissue.	9844681
Inflammation, Neoplasms, Edema, RECIL MR, Parametrial	Altered Intercellular Communication	Involvement of three parametrial halves and five fornices was overestimated at MR, because edema or inflammation was not distinguishable from tumor.	9844681
Nasal inflammation, Chronic osteomyelitis	Altered Intercellular Communication	Unenhanced computed tomography also revealed widespread nasal inflammation and an abnormal soft tissue mass anterior to the maxilla consistent with chronic osteomyelitis.	9846466
Airway structure, Asthma, Bronchitis	Altered Intercellular Communication	This study shows that airway inflammation in asthma and chronic bronchitis is associated with an imbalance between MMP-9 and TIMP-1 which may have a role in the pathogenesis of ECM remodeling and airflow obstruction.	9847290
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic airways inflammation is one of the features of chronic obstructive pulmonary disease (COPD).	9847291
Inflammation	Altered Intercellular Communication	A cyclocryotherapy-induced intense inflammation was seen more frequent in NVG (43.2%) than in nNVG (17.9%).	9848066
Inflammation, Fibrosis Assessment, Edema, Muscle hypertrophy	Altered Intercellular Communication	In the remaining specimens, the ligament showed mucoid change (17.5%), amyloid deposits (7.8%), inflammation (3.0%), and chondrometaplasia (2.4%), and the tenosynovium showed fibrosis (25.3%), edema (7.2%), inflammation (10.2%), amyloid deposits (8.4%), and vascular hypertrophy (4.8%).	9848552
Hypercholesterolemia, Inflammation	Altered Intercellular Communication	These data suggest that elevated plasma LDL levels in conditions such as hypercholesterolemia enhance monocyte CCR2 expression and chemotactic response and potentially contribute to increased monocyte recruitment to the vessel wall in chronic inflammation and atherogenesis.	9848893
Refractory anemias, Rheumatoid Arthritis, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	To determine the localisation and level of expression of human type IIa secretory phospholipase A2 (sPLA2) in the synovium of rheumatoid arthritis (RA), osteoarthritis (OA), and non-arthritic (NA) patients and to examine the relation between sPLA2 and histological features of inflammation.	9849315
Inflammation	Altered Intercellular Communication	There was a significant correlation between the sPLA2 staining score and inflammation score within the RA patient group (p < 0.05).	9849315
Inflammation, Bulla, Cicatrization	Altered Intercellular Communication	PBK/ABK corneas were selected to encompass only those with bullae and without inflammation, scarring or neovascularisation.	9850274
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Early effective suppression of inflammation in rheumatoid arthritis reduces radiographic progression.	9851262
Inflammation, Lesion of lung, Neoplasms	Altered Intercellular Communication	A total of 68 patients with lung lesions (tumours and inflammation) underwent both helical computed tomography (CT) and 201Tl SPET examinations.	9853329
Inflammation	Altered Intercellular Communication	Oxygen-derived free radicals are important mediators of inflammation and potential carcinogens.	9855081
Inflammation, Orbital Myositis	Altered Intercellular Communication	Presumed isolated inflammation of the superior oblique muscle in idiopathic orbital myositis.	9855149
Orthodontic, Communicable Diseases, Inflammation	Altered Intercellular Communication	The bone resorption seen here, despite vital tissue in the invagination canal, was probably due to osteoclastic activity caused by a low grade chronic infection, influenced by an injury-induced inflammation in the periodontium during orthodontic treatment.	9855805
Inflammation, Arthritis, Kit Ligand, human	Altered Intercellular Communication	Expression of stem cell factor (SCF) and SCF receptor (c-kit) in synovial membrane in arthritis: correlation with synovial mast cell hyperplasia and inflammation.	9858422
Inflammation, Arthritis, Kit Ligand, human	Altered Intercellular Communication	We investigated expression of SCF and c-kit in synovial membrane with particular reference to the mechanism of local MC hyperplasia and inflammation in arthritis.	9858422
Kit Ligand, human, Hyperplasia	Altered Intercellular Communication	Redistribution of SCF was accompanied by degranulation and/or accumulation of c-kit+ MC, the hyperplasia of which correlated positively with histologic inflammation/inflammatory cell densities, but did not appear to involve MC proliferation in situ.	9858422
Inflammation, Acute vascular insufficiency of intestine (disorder)	Altered Intercellular Communication	It has recently been suggested that inflammation may play an important role in the pathogenesis of acute ischemic syndromes.	9859607
Inflammation	Altered Intercellular Communication	It may therefore be important to relate their clinical features with plasma indexes of inflammation.	9859607
Inflammation, Thrombus	Altered Intercellular Communication	The high blood leukocytes, platelet and fibrinogen levels of Group A patients are consistent with a significant role of inflammation in the pathogenesis of the thrombotic process while hemodynamic and local mechanical factors are probably more important in patients with normal blood leukocytes.	9859607
Communicable Diseases, Rhinitis, Common Cold, Allergic	Altered Intercellular Communication	Rhinitis may be caused by allergic, non-allergic, infectious, hormonal, occupational, and other factors.	9860024
Allergic, Hypothyroidism, Drug Eruptions, Occupational, Common Cold, Rhinitis	Altered Intercellular Communication	The guidelines are comprehensive and begin with statements on clinical characteristics and diagnosis of different forms of rhinitis (allergic, non-allergic, occupational rhinitis, hormonal rhinitis [pregnancy and hypothyroidism], drug-induced rhinitis, rhinitis from food ingestion), and other conditions that may be confused with rhinitis.	9860027
Inflammation, Asthma	Altered Intercellular Communication	Inflammation in asthma is characterized by a Th2 response.	9860244
Inflammation, Asthma	Altered Intercellular Communication	These results show that AM are at least primed for the production of IL-10 and IL-12 in asthma, and suggest that these cells could be involved in the resolution of the asthmatic inflammation.	9860244
Herpes Simplex Infections, Inflammation	Altered Intercellular Communication	There was no evidence of association between HSV or CMV antibodies and plasma concentration of C-reactive protein, a marker of inflammation that predicts vascular risk in this cohort.	9860778
Orthostasis, Hypertension, CTCAE	Altered Intercellular Communication	Hormonal response to orthostasis in elderly people with systemic systolic hypertension.	9861522
Inflammation	Altered Intercellular Communication	These observations suggest that local factors and associated inflammation is essential for onset of the nifedipine-induced gingival hyperplasa.	9863337
Granuloma, Thrombosis, Hemorrhage, Granulomatous inflammation, neurological complication, Vasculitis, CTCAE, Trichinellosis, Hypersensitivity	Altered Intercellular Communication	Several pathogenic mechanisms are responsible for the neurological complications in trichinosis: obstruction of brain blood vessels by larvae, cysts or granulomas, toxic vasculitis with secondary thrombosis and haemorrhages, granulomatous inflammation of the brain parenchyma and allergic reaction.	9863383
Helicobacter pylori, Stomach Carcinoma, Gastritis, Infection caused by Helicobacter pylori, Communicable Diseases	Altered Intercellular Communication	Vitamin C may be protective against gastric cancer though infection with Helicobacter pylori is associated with a reduction in intragastric concentrations of vitamin C. To examine the effects of H pylori infection, gastric juice pH, the severity and extent of gastric inflammation, and CagA antibody status of the individual on gastric juice and mucosal vitamin C concentrations.	9863475
Inflammation	Altered Intercellular Communication	Neutrophilia of infection/inflammation: are we really dealing with "inflamed" leukocytes?	9865459
Inflammation, Avascular necrosis of bone	Altered Intercellular Communication	Histological examination of the papillary muscle showed typical ischemic necrosis without inflammation.	9866347
Inflammation, Specimen Type - Fistula	Altered Intercellular Communication	There was no evidence of inflammation and adherent lymph nodes around the fistula.	9866352
Inflammation, Respiratory Failure	Altered Intercellular Communication	This suggested that the worsening respiratory failure experienced by our patients during their clinical course was a result of such reactions, and that methylpredonisolone was effective as the treatment of inflammation.	9866985
Inflammation, Hypersensitivity	Altered Intercellular Communication	Selected was loteprednol etabonate 0.5%, previously found effective in the treatment of ocular allergy and inflammation.	9867336
Myopathy	Altered Intercellular Communication	In our series of 66 cases, there were 60 benign lesions; of these, 21 were benign masses, 11 were inflammations, and 28 were myopathies.	9868738
Inflammation, Fibrosis Assessment, Hepatitis, Hepatitis B, Chronic	Altered Intercellular Communication	This feature was more frequently present in type C chronic hepatitis with low activity of inflammation and low grade of fibrosis, than with type B chronic hepatitis.	9869392
Inflammation	Altered Intercellular Communication	False-positive fluorescence was associated with microscopic inflammation of the mucosa or feces in the colon.	9869731
Inflammation, Fibrosis Assessment, Cholestasis	Altered Intercellular Communication	At autopsy, the liver exhibited cholestasis, fibrosis extending from the portal tracts, mild inflammation and hepatocytes with a ground-glass appearance.	9870801
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The enhanced and coordinated expression of IL-1beta, TNFalpha, and iNOS by chondrocytes strongly supports the hypothesis that chondrocytes are the major site of production of mediators of inflammation in human OA, thus playing a primary role in the pathogenesis of this disease.	9870873
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To determine whether monocyte/macrophage expression of the CD6 ligand, activated leukocyte cell adhesion molecule (ALCAM) (CD166), is regulated by cytokines during inflammation in rheumatoid arthritis (RA).	9870879
Airway structure, Neoplasms	Altered Intercellular Communication	Intercellular adhesion molecule (ICAM-1), vascular cell adhesion molecule (VCAM-1), and the lymphocyte function-associated antigen (LFA-1) are cell adhesion molecules thought to play an important role in the complex process of airway inflammation and tumor cell growth.	9872650
Acquired Immunodeficiency Syndrome, vascular inflammations	Altered Intercellular Communication	A significant proportion of brain tissue specimens from children with AIDS show evidence of vascular inflammation in the form of transmural and/or perivascular mononuclear-cell infiltrates at autopsy.	9874673
Inflammation, Malignant Neoplasms, Neoplasms, Ischemia	Altered Intercellular Communication	Analysis of mucosa proximal and distal to left-sided cancers showed that this increase was due to a statistically higher frequency of partially involved crypts in proximal mucosa, which probably resulted from the obstructive effects of the tumour causing increased exposure of the proximal mucosa to luminal carcinogens and/or epithelial regeneration in response to low-grade inflammation or ischaemia.	9875137
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Although there is relatively little evidence of inflammation in osteoarthritis (OA), increases in mast cell numbers and mast cell activation are prominent features of the synovial tissue.	9875142
Refractory anemias, Inflammation	Altered Intercellular Communication	Histological analysis demonstrated that the scores for infiltration by lymphocytes and plasma cells, and the scores for inflammation, were significantly higher in RA than in ReA.	9875143
Inflammation, Cryptosporidiosis, Damage	Altered Intercellular Communication	The histologic features (intensity of Cryptosporidium infection, inflammation, mucosal damage, copathogens) of gastrointestinal biopsies from 37 HIV-positive individuals with cryptosporidiosis were systematically graded.	9875584
Inflammation, Cytomegalovirus Infections	Altered Intercellular Communication	The nature and intensity of the inflammatory response varied widely; however, duodenal biopsies from a subset of patients (37%) revealed marked acute inflammation that was associated with concomitant cytomegalovirus infection.	9875584
Inflammation, Nasal Polyps	Altered Intercellular Communication	Azelastine reduces mediators of inflammation in patients with nasal polyps.	9876778
Granulomatous inflammation, Pulmonary hemorrhage	Altered Intercellular Communication	Three nodules were surrounded by halos of ground-glass attenuation, which were shown on histologic examination to represent granulomatous inflammation (in 2 cases) and pulmonary hemorrhage due to a pulmonary artery-bronchial fistula (in 1 case).	9879269
Granulomatous inflammation	Altered Intercellular Communication	Two nodules had adjacent consolidation, which was due to granulomatous inflammation surrounding a necrotizing granuloma.	9879269
Necrotizing granulomatous inflammation, Granulomatous inflammation, Coccidioidomycosis	Altered Intercellular Communication	Necrotizing granulomas in chronic coccidioidomycosis appear as a well-defined nodule on CT, while granulomatous inflammation may appear as areas of ground-glass attenuation or consolidation.	9879269
Inflammation, Nasal Polyps	Altered Intercellular Communication	In nasal polyps constantly associated with chronic inflammation, a dysregulation of epithelial cell proliferation has been described.	9879422
Acute inflammation, Perforation (observation), Chronic disease	Altered Intercellular Communication	Laparotomy and histopathologic examination confirmed the correct indication for surgery in 95.2% of patients with preoperatively expected perforation, in 72.0% with the diagnosis of acute inflammation, and in 84.0% when a chronic disease was anticipated preoperatively.	9880861
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Patients with histologically acute inflammation fulfilled more clinical criteria of appendicitis than those without (5.1 vs. 3.7).	9880863
Inflammation	Altered Intercellular Communication	The definite histological-pathological finding of acute inflammation postoperatively confirms the diagnosis.	9880864
Inflammation	Altered Intercellular Communication	Other findings especially chronic or chronic-recurrent inflammation should rise doubt.	9880864
Inflammation, Hematoma, Paracolic abscess, Small bowel obstruction, Pain, Postoperative	Altered Intercellular Communication	The Postoperative complication rate was very small: only 2.7% (relaparotomy because of small bowel obstruction: 4, paracolic abscess after severe phlegmonic inflammation: 4, infected haematomas: 2, relaparotomy because of unobserved deverticula of Meckel with severe inflammation: 1, delayed woundhealing: 8, postoperative pain with duration long than: 24 hours: 7).	9880883
Inflammation, Tympanic Membrane Perforation, Middle Ear Cholesteatoma	Altered Intercellular Communication	This condition, we called mallear epidermosis, is characterized by: i) a perforation of the tympanic membrane lining the handle of the malleus and the umbo; ii) a proliferation of keratin surrounding the handle of the malleus and diffusing into the mesotympanum on the internal side of the tympanic membrane, without matrix; and iii) a mild inflammation of the middle ear epithelium.	9881174
Adenocarcinoma of prostate, Inflammation, Pain Distress Question	Altered Intercellular Communication	We present the case of patient diagnosed of prostatic adenocarcinoma who was admitted because of pain and inflammation in the left side of the neck.	9882859
Inflammation	Altered Intercellular Communication	Data were less collected for women, patients operated by celioscopy and when histopathologic review concluded to absence of acute inflammation.	9882879
Inflammation, Gastritis, Ulcer, Intestinal metaplasia, Atrophic	Altered Intercellular Communication	The occurrence of antral inflammation, atrophy and intestinal metaplasia did not differ between those with HP- and HP+ ulcers, but activity of gastritis was more common in HP+ than in HP- patients (94.9% vs 47.1%, P=0.0001).	9883997
Inflammation, Bile Reflux, Ulcer, Intestinal metaplasia, Peptic Ulcer	Altered Intercellular Communication	In the logistic regression analysis, HP- peptic ulcer disease was independently associated with older age, bile reflux, the use of non-steroidal anti-inflammatory analgesics and intestinal metaplasia, while HP+ ulcer disease was associated with active inflammation of the antral mucosa and tendency to ulcer recurrence.	9883997
Inflammation, Dryness (characteristic), Inflammatory abnormality of the eye	Altered Intercellular Communication	Our results demonstrate that: (i) the ocular surface cytology and the analysis of tear film changes provide significant information in those patients where no other clinical signs are evident; (ii) DES symptoms are more frequent in women than in men (ratio about 2:1), both with ages over 51 years; (iii) DES is significantly associated with ocular surface inflammation, as detected by cytological methods, and (iv) ocular surface subclinical inflammation and ocular dryness are related to high concentrations of atmospheric polluters, in both sexes.	9885386
Inflammation, Granuloma, Folliculitis, Sebaceous Adenocarcinoma, melanoma, Hemangioma, Cavernous, Sweat Gland Neoplasms, Hidrocystoma	Altered Intercellular Communication	The values for melanoma were 50.0% and 28.6%, for sebaceous gland carcinoma 0.0% and 100.0%, and for uncommon lesions (nonspecific inflammation, actinic keratosis, granuloma, cavernous hemangioma, folliculitis, benign sweat gland tumour, eccrine hidrocystoma and collagenous tissue) 27.8% and 57.1%.	9885753
Communicable Diseases, Inflammation	Altered Intercellular Communication	When test samples are controlled for extraneous clinical origin of inflammation or infection, the combination of the IL-8 and f/t PSA assay results may offer an improved approach for distinguishing BPH from CaP.	9886603
Hemorrhage, Vitreous opacities, Uveitis	Altered Intercellular Communication	Both patients developed massive vitreous opacities due to uveal inflammation or hemorrhages that rendered the fundus difficult to visualize.	9886741
Inflammation, Scleritis, Glaucoma, CTCAE	Altered Intercellular Communication	A 60-year-old female patient presented with recurrent anterior, necrotizing scleritis with inflammation and a newly developed secondary glaucoma in the right eye.	9888136
Inflammation, Scleritis, Glaucoma, CTCAE, Uveitis	Altered Intercellular Communication	In our experience, diode laser cyclophotocoagulation is effective and safe in treating secondary glaucoma associated with anterior, necrotizing scleritis with inflammation and uveitis using reduced parameters for application.	9888136
Inflammation, Pancreatitis	Altered Intercellular Communication	Activated endogenous mediators of inflammation have important roles in the pathogenesis and complications of acute pancreatitis (AP).	9888656
Inflammation, Myxoid degeneration	Altered Intercellular Communication	The condition was not characterized by inflammation, but by thickening of the tendon sheath and most notably by the accumulation of mucopolysaccharide, an indicator of myxoid degeneration.	9888670
Experimental Organism Luteinized Unruptured Follicle, Dental Plaque, atherosclerotic	Altered Intercellular Communication	Inflammation of the atherosclerotic cap and shoulder of the plaque is a common and locally observed feature in unruptured plaques of femoral and coronary arteries.	9888866
Inflammation, Dental Plaque	Altered Intercellular Communication	Local inflammation is therefore considered a potential marker for plaque vulnerability.	9888866
Inflammation, Rupture	Altered Intercellular Communication	However, high specificity of inflammation for plaque rupture is a requisite for application of inflammation markers to detect rupture-prone lesions.	9888866
Dental Plaque, atherosclerotic	Altered Intercellular Communication	Inflammation of the cap and shoulder of the plaque is a common feature, locally observed, in atherosclerotic femoral and coronary arteries.	9888866
Inflammation, Abdominal Pain	Altered Intercellular Communication	These results suggest that it is possible to predict the severity of the disease to some extent as represented by objective markers of inflammation by finding the time from onset of abdominal pain to detection of bloody stool.	9889542
Chronic granulomatous, Periodontitis, Tooth structure, Inflammation	Altered Intercellular Communication	The trial of apex-locator application for improvement of endodontic management of root canals of a tooth as well as of ultratonotherapy in 120 patients aged 20-40 years with chronic granulomatous and granulating periodontitis has proved that ultratonotherapy relieves inflammation and stimulates regeneration of bone tissue.	9889717
Acute inflammation	Altered Intercellular Communication	Six eyes with pronounced postoperative inflammation responded well to antiinflammatory treatment.	9891894
Inflammation, Coronary heart disease, Cardiovascular Diseases	Altered Intercellular Communication	C-Reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992.	9892589
Inflammation, Complication Aspects	Altered Intercellular Communication	Inflammatory reactions in coronary plaques play an important role in the pathogenesis of acute atherothrombotic events; inflammation elsewhere is also associated with both atherogenesis generally and its thrombotic complications.	9892589
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	These results confirm the prognostic relevance of CRP, a sensitive systemic marker of inflammation, to the risk of CHD in a large, randomly selected cohort of initially healthy middle-aged men.	9892589
Inflammation, Atherosclerosis	Altered Intercellular Communication	They suggest that low-grade inflammation is involved in pathogenesis of atherosclerosis, especially its thrombo-occlusive complications.	9892589
Inflammation, Ischemia, Vertigo, Compression, Facial paralysis	Altered Intercellular Communication	Inflammation, compression or ischemia in the stenosed IAC may have resulted in the vertigo and facial palsy.	9892864
Intestinal metaplasia, Inflammation, Helicobacter pylori, Atrophic	Altered Intercellular Communication	Biopsies of body and antral mucosa for other parameters were similar between treatments for Helicobacter pylori colonization, presence or degree of inflammation, atrophy or intestinal metaplasia at the end-point.	9892879
ARCN1 gene, Inflammation, Hypoxemia	Altered Intercellular Communication	We conclude that increased plasma sFas, which is independent of hypoxaemia, and increases in PaCO2, TNF-alpha, IL-6 and inflammation, may be associated with progression of COPD.	9893764
Gingivitis, Superficial ulcer	Altered Intercellular Communication	A 38-year-old man presented with gingival inflammation together with erosions of the penis.	9894362
Inflammation, Necrosis	Altered Intercellular Communication	In the nearest postoperative period partial incompetence of the coloanal anastomosis, necrosis of the reservoir wall and its inflammation appeared in 4 patients.	9915065
Inflammation, Hyperparathyroidism	Altered Intercellular Communication	EPO resistance is usually attributed to iron or vitamin deficiency, hyperparathyroidism, aluminum toxicity, or inflammation.	9915269
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	We sought to elucidate the role of osteopontin in granulomatous inflammation by characterizing its expression in different stages of sarcoidosis and its effector function on T cells in vitro.	9916729
Granulomatous inflammation	Altered Intercellular Communication	These results suggest a novel mechanism by which osteopontin and thrombin modulate T cell recruitment and activation in granulomatous inflammation.	9916729
Inflammation, Spondylitis	Altered Intercellular Communication	Ankylosing spondylitis (AS) is reportedly associated with subclinical endoscopic gut inflammation in up to 57% of patients.	9918253
Inflammation, Intraoperative Complications, Obesity	Altered Intercellular Communication	The main reasons for conversion to open surgery were inflammation, obesity, anesthetic problems, technical difficulties, intraoperative complications, and intraoperative decisions concerning oncological resection.	9918619
Asthma, Eosinophilic inflammation	Altered Intercellular Communication	The serum-eosinophil cationic protein level (S-ECP) has been promoted as a biomarker of asthma that reflects the degree of bronchial eosinophilic inflammation.	9920218
Inflammation, Asthma	Altered Intercellular Communication	Although S-ECP and eosinophils are not diagnostic of asthma they are useful inflammation markers especially in the context of clinical studies.	9920218
Inflammation, Foreign Bodies, Communicable Diseases, Abscess, Sinusitis, Osteomyelitis	Altered Intercellular Communication	Contiguous inflammation of the skin (CIS) is a condition comprising localized inflammatory skin reactions which are secondary to a source of infection originating in deeper anatomical structures (bacterial or sterile abscesses, neoplasm-associated inflammations, foreign bodies, osteomyelitis, sinusitis, etc.).	9920989
Inflammation, Erythema	Altered Intercellular Communication	The main clinical symptom of contiguous inflammation of the skin is an asymmetrical, localized and painful erythema in combination with different case-specific symptoms.	9920989
Inflammation, Foreign Bodies, Communicable Diseases, Abscess, Sinusitis, Osteomyelitis	Altered Intercellular Communication	Contiguous inflammation of the skin (CIS) is a condition comprising localized inflammatory skin reactions which are secondary to a source of infection originating in deeper anatomical structures (bacterial or sterile abscesses, neoplasm-associated inflammations, foreign bodies, osteomyelitis, sinusitis, etc.).	9920989
Inflammation, Critical Illness	Altered Intercellular Communication	The study findings suggest that heparin in this dose regimen may be unlikely to influence endothelial inflammation or endothelial function in critically ill patients.	9921711
Tubulitis Assessment, Interstitial inflammation	Altered Intercellular Communication	Histopathologic examination of the allografts showed interstitial inflammation with tubulitis in 7 of 10 (70%) patients; in 3 of 10 (30%) patients, viral inclusions were present in the glomerular capillary endothelia without any associated inflammatory response.	9921804
Chronic heart failure	Altered Intercellular Communication	Comparison of VO2 kinetics with peak VO2, neurohormones, and clinical signs of chronic heart failure.	9922345
Ischemia, Inflammation, Facial Pain	Altered Intercellular Communication	Intraosseous ischemia and chronic inflammation were suggested as a pathoetiologic mechanism for at least some patients with atypical facial pain.	9922427
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Our data suggest that rapidly destructive hip osteoarthritis may be associated with some degree of inflammation reflected by a small but significant increase in serum C-reactive protein levels.	9923044
Inflammation	Altered Intercellular Communication	Histologic study of a stereotactic biopsy specimen demonstrated inflammation characterized by perivascular mononuclear cell infiltration.	9923770
Ischemia	Altered Intercellular Communication	The formation of reactive oxygen species (ROS), although a normal cellular activity, is considerably enhanced under chronic inflammatory conditions and ischemia.	9924806
Inflammation	Altered Intercellular Communication	Furthermore, the histologic evaluation in four cups from groups B and C revealed normal bone formation without inflammation or fibrotic tissue around the cups, promising long-term survival.	9925196
Cholecystitis, Biliary calculi	Altered Intercellular Communication	The variables of the protocol were: gallbladder stones, BS and acute and chronic gallbladder inflammation.	9926205
Cholecystitis, Lithiasis	Altered Intercellular Communication	Considering the mentioned criteria, we entered to the study 2682 patients, 17.8% (n = 479) had lithiasis, 13.2% (n = 356) had BS, 2% (n = 54) had acute gallbladder inflammation and 2.3% (n = 64) had chronic gallbladder inflammation.	9926205
Inflammation, Infection caused by Helicobacter pylori, Malignant neoplasm of stomach	Altered Intercellular Communication	Chronic inflammation induced by Helicobacter pylori infection has been associated with an increased risk of stomach cancer.	9926291
Pneumonitis	Altered Intercellular Communication	The observed lag structure is consistent with particulate-induced pulmonary inflammation and cytokine release, but the biological relevance requires further study.	9927345
Mumps, Swelling, Inflammation	Altered Intercellular Communication	The parotid infection also extended by continuity into the lateral pharyngeal space and contiguous deep neck spaces, causing airway-threatening, extensive inflammation and swelling of the epiglottis and parapharyngeal soft tissues.	9928699
Bacterial Infections	Altered Intercellular Communication	Procalcitonin (PCT) blood levels may distinguish between bacterial infections and a non-bacterial systemic inflammation.	9928856
Inflammation, Bacterial Infections	Altered Intercellular Communication	We investigated the influence of ECC, ECC modified by application of aprotinin, systemic inflammation, and bacterial infection on the PCT values.	9928856
Fibrosis Assessment, Portal inflammation, Necrosis	Altered Intercellular Communication	The serum alanine aminotransferase level was correlated with hepatocyte necrosis (piecemeal and lobular) but not with portal inflammation or fibrosis.	9930149
Inflammation, Perforation (observation), Neoplasms, Specimen Source Codes - Abscess, Specimen Type - Fistula	Altered Intercellular Communication	Histological findings verified an inflammatory tumor, and abscess, a fistula or perforation in 50% and circumscript inflammation in 37%.	9931606
Inflammation, Postoperative Complications	Altered Intercellular Communication	Patients with glutamine substitution showed decreased systemic inflammation, significant faster compensation for postoperative immunosuppression and a lower incidence of postoperative complications.	9931687
Pleural Effusion, CTCAE, Pleurisy, Cardiomyopathies, Hypothyroidism	Altered Intercellular Communication	In a 50-year-old woman with PM, combined process of pleural inflammation, cardiomyopathy and coexisting hypothyroidism were considered to be responsible for the accumulation of the massive pleural effusion.	9932642
Pleural Effusion, CTCAE, Pleurisy, Demographics Domain, Pneumonia, Interstitial	Altered Intercellular Communication	However, in a 34-year-old man with DM, pleural inflammation associated with interstitial pneumonia or pleural microvasculopathy in DM was considered to be responsible for the accumulation of the massive pleural effusion.	9932642
Metaplasia, Hiatal Hernia, Esophagitis	Altered Intercellular Communication	Metaplasia was not related to reflux symptoms, hiatus hernia, or endoscopic esophageal inflammation.	9934738
Inflammation, Asthma, Airway Obstruction	Altered Intercellular Communication	The purpose of this study was to demonstrate, by using factor analysis, that reversible airway obstruction, BHR, and eosinophilic inflammation of the bronchial tree, as assessed by cytologic and biochemical analysis of sputum, may be considered separate dimensions that characterize chronic bronchial asthma.	9949313
Airway structure, asthma chronic	Altered Intercellular Communication	We conclude that airway function, baseline BHR, and airway inflammation may be considered separate dimensions in the description of chronic asthma.	9949313
Inflammation, F11R gene	Altered Intercellular Communication	In JCA patients dolgit relieved symptoms of local inflammation.	9949465
Sjogrens Syndrome	Altered Intercellular Communication	Sjogren's syndrome is a chronic inflammatory condition of unknown aetiology and autoimmune pathology.	9951023
Inflammation	Altered Intercellular Communication	[Combined treatment of postoperative inflammations after intraocular lenses implantation].	9951389
Communicable Diseases, Hypotension, Orthostatic	Altered Intercellular Communication	Hormonal, cardiological and infectious causes of the orthostatic hypotension were excluded.	9951452
Inflammation, Aphthous Stomatitis	Altered Intercellular Communication	These findings did not have a statistically significant correlation with the presence or absence of aqueous inflammation or oral aphthous ulcerations.	9951480
Inflammation, Retinal Diseases, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation after phacoemulsification in patients with type 2 diabetes mellitus without retinopathy: prospective study.	9951669
Cataract, Inflammation, Retinal Diseases, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	To evaluate inflammation after clear corneal incision (CCI) cataract surgery in patients with noninsulin-dependent diabetes mellitus and no retinopathy.	9951669
Cholangiocarcinoma, Inflammation, Papillomatosis, Adenocarcinoma of ampulla of Vater, Adenoma of ampulla of Vater	Altered Intercellular Communication	A histological diagnosis was obtained in 24 cases of the 27 patients (sensitivity 89%) and included cholangiocarcinoma (n=8), papillomatosis (n=3), ampullary adenoma (n=1), ampullary adenocarcinoma (n=1), hepatoma with intrabile duct invasion (n=1), and chronic inflammation (n=10).	9951868
Cholecystitis	Altered Intercellular Communication	Data were correlated with in vivo contractility, bile composition, and gallbladder wall inflammation.	9952243
Inflammation, Candida (fungus)	Altered Intercellular Communication	The increase in the epithelial width and inflammation degree is probably associated with the colonization of the denture bases with Candida organisms.	9972170
Hyperthyroidism	Altered Intercellular Communication	Hormonal evaluation resulted in hyperthyroidism with high serum TSH concentrations.	9972679
Dermatomyositis, Myositis	Altered Intercellular Communication	Thus, one-third of patients with dermatomyositis and clinically normal muscles may have detectable muscle inflammation on MR images, indicating that MR has a potential role for locating the relevant biopsy site and for longitudinal follow up.	9973906
Inflammation	Altered Intercellular Communication	The false-positive result of the Meckel scan may be the result of inflammation from the periumbilical laparoscopic port site.	9988066
Inflammation, Lung Diseases, Interstitial	Altered Intercellular Communication	Interstitial lung disease (ILD) is characterized by inflammation within the alveolar walls and interstitium of the lungs.	9988067
Inflammation, Critical Illness	Altered Intercellular Communication	Critically ill patients: immunological evidence of inflammation in muscle biopsy.	9988135
Critical Illness, myonecrosis, MARCKS wt Allele	Altered Intercellular Communication	To verify whether muscle necrosis in critically ill patients could be due to an inflammatory process, we tested muscle biopsies from five intensive care patients with different inflammation-specific immunocytochemical markers (antibodies anti-class I major histocompatibility complex products (class I MHCP or HLA I), membrane attack complex (MAC), T lymphocytes helper-inducer (CD4), cytotoxic (CD8) and pan-B-lymphocytes).	9988135
Inflammation, Muscle damage, Critical Illness	Altered Intercellular Communication	Our results suggest that inflammation may be a component of muscle damage in some critically ill patients.	9988135
Inflammation	Altered Intercellular Communication	The informativity of the laboratory investigations indexes for the postoperative course prognosis and early peritoneal cavity inflammation was revealed.	9989032
Osteomyelitis, Arthritis, Acute inflammation	Altered Intercellular Communication	Subchondral acute inflammation in severe arthritis: a sterile osteomyelitis?	9989846
Degenerative polyarthritis, Inflammation, Arthritis	Altered Intercellular Communication	Although arthritis is often associated with synovial inflammation, the osseous changes in inflammatory and degenerative arthritis are principally reactive, and typically lack an acute inflammatory component.	9989846
Osteomyelitis, Tuberculosis, Osteoarticular, Inflammation	Altered Intercellular Communication	We have recently encountered several osteoarticular specimens removed at the time of large joint arthroplasty that have shown a distinctive pattern of subchondral acute inflammation (SCAI) resembling acute bacterial osteomyelitis.	9989846
Subchondral Cysts, Inflammation	Altered Intercellular Communication	In all cases, the inflammation was subchondral (within 1.0 cm of the joint surface), and it was frequently associated with subchondral cysts.	9989846
Inflammation, Bone necrosis	Altered Intercellular Communication	In osteonecrotic foci, the suppurative inflammation was diffuse within the marrow space, whereas in viable bone it was nodular and vaguely granulomatous.	9989846
Inflammation, Bacterial Infections	Altered Intercellular Communication	Although we cannot definitively exclude bacterial infection as a cause of SCAI, the histologic and clinical features suggest that SCAI likely represents a noninfectious sterile form of inflammation.	9989846
Degenerative polyarthritis, Rheumatoid Arthritis, Acute inflammation	Altered Intercellular Communication	Subchondral acute inflammation is possibly secondary to synovial fluid insudation into subchondral cancellous bone in the setting of severe osteoarthritis and/or rheumatoid arthritis.	9989846
Hemorrhagic, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	As for the seminal vesicle, the patients whose seminal vesicle was seen in higher intensity than the prostate gland in T1 weighted images were diagnosed as having hemorrhagic focus and the patients whose seminal vesicle was seen in low intensity both in T1 and T2 weighted images were diagnosed as having fibrosis caused by chronic inflammation.	9990227
Inflammation, Hemorrhage, Cyst of seminal vesicle	Altered Intercellular Communication	Abnormality in the seminal vesicle was indicated in 30 cases (43%) including hemorrhage of seminal vesicle in 25 cases, chronic inflammation in five cases and cyst of seminal vesicle in one case.	9990227
Papillary thyroid carcinoma, Adenolymphoma, Inflammation, Neoplasms	Altered Intercellular Communication	Warthinklike tumor of thyroid is a recently described variant of papillary thyroid carcinoma characterized histologically by a papillary architecture, oxyphilic tumor cells and extensive, chronic inflammation.	9990276
Inflammation	Altered Intercellular Communication	Chronic inflammation was abundant and intimately associated with neoplastic cell groups.	9990276
Communicable Diseases, Inflammation	Altered Intercellular Communication	Neutrophils are unable to bind to ligands on the endothelium, and so cannot leave the circulation during inflammation or infection.	9990374
Blindness, Inflammation, Uveitis	Altered Intercellular Communication	Uveitis is a general term that refers to the inflammation of uveal tract, which is an important cause of blindness in young people.	10021782
Vision Disorders	Altered Intercellular Communication	The visual disorder may be related to an imbalance of certain neurotransmitters in the visual system of patients, e.g.	10023112
Inflammation, Helicobacter pylori	Altered Intercellular Communication	The significance of cagA and vacA subtypes of Helicobacter pylori in the pathogenesis of inflammation and peptic ulceration.	10023339
Inflammation, Helicobacter pylori	Altered Intercellular Communication	To assess the significance of cagA and vacA subtypes of Helicobacter pylori in relation to inflammation and density of bacterial colonisation in vivo within a dyspeptic UK population.	10023339
Inflammation	Altered Intercellular Communication	There was a significant association between cagA positive strains and increased inflammation and bacterial density.	10023339
Inflammation	Altered Intercellular Communication	The vacA s1 type independently correlated with extensive chronic inflammation but there was no association with bacterial density.	10023339
Inflammation	Altered Intercellular Communication	The results suggest that cagA is important in the pathogenesis of inflammation and peptic ulceration.	10023339
Granuloma, Inflammation	Altered Intercellular Communication	Biopsy of the mass from the paranasal sinus was carried out and the histological diagnosis was a granulomatous lesion with non-specific inflammation.	10024985
Chronic thyroiditis, AVP gene, Hypopituitarism	Altered Intercellular Communication	Hormonal examination indicated hypopituitarism with masked diabetes insipidus and chronic thyroiditis.	10024988
Refractory anemias, destruction joint, Arthritis	Altered Intercellular Communication	Proteolytic enzymes involved in the cascade of joint destruction are potentially useful parameters to monitor the extent of joint inflammation in RA.	10025098
Seizures, Epilepsy, Temporal Lobe	Altered Intercellular Communication	These data support the hypothesis that excitatory and inhibitory neurotransmission and seizure susceptibility could be altered by neuronal and glial transporters in TLE patients.	10025773
Cortical Dysplasia, Inflammation, Epilepsy	Altered Intercellular Communication	Cortical dysplasia with angiodysgenesis and chronic inflammation in multifocal partial epilepsy.	10025810
Angiodysplasia, Cortical Dysplasia, Inflammation, Avascular necrosis of bone	Altered Intercellular Communication	The resected temporal lobe revealed cortical dysplasia and angiodysplasia with foci of more recent ischemic necrosis and chronic inflammation as an explanation for the clinical deterioration.	10025810
Inflammation, Esophagitis	Altered Intercellular Communication	The innervation of the oesophageal mucosa is not altered in non-inflamed tissue of patients with oesophagitis but alters in response to inflammation, where there is a selective increase (about three- to fourfold) in VIP containing nerves.	10026314
Inflammation, VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)	Altered Intercellular Communication	The extensive cutaneous inflammation prior to the onset of vitiligo in our patient with VKH disease has not been reported before and strongly suggests an immunologic etiology for VKH disease.	10026405
Inflammation, Alopecia Areata	Altered Intercellular Communication	The additional presence of peribulbar lymphocytic inflammation could indicate that the patient had a variant of alopecia areata.	10027527
Alopecia Areata, Alopecia, CTCAE, Inflammation	Altered Intercellular Communication	The clinical presentation of a slowly progressive diffuse alopecia without progression to clinically recognizable alopecia areata and the prominent lymphocytic inflammation involving the stem cell compartment may prompt a reexamination of similar cases currently classified as chronic diffuse alopecia areata.	10027527
Inflammation, Crohn Disease	Altered Intercellular Communication	Alterations in the structure and/or quantity of mucins could alter the barrier function of mucus and play a role in initiating and maintaining mucosal inflammation in Crohn's disease.	10028446
Inflammation, Sarcoidosis	Altered Intercellular Communication	Sarcoidosis involves the nervous system about 5% of the time and usually manifests as a granulomatous inflammation of the basal meninges and hypothalamus.	10029426
Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	Systemic inflammatory response syndrome without systemic inflammation in acutely ill patients admitted to hospital in a medical emergency.	10029565
Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	Criteria of the systemic inflammatory response syndrome (SIRS) are known to include patients without systemic inflammation.	10029565
Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	Our aim was to explore additional markers of inflammation that would distinguish SIRS patients with systemic inflammation from patients without inflammation.	10029565
Sepsis, Inflammation	Altered Intercellular Communication	The systemic inflammation composite score of SIRS2 patients (median 1.5; range 0-8, n=56) was lower than that of SIRS3 patients (3.5; range 0-9, n=14, P=0.013) and that of sepsis patients (5.0; range 3-10, n=19, P<0.001).	10029565
Inflammation	Altered Intercellular Communication	The systemic inflammation composite score was 0 in 13/94 patients.	10029565
Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	Quantifying phagocyte CD11b expression and serum interleukin-6 and C-reactive protein concurrently provides a means to discriminate SIRS patients with systemic inflammation from patients without systemic inflammation.	10029565
Inflammation	Altered Intercellular Communication	Histopathology showed focal acute inflammation surrounding collections of acid-fast bacilli, which were speciated as M. abscessus.	10030567
Exophthalmos, Disorder of the optic nerve, Orbital Pseudotumor, External Ophthalmoplegia	Altered Intercellular Communication	Four days later, severe orbital inflammation resulted in a visual acuity of counting fingers, proptosis, optic neuropathy, and total external ophthalmoplegia in the eye.	10030580
Inflammatory abnormality of the eye	Altered Intercellular Communication	During a 2-month period, the patient recovered to a visual acuity of 20/70, near normal motility, and normal intraocular pressure, and the ocular and orbital inflammation resolved.	10030580
Inflammation, Brown Tendon Sheath Syndrome	Altered Intercellular Communication	The inflammation of the trochlea/tendon complex that can cause acquired Brown syndrome can be demonstrated on magnetic resonance image.	10030581
Airway structure, Nasal Polyps	Altered Intercellular Communication	Airway inflammation in patients with nasal polyps is characterized by the increased presence of eosinophils, the numbers of which are reduced after treatment with topical corticosteroids.	10030836
Cataract, Inflammation	Altered Intercellular Communication	A mature cataract was removed subsequently, and the eye has remained free of inflammation postoperatively.	10037211
Inflammation, Hemorrhage	Altered Intercellular Communication	Simple nephrectomy is technically demanding in patients with recurrent inflammation or bleeding.	10037359
Inflammation, Abnormally opaque structure (morphologic abnormality), Hypopyon	Altered Intercellular Communication	The slit-lamp examination revealed severe inflammation of the anterior chamber with hypopyon, posterior synechiae, and opacity of the posterior lens capsule.	10048013
Chronic Lymphocytic Leukemia, Hypercalcemia, CTCAE	Altered Intercellular Communication	Parathyroid hormone-related protein (PTH-rP)-associated hypercalcemia in a patient with an atypical chronic lymphocytic leukemia.	10048292
Chronic Lymphocytic Leukemia, Hypercalcemia, CTCAE	Altered Intercellular Communication	We describe a patient with an atypical chronic lymphocytic leukemia (CLL) of the mixed cell type with a hypercalcemia due to parathyroid hormone-related protein production by the malignant B cells.	10048292
Inflammation, Carpometacarpal joint structure	Altered Intercellular Communication	Overall, splinting was found to be a well-tolerated and effective conservative treatment to diminish, but not completely eliminate, the symptoms of carpometacarpal joint arthritis and inflammation.	10048521
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Several studies have suggested that clinical indices of disease activity in inflammatory bowel disease (IBD) do not adequately reflect the degree of inflammation in most such patients.	10048733
Nephritis	Altered Intercellular Communication	However, only increased circulating VCAM-1 serum levels correlated significantly with the histological state of renal inflammation and could be used as a disease marker.	10050078
Inflammation	Altered Intercellular Communication	The increased risk factors--gender, age of the patient, the cholelithic disease existence duration, the acuteness of inflammation, the operations performed earlier on the abdominal cavity organs, influencing the laparoscopic cholecystectomy conduction for Courvoisier's gallbladder--were analyzed.	10050373
Inflammation	Altered Intercellular Communication	Basing on the examination results of 68 patients with complicated cholelithic disease the diagnosis value of the bile biochemical contents changes was established for the inflammation course prognosis.	10050374
Communicable Diseases, Inflammation	Altered Intercellular Communication	Hepatocytic dystrophy in the absence of inflammation was more common in prolonged opisthorchiasis with low infection rates.	10050550
Granulomatous inflammation, Necrosis, Coccidioides immitis	Altered Intercellular Communication	Microscopic examination revealed extensive necrosis of lung parenchyma, suppurative granulomatous inflammation with Coccidioides immitis organisms and rare acid-fast bacilli.	10050795
Inflammation, Edema	Altered Intercellular Communication	Compared with control lambs, chronically ventilated preterm lambs had pulmonary histopathology characterized by nonuniform inflation patterns, impaired alveolar formation, abnormal abundance of elastin, increased muscularization of terminal bronchioles, and inflammation and edema.	10051278
Graves Disease, Myositis	Altered Intercellular Communication	A 63 kDa skeletal muscle protein associated with eye muscle inflammation in Graves' disease is identified as the calcium binding protein calsequestrin.	10052680
Premalignant Lesion, Chronic inflammation, Leukoplakia	Altered Intercellular Communication	By immunohistochemistry, we examined the expression pattern of integrins alpha2beta1, alpha3beta1, alpha6beta4 and laminin-5 in biopsies from SCCs (n=18), premalignant lesions (leukoplakias, n=21) and non-premalignant tissue with chronic inflammation (n=11).	10052726
Loss of Merlin Expression, Hepatic inflammation	Altered Intercellular Communication	Loss of hepatic expression did not appear to be immune mediated because there was no evidence of hepatic inflammation or appearance of antiadenoviral neutralizing antibodies.	10052795
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	Agreement in recognizing the presence of H. pylori colonization of the gastric mucosa, activity of inflammation and intestinal metaplasia was over 90%.	10064391
Inflammation, Atrophic	Altered Intercellular Communication	Agreement in recognizing chronic inflammation in the body and atrophy in the antrum was between 78 and 89% respectively.	10064391
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	The kappa values were excellent (more than 0.75) for the grade of H. pylori in the body, good (between 0.50 and 0.75) for the grade of H. pylori in the antrum, grade of inflammatory activity and intestinal metaplasia in the antrum and moderate to good (0.38-0.53) for the grade of chronic inflammation.	10064391
Atrophic, Chronic inflammation	Altered Intercellular Communication	More strict criteria should be used for atrophy and to differentiate normal and mild chronic inflammation.	10064391
Refractory anemias, Degenerative polyarthritis, Rheumatoid Arthritis, Degenerative disorder, Hemophilic arthropathy	Altered Intercellular Communication	To investigate the pathogenetic mechanisms of haemophilic arthropathy (HA) by comparing end-stage arthropathy with osteoarthritis (OA; a degenerative joint disorder) and rheumatoid arthritis (RA; an inflammation-mediated joint disease).	10064394
Inflammation, Hematoxylin and eosin stain method, Refractory anemias, Degenerative polyarthritis, Tumor necrosis	Altered Intercellular Communication	Cartilage in HA exhibited characteristics of degenerative joint disease (OA), as evidenced by morphological, histochemical (Safranin-O fast green-iron haematoxylin, Mankin grade) and biochemical (proteoglycan synthesis, glycosaminoglycan content and DNA content) changes, whereas synovium in HA showed characteristics of inflammation-mediated joint disease (RA), as evidenced by histochemical (inflammation, haematoxylin and eosin (H&E) and iron deposition, Perls' blue) and biochemical changes (interleukin (IL)-1, IL-6, tumour necrosis factor (TNF)alpha and catabolic properties).	10064394
Inflammation	Altered Intercellular Communication	On the basis of these results and published information, it appears that degenerative cartilage changes have a dominant role in HA and are augmented by relatively mild inflammation of the synovium.	10064394
Inflammation, Granuloma	Altered Intercellular Communication	Histopathology of the specimen showed chronic inflammation with granuloma formation and T lymphycyte infiltrate around the small vessels, though fungus was not detected in the tissue.	10065464
Airway structure	Altered Intercellular Communication	These results suggest that a significant proportion of children with mild-intermittent asthma may have airway inflammation, as shown by the presence of elevated levels of nitric oxide in the exhaled air.	10065675
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor-alpha (TNF) is a mediator of inflammation and cellular immune response.	10068094
YME1L1 gene, Heart failure	Altered Intercellular Communication	Judging from the difference in not only the biological actions but also the hormonal profiles between AM and PAMP, they may differentially modulate the cardiovascular system in patients with heart failure, although they are processed from the same precursor.	10068849
Inflammation, Fibrosis Assessment, Squamous metaplasia	Altered Intercellular Communication	Histologic analysis indicated a fragment of thyroid tissue with chronic inflammation, fibrosis, and squamous metaplasia.	10069729
Hepatocellular, Hepatic inflammation	Altered Intercellular Communication	Conversely, the extent of hepatic inflammation and hepatocellular destruction was not statistically different between the two groups.	10071027
Bacteriuria, Cystitis, Pyuria	Altered Intercellular Communication	Elderly women with pyuria but without bacteriuria should be studied for other causes of urinary tract inflammation.	10071422
negative regulation of urine volume, Chronic Kidney Diseases	Altered Intercellular Communication	The results show that plasma ANP level is decreased after volume reduction in patients with chronic renal failure, whereas other hormonal systems are unresponsive.	10072093
Inflammation, Acute Coronary Syndrome, Angina, Unstable	Altered Intercellular Communication	It has been suggested that active inflammation plays an important role in the pathogenesis of acute coronary syndromes, including unstable angina.	10073782
Inflammation, Coronary Arteriosclerosis, Atherosclerosis	Altered Intercellular Communication	Systemic serum markers of inflammation are elevated in diseases due to atherosclerosis, but have not been associated with the extent of atherosclerotic disease.	10073853
Inflammation, Sore to touch	Altered Intercellular Communication	Initial examination revealed no light-perception, tenderness and marked inflammation of the left eye.	10074740
Inflammation	Altered Intercellular Communication	There was severe inflammation both in the anterior chamber and vitreous cavity.	10074740
Necrotizing granulomatous inflammation, acute necrotizing	Altered Intercellular Communication	Histopathological examination of the primary and recurrent lesions revealed partly degenerated hyphae associated with acute necrotizing and chronic granulomatous inflammation.	10074968
Inflammation	Altered Intercellular Communication	These results suggest that the increased shift towards a Th1 response is mainly restricted to the actual site of inflammation and that circulating T cells do not show a similar response, presumably because activated cells in peripheral blood are too few.	10075025
Inflammation	Altered Intercellular Communication	Further research on cytokine profiles measuring T-cell activation in CoD should be focused on the actual tissue of inflammation.	10075025
Respiratory Distress Syndrome, Adult, Acute inflammation, Edema	Altered Intercellular Communication	Levels of procollagen peptide III, a marker of collagen synthesis, were increased in permeability edema fluids compared with hydrostatic edema fluids or plasma, confirming that alveolar collagen synthesis begins very early and in parallel with acute inflammation in ARDS.	10075054
Inflammation	Altered Intercellular Communication	The inflammation is mostly limited to the lung, with low levels of inflammatory mediators in the systemic circulation.	10075054
Myocarditis	Altered Intercellular Communication	Histological and immunohistological analyses were performed to detect myocardial inflammation.	10077520
Sepsis, Suppurative inflammation, Affection	Altered Intercellular Communication	While sepsis present in 73 patients with purulent-inflammatory affection of soft tissues and in 76 patients with local purulent inflammation the dynamics of processes of peroxidal oxidation of lipids (POL) and of antioxidant system (AOS) was studied up.	10077914
Inflammation, Hyphema	Altered Intercellular Communication	The P-DS group experienced significantly less inflammation (40.0% versus 83.0%; P = .0012) and hyphema (6.7% versus 36.7%; P = .010) than the P-T group.	10079438
Inflammation, Necrosis	Altered Intercellular Communication	Plasma TIMP-1 was significantly correlated with histological activity index (r = 0.45), portal inflammation (r = 0.48), periportal necrosis (r = 0.34) and focal necrosis (r = 0.38).	10080160
Alzheimers Disease	Altered Intercellular Communication	Glutamatergic neurotransmission is important for memory and cognition and is severely affected in Alzheimer's disease.	10080566
Inflammation	Altered Intercellular Communication	The pathogenetic mechanism responsible for glandular inflammation appears to be different from that in primary SS.	10081515
Inflammation, Candidiasis	Altered Intercellular Communication	Oral mucosa inflammation (as in oral candidiasis) may enhance its transmucosal absorption.	10084413
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Eosinophilic inflammation in the airway is related to glucocorticoid reversibility in patients with pulmonary emphysema.	10084478
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	These findings suggest that the eosinophilic inflammation, not neutrophilic inflammation, in the airway is involved in the reversible part of the airflow obstruction in response to glucocorticoids in patients with pulmonary emphysema.	10084478
Infarction, Lesion, Neoplasms	Altered Intercellular Communication	Brain MRI was done in 25 of the 44 patients and confirmed pontine lesions in six (two infarcts, three inflammations, one tumour).	10084533
Infarction, Inflammation, Appendix Epiploica	Altered Intercellular Communication	The CT scan confirmed the presence of this lesion which appeared to be an infarction of an epiploic appendix with subsequent inflammation, called primary epiploic appendagitis.	10086133
Inflammation	Altered Intercellular Communication	This disease may therefore serve to elucidate dysregulated modulation of adhesion molecule expression in conditions of chronic inflammation and impaired wound healing.	10086854
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	Ketorolac tromethamine 0.5% ophthalmic solution in the treatment of moderate to severe ocular inflammation after cataract surgery: a randomized, vehicle-controlled clinical trial.	10088733
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Taken together, these results suggest that the presence of virus-specific T cells within inflamed lesions of patients suffering from autoimmune diseases is a general phenomenon associated with chronic inflammation rather than the initiating cause of the autoimmune process.	10092102
Inflammation, Sarcoidosis	Altered Intercellular Communication	The granulomatous inflammation in sarcoidosis is driven by the interplay between T cells and macrophages.	10092696
Inflammation, Neoplasms, Mammary Neoplasms	Altered Intercellular Communication	In breast tumors, increases in the ER-beta2:ER-beta1 and ER-beta5:ER-beta1 mRNA expression ratios were observed, which positively correlated with the level of tumor inflammation and tumor grade, respectively.	10096542
Granulomatous inflammation	Altered Intercellular Communication	If granulomatous inflammation (GI) was also considered a positive result, sensitivity increased to 53%; false positive cases of GI reduced PPV to 80%, while specificity (98%) and NPV (95%) changed little.	10097702
Granulomatous inflammation	Altered Intercellular Communication	However, nondiagnostic results, such as granulomatous inflammation, should be interpreted with caution.	10097702
Inflammation, Hemorrhage, Malignant Neoplasms	Altered Intercellular Communication	Based on this experience with vitreous specimens submitted for clinical reasons, we found that they could be divided into three broad diagnostic categories: inflammation/infection (54 specimens/41 patients), hemorrhage (12 specimens/12 patients) and malignancy (8 specimens/7 patients).	10097710
Cataract, Inflammation	Altered Intercellular Communication	Absolute control of inflammation, atraumatic surgery, and regular postoperative follow-up can improve the results of cataract extraction.	10100252
Inflammation, Fibrosis Assessment, Neoplasms	Altered Intercellular Communication	Pathologic examination failed to reveal evidence of inflammation, fibrosis or neoplasia.	10100414
Hearing problem, Ear Inflammation	Altered Intercellular Communication	In the analysed group 55% of children suffered from recurrent upper respiratory tract inflammations, 12.5% from recurrent otitis, 12.5%--increased neck nodules, 12.5% from hearing disorders, and 42.5% of children breathed by mouth.	10101518
Azoospermia, Primary hypogonadism	Altered Intercellular Communication	Repeated seminal analyses showed azoospermia, and serum hormonal levels suggested a state of a hypergonadotropic hypogonadism.	10101575
Pain Distress Question, Inflammation	Altered Intercellular Communication	As all NSAIDs can reduce pain and inflammation, selection of a particular NSAID should be based on careful consideration of pharmacologic and clinical differences.	10150359
Abdominal Pain, Pelvic Inflammatory Disease	Altered Intercellular Communication	Women who have been sterilized, have not had previous abdominal surgery, or have evidence of old pelvic inflammation report more postoperative backache and deep abdominal pain but no greater skin or shoulder discomfort.	10150392
Eye pain, Infiltrate of cornea, Inflammatory abnormality of the eye	Altered Intercellular Communication	Two days after antibiotic therapy was initiated, the ocular inflammation and corneal infiltrates had regressed and ocular pain was relieved.	10188371
Dermatitis	Altered Intercellular Communication	Five patients (36%) experienced a substantial response with reduction of skin inflammation by at least 75%, whereas in one patient (7%) disease activity was reduced by more than 50%.	10188677
Herpes zoster disease, Palmar-plantar erythrodysesthesia syndrome	Altered Intercellular Communication	Chemotherapy-induced inflammation in seborrheic keratoses mimicking disseminated herpes zoster.	10188692
Coughing, Inflammation, Recurrent lower respiratory tract infection	Altered Intercellular Communication	We considered chronic cough as an indicator of chronic lung infection or inflammation in the original Framingham Heart Study participants aged 47 to 89 years.	10190375
Chronic cough, Electrocardiogram: myocardial infarction (finding), Infectious Lung Disorder, Inflammation	Altered Intercellular Communication	These findings provide evidence that chronic cough, a clinical manifestation of pulmonary infection or chronic inflammation, is associated with the risk of myocardial infarction.	10190375
Hepatocellular, Inflammation, Necrosis	Altered Intercellular Communication	The degree of severity of both lymphocytic hepatocellular piecemeal necrosis and lobular inflammation and necrosis was mainly associated with increased gammaglobulin and IgG levels and to a lesser extent with increased IgM and aspartate aminotransferase levels.	10190722
Inflammation, Necrosis, Fibrosis Assessment, Primary Biliary Cholangitis, Destruction (action), Cholangitis	Altered Intercellular Communication	We propose that the picture of primary biliary cirrhosis results from the clinical and biochemical expression of three distinct processes, e.g., bile duct inflammation and destruction, parenchymal inflammation and necrosis, and fibrosis.	10190722
Inflammation, Asthma, Respiratory Tract Infections	Altered Intercellular Communication	To more fully understand how viral respiratory tract infections influence asthma, investigators have evaluated the effect of respiratory tract infections on airway symptoms, function, and inflammation.	10191921
Airway structure	Altered Intercellular Communication	Although the mechanisms by which respiratory viruses enhance lower airway inflammation are not established, cytokines may play a key role in this process.	10191921
Inflammation	Altered Intercellular Communication	In the corpus mean scores increased in groups II-IV versus group I (P < 0.05 each), and aging was associated with a significant increase in bacterial density and active inflammation.	10192190
Inflammation	Altered Intercellular Communication	Antral inflammation decreases slightly in patients of advanced age.	10192190
Chronicity, Inflammation	Altered Intercellular Communication	These findings together with functional studies will contribute to the understanding of the pathogenesis of the chronicity of inflammation in these diseases.	10192196
Cataract, Inflammation, Uveitis	Altered Intercellular Communication	Chronic intraocular inflammation, with or without systemic inflammation, is associated with increased risk of cataract.	10192648
Cataract, Inflammation	Altered Intercellular Communication	Whether systemic inflammation alone is associated with cataract is unknown.	10192648
Cataract, Inflammation	Altered Intercellular Communication	This early report raises the possibility that systemic inflammation may play a role in the pathogenesis of age-related cataract.	10192648
Inflammation, Dermatitis, Atopic	Altered Intercellular Communication	Staphylococcal superantigens (SAG) are implicated in the inflammation of atopic dermatitis.	10193251
Dermatitis, Atopic, Genus staphylococcus, Inflammation, Conization	Altered Intercellular Communication	It is suggested that increased responses to SEB relate to increased colonisation and hence exposure to superantigen producing staphylococcus in atopic dermatitis, and that inflammation of atopic dermatitis is not caused by an inability to make antibody to SAG.	10193251
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Comparison of spontaneous and induced sputum for investigation of airway inflammation in chronic obstructive pulmonary disease.	10193394
Airway structure, ARCN1 gene, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Although sputum induction is used as a technique to investigate lower airway inflammation in asthmatic subjects, advantages over spontaneous sputum in patients with chronic obstructive pulmonary disease (COPD) have not been investigated.	10193394
Inflammation, diabetic	Altered Intercellular Communication	In contrast, the concentration of serum albumin was significantly lower (3180+/-499 mg/dl vs 3576+/-431 mg/dl, P<0.05), but six of the diabetic patients had signs of chronic inflammation.	10193815
Inflammation, diabetic	Altered Intercellular Communication	The lower albumin levels in the diabetic patients may be explained by a state of subclinical chronic inflammation.	10193815
Inflammation	Altered Intercellular Communication	Blinded histologic examination of laser-treated quadrants was performed to determine the amount of tissue ablation, residual thermal damage, inflammation, and new collagen synthesis.	10193958
Airway structure	Altered Intercellular Communication	Asthma, a family of airway disorders characterized by airway inflammation, has an increasing incidence worldwide.	10194471
Inflammation, Neoplasms	Altered Intercellular Communication	Angiogenesis is implicated in several pathological conditions, such as inflammation and tumor growth.	10194527
Airway structure	Altered Intercellular Communication	These patients suffer a high level of treatment and disease related morbidity but little is known about the degree of airway inflammation in these patients.	10195074
Inflammation, Atherosclerosis	Altered Intercellular Communication	Recent findings suggest that inflammation plays a role in atherosclerosis and its acute complications.	10195920
Gingivitis, Fracture, Tooth Fractures	Altered Intercellular Communication	The most common complications for titanium frameworks were resin or tooth fractures, gingival inflammation, and fractures of the metal frames (10%).	10196830
Basal cell hyperplasia, Inflammation, Atrophic, Cervical Transitional Metaplasia	Altered Intercellular Communication	The percentage of atrophy, basal cell hyperplasia, transitional metaplasia, chronic inflammation, and stromal proliferation was documented for each case in the benign group.	10197843
Inflammation, Stomach Carcinoma, Duodenal Ulcer, Gastric Ulcer, CTCAE 5, Atrophic	Altered Intercellular Communication	H. pylori density as well as grade of activity, inflammation and atrophy were significantly higher in the antrum than in the body in duodenal ulcer, while in chronic gastritis, gastric ulcer and gastric cancer there was no difference of H. pylori density, activity, inflammation and atrophy between the antrum and body.	10198601
Inflammation	Altered Intercellular Communication	The grade of activity and chronic inflammation were significantly higher in H. pylori positive patients than in H. pylori negative patients in both the antrum and body.	10198601
Inflammation	Altered Intercellular Communication	H. pylori seemed to be related to the development of chronic inflammation and activity.	10198601
Acute inflammation	Altered Intercellular Communication	Cooled intraocular irrigating solution reduced immediate postoperative inflammation compared with irrigating solution at room temperature.	10198865
Intraocular inflammation	Altered Intercellular Communication	The blood-ocular barrier undergoes direct assault with intraocular inflammation and the impermeability to blood-borne antibiotics is lost.	10198882
Inflammation, Neoplasms	Altered Intercellular Communication	We reviewed 280 endoscopic colorectal biopsy specimens for nonneoplastic disease from 100 consecutive patients in order to assess (a) the frequency of inflammation in excess of the physiologic infiltrate, (b) the frequency with which the cause of the inflammation could be specified, and (c) the interobserver variability in diagnosing inflammation.	10199471
Inflammation	Altered Intercellular Communication	Interobserver variability was greatest in biopsy specimens interpreted by the reviewers as normal or showing nonspecific changes, most of which had been diagnosed as mild inflammation by the original pathologists.	10199471
Inflammation, Neoplasms, Colitis	Altered Intercellular Communication	We conclude that (a) the majority of colorectal biopsy specimens from patients with nonneoplastic disease in this series show inflammation, (b) the majority of such cases allow a specific cause of colitis to be suggested or firmly diagnosed, and (c) pathologists tend to overdiagnose the physiologic inflammatory infiltrate as evidence of colitis and underdiagnose specific etiologic types of colitis.	10199471
Cessation of life, Inflammation, Systemic Inflammatory Response Syndrome, Organ Dysfunction Scores	Altered Intercellular Communication	Systemic inflammation (SIRS) and secondary organ dysfunction were the principal non-neurologic causes of death.	10199529
Inflammation, Thyroid associated opthalmopathies	Altered Intercellular Communication	As accumulation of negatively charged sulfate residues in GAG disaccharides results in enhanced water-binding capacity, beside inflammation and increased volume of the orbital adipose tissue, the altered structure and nature of sulfated GAG units in the orbit may be responsible for the pathogenic changes in Graves' ophthalmopathy.	10199787
Communicable Diseases, Sphenoid Sinusitis, Inflammation	Altered Intercellular Communication	Magnetic resonance imaging demonstrated diffuse pansinusitis, including sphenoid sinusitis, and extension of inflammation and infection into the adjacent cavernous sinuses, pituitary gland, and posterior fossa.	10201313
Inflammation, Gastritis, Infection caused by Helicobacter pylori, Esophagitis, Carditis, Intestinal metaplasia	Altered Intercellular Communication	In multivariate analysis, junctional SCE was independently and positively related to endoscopic erosive esophagitis (odds ratio [OR], 1.8; 95% confidence interval [CI], 1.1-3.1), cardia inflammation (carditis) (OR, 3.1; 95% CI, 1.4-6.8), and age (OR, 1.4 per decade; 95% CI, 1.2-1.6), but not to corpus H. pylori infection (OR, 1.4; 95% CI, 0.7-2.8), antral (OR, 1.0; 95% CI, 0.5-2.1) or corpus (OR, 0.8; 95% CI, 0.4-1.8) gastritis, or intestinal metaplasia of the antral mucosa in stomach (OR, 1.2; 95% CI, 0.7-2.1).	10201456
Intestinal metaplasia of gastric mucosa, Inflammation, Infection caused by Helicobacter pylori, Esophagitis	Altered Intercellular Communication	It is associated with cardia inflammation and endoscopic erosive esophagitis, but not with H. pylori infection or gastric intestinal metaplasia.	10201456
Inflammation, Episcleritis	Altered Intercellular Communication	To analyze patient characteristics and correlate between the site and severity of the inflammation and ocular and/or systemic disease association in a cohort of patients with episcleritis.	10201593
Inflammation, Disease	Altered Intercellular Communication	No significant correlation of the site and severity of inflammation to the presence of associated systemic or ocular diseases was found.	10201593
Inflammation, Diabetic Retinopathy	Altered Intercellular Communication	These results support the concept that inflammation may exacerbate diabetic retinopathy.	10201602
Granulomatous prostatitis, Prostate carcinoma	Altered Intercellular Communication	Granulomatous prostatitis is a benign inflammatory condition of the prostate which can be mistaken for prostatic carcinoma both clinically and on ultrasound, but is distinguishable histologically.	10201866
Inflammation, Allergic, Eosinophilic disorder, Fever, Mycoses	Altered Intercellular Communication	CSF eosinophilia without accompanying inflammation or pyrexia in the present case may have resulted from an allergic response to a foreign material such as the silicone tube pressure valve of the Sophy system or the sutures rather than bacterial or fungal infection.	10202300
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Cytokine-induced inflammation and long-term stroke functional outcome.	10202985
Inflammation, Ischemic stroke	Altered Intercellular Communication	We evaluated the association between cytokine-induced inflammation and functional outcome in 41 patients with acute ischemic stroke.	10202985
Inflammation, Asthma, Acute asthma	Altered Intercellular Communication	Serum eosinophil cationic protein (ECP) as a mediator of inflammation in acute asthma, during resolution and during the monitoring of stable asthmatic patients treated with inhaled steroids according to a dose reduction schedule.	10202995
Inflammation, Otitis Media with Effusion	Altered Intercellular Communication	Adenoid inflammation is implicated in the pathogenesis of OME and the adenoids have an important role in the cause of OME by being a reservoir for HI.	10203157
Arthralgia, Inflammation, Drug-induced lupus erythematosus, Inflammatory Bowel Diseases	Altered Intercellular Communication	To report four patients with antinuclear antibody-positive migratory arthralgias and acute inflammation unrelated to the underlying inflammatory bowel disease, fulfilling the criteria of a drug-induced lupus-like syndrome.	10203437
Inflammation, Fever, CTCAE, Hyperhidrosis, CTCAE, Communicable Diseases, Tachycardia by ECG Finding	Altered Intercellular Communication	Physical examination revealed a fever, tachycardia, and hyperhidrosis without any evidence of inflammation or infection.	10203975
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	The PLaseA2 that reacts with ethanolamine-containing phospholipids is more closely related to inflammation than other PLaseA2 isoenzymes in IBD mucosa.	10204610
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Levels of IL-6, IL-8, and TNF-alpha were significantly higher in active UC than in non-IBD colitis, and the production of all three of these cytokines was correlated to the endoscopic grade of inflammation.	10204613
Inflammation	Altered Intercellular Communication	Opioids may cause immediate local analgesia and also may work indirectly through decreasing the inflammation process.	10204724
Inflammatory disease of mucous membrane	Altered Intercellular Communication	MCP-3 staining was particularly pronounced at sites of active mucosal inflammation.	10205198
Inflammation, Gastrointestinal inflammation	Altered Intercellular Communication	MCP-3 production is substantially enhanced in areas of active inflammation, suggesting an immunoregulatory role of MCP-3 in intestinal inflammation.	10205198
BAP1 gene, Breast Carcinoma	Altered Intercellular Communication	We hypothesize that other genes, particularly those involved in endocrine signaling, may modify the BRCA1-associated age-specific breast cancer risk.	10205268
Inflammation, Tissue damage, Communicable Diseases, Malignant Neoplasms, Thrombocytosis	Altered Intercellular Communication	The most frequent causes of secondary thrombocytosis were tissue damage (42%), infection (24%), malignancy (13%) and chronic inflammation (10%).	10205592
Inflammation, Intraocular Route of Drug Administration	Altered Intercellular Communication	Potentialities of lymphotropic method of drug administration for arresting inflammation after intraocular cataract correction were studied in 60 patients aged 48-63 years.	10207315
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The level of enterocytes with electron-lucent cytoplasm containing a high amount of antigens was higher in CD and UC than in healthy mucosa, depending on the grade of inflammation.	10207729
Chronic heart failure, Cachexia	Altered Intercellular Communication	Cytokines and neurohormones relating to body composition alterations in the wasting syndrome of chronic heart failure.	10208789
Inflammation	Altered Intercellular Communication	A 64-year old woman presented with increased IOP and persistent anterior segment inflammation in her right eye.	10209730
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Reduced cholinergic transmission is a key neurotransmitter dysfunction in Alzheimer's Disease (AD).	10210264
Inflammation	Altered Intercellular Communication	Pathologic specimens obtained early after RF ablation revealed areas of focal acute inflammation and fibrin deposition.	10210495
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Fine needle aspiration cytology showed no signs of inflammation or malignancy.	10211354
Rett Syndrome, RETINOSCHISIS 1, X-LINKED, JUVENILE	Altered Intercellular Communication	To determine whether a disorder of excitatory neurotransmission plays a role in the pathophysiology of Rett syndrome (RS), N-methyl-D-aspartate (NMDA), adenosine monophosphate acid (AMPA), kainate, and metabotropic types of glutamate receptors were labeled autoradiographically in the superior frontal gyrus (SFG) from 9 RS patients and 10 female controls.	10211484
TAO brand of troleandomycin, Inflammation, Disorder of eye	Altered Intercellular Communication	Because of the possibility that such antibodies may play a role in orbital connective tissue inflammation in thyroid-associated ophthalmopathy (TAO), we studied the humoral immune response against specific extracellular matrix (ECM) proteins, namely: collagen types I, III, IV, V (CI, CIII, CIV, CV), fibronectin (FN), and laminin (LM).	10211607
Inflammation	Altered Intercellular Communication	In this respect, the CD97/CD55 pair may account for the specific architecture of the intimal lining layer and may be of primary importance in maintaining and amplifying synovial inflammation.	10211878
Granulomatous inflammation, Granulomatosis with polyangiitis	Altered Intercellular Communication	Cytokine profiles in Wegener's granulomatosis: predominance of type 1 (Th1) in the granulomatous inflammation.	10211889
Granulomatous inflammation	Altered Intercellular Communication	Our data indicate that a Thl cytokine pattern predominates in the granulomatous inflammation in patients with WG.	10211889
Inflammation, Extravasation, Pneumonia	Altered Intercellular Communication	To quantify the degree of capillary leakage during inflammation, the concentrations of the plasma proteins albumin, alpha1-antitrypsin, alpha2-macroglobulin and the locally produced proteins elastase, myeloperoxidase, lactoferrin and fibronectin were studied in the bronchoalveolar lavage (BAL) fluid of immunosuppressed children and adults with pneumonia.	10212109
Autoimmune Diseases, Lambert-Eaton Myasthenic Syndrome	Altered Intercellular Communication	Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disease that affects neurotransmitter release at peripheral synapses.	10212298
Inflammation	Altered Intercellular Communication	Patients with declining general status and laboratory evidence of inflammation, as well as those with new episodes of CCE, were treated with corticosteroids.	10213638
Inflammation, Lung Abscess	Altered Intercellular Communication	The lesion was resected by video-assisted thoracoscopic surgery because it was suspected of being a lung abscess that had caused repeated episodes of inflammation.	10214049
Appendix Perforation, CTCAE	Altered Intercellular Communication	The increase in leucocyte count was an early marker of appendiceal inflammation, whereas the CRP value increased markedly only after appendiceal perforation or abscess formation.	10215824
Inflammation, Necrosis	Altered Intercellular Communication	Blinded histological assessments showed improvement in the histological activity index (P =.007 for periportal necrosis,.001 for lobular necrosis, and.013 for portal inflammation).	10216146
Inflammation, Fibrosis Assessment, Cutis Laxa, Pathologic Neovascularization	Altered Intercellular Communication	AAA wall lesions were extensive, associating adventitial and medial fibrosis, elastolysis, smooth muscle rarefaction, neovascularization, inflammation and plaques.	10216430
Virus Diseases, Hepatitis B, Hepatitis, Chronic	Altered Intercellular Communication	Three cases of women with chronic liver inflammation caused by hepatitis B (two) and C (one) viral infections, were followed up to twelve years after diagnosis.	10216467
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	A growing body of evidence suggests a role for inflammation in acute coronary syndromes.	10217645
Inflammation, Hypertrophy	Altered Intercellular Communication	Comparative localization of MMP-3 and tenascin revealed intense staining for both in the synovial membrane presenting inflammation, proliferation and hypertrophy.	10218042
Granuloma, Inflammation, Low Vision, Traction detachment of retina, Juxtapapillary focal retinitis AND retinochoroiditis	Altered Intercellular Communication	There are different types of clinical progression: granuloma causing tractional detachment chronic inflammation called diffuse unilateral subacute neuroretinitis (DUSN) and rapid loss of vision named "ocular wipe-out syndrome".	10218207
Inflammation, Neuronal loss in central nervous system, Prion Diseases, Disease	Altered Intercellular Communication	Neuronal loss is a salient feature of prion diseases; however, its causes and mechanisms are unclear The possibility that it could occur through an apoptotic process has been postulated and is consistent with the lack of inflammation in prion disorders as supported by experimental studies.	10218627
Inflammation, Granulomatous mycosis fungoides	Altered Intercellular Communication	The unusually extensive granulomatous inflammation with huge giant cells surrounded by CD1a-positive cells in the other six biopsy specimens was suggestive of the histopathology of granulomatous slack skin, another rare granulomatous cutaneous T-cell lymphoma.	10218676
Inflammation	Altered Intercellular Communication	At day 7 the amount of inflammation was still elevated (mean flare increased 0.41 photons/ms from preoperative level with P<0.001 and mean cells increased 0.63 cells/0.5 mm3 from preoperative level with P<0.001).	10219027
Inflammation	Altered Intercellular Communication	Subclinical inflammation occurs in the non-operated eye following phacoemulsification and trabeculectomy.	10219027
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Inhibition of elastase-induced acute inflammation and pulmonary emphysema in hamsters by a novel neutrophil elastase inhibitor FR901277.	10219659
Hemorrhage, Ruptured simple cyst, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Histologically, the fibrous wall of the ciliated epithelial-lined cyst was thickened by non-caseating granulomatous inflammation, hemorrhage, hemosiderin, and cholesterol clefts, consistent with cyst rupture.	10219756
Hepatic inflammation, Necrosis	Altered Intercellular Communication	The serum levels of M-CSF increased after TACE in correlation with hepatic inflammation and necrosis and increased production of IL-1 beta, TNF-alpha and IL-6 in peripheral whole blood.	10220738
Inflammation	Altered Intercellular Communication	Elevated salivary IL-6 levels appear to be a consequence of local production and may reflect the component of salivary gland inflammation in SS.	10220831
Rheumatoid Arthritis	Altered Intercellular Communication	Anti-IL-8 autoantibodies and complexes in rheumatoid arthritis: polyclonal activation in chronic synovial tissue inflammation.	10220834
Refractory anemias, Inflammation, destruction joint	Altered Intercellular Communication	In the immune pathology of RA, it degenerates into a persistent chronic inflammation accompanied by progressive joint destruction.	10220834
Inflammation, Ocular Hypotension	Altered Intercellular Communication	No complication related to hypotony or inflammation occured in the post operative period.	10221187
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	No other risk factors, including those associated with diabetes mellitus, hemostasis, and inflammation, differed in their relative contribution to the two outcomes.	10221321
Inflammation	Altered Intercellular Communication	Nitric oxide (NO) is a free radical molecule endogenously produced by NO synthases that may play a critical role in inflammation.	10222219
Inflammation	Altered Intercellular Communication	In the analysis of 41 HAM/TSP patients, the neopterin levels were significantly correlated with the cell number and glucose levels in the CSF, and were a sensitive marker of inflammation.	10225668
Refractory anemias, Inflammation	Altered Intercellular Communication	Expression and secretion of MIP-1alpha by SF neutrophils may be indicative of local and systemic inflammation in RA.	10225815
Inflammation, Actinomycetoma, Specimen Source Codes - Abscess, Communicable Diseases, Specimen Type - Fistula	Altered Intercellular Communication	Typical actinomycetoma lesions, characterized by severe local inflammation with abscess and fistula formation, were fully established by day 28 after infection.	10225905
Inflammation	Altered Intercellular Communication	When the patient was discharged he was able to take food by mouth and the signs of inflammation subsided.	10226645
Respiratory Distress Syndrome, Adult, Inflammation	Altered Intercellular Communication	We hypothesized that since ferritin synthesis is increased by proinflammatory cytokines, which are increased and implicated in ARDS, that ferritin levels would increase and that ferritin increases would correlate with the degree of inflammation and therefore the development of ARDS.	10228118
Inflammation, Psoriasis	Altered Intercellular Communication	Thus, active tryptase could promote inflammation but chymase seems not to be an important mediator in the pathomechanism of psoriasis.	10228625
Gastrointestinal Hemorrhage, Pancreatitis	Altered Intercellular Communication	We report on a 29 year-old man with acute and severe gastrointestinal hemorrhage through the duct of an aberrant pancreas located in the upper jejunum, without clinical or histological evidence of pancreatic inflammation.	10228785
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Elevated concentrations of the acute-phase reactant C-reactive protein (CRP) predict ischemic cardiac events in both hospital- and population-based studies and may signify a role for inflammation in the destabilization of cardiovascular disease.	10229731
Inflammation, Ischemic stroke	Altered Intercellular Communication	These findings are consistent with a role for inflammation in acute ischemic stroke, as well as with the hypothesis that elevated CRP may predict future cardiovascular mortality.	10229731
Inflammation, Carcinoma, Meningitis, Labyrinthine disorder, Ear Inflammation	Altered Intercellular Communication	[Carcinoma of the nasopharynx, radiotherapy, otitis, labyrinthitis, inflammation of the petrous bone, meningitis].	10230088
Inflammation, Malnutrition, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	Strong association between malnutrition, inflammation, and atherosclerosis in chronic renal failure.	10231453
Cancer-related fatigue, Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	These results indicate that the rapidly developing atherosclerosis in advanced CRF appears to be caused by a synergism of different mechanisms, such as malnutrition, inflammation, oxidative stress, and genetic components.	10231453
Inflammation, TAPBP protein, human	Altered Intercellular Communication	Increasing serum concentration of group II PLA2 seems to reflect the ongoing systemic inflammation in severe AP-associated SIRS.	10231844
Necrotizing granulomatous inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Open lung biopsy showed histological findings of NSG, with epithelioid granulomatous inflammation, including giant cells, and vasculitis.	10232451
Angiolymphoid hyperplasia	Altered Intercellular Communication	After removal of the Castleman tumour, the skin and mucosal inflammation gradually subsided over the next 12 months.	10233229
Dacryoadenitis, Insufficiency	Altered Intercellular Communication	Does androgen insufficiency cause lacrimal gland inflammation and aqueous tear deficiency?	10235562
Sjogrens Syndrome", Inflammation, Insufficiency	Altered Intercellular Communication	Recently, others have hypothesized that androgen insufficiency induces an autoimmune process in lacrimal tissue, leading to inflammation, a Sjogren's syndrome-like pathology, and aqueous tear deficiency.	10235562
Sjogrens Syndrome", Dacryoadenitis, Dryness of eye, Meibomian gland dysfunction	Altered Intercellular Communication	Androgen deficiency may promote the progression of Sjogren's syndrome and its associated lacrimal gland inflammation, meibomian gland dysfunction, and severe dry eye.	10235562
Sjogrens Syndrome", Dacryoadenitis	Altered Intercellular Communication	However, androgen insufficiency alone does not cause lacrimal gland inflammation, a Sjogren's syndrome-like pathology in lacrimal tissue, or aqueous tear deficiency in nonautoimmune animals and humans.	10235562
Communicable Diseases, Inflammation	Altered Intercellular Communication	At reoperation there were no laboratory or intraoperative findings indicative of ongoing inflammation or infection.	10319633
Inflammation	Altered Intercellular Communication	[Wide spread inflammation of the parotid glands (mumps): underestimated disease.	10321083
Juvenile arthritis, Inflammation	Altered Intercellular Communication	Taken together these data suggest that some clones are actively excluded from inflamed sites in juvenile chronic arthritis, yet the pattern of restricted T cell expansion is shared between sites of inflammation.	10323206
Inflammation, Arthritis	Altered Intercellular Communication	Because asymptomatic C. trachomatis infections are frequent, and nonspecific reactions due to inflammation could be observed, this study was also performed with samples from healthy blood donors and from patients with inflammatory arthritis unrelated to C. trachomatis infection.	10323449
Inflammation	Altered Intercellular Communication	Control valves had a thin area of neutral lipid accumulation, a small amount of apoB, but no signs of inflammation.	10323772
Infection caused by Helicobacter pylori, Chronic gastritis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	All patients with chronic gastritis were in a hyperproliferative state related to mucosal inflammation, regardless of H pylori infection.	10323879
Inflammation, Infection caused by Helicobacter pylori, Genomic Instability, Metaplasia, Atrophic	Altered Intercellular Communication	Chronic H pylori infection seems to be responsible for genomic instability in a subset of cases of H pylori positive chronic atrophic gastritis; eradication of H pylori infection can reverse inflammation and the related atrophy, metaplasia, and genomic instability.	10323879
Intraocular inflammation, Endophthalmitis, CTCAE	Altered Intercellular Communication	Late-onset bleb-related endophthalmitis was defined as conjunctival injection, bleb purulence and intraocular inflammation developing at least 1 month following filtering surgery.	10325984
Conjunctivitis, Primary	Altered Intercellular Communication	A defective tear film, recurrent atopic keratoconjunctival inflammations, or a primary anomaly of corneal epithelial adhesion are potential causes for the corneal defects.	10326971
Abscess, Inflammation	Altered Intercellular Communication	The limit of the method essentially concerns abscesses with sclerous inflammation.	10327690
Inflammation, Intestinal Pseudo-Obstruction	Altered Intercellular Communication	Autoaggressive inflammation of the myenteric plexus resulting in intestinal pseudoobstruction.	10328094
Meningioma, Suppurative inflammation	Altered Intercellular Communication	Meningioma was diagnosed, and surgery was performed but was limited to biopsy because of intraoperative detection of purulent inflammation of the nodule.	10328548
Cataract, Pain Distress Question, Uveitis	Altered Intercellular Communication	Both treatments produced comparable reductions in intraocular inflammation and pain after cataract surgery and were well tolerated by patients.	10330648
Inflammation	Altered Intercellular Communication	[The ultrastructural characteristics of the bronchial mucosa in chronic inflammation in participants in the cleanup of the aftermath of the accident at the Chernobyl Atomic Electric Power Station].	10330694
Upper Respiratory Infections	Altered Intercellular Communication	Our results suggest that secreted HGF may play an important role in bronchial epithelium reconstruction during respiratory inflammation.	10330798
allergic inflammation	Altered Intercellular Communication	The corticosteroid is effective for treating allergic inflammation.	10331302
Fracture	Altered Intercellular Communication	These were most commonly fractures, sprains, strains, and inflammation/oedema.	10332002
Cessation of life, Inflammation, Pleurisy, Occipital headache	Altered Intercellular Communication	In the present case, although the original inflammation was left pleuritis due to Streptococcus pneumoniae, correct clinical diagnosis was not made before death as the patient had lacked any complaints except for occipital headache.	10332185
Inflammation	Altered Intercellular Communication	The two lesions observed in the present case may be interpreted as caused by inflammation of the connective tissue initially either at the vertebrae or around the aorta, which had advanced to involve the other lesion.	10332212
Inflammation, Endothelial dysfunction, Diabetes Mellitus	Altered Intercellular Communication	Our objective was to evaluate whether selected hemostasis variables, some of which may reflect inflammation or endothelial dysfunction, are independently associated with the development of diabetes.	10332679
Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	These findings support a role for inflammation and, particularly in women, endothelial dysfunction in the pathogenesis of type 2 diabetes.	10332679
Ovarian, Ovarian Follicle	Altered Intercellular Communication	Supporting this hypothesis, in patients with normal or irregular menses, the presence of this antibody was associated with elevated serum level of follicle stimulating hormone, an early and specific sign of ovarian lesion.	10332973
Inflammation, Hyperplasia	Altered Intercellular Communication	Neuroidal melanocytic structures, invasion of adventitial dermis, islands of inflammation, and epidermal lentiginous melanocytic hyperplasia were often present.	10333224
Seasonal Affective Disorder, Sandawe language	Altered Intercellular Communication	There is some evidence that the neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) may be involved in the pathogenesis of seasonal affective disorder (SAD).	10333377
Paraproteinemias, Necrobiotic Xanthogranuloma	Altered Intercellular Communication	The subsequent demonstration of IgG lambda paraproteinaemia and the histological features of necrobiotic xanthogranulomatous inflammation confirmed the clinical diagnosis of necrobiotic xanthogranuloma with paraproteinaemia.	10333627
Lung diseases, Scleroderma , Hamman-Rich syndrome, Interstitial inflammation	Altered Intercellular Communication	Interstitial inflammation is a major aggravating factor in fibrosing lung disease associated with scleroderma (FASSc) and cryptogenic fibrosing alveolitis (CFA).	10334152
Inflammation, Asthma, Bronchiectasis	Altered Intercellular Communication	Exhaled nitric oxide (NO) production is increased in asthma and bronchiectasis and reflects the degree of inflammation.	10334152
Cessation of life, Inflammation	Altered Intercellular Communication	Recent research demonstrates that apoptosis (programmed cell death) in inflammatory cells is an important factor in the resolution of inflammation, and apoptosis is induced in eosinophils in cell culture with steroids.	10334231
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	Synovial membrane volumes were poorly related to the presence of rheumatoid factor and to laboratory markers of inflammation.	10334685
Inflammation, Hepatitis, Bile acid measurement	Altered Intercellular Communication	It is proposed that bile acid retention in bile ducts during non-specific reactive inflammation or a gut endotoxin may cause transformation of Ito cells and increased collagen type III and IV in this type of hepatitis.	10335364
Inflammation, Diabetes Mellitus, Atherosclerosis	Altered Intercellular Communication	Markers of inflammation and prediction of diabetes mellitus in adults (Atherosclerosis Risk in Communities study): a cohort study.	10335783
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Coronary heart disease	Altered Intercellular Communication	Since markers of inflammation predict coronary heart disease and are raised in patients with type 2 diabetes, we investigated whether they predict whether people will develop type 2 diabetes.	10335783
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	We analysed the association between different markers of acute inflammation and subsequent diagnosis of diabetes.	10335783
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Markers of inflammation are associated with the development of diabetes in middle-aged adults.	10335783
Neurodegenerative Disorders	Altered Intercellular Communication	Glutamate is the major excitatory neurotransmitter in the central nervous system and is implicated in the pathogenesis of neurodegenerative diseases.	10336123
Inflammation	Altered Intercellular Communication	With the exception of Dpyd levels in urine which only show a tendency to correlate with ESR, there are positive correlations between measured crosslink-levels in urine and markers of inflammation.	10336408
Inflammation, Glomerulonephritis	Altered Intercellular Communication	Leukotrienes (LT) of the 5-lipoxygenase pathway constitute a class of potent biological lipid mediators of inflammation implicated in the pathogenesis of different models of experimental glomerulonephritis.	10337029
Inflammation, Vertigo, hearing impairment, No ocular symptoms, Nausea	Altered Intercellular Communication	The patient presented with persisting inflammation of the right auricle, sudden lower-frequency hearing loss, acute moderate vertigo with nausea and mild ocular symptoms.	10337505
Inflammation, Angina, Unstable	Altered Intercellular Communication	Inflammation, endothelial cell function and the coagulation system have been demonstrated to be involved in the onset and course of unstable angina.	10337541
Inflammation, Angina, Unstable	Altered Intercellular Communication	Markers of inflammation, coagulation activation and endothelial cell function were determined on admission in blood of 211 consecutive patients with severe unstable angina and were related to the in-hospital course.	10337541
Inflammation	Altered Intercellular Communication	The data strengthen the importance of inflammation in this syndrome.	10337541
Infection	Altered Intercellular Communication	Inflammatory conditions and infections were the most frequently observed diseases.	10337597
Inflammation	Altered Intercellular Communication	At the second endoscopy after medication regimen for eradication of H. pylori, inflammation was decreased and the rapid urease test was negative.	10337933
Orbital Pseudotumor, Allergic Conjunctivitis	Altered Intercellular Communication	This case demonstrates that orbital inflammation can be misdiagnosed as refractory allergic conjunctivitis.	10340792
Inflammation	Altered Intercellular Communication	Biological markers of inflammation were significantly more increased in the biopsy proven group.	10340957
Arthritis	Altered Intercellular Communication	Disease outcome was measured by Health Assessment Questionnaire (HAQ) score and C-Reactive Protein (CRP) as a serological measure of joint inflammation.	10342023
Inflammation, Autoimmune reaction	Altered Intercellular Communication	The results suggest that these soluble markers may represent potentially useful parameters to monitor disease activity or chronic inflammation in certain types of autoimmune uveitis.	10342043
Inflammation, Thrombosis, Necrosis	Altered Intercellular Communication	Skin and cervical biopsies revealed acute inflammation involving through-and-through necrosis of vessel walls with thrombosis, focal fibrinoid change, and a perivascular lymphohistiocytic infiltrate.	10342897
Chronicity, Inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	It is hypothesised that these factors may play a part in the overall impaired immune function and in the chronicity of inflammation in SLE.	10343529
Inflammation, Acute myocardial infarction, Tumor necrosis	Altered Intercellular Communication	Inflammation plays a critical role in acute myocardial infarction (AMI) and tumor necrosis factor alpha (TNF-alpha) is a potent inflammatory trigger.	10347344
Mouth Diseases, Inflammation	Altered Intercellular Communication	The findings suggest that defensin-1 in saliva may be a convenient marker of inflammation associated with oral disease.	10348509
Inflammation, Fibrosis Assessment, Balloon Dilatation	Altered Intercellular Communication	All liver biopsy specimens from 1979 to 1987 with fat accumulation were assessed for inflammation, ballooning degeneration, Mallory hyaline, and fibrosis.	10348825
Inflammation, Vulva	Altered Intercellular Communication	The authors describe a unique case of isolation of Neisseria meningitidis C:2a:P1.2,P1.5 in August 1997 from a 7-year-old female patient from a vaginal smear during purulent inflammation of the external genital following injury.	10349780
Intestinal metaplasia, Inflammation, Helicobacter heilmannii, Gland	Altered Intercellular Communication	Hematoxylin- and eosin-stained sections from 6 patients with Helicobacter heilmannii (18 biopsies) and 23 randomly selected patients with H. pylori (68 biopsies) were evaluated and semiquantitated for the presence of acute inflammation, chronic inflammation, glandular atrophy, intestinal metaplasia, H. pylori, H. heilmannii, lymphoid follicles, or vasodilatation.	10349993
Inflammation, Hemolysis (biological function), Blood Coagulation Disorders	Altered Intercellular Communication	These changes may be due to hemolysis, consumption coagulopathy or inflammation associated with acute aortic dissection.	10350101
Inflammation, Berylliosis	Altered Intercellular Communication	We investigated the antioxidant response of the lungs to the chronic release of ROS, as occurs in the immune-specific granulomatous inflammation of chronic beryllium disease (CBD), and compared it with that in healthy controls and individuals exposed to cigarette smoke.	10351926
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Thus, coordinate augmentation of the glutathione antioxidant system occurs in granulomatous lung inflammation.	10351926
Inflammation, Edema, Clostridium difficile colitis	Altered Intercellular Communication	The accordion sign is indicative of severe colonic edema or inflammation, but it is not specific for C difficile colitis.	10352600
Sepsis, Inflammation	Altered Intercellular Communication	Outcome prediction by traditional and new markers of inflammation in patients with sepsis.	10353484
Sepsis, Communicable Diseases, Inflammation	Altered Intercellular Communication	These data indicate that PCT might be a better marker than the classic criteria of inflammation, CRP, leukocyte count, and body temperature to identify patients endangered by severe infection or sepsis.	10353484
Helicobacter pylori, Gastritis	Altered Intercellular Communication	Helicobacter pylori induces gastric inflammation and the the production of cytokines in infected individuals.	10353980
Inflammation, BDP1 wt Allele	Altered Intercellular Communication	Clinical features of lesions associated with a higher FNR were lack of irregular pigmentation and shape, altered sensation, the presence of inflammation and size < 7 mm.	10354030
Chlamydia, Aortic Aneurysm, Abdominal, Glucocorticoid deficiency with achalasia	Altered Intercellular Communication	The presence of Chlamydia pneumoniae in the walls of abdominal aortic aneurysms (AAAs) has been demonstrated recently, but its role in the cause and/or maintenance of aortic wall inflammation is not known.	10354217
Inflammation, Glaucoma, CTCAE, "Crohns disease of large bowel	Altered Intercellular Communication	The intraocular recurrence often was heralded by the onset of low-grade inflammation and secondary glaucoma, simulating a granulomatous iridocyclitis.	10355832
Inflammation	Altered Intercellular Communication	In conclusion, lactoferrin is a reliable marker of neutrophil activation at sites of inflammation in rheumatoid synovitis, but does not represent a marker of disease activity.	10356661
Inflammation, Disease	Altered Intercellular Communication	Contrary to other diseases, in non-specific intestinal inflammations the erythropoietin secretion depends not only on the severity of the inflammation but probably on many other factors, incl.	10358447
Inflammation	Altered Intercellular Communication	In 39 patients with non-specific intestinal inflammations the authors examined the erythropoietin level.	10358447
Inflammation, Disease	Altered Intercellular Communication	Contrary to other diseases, in non-specific intestinal inflammations the erythropoietin secretion depends not only on the severity of the inflammation but probably on many other factors, incl.	10358447
Inflammation, Ischemic stroke	Altered Intercellular Communication	[Clinico-immunobiochemical monitoring of factors of focal inflammation in the acute period of hemispheric ischemic stroke].	10358915
Inflammation, Fibrosis Assessment, Hyperplasia, Papilledema	Altered Intercellular Communication	Based both on the absence of cellular atypia and the presence of inflammation, fibrosis, and preservation of the normal architecture of the ampulla, we favor the interpretation that this hyperplastic lesion represents a sequela of chronic papillitis.	10359853
Inflammatory abnormality of the eye, Vitreous humor	Altered Intercellular Communication	Characterization of phenotype and cytokine profiles of T cell lines derived from vitreous humour in ocular inflammation in man.	10361227
Communicable Diseases, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	In addition, mPR3+ phenotypes were normally distributed in cystic fibrosis patients, indicating that infection and/or inflammation per se do not lead to a high percentage of mPR3+ neutrophils.	10361860
Inflammation, Inflammatory disorder, Cardiovascular Diseases	Altered Intercellular Communication	We conclude that it is crucial to reduce inflammation pre- and postoperatively, to reinforce the suture line, and to carefully select the operative procedures when treating cardiovascular disorders caused by inflammatory diseases.	10363610
Inflammation, Atherosclerosis	Altered Intercellular Communication	Chronic inflammation is linked to atherosclerosis and Helicobacter pylori has been suggested to be an etiologic agent, although the evidence is equivocal.	10363881
Inflammation	Altered Intercellular Communication	Magnetic resonance imaging (MRI) was used to describe the anatomical structures affected by inflammation in pure RS3PE syndrome.	10364902
Granulomatous inflammation, Granulomatosis with polyangiitis, Vasculitis, CTCAE, Inflammatory disorder	Altered Intercellular Communication	Wegener's granulomatosis (WG) is an inflammatory disorder characterised by granulomatous inflammation, vasculitis, and necrotising vasculitis and is strongly associated with anti-neutrophil cytoplasmic antibodies (ANCA).	10364903
Inflammation	Altered Intercellular Communication	The results suggest that SF HAase activity could be used as a marker of synovial inflammation.	10364918
Vasculitis, vascular inflammations	Altered Intercellular Communication	Differences with results previously found in patients with other vasculitides may indicate that different pathogenic mechanisms contribute to vascular inflammation in different disorders.	10364919
Inflammation, Thrombosis	Altered Intercellular Communication	Mean and median CRP levels were higher in thrombosis patients than in the controls, suggesting inflammation in some patients.	10365736
Inflammation	Altered Intercellular Communication	These results show that although systemic inflammation may be present in some of the patients, elevated levels of factor VIII:C and fibrinogen were in general not caused by acute phase reactions.	10365736
Cataract, Acute inflammation	Altered Intercellular Communication	To evaluate the safety and efficacy of an intraocular biodegradable polymer dexamethasone drug delivery system (DEX DDS) in treating postoperative inflammation after cataract surgery.	10366088
Cataract, Acute inflammation	Altered Intercellular Communication	The DEX DDS was safe and effective in suppressing postoperative inflammation after uncomplicated cataract surgery.	10366088
Hyperthyroidism, Thyrotroph adenoma, Aggressive behavior, Neoplasms	Altered Intercellular Communication	The main points arising were that: (1) high or normal plasma TSH associated with an increase in plasma alpha-subunit and high thyroid hormone levels is the best criterion for diagnosis; (2) the failure of TSH to respond to TRH or Werner's test is not a reliable criterion for diagnosis; (3) thyrotropic adenomas may be 'silent', without clinical signs of hyperthyroidism and with only slight increase in TSH, tri-iodothyronine and thyroxine concentrations; (4) mitoses and nuclear atypies are frequently detected in large tumors, which are invasive in more than 50% of cases - the first analysis of two proliferation markers (PCNA and Ki-67) bears out the relative aggressiveness of thyrotropic adenomas; (5) thyrotropic adenomas are frequently plurihormonal.	10366408
Adenocarcinoma, Inflammation, Endometrial intraepithelial neoplasia, Squamous Dysplasia	Altered Intercellular Communication	Initial cervical biopsies showed adenocarcinoma in situ and/or glandular dysplasia in 28 (70%), squamous dysplasia in 2 (5%), chronic inflammation in 2 (5%), and no pathologic changes in 2 (5%) patients.	10366458
Inflammation, Perivascular lymphocytic infiltrations	Altered Intercellular Communication	Open biopsy revealed noncaseating granulomatous inflammation and perivascular lymphocytic infiltration.	10367488
Inflammation	Altered Intercellular Communication	No interferences of the assay were observed in patients with acute inflammation and highly increased ACT concentrations.	10367846
Inflammation	Altered Intercellular Communication	We conclude that anti-TNFalpha produces an obvious resolution in inflammatory joint activity that is accompanied by an increased circulating component of the total blood granulocyte pool, as a result of decreased margination at sites of inflammation.	10369798
Inflammation, Leukocytosis	Altered Intercellular Communication	The rate of conversion (44.9%) correlated with the severity of inflammation, which was determined on the basis of leukocytosis > 10 x 10(9)/l (p = 0.004) and the pathohistological diagnosis (p = 0.005).	10370605
Inflammation, Rheumatoid Arthritis, "5-NUCLEOTIDASE	Altered Intercellular Communication	5'-Nucleotidase as a marker of both general and local inflammation in rheumatoid arthritis patients.	10371274
Refractory anemias, Inflammation, Arthritis, Rheumatoid Arthritis	Altered Intercellular Communication	To evaluate measurements of serum and synovial fluid 5'-nucleotidase (5'N) activity as a marker of general and local inflammation in arthritis, and to resolve a contradiction in the literature as to whether or not the activity of 5'N in the synovial fluids of rheumatoid arthritis (RA) patients is raised in comparison with that in the synovial fluids of other arthritis patients.	10371274
Refractory anemias, Inflammation, Arthritis	Altered Intercellular Communication	The 5'N activity in the serum (which came mostly from the liver) could be used as a marker of general inflammation, whereas the 5'N in the synovial fluid was mostly produced locally, and could be used as a marker of joint inflammation, particularly for the RA patients.	10371274
Inflammation, Disease	Altered Intercellular Communication	The possibility that it could occur through an apoptotic process has been postulated and this is consistent with the lack of inflammation in prion disorders as supported by experimental studies.	10371778
Inflammation, Acute Coronary Syndrome, Infection	Altered Intercellular Communication	Inflammation and possibly chronic infections are associated with acute coronary syndromes; however, the mechanisms responsible for this association are not yet fully elucidated.	10371790
Calcified (qualifier), Inflammation, Cyst	Altered Intercellular Communication	The prevalence of structural abnormalities, including calcifications, nodules, cysts, and vesicle inflammation, was significantly increased in patients compared to controls (78.2% vs. 23.3%; chi2 = 5.856; P < 0.05).	10372698
Communicable Diseases, Inflammation	Altered Intercellular Communication	Infection is generally associated with vaginal discharge and moderate or severe inflammation.	10373139
Malignant tumor of colon, Inflammation	Altered Intercellular Communication	For instance a frequent difficult issue in colon cancer is the presence of ulceration and adjacent severe inflammation which by itself can increase vascularity.	10373667
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	There were invasion of lymphocytes, inflammation edema, and fibroelastosis around cancer cells as well.	10374554
Inflammation, Hyponatremia	Altered Intercellular Communication	We experienced four cases with hyponatremia due to SIADH, which seems to be related to inflammation.	10375961
Inflammation	Altered Intercellular Communication	These results suggested that the interleukin play an important role in the development of SIADH associated with inflammation.	10375961
Inflammatory abnormality of the eye, Abnormally opaque structure (morphologic abnormality), Corneal Diseases	Altered Intercellular Communication	Eyes with refractive error exceeding 5.0 D sphere or 2.0 D cylinder, nonlenticular media opacity, cup-to-disc ratio > 0.9, corneal disease, ocular inflammation, or previous intraocular surgery were excluded.	10376254
Postoperative Period, Acute inflammation	Altered Intercellular Communication	Occurrence of pops also is associated with more severe postoperative inflammation and with a greater risk of postoperative hyphema.	10376257
Inflammation	Altered Intercellular Communication	Since PPARalpha activators, which are hypolipidemic drugs, are being prescribed for a significant population of older patients, it is important to determine the impact of these drugs on the host response to acute inflammation.	10377130
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Since chronic obstructive pulmonary disease (COPD) is characterised by airway inflammation, a study was undertaken to determine NO levels in the exhaled air of patients with COPD.	10377199
Airway structure, ARCN1 gene	Altered Intercellular Communication	The close association between exhaled NO levels and sputum eosinophils suggests a role for NO in airway inflammation in COPD.	10377200
Congestive heart failure	Altered Intercellular Communication	In congestive heart failure (CHF) such failure of hormonal suppression is associated with increased mortality.	10377310
Inflammation, Kaposi Sarcoma, Vasculitis, CTCAE	Altered Intercellular Communication	Magnetic resonance images were consistent with multiple hemorrhagic infarcts, areas of inflammation, or both, and cerebral angiography showed changes consistent with vasculitis.	10380138
Inflammation	Altered Intercellular Communication	Laboratory tests showed inflammation and a modest isolated peak of monoclonal IgM kappa.	10380261
Acute and chronic inflammation, Wounds and Injuries, Oral Manifestations, Neoplasms	Altered Intercellular Communication	The pathologic processes involving the parotid gland area include a vast, heterogeneous group of lesions, consisting of dysembryopathies, traumas, acute and chronic inflammation, degenerative manifestations, benign tumours and both primary and secondary malignancies.	10380365
Inflammation, Intrapulmonary teratoma	Altered Intercellular Communication	The resected specimen revealed an intrapulmonary hematoma with severe inflammation.	10380476
Refractory anemias, Rheumatoid Arthritis, Arthritis, Degenerative polyarthritis	Altered Intercellular Communication	To investigate serum derived hyaluronan (HA) associated protein-hyaluronan (SHAP-HA) complex in sera from patients with rheumatoid arthritis (RA) and osteoarthritis (OA) and determine levels of the complex in comparison with those of hyaluronan (HA), in order to assess the role of the complex as an indicator of joint inflammation.	10381035
Refractory anemias, Inflammation, Arthritis	Altered Intercellular Communication	Quantitation of the SHAP-HA complex in sera may be useful as a joint marker that directly correlates to the degree of joint inflammation in RA, and offers new insight into the pathogenesis of arthritis.	10381035
Hearing problem, Inflammatory abnormality of the eye, Vasculitis, CTCAE, Oculovestibuloauditory syndrome	Altered Intercellular Communication	Cogan's syndrome is a rare multisystem disease characterized by ocular inflammation, vestibuloauditory dysfunction, and vasculitis.	10381065
Inflammation	Altered Intercellular Communication	Secretory non-pancreatic (group II) phospholipase A2 (sPLA2) releases precursors of important mediators of inflammation from phospholipids.	10381280
Degenerative polyarthritis, Inflammation, Refractory anemias	Altered Intercellular Communication	Clinical assessment of inflammation (0-6) was undertaken on OA and RA knees.	10381489
Amyotrophic Lateral Sclerosis, Respiratory Failure	Altered Intercellular Communication	Syndrome of inappropriate secretion of antidiuretic hormone associated with amyotrophic lateral sclerosis in respiratory failure.	10382239
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Histologic examination of the excised specimen showed chronic granulomatous inflammation, and subsequent microbiologic studies cultured an acid- and alcohol-fast bacillus that was later identified as Mycobacterium fortuitum.	10382255
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	Thus, RANTES and MIP-1alpha were suggested to be important in the pathogenesis of granulomatous inflammation in sarcoidosis and HP.	10384061
Fibrinoid necrotizing inflammation	Altered Intercellular Communication	Multiple regression analysis revealed that the serum C-reactive protein value was better correlated with the linear combination of SF TNF-alpha and SF TRX values than with SF TNF-alpha alone, suggesting that TRX might play a subsidiary role in the rheumatoid inflammation.	10384135
Refractory anemias, Fibrinoid necrotizing inflammation	Altered Intercellular Communication	These findings indicate that the elevated TRX concentration in SF of RA patients might be involved in the aggravation of rheumatoid inflammation by augmenting the NF-kappaB activation pathway.	10384135
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	The chronic immune response in rheumatoid arthritis (RA) might be driven by activated Th1 cells without sufficient Th2 cell differentiation to down-modulate inflammation.	10384153
Refractory anemias, Inflammation	Altered Intercellular Communication	To test whether disordered memory T cell differentiation contributes to the typical Th1-dominated chronic inflammation in RA we investigated differentiation of resting CD4+ memory T cells in patients with early (6 wk to 12 mo) untreated RA and in age- and sex-matched healthy controls in vitro.	10384153
Refractory anemias, Inflammation	Altered Intercellular Communication	The data suggest that CD4+ memory T cells from patients with early untreated RA manifest an intrinsic abnormality in their ability to differentiate into specific cytokine-producing effector cells that might contribute to the characteristic Th1-dominated chronic (auto)immune inflammation in RA.	10384153
Inflammation, Gingival Overgrowth	Altered Intercellular Communication	The rats showed no sign of gingival inflammation (mean gingival index = 0) or gingival overgrowth (mean gingival overgrowth index = 0).	10384402
Rheumatoid Arthritis, Sicca Syndrome	Altered Intercellular Communication	No association of sicca symptoms was found with rheumatoid arthritis, smoking, alcohol consumption, reproductive hormonal status, or the presence of autoantibodies.	10386512
Inflammation	Altered Intercellular Communication	There was also marked chronic inflammation in and around the mass.	10388922
Saint Lucia, Hepatitis, Liver Dysfunction	Altered Intercellular Communication	These levels reflect hepatic dysfunction better than liver inflammation parameters, which might explain the higher serum concentrations of cytokines in LC patients.	10389289
Inflammation, Colonization, Gastritis, Intestinal metaplasia, Atrophic	Altered Intercellular Communication	The Sydney classification system of gastritis was used, using a score of 0-3 to grade degree and activity of inflammation, gland atrophy, intestinal metaplasia, and H. pylori colonization density.	10389688
Inflammation	Altered Intercellular Communication	Histologically, a dense inflammation chiefly composed of lymphocytes and plasma cells with few neutrophils was detected.	10389695
ACSM3 gene, Inflammation	Altered Intercellular Communication	In comparison with 27 age-matched non-SAH controls, the authors observed blood and inflammation within the arachnoid villi during the 1st week after SAH.	10389884
Granulomatous inflammation, Granulation finding	Altered Intercellular Communication	Two of the cases were considered to be non-diagnostic due to hypocellularity, while two cases containing cellular material raised the differential diagnosis of granulation tissue and granulomatous inflammation due to the presence of epithelioid cells and an inflammatory infiltrate, and are illustrated here.	10390067
Inflammation, Necrosis	Altered Intercellular Communication	Plaque instability was assessed by the presence or absence of a large, necrotic, lipid core; a thin, fibrous cap; and superficial inflammation.	10390302
Respiratory Distress Syndrome, Adult, Inflammation, Drug toxicity, Hypoxemia	Altered Intercellular Communication	One year after ARDS a substantial portion of ARDS survivors exhibit impaired health status and cognitive sequelae which may be due to hypoxemia, emboli, inflammation, drug toxicity, and/or other etiologies.	10390379
Inflammation, Septic Shock	Altered Intercellular Communication	A significant correlation was observed between plasma AM and TNF-alpha levels in patients with septic shock, suggesting an important role for AM as well as of TNF-alpha in the pathophysiology of inflammation.	10390390
Hepatitis, Necrosis with inflammation	Altered Intercellular Communication	Histopathologic features were as follows: (1) inflammation-related cell infiltration scattered within the portal area, with distinguishable necroinflammation in the lobular region; (2) pathologic findings on biliary epithelium; (3) high incidence of steato-metamorphosis involvement; and (4) histologic characteristics undistinguishable from "viral" chronic hepatitis in some liver specimens.	10390996
Necrotizing granulomatous inflammation	Altered Intercellular Communication	In microscopic picture of enlarged lymph nodes non specific inflammation granulomatosis was found but microbiological examinations were not done.	10391958
Angiectasis, Inflammation, Edema, Foveolar hyperplasia, Muscle (organ)	Altered Intercellular Communication	Foveolar hyperplasia, edema, muscular stranding, vascular ectasia, and active and chronic inflammation were semiquantitatively graded.	10392635
Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Although the association between inflammation and atherosclerosis is well established, the biologic events that trigger the local inflammatory response within plaque are not fully understood.	10394152
Inflammation, Fibrosis Assessment, Fatty infiltration	Altered Intercellular Communication	Biopsy showed fatty infiltration of nearly all the hepatocytes, without significant inflammation and fibrosis.	10394349
Chronic inflammation	Altered Intercellular Communication	Insufficient T cell apoptosis may interfere with clonal deletion and maintenance of tolerance, and result in inappropriate T cell accumulation contributing to chronic inflammation.	10395708
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation is infrequently encountered in skeletal muscle biopsy material.	10396287
Granulomatous inflammation	Altered Intercellular Communication	Of 2,985 muscle biopsy specimens reviewed over 12 years, 12 (0.4%) with granulomatous inflammation were identified.	10396287
Inflammation, Sarcoidosis, Granulomatous, Muscle fiber atrophy	Altered Intercellular Communication	In conclusion, granulomatous myositis is infrequently found in muscle biopsy specimens (0.5% of all biopsies in this series); most muscles demonstrate evidence of chronic endomysial or perivascular inflammation accompanied by muscle fiber degeneration and regeneration; and the most common cause for granulomatous myositis was sarcoidosis in this series.	10396287
Paranasal Sinus Disorder, physiopathological, Orbital Pseudotumor	Altered Intercellular Communication	When a patient presents with signs of optic nerve dysfunction and orbital inflammation the significance of widespread sinus disease on radiology is clear and the management is straightforward.	10396389
Eosinophilic disorder, Inflammatory disease of mucous membrane, Allergy - Charge Type Reason	Altered Intercellular Communication	Idiopathic maxillary pain: prevalence of maxillary sinus hyperreactivity in relation to allergy, chronic mucosal inflammation, and eosinophilia.	10397658
Eosinophilic disorder, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Comparison of the data showed most patients (38%) to have an absence of chronic maxillary sinusitis-related diagnoses, whereas the most common multiple diagnosis was found to be chronic mucosal inflammation in combination with eosinophilia (22%).	10397658
Eosinophilic disorder, Inflammatory disease of mucous membrane, Allergy - Charge Type Reason	Altered Intercellular Communication	Regarding the prevalence rates of positive histamine provocation test outcomes, a significant difference was found between the diagnostic subgroup "absence of chronic maxillary sinusitis-related diagnoses" (36.9%) and the diagnostic subgroups "chronic mucosal inflammation" (20%; P< .05), "chronic mucosal inflammation in combination with eosinophilia" (18.2%; P< .05), and "chronic mucosal inflammation in combination with eosinophilia and allergy" (14.3%; P < .01).	10397658
Eosinophilic disorder, Chronic maxillary sinusitis, Allergy - Charge Type Reason	Altered Intercellular Communication	An analysis of the distribution of chronic maxillary sinusitis-related diagnoses revealed absence of chronic mucosal inflammation-related diagnoses to be significantly more frequently associated with positive histamine provocation test outcomes than with negative histamine provocation test outcomes (41.2% vs 19.7%; P< .01), whereas chronic maxillary sinusitis (41.0% vs 29.4%), eosinophilia (26.2% vs 17.6%), and allergy (13.1% vs 11.8%) were found to be more prevalent in patients with negative histamine provocation test outcomes.	10397658
Eosinophilic disorder, Inflammatory disease of mucous membrane, Allergy - Charge Type Reason	Altered Intercellular Communication	The findings of this study suggest patients with idiopathic maxillary pain to be associated with a low rate of sinus hyperreactivity, whereas a positive test outcome with histamine provocation may not be linked to the presence of chronic maxillary sinusitis-related diagnoses such as allergy, chronic mucosal inflammation, and eosinophilia.	10397658
Inflammation, Atherosclerosis	Altered Intercellular Communication	Our results indicate that n-3 FA supplementation decreases hemostatic markers of atherosclerosis, whereas markers of inflammation may be increased.	10397685
Refractory anemias, Inflammation, Metabolic acidosis	Altered Intercellular Communication	Inflammation in RA is running with lowering of JF pH in the affected joints and with acidic shift in the acid-base balance manifesting as compensated metabolic acidosis in blood.	10399224
Inflammation	Altered Intercellular Communication	JF pH of the affected joints inversely correlated with activity of the inflammation.	10399224
Refractory anemias, Inflammation	Altered Intercellular Communication	JF pH may be used for assessment of inflammation activity in RA.	10399224
Inflammation	Altered Intercellular Communication	Cytologic examination of fluid collected from the mass repeatedly showed acute inflammation.	10399453
Acute necrotizing inflammation, Disease, Necrosis	Altered Intercellular Communication	The hallmark of the disorder is an acute necrotizing inflammation of the vessel media with fibrinoid necrosis.	10399798
Inflammation	Altered Intercellular Communication	However, the etiology and cellular mechanism of chronic inflammation are poorly understood in HAM/TSP.	10399866
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Positive magnetic resonance imaging or computed tomography findings compatible with inflammatory tissue neither exclude nor confirm THS and remain suspect until a malignant tumor or inflammation other than THS is excluded.	10399869
Inflammation	Altered Intercellular Communication	ASTLL may be an interesting tool to detect subclinical gut inflammation in patients with SpA.	10402075
Refractory anemias, Inflammation, Rheumatoid Arthritis, Autoradiographic Image	Altered Intercellular Communication	To study the localization and cell type-specific expression of collagenase 3 messenger RNA (mRNA) in the synovial membrane, its regulation in primary synovial fibroblasts, and the correlation with systemic markers of inflammation and radiographic damage in rheumatoid arthritis (RA).	10403281
Refractory anemias, Inflammation	Altered Intercellular Communication	Some RA patients show collagenase 3 mRNA expression in the synovial membrane, which correlates with elevated levels of systemic markers of inflammation in these patients.	10403281
Chronic inflammatory disorder	Altered Intercellular Communication	The stability of established memory T helper (Th)1/Th2 cells in chronic inflammatory diseases is not clear, and a shift of the cytokine balance could control chronic inflammation.	10404044
Inflammation, Tumor necrosis, Rheumatoid Factor	Altered Intercellular Communication	To explore the role of CTLA-4 molecule in the inflammation of rheumatoid joints, CTLA-4 was blocked with anti-CTLA-4 antibody to assess its effects on the production of tumour necrosis factor alpha and interleukin 1beta in synovial fluid mononuclear cell culture.	10404054
Rheumatic Fever	Altered Intercellular Communication	The data suggest that the expression of CTLA-4 plays a down-regulatory role in rheumatoid articular inflammation.	10404054
Adenocarcinoma, Inflammation, Carditis, Atrophic	Altered Intercellular Communication	Carriage of cagA(+) strains was present in 34% of patients with carditis and significantly associated with increased frequency and severity of cardia inflammation, IM, and atrophy but not with adenocarcinoma.	10404065
Symptoms, Primary malignant neoplasm, Asthma, Airway structure	Altered Intercellular Communication	Chemotherapy reduces the prevalence of asthma symptoms in children with cancer: implications for the role of airway inflammation in asthma.	10404448
Airway structure, Symptoms	Altered Intercellular Communication	Airway inflammation is an important determinant of asthma symptoms.	10404448
Airway structure, Asthma	Altered Intercellular Communication	Prospective study of the airways of this group of patients promises to provide insights into the relationships between airway hyperreactivity, airway inflammation and asthma.	10404448
Brain Neoplasms, Pituitary Adenoma	Altered Intercellular Communication	Therefore, detection of PROP1 might be a useful indicator for differentiating pituitary adenomas, regardless of their hormonal phenotypes, from other brain tumors.	10404841
Inflammation, Fibrosis Assessment, Recurrent lower respiratory tract infection	Altered Intercellular Communication	Cystic fibrosis (CF) is associated with chronic lung infection, inflammation, and elevated indices of oxidative stress.	10405967
Inflammation, Hypertension, CTCAE, Malignant Neoplasms	Altered Intercellular Communication	There was no evidence of malignancy, portal hypertension, or inflammation in any organ other than the bowel.	10406275
Autoimmune necrotizing myopathy, Autoimmune Diseases, Unknown (origin) (qualifier value), Scleritis, Infectious Arteritis, Rheumatoid scleritis	Altered Intercellular Communication	On the basis of their histologic features, rheumatoid scleritis and related systemic autoimmune-mediated necrotizing scleral inflammations could be differentiated from either idiopathic or infectious scleritis; however, the histologic features of rheumatoid scleritis were similar to those of necrotizing scleritis associated with other systemic autoimmune diseases.	10406616
Acute intermittent porphyria	Altered Intercellular Communication	Premenstrual attacks of acute intermittent porphyria: hormonal and metabolic aspects - a case report.	10407223
Inflammation	Altered Intercellular Communication	An increased turnover of cartilage matrix in joint inflammation might explain this correlation.	10408068
Inflammation, Weight decreased, Carcinoma of lung	Altered Intercellular Communication	Weight loss and low body cell mass in males with lung cancer: relationship with systemic inflammation, acute-phase response, resting energy expenditure, and catabolic and anabolic hormones.	10409477
Inflammation, Weight decreased, Carcinoma of lung	Altered Intercellular Communication	We conclude that, in human lung cancer, weight loss and the presence of a low BCM are associated with systemic inflammation, an increased acute-phase response and decreased levels of IGF-I.	10409477
Inflammation, Weight decreased, Carcinoma of lung	Altered Intercellular Communication	Weight loss and low body cell mass in males with lung cancer: relationship with systemic inflammation, acute-phase response, resting energy expenditure, and catabolic and anabolic hormones.	10409477
Inflammation, Neoplasms	Altered Intercellular Communication	The resected specimen had severe inflammation without any evidence of residual tumor.	10410317
Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	The beta2 integrin CD11b plays a central role in inflammation and the systemic inflammatory response syndrome (SIRS).	10410993
Cystitis	Altered Intercellular Communication	Nitric oxide: a useful gas in the detection of lower urinary tract inflammation.	10411031
Inflammation, Pain Distress Question, Pyloric Stenosis, Interstitial Cystitis, Nonneurogenic neurogenic bladder dysfunction, Inflammatory disorder, Nocturia	Altered Intercellular Communication	We determine whether luminal nitric oxide can be used as a marker to differentiate inflammation, that is interstitial cystitis, from urgency, frequency, nocturia and pain due to noninflammatory disorders, such as outflow obstruction and neurogenic dysfunction.	10411031
Inflammation, Pyloric Stenosis, Neurogenic Urinary Bladder	Altered Intercellular Communication	Measurement of nitric oxide in air from the bladder is a simple, safe and fast method to differentiate urgency due to inflammation from neurogenic disorders or outflow obstruction.	10411031
Inflammation, Crohn Disease, Malignant lymphoma - lymphoplasmacytic	Altered Intercellular Communication	These results suggest that chronic inflammation in Crohn's disease contributes to the simultaneous development of biclonal lymphoplasmacytic immunocytoma of the small intestine.	10411357
Inflammation, Refractory anemias, Synovial joint structure, Rheumatoid Arthritis, Hyperplasia	Altered Intercellular Communication	Rheumatoid arthritis (RA) is characterized by a chronic inflammation of the synovial joints resulting from hyperplasia of synovial fibroblasts and infiltration of lymphocytes, macrophages, and plasma cells, all of which manifest signs of activation.	10411542
Refractory anemias, Inflammation, Destruction (action)	Altered Intercellular Communication	Therefore, inhibiting Src activity can be a good therapeutic strategy to prevent joint inflammation and destruction in RA.	10411542
Inflammation, Arthritis, bone destruction	Altered Intercellular Communication	Furthermore, local injection of the virus into rat ankle joints with adjuvant arthritis not only ameliorated inflammation but suppressed bone destruction.	10411542
Abscess, Inflammation, Pouchitis	Altered Intercellular Communication	Specific complications concerned mainly the pouch-anal anastomosis (fistulas, abscesses, consecutive stenosis) and inflammation of the pouch mucosa (pouchitis).	10412597
Inflammation, Fibrosis Assessment, Granulomatous, Lymphadenitis, atherosclerotic	Altered Intercellular Communication	Histology showed that a granulomatous reaction against some components of the atherosclerotic plaques resulting in an auto-allergic response to this component could initiate the inflammatory process thus resulting in a progressive adventitial and peri-adventitial fibrosis with inflammation, lymphadenitis and lymphatic dilatation.	10412930
Intraocular inflammation	Altered Intercellular Communication	After surgery, neovascularization and intraocular inflammation decreased, and the corrected visual acuity in the right eye improved to 20/50.	10413255
Abscess, Primary malignant neoplasm, Inflammation, Pancreas	Altered Intercellular Communication	The cytological results of 45 pancreatic lesions showed cancer in 19 and chronic inflammation in 21, two abscesses and three benign cysts.	10413842
Cataract, Inflammation, Glaucoma, CTCAE, Glaucoma, Primary Open Angle	Altered Intercellular Communication	PXEG has an higher incidence of typical problems of phacoemulsification, a temporary increase of IOP and prolonged inflammation after combined cataract and glaucoma surgery than POAG, but there is a similar risk compared to a single procedure.	10414120
Inflammation, Lymphoma	Altered Intercellular Communication	Considering the rarity of these two entities in the vagina, it is unlikely that the association in this case is coincidental, raising the possibilities of an unusual reaction to the presence of lymphoma or a common pathogenesis such as underlying chronic inflammation.	10414509
Inflammation, Hemorrhagic necrosis	Altered Intercellular Communication	Each consistently showed hemorrhagic necrosis and tissue devitalization without significant inflammation.	10414729
Inflammation, Fibrosis Assessment, Squamous metaplasia	Altered Intercellular Communication	Each showed periurethral fibrosis, nonspecific chronic inflammation, and squamous metaplasia of the urothelium.	10414729
Airway structure, Eosinophilic disorder	Altered Intercellular Communication	Glucocorticosteroids inhibit mRNA expression for eotaxin, eotaxin-2, and monocyte-chemotactic protein-4 in human airway inflammation with eosinophilia.	10415058
Myocarditis	Altered Intercellular Communication	Results suggest that apoptosis may play some role in the repairing process of myocardial inflammation.	10415552
Inflammation	Altered Intercellular Communication	Fifteen (31 %) of 49 patients and none of the 10 control patients exhibited abnormalities of the glandular ducts compatible with chronic inflammation of the salivary ducts (p = 0.039).	10416689
Inflammation, Xanthoma	Altered Intercellular Communication	Inflammation and xanthoma cells were absent and occasional capillaries were present.	10417526
Injury of central nervous system, Inflammation	Altered Intercellular Communication	Many recent studies have emphasized the deleterious role of inflammation in CNS injury.	10417811
Inflammation, Short Bowel Syndrome	Altered Intercellular Communication	The combination of chronic inflammation and the short bowel syndrome appears to be necessary for the development of ESLD with prolonged home TPN.	10418589
Inflammation, Dysplasia	Altered Intercellular Communication	To learn more about the molecular mechanism of the alteration of the mucus layer, the expression of the main intestinal mucin, MUC2, was investigated in relation to inflammation and dysplasia.	10419600
Inflammation	Altered Intercellular Communication	This alteration occurred in the inactive phase of inflammation and persisted in the active phase of the disease.	10419600
Inflammation, Dysplasia	Altered Intercellular Communication	The IRS values did not correlate with the grade of inflammation or dysplasia.	10419600
Non-infective Inflammatory Bowel Disease	Altered Intercellular Communication	However, the dominant clinical symptom has been characterized by a non-infectious chronic inflammatory condition with infiltration of inflammatory cells in the synovial tissue or synovial fluid, especially in the early stage of the disease.	10419780
Intraocular inflammation	Altered Intercellular Communication	The results confirmed the role of IL-6 in intraocular inflammation and gave new information regarding the presence of its sR in normal and inflamed eyes.	10420202
Inflammation, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	Hepatocellular carcinoma (HCC) mainly arises from the liver with chronic inflammation.	10421648
Inflammation, FAM126A gene	Altered Intercellular Communication	We studied 20 HCC and surrounding noncancerous liver tissues (SL) obtained by surgical resection, and 10 laparoscopically obtained needle biopsy specimens of the liver with chronic inflammation including no overt HCC (CI).	10421648
Inflammation, CD55 gene	Altered Intercellular Communication	To compare TC in the liver with respect to chronic inflammation, the value was divided by TC in peripheral blood leukocytes (PBL) from the same donor.	10421648
Inflammation, FAM126A gene	Altered Intercellular Communication	These observations suggest that RTC value in liver tissues may digitally indicate a replicative history of hepatocytes under chronic inflammation, and a risk of HCC development.	10421648
Acute myocardial infarction, Inflammation, Cardiopulmonary Arrest, Abdominal Pain	Altered Intercellular Communication	We discuss a case of a 68 years old man with an acute myocardial infarction and a cardiopulmonary arrest that 3 days after his admission developed a continuous abdominal pain and findings of peritoneal inflammation.	10422300
Pneumonitis	Altered Intercellular Communication	Evidence suggests that lymphocyte GSH reflects lung GSH concentrations, and so could potentially serve as a peripheral marker of lung inflammation.	10424526
Pneumonitis	Altered Intercellular Communication	Peripheral blood lymphocyte GSH concentration may potentially serve as a convenient marker of lung inflammation.	10424526
Gallstone acute pancreatitis, Interstitial inflammation	Altered Intercellular Communication	Bile of six patients with acute gallstone pancreatitis (29%) induced interstitial inflammation in the rabbit pancreas.	10425414
Gallstone pancreatitis, Inflammation	Altered Intercellular Communication	In most patients with gallstone pancreatitis, bile is neither infected nor harmful to the pancreas, and its flow into the gland is unlikely to be the cause of inflammation.	10425414
Necrotizing granulomatous inflammation, Rupture, Rathke Cleft Cysts	Altered Intercellular Communication	Histological examination showed foreign body type xanthogranulomatous inflammation in the neurohypophysis which might have been caused by rupture of a Rathke's cleft cyst.	10426586
Vasodilation, Edematous skin, Vasculitis	Altered Intercellular Communication	The histologic features included dermal edema, vascular dilatation, and small vessel inflammation with a dense polymorphous inflammatory infiltrate rich in eosinophils.	10426914
Inflammation, Fibrosis Assessment, Degenerative disorder of cartilage	Altered Intercellular Communication	Perichondrial inflammation and cartilage degeneration with fibrosis were characteristically observed.	10426914
Inflammation	Altered Intercellular Communication	Metallic debris due to micromotion especially around the rod and the crosslink connections caused this inflammation.	10427800
Pain Distress Question, Inflammatory abnormality of the eye	Altered Intercellular Communication	Our success criteria was an IOP less than 22 mm Hg with the same visual acuity and without pain and ocular inflammation.	10427919
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	In this preliminary study, active inflammation of the left colon in patients with Crohn's disease or with ulcerative colitis was associated with a substantial increase in inferior mesenteric artery flow that could be seen on Doppler sonography.	10430141
Inflammation, Primary malignant neoplasm, Biliary calculi	Altered Intercellular Communication	However, it is difficult to know cancer depth exactly before or during operation, especially when combined with inflammation due to gallstones.	10430293
Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	MALT lymphomas may rarely occur in organs where lymphoid tissue is sparse, especially following inflammatory conditions.	10430312
Inflammation, Infection, Necrosis	Altered Intercellular Communication	NSTIs, which are characterized by rapidly progressing inflammation and necrosis of soft tissue, comprise a spectrum of disease ranging from necrosis of the skin to life-threatening infections.	10430326
Inflammation, Tuberculosis	Altered Intercellular Communication	However, the histopathology of the pancreas revealed caseating granulomatous inflammation of possible tuberculous etiology, although special staining and culture of these tissues gave negative results.	10430386
Inflammation	Altered Intercellular Communication	The inflammation, its activity, H. pylori and other mucosal alterations were investigated semi-quantitatively and assessed according to the Sydney system.	10430396
Inflammation	Altered Intercellular Communication	In the cardia, corpus and antrum, significant decrease in chronic inflammation, and H. pylori activity (p<0.001) was found.	10430396
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Eradication therapy was closely associated with a significant decrease of inflammation activity and H. pylori infection.	10430396
Stomach Diseases, Inflammation, Hemorrhage, Mucous Membrane, Intestinal metaplasia	Altered Intercellular Communication	Chronic inflammation, mucosal atrophy and intestinal metaplasia persisted, even though their intensity was decreased, and signs of chemical gastropathy with hemorrhages in the esophageal papillae were found.	10430396
Malignant neoplasm of urinary bladder	Altered Intercellular Communication	It has an important role in the diagnosis of residual disease after TURB and in the follow-up evaluation of bladder cancer patients, since its dosage is not influenced by inflammatory conditions of the mucosa.	10431409
Inflammation, Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	Angiogenesis is an important part of normal and pathological processes, including tumour growth, metastasis, inflammation and wound healing.	10431840
Granulomatous inflammation, Destruction of tissue	Altered Intercellular Communication	Corticosteroids may diminish granulomatous inflammation, thereby preventing further tissue destruction, and there is evidence that they also reduce ova deposition.	10432054
Hyperthyroidism	Altered Intercellular Communication	Inflammation of the cardiac conduction system in a case of hyperthyroidism.	10433039
Hyperthyroidism, Interstitial inflammation	Altered Intercellular Communication	The autopsy findings showed an interstitial inflammation of the AV-node, the His-bundle and its branches which can correlate with typical ECG changes in hyperthyroidism.	10433039
Inflammation, Squamous cell carcinoma, Dysplasia	Altered Intercellular Communication	Among the 13 positive sites suggested by LIF imaging, 5 were confirmed by histopathology as squamous cell carcinoma, 4 as dysplasia, 2 as inflammation, and 2 as normal.	10435932
Airway structure, Bronchitis	Altered Intercellular Communication	The ideal antimicrobial agent for the management of acute exacerbations of chronic bronchitis (AECB) should have good activity against the common bacterial pathogens associated with these exacerbations (non-typable Haemophilus influenzae, Moraxella catarrhalis and pneumococci); it should be resistant to bacterial betalactamases; penetrate well into pulmonary tissues and secretions; kill bacteria without inducing excessive airway inflammation; be easy to take (given once or twice a day) in order to ensure high patient compliance, and be cost-effective.	10436551
Inflammatory abnormality of the eye	Altered Intercellular Communication	A two points or more reduction in the ocular inflammation score was observed in 52% of patients.	10436711
Cerebrovascular Disorders	Altered Intercellular Communication	Vasoactive intestinal peptide (VIP) appears to play an important role as a neurotransmitter or neuromediater in ischemic cerebrovascular diseases (ICVD).	10437215
Inflammation	Altered Intercellular Communication	Chemokines play a key role in modulating leukocyte functions at sites of inflammation.	10437780
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	Higher levels of SF ferritin, as well as SF CRP and SF A-SAA, seem to reflect greater degrees of joints inflammation in RA and OA.	10439120
Perforation (observation), Rectal Ulcer, CTCAE, Lupus Erythematosus, Systemic, Lupus Erythematosus, Pelvic Inflammatory Disease	Altered Intercellular Communication	A 41-year-old man with systemic lupus erythematosus (SLE) who developed pelvic inflammation due to perforation of a giant rectal ulcer is described.	10440500
Inflammation, Carcinoma	Altered Intercellular Communication	Many studies have demonstrated in animal experiments that persistent inflammation may accelerate the development of carcinoma.	10440686
Refractory anemias, Pain Distress Question, Immobile, Inflammation	Altered Intercellular Communication	Interference of RF reactivity, especially in RA patients, may alleviate the pain and immobility resulting from chronic inflammation of the joints.	10440996
Inflammatory abnormality of the eye	Altered Intercellular Communication	Amniotic membrane transplantation markedly reduced ocular inflammation in all patients.	10442895
Inflammation, Cellulitis	Altered Intercellular Communication	Cellulitis is an inflammation of subcutaneous tissue in which infective, generally bacterial cause is proven or assumed.	10443081
Cystitis	Altered Intercellular Communication	Measurement of luminal nitric oxide in bladder inflammation using a silicon balloon catheter: a novel minimally invasive method.	10443722
Interstitial Cystitis, Communicable Diseases, Cystitis	Altered Intercellular Communication	Elevated NO levels were detected in the urinary bladder in patients with bladder inflammation due to infection or interstitial cystitis.	10443722
Inflammation	Altered Intercellular Communication	Emerging evidence for inflammation in conditions frequently affecting older adults: report of a symposium.	10443865
Inflammation, Blepharoptosis	Altered Intercellular Communication	Ptosis can result from rigid gas permeable (RGP) contact lens wear due to contact lens migration, inflammation, and undetermined causes.	10444052
Tumor necrosis, Helicobacter Pylori-Associated Gastric Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	Increased production of proinflammatory cytokines, including tumour necrosis factor-alpha (TNF-alpha), IL-1beta, IL-6 and IL-8, has been demonstrated in Helicobacter pylori-associated gastric mucosal inflammation.	10444264
Inflammation, Gastritis	Altered Intercellular Communication	Gastritis was graded for chronic inflammation or acute inflammatory activity, respectively, according to the Sydney system.	10444264
Inflammation, Residual volume	Altered Intercellular Communication	These findings suggest that respiratory submucosal gland cells play an important role in the initial stages of inflammation and provide useful insights into the pathogenesis of RV infection.	10444531
Cessation of life, Inflammation, Infectious Lung Disorder	Altered Intercellular Communication	Compared with patients free of inflammation, these patients had more diseases per individual (more than two diseases: 70% versus 50%, p < 0.01), lower albumin, prealbumin and cholesterol levels and, when in hospital, more frequent pulmonary infections (31 vs 12%, p < 0.05) and higher death rate (20% vs 5%, p < 0.05).	10445088
Inflammation, Infection	Altered Intercellular Communication	CRP increased with age (R = 0.23, p < 0.01) independently of inflammation and was neither correlated to infections nor to mortality unlike the orosomucoid.	10445088
Inflammation	Altered Intercellular Communication	These data are in agreement with the mechanisms of transcriptional regulation of certain genes (NFkappaB, IL6, orosomucoid) involved in inflammation and their modification through ageing.	10445088
Cataract, Inflammation	Altered Intercellular Communication	To compare the course of postoperative inflammation after small incision cataract surgery with implantation of 4 types of foldable intraocular lenses (IOLs).	10445198
Acute inflammation	Altered Intercellular Communication	Comparison of postoperative flare values after implantation of 4 foldable IOLs showed no clinically relevant differences in the course of postoperative inflammation.	10445198
Communicable Diseases, Inflammation, Necrosis	Altered Intercellular Communication	Ceruloplasmin (Cp) protein binds 90% of the copper in plasma and it is one of the positive APhPs, and its concentration increases in infection, inflammation or necrosis.	10445222
Granulomatous inflammation, Sarcoidosis, Pulmonary	Altered Intercellular Communication	Apoptosis in the course of granulomatous inflammation in pulmonary sarcoidosis.	10445608
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	Therefore, it was hypothesized that the Fas/FasL pathway and apoptosis may be associated with the course of granulomatous inflammation in sarcoidosis.	10445608
Granulomatous inflammation	Altered Intercellular Communication	Apoptosis in epithelioid histiocytes and inflammatory cells seems to participate in the course of granulomatous inflammation.	10445608
Granulomatous inflammation, Sarcoidosis, Pulmonary	Altered Intercellular Communication	Further studies are needed to determine the role of Fas, FasL and other regulatory factors in apoptosis in the granulomatous inflammation in pulmonary sarcoidosis.	10445608
Inflammation, Asthma	Altered Intercellular Communication	Exhaled nitric oxide and sputum eosinophil markers of inflammation in asthmatic children.	10445616
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide and eosinophil sputum markers are considered noninvasive ways in which to evaluate airway inflammation in asthma.	10445616
Airway structure, Asthma	Altered Intercellular Communication	In conclusion, exhaled NO and sputum eosinophil counts are concordant in evaluating the degree of airway inflammation in patients with mild-to-moderate asthma.	10445616
Inflammatory Bowel Diseases, Inflammation, Intestinal Diseases	Altered Intercellular Communication	Forty four per cent of patients receiving these drugs had NSAID induced enteropathy when assessed by this technique; 20% of these had comparable levels of inflammation to that previously reported in patients with inflammatory bowel disease.	10446103
Inflammation, Data types - Address	Altered Intercellular Communication	In addition, increasing data claim the importance of chronic inflammation in the pathogenesis of AD.	10446805
Pituitary hormone deficiencies, Adrenal Androgen Deficiency	Altered Intercellular Communication	Arguments that pituitary hormone deficiency might increase the hemodynamic consequences of adrenal deficiency are discussed.	10447549
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	We report the sporadic occurrence in autoimmune diseases of such autoantibodies to granulocyte-macrophage colony-stimulating factor (GM-CSF), a cytokine involved in inflammation and the regulation of proliferation, differentiation and function of granulocytic and monocytic cell lineages.	10447777
Neoplasms	Altered Intercellular Communication	[Detection of human papillomavirus types in tumors and inflammations of the eye].	10448632
Neoplasms	Altered Intercellular Communication	The DNA techniques used in this study represent important methods for the detection of HPV types and allow an association of HPV types with defined tumours and inflammations of the eye.	10448632
Inflammation, Ischemic stroke, Coronary heart disease	Altered Intercellular Communication	Several markers of hemostatic function and inflammation have been associated with increased risk of coronary heart disease, but prospective evidence for their role in ischemic stroke is scant.	10449696
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	This study offers modest support for the hypothesis that some markers of hemostatic function and inflammation can identify groups of middle-aged adults at increased risk of stroke.	10449696
Inflammation, Malignant Neoplasms, gallbladder wall thickening	Altered Intercellular Communication	Four of these cancers (0.22%) were in 1,831 gallbladders with normal walls, two (1.0%) were in 186 with thicker walls, and two (1.8%) were in 109 patients in whom conversion was necessary because of extensive inflammation and thickening of gallbladder wall.	10449848
Inflammation, Tuberculosis	Altered Intercellular Communication	The most common diagnosis was reactive change/nonspecific inflammation, constituting 33.4%; tuberculosis and metastatic lesions made up 25.	10450098
Mixed Salivary Gland Tumor, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	A cytologic diagnosis of malignancy was established in 13 (50%) cases, 2 (7.7%) were suspicious, and 11 (42.3%) were negative for malignancy (10 pleomorphic adenomas, 1 inflammation).	10450099
Inflammation	Altered Intercellular Communication	However, given its function as an acute-phase protein, the question has been raised whether an elevated caeruloplasmin level is not merely an indicator of inflammation.	10450332
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	In the current study, we investigated whether serum caeruloplasmin was associated with subsequent myocardial infarction, taking into account indices of inflammation.	10450332
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	This suggests that a substantial part of the observed association between serum caeruloplasmin and CHD may be attributed to inflammation processes rather than to the pro-oxidant activity of caeruloplasmin.	10450332
Inflammation, Disease remission	Altered Intercellular Communication	On later follow-up images, the structure of the articular cartilage remained unaltered in all but 3 patients, who had new, superficial erosions most likely attributed to an active disease with persistence of inflammation.	10450678
Gingivitis, Dental Plaque	Altered Intercellular Communication	The influence of smoking was independent of age, plaque and gingival inflammation.	10450815
Inflammation	Altered Intercellular Communication	Histologically, it was degenerative disc material without active inflammation.	10451046
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	To investigate lipid profiles in patients with untreated active rheumatoid arthritis (RA) and to assess the relationship of the inflammatory condition of RA with lipid profiles.	10451065
Refractory anemias	Altered Intercellular Communication	The inflammatory condition of RA may affect the metabolism of HDL-cholesterol and apo A1.	10451065
Inflammation, Hemorrhage	Altered Intercellular Communication	Haemorrhage and inflammation were the most common presenting symptoms.	10452262
Diverticular disease of colon, Inflammation	Altered Intercellular Communication	All histopathological signs of inflammation were found in those with symptomatic diverticula.	10452262
Benign prostatic hypertrophy	Altered Intercellular Communication	Prostate glands with established benign prostatic hyperplasia may be less responsive to these hormonal changes.	10452601
Inflammation	Altered Intercellular Communication	The density of H. pylori was significantly correlated with polymorphonuclear neutrophil activity and chronic inflammation.	10452678
Complication Aspects, Sinusitis	Altered Intercellular Communication	[Orbital and intracranial complications of paranasal sinus inflammation].	10453231
Interstitial inflammation	Altered Intercellular Communication	Renal biopsy revealed an interstitial inflammation, principally of plasma cells with some lymphocytes and eosinophils.	10454785
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histologically, LSE had the thickest epidermis (P = .02), PUF had the greatest degree of fibrosis (P = .02), and autograft had the least degree of increased inflammation (P = .004) and vascularity (P = .01).	10456339
Airway structure, Asthma	Altered Intercellular Communication	Nitric oxide metabolites in induced sputum: a marker of airway inflammation in asthmatic subjects.	10457119
allergic inflammation	Altered Intercellular Communication	The role of nitric oxide (NO) needs to be further clarified in allergic inflammation.	10457119
Airway structure	Altered Intercellular Communication	Measurement of NO metabolites in induced sputum may be used for monitoring the degree of airway inflammation in asthmatics.	10457119
Inflammation, Acute Cholecystitis	Altered Intercellular Communication	A total of 152 cases of laparoscopic cholecystectomy for acute cholecystitis (evidence of acute inflammation clinically and pathologically) were identified.	10457324
Inflammation, Neoplasms	Altered Intercellular Communication	In contrast, in regions adjacent to the tumor, which showed chronic inflammation, there was always high expression in the acinar and inflammatory cells, explaining the increased Bak levels found in the tumor samples by means of Northern blot analysis.	10457328
Cessation of life, Chronic inflammation	Altered Intercellular Communication	In situ analysis using the terminal deoxynucleotidyl transferase method further showed that there was extensive cell death in the peritumorous areas with chronic inflammation.	10457328
Inflammation, Pancreatic carcinoma, Neoplasms	Altered Intercellular Communication	Taken together, these results suggest that in pancreatic cancer Bak expression and programmed cell death are present in cells that are localized in regions of chronic inflammation surrounding the pancreatic cancer cells but not in the tumor cells themselves, a situation that may facilitate tumor growth and spread.	10457328
Inflammation	Altered Intercellular Communication	The inflammation did not respond to an extensive course of medical management, and the patient developed complications associated with both the disease process and his medical therapy.	10458138
Inflammation, Traumatic injury	Altered Intercellular Communication	This disruption may occur in response to trauma, focal inflammation, or other localized stimuli.	10458294
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Based on two pathological parameters of hepatic fibrosis and inflammation, the cases were divided into five groups; group A (non-inflammatory group without significant fibrosis; 11 cases), group B (inflammatory group without significant fibrosis; 9 cases), group C (non-inflammatory group with significant fibrosis; 1 case), group D (inflammatory group with significant fibrosis; 11 cases) and group E (undetermined inflammatory index; 5 cases).	10459633
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Haloperidol treatment seemed to alleviate inflammation in rheumatoid arthritis.	10460194
Crohn Disease, Ulcerative Colitis, Colitis	Altered Intercellular Communication	Overexpression of CD44v6 in colon crypt epithelial cells has been suggested to have diagnostic potential in differentiating ulcerative colitis from other forms of colon inflammation, including Crohn's disease.	10460659
Inflammation, Bacterial endophthalmitis	Altered Intercellular Communication	Intravitreal dexamethasone helps in early reduction of inflammation in exogenous bacterial endophthalmitis, but has no independent influence on the visual outcome.	10460774
Inflammation, Cholelithiasis	Altered Intercellular Communication	There were no significant differences between the AUPBD-present group and the AUPBD-absent group in the incidence of gallstone disease, while the incidence of acute inflammation was 93% (26/28) in the AUPBD-absent group (p < 0.01).	10461418
Inflammation, Atherosclerosis, Cerebrovascular accident	Altered Intercellular Communication	could be one of the markers for systemic inflammation and be important in the patogenesis of atherosclerosis and stroke.	10463245
Cataract, Inflammation, Traumatic injury	Altered Intercellular Communication	Such absorption is known in juveniles and in hypermature cataract, but is rare in adults in the absence of injury or inflammation.	10463428
Ischemia	Altered Intercellular Communication	Previously, a prominent COX-2 upregulation was described in neurons few hours or days after ischemia but little is known about COX-2 expression in non-neuronal cells participating in post-ischemic inflammation.	10464424
Inflammation, Fever, CTCAE, Arthralgia, Myalgia, Photosensitivity of skin, Ulcer, Fatigue	Altered Intercellular Communication	Patients in Group A suffered from more severe joint pain and inflammation, muscle pain, photosensitivity, mouth ulcers, fever and fatigue.	10464560
Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	Lung biopsies in this group were characterized by varying proportions of chronic interstitial inflammation and fibrosis which was temporarily uniform.	10464862
Airway structure, Asthma, airway disease	Altered Intercellular Communication	Induced sputum differential cell counts have been advocated as a method of non-invasively assessing airway inflammation in asthma and other airway diseases.	10464902
Inflammation	Altered Intercellular Communication	Since the content of neuropeptides seems to be altered in chronic inflammation, we investigated possible changes in peptidergic innervation for substance P (SP), vasoactive intestinal peptide (VIP), and growth-associated protein-43 (GAP-43).	10465170
Gastroesophageal reflux disease, Inflammation, Symptoms, Colonization	Altered Intercellular Communication	Patients with nonerosive GERD often show dyspeptic symptoms and higher H. pylori colonization and inflammation grades in the proximal stomach.	10466875
Inflammation, Myocardial Ischemia, Atherosclerosis	Altered Intercellular Communication	Increased expression of the CD11b/CD18 antigen on the surface of peripheral white blood cells in patients with ischemic heart disease: further evidence for smoldering inflammation in patients with atherosclerosis.	10467208
Inflammation, Calcinosis	Altered Intercellular Communication	An alternative procedure is pericystectomy and drainage with a "planned" reoperation with a bloodless, due to intervening inflammation, chiseling of the calcification.	10468117
Inflammation, Morning stiffness - joint	Altered Intercellular Communication	Patients with a poor response to rHuEPO showed greater clinical symptoms (morning stiffness, the number of swollen joints, Ritchie index) and higher laboratory inflammation parameters (ESR, CRP, platelets, IL-6, TNFalpha, IL-1beta) than patients with a good response to rHuEPO.	10468168
Inflammation	Altered Intercellular Communication	The poor-response group showed a significant decrease in the progression of inflammation compared with the good-response group.	10468168
Inflammation	Altered Intercellular Communication	However, it is important to determine this approach under good control of inflammation.	10468168
Tumor necrosis, Asthma, Inflammation	Altered Intercellular Communication	Tumour necrosis factor (TNF) is a pivotal cytokine in the inflammation underlying asthma.	10469028
Cataract, Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	To identify the cellular immune processes underlying intra-ocular inflammation, aqueous humour was obtained at cataract surgery from 22 patients with clinically inactive uveitis and 24 patients with age-related cataract.	10469047
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	The presence of clonally-related B-lymphocyte aggregates within synovial lining tisue of rheumatoid arthritis (RA) patients suggests a germinal centre-like reaction, which may hold implications for disease pathogenesis and the causes of chronic inflammation.	10469243
Communicable Diseases, Inflammation	Altered Intercellular Communication	Whether duration of infection and inflammation pattern determine the outcome of the neoplastic process is not known.	10470530
Inflammatory Breast Carcinoma	Altered Intercellular Communication	In diffuse type carcinomas inflammation was either absent or mild.	10470530
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	Our study shows that the (pre)atrophic phases of inflammation are associated with gastric carcinomas.	10470530
Chronicity, Inflammation, Lymphoma cells	Altered Intercellular Communication	In contrast the active phase of inflammation, characterized by severe activity as well as severe chronicity, is found next to marginal zone cell lymphoma.	10470530
Inflammation, Gastritis, Nodularity, Atrophic	Altered Intercellular Communication	Multivariate analysis has strictly correlated age with all abnormal endoscopic features, metaplasia with endoscopic atrophy, and chronic inflammation (gastritis) with nodularity.	10470592
Multiple Sclerosis, MS gene	Altered Intercellular Communication	Inflammation of multiple sclerosis (MS) brain and spinal cord tissue consists of macrophages, T lymphocytes and cytokines as well as B lymphocytes and immunoglobulins (IgGs).	10473981
Inflammation, Prostate carcinoma	Altered Intercellular Communication	High-grade inflammation in prostate cancer as a prognostic factor for biochemical recurrence after radical prostatectomy.	10475356
Prostate carcinoma, prostatitis	Altered Intercellular Communication	To assess the prognostic value of prostatic stromal inflammation in surgically treated localized prostate carcinoma for biochemical recurrence-free survival.	10475356
Inflammation	Altered Intercellular Communication	Inflammation was graded as high-grade inflammation if confluence of inflammatory cell infiltrate and/or glandular epithelium disruption associated with interstitial inflammatory infiltrate were present and as low-grade inflammation otherwise.	10475356
Intracapsular cataract extraction, Acute inflammation	Altered Intercellular Communication	To quantitatively compare postoperative inflammation after extracapsular cataract extraction (ECCE) with that after phacoemulsification in an Asian population.	10476515
Communicable Diseases, Inflammation	Altered Intercellular Communication	Healing was uneventful; no inflammation, infection, or soft tissue dehiscence was observed.	10476892
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Lymph nodes were enlarged and often fragmented due to capsular fibrosis and chronic inflammation, with focal obliteration of the subcapsular sinus.	10478137
Inflammation, Ear Inflammation, Otitis Media with Effusion	Altered Intercellular Communication	We indwelt a tympanic membrane ventilation tube (hereinafter referred to as tube) for treatment of otitis media with effusion (OME) in child patients aged 3-13 years and investigated the following points: i) relationship between the severity of inflammation of the lamina propria of middle ear mucosal specimens (hereinafter referred to as lamina propria) collected at the time of tube indwelling and the degree of growth of the pneumatic space; and ii) changes in the pneumatic space associated with treatment by tube indwelling, which was studied by comparing the above-described mucosal severity with the pneumatic space area of 2 years after tube indwelling, and with increase in the pneumatic space volume measured periodically after tube indwelling.	10478596
Inflammation	Altered Intercellular Communication	We confirmed that the severity of inflammation of the lamina propria is deeply involved in the growth and repneumatization of the pneumatic cells.	10478596
Inflammation, Bone Marrow Diseases, Anemia, idarubicin, Chronic disease	Altered Intercellular Communication	27 patients had primary bone marrow disease, 25 patients had absent bone marrow iron stores accompanied by inflammation, 17 patients had anaemia of chronic disease (ACD) and 8 patients had uncomplicated iron deficiency anaemia (IDA).	10480289
Inflammation, Pleurisy	Altered Intercellular Communication	These findings suggested that the symptoms of general inflammation were induced by local pleural inflammation.	10481458
Inflammation	Altered Intercellular Communication	A panel of monoclonal antibodies to characterize epidermal proliferation, differentiation and inflammation were selected.	10482007
Inflammation	Altered Intercellular Communication	We found no evidence of consistently increased anterior segment inflammation or intraocular pressure after surgery when compared with preoperative levels for this group of patients.	10482090
Cataract, Intraocular Route of Drug Administration, Inflammation, Uveitis	Altered Intercellular Communication	To report a series of patients with uveitis and cataract who had undergone cataract extraction with posterior chamber intraocular lens implantation and who subsequently had the intraocular lens removed because of progressive intraocular damage from inflammation.	10482091
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Mucosal inflammation in ulcerative colitis (UC) is presumed to be regulated by Th2-like cytokines.	10484006
Inflammation	Altered Intercellular Communication	The positive rate of IL-2, interferon (IFN)-gamma, and IL-15 expression showed no difference among the groups divided by clinical, endoscopic, and histological grade of inflammation.	10484006
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In contrast, Th1-like cytokines and IL-15 bear no definite relation to local inflammation of UC.	10484006
Inflammation, Decreased vascular flow, Ischemia	Altered Intercellular Communication	Arterial wall inflammation results in reduction of blood flow and subsequent ischemia.	10485174
Eosinophilic disorder, Inflammation, Necrosis	Altered Intercellular Communication	Cytoplasmic eosinophilia, single cell necrosis, and occasionally subepithelial chronic inflammation were also seen.	10485547
Gastroesophageal reflux disease, Carditis	Altered Intercellular Communication	Inflammation of the gastro-oesophageal junction (carditis) in patients with symptomatic gastro-oesophageal reflux disease: a prospective study.	10486352
Inflammation	Altered Intercellular Communication	According to the Sydney grading there was significant improvement in corpus inflammation after eradication.	10486354
Symptoms, Inflammation, Lymphocytic gastritis	Altered Intercellular Communication	H pylori eradication treatment in patients with lymphocytic gastritis causes significant improvement in the gastric IEL infiltrate, corpus inflammation, and dyspeptic symptoms.	10486354
Inflammation, Leprosy	Altered Intercellular Communication	The AFB (+)-rate appears likely to be higher in non-ulcering skin lesions with minor inflammation or in lesions with leprosy reaction than typical skin lesions such as papules, nodules, and infiltrated punched out skin lesions.	10487001
Inflammation, Helicobacter pylori	Altered Intercellular Communication	A biopsy specimen disclosed a benign gastric mucosa with moderate inflammation within the lamina propria, and organisms consistent with Helicobacter pylori.	10487007
Inflammation	Altered Intercellular Communication	Pharmaceuticals that block leukocyte adhesion to E-selectin or ICAM-1 may prevent radiation-mediated inflammation in oral mucosa.	10487574
Inflammation, PDR gene, Vitreous strands	Altered Intercellular Communication	The vitreous levels of these sCAMs at the time of surgery may serve as a marker of inflammation, but their specific levels do not predict the likelihood of recurrent proliferation or surgical anatomic success in most cases of PVR and PDR.	10487959
Inflammation, Eales disease, Retinal damage	Altered Intercellular Communication	Increased levels of TBARS and decreased levels of SOD and GSH in the vitreous could explain inflammation, retinal damage and neovascularization in patients with Eales' disease.	10487964
Nasal Polyps, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The development of nasal polyps might be influenced by different factors such as mucosal inflammation.	10488462
temporal pain, Inflammation	Altered Intercellular Communication	Preoperatively, she had not suffered any temporal pain, and no signs of inflammation were detected serologically.	10489146
Asthma, Eosinophilic inflammation	Altered Intercellular Communication	Montelukast reduces airway eosinophilic inflammation in asthma: a randomized, controlled trial.	10489822
Eosinophilic inflammation	Altered Intercellular Communication	These results demonstrate that montelukast decreases airway eosinophilic inflammation in addition to improving clinical parameters.	10489822
Airway structure, asthma chronic	Altered Intercellular Communication	Its efficacy in the treatment of chronic asthma may be due, in part, to the effect on airway inflammation.	10489822
Inflammation	Altered Intercellular Communication	Nitric oxide (NO), which is thought to play a role in primary host defence and inflammation, is produced endogenously within the respiratory tract, mainly from the paranasal sinuses.	10489837
Celiac Disease, Autoimmune Disorder, CTCAE	Altered Intercellular Communication	We investigated whether patients with more than one autoimmune endocrinologic disorder are even more susceptible to celiac disease or have celiac-type mucosal inflammation.	10489930
Inflammation, Fibrosis Assessment, Infectious Lung Disorder	Altered Intercellular Communication	Inflammation, oxidative stress, and recurrent pulmonary infections are major aggravating factors in cystic fibrosis.	10491455
Airway structure	Altered Intercellular Communication	Exhaled carbon monoxide (CO), a product of heme degradation by heme oxygenase 1 (HO-1) which is induced by inflammatory cytokines and oxidants, was therefore tested as a non-invasive marker of airway inflammation and oxidative stress.	10491455
Refractory Cytopenia of Childhood, Renal Cell Carcinoma Pathway, Hypercalcemia, CTCAE	Altered Intercellular Communication	Parathyroid hormone-related protein (PTHrP) has been shown to be the principal cause of humoral hypercalcemia associated with renal cell carcinoma (RCC).	10491530
Inflammation	Altered Intercellular Communication	TM is downregulated and released from the cell membrane into the circulation by ionizing radiation and during inflammation.	10492164
Inflammation, Calculi	Altered Intercellular Communication	Calculi, stone fragments and foreign bodies embedded in the ureteral wall with associated inflammation were defined with sonography and responded to endoscopic therapies.	10492181
Inflammation, Lofgrens syndrome, Erythema Nodosum	Altered Intercellular Communication	Lofgren's syndrome was defined as the association of erythema nodosum or periarticular ankle inflammation with unilateral or bilateral hilar or right paratracheal lymphadenopathy.	10492317
Inflammation, Erythema Nodosum	Altered Intercellular Communication	Erythema nodosum, periarticular ankle inflammation, or both were present at onset in 173 patients (93%).	10492317
Inflammation, Bullous disease	Altered Intercellular Communication	However, these alterations probably reflect general inflammation rather than a specific reaction in a certain bullous disease.	10494709
Thrombus	Altered Intercellular Communication	Hormonal state rather than age influences cut-off values of protein S: reevaluation of the thrombotic risk associated with protein S deficiency.	10494769
Malignant melanoma of choroid, Inflammation	Altered Intercellular Communication	Incomplete spontaneous regression of choroidal melanoma associated with inflammation.	10496402
Lymphoepithelial carcinoma, Inflammation	Altered Intercellular Communication	Five of the 11 cases were lymphoepithelioma-like carcinomas and, in two of them, an unusual foreign body-type inflammation was observed.	10496595
Vasculitis, Disease, Necrosis	Altered Intercellular Communication	The vasculitides constitute a heterogeneous group of diseases characterized by blood vessel inflammation and necrosis with different but frequently overlapping clinical and pathologic manifestations.	10499071
Bronchitis, Chronic, Inflammation, Respiration Disorders	Altered Intercellular Communication	We carried out an epidemiologic pilot study to evaluate the prevalence of H. pylori in patients with chronic bronchitis, a respiratory disease characterized by persistent chronic inflammation, in comparison with a matched control group.	10499486
Inflammation, Fever, CTCAE, Toxic effect, Fatigue	Altered Intercellular Communication	Toxicity was limited to modest local inflammation at the inoculation site as well as low-grade fever and increased fatigue, each affecting fewer than 20% of the patients.	10499601
Cataract, Inflammation	Altered Intercellular Communication	These cytokines may be synthesized by LEC in vitro and play an important role in an autocrine or paracrine manner in the proliferative process of LEC after cataract surgery, which can cause inflammation and aftercataract.	10502054
Bronchitis	Altered Intercellular Communication	This aeromedical disposition was based on the thinking that his long asymptomatic period indicated bronchial inflammation was resolved, bronchial reactivity was improved, and thus the risk of exacerbation was reduced.	10503760
Inflammation	Altered Intercellular Communication	Histological scores of pouch inflammation did not differ between those with and without symptoms of the joints.	10503837
Inflammation	Altered Intercellular Communication	It is not associated with the presence of pouch inflammation.	10503837
Inflammation, Pregnancy Complications, Infectious	Altered Intercellular Communication	Furthermore, Elastase (a decisive marker for inflammation and infectious complications), was measure (ng/L), and found to be slightly higher in patients (102: 25.5-223), than controls (91.8: 45.9-127).	10503954
Ischemia	Altered Intercellular Communication	Therefore, it is important for the formation of new vessels, example, in ischemia, inflammations, and in the healing of wounds.	10503954
Asthma, Nasal inflammation, Rhinitis	Altered Intercellular Communication	In subjects with asthma and rhinitis, as well as in subjects with only rhinitis, sECP levels are possibly influenced by nasal inflammation.	10505459
Communicable Diseases, Inflammation, Coronary heart disease, Atherosclerosis	Altered Intercellular Communication	We conducted a case control study to investigate whether previous infection with cytomegalovirus is associated with coronary heart disease and markers of systemic inflammation, because systemic inflammation may play a role in atherosclerosis too.	10506850
Sepsis, Inflammation, Tumor necrosis	Altered Intercellular Communication	Sensitivity and specificity of various markers of inflammation for the prediction of tumor necrosis factor-alpha and interleukin-6 in patients with sepsis.	10507603
Inflammation	Altered Intercellular Communication	PCT may be an early and better marker of elevated cytokines than the more classic criteria of inflammation.	10507603
Primary sclerosing cholangitis, Cholangitis	Altered Intercellular Communication	Pathologic correlation suggests that these features may be related to underlying perfusion changes and bile duct inflammation in patients with primary sclerosing cholangitis.	10511174
Pain Distress Question, Inflammation	Altered Intercellular Communication	About 91 per cent of the patients were satisfied with loxoprofen in terms of pain control and decreased inflammation.	10511775
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Because of the persistent fever and signs of inflammation, Gallium-scintigraphy was performed, showing abnormal accumulation in the left fronto-parietal region of the brain and the sacral region.	10511961
Inflammation, Caseous necrosis	Altered Intercellular Communication	Dural biopsy specimens showed non-specific granulomatous inflammation of the dura with epithelioid histiocytes and Langerhans type multinuclear giant cells with caseous necrosis, however, with no presence of fungi or tubercle bacilli.	10511963
Inflammation	Altered Intercellular Communication	Superficial endoscopic gastric biopsies showed mild inflammation with plasma cells of polyclonal origin in the mucosa.	10512402
Inflammation, Brain Injuries, Occlusion of artery (disorder)	Altered Intercellular Communication	Ischemic brain injury secondary to arterial occlusion is characterized by acute local inflammation, which involves accumulation of polymorphonuclear neutrophils (PMN).	10512924
Inflammation, Liver Failure	Altered Intercellular Communication	However, these procedures failed to reduce the inflammation, and she expired because of liver failure soon after placing a covered stent in the esophagus.	10513169
Cataract, Inflammation, Iridocyclitis	Altered Intercellular Communication	To report a case of chronic iridocyclitis in young girls and the effect of systemic cyclosporin A for inflammation following surgery for complicated cataract.	10513206
Inflammation, Ocular Hypotension	Altered Intercellular Communication	Severe inflammation and hypotony developed after surgery and persisted after systemic and topical corticosteroids.	10513206
Acute inflammation, Uveitis	Altered Intercellular Communication	Systemic cyclosporin A was useful for postoperative inflammation in this case of uveitis of young girls.	10513206
Inflammation, Asthma	Altered Intercellular Communication	It was concluded that sECP proved to be a reliable marker for monitoring inflammatory events in asthma; inhaled beclomethasone dipropionate dry powder was at least as effective as budesonide in improving lung function and the underlying asthma inflammation.	10513351
Communicable Diseases, Inflammation	Altered Intercellular Communication	IL-8 and defensines may be of the same pathogenetic importance both in infectious and non-infectious inflammation in the kidneys.	10515041
Inflammation	Altered Intercellular Communication	Cytotoxic action of defensines can be related to location of the inflammation in the kidney.	10515041
Inflammation, Pyelonephritis, Glomerulonephritis	Altered Intercellular Communication	IL-8 urine tests can be used in monitoring of inflammation activity and diagnosis of latent glomerulonephritis and pyelonephritis.	10515041
Functional cyst of ovary, Klinefelter Syndrome, Hyperprolactinemia	Altered Intercellular Communication	Her hormonal examination showed hypogonadotropic, secondary ovarian functional defect, and hyperprolactinemia.	10515236
Hamman-Rich syndrome	Altered Intercellular Communication	In conclusion, cryptogenic fibrosing alveolitis is an inflammatory condition which is characterized, like asthma, by a predominance of gene expression for T-helper-2-type regulatory cytokines, whereas cryptogenic fibrosing alveolitis associated with systemic sclerosis appears to have a distinct mixed T-helper-1/T-helper-2 functional phenotype and a greater number of cells expressing each of these pro-inflammatory cytokines.	10515397
Airway structure, ARCN1 gene, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	This study investigated whether IL-10 levels in the airway are decreased in chronic airway inflammation associated with asthma or chronic obstructive pulmonary disease (COPD).	10515406
Airway structure, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	These data suggest that the reduced level of interleukin-10 within the airways plays a role in the pathogenesis of chronic airway inflammation in asthma and chronic obstructive pulmonary disease.	10515406
Infection caused by Helicobacter pylori, Acute and chronic inflammation, Esophagitis	Altered Intercellular Communication	In multivariate analysis, independent risk factors for incomplete junctional IM were age (odds ratio (OR) 1.3 per decade, 95% confidence interval (CI) 1.2 to 1.6), endoscopic erosive oesophagitis (OR 1.9, 95% CI 1.1 to 3.2), and chronic cardia inflammation (OR 2.9, 95% CI 1.3 to 6.2), but not gastric H pylori infection (OR 1.0, 95% CI 0.6 to 1.7).	10517897
Infection caused by Helicobacter pylori, Acute and chronic inflammation	Altered Intercellular Communication	In univariate analysis, junctional complete IM was strongly associated with chronic cardia inflammation and cardia H pylori infection (p<0.	10517897
Inflammation, Gastritis	Altered Intercellular Communication	A mild degree of chronic gastritis characterized both cases, with, focally active inflammation and lymphoid aggregates.	10518387
Inflammation	Altered Intercellular Communication	Vascular permeability/vascular endothelial growth factor (VEGF) is a multifunctional cytokine which plays a role in chronic inflammation and angiogenesis.	10520060
Inflammation	Altered Intercellular Communication	The material was subdivided into two subgroups: 1) tissue from the "infectious" foot with great amount of bacteria and inflammation reaction; 2) tissue from the "ischemic" foot with considerable alterations of microvessels structure.	10520421
Inflammation, Gangrene of gallbladder	Altered Intercellular Communication	Four patients with gallbladder gangrene underwent open cholecystectomy and 23 patients underwent laparoscopic cholecystectomy, of which 15 (65%) were completed laparoscopically and 8 (35%) had open conversion as a result of severe inflammation.	10520915
Inflammation, Atherosclerosis	Altered Intercellular Communication	Plasma concentration of markers of inflammation are increased in patients with atherosclerosis.	10521364
Inflammation, Atherosclerosis	Altered Intercellular Communication	However, these strong univariate associations of markers of inflammation and atherosclerosis were lost in multivariate analysis once age, sex, and high density lipoprotein cholesterol or fibrinogen were taken into account.	10521364
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The purpose of the present study was to investigate the relationship between the mucosal concentration of BPI and the grade of mucosal inflammation in ulcerative colitis.	10521980
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Despite extensive studies, the role of prostaglandins in the course of inflammatory bowel diseases and their possible usefulness as predictive indicators of inflammation, remain largely speculative.	10521993
Mucous Membrane, Inflammation	Altered Intercellular Communication	Because of a good correlation with mucosal injury and PGE2 content, measurement of plasma PGE2 could be considered as a possible surrogate marker of bowel inflammation.	10521993
Inflammation, Hepatobiliary Disorder, Hepatitis, Cirrhotic	Altered Intercellular Communication	Laparoscopic examination revealed chronic hepatitis, but neither active inflammation nor cirrhotic changes were noted as an underlying liver disease.	10522040
Inflammation, Periodontal Diseases	Altered Intercellular Communication	Clinical and biochemical markers of periodontal disease have been used for precise objective diagnosis of periodontal inflammation.	10522776
Nasal inflammation, Cystic Fibrosis	Altered Intercellular Communication	Eosinophilic cationic protein as a marker of nasal inflammation in patients with cystic fibrosis.	10522945
Acute and chronic inflammation	Altered Intercellular Communication	In CF patients with chronic nasal inflammation, increased nasal levels of ECP were detected when compared with asymptomatic CF patients or healthy nonatopic subjects.	10522945
Inflammation, Asthma	Altered Intercellular Communication	There is evidence that eosinophils are involved in inflammation in asthma, a correlation having been observed between blood eosinophil (B-EOS) count and pulmonary function.	10524538
Refractory anemias, Inflammation	Altered Intercellular Communication	Urinary TM levels may allow differentiation of RA subsets, unlike markers of inflammation such as ESR and CRP.	10524552
Inflammation, Necrosis	Altered Intercellular Communication	Shallow mucosa, necrosis and high-grade inflammation were found in the sub-contractor group.	10524636
Inflammation, Superficial ulcer, Functional Disability	Altered Intercellular Communication	Disease outcome was assessed at 2 years in terms of persistent joint inflammation, functional disability, and radiologic erosions.	10524690
Colitis	Altered Intercellular Communication	Histological examination of HLA-B27 rat colons confirmed the colonic inflammation as a chronic active mononuclear cell infiltrate.	10525115
Inflammation	Altered Intercellular Communication	We conclude that the measurement of intestinal permeability by iodixanol excretion is a useful biochemical marker that is associated with increases in colonic weight and histological evaluation of inflammation.	10525115
Communicable Diseases, Inflammation	Altered Intercellular Communication	Infection or inflammation were excluded clinically and with an erythrocyte sedimentation rate <30 mm/h.	10525124
Sarcoma, Epithelioid, Inflammation, Peyronie Disease	Altered Intercellular Communication	Initial presentation of epithelioid sarcoma may provoke considerable diagnostic difficulty, and its differentiation from benign lesions, such as Peyronie's disease and chronic inflammation, may be a clinical problem.	10525872
Inflammation, Specimen Type - Fistula, Deglutition Disorders	Altered Intercellular Communication	Once the inflammation due to the fistula has been controlled, chemoradiotherapy should be utilized because it may provide the best chance for survival and palliation of severe dysphagia.	10526266
Physiologic Intraocular Pressure, Papilledema, Uveitis	Altered Intercellular Communication	In 6 persons (18.2%) variety of ocular lesions was recognized (nodular infiltrations of the eyelids, chronic uveal inflammation, signs of anterior and posterior uveitis in the past, optic disc oedema).	10526445
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Anti-adhesion molecule therapy as an interventional strategy for autoimmune inflammation.	10527685
Infarction, Have Autoimmune or Inflammatory Condition, Tissue injury	Altered Intercellular Communication	Functional inactivation of leukocyte adhesion molecules has been used to intervene in the development of tissue injury in experimental models of postperfusion infarction as well as autoimmune inflammation.	10527685
Refractory anemias, Inflammation, Rheumatoid Arthritis, Synovial Fluid	Altered Intercellular Communication	To clarify involvement of synovial T cells in the development of synovial inflammation in patients with rheumatoid arthritis (RA), we analyzed cellular interactions between synovial cells and infiltrating T cells via CD28/B7-1 and B7-2.	10529123
Refractory anemias, Inflammation	Altered Intercellular Communication	These results suggest that cellular interactions between synovium infiltrating T lymphocytes and synovial cells via B7/CD28 pathways are intimately associated with development and exacerbation of inflammation in RA synovial cells.	10529123
Visual Cortex Disorder, palladium	Altered Intercellular Communication	We conclude, that visual dysfunction and execution of movement are more influenced by altered dopaminergic neurotransmission in PD in comparison to the initiation of movement.	10529760
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	The levels of IL-6 and sIL-6R in organ cultures were substantially elevated in patients with IBD, especially in those with histologically active inflammation.	10530495
Colitis	Altered Intercellular Communication	In contrast, considerably higher levels of sIL-6R were detected in patients with other types of colonic inflammation who were included as inflammatory controls, but elevation of IL-6 was less prominent in such patients.	10530495
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Enhanced IL-6/sIL-6R-mediated immune and inflammatory responses may be implicated, at least partly, in the continuation of intestinal inflammation in patients with IBD.	10530495
Orbital Pseudotumor	Altered Intercellular Communication	Orbital pseudotumor, also known as idiopathic orbital inflammation, is defined as a nonspecific, nonneoplastic inflammatory process of the orbit without identifiable local or systemic causes.	10530975
Epilepsy, Temporal Lobe, Hyperexcitability Behavior	Altered Intercellular Communication	In addition to functionally affected neuronal signaling pathways, altered axonal, dendritic, and synaptic morphology may contribute to hippocampal hyperexcitability in chronic mesial temporal lobe epilepsies (MTLE).	10531538
Communicable Diseases, Inflammation, Failure (biologic function), Pain Distress Question	Altered Intercellular Communication	Pain and inflammation were not common to all failures, and infection was not reported in any of the 5 failures.	10531736
Inflammation	Altered Intercellular Communication	The greatest shifts in the immune status are observed in patients with erosive ulcerative LRP, which is characterized by the greatest severity and intensity of inflammation.	10533387
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Serum PG II levels, but not those of PG I, significantly correlated with the inflammation and activity scores of antrum in dialysis patients, and these scores were highly influenced by H. pylori infection.	10534510
Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	In dialysis patients, high serum levels of PG II, but not PG I, are significantly related to H. pylori infection and mucosal inflammation.	10534510
Inflammation	Altered Intercellular Communication	H. pylori infection appeared to activate T cells to secrete even more IFN-gamma, which may contribute to maintaining a perpetual inflammation in H. pylori-infected stomach.	10535482
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Portal fibrosis (grades 0-3) was present in 62% of patients (grade 2 or 3 in 12%) in association with steatosis, inflammation, and increased age.	10535879
Hepatic inflammation	Altered Intercellular Communication	Unintentional rechallenge led to a second flare of hepatic inflammation in 1 patient.	10535888
Cognition Disorders, Data types - Address	Altered Intercellular Communication	Increased GAL could exacerbate the cognitive and behavioral deficits of AD because GAL acts as an inhibitory modulator of cholinergic and noradren-ergic neurotransmission.	10537062
myocardial injury, Inflammation, Atherosclerosis	Altered Intercellular Communication	We measured plasma levels of IL-6 and sIL-6R in 17 patients with AMI to evaluate changes over time at 11 points in the acute phase and compared them with parameters of inflammation, myocardial injury, and atherosclerosis.	10539822
Inflammation, myocardial injury	Altered Intercellular Communication	These results demonstrate that IL-6 and sIL-6R are associated with the processes of inflammation and myocardial injury during the acute phase of AMI.	10539822
Inflammation, Myositis, CTCAE 5.0, Hypertrophy	Altered Intercellular Communication	This case report highlights the diagnostic difficulties in distinguishing focal myositis and denervation hypertrophy following S-1 radiculopathy or secondary inflammation related to denervation.	10540038
Inflammation, Ophthalmoplegia, Steroid-sensitive nephrotic syndrome, Orbital Pseudotumor	Altered Intercellular Communication	Orbital pseudotumor is characterized by self-limited, relapsing, steroid-responsive painful ophthalmoplegia, and this case could be a variant of this entity with inflammation extending into the extraorbital area.	10540039
Inflammation, Prostate	Altered Intercellular Communication	Of these 68 patients with a histologically demonstrated inflammation of the prostate, only 19 (27.9%) had positive prostatic tissue cultures.	10540763
Inflammation, Apoptosis	Altered Intercellular Communication	Our data thus show that aspiration of meconium leads to severe lung tissue inflammation with early ultrastructural changes in the pulmonary alveolar walls and is associated with apoptotic cell death in the epithelium, already during the first hours after the insult.	10541329
Tuberculosis, Pulmonary, Tumor necrosis, Inflammation, Tuberculosis	Altered Intercellular Communication	Accumulating evidence suggests that patients with active pulmonary tuberculosis (TB) have an alveolar inflammation resulting in the release of tumour necrosis factor (TNF)-alpha and interleukin (IL)-1beta in bronchoalveolar epithelial fluid.	10543265
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Excessive inflammation seems important in chronic obstructive pulmonary disease (COPD), particularly during exacerbations of the disease.	10543270
ARCN1 gene, Asthma, Bronchitis	Altered Intercellular Communication	Exhaled nitric oxide concentration ([NOexh]) is a sensitive marker of bronchial inflammation in asthma; it is unclear if this is also the case in COPD.	10543270
airway disease, Inflammation	Altered Intercellular Communication	These findings may be suggestive of differences in the distribution of inflammation along the airways between distinct airway diseases.	10543295
Refractory anemias, Inflammation, Amyloidosis	Altered Intercellular Communication	We postulate that the allele SAA1gamma renders an RA patient susceptible to amyloidosis, possibly by affecting the severity of inflammation in RA.	10543406
Inflammation, Congenital Abnormality	Altered Intercellular Communication	Type I glands were positive for clinical symptoms and MR imaging abnormalities, and were characterised histopathologically by active inflammation (9 [56%] of 16).	10543651
Ischemia, Lupus Erythematosus, Systemic, Impaired, Vasculitis, Vasospasm	Altered Intercellular Communication	Our results suggest that in the multifactorially determined vascular pathology of SLE, changes associated with I/D polymorphism could influence vessel wall inflammation (monocyte adhesion and activation with cytokine release, T-lymphocyte metabolism), a tendency towards vascular impairment (neointimal proliferation, vasospasm, platelet activation, myocyte proliferation) and lead to the subsequent ischemia.	10544843
Inflammation, Endometrial Carcinoma, Traumatic injury, Keloid	Altered Intercellular Communication	We present a 66-year-old woman who developed eruptive keloids in association with endometrial carcinoma in the absence of trauma, surgery, inflammation, or other known preludes to keloid formation.	10544878
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	In this study, we examined several markers of inflammation in men with coronary heart disease (CHD) and appropriate controls.	10545067
Single organ dysfunction, Inflammation, Community-Acquired Infections	Altered Intercellular Communication	Markers of systemic inflammation predicting organ failure in community-acquired septic shock.	10545303
Shock, Inflammation	Altered Intercellular Communication	However, a sepsis-related inflammation severity score (SISS), developed on the basis of the presence or absence of shock and on the levels of markers at T1, identified each patient that developed OF.	10545303
Doctor of Chiropractic, Myocardial, Myocarditis	Altered Intercellular Communication	In some patients with DCM, myocardial damage secondary to viral or immune-mediated myocardial inflammation may persist.	10545675
Unknown (origin) (qualifier value), Inflammation	Altered Intercellular Communication	To objectively assess inflammation, we measured plasma concentrations of C-reactive protein (CRP) in 188 patients with idiopathic DCM over 5-8 years.	10545675
Sepsis, Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	To assess the effect of plasmafiltration (PF) on biochemical markers of inflammation, cytokines, organ dysfunction, and 14-day mortality in human sepsis.	10548188
Inflammation, septic	Altered Intercellular Communication	Assessment of inflammation marker serum levels in septic vs. nonseptic ARDS.	10548201
Intraocular inflammation	Altered Intercellular Communication	Although significantly more HIV positives had some sign of intraocular inflammation compared to the negatives (p = 0.02) there was no significant linear trend in the HIV positives with decreasing CD4 count.	10548465
Intraocular inflammation	Altered Intercellular Communication	Overall, 11 (26%) prevalent, 6 (10%) incident cases and 8 (6%) HIV-negatives controls had some evidence of intraocular inflammation, however, only one person had reduced visual acuity attributable to these lesions.	10548465
Inflammation, Cerebral Aneurysm	Altered Intercellular Communication	The purpose of the present study is to determine whether inflammation or immunological reaction occurs in cerebral aneurysms.	10549930
Inflammation	Altered Intercellular Communication	The granulomatous inflammation was caused by nonabsorbable lipids introduced by the postoperative nasal tamponade which was soaked in antibiotic ointment.	10550361
Inflammation, Asthma	Altered Intercellular Communication	Increased expression of IL-4delta2 in stable asthmatic subjects suggests that the balance of IL-4 and IL-4delta2 may modulate asthmatic inflammation.	10550742
Inflammation	Altered Intercellular Communication	These findings suggested that chronic inflammation in the pulp tissue had resulted in a draining sinus tract.	10551125
Acute appendicitis NOS (disorder)	Altered Intercellular Communication	Criteria for diagnosis of acute appendicitis included an enlarged appendix (> 6 mm) and periappendiceal inflammation.	10551210
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation and activation of immune cells have important roles in the pathogenesis of atherosclerosis.	10551265
Drug Eruptions, allergic inflammation	Altered Intercellular Communication	These results suggest that infiltrating CD4+ T cells might regulate both peripheral and tissue eosinophils and facilitate allergic inflammation at drug eruptions by means of IL-5 production.	10554428
Cessation of life, Inflammation	Altered Intercellular Communication	Neutrophil apoptosis or programmed cell death regulates functional longevity, and is an integral component of inflammation and its resolution.	10555638
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Eosinophilic inflammation in stable chronic obstructive pulmonary disease.	10556110
Airway structure, ARCN1 gene	Altered Intercellular Communication	Our data suggest that eosinophils may be involved in the airway inflammation of COPD.	10556110
Inflammation, Saint Lucia, Perforation (observation)	Altered Intercellular Communication	Inflammation and a positive history of previous laparotomies play a crucial role in GB perforation at LC.	10556446
Chronic infectious disease, Helicobacter pylori, Inflammation	Altered Intercellular Communication	Chronic infection with Helicobacter pylori does not provoke major systemic inflammation in healthy adults: results from a large population-based study.	10559526
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	We assessed the relation between serological markers of H. pylori infection and various markers of systemic inflammation in a population-based sample of 1834 men and women aged 18-88.	10559526
Chronic infectious disease	Altered Intercellular Communication	These results do not support the hypothesis that chronic infection with virulent H. pylori strains provokes major systemic inflammation.	10559526
Inflammation, Prostatic fluid, prostatitis, Infarction, Cystic duct structure, Acute prostatitis, Calculus of prostate, Prostatic Intraepithelial Neoplasias	Altered Intercellular Communication	Each prostatectomy specimen was weighed and each slide was evaluated for inflammation (acute prostatitis, chronic-active prostatitis and chronic-inactive prostatitis), prostatic intraepithelial neoplasia, transitional/squamous metaplasia, cystic ductal dilation, leiomyoma-resembling stromal cell proliferation, leakage of prostatic secretion, infarction and prostatic calculi.	10559617
prostatitis	Altered Intercellular Communication	No minimal change pathology or prostatic inflammation were associated with preoperative total or free PSA levels.	10559617
Gastroesophageal reflux disease, Inflammation, Helicobacter pylori, Gorontalo Language	Altered Intercellular Communication	The cause of inflammation in cardiac mucosa at the gastro-oesophageal junction (GOJ) is unclear, both gastro-oesophageal reflux disease (GORD) and Helicobacter pylori having been implicated.	10562575
Inflammation	Altered Intercellular Communication	Inflammation in glandular mucosa at the GOJ was present in 99/125 specimens (79%), including 87/96 (91%) with cardiac mucosa and 12/29 (41%) with fundic mucosa.	10562575
Inflammation	Altered Intercellular Communication	Inflammation in fundic mucosa was closely related to H pylori and active inflammation was only seen in its presence.	10562575
Inflammation	Altered Intercellular Communication	However, active inflammation was also found in 34/68 (50%) cardiac mucosa specimens without H pylori.	10562575
Inflammation	Altered Intercellular Communication	In H pylori colonised patients, inflammation was seen throughout the stomach, while in non-colonised patients, it was confined to cardiac mucosa.	10562575
Inflammation, GDC Disease Response Terminology, Autoimmune Diseases, Diabetes Mellitus, Diabetes Mellitus, Insulin-Dependent	Altered Intercellular Communication	The pattern of inflammation, expression of HLA class II DR by breast epithelium and association with autoimmune disorders, particularly insulin dependent diabetes mellitus (IDDM), together suggest an autoimmune aetiology.	10562813
Inflammation, Stricture of anus, Hyperostosis	Altered Intercellular Communication	We supposed that spread of an inflammation by mucocele was able to cause regional hyperostosis in the wall of the ethmoidal sinus, which led to optic canal stenosis.	10565053
Gastroesophageal reflux disease, Inflammation, Carditis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Chronic inflammation at the gastroesophageal junction (carditis) appears to be a specific finding related to Helicobacter pylori infection and gastroesophageal reflux disease.	10566710
Inflammation, Helicobacter pylori, Gastritis, Gastroesophageal reflux disease, Carditis	Altered Intercellular Communication	The clinical significance of chronic inflammation at the gastroesophageal junction (carditis) is unknown: it may be associated with Helicobacter pylori (H. pylori) gastritis or with gastroesophageal reflux disease (GERD).	10566710
Inflammation, Carditis	Altered Intercellular Communication	Chronic inflammation at the gastroesophageal junctional mucosa (carditis) was detected in 790 (75%) of 1053 patients.	10566710
Gastroesophageal reflux disease, Inflammation, Helicobacter pylori, Cardia of stomach	Altered Intercellular Communication	Two dissimilar types of chronic inflammation of the gastric cardia mucosa seem to occur, one existing in conjunction with chronic H. pylori gastritis and the other with normal stomach and erosive GERD.	10566710
Intestinal metaplasia, Helicobacter pylori, Gastritis	Altered Intercellular Communication	Most cases of chronic gastric cardia inflammation and intestinal metaplasia are detected in patients with chronic H. pylori gastritis.	10566710
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	Traditionally, contiguous distribution of inflammation (endoscopic and histological) with rectal involvement is thought to be important in distinguishing ulcerative colitis (UC) from Crohn's disease of the colon.	10566726
Intestinal metaplasia, Inflammation, Gastritis, Atrophic	Altered Intercellular Communication	Presence of gastritis and grading of inflammation, activity, intestinal metaplasia and atrophy were ascertained using Sydney System.	10568114
Inflammation, Atrophic	Altered Intercellular Communication	Labeling Index was significantly higher in H. pylori positive subjects (p < 0.005) and it was correlated with inflammation and atrophy (p = 0.001).	10568114
Acute inflammation	Altered Intercellular Communication	There was a trend for patients who had CME at day 60 to have more postoperative inflammation.	10569164
prostatitis	Altered Intercellular Communication	The term prostatitis is based on the presumption that prostatic inflammation is important in the pathophysiology of this syndrome.	10569559
prostatitis	Altered Intercellular Communication	Prostate histopathology in 368 biopsies from 97 patients with the chronic prostatitis/chronic pelvic pain syndrome was characterized.. Prostatic inflammation was detected in only 33% of patients, including 29% with mild (less than 10 leukocytes per 1 mm.	10569559
Inflammation	Altered Intercellular Communication	The finding of moderate or severe inflammation in only 5% of 97 patients argues for the need to reevaluate current concepts of the pathophysiology of the chronic prostatitis/chronic pelvic pain syndrome.	10569559
Celiac Disease, PAPILLARY STENOSIS, Duodenal inflammation	Altered Intercellular Communication	We hypothesize that celiac disease may also be associated with pancreatico-biliary abnormalities due to duodenal inflammation and papillary stenosis.	10570344
Celiac Disease, Inflammation	Altered Intercellular Communication	These 12 patients had manometric evidence of stenosis and histologic evidence of periampullary inflammation as well as histologic changes consistent with celiac disease.	10570344
Inflammation, Ototoxicity	Altered Intercellular Communication	With this in mind, we have scanned multiple alignments of expressed sequence tags and of genomic DNA sequences (PCR products from four to eight unrelated individuals) to find polymorphisms in 195 genes putatively involved in neurodegenerative illness (including components of oxidative stress, excitotoxicity, inflammation, apoptosis and aging).	10570959
No ocular symptoms, Fibrosis Assessment, Conjunctivitis, Photophobia	Altered Intercellular Communication	Reduction in conjunctival inflammation, prevention of progression of subepithelial conjunctival fibrosis, improvement in ocular symptoms (discomfort, photophobia), improved visual acuity, reduction in extraocular mucosal lesions.	10571350
Inflammation, Helicobacter pylori	Altered Intercellular Communication	In addition, it has been reported that Helicobacter pylori induced inflammation of the gastric mucosa may affect gastric motility.	10571604
Airway structure	Altered Intercellular Communication	Downregulation of IL-16 expression by dexamethasone suggests that glucocorticoids may inhibit airway inflammation partly by suppressing the synthesis of inflammatory cytokines including IL-16.	10572065
Communicable Diseases, Inflammatory abnormality of the eye, Drug-induced, Allergic	Altered Intercellular Communication	External factors were: toxic, allergic, drug-induced, ocular surface inflammation and infection, contact lens and generally external irritations.	10572884
Meningitis	Altered Intercellular Communication	Concentrations of these drugs were measured in serum and cerebrospinal fluid in the presence and absence of meningeal inflammation.	10573317
Inflammation, Atrophic	Altered Intercellular Communication	Inflammation and atrophy was graded from biopsies from multiple sites in the antrum and body.	10574133
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	Gastric juice ascorbic acid concentration was not associated with age, endoscopic diagnosis or intestinal metaplasia, but was significantly associated with the degree of acute inflammation (P = 0.01) and the presence of atrophy (P = 0.04).	10574133
Intestinal metaplasia, Helicobacter pylori, Gastritis, Gastro-esophageal reflux disease with esophagitis	Altered Intercellular Communication	Gastric cardia inflammation and intestinal metaplasia: associations with reflux esophagitis and Helicobacter pylori.	10574598
Intestinal metaplasia, Gastritis	Altered Intercellular Communication	Gastric cardia inflammation and intestinal metaplasia are the subjects of recent investigation.	10574598
Keratinized squamous cell of esophagus, Inflammation, Nocardia Infections	Altered Intercellular Communication	Cardia inflammation was significantly related to esophageal squamous inflammation in the non-HP-infected patient group and to antral inflammation and cardia HP infection in the HP-infected patient group.	10574598
Inflammation	Altered Intercellular Communication	The differences between the patient groups was most apparent in the patients with moderate or marked inflammation.	10574598
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	Twenty-seven percent of patients had cardia intestinal metaplasia that was related to cardia inflammation.	10574598
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	Cardia inflammation and intestinal metaplasia probably have multiple causes.	10574598
Inflammation, Traumatic neuroma	Altered Intercellular Communication	In 39 neurotrauma patients, a temporal correlation between the protease release from neutrophils and the solubilization of interleukin-2 (IL-2) receptor and IL-6 receptor ectodomains at sites of tissue destruction was observed, suggesting that neutrophil-derived proteases may play a crucial role in the cytokine receptor shedding at foci of inflammation.	10574621
allergic inflammation	Altered Intercellular Communication	Activation of p38 MAPK and the resulting induction of apoptosis in EoL-1 cells may be important to explain the anti-inflammatory action of NSAID in allergic inflammation.	10574634
Granulomatous inflammation	Altered Intercellular Communication	A punch biopsy of the tip of the third toe showed granulomatous inflammation.	10575159
Inflammation, Necrosis	Altered Intercellular Communication	These cytokines are usually administered subcutaneously, and recent studies have described the occurrence of inflammation or necrosis at the site of injection.	10575164
Inflammation, Necrosis	Altered Intercellular Communication	Cutaneous inflammation or necrosis at interferon injection sites is not uncommon.	10575164
Granulomatous inflammation, Pleural Tuberculosis	Altered Intercellular Communication	Diagnosis of tuberculous pleurisy was based on histologic evidence of caseating granulomatous inflammation in the pleural biopsy specimen, or evidence of mycobacteria in pleural fluid.	10575837
Pancreatitis	Altered Intercellular Communication	In severe cases operative endoscopy cured pancreatic inflammation in 13 cases.	10575889
Inflammation, Secondary malignant neoplasm of skin	Altered Intercellular Communication	Biopsy of the pericardial and fat tissues revealed an inflammation and normal fat cells without any malignant cell infiltration.	10576155
Intraocular inflammation, Vitreous opacities, Retinitis, Cataract, Vasculitis, CTCAE	Altered Intercellular Communication	A 77-year-old man was initially seen with visual acuity of 20/200, focal retinitis, vasculitis, and progressive vitreous opacity in the right eye and visual acuity of light perception, intraocular inflammation, and a dense cataract in the left eye 14 months after intravesicular injection of live bacille Calmette-Guerin organisms.	10577542
Inflammation, Atherosclerosis	Altered Intercellular Communication	Cytomegalovirus in the pathogenesis of atherosclerosis: the role of inflammation as reflected by elevated C-reactive protein levels.	10577564
Communicable Diseases, Inflammation, Coronary Artery Disease	Altered Intercellular Communication	We hypothesized that cytomegalovirus (CMV) infection: 1) stimulates an inflammatory response, reflected by elevated C-reactive protein (CRP) levels, and 2) predisposes to coronary artery disease (CAD), in part, through CMV-induced inflammation.	10577564
Inflammation, Cytomegalovirus	Altered Intercellular Communication	We believed that CMV exerted an atherogenic effect by inducing inflammation, and the disparate results may derive partly from individual variability in the capacity to control CMV inflammatory activity.	10577564
Inflammation, Uveitis	Altered Intercellular Communication	Review of data from all patients with uveitis who underwent trabeculectomy for uncontrolled intraocular pressure secondary to intraocular inflammation between May 1990 and December 1994.	10577584
Intraocular inflammation	Altered Intercellular Communication	Maximum control of intraocular inflammation was achieved for a minimum of 2 months before surgery.	10577584
Inflammation, Uveitis	Altered Intercellular Communication	In the absence of other risk factors, such as Afro-Caribbean race and previous intraocular surgery, and with adequate preoperative control of inflammation, trabeculectomy without antimetabolites may be considered the primary surgical procedure for increased intraocular pressure in patients with uveitis.	10577584
Inflammation, alpha 1-Antitrypsin Deficiency, Ulcerative Colitis	Altered Intercellular Communication	The increased frequency of heterozygosity for the PiZ variant of AAT deficiency among patients with UC might imply a role played by protease inhibitors for regulation of inflammation and immunologic response in UC.	10579117
Inflammation, Regular atrial cardiac myocyte, myonecrosis	Altered Intercellular Communication	Inflammation was usually associated with myocyte atrophy and only rarely with myonecrosis.	10579739
Inflammation, Lafora body, Neuronal loss in central nervous system, Neoplasms	Altered Intercellular Communication	A routine neuropathological examination showed no pronounced changes, such as neuronal loss, morphologically abnormal neurons, inflammation, vascular changes, Lafora bodies and tumor cells, except that mild gliosis was seen only in CA4 of the hippocampus.	10580554
Uveitis	Altered Intercellular Communication	A single episode of mild to moderate acute uveal inflammation with resolution in a few weeks or more occurred in 44 (62.9%) patients, and multiple episodes in 26 (37.1%), with a mean interval of 16 months (range, 1-250 months), which affected the same eye, fellow eye, or both.	10580663
Granulomatous inflammation, Sarcoidosis, Alveolitis	Altered Intercellular Communication	Leads to the etiology of sarcoidosis have come from diverse sources: in clinical laboratory investigations, alveolitis has been found to precede granulomatous inflammation; in case control studies, familial aggregation has been identified; and in case reports, recurrence of granulomatous inflammation has been observed after lung transplantation.	10580780
Brain Injuries	Altered Intercellular Communication	Controlling the extent of inflammatory responses following brain injury may be beneficial since posttraumatic intracranial inflammation has been associated with adverse outcome.	10580806
Inflammation, Injury of cornea	Altered Intercellular Communication	In experimental studies, most methods of inducing recurrence have involved some degree of corneal trauma, inflammation, neuronal stimulation, or damage to the nerves that innervate the cornea.	10584428
Inflammation, Cytopathogenic Effect, Viral, Fibrosis Assessment, Neoplasms	Altered Intercellular Communication	The histological findings of the primary tumor and metastatic lymph nodes demonstrated massive cancer cell degeneration such as pycnosis and vacuolation, xanthogranulomatous inflammation and dense fibrosis.	10584574
Inflammation, Pancreatitis	Altered Intercellular Communication	Ten patients had an inflammation of the entire pancreas, while one had pancreatitis localized to the body and tail of the pancreas.	10584648
Inflammation, Pancreatitis	Altered Intercellular Communication	Of the nine patients with inflammation of the entire pancreas, six showed the distribution of contrast material to the entire area of pancreatic inflammation (a good distribution) on the CTA, and the remaining three did not show the distribution of contrast material to cover the entire area of pancreatic inflammation (a poor distribution).	10584648
Inflammation, Diarrhea	Altered Intercellular Communication	Endoscopic examination of a patient with severe loperamide-resistant diarrhea after CPT-11 chemotherapy revealed an inflammation of the ileo-coecal region.	10586346
Sepsis, Inflammation	Altered Intercellular Communication	In recent models, compensatory antiinflammatory immune reactions triggered in response to systemic inflammation were considered important for the outcome of sepsis.	10587185
Inflammation, Infection caused by Helicobacter pylori, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	There is controversy about the association between Helicobacter pylori infection and manifestations of coronary heart disease (CHD), the potential role of the more virulent H pylori strains, and whether or not a positive serostatus is related to increased levels of markers of systemic inflammation.	10587336
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Between 1989 and 1997, 1035 patients underwent surgery for an abdominal aneurysm, 42 of whom (4.1%) had typical signs of inflammation.	10587394
Inflammation, Fibrosis Assessment, Entrapment of Device	Altered Intercellular Communication	Although ureteral involvement to the inflammation tends to subside after surgery, persisting fibrosis was associated with ureteral entrapment in 30% of these cases and resulted in renal compromise in 49%.	10587394
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide (ENO) is a surrogate marker of airway inflammation in asthma.	10587413
Inflammation	Altered Intercellular Communication	These data suggest that the spread of root resorption is associated with inflammation.	10588491
Inflammation, Infectious Lung Disorder, Bronchiectasis	Altered Intercellular Communication	Neutrophil-related inflammation associated with a decrease in CD4+ lymphocyte might reflect the progression of pulmonary MAI infection with nodular bronchiectasis.	10588596
Chronic Obstructive Airway Disease, alpha 1-Antitrypsin Deficiency, Bronchitis	Altered Intercellular Communication	Evidence for excessive bronchial inflammation during an acute exacerbation of chronic obstructive pulmonary disease in patients with alpha(1)-antitrypsin deficiency (PiZ).	10588615
Bronchitis	Altered Intercellular Communication	The increased bronchial inflammation at presentation resolved rapidly with 14 d of antibiotic therapy.	10588615
Granuloma, Inflammation	Altered Intercellular Communication	Pathologic examination of the placenta was performed, but there were no granulomas or features of chronic inflammation.	10589410
Inflammation, Hepatitis	Altered Intercellular Communication	Total inflammatory activity scores decreased from 8 to 6 (median, NS), but interface hepatitis score (P=0.02) and lobular inflammation score (P=0.006) improved significantly.	10589947
Fibrosis, Liver, Hepatic inflammation, Hepatitis B, Chronic	Altered Intercellular Communication	Famciclovir improves not only biochemical and virological features but also hepatic inflammation and liver fibrosis in patients with chronic hepatitis B under heavy immunosuppression.	10589947
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Markers of inflammation, such as C-reactive protein (CRP) and fibrinogen, have been shown to be predictive of cardiovascular disease.	10590187
Inflammation, Overweight, Obesity	Altered Intercellular Communication	To test whether overweight and obesity are associated with low-grade systemic inflammation as measured by serum C-reactive protein (CRP) level.	10591334
Inflammation, Overweight	Altered Intercellular Communication	These findings suggest a state of low-grade systemic inflammation in overweight and obese persons.	10591334
Inflammation	Altered Intercellular Communication	Malakoplakia, an inflammation usually affecting the urogenital tract, is rarely found in the colon, with only 35 cases published until now.	10591954
Conjunctival congestion	Altered Intercellular Communication	Inflammation of the right eyelid and conjunctival congestion, probably initiated or aggravated by the larvae, were found.	10593102
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Awareness of the CT findings of BALTOMA can help to avoid misinterpreting BALTOMA as chronic inflammation and/or lung carcinoma.	10593284
Inflammation, Seizures, Rasmussen Syndrome, Hemiparesis, Chronic disease, Epilepsy	Altered Intercellular Communication	Rasmussen's syndrome is a chronic disorder characterized by uncontrollable focal seizures and eventually epilepsia partialis continua, ipsilateral hemiparesis, developmental arrest, and cerebral inflammation.	10593678
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histologically, endoneurial edema, fibrosis, focal chronic inflammation, and extensive "onion bulb" formation were seen.	10595765
Inflammation, Thrombosis	Altered Intercellular Communication	The course was complicated by recurrent inflammation and thrombosis of the port catheter.	10596292
Inflammation, Cyst Formation, Fibrosis Assessment, Lung diseases	Altered Intercellular Communication	In every "blind resection" case the pathology revealed lung disorders: cystic deformation, fibrosis or inflammation.	10596318
Airway structure, Chronic Obstructive Airway Disease, Bronchitis	Altered Intercellular Communication	It is suggested that the progressive irreversible airflow obstruction was due to persistent structural change to the airway secondary to eosinophilic airway inflammation, and it is further speculated that eosinophilic bronchitis may be a prelude to chronic obstructive pulmonary disease in some patients.	10596716
Inflammation	Altered Intercellular Communication	The kallikrein-kinin system involves a biologically complex set of interactive proteases that signal the first-line onset of inflammation and associated cellular processes.	10596857
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Gastric antral and pyloric biopsy tissue was histologically examined for degrees of inflammation and H. pylori infection, and then immunolabelled for tissue kallikrein and kinin receptors.	10596857
Bipolar Disorder, Osteoporosis, Postmenopausal, Depression, CTCAE, Osteoporotic Fractures, Osteopenia	Altered Intercellular Communication	In conclusion, notwithstanding the clinical pattern of postmenopausal osteoporosis can lead to depression and, on the other hand, hormonal and behavioral disturbances reported in depression might be enhancing factors for accelerated bone loss, our present results do not support the hypothesis that otherwise healthy postmenopausal women with increased depressive complaints are also more prone to exhibit osteoporotic fractures.	10597877
Pain Distress Question, Inflammation, Malnutrition, Anxiety, CTCAE 3.0, Cessation of life	Altered Intercellular Communication	Conversely, in the second group (patients with impaired cognition) the presence of pain was significantly associated with a serious alteration of the somatic status (malnutrition, inflammation, bedridden status), poor prognosis (long-lasting hospitalization, death), and the presence of anxiety.	10598148
Inflammation, Fibrosis Assessment, Suppurative inflammation, Tuberculosis	Altered Intercellular Communication	In another cases non-specific inflammation (31%), lung fibrosis (1%), tuberculosis (1%), purulent inflammation (1%), blood (7%) were recognized.	10598484
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Idiopathic hypertrophic cranial pachymeningitis is a rare disease, of undetermined pathogenesis, that is characterized by inflammation and fibrosis of the dura mater.	10598701
Inflammation, Chronic ulcer of lower extremity	Altered Intercellular Communication	Our results suggest that loss of CD59 may enhance deposition of TCC and that complement-dependent inflammation may be an important factor in the tissue-damaging processes seen in chronic leg ulcers.	10598871
Inflammation, Aortitis	Altered Intercellular Communication	Perioperaitve steroid therapy plays an important role in preventing complications after AVR when the valve replacement is carried out during the active phase of the inflammation, and for patients with non-Takayasu's aortitis, aortic root replacement should be considered to reduce the tension on the suture line and the native aortic valve annulus.	10598896
Inflammation	Altered Intercellular Communication	However, in case of subacute, chronic inflammation, neither elevated blood flow nor high blood-pool activity may be seen.	10599073
Osteitis	Altered Intercellular Communication	LeukoScan is shown to be more sensitive in case of subacute bone inflammation compared with three-phase bone scanning.	10599073
Inflammation, Unspecified visual loss	Altered Intercellular Communication	Early treatment controlled posterior scleral inflammation and limited visual loss.	10599675
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Minimal effects of pathology (chronic inflammation with rheumatoid arthritis) were found on the hormonal changes in knee patients.	10600661
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Minimal effects of pathology (chronic inflammation with rheumatoid arthritis) were found on the hormonal changes in knee patients.	10600661
Inflammation, Sarcoidosis	Altered Intercellular Communication	IS is an effective non-invasive technique to identify CD4+ inflammation which distinguishes sarcoidosis from other NG-ILDs.	10603633
Inflammation, Motor retardation, Infection, Edema, Alopecia	Altered Intercellular Communication	A repair defect was found similar to that in xeroderma pigmentosum group D. The patient experienced a worsening of psychomotor retardation and episodes of hair loss with edema and inflammation of the scalp resulting from infections.	10604009
Inflammation, Dental Plaque	Altered Intercellular Communication	In humans, skin contamination is the rule, causing first a vesiculopustulous lesion which progresses to an escarrotic plaque with peripheral inflammation localized on exposed areas.	10604013
Prostate carcinoma, prostatitis	Altered Intercellular Communication	We determined whether prostatic inflammation varied by race and could account for the racial difference in PSA among prostate cancer patients.	10604330
Inflammation, Prostate carcinoma	Altered Intercellular Communication	To our knowledge no significant racial difference exists in the extent of inflammatory infiltrate, and inflammation was not the etiology of the racial difference in serum PSA levels in this clinically localized prostate cancer cohort.	10604330
Cholangiocarcinoma, Pancreatitis, Inflammation, Stenosis, Malignant - descriptor, Pancreatic carcinoma	Altered Intercellular Communication	Strictures were malignant in 57 cases (31 pancreatic carcinoma, 20 cholangiocarcinoma, 6 others) and benign in 21 cases (11 chronic pancreatitis, 5 chronic nonspecific inflammation, 5 others).	10604612
Inflammation, Villous atrophy	Altered Intercellular Communication	Duodenal biopsies showed non-specific chronic inflammation while jejunal biopsies from one case revealed grade II villous atrophy with moderate cellular infiltration of lamina propria.	10605499
Inflammation	Altered Intercellular Communication	It is characterized by recurrent episodic inflammation of cartilaginous structures (nose, ear and trachea).	10605566
Inflammation, Pain Distress Question, Tinnitus, Deafness of left ear, diabetic	Altered Intercellular Communication	A 61-year-old diabetic man, with bilateral relapsing aural inflammation, left ear deafness with tinnitus and pain at the sternocostal junctions is reported.	10605566
Muscle damage, Immobile, Granulation finding, Laryngitis	Altered Intercellular Communication	Nasogastric tubes may cause posterior laryngeal inflammation, granulations, muscle damage, and vocal cord immobility.	10605913
Inflammation, Myeloid	Altered Intercellular Communication	Myeloid related proteins (MRP) 8 and 14 and the heterodimer MRP8/14 are myeloid differentiation markers present on infiltrating tissue macrophages in inflammation but not on resident tissue macrophages.	10606357
Inflammation, Rheumatoid Arthritis, Cardiovascular Diseases	Altered Intercellular Communication	Extent of inflammation predicts cardiovascular disease and overall mortality in seropositive rheumatoid arthritis.	10606363
Refractory anemias, Inflammation	Altered Intercellular Communication	The study emphasizes the importance of inflammation as an important risk indicator for CVD and mortality in RA.	10606363
Giant Cell Arteritis, Inflammation, GCA gene, Amyloidosis	Altered Intercellular Communication	Although giant cell arteritis (GCA) is characterized by chronic inflammation, secondary (AA) amyloidosis appears to be an exceptionally rare complication of this disorder.	10606387
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	In all nine patients biopsied at the 2-year follow-up, liver inflammation had disappeared totally (grade=0), and the stage (fibrosis) had improved.	10607236
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	A significant improvement in inflammation was noted, in patients with a virological LTR, from 3.6 to 0.2 (P<0.01) and in fibrosis from 2.0 to 1.4 (P<0.05) whereas the corresponding scores for patients with a virological non-LTR did not change significantly, from 3.1 to 1.5 for inflammation and for fibrosis from 1.3 to 1.3.	10607236
Inflammation, Lung Diseases, Interstitial	Altered Intercellular Communication	There was increased expression of adhesion receptors (CD11c, CD29, CD36, CD44, CD49e, CD54), receptors involved in signal transduction and/or inflammation (CD13, CD45, CD53), and other markers (CD9, CD52, CD71, CD98, HLA Class I) on macrophages from ILD patients compared to the non-ILD group.	10607488
Blepharoptosis	Altered Intercellular Communication	Compression of the central caudal nucleus in the dorsal midbrain is proposed as the cause of this ptosis, and an alteration of central acetylcholine neurotransmission may contribute to ocular fatigability.	10608681
Inflammatory abnormality of the eye	Altered Intercellular Communication	The Campath-1H mAb was administered to patients with severe, refractory, ocular inflammation.	10611109
Hypochlorhydria, Gastritis, Atrophic, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Eradication of H. pylori infection produced resolution of the gastric inflammation in each subject and resolution of hypochlorhydria and atrophy in 50% of the subjects.	10611150
Inflammatory abnormality of the eye, Ventricular Fibrillation, Uveitis	Altered Intercellular Communication	None of the sera from patients with or without uveitis contained a detectable level of sFas L. sFasL levels in AH and VF are elevated in the eye during ocular inflammation.	10611715
Inflammation, Uveitis	Altered Intercellular Communication	Fas-FasL mediated apoptosis may play an important role in the regulation of inflammation during uveitis.	10611715
Inflammation, Respiratory Tract Infections	Altered Intercellular Communication	In the described case, a 30 year-old man developed severe inflammation of the oral mucous membranes following respiratory infection with Mycoplasma pneumoniae.	10611837
Inflammation	Altered Intercellular Communication	This may be sufficient to initiate events leading to central nervous system inflammation and ultimately to HAM.	10612646
Edema of eyelid, Dacryoadenitis	Altered Intercellular Communication	Eyelid edema due to lacrimal gland inflammation was resolved after local injections of cortisone.	10612861
Inflammation, Pelvic Neoplasms, Actinomycosis	Altered Intercellular Communication	Actinomycosis should be entertained as a possible diagnosis in all cases associating a pelvic tumor and inflammation in women wearing an intrauterine device.	10613196
Inflammation, Traumatic injury	Altered Intercellular Communication	There was no previous knee trauma nor could any inflammation be found.	10613245
Inflammation, Traumatic injury	Altered Intercellular Communication	Inflammation at Calot's triangle is an important associated factor for injury.	10613280
Hepatitis	Altered Intercellular Communication	In non-cirrhotic ALD, stellate cells may be involved in lipid transport and a cytokine network may influence liver inflammation.	10614721
Renal cyst, Cystitis	Altered Intercellular Communication	Insignificant lesions included bladder inflammation in 46 patients and renal cysts in 5.	10614970
Inflammation, atherosclerotic	Altered Intercellular Communication	Neovascular expression of VE-cadherin in human atherosclerotic arteries and its relation to intimal inflammation.	10615428
Giant Cell Arteritis, Inflammation, GCA gene	Altered Intercellular Communication	Macrophages are present in inflammation of the arterial wall and are thought to participate in the pathogenesis of giant cell arteritis (GCA).	10616010
Inflammation, cell injury, Gout	Altered Intercellular Communication	Gout involves seven aspects: (1) uric acid overproduction from increased purines in the diet; (2) uric acid overproduction from ATP degradation; (3) uric acid overproduction from increased de novo synthesis of purines; (4) uric acid overproduction from increased DNA breakdown from cell damage; (5) decreased uric acid elimination, caused by molybdenum and sulfur binding to copper in the kidneys; (6) precipitation of sodium urate-iron crystals in the joints due to high ferritin and saturated transferrin and low CuZn-SOD and Cu-thionein in the joint; (7) development of inflammation, triggered by tyrosine bonding to the sodium-urate-iron crystals and being transformed by tyrosine kinase.	10616042
Hyperglycemia, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Type II diabetes is an hemorheological disease in which hyperglycemia increases the shear stress contributing to inflammation and dysfunction of endothelium.	10616861
Rupture, Electrocardiogram: myocardial infarction (finding), Inflammation, Myocardial Preinfarction Syndrome	Altered Intercellular Communication	Plaque rupture causes the sudden onset of acute myocardial infarction or unstable preinfarction angina, which may be aggravated by smoking and inflammation.	10618338
Inflammation, Acute myocardial infarction, Leukocytosis	Altered Intercellular Communication	Inflammation associated with acute myocardial infarction (AMI) is frequently marked by a peripheral leukocytosis and relative neutrophilia.	10618568
Airway structure, Asthma	Altered Intercellular Communication	Exacerbations of asthma are likely to be due to an increase in airway inflammation.	10619799
Airway structure, Exacerbation of asthma	Altered Intercellular Communication	We have studied noninvasive markers of airway inflammation in asthma exacerbations induced by reducing the dose of inhaled corticosteroids.	10619799
Asthma, Bronchitis	Altered Intercellular Communication	The cause of asthma, which has been linked to a chronic, T-cell-mediated bronchial inflammation, remains unclear.	10619818
Airway structure, Asthma	Altered Intercellular Communication	The GS-sensitive increase in Qaw and its hyporesponsiveness to albuterol in asthmatic subjects may be consequences of airway inflammation.	10619834
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	Continuous hepatic inflammation predisposes the structure of the liver to fibrosis.	10621924
Tissue damage, Inflammation, Dystrophic calcification, Skin	Altered Intercellular Communication	Dystrophic calcinosis is a more common form of calcinosis cutis; calcium salts are deposited secondary to local inflammation, tissue damage and degeneration.	10622063
Communicable Diseases, Inflammation	Altered Intercellular Communication	In contrast, in patients undergoing cardiac surgery associated with cardio-pulmonary bypass, a group of patients with inflammation in the absence of infectious insult, none of the studied IL-8 productions were affected.	10623443
Mediastinitis	Altered Intercellular Communication	If the processes spread toward the mediastinum because of the communication space between medial and deep fascial layer with mediastinum, it could be mediastinal inflammation with high mortality.	10624393
Neck Injuries, Abscess, Lymphoma, Pharyngitis	Altered Intercellular Communication	In the rest of 8 patients abscesses developed as: oropharyngeal inflammation (4 patients), foreign body perforation of esophagus, chronic otitis media, neck injury, malignant lymphoma.	10624393
Inflammation, Esophageal Perforation, Pulmonary Emphysema	Altered Intercellular Communication	In 2 patients neck emphysema developed: anaerobic inflammation in one patient and esophageal perforation in the second.	10624393
Abscess	Altered Intercellular Communication	Deep neck abscesses and phlegmons are relatively rare inflammations in spite of high incidence of surrounding tissue inflammations.	10624393
Bronchitis	Altered Intercellular Communication	Assessment of bronchial inflammation using an automated cell recognition system based on colour analysis.	10624773
Bronchitis	Altered Intercellular Communication	Regarding bronchial inflammation, it was found that the number of inflammatory cells was significantly higher in smokers than in nonsmokers, the majority of these cells bearing immunoglobulin E. These results demonstrate that such computerized analysis of colours is a valuable method for quantifying inflammatory cells in bronchial tissue and for analysing the expression of different markers by a single cell.	10624773
Inflammation, Necrosis	Altered Intercellular Communication	Most consistently, the viruses caused necrosis in respiratory epithelium of the nasal cavity, trachea, bronchi, and bronchioles with accompanying inflammation.	10627555
Inflammation, Diffuse alveolar hemorrhage	Altered Intercellular Communication	Histologically, the areas of consolidation represented active inflammation and intraalveolar hemorrhage containing Aspergillus organisms.	10628453
Inflammation	Altered Intercellular Communication	Increases were proportional to the severity of the inflammation.	10629077
Inflammation, Hemorrhage, Necrosis, Fibrosis Assessment, Infarction, Microcystic degeneration, Squamous metaplasia	Altered Intercellular Communication	Alterations included squamous cell metaplasia (8 cases), infarction and necrosis (4 cases), subepithelial stromal hyalinization (3 cases), acute and chronic hemorrhage and inflammation with multinucleated giant cells (all cases), granulation tissue with subsequent fibrosis (all cases), cholesterol cleft formation (1 case), pseudoxanthomatous reaction (1 case), pseudocapsular invasion (1 case), and microcystic degeneration (2 cases).	10629137
Inflammation, Primary malignant neoplasm, Atrophic, Malignant Neoplasms	Altered Intercellular Communication	Moderate-to-severe atrophy confounded 59% of cases with ASAP and 35% of cancers (P =.003); both ASAP foci and cancer were associated with inflammation in about a quarter of cases.	10629139
Exanthema	Altered Intercellular Communication	Duodenojejunal inflammation may be the primary manifestation of HSP, even in the absence of the characteristic rash.	10630435
Tumor necrosis, Inflammation, Tuberculosis	Altered Intercellular Communication	We investigated the possibility that the large pulmonary cavity in tuberculosis (TB) lesions might result from imbalances between tumor necrosis factor-alpha (TNF-alpha) and soluble TNF-alpha receptor forms (sTNF-RI and sTNF-RII), and interleukin-beta (IL-1beta) and IL-1 receptor antagonist (IL-1RA) in sites of local inflammation.	10631206
Inflammation, Hepatic granuloma	Altered Intercellular Communication	The most common hepatic finding was portal lymphohistiocytic inflammation; discrete hepatic granulomas were seen in less than 20% of involved livers.	10631859
Inflammation	Altered Intercellular Communication	There was no sign of acute or chronic inflammation.	10632007
Hyperplasia, Granulomatous inflammation, Prostate carcinoma, Prostatic Intraepithelial Neoplasias, Atrophic	Altered Intercellular Communication	We conclude that misinterpretation of prostate cancer in transurethral resection specimens results from overdiagnosis of small microscopic foci of hyperplasia, atrophy, prostatic intraepithelial neoplasia, and granulomatous inflammation.	10632121
Inflammatory Bowel Diseases, HD Term Type, Inflammation	Altered Intercellular Communication	Our findings indicate that HD arising in the setting of IBD or chronic inflammation is the result of an Epstein-Barr virus-driven lymphoproliferation, analogous to that found in other immunodeficient states.	10632489
Refractory anemias, Rheumatoid Arthritis, Inflammation, Pain Distress Question	Altered Intercellular Communication	Physical activity is an important tool used by patients with rheumatoid arthritis (RA) in order to reduce inflammation and pain as well as preserve and improve function.	10633529
Retroperitoneal fibrosis, Hyperparathyroidism, Primary	Altered Intercellular Communication	Primary hyperparathyroidism is a hormonal disease that is more and more frequent and is often manifested exclusively by an increase in calcium levels in the serum.	10633839
Inflammation, Villitis, Decidual endometritis, Chorioamnionitis, Funisitis (disorder)	Altered Intercellular Communication	Placental membrane inflammation (chorioamnionitis and funisitis), and placental villous inflammation (villitis, intervillitis, and deciduitis) were diagnosed by histopathology.	10634200
Inflammation, Rupture	Altered Intercellular Communication	Placental villous inflammation and artificial rupture of membranes did not increase transmission rates and cesarean section was associated with a nonsignificant reduction of risk (OR, 0.70; 95% CI 0.24-2.06).	10634200
Inflammation, Chlamydia, Coronary Artery Disease	Altered Intercellular Communication	Seropositivity to chlamydial lipopolysaccharide and Chlamydia pneumoniae, systemic inflammation and stable coronary artery disease: negative results of a case-control study.	10636268
Atherogenesis, Inflammation, Coronary Arteriosclerosis, Communicable Diseases	Altered Intercellular Communication	The potential contribution of CP to atherogenesis is still a matter of debate, and inflammation has been suggested to represent the link between infection and atherosclerotic disease.	10636268
Inflammatory abnormality of the eye	Altered Intercellular Communication	The spectrum of ocular inflammation caused by euphorbia plant sap.	10636407
Inflammatory abnormality of the eye	Altered Intercellular Communication	To report the spectrum of clinical findings in patients with ocular inflammation caused by plant sap from Euphorbia species.	10636407
Inflammation, Neoplasms, Urinary tract infection	Altered Intercellular Communication	The present results demonstrate that UTI can be detected in the cerebrospinal fluid, and suggest that cerebrospinal UTI increases in patients with a brain tumor or inflammation and is not affected by systemic UTI.	10636617
Inflammation, Arteritis	Altered Intercellular Communication	Heterozygotes do not die from arteritis within a year of birth but do develop small lesions, which suggests that a reduced level of IL-1ra is insufficient to fully control inflammation in arteries.	10637274
Inflammation, Virus Diseases	Altered Intercellular Communication	This finding, together with the spectacular response to corticosteroids would support the diagnosis of inflammation limited to the motor fibres, probably due to a viral infection.	10637871
Inflammation, Thrombosis	Altered Intercellular Communication	Antibiotic treatment was started and debridement performed; histopathology showed acute inflammation and thrombosis of the epidermis and dermis.	10638358
Inflammation	Altered Intercellular Communication	It allows good macroscopic evaluation of synovial inflammation and selective sampling of the synovial membrane.	10638766
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Although it is presumed that exacerbations of chronic obstructive pulmonary disease (COPD) are associated with increased airway inflammation, there is little information available on inflammatory markers during an exacerbation and the relationship with severity or time course of recovery.	10639527
Refractory anemias, Pain Distress Question, Inflammation, Congenital Abnormality	Altered Intercellular Communication	JP education aims to enable people with RA to reduce pain, inflammation, joint stress and reduce risks of deformity through using assistive devices and alternative movement patterns of affected joints to perform everyday activities.	10640116
Inflammation, Hyperemia	Altered Intercellular Communication	In 5 cases total, hyperemia was the only sonographic finding of inflammation.	10641002
Inflammation	Altered Intercellular Communication	Mostly the inflammation occurs unilateral, only in 10% of all cases both kidneys are affected.	10641513
Inflammation, Chronic pyelonephritis, Hyperoxaluria, Hypercalciuria	Altered Intercellular Communication	The exposure of the lumbar region to interference currents in combination with radon baths conducted in 37 patients with chronic pyelonephritis inhibited activity of the inflammation, hypercalciuria and hyperoxaluria, improved function of the kidneys.	10641544
Inflammation, Atherosclerosis	Altered Intercellular Communication	In conclusion, atherosclerosis alters carotid artery ACE production, increasing transcription and translation within regions of plaque inflammation.	10642324
Inflammation, Atherosclerosis	Altered Intercellular Communication	These data provide another important mechanism by which inflammation associated with increased ACE expression may contribute to the progression of atherosclerosis.	10642324
Inflammation, Lesion of liver	Altered Intercellular Communication	Based on the present results, as well as on evidence from previous studies of liver lesions, oligoclonal non-neoplastic B cell proliferation in the course of chronic infection-related inflammation appears to be the key feature of type II MC.	10643704
Inflammatory infiltrate	Altered Intercellular Communication	Cell adhesion molecules in the development of inflammatory infiltrates in giant cell arteritis: inflammation-induced angiogenesis as the preferential site of leukocyte-endothelial cell interactions.	10643715
Retinal Detachment, Intraocular inflammation, Retinal Perforations	Altered Intercellular Communication	Attacks of active ocular toxoplasmosis preceding the retinal detachment or retinal breaks were characterized by severe intraocular inflammation.	10647716
Myopia, Intraocular inflammation, Ocular Toxoplasmosis	Altered Intercellular Communication	Careful retinal examination in ocular toxoplasmosis is warranted, especially in patients with myopia and severe intraocular inflammation.	10647716
Inflammation	Altered Intercellular Communication	However, in patients with late onset and advanced disease our results indicate that the A/A type may be associated with additional inflammation different from that seen in carriers of variant alleles.	10648014
Refractory anemias, Inflammation	Altered Intercellular Communication	A highly significant association between inflammatory variables and radiographic outcome could be observed, indicating that the degree of inflammation is important for the development of destructive joint damage in RA.	10648017
Inflammation, Sinusitis	Altered Intercellular Communication	Chronic sinusitis is a common disease characterized by persistent inflammation of the nasal and paranasal sinus mucosa.	10648069
Inflammation Mediators, Cerebral Ischemia	Altered Intercellular Communication	These results indicate that prostanoid synthesis is up-regulated in microglia during chronic cerebral ischemia, and that these cells may be involved in tissue repair or inflammation-mediated cell responses.	10651024
Nasal inflammation	Altered Intercellular Communication	It is therefore possible to detect nasal inflammation in ML patients through QNCs, which may indicate extension of mucosal involvement, providing an objective parameter to monitor therapy.	10651420
Inflammation	Altered Intercellular Communication	Transbronchial biopsies showed inflammation and hemosiderin-laden macrophages; no specific diagnosis was established.	10653069
Fibrosis Assessment, Chronic inflammation	Altered Intercellular Communication	Histopathologic studies revealed herniated mucosa through the muscular layer associated with chronic inflammation and marked fibrosis.	10653074
Sepsis, Inflammation	Altered Intercellular Communication	Experiments performed in TNFalpha knockout mice allowed a direct evaluation of the part played by MIF in sepsis in the absence of this pivotal cytokine of inflammation.	10655104
Inflammatory abnormality of the eye	Altered Intercellular Communication	There was no indication of increased postoperative ocular inflammation, intraocular pressure change, or endothelial cell loss.	10655193
Crohn Disease, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The retrieval of new cases of ulcerative colitis (UC) and Crohn's disease (CD) was based on a monthly review of all small and large intestinal tissue specimens with any type of inflammation submitted to all three departments of pathology in Iceland.	10656207
Hepatitis, Drug-Induced, Inflammation, Portal inflammation	Altered Intercellular Communication	Liver histology showed marked portal inflammation with lymphocytes, monocytes and eosinophils, associated with lobular inflammation (indicative of a histological pattern consistent with drug-induced hepatitis).	10656221
Acute viral hepatitis	Altered Intercellular Communication	In conclusion, this case strongly suggests that gliclazide can induce acute icteric liver necro-inflammation which may be misdiagnosed clinically as acute viral hepatitis.	10656221
Granulomatous inflammation	Altered Intercellular Communication	Histologic examination revealed widespread granulomatous inflammation and characteristic broad, non-septate hyphae with right-angle branching in the dermis.	10659506
Inflammation, Obstruction	Altered Intercellular Communication	Only one patient was not treated surgically because he had no evidence of gut obstruction and inflammation.	10659538
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	No excessive inflammation or fibrosis at the host-device interface was noted.	10660184
Inflammation, Hypoxia	Altered Intercellular Communication	Inflammation and hypoxia are frequently associated, but their interaction is poorly understood.	10660846
Uremia, Inflammation	Altered Intercellular Communication	We conclude that ZnPP untimely parallels a change in iron balance in only a proportion of uremic people, in as much as confounding factors, such as chronic inflammation and uremia in itself may obscure its relationship with iron status.	10661481
Inflammation	Altered Intercellular Communication	It may also play an important role in acute inflammation and tissue repair.	10661682
Keratitis, Infection, Keratitis, Herpetic	Altered Intercellular Communication	When penetrating keratoplasty is indicated, special attention should be given to (1) the compliance of the patient, (2) sufficient treatment of herpes keratitis or other infections, (3) adequate immunosuppression in autoimmune corneal inflammation, (4) double running continuous sutures as primary suture with sometimes additional single sutures to stabilize the graft, and (5) surgery in time.	10663783
Inflammation, Thromboembolism	Altered Intercellular Communication	In addition, findings of intimal inflammation, intact media and absence of medial calcification were demonstrated to be common in both TAO and thromboembolism.	10664163
Three-dimensional, Inflammation	Altered Intercellular Communication	Quantitative analysis of three-dimensional complexity and connectivity changes in trabecular microarchitecture in relation to aging, menopause, and inflammation.	10664426
Chronic inflammation, Osteopenia	Altered Intercellular Communication	There are several types of bone loss besides that associated with normal aging, eg, that associated with the menopause, and that associated with chronic inflammation, and these are considered to be caused by different mechanisms.	10664426
senile	Altered Intercellular Communication	Thirty-five Fisher 344 rats were divided into five groups (control, young, senile, ovariectomized [OVX], and inflammation-mediated osteopenia [IMO]) and distal femoral metaphysis was scanned by Micro-CT to nondestructively acquire a 3-D CT stack consisting of 50 consecutive slices at a spatial resolution of 26 microm.	10664426
Inflammation	Altered Intercellular Communication	Historical and morphometric data were obtained characterizing different stages of chronic inflammation in periulcerative region.	10664812
Neurogenic Inflammation, CP 122288	Altered Intercellular Communication	No acute antimigraine efficacy of CP-122,288, a highly potent inhibitor of neurogenic inflammation: results of two randomized, double-blind, placebo-controlled clinical trials.	10665496
Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology characterized by inflammation in various organ systems, including lymph nodes, due to the production of antinuclear antibodies.	10667163
Parkinson Disease, palladium	Altered Intercellular Communication	Parkinson's disease (PD) is characterized by major alterations of neurotransmitter activity due to damage of the substantia nigra.	10668930
Inflammation, Structure of left optic nerve	Altered Intercellular Communication	Idiopathic sclerotic inflammation of the orbit with left optic nerve compression in a patient with multifocal fibrosclerosis.	10669249
Orbital Pseudotumor	Altered Intercellular Communication	We present the MR imaging findings in a 43-year-old male patient with bilateral idiopathic sclerosing inflammation of the orbit.	10669249
Tissue damage, Inflammation	Altered Intercellular Communication	Intercellular adhesion molecule 1 (ICAM-1) is a marker of inflammation and tissue damage.	10669322
Inflammation	Altered Intercellular Communication	It is thought that autoantibodies against some of these antigens play a role in causing acute inflammation of the respiratory epithelium.	10669715
Inflammation, Sinusitis, Nasopharynx	Altered Intercellular Communication	Seven patients had latent chronic sinusitis, 5 had nasopharyngeal lesions, such as Tornwaldt's cyst and inflammation, 3 had "old man's PND", 2 had "reflux PND", and 2 had polyps around the sphenoid ostium.	10670030
Inflammation	Altered Intercellular Communication	If deposited on the surface of a bladder with chronic inflammation or some other previous lesion, may produce an alkaline encrusted cystitis, now a rare condition.	10670133
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	The clearance of apoptotic cells is crucial to avoid chronic inflammation and autoimmunity.	10670577
Degenerative polyarthritis, Rheumatoid Arthritis	Altered Intercellular Communication	The increase of parathyroid hormone-related peptide and cytokine levels in synovial fluid of elderly rheumatoid arthritis and osteoarthritis.	10670749
Inflammation, immunoglobulin A	Altered Intercellular Communication	Social class was inversely associated with secondary immune response parameters (IgG, IgA), whereas indicators of primary immune reactions and inflammation (IgM, C3c, leukocytes) were not related to social status.	10674286
Orbital Pseudotumor	Altered Intercellular Communication	The patient was subsequently diagnosed with orbital pseudotumor after computed tomography scan revealed inflammation of orbital structures bilaterally.	10674540
Alzheimers Disease", Inflammation	Altered Intercellular Communication	Increased plasma levels of interleukin-1, interleukin-6 and alpha-1-antichymotrypsin in patients with Alzheimer's disease: peripheral inflammation or signals from the brain?	10674995
Inflammation, Data types - Address	Altered Intercellular Communication	Detection of these molecules might be used for monitoring the progression of brain inflammation associated with AD.	10674995
Inflammation, Fibrosis Assessment, Androgenetic Alopecia, Alopecia	Altered Intercellular Communication	Some patients with androgenetic alopecia might have additional clinical and histological features of inflammation and fibrosis limited to the area of androgenetic hair loss.	10677097
Inflammation	Altered Intercellular Communication	These results suggest that circulatory neutrophils after cardiac surgery with CPB have enhanced responsiveness and are predisposed to systemic inflammation.	10677155
Delirium	Altered Intercellular Communication	Decreased Trp and increased Phe availability may give rise to an imbalance in cerebral neurotransmitters and thus contribute to delirium.	10678514
Airway structure, Fibrosis Assessment	Altered Intercellular Communication	Cystic fibrosis (CF) is associated with a neutrophil dominated airway inflammation.	10678636
Airway structure	Altered Intercellular Communication	Therefore, neutrophil dominated airway inflammation is more pronounced in the first, mainly bronchial, bronchoalveolar lavage sample suggesting that sequential analysis of bronchoalveolar lavage fluid may have a higher sensitivity to detect early inflammatory changes in CF patients.	10678636
Stenosis of tracheobronchial tree, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Computed tomography of the chest revealed extensive nodular tracheobronchial stenosis, that was accompanied by severe mucosal inflammation at bronchoscopy.	10678648
Inflammation, Stenosis of tracheobronchial tree	Altered Intercellular Communication	High-dose oral steroids diminished the mucosal inflammation, but had limited efficacy on the underlying tracheobronchial stenosis.	10678648
Degenerative polyarthritis, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	In the present study, we hypothesized that elevated in the joints of rheumatoid arthritis, but not osteoarthritis, patients, IL-15 may exert its proinflammatory properties via the induction of IL-17, a cytokine known to stimulate synoviocytes to release several mediators of inflammation including IL-6, IL-8, GM-CSF and PGE2.	10679127
Inflammation	Altered Intercellular Communication	Of 80 patients with a positive serological test and negative histological evaluation for H. pylori, chronic antral inflammation was found in 70 patients (87%).	10679585
Inflammation	Altered Intercellular Communication	In 46 patients with both negative serological test and H. pylori negative test according to histology, only 13 (28%) had chronic antral inflammation.	10679585
Inflammation, Psoriasis, Inflammatory dermatosis	Altered Intercellular Communication	Psoriasis is a chronic inflammatory skin disease, and besides inflammation, disturbed differentiation and hyperproliferation are its hallmarks.	10679742
Granulomatous inflammation, Malignant Neoplasms	Altered Intercellular Communication	The prognostic significance of the association of granulomatous inflammation and malignancy is reviewed.	10681617
Inflammation	Altered Intercellular Communication	After two initial conjunctival biopsies that showed only chronic inflammation, a third biopsy revealed the presence of amyloid in the substantia propria of the conjunctiva.	10682979
Inflammation, Thrombosis	Altered Intercellular Communication	Antibodies to TM may be an important risk factor for inflammation and thrombosis in these patients.	10685802
Inflammation	Altered Intercellular Communication	Our results suggest that preexisting chronic inflammation plays an important pathogenetic role in the PVNS disease process.	10685815
Inflammation, Hemorrhage	Altered Intercellular Communication	Chronic inflammation increases the risk of articular bleeding and probably deranges the iron processing capacity of local synovial macrophages.	10685815
Inflammation	Altered Intercellular Communication	MRI was significantly better than scintigraphy at detecting the presence and assessing the extent of extraosseous inflammation.	10687907
Inflammation, Elastosis perforans serpiginosa	Altered Intercellular Communication	However, although this association does not directly prove the significance of VB3 in those patients from whom no EPS can be obtained, we suggest this method be taken into account as an indirect indicator in the diagnosis of inflammation.	10688073
Urethritis, Chronic prostatitis	Altered Intercellular Communication	Detecting urethral and prostatic inflammation in patients with chronic prostatitis.	10688076
Urethritis	Altered Intercellular Communication	Diagnosis of urethral and prostatic inflammation can represent a challenge.	10688076
Inflammation	Altered Intercellular Communication	We compare the accuracy of diagnostic methods for detecting inflammation in lower urinary specimens/samples.	10688076
prostatitis, Elastosis perforans serpiginosa	Altered Intercellular Communication	Of 83 subjects with prostatic inflammation, the EPS detected 63 (76%) and the VB3 detected 68 (82%).	10688076
Urethritis	Altered Intercellular Communication	VB1 or VB2 examinations had low sensitivity for detecting urethral inflammation.	10688076
Elastosis perforans serpiginosa, prostatitis	Altered Intercellular Communication	Examining both the EPS and VB3 proved best for detecting prostatic fluid inflammation.	10688076
Urethritis	Altered Intercellular Communication	Combining the urethral smear with lower urinary tract localization ("four-glass test") represents an optimal approach for detecting urethral and prostatic inflammation.	10688076
Enterocolitis, Neutropenic, Inflammation, Malignant Neoplasms, Leukopenia	Altered Intercellular Communication	Neutropenic enterocolitis is an acute, life-threatening inflammation of the small and large bowel, often seen in children with malignancies during periods of prolonged or severe neutropenia.	10689720
Inflammation	Altered Intercellular Communication	To compare the postoperative inflammation after phacoemulsification followed by intraocular lens (IOL) implantation by means of sclerocorneal versus clear corneal tunnel incision.	10690818
Inflammatory disease of mucous membrane	Altered Intercellular Communication	This seems to be attenuated after eradication and resolution of mucosal inflammation.	10691918
Inflammation	Altered Intercellular Communication	L-selectin (CD62L) is a cell adhesion molecule which plays a key role in the initiation of leucocyte migration from blood vessels to sites of local inflammation.	10692053
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Skin biopsies from 40 patients demonstrating a band-like lymphocytic infiltrate with concomitant granulomatous inflammation were encountered over 4 years.	10692062
Necrotizing granulomatous inflammation, Refractory anemias, Diabetes Mellitus, Rheumatoid Arthritis, Hepatitis C, Thyroiditis, Crohn Disease	Altered Intercellular Communication	Over one-third of patients with drug-related eruptions had other medical illnesses associated with cutaneous granulomatous inflammation, namely rheumatoid arthritis (RA), Crohn's disease, hepatitis C, diabetes mellitus, and thyroiditis.	10692062
Inflammation, Malnutrition, Hypoalbuminemia	Altered Intercellular Communication	Although hypoalbuminemia has been attributed to malnutrition, evidence of inflammation (C-reactive protein [CRP] and cytokine levels) has recently been recognized to predict albumin concentration in dialysis patients.	10692273
Inflammation, Leprosy, Numbness, Absence of sensation	Altered Intercellular Communication	While sensory loss in leprosy skin is the consequence of invasion by M. leprae of Schwann cells related to unmyelinated fibres, early loss of cutaneous pain sensation, even in the presence of nerve fibres and inflammation, is a hallmark of leprosy, and requires explanation.	10692623
Hypersensitivity	Altered Intercellular Communication	However, NGF-immunoreactivity in basal keratinocytes, and intra-epidermal PGP 9.5-positive nerve fibres, were reduced in both sites compared to non-leprosy controls, as were nerve fibres positive for the sensory neurone specific sodium channel SNS/PN3, which is regulated by NGF, and may mediate inflammation-induced hypersensitivity.	10692623
Inflammation, Leprosy, Cutaneous, Absence of sensation	Altered Intercellular Communication	We conclude that decreased NGF- and SNS/PN3-immunoreactivity, and loss of intra-epidermal innervation, may be found without sensory loss on quantitative testing in clinically-unaffected skin in leprosy; this appears to be a sub-clinical change, and may explain the lack of cutaneous pain with inflammation.	10692623
Inflammation, Malignant neoplasm of gastrointestinal tract	Altered Intercellular Communication	Longitudinal study of weight, appetite, performance status, and inflammation in advanced gastrointestinal cancer.	10693165
Inflammation, Periodontal Route of Administration	Altered Intercellular Communication	These findings suggested that GCF IL-6 levels were significantly higher in the area of inflammation and periodontal destruction locally.	10693291
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The effects of interferon-beta treatment of synovial inflammation and expression of metalloproteinases in patients with rheumatoid arthritis.	10693865
Sepsis	Altered Intercellular Communication	Inflammation-induced systemic proteolysis of inter-alpha-inhibitor in plasma from patients with sepsis.	10695665
Inflammation	Altered Intercellular Communication	Rate of clearance of inflammation was better in the steroid plus group (40 +/- 15.5 vs 55 +/- 8.6 days).	10696322
Inflammation, Fungal endophthalmitis	Altered Intercellular Communication	The results of our retrospective study suggest that steroids may be beneficial in promoting faster clearance of inflammation in fungal endophthalmitis.	10696322
Retinitis	Altered Intercellular Communication	Angiographic findings recorded on videotapes were evaluated, and the relation of ICG angiographic findings with systemic activity and the extent of retinal inflammation was analyzed.	10696741
Alveolar, Inflammation, Diffuse alveolar hemorrhage, Hamman-Rich syndrome	Altered Intercellular Communication	Post mortem examination demonstrated fibrosing alveolitis and alveolar bleeding in Patient 1, and an immune complex deposition-induced alveolocapillary inflammation with alveolar haemorrhage in Patient 2.	10697987
Inflammation, Corneal stromal opacities	Altered Intercellular Communication	The enrollment criteria were: phakic eye, no history of intraocular surgeries or inflammation, and no corneal opacification.	10698026
Malignant Neoplasms	Altered Intercellular Communication	In conclusion, microsatellite alterations in urine are indicators not only of malignancy but also of inflammatory conditions.	10699938
Necrotizing granulomatous inflammation	Altered Intercellular Communication	However, fine needle aspiration has in this study proved to be a simple technique to demonstrate inflammation granulomas and AFB from these involved nerves in 18 of the 27 cases suspected to have PNL.	10700918
Inflammation	Altered Intercellular Communication	Cyclooxygenase (COX)-2 is involved in chronic inflammation and epithelial cell growth.	10702199
Hormone abnormality, Overweight	Altered Intercellular Communication	hormonal disorders) may be involved in the overweight patients.	10702761
Cataract, Inflammation	Altered Intercellular Communication	To determine the safety and efficacy of an intraocular dexamethasone drug delivery system (Surodex) in the treatment of inflammation following cataract surgery.	10703128
Inflammation, Vasculitis, CTCAE, Ischemia	Altered Intercellular Communication	The diagnoses were classified into three categories: inflammation, vasculitis or ischaemia.	10703473
Inflammation, Vasculitis, CTCAE, Intestinal Diseases, Ischemia	Altered Intercellular Communication	Bowel wall thickening was observed in the bowel diseases demonstrating inflammation, vasculitis and ischaemia.	10703473
Ischemia, Inflammation	Altered Intercellular Communication	Patients with ischaemia were significantly older than those with inflammation.	10703473
Ischemia, Inflammation	Altered Intercellular Communication	The absence of a colour Doppler flow and of an arterial signal suggested ischaemia, while in younger patients, an abundant colour Doppler flow and a stratified echotexture suggested inflammation.	10703473
Airway structure	Altered Intercellular Communication	Asthma is characterized by airway inflammation, which can be now assessed by the analysis of induced sputum.	10704078
Inflammation, Asthma	Altered Intercellular Communication	Our findings indicated that in asthmatic patients, activated lymphocytes accumulate in the bronchi; because of their prolonged survival that maintains inflammation.	10704078
Dacryoadenitis, Epstein-Barr Virus Infections	Altered Intercellular Communication	To describe the clinical features of lacrimal gland inflammation associated with Epstein-Barr virus infection.	10704555
Cataract, Inflammation	Altered Intercellular Communication	A 40-year-old woman developed recurrence of inflammation after extracapsular cataract extraction with intraocular lens (IOL) implantation.	10704562
Inflammation, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	The strong relationships with fibrinogen and HDL-cholesterol suggest a role for inflammation throughout life in the development of atherosclerosis and cardiovascular disease.	10704625
Inflammation, Alveolar Septum, Blood Circulation	Altered Intercellular Communication	These findings indicated that postmortem elevation of serum SP-A levels was associated with alveolar septal damage due to inflammation, mechanical and physical stresses, which caused leakage of SP-A into the bloodstream.	10704815
Biliary calculi, Gallbladder	Altered Intercellular Communication	To characterize the response of gallbladder muscle strips, from patients with acalculous biliary pain, to hormonal and muscarinic stimulation and to compare these with strips from gallstone patients and normal controls.	10705179
Airway structure, Asthma	Altered Intercellular Communication	Because eosinophilic airway inflammation is a characteristic feature of bronchial asthma, the treatment of airway inflammation is important in the management of asthma.	10705222
Airway structure, Asthma, Eosinophilic inflammation	Altered Intercellular Communication	These findings suggest that theophylline reduces airway inflammation and the severity of asthma, presumably via suppression of both eosinophil activity and subsequent eosinophil infiltration of the airways.	10705222
Inflammation, Lung diseases, physiopathological	Altered Intercellular Communication	These findings suggest that small airway dysfunction in MAI infection without predisposing lung disease is related to the inflammation probably related to the neutrophil.	10705262
Inflammation, Bronchiectasis, Idiopathic Pulmonary Fibrosis, Pneumonia	Altered Intercellular Communication	Neutrophil inflammation and activation in bronchiectasis: comparison with pneumonia and idiopathic pulmonary fibrosis.	10705263
Bronchiectasis, Idiopathic Pulmonary Fibrosis, Pneumonitis, Pneumonia	Altered Intercellular Communication	Pulmonary inflammation in bronchiectasis, pneumonia and idiopathic pulmonary fibrosis (IPF) is dominated by neutrophils.	10705263
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Inhaled corticosteroids may reduce neutrophilic inflammation in patients with stable chronic obstructive pulmonary disease.	10705266
ARCN1 gene, Inflammation	Altered Intercellular Communication	These data suggest that neutrophilic inflammation in sputum may be decreased by inhaled corticosteroids in clinically stable COPD patients.	10705266
Airway structure	Altered Intercellular Communication	This paper explores the possibility of airway inflammation in cases of this kind.	10705711
Hypothalamic Dysfunction Syndromes	Altered Intercellular Communication	The pattern of hormonal responsiveness suggests that CH encompasses findings typical of primary anterior pituitary disease and those of hypothalamic dysfunction.	10705718
Bronchitis, Exacerbation	Altered Intercellular Communication	Bronchial inflammation in acute bacterial exacerbations of chronic bronchitis: the role of leukotriene B4.	10706491
Inflammation, Kidney Diseases, Platelet aggregation test result	Altered Intercellular Communication	Further adjustment for factors related to renal disease, nutrition, platelet aggregation, inflammation, use of angiotensin-converting enzyme inhibitors, and hemostasis factors attenuated the albumin-CHD relation only slightly.	10707915
Inflammation, Dental Plaque	Altered Intercellular Communication	Gingival inflammation and plaque were also strongly associated with GH (P<0.0003).	10708105
Gingivitis, Inflammation	Altered Intercellular Communication	In multivariate analysis, however, the last recorded dose of CsA (P<0.0001), presence of local gingival inflammation (P<0.0001), and gingivitis (P<0.003) were the independent predictors of the extent and severity of GH.	10708105
Inflammation	Altered Intercellular Communication	Inter-site variation in the extent and severity of the disease is related to local gingival inflammation.	10708105
Communicable Diseases, Inflammation	Altered Intercellular Communication	The overt infection clinically (pus group) of the membrane-allograft treated sites is associated with a significantly elevated BAS of rod-shaped bacteria, and may be closely related to the occurrence of its adverse early healing responses (inflammation, pus formation, fewer fibroblasts and greater accumulation of leukocytes).	10709342
Airway structure, Rhinovirus infection	Altered Intercellular Communication	Glucocorticoid may modulate airway inflammation via reducing the production of proinflammatory cytokines and ICAM-1 induced by rhinovirus infection.	10710529
Inflammation, Earache, Ear discharge	Altered Intercellular Communication	The overall response expressed as an improvement or cure of otalgia, otorrhea and middle ear mucosal inflammation was recorded.	10710871
Inflammation	Altered Intercellular Communication	These results suggest that various periodontopathogens can colonize in the very early childhood of DS patients and maturation of subgingival components, including P. gingivalis, plays an important role in the initiation of gingival inflammation.	10711615
Inflammation, Clinically significant macular edema, Retinal Diseases, Edema	Altered Intercellular Communication	Logarithm of minimum angle of resolution visual acuity (logMAR VA), incidence of clinically significant macular edema (CSME), retinopathy progression, indices of anterior segment inflammation, and incidence of capsulotomy.	10711881
Intracapsular cataract extraction, Acute inflammation, Diabetes Mellitus	Altered Intercellular Communication	Phacoemulsification is associated with better postoperative VA, less postoperative inflammation, and less need for capsulotomy than extracapsular cataract surgery in patients with diabetes.	10711881
Cranial nerve palsies, Orbital Pseudotumor	Altered Intercellular Communication	Rhino-orbital-cerebral mucormycosis should be considered in all patients with orbital inflammation associated with multiple cranial nerve palsies and retinal or orbital infarction, regardless of their immunologic status.	10711895
Retinal Vein Occlusion, Inflammatory abnormality of the eye, Disorder of eye, Uveitis	Altered Intercellular Communication	Four patients presented with a neuro-ophthalmologic disorder, five had external ocular inflammation, 10 patients had uveitis, and one had branch retinal vein occlusion.	10711899
Photophobia, Inflammatory abnormality of the eye, Disorder of eye, Uveitis	Altered Intercellular Communication	Two patients with a neuro-ophthalmologic disorder and one with external ocular inflammation experienced severe photophobia, whereas the main reported symptom of the patients with uveitis was decreased visual acuity.	10711899
Airway structure	Altered Intercellular Communication	However, this approach may mask underlying airway inflammation.	10712354
Inflammation, Nesidioblastosis, Bronchitis	Altered Intercellular Communication	Goblet cell hyperplasia and epithelial inflammation in peripheral airways of smokers with both symptoms of chronic bronchitis and chronic airflow limitation.	10712357
ARCN1 gene, Inflammation	Altered Intercellular Communication	A central feature in the pathogenesis of COPD is the inflammation coexisting with an abnormal protease/antiprotease balance.	10712992
Behcet Syndrome	Altered Intercellular Communication	Behcet's disease (BD) is a chronic inflammatory condition involving several organs, such as skin, mucous membrane, eye, joint, intestine, lung and central nervous system.	10714100
Granulomatous inflammation	Altered Intercellular Communication	Biopsies showed granulomatous inflammation, but no microorganisms were detected.	10714126
Inflammation, Abnormality of head blood vessel, Necrosis	Altered Intercellular Communication	Necrosis of the cord was found in biopsy material from one patient and postmortem pathology in another case, but inflammation and blood vessel abnormalities were absent.	10714661
Inflammation, Epiploic appendagitis	Altered Intercellular Communication	A 1-4-cm, oval, fatty pericolic lesion with surrounding mesenteric inflammation is diagnostic of epiploic appendagitis.	10715339
Diverticulitis, Diverticulum	Altered Intercellular Communication	The key to distinguishing diverticulitis from other inflammatory conditions of the colon is the presence of diverticula in the involved segment.	10715339
Inflammation, Injury of liver, Inflammatory disorder	Altered Intercellular Communication	The elevation of TFPI:Ag and TFPI:A in hepatic inflammatory diseases is an indication of inflammation, and hepatic tissue injury in broad, the lower level of AT-III liver secretions.	10715793
Filarial Elephantiases, Tumor necrosis, Inflammation, Chronic disease	Altered Intercellular Communication	Pre-treatment levels of interleukin (IL)-6 and soluble tumour necrosis factor receptor 75 (sTNF-R75) were higher in elephantiasis patients compared to microfilaraemics and endemic normals, indicating the presence of an ongoing inflammation in patients with chronic disease.	10717762
Inflammation, Arterial Hypervascularization, Edema	Altered Intercellular Communication	Many of the false-positive results were due to inflammation, hypervascularization, and edema.	10718421
Granulomatous inflammation	Altered Intercellular Communication	Tonsils are uncommonly affected by granulomatous inflammation, often with an obscure cause.	10718441
Necrotizing granulomatous inflammation	Altered Intercellular Communication	This study attempts to elucidate the nature of tonsillar granulomatous inflammation.	10718441
Inflammation, Pancreatitis	Altered Intercellular Communication	Inflammation and oxidative stress are believed to be important in the development of the systemic complications of acute pancreatitis.	10718798
Adenoma, Blood Circulation	Altered Intercellular Communication	Surprisingly, circulating epithelial cells were detected in 3/30 (10%) patients resected for adenoma, and in 4/34 (12%) patients resected for benign inflammatory conditions, suggesting that cells from nonmalignant colonic epithelium may also gain entry into the bloodstream in the presence of bowel pathology.	10719724
Inflammation, Liver Dysfunction, Jaundice, Obstructive	Altered Intercellular Communication	These results suggest that systemic inflammation and the hepatic dysfunction caused by obstructive jaundice cause an increase in the plasma concentrations of hHGF.	10719751
Inflammation	Altered Intercellular Communication	Portal inflammation was mild, but interphase activity was definite and cholangiolar proliferation was prominent.	10719821
Herpes Simplex Infections, Keratoconjunctivitis, Inflammation	Altered Intercellular Communication	Two subjects with epidemic keratoconjunctivitis were treated for 7-10 days and 1 subject with herpes simplex blepharitis for 3 days with no rapid improvement but probable mitigation of inflammation.	10720913
Inflammation, Hemorrhage, Obstruction, Hypoxia	Altered Intercellular Communication	Since the lipid droplets were seen also in cells other than histiocytes, it appears that these changes are secondary to a common mechanism, comprising factors such as obstruction, hemorrhage, inflammation, and local hypoxia.	10721150
Communicable Diseases, Inflammation	Altered Intercellular Communication	Bleb-related infection was classified as blebitis when a mucopurulent infiltrate was identified within the bleb and associated with mild to moderate anterior segment inflammation.	10721955
Inflammation	Altered Intercellular Communication	The middle lobe and lingula are predisposed to chronic inflammation because of their particular anatomic structures.	10722445
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Inflammation after acute myocardial infarction is supposed to be involved in enhanced HGF production.	10722550
Airway structure, Asthma	Altered Intercellular Communication	The pulmonary antioxidant glutathione may limit airway inflammation in asthma.	10722764
Inflammation, Giant Cell Arteritis, Musculoskeletal Pain	Altered Intercellular Communication	Positron emission tomography in giant cell arteritis and polymyalgia rheumatica: evidence for inflammation of the aortic arch.	10723979
Inflammation, Infectious agent	Altered Intercellular Communication	The presence of the foreskin may promote inflammation by a koebnerization phenomenon, or the presence of infectious agents, as yet unidentified, may induce inflammation.	10724196
Aplasia Cutis Congenita	Altered Intercellular Communication	Such a cell to cell communication seems to be impossible in patients with aplasia cutis congenita, as the dermal-epidermal unit is not developed.	10725814
Inflammation, Sarcoidosis	Altered Intercellular Communication	The histological diagnosis was non-necrotizing granulomatous inflammation, consistent with sarcoidosis.	10725958
Inflammation, Swelling	Altered Intercellular Communication	Four weeks later he was admitted again with a major localized painful swelling of the soft tissues, whereas the clinical examination revealed no further local or systemic signs of inflammation.	10726174
Inflammation, Necrosis	Altered Intercellular Communication	Necroinflammation was significantly diminished in the second biopsy due to a lesser necrosis and inflammation of the lobules.	10726374
Inflammation, Thickened	Altered Intercellular Communication	The meconium group's bowel showed serosal thickening, inflammation, focal fibrin, and collagen deposits.	10726689
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Monocyte chemoattractant protein 1, interleukin 8, and chronic airways inflammation in COPD.	10727989
ARCN1 gene, Inflammation, Chronic Airflow Obstruction	Altered Intercellular Communication	Hallmarks of COPD include chronic airflow obstruction and chronic inflammation in the airway walls or alveolar septa.	10727989
Inflammation, Cardio-Renal Syndrome, Coronary Arteriosclerosis	Altered Intercellular Communication	Multiple studies support a role for inflammation in the pathogenesis of coronary atherosclerosis and unstable cardiac syndromes.	10728019
Inflammation, Cardio-Renal Syndrome, Coronary Arteriosclerosis	Altered Intercellular Communication	Multiple studies support a role for inflammation in the pathogenesis of coronary atherosclerosis and unstable cardiac syndromes.	10728019
Inflammation, Arthritis	Altered Intercellular Communication	The results indicate that bacterial DNA and bacterial cell wall constituents are retained in the joints of some patients with arthritis, where they might enhance synovial inflammation.	10728753
Inflammation, Coronary heart disease	Altered Intercellular Communication	Relation of inflammation to vascular function in patients with coronary heart disease.	10729391
Inflammation, Thrombosis, Endothelial dysfunction	Altered Intercellular Communication	Inflammation may in turn induce endothelial dysfunction and thus increase the risk of atherothrombosis.	10729391
Inflammation, Atherosclerosis, Communicable Diseases, Coronary heart disease, Endothelial dysfunction	Altered Intercellular Communication	It is possible that endothelial dysfunction in coronary heart disease patients is related to the chronic inflammation or infection coexisting with atherosclerosis.	10729391
Inflammation, histiocytic	Altered Intercellular Communication	Xanthogranulomatous inflammation in the female genital tract is rare and characterized by a massive infiltration of the tissue by lipid containing histiocytic cells, together with lymphocytes and plasma cells.	10730149
Inflammation	Altered Intercellular Communication	We report a new case of Xanthogranulomatous inflammation of the female genital tract.	10730149
Residue on Palate, Inflammation, Glossitis	Altered Intercellular Communication	In the experimental group the severity of the inflammation of the palate decreased (P = 0.005) as well as the prevalence of glossitis (P = 0.005).	10730723
Inflammation, Eczema	Altered Intercellular Communication	The atopic inflammation in the skin, genetics and treatment used for eczema are possible factors that may influence the formation of melanocytic naevi.	10730765
Inflammation, Angina, Unstable	Altered Intercellular Communication	The involvement of inflammation in unstable angina is suggested by the presence of activated circulating leukocytes.	10732847
Inflammation, Angina, Unstable	Altered Intercellular Communication	Plaque inflammation in restenotic coronary lesions of patients with stable or unstable angina.	10732895
Inflammation, Angina, Unstable	Altered Intercellular Communication	To evaluate immunohistochemically various parameters of inflammation in coronary atherectomy specimens obtained from restenotic culprit lesions of patients presenting with either stable or unstable angina (UA).	10732895
Plaque, Atherosclerotic	Altered Intercellular Communication	There is no information regarding the relationship between atherosclerotic plaque inflammation and the severity of the coronary syndromes in patients with restenotic coronary lesions.	10732895
Inflammation, Acute Coronary Syndrome, Dental Plaque	Altered Intercellular Communication	These results suggested that inflammation appears to affect plaque instability in restenotic coronary lesions resulting in unstable coronary syndromes.	10732895
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	Regarding histological parameters, activity and inflammation, not atrophy or intestinal metaplasia, were significantly improved in the treatment group.	10735925
Inflammation, Injury of nose	Altered Intercellular Communication	This case suggests that the combination of basal cell injuries caused by chronic inflammation and PUVA therapy could expose BMZ components to autoreactive lymphocytes and induce LPP.	10735960
Inflammation, Squamous cell carcinoma	Altered Intercellular Communication	This may be another example of chronic inflammation of the vulval area leading to the development of squamous cell carcinoma.	10735968
Inflammation, Takayasu Arteritis	Altered Intercellular Communication	The present study demonstrates that immune inflammation is a typical feature of Takayasu's disease, and that the interactions between dendritic cells and lymphocytes may be important in the control of the immune reactions in this vascular pathology.	10737351
Inflammation, Neoplasms	Altered Intercellular Communication	Perineural inflammation, perineural tumor invasion, or both were present in 29 of the 78 tumors (37%), or 6.7% of all 434 prospectively evaluated cases.	10738219
Perineural spread, Inflammation, Neoplasms	Altered Intercellular Communication	Twenty-one of the 78 tumors (26.9%) exhibited perineural inflammation, 3 (3.8%) demonstrated perineural invasion, and 5 (6.4%) exhibited both.	10738219
Inflammation, Neoplasms	Altered Intercellular Communication	Tumors with perineural inflammation, inflammation plus tumor invasion, and invasion alone were, respectively, 138%, 149%, and 194% greater in area preoperatively than tumors without perineural involvement, and their mean defect areas after Mohs surgery were, respectively, 151%, 121%, and 605% larger than those of tumors without perineural involvement.	10738219
Inflammation, Pulmonary dirofilariasis, Carcinoma of lung	Altered Intercellular Communication	Because the pulmonary dirofilariasis is difficult to be differentiated from primary or metastatic lung carcinoma, and the inflammation exists around the nodule, the nodule should be removed surgically.	10739166
Inflammation, Myxoma of the Endocardium	Altered Intercellular Communication	Therefore, mesenchyme cells with immature phenotype in the channel play pivotal roles of inflammation and pathogenesis of cardiac myxoma.	10739905
Inflammation	Altered Intercellular Communication	Obscuring inflammation contributed to false negative diagnoses in two cases.	10740596
Pneumonitis	Altered Intercellular Communication	Pulmonary tumorlets are localized lesions of neuroendocrine cell proliferation, usually found in association with chronic pulmonary inflammation.	10740614
Airway structure, Asthma, Airway Obstruction	Altered Intercellular Communication	Assuming that bronchial reactivity could be an indirect measurement of airway inflammation, overtreatment of asthma in relationship with the classification of asthma severity of the International Guidelines could improve both airway inflammation and the prognosis of airway obstruction.	10741095
Inflammation	Altered Intercellular Communication	NRM treated sites showed less signs of post-surgical inflammation during the 1st 4 weeks of healing than did RM treated sites (p<0.05).	10743863
Communicable Diseases	Altered Intercellular Communication	In contrast, inflammations or progressive resorptions were not observed in teeth without preoperative infection of the pulp.	10743867
Tuberculosis, Pulmonary, Bronchitis	Altered Intercellular Communication	Stepwise forceps biopsy was used in 29 patients with different forms of pulmonary tuberculosis, which may ascertain the pattern of bronchial inflammation and the pathogenetic mechanisms of extension of an abnormal process to the bronchial wall, which is important in determining treatment policy.	10750423
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	We studied markers of inflammation and coagulation in thoracic aortic operations with heparin-coated circuits and standard vs reduced systemic heparinization.	10750754
Communicable Diseases, Pneumonitis	Altered Intercellular Communication	F-18 fluorodeoxyglucose chest uptake in lung inflammation and infection.	10750966
Communicable Diseases, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	F-18 fluorodeoxyglucose (FDG) may accumulate at sites of inflammation or infection, making interpretation of whole-body scans difficult in patients with cancer.	10750966
Inflammation, Primary malignant neoplasm, Infectious Lung Disorder	Altered Intercellular Communication	More than 650 whole-body positron emission tomographic (PET) scans performed to examine patients with cancer were reviewed to identify uptake in pulmonary infection or inflammation based on the appearance of F-18 FDG chest uptake, chest radiographs, computed tomography, or all of these.	10750966
Communicable Diseases, Atelectasis, Pneumonitis	Altered Intercellular Communication	In all patients, the F-18 FDG lung uptake corresponded to benign radiologic changes (infiltration, consolidation, or atelectasis), and the final diagnosis was pulmonary inflammation or infection.	10750966
Communicable Diseases, Inflammation, Neoplasms	Altered Intercellular Communication	They can be classified based on the underlying mechanism into four major categories: 1) Inflammation or infection, 2) benign tumor, 3) physiologic activity, and 4) iatrogenic.	10750966
Inflammation, Secondary malignant neoplasm of lung, Infectious Lung Disorder, Primary malignant neoplasm	Altered Intercellular Communication	Pulmonary infection or inflammation might predispose patients to localized F-18 FDG chest uptake mimicking pulmonary metastases and limiting the specificity of whole-body scans performed in patients with cancer.	10750966
Osteomyelitis, Inflammation	Altered Intercellular Communication	However, positive results can be caused not only by true osteomyelitis but also by inflammation in the bone or surrounding soft tissues as a result of other causes.	10750968
Inflammation	Altered Intercellular Communication	Pathologically, the muscle biopsy manifests various degrees of inflammation and specific vacuolar degeneration of muscle fibers characterized by paired helical filaments (PHFs) composed of phosphorylated tau.	10751338
Inflammation, Granuloma, Crohn Disease	Altered Intercellular Communication	Histological examination of specimens from the terminal ileum showed severe inflammation without granuloma formation, which led to a diagnosis of Crohn's disease.	10752780
Inflammation, Asthma, Atopy	Altered Intercellular Communication	In atopic subjects with asthma, the dose-response slope for AMP was correlated to S-EPO (r= -0.56; P = 0.01) and S-ECP (r= -0.51, P = 0.02), while no correlation between BHR and inflammation markers was found in the two other patient groups.	10753017
Inflammation, Restenosis	Altered Intercellular Communication	Although inflammation has been postulated to be a major contributor to restenosis after coronary stenting, there is a paucity of data on the relationsip between inflammation and subsequent neointimal formation in humans.	10754347
Inflammation, Restenosis	Altered Intercellular Communication	Only in a porcine experimental model of stent restenosis, foreign body granulation tissue as a cause of inflammation in stent restenosis was reported.	10754347
Inflammation, Intimal proliferation, Restenosis	Altered Intercellular Communication	These findings support the notion that stent restenosis results from SMC hyperplasia and suggest that the foreign body granulation tissue against metals of the stents and de novo lesions could play an important role in chronic inflammation leading to intimal hyperplasia and subsequently to stent restenosis in some patients.	10754347
Inflammation, Gland	Altered Intercellular Communication	Histological examination showed a significantly higher degree of activity, inflammation and glandular atrophy in the antrum and corpus in H. pylori-positive patients compared to H. pylori-negative patients.	10755252
Airway structure	Altered Intercellular Communication	These mechanisms exert several immunoregulatory functions that may be relevant in airway inflammation.	10756220
Inflammation, Vaginitis, Aspects of congenital malformations, Vulvovaginitis, Hymen, Imperforate	Altered Intercellular Communication	The genital tract disorders were represented by inflammation (70%) (vaginitis, vulvovaginitis) and malformations (30%) (labia minora fusion, imperforate hymen, etc).	10756894
Inflammation, Mycoses	Altered Intercellular Communication	The specific inflammation (48.5%) was mycotic (41.1%), bacterial (29.3%), the same pathogen being detected both in urine and vaginal discharge, trichomonal (17.6%), and gonococcal (11.6%).	10756894
Inflammation, Icterus, Lung Diseases, Interstitial, Compression, Malignant Neoplasms, Biliary stricture, PAPILLARY STENOSIS	Altered Intercellular Communication	The causes of jaundice were: malignant tumours in 19 (22.9%), chronic diffuse parenchymatous liver disease in 24, stone common bile duct 22, benign biliary strictures and papillary stenosis in 6, extrinsic biliary compression and inflammation in 12.	10756936
Inflammation, Dysplasia, Hyperplasia	Altered Intercellular Communication	Furthermore, 128 biopsies from 16 advanced achalasic patients were prospectively collected and evaluated for grades of inflammation, hyperplasia, dysplasia and also for p53 and PCNA proteins.	10757119
Inflammation	Altered Intercellular Communication	A retrospective survey of fibrinolysis as an indicator of poor outcome after cardiopulmonary bypass and a possible early sign of systemic inflammation syndrome.	10758466
Inflammation	Altered Intercellular Communication	It is possible that fibrinolysis is a marker for onset of systemic inflammation syndrome.	10758466
Inflammation, Hematoma, Pain Distress Question	Altered Intercellular Communication	To decrease the pressure of evolving and long-standing hematomas, thereby reducing inflammation and pain.	10759806
Inflammation, Cluster Headache	Altered Intercellular Communication	Cluster headache is not associated with signs of a systemic inflammation.	10759931
Inflammation, Cluster Headache	Altered Intercellular Communication	To investigate whether there is clinical or biochemical evidence for a transient systemic inflammation during active periods of cluster headache.	10759931
Inflammation, Cluster Headache	Altered Intercellular Communication	These results were taken as evidence that no systemic inflammation is present during the active cluster headache period.	10759931
Inflammation, Cluster Headache	Altered Intercellular Communication	However, whether a local retro-orbital inflammation underlies the pathophysiology of cluster headache remains obscure.	10759931
Wallerian Degeneration, Aneurysm, Inflammation	Altered Intercellular Communication	Aneurysm formation may be related to degeneration of arterial wall caused by inflammation of the vasa vasorum.	10759951
Inflammatory, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Replication error (RER) is found in inflammatory lesions and associated cancer, suggesting that chronic inflammation could be a risk factor for neoplastic development through causing RER.	10760686
Inflammation, Hepatitis	Altered Intercellular Communication	Iron deposition and progression of disease in chronic hepatitis C. Role of interface hepatitis, portal inflammation, and HFE missense mutations.	10761457
Inflammation, Hepatitis	Altered Intercellular Communication	Total, sinusoidal, and portal HDI increased with stage; grade was related to all iron scores because of the contribution of portal inflammation and interface hepatitis.	10761457
Inflammation	Altered Intercellular Communication	s-IBM is morphologically characterized by primary endomysial inflammation and vacuolated myofibers containing tubulofilaments that originate from cytoskeletal proteins.	10762511
Airway structure, Asthma, Neutrophilia (finding)	Altered Intercellular Communication	We conclude that neutrophils are the dominant inflammatory leukocyte characterizing airway inflammation in acute severe asthma that requires mechanical ventilation, and that IL-8 is an important mediator of this neutrophilia.	10764310
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Serum C-reactive protein (CRP) reflects inflammation and predicts cardiovascular disease in middle-aged individuals.	10764673
Inflammation	Altered Intercellular Communication	In contrast, in the H pylori positive group that became H pylori negative as a result of treatment (n=33), active and chronic inflammation in both the corpus and antrum decreased (p	10764703
Inflammation	Altered Intercellular Communication	The decrease in active and chronic inflammation in the corpus differed significantly compared with the persistently H pylori positive group (both p=0.001).	10764703
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The concomitant enhanced expression of NGF and its receptor suggests activation of this pathway in chronic inflammation in CD and UC.	10764711
Inflammation, Neoplasms	Altered Intercellular Communication	On the other hand, the most frequent causes preventing ureteroscopy are, for both male and female patients, some types of tumor: uterine, ovarian, ureteral, bowel, bladder and prostate cancer, and inflammation.	10765066
Infection, Neoplasms, Benign neoplasm of bladder	Altered Intercellular Communication	On the other hand, tumours of the female reproductive system, as well as bladder and prostate tumours and serious inflammations and infections may make the procedure impossible or cause serious problems during its performance, at times requiring combined antegrade and retrograde maneuverings.	10765066
Inflammation, Malignant Neoplasms, prostatitis	Altered Intercellular Communication	Inflammation in prostate biopsies of men without prostatic malignancy or clinical prostatitis: correlation with total serum PSA and PSA density.	10765070
Inflammation, Malignant Neoplasms, prostatitis	Altered Intercellular Communication	Inflammation is a frequent histological finding in prostate biopsies, performed on men without prostatic malignancy or clinical prostatitis.	10765070
Inflammation, Aggressive behavior	Altered Intercellular Communication	The inflammation in the remaining 145 prostate biopsies was scored for extent of inflammation and aggressiveness of inflammation, using the four-point scale designed by Irani and co-workers.	10765070
Inflammation, prostatitis	Altered Intercellular Communication	In this prostatic inflammation scoring system, extent of inflammation is graded from 0 up to 3 according to the degree of invasion of inflammatory cells in prostatic tissue.	10765070
Inflammation, Prostatic Glandular Cell	Altered Intercellular Communication	Aggressiveness of inflammation is graded from 0 up to 3 according to the degree of contact or disruption of prostatic glandular epithelium by inflammatory cells.	10765070
Inflammation, Aggressive behavior	Altered Intercellular Communication	Median PSA levels in grades 0, 1 and 2 of aggressiveness of inflammation were, respectively, 3.9, 5.9 and 8.9.	10765070
Prostate, prostatitis	Altered Intercellular Communication	Inflammation of the prostate is a histological finding in almost every set of prostate biopsies, even when there are no signs of clinical prostatitis.	10765070
Inflammation	Altered Intercellular Communication	Not the extent of inflammation is of importance, but the disruption of epithelial integrity caused by the inflammatory infiltrate.	10765070
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	When confronted with a patient with an elevated PSA level whose prostate biopsies reveal no malignancy but only inflammation, this concept can help in determining the need for quick repeat biopsies.	10765070
Inflammation, Hypertrophy	Altered Intercellular Communication	To analyze the influence of inflammation and benign prostatic enlargement on total and percent free serum prostatic specific antigen (PSA).	10765091
Inflammation, Acute prostatitis, Chronic prostatitis	Altered Intercellular Communication	Benign tissue without inflammation was found in 23.2% of the patients (group 1), while in 68.3%, it was associated with chronic prostatitis (group 2) and with acute prostatitis in 8.4% (group 3).	10765091
Inflammation	Altered Intercellular Communication	Inflammation has an important prevalence in cancer-free prostatic biopsy specimens.	10765091
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	Sarcoidosis is a prevalent disease of unknown cause characterized by granulomatous inflammation that often creates deep and/or superficial mass lesions.	10767231
Granulomatous inflammation	Altered Intercellular Communication	All aspirates showed granulomatous inflammation; in 22 patients, special stains or cultures for microorganisms were negative.	10767231
Inflammation, Facial edema, Neoplasms, Acne Vulgaris, Infection, Traumatic injury, Neuralgia, Immune System Diseases	Altered Intercellular Communication	Although acute facial edema has been associated with numerous disease processes such as infections, neoplasms, immune disorders, inflammation, neuropathic processes, drugs, mechanical obstructions, and trauma, solid facial edema has most often been associated with acne vulgaris.	10767691
Inflammation	Altered Intercellular Communication	Sialectasis and stricturing occurs in the distal ducts, whereas inflammation of the gland and duct epithelium is probably caused by a low salivary flow rate.	10768114
Inflammation	Altered Intercellular Communication	[Chronic inflammation of the petrous bone with fatal outcome].	10768115
Intraocular inflammation, Retinal Vasculitis	Altered Intercellular Communication	Multiple yellowish spots appeared in the deep retina without evidence of intraocular inflammation or retinal vasculitis, diagnosed clinically as PORN.	10768344
Follicle, Inflammation, Premature tooth loss	Altered Intercellular Communication	The primary variables for data analysis were the presence or absence of the following histologic features: premature loss of the inner root sheath; eccentric placement of shaft, with thinning of the outer root sheath; lamellar fibroplasia surrounding the follicle; loss of sebaceous glands; evidence of follicular destruction or scarring; inflammation; and intrafollicular or perifollicular microorganisms.	10768646
Plasma Cells, Inflammation, Epithelial	Altered Intercellular Communication	The most common findings in the 19 histologically abnormal specimens were perifollicular, chronic (lymphocytic and plasmacytic) inflammation, most intense at the level of the isthmus and lower infundibulum; lamellar fibroplasia, most marked at the level of the isthmus; complete disappearance of sebaceous glands, associated with inflamed or destroyed follicles; thinning of the follicular epithelium, most marked at the level of the isthmus; and total epithelial destruction (superficial and deep), with residual "naked" hair fragments.	10768646
Pancreatitis, Pancreatic Fistula	Altered Intercellular Communication	Stenting does appear to increase the rate of pancreatic fistula formation, possibly as a result of pancreatic inflammation related to the stenting procedure.	10769088
Inflammation, Atherosclerosis	Altered Intercellular Communication	Although CRP is considered a marker of inflammation, it induces monocyte tissue factor (TF) and may play a prothrombotic role in atherosclerosis and its complications.	10769278
Decreased circulating cortisol level, Hypothyroidism	Altered Intercellular Communication	Hormonal examination revealed corticosteroid insufficiency and hypothyroidism, possibly caused by the pituitary mass.	10769847
Inflammation, Arthritis	Altered Intercellular Communication	Adrenocorticotropin, glucocorticoid, and androgen secretion in patients with new onset synovitis/rheumatoid arthritis: relations with indices of inflammation.	10770182
Orbital Pseudotumor, Orbital Myositis	Altered Intercellular Communication	Orbital myositis implies orbital inflammation confined to one or more of the extraocular muscles.	10770885
Interstitial inflammation	Altered Intercellular Communication	The histopathological examination of transbronchial lung biopsy showed interstitial inflammation with marked predominance of lymphocyte with intraalveolar exudate.	10771570
Inflammation, Complication Aspects	Altered Intercellular Communication	Clinical comparisons of the pre- and postseptal orbital complications evidence for more severe and prognostically unfavorable course of the inflammation in the posterior part of the orbit.	10771606
Inflammation, Liver Abscess, Pyogenic	Altered Intercellular Communication	In this case, the pyogenic hepatic abscesses were thus considered to have been caused by an inflammation which spread through the portal vein.	10772125
Inflammation, protein-losing gastroenteropathy, Diarrhea, Rheumatoid Arthritis, Abdominal Pain, Hypoproteinemia	Altered Intercellular Communication	A 69-year-old woman with a 6-year history of rheumatoid arthritis treated solely with an orally administered NSAID had slowly progressing persistent mild abdominal pain and diarrhea, accompanied with marked sing of inflammation as well as hypoproteinemia due to protein-losing gastroenteropathy.	10772127
Inflammation, Gallbladder	Altered Intercellular Communication	In accordance with the four-stage classification of inflammation findings for the resected gallbladder, the inflammation findings on the resected gallbladder indicated a higher correlation with the time required for gallbladder dissection (30.2 +/- 16.3 minutes) than with the operation time (77.6 +/- 32.7 minutes).	10773146
Inflammation, Bulla	Altered Intercellular Communication	After 48 and 72 h, the blisters were intraepithelial, due to basal cell regeneration, and were no longer evident at 96 and 120 h. Dermal inflammation was always mild.	10773698
Inflammation, Pulmonary Fibrosis	Altered Intercellular Communication	Our data demonstrated (i) CA19-9 in BALF correlated with other markers of inflammation in pulmonary fibrosis, and (ii) CA19-9 can modify neutrophil functions.	10773785
Communicable Diseases, Inflammation	Altered Intercellular Communication	They are, however, a risk for infection and chronic inflammation.	10773983
Inflammation, Lymphadenopathy, Tuberculosis	Altered Intercellular Communication	Upon performing a laparotomy, severe adhesive inflammation and adenopathies were found and abdominal tuberculosis was diagnosed.	10774489
Granulomatous inflammation, Eosinophilic inflammation	Altered Intercellular Communication	The response was characterized by accumulation of eosinophilic material or eosinophilic pus adjacent to the parasite with surrounding granulomatous inflammation associated with extensive eosinophil infiltration of the surrounding tissue.	10774712
Inflammation	Altered Intercellular Communication	These results indicate that the appendix tissue contains higher number of B1 (and B) cells compared to the peripheral blood and that these cells play a role in the primary immune response to acute infection/inflammation in the appendix.	10776800
Gingivitis	Altered Intercellular Communication	Those having detectable levels had more gingival inflammation than those having none; however, these differences were significant only in children over the age of 12 years (PDI, BS).	10776927
Inflammation, Colonization	Altered Intercellular Communication	In contrast, while 75% of the children had detectable A. actinomycetemcomitans, there were significant differences in gingival inflammation associated with colonization in children from 3 to 7 years of age (PDI) and over 12 years of age (M-PMA).	10776927
Inflammation, Gastrointestinal Diseases, Infection caused by Helicobacter pylori	Altered Intercellular Communication	We measured cell proliferation and apoptosis in the antral epithelial cells of Helicobacter pylori-infected and H. pylori-uninfected persons, and examined these processes in relation to diagnosis and the histologic parameters of inflammation to investigate their role in cellular turnover in diseases of the upper gastrointestinal tract.	10777155
Inflammation	Altered Intercellular Communication	H. pylori infection was associated with increased apoptosis and cell proliferation in the gastric mucosa, which correlated with the degree of acute inflammation and the density of H. pylori, and these latter two factors correlated with each other.	10777155
Stomach Carcinoma, Gland, Malignant neoplasm of stomach	Altered Intercellular Communication	This decreased proliferation in the adjacent mucosa in gastric cancers compared with findings in the other diseases is thought to be closely related to the relatively decreased acute inflammation, which may, partly, contribute to glandular atrophy in the adjacent mucosa of gastric cancer.	10777155
Inflammation, Communicable Diseases, Specimen Type - Fistula, Candida albicans, Citrobacter freundii	Altered Intercellular Communication	After fistula formation, we could successfully treat the inflammation caused by infection of Citrobacter freundii and Candida albicans with intravenous infusion of both antibiotic and antifungal agents.	10777197
Refractory anemias, Pain Distress Question, Immobile, Inflammation	Altered Intercellular Communication	Interference of RF reactivity, especially in RA patients, may alleviate the pain and immobility resulting from chronic inflammation of the joints.	10777254
Pneumonitis	Altered Intercellular Communication	We hypothesized that VEGF levels in lower respiratory tract secretions may vary with age or with lung inflammation in human beings.	10779049
Inflammation, Observation Method - Coagulation, Venous Thrombosis	Altered Intercellular Communication	Plasma concentrations of three inflammatory mediators, interleukin 6 (IL-6), interleukin 8 (IL-8) and monocyte chemotactic protein 1 (MCP-1), that mediate the cross-talk between inflammation and coagulation, were measured in 182 subjects with recurrent venous thrombosis and 350 healthy subjects recruited through a general practice.	10780312
Airway structure, Coughing, Bronchitis	Altered Intercellular Communication	Airway inflammation, airway responsiveness and cough before and after inhaled budesonide in patients with eosinophilic bronchitis.	10780759
Inflammation, Bronchitis	Altered Intercellular Communication	The authors have tested the hypothesis that in eosinophilic bronchitis the inflammation is mainly localized in the upper airway.	10780759
Inflammation, Airway structure, Coughing, Eosinophilic disorder, Bronchitis	Altered Intercellular Communication	It is concluded that upper airway inflammation is not prominent in eosinophilic bronchitis and that inhaled budesonide improves the sputum eosinophilia, cough severity and sensitivity suggesting a causal link between the inflammation and cough.	10780759
Pericarditis, CTCAE, Myocarditis	Altered Intercellular Communication	ST-segment elevation in acute pericarditis is believed to be caused by superficial myocardial inflammation or epicardial injury.	10781355
Inflammation, Atherosclerosis	Altered Intercellular Communication	Low-grade chronic inflammation, characterized by elevated plasma concentrations of C-reactive protein (CRP), is associated with an increased risk of atherosclerotic cardiovascular disease.	10781383
Inflammation, Endothelial dysfunction, Cardiovascular Diseases	Altered Intercellular Communication	These data demonstrate for the first time a relationship between low-grade chronic inflammation and basal endothelial NO synthesis (measured using an invasive method), and support the notion that endothelial dysfunction is a critical intermediate phenotype in the relationship between inflammation and cardiovascular disease.	10781383
Acute inflammation	Altered Intercellular Communication	Florid acute inflammation was present in all the 4 cases.	10782153
Inflammation, Florida	Altered Intercellular Communication	Acute inflammation is variable and when florid is usually associated with identifiable organisms on histologic examination.	10782153
Inflammation, Asthma, Disease	Altered Intercellular Communication	Eosinophilic inflammation is a crucial aspect of allergic diseases such as bronchial asthma.	10782526
Airway structure	Altered Intercellular Communication	The elevated level of eotaxin detected in association with increased eosinophils and ECP in the sputum of asthmatics suggests that eotaxin is involved in the pathogenesis of eosinophilic airway inflammation.	10782526
Choroidal Effusions, Ocular Hypotension, Neoplasms, Carotid-Cavernous Sinus Fistula	Altered Intercellular Communication	After detection, the various causes of choroidal effusions, such as carotid cavernous fistulas, ocular hypotony, tumors, and inflammatory conditions, should be considered.	10782796
Pain Distress Question, Inflammation	Altered Intercellular Communication	Clinical, laboratory, and radiological assessments of function, pain, inflammation, and damage were also performed according to a standard protocol.	10782823
Ileus, CTCAE, Inflammation, Swelling	Altered Intercellular Communication	On admission, severe inflammation was observed by the laboratory findings, and abdominal X-ray and CT scan revealed ileus with marked swelling of the right ovary.	10783583
Necrotizing granulomatous inflammation, Giant Cell Arteritis	Altered Intercellular Communication	Giant cell arteritis is a chronic granulomatous inflammation of unknown aetiology involving large and medium size arteries in the elderly.	10783678
Dermatitis	Altered Intercellular Communication	All patients displayed skin inflammation at the subcutaneous infusion site.	10784621
Adenocarcinoma, Inflammation	Altered Intercellular Communication	Pap smear performed 1 year later was interpreted as recurrent adenocarcinoma but later downgraded to inflammation.	10785491
Inflammation, Bronchopneumonia, Granuloma	Altered Intercellular Communication	Two open-lung biopsies and one pneumonectomy specimen showed necrotizing granulomatous inflammation merging with areas of more conventional necrotizing bronchopneumonia In one patient, a mediastinal lymph node also showed stellate necrotizing granulomas.	10786801
Necrotizing granulomatous inflammation, Burkholderia cepacia Measurement	Altered Intercellular Communication	B. cepacia needs to be considered in the differential diagnosis of necrotizing granulomatous inflammation.	10786801
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	As a marker of systemic inflammation, raised C-reactive protein (CRP) concentrations which are still within the normal range have been associated with an increased incidence of coronary heart disease (CHD) in non-diabetic subjects.	10787451
Arthritis, Polyarticular	Altered Intercellular Communication	Peripheral arthritis occurring during the disease course was more often polyarticular and needed additional treatment more frequently than joint inflammation presenting at diagnosis.	10788536
Acute and chronic inflammation	Altered Intercellular Communication	The observed changes seem to be connected with the influence of the salt chambers' microclimate on the cells osmolarity disturbances in the nasal mucosa provoked by the non infectious chronic inflammation.	10789185
Liver parenchyma, Bile duct structure	Altered Intercellular Communication	Imaging with magnetic resonance cholangiography using a half-Fourier spinecho sequence, we were able to visualize rapidly and non-invasively a severely abnormal gallbladder, evidence of liver parenchymal inflammation, and biliary duct dilatation.	10791189
Granulomatous inflammation	Altered Intercellular Communication	Histology of skin biopsy specimens showed granulomatous inflammation, and mycobacterial colonies isolated from the skin of each patient were identified as M. avium by DNA hybridization analysis.	10792234
Interstitial inflammation	Altered Intercellular Communication	Impaired monocyte CD11b expression in interstitial inflammation in hemodialysis patients.	10792630
Inflammation	Altered Intercellular Communication	It is not known to what extent intravascular phenotypic alterations in adhesion molecule expression induced by hemodialysis influence the recruitment of monocytes and their ability to up-regulate CD11b at the local site of inflammation in the interstitium.	10792630
Inflammation, Bulla	Altered Intercellular Communication	The blisters were then stimulated with autologous serum (active blister, intense inflammation) or buffer (control blister, intermediate inflammation), respectively.	10792630
Granulomatous inflammation	Altered Intercellular Communication	A skin biopsy specimen showed minimally caseating granulomatous inflammation.	10792804
Inflammation	Altered Intercellular Communication	The number of patients who reported upper respiratory tract inflammation as an initial symptom was also significantly greater in G1 than G2 (eight versus two patients; P < 0.01).	10793024
Cholecystitis	Altered Intercellular Communication	This is suggestive of a cytokines activation which, when other inflammatory processes can be excluded, is likely due to gallbladder inflammation and surgery will likely be indicated.	10793766
Lichen Planus, Inflammation	Altered Intercellular Communication	Less well understood is the association with chronic inflammation, such as seen in lichen planus.	10795082
Inflammation, Necrosis, Muscle Cells	Altered Intercellular Communication	Nineteen EMB specimens of group I had no inflammation and no myocyte necrosis, 12 of group II specimens showed interstitial mononuclear cell infiltration (only) but no myocyte necrosis, and all 9 of group III specimens had evidence of cellular infiltration and myocyte damage.	10796002
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	In those HCV cases showing evidence of necroinflammatory activity (grade) and individual features of portal inflammation, periportal inflammation/piecemeal necrosis, lobular inflammation, and fibrosis (stage), higher NF-kappaB staining intensity scores within bile ducts, proliferating ductules, hepatocytes (piecemeal necrosis: P =.016; stage: P =.030), and lymphocytes (stage: P =.044) and increased number of NF-kappaB-positive cells within bile ducts, proliferating ductules (grade, lobular inflammation, piecemeal necrosis, stage: P =.022), hepatocytes, and lymphocytes were observed.	10796896
Diverticulosis of the duodenum, Inflammation, Mesenteric Venous Thrombosis	Altered Intercellular Communication	We report a case of superior mesenteric vein thrombosis resulting from an inflamed duodenal diverticulum with associated inflammation of the uncinate process of the pancreas.	10796962
Inflammation, Phenomenon, Keratoconjunctivitis Sicca	Altered Intercellular Communication	Whether inflammation is a primary phenomenon in KCS or is the consequence of repetitive abrasion of the ocular surface after tear film deficiency remains to be determined.	10798650
Pituitary Apoplexy	Altered Intercellular Communication	No evident signs of pituitary apoplexy (either on emergency CT or hormonal evaluation) were detected.	10800766
Inflammation	Altered Intercellular Communication	Additional distinctive findings found in small bowel biopsies in the refractory group were subcryptal chronic inflammation (10 of 10) and marked mucosal thinning in three patients.	10800986
Inflammation, Gastric metaplasia	Altered Intercellular Communication	Other nonspecific findings included acute inflammation and gastric metaplasia.	10800986
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Cigarette smoking results in an oxidant/antioxidant imbalance in the lungs and inflammation, which are considered to be key factors in the pathogenesis of chronic obstructive pulmonary disease (COPD).	10802223
Hepatic inflammation	Altered Intercellular Communication	All of these patients had coexistent moderate to severe hepatic inflammation.	10803673
Inflammation, Fibrosis Assessment, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	A thoracoscopic lung biopsy showed interstitial fibrosis, chronic inflammation and a small non-caseating granuloma in lung tissues, which could be induced by external agents such as metals.	10803702
Hepatitis B, Hepatitis	Altered Intercellular Communication	Of the 51 patients, 38 with elevated transaminase, positive hepatitis B e antigen and/or HBV DNA, and histologic evidence of liver inflammation were treated.	10804945
Inflammation, Asthma	Altered Intercellular Communication	Cysteinyl leukotrienes (cysLTs) are considered to be important mediators involved in bronchial asthma and the ensuing eosinophilic inflammation.	10804983
Inflammation, Asthma	Altered Intercellular Communication	These results suggest that cysLTs are important mediators involved in eosinophilic inflammation, a major pathophysiologic feature of bronchial asthma in humans.	10804983
Pain Distress Question, KANTR gene, Inflammation	Altered Intercellular Communication	cutting of the internal anal sphincter, thus eliminating spasm of this muscle and breaking the vicious circle of pain, spasm and inflammation.	10805553
Intraocular inflammation	Altered Intercellular Communication	Apart from intraocular inflammation, no other cause of neovascularization was detected.	10806436
Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	The gingival health of each animal was measured by recording the presence or absence of gingival inflammation, plaque, and bleeding upon probing.	10807121
Inflammation	Altered Intercellular Communication	Increasing evidence suggests that mesothelial cells contribute to the control of inflammation in the peritoneal cavity by secreting prostaglandins.	10807404
Gastro-esophageal reflux disease with esophagitis	Altered Intercellular Communication	Both the manometric and the hormonal changes may exacerbate reflux oesophagitis after distal partial gastrectomy.	10807419
Congestive heart failure, Inflammation, Coronary heart disease	Altered Intercellular Communication	The incidence of CHF is high in the elderly and is related mainly to age, gender, clinical and subclinical coronary heart disease, systolic BP and inflammation.	10807470
Myocarditis	Altered Intercellular Communication	Patients with LM may have ongoing myocardial inflammation.	10807528
Sialorrhea, Gastrointestinal inflammation	Altered Intercellular Communication	Antisecretory factor (AF), a 41 kDa cloned and sequenced protein, suppresses intestinal inflammation and hypersecretion in animals.	10807895
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide (NO) is increased in asthma and may also be increased in subclinical airway inflammation.	10808168
Airway structure, Asthma, MS4A2 wt Allele	Altered Intercellular Communication	The relationship between atopy and subclinical airway inflammation in the pathogenesis of asthma remains unclear.	10808168
Airway structure, Asthma, Atopy	Altered Intercellular Communication	This may denote subclinical airway inflammation in this population and suggests that exposure to HDM in atopic individuals might play an important role in the early pathogenesis of asthma.	10808168
Inflammation, Bulla	Altered Intercellular Communication	The clinical diagnosis was emphysematous bullae with inflammation.	10808298
allergic inflammation	Altered Intercellular Communication	Evidence has now accumulated that heparin can significantly affect immune response including allergic inflammation.	10808384
Inflammation, MS gene	Altered Intercellular Communication	Activated, cytokine-producing lymphocytes may regulate central nervous system (CNS) inflammation in multiple sclerosis (MS).	10809917
Airway structure	Altered Intercellular Communication	Nitric oxide in exhaled air may be an early marker of airway inflammation in aluminium potroom workers.	10810115
Inflammation, Stomach Carcinoma, Neoplasms	Altered Intercellular Communication	We investigated the site of HGF production by analyzing the relationships between the HGF expression in tumor tissues, the serum HGF concentrations and inflammation in patients with gastric cancer.	10810432
Inflammation	Altered Intercellular Communication	The monomorphic clinical aspect of destructive mid-face lesions is characterised by inflammation, induration and granulomatous transformation.	10810680
Inflammation	Altered Intercellular Communication	Apoptosis and clearance of neutrophils is essential for successful resolution of inflammation.	10811006
Inflammation	Altered Intercellular Communication	This allows for rapid resolution of inflammation as levels of survival factors fall, and suggests new strategies for inducing resolution of inflammation.	10811006
Inflammation, Liver damage	Altered Intercellular Communication	The monitoring of patients undergoing bone marrow transplantation indicated that the release of iron-rich and iron-poor ferritin occurred during phases of hepatocellular damage and inflammation, respectively.	10811057
Inflammation	Altered Intercellular Communication	Cytokine interleukin-1beta plays a central role in the inflammation process.	10811344
Inflammation	Altered Intercellular Communication	In SF, the proportion of Th1 and Tcl cells was significantly elevated compared to PB, emphasizing the local importance of these cells for inflammation.	10813277
Inflammation	Altered Intercellular Communication	The upregulation of IL-10-producing Th2 and Tc2 cells in SF may reflect an insufficient effort to down-regulate chronic inflammation in the joint.	10813277
Tumor necrosis, Anemia, Sickle Cell, SLC22A5 gene, Inflammation	Altered Intercellular Communication	Tumor necrosis factor-alpha is undetectable in the plasma of SS patients with elevated Hb F. Steady-state sickle cell disease (SCD) patients may have increased plasma levels of acute phase reactants and pro-inflammatory cytokines because of subclinical inflammation.	10814986
Inflammation	Altered Intercellular Communication	Epitope spreading describes the phenomenon where underlying chronic inflammation leads to the sequential recognition of new epitopes on self-proteins over time.	10815859
Inflammation	Altered Intercellular Communication	Forty-three patients had clinically benign perforations biopsied, and no histology other than chronic inflammation was obtained.	10816212
Secondary hypothyroidism	Altered Intercellular Communication	The patient initially showed hormonal profiles of pituitary hypothyroidism and gonadal hypofunction.	10817242
Asthma, Bronchitis	Altered Intercellular Communication	There is need for relevant markers of bronchial inflammation in epidemiologic studies of asthma.	10817397
Asthma, Eosinophilic inflammation	Altered Intercellular Communication	Serum eosinophil cationic protein (ECP) is a marker of eosinophil inflammation and asthma activity.	10817397
Inflammation, Diabetic Angiopathies, Exacerbation of cGVHD	Altered Intercellular Communication	These 31 disease flares diagnosed over 550 days were associated with symptoms of systemic inflammation but did not result in vascular complications.	10817557
vascular inflammations	Altered Intercellular Communication	Standard corticosteroid regimens only partially suppress vascular inflammation.	10817557
Refractory anemias, Inflammation	Altered Intercellular Communication	These findings indicate a crucial role for FLS in the survival of synovial B cells at the site of inflammation in RA through the interaction with VCAM-1 expressed on FLS.	10817566
Inflammation, Superficial ulcer, Synovitis	Altered Intercellular Communication	Synovitis was greater in SE+ patients, suggesting an early genetic influence on joint inflammation, and was predictive for the development of erosions at 1 yr.	10817774
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Hypertrophy of fibers containing galanin (GAL), the inhibitory neurotransmitter of acetylcholine, occur on remaining cholinergic nucleus basalis neurons in late stage Alzheimer's disease (AD).	10818256
Inflammation, Brain Injuries	Altered Intercellular Communication	Inflammation and alterations in BBB may play lesser, but nonetheless significant, roles in determining the A beta level in CSF after brain injury.	10818496
Alzheimers Disease", vascular inflammations	Altered Intercellular Communication	Alterations of Alzheimer's disease in the cholesterol-fed rabbit, including vascular inflammation.	10818523
vascular inflammations	Altered Intercellular Communication	The data suggest that vascular inflammation can lead to breach of the blood-brain barrier, which may produce biochemical derangements in surrounding brain tissue that are conducive to production of beta-amyloid.	10818523
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	We found no relevant correlation between VIB and biochemical indices of inflammation (ESR, CRP) and between VIB and clinical activity of IBD (CDAI, CAI).	10820861
Inflammation	Altered Intercellular Communication	It can be concluded that the extent of inflammatory changes of the bowel wall detected by US is not strictly associated with clinical activity and laboratory parameters of inflammation.	10820861
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	There were no changes in the scores for inflammation, neutrophil activity, gland atrophy or intestinal metaplasia at the end of the eighth week and at one year following H pylori eradication therapy.	10820906
Inflammation, Atrophic	Altered Intercellular Communication	Nor was there an obvious relationship between trefoil factor expression and pathology, but those glands not expressing TFF1 or TFF3 had evidence of chronic inflammation or atrophy.	10821500
Inflammation, Hypertrophy	Altered Intercellular Communication	The I clinical group consisted of 194 patients in whom, on definite indications, micro-surgeries with Kleinsasser's method were performed and the II control group consisting of 165 subjects suffering from chronic simple inflammation of pharyngo-laryngeal mucosa without morphologic hypertrophy.	10822966
Inflammation	Altered Intercellular Communication	[Monitoring of the inflammation in children before and after tonsillectomy].	10822969
Inflammation	Altered Intercellular Communication	It may mean that at least in some cases the chronic inflammation was caused by streptococci non-producing streptolysin O.	10822969
Inflammation, Necrotizing Enterocolitis	Altered Intercellular Communication	Inflammation in the developing human intestine: A possible pathophysiologic contribution to necrotizing enterocolitis.	10823949
Granulomatous inflammation	Altered Intercellular Communication	With this approach, granulomatous inflammation usually resolves in 2 to 4 months.	10826089
Inflammation	Altered Intercellular Communication	In conclusion, the levels of total protein and IL-6 were increased prior to penetrating keratoplasty in eyes with previous inflammation.	10828736
Inflammation, Amyloidosis	Altered Intercellular Communication	Highly permeable biocompatible dialysis membranes may postpone the development of AB-amyloidosis, but the relative contribution of enhanced flux or reduced inflammation by highly biocompatible membranes and sterile dialysis fluid remains unknown.	10831638
Inflammation	Altered Intercellular Communication	The aim is to clarify the possible existence of a chronic inflammation of the appendix by a clinical and histopathologic study.	10832282
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Chronic appendicitis was diagnosed when at least two typical histological factors of chronic inflammation were present.	10832282
Inflammation, Eye Infection	Altered Intercellular Communication	The ocular infections were characterized by rapid onset, extreme inflammation, and--despite in vitro antibiotic sensitivity--a poor or sluggish response to antibiotic therapy.	10832687
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Whole gut lavage fluid samples may provide a useful investigative tool to study mucosal inflammation and luminal neutrophil migration in ileoanal pouches.	10833100
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Histologically, MGC were smooth, irregular or dendritic in shape, and tended to increase in number in the vicinity of cancer or marked inflammation.	10834385
Inflammation	Altered Intercellular Communication	A wide variation between subjects was recorded for both quantities and profiles of expressed cytokines, despite similar macroscopic and histopathological features of inflammation.	10834861
Inflammation	Altered Intercellular Communication	Specimens acquired arthroscopically from areas with maximum signs of macroscopic inflammation showed an increased number of TNFalpha producing cells in pannus tissue compared with that occurring in synovial villi of a given joint.	10834861
Granulomatous inflammation, Glomerulonephritis, Vasculitis, CTCAE, Systemic Vasculitis	Altered Intercellular Communication	The following diagnostic criteria are proposed for microscopic polyangiitis: (1) Biopsy verified necrotising vasculitis in small vessels and/or glomerulonephritis with few or no immune deposits and (2) Involvement of more than one organ system as indicated by biopsy verified vasculitis in small to medium sized vessels or surrogate parameter for glomerulonephritis and (3) Lack of biopsy and surrogate parameter for granulomatous inflammation in the respiratory system.	10834866
Inflammation, Necrosis	Altered Intercellular Communication	Skin biopsy revealed a granulomatous epithelioid cell inflammation in the corium without central necrosis.	10835982
Inflammation, Calcinosis, Cyst	Altered Intercellular Communication	Histopathology revealed inflammation of the cyst in 2 cases and calcification of the cyst wall in 1.	10836240
Airway structure, Wheezing	Altered Intercellular Communication	An increase in prevalence of wheezing illness in the UK has coincided with a reduction in the consumption of natural antioxidants, which may modulate the lung's response to oxidant stress, limiting the expression of airway inflammation and respiratory symptoms.	10836318
Airway structure, Asthma, Atopy	Altered Intercellular Communication	Exhaled CO and nitric oxide, an expired gas also thought to reflect cytokine-induced airway inflammation, were measured in 15 atopic steroid-naive nonsmoking patients with asthma (13 males, aged 30+/-2 yrs) before and for up to 20 h after allergen challenge.	10836322
Airway structure	Altered Intercellular Communication	In conclusion, airway inflammatory cell numbers are not only increased but also activated, suggesting an important role for airways inflammation in the pathophysiology of chronic nonproductive cough.	10836324
Inflammation, Hemorrhagic Fevers, Viral, Syndrome, Hypotension, CTCAE, Injury of kidney, Thrombocytopenia	Altered Intercellular Communication	Systemic inflammation in hemorrhagic fever with renal syndrome correlates with hypotension and thrombocytopenia but not with renal injury.	10837176
Inflammation, Hemorrhagic Fevers, Viral, Epidemic	Altered Intercellular Communication	Systemic inflammation is common in patients with nephropathia epidemica (NE), a European form of hemorrhagic fever.	10837176
Inflammation, Virus Diseases, Pulmonary Valve Insufficiency	Altered Intercellular Communication	Markers of inflammation were studied in a patient with NE with respiratory insufficiency (patient 1), 18 other patients with NE, and 13 patients with a viral infectious disease other than NE.	10837176
Inflammation, Hypotension, CTCAE, Injury of kidney	Altered Intercellular Communication	Severity of inflammation in patients with NE is related to hypotension and platelet consumption but not to renal injury.	10837176
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The increased expression of HLA-DR on conjunctival epithelial cells still present 6 months after surgery indicates the increased ability of epithelial cells to induce immune inflammation with subsequent fibrosis.	10837395
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Correlation of histological inflammation in needle biopsy specimens with serum prostate- specific antigen levels in men with negative biopsy for prostate cancer.	10840104
Inflammation, Prostate carcinoma	Altered Intercellular Communication	In the assessment of needle biopsy results negative for prostate cancer, it might be helpful to evaluate the degree of histological inflammation, especially in terms of the necessity of subsequent repeated biopsies.	10840104
Inflammation, MS gene	Altered Intercellular Communication	The recruitment of leucocytes to sites of inflammation is an important feature of multiple sclerosis (MS) pathology.	10840276
Inflammation, Colorectal Carcinoma, Neoplasms	Altered Intercellular Communication	Inflammation and desmoplasia around colorectal carcinoma are often present, but may actually enhance EUS detection of microscopic tumor spread.	10840300
Inflammation, Brain Damage, Chronic, prostatitis, SMALL PATELLA SYNDROME, Pelvic Pain, Disease, Elastosis perforans serpiginosa	Altered Intercellular Communication	Chronic Prostatitis, or Chronic Pelvic Pain Syndrome [CPPS], is a common disorder characterized by pelvic pain and varying degrees of inflammation in expressed prostatic secretions (EPS).	10840462
Inflammation	Altered Intercellular Communication	These results suggest that interaction between T cells and muscle cells via the CD40-CD40L system contributes to the immunopathogenesis of PM/DM by augmenting inflammation via cytokine production by the muscle cells.	10843719
Colitis	Altered Intercellular Communication	This study was carried out to investigate the impact of IL-2 deficiency on the neuroendocrine system in normal colon, and the neuroendocrine changes during colonic inflammation.	10844519
Inflammation	Altered Intercellular Communication	Polypeptide YY (PYY) cells and tissue levels of PYY, SP and VIP were significantly decreased in the IL-2-/- mice during the course of bowel inflammation compared with the healthy IL-2+/- and IL-2+/+ controls.	10844519
Inflammation, Consortium for Molecular and Cellular Characterization of Screen-Detected Lesions, Necrosis	Altered Intercellular Communication	Definitive diagnosis of MCL was made when a neck mass persisted for several weeks or months and one or more of the following was obtained: (1) positive mycobacterial cultures from biopsy material; (2) Positive mycobacterial staining of biopsy material; (3) Granulomatous inflammation and caseating necrosis on histopathological examination of biopsy material.	10845042
Inflammation	Altered Intercellular Communication	Arteriovenous nicking was associated with markers of inflammation and vascular endothelial dysfunction (von Willebrand factor and factor VIII).	10845884
Hepatitis B Virus-Related Hepatocellular Carcinoma, FAM126A gene, Necrosis with inflammation	Altered Intercellular Communication	In hepatitis B virus-related hepatocellular carcinoma (HCC), at least 20-40 years of continuous necro-inflammation is necessary for the hepato-carcinogenesis to occur.	10847487
Cryptorchidism	Altered Intercellular Communication	Clinical, physical, sperm and hormonal data in 251 adults operated on for cryptorchidism in childhood.	10848704
Cessation of life, Inflammation, Chronic disease	Altered Intercellular Communication	Inflammation at a low level of intensity may be a common phenomenon associated with the majority of causes of death owing to chronic diseases.	10848841
Inflammatory Bowel Diseases, Inflammation, Protein-Losing Enteropathies	Altered Intercellular Communication	If inflammation in ileoanal pouches is similar to IBD, then measurement of protein-losing enteropathy by analysis of WGLF may provide an objective assessment of disease activity in pouches.	10848863
Inflammation	Altered Intercellular Communication	Analysis of WGLF for IgG and albumin may be useful in the assessment of disease activity in pouch inflammation.	10848863
Necrotizing granulomatous inflammation	Altered Intercellular Communication	All showed infective granulomas/granulomatous inflammation on histology.	10849123
Inflammation, Primary malignant neoplasm, Gastrointestinal mucositis, Necrosis	Altered Intercellular Communication	Mucositis, the inflammation and necrosis of mucosal membranes, is a serious and debilitating consequence of many cancer therapies.	10850381
Granulomatous inflammation	Altered Intercellular Communication	Molecular detection of Mycobacterium tuberculosis in tissues showing granulomatous inflammation without demonstrable acid-fast bacilli.	10850541
Granulomatous inflammation	Altered Intercellular Communication	It is not uncommon to observe granulomatous inflammation but without demonstrable acid-fast bacilli (AFB) on Ziehl-Neelsen (ZN) staining in tissues sent for histologic examination, and the definitive diagnosis of TB cannot be made because no concurrent tissue is sent for TB culture.	10850541
Granulomatous inflammation	Altered Intercellular Communication	One hundred fifteen patients (131 paraffin blocks of biopsy specimens) with granulomatous inflammation but ZN-negative for AFB were studied.	10850541
Inflammation, Hemorrhage, Nerve Degeneration, Trauma, Nervous System, Loss, Smooth muscle (tissue), Chemical injury, Abnormal degeneration	Altered Intercellular Communication	In both disease conditions, we found evidence of ischemic injury (multifocal fiber degeneration and loss, perineurial degeneration and scarring, characteristic fiber alterations, neovascularization, and injury neuroma) that we attribute to microvasculitis (mural and perivascular mononuclear inflammation of microvessels, inflammatory separation, fragmentation and destruction of mural smooth muscle, and previous microscopic bleeding [hemosiderin]).	10850865
Inflammation, Fever, CTCAE, Chills, CTCAE, Bothered by Vomiting, Nausea	Altered Intercellular Communication	Side effects included fever, chills, nausea, vomiting, and transient inflammation and induration at the injection sites.	10851506
Eosinophilic disorder, Asthma, Airway structure	Altered Intercellular Communication	Eosinophilia is a feature of airway inflammation associated with asthma.	10852761
Inflammation, Dental caries	Altered Intercellular Communication	Improper margins can cause overhangs and overcontouring that may ultimately result in caries, periodontal inflammation and breakdown, and compromised aesthetics.	10853599
Inflammation, Asthma	Altered Intercellular Communication	The level of exhaled nitric oxide and the relationships between lung function, bronchial reactivity and markers of inflammation are different between steroid-treated and untreated asthmatic children.	10853846
Bronchitis, Chronic, Inflammation	Altered Intercellular Communication	Airways inflammation in chronic bronchitis is thought predominantly to be a direct consequence of neutrophil recruitment and release of elastase in response to factors such as cigarette smoke.	10853853
Inflammation, Emphysematous bronchitis	Altered Intercellular Communication	Airways inflammation was compared between patients with chronic obstructive bronchitis with (n=39) and without (n=42) severe alpha1AT deficiency.	10853853
Inflammation	Altered Intercellular Communication	Patients with alpha1-antitrypsin deficiency had greater inflammation suggesting that alpha1-antitrypsin plays an important role in protecting the larger airways from the inflammatory effects of elastase activity and may explain their more rapid progression of disease.	10853853
Inflammation	Altered Intercellular Communication	At time of diagnosis, "signs of florid inflammation" were seen in 60% of the roentgenograms, in 93% of the CTs and in all of the MRls.	10853888
Inflammation, Ulcer	Altered Intercellular Communication	Repeated pressure with each step can result in inflammation at specific points, followed by ulcer formation.	10854887
Inflammation, Dental Plaque	Altered Intercellular Communication	Inflammation and matrix degrading proteases (MMPs) may play a role in both plaque vulnerability and in expansive arterial remodeling.	10856516
Inflammation, destruction joint	Altered Intercellular Communication	These data support a role of these cells in the local autoimmune response that leads to chronic inflammation and joint destruction.	10857782
Acute inflammation	Altered Intercellular Communication	To compare postoperative inflammation occurring with heparin-surface-modified (HSM) versus non-HSM polymethyl methacrylate intraocular lenses (IOLs) after phacoemulsification.	10857818
Acute inflammation	Altered Intercellular Communication	Primary measures of postoperative inflammation defined as the presence of giant cells on the lens surface via specular micrography and cellular deposits via slit-lamp examination.	10857818
Late Onset Disorders, Inflammation	Altered Intercellular Communication	Five eyes of five patients with late-onset or recurrent inflammation after exposure to bacteria-contaminated viscoelastic material were studied.	10857819
Intraocular inflammation	Altered Intercellular Communication	Elevated intraocular pressure during intraocular inflammation occurred in 90% of patients (28 of 31).	10857838
Inflammation, Infection	Altered Intercellular Communication	IP-10 and Mig may contribute to host defense in Th1-mediated host defense during infections by attracting CXCR3(+) Th1 cells to the site of inflammation.	10858199
ARCN1 gene, Airway structure	Altered Intercellular Communication	In stable patients with COPD, inhaled steroid treatment may induce changes on some cellular and molecular parameters of airway inflammation.	10858395
Pneumonitis	Altered Intercellular Communication	The central role of apoptosis in the regulation of lung inflammation is increasingly recognized.	10858402
Pneumonitis	Altered Intercellular Communication	Pulmonary neutrophils from patients with CAP show a decreased rate of apoptosis and increased activation status in the alveolar compartment, which may be important for effective control of pulmonary inflammation.	10858402
Inflammation, Edema	Altered Intercellular Communication	Histologic examination in that case revealed a subepithelial nodular aggregate of atypical large dyscohesive cells with accompanying edema and inflammation.	10863233
Nephritis, Interstitial, Inflammation	Altered Intercellular Communication	The interstitial nephritis and nonspecific inflammation of intestine were found by the tissue biopsy.	10863333
Inflammation, Hemorrhage	Altered Intercellular Communication	Bleeding on probing (BOP) is the most significant clinical parameter for the assessment of periodontal inflammation.	10863964
Inflammation, Communicable Diseases, beta Thalassemia, Anemia, Malignant Neoplasms	Altered Intercellular Communication	Underlying causes of RT were malignancy (25/70 or 35.7%), infection (16/70 or 22.9%), postsplenectomized beta-thalassemia/Hb E (11/70 or 15.7%), inflammation (12/70 or 17.1%), iron deficiency anemia (6/70 or 8.6%).	10865414
Hormone abnormality, Chronic disease, Lupus Erythematosus, Systemic	Altered Intercellular Communication	However, whether these hormonal abnormalities are intrinsic to SLE or the consequence of any non-specific chronic disorders cannot be distinguished from the current data.	10866095
Inflammation, Hemoptysis	Altered Intercellular Communication	The hemoptysis was thought to have been caused by changes in the cystic formation in combination with inflammation which extended to the lung.	10867605
Presenile dementia, Inflammation, "Alzheimers Disease", Lewy Bodies	Altered Intercellular Communication	Cortical inflammation in Alzheimer disease but not dementia with Lewy bodies.	10867778
Presenile dementia, Inflammation, Lewy Bodies, Dementia	Altered Intercellular Communication	There have been no previous studies on the role of inflammation in the brain for the second most common dementing disorder, dementia with Lewy bodies.	10867778
Inflammation, Lewy Bodies, Presenile dementia, "Alzheimers Disease", dendritic lamellar body, Data types - Address	Altered Intercellular Communication	To investigate the degree of cortical inflammation in dementia with Lewy bodies (DLB) compared with Alzheimer disease (AD) and control brains.	10867778
Inflammation, dendritic lamellar body, Data types - Address	Altered Intercellular Communication	Compared with AD, DLB demonstrated significantly less inflammation in the form of HLA-DR-reactive microglia in all cortical regions (P<.001, posthoc).	10867778
Inflammation, dendritic lamellar body	Altered Intercellular Communication	The level of inflammation in DLB was comparable to that seen in controls (P=.54, post hoc).	10867778
Inflammation, Data types - Address	Altered Intercellular Communication	Inflammation appears related to the tau neuritic plaques of AD.	10867778
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Variables analyzed included neuropsychological test scores and amount of tissue inflammation and Alzheimer-type pathological changes.	10867780
Inflammation, Communicable Diseases, Vulvovaginitis, Glossitis, Candidiasis	Altered Intercellular Communication	She presented with the following symptoms: oral candidiasis and glossitis, angulus infectious, vulvovaginitis, lichen planus-like onychodystrophy of the finger-nails and chronic nail bed inflammation of the nails of the big toes.	10868017
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	A growing amount of data supports the role of inflammation in the pathophysiology of atherosclerotic diseases but the cellular source of cytokines has not been clearly identified.	10868926
Renal Insufficiency, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Our data, however, argue against the hypotheses of sVCAM-1 levels simply being a marker of endothelial dysfunction, of low-grade inflammation, or of an impaired renal function.	10868972
Parkinsonian Disorders	Altered Intercellular Communication	These findings indicate that dysregulation of two neurotransmitter systems within the basal ganglia may underlie common parkinsonian symptoms in these disorders.	10869053
Inflammation	Altered Intercellular Communication	Unstable angina (UA) is associated with systemic inflammation and with expansion of interferon-gamma-producing T lymphocytes.	10869258
Inflammation	Altered Intercellular Communication	NFkappaB activation may induce a myocardial proinflammatory state, possibly making the unstable myocardium more susceptible to the inflammation induced by open heart surgery.	10869529
Inflammation	Altered Intercellular Communication	Pathologic findings included periurethral hemorrhagic necrosis, with focal or extensive urothelial denudation and mild inflammation.	10869628
Inflammation, Data types - Address	Altered Intercellular Communication	Further, as inflammation is reported to play a prominent role is AD pathogenesis, IL-6, a known mediator of inflammation, is another candidate gene proposed to be associated with the risk of AD.	10869806
Airway structure, Burn Specimen Source Codes, Inflammation	Altered Intercellular Communication	These results suggest that NO reflects the intensity of inflammation in the early burn stage, but that excessive NO formation is unlikely to be induced by stress, such as that caused by airway burn.	10869821
Asthma, Hyperreactivity	Altered Intercellular Communication	Inflammation of the airway wall is a defining feature in asthma and is likely the cause of the hyperreactivity and variable airflow limitation found in asthma.	10871433
Airway structure, Asthma	Altered Intercellular Communication	Immune response biased toward production of Th2 cytokines has been proposed as a mechanism in the pathogenesis of airway inflammation in asthma.	10871433
Airway structure, Asthma	Altered Intercellular Communication	The Th2 cytokine interleukin-9 (IL-9) is one candidate gene for asthma on the basis of position cloning and animal models of airway inflammation.	10871433
Airway structure, Inflammation	Altered Intercellular Communication	To determine whether IL-9 is involved in the chronic inflammation of the asthmatic airway, we investigated the expression of IL-9 and the IL-9 specific receptor chain in asthmatic airways compared with healthy airways.	10871433
Airway structure, Asthma	Altered Intercellular Communication	Our results support that IL-9 may play a role in the mechanism leading to chronic airway inflammation and asthma.	10871433
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Edema of the lamina propria was present in 3 cases, whereas lamina propria fibrosis and chronic inflammation were present in all cases.	10872660
Inflammation, Ankylosis	Altered Intercellular Communication	No evidence of root resorption, ankylosis, or untoward inflammation was seen.	10872956
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Here, we demonstrate that a highly stressful event in the absence of systemic inflammation, as observed in patients with acute myocardial infarction, leads to the development of an active HCMV infection in latently infected patients.	10873779
Inflammation, Arthropathy	Altered Intercellular Communication	Thus increased levels of HC gp-39 do not only reflect joint disease but also reflect inflammation or tissue degradation in various conditions.	10873965
Rheumatoid Arthritis	Altered Intercellular Communication	Raised human cartilage glycoprotein-39 plasma levels in patients with rheumatoid arthritis and other inflammatory conditions.	10873965
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	To evaluate plasma human cartilage glycoprotein (HC gp-39) as a possible marker for the presence and/or activity of rheumatoid arthritis (RA) and other inflammatory conditions.	10873965
Inflammatory Bowel Diseases, Arthropathy, Refractory anemias, Lupus Erythematosus, Systemic, Degenerative polyarthritis	Altered Intercellular Communication	The plasma level of HC gp-39 is increased in inflammatory conditions with and without joint disease (SLE, IBD, OA, and RA).	10873965
Inflammation, Uveitis	Altered Intercellular Communication	Presence of sequelae of uveitis without current active inflammation was defined as inactive uveitis.	10873978
Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is a complex histopathologic process that is analogous to chronic inflammatory conditions.	10875038
Corneal decompensation, Inflammation	Altered Intercellular Communication	We suspect that the corneal decompensation was a manifestation of sterile inflammation.	10875086
Inflammation, "Bowens Disease	Altered Intercellular Communication	One again showed the features of a plasmacellular inflammation, while the other finally revealed the histopathologic features of erythroplasia of Queyrat (carcinoma in situ or Bowen's disease of the glans penis).	10879310
Neoplastic, Carcinoma, Balanitis circumscripta plasmacellularis, Inflammation	Altered Intercellular Communication	We assume that either the former biopsy specimens were taken from a plasma cell-rich reactive infiltrate around the neoplastic lesion, or that carcinoma in situ may have arisen due to the chronic inflammation of Zoon's balanitis plasmacellularis.	10879310
Inflammation, Destruction of tissue, Seizures, Rasmussen Syndrome, Neuropsychiatry	Altered Intercellular Communication	Rasmussen's syndrome is characterized by intractable seizures and progressive neuropsychiatric deterioration secondary to unilateral cortical inflammation and tissue destruction.	10879711
COLLAGENOSIS, FAMILIAL REACTIVE PERFORATING, Inflammation	Altered Intercellular Communication	RPC afflicts patients with recurrent and often progressive episodes of inflammation with the potential for destruction of the affected structures.	10879785
Edema, Orbital Pseudotumor, Paralysed	Altered Intercellular Communication	Lid edema, orbital inflammation, muscle palsies, and corneal melting may also occur.	10879785
Inflammation, Chronic infectious disease	Altered Intercellular Communication	Interestingly, sHSP60 was also correlated with anti-lipopolysaccharide, anti-Chlamydia and anti-HSP60 antibodies, various markers of inflammation, and the presence of chronic infections.	10880409
Inflammation, Atherosclerosis	Altered Intercellular Communication	Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS).	10880413
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation has been suggested as a risk factor for the development of atherosclerosis.	10880413
Inflammation, Insulin insensitivity	Altered Intercellular Communication	We hypothesized that insulin insensitivity, as directly measured, may be associated with inflammation in nondiabetic subjects.	10880413
Inflammation	Altered Intercellular Communication	We suggest that chronic subclinical inflammation is part of IRS.	10880413
Inflammation, Fibromyalgia, Musculoskeletal Pain	Altered Intercellular Communication	"Muscular rheumatism" has earlier been looked upon as a (rheumatic) inflammation of muscle cells or of muscular connective tissue.	10881523
Inflammation, Synovitis	Altered Intercellular Communication	Therefore, the pattern of cellular infiltration in human synovitis and the corresponding clinical signs of inflammation basically reflect the localisation and expression intensity of chemokines, which may be an important target for future disease modulation.	10881738
Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	The clinical parameters were pocket depth, gingival inflammation, plaque accumulation, bleeding on probing and pus discharge.	10883869
Disorder of endocrine ovary	Altered Intercellular Communication	This report explores the possibility that the biological mechanism of ovarian dysfunction and decline may affect the menstrual and menopausal changes that result from hormonal imbalances.	10883944
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	RPF is characterized by replacement of the normal tissue of the retroperitoneum with fibrosis and/or chronic inflammation.	10884739
Airway structure, Chronic Obstructive Airway Disease, Fibrosis Assessment, Bronchiectasis	Altered Intercellular Communication	In addition, evidence is presented that urinary desmosine excretion is increased in conditions characterized by airway inflammation, such as exacerbations of chronic obstructive pulmonary disease, bronchiectasis and cystic fibrosis.	10885422
Inflammation, Bulla	Altered Intercellular Communication	Therapies which aim to inhibit production of eotaxin and IL-5 may improve the inflammation and blister formation in BP.	10886144
Inflammation	Altered Intercellular Communication	A number of adhesion molecules participate in the recruitment of inflammatory cells to the site of inflammation, and selectins together with their ligands are important in the early transient adhesion phase.	10886252
Inflammation, Hepatobiliary Disorder, Hepatitis B, Fibrosis Assessment	Altered Intercellular Communication	In 124 hepatitis B e antigen-negative (HBeAg-) patients, the majority with mild liver disease, log HBV DNA levels showed a Gaussian distribution around a geometric mean of 33 000 genome copies ml-1, and increasing HBV DNA level was associated with significantly higher inflammation (HAIinfl) and fibrosis (HAIfibr) scores and higher ALTi (ALT / the upper reference value).	10886534
Disease, Ulcer	Altered Intercellular Communication	A diagnostic examination for short stature in a boy with chronic ulcers of the feet due to prolidase deficiency, a rare disorder associated with intractable ulcers of the skin, led to the diagnosis of growth hormone (GH) deficiency.	10886759
Inflammation, Asthma	Altered Intercellular Communication	Eosinophilic inflammation of the airways is a key characteristic of asthma.	10887309
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Histopathologic examination of the lymph node revealed granulomatous inflammation with caseation necrosis, but did not reveal acid-fast bacilli.	10889098
Uveitis	Altered Intercellular Communication	In case of a repeated AMT, the use of AM from different donors may help to minimize the risk of an immediate postoperative intraocular inflammation.	10889109
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Surrogate markers of intestinal inflammation are predictive of relapse in patients with inflammatory bowel disease.	10889150
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	We assessed whether measurement of intestinal permeability and inflammation could predict relapse of inflammatory bowel disease (IBD).	10889150
ACAA1 gene, Inflammation, Villous, Premature Obstetric Labor	Altered Intercellular Communication	Placental correlates of acute inflammation and villous edema were associated with preterm labor (PTL), prelabor premature rupture of membranes (PROM), lower gestational age, and higher birth weight Z score.	10890926
ACAA1 gene, Rupture, Inflammation	Altered Intercellular Communication	In PTL pregnancies delivered within 1 h of membrane rupture, 61% of placentas already had membrane inflammation.	10890926
ACAA1 gene, Inflammation, Communicable Diseases	Altered Intercellular Communication	The presence of multiple histologic findings consistent with inflammation in placentas of PTL pregnancies with duration of ROM lasting <1 h suggests that some cases of PTL are precipitated by a more long-standing infection than that previously suspected.	10890926
Inflammation, Encephalitis	Altered Intercellular Communication	The concept of brain softening according to Rostan was harshly fought by the followers of the Broussais's physiological medicine (from Lallemand, 1830 to Calmeil, 1859) who claimed that all brain softenings were due to the inflammation process and thus should be described as encephalitis.	10891794
Inflammation, Perivascular inflammation, Vasculitis, CTCAE, Necrosis	Altered Intercellular Communication	Six patients showed "perivasculitis" with mononuclear cell infiltrates around small epineurial vessels without vasculitis (fibrinoid necrosis or transmural inflammation).	10891910
Presenile dementia, Inflammation, dendritic lamellar body, Lewy Bodies	Altered Intercellular Communication	To investigate the role of cerebral inflammation in dementia with Lewy bodies (DLB), activated microglial cells were quantified in postmortem brain tissue.	10891923
Inflammation, dendritic lamellar body, Data types - Address	Altered Intercellular Communication	This study demonstrates the presence of significant inflammation in DLB, even in the absence of AD pathology.	10891923
Inflammation, Hemorrhage	Altered Intercellular Communication	Histological examination suggested that the hemorrhage originated from the many thin blood vessels in the cyst wall stroma associated with inflammation.	10892270
Inflammation	Altered Intercellular Communication	The remaining three patients had normal olfactory function despite moderate chronic inflammation.	10892672
Keratopathy, Inflammation	Altered Intercellular Communication	Patients were categorized into four groups: group 1 (n = 4), high risk patients with stromal vascularization before keratoplasty; group 2 (n = 2), patients with progressive lipid keratopathy; group 3 (n = 4), post keratoplasty patients with active rejection episodes associated with vessels; and group 4 (n = 4), patients with disciform vascularized scars with recurrent inflammation.	10892856
Inflammation, polyps, Stenosis	Altered Intercellular Communication	Endoscopic lithotripsy seems to be effective first line therapy for chronically impacted stones which are frequently associated with chronic inflammation, polyps and strictures, and avoids the futile repetition of ESWL and problems related to the prolonged passage of stone fragments.	10893577
Inflammation, Thrombosis, Coronary Artery Disease	Altered Intercellular Communication	Several studies have shown that thrombosis and inflammation play an important role in the pathogenesis of coronary artery disease (CAD).	10894904
Inflammation, Spondylitis	Altered Intercellular Communication	Is 99mTc human immunoglobulin G scintigraphy (HIG-scan) useful for the detection of spinal inflammation in ankylosing spondylitis?	10895377
Inflammation, Spondylitis	Altered Intercellular Communication	To determine the effectiveness of technetium-99m labelled polyclonal human immunoglobulin G (HIG-scan) scintigraphy to detect spinal inflammation in patients with ankylosing spondylitis.	10895377
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	These changes included mild fibrosis and chronic inflammation of lamina propria with mild architectural distortion.	10895824
Inflammation, Keratosis, Atrophic	Altered Intercellular Communication	Subepithelial inflammation was present and was most intense in areas with severe atrophy and/or keratosis.	10900099
Inflammation, Atrophic	Altered Intercellular Communication	The degree of chronic atrophy and inflammation was not clinically significant.	10900099
Inflammation	Altered Intercellular Communication	Chemokines have been shown to play an important role in the activation and directional migration of cells to sites of CNS inflammation.	10900353
Rectum and sigmoid colon, Tubo-ovarian abscess, Endometritis	Altered Intercellular Communication	Pathology revealed acute and chronic endometritis, left tuboovarian abscess and extensive, acute inflammation of the rectosigmoid colon without evidence of diverticuli.	10900590
Inflammation, Tuberculosis, Pulmonary	Altered Intercellular Communication	The relationship was examined between the bacteriological (growth time, the count of M. tuberculosis colonies) and biochemical (serum haptoglobin and ceruloplasmin levels) indices that characterize the magnitude of inflammation in 653 patients with different forms of pulmonary tuberculosis.	10900986
Inflammation	Altered Intercellular Communication	Little is known about the long-standing inflammation leading to calcification within heart valves.	10901517
Inflammation, Mitral Valve Stenosis, Leaflet of mitral valve	Altered Intercellular Communication	The purpose of the study was to investigate whether osteopontin exists in calcific mitral valve leaflets in human beings, and to determine a link between chronic inflammation leading to mitral stenosis and the osteopontin status of mitral valvular tissue.	10901517
physiopathological	Altered Intercellular Communication	Abnormalities of parasympathetic neurotransmission may contribute to the glandular dysfunction.	10902771
Inflammatory Hepatocellular Adenoma	Altered Intercellular Communication	Co-infection of HGV does not compound hepatocellular inflammation.	10902972
Allergic asthma, Airway structure	Altered Intercellular Communication	Recently, the number of DCs in the large airways was demonstrated to increase in patients with atopic asthma, leading to the concept that DCs play an important role in airway inflammation.	10903234
Inflammation, Coronary heart disease	Altered Intercellular Communication	Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses.	10903648
Communicable Diseases, Inflammation, Coronary heart disease	Altered Intercellular Communication	To assess associations between baseline values of four different circulating markers of inflammation and future risk of coronary heart disease, potential triggers of systemic inflammation (such as persistent infection), and other markers of inflammation.	10903648
Inflammation	Altered Intercellular Communication	Keratinocytes are increasingly recognized as key regulators of skin inflammation and remodeling, as they are capable of producing growth factors and cytokines that are important mediators in the wound healing process.	10903802
Inflammation, Dilated Cardiomyopathy Pathway, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Thirty-nine patients with myocarditis and dilated cardiomyopathy with and without inflammation were examined by a direct immunofluorescence assay using the endomyocardial biopsy as antigen.	10904844
Inflammation, Dilated Cardiomyopathy Pathway, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Fourteen of patients were considered to have myocarditis (group 1), 9 dilated cardiomyopathy with inflammation (group 2), 10 dilated cardiomyopathy (group 3), 6 to have no myocarditis or dilated cardiomyopathy (group 4).	10904844
Inflammation, Atherosclerosis	Altered Intercellular Communication	Whether copper directly affects atherogenesis or is a marker of inflammation associated with atherosclerosis remains to be established.	10905530
Degenerative polyarthritis, Inflammation, Pain Distress Question	Altered Intercellular Communication	These findings suggest that free nerve endings containing substance P may modulate inflammation and the pain pathway in osteoarthritis.	10906873
Ectropion of cervix, Chlamydia	Altered Intercellular Communication	Hormonal contraception and cervical ectopy were previously suggested risk factors for chlamydia.	10907905
Poliomyelitis	Altered Intercellular Communication	Autopsy in one patient showed severe cervicothoracic inflammation with changes almost exclusively in anterior horn cells and roots, as typically seen in poliomyelitis.	10908911
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Perioperative complications were seen in 6 patients: Bleeding (1), subcutaneous emphysema without (3) or with (1) inflammation, inflammation without emphysema (1).	10909028
Inflammation, Communicable Diseases, Infant, Premature, Traumatic injury, Kidney Diseases, Thrombocytosis, Hematological Disease	Altered Intercellular Communication	The causes of thrombocytosis in children are considered to be mostly due to infection, trauma, surgery, blood disease, prematurity, renal disease and chronic inflammation.	10910539
Inflammation, Splenectomy, Tissue damage, Infection, Infant, Premature, Malignant Neoplasms, Kidney Diseases, Thrombocytosis, Hematological Disease	Altered Intercellular Communication	The causes of thrombocytosis are infections (49.5%), Kawasaki disease (6.4%), postsplenectomy (7.8%), blood diseases (3.7%), malignancies (3.2%), renal disorders (3.2%), prematurity (3.2%), tissue damage (4.5%), chronic inflammation (1.8%), recovery from marrow suppression (1.3%), immunologic disturbances (2.2%), essential thrombocythemia (0.5%), and miscellaneous factors (3.7%).	10910539
Icterus, Diarrhea	Altered Intercellular Communication	She displayed neither clinical picture of jaundice, nor excessive hormonal manifestations such as diarrhea or flushing.	10910612
Endometrial Stromal Sarcoma	Altered Intercellular Communication	The similarity between low-grade stromal sarcoma and stromal nodule suggests that stromal nodules might respond to hormonal management.	10912400
Acute and chronic inflammation, Ulcerative Colitis, Allergy - Charge Type Reason	Altered Intercellular Communication	In this report we have investigated the presence of allergy and its possible relation with chronic colonic inflammation in patients with UC.	10912663
Inflammation, Myositis, CTCAE 5.0	Altered Intercellular Communication	Except for the absence of significant inflammation the histopathology is similar to that found in sporadic inclusion body myositis (s-IBM).	10912916
Infarction, Ischemia	Altered Intercellular Communication	Its presence in healing but not early acute stages of infarct suggests that EMH results from inflammation- or repair-associated trophic factors, not from ischemia itself.	10912938
Inflammation, Corneal Opacity	Altered Intercellular Communication	Neither corneal opacity nor aqueous inflammation was present.	10913652
Inflammation	Altered Intercellular Communication	Mucosal biopsies of diverted colon revealed chronic inflammation in all patients, severe inflammation in 13 of 19 subjects at < or = 20 cm from the anus, and in 3 of 10 at > 20 cm (p = 0.06).	10914356
Tissue damage, Inflammation, Play	Altered Intercellular Communication	Delays in this apoptotic response are associated with persistent inflammation and subsequent tissue damage.	10914485
Sample Size Calculation, Upper Respiratory Infections	Altered Intercellular Communication	The increased concentration of exhaled NO in patients with SSc may reflect respiratory tract inflammation.	10914853
Inflammation, Venous Insufficiency	Altered Intercellular Communication	Examination disclosed an increased volume of the tarsal dorsum, with rubbery consistency, with no evidence of venous or lymphatic insufficiency, godette, or inflammation in laboratory tests, giving the foot the appearance of a tamale.	10914870
Inflammation	Altered Intercellular Communication	Tamale foot in juvenile AS may develop as a consequence of acid MPS deposit with no evidence of synovial inflammation.	10914870
Gingivitis, Dental Plaque	Altered Intercellular Communication	Factors tested for correlation were serum phenytoin and folate levels, age, bacterial plaque, gingival inflammation, toothbrushing, smoking and alcohol consumption.	10914892
Inflammation	Altered Intercellular Communication	The findings suggest that the oral gingiva in HIV+ patients may be affected by inflammation.	10914893
Inflammation	Altered Intercellular Communication	The reduction in inflammation resulting from effective periodontal treatment is associated with a reduction in the levels of tachykinins in gingival crevicular fluid.	10914895
Inflammation	Altered Intercellular Communication	Increasing levels of these molecules were closely correlated with the mounting severity of adverse reactions, which raises the possibility that they play an important role in systemic inflammation that arises after DEC treatment of filarial patients.	10915090
Inflammation, Waldenstrom Macroglobulinemia, Hepatitis, Insemination, Artificial, Homologous	Altered Intercellular Communication	We conclude that (1) recurrent AIH is not uncommon and was seen in 42% of patients with lymphoplasmacytic lobular, portal, and interface hepatitis; (2) acidophil bodies with lymphoplasmacytic cells are seen in early recurrent AIH; (3) recurrent AIH appears at variable time periods post-LT, and the progression is slow; and (4) high-grade inflammation in native liver at LT is a strong predictor of recurrent AIH.	10915722
Portal inflammation, Fatty degeneration	Altered Intercellular Communication	In the nontumoral liver, periportal and lobular necrosis, mild portal inflammation, steatosis, and iron overload were present in 15%, 57%, 52%, and 54% of cases, respectively.	10915724
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	End-stage renal disease (ESRD) patients are known to suffer from chronic inflammation as the result of an ongoing subacute cytokine induction, which may contribute considerably to dialysis-related, long-term morbidity and mortality.	10916061
Inflammation, cell injury, Atherosclerosis	Altered Intercellular Communication	ROS may cause cell damage and are involved in the pathophysiology of several diseases, including atherosclerosis and chronic inflammation.	10916112
Neurogenic Inflammation, Prurigo nodularis	Altered Intercellular Communication	CGRP-immunoreactive nerves in prurigo nodularis--an exploration of neurogenic inflammation.	10917163
Neurogenic Inflammation	Altered Intercellular Communication	The results indicate that certain neurons increasingly express CGRP, which may dynamically result in a neurogenic inflammation in the lesional skin, through vasodilatation, and recruitment and regulation of inflammatory cells, e.g.	10917163
Bronchitis, Chronic, Inflammatory, Airway structure	Altered Intercellular Communication	During exacerbations of chronic bronchitis, airway inflammation shows some features of asthmatic inflammatory processes, with recruitment of eosinophils and recovery of significant amounts of ECP in bronchial lavage fluid (BAL).	10917466
Inflammation, Mesothelioma	Altered Intercellular Communication	Mesothelioma arises in a context of asbestos exposure and chronic inflammation, which would be expected to enhance the expression of these inducible enzymes.	10919635
Inflammation, Neuropathy	Altered Intercellular Communication	One is mild gouty neuropathy, the other low-grade inflammation.	10920575
Inflammation, Fibrosis Assessment, Hepatitis, Chronic, FAM126A gene	Altered Intercellular Communication	Univariable analysis indicated that age at entry, fibrosis stage, inflammation activity and the status of IFN treatment (treated vs untreated) were predictive risk factors for developing HCC in patients with chronic hepatitis C. Multivariable analysis of these risk factors indicated that age at entry (> 50 vs < 50; Risk Ratio = 3.2, P< 0.005) and fibrosis stage (F3 vs F0; Risk Ratio= 5.6, P< 0.005) are independent risk factors for HCC.	10921392
ARCN1 gene, Asthma, Pneumonitis	Altered Intercellular Communication	These results suggest that there may be increased oxidative stress in patients with asthma and COPD, and indicate that oxidative stress could possibly attribute to the pathophysiology of asthma and COPD in leading to airflow obstruction and that theophylline could potentially inhibit oxidative stress in the process of bronchopulmonary inflammation in asthmatics.	10921764
Inflammation, Coronary Lesions Treated, Acute myocardial infarction, Myocardial, Atherosclerotic lesion	Altered Intercellular Communication	Inflammation is an important feature of atherosclerotic lesions, and the vulnerability of coronary lesions in acute myocardial infarction (AMI) at the time of onset may be related to blood levels of C-reactive protein (CRP) on admission, before CRP levels are affected by myocardial damage.	10925350
Inflammation, Hemorrhage	Altered Intercellular Communication	Efficacy was assessed by time to relapse (defined as rectal bleeding or increase in stool frequency for > or =1 wk and active inflammation upon endoscopy).	10925979
Fibrous, Inflammation	Altered Intercellular Communication	Biopsy specimens from infected cases showed bone and cement surrounded by either fibrous tissue or acute inflammation without extensive bone apposition.	10926236
Inflammation, Fibrosis Assessment, Cerebral Infarction, Cerebrovascular accident	Altered Intercellular Communication	Because both cytokines are central to the processes of angiogenesis, tissue inflammation, and fibrosis, we performed serial measurements of these cytokines in patients with cerebral infarction and determined their relationship to stroke etiology and volume.	10926948
Vasculitis, CTCAE, Balamuthia	Altered Intercellular Communication	The initial brain biopsy specimen and analysis of CSF samples did not demonstate amebae, but a second biopsy specimen and the postmortem pathologic examination showed Balamuthia trophozoites surrounded by widespread granulomatous inflammation and vasculitis.	10927804
Abscess, Kimura Disease, Granulomatous inflammation	Altered Intercellular Communication	The histopathological investigation of the subcutaneous mass in the upper arm showed lymph node-like tissue with markedly reactive follicular hyperplasia and eosinophilic abscesses associated with granulomatous inflammation, thus leading to the final diagnosis of Kimura's disease.	10927960
Skin necrosis, Inflammation	Altered Intercellular Communication	Complications resulting from the preoperative radiation comprised of serious inflammation in three patients and skin necrosis in another three.	10928167
Intestinal metaplasia, Inflammation, Gland	Altered Intercellular Communication	Histopathological lesions were graded semi-quantitatively according to the updated Sydney System for activity, chronic inflammation, glandular atrophy and intestinal metaplasia (IM), as well as presence of lymphoid follicles.	10929896
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Increased presence of cells containing transforming growth factor alpha (TGF-alpha) in ulcerative colitis, both during active inflammation and in remission.	10929903
Inflammation, Dysplasia, Ulcerative Colitis	Altered Intercellular Communication	In the present study, we correlated the presence of TGF-alpha in ulcerative colitis with the degree of inflammation and with dysplasia.	10929903
Inflammation, Dysplasia, Ulcerative Colitis, Colitis	Altered Intercellular Communication	Sixty two patients were investigated, 46 with ulcerative colitis (16 with active inflammation and 20 in remission, 10 with dysplasia of the colon), and 16 controls with normal colonoscopy and without a history of colitis.	10929903
Dysplasia, Ulcerative Colitis	Altered Intercellular Communication	The median number of TGF-alpha-containing cells in the mucosa was 24 per mm2 (inter-quartile range 10-51) in controls, 186 per mm2 (73-245) in ulcerative colitis with active inflammation, 76 per mm2 (52-198) in remission, and 130 per mm2 (66-203) in areas of dysplasia.	10929903
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The presence of TGF-alpha-containing cells in colonic mucosa is increased both in active inflammation and during remission in ulcerative colitis.	10929903
Microorganism, Vitreous inflammatory cells	Altered Intercellular Communication	Considerable vitreous inflammation can occur with microbial keratitis in the absence of histologically demonstrable microorganisms in the vitreous.	10929976
Inflammation	Altered Intercellular Communication	Macroscopic and microscopic findings showed chronic moderate inflammation of the appendix and rectum.	10930385
Inflammation, Damage	Altered Intercellular Communication	The close localization to the areas containing inflammation (activation of macrophage/microglia) is striking and suggests that axonal damage is closely associated with inflammation in active-chronic lesions.	10930590
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	As considerable differences were found between UC and CD with comparable stages of inflammation, the mere presence of inflammation cannot solely explain the results.	10931137
Intestinal metaplasia, Mucous Membrane, Stomach Carcinoma, Inflammation	Altered Intercellular Communication	Additionally, by histopathological comparison between intestinal (18 cases) and diffuse (70 cases) types of young gastric cancer patients, mucosal atrophy and intestinal metaplasia were found to coexist with acute and chronic inflammation in the background mucosa of both intestinal and diffuse types, being significantly more prevalent than in young controls.	10931235
Inflammation, Myocardial Ischemia	Altered Intercellular Communication	Inflammation is an important component of ischemic heart disease.	10931803
Cerebral Contusion, Contusions, Traumatic injury, Cessation of life, Respiration Disorders	Altered Intercellular Communication	The most common determined causes of death were: cerebral contusions (30), exsanguination (22), respiratory disorders (9), combustion (6), spinal cord contusions (1), and others (complication of injuries, such as inflammations or sepsis--4).	10932616
Weight Gain, Inflammation	Altered Intercellular Communication	Fibrinogen, other putative markers of inflammation, and weight gain in middle-aged adults--the ARIC study.	10933303
Weight Gain, Inflammation	Altered Intercellular Communication	Our aim was to investigate whether inflammation predicts the development of weight gain in populations.	10933303
Weight Gain, Inflammation	Altered Intercellular Communication	Fibrinogen and other putative markers of inflammation predict weight gain in middle-aged adults.	10933303
Communicable Diseases, Inflammation	Altered Intercellular Communication	Increases in ESR are related to the acute phase response in states of inflammation and infection.	10933367
Asthma	Altered Intercellular Communication	The effect of volume history on forced expiratory flow rates has been reported to differ between patients with asthma and healthy persons, and it has been hypothesized that the peripheral airway inflammation of patients with asthma may underlie this difference.	10934066
doxorubicin/fluorouracil protocol, Tumor necrosis, Inflammation, Alveolitis	Altered Intercellular Communication	Fibrosing alveolitis (FA) is characterized by persistent inflammation and elevated production of tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL-1beta), and interleukin-1 receptor antagonist (IL-1ra) in the lung.	10934117
Fibrosis Assessment	Altered Intercellular Communication	Patients with elevated serum GGT had significantly higher serum levels of alanine and aspartate aminotransferases, alkaline phosphatase and total bilirubin, significantly higher histologic scores of liver lobular necro-inflammation and fibrosis when compared to patients with normal serum GGT.	10934805
Hemorrhage, Obstruction, Inflammatory disease of mucous membrane	Altered Intercellular Communication	They are typified by chronic mucosal inflammation, obstruction, bleeding, and occasionally septal perforation--signs and symptoms that are common to many disease states of the nose.	10935304
Achalasia, Inflammation	Altered Intercellular Communication	Previous studies evaluating esophagomyotomy and esophageal resection specimens have shown the presence of myenteric inflammation to be a consistent and early pathologic change in patients with achalasia.	10935657
Inflammation, Squamous metaplasia, Ulcer	Altered Intercellular Communication	Squamous metaplasia of the stomach is a rare clinical entity that occurs during healing of gastric ulcers or chronic inflammation.	10935797
Axonal degeneration, Inflammation	Altered Intercellular Communication	The most significant bioptic results were axonal degeneration and perivascular inflammation.	10935841
Infection caused by Helicobacter pylori, Atrophy of mucosa of stomach, Inflammatory disease of mucous membrane	Altered Intercellular Communication	H. p. infection seemed to cause changes in mucosal condition, severity of gastric mucosal inflammation and gastric mucosal atrophy at all 4 of Sano's points.	10938593
Inflammation, Myopathy	Altered Intercellular Communication	Muscle biopsy revealed a necrotising myopathy with no evidence of inflammation.	10938615
Inflammation, Calculi	Altered Intercellular Communication	Ultrasonography revealed the tract adjacent to an area of inflammation containing a calculus, whereas CT failed to depict the stone.	10939491
Colitis	Altered Intercellular Communication	As butyrate enemas may be beneficial in treating colonic inflammation, we investigated if butyrate promotes this effect by acting on proinflammatory cytokine expression.	10940278
Ulcerative Colitis, Colitis	Altered Intercellular Communication	Mucosal 5-aminosalicylic acid concentration inversely correlates with severity of colonic inflammation in patients with ulcerative colitis.	10940280
Inflammation	Altered Intercellular Communication	5 (3.5-17.4), respectively) and in patients with lower histological inflammation compared with those with more severe scores (17.4 (10.	10940280
Hypothalamic Dysfunction Syndromes	Altered Intercellular Communication	The pattern of hormonal responsiveness suggests that CH encompasses findings typical of primary anterior pituitary disease and those of hypothalamic dysfunction.	10941429
Nasal Polyps	Altered Intercellular Communication	Nasal polyps develop in the ethmoidal and middle turbinate area, often in relation to inflammatory conditions.	10942140
Inflammation, Necrosis, Fibrosis Assessment, Fatty degeneration, Hepatitis C, Chronic, Carcinogenic Chlorinated Hydrocarbon, Damage, Hepatitis, Chronic	Altered Intercellular Communication	Histologic determinants of monoethylglycinexylidide formation in patients with chronic hepatitis C. Patients affected by chronic hepatitis C (CHC) display a peculiar histologic picture characterized by the presence of steatosis and bile duct damage in addition to evidence of inflammation, necrosis, and fibrosis.	10942187
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	The authors found that MEGX15 better reflected the histologic findings of necrosis and inflammation, and MEGX60 the presence of fibrosis.	10942187
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Stepwise regression analysis identified necrosis and inflammation as histologic variables associated with both MEGX15 and MEGX30, and fibrosis as a variable associated with MEGX60.	10942187
Inflammation, Helicobacter pylori, Angina, Unstable, Chlamydia, Acute myocardial infarction	Altered Intercellular Communication	Effect of prior exposure to Chlamydia pneumoniae, Helicobacter pylori, or cytomegalovirus on the degree of inflammation and one-year prognosis of patients with unstable angina pectoris or non-Q-wave acute myocardial infarction.	10946028
Inflammation, Acute Coronary Syndrome, Chronic infectious disease	Altered Intercellular Communication	Inflammation and chronic infections may be important features in the pathogenesis of acute coronary syndromes.	10946028
Inflammation, Angina, Unstable, Chronic infectious disease, Non Q Wave Myocardial Infarction by ECG Finding	Altered Intercellular Communication	We describe 6 systemic markers of inflammation in patients with unstable angina or non-Q-wave myocardial infarction and the relations between these markers, seropositivity to chronic infections, and prognosis.	10946028
Intraocular inflammation	Altered Intercellular Communication	A 52-year-old Saudi man developed intraocular inflammation 7 weeks after uneventful phacoemulsification with implantation of a silicone posterior chamber intraocular lens (IOL).	10946205
Amino Acids, Essential, Neurologic Dysfunction	Altered Intercellular Communication	It is possible that the decrease in plasma concentrations of LNAA may lead to a deficit of these essential amino acids in the brain as well as of their products such as proteins and neurotransmitters, a fact that might be related to the neurological dysfunction of MSUD.	10947205
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic airways inflammation in chronic obstructive pulmonary disease (COPD) induces the activation of several cell types with delivery of proteases and reactive oxygen species (ROS).	10948662
ARCN1 gene, Airway structure	Altered Intercellular Communication	Assessing oxidant content in the exhaled air of COPD patients has proven useful in monitoring airway inflammation.	10948662
allergic inflammation	Altered Intercellular Communication	Evidence has now accumulated that heparin can significantly affect immune response including allergic inflammation.	10948710
Inflammation, Cataract, Senile cataract, PHEX gene, Exfoliation Syndrome	Altered Intercellular Communication	Patients with pseudoexfoliation syndrome (PEX) are known to have a greater degree of inflammation after cataract surgery when compared to patients with senile cataract in otherwise healthy eyes.	10949811
Celiac Disease, Inflammation, Syndrome, Villous atrophy	Altered Intercellular Communication	In patients with the microscopic colitis syndrome, serological tests for celiac sprue were weakly positive in 17%; mild inflammation of the small intestine without villous atrophy was present in 43%, and inflammation plus partial or subtotal villous atrophy was present in 27%.	10950045
Syndrome, Villous atrophy	Altered Intercellular Communication	Mild to moderate mononuclear cell inflammation of the small intestine, often accompanied by partial or subtotal villous atrophy, is frequent in patients with the microscopic colitis syndrome.	10950045
Retinitis	Altered Intercellular Communication	Therefore, a positive result obtained in a patient presenting with vitreoretinal inflammation should be regarded as significant.	10950418
Inflammation, Tuberculosis, Communicable Diseases, Fibrosis Assessment, Pleura, Postcardiac injury syndrome, Rheumatoid Arthritis, Empyema	Altered Intercellular Communication	For this purpose we analyzed 71 histological samples of inflammatory and fibrotic pleura from patients with asbestos-induced pleural reaction (n = 6), postcardiac injury syndrome (n = 6), parapneumonic infection and/or empyema (n = 23), tuberculosis (n = 5, rheumatoid disease (n = 1), and fibrosis with inflammation of unknown etiology (n = 30).	10950882
Airway structure	Altered Intercellular Communication	The collection of induced sputum provides a non-invasive method of investigating airway inflammation.	10950896
Airway structure, Asthma	Altered Intercellular Communication	Overall, there was no correlation between any marker of airway inflammation and asthma severity, however expressed, including lung function.	10950896
Airway structure, Asthma	Altered Intercellular Communication	Sputum analysis revealed no evidence of airway inflammation in a number of highly symptomatic children with asthma.	10950896
Refractory anemias, Inflammation	Altered Intercellular Communication	IL-1ra has proved its therapeutic value in RA, but with the dose schedule in this study it does not behave as a specific radiopharmaceutical that is suitable for scintigraphic detection of inflammation.	10952741
Candida albicans, Inflammation	Altered Intercellular Communication	Candida albicans was isolated from middle ear inflammation.	10953558
Communicable Diseases, Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Infection and inflammation have been suggested to play roles in coronary artery disease (CAD).	10955367
Inflammation	Altered Intercellular Communication	We hypothesized that: (1) CAD risk is associated with the aggregate number of pathogens (pathogen burden), and (2) increased pathogen burden is associated with elevated levels of C-reactive protein (CRP), a marker of inflammation.	10955367
Wheezing, Eosinophilic inflammation	Altered Intercellular Communication	Eosinophilic airways inflammation forms the pathophysiologic basis for a proportion of children at risk of developing recurrent wheezing.	10955705
Airway structure, Respiratory Tract Infections	Altered Intercellular Communication	The use of gas stoves has been associated with respiratory symptoms of chronic airway inflammation and higher rates of respiratory infections.	10956587
Fibrous, Inflammation, Necrosis	Altered Intercellular Communication	In morphologically unstable plaques, there was preferential distribution of F2 within regions of fibrous cap inflammation and/or foam cell accumulation and within abluminal necrotic cores.	10957664
Chronic infectious disease, Inflammation, Myocardial Ischemia, Atherosclerosis	Altered Intercellular Communication	Chronic infection and inflammation have recently been implicated as important etiologic agents for atherosclerosis in general and, in particular, ischemic heart disease.	10957885
Inflammation, Helicobacter pylori, Chlamydia	Altered Intercellular Communication	Several agents have been suggested as possible candidates for the chronic inflammation including cytomegalovirus, Helicobacter pylori and Chlamydia pneumoniae.	10957885
Inflammation	Altered Intercellular Communication	The present study may open a promising perspective concerning future therapeutic trials of chronic inflammation related atherogenesis under pathophysiological conditions.	10957885
Inflammation, Postoperative Complications	Altered Intercellular Communication	Routine atropine use after trabeculectomy may not be necessary to reduce postoperative complications, such as shallowing of the anterior chamber or anterior chamber inflammation.	10958603
Venous Insufficiency, Venous Thromboembolism, Traumatic injury, Neoplasms	Altered Intercellular Communication	acute arterial and venous thrombo-embolism, chronic venous insufficiency of lower limbs, active infections or inflammatory conditions, neoplasms, recent trauma or surgery.	10959145
Diarrhea, Acute biphenotypic leukemia, Gastrointestinal inflammation, Intestinal Graft Versus Host Disease	Altered Intercellular Communication	A 22-month-old boy suffered grade 4 intestinal GVHD, with profuse diarrhea, intestinal inflammation, and grossly bloody stools after matched, unrelated donor transplant for biphenotypic leukemia.	10959906
Gingivitis, Attachment (action), palladium, Periodontitis	Altered Intercellular Communication	The present results suggest that the clinical parameters associated with attachment loss differ between generations and that gingival inflammation is likely associated with the onset of periodontitis more strongly than progression of periodontitis, whereas PD and/or AL are associated with the progression of periodontitis.	10960011
Coughing, Inflammation, Rhinorrhea, Fever, CTCAE	Altered Intercellular Communication	Acute inflammation of the upper airways (URI) was assessed, defined by the presence of at least two of the following symptoms, rhinorrhea, coughing, pharyngodynia, disphony, fever, malaise.	10961056
Stomach Carcinoma, Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Gastric mucosal inflammation and epithelial cell turnover are associated with gastric cancer in patients with Helicobacter pylori infection.	10961177
Granulomatous inflammation, Hypertrophy	Altered Intercellular Communication	Because of the large number of joint prostheses world wide, it should be kept in mind that migration of wear particles can create granulomatous inflammation and node enlargement.	10961180
Inflammation, Rheumatoid Arthritis, Destruction (action)	Altered Intercellular Communication	[Magnetic resonance imaging as a marker of inflammation, destruction and prognosis in rheumatoid arthritis wrists].	10962915
Inflammation, Periprosthetic Fractures, Necrosis	Altered Intercellular Communication	The absolute number and relative proportion of lymphocytes bearing CD2, CD3, CD4, CD8, CD16, CD19, HLA-DR, kappa and lambda antigens were compared with the levels of IL-1beta, IL-6 and PGE2 in the pseudosynovial membrane as well as with a semiquantitative estimate of metal and polyethylene particles, necrosis and chronic inflammation and the total concentration of metals within the periprosthetic tissues.	10963179
Inflammation	Altered Intercellular Communication	Pathologically, the lesion consisted of a larva surrounded by three layers of inflammation: an inner epithelioid granulomatous cell layer, middle chronic inflammatory cell layers, and an outer fibrous layer.	10963426
Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is a form of an inflammatory condition in which the immune system has been shown to be involved.	10963807
Ischemia, Inflammation	Altered Intercellular Communication	We hypothesized that the serum VEGF level is associated with preinfarction ischemia and the increase in VEGF and HGF on day 7 of AMI may represent a response to acute inflammation.	10965088
Inflammation, Leucocytic infiltrate	Altered Intercellular Communication	In two cases with active-chronic inflammation in the spinal cord, perivascular inflammatory infiltration was also seen in the brain, and the composition of cell subsets was similar both in the spinal cord and in the brain.	10965793
Inflammation, Fibrosis Assessment, Edema	Altered Intercellular Communication	Histopathologic examination revealed submucosal and subserosal edema (n = 6), chronic inflammation and fibrosis (n = 5), or both (n = 1), and no histopathologic alteration (n = 1).	10966699
Inflammation, Scleritis, Glaucoma, CTCAE, Episcleritis	Altered Intercellular Communication	22 eyes of 20 consecutive patients with inflammatory, medically uncontrollable, glaucoma secondary to chronic uveitis/trabeculitis (n = 18), chemical injury (n = 2), episcleritis (n = 1), and necrotising scleritis with inflammation (n = 1) were treated by TDLC.	10966953
Cataract, Inflammation	Altered Intercellular Communication	Anterior chamber inflammation is more prolonged after cataract surgery than after trabeculectomy.	10966966
Intraocular inflammation, Retinal Vasculitis	Altered Intercellular Communication	None of the patients developed retinal vasculitis or intraocular inflammation.	10967070
Acute inflammation, Liver Cirrhosis	Altered Intercellular Communication	Approximately 37% of the patients had evidence of active hepatic inflammation or cirrhosis.	10967272
Meckel Diverticulum	Altered Intercellular Communication	[Meckel's diverticulum in a 17-year-old boy as a cause of intermittent chronic pain in the umbilical area and the development of sudden abdominal inflammation--case report].	10967673
Tuberculosis, Pulmonary Emphysema, Neoplasms	Altered Intercellular Communication	In 703 cases (29%) coexistence of emphysema bullosa was found, in 524 cases (22%)--a past tuberculosis lesions, in 42 cases--neoplasm, in 589 cases (20%)--inflammation of the respiratory system.	10967898
Inflammation, Perforation (observation)	Altered Intercellular Communication	Inflammation and perforation of the nasal septum was found on examination of his upper respiratory tract.	10968148
Inflammation, Anemia, idarubicin	Altered Intercellular Communication	Those found to be anaemic were compared with seven age-matched subjects with iron deficiency anaemia (IDA) and 24 age-matched children without signs of anaemia or inflammation.	10968236
Peripheral motor neuropathy, Hajdu-Cheney Syndrome	Altered Intercellular Communication	He had typical physical and radiographic features of Hajdu-Cheney syndrome associated with growth hormone (GH) deficiency and peripheral motor neuropathy.	10968485
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Platelets play an important role in inflammation and are activated in inflammatory bowel disease.	10971234
Inflammation, Asthma	Altered Intercellular Communication	Airways inflammation is a central feature of bronchial asthma and is characterized by the accumulation of eosinophils.	10971470
Inflammation	Altered Intercellular Communication	We suggest that the downregulation of mucosal inflammation consequent on reduction in antigen levels or removal of downregulation after eradication of H. pylori contributes to this shift in cytokine balance.	10971677
Inflammation, Trauma, Nervous System	Altered Intercellular Communication	1H-MRS offers a noninvasive approach to assessing neuronal injury and inflammation following TBI, and may provide unique data for patient management and assessment of therapeutic efficacy.	10972240
Peripheral Nervous System, millicurie, Lichen Planus, Oral, Inflammation	Altered Intercellular Communication	The peripheral nervous system was analysed in the oral mucosa of eight patients with oral lichen planus (OLP), five with a lichenoid reaction (LR) and three with mild chronic inflammation (MCI), by morphometric analysis of nerve fibres containing immunoreactive PGP 9.5, substance P (SP), calcitonin gene-related peptide (CGRP), vasoactive intestinal polypeptide (VIP), or C-flanking peptide of neuropeptide Y (CPON).	10972344
Inflammation	Altered Intercellular Communication	Retraction and local loss of innervation were found in areas coinciding with the most severe inflammation and basal membrane (BM) damage.	10972344
Inflammation	Altered Intercellular Communication	A higher rate of E. faecalis was detected and these eyes had severe inflammation and poor visual outcome.	10974303
Arteriosclerosis, Carcinoma, Atherosclerosis, Elastoid degeneration, Atrophic, Nephrosclerosis, Benign prostatic hypertrophy, Prostatic Intraepithelial Neoplasias, Hyperplasia	Altered Intercellular Communication	Presence of elastosis correlated with the following variables: age, prostatic atrophy (simple, hyperplastic, or sclerotic), local arteriosclerosis, histologic carcinoma, high-grade prostatic intraepithelial neoplasia, benign or malignant nephrosclerosis, generalized atherosclerosis, nodular prostatic hyperplasia, and acute inflammation.	10975927
Carcinoma, Atherosclerosis, Nephrosclerosis, Benign prostatic hypertrophy, Prostatic Intraepithelial Neoplasias	Altered Intercellular Communication	There was no significant relation to histologic carcinoma, high-grade prostatic intraepithelial neoplasia, benign or malignant nephrosclerosis, generalized atherosclerosis, nodular prostatic hyperplasia, and acute inflammation.	10975927
Inflammation	Altered Intercellular Communication	There therefore seems to be a close relation between NO, oxidative stress, regulation of growth and inflammation.	10976827
Inflammation, Traumatic injury	Altered Intercellular Communication	Proinflammatory cytokines play an important role in the mediation of inflammation and trauma.	10978634
Inflammation, Hyphema, Hypesthesia	Altered Intercellular Communication	Slit-lamp examination demonstrated hyphema, anterior chamber inflammation, mid-dilated pupil, impaired corneal sensation, and high intraocular pressure, without any facial skin lesions.	10980684
Atrophic iris, Corneal sensation, Bladder Sphincter Dysfunction, Intraocular inflammation	Altered Intercellular Communication	Typical sectorial iris atrophy with pupillary sphincter dysfunction and complete loss of corneal sensation developed after the resolution of intraocular inflammation.	10980684
Inflammation, Hydrocephalus	Altered Intercellular Communication	Postgadolinium magnetic resonance imaging demonstrated enhancement of basilar and cervical meninges, suggesting inflammation, and communicating hydrocephalus.	10981768
Fibrous, Inflammation, Cleft ala nasi	Altered Intercellular Communication	Deep clefts, sinuses, dense fibrous scars and foci of chronic inflammation were seen.	10982024
Hepatic inflammation, Hepatitis C	Altered Intercellular Communication	The majority of the patients were diagnosed to have chronic hepatitis C with low activity of hepatic inflammation and frequent (55%) absence of the diagnostic antibodies to hepatitis C virus in the serum.	10983324
Airway structure, Symptoms	Altered Intercellular Communication	However, it is important that inhaled corticosteroid therapy is still given at a dose high enough to control airway inflammation as well as asthma symptoms.	10983616
Inflammation, Fracture, Diabetes Mellitus	Altered Intercellular Communication	Screening for older patients who are not disabled but have poor lower extremity performance selects a subgroup of the population with a high percentage of women, high prevalence of diabetes and hip fracture, and high levels of biological markers of inflammation.	10983911
ER-overload response, Joint structure of shoulder region	Altered Intercellular Communication	Ultrasound examination revealed glenohumeral joint inflammation in 40.9% (9/22) of the patients with PMR and 65.5% (19/29) of the patients with EORA.	10984136
Subdeltoid bursitis, Inflammation, ER-overload response	Altered Intercellular Communication	effusion/synovitis, subdeltoid bursitis and biceps tendon sheath effusion were more frequent in patients with EORA, with a predominate symmetry and signs for massive inflammation.	10984136
Inflammation, ER-overload response	Altered Intercellular Communication	The typical ultrasonographic result in patients with PMR was a unilateral inflammation of the glenohumeral joint with predominate discrete biceps tendon sheath effusion and, in comparison with the EORA group, with signs of a low grade inflammation.	10984136
Inflammation, Sideroblastic anemia, Anemia, Malignant Neoplasms, Thalassemia	Altered Intercellular Communication	In the differential diagnosis of hypochromic-microcytic anemia, especially in postmenopausal women, one has to consider this type of treatable anemia when more common types such as iron deficiency, chronic inflammation, malignancy, sideroblastic anemia, or thalassemia have been ruled out.	10985370
Polymyositis, Inflammation, Necrosis	Altered Intercellular Communication	In polymyositis, SSB-positive myonuclei were observed in regenerating fibers and muscle fibers in the vicinity of inflammatory infiltrates, suggesting that the increase of SSB is due to muscle fiber regeneration following necrosis and inflammation.	10985697
Inflammation, Myopathy, Necrosis	Altered Intercellular Communication	In muscle diseases with RV, however, SSB-positive myonuclei were observed in small angulated fibers and in morphologically normal fibers, regardless of necrosis, regeneration or inflammation.	10985697
Inflammation, Pregnancy Complications, Infectious	Altered Intercellular Communication	Furthermore, Elastase (a decisive marker for inflammation and infectious complications) was found to be higher in patients being pronounced in day 2 than in day 1 (day 1 [200 +/-136], day2 [139 +/-118]).	10985928
Inflammation, Ulcerative Colitis, Rectum and sigmoid colon, Ichthyosis Bullosa of Siemens, Hypersensitivity, Inflammatory disease of mucous membrane	Altered Intercellular Communication	In this study we compared perceptual responses to rectosigmoid distension in patients with mild chronic inflammation of the rectum (ulcerative colitis (UC)) and patients without mucosal inflammation (IBS) to determine if chronic low grade mucosal inflammation may be a plausible explanation for rectosigmoid hypersensitivity reported in both IBS and UC patients.	10986209
Inflammation, Hyperalgesia	Altered Intercellular Communication	In chronic mild inflammation, activation of antinociceptive mechanisms may prevent the development of visceral hyperalgesia.	10986209
Inflammation, Gastrointestinal Diseases	Altered Intercellular Communication	Low grade mucosal inflammation alone is unlikely to be responsible for symptoms in functional gastrointestinal disorders.	10986209
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	A simple method for assessing intestinal inflammation in Crohn's disease.	10986210
Gastrointestinal inflammation	Altered Intercellular Communication	Assessing the presence and degree of intestinal inflammation objectively, simply, and reliably is a significant problem in gastroenterology.	10986210
Pancreatitis, Acute, Pancreatitis, Organ Dysfunction Scores	Altered Intercellular Communication	The time course and relationship between circulating and local cytokine concentrations, pancreatic inflammation, and organ dysfunction in acute pancreatitis are largely unknown.	10986216
Inflammation, Hemorrhage, Obstruction	Altered Intercellular Communication	Symptoms normally occur only when there are complications, when bleeding, obstruction and inflammation are most frequent.	10986608
Inflammation, Pain Distress Question	Altered Intercellular Communication	Positive physical findings were often limited to inflammation in the vestibule (25%) and pain on palpation of the posterior vestibule (69%).	10986689
Inflammation, Blood Clot	Altered Intercellular Communication	Microscopic evaluation showed only organized thrombus but no evidence of inflammation in the mitral valve.	10987358
Pain Distress Question, Inflammation	Altered Intercellular Communication	Benzodiazepines and their receptors play key roles in pain, in interactions with peptide opioids, in inflammation and in the response to stress.	10987594
Inflammation	Altered Intercellular Communication	This increased incidence may be related to an increase in pigment deposition complexed with collagen during the remodeling process, subclinical inflammation, or glucocorticosteroid-induced skin fragility.	10987869
Inflammation, Atherosclerosis, Coronary heart disease	Altered Intercellular Communication	Since atherosclerosis is a chronic inflammation and the erythrocyte sedimentation rate is an appropriate test for monitoring chronic inflammatory responses, we wanted to investigate whether the erythrocyte sedimentation rate might carry prognostic information on the risk of sustaining coronary heart disease events.	10988014
Airway structure, Bronchitis	Altered Intercellular Communication	Our hypothesis was that the differences in airway pathophysiology maybe due to less active airway inflammation in eosinophilic bronchitis, with reduced release of important effector mediators.	10988099
Airway structure, Bronchitis	Altered Intercellular Communication	In conclusion, eosinophilic bronchitis is associated with active airway inflammation with increased release of vasoactive and bronchoconstrictor mediators.	10988099
Cataract, Inflammation	Altered Intercellular Communication	Diclofenac drops to treat inflammation after cataract surgery.	10990044
Pneumonitis	Altered Intercellular Communication	Reduced IL-12 levels may contribute to the development of asthmatic pulmonary inflammation through dysregulation of Th cell development.	10992536
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation and activation of immune cells have important roles in the pathogenesis of atherosclerosis.	10992723
Ocular melanosis, melanoma, Squamous cell carcinoma, Esophagitis, Hyperplasia	Altered Intercellular Communication	While melanocytic hyperplasia (melanocytosis) has previously been recognized as an occasional reactive lesion that can accompany esophageal inflammation and invasive squamous carcinoma, the present case was unusual because of its cytonuclear and architectural atypia in the melanocytic cell population, resembling features of a melanoma in situ in the absence of manifest invasive malignant melanoma.	10993284
Crohn Disease, Inflammation	Altered Intercellular Communication	In Crohn's disease (CD), labeled leukocyte scintigraphy results are highly correlated with radioendoscopic findings and the degree of histologic inflammation.	10993433
Inflammation	Altered Intercellular Communication	The presence of IL-10 in middle ear effusions may be one of the causes of a lack of clinical features of acute inflammation and may lead to a chronic inflammatory state.	10993552
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Apart from two (both from HBsAg carriers) with normal histology, all liver biopsies manifested various degrees of inflammation and fibrosis.	10994626
Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	Inflammation is associated with carotid atherosclerosis in dialysis patients.	10994751
Inflammation, Atherosclerosis	Altered Intercellular Communication	These data lend support to the hypothesis that inflammation plays a role in the pathogenesis of atherosclerosis in these patients.	10994751
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	It is known that eosinophils are actively involved in allergy and inflammation.	10994770
Inflammation	Altered Intercellular Communication	ECP and EDN/EPX could thus be released to the local tissue and modulate the inflammation of the prurigo nodularis lesion.	10994770
Inflammation, Erosion of bone	Altered Intercellular Communication	Open transantral biopsy was done under general anesthesia, revealing severe inflammation in the right maxillary sinus as well as bone erosion.	10996238
Airway structure, Bronchitis	Altered Intercellular Communication	Association between airway bacterial load and markers of airway inflammation in patients with stable chronic bronchitis.	10996579
Airway structure	Altered Intercellular Communication	We hypothesized that the number of organisms and bacterial species might be important modulators of airway inflammation.	10996579
Airway structure	Altered Intercellular Communication	The results were related to several indicators of the mechanisms and severity of airway inflammation.	10996579
Inflammation	Altered Intercellular Communication	Markers of inflammation increased at bacterial loads of 10(6) to 10(7) colony-forming units per milliliter, and increased progressively with increasing bacterial load.	10996579
Airway structure, Pseudomonas aeruginosa	Altered Intercellular Communication	The bacterial species influenced airway inflammation; for example, sputum myeloperoxidase activity was greater (P<0.005) in patients colonized with Pseudomonas aeruginosa [median 32 U/mL (interquartile range, 20 to 65 U/mL)] than those colonized with nontypeable Hemophilus influenzae [4 U/mL (2 to 31 U/mL)], which in turn was greater (P = 0.01) than among those colonized with Moraxella catarrhalis [1.1 U/mL (0.6 to 1.8 U/mL)].	10996579
Airway structure, Bronchitis	Altered Intercellular Communication	The bacterial load and species contribute to airway inflammation in patients with stable chronic bronchitis.	10996579
Inflammation, allergic symptom	Altered Intercellular Communication	Our epidemiological data suggest that whether low levels of specific IgE to indoor allergens lead to allergic symptoms is probably determined by the concurrent existence of inflammation of the airways.	10998014
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The aim of this study was firstly to examine whether tHcy is associated with endothelial dysfunction, increased adherence of leukocytes, and/or chronic low-grade inflammation, as estimated from plasma levels of von Willebrand factor (vWf), soluble vascular cell adhesion molecule 1 (sVCAM-1) and C-reactive protein (CRP), respectively.	10998075
Inflammation	Altered Intercellular Communication	tHcy was not significantly associated with chronic low-grade inflammation as estimated from plasma CRP.	10998075
Airway structure, Rhinovirus infection	Altered Intercellular Communication	These events may be important for the spread of airway inflammation after rhinovirus infection.	10998927
Airway structure, Rhinovirus infection	Altered Intercellular Communication	These findings in our in vitro study suggest that dexamethasone, erythromycin and bafilomycin A1 may inhibit rhinovirus infection and modulate airway inflammation induced by rhinovirus infection.	10998927
Inflammation, Asthma	Altered Intercellular Communication	Secondary outcome measures were inflammation markers in serum, and parameters of asthma control.	10999872
Inflammation	Altered Intercellular Communication	Increased homocyst(e)ine associated with smoking, chronic inflammation, and aging may reflect acute-phase induction of pyridoxal phosphatase activity.	11000053
Inflammation, Blood Clot	Altered Intercellular Communication	At reoperation, inflammation was a prominent feature at the vessel site of thrombi.	11000072
Mycobacterium Infections, Granulomatous inflammation	Altered Intercellular Communication	Characteristic histopathologic findings of mycobacterial infection including caseation, granulomatous inflammation, eosinophilic epithelioid cells, Langhan's giant cells, and lymphocytic aggregates were noted in all 15 patients.	11000735
Airway structure, Tumor necrosis, Chronic Obstructive Airway Disease, ARCN1 gene	Altered Intercellular Communication	The cytokines that contribute to airway inflammation, including interleukin-1beta (IL-1beta) and tumour necrosis factor alpha (TNFalpha), might have key roles in the development of chronic obstructive pulmonary disease (COPD).	11001075
Saccular Aneurysm, Inflammation	Altered Intercellular Communication	Although the inflammation was resolved, saccular aneurysms in the aortic arch and thoracoabdominal aorta enlarged rapidly.	11002581
Inflammation	Altered Intercellular Communication	Despite the drainage, signs of inflammation persisted and the patient's nutrition did not improve leading to surgery, on August 18, 1997.	11002589
Inflammation, Helicobacter pylori, Pancreatic aplasia, Intestinal metaplasia, Foveolar hyperplasia	Altered Intercellular Communication	Biopsies were scored on a visual analogue scale of 0 to 5 for Helicobacter pylori, intestinal metaplasia, pancreatic metaplasia, foveolar hyperplasia, and active inflammation.	11002767
Airway structure, Bronchitis, Chronic, Bronchitis	Altered Intercellular Communication	The results obtained indicate that macrophages and neutrophils present within the airways of chronic bronchitis subjects express 15-LO mRNA; increased basal levels of 15(S)-HETE may contribute to modulate, through the inhibition of 5-lipoxygenase metabolites production, neutrophil infiltration and airway inflammation associated with chronic bronchitis.	11003605
Stevens-Johnson Syndrome, CTCAE, Conjunctivitis	Altered Intercellular Communication	Conjunctival inflammation in the chronic phase of Stevens-Johnson syndrome.	11004109
Inflammatory abnormality of the eye	Altered Intercellular Communication	The ocular inflammation was successfully managed with topical steroids and mydriatics.	11004276
Ocular histoplasmosis syndrome, Granulomatous inflammation, Choroidal Neovascularization	Altered Intercellular Communication	Choroidal neovascularization with granulomatous inflammation in ocular histoplasmosis syndrome.	11004309
Ocular histoplasmosis syndrome, Granulomatous inflammation	Altered Intercellular Communication	To report pathologic examination of an excised choroidal neovascular membrane in a patient with ocular histoplasmosis syndrome that demonstrated granulomatous inflammation.	11004309
Granulomatous inflammation	Altered Intercellular Communication	Histopathologic examination of the surgically excised choroidal neovascular membrane disclosed granulomatous inflammation.	11004309
Granulomatous inflammation, Choroidal Neovascularization	Altered Intercellular Communication	This association of choroidal neovascularization with granulomatous inflammation did not respond to treatment with systemic corticosteroids.	11004309
Infarction, Inflammation, Necrosis, Trauma, Nervous System	Altered Intercellular Communication	Microscopic sections stained with hematoxylin and eosin revealed complete, organizing infarction in 107 cases with areas of coagulative necrosis, anoxic-ischemic neuronal injury, inflammation, macrophages, vascular proliferation, gliosis, and swollen axons.	11005257
Intestinal metaplasia, Inflammation, Malignant Neoplasms, Ulcer	Altered Intercellular Communication	Two sets of conventional biopsies failed to detect malignancy, only inflammation and intestinal metaplasia were seen in the specimens of the mucosa surrounding the ulcer.	11005337
Degenerative polyarthritis, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	In inflammation, COX-2 is induced, causing synthesis of the prostaglandins in conditions such as osteoarthritis and rheumatoid arthritis.	11005360
Inflammation, Refractory anemias, Degenerative polyarthritis, Rheumatoid Arthritis, destruction joint	Altered Intercellular Communication	It has been suggested that it is a surrogate marker of synovial inflammation and joint destruction in rheumatoid arthritis (RA) and osteoarthritis (OA) and related to C reactive protein (CRP) serum levels in RA.	11005786
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The correlation between YKL-40 and CRP suggests that YKL-40 may be a marker of joint inflammation in OA.	11005786
Intraocular inflammation	Altered Intercellular Communication	Ocular samples were also collected from 38 eyes that underwent routine surgery and from 15 eyes with intraocular inflammation due to nonbacterial causes.	11006241
Inflammation, Dental Plaque	Altered Intercellular Communication	However, plaque instability might be caused by pathophysiologic processes, such as inflammation, that exert adverse effects throughout the coronary vasculature and that therefore result in multiple unstable lesions.	11006367
Inflammation, Infection	Altered Intercellular Communication	This association may be partly due to an increase in metabolic risk factors for CVD, secondary to low-grade inflammation caused by infections.	11006888
Inflammation, Atherosclerosis	Altered Intercellular Communication	Whether systemic inflammation is an epiphenomenon of atherosclerosis or whether it is part of the atherosclerosis causal pathway requires further study.	11006900
Pancreatitis, Alcohol abuse, Neoplasms	Altered Intercellular Communication	Chronic alcohol abuse and heavy smoking characterized these patients, and four of them also had pancreatitis, suggesting an association of gastrin-producing tumors and pancreatic inflammation.	11007101
Inflammation, Sarcoidosis, Primary malignant neoplasm	Altered Intercellular Communication	In 101 patients without previous cancer cytology identified 48 malignant (lung, 41; extrathoracic, 7) and 51 benign lesions (inflammation, 35; various, 9; sarcoidosis, 7) (sensitivity, specificity, accuracy: 88%, 100%, 94%).	11007229
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The Mayo risk score did not change significantly, and although a significant improvement in the degree of portal inflammation was noted at the end of the treatment period, the degree of fibrosis and stage of disease were not significantly affected.	11007238
Nephritis, Interstitial, Communicable Diseases, Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation in reponse to infectious agents or drugs in immunosuppressed kidney transplant recipients can rarely give rise to allograft interstitial nephritis that is distinct from acute rejection.	11007702
Inflammation, Depression, CTCAE	Altered Intercellular Communication	The authors investigated this association by determining whether intercellular adhesion molecule-1 (ICAM-1), a marker of ischemia-induced inflammation, is elevated in the dorsolateral prefrontal cortex in depression.	11007725
Cessation of life, Inflammation, Malnutrition, Cardiovascular Diseases	Altered Intercellular Communication	Elevated serum levels of soluble adhesion molecules predict death in pre-dialysis patients: association with malnutrition, inflammation, and cardiovascular disease.	11007832
Inflammation, Edema, Hyperemia	Altered Intercellular Communication	The colonic mucosa demonstrated normal to moderate inflammation as well as hyperemia and edema.	11008724
Pneumonitis, Pneumonia	Altered Intercellular Communication	It is well known that acute pulmonary inflammation, such as that observed in pneumonia, elevates secretory leukoprotease inhibitor (SLPI) levels in serum.	11013357
Inflammation	Altered Intercellular Communication	The expression of adhesion molecules in the sublining layers reflects ongoing inflammation.	11014344
Inflammation, Asthma, Hypocortisolism secondary to another disorder	Altered Intercellular Communication	Inhaled corticosteroids have beneficial effects on pulmonary function and inflammation in patients with asthma, but they also cause systemic adverse effects, such as adrenal suppression.	11014718
Neuronal degeneration, Inflammation, Necrosis, NEUROG1 gene	Altered Intercellular Communication	Brain-stem specimens from 2 patients were available, and both specimens showed extensive neuronal degeneration, inflammation, and necrosis, suggesting that a central nervous system infection was responsible for the disease, with the cardiopulmonary dysfunction being neurogenic in origin.	11017815
Inflammation, Bronchial Hyperreactivity	Altered Intercellular Communication	Bronchial hypersensitivity depends on initial clinical symptoms of BA, in a less degree on bronchial permeability, severity of inflammation of bronchial mucosa.	11019419
Graft-vs-Host Disease, gastrointestinal, Gastrointestinal mucositis	Altered Intercellular Communication	In adults, gastrointestinal (GI) inflammation due to either mucositis or GVHD resulted in a higher AUC of 3077+/-1551 microg x h/l compared to 1795+/-973 microg x h/l (P = 0.02), and a similar trend was observed in children.	11019845
Inflammation, Degenerative disorder, Data types - Address	Altered Intercellular Communication	These results lay the groundwork for further studies on modification and damage associated with the degenerative disorder in AD where oxidative stress and inflammation are known to occur.	11019859
Inflammation	Altered Intercellular Communication	We tested the hypothesis that the depressive symptomatology is associated with a reactivation of latent viruses and inflammation of a coronary vessel.	11020087
Inflammation, Depression, CTCAE	Altered Intercellular Communication	It remains to be seen whether the inflammation causes feelings of exhaustion, whether exhaustion and depression set the stage for inflammation, or whether existing feelings of exhaustion are amplified by the inflammation.	11020087
Shock, Inflammation, Abscess of pancreas, Kidney Calculi	Altered Intercellular Communication	We reported a case of peripancreatic abscess with inflammation change of common bile duct and pancreatic head following extracorporeal shock wave lithotripsy for right renal stone.	11020904
Inflammation, ovarian neoplasm	Altered Intercellular Communication	Factors related to inflammation of the ovarian epithelium and risk of ovarian cancer.	11021606
Inflammation, ovarian neoplasm	Altered Intercellular Communication	We examined these and other risk factors in the context of a new hypothesis: that inflammation may play a role in ovarian cancer risk.	11021606
Oophoritis, Cyst, talc, Hyperthyroidism, Endometriosis	Altered Intercellular Communication	Ovulation entails ovarian epithelial inflammation; talc, endometriosis, cysts, and hyperthyroidism may be associated with inflammatory responses of the ovarian epithelium; gynecologic surgery may preclude irritants from reaching the ovaries via ascension from the lower genital tract.	11021606
Inflammation, ovarian neoplasm	Altered Intercellular Communication	The spectrum of associations provides support for the hypothesis that inflammation may mediate ovarian cancer risk.	11021606
Ischemia, Inflammation, Progressive neurologic deterioration	Altered Intercellular Communication	Several proinflammatory cytokines are released early after the onset of brain ischemia, but it is unknown whether inflammation predisposes to neurological deterioration.	11022058
Arthritis, Gastrointestinal inflammation	Altered Intercellular Communication	HLA-B27 transgenic rats exhibit generalized, severe inflammatory reactions and spontaneously develop arthritis and chronic gastrointestinal inflammation, as well as inflammatory lesions in other tissues.	11022768
Inflammation, Focal necrosis	Altered Intercellular Communication	Oral manifestations include ulcerations of mucous membranes, acute gingival inflammation with focal necrosis, and rapid loss of attachment.	11022781
Hepatitis A, Hepatitis	Altered Intercellular Communication	Hepatitis A virus (HAV) cause an acute inflammation of the liver.	11023059
Inflammation, Atherosclerosis	Altered Intercellular Communication	There is evidence to suggest that inflammation plays a role in the development of atherosclerosis.	11023239
Inflammation, Fibrosis Assessment, Chlamydia Infections, Trachoma	Altered Intercellular Communication	Genes involved in regulating antimicrobial immunity and inflammation may modulate the risk of tissue scarring and fibrosis in chlamydial diseases such as trachoma.	11023480
Refractory anemias, Rheumatoid Arthritis, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	Our objective was to investigate sympathetic and sensory nerve fibers in synovial tissue in rheumatoid arthritis (RA) and osteoarthritis (OA) in relation to histological inflammation and synovial cytokine and norepinephrine (NE) secretion.	11023994
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	In RA, there was a negative correlation between the number of TH-positive nerve fibers and inflammation index (RRank=-0.705, P=0.002) and synovial IL-6 secretion (RRank=-0.630, P=0.009), which was not found in OA.	11023994
Inflammation	Altered Intercellular Communication	The differential patterns of innervation are dependent on the severity of the inflammation.	11023994
Inflammation	Altered Intercellular Communication	This demonstrates a loss of the influence of the sympathetic nervous system on the inflammation, accompanied by an up-regulation of the sensory inputs into the joint, which may contribute to the maintenance of the disease.	11023994
Inflammatory abnormality of the eye, Complication Aspects, Scleritis	Altered Intercellular Communication	Scleritis is a severe ocular inflammation, often associated with ocular complications, and nearly always treated with systemic medications.	11024419
Vasculitis	Altered Intercellular Communication	A satisfactory result can be achieved by using corticosteroids to control the retinal vascular inflammation, by applying panretinal photocoagulation and by controlling the increased intraocular pressure surgically.	11024432
Inflammation, Gastro-esophageal reflux disease with esophagitis, Barrett Esophagus, Malignant neoplasm of esophagus, Hiatal Hernia	Altered Intercellular Communication	118 patients had reflux esophagitis, 36 had Barrett's esophagus, 108 had hiatal hernia without signs of inflammation (the reflux group), and 20 patients had esophageal or stomach cancer.	11025356
Pancreatitis	Altered Intercellular Communication	Activation of trypsinogen and phospholipase A(2) is an early event in pancreatic inflammation, but little is known about zymogen activation and the severity of human pancreatitis.	11025364
Inflammation, Necrosis	Altered Intercellular Communication	Viral load was correlated with necrosis and inflammation (p<0.05).	11025369
Pain Distress Question, Bladder dysfunction	Altered Intercellular Communication	Six months after implantation of a sacral neuromodulator the patient is pain free and significantly improved on bladder dysfunction.	11025436
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	The influence of enhanced postoperative inflammation by the intrapleural administration of streptococcal preparation (OK-432) on the prognosis of completely resected non-small-cell lung cancer.	11025462
malignant disease, Inflammation	Altered Intercellular Communication	It is not clear whether postoperative inflammation affects the prognosis of malignant disease.	11025462
Inflammation, Neoplasms	Altered Intercellular Communication	Based on the above findings, postoperative prolonged inflammation does not seem to affect the progression of subclinically residual tumor cells.	11025462
Vitreous strands	Altered Intercellular Communication	The ocular signs of anterior segment inflammation along with vitreous infiltrate resolved on topical steroid therapy without long-term visual sequelae.	11026997
Inflammation, Pain Distress Question, Synovitis, Fibrosis Assessment, Hypertrophy, Rotator cuff syndrome, Irritation	Altered Intercellular Communication	This had caused a slowly progressive enlargement of the lesion because of fibrosis resulting from reactive inflammation associated with this repetitive microtrauma, thus causing irritation, pain, and synovitis due to impingement.	11027773
Dyspnea, Inflammation, Asthma, ARCN1 gene	Altered Intercellular Communication	This study investigated the possible role of inflammation and the contribution of clinical variables on dyspnoea in subjects with COPD and asthma.	11028665
Airway structure, Inflammation	Altered Intercellular Communication	As adenosine 5'-monophosphate is regarded as an indirect marker of airway inflammation, the results suggest that inflammation is not important because both groups showed similar responses on such provocations.	11028665
Inflammation, Primary Lesion, Neoplasm Metastasis	Altered Intercellular Communication	In cases of intense FDG uptake, differentiation between a primary lesion, a metastasis, and an acute inflammation is often not possible.	11028711
Inflammation, Asthma	Altered Intercellular Communication	Airway and alveolar inflammation have been described in asthma.	11029356
Inflammation	Altered Intercellular Communication	Prolonged inflammation may lead to airway remodeling, which can result in physiologic abnormalities.	11029356
Inflammation	Altered Intercellular Communication	These differences in adhesion molecule expression and fibronectin release may be important in epithelial cell inflammation and repair.	11030373
Hypermanganesemia, Inflammation, Cholestatic liver disease	Altered Intercellular Communication	In HPN patients, sustained inflammation may facilitate hypermanganesemia through 1. cholestatic liver disease and thereby decreased Mn biliary excretion, 2. high nutritional requirements (responsible for increased Mn supply), and/or 3. modified Mn metabolism or body distribution.	11031073
Inflammation	Altered Intercellular Communication	Two months after surgery, there was significantly more inflammation in the silicone IOL group than in the PMMA group (P <.	11033400
Cataract, Inflammation	Altered Intercellular Communication	However, some silicone lenses are associated with an increased risk of recurrence of inflammation and a higher final complication rate in combined cataract and filtration surgery.	11033400
Inflammation, Chronic infectious disease	Altered Intercellular Communication	A forearm plate retained for 50 years was removed because an acute inflammation mimicked chronic infection.	11033921
Interlobular bile duct, Inflammation	Altered Intercellular Communication	Liver biopsy, available in 12 patients, showed perivenular bilirubinostasis, accompanying reactive ceroid laden macrophages, and portal inflammation with focal injury to interlobular bile ducts.	11034591
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	The role of inflammation in coronary artery disease (CAD) is being increasingly recognized.	11034939
Communicable Diseases, Chlamydia, Inflammation	Altered Intercellular Communication	Markers of inflammation (eg, C-reactive protein [CRP]) and infection (eg, seropositivity to Chlamydia pneumoniae, cytomegalovirus [CMV], and Helicobacter pylori) have been proposed as risk factors for CAD, but these associations require further evaluation.	11034939
Refractory anemias, Inflammation	Altered Intercellular Communication	Data from this pilot study suggest that 4162W94 is a clinically active novel immunotherapeutic agent that may suppress inflammation in RA.	11035136
Necrotizing granulomatous inflammation	Altered Intercellular Communication	The periphery of the mass consisted of a thin rim of cortical and medullary adrenal tissue with superimposed granulomatous chronic inflammation.	11035597
Alcoholic Intoxication, Chronic	Altered Intercellular Communication	We postulate that excitatory neurotransmitters and mechanisms of oxidative stress in patients with chronic alcoholism may partly mediate excitotoxic neuronal damage and hereby cause brain shrinkage.	11036188
Crohn Disease, Stenosis, Gastrointestinal inflammation	Altered Intercellular Communication	Intestinal inflammation in Crohn's disease (CD) may be complicated by the occurrence of strictures and fistulae.	11037350
Airway structure, Sinusitis	Altered Intercellular Communication	It is likely that genetic factors play a role in the etiology of chronic sinusitis, and airway inflammation is an important pathological feature in chronic sinusitis.	11037831
Refractory anemias, Inflammation	Altered Intercellular Communication	The results suggest that PG-containing cells may contribute to inflammation within the microenvironment of the joint in RA patients.	11037875
Glucagonoma, insulinoma	Altered Intercellular Communication	Four patients with conspicuously large insulinomas, and three with glucagonoma were successfully operated on with alleviation of hormonal symptoms.	11038206
Inflammation	Altered Intercellular Communication	Patients with visual ischemic complications had lower clinical and laboratory biologic markers of inflammation.	11039076
Tolosa-Hunt Syndrome, Necrotizing granulomatous inflammation	Altered Intercellular Communication	Tolosa-Hunt syndrome is characterized by painful ophthalmoplegia due to idiopathic granulomatous inflammation of the cavernous sinus.	11039176
Tolosa-Hunt Syndrome, Inflammation, Ophthalmoplegia	Altered Intercellular Communication	We report the case of a 78-year-old male patient in whom systemic lymphoma associated with inflammation of the cavernous sinus was uncovered by painful, gradually progressing, ophthalmoplegia mimicking Tolosa-Hunt syndrome.	11039176
Adhesion of pleura, Inflammation, Prevertebral Abscess	Altered Intercellular Communication	Pleural adhesions, owing to local inflammation or paravertebral abscess, were seen in four patients and one patient with severe pleurodesis needed an open technique for treatment.	11039801
Inflammation, Psoriasis	Altered Intercellular Communication	Within 3 weeks, his psoriasis had improved dramatically and his joint inflammation had stabilized.	11040859
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	The best radiological indicators for a positive CT for appendicitis were pericecal inflammation (88%) and appendicolith(57%).	11044529
Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Purpura	Altered Intercellular Communication	Leukocytoclastic vasculitis is a condition characterized by necrotizing neutrophilic inflammation of small dermal blood vessels usually resulting in palpable purpuric lesions.	11044832
Inflammation	Altered Intercellular Communication	Power Doppler ultrasound of gallbladder wall vascularization in inflammation: clinical implications.	11044929
Pain Distress Question, Damage, Inflammation	Altered Intercellular Communication	Pain was significantly related to clinical manifestations of inflammation and articular damage.	11045172
Pain Distress Question, Inflammation	Altered Intercellular Communication	The relationship between pain and laboratory manifestations of inflammation (CRP, FW) was not very close.	11045172
Inflammation, Helicobacter pylori, Gastritis	Altered Intercellular Communication	Helicobacter pylori (HP)-associated gastritis is characterized by an increased number of acute and chronic inflammatory cells secreting cytokines that contribute to maintain and expand the local inflammation.	11046068
Granulomatous inflammation	Altered Intercellular Communication	Pathohystological examination of the lymph mode and cytological examination of the bronchial mucus confirmed granulomatous inflammation.	11048461
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	Cardia inflammation is a stimulus for cardia intestinal metaplasia, and a reduction in inflammation may allow the metaplastic mucosa to revert to normal.	11048800
Inflammation, Skin	Altered Intercellular Communication	Whether or not immature myeloid cell precursors constitute a specific infiltrate of leukemia cutis or are a result of recruitment of circulating leukemic cells to this area of inflammation is discussed.	11048979
Fibrosis Assessment, Portal inflammation, Necrosis	Altered Intercellular Communication	Three factors in the HAI, periportal necrosis, intralobular necrosis, and portal inflammation, but not fibrosis, were significantly decreased in complete responders (p < 0.01) and biochemical responders (p < 0.01).	11049207
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	We hypothesized that inflammation in human inflammatory bowel disease might result from innate alterations in the IL-10 pathway.	11051278
Inflammation	Altered Intercellular Communication	In these cells, activated NF-kappaB may be involved in the inflammation process in HAG through the up-regulation of chemokines or adhesion molecules.	11051346
Proctitis, Chronic diarrhea	Altered Intercellular Communication	Fecal calprotectin levels predict colorectal inflammation among patients with chronic diarrhea referred for colonoscopy.	11051356
Proctitis	Altered Intercellular Communication	Stool testing may serve as a diagnostic aid to discriminate the presence or absence of organic pathology, such as colorectal inflammation.	11051356
Proctitis	Altered Intercellular Communication	Colonoscopic and histological findings served as criterion standards for establishing the presence or absence of colorectal inflammation.	11051356
Proctitis	Altered Intercellular Communication	Among 110 subjects who provided complete fecal assay data, 29 (26%) had and 81 (74%) did not have colorectal inflammation.	11051356
Proctitis	Altered Intercellular Communication	Increased fecal calprotectin levels were significantly (p = 0.0001) associated with the presence of colorectal inflammation, whereas fecal hemoglobin levels were not (p = 0.61).	11051356
Proctitis	Altered Intercellular Communication	Direct comparison of the fecal assays revealed that calprotectin was a more sensitive biomarker for colorectal inflammation at all specificity levels (p = 0.0001).	11051356
Inflammation, Perfusion (biological)	Altered Intercellular Communication	The grade of localized hyperperfusion of the knee region in the blood pool phase of 99mTc HDP bone scan indicating inflammation did not correlate with any elemental concentration determined.	11051615
Inflammation	Altered Intercellular Communication	From these findings we suggest that a lichenoid inflammation may be responsible for the typical maculo-papular lesions of DDD.	11052235
Inflammation, Diverticulitis	Altered Intercellular Communication	Diverticulitis was considered moderate when computed tomography showed localized thickening of the colonic wall (5 mm or more) and inflammation of pericolic fat and contrast enema showed segmental lumen narrowing and tethered mucosa; it was considered severe when abscess or extraluminal air or contrast or all three were observed on computed tomography and when one or both of the last two signs were seen on contrast enema.	11052512
Inflammation, Diverticulitis	Altered Intercellular Communication	The performance of computed tomography was significantly superior to contrast enema in terms of sensitivity (98 vs. 92 percent; P = 0.01), which was calculated from patients who had their colon removed and whose diverticulitis was histologically proven, and in the evaluation of the severity of the inflammation (26 vs. 9 percent; P = 0.02).	11052512
Inflammation, Tumor necrosis	Altered Intercellular Communication	At the same time, we measured plasma atrial natriuretic peptide levels and plasma renin activity, and, as a marker of inflammation, plasma levels of tumour necrosis factor.	11052927
Inflammation, Oculovestibuloauditory syndrome	Altered Intercellular Communication	This is the first case exhibiting that topical cyclosporin A is an effective treatment for severe anterior segment inflammation associated with Cogan syndrome.	11054005
Inflammatory abnormality of the eye	Altered Intercellular Communication	Preoperative and postoperative visual acuity, ocular inflammation, anti-inflammatory medication use, and intraocular pressure.	11054326
Inflammation, Gastrointestinal irritation	Altered Intercellular Communication	It is caused by gastrointestinal irritation and inflammation.	11054515
Refractory anemias, Inflammation	Altered Intercellular Communication	The mRNA levels of IL-4 and IL-10 were very low compared to those of IL-12 in seven of the 30 patients with RA; all of these patients were in stage 4, and serum levels of CRP, ESR and blood platelet count which are considered as indices of the severity of inflammation, were significantly elevated in these seven patients compared to the other 23 RA patients.	11055825
Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Purpura	Altered Intercellular Communication	Drug-induced leukocytoclastic vasculitis is clinically characterised by inflammation of small vessels and skin alterations, typically palpable purpura.	11057395
Inflammation, Neoplasms	Altered Intercellular Communication	The case is presented because MRI did not allow a specific diagnosis of osteoid osteoma, and suggested the tumor was larger than in reality it was, by also depicting the reactive inflammation around the tumor as if it were part of the tumor.	11057537
Pancreatitis	Altered Intercellular Communication	In severe cases operative endoscopy cured pancreatic inflammation in 12 cases.	11059236
Inflammation, respiratory	Altered Intercellular Communication	These results suggested that eosinophilic inflammation rather than hypo-osmolar effect of fog might contribute to respiratory deterioration by inhalation of naturally-occurring acid fog.	11059945
Inflammation, Urinary tract infection	Altered Intercellular Communication	We conducted a randomized, multicenter, double-blind study comparing imipenem to ceftazidime in patients with urinary tract infections caused by Gram-negative bacilli associated with signs and symptoms of systemic inflammation.	11061029
Inflammation, Carcinogenesis	Altered Intercellular Communication	A role for inflammation, and consequently of non-steroidal anti-inflammatory drugs, in ovarian carcinogenesis has been proposed, but epidemiological evidence is scanty.	11061614
Interstitial Cystitis, Cystitis	Altered Intercellular Communication	Although the exact etiology of interstitial cystitis remains elusive, bladder inflammation appears to be common in many patients.	11061878
Interstitial Cystitis, Inflammation	Altered Intercellular Communication	We determine if the severity of cystoscopic findings correlated with histological evidence of inflammation in patients with suspected interstitial cystitis.	11061878
Inflammation	Altered Intercellular Communication	Histological examination revealed no inflammation in 21 patients (30%), mild inflammation in 28 (41%), moderate inflammation in 11 (16%) and severe inflammation in 9 (13%).	11061878
Interstitial Cystitis, Inflammation	Altered Intercellular Communication	Severity of cystoscopic findings observed during hydrodistention with anesthesia does not appear to correlate with the degree of inflammation identified histologically in patients with suspected interstitial cystitis.	11061878
Inflammation	Altered Intercellular Communication	The lesion exhibited no features of inflammation or fat and was also negative for S-100 staining.	11063118
methionine, Inflammation	Altered Intercellular Communication	In both the study and the control groups, PI, MI, and MET were found to be increased due to inflammation.	11063389
Inflammation, Intervertebral Disk Displacement	Altered Intercellular Communication	Even when straight leg raising was < 47.5 degrees, three times more disc herniations lacked (n = 34) inflammatory cells than showed (n = 13) inflammation.	11064526
Inflammation	Altered Intercellular Communication	The posterior wall of the right atrium and the posterior basal wall of the left ventricle presented the greatest intensities of inflammation.	11064759
Inflammation, Hypersensitivity	Altered Intercellular Communication	However, as there was no significant correlation between the intensity of the lesions and the quantity of parasitic antigen, other mechanisms, such as auto-immunity or hypersensitivity, may stimulate the inflammation.	11064759
Inflammation, Pseudoaneurysm	Altered Intercellular Communication	Histopathological examination revealed the presence of a pseudoaneurysm but no inflammation.	11064870
Granulomatous inflammation	Altered Intercellular Communication	Histological examination showed a diffuse granulomatous inflammation with numerous histiocytes containing Michaelis-Gutmann bodies.	11064905
Airway structure, Asthma	Altered Intercellular Communication	Corticosteroids are considered to be one of the most effective medicine for asthma by suppressing airway inflammation.	11068988
Granulomatous inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	There were multifocally-distributed transmural vasculitis showing all stages of activity in medium and small-sized arteries and veins located in the submucosa, and proper muscle and subserosal layers of the colon, some of which revealed granulomatous inflammation.	11068998
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	These results suggest that oxidative stress might be implicated in promoting a state of low-grade systemic inflammation in elderly patients with type II diabetes.	11069205
Catheter infection, Inflammation	Altered Intercellular Communication	Despite local inflammation of the skin around the tunnel in nine patients (27%), no catheter infection (positive culture tip) was found in patients with subcutaneous tunnelling for the extended period of 4-5 days.	11069341
Airway structure, Asthma	Altered Intercellular Communication	NO is increased in exhaled air of asthmatic patients, and may be used as a marker of airway inflammation.	11069821
Inflammation, Diffuse panbronchiolitis, Bronchiolitis	Altered Intercellular Communication	Diffuse panbronchiolitis (DPB) is characterized by chronic neutrophil-mediated inflammation of the airway mediated by oxygen radical production.	11070461
Pain Distress Question, Sore to touch, Appendicitis, CTCAE, Inflammation	Altered Intercellular Communication	Negative explorations in patients with suspected appendicitis are related to systematic errors in the clinical diagnosis with too strong an emphasis on pain and tenderness, and too little attention paid to duration of symptoms and objective signs of inflammation.	11071167
Inflammation	Altered Intercellular Communication	Pets are a potential reservoir for putative microbial agents that could be a stimulus for chronic inflammation subject to the influence of immunogenetic factors.	11071582
Inflammation, Hepatitis, Chronic, Malignant Neoplasms	Altered Intercellular Communication	Repeated ultrasound-guided biopsies from the lesions as well as from the adjacent normal appearing liver tissue revealed no malignancy but showed inflammation and significant fibrotic tissue, consistent with chronic hepatitis C. 2 years after the first admission liver function tests were all within the normal range and remained so until today.	11072678
Inflammation, Leukopenia	Altered Intercellular Communication	These findings provide additional evidence for the existence of an unrecognized low-grade chronic inflammatory process in NI-CINA patients and coroborate our previously reported suggestion for the possible involvement of this inflammation in the pathogenesis of neutropenia in the affected subjects.	11073164
Inflammation	Altered Intercellular Communication	Increasing evidence suggests that tachykinins are involved in the control of pathophysiological states, such as inflammation.	11073811
Inflammation, Leukopenia	Altered Intercellular Communication	If this chronic inflammation is really the cause of the disorder or it simply represents the result of neutropenia remains to be elucidated.	11074551
Histiocytosis, Langerhans-Cell, Plasmacytoma, Inflammation, Specimen Source Codes - Abscess	Altered Intercellular Communication	Review of the diagnoses for the 79 aspiration specimens revealed 30 cases diagnosed as lymphoma/atypical lymphocytic infiltrate, cases diagnosed as inflammation or abscess, three cases diagnosed as plasmacytoma, three cases called suboptimal with scant inflammatory cells, and one case of Langerhans' cell histiocytosis.	11074624
Inflammation, Disease Steps Questionnaire	Altered Intercellular Communication	In summary, the high incidence of chronic inflammation of the long head of the biceps in shoulders with benign-appearing intraarticular portions viewed arthroscopically is significant, and long head of the biceps disease should also be considered in patients with painful rotator cuff disease and arthritic shoulder conditions.	11075320
Intraocular inflammation, "Fuchs heterochromic cyclitis	Altered Intercellular Communication	Fuchs' heterochromic uveitis is characterized by low-grade intraocular inflammation and a relatively benign clinical course.	11076346
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Under the impression of chronic inflammation and suspicion of cancer recurrence, the patient was transferred to the Tri-Service General Hospital.	11076434
Cytomegalovirus Infections, Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Host response to cytomegalovirus infection as a determinant of susceptibility to coronary artery disease: sex-based differences in inflammation and type of immune response.	11076822
Inflammation	Altered Intercellular Communication	In men, CMV appears to contribute to CAD risk, insofar as it predisposes to inflammation.	11076822
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The degree of inflammation and fibrosis was less in NBNC-HCC cases, and two cases (15.4%) had almost normal liver histology.	11078825
Acute inflammation, Herpetic whitlow	Altered Intercellular Communication	Herpetic keratouveitis may occur after argon laser iridotomy, and it should be considered when postoperative inflammation persists despite appropriate use of topical corticosteroids, particularly in patients with a history of herpetic eye disease.	11078848
Airway structure	Altered Intercellular Communication	We tested the hypothesis that response to prednisolone is related to the presence of eosinophilic airway inflammation.	11081531
Airway structure, ARCN1 gene	Altered Intercellular Communication	Our findings suggest that eosinophilic airway inflammation contributes to airflow obstruction and symptoms in some patients with COPD and that the short-term effects of prednisolone are due to modification of this feature of the inflammatory response.	11081531
Inflammation	Altered Intercellular Communication	We sought to determine the prognostic value of serum albumin for 4-year mortality among high-functioning persons who did or did not have evidence of inflammation as indicated by high interleukin-6 (IL-6) levels.	11083315
Pancreatitis, Acute	Altered Intercellular Communication	Besides the classic theories and their own approach to the management of an acute pancreatic inflammation episode are discussed.	11086512
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Clinical and histopathological investigations demonstrated granulomatous inflammation with necrosis containing acid-fast rods in the tissue specimens.	11089212
Inflammation	Altered Intercellular Communication	The degree of mastoid cell pneumatization is considered an indicator of chronic inflammation of the middle ear.	11089993
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	Atherosclerotic lesions are characterized by an immune mediated chronic inflammation.	11090835
Ancriviroc, Fibrosis Assessment, Inflammation, Necrosis	Altered Intercellular Communication	There was a correlation between the ratio of CH-C and serum alanine aminotransferase, category I (periportal inflammation and necrosis), and IV (fibrosis) of the HAI scoring system.	11092253
Infertility, Kidney Failure	Altered Intercellular Communication	We report a case of a pregnant woman with luteal insufficiency and infertility associated with a variant luteinizing hormone (LH) beta-subunit and normal follicle-stimulating hormone (FSH) concentration.	11092704
Degenerative polyarthritis, Rheumatoid Arthritis	Altered Intercellular Communication	Neurotransmitter modulation of interleukin 6 (IL-6) and IL-8 secretion of synovial fibroblasts in patients with rheumatoid arthritis compared to osteoarthritis.	11093434
Refractory anemias	Altered Intercellular Communication	CGRP was the most potent stimulatory neurotransmitter in RA fibroblasts whereas the sympathetic adenosine, NE, beta-endorphin, and MENK were inhibitory.	11093434
Arthritis	Altered Intercellular Communication	The sensory nervous system with the 2 neurotransmitters substance P (SP) and calcitonin gene related peptide (CGRP) is proinflammatory in experimental models of arthritis.	11093434
Refractory anemias, Rheumatoid Arthritis, Degenerative polyarthritis	Altered Intercellular Communication	We studied the influence of these neurotransmitters on secretion of interleukin 6 (IL-6) and IL-8 in primary cultures of synovial fibroblasts of patients with rheumatoid arthritis (RA) compared to osteoarthritis (OA).	11093434
Degenerative polyarthritis	Altered Intercellular Communication	In OA fibroblasts, the sympathetic neurotransmitters were stimulatory at higher concentrations.	11093434
Myositis	Altered Intercellular Communication	After the exercise period there was no sign of increased muscle inflammation.	11093595
Postcoital bleeding, Inflammation	Altered Intercellular Communication	A 33-year-old nulligravida presented with postcoital bleeding and an extensive ulcerated lesion of the cervix that showed nonspecific inflammation on biopsy.	11094223
Inflammation, Granuloma	Altered Intercellular Communication	Complications included focal inflammation of the host conjunctiva adjacent to the graft (six eyes), scar formation (five eyes), and suture-induced granuloma (one eye).	11095053
Inflammation, Astigmatism	Altered Intercellular Communication	The technique reduces postoperative inflammation, suture-related problems including astigmatism, and allows more rapid rehabilitation.	11095122
Inflammation, Cardia of stomach	Altered Intercellular Communication	Helicobacter pylori eradication dramatically improves inflammation in the gastric cardia.	11095325
Helicobacter pylori, Communicable Diseases, Gastroesophageal reflux disease, Carditis, Cardia of stomach	Altered Intercellular Communication	Inflammation of the gastric cardia, i.e., "carditis," has been associated with Helicobacter pylori (H. pylori) infection; however, some investigators believe carditis to be a histological marker for gastroesophageal reflux disease.	11095325
Inflammation, Cardia of stomach	Altered Intercellular Communication	At pretreatment and, on average, 2 yr after eradication of H. pylori, the degree of inflammation in the gastric cardia and H. pylori status were blindly assessed by a single pathologist.	11095325
Inflammation, Carditis	Altered Intercellular Communication	After eradication therapy, there was a significant decrease (p < 0.0001) in the carditis scores (activity and inflammation scores) in group I, whereas the scores remained unchanged in group II patients.	11095325
Communicable Diseases, Inflammation, Cardia of stomach	Altered Intercellular Communication	There is a dramatic improvement in the degree of inflammation and activity scores in the gastric cardia of patients with successful H. pylori eradication compared to those with persistent infection.	11095325
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	By using a stent to treat coronary artery disease, a foreign body is directly juxtaposed with an area of inflammation.	11097126
Inflammation, Postoperative Complications, Vitreous incarceration	Altered Intercellular Communication	These induce two major postoperative complications: chronic inflammation and influence on the adjacent vitreous such as vitreous incarceration.	11097591
Vitreous Hemorrhage, Vitreous inflammatory cells, NCI CTEP SDC Retinoblastoma Sub-Category Terminology	Altered Intercellular Communication	Retinoblastoma may present with atypical features such as vitreous hemorrhage or signs of vitreous inflammation, particularly in older children.	11097606
Communicable Diseases, Helicobacter pylori, Inflammation	Altered Intercellular Communication	Infection with Helicobacter pylori in childhood may be the initiation of a lifelong coexistence between microorganisms and epithelial cells resulting in chronic inflammation.	11099055
Inflammation, Primary malignant neoplasm, Bile duct dysplasia	Altered Intercellular Communication	Since bile duct dysplasia induced by chronic inflammation may be a precursor of cancer, indication for choledochoduodenostomy should be specific and limited, and careful long-term follow-up is mandatory.	11100322
Lymphohistiocytosis, Hemophagocytic, Angioendotheliomatosis	Altered Intercellular Communication	Angiotropic B-cell lymphoma with hemophagocytic syndrome associated with syndrome of inappropriate secretion of antidiuretic hormone.	11100751
Pain Distress Question, Inflammation	Altered Intercellular Communication	Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used and effective treatments for pain and inflammation.	11102559
Inflammation	Altered Intercellular Communication	COX-1 generates prostaglandins with physiological functions, COX-2 is induced by inflammation and its physiologic functions are unclear at present.	11102559
Inflammation, Lymphocytic infiltration, Myositis, CTCAE 5.0, myonecrosis	Altered Intercellular Communication	Histologic examination of the biopsy specimen showed muscle cell necrosis and severe inflammation, with lymphocytic infiltration leading to the diagnosis of focal myositis.	11103443
Inflammation, Hemorrhage, Pulmonary Edema, CTCAE	Altered Intercellular Communication	Postmortem study revealed extensive inflammation in the meninges and central nervous system and marked pulmonary edema with focal hemorrhage.	11106077
Airway structure, Tumor necrosis, Asthma	Altered Intercellular Communication	Tumour necrosis factor (TNF)alpha is a cytokine endowed with potent inflammatory properties that may contribute to airway inflammation in asthma.	11106199
Airway structure, ARCN1 gene	Altered Intercellular Communication	However, the role of the common cold virus (human rhinovirus) in the production of symptoms and lower airway inflammation at COPD exacerbation is unknown.	11106212
Acute myocardial infarction, Inflammation	Altered Intercellular Communication	Here we studied patients for plasma IL-10 after acute myocardial infarction, a very stressful event without significant signs of systemic inflammation.	11108135
Communicable Diseases, Inflammation, Coronary Artery Disease, Endothelial dysfunction	Altered Intercellular Communication	Recent research has demonstrated that successful simultaneous treatment of multiple risk factors including cholesterol, triglycerides, homocysteine, lipoprotein (a) [Lp(a)], fibrinogen, antioxidants, endothelial dysfunction, inflammation, infection, and dietary factors can lead to the regression of coronary artery disease and the recovery of viable myocardium.	11108325
ACSM3 gene, Arachnoiditis, Cerebral Ischemia, Vasospasm	Altered Intercellular Communication	The demonstration that endothelin-1 is produced by activated CSF mononuclear leukocytes suggests that subarachnoid inflammation may represent a therapeutic target to prevent vasospasm and delayed cerebral ischemia after SAH.	11108758
Communicable Diseases, Swelling, Inflammation, Necrosis	Altered Intercellular Communication	Nonblinded assessments were made regarding wound leakage, inflammation, infection, necrosis, swelling, dehiscence and cosmesis.	11109037
Inflammation	Altered Intercellular Communication	There were trends toward increased rates of in-hospital sternal (P=0.09) and leg (P=0.17) incision inflammation when the wounds were closed with skin clips.	11109037
Eosinophilic disorder, Inflammation	Altered Intercellular Communication	In the course of treatment the signs of inflammation, including the eosinophilia, regressed or became normal.	11109414
Inflammation, Acid reflux, Neoplasms	Altered Intercellular Communication	Each patient met the criteria for 'primary globus pharyngeus' (Bradley 1987) as determined by endoscopy and none of the patients showed any signs of inflammation, tumors, or gastroesophageal reflux.	11109825
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In the interstitium, both in the cortex and the medulla, there was focal inflammation and fibrosis.	11110045
Communicable Diseases, Inflammation	Altered Intercellular Communication	The possible mechanisms include chronic inflammation in the coronary artery due to persistent C. pneumoniae infection.	11110424
Inflammation, Leukocytosis	Altered Intercellular Communication	The inflammation meter: novel technology to detect the presence of infection/inflammation in patients without leukocytosis but with increased leukocyte adhesiveness/aggregation.	11111116
Inflammation, Leukocytosis, Leukostasis, Leukopenia	Altered Intercellular Communication	Our present finding that 63% out of the group with documented infection/inflammation and no leukocytosis had a significantly increased LAAT suggest that the lack of leukocytosis is in part a pseudoleukopenia, or is associated with some degree of uncompensated tissue leukostasis.	11111116
Inflammation	Altered Intercellular Communication	The lack of a leukocytic response in a patient with nonviral infection/inflammation is by no means a sign of a less inflammatory response.	11111116
Inflammation	Altered Intercellular Communication	The increased state of leukocyte adhesiveness/aggregation might help to disclose the presence of inflammation in these individuals.	11111116
Inflammation	Altered Intercellular Communication	However, the orosomucoid concentrations obtain-ed provide no evidence of significant inflammation.	11111244
Inflammation	Altered Intercellular Communication	The high affinity of haptoglobin (Hp) for hemoglobin (Hb) results in the formation of soluble Hp-Hb complexes, reducing the value of Hp as a marker of the acute phase of inflammation.	11111244
Inflammation, Diffuse panbronchiolitis, Bronchiectasis, Bronchiolitis, Sinusitis, Lung diseases	Altered Intercellular Communication	Diffuse panbronchiolitis (DPB) is a pulmonary disease of unknown origin with inflammation in the respiratory bronchioles, bronchiectasis, and recurrent sinusitis.	11112141
Inflammation, SMALL PATELLA SYNDROME, Pelvic Pain, Disease, Elastosis perforans serpiginosa	Altered Intercellular Communication	Chronic prostatitis/chronic pelvic pain syndrome (CPPS) is a disorder characterized by pelvic pain and varying degrees of inflammation exhibited in expressed prostatic secretions (EPS).	11113752
Inflammation, Bacterial prostatitis, Benign prostatic hypertrophy, Elastosis perforans serpiginosa	Altered Intercellular Communication	To provide objective parameters of inflammation, we measured the cytokines interleukin 8 (IL-8) and epithelial neutrophil activating peptide 78 (ENA-78) in EPS of healthy men, men with benign prostatic hyperplasia (BPH), men with bacterial prostatitis (BP), and men with chronic prostatitis/CPPS.	11113752
Inflammation, Necrosis	Altered Intercellular Communication	These data strongly suggest that CGCGs associated with teeth with necrotic pulps are not directly related to periapical inflammation and may be misdiagnosed as endodontic lesions.	11113820
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	These results suggest that IL-8 may, through CXCR1, have a role beyond neutrophil recruitment in mediating the immune response in UC and that this is not merely a consequence of the acute inflammation seen in UC.	11113872
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Chronic inflammation and astrocytosis are characteristic histopathological features of Alzheimer's Disease (AD).	11114266
Inflammation, Anemia, Protein-Energy Malnutrition	Altered Intercellular Communication	Prevalence of anemia in elderly subjects living at home: role of micronutrient deficiency and inflammation.	11114677
Inflammation, Pericarditis, CTCAE	Altered Intercellular Communication	Pericarditis may be caused by direct invasion or immune-complex-mediated (reactive) inflammation.	11115043
Peripheral facial palsy, Granulomatous Cheilitis	Altered Intercellular Communication	Granulomatous cheilitis (GC) is a chronic granulomatous inflammation of the lips of unknown etiology, which may be associated with peripheral facial nerve paralysis and/or lingua plicata (Melkersson-Rosenthal syndrome [MRS]).	11115161
Airway structure, Bronchitis	Altered Intercellular Communication	Airway inflammation and etiology of acute exacerbations of chronic bronchitis.	11115440
Airway structure	Altered Intercellular Communication	If bacterial pathogens cause these AECB, they should be associated with greater neutrophilic airway inflammation than pathogen-negative exacerbations.	11115440
Airway structure	Altered Intercellular Communication	Increased airway inflammation associated with isolation of H influenzae and M catarrhalis supports an etiologic role of these pathogens in AECB.	11115440
Inflammation, Pathologic Intimal Thickening, Atherosclerosis	Altered Intercellular Communication	These data suggest that genetic factors that predispose to reduced matrix remodeling (stromelysin 6A allele) and to increased inflammation (IL-6 G allele) combine to increase susceptibility for intima-media thickening in the carotid bifurcation, a predilection site for atherosclerosis.	11116068
Lewy Bodies, Presenile dementia, dendritic lamellar body, Delusions, CTCAE, Abnormal degeneration	Altered Intercellular Communication	The relation between disturbances of cholinergic neurotransmission and delusions (DELs) has not been investigated in degenerative dementias such as dementia with Lewy bodies (DLB).	11117543
Inflammation, Cardiovascular Diseases, Failure (biologic function)	Altered Intercellular Communication	One explanation for discrepant results between epidemiologic studies and randomized trials of beta-carotene and cardiovascular disease may be a failure to consider inflammation as a confounder.	11117616
Osteitis	Altered Intercellular Communication	Magnetic resonance imaging of the left hip joint showed marked regression of bone inflammation 4 months later and normalization after 8 months.	11117643
Uveitis	Altered Intercellular Communication	Despite important advances in the therapeutic management of acute intraocular inflammation, the long-term impact of these new strategies on visual outcome of BD and their efficacy in different ethnic groups is unknown.	11120575
Airway structure, ARCN1 gene, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	It has been implicated in the pathogenesis of asthma and virally mediated airway inflammation and may play a role in exacerbations of chronic obstructive pulmonary disease (COPD).	11120901
Airway structure, ARCN1 gene, Exacerbation	Altered Intercellular Communication	Relationship between airway inflammation and the frequency of exacerbations in patients with smoking related COPD.	11120902
ARCN1 gene, Chronic Obstructive Airway Disease, Bronchitis	Altered Intercellular Communication	Patients with more frequent exacerbations of chronic obstructive pulmonary disease (COPD) may have increased bronchial inflammation.	11120902
Airway structure, ARCN1 gene, Exacerbation	Altered Intercellular Communication	Airway inflammation (spontaneous sputum sol phase myeloperoxidase (MPO), elastase, leukotriene (LT)B(4), interleukin (IL)-8, secretory leukoprotenase inhibitor (SLPI), protein leakage) and serum levels of C reactive protein (CRP) were compared in 40 patients with stable, smoking related COPD, divided into those with frequent (> or =3/year) or infrequent (< or =2/year) exacerbations according to the number of primary care consultations during the preceding year.	11120902
ARCN1 gene, Bronchitis	Altered Intercellular Communication	There are several clinical features that directly influence bronchial inflammation in COPD.	11120902
Inflammation, ACTH Deficiency, Isolated	Altered Intercellular Communication	Quantitative analysis of CD36 expression on DCs as a marker of inflammation, as well as the percentage of inflammatory dendritic epidermal cells in the CD1a+ epidermal DC pool, indicated a comparable disease activity in IAD and EAD.	11122020
Vitreous inflammatory cells, Edema	Altered Intercellular Communication	No vitreous inflammation or macular edema was found.	11124321
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide--is it really a good marker of airway inflammation in bronchial asthma?	11124647
Airway structure	Altered Intercellular Communication	However, it is not fully understood whether it equally reflects the degree of airway inflammation in patients receiving inhaled corticosteroids, but whose symptoms are not necessarily well controlled.	11124647
Airway structure, Asthma	Altered Intercellular Communication	To examine whether the exhaled [NO] really reflects airway inflammation in patients with bronchial asthma, regardless of treatment with inhaled steroids.	11124647
Airway structure, Asthma	Altered Intercellular Communication	We examined in each asthmatic group whether the exhaled [NO] correlated with parameters reflecting airway inflammation.	11124647
Airway structure	Altered Intercellular Communication	Exhaled [NO] was significantly correlated with symptom score, clinical severity, circulating eosinophil count, and the percentage of eosinophils in induced sputum in the steroid-naive asthmatics, but not in the steroid-treated asthmatics, although airway inflammation in this group was not well controlled, as evidenced by clinical symptoms and the higher percentage of eosinophils in induced sputum.	11124647
Airway structure, Asthma	Altered Intercellular Communication	Although exhaled [NO] is a useful marker of airway inflammation for differential diagnosis and evaluation of severity in steroid-naive patients with bronchial asthma, it may not be as useful in steroid-treated patients.	11124647
Scab, Structure of meibomian gland, Hyperemia	Altered Intercellular Communication	Blepharokeratitis is a chronic external ocular and adnexal inflammatory condition marked by erythematous and edematous lid margins, lid margin crusting and scaling, meibomian gland inflammation and inspissation, and conjunctival hyperemia.	11124676
Inflammation	Altered Intercellular Communication	The inflammation sometimes leads to corneal thinning, scarring, and vascularization.	11124676
Scab, Structure of meibomian gland, Hyperemia	Altered Intercellular Communication	Blepharokeratitis is a chronic external ocular and adnexal inflammatory condition marked by erythematous and edematous lid margins, lid margin crusting and scaling, meibomian gland inflammation and inspissation, and conjunctival hyperemia.	11124676
Hepatitis	Altered Intercellular Communication	Furthermore, the relative rarity of circulating CD8(+) effector T cells in chronically infected patients may explain the chronic insidious nature of the liver inflammation and also why they fail to eliminate the virus.	11124845
Granulomatous inflammation, Crohn Disease	Altered Intercellular Communication	Review of the pathological sections from the resected hip, however, resulted in detection of granulomatous inflammation with multinucleated giant cells - the histological 'footprint' of Crohn's disease in the gastrointestinal tract.	11125186
Sclerosis, Inflammation, Erythema, Hypopigmentation disorder	Altered Intercellular Communication	The skin lesions had a normal texture and showed no signs of inflammation, lilac ring, erythema, induration, sclerosis or depigmentation.	11125323
Refractory anemias, Inflammation, Tissue damage	Altered Intercellular Communication	This finding suggested that RA patients had increased oxidant stress that might play a role in the tissue damage and inflammation process of this disease.	11127335
Inflammation, Restenosis	Altered Intercellular Communication	This finding supports a role of inflammation in the development of restenosis after stent placement.	11127457
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Idiopathic granulomatous inflammation of the pituitary gland occurs rarely, and is usually identified as an incidental finding at autopsy.	11128623
Inflammation, Perforation (observation)	Altered Intercellular Communication	To study the hypothesis that perforation of the rotator cuff increases the degree of inflammation in the synovium of the glenohumeral joint in rotator cuff diseases.	11128681
Inflammation	Altered Intercellular Communication	The cystic duct may be hidden in some patients having laparoscopic cholecystectomy, especially in the presence of inflammation.	11129816
Ovarian Hyperstimulation Syndrome, Blood Coagulation Disorders	Altered Intercellular Communication	In vitro fertilization with hormonal stimulation may cause serious complications in patients with unknown coagulation disorders or with an ovarian hyperstimulation syndrome.	11130121
Inflammation, Hepatobiliary Disorder, Fibrosis Assessment, Deposition	Altered Intercellular Communication	Biopsies with concurrent liver disease (n=28) presented with significantly more severe inflammation and fibrosis, and more PiZ deposits than the cases without concurrent liver disease.	11131449
Communicable Diseases, Inflammation, Headache	Altered Intercellular Communication	A prodrome, such as a browache, headache, or external eye inflammation or infection, was documented in previous physician visits in 7 (35%) of 20 patients.	11131749
Inflammation	Altered Intercellular Communication	Colonoscopy showed moderate signs of inflammation of the rectum and aphthoid ulcerations in the terminal ileum.	11132537
Cataract, Demographics Domain, Diabetes Mellitus	Altered Intercellular Communication	To investigate change in the area of anterior capsular opening (ACO) after cataract surgery and its relation to the degree of postoperative anterior inflammation in patients with diabetes mellitus (DM).	11133706
Conjunctivitis, Keratoconjunctivitis Sicca	Altered Intercellular Communication	This study confirms that cyclosporin A may be efficient in reducing conjunctival inflammation in moderate to severe KCS and is consistent with clinical results in this indication.	11133852
Cataract	Altered Intercellular Communication	To report 10 cases of delayed-onset acute intraocular inflammation following cataract extraction and posterior chamber implantation of the MemoryLens(R) intraocular lens (IOL).	11134878
Cataract, Acute inflammation	Altered Intercellular Communication	This retrospective study evaluated 10 cases of postoperative inflammation that occurred after cataract extraction with placement of the posterior chamber MemoryLens IOL.	11134878
Acute inflammation	Altered Intercellular Communication	Protocols of the Intermountain Ocular Research Center used to analyze outbreaks of unexplained postoperative inflammation as well as medical records were reviewed.	11134878
Inflammation	Altered Intercellular Communication	All 10 patients presented with increased anterior segment inflammation a mean of 7.8 days (range 1 to 21 days) after surgery.	11134878
Inflammation	Altered Intercellular Communication	Our case report further illustrates the importance of ultrafiltration failure as an early and main symptom of peritoneal inflammation.	11136199
Cholangitis, Sclerosing, Inflammation, Granular cell tumor, Neoplasms	Altered Intercellular Communication	Of 132 consecutive patients undergoing resection for a suspicious lesion at the hepatic hilum, 20 (15 per cent) had a histopathologically proven benign tumour, diagnosed as chronic fibrosing or erosive inflammation, sclerosing cholangitis, or a granular cell tumour.	11136309
Inflammation, Synovial Hypertrophy, Bone necrosis, Hemosiderosis	Altered Intercellular Communication	A histological examination revealed bone necrosis, nonspecific inflammation, haemosiderosis and synovial hypertrophy.	11136395
Inflammation, Hemorrhage	Altered Intercellular Communication	The recurrent bleeding into the hip joint induced pronounced inflammation with synovial proliferation and acute destruction of bony tissue.	11136395
Rheumatoid Arthritis	Altered Intercellular Communication	Cellular immune response to human cartilage glycoprotein-39 (HC gp-39)-derived peptides in rheumatoid arthritis and other inflammatory conditions.	11136874
Refractory anemias	Altered Intercellular Communication	In RA patients as well as in patients with other inflammatory conditions, HC gp-39-derived peptides may be targets of the T-cell-mediated immune response.	11136874
Inflammation, Degenerative polyarthritis, Rheumatoid Arthritis, destruction joint, Arthritis	Altered Intercellular Communication	To study the levels of matrix metalloproteinase-3 (MMP-3) in the knee synovial fluid (SF) of inflammatory arthropathies (rheumatoid arthritis whether erosive or not, reactive arthritis, acute crystal arthritis) and degenerative arthropathies [chronic crystal disease, osteoarthritis and (control) meniscus pathology] and to correlate them with the degree of joint destruction, local inflammatory and immune parameters and systemic markers of inflammation.	11136879
Inflammation, senile	Altered Intercellular Communication	These results show that IL-4, IL-10, and IL-13 differentially regulate microglial responses to A beta and may play a role in the inflammation pathology observed surrounding senile plaques.	11137576
Fibrinoid necrotizing inflammation	Altered Intercellular Communication	Estrogen up-regulates IL-1 beta-induced IL-6 production in cultured fibroblast-like synoviocytes, possibly contributing to the enhancement of rheumatoid inflammation in synovial tissues.	11138340
Helicobacter pylori, Gastritis	Altered Intercellular Communication	Nucleic acid amplification was performed for five loci in the cag pathogenicity island (PAI) of Helicobacter pylori (comprising cagA, the cagA promoter region, cagE, cagT, and the left end of cagII [LEC]), and gastric inflammation in patients was evaluated.	11139216
Inflammation	Altered Intercellular Communication	One patient complained of chronic inflammation of the cervix and another experienced rejection of the posterior mesh 6 months after the operation.	11139710
Communicable Diseases, Inflammation, Fever, CTCAE	Altered Intercellular Communication	In 1994, a 80-year-old male presented with a pacemaker pocket infection, cutaneous inflammation but no fever 2 months after insertion of a pacemaker.	11140083
Inflammation	Altered Intercellular Communication	One month after re-insertion, the patient again presented a cutaneous inflammation, and S. schleiferi was isolated from the pus as well as the generator and the leads on their removal.	11140083
Inflammation	Altered Intercellular Communication	Whereas the mechanism of this interaction is not known, it is plausible that the metabolism of carcinogenic intermediates or the response to chronic inflammation associated with smoking may be modulated by the GSTT1 genotype and may modify CaP risk.	11142418
Inflammation, Calculi, Perforation (observation)	Altered Intercellular Communication	However, acute inflammation and perforation secondary to a calculus is a rare clinical presentation.	11143326
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histology was interpreted according to a defined numerical score of inflammation and fibrosis by a single pathologist.	11143539
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Scores of fibrosis and inflammation were correlated with biochemical and virological parameters.	11143539
Fibrosis Assessment, Hepatitis C, Hepatitis	Altered Intercellular Communication	If prior to treatment of chronic hepatitis C liver biopsy is omitted and the decision for treatment depends solely on the measurement of surrogate markers, considerable misjudgement of the actual status of liver inflammation or fibrosis may result.	11143539
Pancreatitis, Alcoholic Intoxication, Chronic, Biliary lithiasis	Altered Intercellular Communication	The main causes of pancreatic inflammation worldwide are biliary lithiasis and alcoholism.	11144021
Inflammatory disease of mucous membrane	Altered Intercellular Communication	It is likely that this is due to ongoing subclinical mucosal inflammation.	11145287
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	The hepatic inflammation activity and the severity of fibrosis were evaluated using Desmet classification.	11145295
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Both insulin-like growth factor-I and insulin-like growth factor binding protein-3 levels did not correlate with inflammation activity, fibrosis or transaminase levels.	11145295
Inflammation, Osteopenia	Altered Intercellular Communication	The severity of inflammation, as rated according to Gingival Index, did not correlate with the category of bone loss (p > 0.05).	11145357
Retinitis, Necrosis of retina, Choroiditis	Altered Intercellular Communication	Retinitis (10/18 eyes), retinal necrosis (4/18 eyes), disruption of the retinal pigment epithelium (12/18 eyes), and choroidal inflammation and congestion (15/18 eyes) were characteristic findings.	11146726
Inflammation, Granuloma	Altered Intercellular Communication	Frequent recurrence of chronic inflammation and epitheloid cell granuloma formation may have resulted from an aberration of the ectopic remaining pancreatic tissue in the spleen.	11148465
Inflammation, Necrosis	Altered Intercellular Communication	Histologic features included mineralization (20 of 33), foci of necrosis (4 of 33), chronic inflammation (4 of 33), ganglion cell differentiation (1 of 33), and lipomatous differentiation (1 of 33).	11148570
Conjunctivitis	Altered Intercellular Communication	A decrease in conjunctival inflammation during the course of IVIg was documented by monthly examination in every patient and paralleled the decrease in titer of anti-beta 4 antibodies.	11148601
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	Discriminating allergy from nonspecific inflammation has become of striking importance for diagnosis and treatment.	11148813
Communicable Diseases, Inflammation, Thromboembolism	Altered Intercellular Communication	The relationship between systemic infection or inflammation and an increased risk of thrombotic diseases has recently raised renewed interest.	11150578
Inflammation	Altered Intercellular Communication	The results indicate that in addition to the extent of detachment, and presence of preoperative inflammation or low grade PVR, iatrogenic problems also are important factors in the pathogenesis of severe PVR after surgery for RD.	11151263
Acute Coronary Syndrome, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Recent clinical data supported the role of endothelial dysfunction in patients with acute coronary syndrome and demonstrated a relation with elevated C-reactive protein levels, an unspecific marker of inflammation.	11151799
Inflammation, Abnormally opaque structure (morphologic abnormality), Edema	Altered Intercellular Communication	Ground-glass opacity in PDAs pathologically corresponded to inflammation and edema in the alveolar space.	11153686
Exanthema, Inflammatory abnormality of the eye, Prolonged, Impaired tactile sensation, Neuralgia	Altered Intercellular Communication	Patient age, acute neuralgia score, manifestation and extent of acute skin rash, signs of ocular inflammation, and nontrigeminal cranial nerve involvement were all associated with prolonged pain and tactile sensory loss.	11153792
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	No correlation was observed between HPC or hepatic UROD activity values and HCV-RNA concentrations, Knodell's score, hepatic fibrosis, periportal necrosis, periportal inflammation or hepatic iron content in HCV-infected patients.	11155151
Pseudotumor, Autoimmune reaction	Altered Intercellular Communication	Inflammatory pseudotumor is considered to be a benign inflammatory condition simulating a neoplasma and the possibility of an autoimmune reaction is suggested on the basis of etiology.	11155596
Graves Disease, Orbital Pseudotumor	Altered Intercellular Communication	Somatostatin-receptor (SSTR) scintigraphy using the single photon emission computed tomography (SPECT) technique allows the assessment of orbital inflammation in patients with Graves' disease.	11155823
Craniocerebral Trauma, Brain Injuries, Late Post-Traumatic Seizures, Brain Hypoxia	Altered Intercellular Communication	Post-traumatic seizures (PTS) can be a serious complication of head injury, because they can cause secondary brain damage through increased metabolic requirements, raised intracranial pressure, cerebral hypoxia, and/or excessive release of neurotransmitters.	11156302
Communicable Diseases, Helicobacter pylori, Inflammation	Altered Intercellular Communication	Gastric mucosa responds with inflammation to Helicobacter pylori (H. pylori) infection.	11156324
APP gene, Inflammation, Aortic Aneurysm, Abdominal, Atherosclerosis	Altered Intercellular Communication	The pathogenesis of abdominal aortic aneurysms (AAA) is a complex process in which atherosclerosis and inflammation play a leading role.	11156350
Inflammation, Dysplasia	Altered Intercellular Communication	Inflammation and dysplasia may affect the ileal pouch after restorative proctocolectomy and ileal pouch-anal anastomosis.	11156461
Inflammation, Dysplasia	Altered Intercellular Communication	The mucosal biopsy specimens were studied to investigate the degree of acute and chronic inflammation and the occurrence of dysplasia.	11156461
Inflammation, Dysplasia, "Crohns disease of large bowel", Ulcerative Colitis	Altered Intercellular Communication	After a median follow-up of 85 (range, 7-198) months, the inflammation histologic score evaluated was 3.8 (95 percent confidence interval, 2.4-5.1) and 3.5 (95 percent confidence interval, 2.6-4.3), respectively, in patients with Crohn's colitis and ulcerative colitis (mean and 95 percent confidence interval; P = 0.74, not significant), and no patient developed mucosal dysplasia.	11156461
Inflammation, "Crohns disease of large bowel", Ulcer	Altered Intercellular Communication	No difference in the inflammation histologic score was observed in ileal pouches after restorative proctocolectomy for ulcerative and Crohn's colitis.	11156461
Thrombus, Inflammation, Malignant Neoplasms, Vascular Diseases	Altered Intercellular Communication	After exclusion of known causes of FVIII elevation, such as the acute thrombotic event itself; inflammation; malignancy; liver, renal, or vascular disease; surgery; or pregnancy, we included 17 patients with unexplained, reproducibly high FVIII levels.	11156867
Airway structure	Altered Intercellular Communication	Interleukin 12 p40 production by barrier epithelial cells during airway inflammation.	11157054
Inflammation	Altered Intercellular Communication	Human airway epithelial cells appear specially programmed for expression of immune response genes implicated in immunity and inflammation.	11157054
Inflammation, Inflammatory disorder	Altered Intercellular Communication	The results placed epithelial cell overgeneration of IL-12 p40 as a key intermediate for virus-inducible inflammation and a candidate for epithelial immune response genes that are abnormally programmed in inflammatory disease.	11157054
Airway structure	Altered Intercellular Communication	Taken together, these results suggest a novel role for epithelial-derived IL-12 p40 in modifying the level of airway inflammation during mucosal defense and disease.	11157054
Communicable Diseases, Inflammation	Altered Intercellular Communication	Thus, infection and inflammation often precede ischemic neurological events.	11157171
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	There is growing evidence that the development of the atherosclerotic plaque is associated with inflammation.	11157411
Inflammation	Altered Intercellular Communication	These data suggest that increased exercise is associated with reduced inflammation.	11157411
Inflammation, Staphylococcus epidermidis, Discitis	Altered Intercellular Communication	Diskitis, an inflammation of the intervertebral disk, is generally attributable to Staphylococcus aureus and rarely Staphylococcus epidermidis, Kingella kingae, Enterobacteriaciae, and Streptococcus pneumoniae.	11158500
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	Topical ketorolac tromethamine 0.5% ophthalmic solution in ocular inflammation after cataract surgery.	11158809
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	To compare the efficacy and safety of ketorolac 0.5% ophthalmic solution with its vehicle in the treatment of ocular inflammation after cataract surgery and intraocular lens implantation.	11158809
Acute inflammation	Altered Intercellular Communication	Only patients with moderate or greater postoperative inflammation the day after surgery were enrolled.	11158809
Pain Distress Question, Photophobia, Inflammatory abnormality of the eye, CONJUNCTIVAL ERYTHEMA	Altered Intercellular Communication	Ketorolac was significantly more effective than vehicle in reducing the manifestations of postoperative ocular inflammation, including: anterior chamber cells (P: = 0.002) and flare (P: = 0.009), conjunctival erythema (P: = 0.010), ciliary flush (P: = 0.022), photophobia (P: = 0.027), and pain (P: = 0.043).	11158809
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	Ketorolac tromethamine 0.5% ophthalmic solution was significantly more effective than vehicle in the treatment of moderate or greater ocular inflammation following routine cataract surgery, while being as safe as vehicle.	11158809
Airway structure, Asthma, Residual volume	Altered Intercellular Communication	These events may be important in airway inflammation after minor group RV infection in asthma.	11159023
Inflammation, Data types - Address	Altered Intercellular Communication	Thus, FPRL1 may mediate inflammation seen in AD and is a potential target for developing therapeutic agents.	11160457
Inflammation, Neoplasms	Altered Intercellular Communication	He became increasingly confused and repeated CSF examination showed inflammation and a few suspicious cells but no definitive evidence of neoplasia.	11160482
Sepsis, Communicable Diseases, Inflammation, Traumatic injury	Altered Intercellular Communication	Surgery, trauma and inflammation reduce HLA-DR expression on monocytes, which is associated with an increased susceptibility to infection and sepsis.	11161542
Inflammation, "Alzheimers Disease", Nerve Degeneration	Altered Intercellular Communication	Inflammation plays a pivotal role in amyloid plaque progression thereby contributing to Alzheimer's disease-related neurodegeneration.	11162920
herpesvirus 3, human, Inflammatory abnormality of the eye	Altered Intercellular Communication	Six varicella-zoster virus DNA-positive patients had no signs of ocular inflammation.	11162975
Retinal Detachment, Inflammation, Hemorrhage, Exudate	Altered Intercellular Communication	There was no associated inflammation, exudate, hemorrhage, or serous retinal detachment.	11162995
Tuberculoma, Inflammation, Acquired Immunodeficiency Syndrome	Altered Intercellular Communication	Choroidal tuberculoma can present with little associated inflammation or retinal change in a patient with AIDS.	11162995
Uveitis	Altered Intercellular Communication	Persistent, low-grade smoldering corneal and intraocular inflammation required topical corticosteroid therapy.	11162997
Communicable Diseases, Keratitis	Altered Intercellular Communication	The intraocular portion of the infection responded quickly to intravitreal antifungal treatment; however, the course was prolonged by smoldering corneal inflammation.	11162997
allergic inflammation, Bronchial Hyperreactivity, Job Syndrome	Altered Intercellular Communication	Effects of Mycobacterium bovis BCG on the development of allergic inflammation and bronchial hyperresponsiveness in hyper-IgE BP2 mice vaccinated as newborns.	11163672
allergic inflammation, Bronchial Hyperreactivity	Altered Intercellular Communication	We tested the hypothesis that BCG vaccination in Th-2-susceptible newborn BP2 mice blocks allergic inflammation and bronchial hyperreactivity (BHR).	11163672
Bronchitis	Altered Intercellular Communication	Compared to OVA-challenged unvaccinated mice, those that received BCG 8 weeks before challenge developed intense bronchial inflammation, BHR, and high IgE titers.	11163672
Inflammation	Altered Intercellular Communication	Inflammation involved T cells, macrophages, dendritic cells and was accompanied by increased levels of Interleukin-5 (IL-5) in the bronchoalveolar lavages (BAL).	11163672
allergic inflammation	Altered Intercellular Communication	We demonstrate that 16 weeks after vaccination with BCG in newborn BP2 mice which have a high Th-2 background, allergic inflammation and BHR were blocked, even though a clear Th-1 shift was not achieved.	11163672
Inflammation, Data types - Address	Altered Intercellular Communication	These results indicate (i) the existence of an acute phase response followed by a chronic inflammation in AD, and (ii) that lithostathine and PAP are involved even at the first pre-clinical biochemical events of AD.	11164279
Inflammation	Altered Intercellular Communication	These factors are co-ordinately responsible for a huge range of extracellular signalling molecules responsible for inflammation, tissue remodelling, oncogenesis and apoptosis, progessess that orchestrate many of the degenerative processess associated with ageing.	11164475
Tissue injury, Burn injury	Altered Intercellular Communication	In this study we seek the divergent roles in relation to tissue injury between the neurotransmitters within 24 h after burn injury.	11164660
Communicable Diseases, Hepatic inflammation, Hepatitis C, Hepatitis, Chronic	Altered Intercellular Communication	Serum iron indices as a measure of iron deposits in chronic hepatitis C. Serum iron indices are believed to be elevated in patients with hepatitis C virus (HCV) infection in connection to the presence of hepatic inflammation, though this hypothesis has never been formally tested.	11165198
Fibrosis Assessment, Hepatic inflammation, Hepatitis C, Necrosis	Altered Intercellular Communication	In conclusion, in hepatitis C, serum iron reflects the degree of current hepatic inflammation and necrosis, whereas the extent of progressive deposition of iron in sites of fibrosis is best reflected by serum ferritin.	11165198
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Using a cDNA microarray representing 6794 distinct human genes, we identified candidate genes whose expression is altered in cerebral cortex of cases of early Alzheimer's disease (AD); among these was the synaptic vesicle protein synapsin II, which plays an important role in neurotransmitter release.	11165439
Inflammation, Coronary heart disease	Altered Intercellular Communication	Role of novel markers of inflammation in patients with stable coronary heart disease.	11165957
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	The role of novel markers of inflammation in patients with coronary heart disease (CHD) is still unclear.	11165957
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	We conducted a case-control study to assess the association between various markers of inflammation and the presence and severity of chronic stable CHD.	11165957
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	All markers of inflammation were highly significantly elevated (all p <0.005) in patients with stable CHD compared with controls.	11165957
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	The combination of > or = 2 markers of inflammation was associated with a strongly increased risk of CHD.	11165957
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	These results document an independent association between most of the markers of inflammation and chronic CHD, even in clinically stable patients.	11165957
Inflammation, Dysplasia, Papilloma	Altered Intercellular Communication	For each case the patient's sex and age, number of papillomas/patient, seasonal debut, duration, number of recurrences, localisation and presence of dysplasia andlor inflammation in the papilloma were registered.	11167228
Pancreatitis, Acute, Inflammation	Altered Intercellular Communication	Because severe acute pancreatitis is characterized by the development of systemic inflammation the authors studied whether procalcitonin, a marker of systemic inflammation, differentiated between patients with mild and severe acute pancreatitis.	11167871
Inflammation, Drug Implant, Osteopenia, Neoplasms	Altered Intercellular Communication	Five causes for implant loss could be detected: lacking primary osseointegration, acute inflammation, bone loss, biomechanical overloading and tumor recurrence.	11168242
Communicable Diseases, Inflammation	Altered Intercellular Communication	The tissue at the latter implant showed signs of infection and inflammation during the healing phase.	11168266
Inflammation	Altered Intercellular Communication	Interleukin-6 (IL-6) is a multifunctional cytokine that plays roles in the immune response, inflammation and hematopoiesis.	11168500
Stomatitis, Inflammation, Disease	Altered Intercellular Communication	These findings suggest a relationship between the expression of laminin (alpha1) and type IV collagen and the development of denture stomatitis, a disorder involving modification of soft tissues in which initial inflammation of the palatal mucosa results from stress under the denture.	11168854
Inflammation, Amyloidosis, Chronic inflammatory disorder	Altered Intercellular Communication	Increased cell-associated levels of biologically active mIL-1beta in circulating PBMCs represent a state of inflammation that may contribute to chronic inflammatory diseases such as beta2-microglobulin amyloidosis.	11169027
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Replacement of Cuprophan by synthetic membranes normalizes PBMC function and reduces the state of inflammation in ESRD patients.	11169027
Inflammation, Arthritis, Destruction (action)	Altered Intercellular Communication	MRI seems to be valuable as a marker of inflammation, destruction and, perhaps, as a predictor of therapeutic outcome in arthritis.	11171684
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Therefore, upregulation of IL-16 expression seems to be specific for chronic intestinal inflammation and could lead to increased secretion of other proinflammatory cytokines in IBD.	11171821
Inflammation	Altered Intercellular Communication	CMUSE is an independent entity characterised by steroid sensitive inflammation of the small bowel which often recurs after surgery.	11171822
Inflammation, Myositis, CTCAE 5.0	Altered Intercellular Communication	To investigate whether the combination of intravenous immunoglobulin (IVIg) with prednisone improves muscle strength and alters endomysial inflammation in patients with sporadic inclusion body myositis (s-IBM).	11171896
Dysarthria, CTCAE, Hypothyroidism	Altered Intercellular Communication	Dysarthria may be the leading symptom of hypothyroidism and can be promptly resolved after hormone substitution.	11172218
Inflammation, Tissue injury	Altered Intercellular Communication	Group II phospholipase A(2) (PLA(2)) is thought to play an important role in inflammation and tissue injury.	11173782
Celiac Disease, Abnormality of exocrine pancreas physiology	Altered Intercellular Communication	The abnormal exocrine pancreatic function found with an indirect test in patients with TS is probably secondary to a low pancreatic hormonal stimulation due to intestinal damage, as occurs in celiac sprue.	11173897
allergic inflammation, Atopy	Altered Intercellular Communication	IgE and mast cell chymase (MCC) play a key role in atopic or allergic inflammation of the skin.	11173969
Inflammation	Altered Intercellular Communication	The plasma levels of the soluble form of these molecules may be elevated in chronic inflammation.	11174343
Carditis, Certified Midwife	Altered Intercellular Communication	Inflammation of CM, irrespective of its exact anatomic location, was defined as carditis and classified as acute or chronic based on the number of inflammatory cells present.	11176074
Inflammation, Certified Midwife	Altered Intercellular Communication	In all cases, CM showed significant chronic inflammation.	11176074
Inflammation, Certified Midwife	Altered Intercellular Communication	Patients with severe chronic inflammation in CM had a significantly higher acid exposure of the lower esophagus as quantitated by a 24-hour pH test than those with mild chronic inflammation in CM.	11176074
Inflammation, Certified Midwife	Altered Intercellular Communication	Acute inflammation was uncommon in CM; it was present in only 26 of 141 (18.4%) patients.	11176074
Inflammation, Certified Midwife	Altered Intercellular Communication	There was no significant difference in acid exposure of the lower esophagus between patients with and without acute inflammation in CM.	11176074
Gastritis, Inflammation, Infection caused by Helicobacter pylori, Certified Midwife	Altered Intercellular Communication	The presence of acute inflammation in CM was significantly associated with distal gastritis and H. pylori infection.	11176074
Inflammation, Gastritis, Certified Midwife	Altered Intercellular Communication	This difference was greatest in men with severe inflammation in CM who had no evidence of distal gastritis.	11176074
Inflammation, Carditis, Certified Midwife	Altered Intercellular Communication	These findings provide evidence that chronic inflammation in CM is strongly associated with acid reflux and that H. pylori is not a significant etiologic factor in carditis.	11176074
Communicable Diseases, Helicobacter-associated gastritis, Inflammation, Certified Midwife	Altered Intercellular Communication	They also show that in patients with CM in whom H. pylori gastritis develops, the infection frequently spreads to involve CM, resulting in acute inflammation with neutrophils that is superimposed on the chronic inflammation already present.	11176074
Inflammation, Pancreatitis	Altered Intercellular Communication	To investigate whether marker(s) of systemic inflammation detect, at an early stage of acute pancreatitis, patients who may ultimately develop severe disease.	11176162
Inflammation	Altered Intercellular Communication	The extrapleural space with intermediate attenuation may indicate ongoing inflammation.	11176286
Epithelial Damage, allergic inflammation	Altered Intercellular Communication	The increased thickness in the fluticasone treatment may represent repair from epithelial damage caused by chronic allergic inflammation.	11177038
Inflammation	Altered Intercellular Communication	Suspected infection/inflammation and unobtainable/abnormal tympanograms, each accounted for 43 per cent of reasons for referral.	11177362
Inflammation, Squamous cell carcinoma, "Marjolins ulcer	Altered Intercellular Communication	'Marjolin's ulcer' is a term that has come to be used for epidermal squamous cell carcinomas that have developed in areas of chronic inflammation.	11177375
Inflammation, Anorexia	Altered Intercellular Communication	The main side effects were the IFN-related flulike syndrome (79%), increase in serum alanine aminotransferase (ALT) (28%), anorexia (19%), and mild inflammation at the injection site (19%).	11177578
Degenerative polyarthritis, Inflammation, Refractory anemias	Altered Intercellular Communication	In all OA synovium there was intense TSG-6 expression throughout the intimal layer, whereas in RA staining in this region was generally less pronounced and was absent at the synovial surface in tissues exhibiting significant inflammation.	11178946
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	There is increasing evidence that chronic obstructive pulmonary disease (COPD) is associated with chronic inflammation in the airways and lung parenchyma; however, little is known about the inflammatory response during acute COPD exacerbation.	11179105
ARCN1 gene, Inflammation, Virus Diseases	Altered Intercellular Communication	The objectives of this study were (1) to determine if inflammatory markers associated with neutrophilic inflammation and activation increase at times of acute COPD exacerbation relative to the clinically stable state, and (2) to determine whether the presence of acute bacterial or viral infection at the time of COPD exacerbation could be correlated with increases in sputum markers of inflammation.	11179105
ARCN1 gene, Airway structure	Altered Intercellular Communication	We conclude that markers of airway neutrophilic inflammation increase at the time of acute COPD exacerbation and then decline 1 mo later, and that this acute inflammatory response appears to occur independently of a demonstrable viral or bacterial airway infection.	11179105
Drug abuse, Inflammation, Fever, CTCAE, Anemia	Altered Intercellular Communication	A 35 year old woman with a long history of intravenous drug abuse presented to a local hospital with severe anaemia, fever, raised markers of inflammation, and positive blood cultures for Staphylococcus aureus.	11179283
Inflammation, Dysplasia, Anemia, Pernicious, Intestinal metaplasia, Atrophic, Lymphoid nodule	Altered Intercellular Communication	The frequency of fundal inflammation, atrophy, intestinal metaplasia, lymphoid follicle, and dysplasia and antral intestinal metaplasia and mild antral dysplasia were found to be higher in those in the pernicious anemia group than in the nonulcer dyspeptic patients.	11179986
Inflammation, Dysplasia, Atrophic	Altered Intercellular Communication	Antral inflammation, atrophy, and moderate and severe antral dysplasia were found to be higher in those in the nonulcer dyspeptic group.	11179986
Nephritis	Altered Intercellular Communication	It is concluded that renal inflammation in WG is associated with the induction of iNOS in inflammatory cells and the formation of nitrotyrosines.	11180170
Inflammation, Atherosclerosis, Tissue injury, Atherosclerosis of aorta, Malt Grain	Altered Intercellular Communication	This study reveals a close resemblance between adventitial lymphoid infiltrates in advanced atherosclerotic aortic disease and MALT, suggesting local generation of a humoral immune response, likely to be initiated by antigens released during a process of long-standing tissue injury and inflammation as part of advanced atherosclerosis.	11180175
Wallerian Degeneration, Inflammation, Polyneuropathy	Altered Intercellular Communication	Electrodiagnostic studies indicated an acute axonal polyneuropathy and sural nerve biopsy revealed acute wallerian degeneration without inflammation.	11180212
Inflammation, septic	Altered Intercellular Communication	We studied whether urinary excretion of BOMs would increase under septic conditions in humans and compared BOM levels with other well-established clinical parameters of inflammation.	11180995
Cessation of life, Inflammation, Dental Plaque	Altered Intercellular Communication	Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization.	11181465
Inflammation	Altered Intercellular Communication	Systemic chronic inflammation has been found to be related to all-cause mortality risk in older persons.	11181468
Ulcerative Colitis	Altered Intercellular Communication	In addition to the expected upregulation of various cytokine and chemokine genes, novel immune function-related genes such as IGHG3, IGLL2 and CD74, inflammation-related lipocalins HNL and NGAL, and proliferation-related GRO genes were over-expressed in UC.	11181568
Inflammation	Altered Intercellular Communication	Scleroderma "en coup de sabre": pathological evidence of intracerebral inflammation.	11181863
Airway structure	Altered Intercellular Communication	A potentially important role for ovarian hormones has been implicated in airway inflammation but the cellular target for such action is not known.	11182013
Nasal Polyps, Asthma	Altered Intercellular Communication	Nasal polyposis often coexists with asthma in airway inflammatory conditions characterised by the infiltration of a range of immune cells.	11182013
Airway structure	Altered Intercellular Communication	A potentially important role for ovarian hormones has been implicated in airway inflammation but the cellular target for such action is not known.	11182013
Inflammation	Altered Intercellular Communication	They also had lower biologic markers of inflammation.	11182025
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	In the 8 cases without cancer, both the prostatic glands and their surrounding stroma were positive for PD-ECGF only when they were accompanied by inflammation.	11182368
Inflammatory abnormality of the eye	Altered Intercellular Communication	This decrease may reflect a tendency for systemic medications to prevent the development of ocular inflammation.	11182663
Inflammation	Altered Intercellular Communication	The emergence of new therapeutic agents to control inflammation may continue to reduce the costs of treating this important disease.	11184066
Hepatic inflammation, Exacerbation of cGVHD	Altered Intercellular Communication	Clinicians should consider the risk of inducing serious flares in hepatic inflammation as a result of abrupt nucleoside analogue withdrawal.	11185539
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	We assessed plasma neopterin level as a marker of inflammation in Alzheimer disease (AD).	11186601
Inflammation	Altered Intercellular Communication	The difference between the groups seemed to correlate with the degree of past preoperative inflammation.	11188997
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	The appendix in this case showed only focal inflammatory change, which differs from what occurs in acute appendicitis, where diffuse inflammation of the appendix is usually noted.	11190382
Communicable Diseases, Inflammation, Perforation (observation)	Altered Intercellular Communication	Histopathological analysis of the appendix documented no acute inflammation in 28.8%, the perforation rate was 8.3% and the wound infection rate 9.6%.	11190643
Inflammation, Infection, Perforation (observation)	Altered Intercellular Communication	In the second period (1996/97), 2,430 patients were treated conservatively (32.8%), in 24.9% of all operated cases, the histopathological examination shows no acute inflammation of the appendix, the perforation rate was 5.9% and the rate of wound infections 2.5%.	11190643
Inflammation, Waldenstrom Macroglobulinemia, Fibrosis Assessment	Altered Intercellular Communication	Histological examination revealed chronic inflammation with lymphoplasmacytic infiltrate and fibrosis of both intraosseous mass and dural invasive lesion.	11193544
Inflammation, Fracture, Pacchionian granulation	Altered Intercellular Communication	We considered that the incipient intraosseous mass resulted from a response of the marrow by destructive progression of chronic inflammation passed through the fracture crack or the cavity of arachnoid granulation.	11193544
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Involvement of peripheral polymorphonuclear leukocytes in oxidative stress and inflammation in type 2 diabetic patients.	11194213
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	To determine the extent to which peripheral polymorphonuclear leukocytes (PMNs) contributed to oxidative stress (OS) and inflammation in type 2 diabetic patients.	11194213
Inflammation, Vascular Diseases, Atherosclerosis, Diabetes Mellitus, Endothelial dysfunction	Altered Intercellular Communication	Understanding the contribution of PMNs to OS and inflammation in diabetes may illuminate new mechanisms through which endothelial dysfunction evolves and causes angiopathy and atherosclerosis.	11194213
Refractory anemias, Inflammation	Altered Intercellular Communication	These data suggest IL-16 might play a role in the pathogenesis of chronic inflammation in RA.	11196512
Refractory anemias, Inflammation	Altered Intercellular Communication	The lack of significant correlation between IL-16 expression, clinical disease activity, and local inflammatory activity suggests a regulatory rather than a proinflammatory function for IL-16 in the pathogenesis of chronic synovial inflammation in RA.	11196512
Inflammation, Decalcification	Altered Intercellular Communication	This demineralization was not related to the indices of inflammation or disease duration, but there is a delayed correlation with HAQ score, as well as age and the number of years since menopause.	11196516
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Magnetic resonance imaging: a valuable method for the detection of synovial inflammation in rheumatoid arthritis.	11196540
Refractory anemias, Inflammation, Joints, Synovitis	Altered Intercellular Communication	MRI is more sensitive than clinical examination to detect synovitis of hands and wrists in RA, especially for MCP and PIP joints, and is valuable for assessment of inflammation in hands and wrists in RA.	11196540
Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	Plasma monocyte chemoattractant protein 1 is a marker for joint inflammation in rheumatoid arthritis.	11196541
Refractory anemias, Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	Monocyte chemoattractant protein 1 (MCP-1) level in plasma is described as a marker for joint inflammation in rheumatoid arthritis (RA).	11196541
Refractory anemias, Inflammation	Altered Intercellular Communication	MCP-1 appears to participate in the disease process in RA, and plasma MCP-1 may be useful in monitoring joint inflammation.	11196541
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The hallmarks of the chronic cutaneous involvement in this syndrome are inflammation and fibrosis of the fascia.	11196547
Intestinal metaplasia, Inflammation, Intestinal Cancer, Gland	Altered Intercellular Communication	Glandular atrophy and intestinal metaplasia, which occur in gastric mucosa with chronic inflammation, are significantly associated with intestinal-type cancer.	11197045
Inflammation, Neoplasms	Altered Intercellular Communication	The tumor was resected via bronchoscopy, which revealed histologically small cell carcinoma with significant inflammation and scar formation.	11197831
Neoplasms	Altered Intercellular Communication	The role of pregnancy and its associated hormonal profiles on tumour growth is discussed.	11198773
Communicable Diseases, Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	A prospective study of genetic markers of susceptibility to infection and inflammation, and the severity, progression, and regression of coronary atherosclerosis and its response to therapy.	11199329
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a key role in susceptibility to coronary atherosclerosis and response to therapy.	11199329
Acute and chronic inflammation	Altered Intercellular Communication	Recent aetiological hypotheses have claimed that the origin of the lesion may be related to Brunn's nest hyperplasia and/or to chronic urothelial inflammation.	11200008
Gastrointestinal inflammation	Altered Intercellular Communication	The gastrointestinal inflammation resolved by 3 and 1/2 years of age.	11200486
Inflammation, Thyroid dysfunction	Altered Intercellular Communication	Therefore, in the elderly without clinically or biochemically overt thyroid dysfunction, positive TgAb and/or TPOAb could imply presence of FLT, and their titers might reflect degree of inflammation.	11200938
Asthma, Upper Respiratory Infections	Altered Intercellular Communication	[Hydrogen peroxide--a marker for respiratory tract inflammation in patients with bronchial asthma].	11201826
Asthma, Upper Respiratory Infections	Altered Intercellular Communication	To test H2O2 as a marker of respiratory tract inflammation in patients with bronchial asthma (BA).	11201826
Upper Respiratory Infections	Altered Intercellular Communication	It was proved possible to use H2O2 in CEA for evaluation of respiratory inflammation in BA patients.	11201826
Asthma, Bronchitis	Altered Intercellular Communication	The cause of asthma which has been linked to a chronic, T-cell-mediated bronchial inflammation, remains unclear.	11203358
Dental Plaque, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Following the intervention, a statistically significant improvement was recorded for changes in oral mucosal color, a modified plaque index which measured oral hygiene status, and a mucosal index which recorded mucosal inflammation.	11203883
Inflammation	Altered Intercellular Communication	We conclude that both leukocyte and erythrocyte aggregation occur in the peripheral blood of patients with infection/inflammation.	11204542
Inflammation, Crohn Disease	Altered Intercellular Communication	Secretory group IIa phospholipase A2 (PLA2-II) is an important regulator of proinflammatory lipid mediator production and may play a role in ileal inflammation in Crohn's disease.	11205686
Crohn Disease, Inflammation	Altered Intercellular Communication	However, one characteristic feature of Crohn's disease is the transmural inflammation.	11205686
Hyperaldosteronism, Renal vascular disorder	Altered Intercellular Communication	Hormonal investigation revealed secondary aldosteronism and positive captopril test for renovascular disease.	11206681
Airway structure, Respiration Disorders	Altered Intercellular Communication	Induced sputum is increasingly used to detect and monitor airway inflammation in respiratory diseases.	11207017
Inflammation, Duodenal Ulcer, Tuberculosis, Granuloma	Altered Intercellular Communication	Biopsy samples obtained from the duodenal ulcer at the second upper gastrointestinal endoscopy showed chronic inflammation with an epithelioid granuloma, suggesting tuberculosis.	11207910
Inflammation	Altered Intercellular Communication	The evaluation included the presence of chronic inflammation of gastric mucosa, its activity and intensity.	11208366
Inflammation, Food Allergy, Atopy, Colonization	Altered Intercellular Communication	Significant differences were found concerning inflammation intensity in atopic patients additionally infected with H. pylori, in comparison with the group of patients with food allergy without bacterial colonization.	11208366
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	Moreover, statistically significant differences were found in the inflammation intensity between the examined group and the control group with no symptoms of allergy.	11208366
Helicobacter pylori, Gastritis, Atopy	Altered Intercellular Communication	In atopic patients infected with Helicobacter pylori, a long-term exposure to food allergens increases the intensity of gastric mucosa inflammation.	11208366
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In the histopathological picture of the liver predominated minimal or moderate inflammation activity (grading: 1--in 50%, 2--in 46.6%, 3--in 3.4%) and little fibrosis (staging: 0--in 80%, 1--in 13.3%, 2--in 6.7%).	11208439
Allergic, Inflammation, Infection caused by Helicobacter pylori, Atopy, Communicable Diseases, Chronic gastritis	Altered Intercellular Communication	In atopic subjects with chronic gastritis and H. pylori infection, the increase in IL-4, IL-5, IL-8 and TNF alpha levels suggests that both infectious and allergic factors play an important role in the pathogenesis of inflammation.	11208468
Inflammation, Food Allergy, Gastritis	Altered Intercellular Communication	Statistical analysis of the incidence of these signs of inflammation in patients with food allergy did not show significant differences in relation to subjects with non-atopic gastritis.	11208480
Inflammation	Altered Intercellular Communication	In laboratory results we found nonspecific signs of inflammation.	11208510
Neurogenic Inflammation, Pruritus, Erythema	Altered Intercellular Communication	After cessation of the symptoms of neurogenic inflammation, such as burning sensations or erythema, all of them experienced a complete elimination of pruritus within 12 days.	11209117
Inflammation, immunoglobulin A	Altered Intercellular Communication	CagA-positive H. pylori strains seem to induce an immune response with a markedly higher frequency of IgA than what is found in inflammation caused by CagA-negative strains.	11209973
Inflammation	Altered Intercellular Communication	The presence of PAF was associated with histopathological findings of local inflammation and increased blood vessel density.	11210074
Gingivitis	Altered Intercellular Communication	The risk for severe gingival inflammation and/or increased probing depth was 1.5 and 5.2 times higher if a positive BANA test or A. actinomycetemcomitans test was found in a particular site.	11210274
Inflammation, Dysplasia	Altered Intercellular Communication	In HPs without dysplasia, size was correlated positively with the degree of stromal inflammation and with p53 and cyclin D1 expression.	11211611
Refractory anemias, Inflammation	Altered Intercellular Communication	Perivascular infiltration by DC, lymphocytes, and macrophages is nonspecifically related to inflammation, but signals present in RA and SpA ST lead to more intense cellular infiltration and accumulation.	11212147
ENL Protein, Inflammation	Altered Intercellular Communication	It has been suggested that erythma nodosum leprosum (ENL) is associated with enhanced production of TNF-alpha resulting in increased inflammation of the skin and nerve function impairment.	11212480
Necrotizing granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	Although the aetiology of sarcoidosis remains unclear, sarcoid granulomatous inflammation is marked by predominant expression of T-helper cell 1 cytokines, with reduced expression of T-helper cell 2 cytokines.	11213374
Bacteremia, Inflammation, Pituitary Adenoma	Altered Intercellular Communication	It is most likely that the tooth extraction caused a bacteremia, which led to an inflammation with abscess formation within the pituitary adenoma.	11213976
Helicobacter pylori	Altered Intercellular Communication	It may be stated that in patients with non-specific inflammations of the gut there is a lower incidence of Helicobacter pylori than in the general population, in particular those subjects who were or are treated with Sulfasalazine.	11214362
Inflammation, Necrosis	Altered Intercellular Communication	In the last two biopsies (days 50 and 64 from onset) active inflammation and myocyte necrosis were absent.	11214703
Myocarditis, Dilated Cardiomyopathy Pathway, Myocarditis, CTCAE 5.0, Inflammatory disorder	Altered Intercellular Communication	The major conclusions to be drawn from this case are: 1) the aspecific pathologic findings of dilated cardiomyopathy patients may result from an acute myocardial inflammation; 2) immediate endomyocardial biopsy in patients with clinically diagnosed myocarditis minimizes the risk of missing the diagnosis of inflammatory disease; to this aim a precise definition of "early onset" is especially needed; 3) LVAD support may contribute to the morphological recovery of severely damaged myocytes.	11214703
Adenolymphoma, Inflammation, Squamous metaplasia, Necrosis	Altered Intercellular Communication	We describe a case of an extirpated Warthin's tumor of the right parotid gland which demonstrated extensive necrosis, squamous metaplasia and xanthomatous inflammation.	11215113
Inflammation, Helicobacter pylori Positive	Altered Intercellular Communication	Body inflammation was also significantly higher in the histologically Helicobacter pylori-positive group (chronic inflammation: 1.43+/-0.2 vs 1.05+/-0.06; p=0.0271; inflammation acitivity: 0.	11215554
Hepatic inflammation	Altered Intercellular Communication	Early mutation of precore (A1896) region prior to core promoter region mutation leads to decrease of HBV replication and remission of hepatic inflammation.	11215741
Edema, Vascular System Injuries	Altered Intercellular Communication	In addition to the inhibition of serum protein-mediated coagulation, heparin inactivates or prevents the release of mediators of vascular injury inflammation, permeability, and edema.	11215838
Hormone abnormality, Heart failure, Liver Dysfunction, Diabetes Mellitus	Altered Intercellular Communication	Liver dysfunction or hormonal disorders such as diabetes generally precede cardiac failure.	11216822
Periodontal Diseases, Inflammation, Bacterial Infections, Cardiovascular Diseases	Altered Intercellular Communication	Periodontal disease, the result of a complex interplay of bacterial infection and chronic inflammation, has been suggested to be a predictor of cardiovascular disease.	11216961
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	The thin nature of the eyelid makes it susceptible to inflammation resulting from allergy.	11217004
Inflammation, Malnutrition, Hypoalbuminemia	Altered Intercellular Communication	Although hypoalbuminemia has been attributed to malnutrition, it has recently been recognized evidence of inflammation that predicts serum albumin concentration in dialysis patients.	11217649
HD Term Type, Malnutrition, Inflammation	Altered Intercellular Communication	Low serum albumin in HD patients is principally associated with infection/inflammation but not with malnutrition.	11217649
HD Term Type, Inflammation	Altered Intercellular Communication	CRP is a sensitive marker of inflammation and an power predictor of mortality in HD patients.	11217649
Airway structure, Bronchitis	Altered Intercellular Communication	In patients with chronic bronchitis a four week trial with inhaled steroids does not attenuate airway inflammation.	11217907
Airway structure, Bronchitis	Altered Intercellular Communication	chronic bronchitis with mild or no airflow obstruction, a trial with inhaled steroids could reveal potential benefits, particularly in terms of a modulation of airway inflammation.	11217907
Mucous Membrane, Inflammation	Altered Intercellular Communication	Triple site biopsy specimens were taken from antrum, corpus, and supraangle simultaneously in 3002 Japanese cases to compare the differences among the biopsy sites for the evaluation of mucosal atrophy and inflammation.	11218394
Intestinal metaplasia, Inflammation, Infection caused by Helicobacter pylori, Mucous Membrane	Altered Intercellular Communication	Our results indicate that the antral and the corpal biopsy are suitable for the evaluation of inflammation and H. pylori infection, but the supraangular biopsy is more reliable for the recognition of mucosal atrophy and intestinal metaplasia than the antral and the corpal biopsy.	11218394
Esophageal motility disorders, Systemic Scleroderma	Altered Intercellular Communication	Recent studies suggest that esophageal dysmotility occurring in systemic sclerosis might be caused by neurotransmitter levels decrease.	11220202
Cataract, Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	We used a laser-flare meter to compare inflammation of the anterior chamber in combined cataract and glaucoma surgery with that in pure filtering surgery.	11220271
Hypergastrinemia (finding)	Altered Intercellular Communication	When hormonal cause of ulcerogenesis was suspected, even in unknown origin of hypergastrinemia, the extirpation of gastric stump is indicated.	11220910
Intraocular inflammation, Traumatic injury, Hemangioma of retina	Altered Intercellular Communication	A 36-year-old Taiwanese male, who denied any history of ocular trauma, intraocular inflammation or surgery, had a macular pucker associated with a peripheral retinal angioma.	11221549
Liver Abscess, Leucocytic infiltrate, Inflammation	Altered Intercellular Communication	Pathologic examination of two patients showed marked inflammatory cell infiltration with stenosis of portal venules within the portal tracts surrounding hepatic abscesses without definite inflammation in the liver parenchyma.	11222204
Liver Abscess, Inflammation	Altered Intercellular Communication	Segmental hepatic enhancement on dynamic CT is frequently associated with hepatic abscesses and may be caused by decreased portal flow resulting from inflammation of the portal tracts.	11222204
Inflammation, Chronic infectious disease, Atherosclerosis	Altered Intercellular Communication	Markers of systemic inflammation, such as soluble adhesion molecules and circulating bacterial endotoxin, and levels of soluble human heat-shock protein 60 and antibodies to mycobacterial heat-shock protein 65 were elevated in subjects with chronic infections and predictive of an increased risk of atherosclerosis.	11222467
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Induction of systemic inflammation and autoimmunity may be potential pathophysiological links.	11222467
Inflammation, Data types - Address	Altered Intercellular Communication	Our data demonstrate that ACT promotes amyloid deposition and provide a specific mechanism by which inflammation and the subsequent upregulation of astrocytic ACT expression in AD brain contributes to AD pathogenesis.	11222634
Inflammation, Calcinosis	Altered Intercellular Communication	Tympanosclerosis is a condition leading to a calcification process in the middle ear, and often develops after chronic inflammation of the middle ear.	11223300
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	These results suggest that higher WBC counts are a predictor of CHD mortality independent of the effects of smoking and other traditional CVD risk factors, which may indicate a role for inflammation in the pathogenesis of CHD.	11223329
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Additional studies are needed to determine whether interventions to decrease inflammation can reduce the risk for CHD associated with elevated WBC.	11223329
Hypercholesterolemia, Inflammation, Atherosclerosis	Altered Intercellular Communication	Our findings would support the hypothesis that patients with isolated hypercholesterolemia and without clinical atherosclerosis may be silent carriers of arterial subendothelial inflammation, expressed as an increase of sICAM-1.	11223435
Inflammation, Neoplasms	Altered Intercellular Communication	The existence of inflammation close to tumour is interesting to emphasize.	11223562
Airway structure, Asthma	Altered Intercellular Communication	Increased concentrations of exhaled nitric oxide (NO) correlate with increased airway inflammation and measurement of exhaled NO is a noninvasive method for the management of bronchial asthma.	11223729
Heart Diseases, Inflammation, Bronchial Hyperreactivity	Altered Intercellular Communication	These results indicate that bronchial hyperresponsiveness in patients with cardiac diseases is not a consequence of eosinophilic inflammation or of exhaled NO.	11223729
AHR wt Allele	Altered Intercellular Communication	In this case, it is suggested that asthma-like symptoms were due to localized airflow limitation in the right bronchus as well as to AHR associated with diffuse airway neutrophilic inflammation.	11223741
Inflammation, Purulence, Serous	Altered Intercellular Communication	Wounds were considered infected if purulence discharged from the wound, or possibly infected if signs of inflammation or a serous discharge developed.	11224630
Inflammation	Altered Intercellular Communication	These were due to an inflammation of choroidal vessels of the right eye appearing as an initial sign of PAN.	11225400
Cataract, Inflammation, Nonproliferative diabetic retinopathy	Altered Intercellular Communication	To evaluate inflammation after cataract surgery in patients with nonproliferative diabetic retinopathy (NPDR) and compare results with 2 intraocular lenses (IOLs): a foldable hydrophobic acrylic and a heparin-surface-modified (HSM) poly(methyl methacrylate) (PMMA).	11226788
Inflammation, Diabetic Retinopathy	Altered Intercellular Communication	Postoperative inflammation results indicate that the lenses are equally suitable for the use in patients with diabetic retinopathy.	11226788
Inflammation, Anterior scleritis	Altered Intercellular Communication	In five patients with various types of severe anterior scleritis a long-term high-dose steroid treatment failed to control scleral inflammation.	11227160
Inflammation, Complication Aspects	Altered Intercellular Communication	Scleral inflammation and ocular complications were controlled in all patients by a regimen of systemic CsA combined with a low maintenance steroid dose below the Cushing threshold.	11227160
allergic inflammation	Altered Intercellular Communication	During inflammatory states, airway epithelial cells are stimulated by various proinflammatory mediators to synthesize paracrine mediators including prostaglandin E2, which likely contributes to the recurrence of allergic inflammation.	11227912
Asthma, Allergy - Charge Type Reason	Altered Intercellular Communication	In conclusion, these data provide evidence that the interplay of nerve fibers and airway epithelial cells is likely important in inflammatory conditions as, e.g., allergy and asthma.	11227912
Chorioretinal scar, Vasculitis, CTCAE, Pseudocoarctation, Intraocular inflammation	Altered Intercellular Communication	To describe and evaluate the cause of a clinical entity characterized by bilateral intraocular inflammation, multiple arterial ectasias including beading, macroaneurysms, comma-like ectasias and kinking, with vasculitis, staining of the optic disk and multiple peripheral round punched-out hypopigmented chorioretinal scars in elderly patients.	11228299
Inflammation, Pathological Dilatation	Altered Intercellular Communication	In two patients, an arterial ectasia developed at the site of previous focal inflammation.	11228299
Inflammation, Hypertension, CTCAE, Pathological Dilatation	Altered Intercellular Communication	Arterial hypertension may play a role in the formation of the ectasias by increasing the pressure on the arterial wall weakened by inflammation.	11228299
Inflammation, Fibrosis Assessment, Fatty degeneration, Liver Cirrhosis	Altered Intercellular Communication	Liver biopsy showed steatosis with inflammation in all, fibrosis in two and cirrhosis in one patient.	11229116
Inflammation, Functional Disability	Altered Intercellular Communication	Disease outcome was assessed at 3 years, using measures of joint inflammation, functional disability, and radiologic damage.	11229462
Inflammation	Altered Intercellular Communication	The patient was treated with 4 weeks of appropriate antibiotics, and the synovial inflammation resolved.	11230461
Cessation of life, Inflammation, Malnutrition, Hypoalbuminemia	Altered Intercellular Communication	Hypoalbuminemia strongly predicts death in hemodialysis patients and results from both inflammation and malnutrition.	11231368
Inflammation, Malnutrition, negative regulation of appetite	Altered Intercellular Communication	One potential link between malnutrition and inflammation is appetite suppression triggered by inflammation.	11231368
Inflammation	Altered Intercellular Communication	Leptin is not increased as a consequence of inflammation in hemodialysis patients, but behaves as a negative rather than as a positive acute phase protein.	11231368
Inflammation, Restenosis	Altered Intercellular Communication	Inflammation plays a pathogenic role in the development of restenosis after percutaneous transluminal coronary angioplasty (PTCA).	11231910
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Inflammation may play an important role in atherosclerotic disease.	11231928
Cessation of life, Cardiovascular Diseases	Altered Intercellular Communication	The results suggest that the incidence of cardiac events and death due to cardiovascular diseases in middle-aged men predicted by plasma levels of fibrinogen is modified by other inflammation-sensitive proteins.	11231928
Inflammation, Hepatitis B, Hepatitis C	Altered Intercellular Communication	In hepatitis B tissue lesions, genes involved in inflammation were predominant, whereas in hepatitis C, expression of anti-inflammatory response genes was relatively dominant.	11231949
Acute Lung Injury, Pneumonitis	Altered Intercellular Communication	These results document the functional duality of PMN in ALI by showing the participation of PMN in the modulation of lung inflammation.	11232634
Inflammation, Hematoma, Wound discharge finding, Penetrating aortic ulcer	Altered Intercellular Communication	It is assumed that the transmural oozing occurred after development of the penetrating aortic ulcer, which formed an extra-aortic hematoma and caused surrounding inflammation, and led to tracheal artery feeding.	11232996
Memory dysfunction	Altered Intercellular Communication	With increasing age women seem to suffer more often from chemosensory dysfunction than men, which may be related to hormonal factors.	11233469
Inflammation	Altered Intercellular Communication	That depended on the intensity of inflammation and vessel disturbances.	11236158
Inflammation	Altered Intercellular Communication	The increase of dimethyl sulphide contributed to oral malodor during periodontal inflammation.	11236158
Inflammation, Pain Distress Question	Altered Intercellular Communication	It may be suggested that thermal treatment, by reducing inflammation, reduced pain and therefore diminished the cause of stress.	11236389
Pancreatitis, Hypergammaglobulinemia	Altered Intercellular Communication	Sclerosing pancreatitis is a unique form of pancreatitis that is characterized by irregular narrowing of the main pancreatic duct, lymphoplasmacytic inflammation of the pancreas, and hypergammaglobulinemia and that responds to glucocorticoid treatment.	11236777
Squamous cell carcinoma, Keratitis, Perforation (observation), Neoplasms	Altered Intercellular Communication	To describe three cases of squamous cell carcinoma of the conjunctiva presenting with corneal and scleral inflammation, thinning, and perforation without any tumor formation.	11237910
Inflammation, Inflammatory abnormality of the eye, Interstitial keratitis	Altered Intercellular Communication	The subjects had symptoms of external ocular inflammation with focal corneal or scleral thinning and inflammation, as well as interstitial keratitis in two cases.	11237910
Inflammation, Necrosis	Altered Intercellular Communication	It seems that diffuse growth with inflammation leads to thinning, necrosis, and perforation of the ocular wall with resultant intraocular spread.	11237910
Inflammation, Squamous cell carcinoma, Perforation (observation), Cornea	Altered Intercellular Communication	Squamous cell carcinoma should be considered in the differential diagnosis of corneal and scleral thinning, perforation, and inflammation of unknown cause, especially in the older male subject.	11237910
Communicable Diseases, Primary malignant neoplasm, Inflammation, Hereditary hemochromatosis	Altered Intercellular Communication	"Diseased" subjects were defined as those with possible pathologically altered iron measures due to inflammation, infection, elevated liver enzymes, hereditary hemochromatosis, or cancer.	11237943
Inflammation, atherosclerotic	Altered Intercellular Communication	C-reactive protein (CRP) and complement are hypothesized to be major mediators of inflammation in atherosclerotic plaques.	11238052
Inflammation, Stasis dermatitis	Altered Intercellular Communication	Inflammation in stasis dermatitis upregulates MMP-1, MMP-2 and MMP-13 expression.	11240267
Polyp in nasopharynx	Altered Intercellular Communication	Morphological and clinical characteristics of antrochoanal polyps: comparison with chronic inflammation-associated polyps of the maxillary sinus.	11240321
Polyp in nasopharynx	Altered Intercellular Communication	to compare morphological and clinical features of antrochoanal polyps and chronic inflammation-associated polyps of the maxillary sinus.	11240321
Polyp in nasopharynx	Altered Intercellular Communication	histological and scanning electron microscopic examination of ten antrochoanal polyps and ten chronic inflammation-associated polyps of the maxillary sinus; comparison of clinical data in both groups of patients.	11240321
polyps, Cyst, Nasal obstruction present finding, Headache, Polyp in nasopharynx, Squamous metaplasia	Altered Intercellular Communication	the antrochoanal polyps differed from chronic inflammation-associated polyps of the maxillary sinus only in a few minor features; slightly longer duration of the process, lower incidence of maxillary ostial obstruction, higher incidence of frequent headaches, persistent nasal obstruction, presence of cysts in the polyp stroma, thickened basement membrane, lower incidence of squamous cell metaplasia, and higher proportion of migratory cells in nasal smears.	11240321
Polyp in nasopharynx	Altered Intercellular Communication	In spite of minor differences, antrochoanal polyps can be regarded as chronic inflammation-associated polyps with cystic origin and peculiar localization.	11240321
Inflammatory abnormality of the eye, Interstitial keratitis, Inflammatory disorder, Oculovestibuloauditory syndrome	Altered Intercellular Communication	Cogan's syndrome is an inflammatory disease that is characterized by ocular inflammation (typically interstitial keratitis) and is associated with Meniere-like vestibuloauditory dysfunction.	11240475
Deafness, Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation usually resolves after several weeks or months but deafness is often irreversible.	11240475
Inflammation, Fibrosis Assessment, Lung Injury, Silicosis	Altered Intercellular Communication	Pro-inflammatory cytokines, such as interleukin-1 (IL-1), play a key role in the development of silicosis by regulating mediators which are responsible for lung injury, inflammation, and potentially fibrosis.	11241561
Acute hepatitis	Altered Intercellular Communication	The correlation between patchy enhancement and acute liver inflammation was significant (P = 0.005).	11241811
Inflammation, Fibrocartilage, Neoplasms	Altered Intercellular Communication	Intraoperative findings and pathologic examination revealed degenerative fibrocartilage without inflammation or neoplasia.	11242280
Inflammation, Arteritis	Altered Intercellular Communication	The significance of perivascular inflammation in the absence of arteritis in temporal artery biopsy specimens.	11242789
Inflammation, Temporal Arteritis	Altered Intercellular Communication	We retrospectively compared 81 temporal artery biopsy specimens demonstrating perivascular inflammation without evidence of temporal arteritis and 76 specimens demonstrating no inflammation.	11242789
Inflammation, Temporal Arteritis	Altered Intercellular Communication	In patients with no evidence of inflammation (50 women; mean age, 66.6 years), 21 met ACR criteria for temporal arteritis.	11242789
Inflammation, Temporal Arteritis, Arteritis	Altered Intercellular Communication	Patients with chronic perivascular inflammation but no arteritis seem no more likely to have temporal arteritis on clinical grounds than similar patients without inflammation on biopsy.	11242789
Inflammation, Pericarditis, Constrictive	Altered Intercellular Communication	Precipitation of cholesterol crystals may occur and induce inflammation and constrictive pericarditis.	11242889
Inflammation	Altered Intercellular Communication	In turn, it may cause inflammation in such rapidly dividing tissues as the corneal epithelium, conjunctiva, and tear duct.	11243427
Inflammation	Altered Intercellular Communication	Inflammation may be exacerbated by pre-existing dermatologic conditions.	11243427
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The degree of inflammation and fibrosis correlated with the interval between CABG and pleural surgery.	11243959
Inflammation, Fibrous	Altered Intercellular Communication	Early post-CABG patients displayed more inflammation, with abundant lymphocytes in nodular configuration deep in the fibrous tissues away from the surface.	11243959
Inflammation, Fibrosis Assessment, Cholestasis	Altered Intercellular Communication	All patients met at least 1 of the following inclusion criteria: (1) moderate to severe inflammation (grade III to IV) on allograft biopsy, (2) bridging fibrosis on allograft biopsy, or (3) severe cholestasis attributable solely to HCV recurrence.	11244158
Inflammation, Neurotoxicity Syndromes	Altered Intercellular Communication	Nitric oxide, a noxious and free-radical gas, plays a key role in vasodilatation, inflammation, immunity, and neurotoxicity.	11244341
Inflammation, Swelling	Altered Intercellular Communication	Formation of an abscess did not occur despite marked focal inflammation and swelling of the muscle.	11245514
Communicable Diseases, Inflammation, atherosclerotic	Altered Intercellular Communication	Our data support the importance of chronic inflammation and infection for the early stages of atherosclerotic development.	11245642
Communicable Diseases	Altered Intercellular Communication	It has been described in relation to various insults, including a number of infectious and inflammatory conditions.	11245766
Chronic inflammation, Perforation (observation), Intervertebral Disk Displacement, Osteogenesis, Hypertrophy	Altered Intercellular Communication	This was caused by hypertrophy, with chronic inflammation and ossification of the posterior longitudinal ligament sustaining chronic mechanical irritation to the dura mater, leading to perforation of the herniated disc by an accidental force.	11246389
Inflammation	Altered Intercellular Communication	YKL-40 reflects the degree of inflammation rather than cartilage metabolism.	11246673
Inflammation	Altered Intercellular Communication	[Clinical effectiveness of Duracef in children with ENT inflammation].	11247242
Inflammation	Altered Intercellular Communication	106 children aged 4 to 14 years received duracef for different acute and chronic (exacerbation) ENT inflammation.	11247242
Inflammation	Altered Intercellular Communication	In acute inflammation use of duracef is beneficial as it is effective, inexpensive, low toxic, convenient in administration, is well tolerated, friendly to the intestine.	11247242
Inflammation	Altered Intercellular Communication	These results suggest that CD8+ cells may have a key role in local inflammation in SpAs.	11247858
Inflammation, Retinitis Pigmentosa, Crystal Structure	Altered Intercellular Communication	There was no accompanying inflammation and the posterior segments showed no evidence of crystalline deposits or retinitis pigmentosa, as is found in Bietti's dystrophy.	11248826
Inflammation, Fibrosis Assessment, Pancreatitis	Altered Intercellular Communication	Cytokines play an important role in the regulation of inflammation and fibrosis in the development of chronic pancreatitis.	11249075
Inflammation, Pancreatitis	Altered Intercellular Communication	These data indicate that TGFbeta may play an active role in the advancement of pancreatitis by causing local inflammation and inducing fibroblasts to secrete collagen.	11249075
Airway structure	Altered Intercellular Communication	Oxygen metabolites may play a direct or indirect role in the modulation of airway inflammation.	11249929
Herpes Simplex Infections, Inflammation	Altered Intercellular Communication	Is herpes simplex virus associated with pulp/periapical inflammation?	11250636
Airway structure, MS4A2 wt Allele	Altered Intercellular Communication	These diseases are characterized by airway inflammation with enhanced eosinophil activity, and the risk of disease development has been shown to increase with the prevalence of atopy.	11251402
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The molecules have specific functions during developmental processes as well as in diseases, such as cancer and inflammation.	11251555
Inflammation, Ulcer	Altered Intercellular Communication	The altered expression patterns of glypican and syndecan-1 and -4 in chronic ulcers reflect their possible roles during inflammation and cell proliferation.	11251555
Hormone abnormality, Neurologic Deficits	Altered Intercellular Communication	The patient was released from the hospital in good health without any neurological deficits and hormonal disorders.	11253469
Inflammation	Altered Intercellular Communication	In addition, we found correlations with clinical presentation, resting-ECG, body-mass-index and erythrocyte-sedimentation rate as a possible marker of inflammation in bypass-atherosclerosis.	11253630
Inflammation, Coronary heart disease	Altered Intercellular Communication	In view of the robust association between markers of inflammation, especially CRP, and risk of coronary heart disease, an anti-inflammatory action of alcohol could contribute to the link between moderate consumption and lower cardiovascular mortality.	11253971
Inflammation, Gastro-esophageal reflux disease with esophagitis	Altered Intercellular Communication	Prevalence of histological reflux oesophagitis in H. pylori positive patients: effect of density of H. pylori and activity of inflammation.	11255998
Inflammation, Esophagitis	Altered Intercellular Communication	In this prospective study we assessed the influence of H. pylori density and activity of inflammation in different parts of stomach on histological oesophagitis.	11255998
Inflammation	Altered Intercellular Communication	The activity and degree of inflammation was not significantly different in corpus-cardia pair.	11255998
Refractory anemias, Inflammation, Joint laxity	Altered Intercellular Communication	The aim of our study was to evaluate the influence of joint hypermobility on RA synovial fluid (SF) inflammation.	11257158
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is thought to play a central role in the etiology and outcome of atherosclerosis.	11257270
Inflammation, Chronic inflammatory disorder	Altered Intercellular Communication	There was no evidence that these inflammation phenotypes were linked to a microsatellite marker in the interleukin-1 gene cluster on chromosome 2q, a region that includes several candidate genes for chronic inflammatory diseases.	11257270
Tumor necrosis, Inflammation, Atherosclerosis	Altered Intercellular Communication	Tumor necrosis factor (TNF) is an important cytokine in the inflammation process of atherosclerosis and is also involved in lipid metabolism.	11257271
Inflammation, Granulomatous, Data Type -Character, Granuloma	Altered Intercellular Communication	Forty cases of granulomatous appendicitis were evaluated for histologic features including transmural inflammation, number and character of granulomas, and mucosal changes.	11257626
Granuloma, Inflammation, Cryptitis	Altered Intercellular Communication	Prominent histologic features included epithelioid granulomas with lymphoid cuffing, transmural inflammation with lymphoid aggregates, mucosal ulceration, and cryptitis.	11257626
Osteoporotic Fractures	Altered Intercellular Communication	Bone density, an important predictor of osteoporotic fracture risk, is affected by hormonal and environmental factors.	11259341
Communicable Diseases, Primary malignant neoplasm, Inflammation, Cachexia	Altered Intercellular Communication	Many of these biological response modifiers are responsible for various pathological conditions, including inflammation, infection, cachexia, aging, genetic disorders, and cancer.	11259452
Testicular Neoplasms, Orchitis	Altered Intercellular Communication	Of the 18 patients evaluated, 11 were found to have testicular tumors and 7 testicular inflammation.	11259953
Airway structure, Asthma	Altered Intercellular Communication	These findings suggest that exhaled CO concentrations may relate to the severity of asthma and measurements of exhaled CO concentrations may be a useful means of monitoring airway inflammation in asthma.	11260153
Inflammation, Specimen Type - Fistula	Altered Intercellular Communication	Even after embolization, the tissue surrounding a fistula remains very fragile, so the fistula may easily recur as a result of slight injury or inflammation.	11260338
Inflammation, Vasogenic Edema, Cerebral Edema	Altered Intercellular Communication	In this case, we thought Hounsfield Unit (HU) of the brain edema caused by transudate of CSF through the ventricular wall (12.6) was markedly lower than that of so-called vasogenic edema (25.1) due to active inflammation.	11260892
Inflammation, Pain Distress Question	Altered Intercellular Communication	The Tolosa Hunt Syndrome (THS) is a painful granular inflammation of the cerebral vessels followed by pain and disorders of the extrabulbar muscles.	11261766
Airway structure	Altered Intercellular Communication	Because ultrafine particles are efficiently deposited in the respiratory tract and may be important in initiating airway inflammation, we have initiated clinical studies with ultrafine carbon particles in healthy subjects.	11262441
Airway structure, Thrombophilia	Altered Intercellular Communication	For example, airway inflammation may activate endothelium and circulating leukocytes, and induce a systemic acute phase response with transient hypercoagulability; this could explain the epidemiologic linkages between pollutant exposures and cardiovascular events.	11262441
No ocular symptoms, Vitreous inflammatory cells, Uveitis	Altered Intercellular Communication	As for the ocular symptoms, the majority (78.6%) of patients were classified as intermediate uveitis with vitreous inflammation.	11262653
Granulomatous inflammation	Altered Intercellular Communication	There was no indication of a generalized granulomatous inflammation.	11263049
Inflammation, Airway Obstruction	Altered Intercellular Communication	These symptoms continued under a course of high-dose steroids; thus an operation was necessary to relieve the airway obstruction and limit inflammation.	11263468
Inflammation	Altered Intercellular Communication	Great variability in lymph cytokine concentrations, presumably reflecting differences in the intensity of local inflammation, was not reflected in serum cytokine concentrations.	11263768
Inflammation, SLC22A5 gene, FAM126A gene	Altered Intercellular Communication	Among the histological parameters, SCD, active inflammation and complete nodule were statistically significant factors for the cumulative probability of developing HCC.	11268443
Inflammation	Altered Intercellular Communication	Gallbladder inflammation was evident during an eventual investigatory laparoscopy, and cholecystectomy was performed.	11268943
Obstructive chronic pancreatitis, Pain Distress Question, Pancreatitis, Chronic	Altered Intercellular Communication	Chronic obstructive pancreatitis usually manifests with intractable pain and recurrent episodes of chronic pancreatic inflammation.	11268982
Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Steatosis, hepatocyte damage, inflammation and fibrosis were graded from 0 to 3+, in liver biopsies from 15 well documented nonalcoholic steatohepatitis and 5 normal controls.	11269008
Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	This study demonstrates that hepatic stellate cell activation occurs in nonalcoholic steatohepatitis, clearly correlating with portal and lobular inflammation, but not with steatosis, suggesting that the mechanisms implicated in fibrosis in nonalcoholic steatohepatitis are probably related with inflammation.	11269008
Inflammation, Aspergillus fumigatus allergenic extract	Altered Intercellular Communication	Pathologic and microbiological examination demonstrated Aspergillus fumigatus and active inflammation.	11269424
Refractory anemias, Arthritis	Altered Intercellular Communication	Along with synovial joint inflammation, extra-articular involvement is a common feature of RA.	11269535
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Scintigraphic evaluation of synovial inflammation in rheumatoid arthritis with (99m)technetium-labelled human polyclonal immunoglobulin G. The aim of this study was to investigate whether (99m)technetium-labelled polyclonal human immunoglobulin G (99mTc-IgG) scintigraphy reflects synovial inflammation in patients with rheumatoid arthritis (RA).	11269536
Inflammation, Traumatic injury	Altered Intercellular Communication	Predominant local etiologic factors were trauma (12.9%) and inflammation (14%).	11270104
Inflammation	Altered Intercellular Communication	We tested the hypothesis that elevation of CRP, indicating chronic inflammation, and positive serum antibody titres for C. pneumoniae are associated with an increased cardiovascular mortality in patients on chronic peritoneal dialysis.	11274279
Inflammation, Duodenal Ulcer, epithelium regeneration	Altered Intercellular Communication	As expected, among H pylori biopsy-positive patients, those with duodenal ulcer (DU) (n = 34) had significantly more severe chronic and acute inflammation (P <.001) and epithelial degeneration (P =.004) in the gastric antrum than in the gastric corpus.	11274634
Inflammation, Colonization, Peptic Ulcer, epithelium regeneration	Altered Intercellular Communication	Colonization with vacA s1/cagA-positive strains of H pylori was associated with inflammation and epithelial degeneration in gastric mucosa and increased risk for peptic ulcer disease (PUD), whereas colonization with vacA s2m2/cagA-negative strains was associated with mild gastric histopathology and was not associated with any significant risk for PUD.	11274634
Pain Distress Question, Inflammation	Altered Intercellular Communication	We also analyzed whether an association exists between NK-1R mRNA expression and pain and inflammation.	11275376
Pain Distress Question, Pancreatitis, Chronic	Altered Intercellular Communication	Recent theories of pathogenesis of pain in chronic pancreatitis (CP) are neuroimmune interactions of intrapancreatic nerves and inflammatory cells and increase in levels of pain neurotransmitters such as substance P (SP).	11275376
Pain Distress Question, Inflammation, Complex Regional Pain Syndromes	Altered Intercellular Communication	Complex regional pain syndrome (CRPS) is a disabling disease characterized by the classic symptoms and signs of inflammation.	11275382
Unknown (origin) (qualifier value), Inflammation, Urethral Stenosis	Altered Intercellular Communication	The etiology of urethral stricture was inflammation (4 cases), iatrogenic (5 cases) and idiopathic (11 cases).	11275716
Inflammation, Sinusitis	Altered Intercellular Communication	Orbital inflammation secondary to sinus inflammation is a well known entity and has been widely reported.	11278026
Furunculosis, Orbital Pseudotumor	Altered Intercellular Communication	However, nasal furunculosis resulting in orbital inflammation is a rare occurrence.	11278026
Intestinal metaplasia, Inflammation, Helicobacter pylori	Altered Intercellular Communication	Sections were stained with a triple stain and evaluated for Helicobacter pylori (H. pylori), active inflammation, and intestinal metaplasia.	11280531
Inflammation, Hepatitis C	Altered Intercellular Communication	The present results have shown that the anti-HMA was tightly associated with the degree of hepatocyte inflammation and that the measurement of anti-HMA may have some advantage in clinical evaluation of some of non-B, non-C hepatitis patients.	11280563
Inflammation, Liver damage, Primary Biliary Cholangitis	Altered Intercellular Communication	Highly enhanced nitric oxide production in primary biliary cirrhosis could be related to the development of strong inflammation and at least partially to neutrophil activation, thus suggesting a putative role of these cellular mediators in the development of liver damage owing to their ability to synthesize and release a wide variety of important factors, including elastase and nitric oxide.	11280567
Inflammation	Altered Intercellular Communication	The block biopsy specimens obtained from the cervical lesion revealed fibrotic thickness and chronic inflammation of subcutaneous septa, fascia, and perimysium.	11280899
Inflammation, Arthritis, Osteopenia	Altered Intercellular Communication	In experimental arthritis, blocking of the receptor activator of nuclear factor kappaB ligand (RANKL) by osteoprotegerin (OPG) treatment prevents bone loss but not inflammation, suggesting that there are inflammation-related factors that regulate RANKL and OPG.	11281165
Osteopenia	Altered Intercellular Communication	However, it is not known which factors regulate RANKL and OPG in human inflammation-induced bone loss.	11281165
Refractory anemias, Rheumatoid Arthritis, Periarticular osteoporosis, Degenerative polyarthritis	Altered Intercellular Communication	To clarify the inflammation-related factors that play a role in periarticular osteoporosis in patients with rheumatoid arthritis (RA), the synovial fluid and synovium of the knee joint, and the periarticular cancellous bone of the femoral condyle were collected at surgery from postmenopausal women with RA or osteoarthritis (OA).	11281165
Refractory anemias, Degenerative polyarthritis	Altered Intercellular Communication	Inflammation of the knee joints in patients with RA was confirmed by significantly higher proinflammatory cytokine levels in the synovial fluid and the synovium than those seen in patients with OA.	11281165
Osteopenia	Altered Intercellular Communication	IL-6 and PGE2 released from osteoblast-lineage cells could be, at least in part, responsible for human inflammation-induced bone loss.	11281165
Communicable Diseases, Lacrimal gland cyst, Traumatic injury, Inflammation	Altered Intercellular Communication	Typically, lacrimal gland ductal cysts develop after chronic inflammation, infection, or trauma.	11281587
Carcinoid Tumor, Orbital Pseudotumor	Altered Intercellular Communication	Recurrent orbital inflammation from metastatic orbital carcinoid tumor.	11281589
Orbital Pseudotumor	Altered Intercellular Communication	Both patients sought treatment for acute unilateral orbital inflammation.	11281589
Carcinoid Tumor	Altered Intercellular Communication	Carcinoid tumor metastatic to the orbit may manifest as recurrent orbital and ocular adnexal inflammation.	11281589
Inflammation	Altered Intercellular Communication	At the 6-week assessment, there was a higher level of residual wound inflammation in the polyglactin 910 (Vicryl) group.	11281671
ARCN1 gene, Airway structure, Chronic Obstructive Airway Disease, Asthma, Cystic Fibrosis	Altered Intercellular Communication	Because NO generation is increased in airway inflammation, we have measured RS-NOs in exhaled breath condensate in patients with asthma, cystic fibrosis, or chronic obstructive pulmonary disease (COPD).	11282756
Inflammation, Cardiovascular Diseases, Urinary tract infection, diabetic	Altered Intercellular Communication	These results, apparently in disagreement with earlier reports on the clustering of cardiovascular disease risk factors in hyperinsulinemic individuals, could be due to the high frequency of chronic inflammation and the high prevalence of urinary infections in older diabetic women.	11283197
Communicable Diseases, Inflammation	Altered Intercellular Communication	Chronic subclinical infection or inflammation may account for this association.	11283380
Inflammation, Complication Aspects	Altered Intercellular Communication	In the present article, the different forms of ocular complications in relationship to chronic intestinal inflammations and their possible causes are discussed.	11283786
Granulomatous inflammation	Altered Intercellular Communication	GAP must be histopathologically distinguished from granulomatous inflammation in the breast of autoimmune or infectious origin as specific medical therapy may be available for these latter diseases.	11284310
Inflammation, Synovitis	Altered Intercellular Communication	Clinical joint inflammation in the hands was assessed every 3 months and cumulative synovitis score over the period of study was then calculated for each joint.	11285377
Sclerosis, Inflammation, Malignant Atrophic Papulosis	Altered Intercellular Communication	Histologically, the degree of inflammation was generally sparse and the overall picture mirrored the classic histologic description of Degos' disease with a central roughly wedge-shaped zone of sclerosis surmounted by an atrophic epidermis and hyperkeratotic compact stratum corneum.	11285406
Histiocytosis, Inflammation, Hyperplasia, Neoplasms	Altered Intercellular Communication	So-called "nodular histiocytic hyperplasia" (NHH) is a benign histiocytic lesion caused by mechanical irritation, inflammation, and tumor.	11285623
Inflammation	Altered Intercellular Communication	However, abnormal shadows on chest radiography remain unchanged even when acute symptoms have disappeared, suggesting latent lesional inflammation or recurrence.	11287839
Airway structure	Altered Intercellular Communication	Association of reactive nitrogen species metabolites, myeloperoxidase, and airway inflammation in lung transplants.	11288757
Airway structure	Altered Intercellular Communication	Univariate analysis of airway inflammation in patients showed that it was associated with BALF neutrophils, deltaFEV1, and serum total nitrite.	11288757
Airway structure	Altered Intercellular Communication	Serum nitrite appears to reflect the degree of airway inflammation in this lung-transplant study group.	11288757
Inflammation, Lymphoma, Malignant Neoplasms, Tuberculosis	Altered Intercellular Communication	Overall etiologies comprised malignancy 53.1%, tuberculosis 36.7%, lymphoma 2.0% and chronic nonspecific inflammation 8.2%.	11289011
Inflammation, Nasal Polyps, Respiratory allergy	Altered Intercellular Communication	A clinically slight respiratory allergy, particularly to perennial airborne allergens, might play a relevant role in the pathogenesis of nasal polyposis, probably through the induction of a long-lasting inflammation of the nasal mucosa.	11289325
Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Antigastric autoantibodies in Helicobacter pylori infection: role in gastric mucosal inflammation.	11289707
Intraocular inflammation, Uveitis	Altered Intercellular Communication	Intraocular inflammation intensity was scored on standard uveitis grading system prepared by BenEzra et al.	11291295
Intraocular inflammation, Uveitis	Altered Intercellular Communication	Intraocular inflammation intensity was scored on standard uveitis grading system prepared by BenEzra et al.	11291296
Inflammation, Uveitis	Altered Intercellular Communication	To analyse the etiology, localisation of inflammation, frequency of recurrences and the visual function in the course of uveitis in children.	11291297
Refractory anemias, Inflammation	Altered Intercellular Communication	RA patients treated for five years with MTX showed statistically significant clinical improvement and decrease of inflammation parameters.	11291608
Congestive heart failure	Altered Intercellular Communication	The ability of long-term HRV parameters to better reflect activation of diverse hormonal systems may explain their greater prognostic power for risk stratification in patients with CHF.	11291801
Airway structure, Asthma, Bronchiectasis, Aspergillosis, Allergic Bronchopulmonary	Altered Intercellular Communication	The aim of the present study was to characterize airway inflammation in patients with clinically stable ABPA and asthma, and to correlate this with bronchiectasis severity.	11292112
Inflammatory abnormality of the eye	Altered Intercellular Communication	A descriptive study of 13 patients presenting with idiopathic ocular inflammation involving anterior and posterior segment was performed.	11292408
Inflammation, Tumor Cell Invasion	Altered Intercellular Communication	Viral invasion and inflammation of the motor neurons of the anterior horn cells by the varicella-zoster virus (VVZ) causes clinical weakness at the same time and site as the cutaneous eruption.	11293092
Inflammation, Atrophic	Altered Intercellular Communication	The significant changes (p < 0.05) in the contralateral tubes of patients with FTCA were luminal dilatation (p = 0.0004), plical atrophy (p = 0.0015), and chronic inflammation (p = 0.0089).	11293157
Rosacea, Inflammatory abnormality of the eye	Altered Intercellular Communication	After observing the father's erythematous facial lesions, we attributed the child's ocular inflammation to rosacea (as a forme fruste manifestation) and treated her with systemic erythromycin.	11294589
Peripheral Vascular Diseases, Inflammation, Atherosclerosis	Altered Intercellular Communication	Serum vitamin C concentration is low in peripheral arterial disease and is associated with inflammation and severity of atherosclerosis.	11294804
Peripheral Vascular Diseases, Inflammation, atherosclerotic	Altered Intercellular Communication	Peripheral arterial disease (PAD) is a severe atherosclerotic condition frequently accompanied by inflammation and oxidative stress.	11294804
Inflammation, Asthma	Altered Intercellular Communication	Because an airway-like inflammation has been reported in the gut of asthmatic patients, we sought to examine the expression of immunoregulatory cytokines like IL-4, IL-10, and IL-13 by gut mucosa.	11295668
Inflammation, Aortic Aneurysm	Altered Intercellular Communication	Detection of inflammation in aortic aneurysms with indium 111-oxine--labeled leukocyte imaging.	11295694
Inflammation, Aortic Aneurysm	Altered Intercellular Communication	In this study we investigated the role of scintigraphy in the evaluation of inflammation in aortic aneurysms.	11295694
Inflammation	Altered Intercellular Communication	Excess body weight may be associated with a state of chronic low-grade inflammation in children.	11295710
Inflammation, Fibrous	Altered Intercellular Communication	Histologic examination of the globe showed nongranulomatous, acute (neutrophils) and chronic (lymphocytes and histiocytes) inflammation with proliferation of fibrous tissue within the vitreous cavity, uvea, sclera, and contiguous orbital fibroadipose tissue.	11296029
Inflammation, Asthma, Exacerbation	Altered Intercellular Communication	Mild exacerbations and eosinophilic inflammation in patients with stable, well-controlled asthma after 1 year of follow-up.	11296162
Inflammation, Asthma	Altered Intercellular Communication	To determine the time to exacerbation and probability of a mild exacerbation of asthma, and the impact of eosinophilic inflammation on these parameters in patients with stable, well-controlled asthma.	11296162
ARCN1 gene	Altered Intercellular Communication	Neutrophilic airway inflammation may underlie the pathogenesis of COPD.	11296168
Airway structure, ARCN1 gene	Altered Intercellular Communication	FENO and IS may be useful markers of airway inflammation in COPD patients.	11296168
Federated States of Micronesia, Gastrointestinal inflammation	Altered Intercellular Communication	No correlation with the extent of intestinal inflammation and the occurrence of FM and CWP was found.	11296964
Orbital Pseudotumor	Altered Intercellular Communication	Chronic idiopathic inflammation of the intestine does not appear to predispose to chronic widespread pain.	11296964
Vasculitis, Takayasu Arteritis, Inflammation, Granulomatous inflammation	Altered Intercellular Communication	Although many of the vasculitides within the classification of the American College of Rheumatology can have a component of granulomatous inflammation with giant cells, two (ie, giant-cell [temporal] arteritis and Takayasu arteritis) are characterized by infiltrates that are dominated by granulomatous and/or giant-cell-containing inflammation.	11296990
Inflammation, Bladder Squamous Cell Carcinoma	Altered Intercellular Communication	Epidemiological studies indicate that the development of squamous cell carcinoma of the urinary bladder is closely associated with chronic inflammation of the urinary tract, but the underlying mechanism is unknown.	11297248
Cytomegalovirus Infections, Hemorrhage, Inflammation, Immunocompromised Host, Ulceration, CTCAE	Altered Intercellular Communication	CMV infection frequently involves the gastrointestinal tract of immunocompromised patients causing inflammation, ulceration and haemorrhage.	11298108
Gastrointestinal inflammation	Altered Intercellular Communication	An increased expression of activated beta(1) integrins on LPL in intestinal inflammation may abolish their unresponsiveness to antigens and perpetuate the inflammatory process.	11298349
Gastric Intramucosal Adenocarcinoma, Inflammation	Altered Intercellular Communication	Our results suggest that olprinone at 0.2 microg x kg(-1) x min(-1) suppresses gastric intramucosal acidosis and systemic inflammation following CPB.	11300380
Angina Pectoris	Altered Intercellular Communication	Recurrent unstable angina after directional coronary atherectomy is related to the extent of initial coronary plaque inflammation.	11300434
Angina, Unstable	Altered Intercellular Communication	There is a positive association between the extent of initial coronary plaque inflammation and the recurrence of unstable angina during long-term follow-up after DCA.	11300434
Inflammation, Angina, Unstable	Altered Intercellular Communication	These results underline the role of ongoing smoldering plaque inflammation in the recurrence of unstable angina after coronary interventions.	11300434
Inflammation	Altered Intercellular Communication	Synovial inflammation was estimated histologically and by magnetic resonance imaging (MRI).	11300743
Inflammation, Autoimmune Diseases, physiopathological, "Sjogrens Syndrome", Sicca Syndrome	Altered Intercellular Communication	Among patients with sicca symptoms, those with laboratory evidence of inflammation, autoimmunity or exocrine dysfunction should be subjected to a lower lip biopsy for a final diagnosis of primary Sjogren's syndrome.	11301610
Inflammation, Lesion of lung, Malignant Neoplasms	Altered Intercellular Communication	Benign lung lesion with active inflammation could demonstrate high FDG uptake, making it difficult to differentiate from malignancy.	11302341
Inflammation, Angina, Unstable	Altered Intercellular Communication	These findings may suggest the presence of chronic inflammation with involvement of the endothelium in patients with anginal chest pain and normal coronary angiograms.	11303698
Meningitis, Bacterial	Altered Intercellular Communication	Elevated PCT in bacterial meningitis may indicate the presence of bacterial inflammation outside the central nervous system.	11303813
Inflammation	Altered Intercellular Communication	To investigate the associations between inflammation tests and radiation dose in A-bomb survivors.	11304439
Inflammation	Altered Intercellular Communication	This study suggests statistically significant association between inflammation in A-bomb survivors and radiation dose of during 1988-1992.	11304439
Inflammation, Myocardial Ischemia	Altered Intercellular Communication	C-reactive protein, fibrin D-dimer, and incident ischemic heart disease in the Speedwell study: are inflammation and fibrin turnover linked in pathogenesis?	11304479
Inflammation, Myocardial Ischemia	Altered Intercellular Communication	We conclude that although these respective markers of inflammation and fibrin turnover show modest association with each other in middle-aged men, they may have additive associations with risk of incident IHD.	11304479
Communicable Diseases, Inflammation	Altered Intercellular Communication	IL-10 is implicated in H pylori infection and might "damp down" local inflammation.	11304845
Granulomatous inflammation, Basophilic degeneration	Altered Intercellular Communication	[figure: see text] Four cases of amyloid were identified; in addition, one case of granulomatous inflammation and one case of basophilic degeneration were seen, although all these had been evident on light microscopy.	11304852
Inflammation, Hypothermia due to exposure, Necrosis	Altered Intercellular Communication	We propose that isotonic saline, topical DMSO and local hypothermia may have restricted the inflammation and tissue necrosis induced by the extravasation of docetaxel.	11305072
Inflammation, Colonization	Altered Intercellular Communication	AgNOR indices were not significantly related to grades of H. pylori colonization and chronic and active inflammation.	11305489
Constrictive Bronchiolitis	Altered Intercellular Communication	It may be possible that the active form of constrictive bronchiolitis is initiated by attendant lymphocytic inflammation of the airways, which is followed by fibrous obliteration of bronchioles.	11306739
Hormone abnormality, Hypoglycemia	Altered Intercellular Communication	Anamnesis revealed a weight increase during the preceding 3 months, but no apparent episodes of biochemical hypoglycaemia or hormonal abnormalities.	11306891
Asthmatic Airway Remodeling	Altered Intercellular Communication	Exhaled nitric oxide may be a useful indirect marker of asthmatic airway inflammation.	11307112
Inflammation, Tissue injury	Altered Intercellular Communication	Aetiological considerations connected to tissue injury and inflammation are discussed.	11307467
Inflammation	Altered Intercellular Communication	Inflammation induced disturbances in local homeostasis may possibly explain the lateral breakdown of bone.	11307467
Sleep Apnea, Obstructive, Turnera (plant)	Altered Intercellular Communication	Anatomical upper airway abnormalities and hormonal factors, which predispose Turner patients to develop obstructive sleep apnoea syndrome, are discussed.	11307746
Inflammation	Altered Intercellular Communication	The characteristic pathological finding is of submucosal dense fibrotic tissue with evidence of chronic inflammation.	11307904
Inflammation, Disease	Altered Intercellular Communication	One group consisted of patients with knee joint involvement and severe inflammation without progressive destruction; the other group had knee joint involvement with progressive destruction and low disease activity.	11308059
Inflammation	Altered Intercellular Communication	Characteristic differences between groups with inflammation and destruction were more clearly evident from the alpha angle than from the knee angle itself.	11308059
Rheumatoid Arthritis, destruction joint, Inflammation	Altered Intercellular Communication	We observed gait differences between rheumatoid arthritis patients with active inflammatory arthritic knee joint involvement without progressive destruction and those with joint destruction and minimal inflammation.	11308059
Airway structure	Altered Intercellular Communication	Nonsteroidal anti-inflammatory drugs may have limited applications in the modulation of chronic airway inflammation.	11309715
Gingivitis, Tooth Crowding, Hemorrhage, Dental caries, Leukoplakia, Eruptions, Alveolar Bone Loss	Altered Intercellular Communication	The case of a 14-year-old girl is described who presented with several of the characteristic systemic features of this condition, together with the following oral features: hypodontia, diminutive maxillary lateral incisors, delayed dental eruption, crowding in the maxillary premolar region, short roots, poor oral hygiene, gingival inflammation and bleeding, alveolar bone loss, caries and a smooth atrophic tongue with leukoplakia.	11310247
Inflammation, Neuronal loss in central nervous system	Altered Intercellular Communication	Although PCGs are well-circumscribed lesions, lymphoplasmocytic inflammation, neuronal loss, and reactive gliosis occur within the adjacent cortex.	11310925
Inflammation, Mortality, Premature	Altered Intercellular Communication	A high level of sustained inflammation appears to be an important predictor of premature death.	11312385
Inflammation	Altered Intercellular Communication	Neutrophils also play an important role in inflammatory reactions and the level of myeloperoxidase, a constituent of neutrophil granules, is related to the intensity of the inflammation.	11314241
Arthralgia, Arthritis	Altered Intercellular Communication	Fifty-nine patients with peripheral joint pain were divided into two groups: those with clinical signs of active joint inflammation and those without objective signs.	11314764
Communicable Diseases, Inflammation	Altered Intercellular Communication	No evidence of inflammation or infection was seen in any of these patients.	11314766
Pain Distress Question, Photophobia, Inflammation	Altered Intercellular Communication	Pain and photophobia were abolished in 86% of cases and substantially reduced in 14%, with all eyes exhibiting decreased vascularisation and inflammation at final follow up.	11316719
Chlamydia trachomatis, Urethritis	Altered Intercellular Communication	Men attending a sexually transmitted disease clinic were tested for C trachomatis with ligase chain reaction and culture, and for urethral inflammation with urine leukocyte esterase and urethral Gram stain.	11318253
Urethritis	Altered Intercellular Communication	Ligase chain reaction increased detection by 49% among men without urethral inflammation.	11318253
Urethritis	Altered Intercellular Communication	An age of younger than 25 years and urethral inflammation were associated with positive ligase chain reaction results.	11318253
Urethritis, Infection	Altered Intercellular Communication	An age of younger than 30 years or urethral inflammation identified the highest proportion of infections (92%) and reduced the percentage of men screened by 43%.	11318253
Chlamydia trachomatis, Urethritis	Altered Intercellular Communication	Urine ligase chain reaction increased C trachomatis detection, particularly among men without urethral inflammation.	11318253
Inflammation, Pterygium Of Conjunctiva And Cornea	Altered Intercellular Communication	In pterygium in particular, the biochemical pathway of MT synthesis seems interestingly to cross the pathways of cell proliferation, inflammation and immune activation.	11318304
Inflammation	Altered Intercellular Communication	Plasma esterified F2-isoprostanes may be a useful indicator to evaluate effectiveness of interventions to decrease oxidative stress and associated inflammation.	11318969
Cessation of life, Sepsis, Inflammation, Critical Illness	Altered Intercellular Communication	The majority of problems (death) amongst critically ill patients requiring critical care involve sepsis, inflammation, tissue damage-oxidative stress, oxygen tension PO2, lipid peroxidation.	11319515
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	Antral biopsies were obtained to classify inflammation, activity, atrophy, intestinal metaplasia and H. pylori density grade.	11321891
Inflammation	Altered Intercellular Communication	H. pylori infection was significantly associated with an increased antral inflammation and activity (chi 2 = 21.7, p < 0.001 and chi 2 = 42.0, p < 0.001), and increased mucosal levels of IL-1 beta, IL-8 and TNF alpha.	11321891
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Biopsy specimens were evaluated for the grade of inflammation and stage of fibrosis (scores 0-4).	11322062
Inflammation, Lymphoma, Empyema, Pleural	Altered Intercellular Communication	Pyothorax associated lymphoma (PAL) occurs in a clinical setting of longstanding pyothorax or chronic inflammation of the pleura.	11322168
Inflammation, Percutaneous transhepatic cholangiography, Sudden Visual Loss, Central Nervous System Infection	Altered Intercellular Communication	We describe a 13-month-old infant dependent on peritoneal dialysis, without evidence of central nervous system infection or inflammation, who developed acute vision loss secondary to PTC.	11322367
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Furthermore, the data suggest that chronic inflammation is associated with high levels of methylation, perhaps as a result of increased cell turnover, and that UC can be viewed as resulting in premature aging of colorectal epithelial cells.	11325821
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	C-Reactive protein (CRP) is a strong predictor of clinical outcome in coronary artery disease (CAD), and inflammation has been implicated in the process.	11325892
Craniocerebral Trauma, Inflammation, Thrombosis, Neoplasms, Sinus Thrombosis, Intracranial	Altered Intercellular Communication	Sinus thrombosis has rarely been associated with closed head injury; more often, thrombosis of the sigmoid or transverse sinus is caused by otogenic inflammations or tumours, or occurs during pregnancy.	11326560
Inflammation, Pancreatitis, Malignant Neoplasms	Altered Intercellular Communication	Imaging techniques may fail to differentiate malignant tumors from inflammation, especially in chronic pancreatitis.	11326646
Inflammation	Altered Intercellular Communication	There were expression of hsp70, 90 alpha, 90 beta gene in PMBC from SR asthmatics, but increased with worsening of inflammation and prolonging of the duration of disease.	11326954
Inflammation, Calcinosis	Altered Intercellular Communication	Thirty-six specimens from 34 patients who had acute inflammation and roentgenographically recognized calcification in soft tissue were analyzed.	11327256
Inflammation	Altered Intercellular Communication	The results underline the central role of mast cells in the inflammation of acquired chronic urticaria-angioedema.	11327402
Pain Distress Question, Inflammation, Diarrhea, Ulcerative Colitis	Altered Intercellular Communication	Nicotine decreases diarrhoea and pain in ulcerative colitis without reducing inflammation.	11328259
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histological changes were mild, with low scores for both inflammation and fibrosis, in spite of long exposure to blood products (mean 27 years).	11328286
Inflammation, Positive for tumor protein p53	Altered Intercellular Communication	We investigated the prevalence of p53-positive cells in the gastric mucosa before and one month after eradication of H. pylori and the relationship between p53 positivity and inflammation and cell proliferation.	11328363
Epithelial Damage, Communicable Diseases, Gastritis	Altered Intercellular Communication	Infection with cagA+ H. pylori has greater degree of gastric inflammation and epithelial cell damage.	11328364
Communicable Diseases, Inflammation	Altered Intercellular Communication	Although procalcitonin (PCT) has been described as a new marker of infection and inflammation, it has not been extensively studied in dialysis patients.	11328904
Inflammation, Dysplasia, Colorectal Carcinoma, Colitis	Altered Intercellular Communication	Dysplasia was only found in patients with long-standing colitis or with colorectal cancer and was significantly more often diagnosed in the case of concomitant inflammation.	11330427
Celiac Disease, Inflammation, Villous atrophy	Altered Intercellular Communication	We therefore searched for evidence of disease in 10 adults suspected to have celiac disease, but evincing only minor mucosal inflammation and increase in gammadelta+ cells without villous atrophy.	11330428
Pouchitis	Altered Intercellular Communication	Inflammation of the ileoanal pouch (pouchitis) is one of the main complications after restorative proctocolectomy, yet its cause remains poorly understood.	11330575
Airway structure, Asthma, Asthma attack	Altered Intercellular Communication	This study investigated the relation between asthma attacks and levels of plasma fibronectin (FN) and serum eosinophilic cationic protein (ECP) in patients with bronchial asthma in order to clarify the role of FN in the airway inflammation of bronchial asthma.	11332204
Airway structure	Altered Intercellular Communication	These observations clearly indicate that the decrease in plasma FN associated with attacks is closely related to aggravation of airway inflammation, and that the increase in plasma FN in the non-attack stage reflects chronic airway inflammation.	11332204
Asthma, allergic inflammation	Altered Intercellular Communication	These results suggest that the fluctuation in plasma levels of FN may be one of the factors affecting allergic inflammation and attacks in bronchial asthma.	11332204
Keratitis	Altered Intercellular Communication	The recurrence of lesions only in the peripheral untreated cornea suggests that the inflammatory signal in Thygeson's keratitis may reside in the superficial corneal stroma.	11333334
Inflammation, Hyperemia	Altered Intercellular Communication	Since early platelet accumulation may reflect hyperemia in inflammation, this diagnosis was verified by anti-granulocyte antibody scintigraphy.	11333822
Inflammation	Altered Intercellular Communication	These data show an intense early accumulation of 111In-oxine-labeled-platelets in unspecific inflammation of an AVF.	11333822
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	This observational study in cystic fibrosis children suggests that while inflammation is detected in both lungs, bacterial distribution may be more inhomogeneous.	11334132
Inflammation	Altered Intercellular Communication	Histopathological examinations showed mild acute inflammation in specimens resected 1 day after embolization.	11334300
Stomach Diseases, Inflammation, Helicobacter pylori, Neoplasms, Intestinal metaplasia, Atrophic	Altered Intercellular Communication	Morphologic features studied were macroscopic findings, tumor type, extent of inflammation, atrophy, intestinal metaplasia, reactive gastropathy, and presence of Helicobacter pylori.	11335898
Inflammation, Leprosy	Altered Intercellular Communication	Both diagnosis and classification of leprosy were possible in 40 of these 61 cases; the rest of the aspirates showed nonspecific chronic inflammation.	11335960
Adenocarcinoma, Adenoma	Altered Intercellular Communication	Cases diagnosed cytologically as "atypical" or "adenomatous" showed adenocarcinoma, adenoma, and inflammatory conditions upon biopsy.	11335971
Ischemia, Inflammation, Traumatic injury, Palsy	Altered Intercellular Communication	The common causes of palsy were ischemia, trauma and inflammation.	11336074
Chylous Ascites, CTCAE, Dysplasia, Inflammation	Altered Intercellular Communication	Laparoscopy at age 25 years revealed chylous ascites with marked chronic peritoneal inflammation, and lymphatic dysplasia with lymphocysts.	11336770
Chronic inflammation	Altered Intercellular Communication	PAH is also seen often to be closely associated with chronic inflammation.	11337374
Weight Gain	Altered Intercellular Communication	Further exploration of the neurotransmitters implicated in the antipsychotic-induced BWC is important in order to reduce the morbidity and noncompliance associated with weight gain.	11337942
Inflammation, Wheezing	Altered Intercellular Communication	Although studies examining the serum suggest a role for eosinophils in wheezing episodes in infants and toddlers, the presence of a chronic eosinophilic inflammation within their airways remains to be demonstrated.	11338288
Inflammation, Gingival Hyperplasia	Altered Intercellular Communication	Periodontal examination showed generalized diffuse gingival inflammation and gingival enlargement localized mainly to the anterior region.	11338310
Inflammation, Fibrosis Assessment, Fatty Liver Disease	Altered Intercellular Communication	UB correlated positively and significantly with the diagnosis and grade of NASH, presence of MH, cell swelling, lobular inflammation, and fibrosis.	11338474
Bacterial Endocarditis	Altered Intercellular Communication	Compared with other cases of infective endocarditis, cases of Bartonella endocarditis are more fibrotic and calcified, less vascularized, with less extensive vegetation and chronic inflammation.	11338477
Inflammation, Cholesteatoma, Neoplasms	Altered Intercellular Communication	These incidental findings, which were unrelated to the presenting clinical manifestations, included asymmetric fatty bone marrow (n = 41), inflammation (19), cholesterol granulomas (14), cholesteatomas (9), and neoplasms (5).	11338643
Inflammation, Acute Disease	Altered Intercellular Communication	Most frequently inflammation occurs, which in lot of cases leads to acute abdominal disease.	11339095
Inflammation	Altered Intercellular Communication	Pretreatment degrees of lymphocytes and plasma cells (inflammation) and polymorphonuclear neutrophils (activity) were greater in H. pylori-positive subjects compared with H. pylori-negative subjects (P<0.001), whereas the degree of inflammation decreased (P<0.001), and neutrophils had completely disappeared at 6 months after eradication.	11339417
Inflammation, Acute inflammation, Atrophic	Altered Intercellular Communication	The antrum histological scores for chronic inflammation, acute inflammation, gland atrophy and lymphoid follicles were higher in H. pylori-positive NUD patients than in H. pylori-negative NUD patients (2.09 vs 1.01, P<0.001; 1.22 vs 0.36, P<0.001; 0.76 vs 0.36, P<0.01; 0.33 vs 0.13, P<0.01, respectively).	11339418
Inflammation, Helicobacter pylori Positive, Atrophic	Altered Intercellular Communication	The present study discovered marked differences in age, serum pepsinogen I levels, histological grades of acute inflammation, chronic inflammation, gland atrophy and lymphoid tissue formation between H. pylori-positive and H. pylori-negative NUD patients.	11339418
Progressive neurologic deterioration, Acute lacunar infarction	Altered Intercellular Communication	Neurological deterioration in acute lacunar infarctions: the role of excitatory and inhibitory neurotransmitters.	11340225
Inflammation, Leukopenia	Altered Intercellular Communication	These findings are suggestive of a chronic inflammation in NI-CINA patients which provides the antigenic stimulus for ANA production, and they further support our previously reported suggestion for the possible involvement of such a low-grade chronic inflammatory process in the pathogenesis of neutropenia in the affected subjects.	11340248
Cataract, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Postoperative inflammation after cataract surgery in patients with rheumatoid arthritis.	11340386
Refractory anemias, Inflammation	Altered Intercellular Communication	We found no correlation between the extent of anterior chamber inflammation and the preoperative activity of RA.	11340386
Refractory anemias, Inflammation	Altered Intercellular Communication	Postoperative anterior chamber inflammation was also not associated with the medical management of RA.	11340386
Sinusitis	Altered Intercellular Communication	The results suggest that US is a relatively sensitive method also in the diagnosis of prolonged maxillary sinus inflammations.	11340694
Inflammation, Blood Vessel	Altered Intercellular Communication	Inflammation produces reactive oxygen intermediates (ROI) that cause vascular damage and activate T lymphocytes.	11341102
Malignant melanoma of choroid, Orbital Pseudotumor	Altered Intercellular Communication	Orbital inflammation in a patient with extrascleral spread of choroidal malignant melanoma.	11341456
Fever, CTCAE, Total ophthalmoplegia, Blindness, Zygomycosis, Orbital Pseudotumor, Dehydration, Inflammatory disorder	Altered Intercellular Communication	An elderly woman presented with fever, dehydration, orbital inflammation, total external and internal ophthalmoplegia and blindness, resembling the clinical appearance at presentation of severe orbital inflammatory disease or mucormycosis.	11341456
Uveal melanoma, Orbital Pseudotumor, Necrosis	Altered Intercellular Communication	As computed tomography scanning may not be able to delineate an entirely necrotic intraocular malignant melanoma, B-scan ultrasonography should be considered in patients with orbital inflammation, especially in the presence of a retrobulbar mass.	11341456
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Abdominal aortic aneurysm is a multifactorial disorder in which inflammation is an important pathophysiological feature.	11342474
Inflammation, Malignant Neoplasms, Urinary tract infection	Altered Intercellular Communication	Urinary tract infection, inflammation and malignancy associated with other genitourinary organs were the primary cause for false-positive test results in the 3 assays evaluated.	11342897
Cystitis, Genitourinary Cancer	Altered Intercellular Communication	Urinary tract inflammation and other genitourinary malignancies might contribute to the reduction in specificity of these tests.	11342897
Inflammation, Sarcoidosis, Edema	Altered Intercellular Communication	Images of the heart obtained by Gd-MRI may reflect active inflammation with interstitial edema in patients with sarcoidosis.	11343665
Inflammation, Hemosiderin deposits	Altered Intercellular Communication	Histological examination revealed chronic inflammation with hemosiderine deposits and giant cells.	11343965
Inflammation, Atheroma	Altered Intercellular Communication	No significant inflammation, foam cells, cholesterol clefts, or other evidence of atheroma were present.	11343995
Diverticulosis, Inflammation, Gastrointestinal Hemorrhage, Neoplasms	Altered Intercellular Communication	The colonoscopy was normal or revealed only diverticulosis or nonspecific inflammation in 8,473 (62.4%), lower gastrointestinal bleeding in 4 (0.03%), polyps in 4,645 (34.2%), and tumors in 458 (3.4%) patients.	11344424
Intraocular inflammation, Uveitis	Altered Intercellular Communication	The intraocular inflammation (uveitis) was classified according to anatomical site of ocular involvement and the most probable etiological factor.	11344713
Intraocular inflammation	Altered Intercellular Communication	Bilateral intraocular inflammation was observed in 70.3% of the cases and 29.7% had either the left or the right eye involved.	11344713
Intraocular inflammation	Altered Intercellular Communication	In children, symptomatology of the intraocular inflammation may be very mild.	11344713
Inflammation, Peritonitis, Pleurisy, Brucellosis, Arthritis	Altered Intercellular Communication	Familial Mediterranean fever is a genetic disorder manifested by recurrent attacks of peritonitis, pleuritis and arthritis, and characterized by clinical, histological and laboratory evidence for localized and systemic inflammation.	11344818
Inflammation, Myocardial Ischemia, Atherosclerosis	Altered Intercellular Communication	Inflammation may play an important role in the initiation and progression of atherosclerosis and ischemic heart disease.	11344818
Inflammation, Familial Mediterranean Fever, Myocardial Ischemia	Altered Intercellular Communication	These findings suggest that despite the evidence of recurrent inflammation, colchicine-treated FMF patients are not more predisposed to IHD than the normal population.	11344818
Inflammation, Doxorubicin/Methotrexate/Vinblastine	Altered Intercellular Communication	The operative specimen showed AVM embolized by HEMA-MMA with non-specific inflammation and partial inflammatory degeneration of the vascular wall.	11344916
Gammopathy, Monoclonal Gammopathy of Undetermined Significance, Idiopathic pneumonia syndrome	Altered Intercellular Communication	This study describes the frequency of monoclonal gammopathy of undetermined significance (MGUS) and the changes in some inflammation-related serum proteins in 157 patients with nonimmune chronic idiopathic neutropenia syndrome (NI-CINS).	11345200
Inflammation, Leukopenia	Altered Intercellular Communication	These findings are consistent with our previous report suggesting the possible existence of an unrecognized low-grade chronic inflammation in patients with NI-CINS, which may be involved in the pathogenesis of neutropenia in the affected subjects.	11345200
Granulomatous inflammation	Altered Intercellular Communication	Histologic examination revealed exuberant nonnecrotizing, frequently bronchiolocentric, granulomatous inflammation in all cases.	11345841
Inflammation, Pneumonia, Interstitial	Altered Intercellular Communication	The inflammation often was associated with patchy chronic interstitial pneumonia and organization.	11345841
Inflammation, Retractile Mesenteritis	Altered Intercellular Communication	Retractile mesenteritis is a rare condition in which the inflammation process of the mesentery is the characteristic pathological.	11347513
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	The histologic changes are variable proportions of fat necrosis, chronic inflammation and fibrosis.	11347513
Communicable Diseases, Inflammation, Failure (biologic function)	Altered Intercellular Communication	Complications were limited to local infection and inflammation at the implant site in three patients, and failure to osseointegrate in one patient.	11347635
Cessation of life, Inflammation, Myocardial Infarction, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Considering that there were regions in the myocardium without the traditional findings of myocardial necrosis and inflammation but with distinct expression of the above mentioned immunohistologic markers, immunohistological investigations turn out to be an appropriate tool to examine infant fatalities with uncertain cause of death for early stages of myocarditis.	11348811
thromboembolic, Bacterial Endocarditis	Altered Intercellular Communication	Inflammation-induced procoagulant changes and endothelial cell activation appear to play an important role in thromboembolic complications of infective endocarditis.	11350097
Inflammation, Chronic heart failure	Altered Intercellular Communication	Physical training reduces peripheral markers of inflammation in patients with chronic heart failure.	11350112
Inflammation, Chronic heart failure	Altered Intercellular Communication	Training-induced improvement in exercise tolerance is correlated with the attenuation of the inflammatory process, indicating that inflammation may contribute significantly to the impaired exercise capacity seen in chronic heart failure.	11350112
Inflammation, Asthma	Altered Intercellular Communication	There were no other associations between markers of asthma severity and inflammation.	11350304
Eosinophilic disorder, Inflammation, Asthma	Altered Intercellular Communication	This study confirms that eosinophilia is the index of inflammation that is most closely related to the clinical severity of childhood asthma.	11350304
Gingivitis, Periodontitis, Chronic granulomatous disease	Altered Intercellular Communication	The purpose of this report is to describe a 5-year old male patient suffering from prepubertal periodontitis associated with chronic granulomatous disease, who was referred to the Department of Periodontology for treatment of severe gingival inflammation.	11350528
Inflammation	Altered Intercellular Communication	After eradication of H. pylori, the incomplete type changed to the complete type with a decrease of histological inflammation.	11350546
Alveolitis, Myositis, CTCAE 5.0, Myositis	Altered Intercellular Communication	Alveolitis may persist during treatment that sufficiently controls muscle inflammation in myositis.	11354558
Inflammation, Peripheral Nervous System	Altered Intercellular Communication	In vitro and in vivo models have implicated numerous cytokines as major modulators of inflammation, destruction and repair in the peripheral nervous system (PNS).	11355311
Chronic inflammation, Telangiectasis	Altered Intercellular Communication	Histological examination of the flaps showed varying degrees of telangiectasia and mild chronic inflammation.	11355983
Inflammation, Mycoses, Telangiectasis	Altered Intercellular Communication	The erythematous clinical appearance was not correlated with the presence of chronic fungal infection, but reflected the presence of vascular repair tissue, telangiectasia and mild residual chronic inflammation.	11355983
Inflammation, Fibrosis Assessment, Calcinosis, ras GTPase-Activating Proteins, Pathologic Neovascularization	Altered Intercellular Communication	Haematoxylin and Eosin and Movat's pentachrome stains were used to assess the degree of intimal thickening, presence or absence of inflammation, type of inflammatory cell(s), the degree of reduplication of elastic lamina, calcification, fibrosis, neovascularisation and gaps or losses in the internal and external elastic lamina.	11358048
Inflammation, Temporal Arteritis	Altered Intercellular Communication	No histological findings were specific for temporal arteritis except the presence of mural inflammation.	11358048
Inflammation, Arteriosclerosis, Temporal Arteritis	Altered Intercellular Communication	These results indicate that, in the absence of active inflammation, structural changes in the vessel wall do not allow reliable differentiation between healed or quiescent temporal arteritis and arteriosclerosis.	11358048
Inflammation, Juvenile Xanthogranuloma	Altered Intercellular Communication	Our case findings suggest that xanthomatization of the JXG could have been accelerated by the inflammation associated with the biopsy, based on the histopathologic fact that the change from an early phase to a mature form occurred within the very short period of 2 weeks.	11358553
Inflammation, Failure (biologic function)	Altered Intercellular Communication	All failures occurred in fresh extraction sites, and extra care is recommended to avoid situations with ongoing inflammation in these situations.	11359258
Fibrous, Inflammation	Altered Intercellular Communication	Deep peri-implant tissues surrounding mobile implants consisted of a dense, fibrous tissue capsule with minimal inflammation.	11359271
Airway structure, Asthma	Altered Intercellular Communication	Serum eosinophil cationic protein (ECP) levels reflect ongoing eosinophilic airway inflammation and are used as a marker for asthma activity.	11359433
Inflammation, Asthma	Altered Intercellular Communication	Mechanisms other than eosinophilic inflammation, such as airway remodelling, may be involved in asthma exacerbation in these patients.	11359433
Neurogenic Inflammation	Altered Intercellular Communication	These results suggest that substance P induces the release of LTB4 in a certain population of human individuals by a glucocorticosteroid-dependent mechanism, and plays an important role in neurogenic inflammation with granulocyte infiltration.	11359454
Inflammatory abnormality of the eye, Eye Manifestations, Physiologic Intraocular Pressure	Altered Intercellular Communication	We describe a series of patients with ocular manifestations of WG to evaluate the presence of ocular lesions in the setting of systemic WG and to determine the value of ocular inflammation in the diagnosis of WG.	11361183
Inflammatory abnormality of the eye	Altered Intercellular Communication	Group II included 3 patients (6.3%) who had ocular inflammation first and who then subsequently developed systemic manifestations of WG.	11361183
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation can occur with or without obvious systemic manifestations of WG.	11361183
Nephritis, Interstitial, Inflammation	Altered Intercellular Communication	Renal biopsy showed interstitial nephritis and chronic inflammation.	11362124
Inflammation, Dental Plaque	Altered Intercellular Communication	Three hundred sixteen subjects with mild-to-moderate gingival inflammation and plaque received a dental prophylaxis and began their randomly assigned brushing and rinsing regimen in an unsupervised setting.	11367972
Inflammation, Helicobacter pylori, Coronary heart disease	Altered Intercellular Communication	Helicobacter pylori heat shock protein 60 and risk of coronary heart disease: a case control study with focus on markers of systemic inflammation and lipids.	11369014
Inflammation, Helicobacter pylori, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	We conducted a case-control study to investigate whether antibodies against Helicobacter pylori heat shock protein 60 (hsp60) are associated with CHD, and focused specifically on markers of systemic inflammation and lipids.	11369014
Inflammation, Cholestasis	Altered Intercellular Communication	Persistent inflammation and immune activation contribute to cholestasis in patients receiving home parenteral nutrition.	11369168
Inflammation	Altered Intercellular Communication	Ongoing inflammation was implicated in HPN-associated cholestasis, so we examined the relation between liver-enzyme concentrations and circulating inflammatory and immune markers in these patients.	11369168
Inflammation, Toxic effect	Altered Intercellular Communication	Our results confirmed that the number of infused calories contributes to liver toxicity in HPN patients and strongly suggested that sustained inflammation is probably a key factor in worsening HPN-associated cholestasis.	11369168
Retinal Detachment, Inflammation, Necrosis	Altered Intercellular Communication	We propose that inflammation of the sclera in close contact with necrotic fungi materials may cause serous retinal detachment.	11369382
Inflammation, Hemorrhage, Non-necrotizing granulomatous inflammation, Ulcer, Crohn Disease	Altered Intercellular Communication	The bleeding source was several ulcers in an inflamed ileum and histopathologic examination revealed typical findings of Crohn's disease with a chronic, transmural inflammation, non-caseating granuloma and the Ziehl-Neelsen stain was negative.	11369966
Inflammation	Altered Intercellular Communication	Light microscopy of liver biopsy specimens obtained at ages 2, 5, and 7 years showed slight hepatocyte disarray and minimal mononuclear-leukocyte lobular inflammation, with eosinophilic inclusion bodies in the cytoplasm of hepatocytes throughout the lobule.	11370269
Inflammation	Altered Intercellular Communication	In addition, we compared the reproducibility of markers of inflammation in induced sputum with the reproducibility of the FEV(1) and the methacholine PC(20).	11371420
Airway structure, Inflammation	Altered Intercellular Communication	Importantly, we demonstrate that measurement of markers of inflammation in induced sputum is as reproducible as methacholine PC(20) and should prove useful in the assessment of airway inflammation in multicenter clinical trials.	11371420
Inflammation	Altered Intercellular Communication	The inducible form of cyclooxygenase (i.e., COX-2) is activated by the transcription factor nuclear factor (NF)-kappaB and is thought to play a role in inflammation.	11371742
Sinusitis, Atopy	Altered Intercellular Communication	Immunopathologic study of chronic sinusitis: a proposal for atopic and non-atopic IgE-activated mast cell allergic inflammation.	11372929
Respiratory Distress Syndrome, Adult, Inflammation, Hemoptysis, Hypoxemia, Pneumonitis	Altered Intercellular Communication	PATIENTS AND PROCEDURE: BMS was applied in a control group of seven patients who had hemoptysis or small solitary peripheral nodules but no hypoxemia or other signs of acute inflammation and in four patients with acute respiratory distress syndrome (ARDS), to test whether BMS can ascertain the presence of acute pulmonary inflammation without complications.	11373491
Respiratory Distress Syndrome, Adult	Altered Intercellular Communication	Serial BMS was safely performed in one patient with ARDS, allowing us to observe a correlation between changes in the concentration of inflammation-related biochemical markers and clinical course of the disease.	11373491
Granulomatous inflammation	Altered Intercellular Communication	This may be due to the heterogeneous nature of CD where only about 50% of the patients show granulomatous inflammation.	11374694
Inflammation, Hepatolenticular Degeneration, Neoplasms, Cardiovascular Diseases, Dermatologic disorders, Diabetes Mellitus, Anemia	Altered Intercellular Communication	There was an increase in catalase activity in all studied patients suffering from oxidative stress (cardiovascular diseases, diabetes, tumor, inflammation, dermatological diseases, anemia and Wilson's disease).	11376358
Communicable Diseases	Altered Intercellular Communication	In this paper, a polymorphism of another inflammation-related enzyme, myeloperoxidase (MPO), was examined with respect to association with the HP infection.	11376556
Carotid Stenosis, Sinusitis	Altered Intercellular Communication	A 10-year-old male with painful ophthalmoplegia and a cavernous sinus inflammation associated with an intracavernous carotid stenosis demonstrated by magnetic resonance imaging and angiography is reported.	11377111
Tolosa-Hunt Syndrome, Sinusitis	Altered Intercellular Communication	This report suggests that in the presence of painful ophthalmoplegia, magnetic resonance imaging detection of cavernous sinus inflammation can facilitate the diagnosis of Tolosa-Hunt syndrome when other causes are excluded.	11377111
Inflammation, MS gene	Altered Intercellular Communication	Postoperative inflammation in a patient with multiple sclerosis.	11377914
Pain Distress Question, Inflammation	Altered Intercellular Communication	Topical corticosteroids relieved the pain and inflammation within hours.	11377914
Communicable Diseases, Inflammation, MS gene	Altered Intercellular Communication	Acute inflammation in MS patients during the postoperative period may be noninfectious and could be a prodrome for a relapse of MS.	11377914
Inflammation, Data types - Address	Altered Intercellular Communication	Taken together our results seem to suggest that inflammation is a relevant factor in AD pathogenesis for subjects with E3-E3 and E3-E2 genotypes but less important for APOE*4 carrying subjects.	11378247
Communicable Diseases, Inflammation, Cirrhotic, Peritonitis	Altered Intercellular Communication	The clinical features of peritonitis are usually absent in cirrhotic patients with an ascitic fluid infection, raising the interest for specific biological markers of inflammation.	11379342
Epithelial Damage, Inflammation	Altered Intercellular Communication	Our results also indicate that epithelial damage may be affected by mechanisms independent of H. pylori density or inflammation.	11380321
Epithelial Damage, Inflammation	Altered Intercellular Communication	More research is needed to investigate mechanisms leading to epithelial damage which are independent of H. pylori density and inflammation.	11380321
Granulomatous inflammation, Giant Cells, Langhans, Caseous necrosis	Altered Intercellular Communication	On histological examination, caseous necrosis and granulomatous inflammation with Langhan's giant cells were seen in 71% and 40% of patients, respectively.	11380494
Colitis	Altered Intercellular Communication	Collagenous and lymphocytic colitis are two inflammatory conditions of the colon that are often collectively referred to as microscopic colitis.	11381303
Inflammation, Specimen Type - Fistula	Altered Intercellular Communication	This procedure can produce good results when a fistula is too large to allow safe embolization and when excision would be hazardous due to inflammation surrounding the fistula.	11381517
Inflammation, Reperfusion Injury, Ischemia	Altered Intercellular Communication	Interleukin-8 (IL-8), soluble E-selectin (sE-selectin) and polymorphonuclear (PMN-) elastase were measured as markers of systemic inflammation following whole body ischaemia and reperfusion injury.	11382526
Pituitary Adenoma	Altered Intercellular Communication	These results suggest that inhibins and activins may play a role in the local regulation of pituitary hormonal secretion both in normal adenohypophysial cells and in pituitary adenomas.	11383477
Inflammation, Ulcer	Altered Intercellular Communication	The most common histological findings were active chronic inflammation (75%) and ulcer (30%).	11383583
Inflammation, Traumatic injury	Altered Intercellular Communication	Inflammation plays a pivotal role in the pathogenesis of organ injury after cardiopulmonary bypass (CPB).	11383794
Acute postoperative endophthalmitis, Inflammation, Reduced visual acuity, Vitreous strands	Altered Intercellular Communication	The inflammation was located primarily in the posterior one third of the vitreous, and except for severely impaired visual acuity, the classic signs of acute postoperative endophthalmitis were not present until the next day.	11384583
Inflammation, Endophthalmitis, CTCAE	Altered Intercellular Communication	Acute postoperative bacterial endophthalmitis may present with atypical clinical signs and inflammation located primarily in the retina and posterior vitreous.	11384583
Inflammation, Pain Distress Question	Altered Intercellular Communication	Treatment was well tolerated, but more uhCG patients reported local reactions (particularly inflammation and pain) (P=.0001; logistic regression).	11384635
Inflammation, Obstruction, Cholangiocarcinoma	Altered Intercellular Communication	Chronic inflammation and obstruction may predispose the patient to cholangiocarcinoma.	11387004
Inflammation, Crypt hyperplasia, Villous atrophy	Altered Intercellular Communication	Endoscopic duodenal biopsy showed intense chronic inflammation without villous atrophy or crypt hyperplasia.	11388596
Mesenteric Panniculitis, Inflammation	Altered Intercellular Communication	Mesenteric panniculitis is a rare disease characterized by nonspecific inflammation of the fat tissue of the mesentery.	11391153
Alzheimers Disease", Senile dementia	Altered Intercellular Communication	Autoantibodies to beta-amyloid and neurotransmitters in patients with Alzheimer's disease and senile dementia of the Alzheimer type.	11391392
Granulomatous inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	One patient who was diagnosed with granulomatous inflammation on FNA was found to have nonsmall cell lung carcinoma on subsequent transbronchial biopsy.	11391606
Granulomatous inflammation, Pseudotumor, Neoplasms, Fibrous Tissue, Pneumonia	Altered Intercellular Communication	The FNA from the organizing pneumonia was interpreted as a solitary fibrous tumor whereas the inflammatory pseudotumor was diagnosed as granulomatous inflammation.	11391606
Cataract, Acute inflammation, Traumatic injury	Altered Intercellular Communication	The early postoperative inflammation after cataract surgery is mainly caused by surgical trauma.	11392263
Acute inflammation	Altered Intercellular Communication	The early postoperative inflammation is influenced by the duration of phacoemulsification.	11392263
Acute inflammation	Altered Intercellular Communication	Surgical techniques and phacomachines that may reduce phacotime are helpful with respect to early postoperative inflammation.	11392263
Inflammation	Altered Intercellular Communication	We conclude that 'healthy' smoking men with a near normal FEV1 show signs of inflammation in the lower airways that are related to a decrease in DL(CO) and to emphysematous lesions on HRCT.	11392577
Cataract, Inflammation, Uveitis	Altered Intercellular Communication	Uveitis was monocular, the etiology unknown and clinically significant cataract was diagnosed after several months from the beginning of inflammation.	11392800
Inflammation, Anterior uveitis	Altered Intercellular Communication	Two months after PC-IOL implantation the symptoms of mild inflammation in the eye of 15-year-old boy with anterior uveitis occurred.	11392800
Cataract, Inflammation, Uveitis	Altered Intercellular Communication	Establishing the diagnosis and controlling the inflammation pre- and postoperatively are the basic conditions for the surgical outcomes in cataract surgery in patients with history of uveitis.	11392803
Inflammation, Nervous System Physiological Phenomena, Gout	Altered Intercellular Communication	It was suspected that inappropriate physical therapy might have aggravated acute inflammation of spinal gout and resulted in a rapid deterioration of neurologic function.	11393117
Inflammation, Bacterial Infections, Periodontal Route of Administration	Altered Intercellular Communication	The cytokines and nitric oxide released in periodontal lesions have been reported to play a protective role in bacterial infection and to relate to the process of inflammation.	11394393
Inflammation, Periodontitis	Altered Intercellular Communication	The expression of IL-6 may reflect inflammation in gingival tissue, and iNOS may be involved in the inflammatory process in periodontitis.	11394393
Inflammation, diabetic	Altered Intercellular Communication	We concluded that periodontal inflammation may result in higher levels of GAD and influence GAD antibody titer, and, hence, affect diabetic diagnosis based upon GAD antibody production.	11394394
Inflammation	Altered Intercellular Communication	Persistent inflammation of the gallbladder was seen on computerized tomographic scans and a nonfunction of the gallbladder was demonstrated through radio-nucleotide scanning.	11394434
Inflammation, Infection, Atherosclerosis	Altered Intercellular Communication	Recent data suggest that infections, inflammation and the immune system are involved in the process of atherosclerosis.	11395043
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	In conclusion, CRP, SAA and fibrinogen, which are markers of inflammation, were positively and significantly associated with prevalent CHD.	11395043
Pain Distress Question, Inflammation	Altered Intercellular Communication	The presenting symptom was a scrotal mass, isolated in one case and associated with pain and inflammation in the other case.	11396111
Bardet-Biedl Syndrome, Psychiatric, Craniopharyngioma	Altered Intercellular Communication	Following physical, ophthalmologic, psychiatric, hormonal and radiologic examinations, the diagnosis of both craniopharyngioma and Bardet-Biedl syndrome was established.	11396382
Peritonitis, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	In 24 of the 25 patients who underwent laparoscopy with directed biopsy, whitish nodules suggested tuberculous peritonitis; 76% of the biopsy specimens revealed caseating, 20% non-caseating granulomatous inflammation, and 4% non-specific findings.	11396540
Hormone abnormality, Klinefelter Syndrome	Altered Intercellular Communication	Older age was significantly correlated with increases in VIQ relative to PIQ in the patient group, which suggests the intriguing possibility that the PIQ < VIQ subgroup primarily emerges in young adulthood, perhaps in response to the reported hormonal abnormalities detected in Klinefelter syndrome patients during puberty.	11396547
Inflammation, Septic Shock	Altered Intercellular Communication	Our data suggest that during immune-mediated inflammation (such as septic shock) MIF is an important neuroendocrine mediator: a contraregulator of the immunosuppressive effects of glucocorticoids.	11397892
Inflammation	Altered Intercellular Communication	Vascular endothelial growth factor (VEGF), which is known to be an angiogenetic factor, plays an important role in the inflammation of synovial tissue.	11398859
Inflammation, Bronchopulmonary Dysplasia	Altered Intercellular Communication	Inflammation plays an important role in the pathogenesis of bronchopulmonary dysplasia (BPD), but the exact nature of this inflammatory process is incompletely understood.	11399701
Inflammation, Bronchopulmonary Dysplasia, Lung Injury	Altered Intercellular Communication	Urinary LTE(4) levels may reflect lung injury and/or inflammation in premature infants, not necessarily related to BPD as it is presently defined.	11399701
Inflammation, Cholestasis	Altered Intercellular Communication	During therapy, the most common findings from 40 biopsies (25 patients) were cholestasis (33 biopsies), acute rejection (10), and periportal inflammation (8).	11401179
Bronchitis	Altered Intercellular Communication	Extended exhaled NO measurement differentiates between alveolar and bronchial inflammation.	11401873
Asthma, Bronchitis, Alveolitis	Altered Intercellular Communication	In conclusion, extended exhaled NO measurement can be used to separately assess alveolar and bronchial inflammation and to assess disease activity/severity in asthma and alveolitis.	11401873
Inflammation, Data types - Address	Altered Intercellular Communication	These results support the hypothesis that inflammation is important in the clinical course of AD.	11402127
Dryness of eye, Conjunctivitis	Altered Intercellular Communication	The conjunctival inflammation and reduced goblet cell density of dry eye is exacerbated by use of preserved topical agents, and is not significantly improved by use of non-preserved artificial tear supplements alone.	11402374
Dryness (characteristic), Inflammatory abnormality of the eye	Altered Intercellular Communication	Therapeutic strategies for dry eye should aim to increase goblet cell density and control ocular surface inflammation.	11402374
Erectile dysfunction	Altered Intercellular Communication	The prevalence of erectile dysfunction particularly is common at a period in life when alterations occur in male hormonal environment.	11402581
Cushing Syndrome, parathyroid hormone secretion, Aldosterone-Producing Adrenal Cortex Adenoma	Altered Intercellular Communication	A case of aldosterone-producing adrenocortical adenoma associated with preclinical Cushing's syndrome and hypersecretion of parathyroid hormone.	11403095
Inflammatory, Disturbance, Inflammation, Neuronal degeneration	Altered Intercellular Communication	Previous studies have shown that 57Co single photon emission computed tomography (SPECT) is able to visualize inflammatory lesions, probably by means of the final common pathway of Ca2+ homeostasis disturbance in both neuronal degeneration and inflammation.	11403184
Inflammation	Altered Intercellular Communication	This may contribute to hyporesponsiveness of immune cells in systemic inflammation.	11405088
Inflammation, Carcinoma, Infection, Condylomata Acuminata	Altered Intercellular Communication	Other factors positively associated with invasive carcinoma or CIS or both were injury to the penis, cigarette smoking, physical inactivity and, to a lesser extent, genital warts and other infections or inflammation of the penis.	11405332
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Quantitative ultrasonography in rheumatoid arthritis: evaluation of inflammation by Doppler technique.	11406524
Finger joint structure, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To evaluate ultrasonographic methods, including the Doppler technique, as measures of synovial inflammation in finger joints of patients with rheumatoid arthritis.	11406524
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Ultrasonography may be useful in monitoring the synovial inflammation in rheumatoid arthritis.	11406524
Primary malignant neoplasm, Neoplasm Metastasis, Pancreatic carcinoma, Pancreatitis	Altered Intercellular Communication	Due to the critical function of hpa in cancer cell invasion and metastasis, we have analyzed the expression of hpa in human primary and metastatic pancreatic cancer as well as in the normal pancreas and in chronic pancreatic inflammation.	11406531
Autoimmune Diseases, Inflammation, Fatigue	Altered Intercellular Communication	Even in SS fatigue is only in part explained by clinical disease manifestations and laboratory tests assessing inflammation and autoimmunity.	11407086
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	The results of our study suggest that increased CSF TNF-alpha levels may represent acute intracerebral inflammation in stroke, whereas elevated levels of TNF-alpha in serum may reflect the peripheral proinflammatory state as well as stroke-induced systemic inflammatory reaction.	11407149
Inflammation, Helicobacter pylori, Communicable Diseases, Chlamydia, Coronary Artery Disease	Altered Intercellular Communication	1) There is a significant link between coronary artery disease and infection with Helicobacter pylori, especially expressing CagA proteins, 2) Helicobacter pylori eradication significantly attenuates reduction in coronary artery lumen in coronary artery disease patients after percutaneous coronary angioplasty possibly by elimination of chronic inflammation and decline in proinflammatory cytokine release, and 3) Infection of Chlamydia pneumoniae in these percutaneous coronary angioplasty patients is not affected by eradication therapy.	11407666
Tumor necrosis, Inflammation	Altered Intercellular Communication	The combination of tumor necrosis factor alpha blockade with interleukin-1 and interleukin-17 blockade is more effective for controlling synovial inflammation and bone resorption in an ex vivo model.	11407688
Inflammation, Fibrosis Assessment, Liver Cirrhosis	Altered Intercellular Communication	The persistent activation of these macrophages may lead to the chronic release of TGFbeta and contribute to chronic inflammation, fibrosis and cirrhosis.	11408017
Inflammation, Primary malignant neoplasm, Pulmonary Embolism, Autoimmune Diseases, Cessation of life	Altered Intercellular Communication	The nucleosome is the primary repeating unit of DNA organization in chromatin, and cell death may lead to increased levels of circulating nucleosomes in plasma (PNLs) in various circumstances such as inflammation, pulmonary embolism, autoimmune disease, and cancer.	11408935
Inflammation	Altered Intercellular Communication	Power Doppler sonography (PDS), a newer technique, enables detection of muscle vascularity and inflammation.	11409119
Inflammatory abnormality of the eye, Inflammatory disorder, Arthropathy	Altered Intercellular Communication	Sixteen patients (4 males and 12 females aged 7 to 78 years) who received etanercept (n = 14) or infliximab (n = 2) for either inflammatory eye disease or associated joint disease were studied retrospectively to determine the effect of these medications on their ocular inflammation.	11409666
Inflammatory abnormality of the eye, Acute inflammation, Arthropathy	Altered Intercellular Communication	Although 12 of 12 patients with active articular inflammation (100%) experienced improvement in joint disease, only 6 of 16 with ocular inflammation (38%) experienced improvement in eye disease.	11409666
Inflammation, Joint swelling, Pain Distress Question	Altered Intercellular Communication	High blood levels of uric acid lead to inflammation, joint swelling, and severe pain.	11410763
Degenerative polyarthritis, Inflammation, Abnormal degeneration	Altered Intercellular Communication	Unlike osteoarthritis, it involves primary tissue inflammation rather than joint degeneration.	11410765
Chronicity, Inflammation	Altered Intercellular Communication	In CD LPT, a low Bax expression and a high Bcl-x(L)/Bax ratio favour resistance to apoptosis and may contribute to the chronicity of inflammation.	11413108
Inflammation, Fibrosis Assessment, Fatty degeneration, Reactivation of hepatitis C viral hepatitis	Altered Intercellular Communication	Non-specific alterations of the liver tissues included fatty steatosis (49.6%), fibrosis (55.6%), portal inflammation and reactive hepatitis.	11414408
Inflammation, Subarachnoid Hemorrhage	Altered Intercellular Communication	This was complicated by a subclinical spinal subarachnoid hemorrhage which was related to necrotizing inflammation of small leptomeningeal vessels.	11414480
Infarction, Inflammation	Altered Intercellular Communication	Renal cortical infarcts were due to similar inflammation in arcuate and interlobular arteries.	11414480
Airway structure, Airway Obstruction	Altered Intercellular Communication	We conclude that clarithromycin is not uniformly effective in improving airway obstruction or in decreasing airway inflammation in patients with CF.	11416873
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	While inflammation is considered to be one of the major checkpoints in autoimmune disease progression, very little is known about the initiating events that trigger inflammation.	11418630
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Associations between cancer and inflammation of the muscles.	11419414
Inflammation, Gastritis	Altered Intercellular Communication	NTYR staining was associated with the intensity of inflammation (p = 0.04) and gastritis activity (p = 0.07).	11419826
Congestive heart failure	Altered Intercellular Communication	The syndrome of congestive heart failure (CHF) entails complex autonomic and hormonal responses.	11420763
Congestive heart failure	Altered Intercellular Communication	The ability of long-term HRV parameters to reflect in part the activation of diverse hormonal systems may explain their greater prognostic power for risk stratification in patients with CHF.	11420763
Airway structure, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	Anti-inflammatory medications cause a reduction in the markers of airway inflammation, decrease the intensity of airway hyperresponsiveness, and improve clinical symptoms of asthma.	11421896
Inflammation, Skin lesion, Data types - Address	Altered Intercellular Communication	A recent study has shown that inducible nitric oxide synthase (iNOS) is expressed in the atopic skin lesion, suggesting the involvement of nitric oxide in the skin inflammation of AD.	11421931
Inflammation, Ulcer	Altered Intercellular Communication	Additional dermatological side-effects included focal areas of tender paronychial inflammation of toes and fingers and small aphthous ulcers of the oral mucosa.	11422037
Bronchitis	Altered Intercellular Communication	However, bronchial inflammation in more severe disease has not been extensively studied.	11422154
ARCN1 gene, Bronchitis	Altered Intercellular Communication	Bronchial inflammation in severe COPD is characterized by lower numbers of CD3+ and CD8+ cells and decreased numbers of CD3+ cells coexpressing the chemokine receptor CCR5.	11422154
Inflammation	Altered Intercellular Communication	Interactions among gastric somatostatin, interleukin-8 and mucosal inflammation in Helicobacter pylori-positive peptic ulcer patients.	11422469
Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Correlation between Helicobacter pylori infection, gastric inflammation and serum homocysteine concentration.	11422470
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	Moreover, there was no correlation between homocysteine level and gastric histology including H. pylori density, activity and inflammation scores, presence of atrophy or intestinal metaplasia.	11422470
Unknown (origin) (qualifier value)	Altered Intercellular Communication	A literature review indicated that idiopathic and inflammation-related PA dissection is extremely unusual.	11422480
Inflammation	Altered Intercellular Communication	The disease largely depends on T cells, but the biologic role of intestinal intraepithelial lymphocytes (IEL) in transmural inflammation remains poorly characterized.	11423175
Inflammation, Crohn Disease	Altered Intercellular Communication	Such perturbation of the IEL population within the ileal mucosa could contribute to the inflammation in Crohn disease.	11423175
Fibrosis, Liver, Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Hepatic artery resistance index and age were higher in patients with more severe liver fibrosis (respectively 0.638 +/- 0.084 and 39.0 +/- 10.9 (years) in mild fibrosis versus 0.687 +/- 0.060 and 49.4 +/- 14.4 (years) in severe fibrosis; P < 0.05 for both), whereas no difference between the two groups was found for the other histological features (degeneration, inflammation and necrosis), nor for portal flow velocity.	11424325
Fibrous, Inflammation	Altered Intercellular Communication	The increase in hepatic artery resistance index appears to be influenced by the extent of fibrous tissue deposition in the liver, determined by chronic inflammation and repair and, secondly, by ageing.	11424325
Alveolar, Inflammation, Lung diseases	Altered Intercellular Communication	Chronic obstructive bronchiolitis with organizing lung disease is an anatomoradioclinical entity characterized by nonspecific inflammation associated with recurrent migratory minimally dense alveolar opacities on the chest x-ray poorly responsive to corticosteroid therapy.	11424719
Inflammatory abnormality of the eye	Altered Intercellular Communication	Control of ocular inflammation as evidenced by decrease in inflammatory cells in both anterior and posterior chambers.	11425690
Inflammatory abnormality of the eye	Altered Intercellular Communication	On excision of the iris masses, the ocular inflammation was controlled in both patients.	11425690
Granuloma, Sarcoidosis, Inflammatory abnormality of the eye	Altered Intercellular Communication	The authors hypothesize that iris granulomas may not only be products of persistent antigenic stimulation characteristic of sarcoidosis but subsequently become foci of continued cytokine production and ocular inflammation.	11425690
Complex Regional Pain Syndromes	Altered Intercellular Communication	In the light of our observations, it seems unlikely that CRPS is a simple exaggeration of post-traumatic inflammation.	11427328
Inflammation, Fibrosis Assessment, Necrosis with inflammation	Altered Intercellular Communication	Patients with hepatic bile duct injuries had a significantly higher frequency of HCV genotype 1b; a higher mean serum globulin level; significantly higher mean scores for histological periportal necro-inflammation, portal inflammation, and fibrosis; and more severe portal lymphoid aggregation/follicles when compared with patients without hepatic bile duct injuries (P < 0.05, all).	11428585
Communicable Diseases, Inflammation	Altered Intercellular Communication	Multivariate logistic regression analysis showed that HCV genotype 1b infection, portal inflammation, and lymphoid aggregation/follicles were significant independent predictors associated with hepatic bile duct injuries.	11428585
Communicable Diseases, Hepatitis C, Chronic, Portal inflammation, Traumatic injury	Altered Intercellular Communication	The presence of hepatic bile duct injuries in Chinese patients with chronic hepatitis C was significantly correlated with HCV genotype 1b infection, and the patients with these injuries had more severe portal inflammation and formation of lymphoid aggregates/follicles.	11428585
Pain Distress Question, Inflammation	Altered Intercellular Communication	However, little is known on how heel elevation may contribute to a decrease in the pain and inflammation.	11428764
Inflammation, polychondritis	Altered Intercellular Communication	Relapsing polychondritis is a rare condition characterized by inflammation and subsequent degeneration of cartilages.	11429073
Inflammation, Neoplasms	Altered Intercellular Communication	In the UC-LD without neoplasm group, MSI> or =2 was detected significantly more frequently in patients with severe inflammation than in those with mild inflammation (six of nine v none of five; p = 0.028).	11429424
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	A high incidence of MSI in long standing UC with severe inflammation probably reflects genomic instability caused by repeated inflammatory stress.	11429424
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Thus, the influence of inflammation should be considered when estimating MSI in UC.	11429424
Inflammation, nervous system disorder, Traumatic injury, Torticollis, Disease	Altered Intercellular Communication	The differential diagnosis of acquired torticollis in infants and children comprises a large variety of disorders, including inflammation, neurologic disease or trauma.	11430724
Bone Marrow Diseases, Inflammation	Altered Intercellular Communication	Human T-lymphotropic virus type I (HTLV-I)-associated myelopathy (HAM) is characterized by chronic inflammation of the spinal cord.	11431014
Enterocolitis, Neutropenic, Perforation (observation), Necrosis	Altered Intercellular Communication	Neutropenic enterocolitis (NE) is a clinicopathologic condition characterized by bowel wall inflammation, which can proceed to necrosis and perforation.	11431780
Pancreatic Diseases, Venous Thrombosis, Inflammation, Neoplasms	Altered Intercellular Communication	Spleen vein thrombosis is more often caused by pancreatic disease (inflammations, tumors).	11432260
Necrotizing granulomatous inflammation, Tuberculoma, Constrictive pericarditis due to Mycobacterium tuberculosis complex	Altered Intercellular Communication	Pathologic examination of the pericardium and the right atrial mass both revealed chronic granulomatous inflammation with acid-fast bacilli and confirmed the diagnosis of tuberculous constrictive pericarditis and right atrial tuberculoma.	11432313
Inflammation, Cranial Arteritis	Altered Intercellular Communication	The occipital artery can show an inflammation in cranial arteritis.	11432796
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Of the colour Doppler sonographic (CDS) parameters only PSV was influenced by the degree of chronic inflammation, as shown at the MSG biopsy, suggesting that PSV may reflect the vascular changes occurring in the salivary glands during the course of an autoimmune disease such as pSS.	11434476
Adenoma	Altered Intercellular Communication	Co-expression of gonadotropin-releasing hormone receptor (GnRH-R) mRNA was also assessed to see whether this feature was associated with adenoma subtype and SSTR status.	11434667
Hyperprolactinemia, Breast Carcinoma	Altered Intercellular Communication	Moreover in any case of hyperprolactinemia we suggest a mammographic examination and, in the case of breast cancer, at least a baseline hormonal profile.	11434671
Gastrointestinal inflammation	Altered Intercellular Communication	Assessment of the usefulness of a diagnostic test: a survey of patient preference for diagnostic techniques in the evaluation of intestinal inflammation.	11434868
Eosinophilic disorder, Allergic, Inflammation, Bronchitis	Altered Intercellular Communication	In conclusion, an allergic profile of inflammation can also occur in CB: the marked upregulation of RANTES in the epithelium and subepithelium most likely accounts for the increased eosinophilia associated with an exacerbation of bronchitis.	11435248
Interstitial Cystitis, Chronic ulcerating interstitial cystitis, Cystitis	Altered Intercellular Communication	The classic type of interstitial cystitis is characterized by Hunner's ulcers, which are focal regions of severe bladder inflammation.	11435840
Inflammation, Necrosis	Altered Intercellular Communication	Centrilobular hepatocyte necrosis correlated with hepatic venular endothelial inflammation and centrilobular inflammation but not with rejection related features in portal tracts or with PRI.	11435966
Inflammation, Glucocorticoid deficiency with achalasia, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Clinically, abdominal aortic aneurysms (AAAs) display a spectrum of inflammation that extends from apparently noninflamed (degenerative) AAAs to the classic inflammatory variant.	11436079
Inflammation, Atherosclerosis	Altered Intercellular Communication	AAA tissues thereby exhibited a distinct pattern of gene expression reflecting chronic inflammation, extracellular matrix degradation, atherosclerosis, and smooth muscle cell depletion.	11436088
allergic inflammation	Altered Intercellular Communication	It is known that several inflammatory cells and cytokines play a role in allergic inflammation.	11436971
allergic inflammation	Altered Intercellular Communication	Furthermore, there are seasonal changes in several mediators responsible for allergic inflammation.	11436971
Inflammation, Calcinosis	Altered Intercellular Communication	Because TGase activity promoted apatite deposition, our findings potentially implicate inflammation in the pathogenesis of cartilage matrix calcification.	11438463
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Application of triple immunohistochemistry to characterize amyloid plaque-associated inflammation in brains with Alzheimer's disease.	11440311
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation, characterized by the presence of activated microglia and reactive astrocytes (gliosis), has been described in Alzheimer's disease (AD).	11440311
Inflammation, Data types - Address	Altered Intercellular Communication	The results of the triple IHC protocol clarified the spatial relation of microglia and astrocytes with amyloid plaques and provoked novel interpretations about the roles of inflammation in AD brain tissues.	11440311
Inflammation	Altered Intercellular Communication	Some of the amyloid plaques were not associated with inflammation while others were associated only with activated microglia.	11440311
Inflammation, Data types - Address	Altered Intercellular Communication	These findings suggest that amyloid plaques without associated inflammation may represent recently formed plaques and that the presence of amyloid plaques in AD brains may activate microglia prior to gliosis.	11440311
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Evaluation of C-reactive protein, a sensitive marker of inflammation, as a risk factor for stable coronary artery disease.	11440732
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Multiple lines of investigations have converged to suggest a prominent role for inflammation in coronary artery disease (CAD).	11440732
Inflammation	Altered Intercellular Communication	Efficient examinations for the exploration of acute nonspecific abdominal pain, such as the measurement of inflammation indicators, particularly serum activated protein C levels, graded-compression ultrasound scans and celioscopy, should be made available in the hospitals of African countries to increase the precision of diagnosis and to decrease the still too high frequency of appendectomies performed on principle.	11440889
Uremia, Inflammation	Altered Intercellular Communication	Increased activation of protein C, but lower plasma levels of free, activated protein C in uraemic patients: relationship with systemic inflammation and haemostatic activation.	11442482
Cancer-related fatigue, Inflammation	Altered Intercellular Communication	Systemic inflammation and activation of haemostasis are interrelated processes in CRF.	11442482
Inflammation, Hemorrhage, Fibrosis Assessment	Altered Intercellular Communication	To determine whether the reduced inflammation and bleeding and increased fibrosis reported in tobacco smokers affect the validity of clinical probing measurements by altering probe tip penetration.	11442742
Inflammation	Altered Intercellular Communication	This may be partly explained by the reduced inflammation and width of supra-bony connective tissue in smokers.	11442742
Deficit, Depressive disorder, Data types - Address, Unipolar Depression	Altered Intercellular Communication	Because a deficit in serotonergic neurotransmission is involved in major depression, we tried to find out whether 267C allele is associated with depressive disorders in AD.	11442897
RAPH1 gene, Endometrial adenocarcinoma	Altered Intercellular Communication	These cells were strongly positive for alpha inhibin and may have been the hormonal source responsible for the induction of the simultaneous LPD and endometrial adenocarcinoma.	11444203
Adenocarcinoma, Clear Cell, Structure of interstitial tissue of ovary, Endometriosis	Altered Intercellular Communication	It is proposed that endometriosis is not only a precursor of clear cell carcinoma but, through secondary hormonal induction of the surrounding ovarian stroma, may also provide a hormonal stimulus for diverse proliferative processes.	11444203
Ulcerative Colitis-Associated Colorectal Adenocarcinoma, Inflammation, Ulcerative Colitis, Intraepithelial Neoplasia	Altered Intercellular Communication	Two patient groups were selected: group A comprised 8 patients with ulcerative colitis-associated colorectal carcinomas, group B comprised 16 ulcerative colitis patients with risk factors (duration of disease, extent of inflammation, epithelial dysplasias).	11444475
Mastodynia, POLYDACTYLY, POSTAXIAL, WITH PROGRESSIVE MYOPIA, Premenstrual syndrome	Altered Intercellular Communication	Hormonal contraceptive usage was associated with significantly less mastalgia and premenstrual syndrome (PMS).	11446156
Sinusitis	Altered Intercellular Communication	In a phase IV, open-label study, 25 patients with clinically stable chronic sinusitis and persistent maxillary sinus inflammation were treated for 14 days with clarithromycin 500 mg twice daily.	11446271
Edema, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Statistically significant reductions (P < or = .05) from pretreatment were observed for all markers of sinus mucosal inflammation, including CD68, EG2, elastase, IL-6, IL-8, TNF-alpha, and edema score, with a trend to decreased total eosinophil count.	11446271
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Significant reductions in various markers of sinus mucosal inflammation support the role of clarithromycin in modulating immunologic responses.	11446271
Inflammation, Vasculitis, CTCAE, Sinobronchial syndrome	Altered Intercellular Communication	The vasculitis might have been caused by the chronic inflammation in the lungs associated with sinobronchial syndrome.	11446684
Inflammation, Malnutrition, Anemia	Altered Intercellular Communication	Using a multiparameter score, anemia correlated significantly with parameters of malnutrition (P=0.0001) but not with iron deficiency (P=0.5) or with inflammation (P=0.08).	11446733
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Our results suggest that inflammation or other mechanisms underlying elevated CRP values may contribute to the increased CHD risk among Indian Asians.	11447077
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Between histopathologist 1 (90.6%) and histopathologist 2 (81%), the absence of esophageal mucosal inflammation correlated best with normalized pH monitoring.	11448380
Refractory anemias, Inflammation, Destruction of tissue	Altered Intercellular Communication	Reactive oxygen intermediates (ROI) are together with prostanoids, leukotrienes and proteases, believed to be the mediators of inflammation and responsible for the pathogenesis of tissue destruction in RA.	11448551
Inflammation	Altered Intercellular Communication	Fiberbronchoscopic findings remained unremarkable, except for the bronchial biopsy specimen, which showed moderate eosinophilic inflammation of the mucosa and marked thickening of the subepithelial layer.	11449611
Inflammation, Bronchial Hyperreactivity, Coughing, Eosinophilic disorder, Bronchitis, Asthma	Altered Intercellular Communication	Since hyperresponsiveness and cough are phenotypic hallmarks of cough variant asthma, in eosinophilic bronchitis--beside cough--another two features of asthma are present: eosinophilic inflammation of the mucosa along with sputum eosinophilia and subepithelial layer thickening.	11449611
Cough variant asthma, Asthma, Bronchitis	Altered Intercellular Communication	Not surprisingly, eosinophilic bronchial inflammation could be shown in patients with cough variant asthma as well, who--up to 56% during a four year-period--develop classic asthma.	11449611
Hormone abnormality, Sexual Dysfunction, Liver Cirrhosis	Altered Intercellular Communication	Liver cirrhosis is frequently associated with sexual dysfunction and hormonal abnormalities.	11451164
Sepsis, Inflammation, Communicable Diseases, Necrosis	Altered Intercellular Communication	The development of inflammation and sepsis in such patients is determined by the extent of involvement, infection of necrotic zone, and disease duration.	11452764
Cholecystitis	Altered Intercellular Communication	In the presence of acute gallbladder inflammation we dissect the gall-blader well with a suction-irrigation tube.	11452824
Inflammation, Bile duct calculus, Bile duct structure	Altered Intercellular Communication	In patients suspected of having common bile duct stones, biliary duct injuries and/or anatomical changes due to inflammation, we perform intraoperative cholangiography.	11452824
Sacroiliitis, Inflammation	Altered Intercellular Communication	99mTc-NS was neither specific nor sensitive enough in the detection of sacroiliitis although it could be helpful for the confirmation of inflammation.	11453052
Inflammation	Altered Intercellular Communication	Interleukin-6 (IL-6) has been considered as an important mediator of inflammation.	11453540
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To compare a low field dedicated extremity magnetic resonance imaging system (E-MRI) with x ray and clinical examination, in the detection of inflammation and erosive lesions in wrist and metacarpophalangeal (MCP) joints in newly diagnosed, untreated rheumatoid arthritis (RA).	11454641
Sore to touch, Joints, Synovial Hypertrophy, Swelling	Altered Intercellular Communication	Synovial hypertrophy grades were significantly higher in RA joints with clinical signs of joint inflammation-that is, swelling and/or tenderness (median 3, 5th-95th centile 1-4) than without these clinical signs (median 2, 5th-95th centile 1-3), p < 0.001.	11454641
Breast Carcinoma	Altered Intercellular Communication	We hypothesize that genes involved in endocrine signaling may modify the BRCA1/2-associated age-specific breast cancer penetrance.	11454686
Inflammation, Data types - Address	Altered Intercellular Communication	Our study demonstrates a decreased production of the anti-inflammatory compound IL-1ra, suggesting a propensity towards inflammation in patients with AD.	11455132
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The amniotic membrane-covered area showed rapid epithelization, reduced inflammation and suppressed fibrosis formation.	11456023
Airway structure, Respiratory Hypersensitivity	Altered Intercellular Communication	Effects of suplatast tosilate on airway inflammation and airway hyperresponsiveness.	11456386
eosinophil, Respiratory Hypersensitivity, Eosinophilic inflammation	Altered Intercellular Communication	Suplatast tosilate was considered to have inhibited airway eosinophilic inflammation through decreases in peripheral blood eosinophils counts and in ECP levels in induced sputum, which resulted in inhibition of airway hyperresponsiveness.	11456386
Inflammation	Altered Intercellular Communication	Peptidoglycan may thus contribute to T- and B-cell activity during brain inflammation without a requirement for local bacterial replication.	11459746
Cataract, Inflammatory disorder	Altered Intercellular Communication	Corticosteroids used before and after surgery reduced inflammation disorders but seemed to speed up the onset of secondary cataract.	11460054
Cataract, Inflammation	Altered Intercellular Communication	Despite fairly frequent inflammation and secondary cataract, posterior chamber lens implantation in children is well tolerated.	11460054
Temporal headache, Inflammation	Altered Intercellular Communication	The history disclosed temporal headache and the examination showed inflammation in temporal artery.	11460198
Inflammation	Altered Intercellular Communication	Formaldehyde may cause cytotoxicity, which induces inflammation and release of more SSAO, producing a cascade of toxic cycle.	11461168
Airway structure, Asthma	Altered Intercellular Communication	Previous studies have reported that ST2 is preferentially expressed on Th2 cells and plays a critical part in controlling airway inflammation in murine models of asthma.	11463601
Allergic asthma, allergic inflammation	Altered Intercellular Communication	These results suggest that soluble human ST2 protein in sera may be related to Th2-mediated allergic inflammation inducing acute exacerbation in patients with atopic asthma.	11463601
prostatitis	Altered Intercellular Communication	Prostate inflammation proves to be a significant factor contributing to serum PSA elevation up to 10 ng/ml among patients with nonsuspicious DRE.	11464034
Inflammation, Demographics Domain, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation is hypothesized to play a role in development of type 2 diabetes mellitus (DM); however, clinical data addressing this issue are limited.	11466099
Inflammation, Fibrosis Assessment, Thickened, Arteritis	Altered Intercellular Communication	it is assumed that there are two types of arteritic inflammation: (1) the occlusion of intra-arterial space due to intimal fibrosis (UBM: high reflexive "filling"), and (2) inflammation of the perivascular zone with oedematous thickening and infiltration of the media (UBM: dark halo) and its combination.	11466252
Inflammation, Atherosclerosis	Altered Intercellular Communication	Development and progression of atherosclerosis involves recruitment and binding of circulating leukocytes to areas of inflammation within the vascular endothelium mediated by a diverse array of cellular adhesion molecules.	11466561
Complication Aspects, Specimen Source Codes - Abscess, Communicable Diseases, Specimen Type - Fistula, Diabetic Angiopathies, Stasis, Intestinal Obstruction, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Both diseases were associated with similar sets of GI complications, such as intestinal obstruction and stasis, mucosal inflammation and infection, vascular complications, and complications related to fistula and abscess formation.	11467640
Airway structure, Ulcerative Colitis, Colitis	Altered Intercellular Communication	His evaluation showed large airway inflammation with fibrinopurulent debris and colonic inflammation and ulcerations consistent with UC.	11468448
Hepatitis	Altered Intercellular Communication	Serum AST > 40 and/or ALT > 40 U/L was defined as liver inflammation.	11470392
Hepatitis	Altered Intercellular Communication	Adjusted odds ratios of liver inflammation were 1.00 (reference), 0.80, 0.69, and 0.61 for men drinking < 1, 1-2, 3-4, and > or = 5 cups of coffee daily, respectively.	11470392
Hepatitis	Altered Intercellular Communication	Among 6898 men without liver inflammation, serum AST and ALT were inversely associated with coffee consumption, and alcohol-related rise in AST was attenuated with coffee drinking.	11470392
Hepatobiliary Disorder, Communicable Diseases, Actual blood loss, Inflammation	Altered Intercellular Communication	We suggest this effect results from possible increased occult blood loss and a cytokine-mediated effect on SF in subjects with inflammation, infection, or liver disease.	11470724
Heart Diseases, Inflammation	Altered Intercellular Communication	The relations between aspirin, inflammation, and SF may confound epidemiologic associations between elevated SF, as an indicator of iron stores, and heart disease risk.	11470724
Trachoma , Inflammation	Altered Intercellular Communication	More than half (51.1%) of the children aged 10 years or less had active trachoma (trachomatous inflammation, TI, in 16.5% and trachomatous follicles, TF, in 34.6%).	11471081
Sample Size Calculation, Inflammation	Altered Intercellular Communication	These suggest that elevated sL-selectin levels and decreased frequency of L-selectin+ CD8(+) T cells in SSc patients may be involved in inflammation associated with SSc.	11472411
Inflammation, Necrosis, Pain Distress Question	Altered Intercellular Communication	Acinar necrosis and acute inflammation were seen more often in patients with persistent pain than in those who were pain free (P =.081).	11473456
Inflammation	Altered Intercellular Communication	Since the Tc-99m labelled monoclonal anti-NCA 90 granulocyte antibody Fab' fragment MN3 (MN3 Fab') might be of interest for imaging abdominal inflammation which could be hampered by nonspecific bowel activity, we prospectively investigated the appearance of bowel activity in MN3 Fab' imaging.	11475075
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Abdominal inflammation was excluded clinically and there were no signs of inflammatory bowel disease in the patients' histories.	11475075
Inflammation, Keratosis	Altered Intercellular Communication	The rapid appearance of solitary seborrheic keratoses with associated inflammation, seen clinically and histologically, may be an early sign of Leser-Trelat-syndrome.	11475649
Asthma, Bronchial Hyperreactivity	Altered Intercellular Communication	A relationship between nonspecific bronchial hyperresponsiveness and allergic airway inflammation has been reported in children and in adults with asthma, but the relationship in infants with asthma is still unclear.	11476459
Candida endophthalmitis, Uveitis	Altered Intercellular Communication	To describe clinical and/or histopathologic features that could help distinguish endogenous Candida endophthalmitis from endogenous Aspergillus intraocular inflammation and to provide histologic documentation of intraocular spread of these agents.	11476686
Cataract, Intraocular inflammation, Optic Nerve	Altered Intercellular Communication	Nine months after cataract surgery with posterior chamber lens implant, a 79-year-old man receiving topical corticosteroids in the same eye presented with best-corrected visual acuity of 20/60, a superior visual field defect, and optic nerve edema without intraocular inflammation.	11476692
Gastrointestinal inflammation	Altered Intercellular Communication	In a prospective study, 62 patients who were suspected of having intestinal inflammation and 30 control subjects were enrolled.	11477240
Gastrointestinal inflammation	Altered Intercellular Communication	In the detection of intestinal inflammation, findings at 99mTc (V) DMSA scintigraphy were as follows: true-positive in 55, false-positive in two, true-negative in 32, and false-negative in three.	11477240
Gastrointestinal inflammation	Altered Intercellular Communication	Our results show that 99mTc (V) DMSA scintigraphy is a useful noninvasive diagnostic test for the detection and localization of intestinal inflammation.	11477240
Sarcoma, Hemangioma, Granulomatous inflammation	Altered Intercellular Communication	Hemangiomas (n = 12, 41%) and metastatic sarcomas (n = 6, 21%) comprised the largest categories, followed by granulomatous inflammation (n = 3, 10%).	11477711
Respiratory System, Inflammation, Saint Lucia	Altered Intercellular Communication	Ligneous inflammation of the upper and lower respiratory tract must be considered in children with LC and recurrent respiratory tract problems.	11477736
Airway structure, Asthma, Bronchitis	Altered Intercellular Communication	[Study on the pathological features of airway inflammation in asthma and chronic bronchitis].	11477894
Airway structure, Asthma, Bronchitis	Altered Intercellular Communication	To explore the difference between the pathological features of asthma and chronic bronchitis on airway inflammation, then to provide pathomorphological basis for appropriate diagnosis and treatment of these two different entities.	11477894
Inflammation, Cystic Fibrosis, Fibrosing colonopathy	Altered Intercellular Communication	Two patients with cystic fibrosis had diffuse colonic narrowing; a diagnosis of enzyme-induced fibrosing colonopathy was made in one and nonspecific inflammation was found in the other.	11479408
Airway structure	Altered Intercellular Communication	At first the family inquiry into the chronic airway inflammation history and smoking index > or = 300 were made in population aged 15 years or more.	11480081
ARCN1 gene, Airway structure	Altered Intercellular Communication	The prevalences of COPD in smokers, subjects with chronic airway inflammation history and both of them were 24.6%, 34.7% and 40.4%, respectively.	11480081
Airway structure, ARCN1 gene	Altered Intercellular Communication	The sole smoking accounted for 40.7% and chronic airway inflammation history for 28.4% in the all COPD causes, respectively.	11480081
ARCN1 gene, Chronic pulmonary heart disease, Airway structure	Altered Intercellular Communication	The primary causes of COPD and chronic cor pulmonale are smoking and chronic airway inflammation.	11480081
Inflammation, Atrophic	Altered Intercellular Communication	Evaluation of gastric biopsies revealed an overall decline in chronic inflammation and atrophy.	11480494
Inflammation, Plasma Cells, Granuloma	Altered Intercellular Communication	Depending upon the presence of characteristic cytologic findings, the cases were divided into five major groups: acute inflammation with giant cells, histiocytic granulomas, epithelioid cell granulomas, plasma cell type and mixed histioplasmacytic type.	11480717
Inflammation, Calcinosis, Pilar cyst	Altered Intercellular Communication	Young pilar cysts showed aspirates with an abundant background of blotchy keratin with or without calcification and inflammation.	11480722
Hepatitis	Altered Intercellular Communication	All 3 peginterferon alfa-2b doses decreased liver inflammation to a greater extent than did interferon alfa-2b, particularly in subjects with sustained responses.	11481625
Inflammation, Kidney Failure	Altered Intercellular Communication	The renal failure was not improved by PSL, but, together with the inflammation, responded to the combination of PSL and CPA.	11481823
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	Histopathological results showed statistically significant differences (p < 0.05) between eradicated and non eradicated patients in terms of severity of inflammation and intestinal metaplasia, but not in terms of atrophy.	11482041
Sepsis, Inflammation, Pancreatitis	Altered Intercellular Communication	[Inflammation response syndrome, sepsis and multi-organ insufficiency in patients operated for destructive pancreatitis].	11482186
Inflammation, Esophagus, Hiatal Hernia, Affection	Altered Intercellular Communication	Esophageal contracture occurs in presence of its cicatricial changes and is characterized by shortening of the organ, the hiatal hernia of diaphragm formation and reflux-oesophagitis, which supports inflammation in the oesophagus and prevents epithelization of the affection zone, causing further stenosing.	11482210
Esophageal	Altered Intercellular Communication	Performance of the oesophageal contracture correction in children had permitted to prevent oesophageal inflammation, to restrict the stenosis progress, secured to do segmental oesophageal resection in 2 observations.	11482210
Inflammation	Altered Intercellular Communication	The coexistence of diverse lesions in our case might represent the pluripotentiality of the urothelium in association with chronic inflammation and neoplastic induction.	11482582
Inflammation, Traumatic injury	Altered Intercellular Communication	The nasal septum was biopsied in 71 cases, and histology showed non-specific or non-diagnostic findings in 39 (55 per cent), chronic inflammation in 12 (17 per cent), acute inflammation in six (eight per cent), acute to chronic inflammation in four (six per cent) and histological changes consistent with trauma in nine (13 per cent).	11485583
Sjogrens Syndrome", Inflammation, Autoimmune Diseases, Aplasia of Lacrimal and Salivary Glands	Altered Intercellular Communication	Sjogren's syndrome is an autoimmune disease characterized by inflammation and destruction of lacrimal and salivary glands.	11485925
diabetic	Altered Intercellular Communication	We used nonobese diabetic mice, which develop autoimmune-mediated lacrimal gland inflammation, as an experimental model to define the adhesion molecules that control lymphocyte migration into inflamed lacrimal glands.	11485925
Dacryoadenitis	Altered Intercellular Communication	These adhesion molecules offer potential therapeutic targets to block the development of lacrimal gland inflammation and destruction.	11485925
Inflammation, Tissue injury	Altered Intercellular Communication	Uncontrolled expression of matrix metalloproteinases (MMPs) can result in tissue injury and inflammation.	11486102
Intraocular inflammation	Altered Intercellular Communication	Treatment with doxycycline led to improvement in the intraocular inflammation but resulted in a poor visual outcome.	11486295
Inflammation	Altered Intercellular Communication	The amount of bFGF was also significantly higher in the group of patients with high degree of inflammation.	11486445
Inflammation, physiopathological	Altered Intercellular Communication	Although elderly persons regularly consume nonsteroidal anti-inflammatory drugs (NSAIDs), it is not clear that NSAIDs alleviate muscle dysfunction and/or inflammation following injurious exercise.	11487604
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Physiologic increases may occur in patients with immunosuppression, chronic inflammation, and autoimmune disorders.	11488062
Inflammation, Fatty degeneration	Altered Intercellular Communication	Steatosis was present in 59.7% of patients with inflammation in 32.4% of cases.	11488074
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	These patients were older, had higher sinusoidal iron scores, and had a higher prevalence of steatosis and inflammation than patients without fibrosis.	11488074
Inflammation, Complication	Altered Intercellular Communication	Therefore the otorhinolaryngologist is confronted increasingly with these problems and questions for surgery, especially if the symptom of a periorbital inflammation occurs as a sign for a beginning orbital complication and radiological signs of involvement of the paranasal sinuses exist.	11488151
Fungal sinusitis, Inflammation, Sinusitis	Altered Intercellular Communication	In immunosuppressed patients with clinical and radiological signs for a sinusitis and a periorbital inflammation an invasive fungal sinusitis should be considered.	11488151
Airway structure, Asthma	Altered Intercellular Communication	Measurement of nitric oxide in exhaled air is a noninvasive method to assess airway inflammation in asthma.	11488323
Inflammation	Altered Intercellular Communication	If this is the case, it could be speculated that T-cell inflammation is a response to antigenic stimuli originating in the lung and induced by cigarette smoking.	11488331
Inflammation	Altered Intercellular Communication	In all cases, this revealed demyelination in the proximal (CNS) part of the nerve root, with associated gliosis and variable inflammation.	11489143
Bacterial prostatitis, prostatitis, Premature Ejaculation	Altered Intercellular Communication	Prostatic inflammation was found in 56.5% and chronic bacterial prostatitis in 47.8% of the subjects with premature ejaculation, respectively.	11489699
prostatitis, Premature Ejaculation	Altered Intercellular Communication	Considering the role of the prostate gland in the mechanism of ejaculation, we suggest a role for chronic prostate inflammation in the pathogenesis of some cases of premature ejaculation.	11489699
Inflammation	Altered Intercellular Communication	The increased bacterial density and inflammation are expected in cardiac mucosa because of low acid secretion.	11490831
Inflammation	Altered Intercellular Communication	T helper type 1 (Th1) immune response with increased IFN-gamma also contributes to the inflammation of the gastric mucosa.	11491045
Bronchitis	Altered Intercellular Communication	Changes in bronchial inflammation during acute exacerbations of chronic bronchitis.	11491152
Bronchitis, Chronic, Bronchitis	Altered Intercellular Communication	There are little data describing noncellular changes in bronchial inflammation during exacerbations of chronic bronchitis.	11491152
Airway structure, Chronic Obstructive Airway Disease, Bronchitis	Altered Intercellular Communication	The relationship between sputum colour and airway inflammation at presentation has been assessed during an exacerbation in patients with chronic bronchitis and a primary care diagnosis of chronic obstructive pulmonary disease.	11491152
Inflammation, Exacerbation	Altered Intercellular Communication	Mucoid exacerbations were associated with little bronchial or systemic inflammation at presentation, and sputum bacteriology was similar to that obtained in the stable state.	11491152
Inflammation, Exacerbation	Altered Intercellular Communication	Purulent exacerbations were associated with marked bronchial and systemic inflammation (p < 0.025 for all features) and positive sputum cultures (90%).	11491152
Bronchitis, Chronic, Inflammation	Altered Intercellular Communication	The presented results indicate that exacerbations of chronic bronchitis, defined by sputum colour, differ in the degree of bronchial and systemic inflammation.	11491152
Inflammation, Bacterial Infections, Exacerbation	Altered Intercellular Communication	Purulent exacerbations are related to bacterial infection, and are associated with increased neutrophilic inflammation and increased leukotriene B4 concentrations.	11491152
Pancreatitis, Pancreatitis Necrotizing	Altered Intercellular Communication	The extent of pancreatic inflammation was classified according to Balthazar grade, and intrapancreatic necrosis on these examinations was prospectively assessed and compared with clinical and biologic data and with patient outcomes.	11491444
Pain Distress Question, Swelling, Inflammation	Altered Intercellular Communication	Clinicalfindings included pain, as a summation of 3 categories (pain at rest, pain in motion and pain in passive motion, each assessed on a 4-step rating scale), and inflammation, also as a summation of 3 categories (swelling, patellar ballotement and local warmth, each assessed on a 4-step rating scale).	11491492
Pain Distress Question, Inflammation	Altered Intercellular Communication	Significant improvement in pain symptoms (p < 0.0001), inflammation (p < 0.0001), VAS pain (p < 0.001) and SFV (p < 0.05) were observed after the 5 injections.	11491492
Refractory anemias, Inflammation	Altered Intercellular Communication	SI-6601D improved local clinical symptoms in RA patients by suppressing PGE2 and, therefore, may be a useful treatment for local inflammation in RA.	11491492
Sample Size Calculation, Myocarditis	Altered Intercellular Communication	Myocardial inflammation andfibrosis are common autopsyfindings in systemic sclerosis (SSc) and, although symptomatic cardiac involvement occurs less often, current therapies remain empiric and do not prevent or modify its course.	11491499
Inflammation	Altered Intercellular Communication	We conclude that matrix metalloproteinase-9 represents a non-specific marker of systemic inflammation.	11493234
Inflammation, Atherosclerosis	Altered Intercellular Communication	The generation of higher cholesterol blood levels is proposed as a possible link between chronic periodontal inflammation and atherosclerosis.	11493357
Inflammation, trauma to the abdomen	Altered Intercellular Communication	closed abdominal injury, and suppurative inflammation of soft tissues were examined.	11494903
Inflammation	Altered Intercellular Communication	The COX-2 isoform is important in a variety of pathophysiological conditions such as inflammation and tumorigenesis.	11495083
Inflammation	Altered Intercellular Communication	This may lead to increased, localized mural neovascularization and inflammation, as well as regional wall weakening.	11496282
Craniocerebral Trauma, Inflammation, Epilepsy	Altered Intercellular Communication	Cardiological examination covered 115 patients (79 males and 36 females aged 16-44 years) with organic brain pathology of nonvascular genesis: epilepsy (n = 51), sequelae of closed craniocerebral trauma (n = 37) or cerebral inflammation (n = 27).	11496730
Inflammation, Acute Coronary Syndrome, Myocardial	Altered Intercellular Communication	To detect myocardial damage in severe systemic inflammation by cTnI measurements in patients without acute coronary syndromes.	11497154
Inflammation, Ischemic	Altered Intercellular Communication	This healing mode may follow ischemic death of physeal chondrocytes or be owing to another mechanism, e.g., release of mediatory substances of inflammation.	11497365
Communicable Diseases, Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Amplification of inflammation in emphysema and its association with latent adenoviral infection.	11500352
Pulmonary Emphysema	Altered Intercellular Communication	We conclude that cigarette smoke-induced lung inflammation is amplified in severe emphysema and that latent expression of the adenoviral E1A protein expressed by alveolar epithelial cells influenced this amplification process.	11500352
Granulomatous inflammation	Altered Intercellular Communication	Closed pleural biopsy on the left side showed granulomatous inflammation with early caseation.	11500710
Inflammation, Pain Distress Question	Altered Intercellular Communication	The clinical indices used for evaluation of inflammation included erythrocyte sedimentation rate (ESR), pain intensity, proximal interphalangeal (PIP) joint size, and Ritchie articular index.	11501728
Inflammation	Altered Intercellular Communication	In such patients, the pathogenetic mechanisms may differ from those in other subsets of patients with AMI and active inflammation may play a more important role in AMI onset.	11502046
Diffuse panbronchiolitis, Bronchiolitis, Bronchitis	Altered Intercellular Communication	T cells are important cellular components of bronchial inflammation in diffuse panbronchiolitis (DPB).	11502665
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Whether a common mechanism(s) of coagulation and inflammation contributes to both responses is unclear.	11502788
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Moreover, this study suggested that, in patients with UC, medical therapy not only leads to the recovery of acute inflammation but also restores mucosal barrier integrity and function.	11505209
Arthralgia, Inflammation, Exanthema, Edema	Altered Intercellular Communication	The acute onset of the syndrome, presenting purpuric rash, abdominal discomfort and asymmetric joint pain with edema and local signs of acute inflammation, was followed by several relapses over a 2 years period.	11506256
Inflammation	Altered Intercellular Communication	Skin biopsies were taken of three different groups of patients in which local inflammation of the skin might occur.	11506389
Inflammation, Fracture	Altered Intercellular Communication	Skin taken at the site of the femoral fracture showed no signs of inflammation.	11506389
Body tissue, Inflammation, Pain Distress Question	Altered Intercellular Communication	Acid-sensing ion channels (ASICs) are expressed by rat sensory neurons and may mediate pain associated with tissue acidosis after inflammation or injury.	11507351
Inflammation, Musculoskeletal Pain	Altered Intercellular Communication	Joint inflammation in polymyalgia rheumatica is regarded primarily as a disease of the synovial cavities and bursae, but the adjacent capsules and soft tissues have not been evaluated using sensitive imaging methods.	11508586
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The correlation of the HAI parameters with the variation of PIIIP showed significance only for fibrosis (r(s) = 0.36, P < 0.002) and portal inflammation (r(s) = 0.35, P < 0.01).	11508668
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	The response to a-IFN improved liver inflammation and fibrosis.	11508668
Hepatic inflammation	Altered Intercellular Communication	The percentage of Th1 cells increased significantly with the raise of hepatic inflammation activity.	11509144
Inflammation, Necrosis, Insemination, Artificial, Homologous, Fibrosis Assessment, Destruction (action), Cholangitis	Altered Intercellular Communication	Histologic features in PBC group consisted of cholangitis, destruction or proliferation of the bile duct and inflammation within the portal tract; while in AIH group inflammation, necrosis and fibrosis of periportal region, the aggregation of lymphocytes, mononuclear cells and plasma cells in the portal tract or periportal area were found.	11509150
Pneumonitis	Altered Intercellular Communication	CD18 dependency of transendothelial neutrophil migration differs during acute pulmonary inflammation.	11509630
Inflammation	Altered Intercellular Communication	More recent evidence suggests that selection may also depend on whether inflammation is chronic or acute, but why this is the case remains unknown.	11509630
Inflammation, Nephrotic Syndrome, Kidney Failure, Hypoalbuminemia	Altered Intercellular Communication	Older age, cause of renal failure, transport status, chronic inflammation, presence of nephrotic syndrome, and nutrition status are important determinants of hypoalbuminemia.	11510278
Inflammation, Hemorrhage	Altered Intercellular Communication	Autopsy showed hemorrhages in the mucosa in 68.2%, in soft tissues adjacent to tracheostoma in 41.4%, and suppurative inflammation in 15.2% cases.	11510353
Inflammation, Superinfection	Altered Intercellular Communication	Grommets alone cannot eradicate inflammation outside the middle ear cavity, but rather, they can aggravate it by superinfection.	11510732
Inflammation	Altered Intercellular Communication	We therefore recommend that controlling the radiation-induced inflammation in areas such as the ears, nose, sinuses, and nasopharynx is most important.	11510732
Inflammation	Altered Intercellular Communication	Increased LPL apoptosis is likely to downregulate mucosal inflammation whereas decreased IEL apoptosis could be responsible for autoimmune and malignant complications of CD.	11511560
Sepsis, Inflammation, Critical Illness	Altered Intercellular Communication	To investigate the role of macrophage migration inhibitory factor (MIF) as a marker of severity of systemic inflammation in patients with severe sepsis and critically ill postsurgical patients.	11511957
Communicable Diseases, Inflammation, septic	Altered Intercellular Communication	MIF serves as a general marker for systemic inflammation in septic and nonseptic acute critical illness, but MIF does not discriminate for severity or differentiate between infectious and noninfectious origins of an acute critical illness.	11511957
Squamous cell carcinoma of conjunctiva, Inflammation, Corneal Ulcer	Altered Intercellular Communication	We present an unusual case of conjunctival carcinoma with marked intraocular involvement, which appeared primarily as a chronic inflammation with corneal ulcer.	11512254
Weakness, Inflammation, Headache	Altered Intercellular Communication	All patients underwent rheumatological evaluation for number of positive tender points, number of tender and swollen joints, markers of inflammation, and presence of headache and weakness.	11515679
Inflammation, pelvic sepsis	Altered Intercellular Communication	Eight patients developed pelvic sepsis that demanded a secondary defunctioning loop ileostomy, and five showed symptoms arising from relapsing inflammation in residual rectal mucosa; in three of these, a secondary transanal mucosectomy covered by a loop ileostomy was necessary.	11515681
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Biopsies of the masses demonstrated noncaseating granulomatous inflammation and fibrosis similar to the pathology from her bowel resection.	11515853
Upper Respiratory Infections	Altered Intercellular Communication	Measuring plasma exudation in nasal lavage fluid and in induced sputum as a tool for studying respiratory tract inflammation.	11516750
Inflammation, Chronic sinusitis	Altered Intercellular Communication	We performed nasal lavage (NAL) combined with induced sputum to determine exudative inflammation in the upper and lower airways in patients with chronic sinusitis and in controls.	11516750
Inflammation, Granulomatous disorder, Neoplasms, Malignant Childhood Neoplasm	Altered Intercellular Communication	FNA cytologic diagnostic categories included reactive lymph node/non-specific inflammation (25 biopsies), benign cystic process (four), granulomatous disease (eight), malignant neoplasm (three), and benign neoplasm (one).	11518591
Malnutrition, Inflammation, Cardiac valve calcification	Altered Intercellular Communication	Association of inflammation and malnutrition with cardiac valve calcification in continuous ambulatory peritoneal dialysis patients.	11518787
Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	In view of the recent recognition of association among inflammation, malnutrition, and atherosclerosis, the possible role of inflammation and malnutrition in VC was investigated.	11518787
Inflammation, Atherosclerosis	Altered Intercellular Communication	The data suggest that VC not only is a passive degenerative process but also involves active inflammation, similar to that seen in atherosclerosis.	11518787
Inflammation, Atherosclerosis	Altered Intercellular Communication	The data also indicate that VC and atherosclerosis should be considered as associated syndromes, sharing similar pathogenic mechanisms, namely active inflammation.	11518787
Airway structure	Altered Intercellular Communication	Airway smooth muscle (ASM) is a potential source of multiple proinflammatory cytokines during airway inflammation.	11520738
Iritis	Altered Intercellular Communication	Topical steroid only was administered to the patient whose donor graft was over 8.5 mm and with a heavy iris inflammation 2 weeks after PKP.	11520759
Tumor necrosis, Inflammation	Altered Intercellular Communication	The mRNA expression of MMP-7 and -9, but not of other metalloproteinases [MMP-2 and -3, and tumour necrosis factor (TNF)-alpha-converting-enzyme] was equally upregulated throughout all stages of lesion formation with active inflammation, and in most of matched NAWM tissue.	11522577
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Increased numbers of eosinophils (up to 400 cells/mm(2)) were observed in active, fulminant inflammation in both CD and UC, this being related to the severity of inflammation and not the diagnosis of the two disorders.	11523058
Airway structure, Asthma	Altered Intercellular Communication	These results showed that detection of exhaled CO could be a simple non-invasive tool for monitoring airway inflammation and acute exacerbation of asthma.	11523156
Cataract, Inflammation	Altered Intercellular Communication	Comparison of ketorolac tromethamine 0.5% and rimexolone 1% to control inflammation after cataract extraction.	11524195
Cataract, Inflammation	Altered Intercellular Communication	To compare the efficacy of a topical nonsteroidal anti-inflammatory agent (ketorolac tromethamine 0.5%) with that of a topical steroid (rimexolone 1%) to control inflammation after cataract surgery.	11524195
Cataract, Inflammation	Altered Intercellular Communication	Ketorolac tromethamine 0.5% was as effective as rimexolone 1% in reducing inflammation after cataract surgery.	11524195
MS gene, Inflammation, Inflammatory disorder, Fatigue	Altered Intercellular Communication	To test the hypothesis that fatigue in MS is related to inflammatory disease activity as measured by systemic markers of inflammation.	11524478
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Inflammation plays an important role in acute coronary syndromes, and some evidence indicates that patients with a more pronounced vascular inflammatory response have a poorer outcome.	11524640
Gingivitis, Dental Plaque	Altered Intercellular Communication	Both dentifrices resulted in statistically significant reductions in dental plaque, gingival inflammation, and stain at all time periods compared to baseline.	11524866
Inflammation, Dental Plaque	Altered Intercellular Communication	Plaque size, the mode of arterial remodeling and histopathologic characteristics of plaque vulnerability (lipid-rich core and plaque inflammation) were compared between right and left femoral arteries obtained from the same individual.	11527623
Inflammation, Dental Plaque	Altered Intercellular Communication	There was concordance in average plaque size (r(2) = 0.5, p < 0.001), expansive remodeling (kappa = 0.42, p = 0.007) and occurrence of plaques containing a large lipid-rich core (kappa = 0.60, p = 0.001), but no concordance in plaque inflammation (kappa = 0.067, p = 0.61) between right and left arteries.	11527623
Inflammation, atherosclerotic	Altered Intercellular Communication	The nonhomogeneous distribution of inflammation in atherosclerotic arteries supports the hypothesis that plaque inflammation is locally affected.	11527623
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Two small nodules were excised and submitted for histopathological study, which showed discrete granulomatous inflammation with caseating necrosis.	11529324
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	The inflammation is typically granulomatous with associated vasculitis.	11529927
Inflammatory abnormality of the eye, Systemic disease	Altered Intercellular Communication	Serologic investigations were positive for Epstein-Barr virus antibodies and antinuclear antibodies, but no evidence of systemic disease or other causes of ocular inflammation was found.	11530065
Intraocular inflammation	Altered Intercellular Communication	Kikuchi-Fujimoto disease may be associated with intraocular inflammation.	11530065
Airway structure, Asthma	Altered Intercellular Communication	This study suggests that airway inflammation persists in some severe asthma patients despite inhalation of FP 800 micrograms.	11530386
Inflammation, Necrosis	Altered Intercellular Communication	Touch imprint cytology of the excised lump was consistent with a granulomatous inflammation while histopathological examination documented a NSGM with central necrosis.	11530868
Inflammation, Melanosis	Altered Intercellular Communication	To investigate the incidence of melanosis of the vermiform appendix in a paediatric population, and look for correlations with season, apoptotic rate and inflammation as possible causes.	11532034
Respiratory Syncytial Virus Infections, Pneumonitis	Altered Intercellular Communication	Because RSV replication is restricted to airway epithelial cells, where RSV replication induces potent expression of chemokines, the epithelium is postulated to be a primary initiator of pulmonary inflammation in RSV infection.	11533168
Upper Respiratory Infections	Altered Intercellular Communication	These data profile the temporal changes in expression by RSV-infected lower airway epithelial cells of chemokines, chemotactic proteins which may be responsible for the complex cellular infiltrate in virus-induced respiratory inflammation.	11533168
Gingivitis, Hemorrhage, Bone Diseases, Contusions, Petechiae	Altered Intercellular Communication	The condition is characterized by perifollicular petechiae and bruising, gingival inflammation and bleeding, and, in children, bone disease.	11533373
Acne	Altered Intercellular Communication	However, several cases have now been described in patients with no preceding history of acne or other inflammatory conditions.	11534909
Inflammatory abnormality of the eye, Conjunctival scar	Altered Intercellular Communication	Patients' symptoms, ocular inflammation, conjunctival scarring, complete blood cell count (including reticulocyte count).	11535451
Choroidal Effusions, Orbital Pseudotumor	Altered Intercellular Communication	The mechanism of angle closure is anterior rotation of the ciliary body secondary to choroidal effusions resulting from the orbital inflammation.	11535457
Inflammation	Altered Intercellular Communication	Inflammation was not a confounding factor, but DNA migration increased significantly with age in nonsmokers (r = 0.68; P = 0.014).	11535552
Hyperhidrosis disorder	Altered Intercellular Communication	Biochemical and hormonal changes in endurance trained volunteers during and after exposure to bed rest and chronic hyperhydration.	11543213
Inflammation, Head and neck structure	Altered Intercellular Communication	Differences among tonsillar FDG uptake in these 17 patients without head and neck disease appear to reflect differences in activity of "physiological" inflammation of the palatine tonsils.	11545206
Inflammation	Altered Intercellular Communication	It is also possible that the increase in the number of B granules and the altered structures found among them in patients' epidermis express a reaction of L cells to inflammation.	11547473
Inflammation, Pyogenic granuloma	Altered Intercellular Communication	Pyogenic granulomas were found to occur at surgical and nonsurgical sites associated with tissue irritation or inflammation or both.	11548142
Doctor of Chiropractic, Inflammation, Myocarditis	Altered Intercellular Communication	Early survival in patients undergoing PLV for DCM is significantly affected by the degree of myocardial inflammation, so patients with more severe or ongoing inflammation may have poor clinical outcomes.	11548879
Airway structure	Altered Intercellular Communication	We conclude that eNO measurements are as useful as induced sputum analysis and AHR in assessing airway inflammation, with the advantage that they are easy to perform.	11549525
Airway structure, Asthma	Altered Intercellular Communication	These findings suggest that eosinophilic airway inflammation contributes to persistent airflow limitation in severe asthma.	11549526
Prader-Willi Syndrome	Altered Intercellular Communication	The cause of the reduced visceral adiposity in Prader-Willi syndrome may reflect novel hormonal, hypothalamic, and/or genetic influences on body fat distribution.	11549670
Craniopharyngioma, Precocious Puberty	Altered Intercellular Communication	Precocious puberty associated with growth hormone deficiency in a patient with craniopharyngioma: report of one case.	11550415
Communicable Diseases, Inflammation	Altered Intercellular Communication	The inability of NO to stop the infection may be caused by low sensitivity of the viruses to NO and/or by local low concentration of NO in the site of inflammation.	11550504
Inflammation, Lyme Disease	Altered Intercellular Communication	This report is about a rare connection between Lyme disease and an inflammation of the left temporomandibular joint.	11550610
Fibrinoid necrotizing inflammation	Altered Intercellular Communication	We investigated the role of cytokine receptor signals transduced into cells at the foci of rheumatoid inflammation.	11550959
Wheezing, Eosinophilic inflammation	Altered Intercellular Communication	Eosinophilic airways inflammation forms the pathophysiologic basis for a proportion of children at risk of developing recurrent wheezing.	11551254
palladium, Inflammation	Altered Intercellular Communication	We have shown that eosinophilic inflammation of the airway wall may increase PD and that the association of eosinophil counts with ICSs may result in lessening the PD.	11555508
Inflammation, Injury of larynx, Neoplasms, Unknown (origin) (qualifier value), Traumatic injury	Altered Intercellular Communication	The causes were neoplasm (29%), postoperative (24%), inflammation (21%), trauma from endotracheal intubation and external laryngeal trauma (8%), central (5%) and idiopathic causes (13%).	11556465
Melioidosis, Chronic inflammation, Malignant Neoplasms, Lupus Erythematosus	Altered Intercellular Communication	Another 59 patients (44.7%) had malignancies, 23 patients (17.4%) had miscellaneous other etiologies (including; 19 with chronic inflammations, 3 with melioidosis, and 1 with systemic lupus erythrematosus).	11556592
Inflammation, Hyperplastic Polyp, Hemorrhage	Altered Intercellular Communication	Routinely processed polypectomy specimens from 12 patients with 19 hyperplastic polyps containing foci of misplaced epithelium were evaluated for a variety of morphologic features including pattern and extent of submucosal involvement, continuity of the submucosal epithelium with the mucosa, presence of recent or remote hemorrhage, inflammation, association of misplaced epithelium with lymphoid aggregates, inflammation, and defects in the muscularis mucosae.	11557782
Granuloma, Inflammation	Altered Intercellular Communication	Needle track effect was defined as a combination of fibrohistiocytic reaction, fibrin clot, granuloma formation, and chronic inflammation.	11557788
Inflammation, Multiple Sclerosis	Altered Intercellular Communication	Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions.	11558796
Pain Distress Question, Inflammation, Nerve injury	Altered Intercellular Communication	The sodium channels SNS/PN3 and NaN/SNS2 are regulated by the neurotrophic factors-nerve growth factor (NGF) and glial-derived neurotrophic factor (GDNF), and may play an important role in the development of pain after nerve injury or inflammation.	11558987
Alzheimers Disease", Aggressive behavior, Data types - Address	Altered Intercellular Communication	Aggressive behavior in Alzheimer disease (AD) has been linked to dysfunction of serotonin neurotransmission.	11559314
Inflammation	Altered Intercellular Communication	It might be possible that corticosteroids could decrease inflammation of the joint, thus interfering with the correlations.	11560209
Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	We reviewed 60 cytologic samples, initially diagnosed as thoracic infection or inflammation among a total of 532 percutaneous transthoracic needle aspirations obtained from patients with clinical suspicion of malignancy in a period of 6 years.	11560219
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation was found in 12 samples (20.00%).	11560219
Inflammation, Appendicitis, CTCAE, Appendicitis Perforated, CTCAE	Altered Intercellular Communication	Clinical differences between perforated and non-perforated acute appendicitis could be explained by the presence of advanced inflammation in patients with perforated appendicitis.	11560388
Inflammation, Disease	Altered Intercellular Communication	"Uncontrolled inflammation" was defined as final disease activity above 1.5 or no improvement between initial and final activity.	11561793
Inflammation, Aortic Aneurysm	Altered Intercellular Communication	Furthermore, postoperative regression of perianeurysmal inflammation is rarely discussed in the few published accounts of endovascular repair of inflammatory aortic aneurysms.	11565044
Inflammation, Hydronephrosis	Altered Intercellular Communication	The case presented demonstrates successful endovascular treatment of an infrarenal inflammatory aneurysm with resolution of the retroperitoneal inflammation and hydronephrosis.	11565044
Inflammation, Fibrosis Assessment, Pain Distress Question	Altered Intercellular Communication	Inflammation in the subacromial bursa causes pain in patients suffering from rotator cuff tear, with this long-lasting inflammation leading to fibrosis and thickening of the subacromial bursa.	11565192
Rotator cuff syndrome, Inflammation	Altered Intercellular Communication	Both inflammatory cytokines and mechanical stress, and impingement in the subacromial space, might induce and worsen this inflammation.	11565192
Inflammation	Altered Intercellular Communication	Our findings suggest that those inflammatory cytokines and growth factors may play an important role in inflammation of the subacromial bursa.	11565192
Inflammation	Altered Intercellular Communication	The chronic inflammation that ensues involves the increased production of inflammatory cytokines.	11568511
Inflammation, Syndrome	Altered Intercellular Communication	We speculate that treatment with corticosteroids may decrease the influx of proinflammatory cytokines and neutrophil-induced inflammation, with resulting improvement in the outcome of cepacia syndrome in CF patients.	11568995
Enteric Nervous System, Gastrointestinal inflammation	Altered Intercellular Communication	Intestinal inflammation is associated with enteric nervous system alterations, at both inflamed and noninflamed sites.	11569680
Neoplasms, Colitis	Altered Intercellular Communication	Biological variability of fecal calprotectin in patients referred for colonoscopy without colonic inflammation or neoplasm.	11569695
Colonic Neoplasms, Inflammation	Altered Intercellular Communication	Fecal calprotectin concentration in stool has recently been proposed as a marker of colonic neoplasm and inflammation, but the intraindividual day-to-day variability has so far received little attention.	11569695
Neoplasms, Colitis	Altered Intercellular Communication	Day-to-day variation of fecal calprotectin is considerable in patients without colonic inflammation or neoplasm, for whom the pattern of stabile low fecal calprotectin may seem to be a valid negative predictor.	11569695
Inflammation	Altered Intercellular Communication	Autopsies in both cases showed inflammation involving the intermediolateral columns and the dorsal root ganglia.	11570600
Airway structure	Altered Intercellular Communication	However, it is unknown whether these drugs modulate airway inflammation after exposure to allergen in a natural setting.	11570617
Inflammation, Muscle fiber necrosis	Altered Intercellular Communication	All biopsies were marked by endomysial chronic inflammation, muscle fiber necrosis, and regeneration.	11570908
Inflammation, Angina, Unstable	Altered Intercellular Communication	Because plaque inflammation may modulate coronary vasomotion, the association between systemic levels of C-reactive protein (CRP) and coronary vasoreactivity was assessed in patients with stable or unstable angina.	11571238
Inflammation	Altered Intercellular Communication	Clinicians should consider the risk of inducing serious flares of hepatic inflammation due to abrupt nucleoside analogue withdrawal in these patients.	11573103
Inflammatory Bowel Diseases, Myocarditis, Hypersensitivity, Protein-Energy Malnutrition	Altered Intercellular Communication	Myocardial inflammation related to IBD may be due to a drug hypersensitivity reaction or micronutrient deficiency, or may be secondary to the underlying IBD as an extraintestinal manifestation.	11573104
Inflammatory abnormality of the eye	Altered Intercellular Communication	In addition syphilis has the ability to imitate any ocular inflammation.	11573160
Alzheimers Disease	Altered Intercellular Communication	The effectiveness of mirtazapine in depressed Alzheimer patents may be a reflection of its enhancement of brain serotonergic and noradrenergic neurotransmission.	11573849
Glucose Metabolism Disorders, Inflammation	Altered Intercellular Communication	The relation of markers of inflammation to the development of glucose disorders in the elderly: the Cardiovascular Health Study.	11574423
Glucose Metabolism Disorders, Inflammation	Altered Intercellular Communication	Several studies suggest that inflammation plays a role in the pathogenesis of some glucose disorders in adults.	11574423
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	There was no relationship between the development of diabetes and other markers of inflammation.	11574423
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Inflammation, as measured by CRP levels, is associated with the development of diabetes in the elderly.	11574423
Glucose Metabolism Disorders, Inflammation	Altered Intercellular Communication	Understanding the role of inflammation in the pathogenesis of glucose disorders in this age-group may lead to better classification and treatment of glucose disorders among them.	11574423
Inflammation	Altered Intercellular Communication	Reduction of corpus inflammatory activity correlated with changes in hysteresis (r = 0.604, p < 0.005), suggesting that the stomach attains it original shape faster when inflammation is reduced.	11575433
Tissue damage, Gastrointestinal inflammation	Altered Intercellular Communication	These findings indicate that eosinophils may contribute to tissue damage and intestinal inflammation in this disease.	11575456
Inflammation	Altered Intercellular Communication	Granulomatous inflammation of the breast is an inflammatory process with multiple etiologies.	11575665
Necrotizing granulomatous inflammation	Altered Intercellular Communication	This is the second fine needle aspiration (FNA) report of idiopathic granulomatous inflammation in the breast of a pregnant woman.	11575665
Granulomatous inflammation, Carcinoma	Altered Intercellular Communication	The diagnosis of granulomatous inflammation can be challenging, and the cytologic features can be difficult to separate from those of carcinoma.	11575665
Renal Insufficiency, Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	Impairment of renal and splanchnic perfusion during and after cardiopulmonary bypass may be responsible for acute renal failure and endotoxin-mediated systemic inflammation, respectively.	11576097
Uremia, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Although uremic and nonuremic groups share some of the risk factors for cardiovascular mortality, such as older age, diabetes, and inflammation, other factors appear to affect cardiovascular mortality in the opposite direction.	11576913
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Lymphoid aggregates, chronic mucosal inflammation with patchy activity, and the absence of epithelial mucus depletion were regular features of H heilmannii gastritis.	11577125
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Increasing evidence supports the involvement of inflammation in acute phase of coronary artery diseases.	11578706
vascular inflammations, Arterial Occlusive Diseases	Altered Intercellular Communication	Elevated levels of soluble (s) vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1, pointing to activation of cells involved in vascular inflammation, have been previously reported in peripheral arterial obstructive disease (PAOD).	11579367
Airway structure	Altered Intercellular Communication	To investigate the usefulness of expectorated sputum in the assessment of airway inflammation by smoking.	11579523
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	The goal of this study was to assess the presence of systemic inflammation in degenerative aortic valvular stenosis.	11583885
Inflammation, Atherosclerosis	Altered Intercellular Communication	It is presently unknown whether systemic signs of inflammation, similar to those observed in atherosclerosis, may be present in this disorder.	11583885
Inflammation, Aortic Valve Stenosis, Atherosclerosis	Altered Intercellular Communication	Systemic signs of inflammation, similar to those found in atherosclerosis, are present in patients with degenerative aortic valve stenosis.	11583885
Inflammation, Myositis, CTCAE 5.0	Altered Intercellular Communication	Our results indicate that MHC class II and MHC class I molecules may be involved in initiating and maintaining the pathological condition in myositis rather than only being a consequence of a preceding local inflammation.	11583954
Dislocation, complete, refracture	Altered Intercellular Communication	Two roots of group A and three roots of group B were extracted due to refracture, deterioration of periodontal inflammation, mobility, and luxation.	11585144
Inflammation, Inflammatory disorder, Human T-lymphotropic virus 1, MS gene	Altered Intercellular Communication	To clarify the immunopathological roles of Tc1 and Tc2 cells in central nervous system (CNS) inflammation, we examined intracellular cytokines in CD8+ and CD4+ T cells by flow cytometry and analyzed the Tc1/Tc2 balance as well as the Th1/Th2 balance in 80 patients with various CNS inflammatory diseases, including 20 with optico-spinal multiple sclerosis (OS-MS), 21 with conventional MS (C-MS), 22 with human T-lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and 17 with hyperIgEaemic myelitis.	11585633
Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Controlling these processes, rather than stopping inflammation, appears most important in preventing progressive disease and the fatal outcome common in IPF.	11587991
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide (eNO) is a rapid, sensitive method of assessing airway inflammation, and could be useful in this regard.	11587994
Airway structure, Airway Obstruction	Altered Intercellular Communication	Airway inflammation, present in 61% of the lung specimens, was not associated with reversible airway obstruction and did not correlate with the severity of airflow obstruction.	11587999
Uterine Cervical Neoplasm, Inflammation	Altered Intercellular Communication	An association of cervical inflammation with high-grade cervical neoplasia in women infected with oncogenic human papillomavirus (HPV).	11588127
Bacterial Vaginosis, Inflammation, Primary malignant neoplasm, cervical cancer	Altered Intercellular Communication	(Bethesda), 79: 23-30, 1987; C. J. Jones et al., Cancer Res., 50: 3657-3662, 1990), suggest a possible link between either genital tract inflammation or changes in bacteria flora consistent with bacterial vaginosis (BV) and cervical cancer.	11588127
Inflammation, Primary malignant neoplasm, Communicable Diseases, Squamous intraepithelial lesion, Lesion of cervix	Altered Intercellular Communication	To test whether changes in vaginal bacterial flora or the degree of cervical inflammation are associated with women having a human papillomavirus (HPV) infection or with women infected with oncogenic HPV having high-grade cervical lesions (high-grade squamous intraepithelial lesions or cancer), we conducted a case-control study of women <50 years old enrolled in the Costa Rican natural history study of HPV and cervical neoplasia.	11588127
Inflammation, Lesion of cervix	Altered Intercellular Communication	To test whether BV and inflammation were associated with high-grade lesions, Analysis 2 was restricted to women infected with oncogenic HPV, and the degree of inflammation and Nugent score were compared between women with (n = 95) and without (n = 158) high-grade cervical lesions.	11588127
Human papilloma virus infection, Inflammation	Altered Intercellular Communication	In Analysis 1, BV and cervical inflammation were not associated with HPV infection.	11588127
Inflammation	Altered Intercellular Communication	However, we found a marginally significant positive trend of increasing cervical inflammation associated with high-grade lesions in oncogenic HPV-infected women, (P(trend) = 0.05).	11588127
Uterine Cervicitis, Lesion of cervix	Altered Intercellular Communication	The results of this study suggest that cervical inflammation may be associated with high-grade lesions and may be a cofactor for high-grade cervical lesions in women infected with oncogenic HPV.	11588127
Infective corneal ulcer, Inflammation	Altered Intercellular Communication	Amniotic membrane transplantation seems to be a useful adjunctive surgical procedure for the management of infectious corneal ulcer by promoting wound healing and reducing inflammation.	11588424
Inflammation, Pterygium Of Conjunctiva And Cornea	Altered Intercellular Communication	We hypothesize that environmental stress, such as ultraviolet irradiation and local inflammation stimulate the elaboration of NO and VEGF, resulting in the conjunctival fibrovascular ingrowth characteristic of pterygium.	11588427
Inflammatory abnormality of the eye	Altered Intercellular Communication	The fornices were patent, there was no recurrence of symblepharon, ocular inflammation was suppressed, and the patient reported markedly increased comfort.	11588430
Pharyngitis	Altered Intercellular Communication	Efficacy and safety of ketoprofen lysine salt mouthwash versus benzydamine hydrochloride mouthwash in acute pharyngeal inflammation: a randomized, single-blind study.	11589263
Pharyngitis	Altered Intercellular Communication	The purpose of this study was to compare the efficacy and tolerability of mouthwash formulations of ketoprofen lysine salt (KLS), an anti-inflammatory agent, and benzydamine hydrochloride (BH), a local anesthetic, in patients with acute inflammation of the pharyngeal cavity.	11589263
Airway structure, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	Markers of airway inflammation and airway hyperresponsiveness in patients with well-controlled asthma.	11589340
Airway structure, Respiratory Hypersensitivity	Altered Intercellular Communication	In steroid-naive asthmatics, airway hyperresponsiveness correlates with noninvasive markers of airway inflammation.	11589340
Airway structure, Respiratory Hypersensitivity	Altered Intercellular Communication	Airway hyperresponsiveness in clinically well-controlled asthmatics appears to be independent of eosinophilic airway inflammation.	11589340
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation.	11589345
ARCN1 gene, Inflammation	Altered Intercellular Communication	Because pulmonary surfactant components play important roles in normal lung function, innate host defence, and inflammation in the lung, this study investigated the hypothesis that the surfactant protein genes are involved in certain cases of COPD.	11589345
Single organ dysfunction, Inflammation, Pancreatitis, Acute	Altered Intercellular Communication	Cellular markers of systemic inflammation and immune suppression in patients with organ failure due to severe acute pancreatitis.	11589386
Inflammation, Pancreatitis	Altered Intercellular Communication	Few data are available on cellular markers of systemic inflammation and immune suppression in early acute pancreatitis.	11589386
Inflammation, Gingival Hyperplasia	Altered Intercellular Communication	Gingival inflammation is a significant risk factor for gingival enlargement in these patients.	11589720
Presenile dementia, Inflammation	Altered Intercellular Communication	Inflammation has been involved in the pathogenesis of dementia.	11589916
Hepatosplenomegaly, Hepatic inflammation, airway disease, Niemann-Pick Diseases, Cholestasis	Altered Intercellular Communication	Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick disease, type C. Niemann-Pick disease, type C, was diagnosed in a 3-month-old boy with hepatosplenomegaly, mild signs of cholestasis, hepatic inflammation and extramedullary erythropoiesis, together with chronic airway disease.	11590212
AVP gene	Altered Intercellular Communication	A case of Rathke's Cleft Cyst inflammation presenting with diabetes insipidus.	11590900
AVP gene	Altered Intercellular Communication	Recently we experienced a case of RCC inflammation presenting with diabetes insipidus and treated with transsphenoidal surgery.	11590900
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis results from a T cell-driven inflammation in the synovial membrane that is frequently associated with the formation of tertiary lymphoid structures.	11591802
Inflammation	Altered Intercellular Communication	The central role of B cells in synovial inflammation identifies them as excellent targets for immunosuppressive therapy.	11591802
Intracapsular cataract extraction, Inflammation	Altered Intercellular Communication	Extracapsular cataract extraction and posterior chamber implantation seem to be well tolerated if inflammation is perfectly under control before surgery.	11591909
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To provide a comprehensive understanding of the humoral immune response that takes place at the site of inflammation in rheumatoid arthritis (RA), we studied the functional properties of synovial B cells.	11592364
Inflammation, Memory	Altered Intercellular Communication	Thus, T cell clonality at a site of inflammation may reflect enrichment for memory T cells specific for foreign antigens, rather than proliferation of autoreactive T cells specific for self antigens.	11592365
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Nitric oxide (NO) and prostaglandin E2 (PGE2) have been implicated as mediators of inflammation in OA.	11592370
Inflammation, Cholestasis	Altered Intercellular Communication	Cholestasis may be a model of short-term inflammation to study early alterations of steroidogenesis.	11592593
Inflammation, Portal inflammation	Altered Intercellular Communication	Centrilobular congestion, centrilobular necrosis, lobular inflammation and portal inflammation were not significantly related to survival.	11592594
Autoimmune Diseases, Inflammation, Musculoskeletal Pain	Altered Intercellular Communication	Mean characteristics of CC were: female predominance (91%), presence of extra-digestive manifestations (36%); mucosal inflammation with subepithelial collagen band and frequent association to rheumatic or autoimmune diseases suggest an immune basis for CC.	11593141
Rupture, Inflammation	Altered Intercellular Communication	Non-neoplastic, non-inflammatory cysts of the central nervous system may cause symptoms because of pressure, rupture or secondary inflammation.	11593239
Inflammation, Hereditary	Altered Intercellular Communication	The processes involved in the inflammation are determined by differently acquired and hereditary factors.	11595480
Inflammation	Altered Intercellular Communication	The incidence of melanomas with inflammation increased significantly (P = 0.04), as did age at diagnosis (P = 0.005).	11595879
Refractory Cytopenia of Childhood, Inflammation, Renal Cell Carcinoma Pathway	Altered Intercellular Communication	Evidence of systemic inflammation, i.e., elevation of serum C-reactive protein, interleukin-6, and/or the erythrocyte sedimentation rate, is correlated to poorer prognosis of patients with renal cell carcinoma (RCC).	11596022
Inflammation, Traumatic injury	Altered Intercellular Communication	For preventing such injuries, exact anatomical knowledge with its variants and a meticulous surgical dissecting technique especially in case of acute inflammation or shrunken gallbladder are mandatory.	11596898
Sarcoma, Inflammation	Altered Intercellular Communication	Sarcoma also had less prominent microvasculature, less variable cellularity, consistently > or =1 mitotic figure per 10 high-power fields, and predominant acute inflammation without plasma cells.	11598176
Infarction, Inflammation	Altered Intercellular Communication	Both inflammation and infarction may produce a similar clinical picture, including ST-segment elevation on the electrocardiogram.	11599821
Inflammation	Altered Intercellular Communication	Typically, inflammation affects the whole myocardium, resulting in characteristic electrocardiographic changes in all epicardial leads.	11599821
Chronic lymphocytic inflammation	Altered Intercellular Communication	Chronic lymphoplasmacytic inflammation affected 73% (mild or moderate in 97%).	11600333
Mesenteric Venous Thrombosis, Malignant Neoplasms, Liver Cirrhosis	Altered Intercellular Communication	Variables at diagnosis associated with reduced survival according to multivariate analysis were advanced age, malignancy, cirrhosis, mesenteric vein thrombosis, absence of abdominal inflammation, and serum levels of aminotransferase and albumin.	11600478
Fibrinoid necrotizing inflammation	Altered Intercellular Communication	T-cell responses to viral, bacterial and protozoan antigens in rheumatoid inflammation.	11600741
Inflammation, MS gene	Altered Intercellular Communication	Human endogenous retroviruses (HERVs) have been implicated as causative agents in diseases characterized by inflammation and macrophage activation, such as multiple sclerosis.	11601494
Bronchiectasis	Altered Intercellular Communication	Bronchiectasis is increasingly being recognized as an inflammatory condition of the airways in which pathological permanent dilation occurs.	11601743
Inflammation, Endothelial dysfunction, Diabetes Mellitus	Altered Intercellular Communication	Diabetic mellitus is attended by the development of endothelial dysfunction which is suggested to be accompanied with a chronic low-degree of inflammation.	11602810
Calculi	Altered Intercellular Communication	Parameters examined were oral hygiene, calculus, gingival inflammation/bleeding and periodontal pockets.	11602945
Granuloma, Inflammation	Altered Intercellular Communication	In inflammatory-related lesions such as eosinophilic granuloma, cessation of inflammation may be the mechanism of growth arrest, whilst temporary inflammation may stimulate osteogenic cells engaged in remodeling.	11603890
Neoplasms, Necrosis	Altered Intercellular Communication	Necrosis within the tumour and/or local changes in hormonal control, plus remodelling of the sclerotic area takes longer.	11603890
Inflammation, Traumatic injury	Altered Intercellular Communication	Initial laboratory studies were unremarkable, and radiographic studies showed free fluid in the pelvis with no evidence of solid organ injury, but inflammation of the right colon.	11604277
Inflammation, Hypersensitivity	Altered Intercellular Communication	The disease is a type III hypersensitivity reaction mediated by deposits of circulating immune complexes in small vessels, which leads to complement activation and subsequent inflammation.	11605816
Asthma, Obesity, Eosinophilic inflammation	Altered Intercellular Communication	The effects of increased BMI on asthma may be mediated by mechanical properties of the respiratory system associated with obesity or by upregulation of inflammatory mechanisms rather than by allergic eosinophilic inflammation of the airway epithelium.	11641506
Inflammation, Necrosis	Altered Intercellular Communication	Serum ALT levels were not positively correlated with total HAI score or HCV RNA titers, but showed a linear correlation with scores of piecemeal necrosis (r=0.32, p<0.05) and portal inflammation (r=0.27, p<0.05).	11641527
Inflammation	Altered Intercellular Communication	63 cases (67.0%) showed a chronic type and 23 cases (24.5%) showed a subacute type of inflammation.	11641805
Inflammation	Altered Intercellular Communication	However, there were no correlations between s-TfR level and markers of inflammation such as CRP, platelet count or RF titre.	11642510
Refractory anemias, Arthritis	Altered Intercellular Communication	In conclusion, s-TfR level in RA patients could be a marker of erythropoiesis rather than of joint inflammation.	11642510
Bronchial brand of guaifenesin-theophylline, Inflammation, Bronchiectasis, Injury of bronchus, Structure of respiratory epithelium, Carcinoma of lung, Bronchitis, Chronic	Altered Intercellular Communication	As a result, although our findings seem partly to confirm the hypothesis that local bronchial IgA secretion is impaired in areas of bronchial epithelial injury or inflammation, we thought that sIgA would be useless as a marker of respiratory epithelial injury or inflammation in patients with chronic bronchitis, bronchiectasis and lung cancer.	11642569
Urinary tract infection, Meningitis	Altered Intercellular Communication	We investigated the existence of concomitant meningeal inflammation in infants younger than 90 days old affected with UTI.	11642625
Meningitis	Altered Intercellular Communication	The pathogenesis of this meningeal inflammation is not fully understood.	11642625
Bacterial Infections, Urinary tract infection	Altered Intercellular Communication	Although bacterial infection of the subarachnoid space, with low bacterial seeding, cannot be excluded, at least in some cases, it is possible that CSF pleocytosis in some of the infants with UTI is mainly caused by the endotoxin of Gram-negative or other inflammation-inducing molecules of Gram-positive urine pathogens.	11642625
Inflammation	Altered Intercellular Communication	A differential expression of laminin isoforms is related to inflammation and subsequent IM caused by H. pylori.	11642721
Communicable Diseases, Chlamydia, Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Elevated levels of acute-phase proteins, a systemic marker for inflammation, predict coronary events; Chlamydia pneumoniae (C. pneumoniae) infection is associated with coronary atherosclerosis.	11665787
Communicable Diseases, Acute Coronary Syndrome, Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	The present study investigated whether inflammation or infection is involved in the pathogenesis of acute coronary syndrome (ACS) and which one has the more important role.	11665787
Heart failure, Congestive heart failure	Altered Intercellular Communication	Increased neurohormone and cytokine concentrations are associated with adverse outcome in patients with congestive heart failure, so minimizing these increases may improve outcome, even in the acute phase of decompensated heart failure.	11665788
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Inflammation and damage in an individual joint predict further damage in that joint in patients with early rheumatoid arthritis.	11665964
Arthritis, Erosion lesion	Altered Intercellular Communication	To further evaluate the roles of matrix metalloproteinase 1 (MMP-1), MMP-3, and tissue inhibitor of metalloproteinases 1 (TIMP-1) in the pathogenesis of joint inflammation and articular erosions in early inflammatory arthritis.	11665967
Arthritis, Joints	Altered Intercellular Communication	These data suggest an uncoupling of the pathophysiologic mechanisms associated with joint inflammation and articular erosion.	11665967
Inflammation, Abnormal umbilical cord, Umbilical granuloma	Altered Intercellular Communication	Umbilical granuloma (UG) is the most common umbilical abnormality in neonates, causing inflammation and drainage.	11666047
Eosinophilic disorder, Inflammation, Molecular Abnormality, Thyroid carcinoma	Altered Intercellular Communication	On the basis of the cytogenetic and molecular abnormality, the patient was diagnosed as having CEL, rather than reactive eosinophilia due to thyroid or prostatic cancer or other reactive inflammation.	11669308
Inflammation	Altered Intercellular Communication	Thus, cell-surface proteoglycan expression by lymphocytes in periodontal inflammation is cell-type-specific and may be modulated by inflammation.	11669479
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Blood cell activation, coagulation, and inflammation in men and women with coronary artery disease.	11672587
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Plasma markers of coagulation and inflammation were analyzed.	11672587
Acute Coronary Syndrome, Observation Method - Coagulation, Inflammation	Altered Intercellular Communication	We conclude that in unstable coronary syndromes, there is an activation of both coagulation and inflammation that coincides with an increased activation of platelets and leukocytes.	11672587
Vitreous inflammatory cells, Uveitis	Altered Intercellular Communication	There was a significant correlation between MIF levels and vitreous inflammation (29.7 (30.0) ng/ml in active uveitis v 3.3 (2.6) ng/ml in inactive uveitis, p< 0.05).	11673308
Vitreous inflammatory cells	Altered Intercellular Communication	MIF levels in vitreous fluid are correlated with vitreous inflammation activity.	11673308
Inflammatory abnormality of the eye	Altered Intercellular Communication	These data thus indicate that MIF in the eye has a significant role in the pathophysiology of ocular inflammation.	11673308
Inflammation, Trauma, Nervous System, Cerebrovascular accident	Altered Intercellular Communication	There has been recent interest in the possible role of reperfusion-induced inflammation with neuronal injury after stroke.	11673584
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Chronic, subclinical inflammation may be one pathophysiological mechanism explaining the increased risk of atherosclerotic disease associated with adiposity.	11673759
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Our study has shown an independent relationship of central fat accumulation and insulin resistance with CRP plasma levels, thus suggesting that mild, chronic inflammation may be a further component of the metabolic syndrome and a mediator of the atherogenic profile of this syndrome.	11673760
Sepsis, Inflammation	Altered Intercellular Communication	Patients with sepsis markedly increased their output of o,o'-dityrosine into urine, suggesting that systemic inflammation also may be a potent source of oxidative stress in humans.	11673867
Uremia, Inflammation, Liver Cirrhosis	Altered Intercellular Communication	Protease levels were also low in patients with cirrhosis, uremia, and acute inflammation, and they fell in the postoperative period.	11675345
Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	Proposed mechanisms include inhibition of epithelial cell growth resulting in ulceration and inflammation of the gut mucosa, inhibition of glycoprotein synthesis affecting the integrity of the mucosal wall, and stimulation of kiler T cells, leading to epithelial cell injury and a resultant inflammatory response.	11675849
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	These findings suggest that natural killer cells are increased in active ulcerative colitis subjects and that the affected mucosa of ulcerative colitis patients with inactive disease is in state of "latent" inflammation.	11677954
Inflammation, Liver carcinoma	Altered Intercellular Communication	After partial hepatectomy, a pathological examination revealed well to moderately differentiated hepatocellular carcinoma with only mild chronic inflammation in adjacent liver tissue.	11677984
Granulomatous inflammation	Altered Intercellular Communication	Synovectomy was performed and histopathologic examination of the surgical specimen revealed granulomatous inflammation with caseation, prominent Langhan's giant cells, and sparse acid-fast bacilli.	11678011
Airway structure, Acute asthma	Altered Intercellular Communication	The involvement of matrix metalloproteinase-9 in airway inflammation of patients with acute asthma.	11678864
Airway structure, Asthma	Altered Intercellular Communication	These data suggest that airway inflammation after asthma exacerbation correlates with the overproduction of MMP-9, which then leads to airway remodelling.	11678864
Inflammation, Granulomatosis with polyangiitis	Altered Intercellular Communication	Recently, the predominance of the Th1 cytokine pattern has been directly observed in the granulomatous inflammation of patients with Wegener's granulomatosis.	11678911
Inflammation	Altered Intercellular Communication	Previous studies have suggested a common occurrence of inflammation and inflammatory cells, particularly macrophages, in DHs.	11679814
Inflammation, Abscess	Altered Intercellular Communication	Loss of height and peridiscal inflammation at L3-L4 and epidural and bilateral psoas abscesses were detected.	11679828
Compact Disk Interactive, Hormone abnormality	Altered Intercellular Communication	CDI is a complicated hormonal disorder characterized by excessive urine output.	11679837
ACSM3 gene, Inflammation	Altered Intercellular Communication	The present results suggest that leukocytes induced by SAH play an important role in post-hemorrhagic inflammation in the subarachnoid space by releasing IL-6 and TGF-beta1.	11680512
palladium, Inflammation	Altered Intercellular Communication	Although several factors may contribute to changes in peritoneal transport rate, inflammation is known to be associated with a high peritoneal transport rate, and residual renal function (RRF), which often declines after start of PD, may also be related to inflammation.	11682675
palladium, Inflammation	Altered Intercellular Communication	Therefore, we hypothesized that changes in peritoneal transport rate during patients' first year on PD and declining RRF may be linked with inflammation.	11682675
palladium, Inflammation	Altered Intercellular Communication	Our preliminary short-term study suggests that changes in peritoneal transport rate during patients' first year on PD may be linked with inflammation and declining residual renal function.	11682675
palladium, Inflammation	Altered Intercellular Communication	Inflammation and residual renal function were identified as the only independent factors determining peritoneal transport rate during the first year on PD.	11682675
Acute and chronic inflammation	Altered Intercellular Communication	Within the Hp-gastritis group, serum pepsinogen I and II levels were correlated with antral chronic inflammation score and serum pepsinogen II levels also with antral activity score.	11683924
Inflammation, Gastritis, Atrophy of corpus callosum	Altered Intercellular Communication	In dyspeptic patients known to be infected with H. pylori, serum pepsinogen values provide an assessment of the overall topography of gastritis, the severity of antral inflammation and the presence of severe corpus atrophy.	11683924
Inflammation, Endothelial dysfunction, Congestive heart failure	Altered Intercellular Communication	Systemic inflammation and increased oxidative stress in congestive heart failure (CHF) coincide with enhanced EC apoptosis and the development of endothelial dysfunction.	11684628
Gastrointestinal Stromal Tumors, Inflammation	Altered Intercellular Communication	Only one of the two appendices operated for symptoms had acute inflammation, and a polypoid GIST projected outward from the proximal part of appendix.	11684962
Inflammation, Intraocular inflammation	Altered Intercellular Communication	Clinicopathologic evaluation revealed acute inflammation of the corneal remains as well as intraocular inflammation.	11685075
Necrotizing Scleritis	Altered Intercellular Communication	Eleven patients with necrotizing scleritis treated with systemic immunosuppressors received transeptal corticosteroid injections during periods of active inflammation.	11685675
Inflammation, Scleritis	Altered Intercellular Communication	Systemic immunosuppressors remain as the first choice treatment for necrotizing scleritis; however, transeptal corticosteroid injections may be helpful as additional treatment during periods of active inflammation.	11685675
Autoimmune Diseases, Inflammation, polychondritis	Altered Intercellular Communication	We report a case of a 22-year-old woman with relapsing polychondritis (RP)--a rare and little known systemic autoimmune disease characterised by episodic inflammation of cartilaginous structures (ear, nose, bronchi, trachea, larynx, ribs, cardiovascular system).	11685960
Inflammation, Myocardial Ischemia, Atherosclerosis	Altered Intercellular Communication	Increasing evidence has indicated the important roles of inflammation and immune response in the development of atherosclerosis and ischemic heart disease (IHD).	11686313
Inflammation, Asthma	Altered Intercellular Communication	It is important to monitor inflammation regularly in asthma in addition to clinical symptoms, and there is a great need for noninvasive tests that could routinely be used in clinical practice.	11686425
Inflammation, Neoplasms	Altered Intercellular Communication	Tenascin-C is a multifunctional matrix protein that is induced in inflammation and neoplasia.	11686525
Inflammation, Periodontal Route of Administration	Altered Intercellular Communication	Most people had clinical attachment loss but despite poor oral hygiene and extensive gingival inflammation, they did not have very severe periodontal destruction.	11686819
Parkinson Disease, Emotionality	Altered Intercellular Communication	The correlation between the personality trait of harm avoidance and (18)F-dopa may reflect a specific feedback circuitry of neurotransmitters that is associated with negative emotionality in Parkinson's disease.	11687621
Miller Dieker syndrome, Acute inflammation, Vasculitis, CTCAE, Behcet Syndrome	Altered Intercellular Communication	Some cases of Behcet's syndrome and MDS have been reported in association with trisomy 8 and HLA B51, with the pathology varying from vasculitis to acute neutrophilic inflammation.	11687870
Inflammation	Altered Intercellular Communication	This finding was almost always accompanied by mixed chronic inflammation in the lamina propria and by surface epithelial damage of varying severity.	11688577
Inflammation, Acute Coronary Syndrome, Atherosclerosis	Altered Intercellular Communication	Inflammation plays an important role in the pathogenesis of atherosclerosis and acute coronary syndromes.	11689215
Pneumonitis	Altered Intercellular Communication	Additional experiments were also conducted in which AMs were primed with lipopolysaccharides (LPS) to simulate preexisting pulmonary inflammation such as that which might exist in sick and elderly individuals.	11689347
Inflammation, Toxic effect	Altered Intercellular Communication	TNF releases were further amplified for primed AMs, suggesting that preexisting inflammation can potentially exacerbate the toxicity of not only outdoor PM(2.5) (as shown by previous studies) but also indoor PM(2.5).	11689347
Chronic liver disease, Inflammation, Hepatocarcinogenesis	Altered Intercellular Communication	These results indicate that oxidative DNA damage is common in various forms of chronic liver disease suggesting a possible link between chronic inflammation and hepatocarcinogenesis.	11690707
Inflammation, Carotid Intima-Media Thickness	Altered Intercellular Communication	Increased common carotid intima-media thickness in UK African Caribbeans and its relation to chronic inflammation and vascular candidate gene polymorphisms.	11692002
Communicable Diseases, Inflammation	Altered Intercellular Communication	We measured carotid IMT in UK African Caribbeans compared with UK whites and determined whether different distributions of polymorphisms in potential candidate vascular genes or differences in measures of chronic inflammation or infection could account for any difference.	11692002
Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The causative association between Helicobacter pylori and gastric mucosal inflammation is well established.	11692066
Urethritis, Urethra	Altered Intercellular Communication	The etiology include 14 patients after perineal urethral trauma, in 10 patients the main cause was urethral inflammation of posterior urethra, in 8--as a consequence of transurethal surgery and in 5--after suprapubic prostatectomy.	11692934
Inflammatory disorder	Altered Intercellular Communication	These data were compared with age-matched healthy and the disease control groups of chronic noninflammatory GI diseases (cGI), acute noninflammatory GI diseases (aGI), and chronic non-GI inflammation (non-GI).	11693331
Inflammation	Altered Intercellular Communication	Persistent or distorted activation of blood DC or divergent regulation of costimulatory and activation antigens may have important implications for gut mucosal immunity and inflammation.	11693331
Inflammation, polychondritis	Altered Intercellular Communication	Relapsing Polychondritis is a rare disease which causes the repetitive inflammation of cartilage and connective tissues.	11693668
Inflammation	Altered Intercellular Communication	Low-grade inflammation as evidenced by elevated preprocedural serum CRP-levels is an independent predictor of adverse outcome after coronary stent implantation, suggesting that a systemically detectable inflammatory activity is associated with proliferative responses within successfully implanted stents.	11693760
Inflammation, Perforation (observation), Neoplasms, Specimen Type - Fistula, Ulceration, CTCAE	Altered Intercellular Communication	It is sometimes associated with complications related to the presence of ectopic tissue (obstruction, ulceration, hemmorhage, inflammation, perforation, fistula and tumors).	11693808
Inflammation, SLC22A5 gene, Pain Distress Question	Altered Intercellular Communication	Purified poloxamer 188 may increase tissue oxygenation and thereby reduce inflammation, pain, and the overall duration of such painful episodes in patients with SCD.	11694150
Inflammation, Neoplasms	Altered Intercellular Communication	Such method allows, precociously, to put in evidence a possible presence of inflammation, induced by any kind of tumor, even in absence of positiveness of the specific tumoral markers, in 38% of examined cases.	11695302
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Our results suggest the involvement of TNF-alpha in mechanisms of early stroke-induced inflammation and a predictive value of the initial TNF-alpha levels for the outcome of stroke.	11696023
Airway structure, Asthma	Altered Intercellular Communication	Sputum induction is a safe and effective technique to study airway inflammation in stable asthma.	11696051
Communicable Diseases, Inflammation	Altered Intercellular Communication	The chemotactic cytokine interleukin-8 (IL-8) plays an important role in attraction and activation of polymorphonuclear leukocytes in infection and inflammation.	11696635
Pain Distress Question, Neurogenic Inflammation	Altered Intercellular Communication	The rationale was based on the hypothesis that pelvic floor myofascial trigger points are not only a source of pain and voiding symptoms, but also a trigger for neurogenic bladder inflammation via antidromic reflexes.	11696740
Inflammation	Altered Intercellular Communication	Comparison of microscopic methods for detecting inflammation in expressed prostatic secretions.	11696821
Inflammation	Altered Intercellular Communication	Of 159 initial patient evaluations 84 (53%) showed inflammation by hemocytometer concentration at 500 leukocytes per mm.3 or greater but only 37 (23%) were considered inflammation by the traditional wet mount method (p <0.001).	11696821
Inflammation	Altered Intercellular Communication	Inflammation was identified in 149 of 251 specimens (59%) by hemocytometer but in only 82 (33%) by wet mount (p <0.001).	11696821
Inflammation	Altered Intercellular Communication	When inflammation was defined as 1,000 leukocytes per mm.3 or greater the hemocytometer still identified significantly more patients (41%) and specimens (48%) with inflammation than the wet mount.	11696821
Inflammation	Altered Intercellular Communication	Significantly more cases of inflammation were detected by hemocytometer than by the traditional wet mount technique.	11696821
prostatitis	Altered Intercellular Communication	These findings support the adoption of hemocytometer and staining methods for accurate evaluation of expressed prostatic secretion inflammation in men with chronic prostatitis/chronic pelvic pain syndrome.	11696821
Inflammation, Tissue Adhesions	Altered Intercellular Communication	Often, previous attempts at treatment with shockwave lithotripsy or endourologic procedures also lead to inflammation and adhesions, making surgery difficult.	11697400
HD Term Type, Inflammation, Liver Dysfunction	Altered Intercellular Communication	In conclusion, increased plasma FBG level, a continuum between liver dysfunction and stimulation by chronic inflammation, is an important determinant of prolonged ECLT in HD patients.	11697712
Airway structure, Asthma	Altered Intercellular Communication	In addition, symptoms of lower airway inflammation did improve significantly in asthmatic patients.	11700449
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The involvement of tryptase- and VIP-positive mast cells in inflammation, fibrosis and epithelial reactions in the common bile duct is discussed.	11700949
Disturbance	Altered Intercellular Communication	Alternatively, changes in secretion of neurohormones in the periphery might contribute to the central disturbance.	11701596
Inflammation, Demyelination, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	Altered Intercellular Communication	The objective of the study was to determine the diagnostic value of features of demyelination and inflammation in sural nerve biopsy specimens of patients with chronic inflammatory demyelinating polyneuropathy (CIDP).	11701597
Axonal degeneration, Demyelination, Inflammation, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	Altered Intercellular Communication	Although significant differences of features of demyelination, axonal degeneration and inflammation were found in sural nerve biopsy specimens, there was a considerable overlap between abnormalities in CIDP and CIAP patients.	11701597
Acute inflammation	Altered Intercellular Communication	Acute bowel inflammation frequently originates from thin-walled diverticula of the colon.	11702128
Inflammation, Diverticulitis, Diverticulum, cell wall thickening	Altered Intercellular Communication	Not the presence of diverticula, but the demonstration of an inflamed diverticulum, is diagnostic of diverticulitis in cases of bowel wall thickening and pericolic inflammation.	11702128
Inflammation, Diverticulum	Altered Intercellular Communication	Outpouchings from the colonic wall centred in the pericolic inflammation were considered inflamed diverticula.	11702128
Acute inflammation	Altered Intercellular Communication	Operative and post-operative complications, degree of postoperative inflammation, best-corrected and final visual acuity were the main outcome measures.	11702974
Allergic, Inflammation	Altered Intercellular Communication	It is noteworthy that allergic subjects display higher levels of nasal ECP and tryptase than healthy subjects, even when symptom-free, and these observations may indicate the presence of subclinical inflammation.	11703225
Uremia, Inflammation, Hyperhomocysteinemia	Altered Intercellular Communication	Inflammation, not hyperhomocysteinemia, is related to oxidative stress and hemostatic and endothelial dysfunction in uremia.	11703602
Cancer-related fatigue, Inflammation, Hyperhomocysteinemia, Chronic Kidney Diseases	Altered Intercellular Communication	Several cardiovascular risk factors are present in patients with chronic renal failure (CRF), among which are systemic inflammation and hyperhomocysteinemia.	11703602
Cancer-related fatigue, Inflammation, Impaired T cell function	Altered Intercellular Communication	Systemic inflammation, which is closely associated with augmented oxidative stress, endothelial cell dysfunction and hemostatic activation, emerges as a major cardiovascular risk factor in CRF.	11703602
allergic inflammation	Altered Intercellular Communication	IL-4 and IL-13 are important in IgE synthesis and allergic inflammation.	11704288
ARCN1 gene, Inflammation, Weight decreased, Muscle (organ)	Altered Intercellular Communication	Skeletal muscle loss in COPD is probably multifactorial in origin, but our data suggest a link with systemic inflammation, even when weight loss is inapparent.	11704588
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation and alterations in cellular turnover are histopathologic features of asthma.	11704601
Gastrointestinal inflammation	Altered Intercellular Communication	Nonsteroidal anti-inflammatory drug (NSAID) usage is associated with gastrointestinal inflammatory damage and aggravation of gut inflammatory conditions.	11704643
allergic inflammation	Altered Intercellular Communication	Interleukin-12 (IL-12) is a macrophage-derived cytokine that modulates T lymphocyte responses and can suppress allergic inflammation.	11704807
Constipation, Inflammation	Altered Intercellular Communication	Furthermore, pathological findings included constipation in one child and inflammation of the ileo-colic and mesenterial lymph nodes were found in another child.	11704907
Rupture, Inflammation, Neoplasms, Esophageal Perforation, Mediastinal pleura, Esophageal Diseases	Altered Intercellular Communication	The result in the management of esophageal perforation is influenced by several factors: localization and size of the rupture, length of delay in diagnosis, age, extent of mediastinal and pleural contamination, the presence of underlying esophageal diseases, and inflammation or tumor at the perforation localization.	11705168
Inflammation	Altered Intercellular Communication	As no other causes for the inflammation were found, the optic nerve involvement must have been caused by the vaccination.	11706386
Inflammation	Altered Intercellular Communication	It suggests that slowly expanding lesions (progressive plaques), in which ongoing myelin breakdown occurs in the absence of florid perivascular cell cuffing or other histological signs of acute inflammation, contribute to disease progression in cases of secondary-progressive multiple sclerosis.	11706971
Retinal Detachment, Inflammation, Traumatic injury, Edema	Altered Intercellular Communication	Postoperative complications included transient hypotony in 2 eyes, mild persistent inflammation in 1 eye, and macular edema followed by a retinal detachment in 1 eye with recent severe trauma.	11709244
Nonestrogen-Dependent Malignant Neoplasm, Pancreatic carcinoma	Altered Intercellular Communication	Our data support the hypothesis that pancreatic cancer is, at least in part, an estrogen-dependent disease; there is growing epidemiological evidence that aspects of reproductive history and hormonal exposure are associated with risk of this disease.	11709276
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	In contrast, the gastric type CK7/CK20 pattern was linked to atrophic (p<0.02) or erythematous (p<0.05) appearance of the stomach (p<0.03), high frequency of H pylori infection (p<0.04), antral inflammation (p<0.006) with atrophy (p<0.02), and intestinal metaplasia (p<0.02).	11709508
Pain Distress Question, Nerve injury	Altered Intercellular Communication	Nerve signals arising from sites of tissue or nerve injury lead to long term changes in the central nervous system and the amplification and persistence of pain.	11709938
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Relationships of matrix metalloproteinases and their inhibitors to cartilage proteoglycan and collagen turnover and inflammation as revealed by analyses of synovial fluids from patients with rheumatoid arthritis.	11710706
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To determine interrelationships in matrix turnover in articular cartilage and joint inflammation in rheumatoid arthritis (RA).	11710706
Refractory anemias, Inflammation, destruction joint, Pannus	Altered Intercellular Communication	Once expressed, VEGF likely plays a crucial role in the neovascularization of the pannus and the progressive joint destruction associated with the synovial inflammation of RA.	11710707
Osteomyelitis, Inflammation, Cellulitis	Altered Intercellular Communication	The difference in indices between 3P-MDP and 4P-MDP for osteomyelitis and indices for osteomyelitis, cellulitis, and inflammation in Tc-99m HIG and Tc-99m WBC in early and late scans were tested for significance.	11711704
Osteomyelitis, Inflammation, Cellulitis	Altered Intercellular Communication	Among these 53 lesions were 25 sites of proved osteomyelitis, 6 sites of cellulitis, and 22 sites of inflammation confirmed by radiography, microbiologic culture, and clinical evaluation.	11711704
Osteomyelitis, Inflammation, Cellulitis	Altered Intercellular Communication	There was no significant difference between the indices of early and late Tc-99m HIG scans for inflammation, cellulitis, and osteomyelitis.	11711704
Communicable Diseases, Inflammation	Altered Intercellular Communication	However, Tc-99m WBC scans could differentiate aseptic inflammation from infection (P < 0.031) in early and late scans.	11711704
Shock, Inflammation, Behcet Syndrome	Altered Intercellular Communication	Heat shock protein (60 kd HSP) has been implicated in the etiology of Behcet's disease, but its expression at sites of inflammation is unknown.	11712037
Inflammation	Altered Intercellular Communication	Laboratory data on her admission demonstrated apparent signs of inflammation and she was soon undergone an emergency operation.	11712365
Coronary heart disease	Altered Intercellular Communication	The levels of bilirubin may be related to an inflammatory condition in patients with coronary heart disease.	11712741
Lupus Erythematosus, Systemic	Altered Intercellular Communication	sFas levels seems to be secondary to alfa-TNF action, which is enhanced in inflammatory conditions such as SLE.	11712810
Inflammation	Altered Intercellular Communication	Sixty-five percent of specimens demonstrated chronic inflammation.	11713075
Inflammation	Altered Intercellular Communication	Three independent observers scored the images into categories of no (1), mild (2), moderate (3) or severe (4) inflammation.	11713375
Inflammation	Altered Intercellular Communication	No patient classified as having no (1) inflammation was given a score of moderate (3) or severe (4) inflammation and vice versa.	11713375
Inflammation, Chagas Disease, Leucocytic infiltrate	Altered Intercellular Communication	While Chagas' disease was associated with severe inflammation and poor survival, the presence of inflammatory cell infiltration had no effect on survival in all patients combined (p = 0.943).	11713859
Inflammation	Altered Intercellular Communication	Improved pharmacological products for suppressing inflammation will lead to increasing demands on out-patient rheumatological care.	11715248
Inflammation, Myocardial Infarction	Altered Intercellular Communication	No perioperative myocardial infarctions and no signs of inflammation were observed.	11717016
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	One case died of lung metastasis, two cases died of inflammation of lungs.	11717878
Inflammation	Altered Intercellular Communication	The vascular leucocyte adhesion molecule, L-selectin, plays an important early role in monocyte trafficking at sites of inflammation, a process which leads to the development of inflammatory organ failure.	11718969
Inflammation, Asthma	Altered Intercellular Communication	The airways of individuals with asthma are less distensible than normal and it has been assumed that this may be due to airway remodeling associated with chronic inflammation, although there are currently no available data directly relating these two aspects of asthma.	11719315
Inflammation, Diverticulitis, Pelvic peritonitis, Periappendicitis	Altered Intercellular Communication	There were 28 true-positive cases; two false-positive cases, one cecal diverticulitis and one pelvic peritonitis with periappendicitis; and two false-negative cases, one perforated appendix and one mucosal and submucosal inflammation of the appendix but no transmural inflammation.	11719671
Inflammation	Altered Intercellular Communication	The selective expression of CXCR3+ cells in the submucosa of CD patients might also indicate that these cells play a role in inflammation.	11720316
Tumor necrosis, Coronary Arteriosclerosis, Hypopituitarism	Altered Intercellular Communication	The adipocyte products, leptin and tumour necrosis factor (TNF)alpha, are associated with atherosclerotic diseases and may be factors contributing to the enhanced cardiovascular risk in hypopituitary patients with growth hormone (GH) deficiency.	11720898
Fibrous, Inflammation	Altered Intercellular Communication	Needle biopsy revealed only fibrous tissue with signs of chronic inflammation.	11721119
HD Term Type, Inflammation	Altered Intercellular Communication	The Hct-corrected ESR values of 23 and 59 mm/h precisely select the HD patients with severe inflammation from those without.	11721153
Inflammation	Altered Intercellular Communication	Chronic inflammation in the ileal pouch is the most significant late complication after ileal pouch-anal anastomosis (IPAA).	11721757
Inflammation, Pouchitis, Villous atrophy	Altered Intercellular Communication	Metabolic consequences after IPAA are associated with pouchitis, grade of villous atrophy, and extent of inflammation in the remaining ileum.	11721757
Inflammation, Malaria, Anemia	Altered Intercellular Communication	Children with malaria had higher serum transferrin receptor concentrations than expected for the degree of anemia, even after adjustment for inflammation indicated by serum C-reactive protein concentration quartiles (P = 0.02).	11722958
Hypophysitis, CTCAE, Infundibulo neurohypophysitis	Altered Intercellular Communication	Infundibulohypophysitis is an unusual inflammatory condition that affects the infundibulum, the pituitary stalk, and the neurohypophysis and may be part of a range that includes lymphocytic hypophysitis.	11723207
Inflammation, Sepsis, Critical Illness, Traumatic injury, Shock	Altered Intercellular Communication	Ratio of neutrophil to lymphocyte counts--rapid and simple parameter of systemic inflammation and stress in critically ill. For many years, the intensivists are searching for an easily measurable and available parameter which might reflect the intensity of stress and/or systemic inflammation in critically ill patients following shock, multiple trauma, major surgery or sepsis.	11723675
Sepsis, Inflammation	Altered Intercellular Communication	In the population of 90 ICU oncological patients, we observed rapid serial changes in white blood cell populations, as a response of the immune system to surgical stress, systemic inflammation or sepsis.	11723675
Inflammation, Osteomyelitis of vertebra	Altered Intercellular Communication	This case report suggests that it is important for complementary antibiotic therapy to continue after signs of inflammation have disappeared in cases of pyogenic vertebral osteomyelitis.	11725834
Inflammation, Traumatic injury	Altered Intercellular Communication	Severe trauma acts as a trigger for the complex cascade of postinjury events leading to the release of different mediators and the development of generalized inflammation.	11726035
Inflammation, Squamous metaplasia	Altered Intercellular Communication	Mild inflammation and squamous metaplasia were also noted.	11726116
Inflammation, Ocular Toxoplasmosis	Altered Intercellular Communication	The functional characteristics of the VF-derived Tg-specific T cells and their presence at the site of inflammation suggest their involvement in the local inflammatory response of ocular toxoplasmosis.	11726627
Calcification of mitral valve, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Drugs that modulate inflammation in endo- and pericardial tissue may, at least in part, be responsible for the observed mitral valve calcifications and pericardial fibrosis.	11727842
Inflammation, Coronary heart disease	Altered Intercellular Communication	Inflammation is a key component of coronary heart disease, and genes coding for cytokines are candidates for predisposing to coronary heart disease risk.	11728144
Malnutrition	Altered Intercellular Communication	Malnutrition inflammation complex syndrome (MICS) occurs commonly in maintenance hemodialysis (MHD) patients and may correlate with increased morbidity and mortality.	11728958
Inflammation, Anemia	Altered Intercellular Communication	The MIS appears to be a comprehensive scoring system with significant associations with prospective hospitalization and mortality, as well as measures of nutrition, inflammation, and anemia in MHD patients.	11728958
Granulomatous inflammation	Altered Intercellular Communication	Histopathological examination, however, showed granulomatous inflammation with eosinophils suggesting extraintestinal CD.	11730049
Epistaxis, Granulomatosis with polyangiitis, Vasculitis, CTCAE, Conjunctivitis, Congestion of nasal sinus	Altered Intercellular Communication	An 80-year-old man presented with chronic cicatrizing conjunctivitis, peripheral corneal thinning, and Wegener granulomatosis, which were diagnosed by his referring physician based on clinical (recurrent epistaxis, sinus congestion) and histopathologic features of nasal mucosa (granulomatous inflammation, vasculitis).	11730661
Inflammation, Granulomatosis with polyangiitis	Altered Intercellular Communication	Careful observation is necessary in eyes with persistent inflammation in Wegener granulomatosis.	11730662
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Thus, inflammation in the lung may contribute to high levels of manganese SOD and decreased catalase, which together may lead to increased hydrogen peroxide intracellularly and create an intracellular environment favorable to DNA damage and the promotion of cancer.	11731445
Inflammation, Atrophic iris, Disorder of the optic nerve, Lens dislocation, Cataract, Ophthalmoplegia	Altered Intercellular Communication	Bee stings of the cornea are very rare, though its response can range from minimal inflammation to severe damage like lens dislocation, cataract formation, iris atrophy, ophthalmoplegia and optic neuropathy.	11731905
Whipple Disease, Inflammatory abnormality of the eye	Altered Intercellular Communication	We report results of one more polymerase chain reaction (PCR) analysis-diagnosed ocular Whipple's disease (OWD) case and the care of three new patients with ocular inflammation caused by OWD.	11733263
Inflammatory abnormality of the eye	Altered Intercellular Communication	Response of ocular inflammation and vision to treatment.	11733263
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Different pathologic stages correlating to duration of symptoms were found ranging from active chronic inflammation to proliferative sclerotic forms and total subepithelial fibrosis.	11733281
Inflammation, Hyperemia	Altered Intercellular Communication	Descending inflammation from the eye or ascending inflammation from the nose initiates swelling of the mucous membrane, remodeling of the helical arrangement of connective tissue fibers, malfunctions in the subepithelial cavernous body with reactive hyperemia, and temporary occlusion of the lacrimal passage.	11733281
Inflammation, Thickened	Altered Intercellular Communication	Histopathologic examination of the intestines of the 1:200 and 1:400 meconium groups showed serosal thickening, inflammation, focal fibrin, and collagen deposits.	11733912
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Surprisingly, in IBD CD44v6 was downregulated on CD4(+) lamina propria T cells, irrespective of their state of inflammation (median, 28%).	11733944
Inflammation	Altered Intercellular Communication	Bronchoalveolar cytology showed increased (30%) lymphocyte counts and bronchial biopsy revealed thickening of basal membrane and active chronic inflammation.	11734067
Chronic progressive external ophthalmoplegia, External Ophthalmoplegia, Orbital Pseudotumor, Ophthalmoplegia, Myasthenia Gravis	Altered Intercellular Communication	The aetiology of ophthalmoplegia was myasthenia gravis (MG; n=2), chronic progressive external ophthalmoplegia (CPEO; n=2), and chronic idiopathic orbital inflammation.	11734519
Pneumonitis, CTCAE, Pneumonitis	Altered Intercellular Communication	However, combining these therapies may increase the incidence of radiation pneumonitis, a lung inflammation.	11734597
Cataract, Inflammation	Altered Intercellular Communication	Several specific postoperative complications of trabeculectomy were associated with increased risk of cataract, particularly marked inflammation (RR = 3.29; P<.001) and flat anterior chamber (RR = 1.80; P =.004).	11735786
Inflammation, Subacute Bacterial Endocarditis	Altered Intercellular Communication	Streptococcal subacute endocarditis is characterized by low-grade systemic inflammation.	11737229
Inflammation, Infection, Ulcer	Altered Intercellular Communication	Recurrent infections, inflammation, and ulcers can lead to significant chronic morbidity.	11737691
Inflammation, Chronic infectious disease, Chlamydia, Plaque, Atherosclerotic, atherosclerotic	Altered Intercellular Communication	To determine whether chronic infection with Chlamydia pneumoniae, which has been identified in atherosclerotic plaques, is responsible for systemic inflammation, we studied the association between serum C-reactive protein levels and infection of carotid artery atherosclerotic plaque with viable C pneumoniae.	11739967
Necrotizing granulomatous inflammation, Parathyroid Adenoma, Hyperparathyroidism, Primary	Altered Intercellular Communication	Tuberculous granulomatous inflammation associated with adenoma of parathyroid gland manifesting as primary hyperparathyroidism.	11740057
Inflammation, Parathyroid Adenoma, Neoplasms	Altered Intercellular Communication	A positive PCR for Mycobacterium tuberculosis of the homogenates of parathyroid tumor confirmed tuberculous inflammation within the parathyroid adenoma.	11740057
Ovarian failure	Altered Intercellular Communication	Successful pregnancy in a woman with ovarian failure associated with mutation in the beta-subunit of luteinizing hormone.	11740150
Infertility, Disorder of endocrine ovary	Altered Intercellular Communication	We report a successful pregnancy in a woman with severe ovarian dysfunction and infertility associated with a variant beta-subunit of luteinizing hormone (LH).	11740150
Intraocular inflammation	Altered Intercellular Communication	High TGFbeta2 concentrations in the eyes without intraocular inflammation suggest its immunosuppressive role in human eyes.	11740849
Hypertrophy, prostatitis	Altered Intercellular Communication	Prostatic inflammation associated with benign hypertrophy can cause false positives in both tPSA and f/tPSA measurements, since 60% of these patients have an f/tPSA ratio below 16%.	11741128
Inflammation, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	Vasectomy, inflammation, atherosclerosis and long-term followup for cardiovascular diseases: no associations in the atherosclerosis risk in communities study.	11743306
Inflammation, Atherosclerosis, Cerebrovascular accident, Coronary heart disease, Peripheral Vascular Diseases, Dental Plaque	Altered Intercellular Communication	We assessed the association of vasectomy with inflammation and coagulation factors, carotid intimal-medial thickness, carotid plaque, prevalent peripheral arterial disease, and incident coronary heart disease and stroke in the Atherosclerosis Risk in Communities cohort.	11743306
Inflammation, Coronary heart disease, Cerebrovascular accident, Peripheral Vascular Diseases, Dental Plaque	Altered Intercellular Communication	Multivariate analysis showed no association of vasectomy status with inflammation or coagulation factors, peripheral arterial disease, carotid plaque, carotid far wall thickness, incident coronary heart disease or stroke.	11743306
Inflammation	Altered Intercellular Communication	Proteoglycans such as CD44 may contribute to the presentation of these soluble angiogenic factors at the inflammation site.	11743354
Chronic liver disease, Fibrosis Assessment, Inflammation, Hepatitis C, Chronic	Altered Intercellular Communication	Integrin up-regulation in chronic liver disease: relationship with inflammation and fibrosis in chronic hepatitis C. In 94 patients with chronic hepatitis C, the pattern of integrin expression was correlated with firstly, the histological activity index, necro-inflammatory grade, and stage of fibrosis; secondly, the expression of inflammatory markers including ICAM-1; and thirdly, the extent and intensity of laminin deposition in the perisinusoidal matrix.	11745680
Inflammation	Altered Intercellular Communication	Arterial wall MRI characteristics are associated with elevated serum markers of inflammation in humans.	11747026
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation contributes to atherosclerosis, but assessment in humans is largely restricted to measurement of markers in blood.	11747026
Inflammation	Altered Intercellular Communication	We determined whether MRI properties of large arteries were associated with markers of inflammation in serum.	11747026
Inflammation, Atheroma	Altered Intercellular Communication	Thus, MRI characteristics of the aorta and carotid arteries were associated with elevated serum markers of inflammation, frequently in the absence of definite atheroma.	11747026
Inflammation	Altered Intercellular Communication	MRI of large arteries may provide a new approach to investigate the contribution of inflammation to atherogenesis.	11747026
Inflammation	Altered Intercellular Communication	Chemokines: reliable markers for diagnosis of rejection and inflammation following orthotopic liver transplantation.	11750409
Bronchitis, Chronic, Inflammation	Altered Intercellular Communication	Interleukin-4 and interleukin-5 gene expression and inflammation in the mucus-secreting glands and subepithelial tissue of smokers with chronic bronchitis.	11751191
ARCN1 gene, Inflammation, Airway structure, cinobufotalin, Airway Obstruction, Bronchitis	Altered Intercellular Communication	We conclude that there is increased inflammation and IL-4 gene expression in the mucus-secreting glands and the airway mucosa of smokers with bronchitis: both are lower in those with CB and coexisting COPD suggesting that airway inflammation in CB is reduced when airway obstruction develops.	11751191
Glandular part of prostate, Leucocytic infiltrate, prostatitis	Altered Intercellular Communication	The peripheral hypoechoic rim accompanying prostatic inflammation and revealed by TRUS reflects a sparsity of prostate glandular tissue and is thought to be an area in which inflammatory cell infiltration is minimal.	11752987
Inflammation, Malabsorption Syndrome	Altered Intercellular Communication	Laboratory results showed signs of inflammation and malabsorption.	11753737
Data types - Address	Altered Intercellular Communication	Based on our findings, it is unlikely that neuronal COX-2 contributes to pathology in end stage AD; however, COX-2 in other cell types may participate in the inflammation-related response associated with the disease.	11754989
Data types - Address	Altered Intercellular Communication	These findings indicate that astrocytes are the predominant source of CD40L in brain, and are consistent with the proposed role of CD40L-mediated neurotoxic inflammation in AD.	11755016
Inflammation, Creutzfeldt-Jakob disease	Altered Intercellular Communication	In order to investigate inflammation and apoptosis in Creutzfeldt-Jakob disease (CJD) patients, we analyzed astrocytes, microglia and apoptotic neurons in brain and IL-1beta in cerebrospinal fluid (CSF).	11755020
Postoperative endophthalmitis, Uveitis	Altered Intercellular Communication	Actinomyces species can rarely cause postoperative endophthalmitis, and it should be considered in cases of severe postoperative intraocular inflammation.	11755855
Inflammation	Altered Intercellular Communication	Histopathological examination of the extruded implant, LE, showed marked inflammation and evidence of foreign body reaction.	11755856
Inflammation, Syndrome	Altered Intercellular Communication	Excess inflammation in eyes with immune recovery vitritis syndrome may trigger a foreign body reaction that results in a delayed extrusion of primary ganciclovir implants.	11755856
Inflammation, Atherosclerosis	Altered Intercellular Communication	Nuclear factor-kappaB (NF-kappaB) is a transcription factor which plays a coordinating role in inflammation and cellular proliferation and is thought to be involved in the pathogenesis of atherosclerosis.	11755932
Pain Distress Question, Neurogenic Inflammation, Complex Regional Pain Syndromes	Altered Intercellular Communication	To test the contribution of neurogenic inflammation and neuropeptide release to the pathophysiology of complex regional pain syndrome (CRPS).	11756594
Neurogenic Inflammation, Complex Regional Pain Syndromes	Altered Intercellular Communication	This investigation was prompted by a recent study by the authors that suggested a facilitated neurogenic inflammation in CRPS.	11756594
Neurogenic Inflammation, Complex Regional Pain Syndromes, Edema	Altered Intercellular Communication	Increased systemic CGRP levels in patients with acute CRPS suggest neurogenic inflammation as a pathophysiologic mechanism contributing to vasodilation, edema, and increased sweating.	11756594
Pain Distress Question, Irritation	Altered Intercellular Communication	Oral lichen planus (OLP) is a relatively common, chronic inflammatory condition, which frequently presents with symptoms of pain and irritation.	11756942
Inflammation, Temporomandibular Joint, Paresthesia	Altered Intercellular Communication	Complications included localized inflammation at the distraction device site (n = 2), temporary temporomandibular joint (TMJ) discomfort during distraction process (n = 1), and temporary paresthesia of the inferior alveolar nerve distribution (n = 2).	11756997
Orchitis	Altered Intercellular Communication	Echo color Doppler examination is more sensitive than ultrasonography alone for revealing testicular inflammation.	11758024
Communicable Diseases, Inflammation	Altered Intercellular Communication	Chronic inflammation, which was thought to be caused by infection, was detected at the stenotic conduit by biopsy.	11758363
Azoospermia, Oligospermia, Ejaculatory duct structure	Altered Intercellular Communication	In an infertile male with oligospermia or azoospermia with low ejaculate volume, normal secondary sex characteristics, testes and normal hormonal profiles, ejaculatory duct obstruction is suggested.	11758851
Inflammation, Hydrocephalus	Altered Intercellular Communication	MRI revealed hydrocephalus internus with signs of inflammation of mastoid cells and cavum tympani indicating explorative myringotomy and antrotomy.	11759212
Periodontitis, Dental Plaque	Altered Intercellular Communication	Periodontitis is an inflammatory condition of tooth-supporting tissues that is usually treated by mechanical removal of plaque and microorganisms that adhere to teeth.	11759865
Gingivitis, Periodontal Attachment Loss, Gingival Overgrowth	Altered Intercellular Communication	Most erupted teeth showed severe gingival inflammation with some gingival overgrowth and various degrees of periodontal attachment loss.	11759873
Progressive neurologic deterioration, Cryptococcus	Altered Intercellular Communication	However, neurological deterioration and reconfirmation of C. neoformans in CSF indicated recurrent cryptococcal inflammation.	11760390
Inflammation, Meningoencephalitis	Altered Intercellular Communication	Such cerebral sulcal hyperintensity is an unusual MR imaging finding of cryptococcal meningoencephalitis, and may be an early sign of procrastinating process or recurrent inflammation even if the findings of CSF obtained by lumbar puncture are normal.	11760390
glottis	Altered Intercellular Communication	Direct laryngoscopy performed in the operating room showed mild glottic and subglottic inflammation.	11760673
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Microscopic examination was performed the similar percentage the stage of inflammation and fibrosis.	11761813
Inflammation, Cutaneous Small Vessel Vasculitis	Altered Intercellular Communication	PTX3 in small-vessel vasculitides: an independent indicator of disease activity produced at sites of inflammation.	11762945
Inflammation	Altered Intercellular Communication	Nitric oxide (NO) formation is increased during inflammation.	11764219
Granulomatous inflammation	Altered Intercellular Communication	The histologic examination of the tracheal mucosa showed granulomatous inflammation.	11765451
Retinal Vasculitis, Vasculitis, CTCAE	Altered Intercellular Communication	Isolated retinal vasculitis (IRV) is a form of retinal vasculitis without other inflammations of the eye or systemic vasculitis.	11765471
Inflammation, Liver Dysfunction	Altered Intercellular Communication	Severe inflammation and liver dysfunction were indicated by blood test.	11766383
Inflammation	Altered Intercellular Communication	We noted thickened vessel walls and an augmentation of the synovial surface, whereas typical inflammation could not be demonstrated in any of the histological specimens.	11766655
Vascular lesions	Altered Intercellular Communication	Our histological and immunohistochemical findings, as well as data from the literature, support the view that at least some vascular lesions may result from hormonal stimulation.	11766743
Inflammation, Necrosis	Altered Intercellular Communication	Spinal cord biopsy of the lesion revealed inflammation with necrosis and also grew listeria.	11766781
Physiologic Intraocular Pressure, Exophthalmos, Orbital Cellulitis, Uveitis	Altered Intercellular Communication	The ocular lesions caused by the sinusal inflammations were: acute uveitis, orbital cellulitis, unilateral exophthalmia without obvious inflammatory signs.	11771105
Inflammation, Myositis	Altered Intercellular Communication	Deltoid muscle biopsy performed one year earlier at another hospital showed mild myopathic changes without inflammation, but there were scattered thick-walled endomysial capillaries, suggesting inflammatory myopathy.	11771157
Inflammation, Biceps brachii muscle structure	Altered Intercellular Communication	Biceps brachii muscle biopsy in our hospital showed marked inflammation with perifascicular atrophy.	11771157
Rhabdomyositis, Scleroderma , Myocardium	Altered Intercellular Communication	In this patient, the cardiac muscle involvement progressed together with the skeletal muscle inflammation before scleroderma became apparent.	11771157
Inflammation, Arthritis	Altered Intercellular Communication	Of particular importance is that IMS decreased if a patient developed active arthritis in the knee, and normalised again when the inflammation decreased.	11771527
Eye, Complication Aspects, Inflammatory abnormality of the eye	Altered Intercellular Communication	The parameters evaluated were ocular stage at presentation, visual acuity, ocular complications, disease progression, control of ocular inflammation, and presence of extraocular involvement.	11772589
Inflammation, Hypoalphalipoproteinemias, Dyslipidemias	Altered Intercellular Communication	Our study investigated whether familial hypoalphalipoproteinemia, a genetic form of dyslipidemia characterized by very low HDL levels, might be associated with increased inflammation markers such as C-reactive protein.	11772869
Inflammation, Hypoalphalipoproteinemias, Coronary Arteriosclerosis	Altered Intercellular Communication	Elevation of C-reactive protein values in familial hypoalphalipoproteinemia, in the absence of signs and symptoms of local or systemic inflammation or systemic or recurrent disease, may suggest an upregulation of proinflammatory mechanisms, which is further exacerbated by the presence of coronary atherosclerotic disease.	11772869
Lymphoid hyperplasia, Chronic Lymphocytic Leukemia, Orbital Pseudotumor, Malignant lymphoma - lymphoplasmacytic	Altered Intercellular Communication	Chromosomal imbalances were detected in 0 of 6 patients with idiopathic orbital inflammation, 0 of 2 with benign reactive lymphoid hyperplasia, 3 of 3 with highly malignant diffuse large B-cell lymphoma, 4 of 10 with marginal zone B-cell lymphoma, 0 of 1 with chronic lymphatic leukemia lymphoma, and 1 of 4 with immunocytoma.	11773006
Squamous cell carcinoma, Hypercalcemia, CTCAE	Altered Intercellular Communication	Hypercalcemia associated with parathyroid hormone-related protein at the terminal stage of uncomplicated squamous cell carcinoma in the head and neck region.	11774403
Inflammation, Colitis	Altered Intercellular Communication	Previous research has demonstrated that ligands for the gamma subtype of peroxisome proliferator-activated receptors (PPARs) reduce inflammation in two different murine models of colitis.	11774944
Inflammation	Altered Intercellular Communication	In contrast, the histological activity indices of inflammation and fibrosis/cirrhosis were poorly correlated between lobes (p = 0.038, r = 0.60, and p = 0.098, r = 0.50, respectively).	11774953
Airway structure	Altered Intercellular Communication	[Kinin generation in acute and chronic airway inflammation].	11775811
Airway structure	Altered Intercellular Communication	To investigate the kinin generation pathways in acute and chronic airway inflammation.	11775811
Airway structure	Altered Intercellular Communication	BALF from patients with acute, chronic airway inflammation and healthy controls were collected.	11775811
Airway structure, Inflammation	Altered Intercellular Communication	The results indicated that in acute airway inflammation kinins seem to be mainly generated by PK, whereas in chronic inflammation kininogenases other than PK--such as TK--seem to be more important.	11775811
ARCN1 gene, Airway structure	Altered Intercellular Communication	822 cases(account for 24.6% of investigated subjects) of COPD due to smoking were identified, and 624 cases were found (account for 40.4% of investegated subjects) to have a history of both smoking and chronic airway inflammation.	11775857
Airway structure, Inflammation, Asthma	Altered Intercellular Communication	IL-16 is involved in the asthmatic process by recruiting CD4+ T cells and thus plays an important role in CD4+ cell-dependent eosinophilic inflammation in asthmatic airways.	11775918
Inflammation, Disease	Altered Intercellular Communication	IL-1beta, IL-1Ra and sIL-1RII in the culture supernatants of PMN and PBMC and the serum levels in patients with inflammation and patients with cancer disease of the same location.	11776404
Inflammation	Altered Intercellular Communication	An inflammation or an other malignant process may create a microenvironment that modulates the production and activity of cytokines and their regulators.	11776404
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The results obtained revealed changes in the secretion of IL-1beta and IL-1Ra which are more characteristic of PMN and PBMC from cancer patients than of the cells from patients with inflammation.	11776404
Inflammation	Altered Intercellular Communication	Angiotensin-converting enzyme (ACE) plays a key role in the metabolism of angiotensin II (AT II) and inactivation of bradykinins and tachykinins, which are potent bronchial constrictors and mediators of inflammation asthma, and ACE is heavily expressed in the lungs.	11776522
Inflammation	Altered Intercellular Communication	A genetic factor is believed to predispose to the development of chronic inflammation in response to an unidentified stimulus.	11776720
Gastritis, Atrophic	Altered Intercellular Communication	Assessment of apoptosis in vitro identified a group of H. pylori isolates that induce more severe gastric inflammation and atrophy.	11777849
Inflammation, Swelling	Altered Intercellular Communication	Physical examination revealed swelling and inflammation of both ankles.	11778155
Osteomyelitis, Granuloma	Altered Intercellular Communication	The main pathological appearances were granulomatous lesions and nonspecific chronic pyogenic inflammations.	11778218
Airway structure, ARCN1 gene	Altered Intercellular Communication	IL-8, TNF-alpha and neutrophil are involved in airway inflammation which results in airflow obstruction, thus playing an important role in the pathogenetic process of COPD.	11778258
Airway structure, ARCN1 gene, Neurogenic Inflammation	Altered Intercellular Communication	These data suggest that neurogenic inflammation may be involved in the airway inflammation process and subsequent airway narrowing in COPD.	11778483
Inflammation, Retinitis Pigmentosa, Cartilaginous joint structure, MULTISYSTEM DISORDER	Altered Intercellular Communication	RP is a rare multisystem disorder characterized by recurrent inflammation and progressive degeneration of cartilaginous structure and connective tissue.	11778488
Communicable Diseases, Inflammation	Altered Intercellular Communication	We suggest that simple CO measurements in exhaled air can detect the inflammatory process within the airways caused by infection and that a repeat measurement can be used to assess the nature of inflammation.	11778786
Airway structure, ARCN1 gene	Altered Intercellular Communication	In conclusion, sputum induction is safe and the cell and fluid phase mediators repeatable in the investigation of airway inflammation in patients with COPD.	11778799
Communicable Diseases, Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Chronic subclinical infection or inflammation may account for this association, and modification of these inflammatory pathways may provide a novel approach to stroke prevention.	11779885
Atherosclerosis	Altered Intercellular Communication	Recent evidence suggests that atherosclerosis is an inflammatory condition.	11779885
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The study was undertaken to determine whether mucosal and plasma concentrations of PGE2 can be considered as a surrogate marker of bowel inflammation activity in patients with ulcerative colitis.	11780581
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	These data confirm possible usefulness of plasma or mucosal PGE2 measurement in patients with ulcerative colitis as a possible marker of inflammation.	11780581
Inflammation	Altered Intercellular Communication	We investigated the mucosal flora of washed colonoscopic biopsies of 305 patients with bowel inflammation and 40 controls.	11781279
Inflammation	Altered Intercellular Communication	We found high concentrations of mucosal bacteria in patients with bowel inflammation, but not in controls.	11781279
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Our findings suggest that the changes in the mucosal flora in IBD are not secondary to inflammation, but a result of a specific host response.	11781279
Inflammation, Neoplasms, Muscle (organ)	Altered Intercellular Communication	Inflammation occurred in 65% of the tumors, and a smooth muscle reaction, identified by an increased Ki-67 index, was present in most cases.	11781521
Inflammation, Duodenal Ulcer	Altered Intercellular Communication	Since family studies have shown the importance of the genetic background of the host in the development of gastric and duodenal ulcers, immunogenetic factors involved in the regulation of inflammation deserve further study.	11781708
Inflammation, Neoplasms, Disease susceptibility	Altered Intercellular Communication	The TP slides were analyzed for overall cellularity (percent circle coverage by epithelial cells), tumor cellularity, tumor diathesis, inflammation, coexistent dysplasia, and keratinization.	11782077
Inflammation, Disease susceptibility	Altered Intercellular Communication	It could be hypothesized that tumor diathesis and inflammation may be the etiology for decreased cellularity by blocking filter coverage by epithelial cells.	11782077
Cancer-related fatigue, Inflammation	Altered Intercellular Communication	Determination of urinary IL-6 level is useful in studying the severity of immune inflammation of CRF.	11783309
Inflammation, Retinitis Pigmentosa	Altered Intercellular Communication	RP improves renal function by inhibiting the production of IL-6 and lowering immune inflammation.	11783309
palladium, Inflammation	Altered Intercellular Communication	The AGE-RAGE interaction resulted in HPMC activation, which may promote local inflammation, and thus is implicated in the peritoneal injury found in long-term PD patients.	11786095
Suppuration, Inflammation, Bronchiolitis	Altered Intercellular Communication	Thoracoscopic lung biopsy revealed diffuse bronchiolitis with suppurative intrabronchiolar inflammation, lymphohistiocytic "cuffing" of the bronchioli, and foam cell aggregates within neighboring alveoli.	11787856
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Elevated serum iron markers were associated with male sex, increased alcohol consumption, and increased liver inflammation and fibrosis.	11788568
Hepatitis C, Hepatitis	Altered Intercellular Communication	Patients with elevated LICs were older, acquired HCV infection earlier, and had more liver inflammation.	11788568
Orbital Pseudotumor	Altered Intercellular Communication	The chronic course of idiopathic intestinal inflammations is characterized also by a relatively high incidence of complications, local ones affecting the entire large intestine, as well as extraintestinal ones in remote organs.	11789007
Inflammation, Reperfusion Injury	Altered Intercellular Communication	Cytokines have been shown to play an important role in promoting inflammation in the setting of ischemia-reperfusion injury.	11790657
Inflammation, Genus Dermatobia	Altered Intercellular Communication	The periorbital inflammation was a result of a larva of the human botfly, Dermatobia hominis.	11791112
Communicable Diseases, Inflammation	Altered Intercellular Communication	The results were as follows: 55.1% of the visit/sites demonstrated an absence of inflammation; 32.3% of the visit/sites demonstrated slight redness; 4.7% demonstrated red and moist peri-implant tissues; 5.5% demonstrated granulation tissue associated with the implants; and in 2.4% of the implants, infection of the peri-implant soft tissues was noted.	11791267
Neoplasms, Chronic sclerosing sialadenitis, Malignant Childhood Neoplasm	Altered Intercellular Communication	Kuttner tumor or chronic sclerosing sialadenitis is a benign inflammatory condition of the submandibular gland that mimics a malignant neoplasm clinically because of presentation as a hard mass.	11791589
Refractory anemias, Inflammation	Altered Intercellular Communication	Serum YKL-40 levels partially reflect the degree of inflammation and also reflect the joint destruction in patients with RA.	11791636
Inflammation, Spanish Language, Spondylarthritis	Altered Intercellular Communication	An intriguing link between gut and synovial inflammation exists in patients with spondyloarthropathy (SpA), illustrated by the high frequency of microscopically inflammatory gut lesions observed in these patients.	11791640
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	We investigated whether inflammation might promote the development of paroxysmal atrial fibrillation (PAF), and whether high levels of CRP are associated with an increased risk of PAF.	11791805
Bacterial sinusitis, Neoplasms, Granulomatous inflammation, Mycoses, Sphenoidal sinus	Altered Intercellular Communication	The differential diagnosis of isolated sphenoid sinus disease includes bacterial sinusitis, fungal infection, granulomatous inflammation, mucocele, and tumors.	11792055
Inflammation	Altered Intercellular Communication	High-sensitivity C-reactive protein (CRP), proposed as a new coronary risk marker, may reflect either an acute phase reaction or the level of chronic inflammation.	11792332
Heart Diseases, Inflammation, Malnutrition	Altered Intercellular Communication	Inflammation, malnutrition, and cardiac disease as predictors of mortality in hemodialysis patients.	11792759
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Several morbidity factors that per se increase the risk of a poor outcome, such as cardiovascular disease (CVD) and inflammation, may also cause malnutrition.	11792759
Inflammation, Malnutrition, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	Inflammation, malnutrition, and CVD appeared to contribute to increased mortality in a stepwise manner.	11792759
Inflammation, Malnutrition, HD Term Type, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus	Altered Intercellular Communication	It is concluded that in addition to malnutrition and comorbidities (CVD, diabetes mellitus), inflammation (elevated s-CRP) is a significant independent risk factor for mortality in HD patients.	11792759
Inflammation, Malnutrition	Altered Intercellular Communication	Inflammation, malnutrition, and CVD appear to be interrelated, each additionally contributing to the high mortality in these patients.	11792759
Inflammation, immunoglobulin A	Altered Intercellular Communication	Patients with raised IgA AGA seem to have more pronounced inflammation than those with a low IgA AGA concentration.	11792877
Actinomycosis, Granulomatous inflammation, Abscess, Chronic disease	Altered Intercellular Communication	Actinomycosis is subacute or chronic disease manifested by a defined granulomatous inflammation with the development of infiltrates, abscesses and fistulae.	11794061
Inflammation, Actinomycosis	Altered Intercellular Communication	Histological examination revealed a suppurative, partly fibroproductive inflammation with an actinomycotic etiopathology.	11794061
Hypersensitivity, Interstitial inflammation	Altered Intercellular Communication	Myocardial biopsies showed massive interstitial inflammation with a predominance of eosinophilic cells suggesting a hypersensitivity reaction.	11794987
Communicable Diseases, Inflammation, atherosclerotic, Atherosclerosis	Altered Intercellular Communication	Out of 14 anti-Cag A positive patients 11 showed positive detection of H. pylori DNA (p = 0.015) 1) There is a significant link between CAD and infection with H. pylori, especially expressing CagA proteins; 2) Patients infected with CagA-positive H. pylori show significantly greater coronary artery lumen loss and arterial re-stenosis after PTCA with stent implantation; 3) H. pylori eradication significantly attenuates the reduction in coronary artery lumen in CAD patients after PTCA possibly due to the elimination of chronic inflammation and the decline in proinflammatory cytokine release and 4) The identification of DNA in atherosclerotic plaques of patients with severe CAD supports the hypothesis that infection with H. pylori (especially CagA positive) may influence the development of atherosclerosis.	11795863
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inappropriate inflammation is a key mechanism in the development of atherosclerosis.	11796395
Inflammation	Altered Intercellular Communication	These data strongly suggest that serum MMP-3 reflects synovial inflammation.	11796404
Inflammation	Altered Intercellular Communication	The inflammation was mostly mononuclear and formed microglial nodules and perivascular clusters in the white and gray matter.	11797775
Inflammation	Altered Intercellular Communication	The erbium:YAG laser (Er:YAG) with a wavelength of 2.94 microm allows precise ablation avoiding strong inflammation.	11798495
Inflammation, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Fibrosis indexes were compared according to inflammation grade, fibrosis stage and chronic hepatitis degree.	11798612
Inflammation, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	In the 2600 serum samples from chronic hepatitis patients, fibrosis indexes (including HA, PC III, LN and IV-C) had significant correlation with inflammation grade, fibrosis stage and the degree of chronic hepatitis (P < 0.01).	11798612
Inflammation, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Serum fibrosis indexes are fairly well correlated with the inflammation grade, fibrosis stage and the degree of chronic hepatitis.	11798612
Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	[Helicobacter pylori associated gastric mucosal inflammation and histopathological assessment].	11798973
Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	To investigate the pathological features of Helicobacter pylori associated gastric mucosal inflammation and to establish relevant histopathological assessment standards.	11798973
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Biopsy specimens from the gastric antrum, body of stomach, and gastric angle were taken from 2 134 cases of H. pylori associated gastric mucosal inflammation.	11798973
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Scoring of severity of mucosal inflammation reflected the status of H. pylori infection and was not influenced by the biopsy site, size of specimen, and direction of sectioning.	11798973
Inflammation	Altered Intercellular Communication	Severe active inflammation could be seen in 39.6% of the H. pylori positive cases, and 0.4% of the H. pylori negative cases.	11798973
Inflammation, Colonization	Altered Intercellular Communication	The severity score of inflammation was significantly correlated with the amount of H. pylori colonization.	11798973
Allergic, Nasal Polyps, Inflammation	Altered Intercellular Communication	Therefore, 1) the presence of GRs and COX-2 in nasal polyps from nonallergic patients, as well as upregulation of COX-2 expression, suggests that inflammation may play an important role in the pathophysiology of nasal polyps; and 2) glucocorticoid could be a potential treatment method for suppressing inflammatory processes.	11800371
Inflammation, Dermatologic disorders	Altered Intercellular Communication	We compared epidermal thickness, rete ridge length, mitotic activity, atypia, dermal collagen change, dermal inflammation, and presence of other dermatoses in 30 women in each group.	11801773
Inflammation, Carcinoma, Fibrosis Assessment, Vulvar Lichen Sclerosus, Simple lobule of cerebellum, Vulval intraepithelial neoplasia	Altered Intercellular Communication	Vulvar lichen sclerosus adjacent to carcinoma showed increased epidermal thickness (0.61 mm versus 0.26 mm; P < 0.005), more dermal fibrosis (P < 0.0005), more inflammation (P < 0.0005), and more simplex (differentiated) vulvar intraepithelial neoplasia (18 cases versus 1 case; P < 0.0005) compared with that distant from carcinoma.	11801773
Inflammation, Lofgrens syndrome, Fever, CTCAE, hilar adenopathy, Arthritis, Erythema Nodosum	Altered Intercellular Communication	A 39-year-old man presented with fever, arthritis of knees and wrists, periarticular ankle inflammation, erythema nodosum, bilateral hilar adenopathy and diffuse pulmonary parenchymal changes, due to Lofgren's syndrome.	11802332
Necrotizing granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	Pathologic examination of the biopsy specimen revealed chronic granulomatous inflammation and positive acid-fast staining, which confirmed the diagnosis of chest wall tuberculosis infection.	11802524
Airway structure, Asthma, Sudden death	Altered Intercellular Communication	Severe nonspecific airway inflammation is demonstrated in asthmatic patients with sudden death.	11802980
Airway structure, ARCN1 gene, Bronchitis, Chronic	Altered Intercellular Communication	(1) The characteristics of non-specific airway inflammation in patients with chronic bronchitis and COPD is the increased numbers of neutrophils and AMs.	11802988
Pericholecystic abscess, Biliary calculi	Altered Intercellular Communication	The following findings were evaluated: distention, mural thickening, wall enhancement, irregular wall, wall striation, intraluminal membranes, pericholecystic inflammation, gallstones, pericholecystic fluid, enhancement of liver parenchyma, pericholecystic abscess, and gas in the wall or lumen.	11804880
Inflammation	Altered Intercellular Communication	Stool, granulation tissue, and inflammation can mimic the CT appearance of local recurrence or metachronous disease and account for false-positive examinations.	11804881
Inflammation, Calcinosis	Altered Intercellular Communication	Inflammation, calcification, and medial thinning are primary determinants of positive remodeling, which appears to be a feature of plaque instability.	11804983
Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	These data support the hypothesis that accumulation of this endogenous inhibitor of NO synthase is an important risk factor for cardiovascular disease in chronic renal failure and suggest a possible link between ADMA and inflammation.	11805179
Orchitis	Altered Intercellular Communication	To study biochemical indicators of the hematosalivary barrier operation in varying activity of articular inflammation and their correlations.	11806220
Cervical Squamous Cell Carcinoma, Inflammation	Altered Intercellular Communication	C. trachomatis infection was found to be a possible cofactor of HPV in the etiology of squamous cervical cancer, and its effect may be mediated by chronic inflammation.	11807714
Inflammation, muscle mass	Altered Intercellular Communication	Since the serum cystatin-C concentration is not affected by muscle mass nor inflammation, it has been postulated to be an improved marker of glomerular filtration rate (GFR) compared with the serum creatinine level.	11808075
Fibrosis, Liver, Hepatitis, Chronic, Hepatitis	Altered Intercellular Communication	These results suggest that phlebotomy with maintenance lowers serum aminotransferase levels, improves liver inflammation, and suppresses the progression of liver fibrosis in chronic hepatitis C.	11808937
Inflammation	Altered Intercellular Communication	A significant correlation was found between urinary iPF2alpha-III and plasma C-reactive protein concentrations, suggesting a link between lipid peroxidation and inflammation.	11808977
Airway structure, Celiac Disease	Altered Intercellular Communication	We report one such case where there was bronchoscopic evidence of lymphocytic airway inflammation in association with newly diagnosed coeliac disease.	11809998
Inflammation, Gammopathy, Peripheral demyelinating neuropathy	Altered Intercellular Communication	As T cells in sural nerve biopsy specimens may represent a marker of inflammation, we analyzed whether the presence of sural nerve T cells in patients with demyelinating polyneuropathy associated with monoclonal gammopathy may help to define a specific clinical entity.	11810175
Necrotizing granulomatous inflammation, Neoplasms	Altered Intercellular Communication	Histopathologic examination showed chronic granulomatous inflammation with no evidence of neoplasm.	11811862
Inflammation, Interstitial Fibrosis Assessment	Altered Intercellular Communication	The major morphologic changes were as follows: histologically, alveolar inflammation and interstitial fibrosis were observed.	11812351
Chronic lymphocytic inflammation, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Mucous purulent plugs, interrupted elastic fibers in bronchial wall and chronic inflammation accompanied with lymphocytes infiltration in fibrosis area could also be seen.	11812352
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The genesis of pulmonary fibrosis might be associated with chronic inflammation accompanied with lymphocytes.	11812352
Inflammation, Sore to touch	Altered Intercellular Communication	The main complications that were recorded were sore wounds in 15%, inflammation in the entrance of the screws in 9%, and aseptic loosening of the femoral screws/loss of reduction in varus >10 degree in 8%.	11812485
Inflammation, Discitis, Bacterial Infections	Altered Intercellular Communication	Discitis (inflammation of the intervertebral disk) most commonly develops as a rare complication of bacterial infection or chemical or mechanical irritation during spine surgery (1) with a postoperative incidence of 1%-2.8% (2).	11812710
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Chronic low-grade inflammation may be involved in the pathogenesis of insulin resistance and type 2 diabetes.	11812755
Gastritis, Cardia of stomach	Altered Intercellular Communication	Gastric inflammation and H. pylori density within biopsy samples from the antrum (n = 4), corpus (n = 4), cardia (n = 2), fundus (n = 2), duodenum (n = 2) and distal esophagus (n = 1) were assessed.	11813622
Tissue damage, Inflammation	Altered Intercellular Communication	The urokinase plasminogen-activator receptor (uPAR) is involved in many processes in inflammation including the migration of inflammatory-associated cells to sites of tissue damage.	11814408
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Fucosylation of alpha1-acid glycoprotein (orosomucoid) compared with traditional biochemical markers of inflammation in recent onset rheumatoid arthritis.	11814479
Inflammation	Altered Intercellular Communication	We compared the results with traditional biochemical markers of inflammation, i.e.	11814479
Enteritis, Allergy - Charge Type Reason	Altered Intercellular Communication	Large intestine inflammation was observed in food allergy process in 7 children.	11816299
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	In the cases of food allergy in children the inflammation changes in mucosa can be seen in all of its sections.	11816299
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	Over 2/3 of examined children with food allergy showed inflammation and inflammation-atrophical changes in alimentary tract mucosa.	11816299
Xanthogranulomatous inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histopathological examination of resected specimens showed dense fibrosis and xanthogranulomatous inflammation with foamy cells and giant cells.	11816467
Inflammation	Altered Intercellular Communication	Anti-beta2 glycoprotein I antibodies cause inflammation and recruit dendritic cells in platelet clearance.	11816715
Inflammation	Altered Intercellular Communication	We conclude that anti-beta2GPI antibodies cause inflammation during platelet clearance and shuttle platelet antigens to antigen presenting DCs.	11816715
Presenile dementia, THANATOPHORIC DYSPLASIA, TYPE I (disorder)	Altered Intercellular Communication	In contrast, new cholinesterase inhibitors, developed for the treatment of dementia, may improve TD by directly increasing cholinergic synaptic transmission.	11816865
Inflammation, Abscess of pituitary	Altered Intercellular Communication	With light microscopy, chronic non-specific inflammation and a pituitary abscess capsule were demonstrated in the tissue.	11817714
hearing impairment, Inflammation	Altered Intercellular Communication	Hearing loss is treated with drugs that provide better blood supply to the inner ear and decrease inflammation.	11817844
Inflammation	Altered Intercellular Communication	The usefulness of an inflammation meter to detect the presence of infection/inflammation in elderly patients.	11818432
Inflammation	Altered Intercellular Communication	Beta-amyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: role of inflammation.	11818564
Gastritis, Epithelial, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The following parameters were considered: presence and type of gastritis, grade of mucosal inflammation, presence and percentage of complete or incomplete metaplasia, presence and grade of inflammatory activity, presence and number of lymphoid follicles (primary and secondary), presence and number of eosinophils in the mucosa, presence of H. pylori and presence of epithelial edema.	11818986
Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Statistical differences were found in relation to : grade of mucosal inflammation (p: 0.042), presence of superficial eosinophils on the surface (p: 0.019) and presence of Helicobacter pylori (p: 0.024).	11818986
Inflammation, Gastritis, Eosinophilic inflammation	Altered Intercellular Communication	Nodular gastritis is a chronic gastritis with superficial eosinophilic infiltration, moderate inflammation and an important inflammatory activity associated with the presence of H. pylori.	11818986
Intraocular inflammation, Macular Edema, Cystoid	Altered Intercellular Communication	Intraocular pressure (IOP), intraocular inflammation, cystoid macular edema (CME), and best corrected visual acuity (BCVA) were evaluated 1, 3, and 6 months postoperatively.	11821215
Inflammation	Altered Intercellular Communication	An uncontrollable IOP rise and inflammation prompted an early vitrectomy in 11 eyes in Group 1.	11821215
Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation was no longer detectable 1 month after vitrectomy but persisted during the entire follow-up in Group 2.	11821215
Retinal Detachment, Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation, increased IOP, and CME were major complications in nonvitrectomized eyes after phacoemulsification; retinal detachment occurred in 2 vitrectomized eyes.	11821215
Inflammation	Altered Intercellular Communication	Conservative management is feasible at the price of long-term intraocular inflammation and slower restoration of comparable visual function.	11821215
Inflammation, Dropouts	Altered Intercellular Communication	Centrilobular necrosis was associated with centrilobular swelling, dropout, endotheliitis, and inflammation.	11821740
Necrotizing granulomatous inflammation, Biliary calculi	Altered Intercellular Communication	A partial cystectomy was performed; macroscopic and histologic examination documented a central nidus of fragmented gallstones and a picture of chronic granulomatous inflammation.	11822861
Hemangioma, Cavernous, Lymphoma, Orbital Pseudotumor	Altered Intercellular Communication	The most common diagnoses were malignant lymphoma in 47 patients (24%), idiopathic orbital inflammation in 19 (10%), and cavernous hemangioma in 15 (8%).	11825802
Inflammation, Panuveitis, Choroiditis	Altered Intercellular Communication	Immunomodulatory therapy controls inflammation and preserves vision in patients with multifocal choroiditis and panuveitis.	11825826
Granulomatous inflammation	Altered Intercellular Communication	Cytologic examination of the specimen obtained with fine needle aspiration of the pleural and parasternal masses yielded granulomatous inflammation.	11828216
Tumor necrosis, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	Tumor necrosis factor-alpha (TNF-alpha) is one of the cytokines secreted by macrophages and is related to a sequence of events in response to inflammation and cancer formation.	11828995
Gingivitis, penicillin G, Gastrointestinal mucositis	Altered Intercellular Communication	Plasma cell gingivitis (PCG), an infrequent benign inflammatory condition of unknown etiology, is a type of plasma cell orificial mucositis, which includes a wide spectrum of conditions.	11829177
Ear Inflammation	Altered Intercellular Communication	However, 27E10 positivity was detected in three of ten TBs with signs of chronic ear inflammation.	11829190
Inflammation, Primary malignant neoplasm, Blood Clot, Edema	Altered Intercellular Communication	Interstitial edema, invasion of inflammatory cells, fibroelastosis around cancer cells, proliferous intima, thrombus and inflammation of vessels were also found at the same sites.	11829852
Primary sclerosing cholangitis, Inflammation, Bile Ducts, Extrahepatic	Altered Intercellular Communication	Primary sclerosing cholangitis is characterized by progressive fibrotic inflammation and obliteration of intra- and/or extrahepatic bile ducts.	11830325
Inflammation	Altered Intercellular Communication	Joint inflammation was evaluated by active joint count, functional status by Health Assessment Questionnaire (HAQ), and radiographic findings in hands and feet by the Larsen method.	11830430
Inflammation, Fibrosis Assessment, Hemorrhage	Altered Intercellular Communication	Findings of the resected specimens showed severe inflammation, fibrosis, and bleeding in the gallbladder wall with infiltration by many foamy cells.	11830932
Inflammation, Dissection of aorta	Altered Intercellular Communication	Usefulness of indium-111-oxine-labeled leukocyte scintigraphy in diagnosis of inflammation associated with chronic aortic dissection.	11831401
Inflammation, Dissection of aorta	Altered Intercellular Communication	Indium-111-oxine-labeled leukocyte scintigraphy may be a useful noninvasive technique to assess the persistent inflammation in patients with chronic aortic dissection.	11831401
Interstitial Cystitis, Cystitis	Altered Intercellular Communication	Little attention has focused on systemic factors that may allow a state of chronic bladder inflammation to be established and maintained in interstitial cystitis cases.	11832727
Inflammation, Injury wounds, Atrophic	Altered Intercellular Communication	Acute, subacute or chronic inflammatory changes, and fibrous membrane formation were observed in well-closed corneal wounds, whereas inflammation, atrophy and scar were observed in the focal tissues.	11834147
Inflammation, Infiltration	Altered Intercellular Communication	Severe inflammation was observed in the anterior segmental tissues with fibrous infiltration in the anterior chamber, which might result in rapid destruction of the eyeballs.	11834147
Inflammation, Carcinoma, Transitional Cell	Altered Intercellular Communication	In the 46 patients, 42 cases of urothelial carcinoma and 4 cases of nonspecific inflammation were diagnosed.	11834388
Communicable Diseases, Inflammation, idarubicin	Altered Intercellular Communication	sTfR levels were elevated (>28.1 nmol/L) in 68% of the IDA patients but also in 43% of the patients with ACD-chronic inflammation and 33% with ACD-acute infection.	11835323
Inflammation	Altered Intercellular Communication	Our data show that inhibition of NF-kappaB by PDTC markedly reduces inflammation, iNOS expression in the dTGR most likely leading to decreased cytotoxicity, and cell proliferation.	11835691
Inflammation, Observation Method - Coagulation, Coronary Arteriosclerosis, Depression, CTCAE	Altered Intercellular Communication	Inflammation and coagulation factors in persons > 65 years of age with symptoms of depression but without evidence of myocardial ischemia.	11835923
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Thus, depression and exhaustion are associated with low-grade inflammation and elevated coagulation factors in persons aged > 65 years.	11835923
Epithelial tumor of ovary, Neoplasms	Altered Intercellular Communication	The ability of ovarian epithelial tumour cells to secrete 17 beta-estradiol suggests that epithelial ovarian tumours play an active role in altering their own hormonal environment, promoting tumour progression.	11836573
Inflammation, Dysplasia, Intraepithelial Neoplasia	Altered Intercellular Communication	These findings indicated that HSP27 expression seems to protect cells from apoptosis during inflammation, while the down-regulation in dysplasia could impair the protective mechanism against mutagenesis induced by environmental factors and thus enhancing the transformation of oral epithelial dysplasia into OSCCs.	11836590
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The Mayo risk score did not change significantly, and no significant changes were noted in the degree of inflammation, fibrosis, histologic stage of disease, or cholangiographic findings at the end of the treatment period.	11837718
Proteinuria, Inflammation	Altered Intercellular Communication	A positive culture of tuberculous bacilli led anti-tuberculous drugs resulted in the complete disappearance of proteinuria, inflammation, and various organ manifestations.	11837803
Inflammation, Mast cell infiltration, Carcinoid Tumor	Altered Intercellular Communication	Carcinoid plaques were also involved by neovascularization (94% [131/139]), chronic inflammation (94% [131/139]), and mast cell infiltration (64% [89/139]).	11838647
Branchioma, Inflammation	Altered Intercellular Communication	Changes in the epithelium of Rathke cleft cyst associated with inflammation.	11838792
Inflammation	Altered Intercellular Communication	Inflammation was classified as acute, subacute, chronic, or end stage.	11838792
Inflammation	Altered Intercellular Communication	Inflammation had penetrated the cyst epithelium or subjacent stroma in 10 patients, and the stage of inflammation correlated well with the type of epithelia group: early stages of inflammation in the single epithelium group and chronic or end-stage inflammation in the stratified epithelia (p = 0.0027).	11838792
Refractory Cytopenia of Childhood, Inflammation, Pituitary Gland, Panhypopituitarism	Altered Intercellular Communication	Epithelial stratification in the RCC is caused by inflammation that may extend into the adjacent adenohypophysis or neurohypophysis and overwhelm the hypophysis, resulting in panhypopituitarism.	11838792
Inflammation, Thrombosis, Dental Plaque	Altered Intercellular Communication	In addition to lowering lipids, statins favorably affect platelet adhesion, thrombosis, endothelial function, inflammation, and plaque stability, which may potentially improve outcome after percutaneous coronary intervention (PCI).	11839623
Inflammation, Bone Marrow Diseases, Acquired Immunodeficiency Syndrome, Damage, V-Series Nerve Agent VM	Altered Intercellular Communication	To investigate axonal pathologic changes in vacuolar myelopathy (VM), semiquantitative immunohistochemical stains for inflammation, axonal damage, and gliosis were performed on spinal cord sections from patients with AIDS with and without VM and from HIV-negative controls.	11839857
Inflammation, Damage, V-Series Nerve Agent VM	Altered Intercellular Communication	Significant axonal damage was present in only moderate to severe VM, despite inflammation at all stages.	11839857
Refractory anemias, Inflammation	Altered Intercellular Communication	Dynamic gadolinium-enhanced magnetic resonance imaging (DEMRI) is a sensitive technique for the detection of synovial inflammation in RA.	11840438
Inflammation, Thrombosis, Mastoiditis	Altered Intercellular Communication	Thrombosis of the sigmoid sinus following mastoiditis is a rare but severe complication of middle ear inflammation.	11840797
Suppurative inflammation	Altered Intercellular Communication	None of the patients had purulent inflammation or was treated with antibacterial drugs.	11840809
Fibrosis Assessment, Hepatitis, Liver diseases	Altered Intercellular Communication	[Cytokine regulation of liver inflammation and fibrosis during chronic hepatic diseases].	11840829
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	These data are in line with experimental findings, indicating an important role of the studied cytokines in the development of hepatic inflammation, fibrosis, and cytopenic syndromes.	11840829
Inflammation, Rosacea	Altered Intercellular Communication	Chronic inflammation is believed to account for some symptoms of rosacea.	11841193
Venous Thrombosis, Thrombosis, Inflammation	Altered Intercellular Communication	Interleukin 8 and venous thrombosis: evidence for a role of inflammation in thrombosis.	11841414
Hormone abnormality, Disease, McCune-Albright Syndrome, Fibrous Dysplasia	Altered Intercellular Communication	McCune-Albright syndrome is a rare disorder caused by an activating mutation of the alpha subunit of the Gs protein and is characterized by multiple hormonal abnormalities, fibrous dysplasia of bone, and cutaneous pigmentation.	11841638
Refractory anemias, Rheumatoid Arthritis, Inflammation, Joints	Altered Intercellular Communication	There is no doubt that oxidative stress occurs in patients with rheumatoid arthritis (RA) and play an important role in both inflammation and destruction of RA joints.	11841836
Inflammation, Disease remission	Altered Intercellular Communication	In addition, markers of inflammation and acute-phase reactants were measured in order to compare activity during active disease and during remission.	11843038
Acute and chronic inflammation	Altered Intercellular Communication	Phenols have a direct toxic effect on human colonic epithelial cells in vitro, which supports the view that dietary fermentation metabolites may be involved in the modulation of chronic bowel inflammation.	11843040
Inflammation, Lung Diseases, Interstitial	Altered Intercellular Communication	Interstitial lung diseases (ILD) are characterized by an acute or chronic inflammation of the alveolar capillary membrane, which affects the permeability of this membrane.	11843324
Inflammation, Gastritis, Atrophic	Altered Intercellular Communication	The African enigma: low prevalence of gastric atrophy, high prevalence of chronic inflammation in West African adults and children.	11843957
Inflammation	Altered Intercellular Communication	Both adults (n = 45) and children (n = 37) mainly demonstrated chronic mild antral inflammation.	11843957
Inflammation	Altered Intercellular Communication	Adults tended to demonstrate more frequent acute (AI) and chronic inflammation (CI) (38% compared with 18% and 85% compared with 72%, respectively).	11843957
Granuloma, Fibrosis Assessment, Acute and chronic inflammation, Necrosis	Altered Intercellular Communication	Surgical specimens revealed noninfectious chronic inflammation, granuloma formation, and fibrosis or necrosis.	11844237
Inflammation, Ear discharge, Chronic otitis	Altered Intercellular Communication	Apparently the cause is a chronic inflammation (or chronic ekzema) of the medial part of the external meatus or also a long-lasting otorrhea in chronic otitis media.	11845396
Asthma, Respiratory distress, Wheezing, Upper Respiratory Infections	Altered Intercellular Communication	To elucidate respiratory inflammation among these children, we measured the levels of eosinophil cationic protein (ECP) and tryptase in sputum taken from three different groups of wheezy infants and young children: those with a first wheeze (n = 15); those with recurrent wheeze (n = 27); and those with recurrent wheeze with respiratory distress, namely asthma (n = 56).	11846869
Hyperlipidemia, Thrombosis, Inflammation, Diabetes Mellitus, Fibrinogen in blood above reference range, Hypertension, CTCAE	Altered Intercellular Communication	Risk factors for atherothrombosis including increased leukocyte count, hyperlipidemia, diabetes mellitus, hypertension as well as smoldering inflammation and hyperfibrinogenemia might affect the aggregability of peripheral blood erythrocytes, leukocytes as well as platelets.	11847419
Adrenal cortical hypofunction	Altered Intercellular Communication	We describe a boy, 10 years and 5 months old, who developed acute adrenal gland insufficiency which was confirmed by hormonal investigation.	11847478
Sarcoma, Inflammation	Altered Intercellular Communication	Pathology revealed 11 primary LS, 14 locally recurrent LS, 5 other sarcomas, 1 inflammation, 1 lymphoma and 10 benign lesions.	11848531
Sarcoma, Inflammation, Lymphoma, Neoplasms	Altered Intercellular Communication	Primary LS were distinguishable from benign tumors, while other sarcomas, inflammation and lymphoma were not.	11848531
Inflammation, Laryngeal Squamous Cell Carcinoma	Altered Intercellular Communication	Alterations in host immunity, inflammation, angiogenesis and metabolism are all prominent clinical features in patients with laryngeal squamous cell carcinoma (LSCC).	11848533
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	Sources of inflammation other than CAD, PVD and clinically obvious INF-INFL in peritoneal dialysis patients remain to be identified.	11849404
Communicable Diseases, Inflammation, Coronary heart disease	Altered Intercellular Communication	Parameters of inflammation and infection in a community based case-control study of coronary heart disease.	11849671
Inflammation	Altered Intercellular Communication	High sensitivity CRP, a marker of inflammation, predicts risk of cardiovascular events.	11849862
Airway structure	Altered Intercellular Communication	Study of this phenomenon has revealed multiple mechanisms and contributed to understanding of the increase in airway inflammation and bronchoconstriction observed in this context.	11851543
Renal Cell Carcinoma Pathway, Hypercalcemia	Altered Intercellular Communication	Higher expression of K-ras is associated with parathyroid hormone-related protein-induced hypercalcaemia in renal cell carcinoma.	11851621
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Further adjustment for classical cardiovascular risk factors or indicators of (sub)clinical atherosclerosis, endothelial dysfunction, inflammation and renal function did not materially alter this relative risk.	11851720
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Classical cardiovascular risk factors (sub)clinical atherosclerosis, endothelial dysfunction and inflammation do not explain this excess risk.	11851720
Inflammation, Stenosis, Intrahepatic bile duct	Altered Intercellular Communication	Endoscopic results showed dilation of the intrahepatic bile ducts, radiation-induced inflammation and narrowing of the antrum and the duodenum, and stricture of the papilla and the last few millimeters of the common bile duct.	11852395
Virus Diseases, Acute asthma	Altered Intercellular Communication	Virus infection and acute asthma is associated with neutrophilic inflammation, cell lysis and more severe clinical disease.	11852895
Inflammation, Pain Distress Question	Altered Intercellular Communication	Elevated levels of these neuropeptides in pulps from painful teeth indicate that they may play an important role in the process of pulpal inflammation and pain.	11853236
Inflammation, Pain Distress Question	Altered Intercellular Communication	Further investigation of the association between these neuropeptides and pulpal status may help to improve our understanding of pulpal inflammation and dental pain.	11853236
Keratitis	Altered Intercellular Communication	There were 2 cases with recurrence of corneal inflammation, and the lesion was controlled by penetrating keratoplasty.	11853575
Keratitis, Glaucoma, CTCAE	Altered Intercellular Communication	The penetrating keratoplasty group included 31 cases, of them, 27 cases were cured with one surgery and 4 eyes were enucleated due to recurrent corneal inflammation or refractive glaucoma.	11853575
Necrotizing granulomatous inflammation	Altered Intercellular Communication	MICROSCOPIC DATA: Histological analysis of endoscopical and surgical intestinal specimens showed chronic granulomatous inflammation of the ileum, colon, and rectum, confirming the diagnosis of CD.	11854608
Inflammation, Atherosclerosis, alcohol and other drug (AOD) thesaurus, Aortic Aneurysm, Abdominal, Arterial Occlusive Diseases, APP gene	Altered Intercellular Communication	Inflammation and atherosclerosis are present in both abdominal aortic aneurysm (AAA) and arterial occlusive disease (AOD).	11854734
Asthmatic Airway Remodeling	Altered Intercellular Communication	The lymphocyte predominance in the present case therefore suggests a distinct etiology rather than asthmatic airway inflammation.	11855082
Inflammation	Altered Intercellular Communication	Decrease of ABC reflects a later than erythrocyte sedimentation rate and acute phase proteins normalization of metabolic consequences of inflammation.	11855337
Inflammation, Traumatic injury	Altered Intercellular Communication	Serum amyloid A (SAA) is an early and sensitive marker of the extent of tissue trauma and inflammation.	11856128
Inflammation, Hepatitis, Liver Cirrhosis	Altered Intercellular Communication	In the liver tissues of chronic hepatitis and liver cirrhosis, PDGF and its receptor and alpha-SMA mainly distributed in the fibrotic septa and the infiltration area of inflammation, particularly in branch spindle-shaped cells (activated HSC).	11856507
Communicable Diseases, Inflammation	Altered Intercellular Communication	Is soft-tissue inflammation in pedal infection contained by fascial planes?	11856683
Communicable Diseases, Inflammation	Altered Intercellular Communication	The purpose of this study was to analyze compartmental involvement and patterns of spread of soft-tissue inflammation in pedal infection.	11856683
Inflammation, Infection	Altered Intercellular Communication	Inflammation from toe infections spread in 34% of cases to forefoot compartments (15/44).	11856683
Inflammation, Infection	Altered Intercellular Communication	Inflammation from forefoot or toe infections spread in 4.5% of cases to the midfoot and in 2% of cases to the hindfoot; ascension into the calf was rare (1% of cases).	11856683
Osteomyelitis, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Spread of inflammation into neighboring compartments was not correlated with the presence of diabetes (p = 0.81) or with osteomyelitis (p = 0.34).	11856683
Inflammation, Edema	Altered Intercellular Communication	In 4 patients endoscopy of the upper GI-tract showed a severe inflammation (n = 1) and a fibrinopurulent exsudate, severe edema and isolated ulcerations (n = 3) of jejunum after gastrectomy or duodenum with intact stomach.	11857099
Inflammation, Anemia	Altered Intercellular Communication	Physical examination did not provide any relevant information, laboratory tests revealed an elevation of inflammation markers and anemia.	11857101
Inflammation, Intracranial Aneurysm, Aneurysm, Cerebral Atherosclerosis, Connective Tissue Diseases	Altered Intercellular Communication	Out of a series of 472 intracranial aneurysms treated over 11 years, 11 patients between the ages 16 and 67 years (mean age 37) were identified who had discrete fusiform aneurysms unassociated with generalized cerebral atherosclerosis, connective tissue disorder or inflammation.	11858533
Lupus Erythematosus, Autoimmune Disorder, CTCAE, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Systemic lupus erythematosus (SLE) is an autoimmune disorder which may be affected by hormonal changes, such as those of pregnancy.	11858886
Inflammation, Post-infectious disorder	Altered Intercellular Communication	Clinical, immunological and neuroimaging findings indicate that post-infectious immune mediated inflammation, seems the most probable pathogenetic mechanism in this case.	11859442
Inflammation, Vestibular Neuronitis, Meniere Disease	Altered Intercellular Communication	In the present series, histopathologic and radiologic changes in the vestibular ganglion and meatal ganglion were consistent with a viral inflammation of ganglion cells in cases of Meniere's disease, benign paroxysmal positional vertigo, and vestibular neuronitis.	11860061
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	We hypothesized that elastin degradation should increase as a result of increased lung inflammation during an acute exacerbation of COPD and should decrease after recovery.	11860167
Communicable Diseases, Primary malignant neoplasm, Inflammation, Anemia	Altered Intercellular Communication	Anaemia is a frequent complication of chronic inflammation, infectious diseases and cancer.	11860225
Airway structure, Coughing	Altered Intercellular Communication	Eosinophilic airway inflammation as an underlying mechanism of undiagnosed prolonged cough in primary healthcare patients.	11863210
Airway structure, Coughing	Altered Intercellular Communication	Using a simple method of sputum induction and processing of sputum samples, we determined whether eosinophilic airway inflammation could be a cause of undiagnosed prolonged cough.	11863210
Airway structure, ARCN1 gene, Asthma, Coughing	Altered Intercellular Communication	We conclude that eosinophilic airway inflammation is a fairly common cause of prolonged cough, even in patients not suffering from asthma or COPD, or in whom no other cause of cough is known to be present.	11863210
Airway structure	Altered Intercellular Communication	Detection of eosinophilic airway inflammation could aid the decision regarding treatment.	11863210
Inflammation, Choroidal Detachment	Altered Intercellular Communication	The complications such as flat chamber, inflammation and choroidal detachment were not observed.	11864436
Communicable Diseases, Inflammation	Altered Intercellular Communication	Active trachomatous inflammation and additional infection with bacteria may accelerate this process.	11864895
Inflammation, Atherosclerosis, Hypercholesterolemia, Diabetes Mellitus, Hypertension, CTCAE	Altered Intercellular Communication	Using multiple regression, sFas was found to be associated with PAOD independently of classical risk factors for atherosclerosis (hypercholesterolaemia, diabetes, hypertension, and smoking), markers of inflammation (e.g.	11865097
Inflammation, Ototoxicity, Brain Injuries, COL4A2 wt Allele	Altered Intercellular Communication	To investigate the relationship of markers of excitotoxicity and inflammation to brain injury after ICH.	11865143
Inflammation, SLC25A20 gene, Carcinoma, Dysplasia, Ulcerative Colitis, Diverticulosis, Colorectal Carcinoma	Altered Intercellular Communication	Colectomy specimens from patients with CAC, patients with ulcerative colitis (UC) and dysplasia, patients with long-standing UC without carcinoma or dysplasia, and patients with CRC were investigated in comparison to normal colon (NC) specimens from patients with diverticulosis without histologic signs of inflammation.	11865380
Intestinal metaplasia of gastric mucosa, Inflammation, Acid reflux, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Helicobacter pylori infection, not gastroesophageal reflux, is the major cause of inflammation and intestinal metaplasia of gastric cardiac mucosa.	11866266
Inflammation	Altered Intercellular Communication	The etiology of inflammation below the normal Z-line is an area of intense debate.	11866266
Intestinal metaplasia, Inflammation, Cardia of stomach, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Endoscopic biopsy specimens from the gastric cardia (obtained on retroflexed view), fundus, and antrum were evaluated for inflammation, H. pylori infection, and intestinal metaplasia.	11866266
Gastroesophageal reflux disease, Barrett Esophagus, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Inflammation of gastric cardiac mucosa decreases in prevalence from controls to patients with GERD and Barrett's esophagus and correlates strongly with H. pylori infection.	11866266
Intestinal metaplasia	Altered Intercellular Communication	Cardia intestinal metaplasia is associated with H. pylori-related cardiac inflammation and intestinal metaplasia elsewhere in the stomach.	11866266
Helicobacter-associated gastritis	Altered Intercellular Communication	Helicobacter pylori-associated inflammation is mediated, in part, by inflammatory cytokines.	11866267
Gastritis	Altered Intercellular Communication	Levels of proinflammatory cytokine mRNA are increased in acid-driven as well as infection-driven gastric inflammation, and the presence of both disease processes appears to have an additive effect on local cytokine message expression.	11866267
Inflammation, Neutrophilia (finding)	Altered Intercellular Communication	As AH is accompanied by inflammation, neutrophilia and polymorphonuclear neutrophil (PMN) infiltration of the liver, we postulated that PMN could be a source of HGF in such patients.	11867177
Inflammation, Abnormal degeneration	Altered Intercellular Communication	Inflammation, degeneration and metabolic processes were very rare.	11868243
Coughing, Inflammation, Carcinoid Tumor, Hemoptysis	Altered Intercellular Communication	When cough, weezing, hemoptysis and inflammation of lung parenchyma are prolonged, carcinoid should always be considered in differential diagnosis.	11868252
Inflammation, Neoplasms	Altered Intercellular Communication	Five primary reasons for the delays in group A were identified: 1) Four patients were tentatively diagnosed as inflammation or benign tumor on CT and were consequently not followed-up.	11868615
Inflammation, Neoplasms	Altered Intercellular Communication	3) Four patients were tentatively diagnosed as inflammation or benign tumor on CT, but the tumors showed only very slow growth or no change at all.	11868615
Inflammation, Bronchoconstriction, Chronic disease	Altered Intercellular Communication	Asthma is a chronic disease characterized by inflammation and bronchoconstriction.	11868930
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	To determine the nature and origin of synovial inflammation in knees with osteoarthritis (OA).	11869075
Inflammation, Neoplasms	Altered Intercellular Communication	In 74 of 94 patients a solid tumor or an inflammation of the pancreas ( n=62) or the papilla ( n=12) was detected.	11870425
Inflammation, Adenoma, Carcinoma, Gallbladder Carcinoma	Altered Intercellular Communication	Other pathologic findings included adenoma or inflammation of the duodenum ( n=5), carcinoma or benign stenosis of the choledochus duct ( n=7) and carcinoma of the gall bladder ( n=2).	11870425
Inflammation, Leukocytosis, Neutrophilia (finding)	Altered Intercellular Communication	Laboratory findings showed a chronic to acute inflammation with leukocytosis, granulocytosis in the differential blood count, raised C-reactive protein in a range from 54.7 to a maximum of 157.2 mg/l and a protein electrophoresis with elevated alpha1- and alpha2-fraction.	11870558
Idiopathic Inflammatory Myopathies, Balanitis circumscripta plasmacellularis	Altered Intercellular Communication	Zoon's balanitis (ZB) is an uncommon, benign, idiopathic inflammatory condition affecting uncircumcised males.	11870791
Crohn Disease	Altered Intercellular Communication	Mutations in CARD15 have recently been found in patients with Crohn disease (CD), a chronic inflammatory condition of the digestive tract.	11875755
Inflammation, Neuralgia	Altered Intercellular Communication	Inclusion criteria were a normal or near normal neuropathic foot, without signs of inflammation.	11875766
Inflammation, Herpetic whitlow	Altered Intercellular Communication	Instead of herpetic changes, mild inflammation was evident.	11876004
Follicle, Inflammation, Keratosis pilaris, Atrophic	Altered Intercellular Communication	Keratosis pilaris atrophicans faciei (KPAF), previously called ulerythema ophryogenes, belongs to a group of follicular syndromes with inflammation and atrophy.	11876014
Follicle, Inflammation, Atrophic	Altered Intercellular Communication	Follicular syndrome with inflammation and atrophy starts in early childhood, but first lesions can also appear among teenagers or in adults.	11876014
Gastritis	Altered Intercellular Communication	This study shows that, in ABG-S+ patients after eradication treatment, serology does not keep in step with gastric inflammation.	11876704
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	However, a significant improvement occurred in the mean histological scores of inflammation (from 2.2 to 0.5), atrophy (from 2.2 to 1.2) and intestinal metaplasia (from 1.6 to 1.1) in the corpus mucosa after H. pylori eradication.	11876705
Intracapsular cataract extraction, Inflammatory abnormality of the eye	Altered Intercellular Communication	TWP is effective in reducing postoperative anterior ocular inflammation after extracapsular cataract extraction and IOL implantation.	11877218
Airway structure, Fibrosis Assessment, Bronchiectasis	Altered Intercellular Communication	Therefore, defective airway clearance of apoptotic cells in cystic fibrosis and bronchiectasis may be due to elastase-mediated cleavage of phosphatidylserine receptor on phagocytes and may contribute to ongoing airway inflammation.	11877474
Inflammation, Swelling, Calcium pyrophosphate deposition disease	Altered Intercellular Communication	Two potential mechanisms might have been responsible for the persistent swelling: (1) chondrocalcinosis led to effusion of a suprapatellar pouch that was originally isolated from the knee joint cavity, or (2) the suprapatellar pouch was separated from the knee joint cavity as a result of an incomplete involuted suprapatellar plica that became adherent during recurrent inflammation due to chondrocalcinosis.	11877632
Inflammation, Hypertension, CTCAE, Microcirculatory Bed, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	To examine the association between retinal arteriolar narrowing, a marker of microvascular damage from hypertension and inflammation, and incident CHD in healthy middle-aged women and men.	11879113
Inflammatory abnormality of the eye	Altered Intercellular Communication	Reducing ocular surface inflammation might have an effect on the proliferative activity of the epithelium.	11879137
Inflammation, Hypergammaglobulinemia, Thickened, Peripheral Blood Eosinophilia, Unknown (origin) (qualifier value), Eosinophilic Fasciitis	Altered Intercellular Communication	Eosinophilic fasciiitis is an idiopathic and uncommon condition, a scleroderma-like disorder that predominantly affects the extremities and is characterized by marked thickening and inflammation of the fascia, associated with with peripheral blood eosinophilia, hypergammaglobulinemia, and characteristic histologic findings.	11879585
Chrysosporium zonatum, allergic inflammation	Altered Intercellular Communication	Pulmonary colonization by Chrysosporium zonatum associated with allergic inflammation in an immunocompetent subject.	11880456
MTA2 gene, Pelvic Inflammatory Disease, Endometriosis	Altered Intercellular Communication	In women treated for PID, pelvic inflammation was found in 25.8%, but in 22.5% the finding was negative and in 20.2% the endometriosis was diagnosed.	11881281
Adenolymphoma, Inflammation, Histogenic Process, Necrosis	Altered Intercellular Communication	Although the histogenesis of lymphoid components of Warthin's tumor is controversial, the frequent prevalence of inflammation or necrosis and our present findings suggest these components have a similar behavior to regional lymph nodes.	11881733
Inflammation, Autoimmune Diseases, Communicable Diseases, Chlamydia, Heat-Shock Response	Altered Intercellular Communication	Autoimmunity to human heat shock protein 60, Chlamydia pneumoniae infection, and inflammation in predicting coronary risk.	11884286
Communicable Diseases, Inflammation, HSPD1 wt Allele	Altered Intercellular Communication	Our aim was to study the role of Hsp60 antibodies as coronary risk predictors and their association with C pneumoniae infection and inflammation.	11884286
Communicable Diseases, Inflammation, immunoglobulin A	Altered Intercellular Communication	In conclusion, an elevated human Hsp60 IgA antibody level was a risk factor for coronary events, especially when it was present together with C pneumoniae infection and inflammation.	11884286
Inflammation	Altered Intercellular Communication	These data suggest that BabA facilitates colonization of H. pylori and thereby increases IL-8 response, resulting in enhanced mucosal inflammation.	11884476
Inflammation, Hemorrhage, Congestion	Altered Intercellular Communication	Light microscopy observation revealed alterations in predentine, calcium deposition, fibrohyalinosis, congestion, inflammation and haemorrhage.	11885454
Inflammation, Cachexia, Anorexia	Altered Intercellular Communication	Inflammation has been associated with cachexia and anorexia.	11887811
palladium, Inflammation, Malnutrition, Anorexia	Altered Intercellular Communication	Infection with HP is associated with anorexia, inflammation, and malnutrition in PD patients.	11887811
palladium, Inflammation, Malnutrition	Altered Intercellular Communication	The present study supports the hypothesis of the involvement of inflammation in the pathogenesis of malnutrition in PD patients.	11887811
Inflammation, Esophagitis	Altered Intercellular Communication	In oesophagitis, endoscopic and histopathological grades of inflammation correlated highly.	11889061
Barrett Esophagus, Inflammation	Altered Intercellular Communication	In Barrett's oesophagus, 29/50 had no endoscopic evidence of inflammation and histopathological inflammation was mild in 17/50 and moderate in 24/50, independent of acid suppressants.	11889061
Proctitis, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Human neutrophil lipocalin is a unique marker of neutrophil inflammation in ulcerative colitis and proctitis.	11889070
Inflammation, Primary malignant neoplasm, Thyroid carcinoma, Hashimoto Disease, Malignant Neoplasms	Altered Intercellular Communication	Because of its dual role in inflammation and cancer, we were interested in determining if COX-2 plays a role in the development of human thyroid carcinoma and Hashimoto's thyroiditis, an autoimmune condition frequently associated with thyroid malignancy.	11889377
Pain Distress Question, Inflammation, Abnormal color, Communicable Diseases, Granulation finding, Exudate, Edema, Erythema	Altered Intercellular Communication	The Clinical Signs and Symptoms Checklist delineates 12 signs and symptoms of infection (i.e., pain, erythema, edema, heat, purulent exudate, serous exudate with concurrent inflammation, delayed healing, discoloration of granulation tissue, friable granulation tissue, pocketing at the base of the wound, foul odor, and wound breakdown) and their definitions.	11889655
Inflammation, Raynaud Phenomenon	Altered Intercellular Communication	PSS was kept in a relatively good condition before onset of his surgical disease, but his Raynaud's phenomenon was much worse and inflammation findings were very severe before his operation.	11889789
Myocarditis, Pulmonary Hypertension, Fibrosis Assessment, Cardiac complication, KANTR gene, Heart failure, Cardiac Arrhythmia	Altered Intercellular Communication	PSS has many cardiac complications, for example spasm or organic changes of coronary artery, cardiac fibrosis, arrhythmia, secondary cardiac failure of pulmonary hypertension, pericardial inflammation, and so on, but we speculate that LOS might be caused by peripheral vessel disturbance.	11889789
Inflammation	Altered Intercellular Communication	Biopsy of the nonresectable mass revealed the presence of chronic inflammation in the mesenteric area with Actinomyces colonies.	11890342
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	Pulmonary rheumatoid nodules show morphologic features reminiscent of a necrotizing inflammation of rheumatoid synovitis and differ from subcutaneous rheumatoid nodules only by their location, extension, and size.	11892018
Inflammation, Carcinogenesis	Altered Intercellular Communication	These findings suggest that in colon-rectum cancer, the pathologic event induces an increased expression of the molecules involved in the processes of inflammation and carcinogenesis that occurs earlier than the appearance of morphologic modifications.	11893036
Inflammation	Altered Intercellular Communication	CT scan highlighted a 6 cm para-laryngeal mass, of mixed attenuation, with an adjacent region of inflammation.	11893462
Inflammation	Altered Intercellular Communication	The relationship between complement activation and inflammation in mature females differs from that in the other groups, suggesting mediators of the response may change with age and gender.	11893855
Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is a chronic inflammatory condition, manifest in its early stages by endothelial dysfunction.	11895465
Inflammation, Periodontal Diseases	Altered Intercellular Communication	Release of IL-8 and TNF-alpha from peripheral neutrophils and various parameters of inflammation in plasma seem to be affected more by cigarette smoking than periodontal disease.	11895539
Inflammation	Altered Intercellular Communication	In 10 patients H. pylori was not detected, but inflammation was present.	11895551
Airway structure, Inflammation, Airway Obstruction	Altered Intercellular Communication	Affected patients suffer from chronic sputum production and usually slowly progressive airway destruction as a result of continued airway infection and inflammation.	11896905
Communicable Diseases, Inflammation, Edema	Altered Intercellular Communication	Other therapies include treatment of associated infection, treatment for edema and inflammation, and debridement when necessary.	11896977
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Because oxidative stress and inflammation are believed to play roles in the pathogenesis of cardiovascular diseases, oxidative stress in polymorphonuclear leukocytes (PMNs) and mononuclear cells (MNCs) has been measured.	11897762
Mediastinitis	Altered Intercellular Communication	The majority of benign BEF in adults are acquired, and result from mediastinal inflammation.	11899200
Inflammation, Angina, Unstable	Altered Intercellular Communication	Recent data show that markers of inflammation, endothelial perturbation as well as activation of the coagulation and fibrinolytic systems are altered in unstable angina.	11899586
APP gene, Communicable Diseases, Inflammation	Altered Intercellular Communication	Since all patients in this group were diagnosed as having symptomatic AAA, we suggest that active infection can exacerbate inflammation in the AAA wall and accelerate progression of the disease.	11899845
Myocarditis, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Local expression of interleukin-1 receptor antagonist by plasmid DNA improves mortality and decreases myocardial inflammation in experimental coxsackieviral myocarditis.	11901035
Fibrosis Assessment, Myocarditis	Altered Intercellular Communication	Myocardial inflammation on day 7 and fibrosis on day 14 were markedly decreased in IL-1Ra-CVB3.	11901035
Microalbuminuria, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	C-reactive protein (CRP) and microalbuminuria are nowadays considered markers of chronic inflammation of the arterial wall and of endothelial dysfunction, respectively.	11902818
Inflammation, Endothelial dysfunction, Overweight, Atherosclerosis	Altered Intercellular Communication	On this basis, it can be argued that inflammation of the arterial wall, as indicated by higher CRP plasma levels, and endothelial dysfunction, as shown by higher UAE rate, might represent simultaneous phenomena in the development of atherosclerosis in overweight and obese premenopausal women.	11902818
vascular inflammations, Vasculitis, CTCAE, Sweet Syndrome	Altered Intercellular Communication	Vascular inflammation (vasculitis) in sweet syndrome: a clinicopathologic study of 28 biopsy specimens from 21 patients.	11902985
Inflammation, Brain Injuries	Altered Intercellular Communication	Data from experimental studies indicate that acute inflammation contributes to ischaemic brain damage.	11903929
Mucous Membrane, Inflammation, Neoplasms	Altered Intercellular Communication	Mucosal injury may be involved in the progression to neoplasia via the synthesis of prostaglandins and other mediators of inflammation.	11904314
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	We wanted to distinguish wall thickening caused by cancer extension from that caused by inflammation after placing a biliary catheter on intraductal ultrasonography (IDUS).	11907728
Inflammation, Ulcer	Altered Intercellular Communication	Since they are involved in coagulation, inflammation (enhancing of adhesion molecules and tissue lysis) and apoptosis of endothelial cells, their significance in chronic ulcers, both as a consequence and/or possible cofactor merits discussion.	11908131
Pain Distress Question, Inflammation, Infection of bone	Altered Intercellular Communication	In our observation, the leg pain which preceded other signs of local inflammation, suggested the existence of primitive bone infection which further diffused in soft tissues, thus explaining the erysipelatoid aspect.	11908169
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Norepinephrine from synovial tyrosine hydroxylase positive cells is a strong indicator of synovial inflammation in rheumatoid arthritis.	11908553
Inflammation	Altered Intercellular Communication	We investigated the role of TH+ cells and NE in synovial inflammation.	11908553
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	Basal NE release correlated with the degree of inflammation in RA (Rrank = 0.420, p = 0.021) but not in OA (Rrank = 0.174, NS), and with spontaneous IL-8 secretion in RA (Rrank = 0.581, p = 0.001) but not in OA (Rrank = 0.160, NS).	11908553
Inflammation	Altered Intercellular Communication	TH+ cells and release of NE are strongly linked to a higher degree of synovial inflammation.	11908553
Inflammation	Altered Intercellular Communication	NE secretion of TH+ cells may be an antiinflammatory mechanism to counteract local inflammation.	11908553
Inflammation	Altered Intercellular Communication	Thus, TH+ cell derived NE can be an important local factor of immunomodulation in synovial inflammation.	11908553
Inflammation	Altered Intercellular Communication	There is no association to disease activity or other markers of disease or inflammation.	11908560
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	The development of SpA was analyzed with regard to the presence of HLA-B27, duration of IBD symptoms, and the extent of intestinal inflammation.	11908564
Gastrointestinal inflammation	Altered Intercellular Communication	No correlation between localization or extent of the intestinal inflammation and presence of AS was found.	11908564
Arteritis	Altered Intercellular Communication	However, whether the cytokine production of vessels with arteritis differs from that of vessels exposed to inflammatory conditions that originate peripheral to the vessel remains unknown.	11909890
Inflammation, Fibrosis Assessment, Infiltration	Altered Intercellular Communication	The degree of clinical retraction in millimeters did not correlate with fibrosis, inflammation, or fat infiltration.	11910320
Inflammation, Fibrosis Assessment, Thyroid associated opthalmopathies	Altered Intercellular Communication	Contrary to previous reports, the Mueller muscle is involved in the inflammation and fibrosis that characterizes thyroid-associated orbitopathy.	11910320
Aggressive behavior, Central neuroblastoma	Altered Intercellular Communication	Hormonal activity may predict aggressive behavior in neuroblastoma.	11910515
Inflammation	Altered Intercellular Communication	Chemokines might play a critical role in promoting leucocyte entry into the nervous system during immune-mediated inflammation.	11912115
Inflammation, Prostate carcinoma, Benign prostatic hypertrophy	Altered Intercellular Communication	Pathological study showed prostate cancer in 13 cases (25.5%), chronic inflammation in 37 (72.5%) and only benign prostatic hypertrophy in 1 (1.05%).	11912396
Inflammation	Altered Intercellular Communication	After left ophthalmectomy, inflammation recurred after cessation of antibiotic administration.	11912952
Sepsis, Pigmented Paravenous Chorioretinal Atrophy, Degenerative disorder, Inflammation	Altered Intercellular Communication	This is a report of the findings in pigmented paravenous retinochoroidal atrophy that is a nonspecific degenerative disease and may occur in association with systemic infections or inflammation.	11913895
Macular Edema, Cystoid, Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation with cystoid macular edema is an unusual manifestation of the disease.	11913895
Inflammation, Acute Coronary Syndrome, Nonstress test	Altered Intercellular Communication	Inflammation and long-term mortality after non-ST elevation acute coronary syndrome treated with a very early invasive strategy in 1042 consecutive patients.	11914246
Inflammation, Myocardial Ischemia, Atherosclerosis	Altered Intercellular Communication	Peroxisome proliferator-activated receptor alpha (PPARalpha) regulates the expression of genes involved in lipid metabolism and inflammation, making it a candidate gene for atherosclerosis and ischemic heart disease (IHD).	11914252
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Short-term preoperative irradiation therapy generally induced severe mucosal inflammation characterized by increased cellularity of the lamina propria, prominent eosinophilic infiltrates, crypt disarray, surface and crypt epithelial damage, nuclear abnormalities, and presence of apoptotic bodies in the crypt epithelium.	11914629
Inflammation	Altered Intercellular Communication	Despite acute severe inflammation, none of the patients treated by short-term irradiation developed perioperative complications.	11914629
Inflammation	Altered Intercellular Communication	Xerostomy (38.5 %) is usually present (in 88,9 % of all cases) before or at clinical onset of gland inflammation, whereas xerophthalmy (28.4 %) did not show such a correlation.	11914948
Granulomatous inflammation, Eosinophilic inflammation	Altered Intercellular Communication	There was neither granulomatous inflammation nor eosinophilic infiltration.	11915861
Inflammation, Asthma	Altered Intercellular Communication	Platelet-activating factor (PAF), which has been implicated in the pathophysiology of inflammation in asthma, is degraded and inactivated by PAF acetylhydrolase (PAFAH).	11916011
Communicable Diseases, Inflammation	Altered Intercellular Communication	Postoperatively, the speed of reepithelialization, changes in the severity of scleral melting and inflammation, recurrence of infection, and visual acuity were documented.	11917176
Inflammation	Altered Intercellular Communication	Over the next 10 days, the eye quietened, conjunctival and scleral inflammation lessened, and the graft was well accepted.	11917181
Inflammation, Hemolytic-Uremic Syndrome	Altered Intercellular Communication	Acute inflammation in the pathogenesis of hemolytic-uremic syndrome.	11918772
Interstitial inflammation	Altered Intercellular Communication	Hemodialysis-activated granulocytes at the site of interstitial inflammation.	11920354
Inflammation	Altered Intercellular Communication	It is not known to what extent intravascular phenotypic alterations in adhesion molecule expression induced by hemodialysis influence the recruitment of granulocytes and their ability to up-regulate CD11b at the local site of inflammation in the interstitium.	11920354
Inflammation, Bulla	Altered Intercellular Communication	The two blisters were stimulated with buffer (intermediate inflammation) or autologous serum (intense inflammation).	11920354
Inflammation	Altered Intercellular Communication	At the site of intermediate inflammation, granulocytes from patients had a significantly lower capacity to mobilize CD11b compared with cells from healthy subjects (P < 0.001).	11920354
Interstitial inflammation	Altered Intercellular Communication	At the site of intense interstitial inflammation, granulocytes from patients had the capacity to mobilize the receptor and reached values close to those obtained in healthy subjects (P = 0.079).	11920354
Inflammation, Exudate	Altered Intercellular Communication	The blister exudate from patients had a similar (at time 0 and intermediate inflammation) or higher (intense inflammation; P < 0.05) capacity to up-regulate CD11b on granulocytes in vitro compared with blister exudate from healthy subjects.	11920354
Inflammation	Altered Intercellular Communication	Joints with varying levels of clinical activity of inflammation were classified as being active, moderately active, or inactive.	11920400
Inflammatory abnormality of the eye	Altered Intercellular Communication	Clinical and laboratory diagnosis of ocular inflammation syndromes are also reviewed.	11921747
Neuronal degeneration, Abnormality of mitochondrial metabolism, Immune System Diseases	Altered Intercellular Communication	The inhibition of Na+-K+ ATPase can contribute to increase in intracellular calcium and decrease in magnesium, which can result in 1) defective neurotransmitter transport mechanism, 2) neuronal degeneration and apoptosis, 3) mitochondrial dysfunction, 4) defective golgi body function and protein processing dysfunction, 5) immune dysfunction and oncogenesis.	11922232
Inflammation, Disease	Altered Intercellular Communication	Thromboxane A2 (TXA2) is an arachidonate metabolite which is considered to relate to chronic inflammation in atopic diseases characterized by elevated immunoglobulin E productivity.	11922633
Inflammation, Atherosclerosis	Altered Intercellular Communication	Adhesion molecules especially the vascular adhesion molecules also play an important role in the pathogenesis of atherosclerosis which act as markers of inflammation.	11922919
Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Plasma concentrations of alpha2-HSG decrease significantly following infection, inflammation and malignancy.	11922920
Inflammation, Granulomatous inflammation	Altered Intercellular Communication	Histological studies of biopsy specimens of all four patients showed changes compatible with chronic inflammation, with granulomatous inflammation present in three patients and acid-fast bacilli present in two.	11923335
Airway structure, Asthma, Bronchial Hyperreactivity	Altered Intercellular Communication	Airway inflammation, basement membrane thickening and bronchial hyperresponsiveness in asthma.	11923548
Airway structure, Asthma	Altered Intercellular Communication	Physiology, airway inflammation and remodelling in asthma are interrelated and improve with ICS.	11923548
Inflammation, Periodontitis	Altered Intercellular Communication	The woman has been taking Cyclosporin-A for over 13 years and has had advanced periodontitis and severe gingival swellings and gingival inflammation.	11924223
Gastritis	Altered Intercellular Communication	The key role of Helicobacter pylori (Hp) in gastric inflammations is discussed extensively in the literature.	11924227
Inflammation, Acidophil cell, Necrosis	Altered Intercellular Communication	The liver function of most cases infected with TTV alone was abnormal and the liver tissues had different pathological damage such as ballooning, acidophilia degeneration, formation of apoptosis bodies and focus of necrosis, but the inflammation in the lobule and portal area was mild.	11925609
Alzheimers Disease", Cognition Disorders	Altered Intercellular Communication	The wide-spread loss of cortical cholinergic neurotransmission associated with the cognitive deficits is of importance to the comprehension of the symptoms and the present pharmacotherapy of Alzheimer's disease.	11925775
Granulomatous inflammation	Altered Intercellular Communication	Histological examination revealed a granulomatous inflammation, with negative Ziehl-Neelsen staining.	11925802
Inflammation, Carcinoma of lung	Altered Intercellular Communication	The diagnosis rate, by disease, was 81.8% (9/11) for lung cancer, 66.7% (2/3) for metastatic lung cancer, and 77.8% (7/9) for inflammation; the overall rate being 78.3% (18/23).	11925911
Inflammation, Swelling	Altered Intercellular Communication	Elevation of the inflammatory reaction was noted, together with swelling of the glottis and inflammation of the bronchial mucosa on bronchoscopy.	11925918
Inflammation	Altered Intercellular Communication	A partial response to the anti-Mycobacterium avium subspecies paratuberculosis combination was seen in 2 patients showing complete clinical remission with mild histologic inflammation.	11926571
Esophageal tear, Rupture	Altered Intercellular Communication	In a patient with a spontaneous rupture of esophagus, the anesthetic considerations include avoidance of further aggravation of the esophageal tear, and resuscitation from a morbid inflammatory condition.	11927482
Esophageal Varices, trauma to the abdomen, Neoplasms, Ulcer	Altered Intercellular Communication	Bleeding from upper gastrointestinal parts could be caused by this syndrome, as well as by ulcers, inflammations, esophageal varices, tumours, blunt abdominal injuries, etc.	11928605
Inflammation, Chlamydia, Venous Thrombosis	Altered Intercellular Communication	Chlamydia pneumoniae, systemic inflammation and the risk of venous thrombosis.	11929685
Inflammation, Cerebral Small Vessel Diseases, Vasculitis, CTCAE, PPP3CB wt Allele	Altered Intercellular Communication	Although evidence of vasculitic and perivascular inflammation in LNB has been described in the literature, large cerebral vessel occlusive disease represents a rare finding.	11930275
Vasculitis	Altered Intercellular Communication	This association further supports that acute posterior multifocal placoid pigment epitheliopathy is caused by vasculitic inflammation of the choriocapillaris.	11931797
Inflammation, Paraneoplastic Encephalomyelitis, Neoplasm Metastasis, Malignant Neoplasms, human MUC1 protein	Altered Intercellular Communication	Pathologic examination revealed no metastasis or direct invasion of malignancy with gliosis and perivascular inflammation throughout the brainstem, indicating paraneoplastic encephalomyelitis (PEM).	11932038
Granulomatous inflammation, Infection by Cryptococcus neoformans	Altered Intercellular Communication	Pathologic examination of the masses in the LLL revealed granulomatous inflammation with cryptococcus infection.	11932223
Inflammation, Erythema, Superficial ulcer	Altered Intercellular Communication	To assess the severity of inflammation in each part of the large intestine, colonoscopic findings were categorized into four grades: grade 1, intact mucosa; grade 2, sporadic erythema and erosion; grade 3, mostly diffuse inflammation; and grade 4, diffuse, severe inflammation.	11932787
Inflammation, Hemorrhage, Hemorrhagic colitis, Communicable Diseases, Edema	Altered Intercellular Communication	The characteristic colonoscopic findings in most patients with hemorrhagic colitis due to O157 infection were as follows: 1) severe inflammation, including primarily marked edema and facile hemorrhage, and 2) inflammation predominating at the right-side colon; and 3) frequent appearance of longitudinal ulcer-like lesions.	11932787
Inflammation, Lymphoma	Altered Intercellular Communication	Type I seemed more frequently associated with inflammation, and type II was more frequently associated with lymphoma.	11934097
Infarction	Altered Intercellular Communication	Inflammation-mediated damage in progressing lacunar infarctions: a potential therapeutic target.	11935048
Inflammation, Brain Injuries, Stroke, Lacunar	Altered Intercellular Communication	These findings suggest that inflammation contributes to brain injury in lacunar stroke.	11935048
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Inflammation and stroke: the Leiden 85-Plus Study .	11935072
Inflammation	Altered Intercellular Communication	There might be a dual protection manner by defensins against fungal inflammation in infected buccal epithelia locally.	11936455
Inflammation	Altered Intercellular Communication	Gastroscopy was normal and colonoscopic biopsies showed only non-specific inflammation of the colonic mucosa and submucosa.	11936478
Inflammation, Chlamydia	Altered Intercellular Communication	No causal association between inflammation and Chlamydia pneumoniae in patients with chronic ischemic arterial disease.	11936753
Inflammation	Altered Intercellular Communication	These results suggest that no causal association exists between inflammation and C. pneumoniae.	11936753
Inflammation, Intestinal Diseases	Altered Intercellular Communication	This particular and potentially severe inflammation must be recognized and treated in order to prevent worsening of the associated bowel disease.	11938070
Scab, Acute inflammation, Traumatic injury	Altered Intercellular Communication	Fewer important crusting reactions and fewer synechiae after diode laser assisted procedures tend to prove than postoperative inflammation and surgical trauma are smaller than with ECI.	11941234
Inflammation	Altered Intercellular Communication	Laparotomy revealed a giant diverticulum of the sigmoid colon compressing adjacent structures with signs of inflammation.	11941296
Airway structure	Altered Intercellular Communication	The precise mechanism of the relationship between upper and lower airway inflammation is still a matter of debate.	11941310
Inflammation, Asthma	Altered Intercellular Communication	We hypothesized that the extent of inflammation in the nasal mucosa is related to lung function and inflammation in the bronchial mucosa in patients with severe asthma.	11941310
Adult-Onset Still Disease, Asthma, Bronchitis	Altered Intercellular Communication	The results of this study show a direct relationship between sinonasal mucosa thickness and bronchial inflammation in severe asthma, particularly in patients with adult-onset disease.	11941310
Paranasal Sinus Disorder, Bronchitis	Altered Intercellular Communication	Whether sinus disease directly affects the intensity of bronchial inflammation is still an unanswered question.	11941310
Autoimmune Diseases, Inflammation, Primary Biliary Cholangitis	Altered Intercellular Communication	Primary biliary cirrhosis (PBC) is an autoimmune disease of the liver with inflammation of small and middle-sized bile ducts.	11943414
Inflammation, Fibrosis Assessment, Tissue injury	Altered Intercellular Communication	We postulate that revascularization may promote resolution of the ongoing inflammation, preventing further tissue injury and fibrosis.	11943726
Meckel Diverticulum	Altered Intercellular Communication	[Meckel phlegmonous diverticulum concurrent with gangrenous inflammation of the vermiform process].	11944393
Subluxation of atlantoaxial joint, Torticollis	Altered Intercellular Communication	Acute torticollis due to non-traumatic atlanto-axial subluxation (AAS) is often seen in children presenting with inflammatory conditions of the upper respiratory tract and the neck.	11945189
Inflammation, Carotid Arteries, Atherosclerosis	Altered Intercellular Communication	B-mode ultrasound-detected carotid artery lesions with and without acoustic shadowing and their association with markers of inflammation and endothelial activation: the atherosclerosis risk in communities study.	11947908
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	CRP is present in atherosclerotic lesions, and there is increasing evidence that it may contribute to inflammation.	11947913
Inflammation	Altered Intercellular Communication	These data suggest that genetic and environmental determinants each importantly contribute to the vascular risk associated with inflammation.	11947917
Airway structure	Altered Intercellular Communication	However, bronchial biopsy and lung tissue may reveal iron deposits along with airway inflammation months after the aspiration.	11948075
Airway structure	Altered Intercellular Communication	Thus, IPA can be diagnosed by a triad of aspiration, airway inflammation, and iron deposits on histology even in the absence of an FB.	11948075
Inflammation, Cholelithiasis, Carcinoma, Gallbladder Carcinoma	Altered Intercellular Communication	An association of gallbladder carcinoma with cholelithiasis suggests that chronic inflammation may modulate tumorigenesis and/or progression of the carcinoma.	11948128
Inflammation, Polymyositis	Altered Intercellular Communication	Signs of inflammation were found in 26 of 36 biopsies (72%), and inflammation combined with degeneration/regeneration (i.e., histological signs of polymyositis) in 17 biopsies (47%).	11950012
Symptoms, Myositis	Altered Intercellular Communication	However, muscle symptoms are not related to histological signs of muscle inflammation.	11950012
Cytopathogenic Effect, Viral, Myositis	Altered Intercellular Communication	IBM-like findings may represent vacuolar myopathic degeneration due to previous subclinical muscle inflammation rather than a specific clinical entity.	11950012
Neurogenic Inflammation	Altered Intercellular Communication	The function of many inflammatory cells is in part regulated by neuronal cells, which may lead to so-called neurogenic inflammation.	11950024
Degenerative polyarthritis, Inflammation, Cartilage destruction	Altered Intercellular Communication	These observations suggest that Th1 cells predominate in the synovium of patients with OA, which clearly indicates that immune regulation occurs and may play critical roles in inflammation and cartilage destruction in patients with OA.	11950250
Degenerative polyarthritis, Pain Distress Question, Inflammation, gastrointestinal	Altered Intercellular Communication	Non-steroidal antiinflammatory agents are commonly used to treat pain and inflammation associated with osteoarthritis (OA), but have poor gastrointestinal (GI) tolerability.	11950252
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	We evaluated a possible interaction between statins and inflammation in 1,246 patients with angiographically diagnosed coronary artery disease.	11950425
Inflammation, senile, Data types - Address, "Alzheimers Disease	Altered Intercellular Communication	Interleukin-4 (IL4) is an anti-inflammatory cytokine that may play a role in the inflammation pathology observed surrounding senile plaques, and may also associate with Alzheimer's disease (AD) pathogenesis.	11950517
Inflammation, Unexpected Adverse Event	Altered Intercellular Communication	Leukocyte adhesion (sVCAM-1) and low-grade inflammation (CRP) are determinants of the development of elevated UAER.	11950696
Inflammation, Fibrosis Assessment, Infection	Altered Intercellular Communication	In 92.3% of children with dual infections, inflammatory activity was mild or mean, with no fibrosis in 61.5%, and persistent chronic inflammation predominant in descriptive classification (46.1%).	11951070
Granuloma, Fracture, Inflammation	Altered Intercellular Communication	The authors conclude that the diagnosis of eosinophilic granuloma should be considered if there is unusual location of apparent "fracture," a mass in the region of the fracture, lysis of bone, and recurrence of inflammation after the initial injury has subsided.	11951450
Communicable Diseases, Noncommunicable Diseases, Inflammation, Critical Illness	Altered Intercellular Communication	: In critically ill patients, severe infection and systemic inflammation due to non-infectious causes produce very similar clinical presentations, and traditional infection markers do not always differentiate these two conditions.	11952440
Communicable Diseases, Inflammation	Altered Intercellular Communication	There were no significant differences between the markers in discriminating between patients with infection or inflammation.	11952440
Communicable Diseases, Inflammation, Critical Illness	Altered Intercellular Communication	: PCT and neopterin were equally effective, although not very accurate in differentiating between infection and inflammation in critically ill patients.	11952440
Inflammation, Balanitis circumscripta plasmacellularis	Altered Intercellular Communication	It is seen in the elderly and appears to be a metaplastic change associated with severe chronic inflammation, and possibly more specifically with Zoon's balanitis.	11952863
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	[Systemic inflammation during exacerbations of chronic obstructive pulmonary disease].	11953269
ARCN1 gene, Inflammation	Altered Intercellular Communication	The results show that 1) there is evidence of systemic inflammation during exacerbation of COPD, and 2) such systemic inflammation does not appear to be influenced significantly by intravenous corticosteroid treatment.	11953269
Inflammation	Altered Intercellular Communication	Autopsy showed extensive granulomatous inflammation of the hypothalamus and adjacent structures.	11953494
Acute Lung Injury, Inflammation	Altered Intercellular Communication	A prospective study of inflammation markers in patients at risk of indirect acute lung injury.	11954822
Respiratory Distress Syndrome, Adult, Inflammation, Pancreatitis, Respiratory Distress Syndrome, Newborn, Sepsis, Acute Lung Injury	Altered Intercellular Communication	Systemic inflammation triggered by insults like sepsis and acute pancreatitis may play a role in development of indirect acute lung injury (ALI) and acute respiratory distress syndrome (ARDS).	11954822
Respiratory Distress Syndrome, Adult, Inflammation, Acute Lung Injury	Altered Intercellular Communication	Because little is known about the course of systemic inflammation on the days preceding diagnosis of ARDS, we prospectively monitored immune inflammatory status in 52 patients at risk and we assessed the presence of ALI and ARDS on day 7 after admission to the intensive care unit.	11954822
Acute Lung Injury, Inflammation, Pancreatitis	Altered Intercellular Communication	Results give credence to the view that systemic inflammation plays a role in development of ALI triggered by pancreatitis, but not in that by massive transfusion.	11954822
Inflammation	Altered Intercellular Communication	This elevation does not appear to be related to systemic inflammation, as there was no correlation with other inflammatory factors.	11954879
Airway structure, Fibrous	Altered Intercellular Communication	There were no differences in small airways inflammation and fibrous narrowing between the hypercapneic and nonhypercapneic patients, but the percent of smallest airways (airways < 0.35 mm) was significantly lower in the hypercapneic group.	11956063
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	These data suggest that the benefit of physical activity on cardiovascular disease may be at least partly a result of effects on hemostasis and inflammation.	11956120
Inflammation, prostatitis	Altered Intercellular Communication	Distribution of chronic prostatitis in radical prostatectomy specimens with up-regulation of bcl-2 in areas of inflammation.	11956490
Inflammation, prostatitis	Altered Intercellular Communication	Chronic prostatitis was identified in all 40 cases with peripheral zone inflammation in 95% and transition zone inflammation in 87.5%.	11956490
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation was associated with BPH and cancer but had a greater tendency to be associated with BPH.	11956490
Inflammation	Altered Intercellular Communication	The base was enlarged, probably because of inflammation, but was resected without any invasion of the rectum.	11956798
Inflammation, histiocytic, Crypt	Altered Intercellular Communication	Histologic hallmarks of mucosal involvement were focal or discontinuous inflammation with crypt distortion and a histiocytic and lymphocytic predominant inflammation.	11956821
Communicable Diseases, Tumor necrosis, Inflammation	Altered Intercellular Communication	A review of the literature showed that this form of presentation is rare although in the present case it is impossible to determine if testicular inflammation was due to tumor necrosis or infection from the associated hydrocele.	11957756
Heart, Coronary Arteriosclerosis, Hypertension, CTCAE, Cardiomyopathies, Primary	Altered Intercellular Communication	In the presented work a retrospective analysis has been performed with regard to 106 patients with severe heart lesion: 72 cases with ischaemic disease, 20 cases with post-inflammation heart lesion, 7 cases with hypertension and 7 cases with idiopathic congestive cardiomyopathy.	11957798
Inflammation	Altered Intercellular Communication	Abnormal or open TJs, associated with inflammation may contribute to BBB leakage in enhancing MRI lesions and may also be involved in subtle leakage in non-enhancing focal and diffuse lesions in NAWM.	11958369
Data types - Address	Altered Intercellular Communication	Local inflammatory conditions might cause accumulation and activation of T cells in the AD brain.	11958825
Inflammation, neuron death	Altered Intercellular Communication	The goal of this study was to examine the role of Abeta in the pathogenesis of local inflammation and neuronal cell death.	11958858
Inflammation	Altered Intercellular Communication	Our results suggest Th1 immune activation in patients with HAM/TSP, which leads to chronic inflammation in the spinal cord, mediated by dysregulation of the IL-12/IL-12R axis rather than of the CD40/CD40L interaction.	11959151
Acute Coronary Syndrome, Inflammation, Injury of cardiac valve	Altered Intercellular Communication	In patients with acute coronary syndrome an increased inflammation and cardiac injury seem to coexist and correlate.	11959383
Inflammation, Musculoskeletal Pain	Altered Intercellular Communication	In the present study, we investigated the role of prolactin (PRL) in relation to the number of typical symptoms and serum markers of systemic inflammation in patients with polymyalgia rheumatica (PMR).	11961173
Pain Distress Question, Fibromyalgia	Altered Intercellular Communication	The observation of higher rates of chronic widespread pain, the cardinal feature of fibromyalgia, in women has led to hypotheses about the role of sex hormonal factors in the aetiology of symptoms.	11961178
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Laparoscopic dissection was difficult because of acute inflammation in four patients and fibrosis in two patients.	11961648
Inflammation, Fibrosis Assessment, Traumatic injury	Altered Intercellular Communication	Difficulties in laparoscopic dissection because of severe inflammation or fibrosis resulted in injuries to our patients.	11961648
Airway structure, Inflammation, Bronchospasm	Altered Intercellular Communication	It works against the inflammation, bronchospasm and airway oedema caused by leukotrienes.	11961976
Inflammation, Edema	Altered Intercellular Communication	Efficacy was assessed by measurements of visual acuity and a decrease in inflammation and macular edema on fluorescein angiograms.	11965114
Macular Edema, Cystoid	Altered Intercellular Communication	Inflammation on fluorescein angiography improved in 17 patients (81%) and cystoid macular edema decreased in 65% of the cases.	11965114
Ocular Cicatricial Pemphigoid, Conjunctivitis	Altered Intercellular Communication	Ocular cicatricial pemphigoid (OCP) is a chronic progressive disease characterised by exacerbations of immunologically driven conjunctival inflammation.	11965118
Communicable Diseases, Inflammation, Neoplasms	Altered Intercellular Communication	Biological signs of inflammation were present without any evidence of infection or neoplasm.	11965180
Tumor necrosis, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	Tumor necrosis factor-alpha (TNF-alpha) is a cytokine that is secreted from macrophages, and is related to a sequence of events in the response to inflammation and cancer formation.	11968052
Inflammation, Lung diseases	Altered Intercellular Communication	Arterial embolization to preoperatively manage pulmonary disease associated with inflammation.	11968721
Intraoperative Blood Salvage, Inflammation, Lung diseases	Altered Intercellular Communication	Preoperative arterial embolization is used in pulmonary disease to reduce intraoperative blood loss resulting from exposure of extensive adherent pleura due to repeated inflammation.	11968721
Inflammation, Carotid Arteries, Intracranial Aneurysm	Altered Intercellular Communication	These pathological findings indicated that there was old inflammation around the left extracranial carotid aneurysm, left carotid artery, and left cavernous sinus.	11968746
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Inflammation, resulting in periductal fibrosis and compression of the duct orifices, may be a causative factor.	11972224
Inflammation	Altered Intercellular Communication	Type Z-0 differed significantly from types Z-1, Z-2, and Z-3 with regard to the grade of inflammation, activity, and presence of H. pylori.	11972268
allergic inflammation	Altered Intercellular Communication	Different studies have described the eosinophil activation, evaluated by CD69 expression, at the site of an allergic inflammation.	11972480
Inflammation, Thrombosis	Altered Intercellular Communication	Secretory products of platelets serve important functions in inflammation and thrombosis.	11972716
Inflammation, Squamous cell carcinoma, Seminal Vesicles, Neoplasms	Altered Intercellular Communication	Squamous cell carcinoma arising from a seminal vesicular cyst: possible relationship between chronic inflammation and tumor development.	11972870
Squamous cell carcinoma, Chronic inflammation, Seminal Vesicles	Altered Intercellular Communication	Pathological examination revealed squamous cell carcinoma within a seminal vesicular cyst, along with squamous metaplastic foci and severe chronic inflammation.	11972870
Keratitis, Sensorineural Hearing Loss (disorder), Oculovestibuloauditory syndrome, Inflammatory abnormality of the eye	Altered Intercellular Communication	To lead ophthalmologists to consider Cogan syndrome when managing a patient presenting with keratitis or other ocular inflammation accompanied by sensorineural hearing loss.	11973382
Sensorineural Hearing Loss (disorder), Oculovestibuloauditory syndrome, Inflammatory abnormality of the eye, Scleritis, Uveitis, Retinal Vasculitis, Conjunctivitis	Altered Intercellular Communication	Four patients presented atypical Cogan syndrome (i.e., sensorineural hearing loss and chronic ocular inflammation such as uveitis, scleritis, conjunctivitis, retinal vasculitis, etc.).	11973382
Inflammation	Altered Intercellular Communication	No signs of acute or chronic inflammation could be found in patient 3.	11973390
Inflammation, Thickened	Altered Intercellular Communication	Pathologic findings were thickening and inflammation of the fascia and normal epidermis.	11974534
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Inflammation is thought to have a role in the pathogenesis of atherosclerotic coronary artery disease (CAD), and the measurement of markers of inflammation has been suggested to improve the identification of individuals at risk for this disease.	11975775
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a key role in the pathogenesis of atherosclerosis.	11975809
Acute inflammation	Altered Intercellular Communication	Preoperative and early postoperative inflammation was evaluated by quantifying the aqueous flare intensity with a laser flare photometer (Kowa FM-500).	11978455
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Accumulating evidence implicates inflammation as a potential pathway in the pathogenesis of type 2 diabetes.	11978661
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	They also add to the notion that low-grade inflammation is important in the pathogenesis of type 2 diabetes.	11978661
Inflammation	Altered Intercellular Communication	IL-8 seems to participate in the pathomechanism of nerve root inflammation in lumbar disc herniations, which implies that it may be considered a target for therapeutic intervention.	11979160
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The CNV was classified as "inflammatory active" (more inflammation than fibrosis) or "inflammatory inactive" (morefibrosis than inflammation).	11979237
Weight Gain, Inflammation	Altered Intercellular Communication	They increased in nine patients as nutritional status improved (albuminemia >30 g/l; transthyretinemia >200 mg/l or weight gain >5% of initial body weight) and levels of inflammation markers decreased (group 1).	11980621
Inflammation, Hypercatabolism	Altered Intercellular Communication	In patients with severe and persistent inflammation, high levels of proteolysis of IGFBP-3 may have contributed to the low plasma IGF-I levels, persistence of hypercatabolism and lack of improvement in nutritional status.	11980621
Adenomatous Polyposis Coli, CEL gene, Ulcerative Colitis	Altered Intercellular Communication	Eleven patients (group 1) with familial adenomatous polyposis (FAP) with no evidence of ileal pouch inflammation and 14 patients (group 2) with ileal pouch inflammation (all with a prior diagnosis of ulcerative colitis) underwent pouch endoscopy with biopsy.	11981337
Inflammation	Altered Intercellular Communication	The inflammatory process seen in ileal pouch inflammation is characterized by up-regulation of E-selectin and recruitment of CD15-positive cells, emphasizing the role of neutrophil recruitment and migration to the epithelium in the pathogenesis of this condition.	11981337
Inflammation	Altered Intercellular Communication	Peripheral blood markers of inflammation predict mortality and functional decline in high-functioning community-dwelling older persons.	11982663
Inflammation	Altered Intercellular Communication	In high-functioning older persons, a measure of inflammation can identify those at a much higher risk of mortality and a possibly higher risk of functional decline.	11982663
Communicable Diseases, Inflammation, Non-Functioning Endocrine Neoplasm	Altered Intercellular Communication	Occult infection of old nonfunctioning arteriovenous grafts: a novel cause of erythropoietin resistance and chronic inflammation in hemodialysis patients.	11982813
Inflammation	Altered Intercellular Communication	C-reactive protein (CRP) was measured as a marker of chronic inflammation.	11983200
atherosclerotic, Stroke, Lacunar	Altered Intercellular Communication	These findings suggest that lacunar stroke might result from genetic susceptibility to inflammation-mediated damage in concert with atherosclerotic risk factors.	11983287
Inflammation	Altered Intercellular Communication	A particular strain of H. pylori, the cytotoxin gene A strain (CagA strain), which has been associated with increased inflammation, has been reported to account for much of this relationship.	11984211
Tissue Adhesions, Obesity, Colitis	Altered Intercellular Communication	The essential causes of conversion were obesity, severe adhesions, and colonic inflammation.	11984674
Inflammation, Common Bile Duct Calculi	Altered Intercellular Communication	The groups were comparable with respect to the frequency of previous abdominal operations, acute inflammation of the gallbladder, and the frequency of bile duct calculi detected by intraoperative cholangiography.	11984675
Inflammation, Toxic effect	Altered Intercellular Communication	Symptoms of local toxicity were clinically similar to the signs of the initial viral inflammation.	11986086
Intraocular inflammation	Altered Intercellular Communication	Ocular involvement in these patients was associated with advanced age at onset (P < 0.001) and was characterized by severe intraocular inflammation.	11986090
Inflammation	Altered Intercellular Communication	It is possible that this results in increased thromboxane synthesis, which may in turn contribute to mucosal inflammation and intramucosal thrombogenesis.	11986343
Refractory Cytopenia of Childhood, Renal Cell Carcinoma	Altered Intercellular Communication	Epidemiological findings indicate that hormonal influences may play a role in the etiology of renal cell cancer (RCC).	11986775
Inflammation	Altered Intercellular Communication	The intra-articular findings of this study suggest that cartilage degradation and synovial inflammation are important components of chronic closed lock of the TMJ that respond well to arthroscopic lavage.	11988928
Inflammation, Primary malignant neoplasm, Neoplasms, Communicable Diseases, Cyst, Hepatitis B, Traumatic injury, Disease	Altered Intercellular Communication	Prevalence of hepatitis B and C virus (HBV, HCV) infection were compared between oral diseases such as inflammation, cysts, cancer, trauma, benign tumors, impacted teeth, or jaw deformity in dental inpatients (n = 5830) with adjustment for age, gender, and history of surgery.	11991310
Inflammation, Asthma	Altered Intercellular Communication	These data suggest that FP effectively controls inflammation in older patients, whereas Z may mask inflammation and may not provide the level of bronchodilatory or anti-inflammatory activity needed for effective asthma control in older patients.	11991558
Hepatic inflammation, immunoglobulin A, Alcohol-Induced Disorders	Altered Intercellular Communication	IgA against gut-derived endotoxins: does it contribute to suppression of hepatic inflammation in alcohol-induced liver disease?	11991606
Inflammation	Altered Intercellular Communication	The clinical course suggests that the inflammation extended from the left X cranial nerve ganglion.	11993191
Inflammation	Altered Intercellular Communication	Although debridement of the scrotum and inguinal region was immediately carried out, the inflammation extended to the right abdominal region 2 days later.	11993211
Italy	Altered Intercellular Communication	[Floating-Harbor syndrome: first case in Italy associated with growth hormone deficiency].	11995206
Colitis	Altered Intercellular Communication	In this article we describe eight cases of colonic inflammation associated with nonsteroidal antiinflammatory drug administration; our aim is to stress the importance of an underestimated entity by clinicians.	11995447
Inflammation	Altered Intercellular Communication	In all these subjects a careful drug history has been taken in a prospective manner and colonic inflammation appeared to be directly related to NSAID administration.	11995447
Uterine Tachysystole, Neoplasms, Endocrine System Diseases, adrenal dysfunction, Histogenic Process	Altered Intercellular Communication	The histogenesis of adrenal ML is not clear and this lesion has been found to be associated with endocrine disorders, other adrenal dysfunction and tumors, and hyperstimulation with adrenocorticotropic hormone.	11996801
Inflammation, Ulcer	Altered Intercellular Communication	Innumerable small and deep ulcers were also observed, consisting of nonspecific inflammation.	11998948
Inflammation, Dental Plaque, Epithelial Attachment	Altered Intercellular Communication	The periodontal status was assessed by clinical measurement of levels of bacterial plaque (PLI), gingival inflammation (GI) and loss of epithelial attachment (LA).	12000352
Inflammation, Squamous cell carcinoma, Keratosis	Altered Intercellular Communication	Inflammation is associated with progression of actinic keratoses to squamous cell carcinomas in humans.	12000377
Inflammation, Acne, Propionibacterium	Altered Intercellular Communication	Cutaneous propionibacteria are implicated in acne pathogenesis, although their exact role in the genesis of inflammation is still poorly understood.	12000382
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Cerebrovascular transforming growth factor-beta contributes to inflammation in the Alzheimer's disease brain.	12000710
vascular inflammations, Coronary heart disease	Altered Intercellular Communication	Increased levels of markers of vascular inflammation in patients with coronary heart disease.	12002414
Celiac Disease, Mucous Membrane, Gastrointestinal inflammation	Altered Intercellular Communication	Celiac disease (CD) is characterized by small intestinal inflammation and mucosal atrophy.	12003429
Delirium, Toxic effect, Dementia	Altered Intercellular Communication	Anticholinergic toxicity is especially problematic in delirious, demented patients, because most dementias are associated with pre-existing deficiencies in cholinergic neurotransmission.	12003684
Inflammation, Blood Coagulation Disorders	Altered Intercellular Communication	This arouses doubts as to whether protein C-protein S complex is effective in inhibition of inflammation and limitation of coagulopathy.	12004145
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	Secondary damage after central nervous system (CNS) injury is driven in part by oxidative stress and CNS inflammation and is substantially mediated by cyclooxygenases (COXs).	12005397
Infection, Neutrophilic Eccrine Hidradenitis	Altered Intercellular Communication	Neutrophilic eccrine hidradenitis (NEH) is a self-restricted inflammatory condition, usually secondary to chemotherapeutic agents and less frequently to other drugs such as zidovudine or various infections.	12006137
Communicable Diseases, Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	To measure the clinical usefulness of quantitative CD64 measurements to differentiate between systemic infection and active autoimmune inflammation in an ongoing study.	12006325
Inflammation, Hypertensive (finding), Atherosclerosis	Altered Intercellular Communication	Although positive effects were also observed in those who were hypertensive and smoking at the time of CRP measurement, findings suggest that in clinically healthy men, atherosclerosis could have origins more closely linked with inflammation than with other processes.	12007546
Inflammation, Hemorrhage	Altered Intercellular Communication	Extensive hemorrhage involving the endotracheal pulmonary field and lymphocyte infiltration of the alveolar space likely appeared after the inflammation.	12009078
Hematemesis	Altered Intercellular Communication	An exaggerated hematemesis that occurred immediately after hospital admission indicated an inflammatory condition of the digestive tract that was caused by buckwheat.	12009078
Inflammation, Gray Platelet Syndrome	Altered Intercellular Communication	Furthermore, the possibility that pallid pulmonary pathology may result from persistent inflammation due to microhemorrhage owing to the platelet defect was examined.	12009785
Inflammatory abnormality of the eye, Fever, CTCAE, Blood Circulation	Altered Intercellular Communication	A Gram-positive coccobacillus was isolated from the bloodstream, he was treated with fluoroquinolone with disappearance of fever, decreased ocular inflammation, and improvement in his vision to light perception.	12010601
Cholesteatoma, Inflammation	Altered Intercellular Communication	Cholesteatomas were collected from 16 patients operated on for chronic inflammation of the middle ear.	12011767
Inflammation, Fever, CTCAE, Heart failure, Nausea, Myalgia, CTCAE 5	Altered Intercellular Communication	The patient, who was in a stable clinical condition with low signs of inflammation at that time, deteriorated 3 days after the first dose of 200 mg infliximab with fever, nausea, myalgia and signs of cardiac failure.	12012225
physiopathological	Altered Intercellular Communication	No relationship between parental sexual behavior and maternal hormonal dysfunction was found.	12012598
Inflammation, Atherosclerosis	Altered Intercellular Communication	In the later case there are strong interactions between atherosclerotic cardiovascular disease, inflammation and nutritional parameters.	12012752
Granulomatous inflammation, Hyperplasia, Necrosis	Altered Intercellular Communication	Endometrial curettings performed on a 63-year-old woman with a bloody vaginal discharge and thickened endometrium disclosed complex atypical hyperplasia and granulomatous inflammation with caseation necrosis.	12012885
Endometrial adenocarcinoma, Necrosis	Altered Intercellular Communication	The uterus contained a well-differentiated endometrial adenocarcinoma with squamous differentiation invading about one-half the myometrial thickness and granulomatous inflammation with caseation necrosis.	12012885
Inflammation, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	Eosinophilic inflammation of the airway is usually associated with airway hyper-responsiveness in bronchial asthma.	12014210
Inflammation, Respiratory Hypersensitivity, Bronchitis	Altered Intercellular Communication	However, there is a small group of patients which has the eosinophilic inflammation in the bronchial tree with normal spirometry and no evidence of airway hyper-responsiveness, which was named eosinophilic bronchitis.	12014210
Airway structure, Chronic cough	Altered Intercellular Communication	Assessment of airway inflammation by sputum examination is important in investigating the cause of chronic cough.	12014210
Eosinophilic disorder, Inflammation, Epithelial	Altered Intercellular Communication	Intraepithelial inflammation, epithelial loss or detachment, inflammation in the lamina propria, presence of eosinophilia, crypt inflammation, Paneth's cell metaplasia, and collagen layer thickness were recorded.	12014722
Inflammation	Altered Intercellular Communication	Among the histological parameters only the degree of inflammation in the lamina propria significantly differed between the three response groups (p = 0.007).	12014722
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by a neutrophilic airway inflammation that can be demonstrated by examination of induced sputum.	12016098
ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	Smokers who develop chronic obstructive pulmonary disease (COPD) have a chronic bronchopulmonary inflammation that is characterized by an increased infiltration of T-lymphocytes, particularly CD8(+), in the airways and lung parenchyma.	12016104
Gingivitis, Dental Plaque	Altered Intercellular Communication	Both dentifrices resulted in statistically significant reductions in dental plaque, gingival inflammation, and stain at all time periods compared to baseline.	12017933
Cystitis, Eosinophilic inflammation	Altered Intercellular Communication	Historically, eosinophilic cystitis is a rare disorder of bladder inflammation with eosinophils infiltration diagnosed by pathologic examination.	12017980
Inflammation, Malnutrition	Altered Intercellular Communication	Inflammation and malnutrition as predictors of mortality in patients on hemodialysis.	12018629
Inflammation, Malnutrition, Hypoalbuminemia	Altered Intercellular Communication	Although, classically, hypoalbuminemia has been attributed to malnutrition, inflammation can also predict the serum albumin concentration in dialysis patients.	12018629
HD Term Type, Inflammation	Altered Intercellular Communication	To establish the influence of nutritional status and inflammation on mortality in HD patients.	12018629
Malnutrition, HD Term Type, Inflammation	Altered Intercellular Communication	Inflammation, as measured by CRP, and malnutrition, as measured by IGF-1 levels, are associated with mid-term mortality in HD patients.	12018629
Inflammation, Hypertension, CTCAE, Microcirculatory Bed, Diabetes Mellitus	Altered Intercellular Communication	To examine the relation of retinal arteriolar narrowing, a marker of microvascular damage from aging, hypertension, and inflammation, to incident diabetes in healthy middle-aged persons.	12020333
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Aortic inflammation and the genes that regulate the immune response play an important role in abdominal aortic aneurysm pathogenesis.	12021716
Inflammation	Altered Intercellular Communication	However, the modulating effects of such genetic and other environmental factors on the severity on aneurysm inflammation is not known.	12021716
Aneurysm, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Aneurysm specimens were obtained at the time of operation from 96 consecutive patients who underwent abdominal aortic aneurysm repair and were graded for degree of histologic inflammation.	12021716
Inflammation, Aneurysm	Altered Intercellular Communication	Multivariate analysis was used to determine the association of genetic and environmental factors with degree of inflammation and to determine the HLA-associated disease risk for aneurysm.	12021716
Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Active cigarette smoking and female gender are significant disease-modulating factors associated with increased abdominal aortic aneurysm inflammation.	12021716
Retinal Edema, vascular inflammations	Altered Intercellular Communication	Small, hard exudates were present in the posterior pole during absorption of the retinal edema and resolution of the vascular inflammation.	12022285
Refractory anemias, Rheumatoid Arthritis, Inflammation, Atherosclerosis	Altered Intercellular Communication	To measure markers of atherogenesis and thrombogenesis in patients with rheumatoid arthritis (RA) and in matched controls, and to relate these variables to markers of inflammation and endothelial activation, and to the presence of atherosclerosis.	12022343
Pancreatitis	Altered Intercellular Communication	Ultrasonography revealed inflammatory changes of the pancreas in 40 of 51 patients evaluated, while computed tomogram demonstrated evidence of pancreatic inflammation for all 21 patients evaluated.	12022736
Inflammation, Hyperplasia	Altered Intercellular Communication	All samples presented with hyperplasia of the epidermis associated with local inflammation.	12023143
Inflammation, Idiopathic achalasia of esophagus	Altered Intercellular Communication	Tissue obtained at the time of esophagomyotomy revealed lymphocytic myenteric inflammation and marked depletion of ganglion cells identical to that seen in primary achalasia.	12023584
Inflammatory abnormality of the eye, Vitreous inflammatory cells	Altered Intercellular Communication	We selected five patients who had ocular inflammation which presented on the ocular fundus examination typical multifocal yellow-white patches of depigmentation of choroid and pigment epithelium and vitreous inflammation.	12023743
Inflammation, Helicobacter pylori	Altered Intercellular Communication	Adherence of Helicobacter pylori to gastric epithelial cells and mucosal inflammation.	12024112
Inflammation, Helicobacter pylori	Altered Intercellular Communication	Adherence of Helicobacter pylori to the gastric epithelium is believed to be an important step in the induction of active inflammation of the mucosal layer.	12024112
Inflammatory disease of mucous membrane	Altered Intercellular Communication	However, structural evidence showing a quantitative relationship between the adherence of H. pylori and severity of gastric mucosal inflammation is lacking.	12024112
Gastritis	Altered Intercellular Communication	A quantitative correlation was found between adherence of H. pylori and gastric inflammation.	12024112
Inflammation	Altered Intercellular Communication	Both adherence and the induction of inflammation were found to be related to the structure of H. pylori.	12024112
Papilledema	Altered Intercellular Communication	By univariate analysis, a clinically acute inflammatory condition and elevation of serum transaminase levels were significantly associated with moderate and severe endoscopic papillitis (p < 0.05).	12024144
Papilledema	Altered Intercellular Communication	However, by multivariate analysis, only a clinically acute inflammatory condition was significantly associated with moderate and severe endoscopic papillitis (p < 0.001).	12024144
Pancreatic Diseases, Papilledema	Altered Intercellular Communication	Moderate and severe endoscopic papillitis were significantly more common in patients with biliary or pancreatic disorders plus a clinically acute inflammatory condition, whereas moderate and severe papillitis were not observed in healthy volunteers.	12024144
Urethritis, Urethra	Altered Intercellular Communication	The etiology include 14 patients after perineal urethral trauma, in 10 patients the main cause was urethral inflammation of posterior urethra, in 8--as a consequence of transurethral surgery and in 5--after suprapubic prostatectomy.	12024672
Hormone abnormality, Hypersensitivity, Candidiasis, Chronic Mucocutaneous, Burn injury	Altered Intercellular Communication	The differential diagnoses may range from chemical and electrical burns to conditions such as allergic reactions, hormonal disorders, and mucocutaneous conditions.	12024748
Communicable Diseases, Inflammation, Atrophic, Leprosy	Altered Intercellular Communication	Infection by H. pylori, inflammation and atrophy were found to be significantly more in leprosy patients as compared to controls (p < 0.01, < 0.005 and < 0.02 respectively).	12024911
Inflammation, Leprosy	Altered Intercellular Communication	On comparing the histopathological changes in various subgroups of leprosy, H. pylori, inflammation and activity showed a statistically decreasing trend from tuberculoid to lepromatous subgroups (p < 0.05, < 0.001, < 0.01 respectively).	12024911
Inflammation, Thrombosis, Atherosclerosis	Altered Intercellular Communication	Inflammation and thrombosis may play a role at early stages of atherosclerosis.	12025898
Inflammation, Thrombosis, atherosclerotic	Altered Intercellular Communication	Thus, (1) FMD was reduced at early stages of CAD while IMT was increased in advanced CAD, and (2) inflammation and thrombosis may play a role in the early stages of the atherosclerotic process.	12025898
Inflammation, Coronary Stenosis	Altered Intercellular Communication	The present data suggested that inflammation may play an important role in the pathogenesis of UA, and the plasma levels of CRP might have a higher prognostic value than the severity of coronary stenosis correlated with the clinical outcome of instability despite of lipid profile status.	12025913
Inflammation	Altered Intercellular Communication	Evidence for the role of chronic inflammation in atherogenesis has been well documented.	12026533
Inflammation, Rhinosinusitis, Nasal Polyps	Altered Intercellular Communication	We aimed to assess the presence of apoptotic cells in nasal polyps from aspirin-hypersensitive (AH) and aspirin-tolerant (AT) patients with rhinosinusitis as related to the characteristics of local inflammation.	12028114
Inflammation, Nasal Polyps	Altered Intercellular Communication	We conclude, that decreased apoptosis of inflammatory cells in nasal polyps from ASA-hypersensitive patients, reflects a distinct mechanisms of local inflammation and may be related to persistence and severity of the disease in these patients.	12028114
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	Within the range of albumin levels in these patients, nutritional variables primarily affected albumin synthesis while inflammation caused hypoalbuminemia by increasing albumin FCR.	12028466
Inflammation	Altered Intercellular Communication	Chalazions are a common occurrence in the eyelids due to chronic inflammation in the tarsal plate.	12029575
Inflammation, Arthritis, leukemia, Leukemic Infiltration	Altered Intercellular Communication	Proposed pathogenic mechanisms of arthritis in leukemia are leukemic infiltration of synovial tissue and resulting periosteal and capsular inflammation.	12029594
Inflammation	Altered Intercellular Communication	It is also important to actively treat this condition surgically, including ligation of internal jugular vein for suppressing inflammation.	12030441
Deficit, Hypermetabolism	Altered Intercellular Communication	These data underline the importance of correcting the multiple hormonal deficits in patients with prolonged critical illness to counteract the hypercatabolic state.	12030918
Inflammation, Stenosis, Ulcer	Altered Intercellular Communication	Although longitudinal ulcers or scars, stricture, and a cobble-stone appearance were not observed, transmural inflammation and deep fissures were found in the interpolypoid area.	12031089
Inflammation, Mesothelial hyperplasia, Hepatitis	Altered Intercellular Communication	The histopathology diagnosis of liver biopsy was erythrostasis and non-specific hepatitis and for peritoneal tubercle was non-specific chronic inflammation with mesothelial hyperplasia.	12032447
Inflammation, Infectious disorder of bronchus	Altered Intercellular Communication	REE and TEE were not correlated with bronchial infection or inflammation.	12032517
Inflammation, Weight decreased, Obesity	Altered Intercellular Communication	Markers of chronic inflammation and obesity: a prospective study on the reversibility of this association in middle-aged women undergoing weight loss by surgical intervention.	12032750
Inflammation, Obesity	Altered Intercellular Communication	Human adipose tissue expresses and releases proinflammatory cytokines and these measures of chronic inflammation have recently been associated with obesity.	12032750
Chagas Disease, Bradycardia, Tachycardia by ECG Finding, Depression, CTCAE	Altered Intercellular Communication	Chagas' disease subjects without overt manifestations presented variable and subtle depression and less frequent enhancement or normality of the rate- and time-dependent tachycardia and bradycardia reflex responses related to Valsalva manoeuvre, which demonstrates distinct patterns of finely disturbed cardiac sinus parasympathetic and sympathetic modulation, probably due to inflammatory or autoimmunological damage of intrinsic innervation and/or to autoantibodies-induced derangement in neurotransmitter receptors.	12036188
Inflammation, Macular Edema, Cystoid	Altered Intercellular Communication	There were no cases of IOL-related inflammation or a clinically significant cystoid macular edema.	12036642
Inflammation, Hypertriglyceridemia	Altered Intercellular Communication	Hypertriglyceridemia may be related to chronic low-grade inflammation or to a dietary macronutrient imbalance with excessive simple carbohydrate absorption relative to fat absorption.	12036806
Airway structure, Atopy	Altered Intercellular Communication	Exhaled nitric oxide (eNO), which has been proposed as a measure of airway inflammation, is increased in atopic subjects.	12037227
Airway structure, Asthma, MS4A2 wt Allele	Altered Intercellular Communication	This raises the question of whether eNO provides any additional information about airway inflammation in asthmatic subjects, other than as a marker for atopy.	12037227
Inflammation, Coronary heart disease	Altered Intercellular Communication	Because coronary heart disease is increasingly seen as an inflammatory process, it might be reasonable to hypothesize that physical activity reduces risk of coronary heart disease by reducing or preventing inflammation.	12038947
Nasal inflammation	Altered Intercellular Communication	Ambient exposure and nasal inflammation in adults and children--a preliminary analysis.	12040920
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	Future analysis will concentrate on temporal relations between inflammation and exposure, including individual risk factors such as allergy, smoking and the presence of disease.	12040920
Inflammation	Altered Intercellular Communication	The TSCT and MRI findings correlated well with the pathological results, corresponding to fibrous thickening of the alveolar septa with mild chronic inflammation.	12041705
physiopathological	Altered Intercellular Communication	Therefore hormonal dysfunction can also have contributed to the blepharokeratoconjunctivitis in this patient.	12043294
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	To determine the yield of diagnostic pars plana vitrectomy in eyes with suspected posterior segment inflammation or malignancy when clinical examination and systemic laboratory testing did not yield a specific diagnosis.	12045054
Inflammation, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	Considering that atherosclerosis is inflammation of the vascular wall, simvastatin may have a beneficial effect on cardiovascular disease, in part because it alleviates inflammation.	12046033
Inflammation, Pneumonia	Altered Intercellular Communication	Seihai-to might not improve the swallowing reflex, but might instead improve a defense mechanism or excessive inflammation caused by pneumonia in the lower airway.	12046858
Inflammation, Hypertension, CTCAE, diabetic	Altered Intercellular Communication	This study examined the associations between vascular function and markers of inflammation in Type 2 diabetic subjects with treated hypertension.	12048137
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	These cross-sectional observations are consistent with the hypothesis that reduced FMD and GTNMD in Type 2 diabetes is at least in part secondary to increased inflammation, with associated endothelial and platelet activation.	12048137
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Alternatively, DR2 has a direct role in restricting immunological responses to the low-grade inflammation characteristic of OA.	12048293
Corneal decompensation, Inflammation	Altered Intercellular Communication	In both cases, a significant inflammation of the anterior chamber and corneal decompensation were noted before vitrectomy.	12048515
Inflammation, Decompression of nerve	Altered Intercellular Communication	Magnetic resonance imaging(MRI) findings showed compression of the optic nerve at the orbital apex by marked thickening of the right lateral rectus muscle and superior rectus muscle, and inflammation directly invading the optic nerve.	12048927
Inflammation, Calcinosis	Altered Intercellular Communication	After admission to our hospital, kidney, ureter, bladder X-ray, computed togography and cystoscopy revealed calcification of about two-thirds of the mucosa of the bladder, and biopsy of the bladder revealed bacterial colonies with inflammation and calcification.	12048934
Inflammation, Calcinosis	Altered Intercellular Communication	After treatment with antibiotics and irrigation with solita T1, an acidic solution of pH 3.5-6.5, inflammation and calcification were significantly reduced.	12048934
Inflammation, Infectious Otitis Media, Master of Electrical Engineering, Acute otitis media, Otitis Media with Effusion	Altered Intercellular Communication	Our primary objective was to assess diagnostic accuracy for acute otitis media (AOM) relative to the criterion standard established by the United States Agency for Healthcare Research and Quality: middle-ear effusion (MEE) plus onset in the past 48 h of signs or symptoms of middle-ear inflammation.	12049821
Inflammation, Leukocytosis, Neoplasms	Altered Intercellular Communication	Laboratory findings revealed leukocytosis and C-reactive protein elevation, compatible with inflammation of the tumor.	12051538
Low Vision, Inflammation, Unspecified visual loss	Altered Intercellular Communication	A 42-year-old man presented with bilateral decreased vision, transient visual loss, and anterior segment inflammation.	12052411
allergic inflammation	Altered Intercellular Communication	The nasal epithelium is considered to play and active role in the allergic inflammation through its capacity to synthesize and release a wide range of cytokines and mediators.	12053657
Sheehan Syndrome, Chronic Kidney Diseases	Altered Intercellular Communication	Continuous subcutaneous infusion of recombinant human growth hormone (rhGH) improved renal function in a patient with Sheehan's syndrome associated with chronic renal failure.	12054116
Inflammation, Infancy, Cortical Congenital Hyperostosis, Osteomyelitis, Hyperostosis	Altered Intercellular Communication	Infectious causes (abscess, parotid inflammation and osteomyelitis) must be evoked and distinguished from infantile cortical hyperostosis (Caffey-Silverman's syndrome).	12055539
Inflammation	Altered Intercellular Communication	The interstinoscopy showed blister-like lesions and signs of inflammation only in the proximal part of the oesophagus.	12055666
Iron-Refractory Iron Deficiency Anemia, Inflammation	Altered Intercellular Communication	Laboratory studies revealed microcytic anemia and elevated levels of inflammation markers.	12056296
Plaque, Atherosclerotic	Altered Intercellular Communication	Imaging atherosclerotic plaque inflammation with [18F]-fluorodeoxyglucose positron emission tomography.	12057982
Inflammation	Altered Intercellular Communication	Current imaging techniques provide anatomic data but no indication of plaque inflammation.	12057982
Inflammation, atherosclerotic	Altered Intercellular Communication	In this study we tested whether 18FDG-PET imaging can identify inflammation within carotid artery atherosclerotic plaques.	12057982
Plaque, Atherosclerotic	Altered Intercellular Communication	This study demonstrates that atherosclerotic plaque inflammation can be imaged with 18FDG-PET, and that symptomatic, unstable plaques accumulate more 18FDG than asymptomatic lesions.	12057982
Ocular sarcoidosis, Inflammatory abnormality of the eye	Altered Intercellular Communication	An adequate control of ocular inflammation may improve the prognosis in patients with ocular sarcoidosis.	12058287
Intestinal metaplasia, Inflammation, Helicobacter pylori, Atrophic	Altered Intercellular Communication	We searched for differences in occurrence of Helicobacter pylori, inflammation, atrophy, intestinal metaplasia and dysplastic changes.	12059060
Intestinal metaplasia, Inflammation, polyps, Atrophic	Altered Intercellular Communication	There were no differences in the occurrence of polyps, H. pylori, inflammation, activity, atrophy nor intestinal metaplasia tested with binaric, logistic, regression analysis.	12059060
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	This case suggests that autologous stem cell transplantation can change not only the clinical course, but also the natural history of intestinal inflammation in Crohn disease.	12059066
Inflammation, Data types - Address	Altered Intercellular Communication	Since in a previous work E3/E3 were found to be associated with the highest plasma levels of alpha1-antichymotrypsin, another acute-phase protein, the present findings seem to support the hypothesis that inflammation may be a relevant factor in AD pathogenesis peculiar to E3/E3 subjects.	12059070
Granuloma Annulare	Altered Intercellular Communication	T-cell receptor repertoire and cytokine pattern in granuloma annulare: defining a particular type of cutaneous granulomatous inflammation.	12060389
Communicable Diseases, Meningitis	Altered Intercellular Communication	The diagnostic accuracy of these signs was not significantly better in the subsets of patients with moderate meningeal inflammation (>/=100 WBCs/mL of CSF) or microbiological evidence of CSF infection.	12060874
Nuchal Rigidity, Meningitis	Altered Intercellular Communication	Only for 4 patients with severe meningeal inflammation (>/=1000 WBCs/mL of CSF) did nuchal rigidity show diagnostic value (sensitivity, 100%; negative predictive value, 100%).	12060874
Inflammation, Asthma	Altered Intercellular Communication	T cells expressing the gammadelta receptor are essential for Th2-mediated inflammation in patients with acute exacerbation of asthma.	12061423
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Inflammation may play a pathogenic role in chronic heart failure (CHF).	12062373
Inflammation, diabetic, Thrombophilia, Ischemia	Altered Intercellular Communication	Markers of inflammation and hypercoagulability in diabetic and nondiabetic patients with lower extremity ischemia.	12062538
Lower limb ischemia, Inflammation, Thrombophilia, Atherosclerosis	Altered Intercellular Communication	Lower extremity ischemia is one aspect of atherosclerosis, a disease associated with both inflammation and hypercoagulability.	12062538
Inflammation, Blood Clot	Altered Intercellular Communication	Many recent studies have focused on a diversity of mechanisms by which inflammation can promote blood clotting.	12062538
Inflammation, Blood Clot	Altered Intercellular Communication	However, it has not been proven that inflammation can actually trigger clinically relevant thrombus formation in vivo.	12062538
Inflammation, Thrombophilia, Diabetes Mellitus	Altered Intercellular Communication	The purpose of the study was to determine the plasma levels of markers of inflammation and their possible association with markers for coagulability with special emphasis on the difference between patients with and without diabetes.	12062538
Ischemia, Inflammation, diabetic	Altered Intercellular Communication	It is concluded that there is a difference between diabetic and nondiabetic patients with lower limb ischemia with the former showing stronger signs of inflammation.	12062538
Inflammation	Altered Intercellular Communication	During the 6 months of follow-up, there was no recurrence or any postoperative complication, such as graft rejection, symblepharon, or chronic inflammation.	12063048
Inflammation, Cholangiocarcinoma	Altered Intercellular Communication	As the biliary CA 125 was less affected by inflammation and hepatolithiasis, it is more useful than CEA and CA 19-9 in the diagnosis of cholangiocarcinoma.	12063953
Pancreatitis	Altered Intercellular Communication	Acute pancreatitis may be accompanied by alterations of the secretion of pancreatic and gastrointestinal peptides as a result of pancreatic inflammation.	12063974
Inflammatory abnormality of the eye	Altered Intercellular Communication	None of the patients had any signs of ocular surface inflammation as detected by slit-lamp examination, a normal Schirmer's test and tear breakup time.	12065853
Inflammation, Thrombophilia	Altered Intercellular Communication	Parallel to acute inflammation of pancrease a hypercoagulation syndrome developed.	12066554
Inflammation, Alveolar Bone Loss	Altered Intercellular Communication	A 10-year-old boy presented with generalized gingival inflammation, extensive alveolar bone loss, and tooth mobility.	12066651
Inflammation	Altered Intercellular Communication	Cytokines regulate inflammation associated with cardiopulmonary bypass (CPB).	12066724
Inflammation, Anti-Glomerular Basement Membrane Disease	Altered Intercellular Communication	Goodpasture's disease is characterized by the binding of IgG autoantibodies to the glomerular basement membrane, leading to glomerular inflammation.	12067312
Amyotrophic Lateral Sclerosis, Nerve Degeneration	Altered Intercellular Communication	There is evidence that an imbalance between glutamatergic and inhibitory neurotransmission may contribute to selective neurodegeneration in amyotrophic lateral sclerosis (ALS).	12067327
Helicobacter pylori, Gastritis, Malignant neoplasm of stomach, Neoplasms, Adenocarcinoma, Non-Malignant	Altered Intercellular Communication	Considering the high prevalence of stomach cancer in the northern region of Brazil and the recognized relationship between chronic gastric inflammation caused by Helicobacter pylori, and its carcinogenic potential, the objective we had with this study was to investigate the presence of the microorganism in macro and microscopic presentations of neoplasm in different regions of the stomach, and in non-malignant lesions concomitant to the adenocarcinoma in patients originating from the metropolitan area of Belem (State of Para, Brazil).	12068534
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Elevated serum concentrations of YKL40 are found in patients with diseases characterized by inflammation or ongoing fibrosis.	12069012
Organ Dysfunction Scores	Altered Intercellular Communication	Increased hepatosplanchnic inflammation precedes the development of organ dysfunction after elective high-risk surgery.	12069179
Inflammation	Altered Intercellular Communication	These results suggest that the T cells are being actively recruited to the site of inflammation along the chemokine gradients but are not participating in a classical immune response.	12069343
Inflammation	Altered Intercellular Communication	An increased C-reactive protein level is a powerful independent prognostic indicator for subsequent cardiac events, suggesting that late clinical outcome is markedly influenced by pre-procedural systemic activation of inflammation.	12069451
Chronic heart failure	Altered Intercellular Communication	In chronic heart failure, several hormonal systems are activated with diagnostic and prognostic implications.	12069452
Inflammation, Alpha one fetoprotein measurement, Pyelonephritis	Altered Intercellular Communication	Acute focal pyelonephritis (AFP) is a variant of pyelonephritis in which single or multiple discrete areas show changes of inflammation.	12069464
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The effects of inhaled fluticasone on airway inflammation in chronic obstructive pulmonary disease: a double-blind, placebo-controlled biopsy study.	12070058
Airway structure, ARCN1 gene, Exacerbation	Altered Intercellular Communication	Symptoms significantly improved, and there were significantly fewer exacerbations in subjects on FP, compared to subjects on P. The data indicate that inhaled fluticasone does affect selected aspects of airway inflammation in COPD, and this may explain, in part, the decrease in exacerbations seen in long-term studies with fluticasone propionate.	12070058
Inflammation, Hyperplasia	Altered Intercellular Communication	The inflammation is always present in these cysts and may have an important role in their pathogenesis because it stimulates hyperplasia and cystic change of the reduced enamel epithelium or the epithelial cell rests of Malassez.	12070473
Arteritis	Altered Intercellular Communication	Leukotriene A(4)-hydrolase expression and leukotriene B(4) levels in chronic inflammation of bacterial origin: immunohistochemistry and reverse-phase high-performance liquid chromatography analysis of oral mucosal epithelium.	12070603
Inflammation	Altered Intercellular Communication	Chronic inflammation of the oral epithelium of bacterial origin is associated with elevated leukotriene B(4) (LTB(4)) levels.	12070603
Inflammation	Altered Intercellular Communication	Epithelial cells may participate in early stages of inflammation as a source of LTB(4).	12070603
Acute sinusitis	Altered Intercellular Communication	Supposition and verification of chance of fungal origin is essential in cases of chronic inflammation of paranasal sinus and/or their complications for complex recovery.	12073542
Inflammation, Peritonitis, Specimen Source Codes - Abscess	Altered Intercellular Communication	If peritoneal dialysis is being performed and inflammation reactions continue, it is necessary to examine the patient for perforated peritonitis and abscess formation.	12073595
Asthma, Bronchitis	Altered Intercellular Communication	While the bronchial cytology of these two types of asthma is comparable, the immunological mechanisms of intrinsic asthma remain poorly understood because the factors responsible for the bronchial inflammation are unknown.	12073795
Inflammation, Compression, Budd-Chiari Syndrome, Pseudoaneurysm	Altered Intercellular Communication	Because of the venous outflow obstruction involved in femoral pseudoaneurysms with secondary venous compression and the surgical difficulty caused by surrounding inflammation, avoidance of thrombin injection in favor of early surgical intervention is suggested.	12075599
Inflammation, Periodontitis	Altered Intercellular Communication	As the fimbrial adhesins of putative periodontal pathogens are able in vitro to induce inflammation and bone resorption via stimulation of the proinflammatory cytokine production, the demonstrated fimbrial adhesins suggest the significant role of bacterial adhesion to sulcular epithelium in periodontitis.	12076819
Fibrosis Assessment, Necrosis with inflammation	Altered Intercellular Communication	The grade of necro-inflammation as well as the stage of fibrosis significantly correlated with the HNE index.	12076862
Fatty Liver, Inflammation, Fatty Liver Disease	Altered Intercellular Communication	Regarding 8-OHdG, although no 8-OHdG expression was observed in normal liver and only a few in fatty liver, 11 of 17 cases (64.7%) with NASH exhibited nuclear expression of 8-OHdG in hepatocytes and sinusoidal cells in areas of active inflammation.	12076862
Necrosis with inflammation	Altered Intercellular Communication	The 8-OHdG index significantly correlated with the grade of necro-inflammation.	12076862
Inflammation, Fatty infiltration	Altered Intercellular Communication	There was no correlation between the MRS-detectable abnormalities and the degree of inflammation or fatty infiltration of the muscle, as measured by MRI.	12077012
Inflammation, Cholelithiasis, Nephrolithiasis	Altered Intercellular Communication	High urine concentration of phospholipid (acyl derivatives) degradation products and cholesterol in patients with combination of nephrolithiasis with cholelithiasis changes solubilizing and micello-forming ability of urine and can directly stimulate crystal formation and development of aseptic inflammation in renal parenchyma.	12077822
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The multi-faceted components of the metabolic syndrome now include markers of inflammation and endothelial activation.	12080455
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome variables, cytokines (IL6 and TNFalpha), markers of inflammation and endothelial activation were measured in 107 Caucasian non-diabetic subjects aged 40-75 y.	12080455
Inflammation, Hyperinsulinism, Dyslipidemias	Altered Intercellular Communication	Men were centrally more obese and had increased markers of endothelial activation, inflammation and the anti-fibrinolytic state as well as hyperinsulinaemia and dyslipidaemia, compared with women.	12080455
vascular inflammations, Restenosis	Altered Intercellular Communication	Vascular inflammation and disturbed coagulation are suggested to cause restenosis after percutaneous transluminal angioplasty (PTA).	12083502
Inflammatory disease of mucous membrane	Altered Intercellular Communication	The cag pathogenicity island (PAI) status, as determined by cagE polymerase chain reaction, but not the status of iceA or HP0441, is closely associated with NF-kappaBeta activation and the degree of gastric mucosal inflammation in the hosts.	12084029
Inflammation, Angina, Unstable, Myocardial Infarction	Altered Intercellular Communication	Systemic inflammation in unstable angina is the result of myocardial necrosis.	12084588
Inflammation	Altered Intercellular Communication	With the appendix showing no macroscopic signs of inflammation, laparoscopy was continued and a perforated MD was identified 50 cm proximal to the ileocecal valve.	12085134
Inflammation, Musculoskeletal Pain	Altered Intercellular Communication	Marimastat treatment was associated with the development of musculoskeletal pain and inflammation.	12085177
Inflammation, Fibrosis Assessment, Fatty degeneration, Fatty Liver Disease	Altered Intercellular Communication	Although there was a trend toward higher serum ferritin levels among C282Y heterozygotes with NASH, there were no differences in histologic grades of steatosis, inflammation, or fibrosis between individuals with and without C282Y.	12085358
Fibrosis Assessment, Hepatitis, Diabetes Mellitus	Altered Intercellular Communication	Multivariate analysis identified female sex, diabetes mellitus, and more severe liver inflammation but not HFE mutations, serum ferritin, iron saturation, or hepatic iron staining as independent predictors of hepatic fibrosis.	12085358
Dental Plaque, Plaque, Atherosclerotic	Altered Intercellular Communication	In order to evaluate their possible contribution to atherosclerotic plaque inflammation, we measured their relative levels in postmortem plaque and adjacent normal arterial tissue.	12086701
Inflammation, atherosclerotic	Altered Intercellular Communication	COX-2 levels are sharply upregulated in atherosclerotic plaques, indicating that it may be a significant contributor to plaque inflammation.	12086701
Inflammation	Altered Intercellular Communication	Accordingly, COX-2 inhibitors may reduce the degree of inflammation and protect against future cardiovascular events.	12086701
Refractory anemias, Inflammation	Altered Intercellular Communication	In an in vivo study, 32 patients with RA (with prior CS therapy/without SSI: n=7; without prior CS therapy/with SSI: 6; with prior CS therapy/with SSI: 19) were investigated for synovial inflammation.	12087060
Inflammation	Altered Intercellular Communication	These results underscore that coupling of an efficient secretion of systemic cortisol together with local production of NE is important in order to lower synovial inflammation.	12087060
Dupuytren Contracture	Altered Intercellular Communication	The speculation is that alterations in gap junction intercellular communication may be involved in the progression of Dupuytren's nodules to cords as the disease progresses.	12087251
Inflammation	Altered Intercellular Communication	Former studies showed a significant role of macrophages in the process of the chronic inflammation leading to the aseptic loosening.	12087669
Inflammation	Altered Intercellular Communication	The presented results suggest the neutrophil's activation by the cytokines, which appear as a result of a local response to a foreign body, may be a factor initiating a chronic inflammation around the implant leading to the aseptic loosening.	12087669
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Soluble transferrin receptor (sTfR), ferritin, and sTfR/log ferritin index in anemic patients with nonhematologic malignancy and chronic inflammation.	12089189
Communicable Diseases, Inflammation	Altered Intercellular Communication	Because of the high glucose uptake of inflammatory cells, [18F]fluorodeoxyglucose (18F-FDG) is an appropriate tracer for the evaluation of suspected inflammation or infection.	12089487
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Inflammation, fibrinogen and thrombin generation in patients with previous myocardial infarction.	12091125
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Five years after myocardial infarction there was clear evidence of low-grade inflammation that was accompanied by an increase in thrombin formation.	12091125
Inflammation, Hemorrhage, Neoplasm Metastasis, Swelling, Dental Plaque	Altered Intercellular Communication	We found good healing of bleeding sites, no swelling and secondary bleeding, no inflammation, no plaque or crists.	12092000
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The remaining 292 specimens showed chronic inflammation, fibrosis, or normal mucosa.	12093640
Inflammation, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	To study neutrophil activation in circulation as a sign of systemic inflammation in preterm infants with respiratory distress syndrome.	12093944
Inflammation, Tissue injury, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	The observations demonstrate an early transient postnatal neutrophil activation indicative of systemic inflammation that may contribute to the tissue injury in preterm infants with respiratory distress syndrome.	12093944
Pyogenic granuloma	Altered Intercellular Communication	Pyogenic granulomata usually arise in the conjunctiva as a sequel of chronic lipogranulomatous inflammation.	12094321
Rheumatism	Altered Intercellular Communication	Inflammation itself may upregulate the expression of VEGF in rheumatic diseases.	12094393
Inflammation, Corneal Stroma	Altered Intercellular Communication	To report a case of caterpillar setae embedded in the corneal stroma and inferotemporal retina with minimal inflammation.	12095819
Inflammation	Altered Intercellular Communication	Intraretinal and corneal setae can be embedded with minimal inflammation and can be tolerated without need for surgical intervention.	12095819
Inflammation, Fever, CTCAE, Hypoxemia	Altered Intercellular Communication	All patients had fever above 38 degrees C, hypoxemia and a high inflammation reaction of.	12096495
Rupture, Angina, Unstable	Altered Intercellular Communication	Inflammation within vulnerable coronary plaques may cause unstable angina by promoting rupture and erosion.	12097534
Airway structure, Inflammation, Chronic Obstructive Airway Disease, ARCN1 gene	Altered Intercellular Communication	Because inflammation induces oxidative stress, exhaled hydrogen peroxide (H(2)O(2)), which is a marker of oxidative stress, may be used as a non-invasive marker of airway inflammation in chronic obstructive pulmonary disease (COPD).	12097763
Inflammation	Altered Intercellular Communication	The widely accepted model of pathogenesis suggests that ANCA activate cytokine-primed neutrophils within the microvasculature, leading to by-stander damage to endothelial cells, and rapid escalation of inflammation with recruitment of mononuclear cells.	12100039
Inflammation, Atherosclerosis	Altered Intercellular Communication	Genetic predisposition and chronic inflammation play the leading role in the early stages and in the development of atherosclerosis.	12101813
Fibrous, Fibrosis Assessment	Altered Intercellular Communication	Retroperitoneal fibrosis is an uncommon inflammatory condition in which the retroperitoneal tissue is transformed into a tight sheet of fibrous tissue.	12102285
Inflammation, Demographics Domain, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus	Altered Intercellular Communication	The patients were also classified as regards the presence of cardiovascular disease (CVD), diabetes mellitus (DM), and inflammation (CRP> or = 10 mg/l).	12105251
Inflammation, Malnutrition, Demographics Domain	Altered Intercellular Communication	In the whole patient group, the presence of CVD, DM, inflammation, and malnutrition (SGA >1) close to start of RRT all predicted poor outcome.	12105251
Albumins, Inflammation	Altered Intercellular Communication	S-albumin is more closely related to co-morbidity and inflammation than nutritional status in patients close to start of RRT.	12105251
Inflammation	Altered Intercellular Communication	Inflammation, hemostatic markers, and antithrombotic agents in relation to long-term risk of new cardiovascular events in first-ever ischemic stroke patients.	12105349
Inflammation, Thrombosis, Vascular Diseases	Altered Intercellular Communication	The measurement of markers of inflammation or thrombosis has been proposed as a method to improve the prediction of risk in patients with vascular disease.	12105349
Inflammation, Polycystic Ovary Syndrome	Altered Intercellular Communication	One hundred eleven patients were enrolled with equivalent visual acuity, inflammation, and PCO parameters.	12106719
Inflammation, Polycystic Ovary Syndrome	Altered Intercellular Communication	The second-generation silicone IOL was equivalent to the 3-piece AcrySof in patient satisfaction, visual function, inflammation, and PCO.	12106719
Cataract, Inflammation, Uveitis	Altered Intercellular Communication	Inflammation after implantation of hydrophilic acrylic, hydrophobic acrylic, or silicone intraocular lenses in eyes with cataract and uveitis: comparison to a control group.	12106723
Cataract, Inflammation, Uveitis	Altered Intercellular Communication	To compare the course of inflammation after small-incision cataract surgery with implantation of 1 of 3 types of foldable intraocular lenses (IOLs) in eyes with uveitis.	12106723
Inflammation, Uveitis	Altered Intercellular Communication	There were no significant differences in inflammation after implantation of foldable IOLs in uveitic eyes.	12106723
Intraocular inflammation	Altered Intercellular Communication	Regarding capsular biocompatibility, lens epithelial cell (LEC) outgrowth was inversely correlated with intraocular inflammation.	12106724
Inflammatory abnormality of the eye	Altered Intercellular Communication	Uveal and capsular biocompatibility depends on the intensity of ocular inflammation.	12106724
Inflammation	Altered Intercellular Communication	The greater the inflammation, the less the biocompatibility of hydrophilic and hydrophobic acrylic materials.	12106724
Gonadal structure, Gonadal Dysgenesis, Gonadoblastoma	Altered Intercellular Communication	Inhibin positivity in gonadal stroma and in gonadoblastoma may indicate hormonal activity causing advanced puberty in patients with XY gonadal dysgenesis.	12106750
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation after Hylan G-F 20 viscosupplementation of the knee : a report of six cases.	12107313
Pain Distress Question, Swelling, Inflammation, Hydrarthrosis	Altered Intercellular Communication	Mild pain or swelling at the site of injection may occur in up to 20% of patients, although severe local inflammation, warmth, and joint effusion are rare.	12107313
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Suplatast also decreased the percentage of eosinophils and concentrations of ECP in induced sputum, suggesting improvement in eosinophilic inflammation in patients with CVA.	12107601
Inflammation, Hypersensitivity	Altered Intercellular Communication	Lack of pronounced signs of inflammation and allergic reaction indicates that the above implant induces no significant pathological changes.	12107907
Inflammation, Necrotizing vasculitis, Necrosis	Altered Intercellular Communication	Nerve biopsy showed inflammation and necrosis of nerve arteries, which lead to the diagnosis of necrotizing vasculitis.	12108181
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Fever and laboratory signs of inflammation were inconstant.	12108340
airway disease, Inflammation	Altered Intercellular Communication	In some chronic airway diseases, the level of SLPI is decreased in sputum, leading to the continuation of neutrophil inflammation.	12108856
Inflammation	Altered Intercellular Communication	All patients fulfilled the ultrasonographic criteria of acute inflammation and had an APACHE II score > or =12.	12111069
Inflammation, Amoeba genus, Necrosis	Altered Intercellular Communication	Histopathological examination of these appendices demonstrated appendiceal ulceration, transmural mixed inflammation, haematophagous amoebic trophozoites and necrosis in all cases.	12111202
Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	Two appendices that appeared normal macroscopically demonstrated ulceration and inflammation that were confined to the mucosa and submucosa.	12111202
Allergic, Neurogenic Inflammation	Altered Intercellular Communication	The findings obtained suggest that SAM P10 is a useful animal model of aged human skin, because of its many similar morphological features, including the reduction of the cutaneous allergic response, represented by neurogenic inflammation via the axon reflex, and its decreased fibroblast proliferation.	12111405
Inflammation, Abnormality of the basal ganglia	Altered Intercellular Communication	Basal ganglia abnormalities were revealed by magnetic resonance imaging and at autopsy (as perivascular inflammation and microglial activation).	12112110
Adenocarcinoma, Inflammation	Altered Intercellular Communication	Forty-three consecutive specimens from 19 patients were reviewed to identify samples of squamous mucosa, Barrett's metaplasia, adenocarcinoma, and peritumoral inflammation.	12112555
Inflammation	Altered Intercellular Communication	No significant differences were noted in the number of single cells, anucleated cells, or in the amount of background inflammation found in aspirates of benign vs. malignant cystic squamous lesions.	12112808
Communicable Diseases, Inflammation, Anemia, Inflammatory disorder	Altered Intercellular Communication	Soluble transferrin receptor (sTfR) is reported to be a reliable marker for the diagnosis of iron deficiency, especially when iron metabolism is influenced by inflammatory disorders such as infection, chronic inflammation and cancer-related anemia.	12113300
Inflammation	Altered Intercellular Communication	One patient complained of chronic inflammation of the cervix, and another experienced rejection of the posterior mesh 6 months after the operation.	12113413
Inflammation, Liver Dysfunction	Altered Intercellular Communication	In single variable analysis, abnormal liver function tests, chronic inflammation, wall thickness, and number of stones were each predictive of longer operative time.	12113419
Inflammation, Bacterial Infections, Kidney Diseases	Altered Intercellular Communication	We tested whether measurements of PCT levels help distinguish the chronic inflammation in renal diseases from invasive bacterial infections.	12113602
Inflammation, Bacterial Infections, Kidney Diseases	Altered Intercellular Communication	CRP concentrations may be useful indicators for inflammation in patients with renal diseases, but have low specificity for the diagnosis of bacterial infection.	12113602
Tyrosine Transaminase Deficiency Disease	Altered Intercellular Communication	Other hormonal deficiencies may be present initially or may evolve after many years.	12113636
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	In recent years, the relation between biological markers of inflammation and prognosis in patients suffering from acute coronary syndromes has been investigated.	12113721
nervous system disorder, Pure Autonomic Failure	Altered Intercellular Communication	We hypothesized whether a similar mechanism would facilitate impaired neural transmission associated with neurological disease, and tested whether addition of external noise to baroreceptor signaling could improve blunted autonomic efferent responses to a postural challenge in patients with primary autonomic failure (PAF).	12113953
Klinefelter Syndrome	Altered Intercellular Communication	The hormonal profile raised the possibility of Klinefelter's syndrome, which was subsequently confirmed with karyotyping of 47 XXY.	12114306
Airway structure, Chronic obstructive pulmonary disease of horses	Altered Intercellular Communication	Long-term administration of macrolide antibiotics reduces sputum production in patients with chronic airway diseases, probably by inhibiting airway inflammation.	12114361
ARCN1 gene, Bronchitis	Altered Intercellular Communication	Patients with COPD classically have neutrophilic bronchial inflammation and raised airway concentrations of the neutrophil chemoattractant leukotriene B(4) (LTB(4)).	12114372
ARCN1 gene, Bronchitis	Altered Intercellular Communication	This small study suggests that a leukotriene synthesis inhibitor can produce modest reductions in some measures of neutrophilic bronchial inflammation in patients with COPD.	12114372
Inflammation	Altered Intercellular Communication	It is likely that platelets are also involved in inflammation.	12115179
Rheumatoid Arthritis	Altered Intercellular Communication	Assessment of proximal finger joint inflammation in patients with rheumatoid arthritis, using a novel laser-based imaging technique.	12115221
Pain Distress Question, Inflammation, Synovitis	Altered Intercellular Communication	At baseline and at followup after a mean of 6 weeks, clinical signs of synovitis, the joint circumference, and the degree of pain were assessed for each PIP joint in order to determine the clinical degree of inflammation.	12115221
Refractory anemias, Inflammation, Joints	Altered Intercellular Communication	At baseline, 72 PIP joints in the RA patients showed clinical signs of inflammation.	12115221
Inflammation, Joints	Altered Intercellular Communication	At followup, 45 PIP joints showed clinical improvement, 13 showed steady active inflammation, and 14 showed deterioration compared with the first visit.	12115221
Arthritis	Altered Intercellular Communication	Our data indicate that laser imaging may provide additional information in the early diagnosis of an inflammatory joint process and may prove particularly useful in assessing acute joint inflammation at followup.	12115221
Ventricular Dysfunction, Myocarditis, Edema, Traumatic injury	Altered Intercellular Communication	It is postulated that this patient's transient left ventricular dysfunction and ECG changes were caused by myocardial inflammation and oedema induced by operative trauma during pericardiectomy.	12117851
Necrotizing granulomatous inflammation, Granuloma, Palatine Tonsil	Altered Intercellular Communication	Ulcerations, masses and white patches characterized the tonsillar lesions; the pathological findings included caseous granuloma with positive acid-fast bacilli (AFB) in 5 patients and chronic granulomatous inflammation with negative AFB in one patient.	12118442
vascular inflammations, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	We conclude that C. pneumoniae LPS seropositivity may contribute to increased vascular inflammation in CHD patients, possibly even more pronounced when present in combination with H. pylori seropositivity.	12119204
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	Abnormal accumulation of beta-amyloid (Abeta) in Alzheimer's disease (AD) is associated with prominent brain inflammation.	12119423
Inflammation	Altered Intercellular Communication	Whereas earlier studies concluded that this inflammation is detrimental, more recent animal data suggest that at least some inflammatory processes may be beneficial and promote Abeta clearance.	12119423
Granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	In the first case, explorative laparotomy revealed granulomatous inflammation suggestive of tuberculosis.	12120010
Inflammation, Fibrosis Assessment, Lupus Erythematosus	Altered Intercellular Communication	The epidermis, infundibular and isthmus segments of follicles were relatively spared and lacked the lichenoid inflammation and fibrosis seen with lupus erythematosus.	12121404
Inflammation, Hemorrhage, Granuloma, Hypercholesterolemia, Granulation finding, Traumatic injury	Altered Intercellular Communication	This also explains why trauma (hemorrhage, granulation), cholesterol embolus, inflammation, metabolic imbalance may predispose to the formation of a granuloma, as well as the hypercholesterolaemia.	12122944
Inflammation	Altered Intercellular Communication	YKL-40 may also play a role in inflammation and degradation of connective tissue.	12124825
Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Crystalline silica may act as an immune adjuvant to increase inflammation and antibody production, and findings of occupational cohort studies suggest that silica exposure may be a risk factor for systemic lupus erythematosus (SLE).	12124868
Inflammation, Gangrene	Altered Intercellular Communication	The intensity of inflammation was determined pathologically grading from no inflammation to gangrenous appendicitis.	12125333
Inflammation	Altered Intercellular Communication	There were found eight specimens (17%) negative for inflammation dealing all with seronegative patients.	12125333
Gangrene, Acute inflammation	Altered Intercellular Communication	However, seropositive patients with acute inflammation are likely to suffer from purulent or gangrenous form.	12125333
Inflammation, Neoplasms, Congenital Abnormality, Hyperactive behavior, Autoimmune reaction	Altered Intercellular Communication	Possible underlying mechanisms are 1) hyperfunctioning tumors or nodules, 2) localized functioning thyroid tissue freed from autoimmune destruction, inflammation or tumor invasion, 3) congenital abnormality, 4) clusters of hyperactive follicular cells caused by long-term TSH and/or TSHRAb stimulation, 5) asymmetry, etc.	12126098
Inflammation, Chronic cholecystitis, Biliary calculi, Fever, CTCAE, Cholecystitis	Altered Intercellular Communication	Patients were assigned to one of two groups: (1) acute cholecystitis defined by the presence of gallstones, fever, leukocyte count >10(4), and inflammation on ultrasound or histology; (2) chronic cholecystitis that included all other symptomatic patients.	12127803
Acute Cholecystitis, Cardiovascular Diseases	Altered Intercellular Communication	Importantly, these risk factors-older men, presence of cardiovascular disease, male gender, acute cholecystitis, and severe inflammation-are determined preoperatively, permitting the surgeon to better inform patients about the conversion risk from LC to OC.	12127803
Inflammation	Altered Intercellular Communication	Histologic examination showed granulation tissue and chronic inflammation of the sac epithelium.	12130461
Inflammation, Intestinal Perforation	Altered Intercellular Communication	Laparotomy revealed two intestinal perforations of the jejunum and inflammation of the whole ileocecal region.	12130890
Inflammation	Altered Intercellular Communication	C-reactive protein (CRP) level is a sensitive marker of inflammation and a probable predictor of cardiovascular risk.	12131018
Inflammation, Coronary Artery Vasospasm	Altered Intercellular Communication	Both experimental and pathological studies suggest that immune response and inflammation may play an important role in the pathogenesis of coronary spasm.	12131020
Pneumonitis, Ulcer	Altered Intercellular Communication	Within 3 months of recognition of his conjunctival ulcers, newly recurrent pulmonary inflammation developed and serologies for cytoplasmic-pattern antineutrophil cytoplasmic antibodies (C-ANCA) became positive.	12131047
Inflammation	Altered Intercellular Communication	Cyclooxygenase enzymes catalyze a critical step in the conversion of arachidonic acid to prostaglandins, which are important mediators of acute and chronic inflammation.	12131767
Inflammation, Crohn Disease	Altered Intercellular Communication	Mucosal inflammation in clinically inactive Crohn's disease predicts forthcoming relapse.	12132790
Inflammation, Crohn Disease	Altered Intercellular Communication	Markers of mucosal inflammation in inactive Crohn's disease are lower in smokers than non-smokers.	12132790
Inflammation, Colonization	Altered Intercellular Communication	The degree of active inflammation increased with the increase in H. pylori colonization.	12135010
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	We suggest that EPX and myeloperoxidase, when applied in IBD, are the best eosinophil and neutrophil markers for studying GI inflammation.	12135031
Inflammation, Fibrosis Assessment, Fatty degeneration, Necrosis	Altered Intercellular Communication	Liver fibrosis, inflammation, and necrosis were graded according to the Knodell score, and steatosis as moderate to severe if more than 30% of hepatocytes were affected.	12135040
Inflammation, Hypertension, CTCAE, Corneal Endothelial Cell Loss, Atherosclerosis	Altered Intercellular Communication	Persistent endothelial damage and moderate inflammation may increase the risk of early atherosclerosis synergistically under the presence of hypertension in Japanese.	12135329
Inflammation, Congenital Abnormality	Altered Intercellular Communication	Ingrown nail is a deformity characterized by a transverse overcurvature of the lateral nail plate that causes nail fold inflammation.	12135509
Inflammation, atherosclerotic	Altered Intercellular Communication	C-reactive protein (CRP) is a nonspecific marker of inflammation that can be used as a marker for atherosclerotic risk.	12135817
Inflammation	Altered Intercellular Communication	All the patients subsequently had surgery which confirmed fibrovascular scar tissue in the rotator interval, around the biceps anchor and a variable degree of synovial inflammation of the glenohumeral capsule.	12136330
Inflammation, Corneal Neovascularization	Altered Intercellular Communication	Complete virus particles are not necessarily required in case of long-standing inflammation and corneal neovascularizations.	12136442
Inflammation	Altered Intercellular Communication	[Orbital exenteration in therapy-resistant painful scleritis-associated inflammation of orbital soft tissues].	12136445
Granulomatous inflammation, Granulomatosis with polyangiitis, Exophthalmos, Scleritis	Altered Intercellular Communication	Unilateral proptosis with anterior and posterior scleritis combined with granulomatous inflammation of orbital soft tissues may be the first symptom of Wegener's granulomatosis.	12136445
Inflammation, Colitis	Altered Intercellular Communication	Ischemic colitis was suspected and colonoscopy confirmed the presence of severe rectal and moderate sigmoid inflammation.	12136459
Inflammation	Altered Intercellular Communication	Damp conditions indoors favour the growth of microorganisms, and these contain several agents that may cause inflammation when inhaled.	12137243
HD Term Type, Inflammation, Anemia	Altered Intercellular Communication	Chronic inflammation is a common cause of severe anemia and hyporesponsiveness to recombinant erythropoietin (EPO) therapy in maintenance hemodialysis (HD) patients.	12138272
HD Term Type, Inflammation, Anemia	Altered Intercellular Communication	Subclinical inflammation is an important determinant of anemia in maintenance HD patients.	12138272
Anal Leiomyosarcoma, Orchitis	Altered Intercellular Communication	To report on a case of leiomyosarcoma of the testis that appeared to have arisen from a background of chronic testicular inflammation.	12138299
Communicable Diseases, Inflammation	Altered Intercellular Communication	CVC infection was suspected or possible when exit site inflammation and positive blood culture or organisms typical for CVC infection were observed.	12138333
Communicable Diseases, Inflammation	Altered Intercellular Communication	In another 6 episodes, CVC-related infection was assumed (local inflammation and gram-positive blood culture).	12138333
Inflammation, Asthma	Altered Intercellular Communication	One of the main findings in asthma is chronic inflammation of the airway.	12139887
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide may be a useful marker of airway inflammation in asthmatic children.	12139887
Vitreous Hemorrhage, Inflammation, Painless	Altered Intercellular Communication	Three days after surgery, she had painless loss of vision, minimal anterior chamber inflammation, and dense vitreous hemorrhage in the left eye.	12140041
Inflammation, Hypopyon	Altered Intercellular Communication	On the fourth postoperative day, significant anterior chamber inflammation developed with fibrin and a hypopyon.	12140041
Inflammation	Altered Intercellular Communication	Enlarged intramammary lymph node (LN) may be caused by inflammation [Arch.	12140156
Inflammation, Upper gastrointestinal hemorrhage	Altered Intercellular Communication	Underlying mucosal inflammation might promote UGI bleeding but is not likely to be the cause, making it a necessary superimposed factor such as NSAIDs or HP infection.	12141407
Inflammation	Altered Intercellular Communication	Multiple linear regression analysis showed significant associations between chronic inflammation or inflammatory activity, on the one hand, and the degree of proliferation in both the corpus and the antrum, on the other hand.	12141817
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The proliferative activity is related mainly to events associated with inflammation, while the expression of p53 in the antrum is associated with the degree of H. pylori infection.	12141817
Nonalcoholic Steatohepatitis, Inflammation, Steatohepatitis, Fibrosis Assessment, Disease, Fatty Liver Disease	Altered Intercellular Communication	Nonalcoholic steatohepatitis (NASH) is a disorder characterized by hepatic steatosis, inflammation, and fibrosis.	12143049
Hepatic inflammation	Altered Intercellular Communication	However, serum leptin was not an independent predictor of hepatic inflammation or fibrotic severity.	12143049
Steatohepatitis, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Furthermore, leptin levels correlate directly with the severity of hepatic steatosis but not with inflammation or fibrosis.	12143049
Intestinal metaplasia, Inflammation, Carditis	Altered Intercellular Communication	They were stained with hematoxylin and eosin and alcian blue-periodic acid Schiff for the detection of specialized intestinal metaplasia and inflammation of the cardiac mucosa (carditis) and with Warthin-Starry for H. pylori presence.	12143262
Autoimmune Diseases, Microunit per Milliliter	Altered Intercellular Communication	Thyroid-stimulating hormone (TSH) levels were higher in patients with thyroid autoimmunity (3.34 microU/ml, range 0.0-615.0 microU/ml) than in control subjects (1.84 microU/ml, range 0.0-149.0 microU/ml) (P < 0.001).	12145233
Inflammation, Diabetes Mellitus, Insulin-Dependent, Carotid Atherosclerosis	Altered Intercellular Communication	To evaluate whether low-grade inflammation contributes to early-stage advanced carotid atherosclerosis in young subjects with type 1 diabetes.	12145246
Granulomatous inflammation	Altered Intercellular Communication	PCR results were positive in 52 out of 54 cases whose skin biopsies showed granulomatous inflammation.	12145429
Necrotizing granulomatous inflammation	Altered Intercellular Communication	PCR on paraffin-embedded tissue is a highly sensitive and specific test for the diagnosis of CL, and detection of granulomatus inflammation is a highly reliable histopathologic finding in suspected cases.	12145429
Inflammation, Intestinal Diseases	Altered Intercellular Communication	Use of surrogate markers of inflammation and Rome criteria to distinguish organic from nonorganic intestinal disease.	12145798
Inflammation, Calculi, Dental Plaque	Altered Intercellular Communication	Efficacy was assessed by changes in gingival inflammation, plaque, calculus, and stain, while changes in clinical attachment levels and recession measurements provided safety data.	12146537
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	To examine the conjunctiva of patients with Sjogren's syndrome keratoconjunctivitis sicca (SS-KCS) and non-Sjogren's keratoconjunctivitis sicca (NS-KCS) for evidence of immune-based inflammation.	12147592
Conjunctivitis, Inflammatory cell infiltrate	Altered Intercellular Communication	The authors' findings indicate that patients with SS-KCS or NS-KCS have conjunctival inflammation manifested by inflammatory cell infiltrates and upregulation of expression in markers of immune activation.	12147592
Inflammation, Keratoconjunctivitis Sicca	Altered Intercellular Communication	Clinical symptoms of KCS may be more dependent on T-cell activation and resultant inflammation than previously believed.	12147592
Inflammatory abnormality of the eye	Altered Intercellular Communication	To investigate the expression and secretion of macrophage migration inhibitory factor (MIF) in human trabecular meshwork (HTM) and evaluate its role in ocular inflammation.	12147604
Hay fever, allergic inflammation	Altered Intercellular Communication	[The influence of a three-year preseasonal specific immunotherapy on selected parameters of allergic inflammation in pollinosis patients].	12148181
Eosinophilic disorder, allergic inflammation	Altered Intercellular Communication	Specific immunotherapy (SIT) can in some cases influence the course of allergic inflammation (eosinophilia and ECP concentration in peripheral tissue).	12148181
Eosinophilic disorder, allergic inflammation	Altered Intercellular Communication	Hence, SIT ameliorates allergic inflammation decreasing significantly activity of eosinophils in nasal mucosa measured as NALf eosinophilia and ECP concentration.	12148181
Inflammation, SERPINB3 wt Allele, Squamous cell carcinoma, Squamous intraepithelial lesion, Low Grade Squamous Intraepithelial Neoplasia, Herpes Simplex Infections, High-Grade Squamous Intraepithelial Lesions, Squamous metaplasia, Candidiasis	Altered Intercellular Communication	The pattern of cytologically detected lesion was as follows: within normal limit 13.8% (69), Chronic non-specific inflammation 82.8% (414), inflammation associated with Tricomonus vaginalis 1.6% (8), candidiasis 3.2% (16), Herpes simplex 0.6% (3), low grade squamous cells of undetermined significant (ASCUS) 0.6% (3), low grade squamous intraepithelial lesion (LSIL) 1.2% (6), high grade squamous intraepithelial lesion (HSIL) 0.6% (3), squamous cell carcinoma (SCC) 0.2% (1) and squamous metaplasia 1.4% (7).	12148392
Bronchitis	Altered Intercellular Communication	Bronchial inflammation analysed in bronchial biopsy specimens is only marginally reduced.	12149529
Mental disorders	Altered Intercellular Communication	The neurotransmitters dopamine and glutamate have been implicated in the prefrontal dysfunction associated with schizophrenic illness.	12150646
Inflammation, Dysplasia	Altered Intercellular Communication	Archival biopsies of 4 patient groups were selected, based on standard histochemistry: BE without inflammation, BE with inflammation, ulcerating BE, and BE with dysplasia.	12152167
Inflammation, Angina, Unstable, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	[Inflammation study in unstable angina and myocardial infarction without ST segment elevation.	12152386
Acute Coronary Syndrome, Inflammation	Altered Intercellular Communication	To analyse the inflammatory state in Acute Coronary Syndromes without ST-segment elevation by means of the value of the High-sensitivity C-reactive protein and other markers of inflammation.	12152386
Proctitis, Crohn Disease, Functional disorder	Altered Intercellular Communication	Anorectal functional disorders in the absence of anorectal inflammation in patients with Crohn's disease.	12153630
Airway structure, Mastocytosis, Bronchoconstriction	Altered Intercellular Communication	These data suggest that UNDW-induced bronchoconstriction may be independent of airway mast cells and that the mechanism of histamine-induced bronchoconstriction in systemic mastocytosis may be independent of airway inflammation, which is often present in asthmatics.	12153696
Inflammation, Choroiditis, Uveitis	Altered Intercellular Communication	Nine patients with active, vision-threatening serpiginous choroiditis who had progressive inflammation while on steroids and/or immunosuppressive agents other than alkylating agents treated at three tertiary care uveitis referral centers.	12153803
Communicable Diseases, Inflammation	Altered Intercellular Communication	The factors necessitating an early keratoplasty were heavy fungal load, deeper penetration of fungus, and possibly insufficient inflammation to combat infection.	12153808
Thrombophlebitis	Altered Intercellular Communication	Cerebral magnetic resonance imaging revealed an 8 mm thickening of the meninges over the left hemisphere, corresponding with a chronic inflammatory condition, and symptoms of left cavernous thrombophlebitis were detected.	12160977
Lambert-Eaton Myasthenic Syndrome, Disease	Altered Intercellular Communication	3 ACh release from normal NMJs was compared with that of NMJs of mice passively injected with IgGs obtained from patients with Lambert-Eaton myasthenic syndrome (LEMS), a disorder characterized by a compromised neurotransmitter release.	12163346
Inflammation, Psoriasis, Infection, Malignant Neoplasms, Hypersensitivity	Altered Intercellular Communication	Erythroderma is an inflammation of the skin, which can be triggered by various diseases as psoriasis, allergies, side effects of medication, infections or malignant tumors.	12163994
Inflammation, Intracranial Hypertension, Calcified (qualifier), Cessation of life, Hydrocephalus	Altered Intercellular Communication	Although brain calcifications alone have a benign prognosis, hydrocephalus is frequently associated with chronic inflammation and intracranial hypertension, together with a protracted clinical evolution, and may lead to patient deaths.	12164300
Uremia, Inflammation, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	This can be studied particularly well in patients with chronic renal failure who are on hemodialysis, as they show systemic inflammation due to uremia and dialysis while suffering from premature mortality secondary to rapidly progressing atherosclerosis.	12164877
Inflammation, Cardiac complication	Altered Intercellular Communication	We tested the hypothesis that the IL-10 genotype, by influencing the capacity to compensate for dialysis-induced systemic inflammation, determines the risk for cardiovascular complications.	12164877
Inflammation, Cardiovascular morbidity	Altered Intercellular Communication	The -1082A* allele, which is associated with low production of the cytokine IL-10 and elevated markers of systemic inflammation such as C reactive protein, was predictive for a higher cardiovascular morbidity (relative risk for cardiovascular events 2.76, 95% confidence interval 1.31 to 4.17, P = 0.004) compared to the -1082G* genotype.	12164877
Inflammation, Atherosclerosis	Altered Intercellular Communication	The data provide further evidence for a causal role of systemic inflammation for progressive atherosclerosis in dialysis patients.	12164877
Gastritis, Gastro-esophageal reflux disease with esophagitis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Reflux esophagitis facilitates low Helicobacter pylori infection rate and gastric inflammation.	12164958
Inflammation, Gland, Gastro-esophageal reflux disease with esophagitis	Altered Intercellular Communication	Grade of inflammation and glandular atrophy in the antrum and body were higher in patients in the non-reflux group compared with those in the reflux esophagitis group.	12164958
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Independent predictors of fibrosis were age (P = 0.001), past alcohol intake (P = 0.04), ALT (P = 0.002), serum insulin (P = 0.001) and portal inflammation (P < 0.001).	12164963
Inflammation, Anemia	Altered Intercellular Communication	Role of IL-10 for induction of anemia during inflammation.	12165551
Inflammatory Bowel Diseases, Inflammation, Anemia, Hyperferritinaemia	Altered Intercellular Communication	Our data demonstrate that IL-10 causes anemia in patients with inflammatory bowel disease which may be referred to the induction of imbalances in iron homeostasis by the cytokine, leading to hyperferritinemia and limited iron availability to erythroid progenitor cells, a condition typically seen in the anemia of chronic inflammation.	12165551
malignant disease, Neoplasms	Altered Intercellular Communication	In addition to malignant diseases, acute and chronic inflammations may elevate plasma levels of tumor markers CA 125 and carcinoembryonic antigen (CEA).	12165868
Inflammation, Specimen Source Codes - Abscess, Obstruction, Hernia, Crohn Disease, Non-Metastatic Carcinoma, Fibrous adhesion	Altered Intercellular Communication	The obstruction was due to fibrous adhesions in nine patients, metastases or primary carcinoma in seven, Crohn's disease in four, hernias in two, and inflammation or abscess in two.	12169282
Gastric Ulcer, CTCAE 5, Communicable Diseases, Inflammation	Altered Intercellular Communication	Infection by the virulent strain was found in 82% (40/55) of the patients, and among these, 89% (40/45) presented an increased degree of inflammation in the gastric mucosa, with a dense infiltration of leukocytes in the tissue, which probably favored the formation of gastric ulcer.	12170324
Inflammation	Altered Intercellular Communication	We concluded that the presence of the virulent strain is related to the development of an increased inflammation in the gastric mucosa.	12170324
Inflammation	Altered Intercellular Communication	Inflammation was maximal at the new squamocolumnar junction with > or = 2-fold increase in proinflammatory IL-8 and IL-1 beta expression.	12171950
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	In contrast, inflammation was minimal distally with a significant increase in anti-inflammatory IL-10 expression and 4/6 cancers occurred distally.	12171950
Gastroesophageal reflux disease, Inflammation, Infection caused by Helicobacter pylori, Gorontalo Language	Altered Intercellular Communication	Previous work has shown that it is associated with chronic inflammation attributable to either gastro-oesophageal reflux disease (GORD) or Helicobacter pylori infection.	12171955
Inflammation	Altered Intercellular Communication	Increasing age, male sex, chronic inflammation, and a high BRI emerged as significant independent associations with cardia IM.	12171955
Stomach Diseases, Superficial ulcer, Gastric Ulcer, CTCAE 5, Hiatal Hernia	Altered Intercellular Communication	The EGD results were normal, 18 (24.3%); thick gastric folds, 12 (16.2%); hiatal hernia, 12 (16.2%); erythema/inflammation, 11 (14.9%); erosions, 8 (10.8%); portal gastropathy, 3 (4.1%); and gastric ulcer, 1 (1.4%).	12172358
Granulomatous inflammation, Cutaneous Small Vessel Vasculitis, Necrotizing, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Systemic Vasculitis	Altered Intercellular Communication	Microscopic polyangiitis is a pauci-immune, necrotizing, small-vessel vasculitis without evidence of granulomatous inflammation.	12172362
Inflammation, Neoplasms	Altered Intercellular Communication	To assess the potential of measuring the calcium-binding protein calprotectin in faeces as a method of screening for alimentary inflammation and neoplasia.	12172403
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Calprotectin levels are elevated in inflammation and cancer but are not helpful in differentiating between these disorders.	12172403
Hematoma, Incontinence, Flu-Like Syndrome, CTCAE, Chronic anal fissure, Epididymitis, Otitis Externa	Altered Intercellular Communication	The patients with chronic anal fissure complained of incontinence of flatus (one severe case and eight mild cases), incontinence of faeces (five mild cases), anal haematoma (five cases), flu-like syndrome (three cases), an acute inflammation of external anal varices (two cases), epididymitis (one case) and haemorrhoid prolapse (one case).	12172405
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We concluded that colchicine has a mild antifibrotic effect which may be in inhibiting collagen formation since there was no effect on the inflammation that accompanies fibrosis.	12172901
Inflammation	Altered Intercellular Communication	Leukodepletion reduces CPB-associated inflammation and resultant end-organ injuries.	12173815
Inflammation, Specimen Source Codes - Abscess, Mammary fistula	Altered Intercellular Communication	Patients presenting with periareolar non-lactating inflammation, a periareolar inflammatory mass, abscess, mammary fistula, or nipple inversion were included in the study.	12174233
Inflammation, Fibrosis Assessment, IMMUNE SUPPRESSION	Altered Intercellular Communication	Transforming growth factor beta1 (TGFbeta1) has been reported to have important roles in unresolved inflammation, immune suppression, fibrosing processes, and angiogenesis.	12176809
Refractory anemias	Altered Intercellular Communication	TGFbeta1 is highly expressed in joints in RA and is considered to be a regulator of anti-inflammation in RA.	12176809
physiopathological	Altered Intercellular Communication	In spite of hormonal dysfunction, no pivotal mechanism leading to this pathology is known.	12177512
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Recent evidence implicates inflammation in the pathogenesis of coronary heart disease (CHD).	12177639
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	C-reactive protein is a moderately strong marker of risk of CHD in this cohort of middle-aged adults, consistent with the role of inflammation in the pathogenesis of CHD events.	12177639
Inflammation, atherosclerotic	Altered Intercellular Communication	The atherosclerotic hypothesis is rejected by foreign investigated while a conception of postrheumatic damage is discussed in the light of immune inflammation found in the calcinated valve.	12181809
Inflammation	Altered Intercellular Communication	The inflammation of the esophagus and duodenum mucosa was confirmed in a histopathological examination.	12182009
Cessation of life, Inflammation	Altered Intercellular Communication	The interactions of amyloid beta deposits, glial cell dynamics, inflammation and secreted cytokines, and the stress, recovery, and death of neuronal tissue are investigated.	12183120
Carbon Monoxide Poisoning, Upper Respiratory Infections, Somatoform Disorder, myocardial injury	Altered Intercellular Communication	The toxic myocardial injury followed by respiratory tract inflammations were predominant early complications and a psychoorganic syndrome was a predominant late complication in the oldest group of CO poisoned patients.	12183996
Inflammation	Altered Intercellular Communication	It describes environmental factors and the role of autoantibodies and autoaggressive cells in the bowel inflammation.	12184191
Saint Lucia, Cholecystitis	Altered Intercellular Communication	Our aim was to establish the outcome of LC in patients with AC on the basis of duration of the attack before surgery took place, the type of gallbladder inflammation, and patient sex.	12184905
Appendicitis, CTCAE	Altered Intercellular Communication	Chronic inflammatory conditions other than acute appendicitis were found in 9% of patients who underwent surgery after CT findings were interpreted as suspicious for appendicitis.	12185054
Communicable Diseases, Inflammation, Uveitis	Altered Intercellular Communication	Consequently, cases of uveitis with iris nodules were reviewed to identify clinical features that may help differentiate infection from non-infectious inflammation.	12185117
Inflammation	Altered Intercellular Communication	Serum ferritin and transferrin saturation (TS) may be influenced by the presence of inflammation.	12187081
Inflammation, Kidney Failure	Altered Intercellular Communication	Reversal of inflammation may be more effective than lipid-lowering therapy for renal failure in our patient.	12187114
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	Similar observations in Alzheimer's disease (AD) have lead to the hypothesis that chronic localized inflammation is an important element of AD pathogenesis, with significant neurodegenerative consequences.	12189211
Cataract, Inflammation	Altered Intercellular Communication	Postsurgical inflammation after bilateral cataract surgery using different intraocular lenses in each eye.	12189620
Hashimoto Disease, Inflammation, Autoimmune Disorder, CTCAE, Multiple Myeloma	Altered Intercellular Communication	Although autoimmune disorder might play an important role in lymphomagenesis in patients with Hashimoto's thyroiditis, it is not known whether the chronic inflammation that takes place in Hashimoto's thyroiditis stimulates the development of multiple myeloma.	12189648
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	Older age and male gender were also associated with inflammation and intestinal metaplasia of the cardia.	12190089
Crohn Disease, Inflammation	Altered Intercellular Communication	A positive response to infliximab in Crohn disease: association with a higher systemic inflammation before treatment but not with -308 TNF gene polymorphism.	12190096
Inflammation	Altered Intercellular Communication	Monocyte chemoattractant protein-1 (MCP-1) has been shown to act as a chemokine in the recruitment of monocyte/macrophages during inflammation states.	12190098
Inflammation	Altered Intercellular Communication	Challenge of the mucosal immune system by the commensal gut flora would then result in chronic inflammation.	12190167
Inflammation	Altered Intercellular Communication	Alternatively, increased permeability could be the result of inflammation.	12190167
Tumor necrosis, Inflammation, Crohn Disease	Altered Intercellular Communication	Inhibiting the proinflammatory cytokine tumor necrosis factor dramatically reduces gut inflammation and largely restores the gut barrier in Crohn's disease.	12190167
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	These data indicate that, in the setting of non-ST-elevation ACS, genetic variation at the IL-1 gene locus contributes to the changes in soluble markers of endothelial inflammation.	12193156
Inflammation, Dermoid Cyst	Altered Intercellular Communication	Clinical, radiological and pathological examination of periocular dermoid cysts: evidence of inflammation from an early age.	12194059
Cyst, Dermoid Cyst	Altered Intercellular Communication	Periocular dermoid cysts are common and leakage of the lipid or keratin contents leads to an inflammation-often asymptomatic-around the cyst, which may cause adherence of the dermoid cyst to neighbouring structures.	12194059
Inflammation, Sore to touch, Erythema	Altered Intercellular Communication	Clinical signs of inflammation at the time of clinic visit were relatively few, although 8% had some localised erythema and 7% had tenderness at the site of lesion.	12194059
Inflammation	Altered Intercellular Communication	In more than two-thirds of the excised cysts, pathological examination demonstrated various degrees of chronic inflammation, even in those cysts removed before the age of 5 years.	12194059
Inflammation, Dermoid Cyst, Cyst	Altered Intercellular Communication	Even if the patient does not have symptoms or signs of inflammation, most periocular dermoid cysts show histological evidence of inflammation due to leakage of the lipid and keratin contents from the cyst, the incidence being similar at all ages.	12194059
Inflammation, Uveitis	Altered Intercellular Communication	Provided the uveitis was well controlled for three months pre-operatively, additional pre-operative anti-inflammatory medications did not significantly affect (P = 0.842) post-operative inflammation.	12194565
Inflammation, Uveitis	Altered Intercellular Communication	Additional preoperative medications may not alleviate post-operative inflammation if uveitis is well controlled for at least three months before surgery.	12194565
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation was not present within the lymph nodes and the importance of this rare occurrence is discussed.	12195004
Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain score (VAS) and laboratory variables for inflammation were recorded.	12195628
Secondary malignant neoplasm of bone, Inflammation, Kidney Neoplasm, Secondary malignant neoplasm of liver	Altered Intercellular Communication	The presence of biological signs of inflammation, short time interval from renal tumor to metastases (<1 year), elevated neutrophil counts, liver metastases, bone metastases, patient performance status (PS), the number of metastatic sites, alkaline phosphatases and hemoglobin levels were predictive of survival outcome.	12196373
Inflammation, Fever, CTCAE, Abdominal Pain	Altered Intercellular Communication	In total, there were 118 SPOT injections in 113 patients; none had fever, abdominal pain, or any other signs or symptoms of inflammation develop.	12196769
Inflammation	Altered Intercellular Communication	A significantly higher (p = 0.001) positive culture rate was found for GB stones with acute cholecystits (47%) compared with that without inflammation (17%).	12197428
Inflammation, Hyperplasia	Altered Intercellular Communication	Inflammation and glandular proliferation in hyperplastic prostates: association with prostate specific antigen value.	12197626
Crohn Disease, Disorder of small intestine, Inflammation	Altered Intercellular Communication	The clinical manifestations of Crohn's disease (CD) are diverse, ranging from fibrostenosing small-bowel disease to colon-predominant inflammation.	12198692
ARCN1 gene, Airway structure	Altered Intercellular Communication	Stable COPD patients often have lower airway bacterial colonisation which may be an important stimulus to airway inflammation and thereby modulate exacerbation frequency.	12200518
Pneumonitis	Altered Intercellular Communication	Measurement of arterial Hb-CO may be a useful means of monitoring pulmonary inflammation.	12200522
ARCN1 gene, Asthma, Chronic Obstructive Airway Disease, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Inhaled corticosteroids (ICS) markedly reduce bronchial mucosal inflammation in asthma but whether they have an anti-inflammatory effect in airway tissue in chronic obstructive pulmonary disease (COPD) is unknown.	12200525
Typhlitis, Necrotizing, Peritonitis	Altered Intercellular Communication	However, in the further clinical course the patient became severely sick and developed a necrotizing ileocecal inflammation in combination with multiple perforations, 4-quadrants peritonitis and several other complications.	12200738
Inflammation	Altered Intercellular Communication	Diffuse FDG uptake often is associated with normal findings at colonoscopy, while segmental high uptake may imply inflammation.	12202714
Inflammation, Stenosis	Altered Intercellular Communication	Endoscopic findings included mild stricture and chronic inflammation of the mucosa.	12203081
Inflammation, Abnormal coagulation factor V activity	Altered Intercellular Communication	Cellular local immune reactions, as a consequence of chronic inflammation, and possibly abnormal motor activity in the narrowed esophagus, may explain the etiological agent or may be possible secondary factors that caused the EIPD.	12203081
Hyperplasia, Acute and chronic inflammation, Edema, Pneumonia	Altered Intercellular Communication	Varying amounts of organizing pneumonia, type 2 pneumocyte hyperplasia, edema, acute and chronic inflammation, and interstitial widening were seen.	12204055
Inflammation, Restenosis	Altered Intercellular Communication	An elevated preprocedural fibrinogen level should be considered as a stronger predictor for restenosis after coronary stenting, which might be associated with coagulation and inflammation.	12204810
Inflammation, Abdominal Pain	Altered Intercellular Communication	The inflammation produces a lesion which appears as a mass, and normally produces abdominal pain without any other significant clinical signs.	12207186
Inflammation	Altered Intercellular Communication	The blepharochalasis developed without any obvious inflammation of the eyelids over the past 10 years.	12207266
Inflammation, Intimal proliferation, Restenosis	Altered Intercellular Communication	AGEs-RAGE interaction in vessel wall may lead to inflammation, smooth muscle cell proliferation, and extracellular matrix production, culminating in exaggerated intimal hyperplasia and restenosis.	12208156
Retinal Detachment, Acquired Immunodeficiency Syndrome, Inflammatory abnormality of the eye, Glaucoma, CTCAE, Rubeosis iridis	Altered Intercellular Communication	A 25-year-old pregnant woman with AIDS, presented with a severe ocular inflammation in the right eye involving the choroid, retina, and the optic disk, which rapidly progressed to retinal detachment, iris neovascularization, and neovascular glaucoma.	12208267
Acquired Immunodeficiency Syndrome, Inflammatory abnormality of the eye, Eye Infection	Altered Intercellular Communication	Although ocular infection with ocular paracoccidioidomycoses is rare, this diagnosis should be considered when investigating ocular inflammation in a patient with AIDS.	12208267
Cessation of life, Inflammation	Altered Intercellular Communication	Several of these factors suggest that inflammation may play a part in the excess risk of death.	12208794
Inflammation	Altered Intercellular Communication	Theoretically, there could be differences in the features of synovial inflammation between various joints as a result of mechanical factors, differences in innervation, and other factors.	12209505
Inflammation	Altered Intercellular Communication	The results of this study show that the inflammation in one inflamed joint is generally representative of that in other inflamed joints.	12209505
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Clinically, patients present with recurrent episodes of fever in conjunction with localized inflammation at various sites.	12209524
Inflammation, Familial Mediterranean Fever	Altered Intercellular Communication	Its presence in the population of persons of Mediterranean ancestry and the short duration of the attacks of inflammation can lead to a fallacious diagnosis of FMF.	12209523
Inflammation, Fibrosis Assessment, Atrophic	Altered Intercellular Communication	A year later, histology showed that the grade of atrophy had decreased in 42%, probably due to the regression of inflammation, and increased in 10% of cases, but interstitial fibrosis (expressed as collagen fibre content) was practically unchanged.	12210062
Gastrointestinal inflammation	Altered Intercellular Communication	Recruitment of peripheral leukocytes to intestine is an essential process for intestinal inflammation.	12210077
Presenile dementia, Inflammation	Altered Intercellular Communication	Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia Aging Study.	12210786
Presenile dementia, Inflammation	Altered Intercellular Communication	We evaluated the long-term prospective association between dementia and high-sensitivity C-reactive protein, a nonspecific marker of inflammation.	12210786
Pleural Effusion, CTCAE, Pleurisy	Altered Intercellular Communication	The detection of D -dimer in pleural fluid may reflect the extent of pleural inflammation and be helpful in the differential diagnosis of pleural effusion.	12212257
Cyst, Adenoma, Angioma, Granuloma	Altered Intercellular Communication	Benign oral lesions were classified into nine groups as follows: epithelial proliferating lesions (n = 234); fibroma-like lesions (n = 150); cysts and cyst-like lesions of the minor salivary glands (n = 140); ranulas (n = 64); angiomas (n = 62); inflammation/ulcer/granulation lesions (n = 56); pyogenic granulomas (n = 44); pleomorphic adenomas (n = 23); and others (n = 19).	12212602
Dental Plaque, Data types - Address, Neuronal loss in central nervous system	Altered Intercellular Communication	The neuronal loss and synaptic transmission deficit in AD may therefore depend on intraneuronal accumulation of A beta/CTF rather than on extracellular plaque formation.	12212794
Orbital swelling, Inflammation, Dirofilariasis	Altered Intercellular Communication	Australian ophthalmologists should consider dirofilariasis as part of the differential diagnosis of orbital swelling and inflammation.	12213168
Adenocarcinoma, Adenoma, Chronic inflammation, Acute Cholecystitis	Altered Intercellular Communication	Pathological diagnoses in nine patients were two acute cholecystitis, four chronic inflammation, one adenoma and two adenocarcinoma.	12213365
Inflammation, Lithiasis	Altered Intercellular Communication	Autopsy confirmed parotid gland inflammation and pre-existing ductal lithiasis.	12215051
Tears body substance, Lacrimal Duct Obstruction, Otitis Externa	Altered Intercellular Communication	The secretion of docetaxel in tears may be a mechanism for canalicular inflammation and tear drainage obstruction, which are known to occur as an adverse effect of the drug.	12215091
Pain Distress Question, Inflammation, Soft Tissue Injuries, Ecchymosis	Altered Intercellular Communication	Ankle sprain is a common acute soft-tissue injury that often results in pain, inflammation, and ecchymosis.	12216965
Inflammation, Neoplasms	Altered Intercellular Communication	Existence of inflammation close to the tumor is interesting to emphasize.	12217767
Intestinal metaplasia, Inflammation, Pancreatic aplasia, Certified Midwife	Altered Intercellular Communication	Hematoxylin and eosin-stained slides were evaluated by two pathologists for the following histologic details: minimal and maximal length of cardiac mucosa (CM) and oxyntocardiac mucosa (OCM, mixture of cardiac and fundic glands), degree of inflammation in CM and OCM, and presence of intestinal metaplasia or pancreatic metaplasia.	12218577
Inflammation	Altered Intercellular Communication	There was no intimal, medial, or adventitial inflammation.	12218982
Inflammation, Manufactured sign	Altered Intercellular Communication	Predictive values of age, cervical signs, and inflammation on GS (more than 30 polymorphonuclear leukocytes per 1000x field) were calculated.	12220782
Communicable Diseases, Hemorrhage, Inflammation	Altered Intercellular Communication	Age, cervical signs (mucopus, induced bleeding), and inflammation on endocervical GS were independently associated with infection.	12220782
Communicable Diseases, Inflammation, Infection, MUCOPURULENT CERVICITIS	Altered Intercellular Communication	Inflammation on endocervical GS was the sole indicator of infection in 79 of 520 (15%) infections, but was insensitive in the absence of mucopurulent cervicitis (sensitivity, 26%; PPV, 21%).	12220782
Inflammation	Altered Intercellular Communication	Various mechanisms including direct compression, inflammation, vascular compromise, and mechanical stretch of the posterior primary ramus may play a role in denervation.	12221358
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Interleukin (IL)-12, being a major cytokine that induces T helper (Th) 1 differentiation and inflammatory response, has been postulated to be an important mediator of synovial inflammation in rheumatoid arthritis (RA).	12223112
Genitourinary system, Trichomonas Infections, Solitary Osseous Plasmacytoma	Altered Intercellular Communication	Clinical and laboratory studies were made in 2259 persons by using serological assays, including cultural and bacterioscopic assays in 1824 and 363 persons, respectively, in order to indicate Trichomonas infection among men, women, and 2-15-year-old children who had chronic inflammation of the urogenital system, as well as among children aged 2 months to 16 years who had a severe somatic disease.	12224263
Parasitic Diseases	Altered Intercellular Communication	[Parasitic diseases are a risk factor of inflammations of the small pelvis organs.	12224263
Inflammation, Dirofilaria	Altered Intercellular Communication	In the latter case, the location of Dirofiliria provoked prolonged (7-month) erysipelatous inflammation.	12224272
Inflammation, Neoplasms	Altered Intercellular Communication	During angiogenesis, the matrix metalloproteinase (MMP) family of tissue enzymes contributes to normal (embriogenesis or wound repair) and pathologic tissue remodeling (chronic inflammation and tumor genesis).	12225633
Inflammation, Whole-Body Irradiation, Traumatic	Altered Intercellular Communication	Acute inflammation plays a significant role in the pathophysiology of traumatic brain injury (TBI).	12225653
Inflammation, Wheezing	Altered Intercellular Communication	To determine the cell profile of BAL from infants with severe recurrent wheezing who were not acutely ill at the time of investigation, suggesting an ongoing inflammation.	12226015
Inflammation, Wheezing	Altered Intercellular Communication	Neutrophil-mediated inflammation in the airways appears to better characterize severe recurrent wheezing in children < 3 years old.	12226015
Inflammation, Virus Diseases, Data types - Address, Trauma, Nervous System	Altered Intercellular Communication	Diet, aluminum, and viral infections may increase the prevalence of AD by eliciting inflammation, which may cause the neurological damage that results in AD.	12226537
Inflammation, Arthritis, Reactive	Altered Intercellular Communication	Laboratory tests showed evidence of severe inflammation, but cultures of blood, urine and joint fluid specimens were negative, as were tests for autoantibodies and serologic tests for organisms known to cause reactive arthritis.	12226788
Inflammation	Altered Intercellular Communication	[Analysis of the inflammation reaction and selected indicators of immunity in patients with an infected diabetic ulcer].	12226915
Inflammation, diabetic foot infection	Altered Intercellular Communication	The aim of our study was to assess presence of the chronic inflammation and specific immune responses, both humoral and cellular in patients with diabetic foot infection.	12226915
Inflammation	Altered Intercellular Communication	It is necessary to assess the sufficiency of immune system activation with respect to chronic inflammation in next research.	12226915
Airway structure, Airway Obstruction, Respiratory Hypersensitivity	Altered Intercellular Communication	Asthma is a chronic condition that affects approximately 14 million persons in the United States and is characterized by airway inflammation, reversible airway obstruction, and airway hyperresponsiveness to a variety of triggers.	12227438
Inflammation	Altered Intercellular Communication	The patients were registered as incident cases if the onset of the joint inflammation was between 1 May 1999 and 1 May 2000.	12228162
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays an important role in the initiation and progression of atherosclerosis and in the pathogenesis of acute cardiovascular events.	12228781
Acute Coronary Syndrome, Inflammation	Altered Intercellular Communication	In patients with clinically stable conditions who have a positive history for acute coronary syndromes before age 50 years, plasma levels of CRP higher than 1.6 mg/L are predictors of future coronary events and therefore indicate the role of underlying chronic inflammation for the clinical course of CAD.	12228781
Communicable Diseases, Inflammation, Restenosis	Altered Intercellular Communication	Preliminary studies of infection or inflammation in restenosis report varied results.	12228787
Inflammation, Restenosis	Altered Intercellular Communication	CRP, a marker of inflammation, was not associated with an increased risk of restenosis.	12228787
Communicable Diseases, Inflammation, Tissue injury	Altered Intercellular Communication	During the acute phase response (APR) to tissue injury or infection, the liver is responsible for the level of mediators such as cytokines required at the site of inflammation and providing the essential components for wound healing and tissue repair.	12228891
Inflammation	Altered Intercellular Communication	Prospective randomized trials show that maintaining gut integrity is equally as important as placing the pancreas at rest while inflammation within the gland resolves.	12230318
Inflammation, Pancreatitis, Feeding Intolerance, Adverse Event	Altered Intercellular Communication	Total parenteral nutrition should be reserved only for the patient with severe pancreatitis, initiated 4 to 5 days after peak inflammation in whom intolerance to enteral feeding has been shown and/or enteral access cannot be obtained.	12230318
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Collectively, our data provide evidence supporting dietary supplementation of n-3 PUFA, which in turn may have a beneficial effect of slowing and reducing inflammation in the pathogenesis of degenerative joint diseases in man.	12230798
Refractory anemias, Inflammation	Altered Intercellular Communication	These data suggest that SASP may function to reduce inflammation in RA through the effects of its metabolite SP to reduce the secretion of the inflammatory chemokines IL-8, GROalpha, and MCP-1.	12231210
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	Inflammation needs to be considered in the pathogenesis of acquired aortic stenosis, irrespective of the primary valve anomaly.	12231589
Inflammation, Dislocations	Altered Intercellular Communication	Local inflammation occurred in one patient and dislocation of the catheter in another patients.	12232647
Inflammation, Atrophic, Fatty infiltration	Altered Intercellular Communication	Quantitative and qualitative MRI analysis of the 3 muscle groups of the 2 thighs included fatty infiltration, atrophy, inflammation, and the type and distribution of the lesions.	12233884
Inflammation	Altered Intercellular Communication	Inflammation as the sole abnormality was preferentially encountered in PM (p = 0.05).	12233884
Inflammation, Neoplasms	Altered Intercellular Communication	Additionally, we observed centrosome hyper-amplification and multipolar mitoses not only in the tumor but also in the early stages of inflammation.	12234059
Inflammation	Altered Intercellular Communication	It may prevent a potentially hazardous reduction of immunosuppression in persistent inflammation.	12234276
palladium, Inflammation	Altered Intercellular Communication	Chronic inflammation, as reflected by elevated CRP levels, is frequent in patients starting PD and independently contributes to an increased incidence of CVE in this population.	12234314
Airway structure, Inflammation, Fibrosis Assessment, Respiratory Failure	Altered Intercellular Communication	Cystic fibrosis (CF), characterized by chronic airway infection and inflammation, ultimately leads to respiratory failure.	12234487
Inflammation, Herpes zoster disease, Necrosis	Altered Intercellular Communication	Histopathologically, the skin lesions of acute herpes zoster (AHZ) are characterized by epidermal necrotic vesicles with inflammation.	12234710
Inflammation, Necrosis	Altered Intercellular Communication	Increased expression of iNOS is consistent with the hypothesis that high level of NO induced by iNOS may be associated with the epidermal necrosis with inflammation seen in the skin lesions of AHZ.	12234710
Stomach Carcinoma, Gastritis	Altered Intercellular Communication	We correlated H pylori babA2, vacuolating toxin (vacA), and cytotoxin associated gene A (cagA) genotypes with the severity of gastric inflammation and epithelial cell turnover in a group of Chinese patients from an area with a high incidence of gastric cancer.	12235067
Communicable Diseases, Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	These findings suggest that colorectal cancer patients treated with raltitrexed may develop drug-related systemic inflammation, which may be difficult to discriminate from infection.	12237767
Inflammation, Hyperuricemia, Congestive heart failure	Altered Intercellular Communication	Congestive heart failure is associated with hyperuricemia and elevations in the levels of circulating markers for inflammation.	12238311
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	The liver dialysis device used was found to be associated with activation of both coagulation and fibrinolytic pathways, activation of inflammation reactants, and an increase in sL-selectin levels.	12239938
Gastritis	Altered Intercellular Communication	Interleukin-1 beta (IL-1 beta) plays an important role in gastric inflammation and physiology.	12239970
Inflammation, Myalgia	Altered Intercellular Communication	Discontinuing the offending drug will usually result in rapid diminution of muscle pain and inflammation and improve muscle strength.	12240878
Metabolic Diseases, Family history	Altered Intercellular Communication	Our results support the suggestion that the GH-IGF-I axis plays an important role in the evolution of hormonal and metabolic derangement in non-obese FH women.	12240900
Tissue damage, Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Vasculitis is a condition characterised by inflammation around vessel walls, leading to secondary tissue damage for which the underlying molecular mechanisms are poorly understood.	12241658
Inflammation, Vasculitis, CTCAE, Edema, Pain Distress Question	Altered Intercellular Communication	Activation of the contact system could play a part in the pathogenesis of vasculitis, and explain the inflammation, pain, vasodilatation, and oedema seen in patients.	12241658
Inflammation, Neurologic Deficits	Altered Intercellular Communication	Do S100beta protein level increases due to inflammation during cardiopulmonary bypass occur without any neurological deficit?	12243436
Airway structure, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Early airway infection, inflammation, and lung function in cystic fibrosis.	12244003
Airway structure, Inflammation, Signs and Symptoms, Respiratory, Cystic Fibrosis	Altered Intercellular Communication	To determine the relation between lower airway infection and inflammation, respiratory symptoms, and lung function in infants and young children with cystic fibrosis (CF).	12244003
Airway structure	Altered Intercellular Communication	No relation was identified between airway inflammation and lung function.	12244003
Airway structure, Communicable Diseases, Coughing	Altered Intercellular Communication	Independent of either infection status or airway inflammation, those with daily cough had lower lung function than those without respiratory symptoms at the time of BL (mean adjusted FEV(0.5) 195 ml and 236 ml respectively).	12244003
Airway structure, Signs and Symptoms, Respiratory	Altered Intercellular Communication	In young children with CF, both respiratory symptoms and airway infection have independent, additive effects on lung function, unrelated to airway inflammation.	12244003
Inflammation, Damage	Altered Intercellular Communication	Multiple sclerosis is characterized morphologically by the key features demyelination, inflammation, gliosis and axonal damage.	12244078
Allergic, Inflammation, Psoriasis, Dermatitis, Irritant, Pathology, Dermatitis, Atopic	Altered Intercellular Communication	Further than being among the main responsible for skin ageing, the 1O2 is involved in the genesis of many topical pathologies such as allergic and irritant dermatitis, atopic dermatitis, inflammation, psoriasis and sunburns.	12244285
Structure of respiratory bronchiole, Bronchiolitis, Hepatopulmonary Syndrome	Altered Intercellular Communication	Diffuse panbronchiolitis is a clinical pathologic condition characterized by chronic inflammation of respiratory bronchioles, with clinical features that position it as a differential diagnosis among the sinopulmonary syndromes.	12244337
Adrenal Cortex Hormones, Inflammation, Laryngeal Edema	Altered Intercellular Communication	Short-term administration of corticosteriods is sometimes indicated for professional voice users experiencing laryngeal edema and/or inflammation.	12269626
Mastitis, Breast Carcinoma	Altered Intercellular Communication	Two hundred seventy-seven patients with nonpuerperal breast inflammation were prospectively screened for breast cancer within 1 year after mastitis was diagnosed.	12270566
Ischemia, Giant Cell Arteritis	Altered Intercellular Communication	Inflammation-induced angiogenic activity may play a compensatory role for ischemia in patients with giant-cell arteritis.	12270860
Inflammation, Keratosis	Altered Intercellular Communication	Both patients had similar numbers of actinic keratoses on symmetric areas and treated only one side with imiquimod cream 2 to 3 times per week with frequent rest periods to avoid inflammation.	12271285
Psoriasis, Cutaneous, Dermatitis	Altered Intercellular Communication	Psoriasis is a persistent cutaneous disease characterized by skin inflammation and infiltration of immunocytes such as lymphocytes and monocytes/macrophages, concomitant with abnormal epidermal hyperproliferation.	12271361
Inflammation, Malnutrition, Anemia, Hypoalbuminemia	Altered Intercellular Communication	Our findings suggest that inflammation is a contributor in the development of hypoalbuminaemia and anaemia in haemodialysis patients as well as malnutrition and inadequate dialysis.	12296612
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Mediators of inflammation are down-regulated while apoptosis is up-regulated in rheumatoid arthritis synovial tissue by polymerized collagen.	12296865
Refractory anemias, Inflammation	Altered Intercellular Communication	Perhaps this mechanism could contribute to inhibit outgrowth of pannus formation and to down-regulate inflammation of joints in patients with RA.	12296865
Hepatobiliary Disorder, Hepatic inflammation, Fibrosis Assessment	Altered Intercellular Communication	Patients without underlying liver disease (n = 15): Hepatic inflammation was seen in only 8% but fibrosis was found in 36% of compound heterozygous patients.	12296962
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	Patients with underlying disease (n = 10): In compound heterozygous patients, 77% had hepatic inflammation and 88% fibrosis.	12296962
Airway structure, Asthma	Altered Intercellular Communication	These results suggest the presence of a distinct subgroup of patients with mild to moderate asthma who have predominantly neutrophilic airway inflammation and who respond less well to treatment with inhaled corticosteroids.	12324674
Inflammation	Altered Intercellular Communication	Thoracoscopy revealed no apparent abnormalities and a pleural biopsy specimen showed only non-specific inflammation.	12325337
Mycoses	Altered Intercellular Communication	Hormone changes which occur during this age might play a role in the pathogenesis of fungal infection.	12350033
Inflammation, Neoplasms, Malignant Neoplasms	Altered Intercellular Communication	To investigate whether dynamic CT enables quantitative differentiation between inflammation, benign tumors, and malignant tumors in oral and maxillofacial regions.	12350403
Inflammation, Malignant Neoplasms, Neoplasms	Altered Intercellular Communication	PH was highest in inflammation, followed by malignant tumors and benign tumors.	12350403
Inflammation, Neoplasms, Malignant Neoplasms	Altered Intercellular Communication	TT was significantly longer in benign tumor cases compared with malignant tumor and inflammation cases.	12350403
Inflammation, Malignant Neoplasms, Neoplasms	Altered Intercellular Communication	PR for malignant tumor and inflammation were between the artery and vein phase, and that for benign tumor was beyond the vein phase.	12350403
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Inflammation occurs in defunctioned rectums in patients without inflammatory bowel disease.	12352238
Inflammation, Septicemia	Altered Intercellular Communication	In 1 patient BCG inflammation and in 2 others severe septicemia developed after the first perfusion.	12352398
Inflammation, Edema	Altered Intercellular Communication	Changes in the urothelium were classified histologically into 7 subgroups according to the degree of edema and inflammation.	12352458
Post-Traumatic Stress Disorder, Traumatic injury	Altered Intercellular Communication	Recent data suggest that sex hormones may play a role in regulating posttraumatic immunosuppression, leading to gender-based differences in outcome after injuries.	12352476
Inflammation, Tissue injury	Altered Intercellular Communication	Interleukin-6 (IL-6) is a multifunctional cytokine playing a crucial role in inflammation and tissue injury.	12352619
Communicable Diseases, Inflammation	Altered Intercellular Communication	Selective use of antibiotics limited to patients with signs of lacrimal sac inflammation appears sufficient to prevent soft tissue infection after DCR.	12352818
Graves Disease, Euthyroid Sick Syndromes	Altered Intercellular Communication	In patients with Graves' disease, serum levels of TNF-alpha have been reported to be elevated and administration of TNF-alpha to humans has been shown to induce hormonal alterations resembling those seen in the nonthyroidal illness syndrome.	12354134
vascular inflammations, Restenosis	Altered Intercellular Communication	Vascular inflammation and percutaneous transluminal angioplasty of the femoropopliteal artery: association with restenosis.	12354979
vascular inflammations, Restenosis	Altered Intercellular Communication	The extent of vascular inflammation as measured by means of acute-phase reactants before and after PTA of the femoropopliteal artery is associated with 6-month restenosis.	12354979
Inflammation, Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	The 55 cases were categorized histologically into four grades: grade 1, interstitial inflammation without fibrosis (n = 6); grade 2, interstitial inflammation predominating over fibrosis (n = 16); grade 3, fibrosis predominating over inflammation (n = 5); and grade 4, fibrosis only (n = 28).	12355005
Inflammation, Thickened, Hyperkeratosis, Nail Loss, Alopecia, CTCAE	Altered Intercellular Communication	Animals of 4 transgenic lines (HLA-DR2.Ab(0), DR4.Ab(0), DQ6.Ab(0), and DQ8.Ab(0)) developed severe toe inflammation accompanied by progressive bone resorption, hyperkeratosis, alopecia, loss of nails, and shortening and thickening of the distal phalanges.	12355495
Inflammation, Osseous metaplasia, Retinal Detachment, Drusen, Retinal pigment epithelial hyperplasia	Altered Intercellular Communication	Specific histopathologic features noted in specimens with osseous metaplasia were the presence of retinal detachment, gliosis, retinal pigment epithelial hyperplasia, drusen, epiretinal membrane, fibrovascular proliferation and inflammation.	12355691
Osteogenesis, Drusen, Inflammation, Calcinosis	Altered Intercellular Communication	Drusen with calcification or ossification (5 of 8), fibrovascular proliferation in the vitreous (5 of 8) and active inflammation (4 of 8) were the other associated histologic features.	12355691
Intraocular inflammation	Altered Intercellular Communication	During the treatment period, the patient did not have clinical evidence of intraocular inflammation.	12356117
Macular Edema, Cystoid, Crohn Disease, Intraocular inflammation	Altered Intercellular Communication	Bilateral phakic cystoid macular edema may be associated with Crohn's disease, despite the lack of clinical evidence of intraocular inflammation.	12356117
Inflammation	Altered Intercellular Communication	Further, hemodialysis membrane bioincompatibility can contribute to increased oxidative stress and prevalence of inflammation.	12356187
Intraocular inflammation, Retinitis, Glaucoma, CTCAE, Morbidity - disease rate	Altered Intercellular Communication	Immune recovery in the setting of inactive cytomegalovirus retinitis can result in intraocular inflammation severe enough to cause angle closure glaucoma and profound ocular morbidity.	12358297
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Contribution of interleukin 17 to human cartilage degradation and synovial inflammation in osteoarthritis.	12359166
Scleritis, Orbital Pseudotumor	Altered Intercellular Communication	A 28-year-old female presented with nodular scleritis in the right eye and left orbital inflammation lasting 1 year.	12359619
Abscess of skin AND/OR subcutaneous tissue, Myalgia, Inflammatory abnormality of the eye, Fever, CTCAE	Altered Intercellular Communication	The patient initially responded to systemic steroids, but then ocular inflammation became more severe, associated with onset of fever, myalgias, and elevation of the erythrocyte sedimentation rate, accompanied by formation of multiple cutaneous abscesses.	12359619
Scleritis, Orbital Pseudotumor	Altered Intercellular Communication	Ocular and extracutaneous involvement rarely occur, but the disease should be included in the differential diagnosis of scleritis and orbital inflammation.	12359619
Inflammation, Malaria, Growth Disorders	Altered Intercellular Communication	Our results are consistent with the notion that the nutritional inadequacies causing stunting also impair host immunity, thus increasing the degree to which malaria is associated with decreased concentrations of hemoglobin, with increased inflammation, and with increased iron demand in developing erythroblasts.	12359821
Scleroderma , Gastrointestinal dysmotility, Systemic Scleroderma	Altered Intercellular Communication	Defects in enteric excitatory neurotransmission have been proposed to underlie the gastrointestinal dysmotility associated with scleroderma (systemic sclerosis).	12360477
Gastrointestinal dysfunction, Scleroderma	Altered Intercellular Communication	Functional antibodies specifically inhibiting M3-muscarinic receptor-mediated enteric cholinergic neurotransmission may provide a pathogenic mechanism for the gastrointestinal dysfunction seen in patients with scleroderma.	12360477
Inflammation, Neoplasms	Altered Intercellular Communication	Endobronchial biopsies and bronchioalveolar lavage showed no evidence of neoplasm or inflammation.	12362286
Inflammation, Prostate Cancer Outcomes Study, Fever, CTCAE, Polycystic Ovary Syndrome	Altered Intercellular Communication	We report on a 28-year old patient with polycystic ovary syndrome (PCOS) who presented with fever and laboratory markers of inflammation.	12369659
Inflammation, Cerebral Ischemia, Acute Cerebrovascular Accidents	Altered Intercellular Communication	As platelet endothelial cell adhesion molecule-1 (PECAM-1) is one of key mediators of transendothelial migration of leucocytes during inflammation, and inflammatory reaction is observed in cerebral ischaemia, we decided to determine the levels of soluble PECAM-1 (sPECAM-1) in serum and cerebrospinal fluid (CSF) of patients with acute stroke.	12371923
Airway structure	Altered Intercellular Communication	Asthma is characterized by eosinophilic airways inflammation with elevated levels of IL-4, IL-5 and sICAM-1, and reduced levels of IL-10 and IFN-gamma.	12372131
Airway structure	Altered Intercellular Communication	Airway inflammation and functional changes after exposure to different concentrations of isocyanates.	12373274
Inflammatory dermatosis	Altered Intercellular Communication	To investigate the role of these APCs in T-cell immune-mediated inflammation, we examined the distribution and numbers of epidermal and dermal CD1a(+) dendritic cells (DCs), factor XIIIa(+) dermal DCs, and CD68(+) macrophages in five T-cell-mediated inflammatory skin diseases.	12373334
Sepsis, Balanitis	Altered Intercellular Communication	The penile inflammation rapidly extended posteriorly to involve the scrotum and perianal tissues, inferiorly to involve the thighs, and superiorly up the lower abdominal region within the next 36 h, and he died from sepsis on day 27.	12373358
Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	Elderly patients appear prone to develop overwhelming post-bypass inflammation and organ dysfunction.	12373472
Inflammation	Altered Intercellular Communication	Pseudodiverticulosis of the esophagus is a very rare disease which arises from ductal dilatation of the mucosal glands during chronic inflammation of the esophagus.	12373638
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We found that TS was usually due to an increase in the width of the mucosa as a result of the fibrosis associated with the chronic inflammation.	12375067
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	chronic inflammation and fibrosis are responsible for the narrowing of trachea in TS patients, (b).	12375067
Pneumonitis	Altered Intercellular Communication	Three major MAP kinases (MAPKs), including extracellular signal-regulated kinase (ERK), c-jun N-terminal kinase (JNK), and p38 kinase (p38 MAPK), are involved in the regulation of lung inflammation and injury.	12375272
Inflammation, Lung Injury, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	This is the first study to suggest that MAPKs may be associated with the regulation of inflammation and lung injury in IPF.	12375272
Airway structure	Altered Intercellular Communication	These results show that PMA is not only a clinical picture with a decrease in airway calibre that can be related to the regulation of 2 receptors, but also a complex state with worsening of airway inflammation.	12375711
Inflammation, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	Effect of suplatast tosilate on airway hyperresponsiveness and inflammation in asthma patients.	12375715
Airway structure, Inflammation, Asthma	Altered Intercellular Communication	Because eosinophilic airway inflammation is a characteristic of bronchial asthma, the treatment of such inflammation is important in the management of this disease.	12375715
Inflammation, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	These results strongly suggest that oral administration of suplatast tosilate suppresses airway hyperresponsiveness in asthma patients by reducing eosinophilic inflammation in the airways.	12375715
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Angina Pectoris, Cardiovascular Diseases	Altered Intercellular Communication	Markers of inflammation, such as C-reactive protein (CRP), were found to be related to risk for cardiovascular disease (CVD) events in patients with angina pectoris.	12375803
Atherosclerosis	Altered Intercellular Communication	In addition, recent studies have shown that, in the case of atherosclerosis, increased CRP concentration reflects the inflammatory condition of the vascular wall.	12375803
Autoimmune Diseases, Communicable Diseases, Inflammation	Altered Intercellular Communication	The predictive value of specific markers of infection and autoimmunity for coronary events, such as the effects of statins on inflammation, is still controversial.	12375804
Inflammation, Cardia of stomach, Esophageal injury	Altered Intercellular Communication	Endoscopy revealed inflammation of the oropharynx and second-degree caustic injury of the oesophagus extending to the cardia.	12376715
Tumor necrosis, Gastrointestinal inflammation, Crohn Disease	Altered Intercellular Communication	Tumour necrosis factor alpha (TNF-alpha) plays a key role in the pathogenesis of intestinal inflammation in Crohn's disease.	12377803
Communicable Diseases, Inflammation	Altered Intercellular Communication	One fifth of all false-positive PET scans occurred at sites of known inflammation or infection.	12377963
Inflammation, Lymphoma	Altered Intercellular Communication	Development of PAL is closely related to antecedent chronic inflammatory condition; therefore, PAL should be defined as malignant lymphoma developing in chronic inflammation.	12377970
Inflammation, Lymphoma	Altered Intercellular Communication	Development of PAL is closely related to antecedent chronic inflammatory condition; therefore, PAL should be defined as malignant lymphoma developing in chronic inflammation.	12377970
Radiology Specialty, Arthritis, Periarticular Route of Administration, Refractory anemias	Altered Intercellular Communication	Secondly, to determine whether periarticular bone loss is related to joint inflammation and radiological erosions in RA and PsA.	12379525
Refractory anemias, Arthritis, Periarticular osteoporosis	Altered Intercellular Communication	Among patients with RA, periarticular osteoporosis was related to measures of joint inflammation.	12379525
PROS1 gene, Inflammation, Arthritis, Periarticular Route of Administration	Altered Intercellular Communication	There was no association between joint inflammation and periarticular bone loss in patients with PsA, which lends support to the hypothesis that the primary site of inflammation in PsA is extrasynovial.	12379525
Inflammation, SLC25A20 gene, Atherosclerosis	Altered Intercellular Communication	Two factors that may be related to subsequent cardiovascular events are coronary calcium (CAC, a manifestation of subclinical atherosclerosis) and high-sensitivity C-reactive protein (CRP, a measure of chronic inflammation).	12379576
Sepsis, Inflammation	Altered Intercellular Communication	Infants with either BCG scarring (n = 10) or BCG lesional inflammation (n = 5) had no symptoms of sepsis, but 18 of 33 infants without BCG vaccination lesions did.	12379697
Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	Reciprocal SCr at baseline correlated with the percentage of normal glomeruli (r = 0.584, p = 0.005), crescent score (r = -0.595, p = 0.003), interstitial fibrosis as a percentage of cortical surface area (r = -0.669, p = 0.002), interstitial inflammation (r = -0.439, p = 0.041), eosinophil (r = -0.495, p = 0.019), neutrophil score (r = -0.557, p = 0.005), and acute sum score (r = -0.499, p = 0.018).	12381950
Inflammation, Neoplasms	Altered Intercellular Communication	In 13 patients the results were benign tumors or specific inflammation.	12382003
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	Hypoalbuminemia is multifactorial and related to poor nutrition, inflammation, and comorbid disease.	12382212
Inflammation, Failure (biologic function)	Altered Intercellular Communication	Individual postoperative complications significantly associated with increased risk of failure of trabeculectomy are elevated IOP (3.4, 1.9-6.1, P <.001) and marked inflammation (2.4, 1.3-4.6, P =.006).	12383805
Inflammation, Postoperative Complications, Failure (biologic function), Diabetes Mellitus	Altered Intercellular Communication	Trabeculectomy failure was associated with younger age, higher pre-intervention IOP, diabetes, and one or more postoperative complications, particularly elevated IOP and marked inflammation.	12383805
Inflammation, Pseudomonas oryzihabitans	Altered Intercellular Communication	Owing to the persistence of inflammation despite intraocular vancomycin injection, the lens implant and capsule were removed and culture of the latter revealed the bacterium P. oryzihabitans.	12383826
Inflammation, Uveitis, Humor, Disorder of vitreous body	Altered Intercellular Communication	To clarify possible involvement of adrenomedullin in the pathophysiology of inflammation of eyes, we measured immunoreactive-adrenomedullin concentrations in the aqueous humor and plasma obtained from 14 control subjects and 56 patients with uveitis or vitreoretinal disorders.	12383875
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	CD14+,CD16+ blood monocytes and joint inflammation in rheumatoid arthritis.	12384915
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	We undertook this study to investigate the relevance of this phenotype to joint inflammation in rheumatoid arthritis (RA).	12384915
Refractory anemias, Inflammation	Altered Intercellular Communication	These results indicate that the maturation of blood monocytes into tissue-infiltrative CD16+ cells before entry into the joint, induced by cytokine spillover from the inflamed joint, may contribute to the persistent joint inflammation of RA.	12384915
PROS1 gene, Arthritis	Altered Intercellular Communication	To investigate whether alefacept (a fully human lymphocyte function-associated antigen 3 [LFA-3]/IgG1 fusion protein that blocks the LFA-3/CD2 interaction) is able to reduce the signs and symptoms of joint inflammation in patients with active psoriatic arthritis (PsA).	12384938
Inflammation	Altered Intercellular Communication	Furthermore, since alefacept, a T cell-specific agent, led to decreased macrophage infiltration, the data indicate that T cells are highly involved in synovial inflammation in PsA.	12384938
Inflammation, Fibrosis Assessment, Liver Cirrhosis	Altered Intercellular Communication	In these cases, the sample of liver tissue does not reflect the true degree of inflammation, fibrosis, or cirrhosis, despite an adequate sample size.	12385448
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Inflammation and fibrosis were scored according to the standard grading (inflammation) and staging (fibrosis) method based on the modified Scheuer system.	12385448
Ischemia, Inflammation	Altered Intercellular Communication	Major complications were more likely in cases with major tissue disruption, ischaemia, or inflammation.	12386091
Inflammation, Venous Thrombosis, Hepatic Vein Thrombosis, Secondary malignant neoplasm of liver, Heart failure, Pericarditis, Constrictive, Liver Cirrhosis	Altered Intercellular Communication	THAD were associated to: Budd-Chiari syndrome (9), portal venous thrombosis (10), liver cirrhosis (7), acute inflammation of an adjacent organ (4), dilatation of the entire biliary tree (3), hepatic stasis caused by heart failure (2) and constrictive pericarditis (1), fine-needle percutaneous biopsy (2), arterioportal shunting (2), parenchymal compression by fractured ribs (2) and by a strengthened phrenic pillar (1).	12386553
Inflammation	Altered Intercellular Communication	The localised non-sectoral THAD (7), with variable morphology and without the clear border sign, were associated to acute inflammation of an adjacent organ (4) and to parenchymal compression by the ribs or diaphragm (3).	12386553
Inflammation, Traumatic injury	Altered Intercellular Communication	We recognise 4 causes: portal vein stoppage-obstruction, portal in-flow diversion, trauma and inflammation.	12386553
Inflammation, Hypoperfusion	Altered Intercellular Communication	In the fourth group the mediators of the arterial phenomena are those of inflammation even though portal hypoperfusion might be involved as well.	12386553
Inflammation, Hemorrhage, Blood Coagulation Disorders	Altered Intercellular Communication	No correlation was detected between C(ss) quartile and bleeding risk or the magnitudes of effect on biomarkers of coagulopathy (D-dimers and protein C) and inflammation (interleukin 6).	12386641
Inflammation, Swelling, Lymphoma, Neoplasms	Altered Intercellular Communication	Swelling in the lymph nodes leads one to think at first in terms of diagnostic differentials such as local inflammation, tumor metastases, or lymphomas.	12386797
Juvenile arthritis, Inflammation, Autoimmune Diseases, Refractory anemias, Rheumatoid Arthritis, Destruction (action), Juvenile rheumatoid arthritis	Altered Intercellular Communication	Juvenile idiopathic arthritis (JIA) is the most common childhood autoimmune rheumatic disease and like rheumatoid arthritis (RA), it is characterized by inflammation and the progressive destruction of joints.	12389647
Inflammation	Altered Intercellular Communication	Chronic inflammation was the most important histological factor that determined DNA damage.	12390206
Inflammation, immunoglobulin A, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Our results may indicate that C. pneumoniae contributes to increased inflammation in CHD, and that this contribution is even more pronounced when present in combination with H. pylori IgA antibodies.	12390284
Airway structure	Altered Intercellular Communication	Quantitations of exhaled nitric oxide (NO) and carbon monoxide (CO) have been proposed as noninvasive markers of airway inflammation.	12391056
Pneumonitis	Altered Intercellular Communication	We hypothesized that exhaled CO is increased in individuals with alpha(1)-antitrypsin (AT) deficiency, who have lung inflammation and injury related to oxidative and proteolytic processes.	12391056
Inflammation, Asthma	Altered Intercellular Communication	The association of sensitive systemic inflammation markers with bronchial asthma.	12392382
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation is a characteristic feature of bronchial asthma.	12392382
Inflammation, Asthma	Altered Intercellular Communication	To analyze the association of asthma with three sensitive markers of systemic inflammation, C-reactive protein, serum amyloid-A (SAA), and plasma fibrinogen.	12392382
Inflammation, Asthma	Altered Intercellular Communication	The odds ratios of asthma were analyzed by quartile of each inflammation marker.	12392382
Inflammation, Asthma	Altered Intercellular Communication	Sensitive markers of systemic inflammation, particularly SAA and fibrinogen, were positively and significantly associated with asthma prevalence.	12392382
Inflammation, Asthma	Altered Intercellular Communication	These findings support the hypothesis that not only local, but also systemic, inflammation exist in bronchial asthma.	12392382
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic Syndrome X, Atherosclerosis	Altered Intercellular Communication	Our study indicates that low-grade inflammation is correlated to IMT, as an indicator of early atherosclerosis, and is strongly associated to a variety of risk factors within the metabolic syndrome in a population at risk for type 2 diabetes.	12393098
Inflammation, Bothered by Vomiting, Fever, CTCAE	Altered Intercellular Communication	Otalgia, fever, poor feeding and vomiting were the most common symptoms, all the children had evidence of retroauricolar inflammation.	12393248
Hepatitis	Altered Intercellular Communication	C-1858 was associated with more liver inflammation.	12394372
Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain and neurologic symptoms may occur secondarily to concomitant illnesses instead of being caused by the inflammation itself.	12394939
Cyst, Inflammation, Fibrous	Altered Intercellular Communication	Histopathologic examination of each cyst showed a cyst wall of fibrous tissue with synovial lining, inflammation, and granulation tissue.	12394940
Amyotrophic Lateral Sclerosis	Altered Intercellular Communication	Disturbance of glutamate neurotransmission may contribute to the motor neuron injury seen in amyotrophic lateral sclerosis.	12395117
Inflammation, Lipoma	Altered Intercellular Communication	Magnetic resonance imaging (MRI) and excisional biopsy revealed fatty villi and synovial inflammation within the left bicipitoradial bursa, consistent with lipoma arborescens.	12395279
Hepatic Encephalopathy	Altered Intercellular Communication	Given that activation of sGC by NO in brain is involved in the modulation of important cerebral processes such as intercellular communication, learning and memory, and the sleep-wake cycle, these changes could be implicated in the pathogenesis of hepatic encephalopathy in these patients.	12395325
Vocal cord structure, Laryngitis, Hoarseness	Altered Intercellular Communication	Since the beginning of 1991, the senior authors (RTS, JRS) have recognized a clinical syndrome defined by prolonged hoarseness, prolonged laryngeal inflammation, and vocal fold ulceration.	12395997
Inflammatory abnormality of the eye, Fever, CTCAE, Headache	Altered Intercellular Communication	A 28-year-old woman with ocular inflammation, fever, and headache.	12397194
Bile Duct Stenosis, Leakage of bile, Pancreatitis	Altered Intercellular Communication	Bile duct stenosis due to surrounding pancreatic inflammation was demonstrated in two of the patients in which sphincterotomy failed to stop bile leakage.	12397716
Inflammation, Fibrosis Assessment, Malignant Neoplasms	Altered Intercellular Communication	The final pathology report in all patients showed marked fibrosis and inflammation of the biliary duct without evidence of malignancy.	12399056
Communicable Diseases, Inflammatory abnormality of the eye	Altered Intercellular Communication	These ophthalmological medical emergencies were classified as follows: 20% infections disease, 12.6% ocular inflammation, 0.8% neurophthalmology.	12399726
Angioedema, Lung Diseases, Obstructive, Inflammatory abnormality of the eye, Glomerulonephritis	Altered Intercellular Communication	Angioedema, ocular inflammation, obstructive lung disease, and glomerulonephritis are commonly associated with HUV.	12399749
Inflammation, Rheumatoid Arthritis, Anemia	Altered Intercellular Communication	[Effects of the chemokine MIP-1alpha on anemia and inflammation in rheumatoid arthritis].	12399885
Refractory anemias, Inflammation	Altered Intercellular Communication	The results show that enhanced expression of MIP-1alpha is indicative of systemic inflammation in RA.	12399885
palladium, Inflammation	Altered Intercellular Communication	All of those features suggest that plasma leptin levels could be considered a marker of CV risk and food intake in non obese PD patients without inflammation.	12402621
Inflammation, Peritonitis, Cancer-related fatigue, palladium, Hyperferritinaemia	Altered Intercellular Communication	Hyperferritinemia registered in CRF patients on PD with frequent peritonitis may be considered as a result of active ferritin synthesis by the cells of the system of mononuclear phagocytes in response to inflammation.	12402772
Inflammation, Cervix Diseases	Altered Intercellular Communication	The high rate of endocervical disease, inflammation and small lesions may explain the cytological difficulties leading to an 'inconclusive' result.	12403288
Inflammation, Chronic Obstructive Airway Disease, Tumor necrosis	Altered Intercellular Communication	Local and systemic inflammation in patients with chronic obstructive pulmonary disease: soluble tumor necrosis factor receptors are increased in sputum.	12403691
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by significant chronic inflammation in the pulmonary compartment as well as in the circulation.	12403691
ARCN1 gene, Inflammation	Altered Intercellular Communication	In addition, sputum sTNF receptors were inversely related to the FEV(1) in patients with COPD, whereas circulating sTNF receptors were not, suggesting different regulation of inflammation in the pulmonary and systemic compartment.	12403691
Airway structure, Neurogenic Inflammation, Asthma	Altered Intercellular Communication	In asthma, neurogenic inflammation in bronchial airways may occur though the release of neuropeptides from C fibers via an axon reflex.	12403698
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Endogenous or exogenous microparticles could aggravate the ongoing inflammation of inflammatory bowel disease.	12404229
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histopathologic examination revealed stratified squamous epithelium and soft tissue with substantial fibrosis and mild chronic inflammation, findings consistent with the characteristics of a remnant cast from a previous fistulous tract.	12404523
Inflammation, Sarcoidosis	Altered Intercellular Communication	These results suggest that the inflammation in sarcoidosis could be effectively and non-invasively determined by the analysis of cell differential counts and T-lymphocyte subsets in IS.	12405490
Inflammation, Respiratory Syncytial Virus Infections	Altered Intercellular Communication	Cysteinyl-leukotrienes (cys-LT) are released during RSV infection and may contribute to the inflammation.	12406832
Airway structure, Asthma	Altered Intercellular Communication	We conclude that exhaled cys-LTs and LTB4 may be noninvasive markers of airway inflammation in pediatric asthma.	12406853
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by inflammation of the respiratory tract in which macrophages are the predominant inflammatory cell and for which the efficacy of treatment with corticosteroids is controversial.	12406856
Inflammation, Atherosclerosis, HD Term Type, Infection, Amyloidosis	Altered Intercellular Communication	Oxidative stress and inflammation contribute to the high prevalence and severity of atherosclerosis, infections, and beta2-microglobulin amyloidosis; and thus, to reduced survival rate and quality of life in hemodialysis (HD) patients.	12407646
HD Term Type	Altered Intercellular Communication	Inflammation-induced lipid and protein oxidation and IVIR-induced lipid oxidation were shown in HD patients.	12407646
Finger joint structure, Inflammation	Altered Intercellular Communication	A 27-year-old male presented with the complaints of recurring attacks of painful inflammation affecting finger joints of both hands for last one year.	12408287
Inflammation, Dermatitis, Allergic Contact, Immediate hypersensitivity, Spanish Language, Ulcerative Colitis, Data types - Address, Spondylarthritis	Altered Intercellular Communication	In this report we have investigated possible relationships between IgE-mediated allergic disease (AD), allergic contact dermatitis (ACD) and seronegative spondyloarthropathy (SpA) in UC patients at different grades and extensions of mucosa inflammation.	12408520
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Definitive histologic diagnosis of ulcerative colitis relies upon mucosal architectural distortion and inflammation in the appropriate clinical setting.	12409720
Keratitis	Altered Intercellular Communication	To evaluate patients' self-assessment of their symptoms and cosmetic appearance after fluorescein-potentiated argon laser treatment (FPAL) for corneal inflammation associated with neovascularization.	12410033
Inflammatory disorder	Altered Intercellular Communication	The cell shape and the expression of Cx43 in 18 cases of NPC and 10 cases of chronic inflammation disease of nasopharyngeal epitheliems (CIDNE) were observed under the laser scanning confocal microscopy and technology of fluorescence.	12412425
Inflammation, Collagen Diseases	Altered Intercellular Communication	Increased levels of high sensitive C-reactive protein in patients with chronic rheumatic valve disease: evidence of ongoing inflammation.	12413502
Inflammation, Collagen Diseases	Altered Intercellular Communication	The aim of this study was to determine the role of inflammation detected by high sensitivity CRP (hs-CRP) levels in the progression of chronic rheumatic valve disease.	12413502
Inflammatory abnormality of the eye	Altered Intercellular Communication	This is the first report of ocular inflammation as the presenting finding in the recently recognized syndrome of immune-recovery MAC disease.	12414430
Inflammation, Pain, Postoperative	Altered Intercellular Communication	Relation of patient and surgical variables to postoperative pain and inflammation in the extraction of third molars.	12415220
Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain was scored on a visual analog scale (VAS) 0, 8, 24, 43 and 48 hours after surgery, while inflammation was rated by means of a verbal response scale (VRS) 48 hours after extraction.	12415220
Pain Distress Question, Inflammation	Altered Intercellular Communication	In turn, patients with increased intensity pain also present greater inflammation.	12415220
Refractory anemias, Inflammation	Altered Intercellular Communication	This report supports the hypothesis that chronic inflammation affects antioxidant vitamin levels in RA.	12415581
Pain Distress Question, Inflammation, Rheumatoid Factor, Leukocytosis	Altered Intercellular Communication	In an Austrian multicenter setting, patients were eligible if they had nontraumatic swelling or pain in at least one joint and laboratory signs of inflammation [elevated erythrocyte sedimentation rate, C-reactive protein, leukocytosis, or rheumatoid factor (RF)] within the last 3 months.	12415582
Refractory anemias, Arthritis	Altered Intercellular Communication	Our objective was to determine the contribution of HLA and cytokine gene polymorphisms implicated in RA to predisposition to PR and to progression of PR to chronic joint inflammation.	12415587
Arthritis	Altered Intercellular Communication	Time-adjusted survival analysis (Kaplan-Meier) and multivariate logistic regression were used to assess the independent contribution of immunogenetic markers in assessing progression of PR to chronic joint inflammation.	12415587
Inflammation, Neoplasms	Altered Intercellular Communication	The tumor uptake was high in sites of acute and active inflammation.	12416898
Inflammation, atherosclerotic	Altered Intercellular Communication	A new biomarker to reveal the presence of low grade subclinical smoldering inflammation in individuals with atherosclerotic risk factors.	12417286
Inflammation, atherosclerotic, Atherosclerosis	Altered Intercellular Communication	The association between increased erythrocyte adhesiveness/aggregation, higher concentrations of acute phase proteins, and increased atherosclerotic risk factors points to a possible clinical applicability of the erythrocyte adhesiveness/aggregation test (EAAT) to reveal the presence of both low-grade subclinical smoldering inflammation and morbid biology in individuals with risk factors for atherosclerosis.	12417286
Inflammation, Toxic effect	Altered Intercellular Communication	These results indicated that genes associated with the ubiquitin-proteasome system, oxidative toxicity, transcription, neuronal differentiation and inflammation might be involved in the pathogenesis of SALS.	12417341
Inflammation	Altered Intercellular Communication	Because cell-derived microparticles support coagulation and inflammation, they may be involved in atherogenesis.	12417540
Inflammation	Altered Intercellular Communication	Imosimase injection led to lysis of thick inflammation products, intensified sanation of focus.	12418318
Inflammation, Observation Method - Coagulation, Frailty	Altered Intercellular Communication	Frailty and activation of the inflammation and coagulation systems with and without clinical comorbidities: results from the Cardiovascular Health Study.	12418947
Inflammation, Diabetes Mellitus, Cardiovascular Diseases	Altered Intercellular Communication	These findings support the hypothesis that there is a specific physiological basis to the geriatric syndrome of frailty that is characterized in part by increased inflammation and elevated markers of blood clotting and that these physiological differences persist when those with diabetes and cardiovascular disease are excluded.	12418947
Inflammation, NCI CTEP SDC Liver and Hepatobiliary Cancer Sub-Category Terminology	Altered Intercellular Communication	The PCNA labeling index in the biliary epithelium in Helicobacter DNA-positive patients was statistically higher than that in Helicobacter DNA-negative ones, regardless of whether the patient was suffering from hepatobiliary cancer and/or biliary inflammation.	12419842
Inflammation	Altered Intercellular Communication	Nitric oxide (NO) plays a critical role in the regulation of vasodilation, neurotransmission, inflammation and many other events throughout the body.	12421162
Inflammation	Altered Intercellular Communication	Nitric oxide (NO) plays a critical role in the regulation of vasodilation, neurotransmission, inflammation and many other events throughout the body.	12421162
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Inflammation is an important phenomenon in atherosclerotic plaque growth and in plaque instability.	12422149
Acute Coronary Syndrome, Inflammation, Atherosclerosis	Altered Intercellular Communication	The pathogenesis of atherosclerosis and acute coronary syndromes involves inflammation and immunological mechanisms.	12423320
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Soluble leptin receptors and serum leptin in end-stage renal disease: relationship with inflammation and body composition.	12423321
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Apart from the decreased glomerular filtration rate (GFR), body composition and inflammation may affect leptin levels in ESRD.	12423321
Hepatic inflammation, Cholestasis, Jaundice, Obstructive	Altered Intercellular Communication	The excretion of biliary cysteinyl LTs increases with the severity of cholestasis and hepatic inflammation in patients with obstructive jaundice.	12424566
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Macrovesicular steatosis (MaS), fibrosis, and inflammation have been associated with poor graft function after liver transplantation.	12424718
Inflammation, Fibrosis Assessment, Microvesicular steatosis (disorder)	Altered Intercellular Communication	Percentages of MaS and microvesicular steatosis (MiS) were determined, and inflammation and fibrosis were scored as 0 to 4.	12424718
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	MaS correlated positively with MiS, and inflammation correlated positively with fibrosis, whereas patient weight showed a significant correlation with liver weight and body mass index.	12424718
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	When any site was compared with the average of the other sites, Spearman's rho correlation ranged from 0.89 to 0.95 for MaS, 0.89 to 0.94 for MiS, 0.54 to 0.80 for inflammation, and 0.66 to 0.80 for fibrosis.	12424718
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Two biopsies explained 95% of variations for MaS and MiS and 85% for inflammation and fibrosis.	12424718
Airway structure, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Differences in airway inflammation in patients with fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease.	12426229
allergic inflammation	Altered Intercellular Communication	Glucocorticoids are effective drugs for treating allergic inflammation.	12426281
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	In vitro and in vivo data suggest that markers of inflammation and nutritional status may be risk factors for the progression of chronic kidney disease.	12427147
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Multicentric inflammation in epicardial coronary arteries of patients dying of acute myocardial infarction.	12427409
Inflammation, Retroperitoneal Space, Malignant Neoplasms	Altered Intercellular Communication	Its etiology includes several medications, periaortic inflammation, abdominal and retroperitoneal operations, radiotherapy, and malignancy.	12429295
Inflammation, Osteoporosis, Refractory anemias, Immobile, Rheumatoid Arthritis	Altered Intercellular Communication	Preliminary clinical criteria based on age, inflammation, and immobility have been proposed to identify which patients with rheumatoid arthritis (RA) should be examined by dual energy x ray absorptiometry (DXA) to diagnose osteoporosis.	12429540
Sarcoidosis, Vasculitis, CTCAE, Chronic inflammatory disorder, "Sjogrens Syndrome", Behcet Syndrome, MS gene, Lupus Erythematosus	Altered Intercellular Communication	The high prevalence of anti-proteasome autoantibodies in multiple sclerosis sera compared with sera from patients with other chronic inflammatory conditions: systemic lupus erythematosus (35%, 35 out of 100), primary Sjogren's syndrome (16%, 5 out of 31), vasculitis (0 out of 20), sarcoidosis (7%, 1 out of 13) and Behcet's disease (19%, 4 out of 21) suggest that humoral autoreactivity to proteasome could be a useful test in multiple sclerosis patients that may be of help in the diagnosis and/or progression of this chronic inflammatory disease.	12429593
Inflammation, Fibrosis Assessment, Lung diseases	Altered Intercellular Communication	Chest radiographs and pulmonary function tests show interstitial and restrictive lung disease, while the histologic appearance is that of a centrilobular inflammatory process with small airway fibrosis and inflammation that radiates into the interstitium of the distal acinus in a patchy fashion.	12429793
Inflammation, Necrosis, Neoplasms, Fibrosis	Altered Intercellular Communication	All tumors showed circumscribed growth, a tubular growth pattern with focal solid areas, no significant nuclear atypia and absence of necrosis, desmoplasia, or inflammation.	12429795
Pain Distress Question	Altered Intercellular Communication	Oral non-steroid anti-inflammation analgesics and milder opioids (codeine and tramadol) failed to relieve the pain.	12434612
Diarrhea, Dysentery	Altered Intercellular Communication	Fecal leukocytes are found in diarrhea patients with diffuse colonic inflammation but missing in non-inflammatory cases, and are most commonly identified in infectious diarrheas of bacterial origin.	12434630
ARCN1 gene, Inflammation	Altered Intercellular Communication	This probability was unrelated to the presence of COPD or to signs of epithelial inflammation.	12435317
Inflammation	Altered Intercellular Communication	Restenotic lesions from QuaDS-QP2-eluting stents at 12 months show persistent fibrin deposition with varying degrees of inflammation.	12438288
Inflammation	Altered Intercellular Communication	The nonreabsorbable polymer alone may have induced chronic inflammation.	12438288
Inflammation, Malignant Fibrous Histiocytoma, Neoplasms	Altered Intercellular Communication	Against the background of dense inflammation, inflammatory malignant fibrous histiocytoma was first diagnosed, but typical morphologic features in the recurrent tumor led to a correction of the diagnosis--inflammatory myxohyaline tumor.	12440787
Inflammation, Fibrosis Assessment, Hypoxemia	Altered Intercellular Communication	This case demonstrates that the severe inflammation, not the fibrosis, of the lungs plays a major role in the lethal hypoxemia of patients with paraquat poisoning during the subacute period and confirms our previous hypotheses.	12441774
Inflammation, Compression, Cellulitis	Altered Intercellular Communication	Sometimes, when the inflammation is severe, an infectious cellulitis or muscular compression may be suspected.	12442101
Inflammation, Fever, CTCAE	Altered Intercellular Communication	A 21-year-old woman was referred for the rapid occurrence of a diffuse and painful inflammation of the right leg, with fever.	12442101
Inflammation, Cellulitis	Altered Intercellular Communication	Abnormalities of the subcutaneous fat are similar to those of acute cellulitis, expressing the inflammation process secondary to the ecchymoses.	12442101
Inflammation, cinobufotalin, Bronchitis	Altered Intercellular Communication	15-lipoxygenase (15-LO) has been implicated in the inflammation of chronic bronchitis (CB), but it is unclear which of its isoforms, 15-LOa or 15-LOb, is primarily involved.	12444026
Cholecystitis	Altered Intercellular Communication	Conversion to open operation for severe gallbladder inflammation was necessary in 6 per cent of patients.	12445074
Inflammation	Altered Intercellular Communication	Gingival inflammation is characterized by infiltration of inflammatory mononuclear cells.	12445801
Inflammation, Acute Coronary Syndrome, Atherosclerosis	Altered Intercellular Communication	Inflammation has been shown to play a role in atherosclerosis and acute coronary syndromes.	12446059
Cataract, Acute inflammation	Altered Intercellular Communication	Dexamethasone and diclofenac were equally effective in reducing postoperative inflammation after phacoemulsification and IOL implantation in eyes with no other disease than cataract.	12446370
Hypophysitis, CTCAE, Inflammation, Hypopituitarism	Altered Intercellular Communication	This suggests that there may be at least two causative mechanisms for hypopituitarism in hypophysitis: nonspecific destruction of all types of adenohypophysial cells by severe inflammation and selective destruction of specific adenohypophysial cells.	12446917
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	The case is discussed in view of the inflammation hypothesis regarding Alzheimer's disease and the role of the apolipoprotein E4 genotype of the patient.	12446932
Inflammation, Neoplasms	Altered Intercellular Communication	In one patient, histopathologic assessment of the resected tumor revealed extensive coagulation necrosis with inflammation up to 10 mm in depth surrounding the bile duct lumen.	12447312
Inflammation	Altered Intercellular Communication	Therefore, CRP and ESR reflect systemic inflammation; however, plasma MMP-3 and the MMP-3/TIMP-1 ratio may reflect inflammation and/or degeneration of the affected joint.	12447632
intrauterine infection	Altered Intercellular Communication	Furthermore, multiple old and florid occlusions of fetal vessels had been detected together with focal lymphoplasmocytic inflammation, which may indicate that intrauterine infection and vascular compromise were the cause of the complete closure of the portal vein around birth.	12447666
Inflammation, Necrosis, Insemination, Artificial, Homologous	Altered Intercellular Communication	Review of the biopsy showed panlobular inflammation and bridging necrosis consistent with severe AIH.	12447711
Irritation - emotion, Corneal Endothelial Cell Loss, Chronic iridocyclitis	Altered Intercellular Communication	The thickness of the lens theoretically could also cause endothelial cell damage and mechanical iris irritation resulting in chronic uveal inflammation.	12449223
Inflammation, Rheumatic Fever	Altered Intercellular Communication	In contrast to high level of LPO processes induces diseases combined with inflammation, for instance rheumatic arthritis.	12450769
Airway structure, Asthma	Altered Intercellular Communication	High levels of serum eosinophil cationic protein (sECP) as a marker of eosinophilic airway inflammation have been described as a predictor of childhood asthma.	12452209
Inflammation, Wheezing	Altered Intercellular Communication	We investigated the possible correlation between eosinophilic inflammation and BHR in 72 infants with recurrent wheezing.	12452209
Inflammation, infection due to cardiac pacemaker, Postoperative hematoma	Altered Intercellular Communication	The most frequently encountered factors contributing to development of pacemaker infection were local complications such as postoperative hematoma and inflammation, and recurrent surgical interventions on the pacemaker system.	12452305
Inflammation, Cardia of stomach	Altered Intercellular Communication	Inflammation, however, appeared to be limited to the gastric cardia.	12453287
Narcolepsy, Sleep Disorders	Altered Intercellular Communication	Narcolepsy is a sleep disorder caused by impaired hypocretin (orexin) neurotransmission.	12453828
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	Recently, inflammation has received considerable attention in the pathogenesis of both type 2 diabetes and atherosclerosis.	12453918
HD Term Type, Inflammation, Anemia, Pruritus	Altered Intercellular Communication	We studied 68 HD patients to assess the role of iron deficiency, anaemia, inflammation and other common serum and dialysis parameters in pruritus.	12454228
Inflammation, Anemia, Pruritus	Altered Intercellular Communication	Iron deficiency and anaemia seem to play no part in HD-related pruritus, whereas lower serum transferrin and albumin levels and higher ferritin values are consistent with the possible role of inflammation in the development and severity of pruritus.	12454228
Tissue damage, Choline Dehydrogenase, Mitochondrial, Diabetes Mellitus	Altered Intercellular Communication	This finding provides a possible mechanism for tissue damage in chronic inflammatory conditions, including CHD and diabetes.	12454321
Inflammation, Fatty degeneration, Fatty Liver Disease	Altered Intercellular Communication	In the NASH group, native livers had focal steatosis, Mallory's hyalin, glycogenated hepatocytic nuclei, high-grade inflammation, and 3+ bile duct proliferation.	12454814
Gastritis, Atrophic	Altered Intercellular Communication	To determine which factors influence mucosal IL-1beta levels, gastric inflammation, and atrophy, multiple regression analyses were performed.	12454835
selenium, Gastritis, Atrophic	Altered Intercellular Communication	The 1/2 carriers were closely related to atrophy (PRC +/- SE; 0.87 +/- 0.4 [antrum] and 0.93 +/- 0.4 [corpus], P < 0.05), whereas being a carrier of the -511T/T genotype was related to severe gastric inflammation.	12454835
Carcinogenesis, Gastritis, Atrophic	Altered Intercellular Communication	IL-1 genetic polymorphisms influenced H. pylori-related gastric mucosal IL-1beta levels and were related to gastric inflammation and atrophy, factors thought to be important in gastric carcinogenesis.	12454835
malignant disease	Altered Intercellular Communication	The patients included those with inflammatory conditions of the colon as well as malignant disease.	12455799
Nasal inflammation, Rhinitis	Altered Intercellular Communication	Although rhinitis is extremely frequent in children, methods for assessing the severity of nasal inflammation produce results with wide variability and hence weak clinical significance.	12456911
Inflammation, Intussusception, Traumatic injury	Altered Intercellular Communication	Histologically, the presence of fibromuscular obliteration of the lamina propria with disorientation of muscle fibers is characteristic, which could be secondary to chronic mechanical and ischemic trauma and inflammation by hard stools, and intussusception of the rectal mucosa.	12456946
Inflammation, Neoplasms	Altered Intercellular Communication	To report the case of a 42-year-old patient referred for exploration of a tumor of the right flank and evidence of inflammation.	12457142
Intraocular inflammation, Uveitis	Altered Intercellular Communication	The evaluation and the management of IOP are very important in the treatment of patients with uveitis, in addition to the management of intraocular inflammation.	12457916
Inflammatory abnormality of the eye	Altered Intercellular Communication	The left eye showed no signs of ocular inflammation.	12457922
Inflammation, Neoplasms	Altered Intercellular Communication	According to the odds ratio (OR) values, CDKN2A-associated cases seemed to have tumours more often located on the head and neck (adjOR 2.9, 95% CI 0.6-13.7), with less inflammation (adjOR 0.7, 95% CI 0.3-1.8) and regression (adjOR 0.6, 95% CI 0.2-1.8) but more frequent histological ulceration (adjOR 1.9, 95% CI 0.6-5.8).	12459644
Inflammation, Weight decreased, Anorexia	Altered Intercellular Communication	In rodents, administration of TNF-alpha has been shown to stimulate plasma leptin concentration, suggesting that a cytokine-leptin link may mediate anorexia and weight loss during chronic inflammation.	12460331
Inflammation, Acute Coronary Syndrome, Atherosclerotic lesion	Altered Intercellular Communication	Neutrophils in unstable atherosclerotic lesions have not received much consideration, despite accumulating evidence suggesting a link between systemic inflammation and acute coronary syndromes.	12460868
Noninfiltrating Intraductal Carcinoma, Inflammation, Necrosis	Altered Intercellular Communication	The presence of stromal TSP-1 was significantly associated with DCIS showing no/little necrosis (p = 0.01) and no/little periductal inflammation (p = 0.04).	12461058
Inflammation, Necrosis	Altered Intercellular Communication	An increased stromal microvessel count was associated with high histological grade (p = 0.02), extensive necrosis (p = 0.047), and pronounced periductal inflammation (p = 0.049).	12461058
Uveomeningoencephalitic Syndrome, Behcet Syndrome, Intraocular inflammation	Altered Intercellular Communication	Behcet's disease and Vogt-Koyanagi-Harada (VKH) syndrome are characterized by a severe intraocular inflammation with a long course and recurrent episodes.	12461703
Inflammation	Altered Intercellular Communication	These lymphocytes may also be involved in the perpetuation and recurrence of this inflammation if they do not properly go into apoptosis.	12461703
Intraocular inflammation	Altered Intercellular Communication	These apoptosis-resistant, or long-lived, lymphocytes may be involved in the chronic and recurrent intraocular inflammation seen in these patients.	12461703
Inflammation, Injury of liver	Altered Intercellular Communication	IL-18 and IL-18BP correlated with laboratory parameters of inflammation and liver injury.	12462332
Aneurysm, Inflammation	Altered Intercellular Communication	Such aneurysms are caused by technical surgical failures, or inflammation of the sternum and mediastinum following sternotomy observed as an early or mid-term complication of cardiac surgery.	12463631
Virus Diseases, allergic inflammation, Autoimmune Chronic Hepatitis	Altered Intercellular Communication	Our patien's history is in agreement with the recently postulated pathomechanism of autoimmune hepatitis, according to which viral infections may trigger the disease in a genetically predisposed individuals persistently exposed to a constant antigenic stimulus, which results in ongoing allergic inflammation and finally develops into an immune process.	12464166
Granulomatous inflammation	Altered Intercellular Communication	The diagnosis is confirmed by identification of granulomatous inflammation and acid-fast bacilli.	12464853
Airway structure, Asthma	Altered Intercellular Communication	Induced sputum is a reproducible method to assess airway inflammation in asthma.	12467521
Airway structure, Asthma	Altered Intercellular Communication	We conclude that analysis of induced sputum is a reproducible method to study airway inflammation in asthma.	12467521
Juvenile arthritis, Inflammation	Altered Intercellular Communication	Clinical inflammation was less common in systemic-onset JIA.	12468825
Pain Distress Question, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Function, coping strategies, pain self-efficacy, inflammation and previous depression could predict 39.6% of the variance in pain.	12468828
Inflammation	Altered Intercellular Communication	The results suggested that these neuropeptides and cytokines might promote inflammation and stimulate proliferation and matrix synthesis of fibroblasts, contributing to the pathology of tennis elbow.	12469081
Inflammation, septic	Altered Intercellular Communication	Colon resection and immediate anastomosis are the first choice operation also in the emergency setting, provided local conditions (inflammation, septic contamination) make anastomosis safe.	12469467
Inflammation	Altered Intercellular Communication	Matrix metalloproteinases (MMPs) are a family of zinc-dependent endoproteinases that play an important role in inflammation and tissue degradation.	12471459
Communicable Diseases, Inflammation, Cryptococcus, HIV-1	Altered Intercellular Communication	Five of 10 patients who commenced successful highly active antiretroviral therapy (HAART) for infection with human immunodeficiency virus type 1 (HIV-1) concurrent with or soon after a diagnosis of cryptococcal infection experienced clinical events characterized by sterile inflammation.	12471589
Inflammation, Postoperative Complications, Tuberculosis, Pulmonary, Pain Distress Question	Altered Intercellular Communication	Although intense inflammation was observed as an immediate postoperative complication, fibrin, eye pain and phthisis did not develop in any of the patients.	12472167
Inflammation, Synovitis	Altered Intercellular Communication	The mRNA expression levels of interleukin-1beta (IL-1beta) and interleukin-1 receptor antagonists produced in the synovitis reflect the magnitude of inflammation.	12472254
Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	The areas of recurrence were associated with reflux symptoms and inflammation, with ulceration in two cases.	12472472
Inflammation	Altered Intercellular Communication	It also is an acute phase protein (APP) and its plasma concentration increases with inflammation.	12472798
Granulomatous inflammation	Altered Intercellular Communication	Histopathologic examination revealed granulomatous inflammation with failed microscopic detection of acid-fast bacilli using Ziehl-Neelsen stain.	12473896
Delirium, Chronic pain syndrome, Pulpitis	Altered Intercellular Communication	The authors recommend that the acute pain syndrome would be called the inflammation of upper tooth plexus, and the chronic pain syndrome--plexopathia of upper tooth.	12474698
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	The number of swollen joints, the mean of erythrocyte sedimentation rate (ESR) and rheumatoid factor (as indicators of inflammation) are correlated significantly with BMD of the hip.	12474739
Cataract, Inflammation, Lens Subluxation	Altered Intercellular Communication	Associated findings included neovascularization of the iris in one case (4%), shallow anterior chamber in 11 (48%), anterior chamber inflammation in five (22%), cataract in nine (39%), lens indentation in eight (35%), and lens subluxation in three (13%).	12476094
Inflammation, Erysipelas	Altered Intercellular Communication	After antibiotics treatment was initiated, inflammation of the erysipelas began to improve.	12476594
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	IL-6 and its soluble receptor (IL-6R) appeared as reliable markers of inflammation activity in autoimmune diseases.	12476893
Lichen Planus, Inflammation	Altered Intercellular Communication	The rationale for using tazarotene in oral lichen planus (OLP) is its regulatory action on the growth and differentiation of keratinocytes and on inflammation.	12477060
Shock, Inflammation, Multiple Organ Failure	Altered Intercellular Communication	All the patients had inflammation of soft tissue in the lower extremities, and developed shock and multiple organ failure immediately after the clinical visit.	12477090
Inflammation, Phlegmon, Fasciitis, Myositis, CTCAE 5.0	Altered Intercellular Communication	The inflammation of soft tissue was necrotising fasciitis in one case, myositis in one case, and phlegmon in one.	12477090
Inflammation, septic	Altered Intercellular Communication	The nature of the organism and its location to a joint are unusual features of this case, which illustrates the need to search for a septic complication before accepting a diagnosis of inflammation related to hyaluronate injection.	12477236
Inflammation, Vegetation	Altered Intercellular Communication	In 5/6 patients there were signs of inflammation, and in these patients IL-8- and TNF-alpha-containing cells were visualized in the heart valve stromas or vegetations.	12477328
Tumor necrosis, Inflammation, Traumatic injury	Altered Intercellular Communication	The proinflammatory cytokines interleukin-1beta (IL-1beta), interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-alpha) hold important functions in the early and late courses of inflammation, trauma and wound healing.	12477628
Inflammation, Bacterial Infections	Altered Intercellular Communication	A simple capillary leukocyte adhesiveness/aggregation test (CAPLAAT) might be helpful in determining the intensity of inflammation in acute viral and bacterial infections.	12478327
Pyelonephritis, Pyloric Stenosis, Nephritis, Phimosis	Altered Intercellular Communication	Outflow obstruction secondary to the phimosis appears to have caused pyelonephritis, and renal inflammation decreased responsiveness to aldosterone transiently.	12478361
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Inflammation plays an important role in the pathogenesis of acute coronary syndromes.	12478817
Inflammation, Carcinoma of lung	Altered Intercellular Communication	The positive rate of telomerase activity in 56 biopsy samples of lung cancer group was significantly higher than that in inflammation group (P < 0.001).	12479104
Inflammation, Oak preparation, Obesity	Altered Intercellular Communication	C-RP, as a measure of an acute phase response and inflammation, is highly associated with OAK; however, its high correlation with obesity limits its utility as an exclusive marker for OAK.	12479380
Airway structure, Asthma	Altered Intercellular Communication	Treatment decisions in asthma are based on assessments of symptoms and simple measures of lung function, which do not relate closely to underlying eosinophilic airway inflammation.	12480423
Inflammation, Exacerbation of asthma	Altered Intercellular Communication	We aimed to assess whether a management strategy that minimises eosinophilic inflammation reduces asthma exacerbations compared with a standard management strategy.	12480423
Inflammation, Exacerbation	Altered Intercellular Communication	The primary outcomes were the number of severe exacerbations and control of eosinophilic inflammation, measured by induced sputum eosinophil count.	12480423
Inflammation, Endothelial dysfunction, Platelet aggregation test result	Altered Intercellular Communication	Excessive amounts of n-6 PUFA or deficiency of n-3 PUFA may cause chronic inflammation, platelet aggregation, or endothelial dysfunction of microvasculature.	12480746
Inflammation, Atherosclerosis	Altered Intercellular Communication	Recent studies confirm that inflammation plays an important role in the development of atherosclerosis.	12480967
Inflammation, Hyperhomocysteinemia	Altered Intercellular Communication	The patients had slight hyperhomocysteinaemia (25.8 +/- 7.82 micromol/l), evidence of inflammation (CRP 5.16 mg/l (0.35-88.7)) and oxidative stress (oxLDL antibodies = 162 +/- 77 optical density at 495 nm x 1000).	12480967
Inflammation, Hyperhomocysteinemia	Altered Intercellular Communication	These results suggest that lipid peroxidation and inflammation, but not hyperhomocysteinaemia, are the main risk factors for mortality in haemodialysis patients receiving vitamin supplements.	12480967
Inflammation, Atherosclerosis	Altered Intercellular Communication	Carotid atherosclerosis is associated with inflammation and endothelial cell adhesion molecules in chronic haemodialysis patients.	12480968
HD Term Type, Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	In HD patients, carotid atherosclerosis is associated with inflammation and circulating levels of soluble adhesion molecules ICAM-1 and VCAM-1.	12480968
Inflammation	Altered Intercellular Communication	Waldeyer's throat ring revealed signs of acute inflammation.	12481238
Hypertension, CTCAE	Altered Intercellular Communication	Blood pressure increase and incidence of hypertension in relation to inflammation-sensitive plasma proteins.	12482834
Cardiovascular Diseases	Altered Intercellular Communication	The reasons for the relationship between inflammation-sensitive plasma proteins (ISPs) and incidence of cardiovascular diseases are poorly understood.	12482834
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Interleukin (IL)-6-mediated inflammation is involved in cardiovascular disease (CVD).	12482836
Infarction, Inflammation, Atherosclerosis	Altered Intercellular Communication	Although the -174C allele was not associated with incident events, associations of the genotype with inflammation and MRI infarcts, combined with the plasma IL-6 results, suggest that IL-6 may chronically predispose an individual to develop atherosclerosis.	12482836
Inflammation, Blood Clot, Vascular Diseases, Avascular necrosis of bone	Altered Intercellular Communication	Skin biopsy specimens of both vesicle and pustule revealed fibrin thrombi deposition in the small dermal vessels with little inflammation, subepidermal bulla, and ischemic necrosis of the overlying epidermis, which were consistent with a vasculopathic reaction.	12483016
Inflammation, Neoplasm Metastasis, Neoplasms, Intrahepatic bile duct, Lymphadenopathy, Frontotemporal degeneration	Altered Intercellular Communication	CT scans were analyzed for the following parameters: tumor (detection, location, gross morphologic type, contrast enhancement), intrahepatic bile duct (dilatation, pattern of dilatation), common bile duct (dilatation, Clonorchis sinensis worms), gallbladder (inflammation, C. sinensis worms), invasion of the contiguous viscera (pancreas, duodenum, liver), lobar atrophy, and lymphadenopathy and metastasis.	12483388
Inflammation, Atrophic	Altered Intercellular Communication	The following histopathologic changes were observed: (1) cystic dilatation of acini and/or ducts, (2) atrophy of acini, (3) basement membrane thickening of acini, (4) granulation tissue, and (5) lipogranulomatous inflammation.	12484702
Inflammation, Atrophic	Altered Intercellular Communication	Biopsies of the gastric mucosa from a population of dyspeptic patients were graded for level of chronic inflammation, neutrophil activity, atrophy, and H. pylori density.	12485119
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The periportal and/or intralobular inflammation and fibrosis were G1 and S1.	12485527
Data types - Address	Altered Intercellular Communication	Stimulation of G proteins and coupled signaling by GSH antioxidant analogues, as potential signaling molecules, may ameliorate the oxidative impairments of neuronal signaling in AD.	12485924
Seizures, Epilepsy, Generalized	Altered Intercellular Communication	Increased gamma EEG is probably a marker of the underlying ion channel or neurotransmitter receptor dysfunction in primary generalised epilepsies and may also be a pathophysiological prerequisite for the development of seizures.	12486266
Conjunctivitis	Altered Intercellular Communication	Efficacy of indomethacin 0.1% and fluorometholone 0.1% on conjunctival inflammation following chronic application of antiglaucomatous drugs.	12486516
Conjunctivitis	Altered Intercellular Communication	Conjunctival inflammation was assessed under masked conditions by means of conjunctival impression analysis which determined the percentage of cells expressing HLA-DR.	12486516
Conjunctivitis	Altered Intercellular Communication	Both anti-inflammatory eyedrops were effective in reducing subclinical conjunctival inflammation before filtering surgery.	12486516
Inflammation	Altered Intercellular Communication	All above mentioned results may have as a common denominator an improved blood purification from uremic toxins and a reduced level of chronic sub-clinical inflammation.	12487392
Inflammation, Complication Aspects, Myositis, CTCAE 5.0, Scleritis	Altered Intercellular Communication	During an attack ocular complications were more common in patients with scleritis and myositis (64%) than in patients with scleritis alone (30.4%), indicating a more diffuse and potentially dangerous inflammation.	12488260
Inflammation, Malnutrition	Altered Intercellular Communication	In this study the influence of malnutrition and inflammation on acute haematological toxicity was investigated.	12488290
Inflammation, Necrosis	Altered Intercellular Communication	The MRI grade of hepatic siderotic nodules correlated significantly with the grade of periportal inflammation (r = 0.301, P < 0.05) but not with the grade of piecemeal necrosis.	12488748
Inflammation, Necrosis	Altered Intercellular Communication	The grade of parenchymal iron deposition was not correlated with the grade of periportal inflammation or piecemeal necrosis.	12488748
Inflammation, Necrosis	Altered Intercellular Communication	There was a nonsignificant trend toward correlation between the histologic grade of hepatic iron content and the grades of periportal inflammation and piecemeal necrosis.	12488748
Gingivitis, Dental caries, Enamel defect, Gingival Hyperplasia, Dental Plaque	Altered Intercellular Communication	Indices were recorded for dental caries, dental plaque, gingival inflammation, gingival enlargement, and enamel defects.	12488989
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Oxidative stress and inflammation have recently been implicated in endothelial dysfunction.	12489494
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Our study shows that PMNL in smokers are primed in vivo, contribution concomitantly to systemic oxidative stress and inflammation that predispose smokers to endothelial dysfunction, and explains in part the accelerated atherosclerosis found in smokers.	12489494
allergic inflammation, Allergic fungal sinusitis, TBX1 wt Allele	Altered Intercellular Communication	Allergic fungal sinusitis (AFS) is considered an allergic inflammation against fungus, and has been reported to be refractory, with very high recurrence.	12491597
Inflammation, Urinary tract infection	Altered Intercellular Communication	Our case was more difficult to diagnose because she showed few signs of inflammation and had no history of urinary tract infection or stones.	12491617
Neurogenic Inflammation	Altered Intercellular Communication	Of them 35 patients with urogenital inflammation were treated by transperineal seminal vesicle puncture under ultrasound guidance and continuous transcatheter antibiotic drugs instillation.	12491695
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	However, UMH excretion correlated strongly with endoscopic severity of inflammation in Crohn's disease (Crohn's Disease Endoscopic Index of Severity r2 = 0.70, p < 0.0001) or disease extent in ulcerative colitis.	12492192
Refractory anemias, Inflammation	Altered Intercellular Communication	The results confirm calprotectin as a good measure of disease activity and joint inflammation in RA.	12492250
Edematous skin, Inflammation	Altered Intercellular Communication	PEH was associated with increased epidermal thickness, less dermal edema, more dermal inflammation, fresh fibrin, and red blood cell extravasation.	12496699
Cyst of biliary tract, Inflammation, Squamous cell carcinoma	Altered Intercellular Communication	Squamous carcinoma might develop in a context of inflammation as in biliary cyst.	12498226
Inflammation	Altered Intercellular Communication	This may be due to saturation of enzymes in ALC and ongoing inflammation in VIC.	12498283
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	A growing body of evidence suggests that Alzheimer's disease (AD) is associated with local inflammation processes.	12499050
Coma (genus), Neoplasms	Altered Intercellular Communication	One patient presented with coma due to inappropriate secretion of antidiuretic hormone associated with a stage B tumour.	12499774
Kidney Failure, Chronic, Inflammation, Calcification of coronary artery	Altered Intercellular Communication	An association between coronary artery calcification score, lipid profile, and selected markers of chronic inflammation in ESRD patients treated with peritoneal dialysis.	12500238
Inflammation, SLC25A20 gene	Altered Intercellular Communication	Our results may suggest an association between CAC and chronic inflammation activity in the mentioned group of patients.	12500238
Inflammation, Neoplasm Metastasis, Tuberculosis, Sarcoidosis, Hypertrophy, Hyperplasia	Altered Intercellular Communication	The enlargement occurred due to nonspecific inflammation (38.6%), common hyperplasia (26.3%), tuberculosis (18.5%), metastases of cancer (14.9%), sarcoidosis (1.7%).	12501770
Pharyngitis, Acid reflux	Altered Intercellular Communication	[Relationship of pathological gastroesophageal reflux and some symptoms of chronic laryngeal and pharyngeal inflammation].	12501775
Pharyngitis	Altered Intercellular Communication	It is proposed to conduct a gastroenterological examination of patients with persistent chronic inflammation of laryngeal and pharyngeal mucosa.	12501775
Inflammation, Periodontal Diseases	Altered Intercellular Communication	Further: an improvement in the gingival inflammation caused by a periodontal disease was observed, and periodontal pocket depth was maintained.	12502130
Inflammation, Acute Cholecystitis	Altered Intercellular Communication	Although unclear anatomy secondary to inflammation remains the most common reason for conversion, the impact of acute cholecystitis on the operative outcome has decreased with time.	12504217
Inflammation, Malnutrition	Altered Intercellular Communication	However, malnutrition is the reflect of general condition, and the respective roles of malnutrition and inflammation have not yet been clearly established.	12504235
Inflammation, Hypocholesterolemia	Altered Intercellular Communication	The results confirm an association between nutritional status and hypocholesterolemia, and suggest also the responsability of inflammation as a cause of hypocholesterolemia.	12504235
Inflammation	Altered Intercellular Communication	Histiocytic inflammation was more common in patients with clinical symptoms (p<0.001) and around subglandular implants (p<0.096).	12504533
Inflammation, Venous Thromboembolism, Thromboembolism	Altered Intercellular Communication	Coagulation factors, inflammation markers, and venous thromboembolism: the longitudinal investigation of thromboembolism etiology (LITE).	12505113
Tubular atrophy, Interstitial Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	Monocyte chemoattractant protein-1 (MCP-1), is a chemokine that mediates renal interstitial inflammation, tubular atrophy, and interstitial fibrosis by recruiting monocytes/macrophages into renal tubulointerstitium.	12505750
Cerebral Arterial Diseases	Altered Intercellular Communication	Tissue specimens obtained in 22 cases of other cerebral diseases, among which were various inflammatory conditions.	12507138
EPHA7 gene, Inflammation	Altered Intercellular Communication	Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation.	12508119
Inflammatory Bowel Diseases, Inflammation, Sepsis, Rheumatoid Arthritis, Endotoxemia, Disease	Altered Intercellular Communication	Excessive inflammation and tumour-necrosis factor (TNF) synthesis cause morbidity and mortality in diverse human diseases including endotoxaemia, sepsis, rheumatoid arthritis and inflammatory bowel disease.	12508119
Inflammation	Altered Intercellular Communication	Highly conserved, endogenous mechanisms normally regulate the magnitude of innate immune responses and prevent excessive inflammation.	12508119
Giant Cell Arteritis, Granulomatous inflammation, GCA gene	Altered Intercellular Communication	Giant cell arteritis (GCA) is a disease of unknown etiology characterized by granulomatous inflammation of medium and large arteries.	12508411
Inflammation	Altered Intercellular Communication	Polymorphism of phagocyte IgG receptor Fc gamma RIIa may modulate immune complex mediated inflammation, particularly when immune complex contain IgG2.	12508778
Hyperexcitability Behavior	Altered Intercellular Communication	Hyperexcitability might be caused by a dysregulation of the intracortical GABAergic inhibitory circuitries and selective alteration of glutamatergic neurotransmission.	12509853
Crohn Disease	Altered Intercellular Communication	In chronic inflammatory conditions such as Crohn's disease, the migration of leukocytes from the circulation into the parenchyma and their activation within inflammatory sites are mediated in part by alpha4 integrins.	12510039
Inflammation	Altered Intercellular Communication	To determine whether organized mucosa-associated lymphoid tissue (MALT) is a normal component of the human efferent tear ducts or is acquired in reaction to chronic inflammation.	12511351
Inflammation, Malignant Childhood Neoplasm, Unknown (origin) (qualifier value), Fibrosis Assessment, Edema	Altered Intercellular Communication	The primary cause of SMM was edema in eight, malignant neoplasm in four, inflammation and/or fibrosis in five, and idiopathic in 12 patients.	12511673
Inflammation, Malignant Neoplasms, Vascular Diseases	Altered Intercellular Communication	At CT, SMM appears as a result of malignant neoplasms, inflammation, or vascular disorders.	12511673
Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Inflammation, Hepatocellular necrosis	Altered Intercellular Communication	The best predictors of fibrosis progression in CHC are the extent of serum aminotransferase elevations and the degree of hepatocellular necrosis and inflammation on liver biopsy.	12512034
Gingivitis, Dental Plaque	Altered Intercellular Communication	The amounts of plaque, gingival crevicular fluid, and clinical signs of gingival inflammation were intra-individually compared in 20 sets of the three test surfaces.	12512888
Inflammation, Dental Plaque	Altered Intercellular Communication	In the CSS, no significant differences were found between the surfaces in terms of amount of plaque and degree of gingival inflammation.	12512888
Inflammation, Dental Plaque	Altered Intercellular Communication	At the end of the EGS the restorative materials showed a significantly higher amount of plaque (CF versus E, P = 0.014; RC versus E, P = 0.034), but no significant differences were found in degree of gingival inflammation.	12512888
Inflammation, Dental Plaque	Altered Intercellular Communication	In condusion, the ceramic filling material was comparable to RC regarding plaque formation and gingival inflammation with customary oral hygiene.	12512888
Seizures, thymidine, Alcohol Withdrawal Delirium	Altered Intercellular Communication	The dopamine transporter (DAT) plays a key role in homeostatic regulation of dopaminergic neurotransmission and could thus be involved in the variability of two severe alcohol-withdrawal symptoms, alcohol-withdrawal seizure (AWS) and delirium tremens (DT).	12513948
Compartment syndromes, Inflammation, Cellulitis	Altered Intercellular Communication	These cases present a borderline form of infectious cellulitis, with severe local inflammation caused by a compartment syndrome.	12514517
Autoimmune Diseases, Inflammation, polychondritis	Altered Intercellular Communication	Relapsing polychondritis is a rare autoimmune disease, characterized by recurrent inflammation of cartilaginous tissues.	12514520
Hormone abnormality, Virilization, CTCAE	Altered Intercellular Communication	These hormonal disorders seem to have no influence on virilization, libido or sexual potency.	12514902
Inflammation, Technetium (99m-Tc) sulesomab	Altered Intercellular Communication	Mechanism of accumulation of 99mTc-sulesomab in inflammation.	12515870
Inflammation, Technetium (99m-Tc) sulesomab	Altered Intercellular Communication	99mTc-Sulesomab, the Fab fragment of anti-NCA-90, is used as an in vivo granulocyte labeling agent for imaging inflammation.	12515870
Lymphangioma, Hemorrhage, Pseudotumor, Rhabdomyosarcoma, Pathology, Acute dacryoadenitis, Varicosity, Sinusitis, Orbital Pseudotumor	Altered Intercellular Communication	Idiopathic inflammations of the orbit (pseudotumors) were the most frequent diagnoses seen as an emergency, followed by rhinological diseases with orbital consequences (exteriorized sinusitis or mucoceles), dysthyroid orbital pathologies, bleeding in lymphangiomas and varices, rhabdomyosarcoma, and acute dacryoadenitis.	12515938
Behavioral Symptoms, Inflammation, Neurologic Signs, Encephalomyelitis, Acute Disseminated	Altered Intercellular Communication	The clinical course confirms recent findings, suggesting that acute inflammation in encephalomyelitis disseminata may induce behavioural symptoms, which precede the onset of neurological signs.	12516315
Sepsis, Inflammation	Altered Intercellular Communication	Previous studies have shown that cytokines are activated early in acute inflammation and sepsis and may serve as indicators of clinical severity.	12516803
Sjogrens Syndrome", Communicable Diseases, mucosa-associated lymphoid tissue	Altered Intercellular Communication	Hepatis C virus infection is presently an exclusion criterion to classify Sjogren's syndrome; however, there are distinct clinicopathologic and biologic similarities between HCV-related and SS-related chronic inflammation of mucosa-associated lymphoid tissue and lymphoproliferation that suggest common pathogenetic pathways.	12516900
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays an important role in the pathogenesis of atherosclerosis.	12518120
Airway structure, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Exhaled nitric oxide (eNO) concentration measurement may allow for noninvasive estimation of severity of airways inflammation in asthma and other airways diseases.	12518628
Inflammation, Aspergillosis	Altered Intercellular Communication	The sphenoid lesions were caused by Aspergillosis in two patients and inflammation in two.	12518781
Cataract, Inflammation, Corneal Opacity	Altered Intercellular Communication	The complications of surgery and beta radiation consisted of conjunctiva inflammation 10 (8.6%), cornea opacities 4 (3.2%), gritty sensation 3 (2.6), cataract 1 (0.8%).	12518922
Pain Distress Question, Inflammation	Altered Intercellular Communication	The relief of pain, inflammation and restoration of mobility may be due to the effect of the transplanted adrenal graft, with the medullary component contributing to endorphin-like substance liberation and the cortical component contributing to glucocorticoid synthesis.	12519043
Inflammation	Altered Intercellular Communication	We therefore suggest that an IL-5 driven inflammation generates an eosinophil tissue phenotype that is characterized by a low IL-5R alpha expression.	12519389
Inflammation, Meningitis, Communicable Diseases, Encephalitis, Swelling	Altered Intercellular Communication	General infection leads to the development of meningitis or encephalitis, which is characterized by swelling of the brain due to inflammation.	12519399
Inflammation	Altered Intercellular Communication	Tetracyclines may act locally to moderate inflammation in the CNS.	12519399
Azoospermia, Non-obstructive	Altered Intercellular Communication	The patient's history, semen analyses, hormonal profile and testicular volume were analysed, and in addition to the histological results azoospermia was classified into obstructive and non-obstructive.	12521423
Non-obstructive azoospermia	Altered Intercellular Communication	In addition to the testicular volume and hormonal status, it can differentiate the obstructive from non-obstructive azoospermia.	12521423
Communicable Diseases, Inflammation	Altered Intercellular Communication	Irrigation and debridement was performed to evacuate joint debris, which could have served as a nidus for infection or inflammation.	12522407
AVP gene, Hypogonadotropic hypogonadism	Altered Intercellular Communication	Central diabetes insipidus with hypogonadotrophic hypogonadism was diagnosed by a water restriction test and different static and dynamic hormonal dosages.	12522940
Inflammation, Vascular Alterations	Altered Intercellular Communication	The specimens were evaluated for evidence of stromal inflammation, vascular alterations, and stromal and posterior epithelial degeneration.	12523881
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Previous studies have suggested that low-grade systemic inflammation is involved in the pathogenesis of type 2 diabetes mellitus.	12523922
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Low-grade systemic inflammation is associated with an increased risk of type 2 diabetes mellitus in middle-aged men.	12523922
Inflammation, Hypertension, CTCAE, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Inflammation could be one mechanism by which known risk factors for diabetes mellitus, such as obesity, smoking, and hypertension, promote the development of diabetes mellitus.	12523922
vascular inflammations	Altered Intercellular Communication	These data provide novel insight into the mechanism through which elevated levels of soluble CD40 ligand may reflect cardiovascular risk in humans and illustrate the potential value of interfacing high-resolution MRI with studies of vascular inflammation.	12524242
Inflammation, Diarrhea, Colitis	Altered Intercellular Communication	Collagenous colitis is characterised by diarrhoea, lymphocytic inflammation, and a thickened subepithelial collagen layer in the colorectal mucosa.	12524408
vascular inflammations, Collagen Diseases	Altered Intercellular Communication	Excess cardiovascular mortality complicates systemic rheumatic disease, suggesting an accelerated atheromatous process, which it has been proposed relates to the vascular inflammation common in such diseases.	12525387
Inflammation, "Alzheimers Disease", neuron death, Data types - Address	Altered Intercellular Communication	Inflammation is thought to promote neuronal cell death in Alzheimer's disease (AD).	12525884
Portal inflammation, Hepatitis	Altered Intercellular Communication	In all the examined specimens, 79.17% of them showed mild acute or chronic hepatitis, mainly presenting with degeneration of hepatocytes, mild portal inflammation.	12526295
Inflammation, Leukocytosis, Fever, CTCAE, Hypotension, CTCAE	Altered Intercellular Communication	There were significantly less patients with signs of inflammation (fever, leukocytosis, hypotension) in group A (group A n = 2; group B n = 9; p<0.05).	12527500
Steatohepatitis, Fibrosis Assessment, Inflammation, Chronic liver disease	Altered Intercellular Communication	Steatohepatitis, of either alcoholic or nonalcoholic etiologies, is ultimately diagnosed by clinical-pathologic correlation and is characterized histologically by lesions that differ from the portal-based chronic inflammation and fibrosis of most other forms of chronic liver disease.	12527713
Inflammatory abnormality of the eye	Altered Intercellular Communication	New therapeutic concepts in the management of ocular inflammation have led to the development of periocular and intravitreal injections.	12527830
Rheumatoid Arthritis, Inflammation, Vascular Diseases	Altered Intercellular Communication	Reduced arterial elasticity in rheumatoid arthritis and the relationship to vascular disease risk factors and inflammation.	12528107
Refractory anemias, Vascular Diseases, Inflammation, Coronary Artery Disease	Altered Intercellular Communication	In the present study, we sought to determine whether arterial elasticity was reduced and SVR was increased in RA patients compared with controls matched for coronary artery disease (CAD) status, and to relate the results to vascular disease risk factors, including measures of inflammation.	12528107
Refractory anemias, Inflammation	Altered Intercellular Communication	Associations of SAE and LAE with RA were independent of conventional risk factors, but were dependent on markers of inflammation.	12528107
Inflammation, "Alzheimers Disease", neuron death, Data types - Address	Altered Intercellular Communication	Given these NRG-1 actions, we hypothesized that the synaptic loss, gliosis, inflammation, and neuronal death occurring in Alzheimer disease (AD) is associated with altered expression of NRG-1 and its receptors (the erbB2, erbB3, and erbB4 membrane tyrosine kinases).	12528817
Inflammation, SLC22A5 gene	Altered Intercellular Communication	If the presence of the null CCR5delta32 allele results in a reduction of the chronic inflammation state present in SCD patients, this could lead to differential survival of SCD individuals who are carriers of the CCR5delta32 allele.	12532229
SLC22A5 gene	Altered Intercellular Communication	Based on a hypothesis that considers SCD as a chronic inflammatory condition, and since the CCR5 chemokine receptor is involved in directing a Th1-type immune response, we suggest that a Th1/Th2 balance can influence the morbidity of SCD.	12532229
Inflammation, Migraine Disorders	Altered Intercellular Communication	According to the hypothesis of neurovascular inflammation in migraine, these two cytokines could contribute to migraine pain generation.	12534582
Inflammation	Altered Intercellular Communication	Does inflammation or undernutrition explain the low cholesterol-mortality association in high-functioning older persons?	12534850
Inflammation, Hypocholesterolemia	Altered Intercellular Communication	To explore the effect of inflammation and undernutrition on the association between hypocholesterolemia and higher overall mortality in high-functioning older persons.	12534850
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	To investigate the relationship of inflammation and endothelial activation with insulin resistance and adiposity in type 2 diabetes.	12535753
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	HOMA IR correlated significantly with all measures of adiposity and markers of inflammation and endothelial dysfunction.	12535753
Inflammation	Altered Intercellular Communication	BMI was significantly associated with inflammation and endothelial activation, but with neither lipoproteins nor glycaemic control.	12535753
Inflammation, Hypertensive (finding), Cerebral Infarction, Endothelial dysfunction	Altered Intercellular Communication	The aim of this paper was to investigate endothelial dysfunction, platelet activation, and inflammation in elderly hypertensive patients and those complicated with cerebral infarction.	12536649
Refractory anemias, Inflammation, destruction joint	Altered Intercellular Communication	We report the case of a 49-year-old man with seropositive RA in whom large, rapidly progressive geodes in the wrists, hands, and feet contrasted with the absence of joint destruction, good functional tolerance, and moderate abnormalities of markers for inflammation.	12537273
Inflammation, Ischemia, Coronary heart disease	Altered Intercellular Communication	Elevated levels of C-reactive protein (CRP) are associated with an increased risk of coronary events, but whether inflammation is associated with inducible ischemia in patients with stable coronary disease is unknown.	12538423
Electrocardiogram: myocardial infarction (finding), Diabetes Mellitus, Cerebrovascular accident	Altered Intercellular Communication	Inflammation-sensitive plasma proteins, diabetes, and mortality and incidence of myocardial infarction and stroke: a population-based study.	12540619
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	The aim of this study was to examine, with dynamic contrast-enhanced MRI as the reference, if contrast-enhanced power Doppler ultrasonography (CE PDUS) of rheumatoid arthritis (RA) metacarpophalangeal (MCP) joints provides additional information for evaluation of synovial inflammation compared with PDUS.	12541125
Inflammation, Hyperplasia	Altered Intercellular Communication	Pathologic exam: 7 acute and chronic inflammation, 13 chronic inflammation with hyperplasia.	12541549
Inflammation	Altered Intercellular Communication	p53, bcl-2 proteins were assayed with immunohistochemical technique and EBV were assayed with polymerase chain reaction in 54 cases of NPC and 13 cases of chronic inflammation of nasopharyngeal epithelium (CINE).	12541691
Inflammation, polychondritis	Altered Intercellular Communication	Relapsing polychondritis is a relatively uncommon disease characterized by recurrence of progressive inflammation of cartilaginous structures.	12543181
Intraocular inflammation	Altered Intercellular Communication	In such cases, vitrectomy may be chosen as the therapeutic method to treat intraocular inflammation.	12543197
Inflammatory abnormality of the eye	Altered Intercellular Communication	After excision of the mass, ocular inflammation and other symptoms gradually disappeared.	12543198
HD Term Type, Inflammation	Altered Intercellular Communication	PIW and BMI correlate well with other anthropometric measures in patients treated with HD, but these measures do not correlate with markers of inflammation.	12543888
Inflammation, Disease	Altered Intercellular Communication	Eosinophil accumulation and activation are characteristic features of inflammation in allergic diseases and in host defense against parasites.	12544193
Inflammation, Hyperplasia	Altered Intercellular Communication	In contrast, 62 of the 78 deformable nodules (79.5%) showed histological features of hyperplasia and/or chronic inflammation.	12544319
Gastroesophageal reflux disease, Inflammation, Carditis	Altered Intercellular Communication	The aetiology of inflammation in cardiac mucosa at the gastro-oesophageal junction (carditis) is unclear, although gastro-oesophageal reflux has been suggested.	12544694
Gastroesophageal reflux disease, Inflammation	Altered Intercellular Communication	We were unable to establish either gastro-oesophageal or duodenogastric reflux as the predominant cause of inflammation in cardiac mucosa.	12544694
Inflammation, Neuroblastoma	Altered Intercellular Communication	A biopsy of the mass showed necrotic neuroblastoma with minimal associated inflammation.	12544797
Communicable Diseases, Inflammation, septic	Altered Intercellular Communication	Therefore, nitric oxide formation and lipid peroxidation were quantified in septic patients (SP) vs. patients with localized infection (IF) or without inflammation (C).	12544995
inflammation or infection, Joint Subluxations, Neck Pain	Altered Intercellular Communication	Today, due to the widened use of antibiotics and availability of MR imaging, some cases presenting with neck pain, resulting from the infectious inflammation of C1 and C2 but without pronounced subluxation, can be a challenging problem for most neurosurgeons.	12545265
Hepatitis	Altered Intercellular Communication	And genotype C may induce more severe the liver inflammation than genotype B may do.	12546732
Cardiomyopathies, Arthralgia, Diabetes Mellitus, Hormone abnormality, Fibrosis, Liver	Altered Intercellular Communication	Clinical signs of iron overload in patients include joint pains, cardiomyopathies, liver fibrosis and hormonal disorders including diabetes mellitus.	12547233
Follicle, Inflammation, Gastritis	Altered Intercellular Communication	With histologic examination, the presence and density of H. pylori organisms, the presence of follicular gastritis, the nature of inflammation, and the gastritis activity grade and overall gastritis score were assessed.	12548057
Inflammation	Altered Intercellular Communication	The relatively preserved oxyntic glands showed parietal cell hypertrophy and focal mild chronic inflammation.	12548171
Gastrointestinal inflammation	Altered Intercellular Communication	Elevated plasma levels of sCD40L in CD patients supposedly reflect activation of functional CD40L in the intestine and might be a marker of intestinal inflammation.	12548417
Keratopathy, Inflammation	Altered Intercellular Communication	Lipid keratopathy is mostly caused by corneal vascularization or chronic inflammation or is a consequence of systemic disorders of lipid metabolisms.	12548475
Atrophy of testis, Malignant Neoplasms	Altered Intercellular Communication	It may be confused with malignancy and related to testicular atrophy and hormonal imbalance.	12549646
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	This is the first study to demonstrate that selective COX-2 inhibition improves endothelium-dependent vasodilation and reduces low-grade chronic inflammation and oxidative stress in coronary artery disease.	12551863
Cancer-related fatigue, Chronic Kidney Diseases	Altered Intercellular Communication	Biochemical and hormonal disturbances in calcium-phosphate storage accompanying chronic renal failure (CRF) lead to the loss of bone mass and the destruction of bone microarchitecture.	12552245
Herpes Simplex Infections	Altered Intercellular Communication	Post mortem histology of the larynx showed an acute pseudomembranous inflammation with the classical morphology of HSV infection.	12553120
Vitreous inflammatory cells	Altered Intercellular Communication	The vitreous inflammation subsided greatly after the initial treatment but flared up after the second dilatation and curettage for incomplete abortion 5 days after the vitrectomy.	12553368
Communicable Diseases, Inflammation	Altered Intercellular Communication	Calcitonin precursors are sensitive markers of inflammation and infection.	12555296
Inflammation, Temporal Arteritis	Altered Intercellular Communication	The history of persistent fronto-occipital headaches and palpation of bilateral tortuous temporal arteries with a decreased pulse suggested the diagnosis of temporal arteritis, particularly in the presence of marked laboratory signs of inflammation and the coronary angiograph findings.	12555352
Uremia, Inflammation	Altered Intercellular Communication	Markers of chronic inflammation, acute-phase reactants, and growth factors may be concomitantly involved in a number of pathologic processes in the general population and uremic patients.	12556068
Inflammation	Altered Intercellular Communication	Our results indicate that systemic inflammation in peritoneal dialysis patients is associated with increased plasma VEGF and bFGF but not TGFbeta1.	12556068
Inflammation, Communicable Diseases, Fibrosis Assessment, Airway Obstruction, Damage	Altered Intercellular Communication	Cystic fibrosis (CF) patients have abnormally viscid bronchial secretions that cause airway obstruction, inflammation, and infection that leads to lung damage.	12556258
Hepatic inflammation, Hepatitis C	Altered Intercellular Communication	Hepatitis C virus-seropositive whites with the RANTES -403-A allele were less likely to have severe hepatic inflammation compared with those without (odds ratio, 0.34; P = 0.03).	12557141
Hepatic inflammation, Hepatitis, Chronic	Altered Intercellular Communication	Expression of CCR5 and RANTES may be important in the modulation of hepatic inflammation and response to interferon therapy in chronic hepatitis C.	12557141
Inflammation, Autoimmune Diseases, GYPB gene, Destruction (action), "Sjogrens Syndrome", Dryness (characteristic), Exocrine pancreatic insufficiency	Altered Intercellular Communication	Sjogren's syndrome (SS) represents autoimmune disease characterized by chronic inflammation, destruction and insufficiency of exocrine glands, particularly salivary and lacrimal glands, accompanied by dryness of mouths and eyes.	12557619
Inflammation, Angina Pectoris	Altered Intercellular Communication	Inflammation and immune system response against unstable angina and its relationship with coronary angiographic findings.	12558124
Inflammation, Atherosclerosis	Altered Intercellular Communication	Evidence suggests that inflammation plays a key role in the pathogenesis of atherosclerosis.	12558125
Inflammation, Acute Coronary Syndrome, Angina Pectoris	Altered Intercellular Communication	CRP as a marker of inflammation is significantly increased in patients with AMI and unstable angina shortly after the onset of symptoms (after a period of 12 hours), supporting the hypothesis of an activation of inflammatory mechanisms in patients with an acute coronary syndrome or AMI.	12558125
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histological examination showed perifollicular fibrosis and lymphocytic inflammation around the isthmus and infundibular areas of the follicles.	12558623
Granulomatous inflammation	Altered Intercellular Communication	The lesions did not respond to topical steroids and histopathologic examination of biopsy specimens showed granulomatous inflammation.	12558845
Gingivitis, Gingiva	Altered Intercellular Communication	In addition, seven sites with both P. gingivalis and Bacteroides forsythus showed a correlation with gingival inflammation.	12558934
Inflammation, Hypospadias, Verrucous carcinoma	Altered Intercellular Communication	This observation suggests that hypospadias and secondary chronic inflammation of the scrotal skin, caused by prolonged contact with urine, may contribute to an increased risk of verrucous carcinoma.	12559309
Congestive heart failure	Altered Intercellular Communication	Hormonal profile in patients with congestive heart failure.	12559538
Inflammation, Myocardial, Coronary Artery Disease	Altered Intercellular Communication	Myocardial damage, inflammation and thrombin inhibition in unstable coronary artery disease.	12559940
Tissue damage, Inflammation, Myocytes, Cardiac	Altered Intercellular Communication	Myocardial cell injury was related to a high degree of inflammation, only some of which is an acutephase response due to tissue damage.	12559940
Inflammation, Thrombosis	Altered Intercellular Communication	The rise in fibrinogen was sustained, which might reflect low grade inflammation with long-term risk of thrombosis.	12559940
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Fatty degeneration	Altered Intercellular Communication	NAFLD was associated with a spectrum of changes in the liver ranging from mild steatosis to more significant steatosis with inflammation and fibrosis.	12560853
Inflammation, Tissue Adhesions	Altered Intercellular Communication	The most common reason for conversion was difficult adhesions and inflammation around the gallbladder.	12560902
Electroconvulsive Therapy, Inflammation, Pain Distress Question	Altered Intercellular Communication	These results suggest that some, but not all, CECS patients may be more susceptible to the pain associated with eccentric contractions that is thought to be the cause of damage and inflammation of connective tissue.	12560956
Trauma, Nervous System	Altered Intercellular Communication	Prolonged and heavy use can lead to neuronal damage, neurotransmitter depletion and receptor supersensitivity.	12562108
Communicable Diseases, Inflammation	Altered Intercellular Communication	Adverse reactions after cosmetic lip augmentation with synthetic implant materials include inflammation, infection, and extrusion of and foreign body reaction to the implant.	12562355
Inflammation	Altered Intercellular Communication	Inflammation is thought to occur early during the relapsing-remitting phase of MS (RRMS), whereas in the later phases of MS such as secondary progressive MS (SPMS), inflammation tends to diminish.	12562396
Refractory anemias, Inflammation	Altered Intercellular Communication	Our results provide evidence for an activation of neutrophil granulocytes at site of inflammation in RA and indicate that lactoferrin surface expression represents a reliable neutrophil activation marker.	12563671
Inflammation	Altered Intercellular Communication	There is differential angiogenesis at an early stage of inflammation, with major pathogenic and therapeutic implications.	12563678
Undifferentiated Carcinoma of Colon, Inflammation, Epithelial, Hodgkin Disease	Altered Intercellular Communication	It frequently misdiagnosed as chronic inflammation, malignant granulomatosis, epithelial cancer, and undifferentiated cancer, etc.	12563965
Premalignant, Benign prostatic hypertrophy, Inflammation, Carcinoma	Altered Intercellular Communication	Distribution of inflammation, pre-malignant lesions, incidental carcinoma in histologically confirmed benign prostatic hyperplasia: a retrospective analysis.	12565775
Inflammation	Altered Intercellular Communication	In particular, inflammatory aspects were associated with BPH in a high percentage of cases (43.1% =1700 cases), predominantly as chronic inflammation.	12565775
Inflammation	Altered Intercellular Communication	On the contrary, the distribution of inflammatory aspects (p<0.001) and AAH (p=0.003) significantly varied according to prostate volume, and particularly in regards to chronic inflammation, there was a trend to increase depending on the prostate volume (p=0.002).	12565775
Inflammation	Altered Intercellular Communication	Chronic inflammation caused by silicone oil might be involved in the development of SO.	12571773
Inflammation	Altered Intercellular Communication	Involvement and severity of inflammation, as well as vascularization, were scored according to a new 3-point scale.	12571840
Refractory anemias, Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	To examine the expression patterns of interkeukin-18 (IL-18) in synovial biopsy tissue of patients with rheumatoid arthritis (RA), and to determine whether expression of this primary cytokine is related to the expression of other cytokines and adhesion molecules and related to the degree of joint inflammation.	12571842
Refractory anemias, Inflammation	Altered Intercellular Communication	Our results show that expression of IL-18 is associated with that of IL-1beta and TNFalpha and with local inflammation in the synovial tissue of patients with RA.	12571842
Polycystic Kidney, Autosomal Dominant, Tubulointerstitial atrophy, Fibrosis Assessment, Kidney Failure	Altered Intercellular Communication	Because the mechanism ofthe renal failure in ADPKD includes a cystic growth and tubulointerstitial atrophy and fibrosis, we studied the associations between 2 polymorphisms in the TGF-beta1 gene, which are known to be associated with chronic tubulointerstitial inflammation, and ADPKD progression in Korean patients.	12572925
Inflammation, Atherosclerosis	Altered Intercellular Communication	If inflammation were on the intermediate causal pathway between alcohol intake and atherosclerosis, then genetic determinants of enhanced inflammation would be expected to modify this relationship.	12574550
Inflammation, Atherosclerosis	Altered Intercellular Communication	These data support the hypothesis that inflammation forms part of the intermediate causal pathway between alcohol intake and atherosclerosis.	12574550
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	All subjects were administered a neurological examination, an infection/inflammation (I/I) examination, and an interview to elicit recent I/I history at baseline (within several days of stroke onset) and again approximately 2 months later.	12574559
Inflammation, Takayasu Arteritis, Vasculitis, CTCAE, Arteritis	Altered Intercellular Communication	In the absence of other vasculitis or inflammation markers, Takayasu's arteritis was diagnosed and steroid therapy was started.	12574956
Inflammation, Dysplasia, Metaplasia, Primary malignant neoplasm	Altered Intercellular Communication	Pathology reports were reviewed for histologic evidence of inflammation, atypia, metaplasia, dysplasia, or cancer.	12576887
Inflammation, cisplatin/mitomycin/vinblastine protocol, Mitral Valve Prolapse Syndrome	Altered Intercellular Communication	Inflammation and genetics may play a role in the pathogenesis of mitral valve prolapse (MVP).	12578333
Cystic medial necrosis of aorta, Inflammation, Fibrosis Assessment, Atherosclerosis	Altered Intercellular Communication	These specimens were systematically re-evaluated, and graded according to the severity of seven histopathological conditions: fibrosis, atherosclerosis, medionecrosis, cystic medial necrosis, smooth muscle cell orientation, elastic fiber fragmentation, and inflammation.	12578337
Inflammation	Altered Intercellular Communication	Patients with no ultrasonographic changes presented histological signs of initial inflammation such as isolated inflammatory cells around the vasa vasorum and/or in the adventitial layer.	12578748
Inflammation	Altered Intercellular Communication	The authors conclude that IVIG is safe and effective to treat even chronically debilitated patients who have the disease, presumably because it ameliorates smoldering inflammation.	12578938
Inflammatory Myofibroblastic Tumor, Myositis, CTCAE 5.0, Orbital Pseudotumor	Altered Intercellular Communication	According to radiologic and surgical findings, focal mass within orbit was the most frequent subtype (43%), followed by lacrimal inflammatory pseudotumor (32%), diffuse orbital inflammation (10%), myositis (8%).	12579650
Neuritis, Inflammation, Eyelid Neoplasms	Altered Intercellular Communication	Perineuritis (2%), periscleritis (2%), acute inflammation (2%) and eyelid pseudotumor (1%) were rare clinical findings.	12579650
Corneal edema, Inflammation, Hemorrhage, Abnormally opaque structure (morphologic abnormality)	Altered Intercellular Communication	After the operations the rate of continued corneal edema was 1.3% (3 eyes); posterior capsular opacity was 3.0% (7 eyes); inflammation was 0.9% (2 eyes); discentral location of intraocular lens was 0.4% (1 eye); leakage of wound was 0.9% (2 eyes); hemorrhage in the anterior chamber was 0.4% (1 eye).	12580045
Acute and chronic inflammation	Altered Intercellular Communication	Our findings also indicate that the VLA-4/VCAM-1 system is important for chronic T cell inflammation in muscle, in line with findings in other "hidden" organs like joints and the central nervous system.	12580864
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide (NO) has been proposed as novel a non-invasive marker of airway inflammation.	12580910
Inflammation, Dermatologic disorders	Altered Intercellular Communication	The patient reported that his mother and aunt had a similar skin disorder, which initially began with inflammation, but healed leaving lax skin in its wake.	12581150
Fibrous, Inflammation	Altered Intercellular Communication	Fewer plaques from patients being treated with fish oil had thin fibrous caps and signs of inflammation and more plaques had thick fibrous caps and no signs of inflammation, compared with plaques in patients in the control and sunflower oil groups (odds ratio 0.52 [95% CI 0.24-0.89] and 1.19 [1.02-1.57] vs control; 0.49 [0.23-0.90] and 1.16 [1.01-1.53] vs sunflower oil).	12583947
Fibrosis, Liver, Inflammation, Fibrosis Assessment, Thrombophilia	Altered Intercellular Communication	Whether the association of such thrombophilic conditions with advanced fibrosis is a primary or secondary phenomenon and whether their development in combination with local inflammation accelerate the progression of liver fibrosis need further evaluation.	12584224
palladium, Inflammation	Altered Intercellular Communication	In this retrospective analysis, we evaluated possible relationships between RRF, inflammation and initial PTR in patients starting PD and the impact of these factors on patient survival.	12584284
palladium, Inflammation	Altered Intercellular Communication	These results indicate that in patients starting PD, low initial RRF is associated with inflammation, and low RRF and inflammation are both associated with high overall mortality.	12584284
palladium, Inflammation	Altered Intercellular Communication	These results indicate the importance of RRF and inflammation as predictors of mortality in PD patients whereas the predictive power of PTR as such may lose its significance if these two parameters are taken into consideration.	12584284
Interstitial inflammation	Altered Intercellular Communication	An open pulmonary biopsy revealed an interstitial inflammation, localized in the alveolar walls.	12585974
Interstitial inflammation, Herpesviridae Infections	Altered Intercellular Communication	We concluded that as a consequence of herpes infection, endothelial involvement and interstitial inflammation supervene, with thickening of vascular walls and partial obliteration of the vessel lumen.	12585974
Inflammation, Erythema Nodosum	Altered Intercellular Communication	Surprisingly, erythema nodosum, an inflammation of the adipose tissue of the skin, has rarely been described.	12587841
Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	It is often difficult to differentiate extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) from non-neoplastic inflammatory conditions.	12588443
Inflammation	Altered Intercellular Communication	The specimens were classified according to the degree of inflammation into three groups (mild, moderate and severe).	12588460
Inflammation	Altered Intercellular Communication	These results suggest that CD14 may be down-regulated during the development of inflammation and/or dendritic cells might infiltrate chronically inflamed gingival tissue.	12588460
Airway structure, Asthma	Altered Intercellular Communication	AR, even in the absence of asthma, is associated with increased levels of exhaled nitric oxide (ENO) and hydrogen peroxide (H(2)O(2)) in exhaled breath condensate, 2 noninvasive markers of lower airway inflammation.	12589351
Airway structure, Asthma	Altered Intercellular Communication	ENO might be a more specific marker of the lower airway inflammation present in asthma.	12589351
Inflammation	Altered Intercellular Communication	These findings are consistent with a role for genetic determinants of inflammation in the development of T2DM in both Native Americans and Caucasians.	12589429
Inflammation	Altered Intercellular Communication	We conclude that large increase in serum non-esterified EPA and DHA, which can only be attained by supplementation, might increase inflammation in vascular endothelium.	12589702
Sinusitis	Altered Intercellular Communication	Chronic sinusitis is characterized by persistent chronic inflammation of the sinus system and local expression and release of various cytokines, such as IL-1 beta, IL-4, IL-6, IL-8, TGF-beta and TNF-alpha are deeply involved in the pathogenesis of the disease.	12589850
Inflammation, Fever, CTCAE, Necrosis, Rhabdomyolysis, Septic Shock	Altered Intercellular Communication	We report the first case outside the UK meeting the criteria for this new entity (septic shock without fever in an injection drug user, local and systemic inflammation, rhabdomyolysis and tissue necrosis at the injection site).	12592088
Inflammation, Keratosis	Altered Intercellular Communication	5-Fluorouracil is used extensively to treat actinic keratoses as there is selective excessive uptake of 5-fluorouracil in rapidly dividing cells, thus causing inflammation in lesional skin.	12592090
Inflammation, Gastroesophageal Junction Adenocarcinoma	Altered Intercellular Communication	We report 2 cases of inflammation occurring on clinically normal skin after fluorouracil had been administered parenterally for carcinoma of the oesophagogastric junction and lower third of the oesophagus, respectively.	12592090
Trigeminal Neuralgia	Altered Intercellular Communication	VIP indeed participates in the attack of trigeminal neuralgia in the local region, the role of VIP may be relating to enhancing the effects of substance P in local neurogenic inflammation.	12593198
Inflammation, Rupture, Plaque, Atherosclerotic	Altered Intercellular Communication	The role of inflammation and mast cell activation has been implicated in atherosclerotic plaque destabilization and rupture.	12593498
Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	The frequency of ulceration and inflammation associated with the calcinosis deposits decreased with treatment.	12594118
Tenosynovitis	Altered Intercellular Communication	Sonography can be used for diagnosing inflammatory conditions affecting tendons, including acute and chronic tenosynovitis.	12594802
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To investigate the relationship between inflammation markers and content of pyridinium crosslinks in hydrolysates of synovial tissue and to specify the significance of urinary excreted pyridinoline, released primarily from collagen I and II of bone and cartilage, and deoxypyridinoline released especially from collagen I of bone and dentin, dependent on disease activity in rheumatoid arthritis (RA).	12595629
Refractory anemias	Altered Intercellular Communication	We suggest that increased crosslinking of mature collagen in the synovial tissue of RA is related to an inflammation-dependent regulation of collagen synthesis in activated synovial fibroblasts, in which lysyl oxidase represents the final enzymatic step for crosslinking.	12595629
Inflammation, Coronary heart disease	Altered Intercellular Communication	Elevation of C-reactive protein (CRP), among other markers of inflammation, is associated with an increased risk for cardiac events in patients with known coronary diseases and in apparently healthy individuals.	12595841
Inflammation	Altered Intercellular Communication	The protein encoded by the CARD15 gene is expressed in peripheral monocytes and regulates apoptosis and NF-kappaB activation, factors which play an important role in inflammation.	12595906
Inflammation, Asthma	Altered Intercellular Communication	Increased ECP levels reflect the degree of inflammation and correlate with the clinical picture severity in asthmatic patients.	12596625
Aneurysm, Inflammation	Altered Intercellular Communication	A significant relation between the method of direct C. pneumoniae diagnosis, aneurysm symptoms and histologically detected inflammation in its wall was confirmed.	12597340
Asphyxia, Hemorrhage, Inflammation	Altered Intercellular Communication	None of 30 patients undergone epiglotiotomy had asphyxia, inflammation diffuse or serious hemorrhage.	12599774
Inflammation	Altered Intercellular Communication	After application of Gd-DPTA, 5 of 57 patients (9%) demonstrated contrast enhancement indicating local inflammation.	12600434
Inflammation	Altered Intercellular Communication	There may be additional information by MRI about local inflammation.	12600434
Pain Distress Question, Inflammation	Altered Intercellular Communication	A prospective study comparing the histological and MRI findings should be performed to answer the question, if pain is really associated with inflammation.	12600434
Inflammation	Altered Intercellular Communication	Senescent HSCs showed higher expression of inflammation and stress-associated genes as compared with early passage HSCs.	12601363
Fever, CTCAE, inflammation or infection	Altered Intercellular Communication	A reliable marker to discriminate infectious inflammations from drug-related and tumor-associated fever is still lacking.	12601488
Fever, Hematological Disease	Altered Intercellular Communication	Febrile inflammatory conditions are frequent in patients with hemato-oncological diseases.	12601488
Appendicitis, CTCAE, Acute inflammation	Altered Intercellular Communication	In acute appendicitis patients 66.1% were with acute inflammation, in 29% complicated and 4.8% negative appendicitis.	12601980
Inflammation	Altered Intercellular Communication	Malacoplakia is a chronic inflammation which usually arises in the urinary tract of older women and, rarely, in the female genital tract.	12602074
Inflammation	Altered Intercellular Communication	Hemodialysis patients suffer from chronic inflammation due to intradialytic contact of blood with artificial materials.	12602466
Arthralgia, Inflammation	Altered Intercellular Communication	Since the age of 31, the patient also presented psoriatic nail changes involving all his fingernails, without joint pain or inflammation.	12602977
Granulomatous inflammation, Aneurysm	Altered Intercellular Communication	Cranial magnetic resonance testing magnetic resonance tomography (MRT) revealed a granulomatous inflammation surrounding the site of the aneurysm and affecting optochiasmatic structures.	12603290
Airway structure, Respiratory Hypersensitivity, AHR wt Allele	Altered Intercellular Communication	It has been suggested that subjects with alpha-antitrypsin (AAT) deficiency, lacking a major antiprotease defence against airway inflammation, might be more susceptible of development of airway hyperresponsiveness (AHR).	12603503
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	In gastric mucosal samples H. pylori was cultured, genotyped and histologically assessed, while inflammation, activity and intestinal metaplasia were graded.	12603613
Inflammation, Nipples	Altered Intercellular Communication	On the background of the reviewed literature, intensive investigations should only be performed in neonates and infants if bloody nipple discharge is unilateral, continues, expands in size or shows signs of inflammation.	12603810
Inflammation	Altered Intercellular Communication	The process consuming protein C and APC may be related to the simultaneous ongoing neutrophil and monocyte activation within the liver graft, indicating a regulatory role for APC in inflammation.	12605111
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	Level of glucocorticoid receptor mRNA expression in iris tissue and postoperative ocular inflammation in patients with uveitis.	12605259
Inflammation	Altered Intercellular Communication	This association may not be fortuitous and be related to inflammation of the facet joint in SpA.	12605323
Inflammation, Decreased renal function	Altered Intercellular Communication	This was not due to decreased renal function, ongoing inflammation or neutrophil activation.	12605707
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Smokers have elevated C-reactive protein (CRP), an indicator of systemic inflammation and a marker for increased risk for cardiovascular disease (CVD).	12607808
Inflammation	Altered Intercellular Communication	EGG parameters were affected by vocal lesion and its intrinsic inflammation.	12608283
Intraocular inflammation, Uveitis	Altered Intercellular Communication	To analyse the correlation between the anti-retinal antibodies (ARA) and intensity of intraocular inflammation in patients with endogenous posterior uveitis.	12608307
Intraocular inflammation, Uveitis	Altered Intercellular Communication	Intraocular inflammation intensity was scored on standard uveitis grading system prepared by BenEzra et al.	12608307
Retinal Vasculitis, Vitreous inflammatory cells	Altered Intercellular Communication	High correlation was found in first control between serum ARA level and the degree of vitreous inflammation and the presence of fresh vessels sheathing, characteristic for retinal vasculitis.	12608307
Retinal Vasculitis, Vitreous inflammatory cells	Altered Intercellular Communication	And at the end of observation no correlation was found, neither between serum ARA levels and the activity of vitreous inflammation, nor between the ARA levels and retinal vasculitis intensity.	12608307
Autoimmune Diseases, Idiopathic posterior uveitis, Intraocular inflammation	Altered Intercellular Communication	The assessment of serum ARA in patients with idiopathic posterior uveitis can act as an indicator for intraocular inflammation intensity and can reflect the retinal autoimmunity.	12608307
Inflammation, Dystonia Musculorum Deformans, Loss of neurons, Dystonia Disorders	Altered Intercellular Communication	Beyond these apparent changes in neuronal size and spacing in dystonia brains, there was no indication of neuron loss, inflammation, DNA strand breaks, or altered distribution of torsin-like immunoreactivity, supporting a functional rather than degenerative etiology of early onset torsion dystonia.	12609485
Alzheimers Disease", Apolipoprotein E, Inflammation, Data types - Address	Altered Intercellular Communication	The allele E4 of apolipoprotein E (apoE) is an important risk factor for Alzheimer's disease (AD) and the chronic brain inflammation which is associated with AD is more pronounced in subjects who carry this allele.	12609489
Gastroesophageal reflux disease, Inflammation	Altered Intercellular Communication	The correlation between the traditionally accepted histological markers of gastro-oesophageal reflux disease in squamous mucosa and 24 hour pH testing was predominantly negative, with the exception of neutrophil inflammation in the squamous mucosa of patients with complicated reflux disease.	12610100
Inflammation	Altered Intercellular Communication	Histopathology of the optic nerve sheath area revealed fibroadipose tissue containing numerous arteries with intimal thickening, and mild mural inflammation consisting predominantly of lymphocyte with occasional giant cells.	12610827
Myositis	Altered Intercellular Communication	The histopathology was unchanged and there were no signs of increased muscle inflammation or of expression of cytokines and adhesion molecules in the muscle biopsies.	12610846
Myositis	Altered Intercellular Communication	The home exercise program was considered as not harmful to the muscles regarding muscle inflammation and function.	12610846
Inflammation, cardiac event, Coronary Artery Disease, Atherosclerosis	Altered Intercellular Communication	Blood histamine is associated with coronary artery disease, cardiac events and severity of inflammation and atherosclerosis.	12611642
Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	The clinical relevance of ECC-related systemic inflammation varies with the patient, and such inflammation may be accompanied by intermittent organ dysfunction and an increased catecholamine requirement.	12611732
Airway structure, Asthma, Failure (biologic function)	Altered Intercellular Communication	This may partly explain persistent airway inflammation during chronic ICS treatment and failure to achieve adequate asthma control in some patients.	12612295
Airway structure	Altered Intercellular Communication	In addition to conventional lung function tests and symptom questionnaires, eNO is a suitable measure of airway inflammation and its application may reinforce the power of epidemiological surveys on respiratory health.	12612304
Inflammation, Deep thrombophlebitis	Altered Intercellular Communication	DVT and HO are both associated with laboratory parameters of non-infectious inflammation.	12612623
Esophagitis	Altered Intercellular Communication	The means to effectively control symptoms and improve esophageal inflammation in these patients is to reduce esophageal acid exposure.	12612717
Epilepsy	Altered Intercellular Communication	Physical and hormonal profile of male sexual development in epilepsy.	12614402
Uveitis	Altered Intercellular Communication	Five months after PK surgery, the graft was clear and no signs of extraocular or intraocular inflammation were present.	12614765
Inflammation, Neuronal loss in central nervous system	Altered Intercellular Communication	These findings suggest neuronal loss and reactive gliosis without inflammation, consistent with brain biopsy findings showing astrocytic proliferation unaccompanied by lymphocytic infiltrates.	12614932
Bone Marrow Diseases, Encephalopathy, CTCAE 5.0, Inflammation	Altered Intercellular Communication	Pathological and virological assessment of acute HTLV-I-associated myelopathy complicated with encephalopathy and systemic inflammation.	12614936
Inflammation	Altered Intercellular Communication	Determination of HTLV-I viral loads demonstrated increased levels in the CSF relative to the peripheral blood and may be associated with widespread inflammation.	12614936
Communicable Diseases, Inflammation	Altered Intercellular Communication	Inflammation and infection result in telomere shortening in immune cells.	12615525
APP gene, Inflammation, Aortic Aneurysm, Abdominal, Cardiovascular Diseases	Altered Intercellular Communication	Abdominal aortic aneurysms (AAA) are characterized by extensive transmural inflammation and C-reactive protein (CRP) has emerged as an independent risk factor for the development of cardiovascular disease.	12615785
Pancreatic Hemorrhage, CTCAE, Inflammation, Aneurysm	Altered Intercellular Communication	A condition of massive pancreatic hemorrhage without relation to injury, inflammation, or aneurysm is described.	12616434
Inflammation	Altered Intercellular Communication	Histological evaluation of liver specimens of this patient showed portal inflammation and the presence of pigmented macrophages.	12621911
Dental Plaque, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Control of denture plaque and mucosal inflammation in denture wearers.	12622017
Inflammation, Vaso-Occlusive Crisis	Altered Intercellular Communication	Abnormal nitric oxide-dependent regulation of vascular tone, adhesion, platelet activation, and inflammation contributes to the pathophysiology of vaso-occlusion.	12622584
Inflammation, Earache, Myringitis	Altered Intercellular Communication	the most characteristic symptom of acute bullous myringitis (inflammation of the tympanic membrane) is a sudden onset of severe ear pain.	12623153
Conjunctivitis	Altered Intercellular Communication	Symblepharon, increased inferior fornix depth, presence of conjunctival goblet cells, and the degree of conjunctival inflammation.	12623807
Conjunctivitis	Altered Intercellular Communication	Conjunctival inflammation was clinically but not statistically reduced.	12623807
Intraocular inflammation	Altered Intercellular Communication	Vitreous aspiration needle tap in the diagnosis of intraocular inflammation.	12623828
Inflammatory abnormality of the eye	Altered Intercellular Communication	The remaining patients were treated with immunosuppressives for the ocular inflammation and showed clinical improvement over the follow-up period.	12623828
Inflammation, Heat-Shock Response, Infection caused by Helicobacter pylori	Altered Intercellular Communication	In our study population, H pylori infections defined by seropositivity have no relationship with levels of classic cardiovascular risk factors or markers of systemic inflammation, except for elevated levels of immune reactions to mycobacterial heat shock protein 65.	12624280
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays an important role in the development of atherosclerosis.	12624309
Inflammation, Traumatic injury, Pain Distress Question	Altered Intercellular Communication	During injury or inflammation, paracrine sensitization of peripheral sensory neurons by immune cells contributes to the sensation of pain.	12624778
Fibromyalgia	Altered Intercellular Communication	The same hormonal factors responsible for a delayed menarche and a reduced fertility may be relevant in the development of fibromyalgia.	12624804
Acute Lung Injury, Pneumonitis	Altered Intercellular Communication	Persistent elevations of proinflammatory cytokines in the lungs are associated with increased mortality from acute lung injury (ALI), suggesting that the degree of pulmonary inflammation is an important determinant of clinical course in ALI.	12626346
Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	Platelet-activating factor (PAF) is a proinflammatory phospholipid that may contribute to inflammation in the acute respiratory distress syndrome (ARDS).	12626982
Respiratory Distress Syndrome, Adult, Inflammation	Altered Intercellular Communication	PAF-AH activity in the lungs of ARDS patients may regulate inflammation caused by PAF and related oxidized phospholipids generated in the inflammatory response.	12626982
Fibrous, Inflammation, Aortitis Syndrome	Altered Intercellular Communication	Considering the presence of concomitant aortitis syndrome, it is strongly suggested that the overgrowth of fibrous tissue was promoted as a reaction to chronic inflammation.	12627073
Inflammation, Superficial ulcer, Genitalia	Altered Intercellular Communication	The mucous membranes of the eyes, mouth and genitalia also showed marked inflammation, most prominent were large erosions in the mouth.	12627339
Inflammation, Chemical Gastritis	Altered Intercellular Communication	MDA levels were significantly correlated with the extent of the mucosal inflammation and with disease activity in patients with reactive gastritis.	12628220
Synovitis	Altered Intercellular Communication	This demonstrates that synovitis is linked to inflammation-related blood vessel density of the synovial tissues.	12628600
Airway structure, Asthma, Inflammatory disorder	Altered Intercellular Communication	Exhaled nitric oxide (NO) levels are significantly elevated in patients with inflammatory airways disorders such as asthma, and the measurement of exhaled NO has been proposed as a noninvasive marker of airways inflammation.	12628874
Inflammation	Altered Intercellular Communication	A series of examinations revealed a calf mass caused by wear debris of total knee prosthesis and subsequent inflammation of the knee joint.	12629618
Inflammation, Biliary calculi	Altered Intercellular Communication	Acute acalculous cholecystitis is inflammation of the gallbladder in the absence of gallstones.	12630651
Granulomatous inflammation	Altered Intercellular Communication	Histopathology findings revealed a granulomatous inflammation with epithelioid cells.	12632276
Inflammation	Altered Intercellular Communication	Role of the tissue factor pathway in synovial inflammation.	12632417
Refractory anemias, Rheumatoid Arthritis, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	Synovial tissue specimens obtained from 10 patients with rheumatoid arthritis (RA) and 12 patients with osteoarthritis (OA) were scored histologically for inflammation and fibrin content.	12632417
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	There was a significant difference between the RA and OA groups in terms of synovial inflammation, with more inflammation observed in the RA group.	12632417
Inflammation	Altered Intercellular Communication	Most importantly, TF activity was associated with fibrin (P = 0.024) and with histologic inflammation (P = 0.03) scores.	12632417
Refractory anemias, Inflammation, Disseminated Intravascular Coagulation	Altered Intercellular Communication	Our results show that TF expression in arthritic synovial tissue favors extravascular coagulation and may play a role in inflammation in RA.	12632417
Inflammation, Ulcer	Altered Intercellular Communication	Histological examination showed that all animals developed severe inflammation, especially in the area close to ulcers, and multifocal lymphoid follicles appeared in the lamina propria and submucosa.	12632510
Lambert-Eaton Myasthenic Syndrome, Neuromuscular Diseases	Altered Intercellular Communication	Lambert-Eaton myasthenic syndrome (LEMS) is a neuromuscular disorder characterized by defective neurotransmitter release at presynaptic terminals.	12632823
Aneurysmal, Inflammation, Tissue Adhesions	Altered Intercellular Communication	The surgical approach is technically more difficult because of inflammation and adhesions between the aneurysmal sac and contiguous structures which make dissection and aorto-iliac clamping more demanding.	12633044
Inflammation, Acute otitis media, Infectious Otitis Media	Altered Intercellular Communication	Two potent mediators of acute inflammation, histamine and leukotriene B4 (LTB4), have been shown to play important roles in the pathogenesis and clinical course of acute otitis media (AOM) in children.	12633920
Respiratory Distress Syndrome, Adult, Inflammation	Altered Intercellular Communication	These findings suggest that MIF plays a crucial pathological role leading to alveolar inflammation in ARDS.	12635141
Respiratory Distress Syndrome, Adult, Inflammation	Altered Intercellular Communication	Anti-MIF and early glucocorticoid therapy may represent a novel therapeutic approach for reducing alveolar inflammation in ARDS.	12635141
Coma, Post-Head Injury, Glaucoma, CTCAE, Hyphema, Intraocular inflammation	Altered Intercellular Communication	Postoperatively, persistent intraocular inflammation was seen in four eyes, secondary glaucoma in four eyes, transient hyphema and/or hemovitreous in four, IOL decentration in two, and post-traumatic haptic detachment in one eye.	12635676
Malignant Neoplasms	Altered Intercellular Communication	Dental status, oral mucosal status, oral hygiene status, oral mucosal inflammation, and oral mucosal friction were assessed by observational examinations; suspected malignancies were also noted.	12635775
Cartilage destruction, Inflammation, Joints, Degenerative polyarthritis	Altered Intercellular Communication	This process is regulated by cartilage derived IL-1 antagonists, and is implicated in cartilage destruction and synovial inflammation in OA and RA joints.	12635941
Inflammation	Altered Intercellular Communication	F-18 FDG PET presented synovial inflammation in the left sterno-clavicular joint but no relevant tracer uptake on clavicles or breastbones.	12635949
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Inflammation and coagulation: direct mediators of physical function in the elderly?	12637140
Uremia, Inflammation	Altered Intercellular Communication	The presence of cTnT is linked to oxidative stress, inflammation and uraemia.	12637643
Inflammation, Fracture, Dental caries	Altered Intercellular Communication	The oral hygiene, caries incidence, clasps fractures were evaluated, it was registered the aspect of the acrylic resin of the base, and also the inflammation degrees of the oral mucousa.	12638298
AVP gene, Hyperprolactinemia, Hypopituitarism	Altered Intercellular Communication	A magnetic resonance image (MRI) showed an extensive hypothalamic and pituitary gland mass, and hormonal studies showed partial hypopituitarism and mild hyperprolactinemia without diabetes insipidus.	12638724
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Inflammation plays a significant contributory role in the pathogenesis of chronic heart failure (CHF).	12639217
Inflammation	Altered Intercellular Communication	These differences seem to reflect a greater degree of systemic inflammation linked to the presence of TA.	12639615
Inflammation, Budd-Chiari Syndrome	Altered Intercellular Communication	A common disease entity is suggested and the pathogenetic relevance of inflammation and venous outflow obstruction is discussed.	12639732
Refractory anemias, Pain Distress Question, Inflammation	Altered Intercellular Communication	In RA patients, after 3 months of MRQ treatment, there was a marked improvement in the pain and inflammation experienced by the patients as well as in the mobility of the affected joints.	12639750
Inflammation	Altered Intercellular Communication	Brain positron emission tomography initially showed a diffuse and multifocal cerebral hypometabolism with subsequent normalisation on her clinical recovery, which was consistent with the acute and reversible cerebral inflammation probably mediated by autoimmune mechanisms.	12640074
Communicable Diseases, Inflammation, Crohn Disease-like Reaction	Altered Intercellular Communication	In +/-40%, no infection occurred, but a Crohn's disease-like pattern of inflammation was noted.	12640307
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Asthma is a hyperresponsive airway disease that may involve inflammation responses.	12640628
Inflammation, Crohn Disease	Altered Intercellular Communication	Infliximab reduces mucosal inflammation in some, but not all, patients with Crohn's disease.	12641520
Herpes Zoster Ophthalmicus, Inflammatory abnormality of the eye	Altered Intercellular Communication	To determine the prognostic value of nasociliary skin lesions (Hutchinson's sign) for ocular inflammation and corneal sensory denervation in acute herpes zoster ophthalmicus.	12644941
Herpes Zoster Ophthalmicus, Inflammatory abnormality of the eye, Denervation	Altered Intercellular Communication	Hutchinson's sign was a powerful predictor of ocular inflammation and corneal denervation in herpes zoster ophthalmicus [relative risks: 3.35 (CI 95%: 1.82-6.15) and 4.02 (CI 95%:1.55-10.42), respectively].	12644941
Herpes zoster disease, Inflammatory abnormality of the eye	Altered Intercellular Communication	The manifestation of herpes zoster skin lesions at the dermatomes of both nasociliary branches was invariably associated with the development of ocular inflammation.	12644941
Inflammation, Empyema	Altered Intercellular Communication	These findings suggest that S. aureus-activated PMC extend PMN life span by modulating Bcl-xL and Bak gene expression and active caspases activity during acute inflammation and empyema.	12645855
Infection, Obesity	Altered Intercellular Communication	A wide range of environmental factors, including smoking, infections, and obesity, genetic factors, and the declining function of sex hormones may contribute to systemic low-grade inflammatory activity in older individuals.	12645876
Inflammation, Cell body of neuron, "Alzheimers Disease", Data types - Address, senile	Altered Intercellular Communication	beta-Amyloid peptide (A beta), a major component of senile plaques, the formation of which is characteristic of Alzheimer's disease (AD), is believed to induce inflammation of the brain mediated by microglia, leading to neuronal cell loss.	12646202
Inflammation, Transmural, Ulcerative Colitis, Granuloma	Altered Intercellular Communication	Whereas the inflammation in UC is confined to the mucosa/submucosa, CD is considered a transmural disease with characteristic lymphoid aggregates with or without epithelioid granulomas in the subserosa.	12647212
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Prominence of lymphatic capillaries could also be observed in areas where fibrosis replaced chronic inflammation.	12647212
Kidney Failure, Chronic, Inflammation, CDISC Integrated Basic Data Structure Dataset	Altered Intercellular Communication	These findings suggested that lymph-vessel proliferation in IBDs may be triggered by chronic inflammation irrespective of its organization and is maintained in fibrotic end-stage disease.	12647212
ARCN1 gene, Airway structure	Altered Intercellular Communication	Around 50% of the cost of COPD to the healthcare system was for prescription medication, including symptomatic medication and treatment for underlying airway inflammation.	12647943
Acute inflammation	Altered Intercellular Communication	Primary posterior capsulotomy should be performed in preschool and uncooperative children and in eyes expected to have relatively high postoperative inflammation.	12648639
Inflammation, Restenosis	Altered Intercellular Communication	Pre- and postintervention CRP levels were associated with restenosis after PTA of the distal popliteal and tibioperoneal arteries, which indicates that inflammation plays a crucial role in the pathophysiology of this process.	12649419
Airway structure	Altered Intercellular Communication	Exhaled breath condensate (EBC) is a rapidly expanding area of research to study airway inflammation through the detection of volatile and non-volatile substances in the airways.	12651772
Inflammation, Herpesviridae Infections	Altered Intercellular Communication	We conclude that stress-related alterations in hemostasis and inflammation are not necessarily linked to one particular herpesvirus infection but rather to an increase in aggregated seropositivity to herpesvirus infections.	12651986
Inflammation, Dental caries	Altered Intercellular Communication	The results suggest a relationship between caries and systemic parameters of inflammation.	12652044
Colorectal, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is a disease of unknown etiology characterized by chronic and superficial inflammation of colorectum.	12653068
Inflammation, Ulceration, CTCAE, Pathologic	Altered Intercellular Communication	Inflammation and ulceration have been described as pathologic damage associated with NSAID.	12653075
Airway structure, Asthma	Altered Intercellular Communication	Cytokines production by T helper lymphocytes (Th cells), which orchestrate the interplay of the different cells involved in airway inflammation of asthma, may be reflected in peripheral blood.	12653164
Malignant Neoplasms, Hypercalcemia	Altered Intercellular Communication	Parathyroid hormone-related peptide (PTH-rP) was associated with the syndrome of hypercalcaemia of malignancy.	12653746
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Liver inflammation and fibrosis were scored as 0 (none), 1 (mild), 2 (moderate) or 3 (severe) using biopsy specimens.	12653888
Inflammation, Congestive heart failure	Altered Intercellular Communication	Additional epidemiological investigations are warranted to confirm the contribution of inflammation to the pathogenesis of CHF in the general population.	12654604
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The potential role of systemic inflammation in chronic obstructive pulmonary disease.	12654609
Inflammation, Injury of cardiac valve	Altered Intercellular Communication	Low-grade systemic inflammation was present in participants with moderate to severe airflow obstruction and was associated with increased risk of cardiac injury.	12654609
Weight Gain, Inflammation	Altered Intercellular Communication	Association of body mass index, body fat, and weight gain with inflammation markers among rural residents in Japan.	12655163
Weight Gain, Inflammation, Obesity, Atherosclerosis	Altered Intercellular Communication	Because obesity is thought to play a key role in atherosclerosis through the low-grade chronic inflammation, the present study was designed to investigate associations of body mass index (BMI), body fat, and weight gain with optimized inflammation markers in 1,053 residents who were 40 years of age and older from a rural community (total population = 3,940 in 2000) in Japan.	12655163
Pulpitis	Altered Intercellular Communication	Following processing for light microscope analysis, the number of odontoblasts, pulp inflammation, and repair was recorded.	12656512
Pulpitis	Altered Intercellular Communication	Pulp inflammation was not influenced by RDT in the present study.	12656512
Inflammation, Heart failure, Kidney Failure	Altered Intercellular Communication	Two patients, more than 60-years-old, had developed global cardiac insufficiency with predominant left insufficiency, with physical alteration and biological inflammation.	12657441
Crohn Disease, Inflammation	Altered Intercellular Communication	Cutaneous metastatic Crohn's disease is a granulomatous inflammation of the skin that is noncontiguous to the gastrointestinal tract.	12657443
Inflammation	Altered Intercellular Communication	The degree of inflammation was determined by the intensity of aqueous flare measured with a laser flare cell meter every 2 hours from 11:00 to 17:00 hours for 2 days.	12657832
Primary sclerosing cholangitis, Inflammation, Fibrosis Assessment, Stenosis	Altered Intercellular Communication	Many patients with LPSP have distal CBD fibrosis, strictures, and inflammation, features that overlap somewhat with primary sclerosing cholangitis (PSC).	12657928
Inflammation, Dysplasia, Muscle hypertrophy, Fibrosis Assessment, Metaplasia	Altered Intercellular Communication	The following features were evaluated: degree and composition of mucosal inflammation and deep (mural) inflammation, lymphoid nodules, metaplasia, dysplasia/neoplasia, fibrosis, muscular hypertrophy, Rokitansky-Aschoff sinuses, and cholesterolosis.	12657928
Inflammation	Altered Intercellular Communication	LPSP gallbladders received the highest scores for deep inflammation of all groups, and 35% of LPSP gallbladders showed transmural chronic cholecystitis.	12657928
Inflammation	Altered Intercellular Communication	Mucosal inflammation in LPSP gallbladders correlated significantly with the presence of inflammation in the extrapancreatic portion of the CBD.	12657928
Inflammation, FAM126A gene	Altered Intercellular Communication	It was found that the 8-OHdG level in non-tumourous liver tissue was significantly higher than in HCC tissue (P = 0.006), and this was correlated with the degree of inflammation.	12658805
Inflammation, Gastrointestinal mucositis	Altered Intercellular Communication	These differences were not significant, but patients treated with chlorhexidine-based product seemed to have more problems with inflammation of the oral mucous membranes, resulting in an elevated mucositis score and a CRP increase.	12660125
Inflammation	Altered Intercellular Communication	Fortunately, histological tests only found inflammatory cells attesting that the mass was due to an inflammation of this area.	12660599
Inflammation, caruncle	Altered Intercellular Communication	Inflammation is one of the different processes that may increase the size of the caruncle, but sometimes, only histopathology can provide conclusive evidence.	12660599
Inflammation, Vegetation, Valvular stenosis, Calcified (qualifier), Endocarditis	Altered Intercellular Communication	We used quantitative image analysis to compare valvular fibrosis, calcifications, vegetations, inflammation, and vascularization due to Q fever endocarditis with that due to non-Q fever endocarditis and valvular degeneration.	12660924
Calcified (qualifier), Fibrosis Assessment, Inflammation, Endocarditis	Altered Intercellular Communication	Histologically, Q fever endocarditis was characterized by significant fibrosis and calcifications, slight inflammation and vascularization, and small or absent vegetations.	12660924
Inflammation, Cerebrovascular amyloidosis	Altered Intercellular Communication	The specimens showed an evidence of cerebrovascular amyloidosis, but no inflammation.	12661104
Pachymeningitis, Inflammation, Cholangitis	Altered Intercellular Communication	In view of the absence of angitis in the parenchymal and pial blood vessels, despite the presence of pachymeningitis, the cortical and bridging veins which drained into the venous sinuses, were likely involved in inflammation.	12661104
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation in asthma is not measured routinely in clinical practice.	12661997
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Heat Loss	Altered Intercellular Communication	In chronic obstructive pulmonary disease (COPD) there is decreased vascularity of the bronchi and inflammation of the airways that may have opposite effects on the regulation of heat loss.	12661998
ARCN1 gene, Airway structure	Altered Intercellular Communication	Exhaled air temperature increase (delta(e) T) was measured in 23 patients with moderate COPD (18 male, mean age +/- SEM 70 +/- 1 yrs; forced expiratory volume in one second (FEV1) 45 +/- 3%, FEV1/forced vital capacity 54 +/- 4%) and 16 normal volunteers (64 +/- 4 yr) and compared to exhaled nitric oxide (eNO) and inflammatory cells in induced sputum as a marker of airway inflammation.	12661998
Inflammation, Insemination, Artificial, Homologous	Altered Intercellular Communication	In conclusion, the clonality of expanded T cells within the liver tissue during early clinical manifestation of untreated AIH indicated that autoantigen-specific T cells accumulate at the inflammation site.	12662302
Inflammation, Helicobacter pylori	Altered Intercellular Communication	Helicobacter pylori induces inflammation of gastric mucosa regulated by several interleukins.	12662377
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The observed association suggests that individuals with interleukin-8-251TT and interleukin-10-819TT, a combination presumably causing mild inflammation, have a higher probability of the continuing Helicobacter pylori infection, especially among current smokers.	12662377
Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Inter-individual variation in the severity of gastric inflammation may be important in determining the clinical outcome of an Helicobacter pylori infection and relate to polymorphisms in this region.	12662382
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	When considered singly, all the genes were associated with disease diagnosis, inflammation, and intestinal metaplasia.	12663641
Inflammation	Altered Intercellular Communication	When coexpressed by the same H pylori strain, cagA, s1 and m1 vacA, and babA2 work synergistically in worsening inflammation.	12663641
Inflammation, Inflammatory Myofibroblastic Tumor, Hypercalcemia	Altered Intercellular Communication	This report describes a patient with an inflammatory myofibroblastic tumour in soft tissue who developed an inflammatory reaction, hypercalcaemia, and a high serum concentration of 1,25 dihydroxyvitamin D. Serum concentrations of 25-hydroxyvitamin D, parathyroid hormone, and parathyroid hormone related protein were normal.	12663647
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Cyclooxygenases (COXs) mediate inflammation, immunomodulation, blood flow, apoptosis, and fever in various diseases of the brain.	12663931
Mycobacterium Infections, Inflammatory abnormality of the eye	Altered Intercellular Communication	Two mechanisms can be proposed as the origin of ocular inflammation: a local immune response or a direct choroidal mycobacterial infection.	12664378
Inflammation, Neoplasms, Multiple Myeloma, Hereditary, Amyloidosis, senile	Altered Intercellular Communication	Amyloidosis can be primary, secondary (chronic inflammation, multiple myeloma, tumour), senile or hereditary.	12664379
Communicable Diseases, Inflammatory abnormality of the eye	Altered Intercellular Communication	The severe ocular inflammation could be the result of a mixed mechanism including an infectious followed by a severe immune response against bacterial components.	12664381
Cataract, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	[Anterior chamber inflammation following cataract surgery in patients with non-insulin-dependent diabetes mellitus].	12664479
Inflammatory abnormality of the eye	Altered Intercellular Communication	The pathologic analysis showed epithelialization of the conjunctival button-hole and diffuse ocular inflammation, mucopurulent material, and fibrovascular membranes.	12665228
Inflammation	Altered Intercellular Communication	Relation of inflammation and benefit of statins after percutaneous coronary interventions.	12665489
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	It is characterized by an infiltration of lipid-laden macrophages and associated with variable degrees of inflammation and fibrosis.	12666307
Rhinitis	Altered Intercellular Communication	[Assessment of changes in the course of nasal and paranasal inflammation].	12666594
Inflammation, Helicobacter pylori	Altered Intercellular Communication	It was investigated the type of inflammation and the existence of Helicobacter pylori.	12666632
Inflammation, Dental Plaque	Altered Intercellular Communication	Mechanical plaque removal was found to be very effective in the control of gingival inflammation for most patients, but the supplement of toothpastes and mouthwashes with anti-plaque properties may benefit individuals with unperfected plaque control.	12666956
Inflammation	Altered Intercellular Communication	Direct contact of circulating blood with the synthetic surfaces of the CPB system may be the main cause of the systemic inflammation.	12667129
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	Statistical analysis revealed that: (1) At the initial visit, there were no significant differences in the severity and activity of inflammation, atrophy and intestinal metaplasia between the biopsy specimens from the antrum and body respectively in both groups.	12667379
Inflammation	Altered Intercellular Communication	(2) The severity and activity of inflammation in both the antrum and body were markedly reduced after H. pylori eradication (P = 0.000).	12667379
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	The FA group showed obvious improvement of the gastric mucosal lesions with more patients displaying lesions reversed or stable atrophy and inflammation (P = 0.04), reversed intestinal metaplasia (P = 0.06) at the end of follow-up, and reversed displasia (P = 0.017) at 12 months.	12667380
Inflammation, MS gene	Altered Intercellular Communication	In multiple sclerosis (MS), an impaired apoptotic deletion of activated CNS-specific immune cells, leading to their pathogenic persistence, has been suggested to maintain chronic brain inflammation.	12667663
Airway structure	Altered Intercellular Communication	They are associated with increased airway inflammation and oxidative stress.	12668789
ARCN1 gene, Inflammation	Altered Intercellular Communication	Non-invasive markers of inflammation and oxidative stress are increased during an infective exacerbation of COPD and only slowly recover after treatment with antibiotics.	12668789
ARCN1 gene, Inflammation	Altered Intercellular Communication	These results suggest that RNS may be involved in the reversible component of inflammation in COPD that is suppressed by steroids.	12668791
Respiration Disorders	Altered Intercellular Communication	Aspirin (ASA)-exacerbated respiratory disease (AERD) is characterized by aggressive inflammation of the respiratory tract and often requires topical and/or systemic corticosteroids to maintain partial control of this disease.	12669898
Gastrointestinal mucositis	Altered Intercellular Communication	Mucositis is an acute inflammation of the oral mucosa because of radiotherapy and/or chemotherapy.	12671696
Colitis	Altered Intercellular Communication	In the CE group, there was a significantly better correlation between the endoscopic assessment of degree (P = 0.0002) and extent (89% vs. 52%; P < 0.0001) of colonic inflammation and the histopathologic findings compared with the conventional colonoscopy group.	12671882
Refractory anemias, Inflammation, Destruction of tissue	Altered Intercellular Communication	Perforin positive cells may participate in the acute phase of RA by maintaining and perpetuating inflammation and contributing to tissue destruction.	12672182
Inflammation, Atherosclerosis	Altered Intercellular Communication	Formation of nitric oxide-derived oxidants may serve as a mechanism linking inflammation to development of atherosclerosis.	12672736
Alopecia, Fibrosis Assessment, Hair follicle structure	Altered Intercellular Communication	The mechanisms by which smoking causes hair loss are multifactorial and are probably related to effects of cigarette smoke on the microvasculature of the dermal hair papilla, smoke genotoxicants causing damage to DNA of the hair follicle, smoke-induced imbalance in the follicular protease/antiprotease systems controlling tissue remodeling during the hair growth cycle, pro-oxidant effects of smoking leading to the release of pro-inflammatory cytokines resulting in follicular micro-inflammation and fibrosis and finally increased hydroxylation of oestradiol as well as inhibition of the enzyme aromatase creating a relative hypo-oestrogenic state.	12673073
Inflammation	Altered Intercellular Communication	The main goal of the analysis was to determine whether exercise type was associated with systemic markers of inflammation.	12673139
Lymphoid nodule, Inflammation	Altered Intercellular Communication	Chronic inflammation (P< 0.0001) and lymphoid follicle numbers ( P < 0.0005) were also significantly decreased after the eradication.	12673426
Gingivitis, Cardiobacterium (genus), Congenital heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	It was previously shown that children with congenital heart disease (CHD) harbored Hemophilus, Actinobacillus, Cardiobacter, Eikenella, and Kingella (HACEK) microbes to a greater extent and had more severe gingival inflammation than a normal group of children.	12673436
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	The purpose of this study was to determine if HACEK microbes are more prevalent in children with CHD than in normal children when there is no difference in gingival inflammation.	12673436
Cyanosis, Gingivitis, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	This study found that the greater extent of specific HACEK microbes harbored by children with CHD is not associated with cyanosis or the degree of gingival inflammation.	12673436
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Formalin fixed paraffin embedded biopsy specimens from mild, moderate, and severe active inflammation of ulcerative colitis and from normal colonic tissue were observed.	12674803
Inflammation	Altered Intercellular Communication	The number of TUNEL positive epithelial cells were significantly higher in moderate and severe active inflammation compared to each other and to normal (p < 0.0001).	12674803
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	These results demonstrate that there is a strong correlation between the histological activity of ulcerative colitis and elevated crypt epithelial cell turnover, although the alterations in proliferation develop in the earlier stages of inflammation.	12674803
Inflammation, effusion	Altered Intercellular Communication	The concentration of cystatin F in benign effusions correlated significantly with diagnostic parameters and inflammation (total protein; lactate dehydrogenase; C-reactive protein).	12675521
Inflammation, Asthma	Altered Intercellular Communication	Circadian variations in serum eosinophil cationic protein, and serum and urine eosinophil protein X. Biochemical evaluation of inflammation may be a useful adjunct to measures of pulmonary function and symptoms in children with asthma.	12675759
Narcolepsy, Sleep Disorders	Altered Intercellular Communication	Narcolepsy is a sleep disorder caused by defective hypocretin (orexin) neurotransmission.	12676332
Inflammation	Altered Intercellular Communication	Inflammation can result in DNA damage related to its severity, the cellular antioxidant capacity, and the integrity of DNA repair mechanisms.	12676777
Inflammation	Altered Intercellular Communication	Interleukin-1 (IL-1) polymorphisms have been shown to be important mediators of inflammation, while glutathione S-transferase GST T1 and GST M1 polymorphisms are believed to affect cellular antioxidant capacity.	12676777
Inflammation	Altered Intercellular Communication	Thirteen of these 14 patients showed inflammation in at least one vascular region.	12677302
Inflammation, Traumatic injury, Cerebral Ischemia	Altered Intercellular Communication	Interferon regulatory factor-1 (IRF-1), a transcription factor that controls the expression of genes related to inflammation and injury, may be involved in the mechanisms of cerebral ischemia.	12677441
Inflammation, Neoplasms	Altered Intercellular Communication	To ascertain whether the absorption of L-lysine diatrizoate, a sodium-free salt of the contrast-giving diatrizoic acid from the gastrointestinal tract is increased by surgery, inflammation, and neoplasia.	12677458
Neoplasms	Altered Intercellular Communication	However, inflammatory conditions and neoplasms involving the large bowel increase the uptake of the contrast medium from the intestine.	12677458
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Cytokines are essential mediators of the intestinal inflammation during active episodes of inflammatory bowel disease (IBD).	12678335
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Compared to controls, histological examination showed significant differences in signs of chronic and acute inflammation in UC (P < 0.01) and CD (P < 0.02), revealing a high correlation between clinical disease activity and histological scoring (r2 = 0.92, P < 0.005).	12678335
Inflammatory Bowel Diseases, Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	The expression of both IL-12 and IL-17 mRNA is induced in active UC and CD and may thus be involved in sustaining the intestinal inflammation in IBD.	12678335
Inflammation, Neoplasms	Altered Intercellular Communication	Both protein synthesis and amino acid transport are enhanced in most tumor cells, but their metabolism is less affected in inflammation.	12679396
Inflammation, Fracture	Altered Intercellular Communication	Minor complications included pin track inflammation/infection in 36 of 98 (37%) fractures.	12679684
Inflammation, Specimen Type - Fistula, Specimen Source Codes - Abscess	Altered Intercellular Communication	After the management of local inflammation and abscess, the patient was operated for primary repair of the fistula.	12679955
Inflammation, Arthritis Pain, Dysmenorrhea	Altered Intercellular Communication	Valdecoxib, a cyclooxygenase-2 inhibitor, is a benzenesulfonamide prescribed for arthritis pain and inflammation, and dysmenorrhea.	12680487
Pain Distress Question, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Markers of vitamin B(6) status are associated with disease activity and severity, synovial burden, and pain in patients with rheumatoid arthritis, raising the possibility that impaired vitamin B(6) status in these patients is a result of inflammation.	12681455
Inflammation, Pancreatic Polypeptide	Altered Intercellular Communication	Although a proportion of this neocortical pathology may be secondary to WM inflammation, the extent of the changes suggests that, especially in patients with PP MS, an independent neurodegenerative process also is active.	12682324
Tumor necrosis, Acute cardiac pulmonary edema	Altered Intercellular Communication	To determine whether acute cardiogenic pulmonary edema is associated with damage to the alveolocapillary barrier, as evidenced by increased leakage of surfactant specific proteins into the circulation, to document the duration of alveolocapillary barrier damage in this setting, and to explore the role of pulmonary parenchymal inflammation by determining if circulating tumor necrosis factor-alpha is increased after acute cardiogenic pulmonary edema.	12682473
Tumor necrosis, Pneumonitis, Congenital Abnormality	Altered Intercellular Communication	Although the initial increase in plasma surfactant protein-A and -B may represent hydrostatic stress failure of the alveolocapillary barrier, the prolonged elevation, when hemodynamic abnormalities have resolved, and the delayed elevation of tumor necrosis factor-alpha are consistent with pulmonary parenchymal inflammation, which may further damage the alveolocapillary barrier.	12682473
Glomerulonephritis, Membranoproliferative, Kidney Diseases, Thickening of glomerular capillary wall	Altered Intercellular Communication	Idiopathic membranoproliferative glomer-ulonephritis (MPGN) is a relatively uncommon cause of progressive renal disease characterized by immune complex deposition resulting in mesangial proliferation and endocapillary inflammation with capillary wall thickening.	12682679
Ozena (disorder), Inflammation	Altered Intercellular Communication	Primary atrophic rhinitis is a chronic inflammation of the nasal mucosa characterized by atrophy of the mucous and bony tissue of the turbinates and by a thick, dense secretion, which quickly forms a characteristically fetid-smelling, greenish crust.	12682843
Inflammation, Leukocytosis, Fever, CTCAE, Chest Pain, Symptoms, Have Shortness of Breath question, Weight decreased	Altered Intercellular Communication	Whereas the prevalence of thoracic symptoms such as shortness of breath, cough, or chest pain was similar in both groups (MLA, 165 [69.3%]; NLMT, 41 [69.5%]; p = 0.98), systemic symptoms, including fever, night sweats, or weight loss (MLA, 110 [49.8%]; NLMT, 17 [29.3%]; p < 0.01), and signs of inflammation, such as c-reactive protein, erythrocyte sedimentation rate, and leukocytosis (MLA, 202 [85.6%]; NLMT, 34 [57.6%]; p < 0.001), were significantly more common in MLA.	12683542
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by an accelerated decline in lung function and progressive airway inflammation.	12684248
ARCN1 gene, Airway structure	Altered Intercellular Communication	Bacteria have been isolated from the lower airway of stable COPD patients, and airway inflammation has been related to bacterial load and type.	12684248
Airway structure, Colonization	Altered Intercellular Communication	The relationship between bacterial colonization, airway inflammation, and lung function decline remains uncertain.	12684248
Airway structure	Altered Intercellular Communication	Rising airway bacterial load and species changes are associated with greater airway inflammation and accelerated decline in FEV1.	12684248
Airway structure, ARCN1 gene	Altered Intercellular Communication	We investigated the impact of cigarette smoking on airway inflammation in COPD patients.	12684293
Pleurisy, Pleural Effusion, Malignant	Altered Intercellular Communication	Repeated thoracenteses may cause pleural inflammation and induce local release of proinflammatory cytokine as TNF-alpha, which may subsequently enhance the release of PAI-1 and lead to fibrin formation in malignant effusion.	12684310
Pneumonitis	Altered Intercellular Communication	We concluded that inhaled (1-->3)-beta-D-glucan may be involved in the mechanisms of pulmonary inflammation in patients with AEP.	12684329
Inflammation, Carcinogenesis	Altered Intercellular Communication	Macrophage inflammatory protein (MIP-3alpha) is a CC chemokine that attracts immature dendritic cells and lymphocytes and is thought to play a role in the pathogenesis of inflammation and carcinogenesis.	12684696
Inflammation, Dysplasia, Carcinoma, Squamous cell carcinoma, Lymphoma, Nevus, conjunctiva, Conjunctival intraepithelial neoplasia, Squamous metaplasia	Altered Intercellular Communication	Diagnoses of the conjunctival lesions, in decreasing order of frequency, were conjunctival intraepithelial neoplasia (dysplasia, carcinoma in situ), squamous cell carcinoma, squamous metaplasia, nevus, lymphoma and inflammation.	12685195
Inflammation, Sinus histiocytosis	Altered Intercellular Communication	Histopathology showed fibroconnective tissue with chronic inflammation and marked lymph node sinus histiocytosis.	12685200
Inflammation, Purpura	Altered Intercellular Communication	Increased intestinal permeability and activity of skin purpura correlated with severity of inflammation in the duodenal mucosa.	12685393
Inflammation, Myelitis, Disease	Altered Intercellular Communication	We recently reported the occurrence of myelitis in patients with atopic disorders and its pathology to be eosinophilic inflammation.	12686395
Inflammation, Chlamydia, Atherosclerosis	Altered Intercellular Communication	Detection of Chlamydia pneumoniae in peripheral blood mononuclear cells: correlation with inflammation and atherosclerosis in haemodialysis patients.	12686665
HD Term Type, Inflammation, Atherosclerosis	Altered Intercellular Communication	We attempted to accurately estimate C.pneumoniae prevalence and to examine whether C.pneumoniae is associated with atherosclerosis and inflammation in haemodialysis (HD) patients.	12686665
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation was assessed by C-reactive protein and serum amyloid A and atherosclerosis was evaluated from clinical and laboratory data.	12686665
Fibrous, Inflammation	Altered Intercellular Communication	All lesions were characterized microscopically by polypoid projections of fibrous tissue covered by epithelium and demonstrating varying degrees of inflammation.	12686857
Upper Respiratory Infections	Altered Intercellular Communication	The main sign of disease was respiratory inflammation.	12687280
Inflammation, Sore to touch, Swelling	Altered Intercellular Communication	Ultrasonography showed signs of inflammation in 94 joints, while clinical assessment revealed tenderness and/or swelling in 64 joints.	12687537
Inflammation	Altered Intercellular Communication	Signs of inflammation were more frequently detected with ultrasound than with clinical examination.	12687537
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	In conclusion, female alcoholics seems to progress to liver cirrhosis earlier because of high daily alcohol intake adjusted to body weight, poor nutritional condition and inflammation caused by endotoxin.	12687725
Inflammation	Altered Intercellular Communication	It has been postulated that splanchnic ischemia, as manifested by gastric hypercarbia, helps to trigger excessive systemic inflammation, which has been linked to the development of adverse postoperative outcome.	12690437
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Mast cells play an important role in tissue inflammation, fibrosis and remodelling.	12690558
Inflammation, Autoimmune Pancreatitis	Altered Intercellular Communication	Autoimmune pancreatitis is a unique clinical entity proposed recently, and is sometimes associated with inflammation of other organs.	12692053
Autoimmune Pancreatitis	Altered Intercellular Communication	The development of the specific inflammations in extensive organs as well as the pancreas in patients with autoimmune pancreatitis strongly suggests a close relationship between autoimmune pancreatitis and multifocal fibrosclerosis.	12692053
Inflammation	Altered Intercellular Communication	The transbronchial lung biopsy specimen showed granulomatous inflammation and numerous lipoid-laden macrophages in the alveolar spaces.	12692999
Inflammation, Drug Dependence	Altered Intercellular Communication	Any sinonasal inflammation involving the midline that persists or remains refractory to treatment may be the first manifestation of potentially lethal drug addiction.	12693654
Inflammation, Traumatic injury, Neoplasms, Congenital Abnormality	Altered Intercellular Communication	Stenosis of the nasolacrimal drainage system is a relatively frequent complication of acute or chronic inflammation, trauma, tumor, or congenital malformation.	12693657
malignant disease, Inflammation, Disease	Altered Intercellular Communication	The function of YKL-40 in cancer diseases is unknown, but it is a growth factor of connective tissue cells and probably has a role in inflammation and remodeling of the extracellular matrix, a process also involved in metastatic malignant diseases.	12694127
Microalbuminuria, Inflammation, Lymphoma, Non-Hodgkin	Altered Intercellular Communication	Mediators of inflammation correlate with microalbuminuria in patients with non-Hodgkin's lymphoma.	12694249
Microalbuminuria, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	This is the first study that shows a direct correlation between microalbuminuria and proinflammatory cytokines in malignancies, indicating a pathogenic relationship between inflammation and glomerular leakage of albumin.	12694249
HD Term Type, Inflammation	Altered Intercellular Communication	These results indicate that in HD patients, the presence of low-grade inflammation decreases the efficiency of cardiovascular therapeutic interventions and participates in the persistence of cardiovascular hemodynamic overload.	12694318
Granulomatous inflammation	Altered Intercellular Communication	Polymerase chain reaction based detection of Mycobacterium tuberculosis in tissues showing granulomatous inflammation without demonstrable acid-fast bacilli.	12694493
Granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	Cutaneous tuberculosis represents a significant proportion in specimens showing granulomatous inflammation.	12694493
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	However, scalp biopsy specimens from the frontal hair margin showed perifollicular fibrosis and lymphocytic inflammation.	12695141
Arterial Stiffness, Inflammation	Altered Intercellular Communication	Chronic inflammation may impair vascular function and lead to an increase of arterial stiffness, an important determinant of cardiovascular risk.	12695151
Inflammation	Altered Intercellular Communication	Gut biopsy samples were available in 18 AS and 10 patients with uSpA, these samples were screened for the presence of inflammation.	12695160
Inflammation, immunoglobulin A	Altered Intercellular Communication	No significant differences in ASCA IgA levels were noted between patients with SpA with and without histological gut inflammation.	12695160
Inflammation, immunoglobulin A	Altered Intercellular Communication	No correlation between the presence of subclinical bowel inflammation and ASCA IgA levels was noted.	12695160
Inflammation, Atherosclerosis	Altered Intercellular Communication	There are several risk factors that ARMD shares with atherosclerosis, and these diseases may have similar pathogenic mechanisms that involve inflammation.	12695244
Inflammation, Chlamydia, Cardiovascular Diseases	Altered Intercellular Communication	Chlamydia pneumoniae, a prokaryotic pathogen that causes chronic inflammation is now emerging as a risk factor in the development of cardiovascular diseases.	12695244
Orbital Pseudotumor	Altered Intercellular Communication	Idiopathic orbital inflammation: distribution, clinical features, and treatment outcome.	12695246
Orbital Pseudotumor	Altered Intercellular Communication	A 10-year retrospective review of patients with idiopathic orbital inflammation treated at one institution.	12695246
Dacryoadenitis, Myositis, CTCAE 5.0, Orbital Pseudotumor	Altered Intercellular Communication	Diagnoses were isolated dacryoadenitis (n = 21), isolated myositis (n = 19), concurrent dacryoadenitis and myositis (n = 5), orbital apex syndrome (n = 6), and idiopathic inflammation involving the preseptal region, supraorbital region, sclera, Tenon capsule, orbital fat, or optic nerve (n = 14).	12695246
Inflammation	Altered Intercellular Communication	Neutrophil (PMN) apoptosis regulates PMN functional longevity and is integral to the resolution of inflammation.	12697081
Gingivitis	Altered Intercellular Communication	When weighing recommendations for oral hygiene home care, clinicians should consider that an essential oil-containing mouthrinse may be a useful adjunct in patients with gingival inflammation.	12699051
Inflammation	Altered Intercellular Communication	Following the recovery of the patients from the acute inflammation of the heart, PBMC no longer exhibited a proliferation response to the FAD-peptide.	12699430
Pneumonitis	Altered Intercellular Communication	Mice subjected to cecal ligation and puncture developed acute lung inflammation and showed VAP-1 not only in endothelial cells but also in inflammatory cells in perivascular areas at 72 h after the procedure.	12700900
Vasculitis, Leukocytoclastic, Cutaneous, Inflammation	Altered Intercellular Communication	The retro-orbital inflammation was histologically diagnosed as hypersensitivity vasculitis (HV).	12700924
Inflammation	Altered Intercellular Communication	A strong positive correlation was present between apoptosis and both inflammation and activity scores in infected antral mucosa.	12702040
Inflammation, Osteopenia	Altered Intercellular Communication	soft tissue inflammation but no bone loss, was selected.	12702106
Inflammation	Altered Intercellular Communication	Examination revealed nongranulomatous anterior-segment inflammation in the right eye greater than the left.	12703689
Inflammation, Complication Aspects	Altered Intercellular Communication	Follow-up examinations have shown a gradual decrease in the inflammation, with no ocular complications.	12703689
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	An association between aortic pulse wave velocity, blood pressure and chronic inflammation in ESRD patients on peritoneal dialysis.	12703883
Pain Distress Question, Inflammation	Altered Intercellular Communication	Care consisted of various forms of passive modalities to reduce pain and inflammation, as well as hip mobilization and tissue stretching.	12704314
Inflammation, Dysplasia, Adenomatous hyperplasia, Neoplasms, Endometriosis of uterus, Adenoma	Altered Intercellular Communication	In 36 percent of the patients the papillary specimens demonstrated acute or chronic inflammation, in 44 percent adenoma, including 5 percent with severe dysplasia, in 5 percent adenomatous hyperplasia and in 7 percent adenomyosis or other benign tumors (2%) were found.	12704445
Inflammation	Altered Intercellular Communication	Correlation between inflammatory activation and neuronal markers may suggest a link between inflammation and release of markers of neuronal clinical and subclinical injury.	12705643
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Only when such tertiary tissues are subjected to chronic inflammation, such as in some (but not all) autoimmune diseases, are naive T cells recruited to these sites.	12707342
Inflammation	Altered Intercellular Communication	Netilmycin in combination with Cefasolin was more effective for acute pyo-inflammatory diseases of lower extremities than a combination of Gentamycin with Cefasolin, it more rapidly resulted in reduction of clinical signs of inflammation, was better endured and more economical.	12708395
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Hence, the expression level of FcgammaRs on monocytic cells may influence inflammation in patients with rheumatoid arthritis (RA).	12709546
Inflammatory abnormality of the eye	Altered Intercellular Communication	Disease activity was defined according to the existence of ocular inflammation.	12712358
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	The development of quantitative methods to measure the degree of necrosis, inflammation and fibrosis in liver biopsies favored the knowledge of the natural course of liver fibrosis.	12712848
Inflammation, Clostridium, Emphysematous Cholecystitis	Altered Intercellular Communication	Emphysematous cholecystitis is a rare gallbladder pathology characterized by gas accumulation in the gallbladder wall as a result of severe inflammation, mostly caused by bacteria known as Clostridium species.	12712899
Inflammation, Chlamydia, Dermal - anatomy qualifier, Infection	Altered Intercellular Communication	Recently it has been pointed out that inflammation and infections caused by germs such as Chlamydia pneumoniae are independent cardiovascular risk factors for the general population, but information about these relationships in dialysis patients is scarce.	12713079
Inflammation, Chlamydia, Infection, Cardiovascular system	Altered Intercellular Communication	These data suggest that inflammation and the presence of Chlamydia pneumoniae infections are important predictors of cardiovascular death in patients on CAPD.	12713079
palladium, Inflammation	Altered Intercellular Communication	Instead, the results suggest that more attention should be given to inflammation and inadequate fluid removal as predictors of mortality in PD patients.	12713086
Inflammation, Ischemic	Altered Intercellular Communication	ET-1 may vasoconstrict microvessels and mediate inflammation in chronically ischaemic muscle.	12713784
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Biopsies of the skin lesions showed fibrosis without inflammation.	12713861
Alzheimers Disease", Inflammation, Angular	Altered Intercellular Communication	Progression of neuritic and Abeta pathology in the cerebral cortex during aging and Alzheimer disease is well known, but the chronology of the various types of lesions (Abeta deposition, amyloid formation, inflammation, ubiquitination, tangle formation) within a given area has not been fully elucidated.	12714113
Inflammation	Altered Intercellular Communication	Such changes may contribute to the worse prognosis of unstable patients with raised indices of inflammation.	12714832
Inflammation, Thrombocytosis, Malignant Neoplasms	Altered Intercellular Communication	Reactive thrombocytosis (RT) is occasionally observed in clinical situations including chronic inflammation and malignancy.	12714883
Inflammation	Altered Intercellular Communication	Billroth I or II reconstruction after distal gastrectomy often is associated with inflammation in the gastric remnant.	12715225
Nasal Polyps, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Research of Bernstein and Stoop showed the influence of inflammation of nasal mucosa on growth of nasal polyps.	12715352
neutrophilic, Inflammation	Altered Intercellular Communication	In the group of patients with both neutrophilic and eosinophilic polyps dominating bacterial flora included bacteria which usually are the cause of inflammation.	12715352
Inflammation, Carcinoma, Lymphadenitis, Hodgkin Disease, Lymphoma, Non-Hodgkin, Lymph Node Tuberculosis, Hyperplasia	Altered Intercellular Communication	FNAC diagnosis was found to be as follows: granulomatous inflammation 46 (40.35%), reactive hyperplasia 31 (27.19%), metastatic carcinoma 20 (17.54%), Non-Hodgkin's lymphoma 6(5.26%), tubercular lymphadenitis 4(3.51%), acute non-specific lymphadenitis 3(2.63%), Hodgkin's lymphoma 3(2.63%) and chronic non-specific lymphadenitis 1(0.88%).	12715640
Arthritis	Altered Intercellular Communication	uPA exerts potent arthritogenic properties and thus may be viewed as one of the essential mediators of joint inflammation.	12716448
Inflammation, Premenopause	Altered Intercellular Communication	Twenty of the women studied, who had no signs of inflammation as evidenced from vaginal wet smears, were pre-menopausal and 8 post-menopausal.	12716498
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	These findings suggest an association between glycemic control and systemic inflammation in people with established diabetes.	12716818
Inflammation	Altered Intercellular Communication	The inflammation factors decreased (P = 0.001), and albumin increased (P = 0.002).	12717087
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver fibrosis and mild inflammation persisted in 8 patients.	12717399
Inflammation	Altered Intercellular Communication	This phenomenon may be mediated by components of the pathogen itself or may occur secondary to immune events in chronic inflammation.	12719455
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is associated with atherosclerosis of coronary arteries.	12719858
Inflammation, Synovitis	Altered Intercellular Communication	Using MRI as the "gold standard," PD sonography with and without echo-enhancing contrast agent cannot reliably identify synovitis or distinguish synovial inflammation from effusion in the shoulder joint.	12719926
Inflammation, Calcinosis	Altered Intercellular Communication	Sepsis-related microvascular myocardial damage with giant cell inflammation and calcification.	12719978
Inflammation, Calcinosis	Altered Intercellular Communication	On postmortem examination, the findings were restricted to the heart and characterized by microvascular myocardial damage with giant cell inflammation and calcification.	12719978
Inflammation, Infection, Malignant Neoplasms	Altered Intercellular Communication	Infections and malignant tumor also were unlikely causes based upon the negative pleural fluid results and the negative pleural biopsy findings, except for nonspecific inflammation.	12720042
Communicable Diseases, Inflammation	Altered Intercellular Communication	The present observations suggest that infection and inflammation may be associated with the onset of PLE.	12720566
Nasal inflammation	Altered Intercellular Communication	Mometasone furoate nasal spray (MFNS, Nasonex, Schering, Kenilworth, NJ), an anti-inflammatory nasal corticosteroid, has been shown to be safe and effective in reducing the nasal inflammation of SAR.	12722964
Coughing, nasal itching, IL13 gene	Altered Intercellular Communication	Cough commonly occurs as a symptom of seasonal allergic rhinitis (SAR), an inflammatory condition of the nasal mucous membranes that results in rhinorrhea, nasal stuffiness/congestion, nasal itching, and sneezing.	12722964
Communicable Diseases, Electrocardiogram: myocardial infarction (finding), Inflammation, Neoplasms	Altered Intercellular Communication	Patients with h/o myocardial infarction (MI) in the preceding 1-month and evidence of infection, inflammation or neoplasm were excluded from the study.	12723647
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	H. pylori colonization, inflammation and activity were more severe in the Japanese and Thai populations than in the Chinese and Vietnamese populations and these scores were more antrum-predominant in the Thai and Vietnamese populations than in the Japanese and Chinese populations, with the most severe degree of atrophy and intestinal metaplasia occurring in the angulus region of the Japanese population.	12725322
Communicable Diseases, Inflammation	Altered Intercellular Communication	A case history of a patient with permanent pacemaker reports inaccurate diagnosis of inflammation at the site of operation wound and a protracted infection of pacemaker leads.	12728600
Inflammation, Vegetation	Altered Intercellular Communication	Inadequate therapy led to protracted inflammation with the leads fixed in the superior vena cava and the development of large vegetations in the right heart.	12728600
Inflammation	Altered Intercellular Communication	The histology of synovial tissue taken at arthroscopy showed acute inflammation and Erysipelothrix rhusiopathiae, identified with some difficulty, was isolated from the enrichment broth only.	12729059
Inflammation	Altered Intercellular Communication	The histological appearance is that of a benign chronic inflammation varying in severity and with metaplastic activity.	12729773
Inflammation	Altered Intercellular Communication	Resolution of inflammation/infection involves removal of neutrophils and other inflammatory cells by the induction of apoptosis.	12729991
Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	In conclusion, these results show that increased levels of Fas/Apo-1 from patients with SIRS is a mechanism which contribute to inflammatory response through accumulation of neutrophils at sites of inflammation/infection.	12729991
Atherosclerosis	Altered Intercellular Communication	Inflammation underlies both onset and perpetuation of atherosclerosis.	12730297
Inflammation, Crohn Disease, Colitis	Altered Intercellular Communication	Rho kinase blockade prevents inflammation via nuclear factor kappa B inhibition: evidence in Crohn's disease and experimental colitis.	12730857
Gastrointestinal inflammation	Altered Intercellular Communication	We investigated the role of RhoA and its downstream effector Rho kinase in intestinal inflammation.	12730857
Colitis	Altered Intercellular Communication	Oral administration of Y-27632 in rats significantly reduced the colonic inflammation.	12730857
Gastrointestinal inflammation	Altered Intercellular Communication	Our study provides the first evidence that Rho kinase activates I-kappa B kinase and, thus, nuclear factor kappa B, suggesting a key role of Rho kinase in inflammatory responses and intestinal inflammation.	12730857
Inflammatory disorder	Altered Intercellular Communication	In contrast, under inflammatory conditions, ADAM-10, expressed by perivascular macrophages, and ADAM-17, expressed by invading T cells, may actively contribute to the pathogenesis of inflammatory disorders of the CNS.	12730960
Guillain-Barre Syndrome, Familial, Guillain-Barre Syndrome, Immune-mediated neuropathy, Inflammation	Altered Intercellular Communication	Guillain-Barre syndrome (GBS) is an immune-mediated neuropathy, in which leukocytes and humoral components of the immune system proposedly initiate localized inflammation.	12730990
Inflammatory Bowel Diseases, Phlebitis, Intestinal Diseases	Altered Intercellular Communication	Inflammatory bowel disease (IBD) comprises a group of diseases of intestine characterized by chronic inflammation of the bowel with periods of exacerbation and remission.	12731216
Inflammation, Hemorrhage, Meckel Diverticulum, Intussusception, Neoplasms	Altered Intercellular Communication	In the Meckel's diverticulum, ectopic tissue or neoplasms are sometimes found, which may lead to intussusception, hemorrhage, or inflammation.	12731730
Inflammation, Chlamydia, Helicobacter pylori, atherosclerotic	Altered Intercellular Communication	Detection of Chlamydia pneumoniae but not of Helicobacter pylori in symptomatic atherosclerotic carotids associated with enhanced serum antibodies, inflammation and apoptosis rate.	12732399
Inflammation, Destruction of bile ducts, Autoimmune Chronic Hepatitis	Altered Intercellular Communication	Liver biopsy revealed chronic inflammation with lymphocytes and plasma cells in portal areas without destruction of bile ducts, suggesting autoimmune hepatitis.	12732893
Inflammation, Intraoperative, Obesity	Altered Intercellular Communication	Causes of the conversions were severe obesity (body mass index 62.5), uncontrolled intraoperative bleeding (HIV+), nondiagnostic tissue sampling (2 cases), perisplenic inflammation and perisplenic abscesses (3 cases).	12734679
Inflammation, Vascular System Injuries	Altered Intercellular Communication	Recently it has been suggested this technique is capable of detecting microvascular injury and inflammation because sonicated albumin microbubbles adhere to activated neutrophils and, in the presence of denuded or inflamed endothelium, they persist within the microvasculature rather than passing unimpeded, which results in profound slowing of their transit rates.	12735577
Myocarditis, Postoperative cognitive dysfunction	Altered Intercellular Communication	The technique has not previously been used during congenital heart surgery; however significant potential is suggested in this setting in which myocardial inflammation may contribute to postoperative myocardial dysfunction, a leading cause of morbidity and mortality.	12735577
Bronchitis	Altered Intercellular Communication	As primary efficacy variable, eosinophil cationic protein (ECP) in induced sputum as direct measurement of bronchial inflammation was assessed before and after treatment.	12736396
Inflammation, Edema of bone marrow	Altered Intercellular Communication	Bursitis, adventitious bursa, localized soft-tissue inflammation, and bone marrow edema in tibial stumps: the contribution of magnetic resonance imaging to the diagnosis and management of mechanical stress complications.	12736896
Inflammation, Bursitis, Synovial bursa	Altered Intercellular Communication	MRI identified 13 sites of bursitis (adventitious bursa, 11; synovial bursitis, 2) and 5 localized areas of soft tissue inflammation.	12736896
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	The chronic inflammation of the salivary glands in Sjogren's syndrome may be a self-sustaining process promoting autoantibody production in the target organ, possibly contributing to increased serum levels of autoantibodies.	12737325
Inflammation, "Alzheimers Disease", Data types - Address, PHEX gene, Exfoliation Syndrome	Altered Intercellular Communication	The occurrence of inflammation with accompanying amyloid formation in pseudoexfoliation syndrome (PEX) resembles other inflammation-associated amyloidoses such as Alzheimer's disease (AD).	12737497
Cataract	Altered Intercellular Communication	The presence of Abeta and inflammation-associated proteins in aqueous from cataract cases without detectable PEX raises the possibility that these proteins may reflect early amyloid-related changes in the eye.	12737497
Inflammation	Altered Intercellular Communication	We are exploring the possibility that carbohydrate components on H. pylori contribute to the persistent inflammation through interactions with leukocyte-endothelial adhesion molecules of the host.	12738381
Helicobacter pylori, Ulceration, CTCAE, Gastritis	Altered Intercellular Communication	Helicobacter pylori is an important pathogen in gastroduodenal inflammation and ulceration.	12738388
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The study showed enhanced expression of interleukin (IL) -8, IL-10 and interferon-gamma (IFN-gamma) in H. pylori infection and a significant association was found between these cytokines and the following parameters: bacteria load, chronic inflammation and activity.	12738388
Inflammation, Hypereosinophilia	Altered Intercellular Communication	About 2 weeks after surgical intervention the patient developed a multiorgan disorder (gastroenteric, neuromuscular and renal involvement) associated with hypereosinophilia and with increased levels of the markers of inflammation.	12739429
Inflammatory abnormality of the eye, Behcet Syndrome, Vasculitis, CTCAE	Altered Intercellular Communication	Behcet's disease is a chronic systemic vasculitis with unknown etiology characterized by recurrent oral and genital ulcerations, ocular inflammation,having manifestations related to the skin and joints.	12739840
ARCN1 gene, Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Platinum-based, leukocyte-depleting chemotherapy does not alter induced sputum markers of neutrophilic inflammation in COPD patients with unresectable non-small cell lung cancer.	12740514
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Neutrophilic inflammation is a major feature of chronic obstructive pulmonary disease (COPD), and several novel therapies aim at the suppression of neutrophils in COPD.	12740514
Inflammation, Pulmonary Emphysema, Gout, Macular degeneration	Altered Intercellular Communication	To examine the relationship of 2 diseases associated with systemic inflammatory response, emphysema and gout, and selected markers of systemic inflammation with the 10-year incidence of age-related maculopathy.	12742845
Inflammation, Atherosclerosis, Diabetes Mellitus	Altered Intercellular Communication	Considerable evidence implicates the proinflammatory cytokine CD40 ligand (CD40L) in atherosclerosis and accumulating data link type 1 and 2 diabetes, conditions associated with accelerated atherosclerosis, to inflammation.	12742991
Autoimmune Diseases, Communicable Diseases, Chlamydia, Inflammation	Altered Intercellular Communication	Synergistic effect of persistent Chlamydia pneumoniae infection, autoimmunity, and inflammation on coronary risk.	12743003
Inflammation, Atherosclerosis, Autoimmune Diseases, Chronic infectious disease, Chlamydia, Communicable Diseases	Altered Intercellular Communication	Given the role of chronic infections, autoimmunity, and inflammation in atherosclerosis, we studied the joint effect of chronic Chlamydia pneumoniae infection, persistently elevated human heat-shock protein 60 (hHsp60) antibodies, and C-reactive protein (CRP) on coronary risk.	12743003
Quadriceps weakness, Inflammation, Proximal weakness, Facial Paresis	Altered Intercellular Communication	Atypical features with this same mutation were marked quadriceps weakness in five patients, proximal weakness only in two patients, facial weakness in three patients, and a muscle biopsy showing perivascular inflammation in one patient.	12743242
Asthma, Eosinophilic inflammation	Altered Intercellular Communication	Effects of suplatast tosilate on allergic eosinophilic airway inflammation in patients with mild asthma.	12743558
Asthma	Altered Intercellular Communication	Suplatast tosilate appears to inhibit allergic airway inflammation mediated by T(H)2-type cytokine and to improve clinical symptoms in patients with mild asthma.	12743558
Inflammation, Atrophic, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Biopsy specimens were obtained from the gastric antrum and body to assess grade of inflammation and atrophy and histologic evidence of H. pylori infection.	12743772
Inflammation, Duodenal Ulcer	Altered Intercellular Communication	Histopathological findings of inflammation and activity grade in both gastric and duodenal ulcers were more favorable in patients with successful eradication than in those with unsuccessful eradication.	12743773
Inflammation	Altered Intercellular Communication	Histopathological findings were also improved with regard to inflammation and activity (neutrophils) in patients in whom H. pylori eradication was successful.	12743773
Inflammation, Granuloma	Altered Intercellular Communication	Biopsy specimens demonstrated acute and chronic inflammation with multiple small, noncaseating granulomas at the level of the foveolar isthmi-the junction between the pits and the glands.	12743778
Suppuration, Inflammation, Pneumonia	Altered Intercellular Communication	The distinctive morphological features of today's caseous pneumonia were as follows: a great extent of lesion, an unrestrained progression of a process, a predominance of an alterative-and-exudative component of tuberculous inflammation, a rapid decay and suppuration of caseous masses, no differentiation of caseous and pneumonic foci, and suppressed cellular reactions of tissue immunity.	12744061
Communicable Diseases, Malignant Neoplasms, Certified Midwife	Altered Intercellular Communication	Although several case reports discuss CM in the setting of bowel malignancy, our case illustrates that non-malignant bowel inflammation may be a sufficient source for the infection.	12745042
Synovitis, Refractory anemias, Damage, Erosion of bone, Arthritis	Altered Intercellular Communication	This study shows that there is a predilection for both synovitis and bone erosion formation on the radial side of the MCP joints in early RA, and that joint inflammation appears to drive the inherent tendency for bone damage on the radial side of joints.	12746894
Refractory anemias, Arthritis	Altered Intercellular Communication	Together, these data underscore the crucial role of synovial macrophages in RA joint inflammation and indicate that selective elimination of these cells through FcgammaRI-directed immunotoxins could be a novel approach to the treatment of RA.	12746896
Bone Marrow	Altered Intercellular Communication	Both patterns of bone marrow inflammation (focal and diffuse) were observed in equal frequencies in early and late disease (17% and 42% versus 26% and 43%, respectively; P NS).	12746910
Sacroiliitis, Enthesitis	Altered Intercellular Communication	Sacroiliac enthesitis is not a special feature of early sacroiliac inflammation.	12746910
Inflammation, Tissue Adhesions	Altered Intercellular Communication	During surgery, intense inflammation with multiple adhesions throughout the peritoneal cavity and around the liver were found.	12746999
Arthritis, Chronic arthritis	Altered Intercellular Communication	Our study suggests that also a Sindbis virus infection may be associated both to an acute joint inflammation as a part of Pogosta disease or chronic arthritis.	12747277
Synoviocytes, Inflammation	Altered Intercellular Communication	Membrane attack complex formation in deficient membrane bound CD59 may also exacerbate synovial cell injury and inflammation.	12747280
Inflammation, Malnutrition	Altered Intercellular Communication	An increased neutrophil count is strongly associated with, and reduced lymphocyte count associated less strongly with, many surrogates of both malnutrition and inflammation.	12748351
Inflammation, Pulmonary Emphysema, asthma chronic	Altered Intercellular Communication	Most pneumologists assume that chronic asthma and emphysema associated with smoking differ both in their etiology and type of inflammation.	12749805
Inflammation, Unspecified visual loss	Altered Intercellular Communication	This can be associated with complications that include inflammation, visual loss, and hypotony.	12750086
Inflammation	Altered Intercellular Communication	Laboratory tests subsequently revealed evidence of systemic inflammation, and radiologic studies showed extensive mediastinal and cervical adenopathy.	12750114
Enterocolitis, Neutropenic, Leukopenia	Altered Intercellular Communication	Neutropenic enterocolitis: is it possible to break vicious circle between neutropenia and the bowel wall inflammation by surgery?	12750931
Enterocolitis, Neutropenic, Leukopenia	Altered Intercellular Communication	Neutropenic enterocolitis is a devastating bowel wall inflammation in patients with protracted neutropenia.	12750931
Leukopenia	Altered Intercellular Communication	Retrospective analysis of the long-term follow-up of our patient suggests that defunctioning the colon by ileostomy breaks the vicious circle between neutropenia and bowel wall inflammation, and an early surgical intervention could be considered as an adjunctive approach to the conservative management of persistent cases.	12750931
Inflammation, Complication Aspects	Altered Intercellular Communication	Chronic inflammation of the middle ear is the most frequent cause of otogenic complications.	12751163
ARCN1 gene, Nasal inflammation	Altered Intercellular Communication	In the present study, we have examined whether or not COPD is associated with any nasal inflammation.	12752555
ARCN1 gene, Nasal inflammation	Altered Intercellular Communication	We conclude that COPD is not associated with any marked nasal inflammation.	12752555
Gastritis, Ear Inflammation	Altered Intercellular Communication	The highest scores for both mononuclear inflammation and activity of gastritis were significantly associated with cagA status (p = 0.036 antrum and p = 0.02 corpus).	12752735
Nutritional Deficiency, Inflammation, Depression, CTCAE	Altered Intercellular Communication	To examine the association between muscle strength and total and cause-specific mortality and the plausible contributing factors to this association, such as presence of diseases commonly underlying mortality, inflammation, nutritional deficiency, physical inactivity, smoking, and depression.	12752838
Cessation of life, Inflammation, Depression, CTCAE, Chronic disease	Altered Intercellular Communication	Presence of chronic diseases commonly underlying death or the mechanisms behind decline in muscle strength in chronic disease, such as inflammation, poor nutritional status, disuse, and depression, all of which are independent predictors of mortality, did not explain the association.	12752838
Degenerative polyarthritis, Arthritis	Altered Intercellular Communication	Because the late stages of osteoarthritis involve joint inflammation with a mild increase in local temperature, skin surface temperature might reasonably be expected to serve as a proxy measure of osteoarthritis pain.	12752882
Inflammation	Altered Intercellular Communication	Forty-seven liver biopsies from patients with chronic HBV with varying degrees of inflammation (ALT values) were selected.	12753333
Airway structure, Coughing	Altered Intercellular Communication	We aimed to examine airway inflammation and bronchial responsiveness in patients with chronic non-productive cough responsive to anti-asthma therapy.	12753531
Coughing, Chronic cough, Airway structure	Altered Intercellular Communication	These findings suggest that patients with chronic non-productive cough responsive to anti-asthma therapy characteristically have eosinophilic airway inflammation, which may play an important role in the development of chronic cough.	12753531
Airway structure	Altered Intercellular Communication	Furthermore, the evaluation of not only bronchial responsiveness but also airway inflammation by examination of induced sputum may be useful for diagnosis and deciding on therapeutic strategies.	12753531
Coronary Stenosis, Angina, Unstable, Inflammation	Altered Intercellular Communication	Association between complex coronary artery stenosis and unstable angina and the extent of plaque inflammation.	12753875
Inflammation	Altered Intercellular Communication	We evaluated the association between qualitative assessment of coronary stenoses and plaque inflammation determined by immunohistochemistry.	12753875
atherosclerotic	Altered Intercellular Communication	The extent of atherosclerotic inflammation within each coronary lesion was determined by the percentage of immunopositive macrophages per total tissue area (including smooth muscle cells) and the number of T lymphocytes per mm(2).	12753875
Coronary Lesion Complexity, Angina, Unstable, Plaque, Atherosclerotic	Altered Intercellular Communication	The extent of atherosclerotic plaque inflammation is associated with angiographic grading of coronary lesion complexity and unstable angina.	12753875
Inflammation, Axonal loss	Altered Intercellular Communication	Sural nerve biopsies showed multifocal axonal loss in all patients, with epineurial perivascular inflammation affecting small calibre vessels in three.	12754358
Inflammation, Hyperplasia, Ulcer	Altered Intercellular Communication	Mucosal ulcers, hyperplasia and chronic inflammation were frequently found, while polyps were uncommon.	12754574
Malignant tumor of colon, Inflammation, Hyperplasia, Ulcer	Altered Intercellular Communication	MC is also associated with other risk factors for cancer of colon, such as hyperplasia, mucosal ulcers and chronic inflammation.	12754574
Inflammation, Communicable Diseases, Lymphadenopathy, Autoimmune Disorder, CTCAE, Hyperthyroidism	Altered Intercellular Communication	Thirteen patients (31%) with lymphadenopathy in the neck and head area had developed localized chronic inflammation (chronic sialoadenitis=4, chronic tonsillitis=3, infectious epidermal cyst=2) or an autoimmune disorder (hyperthyroidism=2 and bronchial asthma=2).	12754626
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Cytokines are the primary mediators of inflammation and also influence matrix metalloproteinase expression, both of which are important in development of abdominal aortic aneurysm (AAA).	12756345
Vitreoretinal Area, Inflammation	Altered Intercellular Communication	Intravitreal dexamethasone effectively reduces postoperative inflammation after vitreoretinal surgery.	12757090
Inflammatory abnormality of the eye	Altered Intercellular Communication	Corticosteroids remain the mainstay for control of ocular inflammation after vitreous surgery.	12757090
Inflammation, Vitreous strands	Altered Intercellular Communication	Intravitreal dexamethasone significantly alleviates postoperative inflammation after vitreous surgery and is a useful adjunct.	12757090
Hepatosplenomegaly, Pancytopenia, Anemia, Inflammation of perianal region	Altered Intercellular Communication	The patient was hospitalized for malaise, progressive pancytopenia, hepatosplenomegaly, progressive anemia, and perianal inflammation.	12757096
Inflammation, Eosinophilic Granuloma	Altered Intercellular Communication	Gastroduodenoscopy showed normal jejunal mucosa although histology revealed flattened villi, crypt proliferation, acute inflammation, and eosinophilic granulomata.	12757218
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	This suggests that increased erythropoiesis and subclinical inflammation could be part of the metabolic syndrome in elderly Koreans.	12757983
Inflammation, Neuronal loss in central nervous system	Altered Intercellular Communication	MR spectroscopy (MRS) indicated neuronal loss, inflammation, and metabolically compromised tissue; magnetisation transfer imaging (MTI) showed an increase in whole brain lesion load.	12759301
Inflammation, destruction joint	Altered Intercellular Communication	These data support a role of HC gp-39 in the local autoimmune response that leads to chronic inflammation and joint destruction.	12759455
Inflammation, Macular Edema, Cystoid, Polycystic Ovary Syndrome	Altered Intercellular Communication	Acrylic lenses appeared to provide the best overall results when evaluated for post-operative inflammation, PCO rates, visual acuity, and cystoid macular edema (CME) (compared to PMMA, silicone, and heparin coated PMMA).	12759839
Pharyngitis	Altered Intercellular Communication	Five cases with nasopharyngeal inflammation and neck lymphatic node proliferation were demonstrated to be EBV DNA negative.	12759983
Inflammation	Altered Intercellular Communication	TiN surfaces showed a significant reduction of the presence of bacteria, and this fact could probably be important in the decrease of the inflammation of the peri-implant soft tissues.	12760451
Inflammation, Primary Neoplasm, Malignant Neoplasms	Altered Intercellular Communication	Specific pathologic diagnosis was rendered for the 10 percutaneous biopsies that were not confirmed by surgical biopsy: five biopsies matched known primary malignancies, consistent with metastases; four biopsies revealed primary tumors, and one biopsy revealed chronic inflammation (nine true-positives and one true-negative).	12760920
Kidney Failure, Chronic, Inflammation, Malnutrition	Altered Intercellular Communication	Plasma pentosidine is associated with inflammation and malnutrition in end-stage renal disease patients starting on dialysis therapy.	12761263
Kidney Failure, Chronic, Inflammation, Malnutrition	Altered Intercellular Communication	The present study shows that an elevated plasma pentosidine content in ESRD patients is significantly associated with both inflammation and malnutrition and confirms that low residual renal function and high age further contribute to an increased plasma pentosidine content.	12761263
Inflammation, Failure (biologic function)	Altered Intercellular Communication	The remaining procedures did not provide a diagnosis because of failure to obtain appropriate specimen (11 patients), findings consistent with non-specific inflammation (2 patients) or uneventful surgical complication requiring termination of the procedure (1 patient).	12761679
Angina, Unstable	Altered Intercellular Communication	Carotid plaque inflammation in a patient with unstable angina.	12762276
Inflammation, Dental Plaque	Altered Intercellular Communication	Coronary instability has been associated with multifocal plaque activation in the coronary circulation and in remote vascular districts, suggesting a systemic cause of instability, possibly inflammation.	12762276
Inflammation	Altered Intercellular Communication	Magnetic resonance imaging offers a great potential for the detection of plaque inflammation.	12762276
Inflammation, Dental Plaque, Edema	Altered Intercellular Communication	Magnetic resonance imaging of the plaque before and after contrast enhancement by gadolinium-DTPA showed the following signs of inflammation: an increased vessel wall thickness, an increased triple inversion recovery-fast spin-echo signal intensity indicative of tissue edema, and a homogeneous plaque contrast enhancement indicative of an increased capillary permeability and neovasculature.	12762276
Inflammation, Dental Plaque, Cerebrovascular accident	Altered Intercellular Communication	In the present case report, the simultaneous presence of coronary instability and a carotid plaque with magnetic resonance features suggestive of inflammation, which was probably responsible for the stroke complicating cardiac surgery, may indicate a multifocal plaque instability.	12762276
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Chronic ulcerative colitis is not a uniform disease entity because the clinical pattern and disease characteristics differ on the basis of the anatomic location of the inflammation.	12763418
Dysplasia, Myocarditis, Fibrosis Assessment, Myofiber disarray, Infarction, Hypertrophy, Left bundle branch structure, senile	Altered Intercellular Communication	Overall, microscopic abnormalities included myocyte hypertrophy (100%), endocardial (96%) and myocardial (93%) fibrosis, myocyte disarray (79%) and vacuolization (60%), endocardial inflammation (48%), arterial thickening (46%), dilated venules (28%), arterial dysplasia (16%), left bundle branch tissue (12%), infarction (2%), endocardial (1%) and myocardial (<1%) calcium, and amyloid (1%; senile type in all three).	12763554
Inflammation, Vascular Alterations, Array, Fibrosis Assessment, Hypertrophy	Altered Intercellular Communication	The most common microscopic features were hypertrophy, disarray, fibrosis, inflammation and vascular alterations.	12763554
Inflammation, Depression, CTCAE, Atherosclerosis, Coronary heart disease	Altered Intercellular Communication	Because atherosclerosis is an inflammatory process, depression could increase the risk of coronary heart disease by inducing or promoting inflammation.	12764206
Inflammation, Depression, CTCAE	Altered Intercellular Communication	In this group, low-grade systemic inflammation could represent a mechanism linking depression to cardiovascular risk.	12764206
Cardiovascular Diseases	Altered Intercellular Communication	Participants included a total of 6149 individuals aged 17 to 39 years who were free of cardiovascular diseases and chronic inflammatory conditions.	12764206
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	Uptake of 18fluorodeoxyglucose in the cystic fibrosis lung: a measure of lung inflammation?	12765432
Alcohol abuse	Altered Intercellular Communication	Chronic alcohol abuse causes severe and persistent alterations in the hormonal regulatory systems of electrolyte and water balance.	12766631
Inflammation, Melkersson-Rosenthal Syndrome	Altered Intercellular Communication	Histochemical analysis showed inflammation of the lymphoid plasmacellular type with mucipolysaccharidoid deposition typical of Melkersson-Rosenthal syndrome.	12766825
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Moderately elevated serum C-reactive protein (CRP) concentration is a systemic marker of inflammation and a documented risk factor for cardiovascular disease in otherwise healthy persons.	12767953
Communicable Diseases, Inflammation	Altered Intercellular Communication	Inflammation, infection and cardiovascular events in chronic hemodialysis patients: a prospective study.	12768072
Inflammation, ciliary vesicle	Altered Intercellular Communication	Inflammation is a potent risk factor for CV disease in the general population.	12768072
Communicable Diseases, Chlamydia, Inflammation	Altered Intercellular Communication	Recent evidence suggests infection, particularly with agents such as Chlamydia pneumoniae (C.pneumoniae) and Helicobacter pylori (H.pylori), as a source of sustained inflammation.	12768072
Aneurysm, Inflammation	Altered Intercellular Communication	At surgery, the aneurysm was found to be surrounded by a thickened-leptomeninges, which histologically showed the presence of cysticercous with dense inflammation.	12768515
Granulomatous inflammation, Chronic inflammation	Altered Intercellular Communication	Amyloid appeared as dark-blue to purple clumps of acellular material on Diff-Quik stain, accompanied with chronic inflammatory cell infiltrates and multinucleated giant cells, simulating granulomatous inflammation.	12768639
Inflammation	Altered Intercellular Communication	MRI and CT revealed inflammation in the temporal bone and locally thickened dura mater with obvious enhancement as a band in the petrous apex and nearby tentorium cerebellum.	12768703
Inflammation, Autoimmune reaction	Altered Intercellular Communication	The attraction of leukocytes to tissues is essential for inflammation and the beginning of autoimmune reaction.	12770795
Inflammation	Altered Intercellular Communication	He was demonstrated to have granulomatous inflammation of the lung, as well as of the gastrointestinal tract.	12772229
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	All 134 patients tested for Helicobacter pylori infection were infected, and 65/66 (98%) had inflammation of both the antrum and the corpus.	12772798
Inflammation, Metabolic Syndrome X, Atherosclerosis	Altered Intercellular Communication	Inflammation has been suggested as a risk factor for the development of atherosclerosis, while some components of metabolic syndrome X have been related to inflammatory markers.	12773138
Inflammation	Altered Intercellular Communication	These data demonstrate a significant decrease in plasma adiponectin in low-grade chronic inflammation, and suggest that there is an important linkage between inflammation/adipose tIssue/atherosclerosis.	12773138
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation is infrequently observed in muscle biopsy.	12773872
Inflammation, Sarcoidosis	Altered Intercellular Communication	In sarcoidosis, muscle biopsy showed a granulomatous inflammation of varying intensity, which was generally associated with mononuclear inflammatory cells.	12773872
Lymphoma, Non-Hodgkin, Inflammation	Altered Intercellular Communication	This case suggests that there was a relationship between the development of non-Hodgkin's lymphoma and the presence of chronic inflammation in the pulse generator pocket.	12774929
Airway structure, Bronchial Hyperreactivity	Altered Intercellular Communication	Bronchial hyperresponsiveness (BHR) is characteristic of asthmatic airways, is induced by airway inflammation, and is reduced by inhaled corticosteroids (ICS).	12775860
Inflammation	Altered Intercellular Communication	Many authors have proposed a role for inflammation in the pathophysiology of CRVO in young patients.	12778350
Inflammation, Hyperhomocysteinemia, Coronary Arteriosclerosis	Altered Intercellular Communication	These findings suggest that inflammation and hyperhomocysteinemia may be important mechanisms by which smoking promotes atherosclerotic disease.	12779299
Inflammation, Neoplasms	Altered Intercellular Communication	Overstaging was more common in patients who had undergone a previous excision and in tumours with peritumoral inflammation and desmoplastic reaction.	12780886
Inflammation, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	The inflammation grade of the liver, stage of fibrosis and degree of chronic hepatitis were recorded and were compared with fibrotic indexes.	12781034
Inflammation, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Among 2600 chronic hepatitis patients, every fibrotic index had a significant correlation with the inflammation grade, fibrosis staging and the degree of chronic hepatitis (P < 0.01).	12781034
Inflammation, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Serum fibrosis indexes are fairly well correlated with the inflammation grade of the liver, fibrosis staging and the degree of chronic hepatitis.	12781034
Choroiditis	Altered Intercellular Communication	Angiographic examination disclosed choroidal inflammation at the macula and a breakdown of the blood retinal barrier.	12782171
Dystonia Disorders	Altered Intercellular Communication	In patients with pharmacologic or degenerative dopaminergic neurotransmission disorders, cholinergic excess may induce this peculiar type of dystonia.	12782913
Necrotizing granulomatous inflammation, Perivascular inflammation	Altered Intercellular Communication	Orbital biopsy demonstrated chronic granulomatous inflammation with perivasculitis.	12782922
Temporal Arteritis, Orbital Pseudotumor	Altered Intercellular Communication	This unusual presentation of orbital inflammation in association with temporal arteritis demonstrates that pathologic findings of temporal arteritis may be clinically nonspecific and that external beam radiation may be an effective therapy in this setting.	12782922
Infarction, Inflammation, IKZF3 gene, Arteritis	Altered Intercellular Communication	At the time of late recurrent AION, there were no systemic symptoms or elevations in acute phase reactants to signal active arteritis, yet temporal artery biopsy disclosed dramatic inflammation, forcing the presumption that the infarct was arteritic.	12782923
Inflammation	Altered Intercellular Communication	Brain and meningeal biopsy disclosed a necrotizing granulomatous inflammation of small and medium-sized subarachnoid vessels.	12782929
Inflammation, Traumatic injury, Neoplasms	Altered Intercellular Communication	Radiographs were judged as essential for reading of MRI studies more often for trauma, infection/inflammation and tumors than for degenerative and miscellaneous/normal diagnoses (chi(2)=60.95, df=16, P<0.0001).	12783223
Inflammation, Traumatic injury, Neoplasms	Altered Intercellular Communication	The clinical and MRI diagnoses were the same or partially concordant significantly more often for tumors than for trauma, infection/inflammation and degenerative conditions, while in the miscellaneous/normal group they were different in 64% of cases.	12783223
Primary sclerosing cholangitis, Fibrosis Assessment, Cholestatic liver disease	Altered Intercellular Communication	Primary sclerosing cholangitis (PSC) and cystic fibrosis (CF) are both slowly progressive cholestatic liver diseases characterized by fibro-obliterative inflammation of the biliary tract.	12783301
Inflammation, Thrombosis	Altered Intercellular Communication	Inflammation at a glance: erythrocyte adhesiveness/aggregation test to reveal the presence of inflammation in people with atherothrombosis.	12783631
Inflammation, Thrombosis	Altered Intercellular Communication	The erythrocyte adhesiveness/aggregation test is a new biomarker to detect low-grade inflammation in patients with atherothrombosis.	12783631
Communicable Diseases, Helicobacter pylori, Inflammation	Altered Intercellular Communication	The active inflammation of antral mucosae in the patients with BRG that without Helicobacter pylori (Hp) infection was more severe than that in the patients with physiologic DGR that without Hp infection significantly (P < 0.05).	12783700
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	To explore the role of H4/ICOS function in the inflammation of rheumatoid joints, lymphokine production by SF CD4+ T cells co-stimulated by H4/ICOS was assayed.	12784384
Giant Cell Arteritis, Vasculitis, GCA gene, Temporal Arteritis	Altered Intercellular Communication	To determine the frequency, characteristics, and short term outcome of patients who have biopsy-proven giant cell arteritis (GCA) but no local symptoms that can be attributed to vasculitis inflammation [silent temporal arteritis (TA)] throughout the pretreatment course of the disease or an observational period lasting at least 2 months.	12784402
Inflammation, Arthropathy	Altered Intercellular Communication	Adhesion molecules and their functions are important in arthropathies not only because their evaluation can allow us to identify the degree of inflammation and to predict its evolution, but also because pharmacological control of their expression could have important therapeutic implications.	12784911
Communicable Diseases, Tumor necrosis, Inflammation	Altered Intercellular Communication	Helicobacter pylori (HP) related inflammation is mediated by tumour necrosis factor alpha (TNFalpha), which "in vitro" increases epithelial apoptosis in response to infection.	12784913
vascular inflammations, Bipolar Disorder	Altered Intercellular Communication	Lack of association between depressive symptoms and markers of immune and vascular inflammation in middle-aged men and women.	12785468
vascular inflammations, Depression, CTCAE, Coronary heart disease	Altered Intercellular Communication	Disturbed immune activity and vascular inflammation are associated both with clinical depression and coronary atherogenesis, and may constitute a mechanism through which depression contributes to coronary heart disease.	12785468
vascular inflammations, Bipolar Disorder	Altered Intercellular Communication	If this is the case, then non-clinical depressive symptoms and psychological distress should be associated with immune activation and vascular inflammation.	12785468
Inflammation, Colitis	Altered Intercellular Communication	Repifermin (keratinocyte growth factor-2) has been shown to reduce inflammation in animal models of colitis.	12786629
Inflammation, Temporomandibular Joint	Altered Intercellular Communication	To evaluate the relationship between the volume of joint effusion (JE), determined by T2-weighted magnetic resonance imaging (MRI), and microscopic findings of synovial inflammation in internal derangement of the temporomandibular joint (TMJ).	12789161
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	To explore the role of human herpesvirus-8 (HHV-8) in the pathogenesis of uveitis and other forms of ocular inflammation.	12789595
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	Serum antibody titers to HHV-8 were measured in 76 patients with uveitis from various causes and other types of ocular inflammation in either the acute phase, the convalescent phase, or both.	12789595
Intraocular inflammation	Altered Intercellular Communication	The role of HHV-8 in the pathogenesis of intraocular inflammation appears to be limited.	12789595
Multiple Myeloma, Myanmar, Malignant Neoplasms	Altered Intercellular Communication	Monoclonal Gammopathy (MG) in multiple myeloma (MM) is an established association but its occurrence in nonmyelomatous malignancies and other inflammatory conditions is still a subject of research.	12789724
Inflammation, prostatitis	Altered Intercellular Communication	The Prostant is effective and safe in the treatment of chronic prostatitis, especially on those cases whose symptom and inflammation in prostatic fluid are not too serious.	12791192
Inflammation, Primary malignant neoplasm, Digestive System Disorders, Pain Distress Question	Altered Intercellular Communication	Prognostic value of dietary intake and inflammation on survival in patients with advanced cancer: relationship with performance status, pain, and digestive disorders.	12791502
Eye pain, Inflammation	Altered Intercellular Communication	All patients experienced loss of ocular pain and inflammation, rapid reepithelialization of the ocular surface, and marked improvement in visual acuity.	12792468
Intravascular Route of Drug Administration, Granulomatous inflammation	Altered Intercellular Communication	Eosinophils were identified in 4 biopsy specimens, intravascular thrombi in 10 (22%) specimens, and granulomatous inflammation in 1 specimen.	12792923
Inflammation, human parvovirus B19 virus, Enterovirus, Myositis, Doctor of Chiropractic, Myocarditis, CTCAE 5.0, Dilated Cardiomyopathy Pathway	Altered Intercellular Communication	Although enteroviruses have long been considered the most common cause of inflammatory heart muscle diseases, parvovirus B19 (PVB19) is emerging as a new and important candidate for myocarditis and dilated cardiomyopathy with inflammation (DCMi) and without inflammation (DCM).	12792925
Inflammation, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	In patients with resolved myocarditis, no PVB19 DNA was detected; in patients with no inflammation and controls, prevalence was only 4% and 7%, respectively.	12792925
Inflammation, Common Cold, Language spoken	Altered Intercellular Communication	The most prevalent symptoms were colds and troubled sleep and the least prevalent were inflammation of the throat and poor spoken language.	12795075
Inflammation, Weight decreased, Diarrhea	Altered Intercellular Communication	In rats with TNBS-induced colitis, oral RDP58 therapy reduced weight loss and diarrhoea and improved macroscopic and histological inflammation scores.	12795464
Gastrointestinal inflammation	Altered Intercellular Communication	Theoretically, oral iron supplementation may even be harmful, because iron may reinforce intestinal inflammation by catalysing production of reactive oxygen species.	12795468
Crohn Disease, gastrointestinal, Anemia, Inflammation	Altered Intercellular Communication	The Crohn Disease Activity Index, gastrointestinal complaints and blood samples for antioxidant status, anaemia, inflammation and iron absorption were investigated on day 1 and day 8.	12795468
Inflammation, Heart failure	Altered Intercellular Communication	However, it is not known whether inflammation plays a role in the time-course of heart failure (HF) in this clinical setting.	12796768
Granulomatous inflammation	Altered Intercellular Communication	Bladder biopsies showed granulomatous inflammation and subsequent urine cultures grew Mycobacterium bovis.	12799151
Lymphoma, Pseudolymphoma, Chronic inflammation	Altered Intercellular Communication	Final diagnoses included 17 lymphomas, 18 chronic inflammations, 4 reactive lymphoid hyperplasias, and 4 atypical lymphoid infiltrates.	12799255
Lymphoma, Pseudolymphoma, Chronic inflammation	Altered Intercellular Communication	Molecular evidence of clonality was identified in 88% (15 of 17) of lymphomas, 39% (7 of 18) of chronic inflammations, and 50% (4 of 8) of reactive lymphoid hyperplasias and atypical lymphoid infiltrates.	12799255
Coughing, Asthma, Upper Respiratory Infections	Altered Intercellular Communication	In addition influences of intensity of respiratory tract inflammation, gender, type of asthma, and disease period on the effect of Bakumondo-to on the cough sensitivity were examined.	12799501
Upper Respiratory Infections	Altered Intercellular Communication	Although respiratory tract inflammation was not significantly improved, number of eosinophils in peripheral blood, sputum eosinophil ratio and ECP level in the serum were remarkably decreased more than the half.	12799501
Airway structure, Asthma	Altered Intercellular Communication	And Bakumondo-to was more effective in asthmatic subjects with severe airway inflammation.	12799501
Inflammation, Cranial Nerve Injuries	Altered Intercellular Communication	The traditional treatment of choice has been operative repair, which can present a significant technical challenge owing to the reoperative neck inflammation and potential cranial nerve injuries.	12799730
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Many people with the metabolic syndrome have a low-grade inflammation, which may increase their risk for future adverse events.	12801619
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	A better understanding of the potential consequences of the high prevalence of low-grade inflammation among people with the metabolic syndrome is needed.	12801619
Inflammation, With intensity, At risk of infection	Altered Intercellular Communication	In the 44 patients with disk infection, MR imaging criteria with good to excellent sensitivity included presence of paraspinal or epidural inflammation (n = 43, 97.7% sensitivity), disk enhancement (n = 42, 95.4% sensitivity), hyperintensity or fluid-equivalent disk signal intensity on T2-weighted MR images (n = 41, 93.2% sensitivity), and erosion or destruction of at least one vertebral endplate (n = 37, 84.1% sensitivity).	12802004
Inflammation, septic	Altered Intercellular Communication	HLA-DR as a marker for increased risk for systemic inflammation and septic complications after cardiac surgery.	12802492
Inflammation	Altered Intercellular Communication	For better long-term results, repair should be performed by the referral surgeon at a stage without coexisting active inflammation.	12802669
Cranial nerve palsies, Inflammation, Coccidioidal meningitis, Failure (biologic function)	Altered Intercellular Communication	A previously healthy 47-year-old man with coccidioidal meningitis had fluconazole treatment failure and developed severe symptoms, multiple cranial nerve palsies, and brain-stem inflammation visible on magnetic resonance imaging (MRI).	12802765
Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	Monocyte chemoattractant protein-1 (MCP-1) is a chemokine that is produced mainly by tubular epithelial cells in kidney and contributes to renal interstitial inflammation and fibrosis.	12803507
Inflammation, Hypertension, CTCAE, Anemia, Kimura Disease	Altered Intercellular Communication	The activity of Kimura's disease is closely related refractory hypertension, suggesting that inflammation may be involved in refractory hypertension and anemia in a dialytic patient with Kimura's disease.	12803515
Diffuse Axonal Injury, neuron death, Nerve Degeneration	Altered Intercellular Communication	Although the tPA-plasmin cascade promotes neurodegeneration in excitotoxin-induced neuronal death, in inflammatory conditions with BBB disruption it has been demonstrated to have a protective role in removing fibrin, which exacerbates axonal injury.	12805124
Inflammation, Brain Diseases, Musculoskeletal Pain	Altered Intercellular Communication	In addition, PTHrP appears to affect vascular growth and to be a mediator of inflammation in rheumatic and brain disorders.	12805493
Inflammation, Carcinogenesis	Altered Intercellular Communication	These epithelial changes presumably induced by chronic inflammation due to the reflux of intestinal contents and bile stasis may be responsible for the carcinogenesis.	12806201
Crohn Disease, Abnormality, Gastrointestinal inflammation	Altered Intercellular Communication	Subclinical intestinal inflammation: an inherited abnormality in Crohn's disease relatives?	12806605
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	We assessed the possible presence, prevalence, and inheritance pattern of subclinical intestinal inflammation in apparently healthy relatives of patients with Crohn's disease.	12806605
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	A total of 49 patients with Crohn's disease, 16 spouses, and 151 (58%) of 260 available first-degree relatives underwent a test for intestinal inflammation (fecal calprotectin concentration).	12806605
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	There is a high prevalence of subclinical intestinal inflammation in first-degree relatives of patients with Crohn's disease that conforms best to an additive inheritance pattern.	12806605
Inflammation, Basal cell hyperplasia	Altered Intercellular Communication	Basal cell hyperplasia in needle biopsy tissue was typically focal and associated with inflammation, which was usually lymphocytic, in 84% of cases.	12808066
Inflammation, Basal cell hyperplasia	Altered Intercellular Communication	The presence of inflammation in the majority of basal cell hyperplasia foci suggests that peripheral zone basal cell hyperplasia in untreated patients may represent a stereotyped response to injury such as that sustained because of inflammation.	12808066
Inflammation, Hyperemia	Altered Intercellular Communication	Endoscopic examination found focal linear hyperemia on the mucosa of the stomach antrum, and endoscopic biopsy confirmed eosinophilic inflammation of the mucosa and submucosa of the stomach, terminal ileum, and cecum.	12808334
Inflammation, Infection by Trichuris trichiura, Ascites	Altered Intercellular Communication	She is the first case of eosinophilic inflammation of the gastrointestinal tract and ascites associated with trichuriasis in the stomach.	12808334
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	A simple and reproducible scoring system of inflammation and fibrosis of the gallbladder is proposed.	12808565
Inflammation	Altered Intercellular Communication	Three numbers refer to mild, moderate, or severe degrees of chronic inflammation and activity, with a final score that results from adding both values.	12808565
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Randomized studies have shown an improvement in the oxidative capacity of the skeletal muscles, to an attenuation of chronic inflammation, correction of endothelial dysfunction, and to normalization of the frequently pathological ventilation under effort.	12808800
Neurologic Deficits	Altered Intercellular Communication	These results suggest that detection of the 14-3-3 protein in the CSF provides a marker for severe inflammation-induced extensive damage of the central nervous system tissues responsible for poor therapeutic responses and irreversible neurological deficits in MS.	12809994
Inflammation, Rheumatoid Arthritis, Polyarthritis	Altered Intercellular Communication	Magnetic resonance imaging in the assessment of synovial inflammation of the hindfoot in patients with rheumatoid arthritis and other polyarthritis.	12810213
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Synovial tissue (ST) from end stage destructive rheumatoid arthritis (RA) and arthroscopic biopsies obtained during active inflammation might exhibit different characteristics.	12810425
Granulomatous inflammation	Altered Intercellular Communication	To evaluate the added diagnostic value of gallium-67 scintigraphy in patients with WG with suspected granulomatous inflammation in the paranasal and chest regions.	12810430
Inflammation, Infection caused by Helicobacter pylori, Hypergastrinemia (finding)	Altered Intercellular Communication	Hypochlorhydria, hypergastrinaemia, inflammation and Helicobacter pylori infection, dose and duration of omeprazole treatment may separately, or in combination, influence the proliferation of enterochromaffin-like (ECL) cells and parietal cell changes in gastric mucosa.	12811309
Hypergastrinemia (finding), Inflammatory disease of mucous membrane	Altered Intercellular Communication	In patients without intrinsic acid hypersecretion and hypergastrinaemia significant proliferation of ECL cells is not an issue irrespective of gastric mucosal inflammation, omeprazole dose, duration of treatment and acid inhibition.	12811309
Pancreatic Insufficiency, Pancreatitis, Pancreatitis, Chronic	Altered Intercellular Communication	This finding gives rise to the speculation that, apart from pancreatic inflammation, cross-linking of IgE with alimentary or other antigens might be involved in the pathophysiology of a sub-population of patients with chronic pancreatitis and manifest pancreatic insufficiency.	12811311
Inflammation, Discitis, Pathology	Altered Intercellular Communication	The associated pathologies were spondylodiscitis, narrowing in the intervertebral space, inflammation or abscess formation in the paravertebral soft tissue, and osteophyte formation.	12811509
Inflammation, Angulation deformity	Altered Intercellular Communication	None of the patients had a collapsed vertebral body, angulation deformity, or inflammation in the epidural space.	12811509
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Abnormalities in neural transmission of serotonin (5-HT) may play a role in both cognitive and neuropsychiatric features of Alzheimer disease (AD).	12811638
Inflammation, Neoplasms, Disease susceptibility, Necrosis, Epithelial metaplasia	Altered Intercellular Communication	A retrospective review of the tumors, which were over-called on FNA, showed a predominance of necrotic or cellular debris (n = 6 tumors; 22%), significant epithelial metaplasia with atypia (n = 4 tumors; 15%), background inflammation suspicious for tumor diathesis (n = 3 tumors; 11%), spindle cells (n = 1 tumor; 4%), and abundant mucin with keratinized squamous cells (n = 1 tumor; 4%).	12811857
Coughing, Upper Respiratory Infections	Altered Intercellular Communication	The one-year-old girl had recurrent respiratory inflammations and permanent cough since she was two months old.	12812019
Inflammation, Nasal Polyps, Edema	Altered Intercellular Communication	Nasal polyposis is an invalidating disease which develops through chronic inflammation which leads to tissue oedema and eventually polyps.	12812132
Communicable Diseases, Helicobacter pylori, Inflammation	Altered Intercellular Communication	There was no correlation between CD3 expression and inflammation or Helicobacter pylori (H. pylori) infection.	12812314
Inflammation	Altered Intercellular Communication	Gram negative bacteria were associated with severe anterior chamber inflammation (p=0.004), as well as greater surface of infiltrates (p=0.01).	12812878
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterised by limited bronchial reversibility and chronic neutrophilic inflammation.	12814141
ARCN1 gene, Inflammation	Altered Intercellular Communication	However, in some cases of COPD, eosinophilic inflammation is present.	12814141
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation in asthma with incomplete reversibility of airflow obstruction.	12814164
Airway structure, Asthma	Altered Intercellular Communication	In conclusion, persistent airway inflammation and increased decline in pulmonary function can be observed in both asthmatic patients with IRAO/CRAO and are of similar magnitude.	12814164
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Inflammation and immune activation appear to be important in the pathogenesis of coronary heart disease (CHD).	12814390
Inflammation, Shigella Infections	Altered Intercellular Communication	Shigella infection is characterized by the induction of acute inflammation, which is responsible for the massive tissue destruction of the intestinal mucosa.	12814438
Inflammation, Intestines, Shigella Infections	Altered Intercellular Communication	Histologically, 4-day-old mice infected with the invasive strain presented intestinal lesions and inflammation similar to those described in patients with shigellosis.	12814438
Inflammation	Altered Intercellular Communication	Moreover, cytokine and chemokine responses consistent with inflammation were observed.	12814438
Inflammation	Altered Intercellular Communication	Laboratory tests showed severe inflammation, promoting investigations for other conditions.	12814766
Inflammation, Decalcification, Edema, Spondylarthritis	Altered Intercellular Communication	In older patients, edema of the foot with severe demineralization and the laboratory evidence of inflammation should suggest a spondyloarthropathy.	12814766
Neurodegenerative Disorders, "Alzheimers Disease	Altered Intercellular Communication	Since chorionic gonadotropin increases secretion of a variety of cytokines by monocytes, and induces their inflammatory reaction and phagocytic activity, high LH levels in aging individuals may also activate microglia (mononuclear phagocyte system in the central nervous system) and contribute to the development of Alzheimer's disease and other inflammation-mediated neurodegenerative diseases.	12816543
Inflammation	Altered Intercellular Communication	(2) The severity and activity of inflammation in both the antrum and body were markedly reduced after Hp eradication (P = 0.000).	12816696
Inflammation, Blood Coagulation Disorders	Altered Intercellular Communication	Laboratory parameters monitoring inflammation and coagulopathy improved during the treatment.	12818248
Inflammation	Altered Intercellular Communication	Whenever a cervical inlet patch was observed, mucosal biopsy samples were taken to confirm the endoscopic diagnosis and to search for H. pylori and active inflammation.	12818267
Communicable Diseases, Inflammation	Altered Intercellular Communication	Active inflammation correlated with active infection in the inlet patch and the presence of antral type mucosa.	12818267
Gastrointestinal inflammation	Altered Intercellular Communication	Fecal lactoferrin is a sensitive and specific marker in identifying intestinal inflammation.	12818275
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Fecal lactoferrin was 90% specific for identifying inflammation in patients with active IBD.	12818275
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Fecal lactoferrin is sensitive and specific for detecting inflammation in chronic IBD.	12818275
Inflammation, Diarrhea, Abdominal Pain	Altered Intercellular Communication	This noninvasive test may prove useful in screening for inflammation in patients presenting with abdominal pain and diarrhea.	12818275
Subluxation of atlantoaxial joint, Inflammation, "Grisels syndrome	Altered Intercellular Communication	The concurrence of non-traumatic atlanto-axial subluxation with inflammation of the adjacent neck tissues is known as Grisel's syndrome.	12818913
Inflammation	Altered Intercellular Communication	These data indicate that T cells from poor responders are in an enhanced activation state possibly as a result of chronic inflammation.	12819237
Osteomyelitis, Chronic multifocal osteomyelitis	Altered Intercellular Communication	Chronic recurrent multifocal osteomyelitis (CRMO) is a rare, inflammatory, skeletal disease of unknown origin, which mainly affects children and adolescents in terms of cleido-spondylo-metaphysal skeletal inflammation.	12819893
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Over the years they experience a typical maturation, with the possibility of an increased thickness due to accompanying inflammation or fibrosis but actual growth of nevi is rare in adults.	12820016
Intraparenchymal Route of Administration, Inflammation	Altered Intercellular Communication	Due to massive inflammation in the porta hepatis and intraparenchymal destruction of the right bile duct, liver resection was performed 2 days later, after the patient had stabilized in the intensive care unit (ICU).	12820055
Communicable Diseases, Inflammation, Pulmonary capillary hemangiomatosis	Altered Intercellular Communication	This case supports the theory that persistent infection or inflammation may be an inciting factor in uncontrolled angiogenesis, leading ultimately to diffuse pulmonary capillary hemangiomatosis.	12821168
Inflammation, Serous, Peritonitis, Synovitis, Fever, Pleurisy	Altered Intercellular Communication	The clinical syndrome is characterised by self-limiting febrile episodes accompanied by inflammation of the serous membranes, resulting in peritonitis, pleuritis or synovitis.	12822516
Inflammation, Prostatic Intraepithelial Neoplasias, Atrophic, Carcinoma	Altered Intercellular Communication	Recently, prostatic atrophy associated with chronic inflammation has been linked to carcinoma either directly or indirectly by first developing into high-grade prostatic intraepithelial neoplasia.	12823038
Post-atrophic hyperplasia, Inflammation, Atrophic, Hyperplasia	Altered Intercellular Communication	Prostatic atrophy was classified as simple, hyperplastic (or postatrophic hyperplasia), and sclerotic and was analyzed for the presence of chronic inflammation.	12823038
Inflammation, Atrophic	Altered Intercellular Communication	Of the 100 prostates examined, 12%, 22% and 66%, respectively, had no atrophy, atrophy without inflammation (group A), and atrophy with inflammation (group B).	12823038
Inflammation, Atrophic	Altered Intercellular Communication	A striking morphologic finding was a topographical relation of focal inflammation with sclerotic atrophy in areas with erosion of the epithelium.	12823038
Inflammation	Altered Intercellular Communication	after the steroid washout), the use of fluticasone/salmeterol combination conferred significant improvements (P < 0.05) in all surrogate markers of inflammation apart from serum ECP.	12823118
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation contributes to degeneration in Alzheimer's disease (AD), not simply as a secondary phenomenon, but primarily as a significant source of pathology.	12824711
Inflammation, Data types - Address	Altered Intercellular Communication	[(123)I]iodo-PK11195 is a cellular disease activity marker and allows in vivo assessment of microglial inflammation in AD.	12824711
Intraocular inflammation, Retinal Artery Occlusion, Retinal Hemorrhage	Altered Intercellular Communication	Complications included increased intraocular pressure in six eyes (18%), intraocular inflammation and synechia formation in one eye (3%), a central retinal artery occlusion after heavy oil removal in one eye, and scattered retinal hemorrhages during follow-up in two eyes (6%).	12824833
Inflammation, Vitreous abscess	Altered Intercellular Communication	In most cases, the inflammation progressed within days and resulted in decreased vision worse than hand motions and a total vitreous abscess, despite systemic and intravitreal antibiotic injections.	12824838
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Elevated serum concentrations of YKL-40 are found in patients with diseases characterized by inflammation or ongoing fibrosis.	12825867
Inflammation, Dysplasia, Fibrosis Assessment, Amyloidosis, Hypertrophy	Altered Intercellular Communication	Microscopic evaluation showed myocyte hypertrophy (97%), vacuolization (35%), left bundle branch tissue (26%) (33% in Group 1 vs. 8% in Group 2; P=.02) and disarray (19%); interstitial fibrosis (92%), inflammation (10%) and amyloidosis (7%, all prealbumin type, all Group 1, >80 years old); arterial thickening (18%) and dysplasia (12%), and dilated venules (6%); and endocardial fibrosis (74%) (64% in Group 1 vs. 100% in Group 2; P=.0001) and chronic inflammation (17%).	12826290
Granulomatous inflammation, Peripheral T-Cell Lymphoma, Hodgkin Disease, Lymphoma, Follicular	Altered Intercellular Communication	The main differential diagnoses include granulomatous inflammation, Hodgkin's lymphoma, follicular lymphoma, and peripheral T-cell lymphomas.	12826882
Gastroesophageal reflux disease, Cardia of stomach, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Inflammation of the gastric cardia, which is the most proximal portion of the stomach, in most instances is the result of either gastroesophageal reflux disease or H. pylori infection.	12826888
Inflammation, Pancreatic aplasia, Carditis, Cardia of stomach, Goblet Cells	Altered Intercellular Communication	Routinely processed hematoxylin and eosin-stained mucosal biopsies of the gastric cardia from 30 patients with reflux-associated carditis, 25 with H. pylori-associated carditis, and 30 control patients (no reflux, no H. pylori) were evaluated for a wide variety of histologic features such as goblet cell metaplasia, presence of multilayered epithelium, type of glandular epithelium (mucous, oxyntic, mixed mucous/oxyntic), pancreatic metaplasia, overall degree of inflammation, and the quantity of individual types of inflammatory cells.	12826888
Acid reflux	Altered Intercellular Communication	In the reflux carditis group, multilayered epithelium was significantly associated with neutrophilic inflammation (p <0.05), but not any other features of chronic carditis or with any of the specific epithelial cell types.	12826888
Inflammation	Altered Intercellular Communication	The control group showed less inflammatory activity in comparison with the H. pylori group and a lower prevalence of multilayered epithelium and eosinophilic inflammation in comparison with the reflux group.	12826888
Inflammation, Acid reflux	Altered Intercellular Communication	The clinical and pathologic features of reflux carditis are distinct from H. pylori carditis and are characterized by less overall inflammation and fewer neutrophils and plasma cells.	12826888
Autoimmune Pancreatitis	Altered Intercellular Communication	Autoimmune pancreatitis is characterized by severe lymphocytic inflammation, suggesting that gallium-67 scintigraphy provides a useful tool for detecting characteristic lesions of this disease, because gallium-67 concentrates in lymphoid cells.	12826901
Keratitis	Altered Intercellular Communication	Corneal inflammation and degradation after KPro placement correlate well with the preoperative diagnostic category.	12827047
Multiple Organ Failure, Communicable Diseases, Inflammation, Shock, Cardiogenic	Altered Intercellular Communication	Patients in cardiogenic shock (CS) often present with signs of systemic inflammation that mimic infection, especially in the setting of multiple organ failure (MOF).	12827235
Neutrophilic Eccrine Hidradenitis, Urticaria, neutrophilic, Pyoderma Gangrenosum, Lymphoproliferative Disorders, Lobular panniculitis, Dermatitis, Granulomatous Angiitis	Altered Intercellular Communication	Lesions were also classified histopathologically by the dominant reaction pattern: vasculopathies of neutrophilic, lymphocytic, and granulomatous vasculitis and pauci-inflammatory subtypes (15 patients); palisading granulomatous inflammation (3 patients); sterile neutrophilic folliculitis (5 patients); dermatitis herpetiformis (1 patient); lobular panniculitis composed of neutrophilic lobular panniculitis in 2 patients and benign cutaneous polyarteritis nodosa in 1 patient; neutrophilic dermatoses, including neutrophilic urticaria, neutrophilic eccrine hidradenitis, and pyoderma gangrenosum (3 patients); interface dermatitis (3 patients); and low-grade lymphoproliferative disease of B-cell lineage representing marginal zone lymphoma in 1 patient and a clonal plasmacellular infiltrate in another patient.	12827611
Observation Method - Coagulation, Aortic Aneurysm	Altered Intercellular Communication	Patients with aortic aneurysm (AA) were in the chronic inflammatory condition and are often combined with disseminated intervascular coagulation.	12829084
Thrombophilia	Altered Intercellular Communication	AA patients were in the hypercoagulation and inflammatory condition.	12829084
Inflammation, Lung diseases	Altered Intercellular Communication	Obstructive and restrictive lung disease and markers of inflammation: data from the Third National Health and Nutrition Examination.	12829203
Septic Shock, Cystitis	Altered Intercellular Communication	Corynebacterium D2 is known to cause chronic inflammation of the bladder and proximal urinary tract but can also cause severe septic shock in immunocompetent patients.	12830376
Intraocular inflammation, Sarcoidosis	Altered Intercellular Communication	Compared to previous studies with heterogeneous ethnic composition, intraocular inflammations with confirmed sarcoidosis in German patients show more than 60 % involvement of the posterior segment.	12830396
Diabetic Nephropathy, Inflammation, Malnutrition, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	Inflammation may be involved in the pathophysiological state of malnutrition and CVD in the earlier stages of predominantly nondiabetic kidney disease.	12830455
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Kidney Diseases	Altered Intercellular Communication	Data about the relationship of inflammation to nephropathy in type 2 diabetes mellitus are scarce.	12830456
Diabetic Nephropathy, Inflammation	Altered Intercellular Communication	In addition to traditional metabolic and hemodynamic factors, it is possible to hypothesize on the participation of inflammation in the pathogenesis of diabetic nephropathy.	12830456
Inflammation, Depressed mood, Obesity, Atherosclerosis	Altered Intercellular Communication	These findings suggest a possible synergistic effect of obesity and depressive mood on chronic low level inflammation which may play a crucial role in the pathogenesis of atherosclerosis.	12831829
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Inflammation in chronic obstructive pulmonary disease (COPD) is characterised by increased neutrophilic infiltration of the airways.	12832668
ARCN1 gene, Inflammation	Altered Intercellular Communication	This drug may play a role in the resolution of neutrophilic inflammation associated with COPD and cigarette smoke.	12832668
Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	Cardiopulmonary bypass activates adhesion molecules, which are associated with systemic inflammation and organ dysfunction.	12833202
Malignant Neoplasms, Pelvic Inflammatory Disease	Altered Intercellular Communication	In this study, we discussed the recovery of 29-year-old woman with pericystitis plastica who was misdiagnosed as pelvic malignancy or a chronic/subacut pelvic inflammation at the first evaluation.	12833598
Pounds, neuron death, Functional disorder	Altered Intercellular Communication	Our findings suggest that LB-related pathology initially involves the neuronal perikarya, dendrites, and axons, causes impairment of axonal transport and synaptic transmission, and later leads to the formation of LBs, a hallmark of functional disturbance long before neuronal cell death.	12834109
Inflammation, Cartilage damage	Altered Intercellular Communication	Resorption of intraarticular blood induces an inflammation of the synovium and cartilage damage, finally leading to severe changes of the joint with complete destruction.	12836461
Degenerative polyarthritis, Refractory anemias	Altered Intercellular Communication	Thus, UC-II may serve as a novel therapeutic tool in joint inflammatory conditions and symptoms of OA and RA.	12837047
Inflammation	Altered Intercellular Communication	In the 2 patients with positive MUC7, the histologic examination showed chronic inflammation.	12837463
Vascular Diseases, Lung diseases, Pneumonitis	Altered Intercellular Communication	A pilot trial of quantitative Tc-99m HMPAO and Ga-67 citrate lung scans to detect pulmonary vascular endothelial damage and lung inflammation in patients of collagen vascular diseases with active diffuse infiltrative lung disease.	12838367
Pneumonitis	Altered Intercellular Communication	No good correlation between the degree of pulmonary vascular endothelial damage and the severity of lung inflammation was found.	12838367
Pneumonitis	Altered Intercellular Communication	In conclusion, L/L ratios on Tc-99m HMPAO and GUI on Ga-67 lung scans differ from chest X-ray findings and have the potential to detect the degree of pulmonary vascular endothelial damage and severity of lung inflammation in active IDL.	12838367
Excessive tearing, Inflammation, Conjunctivitis	Altered Intercellular Communication	Symptoms included chronic epiphora in 65 patients (52%), acute lacrimal sac inflammation in 33 (26.4%), mucocele in 6 (4.8%) and recurrent conjunctivitis in 4 (3.2%).	12838463
Blepharitis, Pain Distress Question, Epistaxis	Altered Intercellular Communication	Surgical complications included pain in 5.83%, eyelid inflammation in 5%, nasal bleeding in 0.83% and false duct in 0.83%.	12838463
Inflammation, Experimental Organism Basal Cell Carcinoma, Irritation, Traumatic injury	Altered Intercellular Communication	Although UV radiation is the major cause of basal cell carcinoma (BCC), local factors, such as chronic trauma, irritation, or inflammation, may also have some role in its etiopathogenesis.	12839614
Inflammation, Carcinogenesis	Altered Intercellular Communication	Demodicidosis may be one of the triggering factors of carcinogenesis in eyelid BCCs in otherwise predisposed people due to its traumatic/irritating effect or chronic inflammation.	12839614
Colorectal Carcinoma	Altered Intercellular Communication	This is the first report that IL6, IL8, and PPARG genes are important in relation to inflammation-related risk of sporadic CRC.	12839942
Colorectal Carcinoma	Altered Intercellular Communication	Animal models and epidemiological observations suggest that a continuous inflammatory condition predisposes to colorectal cancer (CRC), but the roles of different elements participating in inflammatory responses have been little investigated in relation to CRC.	12839942
Acute inflammation, Hepatitis	Altered Intercellular Communication	Liver biopsy revealed chronic hepatitis with moderately active portal inflammation.	12840684
Airway structure, ARCN1 gene	Altered Intercellular Communication	We are led to conclude that IL-4 might play a role in the pathogenesis of the airway inflammation and air flow limitation in COPD patients and the mechanisms of theophylline's therapeutic effects of attenuating air-flow limitation may partially depend on its anti-inflammatory effects on the airways which, in turn, is dependent on its inhibitory effects on some inflammatory mediators such as IL-4.	12840867
Inflammation, Endotoxemia	Altered Intercellular Communication	Inflammation has been reported to play an important role in cardiac surgery under cardiopulmonary bypass due to systemic endotoxemia.	12841627
allergic inflammation	Altered Intercellular Communication	Azelastine is a selective H(1)-receptor antagonist that inhibits histamine release and interferes with activation of several other mediators of allergic inflammation.	12841925
allergic inflammation	Altered Intercellular Communication	Rapid relief is consistent with H(1)-receptor antagonist action, while continued improvement up to 6 weeks may be consistent with mechanisms involving other mediators of allergic inflammation.	12841925
Granulomatous inflammation, Vasculitis, CTCAE, Necrosis	Altered Intercellular Communication	A biopsy specimen of the left orbit demonstrated necrosis, granulomatous inflammation, and vasculitis.	12842210
Granulomatous inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	A diagnosis was made of a limited form of WG, whilethe biopsy specimen of the left upper lid demonstrated granulomatous inflammation without vasculitis.	12842210
Acute inflammation, Polycystic Ovary Syndrome	Altered Intercellular Communication	Eyes with smaller clear corneal incisions and foldable IOLs had less postoperative inflammation and PCO.	12842676
Acute and chronic inflammation	Altered Intercellular Communication	Ultrasound biomicroscopy of pseudophakic eyes with chronic postoperative inflammation.	12842688
Acute and chronic inflammation	Altered Intercellular Communication	Fifty-four eyes of 51 patients with chronic noninfectious postoperative inflammation were prospectively evaluated between January 1998 and September 2001.	12842688
Pseudophakia, Acute and chronic inflammation	Altered Intercellular Communication	Irritation of ocular tissues by an IOL was the main cause of chronic postoperative noninfectious inflammation in pseudophakic eyes.	12842688
Inflammatory abnormality of the eye	Altered Intercellular Communication	After topical and systemic administration of antifungal treatment, ocular inflammation disappeared and visual acuity improved.	12843093
Sepsis, Inflammation, Brain Injuries	Altered Intercellular Communication	Liver D1 and serum T(3)/rT(3) were highest in patients who died from severe brain damage, intermediate in those who died from sepsis or excessive inflammation, and lowest in patients who died from cardiovascular collapse (P < 0.01).	12843166
Inflammation, Keratoconjunctivitis Sicca	Altered Intercellular Communication	Immune-based inflammation has been observed as a common mechanism of keratoconjunctivitis sicca (KCS).	12843889
Conjunctivitis, Keratoconjunctivitis Sicca	Altered Intercellular Communication	This study confirms that cyclosporin A may be effective in reducing conjunctival inflammation in moderate-to-severe KCS and is consistent with clinical results in this indication.	12843889
Inflammation	Altered Intercellular Communication	The inflammation appeared as a reddish area of the inner part of the eyelid, without sharp limits, but with loss of lashes.	12843904
Sebaceous Adenocarcinoma, Inflammation, Blepharitis, Eyelid Neoplasms	Altered Intercellular Communication	As some true eyelid tumors may mimic an inflammation during growth and, for example, sebaceous carcinoma may clinically present as chronic unilateral blepharitis, a surgical excisional biopsy was performed on this left eyelid.	12843904
Granulomatous inflammation	Altered Intercellular Communication	Its histopathological study showed a granulomatous inflammation, which was typical of a simple chalazion.	12843904
Inflammation	Altered Intercellular Communication	This case clearly illustrates that the chalazion may not always appear as a limited nodular inflammation of the eyelid, but may have a more diffuse clinical presentation.	12843904
Communicable Diseases, Inflammation	Altered Intercellular Communication	As the research progresses, scientists hope to bolster elderly people's response to infectious diseases and quiet the inflammation that can make aging a painful experience.	12844525
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	However, mild to moderate inflammation and fibrosis were seen in 9 patients and in 8, respectively.	12845950
Inflammation, Neoplasms, Biliary Tract Cancer, Cholangiocarcinoma	Altered Intercellular Communication	In addition to the presence of biliary cancer, biliary fibronectin was also increased in response to biliary inflammation, which limits its use as a tumor marker of cholangiocarcinoma.	12845951
palladium, Inflammation, Squamous metaplasia	Altered Intercellular Communication	To eradicate PD in long-term inflammation in the urinary bladder and development of squamous cell metaplasia of the urothelium, TUR of the affected area and intramural nerves with partial denervation of the urinary bladder is indicated.	12846090
Inflammation	Altered Intercellular Communication	Clinical picture (localised tender mass without skin signs of inflammation in an afebrile patient) and laboratory data (erythrocyte sedimentation rate 113 mm in 1 hr, fibrinogen 635 mg/dl) suggested the diagnosis of diabetic muscle infarction.	12846454
Inflammation, Cardiovascular system	Altered Intercellular Communication	The results strengthen the hypothesis that chronic inflammation is a mechanism of cardiovascular damage in dialysis patients and the role played by the IL-6 system in this mechanism.	12846758
Inflammation	Altered Intercellular Communication	Keratinocytes undergoing apoptosis in acute eczematous lesions release chemokines that attract more T cells toward the epidermis, which may further augment the inflammation and keratinocyte apoptosis.	12847282
Sepsis, Inflammation	Altered Intercellular Communication	Elevated nucleosome levels in systemic inflammation and sepsis.	12847387
Carotid Atherosclerosis, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Association between carotid atherosclerosis and markers of inflammation in rheumatoid arthritis patients and healthy subjects.	12847676
Refractory anemias, Inflammation, Rheumatoid Arthritis, Carotid Atherosclerosis	Altered Intercellular Communication	To examine the relationship between markers of systemic inflammation and carotid atherosclerosis in patients with rheumatoid arthritis (RA) and healthy controls.	12847676
Inflammation, Dental Plaque	Altered Intercellular Communication	Carotid plaque displayed a similar relationship to markers of inflammation.	12847676
Refractory anemias, Inflammation, Dental Plaque	Altered Intercellular Communication	Increased carotid artery IMT and the presence of carotid plaque are associated with markers of systemic inflammation in patients with RA and in healthy subjects.	12847676
Refractory anemias, Inflammation, Atherosclerosis, Chronic inflammatory disorder	Altered Intercellular Communication	This observation is consistent with hypotheses that assign a role to systemic inflammation in atherosclerosis, and may have implications regarding RA and other chronic inflammatory diseases.	12847676
Pain Distress Question, Inflammation	Altered Intercellular Communication	Nimesil relieved pain and inflammation (ESR and seromucoid level lowered significantly).	12847901
Inflammation, Heart failure	Altered Intercellular Communication	Cutaneous vascular reactivity is reduced in aging and in heart failure: association with inflammation.	12848618
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The results were correlated with plasma concentrations of vascular risk factors and markers for endothelial dysfunction and inflammation.	12848618
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a role in the pathogenesis of atherosclerosis.	12848806
Inflammation, Acute Coronary Syndrome, Coronary Artery Disease	Altered Intercellular Communication	Attempts are made to use markers of inflammation as prognostic factors in coronary artery disease and acute coronary syndromes.	12848806
Inflammation, Ischemia	Altered Intercellular Communication	The correlation between inflammation and silent postinfarction ischemia is unknown.	12848806
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	While chronic inflammation, extracellular matrix destruction and increased airway epithelial cell apoptosis are reported in chronic obstructive pulmonary disease, the understanding of the basic pathogenesis of the disease is limited and there are no effective treatments.	12848850
Communicable Diseases, Inflammation, Coronary Artery Disease	Altered Intercellular Communication	[Study on the correlation of between infection, inflammation and coronary artery disease].	12848920
Communicable Diseases, Cytomegalovirus, Coronary Artery Disease, Inflammation	Altered Intercellular Communication	The aim of this study was to study relationship between infection of Cp, Hp and CMV, systemic inflammation and coronary artery disease (CAD).	12848920
Communicable Diseases, Inflammation	Altered Intercellular Communication	C-reactive protein was an independent parameter of CAD, but the increased systemic inflammation in CAD did not seem to be related to aforesaid infection.	12848920
Inflammation, Kidney Failure	Altered Intercellular Communication	Renal insufficiency, CRP, and angiographic CAD, although correlated, are largely independent predictors of cardiovascular risk, suggesting the importance of both inflammation and as yet undefined RI-related risk factors.	12849660
Inflammation	Altered Intercellular Communication	We investigated whether the bacterium persistent inflammation or the expression of the cytotoxin-associated gene A (CagA) may affect serum lipids as well as Lipoprotein(a).	12849867
Inflammation, Dyslipidemias, Diabetes Mellitus, Obesity, No metabolic abnormalities	Altered Intercellular Communication	On the other hand, several metabolic abnormalities such as dyslipidemia, hyperinsulinemia/insulin-resistance, diabetes, and obesity causes inflammation followed by a later rise in arterial BP.	12850386
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	We investigated the role of chronic inflammation in the modulation of BP independently of other traditional cardiovascular risk factors and atherosclerotic lesions.	12850386
Inflammation	Altered Intercellular Communication	These results suggest that chronic inflammation may play a role in the modulation of arterial BP.	12850386
Inflammation, Aortic Aneurysm, Abdominal, Aneurysm	Altered Intercellular Communication	Inflammation in the wall of abdominal aortic aneurysm and its role in the symptomatology of aneurysm.	12850808
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is associated with inflammation of airway epithelium, including an increase in the number of intraepithelial T cells.	12851215
Inflammation	Altered Intercellular Communication	Sphingolipids are emerging as important signaling molecules that may be produced by cardiac tissue during ischemic stress or as a consequence of inflammation.	12851609
Inflammation, Coronary Arteriosclerosis, Coronary Artery Disease	Altered Intercellular Communication	Because both inflammation and myocardial ischemia are associated with coronary artery disease (CAD), a study was designed to test the ability of serum sphingolipids to predict obstructive CAD.	12851609
Inflammatory abnormality of the eye	Altered Intercellular Communication	She had no previous history of ocular inflammation or ocular surgery.	12854029
Inflammatory abnormality of the eye	Altered Intercellular Communication	Her medical history was negative for systemic diseases associated with ocular inflammation.	12854029
Inflammation, Pseudoaneurysm	Altered Intercellular Communication	A pseudoaneurysm was found in the thoracoabdominal aorta, with inflammation in the aortic wall.	12854468
Inflammation	Altered Intercellular Communication	The pathological findings of his nasal mucosa and lacrimal sac showed chronic inflammation and no typical changes of WG.	12854504
ARCN1 gene, Inflammation, Bacterial Infections	Altered Intercellular Communication	In the future, the pathogenic role of bacterial infection in exacerbations of COPD should be further investigated, especially the role of bacterial infection in relation to local and systemic inflammation.	12854626
Inflammation, Stenosis	Altered Intercellular Communication	Stricture formation in the middle of the Ultraflex stent occurred bilaterally, at the level of anastomosis in one patient in whom stent placement was undertaken in the presence of inflammation.	12856743
Inflammation	Altered Intercellular Communication	Angiotensin converting enzyme (ACE) plays an important role in the physiology of vasculature, blood pressure and inflammation.	12858018
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	ACE gene polymorphism in an inflammation associated osteoarthritis (OA) patients is not known.	12858018
Foot-and-Mouth Disease, Inflammation	Altered Intercellular Communication	Thereafter, endoscopy showed initial aphthous lesions with minimal histological signs of inflammation.	12858208
Refractory anemias, Inflammation, destruction joint	Altered Intercellular Communication	Two years of HRT in women with active RA had significant ameliorating effects on inflammation, DAS28 response, and BMD and was associated with slower progression of radiological joint destruction.	12858441
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Inflammation is increasingly recognized as having an important role in patients with acute coronary syndromes.	12860213
Cessation of life, Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	An elevated WBC count at hospital admission, although only a crude index of inflammation, nevertheless is an independent predictor of death at 6 months in patients with acute coronary syndromes.	12860213
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	This finding supports a pivotal role for inflammation in acute coronary syndromes.	12860213
Inflammation	Altered Intercellular Communication	Importantly, this study suggests that in-hospital revascularization may mitigate some of the excess risk due to inflammation.	12860213
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Chemokines and their receptors are considered important contributors in cell migration and inflammation in chronic inflammatory disorders.	12860725
Intestinal metaplasia, Inflammation, Gland	Altered Intercellular Communication	After eradication, three sites in the remnant stomach showed similar histological changes: significant decreases in inflammation and activity scores (P < 0.001) and no significant changes in glandular atrophy and intestinal metaplasia scores.	12861401
Inflammation, Hydrops	Altered Intercellular Communication	The destruction of the acetabulum and the femoral head can lead to hydrops in the hip joint and, via a communication between the joint and the iliopectineal bursa, to inflammation of the bursa.	12861671
Inflammation, Allergic	Altered Intercellular Communication	In the present investigation, we compared the concentration of various nonspecific plasma proteins, mostly known as inflammation markers, in an allergic and a healthy population.	12861853
Inflammation, Arteritis	Altered Intercellular Communication	Histochemistry showed signs of strong inflammation in the arteritis samples.	12864775
Inflammation, Temporal Arteritis	Altered Intercellular Communication	However, these findings do not rule out the possibility of bacterial degradation products as stimulants of chronic inflammation, or of viable microbes as triggering factors of acute temporal arteritis.	12864775
Inflammation	Altered Intercellular Communication	In addition, there was a reduction in hepatic inflammation and improved organ blood flow, suggesting an important role for TNF-alpha in mediating the circulatory disturbances in AH.	12865279
Inflammation	Altered Intercellular Communication	NO prevents atherogenesis and inflammation in vessel walls by inhibition of cell proliferation and cytokine-induced endothelial expression of adhesion molecules and proinflammatory cytokines.	12865413
Crohn Disease, Ascariasis, Gastrointestinal inflammation, Eosinophilic inflammation	Altered Intercellular Communication	Selective alterations in mast cell subsets and eosinophil infiltration in two complementary types of intestinal inflammation: ascariasis and Crohn's disease.	12865626
Gastrointestinal inflammation	Altered Intercellular Communication	These two types of intestinal inflammation are complementary with regard to T cell response (TH1 versus TH2), prevalence and environmental factors.	12865626
Gastrointestinal inflammation	Altered Intercellular Communication	Our results indicate that T cell responses (TH1 or TH2) are associated with different MC subsets in intestinal inflammation.	12865626
Inflammation	Altered Intercellular Communication	Changes remote from the focus of inflammation point to the systemic nature of the different MC responses.	12865626
Peripheral Vascular Diseases, Inflammation, Atherosclerosis	Altered Intercellular Communication	Peripheral arterial disease (PAD) is a common manifestation of atherosclerosis that is associated with systemic inflammation.	12866607
Inflammation, Atherosclerosis	Altered Intercellular Communication	These results confirm that white blood cell activation is characteristic of systemic atherosclerosis and that these inflammation markers increase in conditions of hemodynamic stress.	12866607
Nausea, Bothered by Vomiting	Altered Intercellular Communication	Nausea and vomiting may be treated when one takes into account which centres in the brain and neurotransmitters are involved, together with the site of action of the medication.	12868155
Inflammation	Altered Intercellular Communication	Leucocytes have been shown to play a fundamental role in the pathophysiology of inflammation.	12868787
Inflammation, Mucous Membrane	Altered Intercellular Communication	Inflammation and mucosal atrophy were scored according to the Updated Sydney System.	12869086
Sepsis, Inflammation, Blood Coagulation Disorders	Altered Intercellular Communication	Sepsis is associated with systemic inflammation, coagulopathy, and disrupted protein C (PC) pathway function.	12869495
Inflammation, Blood Coagulation Disorders	Altered Intercellular Communication	VL+/- status did not appear to influence baseline biomarkers of coagulopathy and inflammation or disease severity, with the exception that vasopressor usage was less in VL+/- patients (46.2% versus 63.0%; P =.009).	12869495
Urethritis	Altered Intercellular Communication	No serious adverse events (AEs) or urethral inflammation was detected.	12869836
Klinefelter Syndrome, Lesion of liver	Altered Intercellular Communication	Although the association could be casual, the sex hormone imbalance present in Klinefelter syndrome may suggest a role in the development of this benign liver lesion.	12869895
Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Neutrophilic inflammation in induced sputum of patients with idiopathic pulmonary fibrosis.	12870724
Upper Respiratory Infections, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	This paper adresses the issue of whether the safe and non-invasive method of sputum induction is a suitable tool to study respiratory tract inflammation in IPF.	12870724
Inflammation, Lung Diseases, Interstitial, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	These data confirm the established role of neutrophilic inflammation in the pathogenesis of IPF, and show the potential of induced sputum to directly study inflammatory processes and surrogate markers in interstitial lung diseases like IPF.	12870724
Inflammation, Virus Diseases, Ear Inflammation	Altered Intercellular Communication	Otitis media with effusion may be an inflammatory condition; both bacteria and viral infections could play a part in this inflammation.	12871248
Inflammation, Virus Diseases, Ear Inflammation	Altered Intercellular Communication	Otitis media with effusion may be an inflammatory condition; both bacteria and viral infections could play a part in this inflammation.	12871248
Inflammation, Thrombosis, Atherosclerosis	Altered Intercellular Communication	Inflammation, thrombosis and atherosclerosis: results of the Glostrup study.	12871360
Inflammation, Thrombosis, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation and thrombosis are important mechanisms in cardiovascular disease, as illustrated by the consistent association between inflammatory and hemostatic variables and the risk of cardiovascular events in epidemiological studies.	12871360
Inflammation, Thrombosis, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	In conclusion, in the Glostrup population study, thrombosis and inflammation are associated with the severity of atherosclerosis, as reflected by IMT and plaque occurrence.	12871360
Inflammation, Thrombosis	Altered Intercellular Communication	Early graft failure after coronary artery bypass grafting (CABG) is related to thrombosis and inflammation in the grafted vessel(s).	12871452
Inflammation, Data types - Address, Nerve Degeneration	Altered Intercellular Communication	However, murine plaques appear to be less cross-linked and the mice show a lower degree of inflammation and neurodegeneration than AD patients.	12871569
glycation, Dental Plaque, Data types - Address	Altered Intercellular Communication	'Advanced glycation endproducts (AGEs)', formed by reaction of proteins with reactive sugars or dicarbonyl compounds, are able to cross-link proteins and to activate glial cells, and are thus contributing to plaque stability and plaque-induced inflammation in AD.	12871569
Inflammation, Abnormal thrombosis	Altered Intercellular Communication	There was no association of inflammation with endothelial activation (sEsel) or the presence of abnormal thrombogenesis (high F1+2 levels) in AF.	12871695
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	No necrosis, inflammation, and fibrosis supporting the secondary origin of this lesion was found.	12874907
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Chemotactic cells known as microglia are involved in the inflammation associated with pathology in Alzheimer's disease (AD).	12875339
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In the surrounding dermis, there was dense chronic inflammation, fibrosis, and granules of dark red pigment.	12876493
Inflammation, Small vessel vasculitis	Altered Intercellular Communication	Endotoxin possibly induced the inflammation in this apparently unique case of pleuropulmonary small vessel vasculitis.	12877735
ARCN1 gene, Airway structure, Lithuania, mucus secretion, Chronic Obstructive Airway Disease, Asthma	Altered Intercellular Communication	Cysteinyl leukotrienes (LT) are involved in airway inflammation and mucus hypersecretion, characteristically present in asthma and chronic obstructive pulmonary disease (COPD).	12877822
Carcinoma	Altered Intercellular Communication	Based on histopathology results of the 147 biopsies, most cervical lesions were invasive carcinomas and non specific inflammations (NSI).	12878093
Conjunctivitis	Altered Intercellular Communication	Refractory medial conjunctival inflammation associated with jones tubes.	12878880
Conjunctivitis	Altered Intercellular Communication	To report an uncommon complication of refractory medial conjunctival inflammation associated with Jones tubes in 2 patients. "	12878880
Conjunctivitis, Episcleritis	Altered Intercellular Communication	The medial conjunctival inflammation, which resembled episcleritis, persisted despite removal of the Jones tube in the first patient.	12878880
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histopathologic examination revealed conjunctival tissue with inflammation and fibrosis.	12878880
Conjunctivitis	Altered Intercellular Communication	There have been no previous reports indicating the persistence of medial conjunctival inflammation after Jones tube removal, as was the case in our first patient.	12878880
Inflammation	Altered Intercellular Communication	Orbital and tibial biopsies showed a nonspecific chronic inflammation.	12878885
Pustulosis of Palms and Soles, Acne, Rhabdomyosarcoma, Synovitis, Osteitis, Sapho, Ewings sarcoma, Chronic multifocal osteomyelitis, Orbital Pseudotumor, Osteomyelitis, Hyperostosis	Altered Intercellular Communication	Idiopathic inflammation that involves the orbit (orbital pseudotumor) and that has systemic manifestations may mimic more serious conditions, such as metastases from rhabdomyosarcoma or Ewing sarcoma, chronic recurrent multifocal osteomyelitis (CRMO), and SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis).	12878885
Inflammation, Rupture, Fasciitis, Fibromatosis, Cartilaginous metaplasia	Altered Intercellular Communication	Histological examination found inflammation in all cases (fasciitis or rupture), calcification of the aponeurosis in four cases, cartilaginous metaplasia in four and fibromatosis in four.	12879710
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Long-term risk of mortality in patients with myocardial infarction is thought to be linked with plasma concentrations of proinflammatory cytokines and CRP (markers of inflammation).	12879762
Inflammation, Discitis	Altered Intercellular Communication	Spondylodiscitis is a rare but prolonged inflammation of two adjacent vertebral bodies and the disk in between.	12879807
Sarcoidosis, Inflammatory abnormality of the eye	Altered Intercellular Communication	The spectrum of ocular inflammation in sarcoidosis is wide.	12880455
Pharyngitis	Altered Intercellular Communication	Clinically, 5% of these subjects had evidence of nasopharyngeal inflammation.	12880664
Pharyngitis, physiopathological	Altered Intercellular Communication	If nasopharyngeal inflammation and hypertrophied adenoids are significantly correlated to ET dysfunction and persistent OM, this sample should be free of middle-ear (ME) disease.	12880664
Uveitis	Altered Intercellular Communication	To assess efficacy and complications of trans-Tenon's retrobulbar infusion of triamcinolone acetonide for posterior uveitic inflammation.	12881336
Uveitis	Altered Intercellular Communication	Trans-Tenon's retrobulbar triamcinolone infusion may be a safe and effective treatment for posterior uveitic inflammation.	12881336
Inflammation, Pain Distress Question	Altered Intercellular Communication	The anterior chamber remained quiet in all cases but one, which was examined 30 minutes after the injection, and there was no periorbital inflammation or pain.	12881337
Fibrinous, Serous, Microthrombosis, Hemorrhagic inflammation	Altered Intercellular Communication	A mixture features of serous, fibrinous and hemorrhagic inflammation were seen in most pulmonary alveoli with engorgement of capillary and there were microthrombosis in some capillary.	12882681
Weight Gain	Altered Intercellular Communication	Inflammation-sensitive plasma proteins are associated with future weight gain.	12882928
Inflammation, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Cross-sectional studies have associated obesity and other components of the so-called metabolic syndrome with low-grade inflammation.	12882928
Weight Gain	Altered Intercellular Communication	This study explored whether elevated levels of inflammation-sensitive plasma proteins (ISPs) (fibrinogen, orosomucoid, alpha1-antitrypsin, haptoglobin, and ceruloplasmin) are associated with future weight gain.	12882928
Inflammation, Metabolic Syndrome X, Cardiovascular Diseases	Altered Intercellular Communication	This relation could contribute to the relation between inflammation, the metabolic syndrome, and cardiovascular disease.	12882928
Communicable Diseases, Pain Distress Question, Myocarditis, effusion	Altered Intercellular Communication	Clinical presentation may be the result of the infectious process itself or the pericardial inflammation causing pain, effusion, and hemodynamic effects.	12884144
Inflammation, Ulcer	Altered Intercellular Communication	The lymph nodes at the liver hilum were needle-aspirated, this showed granulomatous inflammation similar to the biopsies of the ulcers.	12884146
Inflammation, Fibrosis Assessment, Edema, Neoplasms	Altered Intercellular Communication	Physical examination and conventional imaging by CT and MRI do not always accurately differentiate between residual or recurrent tumor and posttreatment inflammation, fibrosis, edema, or scarring.	12884346
Airway structure, Asthma	Altered Intercellular Communication	ECP released from the granules of activated eosinophils is regarded to be a marker of airway inflammation in asthma.	12884561
Inflammation, Tissue injury	Altered Intercellular Communication	The inflammation charge cells such as the macrophages, neutrophils, endothelial cells, and fibroblasts are activated in surgical sites when tissue injury occurs due to the operation.	12884773
Tumor necrosis, Inflammation	Altered Intercellular Communication	Proinflammatory cytokines such as tumor necrosis factor alpha, interleukin (IL)-1, IL-6, and IL-8 are induced from the activated inflammation charge cells.	12884773
Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	In this manuscript, we explain the pathogenesis of SIRS and CARS following surgical stress by analyzing cytokine production and surface membrane molecules in the inflammation charge cells.	12884773
Bronchitis, Chronic, Bronchitis	Altered Intercellular Communication	Resolution of bronchial inflammation is related to bacterial eradication following treatment of exacerbations of chronic bronchitis.	12885984
Inflammation, Bronchitis	Altered Intercellular Communication	Recent studies of the role of bacteria in chronic bronchitis have shown that bacterial colonisation is associated with enhanced inflammation and that purulent acute exacerbations of chronic bronchitis (AECB) are associated with bacteria and characterised by increased inflammation.	12885984
Bronchitis	Altered Intercellular Communication	Changes in bronchial inflammation in response to the success or failure of bacterial eradication following AECB were therefore studied.	12885984
Bronchitis	Altered Intercellular Communication	Resolution of bronchial inflammation following AECB is related to bacterial eradication.	12885984
Inflammation, Rasmussen Syndrome	Altered Intercellular Communication	Rasmussen syndrome: multifocal spread of inflammation suggested from MRI and PET findings.	12887447
Inflammation	Altered Intercellular Communication	In contrast, [11C]methionine PET demonstrated multifocal uptake regions, which corresponded anatomically to the FLAIR lesions, suggesting sites of underlying chronic inflammation.	12887447
Inflammation, Hemorrhage, Perforation (observation), Obstruction, Malabsorption Syndrome	Altered Intercellular Communication	Approximately 1.3% of the population has JID, of whom approximately 10% present with life-threatening complications such as inflammation, perforation, bleeding, obstruction and malabsorption.	12887523
Chronicity, Inflammation, Colonization	Altered Intercellular Communication	Degree of chronicity and activity of inflammation, mucus depletion and regeneration of foveolar epithelium by regenerating epithelium and H. pylori colonization were scored in antral biopsies.	12889554
Inflammation	Altered Intercellular Communication	The histological differences between paediatric patients and adults are focused on signs of chronic inflammation and regeneration.	12889554
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver samples were taken from the patients to evaluate the degree of inflammation and fibrosis.	12890337
Fibrinous, Serous, Hemorrhagic inflammation	Altered Intercellular Communication	A combination of serous, fibrinous and hemorrhagic inflammation was seen in most of the pulmonary alveoli with the engorgement of capillaries and detection of micro-thrombosis in some of these capillaries.	12890365
Inflammation, Aggressive behavior, prostatitis	Altered Intercellular Communication	Increased prostate-specific antigen in subclinical prostatitis: the role of aggressiveness and extension of inflammation.	12890953
Inflammation, Aggressive behavior, Prostate	Altered Intercellular Communication	We retrospectively reviewed and scored the extent and aggressiveness of inflammation in prostate specimens of BPH, according to the scale that has been reported by Irani et al.	12890953
Inflammation, Aggressive behavior	Altered Intercellular Communication	Median PSA levels in grades 0, 1 and 2 of aggressiveness of inflammation were 3.2, 4.2 and 5.8 respectively.	12890953
Inflammation, prostatitis	Altered Intercellular Communication	Aggressiveness grade of the inflammation in subclinical prostatitis is the most important morphological factor that is responsible for PSA elevation.	12890953
Inflammation, Aggressive behavior	Altered Intercellular Communication	We believe that it should be a more accurate guide for the clinician if pathologists report on the aggressiveness grades of the inflammation, especially on initial prostate biopsies, in order to help for timing of the further biopsy.	12890953
Peripheral Vascular Diseases, Inflammation, Endothelial dysfunction, atherosclerotic	Altered Intercellular Communication	Endothelial dysfunction in peripheral arterial disease is related to increase in plasma markers of inflammation and severity of peripheral circulatory impairment but not to classic risk factors and atherosclerotic burden.	12891123
Inflammation, Impaired	Altered Intercellular Communication	Inflammation and severity of circulatory impairment are implicated in the pathophysiology of dysfunctional endothelium in PAD.	12891123
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver specimens were also graded according to the magnitude of inflammation and fibrosis.	12891546
Refractory anemias, Inflammation, destruction joint, Rheumatoid Arthritis	Altered Intercellular Communication	To examine whether cartilage oligomeric matrix protein (COMP) correlates with inflammation and/or joint destruction of patients with rheumatoid arthritis (RA) and to test COMP as predicting factor for the outcome of patients with established RA.	12892252
Inflammation, Prostate	Altered Intercellular Communication	The prolonged elevation of cPSA indicates a long-lasting inflammation of the nonadenomatous parts of the prostate.	12893335
Inflammation, Blood Clot	Altered Intercellular Communication	Skin biopsy specimens demonstrated microvascular occlusions with fibrin thrombi but no dermal inflammation.	12894110
Adenocarcinoma, Inflammation, Adult Anaplastic Ependymoma	Altered Intercellular Communication	Highly anaplastic extraventricular ependymoma arising in an adult, mimicking metastatic adenocarcinoma with heavy stromal inflammation and emperiporesis.	12895233
Inflammation, septic	Altered Intercellular Communication	Lipid-based parenteral nutrition in septic patients may thus exert profound influence on sequelae and status of immunocompetence and inflammation.	12897994
Inflammation	Altered Intercellular Communication	Astrocytes play key roles in CNS development, inflammation, and repair by producing a wide variety of cytokines, chemokines, and growth factors.	12898703
Gastritis	Altered Intercellular Communication	Within the group of 79 patients, gastric mucosa inflammation was observed in all patients chronically drinking alcohol and in 72% patients who were the control.	12898897
Inflammation	Altered Intercellular Communication	13 out of 14 people with this type of inflammation had been drinking alcohol for at least 10 years.	12898897
Sclerosing inflammation	Altered Intercellular Communication	The studies did not show any relation existing between the percentage of cases with atrophic inflammation and the kind of drinks or the content of ethanol in them.	12898897
Inflammation	Altered Intercellular Communication	The results prove that continuous abuse of alcohol predisposes to atrophic inflammation of the gastric mucosa, and the appearance of this type of inflammatory changes is related to the duration of addiction.	12898897
Inflammation	Altered Intercellular Communication	Angiotensin-converting enzyme (ACE) plays a key role in the metabolism of angiotensin II (AT II) and inactivation of bradykinins and tachykinins, which are potent bronchialconstrictors and mediators of inflammation asthma, and ACE is heavily expressed in the lungs.	12899394
Airway structure, Bronchitis	Altered Intercellular Communication	[Clinical feature and airway inflammation in eosinophilic bronchitis].	12899771
Airway structure, Coughing	Altered Intercellular Communication	EB, an eosinophilic airway inflammation, is one of important causes of chronic cough and responds well to corticosteroid therapy.	12899771
Inflammation, Blood Clot	Altered Intercellular Communication	Pathological examination was made to the lung, liver, and kidney to observe the amount of small thrombus and inflammation.	12899796
Inflammation, Reperfusion Injury, Aortic Aneurysm, Thoracoabdominal	Altered Intercellular Communication	Patients undergoing thoracoabdominal aortic aneurysm (TAAA) repair suffer extensive ischemia-reperfusion and considerable systemic inflammation.	12900342
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	These results support the hypothesis that systemic inflammation is an independent risk factor for CKD.	12900806
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	Linkage of hypoalbuminemia, inflammation, and oxidative stress in patients receiving maintenance hemodialysis therapy.	12900810
Inflammation, Cardiovascular morbidity	Altered Intercellular Communication	Increased biomarkers of acute-phase inflammation and oxidative stress are highly prevalent and also correlate with cardiovascular morbidity and mortality.	12900810
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	The extent to which hypoalbuminemia, biomarkers of inflammation, and biomarkers of oxidative stress are linked in this patient population is unknown.	12900810
Inflammation	Altered Intercellular Communication	We hypothesized that a high proportion of hypoalbuminemic hemodialysis patients also would manifest increased levels of biomarkers of inflammation and oxidative stress.	12900810
Inflammation	Altered Intercellular Communication	There is a high prevalence of inflammation and oxidative stress in the maintenance hemodialysis population.	12900810
Inflammation, Cardiovascular morbidity, Hypoalbuminemia	Altered Intercellular Communication	Hypoalbuminemia, acute-phase inflammation, and oxidative stress may act synergistically to increase cardiovascular morbidity and mortality risk in maintenance hemodialysis patients.	12900810
Malnutrition, Inflammation, Muscular Atrophy	Altered Intercellular Communication	Although inflammatory indices have been associated with malnutrition in these patients, the role of inflammation in muscle wasting has not yet been determined.	12900811
Inflammation, Atherosclerosis	Altered Intercellular Communication	Advancement in understanding the pathogenesis of atherosclerotic vascular disease suggests a central role of inflammation in atherogenesis.	12900819
palladium, Inflammation	Altered Intercellular Communication	However, clinical data evaluating the role of inflammation in atherogenesis are sparse in peritoneal dialysis (PD) patients.	12900819
Inflammatory abnormality of the eye, Traumatic injury, Corneal Diseases	Altered Intercellular Communication	Exclusion criteria included history of corneal disease, ocular inflammation, trauma, contact lens wearing and surgery.	12903450
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	To quantify the relationship between inflammation and angiogenesis in synovial tissue from patients with osteoarthritis (OA).	12905470
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Hematoxylin and eosin staining and histologic grading for inflammation were performed for 104 patients who met the American College of Rheumatology criteria for OA and had undergone total joint replacement or arthroscopy.	12905470
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Synovial tissue samples from 32 (31%) of 104 patients with OA showed severe inflammation; thickened intimal lining and associated lymphoid aggregates were often observed.	12905470
Inflammation	Altered Intercellular Communication	The EC fractional area, EC proliferation, and VEGF immunoreactivity all increased with increasing histologic inflammation grade and increasing macrophage fractional area.	12905470
Inflammation	Altered Intercellular Communication	No inflammation or angiogenic indices were significantly correlated with radiographic scores.	12905470
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Inflammation and angiogenesis in the synovium are associated with OA.	12905470
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The angiogenic growth factor VEGF generated by the inflamed synovium may promote angiogenesis, thereby contributing to inflammation in OA.	12905470
Pneumonitis	Altered Intercellular Communication	Group 1 consisted of 11 patients (8 with and 3 without lung inflammation).	12905481
Pneumonitis	Altered Intercellular Communication	Group 2 consisted of 15 subjects (7 healthy controls and 2 patients with and 6 without lung inflammation).	12905481
Low Vision, Inflammation, Traumatic injury, Anterior subcapsular cataract	Altered Intercellular Communication	Anterior subcapsular cataracts cause a serious loss of vision and are normally associated with ocular trauma, inflammation or clinical skin conditions.	12907166
Inflammatory Bowel Diseases, Pyoderma Gangrenosum, Ulcer	Altered Intercellular Communication	Pyoderma gangrenosum is an immune-mediated inflammatory condition characterized by ulcerative skin lesions affecting 1-2% of patients with inflammatory bowel disease (IBD).	12907338
Data types - Address	Altered Intercellular Communication	This difference was even larger between healthy volunteers and patients developing inflammation-related AD (P = 0.00033).	12907604
Pneumonitis	Altered Intercellular Communication	Decreased activity of base excision repair pathway for epsilonA and epsilonC is associated particularly with inflammation-related lung AD.	12907604
Inflammation, Thrombosis, Dental Plaque	Altered Intercellular Communication	No local thrombosis, plaque compression, or inflammation was observed.	12907816
Inflammation, Specimen Source Codes - Abscess	Altered Intercellular Communication	In patients with severe complications such as abscess or fulminant inflammation, non-invasive diagnostic examination, abdominal CT scan for example, is recommended.	12908570
Granuloma, Inflammation, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Tuberculosis granulomas were noted in 32/63 cases, tuberculoid granulomas in 18/63, pyoepitheloid granuloms in 10/63, and non-specific inflammation in 3/63.	12909824
Inflammation, Granuloma	Altered Intercellular Communication	A second biopsy highlighted an inflammation with numerous tuberculoid granulomas.	12909832
Necrotizing granulomatous inflammation	Altered Intercellular Communication	The differential diagnosis includes other granulomatous ocular inflammations.	12910202
Squamous cell carcinoma, Cervical Adenocarcinoma	Altered Intercellular Communication	Hormonal factors may play a more prominent role in cervical adenocarcinoma than squamous cell carcinoma.	12910527
Inflammation, Erythema, Psoriasis	Altered Intercellular Communication	Benefit effects of thermal water and muds, which are important parameters in psoriasis' treatment, they are excellent to reduce inflammation, scaling, and erythema.	12910806
Inflammation	Altered Intercellular Communication	Arterial vases with signs of endothelioangiitis and aspecific inflammation.	12910811
Inflammation, Specimen Source Codes - Abscess	Altered Intercellular Communication	After emergent laminectomy and evacuation of abscess, inflammation was gradually improved.	12911000
Inflammation	Altered Intercellular Communication	Serum alpha1-antitrypsin but not complement C3 and C4 predicts chronic inflammation in hemodialysis patients.	12911163
HD Term Type, Inflammation	Altered Intercellular Communication	We studied whether predialysis serum levels of positive acute phase markers such as alpha1-antitrypsin (AT), and complement components C3 and C4 could identify the presence of chronic inflammation in maintenance hemodialysis (HD) patients.	12911163
HD Term Type, Inflammation	Altered Intercellular Communication	Serum AT levels above 1.74 g/L and below 1.38 g/L may select the HD patients with severe inflammation from those without.	12911163
Adenocarcinoma, Inflammation, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	Among the results of cytologic examinations, seven had inflammation, two had atypical squamous cells of undetermined significance (ASC-US), ten had high-grade cervical intraepithelial neoplasia (CIN), and one had adenocarcinoma.	12911731
allergic inflammation	Altered Intercellular Communication	In addition, the level of L-selectin was reduced on neutrophils derived from the blood during allergic inflammation.	12911790
Inflammation	Altered Intercellular Communication	The predominant pathological findings in the early phase were uniform periurethral hemorrhagic necrosis, extensive urothelial denudation and varying degrees of inflammation.	12913720
Inflammation	Altered Intercellular Communication	Synovial macrophages, fibroblast-like cells, and lymphocytes expressed BLT2 mRNA in RA synovial tissues showing active inflammation.	12913925
Inflammation, Arthritis	Altered Intercellular Communication	The results were related to radiological signs of destructive arthritis, duration of the disease, and laboratory markers of inflammation.	12913926
Cholecystitis, Fibrosis Assessment, Inflammation, Chronic cholecystitis	Altered Intercellular Communication	Xanthogranulomatous cholecystitis is a rare variant of chronic cholecystitis characterized by severe proliferative fibrosis and accumulation of lipid-laden macrophages in areas of destructive inflammation.	12914366
Communicable Diseases, Inflammation	Altered Intercellular Communication	Inflammation or infection was excluded by serological examination.	12915989
Syphilis, Tuberculosis, Sialometaplasia, Necrotizing	Altered Intercellular Communication	Beside specific inflammations (lues, tuberculosis) necrotizing sialometaplasia belongs to these uncommon medical conditions.	12915989
Inflammation, Nasal Polyps	Altered Intercellular Communication	There is a negative relevance tendency of NO and TNF-alpha in nasal polyp tissue which reveals the possible negative feedback of NO in the inflammation.	12916351
Inflammation, Nasal Polyps	Altered Intercellular Communication	The study confirms the theory of microenvironment of nasal polyp and reveals that nasal polyp is separated relatively from and associated closely with the inflammation of nasal cavity.	12916351
Chronic inflammation, Cyst, Mycoses, Malignant Neoplasms, Acute inflammation	Altered Intercellular Communication	Fifteen cases with sphenoid sinusitis(including 2 cases with acute inflammation, 3 cases with chronic inflammation, 8 cases with cyst, 2 cases with mycosis), 3 cases with malignant tumor.	12916354
Inflammation, Overweight	Altered Intercellular Communication	Our results suggest a state of low-grade systemic inflammation not only in overweight and obese persons, but also in normal-weight persons with large weight fluctuation, possibly explaining in part the positive association between weight fluctuation and CVD.	12917711
Inflammation, Malnutrition	Altered Intercellular Communication	Our results suggest that the age-related decline in plasma levels of IGF I, IGF II and IGFBP3 occurs independently from malnutrition and inflammation processes.	12917753
nervous system disorder, Inflammation, Abscess, Tuberculosis	Altered Intercellular Communication	The patients with a predominantly exudative-necrotic component of inflammation exhibited a severe clinical course with frequent neurological disorders, large abscesses in the paravertebral tissues, inflammatory changes in the leukogram, enhanced specific T-lymphocytic activity in the PPD blast-transformation reaction, significant increases in the levels of tuberculosis antibodies and IgE, IL-2 and it soluble IL-2 receptor RR-alpha, an excessively high increase in the functional activity of neutrophilic granulocytes, and lower with IgG2.	12918237
Inflammation, Granular cell tumor, Undifferentiated carcinoma, Granulomatous inflammation, Sarcoidosis, Plasmacytoma, Lymphoma, Adenocarcinoma, Carcinoma, Transitional Cell, Waldenstrom Macroglobulinemia, Papilloma	Altered Intercellular Communication	Diagnoses, in decreasing order of frequency, were nongranulomatous inflammation (321, 85.1%), granulomatous inflammation consistent with sarcoidosis (8, 2.1%), lymphoma (7, 1.9%), papilloma (4, 1.11%), lymphoplasmacytic infiltrate (4, 1.1%), transitional cell carcinoma (2, 0.5%), and single cases of adenocarcinoma, undifferentiated carcinoma, granular cell tumor, plasmacytoma, and leukemic infiltrate.	12918549
Chronic dacryocystitis, Inflammation	Altered Intercellular Communication	Nongranulomatous inflammation consistent with chronic dacryocystitis is the most common diagnosis in lacrimal sac specimens obtained at DCR.	12918549
Inflammation, Myocardial degeneration	Altered Intercellular Communication	Role of inflammation in allogeneic and xenogeneic heart valve degeneration: immunohistochemical evaluation of inflammatory endothelial cell activation.	12918857
Presenile dementia, Communicable Diseases, Inflammation	Altered Intercellular Communication	Inflammation and infectious etiology have been implicated in the pathogenesis of dementia.	12920256
Doctor of Chiropractic, Inflammation	Altered Intercellular Communication	DCM is linked to intramyocardial inflammation, being characterized by T-lymphocytic infiltration and CAMs abundance.	12921808
Inflammation	Altered Intercellular Communication	Joint accumulation of this agent is partly due to specific TNF targeting and is highly predictive for inflammation.	12922953
airway disease, Fibrosis Assessment, Asthma, Occupational, Interstitial inflammation	Altered Intercellular Communication	The authors conclude that occupational exposure of the dental technician to cobalt dust derived from metal dentures may cause chronic airway disease with interstitial inflammation, fibrosis and occupational asthma.	12923999
Pleural Effusion, CTCAE, Inflammation	Altered Intercellular Communication	The pleural effusion might have been due to the inflammation and the disturbed lymphatic drainage caused by the amyloid deposition.	12924508
Inflammation, Ulcer	Altered Intercellular Communication	Histological findings in the gastric mucosa of the ulcer region, however, indicated a significant improvement (P = 0.017) in inflammation scores in OA-R (1.84 +/- 0.41) compared with that in OA-P (2.02 +/- 0.39) after 16-weeks of treatment.	12925153
Inflammation, Ulcer	Altered Intercellular Communication	Rebamipide demonstrated a suppressive effect on the persistent and possibly chronic inflammation in the gastric mucosa of the ulcer region after eradication, but the drug did not improve the eradication rate.	12925153
Inflammation, RTEL1 gene	Altered Intercellular Communication	Although recall bias and selection bias remain potential concerns in our study, the results are generally consistent with the hypothesis that persistent infection/inflammation predisposes individuals to the development of NHL.	12925963
Acute inflammation, Gangrene due to diabetes mellitus	Altered Intercellular Communication	Marked reduction in serum high-density lipoprotein cholesterol concentrations in a woman with acute inflammation due to diabetic gangrene.	12927682
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP) is a well-established, sensitive marker of systemic inflammation and the risk of cardiovascular disease.	12927682
Inflammation, LCN1 gene, Diabetes Mellitus	Altered Intercellular Communication	In acute inflammation and poorly controlled diabetes, CRP is suggested to be inversely associated with serum HDL-C, independent of PG and TP.	12927682
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Inflammation plays an important role in Alzheimer's disease and the inhibition of endothelial nitric oxide by ADMA may increase the concentration of inflammatory mediators in the brain.	12928048
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Various studies suggested that inflammation is involved in the pathogenesis of Alzheimer's disease (AD).	12928049
Data types - Address	Altered Intercellular Communication	These data further support a role for inflammation-related genes in AD or indicate linkage disequilibrium with an unknown chromosome 2 locus.	12928052
Primary malignant neoplasm	Altered Intercellular Communication	Patients with advanced cancer thus exhibit both a high-grade OS and a chronic inflammatory condition.	12928788
Chronic pain in face	Altered Intercellular Communication	This report describes the case of a 73-year-old woman who had gone through an 8-year ordeal involving several paranasal sinus operations, development of chronic facial pain, orbital exenteration of the left eye, and now threatening loss of the remaining right eye on account of progression of the chronic inflammation.	12928811
Inflammation	Altered Intercellular Communication	More than one-third of the false-positive results were due to inflammation.	12929061
Inflammation	Altered Intercellular Communication	About 69 per cent of the children had histopathological evidence of antral inflammation.	12929890
Inflammation, atherosclerotic, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a central role in atherosclerosis since C-reactive protein (CRP), an acute-phase protein monitored as a marker of inflammatory status, has been identified as a major risk factor for atherosclerotic complications.	12931763
Inflammation	Altered Intercellular Communication	A 5-year-old Japanese boy presented with persistent gingival inflammation and severe mobility of the right lower primary incisors.	12931770
Inflammation, Osteopenia	Altered Intercellular Communication	Although inflammation remained around the right primary second molars, the bone loss was controlled by periodic professional mechanical teeth cleaning (PMTC), subgingival irrigation, and local antibiotic application.	12931770
Inflammation, SLC25A20 gene, Atherosclerosis	Altered Intercellular Communication	Measures of inflammation, such as CRP, and indices of atherosclerosis, such as CAC, are likely to provide distinct information regarding cardiovascular risk.	12933535
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Systemic inflammation may play an important part in the development of cardiovascular disease.	12933781
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Systemic inflammation is a potential mediator, especially among young and middle aged men, for the association between socioeconomic status and cardiovascular disease.	12933781
Inflammation, millicurie, Data types - Address	Altered Intercellular Communication	These results demonstrate increased production of the proinflammatory cytokine, TNFalpha and decreased production of the anti-inflammatory cytokine TGFbeta in patients with MCI at risk to develop AD, suggesting a propensity towards inflammation in this patient group and indicating that CNS inflammation is a early hallmark in the pathogenesis of AD.	12933918
Hydrocephalus	Altered Intercellular Communication	"Normal" pressure hydrocephalus (NPH) is associated with injury to neurotransmitter and neuropeptide systems that recovers after surgery.	12933934
Inflammation, With intensity	Altered Intercellular Communication	Magnetic resonance imaging (MRI) of the brain on day 7 showed signal hyperintensity in the central medulla and ventral pons, typical of acute inflammation.	12933947
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The study purpose was the cytooxidant properties of inflammation in patients with severe heterogenic forms of chronic obstructive pulmonary disease (COPD); and the informative value of the changes in the studied indices for assessment of anti-inflammatory efficiency of differential therapy.	12934307
Infarction, Coughing	Altered Intercellular Communication	These infarctions probably induce the disruption of the specific central neurotransmitter system including dopamine and substance P, which plays an important role for swallowing and cough reflex.	12934558
Inflammation, Vasculitis, CTCAE, Acute infectious disease	Altered Intercellular Communication	Monocytes in patients with acute vasculitis displayed a reduced production of oxygen free radicals (P < 0.01) but similar serum concentrations of soluble inflammation markers and adhesion molecules, as compared with the control group of patients with acute infection and negative PR3-ANCA.	12937226
Inflammation	Altered Intercellular Communication	The present study was performed on 21 patients who underwent WBCS for suspected infection/inflammation.	12937949
Inflammation, Asthma	Altered Intercellular Communication	Interleukin-I and interleukin-10 (IL-1 and IL-10) are cytokines that might play a role in the process of inflammation and are therefore considered to be involved in the pathogenesis of bronchial asthma.	12938145
Inflammation	Altered Intercellular Communication	The coved-type ST-segment elevation disappeared as the acute inflammation subsided.	12939560
Inflammation	Altered Intercellular Communication	The airway remodeling is a consequence of changes induced by endothelial cells and extra-cellular matrix as a result of chronic inflammation.	12940105
Inflammation, Psoriasis, Data Type -Character	Altered Intercellular Communication	Our data suggest that bcl-2-mediated inflammation plays a part in the pathogenesis and recurrent character of psoriasis.	12941088
Inflammation, Graft dysfunction	Altered Intercellular Communication	These results suggest that CC is a favorable indication for OLT and that although a proportion of patients develop inflammation in the liver allograft, this does not result in significant graft dysfunction or loss.	12942453
Inflammation	Altered Intercellular Communication	Histological it is characterized by centrolobular necrosis without inflammation.	12942594
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Impact of pathogen burden in patients with coronary artery disease in relation to systemic inflammation and variation in genes encoding cytokines.	12943869
Cerebrovascular accident	Altered Intercellular Communication	These considerations may help to explain why tallness is associated with low stroke risk, whereas growth hormone deficiency increases stroke risk--and why age-adjusted stroke mortality has been exceptionally high in rural Asians eating quasi-vegan diets, but has been declining steadily in Asia as diets have become progressively higher in animal products.	12944100
Inflammation, Thrombosis, Blood Coagulation Disorders	Altered Intercellular Communication	P-selectin is a leukocyte receptor and platelet activation marker that has been shown to be involved in thrombogenesis as well as bleeding disorders and may represent a possible link between inflammation and thrombosis.	12945872
Swelling, Acute inflammation	Altered Intercellular Communication	The eyelids are more susceptible than other tissues to swelling, acute inflammation, and resultant long-term damage.	12946551
Inflammation, Kidney Diseases	Altered Intercellular Communication	Mildly and severely reduced LV EF occurred in 10% and 2% of participants, was associated with older age, male sex, higher systolic pressure, heart rate and markers of renal disease and inflammation.	12947374
Hypercholesterolemia, Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	Results of the studies performed have suggested that hypercholesterolaemia and inflammation are important aetiologic factors in aortic valve stenosis (AVS).	12948037
Cataract, Inflammation	Altered Intercellular Communication	Effectiveness and tolerance of piroxicam 0.5% and diclofenac sodium 0.1% in controlling inflammation after cataract surgery.	12948311
Cataract, Inflammation	Altered Intercellular Communication	These results suggest that piroxicam is as effective as diclofenac sodium in preventing inflammation after cataract surgery with IOL implantation, and its better tolerance and safety can provide higher patient compliance.	12948311
Inflammation, Subretinal route	Altered Intercellular Communication	In the left eye, vitreal inflammation with retinal sheathing and subretinal lesions was predominant.	12948320
Inflammation, Hepatitis C	Altered Intercellular Communication	Expression of the chemokine IP-10 (CXCL10) by hepatocytes in chronic hepatitis C virus infection correlates with histological severity and lobular inflammation.	12949239
Inflammation	Altered Intercellular Communication	IP-10 was expressed by hepatocytes but not by other cell types within the liver, and the most intense immunoreactivity was evident in the areas of lobular inflammation.	12949239
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The expression of IP-10 mRNA correlated with lobular necroinflammatory activity but not with inflammation or fibrosis in the portal tracts.	12949239
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	A marked step-wise increase in Mn-SOD protein levels was observed in non-inflamed and inflamed IBD mucosae, whereas the Cu/Zn-SOD content decreased with inflammation.	12950012
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Disturbances in the carefully orchestrated mucosal antioxidant cascade may contribute to the induction and perpetuation of intestinal inflammation in IBD, and may have important implications for the development of antioxidant treatment of IBD patients.	12950012
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Quantitative measurements showed that in both CD and UC patients, intestinal inflammation was associated with increased activities of CAT, GPO, and MPO, whereas the mucosal GSH content was unaffected and the concentration of MT was decreased.	12950013
Gastrointestinal inflammation	Altered Intercellular Communication	Intestinal inflammation is accompanied by excessive production of reactive oxygen and nitrogen metabolites.	12950014
Cessation of life, Inflammation, Inflammatory Bowel Diseases	Altered Intercellular Communication	Apoptotic cell death was visualized by TUNEL staining in luminal epithelium of normal controls, and in IBD additionally in the inflammatory infiltrate and in deeper parts of the crypts, but its frequency was unrelated to the severity of inflammation.	12950014
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	In Crohn's disease (CD), epithelial apoptosis levels were strongly associated with the expression of XO, implying a role for this enzyme in the regulation of epithelial cell homeostasis, although its levels were unaffected by intestinal inflammation and were comparable to those in normal control mucosa.	12950014
Airway structure, Asthma	Altered Intercellular Communication	Exhaled NO (ENO) has been studied as a noninvasive marker of airway inflammation, and has been shown to be elevated in asthma patients.	12950039
Congestive heart failure	Altered Intercellular Communication	Brain natriuretic peptide (BNP), a neurohormone secreted from the ventricular myocardium in response to hemodynamic load/wall stress, in congestive heart failure (CHF).	12950118
neutrophilic, Inflammation, Angiocentric glioma, Necrosis	Altered Intercellular Communication	Histologically, there is a neutrophilic, angiocentric, segmental inflammation with endothelial cell injury and fibrinoid necrosis of the blood vessel walls.	12950344
Perifolliculitis, Mycoses	Altered Intercellular Communication	In follicular inflammation in diabetics, deep mycosis has to be considered and mycologic diagnostics should be performed before starting any other treatment.	12950910
Inflammation, Ascites	Altered Intercellular Communication	On admission, in addition to elevated serum and urine amylase, plain computed tomography demonstrated a swollen pancreas and high density in the peripancreatic lesion with a large amount of ascites, suggesting the presence of an inflammation of the pancreas as well as peripancreatic lesion.	12951894
Respiratory Tract Infections, Pneumonitis	Altered Intercellular Communication	Balanced secretion of pro- and anti-inflammatory cytokines is essential in limiting pulmonary inflammation in respiratory infections.	12952260
Airway structure, Asthma	Altered Intercellular Communication	Measurement of exhaled nitric oxide (eNO) and analysis of induced sputum are both established noninvasive methods for studying airway inflammation in asthma.	12952273
Inflammation, Infection, Atherosclerosis	Altered Intercellular Communication	Furthermore, new risk concepts of atherosclerosis focusing on inflammation, infections, and immunity have not yet been evaluated in this age group.	12952827
Suppurative inflammation	Altered Intercellular Communication	[Local medical support during surgical treatment of purulent inflammation].	12953406
palladium	Altered Intercellular Communication	This finding emphasises the pathophysiological significance of a disturbed neurotransmitter equilibrium in the rostral brainstem for REM sleep alterations in PD.	12954543
Sporotrichosis, Tumor necrosis, Arthritis	Altered Intercellular Communication	We report a case of disseminated sporotrichosis in a 49-year-old man who was treated with multiple immunosuppressants, including tumor necrosis factor (TNF)-alpha antagonists (etanercept and infliximab), for presumed inflammation arthritis.	12955647
Inflammation, Infestation by Demodex, Immunocompromised Host	Altered Intercellular Communication	Demodex infestation can cause dramatic facial and eyelid inflammation in immunocompromised patients.	12956690
Inflammation, Candidiasis	Altered Intercellular Communication	A case of chronic inflammation complicated by Candida infection of the parotid gland in a 50-year-old woman is presented.	12956927
Inflammation, Infection, Chronic disease	Altered Intercellular Communication	This result considered that procalcitonin could be a good indicator of inflammation in patients with chronic diseases and in persons exposed to long-lasting infections.	12957529
Inflammation, Coronary heart disease	Altered Intercellular Communication	This may indicate a coordinated state of pro-inflammatory upregulation with widespread activation of both leukocytes and endothelium and suggests a systemic rather than local source for inflammation in acute coronary disease.	12957758
Airway structure, Increase	Altered Intercellular Communication	We hypothesize that a possible increase in breath CO caused by airway inflammation might be masked by differences in lung volumes between control subjects and patients with CF.	12958053
Inflammation, Restenosis	Altered Intercellular Communication	When analyzed separately, none of the polymorphisms was associated either with inflammation or restenosis.	12958619
Inflammation, Obesity	Altered Intercellular Communication	Gender influences the association of certain inflammatory variables with BMI so the sexes should be considered separately in studies of inflammation and obesity.	12960611
Osteogenesis, Inflammation, Dystrophic calcification, Ruptured simple cyst	Altered Intercellular Communication	Cyst rupture with mucin dissection into the stroma, inflammation, and dystrophic calcification with ossification were common.	12960806
Parkinson Disease	Altered Intercellular Communication	Cyclic exercise induces anti-inflammatory signal molecule increases in the plasma of Parkinson's patients.	12964024
Thyroid Diseases, Inflammation	Altered Intercellular Communication	C-reactive protein (CRP) levels have not been routinely used to diagnose thyroid disease, although many thyroid conditions involve inflammation.	12964969
Inflammation, Osteopenia	Altered Intercellular Communication	ADAM8 is (over)expressed in tissues around aseptically loosened total hip implants, which are characterized by chronic foreign body inflammation and peri-implant bone loss.	12966612
Conjunctivitis	Altered Intercellular Communication	Acute conjunctival inflammation following contact with squashed spider contents.	12967822
Inflammation, herpesvirus 3, human	Altered Intercellular Communication	Serum antibody of varicella-zoster virus (VZV) was increased, and Gd enhanced MR imaging demonstrated an enhancement of a geniculate ganglion of the left facial nerve, indicating inflammation.	12968493
Inflammation, Portal tract inflammation, Fatty degeneration, Hepatitis	Altered Intercellular Communication	There were weaker but significant associations between the proportion of hepatocytes expressing Mcm-2 and inflammatory indices including interface hepatitis, portal tract inflammation, lobular inflammation and steatosis.	12969185
Inflammation, Dyslipidemias, Venous Thromboembolism, vinyltriethoxysilane	Altered Intercellular Communication	Venous thromboembolism (VTE) involves inflammation and a relation with dyslipidemia which remains controversial.	12969812
Pneumonitis	Altered Intercellular Communication	Bland-Altman analysis showed a good agreement for eosinophil and neutrophil counts when techniques A and B were compared to technique C. The three techniques are good indicators of lung inflammation.	12970038
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Compared with normal controls, plasma sCD40L levels were significantly higher in both CD and UC patients and proportional to the extent of mucosal inflammation.	12970136
Inflammation	Altered Intercellular Communication	On the other hand, EN did not simulate the excretion of pancreas and avoid exaggerating the inflammation of pancreas.	12970916
Inflammation, Squamous cell carcinoma, Epithelial cyst	Altered Intercellular Communication	In conclusion, atypical keratinocytes in the lowermost portion of the cyst wall were deemed to be secondary to inflammation due to treatment by a surgeon rather than to development of both in situ and invasive squamous cell carcinomas in an epidermoid cyst.	12971267
Inflammation, Thrombosis, Dental Plaque	Altered Intercellular Communication	However, the step I diet did not significantly change serologic markers of inflammation, plaque stability, and thrombosis.	12972113
Ocular histoplasmosis syndrome, Unknown (origin) (qualifier value), Inflammation	Altered Intercellular Communication	The cause of CNV was idiopathic (nine eyes), age-related macular degeneration (six eyes), presumed ocular histoplasmosis syndrome (one eye), and inflammation (one eye).	12972756
Rupture, Inflammation, Neoplasms	Altered Intercellular Communication	F-18 FDG positron emission tomographic imaging in a case of ruptured breast implant: inflammation or recurrent tumor?	12972998
Inflammation, Neoplasms	Altered Intercellular Communication	It is well-known that fluorodeoxyglucose (FDG) is taken up by different tumors and active inflammation.	12973015
Inflammation, Neoplasms	Altered Intercellular Communication	Study design Fifty-two patients with tumors or inflammation in the oral and maxillofacial region underwent (67)Ga scanning.	12973295
Gastrointestinal inflammation, Clostridium difficile colitis	Altered Intercellular Communication	FL positivity in IUC may depend on the intestinal inflammation precipitated by C. difficile infection.	12974208
Inflammation, Disease	Altered Intercellular Communication	These differences were also observed with purified lamina propria (LP) T cells in both diseases and were associated with the presence of inflammation.	12974764
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The absolute or relative defect in TGF-beta1 production observed in CD and UC may contribute to the perpetuation of inflammation.	12974764
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Inflammation promotes acute coronary syndromes and ensuing clinical complications.	12975259
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	High-dose atorvastatin potentiated the decline in inflammation in patients with acute coronary syndromes.	12975259
Myocarditis	Altered Intercellular Communication	Five days after the procedure the patient developed signs and symptoms of the post-pericardiotomy syndrome and showed new, intense pericardial inflammation on magnetic resonance imaging.	12975573
Inflammation, Hyphae, Necrosis, Granuloma	Altered Intercellular Communication	Directed lung biopsies showed chronic inflammation, necrosis, or granulomas without hyphal invasion.	12975754
Granulomatous inflammation, Occluded, Necrosis	Altered Intercellular Communication	Histopathologic analysis of eyelid biopsy specimens showed granulomatous inflammation, focal necrosis, and areas of occlusive vasculitis in the tarsus and conjunctiva.	13129876
Inflammation, Conjunctival Diseases	Altered Intercellular Communication	Tarsal-conjunctival disease, a previously uncommon finding in patients with WG, was characterized by inflammation of the palpebral conjunctiva and tarsus followed by a fibrovascular proliferation and scar formation.	13129876
Neurogenic Inflammation, Hypersensitivity	Altered Intercellular Communication	Substance P (SP) and Vasoactive Intestinal Peptide (VIP) neuropeptides play a role in the immediate and late type of hypersensitivity as well as in neurogenic inflammation.	13130168
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Doppler ultrasound and magnetic resonance imaging of synovial inflammation of the hand in rheumatoid arthritis: a comparative study.	13130462
Inflammation	Altered Intercellular Communication	There was a highly significant association between US indices of inflammation and postcontrast MRI scores.	13130462
Inflammation, Morning stiffness - joint, Pain Distress Question	Altered Intercellular Communication	No association between the MRI or US estimates of inflammation and values on the visual analog scale for pain, Health Assessment Questionnaire, duration of morning stiffness, ESR, or CRP was found.	13130462
Inflammation, Hemorrhage	Altered Intercellular Communication	Studies in animal models have shown perimicrovascular hemorrhages and inflammation after sustained systemic immunizations in animals with vascular amyloid.	13130516
Inflammation, Granuloma	Altered Intercellular Communication	In the choroid, diffuse granulomatous inflammation which could be called "silicone oil granuloma" was observed.	13677297
Seizures, Convulsions in the newborn	Altered Intercellular Communication	Despite the fact that two disorders associated with neonatal seizures are diagnosed by cerebrospinal fluid neurotransmitter analysis, such an analysis is not standard in the work-up for idiopathic neonatal seizures.	13677584
Convulsions in the newborn	Altered Intercellular Communication	This case illustrates the importance of cerebrospinal fluid neurotransmitter analysis as part of the work-up for idiopathic neonatal seizures.	13677584
Inflammation, Carcinoma of lung, Bronchial Fistula	Altered Intercellular Communication	Conservative therapy under nutritional management mainly consisting of central venous nutrition may be useful for some surgically treated lung cancer patients with bronchial stump fistula when they have mild inflammation and the reduction of pyrothorax cavity can be expected by re-expansion of the residual lobes of the lung.	13677917
Glaucoma, CTCAE	Altered Intercellular Communication	Our findings of increased expression of 3alpha-HSDs in glaucomatous optic nerve head astrocytes offer new insights into possible roles for neurosteroids in the pathophysiology of glaucoma.	13678667
Inflammation, Cross Infection, septic	Altered Intercellular Communication	The imbalance between the bioactive and regulatory IL-12 isoforms, which is probably designed to control excessive inflammation, may also make septic patients more susceptible to nosocomial infection.	13679443
Airway structure, Bronchoconstriction, Acute asthma	Altered Intercellular Communication	Thus C3a may be related to airway inflammation and bronchoconstriction in acute asthma exacerbation.	13679811
Airway structure, Asthma, Bronchoconstriction	Altered Intercellular Communication	Concentrations of C3a, which can induce airway inflammation and bronchoconstriction, were associated with differences in response to emergency treatment of severe asthma exacerbation.	13679811
Vasculitis, Glaucoma, CTCAE	Altered Intercellular Communication	In the left eye he had 20/20 vision but showed signs of retinal vascular inflammation and secondary glaucoma.	13680252
Inflammation	Altered Intercellular Communication	led to complete regression of the acute inflammation within 2 weeks prior to operation.	13680252
Inflammation	Altered Intercellular Communication	There was no intra- or perioperative recurrence of inflammation, which is a common finding in these procedures.	13680252
Systolic dysfunction, Congestive heart failure	Altered Intercellular Communication	In clinically stable patients with CHF and severe systolic dysfunction, BNP is the only neurohormone sensitive to the concomitant presence of a restrictive pattern.	13680551
Helminths, Gastrointestinal inflammation	Altered Intercellular Communication	The study suggests that it is possible to downregulate aberrant intestinal inflammation in humans with helminths.	14499784
Communicable Diseases, Inflammation	Altered Intercellular Communication	An extensive hematologic evaluation for infection and inflammation was negative.	14499821
Inflammation	Altered Intercellular Communication	The role of inflammation in intracranial large-artery occlusive disease is unclear.	14500938
Inflammation	Altered Intercellular Communication	These findings are consistent with the hypothesis that inflammation may be involved in the progression and complication of intracranial large-artery occlusive disease.	14500938
Inflammation, Granuloma	Altered Intercellular Communication	Gross examination of the surgical specimen revealed transmural inflammation, deep ulcerations and non-necrotizing epithelioid cell granuloma.	14501622
Osteitis	Altered Intercellular Communication	Both magnetic resonance imaging and technetium bone scanning are sensitive for localizing occult sites of bone inflammation.	14501940
Inflammation, Acute Coronary Syndrome, Nonstress test, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	To evaluate the performance of the turbidimetric method of C-reactive protein (CRP) as a measure of low-grade inflammation in patients admitted with non-ST elevation acute coronary syndromes (ACS).	14502382
Inflammation, Data types - Address	Altered Intercellular Communication	Altogether, our data suggest a link between inflammation and the compromised cerebral hemodynamics in AD.	14503019
Hypercholesterolemia, Inflammation	Altered Intercellular Communication	This study suggests that platelets might contribute to IL-1beta production in hypercholesterolemia, thus providing an additional link between inflammation and the prothrombotic state in this setting.	14504184
Inflammation, Thickened, Vascular System Injuries	Altered Intercellular Communication	In the same region, only minimal vascular injury (thickening of some of the capillary walls) was detected, but not cell proliferation or chronic inflammation.	14504618
Inflammation	Altered Intercellular Communication	Although low-grade inflammation was associated with long QTc interval and low HDL-cholesterol, the mechanism underlying these associations is an important question to be addressed.	14506615
Inflammation, Primary malignant neoplasm, Diabetes Mellitus	Altered Intercellular Communication	Angiogenesis is an essential biological process not only in embryogenesis, but also in the progression of several major diseases, including cancer, diabetes, and inflammation.	14506635
Inflammation	Altered Intercellular Communication	Vascular density was significantly higher in the cases showing chronic inflammation (P = 0.007).	14506635
Inflammation, Obesity	Altered Intercellular Communication	Relationship between obesity and serum markers of oxidative stress and inflammation in Japanese.	14507248
Inflammation, Coronary heart disease, Obesity, Choline Dehydrogenase, Mitochondrial, Malignant Neoplasms	Altered Intercellular Communication	In conclusion, obesity is highly associated with states of oxidative stress and low-grade inflammation in Japanese residents, suggesting that these latter might play an important role in the association between a high BMI and certain cancers as well as coronary heart disease (CHD).	14507248
Inflammation	Altered Intercellular Communication	Thus, our results indicate a heterogeneous group of TAO diseases, suggesting that damage to elastic fibers may be a secondary change to primary inflammation.	14507318
Intestinal metaplasia, Inflammation, Chronic gastritis	Altered Intercellular Communication	Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasia, and chronic inflammation.	14507661
Intestinal metaplasia, Inflammation, Helicobacter pylori	Altered Intercellular Communication	The present study attempted to compare the methylation status of nonneoplastic gastric mucosa, using clinicopathological parameters, including age, gender, Helicobacter pylori (H. pylori), acute and chronic inflammation, and intestinal metaplasia.	14507661
Intestinal metaplasia, Inflammation, Gastric mucosa	Altered Intercellular Communication	Our results demonstrated that many genes are methylated in the stomach as a function of age, and suggested that male gender, intestinal metaplasia, and chronic inflammation are closely associated with increased methylation in nonneoplastic gastric mucosa samples.	14507661
Inflammation, Corneal Ulcer	Altered Intercellular Communication	The main outcome measures were wound healing of the corneal ulcers and decrease of stromal inflammation.	14507749
Inflammation, Keratitis, Herpetic, Ulcer	Altered Intercellular Communication	Although performed in an uncontrolled and non-randomised series of patients, these findings indicate that the AMT shows promise in selected cases for the restoration of ocular surface integrity, reduction of stromal inflammation, and improvement of vision in acute ulcerative and necrotising herpetic keratitis.	14507749
Pancreatitis, Acute, Inflammation	Altered Intercellular Communication	In patients with acute pancreatitis, plasma concentrations of CTpr appear to reflect more closely the derangement in gut barrier function rather than the extent of systemic inflammation.	14508129
Inflammation, Fibrosis Assessment, Muscle hypertrophy, Epithelial metaplasia	Altered Intercellular Communication	The following histologic features were evaluated: degree of mucosal and deep inflammation, lymphoid nodules, epithelial metaplasia, muscular hypertrophy, Rokitansky-Aschoff sinuses, fibrosis, and cholesterolosis.	14508392
Chronic cholecystitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Gallbladders in malignancy-associated obstructive jaundice were nearly identical to gallbladders in PSC with respect to scores for mucosal inflammation, lymphoid nodules, and frequency of diffuse lymphoplasmacytic chronic cholecystitis (60% vs. 50%, respectively).	14508392
Inflammation, Cholelithiasis, Fibrosis Assessment, Muscle hypertrophy	Altered Intercellular Communication	The cholelithiasis control group was characterized by lack of significant mucosal inflammation in the majority of cases (95%) and frequent Rokitansky-Aschoff sinuses, fibrosis, and muscular hypertrophy.	14508392
Keratitis	Altered Intercellular Communication	In vivo confocal microscopy in the acute phase of corneal inflammation.	14509473
Keratitis	Altered Intercellular Communication	Further analysis in a large number of patients may aid in further understanding in vivo human corneal inflammation.	14509473
Human papilloma virus infection, Rupture, Inflammation	Altered Intercellular Communication	In this instance, EV-associated HPV infection of the follicular infundibular epithelium or pre-existing cysts in the setting of immunodeficiency may have led to cystic growth, rupture and subsequent painful inflammation.	14511000
Inflammation	Altered Intercellular Communication	In particular COX-2 was demonstrated to be crucial for PG-synthesis in inflammation.	14511332
Inflammation	Altered Intercellular Communication	The systemic inflammatory response is associated with increased lipid peroxidation and low carotenoid concentrations indicating that inflammation driven breakdown of carotenoids is an important factor in lowering circulating carotenoid concentrations in the critically-ill patient.	14512033
Inflammation, Dysplasia, Carcinoma, Neoplasms	Altered Intercellular Communication	The histological examination showed normal tissue in 850 cases, in 55 cases scarring or inflammation, in 62 meta- or dysplasias, in 11 carcinomas in situ and in 127 invasive tumors.	14512675
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Our results suggest that inflammation may be closely related to the mechanism of type 2 diabetes among Japanese Americans.	14514575
Inflammation, Albuminuria, Diabetes Mellitus, Non-Insulin-Dependent, Ventricular hypertrophy	Altered Intercellular Communication	Relation of left ventricular hypertrophy to inflammation and albuminuria in adults with type 2 diabetes: the strong heart study.	14514577
Left Ventricular Hypertrophy, Inflammation, Disease of capillaries, Electrocardiogram: left ventricle hypertrophy (finding), Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	To evaluate in adults with type 2 diabetes the extent to which the relation of left ventricular hypertrophy (LVH) to markers of systemic inflammation (fibrinogen and high-sensitivity C-reactive protein [hsCRP]) are affected by microangiopathy.	14514577
Left Ventricular Hypertrophy, Thrombosis, Inflammation, Albuminuria, Diabetes Mellitus, Non-Insulin-Dependent, Endothelial dysfunction, Disease of capillaries	Altered Intercellular Communication	In adults with type 2 diabetes, echocardiographic LVH is associated with susceptibility to atherothrombosis and increased albuminuria, which is a marker of microangiopathy and endothelial dysfunction that appears in turn to be a relevant pathogenetic link between LVH and inflammation.	14514577
Microalbuminuria, Left Ventricular Hypertrophy, Inflammation, Albuminuria	Altered Intercellular Communication	However, in the absence of significant microalbuminuria, elevated BMI is a relevant pathogenetic factor in the relation of LVH to increased levels of markers of inflammation, potentially preceding development of significant albuminuria.	14514577
Polycystic Kidney, Autosomal Dominant, Fibrosis Assessment, Kidney Failure, Interstitial inflammation	Altered Intercellular Communication	Autosomal dominant polycystic kidney disease (ADPKD) progresses to renal insufficiency in >50% of patients and is characterized by interstitial inflammation and fibrosis in the end stage.	14514736
eosinophil, Asthma, Airway structure	Altered Intercellular Communication	The study demonstrates a relationship between reduced sputum eosinophil apoptosis and increased clinical severity of chronic stable asthma, providing additional evidence that eosinophil apoptosis may be important in the resolution of eosinophilic airway inflammation in asthma.	14516139
Inflammation	Altered Intercellular Communication	Furthermore in eyes already predisposed to inflammation through prior surgery and/or presence of PVR, the inflammatory effects were not insignificant.	14516428
Pituitary Apoplexy, Hypopituitarism	Altered Intercellular Communication	She then developed pituitary apoplexy followed by hypopituitarism, as confirmed by hormonal measurements.	14518145
Inflammation, Edema	Altered Intercellular Communication	Tissue samples were graded for degree of inflammation and edema.	14520093
Inflammation, Edema	Altered Intercellular Communication	Polyp tissue from the ASA sensitive patients demonstrated more edema and more inflammation on average than ASA tolerant polyps, but the results were not statistically significant.	14520093
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	In the present study, we measured the serum concentration of IL-18 and other markers of inflammation in 35 patients with acute coronary syndrome.	14520485
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	This suggests that CRP may contribute to the mechanism of coronary artery disease in addition to being an incidental product of various types of systemic inflammation.	14520485
Hashimoto Disease, Inflammation, Hypothyroidism	Altered Intercellular Communication	High titres of antiperoxidase and antithyroglobulin antibodies with normal levels of TSH receptor antibodies, in addition to biological hypothyroidism and lymphocytic inflammation were consistent with the diagnosis of Hashimoto's thyroiditis.	14520579
Kidney Failure, Chronic, Anemia	Altered Intercellular Communication	Elements of malnutrition-inflammation complex syndrome (MICS) may blunt the responsiveness of anemia of end-stage renal disease (ESRD) to recombinant human erythropoietin (EPO).	14520627
Inflammation, Asthma	Altered Intercellular Communication	We conclude that assessment of inflammation or the anti-inflammatory effects of drugs in asthma based on single determinations of FE(NO) can be misleading.	14520724
Steatohepatitis, Adenoma, Glycogen Storage Disease	Altered Intercellular Communication	Other prominent findings included steatohepatitis and nonspecific granulomatous inflammation--2 findings that are commonly seen in sporadic adenomas but not, to our knowledge, previously reported in glycogen storage disease type Ia.	14521443
Traumatic injury	Altered Intercellular Communication	Acquired syndactyly is a rare disease that occurs mostly after disease, trauma, or other inflammatory conditions.	14521704
Inflammation, Cerebral Infarction	Altered Intercellular Communication	In the cerebral infarction groups, the level of IL-6 was higher than that in the normal population, indicating that these can be resulted from local inflammation and immunity reactivity.	14521778
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Increasing evidence supports a role for inflammation in chronic heart failure (CHF).	14522416
Inflammation, Cognition Disorders	Altered Intercellular Communication	PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation.	14523101
Inflammation, Impaired cognition	Altered Intercellular Communication	In many of these models, however, the temporal development of cognitive decline and the relationship to Abeta deposition and inflammation are unclear.	14523101
Inflammation, Cognition Disorders	Altered Intercellular Communication	Cognitive deficits were first observed at 8 months when Abeta deposits and inflammation were restricted to discrete brain regions, namely the subiculum and frontolateral (motor and orbital) cortex.	14523101
Inflammation	Altered Intercellular Communication	Despite considerable improvement in inflammation and function scores, only 31 (26%) patients were in remission at 1 yr with 20 (21%) in remission at 2 yr.	14523223
Inflammation, Diabetes Mellitus, Insulin-Dependent, Vascular Diseases	Altered Intercellular Communication	According to our results, AFP, a known marker of low-grade chronic inflammation, are increased in patients with type 1 diabetes probably independently of glycemic control and the presence of clinical microvascular or macrovascular disease.	14526268
Inflammation	Altered Intercellular Communication	Chronic inflammation and obstruction of the lower urinary tract might be the causes for proliferative lesions of the bladder.	14526439
Mycobacterium Infections, Caseous necrosis, Granulomatous inflammation	Altered Intercellular Communication	Cytologic features of mycobacterial infections are granulomatous inflammation with or without caseous necrosis and the demonstration of acid-fast bacilli with special stains.	14526677
Inflammation, Inflammatory disorder	Altered Intercellular Communication	The expression of C5aR in synoviocytes from inflammatory joint diseases and also the induction of TNF alpha release in activated synoviocytes by the interaction of C5a and C5aR suggest that the C5a/C5aR system may play an important role in joint inflammation process.	14527377
Inflammation	Altered Intercellular Communication	Positron emission tomography (PET) imaging with 18-fluorodeoxyglucose (FDG) can rapidly provide anatomically clear images and define areas of inflammation with increased glucose metabolism.	14528383
Inflammation, Urethritis, Decrease in height	Altered Intercellular Communication	Significantly associated factors for worse MRS were height loss (+), sex (higher MRS in males), active inflammation of the cervical region (+), age (+), maximum height (-), active inflammation of the hip region (+), involvement of shoulders (+), time since first AS symptoms (+), urethritis (-), regular practice of sports (-), involvement of feet (-), and hip replacement (+).	14528516
Granulomatous inflammation	Altered Intercellular Communication	Skin biopsy revealed granulomatous inflammation and anti-tuberculosis treatment was started empirically but stopped 2 months later owing to a poor response.	14528880
Granulomatous inflammation	Altered Intercellular Communication	A right supraclavicular lymph node was aspirated and revealed granulomatous inflammation.	14528880
Communicable Diseases, Malignant Neoplasms, Granulomatous inflammation	Altered Intercellular Communication	Fibreoptic bronchoscopy showed no endobronchial lesion but the transbronchial biopsy showed granulomatous inflammation with no evidence of infection, malignancy or foreign body.	14528880
Granulomatous inflammation, Infiltration	Altered Intercellular Communication	Pathologic examination revealed granulomatous inflammation, with lymphocyte and giant cell infiltration.	14530649
Stomatitis	Altered Intercellular Communication	Inflammation of gastric and duodenal mucosa as well as alkali used may significantly decrease calcium absorption.	14530909
Inflammation	Altered Intercellular Communication	Additionally, bone metabolism may be changed by inflammatory mediators released as a result of mucosal inflammation.	14530909
Communicable Diseases, Inflammation, Arthritis, Infectious	Altered Intercellular Communication	Septic arthritis--infection with resulting inflammation within a joint--is an emergency.	14531208
Aneurysm, Inflammation	Altered Intercellular Communication	Histological findings in specimens of the resected aneurysm suggested that tuberculous inflammation of the surrounding lymph nodes had invaded the aortic wall, leading to the aneurysm.	14531306
Inflammation	Altered Intercellular Communication	Inflammation scores were lower in both the JPI and RY groups than in the B-I and B-II groups (P < 0.05, respectively).	14531528
Inflammatory abnormality of the eye	Altered Intercellular Communication	To evaluate the clinical experience with methotrexate as a first-line corticosteroid-sparing drug in patients with resistant ocular inflammation.	14533032
Inflammation	Altered Intercellular Communication	A differential approach to choice of surgical method with consideration of the degree, phase and localization of inflammation is preferable.	14533379
Granuloma	Altered Intercellular Communication	Granuloma faciale (GF) is an uncommon inflammatory condition characterized by reddish brown papules and plaques that usually involve the facial area.	14533833
Microvascular Angina, hormone deficiency, Hypopituitarism	Altered Intercellular Communication	A coroner's autopsy conducted on an 11.5-year-old girl, with a history of hypopituitarism, manifesting as growth hormone deficiency associated with short stature, demonstrated the presence of an undiagnosed hypothalamic intracranial germinoma, showing hypophyseal and mesencephalic invasion, together with histological evidence of microvascular (small coronary artery) disease of the heart.	14550605
Pneumonitis	Altered Intercellular Communication	Exhaled breath condensate detects markers of pulmonary inflammation after cardiothoracic surgery.	14551168
airway disease, Inflammation	Altered Intercellular Communication	Analysis of mediators in exhaled breath condensate is a promising means of monitoring inflammation in a variety of airway diseases but the contribution of the airway lining fluid from the lower respiratory tract is uncertain.	14551168
Communicable Diseases, Inflammation, Fever, CTCAE	Altered Intercellular Communication	Clinical value of FDG PET in patients with fever of unknown origin and patients suspected of focal infection or inflammation.	14551752
Communicable Diseases, Inflammation, Fever, CTCAE, Fever of Unknown Origin	Altered Intercellular Communication	Fever of unknown origin (FUO) and suspected focal infection or inflammation are challenging medical problems.	14551752
Communicable Diseases, Inflammation, Fever of Unknown Origin	Altered Intercellular Communication	All FDG PET scans ordered because of FUO or suspected focal infection or inflammation in the last 4 years were reviewed.	14551752
Communicable Diseases, Inflammation	Altered Intercellular Communication	Fifty-five FDG PET scans were performed in 48 patients with suspected focal infection or inflammation.	14551752
Communicable Diseases, Inflammation	Altered Intercellular Communication	The positive predictive value of FDG PET in these 55 episodes of suspected infection or inflammation was 95% and the negative predictive value was 100%.	14551752
Communicable Diseases, Inflammation, Fever of Unknown Origin	Altered Intercellular Communication	It is concluded that FDG PET appears to be a valuable imaging technique in the evaluation of FUO and suspected focal infection or inflammation.	14551752
Inflammation	Altered Intercellular Communication	These abnormalities in cell character might be caused by the specific circumstances of PAL lymphomagenesis, i.e., chronic inflammation.	14556658
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Thus, PAL cell lines could be useful in analysis of molecular mechanisms leading to malignancy in chronic inflammation.	14556658
Necrotizing granulomatous inflammation	Altered Intercellular Communication	The development of granulomatous vascular inflammation in this patient with less than 200 CD4 cells/microl might have been due to immune overactivation.	14556759
Inflammation, Hyperglycemia, Atherosclerosis	Altered Intercellular Communication	Inflammation, indicated by hs-CRP, and hyperglycemia, indicated by HbA1c, jointly contribute to the cardiovascular risk of patients with advanced atherosclerosis.	14557362
Inflammation, Muscle, Smooth, Vascular, Atherosclerosis	Altered Intercellular Communication	Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis.	14557365
vascular inflammations	Altered Intercellular Communication	Introduction of Ras into the arteries enhanced vascular inflammation and senescence compared with mock-infected injured arteries.	14557365
vascular inflammations	Altered Intercellular Communication	Our results suggest that atherogenic stimuli mediated by Ras induce VSMC senescence and vascular inflammation, thereby contributing to atherogenesis.	14557365
Infarction, Ischemia, Inflammation	Altered Intercellular Communication	Thereby, nervelets can be seen to survive the hyperacute phase of ischemia, but may be in part damaged by the successive granulocytic-macrophage inflammation enzyme lysis of the infarcted muscle.	14558295
Inflammation, Vessel perforation	Altered Intercellular Communication	Transmural coronary inflammation triggers simultaneous multivessel rupture of unstable plaques.	14558302
Inflammation, Dental Plaque, Rupture	Altered Intercellular Communication	In conclusion, the present case report confirms the hypothesis that inflammation plays a key role in the onset of acute coronary syndromes as it promotes the formation of an unstable plaque as well as its rupture.	14558302
Inflammation	Altered Intercellular Communication	Of the 61 patients, four reported eye inflammation/infection during the treatment.	14558855
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	In 80.2% of patients, portal inflammation was present, and 9.4% had cirrhosis.	14561231
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	The amount of increase in liver enzymes bore no relationship with fibrosis, portal inflammation, and degree of steatosis.	14561231
Cholestasis, Portal inflammation	Altered Intercellular Communication	A liver biopsy revealed severe cholestasis and mild portal inflammation.	14561576
Osteomyelitis, Inflammation	Altered Intercellular Communication	STIR imaging is highly effective for the evaluation of bone marrow and surrounding soft tissue in terms of the detection of osteomyelitis in the mandible and the identification of inflammation spreading to soft tissue.	14561978
Intestinal metaplasia, Inflammation, Epithelial Damage, Atrophic	Altered Intercellular Communication	Variables analysed included chronic inflammation, inflammatory activity, atrophy, intestinal metaplasia, H pylori, surface epithelial damage.	14562384
Inflammatory disease of mucous membrane, Duodenal Ulcer, Gastric Ulcer, CTCAE 5, Peptic Ulcer, Chronic gastritis	Altered Intercellular Communication	cagG was amplified by polymerase chain reaction in 145 H pylori isolates cultured from patients with chronic gastritis (n=72), duodenal ulcer (n=48), gastric ulcer (n=17), or gastric and duodenal ulcer (n=8), and the relationship between cagG status and the grade of gastric mucosal inflammation was determined.	14562388
Inflammation, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The average grade of gastric mucosal inflammation in the antrum and corpus was 1.819+/-0.325 and 1.768+/-0.312, respectively in cagG positive patients, whereas the average inflammation grade was 1.649+/-0.297, 1.598+/-0.278 respectively in cagG negative cases (P>0.05).	14562388
Inflammatory disease of mucous membrane	Altered Intercellular Communication	cagG status was not related to clinical outcome or the degree of gastric mucosal inflammation.	14562388
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	To demonstrate that nitroglycerin improves biological markers of arterial inflammation in patients with peripheral vascular disease.	14564337
Inflammation, Inflammatory disorder, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is an inflammatory disease in which there is an increase in active inflammation markers such as C-reactive protein and other factors released by endothelial cells.	14564337
Inflammation, Asthma	Altered Intercellular Communication	The chronic inflammation of bronchial asthma is characterized by swelling of the subepithelial mucosa.	14565685
Tissue damage, Inflammation, Communicable Diseases	Altered Intercellular Communication	Proinflammatory cytokines (IL-1beta, IL-6, TNF-alpha) are excellent predictive factors of tissue damage, inflammation and infection.	14565910
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	Histological examination revealed a granulomatous inflammation, fitting to sarcoidosis, which was verified in the same year by mediastinoscopy.	14566665
Amenorrhea, Hyperprolactinemia	Altered Intercellular Communication	Hyperprolactinemia is the most frequently seen alteration in their hormonal profile with the highest concentrations in those with secondary amenorrhea.	14567093
Inflammation	Altered Intercellular Communication	The evacuants observed at that time contained numerous leukocytes but no microorganisms, suggesting intensified inflammation as the likely cause of deterioration.	14567605
Inflammation, Postoperative Period	Altered Intercellular Communication	Some fusobacterial brain abscesses may be associated with a paradoxical postoperative deterioration, which is probably due to intensified inflammation following treatment.	14567605
Icterus, Inflammation, Cholestasis, Necrosis	Altered Intercellular Communication	Liver biopsies from the jaundiced patients were similar, with cholestasis, duct necrosis, and extravasation of bile, ductular proliferation, and portal inflammation.	14567716
Inflammation, Xanthogranulomatous salpingitis	Altered Intercellular Communication	However, this lesion may share pathogenetic similarities with xanthogranulomatous salpingitis, since both processes are mediated by inflammation.	14567739
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation plays an important role in cardiovascular disease.	14568895
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	The aim of this study was to determine whether biochemical markers for inflammation could prove effective in identifying the most appropriate patients with suspected inflammatory bowel disease (IBD) for labelled white cell scanning.	14569168
Refractory anemias, Inflammation	Altered Intercellular Communication	These results indicate that sex steroid receptors are present in RA and non-inflamed synovial tissues, including inflammatory cells in RA, and suggest that sex steroids may play important roles in the regulation of inflammation of RA synovial tissue.	14570589
Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	This is provocative given reports of the possible role of inflammation in these two neurodegenerative disorders.	14570706
Inflammation, Autoimmune Chronic Hepatitis	Altered Intercellular Communication	We have demonstrated that Fas expression is detected in hepatocytes of the liver with autoimmune hepatitis and that the level of Fas expression reflects the severity of inflammation in autoimmune hepatitis.	14571717
Inflammation, Fibrosis Assessment, Cholestasis	Altered Intercellular Communication	Liver biopsy demonstrated diffuse ongoing advanced chronic cholestasis, moderate portal and periportal inflammation as well as bridging fibrosis.	14571732
Inflammation	Altered Intercellular Communication	At the prospective evaluation, the chronic inflammation showed a significant progressive worsening over time (p = 0.011).	14571740
Architectural Distortion, Mucosal erosion, Inflammation	Altered Intercellular Communication	Histologic features (mucosal erosion, distortion of crypt architecture, inflammation and lamina propria gap) significantly improved in all treated patients.	14571743
Mental disorders	Altered Intercellular Communication	Autoantibodies to neurotransmitters in a wide spectrum of psychiatric disorders have not previously been reported.	14572623
Inflammation, Pelvic Pain, prostatitis	Altered Intercellular Communication	Prostatitis NIH IIIB is defined by chronic pelvic pain without evidence of inflammation in prostate secretions or ejaculate.	14572752
Inflammation, Vascular System Injuries	Altered Intercellular Communication	Inflammation is the primary response to vessel wall injury caused by stent placement in coronary arteries.	14572794
Communicable Diseases, Periodontitis, Inflammation	Altered Intercellular Communication	Chronic periodontitis (CP) is caused by enhanced resorption of the alveolar bone supporting the teeth and is associated with intraoral inflammation after infection with certain bacteria.	14572874
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Inflammation is linked to adverse outcomes in acute coronary syndromes.	14573731
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Numerous lines of evidence suggest mechanistic links between myeloperoxidase and both inflammation and cardiovascular disease.	14573731
Acute Coronary Syndrome, Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	In severe acute coronary syndromes (ACS) elevation of markers of inflammation and acute phase reaction (APR) like C-reactive protein (CRP) as well as a release of troponin have been reported.	14574074
Inflammation, Angina Pectoris	Altered Intercellular Communication	In stable angina pectoris, markers of inflammation and coagulation were slightly elevated (p < 0.05).	14574074
Inflammation, Skin Diseases, Parasitic	Altered Intercellular Communication	This parasitic skin disease is almost invariably associated with intense inflammation around embedded fleas, the underlying mechanisms being unknown.	14574559
Inflammation	Altered Intercellular Communication	Secondly, an early punction of the knee joint should be carried out if there is any doubt regarding inflammation.	14574603
Hemorrhagic inflammation	Altered Intercellular Communication	The mass was composed of necrotizing hemorrhagic inflammation that contained free-living amebae.	14575235
Granuloma, Hemorrhagic inflammation, Necrosis	Altered Intercellular Communication	2) It had central necrotic and hemorrhagic inflammation that contained acute and chronic inflammatory cells without granulomas or eosinophils.	14575235
Granulomatous inflammation	Altered Intercellular Communication	Fourteen of 15 tissue-biopsy specimens from suspicious sites revealed granulomatous inflammation.	14575282
Inflammation, Tissue injury	Altered Intercellular Communication	Dysregulation of apoptosis and defective clearance of inflammatory cells could lead to the persistence of inflammation and excessive tissue injury.	14576987
Inflammation, Necrosis	Altered Intercellular Communication	The inflammation improved temporarily, but we operated through an outside incision because symptoms recurred and cervical skin became necrotic after one week.	14577326
Inflammation, Atherosclerosis	Altered Intercellular Communication	However, elderly patients show a greater progress in the deterioration of indices of both inflammation and atherosclerosis and therefore are not able to improve nutritional parameters.	14577506
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Serum metalloproteinase 9 levels in patients with coronary artery disease: a novel marker of inflammation.	14577520
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Therefore, the present study was aimed at verifying whether MMPs may represent sensitive markers of inflammation in patients with coronary artery disease.	14577520
Inflammation, Coronary Artery Disease, Dental Plaque	Altered Intercellular Communication	These findings suggest that measurement of serum MMP-9 levels may represent a novel marker of inflammation in patients with known coronary artery disease and might provide an index of plaque activity in this clinical setting.	14577520
Inflammation, Fibrosis Assessment, Hyperkeratosis	Altered Intercellular Communication	Tissue specimens were blindly examined by two independent pathologists for hyperkeratosis, fibrosis, cutaneous annexes, capillaries, inflammation, cellular debris, and granulating tissue.	14578249
Inflammation	Altered Intercellular Communication	Group A patients showed a predominance of inflammatory elements as well as matrix alterations, vessel disruptions, inflammation, and debris.	14578249
Inflammation, Fibrosis Assessment, Hyperkeratosis	Altered Intercellular Communication	Semiquantitative analysis confirmed the prevalence of hyperkeratosis, fibrosis, inflammation, and cellular debris in group A patients (P < 0.05), whereas cutaneous annexes, capillaries, and granulating tissue were more prevalent in group B lesions (P < 0.01).	14578249
Inflammation, Lymphoma, Neoplasms, Necrosis	Altered Intercellular Communication	Indefinite diagnoses were rendered in 33 patients (25%), including LGA versus gliosis (n = 8 patients), necrosis and/or inflammation (n = 3 patients), nondiagnostic material (n = 17 patients), suspicious for lymphoma (n = 2 patients), suspicious for GBM (n = 2 patients), and high-grade neoplasm not otherwise classified (n = 1 patient).	14579294
Inflammation, Chronic somatic dysfunction	Altered Intercellular Communication	During post-biopsy follow-up, we found low-grade systemic inflammation--measured as elevated CRP--to associate with impairment of graft function in patients with no or minimal histological findings in 6-month biopsies, and permanently low CRP to rule out chronic allograft dysfunction.	14579939
APP gene, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Abdominal aortic aneurysm (AAA) is characterized by chronic aortic wall inflammation and loss of matrix components.	14580234
Airway structure, ARCN1 gene, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Efficacy of the novel phosphodiesterase-4 inhibitor BAY 19-8004 on lung function and airway inflammation in asthma and chronic obstructive pulmonary disease (COPD).	14580925
Inflammation	Altered Intercellular Communication	Selective inhibitors of phosphodiesterase-4 (PDE4) inhibit the hydrolysis of intracellular cAMP, which may result in bronchodilation and suppression of inflammation.	14580925
Excessive tearing, Inflammation	Altered Intercellular Communication	All patients remained free of epiphora and clinical inflammation while the stents were in place, but re-obstruction of the lacrimal system occurred in all patients less than 2 months after the stents were removed.	14581012
Inflammation	Altered Intercellular Communication	Plasma inflammatory biomarkers may not adequately reflect local tissue inflammation.	14581396
Vascular Diseases, Thrombosis, Inflammation, Atherosclerosis, Dyslipidemias, Dysglycemia, Obesity, Hypertension, CTCAE	Altered Intercellular Communication	Risk factors for vascular disease include obesity, dyslipidemia, hypertension, dysglycemia, insulin resistance, inflammation, thrombosis, and subclinical atherosclerosis.	14581403
Inflammation, Exudate	Altered Intercellular Communication	Both dressings were changed approximately once a week and no differences in signs of inflammation, amount of exudate and odor, or incidence of leakage were observed.	14581709
Inflammation, Hypertensive (finding), diabetic	Altered Intercellular Communication	This study is the first report demonstrating that either EPA or DHA reduce in vivo oxidant stress without changing markers of inflammation, in treated hypertensive, type 2 diabetic subjects.	14583341
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Estimation of inflammation by Doppler ultrasound: quantitative changes after intra-articular treatment in rheumatoid arthritis.	14583566
Pain Distress Question, Inflammation, Swelling, SYNOVIAL SWELLING, Sore to touch	Altered Intercellular Communication	At baseline, disease activity was estimated clinically by target join pain on a 100 mm visual analogue scale, on which the target joint was scored 0-3 for swelling and tenderness, and by ultrasound measurements of grey scale pixels, colour Doppler pixels, and the spectral Doppler resistive index (RI) as indicators of synovial swelling and inflammation.	14583566
Alzheimers Disease", Inflammation	Altered Intercellular Communication	Alzheimer's may not be an inflammation after all.	14584508
ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	The pathophysiology of chronic obstructive pulmonary disease (COPD) features pulmonary inflammation with a predominant alveolar macrophage involvement.	14586044
Inflammation, Infection caused by Helicobacter pylori, Atrophy of mucosa of stomach	Altered Intercellular Communication	Gastric mucosal atrophy gradually improved (in addition to improvements in inflammation and neutrophil activity) with successful eradication of H. pylori infection.	14587302
Necrotizing granulomatous inflammation, Tuberculosis, Silicosis, Anthracosis	Altered Intercellular Communication	There were four kinds of lesions observed: dust reticulation (anthracosis), necrotizing granulomatous inflammation, tuberculosis and silicosis.	14587541
Inflammation, Tuberculosis	Altered Intercellular Communication	Narcotizing granulomatous inflammation of lungs that was probably tuberculosis and clear tuberculosis were found in 14 (7%) and 8 (4%) cases respectively.	14587541
Necrotizing granulomatous inflammation, Granuloma	Altered Intercellular Communication	The pathologic findings included caseous granuloma and/or positive acid-fast bacilli (AFB) in 39 cases and chronic granulomatous inflammation with negative AFB in 6 cases.	14587562
Inflammation, atherosclerotic	Altered Intercellular Communication	The results of our study reveal a possible relationship between endothelial cell injury and inflammation in atherosclerotic coronary arteries.	14587642
Inflammation, Fibrous	Altered Intercellular Communication	Inflammation and fibrous tissue formation were the main tissue reactions to the implants.	14588330
Tumor necrosis, Inflammation, Atherosclerosis	Altered Intercellular Communication	Tumor necrosis factor (TNF) is an important cytokine in the inflammation process of atherosclerosis.	14593215
Steatohepatitis, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	There was no difference in C-reactive protein levels regarding the degree of hepatic steatosis and inflammation and the stage of liver fibrosis.	14593532
Communicable Diseases, Inflammation	Altered Intercellular Communication	pneumoniae infection exerts no significant influence on the unspecific markers of inflammation.	14593953
Inflammation, polychondritis	Altered Intercellular Communication	Relapsing polychondritis is characterized by recurrent inflammation and eventual destruction of cartilaginous tissues, primarily affecting the ears, nose, respiratory tract, and eyes.	14594576
Inflammatory, Inflammation	Altered Intercellular Communication	Nevertheless, patients who require conversion to open appendectomy tend to have high CT inflammation grades of 4 or 5, which indicate the presence of periappendiceal fluid or an inflammatory mass or abscess.	14595145
Lupus Erythematosus	Altered Intercellular Communication	Inflammation parameters, ANA and lupus anticoagulant declined significantly after the treatment.	14596428
Excessive tearing, Inflammation	Altered Intercellular Communication	A 55-year-old patient presented with recurrent inflammation, discharge, and epiphora 24 months after insertion of lacrimal plugs; surgical intervention and partial resection of the cicatrized canaliculi was necessary.	14597051
Granulomatous inflammation, Sarcoidosis, SYNOVITIS, GRANULOMATOUS, WITH UVEITIS AND CRANIAL NEUROPATHIES (disorder), Uveitis, Crohn Disease	Altered Intercellular Communication	Both Blau syndrome and Crohn disease involve granulomatous inflammation and uveitis, as does sarcoidosis.	14597055
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	Autopsy studies and animal experiments suggest that microglial inflammation contributes to the pathogenesis of amyotrophic lateral sclerosis (ALS).	14597108
Inflammation, Myringitis, Acute otitis media	Altered Intercellular Communication	inflammation of the tympanic membrane with blister(s) in children <2 years and study the relationship between bullous myringitis and recurrent acute otitis media.	14597372
Inflammation, Hypertension, CTCAE, Cerebrovascular accident	Altered Intercellular Communication	These findings support a possible role of acute hypertension after stroke as an inflammatory stimulus contributing to ischemic brain inflammation.	14597640
Inflammation	Altered Intercellular Communication	Volvulus of epiploic appendix was seen in 67.6% operated patients, inflammatory changes--in 28.1% (primary inflammation was diagnosed in 4.2% patients).	14597959
Inflammation, Aortic Aneurysm	Altered Intercellular Communication	Vascular prosthetic implantation is associated with prolonged inflammation following aortic aneurysm surgery.	14598100
Inflammation	Altered Intercellular Communication	Indices of inflammation and cytokine concentrations peaked at 1-3 days after surgery and decreased thereafter; however, IL-8 increased again after day 7.	14598100
Inflammation, Peripheral Nervous System, Vasculitic neuropathy, Vasculitis, CTCAE, Vasculitis	Altered Intercellular Communication	Vasculitic neuropathy occurs as a component of systemic vasculitis or as an isolated angiitis of the peripheral nervous system, and T cell-mediated inflammation is detected in its pathogenesis.	14598179
Inflammation	Altered Intercellular Communication	Histopathology of the skin lesion showed the multifocal granulomatous inflammation containing many acid-fast bacilli associated with infiltration of foam cells and neutrophils.	14598635
Membranoproliferative Glomerulonephritis, Type II	Altered Intercellular Communication	Basic calcium phosphate (BCP) deposition disease is a crystal-induced inflammation syndrome.	14598656
Inflammation, Specimen Type - Fistula	Altered Intercellular Communication	We speculated that the fistula occurred as a result of the inflammation with the abscess formation.	14598695
Inflammation, Chest Pain	Altered Intercellular Communication	The prognostic value of markers of inflammation in patients with troponin T-negative chest pain before discharge from the emergency department.	14599630
Inflammation, Chest Pain	Altered Intercellular Communication	To assess the prognostic value of markers of inflammation for rule-out purposes in patients admitted to the emergency department with troponin T-negative chest pain.	14599630
Malignant neoplasm of liver, Necrotizing granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	All five patients (44-71 years old; two women, three men) underwent surgery, and had a preoperative diagnosis of malignant hepatic neoplasm and a postoperative histological diagnosis of chronic granulomatous inflammation, suggestive of tuberculosis.	14600128
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	The results suggest that IL-18 is involved in stroke-induced inflammation and that initial serum IL-18 levels may be predictive of stroke outcome.	14600822
Inflammation, Atheroma	Altered Intercellular Communication	Recent evidence has demonstrated that inflammation plays a major role in the initiation and progression of atheroma plaques.	14602213
Inflammation	Altered Intercellular Communication	Histologic examination of the coronary artery distal to the stent revealed chronic inflammation and an intimal acute inflammatory infiltrate, with polymorphonuclear leukocytes.	14602281
Inflammation, Aortic Diseases	Altered Intercellular Communication	Dissection is also seen in primary aortic diseases, including those that involve aortic inflammation.	14602321
Alzheimers Disease", Dementia, Vascular	Altered Intercellular Communication	Neurosteroids: Cerebrospinal fluid levels for Alzheimer's disease and vascular dementia diagnostics.	14602750
Pain Distress Question, Inflammation, Thrombophlebitis	Altered Intercellular Communication	In group 2 there was no significant difference between the two areas, but patients reported significant relief of pain and inflammation associated with postsclerotherapy thrombophlebitis.	14603191
Pain Distress Question, Inflammation	Altered Intercellular Communication	In veins 3 mm or smaller, statistical significance was not achieved, but thrombectomy resulted in faster resolution of the postsclerotherapy pain and inflammation.	14603191
Pain Distress Question, Inflammation, Varicosity, Edema, Ulcer, Skin Pigmentation	Altered Intercellular Communication	A single examiner scored the VCSS (0-3) clinically for pain, varicose veins, edema, skin pigmentation, inflammation, induration, ulcer duration and size, and compressive therapy.	14603193
Pain Distress Question, Inflammation, Edema	Altered Intercellular Communication	Of the 420 limbs screened, VCSS was 0 in 283 limbs, and VCSS was 1 or greater in the following categories: pain, 63 limbs; varicose veins, 70 limbs; edema, 51 limbs; skin pigmentation, 17 limbs; inflammation, 2 limbs; induration, 8 limbs; and compressive therapy, 9 limbs.	14603193
Inflammation, Atherosclerosis	Altered Intercellular Communication	Increasing evidence points to the inflammatory character of atherosclerosis, and several parameters of inflammation have been proposed as cardiovascular risk markers.	14603210
Inflammation, Dysplasia, Carcinoma, Ulcer	Altered Intercellular Communication	A total of 96 biopsies was performed in 81 of the 668 patients (12.1%), of which 30 (31.3%) were diagnosed histologically as carcinoma/carcinoma in situ (CIS) and the remainder as inflammation (31.3%), keratosis (26.6%), dysplasia (21.9%), ulcer (2.1%), other (3.1%), or no abnormality (1.0%).	14603451
Atherosclerosis	Altered Intercellular Communication	Atherosclerosis, as a chronic inflammatory condition, can be mediated by immunological reactions.	14604295
Intraocular inflammation	Altered Intercellular Communication	In Group B, 4 patients (50%) developed moderate intraocular inflammation and 5 patients achieved a final visual acuity of 5/10 or better.	14604722
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Studies have indicated that inflammation, in conjunction with the production of reactive oxygen species, may play a key role in lung cancer development.	14604894
ARCN1 gene, Asthma, Airway structure	Altered Intercellular Communication	In patients with asthma and COPD, breath CO levels were potentially influenced by underlying airway inflammation, suggesting misclassification in the assessment of smoking status by breath CO.	14605044
Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	Charts were reviewed for demographic, clinical, hemodynamic, oxygen transport, inflammation, and organ dysfunction data.	14605064
Inflammation, Cardiac complication	Altered Intercellular Communication	Although both glycoxidation and inflammation can contribute to severe vascular and cardiovascular complications, the role that these pathogenic mechanisms play in the complex response of the whole organism remains to be elucidated.	14605280
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Factors associated with ileal mucosal morphology and inflammation in patients with ileal pouch-anal anastomosis for ulcerative colitis.	14605565
Inflammation, Metaplasia, Ulcerative Colitis, Villous atrophy	Altered Intercellular Communication	A higher total load of fecal anaerobic bacterial flora is strongly associated with degree of colonic metaplasia, villous atrophy, and inflammation activity after surgery for ulcerative colitis.	14605565
Inflammation, Crohn Disease	Altered Intercellular Communication	Cytokine/chemokine transcript profiles reflect mucosal inflammation in Crohn's disease.	14605835
Inflammation	Altered Intercellular Communication	With regard to chronic inflammation (moderate to severe in the corpus or antrum), none of the features, alone or in combination, showed a sensitivity of more than 56 %.	14606018
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Inflammation plays a significant contributory role in the pathogenesis of chronic heart failure (CHF).	14607202
Inflammation, Thrombosis, Atherosclerosis	Altered Intercellular Communication	Furthermore, the immune modulator CD154 has been receiving increased attention, since it plays a key role in the pathophysiology of multicellular vascular events such as thrombosis, inflammation and atherosclerosis.	14607202
Inflammation, Kidney Diseases	Altered Intercellular Communication	The laboratory findings and urine analysis of this disease suggested absences of biochemical indicators of inflammation in endemic nephropathy patients (Table 2, Table 3), which is in accordance with the previous in investigations.	14608855
Inflammation, Chest Tubes, Empyema	Altered Intercellular Communication	On the priority of treatment for chronic empyema, at first, both thoracic tube drainage and thoracostomy should be performed as a first-stage operation, and if they could not be effective, after the combined inflammation was settled down, then the omental flap transposition should be considered as a two-stage operation.	14608919
Inflammation, Asthma, Chronic sinusitis	Altered Intercellular Communication	Features of airway remodeling and eosinophilic inflammation in chronic rhinosinusitis: is the histopathology similar to asthma?	14610473
Epithelial Damage, Asthma, Craniosynostosis, Chronic eosinophilic inflammation	Altered Intercellular Communication	In this study, we tested the hypothesis that histopathologic features of asthma, namely, the chronic eosinophilic inflammation, epithelial damage, and basement membrane thickening of the airway mucosa, are also present in sinonasal specimens from patients with CRS.	14610473
Inflammation, Craniosynostosis, Allergic	Altered Intercellular Communication	Strikingly heterogeneous eosinophilic inflammation, which did not differ between allergic and nonallergic patients, was detected in all patients with CRS and was absent in all healthy control subjects.	14610473
Inflammation, Asthma	Altered Intercellular Communication	The histopathologic findings of asthma, namely, heterogeneous eosinophilic inflammation and features of airway remodeling, are also present in CRS.	14610473
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide (eNO) is a noninvasive test that measures airway inflammation.	14610474
Inflammation, Asthma	Altered Intercellular Communication	These findings suggest that eNO provides information about the asthmatic state consistent with information from other markers of inflammation.	14610474
Thyroid Crisis, Chronic Obstructive Airway Disease, Respiratory Failure, Acute inflammation, Cardiac Arrhythmia	Altered Intercellular Communication	We retrospectively analyzed the outcome of 10 patients (4 males, 6 females; 70 years of age, range, 54-79, Burch-Wartofsky point scale, 61; range, 40-85) with thyrotoxic storm, thyroid autonomy, and severe cardiorespiratory and renal failure with cardiac arrhythmia, coronary artery or chronic obstructive pulmonary disease, or acute inflammation.	14611702
Inflammation, Dysplasia, Hyperplasia, Fibrosis Assessment, Goblet Cells	Altered Intercellular Communication	The main histopathologic features of the gallbladder included inflammation, mucosal atrophy/or hyperplasia, goblet cell metaplasia, mucous gland hyperplasia, Rokitansky-Aschoff sinus formation, dysplasia and fibrosis.	14611879
Inflammation, Fever	Altered Intercellular Communication	These findings suggest that fevers seen after total knee arthroplasty are at least partly the result of surgical site inflammation and subsequent local and systemic release of the endogenous pyrogen interleukin 6.	14612649
Inflammation, Arthritis	Altered Intercellular Communication	Turnover of type II collagen and aggrecan in cartilage matrix at the onset of inflammatory arthritis in humans: relationship to mediators of systemic and local inflammation.	14613270
Inflammation, Arthritis	Altered Intercellular Communication	To determine in vivo the extent of damage to, and changes in turnover of, articular cartilage type II collagen (CII) and the proteoglycan aggrecan following the onset of inflammatory arthritis in humans, and to examine the hypothesis that there are direct relationships between cartilage biomarkers of damage/turnover and clinical, histologic, and molecular markers of inflammation.	14613270
Arterial Stiffness, Inflammation, Microvascular Angina, Endothelial dysfunction	Altered Intercellular Communication	Chronic inflammation and increased arterial stiffness in patients with cardiac syndrome X. Endothelial dysfunction and subangiographic atheroma have been reported in patients with cardiac syndrome X (CSX) but little is known regarding chronic inflammation and reduced arterial distensibility as pathogenic mechanisms.	14613736
Pancreatitis, pancreatitis biliary	Altered Intercellular Communication	In biliary pancreatitis, surgery should not be considered as a primary option until the resolution of the pancreatic inflammation and its systemic effects.	14614634
Communicable Diseases, Mitochondria, Inflammation	Altered Intercellular Communication	Mitochondrial leakage produces a genetic response which mirrors that following infection, but because mitochondrial leakage is continuous the shift in gene expression is persistent, leading to the chronic inflammation characteristic of old age.	14615212
Inflammation, Fibrosis Assessment, Pathological Dilatation	Altered Intercellular Communication	The neoplastic follicles were found to be separated by thick connective tissue, and periductal chronic inflammation with periductal fibrosis and duct ectasia was found in the residual atrophic gland.	14615825
Crohn Disease, organic disease, Neoplasms, Colitis	Altered Intercellular Communication	The main organic disorders found were Crohn's disease (56%), ulcerative/indeterminate colitis (30%), bowel tumours (5%), appendicitis/diverticulitis (2%) and other inflammatory conditions (8%).	14616167
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	A promising tool in ultrasonographic evaluation of inflammation in rheumatoid arthritis.	14616209
Refractory anemias, Inflammation	Altered Intercellular Communication	RI seems to be an objective alternative to pixel estimation of the degree of inflammation and treatment response in RA.	14616209
Molecular Abnormality, Dermatitis	Altered Intercellular Communication	Photoageing shows histological features of chronic skin inflammation without clinical and molecular abnormalities.	14616376
Dermatitis	Altered Intercellular Communication	Thus photoageing displays histological features of chronic skin inflammation.	14616376
Inflammation	Altered Intercellular Communication	However, no molecular sign of inflammation was observed and we even found a decreased expression of interleukin-1beta mRNA in sun-exposed compared with sun-protected sites.	14616376
Inflammation	Altered Intercellular Communication	Furthermore, the patients' skin looked normal and did not display any clinical inflammation.	14616376
Enteritis, Intestines, Small	Altered Intercellular Communication	We do not recommend routine screening for vitamin B12 deficiency in this group of patients unless they have undergone additional small bowel resection or have ongoing small bowel inflammation.	14618349
Dermatitis, Atopic, Inflammation	Altered Intercellular Communication	Almost half of the patients with atopic dermatitis experience chronic inflammation of the eyelids, the conjunctiva and the cornea.	14618353
Inflammation, Malignant Neoplasms, Atopy	Altered Intercellular Communication	Chronic inflammation is a possible cause for the development of malignancies, especially if associated with some kind of immunological defect as in atopic patients.	14618353
Dermatitis, Atopic, Inflammation	Altered Intercellular Communication	All 7 patients had a long history of atopic dermatitis and chronic of inflammation of the conjunctiva and cornea.	14618353
Airway structure	Altered Intercellular Communication	Acetaldehyde also is found in cigarette smoke and may cause airway inflammation.	14619338
Airway structure	Altered Intercellular Communication	Our findings suggest that acetaldehyde potentially causes airway inflammation via increased GM-CSF production through nuclear translocation of NF-kappa B.	14619338
Inflammation, Hyperplasia	Altered Intercellular Communication	Biopsy of the overlying tissue associated with a left-impacted third molar revealed no significant pathologic process other than inflammation and some hyperplasia within the dental follicle.	14620643
Inflammation, Renal Colic, Abnormality of the urinary system, Stricture of ureter, Congenital Abnormality, Fibrosis Assessment, Urolithiasis, Malignant Neoplasms	Altered Intercellular Communication	CT urography detected urinary abnormalities in 57 of 59 patients with the clinical manifestation of acute renal colic, including 45 cases of urolithiasis, three urinary malignancies, one congenital abnormality, and eight ureteral strictures (due to chronic inflammation or fibrosis).	14620676
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Candesartan reduces oxidative stress and inflammation in patients with essential hypertension.	14620923
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	The present study was designed to test the hypothesis that blockade of angiotensin II type-1 receptors reduces oxidative stress and inflammation in patients with essential hypertension.	14620923
Inflammation, Hypertensive (finding), Tissue injury	Altered Intercellular Communication	This may provide useful information for determining therapeutic strategies to minimize tissue injury by inflammation and oxidative stress in hypertensive patients.	14620923
Inflammation, Panniculitis, Nodular Nonsuppurative	Altered Intercellular Communication	Weber Christian disease or idiopathic lobular panniculitis is a skin condition that features recurring inflammation in the fat layer of the skin.	14621048
Crohn Disease, Sarcoidosis, SYNOVITIS, GRANULOMATOUS, WITH UVEITIS AND CRANIAL NEUROPATHIES (disorder), Granulomatous inflammation	Altered Intercellular Communication	Sarcoidosis, Blau syndrome and Crohn's disease are complex disorders, characterised by granulomatous inflammation affecting a variety of organs.	14621080
Inflammation, Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	The macroscopic picture regarded as an inflammation of the mucous coat in patients with the IBS is not confirmed with the data of morphological research.	14621617
Dyskinetic syndrome, Parkinson Disease	Altered Intercellular Communication	The presence of neuronal elements that are indicative of dopaminergic neurotransmission in cerebellum suggest that this brain region may contribute to the motor symptoms or dyskinesia seen in Parkinson's disease.	14622169
Pain Distress Question, Inflammation	Altered Intercellular Communication	A visual analog scale (VASpain), cutaneous joint temperature and circumference were measured for subjective ongoing pain and inflammation.	14622705
Migraine Disorders, Obsessive-Compulsive Disorder, TYMS wt Allele	Altered Intercellular Communication	Neurotransmitter dysregulation, particularly involving the serotonin system, has been implicated in the pathogenesis of TS, obsessive-compulsive disorder, and migraine headache.	14623732
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation as a risk factor for atrial fibrillation.	14623805
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	The presence of systemic inflammation determined by elevations in C-reactive protein (CRP) has been associated with persistence of atrial fibrillation (AF).	14623805
Contrast bronchogram, Airway structure, hilar adenopathy, Pleural Effusion, CTCAE, Interstitial Disease	Altered Intercellular Communication	Available chest radiographs and thoracic CTs were reviewed for the presence of the following radiographic findings: airspace disease, air bronchograms, airways inflammation and peribronchial thickening, interstitial disease, pleural effusion, and hilar adenopathy.	14624321
Prostate carcinoma, prostatitis	Altered Intercellular Communication	To examine whether subclinical prostatic inflammation might influence serum prostate-specific antigen (PSA) levels in men with clinically undetectable prostate cancer.	14624908
Inflammation	Altered Intercellular Communication	The extent of inflammation tended to increase as the prostate volume increased (P = 0.006).	14624908
Inflammation, Aggressive behavior	Altered Intercellular Communication	Patients with a PSA greater than 2.5 ng/mL had a greater extent and aggressiveness of inflammation than those with PSA levels of 2.5 ng/mL or less (P = 0.004 and P = 0.050, respectively).	14624908
Inflammation, Aggressive behavior	Altered Intercellular Communication	However, no statistically significant differences were found in terms of the extent of inflammation or inflammatory aggressiveness between patients with PSA levels greater than 4.0 ng/mL and those with PSA levels of 4.0 ng/mL or less.	14624908
Prostate carcinoma, prostatitis	Altered Intercellular Communication	Our results indicate that subclinical prostatic inflammation is not the etiology of a serum PSA greater than 4.0 ng/mL in men without clinically detectable prostate cancer.	14624908
Tissue damage, Inflammation, Demyelinating Diseases, MS gene	Altered Intercellular Communication	Magnetic resonance imaging (MRI) allows examining inflammation and central nervous system (CNS) tissue damage in patients suffering from multiple sclerosis (MS), a demyelinating disease of the CNS.	14625033
Inflammation	Altered Intercellular Communication	Increased diffusivity and severe metabolic alterations were compatible with biopsy findings of necrotizing inflammation.	14625226
Inflammation, Acquired Immunodeficiency Syndrome	Altered Intercellular Communication	(1)H-MRS and diffusion-weighted imaging may both support the diagnosis of HSE in patients with AIDS and help in the follow-up of necrotizing inflammation.	14625226
Osteomyelitis, Inflammation, Infection, Osteolysis	Altered Intercellular Communication	Device-associated infections after implants or endoprostheses inflict local inflammation and ultimately osteolysis, a clinical entity referred to as posttraumatic osteomyelitis.	14625473
Typhlitis, Colitis, Hematologic Neoplasms, Leukopenia, Hyperthyroidism	Altered Intercellular Communication	Neutropenic colitis, characterized by neutropenia plus cecal and ascending colon inflammation, is a rare complication of chemotherapy in hematological malignancies and, less commonly, of medication used to treat other diseases (e.g., hyperthyroidism).	14625610
Rheumatoid Arthritis, Polycystic Ovary Syndrome	Altered Intercellular Communication	Polycystic ovarian syndrome and rheumatoid arthritis: possible physiopathogenetic clues to hormonal influences on chronic inflammation.	14625815
Rheumatoid Arthritis, Polycystic Ovary Syndrome	Altered Intercellular Communication	Polycystic ovarian syndrome and rheumatoid arthritis: possible physiopathogenetic clues to hormonal influences on chronic inflammation.	14625815
Papillomatosis, Chronic inflammation, Carcinoma, Lobular, Ductal Carcinoma, Malignant Lesion	Altered Intercellular Communication	Histopathology showed a spectrum of 10 benign and nine malignant breast lesions: five mastopathies, two fibroadenomas, two chronic inflammations, and one papillomatosis, as well as five invasive ductal carcinomas and four invasive lobular carcinomas.	14626298
Airway structure, Asthma	Altered Intercellular Communication	When questioned about the underlying cause of asthma, only 7.8% of asthmatics mentioned airway inflammation, and only 17.6% stated that inhaled corticosteroids were the most effective medication for reducing airway inflammation.	14626337
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Homocysteine in patients with rheumatoid arthritis in relation to inflammation and B-vitamin treatment.	14626626
Cholecystitis, Cholestasis, Gangrene	Altered Intercellular Communication	Gallbladder inflammation and cholestasis result and bacterial invasion of the organ ensues, culminating in AAC, frequently with gangrene.	14627341
Weight Gain	Altered Intercellular Communication	Inflammation markers predict increased weight gain in smoking quitters.	14627754
Pneumonitis	Altered Intercellular Communication	Meanwhile, the 67Ga citrate uptake index (GUI) on 67Ga lung scans was measured in order to evaluate the severity of lung inflammation in active ILD.	14627851
Pneumonitis	Altered Intercellular Communication	In addition, no correlation between the degree of damage to the pulmonary vascular endothelium and the severity of lung inflammation was found.	14627851
Pneumonitis	Altered Intercellular Communication	In conclusion, L/L ratios on 99mTc-HMPAO lung scans and GUI on 67Ga lung scans are different to the findings of chest X-rays and have the potential to objectively detect the degree of damage to the pulmonary vascular endothelium and the severity of lung inflammation in active IDL.	14627851
Inflammation	Altered Intercellular Communication	The expression of MMP-2 was relevant to the inflammation grade and stage of liver fibrosis(P < 0.01).	14628352
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide (eNO) has been used as a surrogate of airway inflammation in mild asthma.	14629652
Airway structure, Asthma	Altered Intercellular Communication	In ICS-treated asthma, eNO reflects clinical activity, PbE and AHR but not eosinophilic airway inflammation.	14629652
Pleurisy, Empyema	Altered Intercellular Communication	The results from our series indicated that false positive results for pleural fluid CEA level were most commonly observed in patients with empyema and parapneumonic effusion and the CEA level showed a significant correlation to the indices of pleural inflammation.	14629653
Pleurisy, Pleural Effusion, Malignant	Altered Intercellular Communication	The serial measurement of pleural fluid CEA level may be useful as a means of monitoring resolution of pleural inflammation and excluding the possibility of a malignant pleural effusion.	14629653
Cushing Syndrome	Altered Intercellular Communication	Ectopic hormonal production in the present case suggests pulmonary tumorlets should be considered in the differential diagnosis of Cushing's syndrome.	14629755
Degenerative polyarthritis, Inflammation, Synovitis	Altered Intercellular Communication	Synovial fluid from these patients with different grades of primary osteoarthritis of the knee joint with and without synovial inflammation (synovitis) was collected during surgical procedures.	14629959
Inflammation	Altered Intercellular Communication	Osteoarthritic patients with synovial inflammation showed significantly higher levels of CD44H and v6, but not v5, than osteoarthritic patients without synovial inflammation.	14629959
Inflammation	Altered Intercellular Communication	CD44H and CD44v6, but not CD44v5, are significantly up-regulated in osteoarthritic synovial inflammation.	14629959
Pneumonitis	Altered Intercellular Communication	Clearance of apoptotic neutrophils by alveolar macrophages plays an important role in the resolution phase of lung inflammation.	14631114
Pneumonitis, Necrosis	Altered Intercellular Communication	Furthermore, the rapidity of the transition emphasizes the importance of the prompt clearance of apoptotic neutrophils before they progress to secondary necrosis at the site of lung inflammation.	14631114
Intraocular inflammation	Altered Intercellular Communication	The therapeutic strategy and the progression of intraocular inflammation are reported.	14631276
Communicable Diseases, Inflammation	Altered Intercellular Communication	For all patients, infection and inflammation were finally controlled.	14631276
Gastrointestinal inflammation, Osteoporosis	Altered Intercellular Communication	Osteoporosis is associated with enhanced bone resorption, that seems be linked to excessive intestinal inflammation.	14631305
Inflammation, Helicobacter pylori	Altered Intercellular Communication	Morphologic characteristics, presence of Helicobacter pylori (H. pylori), and markers of differentiation, inflammation, and proliferation were evaluated by histochemical and immunohistochemical techniques.	14631367
Inflammation, Fibrosis Assessment, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	A positive correlation of ACS with grading of inflammation was found (r=0.52, P<0.03) but not with fibrosis staging.	14631465
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In contrast, plasma MDA correlates with fibrosis staging (r=0.51, P<0.03) and with PIIIP (r=0.57, P<0.03) but without grading of inflammation.	14631465
Inflammation, Acute otitis media, Ear Inflammation	Altered Intercellular Communication	At acute otitis media or otitis media with effusion, the tympanic cavity becomes inflamed, accompanied by inflammation of the eustachian tube mucosa and a stenotic tendency.	14631769
Inflammation, Ear Inflammation	Altered Intercellular Communication	Healing from otitis media is accompanied by decreased eustachian tube mucosa inflammation.	14631769
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We surmise that, depending on how inflammation disappears, fibrosis of the eustachian tube mucosa occurs, leading to a pathologically patulous eustachian tube.	14631769
Inflammation, Ear Inflammation	Altered Intercellular Communication	Many aspects of the causation of this condition remain unclear, but we surmised that in patients with earlier otitis media, a pathological patulous eustachian tube develops during resolution of inflammation.	14631769
Osteomyelitis, Pressure Ulcer, Inflammation	Altered Intercellular Communication	The histologic findings were classified in 4 types of pathomorphologic changes: type 1, decubitus ulcer confined to soft tissue, no inflammation (n = 7); type 2, decubitus ulcer involving bone, no inflammation (n = 7); type 3, decubitus ulcer involving bone, inflammation of soft tissue, no osteomyelitis (n = 1); and type 4, decubitus ulcer involving bone, presence of osteomyelitis (n = 13).	14632571
Osteomyelitis, Inflammation	Altered Intercellular Communication	In all cases with osteomyelitis, inflammation was exclusively confined to the superficial parts of the os sacrum.	14632571
Granulomatosis, Orofacial, Granulomatous inflammation	Altered Intercellular Communication	Orofacial granulomatosis (OFG) comprises of a group of conditions, all characterized histologically by the presence of granulomatous inflammation.	14632932
Inflammation	Altered Intercellular Communication	Alcohol abuse may involve an altered neuroendocrine response that mediates lymphocyte-derived proopiomelanocortin (POMC) production and inflammation.	14634483
Inflammation	Altered Intercellular Communication	Lipopolysaccharide-stimulated interleukin (IL)-1 receptor antagonist (IL-1 Ra) as a marker for chronic inflammation was determined.	14634483
Hypoglycemia	Altered Intercellular Communication	Hormonal counterregulation and consecutive glimepiride serum concentrations during severe hypoglycaemia associated with glimepiride therapy.	14634699
Inflammation	Altered Intercellular Communication	In patients with CAD plasma levels of CRP are associated with an impaired endothelial function suggesting a correlation between inflammation and the integrity of the endothelium.	14635381
Asthmatic Airway Remodeling	Altered Intercellular Communication	The findings support previous indications that one important component in asthmatic airway inflammation, the cysteinyl-leukotriene pathway remains relatively unopposed by oral glucocorticoids.	14635978
Inflammation	Altered Intercellular Communication	Understanding the trafficking cues that mediate CNS leucocyte infiltration might promote the development of flexible and selective means to modulate inflammation to achieve clinical benefit.	14636165
Coughing, Inflammation, Fever, CTCAE	Altered Intercellular Communication	After temporary improvement of skin symptoms under peroral glucocorticoid treatment, a hemorrhagic-purulent discharge started from the nose, he began to have fever, malaise, cough, and a chest X-ray revealed inflammation in the lung.	14636209
Intraocular inflammation	Altered Intercellular Communication	Interleukin-8 (IL-8) is believed to be involved in the progression of intraocular inflammation.	14636843
Intraocular inflammation, Endophthalmitis, CTCAE	Altered Intercellular Communication	IL-8 is thus considered to play a role in the progression of intraocular inflammation, and granulocytes are thought to be a possible source of IL-8 in endophthalmitis.	14636843
Intraocular inflammation	Altered Intercellular Communication	In the evaluation of a patient with intraocular inflammation in whom PIOL is suspected, CDR3 polymorphism analysis is recommended to confirm clonality.	14638722
Inflammation, Carcinogenesis	Altered Intercellular Communication	Inflammation and gonadotropins are hypothesized to influence ovarian carcinogenesis.	14639616
Diabetes Mellitus, Metabolic Syndrome X, Cardiovascular Diseases	Altered Intercellular Communication	Even in the absence of late-stage consequences such as diabetes and cardiovascular disease, subtle derangements in sex hormones are present in the metabolic syndrome, and may contribute to its pathogenesis.	14641004
Inflammation, Communicable Diseases, Anemia, Malignant Neoplasms, idarubicin, Chronic disease	Altered Intercellular Communication	The distinction between iron deficiency anaemia (IDA) and the anaemia that accompanies infection, inflammation or malignancy, commonly termed the anaemia of chronic disease (ACD), is often difficult, as the conventional laboratory indices of iron status are often influenced by acute phase responses.	14641138
Intraocular inflammation	Altered Intercellular Communication	Long-term efficacy of mycophenolate mofetil in the control of severe intraocular inflammation.	14641155
Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation remained under control in 10 patients, unchanged in three and deteriorated in one patient.	14641155
Liver carcinoma, Hepatitis C, Hepatitis, Chronic, FAM126A gene	Altered Intercellular Communication	Hepatocellular carcinoma (HCC) usually develops following chronic liver inflammation caused by hepatitis C or B virus.	14642619
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a key role in all stages of atherosclerosis and in the genesis of acute coronary syndromes.	14642684
Inflammation, Periodontitis, Atherosclerosis	Altered Intercellular Communication	This study compared plasma levels of established risk markers for atherosclerosis and indices of inflammation in 50 patients with severe periodontitis to those in 46 healthy cases.	14643270
Inflammation	Altered Intercellular Communication	We contemplate that it may had changed the immunological state that facilitated this rare inflammation.	14643484
Inflammation, Edema, Uveitis	Altered Intercellular Communication	Inflammation and macular edema might be contributing factors in macular hole formation in patients with uveitis.	14644235
Inflammation, Edema	Altered Intercellular Communication	This case indicates that treatment of inflammation and macular edema might lead to macular hole closure in similar cases.	14644235
Airway structure, Asthma	Altered Intercellular Communication	Natural porcine surfactant augments airway inflammation after allergen challenge in patients with asthma.	14644929
Asthma, allergic inflammation	Altered Intercellular Communication	There is increasing evidence for a role of pulmonary surfactant in asthma and allergic inflammation.	14644929
Asthma, allergic inflammation	Altered Intercellular Communication	In murine asthma models, recent studies have demonstrated that surfactant components downregulate the allergic inflammation.	14644929
Asthma	Altered Intercellular Communication	Therefore, we tested the hypothesis that in individuals with mild asthma, a natural porcine surfactant preparation (Curosurf) given before segmental allergen challenge can reduce the allergic airway inflammation.	14644929
Airway structure	Altered Intercellular Communication	More recently, exhaled nitric oxide (FE(NO)) measurements and induced sputum analysis to assess airway inflammation have been highlighted.	14644933
Barrett Esophagus, Inflammation, Adenocarcinoma Of Esophagus	Altered Intercellular Communication	Biopsy samples and resected materials were identified from patients with SSBO (10), IMNSCJ (14), a normal SCJ with (14) and without (12) inflammation, conventional Barrett's oesophagus (BO) (12), and oesophageal adenocarcinoma (12).	14645692
immunopathology specialty, Traumatic, Congenital Abnormality	Altered Intercellular Communication	First, there is an etiologic distribution in ten groups: age-related, hormonal, pharmacologic, immunopathic, hyponutritional, dysgenetic, inflammatory, traumatic, neurodeprivative, and tantalic.	14648364
Inflammation, Abdominal Pain	Altered Intercellular Communication	Abdominal pain resolved and endoscopical signs of inflammation improved.	14648378
Gastrointestinal inflammation	Altered Intercellular Communication	Segmental biopsy specimens are essential for the differential diagnosis of intestinal inflammation.	14648411
Inflammation, Traumatic injury	Altered Intercellular Communication	Lesions due to injury have a worse prognosis than those caused by direct continuous or repeated pressure, inflammation or where no aetiological factor exists.	14648949
Sialadenitis, Swelling	Altered Intercellular Communication	Sialoadenitis is a non-inflammatory condition that affects mainly the parotid, and is characterised by bilateral, painless swelling, which is an appreciable problem in young women.	14649690
Inflammation, Infection, Bladder Neoplasm	Altered Intercellular Communication	The presenting clinical signs are completely nonspecific and usually related to predisposing factors (infections, inflammation, bladder tumour).	14650292
Inflammation	Altered Intercellular Communication	PE is a disease associated with inflammation and vascular endothelial dysfunction.	14652656
Inflammation, Eclampsia, Pre-Eclampsia	Altered Intercellular Communication	We therefore hypothesised that women with a history of PE or GH might have abnormal levels of markers of endothelial activation or inflammation, reflecting either an innate predisposition to preeclampsia or changes induced by the eclamptic process.	14652656
Granuloma, Psoriasis, Folliculitis, neutrophilic, Panniculitis, Granulomatous inflammation, Pyoderma Gangrenosum, Vasculitis, CTCAE	Altered Intercellular Communication	There were 8 cases of neutrophilic dominant dermal infiltrates, including pyoderma gangrenosum, 6 cases of granuloma annulare/necrobiosis lipoidica-like lesions, 5 cases of sterile neutrophilic folliculitis, 5 cases of panniculitis, 4 cases of vasculitis, 2 cases of psoriasis, 2 cases of lichenoid and granulomatous inflammation, and 1 case of classic metastatic CD.	14652821
Gingival Hyperplasia, Chronic inflammation	Altered Intercellular Communication	Multiple biopsies performed at various time periods were histologically reported to be gingival hyperplasia with chronic inflammation.	14653398
Inflammation, Osteolysis	Altered Intercellular Communication	We believe that circulating cytokines cannot be regarded as markers of osteolysis, a condition characterised by a local inflammation without systemic signs of inflammation.	14653608
Communicable Diseases, Endophthalmitis, CTCAE, Inflammation	Altered Intercellular Communication	Endophthalmitis is a severe condition caused by inflammation of the ocular cavity that often is associated with infection of the internal structures of the eye.	14654765
Autoimmune Diseases, Diabetes Mellitus, Insulin-Dependent, Autoimmune Polyglandular Syndrome	Altered Intercellular Communication	In patients with type 1 diabetes, especially in combination with associated organ-specific autoimmune diseases, autoimmune polyglandular syndrome should be considered and adequately treated with those hormones that are reduced.	14655075
Inflammation, Malnutrition, Hypoalbuminemia	Altered Intercellular Communication	Loss of muscle mass and hypoalbuminemia each may result in part from either malnutrition, inflammation, or a combination of both.	14655192
Inflammation, Edema	Altered Intercellular Communication	Inflammatory cells, possibly activated by lipids, release phospholipase A(2) and platelet-activating factor, enhancing edema formation, inflammation, and surfactant alterations.	14656749
Inflammation, Tissue injury	Altered Intercellular Communication	Polymorphisms in cytokine genes can influence immune responses, inflammation, and tissue injury and may affect the outcome of hematopoietic stem-cell transplantation.	14657427
Inflammation, Ischemic stroke	Altered Intercellular Communication	Inflammation, homocysteine, and vitamin B6 status after ischemic stroke.	14657454
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	We investigated B6 status, tHcy, and inflammation (measured by C-reactive protein [CRP]) in patients with stroke and controls.	14657454
Inflammation, Visual Acuity	Altered Intercellular Communication	At the age 32 retrobulbar inflammation of the second cranial nerve appeared with visual acuity weakness.	14658055
Infarction, Inflammation	Altered Intercellular Communication	At autopsy, there were multiple small infarctions in the cerebral cortex and dark areas in the meninges, suggesting localized inflammation.	14658399
Inflammation	Altered Intercellular Communication	An open brain biopsy showed multiple vessels containing granulomatous inflammation with giant cells.	14658405
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Involvement of inflammation in acute coronary syndromes assessed by levels of high-sensitivity C-reactive protein, matrix metalloproteinase-9 and soluble vascular-cell adhesion molecule-1.	14658408
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is important in the development of atherosclerosis.	14658408
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	This study investigated whether inflammation is related to the onset of acute coronary syndrome.	14658408
Inflammation, Acute Coronary Syndrome, Dental Plaque	Altered Intercellular Communication	These results suggest that plaque destabilized by MMP-9 produced in response to inflammation participates in the mechanism of acute coronary syndrome.	14658408
Inflammation	Altered Intercellular Communication	Substantial loss of endothelium and fibroblasts, reduced collagen bundles crimping, inflammation (81%) and disappearance of layered structure (59%) was identified.	14658816
Fibrinous, Serous, Inflammation	Altered Intercellular Communication	Histopathological examination revealed serous, fibrinous and haemorrhagic inflammation in most pulmonary alveoli, with capillary engorgement and some capillary microthrombosis.	14660106
Inflammation, Rheumatic mitral stenosis	Altered Intercellular Communication	The presence of systemic inflammation and its impact on the procedural success of percutaneous balloon mitral valve commissurotomy (PBMC) in patients with rheumatic mitral stenosis has not been previously demonstrated.	14661006
Inflammation, Mitral Valve Stenosis	Altered Intercellular Communication	Systemic inflammation is common in patients with rheumatic mitral valve stenosis, and the relationship between procedural success and CRP suggests persistent inflammation may affect the results of PBMC.	14661006
Inflammation, Specimen Type - Fistula, Rupture	Altered Intercellular Communication	The pleural wall surrounding the fistula was hypertrophic in parts, suggesting possible repetitive inflammation related with the rupture.	14661552
Neurodegenerative Disorders, Inflammation, Data types - Address, "Alzheimers Disease	Altered Intercellular Communication	Inflammation seems to play a role in progressive neurological degenerative diseases such as Alzheimer's disease (AD).	14661818
Inflammation, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	We examined whether sustained alleviation of inflammation as monitored by serum alanine aminotransferase (ALT) levels was associated with longer survival in hepatectomized hepatocellular carcinoma (HCC) patients with hepatitis C virus-associated liver cirrhosis (HCV-LC).	14662024
Inflammation, Myocardial Infarction, Coronary Artery Disease	Altered Intercellular Communication	N-terminal pro-brain natriuretic peptide in relation to inflammation, myocardial necrosis, and the effect of an invasive strategy in unstable coronary artery disease.	14662251
Inflammation, Electrocardiogram: myocardial infarction (finding), Myocardial, Coronary Artery Disease	Altered Intercellular Communication	Biochemical indicators of cardiac performance (e.g., NT-proBNP), inflammation (e.g., IL-6), and myocardial damage (e.g., cTnT) predict mortality in unstable coronary artery disease (UCAD) (i.e., unstable angina or non-ST-segment elevation myocardial infarction [MI]).	14662251
Inflammation, Coronary heart disease	Altered Intercellular Communication	Plasma lipoprotein Lp(a), markers of haemostasis and inflammation, and risk and severity of coronary heart disease.	14663298
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	There was no appreciable association between Lp(a) and apolipoproteins, markers of haemostasis, fibrinolysis and inflammation and the severity of CHD.	14663298
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Furthermore, there is no good evidence that the presumed link between Lp(a) and CHD is mediated by increased levels of markers of inflammation, or interference with markers of fibrinolysis or coagulation.	14663298
Hypertriglyceridemia	Altered Intercellular Communication	Food with a high content of fat, as well as alcoholic or hormonal influences, can lead to excessive hypertriglyceridemia.	14663605
Ischemia, Inflammation, Endotoxemia, Postoperative cognitive dysfunction	Altered Intercellular Communication	Endotoxaemia, caused by splanchnic ischaemia during surgery, is believed to trigger systemic inflammation and cause postoperative organ dysfunction.	14665564
Inflammation, Hypertension, CTCAE, Inflammatory disorder	Altered Intercellular Communication	Although it has been hypothesized that hypertension is in part an inflammatory disorder, clinical data linking inflammation with incident hypertension are scarce.	14665655
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	To examine whether C-reactive protein levels, a marker of systemic inflammation, are associated with incident hypertension.	14665655
Necrotizing granulomatous inflammation, Malignant Neoplasms	Altered Intercellular Communication	Histological examination showed no malignancy and only chronic granulomatous inflammation of the ureter.	14665851
Inflammation, Gastritis	Altered Intercellular Communication	In chronic antral gastritis there was a positive relationship between the SOD activity and both the severity and activity of inflammation.	14666643
Deficiency of butyryl-CoA dehydrogenase, dissection of coronary artery, Bothered by Vomiting	Altered Intercellular Communication	The authors discuss several factors that may have contributed to the spontaneous coronary artery dissection (SCAD) including chemotherapy-induced vasospasm, hemodynamic stress of vomiting, and hormonal changes associated with pelvic radiation.	14666962
Tumor necrosis, Rheumatoid Arthritis	Altered Intercellular Communication	Upregulation of tumor necrosis factor-alpha (TNF-alpha) has been implicated in the pathogenesis of several inflammatory conditions, including rheumatoid arthritis.	14667206
Inflammation, Acute Coronary Syndrome, Dental Plaque	Altered Intercellular Communication	Inflammation is the most important mechanism of plaque disruption playing an essential role in acute coronary syndromes.	14668096
Inflammation, Thrombosis	Altered Intercellular Communication	Stimulation of interleukins increases adhesion molecules, fibrinogen and plasminogen activator inhibitors,which cause the activation of inflammation and thrombosis.	14668096
Inflammation, Chronic heart failure, Kidney Failure	Altered Intercellular Communication	Patients with acute or chronic inflammation, renal failure or chronic heart failure were excluded from the study.	14668096
Cataract, Intraocular inflammation	Altered Intercellular Communication	Early objective assessment of intraocular inflammation after phacoemulsification cataract surgery.	14670423
Intraocular inflammation, Uveitis	Altered Intercellular Communication	While observations in human and animal models suggest an association between certain prostaglandin-like agents and intraocular inflammation, this report is one of the first to suggest a link between bimatoprost and intraocular inflammatory reaction.	14670442
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	It is controversial whether mutations in cystic fibrosis transmembrane conductance regulator intrinsically dysregulate inflammation.	14670800
Chronicity, Inflammation, Mucous Membrane	Altered Intercellular Communication	Histologically, spirochetosis was identified in all parts of the colon and was not strongly associated with active inflammation, mucosal injury, or changes of chronicity.	14671970
Inflammation, Postoperative Hemorrhage	Altered Intercellular Communication	Precaution must be taken for postoperative arterial hemorrhage caused by delayed inflammation.	14672016
Inflammation, Specimen Type - Fistula, Diverticulosis, Diverticulitis, Abscess with diverticular disease of colon	Altered Intercellular Communication	The abnormal findings on the CT scan were as follows: diverticular abscess (16%), diverticulitis (37%), diverticulosis without inflammation (15%), free air (10%) and fistula (1%).	14672782
Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Inflammation-sensitive plasma proteins and incidence of myocardial infarction in men with low cardiovascular risk.	14672880
Refractory anemias, Disease, Cardiovascular Diseases	Altered Intercellular Communication	Young to middle aged patients with RA with low disease activity, free from cardiovascular risk factors and overt cardiovascular disease, have an altered endothelial reactivity that seems to be primarily related to the disease associated chronic inflammatory condition.	14672888
Nephritis	Altered Intercellular Communication	Finally, DMSA renal SPECT is the best and the most sensitive examination for detecting the extension area of renal inflammation and correlated with the renal outcome.	14674222
Inflammation	Altered Intercellular Communication	Dithranol-induced inflammation is maximal at 48-72 h, suggesting that daily application of dithranol may not be optimal.	14674905
Kidney Failure, Chronic, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	The prevalence of cardiovascular disease (CVD) and inflammation is high in patients with end-stage renal disease (ESRD).	14675060
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Furthermore, low levels of adiponectin are associated with inflammation in ESRD.	14675060
Inflammation	Altered Intercellular Communication	The measurements were analyzed by pairwise correlation with each other as well as with standard parameters of inflammation [C-reactive protein (CRP), joint leukocyte count].	14675085
Inflammation	Altered Intercellular Communication	In the plasma, the link between inflammation (CRP increase) and TF activation is weak, and a non-TF-mediated mechanism of coagulation activation could explain these findings.	14675085
Refractory anemias, Inflammation, Arthropathy	Altered Intercellular Communication	Although fibrinolytic activity is linked to inflammation, the increased amounts of TAFI in the joint, particularly in RA, may explain why fibrin formation is so prominent in this condition compared with other joint diseases.	14675085
Inflammation, Fibrosis Assessment, Hepatitis C	Altered Intercellular Communication	Collectively, hepatic fibrosis and inflammation appear to play key roles in the increase in insulin resistance in patients with chronic HCV infection.	14675263
Inflammation, Helicobacter-associated gastritis, Stomach Carcinoma, Gastritis	Altered Intercellular Communication	The severe inflammation, increased cell proliferation and marked acid inhibition observed in subjects with Helicobacter pylori-associated enlarged-fold gastritis suggest that enlarged-fold gastritis may be a risk factor for gastric carcinoma.	14675267
Intermittent asthma, allergic inflammation, Atopy	Altered Intercellular Communication	Thus, in atopic children sensitized to HDM with mild intermittent asthma, IgE levels in blood appear to reflect systemic (blood eosinophils) and organ-specific (FeNO) markers of allergic inflammation but not pulmonary volumes or the degree of airflow limitation.	14675476
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Elevated serum tumour-associated trypsin inhibitor (TATI) levels have been observed in association with malignancy or inflammation.	14675563
Inflammation, Refractory anemias, Degenerative polyarthritis, Rheumatoid Arthritis, Arthritis, Psoriatic	Altered Intercellular Communication	The objectives of this study were to evaluate the [3H]PK11195 binding parameters in a model of acute inflammation, the N-formylmethionine-leucine-phenylalanine (fMLP)-stimulated neutrophil cell membranes, and to analyze if alterations of peripheral-type benzodiazepine receptor (PBR) characteristics occurred in neutrophil cell membranes of patients affected by osteoarthritis (OA), rheumatoid arthritis (RA), and psoriasic arthritis (PA).	14675564
Depressive disorder, Depressed mood	Altered Intercellular Communication	These results, directly obtained from the brain of depressed patients, reinforce the involvement of noradrenergic neurotransmission in depressive illness.	14675811
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Inflammation and fibrosis around lower and upper follicles were rated.	14676070
Inflammation	Altered Intercellular Communication	In the chronic stage, decreased terminal and increased miniaturized hairs were found, with variable inflammation.	14676070
Inflammation	Altered Intercellular Communication	During recovery, increasing numbers of terminal anagen hairs from regrowth of miniaturized hairs and a lack of inflammation were noted.	14676070
Abnormal thrombosis, Moyamoya Disease, Inflammation	Altered Intercellular Communication	Although abnormal thrombogenesis, inflammation and autoimmune process might be involved in the etiology, the genetic pathogenesis of Moyamoya disease is still unknown.	14676447
Virus Diseases	Altered Intercellular Communication	The pathogenesis of IPT is unknown, but it has been interpreted as an aberrant reactive condition of the nodal connective framework, possibly related to viral infections or chronic inflammatory conditions.	14677031
Herpes Zoster Ophthalmicus, Paranasal Sinus Disorder, Myositis, CTCAE 5.0, Sinusitis, Orbital Pseudotumor	Altered Intercellular Communication	Ocular disease occurs in 50%-60% adult patients with WG and may be an extension of the sinus inflammation or an orbital pseudotumour independent of the sinus disease (15%-50%); sometimes it presents as an ocular myositis.	14677032
Inflammation, Hypergammaglobulinemia, Hypoalbuminemia	Altered Intercellular Communication	Indicators of inflammation were remarkable: she had extremely high levels of serum interleukin-6 (IL-6) (398 pg/ml) in addition to hypergammaglobulinemia and hypoalbuminemia.	14677035
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Abnormal levels of serum dehydroepiandrosterone, estrone, and estradiol in men with rheumatoid arthritis: high correlation between serum estradiol and current degree of inflammation.	14677174
Refractory anemias	Altered Intercellular Communication	Accordingly, BMI could be of interest as a sensitive and inflammation-independent predictor for radiological outcome of RA.	14677176
Hip Joint, Inflammation, Joint structure of shoulder region, Synovitis	Altered Intercellular Communication	Inclusion criteria were that subjects have at least one peripheral joint with synovitis or signs of inflammation in sacroiliac, glenohumeral, or hip joints on the first visit.	14677193
Intracranial Extension, Inflammation, Cervicofacial actinomycosis, Dental caries	Altered Intercellular Communication	Poor dental hygiene leading to caries and an inflammation in his right upper jaw probably was the cause of cervicofacial actinomycosis with intracranial extension.	14677482
Inflammation, Destruction of tissue	Altered Intercellular Communication	It is still unclear whether the antibodies to 44 and 53 kD proteins play a role in the pathogenesis of MD or if they instead represent the result of inflammation and tissue destruction.	14678278
Inflammation, Carcinoma	Altered Intercellular Communication	Middle-aged men with carcinoma could be missed during the acute phase of inflammation.	14678376
Parkinson Disease, Schizophrenia	Altered Intercellular Communication	Dopamine (DA) neurons degenerate in Parkinson's disease and dopamine neurotransmission may be affected in psychotic states seen in schizophrenia.	14678778
Inflammation, Thrombosis, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Tissue factor expression induced by local inflammation is involved in the pathogenesis of thrombosis in patients with nonvalvular atrial fibrillation.	14678810
Inflammation, Thrombosis, Ischemic stroke	Altered Intercellular Communication	Candidate gene polymorphisms related to inflammation, thrombosis and lipid metabolism have been implicated in the development of ischemic stroke.	14681304
Hyperlipidemia, Inflammation, Thromboembolic stroke, Diabetes Mellitus, Hypertension, CTCAE	Altered Intercellular Communication	After adjustment for multiple comparisons and age, smoking, body mass index, hypertension, hyperlipidemia and diabetes, two related to inflammation [a val640leu polymorphism in the P-selectin gene (OR=1.63, 95% CI 1.22-2.17, P=0.001) and a C582T polymorphism in the interleukin-4 gene (OR=1.40, 95% CI 1.13-1.73, P=0.003)] were found to be independent predictors of thrombo-embolic stroke.	14681304
Aneurysm, Blood Clot, Inflammation	Altered Intercellular Communication	The aneurysm wall covered with thrombus is thinner and shows more frequent signs of inflammation, apoptosis of SMCs, and degraded extracellular matrix.	14681629
Inflammation, Aneurysm	Altered Intercellular Communication	It is not clear whether the bacteria contribute to weakening of the aortic wall by eliciting inflammation or whether they are secondary colonizers of aneurysms.	14681645
Inflammation, Ureter Compression	Altered Intercellular Communication	With resolution of the retroperitoneal inflammation, long-term follow-up revealed spontaneous release of both ureteral and caval compression.	14681651
PHB2 gene, Inflammation, gastrointestinal, Arthritis, Reactive	Altered Intercellular Communication	Reactive arthritis (ReA) is a sterile inflammation of the synovial membrane of one or more joints developing after urogenital or gastro-intestinal infection.	14682205
allergic inflammation	Altered Intercellular Communication	Leukotrienes (LTC4, LTD4, LTE4) belong to eicosanoids and they play important role in allergic inflammation.	14682223
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterised by chronic inflammation of the respiratory tract.	14682411
Airway structure, ARCN1 gene	Altered Intercellular Communication	The increased IL-6 levels in exhaled breath condensate may reflect airway inflammation in patients with COPD.	14682411
Intestinal metaplasia, Inflammation, Gastritis, Atrophic	Altered Intercellular Communication	Gastritis was assessed according to the Sydney classification system for activity, inflammation, atrophy, intestinal metaplasia, and H pylori density.	14684569
Inflammation	Altered Intercellular Communication	In the OM triple group, H pylori was eradicated in 90 (88%) patients, and activity and inflammation decreased substantially in both the antrum and corpus (p<0.001, baseline v two years).	14684569
Communicable Diseases, Inflammation, Atrophic	Altered Intercellular Communication	In the 83 OM only patients with continuing infection, there was no change in antral and corpus gastritis activity or atrophy, but inflammation increased (p<0.01).	14684569
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Eradication of H pylori eliminates gastric mucosal inflammation and induces regression of corpus glandular atrophy.	14684569
Crohn Disease, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Crohn's disease (CD) is characterised by inflammation, muscle layer overgrowth, and collagenous fibrosis of the intestinal tract, with no effective therapy against collagen accumulation.	14684581
Syringomyelia, Androgen-Insensitivity Syndrome, Arnold-Chiari Malformation, Type I	Altered Intercellular Communication	Growth hormone insensitivity syndrome associated with syringomyelia and type I Chiari malformation.	14686753
Inflammation, Endothelial dysfunction, Diabetes Mellitus	Altered Intercellular Communication	Endothelial dysfunction, oxidative stress and systemic inflammation play an important role in the enhanced cardiovascular risk in diabetes.	14686966
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	A single pathologist (ST) scored all biopsies (inflammation 0-6; fibrosis 0-4).	14687145
Inflammation, Pain Distress Question, Erythema, Swelling, Arthritis, Gouty	Altered Intercellular Communication	Clinically, gouty arthritis is associated with severe inflammation, such as pain, swelling and erythema of the joints.	14687896
Arthritis, Gouty, Inflammation	Altered Intercellular Communication	We examined the levels of MMP-2 and -9 in 40 synovial fluids (SFs) from the knee joints of 24 patients with gouty arthritis and compared them with the clinical and laboratory variables of inflammation.	14687896
Arthritis, Gouty	Altered Intercellular Communication	The analysis of MMP-9 in SF samples can reveal the inflammatory condition of the knee joints with gouty arthritis.	14687896
Granulomatous inflammation, Non-Small Cell Lung Carcinoma, Silicosis, Sinus histiocytosis	Altered Intercellular Communication	Histologic findings in patients with non-small cell lung cancer and false-positive results of mediastinal positron emission tomography included granulomatous inflammation, sinus histiocytosis, and silicosis.	14688703
Granulomatous disorder, Sarcoidosis, Choroiditis	Altered Intercellular Communication	There are granulomatous diseases such as sarcoidosis where some areas of choroidal inflammation that cannot be detected with other methods are shown by ICG.	14689324
Neurogenic Inflammation	Altered Intercellular Communication	[Prevalence and drug tolerance of mycoplasma in patients with urogenital inflammation].	14689895
Neurogenic Inflammation	Altered Intercellular Communication	To observe the prevalence and drug tolerance of mycoplasma(Ureaplasma urealyticum and Mycoplasma hominis) in patients with urogenital inflammation.	14689895
Neurogenic Inflammation, prostatitis, Pelvic Inflammatory Disease	Altered Intercellular Communication	Three thousand and fifty-five patients with urogenital inflammation such as non-gonococcal urethritis(NGU), chronic prostatitis or pelvic inflammation from 1999 to 2003 were included.	14689895
Granuloma, Inflammation, Leprosy, Necrosis	Altered Intercellular Communication	Additional histologic findings included birefringent foreign material in 14 biopsies (50%), focal necrosis (43%), elastophagocytosis (39%), linear peri-neural granulomas resembling leprosy (25%), increased dermal mucin (18%) and lichenoid inflammation (14%) [two with plasma cells resembling syphilis (7%)].	14690461
Inflammation, Graft-vs-Host Disease	Altered Intercellular Communication	In interpreting skin biopsies, it is important to recognize that brisk inflammation may be seen in GVHD in the setting of solid organ transplantation, in contrast to the more sparse inflammation typical of GVHD following BMT.	14690464
HD Term Type, Inflammation	Altered Intercellular Communication	Inflammation is frequently elevated, and seems to be episodic in hemodialysis (HD) patients.	14691348
HD Term Type, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	This study explores inflammation forms, characteristics and causes which are probably related to the high cardiovascular disease (CVD) morbidity in HD patients.	14691348
Inflammation	Altered Intercellular Communication	Inflammation due to common clinical events is added, periodically, to this microinflammation.	14691348
Inflammation	Altered Intercellular Communication	The high level persistent microinflammation as well as the superimposed--due to clinical events--inflammation could be related to the CVD in these patients.	14691348
Inflammation	Altered Intercellular Communication	The suggested therapeutic lifestyle approach may contribute to the reduction of the prevalence of the MS, beyond the levels of several lipid, inflammation, and coagulation markers.	14691427
Inflammation, Restenosis	Altered Intercellular Communication	Perivascular inflammation plays a key role in the development of restenosis after percutaneous transluminal angioplasty (PTA).	14691583
Inflammation, Blood Clot, Calcinosis, Atherosclerosis	Altered Intercellular Communication	Study slides were stained with hematoxylin and eosin and Verhoeff-van Gieson and evaluated for thrombus, collagen, elastin, atherosclerosis, hemosiderin, calcification, and inflammation.	14691915
Inflammation, Calcinosis, Atherosclerosis	Altered Intercellular Communication	Intima was thickened in all patients and consisted of collagen (100%), elastin (67%), hemosiderin (56%), inflammation (53%), atherosclerosis (32%), and calcification (15%).	14691915
Small cell carcinoma of lung, Inflammation	Altered Intercellular Communication	Its level increases during inflammation and in small cell lung cancer.	14692663
Inflammation	Altered Intercellular Communication	The concentrations of sTNFRs in TMJ synovial fluid are higher in the presence of painful ADDwoR/OA, which could modulate intracapsular inflammation.	14693207
Pain Distress Question, Inflammation	Altered Intercellular Communication	Rofecoxib is a selective cyclooxygenase-2 inhibitor that reduces pain and inflammation without inhibiting platelet function.	14693607
Pain Distress Question, Hemorrhage, Inflammation	Altered Intercellular Communication	Rofecoxib belongs to class of analgesics known as cyclooxygenase-2 inhibitors that reduce pain and inflammation with less risk of bleeding than standard nonsteroidal antiinflammatory drugs.	14693607
Inflammation, Atherosclerosis	Altered Intercellular Communication	Interaction of atherosclerosis and inflammation in elderly subjects with poor cognitive function.	14694032
Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Systemic lupus erythematosus (SLE), a complex multigenic disease, is a typical antibody-mediated autoimmune disease characterized by production of autoantibodies against a variety of autoantigens and immune complex-type tissue inflammation, most prominently in the kidney.	14695357
Inflammation, Fracture	Altered Intercellular Communication	TPS implants showed a higher incidence of inflammation and recession, while IMZ implants had a higher incidence of implant fracture after functional loading.	14696659
Inflammation	Altered Intercellular Communication	One of the many associated risk factors is chronic inflammation.	14696756
Inflammation	Altered Intercellular Communication	The relationship of baseline markers of chronic inflammation with the presence of CVD was assessed in a large cohort of stable dialysis patients.	14696756
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Levels of the chronic inflammation marker sialic acid correlate strongly with CRP and are increased in patients with cardiovascular disease, but show no relationship to hemodialysis session.	14696756
Inflammation	Altered Intercellular Communication	Thus sialic acid may be a superior marker to CRP for assessment of chronic inflammation in patients undergoing dialysis.	14696756
Inflammation	Altered Intercellular Communication	Increased coronary arterial release of interleukin-1 receptor antagonist and soluble CD40 ligand indicative of inflammation associated with culprit coronary plaques.	14697457
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	We sought to determine whether inflammation is manifested by increased concentrations of selected markers in ostial blood sampled from a culprit coronary artery proximal to an atherosclerotic plaque.	14697457
Inflammation	Altered Intercellular Communication	The increased concentration of IL-1 receptor antagonist and sCD40L in blood drawn from the culprit coronary artery compared with that taken from the peripheral artery suggests that these cytokines contribute directly to inflammation in response to coronary intervention and may potentiate a systemic inflammatory state.	14697457
Pain Distress Question, Swelling, Inflammation	Altered Intercellular Communication	Local complications were reported in 12% of patients: local swelling (6/57), complain of local pain at site (3/57) and local inflammation (2/57).	14698495
Inflammation, Failure (biologic function)	Altered Intercellular Communication	This includes inadequate drainage of the head of gland, failure to drain small ducts, and perineural inflammation.	14700288
Inflammation	Altered Intercellular Communication	For the 1 VG, genes involved represent inflammation and wound healing; for the 1 VP, involved genes demonstrate a tempered wound repair response and increased epithelial manifestations.	14700388
Epiglottitis, Inflammation	Altered Intercellular Communication	Epiglottitis is supraglottic inflammation of the oropharynx caused by infective, thermal, or caustic insult.	14700569
Chorioretinitis, Communicable Diseases, Inflammation	Altered Intercellular Communication	The appearance of toxoplasmic retinochoroiditis lesions varies with duration of active retinal infection and intensity of inflammation.	14700638
Inflammation, Communicable Diseases, Unknown (origin) (qualifier value), Congenital absence of lung, Experimental Organism Basal Cell Carcinoma, Herpes, Traumatic injury, Facial paralysis, Lacrimal Duct Obstruction	Altered Intercellular Communication	The causes of lacrimal obstruction were idiopathic and trauma, congenital agenesis, infection, inflammation, herpes, basal cell carcinoma, radiation therapy, penicillin-induced Steven-Johnsons syndrome, systemic chemotherapy, and facial nerve palsy.	14700651
Chlamydia Infections	Altered Intercellular Communication	Chlamydial infection causes chronic inflammation of the conjunctiva.	14701961
Inflammation, Chlamydia Infections, Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	It is worthy of further study to determine whether chronic inflammation resulting from chlamydial infection increases the risk of MALT lymphoma or it is coincidental.	14701961
Inflammation, Atherosclerosis	Altered Intercellular Communication	The observed diet-gene interactions further suggest that dietary n-6 polyunsaturated fatty acids promote, whereas marine n-3 fatty acids inhibit, leukotriene-mediated inflammation that leads to atherosclerosis in this subpopulation.	14702425
Inflammation, Renal pain, Fever, CTCAE, Pyuria	Altered Intercellular Communication	Its usual signs and symptoms comprise renal pain, fever, inflammation, and pyuria.	14702820
Pain Distress Question, Inflammation	Altered Intercellular Communication	Adverse reactions were restricted to local symptoms such as pain and inflammation at injection sites which were fully reversible.	14703062
Inflammation	Altered Intercellular Communication	The main functional roles of these genes are cell communication, apoptosis and inflammation.	14704720
Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	Thus, suppression of inflammation in the cadaveric donor might be a cheap and promising intervention for postischemic acute renal failure.	14704720
Inflammation	Altered Intercellular Communication	Clinical or serologic signs of inflammation were exclusion criteria.	14704840
Bronchitis	Altered Intercellular Communication	TK can induce marked bronchial inflammation in animal models and TK activity is increased in the airway secretions of symptomatic asthmatics.	14705767
Airway structure, Inflammation	Altered Intercellular Communication	The observation of increased TK activity in patients with neutrophilic airway inflammation suggests that TK may play a role in modulating inflammation in ventilator-associated tracheobronchitis and may be worthy of further study to determine its source and significance.	14705767
Inflammation, Coronary heart disease	Altered Intercellular Communication	C-reactive protein (CRP), a marker of subclinical inflammation, predicts the occurrence of coronary heart disease in healthy subjects.	14706052
Inflammation, Immune System Diseases	Altered Intercellular Communication	It is shown that prostatilen has a corrective effect on hemocoagulation and immunity disorders, restores microcirculation, suppresses inflammation in the kidney and prostate.	14708243
Neurogenic Inflammation, prostatitis	Altered Intercellular Communication	Thus, prostatilen is a pathogenetically sound drug for treatment in urogenital inflammation while in chronic prostatitis it can be used as a basic therapy.	14708243
Inflammation	Altered Intercellular Communication	Wall inflammation is an important factor in the development of this complication.	14708505
Hypothalamic Dysfunction Syndromes, Obesity	Altered Intercellular Communication	In contrast, hypothalamic dysfunction as well as hormone deficiencies might play roles in obesity in these patients.	14709849
Communicable Diseases, Inflammation, Prostate carcinoma	Altered Intercellular Communication	The association of infection or inflammation of the prostate with prostate cancer has been suggested but not established.	14712152
Inflammation, Communicable Diseases, Prostate, Prostate carcinoma, prostatitis	Altered Intercellular Communication	As a result of the limitations of current methods of assessing chronic prostatitis, biochemical or tissue markers of infection or inflammation of the prostate may help clarify their role in the pathogenesis of prostate cancer.	14712152
Inflammation, Postoperative infection, Swelling, Testicular Hydrocele	Altered Intercellular Communication	The most common complications following scrotal surgery for hydroceles and spermatoceles are persistent scrotal swelling, inflammation and postoperative infection.	14713801
Inflammation, Necrosis	Altered Intercellular Communication	The remarkable atrophic change of the right lobe was thought to be due to an obstruction of the right portal veins by the spread of inflammation around the bile duct necrosis, in addition to the narrowing of the hepatic artery.	14714235
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Neither lobular inflammation nor fibrosis was observed in the surrounding liver.	14714953
Inflammation, Helicobacter pylori, Metaplasia, Atrophic, Polyposis, Gastric	Altered Intercellular Communication	The histological examination established the gastric polyp type and the presence of inflammation, activity (infiltration with polymorphonuclears), atrophy, metaplasia, and Helicobacter pylori in the surrounding mucosa.	14716418
Inflammation, Hyperplastic Polyp, Atrophic, Adenomatous Polyps	Altered Intercellular Communication	The mucosa surrounding hyperplastic polyps was characterized by the statistically significant presence of inflammation (100%, p=0.0001) and activity (84.3%, p=0.001) while the mucosa surrounding the adenomatous polyps showed statistically significant presence of inflammation (100%, p=0.0001) activity (81.8%, p=0.001), atrophy (72.7%, p=0.017) and metaplasia (72.7%, p=0.017).	14716418
Inflammation, Hyperplastic Polyp, Atrophic, Adenomatous Polyps	Altered Intercellular Communication	Hyperplastic polyps are associated with the presence of inflammation and activity in the surrounding mucosa, whereas adenomatous polyps are associated with the presence of inflammation, activity, atrophy, and metaplasia in the surrounding mucosa.	14716418
Inflammation, Claudication (finding)	Altered Intercellular Communication	Chronic transcutaneous electrical stimulation of calf muscles improves functional capacity without inducing systemic inflammation in claudicants.	14718904
Inflammation	Altered Intercellular Communication	IA patients with severe inflammation had highest levels of NO, while those with mild inflammation had normal levels of NO.	14719189
Neoplasms, Intracranial, Intraocular inflammation, Lymphocyte count decreased	Altered Intercellular Communication	The patient developed manifestations of intraocular inflammation secondary to the intracranial neoplasm (masquerade syndrome) and lymphocytopenia--with a low CD4 cell count--representing an immunodeficiency state which etiology was undiagnosed.	14719316
Necrotizing granulomatous inflammation, Actinomycosis	Altered Intercellular Communication	Pathological diagnosis was chronic granulomatous inflammation with actinomycosis.	14719453
Pelvic Pain, Neurogenic Inflammation, Neuralgia	Altered Intercellular Communication	Some of the pelvic pain syndromes seem to have features of neurogenic inflammation and neuropathic pain in common.	14719719
Inflammation	Altered Intercellular Communication	The changes in the nasal mucosa and the parotid gland showed chronic inflammation with Mikulicz cells.	14720140
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Severity and extent of osteoarthritis and low grade systemic inflammation as assessed by high sensitivity C reactive protein.	14722211
Inflammation, Osteopenia	Altered Intercellular Communication	This is in keeping with accumulating evidence that systemic inflammation is associated with bone resorption and bone loss.	14722347
Inflammation, Severe (severity modifier)	Altered Intercellular Communication	The observer missed one major lesion (columnar-lined esophagus) because of suspected inflammation and described 10 non-existing major lesions (sensitivity 98%: 95% CI[89%, 99%], specificity 80%: 95% CI[66%, 90%]).	14722545
Inflammation, Dry Eye Syndromes, Keratoconjunctivitis Sicca	Altered Intercellular Communication	Keratoconjunctivitis sicca, or dry eye syndrome, is a complex condition characterized by inflammation of the ocular surface and tear-producing glands.	14723107
Inflammation, Dry Eye Syndromes	Altered Intercellular Communication	Inflammation: a unifying theory for the origin of dry eye syndrome.	14723109
Inflammation, septic	Altered Intercellular Communication	There were no significant differences between the synbiotic and control groups in bacterial translocation (12.1% v 10.7%; p = 0.808, chi(2)), gastric colonisation (41% v 44%; p = 0.719), systemic inflammation, or septic complications (32% v 31%; p = 0.882).	14724157
Inflammation, Atherosclerosis	Altered Intercellular Communication	The role of inflammation in the development of atherosclerosis and its complications has been recently documented.	14724693
Inflammation, Fibrosis Assessment, Hepatitis C	Altered Intercellular Communication	In the 250 hepatitis C virus patients (fibrosis stage 0 to 4), viral genotype and portal, but not lobular, inflammation were univariate predictors of HOMA-IR.	14724822
Inflammation, Brain Infarction, Ischemic stroke, Cerebrovascular accident	Altered Intercellular Communication	Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome.	14725719
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Plasma IL-6, and other markers of peripheral inflammation, were measured at pre-determined timepoints in the first week after stroke onset.	14725719
Electrocardiogram: myocardial infarction (finding), Cerebrovascular accident	Altered Intercellular Communication	Risk of myocardial infarction and stroke in smokers is related to plasma levels of inflammation-sensitive proteins.	14726408
Airway structure, Inflammation, Asthma	Altered Intercellular Communication	The pattern of glucocorticoid-sensitive inflammation during an asthma exacerbation is more reminiscent of an antiviral response than an eosinophil-predominant response to allergen and implies an independent role for airway T cells in mediating asthma flares and in determining glucocorticoid efficacy in the treatment of this disease.	14726420
Undifferentiated carcinoma, Pharyngitis, Tuberculosis	Altered Intercellular Communication	Nasopharyngeal granulomatous inflammation and tuberculosis complicating undifferentiated carcinoma.	14726921
Undifferentiated carcinoma, Pharyngitis, Tuberculosis	Altered Intercellular Communication	Four cases of nasopharyngeal granulomatous inflammation after radiotherapy for undifferentiated carcinoma were analyzed for tuberculosis, and the histologic features were compared.	14726921
Inflammation, Tuberculosis	Altered Intercellular Communication	Diligent search for organisms in postirradiation granulomatous inflammation is warranted to avoid missing an occult tuberculosis infection.	14726921
Cessation of life, Inflammation, Sudden infant death syndrome	Altered Intercellular Communication	The cases were divided into three groups: group 1 typical SIDS ( n=47), group 2 SIDS with signs of mild inflammation of the respiratory tract ( n=50) and group 3 unnatural death controls ( n=23).	14727122
Inflammation, Sudden infant death syndrome	Altered Intercellular Communication	This demonstrates that the Reid index has no significance in the vast majority of SIDS cases and that acute inflammation commonly does not produce an elevated Reid index.	14727122
Pituitary Adenoma	Altered Intercellular Communication	Operation was performed, and pathological examination revealed inflammation of pituitary adenoma.	14727537
Tumor necrosis, Inflammation	Altered Intercellular Communication	To test the hypothesis that physical exercise induces an antiinflammatory response that is associated with reduced chronic activation of the tumor necrosis factor (TNF)-alpha system in frail elders and that the increase in muscle strength after resistance training is limited by systemic low-grade inflammation.	14728633
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	The mechanism of chronic lung inflammation leading to lung fibrosis is unknown and does not have a characteristic inflammatory macrophage phenotype.	14729510
Pneumonitis	Altered Intercellular Communication	This study was undertaken to determine whether a change in macrophage phenotype could account for chronic lung inflammation.	14729510
Inflammation, Postoperative Complications	Altered Intercellular Communication	The main concerns about IOL implantation were poor predictability of power changes, postoperative complications, inflammation, and technical difficulty of surgery.	14730292
Inflammation	Altered Intercellular Communication	As the mucosa under traditional denture has been shown to possess reduced innervation and the histological aspect of chronic overloading, these results may be considered indicative of a tentative induction to nerve re-growth in the under-innervated epithelium, or as a response to chronic inflammation.	14731179
Inflammation	Altered Intercellular Communication	To examine the relationship between eotaxin levels in the sputum and eosinophilic inflammation.	14732790
Stomatitis, Deposition, Ulcerative Colitis	Altered Intercellular Communication	Mesangial IgA deposits could be an "occasional" further occurrence, considering the chronic inflammation of colonic mucosa and the altered immune response of patients with UC.	14732918
Inflammation, Epithelial cyst	Altered Intercellular Communication	The histopathological findings confirm the diagnosis of an epidermoid cyst, characterized by the presence of: (1) a cyst cavity lined by stratified squamous epithelium with keratinization on the surface; and (2) connective tissue with a mild inflammation.	14733477
Endocarditis	Altered Intercellular Communication	Bacterial inflammation endocarditis initially induced metaplasia of the endothelial cells which then lose contact with each other.	14735028
Inflammation	Altered Intercellular Communication	Acquired thymic cysts are multilocular and show florid xanthomatous and myofibroblastic inflammation.	14736277
Inflammation, Coronary Artery Disease, Aortic sclerosis	Altered Intercellular Communication	Adverse outcome in aortic sclerosis is associated with coronary artery disease and inflammation.	14736432
Inflammation, Coronary Artery Disease, Aortic sclerosis, Heart valve disease	Altered Intercellular Communication	The increased incidence of adverse cardiovascular events in patients with aortic sclerosis is associated with coronary artery disease and inflammation, not a result of the effects of valvular heart disease per se.	14736432
Gastritis	Altered Intercellular Communication	The immune system may contribute especially to chronic gastric mucosa inflammation.	14737951
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Moderate antrum mucosa inflammation was found in 41.2% of the examined.	14737951
Inflammation	Altered Intercellular Communication	The highest percentage of children (58.8%) presented marked inflammation.	14737951
Inflammation	Altered Intercellular Communication	No mild inflammation was found in children examined.	14737951
Gastric mucosa, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Helicobacter pylori infection in children is associated with a chronic inflammatory process of gastric and duodenal mucosa, which may have a various clinical course ranging from asymptomatic and chronic inflammatory condition to gastric ulceration.	14737951
Migraine Disorders, Depression, CTCAE	Altered Intercellular Communication	VEP abnormalities in migraine can be related to a cortical spreading depression and a central neurotransmitter alterations.	14737964
Communicable Diseases, Inflammation, Traumatic injury, Atherosclerosis	Altered Intercellular Communication	The aorta may be prone to infection, especially when its intima is structurally altered by pathologic processes like atherosclerosis, inflammation or trauma.	14738083
Communicable Diseases, Guillain-Barre Syndrome, Inflammation, Paralysed	Altered Intercellular Communication	Although subacute ascending paralysis without sensory involvement is typically evocative of Guillain-Barre syndrome, it can alternatively be due to infection or inflammation of the spinal cord.	14738952
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We can conclude that serum PAPP-A levels sensitively reflect the changes in renal function, depend on dialysis modality, and may represent a novel marker associated with inflammation and oxidative stress in chronic renal failure patients.	14739577
Intraocular inflammation, Uveitis	Altered Intercellular Communication	Based on this experience the authors are of the opinion that DT PPV is indicated in patients with uveitis for giving more precision to the diagnosis of intraocular inflammation or a masking syndrome.	14740382
Autoimmune Diseases	Altered Intercellular Communication	Sex hormones appear to play an important role as modulators of autoimmune disease onset/perpetuation.	14740444
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Therapeutical modulation of these determinants of PMN lifespan may provide a new concept for the control of inflammation in ACS.	14742636
Optic Neuritis	Altered Intercellular Communication	Inflammation of the optic nerve, optic neuritis, is rare.	14743235
Inflammation, Fibrosis Assessment, diabetic, Breast Carcinoma, Diabetic mastopathy	Altered Intercellular Communication	Diabetic mastopathy is a rare condition that occurs in type I diabetic patients and that may mimic a breast cancer due to its intense fibrosis and inflammation.	14743693
Traumatic arthropathy, Hematoma, Subdural	Altered Intercellular Communication	Inflammation markers and risk factors for recurrence in 35 patients with a posttraumatic chronic subdural hematoma: a prospective study.	14743908
Hematoma, Subdural, Inflammation, Traumatic, SDSL gene	Altered Intercellular Communication	To evaluate the role of local inflammation in the pathogenesis and postoperative recurrence of chronic subdural hematoma (CSDH), the authors conducted an investigation in a selected group of patients who could clearly recall a traumatic event and who did not have other risk factors for CSDH.	14743908
Inflammation, SDSL gene	Altered Intercellular Communication	The authors also investigated the possible relationship between high levels of local inflammation that were measured and recurrence of the CSDH.	14743908
Amyotrophic Lateral Sclerosis	Altered Intercellular Communication	This might be due to cortical overactivity of excitatory neurotransmitter glutamate observed in ALS.	14744570
Inflammation, Malnutrition	Altered Intercellular Communication	Association between cholesterol level and mortality in dialysis patients: role of inflammation and malnutrition.	14747502
Inflammation, Malnutrition	Altered Intercellular Communication	This paradox may be explained by systemic inflammation and/or malnutrition, which are associated with lower cholesterol levels and higher mortality.	14747502
Rh Factors	Altered Intercellular Communication	For CVD mortality, an inverse trend was not statistically significant in the presence of inflammation/malnutrition, and a positive association was evident in the absence of inflammation/malnutrition (RH, 1.41; 95% CI, 1.04-1.89).	14747502
Idiopathic Inflammatory Myopathies, Myositis	Altered Intercellular Communication	The idiopathic inflammatory myopathies are characterized by chronic muscle inflammation and involvement of internal organs, which contribute considerably to the morbidity and mortality of the disease.	14747766
Inflammation, Tuberculosis	Altered Intercellular Communication	All the benign lesions were inflammatory in nature, which included abscess in 6 (60%), tuberculosis in 3 (30%) and chronic non-specific inflammation in 1 (10%) case.	14747778
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	After multivariate regression analysis, histology grading 3 and 4 inflammation activity (P=0.01) and staging 3 and 4 fibrosis (P=0.01) remained independently associated with elevated GGT level.	14748879
Inflammatory, Hemorrhagic gastritis	Altered Intercellular Communication	Our data suggest that the analysis of MMP-9 indicates the inflammatory condition of the joints and that additional synovectomy may be beneficial for patients with inflammatory synovitis, compared with non-inflammatory and hemorrhagic arthritis.	14749977
Necrotizing granulomatous inflammation	Altered Intercellular Communication	A biopsy of the involved muscles revealed chronic granulomatous inflammation with several acid-fast bacilli on a Ziehl-Neelsen stain.	14749989
Inflammation, Chronic Kidney Insufficiency, Endothelial dysfunction, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation, endothelial dysfunction, and platelet activation in patients with chronic kidney disease: the chronic renal impairment in Birmingham (CRIB) study.	14750089
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Studies in the general population suggest that low-grade inflammation, endothelial dysfunction, and platelet activation are associated with an increased risk of cardiovascular events.	14750089
Inflammation, Cardiovascular Diseases, Coronary Artery Disease, Endothelial dysfunction, Chronic Kidney Diseases	Altered Intercellular Communication	Markers of inflammation, endothelial dysfunction, and platelet activation were measured in 334 patients with chronic kidney disease (serum creatinine >1.47 mg/dL [>130 micromol/L] at screening) and compared with 2 age- and sex-matched control groups, 1 comprising 92 patients with coronary artery disease and the other comprising 96 apparently healthy individuals with no history of cardiovascular or kidney disease.	14750089
Inflammation, Chronic Kidney Insufficiency	Altered Intercellular Communication	There was evidence of low-grade inflammation in the chronic renal impairment group compared with healthy controls, with higher concentrations of C-reactive protein (3.70 versus 2.18 mg/L, P < 0.01) and fibrinogen (3.48 versus 2.67 g/L, P < 0.001) and lower serum albumin concentration (41.8 versus 44.0 g/dL [418 versus 440 g/L], P < 0.001).	14750089
Renal Insufficiency, Inflammation, Endothelial dysfunction, Chronic Kidney Diseases	Altered Intercellular Communication	This cross-sectional analysis demonstrates that chronic kidney disease is associated with low-grade inflammation, endothelial dysfunction, and platelet activation, even among patients with moderate renal impairment.	14750089
Syphilitic, Inflammation	Altered Intercellular Communication	Postoperative inflammation was not more severe in our patients with syphilitic IK compared to patients undergoing PKP for other reasons.	14750229
vascular inflammations	Altered Intercellular Communication	Endovascular brachytherapy did not diminish early vascular inflammation in response to PTA or stent implantation and even induced a trend toward an increased inflammatory response.	14752194
Cerebral Amyloid Angiopathy, Inflammation, Deposition	Altered Intercellular Communication	To explore the clinical effects of inflammation associated with vascular deposits of the amyloid beta peptide (A beta), we analyzed 42 consecutive patients with pathologically diagnosed cerebral amyloid angiopathy (CAA) for evidence of an inflammatory response.	14755729
Inflammation	Altered Intercellular Communication	Inflammation with giant-cell reaction surrounding amyloid-laden vessels was identified in 7 of the 42 cases.	14755729
Inflammation	Altered Intercellular Communication	The syndrome of CAA-related perivascular inflammation appears to represent a subset of CAA with clinically distinct symptoms that may respond to immunosuppressive treatment.	14755729
Inflammation, physiopathological	Altered Intercellular Communication	These data add to evidence that inflammation against A beta can cause vascular dysfunction, a potential mechanism for the toxic response recently observed in clinical trials of A beta immunization.	14755729
Necrotizing granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	The diagnosis of tuberculosis is easily made when the classical features of pulmonary necrotizing granulomatous inflammation are seen.	14755756
Granulomatous inflammation, Coin lesion of lung, Tuberculosis	Altered Intercellular Communication	A search for acid-fast organisms leading to the correct diagnosis of tuberculosis was prompted by clinical investigations that revealed pulmonary lesions, or by repeat aspiration biopsy, which showed granulomatous inflammation.	14755756
Inflammation, External auditory canal structure	Altered Intercellular Communication	External auditory canal cholesteatoma (EACC) is a chronic inflammation of the external auditory canal and is composed of hyperproliferative epithelium.	14757970
Inflammation	Altered Intercellular Communication	The diagnostic impact of this finding is, however, limited by the fact that chronic inflammation may also be accompanied by a focal loss of CD34+ fibrocytes.	14758552
Inflammation	Altered Intercellular Communication	A half-dose regimen, although having a reduced delivery cost, inhibits plasmin and fibrinolysis without substantially effecting kallikrein-mediated inflammation associated with bypass surgery.	14759451
vascular inflammations, Peripheral arterial occlusive disease	Altered Intercellular Communication	Plasma adrenomedullin concentration is increased in patients with peripheral arterial occlusive disease associated with vascular inflammation.	14759562
vascular inflammations	Altered Intercellular Communication	Our findings indicate that the plasma AM concentration was elevated in patients with PAOD in proportion to the severity of the disease and associated with vascular inflammation.	14759562
Acute Coronary Syndrome, Inflammation	Altered Intercellular Communication	In acute coronary syndromes, the inflammation and the coagulation systems are activated, implying an impaired outcome.	14760324
Acute Coronary Syndrome, Observation Method - Coagulation, Inflammation	Altered Intercellular Communication	In non-ST-elevation acute coronary syndrome, there was a simultaneous activation of the inflammation, coagulation, and fibrinolysis systems, despite aspirin and dalteparin treatment.	14760324
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Inflammation may play a role in the pathogenesis of colorectal cancer; however, epidemiological evidence supporting this hypothesis in average-risk persons is sparse.	14762037
Malignant tumor of colon, Inflammation	Altered Intercellular Communication	These data support the hypothesis that inflammation is a risk factor for the development of colon cancer in average-risk individuals.	14762037
Inflammation, Lesion of eyelid	Altered Intercellular Communication	A chalazion, localized lipogranulomatous inflammation of the eyelid, may simulate various eyelid lesions.	14762403
Meibomian Cyst, Premalignant Lesion, Chronic inflammation	Altered Intercellular Communication	Premalignant lesions, which masqueraded as chalazion, were chronic inflammation with cellular atypia and mitotic figures (two cases, 0.2%).	14762403
Inflammation	Altered Intercellular Communication	Of the various benign conditions that were misdiagnosed as chalazion, different types of chronic inflammation (24 cases, 2.2%) were the most frequent.	14762403
Inflammation, Lesion of brain	Altered Intercellular Communication	In cases without brain lesions, activation of vascular endothelial cells and perivascular cells was related to the degree of systemic inflammation.	14762673
Inflammation, Lesion of brain	Altered Intercellular Communication	In cases with brain lesions, these cells are often activated even in the absence of systemic inflammation.	14762673
Inflammation	Altered Intercellular Communication	Under such circumstances, low-grade inflammation in the pre-existing brain lesions might enhance inflammatory signaling to the brain parenchyma from the periphery.	14762673
Delirium	Altered Intercellular Communication	The results of this study could explain the vulnerability of neurological patients to delirium caused by systemic inflammatory conditions.	14762673
Inflammation	Altered Intercellular Communication	Under such circumstances, low-grade inflammation in the pre-existing brain lesions might enhance inflammatory signaling to the brain parenchyma from the periphery.	14762673
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Both grade of inflammation and fibrosis stage improved by 3 to 5 years posttreatment compared with baseline histology (p < 0.05).	14762857
Fibrosis Assessment, Hepatic inflammation, Hepatitis C	Altered Intercellular Communication	In conclusion, loss of HCV after treatment of recurrent chronic hepatitis C with interferon and ribavirin is durable, and the durability of the SVR is associated with improvement in hepatic inflammation and regression of fibrosis.	14762857
Inflammation, Elastosis perforans serpiginosa	Altered Intercellular Communication	Involvement of inflammation is indispensable as a cause of EPS.	14763057
Inflammation, Ascites	Altered Intercellular Communication	Examination of the ascites suggested the involvement of inflammation and the coagulation-fibrinolysis system.	14763057
Elastosis perforans serpiginosa	Altered Intercellular Communication	Inflammation of a deteriorated peritoneum causes EPS, resulting in encapsulation subsequent to an accumulation of inflammatory products such as fibrin.	14763057
Inflammation, Irritation	Altered Intercellular Communication	Even without deterioration of the peritoneum, chronic inflammation and continual irritation caused EPS-like findings with encapsulation.	14763057
Inflammation, icodextrin	Altered Intercellular Communication	Peritoneal effluent markers of inflammation in patients treated with icodextrin-based and glucose-based dialysis solutions.	14763059
palladium, Inflammation, Peritonitis	Altered Intercellular Communication	The occurrence of culture-negative peritonitis in some PD patients treated with icodextrin focused our interest on subclinical inflammation in icodextrin-treated patients without peritonitis.	14763059
Endothelial dysfunction	Altered Intercellular Communication	Malnutrition-inflammation syndrome is associated with endothelial dysfunction in peritoneal dialysis patients.	14763071
palladium	Altered Intercellular Communication	In this study, we investigated the role played by malnutrition-inflammation syndrome on endothelial function markers in PD patients.	14763071
palladium, Endothelial dysfunction	Altered Intercellular Communication	In conclusion, malnutrition-inflammation syndrome may contribute to endothelial dysfunction and, consequently, to prothrombotic and proatherogenic processes in PD patients.	14763071
palladium, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	The serum HTG concentration in PD patients with diabetes is lower than that in patients without diabetes, and it is not related to examined factors of inflammation, nutrition, or adequacy of dialysis.	14763072
Inflammation	Altered Intercellular Communication	Neither total magnitude of inflammation nor specific inflammatory cell types correlated with surgical outcome in this group.	14763245
Chronic inflammation	Altered Intercellular Communication	Accumulation of 8-hydroxy-deoxyguanosine (8-OHdG), which may result from the continuous generation of reactive oxygen species associated with chronic inflammation, has been reported in human preneoplastic lesions and in cancerous tissues.	14763512
Tubular Epithelial Cell Count, Kidney Diseases	Altered Intercellular Communication	To examine the expression and localization of osteopontin (OPN), a secreted phosphoprotein implicated in the development of tubulointerstitial inflammation in various models of renal disease, in human diabetic kidneys, and to study the regulation of OPN expression in primary cultures of human renal proximal tubular epithelial cells (RPTEC).	14764057
Inflammation	Altered Intercellular Communication	We were unable to detect any cytopathologically appreciable inflammatory response at the tip of the epidural catheter which could have suggested the occurrence of inflammation in the epidural tissues.	14765048
Necrotizing granulomatous inflammation, Adenocarcinoma of prostate	Altered Intercellular Communication	A rare case of intravascular granulomatous inflammation mimicking intravascular prostatic adenocarcinoma is reported.	14765279
Adenocarcinoma, Vascular Invasion Assessment	Altered Intercellular Communication	A radical prostatectomy revealed intravascular subendothelial granulomatous inflammation mimicking vascular invasion of a high-grade adenocarcinoma found elsewhere in the prostate.	14765279
Necrotizing granulomatous inflammation, Orbital Pseudotumor	Altered Intercellular Communication	Idiopathic granulomatous inflammation is regarded as a histopathologic variant of an orbital pseudotumor and has a similar clinical presentation and treatment.	14765756
Dacryoadenitis	Altered Intercellular Communication	We present a 77-year-old man with a biopsy-proven lacrimal gland granulomatous inflammation of an unknown origin.	14765756
Kidney Failure, Interstitial inflammation	Altered Intercellular Communication	Monocyte adhesion molecule expression in interstitial inflammation in patients with renal failure.	14767017
Kidney Failure, Interstitial inflammation	Altered Intercellular Communication	We therefore studied the recruitment of monocytes and their expression of adhesion molecules CD11b and CD62L at the site of interstitial inflammation in patients with renal failure.	14767017
Interstitial inflammation	Altered Intercellular Communication	Furthermore, we studied if the capacity of monocytes to up-regulate CD11b in interstitial inflammation was determined by the interstitial concentration of chemotactic factors.	14767017
Interstitial inflammation	Altered Intercellular Communication	Three intensities of interstitial inflammation (0, intermediate and intense) were established in skin blister chambers.	14767017
Interstitial inflammation	Altered Intercellular Communication	At the site of interstitial inflammation patients had a higher expression of CD62L (intermediate, P<0.05; intense, P<0.005).	14767017
Interstitial inflammation	Altered Intercellular Communication	Furthermore, monocytes from patients had an impaired capacity to mobilize CD11b both in the peripheral circulation (P<0.005) and at the intermediate and intense sites of interstitial inflammation (P<0.005 and P<0.001, respectively) compared with cells collected from healthy subjects.	14767017
Inflammation, Kidney Failure, Exudate	Altered Intercellular Communication	The interstitial concentration of MCP-1 at the site of intermediate inflammation was significantly lower in patients with renal failure compared with the corresponding blister exudate collected from healthy subjects (P<0.05), but no differences were observed at the site of intense inflammation.	14767017
Inflammation, Inflammatory cell infiltrate	Altered Intercellular Communication	Histologically there are fundamental differences between the 2 subtypes, classic IC presenting a severe abnormality of the urothelium and characteristic inflammatory cell infiltrates while inflammation is scant in nonulcer IC.	14767289
Inflammation, Asthma	Altered Intercellular Communication	Both inflammation and remodeling influence nitric oxide output in children with refractory asthma.	14767438
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide can be used to monitor airway inflammation in asthma.	14767438
Inflammation	Altered Intercellular Communication	We hypothesized that the strong link between nitric oxide and inflammation may obscure a weaker link with airway remodeling.	14767438
Inflammation, Asthma	Altered Intercellular Communication	These findings suggest that both subacute inflammation and remodeling influence nitric oxide output in refractory asthma.	14767438
Inflammation, Primary malignant neoplasm, Weight decreased	Altered Intercellular Communication	Systemic inflammation and resting energy metabolism predicted weight loss in progressive cancer (p<0.0001).	14767534
Inflammation, Syringoma, Neoplasms	Altered Intercellular Communication	This tumor is seldom recognized and is frequently confused with benign syringoma or inflammation.	14767643
Cholangiocarcinoma, Primary malignant neoplasm, Inflammation, Fibrosis Assessment, Schistosomiasis	Altered Intercellular Communication	Glisson's fibrosis around the cancer lesion suggested that schistosomiasis japonica and cholangiocarcinoma can occur together with severe chronic inflammation of the portal vein.	14767737
ARCN1 gene, Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Pulmonary emphysema, a major component of COPD, is pathologically characterized by destructive alterations in pulmonary architectures as a result of persistent inflammation.	14769747
Communicable Diseases, Inflammation, Pneumonia	Altered Intercellular Communication	During follow-up, pneumonia was identified due to Mycoplasma pneumoniae infection that could also be confirmed as causal for the brain inflammation.	14770285
Inflammation	Altered Intercellular Communication	In 37 cases with urethral biopsy from structural zone, we described a high recurrence rate (62.5%) with "local active inflammation".	14870528
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease.	14871421
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The prevalence of increased oxidative stress and acute-phase inflammation in patients with chronic kidney disease (CKD) has not been thoroughly investigated.	14871421
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Biomarkers of oxidative stress and acute-phase inflammation were measured in a cohort of 60 patients with stage 3-5 CKD compared to a healthy subject cohort.	14871421
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	There is evidence of increased oxidative stress and acute-phase inflammation in patients with stage 3-5 chronic kidney disease compared to healthy subjects that does not closely correlate with estimates of GFR.	14871421
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation and oxidative stress may contribute to cardiovascular risk in CKD patients.	14871421
Inflammation, Acidosis, Chronic Kidney Diseases	Altered Intercellular Communication	Prevalence of acidosis and inflammation and their association with low serum albumin in chronic kidney disease.	14871424
Inflammation, Nerve injury	Altered Intercellular Communication	Inflammation associated with nerve injury produces a number of pathogenic chemical mediators of which prostanoids are a potent component.	14871450
methyldopa, Inflammation	Altered Intercellular Communication	Our results suggest that elevated CRP level is an independent risk factor for AMD and may implicate the role of inflammation in the pathogenesis of AMD.	14871913
Neurodegenerative Disorders, Mental disorders, deficiency aspects	Altered Intercellular Communication	Previously described associations between low testosterone levels and frontal lobe dysfunction in normal aged men, together with these results, suggest that the hormonal deficiency may act as a "second hit" to impair cognitive function in neurodegenerative disease.	14872022
Inflammation	Altered Intercellular Communication	Pathologically, CAA was associated with varying degrees of inflammation ranging from none to transmural granulomatous infiltration.	14872042
ARCN1 gene, Inflammation	Altered Intercellular Communication	In conclusion (1) elevated TNF-alpha levels may be related to increased inflammation in patients, (2) circulating TNF-alpha levels were associated with increased leptin levels and (3) although leptin and nutritional parameters were correlated in the stable COPD patients, the correlation was weaker compared to controls, and during an exacerbation it disappeared completely.	14872110
Airway structure, Bronchial Hyperreactivity	Altered Intercellular Communication	Airway inflammation is an important cause of bronchial hyperresponsiveness.	14872111
Herpes Zoster Ophthalmicus, Inflammation, Vascular Diseases, Congenital Abnormality, Traumatic injury, Glaucoma, CTCAE	Altered Intercellular Communication	It develops mostly in long-standing ocular disease such as chronic inflammation, vascular disorders, glaucoma, trauma, or congenital abnormalities.	14872252
Refractory anemias, Inflammation	Altered Intercellular Communication	The aim of the present study was to analyze whether presentation of the immunodominant epitope of HC gp-39 by shared epitope-positive synovial dendritic cells is a specific event in the development of chronic synovial inflammation in RA.	14872486
Refractory anemias, Inflammation, Synovitis	Altered Intercellular Communication	Histologically, expression of HC gp-39, lymphoid aggregates, CD3, and CD1a as well as the global inflammation score were higher in mAb 12A-positive RA synovium than in mAb 12A-negative synovium, indicating a follicular synovitis in these samples.	14872486
Refractory anemias, Inflammation, Autoimmune reaction	Altered Intercellular Communication	This suggests a contribution to the autoimmune-related tissue inflammation and provides a new and independent tool for the immunopathologic diagnosis of RA.	14872486
Arterial Stiffness, Inflammation, vascular inflammations, Vasculitis, CTCAE	Altered Intercellular Communication	Inflammation and arterial stiffness in systemic vasculitis: a model of vascular inflammation.	14872502
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Endothelial dysfunction is associated with acute and chronic systemic inflammation.	14872502
Inflammation	Altered Intercellular Communication	However, the role of systemic inflammation in arterial stiffening has not been determined.	14872502
Arterial Stiffness, Inflammation, Vasculitis, CTCAE, Avian Sarcoma Viruses	Altered Intercellular Communication	The aim of this study was to investigate the relationship between inflammation and arterial stiffness in patients with antineutrophil cytoplasmic antibody-associated systemic vasculitis (AASV) as a model of systemic inflammation.	14872502
Arterial Stiffness, Inflammation, Avian Sarcoma Viruses	Altered Intercellular Communication	These data indicate that AASV is associated with increased arterial stiffness, and that stiffness correlates with the degree of active inflammation.	14872502
Airway structure, Sleep Apnea, Obstructive	Altered Intercellular Communication	Airway inflammation in patients affected by obstructive sleep apnea syndrome.	14959810
Airway structure, Sleep Apnea, Obstructive	Altered Intercellular Communication	Obstructive sleep apnea syndrome (OSAS) has been shown to be associated to upper airway inflammation.	14959810
Sleep Apnea, Obstructive, Bronchitis	Altered Intercellular Communication	The object of the present study was to establish the presence of bronchial inflammation in OSAS subjects.	14959810
Airway structure, Sleep Apnea, Obstructive	Altered Intercellular Communication	In 16 subjects affected by OSAS, and in 14 healthy volunteers, airway inflammation was detected by the cellular analysis of the induced sputum.	14959810
Sleep Apnea, Obstructive, Bronchitis	Altered Intercellular Communication	OSAS subjects show bronchial inflammation characterized by a significant increase in neutrophils.	14959810
Increased insulin level, Hypertriglyceridemia, Ovarian Hyperandrogenism	Altered Intercellular Communication	On hormonal evaluation she had euglycemic hyperinsulinism accompanying mild hypertriglyceridemia and functional ovarian hyperandrogenism.	14960029
Venous Thrombosis, Lemierre Syndrome, Inflammation, Phylum Fusobacteria	Altered Intercellular Communication	The diagnosis of Lemierre's syndrome was established by ultrasonographical detection of right jugular venous thrombosis and perivascular inflammation together with blood cultures positive for Fusobacteria.	14961428
Granulomatous inflammation, Lymphoma, T-Cell, Cutaneous	Altered Intercellular Communication	While granulomatous inflammation has been previously described in cutaneous T-cell lymphomas, it is rare and is often associated with a delay in the diagnosis and difficulty with clinical staging.	14961908
Granulomatous inflammation	Altered Intercellular Communication	The diagnostic dilemma of finding granulomatous inflammation in a patient with common variable immunodeficiency, and the significance of a single AFB on histology are discussed.	14961910
Inflammation, Peeling of skin, Eczema	Altered Intercellular Communication	Siblings aged 7 and 5 years developed extensive truncal and flexural inflammation and desquamation unresponsive to standard eczema therapy.	14961916
Inflammation	Altered Intercellular Communication	The epidermal phenotype as observed in psoriatic skin results from inflammation and abnormal proliferation and terminal differentiation of keratinocytes.	14962089
Inflammation, Anemia	Altered Intercellular Communication	Possible role of cytokine-induced tryptophan degradation in anaemia of inflammation.	14962250
Inflammation, Autoimmune Diseases, Infection, Anemia, Inflammatory disorder	Altered Intercellular Communication	Anaemia of inflammation (AI) is a frequent complication in patients suffering from chronic inflammatory disorders including infections, autoimmune and malignant disease.	14962250
Inflammation	Altered Intercellular Communication	Magnetic resonance imaging (MRI) of the sternum showed severe inflammation in the sternum and the overlying subcutaneous tissue.	14962254
Inflammation, Thrombosis, Rupture, Fibrous, Dental Plaque	Altered Intercellular Communication	Vulnerable plaque demonstrates intense inflammation in which macrophages secrete matrix metalloproteinases (MMPs) that degrade the fibrous cap, ultimately leading to rupture, in situ thrombosis, and an associated clinical event.	14962945
Rupture, vascular inflammations	Altered Intercellular Communication	Thus, inhibition of MMP activity or more general suppression of vascular inflammation are attractive targets for interventions intended to reduce plaque rupture.	14962945
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	We hypothesized that subantimicrobial doses of doxycycline (SDD) (20 mg twice daily) would benefit patients with coronary artery disease by reducing inflammation and MMP activity and thus possibly prevent coronary plaque rupture events.	14962945
Inflammation, Dental Plaque	Altered Intercellular Communication	SDD appears to exert potentially beneficial effects on inflammation that could promote plaque stability.	14962945
Inflammation, Choroiditis, Abnormal sclera morphology	Altered Intercellular Communication	The annular choroidal detachment was probably caused by severe choroidal inflammation and resistance to scleral outflow because of the scleral abnormality due to inflammation and short axial length.	14963715
Pancreatitis, Chronic	Altered Intercellular Communication	Ten per cent of the BWR patients had a pathologic diagnosis of chronic inflammation/pancreatitis.	14964538
Suppurative inflammation	Altered Intercellular Communication	Morphologically, early and continuous ELT was not associated with signs of severe purulent inflammation and, therefore, produced no early additional, damage to the wall.	14964960
Inflammation, Acute Coronary Syndrome, diabetic	Altered Intercellular Communication	Inflammation appears more evident in diabetic than in non-diabetic patients with acute coronary syndrome.	14966041
Communicable Diseases, Inflammation	Altered Intercellular Communication	The uristatin dipstick test in urine showed acceptable negative predictive values (NPV of up to 93%) for patients without infection or inflammation.	14967161
Communicable Diseases, Inflammation	Altered Intercellular Communication	For those with infection or inflammation, the positive predictive values (PPV) of the dipsticks were lower (up to 57%).	14967161
Communicable Diseases, Inflammation, Respiratory Tract Infections	Altered Intercellular Communication	The uristatin strip was more accurate than the leukocyte and nitrite dipsticks for predicting upper respiratory infections (URI) and C-reactive protein for those with infection or inflammation.	14967161
AMBP gene, Infection	Altered Intercellular Communication	We determined the diagnostic value of the trypsin inhibitor, uristatin, that is commonly found in urine and plasma in patients with infections or inflammations of any kind.	14967161
Cataract, Uveomeningoencephalitic Syndrome, Inflammation	Altered Intercellular Communication	The results show that cataract extraction in patients with VKH syndrome can be safely and successfully performed if there are good preoperative and postoperative control of inflammation, careful surgical planning, and meticulous surgical technique.	14967274
Retinitis, Vitreous inflammatory cells	Altered Intercellular Communication	All patients had vitreous inflammation; retinitis was seen upon examination in 82% of the cases.	14968071
Myocarditis, Cardiomyopathies	Altered Intercellular Communication	This transient increase in left ventricular apical volume may have been caused by myocardial inflammation secondary to "ampulla" cardiomyopathy.	14971617
Cystitis, Pyuria	Altered Intercellular Communication	This technique might be useful in the differential diagnosis of patients with chronic bladder inflammation accompanied by pyuria.	14972506
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Bowel inflammation as measured by fecal calprotectin: a link between lifestyle factors and colorectal cancer risk.	14973103
Inflammatory Bowel Diseases, Acute and chronic inflammation, Malignant Neoplasms	Altered Intercellular Communication	Chronic bowel inflammation predisposes to malignancy in cases of inflammatory bowel disease.	14973103
Inflammation	Altered Intercellular Communication	Little is known about the degree of bowel inflammation in general population and the factors that affect it.	14973103
Inflammation	Altered Intercellular Communication	A stool sample was provided for calprotectin measurement (a marker of bowel inflammation), serum for CRP, and a detailed dietary and lifestyle questionnaire completed.	14973103
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Low-level asymptomatic bowel inflammation may be the link between lifestyle and the pathogenesis of CRC, and circulating proinflammatory cytokines may be part of the mechanism for this link.	14973103
Inflammation, Heart Block	Altered Intercellular Communication	Lip biopsy showed lymphohistocytic granulomatous inflammation typical for MRS. Extensive work-up excluded other causes of the complete heart block.	14975426
Inflammation, Vasculitis, CTCAE, Neoplasms	Altered Intercellular Communication	Prominent smooth muscle cell proliferation and granulation tissue response with inflammation led to misdiagnosis of tumor or vasculitis, respectively, in 11 cases.	14976536
Trachoma , Inflammation	Altered Intercellular Communication	Active trachoma [follicles (TF), intense inflammation (TI) or TF/TI] was found in 20.6% (95% CI: 17.8-23.4%) of the subjects.	14977493
Inflammation, Perforation (observation), Intestinal Obstruction	Altered Intercellular Communication	Among them, only 5% are symptomatic with complications-bleeding, intestinal obstruction, inflammation, and perforation.	14978370
Inflammation	Altered Intercellular Communication	In that case the side-to-side isoperistaltic strictureplasty was soft and was without signs of inflammation or stenosis.	14978615
Arthropathy	Altered Intercellular Communication	Ochronotic peripheral arthropathy generally was degenerative, but joint inflammation was observed in some cases; this could be attributed to an inflammatory reaction of the ochronotic shard in the synovial membrane.	14978662
Inflammation	Altered Intercellular Communication	Inflammation subsided after the puncture, but soon recurred.	14978945
Intermittent Claudication, Electrocardiogram: myocardial infarction (finding), Thrombosis, Inflammation	Altered Intercellular Communication	Relationship between intermittent claudication, inflammation, thrombosis, and recurrent cardiac events among survivors of myocardial infarction.	14980996
Calcified (qualifier), Inflammation	Altered Intercellular Communication	Cardiovascular (CV) calcifications constitute a strong risk marker, and recent studies in continuous ambulatory peritoneal dialysis patients have associated valvular calcifications to inflammation, mortality, and CV events.	14981606
Dermatitis	Altered Intercellular Communication	Tenascin expression also markedly increased in tissue lesions with skin inflammation.	14981900
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Array analysis identified many differentially expressed genes involved in fibrosis, stress response, inflammation, cell adhesion, intracellular and nuclear signaling, and metabolic pathways.	14982484
IL13 gene	Altered Intercellular Communication	Montelukast plus cetirizine in the prophylactic treatment of seasonal allergic rhinitis: influence on clinical symptoms and nasal allergic inflammation.	14982509
ARCN1 gene, Inflammation	Altered Intercellular Communication	COPD is characterized by significant chronic inflammation that is evident not only in the pulmonary compartment but also in the circulation.	14982605
Inflammation, Tissue injury	Altered Intercellular Communication	Uncontrolled activation of matrix metalloproteinases (MMPs) can result in tissue injury and inflammation, yet little is known about the activation of MMPs during orthotopic liver transplantation (OLT).	14983226
Inflammation, Peripheral Arterial Diseases, Atherosclerosis	Altered Intercellular Communication	We investigated the association between serum albumin, traditional cardiovascular risk factors, markers of inflammation and cardiovascular outcome in 515 patients with advanced atherosclerosis and severe peripheral artery disease.	14983239
Airway structure	Altered Intercellular Communication	Ambient pollution may lead to airway inflammation as measured by FE(NO).	14985553
Adenocarcinoma of prostate, Arterial Occlusive Diseases	Altered Intercellular Communication	We conclude that prostatic adenocarcinoma treated with hormonal blockage may promote a complex procoagulant state leading to recurrent occlusive arterial disease, refractory to anticoagulation.	14986183
Thyroiditis	Altered Intercellular Communication	Relations between measurable properties of B-mode ultrasound images of thyroid gland and clinical and laboratory findings in patients with chronic inflammation of thyroid gland were studied.	14986724
Inflammation	Altered Intercellular Communication	In the FRISC II trial, the NT-proBNP level, especially if combined with a marker of inflammation, identified those with the greatest benefit from an early invasive strategy.	14987583
Inflammation, Venous Stroke	Altered Intercellular Communication	Association between inflammation and hemostatic markers in atherothrombotic stroke.	14987914
Inflammation, Atherosclerosis	Altered Intercellular Communication	It has been reported that the influence of fibrinogen on the incidence of ischemic events is related to inflammation processes and reflects an association with advance atherosclerosis.	14987914
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	The results suggest a relation among inflammation markers, fibrinogen and TF in the acute phase of stroke.	14987914
Fibrosis Assessment, Liver carcinoma, Hepatitis, FAM126A gene	Altered Intercellular Communication	To test whether Helicobacter species play a role in the enhancement of liver necro-inflammation and fibrosis and in the development of hepatocellular carcinoma (HCC), we sought DNA sequences of Helicobacter species in liver specimens from patients with viral-related chronic hepatitis, HCC or metastatic liver carcinoma.	14988668
Intraocular inflammation, Panuveitis, Uveitis	Altered Intercellular Communication	Disodium alendronate can cause intraocular inflammation (panuveitis and anterior uveitis), which requires discontinuing the treatment.	14988788
Communicable Diseases, Primary malignant neoplasm, Gastritis	Altered Intercellular Communication	Helicobacter pylori (Hp) infection causes a chronic gastric inflammation, which can lead to peptic ulceration and cancer.	14988821
Inflammation, Hyperplasia	Altered Intercellular Communication	There was hyperplasia of conjunctival epithelium, decrease of elastic fiber and chronic inflammation in patients with conjunctivochalasis.	14989959
Communicable Diseases, Aortitis	Altered Intercellular Communication	Aortitis consists in aortic wall inflammation from infectious or non infectious cause.	14990294
Pain Distress Question, Hemorrhage, Inflammation, Hematoma	Altered Intercellular Communication	The patients are given questionnaires with pain assessment tables and different observations are made: postsurgical pain, pain in the first hour after administration of the analgesic, inflammation, bleeding, hematoma, etc.	14990880
Inflammation, Hemorrhage	Altered Intercellular Communication	It is verified that there is inflammation in most of the interventions, the extractions of the semi-impacted third molars (SITM) present greater bleeding on the first day and the extractions of impacted third molars (ITM) present more bleeding on the third day.	14990880
Inflammation, Carcinoid Tumor	Altered Intercellular Communication	Such lesions have been identified in association with chronic inflammation and the concern is that they may represent a precursor lesion for invasive carcinoid tumors.	14991503
Inflammation, Colitis	Altered Intercellular Communication	Following treatment of his colitis, there was complete resolution of both the inflammation and the microcarcinoids.	14991503
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We then compared the vascularity on the contrast-enhanced harmonic gray scale sonographic images with the pathologic findings (fibrosis and inflammation) in all lesions.	14992356
Inflammation, Fibrosis Assessment, Autoimmune Pancreatitis	Altered Intercellular Communication	The grade of lesion vascularity on the contrast-enhanced harmonic gray scale sonographic images correlated with the pathologic grade of inflammation and inversely correlated with the grade of fibrosis associated with autoimmune pancreatitis.	14992356
Inflammation, Colitis, Collagenous	Altered Intercellular Communication	Vascular endothelial growth factor (VEGF)--a possible mediator of inflammation and mucosal permeability in patients with collagenous colitis.	14992444
Watery diarrhea, Colitis, Collagenous, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Patients with collagenous colitis have watery diarrhea and histopathologically thickened collagen layer with discrete signs of mucosal inflammation.	14992444
Inflammation, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Contrast enhancement is a frequent finding in the clinical setting of suspected myocarditis and is associated with active inflammation defined by histopathology.	14993139
Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	Carotid atherosclerosis is associated with inflammation, malnutrition and intercellular adhesion molecule-1 in patients on continuous ambulatory peritoneal dialysis.	14993495
Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	In CAPD patients, carotid atherosclerosis is associated with markers of inflammation, malnutrition and circulating levels of adhesion molecule ICAM-1.	14993495
Inflammation, Fibrosis Assessment, Heart, Chagas Disease	Altered Intercellular Communication	The extent of inflammation, fibrosis, and progression of chronic Chagas heart disease (cChHD) was associated with persistence of parasite DNA in cardiac lesions of necropsies or explants from Argentinean cChHD patients.	14993635
Inflammation	Altered Intercellular Communication	Tenascin-C (TNC) is an extracellular matrix glycoprotein that increases after inflammation and injury.	14993772
Communicable Diseases, Inflammation	Altered Intercellular Communication	CRP levels in the range suggesting a source of infection or inflammation (>10 mg/l) are more common among obese subjects than in nonobese subjects.	14993913
Refractory anemias, Rheumatoid Arthritis, Degenerative polyarthritis	Altered Intercellular Communication	OPG expression was examined by Northern blot hybridization and reverse transcriptase-polymerase chain reaction in synovial fibroblasts from patients with rheumatoid arthritis (RA) and osteoarthritis (OA) and subjects with no inflammatory condition.	14994384
Refractory anemias, Inflammation	Altered Intercellular Communication	Chronic exposure to inflammation in RA suggests a decrease in the GC sensitivity of peripheral lymphocytes.	14994389
Inflammation, Hypertension, CTCAE, Coronary Artery Disease	Altered Intercellular Communication	We sought to assess the relation between circulating levels of inflammation markers, such as neopterin and C-reactive protein, and the development of adverse cardiovascular events in patients with hypertension but without obstructive coronary artery disease.	14996595
Eosinophilic esophagitis	Altered Intercellular Communication	Eosinophilic esophagitis is an inflammatory condition in which there is dense eosinophilic infiltration of the surface lining of the esophagus.	14997131
Inflammation, Damage, Primary demyelination, Immune-mediated	Altered Intercellular Communication	Multiple sclerosis is considered to be an immune-mediated disease of the central nervous system, characterized by chronic inflammation, primary demyelination and axonal damage.	14997936
Radiculitis, Pain Distress Question, Inflammation, Fever, CTCAE, Back Pain	Altered Intercellular Communication	She was readmitted with fever, backache, and pain in the lower limbs, with signs of radiculitis but no indication of inflammation or pain at the site of puncture.	14998150
Inflammation	Altered Intercellular Communication	Although the underlying pathophysiologic mechanisms remain unclear, it has been hypothesized that altered autonomic function and pulmonary/systemic inflammation may play a role.	14998750
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	On multivariate analysis, age, serum alanine aminotransferase (ALT), and histological inflammation were the independent predictors of fibrosis (P = <.0001,.0003, <.0001, respectively).	14999703
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Age, serum ALT, and inflammation are independently associated with fibrosis in multivariate analysis, highlighting the fact that variables other than alcohol intake predominate in the production of hepatic fibrosis.	14999703
Chronic inflammation, Focal Nodular Hyperplasia, Neoplasms, Necrosis	Altered Intercellular Communication	The postoperative diagnosis was neoplasia in 4 cases, noncellular necrosis with chronic inflammation in one case and focal nodular hyperplasia in another case.	14999956
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	having fibrosis stage II or more, or fibrosis stage I with inflammation grade II or more.	15000279
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	dLDLs are associated with platelet-activating factor acetyl hydrolase (PAF-AH), an enzyme involved in inflammation and related to coronary artery disease (CAD).	15001601
Malignant neoplasm of endometrium	Altered Intercellular Communication	Nuclear distribution may be an important component of gene regulation in target tissues, and disruptions in PR distribution in endometrial cancer could affect the function of PR and contribute to aberrant hormonal responses.	15001645
Intraocular inflammation, Complication Aspects, Macular degeneration, Cataract, Glaucoma, CTCAE	Altered Intercellular Communication	The ocular complications most frequently observed at 5 years were cataract (50.3%), maculopathy (18.3%), intraocular inflammation (19.3%), and glaucoma (10.6%).	15002010
Intraocular inflammation, Neoplasms	Altered Intercellular Communication	Risk factors for intraocular inflammation were tumour thickness of more than 4 mm and invasion of the ciliary body.	15002010
Skin necrosis, Inflammation	Altered Intercellular Communication	The transversal arch of the foot gradually declines due to the inflammation, the metatarsal heads protrude in the sole of the foot which is accompanied by painful bunions and sometimes also skin necrosis.	15002348
Chronic lymphocytic inflammation, Chronic Spontaneous Urticaria	Altered Intercellular Communication	The marked female predominance in cases of idiopathic chronic cough and its association with mild chronic lymphocytic airway inflammation suggests an underlying autoimmune process.	15002760
Lupus Nephritis	Altered Intercellular Communication	We propose that this anomalous IgG plays an essential role in the pathogenesis of lupus nephritis and other related inflammatory conditions.	15003811
Inflammation, Necrosis	Altered Intercellular Communication	In addition to these, centrilobular alterations such as central vein endothelialitis, zone 3 inflammation, and hepatocyte necrosis may also be seen during episodes of acute rejection.	15004763
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a multifactorial disorder characterized by irreversible airflow obstruction due to chronic inflammation.	15004839
Inflammation, Bacterial Infections	Altered Intercellular Communication	Procalcitonin (PCT) is a newly introduced marker of systemic inflammation and bacterial infection.	15004865
Inflammation, Compression, Optic Atrophy, Traumatic injury	Altered Intercellular Communication	Ten patients with optic nerve atrophy induced by compression, trauma, or inflammation were examined.	15006846
Inflammation, S100A4 protein, human	Altered Intercellular Communication	Carbohydrate chains of glycoproteins are often altered during malignant transformation or inflammation.	15007307
Airway structure, Asthma	Altered Intercellular Communication	The IL12B gene encodes the p40 chain of IL-12, a proinflammatory cytokine that antagonizes TH2 expression and hence may play a critical role in the pathogenesis of airway inflammation observed in asthma.	15007350
Inflammation, Thrombosis	Altered Intercellular Communication	Color Doppler ultrasonography demonstrated thrombosis of the right internal jugular vein and a CT-scan showed a right sided cervical phlegmonous soft tissue inflammation originating from the right oropharynx.	15007520
Inflammation, immunoglobulin A	Altered Intercellular Communication	The findings suggest that serum IgA changes reflect mucosal inflammation anywhere in the GI tract but that salivary IgA changes reflect involvement of the oral cavity.	15008983
Vascular insufficiency of intestine, Inflammation, immunoglobulin A	Altered Intercellular Communication	These findings suggest that raised serum IgA antibodies to S. cerevisiae may reflect gut inflammation while raised SIgA antibodies to S. cerevisiae or raised IgA or IgA2 levels in saliva reflect oral but not gut disease.	15008983
Inflammation, Primary malignant neoplasm, Tuberculosis, Pneumonia	Altered Intercellular Communication	Here, we study the potential role of the eicosanoid metabolite leukotriene B4 (LTB4) in disparate diseases leading to acute (pneumonia) or chronic (tuberculosis, cancer) inflammation of the pleural space.	15008988
Airway structure, Inflammation, Cystic Fibrosis	Altered Intercellular Communication	It is well documented that patients with cystic fibrosis (CF) are unable to clear persistent airway infections in spite of strong local inflammation, suggesting a dysregulation of immunity in CF.	15008989
Testicular Feminization	Altered Intercellular Communication	Physical and hormonal examinations as well as chromosomal analysis led to a diagnosis of testicular feminization.	15009613
Inflammation	Altered Intercellular Communication	Proopiomelanocortin-derived neuropeptides, such as alpha-melanocyte-stimulating hormone may therefore play an important part in modulating ultraviolet-induced inflammation.	15009732
Inflammation	Altered Intercellular Communication	Proopiomelanocortin-derived neuropeptides, such as alpha-melanocyte-stimulating hormone may therefore play an important part in modulating ultraviolet-induced inflammation.	15009732
Microalbuminuria, Inflammation, Malignant neoplasm of testis, Atherosclerosis	Altered Intercellular Communication	Microalbuminuria, decreased fibrinolysis, and inflammation as early signs of atherosclerosis in long-term survivors of disseminated testicular cancer.	15010071
Inflammation, Visual Impairment, Uveitis	Altered Intercellular Communication	Uveitis is an inflammation of the uveal tract and is one of the major causes of visual impairment.	15010290
Intraocular inflammation	Altered Intercellular Communication	Clinical signs of intraocular inflammation of both eyes were encountered in 71.4% of patients.	15011301
Immunology, IGA Glomerulonephritis, Inflammation	Altered Intercellular Communication	This study suggests that pro-inflammatory, Th1/Th2 cytokines and chemokines are involved in the specific processes of inflammation and immunological injury in IgA nephropathy.	15012746
Communicable Diseases, Inflammation, Ear Inflammation	Altered Intercellular Communication	Otitis externa (OE), also known as "swimmer's ear", is an inflammation or infection of the external auditory canal.	15013609
Familial Mediterranean Fever, Fever, CTCAE, Chest Pain, Brucellosis, Autosomal Recessive Disorder, Abdominal Pain, Arthritis	Altered Intercellular Communication	Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by recurrent and self-limited attacks of serosal inflammation with abdominal pain, chest pain, and arthritis usually accompanied by fever.	15015067
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation and the recruitment of monocytes into the artery wall are thought to be important aspects in the initiation and progression of atherosclerosis.	15015151
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Cardiovascular disease in renal allograft recipients is associated with elevated sialic acid or markers of inflammation.	15016136
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	We wished to examine the relationship between markers of inflammation and CVD in stable renal transplant patients.	15016136
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	This study suggests that inflammation is associated with a higher prevalence of cardiovascular disease in patients with renal allografts.	15016136
Inflammation, Dental Plaque	Altered Intercellular Communication	Immediately following FPD placement, a baseline examination was performed that included assessment of plaque, soft-tissue inflammation and bone level.	15016259
Inflammation, Phlebitis	Altered Intercellular Communication	Idiopathic duct-centric CP (IDCP) (n = 12) had neutrophil-predominant lobular inflammation, without phlebitis.	15017505
Inflammation, Dyspepsia	Altered Intercellular Communication	Mast cells are increased in functional dyspepsia, independently of inflammation.	15017654
Inflammation, Fibrosis Assessment, Diverticulosis, Adenocarcinoma, Diverticulum	Altered Intercellular Communication	Several aspects of diverticulosis were detected: prediverticulosis (3%); global (55.6%); and focal wall thickening (4%) caused by thickened haustral folds, fibrosis, inflammation and adenocarcinoma; diverticula (52%); pseudopolypoid lesions caused by diverticular fecaliths (39%); inverted diverticula (1.2%); and mucosal prolapse (0.6%).	15018168
Inflammation, Specimen Type - Fistula	Altered Intercellular Communication	The place of entry of the inflammation was a 1 x 3 mm subconjunctival fistula in the corneoscleral scar.	15022009
Inflammation	Altered Intercellular Communication	This raises the possibility that in certain circumstances, cytokines such as interleukin-1 (IL-1) may dominate the drive toward joint inflammation.	15022311
Inflammation, Damage, Fatty degeneration	Altered Intercellular Communication	The biopsies had a variety of histologic changes, including steatosis, anisonucleosis, multinucleation, chronic inflammation, bile duct damage, and ductular reaction.	15023035
Inflammation, Asthma	Altered Intercellular Communication	Activated eosinophils play a critical role in asthma pathogenesis, and eosinophil cationic protein (ECP) is a useful indicator of inflammation.	15025036
Stomach Carcinoma, Gastritis	Altered Intercellular Communication	It is also revealed that the expression of TGFalpha and cyclin E were closely associated (P< 0.001 for the tissue of gastric chronic inflammation, and P=0.005 for gastric carcinoma, respectively).	15025953
Pharyngitis, Carcinoma	Altered Intercellular Communication	Immunohistochemical method was used to determine the expression of DeltaNp63 in 60 cases of NPC, 37 cases of nearby mucosa of the carcinoma, and 30 cases of chronic inflammation of nasopharyngeal mucosa.	15025959
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Chronic inflammation mucosas and cancer nearby mucosas showed positive reaction only in their basal and superbasal cells.	15025959
Tumor necrosis, Inflammation	Altered Intercellular Communication	The tumor necrosis factor alpha (TNFalpha) gene plays an important role in immunology and inflammation.	15027477
Airway structure	Altered Intercellular Communication	Asthma is associated with an increase in airway blood flow (Qaw), presumably as a manifestation of airway inflammation.	15028562
Angiodysplasia, Inflammation, Melena, Hypertension, CTCAE	Altered Intercellular Communication	Of the eight patients with melaena, two had angiodysplasia, one showed a diffuse inflammation of the jejunum and ileum probably related to associated portal hypertension, and five had a normal examination.	15028973
Inflammation	Altered Intercellular Communication	The role of opportunistic microflora as pathogens of ENT inflammation is growing as well as the percentage of anaerobic microorganisms detected chromato-mass-spectrometrically in chronic inflammation.	15029124
Inflammation, Atherosclerosis	Altered Intercellular Communication	To assess morphological manifestations of inflammation at initial stages of atherosclerosis development in intima of the aorta and pulmonary artery both in its intact (lipid free) zones and those with lipoidosis.	15029135
Hidradenitis Suppurativa, Inflammation	Altered Intercellular Communication	Acne inversa is an inflammation of the sebaceous glands and terminal hair follicles, chiefly in the intertriginous areas.	15029431
Inflammation, Pustulosis of Palms and Soles, Psoriasis, Hidradenitis Suppurativa, Acne Vulgaris, Dermatitis, Atopic, Thromboangiitis Obliterans, Lupus Erythematosus	Altered Intercellular Communication	The immunological effects, such as the induction of an inflammation reaction play a role in palmoplantar pustulosis, psoriasis, atopic dermatitis, acne vulgaris, acne inversa, thromboangiitis obliterans and lupus erythematodes.	15029439
Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation following endotamponade with high-density silicone oil.	15029505
Intraocular inflammation	Altered Intercellular Communication	One to eight weeks following vitrectomy with high-density silicone oil, an intraocular inflammation was observed in 7 of 19 eyes (37%).	15029505
Dermatitis, Eczema	Altered Intercellular Communication	Hand dermatitis is an eczematous inflammation of the hands that is related to occupation or to routine activities.	15030340
Heart Diseases, Inflammation	Altered Intercellular Communication	Increased heart rate and reduced heart-rate variability are associated with subclinical inflammation in middle-aged and elderly subjects with no apparent heart disease.	15033247
Inflammation	Altered Intercellular Communication	Increased heart rate and reduced heart-rate variability are associated with subclinical inflammation in healthy middle-aged and elderly subjects.	15033247
Inflammation, Glomerulonephritis, Necrosis	Altered Intercellular Communication	MMP-2-, MMP-3-, MMP-9- and TIMP-1-positive cells were detected in ANCA-associated glomerulonephritis in glomeruli with active inflammation (cellular crescents or fibrinoid necrosis), only occasionally in normal appearing glomeruli, and not in sclerotic glomeruli and positive cells were found in the tubulo-interstitium.	15034162
Glomerulonephritis	Altered Intercellular Communication	Expression of matrix metalloproteinases (MMPs) by infiltrating and intrinsic renal cells is increased in inflammatory conditions, and may correlate with disease activity of glomerulonephritis.	15034162
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, peptones	Altered Intercellular Communication	As little information was available about resistin determination in venous blood at the time of our study, we focused on the question whether any correlation exists between persons with type 2 diabetes mellitus, with systemic inflammation, healthy persons and resistin concentrations and laboratory markers of inflammation, peptone, BMI.	15034607
Inflammation, Leukocytosis, Demographics Domain, Acute Disease, Inflammatory disorder	Altered Intercellular Communication	Persons under study were divided into 3 groups: group A - with clinical signs of inflammatory disease of respiratory tract, leukocytosis > 10000/ul and CRP concentration > 50 mg/l (n = 35); group B - with well controlled type 2 DM treated by oral antidiabetic drugs, without clinical signs of inflammation and negative case history of acute disease (n = 12); group C - without clinical signs of inflammation and negative case history of acute disease (n = 77).	15034607
Inflammation, Inflammatory disorder	Altered Intercellular Communication	In patients with severe inflammatory disease a correlation between resistin concentration and laboratory markers of inflammation was shown, however, no correlation was found between leptin and resistin.	15034607
Presenile dementia, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Plasma homocysteine and inflammation in elderly patients with cardiovascular disease and dementia.	15036404
vascular inflammations, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Dementia	Altered Intercellular Communication	Increased levels of plasma total homocysteine (tHcy) may play a role in both cardiovascular diseases (CVD) and old-age dementias via enhancement of vascular inflammation.	15036404
vascular inflammations	Altered Intercellular Communication	The results suggest that the association between plasma tHcy and sCRP is more an aspecific reflection of poor health than a specific correlate of vascular inflammation.	15036404
Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Association of type 2 diabetes with cyclooxygenase-mediated inflammation and oxidative stress in an elderly population.	15037525
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus	Altered Intercellular Communication	Involvement of cyclooxygenase (COX)-mediated inflammation in type 2 diabetes has not been studied, and the association between cytokine-mediated inflammation and diabetes is not fully clarified.	15037525
Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	This is the first study to show that type 2 diabetes in elderly men is related to COX-mediated inflammation, reflected by enhanced prostaglandin formation.	15037525
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	The results further suggest that the appearance of chronic inflammation is an early process in the pathogenesis of diabetes, whereas oxidative injury may be a later process, possibly related to inflammation.	15037525
Inflammation, Pouchitis, Small bowel obstruction	Altered Intercellular Communication	Repeated episodes of pouchitis and partial small-bowel obstruction led to pouchoscopy and pouchography, which demonstrated pouch inflammation and a long, tight, midpouch stricture.	15037928
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Inflammation, coagulation, and depressive symptomatology in cardiovascular disease-free people; the ATTICA study.	15039129
Inflammation, Depression, CTCAE, Coronary heart disease, Bipolar Disorder	Altered Intercellular Communication	This study revealed that depression was associated with inflammation and coagulation factors in cardiovascular disease-free people, suggesting a possible pathway leading to an increased frequency of events of coronary heart disease in depressive individuals.	15039129
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	Studies of animal models have shown that the activation of the complement system could have a role in chronic obstructive pulmonary disease (COPD) and asthma by promoting inflammation and enhancing airway hyperresponsiveness.	15039137
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	We sought to determine whether the levels of complement factors C3a, C4a, and C5a are elevated at the site of inflammation in patients with COPD and patients with asthma.	15039137
Vascular anomaly, Inflammation, Neoplasms	Altered Intercellular Communication	The other causes of orbital process, inflammation, tumor or vascular malformation, should be considered in the differential diagnosis.	15039629
Retinal Detachment, Hemorrhage, Papilledema, Vitreous inflammatory cells	Altered Intercellular Communication	Posterior segment examination on the left eye showed an optic disk edema with papillary and peripapillary hemorrhages and serous retinal detachment, mild vitreous inflammation, and two little perivascular white spots.	15039632
Refractory anemias, Rheumatoid Arthritis, Degenerative polyarthritis	Altered Intercellular Communication	Immunostaining for CXCL12 on synovial and bone tissue biopsies from both rheumatoid arthritis (RA) and osteoarthritis (OA) samples revealed a strong increase in the expression levels under inflammatory conditions.	15040007
Primary Biliary Cholangitis, Intrahepatic bile duct	Altered Intercellular Communication	Primary biliary cirrhosis (PBC) is a chronic, cholestatic disease of autoimmune etiology, the histology of which shows a destruction of the intrahepatic bile duct and portal inflammation.	15040040
Inflammation, Takayasu Arteritis, Inflammatory disorder	Altered Intercellular Communication	Takayasu's arteritis is a chronic inflammatory disease of unknown origin in which cell-mediated inflammation involves large arteries progressing from the adventitia to the intima, until the lumen of the vessel is narrowed.	15042394
Chronic Kidney Diseases	Altered Intercellular Communication	Resistance training to reduce the malnutrition-inflammation complex syndrome of chronic kidney disease.	15042537
Inflammation, Protein-Energy Malnutrition, Kidney Diseases	Altered Intercellular Communication	Systemic inflammation and protein-energy malnutrition may be associated with poor outcomes in kidney disease.	15042537
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Resistance training reduced inflammation and improved nutritional status in individuals with moderate chronic kidney disease consuming a low-protein diet.	15042537
Inflammation, GDC Comorbidity Terminology	Altered Intercellular Communication	This reverse association remained significant in a subcohort of 322 MHD patients after additional adjustments for comorbid conditions and serum C-reactive protein level to reflect inflammation.	15042544
Inflammation, GDC Comorbidity Terminology	Altered Intercellular Communication	Low baseline serum iron indicators are associated with increased mortality and hospitalization in MHD patients independent of hemoglobin level, EPO and iron doses, indicators of nutrition and inflammation, and comorbid conditions.	15042544
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation is common in patients with chronic renal failure and has been associated with the increased risk for cardiovascular disease (CVD) in this condition.	15042546
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Patterns of inflammation in mucosal biopsies of ulcerative colitis: perceived differences in pediatric populations are limited to children younger than 10 years.	15043307
Inflammation, Distortion	Altered Intercellular Communication	As children approach adulthood, the degree of inflammation and architectural distortion seen is similar to that found in adults.	15043307
Inflammation, Helicobacter pylori, Atrophic, Metaplasia	Altered Intercellular Communication	There were no significant differences in histopathologic findings with respect to inflammation, atrophy, metaplasia, or Helicobacter pylori scores between the two groups.	15044886
Inflammation, Ulcer	Altered Intercellular Communication	Nine patients had large, multiple ulcers with surrounding inflammation.	15044887
Allergic sensitization, Gastritis	Altered Intercellular Communication	This phenomenon may contribute to the maintenance of gastric inflammation and could play a role in the development of allergic sensitization to dietary antigens in susceptible individuals.	15046209
Crohn Disease, Inflammation, Inflammatory disorder	Altered Intercellular Communication	Crohn's disease is a chronic inflammatory disorder characterized by focal, transmural inflammation of the intestine.	15047250
Inflammation, Atherosclerosis, Diabetes Mellitus	Altered Intercellular Communication	Preclinical atherosclerosis and inflammation in 61-year-old men with newly diagnosed diabetes and established diabetes.	15047642
Inflammation, Dental Plaque, atherosclerotic, Diabetes Mellitus	Altered Intercellular Communication	This is the first study to show increased preclinical atherosclerotic changes (IMT and plaque size) and increased inflammation (hs-CRP) in men with newly diagnosed diabetes as well as in patients with established diabetes compared with healthy control subjects.	15047642
Inflammation, Hepatitis, Fibrosis Assessment, Fatty degeneration, Non-cirrhotic	Altered Intercellular Communication	On multivariate analysis of non-cirrhotic biopsies, steatosis was associated with increasing patient age and remained significantly associated with fibrosis independent of portal inflammation and interface hepatitis.	15047745
ARCN1 gene, Abnormal renal function, Inflammatory disorder, Airway structure	Altered Intercellular Communication	COPD is an inflammatory disorder characterised by chronic airflow limitation, but the extent to which airway inflammation is related to functional abnormalities is still uncertain.	15047950
Inflammation, Fibrosis Assessment, Fatty degeneration, Cholestasis	Altered Intercellular Communication	The following histopathologic features were assessed: CN, steatosis, lobular inflammation, cholestasis, endothelialitis, and fibrosis.	15048789
Inflammation, Cholestasis	Altered Intercellular Communication	The multivariate analysis showed the presence of cholestasis, lobular inflammation, the ALT level, and time since liver transplantation to be independent predictors of the presence of ACR in biopsies with CN.	15048789
Inflammation, Cholestasis	Altered Intercellular Communication	In conclusion, the presence of cholestasis and lobular inflammation on biopsies with CN appeared helpful in predicting its association with ACR.	15048789
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Vasculitis includes a heterogeneous group of multisystemic disorders characterized pathologically by inflammation of blood vessels.	15049171
Hormone abnormality, Traumatic injury, Ionizing radiation	Altered Intercellular Communication	Genetic factors, hormonal disorders, injuries, viral induction and ionizing radiation may play certain role in its developing.	15049197
Inflammation, Acute myocardial infarction, Coronary Arteriosclerosis	Altered Intercellular Communication	Inflammation is an important feature of arteriosclerotic disease, and the vulnerability of coronary plaques in acute myocardial infarction (AMI) may be related to the levels of serum C-reactive proteins (CRP).	15049386
Osteopenia	Altered Intercellular Communication	Age-related decline in IGF-I and gonadal hormones have been postulated to play an important role in the pathogenesis of age-related bone loss in men.	15049965
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histology revealed homogeneous foreign body inclusions (silicone) with fibrosis, chronic inflammation and multinuclear giant cells.	15050078
Inflammation, Swelling	Altered Intercellular Communication	Evidence of inflammation of the knee and a hard swelling in the subquadricipital area were the main physical findings.	15050200
Inflammation	Altered Intercellular Communication	Therefore, C- genotype is coupled with chronic inflammation, impaired immune efficiency, low zinc ion bioavailability and high MTmRNA.	15050298
Cataract, Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Age of onset, type of inflammation, incidence of secondary glaucoma, and surgical history of glaucoma and cataract did not differ between the 1980s and the 1990s.	15051217
Inflammation, Weight decreased	Altered Intercellular Communication	Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial.	15051595
Inflammation, Chronic disease	Altered Intercellular Communication	Persistent, low-grade inflammation is an independent predictor of several chronic diseases and all-cause mortality.	15051595
Inflammation, Weight decreased	Altered Intercellular Communication	The intention of this study was to determine the independent and combined effects of diet-induced weight loss and exercise on markers of chronic inflammation.	15051595
Inflammation, Weight decreased	Altered Intercellular Communication	These findings provide evidence from a randomized controlled trial that a dietary intervention designed to elicit weight loss reduces overall inflammation in older, obese persons.	15051595
Inflammation	Altered Intercellular Communication	Systemic inflammation may be involved in the pathogenesis of such conditions; however, relations between TFA intake and systemic inflammation are not well established.	15051604
Inflammation, F3 wt Allele, Coronary heart disease, Diabetes Mellitus	Altered Intercellular Communication	Further investigation of the influences of TFAs on inflammation and of implications for coronary disease, diabetes, and other conditions is warranted.	15051604
Inflammation, Pericarditis, CTCAE, Pericarditis, Constrictive	Altered Intercellular Communication	The histopathological examination revealed degenerative changes of myocardium without significant inflammation, indicating that surgical pericardiectomy should be performed for subacute effusive-constrictive pericarditis before progression to definite constrictive pericarditis.	15054551
Inflammation	Altered Intercellular Communication	Routine laboratory investigations confirmed the presence of inflammation.	15054952
Gingivitis, refracture	Altered Intercellular Communication	Eight cases failed to respond to treatment because of refracture, recurrence of gingival inflammation, or both.	15055431
Inflammation, Thrombus	Altered Intercellular Communication	Their association with local inflammation could favor thrombotic events in the liver micro-circulatory bed.	15056097
Connective Tissue Diseases, Myocardial Ischemia	Altered Intercellular Communication	Connective tissue disease, which is an inflammatory condition represented by C-reactive protein (CRP), is a risk factor for ischemic heart disease.	15056836
Angina, Unstable, Connective Tissue Diseases, Angina Pectoris, Variant	Altered Intercellular Communication	Coronary spastic angina is a frequent complication in patients with connective tissue disease and the inflammatory condition is associated with coronary spastic angina and unstable angina in patients with connective tissue disease.	15056836
Inflammation	Altered Intercellular Communication	Histologically, all specimens showed a thinned and spongiotic epithelium, a band-like infiltrate of lymphocytes and histiocytes with a variable number of plasma cells in the upper part of the chorion and further signs of acute, subacute or chronic inflammation.	15057000
Sepsis	Altered Intercellular Communication	Many studies show important disturbances in hormonal balance in patients with severe sepsis.	15058038
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Chronic inflammation may contribute to cancer risk through the accumulation of specific products as a result of DNA damage.	15058522
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The role of free radical mediated oxidative DNA damage during inflammation was determined in patients with ulcerative colitis by measuring 8-hydroxydeoxyguanosine (8-OHdG).	15058522
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Patients with ulcerative colitis were compared according to age, gender, duration and extent of disease, endoscopic and histologic activity, presence or absence of dysplasia/cancer, and biochemical parameters of inflammation.	15058522
Inflammation	Altered Intercellular Communication	[Relation between inflammation related cytokines and myocardial microcirculatory reperfusion state].	15059405
Inflammation, Choroidal Detachment	Altered Intercellular Communication	The complications such as flat chamber, inflammation and choroidal detachment were not observed.	15059556
Inflammation, Bacterial Infections	Altered Intercellular Communication	Children with typical bacterial or mixed bacterial/viral infections had the greatest inflammation and disease severity.	15060215
Inflammation, Venous Insufficiency, dystrophic	Altered Intercellular Communication	Impaired microcirculation in chronic venous insufficiency leads to chronic inflammation and dystrophic changes of the skin, and finally to leg ulceration.	15061043
Inflammation, Coronary heart disease	Altered Intercellular Communication	The extinction of those birth cohorts would result in a relative increase in cases coming from a 2nd subpopulation, which was characterized by insulin resistance and chronic expression of low-grade inflammation markers and was comparatively less vulnerable to die acutely from coronary heart disease.	15061621
Inflammation	Altered Intercellular Communication	Various evidence suggests an additional therapeutic potential in regard to inflammation and immunomodulation.	15061967
Neurodegeneration due to 3-hydroxyisobutyryl coenzyme A hydrolase deficiency, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	However, the hypothesis that pro-inflammatory cytokine-induced systemic inflammation is an early metabolic defect prior to onset of type 2 diabetes, is not supported in our study of elderly Korean women.	15063602
Inflammation, Restenosis	Altered Intercellular Communication	Inflammation has been postulated to be a major contributor to restenosis after angioplasty.	15064103
Inflammation, Prostate carcinoma	Altered Intercellular Communication	We evaluated the association of pre-diagnostic plasma concentration of C-reactive protein, a sensitive, but non-specific indicator of inflammation, with subsequent risk of prostate cancer.	15065087
Inflammation, Attachment (action), Periodontal Diseases, Hemorrhage	Altered Intercellular Communication	Periodontal disease was measured as mean pocket depth and attachment loss, extent (percentage) of pockets with at least 6 mm probing depth, extent of bleeding on probing, and tissue inflammation.	15066069
Neoplasms	Altered Intercellular Communication	In the absence of a dominant nodule, DSVPTC can be histologically deceiving because of exuberant inflammation and the scattered distribution of the microscopic tumor islands.	15067179
Tumor necrosis, Inflammation	Altered Intercellular Communication	The tumor necrosis factor (TNF) is an important cytokine of cellular response and inflammation.	15068388
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is a condition characterized by chronic inflammation targeted at the epithelial layer.	15068964
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In conclusion, in the absence of inflammation, UC colonocytes exhibit an mtDNA deletion pattern similar to that of control cells, indicating a normal response to physiological levels of oxidative stress.	15068964
Inflammation	Altered Intercellular Communication	In active inflammation, when oxidative stress increases, the frequency, variety, and number of mtDNA deletions decrease.	15068964
Ulcerative Colitis	Altered Intercellular Communication	Because comparable abnormalities are absent in active CD, the mtDNA deletion pattern of active UC suggests that colonocytes respond uniquely to inflammation-associated stress in this condition.	15068964
Inflammation, Adenoma, Carcinoma of lung	Altered Intercellular Communication	We present a patient with a history of lung cancer and FDG accumulation in a benign adenoma, probably reflecting areas of chronic inflammation also seen within the gland at pathology.	15069328
Polyarteritis Nodosa, Giant Cell Arteritis, Inflammation	Altered Intercellular Communication	Rarely, such changes are due to inflammation of the blood vessels, such as occurs in polyarteritis nodosa or giant cell arteritis.	15069628
Inflammation, Coronary heart disease	Altered Intercellular Communication	C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease.	15070788
Degenerative polyarthritis, Inflammation, Joint injury	Altered Intercellular Communication	They may help explain the increased risk of osteoarthritis with age and after joint trauma and inflammation, and suggest that minimizing oxidative damage will help produce optimal results for chondrocyte transplantation.	15071075
Inflammation, Carotid Stenosis	Altered Intercellular Communication	A case-control study was conducted to determine: (1) possible association between biomarkers of angiogenesis or inflammation and carotid stenosis; and (2) the impact of revascularization on the same biomarkers.	15072994
Inflammation, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	p16INK4A overexpression was significantly higher in CIN (75%) and in SCC (75%) than in normal or inflammation of the cervix (12.5%; P < 0.01, P < 0.05, respectively).	15073118
Inflammation, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	PCNA expression was negative in normal or inflammation of the cervix, but an increased in expression was seen in 63.2% in CIN and 100% in SCC (P < 0.01, P < 0.05).	15073118
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Histological moderate to severe mucosal inflammation was present in 78% (33/42) of the patients, however, and rectal stump involution was noted in 43% (18/42).	15074392
Inflammatory Bowel Diseases, Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Although this is reassuring for patients, the presence of moderate to severe inflammation in the majority of rectal stumps indicates a role for adjuvant molecular markers to improve colorectal cancer surveillance on this subgroup of IBD patients.	15074392
Pancreatitis, Acute, Fibrosis Assessment, Injury of pancreas, Traumatic injury	Altered Intercellular Communication	Cytokines are markers of acute pancreatic inflammation and essential for distant organ injury, but they also stimulate pancreatic fibrogenesis and are thus involved in the progression from acute pancreatitis to chronic pancreatic injury and fibrosis.	15074399
Inflammation	Altered Intercellular Communication	Examination of the brain parenchyma showed scattered microglial aggregates accompanied by perivascular chronic inflammation.	15074579
Inflammation, Pigmented villonodular synovitis	Altered Intercellular Communication	Iron pigment deposition and inflammation are mild to absent, making synovial excrescences different from pigmented villonodular synovitis.	15074582
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	This study was undertaken to investigate the presence of different semaphorins in synovial tissue of patients with RA, patients with osteoarthritis (OA), and control subjects without inflammation.	15077297
Ancriviroc, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	The grade of inflammation and the stage of fibrosis of CH-C showed no associations with either the IFN-gamma or IL-10 promoter polymorphisms or with Con A-stimulated IL-10 or IFN-gamma production.	15078471
Ancriviroc, Inflammation, Hepatitis C	Altered Intercellular Communication	On multivariate analysis, the grade of inflammation and the duration of HCV infection accounted for only 37% of the variance in the stage of CH-C (P<0.0001).	15078471
Inflammation, Superficial ulcer, Retinal Detachment, Communicable Diseases, Pathologic Neovascularization	Altered Intercellular Communication	No patient showed signs of implant rejection, infection, inflammation, erosion, neovascularization, retinal detachment, or migration.	15078662
Dental Plaque	Altered Intercellular Communication	In addition to anticoagulation, endothelial protein C receptor may play an important inflammation-related role in plaque development.	15080580
Ovarian Teratoma, Struma Ovarii	Altered Intercellular Communication	Struma ovarii is an ovarian teratoma and constitutes a rare cause of ectopic thyroidal hormonal production.	15080771
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation in asthma is associated with cysteinyl leukotriene and prostaglandin D(2) production.	15080817
Hormone abnormality, Erectile dysfunction	Altered Intercellular Communication	Recent evidence indicate that approximately 10-20% of men with erectile dysfunction (ED) have hormonal abnormalities, raising up to 35% over the age of sixty.	15082192
Inflammation, Traumatic injury	Altered Intercellular Communication	In response to stimuli such inflammation and trauma, mast cells degranulate and consequently release heparin.	15082291
Inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	No significant alteration of the HPA axis was found in patients with SLE, which is inadequate in view of the continuing inflammation.	15082470
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	To analyse the effect of infliximab on the immunopathology of rheumatoid nodules in order to provide new insights into the relationship between synovial inflammation and rheumatoid nodules.	15082477
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Mucosal inflammation in inflammatory bowel disease is associated with loss of normal anaerobic bacteria.	15082587
Cessation of life, Inflammation, Fatty Liver	Altered Intercellular Communication	The present study examined the risk of development of cirrhotic liver disease and the risk of death in a cohort diagnosed with pure fatty liver without inflammation.	15082596
Inflammation, Fibrous, Primary acquired nasolacrimal duct obstruction	Altered Intercellular Communication	The success rate of nasolacrimal polyurethane stent implantation for the treatment of primary acquired nasolacrimal duct obstruction is low and may induce inflammation and fibrous tissue formation.	15083082
Noninfiltrating Intraductal Carcinoma, Inflammation, Necrosis	Altered Intercellular Communication	Other features that showed moderate or strong agreement between the original and recurrent DCIS were necrosis and periductal inflammation.	15083182
Inflammation, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	Altered Intercellular Communication	Axonal pathology has been related to the inflammatory demyelinating environment, but its dependence on inflammation is still unknown.	15083285
Inflammation, Damage	Altered Intercellular Communication	These findings strengthen the hypothesis that inflammation may be at least in part responsible for the axonal damage observed in MS patients.	15083285
Pain Distress Question, Inflammation, Tooth structure	Altered Intercellular Communication	The patients exhibited neither preoperative pain nor inflammation (tooth extractions) and when pain occurred received as alternative medication diclofenac retard 50 mg or tramadol.	15083355
Pneumonitis, Chronic lung disease	Altered Intercellular Communication	Effect of inhaled corticosteroids on markers of pulmonary inflammation and lung maturation in preterm infants with evolving chronic lung disease.	15083986
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	There is increasing evidence that inflammation plays an important role in cardiovascular disease.	15084512
Inflammation, Lymphangiectasis	Altered Intercellular Communication	In all 44 cases, histologic examination disclosed normal conjunctival epithelium and negligible inflammation and lymphocyte infiltration; 39 patients manifested microscopic lymphangiectasia.	15084864
Inflammation	Altered Intercellular Communication	Detection of neutrophils in late-onset interface inflammation associated with flap injury after laser in situ keratomileusis.	15084867
Traumatic	Altered Intercellular Communication	To report a case with late-onset interface inflammation associated with traumatic flap injury at 7 months after laser in situ keratomileusis (LASIK) and to describe the type of infiltrating cells in the tears of the patient.	15084867
Tears body substance, Inflammation	Altered Intercellular Communication	For controls, tears of 2 patients who underwent LASIK and developed no interface inflammation were collected the next day after their surgeries and examined.	15084867
Myocarditis, Ventricular Dysfunction, Left	Altered Intercellular Communication	Histological (Dallas classification) and immunohistological analyses were performed to detect myocardial inflammation in the endomyocardial biopsies.PB19 genomic DNA was found in nine of 80 patients (11.2%), 4 out of 31 (12.9%) patients with inflammatory infiltrates detected via immunohistological methods and 5 out of 49 (10.2%) patients with left ventricular dysfunction without myocardial inflammation.	15085375
Myocarditis, CTCAE 5.0, Virus Diseases, Myocarditis	Altered Intercellular Communication	All biopsies of 36 controls with no history of myocarditis or recent viral infection were negative for myocardial inflammation and parvovirus B19 genomes.	15085375
Ulcer	Altered Intercellular Communication	Inflammation of the corneal stroma was present in the peripheral but absent in the central edge of the ulcer, a characteristic sign of a rodent ulcer.	15085968
Inflammation	Altered Intercellular Communication	We identified neuronophagia, neuronal disappearance, perivascular chronic inflammation, and microglial proliferation in the ventral horns of the spinal cord, especially in the cervical and lumbar segments.	15086282
Inflammation, Acute respiratory failure	Altered Intercellular Communication	Strategies to modulate inflammation must take into account the complex cytokine biology in patients with established ARF.	15086475
Inflammation	Altered Intercellular Communication	This response is associated with evidence of activation of the acute phase response (inflammation) but not with changes in enPCR.	15086482
Inflammation	Altered Intercellular Communication	In well-dialyzed patients, inflammation is the principal cause of a decrease in serum albumin while protein intake plays an insignificant role.	15086482
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Cytokine-orchestrated chronic inflammation plays a major role in long-term morbidity and mortality in patients with end-stage renal disease (ESRD) on hemodialysis (HD).	15086488
Suppuration, Inflammation, Specimen Type - Fistula, Swelling	Altered Intercellular Communication	Further, clinical signs of severe inflammation, such as suppuration, swelling and/or fistula formation were detected in the majority of sites and seven of the 12 implants were found to be mobile at biopsy.	15086615
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The process of atherogenesis involves inflammation and endothelial dysfunction.	15087258
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Inflammation has been implicated as an etiological factor in several human cancers.	15087412
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Growing evidence suggests that chronic inflammation may also play a role in the etiology of prostate cancer.	15087412
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Considering that genetic susceptibility is a major risk factor for this disease, we hypothesize that sequence variants in genes that regulate inflammation may modify individual susceptibility to prostate cancer.	15087412
Craniocerebral Trauma, Brain Neoplasms, Cerebrovascular accident, Orbital Pseudotumor, Craniofacial Abnormalities	Altered Intercellular Communication	The etiologies were likely congenital (n = 56), craniofacial anomalies (n = 12), head trauma (n = 5), postresection of brain tumors (n = 3), orbital inflammation (n = 1), prenatal stroke (n = 1), and unknown (n = 14).	15088046
Retinal Detachment, Intraocular inflammation	Altered Intercellular Communication	A coincident retinal detachment led to a delay in diagnosing the etiology of this intraocular inflammation.	15088829
Inflammation, Intraocular inflammation	Altered Intercellular Communication	After recurrent episodes of inflammation that were initially responsive to corticosteroids, the patient underwent a vitrectomy, lens explantation, capsulectomy, and intravitreal antibiotic injections, which resulted in complete resolution of the intraocular inflammation with a best-corrected visual acuity of 20/60.	15088829
Inflammation, Dental Plaque	Altered Intercellular Communication	Gingival inflammation and plaque accumulation were assessed at baseline and 52 weeks in both groups.	15088886
Cataract, Inflammation	Altered Intercellular Communication	To compare the safety and efficacy of the Surodex dexamethasone anterior segment drug delivery system (Oculex Pharmaceuticals, Inc.) and dexamethasone 0.1% eyedrops (Maxidex) in patients with inflammation after cataract surgery.	15093636
Intraocular inflammation	Altered Intercellular Communication	There were also no significant between-group differences in subjective assessment of intraocular inflammation and in impact on corneal endothelial cell count (P =.67).	15093636
Cataract, Intraocular inflammation	Altered Intercellular Communication	Surodex appeared to be as effective as dexamethasone 0.1% eyedrops in controlling intraocular inflammation after cataract surgery by phacoemulsification, and both methods had a similar safety profile.	15093636
Orbital Pseudotumor, Allergy - Charge Type Reason	Altered Intercellular Communication	Hyaluronidase allergy after peribulbar anesthesia with orbital inflammation.	15093662
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Liver fibrosis, inflammation and necrosis were assessed using the METAVIR score.	15094677
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Bronchoalveolar lavage fluid (BALF) in cystic fibrosis (CF) shows increased inflammation, which could be due to abnormal cytokine regulation.	15095321
Inflammation, Carditis, Cardia of stomach	Altered Intercellular Communication	The aetiology of inflammation of the gastric cardia (carditis) and the concept of the cardia as a native zone of mucinous gastric glands are disputed.	15095855
Intestinal metaplasia, Inflammation, Helicobacter pylori, Atrophic	Altered Intercellular Communication	The degree of inflammation, Helicobacter pylori density, intestinal metaplasia and atrophy were scored according to the Sydney classification and the type of cardiac mucosa (oxyntic or mucinous) was noted.	15095855
Acute anterior uveitis, Uveitis	Altered Intercellular Communication	Raised IOP is significantly more common in patients with chronic intraocular inflammation than those with acute uveitis.	15097253
Inflammation	Altered Intercellular Communication	These symptoms in MS may represent transient phenomena related to inflammation in acute plaques and probably are secondary to irritation of demyelinated axons by lymphokines.	15098339
Inflammation, Epilepsy, CNS disorder	Altered Intercellular Communication	It requires differential diagnosis with other diseases of central nervous system such as epilepsy and neurodegenerative or inflammation pathology.	15098339
Inflammation, Fibrosis Assessment, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	It was believed that the steroid therapy suppressed the progression of the inflammation and fibrosis caused by the chronic myocarditis.	15098603
Inflammation, Chronic disease, Neoplasms	Altered Intercellular Communication	We considered that systemic inflammation or chronic disease, in addition to the tumor, may influence the plasma TGF-beta level.	15102678
Chronic heart failure	Altered Intercellular Communication	Since NPY plasma levels are high in chronic heart failure patients, NPY may be one component leading to impaired parasympathetic neurotransmission in those patients.	15103451
Pancreatitis, Acute, Inflammation	Altered Intercellular Communication	We investigated the effectiveness of scoring systems, acute inflammation and acute phase responses in the early diagnosis of the severity of acute pancreatitis.	15103565
Pain Distress Question, Tissue Adhesions, Inflammation	Altered Intercellular Communication	According to intraoperative findings there were 8 patients with adhesions, 12 with gynecological origin of pain, 27 with chronic inflammation or narrowed lumen of the appendix, and 6 with normal laparoscopic findings and innocent appendix.	15103754
Interstitial inflammation	Altered Intercellular Communication	Leukocyte CD11b and CD62l expression in response to interstitial inflammation in CAPD patients.	15104334
Inflammation, Bulla	Altered Intercellular Communication	After 12 hours, blister exudates were collected and the blisters were thereafter challenged with buffer or autologous serum in order to establish an intermediate and an intense cutaneous inflammation.	15104334
Interstitial inflammation	Altered Intercellular Communication	Furthermore, there were no significant correlations between concentrations of MCP-1 and IL-8 in blister exudates and expression of CD11b on monocytes and granulocytes at the sites of interstitial inflammation.	15104334
Interstitial inflammation	Altered Intercellular Communication	The ability of monocytes and granulocytes to modulate the expression of adhesion molecule in response to interstitial inflammation was significantly impaired in patients on peritoneal dialysis.	15104334
Hepatitis	Altered Intercellular Communication	In contrast, ALT levels were significantly higher in younger (< or = 50 years old) than in older patients only when activity of liver inflammation was severe.	15104373
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	More importantly, a significant number of older patients and patients with severe hepatic fibrosis had severe hepatic inflammation even when their serum ALT level was not markedly elevated (< or = 70 IU/L).	15104373
Proctitis, Inflammation, Toxic effect	Altered Intercellular Communication	Acute grade 2 toxicity was observed in four patients: genitourinal inflammation in 4, and proctitis in 2 cases.	15105901
Tooth Movement Techniques, Pulpitis	Altered Intercellular Communication	It has been reported that substance P (SP) and calcitonin gene-related peptide (CGRP), both sensory neuropeptides, are manifested in the dental pulp of rats during experimental tooth movement, suggesting that they might be involved in the dental pulp inflammation during orthodontic tooth movement.	15105969
Inflammation	Altered Intercellular Communication	The F3-5 epitope may represent a protein that is upregulated during inflammation or point to a yet unrecognised morbillivirus in the human central nervous system that might be implicated in MS pathogenesis.	15106826
Lung Diseases, Obstructive, Bronchitis	Altered Intercellular Communication	[Clinical significance of cytological characteristics of bronchial inflammation in obstructive pulmonary diseases].	15108456
Inflammation, Fibrous	Altered Intercellular Communication	If HRCT detected active inflammation and in development of irreversible fibrous changes TAT was higher vs control.	15108458
Inflammation, Thrombophilia	Altered Intercellular Communication	Stable markers of thrombophilia (TAT and TF-4) reflect activity of inflammation in FA.	15108458
Inflammation, Pathology	Altered Intercellular Communication	Therefore, we examined whether differences in the expression of proinflammatory cytokines by these two distinct vascular pathologies favor the accelerated inflammation within diseased vein grafts.	15111145
Inflammation	Altered Intercellular Communication	Colonoscopic findings were abnormal in 58 patients (76%) showing mostly ulcerations and inflammation of the colon.	15112355
Inflammation, Granuloma	Altered Intercellular Communication	Eighty nine percent of patients showed nonspecific inflammation with chronic inflammatory cells and half of these patients revealed the presence of granulomas and granulations on bowel biopsies.	15112355
Schizophrenia	Altered Intercellular Communication	Gamma-Aminobutyric acid (GABA), the principal inhibitory neurotransmitter of CNS, has been consistently implicated in the pathophysiology of schizophrenia.	15114630
Thrombophilia	Altered Intercellular Communication	Significant hypercoagulation in early postoperative period found in the examinees promoted formation of inflammation-related contaminated dense protein products which serve a source of permanent reinfection.	15114757
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, physiopathological	Altered Intercellular Communication	These results prompted us to study subrogate markers of inflammation or vascular dysfunction in type II diabetic patients.	15116247
Inflammation, Thrombosis, Ischemic stroke	Altered Intercellular Communication	Data were available on 92 polymorphisms from 56 candidate genes related to inflammation, thrombosis and lipid metabolism, assessed in 319 incident cases of ischemic stroke and 2090 disease-free controls.	15116352
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The technique was easy to learn and this new operative technique seems promising especially in cases of inflammation or fibrosis.	15116820
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	Within each histopathological type, 62.7 per cent of patients with eosinophil-dominated inflammation and 81.8 per cent of patients with neutrophil-dominated inflammation had a positive allergy skin test.	15117044
Inflammation, Rhinosinusitis	Altered Intercellular Communication	60.8 per cent of patients with eosinophil-dominated inflammation and 81.8 per cent of patients with neutrophil-dominated inflammation had rhinosinusitis.	15117044
Inflammation, Rhinosinusitis, Nasal Polyps, Allergy - Charge Type Reason	Altered Intercellular Communication	Nasal polyps had association with positive allergy skin test (68.5%), rhinosinusitis (67.1%) and eosinophil-dominated inflammation (69.9%).	15117044
Allergy - Charge Type Reason	Altered Intercellular Communication	There was no statistically significant difference in prevalence of positive allergy skin test between eosinophil- and neutrophil-dominated inflammations (p = 0.107).	15117044
Rhinosinusitis	Altered Intercellular Communication	There was no statistically significant difference in prevalence of rhinosinusitis between eosinophil- and neutrophil-dominated inflammations (p = 0.079).	15117044
Rhinosinusitis, Allergy - Charge Type Reason	Altered Intercellular Communication	There were no statistically significant differences in prevalence of positive allergy skin test and rhinosinusitis between eosinophil- and neutrophil-dominated inflammations (p = 0.107 and p = 0.079, respectively).	15117044
Inflammation, Carcinogenesis	Altered Intercellular Communication	Mucin gene expression is cell- and tissue-specific, with variations during cell differentiation and inflammation, and is altered during carcinogenesis.	15117101
Inflammation, Chronic diarrhea	Altered Intercellular Communication	Gastroenterologists are often hampered by the lack of a reliable, non-invasive index of bowel inflammation when establishing a differential diagnosis for patients presenting with chronic diarrhoea.	15117438
Inflammation, Chronic infectious disease, Diabetes Mellitus	Altered Intercellular Communication	Serum osteoprotegerin showed a strong association with numerous vascular risk factors, including age, diabetes, markers of systemic inflammation, chronic infection, and smoking.	15117849
Inflammation, Granuloma	Altered Intercellular Communication	These findings correspond histopathologically to bronchiolectasis and bronchiolar and peribronchiolar inflammation with or without granuloma formation.	15118112
Coronary Occlusion, Inflammation, Acute myocardial infarction	Altered Intercellular Communication	To elucidate the involvement of inflammation in coronary artery occlusion, the regional changes in cytokines and matrix metalloproteinases (MMPs) in the infarct-related coronary artery were determined in patients with acute myocardial infarction.	15118287
Inflammation, Tumor necrosis	Altered Intercellular Communication	Cytokines associated with brain inflammation such as interleukin (IL)-1beta, IL-6, and tumor necrosis factor-alpha have been implicated in the regulation of amyloid peptide protein synthesis.	15118486
Inflammation, Transtentorial hernia, Hemorrhage, Edema	Altered Intercellular Communication	Both patients declined rapidly and expired within 48 hours of admission secondary to transtentorial herniation caused by the mass effect of inflammation, edema, and hemorrhage with displacement of the brain stem.	15119487
vascular inflammations, Restenosis, Angina Pectoris	Altered Intercellular Communication	Both vascular inflammation as determined by C-reactive protein (CRP) and extrinsic coagulation as measured by factor VII activity (F VII) may predict clinical restenosis rate in patients with stable angina pectoris undergoing elective percutaneous coronary intervention (PCI).	15119695
Inflammation, Atherosclerosis	Altered Intercellular Communication	We sought to examine the interrelationship between statin use, inflammation, and outcome of high-risk patients with advanced atherosclerosis.	15120884
Pachymeningitis, Inflammation	Altered Intercellular Communication	Middle ear inflammation appeared to induce pachymeningitis and to exacerbate associated symptoms, leading to a decline in the patient's overall condition.	15121225
Inflammation, Transmissible canine venereal tumor	Altered Intercellular Communication	We speculate that removal of the infectious granulation within the middle ears and mastoids ameliorated the acute inflammation.	15121225
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	Considering the 83 paired adequate specimens, the best sensitivity of FN vs. CN was for portal inflammation (0.95%) and the worst for cirrhosis (0.33%).	15123366
Necrotizing Enterocolitis	Altered Intercellular Communication	Necrotizing enterocolitis is a devastating inflammatory condition of the intestine that occurs almost exclusively in premature newborns.	15123821
Inflammation, Acromegaly, Anterior nares, Rhinitis	Altered Intercellular Communication	Nonallergic rhinitis with eosinophilia syndrome (NARES) constitutes a rare nasal condition characterized by a chronic, eosinophilic inflammation.	15124166
Rhinitis, Vasomotor, Sinusitis, Anterior nares, Nasal Polyps, IL13 gene, Nasal inflammation	Altered Intercellular Communication	Ten patients were diagnosed to suffer from NARES (mean age 56.8 +/- 12.5, body mass index [BMI] 29.3 kg/m(2) +/- 2.8; 9 men:1 woman) and were compared with 16 age- and BMI-matched individuals (mean age 58.8 +/- 11.6, BMI 29.7 kg/m(2) +/- 3.8, 16 men) without any nasal inflammation, such as allergic rhinitis, sinusitis, nasal polyposis, or vasomotor rhinitis.	15124166
Slow shallow breathing, Nasal inflammation, Anterior nares	Altered Intercellular Communication	Patients suffering from NARES revealed significantly (P <.01) impaired polysomnographic parameters (hypopnea index, apnea-hypopnea index, mean and minimal oxygen saturation) compared with patients without any nasal inflammation.	15124166
Sleep Apnea, Obstructive, Acute and chronic inflammation	Altered Intercellular Communication	Our data support results of others, suggesting chronic nasal inflammation to cause OSAS.	15124166
PROS1 gene, Inflammation, Arthritis, Psoriatic, Spondylitis	Altered Intercellular Communication	Subclinical gut inflammation has been described in patients with ankylosing spondylitis (AS) or psoriatic arthritis (PsA).	15124251
Inflammation, Tuberculosis	Altered Intercellular Communication	Tuberculosis may present as a posterior segment inflammation.	15124529
Inflammation, Lesion of liver, Liver carcinoma, End Stage Liver Disease, Fibrosis Assessment, Liver Cirrhosis	Altered Intercellular Communication	The disease could be presented with variable hepatic lesions ranging from mild inflammation, fibrosis, cirrhosis to even end stage liver disease and hepatocellular carcinoma.	15124748
Inflammation, Injury of liver, Hepatitis, FAM126A gene	Altered Intercellular Communication	It is more likely that HCC occurs against a background of inflammation and regeneration, associated with liver injury due to chronic hepatitis.	15124749
Fibrosis Assessment	Altered Intercellular Communication	The study aimed to evaluate two significant items, we try to develop and validate a non-invasive predictive tool to assess hepatic necro-inflammation and fibrosis.	15124753
Inflammation, Fibrosis Assessment, Liver Cirrhosis	Altered Intercellular Communication	The score model was applied to our patients to assess its validity where it proved to be accurate in discriminating patients with mild inflammation and fibrosis (sensitivity 81.8%, specificity 80.5% and accuracy 80.7%) and more accurate in detecting patients with cirrhosis (specificity 96.6%, sensitivity 80% & accuracy 93.6%) but less accurate in detecting patients with moderate to severe fibrosis (specificity 66.7%, sensitivity 68.7% & accuracy 67.9%).	15124753
Inflammation, Rheumatoid Arthritis, Arthritis, Reactive	Altered Intercellular Communication	Cellular and humoral markers of systemic inflammation in acute reactive arthritis and early rheumatoid arthritis.	15124937
Inflammation, Arthritis, Reactive, Refractory anemias, Sepsis, Rheumatoid Arthritis, PHB2 gene	Altered Intercellular Communication	To compare systemic inflammation in reactive arthritis (ReA), rheumatoid arthritis (RA), and sepsis using novel markers of systemic inflammation, and to study whether they are helpful in distinguishing between ReA and RA.	15124937
Cancer-related fatigue, HPT gene, Hyperparathyroidism, Secondary, Chronic Kidney Diseases	Altered Intercellular Communication	Secondary hyperparathyroidism (secondary HPT) in patients with chronic renal failure (CRF) is characterized by parathyroid gland hyperplasia and an intrinsic defect in the recognition of parathyroid hormone (PTH) secretion.	15125031
Autoimmune Diseases, Inflammation, Atrophic, Necrosis	Altered Intercellular Communication	inflammation and chronic autoimmune disorders such as SS, so they might participate in the neuroimmunomodulation and contribute to the atrophy, apoptosis and necrosis.	15126135
Refractory anemias, Inflammation	Altered Intercellular Communication	During the 1990s there have been major changes in the treatment of RA, with more aggressive control of inflammation.	15126674
Granulomatous inflammation, Granulomatous prostatitis	Altered Intercellular Communication	Granulomatous prostatitis is characterized by a pattern of granulomatous inflammation in the prostate.	15126814
Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	Association of prostatic inflammation with down-regulation of macrophage inhibitory cytokine-1 gene in symptomatic benign prostatic hyperplasia.	15126815
Inflammation	Altered Intercellular Communication	In addition, MRI demonstrated middle ear and mastoid inflammation.	15127314
Inflammation, Traumatic injury	Altered Intercellular Communication	Interleukin (IL)-8 is a pro-inflammatory cytokine of host response to injury and inflammation.	15128054
Pancreatic stone, Autoimmune Pancreatitis, Waldenstrom Macroglobulinemia	Altered Intercellular Communication	Autoimmune pancreatitis has been characterized by irregular narrowing of the main pancreatic duct and sonolucent swelling of the parenchyma, both of which are due to lymphoplasmacytic inflammation at the active stage of the disease, and by the absence of pancreatic stone formation.	15128363
Inflammation, Adenoma of large intestine	Altered Intercellular Communication	Physical activity and reduced risk of incident sporadic colorectal adenomas: observational support for mechanisms involving energy balance and inflammation modulation.	15128611
Inflammation, Adenoma	Altered Intercellular Communication	Furthermore, the results suggest indirectly that biologic mechanisms related to inflammation may play a role in the beneficial effect of physical activity on the risk of incident adenoma.	15128611
Inflammation, Ischemic stroke	Altered Intercellular Communication	In vivo MRI of brain inflammation in human ischaemic stroke.	15128622
Inflammation, Brain Injuries, Ischemic stroke	Altered Intercellular Communication	Inflammation contributes to brain damage caused by ischaemic stroke.	15128622
Inflammation, Pathology, Cerebrovascular accident	Altered Intercellular Communication	Thus, USPIO-enhanced MRI may provide an in vivo surrogate marker of cellular inflammation in stroke and other CNS pathologies.	15128622
Ischemic stroke	Altered Intercellular Communication	Plasma precursors of brain catecholaminergic and serotonergic neurotransmitters in rehabilitation patients with ischemic stroke.	15129403
Autoimmune Diseases, Inflammation, Dermatomyositis, Childhood Type	Altered Intercellular Communication	Juvenile dermatomyositis (JDM) is a rare autoimmune disease characterized by inflammation of the muscle, connective tissue, skin, gastrointestinal tract and small nerves.	15130694
Inflammation, Chronic Obstructive Airway Disease, Bronchiectasis	Altered Intercellular Communication	Bronchiectasis, exacerbation indices, and inflammation in chronic obstructive pulmonary disease.	15130905
ARCN1 gene, Chronic Obstructive Airway Disease, Colonization, Airway structure	Altered Intercellular Communication	Relationships between high-resolution computed tomography (HRCT) findings in chronic obstructive pulmonary disease (COPD) and bacterial colonization, airway inflammation, or exacerbation indices are unknown.	15130905
Inflammation	Altered Intercellular Communication	Inflammation plays a role in the pathogenesis of athero-thrombosis.	15131088
Hypotensive, Inflammation, Pain, Postoperative	Altered Intercellular Communication	Selective vs argon laser trabeculoplasty: hypotensive efficacy, anterior chamber inflammation, and postoperative pain.	15131681
Hypotensive, Inflammation, Pain Distress Question	Altered Intercellular Communication	To compare selective laser trabeculoplasty (SLT) with conventional argon laser trabeculoplasty (ALT) in terms of hypotensive efficacy, anterior chamber inflammation, and pain reported by the patients treated.	15131681
Arteriosclerosis, Hyperhomocysteinemia, Hereditary	Altered Intercellular Communication	This interpretation suggests that homocysteine is important in the pathogenesis of arteriosclerosis in persons with hereditary, dietary, environmental, hormonal, metabolic, and other factors predisposing them to hyperhomocysteinemia.	15132238
Fibromyalgia, Refractory anemias, Rheumatoid Arthritis, Chronic pain, Spondylitis	Altered Intercellular Communication	We interviewed two groups of patients: one with a well-defined inflammatory condition (rheumatoid arthritis (RA) or ankylosing spondylitis) (n = 12) and one with non-inflammatory widespread chronic pain such as fibromyalgia (n = 14).	15132522
Pain Distress Question	Altered Intercellular Communication	For the patients with inflammatory conditions, 'to be seen' implied being seen as an individual and not as a mere diagnosis, and 'to be believed' as far as pain and suffering were concerned.	15132522
Inflammation	Altered Intercellular Communication	Non-specific inflammation in the liver was observed in pathological examination in 4 cases.	15132787
palladium	Altered Intercellular Communication	The median CSF concentration of the neurotransmitter metabolites 5-hydroxyindolacetic acid (5-HIAA) and 3-methoxy-4-hydroxyphenylethyleneglycol (MHPG) was reduced significantly (49-70%) in MSA compared to PD.	15133823
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Osteoarthritic chondrocytes (OC) produce excessive prostaglandin E2 (PGE2) and nitric oxide (NO), which function as inflammation mediators in the pathogenesis of osteoarthritis (OA).	15134143
Communicable Diseases, Senile sclerosis of aortic cusp, Inflammation	Altered Intercellular Communication	Inflammation, infection, and aortic valve sclerosis; Insights from the Olmsted County (Minnesota) population.	15136064
Communicable Diseases, Inflammation, Aortic valve disorder	Altered Intercellular Communication	Atherosclerosis-related mechanisms, including inflammation and possibly infection, are likely to be involved in the pathogenesis of calcific aortic valve disease.	15136064
Vasculitis, Coronary Artery Disease	Altered Intercellular Communication	The SAA/LDL complex reflects intravascular inflammation directly and can be a new marker more sensitive than CRP or SAA for prediction of prognosis in patients with stable coronary artery disease.	15136066
Inflammation, Observation Method - Coagulation, Diabetes Mellitus	Altered Intercellular Communication	We sought to determine whether a "package of care" of intensified multifactorial cardiovascular risk intervention could reduce indices of platelet activation, inflammation, and coagulation in diabetes and whether patients with overt CVD would derive similar benefit compared with those without.	15136493
Inflammation, Observation Method - Coagulation, Diabetes Mellitus	Altered Intercellular Communication	Intensive multifactorial risk management can reduce high levels of sCD40L but can only partially correct abnormal platelet activation, inflammation, and coagulation in diabetes, particularly in patients with overt CVD.	15136493
Inflammation, Exanthema, herpetic neuralgia, Peripheral Neuropathy	Altered Intercellular Communication	Subacute herpetic neuralgia that does not progress to PHN may reflect peripheral tissue damage and inflammation caused by a particularly severe or widespread rash.	15136679
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We performed a morphological study either semiquantitatively (fibrosis and inflammation) or quantitatively (CD3+ intraepithelial lymphocytes, M30 and TUNEL+ apoptotic cells).	15139993
Inflammation, Fibrosis Assessment, Pancreas	Altered Intercellular Communication	The main pancreatic lesions were ductal epithelial alteration, periductal inflammation and fibrosis.	15139993
Orbital Pseudotumor	Altered Intercellular Communication	Orbital pseudotumor is an inflammatory condition of one or more extraocular muscles that produces limitation of ocular motility.	15140730
Communicable Diseases, Inflammation, Guillain-Barre Syndrome, Familial	Altered Intercellular Communication	To determine the rate of histologic fetoplacental inflammation in fetuses and newborns with fatal perinatal Group B-Streptococcus (GBS) infection.	15141264
Inflammation	Altered Intercellular Communication	Histologic fetoplacental inflammation is a poor indicator of perinatal GBS infection; the sensitivity is 67% in preterm and 33% in term fetuses/newborns (overall sensitivity 59%).	15141264
Inflammation	Altered Intercellular Communication	Further examination did not give any indications for inflammation as etiological factor and showed a thickening of (apparently) the small intestine.	15141652
Orbital Pseudotumor	Altered Intercellular Communication	Aggressive treatment is imperative in order to prevent permanent structural damage to the eye resulting from this idiopathic inflammation.	15141820
Inflammation, Traumatic injury, Cardiovascular Diseases	Altered Intercellular Communication	We hypothesize that the pathophysiology of many cardiovascular diseases reflects a maladaptation of the triad of trauma response: adrenergia, inflammation, and coagulation.	15142637
Inflammation, Traumatic injury	Altered Intercellular Communication	The once-adaptive trauma response can maladaptively initiate dangerous, self-propelling cycles of adrenergia, inflammation, and coagulation.	15142637
Inflammation, Traumatic injury, Vascular Diseases, Congestive heart failure	Altered Intercellular Communication	The fluid conservation and inflammation that results from the trauma triad was clearly adaptive in our prehistoric past, but in congestive heart failure the response is maladaptive, engendering self-propelling exacerbations of pump failure and vascular disease.	15142637
Inflammation, Erectile dysfunction, Constipation, Sleeplessness, Tachycardia by ECG Finding	Altered Intercellular Communication	The loss of parasympathetic function unmasks the baseline sympathetic bias inherent in the end-organs, resulting in the familiar signs of aging including tachycardia, constipation, insomnia, erectile dysfunction, fluid retention, and systemic inflammation.	15142638
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The cellular inflammation of bronchial biopsies in chronic obstructive pulmonary diseases.	15143417
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Asthma, Peeling of skin	Altered Intercellular Communication	This study was designed to describe the cellular inflammation, thickness of basement membrane (BMT) and epithelial desquamation (ED) in bronchial biopsies from patients with chronic obstructive pulmonary disease (COPD) compared with asthma and healthy individuals.	15143417
Inflammation	Altered Intercellular Communication	This demineralisation was not related to the inflammation indices, disease duration, or to the immunological pattern.	15144125
Inflammation, Atopic keratoconjunctivitis	Altered Intercellular Communication	No apparent association between periocular and ocular microcolonization and the degree of inflammation in patients with atopic keratoconjunctivitis.	15144463
Inflammation, Atopic keratoconjunctivitis	Altered Intercellular Communication	The cause of the chronic inflammation in atopic keratoconjunctivitis (AKC), the ocular manifestation of atopic eczema/dermatitis syndrome, is largely unknown.	15144463
Airway structure, Respiratory Hypersensitivity, Airway Obstruction	Altered Intercellular Communication	Asthma is a genetically complex disease characterized by respiratory symptoms, intermittent airway obstruction and airway hyper-responsiveness due to airway inflammation and remodelling.	15144468
Inflammation, Dermatomyositis, Polymyositis	Altered Intercellular Communication	Down-regulation of the aberrant expression of the inflammation mediator high mobility group box chromosomal protein 1 in muscle tissue of patients with polymyositis and dermatomyositis treated with corticosteroids.	15146429
Inflammation, Spanish Language, Spondylarthropathies, Synovitis	Altered Intercellular Communication	Since CD163+ macrophages are selectively increased in spondylarthropathy (SpA) synovitis, we investigated the role of CD163+ macrophages in synovial inflammation.	15146432
Inflammation, Impaired, Synovitis	Altered Intercellular Communication	Increased numbers of CD163+ macrophages in SpA synovium and local production of sCD163 are associated with global inflammation as well as impairment of T cell activation, suggesting a dual role for CD163+ macrophages in SpA synovitis.	15146432
Inflammation, Helicobacter-associated gastritis	Altered Intercellular Communication	Genes involved in regulating antimicrobial immunity and inflammation may modulate the risk of Helicobacter pylori-associated diseases.	15146559
Inflammation, Congenital Abnormality, Stricture of ureter, Urologic Diseases, Urolithiasis, Kidney and Ureter Neoplasm	Altered Intercellular Communication	Of these 102 patients, 40 cases were proved to have urolithiasis, 24 cases were with renal or ureteral tumors, and there were 38 cases of other urinary system disorders (including inflammation, ureteral stricture and congenital anomalies).	15146902
ARCN1 gene, Inflammation, Respiratory Tract Infections	Altered Intercellular Communication	Markers of inflammation and oxidative stress during lower respiratory tract infections in COPD patients.	15148836
Inflammation, Infection	Altered Intercellular Communication	The aim of this study was to investigate if non- or less invasive markers of inflammation and oxidative stress can predict the course of the infections.	15148836
Suppurative inflammation, Suppurative otitis media, Acute purulent pericarditis, Pneumonia	Altered Intercellular Communication	A 50 year old man was admitted to ICU due to purulent pericarditis, purulent inflammation of the soft tissue of the neck, purulent mediastinitis and pneumonia.	15148842
Inflammation, Neoplasms	Altered Intercellular Communication	Fibromas are rare tumors of the nasal cavity, which may result from progressive inflammation or fibroblastic proliferation of the nasal mucosa.	15149003
Kidney Failure, Chronic, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic inflammation and oxidative stress are highly prevalent in patients with chronic kidney disease and end-stage renal disease (ESRD).	15149350
Uremia, Inflammation	Altered Intercellular Communication	These findings suggest that MHD is ineffective in controlling inflammation and oxidative stress in uremia.	15149350
Psoriasis	Altered Intercellular Communication	Our data suggested that psoriasis is an inflammatory condition in which neutrophils seem to play a crucial role by contributing to the development of oxidative and proteolytic stress.	15149504
Inflammation, Hypertension, CTCAE, Atherosclerosis	Altered Intercellular Communication	Chronic low-grade inflammation may contribute to the increased risk of atherosclerosis in essential hypertension.	15149889
Inflammation, Reperfusion Injury, Postoperative myocardial infarction	Altered Intercellular Communication	Inflammation and ischemia-reperfusion injury during coronary artery bypass graft (CABG) surgery requiring cardiopulmonary bypass are associated with postoperative myocardial infarction (MI) and mortality.	15150203
Inflammation, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	Malnutrition and inflammation are associated with impaired pulmonary function in patients with chronic kidney disease.	15150347
Inflammation, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation and malnutrition are common findings in patients with chronic kidney disease (CKD).	15150347
Inflammation, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	Impaired pulmonary function is associated with malnutrition and inflammation, and predicts mortality in CKD patients.	15150347
Respiratory Muscles, Inflammation, Malnutrition, Pulmonary Dysfunction	Altered Intercellular Communication	This may reflect an impact of malnutrition and inflammation on respiratory muscle performance, leading to pulmonary dysfunction, which could influence the clinical outcome.	15150347
Oropharyngeal, Inflammation, Gastrointestinal mucositis, Toxic effect	Altered Intercellular Communication	Oral mucositis (OM), the painful inflammation of oropharyngeal tissues, is an economically costly chemotherapy toxicity.	15150704
HD Term Type, Inflammation	Altered Intercellular Communication	Nevertheless, iron status estimation in HD patients remains problematic, as most parameters are influenced by inflammation.	15151266
Kidney Failure, Chronic, Inflammation, Atherosclerosis, Diabetes Mellitus, Atherogenesis	Altered Intercellular Communication	As atherogenesis is mediated by inflammation of vessel walls and as evidence evolves that atherosclerosis and diabetes mellitus share a common inflammatory basis, we considered whether ESRD patients with additional diabetes mellitus exhibit increased inflammation levels exceeding those of ESRD patients without diabetes mellitus.	15151267
Inflammation, IGA Glomerulonephritis, Red Cross, Blood capillaries	Altered Intercellular Communication	Theoretical explanations for exacerbation of IgAN to crescentic GN, following successful reperfusion, could be enhancement of capillary damage, inflammation and oxidative stress.	15151270
Inflammation, immunoglobulin A	Altered Intercellular Communication	Putative mechanisms for these phenomena may be interaction of reperfusion-induced hyperfiltration, high intraglomerular capillary pressure, oxidative stress, increased polymorphonucler cells infiltration and inflammation; the presence of IgA immune deposits and azathioprine metabolites, both can also be associated to enhancement of oxidative stress.	15151270
Inflammation, Bronchiectasis, muscle hyperplasia	Altered Intercellular Communication	This condition should be recognized as a tumor-like form of smooth muscle hyperplasia induced by bronchiectasis and inflammation.	15153164
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation is hypothesized to play a significant role in the development of type 2 diabetes; however, reports on clinical inflammatory conditions are limited.	15153457
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation is hypothesized to play a significant role in the development of type 2 diabetes; however, reports on clinical inflammatory conditions are limited.	15153457
Inflammation	Altered Intercellular Communication	Overexpression of the constitutive chemokine receptor CXCR4 has been shown to contribute to the accumulation of leukocytes at sites of chronic inflammation.	15153539
Communicable Diseases, Neoplastic disease	Altered Intercellular Communication	Despite pervasive pseudopathology, a remarkable array of diseases are well substantiated in the paleorecord, including infectious, heritable, nutritional, hormonal, acquired, iatrogenic, and neoplastic disorders.	15153895
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation is a characteristic feature of the disorder, resembling the tissue response to mycobacterium.	15154014
Inflammation	Altered Intercellular Communication	Leukocyte migration is critical to maintaining host defense, but uncontrolled cellular infiltration into tissues can lead to chronic inflammation.	15155777
HD Term Type, Peritonitis, Tuberculosis	Altered Intercellular Communication	Eleven cases of tuberculous peritonitis (TBP) in hemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD) patients at the Kaohsiung Veterans General Hospital in Kaohsiung, Taiwan between 1991 and 2000 were studied retrospectively (six cases in the HD group and five cases in the CAPD group) The diagnosis of TBP was established by either positive ascite tuberculosis (TB) culture or biopsy-proven chronic granulomatous inflammation.	15155986
Gastritis	Altered Intercellular Communication	Histology showed a H2-receptor antagonist-associated increase in the depth of gastric corpus inflammation.	15156900
Inflammation, Distortion	Altered Intercellular Communication	Distortion of iron status indices by acute inflammation in older hospitalized patients.	15158579
Acute inflammation	Altered Intercellular Communication	Thirty-nine consecutive patients (25 men and 14 women; median age 79 years) with acute inflammation episode were evaluated.	15158579
Inflammation	Altered Intercellular Communication	SF was slightly higher than normal at T-basal and increased further during inflammation (+41% at T5 versus T-basal) to reduce at T-final (-36% versus T5; P < 0.01).	15158579
Inflammation, Anemia	Altered Intercellular Communication	The indices of iron status are disrupted in elderly patients during acute inflammation, just as they are in chronic inflammation, and cannot therefore be used to diagnose sideropenic anemia.	15158579
ovarian neoplasm, Inflammation	Altered Intercellular Communication	Increased physical activity may lower the risk of ovarian cancer by reducing the frequency of ovulation, decreasing body fat, or diminishing chronic inflammation.	15159308
Neoplasms, Galactorrhea associated with childbirth	Altered Intercellular Communication	The clinical, hormonal, and radiological findings and the therapy of galactorrhea associated with granulosa cell tumor in a child are discussed.	15160508
Inflammation, Atherosclerosis, Coronary Arteriosclerosis, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cerebrovascular accident, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Three blood markers of inflammation (high-sensitivity C-reactive protein [hsCRP], interleukin [IL]-6, and fibrinogen) were compared with markers of atherosclerotic cardiovascular disease (CVD) (history of stroke or cardiac ischemia and measured toe-brachial index [TBI]) to determine whether inflammatory markers are associated with atherosclerosis in patients with type 2 diabetes.	15161792
vascular inflammations	Altered Intercellular Communication	Of these inflammatory markers, serum hsCRP may be the most promising marker for vascular inflammation.	15161792
Inflammatory abnormality of the eye	Altered Intercellular Communication	4/8 patients from Group A and 7/7 patients of Group B showed postoperatively a strong reduction of the ocular inflammation.	15162267
Macular Edema, Cystoid, Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	Ocular surgery was performed according to a standard protocol, autoimmune follow-up visits were focused on the early detection of complications of uveitis: increased ocular inflammation, synechiae, retraction of the rhexis, opacification of the posterior capsule or onset of cystoid macular edema.	15162272
Inflammation	Altered Intercellular Communication	In addition, a gallium-scan fused with a myocardial perfusion scan and cardiac magnetic resonance imaging (MRI) suggested focal inflammation near the atrioventricular (AV) node.	15163113
Disorder of vein, Hereditary	Altered Intercellular Communication	The most significant risk factors of the onset of chronic venous diseases include hereditary predisposition, pregnancy and birth, overweight, and intake of hormonal contraceptives.	15163993
Infarction, Inflammation, Myeloid Leukemia, Chronic, diabetic	Altered Intercellular Communication	With this novel monoclonal antibody against CML, the localization of CML was investigated by immunohistochemistry, in heart tissue of controls (n = 9) and heart tissue of diabetic patients (n = 8) without signs of inflammation or infarction.	15164755
Inflammation, thromboembolic, Corneal Endothelial Cell Loss	Altered Intercellular Communication	We hypothesized that indexes of inflammation (as indicated by C-reactive protein and interleukin-6) and indexes of the prothrombotic state in AF that represent platelet activation (soluble P-selectin levels), endothelial damage or dysfunction (von Willebrand factor), coagulation (tissue factor and fibrinogen), and hemorrheology (plasma viscosity and hematocrit) would be related to the presence of thromboembolic predictors on transesophageal echocardiography in patients with long-term AF.	15165916
Kidney Failure, Interstitial inflammation	Altered Intercellular Communication	Granulocyte extravasation and recruitment to sites of interstitial inflammation in patients with renal failure.	15166474
Interstitial inflammation	Altered Intercellular Communication	We have shown that leukocytes collected from sites of interstitial inflammation in patients on hemodialysis have a disturbed expression of CD11b compared to cells from healthy subjects.	15166474
Kidney Failure, Interstitial inflammation	Altered Intercellular Communication	The aim of the present study was to study adhesion molecule expression on granulocytes in the peripheral circulation and at sites of interstitial inflammation in patients with renal failure.	15166474
Interstitial inflammation	Altered Intercellular Communication	Skin chambers were applied and exposed to buffer or serum for 10 h in order to induce an intermediate and an intense interstitial inflammation.	15166474
Inflammation, Kidney Failure	Altered Intercellular Communication	At the sites of intermediate and intense inflammation, granulocytes from patients with renal failure showed significantly higher expression of CD62L (p < 0.01 and p < 0.001, respectively) and significantly lower expression of CD11b (p < 0.0001 and p < 0.0001, respectively) compared to corresponding cells from healthy subjects.	15166474
Inflammation, Kidney Failure	Altered Intercellular Communication	The interstitial concentration of IL-8 was significantly lower at the sites of intermediate (p < 0.005) and intense inflammation (p < 0.05) in patients with renal failure compared to in healthy subjects.	15166474
Kidney Failure, Interstitial inflammation	Altered Intercellular Communication	Constitutive cellular determinants are probably involved in the disturbed expression of adhesion molecules on granulocytes at sites of interstitial inflammation in patients with renal failure.	15166474
Inflammation, septic	Altered Intercellular Communication	We investigated the time course of HLA-DR expression in the early phase of AP and the relationship to markers of inflammation, severity of the disease, organ function, septic complications and outcome during AP.	15166475
Inflammation	Altered Intercellular Communication	Surgical incision and drainage yielded purulent material, granulomatous inflammation, with AFB.	15166745
Refractory anemias, Arthritis	Altered Intercellular Communication	This study demonstrates that Tc-dextran scintigraphy is a sensitive method to detect active joint inflammation and could be useful in the management of patients with RA.	15167520
Inflammation	Altered Intercellular Communication	Inflammatory mediators delay neutrophil apoptosis, which contributes to the persistence of inflammation.	15167679
Leukemic Infiltration, Orbital Pseudotumor, Exophthalmos, Glaucoma, CTCAE, Leukemia, Myelocytic, Acute	Altered Intercellular Communication	A 71-year-old man with acute myeloid leukemia presented with bilateral uveal and orbital leukemic infiltration presenting as tense bilateral proptosis, orbital inflammation, and acute-angle closure glaucoma.	15167739
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Biopsy of the inferior rectus muscle showed chronic granulomatous inflammation suggestive of foreign body reaction.	15167743
Eosinophilic disorder, Fibrosis Assessment, Interstitial inflammation, Pneumonia	Altered Intercellular Communication	Pulmonary pathology is variable, the most common being eosinophilic pneumonia with peripheral eosinophilia, and interstitial inflammation with or without fibrosis.	15168156
Inflammation, Arthropathy	Altered Intercellular Communication	Cytokines, which have been demonstrated in synovial fluids during various joint diseases, play an important role in mediating synovial inflammation and in regulating the immune response of many inflammatory processes.	15168183
Inflammation, Damage	Altered Intercellular Communication	Because the role of these cytokines is to modulate inflammation, better knowledge of the involvement of cells and their soluble mediators in articular damage could guide immunomodulating treatment.	15168183
Abscess, Inflammation, Bacterial Infections	Altered Intercellular Communication	Bacterial infections were confirmed in 5 cases (1 mucocele, 3 abscesses, 1 necrotizing inflammation).	15168225
Refractory anemias, Inflammation	Altered Intercellular Communication	High sensitivity CRP testing reveals systemic inflammation that is generally not detectable with routine CRP assays and that is associated with disease activity in RA.	15170920
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	A growing body of evidence suggests that Alzheimer's disease (AD) is associated with local inflammation processes, including the activation of inflammatory cytokines.	15172100
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	We sought to test the hypothesis that there is a relationship between inflammation and the prothrombotic state in atrial fibrillation (AF).	15172416
Inflammation, Thrombosis, Atrial Fibrillation	Altered Intercellular Communication	Inflammation may be involved in the pathogenesis of AF, but the role of inflammation in the pathophysiology of the prothrombotic state of AF has not been studied in detail, despite evidence of a link between inflammation and arterial atherothrombotic disorders.	15172416
Inflammation, Vascular Diseases	Altered Intercellular Communication	These indexes of inflammation are related to indexes of the prothrombotic state and may be related to the clinical variables of the patients (underlying vascular disease and co-morbidities), rather than simply to the presence of AF itself.	15172416
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Dissociation of lung function and airway inflammation in chronic obstructive pulmonary disease.	15172889
Airway structure, ARCN1 gene, Asthma	Altered Intercellular Communication	We conclude that airflow limitation, airway inflammation, and features commonly associated with asthma are separate and largely independent factors in the pathophysiology of COPD.	15172889
Inflammation, Hyphema, Traumatic injury	Altered Intercellular Communication	The Authors report a case of a 13-Year-old white child who presented a grade I hyphema, anterior chamber inflammation after trauma.	15173649
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Inflammation plays a key role in the development of colorectal cancers.	15173859
Airway structure, ARCN1 gene	Altered Intercellular Communication	Macrolide antibiotics have been shown to improve airway inflammation in diffuse pan-bronchiolitis but their role in COPD is undetermined.	15174894
Inflammation, Intimal proliferation, Pathology	Altered Intercellular Communication	Inflammation, which is associated both with neointimal hyperplasia and MACE, seems a common characteristic of different vascular pathologies.	15174911
Inflammation, Tachyarrhythmia, Myocardial	Altered Intercellular Communication	Markers of myocardial damage, tissue healing, and inflammation after radiofrequency catheter ablation of atrial tachyarrhythmias.	15175065
Inflammation, Myocardial Infarction, Myocytes, Cardiac	Altered Intercellular Communication	Radiofrequency ablation produces a localized endomyocardial necrosis that may result in release of biochemical markers reflecting myocardial cell damage, inflammation, and tissue reparation.	15175065
Inflammation, Myocardial	Altered Intercellular Communication	Markers of inflammation, wound healing, and myocardial damage are increased in patients who undergo radiofrequency ablation.	15175065
vascular inflammations, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Vascular inflammation plays an important role in the development of myocardial infarction (MI).	15175864
Airway structure	Altered Intercellular Communication	Measurement of exhaled NO is an easy, non-invasive procedure that can be used to monitor the level of airway inflammation.	15176292
Airway structure, ARCN1 gene	Altered Intercellular Communication	Impact of sputum bacteria on airway inflammation and health status in clinical stable COPD.	15176680
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterised by sputum production, bacterial colonisation, neutrophilic bronchial airway inflammation and poor health status.	15176680
Airway structure	Altered Intercellular Communication	Excessive salivary contamination of induced sputum samples prevents the satisfactory examination of lower airway inflammation.	15176693
Inflammation	Altered Intercellular Communication	A biopsy specimen of the stenotic area of the trachea showed a normal mucosa and non-specific chronic inflammation.	15176709
Inflammation, Thrombosis, immunoglobulin A, Hydrocephalus, Lupus Erythematosus	Altered Intercellular Communication	Histological examination demonstrated the linear deposition of IgG, IgA, IgM, C(3) and C(1q) on the dura in the absence of inflammation or thrombosis that has previously been implicated in the aetiology of elevated pressure hydrocephalus in systemic lupus erythematosus.	15177414
Inflammation, Hyperhomocysteinemia	Altered Intercellular Communication	Exhaustive search for prothrombotic factors showed inflammation, with an increased level of fibrinogen and factor IX, and a marked hyperhomocysteinemia.	15178225
Inflammation, Hyperhomocysteinemia, Crohn Disease	Altered Intercellular Communication	This observation highlights the combined proatherogenic effect of vitamin B deficiency-induced hyperhomocysteinemia and inflammation leading to large-artery stroke of the young in the setting of Crohn's disease.	15178225
Inflammation, Stomach Carcinoma, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Helicobacter pylori infection causes chronic inflammation, which can lead to gastric carcinoma.	15178435
Inflammation, Stomach Carcinoma, Infection caused by Helicobacter pylori	Altered Intercellular Communication	8-Nitroguanine could be not only a promising biomarker for inflammation but also a useful indicator of the risk of gastric cancer development in response to chronic H. pylori infection.	15178435
Cardiovascular Diseases	Altered Intercellular Communication	Incidence of obesity-associated cardiovascular disease is related to inflammation-sensitive plasma proteins: a population-based cohort study.	15178569
Inflammation	Altered Intercellular Communication	Neutrophils not stimulated by cAMP-elevating agents showed increased apoptosis when exposed to the cA-PK inhibitors Rp-8-Br-cAMPS and H-89, suggesting that even moderate activation of cA-PK is sufficient to enhance neutrophil longevity and thereby contribute to neutrophil accumulation in chronic inflammation.	15178699
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Monocyte cytokine production, systemic inflammation and cardiovascular disease in very elderly men and women: the Framingham Heart Study.	15179102
Airway structure	Altered Intercellular Communication	These results indicated that specific variants of the DAP3 gene might be associated with the mechanisms responsible for adult BA and contribute to airway inflammation and remodeling.	15179560
Refractory anemias, Inflammation	Altered Intercellular Communication	The fourth study demonstrated a highly significant association between summary measures of inflammatory variables and radiographic outcome, as defined in the second study, indicating that the degree of inflammation is important for the development of destructive joint damage in RA.	15180092
Inflammatory Bowel Diseases, Inflammation, Anemia	Altered Intercellular Communication	Anaemia associated with IBD can be successfully treated with intravenously administered iron sucrose, provided that bowel inflammation is treated adequately and enough iron is given.	15180183
allergic inflammation	Altered Intercellular Communication	An increased traffic of circulating CD34+ Hemopoietic Precursors Cells (HPC) is an important feature of systemic allergic inflammation.	15180351
Communicable Diseases, Fibrosis Assessment, Hepatitis C, Hepatitis	Altered Intercellular Communication	Racial differences in liver inflammation and fibrosis related to chronic hepatitis C. Hepatitis C virus (HCV) infection is more prevalent in black compared with white Americans.	15181613
Airway structure, ARCN1 gene	Altered Intercellular Communication	Effect of low-dose theophylline on airway inflammation in COPD.	15182277
ARCN1 gene, Inflammation	Altered Intercellular Communication	These results suggest that 4 weeks of theophylline treatment attenuates neutrophil-associated inflammation in the airways of mild to moderate COPD patients.	15182277
Acute and chronic inflammation, Neoplasms	Altered Intercellular Communication	Probe for C16 was used as the positive reference of the method, and chronic intestinal inflammation as the experiment control for detection of C3 copies in tumor cells.	15182559
Inflammatory abnormality of the eye	Altered Intercellular Communication	No recurrence of ocular inflammation was recorded in any of the patients in group A.	15183151
Inflammation	Altered Intercellular Communication	At the last follow-up visit, both eyes of each patient in group A were free of inflammation.	15183151
Conjunctivitis	Altered Intercellular Communication	Some level of conjunctival inflammation at the last follow-up visit was noted in five patients in group B (range 0-1.5, P < 0.05).	15183151
Inflammation	Altered Intercellular Communication	These data indicate that IVIg produced a faster control of the acute inflammation and that no recurrences were observed during the follow-up.	15183151
Arthritis	Altered Intercellular Communication	The data demonstrate expression of CD44v5 in osteoarthritic cartilage and synovia, probably independent of joint inflammation.	15183433
Inflammation, Chronic disease	Altered Intercellular Communication	Inflammation has been shown to be a risk factor for several chronic diseases.	15184263
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	These findings support the hypothesis that inflammation is an independent risk factor for cancer mortality.	15184263
Inflammation	Altered Intercellular Communication	Inflammation as a possible link between coronary and carotid plaque instability.	15184282
Inflammation, Acute Coronary Syndrome, Dental Plaque	Altered Intercellular Communication	Multiple complex stenoses, plaque fissures, and widespread coronary inflammation are common in acute coronary syndromes.	15184282
Inflammation	Altered Intercellular Communication	We investigated the association between coronary and carotid plaque instability and the potential common causal role of inflammation.	15184282
Inflammation, Dental Plaque	Altered Intercellular Communication	In unstable angina, plaque instability may not be confined to coronary arteries, and inflammation may be the common link with carotid plaque instability.	15184282
Inflammation, Kidney Failure, Fluid overload, Thrombocytopenia	Altered Intercellular Communication	The severity of the findings in MRI evinced mild association with clinical fluid volume overload, high blood pressure level, inflammation, thrombocytopenia and severe clinical renal insufficiency.	15185121
Inflammation	Altered Intercellular Communication	In conclusion, these data suggest that ROS generated by chronic inflammation contribute to human hepatocarcinogenesis.	15185308
Inflammation, Dental Plaque	Altered Intercellular Communication	The data was analyzed to detect plaque reduction after a one-time use (visit 2, prebrushing and postbrushing) as well as plaque and gingival inflammation reduction after 6 weeks of use.	15185803
Inflammation, Dental Plaque	Altered Intercellular Communication	The Oralgiene toothbrush removed significantly more plaque during the one-time trial and reduced significantly more gingival inflammation during the 6-week trial.	15185803
Gingivitis, Calculi	Altered Intercellular Communication	Twenty-seven GT SC, ages 3 to 12 years old and matched for age and gender with 27 non-GT SC, were examined by 2 trained investigators who recorded calculus and gingival inflammation and reconciled differences.	15185813
Inflammation, Psoriasis, Arthritis, Psoriatic, Arthropathy	Altered Intercellular Communication	These results demonstrate that AR overexpression in both the basal and suprabasal epidermis of transgenic mice induces a phenotype that mimics cutaneous psoriasis, while basal AR expression is also associated with synovial inflammation, a precursor to the psoriasis-associated arthropathy, psoriatic arthritis.	15186320
Inflammation, Malignant Lesion, Bronchiectasis	Altered Intercellular Communication	Thirty (30) of 31 malignant lesions were positive (97% sensitivity) and 12 out of 19 benign lesions were negative (63% specificity), with positive images obtained in benign processes such as inflammation/infection and bronchiectasis.	15186606
Inflammation, Acute Coronary Syndrome, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Inflammation plays an important role in atherosclerosis and the genesis of acute coronary syndromes, i.e., atheromatous plaque disruption.	15186960
Skin Basal Cell Carcinoma, Neoplasms, Osteogenesis, Nevus, Venous stasis	Altered Intercellular Communication	Cutaneous ossification may occur in association with a variety of cutaneous neoplasms and inflammatory conditions, such as pilomatricomas, basal cell carcinomas, nevi, chondroid syringomas, venous stasis, and scars.	15187328
Sepsis, Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor alpha as a central mediator of the inflammation cascade is correlated to sepsis outcome.	15187748
Degenerative polyarthritis	Altered Intercellular Communication	Increased intercellular communication through gap junctions may contribute to progression of osteoarthritis.	15187861
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Of the patients studied, 95% had osteoarthritis and 5% had inflammation.	15188102
Refractory anemias, Inflammation	Altered Intercellular Communication	We undertook this study to examine CCRL2 expression in RA, cytokine regulation of expression, and the source of a putative ligand in an attempt to determine the role of this receptor during inflammation.	15188357
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a chronic inflammatory condition characterized by a cellular influx and destruction of the joint architecture.	15188357
Inflammation, Ground-glass opacification on pulmonary HRCT, Etiology aspects, Alveolitis	Altered Intercellular Communication	Similarly, while ground-glass opacification on HRCT accurately predicted alveolitis in the middle lung fields, HRCT did not detect all sites of inflammation and did not identify infectious etiologies.	15188367
Inflammation, Pyonephrosis	Altered Intercellular Communication	We suspected that direct invasion of inflammation from the left pyonephrosis caused the splenic abscesses, as her left kidney had adhered to the spleen.	15188621
Biliary Atresia, Inflammation	Altered Intercellular Communication	Congenital biliary atresia is suspected to originate from prenatal biliary duct inflammation of unknown etiology.	15188807
Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	This finding supports the evolving concept that chronic inflammation plays a minimal role in the progression of IPF and reinforces the importance of careful consideration of the risks and benefits of such therapies prior to their institution.	15189938
Degenerative polyarthritis	Altered Intercellular Communication	We explored the linkage between nine polymorphic loci in the IL1R1 promoter, eight in the IL1A-IL1B-IL1RN gene complex, and their association with osteoarthritis (OA), a common complex disease associated with low-level inflammation.	15190266
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Among patients, 18 showed absent, 39 mild and 14 marked cardia inflammation and their H. pylori infection rates were 17, 23 and 57%, respectively (P < 0.025).	15191510
Inflammation, Carditis	Altered Intercellular Communication	pH-metry was abnormal in 15 of 18 patients with normal cardia, 33 of 39 with mild carditis and 12 of 14 with marked inflammation.	15191510
Inflammation	Altered Intercellular Communication	Marked inflammation is associated with both H. pylori and abnormal pH testing.	15191510
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	The patient remains symptom-free, and at 2-year follow-up a computed tomography scan demonstrated decreased inflammation and shrinkage of the excluded abdominal aortic aneurysm.	15192579
Inflammation, High-Grade Squamous Intraepithelial Lesions	Altered Intercellular Communication	The other cause of false positivity was superimposition of inflammation and atypical reparative change on a background of HSIL, which then suggested invasion.	15192952
Inflammation, Neoplasms, Necrosis	Altered Intercellular Communication	Preoperative FNA smears in both cases showed loose, aggregated and isolated tumor cells that were round to polygonal, with eccentrically located nuclei, against a background of inflammation and necrosis.	15192957
Inflammation	Altered Intercellular Communication	Because ectopic lymphoid tissue generated at sites of chronic inflammation is thought to be important in sustaining immunopathological processes, we have investigated whether structures resembling lymphoid follicles could be identified in the CNS of MS patients.	15193029
Inflammation, Atherosclerosis	Altered Intercellular Communication	More recently, there is mounting evidence that inflammation plays an important role in the initiation, development as well as evolution of atherosclerosis.	15193358
Inflammation, Atherosclerosis	Altered Intercellular Communication	Based on evidence and in light of the new understanding that inflammation is an intrinsic part of the process, we would like to propose a further change of nomenclature, call the disease atheroscleritis.	15193358
Inflammation, Fatty degeneration	Altered Intercellular Communication	Histologically we found focal drop-shaped fatty degenerations with signs of mild periportal chronic inflammation.	15194387
Inflammation	Altered Intercellular Communication	The changes in cell numbers could not be explained by induction of apoptosis at the site of inflammation.	15194570
Inflammation, destruction joint, Rheumatoid Arthritis	Altered Intercellular Communication	Relationship between inflammation and joint destruction in early rheumatoid arthritis: a mathematical description.	15194582
Refractory anemias, Inflammation, destruction joint, Rheumatoid Arthritis	Altered Intercellular Communication	The relationship between inflammation and joint destruction in rheumatoid arthritis (RA) has not been unequivocally characterised.	15194582
Inflammation, destruction joint	Altered Intercellular Communication	Joint destruction is the result of the cumulative burden of inflammation over time, modified by an individual factor Re that remains relatively constant over the first 2 years of observation.	15194582
Inflammation, destruction joint	Altered Intercellular Communication	The data support a mathematical model that expresses the interrelationship between inflammation and joint destruction.	15194582
Degenerative polyarthritis, Arthritis, Swollen knee region	Altered Intercellular Communication	In patients with a flare of knee OA, specifically in patients with evidence of joint inflammation documented by knee swelling, there was a significant increase in markers reflecting cartilage and synovium metabolism that could partly be prevented by high doses of ibuprofen.	15194584
Inflammation, Musculoskeletal Pain	Altered Intercellular Communication	Correlation between 18-fluorodeoxyglucose accumulation in large vessels and serological markers of inflammation in polymyalgia rheumatica: a quantitative PET study.	15194587
Inflammation, Musculoskeletal Pain	Altered Intercellular Communication	To quantify 18-fluorodeoxyglucose (FDG) accumulation in large vessels in patients with polymyalgia rheumatica by positron emission tomography (PET), and to compare these data with serological markers of inflammation.	15194587
Arteries, Inflammation	Altered Intercellular Communication	The observed FDG accumulation in the aorta and its branches and a strong correlation between tracer uptake and markers of inflammation is suggestive of large vessel arteritis.	15194587
Inflammation	Altered Intercellular Communication	Quantitative ROI analysis appears to be a sensitive tool for detecting such inflammation.	15194587
Inflammation, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	The magnetic resonance imaging (MRI) with gadolinium can be useful to visualize the localization, activity and extent of inflammation and may be a powerful noninvasive diagnostic tool in acute myocarditis.	15194984
Bile Reflux, Inflammation, Mucous Membrane	Altered Intercellular Communication	Reflux of acid and bile can cause mucosal injury and initiate chronic inflammation.	15195681
Inflammation, Necrosis	Altered Intercellular Communication	There was also a positive correlation between the scores of intralobular inflammation and necrosis and the degree of Fas antigen expression (n = 62, r = 0.522, P = 0.001).	15195900
Inflammation	Altered Intercellular Communication	It is thought to occur as a result of chronic inflammation and lymphatic stasis, but its exact aethiopathogenesis remains elusive.	15196162
Tissue damage, Inflammation, Reperfusion Injury, Cerebrovascular accident	Altered Intercellular Communication	The brain tissue damage after stroke is mediated partly by inflammation induced by ischaemia-reperfusion injury where the complement system plays a pivotal role.	15196251
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	The early rise in CRP and the following TCC increase suggest a possible role for CRP in complement activation, which may contribute to inflammation after stroke.	15196251
Inflammation	Altered Intercellular Communication	Inflammatory cytokines have been reported to be related with inflammation and expansion of jaw cysts.	15196982
Inflammation	Altered Intercellular Communication	It is considered that fibroblasts around radicular cysts may lead to high IL-6 synthesis over time in chronic inflammation.	15196982
Inflammation, Atherosclerosis	Altered Intercellular Communication	Effects of aerobic physical exercise on inflammation and atherosclerosis in men: the DNASCO Study: a six-year randomized, controlled trial.	15197018
Inflammation, Heart failure, Congestive heart failure	Altered Intercellular Communication	Advanced chronic heart failure (CHF) is associated with abnormal haemostasis and inflammation, but it is not known how these abnormalities are related, whether they are modified by oral anticoagulants (OAT), or if they persist after successful heart transplantation.	15198737
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	There were significant correlations (r = 0.414-0.595) between coagulation, fibrinolysis, endothelial dysfunction and inflammation parameters, which were lower in those patients treated with OATs.	15198737
Histoplasmosis, Cervical lymphadenitis, Abscess, Granulomatous inflammation, Fungal, Ulcer, Immunologic Deficiency Syndromes	Altered Intercellular Communication	We present a case of disseminated histoplasmosis in a 16-year-old girl with the acquired immune deficiency syndrome who presented to the Paediatric Infectious Diseases Service of the University Hospital of the West Indies, with cervical lymphadenitis progressing to ulcers and abscesses showing granulomatous inflammation likely to be of fungal aetiology.	15199726
Nephritis	Altered Intercellular Communication	[Antiischemic efficacy of perfluoroorganic compounds in patients with renal inflammation].	15199807
Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	It has been suggested that inflammation plays a key role in the development of both atherosclerosis and malnutrition (MIA), a combination of complications associated with poor outcome.	15200411
Inflammation, Necrosis	Altered Intercellular Communication	The central portion of her left breast was already rotted by extensive necrosis and inflammation.	15201521
Inflammation, Crohn Disease	Altered Intercellular Communication	The presence of neutrophils among epithelial cells is one of the major features of the inflammation in Crohn's disease, and has been used to indicate disease activity.	15201577
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Peripheral leucocyte count, C-reactive protein and the degree of mucosal inflammation, evaluated histologically, were determined.	15201577
Crohn Disease, Intestines, Inflammation	Altered Intercellular Communication	In-vitro cell culture production of GM-CSF was increased in Crohn's disease and related to inflammation, but decreased after infliximab treatment, probably because intestinal T cell GM-CSF production was reduced.	15201577
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Matrix metalloproteinases (MMPs) are capable of degrading basement membranes and are involved in the process of tissue remodelling in inflammation and liver fibrosis.	15201662
Pleurisy	Altered Intercellular Communication	Progelatinase B/matrix metalloproteinase-9 proenzyme as a marker of pleural inflammation.	15204835
Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	These results raise the possibility that HIV-related brain inflammation disturbs neuronal protein turnover through the ubiquitin-proteasome apparatus, and might increase the prevalence of age-associated neurodegenerative diseases by decreasing synaptic protein turnover through the proteasome.	15204928
Ischemia, Compression, Inflammation, Neuropathy	Altered Intercellular Communication	The neuropathies may be caused by ischemia from an unfavorable arteriovenous flow gradient, venous compression, or secondary inflammation.	15206437
Inflammation, Bronchial Hyperreactivity, Disease	Altered Intercellular Communication	Adenosine monophosphate (AMP) acts indirectly via primed airway mast cells to induce bronchial hyper-responsiveness, which in turn correlates with eosinophilic asthmatic inflammation and atopic disease expression.	15206990
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	These data show that statins can mediate modest but clinically apparent anti-inflammatory effects with modification of vascular risk factors in the context of high-grade autoimmune inflammation.	15207950
Coughing, Airway structure	Altered Intercellular Communication	Chronic cough often lasts for more than 1 year and is associated with airway inflammation.	15208586
Respiratory Failure, Respiratory Tract Infections, Congestive heart failure	Altered Intercellular Communication	The remaining charts should have been coded as respiratory failure (13.8%), congestive heart failure (11.4%), respiratory infections and inflammations (7.7%), and other diagnoses (32.5%).	15208983
Uveitis	Altered Intercellular Communication	A case of infected scleral buckle with Mycobacterium chelonae associated with chronic intraocular inflammation.	15209466
Communicable Diseases, Inflammation	Altered Intercellular Communication	To describe a unique case of chronic intraocular inflammation secondary to scleral buckle infection with Mycobacterium chelonae that was successfully treated with buckle explantation.	15209466
Retinal Detachment, Intraocular inflammation	Altered Intercellular Communication	A 59-year-old male with a history of retinal detachment repair at the age of 41 presented with chronic, recurrent intraocular inflammation responsive to topical corticosteroids.	15209466
Intraocular Infection, Intraocular inflammation, Uveitis	Altered Intercellular Communication	This case describes a new finding of chronic intraocular inflammation associated with a scleral buckle infected with M. chelonae and the successful resolution of extraocular infection and intraocular inflammation after buckle removal.	15209466
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Findings suggest that inflammation is prognostic for incident mobility limitation over 30 months, independent of cardiovascular disease events and incident severe illness.	15209648
Inflammation, Hyperalgesia, Allodynia, Pain Distress Question	Altered Intercellular Communication	Dermal inflammation from many causes may produce a reversible period of hyperalgesia (increased sensitivity to pain perception) or allodynia (pain from innocuous stimuli).	15209970
Myocarditis	Altered Intercellular Communication	Widespread myocardial inflammation and infarct-related artery patency.	15210601
Vasculitis, Acute Coronary Syndrome	Altered Intercellular Communication	Diffuse coronary vascular inflammation is associated with acute coronary syndromes.	15210601
Inflammation	Altered Intercellular Communication	However, it is unknown whether inflammation also occurs within the myocardium.	15210601
Ulcer of nose, Inflammation, Meningoencephalitis	Altered Intercellular Communication	We present a case of 23-year-old man with acute meningoencephalitis, accompanied by inflammation of a nasal ulcer.	15211011
Necrotizing granulomatous inflammation	Altered Intercellular Communication	A skin biopsy showed chronic noncaseous granulomatous inflammation without demonstrated microorganisms.	15211011
Amoeba genus, Chronic necrotizing inflammation	Altered Intercellular Communication	At autopsy, hematoxylin and eosin-stained brain sections showed a chronic necrotizing inflammation with numerous amebic trophozoites and rare cysts.	15211011
Inflammation, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	These findings suggest that obesity is associated with inflammation independent of other cardiovascular risk factors that may contribute to an increased risk for cardiovascular disease in men and women.	15211365
Dyslipidemias, Diabetes Mellitus, Hepatobiliary Disorder, Malignant Neoplasms, INTERCURRENT INFECTION	Altered Intercellular Communication	Subjects had no symptoms of intercurrent infection, known diabetes, treated dyslipidaemia, a chronic inflammatory condition, liver disease or malignancy.	15211367
Microalbuminuria, Inflammation	Altered Intercellular Communication	Microalbuminuria is associated with age, systolic blood pressure, and markers of inflammation.	15211434
Airway structure, Asthma	Altered Intercellular Communication	Childhood asthma: exhaled markers of airway inflammation, asthma control score, and lung function tests.	15211692
Airway structure, Asthma	Altered Intercellular Communication	Exhaled markers of airway inflammation become increasingly important in the management of childhood asthma.	15211692
Granulomatous inflammation, Neurologic Deficits	Altered Intercellular Communication	Despite the initial treatment with a conventional dose of itraconazole (ITCZ, 200 mg/day), the neurological deficits failed to improve and the granulomatous inflammation was not suppressed.	15212149
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inappropriate chronic inflammation associated with progressive, chronic kidney disease (CKD) reflects sustained activation of immunocompetent cells, like monocytes/macrophages.	15213278
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Posited was the notion that RAGE plays a contributory role to monocyte-mediated systemic inflammation of progressive CKD.	15213278
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Enhanced RAGE may amplify AGE-induced monocytes perturbation and contribute to monocyte-mediated systemic inflammation in progressive CKD.	15213278
Airway structure, Asthma	Altered Intercellular Communication	"Refractory" eosinophilic airway inflammation in severe asthma: effect of parenteral corticosteroids.	15215154
Airway structure, Asthma	Altered Intercellular Communication	It has been suggested that patients with refractory eosinophilic airway inflammation represent a separate "eosinophilic" asthma phenotype associated with increased morbidity and a poor prognosis.	15215154
Suprarenal, Purpura	Altered Intercellular Communication	The hypothesis of the connection between hormonal activity of the suprarenal adenoma and development of the peliosis was expressed.	15216676
Cataract, Syndrome	Altered Intercellular Communication	Local changes, like grade of cataract maturity, PEX syndrome, inflammations and structural changes of vitreous body has a crucial influence on the operation process.	15218757
Inflammation, Chronic idiopathic neutropenia, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	Patients with chronic idiopathic neutropenia (CIN) usually show chronic inflammation in their bone marrow stromal cells, but the etiologies of this disorder are still unknown.	15218961
Inflammation, Microvascular Angina, Coronary Artery Disease	Altered Intercellular Communication	Assessment of systemic inflammation and infective pathogen burden in patients with cardiac syndrome X. Inflammation plays a key role in coronary artery disease (CAD), but whether it is involved in the pathogenesis of syndrome X (SX) is not known.	15219506
Inflammation, Helicobacter pylori, Chlamydia, Infection	Altered Intercellular Communication	Thus, we assessed the presence of systemic inflammation in patients with SX and its possible relation to infections from Helicobacter pylori, Chlamydia pneumoniae, cytomegalovirus, and Epstein-Barr virus.	15219506
Inflammation, Angina Pectoris	Altered Intercellular Communication	Among patients with SX, no correlation was found between markers of inflammation and indexes of disease activity (angina episodes, exercise test results).	15219506
Inflammation, Pathogenic organism	Altered Intercellular Communication	Our data show evidence of increased low-grade systemic inflammation in patients with cardiac SX, which was unrelated to an increased infectious pathogen burden.	15219506
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The findings support the emerging hypothesis that chronic subclinical inflammation is associated with insulin resistance and comprises a component of the metabolic syndrome.	15220201
Xanthogranulomatous inflammation, Erdheim-Chester Disease, Histiocytic syndrome	Altered Intercellular Communication	Erdheim-Chester disease (ECD) is a rare histiocytosis, histologically characterized by xanthogranulomatous inflammation.	15221300
Inflammation	Altered Intercellular Communication	This was further substantiated by an orbital biopsy revealing chronic fibrosing inflammation.	15221300
Inflammation, Lupus Erythematosus	Altered Intercellular Communication	Our data suggest that fluctuations in blood dendritic cell count in systemic lupus erythematosus patients are much more significant in pDC than in mDC, what may be caused by their migration to the sites of inflammation including skin lesions.	15223608
Inflammation, Pouchitis	Altered Intercellular Communication	Positive titres of pANCAs were associated with inflammation in the neoterminal ileum; 80% of patients with high pANCA levels (>100) had pouchitis.	15223678
Inflammation, Hemorrhage, Blood Clot, Fibrosis Assessment	Altered Intercellular Communication	All cases showed some degree of hemorrhage, fibrin deposition and fibrin thrombi, fibrosis, and acute and chronic inflammation, with hemosiderin identified in 60% of cases.	15223961
Inflammation, Hemorrhage	Altered Intercellular Communication	Bleeding and inflammation are major complications of extracorporeal circulation.	15224025
Inflammation, Complication Aspects	Altered Intercellular Communication	Requirement for allogeneic transfusions, thrombotic complications, outcomes, and monitoring of coagulation, fibrinolysis, and inflammation were also recorded.	15224025
Inflammation, Hemorrhage	Altered Intercellular Communication	By affecting fibrinolysis, tranexamic acid significantly reduces bleeding both in off- and on-pump coronary artery bypass grafting and may modulate inflammation in these surgical settings.	15224025
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Thus, nonhemodynamic factors such as inflammation and altered cellular redox state may play a greater role in the generation of oxidative stress in CKD.	15224800
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	In conclusion, this study suggests that dietary (n-3) fatty acids are associated with levels of these biomarkers reflecting lower levels of inflammation and endothelial activation, which might explain in part the effect of these fatty acids in preventing cardiovascular disease.	15226473
Inflammation, Synovitis	Altered Intercellular Communication	The MRI examination included evaluation of inflammation using a synovitis score and evaluation of destruction with an erosion score.	15228185
Traumatic injury	Altered Intercellular Communication	However, in the most common age group, the older patients, there might be another (probably non-HPV-related) etiology associated with hormonal factors and trauma to the vagina.	15228423
Inflammation, Neoplasms	Altered Intercellular Communication	Inflammation and hormonal signalling induce cyclooxygenase 2 (COX2) expression in solid tumours.	15228443
Inflammation, Neoplasms	Altered Intercellular Communication	Inflammation and hormonal signalling induce cyclooxygenase 2 (COX2) expression in solid tumours.	15228443
Inflammation, Neoplasms	Altered Intercellular Communication	Inflammation and hormonal signalling induce cyclooxygenase 2 (COX2) expression in solid tumours.	15228443
Granulomatous inflammation, Colitis	Altered Intercellular Communication	Microscopic colitis rarely may be characterized by granulomatous inflammation.	15228447
Mesenteric Panniculitis, Inflammation	Altered Intercellular Communication	Mesenteric panniculitis is a rare condition of unknown etiology that causes inflammation of the adipose tissue in the mesentery.	15228879
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Effects of fluticasone on systemic markers of inflammation in chronic obstructive pulmonary disease.	15229100
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Cardiovascular morbidity	Altered Intercellular Communication	Systemic inflammation is present in chronic obstructive pulmonary disease (COPD), which has been linked to cardiovascular morbidity and mortality.	15229100
Refractory anemias, Inflammation	Altered Intercellular Communication	In RA, thrombin was found to be related to the enhanced growth of SFC and the release of IL-8 from these cells; thus thrombin is probably related to worsening of inflammation through the recruitment of leukocytes (neutrophils), which release cathepsin B into the SF.	15229942
Meningitis, Bacterial, Inflammation, UGCG gene	Altered Intercellular Communication	Assessment of patients with bacterial meningitis on the basis of GCS is helpful to establish prognosis, and CGS seems to correlate with the intensity of inflammation in the CSF.	15230146
Inflammation, Lupus Erythematosus, Systemic, Thrombosis of blood vessel, Electrocardiogram: myocardial infarction (finding), Antiphospholipid Syndrome	Altered Intercellular Communication	The authors conclude that myocardial infarction in SLE could be caused by a combination of cardiac microvascular thrombosis and inflammation accompanying the antiphospholipid syndrome.	15230234
Dysplasia	Altered Intercellular Communication	Preoperative endoscopy revealed atypia/inflammation in 15 cases and dysplasia in eight.	15230725
Airway structure, Asthma	Altered Intercellular Communication	Exhaled NO may indicate eosinophilic airway inflammation during ASA exposure in patients with ASA inducible asthma.	15230814
Inflammation, Uveitis	Altered Intercellular Communication	These symptoms contrasted with the absence of the usual signs of inflammation of the anterior segment or of the retina, which characterize true uveitis.	15232310
Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the presence of autoantibodies against intracellular components, the formation of immune complexes, and inflammation in various organs, typically the skin and kidney glomeruli.	15232734
Pneumonitis	Altered Intercellular Communication	There was no development of lung inflammation into chronic stadium.	15233025
Prehypertension	Altered Intercellular Communication	Our findings may be of clinical importance, as they suggest that prehypertension might be a pro-inflammatory condition.	15233975
Inflammatory abnormality of the eye	Altered Intercellular Communication	Bisphosphonates are associated with ocular inflammation, including the first reports of drug-related scleritis.	15234126
Inflammation	Altered Intercellular Communication	Adherence to the Mediterranean diet attenuates inflammation and coagulation process in healthy adults: The ATTICA Study.	15234425
Inflammation	Altered Intercellular Communication	Adherence to the traditional Mediterranean diet was associated with a reduction in the concentrations of inflammation and coagulation markers.	15234425
Granulomatous inflammation, Bell Palsy, Necrosis	Altered Intercellular Communication	Granulomatous inflammation and nerve necrosis in a case of apparent idiopathic vocal fold paralysis: report of a case.	15235359
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Segments of this nerve were submitted for histologic evaluation, revealing necrosis with granulomatous inflammation.	15235359
Heart Diseases, Hypertension, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	A stepwise logistic regression analysis revealed that diabetes (p<0.0001); hormonal problems (p<0.0001), consumption of animal fats (p<0.0001), risk of heart disease (p<0.0001), and BMI (p=0.0307) were all associated with hypertension.	15235700
Cholecystitis, Biliary calculi	Altered Intercellular Communication	It is concluded that spillage of gallstones at laparoscopic cholecystectomy is not as benign as previously thought and that efforts to prevent spillage should include scrupulous operative technique, especially in the presence of gallbladder inflammation, and especial care when removing the gallbladder from the abdominal cavity.	15235892
Endocrine System Diseases, Abnormal platelets	Altered Intercellular Communication	The condition has been attributed to various causes such as platelet abnormalities, hormonal disturbances, and cytokine dysfunction, but the exact underlying mechanism has been elusive.	15236803
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	However, the postoperative diagnosis on histological examination of the resected lesions was chronic inflammation and fibrosis.	15237458
Inflammation	Altered Intercellular Communication	Inflammation in ileum of CD patients caused increased frequency of perforin-expressing cells and enhanced perforin-dependent TCR-/CD3-mediated cytotoxicity.	15238086
Inflammation	Altered Intercellular Communication	Ongoing normal cytolytic processes seem to be enhanced by chronic inflammation.	15238086
Inflammation, Anemia, Kidney Failure, Chronic disease	Altered Intercellular Communication	Anemia was defined by World Health Organization criteria; causes of anemia included iron, folate, and B(12) deficiencies, renal insufficiency, anemia of chronic inflammation (ACI), formerly termed anemia of chronic disease, and unexplained anemia (UA).	15238427
Refractory anemias, Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	The aim of this study was to evaluate the roles of contrast-enhanced dynamic and static magnetic resonance imaging (MRI) and quantitative 99Tcm-labelled nanocolloid (NC) scintigraphy in detecting wrist joint inflammation in early rheumatoid arthritis (RA) patients.	15238644
Inflammation	Altered Intercellular Communication	Correlations between imaging methods of the wrist and the global measures of inflammation (laboratory and clinical examinations) were also assessed.	15238644
Inflammation	Altered Intercellular Communication	Strong correlations emerged between maximal 99Tcm-NC uptake and MRI E-rates, reflecting similar performance of the methods in detecting local synovial inflammation.	15238644
Inflammation, Hamartoma	Altered Intercellular Communication	This association supports the hypothesis that inflammation is one of the factors that induce the development of a hamartoma.	15239039
Inflammation, Fibrosis Assessment, Interstitial Fibrosis Assessment	Altered Intercellular Communication	The postmortem examination revealed non-obstructive hypertrophy with irregular arrangement of muscular fibers, dilatation of the ventricles, endocardial fibrosis, microfocal vacuolization with enlarged hyperchromatic nuclei, and signs of inflammation with interstitial fibrosis.	15239350
Deafness, Sudden, Inflammation, Neurologic Symptoms	Altered Intercellular Communication	Sudden deafness without associated neurological symptoms and signs is typically attributed to a viral inflammation of the labyrinth.	15240204
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Is inflammation a consequence or a cause of atrial fibrillation?	15240964
Inflammation	Altered Intercellular Communication	These results suggest that inflammation is a causative agent of paroxymal AF.	15240964
Cessation of life, Inflammation	Altered Intercellular Communication	The resolution of neutrophil (PMN)-mediated inflammation occurs through the apoptosis, or programmed cell death, of the neutrophil.	15241089
Communicable Diseases, Inflammation	Altered Intercellular Communication	Streptavidin accumulates at sites of inflammation and infection as a result of increased capillary permeability.	15241627
Inflammation, Carcinogenesis, Dysplasia, Metaplasia	Altered Intercellular Communication	As carcinogenesis complicating chronic inflammation proceeds through the stages of dysplasia and metaplasia, mutation in the K-ras gene may be an important marker for GBC.	15242496
Inflammation, Gallbladder Carcinoma	Altered Intercellular Communication	The presence of this mutation suggests that chronic inflammation may play an etiologic role in gallbladder carcinogenesis.	15242496
Granulomatous inflammation	Altered Intercellular Communication	The lymphocytes were a minor component of the granulomatous inflammation and were predominantly CD8(+) T-cells.	15243522
Postcardiac injury syndrome	Altered Intercellular Communication	Postcardiac injury syndrome is a rare complication of radiofrequency ablation that is characterized by signs of pericardial, pleural and pulmonary parenchymal inflammation.	15243769
Inflammation	Altered Intercellular Communication	Leukocytes play a key role in inflammation, and an increase in white blood cell (WBC) counts is a nonspecific marker of inflammation.	15246898
Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Cytokine gene polymorphisms influence mucosal cytokine expression, gastric inflammation, and host specific colonisation during Helicobacter pylori infection.	15247172
Inflammation	Altered Intercellular Communication	Proinflammatory IL-1 polymorphisms (IL-1RN*2(+)/IL-1B-511T/-31C(+)) were associated with increased IL-1beta expression, more severe degrees of inflammation, and an increased prevalence of IM and AG.	15247172
precancerous lesions, Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Cytokine gene polymorphisms influence mucosal cytokine expression, gastric inflammation, and the long term development of precancerous lesions in H pylori infection.	15247172
Inflammation, Thrombosis	Altered Intercellular Communication	Erythropoietin-induced thrombosis as a result of increased inflammation and thrombin activatable fibrinolytic inhibitor.	15247979
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Chronic inflammation is a major cause of morbidity and mortality in end-stage renal disease.	15247979
Kidney Failure, Chronic, Inflammation, Thrombosis, Thrombolytic Therapy	Altered Intercellular Communication	We hypothesize that thrombosis in patients with end-stage renal disease due to increased expression of C-reactive protein (CRP) as a result of chronic inflammation promotes the release of thrombin activatable fibrinolytic inhibitor causing fibrinolytic deficit and eventually thrombosis.	15247979
Inflammation, Thrombosis, Corneal Endothelial Cell Loss	Altered Intercellular Communication	Furthermore, because endothelial nitric oxide is responsible for the maintenance of the normal vascular function, the decreased levels of nitric oxide in chronic inflammation cause endothelial damage and result in thrombosis.	15247979
Refractory anemias, Inflammation, bone destruction, Rheumatoid Arthritis	Altered Intercellular Communication	To compare ultrasonography (US) with magnetic resonance imaging (MRI), conventional radiography, and clinical examination in the evaluation of bone destruction and signs of inflammation in the metatarsophalangeal (MTP) joints of patients with rheumatoid arthritis (RA).	15248207
Refractory anemias, Arthritis, MTTP wt Allele, bone destruction	Altered Intercellular Communication	Two hundred MTP joints of 40 patients with RA and 100 MTP joints of 20 healthy control subjects were assessed with B-mode US, contrast-enhanced MRI, conventional radiography, and clinical examination for signs of bone destruction and joint inflammation.	15248207
Inflammation	Altered Intercellular Communication	Evaluation by US indicated signs of inflammation in 36 patients, while MRI and clinical examination revealed signs of inflammation in 31 patients and 20 patients, respectively.	15248207
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	To determine the signal transduction pathways in CD14+ synovial cells from patients with rheumatoid arthritis (RA) after CD40 ligation, and to examine their role in amplifying synovial inflammation in affected joints.	15248214
Refractory anemias, Inflammation	Altered Intercellular Communication	Inhibition of the CD40-CD154 interaction or its signal transduction pathways would be a strong and efficient strategy for the management of synovial inflammation in RA.	15248214
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Eighty percent of the cases had histological steatosis with a mild degree of inflammation and fibrosis.	15248380
Inflammation, Fibrosis Assessment, Fatty degeneration, Lesion of liver	Altered Intercellular Communication	Even if at univariate analysis, age, ferritin and tissue 4-hydroxynonenal were independent factors of steatosis (P < 0.01), and insulin, HOMA and ferritin of inflammation and fibrosis (P < 0.01), at multivariate analysis no single factor was found to be an independent predictor of hepatic lesions.	15248380
Nasal inflammation, Allergic Conjunctivitis	Altered Intercellular Communication	Effect of anti-immunoglobulin E on nasal inflammation in patients with seasonal allergic rhinoconjunctivitis.	15248853
Pain Distress Question, Inflammation	Altered Intercellular Communication	In a subgroup of patients with chronic mechanical knee pain without signs of inflammation (n = 123), the mean change in pain intensity from baseline was 25.2 mm v 15.2 mm, in the paracetamol (n = 63) and placebo (n = 60) groups, respectively-mean difference 10.0 mm; 95% CI 1.0 to 19.0; p = 0.0294.	15249319
Submandibular	Altered Intercellular Communication	This non-inflammatory condition is described to affect major salivary glands, leading to the characteristic parotid and/or submandibular swelling.	15250838
Addison Disease, Hypogonadism, Hypothyroidism	Altered Intercellular Communication	Hormonal evaluation revealed evidence of hypocortisolism, hypothyroidism, and hypogonadism.	15251832
Abscess of pituitary, Endocrine System Diseases, Headache, Scotoma	Altered Intercellular Communication	Bacterial pituitary abscess is rare but manifests similar to other pituitary masses with headaches, visual field defects, and hormonal disturbances.	15251832
Necrotizing granulomatous inflammation, Necrosis	Altered Intercellular Communication	Examination of the pathology specimen showed caseous granulomatous inflammation and necrosis, and acid-fast bacilli were identified.	15251839
Communicable Diseases, Inflammation, Exacerbation	Altered Intercellular Communication	Thus, we suggest that the use of clarithromycin in COPD exacerbations may either treat the infection or help control the inflammation.	15252191
Pain Distress Question, Fibromyalgia, Inflammation	Altered Intercellular Communication	The monocyte PBRs overincrease in fibromyalgia may be due to abnormalities in the regulation of pain or to inflammation.	15252208
Pouchitis, Ulcerative Colitis	Altered Intercellular Communication	Inflammation of ileal reservoir mucosa ("pouchitis") is a common sequelae in ulcerative colitis (UC) patients who have had a colectomy with ileal pouch anal-anastomosis (IPAA).	15252305
Acute inflammation	Altered Intercellular Communication	Because two similar transscleral cyclophotocoagulation diode lasers with identical power & duration settings induced significantly different postoperative inflammation, we wanted to compare the real output of both lasers.	15253487
Inflammation, Metabolic Syndrome X, Coronary heart disease	Altered Intercellular Communication	Low-grade inflammation may play a role in the etiology of the metabolic syndrome in patients with coronary heart disease: the HIFMECH study.	15254876
Inflammation	Altered Intercellular Communication	Variables attributed to insulin resistance are associated with low-grade inflammation.	15254876
Obesity	Altered Intercellular Communication	The "Metabolic Syndrome" factor was related to the "Inflammation" factor (largely independently of obesity), the "Blood Pressure" factor, smoking, and south location (all P < or = .0002).	15254876
Inflammation, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Markers of low-grade inflammation are strongly related to metabolic syndrome variables independently of obesity.	15254876
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	This raises the possibility that links between insulin resistance and cardiovascular disease could, in part, represent common consequences of low-grade inflammation.	15254876
Inflammation, Chronic disease	Altered Intercellular Communication	Discrimination ratio analysis of inflammatory markers: implications for the study of inflammation in chronic disease.	15254884
Inflammation, Chronic disease	Altered Intercellular Communication	To understand the role of inflammation in chronic disease it is important to have a reliable measure of habitual inflammatory status.	15254884
Inflammation, Chronic disease	Altered Intercellular Communication	This study suggests that use of some inflammatory markers, such as CRP, with large within-individual variability, will underestimate the relationship between inflammation and disease, and thus relationships between inflammation and chronic disease may be stronger than previously appreciated.	15254884
Tissue damage, Inflammation	Altered Intercellular Communication	Myeloperoxidase, a heme protein expressed by professional phagocytic cells, generates an array of oxidants which are proposed to contribute to tissue damage during inflammation.	15255951
Multiple Pregnancy, Hypercalcemia, CTCAE	Altered Intercellular Communication	Recurrent hypercalcemia due to ectopic production of parathyroid hormone-related protein and intact parathyroid hormone in a single patient with multiple malignancies.	15256329
Inflammation, Destruction of tissue	Altered Intercellular Communication	Examination of tissue sections revealed a carpet of pigmented fungal filaments on the corneal surface (n = 12, 92.3%) associated with mild to moderate inflammation (n = 11, 84.7%) and tissue destruction.	15256995
Inflammation, Corneal Stroma, Fungal keratitis	Altered Intercellular Communication	The pigmented plaque-like infiltrate in dematiaceous fungal keratitis consists of surface colonization of pigmented fungal filaments associated with mild to moderate inflammation and tissue destruction of the underlying corneal stroma.	15256995
Inflammatory abnormality of the eye	Altered Intercellular Communication	In all cases, ocular inflammation subsided within 2-5 weeks.	15256996
Shock, Inflammation, Neurologic Dysfunction	Altered Intercellular Communication	Patients who died of early refractory shock had lower baseline cortisol levels than patients who died of neurologic dysfunction (27 microg/dL [15-47] vs. 52 microg/dL [28-73], respectively; P < 0.01), suggesting an inadequate adrenal response to severe systemic inflammation.	15257083
Autoimmune Pancreatitis	Altered Intercellular Communication	Autoimmune pancreatitis associated with immune-mediated inflammation of the papilla of Vater: report on two cases.	15257109
AURKAIP1 gene	Altered Intercellular Communication	We report 2 cases, a 56-year-old man and a 29-year-old woman, with AIP associated with immune-mediated inflammation of the main duodenal papilla (MDP).	15257109
AURKAIP1 gene, Inflammation	Altered Intercellular Communication	Immune-mediated inflammation of the MDP may be associated with AIP.	15257109
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Carotid Intima-Media Thickness	Altered Intercellular Communication	Low-grade inflammation, endothelial activation and carotid intima-media thickness in type 2 diabetes.	15257724
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	The objective of this study was to assess the relationship between inflammation, endothelial activation and incipient atherosclerosis in type 2 diabetes.	15257724
Inflammation, diabetic	Altered Intercellular Communication	Low-grade inflammation and endothelial activation are increased in diabetic patients but do not associate with IMT or clinical CVD.	15257724
Inflammation, Granulation finding	Altered Intercellular Communication	Patients with inflammation, granulation, hordeolum, chalazion and orbital or conjunctival extension were excluded.	15258418
Parasite Present, Inflammation, SLC12A3 gene	Altered Intercellular Communication	The variability found in the number, stage, localization and inflammation in the parasite lesions is strongly associated with the heterogeneity of NCC symptoms.	15258785
Inflammation	Altered Intercellular Communication	The increased number of vesicular cysticerci and the decreased number of degenerating cysticerci with aging, as well as the prominence of inflammation in women suggest that immuno-endocrinological factors may play a role in susceptibility and pathogenesis.	15258785
neutrophilic, Inflammation	Altered Intercellular Communication	H pylori infection induces active inflammation with neutrophilic infiltrations as well as production of oxygen free radicals that can cause DNA damage.	15259072
Inflammation	Altered Intercellular Communication	These results suggest that each phospholipase A2 enzyme has distinct roles in both healthy and diseased joint tissue, and that the diversity and amount of enzyme correlate with the grade of inflammation and disease severity.	15259375
Heart failure	Altered Intercellular Communication	The concentrations of all CNHs and neurohormones were higher in patients with heart failure compared to normal subjects, except for free triiodothyronine (FT3), which was below normal values.	15259379
Acute and chronic inflammation	Altered Intercellular Communication	However, bacterial wall products such as BLP modify neutrophil tissue-destruction mechanisms and might be pivotal for perpetuation of chronic colonic inflammation.	15259513
Inflammation, Metabolic Syndrome X, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, ETV3 wt Allele	Altered Intercellular Communication	Inflammation (assessed by C-reactive protein [CRP]) and the metabolic syndrome (MetS) are associated with cardiovascular disease (CVD), but population-based data are limited.	15262834
Tumor necrosis, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	Tumor necrosis factor-alpha (TNF-alpha) one of the cytokines secreted by macrophages in response to inflammation and is also related to cancer formation.	15263792
Communicable Diseases, Inflammation, Traumatic injury	Altered Intercellular Communication	Extravasation of calcium gluconate is not an uncommon complication in neonatal units, which may result in skin and soft tissue inflammation, injury and even infection.	15264704
Osteomyelitis, Inflammation	Altered Intercellular Communication	We conclude that osteomyelitis should be considered in a patient with calcium extravasation whose soft tissue inflammation does not improve as expected.	15264704
Inflammation, Hemolysis (lab result)	Altered Intercellular Communication	The hemolytic events are often associated with an inflammatory response that usually turns into chronic inflammation.	15265937
Inflammation, Hemolysis (lab result)	Altered Intercellular Communication	Our data suggest that free heme associated with hemolytic episodes might play an important role in the development of chronic inflammation by interfering with the longevity of neutrophils.	15265937
eosinophil, Asthma, allergic inflammation	Altered Intercellular Communication	This research will help in furthering our understanding of eosinophil apoptosis and therefore might contribute to the development of better therapeutic modalities in the treatment and/or cure of allergic inflammation in bronchial asthma.	15265955
Conjunctivitis, Pyogenic granuloma, Edema, Hyperemia	Altered Intercellular Communication	The most common signs were conjunctival inflammation (edema, hyperemia), discharge, and recurrent pyogenic granuloma.	15266142
Inflammation, Necrosis, Specimen Source Codes - Abscess	Altered Intercellular Communication	Histopathologic assessment of the 15 explanted implants showed acute inflammation and necrosis (abscess) with identification of microorganisms (5 patients), acute inflammation and necrosis without identification of microorganisms (4 patients), chronic inflammation with identification of microorganisms (1 patient), chronic inflammation without identification of microorganisms (3 patients), and a predominant foreign body granulomatous response without identification of microorganisms (2 patients).	15266142
orbital pain, Chief complaint (finding), Conjunctivitis	Altered Intercellular Communication	If orbital pain (not necessarily related to implant palpation) is the main complaint, without signs of conjunctival inflammation and with or without discharge, one should consider other reasons for the symptoms.	15266142
Inflammation, Hepatitis C	Altered Intercellular Communication	The genotype mismatch (genotype 1 to genotype 2) and change to tacrolimus-based immunosuppression resulted in severe hepatitis C infection characterized by a 10-fold increase in transaminase levels and grade 3 inflammation histologically.	15268744
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	We hypothesized that patients with coronary artery disease (CAD) have increased levels of CD14+CD16+ monocytes, and that CD14+CD16+ monocytes are associated with inflammation markers.	15269840
Inflammation	Altered Intercellular Communication	The main efficacy parameters were based on 6-point ordinal scales describing the disease's signs and symptoms (scaling, inflammation and itching), global status of disease, and global change in disease.	15271194
Inflammation, Seborrheic dermatitis	Altered Intercellular Communication	The main efficacy parameters were based on 6-point ordinal scales describing the disease's signs and symptoms (scaling, inflammation and itching), global status of seborrheic dermatitis, and global change of seborrheic dermatitis.	15271195
Inflammation, Damage, Rheumatoid Factor, Rheumatoid Arthritis	Altered Intercellular Communication	Adjustment for inflammation markers, joint damage, rheumatoid factor, and glucocorticoid use reduced rheumatoid arthritis v control differences.	15271772
Inflammation, error	Altered Intercellular Communication	Association of fear of terror with low-grade inflammation among apparently healthy employed adults.	15272092
Inflammation, error	Altered Intercellular Communication	Based on evidence that psychological stress may induce a chronic inflammatory process, we hypothesized that the stress caused by chronic fear of terror may be associated with low-grade inflammation.	15272092
Inflammation, error, Cardiovascular Diseases	Altered Intercellular Communication	Chronic fear of terror in women, but not in men, is associated with elevated CRP levels, which suggests the presence of low-grade inflammation and a potential risk of cardiovascular disease.	15272092
Inflammation	Altered Intercellular Communication	[Magnetic resonance findings in a case of Gradenigo syndrome: widespread inflammation involving the paranasal sinuses and middle ear].	15272619
Inflammation, Hypothyroidism, Cardiovascular Diseases	Altered Intercellular Communication	Subclinical hypothyroidism is associated with a low-grade inflammation, increased triglyceride levels and predicts cardiovascular disease in males below 50 years.	15272919
Inflammation, Hypothyroidism, Cardiovascular Diseases	Altered Intercellular Communication	Our study demonstrates that patients with subclinical hypothyroidism have increased levels of triglycerides and signs of low-grade inflammation (raised C-reactive protein levels) and that subclinical hypothyroidism might be a risk factor for development of cardiovascular disease in younger males.	15272919
Airway structure	Altered Intercellular Communication	We showed that a moderate dose of inhaled FDP reduces levels of Fe(NO), a potential marker of airway inflammation, even in the absence of significant changes in lung function and symptoms.	15274106
Tumor necrosis, Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The increase thrombin generation rate and the correlation of plasma fragment 1 + 2 and tumour necrosis factor-alpha levels in H. pylori-positive patients suggest a role for inflammation in mediating the relationship between H. pylori infection and activation of the clotting system.	15274665
Inflammation, Crohn Disease	Altered Intercellular Communication	Chronic inflammation seen in patients with Crohn's disease leads to enhanced adhesion molecule expression in fibroblasts.	15275879
Crohn Disease	Altered Intercellular Communication	Specific inhibition of inflammatory signaling pathways could provide novel therapeutic targets for treatment of Crohn's disease.	15275879
Microalbuminuria, Inflammation, Endothelial dysfunction, Cardiovascular Diseases	Altered Intercellular Communication	Endothelial dysfunction and systemic inflammation have been proposed as common links between microalbuminuria and cardiovascular disease.	15276091
Microalbuminuria, Inflammation	Altered Intercellular Communication	We conclude that in DM the presence of microalbuminuria is associated with impaired endothelium-dependent and endothelium-independent vasodilations of the brachial artery and a higher degree of systemic inflammation.	15276091
Inflammation, Atheroma, Disease susceptibility	Altered Intercellular Communication	Findings may be attributable to APOE-related differences in inflammation, susceptibility to atheroma detachment (eg, during operative aortic manipulation), or renal vulnerability to embolic injury.	15276511
Inflammation, Anemia	Altered Intercellular Communication	Appetite and inflammation, nutrition, anemia, and clinical outcome in hemodialysis patients.	15277149
Anorexia	Altered Intercellular Communication	Malnutrition-inflammation complex syndrome, an outcome predictor in maintenance hemodialysis (MHD) patients, may be related to anorexia.	15277149
Inflammation, Thrombus, Hostility, Cardiovascular Diseases	Altered Intercellular Communication	Thus we evaluated the association between hostility and inflammation (thrombotic marker) in a population-based sample of males and females with no clinical evidence of cardiovascular disease.	15277995
Appendix Epiploica	Altered Intercellular Communication	Primary epiploic appendagitis can clinically mimic other, more serious inflammatory conditions.	15278705
Hyperplasia	Altered Intercellular Communication	The pathogenesis of this lesion is attributed to hyperplasia of stromal myofibroblasts in response to hormonal stimuli.	15279183
Kearns-Sayre syndrome	Altered Intercellular Communication	[Kearns-Sayre syndrome associated with growth hormone deficiency].	15279371
Inflammation, Malnutrition	Altered Intercellular Communication	IMT progression is associated with inflammation and malnutrition.	15280523
Inflammation, Dyslipidemias, Vascular Diseases	Altered Intercellular Communication	Dyslipidaemia, inflammation and oxidative stress are prominent risk factors that potentially cause vascular disease in haemodialysis patients.	15280524
Inflammation, Tissue Adhesions, effusion	Altered Intercellular Communication	Inflammation, effusion, and adhesions were present in the middle ear space.	15280721
Inflammation, Interstitial granulomatous dermatitis with arthritis	Altered Intercellular Communication	Interstitial granulomatous dermatitis is a histologic pattern of inflammation that generates a broad differential diagnosis.	15280826
Granulomatous inflammation	Altered Intercellular Communication	Two broad patterns of granulomatous inflammation reflecting the spectrum of changes in the course of the disease were seen.	15282726
Inflammation, Infection	Altered Intercellular Communication	Emphysema is generally the result of a chronic and progressive destruction of the alveolar structures, which is believed to be driven by chronic inflammation, infections, oxidative stress, and an imbalance of protease and antiprotease activity.	15284076
Inflammation	Altered Intercellular Communication	We report that severely emphysematous tissue is characterized by a global decrease in gene expression and by an increased abundance of transcripts encoding proteins involved in inflammation, immune responses, and proteolysis.	15284076
Inflammation	Altered Intercellular Communication	CXCL13 has also been detected in chronic inflammation associated with human lymphoid neogenesis, suggesting a pathogenic role.	15284119
Inflammation	Altered Intercellular Communication	Circulating monocytes are therefore potential candidates for future targeted therapy of chronic inflammation.	15284119
Inflammation, Cardiac Hypertrophy, Cardiovascular system	Altered Intercellular Communication	Inflammation, residual kidney function, and cardiac hypertrophy are interrelated and combine adversely to enhance mortality and cardiovascular death risk of peritoneal dialysis patients.	15284304
Inflammation, Cardiac Hypertrophy	Altered Intercellular Communication	C-reactive protein (CRP), the prototype marker of inflammation, and cardiac hypertrophy are important prognostic indicators in dialysis patients.	15284304
palladium, Inflammation, Left Ventricular Hypertrophy, Ventricular hypertrophy	Altered Intercellular Communication	This study examined the relations between inflammation, RRF, and left ventricular hypertrophy (LVH) and determined whether inflammation, RRF, and LVH combine adversely to predict the outcomes of PD patients.	15284304
palladium, Inflammation, Left Ventricular Hypertrophy, Cardiovascular system	Altered Intercellular Communication	In conclusion, inflammation, RRF, and LVH are interrelated and combine adversely to increase mortality and cardiovascular death risk of PD patients.	15284304
Inflammation, ARIH1 wt Allele	Altered Intercellular Communication	At baseline, 33% of infants had iron deficiency, and those with inflammation had lower retinol, beta-carotene, higher concentrations of copper and higher rates of ARI compared with controls.	15284376
Granulomatous inflammation	Altered Intercellular Communication	Biopsy of the nodules confirmed the destruction of hair follicles surrounded by granulomatous inflammation histologically.	15284831
Senile Plaques, Inflammation, Data types - Address	Altered Intercellular Communication	C-reactive protein (CRP) is a key molecule of the acute phase of inflammation that has been localized in the two characteristic lesions of AD brain, senile plaque and neurofibrillary tangles.	15286457
Inflammation, Orbital Cellulitis	Altered Intercellular Communication	Orbital cellulitis is an inflammation of fat and intraorbital structures that needs aggressive treatment in order to prevent serious complications.	15286906
Benign Prostatic Hyperplasia, Inflammation	Altered Intercellular Communication	Chronic inflammation in benign prostate hyperplasia is associated with focal upregulation of cyclooxygenase-2, Bcl-2, and cell proliferation in the glandular epithelium.	15287094
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Chronic inflammation has been suggested to be linked to the development and progression of prostate cancer.	15287094
Inflammation	Altered Intercellular Communication	The biopsied lung specimen by video-assisted thoracoscopic surgery showed granulomatous inflammation consisting of eosinophils and giant cells.	15287480
Inflammation, Peritonitis	Altered Intercellular Communication	The conversion rate was 9.7%, due to severe peritonitis, high-grade inflammation and an unfavorable position of the appendix; we found a significantly higher percentage of difficulty due to these factors in the laparotomic procedures.	15287639
Inflammation, Hemochromatosis, Fibrosis Assessment	Altered Intercellular Communication	Common heterozygous hemochromatosis gene mutations are risk factors for inflammation and fibrosis in chronic hepatitis C. Chronic hepatitis C is frequently associated with increased hepatic iron stores.	15287851
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	Therefore our aim was to assess associations between HFE mutations and hepatic inflammation and stage of fibrosis in German hepatitis C patients.	15287851
Inflammation, Hemochromatosis, Fibrosis Assessment	Altered Intercellular Communication	Common heterozygous hemochromatosis mutations are associated with higher grades of inflammation and more severe hepatic fibrosis.	15287851
Inflammation, Osteoporosis	Altered Intercellular Communication	Maldaptation of the link between inflammation and bone turnover may be a key determinant of osteoporosis.	15288383
Inflammation, Osteoporosis	Altered Intercellular Communication	We hypothesize that many cases of osteoporosis are also partially attributable to a maladaptation of the link between inflammation and bone turnover.	15288383
Inflammation, Reflex Sympathetic Dystrophy, Osteoporosis	Altered Intercellular Communication	We explore the spatial and temporal link between inflammation and osteoporosis in conditions such as aging, menopause, reflex sympathetic dystrophy, HIV, pregnancy, transplantation, and steroid administration.	15288383
Inflammation, Osteoporosis	Altered Intercellular Communication	While nutritional and mechanical factors clearly play a role in many of these situations, the spatial and temporal concordance of osteoporosis and inflammation is buttressed by emerging molecular evidence.	15288383
Inflammation, Osteoporosis	Altered Intercellular Communication	Osteoporosis may result from disequilibrium between structural demand for key minerals and their biologic demand during maladaptive states of inflammation.	15288383
Inflammation, Data types - Address	Altered Intercellular Communication	Given the potential importance of CCR5 in brain inflammation, we hypothesized that individuals carrying the CCR5-Delta32 allele would show a reduced risk of AD.	15288441
Inflammation, Primary malignant neoplasm, Cholangiocarcinoma, Ulcerative Colitis, Fibrosis Assessment	Altered Intercellular Communication	Due to association with inflammation, fibrosis, and cancer development, the matrix metalloproteinases MMP-1 and MMP-3 are candidate genes for predisposition to both PSC, UC and cholangiocarcinoma.	15288468
Inflammation	Altered Intercellular Communication	In patients with AH, we determined the prognostic value of TNF alpha, sTNF-R1, and lipopolysaccharide binding protein (LBP) and CD14, both involved in endotoxemia-associated inflammation.	15288471
Inflammation, Arthritis, Infectious	Altered Intercellular Communication	The joint fluid was purulent, with no crystals, and laboratory tests showed marked inflammation, leading to antibiotic treatment for suspected septic arthritis.	15288866
Conjunctivitis	Altered Intercellular Communication	Bilateral corneal and conjunctival inflammation and scarring mimicking ocular-cicatricial pemphigoid were noted.	15288986
Inflammation	Altered Intercellular Communication	Bacterial superantigens may exacerbate inflammation through activation of T-cells and subsequent cytokine release.	15289728
Inflammation	Altered Intercellular Communication	Assuming that desquamation of epithelial and inflammatory cells increases in damaged colonic mucosa, we hypothesized that fecal excretion of human DNA is an index of mucosal inflammation and damage.	15290661
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The clinical significance of right-sided colonic inflammation in patients with left-sided chronic ulcerative colitis.	15290914
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Rarely, patchy right colonic inflammation has been observed in patients with left sided chronic ulcerative colitis (CUC), but the clinical significance of this finding is unknown.	15290914
Inflammatory abnormality of the eye, Respiratory tract chondritis, Inflammatory disorder of cartilage, Nasal chondritis, Inflammatory polyarthritis	Altered Intercellular Communication	The diagnosis is dependent on clinical criteria, which include chondritis of both auricles, non-erosive inflammatory polyarthritis, nasal chondritis, ocular inflammation, respiratory tract chondritis and cochlear and/or vestibular damage.	15291945
Inflammation	Altered Intercellular Communication	In conclusion, PDS with an intravenous ultrasound contrast agent has been shown to be able to detect changes in synovial perfusion after intra-articular steroid injection and may be an additional useful method in the evaluation of synovial inflammation and in the assessment of the therapeutic response.	15293087
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Thirty-eight patients had the implant in place with no sign of inflammation or mobility, 1 patient with diabetes had inflammation around one of the struts.	15295323
Inflammation, Perforation (observation), Keratitis, Corneal Ulcer, Keratitis, Herpetic, Acute inflammation	Altered Intercellular Communication	Initial indications for grafting were nonperforated descemetocele without inflammation (six eyes, 16.2%); nonperforated bacterial corneal ulcer (five eyes, 13.5%); nonperforated herpetic keratitis with active stromal inflammation (two eyes, 5.4%); acanthamoeba keratitis (one eye, 2.7%); perforation due to herpetic keratitis (13 eyes, 35.2%); perforation due to persistent epithelial defect (8 eyes, 21.6%); or perforation due to bacterial corneal ulcer (two eyes; 5.4%).	15295664
Syphilitic, Inflammation	Altered Intercellular Communication	Postoperative inflammation was not more severe in our patients with syphilitic IK compared to patients undergoing PKP for other reasons.	15295938
Inflammation	Altered Intercellular Communication	A normal decline in ECD proved that there was no subclinical inflammation as well.	15295938
Pneumonitis	Altered Intercellular Communication	Exhaled nitric oxide (NO) increases in inflammatory lung conditions and has been proposed as a marker of pulmonary inflammation during CPB.	15296886
Pneumonitis	Altered Intercellular Communication	Leucodepletion reduces the numbers of circulating activated leucocytes and the pulmonary inflammation during CPB.	15296886
Inflammation, Fibrosis Assessment, atherosclerotic	Altered Intercellular Communication	Recent studies in apolipoprotein E-deficient mice have demonstrated a pivotal role of TGF-beta in the maintenance of the balance between inflammation and fibrosis in atherosclerotic plaques.	15297631
Inflammation, Hypersensitivity	Altered Intercellular Communication	Patients with subjective food hypersensitivity: the value of analyzing intestinal permeability and inflammation markers in gut lavage fluid.	15297775
Inflammation, Carotid artery calcification	Altered Intercellular Communication	Degree of carotid plaque calcification in relation to symptomatic outcome and plaque inflammation.	15297819
Inflammation, Carotid artery calcification, Dental Plaque	Altered Intercellular Communication	Regardless of clinical outcome, a strong inverse correlation was found between the extent of carotid plaque calcification and the intensity of plaque fibrous cap inflammation as determined by the degree of macrophage infiltration.	15297819
Inflammation	Altered Intercellular Communication	Elevation of the soluble thrombomodulin levels is associated with inflammation after percutaneous coronary interventions.	15298041
Inflammation, myocardial injury	Altered Intercellular Communication	The elevation of the soluble TM after PCI shows better correlation with inflammation than myocardial injury, indicating an endothelial origin.	15298041
allergic inflammation	Altered Intercellular Communication	CRTH2/DP2 on basophils may afford opportunities for therapeutic targeting in allergic inflammation.	15298571
Inflammation	Altered Intercellular Communication	Inflammation and activity scores in antrum with H. pylori infection were higher in men, but scores declined according to age.	15298601
Intestinal metaplasia, Atrophic	Altered Intercellular Communication	Levels of acute and chronic inflammations, atrophy and intestinal metaplasia scored according to the Sydney System were compared by stomach site and by sex.	15298601
Gastritis	Altered Intercellular Communication	Furthermore, anti-HpU IgY combined with antacids appears to ameliorate gastric inflammation.	15298626
Inflammation, Gastrointestinal Agents, Disease, Diabetes Mellitus	Altered Intercellular Communication	Trigonella foenum graecum (fenugreek) is traditionally used to treat disorders such as diabetes, high cholesterol, wounds, inflammation, and gastrointestinal ailments.	15298963
Choroiditis, Periphlebitis	Altered Intercellular Communication	Two weeks later, choroidal inflammation recurred and periphlebitis developed.	15300097
Inflammation, Erythema	Altered Intercellular Communication	The features of this condition are severe local inflammation, positive foreign body sensation, erythema, and lacrimation.	15300116
Inflammation, Malignant Neoplasms, Pseudomonas aeruginosa	Altered Intercellular Communication	An open biopsy specimen showed evidence of chronic inflammation without evidence of malignancy, and culture of the tissue grew Pseudomonas aeruginosa.	15301132
Inflammation	Altered Intercellular Communication	For comparison, serological, functional, and typical immunohistochemical markers of inflammation were detected.	15301240
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	Although patients with RA as compared to OA had highly significantly increased signs of inflammation, the density of CD1a+, CD1b+, and CD1c+ synovial cells was similar This was also true for the density of CD1+ cells in relation to that of activated CD163+ macrophages.	15301240
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	Considering the high synovial inflammation in patients with RA, the densities of CD1a+, CD1b+, and CD1c+ synovial cells were low compared to patients with OA.	15301240
Inflammation, Neuralgia	Altered Intercellular Communication	It can be nociceptive due to tissue inflammation, which mostly occurs during episodes of immune activation or neuropathic due to damage or dysfunction of the nervous system.	15301591
Inflammation, Cardiac cachexia, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Chronic heart failure (CHF) is a state associated with systemic inflammation, particularly in patients with cardiac cachexia.	15301893
Airway structure, ARCN1 gene	Altered Intercellular Communication	Characteristics of airway inflammation and bronchodilator reversibility in COPD: a potential guide to treatment.	15302720
Airway structure, ARCN1 gene	Altered Intercellular Communication	Factors related to airway inflammation and bronchodilator reversibility may be important in the management of stable COPD patients.	15302720
ARCN1 gene, Inflammation	Altered Intercellular Communication	Eosinophilic inflammation may play a substantial role in COPD, while neutrophils and IL-8 may have a great influence on nonreversible obstructive airways.	15302720
Airway structure, ARCN1 gene	Altered Intercellular Communication	The assessment of airway inflammation and bronchodilator responses can help the selection of specific therapies and the prediction of clinical outcomes for COPD patients.	15302720
Inflammation, Blood Clot	Altered Intercellular Communication	CD40 ligand (L) may promote inflammation and thrombus formation, and we hypothesized that CD40L could be involved in the pathogenesis of PAH.	15302794
Hepatic inflammation, Alopecia, CTCAE, Fever, CTCAE, Peeling of skin	Altered Intercellular Communication	An 11-year-old girl receiving phenobarbital developed fever, exfoliative skin rash, mucous membrane lesions, alopecia, and hepatic inflammation.	15304627
Irritation - emotion, Inflammation, Sciatic nerve compression, KANTR gene	Altered Intercellular Communication	However, prolonged sitting and weight bearing in the upright position after cesarean delivery can cause sciatic nerve compression at the sacroiliac joint with concomitant irritation, inflammation, and spasm of the piriformis muscle.	15305258
Asthmatic Airway Remodeling, Obesity	Altered Intercellular Communication	The relation between obesity and asthmatic airway inflammation.	15305944
Airway structure, Obesity	Altered Intercellular Communication	However, the relation between obesity and airway inflammation remains unclear.	15305944
Arterial Stiffness, Inflammation	Altered Intercellular Communication	This may suggest a role of inflammation in the development of arterial stiffness.	15306182
Inflammation, Gastritis	Altered Intercellular Communication	By two weeks post challenge gastric histology showed typical chronic H pylori gastritis with intense acute and chronic inflammation.	15306577
Gastrointestinal inflammation	Altered Intercellular Communication	While the chemokine receptor CCR9 and its chemokine ligand CCL25 (TECK) mediate lymphocyte homing to the healthy small intestine, the chemokine receptors important for recruitment during intestinal inflammation are undefined.	15306587
Inflammation	Altered Intercellular Communication	The patient was treated with 3 intravenous doses of Infliximab achieving complete remission of the scleral inflammation within four weeks.	15306969
Inflammation	Altered Intercellular Communication	This inflammation may lead in future to the aseptic loosening of the implant.	15307384
Inflammation	Altered Intercellular Communication	Taken together, our data suggest that 4-1BB/4-1BBL interactions contribute to the persistence of gut inflammation in CD.	15308117
Inflammation, Gastrointestinal symptom	Altered Intercellular Communication	The existence of autoantibodies was not associated with gastrointestinal symptoms but sustains the presence of a pathophysiological link between bowel inflammation and SpA.	15308872
Inflammation, Intervertebral Disc Degeneration	Altered Intercellular Communication	Enzymatic breakdown of the extracellular matrix, and possibly local inflammation, contributes to intervertebral disc degeneration.	15308963
Inflammation, Thrombocytosis, Leukocytosis	Altered Intercellular Communication	Laboratory data suggested severe inflammation with marked leukocytosis, thrombocytosis and elevated serum levels of C-reactive protein, G-CSF and IL-6.	15309018
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic Syndrome X, Cardiovascular Diseases	Altered Intercellular Communication	Low-grade inflammation has been implicated in the development of Type 2 diabetes and cardiovascular disease, but its role in the pathogenesis of the metabolic syndrome is unclear.	15309290
Inflammation, Metabolic Syndrome X, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Low-grade inflammation may increase the risk of the metabolic syndrome and diabetes in middle-aged men, but some of the risk is mediated through obesity and factors related to insulin resistance.	15309290
Inflammation, Granulomatosis with polyangiitis, Glomerulonephritis, Vasculitis, CTCAE	Altered Intercellular Communication	Wegener's granulomatosis (WG) is defined as a granulomatous inflammation of the upper and lower respiratory tract and systemic vasculitis of small and medium sized vessels which is often accompanied by a necrotizing glomerulonephritis.	15309321
Inflammation, Infection of bloodstream	Altered Intercellular Communication	Laboratory markers of systemic inflammation as predictors of bloodstream infection in acutely ill patients admitted to hospital in medical emergency.	15309668
Inflammation, Community-Acquired Infections	Altered Intercellular Communication	Markers of systemic inflammation were studied in 92 patients with community-acquired infection.	15309668
Communicable Diseases, Inflammation, Fever, CTCAE, Community-Acquired Infections	Altered Intercellular Communication	In conclusion, markers of systemic inflammation do not improve the diagnosis of community-acquired bloodstream infection; however, they may aid in identifying patients with fever due to occult infection.	15309668
allergic inflammation	Altered Intercellular Communication	ICAM-1 and IL-6 are important cytokines in the allergic inflammation in airway.	15311501
allergic inflammation	Altered Intercellular Communication	The closely correlation was observed between the allergic inflammation in upper and lower airway, so that the upper and lower airway should be treated as a united one.	15311501
Inflammation, Panniculitis	Altered Intercellular Communication	Physical examination showed signs of inflammation of the abdominal wall, and histological examination revealed severe panniculitis.	15311731
Inflammation, Hyphema, Choroidal Detachment	Altered Intercellular Communication	The V-P group showed a significantly less inflammation, hyphema and choroidal detachment than that in the T-P group.	15312620
Inflammation, Necrosis	Altered Intercellular Communication	Another patient had progressive enhancement and low relative cerebral blood volume and flow; biopsy showed necrosis and inflammation.	15313712
Inflammation	Altered Intercellular Communication	Chronic inflammation and impaired coronary vasoreactivity in patients with coronary risk factors.	15313940
Inflammation, Observation Method - Coagulation, square decimeter, Fibrosis Assessment, Thrombus	Altered Intercellular Communication	More fibrosis and thrombotic complications but similar expression patterns of markers for coagulation and inflammation in symptomatic plaques from DM2 patients.	15314081
Inflammation	Altered Intercellular Communication	Increased WM perfusion may indicate increased metabolic activity possibly due to increased cellularity and inflammation.	15314117
Inflammation, Arteriosclerosis, Malnutrition, Infection	Altered Intercellular Communication	Although malnutrition is not normally listed among the most frequent causes of mortality in these patients, it contributes to cardiovascular mortality through the MIA syndrome (Malnutrition, inflammation and arteriosclerosis) and the severity of infections.	15315117
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Accumulating epidemiologic and molecular evidence suggest that inflammation is an important component in the etiology of prostate cancer.	15316060
Inflammation	Altered Intercellular Communication	Macrophage-inhibitory cytokine-1 (MIC-1), a member of the transforming growth factor beta superfamily, is thought to play an important role in inflammation by regulating macrophage activity.	15316060
Bronchocentric granulomatosis	Altered Intercellular Communication	Bronchocentric granulomatosis is an unusual pathologic entity that is characterized by a necrotizing granulomatous inflammation surrounding the airways.	15316218
Inflammation	Altered Intercellular Communication	There was no evidence of suppurative inflammation of the appendix, and she made a good recovery following laparoscopic appendicectomy.	15316425
Colitis, Diverticulosis, Deficiency of butyryl-CoA dehydrogenase, Acute and chronic inflammation, Diverticulum	Altered Intercellular Communication	Segmental colitis associated with diverticulosis (SCAD) has been defined as chronic colonic inflammation surrounding diverticula with rectal sparing.	15316721
Colitis	Altered Intercellular Communication	No cases of extension of colonic inflammation in diverticula-free areas were found.	15316721
Inflammation, Low Vision	Altered Intercellular Communication	The following were predictive of a poorer visual prognosis: pan-uveitis (p = 0.0005), bilateral inflammation (p = 0.0005), increasing duration of reduced vision (p = 0.0005), an Indian or Pakistani ethnic background (p = 0.004), and increasing patient age (p = 0.02).	15317708
Inflammation, Unspecified visual loss	Altered Intercellular Communication	Older patients with bilateral inflammation and an increasing duration of reduced vision are at the greatest risk of severe visual loss (< or =6/60).	15317708
Inflammation, Obesity, Fatty Liver Disease	Altered Intercellular Communication	In addition to these factors, genetic predispositions to obesity and inflammation in the Japanese population were shown to contribute much to the development of NASH.	15318095
Bone Diseases	Altered Intercellular Communication	One hundred female patients were selected from applicants for panoramic radiological services who did not have a history of systemic bone disease, hysterectomy, or taking hormonal supplements.	15318252
Sjogrens Syndrome", Inflammation, GYPB gene	Altered Intercellular Communication	Primary Sjogren's syndrome (SS) is characterized by inflammation in salivary and lachrymal glands, with a local predominance of Th1-like cytokines, as well as the pleiotropic cytokine interleukin (IL) 18.	15320916
Refractory anemias, Gout	Altered Intercellular Communication	Addition of exogenous neurotransmitter glutamate significantly increased TNF-alpha levels in primary cell cultures derived from RA and gout patients.	15320917
Refractory anemias, Degenerative polyarthritis, Gout	Altered Intercellular Communication	The SF neurotransmitter EAA levels significantly correlated to selected SF chemokine levels, in clinically active RA, gout and OA patients, independent of disease.	15320917
Arthritis	Altered Intercellular Communication	These data expand the relationship of SF neurotransmitter EAA levels to SF cytokines and chemokines in patients with clinically active arthritis, and suggest that neurotransmitters Glu and Asp contribute to peripheral inflammatory processes.	15320917
Arthritis	Altered Intercellular Communication	These data expand the relationship of SF neurotransmitter EAA levels to SF cytokines and chemokines in patients with clinically active arthritis, and suggest that neurotransmitters Glu and Asp contribute to peripheral inflammatory processes.	15320917
Inflammation, Helicobacter pylori	Altered Intercellular Communication	Helicobacter pylori-induced mucosal inflammation results in high production of interleukin 17 (IL-17), a potent inducer of IL-8 in gastric epithelial cells.	15321994
Inflammation	Altered Intercellular Communication	The inflammation scores in the blood were high and he had a moderate increase in pancreatic enzymes.	15322706
Inflammation	Altered Intercellular Communication	In addition, the clinical response was significantly better with CIP/DEX than with N/P/H at Days 3 and 18 (p = 0.0279 and p = 0.0321, respectively), as was the reduction in ear inflammation at Day 18 (p = 0.0268).	15324520
Atherogenesis, Communicable Diseases, Inflammation, Thrombosis of blood vessel	Altered Intercellular Communication	The possibility that infectious agents may unchain biological and biochemical reactions related to inflammation, atherogenesis, and vascular thromboses events have recently been described.	15325506
Inflammation, Eczema, Paget Disease	Altered Intercellular Communication	Histological diagnosis confirmed eczema in 24, Paget's disease of nipple in 9 and chronic inflammation in 2.	15325673
Inflammation, Thrombophilia, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Predictive value of indexes of inflammation and hypercoagulability on success of cardioversion of persistent atrial fibrillation.	15325942
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Although inflammation may be associated with "permanence" of atrial fibrillation, indexes of platelet activation, endothelial damage/dysfunction, or coagulation showed no relation to the immediate and long-term (2-month) cardioversion outcome.	15325942
Inflammation, Endothelial dysfunction, Cardiovascular Diseases	Altered Intercellular Communication	Myeloperoxidase-mediated endothelial dysfunction may be an important mechanistic link between oxidation, inflammation, and cardiovascular disease.	15326065
Inflammation, Apolipoprotein E	Altered Intercellular Communication	Apolipoprotein E (apoE) polymorphism plays a central role in lipid metabolism, but has recently also been suggested to regulate inflammation, as judged by levels of serum C-reactive protein (CRP).	15328426
Sjogrens Syndrome", Inflammation, PEELING SKIN SYNDROME	Altered Intercellular Communication	To establish whether polymorphism of the apoE genes affects susceptibility to primary Sjogren's syndrome (pSS), degree of inflammation or age of onset of pSS.	15328426
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	The degree of steatosis, inflammation and fibrosis on intraoperative wedge liver biopsy was determined and scored.	15329185
Degenerative polyarthritis, Pain Distress Question, Inflammation	Altered Intercellular Communication	The treatment of osteoarthritis, a disease that eventually affects the majority of the older population, involves the alleviation of symptoms such as pain and stiffness, and the reduction of inflammation.	15330493
Inflammation, Tension Headache, Migraine Disorders	Altered Intercellular Communication	Local inflammation as a mediator of migraine and tension-type headache.	15330822
Gingivitis, Migraine Disorders, Tension Headache	Altered Intercellular Communication	To demonstrate the relationship of migraine and tension-type headache to a localized maxillary gingival inflammation.	15330822
Migraine Disorders, Sore to touch, Inflammation, Tension Headache	Altered Intercellular Communication	Ipsilateral intraoral tenderness and increased local temperature were consistently observed during unilateral migraine and tension-type headache, suggesting local inflammation.	15330822
Inflammation, Headache	Altered Intercellular Communication	These results suggest that a local intraoral inflammation may be associated with the pathogenesis of these common headaches.	15330822
Inflammation, Granulomatous	Altered Intercellular Communication	Histopathological study revealed a granulomatous aspecific inflammation containing actinomycetes colonies.	15330828
Inflammation, Traumatic injury, Aggregation	Altered Intercellular Communication	Expression of transforming growth factor-beta1 (TGF-beta1), a regulator of brain responses to inflammation and injury, has been correlated with Abeta accumulation, aggregation and clearance in transgenic mice and increased production of amyloid precursor protein (APP) followed by Abeta generation in murine and human astrocyte cultures.	15331151
PTHLH gene, Paraneoplastic Syndromes, Hypercalcemia, CTCAE, Malignant Neoplasms	Altered Intercellular Communication	Humoral hypercalcemia of malignancy (HHM) is a common paraneoplastic disorder usually associated with increased synthesis of parathyroid hormone-related peptide (PTHrP).	15331405
Intestinal metaplasia, Inflammation, Helicobacter pylori, Gland	Altered Intercellular Communication	The scores for glandular atrophy and intestinal metaplasia were higher and the scores for chronic inflammation, polymorphonuclear neutrophil activity, and the density of Helicobacter pylori were lower in G-type than in I-type tumors.	15331925
Inflammation, Carcinoma, Infection caused by Helicobacter pylori, Gland, Intestinal metaplasia	Altered Intercellular Communication	The background mucosa of G-type carcinoma is associated with glandular atrophy and intestinal metaplasia, whereas that of I-type carcinoma is associated with active and chronic inflammation induced by H. pylori infection.	15331925
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The prevalence of inflammation is high among patients with chronic renal failure but the reason of inflammation is unclear.	15331941
Inflammation, Chronic Kidney Diseases, Ventricular Dysfunction, Fluid overload	Altered Intercellular Communication	We test the hypothesis that inflammation in chronic renal failure could be the consequence of an increased left-ventricular wall tension related to ventricular dysfunction, hypervolemia or both.	15331941
Inflammation, Kidney Failure	Altered Intercellular Communication	Our results suggest a link between left-ventricular filling pressure and inflammation in patients with advanced renal insufficiency.	15331941
Gout	Altered Intercellular Communication	One of the essential lines in the research of gout concerns mechanisms of SMC formation in organs and tissues and microcrystalline gastroduodenal inflammation.	15332576
Inflammation	Altered Intercellular Communication	Methods of correction of this inflammation are to be designed.	15332576
Inflammation	Altered Intercellular Communication	It acts as one of the adhesion proteins, binding to hyaluronan and is known to play a part in cell migration from vessels in inflammation.	15332592
Clostridium difficile, Inflammation, Diarrhea, pseudomembranous colitis	Altered Intercellular Communication	In Clostridium difficile associated diarrhoea (CDAD), histological changes in the colonic mucosa range from minimal inflammation to pseudomembranous colitis (PMC).	15333661
Inflammation, Diarrhea, pseudomembranous colitis	Altered Intercellular Communication	Colonic biopsies were obtained from 12 control patients with diarrhoea, six patients with CDAD and minimal inflammation, and 10 patients with CDAD with pseudomembranous colitis (samples obtained from areas with and without inflammatory exudate).	15333661
Inflammation, Granuloma	Altered Intercellular Communication	Biopsies showed chronic inflammation and a non-necrotizing granuloma.	15333976
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Intercellular adhesion molecule 1 plays an important role in the recruitment of leucocytes at sites of inflammation and is up-regulated in intestinal mucosa of inflammatory bowel disease.	15334773
Inflammation	Altered Intercellular Communication	The relative significance of focal macrophage infiltration and generalized coronary inflammation for predicting acute coronary events is a currently a source of considerable controversy in cardiology.	15337206
Tympanoplasty, Inflammation	Altered Intercellular Communication	This result can explain why grommet insertion or tympanoplasty is not beneficial to postirradiated ears, possibly because both operations spare the inflammation outside the middle ear cavity.	15337568
Interstitial Fibrosis Assessment	Altered Intercellular Communication	A kidney biopsy revealed 23 of 37 glomeruli obsolescent and advanced damage with over 50% of cortical tissue replaced by interstitial fibrosis and chronic inflammation.	15338393
Inflammation	Altered Intercellular Communication	To assess the applicability of serum concentrations of markers of synovial inflammation, cartilage, and bone metabolism in relation to conventional markers of disease activity, bone mineral density (BMD) of the hand, and radiographic outcome.	15338487
Inflammation, Lambert-Eaton Myasthenic Syndrome, Syndrome, Qi	Altered Intercellular Communication	Analysis of the changes of the related laboratorial indexes among the three types of syndrome showed that Type 1 mainly manifested asthenia syndrome with sthenia syndrome, and its indexes of AST, ALT, GGT levels were markedly higher than those of Type 2 and Type 3, both of which mainly showed sthenia syndrome with asthenia syndrome, and that Type 3 was in active inflammation, deficiency of both Qi and Yin (deficiency of Yin > deficiency of Qi), and its FN, Alb, FV, FVII, PLT, PCT levels were obviously reduced.	15339580
Inflammation, Acute respiratory failure	Altered Intercellular Communication	Dysregulated inflammation and altered metabolism may increase oxidative stress in ARF patients.	15339994
Ulcer, Inflammation, Specimen Source Codes - Abscess	Altered Intercellular Communication	In addition, objective adverse events (gingival inflammation, ulcers, abscess, cratering, and lesions) were recorded by the investigator on an adverse event form.	15341359
Inflammation, MARCKS wt Allele	Altered Intercellular Communication	As markers of inflammation, the major histocompatibility complex (MHC) class I and class II and the membrane attack complex (MAC) were analysed.	15342926
Inflammation, Chronic inflammation, Atherosclerosis, Necrotizing granulomatous inflammation, Pseudoaneurysm	Altered Intercellular Communication	Microscopically, 6 patterns were recognized: acute inflammation superimposed on severe chronic atherosclerosis (55%), atherosclerosis with chronic inflammation (20%), acute inflammation without atherosclerosis (7%), chronic adventitial inflammation (7%), pseudoaneurysm formation (7%), and necrotizing granulomatous inflammation (4%).	15343514
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Although cytologic examination suggested possible malignancy, a biopsy of the vaginal wall was diagnosed as chronic inflammation.	15343521
Cardiovascular Diseases	Altered Intercellular Communication	Inflammation variables (C-reactive protein [CRP], fibrinogen, and soluble intercellular adhesion molecule-1 [sICAM-1]) have been identified as risk factors for cardiovascular disease.	15345506
Inflammation, Malignant Neoplasms, Cardiovascular Diseases	Altered Intercellular Communication	It remains unclear to what extent the associations between low serum beta-carotene concentration and increased risk for cardiovascular disease and cancers are attributable to inflammation.	15345737
Inflammation	Altered Intercellular Communication	Three patients had chronic inflammation confirmed by both methods.	15350334
Inflammation, Acid reflux, Obstruction, Arteriopathic disease	Altered Intercellular Communication	Limbs with truncal saphenous reflux, deep vein reflux or obstruction, previous injection sclerotherapy or vein surgery, arterial disease and inflammation of non-venous origin were excluded from further consideration.	15350560
Atrial Fibrillation, Atrial Fibrillation by ECG Finding, Inflammation, Thrombophilia	Altered Intercellular Communication	Atrial fibrillation (AF) has been shown to confer a prothrombotic or hypercoagulable state, which could be related to inflammation.	15350843
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	We hypothesised a role for this polymorphism in the prothrombotic state and inflammation in AF, and tested this hypothesis by measurement of indices of coagulation (tissue factor (TF) and fibrinogen), inflammation (interleukin-6 (IL6)) and platelet activation (soluble P selectin (sPsel)).	15350843
Neurodegenerative Disorders	Altered Intercellular Communication	Microglial cells involved in the pathogenesis of many neurodegenerative diseases acquire the features of cytotoxic and phagocytic cells in response to certain pathogens and inflammatory signals.	15350960
Respiratory Diaphragm, Inflammation	Altered Intercellular Communication	Postoperatively, a delayed right diaphragmatic rupture occurred due to progressive inflammation and muscle devitalisation.	15351874
Refractory anemias, Fibrinoid necrotizing inflammation, Synovitis	Altered Intercellular Communication	The high correlation between intra-articular microvascular power Doppler flow and clinical synovitis in RA patients (P<0.0001) indicates that PDUS may be helpful in studying the role of synovial blood vessels in rheumatoid inflammation.	15353607
Airway structure, Pulmonary Emphysema	Altered Intercellular Communication	These patients had markedly heterogeneous emphysema and showed no radiologic signs of airway inflammation.	15354100
Parkinson Disease, palladium	Altered Intercellular Communication	Parkinson's disease (PD) is characterized by selective degeneration of neurons in the substantia nigra and subsequent dysfunction of dopaminergic neurotransmission.	15354386
Ovarian Tissue	Altered Intercellular Communication	In conclusion, the finding of alpha-inhibin positivity in MCN with ovarian-type stroma further supports its similarity to true ovarian stromal tissue and may suggest a role of complex hormonal interaction in the pathogenesis.	15354741
vascular inflammations, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Non-HDL cholesterol level is reliable to be an early predictor for vascular inflammation in type 2 diabetes mellitus.	15356091
Cancer-related fatigue, vascular inflammations	Altered Intercellular Communication	On the basis of CRP levels, non-HDL levels are reliable in predicting vascular inflammation, and CRF could be another important predictor for cardiovascular events.	15356091
Gingivitis, Orthodontic	Altered Intercellular Communication	Periodontal pathogens were associated with gingival inflammation during orthodontic treatment.	15356501
Gingivitis, Orthodontic	Altered Intercellular Communication	Periodontal pathogens associated with gingival inflammation during orthodontic treatment can be significantly reduced by orthodontic appliance removal and professional prophylaxis.	15356501
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide as a marker of airway inflammation for an epidemiologic study in schoolchildren.	15356549
Inflammation, Vulva	Altered Intercellular Communication	However, chronic inflammation of the vulvar vestibulae may contribute to the pathogenesis of ciliated cyst of the vulva.	15358576
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	However, scant descriptions have been allocated to associated stromal changes, such as prominent inflammation and fibrosis, which can overshadow a tumoral proliferation and masquerade as a benign reactive process and this has not been recognised as a histopathological variant.	15358712
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histological pitfalls in the biopsy were represented by mild atypical cuboidal or columnar epithelial cells lining bronchiolar structures resembling florid bronchiolar metaplasia in a background of extensive fibrosis and inflammation, features that mimicked inflammatory honeycombing.	15358712
Inflammation	Altered Intercellular Communication	Synovial inflammation was assessed by the scoring system of S. Lindblad and E. Hedfors.	15359508
Hemorrhage, Glaucoma, Neovascular, Uveitis	Altered Intercellular Communication	Among 14 eyeballs with severe acute intraocular inflammation, 7 eyeballs with suprachoroidal and supraciliary hemorrhage were found and one other such eyeball was seen among 53 with neovascular glaucoma.	15359905
Leucocytic infiltrate, Uveitis	Altered Intercellular Communication	In the eyeballs with severe acute intraocular inflammation, intraocular pressure was elevated and the blood vessels were weakened by inflammatory cell infiltration.	15359905
Communicable Diseases	Altered Intercellular Communication	In conclusion, infectious or inflammatory conditions can mimic metastatic disease and therefore add to the difficulty of stage determination.	15361216
Impaired cognition	Altered Intercellular Communication	The positive correlation between ACh deficit and cognitive impairment suggests that ACh is an important neurotransmitter for memory.	15361288
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To determine whether inflammation in the gut associated immune system is activated in rheumatoid arthritis (RA).	15361394
Subarachnoid Hemorrhage, Neurologic Symptoms	Altered Intercellular Communication	They manifest their occurrence by subarachnoid haemorrhage and neurological and hormonal symptoms, resulting from compression on either the nervous structures or on the pituitary.	15361819
Inflammation, Thick skin	Altered Intercellular Communication	Sonography and MRI examination disclosed tendon sheath thickening over extensor tendons of both wrists and fingers without features of active inflammation over tendons or joints nor thickening of skin.	15361946
Inflammation, Primary sclerosing cholangitis, Chronic disease, Destruction (action), Atrophic	Altered Intercellular Communication	Primary sclerosing cholangitis (PSC) is a chronic disease of autoimmunological etiology, leading to inflammation, destruction and atrophy of the bile ducts.	15362735
Microalbuminuria, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	According to our results acute-phase proteins a known markers of chronic inflammation were associated with microalbuminuria independently of clinical cardiovascular disease.	15364159
Blindness, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Both eyes deteriorated rapidly to blindness with progressive subretinal fibrosis and inflammation over 3 months, and the patient was unresponsive to systemic prednisolone and azathioprine.	15364234
Intraocular inflammation	Altered Intercellular Communication	Unless progressive intraocular inflammation occurs, close observational management is indicated.	15364241
Inflammation, Atherosclerosis	Altered Intercellular Communication	These observations establish the association of systemic inflammation with anatomically defined atherosclerosis in the general population.	15364672
Inflammation, Diabetes Mellitus, Coronary heart disease, Choline Dehydrogenase, Mitochondrial, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	We have examined markers of haemostasis and inflammation in men with diabetes, coronary heart disease (CHD) or both, and assessed their associations with insulin resistance in men with Type 2 diabetes.	15365613
Inflammation, Gastrointestinal mucositis	Altered Intercellular Communication	In the development of mucositis several mechanisms play a role, such as inflammation and the effect of radiation on the high proliferation rate of oral basal epithelial cells.	15365799
Inflammation, Tubular atrophy, Interstitial Fibrosis Assessment, Glomerulosclerosis (disorder)	Altered Intercellular Communication	As size and thickness of renal parenchyma seen on ultrasonography were normal, renal biopsy was performed and it showed glomerular sclerosis, diffuse tubular atrophy and interstitial fibrosis with inflammation.	15365968
Inflammation, Perforation (observation), Neoplasms	Altered Intercellular Communication	We concluded that the progress of the tumor and the mechanical inflammation were major cause of perforation of the tumor into the pericardial sac, and autodigestion by enzyme from pancreas was minor cause of perforation.	15366580
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation has been demonstrated to be an important risk factor for the development of cardiovascular disease (CVD).	15366640
Cholecystitis, Cholelithiasis, Inflammation, Perforation of gallbladder	Altered Intercellular Communication	Gallbladder perforation is an almost exclusive complication of cholecystitis, which accompanies severe inflammation of the gallbladder with or without cholelithiasis.	15366646
deficiency aspects, Acromegaly	Altered Intercellular Communication	To assess the surgical outcome of hypophysectomy in acromegalic patients, differences in response to surgery in micro and macroadenoma and the development of associated hormonal deficiency after surgery.	15366797
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The aim of the study was to assess the role of extracellular cytochrome c as an inducer of joint inflammation and to examine its levels in sera and synovial fluids of rheumatoid arthritis (RA) patients.	15367748
Inflammation	Altered Intercellular Communication	Our findings demonstrate that extracellular cytochrome c displays direct proinflammatory properties mediated by activation of NF-kappaB and causing neutrophil and monocyte triggered inflammation.	15367748
Refractory anemias, Inflammation	Altered Intercellular Communication	We hypothesize that decreased levels of cytochrome c in RA patients reflect consumption of this molecule in the synovial tissue, decreasing apoptosis and shifting the balance towards inflammation.	15367748
Hepatitis, FAM126A gene	Altered Intercellular Communication	These results suggest that SVRs, albeit free of occult HCV and/or HBV infection(s) over a decade, retain mild liver inflammation and the risk of HCC.	15368524
Communicable Diseases, Inflammation	Altered Intercellular Communication	We suggest that TB infection must be considered in the differential diagnosis whenever a patient presents with a chronic wrist or hand inflammation that is non-responsive to steroid treatment.	15368637
Disability, Inflammation, Muscle (organ)	Altered Intercellular Communication	The number of remaining teeth may indicate the extent of life-long exposure to inflammation, a known risk factor for muscle loss and consequent disability.	15369018
Inflammation	Altered Intercellular Communication	The presence of oral inflammation may lead to loss in muscle strength increasing the risk of disability.	15369018
Inflammation, Ulceration, CTCAE, Fever, CTCAE, Bite of mosquito	Altered Intercellular Communication	We describe a 73-year-old woman who developed fever and inflammation with ulceration at the site of mosquito bites in the lower thigh.	15370264
Granulomatous inflammation, Granulomatous Cheilitis, Edema	Altered Intercellular Communication	Granulomatous cheilitis (GC) is a chronic edema which frequently affects the upper lip due to granulomatous inflammation.	15370404
Inflammation	Altered Intercellular Communication	Correlation between COX-2 expression and neutrophil score in the antrum (r = 0.214, P = 0.042) and inflammation in the corpus (r = 0.234, P = 0.025) disappeared after eradication.	15371919
Berylliosis, Granulomatous inflammation	Altered Intercellular Communication	We monitored a cohort of beryllium-sensitized patients at 2-year intervals, using bronchoalveolar lavage and repeated transbronchial lung biopsies to determine progression to chronic beryllium disease as evidenced by granulomatous inflammation in lung tissue.	15374840
Inflammation, Atherosclerosis	Altered Intercellular Communication	Although endothelial activation markers in WG patients with inactive disease were not increased, the raised levels of hsCRP, MMPs, and TIMP-1 suggest that enhanced inflammation and excessive vascular remodelling are contributing factors in the development of accelerated atherosclerosis in WG.	15374854
Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Markers of inflammation (eg, interleukin-6 [IL-6]), and endothelial perturbation (von Willebrand factor [VWF], circulating endothelial cells [CECs]) are altered in acute coronary syndromes (ACS).	15374879
Sclerosis, Lesion, Inflammation	Altered Intercellular Communication	Intriguingly, protein oxidation was significantly increased within the dermis of LS lesions, indicating oxidative protein damage in the areas of sclerosis and inflammation.	15377350
Inflammation, Data types - Address	Altered Intercellular Communication	Polymorphisms within IL-1A influence the degree of brain microglial cell activation, especially in bearers of APOE epsilon4 allele, reinforcing the importance of neuroinflammatory processes in the pathogenesis of AD, and supporting the rationale for treating the disease with inflammation modulating drugs.	15377701
Orbital Pseudotumor	Altered Intercellular Communication	Infliximab in the treatment of recalcitrant idiopathic orbital inflammation.	15377906
Orbital Pseudotumor	Altered Intercellular Communication	A 15-year-old boy had bilateral idiopathic orbital inflammation refractory to treatment with corticosteroids.	15377906
Necrotizing granulomatous inflammation, Cyst, Calcinosis	Altered Intercellular Communication	Histopathologic examination of the excised mass disclosed a cyst with chronic granulomatous inflammation and calcification of the cyst wall.	15377914
Inflammation, Pneumonia, Bronchiolitis Obliterans Organizing Pneumonia, Bronchiolitis, Bronchiolitis Obliterans	Altered Intercellular Communication	Bronchiolitis obliterans with organizing pneumonia (BOOP) is characterized by excessive proliferation of granulation tissue within small airways (proliferative bronchiolitis) and alveolar ducts associated with chronic inflammation in the surrounding alveoli.	15378265
Inflammation	Altered Intercellular Communication	Retention of sponge fragments is rare but may be a cause of bleb inflammation as a result of a foreign body granulomatous reaction.	15378381
Inflammation, Coronary heart disease	Altered Intercellular Communication	Association between leisure time physical activity and markers of chronic inflammation related to coronary heart disease.	15380453
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Some markers of chronic inflammation have been recognized as predictors of cardiovascular risk in apparently healthy subjects and in patients with coronary heart disease (CHD).	15380453
Inflammation, Metabolic Syndrome X, Chronic Kidney Diseases	Altered Intercellular Communication	After similar adjustment, the metabolic syndrome was associated with (odds ratio; 95% confidence interval) low apolipoprotein A1 (2.27: 1.30,3.96), high apolipoprotein-B (2.97: 2.03,4.34), a higher HOMA insulin resistance index (5.25: 4.16, 6.63), chronic kidney disease (2.27: 1.42, 3.63), and elevated markers of inflammation [high white blood cell count (1.55: 1.14, 2.10), and elevated C-reactive protein (1.46: 1.06, 2.00)].	15380800
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	To determine whether chronic intestinal inflammation alters glutamine utilization, six 31 +/- 6 yr-old patients with Crohn's disease and an age-matched group of 6 healthy subjects received 7-h intravenous infusions of L-[5,5,5-2H3]leucine, along with an infusion of L-[1-13C]glutamine delivered intravenously for the first 3.5 h, and via a nasogastric tube for the subsequent 3.5 hrs.	15380910
Inflammation	Altered Intercellular Communication	Similarly, intestinal permeability increased during active inflammation but not in depleted patients.	15380915
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	The treatment of rheumatoid arthritis has become more intensive over the past 2 decades, resulting in tighter control of inflammation and lower levels of disability.	15381644
Inflammation, Coronary Artery Disease, Angina Pectoris	Altered Intercellular Communication	Markers of inflammation and rapid coronary artery disease progression in patients with stable angina pectoris.	15381646
Communicable Diseases, Inflammation, Intrahepatic biliary tree	Altered Intercellular Communication	In conclusion, these findings suggest that in the intrahepatic biliary tree, hBD-2 is expressed in response to local infection and/or active inflammation, whereas hBD-1 may constitute a preexisting component of the biliary antimicrobial defense system.	15382127
Hyperlipidemia, Fatty degeneration, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	There were no differences between both groups regarding age, gender, diabetes, hyperlipidemia, ALT levels, AST-to-ALT ratio levels, albumin levels, prothrombin activity, steatosis, or inflammation.	15382171
Communicable Diseases, Preauricular Fistulae, Congenital, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The fistulae were lined by squamous epithelium and smooth muscle without evidence of malignancy, infection or chronic inflammation that were histologically compatible with congenital fistulae.	15384715
Humor, Uveitis	Altered Intercellular Communication	Cytology of the aqueous humor essentially facilitated the differential diagnosis in 16 cases with an anterior uveal inflammation clinical picture.	15385197
Humor	Altered Intercellular Communication	In selected cases, cytology of the aqueous humor reveals specific, with regard to the clinical entity, cell populations and other elements and thus contributes effectively to the differential diagnosis and therapeutic approach to some anterior uvea inflammations.	15385197
Inflammation, Edema	Altered Intercellular Communication	In prediction of long-term graft function, the semiquantitative method was superior, indicating that accumulation of matrix molecules other than fibrillary collagens, oedema and inflammation are also important in graft prognosis.	15385637
Granulomatous inflammation, Mycobacterium Infections	Altered Intercellular Communication	Histological analysis revealed a granulomatous inflammation consistent with a mycobacteriosis.	15386205
Liver Dysfunction, Fatty Liver Disease	Altered Intercellular Communication	This case suggests that the altered sex hormone balance might exacerbate NASH because liver dysfunction was particularly worsened after bilateral high orchiectomy.	15387271
Barrett Esophagus, Inflammation	Altered Intercellular Communication	Activation of NFkappaB represents the central event in the neoplastic progression associated with Barrett's esophagus: a possible link to the inflammation and overexpression of COX-2, PPARgamma and growth factors.	15387324
Inflammation, Spondylarthritis	Altered Intercellular Communication	Histological evidence that infliximab treatment leads to downregulation of inflammation and tissue remodelling of the synovial membrane in spondyloarthropathy.	15388510
Inflammation	Altered Intercellular Communication	The study provides histological evidence that TNF alpha blockade not only downregulates inflammation but also leads to tissue remodelling.	15388510
Inflammation, Myocardial	Altered Intercellular Communication	The clinical significance of biochemical markers of myocardial damage or inflammation has not been prospectively established in populations representing the whole spectrum of acute coronary syndromes.	15389226
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	Inflammation has been associated with AF, but the prognostic significance of inflammatory mediators, such as interleukin-6 (IL-6) and C-reactive protein (CRP), among patients with AF is unknown.	15389233
Cessation of life, Inflammation, Cerebrovascular accident	Altered Intercellular Communication	In this pilot study, high plasma IL-6 levels were an independent predictor of stroke and the composite end point of stroke or death, suggesting that inflammation in AF may predict a poor prognosis.	15389233
Inflammation, Prostatic Neoplasms	Altered Intercellular Communication	The high expression of LEDGF/p75 in prostate tumors and BPH could be induced by inflammation and oxidative stress.	15389814
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	We examined cross-sectionally the association of serum C-reactive protein concentration, a non-specific marker of inflammation, and lower urinary tract symptoms (LUTS), suggestive of BPH.	15389816
Inflammation	Altered Intercellular Communication	These results suggest that elevated circulating C-reactive protein concentration might be an indicator of intraprostatic inflammation in symptomatic BPH.	15389816
Gliosis, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Crush preparations and frozen sections showed acute and chronic inflammation, gliosis, fibrosis, and many foreign body giant cells reacting to parasitic larval tissue.	15446590
Inflammation, Neutrophil Infiltration	Altered Intercellular Communication	The elevation of HNPs is presumably secondary to H.pylori-associated gastric inflammation involving neutrophil infiltration.	15447750
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation is important to the development of cardiovascular disease (CVD), and several dietary factors are thought to exert significant effects on inflammation and thus on the risk of CVD.	15447891
Inflammation	Altered Intercellular Communication	A relation exists between moderate-to-high coffee consumption and increased inflammation process.	15447891
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Major dietary patterns are related to plasma concentrations of markers of inflammation and endothelial dysfunction.	15447916
Necrotizing granulomatous inflammation, Granuloma, Caseous necrosis	Altered Intercellular Communication	Histopathological examination of the enucleated eye revealed necrotizing granulomatous inflammation, multiple epitheloid cell granulomas, and Langhan's giant cells, along with large areas of caseous necrosis.	15448600
APP gene, vascular inflammations, Aortic Aneurysm, Abdominal, Atherosclerosis	Altered Intercellular Communication	Vascular inflammation is implicated in the pathogenesis of atherosclerosis and abdominal aortic aneurysm (AAA), and is thought to involve reactive species such as the nitric oxide-derived oxidant peroxynitrite.	15449265
Inflammation, Claudication (finding)	Altered Intercellular Communication	Patients with an AAA had raised levels of circulating nitrated proteins compared with patients with claudication and controls, suggesting a greater degree of ongoing inflammation that was not related to smoking.	15449265
Inflammation	Altered Intercellular Communication	An increase of the amount of these cells was registered at the initial stages of inflammation, whereas chronic and destructive states were accompanied by the cells decrease.	15449684
Inflammation, Helicobacter pylori, Peptic Ulcer	Altered Intercellular Communication	Does seropositivity for Helicobacter pylori antibodies increase outpatient costs for gastric and duodenal ulcer or inflammation?	15449962
Inflammation, Peptic Ulcer	Altered Intercellular Communication	No studies have determined whether there are differences in the direct medical costs associated with gastric/duodenal ulcer or inflammation, between seropositive and seronegative patients.	15449962
Inflammation, Peptic Ulcer	Altered Intercellular Communication	To examine the relationship between seropositivity for H. pylori and outpatient visits and direct medical costs for gastric/duodenal ulcer or inflammation in Japan from the perspective of the payor and patients.	15449962
Inflammation, Peptic Ulcer	Altered Intercellular Communication	The annual outpatient incidence of disease, the number of visits to physicians, and the medical costs for gastric or duodenal ulcer or inflammation were about 2-fold greater in individuals with antibodies to H. pylori compared with those without antibodies.	15449962
Inflammation, Cachexia	Altered Intercellular Communication	Risk factors relating blood markers of inflammation and nutritional status to survival in cachectic geriatric patients in a randomized clinical trial.	15450049
Weight Gain, Inflammation	Altered Intercellular Communication	Interventions to modify levels of these cytokines or their receptors and improvement in nutritional status by weight gain might be helpful in ameliorating undetected chronic inflammation and thus might prolong the survival of these nursing home residents.	15450049
Inflammation, Thin-cap fibroatheroma	Altered Intercellular Communication	Furthermore, microvessel density is increased in lesions with inflammation, with intraplaque hemorrhage, and in thin-cap fibroatheromas.	15451780
Inflammation, atherosclerotic	Altered Intercellular Communication	Chronic inflammation represents an essential feature of the atherosclerotic process.	15451783
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Gastrin releasing peptide (GRP) and neuromedin B are bombesin (BN)-like peptides involved in regulating motility and inflammation in the gastrointestinal tract, which may be useful in treating inflammatory bowel disease (IBD).	15452158
Inflammation, Disease	Altered Intercellular Communication	None of the patients suffered from acute inflammation, connective or tumor disease.	15452392
Pneumonia, Interstitial, Interstitial inflammation	Altered Intercellular Communication	The clinical features are mild comparing with usual interstitial pneumonia and its histological features include a predominant degree of interstitial inflammation and a rare areas of honey combing, the lesions are temporally uniform.	15453035
Asphyxia, Neurotransmitters, Impaired cognition	Altered Intercellular Communication	In previous work, we have shown that perinatal asphyxia (PA) in the rat leads to life-long neurotransmitter deficits and impairment of cognitive functions and behavior.	15453273
Inflammation, Bronchial Hyperreactivity	Altered Intercellular Communication	In contrast, little is known about the relationship between bronchial hyperresponsiveness (BHR) and systemic inflammation.	15454657
Degeneration of lumbar intervertebral disc, Pain Distress Question, Inflammation	Altered Intercellular Communication	However, no reports have studied if there are also inflammatory cytokines in the facet joint, which generated arthropathic changes in degenerative lumbar spinal disorder and if pain is caused by chemical factors associated with inflammation such as inflammatory cytokines.	15454697
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Multiple open biopsies from the gland were necessary to demonstrate the presence of necrotizing granulomatous inflammation with vasculitis.	15454762
Inflammation, Infectious agent	Altered Intercellular Communication	The role of infectious agents and their contribution to the inflammation in chronic sinusitis/nasal polyposis (CS/NP) is not clear.	15454779
Dermatitis, Atopic, Asthma, Psoriasis	Altered Intercellular Communication	Staphylococcal and streptococcal toxins have superantigen activity and have been implicated in inflammatory conditions such as atopic dermatitis, psoriasis, and asthma.	15454779
Acute Coronary Syndrome, Thrombosis, Inflammation	Altered Intercellular Communication	Interaction between inflammation and thrombosis in acute coronary syndrome.	15457277
Acute Coronary Syndrome, Thrombosis, Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation and thrombosis are important in the pathogenesis of acute coronary syndrome (ACS).	15457277
Inflammation, Coronary heart disease	Altered Intercellular Communication	Cytokines [interleukin-1beta (IL-1beta) and interleukin-6 (IL-6)] are inflammation markers which play a major role in the development of coronary heart disease.	15457277
Inflammation, Thrombosis, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Our data suggest that there is a positive correlation between inflammation and thrombosis markers in patients with ACS.	15457277
Airway structure, Respiratory Tract Diseases	Altered Intercellular Communication	Exhaled nitric oxide (eNO) concentration measurement may permit the noninvasive estimation of the severity of airways inflammation in respiratory tract diseases.	15459140
Hypertrophy, Autoimmune Pancreatitis, Calcinosis, Pancreatitis	Altered Intercellular Communication	Features that suggest autoimmune pancreatitis include focal or diffuse pancreatic enlargement, with minimal peripancreatic inflammation and absence of vascular encasement or calcification at CT and endoscopic US, and diffuse irregular narrowing of main pancreatic duct, with associated multiple biliary strictures at ERCP.	15459324
glycation, Neurogenic Inflammation, Trauma, Nervous System	Altered Intercellular Communication	In this article, we summarize recent evidence why the receptor for advanced glycation end products and low-density lipoprotein receptor related protein 1 in the vascular CNS barriers are critical for regulation of Abeta homeostasis in the CNS and how altered activities in these 2 receptors at the blood-brain barrier may contribute to the CNS Abeta accumulation resulting in neuroinflammation, disconnect between the cerebral blood flow and metabolism, altered synaptic transmission, neuronal injury, and amyloid deposition into parenchymal and neurovascular lesions.	15459432
Inflammation	Altered Intercellular Communication	The results show in particular that laparoscopic resection for inflammation is not associated with increased morbidity.	15459774
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis is a severe, relapsing and remitting disease of the human large intestine characterised by inflammation of the mucosa and submucosa.	15460067
Inflammation, Esophageal	Altered Intercellular Communication	The mechanisms inducing mucosal inflammation are not completely defined, but oesophageal damage occurring when the caustic content of a drug remains in the oesophagus long enough to produce mucosal lesions seems to be a main factor.	15460849
Down Syndrome	Altered Intercellular Communication	Individuals with Down syndrome demonstrate neurotransmitter changes such as the loss of acetylcholine, norepinephrine, and serotonin (5-HT) with increasing age.	15461027
Vasculitis, Disease	Altered Intercellular Communication	Vasculitides constitute a heterogeneous group of diseases characterized by inflammation of blood vessels.	15461938
Epilepsy	Altered Intercellular Communication	It has been hypothesized that neurotransmitter dysfunction with persistent, pronounced excitatory or cytotoxic mechanisms may explain the continuous, erratic epileptic activity.	15464643
vascular inflammations	Altered Intercellular Communication	The EETs are potent endogenous vasodilators and inhibitors of vascular inflammation.	15466638
Inflammation, Data types - Address, Loading Technique	Altered Intercellular Communication	Epidemiological studies demonstrated that nonsteroidal anti-inflammatory drugs could prevent or delay the onset of LOAD suggesting inflammation may be involved in AD.	15468911
Inflammation, Cholestasis, Renal Cell Dysplasia, Carcinoma	Altered Intercellular Communication	Marked loss of the pattern was also seen in 16 out of the 24 (67%) other cirrhotic biopsies, as well as in cases with severe lobular inflammation and cholestasis and liver cell dysplasia and carcinoma.	15469471
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	CD10-stained bile canalicular pattern in liver biopsies is preserved in cases with mild fibrosis and inflammation, but it becomes increasingly reduced with the advance of fibrosis or the presence of severe lobular inflammation or extensive metastases.	15469471
melanoma, Inflammation	Altered Intercellular Communication	The immunohistochemical expression of Tn-C was studied in 98 primary melanomas and related to inflammation, invasion, and patient outcome.	15469480
Chronic meningitis, Abnormality of the cerebrospinal fluid, Meningitis	Altered Intercellular Communication	Chronic meningitis is defined as symptoms and signs of meningeal inflammation and persisting cerebrospinal fluid abnormalities such as elevated protein level and pleocytosis for at least one month.	15469610
Intraocular inflammation, Uveitis	Altered Intercellular Communication	Intraocular inflammation in uveitis implies compromise of immune privilege.	15470075
Inflammation, Metabolic Syndrome X, Coronary heart disease	Altered Intercellular Communication	HIV, metabolic syndrome X, inflammation, oxidative stress, and coronary heart disease risk : role of protease inhibitor exposure.	15470277
Inflammation, HIV Infections, Hypertriglyceridemia, Dyslipidemias, Obesity, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Although it is likely that the greatest proportion of CHD risk in the HIV+ subjects may be accounted for by pathological conditions linked to HIV infection in interaction with mediating processes such as inflammation, central obesity, and dyslipidemia, which was greater than in controls, it appears that PI medications may exacerbate oxidative stress and hypertriglyceridemia to enhance this risk.	15470277
Inflammation, Gallbladder	Altered Intercellular Communication	Xathogranulomatous inflammation is well known in the gall bladder and kidney.	15471123
Inflammation	Altered Intercellular Communication	Histopathological examination showed localized inflammation with numerous foamy histiocytes along with dilated ducts and microabscesses.	15471123
Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	Inflammatory gene load is associated with enhanced inflammation and early carotid atherosclerosis in smokers.	15472098
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation may provide a key mechanism by which smoking causes atherosclerosis.	15472098
Communicable Diseases, Inflammation	Altered Intercellular Communication	Somatostatin is expressed and secreted by human adipose tissue upon infection and inflammation.	15472172
Inflammation	Altered Intercellular Communication	SRIF expression and secretion are induced after inflammation in murine macrophages and in endotoxin-injected sheep and pigs.	15472172
Sepsis, Inflammation	Altered Intercellular Communication	Adipocyte mRNA abundance of SSTR 1-5 was differentially regulated by inflammatory treatments.Thus, human visceral adipose tissue secretes SRIF during inflammation and sepsis and expresses several SSTRs.	15472172
Inflammation	Altered Intercellular Communication	It is tempting to speculate that visceral adipose tissue-derived SRIF plays a modulatory role in the immunological and metabolic response to inflammation.	15472172
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	We hypothesized that prospective assessment of cytokine production by intestinal homing (beta7+) memory T cells in ulcerative colitis patients followed from remission to early relapse may elucidate shifts in cytokine production relevant to the mucosal environment associated with the early phase of inflammation.	15472508
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	The earliest phase of intestinal inflammation in ulcerative colitis patients is associated with an increase in both TH1 (TNF-alpha and TH2 (IL-4) cytokines by intestinal homing beta7+ memory T cells.	15472508
Communicable Diseases, Congenital MeSH qualifier, Traumatic injury, Inflammation	Altered Intercellular Communication	They are usually arteriosclerotic in origin, and may be congenital or secondary to injury, dissection, infection, inflammation, or Kawasaki disease (KD).	15473651
Synovitis, Inflammation, Joint swelling, Pain Distress Question	Altered Intercellular Communication	Clinical activity of MCP joint inflammation was classified according to a modified index for synovitis activity based on joint swelling, warmness and pain.	15474389
Cartilage destruction, Inflammation, Joint swelling	Altered Intercellular Communication	A single intravenous injection of FK228 (2.5 mg/ml) successfully inhibited joint swelling, synovial inflammation, and subsequent bone and cartilage destruction in mice with AMA.	15476220
vascular inflammations, Giant Cell Arteritis	Altered Intercellular Communication	Early recruitment of phagocytes contributes to the vascular inflammation of giant cell arteritis.	15476267
vascular inflammations, Giant Cell Arteritis	Altered Intercellular Communication	Vascular inflammation in giant cell arteritis is generally described as a process involving dendritic cells, T-lymphocytes, and effector tissue macrophages.	15476267
vascular inflammations, Giant Cell Arteritis	Altered Intercellular Communication	In conclusion, recently recruited phagocytes expressing pro-inflammatory S100 proteins take part in the vascular inflammation of giant cell arteritis.	15476267
Inflammation	Altered Intercellular Communication	These data indicate that phagocytes within the adventitia and media contribute to the process of inflammation via release of the pro-inflammatory S100 proteins S100A8, S100A9, and S100A12.	15476267
Canada, Chronic rejection of renal transplant	Altered Intercellular Communication	Gene expression profiles from kidneys with higher Banff chronic allograft nephropathy (CAN) scores confirmed significant up-regulation of genes responsible for immune/inflammation and fibrosis/tissue remodeling.	15476476
Inflammation, Dementia, Vascular	Altered Intercellular Communication	Chronic inflammation appears to play a role in the pathogenesis of vascular dementia.	15476562
Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation is typically treated with a combination of anti-inflammatory and anti-infective drugs.	15476908
Intraocular inflammation, THANATOPHORIC DYSPLASIA, TYPE I (disorder)	Altered Intercellular Communication	Intraocular inflammation was similar in the TD and DNP groups at all time points.	15476908
Inflammation, THANATOPHORIC DYSPLASIA, TYPE I (disorder)	Altered Intercellular Communication	At days 8, 14, and 21, inflammation scores were significantly lower with TD than with NPG (all, P < 0.05).	15476908
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Inflammation has a pathogenetic role in acute myocardial infarction (MI).	15477419
Inflammation, Viral meningitis	Altered Intercellular Communication	As in viral meningitis, procalcitonin might be able to discriminate between bacterial and chemical causes of CNS inflammation.	15477562
Inflammation	Altered Intercellular Communication	These results suggest that periodic intraventricular administration of anti-Abeta is a potentially useful method for rapid reduction of both preexisting amyloid load and associated inflammation, providing a window of 4 weeks' duration for possible pharmacological cotreatment(s) to prevent de novo Abeta formation.	15478192
Cough variant asthma, Inflammation, Coughing, Wheezing, Dyspnea, Respiratory Hypersensitivity	Altered Intercellular Communication	Although patients with cough variant asthma have cough with minimal wheezing and dyspnea, airway hyperresponsiveness from chronic inflammation is believed to be the underlying mechanism.	15478381
Inflammation	Altered Intercellular Communication	In order to identify the chronic inflammation, hsCRP measurement at several time are recommended.	15478618
Inflammation	Altered Intercellular Communication	The continuous higher value of CRP is observed as the signal of the chronic inflammation.	15478618
Granulomatous inflammation	Altered Intercellular Communication	Pathological findings of the nodule showed granulomatous inflammation.	15479307
Inflammation, Osteopenia, Crohn Disease	Altered Intercellular Communication	These findings further support the theory that active ongoing inflammation and high levels of circulating cytokines play a pivotal role in the pathogenesis of bone loss in patients with Crohn's disease.	15479356
Inflammation	Altered Intercellular Communication	In the colon, HD-5, HD-6, and sPLA2 were increased during inflammation in wild-type but not in NOD2 mutated patients.	15479689
Inflammation, Crohn Disease	Altered Intercellular Communication	As alpha defensins are important in the mucosal antibacterial barrier, their diminished expression may explain, in part, the bacterial induced mucosal inflammation and ileal involvement of Crohn's disease, especially in the case of NOD2 mutations.	15479689
Inflammation	Altered Intercellular Communication	The aorta was divided into three vascular regions (ascending aorta, aortic arch, and descending aorta) to localise the aortic inflammation and compare both imaging techniques.	15479905
Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	sPGII levels may be used as a reliable marker of H. pylori infection in the initial diagnosis as well as to evaluate H. pylori eradication and subsequent changes in gastric inflammation.	15479977
Fibrosis Assessment, Vasculitis, CTCAE, Acute and chronic inflammation, Hemorrhage	Altered Intercellular Communication	Pathologically, these findings corresponded to alveolar hemorrhages, interstitial chronic inflammation in the alveolar septa, vasculitis, or fibrosis.	15480049
Inflammation	Altered Intercellular Communication	This might result partly from a progressive nonspecific inflammation in the graft.	15480162
Inflammation, Leucocytic infiltrate, Necrosis	Altered Intercellular Communication	He had undergone multiple cytological smears of the inflammatory infiltration and biopsies of both the oral and nasal mucosa, which resulted in extensive necrotic debris and suppurative inflammation, and, on the very last biopsy, fungal hyphae, spores and conidia were also detected.	15480762
Inflammation, Acute inflammatory disease, Acute infectious disease	Altered Intercellular Communication	TSAT overreacts to inflammation, failing to reveal the correct status of available iron for erythropoiesis in acute inflammatory disease, but the use of CHr is expected to avoid these disadvantages, providing a reliable direct marker of iron status in the acute infection phase.	15480904
Barrett Esophagus, Stenosis, Duodenal Ulcer, Esophagitis, Gastric Ulcer, CTCAE 5	Altered Intercellular Communication	Primary endoscopic outcomes included esophageal inflammation and stricture, gastric ulcer, duodenal ulcer, suspected Barrett's esophagus (> or =2 cm), and suspected esophageal and gastric malignancy.	15480985
Appendicitis, CTCAE	Altered Intercellular Communication	LA is the procedure of choice for appendicitis regardless of age, sex, BMI, or degree of appendiceal inflammation.	15481290
Inflammation, Squamous metaplasia	Altered Intercellular Communication	Squamous metaplasia and inflammation increased the risk of relapse.	15481709
Refractory anemias, Inflammation	Altered Intercellular Communication	UrNTx and UrDPD correlated with markers of disease activity in patients with RA (erythrocyte -sedimentation rate and C-reactive protein), but not with -clinical signs of inflammation (swollen and tender joint counts).	15482266
Liver Cirrhosis	Altered Intercellular Communication	Implication of inflammation-related cytokines in the natural history of liver cirrhosis.	15482340
Communicable Diseases, Hypertension, CTCAE, Liver Cirrhosis	Altered Intercellular Communication	However, their role in the natural history of cirrhosis and portal hypertension, in the absence of infection, and the prognostic significance of inflammation-related cytokines have not been reported.	15482340
Cirrhotic	Altered Intercellular Communication	Our objective was the analysis of the prognostic value of inflammation-related cytokines in cirrhotic patients.	15482340
Cirrhotic	Altered Intercellular Communication	In addition to the classic factors implicated in mortality (Child-Pugh score and hemodynamic parameters), alterations in inflammation-related components are of prognostic significance in cirrhotic patients.	15482340
Inflammation, Chronic Kidney Diseases, Obesity	Altered Intercellular Communication	Association of obesity with inflammation in chronic kidney disease: a cross-sectional study.	15483779
Inflammation, Obesity, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	These data suggest that as in the general population, in CKD patients, obesity, a traditional risk factor for atherosclerosis, is associated with inflammation, a novel risk factor for atherosclerosis.	15483779
Inflammation, Absence of sensation	Altered Intercellular Communication	Slit-skin smears were negative in all patients, and skin histopathology from the area of sensory loss revealed non-specific inflammation in the dermis in a majority of patients, with perineural inflammation in a few.	15485285
Cessation of life, Inflammation, Heart failure, Autonomic nervous system disorders	Altered Intercellular Communication	Sudden unexpected death in heart failure may be preceded by short term, intraindividual increases in inflammation and in autonomic dysfunction: a pilot study.	15486117
Cessation of life, Inflammation, Chronic heart failure	Altered Intercellular Communication	To see whether sudden unexpected death in chronic heart failure is preceded by intraindividual worsening in inflammation and in ECG criteria.	15486117
alkanesulfonate monooxygenase activity, Inflammation, Autonomic nervous system disorders	Altered Intercellular Communication	This is preliminary evidence that SUD may be preceded by intraindividual increases in both inflammation and autonomic dysfunction.	15486117
ARCN1 gene	Altered Intercellular Communication	Sputum concentrations of GSSG and nitrosothiols are increased in patients with COPD and associated with neutrophilic inflammation.	15486372
palladium, Inflammation, Loading Technique	Altered Intercellular Communication	Several works have demonstrated the involvement of inflammation in the pathogenesis of both, PD and LOAD.	15488313
Inflammation, BDI - Functional Impairment	Altered Intercellular Communication	Peripheral blood markers of inflammation and functional impairment in elderly community-dwellers.	15489065
Inflammation, BDI - Functional Impairment	Altered Intercellular Communication	In conclusion, in elderly individuals, peripheral blood markers of inflammation are associated with functional impairment independently of potential confounders.	15489065
Inflammation	Altered Intercellular Communication	We conclude that obese older women with the MS are characterized by high lean mass, high visceral fat, and elevated sTNFR1, and the severity of the MS is associated with body composition, visceral adiposity, and inflammation.	15489217
Intestinal metaplasia, Inflammation, Dysplasia, Mucous Membrane	Altered Intercellular Communication	Specimens were evaluated for acute and chronic inflammation, lymphoid aggregates, proliferation, mucosal atrophy, intestinal metaplasia, dysplasia, and MUC5AC and MUC6 expression using histochemical and immunohistochemical methods.	15489580
Inflammation	Altered Intercellular Communication	There was a significant decrease in acute and chronic inflammation scores, from 1.48 +/- 1.10 to 0.23 +/- 0.63 and from 2.67 +/- 0.68 to 1.44 +/- 1.04, respectively (P < 0.001), and in a number of lymphoid follicles, from 42.68% to 21.95% of cases (P < 0.008).	15489580
Inflammation, Atherosclerosis, Chronic Kidney Diseases, Vascular calcification	Altered Intercellular Communication	Although evidence has accumulated indicating a close relationship between inflammation and atherosclerosis, the relationship between inflammation and vascular calcification in patients with chronic renal failure is unclear.	15490400
Inflammation, Calcinosis, Vascular calcification	Altered Intercellular Communication	In conclusion, the present study shows that increased levels of CRP are significantly associated with the presence of vascular calcification in both aorta and hand arteries (ie, with both atheromatous and medial forms of calcification), indicating evidence for a relationship between inflammation and vascular calcification in hemodialysis patients.	15490400
Asthma, Bronchitis	Altered Intercellular Communication	Cytological and oxidative characteristics of bronchial inflammation before and after treatment were studied in 35 elderly patients with severe bronchial asthma (BA).	15490732
Gingivitis	Altered Intercellular Communication	Myeloid-related protein (MRP)8/14 (calprotectin) and its subunits MRP8 and MRP14 in plaque-induced early gingival inflammation.	15491313
Cessation of life, Inflammation	Altered Intercellular Communication	It has been suggested that the type and phase of inflammation can be discriminated on the basis of differences in the expression of calprotectin and its subunits, released during activation and/or death of granulocytes and monocytes.	15491313
Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	During the experimental phase with no oral hygiene (days 0-10), the clinical parameters Plaque Index, Gingival Index (GI) and bleeding on probing increased as expected, confirming that plaque accumulation leads to gingival inflammation.	15491313
Immune-mediated	Altered Intercellular Communication	The interaction between CD40 and CD40L could be an important mechanism of cellular activation in cutaneous immune-mediated inflammation by induction of secretion of proinflammatory cytokines and chemokines.	15491417
Inflammation	Altered Intercellular Communication	There was a significant quantity of MPO+ cells (neutrophil granulocytes) in the inflamed tissue, and they might have a role in sustaining the chronic inflammation.	15491417
Inflammation, Arthritis	Altered Intercellular Communication	In recent-onset arthritis or disk-related lumbosciatic syndrome, Sigma ESR seemed to be a more reliable marker of inflammation than the Westergren ESR and C-reactive protein.	15491977
Inflammation, Obesity, Abdominal, Hypertension, CTCAE	Altered Intercellular Communication	Inflammation, abdominal obesity, and smoking as predictors of hypertension.	15492131
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Development of hypertension has been linked to chronic low-grade inflammation.	15492131
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	However, it is not known whether this connection is mediated by features of the metabolic syndrome or smoking, or their changes, which themselves have been linked to inflammation.	15492131
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Cigarette smoking was also associated with development of hypertension independently of inflammation and other confounders.	15492131
Inflammation, Hypertension, CTCAE, Metabolic Syndrome X	Altered Intercellular Communication	Hypertension is preceded by low-grade chronic inflammation in middle-aged white men independently of smoking or features of the metabolic syndrome.	15492131
Inflammation	Altered Intercellular Communication	Chronic inflammation is a characteristic feature of aging, and the relationship between cellular senescence and inflammation, although extensively studied, is not well understood.	15492272
Inflammation	Altered Intercellular Communication	Understanding the relationship between hPNPase(old-35) and inflammation and aging provides a unique opportunity to mechanistically comprehend and potentially intervene in these physiologically important processes.	15492272
Inflammation, Thrombosis	Altered Intercellular Communication	In conclusion, apoB is more closely associated with central adiposity, insulin resistance, thrombosis, and inflammation than NHDLC.	15492304
Stomatitis, Denture	Altered Intercellular Communication	Denture stomatitis (DS) is a common inflammatory condition that affects denture wearers.	15493034
Inflammation, Ulcer, Stomatitis, Cheilitis, Hyperplasia	Altered Intercellular Communication	Denture-related lesions (stomatitis, hyperplasia, ulcers, inflammation and angular cheilitis) composed 8.4 percent and tobacco-related lesions (smokeless tobacco-related and nicotinic stomatitis) composed 4.7 percent of all lesions.	15493392
Inflammation, Fibrosis Assessment, Endometriosis	Altered Intercellular Communication	Mast cells had previously been reported to be increased at sites of endometriosis, and tryptase may contribute to the fibrosis and inflammation characterizing endometriosis.	15494048
Inflammation, Fibrosis Assessment, Endometriosis	Altered Intercellular Communication	CRH and Ucn may activate mast cells and contribute to the fibrosis and inflammation in endometriosis.	15494048
Inflammation, Ischemic stroke, Carotid Artery Thrombosis, Carotid Atherosclerosis	Altered Intercellular Communication	These results demonstrate a major role of carotid thrombosis and inflammation in ischemic stroke in patients affected by carotid atherosclerotic disease.	15494582
Inflammation, Ulcerative Colitis, Colitis	Altered Intercellular Communication	These results indicate that (i) the proinflammatory moiety IL-1sRI is a systemic marker of inflammation and activity in CD and (ii) local shedding of the functional antagonist IL-1sRII may dampen colonic inflammation in CD, but not in UC.	15498044
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Acute coronary syndromes (ACS) are associated with inflammation resulting from monocyte activation.	15498050
Inflammation, Bell Palsy, Facial paralysis	Altered Intercellular Communication	Bell's palsy involves acute facial paralysis due to inflammation of the facial nerve.	15498373
Occluded, Inflammatory abnormality of the eye, Necrosis of retina	Altered Intercellular Communication	It is characterized by substantial ocular inflammation with progressive retinal necrosis, occlusive vasculitis and sometimes extraocular features.	15499278
Inflammation, Hemorrhage, Glaucoma, CTCAE	Altered Intercellular Communication	Abnormality of lens haptics position, hemorrhage and persistent inflammation were also play a role in secondary glaucoma.	15500765
Inflammation, Data types - Address	Altered Intercellular Communication	The identification of activated microglia within neuritic plaques, coupled with the presence of numerous inflammatory proteins, suggests that inflammation is an integral part of the pathogenetic process in AD.	15501026
Refractory anemias, Brown Tendon Sheath Syndrome, Tenosynovitis	Altered Intercellular Communication	The DM always leads to OMM inflammation, whereas the RA particularly leads to tenosynovitis of the superior oblique muscle referred to as the Brown syndrome.	15501353
Inflammatory abnormality of the eye, Corneal edema	Altered Intercellular Communication	Our examination disclosed bilateral corneal edema without ocular inflammation.	15502485
Inflammation, Superficial ulcer, Eczema	Altered Intercellular Communication	An improvement of eyelid inflammation was observed while eczematous skin lesions and erosions were resolved within 15 days.	15502487
Inflammation, Endothelial dysfunction, diabetic	Altered Intercellular Communication	Moderate alcohol intake and markers of inflammation and endothelial dysfunction among diabetic men.	15502925
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Type 2 diabetes mellitus is characterised by heightened inflammation and endothelial dysfunction.	15502925
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	It remains to be determined whether there is an association between alcohol and inflammation in individuals with diabetes.	15502925
Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Moderate alcohol intake may have a beneficial effect on markers of inflammation and endothelial dysfunction in type 2 diabetic patients.	15502925
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Pathologic results were foreign body reaction in 20 patients, chronic inflammation in eight, and fibrosis in two.	15503010
Inflammation, Neoplasms	Altered Intercellular Communication	Histological workup yielded the diagnosis of a markedly calcified choroid plexus with no indication of neoplasia or inflammation.	15503189
Inflammation, Microabscess	Altered Intercellular Communication	Histology of several colon biopsies revealed marked acute inflammation with microabscess formation of the polyps and the adjacent mucosa.	15504066
Cap polyposis, polyps, Acute inflammation	Altered Intercellular Communication	The histologic features of the resected mass showed giant polyps with acute inflammation diagnostic of giant inflammatory polyposis.	15504066
Inflammation, Endothelial dysfunction, atherosclerotic	Altered Intercellular Communication	The atherosclerotic process is an ongoing dynamic and progressive state arising from endothelial dysfunction and inflammation.	15504106
Cancer-related fatigue, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic renal failure (CRF) provokes derangement in various hormonal regulations of food intake and energy expenditure.	15504146
Inflammation, Lymphoma	Altered Intercellular Communication	Distinct pattern of gene expression in pyothorax-associated lymphoma (PAL), a lymphoma developing in long-standing inflammation.	15504251
Inflammation	Altered Intercellular Communication	The prevalence of chronic inflammation is high in dialysis patients.	15504945
Inflammation	Altered Intercellular Communication	Moreover, it is associated with an increased mortality risk, yet the origin of chronic inflammation in dialysis patients remains unclear.	15504945
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Low-density lipoprotein triglycerides associated with low-grade systemic inflammation, adhesion molecules, and angiographic coronary artery disease: the Ludwigshafen Risk and Cardiovascular Health study.	15505088
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Markers of systemic inflammation and LDL cholesterol (LDL-C) have been considered independent risk factors of coronary artery disease (CAD).	15505088
Inflammation, Vascular System Injuries	Altered Intercellular Communication	We examined whether alterations of LDL metabolism not reflected by LDL-C were associated with low-grade inflammation, vascular injury, and CAD.	15505088
Inflammation, Blood Vessel	Altered Intercellular Communication	Alterations of LDL metabolism characterized by high LDL-TG are related to CAD, systemic low-grade inflammation, and vascular damage.	15505088
Inflammation, Atherosclerosis	Altered Intercellular Communication	Arterial neovascularization and inflammation in vulnerable patients: early and late signs of symptomatic atherosclerosis.	15505090
Inflammation, Thrombosis, Rupture	Altered Intercellular Communication	Inflammation and pathological neovascularization are thought to precipitate plaque rupture or erosion, both causes of arterial thrombosis and cardiovascular events.	15505090
Arteritis, Atherosclerosis	Altered Intercellular Communication	We tested the hypothesis that arterial inflammation and angiogenic events are increased throughout the arterial tree in vulnerable patients, ie, in patients who suffered from cardiovascular events, compared with patients who never suffered from complications of atherosclerosis.	15505090
Axonal degeneration, Inflammation	Altered Intercellular Communication	Sural nerve biopsies showed prominent axonal degeneration and perivascular inflammation.	15505166
Inflammation	Altered Intercellular Communication	Inflammation and altered immunity may play a role in the pathogenesis, but further study is needed.	15505166
Pancreatitis, Necrosis	Altered Intercellular Communication	The modified index included a simplified assessment of pancreatic inflammation and necrosis as well as an assessment of extrapancreatic complications.	15505289
Inflammation, Appendix Epiploica	Altered Intercellular Communication	All 50 patients with acute epiploic appendagitis had a central fatty core surrounded by inflammation.	15505294
vascular inflammations, Erectile dysfunction	Altered Intercellular Communication	We evaluated associations between erectile function, endothelial function and markers of systemic vascular inflammation in 80 obese men, aged 35-55 yr, divided into two equal groups according to the presence/absence of erectile dysfunction.	15505991
Retinal Neovascularization, Inflammatory abnormality of the eye	Altered Intercellular Communication	A 50-year-old man with a history of recurrent relapses of ocular inflammation despite immunosuppressive therapy developed retinal neovascularization near the optic disk.	15506610
Inflammation, Endothelial dysfunction, Obesity	Altered Intercellular Communication	Metabolic alterations such as insulin resistance are thought to underlie the endothelial dysfunction and low grade inflammation found in morbid obesity.	15507518
Inflammation, Obesity	Altered Intercellular Communication	S(I) and adiposity appear to play roles in obesity-related, low grade inflammation that contribute to the endothelial dysfunction observed in morbid obesity.	15507518
Inflammation, Dental Plaque, Healthcare Encounters Domain, Atherosclerosis	Altered Intercellular Communication	Complex plaques of both A and S patients have activation signs for chronic inflammation, phagocytosis, and atheromatosis: all three of these in HE plaque subtypes, and only for atheromatosis in HO plaques.	15507852
Inflammation	Altered Intercellular Communication	The results suggest that anti-TNF treatment with infliximab not only decreases activity of inflammation but also may slow down bone turn-over.	15508789
Inflammation, Glucose Intolerance (disease), Acute myocardial infarction, Diabetes Mellitus	Altered Intercellular Communication	Inflammation, insulin resistance, and glucose intolerance in acute myocardial infarction patients without a previous diagnosis of diabetes mellitus.	15509644
Inflammation, Acute myocardial infarction, Diabetes Mellitus	Altered Intercellular Communication	We examined the prevalence of impaired glucose metabolism and its association with inflammation and insulin resistance (IR) in acute myocardial infarction (AMI) patients without a previous diagnosis of diabetes.	15509644
Inflammation, Congenital Abnormality	Altered Intercellular Communication	These glycometabolic abnormalities are associated with inflammation, IR, and serum adiponectin levels.	15509644
Inflammatory abnormality of the eye	Altered Intercellular Communication	The encapsulated filtering blebs occurred mainly in patients after previous ocular surgery, in eyes with episodes of earlier ocular inflammation and in patients treated with many antiglaucoma drops.	15510490
Inflammation, Empyema	Altered Intercellular Communication	Pleuropneumonectomy, which has been reported to be associated with high mortality and morbidity, is performed when the pleural space is completely obliterated due to previous inflammation or when preoperative empyema is complicated.	15510817
Sepsis, Multiple Organ Failure	Altered Intercellular Communication	He received hormonal replacement and chemotherapy, but he succumbed to his disease because of sepsis and multi-organ failure a few days post diagnosis.	15512826
Inflammation, Fibrosis Assessment, Liver Cirrhosis	Altered Intercellular Communication	However, mild inflammation and fibrosis was observed, grade 1-2 (n = 17), stage I-II (n = 13) and none had cirrhosis.	15513385
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	The theoretical advantages of smaller scleral, conjunctival incision, reduced stimuli to wound healing, and inflammation, could improve long-term IOP control in patients with glaucoma.	15513436
Inflammation, Glomus tympanicum	Altered Intercellular Communication	Four cases who showed inactive inflammation and had an adequate tissue layer to protect the electrode array underwent a single-stage technique, although two of them showed dry tympanic membrane perforation.	15513546
Inflammation, Chronic otitis	Altered Intercellular Communication	Complete eradication of inflammation and the securing of a strong protective soft tissue layer over the electrode are prerequisites for cochlear implantation in ears with chronic otitis media.	15513546
Inflammation, Abnormal degeneration	Altered Intercellular Communication	Heel fat pad inflammation and degeneration have been frequently proved to cause talalgia.	15513682
Inflammation	Altered Intercellular Communication	Dogs exposed to severe air pollution exhibit chronic inflammation and acceleration of Alzheimer's-like pathology, suggesting that the brain is adversely affected by pollutants.	15513908
Inflammation	Altered Intercellular Communication	We investigated whether residency in cities with high levels of air pollution is associated with human brain inflammation.	15513908
Inflammation, "Alzheimers Disease", physiopathological	Altered Intercellular Communication	These findings suggest that exposure to severe air pollution is associated with brain inflammation and Abeta42 accumulation, two causes of neuronal dysfunction that precede the appearance of neuritic plaques and neurofibrillary tangles, hallmarks of Alzheimer's disease.	15513908
vascular inflammations, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Endothelial dysfunction, Cardiovascular Diseases	Altered Intercellular Communication	Alpha-linolenic acid (ALA) reduces cardiovascular disease (CVD) risk, possibly by favorably changing vascular inflammation and endothelial dysfunction.	15514264
Inflammation, Iron deficiency anemia	Altered Intercellular Communication	The serum transferrin receptor (sTfR) is a sensitive indicator of iron-deficiency erythropoiesis that is not affected by inflammation.	15514585
Inflammation, Neoplasms	Altered Intercellular Communication	sTfR was negatively correlated with log ferritin ( r = -.422, P < .05) but did not correlate with tissue inflammation, tumor stage, or acute-phase proteins.	15514585
Intraocular inflammation, Uveitis	Altered Intercellular Communication	In two cases uveitis was bilateral while other two patients developed unilateral intraocular inflammation.	15515319
Intraocular inflammation	Altered Intercellular Communication	In all patients gradual, total regression of intraocular inflammation with the improvement of visual acuity in 3 cases were noted.	15515319
Orbital Pseudotumor	Altered Intercellular Communication	The etiology of nonspecific orbital inflammation remains still unknown.	15515323
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Few studies, however, have examined local biochemical measures of periodontal inflammation in patients with type 2 diabetes.	15515334
Endometriosis	Altered Intercellular Communication	Hormonal and anatomical changes associated with menstruation and pregnancy may affect the rate of laparoscopically confirmed endometriosis.	15516386
Pneumonitis	Altered Intercellular Communication	Within the alveolar compartment, similar disturbances have been described during pulmonary inflammation.	15516673
Inflammation, Cavitation (process), Trauma, Nervous System, Necrosis	Altered Intercellular Communication	Key histologic features of the proposed classification are as follows: (1) phase of acute neuronal injury (11 cases studied), age 1-2 days, characterized by the presence of neuronal changes, and spongiosis of the neuropil and absence of neuronal ferrugination, chronic inflammation, macrophages, neo-vascularization and cavitation; (2) phase of organization subdivided into: (a) phase of acute inflammation (31 cases), age 3-37 days, characterized by coagulative necrosis, and frequent acute inflammation, and (b) phase of chronic inflammation (57 cases), age 10 days-53 years, characterized by the presence or absence of coagulative necrosis, neuronal injury, red neurons, macrophages, mononuclear inflammatory cells, perivascular cuffing, cavitation, gliosis, spheroids; absence of neutrophils; and (3) phase of resorption (38 cases), age 26 days-23 years, characterized by absence of an inflammatory response.	15517310
Pseudocyst, Pancreatitis, Calculi	Altered Intercellular Communication	Histopathological criteria and clinical features were recorded in pancreatic resection specimens from 53 patients who were found to have chronic pancreatitis lacking pseudocysts, calculi, irregular duct dilatations, pancreas divisum and/or duodenal wall inflammation.	15517359
Inflammation	Altered Intercellular Communication	The severity of the chronic inflammation was graded, and the activity of the acute inflammatory component and the granulocytic epithelial lesion (GEL) were determined.	15517359
Pseudocyst, Pancreatitis, Calculi, Pancreas divisum	Altered Intercellular Communication	These changes were absent in 147 pancreatic specimens that showed chronic pancreatitis associated with pseudocysts, calculi, pancreas divisum and/or duodenal wall inflammation.	15517359
Inflammation, Chlamydia	Altered Intercellular Communication	It is unknown whether Chlamydia initiate or lead to the inflammation of the already existent disease process.	15518420
Inflammation, Fibrosis Assessment, Aortic Valve Stenosis	Altered Intercellular Communication	Chronic inflammation and fibrosis are involved in the pathogenesis of aortic stenosis (AS), but the detailed molecular mechanisms of this atherosclerosis-like process remain obscure.	15519020
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Angiotensin II, a powerful mediator of inflammation and fibrosis, may participate in AS progression.	15519020
Inflammation	Altered Intercellular Communication	These novel findings, implicating chronic inflammation and an increased expression of local Ang II-forming systems, suggest that therapeutic interventions aiming at inhibiting these processes may slow AS progression.	15519020
Hypersomnia, Encephalomyelitis, Acute Disseminated	Altered Intercellular Communication	Decreased hypothalamic hypocretin neurotransmission may be involved in this symptomatic case of hypersomnia associated with acute disseminated encephalomyelitis.	15519122
Fibrosis Assessment, Fatty degeneration, Balloon Dilatation	Altered Intercellular Communication	Comparing the histological findings of cases and controls we found a similar severity of steatosis and fibrosis, with a greater prevalence of ballooning degeneration and glycogenated-nuclei rather than lobular-inflammation.	15519647
Inflammation, Asthma, Bronchoconstriction	Altered Intercellular Communication	Optimal therapy for many patients with persistent asthma requires control of both main components of this disease: inflammation and bronchoconstriction.	15521371
Inflammation, Asthma, physiopathological	Altered Intercellular Communication	In patients symptomatic while taking short-acting beta2-agonists alone, initial maintenance treatment of the 2 main components of asthma, inflammation and smooth muscle dysfunction, with fluticasone propionate and salmeterol, 100 and 50 microg, administered via the Diskus results in greater improvements in overall asthma control compared with treatment of either component alone.	15521371
Inflammation, Ulceration, CTCAE, Atrophic, Granulation finding	Altered Intercellular Communication	The type C pattern with a severe inflammation in lamina propria together with severe atrophy of villi, sometimes with ulceration and granulation tissue, was observed by the two pathologists from one centre in 15 of 45 (33.3%) patients and in 11 (24.4%) of 45 by the third pathologist, respectively.	15521942
Inflammation, Lymphocytic infiltration	Altered Intercellular Communication	Histopathologic examination demonstrated active inflammation with lymphocytic infiltration of the choroid.	15522374
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	To compare a single intraoperative sub-Tenon's capsule triamcinolone acetonide injection with steroid drops in the treatment of ocular inflammation after cataract surgery.	15522378
Intraocular inflammation	Altered Intercellular Communication	Triamcinolone was shown to have anti-inflammatory efficacy clinically equivalent to conventional 1% prednisolone eyedrops in reducing intraocular inflammation, as measured by clinical methods.	15522378
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Studies on the role of inflammation in cardiovascular disease focus on surrogate markers like plasma levels of C-reactive protein or interleukins that are affected by several factors.	15522960
Communicable Diseases, Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Occasionally, pneumoparotid can be recurrent and lead to inflammation and infection of the parotid or subcutaneous emphysema.	15523461
Necrotizing granulomatous inflammation, Granuloma	Altered Intercellular Communication	The pathological findings were caseous granuloma with positive acid-fast bacilli (AFB) in 15 cases, caseous granuloma with negative AFB in 3 cases, and chronic granulomatous inflammation with negative AFB in 5 cases.	15523462
Levator syndrome, Inflammation, Tendinitis, Muscle Spasticity	Altered Intercellular Communication	Two theories have been reported for the pathophysiology of levator ani syndrome: the spastic cycle hypothesis and the local inflammation (Tendinitis) hypothesis.	15526112
Inflammation, Ischemic stroke, diabetic	Altered Intercellular Communication	IgG anti-cardiolipin antibodies-markers of inflammation in diabetic patients with ischemic stroke.	15526511
Pathology	Altered Intercellular Communication	IgG aCL indicate inflammatory conditions in these pathologies.	15526511
Inflammation, Hypercholesterolemia, Atherosclerosis	Altered Intercellular Communication	Recent publications have reanimated the point of view that there exist links between atherosclerosis--inflammation and hypercholesterolemia.	15526541
Inflammation, Ischemic stroke	Altered Intercellular Communication	Study of some markers of inflammation in atherothrombotic pathogenesis of acute ischemic stroke.	15526546
Inflammation, Cerebral Ischemia	Altered Intercellular Communication	Recent researches focused on the study of the role of the inflammation in the atherothrombotic pathogenesis of the acute cerebral ischemia.	15526546
Inflammation, In-Stent Restenosis Indicator	Altered Intercellular Communication	Pathogen burden, inflammation, proliferation and apoptosis in human in-stent restenosis.	15528935
Cessation of life, Inflammation	Altered Intercellular Communication	Among others, inflammation, immune reactions, deregulated cell death and growth have been suggested.	15528935
Inflammation, Hyperplasia	Altered Intercellular Communication	In summary, human ISR at the time of clinical presentation is characterized by low frequency of pathogen burden and inflammation, but pronounced hypercellularity, low apoptosis and absence of proliferation.	15528935
Inflammation, Leukocytosis, Anemia, Cholestasis, Kidney Failure	Altered Intercellular Communication	Laboratory examinations revealed leukocytosis, anemia, elevation of cholestasis and inflammation parameters as well as renal failure.	15529241
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Antibodies directed toward citrullinated proteins (e.g., anti-cyclic citrullinated peptide antibodies) are highly specific for rheumatoid arthritis (RA) and are produced locally at the site of inflammation.	15529392
Refractory anemias	Altered Intercellular Communication	The presence of citrullinated proteins in the inflamed synovium is not specific for RA, but rather, it may be an inflammation-associated phenomenon.	15529392
Sepsis, Inflammation	Altered Intercellular Communication	Some mediators of inflammation are associated with sepsis, involving nervous system.	15529589
Pharyngolaryngeal Pain, Tuberculosis, Vasculitis of large artery, Sarcoidosis, Granulomatous inflammation, Mycoses, Hodgkin Disease	Altered Intercellular Communication	We report the case of a 29 years old man who developed a pharyngolaryngeal tumor with clinically benign evolution, histologically showing granulomatous inflammation and small vessel vasculitis, with no signs of: tuberculosis, sarcoidosis, fungal disease, Hodgkin's disease or foreign body aspiration.	15529590
Granulomatous inflammation, Neoplasms, Vasculitis, CTCAE, Granulomatous disorder	Altered Intercellular Communication	The finding of a pharyngolaryngeal tumor with granulomatous inflammation and vasculitis, in the context of p-ANCA positivity and without any evidence for another systemic granulomatous disease, suggested the diagnosis of limited WD.	15529590
Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation is considered a crucial step in the pathogenesis of acute coronary syndromes (ACS).	15529598
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Our study looked at the links between inflammation and the prothrombotic factors present in patients with ACS without ST elevation.	15529598
Inflammation, Thrombosis	Altered Intercellular Communication	When comparing the 1st with the 4th CRP quartiles, we noted that important inflammation (4th quartile) was associated with higher factor von Willebrand (141.3 vs 108.9%, p<0.05), factor 5 (127.5% vs 88%, p<0.01), factor 8 (121.5 vs 117.1%, p=0.04), lower AT III (101.6 vs 118.2%, p<0.05), lower protein C and S. The associations did not keep for PAI-I or D-dimers, which might be associated with the lack of sensibility of fibrinolysis markers in the early period after thrombosis.	15529598
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Inflammation, as quantified by CRP, appears to be associated with a significant prothrombotic status and endothelial dysfunction (as reflected by high von Willebrand factor).	15529598
Inflammation, Pituitary Adenoma	Altered Intercellular Communication	Granulomatous inflammation of the pituitary gland is a rare disease that mimics non-functioning pituitary adenoma.	15530282
Inflammation, Soft Tissue Infection, Fever, CTCAE, Cellulitis	Altered Intercellular Communication	Cellulitis is a rare and severe soft-tissue infection characterized by acute, diffuse, spreading inflammation, often associated with systemic symptoms such as malaise and fever.	15530310
Inflammation, Albuminuria	Altered Intercellular Communication	Recent work has highlighted the importance of markers of inflammation, such as C-reactive protein (CRP), homocysteine and albuminuria as predictors of cardiovascular risk in urban westernized settings.	15530919
Inflammation	Altered Intercellular Communication	Increased IMT (> or =0.72 mm) was associated with increased CRP concentrations over a range that suggests infection/inflammation may be important determinants of cardiovascular risk in this setting.	15530919
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Serotonergic neurotransmitter system has been implicated in the pathogenesis of Alzheimer's disease (AD).	15531082
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is characterized by a long-standing chronic inflammation of the bowel with intermittent periods of exacerbation and remission.	15531481
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In UC patients without glucocorticoid treatment, Ucn1-positive cells and plasma cells increased in proportion to the severity of inflammation (P < 0.0001).	15531481
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	CXC chemokine ligand 10 (CXCL10), an interferon-gamma-inducible chemokine associated with Th1-mediated immune responses, has been proposed as a marker of inflammation in autoimmune diseases.	15531503
Coronary heart disease	Altered Intercellular Communication	The levels of bilirubin may be related to an inflammatory condition in patients with coronary heart disease.	15532302
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	A lower salivary gland inflammatory focus score and higher salivary flow rate in CD + SS than in SS suggests that a gluten-free diet treatment may alleviate autoimmune inflammation.	15533207
Inflammation, Eosinophilic granulomatosis with polyangiitis	Altered Intercellular Communication	Multiple granulomatous inflammation in the minor salivary glands: a proposed new entity, allergic granulomatous sialadenitis.	15533228
Granulomatous inflammation	Altered Intercellular Communication	We report a patient who presented with multiple small submucosal nodules with granulomatous inflammation in the minor salivary glands of the oral cavity.	15533228
Inflammation, Toxic effect	Altered Intercellular Communication	Earlier (18)F-FDG PET, such as day 1 after chemotherapy, may be affected by inflammation or chemotoxicity in addition to chemotherapeutic effects, but the ways in which uptake is changed are as yet unclear.	15534052
Inflammation	Altered Intercellular Communication	Three patients had lumbar sensory rootlet biopsies that showed thickened rootlets, decreased density of large myelinated fibers, segmental demyelination, onion-bulb formation, and endoneurial inflammation.	15534252
Inflammation	Altered Intercellular Communication	However ther is an association between apoptosis and activity of inflammation in patients with chronic HBV infection.	15534924
Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Dysfunction in various parts of immune defence, such as immune response, immune complex clearance, and inflammation, has an impact on pathogenesis in systemic lupus erythematosus (SLE).	15535834
Inflammation, Impaired cognition, Metabolic Syndrome X	Altered Intercellular Communication	The metabolic syndrome, inflammation, and risk of cognitive decline.	15536110
Inflammation, Impaired cognition, Metabolic Syndrome X	Altered Intercellular Communication	To determine if the metabolic syndrome is a risk factor for cognitive decline and if this association is modified by inflammation.	15536110
Inflammation, Impaired cognition, Metabolic Syndrome X	Altered Intercellular Communication	There was a statistically significant interaction with inflammation and the metabolic syndrome (P = .03) on cognitive impairment.	15536110
Inflammation, Impaired cognition, Metabolic Syndrome X	Altered Intercellular Communication	After stratifying for inflammation, those with the metabolic syndrome and high inflammation (n = 348) had an increased likelihood of cognitive impairment compared with those without the metabolic syndrome (multivariate adjusted RR, 1.66; 95% CI, 1.19-2.32).	15536110
Inflammation, Impaired health, Metabolic Syndrome X	Altered Intercellular Communication	Those with the metabolic syndrome and low inflammation (n = 668) did not exhibit an increased likelihood of impairment (multivariate adjusted RR, 1.08; 95% CI, 0.89-1.30).	15536110
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Stratified multivariate random-effects models demonstrated that participants with the metabolic syndrome and high inflammation had greater 4-year decline on 3MS (P = .04) compared with those without the metabolic syndrome, whereas those with the metabolic syndrome and low inflammation did not (P = .44).	15536110
Inflammation, Impaired cognition, Metabolic Syndrome X	Altered Intercellular Communication	These findings support the hypothesis that the metabolic syndrome contributes to cognitive impairment in elders, but primarily in those with high level of inflammation.	15536110
Inflammation, Asthma, MS4A2 wt Allele	Altered Intercellular Communication	The relationship between atopy, asthma, and eosinophilic inflammation is less clear in early childhood than later in life.	15536407
Inflammation, Asthma, MS4A2 wt Allele	Altered Intercellular Communication	The higher serum ECP levels seen in 6-year-old children with current asthma and more severe atopy suggest that atopy and eosinophilic inflammation are important in driving this clinical phenotype and that this might represent asthma that persists.	15536407
Airway structure, Respiratory Hypersensitivity, Pulmonary Eosinophilia, Bronchitis	Altered Intercellular Communication	Nonasthmatic eosinophilic bronchitis is a condition characterized by the presence of eosinophilic airway inflammation in the absence of airflow obstruction or airway hyperresponsiveness.	15536417
Airway structure, Asthma, Bronchial Hyperreactivity	Altered Intercellular Communication	In asthma, the T H 2-type cytokine IL-13 has been implicated in the development of airway inflammation and hyperresponsiveness.	15536417
Communicable Diseases, Inflammation	Altered Intercellular Communication	A catheter-related infection (CRI) was defined as a colonized catheter with local signs of inflammation.	15537696
Inflammation	Altered Intercellular Communication	Excoriations and mild inflammation were noted around all affected areas (Figure).	15538091
Inflammation, Edema	Altered Intercellular Communication	Similarly, patchy increases in free water content suggested a pattern of intramuscular edema or inflammation.	15538561
Inflammation, Edema	Altered Intercellular Communication	While fibrofatty changes have been described in DMD, this study further defines differential involvement and additionally suggests widespread edema or inflammation.	15538561
Neuronal degeneration, Deficit	Altered Intercellular Communication	Such mutations are predicted to alter the three-dimensional structure of the prohormone, which accumulates in the cell body, ultimately leading to neuronal degeneration and hormonal deficit.	15538939
Refractory anemias, Inflammation, Rheumatoid Arthritis, Destruction (action)	Altered Intercellular Communication	Monocytes/macrophages have an important and versatile role in joint inflammation and destruction in rheumatoid arthritis (RA).	15539412
Inflammation, Pseudomembrane	Altered Intercellular Communication	Twenty-six of 67 patients (39 percent) underwent colonoscopy; all 26 were found to have severe inflammation or pseudomembranes.	15540290
Inflammation	Altered Intercellular Communication	Cytotoxic lymphocyte antigen-4 (CTLA-4) plays an important role in regulating T cell activation, and may help to limit T cell response under conditions of inflammation.	15540511
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation has been implicated in the pathogenesis of cardiovascular diseases.	15541240
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	C-reactive protein (CRP), a marker of systemic inflammation, predicts the risk of coronary events and stroke.	15541240
Inflammation, Familial cold urticaria	Altered Intercellular Communication	Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist.	15541451
Endometriosis, Inflammation, Cyst	Altered Intercellular Communication	However, the FDG uptake in this particular case of endometriosis seems to have been due to inflammation rather than to a cyst.	15541863
Inflammation, Pouchitis, Ulcerative Colitis	Altered Intercellular Communication	In patients with ulcerative colitis this is subject to inflammation and termed pouchitis.	15542518
Inflammation, Pseudopolyposis of colon, Stenosis	Altered Intercellular Communication	Data were collected on post-inflammatory polyps, scarring, strictures, backwash ileitis, a shortened, tubular, or featureless colon, severe inflammation, and normal looking surveillance colonoscopies.	15542520
Inflammation, Pseudopolyposis of colon, Stenosis	Altered Intercellular Communication	On univariate analysis, cases were significantly more likely to have post-inflammatory polyps (odds ratio (OR) 2.14 (95% confidence interval 1.24-3.70)), strictures (OR 4.22; 1.08-15.54), shortened colons (OR 10.0; 1.17-85.6), tubular colons (OR 2.03; 1.00-4.08), or segments of severe inflammation (OR 3.38; 1.41-10.13), and less likely to have had a macroscopically normal looking colonoscopy (OR 0.40; 0.21-0.74).	15542520
Inflammation	Altered Intercellular Communication	Activation of the epidermal growth factor receptor by respiratory syncytial virus results in increased inflammation and delayed apoptosis.	15542601
Inflammation, Scleritis, Episcleritis	Altered Intercellular Communication	Of all 103 patients diagnosed with either episcleritis or scleritis, 41 (39.8%) were smoking during treatment of the scleral inflammation.	15543188
Inflammation, Overweight	Altered Intercellular Communication	The aim of this study was to clarify if there is an association between overweight and a state of chronic, low-grade inflammation in adolescents.	15543221
ARCN1 gene, Airway structure	Altered Intercellular Communication	These data show that the small sputum macrophages are a major macrophage population in COPD and that these cells exhibit features of highly active inflammatory cells and may therefore be instrumental in airway inflammation in COPD.	15544629
Vasculitis, Inflammation, Avian Sarcoma Viruses	Altered Intercellular Communication	The anti-neutrophilic cytoplasmatic autoantibody-associated vasculitides (AASV) are diseases of relapsing-remitting inflammation.	15545059
Malignant Peripheral Nerve Sheath Tumor, Acute inflammation	Altered Intercellular Communication	The authors describe a 29-year-old woman with disseminated MPNST who presented with acute right orbital inflammation.	15545132
Coma, Post-Head Injury	Altered Intercellular Communication	Post-traumatic inflammation is connected to monocyte dysfunction characterized by reduced NF-kappaB translocation during the first post-traumatic days.	15545823
Vasculitis	Altered Intercellular Communication	Rapamycin attenuates vascular wall inflammation and progenitor cell promoters after angioplasty.	15546959
Inflammation, Atherosclerosis, Refractory anemias, Rheumatoid Arthritis, Arterial Stiffness	Altered Intercellular Communication	Chronic systemic inflammation may contribute to accelerated atherosclerosis and increased arterial stiffness in patients with rheumatoid arthritis (RA).	15547080
Chronic lymphocytic inflammation, Granuloma	Altered Intercellular Communication	No examples of granulomas, chronic lymphoplasmacytic inflammation, or granulation tissue formation were seen, with only rare foreign-body giant cells present.	15547122
Aneurysm, Inflammation	Altered Intercellular Communication	The patient underwent surgical excision of the aneurysm, during which marked periaortic inflammation phenomena, complete absence of the posterior aortic wall for a length of 5-6 cm, and the exposure of the correspondent vertebral bodies were observed.	15547658
Aneurysmal, Thrombus, Inflammation	Altered Intercellular Communication	Histopathologic examination of the aneurysmal tissue showed atheromatous and thrombotic aspects and confirmed strong signs of inflammation.	15547658
Hepatitis C, Hepatitis	Altered Intercellular Communication	The CCR5Delta32 allele is associated with reduced liver inflammation in hepatitis C virus infection.	15548261
Inflammation, Pain Distress Question, Intervertebral Disk Displacement	Altered Intercellular Communication	Inflammation and irritation of the nerve roots has been indicated as an important factor in the pain associated with symptomatic disc herniations.	15549486
Inflammation, Endothelium, COL4A2 wt Allele, Cerebral Hemorrhage	Altered Intercellular Communication	To investigate whether molecular markers of inflammation and endothelial injury are associated with early growth of intracerebral hemorrhage (ICH).	15550687
Inflammation, Arthritis, septic, effusion	Altered Intercellular Communication	This study examined the laboratory variables of inflammation and the levels of gelatinase A and B (matrix metalloproteinases-2 and -9) in 75 effusions from the knees of 37 patients with inflammatory arthritis and compared them with effusions of septic and aseptic arthritis.	15552155
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Time course of systemic markers of inflammation in patients presenting with acute coronary syndromes.	15552272
Acute Coronary Syndrome, Rupture	Altered Intercellular Communication	Inflammation within coronary plaques may cause an acute coronary syndrome by promoting rupture and erosion.	15552272
Inflammation, Dental Plaque, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	In the long-term time course these markers of inflammation and plaque remodeling slightly decreased in ACS patients.	15552272
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	This study demonstrates the importance of a systemic inflammatory condition in patients with ACS, in whom markers of inflammation are increased as compared to controls.	15552272
vascular inflammations, GDC AJCC Clinical Stage Terminology, Atherosclerosis	Altered Intercellular Communication	During long-term follow-up the pro-inflammatory activity remains elevated in ACS patients, supporting the concept of a systemic rather than a local vascular inflammation contributing to the development of atherosclerosis.	15552272
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	This study demonstrates the importance of a systemic inflammatory condition in patients with ACS, in whom markers of inflammation are increased as compared to controls.	15552272
Inflammation, Leukemia, Myelocytic, Acute	Altered Intercellular Communication	We report a case of cytarabine induced inflammation of seborrheic keratoses mimicking a vesicular eruption in 53-year-old man with acute myelogenous leukemia.	15552612
helium, Hepatic Encephalopathy	Altered Intercellular Communication	It has been suggested that alterations of GABAergic neurotransmission are implicated in the pathophysiology of hepatic encephalopathy (HE).	15554420
Inflammation, Hyperhomocysteinemia, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	No effect of folic acid on markers of endothelial dysfunction or inflammation in patients with type 2 diabetes mellitus and mild hyperhomocysteinaemia.	15554600
Chronic inflammation, Endothelial dysfunction	Altered Intercellular Communication	Homocysteine may exert its detrimental effects through induction of endothelial dysfunction and/or chronic inflammation.	15554600
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Hyperhomocysteinemia, Endothelial dysfunction	Altered Intercellular Communication	The data indicate that, in this group of patients with type 2 diabetes mellitus and mild hyperhomocysteinaemia, lowering homocysteine with folic acid for six months does not improve biochemical markers of endothelial dysfunction or low-grade inflammation.	15554600
Inflammation, Pneumonia, Community acquired pneumonia	Altered Intercellular Communication	We hypothesize that hydrocortisone infusion in severe community-acquired pneumonia attenuates systemic inflammation and leads to earlier resolution of pneumonia and a reduction in sepsis-related complications.	15557131
Hepatitis	Altered Intercellular Communication	However, the liver and bowel inflammation are rarely concomitant, and PSC can develop in patients whose colons have been removed previously.	15557349
Inflammatory Bowel Diseases	Altered Intercellular Communication	We hypothesized that PSC is mediated by long-lived memory T cells originally activated in the gut, but able to mediate extra-intestinal inflammation in the absence of active IBD (Grant, A.J., P.F.	15557349
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The markers of endothelial cells do not depend on the degree of inflammation and fibrosis.	15557702
HD Term Type, Inflammation, Atherosclerosis	Altered Intercellular Communication	This immediate and multi-potent action of the statins could be clinically useful in acute atherosclerosis complications or in the treatment of chronic inflammation in HD patients.	15557765
APP gene, Inflammation, Aortic Aneurysm, Abdominal, Atherosclerosis	Altered Intercellular Communication	Inflammation is involved in the pathogenesis of atherosclerosis and abdominal aortic aneurysm (AAA), and chemokines are mediators of the inflammatory process.	15557916
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	The increased monocytic expression of important surface receptors together with elevated serum inflammation markers supports the concept of increased inflammation in type 2 diabetes and may be an important factor for the risk of atherosclerosis.	15558232
Inflammation, SLC25A20 gene	Altered Intercellular Communication	Serum concentrations of calcium, phosphorus, iPTH, and inflammation markers do not predict the appearance or progression of CAC.	15558523
Mesothelial cell, Chronic inflammation, Comorbidity	Altered Intercellular Communication	It might include comorbidity, chronic inflammation, or an effect of mesothelial cell mass on peritoneal transport by the production of vasoactive substances.	15559485
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	The inflammation of gastric mucosa with intestine metaplasia is still observed.	15559613
Inflammation, Tooth structure	Altered Intercellular Communication	The teeth were divided into three tooth groups (I-III) reflecting the history of inflammation of the surrounding gingiva (gingival index (GI) scores) over 26 years: (I) teeth with surrounding gingival units scoring a minimum of one site with GI=0 and a maximum of three sites with GI=1, (II) teeth with surrounding gingival units scoring a minimum of one site with GI=1 and a maximum of three sites with GI=2 over the observation periods and (III) teeth with surrounding gingival units always scoring a minimum of GI=2 (bleeding on probing) at all sites over the observation period.	15560816
Tooth structure	Altered Intercellular Communication	Teeth surrounded with inflammation-free gingival tissues were maintained for a tooth age of 51 years, while teeth consistently surrounded with inflamed gingivae yielded a 46-times higher risk to be lost.	15560816
Inflammation, Tooth Loss	Altered Intercellular Communication	This documents the role of gingival inflammation as a risk factor for future tooth loss.	15560816
Inflammation, Asthma, Pneumonitis	Altered Intercellular Communication	Exhaled nitric oxide increases in inflammatory lung conditions (eg, asthma) in proportion to the severity of inflammation, and has been proposed as a marker of pulmonary inflammation during cardiopulmonary bypass.	15561052
Pneumonitis	Altered Intercellular Communication	Changes in the rate of alveolar production of exhaled nitric oxide may be used as a marker of pulmonary inflammation in coronary artery surgery.	15561052
Inflammation, Bronchial-associated lymphoid tissue	Altered Intercellular Communication	In addition, the observation of specific cellular distribution of bronchus-associated lymphoid tissue suggests that chronic antigenic stimulation and /or inflammation in CHP may cause bronchus-associated lymphoid tissue development, which is likely to play an important role in the mucosal immune response of this disease.	15561262
Asthma, Pneumonitis	Altered Intercellular Communication	Distal lung inflammation may be important in asthma pathophysiology.	15563633
Bronchioles	Altered Intercellular Communication	was concordant with increased bronchial and bronchiolar inflammation.	15564507
Inflammation, Refractory anemias, Rheumatoid Arthritis, Anemia, Chronic disease	Altered Intercellular Communication	Anemia of chronic disease (ACD) is a frequent complication of chronic inflammation in rheumatoid arthritis (RA).	15565327
Meningitis, Bacterial, Meningitis	Altered Intercellular Communication	Case report: greater meningeal inflammation in lumbar than in ventricular region in human bacterial meningitis.	15566596
Meningitis	Altered Intercellular Communication	This might suggest a greater extent of meningeal inflammation in the lumbar than in the ventricular region.	15566596
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Endothelial dysfunction and inflammation after percutaneous coronary intervention.	15566916
Inflammation, Thrombosis, Calcinosis, Myxoma	Altered Intercellular Communication	The myxoma did not differ with location or clinical event in terms of pathological scores, such as vascular proliferation, inflammation, cellularity, hyaline, calcification and thrombosis.	15568157
Inflammation, Postoperative intestinal obstruction	Altered Intercellular Communication	TAPP increased the risk of postoperative intestinal obstruction, but other risk factors, especially previous abdominal surgery or inflammation, have greater influence.	15568160
Inflammation	Altered Intercellular Communication	The highest adjusted relative risks (RR) were found in patients with previous admissions for abdominal inflammations or operations.	15568160
Inflammation, Carcinoma, Neoplasms	Altered Intercellular Communication	In 68 carcinomas, tumor type, grade, inflammation and vascular space involvement were determined.	15568401
Duodenum	Altered Intercellular Communication	Stools were repeatedly negative for parasite ova, but duodenal and colonic biopsies demonstrated Schistosoma eggs and eosinophilic granulomatous inflammation.	15569782
Synovial Cyst, Subluxation of atlantoaxial joint, Congenital Abnormality	Altered Intercellular Communication	The authors report a synovial cyst at the C1-C2 junction in a patient with atlantoaxial subluxation without a congenital anomaly or inflammatory conditions.	15570128
Pituitary Apoplexy, Pituitary Adenoma	Altered Intercellular Communication	Pituitary apoplexy is a rare major clinical event with neurological, neuro-ophthalmological, cardiovascular and hormonal consequences, resulting from an acute infarction of pituitary adenoma.	15570437
Hepatobiliary Disorder, Hepatic inflammation, Hepatitis C	Altered Intercellular Communication	The findings from this pilot study suggest that rhIL-11 may be beneficial for patients with hepatic inflammation and advanced liver disease associated with chronic HCV infection.	15571583
Inflammation	Altered Intercellular Communication	Inflammation may be an explanation for this phenomenon.	15571615
Cystic Lesion, Inflammation, Adenocarcinoma of lung (disorder), Bronchioloalveolar Adenocarcinoma	Altered Intercellular Communication	In cystic lesions, particularly those not associated with inflammation, lung adenocarcinoma, particularly bronchioloalveolar cell carcinoma type, should be a diagnostic consideration.	15571644
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Markers of inflammation in patients with coronary artery disease are also associated with glycosylated haemoglobin A1c within the normal range.	15571827
Inflammation, Diabetes Mellitus, Atherosclerosis	Altered Intercellular Communication	Diabetes is a risk factor for atherosclerosis and low-degree inflammation may play a central role in both diseases.	15571827
Inflammation, diabetic	Altered Intercellular Communication	All inflammation markers were altered in a more inflammatory direction in diabetic patients.	15571827
Inflammation, Angina Pectoris	Altered Intercellular Communication	This study was designed to compare the differences in anti-oxLDL titers and isotypes in unstable and stable angina patients and to correlate these results with known markers of active inflammation in CAD.	15571928
Autoimmune Diseases, Inflammation, GDC AJCC Clinical Stage Terminology, Atherosclerosis	Altered Intercellular Communication	The presence of anti-Apo A-1 autoantibodies in patients with ACS highlights an additional link between autoimmunity, inflammation and atherosclerosis.	15571929
Inflammation, Tubular atrophy, Interstitial Fibrosis Assessment	Altered Intercellular Communication	Serum uric acid had independent associations with the presence of tubular atrophy and interstitial fibrosis and inflammation.	15572382
Nephritis, Interstitial, Inflammation, IGA Glomerulonephritis	Altered Intercellular Communication	Serum uric acid may have an independent role in development of tubulointerstitial lesions as well as being associated with inflammation in renal tissue of patients with IgAN.	15572382
Airway structure	Altered Intercellular Communication	Comparison between exhaled and sputum oxidative stress biomarkers in chronic airway inflammation.	15572547
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Both the local and systemic inflammation observed in OSAS induce certain potent pro-inflammatory mediators, which may contribute to the development of cardiovascular consequences.	15572852
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Surgical treatment of patients with OSAS reduces the plasma TNF-alpha levels, thereby ameliorating the systemic inflammation and preventing the development of cardiovascular consequences.	15572852
Inflammation, Obstruction	Altered Intercellular Communication	Interferon gamma-1b (IFN-gamma1b) is a pleiotropic cytokine with immunomodulatory activities that could decrease bacterial burden, inflammation, and obstruction in patients with CF.	15573395
Microalbuminuria, Inflammation	Altered Intercellular Communication	The present study has shown that low-grade inflammation as represented by high sensitivity CRP levels may be significantly related to the presence of microalbuminuria.	15575240
Microalbuminuria, Inflammation	Altered Intercellular Communication	This suggests that microalbuminuria may be a useful marker representing systemic low-grade inflammation as well as being an established cardiovascular risk factor in apparently healthy individuals.	15575240
Inflammatory disease of mucous membrane	Altered Intercellular Communication	This study demonstrated that DL inhibits activation of both eosinophils and mast cells derived from a site of airway mucosal inflammation.	15575935
Thermal injury, Inflammation	Altered Intercellular Communication	During dermal injury and inflammation the serine proteases kallikreins cleave endogenous, multifunctional substrates (kininogens) to form bradykinin and kallidin.	15576327
Inflammation, Tissue injury	Altered Intercellular Communication	A feature of the kinin-B1 receptors is that they show low levels of expression, but are distinctly upregulated following tissue injury and inflammation.	15576327
Inflammation, Experimental Organism Benign Basalioma, Psoriasis, Dermatitis, Atopic	Altered Intercellular Communication	Because recent evidence suggested that kinin-B1 receptors may perform a protective role during inflammation, we investigated the specific occurrence of the kallikrein-kinin components in skin biopsies obtained from normal skin, patients undergoing surgery, basalioma, lichenificated atopic eczema, and psoriasis.	15576327
Inflammation	Altered Intercellular Communication	Within the multiple steps of the inflammatory cascade in wound healing, our results suggest an important regulatory role for kinin-B1 receptors during the first phase of inflammation following injury.	15576327
Craniosynostosis	Altered Intercellular Communication	The anomalous immune and inflammatory responses to ubiquitous fungi may explain the chronicity of airway inflammation in CRS.	15577837
Inflammation, Diverticular Diseases	Altered Intercellular Communication	In diverticular disease, active inflammation determined a less significant increase of subepithelial aggregates harboring a lower proportion of germinal centers.	15578077
Inflammation, Cutis Laxa	Altered Intercellular Communication	Our findings suggest that this clinical behavior is from elastolysis as a result of inflammation.	15578131
Inflammation, Traumatic injury	Altered Intercellular Communication	The presentation of SO in a vitrectomized patient after severe blunt trauma with extended intra-ocular tamponade with PFCL could support the hypothesis that chronic inflammation caused by PFCL could have contributed to the development of SO.	15578285
Inflammation, Cardiovascular system, Malnutrition, Cardiovascular Diseases	Altered Intercellular Communication	In conclusion, a higher REE is associated with increased mortality and cardiovascular death in CAPD patients and is partly related to its close correlations with residual kidney function, cardiovascular disease, inflammation, and malnutrition in these patients.	15579517
Inflammation	Altered Intercellular Communication	Interventions that reduce inflammation might confer significant cardiovascular and renal benefits.	15579522
Inflammation, Adenolymphoma	Altered Intercellular Communication	The histomorphological examination of the surgical specimen showed an intraglandular area of predominantly chronic histiocytic inflammation with foreign body reaction in the intimate neighbourhood of a small, subtotally infarcted Warthin's tumour.	15580331
Infarction, Adenolymphoma, Inflammation, Parotitis	Altered Intercellular Communication	In terms of the possible causes of the severe intraglandular inflammation, all arguments favour a primary infarction of the Warthin's tumour with the release of intraluminal preformed crystals which secondarily induce a massive inflammation with foreign body reaction, corresponding to the clinical presentation of a subacute parotitis.	15580331
Airway structure, Bronchiectasis	Altered Intercellular Communication	It appears that eNO might not reflect the extent of airway inflammation in bronchiectasis.	15581196
ovarian neoplasm, Carcinogenesis, Inflammation	Altered Intercellular Communication	Recent studies of ovarian cancer have suggested a role for inflammation in carcinogenesis.	15581980
Eruptions, Inflammation, Chronic ulcer of lower extremity	Altered Intercellular Communication	These eruptions might be caused by intermittent hemolysis-induced inflammation as a result of the increased osmotic fragility of the erythrocytes and may evolve to chronic leg ulcers later in life.	15583606
Inflammation, Uveitis	Altered Intercellular Communication	We also classified the disease into four groups: uveitis pan, anterior, intermediate, and posterior uveitis, according to the site of inflammation.	15584355
Inflammation, Asthma	Altered Intercellular Communication	Exhaled nitric oxide (ENO) has been shown to be a noninvasive marker of eosinophilic inflammation in asthmatic children.	15584635
Airway structure	Altered Intercellular Communication	Measurement of fractional exhaled nitric oxide (FENO) is a noninvasive, simple, well-tolerated, and reproducible marker of airway inflammation.	15584636
Airway structure	Altered Intercellular Communication	Asthmatic children with normal respiratory function could be affected by airway inflammation.	15584636
Airway structure, Intermittent asthma	Altered Intercellular Communication	We suggest that FENO measurement could represent a good marker of airway inflammation also in naive atopic children with intermittent asthma.	15584636
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	MIF is expressed in advanced atherosclerotic lesions in close correlation with signs of instability, such as mononuclear cell inflammation and neointimal microvessel formation.	15585204
Kidney Failure, Chronic	Altered Intercellular Communication	Impairment of small intestinal protein assimilation in patients with end-stage renal disease: extending the malnutrition-inflammation-atherosclerosis concept.	15585765
Inflammation, Atherosclerosis	Altered Intercellular Communication	Several indexes of nutritional status, inflammation, and atherosclerosis were assessed.	15585765
Communicable Diseases, Helicobacter pylori, Inflammation, Coronary heart disease	Altered Intercellular Communication	Infection with Helicobacter pylori, coronary heart disease, cardiovascular risk factors, and systemic inflammation: the Third National Health and Nutrition Examination Survey.	15586651
Inflammation, Metabolic Syndrome X, Communicable Diseases, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	The null hypothesis was no association of prevalent infection with H. pylori with prevalent coronary heart disease (CHD), systemic inflammation, and variables associated with the metabolic syndrome in American men.	15586651
Pleurisy	Altered Intercellular Communication	Comparatively little has been published on the degree of pleural inflammation and the systemic response and whether this will affect the outcome.	15588036
Pain Distress Question, Fibromyalgia, physiopathological, Chronic pain	Altered Intercellular Communication	The mechanism(s) of nociceptive dysfunction and potential roles of opioid neurotransmitters are unresolved in the chronic pain syndromes of fibromyalgia and chronic low back pain.	15588296
Inflammation, Impaired cognition	Altered Intercellular Communication	Aging may further exacerbate brain metabolites associated with inflammation in HIV patient and thereby increase the risk for cognitive impairment.	15589098
Inflammation, Depression, CTCAE	Altered Intercellular Communication	It was the aim of this study to test the hypothesis that depression in post-MI patients is associated with increased inflammation as compared to non-depressed post-MI patients.	15589561
Inflammation	Altered Intercellular Communication	Several inflammatory markers were however elevated in both cohorts when compared with levels reported in healthy subjects, indicating persistent inflammation several months after MI.	15589561
Inflammation, Depressed mood	Altered Intercellular Communication	There was no indication of increased inflammation in depressed post-MI patients as compared to non-depressed post-MI patients.	15589561
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) involves amyloid beta (Abeta) accumulation, oxidative damage, and inflammation, and risk is reduced with increased antioxidant and anti-inflammatory consumption.	15590663
Inflammation, Cognition Disorders	Altered Intercellular Communication	The phenolic yellow curry pigment curcumin has potent anti-inflammatory and antioxidant activities and can suppress oxidative damage, inflammation, cognitive deficits, and amyloid accumulation.	15590663
Inflammation, Helminths, Colitis	Altered Intercellular Communication	Helminths diminish immune responsiveness in naturally colonised humans and reduce inflammation in experimental colitis.	15591509
Cessation of life, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	The most frequent cause of death in hemodialysis (HD) patients is cardiovascular disease (CVD), and chronic inflammation has been identified as an epidemiologically important risk factor for CVD.	15593040
Inflammation, Atherosclerosis, Autoimmune Diseases, Lupus Erythematosus, Systemic, Antiphospholipid Antibodies	Altered Intercellular Communication	Antiphospholipid antibodies and CRP support the role of inflammation and autoimmunity in the development of accelerated atherosclerosis in SLE.	15593203
Inflammation, Renal Cell Carcinoma Pathway	Altered Intercellular Communication	However, the immunoreactivity of COX-2 in renal cell carcinoma and peritumoral areas with inflammation was greater than in areas without inflammation.	15596182
Renal Cell Carcinoma Pathway	Altered Intercellular Communication	COX-2 expression seems to play a role in the inflammation-carcinoma sequence in renal cell carcinoma.	15596182
Inflammation, Carcinogenesis, Renal Cell Carcinoma Pathway	Altered Intercellular Communication	Additional research is required to determine the link between carcinogenesis and inflammation in renal cell carcinoma.	15596182
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Systemic inflammation has been shown to be associated with an increased risk of acute myocardial infarction (AMI).	15596638
Papilledema, Necrosis	Altered Intercellular Communication	PMMA leakage into the T7-T8 disc was identified without significant disc inflammation or necrosis.	15597484
Inflammation, Squamous cell carcinoma of esophagus, Gastric Cardia Adenocarcinoma	Altered Intercellular Communication	The population of Linxian in north central China is at high risk for gastric cardia adenocarcinoma (GCC) and esophageal squamous cell carcinoma (ESCC), and chronic inflammation may contribute to this risk.	15598788
Inflammation	Altered Intercellular Communication	These variants could confer an altered IL8 expression pattern or interact with environmental factors to increase the risk for inflammation and GCC.	15598788
Inflammation, MVT Regimen, Thrombophilia	Altered Intercellular Communication	Clinical factors, which were thought to contribute to MVT, included underlying hypercoagulability, low-flow state, uncontrolled inflammation, perioperative time period, and prior surgical manipulation of the portal vein following orthotopic liver transplantation.	15599206
Inflammation, Injury of liver, Hepatitis, Chronic, Hepatitis C, Chronic	Altered Intercellular Communication	Liver hepcidin mRNA correlates with iron stores, but not inflammation, in patients with chronic hepatitis C. Liver iron is frequently elevated in chronic hepatitis C and may contribute to liver injury.	15599216
Inflammation, hepcidin	Altered Intercellular Communication	The pathophysiology behind this phenomenon may involve hepcidin, a gene that is up-regulated in the liver by inflammation and iron.	15599216
Hepatic inflammation, Hepatitis C, Hepatitis C, Chronic	Altered Intercellular Communication	To determine whether liver hepcidin mRNA correlates with markers of hepatic inflammation and iron status in patients with hepatitis C, we extracted total RNA from liver biopsy specimens of patients with chronic hepatitis C and quantified hepcidin mRNA.	15599216
Inflammation, Hepatitis, Hepatitis C, Chronic, Hepatitis C, hepcidin	Altered Intercellular Communication	In contrast to other inflammatory states, hepcidin mRNA expression in the liver was independent of markers of inflammation in hepatitis C. Instead, our results suggest that iron stores in patients with hepatitis C regulate hepcidin expression and that iron loading in chronic hepatitis C is not due to inappropriate hepcidin expression.	15599216
Inflammation	Altered Intercellular Communication	DFs with marked inflammatory changes showed slightly higher rates of ssDNA and Ki-67 positivity than did DFs without marked inflammation.	15599344
Communicable Diseases, Inflammation, Hypertrophy	Altered Intercellular Communication	In this case, clinically significant endograft infection was not apparent on the initial computed tomography (CT) scan, however, serial CT scans demonstrated progressive AAA enlargement with increased inflammation.	15599636
vascular inflammations, Atherosclerosis, Chronic inflammatory disorder	Altered Intercellular Communication	Atherosclerosis is a chronic inflammatory disease, however, the mechanisms by which advanced age per se promotes vascular inflammation are not well understood.	15599669
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is typically associated with a low-grade vascular inflammation that can be measured with the highly sensitive C-reactive protein (hs-CRP) assay.	15599677
Tumor necrosis, Inflammation	Altered Intercellular Communication	The tumor necrosis factor (TNF) is one of the most important cytokines of cellular response and inflammation.	15600254
Inflammation, Atherosclerosis	Altered Intercellular Communication	In addition, parameters of oxidative stress, inflammation, and atherosclerosis were evaluated.	15600258
Inflammation, Ulceration, CTCAE, Peptic Ulcer, Perforation (observation)	Altered Intercellular Communication	Peptic ulcer disease (PUD) can present with many complications including inflammation, ulceration and perforation.	15601333
Communicable Diseases, Inflammation	Altered Intercellular Communication	Minor local signs of inflammation and infection are common in pediatric patients during continuous epidural infusion.	15601348
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	There is evidence that chronic inflammation may promote atherosclerotic disease.	15602021
Infertility, Hypogonadism	Altered Intercellular Communication	A 30-year-old man who presented with delayed puberty and infertility was found to have hypogonadism associated with an absence of circulating luteinizing hormone.	15602022
Inflammation, Damage	Altered Intercellular Communication	In addition, the patients in Case bC group showed more severe inflammation of the portal tracts (3.5 +/- 0.8 vs. 3.0 +/- 1.1, P <0.005) and there was a higher prevalence of patients with rhomboid-shaped hepatocytes (26.4% vs. 2.7%, P <0.005), acidophilic bodies (33.8% vs. 1.4%, P <0.0001), sinusoidal inflammation (29.4% vs. 10.3%, P <0.01), lymphoid follicles in the portal tracts (72% vs. 44.1%, P <0.05), Kupffer cell proliferation (29.4% vs. 11.8%, P <0.05), bile duct damage (44.1% vs. 10.3%, P <0.0001), and ductular proliferation (30.9% vs. 2.7%, P <0.001) than in control C group.	15602732
Rheumatoid Arthritis	Altered Intercellular Communication	Among all reasons leading to their inflammation rheumatoid arthritis is mentioned on the first place.	15603400
Fibrinoid necrotizing inflammation	Altered Intercellular Communication	On the basis of clinical view and examinations results, there was considered that fixation in CA joints was due to degenerative changes, which were the result of their rheumatoid inflammation.	15603400
Heart Failure, Diastolic, Inflammation, dihydrofolic acid binding	Altered Intercellular Communication	To evaluate insulin resistance and systemic inflammation in older patients with systolic (SHF) or diastolic heart failure (DHF).	15604330
Inflammation, Congestive heart failure	Altered Intercellular Communication	All markers of systemic inflammation were independently associated with the presence of clinical CHF.	15604330
Refractory anemias, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The chronic inflammation in RA causes fibrosis of the synovial tissue and fibrosis has been associated with terminal differentiation.	15605214
Refractory anemias, Fibrosis Assessment, Chronic inflammation, Disease	Altered Intercellular Communication	Consequently, the fibrosis of synovial tissues in RA patients at later stages of disorder is not associated with proliferation and differentiation of the fibroblasts but rather a consequence of chronic inflammation.	15605214
Inflammation	Altered Intercellular Communication	One can differentiate lidedema in two groups, those that are related to an inflammation and those that are not related to an inflammation.	15605458
Inflammation	Altered Intercellular Communication	We hypothesized that metformin may achieve this by improving endothelial function and chronic, low-grade inflammation.	15606381
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	In patients with type 2 diabetes treated with insulin, metformin treatment was associated with improvement of endothelial function, which was largely unrelated to changes in glycaemic control, but not with improvement of chronic, low-grade inflammation.	15606381
Inflammation, Unspecified visual loss	Altered Intercellular Communication	Visual loss can occur from complications following the inflammation itself and/or iatrogenic induced by the chronic use of corticosteroids.	15606476
Inflammation, Crohn Disease-like Reaction	Altered Intercellular Communication	Furthermore, 19/24 of MMF-patients showed characteristic histological alterations of the mucosa that were Crohn's disease-like: discontinuous crypt architectural distortion, increased epithelial mucin secretion, mildly active inflammation and focal presence of dilated and inflamed crypts.	15606581
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Oxidative stress caused by airway inflammation is increased in chronic obstructive pulmonary disease (COPD) and may account for the progressive deterioration of structure and function of the respiratory tract observed in this disease.	15607126
Sample Size Calculation, Inflammation, Vascular System Injuries	Altered Intercellular Communication	Up regulated expression of fractalkine and CX(3)CR1 cooperatively augments the recruitment of mononuclear cells expressing CX(3)CR1 into the affected tissue of SSc, leading to inflammation and vascular injury.	15608300
Refractory anemias, Rheumatoid Arthritis, Inflammation, Inflamed joint	Altered Intercellular Communication	To determine if the local application of x rays to inflamed joints in rheumatoid arthritis (RA) affects the signs and symptoms of inflammation.	15608312
Inflammation, Hypoproteinemia	Altered Intercellular Communication	Laboratory data showed hypoproteinemia in all cases; markers of inflammation such as C-reactive protein were negative.	15610079
Inflammation, Liver carcinoma, Communicable Diseases, Hepatitis C, FAM126A gene	Altered Intercellular Communication	Hepatitis C virus (HCV) infection causes chronic inflammation and increases the risk of hepatocellular carcinoma (HCC).	15610307
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	We have shown previously that concentrations of stool decay-accelerating factor (DAF; CD55), a complement regulatory protein, in patients with ulcerative colitis (UC) are increased in relation to the severity of the colonic mucosal inflammation.	15610450
Hormone abnormality, ARCN1 gene, Edema, Hyponatremia	Altered Intercellular Communication	Renal and hormonal abnormalities, manifesting as oedema or hyponatraemia, are often seen in patients with COPD.	15612959
Headache	Altered Intercellular Communication	Our experience suggests that headache syndromes may arise due to disturbance of serotonergic neurotransmission within deep brain structures.	15613166
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Markers of low-grade inflammation and soluble cell adhesion molecules in Chinese patients with coronary artery disease.	15614337
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Markers of low-grade chronic inflammation, such as C-reactive protein (CRP) and soluble cell adhesion molecules (sCAMs), have been associated with coronary artery disease (CAD).	15614337
Inflammation, Vasculitis of the skin, Fever, CTCAE	Altered Intercellular Communication	Mycoplasma pneumoniae is a bacterial agent that must be evoked when confronted with cutaneous vasculitis, notably within a context of fever and inflammation, and despite the absence of respiratory symptoms.	15615246
Inflammation, Ischemic, Arteriopathic disease	Altered Intercellular Communication	When ischaemic symptoms manifest themselves in young individuals (<40 years), rare causes of obliterative arterial disease, such as inflammation or post-traumatic vascular injury, must be excluded.	15615277
Inflammation, Corneal Stroma, Corneal Ulcer	Altered Intercellular Communication	In a study of corneal buttons obtained from patients of corneal ulcer undergoing therapeutic keratoplasty, we observed loss of keratocytes in the normal appearing corneal stroma, surrounding the zone of inflammation.	15617577
Inflammation	Altered Intercellular Communication	The inflammatory cells in the zone of inflammation also show evidence of apoptotic cell death.	15617577
Inflammation	Altered Intercellular Communication	Our results imply that chronic inflammation caused by excess nitric oxide generated by iNOS contributes to Helicobacter pylori-induced gastric cancer.	15617837
Intraocular inflammation	Altered Intercellular Communication	Postoperatively, the patient developed a chronic, low-grade intraocular inflammation.	15617941
Intraocular inflammation	Altered Intercellular Communication	The low-grade intraocular inflammation persisted with intensive topical steroid-antibiotic medication and systemic antibiotics.	15617941
Pneumonitis, Pulmonary Fibrosis	Altered Intercellular Communication	In addition, there were no significant differences between transgenic mice and nontransgenic littermate controls in the development of pulmonary inflammation or pulmonary fibrosis in response to intratracheal bleomycin instillation.	15618451
Traumatic injury, Pneumonia	Altered Intercellular Communication	Suppression of high-affinity PMN receptors, like CXCR2, may predispose to pneumonia after trauma or other inflammatory conditions that lead to systemic inflammatory response syndrome.	15618463
Inflammation	Altered Intercellular Communication	The operative findings regarding gallbladder wall thickness and inflammation were compared to ultrasound results and histology.	15619487
ACSM3 gene, Inflammation, Cerebral Vasospasm	Altered Intercellular Communication	Considering these data and the biological activities of 8-iso-PGF2alpha, such as development of inflammation, membrane perturbation and vasoconstriction, we conclude that 8-iso-PGF2alpha may play a role in delayed cerebral vasospasm after SAH.	15619547
ARCN1 gene	Altered Intercellular Communication	The combination of multiple modalities was chosen because the patient was in a pre-existing inflammatory condition and had severe COPD.	15619971
Inflammation, Sore to touch	Altered Intercellular Communication	A prospective randomized trial was undertaken to compare the influence of absorbable and non-absorbable sutures on pillar pain, scar tenderness, extent of wound inflammation and overall outcome of the surgery following open carpal tunnel release.	15620502
Autoimmune Diseases, MYELODYSPLASTIC SYNDROME, Miller Dieker syndrome	Altered Intercellular Communication	Several paraneoplastic inflammatory conditions, particularly autoimmune diseases, have been described in association with myelodysplastic syndromes (MDS).	15621795
Inflammation	Altered Intercellular Communication	Bronchoscopy showed chronic inflammation and post-tuberculosis (TB) scars in bronchi without acid-fast bacilli in bronchoalveolar lavage (BAL) in culture and polymerase chain reaction (PCR) tests.	15621842
Optic Neuritis	Altered Intercellular Communication	Her final acuity of 20/50 was thought to be due to presumed previous attacks of optic neuritis and anterior segment inflammation.	15621873
Ischemia, Thrombosis, Inflammation, Vasculitis, CTCAE, Behcet Syndrome	Altered Intercellular Communication	Ischemia and inflammation are common in Behcet's disease and sometimes thrombosis and vasculitic changes may cause a decrease in vision.	15621873
Inflammation	Altered Intercellular Communication	Neovascularization and inflammation are potential consequences that lead to the appearance of small vessels.	15622371
Inflammation, Fatty degeneration, Balloon Dilatation	Altered Intercellular Communication	Liver biopsy showed moderate steatosis, moderate inflammation, ballooning degeneration, and Mallory bodies.	15622489
Inflammation	Altered Intercellular Communication	An acute nonspecific inflammation with no lymphomononuclear-plasmacytic component was observed on Day 0.	15622578
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Inflammation can predispose to myocardial infarction (MI), and mannan binding lectin (MBL) promotes phagocytic clearance of inflammatory agents, but the predictive value of MBL levels for MI is not known.	15623574
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Microscopic examinations of both the liver and spleen showed mycobacteria-related granulomatous inflammation and caseating necrosis.	15624045
Inflammation	Altered Intercellular Communication	If the production of ROS was persistent, it would result in chronic inflammation and the imbalance of oxidative-reductive status in those patients.	15624367
Hemorrhagic, Inflammation, Choroidal Neovascularization	Altered Intercellular Communication	In patients who manifest exudative, hemorrhagic retinopathy, with no signs of active inflammation or an anatomic predisposition to choroidal neovascularization, PCV should be considered.	15624672
Narcolepsy, Sleep Disorders	Altered Intercellular Communication	Narcolepsy is a sleep disorder caused by disruption of hypocretin (orexin) neurotransmission.	15625087
Inflammation, Traumatic injury	Altered Intercellular Communication	The etiology of sinus mucoceles remains somewhat obscure, but favorizing factors can be broadly divided in two: inflammation and trauma.	15626255
Multiple polyps, Inflammation, Nasal Polyps, Traumatic injury	Altered Intercellular Communication	Patients suffering from nasal polyposis offer a unique group for the study of mucoceles as they present the factor of inflammation related to their polyposis, and the factor of trauma when being treated surgically.	15626255
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The local inflammation associated with H. pylori infection is characterized by an increased production of the proinflammatory cytokines IL-1-B, IL-6, IL-8 and TNF-alpha.	15627645
Orchitis	Altered Intercellular Communication	The presence of the needle in the right iliac fossa on plain roentgenogram along with signs of appendicular inflammation on clinical and laboratory evaluation provided a clue to the diagnosis.	15627662
Inflammation, Affection	Altered Intercellular Communication	Peculiarities of histological assessment of pleural biopsies were noted, characteristic morphological signs, observed in the main pleural pathological processes: nonspeciphic inflammation, tuberculous inflammation, tumoral and metastatic affection.	15628238
Inflammation, Ischemic stroke	Altered Intercellular Communication	[Markers of inflammation, autoantibodies to neurospecific antigens and outcome in patients with acute ischemic stroke].	15628589
Inflammation, Bradycardia, Cardiac Arrhythmia	Altered Intercellular Communication	No proarrhythmia or clinical relevant bradycardia was observed, and no inflammation detected at the site of venous access.	15628645
Inflammation	Altered Intercellular Communication	Histological data showed a normal gallbladder wall in only 4 cases; 101 examinations revealed some kind of (chronic) inflammation, which was not different from histological gallbladder results in patients without prior lithotripsy.	15628729
Microalbuminuria, Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	No additional association between trace- and/or any microalbuminuria and general characteristics of patients, specific factors related to general disease as a cause of ocular inflammation, location of uveitis, duration of uveitis, and medication was found.	15629293
Inflammation	Altered Intercellular Communication	The goal of this study was to determine whether chronic inflammation of the vascular wall may be associated with an impaired activation of the fibrinolytic system.	15629369
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays an important role in the initiation and progression of atherosclerosis, and the fibrinolytic system may prevent local thrombus formation.	15629369
Inflammation	Altered Intercellular Communication	Chronic low-grade inflammation is associated with enhanced activation of endogenous fibrinolysis at baseline but a reduced fibrinolytic response to VO.	15629369
Inflammation, Fatty degeneration	Altered Intercellular Communication	Severity of steatosis, inflammation, hepatocyte ballooning and Mallory's hyaline improved significantly.	15629518
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Increased levels of gelatinase B/matrix metalloproteinase-9 have been reported for cataract-associated disorders such as eye inflammation and diabetes.	15629892
Inflammatory abnormality of the eye	Altered Intercellular Communication	The ocular inflammation, by unknown chemical mediators, was likely responsible for the excessive eyelash growth.	15629970
Inflammation, Hemorrhage, Meckel Diverticulum, Obstruction	Altered Intercellular Communication	The most common complications associated with a Meckel's diverticulum include obstruction, bleeding, and inflammation (7, 9, 11, 18-20).	15630649
Inflammation, Fever, CTCAE, Peritonitis, Serositis, Conjunctivitis, Arthralgia/arthritis, Myalgia, CTCAE 5	Altered Intercellular Communication	Clinically, episodes of severe myalgia, arthralgia/arthritis, sterile peritonitis, scrotal inflammation, serositis, migratory rash, conjunctivitis, and recurrent fever are characteristic.	15630744
Bile Reflux, Inflammation, Atrophic	Altered Intercellular Communication	A bile reflux co-exists with diminished acute and chronic inflammation activity and atrophy level.	15631317
Communicable Diseases, Stomach Carcinoma	Altered Intercellular Communication	infection may cause progression to gastric cancer not by traditional stepwise: inflammation-atrophy-metaplasia.	15631317
Vasculitis, Coronary angiography, Diabetes Mellitus	Altered Intercellular Communication	Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes.	15632890
vascular inflammations, Diabetes Mellitus	Altered Intercellular Communication	We evaluated whether the Asp299Gly polymorphism in the TLR4 gene, which impairs inflammatory responses, is associated with reduced vascular inflammation (assessed by C-reactive protein [CRP]) and a decreased risk for CAD and diabetes.	15632890
Inflammation, Overweight	Altered Intercellular Communication	Low-grade systemic inflammation in overweight children: impact of physical fitness.	15633587
Inflammation, Tumor necrosis, Obesity	Altered Intercellular Communication	Increased inflammation has recently been addressed to play an important role for the relationship between obesity and CAD, as adipose tissue expresses and releases pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha).	15633587
methionine, Inflammation, Obesity	Altered Intercellular Communication	When dividing the children into groups regarding obesity (BMI < 22.5 kg/mz, BMI > or = 22.5 kglm2) and fitness (< 5 MET, > or = 5 MET), we found that obese, unfit children showed the highest systemic inflammation, whereas fit but obese individuals had as low levels as lean and fit children.	15633587
Idiopathic Inflammatory Myopathies, Inflammation	Altered Intercellular Communication	In conclusion, the upregulation of beta chemokines and receptors in IIM and their differential expression by various cells may contribute to chronic inflammation and to the peculiar distribution of inflammatory exudates in these diseases.	15634233
Inflammation	Altered Intercellular Communication	In contrast, PMN persistence characterizes the early stages of chronic inflammation.	15635048
Inflammation, Craniosynostosis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Intranasal amphotericin B reduced inflammatory mucosal thickening on both CT scan and nasal endoscopy and decreased the levels of intranasal markers for eosinophilic inflammation in patients with CRS.	15637558
Nonalcoholic Steatohepatitis, Fibrosis Assessment, Hepatitis, Fatty Liver Disease	Altered Intercellular Communication	The pathogenesis of occurrence of liver inflammation and fibrosis in patients with nonalcoholic steatohepatitis (NASH) is not completely understood.	15637751
Inflammation, Elastosis perforans serpiginosa	Altered Intercellular Communication	Thirty healthy males without inflammation in EPS were selected as controls.	15638019
Inflammation, prostatitis, Elastosis perforans serpiginosa	Altered Intercellular Communication	In III A prostatitis, the PSA level was elevated with the increase of inflammation in EPS, but with no significant difference.	15638019
Inflammation	Altered Intercellular Communication	[Leukocyte-adhesion deficiency: a rare disorder of inflammation].	15638198
Inflammation, Helicobacter pylori	Altered Intercellular Communication	Histopathological changes in the antral mucosa of children with Helicobacter pylori are characterized by an increased infiltrate of macrophages, dependent on the severity grade of inflammation.	15638432
vascular inflammations	Altered Intercellular Communication	Patient analyses before and after the intervention period included serum fatty acid profile, serum lipoproteins, and markers of vascular inflammation.	15638820
Schizophrenia	Altered Intercellular Communication	The gene coding for the 5-HT transporter (5-HTT) is considered as a candidate gene for schizophrenia, because this transporter plays a key role in serotonin neurotransmission.	15638952
Polymyositis, Dermatomyositis, Myositis, CTCAE 5.0, Inflammation	Altered Intercellular Communication	Polymyositis, dermatopolymyositis, and inclusion body myositis imply chronic inflammation of skeletal muscles.	15639118
Coughing, Inflammation, Bronchial Hyperreactivity	Altered Intercellular Communication	Cough may be the consequence of bronchial hyperresponsiveness (BHR) and inflammation.	15640336
Inflammation	Altered Intercellular Communication	Regression of inflammation in the scar provides a simple way to monitor response to treatment in this multisystem disease.	15640432
Inflammation	Altered Intercellular Communication	Such an increase has been considered as a sign of chronic inflammation.	15640602
Communicable Diseases, Inflammation, Hepatitis C	Altered Intercellular Communication	Chronic viral hepatitis C (HCV) infection, highly prevalent in hemodialysis patients, is also a disease that can induce chronic inflammation.	15640602
Inflammation	Altered Intercellular Communication	This suggests a potential pathway that would account for the diminished synovial inflammation and the decreased numbers of synovial macrophages evident after TNF blockade.	15641091
Inflammation	Altered Intercellular Communication	Laparotomy was performed and a severe local inflammation was noted in the pelvic cavity.	15641223
Inflammation, Infection caused by Helicobacter pylori, Cardia of stomach, Affection	Altered Intercellular Communication	Little is known about the affection of the gastric cardia by inflammation associated with H. pylori infection.	15641226
Inflammation	Altered Intercellular Communication	Chronic inflammation and its activity reached similar values in the antrum and cardia, the difference was not statistically significant (p>0.05).	15641226
Inflammation	Altered Intercellular Communication	Significantly higher values were recorded in chronic inflammation, its activity and number of HP in the antrum (p<0.001).	15641226
Inflammation, Dysplasia, Atrophic	Altered Intercellular Communication	Conversely chronic inflammation, activity and HP in the cardia were significantly higher than in the corpus (p<0.001), similarly IM and lymphoid follicles (p<0.01), atrophy and dysplasia (p<0.05).	15641226
Inflammation	Altered Intercellular Communication	The inflammation, activity and other mucosal changess were examined semiquantitatively and evaluated according to the Sydney System.	15641227
Inflammation	Altered Intercellular Communication	In the cardia, corpus and antrum a significant decline of chronic inflammation was recorded as well as of the activity and H.pylori (p<0.001).	15641227
Stomach Diseases, Inflammation, Hemorrhage, Intestinal metaplasia, Atrophic	Altered Intercellular Communication	Chronic inflammation, atrophy and intestinal metaplasia persisted, although with a lower intensity, and signs of chemical gastropathy with haemorrhage in the oesophageal papillae developed.	15641227
Chlamydia, Healthcare associated pneumonia	Altered Intercellular Communication	Chlamydia pneumoniae (CP) causes frequently nosocomial pneumonia and other inflammations of the upper and lower airways.	15641238
Inflammation, Stenosis, Traumatic injury	Altered Intercellular Communication	The causes of the strictures in 3 (60%) cases were due to medical treatment, in 1 (20%) case due to trauma and in 1 (20%) case due to inflammation.	15641557
Inflammation, Asthma, physiopathological	Altered Intercellular Communication	Initial maintenance treatment of the two main components of asthma, inflammation, and smooth muscle dysfunction (e.g., bronchoconstriction), with FSC results in greater overall improvements in asthma control compared with treatment of either individual component alone.	15641629
Inflammation, Malignant Neoplasms, Thrombophilia	Altered Intercellular Communication	The trend toward a higher prevalence of malignancy in this unique patient group raises the possibility of malignancy-induced hypercoagulability or inflammation as an underlying etiologic factor.	15642564
Leydig Cell Tumor, LCT gene	Altered Intercellular Communication	Both clinical and hormonal findings normalized following surgical exeresis of a left testicular mass, which proved to be a Leydig cell tumour (LCT) at histology.	15644061
Acute Lung Injury, Inflammation	Altered Intercellular Communication	Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury.	15644641
Inflammation	Altered Intercellular Communication	The severity of inflammation varies with clinical risk factor, suggesting that clinical risk factor should be considered when both developing and testing therapeutic interventions.	15644641
Inflammation	Altered Intercellular Communication	Although, the causal pathway is not entirely clear, it seems that both insulin resistance and chronic low-grade systemic inflammation may be involved.	15645205
pancolitis, Inflammation	Altered Intercellular Communication	Two patients showed diffuse pancolitis without caecal involvement, in 5 cases there was inactive inflammation in the rectum or in the sigmoid colon.	15645850
Gingivitis, Tooth Loss, Inflammatory disorder	Altered Intercellular Communication	Periodontal diseases are polymicrobial-induced inflammatory diseases, and they vary from mild gingival inflammation to severe deterioration of the periodontium, ie, loss of periodontal supportive tissues and, ultimately, tooth loss.	15645886
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Comparison of magnetic resonance imaging colonography with conventional colonoscopy for the assessment of intestinal inflammation in patients with inflammatory bowel disease: a feasibility study.	15647190
Inflammatory Bowel Diseases, Colitis	Altered Intercellular Communication	To evaluate this approach for patients with inflammatory bowel disease (IBD), we compared MRI based colonography with conventional colonoscopy for assessing the presence and extent of colonic inflammation.	15647190
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	With colonoscopy serving as the gold standard, the sensitivity for correctly identifying inflammation on a per segment analysis of the colon was 31.6% for Crohn's disease (CD) and 58.8% for ulcerative colitis (UC).	15647190
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In CD, in most cases mild inflammation was not diagnosed by MRI while in UC even severe inflammation was not always depicted by MRI.	15647190
Inflammatory Bowel Diseases, Colitis	Altered Intercellular Communication	MRI based colonography is not suitable for adequately assessing the extent of colonic inflammation in patients with IBD.	15647190
Colitis	Altered Intercellular Communication	Only severe colonic inflammation in patients with CD can be sufficiently visualised.	15647190
Inflammation, Blood Clot	Altered Intercellular Communication	A particular feature of this case was the radiological demonstration of complete regression of the thrombus and the hepatic parenchymal changes, upon resolution of the inflammation and normalization of the platelet count.	15647643
Acute inflammation	Altered Intercellular Communication	Subanalysis of these 12 patients revealed a success rate of 92%, as opposed to 24% in cases without acute inflammation.	15647649
Uremia, Inflammation	Altered Intercellular Communication	The goals of the study are (1) to validate bioimpedance technology against gold-standard methods for assessment of the various body compartments, (2) to directly quantify visceral adipose tissue mass, a potential source of cytokine production (adipokines) promoting chronic inflammation, and to study its relation to inflammatory markers, and (3) to directly quantify visceral organ mass and to study its relation to uremia toxin generation as assessed by protein catabolic rate and resting energy expenditure.	15648026
Inflammation, Inflammatory Myofibroblastic Tumor	Altered Intercellular Communication	Mass-like lesions with histologic features of nonspecific inflammation and mesenchymal repair have been designated as inflammatory pseudotumors.	15648289
Inflammation, Data types - Address	Altered Intercellular Communication	Local inflammation caused by intrahippocampal lipopolysaccharide injection significantly increased the engraftment of BM-derived cells in old AD mice and decreased the hippocampal Abeta burden.	15649704
Cessation of life, Rupture, Inflammation, Aneurysm	Altered Intercellular Communication	There was one early death from rupture of a second undiagnosed aneurysm and two late deaths from rupture due to persistent inflammation.	15649719
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	Markers of coagulation activation, endothelial stimulation and inflammation in patients with peripheral arterial disease.	15649725
Inflammation, Pulmonary Hypertension, Meconium Aspiration Syndrome	Altered Intercellular Communication	Pulmonary hypertension and inflammation are well-identified pathogenetic features in meconium aspiration syndrome of newborns, but current approaches to their treatment or prevention are still often unsatisfactory.	15650305
Inflammation	Altered Intercellular Communication	An extensive work-up revealed laboratory signs of inflammation and a mild thickening of the aortic wall on computed tomographic scan of the thorax.	15650810
Inflammation, Neoplasms	Altered Intercellular Communication	The precise role of chemokines in neovascularization during inflammation or tumor growth is not yet fully understood.	15652347
Inflammation	Altered Intercellular Communication	Antral inflammation was associated with TNF-A -1031 TT, while corpus activity with IL-10 -819 CC.	15652446
Pituitary Adenoma, Ovarian hyperstimulation	Altered Intercellular Communication	Follicle-stimulating hormone-secreting pituitary adenoma may present as acute spontaneous ovarian hyperstimulation.	15652911
Acute Coronary Syndrome, Inflammation, Myocardial Infarction	Altered Intercellular Communication	Pregnancy-associated plasma protein-A levels in patients with acute coronary syndromes: comparison with markers of systemic inflammation, platelet activation, and myocardial necrosis.	15653020
Ischemia, Inflammation, Myocardial Infarction, GDC AJCC Clinical Stage Terminology, Acute chest pain	Altered Intercellular Communication	In 547 patients with angiographically validated ACS and in a heterogeneous emergency room population of 644 patients with acute chest pain, respectively, PAPP-A as well as markers of myocardial necrosis (troponin T [TnT]), ischemia (vascular endothelial growth factor [VEGF]), inflammation (high-sensitivity C-reactive protein [hsCRP]), anti-inflammatory activity (interleukin [IL]-10), and platelet activation (soluble CD40 ligand [sCD40L]) were determined.	15653020
Inflammation, Angina, Unstable	Altered Intercellular Communication	Persistent systemic inflammation in unstable angina is largely unrelated to the atherothrombotic burden.	15653021
Inflammation, Thrombosis, Atherosclerosis	Altered Intercellular Communication	The aim of this study was to assess the relationship between systemic inflammation, atherosclerosis, and thrombosis in two distinct clinical models of atherothrombosis.	15653021
Inflammation, Coronary Thrombosis	Altered Intercellular Communication	Persistent unstable angina (UA) is commonly associated with coronary thrombosis and persistent systemic inflammation.	15653021
Inflammation, Thrombosis	Altered Intercellular Communication	Such a large, consistent discrepancy between atherothrombotic burden and systemic inflammation suggests that atherothrombosis, by itself, is an unlikely cause of persisting, recurring UA.	15653021
Inflammation	Altered Intercellular Communication	However, decreased myocardial TNF-alpha may be a marker of a general statin-mediated decrease in inflammation in the transplanted heart that leads to improved graft and patient survival.	15653378
Inflammation, Atherosclerosis	Altered Intercellular Communication	Autopsy confirmed severe narrowing of proximal cerebral vasculature with absence of inflammation or atherosclerosis.	15654044
Inflammation, Moyamoya Disease, Vascular Diseases, Meningitis	Altered Intercellular Communication	The inflammation and subsequent postinfectious autoimmune response associated with meningitis can lead to a progressive vasculopathy and may represent a pathophysiologic mechanism for the arterial occlusions seen in moyamoya syndrome.	15654044
Oro-facial gangrene, Inflammation	Altered Intercellular Communication	Evolution from an intraoral inflammation to a grotesque oro-facial gangrene is very rapid.	15655015
Inflammation, Acanthosis, Papillomatosis, Necrosis	Altered Intercellular Communication	Histologic examination revealed confluent upper epidermal necrosis, acanthosis, papillomatosis, and superficial and deep perivascular inflammation.	15655150
Inflammation	Altered Intercellular Communication	Chronic inflammation contributes to the pathogenesis of several complications of hemodialysis therapy.	15655319
Inflammation, Milligram per liter fibrinogen equivalent unit	Altered Intercellular Communication	We examined the effect of ultrapure dialysate which contributes to chronic inflammation with hs-CRP and tried to reduce endotoxin (ET) levels at the end of the dialysate from 70 EU/l to <1.0 EU/l (ultrapure dialysate).	15655319
Gastritis	Altered Intercellular Communication	Furthermore, expression of TRAIL and TRAIL-R1 and -R2 correlated inversely with the severity of gastric inflammation.	15655781
Inflammation	Altered Intercellular Communication	Airway remodeling and inflammation in symptomatic infants with reversible airflow obstruction.	15657459
Inflammation, Asthma, Thickened	Altered Intercellular Communication	We hypothesized that the epithelial reticular basement membrane (RBM) thickening and eosinophilic inflammation characteristic of asthma would be present in symptomatic infants with reversible airflow obstruction.	15657459
Inflammation, Asthma, MS4A2 wt Allele, Thickened	Altered Intercellular Communication	RBM thickening and the eosinophilic inflammation characteristic of asthma in older children and adults are not present in symptomatic infants with reversible airflow obstruction, even in the presence of atopy.	15657459
Specimen Type - Fistula, Aortic Aneurysm, Spondylitis	Altered Intercellular Communication	On pathologic examination a fistula between the small aortic aneurysm and duodenum and periaortic inflammation in contact with a spondylitis were found.	15657719
Traumatic injury	Altered Intercellular Communication	Ultrasound is useful in detecting acromioclavicular pathologies in cases of trauma, inflammations and degenerative changes.	15658142
Inflammation, Granulomatous, Lymphocyte count increased	Altered Intercellular Communication	Neuropathology reveals angiodestructive inflammation, often granulomatous, and meningeal lymphocytosis.	15659428
Inflammation, "Alzheimers Disease", Encephalitis	Altered Intercellular Communication	Our findings (i) help to dissect one separate clinicopathological entity from what is likely to be a spectrum of primary angiitides of the CNS; (ii) have important therapeutic implications for one category of patients with amyloid-related vasculopathy; and (iii) may provide valuable insights into the development of amyloid-associated inflammation, of relevance not only to ABRA but also to Abeta-immunization-related encephalitis and to Alzheimer's disease.	15659428
Inflammation	Altered Intercellular Communication	Low-grade inflammation with aging has consequences for T-lymphocyte signaling.	15659789
Inflammation	Altered Intercellular Communication	However, there are no clear data concerning the basal state of activation of T lymphocytes and its putative link with the low-grade inflammation observed with aging.	15659789
Inflammation	Altered Intercellular Communication	In conclusion, we show a link between aging, T-lymphocyte lipid rafts, immune senescence, and low-grade inflammation.	15659789
Lesion, Inflammation	Altered Intercellular Communication	Laparoscopic surgery for large renal lesion or kidneys with chronic inflammation has proved to be technically challenging.	15659900
Pyelonephritis, Xanthogranulomatous, Inflammation	Altered Intercellular Communication	The main indications for surgery were chronic inflammation and xanthogranulomatous pyelonephritis.	15659900
Inflammation, Carcinogenesis	Altered Intercellular Communication	Cyclooxygenase-2 (Cox-2) is undetectable in most normal tissues, but it is induced in various cell types by inflammation and carcinogenesis.	15660656
Inflammation	Altered Intercellular Communication	Eotaxin1 plays a pivotal role in eosinophil-associated inflammation.	15661912
vascular inflammations, Myocardial Infarction	Altered Intercellular Communication	Myocardial connective tissue growth factor (CTGF) mRNA and protein expressions were increased by 300% in dTGR (P < 0.05), especially in areas with myocardial infarctions and vascular inflammation.	15662226
Uveomeningoencephalitic Syndrome, Choroiditis	Altered Intercellular Communication	Magnetic resonance imaging of choroidal inflammation in Vogt-Koyanagi-Harada disease.	15662244
Uveomeningoencephalitic Syndrome, Choroiditis	Altered Intercellular Communication	This is the third report of the magnetic resonance imaging visualization of choroidal inflammation in Vogt-Koyanagi-Harada disease and shows the imaging abnormalities in finer detail than earlier reports.	15662244
Inflammation	Altered Intercellular Communication	Most importantly, the omentum readily adheres to areas of inflammation and peritoneal damage, often leading to adhesion formation.	15662530
Eosinophilic inflammation	Altered Intercellular Communication	Eosinophil inflammation is present in nasal and bronchial mucosa and a clear link between upper and lower airways exists.	15662963
Asthma, Nasal inflammation, Rhinitis, Allergic, Perennial	Altered Intercellular Communication	Our aim was to evaluate whether nasal inflammation correlates with lung function in patients with perennial allergic rhinitis associated with asthma.	15662963
Airway structure, IL13 gene	Altered Intercellular Communication	CONCLUSIONS Nasal cytology may be considered a non-invasive tool to assess airway inflammation in mild asthmatics with associated allergic rhinitis.	15662963
Inflammation, Damage, Lung Injury, Traumatic injury	Altered Intercellular Communication	Although trauma patients often suffer direct lung damage, an equally destructive mechanism of lung injury involves postinjury systemic inflammation.	15664090
Inflammation, Traumatic injury	Altered Intercellular Communication	We postulate that secretory phospholipase A(2) (sPLA(2)) release induced by trauma relates to systemic inflammation that compromises both lung function and clinical status after injury.	15664090
Presenile dementia, Inflammation, Cerebral atrophy	Altered Intercellular Communication	It has long been known that the spirochete Treponema pallidum, which is the infective agent for syphilis, can in its late stages cause dementia, chronic inflammation, cortical atrophy and amyloid deposition.	15665404
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	These then cause a cytokine cascade and microlocalized inflammation in the CNS, that in time results in clinical Alzheimer's disease.	15665405
Inflammation, Cytomegalovirus Infections, Tuberculosis, Colitis, Ischemic, Colitis, Ulcerative Colitis, pseudomembranous colitis, Crohn Disease, Behcet Syndrome	Altered Intercellular Communication	Histopathologic findings of these lesions included acute nonspecific inflammation, chronic nonspecific inflammation, Crohn's disease, tuberculous colitis, ischemic colitis, Behcet's disease, cytomegalovirus infection, eosinophilic colitis, ulcerative colitis or pseudomembranous colitis, but most of them were nonspecific (84%).	15665576
Crohn Disease, Acute inflammation	Altered Intercellular Communication	Two patients with acute inflammation, who showed no improvement in symptoms and lesions, were later diagnosed as Crohn's disease.	15665576
Chronic suppurative inflammation	Altered Intercellular Communication	Microscopic examination of a transbronchial biopsy specimen revealed chronic suppurative inflammation, which did not regress despite intensive antibiotic therapy for a period of two months.	15666630
Inflammation, Dermatitis, Atopic, Data types - Address, Erythema, Dry skin, Pruritus, Eczema	Altered Intercellular Communication	Atopic dermatitis (AD), often called eczema, is characterized by intense pruritus, erythema, dry skin, and inflammation.	15667233
Abdominal Pain	Altered Intercellular Communication	A repeat biopsy after reduction of sirolimus dose by 50% over 6 months showed mild chronic inflammation of stomach and duodenum with some improvement in abdominal pain.	15667620
Inflammation, Swelling	Altered Intercellular Communication	Because of persistent inflammation and painful swelling of the epididymides and testes, the patient underwent bilateral orchiectomy.	15667898
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	C-reactive protein (CRP), a marker of inflammation, is increasingly measured to stratify coronary artery disease risk and guide clinical management.	15668370
Ischemia, Inflammation, Necrosis	Altered Intercellular Communication	Critical ischemia leads to the production of reactive oxygen species (ROS) at concentrations exceeding the body's antioxidant capacity, causing inflammation and necrosis in ischemic tissues.	15668637
Inflammation, Myocardial Infarction	Altered Intercellular Communication	Case 2 showed acute inflammation and severe myocardial necrosis with neutrophilic abscess, lymphocyte and macrophage infiltration, cell debris and purulent exudate.	15668804
Granulomatous inflammation	Altered Intercellular Communication	Histopathology showed foreign material associated with granulomatous inflammation.	15670177
Inflammation, Electrocardiogram: myocardial infarction (finding), Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Cox regression analyses demonstrated a hazard ratio of 3.8 for incident first myocardial infarction or fatal CHD after adjusted for multiple risk factors, including markers of inflammation.	15670554
Conjunctivitis	Altered Intercellular Communication	Recurrence was associated with tarsal conjunctival inflammation (OR: 2.4; 95% confidence interval [CI]: 1.6-3.8) and residence in the Kongwa district (OR: 2.3; 95% CI: 1.2-4.6).	15671268
Inflammation	Altered Intercellular Communication	Recurrence is associated with evidence of inflammation in the tarsal conjunctiva, although it is not clear whether the inflammation contributes to recurrence, or is a result of the recurrence.	15671268
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic inflammation of the lung is a characteristic finding in chronic obstructive pulmonary disease (COPD).	15672852
Inflammation	Altered Intercellular Communication	Leptin is a pleiotropic cytokine thought to play a role in host response to inflammation.	15672852
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Markers of inflammation and oxidative stress in exacerbated chronic obstructive pulmonary disease patients.	15672854
ARCN1 gene, Inflammation	Altered Intercellular Communication	Several cytokines and cell adhesion molecules enhancing a mainly neutrophilic inflammation have been associated with COPD.	15672854
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The metabolic syndrome and inflammation: association or causation?	15673055
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The aim of this editorial was to discuss evidence indicating a role for low-grade inflammation as a pathogenetic event of the metabolic syndrome.	15673055
Inflammation, Sialorrhea, Metabolic Syndrome X, Diabetes Mellitus	Altered Intercellular Communication	Chronic inflammation may represent a triggering factor in the origin of the metabolic syndrome: stimuli such as overnutrition, physical inactivity, and ageing would result in cytokine hypersecretion and eventually lead to insulin resistance and diabetes in genetically or metabolically predisposed individuals.	15673055
Inflammation, Endothelial dysfunction, Metabolic Syndrome X	Altered Intercellular Communication	The proinflammatory state that accompanies the metabolic syndrome associates with both insulin resistance and endothelial dysfunction, providing a connection between inflammation and metabolic processes which is highly deleterious for vascular functions.	15673055
Inflammation, Acute renal failure due to ischemia	Altered Intercellular Communication	Because of this, an inhibitor of the alternative pathway might limit complement activation and inflammation after ischemia/reperfusion, thereby protecting the kidney from ischemic acute renal failure.	15673300
HD Term Type, Inflammation	Altered Intercellular Communication	The results in this pilot study show that the removal of large solutes by PLD can improve some indices of chronic inflammation in HD patients.	15673326
Inflammation	Altered Intercellular Communication	Inflammation contributes to morbidity following on-pump cardiac surgery.	15673408
Inflammation	Altered Intercellular Communication	Relation of markers of inflammation (C-reactive protein, white blood cell count, and lipoprotein-associated phospholipase A2) to the ankle-brachial index.	15675180
Inflammation, atherosclerotic	Altered Intercellular Communication	Markers of inflammation are predictive of cardiovascular events but their association with atherosclerotic burden remains poorly defined.	15675180
Inflammation, atherosclerotic	Altered Intercellular Communication	We hypothesized that markers of inflammation, including C-reactive protein (CRP), white blood cell (WBC) count, and lipoprotein-associated phospholipase A2 (Lp-PLA2), would be associated with the ankle-brachial index (ABI), a marker of atherosclerotic burden.	15675180
Pain Distress Question, Basal, Hyperalgesia	Altered Intercellular Communication	This latter finding may account for the decreased pain observed in this group; this cytokine is known to mediate basal pain sensitivity and induce hyperalgesia in inflammatory conditions.	15675987
Microalbuminuria, Inflammation, Blood Vessel	Altered Intercellular Communication	We hypothesized that microalbuminuria and C-reactive protein (CRP), a marker of generalized vascular damage and inflammation, respectively, are associated with AF.	15676170
Vasculitis, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Chronic vascular inflammation in patients with type 2 diabetes: endothelial biopsy and RT-PCR analysis.	15677796
Vasculitis, Cardiac complication, diabetic	Altered Intercellular Communication	Chronic vascular inflammation may play a role in the development of macrovascular complications in diabetic patients.	15677796
Vasculitis, Cardiac complication, Diabetes Mellitus	Altered Intercellular Communication	Induction of RAGE and MCP-1 transcripts in patients with diabetes supports a role of chronic vascular inflammation in macrovascular complications.	15677796
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Cerebral inflammation as well as systemic immunological alterations have been reported in Alzheimer's disease (AD).	15677865
Inflammation, Confusion, Granuloma	Altered Intercellular Communication	To avoid confusion with nonspecific cases of lipogranulomatous inflammation, the terms "ointment granuloma" or "orbital paraffinoma" should be used to refer to patients presenting with orbital/eyelid lesions caused by ointment use.	15677949
Inflammation, Low Vision	Altered Intercellular Communication	Excision was attempted in case 1, but only piecemeal removal was achieved, leading to extensive postoperative inflammation and decreased vision.	15677950
Conjunctivitis	Altered Intercellular Communication	The GPC specimens did have a statistically significant increase in conjunctival inflammation and mucous strands on all three sample areas.	15677951
Granuloma, Inflammation, Exudate	Altered Intercellular Communication	In the secondary biopsy specimens, 2 patients in group 1 had polypoid granulation tissue, 1 patient had pyogenic granuloma, and 3 patients had exudate reflecting acute inflammation.	15677954
Inflammation	Altered Intercellular Communication	In group 2, granulation tissue was observed in 1 case, and 2 patients had acute inflammation.	15677954
Inflammation, atherosclerotic	Altered Intercellular Communication	Smoking increases inflammation and metalloproteinase expression in human carotid atherosclerotic plaques.	15678248
Inflammation, atherosclerotic, Destruction of tissue	Altered Intercellular Communication	This study demonstrates that cigarette smoking increases markers of inflammation and tissue destruction in atherosclerotic plaques.	15678248
Atherogenesis, Inflammation, Thrombosis of blood vessel, Infectious agent	Altered Intercellular Communication	The possibility that infectious agents may trigger a cascade of reactions leading to inflammation, atherogenesis, and vascular thrombotic events has recently been raised.	15678255
Inflammation, Granuloma	Altered Intercellular Communication	Chronic non-specific inflammation without granuloma formation was seen in 46% skin biopsy specimens, 29% showed acute or chronic inflammation and tuberculoid granuloma formation was seen in 25%.	15679662
Inflammation, Granulation finding, Chronic osteomyelitis	Altered Intercellular Communication	Histopathologic analysis of biopsy material revealed abscess only in 5 cases, granulation tissue only in 6, abscess with granulation tissue in 4, granulation tissue with chronic osteomyelitis in 5, and chronic inflammation in 2.	15680641
ARCN1 gene, Inflammation	Altered Intercellular Communication	Enhanced levels of hyaluronan in lungs of patients with COPD: relationship with lung function and local inflammation.	15681498
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic inflammation and airway remodelling are characteristics of chronic obstructive pulmonary disease (COPD).	15681498
ARCN1 gene, Inflammation	Altered Intercellular Communication	HA levels in induced sputum from patients with COPD were measured and related to local inflammation.	15681498
ARCN1 gene, Inflammation	Altered Intercellular Communication	These data indicate a relationship between HA levels, local inflammation and severity of disease, and suggest enhanced breakdown of HA in the lungs of patients with COPD.	15681498
Inflammation, Lymphovascular Invasion 1	Altered Intercellular Communication	The lower prevalence and lack of prognostic significance of LVI in AEG I might be explained by inflammation involved in the pathogenesis of this entity.	15681533
Inflammation, Arthritis	Altered Intercellular Communication	Circulating CD26 is negatively associated with inflammation in human and experimental arthritis.	15681827
Intestinal metaplasia, Gastritis, Gastritis, Atrophic	Altered Intercellular Communication	Hematoxylin-eosin staining was used for the histological diagnosis of gastric mucosa inflammation, gastric glandular atrophy and intestinal metaplasia and scored into four grades according to the Updated Sydney System.	15682469
Helicobacter-associated gastritis	Altered Intercellular Communication	The purpose of the present paper was to assess the reproducibility of the (13)C-urea breath test ((13)C-UBT) and its ability to reflect the level of Helicobacter pylori-associated inflammation.	15683431
Inflammation, Gastritis	Altered Intercellular Communication	The (13)C-UBT results were significantly higher in symptomatic subjects with a moderate to severe gastritis compared to a mild gastritis and to no inflammation (34.5 +/- 4.4 vs 17.7 +/- 2.8 vs 1.7 +/- 0.1, respectively, P < 0.01).	15683431
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	conclusion: The (13)C-UBT is a reproducible determinant of H. pylori infection and non-invasively assesses the severity of antral inflammation.	15683431
Inflammation	Altered Intercellular Communication	Some of these mechanisms could increase risk (for example, inhibition of prostacyclin production), and some could decrease risk (for example, inhibition of inflammation).	15684203
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	EBC pH may be a biomarker of airway inflammation in chronic obstructive pulmonary disease (COPD).	15684290
Airway structure, Inflammatory disorder	Altered Intercellular Communication	Bronchoscopy with bronchoalveolar lavage (BAL) is an important research tool for assessing airway inflammation in a variety of inflammatory lung diseases.	15684291
Inflammation, Arteriosclerosis	Altered Intercellular Communication	Proliferative arteriosclerosis occurred with disease progression in the flexor tenosynovium, in the absence of inflammation.	15685708
Thrombosis	Altered Intercellular Communication	Inflammation-sensitive proteins and erythrocyte aggregation in atherothrombosis.	15686778
Communicable Diseases, Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation and infection have been implicated in atherosclerosis and its complications.	15686783
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a critical role in the pathogenesis of atherosclerosis.	15686784
Pain Distress Question, Inflammation	Altered Intercellular Communication	A 56-year-old female patient displayed an increased volume of her left lacrimal gland with pain and inflammation.	15687937
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	The presence of inflammation and intestinal metaplasia were documented.	15689086
Inflammation, Metaplasia	Altered Intercellular Communication	Imprint smears did not provide added value over histology with regards to inflammation and metaplasia.	15689086
Inflammation, Ascites	Altered Intercellular Communication	Sonography showed ascites in the region of the terminal ileum, and the presence of peritoneal nodules suggested peritoneal inflammation.	15690448
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	Characteristics of 34 consecutive patients undergoing liver transplantation for HBV cirrhosis were correlated with inflammation and immunohistological findings in the explanted livers.	15690540
Inflammation, Hepatitis	Altered Intercellular Communication	High-grade inflammation (grades 3 and 4) was found in many cases (47.1% interface hepatitis; 14.8% lobular inflammation; and 20.6% portal inflammation).	15690540
Decompensation, Inflammation	Altered Intercellular Communication	Patients with high-grade inflammation had greater degrees of hepatic decompensation.	15690540
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	In conclusion, high-grade inflammation is common in end-stage HBV cirrhosis, but it is not readily detected by biochemical and virologic parameters.	15690540
Decompensation, Inflammation	Altered Intercellular Communication	High-grade inflammation is associated with a greater degree of hepatic decompensation.	15690540
Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is an autoimmune disease characterised by chronic inflammation of the joints and is often associated with internal organs involvement.	15690700
Pain Distress Question, Inflammation, Traumatic injury	Altered Intercellular Communication	This group of medicines effectively blocks the prostaglandin synthesis in the course of pain and inflammation coupled with various injuries, tissue-lacerations.	15690916
Arthritis	Altered Intercellular Communication	Disruption of intestinal barrier function, followed by increased antigen load, may possibly trigger joint inflammation.	15693091
Inflammation, Spanish Language, Spondylarthritis	Altered Intercellular Communication	In seronegative spondyloarthritis (SpA) both gut inflammation and altered intestinal permeability have been reported.	15693091
Inflammation, Spanish Language	Altered Intercellular Communication	In SpA patients, GI permeability did not correlate with clinical activity or biochemical inflammation.	15693091
Inflammation, Exophthalmos	Altered Intercellular Communication	A 9-year old girl consulted for exophthalmia of the left eye without neither inflammation nor visual function alteration.	15693484
Vestibular dysfunction, Inflammatory abnormality of the eye, Inflammatory polyarthritis, Chondritis of pinna	Altered Intercellular Communication	At the age of 56, the patient was diagnosed with RP based on her symptoms, which included bilateral auricular chondritis, nonerosive seronegative inflammatory polyarthritis, and ocular inflammation, as well as vestibular dysfunction.	15694246
Adrenergic Agents, Inflammation, Thromboembolism	Altered Intercellular Communication	Adrenergia and inflammation are known to accompany these conditions, particularly among arterial thromboembolic disorders, but the teleologic basis of these associations remains poorly understood.	15694686
Inflammation	Altered Intercellular Communication	Molecular evidence suggests that adrenergia and inflammation can promote coagulation and lead to co-activation of the pathways.	15694686
Inflammation, Hypoxia, Thromboembolism	Altered Intercellular Communication	During acute thromboembolism, downstream tissue hypoxia can activate maladaptive self-propelling cycles of sympathetic bias, inflammation, and coagulation.	15694686
Inflammation, Primary malignant neoplasm, Thrombophilia	Altered Intercellular Communication	Unexplained hypercoagulability of cancer may also operate through tumor-induced adrenergia and inflammation.	15694686
Inflammation, Restenosis	Altered Intercellular Communication	Oxidative stress and inflammation in the vessel wall may play important roles in the development of restenosis after angioplasty.	15694802
Inflammation	Altered Intercellular Communication	Oxidative stress appears to be a key component of many reactions associated with chronic inflammation.	15694941
Inflammation, Pathology, Edema, Obesity	Altered Intercellular Communication	If we accept this notion of microvacuoles, then it becomes possible to explain certain pathologies occurring with age, such as edema, obesity, aging and inflammation.	15695007
Inflammation, Urethritis	Altered Intercellular Communication	Urethral inflammation was associated with higher sensitivities of urine LCR (86 compared to 70% when inflammation was absent) and PCR (82 compared to 62% when inflammation was absent).	15695648
Airway structure, Asthma	Altered Intercellular Communication	Our study has demonstrated that TNF-alpha and IL-1beta have the potential to modulate differentially the interactions between cells present in the inflamed airways of a patient with asthma and therefore to contribute to the regulation of airway inflammation and remodeling.	15696085
Inflammation, Thrombosis, Calcinosis, Myxoma	Altered Intercellular Communication	The individual patient cases of myxoma did not differ in location or clinical event in terms of pathological scores, such as vascular proliferation, inflammation, cellularity, hyaline, calcification, or thrombosis.	15696123
Lymphoma, Non-Hodgkin, Inflammation	Altered Intercellular Communication	Pyothorax-associated lymphoma (PAL) is non-Hodgkin's lymphoma that develops from chronic inflammation.	15696190
Sclerosis, Suppurative inflammation, Thickened	Altered Intercellular Communication	The lesions consisted of dystrophic modifications of the fingernails, progressive sclerosis, skin thickening and ulcerations on the fingers, acro-osteolysis, and purulent inflammation with subsequent auto-amputation of the distal phalanx of the right index finger.	15696265
Microalbuminuria, Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The results indicate that: (1) AER is the main independent predictor of 11-year cardiovascular mortality; (2) this effect is mainly evident in the upper range of microalbuminuria and in macroalbuminuria; and (3) fibrinogen has an independent effect on cardiovascular mortality, but no synergistic effect with AER, suggesting that both endothelial dysfunction and chronic inflammation are involved in the excess cardiovascular mortality of type 2 diabetic patients.	15696295
Inflammation, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	Inflammation and oxidative stress are established risk factors for atherosclerosis, but whether they contribute to the accelerated atherogenesis associated with chronic kidney disease (CKD) remains to be assessed at the predialysis stage.	15696442
Hormone abnormality, Lymphocytic hypopituitarism	Altered Intercellular Communication	Lymphocytic hypophysitis may involve the pituitary gland and various hormonal abnormalities.	15696461
Inflammation, Fatigue	Altered Intercellular Communication	Self-reported measures of disease activity and mental health contributed significantly to explain fatigue, whereas clinical measures of inflammation and joint mobility did not.	15696569
allergic inflammation	Altered Intercellular Communication	The close correlation was observed in upper and lower airway for allergic inflammation.	15696921
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	In the second cohort, the number of circulating endothelial cells was independent of all markers of inflammation and endothelial dysfunction.	15698448
Inflammation, Endothelial dysfunction, Cardiovascular system	Altered Intercellular Communication	In this hemodialysis population, an increase in circulating endothelial cells was found to predict the development of cardiovascular and vascular events, and to be independent of other known markers of inflammation or endothelial dysfunction.	15698448
Inflammation, Injury of liver, Intradermal Route of Drug Administration	Altered Intercellular Communication	However, in the presence of inflammation or liver injury, soluble transferrin receptor (sTfR) determination was proposed to replace ferritin for diagnosing iron deficiency (ID).	15698591
Myocarditis	Altered Intercellular Communication	Myocardial inflammation was assessed by histological and immunohistological analyses.	15699250
Inflammation, Acute suppurative inflammation	Altered Intercellular Communication	Elements of productive chronic inflammation accompanied by the tissue changes characteristic of acute purulent inflammation were found to be present.	15699974
Inflammation, Osteoporosis	Altered Intercellular Communication	Higher circulating hsCRP levels are associated with lower bone mineral density in healthy pre- and postmenopausal women: evidence for a link between systemic inflammation and osteoporosis.	15702263
Inflammation	Altered Intercellular Communication	These findings suggest that subclinical systemic inflammation may be associated with bone turnover rate and bone mass in healthy women.	15702263
Inflammatory abnormality of the eye	Altered Intercellular Communication	We report our experience with infliximab in chronic ocular inflammation as part of a retrospective review of all patients treated for chronic inflammatory ocular conditions seen over a 2-year period at our institution.	15704608
Inflammation, Inflammatory abnormality of the eye	Altered Intercellular Communication	All patients had persistent inflammation despite systemic immunosuppressive agents and all but one patient experienced marked improvement in ocular inflammation with infliximab.	15704608
Sarcoidosis	Altered Intercellular Communication	It is effective in several chronic inflammatory conditions, including sarcoidosis.	15704608
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	The resected gland in the first operation had clusters of lymphoid follicles with germinal centers indicating a chronic autoimmune inflammation.	15704665
Occluded, Sinusitis	Altered Intercellular Communication	This may have been caused by an ostium occlusion with retention of secretions inducing sinus inflammation, osteolytic activity, and osseous remodeling of the sinus walls.	15706991
Alzheimers Disease", Data types - Address, Nerve Degeneration	Altered Intercellular Communication	Neuropsychiatric symptoms seen in Alzheimer's disease (AD) are not simply a consequence of neurodegeneration, but probably result from differential neurotransmitter alterations, which some patients are more at risk of than others.	15707619
Airway structure	Altered Intercellular Communication	Involvement of tachykinins in airway inflammation has been demonstrated in animal models, but evidence in humans is sparse.	15707854
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	All patients were treatment naive and had chronic inflammation and fibrosis on biopsy.	15709027
Inflammation, Primary malignant neoplasm, Granulomatous disorder	Altered Intercellular Communication	Although PET is accurate for detecting cancer, increased 18 F-fluorodeoxyglucose (FDG) uptake can be seen in healthy tissues such as muscle, fat, and glands and uptake can be seen in tissues affected by inflammation or granulomatous disease.	15709148
Inflammation, Neoplasms, Candida (fungus)	Altered Intercellular Communication	[Adhesion of Candida to the obturator and oral mucosa as a cause of the presence of inflammation in patients treated surgically for neoplasia].	15709798
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Platelet-activating factor acetylhydrolase activity indicates angiographic coronary artery disease independently of systemic inflammation and other risk factors: the Ludwigshafen Risk and Cardiovascular Health Study.	15710755
Inflammation, Atherosclerosis	Altered Intercellular Communication	Platelet-activating factor acetylhydrolase (PAF-AH), also denoted as lipoprotein-associated phospholipase A2, is a lipoprotein-bound enzyme that is possibly involved in inflammation and atherosclerosis.	15710755
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	PAF-AH activity is not an indicator of the systemic inflammation that accompanies acute coronary syndromes.	15710755
Interstitial Cystitis, Cystitis	Altered Intercellular Communication	We know that bladder inflammation has been noted in some patients with interstitial cystitis (IC).	15711286
Hepatitis, Fulminant Hepatitis	Altered Intercellular Communication	OPN expression is an important marker of the degree of liver inflammation, and its regulation mechanism is very important to understanding the pathophysiology of fulminant hepatitis.	15712659
Inflammation, Vegetation, Valvular stenosis, Calcified (qualifier), Bacterial Endocarditis	Altered Intercellular Communication	To better define the histological criteria for infective endocarditis, we used quantitative image analysis to compare these 2 groups of patients with respect to valvular fibrosis, calcifications, vegetations, patterns of inflammation, and vascularization.	15714409
Vegetation, Endocarditis	Altered Intercellular Communication	When no microorganisms are detected and vegetations are lacking in tissue adjacent to a mechanical valve, neutrophil-rich inflammation and extensive neovascularization might better histologically define the term "active endocarditis" in the Duke criteria.	15714409
ARCN1 gene, Chronic Obstructive Airway Disease, Exacerbation, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterised by airway inflammation, poor health status and recurrent infective exacerbations.	15715188
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The interrelationship between markers of inflammation and oxidative stress in chronic obstructive pulmonary disease: modulation by inhaled steroids and antioxidant.	15715193
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is accompanied by both airway and systemic inflammation and by oxidative stress.	15715193
Granulomatous inflammation, Traumatic injury, Neoplasms, Congenital Abnormality	Altered Intercellular Communication	The remaining cases were diagnosed as dacryolithiasis (62 cases; 7.9%), tumour (29 cases; 4.5%), trauma (19 cases; 3.0%), congenital malformation (nine cases; 1.4%), canaliculitis (eight cases; 1.2%) and granulomatous inflammation (eight cases; 1.2%).	15715565
Inflammatory, Inflammation, Neoplasms	Altered Intercellular Communication	Histopathology is necessary to confirm suspected tumours, more than half of which were inflammatory lesions, and to detect tumours that sometimes masquerade as inflammation.	15715565
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	The monocyte chemotactic protein-3 (MCP3), on chromosome 17q11.2-q12, is a secreted chemokine, which attracts macrophages during inflammation and metastasis.	15715950
Mood Disorders	Altered Intercellular Communication	Degeneration of neurotransmitter systems other than dopamine might play a specific role in the occurrence of these affective disorders.	15716302
vascular inflammations, Edema	Altered Intercellular Communication	The main signs of early vascular inflammation observed were vessel wall thickness and oedema (six cases) and increased mural enhancement on postcontrast T1-weighted images (four cases).	15716321
Albrights hereditary osteodystrophy", Parathyroid Hormone Resistance	Altered Intercellular Communication	Pseudohypoparathyroidism associated with Albright's hereditary osteodystrophy was diagnosed by biochemical, hormonal and radiographic studies.	15716624
Inflammation, Fever, Pyrexia of unknown origin (excl puerperal)	Altered Intercellular Communication	Pyrexia of unknown origin (PUO) and suspected focal infection/inflammation are challenging medical problems.	15717194
Conjunctivitis, Squamous metaplasia	Altered Intercellular Communication	However the presence of conjunctival inflammation correlated with the existence of extensive squamous metaplasia (p < 0.001).	15717746
Cancer-related fatigue, Conjunctivitis	Altered Intercellular Communication	The severity of conjunctival changes in CRF patients on regular hemodialysis are not related to calcium deposition but to acute conjunctival inflammation.	15717746
Inflammation, Gastritis, Ulcer	Altered Intercellular Communication	To test the hypothesis that both COX-1 and COX-2 expression in human gastric mucosa is up-regulated in the presence of inflammation as seen in patients with gastritis and gastric ulcers.	15720413
Elastoid degeneration, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Six of 18 patients--that is, seven of 29 specimens of conjunctivochalasis demonstrated signs of elastosis or of chronic non-granulomatous inflammation.	15722309
Inflammation, IL13 gene	Altered Intercellular Communication	Nasal eosinophils display the best correlation with symptoms, pulmonary function and inflammation in allergic rhinitis.	15722636
Inflammation, Necrosis, Lymphocyte, Hyperkeratosis, Varicosity, Edema, Fibrous, Calcified (qualifier), Dermatitis, Atrophic, Abnormal degeneration	Altered Intercellular Communication	The histologic evaluation of the amputation specimen showed: 1) dermal edema, perivascular dermatitis, and epidermal hyperkeratosis; 2) subcutaneous chronic inflammation with subtotal replacement of the adipose lobules by fibrous tissue associated with thickening of the muscular fascia, implying the fasciitis-panniculitis reaction pattern; 3) atrophy, degeneration, necrosis, and focal calcifications of the skeletal muscles; 4) phlebosclerosis, phlebectasias and lymphocytic arteritis; and 5) increased cortical porosity of the bones.	15722813
Inflammation, Malignant tumour of parotid gland, Neoplasms, Adenolymphoma	Altered Intercellular Communication	Malignant parotid tumors showed significantly higher FDG uptake (standard uptake values [SUVs]) than both benign tumors and inflammation, except in Warthin's tumor (5.82 +/- 3.95 vs. 2.07 +/- 1.33; P <0.01).	15722820
Inflammation, Bacterial Infections	Altered Intercellular Communication	Procalcitonin is a specific marker of severe bacterial infections with systemic inflammation.	15723146
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	These indices were compared across the 3 study groups and within the patient groups with respect to presence of inflammation, fibrosis, and steatosis, as determined by histologic evaluation.	15723843
Inflammation, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Doppler sonography is sensitive to hemodynamic alterations resulting from inflammation and fibrosis, and if sonography is the study of choice to follow the progression of hepatitis, it will not be adequate without Doppler imaging.	15723843
Inflammation	Altered Intercellular Communication	The PHS may indicate the possibility of serious inflammation, and accurate diagnosis and appropriate treatment should be decided.	15723844
Laryngeal amyloidosis, Plasmacytoma, Chronic inflammation, Hematological Disease	Altered Intercellular Communication	We report 2 cases of laryngeal amyloidosis in which dense plasma cell infiltrates were found in the vicinity of the amyloid deposits; in view of this finding, we suspected a hematologic disease--plasmacytoma in particular: However, molecular genetic analysis did not demonstrate any light-chain restriction, indicating that the plasma cells were of polyclonal origin and therefore consistent with chronic inflammation.	15724743
Retinal Detachment, Inflammation, Foreign-Body Reaction, Necrosis	Altered Intercellular Communication	Histopathology confirmed a total retinal detachment, necrosis of the detached retina, inflammation, and foreign-body reaction in the Dacron mesh.	15725896
Inflammation	Altered Intercellular Communication	The complex skirt area may be predisposed to long-term inflammation.	15725896
Inflammation, Asthma, Atopy	Altered Intercellular Communication	Exhaled nitric oxide (FENO) has been proposed as a marker of asthmatic inflammation, but it is unclear whether FENO in clinical use selects patients primarily according to their atopic or asthmatic status.	15727577
Inflammation, atherosclerotic	Altered Intercellular Communication	In this review, we present new information suggesting that microbubble contrast-enhanced IVUS can measure activity and inflammation within atherosclerotic plaques by imaging vasa vasorum density.	15727733
Inflammation, Urinary tract infection, Atrophy of kidney	Altered Intercellular Communication	Its pathogenesis is unknown, although it is generally associated with aging, renal atrophy, and long-standing chronic inflammation or urinary tract infection.	15729179
Rheumatoid Factor, Fibrinoid necrotizing inflammation	Altered Intercellular Communication	Such IgG subclass profiles may influence the effector phases of the immunological conflict between ACPA and deiminated fibrin that takes place specifically in the rheumatoid synovium and therefore may play a critical role in the self-maintenance of rheumatoid inflammation.	15730401
Tissue damage, Juvenile rheumatoid arthritis, Orchitis, Immune-mediated	Altered Intercellular Communication	Juvenile rheumatoid arthritis (JRA) is an immune-mediated disease characterized by articular inflammation and subsequent tissue damage that may result in severe disability.	15730500
Inflammation, Damage	Altered Intercellular Communication	The genetically determined immune response and subsequent inflammation influence the degree of mucosal damage.	15730520
Inflammation	Altered Intercellular Communication	Adhesion molecules of the CD11 cluster play an important role in adherence of neutrophils to endothelial cells in inflammation.	15730520
Gastritis	Altered Intercellular Communication	The biological effect of genetic variants of CD11c in gastric inflammation needs further clarification.	15730520
Airway structure, ARCN1 gene, Asthma	Altered Intercellular Communication	IL-17 may play a role in the airway inflammation in both COPD and asthma.	15730730
Neoplasms	Altered Intercellular Communication	Cyclooxygenase 2 (COX-2) is an inflammation-associated enzyme involved in the pathogenesis of many solid tumors, but little is known about its presence and role in hematologic neoplasms.	15731178
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Synovial tissue inflammation in early and late osteoarthritis.	15731292
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	To compare selected immunohistological features of inflammation in synovial tissue from patients with early and late osteoarthritis (OA).	15731292
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Manifestations of inflammation in early OA were associated with increased expression of the NF-kappaB1 (p<0.001) and RelA (p = 0.015) subunits, and with increased COX-2 expression (p = 0.04).	15731292
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Increased mononuclear cell infiltration and overexpression of mediators of inflammation were seen in early OA, compared with late OA.	15731292
Behavior, Cholestasis, Pruritus, Fatigue	Altered Intercellular Communication	Some studies suggest that behavioral complications of cholestasis, such as fatigue and pruritus, may be associated with altered neurotransmission in the brain.	15731594
Inflammation, Necrosis	Altered Intercellular Communication	However, esophageal biopsy specimens from all three patients had the same histological pattern of severe inflammation and necrosis.	15731944
Inflammation, Secondary malignant neoplasm of lung, Bronchiectasis, Carcinoma of lung, Angiodysplasia, Lung diseases	Altered Intercellular Communication	22 suffered from benign lung diseases (angiodysplasia, inflammation, bronchiectasia) and 30 patients had lung cancer (lung metastases in two cases).	15731954
Orchitis	Altered Intercellular Communication	These patients quite often complain about difficulties in breathing through the nose as well as of recrudescent auricular inflammation.	15732785
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	It has been hypothesized that inflammation may trigger the multiformic fibrotic lesions found in the affected lung, and defects in the innate immune defense, including the complement, can predispose to pulmonary fibrosis.	15733500
Inflammation, DGCR2 gene	Altered Intercellular Communication	Recent evidence suggests that inflammation is one of the key factors in the etiology of IDD.	15733644
Inflammation, Reperfusion Injury	Altered Intercellular Communication	Reperfusion injury and inflammation associated with cardiac surgery are thought to be involved in its pathogenesis.	15734396
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Consumption of trans fatty acids is related to plasma biomarkers of inflammation and endothelial dysfunction.	15735094
Barrett Esophagus, Inflammation, Gastroesophageal reflux disease	Altered Intercellular Communication	These data illustrate how consistent corpus inflammation reduces acid secretion, which prevents Barrett's oesophagus among those with abnormal gastro-oesophageal reflux barriers.	15735156
Necrotizing granulomatous inflammation, Mycobacterium Infections	Altered Intercellular Communication	The histopathological examination showed chronic granulomatous inflammation with giant multinucleated cells, suggestive of mycobacterial infection, and recurrence of TB was considered.	15735542
Inflammation	Altered Intercellular Communication	Foci of bone were also found in association with extensive chronic inflammation.	15737039
ARCN1 gene, Inflammation	Altered Intercellular Communication	Although inflammation is present in all smokers, only a percentage of them develop COPD.	15738286
Tissue damage, Inflammation	Altered Intercellular Communication	Although apoptosis is essential for tissue homeostasis, increased apoptosis may cause tissue damage and inflammation.	15738287
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation is an early feature of asthma.	15738288
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide is a noninvasive marker of airway inflammation.	15738288
Vasculitis	Altered Intercellular Communication	In the histopathologic examination of skin and hypodermis biopsy there was an inflammatory infiltration of the adipose tissue without features of vessel inflammation (the Weber-Christian syndrome).	15738595
Pain Distress Question, Neoplasms, Discogenic pain, Intervertebral Disk Displacement, Pain, Referred, Carpal Tunnel Syndrome, Pudendal Nerve Entrapment Syndrome, Spinal stenosis of lumbar region, Fracture, Sacroiliitis	Altered Intercellular Communication	After performing MR neurography and interventional MR imaging, the final rediagnoses included the following: piriformis syndrome (67.8%), distal foraminal nerve root entrapment (6%), ischial tunnel syndrome (4.7%), discogenic pain with referred leg pain (3.4%), pudendal nerve entrapment with referred pain (3%), distal sciatic entrapment (2.1%), sciatic tumor (1.7%), lumbosacral plexus entrapment (1.3%), unappreciated lateral disc herniation (1.3%), nerve root injury due to spinal surgery (1.3%), inadequate spinal nerve root decompression (0.8%), lumbar stenosis (0.8%), sacroiliac joint inflammation (0.8%), lumbosacral plexus tumor (0.4%), sacral fracture (0.4%), and no diagnosis (4.2%).	15739520
Inflammation, Spondylitis, Collagen Diseases	Altered Intercellular Communication	Ankylosing spondylitis (AS) is a rheumatic disease characterized by consolidation of the articulating surfaces and inflammation of the vertebral column.	15739538
Inflammation	Altered Intercellular Communication	Even though H. pylori itself induces expression of RANTES, at the transcriptional level, genetic variations leading to higher transcriptional activity do not modify the degree of inflammation.	15740484
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Genotype B patients were older, had earlier HBeAg seroconversion and exhibited more severe lobular necroinflammation, less portal inflammation and fibrosis than genotype C patients.	15740490
Schistosomiasis japonica, Inflammation, Actual blood loss, Anemia	Altered Intercellular Communication	It is likely that occult blood loss plays a role only at heavier intensity S. japonicum infections and some other mechanism, such as anemia of inflammation, may be contributing to anemia.	15741543
Intestinal metaplasia, Gland, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Hematoxylin-eosin staining was used for the histological diagnosis of activity of H pylori infection, mucosal inflammation, glandular atrophy and intestinal metaplasia and scored into four grades according to the Updated Sydney System.	15742399
Gastritis, Infection caused by Helicobacter pylori, Gastric Ulcer, CTCAE 5, Gland, Intestinal metaplasia, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Total rate of H pylori infection, mucosal inflammation, activity of H pylori infection, glandular atrophy and intestinal metaplasia in 3 839 gastric ulcer patients (78.5%, 97.4%, 82.1%, 61.1% and 64.2%, respectively) were significantly higher than those in 4 102 chronic gastritis patients (55.0%, 90.3%, 56.2%, 36.8%, and 37.0%, respectively, P<0.05).	15742399
Inflammation, Stenosis, Neoplasms	Altered Intercellular Communication	Surgical procedures were chosen for these three patients, while balloon dilation was chosen for the strictures in four patients diagnosed with inflammation without involvement of neoplasm.	15742422
Arthritis	Altered Intercellular Communication	Overexpression of osteopontin in rheumatoid synovial mononuclear cells is associated with joint inflammation, not with genetic polymorphism.	15742430
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	We investigated the expression of OPN in rheumatoid synovial fluid mononuclear cells (SFMC) and its potential association with genetic polymorphism of the OPN gene and joint inflammation in rheumatoid arthritis (RA).	15742430
Inflammation, Atherosclerosis, Refractory anemias, Hypothyroidism, Hypertension, CTCAE	Altered Intercellular Communication	Atherosclerosis in RA is associated with the traditional CV risk factors age and hypertension, as well as nontraditional risk factors comprising current inflammation as reflected by polymorphonuclear cell counts, cumulative inflammation as disclosed by radiographic scores, and, to a lesser extent, with uric acid levels and hypothyroidism.	15742434
Carcinoma, Ulcerative Colitis	Altered Intercellular Communication	Although a chronic inflammation-carcinoma sequence has been proposed in cases of longstanding ulcerative colitis (UC), the relationship of morphological alteration or remodeling of regenerated mucosa to carcinoma development is yet to be clarified.	15743319
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Accumulated damage to DNA, reflected by increased p53 and p21(WAF1) labeling indices, might be involved in cancer development, as well as longstanding inflammation.	15743319
Inflammation, Spanish Language, Synovitis, Refractory anemias, Spondylarthritis, Rheumatoid Arthritis	Altered Intercellular Communication	Considering the relation between synovial inflammation and global disease activity in rheumatoid arthritis (RA) and the distinct but heterogeneous histology of spondyloarthropathy (SpA) synovitis, the present study analyzed whether histopathological features of synovium reflect specific phenotypes and/or global disease activity in SpA.	15743484
Inflammation	Altered Intercellular Communication	Varying degrees of inflammation can be present in the gastric mucosa of patients infected with H. pylori.	15744498
Inflammation, Giant Cells, Langhans, Caseous necrosis, Neoplasms	Altered Intercellular Communication	Histopathology of the tumor demonstrated chronic inflammation, caseous necrosis, epithelioid cells and Langhans' giant cell.	15744852
Ischemia, Microembolus, Inflammation	Altered Intercellular Communication	During cardiopulmonary bypass (CPB), the brain and the kidneys may be damaged because of microemboli, ischemia, and inflammation.	15745143
Eosinophilic inflammation	Altered Intercellular Communication	Eosinophil infiltration may be considered characteristic of nasal allergic inflammation.	15745370
Inflammation, Hyperreactivity, Allergic	Altered Intercellular Communication	We investigated the relationship between inflammation, specific hyperreactivity and clinical late phase reactions in allergic subjects using the ASNC model.	15745370
House dust mite allergy, Inflammation	Altered Intercellular Communication	Therefore, in house dust mite allergy minimal persistent inflammation without symptoms can drive different clinical responses to allergen challenge.	15745370
Inflammation, Vegetation	Altered Intercellular Communication	The specificity of histology was also of 100% (118/118) when using stringent criteria (ie, presence of vegetation, microorganisms, and/or valvular inflammation with mainly polymorphonuclear cells).	15745720
Unknown (origin) (qualifier value), Intraocular inflammation, Uveitis	Altered Intercellular Communication	Inclusion criteria were idiopathic, active intraocular inflammation, uveitis as a primary process and no systemic anti-inflammatory treatment at the time of blood sampling.	15746567
Pancreatitis	Altered Intercellular Communication	In the operative treatment of chronic pancreatitis, partial pancreatectomy is superior to vessel ligation, depending on the patient's general condition and degree of pancreatic inflammation.	15746787
Inflammation, Nasal Polyps	Altered Intercellular Communication	Final histopathology of the remaining 866 (99.8%) specimens was consistent with inflammation and/or nasal polyposis.	15746852
Inflammation	Altered Intercellular Communication	Inclusion criteria consisted of a positive diagnosis with pathologic tissue confirmation of chronic inflammation.	15746854
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Dermo-epidermal cleavage, fibrosis and inflammation are the main histological findings.	15748558
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	The importance of the role of inflammation has been suggested in the pathogenesis of Alzheimer's disease (AD).	15748779
Chronic heart failure	Altered Intercellular Communication	Neurohormones as markers of right- and left-sided cardiac dimensions and function in patients with untreated chronic heart failure.	15749191
Coughing, Idiopathic Pulmonary Fibrosis, Airway structure	Altered Intercellular Communication	We tested the hypothesis that the cough and increased cough reflex sensitivity seen in patients with idiopathic pulmonary fibrosis may be due to airway inflammation in a prospective, cross-sectional study.	15750711
Airway structure, Coughing, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Idiopathic pulmonary fibrosis is characterised by the presence of active eosinophilic airway inflammation raising the possibility that airway inflammation may contribute to symptoms such as cough.	15750711
Rheumatoid Arthritis, Arthritis, Synovitis	Altered Intercellular Communication	A novel ultrasonographic synovitis scoring system suitable for analyzing finger joint inflammation in rheumatoid arthritis.	15751062
Refractory anemias, Rheumatoid Arthritis, Arthritis, Synovitis	Altered Intercellular Communication	To develop an ultrasonographic (US) synovitis scoring system suitable for evaluation of finger joint inflammation in patients with active rheumatoid arthritis (RA) and to compare semiquantitative US scoring with quantitative US measurements.	15751062
Refractory anemias, Inflammation, Rheumatoid Arthritis, Cardiovascular system	Altered Intercellular Communication	To determine whether systemic inflammation confers any additional risk for cardiovascular death among patients with rheumatoid arthritis (RA), after adjusting for traditional cardiovascular risk factors and comorbidities.	15751097
Inflammation, Complication Aspects, Refractory anemias, Rheumatoid Factor, Dyslipidemias, Congestive heart failure, Coronary heart disease, Diabetes Mellitus, Choline Dehydrogenase, Mitochondrial, Joint swelling, Hypertension, CTCAE, Disease	Altered Intercellular Communication	Detailed information on the occurrence of various cardiovascular risk factors (personal history of coronary heart disease [CHD], congestive heart failure, smoking, hypertension, dyslipidemia, body mass index [BMI], diabetes mellitus, menopausal status) as well as indicators of systemic inflammation and RA disease severity (rheumatoid factor [RF] seropositivity, erythrocyte sedimentation rate [ESR], joint swelling, radiographic changes, RA nodules, RA complications, RA treatments, disease duration) and comorbidities were collected on all subjects.	15751097
Refractory anemias, Inflammation, Cardiovascular system	Altered Intercellular Communication	These results indicate that markers of systemic inflammation confer a statistically significant additional risk for cardiovascular death among patients with RA, even after controlling for traditional cardiovascular risk factors and comorbidities.	15751097
Inflammation	Altered Intercellular Communication	Artificial surfaces are bioincompatible and, thus, may initiate a reaction similar to an acute inflammation.	15751665
Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	As this reduction of anticoagulation significantly preceded the changes of inflammatory parameters in SIRS patients, we think that a hypercoagulatory state, especially in cases of ongoing inflammation, is an additional trigger of SIRS.	15751665
Inflammation, Thromboembolism	Altered Intercellular Communication	Thromboembolic complications was always related with inflammation of knee joint alloplasty in our own material.	15751720
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Acute myocardial infarction (AMI) is associated with inflammation.	15753219
Inflammation	Altered Intercellular Communication	TCH was strongly associated with inflammation, primarily nodules of B lymphocytes; some T cells and macrophage infiltration were also observed.	15753378
Airway structure, Respiratory Hypersensitivity	Altered Intercellular Communication	Airway hyperresponsiveness to hypertonic saline (HS) is associated with airway inflammation.	15753635
Inflammation, Atherosclerosis	Altered Intercellular Communication	It is well documented that inflammation plays a major role in the establishment and progression of atherosclerosis.	15754021
Granulomatous inflammation, Sarcoidosis, Granuloma	Altered Intercellular Communication	DNA of Propionibacterium acnes , which is now strongly suspected as the pathogen of sarcoidosis, was detected in the patient's glomerular mesangial cells; tubular epithelial cells, which were involved in granulomatous inflammation; and mononuclear cells in epithelioid granulomas by in situ hybridization.	15754281
Inflammation	Altered Intercellular Communication	S-PIIINP decreased significantly in group A. Inflammation decreased in both groups, 34% in group A (P = .02), but only 10% in group B (P = NS).	15754377
lymphoblast, Inflammation	Altered Intercellular Communication	Pathology revealed lymphoblast infiltration and inflammation of respiratory mucosa.	15754783
Alzheimers Disease	Altered Intercellular Communication	Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities.	15755686
Infarction, Inflammation, Optic Neuritis, Unspecified visual loss	Altered Intercellular Communication	This case draws attention to the fact that optic neuritis may be an early inflammatory manifestation of WG and that rapid diagnosis and aggressive anti-inflammatory treatment is critical before inflammation of arteries leads to infarction and irreversible visual loss.	15756129
Inflammation	Altered Intercellular Communication	Regarding the primary outcome efficacy of inflammation control the assessment of cells did not differ (p=0.165), while flare in the anterior chamber was lowest (p=0.008) in the non-steroidal anti-inflammatory drug (NSAID) group.	15756571
Inflammation	Altered Intercellular Communication	Surface inflammation was lowest with prednisolone (p=0.002).	15756571
Cataract, Intraocular inflammation	Altered Intercellular Communication	Ketorolac tromethamine provides good control of intraocular inflammation after cataract extraction without the risk of a steroidal IOP increase, which was also not observed under rimexolone therapy.	15756571
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide is a marker of airway inflammation and it is significantly decreased by glucocorticosteroid therapy, especially in patients with asthma.	15757255
Asthma, allergic inflammation	Altered Intercellular Communication	Exhaled nitric oxide may indicate the intensity of allergic inflammation in patients with asthma.	15757255
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Previous studies have demonstrated inflammation to be a risk factor in patients with atrial fibrillation (AF).	15757607
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	Elevation of CRP and interleukin-6 suggest a role of inflammation in AF, and the relation of CRP and interleukin-6 to left atrial size and AF duration before cardioversion indicates that inflammation may participate in the process of atrial remodeling.	15757607
HD Term Type	Altered Intercellular Communication	Our results suggest that ghrelin, as well as AM, may play an important role as vasodilator local hormones and regulation of blood pressure during HD, especially the occurrence of EH.	15758554
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Alterations in the gamma-aminobutyric acid (GABA) neurotransmitter and receptor systems may contribute to vulnerability of hippocampal pyramidal neurons in Alzheimer's disease (AD).	15759131
Data types - Address	Altered Intercellular Communication	Thus, changes in hippocampal GBR1 may reflect alterations in the balance between excitatory and inhibitory neurotransmitter systems, which likely contributes to dysfunction of hippocampal circuitry in AD.	15759131
Alzheimers Disease", Data types - Address, Dementia, Vascular, VAD I protocol	Altered Intercellular Communication	Alzheimer's disease (AD) and vascular dementia (VaD) are both associated with deficits in cholinergic neurotransmission that are amenable to therapeutic intervention.	15760632
Rheumatoid Arthritis, Inflammation Mediators, Osteoporosis	Altered Intercellular Communication	To investigate the potential of a new osteogeometric technology based on digital X-ray radiogrammetry (DXR) as a diagnostic tool for quantification of severity-dependent osteoporosis, and to distinguish between inflammation-mediated and corticoid-induced variations of bone mineralisation in patients suffering from rheumatoid arthritis.	15761729
allergic inflammation, Disease	Altered Intercellular Communication	Eosinophilic cationic protein (ECP) and immunoglobulin E (IgE) are important mediators of allergic inflammation and they are commonly used in the diagnosis and follow-up of allergic diseases.	15763286
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The effect of aspirin on inflammation and oxidative stress, processes known to be involved in cardiovascular diseases, are not fully known.	15763433
Pain Distress Question, Inflammation	Altered Intercellular Communication	The sensation of pain arises from both central and peripheral sites, and inflammation may be one of its underlying causes.	15763605
Orbital Pseudotumor	Altered Intercellular Communication	During chemotherapy, she developed an unusual orbital inflammation.	15764119
Cirrhotic	Altered Intercellular Communication	In addition to the classic factor implicated in mortality (Child-Pugh class), alterations in inflammation-related components and soluble adhesion molecules, as representatives of hemodynamic alterations, are of prognostic significance in cirrhotic patients.	15764154
Tuberculosis of intestines, Colitis	Altered Intercellular Communication	Therefore, in cases of colonic inflammation, where intestinal tuberculosis is an important differential diagnosis, a more aggressive diagnostic approach such as explorative laparoscopy should be considered.	15764159
ARCN1 gene, Inflammation	Altered Intercellular Communication	These findings suggest that increased arterial Hb-CO may relate to severity in patients with COPD because of lung and systemic inflammation and production of reactive oxygen species.	15764730
Inflammation, Chronic sinusitis	Altered Intercellular Communication	Chronic rhinosinusitis is characterized by persistent inflammation of the nasal and paranasal mucosa with numerous emigrated leukocytes.	15764731
Inflammation	Altered Intercellular Communication	The severity of the inflammation was determined by intraoperative endoscopic findings, computed tomography scans, and histopathologic assessment of the specimens.	15764731
Chronic maxillary sinusitis, Inflammation	Altered Intercellular Communication	Our results suggest that functionally active L-selectin ligands might guide leukocyte traffic into maxillary sinus mucosa preferentially in patients with severe findings of chronic maxillary rhinosinusitis, thus leading to aggravation of the inflammation.	15764731
airway disease, Inflammation, Parenchyma	Altered Intercellular Communication	Chronic inflammation causes small airway disease and parenchymal destruction, leading to the airflow limitation.	15766560
Acute inflammation	Altered Intercellular Communication	To report a case of an occult, metallic, anterior-chamber intraocular foreign body after uneventful phacoemulsification that was masquerading as chronic recalcitrant postoperative inflammation.	15767070
Inflammation, Macular Edema, Cystoid, Visual disturbance	Altered Intercellular Communication	A 73-year-old patient was referred to us for recalcitrant anterior-chamber inflammation after uneventful phacoemulsification; the patient presented with visual disturbances, anterior-chamber inflammation, and macular epiretinal membrane with concomitant cystoid macular edema.	15767070
Intraocular inflammation	Altered Intercellular Communication	However, in the absence of intraocular inflammation, surgical removal of such particles is questionable.	15767070
Lymphoma, Non-Hodgkin, Intraocular inflammation, Subretinal lesion	Altered Intercellular Communication	A 58-year-old woman with a history of treated systemic non-Hodgkin's lymphoma presented 2 years later with a subretinal lesion and intraocular inflammation in her left eye.	15767087
Lymphoma, Non-Hodgkin, Intraocular inflammation, Infiltration, Intraocular Lymphoma	Altered Intercellular Communication	We conclude that systemic non-Hodgkin's lymphoma can present remotely with findings resembling primary intraocular lymphoma and should be included in the differential diagnosis of intraocular inflammation and subretinal infiltrates.	15767087
Malignant tumor of colon, Inflammation	Altered Intercellular Communication	Prostaglandin H synthase 2 (PTGS2) or cyclooxygenase-2 (COX-2) has been shown to play a key role in the regulation of inflammation, and its inhibition is associated with a reduced risk of colon cancer.	15767339
Inflammation, atherosclerotic	Altered Intercellular Communication	Increasing evidence supports a role for inflammation in the atherosclerotic process.	15767524
Inflammatory Bowel Diseases, Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Observations that risk for colorectal cancer is elevated in patients with inflammatory bowel disease and that long-term use of anti-inflammatory drugs may reduce colorectal cancer risk have raised the possibility that inflammation may play a role in the development of colorectal cancer.	15767620
Malignant tumor of colon, Inflammation	Altered Intercellular Communication	While a recent prospective study observed a positive association between C-reactive protein (CRP), a marker of inflammation, and risk for colon cancer, data testing this hypothesis are sparse.	15767620
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Low-grade inflammation may not play an important role in increasing the risk for colorectal cancer.	15767620
Inflammation, Swelling	Altered Intercellular Communication	Two days after admission, an abdominal CT scan revealed blurring of the peripancreatic fat planes, inflammation and swelling of the pancreas, and a substantial amount of ascitic fluid in the left anterior pararenal space and pelvis.	15767733
Inflammation, Edema, Papillary cystitis	Altered Intercellular Communication	All lesions lacked prominent edema and inflammation seen in polypoid cystitis.	15767798
Granulomatous inflammation, Lymphoproliferative Disorders	Altered Intercellular Communication	Granulomatous inflammation, including NL, may be a cutaneous paraneoplastic expression of low-grade B-cell lymphoproliferative disease in the context of an underlying plasma cell dyscrasia.	15769274
Inflammation, Mucinous metaplasia, Traumatic injury, Genitalia	Altered Intercellular Communication	Mucinous metaplasia occurs uncommonly in cutaneous pathology, usually at specialized anatomic locations (genitalia, palms, and soles) and within restricted pathologic contexts (inflammation and trauma).	15769281
Refractory anemias, Inflammation, Impaired health, Joint deformity	Altered Intercellular Communication	We posited two distinct types of impairment in RA: 1) Joint inflammation, measured by the tender, painful and swollen joint counts; and 2) Joint deformity, measured by the deformed joint count.	15769287
Arthralgia, Grammatical Impairment, Sore to touch, Swelling	Altered Intercellular Communication	In the structural equation model, the joint inflammation impairment displayed a strong significant path toward the measured variables of joint pain, tenderness and swelling (standardized regression coefficients 0.758, 0.872 and 0.512, P	15769287
Inflammation	Altered Intercellular Communication	Both the joint inflammation and joint deformity impairments displayed strong direct paths toward functional limitation (standardized regression coefficients of -0.576 and -0.564, respectively, P	15769287
Refractory anemias, Arthritis, Joint deformity	Altered Intercellular Communication	This evidence supports the occurrence of two distinct impairments in RA, joint inflammation and joint deformity, that together, contribute strongly to functional limitations in this disease.	15769287
Inflammation	Altered Intercellular Communication	Transforming growth factor beta 1 (TGF beta 1) is a multifunctional cytokine that plays a key role in inflammation.	15769917
Abscess, Necrotic enterocolitis, Peritonitis, Inflammation of perianal region	Altered Intercellular Communication	The immune system deficiency in this cohort of patients may result in necrotic enterocolitis (leukemic typhlitis), perianal inflammation, abscesses, and peritonitis.	15771304
Inflammation, Dental Plaque	Altered Intercellular Communication	At the start and the end of each experimental period, the presence of plaque and gingival inflammation were recorded.	15771333
Inflammation, Dental Plaque	Altered Intercellular Communication	A significant improvement of plaque removal and reduction of the gingival inflammation over eight months were noticed for all three brushes (P < 0.05).	15771333
Inflammation, Hepatitis, Liver Cirrhosis, Pancreatitis Necrotizing	Altered Intercellular Communication	Histology showed acute necrotizing hepatitis in 19%, severe interphase hepatitis in 15%, chronic hepatitis with plasmo-lymphocytic infiltrate in 30%, cirrhosis in 29% (with active inflammation in one-third); biopsy was refused in 11%.	15771755
Communicable Diseases, Inflammation	Altered Intercellular Communication	All wounds healed uneventfully and were followed by a stable period without signs of pronounced inflammation or infection.	15772723
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	It has been poorly understood whether inflammation may contribute to atrial structural remodeling and increase the propensity for atrial fibrillation (AF) to persist.	15772777
Thrombosis of blood vessel, Inflammation	Altered Intercellular Communication	Biopsy results of both types of lesions revealed vascular thrombi without surrounding inflammation.	15773530
Vulvar Squamous Neoplasm, Inflammation, Hyperkeratosis	Altered Intercellular Communication	Results of histopathologic examination revealed a focal area of multinucleation in the basal to middle epithelial layers of the vulvar squamous epithelium, accompanied by mild hyperkeratosis and chronic inflammation.	15773533
Inflammation, Epithelial ovarian cancer, Anemia	Altered Intercellular Communication	Hemoglobin levels correlate with interleukin-6 levels in patients with advanced untreated epithelial ovarian cancer: role of inflammation in cancer-related anemia.	15774616
ovarian neoplasm, Inflammation, Anemia	Altered Intercellular Communication	This evidence suggests that anemia in epithelial ovarian cancer is common and its presence is related to stage of disease and markers of inflammation.	15774616
Hepatic inflammation, Leukopenia	Altered Intercellular Communication	Deficiencies in TPMT result in accumulation of toxic metabolites, followed by neutropenia and hepatic inflammation.	15776134
Multiple Myeloma, Atherosclerotic aneurysm, Aneurysm	Altered Intercellular Communication	Although it is unclear whether the lymphocyte infiltration in the aortic wall, which was denser than that of atherosclerotic aneurysm, was associated with multiple myeloma, the excessive aortic wall inflammation may have somewhat influenced aneurysm formation or aortic dissection.	15776306
Urine microscopy leukocytes present finding, Inflammation	Altered Intercellular Communication	Higher efficacy manifested with greater number of cases of leukocyturia elimination and conversion of cultivable mycobacteria into uncultivable ones, more obvious morphological signs of tuberculous inflammation involution.	15776824
Inflammation, Febrile Neutropenia, CTCAE	Altered Intercellular Communication	Assessment of systemic inflammation markers to differentiate a stable from a deteriorating clinical course in patients with febrile neutropenia.	15777341
ARCN1 gene, Inflammation, Airway Obstruction	Altered Intercellular Communication	Because the XO activity was significantly correlated with the degree of airway obstruction, these cytokine-XO production pathways may play a key role in the inflammation of COPD.	15777613
Inflammation, Spondylitis, Necrosis	Altered Intercellular Communication	Anti-tumour necrosis factor (TNF) treatment is clinically efficacious in patients with active ankylosing spondylitis (AS) and leads to improvement of spinal inflammation, as assessed by magnetic resonance imaging.	15778240
Inflammation, Pain Distress Question	Altered Intercellular Communication	In addition, topical methylprednisolone (1 mg/mL) was necessary to control inflammation and pain.	15778611
Granulomatous inflammation, Granuloma	Altered Intercellular Communication	Biopsy of subconjunctival nodules in the left eye failed to demonstrate granulomatous inflammation; however, a random conjunctival biopsy from the normal-appearing anophthalmic socket conjunctiva revealed noncaseating granulomas.	15778678
Inflammation, Atherosclerosis	Altered Intercellular Communication	The variation in MNDA expression appeared to change with phenotypic specialization of monocytes in atherosclerosis consistent with its association with inflammation and suspected roles in regulating gene expression or in mediating cell death.	15778972
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Two pathologists blinded to identifiers and clinical data independently scored the liver biopsies twice for portal fibrosis (PF: 0-6), lobular inflammation and necrosis (LIN: 0-3), Mallory bodies (MB: 0-3), hepatocyte ballooning (HB: 0-3), perisinusoidal fibrosis (PSF: 0-3) and fatty change (FC: 1-4).	15780053
Tubular atrophy, Interstitial Fibrosis Assessment, Interstitial inflammation, Glomerulosclerosis (disorder)	Altered Intercellular Communication	We retrospectively compared sonographic parameters (length, quantitative echogenicity, cortical thickness, and parenchymal thickness) to biopsy findings of glomerular sclerosis, tubular atrophy, interstitial fibrosis, and interstitial inflammation in 207 patients.	15780105
Tubular atrophy, Interstitial Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	By multivariate analysis, tubular atrophy and interstitial inflammation, but not interstitial fibrosis, were significant determinants of cortical echogenicity.	15780105
Inflammation, Calcification of coronary artery	Altered Intercellular Communication	Coronary artery calcification is highly prevalent in the hemodialysis population and is associated with older age, higher BMI, inflammation and reduced trabecular bone volume.	15780114
Inflammation, fibrogenesis, Pulmonary Fibrosis	Altered Intercellular Communication	Our findings suggest a pivotal role of PDGF signaling in the pathogenesis of pulmonary fibrosis and indicate that inhibition of fibrogenesis, rather than inflammation, is critical to antifibrotic treatment.	15781583
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	To assess the role of serum copper in relation to ceruloplasmin and other peripheral markers of inflammation in Alzheimer disease (AD).	15781823
Inflammation, Data types - Address	Altered Intercellular Communication	The authors found that copper (p < 0.001), peroxides (p = 0.026), and ceruloplasmin (p = 0.052) were increased and TRAP was decreased (p = 0.006) in patients with AD, while no other markers of inflammation were altered.	15781823
AURKAIP1 gene, Inflammation	Altered Intercellular Communication	While diffuse with same stage of inflammatory activity was observed in AIP, multifocal inflammation with different stage of inflammatory was seen in ACP.	15782107
AURKAIP1 gene, Inflammation, Fibrosis Assessment, NDUFAB1 gene	Altered Intercellular Communication	Fibrosis and inflammation are common to both AIP and ACP, but the pattern is very different between the 2 groups, and the deposition of collagen types III and IV is substantially different between AIP and ACP.	15782107
Inflammation	Altered Intercellular Communication	Diffuse inflammation in the spinal cord involving not only the pyramidal tract but also the anterior horn cells/intramedullary ventral roots explained the ALS-like clinical picture.	15782606
Neuritis, Inflammation	Altered Intercellular Communication	In these circumstances it is believed that a clinical neuritis, primary or secondary to a neighbouring inflammation may cause the start of this disorder.	15782648
Inflammation, Neoplasms	Altered Intercellular Communication	In multiple regression analysis, male gender, better tumor differentiation and greater tumor size, as well as the presence of acute inflammation were determined as significant independent predictors of the increased number of resected and examined lymph nodes.	15783001
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Whether homocysteine could participate in mucosal inflammation in inflammatory bowel disease (IBD) has not been explored yet.	15784037
Atherosclerosis	Altered Intercellular Communication	Our data implicate somatic DNA rearrangements, on loci associated to leukocyte adhesion, vascular smooth muscle cells growth, differentiation and migration, to atherosclerosis development as an inflammatory condition.	15784173
Hypersensitivity	Altered Intercellular Communication	Gigantomastia is a very rare entity of undetermined aetiology that may be due to hormonal imbalance, decreased hormonal catabolism or hypersensitivity of the target organ.	15784223
Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Inflammation, Hepatitis C, Chronic	Altered Intercellular Communication	Matrix metalloproteinases 2 and 9 are markers of inflammation but not of the degree of fibrosis in chronic hepatitis C. The degree of liver fibrosis and inflammation is important in patients with chronic hepatitis C (CHC) in terms of therapy as well as prognosis.	15785038
Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	To assess liver and serum MMP-2 and -9 as markers of fibrosis and inflammation in patients with CHC.	15785038
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Activities of inflammation and fibrosis stage were determined by the Desmet score on a scale of 0-4.	15785038
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	No correlation between liver MMP activities and liver fibrosis or inflammation was observed.	15785038
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The associations between physical activity, inflammation, and coagulation markers, in people with metabolic syndrome: the ATTICA study.	15785301
Inflammation, Aortic valve disorder	Altered Intercellular Communication	Non-aneurysmal inflammation of the aorta in combination with aortic valve disease.	15786016
Inflammation, Rheumatic Fever, Fibrosis Assessment, Aortic Valve Stenosis, Aortitis, Coronary Artery Disease	Altered Intercellular Communication	A 61-year-old man presented with aortic valve stenosis, coronary artery disease in combination with rheumatic arthritis, peri-aortic inflammation and fibrosis with aortitis.	15786016
Inflammation, Periaortitis, Atherosclerosis, Aortitis	Altered Intercellular Communication	In the pathological literature this has been termed chronic periaortitis, while in the surgical literature, non-aneurysmal dilatation of the aorta associated with atherosclerosis and inflammation has been described as aortitis.	15786016
Proteinuria, Inflammation	Altered Intercellular Communication	Elevations in vWF, as well as being related to classical risk factors, are associated with increases in total proteinuria and low-grade inflammation.	15786817
Hormone abnormality, primary enuresis	Altered Intercellular Communication	A 9-year-old boy presenting with primary enuresis nocturna was discovered to harbour a large left adrenal mass which produced no hormonal abnormalities.	15787319
Inflammation	Altered Intercellular Communication	In BPH patients stromal, periglandular, glandular inflammations did not increase PSA levels.	15787334
Inflammation	Altered Intercellular Communication	Pathological examination showed the parenchymal distortion and chronic inflammation.	15788969
Inflammation, Ascites	Altered Intercellular Communication	The cytology of the aspirated ascites showed sings of acute inflammation.	15790480
Inflammation, Fatty degeneration	Altered Intercellular Communication	Histological disease activity was defined as the sum of ballooning, steatosis, and parenchymal inflammation scores.	15791619
Inflammation, Tissue Adhesions	Altered Intercellular Communication	Elective conversion occurred in 8 (7.6%) patients due to poor visualization of anatomy because of inflammation and adhesions.	15791971
Inflammation, Tissue Adhesions	Altered Intercellular Communication	Conversion is related to poor visualization of anatomy due to inflammation and adhesions.	15791971
Inflammation, atherosclerotic	Altered Intercellular Communication	Inflammation is a key process in atherosclerotic formation.	15792679
Inflammation, atherosclerotic	Altered Intercellular Communication	We hypothesized that adiponectin was associated with atherosclerotic vascular changes involved in inflammation.	15792679
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Adults with the metabolic syndrome show biochemical evidence of low-grade inflammation.	15793189
Inflammation, Acute edema, Urticaria	Altered Intercellular Communication	Delayed resorption of the acute edema and prolonged inflammation were shown by laser Doppler flowmetry and 20-MHz ultrasound in the affected skin areas in patients with MM after induction of immunologic contact urticaria by a cosmetic ingredient.	15793508
Inflammation, Urticaria	Altered Intercellular Communication	We conclude that recurrent and possibly subclinical inflammation caused by immunologic contact urticaria in conjunction with a locally pre-existing lowered lymphatic drainage plays a crucial role in the evolution of MM.	15793508
Inflammation, Primary malignant neoplasm, Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	The risk of lymph node metastasis included histologic grade (P = 0.005), lymphatic vessel invasion (P = 0.023), inflammation around cancer (P = 0.049), and budding at the invasive front of tumor (P = 0.022).	15793641
Inflammation	Altered Intercellular Communication	Eosinophil-fibroblast interaction is an important event of persistent inflammation in airways.	15794076
Inflammation, Cerebral atrophy	Altered Intercellular Communication	The present study suggests that brain atrophy, correlating with disease duration and disability, is directly related to NAWM and T2-lesional inflammation as measured by microglial activation.	15794383
Proctitis, Gastrointestinal symptom	Altered Intercellular Communication	Colorectal inflammation is well predicted by fecal calprotectin in children with gastrointestinal symptoms.	15795593
Proctitis	Altered Intercellular Communication	In children with colorectal inflammation (n = 22) the median fecal calprotectin concentration was 349 microg/g (range, 15.4-1860 microg/g).	15795593
Proctitis, Gastrointestinal symptom	Altered Intercellular Communication	Increased fecal calprotectin strongly predicted the presence of colorectal inflammation in children with gastrointestinal symptoms.	15795593
Proctitis, Inflammatory Bowel Diseases	Altered Intercellular Communication	Fecal calprotectin can be used to select patients who should undergo diagnostic colonoscopy for investigation of colorectal inflammation, including inflammatory bowel disease.	15795593
Inflammation, Exudate	Altered Intercellular Communication	The inflammation of the arachnoid mater may produce a fibrinous exudate around the roots that causes them to adhere to the dural sheath.	15797502
Airway structure	Altered Intercellular Communication	Interestingly, DRS(HS) correlated positively with recipient:donor total lung capacity ratio (r = 0.5, p < 0.05), but there was no relationship between either challenge result and airway inflammation.	15797754
Chromosome 20, trisomy, Mosaicism, Congenital Growth Hormone Deficiency	Altered Intercellular Communication	We report a case of Ito-type pigmentary mosaicism associated with a congenital growth hormone deficiency having revealed trisomy 20 mosaicism.	15798568
Abscess, Phlegmon, Inflammation, Necrosis	Altered Intercellular Communication	Clinical-laboratory and bacteriological assessment showed that in local application of antibiotic-containing Supersorbicid in the complex treatment of abscesses and phlegmon of maxillo-facial region liquidation of local and common signs of inflammation was faser and corbent accumulated microbes and their toxins and the wound cleaning from necrotic mass was faser that resulted in acceleration of wound healing by secondary adhesion.	15798751
Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	The role of inflammation in acute coronary syndrome (ACS) and the mechanism by which statin treats ACS is explored.	15799170
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation plays an important role in the initiation of ACS.	15799170
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	Inflammation in amyotrophic lateral sclerosis spinal cord and brain is mediated by activated macrophages, mast cells and T cells.	15799549
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	Our data suggest that inflammation in ALS spinal cord and cortex is based on innate immune responses by macrophages and mast cells and adaptive immune responses by T cells.	15799549
Acute inflammation	Altered Intercellular Communication	No patient had pre-existing risk factors for increased postoperative inflammation and all received a one-piece polymethylmethacrylate intraocular lens placed in-the-bag.	15799742
Inflammation, Esophageal carcinoma	Altered Intercellular Communication	Serum parathyroid hormone-related peptide is associated with systemic inflammation and adverse prognosis in gastroesophageal carcinoma.	15800880
Inflammation, Hypercalcemia, CTCAE, Esophageal carcinoma	Altered Intercellular Communication	Elevated serum cPTHrP levels were present in approximately 17% of patients with gastroesophageal carcinoma in the absence of hypercalcemia and was associated with markers of systemic inflammation and with an adverse prognosis.	15800880
Inflammation, Esophageal carcinoma	Altered Intercellular Communication	Serum parathyroid hormone-related peptide is associated with systemic inflammation and adverse prognosis in gastroesophageal carcinoma.	15800880
Colonic Diverticulitis, Inflammation	Altered Intercellular Communication	On the basis of ultrasonography, we defined and categorized mild-to-moderate acute colonic diverticulitis ranging from limited inflammation within diverticulum to an abscess < 2 cm in diameter.	15801924
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a major role in the development and complications of atherosclerosis.	15802336
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Airway inflammation during stable and acutely exacerbated chronic obstructive pulmonary disease.	15802337
Airway structure	Altered Intercellular Communication	The aim of this study was to clarify the mechanism of increased airway inflammation during an acute exacerbation.	15802337
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	These findings suggest that exacerbation of chronic obstructive pulmonary disease may associate with additional increases in airway inflammation mediated by neutrophils, lymphocytes, eosinophils, interleukin-8 and RANTES.	15802337
Inflammatory Bowel Diseases, Inflammation, Osteoporosis	Altered Intercellular Communication	There is a potential interface between osteoporosis and the chronic inflammation of inflammatory bowel disease (IBD), and the osteoprotegerin (OPG)/receptor for activated nuclear factor-kappaB (RANK)/RANK ligand (RANKL) signaling pathway may be an important mediator, although data are limited.	15803021
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Clinical course of distal ulcerative colitis in relation to appendiceal orifice inflammation status.	15803026
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Although appendiceal orifice inflammation (AOI) is frequently observed as a skip lesion of ulcerative colitis (UC), its clinical significance is not clearly understood.	15803026
Colitis	Altered Intercellular Communication	Correct grading of colonic inflammation was performed with 55.1% sensitivity and 98.2% specificity in all segments.	15803030
Inflammation	Altered Intercellular Communication	Considering only more extensive inflammation (grade 2), the sensitivity of MRC increased to 70.2% with a specificity of 99.2%.	15803030
Inflammation, Hypoadiponectinemia, Metabolic Syndrome X	Altered Intercellular Communication	Low-grade systemic inflammation, hypoadiponectinemia and a high concentration of leptin are present in very young obese children, and correlate with metabolic syndrome.	15803114
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Inflammation and adipocytokines can play an important role in the etiopathogeny of metabolic syndrome.	15803114
Inflammation, Uveitis	Altered Intercellular Communication	Combined orbital floor injection of betamethasone and methylprednisolone can result in improved visual acuity, symptoms, and signs of inflammation in uveitis, and may therefore avoid the necessity for increased systemic medication.	15804765
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Haemophilus influenzae from patients with chronic obstructive pulmonary disease exacerbation induce more inflammation than colonizers.	15805181
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease, Exacerbation	Altered Intercellular Communication	Airway infection with Haemophilus influenzae causes airway inflammation, and isolation of new strains of this bacteria is associated with increased risk of exacerbations in patients with chronic obstructive pulmonary disease (COPD).	15805181
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	To determine whether strains of H. influenzae associated with exacerbations cause more inflammation than strains that colonize the airways of patients with COPD.	15805181
Airway structure, Exacerbation	Altered Intercellular Communication	The results indicate that H. influenzae strains isolated from patients during COPD exacerbations often induce more airway inflammation and likely have differences in virulence compared with colonizing strains.	15805181
Airway structure, Exacerbation	Altered Intercellular Communication	These findings support the concept that bacteria infecting the airway during COPD exacerbations mediate increased airway inflammation and contribute to decreased airway function.	15805181
Sinusitis, Craniosynostosis	Altered Intercellular Communication	IL-6, IL-8, and IL-11 are nonspecific markers of sinus inflammation being transcribed in patients with CRS and patients with CRS/NP.	15805881
Airway structure	Altered Intercellular Communication	The patient has evidence of airway inflammation and remodeling based on biomarkers and biopsy findings.	15805987
Airway structure	Altered Intercellular Communication	Biomarkers of airway inflammation such as exhaled nitric oxide, exhaled breath condensates, and induced sputum analysis may have the potential to monitor disease progression.	15805987
Airway structure, Bronchoconstriction	Altered Intercellular Communication	Treatment with inhaled steroids is an effective method of reducing bronchoconstriction and airway inflammation after allergen challenge.	15805993
Inflammation, Cardiac valve calcification	Altered Intercellular Communication	Association of cardiac valve calcification and inflammation in patients on hemodialysis.	15807189
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Enhanced TGFbeta1 production in the colonic mucosa of UC patients can not inhibit proinflammatory cytokine production and hence can not get control of inflammation; this finding suggests the possible presence of TGFbeta1 signaling defects in the cases of UC.	15807267
vascular inflammations	Altered Intercellular Communication	Reduction in vascular inflammation may be associated with reduced vascular risk.	15807879
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Cytokines play a central role in oral mucosal inflammation.	15809209
Inflammation, Platelet aggregation test result, SLC22A5 gene, Vaso-Occlusive Crisis	Altered Intercellular Communication	This facilitates inflammation, leukocyte adhesion, platelet aggregation and vaso-occlusion in SCD.	15809883
Inflammation, Lumbar disc disease	Altered Intercellular Communication	Can E-selectin be a reliable marker of inflammation in lumbar disc disease?	15809889
Inflammation, Intervertebral Disk Displacement	Altered Intercellular Communication	Inflammation has been shown to occur via immunohistochemical and biochemical methods in herniated disc tissues.	15809889
Inflammation, Intervertebral Disk Displacement	Altered Intercellular Communication	In our study, we aimed to show the role of E-selectin as an inflammatory marker and the correlation of inflammation with straight-leg raise (SLR) test findings and subtype of disc herniation.	15809889
Tissue damage, Inflammation, Autoimmune Chronic Hepatitis	Altered Intercellular Communication	Synovial macrophages play a pivotal role in the pathogenesis of chronic autoimmune arthritis by contributing to local inflammation and tissue damage and are therefore a primary target for therapeutic intervention.	15809977
Inflammation, Thrombus, Hyperviscosity syndrome	Altered Intercellular Communication	Although patients with BD show a moderate hyperviscosity syndrome, possibly related to chronic inflammation, this does not seem to play a role in the development of thrombotic events.	15810159
Inflammation, Psoriasis	Altered Intercellular Communication	Disordered differentiation and hyperproliferation of keratinocytes with inflammation are the hallmarks of psoriasis.	15811089
Cataract, Inflammation	Altered Intercellular Communication	Review of sterile, postoperative, anterior segment inflammation following cataract extraction and intraocular lens implantation.	15812764
Cataract, Inflammation	Altered Intercellular Communication	To evaluate unexpected, acute intraocular anterior segment inflammation following uneventful cataract extraction by phacoemulsification and foldable posterior chamber intraocular lens (PCIOL) implantation.	15812764
Cataract, Acute inflammation	Altered Intercellular Communication	This retrospective study evaluated five cases of postoperative inflammation that occurred after cataract extraction with foldable PCIOL implantation.	15812764
Acute inflammation	Altered Intercellular Communication	Medical records were reviewed to analyze the unexplained postoperative inflammation.	15812764
Unknown (origin) (qualifier value), Inflammation, Autoimmune hemolytic anemia	Altered Intercellular Communication	Idiopathic sclerosing inflammation of the orbit: a case of steroid-responsive disease in a patient with auto-immune hemolytic anemia.	15812770
Orbital Pseudotumor	Altered Intercellular Communication	Idiopathic sclerosing orbital inflammation (ISOI) has been categorized by some authors as a unique clinicopathologic entity, separate from the heterogeneous group of disorders known collectively as nonspecific orbital inflammation.	15812770
Infiltrate of cornea, Inflammatory abnormality of the eye	Altered Intercellular Communication	At 7 months of follow-up, the right eye showed no ocular inflammation, a reduction of the lipid-like peripheral corneal infiltrates, an increased stromal thickness, and an unchanged BCVA.	15812773
Inflammation	Altered Intercellular Communication	Conjunctival peritomy associated with AMT may be an alternative surgical approach in the management of Mooren's ulcers to control the inflammation and the progression of disease.	15812773
Inflammation, Respiratory Tract Infections, Bronchiectasis	Altered Intercellular Communication	Bronchiectasis is a chronic pulmonary process characterized by recurrent respiratory infections leading to destruction of airways secondary to inflammation.	15813663
Inflammation, Malnutrition	Altered Intercellular Communication	Old-old patients presented with laboratory data of malnutrition (decreased serum levels of albumin, cholesterol, hemoglobin, hematocrit, lymphocyte count) and inflammation (increased of transferrin and C-reactive protein).	15814166
Hepatitis, Chronic	Altered Intercellular Communication	We concluded that serum markers are valuable tools for investigating the complex effects of co-existing factors of chronic liver inflammation.	15814296
Inflammation	Altered Intercellular Communication	One possible hypothesis is that tumor-associated macrophages (TAM) act as the mediator that enables apoptosis of anti-tumor immune cells without FasL-related inflammation.	15816613
Seizures	Altered Intercellular Communication	Such hormonal changes might be relevant in seizure control and in patient health.	15816945
Inflammation	Altered Intercellular Communication	These findings suggest that activation of inflammation and haemostasis may be potential mechanisms by which cigarette and pipe/cigar smoking increase cardiovascular risk.	15817606
Inflammation, Spondylarthritis	Altered Intercellular Communication	Involvement of neurotrophins and their receptors in spondyloarthritis synovitis: relation to inflammation and response to treatment.	15817657
Inflammation, Spondylarthritis	Altered Intercellular Communication	To investigate whether expression of the four members of the neurotrophin (NT) family and their four corresponding receptors is related to synovial inflammation in patients with spondyloarthritis (SpA).	15817657
Inflammation	Altered Intercellular Communication	Their expression is not constitutive but related to inflammation and they may be involved in the local disease processes.	15817657
Inflammation, Chlamydia	Altered Intercellular Communication	Overexpression of MMP9 and tissue factor in unstable carotid plaques associated with Chlamydia pneumoniae, inflammation, and apoptosis.	15818457
vascular inflammations, Chlamydia, Dental Plaque	Altered Intercellular Communication	Moreover, interference of tissue remodeling by vascular inflammation, apoptosis, and Chlamydia pneumoniae inside plaque subregions is unclear.	15818457
Inflammation, Stenosis Morphology, Aneurysm	Altered Intercellular Communication	The inflammation of the arteries may lead to stenosis, occlusions, dilatations, and aneurysms of involved vessels.	15818512
Chronic periaortitis	Altered Intercellular Communication	To evaluate the presence and extent of large-vessel inflammation in patients with chronic periaortitis (CP) using (18)F-fluorodeoxyglucose-positron emission tomography (FDG-PET).	15818649
Inflammatory Bowel Diseases, Inflammation, Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	Fecal PMN-elastase and calprotectin support the differentiation of chronic IBD from IBS and correlate with the severity of inflammation.	15819166
Inflammation	Altered Intercellular Communication	These factors are probably present in chronic inflammation.	15819476
Inflammation, Coronary Artery Disease, Atherosclerosis	Altered Intercellular Communication	Physical activity may lower the risk for coronary artery disease (CAD) by mitigating inflammation, which plays a key role in the pathophysiology of atherosclerosis.	15820291
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Chronic low-grade inflammation response may contribute to the pathology of essential hypertension.	15820487
Inflammation	Altered Intercellular Communication	Increased NOX2 mRNA levels were observed in biopsies with signs of chronic inflammation (p=0.01).	15820617
ARCN1 gene, Inflammation	Altered Intercellular Communication	Relationships among bacteria, upper airway, lower airway, and systemic inflammation in COPD.	15821198
ARCN1 gene, Nasal inflammation	Altered Intercellular Communication	While upper airway symptoms are common in COPD patients, with accumulating evidence to suggest increased nasal inflammation, the relationships among upper airway, lower airway, and systemic inflammatory indexes have not been studied.	15821198
ARCN1 gene, Nasal inflammation, Airway structure	Altered Intercellular Communication	We aimed to confirm that there is heightened nasal inflammation in COPD patients, to test the hypothesis that the degree of upper airway inflammation relates to the degree of lower airway inflammation, and to investigate the underlying associations with bacterial carriage and the systemic inflammatory response.	15821198
Airway structure	Altered Intercellular Communication	We did not find significant relationships between the degree of upper or lower airway inflammation, or bacterial carriage, and the systemic inflammatory response.	15821198
Airway structure, ARCN1 gene	Altered Intercellular Communication	This study is the first to report a correlation between the degree of upper and lower airway inflammation in COPD.	15821198
Microalbuminuria, Organ Dysfunction Scores	Altered Intercellular Communication	The level of microalbuminuria is thought to reflect the severity of inflammation-induced systemic vascular permeability and may have prognostic value with regard to organ dysfunction and survival.	15821223
Inflammation, Stenosis, Traumatic injury	Altered Intercellular Communication	Inflammation was the cause of stricture in 83 (79%) and trauma the cause in 22 (21%) patients.	15821500
Inflammation, Periprosthetic osteolysis	Altered Intercellular Communication	FDG-PET is a promising, highly accurate examination method to detect polyethylene and metal wear-induced chronic inflammation followed by periprosthetic osteolysis.	15821896
Dermoid cyst of ovary, Granulomatous inflammation, Neoplasms	Altered Intercellular Communication	Pathologic examination in both cases showed ovarian mature cystic teratomas with peritoneal granulomatous inflammations response to the released tumor content.	15822552
Inflammation, Decidual endometritis, Endometritis, Necrosis, Infiltration	Altered Intercellular Communication	Three groups were distinguished: 1) abortions without inflammation; 2) cases with signs of moderate inflammation (endometritis, deciduitis); 3) cases with intensive inflammation with necrosis and leucocytic infiltration.	15822784
Inflammation, Atherosclerosis	Altered Intercellular Communication	Although it is suspected that low-grade inflammation as represented by increased C-reactive protein (CRP) plays an important role in the progression of atherosclerosis, it is not yet known whether serum CRP levels are associated with PWV.	15823292
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation is hypothesized to play a central role in atherogenesis, and serum markers of inflammation are predictive of cardiovascular disease.	15823291
Inflammation, atherosclerotic, Cerebrovascular accident	Altered Intercellular Communication	Serum inflammatory markers may provide a novel marker of atherosclerotic risk, and inflammation may provide a new therapeutic target for stroke prevention.	15823291
Airway structure	Altered Intercellular Communication	Sputum induction is a relatively non-invasive and safe method to study airway inflammation.	15823454
Communicable Diseases, Inflammation, Granulomatous disorder, Malignant Neoplasms	Altered Intercellular Communication	Idiopathic hypertrophic cranial pachymeningitis (IHCP) consists of meningeal thickening due to chronic inflammation for which no cause such as infection, specific granulomatous disease, or malignancy is demonstrable.	15823684
Inflammation, Thrombosis	Altered Intercellular Communication	With its homology with plasminogen, lipoprotein(a) [Lp(a)] may be related to thrombosis and inflammation.	15824077
Inflammation, Thrombosis, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Lp(a) levels >30 mg/dL are associated with twice the risk of CHD events among women and may be related to thrombosis and inflammation.	15824077
Inflammation, Neoplasms	Altered Intercellular Communication	Arachidonic acid and its metabolites elicit inflammation and promote tumor formation in mouse skin.	15824162
Inflammation	Altered Intercellular Communication	Muscle histopathology in four patients showed either end stage muscle or nonspecific myopathic findings without inflammation or vacuoles.	15824355
Pleurisy, Tuberculosis	Altered Intercellular Communication	Lymphocyte-dominant pleural inflammation is seen in tuberculous, malignant and immune-mediated pleural disease.	15824533
Inflammation, Lymphoproliferative Disorders	Altered Intercellular Communication	Whether these findings demonstrate an oligoclonal reaction to chronic inflammation or an emerging lymphoproliferative disorder must be elucidated in a long-term longitudinal study.	15825165
Colitis	Altered Intercellular Communication	To assess the basic clinicopathological information of colonic inflammation in Thai patients, the authors retrospectively analyzed the 249 biopsied cases with pathological diagnosis as colitis in King Chulalongkorn Memorial Hospital during the five-year period from 1998 to 2002.	15825713
Inflammation, Hemorrhagic infarct, Zygomycosis, Hemorrhagic, Acute infarct	Altered Intercellular Communication	At autopsy three organs were extensively involved by zygomycosis: (i) lungs were diffusely hemorrhagic with acute infarcts; (ii) pericardium had fibrotic inflammation; and (iii) the left cerebral hemisphere, cerebellum and pons had large hemorrhagic infarct by zygomycosis infection.	15826246
Chronic liver disease, Liver damage, Inflammation	Altered Intercellular Communication	Adiponectin is elevated in chronic liver disease and correlates with inflammation and liver damage.	15826715
Cerebellar Ataxia	Altered Intercellular Communication	However, the exact role of antiGAD-Ab and GABAergic neurotransmission in the pathogenesis of the neurological manifestations, particularly in progressive cerebellar ataxia, is not fully understood.	15826997
Inflammation, Neoplasms	Altered Intercellular Communication	Subsequent MRI demonstrated mild enhancement and could not differentiate between tumor versus inflammation.	15827406
Gastrointestinal inflammation	Altered Intercellular Communication	IL-6 sharply distinguishes between inflamed and non-inflamed mucosa, and is therefore a suitable marker of intestinal inflammation.	15827446
Inflammation, HD Term Type, Dentures, Depression, CTCAE, Anorexia, Uremia	Altered Intercellular Communication	Although it has been hypothesized that IDI might be secondary to uremia, anorexia, underlying illness, psychosocial conditions, loss of dentures, depression, aging, or chronic inflammation, definite data on the etiology of IDI in HD patients are still lacking.	15827898
methyldopa, Inflammation	Altered Intercellular Communication	Inflammation, oxidative damage, cholesterol metabolism and/or impaired function of retinal pigment epithelium (RPE) have been implicated in AMD pathogenesis.	15829498
Arteriosclerosis, Hypertension, CTCAE, Diabetes Mellitus, Cardiovascular system	Altered Intercellular Communication	It is suggested that renal production and urinary excretion of L-FABP are increased in situations in which arteriosclerosis is promoted, such as hypertension, diabetes mellitus, and cardiovascular inflammation.	15830271
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	Hepatic inflammation and fibrosis were less severe in the NBNC group than in the other groups.	15830287
Pneumonitis	Altered Intercellular Communication	The older infants were more likely to exhibit pulmonary and tracheal inflammation, and neuropathology.	15831009
Lymphoma	Altered Intercellular Communication	Several chronic inflammatory conditions are associated with an increased risk of lymphoma.	15831904
Airway structure, Asthma	Altered Intercellular Communication	Vascular endothelial growth factor (VEGF), AA isoform of platelet-derived growth factor (PDGF-AA), and epidermal growth factor (EGF) are involved in the pathogenesis of airway inflammation in asthma.	15832052
Pain Distress Question, Inflammation	Altered Intercellular Communication	The conclusions of the research underline the particular contribution of the clinical evaluation in diagnosis and the efficiency of external balneology in removing the pain and inflammation, maintaining the articular mobility and ability.	15832999
Inflammation, Appendicitis, CTCAE, Pathological Dilatation	Altered Intercellular Communication	Three independent blinded readers interpreted transverse scans alone and then coronal scans; confidence in visualization of any portion of appendix, entire appendix, wall thickening, distention, inflammation, fluid, and appendicitis was scored with 1-5 scale.	15833993
Inflammatory, Inflammatory abnormality of the eye	Altered Intercellular Communication	Onset and course of ocular inflammation, inflammatory signs, and visual acuity were assessed.	15834077
Inflammatory abnormality of the eye	Altered Intercellular Communication	Infliximab treatment resulted in an effective suppression of ocular inflammation in all patients.	15834077
Inflammatory abnormality of the eye, Behcet Syndrome, Vasculitis, CTCAE, Uveitis	Altered Intercellular Communication	Anti-TNF-alpha treatment may be of value in the treatment of uveitis, and in patients with Behcet's disease, leading to suppression of ocular inflammation, vasculitis, and improvement of vision in the majority.	15834077
Bacterial Infections, Conjunctivitis	Altered Intercellular Communication	Recurrent trichiasis was associated with severe conjunctival inflammation and bacterial infection.	15834088
Bacterial Infections, Conjunctivitis	Altered Intercellular Communication	The role of conjunctival inflammation and bacterial infection needs to be investigated further.	15834088
Inflammation	Altered Intercellular Communication	Pathogenic mechanism of acute and chronic inflammation is connected to the increased production of superoxide anion, hydrogen peroxide, and other free radicals.	15834183
Inflammation	Altered Intercellular Communication	Lymphatic-muscular system and its anatomical links and age-related changeability raise the special interest during odontogenic infections with tongue inflammation.	15834184
Sarcoma, Hematoma, Inflammation	Altered Intercellular Communication	The characteristics of FDG-PET images of chronic expanding hematomas, including the uptake of FDG in the peripheral rim of the mass as a result of inflammation, should be recognized as a potential interpretive pitfall in mimicking a sarcoma.	15834566
Inflammation, Pneumonia	Altered Intercellular Communication	However, she did not fully recover, since aspiration pneumonia and mild generalized inflammation continued.	15835294
Chronic infectious disease, Inflammation	Altered Intercellular Communication	Patients are characterized by chronic infection, systemic inflammation, catabolism and impaired healing.	15835522
Communicable Diseases, Inflammation	Altered Intercellular Communication	The ostomies are closed several months later when infection and systemic inflammation are overcome and nutrition and healing capacity are restored.	15835522
Inflammation, Abdominal wall defect, Impaired	Altered Intercellular Communication	Effective techniques for management of abdominal defects, methods to establish enteral nutrition, minimize chronic inflammation and liver impairment as well as operative techniques and strategies are important.	15835522
HD Term Type, Inflammation	Altered Intercellular Communication	Evidence for persistent inflammation in HD was provided by elevated baseline levels of C-reactive protein, neopterin and lipid peroxidation products compared with controls.	15836620
Inflammation	Altered Intercellular Communication	Elevated serum levels of interleukin-6 (IL-6), an inflammatory cytokine and a member of the glycoprotein 130 (gp130) ligand family, are found in obese patients and might indicate low-grade systemic inflammation.	15837947
Inflammation, Heredity	Altered Intercellular Communication	Inflammation and heredity appear to be important factors in the development of AAA.	15838468
HIV	Altered Intercellular Communication	Numerous studies have already shown an association between STI-associated genital inflammation and human immunodeficiency virus (HIV) propagation.	15838790
Inflammation, Urinary Schistosomiasis	Altered Intercellular Communication	Therefore, the results of the present study suggest that male urogenital schistosomiasis may constitute a risk factor for HIV transmission, as a result of egg-induced inflammation in the semen-producing pelvic organs.	15838790
Communicable Diseases, Inflammation	Altered Intercellular Communication	The extraction of all deciduous teeth due to a poor prognosis and risk of systemic infection led to resolution of the oral inflammation.	15839398
Inflammation, Communicable Diseases, Prostate carcinoma, Benign prostatic hypertrophy, Malignant Neoplasms	Altered Intercellular Communication	To further analyse the relationship of c-reactive protein (CRP) levels to prostate cancer, by measuring CRP in men with prostate cancer and benign prostatic hypertrophy (BPH), as chronic inflammation has long been linked to cancers with an infectious cause and CRP is a nonspecific marker for inflammation, associated with prostate cancer incidence and progression.	15839913
Inflammation, Prostate carcinoma, Neoplasms	Altered Intercellular Communication	The strong association of CRP with PSA, independent of tumour stage, suggests that inflammation might be fundamental in prostate cancer, and that chronic inflammation may be a legitimate target for prostate cancer chemoprevention and treatment.	15839913
Inflammation	Altered Intercellular Communication	The further observation of an increased tissue kallikrein activity at the systemic and saliva levels may be interpreted as a systemic reflex of skin inflammation.	15840094
Inflammation, Fracture, Gastrointestinal mucositis	Altered Intercellular Communication	The most common complications for patients in the study group were soft tissue inflammation (mucositis) and cheek and lip biting (p < .05) whereas resin veneer fractures were the most common complications for the control group.	15841579
Inflammation, Gastrointestinal mucositis	Altered Intercellular Communication	Cleaning problems and associated soft tissue inflammation (mucositis) as well as tongue, lip, and cheek biting were significantly more often observed among the elderly patients (p < .05).	15841579
Airway structure	Altered Intercellular Communication	Compared with the ordinary dry powder type inhaled steroids, HFA-BDP can effectively diminish distal airway inflammation, suggesting the possibility that HFA-BDP can effectively reach to the distal small airway by forming super micro aerosol particles.	15841673
Inflammation	Altered Intercellular Communication	The median endoscopic score of inflammation was significantly decreased during intervention in the UC/IPAA patients.	15841713
Inflammation, Alveolar Bone Loss	Altered Intercellular Communication	Gingival inflammation (GBI %), pathological pocket depths, and alveolar bone loss diagnosed on radiographs were recorded.	15841815
Gingivitis, SLC25A20 gene	Altered Intercellular Communication	Regardless of CAC or resin composite, the restorations per se did not affect the GCF levels of IL-1 and IL-1ra, neither at healthy gingiva, nor at initiation of plaque-related gingival inflammation.	15842260
Neurodegenerative Disorders, Inflammation, Data types - Address, "Alzheimers Disease	Altered Intercellular Communication	Inflammation is profoundly involved in the development of Alzheimer's disease (AD) and other neurodegenerative diseases.	15843053
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Resistin is also shown to specifically accumulate in the inflamed joints of patients with rheumatoid arthritis and its levels correlate with other markers of inflammation.	15843582
Tuberculosis, Panniculitis, Lobular panniculitis	Altered Intercellular Communication	Inflammation of subcutaneous tissue (panniculitis) may occur in association with tuberculosis, but so far only three cases of non-tuberculous mycobacteria-related lobular panniculitis have been reported.	15844639
Acute Coronary Syndrome, Inflammation	Altered Intercellular Communication	In coronary syndromes, the importance of inflammation with platelet-leukocyte interaction has been demonstrated.	15845906
Inflammation, Myocardial	Altered Intercellular Communication	Markers of myocardial damage, inflammation, and homocysteine analyzed separately provide prognostic information.	15846264
Inflammation	Altered Intercellular Communication	One patient had scattered inflammation of the mucosa.	15846497
Celiac Disease, Inflammation	Altered Intercellular Communication	Celiac disease is an inflammation most frequently affecting the proximal small intestine, depending on the presence of gluten in the diet, whose pathogenesis seems to be immunological in nature.	15847385
Glomerulitis (disorder), Inflammation	Altered Intercellular Communication	The presence of glomerulitis may represent humoral factor-dependent inflammation.	15848511
Inflammation	Altered Intercellular Communication	It should be considered an important diagnostic criterion for CR in addition to double-contour formation and elastica disruptions with or without subendothelial inflammation (Banff '97).	15848511
Kidney Failure, Chronic, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Patients with end-stage renal disease (ESRD) suffer from high mortality rates of cardiovascular diseases, conditions closely linked to the magnitude of their chronic low-grade inflammation.	15849476
Kidney Failure, Chronic, Inflammation, Malnutrition	Altered Intercellular Communication	Baseline oxysterols and other markers of oxidative stress, inflammation and malnutrition in the vitamin e and intima media thickness progression in end-stage renal disease (VIPER) cohort.	15849477
Hepatitis C, Chronic, Hepatitis, Chronic, Hepatitis	Altered Intercellular Communication	Apoptotic cytokeratin 18 neoepitopes in serum of patients with chronic hepatitis C. In patients with chronic hepatitis C, alanine aminotransferase (ALT) levels do not accurately reflect the extent of liver inflammation.	15850472
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Association of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers.	15850494
Inflammation, Chronic Obstructive Airway Disease, Airway Obstruction	Altered Intercellular Communication	Inflammation in the airways and lung parenchyma underlies fixed airway obstruction in chronic obstructive pulmonary disease.	15850494
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The exact role of smoking as promoting factor of inflammation in chronic obstructive pulmonary disease is not clear, partly because studies often do not distinguish between current and ex-smokers.	15850494
Airway structure, Chronic Obstructive Airway Disease, Airway Obstruction	Altered Intercellular Communication	We investigated airway inflammation in sputum and bronchial biopsies of 34 smokers with chronic obstructive pulmonary disease (9 Global initiative for Chronic Obstructive Lung Disease stage 0, 9 stage I, 10 stage II and 6 stage III) and 26 asymptomatic smokers, and its relationship with past and present smoking habits and airway obstruction.	15850494
Primary Lesion, Primary hypogonadism	Altered Intercellular Communication	Basic hormonal blood tests showed a primary testicular lesion (hypergonadotropic hypogonadism).	15850541
Drusen, Inflammation	Altered Intercellular Communication	Quantitative RT-PCR measured increased expression of genes coding for drusen components, lipid transport, extracellular matrix components, and responses to inflammation in the rho(0) cells.	15851580
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation and Carotid Artery--Risk for Atherosclerosis Study (ICARAS).	15851593
Inflammation, Atherosclerosis	Altered Intercellular Communication	Compelling evidence suggests that inflammation is fundamentally involved in the pathogenesis of atherosclerosis; however, temporal correlation between inflammation and morphological features of atherosclerosis progression has not been demonstrated unequivocally.	15851593
Inflammation, Coronary Arteriosclerosis, Carotid Atherosclerosis	Altered Intercellular Communication	These findings supply evidence for a close temporal correlation between inflammation and morphological features of rapidly progressive carotid atherosclerosis, which suggests that elevation or increase of the inflammatory biomarkers hs-CRP and SAA identifies the presence of active atherosclerotic disease.	15851593
vascular inflammations	Altered Intercellular Communication	Histopathological findings in the acute stage of Kawasaki disease (KD) indicate widespread vascular inflammation that involves not only coronary arteries but also systemic arteries.	15851619
Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation and a decrease in subjective visual acuity were the most frequently reported findings (90% and 94%, respectively).	15851947
Inflammation, Hemorrhage, Fibrosis Assessment	Altered Intercellular Communication	We believe that inflammation surrounding the coiled aberrant artery, presumably caused by injury during the corrective surgery and resulting in hemorrhage, led to fibrosis around the vessel.	15852258
Airway structure, Asthma	Altered Intercellular Communication	Furthermore, mbl levels of asthmatic children positively correlated with peripheral blood eosinophils (r = 0.377, p < 0.001), which is a systemic component of airway inflammation in asthma.	15853952
Airway structure, Asthma	Altered Intercellular Communication	Our findings indicate that mbl may be implicated in the pathogenesis of asthma by contributing to airway inflammation or by increasing the risk of developing asthma.	15853952
Airway structure	Altered Intercellular Communication	Measurement of exhaled nitric oxide (eNO) offers a non-invasive means for assessment of airway inflammation.	15853955
Inflammation, Mediastinitis, Atherosclerosis	Altered Intercellular Communication	As inflammation began to be recognized as a major contributor to the pathogenesis of atherosclerosis, we evaluated the patients that developed mediastinitis, a long-standing inflammatory process, after coronary artery bypass grafting.	15854079
Inflammatory Bowel Diseases, Inflammation, Cachexia	Altered Intercellular Communication	Increasing evidence shows that inflammation plays a major role in the aetiology of catabolism and wasting observed in inflammatory bowel disease via growth hormone resistance.	15854167
Inflammatory Bowel Diseases, Inflammation, Cachexia	Altered Intercellular Communication	Increasing evidence shows that inflammation plays a major role in the aetiology of catabolism and wasting observed in inflammatory bowel disease via growth hormone resistance.	15854167
Kidney Failure, Chronic, Inflammation, Malnutrition, Cardiovascular Diseases	Altered Intercellular Communication	As a result, on-line HDF might aggravate chronic inflammation, which correlates with malnutrition, cardiovascular disease, and mortality among ESRD patients.	15854217
Hernia of cerebellar tonsil into foramen magnum, Tonsillitis	Altered Intercellular Communication	Spontaneous resolution of acquired tonsillar herniation caused by isolated cerebellar tonsil inflammation: case report.	15854268
Arnold-Chiari Malformation, Type I, Infectious Mononucleosis, Tonsillitis	Altered Intercellular Communication	An unusual case is reported in which regression of an acquired Chiari I malformation caused by isolated cerebellar tonsil inflammation in a patient with infectious mononucleosis was observed after conservative treatment.	15854268
Restless Legs Syndrome	Altered Intercellular Communication	The predictive value of serum ferritin for iron deficiency in RLS depends on the cutoff employed, on the pre-test likelihood of iron deficiency and on coexisting inflammatory conditions.	15854860
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	This suggests that a lower inflammation state, as attested by low CRP levels, could play a role in the protective profile of the MHO individual, and this may be associated metabolically to a lower risk for cardiovascular disease.	15855252
Gingivitis, Attachment (action), Periodontitis	Altered Intercellular Communication	In this study of subjects with minimal attachment loss, gingival inflammation was associated with early periodontitis.	15857098
Neoplasms, Hobnail Hemangioma	Altered Intercellular Communication	We report the third case in the literature of a hobnail haemangioma with cyclic changes throughout the menstrual cycle in a 36-year-old woman, suggesting a hormonal basis for the variations in the tumour.	15857469
Inflammation, Cutaneous	Altered Intercellular Communication	Such a high concentration of salt in the sweat during the depletive crises directly causes inflammation and damage in the eccrine structures, with cutaneous lesions similar to those appearing in miliaria rubra.	15857472
Cerebrovascular Disorders, Inflammation, Neoplasms, Congenital Abnormality	Altered Intercellular Communication	The etiologies were 4 tumors, 3 intracranial vascular disorders, 2 Wernicke encephalopathies, 1 congenital anomaly, and 1 inflammation.	15859150
Inflammation	Altered Intercellular Communication	Therefore, any disease accompanied by inflammation can be threatening to the muscle function in geriatric patients.	15860475
Inflammation, primary disorders	Altered Intercellular Communication	Geriatric hospitalized patients presenting with inflammation show significantly worse muscle functions, which do not improve during hospitalization despite adequate treatment of the primary disease.	15860475
Inflammation, Asthma	Altered Intercellular Communication	These data provide evidence that, in asthmatic children, the epithelium is stressed or injured without significant eosinophilic inflammation.	15860714
Inflammation, Mirizzi Syndrome, Specimen Type - Fistula	Altered Intercellular Communication	We suggest that the natural history of Mirizzi syndrome does not end with a cholecystobiliary fistula but that the continuous inflammation in the triangle of Calot may result in a complex fistula involving not only the biliary tract but also the adjacent viscera.	15862264
Inflammation, Electrocardiogram: myocardial infarction (finding), Atherosclerosis	Altered Intercellular Communication	Variation in the gene encoding toll-like receptor 4 (TLR4), a transmembrane receptor that mediates inflammatory responses to bacterial endotoxin, has been associated with susceptibility to atherosclerosis and its complications, such as myocardial infarction (MI), the pathogenesis of which involves inflammation.	15864121
Colon Carcinoma, Neoplasm Metastasis, Hypercalcemia, CTCAE	Altered Intercellular Communication	Here we present the first case of adenosquamous carcinoma of the sigmoid colon in a patient who was found to have hypercalcemia associated with parathyroid hormone-related protein (PTHrP), with no radiological evidence of metastasis to other organs.	15864702
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Cyclooxygenase-2 (COX-2) is an inducible enzyme important in inflammation and which is overexpressed in a variety of cancers.	15864753
Gastroesophageal reflux disease, Inflammation, Esophagitis	Altered Intercellular Communication	All patients were divided into 2 groups: first consisted of patients (51) with no signs of esophagitis and the second one (41) included individuals with gastro-oesophageal reflux complicated with inflammation.	15865235
Inflammation, Phlebitis	Altered Intercellular Communication	These patients were divided into two groups: 60 patients with phlebitis and 36 without local signs of inflammation.	15866010
Acute and chronic inflammation	Altered Intercellular Communication	The chronic active inflammation is dominated by neutrophils, macrophages, lymphocytes and plasma cells.	15866221
Nonulcer dyspepsia, Gastritis	Altered Intercellular Communication	The aim of this study was to investigate the gastric inflammation in patients with functional dyspepsia.	15866221
Gastritis	Altered Intercellular Communication	Only CD4 and CD19 were significantly increased in patients with increased gastric inflammation and increased density of H. pylori.	15866221
Gastritis	Altered Intercellular Communication	However, several of the examined markers (IFN-gamma, IL-8, IL-10 and CD14) showed a non-significant trend to be increased in patients with extensive gastric inflammation and high density of H. pylori.	15866221
Inflammation	Altered Intercellular Communication	Significant increases in the index from none to moderate antral inflammation as well as the density of H. pylori were found (p<0.001).	15866221
Nonulcer dyspepsia, Gastritis	Altered Intercellular Communication	By using an index of inflammatory markers trends can be summarized and thereby significant which may be of importance when gastric inflammation is investigated in children and patients with functional dyspepsia.	15866221
Inflammation, Periprosthetic Fractures	Altered Intercellular Communication	Periprosthetic tissue formation and local inflammation that are associated with wear debris contribute to the pathogenesis of aseptic loosening of a prosthesis.	15866974
cannabidiol, Berylliosis, Disease, Granulomatous inflammation	Altered Intercellular Communication	A subset of beryllium-sensitized (BeS) subjects progress to chronic beryllium disease (CBD), a disorder characterized by a CD4+ T-cell alveolitis and granulomatous inflammation.	15867863
Inflammation	Altered Intercellular Communication	Higher numbers of beryllium-specific cells in blood were also associated with the extent of alveolar inflammation, as measured by both bronchoalveolar lavage white blood cell and lymphocyte counts.	15867863
Inflammation, Atherosclerosis, Diabetes Mellitus	Altered Intercellular Communication	Inflammation plays a pathogenic role in the development of accelerated atherosclerosis in diabetes.	15868137
Inflammation, Colitis	Altered Intercellular Communication	Serologic responses in indeterminate colitis patients before ileal pouch-anal anastomosis may determine those at risk for continuous pouch inflammation.	15868228
Inflammation, Pouchitis, Crohn Disease	Altered Intercellular Communication	Although acute pouchitis after ileal pouch-anal anastomosis is common and easily treated, continuous pouch inflammation seen clinically as chronic, antibiotic-dependent pouchitis, and/or Crohn's disease remains a difficult management problem.	15868228
Inflammation, Ulcerative Colitis, Colitis	Altered Intercellular Communication	Compared with ulcerative colitis, indeterminate colitis patients undergoing ileal pouch-anal anastomosis have a higher incidence of continuous pouch inflammation, which may represent persistent immune reactivity to microbial antigens.	15868228
Inflammation, Crohn Disease	Altered Intercellular Communication	Of 16 patients (61 percent) who developed pouch inflammation, 4 (25 percent) had acute pouchitis and 12 (75 percent) had continuous pouch inflammation (9 had chronic pouchitis, 3 had Crohn's disease).	15868228
Inflammation	Altered Intercellular Communication	Serologic expression of any marker alone did not predict the development of continuous pouch inflammation.	15868228
Inflammation	Altered Intercellular Communication	However, continuous pouch inflammation developed in 10 of 16 patients (63 percent) who had a positive antibody reactivity profile compared with only 2 of 12 patients (17 percent) who had a negative antibody reactivity profile (P = 0.015).	15868228
Inflammation, Colitis	Altered Intercellular Communication	Indeterminate colitis patients who have a positive antibody reactivity profile before ileal pouch-anal anastomosis have a significantly higher incidence of continuous pouch inflammation after surgery than those with a negative profile.	15868228
Inflammation	Altered Intercellular Communication	Conversion to open cholecystectomy was needed in 94 patients (5.2%),of which 44 (2.8%) had no inflammation and 50 (18.4%) had acute inflammation of the gallbladder.	15868267
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Male gender, age older than 60 years, previous upper abdominal surgery, diabetes, and severity of inflammation were all significantly correlated with an increased conversion rate to laparotomy.	15868267
Inflammation, Fever, CTCAE, Acute Cholecystitis	Altered Intercellular Communication	Also, the conversion from laparoscopic to open cholecystectomy in acute cholecystitis patients was associated with greater white blood cell count, fever, elevated total bilirubin, aspartate transaminase, and alanine transaminase levels, and the various types of inflammation.	15868267
Stomatitis, Helicobacter pylori, Stomach Carcinoma	Altered Intercellular Communication	Gastric carcinoma occurs in response to chronic inflammation of gastric mucosa infected with Helicobacter pylori.	15868900
Inflammation	Altered Intercellular Communication	Endothelial cell membrane-bound thrombomodulin (TM) plays a critical role as a cofactor in the protein C pathway, important in regulating coagulation as well as inflammation.	15869594
Inflammation	Altered Intercellular Communication	An increased matrix metalloproteinase-9 expression in the extracellular matrix was observed in relation to the severity of inflammation.	15869913
Unknown (origin) (qualifier value), Subfertility, Endometriosis	Altered Intercellular Communication	The sensitivity for subfertility attributed to tubal, male, hormonal, cervical, uterine, and idiopathic factors and for endometriosis was 84%, 78%, 65%, 40%, 46%, 59%, and 83%, respectively.	15870163
Arterial Stiffness, Inflammation, Malnutrition	Altered Intercellular Communication	Calcaneal OSI, a surrogate marker for estimated BMD, has a strong ability to predict the severity of arterial stiffness independent of classical risk factors and markers of inflammation and malnutrition.	15870495
Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	A prospective longitudinal study of performance status, an inflammation-based score (GPS) and survival in patients with inoperable non-small-cell lung cancer.	15870712
Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	The value of an inflammation-based prognostic score (Glasgow Prognostic score, GPS) was compared with performance status (ECOG-ps) in a longitudinal study of patients (n=101) with inoperable non-small-cell lung cancer (NSCLC).	15870712
Inflammation, Decreased renal function	Altered Intercellular Communication	Blood samples revealed decreased renal function and increased inflammation parameters.	15870994
Inflammation	Altered Intercellular Communication	We found the correlation between IFN-g concentration in the cerebrospinal fluid of patients at the early stage of TBE and inflammation activity.	15871055
Cessation of life, Shock	Altered Intercellular Communication	Inflammation markers and their serial changes predict death and shock in patients with STEMI undergoing primary angioplasty.	15872036
Inflammation, Peripheral Arterial Diseases	Altered Intercellular Communication	In patients with peripheral artery disease, neutrophil counts in the upper tertile (>5.8 G/L) indicate a substantially increased risk for major adverse cardiovascular events, adding to the prognostic information of traditional atherothrombotic risk factors and other parameters of inflammation.	15874924
Hyperkeratosis, Corneal Opacity, Cataract, ICHTHYOSIS PREMATURITY SYNDROME, Endocrine System Diseases, Thyroid Hypoplasia, hormone deficiency	Altered Intercellular Communication	Hypoplastic thyroid, growth hormone deficiency, corneal opacities, cataract and hyperkeratotic skin disease: a possible new ichthyosis syndrome associated with endocrinopathies.	15875205
Inflammation, Traumatic injury, Endophthalmitis	Altered Intercellular Communication	Many cases of bilateral blindncss associated with injury and inflammation were diagnosed as sympathetic ophthalmia.	15875482
Inflammation, Fibrosis Assessment, Endometriosis	Altered Intercellular Communication	Focal endometriosis was identified in 28 (40%) of the biopsies, nine (12.9%) displayed other manifestations of 'mullerianosis', 11 (15.7%) showed focal chronic inflammation or fibrosis only, and 22 (31.4%) displayed no specific pathological changes.	15875729
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Inflammation plays an important role in the pathophysiology of stroke.	15876336
Inflammation, Steatohepatitis, Fibrosis Assessment, Complete atrioventricular block, Carcinogenic Chlorinated Hydrocarbon	Altered Intercellular Communication	The aims of this study were to investigate predictors of hepatic steatosis, and their impact on inflammation and fibrosis in CHB and CHC.	15876468
Inflammation	Altered Intercellular Communication	Monocytes from dialysis patients exhibit characteristics of senescent cells: does it really mean inflammation?	15876845
Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain and inflammation in 41 patients following the placement of 131 dental implants.	15876971
Pain Distress Question, Swelling, Inflammation	Altered Intercellular Communication	Swelling was moderate in most patients who reported pain -- peak intensity of inflammation being recorded after 48 hours in 48.8% of cases.	15876971
Pain Distress Question, Inflammation	Altered Intercellular Communication	Following implant placement, pain tends to be mild, with moderate inflammation.	15876971
Atherosclerosis of renal artery, Inflammation	Altered Intercellular Communication	Circulating markers of inflammation are related to carotid artery atherosclerosis.	15876998
Inflammation, Thrombosis	Altered Intercellular Communication	The role of inflammation in atherothrombotic disorders is becoming increasingly recognized.	15876998
Atherosclerosis of renal artery, Inflammation	Altered Intercellular Communication	Several biomarkers of inflammation are related to ultrasonographic measures of carotid artery atherosclerosis in patients with moderate to high prevalence of CAD.	15876998
Inflammation, Dental Plaque	Altered Intercellular Communication	Pretreatment gingival recession, width of keratinized gingiva, gingival biotype, gingival inflammation, and visible plaque accumulation were recorded, as was posttreatment gingival recession.	15877035
Inflammation, Hyperplasia, Hypertrophy	Altered Intercellular Communication	The most frequently observed abnormalities were acute and chronic inflammation of the mucosa and submucosa, focal or generalized thinning of muscle layers, especially of the outer muscle coat, disorganized muscle layers, a decreased number of mature ganglion cells, and neuronal hyperplasia and hypertrophy in nerve plexuses.	15877258
Cytomegalovirus Infections, Inflammation	Altered Intercellular Communication	Chronic cytomegalovirus infection and inflammation are associated with prevalent frailty in community-dwelling older women.	15877548
Communicable Diseases, Inflammation	Altered Intercellular Communication	To evaluate the association between asymptomatic chronic cytomegalovirus (CMV) infection and the frailty syndrome and to assess whether inflammation modifies this association.	15877548
Cytomegalovirus Infections, Inflammation	Altered Intercellular Communication	Chronic CMV infection is associated with prevalent frailty, a state with increased morbidity and mortality in older adults; inflammation enhances this effect.	15877548
Inflammation, Cytomegalovirus	Altered Intercellular Communication	Further prospective studies are needed to establish a causal relationship between CMV, inflammation, and frailty.	15877548
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Accordingly, a therapy for treating UC was designed, with the aim of modifying the mucosal microbiota to increase bifidobacterial colonisation and reduce inflammation.	15877898
Inflammation	Altered Intercellular Communication	Results demonstrated that short-term synbiotic treatment resulted in increased bifidobacterial colonisation of the rectal mucosa and induced significant reductions in the expression of molecules that control inflammation in active UC.	15877898
Communicable Diseases, Inflammation	Altered Intercellular Communication	Wound inflammation of only very mild degree occurred in 15% in the fascia lata group, whereas 33% in the polyethylene group developed serious sling infection; in three patients explantation of the sling was necessary.	15877939
Inflammation	Altered Intercellular Communication	Inflammation has been associated with increased cardiovascular risk, and endothelial cell (EC) apoptosis has been implicated in atherogenesis.	15878008
Inflammation	Altered Intercellular Communication	EC apoptosis is associated with IL-6 levels in men and might be partially responsible for the increased cardiovascular risk associated with subclinical inflammation.	15878008
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation was assessed at each visit with standardized grading scales.	15878055
Conjunctivitis	Altered Intercellular Communication	During the follow-up of 14.16+/-5.2 months, all eyes showed a marked reduction of conjunctival inflammation, a deep fornix, and a continuous tear meniscus.	15878073
Conjunctivitis	Altered Intercellular Communication	Intraoperative application of mitomycin C is an effective means to reduce chronic and deep-seated conjunctival inflammation, and helps amniotic membrane restore a deep fornix after symblepharon lysis, even in eyes that had a failed MMG.	15878073
Inflammation	Altered Intercellular Communication	Patients with acute SJS/TENS are characterized by severe inflammation and ulceration of the tarsal conjunctiva and lid margins.	15878074
Inflammation	Altered Intercellular Communication	Attempts to suppress inflammation and scarring by amniotic membrane transplantation at the acute stage and to prevent microtrauma at the chronic stage are vital to avoid sight-threatening complications.	15878074
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Effect of inhalation of thermal water on airway inflammation in chronic obstructive pulmonary disease.	15878492
Airway structure	Altered Intercellular Communication	However, the short-term improvement in some components health-related quality of life was not related with changes in lung function or with the degree of airway inflammation.	15878492
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	IFNbeta may have immunomodulatory effects in rheumatoid arthritis (RA) and its increased production in RA synovium may be a reactive attempt to inhibit inflammation.	15878901
Refractory anemias, Inflammation	Altered Intercellular Communication	The increased expression of IFNbeta in RA synovium suggests activation of an immunomodulatory mechanism that could inhibit synovial inflammation.	15878901
Degenerative polyarthritis, Inflammation, Hypertrophy, Pain Distress Question	Altered Intercellular Communication	Synovial inflammation (as defined by hypertrophy and effusion) is common in osteoarthritis (OA) and may be important in both pain and structural progression.	15878902
Inflammation	Altered Intercellular Communication	To determine if decision rules can be devised from clinical findings and ultrasonography (US) to allow recognition of synovial inflammation in patients with painful knee OA.	15878902
Inflammation	Altered Intercellular Communication	Although it is possible to determine clinical and radiological predictors of OA inflammation in populations, CART analysis could not be used to devise useful clinical decision rules for an individual subject.	15878902
Inflammation	Altered Intercellular Communication	Thus sensitive imaging techniques such as US remain the most useful tool for demonstrating synovial inflammation of the knee at the individual level.	15878902
Inflammation, Hydrarthrosis, Synovitis, Degenerative polyarthritis, Osteoarthritis, Knee, effusion	Altered Intercellular Communication	To assess the prevalence of inflammation in subjects with chronic painful knee osteoarthritis (OA), as determined by the presence of synovitis or joint effusion at ultrasonography (US); and to evaluate the correlation between synovitis, effusion, and clinical parameters.	15878903
Synovitis, Inflammation, Hydrarthrosis, effusion	Altered Intercellular Communication	At US 16 (2.7%) had synovitis alone, 85 (14.2%) had both synovitis and effusion, 177 (29.5%) had joint effusion alone, and 322 (53.7%) had no inflammation according to the definitions employed.	15878903
Inflammation, Hydrarthrosis, Knee pain, Synovitis, CONE, RADIOGRAPHIC	Altered Intercellular Communication	Multivariate analysis showed that inflammation seen by US correlated statistically with advanced radiographic disease (Kellgren-Lawrence grade >or=3; odds ratio (OR)=2.20 and 1.91 for synovitis and joint effusion, respectively), and with clinical signs and symptoms suggestive of an inflammatory "flare", such as joint effusion on clinical examination (OR=1.97 and 2.70 for synovitis and joint effusion, respectively) or sudden aggravation of knee pain (OR=1.77 for joint effusion).	15878903
Degenerative polyarthritis, Inflammation, Synovitis, effusion	Altered Intercellular Communication	US can detect synovial inflammation and effusion in painful knee OA, which correlate significantly with knee synovitis, effusion, and clinical parameters suggestive of an inflammatory "flare".	15878903
Inflammation, Carcinogenesis	Altered Intercellular Communication	Chronic inflammation has been linked to carcinogenesis in various tissue sites.	15878911
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	However, it is not clear whether the primary stimulus for the high COX-2 levels is related to inflammation or malignancy.	15878911
nervous system disorder, Inflammation, Cessation of life, Cerebrovascular accident	Altered Intercellular Communication	It has been suggested that 15-dPGJ2 could be beneficial in neurological disorders in which inflammation contributes to cell death such as stroke.	15879329
Granulomatous inflammation	Altered Intercellular Communication	All 30 patients (100%) had histopathological evidence of granulomatous inflammation with fungal spherules.	15879796
Inflammation, Vasculitis, CTCAE, Necrosis	Altered Intercellular Communication	Systemic vasculitis are a group of heterogeneous diseases characterized by inflammation and necrosis of blood vessel walls.	15880180
Inflammation	Altered Intercellular Communication	The 50 most differentially expressed genes in the primary SS group compared with the control group were all up-regulated, and a clear pattern of genes involved in chronic inflammation was found.	15880807
Inflammation, Chronic inflammation, Eosinophilic inflammation, Sinusitis, Asthma	Altered Intercellular Communication	These findings suggest that patients with both sinusitis and asthma present the histopathologic characteristic of a marked chronic inflammatory reaction, and that eosinophil infiltration may play a significant role in this marked inflammation of the sinus mucosa.	15880948
Superficial ulcer, Inflammation	Altered Intercellular Communication	Histologically, the lesions corresponded to dilated vessels in the mucosa and submucosa in the absence of erosions or inflammation.	15881011
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	This area represents myocardial fibrosis due to recurrent inflammation.	15881537
Inflammation, Hemorrhage, Destruction of tissue	Altered Intercellular Communication	Periodontal therapy resulted in a significant reduction of local inflammation and tissue destruction as reflected in reduced pocket depths and reduced bleeding indices.	15882224
Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	Scaling and root planing was effective in reducing levels of plaque, inflammation, and bleeding upon probing.	15882229
Down Syndrome, Inflammation	Altered Intercellular Communication	Clinical indices of periodontal inflammation and treatment needs were statistically significant higher among Down syndrome patients compared with the other two groups (ANOVA, p=0.000).	15882231
Kidney Failure, Chronic, Inflammation, Endothelial dysfunction, Cardiomyopathies	Altered Intercellular Communication	Prognostic value of combined use of biomarkers of inflammation, endothelial dysfunction, and myocardiopathy in patients with ESRD.	15882276
Inflammation, AHSG protein, human, Vascular calcification	Altered Intercellular Communication	Fetuin-A, a circulating calcium-regulatory glycoprotein that inhibits vascular calcification, is associated with inflammation and outcome in dialysis patients.	15882283
Albumins, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus	Altered Intercellular Communication	Both all-cause (P < 0.001) and cardiovascular (P < 0.001) mortality were associated with low fetuin-A levels independently of age, smoking, diabetes, S-albumin, CVD, and inflammation (CRP > or =10 mg/L).	15882283
Albumins, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	In a logistic regression model (N= 101), fetuin-A was significantly (P < 0.05) associated with the presence of carotid plaques independently of age, CVD, diabetes, S-albumin, gender, and inflammation.	15882283
Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	The present study shows that a low fetuin-A level is associated with malnutrition, inflammation, and atherosclerosis (carotid plaques), as well as with increased cardiovascular and all-cause mortality.	15882283
Inflammation, polychondritis	Altered Intercellular Communication	Relapsing polychondritis is a rare disease of unknown etiology causing systematic inflammation of the whole cartilaginous tissues.	15882830
Orchitis	Altered Intercellular Communication	Oral predonine administration was initiated, and the auricular inflammation was improved within 10 days.	15882830
Intraocular inflammation, Exudative retinopathy, Retinal vascular occlusion	Altered Intercellular Communication	Patients with a history of radiation exposure, intraocular inflammation, retinal vascular occlusion, or Coats' response were excluded.	15882905
Inflammation, Squamous metaplasia	Altered Intercellular Communication	Squamous metaplasia and inflammation was present in 3 cases each.	15883073
Inflammation, deficiency aspects	Altered Intercellular Communication	Reactive inflammation of the normal pituitary gland may have a role in the pathogenesis of hormonal deficiency, in addition to compression.	15883073
Hormone abnormality, Visual Impairment, Headache	Altered Intercellular Communication	In the surgical group, headache was present in 4 patients, hormonal abnormality in 4, visual deficits in 3, and otolaryngological symptoms in 2.	15883073
Inflammation, deficiency aspects	Altered Intercellular Communication	Reactive inflammation of the normal pituitary gland may have a role in the pathogenesis of hormonal deficiency, in addition to compression.	15883073
Pancreatitis	Altered Intercellular Communication	There is only one report which implies the involvement of both drugs in pancreatic inflammation.	15883478
Gastritis, Duodenal Ulcer	Altered Intercellular Communication	Association of the myeloperoxidase -468G-->A polymorphism with gastric inflammation and duodenal ulcer risk.	15884126
APP gene, Inflammation	Altered Intercellular Communication	Despite patient differences, the composition of the AAA inflammatory infiltrate was remarkably consistent, and when re-stimulated ex-vivo T cells produced a stereotypical cytokine response, consistent with the hypothesis that AAA T cells can promote tissue inflammation by secretion of proinflammatory cytokines, and in addition provide signals for B-cell help.	15885133
Intraocular inflammation	Altered Intercellular Communication	The primary safety measures were changes from baseline in VA, intraocular pressure (IOP), intraocular inflammation, and production of antiranibizumab antibody.	15885778
Intraocular inflammation, Hemorrhage, Toxic effect	Altered Intercellular Communication	Dose-limiting toxicity was defined by intraocular inflammation, elevated IOP, reduced VA, or hemorrhage within 90 days after injection.	15885778
Intraocular inflammation	Altered Intercellular Communication	At the higher dose of 1000 microg, significant intraocular inflammation was noted.	15885778
Inflammatory abnormality of the eye	Altered Intercellular Communication	Aqueous or vitreous ocular inflammation occurred in 12 subjects, with complete resolution within 42 days.	15885778
Psoriatic Juvenile Idiopathic Arthritis, melanoma, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	Proteasomes are strongly expressed in cutaneous MM; high levels of circulating proteasomes are detected in patients with metastatic MM with a high melanoma burden, and at a lesser extent in psoriatic patients, which suggests proteasomes represent a marker more of nonspecific inflammation than of early cancer.	15888151
Gastrointestinal inflammation	Altered Intercellular Communication	indicator of intestinal inflammation and/or defect in mucosal defence, is a strong mortality predicting factor.	15888338
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by chronic airway inflammation that is greater in patients with advanced disease.	15888697
Dry cough	Altered Intercellular Communication	Noneosinophilic CD4 lymphocytic airway inflammation in menopausal women with chronic dry cough.	15888851
Airway structure, Dry cough	Altered Intercellular Communication	HLA-DR-activated CD4+ lymphocytic airway inflammation with a low number of eosinophils was identified in a group of nonsmoking, nonatopic otherwise healthy women patients with dry cough of life-long character.	15888851
Inflammation, Ischemic stroke	Altered Intercellular Communication	Though there are several studies showing the importance of APPs as inflammation markers in acute ischemic stroke (AIS), the time course of these proteins during acute phase of AIS is not well known.	15888964
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	These findings support the importance of inflammation processes after stroke.	15888964
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	The upregulation of serum OPG might be the result of the inflammation; in contrast, an upregulation of RANKL could not be found in the serum of patients with RA and OA.	15889303
Inflammation, septic	Altered Intercellular Communication	Although serious systemic inflammation associated with i. v.-injection in drug addicts is rare, one has to be aware of severe complications with septic emboli.	15889322
Cerebrovascular, Inflammation	Altered Intercellular Communication	Increasing evidence suggests that inflammation plays an important role in the development of both cardiovascular and cerebrovascular events.	15889566
Airway structure	Altered Intercellular Communication	Exposure to environmental tobacco smoke (ETS), which contains potent respiratory irritants, may lead to chronic airway inflammation and obstruction.	15890079
Inflammation	Altered Intercellular Communication	These results suggest that inflammation may have a role in the pathogenesis of AF resistant to antiarrhythmic drugs.	15890767
Inflammation, Actual blood loss, Anemia	Altered Intercellular Communication	Exploration of the mechanisms of S. japonicum-associated anemia suggests that processes other than extracorporeal blood loss, such as anemia or inflammation, may be involved.	15891125
Inflammation, Lymphadenopathy	Altered Intercellular Communication	FDS detection was more common in older children (P = 0.003) and in those with a history of inguinal lymph node inflammation (P = 0.002) or crural lymphadenopathy on physical exam (P = 0.01).	15891143
Cerebritis, Inflammation	Altered Intercellular Communication	Two patients had a rapidly progressive, fatal course, with cerebritis and acute inflammation; fungal organisms were largely restricted to vessels.	15891169
Inflammation, Necrosis	Altered Intercellular Communication	Six patients with subacute neurologic presentations had acute or chronic inflammation, capsule formation, focal necrosis, and fungal organisms disseminated throughout the lesion.	15891169
Suppuration, Inflammation, Cerebral abscess, Necrosis	Altered Intercellular Communication	Fungal cerebral abscesses may have central restricted diffusion similar to that of bacterial abscesses but with histologic features of acute or chronic inflammation and necrosis rather than suppuration.	15891169
Inflammation, Atherosclerosis	Altered Intercellular Communication	There is increasing evidence that inflammation plays an important role in atherosclerosis.	15891266
myocardial injury, Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	These measurements were correlated with markers of systemic inflammation (hs-CRP) in all subjects and myocardial injury (troponin T) in patients with ACS.	15892761
Invasive Lesion, Inflammation	Altered Intercellular Communication	We hypothesized that color analyses of these three wave lengths would improve our ability to differentiate between inflammation and preinvasive lesions.	15892998
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Diffuse and active inflammation occurs in both vulnerable and stable plaques of the entire coronary tree: a histopathologic study of patients dying of acute myocardial infarction.	15893171
Acute myocardial infarction, Arteritis	Altered Intercellular Communication	This study was undertaken to define and compare geographic coronary artery inflammation in patients who were dying of acute myocardial infarction (AMI), chronic stable angina (SA), and noncardiac causes (CTRL).	15893171
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Biochemical markers and flow cytometry provide indirect evidence of diffuse coronary inflammation in patients dying of acute coronary syndromes.	15893171
Inflammation	Altered Intercellular Communication	In AMI patients, active inflammation was not only evident within the culprit lesion and vulnerable plaques but also involved stable plaques.	15893171
Inflammation	Altered Intercellular Communication	These showed a three- to four-fold higher inflammation than vulnerable and stable plaques from the SA and CTRL groups, respectively.	15893171
Rupture, Inflammation	Altered Intercellular Communication	Multiple plaque rupture is associated with systemic inflammation, and patients with multiple plaque rupture can be expected to show a poor prognosis.	15893172
Inflammation, Arthritis, Pannus	Altered Intercellular Communication	Inflamed synovium produces and releases lipids, most probably arachidonic acid metabolites that inhibit cell proliferation thus limiting inflammation and pannus formation in arthritis.	15893949
Cholecystitis, Inflammation, Biliary calculi, Cholangitis	Altered Intercellular Communication	The association of gallbladder and bile duct cancers with gallstones, cholecystitis, and cholangitis suggest that chronic inflammation contributes to the carcinogenic process.	15894693
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Patients affected by end-stage renal disease (ESRD) demonstrate a very high cardiovascular risk mediated by traditional cardiovascular risk factors as well as abnormal mineral metabolism and a state of chronic inflammation.	15894962
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Because circulating mononuclear cells (MNCs) are involved in inflammation mechanisms, these cells were chosen as the experimental model to evaluate PARP-1 levels and activity in patients with type 2 diabetes.	15895395
Communicable Diseases, Abnormal inflammatory response, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus	Altered Intercellular Communication	The different PARP-1 behavior in MNCs from patients with type 2 diabetes could therefore be responsible for the abnormal inflammation and infection responses in diabetes.	15895395
Inflammation, Dementia, Vascular, "Alzheimers Disease", Data types - Address, Cerebrovascular accident	Altered Intercellular Communication	Alzheimer disease (AD), vascular dementia, and stroke are all associated with inflammation though their respective initiating factors differ.	15895461
Cessation of life, Inflammation, Iliac Aneurysm	Altered Intercellular Communication	The objective of this study was to investigate the role of inflammation, programmed cell death, its molecular modulators, and proteolysis in the pathogenesis of iliac artery aneurysms (IAAs).	15895673
Neoplasms	Altered Intercellular Communication	This process can be difficult and unreliable, as tumor lesions may be visually indistinguishable from benign inflammatory conditions and the surrounding mucosa.	15896077
Endothelial dysfunction, Arteritis	Altered Intercellular Communication	Unstable angina (UA) is characterized by a state of coronary artery vascular inflammation and endothelial dysfunction.	15896616
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Statins mitigate inflammation and endothelial dysfunction and decrease mortality associated with percutaneous interventions for UA.	15896616
Inflammation, Myocardial Infarction, Myocardial dysfunction	Altered Intercellular Communication	Additionally to CS blood arterial blood was analyzed 4, 12, and 24 h postoperatively to determine myocardial necrosis (CK-MB, cardiac troponin I), myocardial dysfunction (NT-proBNP) and inflammation (C-reactive protein).	15896617
Communicable Diseases, Inflammation	Altered Intercellular Communication	Procalcitonin and C-reactive protein concentrations, clinical symptoms of infection and systemic inflammation were recorded preoperatively and 5 days postoperatively in 157 patients undergoing the following procedures: 52 wedge resections, 28 pneumonectomies and 77 lobectomies (or bilobectomies).	15896620
Sepsis	Altered Intercellular Communication	Despite the advances in therapeutic approaches in the management of inflammatory conditions, the incidence of sepsis is on increase in the intensive care units (ICU).	15897800
Rheumatoid Arthritis, Chronic small plaque psoriasis, Arthritis, Psoriatic	Altered Intercellular Communication	Inhibition of TNF-alpha has been shown to provide benefit in such inflammatory conditions as rheumatoid arthritis, psoriatic arthritis, and, most recently, plaque psoriasis.	15898294
Inflammation, Perforation of gallbladder	Altered Intercellular Communication	The effect of the degree of histologic inflammation on gallbladder perforation during laparoscopic cholecystectomy.	15898902
Inflammation, Tissue Adhesions, Perforation of gallbladder	Altered Intercellular Communication	Patients with and without gallbladder perforation were compared in terms of gender, age, anatomic difficulty, experience of the surgeon, omental and other organ adhesions to the gallbladder, and the findings of inflammation on the resected gallbladder.	15898902
Saint Lucia, Inflammation, Perforation of gallbladder	Altered Intercellular Communication	Acute inflammation, degree of anatomic difficulty, the experience of the surgeon, and omental or other organ adhesions were associated with gallbladder perforation during LC.	15898902
Inflammation	Altered Intercellular Communication	Interleukin-18 (IL-18) is reported as an important regulatory cytokine in non-oral inflammation.	15898940
Inflammation	Altered Intercellular Communication	Periodontal inflammation may not successfully resolve because of accumulation of IL-6 and IL-18, and decreased concentrations of IL-12, within diseased gingiva.	15898940
Inflammation, Suppurative Periapical Periodontitis	Altered Intercellular Communication	Upon clinical examination, severe inflammation of all gingival tissues was apparent, and a periapical abscess with mobility was noted on the left mandibular second molar.	15898946
Bacterial Infections	Altered Intercellular Communication	Inflammation of her oral tissues and recurrent bacterial infections were apparent.	15898946
Airway structure, Respiratory Hypersensitivity, Bronchitis	Altered Intercellular Communication	We have performed a longitudinal study of symptoms, eosinophilic airway inflammation, spirometry and airway hyper-responsiveness in all patients diagnosed with eosinophilic bronchitis over 7 years.	15898981
Airway structure	Altered Intercellular Communication	The remaining patients had ongoing eosinophilic airway inflammation and/or continuing symptoms.	15898981
Airway structure	Altered Intercellular Communication	The most important factors associated with a more rapid decline in FEV1 were female gender, smoking and prolonged eosinophilic airway inflammation.	15898981
Inflammation, Asthma	Altered Intercellular Communication	The site and distribution of inflammation in the airways of asthmatic patients has been largely investigated.	15898982
Asthma, Pneumonitis	Altered Intercellular Communication	It has been demonstrated that distal lung inflammation in asthma may significantly contribute to the pathophysiology of the disease.	15898982
Inflammation	Altered Intercellular Communication	The upper airways have also been implicated in the overall asthmatic inflammation.	15898982
Asthma, Pneumonitis	Altered Intercellular Communication	Although it is now accepted that lung inflammation is not restricted to the intrapulmonary airways in asthma, little is known about cell distribution in the other lung compartments and their relation to the intrapulmonary airways.	15898982
Inflammation	Altered Intercellular Communication	There is a localized distribution of alveolar inflammation at the peribronchiolar region for mast cells and neutrophils.	15898982
Inflammation	Altered Intercellular Communication	These results demonstrate that microparticles might modulate the release of chemokines and cytokines by FLS and might therefore have a function in synovial inflammation and angiogenesis.	15899040
Inflammation	Altered Intercellular Communication	The AcrySof SA30AL maintains good centration, produces minimal inflammation, and is well tolerated in the pediatric eye.	15899453
Inflammation, Fibrosis Assessment, Edema	Altered Intercellular Communication	Dominant and secondary patterns, respectively, were as follows: stromal retraction, 30 (50%) and 4 (7%); edema, 18 (30%) and 1 (2%); inflammation, 8 (13%) and 14 (23%); fibroblastic proliferation, 3 (5%) and 5 (8%); fibrosis, 1 (2%) and 4 (7%).	15899775
Inflammation, Fibrosis Assessment, Edema	Altered Intercellular Communication	Progression occurred in 21 cases, including 9 (30%) of 30 with stromal retraction, 8 (45%) of 18 with edema, 2 (25%) of 8 with inflammation, 1 (33%) of 3 with fibroblastic proliferation, and 1 (100%) of 1 with fibrosis.	15899775
Inflammation	Altered Intercellular Communication	The prototypic marker of inflammation is C-reactive protein (CRP).	15899961
Inflammation, vascular inflammations	Altered Intercellular Communication	This systemic inflammatory phenotype may contribute to vascular inflammation or may reflect inflammation in vessels or at other sites.	15899961
Osteomyelitis, Inflammation, Ulcer	Altered Intercellular Communication	Diagnosing osteomyelitis in patients with pressure ulcers is complicated by overlying soft-tissue inflammation and reactive bone formation.	15900150
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	To compare the efficacy of a dietary combination (portfolio) of cholesterol-lowering foods vs a statin in reducing C-reactive protein (CRP) as a biomarker of inflammation linked to increased cardiovascular disease risk.	15900306
Inflammation, Periodontitis	Altered Intercellular Communication	The purpose of the study has been to evaluate the degree of chronic inflammation in tissues surrounding the apex of the tooth root in patients with apical periodontitis in the remission phase.	15900705
Granuloma, Inflammation	Altered Intercellular Communication	The material included 37 apical granulomas and radicular cysts obtained as a result of apiectomy, and 20 teeth which were removed together with the focus of the periapical inflammation.	15900705
Inflammation	Altered Intercellular Communication	Despite the absence of clinical symptoms in 23 of 57 cases, the morphological signs of chronic inflammation were observed in the apical area of the tooth root.	15900705
Inflammation	Altered Intercellular Communication	Asthma is characterized by both chronic inflammation and remodeling of the airways.	15901607
Inflammation	Altered Intercellular Communication	Proteases are important mediators of inflammation, cytokine activation, and tissue remodeling.	15901607
Inflammation, Asthma	Altered Intercellular Communication	Proteolytic enzyme activity in asthma is dependent on the underlying inflammatory phenotype and is differentially regulated with MMP-9 activity a feature of eosinophilic inflammation, and active NE in neutrophilic inflammation.	15901607
Inflammation, Muscle Fatigue	Altered Intercellular Communication	The influence of celecoxib on muscle fatigue resistance and mobility in elderly patients with inflammation.	15903281
Communicable Diseases, Muscle Fatigue	Altered Intercellular Communication	The results of this study suggest that COX-2-selective inhibition has a beneficial effect on muscle fatigue resistance in hospitalized elderly patients with acute inflammation of infectious origin.	15903281
Inflammation, Atheroma, Atherosclerosis	Altered Intercellular Communication	Evidence concerning the role of inflammation in atheroma formation has been derived from several models of atherosclerosis.	15905893
Inflammation, Vascular Diseases	Altered Intercellular Communication	Inflammation should exert its adverse vascular effects by structural changes in the artery wall and consequently alterations in arterial elasticity, which could be detected already in asymptomatic early vascular disease.	15905893
Arterial Stiffness, Inflammation	Altered Intercellular Communication	Therefore, we examined the association between arterial stiffness of large and small arteries and inflammation in an asymptomatic population referred for primary prevention cardiovascular screening.	15905893
Inflammation	Altered Intercellular Communication	In conclusion, these findings support the hypothesis that hsCRP, a marker for acute and low-grade inflammation, is associated with large artery but not with small artery elasticity in asymptomatic individuals undergoing primary prevention cardiovascular screening.	15905893
Corneal Endothelial Cell Loss, Necrosis	Altered Intercellular Communication	It is characterised by segmental angiocentric neutrophilic inflammation, endothelial cell damage and fibrinoid necrosis.	15906029
Pain Distress Question, Inflammation, Traumatic injury	Altered Intercellular Communication	The technique of lying open of sinus tract using radio surgery technique resulted in achieving less tissue trauma, pain and inflammation.	15906911
Arthritis, Infectious, Lyme Arthritis, Lymphadenopathy, Edema, Myositis, CTCAE 5.0	Altered Intercellular Communication	Our results identified three MRI features, specifically, myositis, adenopathy, and lack of subcutaneous edema, that strongly suggest the diagnosis of Lyme arthritis rather than septic arthritis in children with acute inflammation of the knee.	15908551
methyldopa, Communicable Diseases, Inflammation	Altered Intercellular Communication	These data indicate that a pathogen capable of inducing chronic inflammation and pro-angiogenic cytokines can be detected in some AMD CNV, and suggest that infection may contribute to the pathogenesis of AMD.	15909160
Inflammation	Altered Intercellular Communication	The disease is characterized by episodic inflammation of cartilage such as auricular, nasal and laryngotracheal.	15909247
Inflammation	Altered Intercellular Communication	Both C-reactive protein (CRP) and ferritin have been reported to reflect the extent of oxidative stress and inflammation in individual patients and may be useful markers of disease activity and mortality risk.	15909479
Follicular hyperplasia, Granulomatous inflammation	Altered Intercellular Communication	Results confirmed a recognizable cytologic picture of reactive hyperplasia of follicular center cells and granulomatous inflammation, with a unique finding of Toxoplasma gondii tachyzoite in lymphatic cells.	15909891
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	GSH was an independent negative predictor of portal/periportal inflammation (P = 0.02) and fibrosis (P = 0.01).	15910488
Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Whole blood GSH and plasma vitamin C are negatively associated with hepatic portal/periportal inflammation and fibrosis stage in CHC.	15910488
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is important in the pathogenesis of atherosclerosis.	15910853
Tracheitis	Altered Intercellular Communication	Bronchoscopy revealed progressive tracheal inflammation necessitating an urgent tracheotomy.	15911023
Inflammation	Altered Intercellular Communication	High-grade inflammation still continued after the operation and computerized tomography revealed the increase of high density area.	15912785
Inflammation, Fever	Altered Intercellular Communication	Inflammation and pyrexia did not improve until we changed antibiotics from IPM/CS to amikacin sulfate.	15912785
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	Local inflammation and MMP-9 levels slightly increased with age in plaques obtained from patients suffering from haemodynamically significant advanced atherosclerotic lesions.	15914297
Airway structure, Asthma	Altered Intercellular Communication	There were no significant differences in other markers of asthma control, use of oral prednisone, pulmonary function, or levels of airway inflammation (sputum eosinophils).	15914548
Inflammation, Carcinogenesis, Ulcerative Colitis, Primary malignant neoplasm	Altered Intercellular Communication	Although regenerating gene (REG) Ialpha protein may be involved in the inflammation and carcinogenesis in the gastrointestinal tract, its pathophysiological role in ulcerative colitis (UC) and the resulting colitic cancer remains unclear.	15914572
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The level of REG Ialpha mRNA expression in UC tissues correlated significantly with severity of inflammation and disease duration.	15914572
Inflammation, Primary Biliary Cholangitis, Autoimmune Disorder, CTCAE, Liver Failure, Intrahepatic bile duct, Cicatrization, Liver Cirrhosis	Altered Intercellular Communication	Primary biliary cirrhosis (PBC) is a rare, autoimmune liver disorder characterized by progressive destruction of intrahepatic bile ducts, that results in portal inflammation, scarring, cirrhosis and, eventually, liver failure.	15915245
Tuberculoma, Granulomatous inflammation	Altered Intercellular Communication	A biopsy was obtained endoscopically via a transnasal approach, revealing a granulomatous inflammation with acid-fast rods and thus confirming the diagnosis of a tuberculoma.	15915344
HD Term Type, Inflammation, Hepatitis C	Altered Intercellular Communication	Hepatitis C (HCV) is not an uncommon feature in hemodialysis (HD) patients and may be a cause of systemic inflammation.	15917961
HD Term Type, Inflammation, Hepatitis C	Altered Intercellular Communication	The lower hsCRP/IL-6 ratio in HCV+ patients than in HCV- patients suggests that hsCRP may be a less useful marker of inflammation in HCV+ patients and that a different cut-off value for hsCRP for this population of patients on HD may be required to define inflammation.	15917961
Inflammation, Retinal Diseases, Endothelial dysfunction	Altered Intercellular Communication	Inflammation and endothelial dysfunction are associated with retinopathy: the Hoorn Study.	15918015
Inflammation, Retinal Diseases, diabetic	Altered Intercellular Communication	The exact pathogenesis of retinopathy in diabetic and non-diabetic individuals is incompletely understood, but may involve chronic low-grade inflammation and dysfunction of the vascular endothelium.	15918015
Endothelial dysfunction, Inflammation, Retinal Diseases, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The aim of this study was to investigate the association of inflammation and endothelial dysfunction with prevalent retinopathy in individuals with and without type 2 diabetes.	15918015
Inflammation, Neoplasms, Necrosis	Altered Intercellular Communication	Imatinib mesylate has been shown to decrease the density of tumor cells without causing inflammation or necrosis.	15918651
Drug-Induced Liver Disease, Inflammation, Liver Cirrhosis	Altered Intercellular Communication	Histological examination showed essentially normal liver tissue; there was no evidence of any excess inflammation and no features to suggest cirrhosis or drug-induced liver disease.	15918892
Interstitial inflammation	Altered Intercellular Communication	There was a trend toward an increase in the score of interstitial inflammations in the CsA group, while it remained constant in the FK cohort (P = .05 at 1 year between the two groups).	15919455
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Our results suggest that magnesium intake is inversely associated with systemic inflammation and the prevalence of the metabolic syndrome in middle-aged and older women.	15920065
Inflammation, Squamous metaplasia	Altered Intercellular Communication	Simplex squamous metaplasia is a common finding probably related to chronic inflammation.	15920559
Inflammatory abnormality of the eye	Altered Intercellular Communication	Disease progression, control of ocular inflammation with systemic immunosuppression, the incidence of mucocutaneous lesions, and surgical intervention were also assessed.	15921743
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	For the outcome of treatment the direct effects of NSAIDs on cartilage may be more important than indirect effects on inflammation, considered being secondary in OA.	15922186
Strabismus	Altered Intercellular Communication	Orbital tissues from 30 patients with TAO were compared with those of 20 patients with strabismus and four with non-thyroid orbital inflammation.	15923509
Thyroid associated opthalmopathies, Orbital Pseudotumor	Altered Intercellular Communication	Disease activity is the main determinant for the management of Graves' ophthalmopathy, but treatments are often symptomatic, aiming at decreasing orbital inflammation.	15924092
Inflammation, Radicular pain	Altered Intercellular Communication	Transforaminal injection of steroids has gained popularity due to the rationale that inflammation of the spinal nerve roots causes radicular pain, and therefore steroids placed locally should relieve symptoms.	15924210
Communicable Diseases, Inflammation	Altered Intercellular Communication	Inflammation and infection are involved in both diseases.	15925417
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Immune activation and inflammation contribute to the progression of chronic heart failure (CHF), but therapeutic approaches directed against these processes have been largely unsuccessful.	15925562
Inflammation, Damage	Altered Intercellular Communication	We questioned whether high avidity leads to persistent deposition of anti-GBM antibodies, thereby perpetuating inflammation and renal damage.	15925834
Inflammation, Lipolysis, Necrosis	Altered Intercellular Communication	The pancreatic enzyme lipase may induce lipolysis and fat necrosis with secondary tissue inflammation.	15926039
Gingivitis	Altered Intercellular Communication	She was referred to the Department of Periodontology for treatment of severe gingival inflammation.	15926446
Proteinuria, Inflammation, Hypertension, CTCAE, Lipids abnormal	Altered Intercellular Communication	The prevalence of renal and cardiovascular risk factors including proteinuria, hypertension, lipid abnormalities and markers of inflammation was higher among those with low eGFR than age-matched controls.	15928100
Disorder of eye, Orbital Pseudotumor	Altered Intercellular Communication	Adipocyte-related IEGs are overexpressed in active ophthalmopathy, and CYR61 may have a role in both orbital inflammation and adipogenesis and serve as a marker of disease activity.	15928252
Inflammation	Altered Intercellular Communication	Persistent isolated inflammation of the sphenoid sinus, an entity that is not diagnosed very often, poses a challenge to clinicians and researchers alike.	15929324
Acute and chronic inflammation	Altered Intercellular Communication	We discuss the potential for this ubiquitous gastric bacterium to play a role in at least some forms of chronic sinonasal inflammation.	15929324
Inflammation, Dental Plaque	Altered Intercellular Communication	These variations may be related to inflammation of vulnerable plaque.	15929386
Candidemia, Inflammation, Pancreatitis, Chorioretinitis	Altered Intercellular Communication	A 63-year-old female with candidemia following necrotizing pancreatitis developed clinical signs of chorioretinitis and underwent the systemic administration of voriconazole, after which anterior chamber inflammation and multiple, white, fluffy, chorioretinal lesions, under 1mm in diameter, were gradually resolved and visual acuity improved.	15929491
Asthma, Pneumonitis	Altered Intercellular Communication	Alveolar nitric oxide in adults with asthma: evidence of distal lung inflammation in refractory asthma.	15929952
Pneumonitis	Altered Intercellular Communication	Recent studies have suggested that alveolar nitric oxide (NO) concentration is a noninvasive test of distal lung inflammation.	15929952
Airway structure, Asthma, Pneumonitis	Altered Intercellular Communication	In conclusion, these findings support the hypothesis that alveolar nitric oxide is a measure of distal airway inflammation and suggest that distal lung inflammation is present in refractory asthma.	15929952
Intraocular inflammation, Postoperative Complications, Glaucoma, CTCAE, Choroidal Detachment	Altered Intercellular Communication	Postoperative complications included intraocular inflammation with choroidal detachment, secondary glaucoma, and persistent epithelial defect after surgery.	15931549
Inflammation, Strabismus	Altered Intercellular Communication	Twice-daily 0.1% topical dexamethasone eye drops control inflammation after strabismus surgery as effectively as four-times-daily dosage, but induces less increase in IOP, and may be a better treatment schedule.	15932528
Inflammation, Atherosclerosis	Altered Intercellular Communication	Prognostic impact of fibrinogen in carotid atherosclerosis: nonspecific indicator of inflammation or independent predictor of disease progression?	15933258
Craniosynostosis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The study group consisted of 38 patients with a history of at least one endoscopic sinus surgery (ESS) with continued CRS symptoms and mucosal inflammation on endoscopy.	15933499
Inflammation, Craniosynostosis	Altered Intercellular Communication	The first control group consisted of 10 patients who had at least one ESS procedure and had no symptoms of CRS or mucosal inflammation a minimum of 1 year postoperatively.	15933499
Inflammation, Acinar Cell, Fibrosis Assessment, Metaplasia	Altered Intercellular Communication	In the chemoradiated glands, light microscopic findings included pronounced acinar cell loss with accompanying ductal metaplasia and ductal proliferation and increased fibrosis, chronic inflammation, nuclear atypia, and cytoplasmic vacuolization when compared with controls.	15933500
Inflammation, Esophageal food impaction	Altered Intercellular Communication	Association of eosinophilic inflammation with esophageal food impaction in adults.	15933677
Inflammation	Altered Intercellular Communication	Of the 272 patients, 11 (4.0 %) showed chronic inflammation in the angulus biopsy only.	15933925
Inflammation	Altered Intercellular Communication	Of the 152 patients with a normal-looking mucosa at the angulus, only six (3.9 %) showed the histological changes of chronic inflammation in the angulus alone.	15933925
Refractory anemias, Rheumatoid Arthritis, Inflammation, Necrosis	Altered Intercellular Communication	Use of anti-tumor necrosis factor (anti-TNF) antibody therapy in rheumatoid arthritis (RA) has expanded our understanding of possible mechanisms by which this treatment reduces inflammation.	15934093
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	Although the capacity for the cortisone-cortisol shuttle was higher in synovial cells from less-inflamed OA tissue compared with inflamed RA tissue, it was obvious that synovial inflammation in RA, but not OA, was related positively to the reactivation of cortisone.	15934114
Inflammation, Cocaine-Related Disorders, Osteoporosis, Atherosclerosis, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Cholesterol synthesis is the trigger and isoprenoid dependent interleukin-6 mediated inflammation is the common causative factor and therapeutic target for atherosclerotic vascular disease and age-related disorders including osteoporosis and type 2 diabetes.	15935563
Inflammation, Cocaine-Related Disorders, Osteoporosis, Atherosclerosis, Presenile dementia, "Alzheimers Disease", Coronary Artery Disease, Peripheral Vascular Diseases, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	IL-6 inflammation is the common causative origin for atherosclerosis, peripheral vascular disease, coronary artery disease, and age-related disorders including osteoporosis, dementia, Alzheimer's disease and type 2 diabetes.	15935563
Refractory anemias, Inflammation	Altered Intercellular Communication	The study group consisted of 32 patients with RA followed up clinically and by ultrasound using the resistive index (RI) measurements in the patients' wrists as indicator of inflammation.	15936489
Inflammation, Coronary Arteriosclerosis, Hypertrophy	Altered Intercellular Communication	C-reactive protein, a marker of systemic inflammation, and ECG STD, an index of myocardial ischemia and hypertrophy, independently predict mortality.	15936607
Inflammation, Heart failure	Altered Intercellular Communication	Inflammation, as measured by the erythrocyte sedimentation rate, is an independent predictor for the development of heart failure.	15936609
Inflammation, Heart failure	Altered Intercellular Communication	Our objective was to explore inflammation, measured as erythrocyte sedimentation rate (ESR), as a predictor for the development of heart failure (HF).	15936609
Inflammation	Altered Intercellular Communication	In recent years, evidence of the importance of inflammation in the pathophysiology of HF has emerged, and various inflammatory markers have been found to predict future HF.	15936609
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Within the lungs of patients with severe emphysema, inflammation continues despite smoking cessation.	15937291
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Severe emphysema is associated with inflammation involving T lymphocytes that are composed of oligoclonal CD4+ T cells.	15937291
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	These T cells are accumulating in the lung secondary to conventional antigenic stimulation and are likely involved in the persistent pulmonary inflammation characteristic of severe emphysema.	15937291
Inflammation, Impaired, Hereditary	Altered Intercellular Communication	The results suggest that severe vascular impairment and mild inflammation contribute to the slow but inexorable progression of hereditary brain calcinosis.	15937691
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Acute-phase markers of inflammation and glomerular structure in patients with type 2 diabetes.	15938041
Diabetic Nephropathy, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Type 2 diabetes is frequently associated with an inflammatory status; the relationships between low-grade inflammation and diabetic nephropathy are still unclear.	15938041
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The aim of this study was to evaluate the relationships between acute-phase markers of inflammation, glomerular structure, and albumin excretion rate (AER) in type 2 diabetes.	15938041
Nodular glomerulosclerosis, Inflammation, Kidney Diseases, Thickened	Altered Intercellular Communication	In conclusion, this study demonstrates that acute-phase markers of inflammation are associated with nephropathy status and GBM thickening, suggesting a role for inflammation in the pathogenesis of diabetic glomerulopathy.	15938041
Kidney Failure, Chronic	Altered Intercellular Communication	Inflammation markers, adhesion molecules, and all-cause and cardiovascular mortality in patients with ESRD: searching for the best risk marker by multivariate modeling.	15938042
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Inflammation is a major risk factor for mortality and cardiovascular (CV) complications in patients with ESRD.	15938042
Acute Lung Injury, Inflammation	Altered Intercellular Communication	The acute lung injury (ALI) is defined as the inflammation syndrome and increased permeability, which is associated with radiological and physiological disorders.	15938219
Inflammation, Neoplasms, Lymphatic Vessel Tumors	Altered Intercellular Communication	In inflammation and in lymphatic tumors, tumor antigens levels remained normal.	15938530
Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	HA concentrations in the serum of CHC patients with mild to severe inflammation and fibrosis (F1 and F3) were normal (100 ng/ml).	15938533
Inflammation, Hemorrhage, Glaucoma, CTCAE, Traumatic injury	Altered Intercellular Communication	Five different types of early secondary glaucoma associated with trauma were determined by clinical findings: hemorrhage type, chamber angle injury type, lens related type, synechia and proliferation type, and inflammation type.	15938810
Inflammation, Periodontal Diseases	Altered Intercellular Communication	The volatile fatty acids, especially succinic acid, propionic acid, butyric acid and valeric acid were associated significantly with the severity and inflammation of periodontal disease.	15938880
Inflammation, Metabolic Syndrome X, Cardiovascular Diseases	Altered Intercellular Communication	Insulin resistance and the metabolic syndrome showed significant associations with markers of haemostasis and inflammation, which may be relevant to their associations with cardiovascular disease.	15939060
Inflammation, Thrombosis	Altered Intercellular Communication	Common promoter polymorphisms of inflammation and thrombosis genes and longevity in older adults: the cardiovascular health study.	15939070
Inflammation, Atherosclerosis	Altered Intercellular Communication	Subclinical COX- and cytokine-mediated inflammation and oxidative stress are ongoing processes not only in active smokers but also in former smokers which may contribute to the accelerated atherosclerosis associated with smoking.	15939073
Airway structure	Altered Intercellular Communication	However, the pathogenesis of the airway inflammation remains unclear.	15939254
Inflammation	Altered Intercellular Communication	The failure of non-inflammatory removal of emigrating neutrophils due to delayed apoptosis has been proposed as a mechanism by which the neutrophilic inflammation persists.	15939254
Inflammation, Endothelial dysfunction, Macular degeneration	Altered Intercellular Communication	Systemic markers of inflammation, endothelial dysfunction, and age-related maculopathy.	15939388
Inflammation, AKR1A1 wt Allele, Endothelial dysfunction	Altered Intercellular Communication	Contrary to other reports, we cannot confirm a strong or consistent relationship of markers of inflammation and endothelial dysfunction with ARM.	15939388
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	No features displayed high agreement; substantial agreement was only seen for steatosis grade; moderate agreement for hepatocyte ballooning and perisinusoidal fibrosis; fair agreement for Mallory bodies; acidophilic bodies and lobular inflammation displayed only slight agreement.	15940625
Inflammation	Altered Intercellular Communication	These results provide initial evidence for a role of adhesion molecules and systemic inflammation in TS, and support the hypothesis of an ongoing immune-mediated process in this condition.	15941572
Inflammation, Arthropathy	Altered Intercellular Communication	To determine whether calcium pyrophosphate dihydrate (CPPD) crystals can be found in the synovial fluid of non-inflamed joints in patients with CPPD related arthropathy; if so, to determine whether they interact with cells and produce subclinical inflammation in this setting.	15941838
Inflammation	Altered Intercellular Communication	The raised cell counts and percentage of PMN suggest mild subclinical inflammation in these joints.	15941838
Coronary Artery Disease, Diabetes Mellitus	Altered Intercellular Communication	Furthermore, we provide insight into the severe form of coronary artery disease associated with diabetes, reporting an overabundance of immune and inflammatory signals in diabetics.	15942018
Inflammation	Altered Intercellular Communication	Tubular TGF-beta1 immunostaining was significantly higher in biopsies with inflammatory cellular infiltration compared those without inflammation (p = 0.0048).	15942255
Presenile dementia, Inflammation	Altered Intercellular Communication	Inflammation plays a part in the etiology of dementia.	15942327
Sepsis, Inflammation	Altered Intercellular Communication	Platelet-activating factor (PAF) is a potent proinflammatory mediator in systemic inflammation and sepsis and is inactivated by the enzyme PAF-acetylhydrolase (PAF-AH).	15942364
Pain Distress Question, Inflammation, Swelling, Lymphoproliferative Disorders, Exophthalmos	Altered Intercellular Communication	The typical presentation of adnexal lymphoproliferative disease is with a painless mass, swelling, or proptosis; however, pain and inflammation occurred in 20% and 30% of patients, respectively.	15942490
Inflammation, Cap polyposis	Altered Intercellular Communication	Histologically, there was transmural inflammation with a thickened proper muscular layer overlaid by inflammatory polyposis.	15942721
Inflammation	Altered Intercellular Communication	An intraoperative frozen section of the cyst wall showed a fibrous wall with acute and chronic inflammation without an epithelial lining.	15943401
Inflammation, Cachexia	Altered Intercellular Communication	Systemic inflammation correlates with increased expression of skeletal muscle ubiquitin but not uncoupling proteins in cancer cachexia.	15944798
Inflammation, Hypermetabolism, Pancreatic carcinoma	Altered Intercellular Communication	We investigated markers of systemic inflammation, hypermetabolism and expression of ubiquitin and uncoupling proteins 2 and 3 in muscle of pancreatic cancer patients.	15944798
Inflammation, Weight decreased	Altered Intercellular Communication	Weight loss correlated with systemic inflammation and ubiquitin 1.2 and 2.4 kb mRNA expression.	15944798
Inflammation, Weight decreased, Pancreatic carcinoma	Altered Intercellular Communication	Weight loss in pancreatic cancer is associated with systemic inflammation and increased mRNA expression for ubiquitin but not uncoupling proteins in skeletal muscle.	15944798
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	The presence of glycogen nuclei was significantly correlated with steatosis (P=0.000), lobular inflammation (P=0.019) and perisinusoidal fibrosis (P=0.000).	15946458
Inflammation, Fibrosis Assessment, Fatty degeneration, Diabetes Mellitus, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	1) Liver biopsy taken at gastric bypass reveals different types of NAFLD; 2) Diabetes type 2 is associated with NAFLD type 4; 3) Glycogen nuclei are correlated with steatosis, lobular inflammation and perisinusoidal fibrosis; 4) Steatosis represents the basic injury in NAFLD and is associated with hepato-cellular ballooning.	15946458
Pain Distress Question, Neurogenic Inflammation, Small Fiber Neuropathy	Altered Intercellular Communication	Five patients with small-fibre neuropathy characterized by temperature-dependent spontaneous pain, hyperalgesia/allodynia and signs of neurogenic inflammation were studied clinically and thermographically, and by microneurography.	15947060
Airway structure, ARCN1 gene	Altered Intercellular Communication	Nitrosative stress, heme oxygenase-1 expression and airway inflammation during severe exacerbations of COPD.	15947302
Airway structure, ARCN1 gene	Altered Intercellular Communication	The aim of this study was to examine the relationship between airway inflammation, nitrosative stress, heme-oxygenase expression, and acute severe exacerbations of COPD.	15947302
Inflammation, Exacerbation	Altered Intercellular Communication	Future therapeutic strategies may aim at regulating inflammation and NO synthesis during COPD exacerbations.	15947302
Communicable Diseases, Inflammation	Altered Intercellular Communication	GM-CSF infusion up-regulated the functional markers of inflammation on circulating neutrophils and monocytes and was associated with both the clinical and microbiological resolution of infection.	15947332
Airway structure, Inflammation, Asthma, Bronchoconstriction	Altered Intercellular Communication	Leukotrienes play a role in inflammation, and their participation in airway inflammation and bronchoconstriction in patients with severe asthma can be ameliorated by a new class of drugs known as leukotriene modulators.	15947555
Inflammation	Altered Intercellular Communication	It is of practical importance for histopathological diagnosis that inflammation in autoimmune enteric leiomyositis affects the muscularis propria of the small intestine, whereas mucosa and submucosa do not show severe inflammatory changes.	15948126
Inflammation	Altered Intercellular Communication	SP-D protein levels are increased at sites of inflammation in the prostate, suggesting SP-D may also contribute more generally to inflammatory regulation in the prostate.	15948134
Inflammation, Traumatic injury	Altered Intercellular Communication	Interleukin (IL)-8 is a pro-inflammatory cytokine of host response to injury and inflammation.	15948980
Inflammation, Malnutrition, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Kidney Diseases	Altered Intercellular Communication	CKD is associated with nontraditional risk factors for the development of CVD, including chronic inflammation, malnutrition and calcium-phosphate disorders.	15949381
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Kallikrein-kinin system in inflammatory bowel diseases: Intestinal involvement and correlation with the degree of tissue inflammation.	15949977
Inflammation	Altered Intercellular Communication	Tissue kallikrein and its natural inhibitor, kallistatin, play opposite roles in the generation of bradykinin, a potent mediator of inflammation.	15949977
Inflammation	Altered Intercellular Communication	The kallikrein and kallistatin depletion of goblet cells and the increased interstitial kallikrein and kallistatin reactivity correlated with the degree of tissue inflammation (p=0.0001).	15949977
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Kallikrein-kinin system is actively involved in inflammatory bowel disease as a result of the release of kallikrein in the intestinal extracellular space; this involvement correlates with the degree of tissue inflammation.	15949977
Inflammation, Squamous intraepithelial lesion	Altered Intercellular Communication	The results indicate that about 10% of women who show a negative Pap smear, but have inflammation are positive for high-risk HPV types 16/18 and about 15% harbor squamous intra-epithelial lesions.	15950365
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Necrotizing granulomatous inflammation was seen on meningeal and brain biopsy.	15951415
Pneumothorax, Endometriosis	Altered Intercellular Communication	Pneumothorax unrelated to the hormonal cycle occurred by pulmonary endometriosis.	15952324
Inflammation, Scleritis	Altered Intercellular Communication	Scleritis is a painful inflammation of the sclera that is often difficult to treat.	15953441
Airway structure, Asthma	Altered Intercellular Communication	It has been suggested that dendritic cells (DCs) are critical antigen presenting cells for eosinophilic airway inflammation in a mouse model of asthma, and cysteinyl leukotrienes may play a role in DC trafficking in asthmatics.	15953857
Airway structure, Inflammation, Atopy	Altered Intercellular Communication	We demonstrated that the increased number of DCs was evident in the induced sputum of both atopic and nonatopic asthmatics, and the DC number was related to the activated eosinophil count, which suggests that DCs may contribute to the ongoing eosinophilic inflammation in asthmatic airways, and vice versa.	15953857
Inflammation, Communicable Diseases, Varicose Ulcer, Skin loss, Burn injury	Altered Intercellular Communication	Two of the patients were treated for a varicose ulcer on a lower extremity, two patients for loss of skin after an inflammation secondary to infection, one high-risk patient for deep burns, and one patient for a deep defect caused by an inappropriate medical care.	15954460
Mucosal erosion, Inflammation	Altered Intercellular Communication	Endoscopic examination of the stomach and duodenum showed multiple sessile polyps and mucosal erosion associated with evidence of chronic inflammation.	15954520
PALATAL INFLAMMATION	Altered Intercellular Communication	Two denture-wearing patients, both with palatal inflammation diagnosed as Newton type II denture stomatitis were treated with low-power semiconductor diode laser (BTL-2000, Prague, Czech Republic) at different wavelengths (685 and 830 nm) for 5 d consecutively.	15954824
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Biomarkers of inflammation and progression of chronic kidney disease.	15954913
Inflammation, Renal function, Injury of kidney	Altered Intercellular Communication	Although inflammation may mediate progressive renal injury, the relation between statin use, markers of inflammation, and the rate of kidney function loss has not been elucidated.	15954913
Inflammation, Renal function	Altered Intercellular Communication	Pravastatin appears to prevent loss of kidney function to a greater extent in individuals with greater evidence of inflammation, although this was of borderline significance.	15954913
Inflammation, Renal function, Chronic Kidney Diseases, Coronary heart disease	Altered Intercellular Communication	These data suggest that inflammation may mediate the loss of kidney function among subjects with chronic kidney disease and concomitant coronary disease.	15954913
Chronic inflammation	Altered Intercellular Communication	His serological data was not particular and he did not suffer with chronic inflammation.	15955172
Cessation of life, Hypoalbuminemia	Altered Intercellular Communication	Hypoalbuminaemia is a marker of malnutrition-inflammation complex syndrome (MICS) and a strong predictor of cardiovascular (CV) death in maintenance haemodialysis (MHD) patients.	15956056
Inflammation, Impaired	Altered Intercellular Communication	Moreover, we assessed whether the serum level of C-reactive protein (CRP), a marker for systemic inflammation, was associated with cellular impairment of EPCs.	15956081
Inflammation, Endothelial dysfunction, Pre-Eclampsia	Altered Intercellular Communication	Depletion and cellular aging of EPCs in patients with preeclampsia might be associated with endothelial dysfunction and could be affected by systemic inflammation.	15956081
Inflammation	Altered Intercellular Communication	We analyzed parameters of inflammation such as: activity of serum chitotriosidase by fluorimetric assay, C-reactive proteins (CRP), number of white body cells (WBCs), IgG and fibrinogen.	15956787
Inflammation	Altered Intercellular Communication	In our study, we observed a statistically significant difference (p < 0.05) in the activity of most parameters of inflammation.	15956787
Inflammation	Altered Intercellular Communication	We recently reported that oxidative stress elicited by chronic inflammation increases the mutation of mitochondrial DNA (mtDNA) and possibly correlates with precancerous status.	15956973
Inflammation	Altered Intercellular Communication	The present observations suggest that the injury followed by the regeneration of colorectal mucosal cells associated with chronic inflammation causes accumulation of mtDNA mutations.	15956973
Nephritis	Altered Intercellular Communication	Determination of urinary MCP-1 level is beneficial to know the degree of kidney inflammation in DN patients.	15957833
Inflammation, Atherosclerosis	Altered Intercellular Communication	Serum and peripheral blood mononuclear cells infectious burden: correlation to inflammation and atherosclerosis in haemodialysis patients.	15958038
Communicable Diseases, Inflammation, atherosclerotic, Atherosclerosis	Altered Intercellular Communication	Although inflammation correlates to atherosclerosis, neither PBMC nor the serum infectious burden is associated with these two entities in the inflamed and atherosclerotic HD patients.	15958038
allergic inflammation	Altered Intercellular Communication	Recent studies have suggested that not only alphabeta(+) T cells, but also the less common gammadelta(+) T cells may play a role as effectors and immunoregolatory cells in the development and perpetuation of allergic inflammation.	15958077
Inflammation, neutrophil degranulation	Altered Intercellular Communication	We have shown recently that patients in stable remission have increased circulating levels of PR3, independent of autoantibody titre, inflammation, neutrophil degranulation and renal function.	15958084
Inflammation, MEFV gene, Brucellosis	Altered Intercellular Communication	Pyrin is a newly recognised intracellular regulator of inflammation, and mutations in MEFV, the gene encoding pyrin, are the cause of familial Mediterranean fever.	15958759
Inflammation, Dysplasia, Traumatic injury	Altered Intercellular Communication	These changes appear to represent a nonspecific, possibly degenerative response to inflammation and injury, and should be distinguished from dysplasia.	15958856
Focal acute inflammation	Altered Intercellular Communication	Ulcerative superficial necrosis with venous haemorragic swarm and focal acute pseudomembranous inflammation.	15960363
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	The course after stroke was different between the parameters of inflammation.	15961109
Inflammation, Coronary microvascular dysfunction, Coronary Arteriosclerosis	Altered Intercellular Communication	In patients with CAD, evidence of systemic inflammation is independently associated with endothelium-dependent and endothelium-independent coronary microvascular dysfunction, which, in turn, may be critical to precipitate myocardial ischaemia, in particular, in unstable patients.	15961409
Inflammation, Malignant Neoplasms, Neoplasms	Altered Intercellular Communication	Tl-201 scintigraphy was performed in 146 patients (129 with malignant tumours, ten with benign tumours and seven with inflammation).	15961594
vascular inflammations	Altered Intercellular Communication	Flow-mediated dilation in the brachial artery, serum markers of iron stores, vascular inflammation and oxidative stress, and cardiac risk factors were assessed in all subjects.	15961703
vascular inflammations	Altered Intercellular Communication	Serum biomarkers of vascular inflammation did not differ between groups but 3-nitrotyrosine, a marker of oxidative stress, was decreased in high-frequency donors when compared with low-frequency donors.	15961703
Inflammation	Altered Intercellular Communication	Epidemiological data demonstrate an association between systemic low-grade inflammation defined as 2- to 3-fold increases in circulating inflammatory mediators and age-related decline in cognitive function.	15963684
Inflammation	Altered Intercellular Communication	We investigated changes in emotional, cognitive, and inflammatory parameters in an experimental in vivo model of low-grade inflammation.	15963684
Infarction, prostatitis	Altered Intercellular Communication	Do prostatic infarction, prostatic inflammation and prostate morphology play a role in acute urinary retention?	15964132
Infarction, prostatitis	Altered Intercellular Communication	To investigate whether there is a role of prostatic infarction, prostatic inflammation and prostate morphology in acute urinary retention (AUR) etiology.	15964132
Infarction, prostatitis	Altered Intercellular Communication	Prostatic infarction, prostatic inflammation and prostatic morphology were examined in the patients' specimen.	15964132
prostatitis	Altered Intercellular Communication	Mean age, median serum prostate-specific antigen (PSA) level, and prostatic inflammation ratio were significantly higher in Group 1.	15964132
Cardiovascular Diseases, prostatitis	Altered Intercellular Communication	In the present study, except for taking previous general anesthesia and preexisting cardiovascular disease, only prostatic inflammation was found important contributory factor on AUR.	15964132
prostatitis	Altered Intercellular Communication	AUR risk was 3.03 times higher in the patients with prostatic inflammation (95%CI 1.28-7.15) (p = 0.01).	15964132
prostatitis	Altered Intercellular Communication	Prostatic inflammation may have an important risk factor in AUR etiology.	15964132
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Modulation of neutrophil and inflammation markers in chronic obstructive pulmonary disease by short-term azithromycin treatment.	15964564
Inflammation	Altered Intercellular Communication	Recently, an elevated level of hs-CRP has been shown to be associated with AF burden, suggesting that inflammation increases the propensity for persistence of AF.	15964643
Inflammation, Tumor necrosis	Altered Intercellular Communication	Inflammation was evaluated by quantifying muscle neutrophil and tumour necrosis factor (TNF)-alpha levels.	15964914
Colonization, Atrophic, Inflammatory disease of mucous membrane, Ulcer	Altered Intercellular Communication	Recurrent ulcer patients were characterized by a significantly higher prevalence of high-grade H. pylori colonization and active mucosal inflammation in the antrum as well as by a lower level of active mucosal inflammation and atrophy in the corpus and a higher serum pepsinogen I level compared with complete vagotomy cases.	15966205
Inflammation, Liver Failure	Altered Intercellular Communication	Relationship between preoperative inflammation and postoperative liver failure warrants further investigations because of potential therapeutic consequences.	15966220
Communicable Diseases, Inflammation	Altered Intercellular Communication	Primary SS can cause serious parotid morbidity secondary to inflammation and infection.	15966471
Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	We examined serum levels of Cu, Fe, Zn and Se, as well as glutathione peroxidase (GPx), a selenoenzyme with antioxidant properties, and C-reactive protein (CRP), a marker of inflammation, in acute coronary syndromes (ACS) regarding their relationship to cardiac troponins and creatine kinase-MB mass (CK-MBm), important prognostic markers.	15966572
Inflammation, Hyperparathyroidism	Altered Intercellular Communication	Our results show that systemic inflammation, secondary hyperparathyroidism and angiotensin system antagonist treatment are the most important modifiable parameters affecting epoetin requirements in stable peritoneal dialysis patients.	15966995
Inflammation, Non-Malignant	Altered Intercellular Communication	A positive linear regression was observed between pSUVs and the grading of inflammation in nonmalignant lesions (p < .05).	15967114
Inflammation	Altered Intercellular Communication	While 73% of patients (n = 11) with sparse inflammation survived, only 47% (n = 7) with moderate and 29% (n = 2) with extensive inflammation survived.	15967913
Inflammation	Altered Intercellular Communication	There is a histologic spectrum with TEN that ranges from sparse to extensive DM inflammation, and degree of inflammation predicts clinical outcome approximately as well as SCORTEN.	15967913
Inflammation, Pain, Postoperative	Altered Intercellular Communication	The additional qualitative observations of a reduction in operation time, postoperative pain, and inflammation augurs for more extensive use of fibrin sealants in ophthalmology.	15968167
Inflammation, Hematoma, Paresthesia, Swelling, Failure (biologic function)	Altered Intercellular Communication	Graft exposure or/and graft removal were defined as failure; hematoma, swelling, inflammation, or temporary paresthesia were defined as complications.	15968184
Inflammatory disease of mucous membrane	Altered Intercellular Communication	The degree of gastric mucosal inflammation may affect the results of CagA serodiagnosis.	15968733
Inflammation, Neoplasms	Altered Intercellular Communication	Macrophage migration inhibitory factor (MIF) was reported to inactivate p53 and play an essential role in the growth and angiogenesis of tumors that arise at sites of chronic inflammation.	15968736
Communicable Diseases, Helicobacter pylori, Stomach Carcinoma, Gastritis	Altered Intercellular Communication	Gastric inflammation is a prerequisite for the development of gastric carcinoma (GC), which has recently been linked to Helicobacter pylori (H pylori) infection.	15968736
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation and symptoms often persist in asthma patients despite treatment with inhaled corticosteroids (ICS) and long-acting beta2-agonists (LABA).	15969886
Inflammation, Postoperative Complications	Altered Intercellular Communication	Systemic inflammation and the activation of the coagulation system following cardiopulmonary bypass (CPB) may contribute to postoperative complications.	15970715
Sjogrens Syndrome", Hyperlipidemia, Inflammation, Xerostomia	Altered Intercellular Communication	We determined appropriate sequence parameters, and then applied the technique to the salivary glands of 143 patients with xerostomia (including those with Sjogren's syndrome or hyperlipidemia) or salivary gland inflammation.	15971185
Inflammation, Sinusitis	Altered Intercellular Communication	Chronic sinusitis is recognized as having a strong inflammatory component, and failures of endoscopic sinus surgery (ESS) are frequently attributed to persistent inflammation.	15971652
Inflammation, Perforation (observation)	Altered Intercellular Communication	In the absence of an intraoperative finding of a perforation or an area of discrete inflammation, copious irrigation and closure of the abdomen is appropriate in cases of diffuse small-bowel diverticulosis.	15972168
HD Term Type, Inflammation	Altered Intercellular Communication	Short-term oral vitamin C supplementation did not modify well-defined oxidative/antioxidative stress and inflammation markers in HD patients.	15972322
Inflammation, Blurred vision, Abscess of pituitary	Altered Intercellular Communication	Blurred vision caused by inflammation of the optic nerves due to a pituitary abscess.	15973069
Inflammation, Blurred vision	Altered Intercellular Communication	The blurred vision was caused by inflammation, but not compression, of the optic nerves due to the pituitary abscess outside the hypophysis.	15973069
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is characterized by chronic inflammation of the colon and rectum as a result of an exaggerated T-cell response.	15973119
Interstitial inflammation	Altered Intercellular Communication	Kidney biopsy was performed in 3 patients and showed findings consistent with mild interstitial inflammation in 1 patient, and normal renal tissue in 2.	15973524
Vasculitis, Inflammation, Vasculitis, CTCAE, Immune System Diseases	Altered Intercellular Communication	Vasculitis or angiitis is the term used to define the inflammation of the vessels, either blood or lymphatic, which causes may be primary related to immunological disorders, or secondary, with great variety of causal factors.	15973640
Neuropathy	Altered Intercellular Communication	This finding justifies further research on nerve function and neurotransmitters in hemodialysis patients and the introduction of new drugs targeting neuropathy.	15975150
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation, a risk factor for cardiovascular disease, is associated with low plasma levels of antioxidant vitamins.	15975160
Inflammation, Dysplasia	Altered Intercellular Communication	Although amyloidomas in other organ sites may be reflective of a localized or more generalized plasma cell dyscrasia, in the context of its presentation in the lung the presumptive basis has long been held to be one of chronic inflammation.	15975406
HD Term Type, Inflammation	Altered Intercellular Communication	In the attempt to elucidate the mechanisms underlying the coagulation-associated inflammation in HD, 10 HD patients were randomized to be treated subsequently with a cellulose acetate membrane (CA) and Ethylen-vinyl-alcohol (EVAL), a synthetic membrane that has been shown to reduce FXa generation.	15976001
Inflammation, Myocardium	Altered Intercellular Communication	Preoperative C-reactive protein (CRP) and perioperative neutrophil myeloperoxidase (MPO) were also monitored for inflammation, and troponin I was assayed for perioperative cardiac muscle damage.	15976199
Inflammation, Postoperative Period	Altered Intercellular Communication	In this pilot study of cardiac surgery/CPB patients, perioperative upregulation of the monocyte adhesion receptor, CD11b, and higher circulating monocyte and PMN numbers were associated with postoperative AF, suggesting that the induction of cellular inflammation during cardiac surgery/CPB may contribute to this pathophysiology.	15976199
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Inflammation has been linked with atherosclerotic disease development and instability.	15976789
Communicable Diseases, Acute Coronary Syndrome, Inflammation	Altered Intercellular Communication	Contributors to systemic inflammation, such as subclinical infection, may trigger acute coronary syndromes (ACSs).	15976789
Communicable Diseases, Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Underlying infection may precipitate ACS via activation of systemic inflammation.	15976789
Inflammation, Mirizzi Syndrome, Cholelithiasis, Biliary calculi	Altered Intercellular Communication	Mirizzi syndrome is a rare complication of prolonged cholelithiasis, characterized by narrowing of the common hepatic duct due to mechanical compression and/or inflammation due to biliary calculus impacted in the infundibula of the gallbladder or in the cystic duct.	15976905
ACSM3 gene, Inflammation	Altered Intercellular Communication	Reactive oxygen-mediated oxidative damage may play an important role in inflammation after SAH.	15978186
Pain Distress Question, Inflammation, Edema	Altered Intercellular Communication	Adverse effects (AEs) at the injection site (pain, edema, wheal, or inflammation) were monitored for up to 24 hours after surgery.	15978307
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Chronic inflammation is known to play an important role in the heterogeneous pathogenesis of Alzheimer's disease (AD).	15979880
Inflammation, Sarcopenia	Altered Intercellular Communication	It is assumed that low-grade inflammation, characterized by increased circulating IL-6 and TNF-alpha, is related to the development of sarcopenia.	15980654
Inflammation, Neoplasms	Altered Intercellular Communication	Cyclooxygenase-2 (COX-2) is a key modulatory molecule in inflammation and neoplasia.	15980665
Multiple Organ Failure, Acute inflammation	Altered Intercellular Communication	When postoperative inflammation is intense and persists for a long time, postoperative complications may occur, sometimes developing into multiple organ failure.	15981043
Acute myocardial infarction, Myocarditis, Arteritis	Altered Intercellular Communication	TH1/TH2 functional imbalance after acute myocardial infarction: coronary arterial inflammation or myocardial inflammation.	15981090
Inflammation, Myocarditis	Altered Intercellular Communication	There are two different inflammatory processes in patients with AMI: the coronary arterial inflammation that leads to the pathogenesis of AMI and the myocardial inflammation after AMI that leads to ventricular remodeling, which are positively and negatively regulated by Th1 and Th2 lymphocytes, respectively.	15981090
Myocarditis, Arteritis	Altered Intercellular Communication	Th1/Th2 functional imbalance exists in both coronary arterial inflammation and myocardial inflammation processes.	15981090
Neoplastic, Gallbladder Carcinoma	Altered Intercellular Communication	Environmental factors or hormonal changes during aging process may lead to stimulate/promote the genetically altered latent cells to form neoplastic lesions and can act as one of the etiological factors responsible for higher incidence of gall bladder carcinoma in the population of Indo-Gangetic basin.	15981203
Inflammation, Nephrotic Syndrome	Altered Intercellular Communication	Resection of the mass resulted in regression of the signs of inflammation, a negative FDG-PET and complete remission of the nephrotic syndrome.	15981701
Tissue damage, Inflammation	Altered Intercellular Communication	Determining serum CRP on a regular basis may be helpful to detect early signs of tissue damage or asymptomatic inflammation.	15981774
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.	15982504
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation and oxidative stress have been recently implicated in the pathophysiology of atrial fibrillation (AF).	15982504
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Lipoprotein associated phospholipase A2 (Lp-PLA2), a biomarker of oxidation and inflammation, has been associated with increased coronary heart disease (CHD) risk.	15982658
Icterus, Inflammation, Cholestasis	Altered Intercellular Communication	We describe the case of a 42-year-old female Caucasian patient suffering from painless jaundice and showing elevated liver, cholestasis and inflammation laboratory findings 7 days after returning from Tanzania.	15983754
Airway structure, Bronchial Hyperreactivity	Altered Intercellular Communication	Bronchial hyperresponsiveness to adenosine monophosphate, an indirect measure of airway inflammation, is a sensitive marker of inhaled corticosteroid efficacy.	15984601
Inflammation, Fibrosis Assessment, Intussusception	Altered Intercellular Communication	In patients with RI and SRUS, rectal wall inflammation and fibrosis, perhaps arising secondary to the intussusception, may explain the physiological changes observed.	15984985
Inflammation, Atrial Fibrillation by ECG Finding, Cardiac Arrhythmia	Altered Intercellular Communication	C-reactive protein and atrial fibrillation: "evidence for the presence of inflammation in the perpetuation of the arrhythmia".	15985301
Inflammation, Cardiac Arrhythmia	Altered Intercellular Communication	Systemic and/or local inflammation could be involved in the process of thrombogenesis and contribute to the perpetuation of the arrhythmia.	15985301
Inflammation	Altered Intercellular Communication	The purpose of the study was to evaluate the role of inflammation and its relation to thrombogenesis and cardiac rhythm in AF.	15985301
Inflammation	Altered Intercellular Communication	There is evidence for the presence of inflammation in patients with non-valvular AF, which is not related to activation of the coagulation cascade.	15985301
Inflammation	Altered Intercellular Communication	The persistence of inflammation is associated with chronic AF at 1-year follow up.	15985301
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Involvement of inflammation, degradation, and apoptosis in a mouse model of glaucoma.	15985430
Glaucoma, Open-Angle	Altered Intercellular Communication	This increase precedes the onset of clinical evidence of pigmentary glaucoma, implying a pathogenic role of inflammation/immunity in this disease.	15985430
Inflammation, Spanish Language	Altered Intercellular Communication	Inflammation in SpA is characterized by increased TLR-2 and TLR-4 expression, which is sharply reduced by TNFalpha blockade.	15986373
Inflammation	Altered Intercellular Communication	A monoclonal antibody against kininogen reduces inflammation in the HLA-B27 transgenic rat.	15987478
Arthritis, Joint swelling, Gastrointestinal inflammation, Erythema	Altered Intercellular Communication	Stool character as a measure of intestinal inflammation, and the rear limbs for clinical signs of arthritis (tarsal joint swelling and erythema) were scored daily.	15987478
Colitis, Cartilage damage, Synovitis	Altered Intercellular Communication	The animals were killed and the histology sections were assigned a numerical score for colonic inflammation, synovitis, and cartilage damage.	15987478
Refractory anemias, Arthritis, Inflammatory disorder	Altered Intercellular Communication	Our aim was to analyse to what extent sRAGE is present in patients with chronic joint inflammation (RA) as compared with patients with non-inflammatory joint disease and with healthy subjects, and to assess whether there is an association between sRAGE levels and disease characteristics.	15987483
Refractory anemias, Inflammation	Altered Intercellular Communication	Interestingly, a significantly higher sRAGE level was found in synovial fluid of RA patients treated with methotrexate as compared with patients without disease-modifying anti-rheumatic treatment.We conclude that a decreased level of sRAGE in patients with RA might increase the propensity towards inflammation, whereas treatment with methotrexate counteracts this feature.	15987483
Optic Nerve Neoplasms, Inflammation	Altered Intercellular Communication	Differentiating between optic nerve neoplasm and inflammation may be difficult.	15987555
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Association between carotid haemodynamics and inflammation in patients with essential hypertension.	15988541
Inflammation, Hypertensive (finding), Atherosclerosis	Altered Intercellular Communication	These results suggested that carotid haemodynamic parameters such as PI and RI are associated with atherosclerosis and inflammation in hypertensive patients.	15988541
Unique Identifier, Cystitis	Altered Intercellular Communication	UI in many cases is of stress type, but in urinary inflammation a mixed type occurs 1.8 times more frequently.	15989017
Inflammation, Tachyarrhythmia, Critical Illness	Altered Intercellular Communication	Dynamics of inflammation parameters prior to tachyarrhythmias in critically ill patients.	15989113
Inflammation, Tachyarrhythmia	Altered Intercellular Communication	We evaluated the course of inflammation parameters over 48 hours before the occurrence of tachyarrhythmias.	15989113
Inflammation, Tachyarrhythmia, Cardiac Arrhythmia	Altered Intercellular Communication	The body temperature on the day of arrhythmia was 37.4 +/- 1 degrees C. Overall, there was no statistically significant change in any inflammation parameter within 48 hours prior to tachyarrhythmias (C-reactive protein: 17.4 +/- 12 [-48 h], 16.2 +/- 11 [-24 h], 15.2 +/- 12 [0 h] mg/dl, p = 0.2).	15989113
Inflammation, Critical Illness	Altered Intercellular Communication	In this group of critically ill patients inflammation parameters did not change significantly during the 48 hours prior to the arrhythmic event.	15989113
Communicable Diseases, Inflammation	Altered Intercellular Communication	The inflammation, most often caused by alpha-hemolytic streptococci, is most frequently expressed in patients who are more susceptible to infection.	15989117
Inflammation, Anemia, Cirrhotic, Liver Cirrhosis	Altered Intercellular Communication	Our study show that chronic anaemia, in liver cirrhosis, is associated to a greater increase of circulating adhesion molecules and suggests that inflammation may contribute to persistence of anaemic state, worsening the outcome of cirrhotic patients.	15990708
Hemorrhage, Vulva, Vaginal lesion, Endocrine System Diseases	Altered Intercellular Communication	Bleeding in such patients could be caused by local causes such as vulvar or vaginal lesions, or it could be from the endometrium, which is usually a sign of systemic hormonal disturbance [1].	15990731
Inflammation, Acute inflammation, Myocardial, Coronary Artery Disease	Altered Intercellular Communication	An acute inflammatory reaction induced by myocardial damage is superimposed on a chronic inflammation in unstable coronary artery disease.	15990743
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Inflammation plays an important role in unstable coronary artery disease (CAD).	15990743
Myocardial	Altered Intercellular Communication	An early acute inflammatory reaction induced by myocardial damage seems to be superimposed on a chronic inflammatory condition, both of which might influence long-term outcome in unstable CAD.	15990743
Gastritis, Malignant Neoplasms	Altered Intercellular Communication	FT-IR spectroscopy can distinguish gastric inflammation from malignancy.	15991279
Inflammation, Asthma	Altered Intercellular Communication	How do inflammation and remodelling of airways vary with age and with duration and severity of asthma?	15992314
Airway structure	Altered Intercellular Communication	How do we interpret inflammatory changes in the light of age-related airway inflammation?	15992318
Airway structure, Asthma, Atopy	Altered Intercellular Communication	WHAT WE NEED TO KNOW: What changes occur in atopic and non-atopic airway inflammation in asthma with increasing age?	15992320
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	WHAT WE NEED TO DO: Evaluate new diagnostic tools (eg, indirect markers of inflammation) for asthma and COPD.	15992321
Rupture, Heat-Shock Proteins 70, atherosclerotic, Inflammation	Altered Intercellular Communication	Abnormal increments of HSP70 in atherosclerotic plaques might lead to plaque instability and rupture caused by chronic inflammation, which up-regulates the expression of pro-inflammatory cytokines (IL-6 and TNF-alpha) in human monocytes.	15992611
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Routine evaluation using light microscopy to investigate for inflammation, fibrosis, and mast cell count was done.	15992868
Inflammation, Fibrosis Assessment, Deterioration	Altered Intercellular Communication	However, the degree of inflammation and the severity of fibrosis did not affect UUT deterioration.	15992868
Inflammation	Altered Intercellular Communication	TRACP 5a may be a macrophage product of inflammation.	15993395
Inflammation, Chronic disease	Altered Intercellular Communication	In chronic diseases, increased TRACP 5a may represent pathological processes of inflammation unrelated to bone metabolism.	15993395
Inflammation	Altered Intercellular Communication	Sex differences in the relation of body composition to markers of inflammation.	15993885
Inflammation, Obesity	Altered Intercellular Communication	It has been suggested that low-grade systemic inflammation is associated with obesity and that this association might be modified by sex.	15993885
Inflammation, Obesity	Altered Intercellular Communication	Adiposity is strongly associated with low-grade systemic inflammation in men and in women but the association is considerably stronger in women, especially for CRP.	15993885
Inflammation, Weight decreased	Altered Intercellular Communication	Thus, weight reduction as a means to prevent a state of subclinical inflammation might be particularly effective in women.	15993885
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Measurements of nitric oxide at multiple expired flows may be useful in monitoring inflammation and progression of chronic obstructive pulmonary disease, and the response to anti-inflammatory treatment.	15994389
Inflammation, Fibrosis Assessment, Autoimmune Chronic Hepatitis	Altered Intercellular Communication	Histology of a liver biopsy showed marked bridging liver fibrosis and a chronic inflammation, compatible with autoimmune hepatitis.	15996042
Inflammation	Altered Intercellular Communication	This is compatible with the hypothesis that inflammation contributes to the development of cardiovascular events.	15996054
Inflammation	Altered Intercellular Communication	Pulmonary surfactant components may mediate response to inhaled carcinogenic substances and/or play a role in lung function and inflammation.	15996209
Primary Lesion, Primary hypogonadism	Altered Intercellular Communication	Baseline hormonal blood tests indicated a primary gonadal lesion (hypergonadotropic hypogonadism).	15996342
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Cognitive and neuropsychiatric (BPSD) symptoms seen in Alzheimer's disease (AD) probably result from differential neurotransmitter alterations.	15996794
Atherosclerosis	Altered Intercellular Communication	These data support relationship between sex hormones and plasma lipids and suggest that a low testosterone concentration in aging males may be important in the pathogenesis of atherosclerosis.	15997636
Inflammation, Hematoma, Incontinence, Flu-Like Syndrome, CTCAE, External Canal, Epididymitis	Altered Intercellular Communication	In CAF: mild incontinence of the flatus and faeces (9% and 5% of sessions), haematoma (5%), flu-like syndrome (3%), inflammation of external anal varices (2%), epididymitis (1%).	15997637
Intravascular Route of Drug Administration, Inflammation	Altered Intercellular Communication	Increased plasma arginase activity was correlated with increased intravascular hemolytic rate and, to a lesser extent, with markers of inflammation and soluble adhesion molecule levels.	15998894
Tolosa-Hunt Syndrome, Inflammation	Altered Intercellular Communication	Tolosa-Hunt syndrome is caused by an unspecific inflammation in the cavernous sinus or superior orbital fissure.	15999327
Inflammation	Altered Intercellular Communication	Idiopathic hypertrophic cranial pachymeningitis (IHCP) is a rare and little known form of chronic inflammation of the dura mater, the pathogenesis of which remains unclear.	15999328
Inflammation, Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	The extracellular matrix (ECM) molecule osteopontin is implicated in many pathologic processes, including inflammation, cell proliferation, ECM invasion, tumor progression, and metastasis.	16000556
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	A common variant in the glutathione S transferase gene is associated with elevated markers of inflammation and lipid peroxidation in subjects with diabetes mellitus.	16002077
Inflammation	Altered Intercellular Communication	This study demonstrates an association between the GSTT1-1 variant and markers of inflammation and lipid peroxidation.	16002077
Inflammation, Lipolysis, Obesity	Altered Intercellular Communication	In addition waist circumference, HOMA(IR) and FFA levels are associated with CRP levels, suggesting potential roles of obesity, insulin resistance and lipolysis in the development of the subclinical inflammation associated with the MS.	16002176
Airway structure, RETINOSCHISIS 1, X-LINKED, JUVENILE	Altered Intercellular Communication	To characterize the airway inflammation associated with this condition, 20 children [7.4 (0.9) yr old] with "difficult to treat" RS and a positive 24-h oesophageal pH monitoring (pHm) were studied and bronchoalveolar lavage (BAL) performed.	16002270
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Weight decreased	Altered Intercellular Communication	Chronic and systemic inflammation, a potential cause of body weight loss in patients with chronic obstructive pulmonary disease (COPD), may be associated with the proinflammatory properties of secretory phospholipases A2 (sPLA2s), especially the group II subfamily sPLA2s.	16002569
Inflammation, Immediate hypersensitivity, Dermatitis, Atopic	Altered Intercellular Communication	Skin inflammation in atopic dermatitis starts with Th2 and IgE-mediated responses against exogenous allergens and, for unknown reasons, resembles features of a Th1-driven reaction in the chronic stages.	16002733
Dermatitis, Atopy	Altered Intercellular Communication	It may thus contribute to chronic skin inflammation in atopic as well as in nonatopic persons.	16002733
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Diet-quality scores and plasma concentrations of markers of inflammation and endothelial dysfunction.	16002815
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	We assessed the association between several diet-quality scores and plasma concentrations of markers of inflammation and endothelial dysfunction.	16002815
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	C-reactive protein concentrations were 30% (P < 0.05) and 24% (P < 0.05) lower in the top than in the bottom quintile of the AHEI and of the aMED, respectively Higher AHEI and aMED scores were associated with lower concentrations of biomarkers of inflammation and endothelial dysfunction and therefore may be useful as guidelines for reducing the risk of diseases involving such biological pathways.	16002815
vascular inflammations, Thrombosis	Altered Intercellular Communication	Recent data suggest that the pathogenesis of vascular inflammation and thrombosis involves CD40 ligand (CD40L), which is mostly derived from platelets.	16002913
Sepsis, Traumatic injury	Altered Intercellular Communication	In other acute inflammatory conditions, such as sepsis, increased coagulation activation in the microcirculation may be a cause of organ injury.	16002940
Inflammation, Herpes zoster disease, Herpes	Altered Intercellular Communication	The pathogenesis of segmental zoster paresis is inflammation caused by the spread of the herpes virus.	16003688
Inflammation, Fever, CTCAE	Altered Intercellular Communication	The yellow fever vaccine is a known stimulus of systemic inflammation in the body.	16004173
Inflammation, Electrocardiogram: myocardial infarction (finding), Cardiovascular system	Altered Intercellular Communication	We investigated in a median follow up of 3.9 years the association of HDL, apolipoprotein A-I (apoA-I), LDL, apolipoprotein B (apoB), and triglycerides with the incidence of a combined endpoint (myocardial infarction and cardiovascular death) and their relation to markers of inflammation in 1298 patients with angiographically documented CAD.	16004894
Anxiety, CTCAE 3.0, Inflammation	Altered Intercellular Communication	Anxiety in relation to inflammation and coagulation markers, among healthy adults: the ATTICA study.	16005881
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The aim of this work is to examine the association of the anxious state with inflammation and coagulation factors, in persons free of cardiovascular disease.	16005881
Anxiety, CTCAE 3.0, Inflammation	Altered Intercellular Communication	This study revealed that anxiety was associated with inflammation and coagulation markers in cardiovascular disease-free people.	16005881
Airway structure, Lung diseases	Altered Intercellular Communication	Since lung diseases are associated with airway inflammation and oxidative stress, quantification of 3-NT in exhaled breath condensate (EBC) may provide a non-invasive means for monitoring ongoing inflammatory processes.	16006156
Inflammation, Homocysteinemia	Altered Intercellular Communication	Levels of plasma ICAM-1 and S-AA were increased in patients with high plasma tHcy, suggesting an association between homocysteinemia and low-grade inflammation.	16006259
Inflammation, Neoplasms	Altered Intercellular Communication	In nine cases, there was abundant inflammation composed of neutrophils concentrating around the tumor cells, both intraepithelial ('cannibalism') and stromal.	16007065
Inflammation, Hyperplastic Polyp, Calcinosis	Altered Intercellular Communication	AS Calcified nodes present higher concentration of CP and MP suggesting that these bacteria may be associated with the development of calcification and inflammation.	16007307
Inflammation	Altered Intercellular Communication	Epstein-Barr virus infection, together with long-standing inflammation, which causes GCP, may facilitate the development of de novo GRC.	16007390
Inflammation, Gastritis	Altered Intercellular Communication	Furthermore, the histological inflammation and activity scores of H. pylori-positive patients were higher than those of H. pylori-negative patients, without regard to the endoscopic grade of gastritis.	16007389
Inflammation, Carcinoma, Neoplasms, Fibrosis Assessment, Peripheral Nervous System Neoplasms	Altered Intercellular Communication	Twelve enhanced regions (9 peripheral tumor region and 3 entire tumor regions) detected by contrast-enhanced harmonic gray-scale sonography showed: (1) mild fibrosis with inflammation, in 10 regions (83%); (2) the presence of both carcinoma cells and residual acinar cells in 8 (67%); and (3) presence of relatively large arteries in 2 (17%).	16007398
Hypernatremia, Inflammation, Malnutrition	Altered Intercellular Communication	Malnourished patients by the end of the study had a significantly higher incidence of new comorbidities, more inflammation, and a higher incidence of fluid overload.	16007559
Weight Gain, Inflammation, Primary malignant neoplasm, HIV Wasting Syndrome	Altered Intercellular Communication	Megestrol acetate, 800 mg/day, has been shown to increase appetite and food intake and to mitigate inflammation in cachectic AIDS and cancer patients, leading to weight gain, but it is also associated with side effects at this dose.	16007564
Inflammation, Anorexia	Altered Intercellular Communication	Megestrol acetate oral solution in half of its conventional dose is safe and improves the nutritional state, inflammation, and anorexia in maintenance dialysis patients.	16007564
Inflammation	Altered Intercellular Communication	A pleural biopsy immediately preceding the FNA was interpreted as chronic inflammation.	16007670
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Airway inflammation is the main pathophysiological feature of patients with chronic obstructive pulmonary disease (COPD).	16007706
Communicable Diseases, Inflammation	Altered Intercellular Communication	Classical markers of infection cannot differentiate reliably between inflammation and infection after neurosurgery.	16008624
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide (eNO) may represent a useful noninvasive marker of airway inflammation, but data on the reference population values in schoolchildren are limited.	16008675
Chronic cough, Neurogenic Inflammation	Altered Intercellular Communication	Neurogenic inflammation is implicated in the pathogenesis of chronic cough in individuals with normal chest radiography, but the role of NTs in this condition is unknown.	16008683
Airway structure, Coughing	Altered Intercellular Communication	This implies that NTs do not have a central role in perpetuating airway inflammation in chronic persistent cough.	16008683
Inflammation, Uveitis	Altered Intercellular Communication	All of the 34 patients who had a uveitis history over 40 days showed a recurrent inflammation.	16008911
Inflammation, Uveitis	Altered Intercellular Communication	However, none of them showed a bilateral inflammation at the onset of uveitis.	16008911
Intraocular inflammation	Altered Intercellular Communication	Further long-term studies are warranted to determine the safety and efficacy of infliximab in treating intraocular inflammation.	16009830
Inflammation, Behcet Syndrome, Edema, Traumatic injury	Altered Intercellular Communication	The patient had undiagnosed Behcet's disease (BD) and had experienced multiple episodes of pathergy: hyper-responsiveness of the skin to local trauma, resulting in inflammation and edema.	16010282
Myelitis, Traumatic injury	Altered Intercellular Communication	Since the spinal cord inflammation developed after and immediately adjacent to local spinal trauma, we suggest that the TM in this patient was related to BD and was a pathergy response in the spinal cord.	16010282
Granuloma, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Most of the cases (80%) presented a chronic non-caseating granulomatous inflammation, and in two cases predominated foamy macrophages, full of bacteria, and no granuloma formation.	16011609
Pneumonitis	Altered Intercellular Communication	Patients with advanced TB and lung inflammation had an increased number of both PPD-specific IFN-gamma and IL-5 spots in BAL as compared to that in peripheral blood, but the IFN-gamma/IL-5 ratio was about two-fold lower.	16013770
Inflammation	Altered Intercellular Communication	Adhesion molecules, such as P-selectin, play a pivotal role in leukocyte adhesion to the endothelium during inflammation.	16014051
Refractory anemias, Inflammation, Sensorineural Hearing Loss (disorder), Tissue injury	Altered Intercellular Communication	We demonstrated that there is increased SNHL in patients with RA, which may result from systemic inflammation and tissue injury, and increased latent-type CHL caused by stiffness of the middle ear system whose mechanisms are not yet clear.	16015180
Inflammation, Fibrosis Assessment, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	In perimyocarditis., it is useful to check the presence of delayed contrast enhancement to confirm the presence of the lesion and to evaluate the severity of inflammation in the acute stage as well as to determine the extent of fibrosis in the pericardium and myocardium in the chronic stage.	16015449
Inflammation, Postoperative Complications	Altered Intercellular Communication	Two early postoperative complications were also noted a general disuric complication and purulent wound inflammation.	16018384
Inflammation, Brain Injuries, Atherosclerosis, Cerebrovascular accident	Altered Intercellular Communication	Recent literature has demonstrated that inflammation contributes to all phases of atherosclerosis and brain damage caused by stroke.	16018791
Cerebrovascular Disorders, Inflammation, Cerebrovascular accident	Altered Intercellular Communication	In acute phase of cerebrovascular diseases biochemical markers of inflammation, such as C-reactive protein (CRP), could represent an indicator of severity of stroke, but few studies have verified this hypothesis, especially in very old patients.	16018791
Prostate carcinoma, Disseminated Intravascular Coagulation	Altered Intercellular Communication	This report suggests that release of procoagulant material from prostatic carcinoma may be so rapid following hormonal management that consumptive coagulopathy with fibrinolysis can follow.	16019449
Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation was classified according to vitreous examination records as high (2+ cells), low (1/2+ to 1+ cells), or inactive (0 cells).	16019682
Intraocular inflammation	Altered Intercellular Communication	Two patients with high intraocular inflammation had a favorable visual outcome with CST alone.	16019682
Inflammation	Altered Intercellular Communication	Two patients with no intraocular inflammation had unfavorable visual outcome with CST alone (no PDT/TTT available).	16019682
Cessation of life, Inflammation, Depression, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	Seven factors, age > 70 years, male sex, diabetes, previous MI, ST depression, and increased concentrations of troponins and markers of inflammation (interleukin 6 or C reactive protein), were associated with an independent increased risk for death or death/MI.	16020594
Inflammation, Glucose Intolerance (disease), Obesity	Altered Intercellular Communication	These results suggest a possible role of subclinical inflammation in insulin resistance and glucose intolerance in Japanese, but it only partly explains the link between obesity and impaired glucose homeostasis.	16020877
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Biological evidence supports a role of aromatase and butyrilcholinesterase (BCHE) enzymes in the disruption of the cholinergic neurotransmission observed in Alzheimer's disease (AD).	16020944
Inflammation, Dental Plaque	Altered Intercellular Communication	C-reactive protein is an excellent marker for plaque instability or poststent inflammatory status, and its source might be the inflammation site of the plaque or the coronary arterial wall injured by stenting.	16022949
Carcinogenesis	Altered Intercellular Communication	Accumulation of 8-nitroguanine in the liver of patients with chronic hepatitis C. Nucleic acid damage by reactive nitrogen and oxygen species may contribute to inflammation-related carcinogenesis.	16023246
Liver carcinoma	Altered Intercellular Communication	8-Nitroguanine is a useful biomarker to evaluate the severity of HCV-induced chronic inflammation in relation to hepatocellular carcinoma.	16023246
Inflammation, AKAP4 protein, human	Altered Intercellular Communication	The leukocyte count (mean +/- S.E., NI: 7400 +/- 528, LI: 7686 +/- 433, HI: 10952 +/- 691/mm(3), p < 0.001), uric acid (NI: 5.3 +/- 0.24, LI: 7.6 +/- 0.4, HI: 8.9 +/- 0.36 mg/dl, p < 0.001), NO(2) (NI: 6.5 +/- 1.2, LI: 11.1 +/- 2.9, HI: 35.6 +/- 5.1 microg/ml, p < 0.001) and the 8-NO(2)-G (NI: 0.08 +/- 0.03; LI: 0.34 +/- 0.13; HI: 0.59 +/- 0.09 ng/microg DNA, p = 0.002) were significantly increased by inflammation.	16023632
Inflammation	Altered Intercellular Communication	Gouty inflammation induces DNA damage by increasing 8-NO(2)-G through endogenous NO and ROS formation.	16023632
Inflammatory abnormality of the eye	Altered Intercellular Communication	Competing levels of cytokines, either locally within the eye or systemically, may influence the eventual outcome of ocular inflammation.	16024856
Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	There were no differences in conventional risk factors, but markers for inflammation were significantly higher in patients with carotid atherosclerosis than in those with isolated MCA atherosclerosis (p < 0.01 for both).	16024892
Inflammation, Osteoradionecrosis, Nasopharyngeal carcinoma	Altered Intercellular Communication	A false-positive F-18 FDG PET scan caused by osteoradionecrosis and inflammation in patients with nasopharyngeal carcinoma (NPC) has been reported.	16024955
Inflammation, Sensitization (observable entity)	Altered Intercellular Communication	However, an excessive regional inflammation, sensitization of primary somatosensory afferents, and sensitization of spinal neurons are considered to have a role in the pathogenesis of RSD.	16025330
Inflammation, Hyperlipidemia	Altered Intercellular Communication	These results suggest that atorvastatin has beneficial effects on inflammation, oxidative stress, and the lipid profile in patients with hyperlipidemia.	16025360
Stomatitis, TNM Staging System, Stomach Carcinoma	Altered Intercellular Communication	Although no correlation of cathepsin X expression and TNM stage was found, our study demonstrates that cathepsin X plays a role not only in the chronic inflammation of gastric mucosa but also in the tumourigenesis of gastric cancer.	16025436
Osteoporosis, Erectile dysfunction	Altered Intercellular Communication	The frequencies of osteoporosis and erectile dysfunction increased with age, but the association of these conditions seems to be independent of each other and hormonal changes appear not to be the major determinants for both conditions in elderly men.	16025856
Inflammation, Hemorrhage, Perforation (observation), Diverticulosis, Impaction, Calculi, Intestinal Obstruction	Altered Intercellular Communication	The complications from the small intestine diverticulum included inflammation, bleeding, stone, perforation and bowel obstruction which arised from the stagnation, impaction, and friction of the contents in the diverticulum or from adhesion zone of long diveritculum.	16027091
Inflammation, Airway Obstruction, Hypertrophy	Altered Intercellular Communication	Acute inflammation and hypertrophy of lingual tonsil can cause life-threatening airway obstruction.	16027489
Fatty Liver, Inflammation, Liver Cirrhosis	Altered Intercellular Communication	The objective of this study was to investigate whether histological characteristics in patients with fatty liver without inflammation could predict mortality or development of cirrhosis.	16028442
Fatty Liver, Inflammation	Altered Intercellular Communication	A total of 417 patients had a liver biopsy performed, which showed fatty liver without inflammation.	16028442
Inflammation, Non-alcoholic Fatty Liver Disease, Mortality, Premature	Altered Intercellular Communication	In patients with non-alcoholic fatty liver without inflammation, patients at risk for premature death cannot be identified by histological characteristics in the index liver biopsy.	16028442
Inflammation, Rosacea	Altered Intercellular Communication	It is commonly the result of dermal inflammation arising from either a facial surgical procedure, such as laser resurfacing, dermabrasion, or a face peel, or from an underlying dermatologic condition, such as rosacea.	16029682
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The reduced risk of colorectal cancer associated with cyclooxygenase enzyme inhibitors, such as aspirin and other nonsteroidal anti-inflammatory drugs, strongly suggests that chronic inflammation is a key mediator in the development of colorectal cancer.	16030091
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Obesity and type 2 diabetes mellitus are associated with increased levels of IL-6, a marker of inflammation.	16030153
Dyspnea, Chest Pain	Altered Intercellular Communication	Because of aggravating dyspnea and chest pain after an acute upper respiratory inflammation, she was transferred to our hospital on an emergency basis on April 14, 2003.	16030478
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation and type 2 diabetes: results from KORA Augsburg.	16032528
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Type 2 diabetes is associated with a systemic low-grade inflammation.	16032528
Airway structure	Altered Intercellular Communication	The relationship of exhaled nitric oxide to airway inflammation and responsiveness in children.	16032938
Respiratory Hypersensitivity	Altered Intercellular Communication	eNO appears to be a useful indicator of atopy and airway inflammation, but in this population it was not closely related to airway hyperresponsiveness.	16032938
Myositis, Orbital Myositis	Altered Intercellular Communication	Systemic muscular inflammation in a patient with recurrent orbital myositis.	16033136
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation has been recently implicated in the pathophysiology of atrial fibrillation (AF).	16033606
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Low triiodothyronine: a new facet of inflammation in end-stage renal disease.	16033857
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Because inflammation influences thyroid function, it was hypothesized that low plasma free triiodothyronine (fT3) in ESRD may be an unsuspected expression of the inflammatory state of these patients.	16033857
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	In patients who had CKD and were studied during intercurrent inflammatory/infectious processes, fT3 was significantly lower (P = 0.008) at the zenith of inflammation than after its resolution.	16033857
Inflammation, Epididymitis	Altered Intercellular Communication	Ulcerations of the ileum and epididymitis were found, and a pathological examination revealed nonspecific inflammation.	16034549
Conjunctivitis	Altered Intercellular Communication	We present this case to remind ophthalmologists of such a rare cause of recalcitrant conjunctival inflammation in immunocompetent patients.	16035573
Inflammation, myocardial injury	Altered Intercellular Communication	Main plasma analyses were: 8-iso-PGF2alpha (oxidative stress), 15-keto-dihydro-PGF2alpha (cyclooxygenase-mediated inflammation); and troponin-T (myocardial injury).	16036341
Inflammation, Thrombosis, Thickened, Cerebral Angiitis, Fibrosis Assessment, Whipple Disease, Infarction	Altered Intercellular Communication	Arterial or arteriolar fibrosis, thrombosis and thickening associated with the inflammation of adjacent brain parenchyma and leptomeninges, and cerebral vasculitis caused by the hematogenous spread of Tropheryma whippelii to the brain may all be important triggers of brain infarction in patients with Whipple's disease.	16036516
Inflammation, physiopathological	Altered Intercellular Communication	AGEs are also known to activate glia, resulting in inflammation and neuronal dysfunction.	16037241
Inflammation, Transitional cell carcinoma of ureter	Altered Intercellular Communication	The preoperative diagnosis of urothelial cancer in patients with staghorn stones is difficult due to the existing stone and inflammation.	16037702
palladium, Cerebrovascular accident	Altered Intercellular Communication	Increased access to appropriate neurological care and subsequent prevention of stroke after a warning transient ischemic attack may also play a role, as may diminished levels of excitotoxic neurotransmitters in PD patients.	16037918
Inflammation, Primary malignant neoplasm, Hyperplasia, Prostatic Diseases	Altered Intercellular Communication	To clarify the pathology of the development of prostatic disorders such as inflammation, cancer, and hyperplasia, we compared histopathological findings of the prostate according to age group.	16037991
Glandular part of prostate, Inflammation, Large prostate	Altered Intercellular Communication	There was an age-dependent trend towards prostate glandular dilation and prostate enlargement with inflammation.	16037991
Hernia of abdominal cavity, Death by strangulation, Inflammation, Intussusception, Neoplasms, Diaphragmatic Hernia, Intestinal Volvulus	Altered Intercellular Communication	The rate of bowel strangulation was much higher in patients with internal herniation, volvulus, intussusception, closed loop, and diaphragmatic hernia than in patients with simple adhesion, bezoar, tumor, and inflammation (48.3% vs 12.2%).	16038373
Inflammation, Chlamydia, Endothelium, Vascular, Arteriopathic disease	Altered Intercellular Communication	Because of its ability to cause chronic vascular endothelial infection and localized inflammation, Chlamydia has been implicated in the development of arterial vascular disease.	16038672
Inflammation	Altered Intercellular Communication	After resolution of the initial inflammation, apoA-I seems to play an important role in endothelial function.	16039285
Restenosis	Altered Intercellular Communication	Inflammation markers can predict restenosis after successful intracoronary stenting.	16040142
Inflammation, Fibrosis Assessment, Cholangitis	Altered Intercellular Communication	Drain decompression of the cleared BD was used in the presence of cholangitis, an edematous ampulla due to instrumentation or stone impaction and technical difficulties from local inflammation and fibrosis.	16041208
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Oxidant stress and increased systemic inflammation may contribute to this endothelial dysfunction.	16041725
Communicable Diseases, Inflammation	Altered Intercellular Communication	Presence of HHV8-DNA in elderly Italians is associated with childhood crowding, low RBCs, and platelets, perhaps indicating roles for early infection and chronic inflammation.	16043440
Rheumatoid Arthritis, Inflammation, Comorbidity	Altered Intercellular Communication	Paradoxical effect of body mass index on survival in rheumatoid arthritis: role of comorbidity and systemic inflammation.	16043681
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	The role of inflammation in patients with coronary artery disease is emerging.	16043684
Sepsis, Inflammation, Acute myocardial infarction, Shock, Cardiogenic	Altered Intercellular Communication	We sought to assess the profile and outcomes of patients with a clinical syndrome of severe systemic inflammation that led to a diagnosis of suspected sepsis in the setting of acute myocardial infarction complicated by cardiogenic shock (CS).	16043684
Sepsis, Inflammation, Fever, CTCAE, Shock, Cardiogenic	Altered Intercellular Communication	Patients enrolled in the randomized SHOCK (SHould we emergently revascularize Occluded Coronaries for cardiogenic shocK) trial (n = 302) were divided into those with clinical signs of severe systemic inflammation (eg, fever [94%] or leukocytosis [72%]) that led to a diagnosis of suspected sepsis (n = 54 [18%]) and those without suspected sepsis (controls; n = 243 [80%]).	16043684
Sepsis, Acute myocardial infarction, Inflammation, Cessation of life	Altered Intercellular Communication	Almost one fifth of patients with acute myocardial infarction complicated by CS showed clinical signs of severe systemic inflammation, and those who were culture-positive for sepsis had twice the risk of death.	16043684
Shock, Inflammation, Communicable Diseases	Altered Intercellular Communication	The observation of lower SVR at the onset of shock in patients who subsequently had culture-positive systemic inflammation suggests that inappropriate vasodilation may play an important role in the pathogenesis and persistence of shock and in the risk of infection.	16043684
Inflammation, Rheumatic Heart Disease	Altered Intercellular Communication	Inflammation and genetics may play a role in the pathogenesis of rheumatic heart disease (RHD).	16043936
Inflammation, Disease remission	Altered Intercellular Communication	In CD patients, moderate-severe clinical activity (OR, 4.5; 95% CI, 1.1-18.3), active disease at colonoscopy (OR, 3.5; 95% CI, 1.4-8.9), and histologically severe inflammation (OR, 10.6; 95% CI; 1.1-104) were all significantly associated with CRP elevation.	16043984
Inflammation, Ulcerative Colitis, Disease remission, Anemia, Hypoalbuminemia	Altered Intercellular Communication	In UC patients, CRP elevation was significantly associated with severe clinical activity, elevation in sedimentation rate, anemia, hypoalbuminemia, and active disease at ileocolonoscopy, but not with histologic inflammation.	16043984
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	CRP elevation in IBD patients is associated with clinical disease activity, endoscopic inflammation, severely active histologic inflammation (in CD patients), and several other biomarkers of inflammation, but not with radiographic activity.	16043984
Intraocular inflammation, Keratitis, Herpetic, Corneal Neovascularization	Altered Intercellular Communication	Specific antibody production in herpes keratitis: intraocular inflammation and corneal neovascularisation as predicting factors.	16044329
Intraocular inflammation, Corneal Neovascularization	Altered Intercellular Communication	Local antibody production was significantly associated with intraocular inflammation (P<0.05), corneal neovascularisation (P<0.05), and positive response to anti-viral treatment (P<0.05).	16044329
Intraocular inflammation, Pathologic Neovascularization, Herpes, Pathology	Altered Intercellular Communication	It might be particularly helpful in patients presenting with intraocular inflammation and neovascularisation since it discriminates between herpes and non-herpes pathologies and may therefore be useful for preventive and therapeutic strategies.	16044329
Inflammation, Hepatitis C, Liver Cirrhosis, FAM126A gene	Altered Intercellular Communication	The inflammation and cirrhosis caused by HCV could be the promoter for development of HCC or HCC could be the consequence of HCV infection independent of the effect of cirrhosis.	16045605
Inflammation	Altered Intercellular Communication	Skin and lymph node biopsies showed granulomatous inflammation and special stains demonstrated long septate hyphae.	16045679
Inflammation, Acute Coronary Syndrome, Acute chest pain	Altered Intercellular Communication	A comparative study of markers of inflammation for the assessment of cardiovascular risk in patients presenting to the emergency department with acute chest pain suggestive of acute coronary syndrome.	16046018
Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	The role of inflammation in the pathogenesis of acute coronary syndrome (ACS) is established.	16046018
Inflammation	Altered Intercellular Communication	Female sex, high-homocysteine, low-grade inflammation, CAD and cerebrovascular event history was found to be associated with both modified WHO and NCEP MS groups in the multivariate analysis.	16046242
Inflammation	Altered Intercellular Communication	Low grade inflammation as assessed by CRP and high-homocysteine level is strongly related to MS.	16046242
Inflammation, Helicobacter pylori, Chlamydia	Altered Intercellular Communication	Detection of Helicobacter pylori and Chlamydia pneumoniae DNA in human coronary arteries and evaluation of the results with serologic evidence of inflammation.	16047055
Inflammation, Atherosclerosis	Altered Intercellular Communication	The increased titers of inflammation markers in DNA positive patients support inflammation in atherosclerosis, however, the results should be reproduced in a larger cohort.	16047055
Necrotizing granulomatous inflammation, Inflammation, Tuberculosis, Ulcer	Altered Intercellular Communication	Histopathologic analysis of an ulcerative finger lesion demonstrated nonnecrotizing granulomas with dense lymphocytic inflammation of the superficial dermis; however, results of acid-fast staining, mycobacterial culture, and polymerase chain reaction for M tuberculosis complex were all negative.	16047872
Inflammation, Acanthosis, Papillomatosis, Hyperkeratosis	Altered Intercellular Communication	The results of cutaneous biopsy specimens typically reveal hyperkeratosis, acanthosis, and mild papillomatosis with minimal inflammation.	16047873
Constipation	Altered Intercellular Communication	The pathophysiology of constipation is not clearly identified as yet, and the interstital cells of Cajal (ICC), known to generate the slow wave activity and to be involved in intestinal neurotransmission and the enteric nervous system (ENS), are suspected to play an important role.	16048580
Granulomatous inflammation, Pericarditis, CTCAE	Altered Intercellular Communication	ADA levels were higher in cases with histological evidence of granulomatous inflammation than in cases with serofibrinous pericarditis.	16049586
Inflammation, Lymphoid hyperplasia	Altered Intercellular Communication	Its purpose is to detect rare diseases that differ from "chronic inflammation" or "lymphatic hyperplasia".	16049685
Inflammation	Altered Intercellular Communication	These results suggest that the interaction between nifedipine and gingival inflammation might play an important role in the pathogenesis of nifedipine-induced gingival overgrowth.	16050491
inflammation or infection	Altered Intercellular Communication	The level of monocyte HLA-DR expression reflects the functional status of monocytes as antigen-presenting cells and granulocyte CD64 expression is also indicative of infectious inflammation.	16050543
Sepsis, Inflammation	Altered Intercellular Communication	In contrast, granulocyte CD64 sharply rises in patients with sepsis and correlates with mediators of systemic inflammation (procalcitonin - PCT), proinflammatory mediators (interleukin-6 - IL-6, lipopolysaccharide binding protein - LBP) and anti-inflammatory cytokines (interleukin-10 - IL10).	16050543
Inflammation, Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	Probiotics may ease symptoms in IBS patients by changing gut microflora, reducing mucosal inflammation and exerting antibacterial effects.	16051399
Inflammation	Altered Intercellular Communication	Spectroscopy pointing to ongoing inflammation, gliosis, and possible membrane turnover was more sensitive than imaging in detecting widespread pathology within the white matter.	16051471
Inflammation, Hemorrhage, Fibrosis Assessment	Altered Intercellular Communication	Microscopic examination revealed mucosal ulceration, mucosal and submucosal haemorrhages, fusion and shortening villi, chronic inflammation, and fibrosis of the submucosa.	16051582
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	We demonstrate that common genetic variants of CRP (3'UTR 1846C/T) and IL-6 (-174G/C) are significantly associated with the risk of stroke after cardiac surgery, suggesting a pivotal role of inflammation in post-cardiac surgery stroke.	16051899
Inflammation	Altered Intercellular Communication	Systemic inflammation after coronary intervention identifies patients at increased risk of subsequent cardiac events.	16052297
Psoriasis, Necrosis	Altered Intercellular Communication	Administration of anti-tumor necrosis factor (anti-TNF) agents is beneficial in a variety of chronic inflammatory conditions, including psoriasis.	16052599
Blood Vessel, Kidney Diseases, Precocious	Altered Intercellular Communication	In precocious stages of renal disease, and as a consequence of the inflammatory condition generated already exists vascular damage.	16053009
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation may be one of the mechanisms for the development and persistence of atrial fibrillation.	16053785
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Increased plasma hsCRP was probably involved in the occurrence of MA, suggesting that inflammation may deteriorate endothelial dysfunction.	16053788
Inflammation, Reperfusion Injury	Altered Intercellular Communication	Global inflammation in response to whole-body ischemia-reperfusion is common after OHCA and may worsen the overall prognosis.	16053954
Neurodegenerative Disorders, Midomafetamine, Inflammation	Altered Intercellular Communication	It has been shown that apo E increased the production of nitric oxide (NO) from human monocyte-derived macrophages (MDM); this effect could represent an important link between tissue redox balance and inflammation, since inflammation and oxidative stress are involved in chronic neurodegenerative disorders.	16054114
Inflammation, Tumor necrosis	Altered Intercellular Communication	Markers of inflammation were soluble tumor necrosis factor-alpha receptors 1 and 2 (sTNF-R1 and sTNF-R2), C-reactive protein (CRP), and interleukin-6 (IL-6).	16055129
Inflammation, Myocardial	Altered Intercellular Communication	The increase in CRP levels during Q-wave MI seems to be linked to the extension of myocardial damage rather than pre-existing inflammation.	16055214
Airway structure, Asthma, MS4A2 wt Allele	Altered Intercellular Communication	The results suggest that atopy related indices and airway inflammation are separate dimensions in the assessment of childhood asthma, and inflammatory markers in peripheral blood and EBC are non-overlapping factors of asthma.	16055623
Airway structure, Asthma	Altered Intercellular Communication	Effector memory T-cells (CD45RO+) may provide pro-inflammatory signals that contribute to the persistent airway inflammation that is characteristic of asthma, and reduced apoptosis of these cells may prolong their effects.	16055874
Airway structure, Asthma	Altered Intercellular Communication	Effector memory T-cells (CD45RO+) may provide pro-inflammatory signals that contribute to the persistent airway inflammation that is characteristic of asthma, and reduced apoptosis of these cells may prolong their effects.	16055874
Inflammation, Dyslipidemias, Hypertension, CTCAE	Altered Intercellular Communication	Hemodialysis (HD) patients often experience cardiovascular events, that might be related to altered calcium-phosphate metabolism, dyslipidemia, and chronic inflammation in addition to hypertension.	16060120
Inflammation	Altered Intercellular Communication	However, the influence of sevelamer on chronic inflammation has not been clarified.	16060120
Inflammation, Hyperparathyroidism, Anemia	Altered Intercellular Communication	The prevalence of insulin resistance and its relationship between anemia, secondary hyperparathyroidism, inflammation, and cardiac parameters in chronic hemodialysis patients.	16060127
Inflammation	Altered Intercellular Communication	Relevance of procalcitonin levels in comparison to other markers of inflammation in hemodialysis patients.	16060132
Inflammation, Granulomatosis with polyangiitis, Infection	Altered Intercellular Communication	These epithelial reactions have also been reported with medications, infections, inflammation, Wegener's granulomatosis, and jejunoileal bypass.	16060139
Inflammation	Altered Intercellular Communication	All patients who underwent complete circumcision and surgical specimens were typed histologically as early, intermediate, or late forms of this disorder or as nonspecific chronic inflammation.	16060864
Inflammation, myocardial injury	Altered Intercellular Communication	Myocardial injury, neurohormonal activation and inflammation after internal atrial defibrillation.	16061126
Inflammation, Erythema	Altered Intercellular Communication	When any degree of erythema or inflammation was seen, the infusion site was changed.	16061456
Calcification of mitral valve, Hyperlipidemia, Inflammation, Osteoporosis	Altered Intercellular Communication	001), osteoporosis (p < 0.03), mitral ring calcification (p = 0.047), dislipidemia (high serum level of total cholesterol, cholesterol of low density lipoproteins, and apoB, atherogenic shift of apoB/apoA-1 ratio, low level of cholesterol of high density lipoproteins (CHDLP)), disbalance between intecellular matrix synthesis and destruction (high concentration of alkaline phosphatase and its bone fraction, and accelerated deoxypyridinoline excretion), inflammation (high concentration of C-reactive protein (CRP), fibrinogen, and interleukin-6 (IL-6)).	16075646
Hyperlipidemia, Inflammation, Calcinosis, Osteoporosis	Altered Intercellular Communication	The factors of AOS were: age (p < 0.001), smoking (p < 0.001), osteoporosis (p = 0.004), AVC (p < 0.001), mitral ring calcinosis (p = 0.033), dislipidemia (high levels of cholesterol of low density and very low density lipoproteins, low concentrations of CHDLP, and apoA-1), degradation of extracellular matrix, and inflammation (high concentrations of CRP, fibrinogen, IL-6, and IL-8).	16075646
Inflammation	Altered Intercellular Communication	The revealed immune status changes imply the role of inflammation in the development and progress of AVS.	16075646
Inflammation, atherosclerotic	Altered Intercellular Communication	Inflammation plays an essential role in the atherosclerotic process.	16076683
Inflammation, Platelet aggregation test result	Altered Intercellular Communication	The objective of the study was to investigate markers of inflammation, platelet activation, and platelet aggregation in a model of caloric deprivation and increased leptin sensitivity.	16076944
Communicable Diseases, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	It is mainly caused by surgical injury, local cancer recurrence, and chronic inflammation or infection.	16077339
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Therefore, this marker of low-grade inflammation may play a major role in the pathogenesis of cardiovascular diseases.	16077717
Inflammation, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Additionally, we found that central obesity and high blood pressure are the most important determinants of the low-grade chronic inflammation present in metabolic syndrome.	16077717
Cholecystitis, Acalculous Cholecystitis	Altered Intercellular Communication	The diagnosis of calculous cholecystitis was confirmed by ultrasonography or histological confirmation of acute or chronic inflammation of the gallbladder.	16078299
Rheumatoid Arthritis, Inflammation, Juvenile rheumatoid arthritis	Altered Intercellular Communication	IGF1 is decreased in rheumatoid arthritis and juvenile idiopathic arthritis because its synthesis is inhibited by inflammation.	16079165
Inflammation, Ischemia, Thrombophilia, Diabetes Mellitus, platelet dysfunction, CLU protein, human, Chronic Kidney Diseases	Altered Intercellular Communication	The high incidence of diabetes, chronic renal disease, platelet dysfunction, hypercoagulability, inflammation and a thrombus-rich environment make a GP IIb-IIIa and DTI combination with tirofiban (Aggrastat Merck and Company, Inc., Whitehouse Station, New Jersey) an attractive anticoagulation strategy in the PPI treatment of critical limb ischemia (CLI).	16079449
Inflammation, Chronic heart failure	Altered Intercellular Communication	Exercise training in chronic heart failure: correlation between reduced local inflammation and improved oxidative capacity in the skeletal muscle.	16079649
Inflammation, Thrombosis	Altered Intercellular Communication	Contrast-enhanced computed tomography of the neck revealed thrombosis in the left internal jugular vein, subclavian vein, and brachiocephalic vein and diffuse soft tissue inflammation around the veins.	16079933
Uterine Cervicitis, Trichomonas Vaginitis, Tuberculosis	Altered Intercellular Communication	The OR of oncogenic HPV were: 1.41 (95% CI = 1.25-1.60) and 1.42 (95% CI = 1.24-1.61) for the participant and her husband having multiple sexual partners, respectively; 1.67 (95% CI = 1.37-2.04), 1.15 (95% CI = 1.04-1.26), and 0.82 (95% CI = 0.72-0.94) for ever (vs. never) diagnosed with tuberculosis, cervical inflammation and vaginal trichomoniasis, respectively; while bathing in a public (v. private) facility had an OR of 1.23 (95% CI =1.11-1.35).	16080192
Inflammation, Coronary heart disease, Vascular System Injuries	Altered Intercellular Communication	The mechanism responsible for the increase of CECs in acute coronary disease may be due to the vessel injury caused by inflammation.	16080813
Inflammation, Heart failure, Congestive heart failure	Altered Intercellular Communication	In patients with severe heart failure (CHF), chronically elevated cytokine levels document a systemic inflammation.	16080978
Chlamydia trachomatis, Prostate carcinoma, prostatitis	Altered Intercellular Communication	Subclinical prostatic inflammation attributable to Chlamydia trachomatis in a patient with prostate cancer.	16082070
Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Chronic inflammation has long been linked to cancers with an infectious etiology.	16082070
Inflammation	Altered Intercellular Communication	MR imaging findings well reflect the basic pathological process of inflammation, and inflammatory adnexal masses are associated with relatively specific appearances in MR images.	16082146
Inflammation	Altered Intercellular Communication	Using a modified Histologic Activity Index (HAI), there was no difference between Group 1 and Group 2 in portal inflammation or periportal injury.	16082284
Inflammation	Altered Intercellular Communication	However, parenchymal (lobular) injury and inflammation was significantly (P<0.0001) greater in Group 1 than Group 2.	16082284
Necrosis with inflammation, Accumulation of copper in liver, Fatty degeneration, Necrosis	Altered Intercellular Communication	Oxidative stress and lipid peroxidation play major roles in the fatty liver accumulation (steatosis) that leads to necro-inflammation and necrosis of hepatic cells.	16082287
Inflammation, Spondylarthritis, Spondylitis	Altered Intercellular Communication	Spondyloarthritis Research Consortium of Canada magnetic resonance imaging index for assessment of spinal inflammation in ankylosing spondylitis.	16082639
Inflammation, Spondylitis, Spondylarthropathies	Altered Intercellular Communication	To develop a feasible magnetic resonance imaging (MRI)-based scoring system for spinal inflammation in patients with spondylarthropathy that requires minimal scan time, does not require contrast enhancement, evaluates the extent of lesions in 3 dimensional planes, and limits the number of vertebral levels that are scored because MRI demonstrates characteristic inflammatory lesions in the spine of patients with ankylosing spondylitis (AS) prior to the development of typical features on plain radiographic.	16082639
Inflammation, Spondylarthritis	Altered Intercellular Communication	The Spondyloarthritis Research Consortium of Canada MRI index is a feasible, reproducible, and responsive index for measuring spinal inflammation in AS.	16082639
Inflammation, Arthritis, Reduced	Altered Intercellular Communication	Decreased pain and synovial inflammation after etanercept therapy in patients with reactive and undifferentiated arthritis: an open-label trial.	16082643
Inflammation, Chronic sinusitis, Craniosynostosis, exacerbation acute	Altered Intercellular Communication	The mechanisms by which eosinophilic inflammation damages the epithelium and contributes to recurrent acute exacerbations in chronic rhinosinusitis (CRS) have not been fully elucidated.	16083791
Myositis	Altered Intercellular Communication	Muscle inflammation was seen in patients with U1-RNP and U3-RNP.	16084222
Inflammation, Hypoxia	Altered Intercellular Communication	In conclusion, the etiopathogenesis of these cells can be partially explained by hypoxia, inflammation, regeneration/repair, and cell turnover alone or, more probably, in combination in the granulation tissue response to injury.	16084451
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	The pathological findings, together with clinical courses of our cases, suggest that inflammation accompanied by autoimmune diseases may play, in part, an important role in the development of MTCs.	16084956
Sepsis, Inflammation, Mycoses, Hypotension, CTCAE	Altered Intercellular Communication	Sepsis is a potentially life-threatening medical condition induced by viral, bacterial or fungal infection, which is characterized by systemic inflammation, hypotension and vasodilation that can lead to cardiovascular collapse.	16085122
Inflammation	Altered Intercellular Communication	FDG concentrates in lesions due to the relatively dense cellularity in regions of inflammation of active atheromas.	16085583
Arterial calcification, atherosclerotic, Neoplasms, Vascular calcification	Altered Intercellular Communication	This investigation examines the geographic relationship of focal vascular (18)F-FDG uptake, as a marker of atherosclerotic inflammation, to arterial calcification detected by contemporaneous CT. We reviewed PET/CT images from 78 patients who were referred for tumor staging for the presence of vascular (18)F-FDG uptake and vascular calcification.	16085583
Inflammation, Calcinosis	Altered Intercellular Communication	Arteries typically displayed a patchwork of normal vessel, focal inflammation, or calcification; inflammation and calcification overlapped in <2% of cases.	16085583
Inflammation, Calcinosis	Altered Intercellular Communication	Arterial inflammation preceded calcification, in terms of mean patient age.	16085583
Inflammation	Altered Intercellular Communication	Coronary inflammation was more prevalent in patients with more cardiovascular risk factors.	16085583
Inflammation	Altered Intercellular Communication	The histological severity of chronic inflammation also negatively influenced the ghrelin mRNA expression (p < 0.001) and peptide production (p < 0.005).	16086706
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	Patterns of inflammation associated with peripheral arterial disease: the InCHIANTI study.	16086930
Inflammation, Restenosis	Altered Intercellular Communication	These findings provide strong support for the role of inflammation in restenosis.	16086941
Inflammation, Toxic effect	Altered Intercellular Communication	Corneal toxicity and inflammation secondary to retained perfluorodecalin.	16086960
Keratopathy, Inflammation	Altered Intercellular Communication	To describe a case with bullous keratopathy and anterior segment inflammation associated with heavy liquids.	16086960
Cerebellar Ataxia	Altered Intercellular Communication	To determine the exact role of GAD-Ab and gamma-aminobutyric acid (GABA)-ergic neurotransmission in the pathogenesis of cerebellar ataxia.	16087772
Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation contributes to low plasma amino acid concentrations in patients with chronic kidney disease.	16087977
Inflammation, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation and malnutrition are common in chronic kidney disease (CKD) patients, and plasma concentrations of free amino acids (AAs) in these patients are often abnormal.	16087977
Inflammation, Malnutrition	Altered Intercellular Communication	The patients with inflammation [C-reactive protein (CRP) concentrations >10 mg/L] or malnutrition had lower AA concentrations than did the patients with no inflammation or malnutrition.	16087977
Inflammation, Malnutrition	Altered Intercellular Communication	The presence of both inflammation and malnutrition was associated with more marked reductions in AA concentrations than was malnutrition alone.	16087977
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Plasma AA concentrations are low in CKD patients with inflammation and are inversely correlated with concentrations of inflammatory markers.	16087977
Inflammation, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	Although inflammation and malnutrition are closely related, CRP concentrations were independently associated with low concentrations of the sums of both nonessential AAs and all AAs, which suggests an independent role of inflammation as a cause of low plasma AA concentrations in CKD patients.	16087977
Inflammation, Abnormal prostate morphology	Altered Intercellular Communication	This relation may be explained by inflammation and hemostatic abnormalities.	16087989
Inflammation, Sarcopenia	Altered Intercellular Communication	Obesity-associated inflammation may play an important role in the age-related process that leads to sarcopenia.	16087989
Inflammation, Sarcopenia, Obesity	Altered Intercellular Communication	The relation of inflammation with sarcopenia was not independent of any of the considered obesity indexes.	16087989
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Interleukin-1 gene cluster polymorphisms are associated with nutritional status and inflammation in patients with end-stage renal disease.	16088107
Cessation of life, Inflammation, Kidney Failure, Chronic, Cachexia	Altered Intercellular Communication	Wasting and inflammation are two common risk factors for death in patients with end-stage renal disease (ESRD).	16088107
Inflammation, Cachexia	Altered Intercellular Communication	Interleukin-1beta (IL-1beta) and its receptor antagonist (IL-1Ra) may play a pivotal role in the pathogenesis of wasting and inflammation.	16088107
Inflammation, Cachexia	Altered Intercellular Communication	Wasting (SGA>1) was present in 31%, whereas inflammation (CRP>/=10 mg/l) was present in 36% of the patients.	16088107
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	The investigated IL-1 gene cluster polymorphisms were associated with nutritional status and inflammation in ESRD patients, but marked differences were found between the genders.	16088107
Kidney Failure, Chronic, Inflammation, Cachexia	Altered Intercellular Communication	These polymorphisms could have prognostic utility for predicting wasting and inflammation in ESRD patients.	16088107
Inflammation	Altered Intercellular Communication	Histologic evaluation of the resected mass showed evidence of acute and chronic inflammation with associated foreign material.	16091543
Inflammation, Hypertrophy	Altered Intercellular Communication	It is characterized by chronic inflammation and obstruction of the lymphatic channels and by hypertrophy of the skin and subcutaneous tissues.	16092000
Inflammation, Muscular Dystrophy, Duchenne	Altered Intercellular Communication	Early onset of inflammation and later involvement of TGFbeta in Duchenne muscular dystrophy.	16093456
Granulomatosis with polyangiitis, Pneumonitis	Altered Intercellular Communication	However, not every ANCA-positive patient with pulmonary inflammation is suffering from Wegener's disease.	16093579
Granulomatous inflammation, Pulmonary hemorrhage, Vasculitis of the skin, Fever, CTCAE	Altered Intercellular Communication	A 25-year-old woman developed fever, granulomatous inflammation of nasal mucosa, pulmonary hemorrhage, suprascleritis, and cutaneous vasculitis.	16093600
Intestinal metaplasia, Gastritis, Gastritis, Atrophic	Altered Intercellular Communication	Patients with positive AHPA had higher scores in gastric atrophy, intestinal metaplasia, and gastric inflammation of antrum than those patients with negative AHPA.	16094716
Inflammation, Angiomyoma, Granulation finding	Altered Intercellular Communication	The first histopathological examination was "angioleiomyoma exulcerans, chronic inflammation and granulation."	16095104
Physical disability, Fibrinoid necrotizing inflammation, Pain Distress Question	Altered Intercellular Communication	[Progressive physical disability, pain and quality of life of patients with rheumatoid inflammation of the joints].	16095151
Inflammation, Hematoma, Necrosis, Communicable Diseases, Hypoxia, Calcinosis	Altered Intercellular Communication	As the mechanisms of delayed signal sequence of hematoma on MRI, we speculate existence of tissue hypoxia associated with infection and paramagnetic effects of free radicals and ions associated with inflammation, necrosis and calcification.	16095211
Neurogenic Inflammation, Nociceptive Pain	Altered Intercellular Communication	Topical capsaicin is well known to reduce nociceptive pain and neurogenic inflammation by depleting substance P. Its fibrinolytic and antithrombotic effects are less well known.	16096187
Psoriatic Juvenile Idiopathic Arthritis, Arthritis, Common Compensatory Fascial Pattern	Altered Intercellular Communication	Antibodies against cyclic citrullinated peptide (CCP) in psoriatic patients with or without joint inflammation.	16096328
Psoriatic Juvenile Idiopathic Arthritis, Arthritis, Refractory anemias	Altered Intercellular Communication	To compare the prevalence of anti-CCP antibodies in psoriatic patients with and without joint inflammation, patients with early RA, and controls.	16096328
Inflammation, Arthritis	Altered Intercellular Communication	STAT1 expression is increased in inflammatory arthritis, suggesting that its pro-apoptotic and anti-inflammatory effects cannot effectively counteract inflammation.	16096332
Inflammation, Edema, Uveitis	Altered Intercellular Communication	Low-dose intraocular triamcinolone injection for intractable macular oedema and inflammation in patients with uveitis.	16096656
Macular Edema, Cystoid, Intraocular inflammation	Altered Intercellular Communication	To evaluate the efficacy and safety of low-dose (2 mg in 0.05 ml) intraocular triamcinolone injection for patients with uveitis-related cystoid macular oedema and/or intractable intraocular inflammation.	16096656
Intraocular inflammation	Altered Intercellular Communication	Intractable intraocular inflammation was eliminated in 4/8 eyes (50%).	16096656
Fibrosis Assessment, Hepatitis B, Intrahepatic Route of Drug Administration	Altered Intercellular Communication	Compared with patients without core promoter mutations, patients with core promoter mutations had more severe intrahepatic inflammation and fibrosis, and more cytoplasmic expression of hepatitis B core antigen (P = 0.028).	16097996
Inflammation, Fibrosis Assessment, Hepatitis B, Intrahepatic Route of Drug Administration	Altered Intercellular Communication	Intrahepatic hepatitis B virus DNA levels correlated with serum hepatitis B virus DNA levels (r = 0.71, P < 0.001) and the percentage of hepatitis B core antigen-positive hepatocytes (r = 0.37, P = 0.047), but had no correlation with serum alanine aminotransferase levels nor the degree of inflammation and fibrosis.	16097996
Inflammation, Fibrosis Assessment, Hepatitis B	Altered Intercellular Communication	Patients with core promoter mutations had more severe inflammation and fibrosis, and more frequent cytoplasmic expression of hepatitis B core antigen.	16097996
Tumor necrosis, Acute Coronary Syndrome, Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) are key mediators of inflammation and their increased plasma levels are associated with acute coronary syndrome (ACS).	16098388
Inflammation, Joints, Refractory anemias, Degenerative polyarthritis, Vasculitis, CTCAE	Altered Intercellular Communication	The lack of a significant difference in CBV over PIP joints between RA and OA patients might be due to some inflammation also occurring in OA rather than to vasculitic processes in RA associated with elevated levels of soluble adhesion molecules.	16098542
Inflammation	Altered Intercellular Communication	the degree of mucosal inflammation, nasal patency, general state of health, condition of the middle ear, auditory function as well as an assessment of complaints by the parents.	16098615
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterised by progressive airflow limitation associated with chronic inflammation.	16099292
Sepsis, Inflammation, Heart failure	Altered Intercellular Communication	MR-proADM measurements may be useful for evaluating patients with sepsis, systemic inflammation, or heart failure.	16099941
methyldopa, Drusen, Inflammation, Monkeys	Altered Intercellular Communication	Monkey drusen both in late and early onset forms of macular degeneration had common components with drusen in human AMD patients, indicating that chronic inflammation mediated by complement activation might also be involved in the formation of drusen in these affected monkeys.	16099945
Inflammation, Hypogonadism	Altered Intercellular Communication	Moreover, to study the relationship of hypogonadism with quadriceps muscle force, 6-min walking distance, and systemic markers of inflammation in the patients.	16100014
Inflammation	Altered Intercellular Communication	These data suggest that systemic inflammation may influence the degree of procedural embolization.	16100016
Pleurisy, effusion	Altered Intercellular Communication	A higher intensity of pleural inflammation in loculated effusions may enhance the release of TNF-alpha, IL-1beta, and TGF-beta1, which may subsequently increase the levels of PAI-1.	16100155
vascular inflammations, Dental Plaque, Calcification of coronary artery	Altered Intercellular Communication	Coronary artery calcification determined by electron beam CT (EBCT) is strongly associated with total plaque burden but is not related to systemic vascular inflammation.	16100172
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	These findings suggested that both calcium deposition and inflammation were involved in endothelial dysfunction.	16100172
Ocular sarcoidosis, Inflammation	Altered Intercellular Communication	Eighteen patients with ocular sarcoidosis and ongoing inflammation in the eyes.	16100213
Inflammation, Observation Method - Coagulation, Coronary heart disease	Altered Intercellular Communication	Indicators of coagulation and inflammation are elevated in patients with coronary heart disease.	16101627
Inflammation, CAV1 gene, Atherosclerosis	Altered Intercellular Communication	We investigated the degree of inflammatory reaction during PCI in CAV compared to patients with native atherosclerosis, and the possible relationship between PCI-induced inflammation and the degree of re-stenosis in these 2 patient groups.	16102437
Inflammation, CAV1 gene	Altered Intercellular Communication	Nevertheless, an inappropriate inflammatory reactivity may predispose to re-stenosis after PCI in both groups of patients, with pre-procedural inflammation being of particular importance in CAV.	16102437
Inflammation	Altered Intercellular Communication	Neointimal inflammation and adventitial angiogenesis correlate with severity of cardiac allograft vasculopathy in pediatric recipients.	16102439
Inflammation, CAV1 gene, Vascular Diseases	Altered Intercellular Communication	Chronic inflammation and angiogenesis have been implicated in the pathogenesis of both cardiac allograft vasculopathy (CAV) and age-related vasculopathy.	16102439
Inflammation	Altered Intercellular Communication	Each case was assigned to either: Group I, no inflammation; Group II, perivascular inflammation; or Group III, perivascular and neointimal inflammation.	16102439
Inflammation, CAV1 gene	Altered Intercellular Communication	CAV was evident in 94% of cases, and inflammation in 61%.	16102439
Inflammation, CAV1 gene	Altered Intercellular Communication	Cases with neointimal inflammation had significantly more severe CAV compared with cases without inflammation (2.7 +/- 0.16 vs 1.9 +/- 0.2, p = 0.002).	16102439
Inflammation, CAV1 gene	Altered Intercellular Communication	MVD was significantly higher in both inflammation groups (Groups II and III) compared with Group I (4.1 +/- 0.5 per HPF and 5.9 +/- 0.5 vs 3.1 +/- 0.7, p = 0.018 and p = 0.002) and correlated with the degree of CAV (p = 0.007).	16102439
Inflammation, CAV1 gene	Altered Intercellular Communication	Our data indicate that CAV is often associated with inflammation and that adventitial angiogenesis correlated with the severity of CAV.	16102439
Left coronary artery structure, Obesity	Altered Intercellular Communication	The reported link between early growth and later obesity may be due partly to hormonal programming, and partly to the contribution of LM to obesity indices based on weight and height.	16103893
Inflammation, Restenosis	Altered Intercellular Communication	In-stent restenosis is a major problem following coronary stent implantation, and inflammation plays an active role.	16104442
Inflammation	Altered Intercellular Communication	Microscopic appearance showed that the tape was intact and no evidence of inflammation or mineralization.	16104566
Parkinson Disease, Chronic infectious disease, Inflammation	Altered Intercellular Communication	Role of chronic infection and inflammation in the gastrointestinal tract in the etiology and pathogenesis of idiopathic parkinsonism.	16104942
Parkinson Disease, Chronic infectious disease, Inflammation	Altered Intercellular Communication	Role of chronic infection and inflammation in the gastrointestinal tract in the etiology and pathogenesis of idiopathic parkinsonism.	16104944
Inflammation	Altered Intercellular Communication	At baseline, smokers showed significantly less gingival inflammation and lower GCF volume compared with non-smokers.	16104962
Inflammation, Hypertrophy	Altered Intercellular Communication	Although there was linear marginal gingival inflammation, no remarkable enlargement was noted at last appointment.	16104968
Vascular Diseases, vascular inflammations, Thrombus	Altered Intercellular Communication	Vascular inflammation, an important pathologic change in various human vascular diseases, may be involved in the thrombotic process of arteriovenous fistulas.	16105066
Inflammation, Thrombosis	Altered Intercellular Communication	This study demonstrated that the thrombosed arteriovenous fistula was characterized by marked inflammation.	16105066
Inflammation, Cardiac dysfunction	Altered Intercellular Communication	Adrenomedullin reflects cardiac dysfunction, excessive blood volume, and inflammation in hemodialysis patients.	16105071
Inflammation, Cardiac dysfunction, Cardiovascular Diseases	Altered Intercellular Communication	Plasma mAM reflects cardiac dysfunction, excessive blood volume, and inflammation better than ANP, BNP, and NE, resulting in a predictor of mortality and cardiovascular morbidity in hemodialysis patients with cardiovascular disease.	16105071
pancreatic juice, Pancreatitis, Inflammation, Abdominal Pain	Altered Intercellular Communication	In acute pancreatitis (AP), oral refeeding may stimulate pancreatic secretion, increasing the inflammation of the glandular tissue causing relapse of abdominal pain or even exacerbation of the disease.	16105125
Pancreatitis	Altered Intercellular Communication	Their risk appeared be associated with more intense or persistent pancreatic inflammation on the day before refeeding, and presence of peripancreatic fluid collections.	16105125
Inflammation	Altered Intercellular Communication	IL1-RN is an important anti-inflammatory cytokine that modulate the inflammation response by binding to IL1 receptors, and as a consequence inhibits the action of proinflammatory cytokines IL1alpha and IL1beta.	16106254
Inflammation, Blood Vessel	Altered Intercellular Communication	During vascular damage, endothelial cells may detach from the site of inflammation and be released into the peripheral blood.	16107582
Inflammation	Altered Intercellular Communication	This is likely due to increased acuity and chronic right upper quadrant inflammation in this population.	16108740
Inflammation, Atherosclerosis, Diabetes Mellitus	Altered Intercellular Communication	Thus, inflammation, atherosclerosis and impaired glucose tolerance are tightly interrelated disorders even in subjects without known diabetes mellitus.	16108851
Inflammation	Altered Intercellular Communication	Emerging data suggest that C-reactive protein (CRP), a marker of inflammation, is associated with functional properties of arteries.	16109328
Malignant neoplasm of urinary bladder, Inflammation	Altered Intercellular Communication	Polymorphisms in inflammation genes and bladder cancer: from initiation to recurrence, progression, and survival.	16110031
Malignant neoplasm of urinary bladder, Inflammation, Best Case Imputation Technique	Altered Intercellular Communication	Since chronic inflammation contributes to tumorigenesis, we hypothesized that the risk and clinical outcome of bladder cancer (BC) might be modulated by genetic variations in inflammation genes.	16110031
Doctor of Chiropractic, Inflammation	Altered Intercellular Communication	In the DCM group, endomyocardial biopsies were performed and evaluated for inflammation and viral genome.	16111918
PNS function, Inflammation	Altered Intercellular Communication	Markers of inflammation, vitamin E and peripheral nervous system function: the InCHIANTI study.	16112778
Inflammation, Lymphoma	Altered Intercellular Communication	Two additional cases were obscured by dense inflammation, again suggesting the diagnosis of lymphoma.	16115052
Airway structure, ARCN1 gene	Altered Intercellular Communication	The results suggest that LTB(4) is involved in airway inflammation in COPD.	16115390
Kidney Failure, Chronic, Inflammation, Cardiovascular morbidity	Altered Intercellular Communication	Inflammation may contribute to the markedly increased cardiovascular morbidity and mortality in end-stage renal disease (ESRD).	16115480
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	However, the prevalence of inflammation varies in different ESRD populations.	16115480
Inflammation	Altered Intercellular Communication	Furthermore, as the PPAR-gamma2 Pro12Pro genotype was associated with both higher levels of biomarkers of inflammation as well as shorter survival, genetic polymorphisms seem to play a role in determining systemic inflammatory status and outcome in this patient group.	16115480
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Association between Lp-PLA2 and coronary artery disease: focus on its relationship with lipoproteins and markers of inflammation and hemostasis.	16115490
Diabetic Nephropathy, Vascular Diseases, vascular inflammations, immunoglobulin A	Altered Intercellular Communication	Systemic and vascular inflammation is elevated in early IgA and type 1 diabetic nephropathies and relates to vascular disease risk factors and renal function.	16115854
Kidney Failure, Chronic, Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Electronic Source Report Form	Altered Intercellular Communication	Inflammation is implicated in cardiovascular disease (CVD) and mortality in end-stage renal failure (ESRF).	16115854
Inflammation, physiopathological	Altered Intercellular Communication	Inflammation and vascular dysfunction as measured by pulse pressure (PP) were related.	16115854
Renal Insufficiency, Inflammation, Kidney Diseases	Altered Intercellular Communication	Systemic and vascular markers of inflammation are increased in early renal disease and relate to renal dysfunction and cardiovascular risk factors.	16115854
Renal Insufficiency, Inflammation, Kidney Diseases	Altered Intercellular Communication	Inflammation may be a common process in various renal diseases and may link and accelerate renal dysfunction and CVD.	16115854
Communicable Diseases, Inflammation, Traumatic injury, Neoplasms	Altered Intercellular Communication	Serum amyloid A (SAA) is an acute phase reactant, whose level in the blood is elevated in response to trauma, infection, inflammation, and neoplasia.	16116035
Inflammation	Altered Intercellular Communication	All underwent a standardized assessment of the oral cavity and oral mucosal biopsy to characterize the number of sites affected and the type of inflammation involved.	16116319
Gastrointestinal inflammation	Altered Intercellular Communication	All 35 patients underwent ileocolonoscopy and biopsy to assess the presence of coexistent intestinal inflammation.	16116319
Inflammation, Gastrointestinal inflammation	Altered Intercellular Communication	Those with more severe oral inflammation were also more likely to have intestinal inflammation (P=0.025), and there was also a correlation between the histologic severity of oral inflammation and the histologic severity of gut inflammation (P=0.047).	16116319
Granulomatous inflammation, Gastrointestinal inflammation	Altered Intercellular Communication	OFG with associated intestinal inflammation may represent a separate entity in which granulomatous inflammation occurs throughout the gastrointestinal tract in response to an unknown antigen or antigens.	16116319
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Inflammation was controlled with topical steroids and the patient underwent a combined phacoemulsification and trabeculectomy with mitomycin-C for uncontrolled glaucoma.	16116512
Inflammation, Thrombosis, Autonomic nervous system disorders	Altered Intercellular Communication	The autonomic nervous system innervates the adventitia, and autonomic dysfunction induces many end-organ dysfunctions including inflammation and thrombosis.	16117998
Inflammation, Traumatic injury	Altered Intercellular Communication	The convergent response of adrenergia, inflammation, and coagulation, which is adaptive for physical trauma, may be maladaptive today when different stressors trigger the cascade.	16117998
Crohn Disease, Inflammation	Altered Intercellular Communication	Increased expression of the CCR7 ligands CCL19 by DC themselves as well as CCL21 by reticular cells and lymphatic vessels was observed in Crohn's disease, thereby causing the matured DC to be trapped at the site of inflammation.	16118351
Crohn Disease, Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Our results demonstrate that autocrine and paracrine actions of lymphoid chemokines in Crohn's disease may lead to increased numbers of mature DC away from their usual migration to lymphoid organs and result in the development of a tertiary lymphatic tissue within the bowel wall maintaining the autoimmune inflammation in Crohn's disease.	16118351
Inflammation, Dysplasia, Carcinoid Tumor, Cavernous lymphangioma, Adenomatous hyperplasia, Adenocarcinoma, Adenoma	Altered Intercellular Communication	Histopathologic evaluation after endoscopic papillectomy revealed adenoma (n=11, 50%), high-grade dysplasia (n=3, 13.6%), adenocarcinoma (n=2, 9.1%), carcinoid (n=1), chronic inflammation (n=3, 13.6%), papillary adenomatous hyperplasia (n=1), and cavernous lymphangioma (n=1).	16118521
Inflammation	Altered Intercellular Communication	The decreased concentration of high sensitivity C-reactive protein seen 30 days after percutaneous coronary intervention in those treated with bivalirudin is consistent with greater attenuation of inflammation that may have contributed to the trend toward reduced mortality 1 year later in those treated with bivalirudin in REPLACE-2.	16118546
Hypotension, CTCAE, Inflammation, Choroidal Effusions	Altered Intercellular Communication	: hypotension, inflammation were noticed particularly in group 1 and 3 and choroidal effusion only in group 1.	16118920
Inflammation	Altered Intercellular Communication	New therapeutic regimen caused the remission of inflammation and preserved patient's useful visual acuity.	16118962
Cerebrovascular, Inflammation, Atherosclerosis, Osage language	Altered Intercellular Communication	These results suggest that OSA-related hypoxia and systemic inflammation might be associated with the progression of atherosclerosis and thus might increase the risks of cardiovascular and cerebrovascular morbidity in patients with OSA.	16120716
Inflammation	Altered Intercellular Communication	Our objective was to examine the degree and pattern of (18)F-FDG uptake within the shoulder as a potential marker of joint inflammation or injury.	16120937
Inflammation, Pain Distress Question, Stiffness, Communicable Diseases, Arthritis, Swelling, Traumatic injury, Damage, metabolic disturbance	Altered Intercellular Communication	Arthritis is inflammation in a joint often with joint damage, usually accompanied by pain, swelling and stiffness, resulting from infection, trauma, degenerative changes, metabolic disturbances, autoimmune or other causes.	16122880
Inflammation, Arthritis	Altered Intercellular Communication	A dose-dependent inhibition of IL-1beta and TPA stimulated MMP activity by gallium nitrate at increasing concentrations occurs, demonstrating that gallium nitrate can be a useful modulator of inflammation in arthritis.	16122880
Pain Distress Question, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Pain and inflammation from rheumatoid arthritis diminished rapidly, and neither pain nor inflammation returned during the following 2 years from that single treatment.	16122880
Pain Distress Question, Arthritis, Inflammation	Altered Intercellular Communication	Proper use of gallium III may be effective in terminating pain and inflammation of arthritis for years, often with a single treatment.	16122880
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Although Idd21.1 did not influence beta-islet inflammation, splenocytes from pre-diabetic Idd21.1-congenic mice were less efficient at transferring diabetes to immunodeficient NOD-scid mice.	16123376
hydrocortisone, Inflammation	Altered Intercellular Communication	Coexistence of MS and HC synergistically accelerates inflammation and impairment of fibrinolysis via elevated concentrations of both TAFI and PAI-1, which inhibit fibrinolysis.	16123492
Communicable Diseases, Systemic Inflammatory Response Syndrome, Inflammation	Altered Intercellular Communication	In the history of TTS the infection and inflammation are closely interwoven: clinical recovery from immunocompromise is associated with the onset of SIRS.	16124385
Pharyngitis	Altered Intercellular Communication	The expression of EBV LMP2A was detected in the specimens of 40 patients with NPC and 38 cases with nasopharyngeal inflammation by S-P immunohistochemical methods.	16124641
Pharyngitis	Altered Intercellular Communication	Thirty-three of the 38 cases with nasopharyngeal inflammation showed negative expression of LMP2A.	16124641
Pharyngitis	Altered Intercellular Communication	There was a significant difference of LMP2A expression between NPC and nasopharyngeal inflammation.	16124641
IL13 gene	Altered Intercellular Communication	These results indicate that exposure BCG-PSN can correct the imbalance state of Th1 and Th2 cytokines and inhibit allergic airway inflammation and control allergic rhinitis.	16124647
Inflammation, Carcinogenesis	Altered Intercellular Communication	Several studies in recent years indicate that chronic inflammation is a cofactor in lung carcinogenesis.	16126303
Inflammation, Trauma, Nervous System	Altered Intercellular Communication	Clinical inflammation often precedes the detection of radiological damage.	16126794
Inflammation	Altered Intercellular Communication	The severity of inflammation and the density of H pylori were evaluated semiquantitatively.	16126872
Inflammation	Altered Intercellular Communication	The alterations correlate best with the severity of inflammation and not with H pylori density.	16126872
Presenile dementia, Inflammation	Altered Intercellular Communication	Chronic low-grade inflammation, as measured with the peripheral serum marker C-reactive protein (sCRP), may be a risk factor for dementia in elderly persons.	16127106
vascular inflammations, Hyperhomocysteinemia	Altered Intercellular Communication	No association was found between MMSE and peripheral markers of vascular inflammation other than sCRP, but lower MMSE scores were also independently associated with hyperhomocysteinemia (plasma tHcy > 15 mmol/L).	16127106
Inflammation, Impaired cognition	Altered Intercellular Communication	Results support the hypothesis that chronic low-grade inflammation may be involved in age-related cognitive impairment.	16127106
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Recently, it has been hypothesized that inflammation increases the risk of colorectal cancer.	16127232
Granulomatous inflammation, Neoplasms	Altered Intercellular Communication	Neurosurgeons should be aware of this rare tumor to avoid misdiagnosis as granulomatous inflammation.	16127261
Pneumonia, Interstitial, Interstitial inflammation, Pneumonia	Altered Intercellular Communication	Those with interstitial pneumonitis had bilateral basal opacities on chest X-ray, and histopathology showed mild lymphoplasmocytic interstitial inflammation, scattered intraalveolar epitheloid granulomas and a focal pattern of organizing pneumonia.	16127266
HD Term Type, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	A reverse association between cholesterol level and cardiovascular disease mortality is observed in hemodialysis (HD) patients; this paradoxical relationship may be explained by the coexistence of inflammation.	16127269
Periodontitis, Bacterial Infections	Altered Intercellular Communication	Periodontitis is a bacterial infection, which has been classified as a local chronic inflammation.	16127475
Inflammatory disease of mucous membrane	Altered Intercellular Communication	RT-PCR showed that MEF2b expression in non-inflamed mucosa was significantly downregulated, whereas the expression of MEF2b increased in accordance with the severity of mucosal inflammation.	16127744
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	It is suggested that the MEF2b expression in UC which increase in accordance with inflammation may be induced by the inflammatory mediator.	16127744
Pheochromocytoma, Adenoma	Altered Intercellular Communication	Hormonal evaluation and imaging showed a benign non-hyperactive functioning adenoma in one patient and a pheochromocytoma in the other.	16128177
Airway structure	Altered Intercellular Communication	This has been related to the physiological consequences of chronic airway inflammation causing airway remodeling.	16128222
Inflammation, Hyperplasia	Altered Intercellular Communication	The following parameters were analysed by ELISA: urinary levels of C-terminal cross-linking telopeptide of type II collagen (CTX-II), a marker of type II collagen breakdown; serum levels of hyaluronan (HA), a marker of synovial inflammation and hyperplasia; and circulating levels of stromelysin-1 (matrix metalloproteinase-3 [MMP-3]), collagenase-1 (MMP-1) and collagenase-3 (MMP-13).	16128596
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Patients with flare-up of their osteoarthritis disease process exhibit enhanced levels of markers of joint inflammation and cartilage collagen breakdown, which were markedly decreased by nimesulide but not by ibuprofen.	16128596
Achalasia, Inflammation	Altered Intercellular Communication	When achalasia becomes far advanced and leads to esophageal resection, inflammation of the esophageal mucosa is almost universal.	16128783
Necrotizing granulomatous inflammation	Altered Intercellular Communication	In conclusion, T. gondii should be taken into consideration as a rare cause of placental granulomatous inflammation.	16129485
Inflammation, Pain, Postoperative, Traumatic injury, Facet joint structure	Altered Intercellular Communication	Radiofrequency neurolysis of lumbar medial branch is currently the only proven way to treat patients with chronic lumbar zygapophysial joint pain, however, in some patients it can cause transient postoperative pain due to an inflammation caused by trauma of the electrode insertion and the thermal lesion around the target nerves.	16129914
Inflammation, Atherosclerosis	Altered Intercellular Communication	Low free testosterones coexist with inflammation and they both affect the process of atherosclerosis in old-age male.	16130198
Inflammation, Exanthema, Arthritis, Psoriatic	Altered Intercellular Communication	Discontinuation of therapy is associated with recurrence of symptoms of joint inflammation and increase in skin eruptions in patients with psoriatic arthritis within a few months.	16130600
Acute arthritis	Altered Intercellular Communication	These findings made us speculate that some pre-existing inflammatory conditions around the accessory bone induced deposition of urate crystals, and the destruction of the barrier between the deposits and the joint led to an acute arthritis.	16131688
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	A linkage between the activity of prostaglandin synthase enzyme cyclooxygenase-2 (COX-2), a known mediator of inflammation, and cancer angiogenesis is implicated.	16132759
Acute inflammation	Altered Intercellular Communication	The within patient variability was 0.37 for the entire cohort, and 0.33 when three patients with intercurrent acute inflammation were excluded.	16132776
Inflammation, Diverticulitis, Carcinoma	Altered Intercellular Communication	In three of these patients false-positive findings were observed, and MRC classified the inflammation of the sigmoid colon as diverticulitis whereas CC and histopathology confirmed invasive carcinoma.	16132933
Inflammation, Pouchitis	Altered Intercellular Communication	Increased cytokine transcripts in pouchitis reflect the degree of inflammation but not the underlying entity.	16133004
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	This increase is independent of the underlying disease (UC or CD) and reflects the degree of inflammation.	16133004
Inflammation	Altered Intercellular Communication	Quantification of transcript levels allows an estimation of the extent of mucosal inflammation and may become helpful in the evaluation of the disease, especially in clinical trials.	16133004
Ulcerative Colitis	Altered Intercellular Communication	Patients with active ileal CD (n=14), active UC (n=17) and non-inflammatory conditions (n=12) served as controls.	16133004
Inflammation, FAM126A gene	Altered Intercellular Communication	The present case suggests that HCC could develop in non-cirrhotic NASH liver, and that chronic inflammation in itself could be an important risk factor in the development of HCC.	16133366
Weakness, Osteopenia	Altered Intercellular Communication	This finding supports the postulated inflammation-associated bone loss pathogenesis as one of the causes of bone weakness in CD.	16133447
Inflammation	Altered Intercellular Communication	In one patient, inflammation recurred or did not disappear, and, therefore, three debridements were necessary.	16133473
Inflammation	Altered Intercellular Communication	In such examinations, thickening of the vessel wall and/or increased contrast enhancement demonstrate mural inflammation.	16133594
Inflammation, Small bowel obstruction	Altered Intercellular Communication	Small bowel obstruction due to inflammation secondary to ingested bone.	16133596
Inflammation, Tissue Adhesions, Traumatic injury	Altered Intercellular Communication	Laparotomy and histology of the resected small bowel confirmed the CT appearances that the obstruction was caused by adhesions and extensive inflammation across the bowel wall in the distal jejunum from trauma as the bone traversed down the lumen.	16133596
Inflammation, Tissue Adhesions, Small bowel obstruction	Altered Intercellular Communication	We believe that this is the first reported preoperative CT scan finding of a case of small bowel obstruction due to adhesions and inflammation secondary to ingested bone.	16133596
Osteoporosis, Osteopenia	Altered Intercellular Communication	Strategies to prevent bone loss and osteoporosis in Asian men should include lifestyle modification and maintenance of hormonal sufficiency.	16133639
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	The characteristic feature of chronic rhinosinusitis with nasal polyposis (CRSwNP) is eosinophilic inflammation of the sinus mucosa; a type of inflammation also seen in asthmatic airways.	16134994
Airway structure, asthma chronic, mucus secretion	Altered Intercellular Communication	Chronic asthma is characterized by airway inflammation, mucus hypersecretion and impaired mucociliary clearance (MCC).	16135164
Inflammation, ovarian neoplasm	Altered Intercellular Communication	Convincing data support the link between inflammation and ovarian cancer.	16135466
ovarian neoplasm, Tumor necrosis, Inflammation, Neoplasms	Altered Intercellular Communication	Tumor necrosis factor-alpha (TNF-alpha), a major mediator of inflammation, is chronically produced in the ovarian tumor microenvironment and may enhance tumor growth and invasion by inducing the secretion of cytokines, proangiogenic factors, and metalloproteinases.	16135466
ARCN1 gene, Myositis	Altered Intercellular Communication	Skeletal muscle inflammation and nitric oxide in patients with COPD.	16135718
ARCN1 gene, Inflammation, Congenital Abnormality, Chronic Obstructive Airway Disease, Weight decreased	Altered Intercellular Communication	In chronic obstructive pulmonary disease (COPD) the presence of systemic inflammation has been associated with peripheral muscle abnormalities and weight loss.	16135718
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	In conclusion, the present study shows an increased leptin expression in bronchial mucosa of chronic obstructive pulmonary disease patients, associated with airway inflammation and airflow obstruction.	16135719
Colorectal Carcinoma, Colitis	Altered Intercellular Communication	A pilot randomised controlled trial to reduce colorectal cancer risk markers associated with B-vitamin deficiency, insulin resistance and colonic inflammation.	16136044
Carcinogenesis, Colorectal Carcinoma, Colitis	Altered Intercellular Communication	Colorectal cancer risk is associated with biochemical markers for B-vitamin deficiency, insulin resistance and colonic inflammation, suggesting that these three conditions are each involved in colon carcinogenesis.	16136044
Colitis	Altered Intercellular Communication	Our supplemental strategy modestly affected some of the biomarkers associated with folate metabolism and insulin resistance, but had no effect on those associated with colonic inflammation.	16136044
Granulomatous inflammation, Chronic granulomatous disease, Infection	Altered Intercellular Communication	Most cases of CGD are diagnosed in children; however, it may rarely go undiagnosed until adulthood in individuals with unexplained infections and granulomatous inflammation.	16136772
Crohn Disease, Chronic granulomatous disease, Granulomatous inflammation	Altered Intercellular Communication	The concomitant occurrence of Crohn disease and CGD, both characterized by granulomatous inflammation, is noteworthy.	16136772
Inflammation, Osteopenia	Altered Intercellular Communication	Placement of implants with a minimally invasive flapless approach has the potential to minimize crestal bone loss, soft tissue inflammation, and probing depth adjacent to implants and to minimize surgical time.	16137084
Inflammation, Hemorrhage	Altered Intercellular Communication	The benefits of this procedure are lessened surgical time; minimal changes in crestal bone levels, probing depth, and inflammation; perceived minimized bleeding; and lessened postoperative discomfort.	16137084
Inflammation, Periodontal Diseases	Altered Intercellular Communication	To study the levels of systemic markers for inflammation with parameters of periodontal diseases in older people.	16137283
Inflammation, Dilated Cardiomyopathy Pathway	Altered Intercellular Communication	We investigated whether myocardial biopsy analysis for inflammation and viruses correlates with outcome in dilated cardiomyopathy.	16137516
Inflammation	Altered Intercellular Communication	Patients were attributed to three groups: (A) no inflammation/no virus (B) inflammation/no virus (C) virus with/without inflammation.	16137516
Inflammation, Atherosclerosis	Altered Intercellular Communication	Since inflammation is a major force driving atherosclerosis, and man lives in a postprandial period most part of the day, a reduced inflammatory response after a meal may delay progression of atherosclerosis.	16137694
Inflammation, Lung Injury	Altered Intercellular Communication	We speculated that a Th1 type of lung tissue inflammation or lung injury might be involved as a part of mechanisms underlying gefitinib-induced ILD.	16137874
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Illness (finding)	Altered Intercellular Communication	Asthma and chronic obstructive pulmonary disease (COPD) are common respiratory illnesses characterized by chronic inflammation of the airways.	16138219
Airway structure	Altered Intercellular Communication	The characterization of induced or spontaneously produced sputum is a useful technique to assess airway inflammation.	16138219
Inflammation, Infection caused by Helicobacter pylori, Atherosclerosis	Altered Intercellular Communication	These results suggest that inflammation following H. pylori infection contributes to the early stage of atherosclerosis in younger males.	16138557
Intraocular inflammation	Altered Intercellular Communication	A 55-year-old man developed post-cataract intraocular inflammation.	16139017
Inflammation, Pupil	Altered Intercellular Communication	Visual acuity, intraocular pressure, inflammation, and pupillary distortion.	16139667
Schizophrenia, Anxiety, CTCAE 3.0	Altered Intercellular Communication	Alterations in DHEA metabolism in schizophrenia are attributed to the distress, anxiety, severity of symptoms, prolactin levels, and may represent a marker for impaired hormonal responses to stress.	16139994
Inflammation, Renal function	Altered Intercellular Communication	All patients were monitored for any alteration in generalized condition, signs of inflammation, and liver and kidney function for the next 14 days.	16142359
Inflammation	Altered Intercellular Communication	Thus changes in liver protein synthesis rates in conjunction with catabolism and acute inflammation in man need to be characterized better.	16144514
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	We speculate that SEB initiates inappropriate immune reactions and inflammation in the colonic mucosa that further progresses to UC.	16144553
Inflammation	Altered Intercellular Communication	Furthermore, it may be involved in regulative processes taking place in insulin resistance and inflammation.	16144855
Proteinuria, Nephritis	Altered Intercellular Communication	These studies support animal data linking aldosterone/MR activation to renal inflammation and proteinuria.	16145013
Vaginitis, Mycoses	Altered Intercellular Communication	[Bacterial flora and mycosis of the vagina in women with symptoms of vaginal inflammation].	16145858
Inflammation	Altered Intercellular Communication	In 5 cases bacterial inflammation was caused by two kinds of bacterium.	16145858
Candida albicans, Inflammation	Altered Intercellular Communication	In all cases of inflammation mycosis was called out by from Candida albicans.	16145858
Candida albicans, Inflammation, Enterococcus faecalis	Altered Intercellular Communication	At two women it was Candida albicans and Streptococcus agalactiae, at one inflammation mycosis accompanied Enterococcus faecalis.	16145858
Mycoses	Altered Intercellular Communication	Mixed inflammations called out both by mycosis and bacterial stepped out in 3 cases in age of 21-30.	16145858
Inflammation, Coronary heart disease	Altered Intercellular Communication	[Related inflammation markers among different types of coronary heart disease].	16145923
Malignant neoplasm of urinary bladder, Myocarditis, Neoplasms	Altered Intercellular Communication	In practice diagnostic specificity of CA 125 concentration is lower as it is limited by the increase of concentration different tumour diseases (bladder cancer) and non-tumour diseases (pericardial inflammation).	16145993
Retinitis, Vitreous inflammatory cells	Altered Intercellular Communication	Eighteen days after the DLI, the funduscopic findings revealed improvement of the retinitis and the development of vitreous inflammation.	16146543
IL13 gene	Altered Intercellular Communication	The up-regulation of Toll-like receptors 2, 3 and 4 in the nasal mucosa of patients with symptomatic allergic rhinitis supports the idea of a role for Toll-like receptors in allergic airway inflammation.	16146574
With intensity, Optic Neuropathy, Ischemic	Altered Intercellular Communication	Intraorbital optic nerve signal hyperintensity on magnetic resonance imaging sequences in perioperative hypotensive ischemic optic neuropathy.	16148628
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	We also examined whether the laboratory markers of inflammation may be predictors of severe ischemic manifestations (visual ischemic events, cerebrovascular accidents, jaw claudication, or large-artery stenosis of the extremities of recent onset), and their potential correlation.	16148728
Inflammation, GCA gene, Complication Aspects, Anemia	Altered Intercellular Communication	In conclusion, our results suggest that some laboratory markers of inflammation, in particular the presence of anemia, may negatively predict the risk of severe ischemic complications in GCA patients.	16148728
Sepsis, Inflammation	Altered Intercellular Communication	Parenteral nutrition (PN) is preferred, but enteral nutrition (EN) promises to attenuate inflammation and prevent sepsis.	16149365
Inflammation, "Alzheimers Disease", Data types - Address, Cerebral atrophy	Altered Intercellular Communication	Inflammation, in the form of reactive astrocytes and microglia, is thought to play an important role in Alzheimer's disease (AD) pathogenesis where it correlates with brain atrophy and disease severity.	16150121
Aggressive course, Inflammation, Data types - Address	Altered Intercellular Communication	Despite having a more aggressive disease process and greater Abeta deposition, few studies have investigated inflammation in early onset AD cases with mutations in the presenilin-1 (PS-1) gene.	16150121
Inflammation, Dental Plaque	Altered Intercellular Communication	We investigated the association between inflammation and plaque pathology in PS-1 AD.	16150121
Inflammation, Data types - Address	Altered Intercellular Communication	These findings indicate potent stimulator(s) of inflammation that are not typical of the Abeta that accumulates in the pathological hallmarks of sporadic AD.	16150121
Arthritis	Altered Intercellular Communication	Their treatment was altered (following predefined algorithms) with the aim of suppressing both clinical and laboratory evidence of joint inflammation.	16153351
Inflammation, Tuberculosis, Renal, Atrophic, Urinary tract infection	Altered Intercellular Communication	It may be associated with, sometimes, aging, atrophy, long-standing chronic inflammation and urinary infection, such as renal tuberculosis.	16153545
Inflammation	Altered Intercellular Communication	YKL-40 is a newly discovered matrix protein thought to be secreted during the acute stages of inflammation.	16153848
Inflammation	Altered Intercellular Communication	It has recently been speculated that YKL-40 may serve as a specific serologic marker of neutrophil function at the site of acute tissue inflammation.	16153848
Parkinson Disease, Inflammation, palladium	Altered Intercellular Communication	Immune reaction-related inflammation may be important in the pathogenesis of Parkinson disease (PD).	16154792
Communicable Diseases, Inflammation	Altered Intercellular Communication	Essential fatty acids modulate inflammation and glucose metabolism and may alter infection risk.	16155282
Inflammation, Intervertebral Disk Displacement	Altered Intercellular Communication	CD-68 macrophages were evident in herniated lumbar disc tissue in 40% of the cases, but abundant inflammation was observed in only 18% of the cases.	16157010
Inflammation, Neurologic Deficits, Ischemic stroke	Altered Intercellular Communication	Plasma levels of lipophilic antioxidant vitamins in acute ischemic stroke patients: correlation to inflammation markers and neurological deficits.	16157235
Inflammation, Ischemic stroke	Altered Intercellular Communication	Acute ischemic stroke is a clinical condition accompanied by inflammation and oxidative stress.	16157235
Inflammation, Ischemic stroke	Altered Intercellular Communication	Plasma alpha- and beta-carotene concentrations were lower and levels of inflammation markers were higher among patients with acute ischemic stroke compared with normal controls.	16157235
Inflammation	Altered Intercellular Communication	Thus, the previously documented increase in oxidized lipoproteins, inflammation, and microglial activation during normal aging may contribute to the age-related increase in macrosialin expression.	16157452
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Inflammation plays an important pathogenic role in the initiation and progression of atherosclerotic plaque lesions.	16157948
Inflammation	Altered Intercellular Communication	C-reactive protein (CRP), which directly participates in plaque inflammation, induces vascular cell adhesion molecule-1 (VCAM-1) expression in endothelial cells.	16157948
Inflammation, Temporal Arteritis, Aortitis	Altered Intercellular Communication	The first patient presented with signs of systemic inflammation without signs of temporal arteritis or aortitis.	16159035
Inflammation, Giant Cell Arteritis	Altered Intercellular Communication	The clinical manifestations in all patients were attributed to chronic inflammation of the aorta caused by giant cell arteritis.	16159035
Inflammation, Giant Cell Arteritis, Aortic Diseases	Altered Intercellular Communication	Aortic disease associated with signs of systemic inflammation should trigger the suspicion of giant cell arteritis.	16159035
vascular inflammations	Altered Intercellular Communication	Genome scan of systemic biomarkers of vascular inflammation in the Framingham Heart Study: evidence for susceptibility loci on 1q.	16159603
vascular inflammations, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	Vascular inflammation plays a central role in atherosclerosis and inflammatory biomarkers predict risk of cardiovascular disease (CVD).	16159603
vascular inflammations	Altered Intercellular Communication	Thus, finding genes that influence systemic levels of inflammatory biomarkers may provide insights into genetic determinants of vascular inflammation and CVD.	16159603
Airway structure	Altered Intercellular Communication	Nature of airway inflammation and remodeling in chronic cough.	16159625
Inflammation, Retinal Artery Occlusion	Altered Intercellular Communication	To investigate the role of inflammation in acute retinal artery occlusion (RAO).	16159722
Psoriasis, Dermatologic disorders	Altered Intercellular Communication	Psoriasis is a common skin disorder that may be triggered by hormonal disturbances, among other factors.	16159734
Inflammation, HMOX1 gene	Altered Intercellular Communication	We conclude that Hsp32 is up-regulated in the elderly as well as in individuals with inflammation, and that the HS response of Hsp32 is different in monocytes as compared to lymphocytes.	16160909
Inflammation, Pancreatitis	Altered Intercellular Communication	The weak expression of lymphangiogenic cytokines in neoplastic cells and lymphatic vessel proliferation in peritumoural regions and chronic pancreatitis indicate that inflammation may be the reason for the low rate of lymphangiogenesis.	16161179
Inflammation, Hemorrhage	Altered Intercellular Communication	In the mucosal and submucosal connective tissue there were signs of chronic inflammation and, focally, small haemorrhages.	16161456
Inflammation	Altered Intercellular Communication	Increased NO production with the presence and the severity of inflammation supports the contribution of NO in the peri-implant inflammatory process.	16161739
Inflammation, Data types - Address	Altered Intercellular Communication	The exacerbation of skin inflammation of patients with AD in relation to the seasons was also evaluated.	16161918
Inflammation, Data types - Address, Allergy - Charge Type Reason	Altered Intercellular Communication	Evaluation of exacerbation of skin inflammation of patient with AD in for patient with monovalent allergy of airborne allergens.	16161918
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	In the group of patients sensitive to pollen allergens seasonal exacerbation of skin inflammation was predominant (over 90% of patients) and in the groups of patients sensitive to house dust mite and animal allergens the clinical manifestation of allergy for the whole year was observed in the most patients (77.1% and 57.1%).	16161918
Inflammation	Altered Intercellular Communication	Along with patient amelioration and inflammation regression the activity of anti-oxidative serum enzymes increased.	16161924
Inflammation, Non-alcoholic Fatty Liver Disease, fibrogenesis	Altered Intercellular Communication	Liver antioxidant enzyme activities were high in patients with NAFLD, reflecting an oxidative stress possibly involved in inflammation and fibrogenesis.	16162151
Vasculitis, inflammation or infection	Altered Intercellular Communication	Primary angiitis of the central nervous system should always be taken into consideration when suspected infectious inflammation of the central nervous system does not respond to treatment adequately.	16162278
Inflammation	Altered Intercellular Communication	Bronchial mucosal biopsy specimens exhibited chronic inflammation with eosinophilic infiltrations in three of these seven patients (43%).	16162738
Inflammation, Edema, Failure (biologic function)	Altered Intercellular Communication	In 4 patients MMF was judged ineffective due to failure to reduce the number of recurrences of severe inflammation compared with the previous therapeutic regime, or indeed occurrence of persistent macular oedema.	16163494
Inflammation, Carcinoma, Ulcerative Colitis, Adenocarcinoma, CEL gene, Adenomatous Polyposis Coli	Altered Intercellular Communication	As in ulcerative colitis, carcinomas in JP may develop along a dysplasia-carcinoma sequence resulting from permanent mechanical insults, inflammation, and repair rather than from an adenoma-carcinoma sequence as in familial adenomatous polyposis (FAP).	16164047
Airway structure, Asthma	Altered Intercellular Communication	The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: an observational study in adults with asthma.	16164444
Airway structure, Asthma	Altered Intercellular Communication	Assessment of eosinophilic airway inflammation may be helpful in the management of asthma.	16164444
Airway structure	Altered Intercellular Communication	This value of exhaled NO would seem to be the best for identifying significant eosinophilic airway inflammation.	16164444
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation is assessed to monitor progression, control and treatment of asthma.	16164445
Airway structure	Altered Intercellular Communication	The collection of exhaled breath condensate (EBC) provides a non-invasive alternative to induced sputum samples for the monitoring of airway inflammation.	16164445
Airway structure	Altered Intercellular Communication	Induced sputum is a reliable technique that can be used to assess markers of airway inflammation.	16164445
Inflammation, Dental Plaque, Osteopenia	Altered Intercellular Communication	Multivariate analysis showed that peri-implant marginal bone loss was significantly related to a daily consumption of >10 g of alcohol, tobacco use and increased plaque levels and gingival inflammation.	16164465
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	White blood cell (WBC) count is a marker of inflammation and has been associated with the development of cardiovascular disease.	16164887
Fibrosis Assessment, Hepatic inflammation, Liver Cirrhosis	Altered Intercellular Communication	Oxidant stress, as reflected in blood and urine by a wide range of pro- and antioxidant markers, is a significant feature of alcoholic cirrhosis, providing a mechanism by which alcohol intake may be linked to hepatic inflammation and fibrosis.	16165720
Proteinuria	Altered Intercellular Communication	Inflammation-associated proteinuria in acute, nonrenal disease is a common but poorly understood phenomenon.	16166167
Sepsis, Inflammation	Altered Intercellular Communication	Urine samples were collected at daily intervals for up to 23 days from 6 patients with surgery-induced inflammation and at hourly intervals for a 24-h period from 7 sepsis patients.	16166167
Proteinuria, Inflammation	Altered Intercellular Communication	Orosomucoid, usually present in plasma and urine in much lower concentrations than albumin, is increased in urine to concentrations equal to or higher than albumin in proteinuria associated with acute inflammation.	16166167
Inflammation	Altered Intercellular Communication	Orosomucoid in urine may be a more informative marker than albumin for inflammation.	16166167
Inflammation	Altered Intercellular Communication	Persistent interleukin-8 (IL-8) production contributes to chronic inflammation of the stomach.	16166417
Exacerbation of cGVHD	Altered Intercellular Communication	"Flare" phenomenon has been primarily reported as a transient increase in the number or intensity of lesions on bone scans in patients receiving hormonal or chemotherapy.	16166838
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation was measured after 7 and 14 days by using slit-lamp biomicroscopy.	16167290
Cataract, Acute inflammation	Altered Intercellular Communication	NSAIDs can effectively be used without concurrent administration of corticosteroids to control postoperative inflammation after uncomplicated cataract surgery.	16167290
Ulcer, Mucous Membrane, Diarrhea, Crohn Disease	Altered Intercellular Communication	In chronic diarrhea patients a lesion was found in 5 cases (62.5%), where mucosal atrophy were found in two patients who responded to a free gluten diet, and in 3 patients acute inflammations with ulcers were treated as Crohn's disease.	16167487
Lymphoma	Altered Intercellular Communication	This is clinically important in view of the increased risk of lymphoma associated with SS, compared with idiopathic nonspecific lacrimal inflammation.	16168486
Airway structure, Respiratory Hypersensitivity	Altered Intercellular Communication	Suplatast tosilate is an antiallergic drug that selectively suppresses Th2-cytokine production and inhibits airway hyperresponsiveness and eosinophilic airway inflammation.	16169790
Bacterial Infections, Conjunctivitis	Altered Intercellular Communication	Recurrent trichiasis was significantly associated with more severe preoperative trichiasis, bacterial infection, and severe conjunctival inflammation at 12 months.	16170117
Ischemia, Inflammation, Guillain-Barre Syndrome, Neoplasms, Paralysed, Traumatic injury, Myasthenia Gravis	Altered Intercellular Communication	Differential diagnosis of acute tetraparesis includes paraplegia caused by trauma, ischemia, inflammation or tumor, Guillain-Barre syndrome, periodic paralysis, myasthenia gravis, and dissociative paralysis.	16170648
Gingivitis, Dental Plaque	Altered Intercellular Communication	The Oral-B Hummingbird was safe and effective in reducing approximal plaque and gingival inflammation, and provides a useful alternative device for interdental cleaning.	16170973
Inflammation	Altered Intercellular Communication	Different mediators of inflammation, and chemoattraction from monocyte and macrophage supernatants, plasma, and cerebral spinal fluid were identified in HIV-1-associated dementia versus normal cognition.	16171574
Traumatic injury	Altered Intercellular Communication	Patients with trauma, hemodialysis access, endovenous ablation, known AVF, or inflammatory conditions were excluded.	16171599
Inflammation	Altered Intercellular Communication	Due to severe periodontal inflammation, all primary teeth were extracted prior to the eruption of the first permanent tooth.	16173228
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Synovial inflammation in rheumatoid arthritis (RA) leads to pannus tissue invasion and destruction of cartilage/bone matrix by proteinases.	16173240
Inflammation, Fibrosis Assessment, Cholestasis	Altered Intercellular Communication	Hepatic histology (fibrosis, portal inflammation, ductular proliferation and cholestasis) was independently graded by two pathologists using a previously validated scale.	16174070
Inflammation, Observation Method - Coagulation, Traumatic, Hypothermia due to exposure	Altered Intercellular Communication	Effect of hypothermia on serum electrolyte, inflammation, coagulation, and nutritional parameters in patients with severe traumatic brain injury.	16174912
Ischemia	Altered Intercellular Communication	This profile was interpreted as inconsistent with ischemia (as defined by reduced DAV and NAA) but compatible with perihematoma inflammation (as defined by elevated DAV and lactate signal).	16174964
Inflammation, Hematoma	Altered Intercellular Communication	We postulate that mass effect produced by the hematoma, and perhaps inflammation, can induce perilesional reduced cerebral perfusion in a reversible manner.	16174964
Neoplasms, caruncle, Nevus, Pyogenic granuloma, Papilloma	Altered Intercellular Communication	The most frequent tumors of the caruncle are papilloma, nevi, pyogenic granuloma, epithelial inclusion cyst and chronic inflammation.	16175484
Cranial nerve palsies, Inflammation, Chronic Headache, Cerebellar Ataxia	Altered Intercellular Communication	Chronic headache, ataxia and cranial nerve palsies in combination with inflammation and dural thickening should call to mind idiopathic hypertrophic cranial pachymeningitis.	16175486
Inflammation, polyps, Hyperplasia	Altered Intercellular Communication	Abnormal endometrium included inflammation, polyp, hyperplasia and malignant changes.	16176522
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Patients with rheumatoid arthritis (RA) frequently display an atherogenic lipid profile which has been linked with inflammation.	16176811
Inflammation, Histopathology	Altered Intercellular Communication	Liver histopathology alterations, namely architectural staging, periportal and lobular inflammation as well as portal inflammatory infiltrate were graded from 0 to 4 and afterwards divided into light (0 to 2) and severe (3 to 4).	16177656
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	When we compared mild with severe histopathological alterations older age was significantly (p = 0.004) associated with severe fibrosis, periportal inflammation and portal inflammatory infiltrate.	16177656
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Additionally, platelets were significantly lower in severe fibrosis and in periportal inflammation.	16177656
Inflammation	Altered Intercellular Communication	Premalignant conditions that develop in the presence of chronic inflammation are often associated with the development of a more pronounced humoral immune response during progression of the disease.	16177953
Primary malignant neoplasm	Altered Intercellular Communication	It may be that this shift, which is similar to that found in other chronic inflammatory conditions, contributes to an increased cancer risk in BO.	16177953
Inflammation, Dental Plaque, Gingival Hemorrhage	Altered Intercellular Communication	After 6 months, subjects rinsing with the CPC rinse showed 15.4% less gingival inflammation, 33.3% less gingival bleeding, and 15.8% less plaque relative to the placebo group.	16178130
Inflammation, Intradermal Route of Drug Administration	Altered Intercellular Communication	However, activation of systemic and peritoneal inflammation may appear during the use of ID and to a lesser extent during use of AA.	16178478
Communicable Diseases, Inflammation, Headache	Altered Intercellular Communication	Patients who experienced headache had a significantly higher frequency of history of infection (P= .009) or inflammation (P= .045), as well as higher body temperature (P= .021), leukocyte count (P= .038), ESR (P= .011), and mass effect (P= .017) on admission.	16178955
Inflammation, Headache, COL4A2 wt Allele	Altered Intercellular Communication	Headache at ICH onset is associated with clinical and biochemical markers of inflammation and is an independent predictor of higher residual cavity volume after spontaneous ICH.	16178955
Crohn Disease, Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) and Crohn's disease (CD) are characterized by intestinal inflammation mainly caused by a disturbance in the balance between cytokines and increased complement (C) activation.	16179087
Impaired cognition	Altered Intercellular Communication	This new rating scale provides indirect evidence that localization of WMH within neurotransmitter systems may contribute to cognitive decline.	16179569
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Systemic and upper and lower airway inflammation at exacerbation of chronic obstructive pulmonary disease.	16179639
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	In addition to pulmonary involvement, stable chronic obstructive pulmonary disease (COPD) is associated with nasal and systemic inflammation.	16179639
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	Although exacerbations of COPD are associated with increased pulmonary and systemic inflammation, determinants of the systemic response remain obscure, and nor is it known whether there is nasal involvement.	16179639
ARCN1 gene, Inflammation	Altered Intercellular Communication	To investigate upper airway, lower airway, and systemic inflammation at exacerbation of COPD.	16179639
ARCN1 gene, Inflammation	Altered Intercellular Communication	Exacerbation of COPD is associated with greater nasal, sputum, and serum inflammation than the stable state.	16179639
Airway structure	Altered Intercellular Communication	The degree of upper airway inflammation correlated with the degree of lower airway inflammation (e.g., nasal wash/sputum myeloperoxidase; r = 0.50, p = 0.001).	16179639
Airway structure, Inflammation	Altered Intercellular Communication	The degree of systemic inflammation correlated with the degree of lower airway inflammation (e.g., serum IL-6/sputum IL-8; r = 0.35, p = 0.026), and was greater in the presence of a sputum bacterial pathogen (29.0 g/dl C-reactive protein difference, p = 0.002).	16179639
ARCN1 gene, Inflammation	Altered Intercellular Communication	Exacerbation of COPD is associated with pan-airway inflammation; the systemic inflammatory response is proportional to that occurring in the lower airway and greater in the presence of a bacterial pathogen.	16179639
Respiratory Hypersensitivity, Inflammation, AHR wt Allele	Altered Intercellular Communication	Knockout mice lacking T-bet develop airway hyperresponsiveness (AHR) to methacholine, peribronchial eosinophilic and lymphocytic inflammation, and increased type III collagen deposition below the bronchial epithelium basement membrane, reminiscent of both acute and chronic asthma histopathology.	16179640
vascular inflammations, Coronary Artery Disease	Altered Intercellular Communication	Homocysteine, cytokines (IL-18, IL-6, IL-8) are involved in vascular inflammation and coronary artery disease.	16179748
Inflammation, Meckel Diverticulum, Cestode Infections, Intestinal Volvulus, Peripheral Vascular Diseases	Altered Intercellular Communication	Twelve patients aged below 10 years (median 28 days) had patent vitelline ducts (PVDs), 3 children aged 13 months, 13 years and 14 years respectively had Meckel's diverticulum (MD), presenting as inflammation, tapeworm incarceration and volvulus respectively.	16180393
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Chronic inflammation induced by Helicobacter pylori infection is closely associated with epithelial cell proliferation and apoptosis, which are related to cellular turnover in gastric mucosa.	16181363
Stomatitis	Altered Intercellular Communication	Semiquantitative immunohistochemistry and Western blotting results for Reg expression were significantly associated with polymorphonuclear neutrophil activity and chronic inflammation of gastric mucosa.	16181363
Inflammation	Altered Intercellular Communication	There was also a positive association between increasing inflammation of the fungiform papillae and a history of both burning the tongue easily and irritation of the tongue by food.	16181454
Inflammation, Irritation, Atopy	Altered Intercellular Communication	Atopic people are more likely than the normal community to have inflammation of the fungiform papillae of their tongue which correlates with a history of a sensitive tongue manifest as irritation by heat and certain foods.	16181454
Airway structure, ARCN1 gene	Altered Intercellular Communication	Yufeining could improve lung function, decrease sputum TCC, absolute neutrophil count and IL-8 concentration, and relieve airway inflammation in patients with COPD in the stable phase.	16181530
Inflammation, Observation Method - Coagulation, Coronary heart disease	Altered Intercellular Communication	Elevated markers of inflammation and coagulation are found in patients with coronary heart disease.	16182391
Inflammation, Metabolic Syndrome X, Chronic Kidney Diseases	Altered Intercellular Communication	Associations of metabolic syndrome with inflammation in CKD: results From the Third National Health and Nutrition Examination Survey (NHANES III).	16183411
Inflammation, Metabolic Syndrome X, Chronic Kidney Diseases	Altered Intercellular Communication	Although metabolic syndrome is associated with inflammation in the general population, it is unknown whether similar associations exist in patients with chronic kidney disease.	16183411
Inflammation, Obesity, Abdominal, Metabolic Syndrome X, Hypertension, CTCAE	Altered Intercellular Communication	When all 5 components of metabolic syndrome were included in the same model, only hypertension, abdominal obesity, and low high-density lipoprotein level were associated significantly with inflammation in all 3 groups.	16183411
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	There also was a graded association between number of component conditions of metabolic syndrome and inflammation within each creatinine-clearance group.	16183411
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome is associated with inflammation in patients with varying levels of kidney function.	16183411
Inflammation, Necrosis	Altered Intercellular Communication	The extent of inflammation and necrosis was assessed to define the CTSI.	16183486
Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Interaction between inflammation-related gene polymorphisms and cigarette smoking on the risk of myocardial infarction in the Physician's Health Study.	16184405
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is known to be a major component of atherosclerosis, and cigarette smoking is known to induce a systemic inflammatory response.	16184405
Nonulcer dyspepsia, Peptic Ulcer, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The objective of this study was to investigate a potential association between serum CagA positivity, severity of gastric mucosal inflammation and eradication success among peptic ulcer and non-ulcer dyspepsia patients.	16185577
Encephalitis, Hydrocephalus	Altered Intercellular Communication	Ten days later, secondary brainstem inflammation with hydrocephalus appeared and led to the detection of L. monocytogenes during external ventricular bypass.	16185855
Inflammation, Overdiagnosis	Altered Intercellular Communication	The limitations of the study were ulcerations or inflammation that caused overdiagnosis in the AF observation.	16185965
Inflammation, Blood Clot, atherosclerotic	Altered Intercellular Communication	These findings suggest that LIGHT could serve as a molecular link between lipid metabolism, inflammation, and thrombus formation, which are all features of atherosclerotic plaques.	16186421
Pigmentation Disorders	Altered Intercellular Communication	Most of the pigmentation disorders (60.94%) were of post-inflammation origin.	16187956
Pain Distress Question, Inflammation, Edema	Altered Intercellular Communication	Moderate to severe pain was associated with the application of the red light, and mild inflammation with edema of the lower lip occurred.	16188193
Hormone abnormality, Family history	Altered Intercellular Communication	Clustering of FH, hormonal abnormalities, and high hs-CRP is associated with MES in Chinese middle-aged men.	16189249
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Diarrhea, Crohn Disease, Pouchitis	Altered Intercellular Communication	Indications included differentiating ulcerative colitis (UC) from Crohn's disease (CD) in established patients with IBD (13%); establishing a diagnosis in patients with atypical signs of inflammation as detected by endoscopy, histology, or radiology (50%); evaluation of chronic diarrhea (22%); evaluation of a family history of IBD (4%); and differentiating pouchitis from CD (4%).	16189419
Inflammation, Chronic diarrhea	Altered Intercellular Communication	Serological testing for ANCA/ASCA may have a significant role in the diagnosis and treatment in individuals presenting with sigmoid inflammation or atypical inflammation but was less useful in those with chronic diarrhea.	16189419
Inflammation, Anemia, Leukopenia	Altered Intercellular Communication	The authors describe a 4-year-old girl with severe anemia, neutropenia, inflammation, and severe growth failure.	16189440
Iron-Refractory Iron Deficiency Anemia, Inflammation	Altered Intercellular Communication	The authors describe this case as an inborn error of zinc metabolism caused by dysregulation of calprotectin metabolism, which mainly presented with the features of microcytic anemia and inflammation.	16189440
Inflammation, Dermatitis, Allergic Contact	Altered Intercellular Communication	Tacrolimus may be effective for allergic contact dermatitis patients who cannot avoid repeated allergen exposure, as it may not only reduce inflammation but inhibit recurrences.	16191019
Cardiovascular Diseases	Altered Intercellular Communication	Association between novel indices of malnutrition-inflammation complex syndrome and cardiovascular disease in hemodialysis patients.	16191065
Inflammation, Malnutrition, Cardiovascular Diseases, HD Term Type, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	Inflammation and malnutrition are recognized as important risk factors for cardiovascular disease (CVD) in hemodialysis (HD) patients.	16191065
Malnutrition	Altered Intercellular Communication	PINI and LBM are associated with increased relative risk for having CVD and could be used routinely to examine the degree of severity of malnutrition inflammation complex syndrome.	16191065
Dementia, Vascular	Altered Intercellular Communication	These data suggest neurotransmitter systems as a potential therapeutic target in vascular dementia.	16191222
Communicable Diseases, Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Newer therapies to reduce the risk of infection and inflammation promise to further reduce the risk of first and recurrent stroke and are undergoing testing.	16191235
Inflammation, Fatty degeneration	Altered Intercellular Communication	A repeat liver biopsy done 13 months after the initial biopsy revealed a substantial decrease in steatosis and a reduction in inflammation.	16191492
T-Cell Lymphoma, Orbital Pseudotumor	Altered Intercellular Communication	A rapidly fatal case of T-cell lymphoma presenting as idiopathic orbital inflammation.	16191803
Orbital Pseudotumor	Altered Intercellular Communication	A 41-year-old Caucasian woman presented with a painful, red right eye with minimal systemic symptomatology, and was initially diagnosed with right idiopathic orbital inflammation.	16191803
Orbital Pseudotumor	Altered Intercellular Communication	Thorough physical examination with early orbital biopsy should be considered to exclude underlying treatable pathology in managing patients with presumed idiopathic orbital inflammation.	16191803
Inflammation, Infection, RTEL1 gene	Altered Intercellular Communication	Findings suggest that inflammation, infections, susceptibility to infections, and/or use of antibiotics or nonsteroidal anti-inflammatory drugs to treat these conditions may increase the risk of NHL.	16192343
Airway structure, Asthma	Altered Intercellular Communication	Because they have chronic airway inflammation, adults with asthma could have symptomatic exacerbation after exposure to second hand smoke (SHS).	16192366
Granuloma, Pancreatitis, Vocal Cord Paralysis, Rectum, Adenoma, Neoplasms, Gastro-esophageal reflux disease with esophagitis, Colonic adenomas, Diverticulitis, Fracture, Adenolymphoma, Arthritis	Altered Intercellular Communication	Benign tumors and inflammatory lesions included eight colon adenomas, four Warthin's tumors, one granuloma of the lower jaw, one adenoma of the thyroid gland, one compensatory muscle activity due to vocal chord palsy, two occurrences of arthritis, three occurrences of reflux esophagitis, two occurrences of pancreatitis, two occurrences of diverticulitis, one hemorrhoidal inflammation, and one rib fracture.	16192576
Pseudotumor	Altered Intercellular Communication	Inflammatory pseudotumor of the liver is an infrequent, fibroinflammatory non-neoplastic process of unknown etiology, generally following a benign inflammatory condition.	16192904
Cessation of life, Electrocardiogram: myocardial infarction (finding), Pain in calf	Altered Intercellular Communication	Incidence of myocardial infarction and death in relation to walking-induced calf pain and plasma levels of inflammation-sensitive proteins.	16193189
Pain Distress Question, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Walking-induced calf pain as well as levels of different inflammation-sensitive plasma proteins (ISPs) are related to cardiovascular disease (CVD).	16193189
Inflammation, Swelling, Pain Distress Question	Altered Intercellular Communication	Inflammation (two out of three criteria: redness at insertion site, pain on palpation or swelling) was found in 146 patients (4.2% of all cases).	16193317
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Elevated platelet microparticles in stable coronary artery disease are unrelated to disease severity or to indices of inflammation.	16194867
Acute myocardial infarction, Angina, Unstable, Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Platelet microparticles (PMPs), procoagulant membrane vesicles derived from activated platelets, are elevated in acute myocardial infarction and unstable angina but their relationship to inflammation and indices of coronary artery disease are unclear.	16194867
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	YKL-40, a growth factor of connective tissue cells, is elevated in sera from patients with diseases characterized by inflammation, tissue remodelling, or fibrosis.	16195162
Bronchial Hyperreactivity, Bronchitis	Altered Intercellular Communication	Asthma is characterized by bronchial inflammation and hyperresponsiveness that involves mast cell tryptase and potentially its specific receptor protease activated receptor 2 (PAR-2).	16195539
ARCN1 gene, Inflammation	Altered Intercellular Communication	Muscarinic receptors, leukotriene B4 production and neutrophilic inflammation in COPD patients.	16197467
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Acetylcholine (ACh) plays an important role in smooth muscle contraction and in the development of airway narrowing; preliminary evidences led us to hypothesize that ACh might also play a role in the development of airways inflammation in chronic obstructive pulmonary disease (COPD).	16197467
Airway structure, ARCN1 gene	Altered Intercellular Communication	The results obtained show that muscarinic receptors may be involved in airway inflammation in COPD subjects through ACh-induced, ERK1/2-dependent LTB4 release.	16197467
Inflammation, atherosclerotic, Diabetes Mellitus	Altered Intercellular Communication	The relationship between chronic low-grade inflammation and atherosclerotic progress in patients with diabetes mellitus has not been confirmed.	16199026
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1, Hypersensitivity, Inflammation	Altered Intercellular Communication	Development of spontaneous multisystem autoimmune disease and hypersensitivity to antibody-induced inflammation in Fcgamma receptor IIa-transgenic mice.	16200626
Autoimmune Diseases, Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	The presence of enhanced passive and induced autoimmunity, as well as the emergence of spontaneous autoimmune disease at 20-45 weeks of age, suggest that FcgammaRIIa is a very important factor in the pathogenesis of autoimmune inflammation and a possible target for therapeutic intervention.	16200626
Multiple Organ Failure, Granulomatous inflammation, Common Variable Immunodeficiency	Altered Intercellular Communication	A 22-year-old white man with CVID developed acute multiorgan failure, with granulomatous inflammation on lung and liver biopsy specimens.	16200822
Inflammation, Ischemic, Cerebrovascular accident	Altered Intercellular Communication	Erythrocyte sedimentation rate as a marker of inflammation and ongoing coagulation in stroke and transient ischaemic attack.	16201006
Communicable Diseases, Inflammation, Thrombus	Altered Intercellular Communication	Systemic infection and inflammation have been implicated in the aetiology of thrombotic cerebral events, particularly in younger patients.	16201006
Inflammation, Thrombosis, Communicable Diseases, Tacca leontopetaloides, Ischemic	Altered Intercellular Communication	We decided to determine whether those patients with raised D-dimer levels, indicating continuing thrombosis and fibrinolysis, had evidence of concurrent infection or inflammation as manifested by a raised erythrocyte sedimentation rate (ESR) measured after an ischaemic stroke/transient ischaemic attack (TIA).	16201006
Inflammation	Altered Intercellular Communication	When analysing other markers of inflammation/infection in association with raised D-dimer levels and ESR, mean fibrinogen levels were significantly raised at 6.56 g/l (p = 0.0122).	16201006
Bronchitis	Altered Intercellular Communication	In group B, the level of TNF-alpha was higher than in group C, but there was no significant difference in the level of IL-8 between group B and group C. It was concluded that the inflammatory cytokines, TNF-alpha and IL-8, played important roles in the bronchus allergic inflammation.	16201269
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	The serum ALT values, HBV DNA levels and hepatic inflammation and fibrosis were analyzed by their serum HBeAg status.	16202251
Communicable Diseases, Urethritis	Altered Intercellular Communication	Gram stain is used to detect urethral inflammation, suggestive of infection, in men and guide therapeutic decisions.	16205305
Inflammation, Chlamydia, Gonorrhea	Altered Intercellular Communication	Determine the proportion of men with chlamydia or gonorrhea diagnosed by nucleic acid amplification testing (NAAT) or culture who lack Gram stain evidence of inflammation and compare their clinical characteristics to men with inflammation.	16205305
Urethritis, Gonorrhea	Altered Intercellular Communication	Twelve percent of chlamydial and 5% of gonococcal infections had no Gram stain evidence of urethral inflammation.	16205305
PTHLH gene	Altered Intercellular Communication	In most patients, HHM is associated with over-production of a peptide analogue of parathormone (parathyroid hormone-related protein, PTHrP).	16205603
Inflammation	Altered Intercellular Communication	The complete rotation of the gall bladder followed by acute inflammation is a very rare and dangerous event.	16205866
Inflammation, Fibrosis Assessment, Diabetes Mellitus	Altered Intercellular Communication	The increased beta cell apoptosis in type 1 diabetes was accompanied by both increased macrophages and T lymphocytes and a marked increase in periductal fibrosis (p<0.001), implying chronic inflammation over many years, consistent with an ongoing supply of beta cells.	16205882
Neurologic Symptoms	Altered Intercellular Communication	Our report confirms that, even in cases of giant sellar mass with neurological symptoms, a rapid hormonal evaluation is mandatory.	16205966
Vitreous inflammatory cells	Altered Intercellular Communication	An increase of visual acuity together with a reduction of vitreous inflammation occurred.	16205976
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Beta-thalassemia major is associated with impaired endothelial function and increased levels of IL-6, sVCAM-1 and sICAM-1, suggesting a potential role of inflammation and endothelial dysfunction in the complications of the disease.	16207549
Inflammation, Chronic diarrhea, Fever, CTCAE	Altered Intercellular Communication	Genomospecies 2 strains were more frequently isolated from immunocompetent patients and/or patients without concomitant infections that presented with fever, chronic diarrhea, and gut inflammation than was genomospecies 1, clustering with the type strain of oral origin.	16207968
Inflammation	Altered Intercellular Communication	In addition, strategies to control ARMD may evolve quickly as more is learned about how specific molecular events, such as cell-mediated inflammation and angiogenesis, contribute to disease expression.	16208185
Retinal Vein Occlusion, Intraocular inflammation, Diabetes Mellitus, CTD gene	Altered Intercellular Communication	The causes of ME included diabetes (24 eyes), postoperative ME (four eyes), intraocular inflammation (three eyes), retinal vein occlusion (three eyes), and Coats disease (one eye).	16208226
Sacroiliitis, Spondylarthritis, Spondylitis	Altered Intercellular Communication	Spondyloarthritis research Consortium of Canada magnetic resonance imaging index for assessment of sacroiliac joint inflammation in ankylosing spondylitis.	16208659
Sacroiliitis, Spondylitis	Altered Intercellular Communication	To develop a feasible magnetic resonance imaging (MRI)-based scoring system for sacroiliac joint inflammation in patients with ankylosing spondylitis (AS) that requires minimal scan time, does not require contrast enhancement, evaluates lesions separately at each articular surface, and limits the number of sacroiliac images that are scored.	16208659
Inflammation, Spondylarthritis	Altered Intercellular Communication	The Spondyloarthritis Research Consortium of Canada MRI index is a feasible and reproducible index for measuring sacroiliac joint inflammation in patients with AS.	16208659
Inflammation, Fatigue	Altered Intercellular Communication	Participants described physical, cognitive, and emotional components and attributed fatigue to inflammation, working the joints harder, and unrefreshing sleep.	16208668
Airway structure, Fibrosis Assessment	Altered Intercellular Communication	Lower airway inflammation in infants with cystic fibrosis detected by newborn screening.	16208679
Airway structure, Fibrosis Assessment	Altered Intercellular Communication	Controversy exists over whether the lower airway inflammation that characterizes cystic fibrosis (CF) is initiated primarily by the genetic defect.	16208679
Communicable Diseases, Inflammation	Altered Intercellular Communication	In contrast, minimal or reduced signs of inflammation accompanied absence of eradication of infection from BAL fluid.	16208679
Airway structure, Communicable Diseases	Altered Intercellular Communication	We conclude that in CF, infection initiates and sustains airway inflammation.	16208679
Inflammation, Obesity	Altered Intercellular Communication	The significant association of severe obesity in nondiabetic and normotensive patients suggests that other obesity-associated mechanisms such as insulin resistance and inflammation should be further explored.	16209988
helium, Hepatic Encephalopathy	Altered Intercellular Communication	One proposed mechanism whereby hepatic encephalopathy (HE) leads to loss of brain function is dysregulated synthesis of neurosteroids.	16210399
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation is associated with increased energy expenditure in patients with chronic kidney disease.	16210709
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation, a clinical condition observed in patients with chronic kidney disease (CKD), may be related to increased resting energy expenditure (REE).	16210709
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The main objective was to investigate the relation between inflammation and REE in patients with CKD who are not undergoing dialysis.	16210709
Communicable Diseases, Inflammation	Altered Intercellular Communication	REE was measured before and after treatment in 10 patients who had inflammation or infection.	16210709
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	This study showed that inflammation is associated with increased REE in patients with CKD.	16210709
Rheumatoid Nodule, Necrosis	Altered Intercellular Communication	In both cases, the lung biopsy showed necrosis surrounded by epithelioid mononuclear inflammation with giant cells, consistent with rheumatoid lung node.	16211338
Inflammation, Phagocytosis	Altered Intercellular Communication	The excised vertebral and epidural lesions, 2 paraspinal biopsies, and tibial biopsy were interpreted as chronic inflammation until large histiocytes were noted, which were positive for CD68, S100 protein, fascin, and MAC387, and demonstrated characteristic emperipolesis (lymphophagocytosis) that was diagnostic of Rosai-Dorfman disease.	16211443
Inflammation	Altered Intercellular Communication	The pouch mucosa undergoes adaptive changes, with inflammation of the ileal reservoir being the most common complication.	16211713
Hematoxylin and eosin stain method, Inflammation	Altered Intercellular Communication	Biopsies were stained with H&E and scored for inflammation and morphological changes.	16211713
Inflammation, Cyst of stomach, Malignant Neoplasms	Altered Intercellular Communication	Gross anatomy and histology showed a gastric cyst measuring 150 mm in maximum diameter with no evidence of malignancy or inflammation.	16211721
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) patients have increased neutrophils and macrophages in their lungs, and inflammation of the airway is related to oxidative stress.	16213701
Inflammation	Altered Intercellular Communication	The joint manifestations and laboratory tests for inflammation improved.	16213770
Inflammation, Depression, CTCAE, Coronary heart disease	Altered Intercellular Communication	Self-rated health and vital exhaustion, but not depression, is related to inflammation in women with coronary heart disease.	16214026
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Chronic inflammation is associated with processes that contribute to the onset or progression of cancer.	16214925
Inflammation, Disease	Altered Intercellular Communication	Inflammation might be one of the causes of stone disease.	16215317
Inflammation	Altered Intercellular Communication	The function of the transporter associated with antigen-processing protein (TAP) is related to immune response and inflammation.	16215317
Inflammation	Altered Intercellular Communication	These findings show for the first time that plasma PLTP activity is associated positively with CRP in CVD, a state of chronic inflammation.	16216472
Inflammation, Perforation (observation), Toxic effect, Necrosis, Clostridium difficile	Altered Intercellular Communication	Clostridium difficile is a toxin-producing bacterium that is responsible for toxicity to the colonic mucosa, causing inflammation, necrosis, and, in some extreme cases, intestinal dilation and perforation.	16216661
Inflammation	Altered Intercellular Communication	The proteins have anti-microbial properties, and S100A8 may play a role in oxidant defense in inflammation.	16216873
Increased insulin level, Inflammation	Altered Intercellular Communication	Hyperinsulinemia provokes synchronous increases in central inflammation and beta-amyloid in normal adults.	16216936
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Inflammation has been implicated as a pathogenetic factor in Alzheimer disease, possibly via effects on beta-amyloid (Abeta).	16216936
Increased insulin level, Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Hyperinsulinemia induces inflammation and is a risk factor for Alzheimer disease.	16216936
Inflammation	Altered Intercellular Communication	Microscopic examination revealed, surprisingly, pancreatic tissue in the submucosa of the ileum with inflammation and transmural perforation.	16219192
Parkinson Disease, Inflammation, Hypopigmentation disorder, Striatonigral Degeneration	Altered Intercellular Communication	The pathogenesis of idiopathic Parkinson's disease is unknown, but nigral degeneration and depigmentation are associated with microglial inflammation and anti-inflammatory medications appear to protect against the disease.	16219675
Cessation of life, Inflammation, Parkinson Disease	Altered Intercellular Communication	The possibility that humoral immunity may play a role in initiating or regulating the inflammation has been suggested by experimental studies triggering dopamine cell death using a variety of transfer strategies and the observation of CD8+ T lymphocytes and complement in the nigra in Parkinson's disease.	16219675
Inflammation	Altered Intercellular Communication	Although all patients had increased inflammatory HLA immunopositive microglia, the degree of inflammation was similar throughout the disease (r = 0.08, P = 0.82).	16219675
Inflammation, Edema, Synovitis	Altered Intercellular Communication	MRI scans of the dominant wrist were scored for synovitis, tendon inflammation, bone oedema, and erosion at first presentation (n = 42), at 1 year (n = 42), and at 6 years (n = 31).	16219706
Inflammation, Hypoxia, Anemia, hepcidin	Altered Intercellular Communication	Hepcidin, a regulator for iron homeostasis, is induced by inflammation and iron burden and suppressed by anemia and hypoxia.	16220548
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Serum hyaluronate as a non-invasive marker of hepatic fibrosis and inflammation in HBeAg-negative chronic hepatitis B. HBV infection is a serious global heath problem.	16221307
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We aimed to evaluate the predictive value of serum hyaluronate for the presence of extensive liver fibrosis and inflammation.	16221307
Inflammation, Fibrosis Assessment, Complete atrioventricular block	Altered Intercellular Communication	In patients with CHB serum hyaluronate had the most significant correlation and predictive values for the liver fibrosis and inflammation comparing to the other variables.	16221307
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Serum hyaluronate was the best predictor of extensive liver fibrosis and inflammation and it could discriminate subgroups of patients with chronic hepatitis B.	16221307
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Patients with ulcerative colitis (UC) may develop inflammation in the distal ileum thought to be due to "backwash" of cecal contents ("backwash ileitis").	16224214
Inflammation, Villous atrophy, neutrophilic, Cryptitis, Lobular Endocervical Glandular Hyperplasia, Ear Inflammation	Altered Intercellular Communication	Ileal changes included villous atrophy and crypt regeneration without increased inflammation (N = 3), increased neutrophilic and mononuclear inflammation in the lamina propria (N = 6), patchy cryptitis and crypt abscesses (N = 21) and focal superficial surface erosions (N = 4), some with pyloric metaplasia (N = 2 of 4).	16224214
Inflammation, Dysplasia, Complication Aspects, Carcinoma, Ulcerative Colitis, Villous atrophy	Altered Intercellular Communication	Ileal changes in UC are not uncommon (prevalence, 17%), are generally mild in nature (villous atrophy, increased inflammation, scattered crypt abscesses), and are not associated with an increased rate of ileo-anal pouch complications, dysplasia, or carcinoma.	16224214
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The severity of the cancer associated catabolism as well as the inflammation status affect serum TTR and RBP levels.	16225703
methyldopa, Inflammation, Atherosclerosis	Altered Intercellular Communication	Elevated CRP and homocysteine levels are associated with AMD and implicate the role of chronic inflammation and atherosclerosis.	16225921
Inflammation, Iritis	Altered Intercellular Communication	Iritis manifesting as an acute self limited inflammation was the most common adverse event, occurred in a dose response fashion, but was not noted to result in a serious adverse event in any hyaluronidase treated eye.	16226510
Inflammation, Paralytic rabies	Altered Intercellular Communication	Intense inflammation of the spinal nerve roots was observed more in paralytic rabies patients.	16226769
Pain Distress Question, Inflammation	Altered Intercellular Communication	Clinical assessment (pain, inflammation, pigmentation) and ultrasound examination (diameter of the lumen and length of sclerosed vein) were carried out at 15, 30, 90, and 365 days.	16226901
Sclerosis, Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain, signs of inflammation, and pigmentation appeared more often with foam sclerosis, with significant difference.	16226901
Inflammation, Atherosclerosis	Altered Intercellular Communication	The absence of an elevation in E-selectin in this study may be due to its short half-life, and casts doubt on its value as a marker of inflammation in atherosclerosis.	16226905
Inflammation, Heart failure	Altered Intercellular Communication	Inflammation and perturbation of the l-carnitine system in heart failure.	16227137
Conjunctivochalasis, Inflammation	Altered Intercellular Communication	Also, the association of inflammation with conjunctivochalasis is examined.	16227820
Conjunctivitis	Altered Intercellular Communication	It may also be suggested that the conjunctivochalasis has a negligible association with conjunctival inflammation.	16227820
Inflammation, Keratitis, Abnormally opaque structure (morphologic abnormality)	Altered Intercellular Communication	We surmise that epithelial inflammation associated with Thygeson epithelial keratitis may play a role in dissolving the honeycomb opacities.	16227859
Inflammation	Altered Intercellular Communication	Chronic inflammation has a pathological role in many common diseases and is influenced by both genetic and environmental factors.	16227999
Inflammation	Altered Intercellular Communication	These results provide a direct mechanistic link between SEPS1 and the production of inflammatory cytokines and suggest that SEPS1 has a role in mediating inflammation.	16227999
allergic inflammation	Altered Intercellular Communication	The pathogenesis of the disease is unclear but considered as allergic inflammation.	16229364
Chorioretinitis, Pain Distress Question, Complication Aspects, Chorioretinal scar, Vitreous inflammatory cells, Retinal Vasculitis, Retinal Hemorrhage, Optic Neuritis	Altered Intercellular Communication	Patients with severe disease may experience ocular complications that include pain, vitreous inflammation, nonrelapsing chorioretinitis, retinal vasculitis, chorioretinal scarring, optic neuritis, and retinal hemorrhages.	16230277
Chorioretinitis	Altered Intercellular Communication	Many ocular inflammatory conditions with an associated underlying systemic cause often present with chorioretinitis.	16230277
Chronicity, Inflammation, Demyelination, Diffuse Axonal Injury	Altered Intercellular Communication	With chronicity, diffuse inflammation accumulates throughout the whole brain, and is associated with slowly progressive axonal injury in the NAWM and cortical demyelination.	16230320
Inflammation, Ductal Carcinoma	Altered Intercellular Communication	In addition, a very dense stromal inflammation was observed around these ducts, suggesting an invasive ductal carcinoma with predominant intraductal proliferation.	16230949
Alzheimers Disease	Altered Intercellular Communication	3alpha,5alpha-THP: a potential plasma neurosteroid biomarker in Alzheimer's disease and perhaps non-Alzheimer's dementia.	16231167
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Recent literature suggests that neurosteroid metabolism may be altered in Alzheimer's disease (AD).	16231167
Celiac Disease, Enteritis	Altered Intercellular Communication	Coeliac disease, a chronic small intestinal inflammation driven by HLA-DQ2 restricted mucosal T cells that are specific for ingested wheat gluten peptides, is in many ways ideal for this purpose.	16232221
Ichthyosis Bullosa of Siemens, Acute inflammation	Altered Intercellular Communication	With a cutoff level of 250 ppb, NO had a sensitivity of 95% and a specificity of 91% in discriminating between active bowel inflammation and IBS.	16234006
Inflammatory Bowel Diseases, Ichthyosis Bullosa of Siemens, Acute inflammation	Altered Intercellular Communication	Rectal NO is a minimally invasive and rapid tool for discriminating between active bowel inflammation and IBS and a possibly useful add-on for monitoring patients with IBD.	16234006
Airway structure, ARCN1 gene, Asthma	Altered Intercellular Communication	SP may be involved in the airway inflammation process in COPD and asthma.	16234120
Inflammation	Altered Intercellular Communication	Orbital CT revealed left-sided preseptal and postseptal inflammation, along with marked thickening of the left superior ophthalmic vein.	16234708
Inflammation	Altered Intercellular Communication	Histopathologic examination demonstrated a typical picture of lipogranulomatous inflammation.	16234711
Inflammation	Altered Intercellular Communication	Chronic inflammation from polycarbonate motility peg inhibits osteogenesis in a human hydroxyapatite orbital implant.	16234714
Inflammation, Pain Distress Question	Altered Intercellular Communication	The histologic findings of a pegged hydroxyapatite orbital implant removed due to chronic inflammation and pain are described.	16234714
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	This disorder was recently described; it is characterised by a disorder in the pancreas that is indistinguishable from malignancy by imaging techniques and that is followed by a sclerosing inflammation of the bile ducts.	16235802
Inflammation, Hyperhomocysteinemia, Heart failure, Endothelial dysfunction	Altered Intercellular Communication	We have previously shown that hyperhomocysteinaemia is common in elderly heart failure patients, and is associated with endothelial dysfunction, impaired vasodilatory capacity and a low-grade inflammation.	16236143
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Inflammation, complement activation and endothelial function in stable and unstable coronary artery disease.	16236275
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Apart from traditional risk factors complement activation and inflammation may trigger and sustain endothelial dysfunction.	16236275
Inflammation	Altered Intercellular Communication	We conclude that both hs-CRP, a marker of inflammation and C3a, a marker of complement activation are elevated in patients with UAP, but not in patients with SAP.	16236275
Inflammation, Myositis, CTCAE 5.0	Altered Intercellular Communication	Focal myositis constitutes an original and rare pathological entity, characterized by a localized inflammation within skeletal muscle, presenting as a soft tissue painful tumefaction.	16236388
ARCN1 gene, Inflammation, Respiratory physiology	Altered Intercellular Communication	Airway and systemic inflammation and decline in lung function in patients with COPD.	16236847
ARCN1 gene, Inflammation	Altered Intercellular Communication	Patients with COPD experience lower airway and systemic inflammation, and an accelerated decline in FEV1.	16236847
Gastric Xanthoma, Inflammation, Helicobacter pylori, Gastritis	Altered Intercellular Communication	Gastric xanthoma has been associated with helicobacter pylori and chronic gastritis by many authors, some authors think the inflammation gives rise to them.	16237471
Inflammation, Observation Method - Coagulation, Coronary Artery Disease	Altered Intercellular Communication	Influence of prolonged dalteparin treatment on coagulation, fibrinolysis and inflammation in unstable coronary artery disease.	16238677
allergic inflammation	Altered Intercellular Communication	The relationship between HRQL and either allergen exposure or allergic inflammation has not been previously assessed.	16238788
Airway structure	Altered Intercellular Communication	The PADQLQ score was also found to be significantly associated with airway inflammation as measured by FENO (regression coefficient 0.410, 95% CI 0.175-0.646, P=0.001).	16238788
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	High-grade inflammation at the invasive margin in Dukes' stage A and B cancers (pT1-2N0 and pT3N0, respectively) was associated with better 5-year-survival (87.6%) than low-grade inflammation (47.0%).	16239109
Juvenile Neuronal Ceroid Lipofuscinosis	Altered Intercellular Communication	High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease.	16239221
Inflammation, Ear Diseases	Altered Intercellular Communication	The current study suggests that there may be no universal upregulation of chemokines in CHD-associated inflammation but different upregulation of IP-10 and IL-8 versus downregulation of RANTES; there was no clear disease association for MCP-1, MIP-1alpha, or eotaxin.	16239601
Occluded, Vasculitis, CTCAE, Interstitial inflammation	Altered Intercellular Communication	However, the biopsy specimen showed many collapsed glomeruli and interstitial inflammation, indicating the presence of occlusive lesions, such as vasculitis in larger arteries.	16240903
Inflammation, Specimen Source Codes - Abscess, Mycoses, Granuloma	Altered Intercellular Communication	In most tissues the features were those of active chronic inflammation, with or without abscess or granuloma formation, often associated with fungal infection.	16241999
Inflammation, Chronic granulomatous disease, Granuloma	Altered Intercellular Communication	Chronic granulomatous disease may present to histopathologists in a wide range of tissue specimens most often demonstrating features of active chronic inflammation with or without granuloma formation.	16241999
Inflammation, Liver Abscess	Altered Intercellular Communication	In addition, diffuse granulomatous inflammation of the lung and hepatic abscess formation should be regarded as suggestive of the diagnosis.	16241999
Inflammation, Orocutaneous fistula	Altered Intercellular Communication	Unique pericoronal orocutaneous fistula: sequelae of chronic subclinical inflammation.	16243187
Inflammation, AHR wt Allele, Exacerbation	Altered Intercellular Communication	The protection against exacerbations may be attributed to better control of inflammation, AHR and lung function parameters achieved with salmeterol and FP in combination, compared with either treatment alone.	16243498
Inflammation, Necrosis	Altered Intercellular Communication	It is characterized by progressive inflammation and extensive necrosis of subcutaneous tissue involving the fascia and other adjacent tissues.	16243570
Airway structure, Asthma, Bronchiectasis	Altered Intercellular Communication	Increased production of nitric oxide (NO) by the lower respiratory tract is viewed as a marker of airway inflammation in asthma and bronchiectasis.	16244094
Airway structure, Sarcoidosis	Altered Intercellular Communication	As sarcoidosis is characterised by granulomatous airway inflammation, we hypothesised that exhaled NO levels might be raised in sarcoidosis and correlate with the morphological extent and functional severity of disease.	16244094
Inflammation, Gastritis, Atrophic	Altered Intercellular Communication	Atrophic gastritis is associated with increased sucrose permeability related to chronic inflammation.	16244483
Inflammation, Atrophic	Altered Intercellular Communication	Sucrose excretion was positively related to the degree of chronic inflammation (median fraction excreted: mild inflammation 0.06%, moderate inflammation 0.08%, severe inflammation 0.18%; p = 0.04) rather than to the degree of atrophy in the gastric mucosa.	16244483
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	However, in multivariate analysis, including intestinal metaplasia, only the degree of inflammation was positively related to sucrose excretion.	16244483
Inflammation, Atrophic	Altered Intercellular Communication	This leakage seems to be related to the degree of inflammation rather than the degree of atrophy.	16244483
Inflammation, niobium	Altered Intercellular Communication	It may suggest NB as the part of systemic inflammation.	16245421
Inflammation, Disease	Altered Intercellular Communication	Increased concentrations in CSF in both diseases indicate intrameningeal activity of lymphocytes and may be a useful marker of inflammation.	16245421
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The inflammation of the lungs in chronic obstructive pulmonary disease (COPD) is characterised by increased numbers of macrophages, neutrophils and T-cells.	16246539
Inflammation, Anemia	Altered Intercellular Communication	Adjustment for causes and consequences of anemia (renal function, inflammation, or frailty) did not reduce associations.	16246985
Inflammation, Ductal Breast Carcinoma, Neoplasms	Altered Intercellular Communication	Among ductal adenocarcinomas, five (71.4%) of seven tumors for which the size of the hypoechoic area was unchanged on contrast-enhanced sonography had clear tumor margins with no infiltration or inflammation in the margin.	16247133
Inflammation, Neoplasms	Altered Intercellular Communication	In contrast, all tumors for which the size of the hypoechoic area was reduced on contrast-enhanced sonography had unclear tumor margins with infiltration of cancerous cells and inflammation.	16247133
Granulomatous inflammation, Thyroid carcinoma	Altered Intercellular Communication	The purpose of this report is to describe the imaging appearance of granulomatous inflammation in the neck presenting as a late complication in patients who have undergone thyroidectomy for differentiated thyroid carcinoma.	16247162
Granulomatous inflammation, Thyroid carcinoma	Altered Intercellular Communication	Granulomatous inflammation can occur as a palpable mass in the operative bed of asymptomatic patients who have undergone thyroidectomy for thyroid carcinoma.	16247162
Inflammation, Congenital MeSH qualifier	Altered Intercellular Communication	Some webs are thought to be congenital, whereas others occur in the presence of chronic inflammation, suggesting a pathogenic relationship.	16247276
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	In right-sided location of inflammation clinical picture looks like acute appendicitis.	16247385
Inflammation, Perforation (observation), Colon structure (body structure), Peritonitis	Altered Intercellular Communication	In some patients mainly in left-sided location of the inflammation the disease looks like renal colic, perforation of colon or peritonitis.	16247385
Inflammation, Necrosis, Destruction (action)	Altered Intercellular Communication	In 8 of them necrosis was revealed, in 7 -- phlegmonous inflammation of one OP, in 2 -- inflammatory infiltration without destruction.	16247385
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	Laboratory tests revealed inflammation, negative rheumatoid factor, and positive B7 human leukocyte antigen typing.	16247587
Inflammation, Rasmussen Syndrome	Altered Intercellular Communication	Rasmussen encephalitis (RE) is connected with chronic inflammation and damage of one hemisphere.	16247619
Uremic pruritus	Altered Intercellular Communication	The role of micro-inflammation in the pathogenesis of uraemic pruritus in haemodialysis patients.	16249205
HD Term Type, Inflammation	Altered Intercellular Communication	These results point to a central role of inflammation in the pathogenesis of UP in HD patients.	16249205
Inflammation, Atherosclerosis	Altered Intercellular Communication	Resistin may be associated with inflammation and atherosclerosis in humans; however, the role of resistin in human disease remains controversial.	16249281
Inflammation	Altered Intercellular Communication	By contrast, the levels of both TGFbeta2 and CXCL12 decreased in idiopathic uveitis AqH with increasing inflammation.	16249505
Inflammation	Altered Intercellular Communication	Risk factors for local inflammation/infection were postoperative monitoring in intensive care, catheter duration greater than 48 h, male sex, and absence of antibiotic prophylaxis.	16249678
Myocarditis	Altered Intercellular Communication	Detection of pericardial inflammation with late-enhancement cardiac magnetic resonance imaging: initial results.	16249864
Myocarditis	Altered Intercellular Communication	To examine the value of late-enhancement cardiac magnetic resonance imaging (MRI) for detection of pericardial inflammation.	16249864
Myocarditis	Altered Intercellular Communication	Sensitivity and specificity for late-enhancement MRI detection of pericardial inflammation was of 100%.	16249864
Disorder of pericardium, Myocarditis	Altered Intercellular Communication	These findings demonstrate that MRI late enhancement can be used to visualize pericardial inflammation in patients with clinical suspicion of pericardial disease.	16249864
Inflammation	Altered Intercellular Communication	We speculate that inflammation or a recapitulation of developmental signals may be components in the pathogenesis of these lesions.	16253025
Inflammation, "Alzheimers Disease", Cell body of neuron, Data types - Address	Altered Intercellular Communication	Inflammation, insoluble protein deposition and neuronal cell loss are important features of the Alzheimer's disease (AD) brain.	16253391
Inflammation, Data types - Address	Altered Intercellular Communication	This study indicates a potential role for pro-inflammatory S100A9 and S100A12 in pathogenesis caused by inflammation and protein complex formation in AD.	16253391
Inflammation, Anemia	Altered Intercellular Communication	Is hepcidin a link between anemia, inflammation and liver function in hemodialyzed patients?	16254410
Inflammation, Hypoxia, Anemia	Altered Intercellular Communication	Hepcidin synthesis in hepatocytes is modulated in response to anemia, hypoxia or inflammation.	16254410
Inflammation, hepcidin	Altered Intercellular Communication	Low-grade inflammation, frequently found in hemodialyzed patients, might also contribute to elevated hepcidin concentration.	16254410
Inflammation, hepcidin, Anemia, Kidney Diseases	Altered Intercellular Communication	Hypothesis that hepcidin might link anemia, inflammation and liver function in kidney disease should be further evaluated.	16254410
Refractory anemias, Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	Both established CV risk factors and manifestations of RA inflammation contribute significantly to carotid atherosclerosis in RA, and may modify one another's effects.	16255018
Inflammation, Arthritis, Psoriatic, Crohn Disease	Altered Intercellular Communication	Evidence for common genetic control in pathways of inflammation for Crohn's disease and psoriatic arthritis.	16255050
PROS1 gene, Crohn Disease, Inflammation	Altered Intercellular Communication	The OCTN haplotype previously associated with Crohn's disease is also associated with PsA, suggesting that these 2 diseases may share some common genetic control in pathways of inflammation.	16255050
Inflammation	Altered Intercellular Communication	Laparoscopic appendectomy can be performed practically at any form of appendix inflammation.	16255538
Inflammation, Megaesophagus	Altered Intercellular Communication	Comparative study of the presence of Trypanosoma cruzi kDNA, inflammation and denervation in chagasic patients with and without megaesophagus.	16255821
Rupture, Inflammation, Dental Plaque	Altered Intercellular Communication	Plaque rupture has been associated with plaque morphology, plaque components' properties, inflammation and local stress concentration.	16256124
Inflammation, Spitting	Altered Intercellular Communication	Effect of expectoration on inflammation in induced sputum in alpha-1-antitrypsin deficiency.	16257194
Airway structure, Spitting, Chronic lung disease	Altered Intercellular Communication	It is unclear how chronic expectoration influences airway inflammation in patients with chronic lung disease.	16257194
Inflammation, alpha 1-Antitrypsin Deficiency, Spitting	Altered Intercellular Communication	There were no differences in inflammation in induced sputum samples from healthy control subjects and from AATD deficient patients with normal lung function but without chronic expectoration (P>0.05).	16257194
Inflammation, alpha 1-Antitrypsin Deficiency	Altered Intercellular Communication	Inflammation in induced sputum from AATD patients with airflow obstruction and chronic sputum expectoration was significantly greater than for similar patients who did not expectorate: Interleukin-8 (P<0.01), elastase activity (P=0.01), and protein leakage (P<0.01).	16257194
Airway structure, Spitting, alpha 1-Antitrypsin Deficiency	Altered Intercellular Communication	The presence of spontaneous sputum expectoration in AATD patients with airflow obstruction was associated with increased neutrophilic airway inflammation in induced sputum samples.	16257194
Degenerative polyarthritis, Inflammation, Sclerosis of hand bone, Nasal cartilage loss	Altered Intercellular Communication	Human osteoarthritis (OA) is characterized by cartilage loss, bone sclerosis, osteophyte formation and inflammation of the synovial membrane.	16257278
Inflammation, Fracture	Altered Intercellular Communication	Careful diagnostic agreement between PET and CT/MRI for positive but benign lesions, such as inflammation and bone fracture, remains important.	16257440
Inflammation	Altered Intercellular Communication	Inflammation may play an important role in the development of AS.	16257843
Inflammation	Altered Intercellular Communication	Inflammation may play a role in changes in peritoneal function.	16257844
Inflammation	Altered Intercellular Communication	There were no major changes in dialysis adequacy or membrane characteristics during the follow-up period, but increased IL-6 in dialysate may reflect peritoneal inflammation, which may lead to long-term alterations in the peritoneal membrane.	16257844
Inflammation, Pain Distress Question	Altered Intercellular Communication	Chronic inflammation and pain inside the mandibular jaw and a 10-year forgotten amalgam filling in an alveolar cavity of an extracted molar tooth.	16257867
Inflammation, Chronic pain	Altered Intercellular Communication	The authors assume that the chronic pain results from a forgotten amalgam filling inside an alveole after extraction of a molar tooth, causing a chronic inflammation by resolving mercury and other toxic elements out of the metallic artifact.	16257867
Inflammation, Hemorrhage, Necrosis	Altered Intercellular Communication	Paraffin-embedded tissue sections from the popliteal fossa region obtained at autopsy showed hemorrhage, necrosis, and mild inflammation by hematoxylin and eosin staining.	16258164
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	To evaluate the presence and immunohistochemical characteristics of subchondral bone marrow inflammatory infiltrate in rheumatoid arthritis (RA) and to determine the in situ relationship between marrow inflammation and osteoclast recruitment.	16258900
Inflammation	Altered Intercellular Communication	Bone marrow samples showing a higher degree of inflammation were characterized by a significantly increased number of osteoclasts adherent to the subchondral bone.	16258900
Muscle Rigidity, Inflammation, Pain Distress Question, Leukocytosis, Fever, CTCAE, Periumbilical pain, Anorexia, Sore to touch	Altered Intercellular Communication	The severity of the inflammation correlated significantly with periumbilical pain, pain migrating to right lower quadrant, loss of appetite, fever, rebound tenderness, local rigidity, polymorphonuclear predominance on deferential, polymorhonucleosis and leukocytosis.	16259168
Inflammation	Altered Intercellular Communication	Patients with a long duration of symptoms had milder forms of inflammation and increased percentage of unanticipated abdominal conditions.	16259168
Stomach Diseases, Inflammatory Bowel Diseases, Dysplasia, Adenocarcinoma, Dysplasia of colon, Colonic Polyps	Altered Intercellular Communication	The results were: (1) the positivity of TRPV1 receptor and CGRP was detected, and weak participation of SP was detected in patients with different gastric diseases; (2) the presence of TRPV1, CGRP and SP could be detected in chronic inflammation of bowel disease; (3) SP could not detected in patients with colon polyps, dysplasia and adenocarcinoma; (4) the presence of TRPV1 and CGRP was proved in colon dysplasia and adenocarcinoma.	16259736
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Pulse pressure (PP) and inflammation are important predictors of cardiovascular disease (CVD), even in the normotensive.	16260427
Inflammation, Obesity, Atherosclerosis	Altered Intercellular Communication	Inflammation in adipose tissue may link obesity to insulin resistance and atherosclerosis.	16261187
Inflammation	Altered Intercellular Communication	ALOX5AP is present in adipose tissue, where its expression is associated with body weight and HOMA(IR), and may provide a link between adipose tissue, inflammation and insulin resistance.	16261187
Immunocompromised Host	Altered Intercellular Communication	Inflammation of the biliary tract or pancreas by CMV has been commonly reported as a complication in immunocompromised patients.	16261436
Inflammation	Altered Intercellular Communication	A decreasing trend of C-reactive protein, a marker for inflammation, was also observed in those subjects who presented with elevated C-reactive protein.	16261517
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Histological examination with Grocott staining and periodic acid-Schiff diastase revealed fungal spores and hyphae with chronic granulomatous inflammation.	16262877
Inflammation, Eosinophilic granulomatosis with polyangiitis, Vasculitis, CTCAE, Necrosis	Altered Intercellular Communication	The association of ANCA positivity with clinical symptoms that indicate inflammation and necrosis of small vessels might characterize a predominantly vasculitic pattern of the Churg-Strauss syndrome.	16263885
Airway structure, ARCN1 gene	Altered Intercellular Communication	Effect of 1-year smoking cessation on airway inflammation in COPD and asymptomatic smokers.	16264044
Airway structure, ARCN1 gene, Inflammation	Altered Intercellular Communication	Its effect on airway inflammation in COPD is unknown, although cross-sectional studies suggest ongoing inflammation in ex-smokers.	16264044
ARCN1 gene, Airway structure	Altered Intercellular Communication	In the 12 candidates with COPD who successfully ceased smoking, airway inflammation persisted in bronchial biopsies, while the number of sputum neutrophils, lymphocytes, interleukin (IL)-8 and eosinophilic-cationic-protein levels significantly increased at 12 months.	16264044
Airway structure, Chronic Obstructive Airway Disease, Tissue damage	Altered Intercellular Communication	The current authors suggest that the observed persistent airway inflammation in patients with chronic obstructive pulmonary disease is related to repair of tissue damage in the airways.	16264044
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide (eNO) has shown good validity for the assessment of airway inflammation in asthmatic children.	16266381
Inflammation, Data types - Address	Altered Intercellular Communication	These studies implicate COX-mediated inflammation as an early and potentially reversible preclinical event; however, the mechanism by which COX activity promotes development of AD has not been determined.	16267225
Inflammation, Necrosis	Altered Intercellular Communication	The presence of necrosis and/or neutrophilic inflammation in tissue samples correlated with culture positivity.	16267410
Inflammation, Joint laxity, Neoplasms, Communicable Diseases, Traumatic injury	Altered Intercellular Communication	Severe or minor repetitive trauma, inflammation, infection, tumors, and congenital ligamentous laxity have been etiologically implicated in scapholunate dissociation.	16267431
Nose Diseases, Inflammation, Multiple polyps	Altered Intercellular Communication	Leukotrienes that mediate bronchoconstriction as well as chemical mediators of inflammation are observed in the nasal disease associated to polyposis.	16268183
Inflammation, Thrombosis, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is a dynamic disease involving lipid metabolism, inflammation and thrombosis.	16268463
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Inflammation is a key factor in the pathogenesis of abdominal aortic aneurysms (AAA).	16268484
Inflammation, Hyperparathyroidism, Primary, Atherosclerosis	Altered Intercellular Communication	Increased plasma N-terminal pro-B-type natriuretic peptide and markers of inflammation related to atherosclerosis in patients with primary hyperparathyroidism.	16268799
Cardiovascular system, Hypothyroidism	Altered Intercellular Communication	Serum biomarkers for cardiovascular inflammation in subclinical hypothyroidism.	16268812
Inflammation	Altered Intercellular Communication	This suggests that cardiac inflammation is not greater in individuals with SCH.	16268812
Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	The role of active inflammation in idiopathic pulmonary fibrosis (IPF) is controversial.	16268914
Multiple Organ Failure, Inflammation, physiopathological	Altered Intercellular Communication	These data implicate lung dysfunction as central to the promotion of pathogenic inflammation and the development of postinjury MOF.	16269305
Carcinoma, Lesion of breast	Altered Intercellular Communication	Of the 57 breast lesions, 39 were invasive carcinoma and 18 were postbiopsy inflammation.	16269595
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a pivotal role in the pathogenesis of atherosclerosis.	16269662
Tissue damage, Inflammation, Hemorrhage, Edema	Altered Intercellular Communication	Histopathology revealed severe tissue damage, caused by intense hemorrhage, interstitial edema and inflammation.	16270128
Airway structure	Altered Intercellular Communication	An anti-inflammatory role for these receptors in airway inflammation has been suggested.	16271155
Nasal Polyps, Rhinitis	Altered Intercellular Communication	The down-regulation of PPARgamma, in nasal polyposis but not in turbinates during symptomatic seasonal rhinitis, suggests that PPARgamma might be of importance in long standing inflammations.	16271155
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	SIL2r should be considered as a novel marker of inflammation leading to coronary artery disease.	16271309
Pneumonitis	Altered Intercellular Communication	Collectively, these findings suggest that fibroblast apoptosis involves two steps, sensitization and induction, and that inadequate pulmonary inflammation in IPF/UIP may favor fibroblast accumulation by reducing sensitization to apoptosis.	16272460
Inflammation, Pain Distress Question, Hyperemia, Eye Infection, Stinging Sensation, Photophobia, Blurred vision, Corneal edema, Lacrimation	Altered Intercellular Communication	Efficacy (anterior chamber (AC) inflammation, conjunctival hyperaemia, corneal and lid oedema, ocular infection, pain, photophobia and tearing) and safety (burning, stinging, blurred vision, intraocular pressure, and visual acuity) were analysed in the operated eye after 1 and 7+/-1 days.	16273088
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	A new fixed combination of dexamethasone and netilmicin was effective and safe in controlling ocular inflammation after cataract surgery.	16273088
Inflammation, Cholecystitis	Altered Intercellular Communication	Ciglitazone inhibits the inflammation of HGBECs in vitro and has potential therapeutic effect on cholecystitis in vivo.	16273626
Inflammation, Nasal Polyps, Allergic	Altered Intercellular Communication	The goal of this work is to evaluate DNA in the direction of gene mutation in the patients with nasal polyps and/or recurring inflammation of the sinuses, and who tested negative for allergic basis of those ailments.	16273864
Inflammation, Nasal Polyps	Altered Intercellular Communication	The patients had symptoms of nasal polyps and recurring inflammation of the sinuses.	16273864
Acute sinusitis	Altered Intercellular Communication	We discovered 1 mutation of delta F508 in a 40-year-old patient, with recurring inflammation of nasal sinuses (described in the case of this patient).	16273864
Inflammation, Nasal Polyps	Altered Intercellular Communication	A wide routine screening in the direction of the mutation of CF may lead to an explanation the reason of the nasal polyps and inflammation of the sinuses.	16273864
Chorioretinitis, Inflammation, Granuloma	Altered Intercellular Communication	Specific granulomatous inflammation in the uveal tract was observed in all eyes and the morphological feature of sympathizing eyes was the spread of an inflammatory process to the retina with the development of the latter's epithelioid-cell granulomas and adhesive chorioretinitis.	16274065
Vitreoretinal Area, Granulomatous inflammation	Altered Intercellular Communication	The authors also discuss the possibility of additional antigenic stimulation accompanied by a progressive autoimmune process in the eye and by the generalization of a granulomatous inflammation, as well as the role of retinal minor lesions in this process as a source of additional autoantigens during repeated vitreoretinal operations.	16274065
Communicable Diseases, Inflammation	Altered Intercellular Communication	No mobility, signs of infection, or inflammation were detected.	16274156
Inflammation, Abnormal breathing	Altered Intercellular Communication	Laboratory data presented signs of inflammation, but no other abnormality such as renal or respiratory dysfunction.	16274697
Inflammation, Observation Method - Coagulation, Traumatic injury	Altered Intercellular Communication	Sympathetic bias promotes inflammation and coagulation, a link likely forged during prehistoric evolution when trauma represented a more significant factor in natural selection.	16274832
Inflammation, Observation Method - Coagulation, physiopathological	Altered Intercellular Communication	In the setting of carotid sensor dysfunction, the resulting inflammation and coagulation can promote acute cardiovascular events.	16274832
Inflammation, Observation Method - Coagulation, Cerebral Ischemia	Altered Intercellular Communication	The ensuing cerebral ischemia can induce further derangement of cerebrovascular autoregulation and upregulate adrenergia, inflammation, and coagulation in a feed-forward manner.	16274832
Inflammation, Observation Method - Coagulation, physiopathological, Atherosclerosis	Altered Intercellular Communication	Inflammation and coagulation can also exacerbate carotid sensor dysfunction by iteratively worsening atherosclerosis.	16274832
Inflammation, Fibrosis Assessment, Granulation finding, Pseudoepitheliomatous hyperplasia	Altered Intercellular Communication	Pathologic examinations revealed various depths and degrees of acute and chronic inflammation, granulation tissue, and fibrosis in the subepithelial stroma, accompanied by pseudoepitheliomatous hyperplasia in these four patients.	16274894
Inflammation, Atherosclerosis	Altered Intercellular Communication	We tested the hypothesis that a combination of measurements of different aspects of atherosclerosis, including burden of atherosclerosis and levels of inflammation, would contain more predictive information than either alone in an outpatient population.	16275181
Inflammation	Altered Intercellular Communication	We measured ankle-brachial index (ABI) and serum markers of inflammation and followed subjects for a mean of 2.25 years.	16275181
Inflammation	Altered Intercellular Communication	Markers of inflammation, including C-reactive protein (3.83 +/- 0.9 vs 2.11 +/- 1.1, p = 0.019), were higher in subjects who had PAD.	16275181
Inflammation	Altered Intercellular Communication	In conclusion, patients who have PAD and increased inflammation are at highest risk for adverse cardiovascular outcomes.	16275181
ARCN1 gene, Inflammation	Altered Intercellular Communication	These data suggest that nitrosative stress, mainly mediated by MPO and neutrophilic inflammation, may contribute to the pathogenesis of severe COPD.	16275371
Sepsis, Inflammation	Altered Intercellular Communication	Mortality in sepsis is believed to be associated with exaggerated inflammatory responses, but recent evidence suggests that poor outcome is associated with reduced inflammation.	16276178
Inflammation, Communicable Diseases, Specimen Type - Fistula, Esophageal Perforation, Empyema, Foreign body in esophagus, Mediastinitis	Altered Intercellular Communication	Retained oesophageal foreign bodies may cause a multitude of problems, including mucosal ulceration, inflammation or infection, and more seriously paraoesophageal or retropharyngeal abscess formation, mediastinitis, empyema, oesophageal perforation and aorta-oesophageal fistula formation.	16276264
Barrett Esophagus, Chronic inflammation	Altered Intercellular Communication	The first case of Barrett's oesophagus with chronic inflammation having predominantly (> 50%) Mott cells, i.e.	16277029
Cystitis, Chronic disease	Altered Intercellular Communication	Increasing incidence, chronicity of this disorder and specific treatment leads to the reinterpretation of the chronic inflammation of the urinary tract diagnosed in the past and to the modification of the treatment of these patients.	16277181
Inflammation, Periodontal Infection, Obesity, Diabetes Mellitus	Altered Intercellular Communication	A proposed model linking inflammation to obesity, diabetes, and periodontal infections.	16277579
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Previously we observed strong and consistent associations between vitamin B6 status and several indicators of inflammation in patients with rheumatoid arthritis.	16277678
Arthritis, Adjuvant-Induced, Inflammation	Altered Intercellular Communication	Adjuvant arthritis was induced in rats for investigating hepatic and muscle contents as well as the urinary excretion of vitamin B6 during acute and chronic inflammation.	16277678
Arthritis, Adjuvant-Induced, Inflammation	Altered Intercellular Communication	Adjuvant arthritis in rats did not affect 4-pyridoxic acid excretion or muscle storage of pyridoxal 5'-phosphate, but it resulted in significantly lower pyridoxal 5'-phosphate levels in circulation and in liver during inflammation.	16277678
Inflammation, Leptospirosis	Altered Intercellular Communication	Infiltrating cell subpopulations showed mainly CD4+ T lymphocytes, with small numbers of CD8+ cytotoxic lymphocytes, CD20+ B lymphocytes, NKT+ cells and S100+ dendritic cells in the sites of inflammation, as compared to normal and leptospirosis liver blocks.	16278000
Presenile dementia, Inflammation, Vascular Diseases	Altered Intercellular Communication	Because both inflammation and vascular disease are associated with dementia, the objective of the present study was to examine the association between Lp-PLA2 and the risk of dementia.	16278861
Granulomatous inflammation, Herpes zoster disease	Altered Intercellular Communication	The occurrence of a granulomatous inflammation following herpes zoster infection is uncommon and its pathogenesis is unclear.	16279222
Hereditary Autoinflammatory Diseases, Urticaria, Arthropathy, Central Nervous System, Infancy, Radiculopathy, Inflammatory disorder	Altered Intercellular Communication	Neonatal-onset multisystem inflammatory disease (NOMID)/chronic infantile neurologic, cutaneous, and articular syndrome is an autoinflammatory disease characterized by urticarial rash, arthropathy, and central nervous system inflammation.	16279571
Neurogenic Inflammation	Altered Intercellular Communication	Cutaneous neurogenic factors associated with photoageing were characterized by a significant increase in the densities of dermal and intraepidermal nerve fibres, a correlation between epidermal innervation and the severity of photodamage, increases in the number of neuropeptidergic sensory nerve fibres in the dermis and in tissue levels of sensory neuropeptides, increases in the content of nerve growth factor, reduced expression of neurokinin receptor 1 by epidermal keratinocytes and by vascular endothelial cells and a tachykinin-specific reduction of cutaneous neurogenic inflammation.	16280017
Pain Distress Question, prostatitis, Ejaculation, Dysuria, Bacteriuria, Pyuria	Altered Intercellular Communication	Patients were categorized based on NIH prostatitis definitions of type I/II-evidence of pyuria and/or bacteriuria on urinalysis or culture, type III-presence of at least 1 of the pain or urinary symptoms in the NIH Chronic Prostatitis Symptom Index (pain in the perineum, testicles, tip of penis, pubic or bladder area, dysuria, ejaculatory pain, incomplete emptying, urinary frequency), type IV-inflammation on prostate biopsy and Other-symptoms other than those listed.	16280832
Refractory anemias, Inflammation	Altered Intercellular Communication	In patients with high activity of RA, CRV decline reflect severity of inflammation.	16281496
Rupture, Inflammation, Dental Plaque	Altered Intercellular Communication	However, risk of plaque rupture, the most common cause of atherosclerosis-related thromboembolism, is dictated by the composition of the plaque, in particular the degree of inflammation.	16282536
Inflammation	Altered Intercellular Communication	A semiquantitative estimate of plaque inflammation was calculated for all of the lesions identified on HRMRI.	16282536
ARCN1 gene, Inflammation, alpha 1-Antitrypsin Deficiency	Altered Intercellular Communication	In a previous study the sputum of severe AATD subjects with airflow obstruction showed a pattern of cellular inflammation similar to COPD patients.	16284217
ARCN1 gene, Inflammation	Altered Intercellular Communication	These findings indicate that PiMZ subjects without airflow obstruction may have an IL-8 related neutrophilic inflammation in the airways, similar to stable COPD patients, suggesting an increased risk of developing pulmonary changes.	16284217
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	A biopsy of the bladder showed inflammation in the submucosa and the finding of vasculitis.	16285624
Inflammation, Obesity	Altered Intercellular Communication	The implication of obesity and central fat on markers of chronic inflammation: The ATTICA study.	16285994
Inflammation, Obesity	Altered Intercellular Communication	We evaluated the association of obesity with various markers of chronic inflammation, in a population-based sample of 3,042 adults.	16285994
Inflammation, Obesity	Altered Intercellular Communication	We observed that all inflammation markers were related to BMI (index for obesity), waist and to waist-to-hip ratio (indices for central fat), in both genders.	16285994
Inflammation	Altered Intercellular Communication	Our results suggest a relationship between central adiposity and inflammation process, irrespective of age and other potential confounders.	16285994
Inflammation, Obesity	Altered Intercellular Communication	This association was more prominent than the relationship between total obesity and inflammation.	16285994
Inflammation	Altered Intercellular Communication	It could be hypothesized that a disproportionate accumulation of visceral fat mass could be partially associated with increased coronary risk, through inflammation process.	16285994
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Histologically, there was a zonal medial necrosis with surrounding chronic inflammation, focal destruction of the media, and fibrosis of the intima and adventitia.	16286041
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	This study confirms the existence of an independent association between hypertension and inflammation in both men and women.	16286174
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Strict weight management and metabolic control were associated with a reduction in HS-CRP levels, and changes in HS-CRP were related to changes in weight, supporting the hypothesis that lifestyle modification reduces inflammation and the risk of CHD.	16286529
Inflammation, AKR1A1 wt Allele, Cardiovascular Diseases	Altered Intercellular Communication	Therefore, our results do not indicate a role of systemic inflammation in ARM beyond what is already present owing to concurrent cardiovascular disease.	16286611
Communicable Diseases, Inflammation, Unspecified visual loss	Altered Intercellular Communication	We noted no surgical complications of ocular or soft tissue damage, infection, inflammation, or visual loss.	16286624
Inflammation	Altered Intercellular Communication	A highly accurate system which could predict the severity and identify the local extent and complications of a serious inflammation, is beneficial for patient outcome.	16286706
Inflammation, Pancreatitis	Altered Intercellular Communication	The computed tomography severity index is a reliable method for staging the severity of acute pancreatitis; moreover, CT has the ability of showing the local extent of the inflammation and the occurrence of local complications.	16286706
Inflammation, Dental Plaque, Periodontal Diseases	Altered Intercellular Communication	Dental plaque formation was associated with a higher prevalence of periodontal diseases (p = 0.01) and periodontal inflammation scores were higher in patients with more reduced CD4-counts (p = 0.03).	16287607
Inflammation, Dental Plaque, Periodontal Diseases	Altered Intercellular Communication	Lack of oral hygiene determined by plaque formation and reduced CD4-counts with pronounced periodontal inflammation can be seen as risk factors for periodontal disease.	16287607
Rheumatoid Arthritis, Trap medical device	Altered Intercellular Communication	The cytokine profile of C33Y TRAPS differs from that of a typical autoimmune inflammatory condition such as rheumatoid arthritis, as only IL-6 and IL-8 were elevated in C33Y TRAPS patients, as distinct from a generalized elevation of pro-inflammatory cytokines.	16287931
Destruction (action), Inflammation, Demyelinating Diseases, Glioblastoma Multiforme Pathway	Altered Intercellular Communication	A spectroscopic analysis of the largest lesion revealed that this lesion showed evidence of inflammation, with cell destruction and replacement, although it was not possible to distinguish between a demyelinating disease and a high grade glioma.	16288423
Aneurysm, Endoleak, Inflammation	Altered Intercellular Communication	AEF after EVAR has been associated with aneurysm growth, endoleak, migration, and aortic inflammation.	16288707
Aneurysm, Endoleak, Inflammation	Altered Intercellular Communication	AEF can occur after endoluminal stent graft (ELG) in the absence of aneurysm growth, endoleak, migration, or inflammation.	16288707
Inflammation, Metabolic Syndrome X, Cardiovascular Diseases, Hypertension, CTCAE, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Stress-induced increases in cytokine secretion among high HOMA-IR men are consistent with the role of inflammation in cardiovascular disease, hypertension, type 2 diabetes as well as the metabolic syndrome and underscore the relevance of negative affect in the etiology of these inflammatory conditions.	16288846
Inflammation, Metabolic Syndrome X, Cardiovascular Diseases, Hypertension, CTCAE, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Stress-induced increases in cytokine secretion among high HOMA-IR men are consistent with the role of inflammation in cardiovascular disease, hypertension, type 2 diabetes as well as the metabolic syndrome and underscore the relevance of negative affect in the etiology of these inflammatory conditions.	16288846
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The presence of metabolic syndrome is associated with a higher degree of inflammation.	16290227
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	We sought to assess whether the higher levels of cardiorespiratory fitness attenuate the levels of inflammation in people with metabolic syndrome.	16290227
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Our findings suggest that in people with metabolic syndrome an increased level of physical fitness might exert its beneficial effect via attenuating inflammation.	16290227
Inflammation, Virus Diseases, Malnutrition	Altered Intercellular Communication	or biological (aging, free radicals, inflammation, nutrient deficiency, bacteria and virus infections, stress, etc.)	16290925
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Measurement of C-reactive protein (CRP), a marker of inflammation, is recommended to improve cardiovascular disease (CVD) risk stratification.	16290958
Inflammation, Arthropathy, Atrophy of testis, Hereditary Diseases, Alkaptonuria	Altered Intercellular Communication	Ochronotic arthropathy is the articular manifestation of alkaptonuria, a rare hereditary metabolic disease that leads to the deposition of homogentisic acid particularly in the joints where it causes articular degeneration and inflammation.	16292242
Inflammation, Observation Method - Coagulation, Coronary heart disease	Altered Intercellular Communication	Air pollution and markers of inflammation and coagulation in patients with coronary heart disease.	16293802
Inflammation	Altered Intercellular Communication	These results suggest that inflammation as well as parts of the coagulation pathway may contribute to the association between particulate air pollution and coronary events.	16293802
Inflammation, Fibrosis Assessment, Primary malignant neoplasm	Altered Intercellular Communication	Tobacco chewing causing chronic inflammation, submucous fibrosis and oral cancer.	16295466
Inflammation, Caseous necrosis, Tuberculosis	Altered Intercellular Communication	The left upper lobe lesion biopsy showed granulomatous inflammation with caseous necrosis consistent with tuberculosis.	16295820
Inflammation, Dermatitis, Dermatologic disorders, Urticaria	Altered Intercellular Communication	Certain skin disorders, such as contact dermatitis and chronic urticaria, are characterized by inflammation involving mast cells and worsen by stress.	16297195
Inflammation, Lymphedema, Lymphadenopathy	Altered Intercellular Communication	None of the patients presented with distal lymphoedema, and the adenopathy was characterized by painless, localized, lymph-node enlargement, without signs of inflammation in the overlying skin.	16297289
Inflammation, Dilated Cardiomyopathy Pathway, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Activated nuclear transcription factor kappaB in patients with myocarditis and dilated cardiomyopathy--relation to inflammation and cardiac function.	16297880
Inflammation	Altered Intercellular Communication	Since NFkappaB is a crucial key transcription factor of inflammation, its prognostic and future therapeutic relevance should be addressed.	16297880
Arterial Stiffness, Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	The relationship between inflammation and arterial stiffness in patients with essential hypertension.	16297996
Deafness, Sudden, Inflammation, Neurologic Signs	Altered Intercellular Communication	Sudden deafness without associated neurological signs and symptoms is typically attributed to a viral inflammation of the labyrinth.	16298797
Inflammation, Congestive heart failure, Chronic heart failure, Coronary Artery Disease, Cardiomyopathy, Familial Idiopathic	Altered Intercellular Communication	Inflammation and matrix degradation may play a pathogenic role in chronic heart failure (CHF), and therefore, we examined whether thalidomide, a drug with potential immunomodulating and matrix-stabilizing properties, could improve left ventricular (LV) function in patients with CHF secondary to idiopathic dilated cardiomyopathy (IDCM) or coronary artery disease (CAD).	16301340
Inflammation, Inflammatory disorder	Altered Intercellular Communication	T cell-regulated neutrophilic inflammation in autoinflammatory diseases.	16301678
Acute Generalized Exanthematous Pustulosis, Drug Allergy	Altered Intercellular Communication	Previous studies of acute generalized exanthematous pustulosis, a peculiar drug hypersensitivity reaction, suggested that CXCL8-producing T cells regulate sterile, polymorphonuclear neutrophil-rich skin inflammations.	16301678
Diabetic Nephropathy, Inflammation, Smoking	Altered Intercellular Communication	Smoking, oxidative stress and inflammation: impact on resting energy expenditure in diabetic nephropathy.	16303055
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation is associated with increased resting energy expenditure (REE) in patients with chronic kidney disease.	16303055
Inflammation, Smoking	Altered Intercellular Communication	Smoking is a common mechanism for generating oxidative stress and inflammation.	16303055
Airway structure	Altered Intercellular Communication	Use of exhaled breath condensate in the study of airway inflammation after hypertonic saline solution challenge.	16304257
Airway structure	Altered Intercellular Communication	Hypertonic saline solution inhalation is suspected to produce airway inflammation.	16304257
Airway structure, Inflammation	Altered Intercellular Communication	These findings suggest that hypertonic saline solution inhalation could cause a low-grade inflammation in airways, and levels of inflammatory markers such as IL-6, TNF-alpha, and pH in EBC may be a useful noninvasive way to assess and monitor airway inflammation.	16304257
ARCN1 gene, Inflammation	Altered Intercellular Communication	Low-grade systemic inflammation and the response to exercise training in patients with advanced COPD.	16304260
ARCN1 gene, Inflammation	Altered Intercellular Communication	Low-grade systemic inflammation may cause a chronic catabolic state that may affect trainability in patients with COPD as has been seen previously in healthy elderly.	16304260
ARCN1 gene, Airway structure	Altered Intercellular Communication	To clarify the role of endogenous H(2)S in the pathogenesis of COPD, we investigated the relation of serum H(2)S level to severity of COPD as defined by lung function and airway inflammation.	16304263
Granulomatous inflammation	Altered Intercellular Communication	This case demonstrates that elevated angiotensin-converting enzyme and granulomatous inflammation can occur in lymphoma.	16304529
Gingivitis, Hemorrhage, Dental Plaque	Altered Intercellular Communication	The results of this clinical trial indicate that when combined with manual or sonic tooth brushing, oral irrigation is an effective alternative to manual tooth brushing and dental floss for reducing bleeding, gingival inflammation, and plaque removal.	16305005
Inflammation, Metabolic Syndrome X, Diabetes Mellitus	Altered Intercellular Communication	There are few data concerning the relationship between diabetes mellitus, the metabolic syndrome and inflammation following elective percutaneous coronary intervention (PCI).	16305070
Pulmonary Infiltrate, Inflammation, Pneumonia	Altered Intercellular Communication	The diagnosis of pneumonia was made according to: clinical presentation, new and persistent pulmonary infiltrates on chest radiography, positive nonspecific parameters of inflammation, and the microbiological confirmation of causative microorganisms.	16305098
Inflammation, Atherosclerosis	Altered Intercellular Communication	Epidemiologic data regarding the role of inflammation in atherosclerosis have been based mainly on Caucasian populations.	16305810
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Miniaturized cardiopulmonary bypass in coronary artery bypass surgery: marginal impact on inflammation and coagulation but loss of safety margins.	16305899
Inflammation	Altered Intercellular Communication	Inflammation and coagulation disturbances are common consequences of cardiopulmonary bypass (CPB).	16305899
Infertility, Chronic inflammation	Altered Intercellular Communication	Transgenic mice expressing p450 aromatase as a model for male infertility associated with chronic inflammation in the testis.	16306085
Infertility, Orchitis	Altered Intercellular Communication	Hence, the aging AROM+ males present with a phenocopy of inflammation-associated infertility in men, providing a model for further studies on the putative link among estrogens, orchitis, and infertility.	16306085
Renal Insufficiency, Inflammation	Altered Intercellular Communication	We aimed to assess whether in coronary artery diseased patients renal function impairment is associated with systemic vascular function, functional parameters of the renin-angiotensin system, or inflammation as potential mediators for cardiovascular risk.	16306429
Renal Insufficiency, Inflammation, Coronary Artery Disease	Altered Intercellular Communication	In coronary artery disease patients, mild renal function impairment is not associated with systemic vasomotor responsiveness, inflammation, or functional systemic parameters of the renin-angiotensin system.	16306429
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Chronic inflammation is common in hypertension and acts as an independent determinant of arterial blood pressure.	16306795
Shock, Inflammation	Altered Intercellular Communication	The results suggest that blockade of LBP at inflammation sites might attenuate LPS-induced circulatory shock.	16307218
Inflammation, Neoplasms	Altered Intercellular Communication	HGF, a potent stimulator of hepatocyte growth, stimulates the motility, invasiveness, proliferation and morphogenesis of epithelium and may be involved in physiologic and pathologic processes such as embryogenesis, wound healing, organ regeneration, inflammation and tumor invasion.	16308260
Inflammation, Fever, CTCAE	Altered Intercellular Communication	"Periodic fever" without fever: two cases of non-febrile TRAPS with mutations in the TNFRSF1A gene presenting with episodes of inflammation or monosymptomatic amyloidosis.	16308343
Inflammation, Malaria, Trap medical device	Altered Intercellular Communication	In typical cases TRAPS begins early in childhood and is characterised by high and remittent fever over a period of 1-4 weeks or longer, accompanied by systemic and local inflammation.	16308343
Inflammation, Fever, CTCAE, Trap medical device	Altered Intercellular Communication	TRAPS associated mutations can induce considerable inflammation that is not necessarily accompanied by fever.	16308343
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Histopathological examination revealed granulomatous inflammation with areas of caseation necrosis.	16308650
Chronic blepharitis, Inflammation, Obstruction	Altered Intercellular Communication	Dysfunction of the meibomian glands with inflammation and obstruction has been suggested to be an important factor in the pathogenesis of chronic blepharitis.	16308822
Inflammation, Meibomian gland dysfunction	Altered Intercellular Communication	In 15 of 19 patients with blepharitis/meibomitis, but not in meibomian gland dysfunction, an intense inflammation was observed in the tarsal conjunctival epithelium and stroma.	16308822
Inflammation, physiopathological, Coronary heart disease	Altered Intercellular Communication	In the present study, we investigated whether acute local inflammation causes vascular dysfunction and influences t-PA release in patients with stable coronary heart disease.	16309383
vascular inflammations, Coronary heart disease	Altered Intercellular Communication	In patients with stable coronary heart disease, plasma fibrinolytic factors correlate with a systemic inflammatory marker and local vascular inflammation directly impairs vasomotor function whilst enhancing endothelial t-PA release.	16309383
vascular inflammations	Altered Intercellular Communication	We suggest that the adverse prognosis associated with elevated plasma t-PA concentrations relates to the underlying causative association with vascular inflammation and injury.	16309383
Gastrointestinal inflammation	Altered Intercellular Communication	Human mucosa/submucosa interactions during intestinal inflammation: involvement of the enteric nervous system in interleukin-8 secretion.	16309465
Clostridium difficile, Gastrointestinal inflammation, Clostridium difficile enteritis	Altered Intercellular Communication	Interleukin-8 (IL-8) is a key chemokine upregulated in various forms of intestinal inflammation, especially those induced by bacteria such as Clostridium difficile (C. difficile).	16309465
melanoma, Inflammation	Altered Intercellular Communication	Gal-3 might play a role in melanoma progression and/or inflammation, and warrants further study.	16309497
Shock, Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	Heat shock protein induction may also have potential for preventing or treating neurodegenerative disorders, controlling inflammation, and possibly even slowing the aging process.	16309849
Airway structure, Sleep Apnea, Obstructive, Weight decreased	Altered Intercellular Communication	This case establishes that obstructive sleep apnea syndrome (OSAS) may be a potential cause of lower airway inflammation and resulting weight loss in the young CF population.	16309963
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Inflammation is a potential mechanism by which low SES may lead to adverse cardiovascular outcomes, but it is not known whether low SES is associated with inflammation in patients who have CHD.	16310431
Inflammation	Altered Intercellular Communication	This observation raises the possibility that inflammation may contribute to the adverse cardiovascular outcomes associated with low SES.	16310431
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	Relation of inflammation to peripheral arterial disease in the national health and nutrition examination survey, 1999-2002.	16310445
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	The relation between inflammation and peripheral arterial disease (PAD) is not well characterized.	16310445
Inflammation, Obesity, diabetic	Altered Intercellular Communication	Associations between inflammation and PAD were similar across gender, obesity, and diabetic subgroups.	16310445
Inflammation	Altered Intercellular Communication	In conclusion, in the general United States adult population, inflammation is independently associated with PAD.	16310445
Chorioretinitis, Communicable Diseases, Acute and chronic inflammation, Intraocular Lymphoma, Endophthalmitis, CTCAE	Altered Intercellular Communication	There were 28 patients (33 eyes) with suspected intraocular lymphoma and 50 patients (51 eyes) with suspected infection, which was subdivided into chronic endogenous endophthalmitis, atypical chorioretinitis, or chronic postoperative inflammation.	16310459
Primary sclerosing cholangitis, Granulomatous disorder, Cholangitis, Disease	Altered Intercellular Communication	Histologic reexamination identified five different benign processes: lymphoplasmacytic sclerosing pancreatitis and cholangitis, primary sclerosing cholangitis, granulomatous disease, nonspecific fibrosis/inflammation, and stone disease.	16310689
Plaque, Atherosclerotic	Altered Intercellular Communication	Atherosclerotic plaque behaviour is influenced by intra-plaque inflammation, matrix turnover, and the lipid core volume.	16311343
Angle Closure Glaucoma, Glaucoma, CTCAE, Malignant glaucoma, Acute inflammation	Altered Intercellular Communication	Predisposing anatomic features in patients with chronic angle-closure glaucoma, associated with sudden anterior chamber decompression and increased postoperative inflammation, may facilitate the development of malignant glaucoma following combined glaucoma implant and phacoemulsification surgery.	16311957
Inflammation, Hematuria, CTCAE, Low-molecular-weight proteinuria, Anemia, Weight decreased, Kidney Failure	Altered Intercellular Communication	We present the case of a 75-year-old female with weight loss, anemia, systemic signs of inflammation, mild renal insufficiency, microscopic hematuria, mixed glomerular and tubular proteinuria, and high titers of PR3-ANCA.	16312267
Granulomatous inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Extensive work-up showed no signs of granulomatous inflammation or other vasculitic organ involvement.	16312267
Inflammation, Atherosclerosis	Altered Intercellular Communication	Recently, platelet activation and the subsequent local inflammation have been implicated in progression of atherosclerosis.	16313909
Inflammation, Atherosclerosis	Altered Intercellular Communication	Several diseases characterized by chronic inflammation and immune activation have been linked to enhanced risk for atherosclerosis.	16314550
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Measures of subcutaneous fat, inflammation, and frank diabetes were related to gingival symptom reports but not to caregiver status.	16314598
Seizures, Alcohol Withdrawal Delirium	Altered Intercellular Communication	Upregulation of glutamatergic neurotransmission resulting from chronic ethanol intoxication may cause a hyperexcitable state during alcohol withdrawal, which may lead to seizures and delirium tremens.	16314883
Inflammation	Altered Intercellular Communication	Pathological studies show severe loss of myelin sparing U-fibers, axonal disruption, and cavitary lesions without inflammation.	16315274
Inflammation	Altered Intercellular Communication	These data support the hypothesis that increased NK cytotoxicity could be a contributing factor in the generation or potentiation of inflammation in patients with an AAA.	16315339
Inflammation, Fibrosis Assessment, Fatty Liver Disease	Altered Intercellular Communication	Liver slides were classified according to 1) presence of NASH; 2) Inflammation and 3) Fibrosis.	16315634
Inflammation, Fatty Liver Disease	Altered Intercellular Communication	NASH pa- tients and those with higher grade of histological inflammation had increment of transaminases and albumin levels.	16315634
Icterus, Inflammation, Anemia	Altered Intercellular Communication	Laboratory findings showed a mild inflammation and anemia on his admission, and biochemical data showed a rise of hepatobiliary enzyme with jaundice.	16315959
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Coronary risk factors and inflammation in patients with coronary artery disease and internal cardioverter defibrillator implants.	16316699
Inflammation, Restenosis	Altered Intercellular Communication	Genetic factors appear to be important in the restenotic process after percutaneous coronary intervention (PCI), as well as in inflammation, a pivotal factor in restenosis.	16319143
Extrinsic allergic alveolitis, Damage, Excitatory Amino Acids	Altered Intercellular Communication	The pathophysiology of extrinsic allergic alveolitis (EAA) involves oxidative lung damage as well as interstitial and alveolar inflammation.	16319337
Inflammation, Cardiovascular Diseases, Carotid Atherosclerosis	Altered Intercellular Communication	There is a positive association between chronic inflammation and the risk of cardiovascular disease, but whether there is an association between C-reactive protein (CRP) and carotid atherosclerosis is controversial.	16319544
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Growing evidence shows that inflammation plays a central role in the pathogenesis of acute myocardial infarction.	16319659
Inflammation, Thrombosis, Tumor necrosis	Altered Intercellular Communication	Among the factors that promote inflammation and arterial thrombosis, one of the most important is the proinflammatory cytokine tumor necrosis factor-alpha.	16319659
Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	Such chronic inflammatory conditions can induce the development of MALT lymphoma.	16320028
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Eicosanoids play a key role in the regulation of inflammation and fibrosis.	16320329
PROS1 gene, Inflammation, Crohn Disease, Asthma, Arthritis, Psoriatic	Altered Intercellular Communication	The inflammation control group comprised 20 patients with psoriatic arthritis (PsA), 9 with asthma, and 10 with Crohn's disease.	16320331
Inflammation, Arthritis	Altered Intercellular Communication	Thirty-one patients with chronic arthritides received a single IA injection of triamcinolone hexacetonide to treat active large-joint inflammation.	16320336
Inflammation, Scleritis	Altered Intercellular Communication	Two patients initially diagnosed and treated for unilateral scleritis were referred for management of persistent inflammation.	16321896
Inflammation, Carcinoma, Stricture of ureter	Altered Intercellular Communication	Nickel-titanium shape-memory alloy net-like stent was used to treat 9 patients with ureteral stricture, 4 males and 5 females, aged 41 (29-63), with the length of ureteral stricture of 1.0-4.0 cm, the etiology being radical operation for rectal carcinoma in 2 cases, chronic inflammation in 3 case, and operation for benign diseases in 4 cases.	16324387
Corneal epithelial defect, Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	Examination under general anesthesia performed 5 days after the onset of eye symptoms showed severe inflammation and ulceration on the lid margin and the tarsal conjunctiva in both eyes, a total corneal epithelial defect in the right eye, and a geographical corneal epithelial defect in the left eye.	16324747
Inflammation, Corneal Ulcer	Altered Intercellular Communication	Amniotic membrane transplantation performed at the acute phase of TEN is highly effective not only in reducing inflammation and preventing scarring in the conjunctival surface, but also in restoring corneal epithelial integrity in eyes with both corneal and conjunctival ulceration.	16324747
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Increased CECs in ACS patients are closely associated with endothelial damage/dysfunction (vWf and FMD), coagulation (TF) and inflammation (IL-6).	16324758
Inflammation, Hyperhomocysteinemia	Altered Intercellular Communication	Hyperhomocysteinemia correlates with insulin resistance and low-grade systemic inflammation in obese prepubertal children.	16324922
Inflammation	Altered Intercellular Communication	Persistent inflammation plays a role in the development of HF, and various inflammatory cytokines predict cardiovascular events in acute coronary syndromes.	16325035
Autoimmune Diseases, Communicable Diseases, Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	The instability of atherosclerotic plaque is partly determined by local factors, but systemic factors such as infection, inflammation, autoimmunity or genes might also be important.	16325289
Inflammation, Electrocardiogram: myocardial infarction (finding), Peripheral Arterial Diseases, Cerebrovascular accident	Altered Intercellular Communication	High-sensitive C-reactive protein (hs-CRP) is a marker of inflammation which has been shown in several prospective studies to independently predict myocardial infarction, stroke and peripheral artery disease.	16325494
Inflammation, Liver damage	Altered Intercellular Communication	Scientific evidence suggests the critical role of temperature in regulating three mechanisms contributing to cellular damage: Oxidative stress, oxygen demand overload and inflammation.	16326025
Inflammation	Altered Intercellular Communication	Oxidative stress, inflammation and cardiovascular mortality in haemodialysis--role of seniority and intravenous ferrotherapy: analysis at 4 years of follow-up.	16326744
Inflammation	Altered Intercellular Communication	No other complication associated with inflammation were present in any patient.	16327951
Inflammation	Altered Intercellular Communication	Radiological investigations were suggestive of ongoing inflammation within the manubriosternal joint.	16328095
Cataract, Acute inflammation	Altered Intercellular Communication	Comparison of the efficacy and safety of two formulations of diclofenac sodium 0.1% eyedrops in controlling postoperative inflammation after cataract surgery.	16329054
Cataract, Acute inflammation	Altered Intercellular Communication	To compare the efficacy and safety of diclofenac sodium 0.1% eyedrops packaged in an Abak multidose container without preservative (Dicloabak) with the reference product, sodium merthiolate-preserved diclofenac sodium 0.1% eyedrops, in controlling postoperative inflammation after cataract surgery.	16329054
Cataract, Inflammation, Traumatic injury	Altered Intercellular Communication	There was no significant relationship between MSCH formation and age, sex, side of the cataract, history of ocular trauma, or inflammation.	16329055
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	Oxidants that play a role in acute and chronic inflammation and are present in the rheumatoid joint (hydroxyl radical, hypochlorous acid, and peroxynitrite) were used for modification of native CII.	16329077
Inflammation, Calgranulin A	Altered Intercellular Communication	The most prominent change in markers of inflammation was a reduction in the different macrophage subsets (CD68, CD163, MRP-8, and MRP-14), but this was not paralleled by a decrease in serum MRP-8/MRP-14.	16329106
Inflammation Mediators, dystrophic	Altered Intercellular Communication	In conclusion, stromal microcalcification is a dystrophic, inflammation-mediated, benign process.	16329545
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Divergent effects of rofecoxib on endothelial function and inflammation in acute coronary syndromes.	16330117
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by chronic airway inflammation.	16330870
Inflammatory abnormality of the eye, Irritation	Altered Intercellular Communication	SNCD appears to be a disorder that occurs predominantly in middle-aged women and may be associated with chronic ocular surface inflammation and/or irritation.	16331034
Microorganism	Altered Intercellular Communication	The postoperative course was complicated by slight override of the graft associated with an associated epithelial defect, but there was no evidence of microbial keratitis or significant anterior chamber inflammation.	16331055
Abnormal inflammatory response, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Abnormal inflammation, platelets and angiogenesis are involved in the pathophysiology of cardiovascular disease (CVD).	16331109
Inflammation, Overweight, Metabolic Syndrome X	Altered Intercellular Communication	Plasma fatty acid composition is associated with the metabolic syndrome and low-grade inflammation in overweight adolescents.	16332649
Inflammation, Infiltration, Neoplasms, Angiomyolipoma, Calcified (qualifier), Carcinoma, Transitional Cell, Renal Cell Carcinoma	Altered Intercellular Communication	In addition, RCCs may demonstrate unusual findings such as infiltrative growth mimicking transitional cell carcinoma, fatty component mimicking angiomyolipoma, severe perinephric infiltration, and extensive calcifications mimicking inflammation or other tumor.	16333698
Inflammation	Altered Intercellular Communication	After ingested microbes, aged neutrophils are less prone to undergo apoptosis favouring chronic inflammation.	16333761
Inflammation	Altered Intercellular Communication	These findings suggest lower chronic inflammation in nonagenarians, via more zinc available, with subsequent long-life survival.	16333761
Inflammation, Fibrosis Assessment, Hepatitis C, Splenomegaly	Altered Intercellular Communication	A recent single-center multivariate analysis of hepatitis C (HCV) patients showed that having any two criteria: 1) ferritin > or =200 microg/l and 2) spider nevi and/or albumin < or = 35 g/l predicted grade 2 or greater histological inflammation; the presence of any two of the following criteria: spider nevi, platelets < or =150 x 109/l, palpable splenomegaly and/or albumin < or =35 g/l predicted stage 2 or greater histological fibrosis.	16334447
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Absence of predictors also predicted a lack of inflammation and fibrosis.	16334447
Inflammation	Altered Intercellular Communication	For inflammation, 5/5 patients with both criteria (LR 15, PPV 100%), and 8/19 patients with no criteria (LR 0.5, NPV 58%) had moderate-severe inflammation on liver biopsy (p=0.036).	16334447
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	This independent multicenter data set has validated our published model which uses simple clinical variables accurately and significantly to predict hepatic fibrosis and inflammation in HCV patients.	16334447
Inflammation, Autoimmune Chronic Hepatitis	Altered Intercellular Communication	Liver biopsy showed features of chronic inflammation and autoimmune hepatitis was diagnosed.	16334539
Autoimmune Chronic Hepatitis, Acute and chronic inflammation	Altered Intercellular Communication	the presence of scleroedematous lesions of the skin accompanying chronic hepatic inflammation enabled us to establish the diagnosis of scleroderma-like lesions in the course of long lasting mild autoimmune hepatitis.	16334539
Chorioretinitis, Fluorescence	Altered Intercellular Communication	Active lesions showed hypofluorescence from the early to the late phase on both fluorescein angiography and indocyanine green angiography, suggesting chorioretinal inflammation.	16334614
Inflammation	Altered Intercellular Communication	These findings suggested inflammation or scarring of the choroid and retinal pigment epithelial injury.	16334614
Adrenal Gland Neoplasms, Malignant Neoplasms	Altered Intercellular Communication	These data suggest that determination of VEGF and sVEGFR concentration in the serum of patients with hormonal inactive adrenal tumors may be applied as an additional marker of malignancy.	16335673
Erythema Nodosum, Gastrointestinal inflammation	Altered Intercellular Communication	Non-specific intestinal inflammation can be a cause of the erythema nodosum in 1-2%.	16335704
T-Cell Lymphoma, Inflammation, Angioimmunoblastic Lymphadenopathy, Peripheral T-Cell Lymphoma	Altered Intercellular Communication	Three patients diagnosed with nodal and/or extranodal (tonsillar) non-Hodgkin's peripheral T-cell lymphoma (PTCL) and one patient with angioimmunoblastic T-cell lymphoma (AILD), developed specific cutaneous involvement showing prominent epithelioid cell and/or granulomatous inflammation.	16335869
Parkinson Disease, Inflammation	Altered Intercellular Communication	Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys.	16336966
Airway structure, Asthma	Altered Intercellular Communication	The control of airway inflammation is crucial for management of asthma.	16337368
Parkinson Disease, Inflammation, palladium	Altered Intercellular Communication	Recent studies suggest that inflammation may play an important role in the pathogenesis of Parkinson's disease (PD).	16337421
Inflammation, Hepatitis	Altered Intercellular Communication	In addition, the degree of gp210 expression in BECs of small bile ducts was positively correlated to that of portal inflammation, interface hepatitis and lobular inflammation in PBC.	16337775
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	These results indicate that the increased expression of gp210 in small bile ducts, which is probably associated with damage to BECs by inflammation, is possibly involved in autoimmune response to gp210 leading to the progression to end-stage hepatic failure in PBC.	16337775
Cessation of life, vascular inflammations, Chronic Kidney Diseases	Altered Intercellular Communication	The interaction of vascular inflammation and chronic kidney disease for the prediction of long-term death after percutaneous coronary intervention.	16338257
Inflammation, Atherosclerosis	Altered Intercellular Communication	Furthermore, they more commonly have elevated serum markers of inflammation, which may be either directly or indirectly associated with a state of accelerated atherosclerosis.	16338257
Cessation of life, Inflammation	Altered Intercellular Communication	We sought to assess the relationship among glomerular filtration rate (GFR), systemic inflammation, and long-term death after PCI.	16338257
Cataract, Inflammation	Altered Intercellular Communication	We report a case of low-grade inflammation that developed in the anterior segment after cataract extraction with intraocular lens (IOL) implantation.	16338578
Ischemia, Inflammation	Altered Intercellular Communication	The presence of ischemia correlates significantly with markers of inflammation.	16340725
Inflammation	Altered Intercellular Communication	Both appear to be manifestations of the same process, in which inflammation plays a determinate role.	16340789
Primary sclerosing cholangitis, Inflammation, Fibrosis Assessment, Liver Cirrhosis	Altered Intercellular Communication	Primary sclerosing cholangitis (PSC) is a chronic cholestatic disorder characterized by progressive inflammation and fibrosis of the biliary tract, evolving to cirrhosis.	16341383
Inflammation, Secondary carcinoma	Altered Intercellular Communication	These indicators will become useful not only as biomarkers to predict the degree of inflammation in the stomach mucosa, but also as surrogate biomarkers to predict the risk of secondary stomach carcinogenesis in the remnant stomach mucosa.	16341482
Steatohepatitis, Fibrosis Assessment, Inflammation, Hepatitis B, Chronic	Altered Intercellular Communication	Noninvasive assessment of liver steatosis, fibrosis and inflammation in chronic hepatitis C virus infection.	16343065
Inflammation, Dermatitis, Atopic, Respiratory Hypersensitivity, IL13 gene, Disease	Altered Intercellular Communication	Asthma, allergic rhinitis and atopic dermatitis are clinical manifestations of a systemic atopic disorder, which is associated with airway hyper-responsiveness and inflammation.	16344268
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Our findings are consistent with the role of chronic inflammation as an aetiologic factor among non-smoking Asian women, and suggest that asthma/atopy is a risk marker for susceptibility to the development of lung cancer.	16344268
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Similarly, although IR and inflammation variables were significantly associated with incident DM when included in multivariate models with NCEP-defined metabolic syndrome (all P<0.01), expanding the definition by adding these variables as components did not significantly alter the predictive ability of the definition under AROC curve criteria (all P>0.05).	16344402
Systemic Inflammatory Response Syndrome, postperfusion syndrome, Pneumonitis	Altered Intercellular Communication	Cardiopulmonary bypass (CPB) causes a systemic inflammatory response syndrome (SIRS), which can progress to an acute lung inflammation known as postperfusion syndrome.	16350379
Hematuria, CTCAE, Abdominal colic, Cystitis, Hydronephrosis	Altered Intercellular Communication	The symptoms aspecificis of presentation are: hematuria, colic type pains, hydronephrosis and bladder inflammation.	16350557
Postobstructive pneumonia, Stenotrophomonas maltophilia Measurement, Nocardia asteroides	Altered Intercellular Communication	Inflammation resulting from this disease had potentiated a postobstructive pneumonia caused by Nocardia asteroides and Stenotrophomonas maltophilia.	16351036
Inflammation	Altered Intercellular Communication	Delayed hyperenhancement on gadolinium-enhanced CMR, which is indicative of active inflammation (e.g.	16353447
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide (eNO) is a marker reflecting airway inflammation.	16354213
Airway structure, Medically Unexplained Symptoms, Asthma	Altered Intercellular Communication	Oral montelukast sodium treatment of these children with mild to moderate asthma effectively improved asthmatic symptoms and suppressed airway inflammation in 1 week, suggesting that this leukotriene antagonist combined with short-acting beta2 agonists may provide effective treatment option in mild to moderate childhood asthma.	16354213
Steatohepatitis, Inflammation	Altered Intercellular Communication	DS improves both hepatic steatosis and its resulting inflammation.	16354521
Inflammation, Compression, Biliary Fistula, Abdominal Cavity	Altered Intercellular Communication	We suppose that chest compression in combination with a sphincter of Oddi (SO) dysfunction forced intraluminal air retrograde through the SO into the biliary tract, since intraabdominal injury as well as former biliary pathology, inflammation, or biliary-enteric fistula were excluded.	16354604
Pancreatic Trypsin Secretory Inhibitor, Kazal, Chronic inflammation	Altered Intercellular Communication	Compared with PRSS1 mRNA levels, SPINK1 mRNA levels were low in normal appearing tissue but markedly increased in samples with chronic inflammation, independent of PRSS1 genotype.	16354799
Pancreatic Trypsin Secretory Inhibitor, Kazal, Inflammation	Altered Intercellular Communication	The marked increase in SPINK1 gene expression with inflammation is consistent with its regulation as an acute phase protein.	16354799
ARCN1 gene, Cessation of life, Inflammation	Altered Intercellular Communication	COPD, the fifth-leading cause of death worldwide, is characterized by chronic inflammation.	16354850
Granuloma, Hematoma, Deformity	Altered Intercellular Communication	The remaining cases included two hematomas, one granuloma, three inflammations, and one malformation.	16355380
Uveitis	Altered Intercellular Communication	No marked difference was observed in patient age, preoperative intraocular pressure, mean ultrasound time, degree of nuclear hardness, and amount of postoperative intraocular inflammation between groups.	16355950
Granuloma, Inflammation, Neoplasms, Specimen Source Codes - Abscess, Specimen Type - Fistula, Varicosity, Hernia	Altered Intercellular Communication	Our patients 3-8 weeks after uneventful elective clean operations (varicose vein, hernia, benign soft tissue tumor) had unexpected tissue reactions (inflammation, granuloma, extrusion, fistula, abscess) in the vicinity of Vicryl, suture material (8 cases with Vicryl, 4 cases with Vicryl plus.	16356867
Inflammation, Thrombophilia, Atherosclerosis	Altered Intercellular Communication	Since D-dimer and fibrinogen are acute phase reactants, these data support the hypothesis that inflammation is more related to atherosclerosis than is hypercoagulation.	16357107
Inflammation	Altered Intercellular Communication	Nuts and seeds are rich in unsaturated fat and other nutrients that may reduce inflammation.	16357111
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Chronic inflammation has been hypothesized to be a risk factor for prostate cancer.	16357190
Dermatomyositis, Inflammation, Paresis, Myositis	Altered Intercellular Communication	Dermatomyositis is an inflammatory myopathy characterized by muscle weakness and inflammation.	16357773
Histiocytosis, Langerhans-Cell, Inflammation	Altered Intercellular Communication	Serum levels of sIL-2R and sCD154 could be useful as indicators of inflammation and sRANKL/OPG ratios as markers of osteolytic activity in LCH patients.	16358318
Nasal Polyps	Altered Intercellular Communication	Inflammation of the mucosa, mainly eosinophilic is probably the most important factor, which leads to the development of nasal polyps.	16358841
Inflammation, Nasal Polyps	Altered Intercellular Communication	To analyze and compare the history data and eosinophilic inflammation parameters in patients with nasal polyps.	16358841
Inflammation, Nasal Polyps	Altered Intercellular Communication	The patient's history and the intensity of eosinophilic inflammation are not similar in all nasal polyposis patients, that support the classification into PP, A and ASA groups.	16358841
Inflammation, Infection	Altered Intercellular Communication	In this case, we observed who re-occurrence of chronic inflammation accompanied by having infections of lower respiratory tract it is necessary to expand diagnosis to find out the reasons of such disease.	16358904
Inflammation, Lyme Disease	Altered Intercellular Communication	Chronic inflammation in Lyme borreliosis may be sustained by aberrant inflammatory response, characterized by Th1 lymphocyte predominance, which in turn may be determined by chemokines synthesized in inflammatory focus.	16358960
Inflammation, Malnutrition, Osteodystrophy	Altered Intercellular Communication	Also some other biochemical parameters of osteodystrophy, inflammation and malnutrition were measured.	16358989
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Low dose rofecoxib, inflammation and prostacyclin synthesis in acute coronary syndromes.	16358997
Dryness (characteristic), Inflammatory abnormality of the eye	Altered Intercellular Communication	These data suggest that ocular surface NGF may play an important role in ocular surface inflammation processes associated with dry eyes.	16360211
Inflammation	Altered Intercellular Communication	This study investigated whether reduced HDLs, concomitantly with the activation of inflammation, are associated with IDC.	16360363
Inflammation	Altered Intercellular Communication	In conclusion, the data here reported on reduced HDLs and increased endothelial inflammatory activation and the linear negative correlation between HDLs and inflammation markers, particularly soluble intercellular adhesion molecule-1, could suggest a role for HDLs in the endothelial-microvascular dysfunction seen in IDC.	16360363
Hyperparathyroidism	Altered Intercellular Communication	Revisiting lithium-associated hyperparathyroidism in the era of intraoperative parathyroid hormone monitoring.	16360387
Inflammation, Liver and Intrahepatic Biliary Tract Carcinoma	Altered Intercellular Communication	There is evidence that chronic inflammation predisposes to biliary tract cancer and that use of non-steroidal anti-inflammatory drugs (NSAIDs) is protective.	16361272
Sarcoma, Epithelioid, Chronic inflammation, Malignant Neoplasms, Palisading granuloma	Altered Intercellular Communication	Epithelioid sarcoma is an uncommon soft tissue malignancy which is often misdiagnosed as necrobiotic granuloma or chronic inflammation.	16361752
Cataract, Hypersensitivity, Orbital Pseudotumor	Altered Intercellular Communication	Allergic reaction to hyaluronidase: a rare cause of orbital inflammation after cataract surgery.	16362314
Inflammation, Fever, CTCAE, Scleritis, polychondritis, Nasal chondritis, Laryngitis, Fatigue	Altered Intercellular Communication	Two years ago a nasal chondritis with characteristic changes of the nasal profil, scleritis, laryngitis and unspecific general symptoms (fever, fatigue, signs of a systemic inflammation) developed and relapsing polychondritis was diagnosed.	16362396
Inflammation, Glycation End Products, Advanced, Single organ dysfunction, Septicemia, Cessation of life	Altered Intercellular Communication	HMGB1 acts on a specific receptor, RAGE (receptor for advanced glycation end-products), and induces prolonged inflammation, organ failure, septicaemia and death.	16363239
Inflammation	Altered Intercellular Communication	Plasma markers of endothelial damage/dysfunction, inflammation and thrombogenesis in relation to TIMI risk stratification in acute coronary syndromes.	16363252
Inflammation, Blood Vessel, Thrombolysis in Myocardial Infarction Flow	Altered Intercellular Communication	TIMI risk score for UA/NSTEMI identifies those patients with more profound vascular insult, inflammation and thrombogenicity that, in the 'high risk' patient group, predicts short-term outcomes, although vascular damage was the more sensitive predictor.	16363252
Takayasu Arteritis, Temporal Arteritis	Altered Intercellular Communication	Inflammation of the arterial wall has been demonstrated by 18 Fluoro-Deoxyglucose PET imaging in patients with Takayasu's and temporal arteritis.	16363284
Inflammation, Impaired cognition, Thrombophilia	Altered Intercellular Communication	They also support the hypothesis that inflammation and hypercoagulability are implicated in the pathophysiology of cognitive dysfunction associated with APAD.	16364935
Inflammation, Neuronal loss in central nervous system	Altered Intercellular Communication	All of these genes could amplify ongoing inflammation, resulting in further neuronal loss.	16365156
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The severity of inflammation and stage of fibrosis on pathologic examination did not correlate with the CT features.	16365570
Inflammation, Primary malignant neoplasm, Ulcerative Colitis	Altered Intercellular Communication	We must submit that this is just a case report and cannot stand for general cancer development in ulcerative colitis, but it may point out the risk factor of chronic inflammation and leads the surgeon to skillful working when building the pouch.	16365680
physiopathological, Cardiovascular Diseases	Altered Intercellular Communication	These results could be considered as evidence that connecting between endotelial dysfunction (inflammation-atherothrombosis) and cardiovascular disease.	16366171
ACSM3 gene, Inflammation, Complication Aspects	Altered Intercellular Communication	The presented data do not prove that WBCs and CRP values have a direct contribution to the pathogenesis of ischemic complications following SAH, but it supports the assertion that inflammation may present a common pathogenic pathway in the development of such complications.	16369143
Inflammation, Takayasu Arteritis, Hypertension, CTCAE	Altered Intercellular Communication	In this report, we present a different clinical expression of Takayasu arteritis in a young man who had hypertension as the sole manifestation of multiple critical arterial involvement with elevated inflammation markers but no other symptoms.	16370157
Inflammation, Diverticulitis	Altered Intercellular Communication	Sonographic features of uncomplicated diverticulitis were a varying appearance of the diverticulum with pericolic inflammation.	16371557
Inflammation, Diverticulitis	Altered Intercellular Communication	Uncomplicated diverticulitis is seen as a diverticulum of variable echogenicity with pericolic inflammation.	16371557
Crohn Disease, Inflammation, Stenosis	Altered Intercellular Communication	Two radiologists analyzed MR images for presence and extent of Crohn disease lesions, presence of strictures or other complications, and degree of local inflammation.	16371574
Crohn Disease, Inflammation	Altered Intercellular Communication	T2-weighted MR can depict Crohn disease lesions and help assess mural and transmural inflammation with the same accuracy as gadolinium-enhanced T1-weighted MR.	16371574
Multiple Organ Failure, Inflammation, Cessation of life, Shock, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Unbalanced inflammation triggered by shock has been linked to multiorgan dysfunction (MOD) and death.	16371736
Inflammation, Systemic Vasculitis, Disease	Altered Intercellular Communication	Vasculitic syndromes are a group of disorders characterized by inflammation of the blood vessels.	16371800
Neoplasm Metastasis, Orbital Pseudotumor, Malignant Neoplasms	Altered Intercellular Communication	When orbital inflammation is detected in an adult female patient, a full medical history must be obtained and physical examination performed, as orbital metastases have been reported to be the initial manifestation of malignancy in 30 to 50% of cases.	16372219
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Irreversible airflow obstruction in Chronic Obstructive Pulmonary Disease (COPD) is thought to result from airway remodelling associated with aberrant inflammation.	16372907
Inflammation, Ventricular arrhythmia, Necrosis, Cardiac Hypertrophy, Myocardial fibrosis	Altered Intercellular Communication	Aldosterone has been shown to cause coronary inflammation, cardiac hypertrophy, myocardial fibrosis, ventricular arrhythmias, and ischemic and necrotic lesions.	16373465
Hyperglycemia, Inflammation, Carotid Atherosclerosis, diabetic	Altered Intercellular Communication	The combination of hyperglycemia and inflammation is associated with an advanced early carotid atherosclerosis progression and an increased risk of new vascular events in diabetic as well as nondiabetic subjects.	16373634
Communicable Diseases, Inflammation	Altered Intercellular Communication	Markers of inflammation and infection influence the outcome of patients with baseline asymptomatic carotid lesions: a 5-year follow-up study.	16373649
Cerebrovascular, Inflammation, Infection	Altered Intercellular Communication	Beyond traditional cardiovascular risk factors, markers of inflammation and infections seem to significantly influence the occurrence of cerebrovascular and cardiovascular events in patients with baseline asymptomatic carotid lesions.	16373649
Inflammation, Chronic sinusitis	Altered Intercellular Communication	IgE levels in chronic rhinosinusitis may reflect a systemic factor in disease pathogenesis, and are probably not related to the amount of local inflammation within the sinuses.	16374024
Inflammation, Gastrointestinal inflammation	Altered Intercellular Communication	Interleukin (IL)-12p70 and IL-23 are key T helper-1 (TH1) cytokines that drive the inflammation seen in numerous models of intestinal inflammation.	16374252
Inflammation, Crohn Disease	Altered Intercellular Communication	In the present study, we sought to determine whether active inflammation in Crohn's disease (CD) is associated with the increased synthesis of both of these cytokines and whether patients treated with an anti-IL-12p40 mAb down-regulate IL-23 as well as IL-12p70 as previous reported.	16374252
Communicable Diseases, Arthritis, Pain Distress Question	Altered Intercellular Communication	In AS patients, infection was independently associated with female gender (OR 1.96, 95%CI 1.47-2.56), a history of significant peripheral joint inflammation (OR 1.55, 95%CI 1.18-2.05), and increasing pain duration (p=0.05).	16374575
Granulomatous inflammation, Cutaneous Small Vessel Vasculitis, Necrotizing	Altered Intercellular Communication	The histology showed a necrotizing and granulomatous inflammation of the prostate with small-vessel vasculitis and eosinophilic infiltrates.	16374738
Inflammation, Dental Plaque	Altered Intercellular Communication	Inflammation, operated by blood, vascular and immune cells interaction, is implicated in plaque disruption and CD40 ligand (CD40L) was identified on activated T cells and platelets.	16376442
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	We sought to investigate the roles of local inflammation in acute myocardial infarction (AMI).	16376442
Inflammation, myocardial injury	Altered Intercellular Communication	In contrast with myocardial injury represented by IL-6 release, acute rise in sCD40L levels with the MMP-9 activation in the coronary circulation may possibly reflect local inflammation with platelet activation and be a novel marker of plaque damage by PCI.	16376442
Pain Distress Question, Inflammation, Hostility	Altered Intercellular Communication	Hostility and pain are related to inflammation in older adults.	16376518
Inflammation	Altered Intercellular Communication	Chronically elevated systemic inflammation has a dramatic impact on health for older individuals.	16376518
Pain Distress Question, Inflammation, Hostility	Altered Intercellular Communication	As stress-related responses, both hostility and pain perception may contribute to inflammation which in turn may maintain negative emotion and pain over time.	16376518
Inflammation, Hostility, Pain Distress Question	Altered Intercellular Communication	These findings suggest that hostility may play a role in a cycle of inflammation among older adults, and that pain may be particularly problematic for those under chronic stress.	16376518
Inflammation, Hostility, Cardiovascular Diseases	Altered Intercellular Communication	Our results also shed light on inflammation as a mechanism underlying the effects of hostility on cardiovascular disease morbidity and mortality.	16376518
Inflammation	Altered Intercellular Communication	Regression of the iris nodules and anterior segment inflammation was also noted.	16376670
Histiocytosis, Langerhans-Cell, Inflammation	Altered Intercellular Communication	The clinician should include LCH in the differential diagnosis when faced with anterior segment inflammation in conjunction with iris nodules.	16376670
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	C-reactive protein (CRP) is a marker of inflammation and predicts outcome in apparently healthy subjects and patients with coronary artery disease.	16377290
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	Systemic inflammation is present in patients with aortic valve stenosis (AS).	16377290
Inflammation	Altered Intercellular Communication	These findings suggest that inflammation may have a pathogenic role in degenerative AS.	16377290
Inflammation	Altered Intercellular Communication	Low-grade inflammation, thrombogenicity, and atherogenic lipid profile in cigarette smokers.	16377917
Inflammation, Atherosclerosis	Altered Intercellular Communication	As there is now increasing evidence that atherosclerosis is an inflammatory condition, the present study investigated whether inflammation exists in smokers.	16377917
Inflammation	Altered Intercellular Communication	The inflammatory markers and lipid profiles were compared among a current-smoker group (210 patients, mean age 61.8 +/- 11.0 years), past-smoker group (115 patients, 67.1 +/- 9.0 years) and never-smoked group (113 patients, 68.2 +/- 10.7 years), all of whom had no apparent signs of inflammation.	16377917
Inflammation, Dyslipidemias, Coronary Artery Disease, Thrombophilia	Altered Intercellular Communication	Low-grade inflammation, atherogenic dyslipidemia, and hypercoagulability are present in smokers compared with those who have never smoked among subjects without apparent inflammation who underwent coronary angiography on suspicion of coronary artery disease.	16377917
Inflammation, Atherosclerosis	Altered Intercellular Communication	As there is now increasing evidence that atherosclerosis is an inflammatory condition, the present study investigated whether inflammation exists in smokers.	16377917
Sjogrens Syndrome", Inflammation, Atrophy of salivary gland	Altered Intercellular Communication	The histology results of the lip and sublingual biopsies, respectively, were: normal tissue (29%, 24%), chronic inflammation (29%, 41%), compatible, but not characteristic for Sjogren (8%, 7%), Sjogren's syndrome (13%, 24%), salivary gland atrophy (13%, 0%) or non-contributive (8%, 0%).	16378222
Mental disorders	Altered Intercellular Communication	Neurosteroids synthesized in the nervous system are potent modulators of synaptic activity and have been implicated in several neuropsychiatric disorders.	16378642
Inflammation	Altered Intercellular Communication	The finding of a significant linear association of cystatin-C and inflammation markers suggests that even small reductions in renal function may be associated with adverse pathophysiologic consequences.	16378798
Central Diabetes Insipidus, Hypothalamo-Hypophyseal System, Panhypopituitarism	Altered Intercellular Communication	Hormonal assessment of hypothalamic-pituitary dysfunction revealed panhypopituitarism with central diabetes insipidus.	16379037
Nerve Degeneration	Altered Intercellular Communication	The excitatory neurotransmitter, glutamate, has been implicated in processes leading to neurodegeneration.	16379581
Inflammation	Altered Intercellular Communication	Results suggest that synovial macrophage-like cells that produce TRAP are an important feature of the inflammation associated with CCL rupture in dogs.	16379649
Amyotrophic Lateral Sclerosis, Inflammation, Hypoxia	Altered Intercellular Communication	Elevated IL-6 and TNF-alpha levels in patients with ALS: inflammation or hypoxia?	16380619
Parkinsonian Disorders	Altered Intercellular Communication	They found evidence of preserved presynaptic nigrostriatal function, suggesting that parkinsonism in the X fragile premutation might be related to postsynaptic dopaminergic changes or different neurotransmitter alterations.	16380622
Hypersensitivity	Altered Intercellular Communication	The localization of tongue may also play important role in diagnosis for systematic, hormonal, and allergic disorders.	16380783
Coinfection, Inflammation, Alcohol abuse, FAM126A gene, Liver Cirrhosis	Altered Intercellular Communication	Predictors of HCC development in cirrhotic liver are older age, male sex, alcohol abuse, exposure to aflatoxin, coinfection with HCV and HDV, continuously active inflammation, and potentially viral genotype.	16381233
Endothelial dysfunction, Thrombosis, Chronic inflammation, Kidney Failure	Altered Intercellular Communication	There are indications that endothelial dysfunction and/or chronic inflammation, which play an important role in atherothrombosis, are present in early stages of renal insufficiency.	16382015
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	This study investigated whether and to which extent endothelial dysfunction and inflammation were related to renal function and contributed to renal function-associated cardiovascular mortality in a population-based cohort (n = 613), aged 50 to 75 yr, that was followed with a median duration of 12.5 yr. During follow-up, 192 individuals died (67 of cardiovascular causes).	16382015
Exophthalmos, Orbital Pseudotumor	Altered Intercellular Communication	Ocular examination revealed a severe proptosis and pronounced down displacement of the right globe without signs of orbital inflammation.	16382563
Inflammation, Lobular Endocervical Glandular Hyperplasia	Altered Intercellular Communication	Histologically, the corpus mucosa displayed in all cases chronic inflammation with focal complete IM and advanced pyloric metaplasia.	16382988
Inflammation, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease patients who are resistant to erythropoietin (EPO) treatment may suffer from malnutrition and/or inflammation.	16384825
Inflammation	Altered Intercellular Communication	Our findings support a clear association between EPO responsiveness and nutritional and inflammation variables in haemodialysis patients; iron deficiency is still a major cause of hypo-responsiveness.	16384825
ACSM3 gene, Inflammation, Hyperbilirubinemia, Multiple Organ Failure	Altered Intercellular Communication	The activity was closely related to hyperbilirubinemia and inflammation signs, and was extremely low in nonsurvivors with SAH and multiorgan failure.	16385234
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The grades of fibrosis, inflammation and fatty deposit were evaluated on liver biopsy.	16385240
Inflammation	Altered Intercellular Communication	Soluble TNFRs in patients with moderate inflammation were increased compared to those of control and patients with mild inflammation.	16385240
Inflammation	Altered Intercellular Communication	Xanthogranulomatous inflammation is an uncommon, though well-recognized entity that has been described in various organs but mostly commonly in the kidney and gallbladder.	16385379
Inflammation, Behcet Syndrome	Altered Intercellular Communication	Vascular endothelial growth factor (VEGF) is important for angiogenesis and inflammation, both of which are codependent and contribute to the pathophysiology of Behcet disease (BD).	16386649
Inflammatory abnormality of the eye	Altered Intercellular Communication	The increased expressions of VEGF have been observed in the active stage and in the ocular inflammation of BD.	16386649
Inflammatory abnormality of the eye	Altered Intercellular Communication	These results indicate that the VEGF gene polymorphisms are not associated with BD in the Korean population, but they may be involved in the development of the ocular inflammation of BD.	16386649
Cataract, Inflammation	Altered Intercellular Communication	Markers of inflammation, vascular endothelial dysfunction, and age-related cataract.	16386984
Cataract, Inflammation	Altered Intercellular Communication	Two serum markers of systemic inflammation and vascular endothelial dysfunction were associated with nuclear cataract.	16386984
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	All these data indicate a strong relationship among inflammation, genetics, CHD, and longevity.	16387839
Inflammation, Infection	Altered Intercellular Communication	We hypothesize that both the decline in old-age mortality and the increase in height were promoted by the reduced burden of infections and inflammation.	16387863
Psychogenic, Dysgeusia	Altered Intercellular Communication	Since there may be connections between BMS, psychogenic changes, hormonal changes and taste abnormalities, we have examined aspects of taste and thyroid function.	16388288
Inflammation, With intensity	Altered Intercellular Communication	Cerebrospinal fluid pleocytosis indicated central nervous system inflammation, and spinal MRI showed weak signal hypointensity in T1, hyperintensity in T2 and DP between C7 and T2, but no contrast enhancement.	16388372
Acute Coronary Syndrome, Periodontal Infection	Altered Intercellular Communication	Inflammation leading to acute coronary syndrome may be triggered by bacteria causing periodontal infection.	16388809
Inflammation	Altered Intercellular Communication	Thickened omentum showed granulomatous inflammation in the fatty tissue, but no metastases were detected.	16389989
Myocarditis, Pericarditis, Constrictive	Altered Intercellular Communication	Assessment of pericardial inflammation in a patient with tuberculous effusive constrictive pericarditis with 18F-2-deoxyglucose positron emission tomography.	16391161
Inflammation	Altered Intercellular Communication	In the Integrilin Reduces Inflammation in Peripheral Vascular Interventions trial (INFLAME), we hypothesized that eptifibatide reduces the acute inflammatory responses following PVI.	16391376
Inflammation, Angina Pectoris	Altered Intercellular Communication	Arterial remodeling correlates positively with serological evidence of inflammation in patients with chronic stable angina pectoris.	16391382
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Positive coronary artery remodeling correlates with serological markers of inflammation in patients with stable coronary artery disease.	16391382
Lymphoid hyperplasia, Lymphoma, Orbital Pseudotumor	Altered Intercellular Communication	Orbital idiopathic inflammation, lymphoid hyperplasia, and lymphoma may all present clinically in the same manner.	16391631
Orbital Pseudotumor	Altered Intercellular Communication	Idiopathic inflammation displayed a predominance of T cells and all lesions expressed polyclonal light chains.	16391631
Inflammation, Lymphoma, Hyperplasia	Altered Intercellular Communication	The differences in the mean percentages of B cells among the orbital lymphoid lesions (inflammation, 35%; hyperplasia, 65.9%; lymphoma, 87.3%) were statistically significant (p < 0.001).	16391631
Lymphoid hyperplasia, Lymphoma, Orbital Pseudotumor	Altered Intercellular Communication	Of the 55 lesions, 11 (20%) were idiopathic chronic inflammations, 22 (40%) were lymphoid hyperplasias and 22 (40%) were lymphomas.	16391631
Inflammation, Edema	Altered Intercellular Communication	This may have important pathological consequences in terms of perpetuating inflammation and edema by inhibiting the removal of macromolecules, cells, and interstitial fluid.	16392126
Tumor necrosis, Inflammation, Lymphoproliferative Disorders	Altered Intercellular Communication	Tumor necrosis factor (TNF)-alpha plays a key role in H. pylori-associated inflammation and appears to be involved in the evolution of lymphoproliferative disorders.	16393214
Inflammation, Graft-vs-Host Disease	Altered Intercellular Communication	Decreased expression of p63 in oral lichen planus and graft-vs.-host disease associated with oral inflammation.	16393253
allergic inflammation, Infection	Altered Intercellular Communication	Recent evidence suggests that allergic inflammation may be inhibited in the presence of chronic and persistent infections, such as that by Mycobacterium tuberculosis (MTB).	16393268
Allergic, allergic inflammation, Chronic infectious disease	Altered Intercellular Communication	These results of inverse association of strong TST reaction and allergic disease symptoms in children from a TB endemic area are in support of the hypotheses that allergic inflammation may be inhibited by chronic infections, such as MTB.	16393268
Inflammation, Pancreatitis, Chronic	Altered Intercellular Communication	The ECM proteoglycan decorin links desmoplasia and inflammation in chronic pancreatitis.	16394277
Inflammation, Pancreatitis, Chronic	Altered Intercellular Communication	Recurrent inflammation in chronic pancreatitis (CP) is not well understood.	16394277
Non-alcoholic Fatty Liver Disease, Hepatic inflammation	Altered Intercellular Communication	In this study, serum adiponectin levels were investigated in patients with NAFLD to determine its possible role on hepatic inflammation and injury.	16394799
Nonalcoholic Steatohepatitis, Inflammation	Altered Intercellular Communication	Non-alcoholic steatohepatitis patients show lower levels of adiponectin with higher grades of inflammation.	16394799
Inflammation, Septic embolus, Thrombosis	Altered Intercellular Communication	The thrombosis is probably related to perivascular inflammation rather than septic embolus.	16395223
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Elevated resistin levels in chronic kidney disease are associated with decreased glomerular filtration rate and inflammation, but not with insulin resistance.	16395259
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We also investigate possible links with inflammation and the insulin resistance present in patients with chronic kidney disease (CKD).	16395259
Inflammation, Fibrosis Assessment, Connective Tissue Diseases	Altered Intercellular Communication	Progressive systemic sclerosis is a connective tissue disease with inflammation and fibrosis.	16395640
Intraocular inflammation, Uveitis, Intermediate, Behcet Syndrome	Altered Intercellular Communication	Intraocular inflammation (uveoretinitis) is one major complication of Behcet's disease (BD) and responds poorly to drug therapy.	16395727
Inflammation, Neurologic Deficits	Altered Intercellular Communication	Evidence of inflammation, imaging features, and neurological impairment at admission appeared to be less severe in SESD, but the difference did not reach statistical significance.	16395756
Inflammation, Atrophic	Altered Intercellular Communication	Most of the Pap smear results were within normal limits (65.8%) or benign (reactive changes or atrophy with inflammation) (25.2%).	16398222
Inflammation, Chronic Kidney Diseases, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Our results show that the FA index is a weak predictor of CHD in CKD stage 2 to 4 patients, and emphasized the role of inflammation in predicting the CHD risk.	16400230
allergic inflammation, IL13 gene	Altered Intercellular Communication	Perennial allergic rhinitis (PAR) is a persistent allergic inflammation of the upper respiratory tract due to year-round allergen exposure.	16400895
malignant disease, Inflammation, Autoimmune Diseases	Altered Intercellular Communication	Of these subjects, we recruited 1541 non-diabetic subjects without chronic or acute inflammation, malignant diseases, autoimmune disorders, elevated serum creatinine levels, and abnormal hepatic function tests.	16401315
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	To examine the relationship of systemic markers of inflammation, endothelial dysfunction, and serum folate level to retinal vessel diameter.	16401789
Inflammation	Altered Intercellular Communication	These data show an association of inflammatory markers with larger retinal venular diameter, suggesting that retinal venular caliber may be a marker of systemic inflammation.	16401789
Inflammation, Low Vision, Neuritis, Optic Atrophy, Hereditary, Leber, MS gene, Optic Neuritis	Altered Intercellular Communication	The absence of inflammation of the optic disc, which could lead to the suspicion of a retrobulbar neuritis, must act as a warning to the physician that he or she is possibly before a case of Leber's optic neuropathy, especially when the loss of vision is still progressing, when there is early bilateral involvement or if there is a family history of optic neuritis or multiple sclerosis.	16402322
Excessive tearing, Nasolacrimal Duct Obstruction, Inflammation	Altered Intercellular Communication	Nasolacrimal duct obstruction, secondary to inflammation of the nasal mucosa, can result in epiphora.	16402646
Inflammation, Congestive heart failure	Altered Intercellular Communication	Increased systemic inflammation and oxidative stress in patients with worsening congestive heart failure: improvement after short-term inotropic support.	16402915
Inflammation	Altered Intercellular Communication	In conclusion, our results demonstrate that patients with decompensated CHF have marked systemic inflammation and increased production of oxygen free radicals.	16402915
Inflammation	Altered Intercellular Communication	Short-term inotropic support improves functional status and reduces indices of inflammation and oxidative stress in patients with decompensated CHF.	16402915
Intraocular inflammation	Altered Intercellular Communication	To assess whether the results of microbial and cytological investigations of vitreous biopsy specimens are useful in the management of patients with intraocular inflammation.	16402953
Inflammatory abnormality of the eye	Altered Intercellular Communication	The clinical diagnosis was correct in 37 of 59 patients (62.7%) with ocular inflammation.	16402953
Inflammation, Neoplasms, Viral retinitis, Retinal Detachment, melanoma, Lymphoma, Idiopathic posterior uveitis, Fungal endophthalmitis, Infectious Endophthalmitis, Carcinoma of lung, Toxoplasmosis	Altered Intercellular Communication	These patients included toxoplasmosis that was thought to be viral retinitis; malignant melanoma thought to be fungal endophthalmitis; chronic inflammation secondary to retinal detachment that was thought to be a neoplasm; three patients with infective endophthalmitis thought to be idiopathic uveitis and a patient with known lung carcinoma thought to have metastases who had lymphoma.	16402953
Communicable Diseases, Inflammatory abnormality of the eye, Malignant Neoplasms	Altered Intercellular Communication	Vitreous biopsy is a safe and useful method for diagnosing and excluding malignancy and infection in patients with ocular inflammation.	16402953
Granulomatous inflammation	Altered Intercellular Communication	Histopathologic examination demonstrated a nodular and diffuse infiltrate in the reticular dermis, which was composed of lymphocytes, macrophages with granulomatous inflammation, and numerous eosinophils.	16403389
Colitis	Altered Intercellular Communication	Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation.	16403786
Colitis	Altered Intercellular Communication	Colon inflammation was induced in mice and rats with 2,4-dinitrobenzene- and 2,4,6-trinitrobenzene sulfonic acids (DNBS and TNBS), respectively.	16403786
Inflammation, Streptococcus anginosus	Altered Intercellular Communication	Histological examination of the lesion was consistent with chronic inflammation and Staphylococcus aureus, Streptococcus anginosus and Escherichia coli were isolated on cultures.	16405485
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Scalp biopsy of the affected frontal hairline revealed peribulbar lymphocytic inflammation, but no evidence of lichenoid inflammation, perifollicular fibrosis or scarring.	16405488
Inflammation	Altered Intercellular Communication	The fractalkine receptor CX3CR1 has been shown to be involved in inflammation and immune response.	16405540
Inflammation	Altered Intercellular Communication	Interleukin-1beta plays an important role in inflammation and gastric physiology.	16405550
Inflammation, Data types - Address	Altered Intercellular Communication	Our data strongly support a major role of PPARgamma in the modulation of amyloid-beta generation by inflammation and suggest that the protective mechanism of NSAIDs in AD involves activation of PPARgamma and decreased BACE1 gene transcription.	16407166
Inflammation, Dysplasia, Hyperplasia, Helicobacter	Altered Intercellular Communication	Histopathologic scores for inflammation (P < 0.01), hyperplasia (P < 0.01), and dysplasia (P < 0.05) were significantly higher in the ileocecocolic (ICC) junction of animals in group C, relative to group A. Dysplastic lesions of various grades were detected in 5 of 11 hamsters in group C. Interestingly, the segment of the bowel that is usually colonized by Helicobacter spp.	16407482
Pancreatic squamous cell carcinoma, Inflammation, Squamous metaplasia, Neoplasms	Altered Intercellular Communication	Although, squamous metaplasia of the ductal columnar cells can be observed during periods of inflammation, squamous cell pancreatic carcinoma is an extremely rare tumour.	16407618
Inflammation, Asthma	Altered Intercellular Communication	In this case study, it was suggested that HFA-BDP may reduce eosinophilic inflammation remained in the peripheral airway, and may be effective in supplementing the activity of PSL which must be taken orally by severe asthmatic patients.	16407676
Inflammation, Demographics Domain, Dyslipidemias, Kidney Diseases, Impaired T cell function, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Dyslipidemia and inflammation may promote renal disease via mechanisms of vascular endothelial cell dysfunction in type II diabetes mellitus (DM).	16408124
Inflammation	Altered Intercellular Communication	The bloody sputum was caused by chronic inflammation of the ACB.	16408470
Inflammation, Meckel Diverticulum, Gangrene, Peritonitis, Disseminated Intravascular Coagulation, Intestinal Obstruction	Altered Intercellular Communication	The data obtained on 19 children aged 3 months to 14 years with urgent abdominal inflammation (gangrenous appendicitis, perforative Meckel's diverticulum, intestinal obstruction complicated by peritonitis) support suggestion about underlying endotoxin aggression in pathogenesis of disseminated intravascular coagulation.	16408661
Bacterial prostatitis, prostatitis	Altered Intercellular Communication	Nonbacterial prostatitis was defined by the evidence of prostatic inflammation but negative cultures of urine and prostatic fluids in men with various genitourinary symptoms.	16409229
Bacterial prostatitis, prostatitis, Premature Ejaculation	Altered Intercellular Communication	Prostatic inflammation was found in 64% and chronic bacterial prostatitis in 52% of the patients with premature ejaculation, respectively, showing statistical significance compared with control subjects (P < 0.05).	16409229
Inflammation, Tuberculosis	Altered Intercellular Communication	Skin and lymph node biopsy showed granulomatous inflammation suggestive of tuberculosis.	16409910
vascular inflammations, Atherosclerotic lesion	Altered Intercellular Communication	Four weeks of treatment with rosiglitazone significantly reduces vascular inflammation in nondiabetic patients, leading to a more stable type of arteriosclerotic lesion.	16410460
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	The role of microglia-mediated inflammation in the progression of Alzheimer's disease (AD) neuropathology remains unclear.	16410654
Somatotropin deficiency, Cardiovascular morbidity, Cardiovascular Diseases	Altered Intercellular Communication	Growth hormone deficiency (GHD) is a risk factor for increased cardiovascular disease, and it has been recently demonstrated that abnormalities in coagulation system might contribute to the increased cardiovascular morbidity and mortality.	16410662
Inflammation	Altered Intercellular Communication	In patients with APCR, it may be more difficult and/or important to control inflammation.	16411113
Myocarditis, Cardiomyopathies	Altered Intercellular Communication	Right ventricular endomyocardial biopsy is the gold standard for detecting active myocardial inflammation in cardiomyopathy as well as rejection after cardiac transplantation.	16412182
Inflammation	Altered Intercellular Communication	There is a controversy regarding whether there is widespread inflammation involving non-culprit lesions, or whether inflammatory involvement is limited to the culprit lesion.	16412851
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation, oxidative stress, and platelet activation are involved in the pathogenesis of type 2 diabetes (T2DM) and its complications.	16412866
Orbital Pseudotumor	Altered Intercellular Communication	Computed tomography showed a similar diffuse orbital inflammation.	16412942
Alzheimers Disease", Loss of neurons	Altered Intercellular Communication	Besides formation of neurofibrillary tangles and neuron loss, the Alzheimer's disease brain is characterized by neuritic plaques consisting of beta-amyloid peptide deposits and impaired neurotransmission.	16413130
Lesion, Blood Clot, Nephritis	Altered Intercellular Communication	Patients with a history of extensive abdominal surgery or prior procedures on the affected kidney, evidence of perirenal inflammation, renal lesions 10 cm or more in diameter, or level I renal vein thrombus were included.	16413330
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	We determined the effect of long-term theophylline treatment on airway inflammation in patients with chronic obstructive pulmonary disease (COPD).	16413994
Tumor necrosis, Lymphoma, Spondylitis	Altered Intercellular Communication	Besides inflammation-lymphoma aetiology, information on risk of lymphoma in ankylosing spondylitis is particularly important as a benchmark in the evaluation of, for example, tumour necrosis factor inhibitors.	16414970
Lymphoma	Altered Intercellular Communication	Several inflammatory conditions are associated with an increased risk of lymphoma.	16414970
Inflammation, MS gene, Nerve Degeneration	Altered Intercellular Communication	Aside acute focal recurrent inflammation and diffuse chronic neurodegeneration, accelerated ageing-related mechanisms may operate in the central nervous system of multiple sclerosis patients.	16415309
Inflammation, Neutrophilia (finding)	Altered Intercellular Communication	Intraperitoneal injection of lactoferrin ameliorates severe albumin extravasation and neutrophilia in LPS-induced inflammation in neonatal rats.	16415506
Inflammation	Altered Intercellular Communication	Lactoferrin (LF) plays various anti-inflammatory roles in inflammation experimentally induced by lipopolysaccharides (LPS).	16415506
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	The histological features of chronic inflammation in primary Sjogren's syndrome may be associated with B cell hyper-reactivity.	16415556
Inflammatory Bowel Diseases, Autoimmune Diseases, Ulcerative Colitis	Altered Intercellular Communication	Sera were collected from 150 patients with IBD (73 with UC and 77 with CD), 31 cases with non-IBD intestinal inflammation, 16 cases with other autoimmune diseases, and 104 healthy controls.	16416183
Inflammation	Altered Intercellular Communication	It is characterized by a chronic, non-specific inflammation of the retroperitoneum, which obstructs retroperitoneal structures.	16417011
Depressive disorder	Altered Intercellular Communication	The female depressive disorders after menopause are associated with their psychosocial conditions but not with their hormonal status.	16417094
Inflammation, Psoriasis	Altered Intercellular Communication	Psoriasis is a chronic and excessive inflammation of the skin and is currently incurable.	16417229
Inflammation, herpesvirus 3, human, Intracranial Hemorrhage, Necrotizing Arteritis	Altered Intercellular Communication	We postulate that direct invasion of VZV caused extensive inflammation of the vessel wall and aggressive tissue penetration resulting in necrotizing angiitis and intracranial haemorrhage.	16417671
Inferior alveolar canal, Inflammation, Neoplasms	Altered Intercellular Communication	Those for inferior alveolar canal involvement were due to MR imaging visualization of the tumor and surrounding inflammation with similar signal intensity.	16418368
Granulomatosis with polyangiitis, Conjunctivitis	Altered Intercellular Communication	Cicatricial conjunctival inflammation with trichiasis as the presenting feature of Wegener granulomatosis.	16418677
Granulomatosis with polyangiitis, Conjunctivitis	Altered Intercellular Communication	Although conjunctival involvement in this condition is rare, the diagnosis of Wegener granulomatosis should be suspected when the conjunctival inflammation is recurrent and not typical of other conjunctival inflammatory conditions.	16418677
Granulomatosis with polyangiitis, Conjunctivitis	Altered Intercellular Communication	Although conjunctival involvement in this condition is rare, the diagnosis of Wegener granulomatosis should be suspected when the conjunctival inflammation is recurrent and not typical of other conjunctival inflammatory conditions.	16418677
Communicable Diseases, Inflammation	Altered Intercellular Communication	There was no evidence of infection or other immune-related causes and the inflammation had a temporal correlation with his dermatological GVHD.	16419427
Inflammation, Postoperative Complications	Altered Intercellular Communication	This resulted in relief of inflammation and reduction of the number of postoperative inflammatory complications.	16419474
Inflammation, Guillain-Barre Syndrome	Altered Intercellular Communication	Sympathetic chain analysis revealed decreased myelinated axons with vacuolar degeneration and patchy inflammation consistent with Guillain-Barre syndrome.	16420295
Inflammation, Cerebral dysfunction	Altered Intercellular Communication	The results suggest that for brain-damaged patients, increased activation of the kynurenine pathway, oxidative stress and raised levels of inflammation continue many years after the original insult, possibly contributing to the continuing cerebral dysfunction in these patients.	16420391
Inflammation, Autoinflammatory disorder, Fever, CTCAE, Tumor necrosis, Trap medical device	Altered Intercellular Communication	Tumour necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) is an autoinflammatory disorder characterized by periodic attacks of fever and inflammation, due to mutations in the gene coding for the TNF type I receptor (TNFRSF1A).	16420550
Inflammation, Thrombosis, Cardiovascular Diseases	Altered Intercellular Communication	Polymorphisms in candidate genes related to lipid metabolism, thrombosis, hemostasis, cell-matrix adhesion, and inflammation have been suggested clinically useful in risk assessment of cardiovascular disease.	16420563
Inflammation, Bacterial Infections	Altered Intercellular Communication	Hypertonic saline was not associated with worsening bacterial infection or inflammation.	16421364
Opacification of Medical Device Material, Uveitis	Altered Intercellular Communication	Surgery-related complications, operating time, intraoperative balanced salt solution (BSS) consumption, postoperative discomfort, postoperative intraocular inflammation, lens opacification, and long-term visual outcome are reported and compared.	16421743
Intraocular inflammation	Altered Intercellular Communication	Postoperative discomfort and intraocular inflammation were significantly reduced in the 25-gauge group.	16421743
Traumatic injury, Uveitis	Altered Intercellular Communication	Operating time is significantly reduced, minimizing surgery-induced trauma, and reducing postoperative intraocular inflammation and the patients' discomfort.	16421743
Inflammation	Altered Intercellular Communication	This case, together with other rare reports, suggests that the presence of inflammation in the biopsy of an affected muscle may predict treatment response.	16421882
Inflammation	Altered Intercellular Communication	Association of impaired glucose tolerance with increased heart rate and subclinical inflammation.	16422126
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation in asthma could be categorized into four inflammatory subtypes based on sputum eosinophil and neutrophil proportions.	16423202
Airway structure, Asthma	Altered Intercellular Communication	These inflammatory subtypes have important implications for the investigation and characterization of airway inflammation in asthma.	16423202
Autoimmune Diseases, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Serum adiponectin in a population sample of 64-year-old women in relation to glucose tolerance, family history of diabetes, autoimmunity, insulin sensitivity, C-peptide, and inflammation.	16423625
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus	Altered Intercellular Communication	In conclusion, serum adiponectin was lowered in women with type 2 diabetes mellitus, and this difference could only be partly explained by insulin resistance, insulin secretion, family history of diabetes, and inflammation.	16423625
Inflammation, Primary malignant neoplasm, Somatic mutation	Altered Intercellular Communication	Potential molecular and physiologic contributors to the frequency of cancer occurrence in older individuals include the accumulation of somatic mutations through defects in genome maintenance, epigenetic gene silencing, oxidative stress, loss of immune surveillance, telomere dysfunction, chronic inflammation, and alterations in tissue microenvironment.	16424011
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Based on its role in inflammation and matrix degradation, we hypothesized a role for osteoprotegerin (OPG), RANK, and RANK ligand (RANKL) in coronary artery disease.	16424351
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	CD4 T cells, through the release of cytokines as well as direct effector functions, have been implicated in promoting inflammation of the atherosclerotic plaque.	16424368
Chronic Obstructive Airway Disease	Altered Intercellular Communication	No currently available treatment is reported to reduce the exaggerated airway wall inflammation of chronic obstructive pulmonary disease.	16424444
Alzheimers Disease", Data types - Address, Nerve Degeneration	Altered Intercellular Communication	Alzheimer's disease (AD) is a devastating neurodegeneration with a characteristic deficit in cholinergic neurotransmission.	16424819
Atrophic, Inflammatory disease of mucous membrane	Altered Intercellular Communication	H pylori eradication may improve gastric mucosal inflammation, atrophy and prevent the progression of IM.	16425426
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Fibrosis is the formation of scar tissue due to injury or long term inflammation.	16425540
Myocarditis, Reperfusion Injury	Altered Intercellular Communication	The effects of pentoxifylline on the myocardial inflammation and ischemia-reperfusion injury during cardiopulmonary bypass.	16426349
Myocarditis	Altered Intercellular Communication	These results show that Ptx may be added into cardioplegic solution to avoid the myocardial inflammation and I/R injury during open heart surgery.	16426349
Cognitive deterioration, Inflammation	Altered Intercellular Communication	Indices of low-grade chronic inflammation correlate with early cognitive deterioration in an elderly Greek population.	16426755
Inflammation, Trauma, Nervous System	Altered Intercellular Communication	Elevated serum levels of adhesion molecules (AM) reflect low-grade chronic inflammation and have been associated with several conditions of neuronal damage.	16426755
Peripheral Vascular Diseases, Communicable Diseases, Chlamydia, Inflammation	Altered Intercellular Communication	Inflammation and Chlamydia pneumoniae infection correlate with the severity of peripheral arterial disease.	16427340
Peripheral Vascular Diseases, Communicable Diseases, Chlamydia, Inflammation	Altered Intercellular Communication	Our aim was to investigate the association of inflammation and Chlamydia pneumoniae infection with the presence and severity of peripheral arterial disease.	16427340
Communicable Diseases, Inflammation, immunoglobulin A, Atherosclerosis	Altered Intercellular Communication	This study supports the hypothesis that inflammation (CRP) and chronic C. pneumoniae infection (IgA seropositivity), have an important role in lower limb atherosclerosis and correlate with the severity of the disease.	16427340
Inflammation, Coronary heart disease	Altered Intercellular Communication	Pulpal inflammation and incidence of coronary heart disease.	16427454
Inflammation, Coronal (qualifier value)	Altered Intercellular Communication	Pulpal inflammation is primarily caused by coronal caries, and leads to root canal therapy (RCT).	16427454
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Chronic inflammation has been associated with various cardiovascular diseases.	16427454
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	The results suggest a possible modest association between pulpal inflammation and CHD.	16427454
Communicable Diseases, Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Following successful revascularisation there was less infection and inflammation with minimal vasculitis.	16427789
Inflammation	Altered Intercellular Communication	Elevated preprocedural systemic markers of inflammation, including white blood cell count, have been associated with adverse clinical outcomes after percutaneous coronary intervention.	16427856
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a disease characterised by inflammation of the peripheral airways involving many inflammatory cells and mediators.	16429233
Pneumonitis	Altered Intercellular Communication	Our results suggest that TNF-alpha is associated with COPD-related phenotypes and the CXCR2 +785 SNP may be important in protecting against pulmonary inflammation.	16429233
Inflammation, Cystitis, Ulcer	Altered Intercellular Communication	Pathologic report of the transurethral resection chips showed polypoid cystitis with some small size arteries occupied by cholesterol needles, associated with inflammation, ulcers and hematic extravasation.	16430035
Inflammation, precancerous lesions, Ischemic, Vasculitis, CTCAE	Altered Intercellular Communication	d-VIN in LS is rare, while p53 staining is common and best explained as an ischaemic stress response due to poor oxygenation, vasculitis and inflammation rather than as a marker of a precancerous lesion in LS.	16430473
Refractory Cytopenia of Childhood, Inflammation, Frontal headache, Hypopituitarism	Altered Intercellular Communication	Among six patients with histologically recognized intense chronic inflammation in the cyst wall, five patients had an RCC of T1 high intensity (P=0.0161), two patients had distinct rim enhancement on MRI (P=0.0060), all patients had frontal headaches (P=0.0130), and four patients had associated hypopituitarism (P=0.0243), none of which improved after surgical intervention.	16430718
Cyst, Chronic inflammation, physiopathological	Altered Intercellular Communication	RCCs of high- and isointensity on T1-weighted images, which contain mucous material within the cyst, may be associated with chronic inflammation that can potentially cause irreversible endocrine dysfunction.	16430718
Inflammation, Renal Cell Carcinoma	Altered Intercellular Communication	In asymptomatic patients with RCCs of these MR intensities, close follow-up with precise endocrinological evaluation and gadolinium-enhanced MRI is necessary to avoid occult progression of the inflammation.	16430718
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide (NO) is an established technique for monitoring airway inflammation.	16431095
Adenocarcinoma, Inflammation	Altered Intercellular Communication	Cytology revealed chronic inflammation in 7 patients, while adenocarcinoma was found in the remaining 4.	16431311
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Abdominal aortic aneurysm (AAA) expansion is characterized by extracellular matrix degradation and widespread inflammation.	16432074
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	However, it is not clear whether systemic markers of inflammation predict cancer.	16432087
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	These data provide new epidemiological evidence of an association between circulating WBC count, a widely available marker of inflammation, and subsequent cancer mortality.	16432087
Inflammation, Sarcoidosis, Clonal Anergy, Granuloma	Altered Intercellular Communication	Sarcoidosis is characterized by extensive local inflammation (granuloma, cytokine secretion) associated with anergy (poor response to antigens in vitro and in vivo).	16432251
Inflammation, Sarcoidosis	Altered Intercellular Communication	Sarcoidosis is therefore associated with a global T reg cell subset amplification whose activity would be insufficient to control local inflammation.	16432251
Encephalomyelitis, Inflammation, Inflammatory disorder	Altered Intercellular Communication	Acute disseminated encephalomyelitis ADEM is an uncommon inflammatory disease of the central nervous system and can be defined strictly as scattered focal or multifocal disseminated inflammation of brain or spinal cord, or both.	16432607
Inflammation, Dental Plaque	Altered Intercellular Communication	Efficacy of chlorhexidine-thymol varnish (Cervitec) against plaque accumulation and gingival inflammation in a geriatric population.	16433641
Inflammation, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	These cases demonstrate an association between myocarditis in KS and severe or worsened inflammation.	16434816
Inflammation, Microcytic hypochromic anemia (disorder)	Altered Intercellular Communication	Serum sTfR and sTfR/ferritin ratio are useful parameters in hypochromic microcytic anaemia to diagnose iron deficiency particularly when associated with chronic inflammation.	16435056
Crohn Disease, Inflammation	Altered Intercellular Communication	Crohn Disease: mural attenuation and thickness at contrast-enhanced CT Enterography--correlation with endoscopic and histologic findings of inflammation.	16436815
Inflammatory disorder	Altered Intercellular Communication	To determine retrospectively if quantitative measures of small-bowel mural attenuation and thickness at computed tomographic (CT) enterography correlate with endoscopic and histologic findings of small-bowel inflammation and to estimate the performance of these measures in predicting inflammatory Crohn disease.	16436815
Inflammation	Altered Intercellular Communication	In patients who underwent ileal biopsy, threshold attenuation had a sensitivity identical to that of ileoscopy (81% [26 of 32]; 95% confidence interval: 64%, 93%) in predicting histologic inflammation.	16436815
Enteritis	Altered Intercellular Communication	Quantitative measures of mural attenuation are sensitive markers of small bowel inflammation.	16436815
Inflammation, Takayasu Arteritis, Vasculitis, CTCAE	Altered Intercellular Communication	Takayasu's arteritis (TA) is a vasculitis characterized by inflammation and obliteration of intermediate to large-size arteries.	16437361
Colitis	Altered Intercellular Communication	Furthermore, in animal models of colitis, mere oral exposure of mice to yeast does not lead to the induction of marked ASCA titers irrespective of concomitant colonic inflammation.	16437604
Hepatitis	Altered Intercellular Communication	Computer-aided morphometry of liver inflammation in needle biopsies.	16437605
Inflammation, No metabolic abnormalities	Altered Intercellular Communication	Associations between gamma-glutamyl transferase, metabolic abnormalities and inflammation in healthy subjects from a population-based cohort: a possible implication for oxidative stress.	16437656
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Significantly positive correlations were found between fibrosis stage and inflammation grade in the respective scoring systems.	16437668
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The three semiquantitative scoring systems seem to be comparable in the estimation of the inflammation grade and fibrosis stage in this group of children.	16437668
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Non-cancerous lesions of the liver revealed fibrosis at stage F3 with minimal to mild inflammation of grade A1.	16437676
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Elevated plasma von Willebrand factor levels in patients with active ulcerative colitis reflect endothelial perturbation due to systemic inflammation.	16437691
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	To evaluate the plasma von Willebrand factor (vWF) levels in patients with ulcerative colitis (UC) and to investigate their relationship with disease activity, systemic inflammation and coagulation activation.	16437691
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Elevated plasma vWF levels in ulcerative colitis possibly reflect an acute-phase response of the perturbed endothelium due to inflammation.	16437691
Gastrointestinal inflammation	Altered Intercellular Communication	While PrPc enters the organism via the oral route, less data is available to know about its uptake and the role of gastrointestinal inflammation on the expression of prion precursor PrPc, which is constitutively expressed in the gastric mucosa.	16437693
Sepsis	Altered Intercellular Communication	TREM-1 expression is increased during systemic inflammatory conditions such as sepsis and the postoperative phase.	16437719
Inflammation, Cirrhotic, Non-cirrhotic, FAM126A gene	Altered Intercellular Communication	Older HCC patients showed less inflammation and better preservation of hepatic function, indicating that not only cirrhotic patients but also non-cirrhotic patients should be considered as a high-risk group among the elderly.	16437725
Coughing, Inflammation	Altered Intercellular Communication	Angiotensin-converting enzyme (ACE) inhibitors may induce cough and rhinopharyngeal inflammation.	16438479
Airway structure, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	Obstructive sleep apnea (OSA) is characterized by upper airway inflammation.	16438479
Airway structure, Osage language	Altered Intercellular Communication	These findings suggest that ACE inhibitor treatment may contribute to OSA by inducing upper airway inflammation.	16438479
Inflammation	Altered Intercellular Communication	In patients undergoing off-pump CABG, it is plausible that inflammation is associated with the development of postoperative AF.	16439145
Inflammation, Neoplasms	Altered Intercellular Communication	The cause was unknown but not from inflammation or tumor.	16440717
Communicable Diseases, Inflammation, Tissue injury, Hepatitis B	Altered Intercellular Communication	Polymorphisms in cytokine genes can influence immune responses, inflammation and tissue injury, and may affect the outcome of hepatitis B virus (HBV) infection.	16441483
Granulomatous inflammation, Virus Diseases	Altered Intercellular Communication	The prognostic significance of the association of granulomatous inflammation and virus infection is reviewed.	16441629
Granulomatous inflammation	Altered Intercellular Communication	Histologically, granulomatous inflammations were found in the upper to mid dermis.	16441629
Inflammation, Anemia	Altered Intercellular Communication	The purpose of the study is to compare the evolution of the following aspects before and after starting online HDF: dose of dialysis, purification of medium-sized/large molecules, inflammation, nutrition, Ca-P metabolism, anemia, and intradialytic complications.	16441865
Inflammation, Neoplasms, Periorbital Infection, Abnormality of the vasculature, Traumatic injury, Exophthalmos	Altered Intercellular Communication	Neoplasms (33%) were the most common causes of proptosis in all the patients followed by orbital inflammations (23%), orbital infections (20%), structural abnormalities (12%), vascular abnormalities (7%) and trauma (5%).	16441987
Ischemia, Inflammation, Demographics Domain, Diabetes Mellitus, Acute Coronary Syndrome, Myocardial, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	The present study evaluated whether biomarkers of ischemia, inflammation, myocardial damage, and dysfunction are equally useful in patients who have diabetes mellitus (DM) for prediction of cardiac events in non-ST-elevation acute coronary syndrome (ACS).	16442356
Inflammation, Dental Plaque, Restenosis	Altered Intercellular Communication	In conclusion, enhanced inflammation of plaque (increased sCD40L) before percutaneous coronary intervention may increase the rate of stent restenosis.	16442363
Atrial Fibrillation, Inflammation	Altered Intercellular Communication	This study explored whether the CRP-related incidence of AF is modified by serum markers of inflammation in a population-based cohort with follow-up data.	16442371
Pain Distress Question, Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	An increase in pain with bladder filling was associated with inflammation (P = 0.011), ulceration, and smaller bladder capacity.	16442603
Granulomatous inflammation, Necrobiotic Disorders, Granuloma Annulare	Altered Intercellular Communication	Histologic examination of the biopsy specimens showed granulomatous inflammation with focal necrobiosis, which was consistent with subcutaneous granuloma annulare.	16443113
Necrosis with inflammation	Altered Intercellular Communication	These results suggest that age-related decline in the ATP level reduces the capacity to induce apoptosis and promotes necrotic inflammation.	16443681
Inflammation, Dental Plaque, Diabetes Mellitus	Altered Intercellular Communication	Children with diabetes had significantly higher plaque and gingival inflammation levels compared with control subjects.	16443876
Airway structure, Asthma	Altered Intercellular Communication	With regard to understanding of the nature, prognosis and treatment of asthma, 96.6% of the parents did not know the role of airway inflammation on synthesis of symptoms and 51.7% believed in a cure for the disease.	16444341
Inflammation, Edema	Altered Intercellular Communication	Computed tomography of the abdomen demonstrated enlarged liver and pancreas with edema and inflammation.	16444390
vascular inflammations, Dental Plaque	Altered Intercellular Communication	Statins such as atorvastatin, as lipid-lowering agents, can not only normalise serum lipid levels, but also may improve endothelial function, reduce vascular inflammation and enhance plaque stability.	16444629
Inflammation	Altered Intercellular Communication	The peritoneal cavity sanation, depending on the inflammation character and extension, was performed using from 1 to 91 of antiseptic solution and assistance of irrigation-aspiration system.	16445034
Degenerative polyarthritis, Short-Wave Therapy, Inflammation, Pain Distress Question	Altered Intercellular Communication	Shortwave (SW) diathermy can be used to improve vascular circulation and reduce inflammation and pain for patients with osteoarthritis.	16445337
Inflammation	Altered Intercellular Communication	However, reduction in synovial inflammation has never been explored.	16445337
Necrotizing granulomatous inflammation, Crohn Disease	Altered Intercellular Communication	Endoscopic examination and a colon biopsy specimen showed chronic granulomatous inflammation consistent with Crohn disease.	16445412
Inflammation, Necrotizing fasciitis	Altered Intercellular Communication	Cervical necrotizing fasciitis is a fast spreading acute soft tissue inflammation.	16446008
malignant disease, Endometritis	Altered Intercellular Communication	We suspected a malignant disease, but, the histopathologic examination of biopsies, found an endometrial inflammation without malignant cells.	16446614
Calcified (qualifier), Inflammation, Vegetation, Bacterial Endocarditis	Altered Intercellular Communication	To better define the histological criteria for infective endocarditis, we used quantitative image analysis to compare these 2 groups of patients with respect to vegetations, calcifications, and patterns of inflammation.	16447102
Vegetation, Endocarditis, Bacterial Endocarditis	Altered Intercellular Communication	When no microorganisms are detected and vegetations are not found in bioprosthetic valve tissues during the histological examination, a neutrophil-rich inflammation might better define the term "active endocarditis" in the Duke criteria and would allow differentiation between infective endocarditis and inflammatory, noninfective valve processes in patients with bioprosthetic valves.	16447102
Inflammation, Hemorrhage	Altered Intercellular Communication	We investigated the relationship between inflammation, hemostasis and bleeding after off-pump coronary artery bypass surgery (OPCAB).	16448997
Inflammation, Endometriosis of uterus, Chorioamnionitis, Endometriosis	Altered Intercellular Communication	The resected specimens demonstrated extensive uterine adenomyosis and endometriosis of the cecum, with a fistulous tract lined by endometriosis and suppurative inflammation extending from the cecum to the uterine endometrial cavity associated with severe chorioamnionitis and endomyometritis.	16449145
Airway structure, Asthma	Altered Intercellular Communication	Evaluation of airway inflammation by quantitative Th1/Th2 cytokine mRNA measurement in sputum of asthma patients.	16449261
Polychondritis, Relapsing, Inflammation, Systemic disease	Altered Intercellular Communication	Chronic atrophic polychondritis is a rare systemic disease characterized by recurring inflammation of cartilage of the ear, nose, larynx and of the tracheobronchial tree.	16449929
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Is inflammation a causal chain between low socioeconomic status and type 2 diabetes?	16450207
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	It is unclear, whether inflammation may be a mechanism linking low SES to type 2 diabetes.	16450207
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	In conclusion, inflammation appears not to play a major role linking low SES and type 2 diabetes in the elderly population.	16450207
Chronic Obstructive Airway Disease, Bronchitis	Altered Intercellular Communication	Variability of bronchial inflammation in chronic obstructive pulmonary disease: implications for study design.	16452583
Inflammation	Altered Intercellular Communication	The following four features, when found in combination, were found to be highly predictive of HCN: nonmacrofollicular architecture, absence of colloid, absence of inflammation, and presence of TBV.	16453320
Inflammation, Calculi, Tooth structure, Dental Plaque, Osteopenia	Altered Intercellular Communication	Plaque and calculus accumulation, severe inflammation, tooth mobility, severe horizontal radiographic bone loss, and deep pocketing were observed in teeth affected by the jewelry.	16454012
Bronchial brand of guaifenesin-theophylline, Bronchiolitis	Altered Intercellular Communication	Histological examination of specimens obtained by open lung biopsy revealed bronchiolar inflammation, submucosal bronchial fibrosis with obliteration of bronchiolar lumen.	16454222
Keratitis, Iritis, Episcleritis	Altered Intercellular Communication	GPs also reported several other inflammatory conditions of the eye, amongst them two events each of iritis and episcleritis as well as one of keratitis.	16454542
Intraocular inflammation, Inflammation	Altered Intercellular Communication	Signs of mild, transient intraocular inflammation occurred in 25% of patients, but there was no severe inflammation.	16454650
Inflammation, Platelet aggregation test result	Altered Intercellular Communication	Aspirin can inhibit inflammatory reactions and platelet aggregation, but little is known about the effects of the combination of aspirin plus clopidogrel, a new antiplatelet agent, on inflammation.	16454979
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	The purpose of this study was to determine whether aspirin plus clopidogrel can further suppress inflammation in patients with non-ST-segment elevation acute coronary syndrome (NSTEACS).	16454979
Sinusitis, Particle Size Distribution	Altered Intercellular Communication	The ethmoid sinus inflammation in IPSD is accompanied by a commensurate ipsilateral middle turbinate inflammation.	16455373
Nasal Polyps	Altered Intercellular Communication	Diffuse mucosal inflammation in nasal polyps and adjacent middle turbinate.	16455376
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	To investigate the association of allergy and type of cellular inflammation in Asian patients with NPs.	16455376
Inflammation, Intracranial Aneurysm	Altered Intercellular Communication	Inflammation is thought to play an important role in intracranial aneurysm formation.	16455537
Inflammation, SERPINB3 wt Allele, Neoplasms, Squamous cell carcinoma, Glioma	Altered Intercellular Communication	Recent studies suggest a somewhat selective uptake of O-(2-[18F]fluoroethyl)-L-tyrosine (FET) in cerebral gliomas and in squamous cell carcinoma (SCC) and a good distinction between tumor and inflammation.	16455631
Myositis	Altered Intercellular Communication	Nevertheless, there was no correlation between the level of blood perturbation and muscle inflammation.	16455793
Airway structure, Asthma	Altered Intercellular Communication	Comparison of asthma treatment given in addition to inhaled corticosteroids on airway inflammation and responsiveness.	16455831
Airway structure, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	There is increasing evidence that the assessment of eosinophilic airway inflammation using induced sputum and measurement of airway hyperresponsiveness provides additional, clinically important information concerning asthma control.	16455831
Immune-mediated	Altered Intercellular Communication	Expression of CXCR3-targeting chemokines have been demonstrated in several diseases, suggesting a critical role for CXCR3 in recruiting activated T cells to sites of immune-mediated inflammation.	16456020
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Respiratory syncytial virus, airway inflammation, and FEV1 decline in patients with chronic obstructive pulmonary disease.	16456141
ARCN1 gene, Airway structure	Altered Intercellular Communication	We therefore studied the consequences of RSV persistence in adults with COPD and its effect on airway inflammation and lung function decline.	16456141
ARCN1 gene, Airway structure	Altered Intercellular Communication	Persistent RSV detection in patients with COPD is associated with airway inflammation and accelerated decline in FEV(1).	16456141
Communicable Diseases, Inflammation	Altered Intercellular Communication	Up-regulation of IL-6 may be explained by increased fibroblast activity dependant on an ongoing local inflammation possibly initiated by an infection.	16456693
Inflammation	Altered Intercellular Communication	Mean PEG excretion in patients with impaired mucosa such as inflammation or ulceration of the intestine (0.24 % +/- 0.19, n = 11) was not significantly higher (p = 0.173) compared to that in subjects with macroscopically normal intestinal mucosa (0.13 % +/- 0.13, n = 13).	16456758
allergic inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	The sample patients were diagnosed based on additional tests with allergic inflammation of the nasal mucosa caused by allergy to pollen of such plants as birch, grass, rye, mugwort and plantain.	16457469
Sepsis, Inflammation, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis and sepsis share several pathophysiological similarities, including immune dysregulation, increased thrombogenesis, and systemic inflammation.	16458766
Inflammation, Demyelination	Altered Intercellular Communication	The development of MRI active lesions is strongly reduced by EOD-IFNbeta-1b compared with OW-IFNbeta-1a, indicating that EOD-IFNbeta-1b is more effective than OW-IFNbeta-1a in reducing ongoing inflammation and demyelination in MS. Logistic regression showed that NAb status did not affect the risk of MRI activity.	16459722
Communicable Diseases, Inflammation	Altered Intercellular Communication	The symptoms of infection or inflammation dropped from 22.6 to 7.6%.	16459880
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Can inhaled fluticasone alone or in combination with salmeterol reduce systemic inflammation in chronic obstructive pulmonary disease?	16460562
Inflammation, Primary malignant neoplasm, Osteoporosis, Cardiovascular Diseases, Chronic Obstructive Airway Disease, Weight decreased, Cachexia	Altered Intercellular Communication	Systemic inflammation is associated with various complications in chronic obstructive pulmonary disease including weight loss, cachexia, osteoporosis, cancer and cardiovascular diseases.	16460562
Airway structure, Chronic Obstructive Airway Disease, Exacerbation	Altered Intercellular Communication	Inhaled corticosteroids attenuate airway inflammation, reduce exacerbations, and improve mortality in chronic obstructive pulmonary disease.	16460562
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Whether inhaled corticosteroids by themselves or in combination with a long-acting beta2-adrenoceptor agonist repress systemic inflammation in chronic obstructive pulmonary disease is unknown.	16460562
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	If inhaled corticosteroids by themselves or in combination with a long-acting beta2-adrenoceptor agonist could repress systemic inflammation, they might greatly improve clinical prognosis by reducing various complications in chronic obstructive pulmonary disease.	16460562
Inflammation, Appendicitis, CTCAE, Acute appendicitis NOS (disorder)	Altered Intercellular Communication	The aims of this prospective audit were to define the role of the serum markers of inflammation total white cell count, neutrophil count and C-reactive protein in the diagnosis of acute appendicitis with particular reference to the discrimination between uncomplicated and complicated appendicitis, and the prediction of abscess.	16460636
Opportunistic Infections, Carcinogenesis, Chronic inflammation	Altered Intercellular Communication	These data indicate that arsenic exposure could alter the activation processes of T cells, such that an immunosuppression status that favors opportunistic infections and carcinogenesis is produced together with increased GM-CSF secretion that may be associated with chronic inflammation.	16461332
Inflammation, MS gene	Altered Intercellular Communication	Antibodies to native myelin oligodendrocyte glycoprotein are serologic markers of early inflammation in multiple sclerosis.	16461459
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	No correlation was found with stage of fibrosis, grade of inflammation, alcohol use or other parameters.	16462535
Inflammation, Helicobacter, Gastritis	Altered Intercellular Communication	SLPI expression is generally induced during inflammation; however, Helicobacter pylori-mediated gastritis is associated with significantly decreased antral SLPI levels.	16462541
Gastritis	Altered Intercellular Communication	The aim of the study was to investigate whether SLPI downregulation of gastric mucosa represents a specific phenomenon of H. pylori infection or is generally linked to gastric inflammation.	16462541
Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The local downregulation of SLPI in antral mucosa is specifically linked to H. pylori infection and is not a general phenomenon of gastric inflammation.	16462541
Multiple Organ Failure, Inflammation, Acidosis, Lactic, Liver Dysfunction, Septic Shock, Anemia, Bacterial Infections, Blood Coagulation Disorders, Kidney Failure, Acute	Altered Intercellular Communication	Laboratory tests revealed an inflammation probably due to bacterial infection, anemia, acute renal failure, acute hepatic dysfunction, coagulopathy and lactic acidosis, indicating multi-organ failure and septic shock.	16463229
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	High-sensitivity C-reactive protein (CRP), a marker of inflammation, has been reported to be an independent predictor of future myocardial infarction among clinically healthy individuals.	16464786
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	These data suggest that enhanced inflammation may be associated with homocysteine-related cardiovascular disease, possibly involving IL-6-related mechanisms.	16464786
Inflammation, Fibrosis Assessment, Weight decreased	Altered Intercellular Communication	Cystic fibrosis (CF) is a disease characterized by weight loss and chronic low-grade inflammation.	16464949
Airway structure, Asthma	Altered Intercellular Communication	We previously reported that sputum levels of procollagen type I C-terminal peptide (PICP), a marker of ongoing collagen type I deposition, are increased in proportion to airway inflammation in asthma patients.	16465044
Inflammation, Asthma	Altered Intercellular Communication	The present results suggest that inhaled corticosteroid treatment might reduce sputum indexes of collagen metabolism and eosinophilic inflammation in asthma patients.	16465044
Inflammation, Pathogenic organism, Neoplasm Metastasis, Malignant Neoplasms	Altered Intercellular Communication	Lymphangiogenesis plays an important role in several normal and pathological conditions, such as wound healing, pathogen infection, inflammation or the metastasis formation of endothelial malignancies.	16465426
Inflammation, Arthritis, Gouty, PLAU protein, human	Altered Intercellular Communication	Urokinase-type plasminogen activator, receptor, and inhibitor correlating with gelatinase-B (MMP-9) contribute to inflammation in gouty arthritis of the knee.	16465663
Arthritis, Gouty, Inflammation	Altered Intercellular Communication	These results show a correlation of the PA/plasmin system and MMP-9 in SF from patients with gouty arthritis, resulting in increased PA catalytic activity and contributing to inflammation in gouty arthritis.	16465663
Rotator cuff syndrome, Calcific periarthritis, Inflammation	Altered Intercellular Communication	Two typical clinical courses of calcific periarthritis in the shoulder are known: acute, with severe inflammation, and chronic, in the form of impingement syndrome with secondary subacromial bursitis.	16465665
Acute inflammation	Altered Intercellular Communication	Ten samples were aspirated from 10 women (ages 42-65 yrs) with acute inflammation.	16465665
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	No sign of significant vasculitis or perivascular inflammation was found on radiological or histopathological examination.	16466238
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is predominantly the consequence of chronic smoking exposure, but its development may be influenced by genetic variants that affect lung remodelling, inflammation, and defence from oxidant stress.	16467073
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	IL-6 haplotypes, inflammation, and risk for cardiovascular disease in a multiethnic dialysis cohort.	16467451
Inflammation, Atherosclerosis	Altered Intercellular Communication	It is unknown whether IL-6, a central regulator of inflammation, is a cause of or just a marker of atherosclerosis.	16467451
Inflammation	Altered Intercellular Communication	The IL6 gene has functional variants that affect inflammation and risk for CVD among dialysis patients, supporting a causal role for IL6 in CVD.	16467451
Diplopia, Pain Distress Question, Swelling, Inflammation	Altered Intercellular Communication	The most common presenting symptoms were mass/proptosis, pain, swelling, inflammation, and diplopia.	16468548
Necrotizing granulomatous inflammation	Altered Intercellular Communication	A biopsy of the nodules disclosed epithelioid granulomatous inflammation and resulted in a diagnosis of drug-induced granulomatous reaction to leuprorelin acetate.	16469084
Xanthogranulomatous inflammation	Altered Intercellular Communication	To the best of our knowledge, this is the first report of PLS associated with xanthogranulomatous inflammation.	16469088
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Obesity	Altered Intercellular Communication	We hypothesized that NAFLD would be less severe as a result of younger age and shorter duration of obesity, but portal inflammation and fibrosis would be more prevalent.	16469684
Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Fatty Liver Disease	Altered Intercellular Communication	Eighty-three percent had NAFLD: 24% steatosis alone, 7% isolated fibrosis with steatosis, 32% nonspecific inflammation and steatosis, and 20% nonalcoholic steatohepatitis (NASH).	16469684
Inflammation, Fibrosis Assessment, Fatty Liver Disease	Altered Intercellular Communication	In contrast to morbidly obese adults, lobular inflammation, significant ballooning, and perisinusoidal fibrosis were rare, whereas portal inflammation and portal fibrosis were more prevalent, even in those who did not meet criteria for NASH.	16469684
Inflammation, S100A4 protein, human	Altered Intercellular Communication	Its gene and surface expressions are increased in cases of malignant transformation, inflammation, or T cell activation, whereas normal B and resting T cells lack detectable APN protein expression.	16469741
Inflammation	Altered Intercellular Communication	The lower risk associated with high whole-grain intakes may be mediated through improvements in glycemic control, lipid profiles, or reduced inflammation.	16469984
Inflammation, Anemia, Dyserythropoiesis	Altered Intercellular Communication	Alternatively, anemia may result from cytokine-mediated dyserythropoiesis, as seen in anemia of inflammation.	16469997
Schistosomiasis japonica, Inflammation, Anemia	Altered Intercellular Communication	By evaluating the cross-sectional relation between the intensity of Schistosoma japonicum infection, hemoglobin concentration, and iron status in 7-30-y-old persons from S. japonicum-endemic rice-farming villages in the province of Leyte, Philippines, we assessed the relative contribution of iron deficiency and anemia of inflammation to schistosomiasis-associated anemia.	16469997
Inflammation	Altered Intercellular Communication	We obtained stool samples to quantify S. japonicum infection and venous blood samples for hemograms and measures of iron status and inflammation.	16469997
Communicable Diseases, Inflammation, Anemia	Altered Intercellular Communication	A high prevalence of anemia without iron deficiency, exclusion of other mechanisms of anemia, and the evidence of low bioavailable iron suggest that anemia of inflammation contributes to S. japonicum-associated anemia at all infection intensities.	16469997
Inflammation, Meningitis	Altered Intercellular Communication	In experimental meningitis, adjunctive treatment with steroids reduces cerebrospinal fluid inflammation and thereby improves neurological outcome.	16470361
Inflammation, S100A4 protein, human	Altered Intercellular Communication	This model also explains why non-mutagens can be carcinogens, and why non-mutagenic processes, such as wound healing and chronic inflammation, can promote malignant transformation.	16471036
Inflammation	Altered Intercellular Communication	After obliteration sessions only 2-3 day temperature increase and local inflammation occurred.	16471191
Stomach Carcinoma, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Efficacy of Helicobacter pylori eradication on the chronic mucosal inflammation of the remnant stomach after distal gastrectomy for early gastric cancer.	16471313
Inflammation, Stomach Carcinoma, Atrophic	Altered Intercellular Communication	Eradication therapy could be performed safely and resulted in a significant improvement in inflammation and atrophy of the mucosal layer in the remnant stomach after early gastric cancer surgery.	16471313
Cheilitis, Unknown (origin) (qualifier value)	Altered Intercellular Communication	Plasma cell cheilitis is an idiopathic, benign, inflammatory condition characterized by a dense band-like infiltrate of plasma cells in the oral mucosa.	16471463
Fibrosis Assessment, Necrosis with inflammation	Altered Intercellular Communication	After a mean follow-up 45.5+/-5.8 months weaned patients showed stabilisation/improvement of histological fibrosis (P<0.01), lower necro-inflammation (P<0.02) and improved liver function (P<0.05) compared to weaning-intolerants.	16473433
home health encounter, Traumatic injury, Hypothalamo-Hypophyseal System	Altered Intercellular Communication	In conclusion, in men with HH due to hypothalamic-pituitary disease or injury, the pituitary-testicular hormonal axis maintains its physiological negative feedback between testosterone and gonadotropins.	16474013
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Airway inflammation and bronchial bacterial colonization in chronic obstructive pulmonary disease.	16474030
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Inflammation is now recognized as an integral part of the pathogenesis of chronic obstructive pulmonary disease (COPD).	16474030
Airway structure, ARCN1 gene, Colonization	Altered Intercellular Communication	To test the hypothesis that bacterial colonization is associated with airway inflammation in stable COPD.	16474030
ARCN1 gene, airway disease	Altered Intercellular Communication	Bacterial colonization is associated with neutrophilic airway lumen inflammation in ex-smokers with COPD and could contribute to progression of airway disease in COPD.	16474030
Inflammation	Altered Intercellular Communication	In all patients with normal initial levels of markers of inflammation EF and SV rose.	16474305
Crohn Disease, Spanish Language, Gastrointestinal inflammation, Spondylarthritis	Altered Intercellular Communication	Intestinal inflammation is a common feature of spondyloarthropathy (SpA) and Crohn's disease.	16476712
Inflammation, Crohn Disease	Altered Intercellular Communication	Inflammation is manifested clinically in Crohn's disease and subclinically in SpA.	16476712
Inflammation, Crohn Disease	Altered Intercellular Communication	95 genes were identified as differentially expressed in patients with SpA having a history of subclinical chronic gut inflammation and also in patients with Crohn's disease.	16476712
Inflammation, Crohn Disease	Altered Intercellular Communication	Patients with SpA having subclinical chronic gut inflammation cluster together and are more related to those with Crohn's disease.	16476712
Degenerative polyarthritis, Inflammation, Osteoarthritis, Knee	Altered Intercellular Communication	To compare the effect of celecoxib with that of a classic non-steroidal anti-inflammatory drug (NSAID) on synovial inflammation and on the synovial expression of proinflammatory genes in patients with knee osteoarthritis (OA).	16476713
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Patients with chronic renal disease suffer from accelerated atherogenesis, which is promoted by inflammation and oxidative stress.	16476718
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is thought to contribute to initiation and aggravation of atherosclerosis through a process predominantly mediated by adhesion molecules.	16476720
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	There is increasing evidence that C-reactive protein (CRP) concentration, a measure of inflammation, is an independent risk factor for the development of hypertension in older adults.	16476876
Gastrointestinal inflammation	Altered Intercellular Communication	Gastrointestinal inflammation and the circulating IGF system in humans.	16477536
Gastritis, Colitis, Gastrointestinal inflammation, Duodenitis, Gastrointestinal candidiasis, Crohn Disease, Enteritis	Altered Intercellular Communication	In the present study, circulating IGF-I, IGF-II and their binding proteins (IGFBP-3, IGFBP-2 and IGFBP-1) were determined in 92 adult patients with gastrointestinal inflammation (Crohn's disease, colitis ulcerosa, gastritis, duodenitis errosiva, gastrointestinal candidiasis, and rotaviral and adenoviral enteritis).	16477536
Gastrointestinal inflammation	Altered Intercellular Communication	It may be concluded that the IGF system is seriously imbalanced in patients with gastrointestinal inflammation, regardless of primary cause.	16477536
palladium, Depressed mood, Bipolar Disorder	Altered Intercellular Communication	It is still unclear whether the disturbances of neurotransmitter activities lead to a specific profile of depressive symptoms, that is characteristic for PD and differs from that in depressed patients without PD.	16477585
NCI CTEP SDC Gastroesophageal Cancer Sub-Category Terminology	Altered Intercellular Communication	Evaluation of an inflammation-based prognostic score in patients with inoperable gastro-oesophageal cancer.	16479253
NCI CTEP SDC Gastroesophageal Cancer Sub-Category Terminology	Altered Intercellular Communication	The aim of the present study was to examine whether an inflammation-based prognostic score (Glasgow Prognostic score, GPS) was associated with survival, in patients with inoperable gastro-oesophageal cancer.	16479253
Inflammation, Tumor necrosis	Altered Intercellular Communication	The marker for surfactant degradation was associated with ongoing alveolar inflammation (cellularity of bronchoalveolar lavage fluid and tumor necrosis factor-alpha concentration).	16479381
Morning stiffness - joint, Structure of pelvic girdle, Musculoskeletal Pain	Altered Intercellular Communication	Polymyalgia rheumatica (PMR) is a chronic inflammatory condition of the elderly, characterized by aching and morning stiffness in the cervical region, shoulders and pelvic girdles.	16479743
Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	There is a close relationship between inflammation, malnutrition and atherosclerosis in chronic hemodialysis (HD) patients (pts).	16479823
Inflammation, Gland	Altered Intercellular Communication	In these patients, omeprazole induced a deterioration of the mucosal inflammation scores (P = 0.01) with a numerical increase of glandular atrophy.	16480403
Inflammation, Fibrosis Assessment, Malignant Neoplasms	Altered Intercellular Communication	On microscopic examination, severe fibrosis with hypertrophied nerves was found without any additional findings of malignancy or inflammation.	16482419
Inflammation, Pancreatic carcinoma	Altered Intercellular Communication	To evaluate the contrast-enhanced endosonography as a method of differentiating inflammation from pancreatic carcinoma based on perfusion characteristics of microvessels.	16482625
Cushingoid facies, Adrenal cortical hypofunction	Altered Intercellular Communication	She was a 45-yr-old woman who referred to us because of cushingoid appearance, whose hormonal determinations were suggestive of secondary adrenal insufficiency.	16483182
Inflammation, Hemorrhage	Altered Intercellular Communication	The most common AEs with ranibizumab were reversible inflammation and minor injection-site hemorrhages.	16483659
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Subclinical inflammation is a risk factor for cardiovascular disease.	16483880
Inflammation, Obesity, Abdominal, Metabolic Syndrome X, Atherosclerosis	Altered Intercellular Communication	These results indicate that CRP, a marker of inflammation that underlies atherosclerosis, is associated with the clustering of each metabolic syndrome risk factor and, furthermore, that abdominal obesity is the strongest predictor of CRP level in the Korean adult population.	16483888
Inflammation, Foreign-Body Reaction, Vascular calcification	Altered Intercellular Communication	All AVMs were investigated regarding angionecrosis, angiofibrosis, acute inflammation, chronic inflammation, foreign-body reactions, vascular calcification, blood admixture to embolising cast, and capillary recanalisation within the AVMs.	16484004
methionine, Inflammation, Granulomatous Angiitis	Altered Intercellular Communication	A typical sequence of events depending on MET is observed in all embolised AVMs: acute inflammation with mural angionecrosis is soon replaced by prominent chronic granulomatous vasculitis, which remains stable and is detectable for a very long time, even in AVMs with a MET of more than 6 years.	16484004
Airway structure, Chronic Obstructive Airway Disease, Infection, Exacerbation	Altered Intercellular Communication	Infections and airway inflammation in chronic obstructive pulmonary disease severe exacerbations.	16484677
Inflammation, Atheroma	Altered Intercellular Communication	In conclusion, it is attractive to speculate that hs-CRP, sIL-6R and leptin could act synergistically in course of local inflammatory activity and those molecules may not be just markers of inflammation and cardiovascular risk but are also likely to play a pathogenic role in atheromatous plaque.	16487244
Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain and inflammation after periapical surgery in 60 patients.	16487805
Inflammation, Swelling, Pain Distress Question	Altered Intercellular Communication	Inflammation in turn increased with longer surgical times, and pain and swelling increased with the number of teeth treated.	16487805
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The goal of the present study was, in patients with CKD, to clarify the relationship between the angiographic severity of CAD and serum albumin concentration reflecting either inflammation or nutrition or both.	16488920
Inflammation	Altered Intercellular Communication	It may reflect mainly a state of inflammation.	16488920
Inflammation, Acute myocardial infarction, Reperfusion Injury	Altered Intercellular Communication	Systemic inflammation and reperfusion injury in patients with acute myocardial infarction.	16489260
Inflammation	Altered Intercellular Communication	The role of systemic inflammation in triggering this phenomenon is unknown.	16489260
Inflammation, Reperfusion Injury	Altered Intercellular Communication	Systemic inflammation, in particular high levels of TNF-alpha , is strongly associated with the occurrence of reperfusion injury after successful recanalization.	16489260
Inflammation, Colorectal Carcinoma, Obesity, Diabetes Mellitus	Altered Intercellular Communication	We hypothesize that the peroxisome proliferator-activated receptor-gamma (PPARgamma) is associated with colorectal cancer given its association with insulin, diabetes, obesity, and inflammation.	16489531
Colorectal Carcinoma	Altered Intercellular Communication	These data suggest that PPARgamma may be associated with many aspects of colorectal cancer including insulin- and inflammation-related mechanisms.	16489531
Inflammation, Carcinogenesis	Altered Intercellular Communication	The inducible Cyclooxygenase (COX)-2 enzyme plays an important role in inflammation and carcinogenesis.	16489533
Inflammation, Stricture of duodenum	Altered Intercellular Communication	After the 2-wk treatment, her symptoms were very much improved, and endoscopically, the duodenal stricture and inflammation improved.	16489685
Inflammation, Hemorrhage	Altered Intercellular Communication	On endoscopy, ulceration and inflammation were seen in the ileal pouch together with contact bleeding and mucous discharge.	16489687
Inflammation	Altered Intercellular Communication	SP-A and SP-D may play role in the initiation of immune system and joint inflammation, and may be an integral component of synovial fluid and provide insights for in innate and adaptive immunity within the joint.	16489709
palladium, Periampullary Adenocarcinoma, Pancreatitis, Cholangitis	Altered Intercellular Communication	We evaluated the incidence of chronic pancreatitis and chronic bile duct inflammation in patients undergoing pancreaticoduodenectomy (PD) for suspected periampullary cancer.	16490563
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	The S and M groups had a higher prevalence of rheumatoid factor positivity and erosive disease, and higher levels of markers of systemic inflammation compared with the T group.	16490752
Anxiety, CTCAE 3.0, Cardiac complication, septic	Altered Intercellular Communication	Despite greater environmental microbial contamination, liberalizing visiting hours in ICUs does not increase septic complications, whereas it might reduce cardiovascular complications, possibly through reduced anxiety and more favorable hormonal profile.	16490836
Rheumatoid Arthritis, Inflammation, Atherosclerosis	Altered Intercellular Communication	Patients with rheumatoid arthritis have a high prevalence of preclinical atherosclerosis independent of traditional risk factors, suggesting that chronic inflammation and, possibly, disease severity are atherogenic in this population.	16490910
Inflammation	Altered Intercellular Communication	There are scarce data about the role of inflammation in CAE.	16490963
Vasculitis	Altered Intercellular Communication	These data strongly suggest that more severe vascular wall inflammation may play a role in the pathogenesis of CAE.	16490963
Endophthalmitis, CTCAE, Uveitis	Altered Intercellular Communication	Patients developing postoperative intraocular inflammation and undergoing intravitreal antibiotic injection were included as occurrences of endophthalmitis.	16490973
home health encounter	Altered Intercellular Communication	CaSR abnormalities may help to explain the different calcium- and peptones-induced hormonal responses observed in PH and HH compared with normal subjects.	16491288
Granulomatous inflammation	Altered Intercellular Communication	Ophthalmic examination disclosed granulomatous inflammation in the anterior segment, sunset glow fundus and neovascularization at the optic disc.	16491875
Migraine Disorders, vascular inflammations	Altered Intercellular Communication	Because attacks of migraine may involve repeated sterile vascular inflammation, we measured CRP in migraine patients.	16492227
Inflammation	Altered Intercellular Communication	Interestingly, it converted into a coved type ST-segment elevation, subsequently regressed gradually as acute inflammation improved.	16492309
Inflammation, Carcinogenesis, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation is an important component of carcinogenesis but little research has been conducted on whether inflammation markers can be predictive of cancer risk in humans.	16492932
Inflammation, Primary malignant neoplasm, Breast Cancer Cell	Altered Intercellular Communication	Our results confirm the important role of inflammation in human cancer and suggest that plasma CRP level is a potential marker of increased cancer risk.	16492932
Inflammation, Ischemia, Gastroparesis	Altered Intercellular Communication	The pathogenesis of DGE after PpPD has been speculated to be related to factors such as inflammation, ischemia, gastric atony, motilin levels, and type of surgical procedure.	16495694
Inflammatory Bowel Diseases, Inflammation, Neoplasms, Ulcer, Ulcer of rectum, gastrointestinal	Altered Intercellular Communication	The diagnosis of NSAID colorectal ulceration required the following clinical, histologic and colonoscopic findings: patients presenting with gastrointestinal complaints were taking NSAIDs; presence of colorectal ulcerations confirmed by colonoscopy; no evidence of neoplasm or of specific inflammation in biopsy specimens obtained from the margins of ulcers; no evidence of pathogenic microorganism in cultures of biopsy specimens and stools; no prior history of chronic inflammatory bowel diseases; improvement of ulcers, as confirmed by endoscopy, and improvement of presenting symptoms after the discontinuation of NSAID therapy.	16496059
Inflammation, Atrial Fibrillation, Traumatic injury	Altered Intercellular Communication	In addition to age and catecholamine use, inflammation and severity of injury may be involved in the development of AF in trauma patients.	16496203
Intraocular inflammation	Altered Intercellular Communication	Histology of the enucleated eye showed a marked intraocular inflammation with lymphocytes, epithelioid cells, and multinuclear giant cells grouped around remnants of melanin-bearing cells.	16496265
Inflammation, Perforation (observation)	Altered Intercellular Communication	Probably the inflammation was caused by the infiltration of the appendix wall leading to perforation.	16496779
Inflammation, Psoriasis	Altered Intercellular Communication	These findings confirmed that pro-inflammatory chemokine (IL-8) and adhesion molecules (sE-selectin, sP-selectin, sICAM-1) play an important role in the development and regulation of inflammation in psoriasis.	16497101
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Although the ICAM-1 expression was related to both the degree and the nature of inflammation, the data indicate increased susceptibility of cancer cells to express ICAM-1.	16497620
Inflammation, Tissue injury	Altered Intercellular Communication	Ischemic reperfusion cycle in PTCA leads to the systemic inflammation and extensive tissue injury by the production of reactive oxygen species including nitric oxide (NO) radicals.	16498228
Inflammation, Pancreatitis	Altered Intercellular Communication	Previous studies have shown that matrix metalloproteinase 9 (MMP-9) degrades basement membrane components in inflammation, but the change of serum MMP-9 level in the progression of acute pancreatitis remains unclear.	16498235
Inflammation, Asthma	Altered Intercellular Communication	Elevated arachidonic acid levels in children with asthma may be because of a disturbed balance in the metabolism of n-6 PUFA or may be secondary to inflammation in these patients.	16499639
allergic inflammation	Altered Intercellular Communication	Thymus and activation-regulated chemokine (TARC) and cutaneous T cell-attracting chemokine (CTACK) are responsible for the trafficking of T helper type 2 lymphocytes into sites of allergic inflammation.	16499646
Inflammation, Thrombosis	Altered Intercellular Communication	Sialic acid is an inflammation marker associated with a history of deep vein thrombosis.	16500696
Venous Thrombosis, Inflammation, Deep thrombophlebitis, Atherosclerosis	Altered Intercellular Communication	Deep vein thrombosis (DVT) induces a systemic chronic inflammation and it has been associated with atherosclerosis.	16500696
Inflammation, atherosclerotic	Altered Intercellular Communication	Increased levels of total sialic acid (TSA) have been shown to correlate with inflammation and atherosclerotic processes.	16500696
Inflammation, Secondary Neoplasm	Altered Intercellular Communication	Relationship between serum prostate specific antigen and the pattern of inflammation in both benign and malignant prostatic disease in Middle Eastern men.	16502049
Inflammation	Altered Intercellular Communication	Inflammation was categorized into acute, active chronic and chronic inactive and graded semi-quantitatively according to previously published criteria.	16502049
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Findings from the current study suggest that inflammation through COX-2 pathways may play a role in the progression of BBD to breast carcinoma and that aspirin may help to lower the risk of progression to breast carcinoma among women with BBD.	16502408
Communicable Diseases, Inflammation, Pyelitis	Altered Intercellular Communication	Alkaline encrusted pyelitis is an infectious disease characterised by encrustations in the wall of the upper urinary tract, surrounded by severe inflammation.	16502598
Neurodegenerative Disorders, Inflammation, Diabetic Angiopathies	Altered Intercellular Communication	The cell-surface RAGE [receptor for AGE (advanced glycation end-products)] is associated with the development of diabetic vascular complications, neurodegenerative disorders and inflammation.	16503878
Inflammation, Scleroderma	Altered Intercellular Communication	It follows the line of Blaschko, and occurs without preceding inflammation, subsequent induration or scleroderma.	16503901
Inflammation, Dental Plaque	Altered Intercellular Communication	The mean area of the plaque and the incidence of severe plaque inflammation in group A were significantly lower (4.2+/-3.2; 13.2%) than those in the other two groups (6.6+/-4.3; 84.2%, and 6.3+/-4.4; 52.6%) p<0.01.	16504317
Vasculitis, Chronic liver disease, Dental Plaque	Altered Intercellular Communication	In conclusion, compared with the general population, chronic liver disease patients have coronary arteries with smaller intimal plaque and less vessel inflammation.	16504317
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Atrial fibrillation in athletes: implicit literature-based connections suggest that overtraining and subsequent inflammation may be a contributory mechanism.	16504414
Inflammation	Altered Intercellular Communication	Further searching and literature analysis revealed that excessive endurance exercise or overtraining can lead to chronic systemic inflammation and, separately, that there is a solid association between CRP and AF and that anti-inflammatory agents have been reported to lower CRP and ameliorate AF.	16504414
Inflammation	Altered Intercellular Communication	It is of particular interest to extend recent studies of inflammation in AF to athletes; athletic behavior that can induce inflammation may contribute to understanding the origins of AF.	16504414
Glomerulitis (disorder), Interstitial inflammation, Tubulitis Assessment, Intimal Arteritis Assessment	Altered Intercellular Communication	The Banff index was defined as a sum of all components (value of glomerulitis ["g"] + interstitial inflammation ["i"] + tubulitis ["t"] + arteriolar hyaline thickening ["ah"] + intimal arteritis ["v"]).	16504664
Tubulitis Assessment, Interstitial inflammation	Altered Intercellular Communication	Tubulitis ("t") and interstitial inflammation ("i") displayed no association with renal function at any time.	16504664
Inflammation, Damage, Endothelin	Altered Intercellular Communication	Liver biopsy specimens show a combination of characteristic changes, first observed by Snover as a diagnostic triad: portal inflammation, bile duct damage, and central or portal vein endothelial inflammation (endothelitis or endothelialitis).	16504708
Inflammation, Edema	Altered Intercellular Communication	In conclusion, Sphincterotomy facilitates pancreatic juice outflow by reducing intraoperative graft edema, which could lead to subsequent inflammation.	16504722
Corneal stromal opacities, Conjunctivitis	Altered Intercellular Communication	Conjunctival inflammation was common (29%) and was associated with progressive trichiasis and corneal opacification.	16505016
Conjunctivitis	Altered Intercellular Communication	The pathologic correlates and promoters of conjunctival inflammation need to be investigated.	16505016
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Elevated distribution of collagen indicative of fibrosis coupled with increased cell cycling and high levels of ET-1 and ETA expression in the absence of chronic inflammation suggests altered IMA VSMC regulation is fundamental to the remodeling process.	16505174
Inflammation, Pain Distress Question	Altered Intercellular Communication	The prostaglandins produced by COX-2 are involved in inflammation and pain response in different tissues in the body.	16506214
Inflammation, Carcinogenesis, Prostate carcinoma	Altered Intercellular Communication	This study supports the hypothesis that inflammation is involved in prostate carcinogenesis and that sequence variation within the COX-2 gene influence the risk of prostate cancer.	16506214
Tendinitis, Pain Distress Question, Chondromalacia, Inflammation, Osteochondritis Dissecans, Communicable Diseases, Hallucinations, Sesamoiditis, Rheumatoid Arthritis, Fracture, Arthritis, Gouty, Keratosis, Sesamoid Bones, Avascular Necrosis, CTCAE	Altered Intercellular Communication	Pain at the first metatarsophalangeal (MTP) joint can result from inflammation, chondromalacia, flexor hallucis brevis tendinitis, osteochondritis dessecans, fracture of a sesamoid bone, avascular necrosis of sesamoids, inflamed bursae, intractable keratoses, infection, sesamoiditis, gout arthropathy, and rheumatoid arthritis.	16506237
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Circulating proteins, body iron stores, inflammation, oxidative stress and their interrelationships are abnormal in patients with diabetes and differ between type 1 and type 2 diabetes.	16506275
Diabetes Mellitus	Altered Intercellular Communication	Diabetes is an inflammatory condition associated with iron abnormalities and increased oxidative damage.	16506275
Inflammation, Fibrosis Assessment, Viremia, FAM126A gene, Liver Cirrhosis	Altered Intercellular Communication	Our findings suggest that HCC due to HBV can occur in the serologically-cured stage if progression to pre-cirrhosis or cirrhosis already has occurred, where the fibrosis level has improved considerably because of the long-term absence of active HBV viremia and inflammation.	16506387
Inflammation, Hemolysis (biological function)	Altered Intercellular Communication	Plasma haptoglobin depletion is a reliable marker for the instant diagnosis of accelerated red cell destruction irrespective of the site of haemolysis or the presence of inflammation.	16506966
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Variability in synovial inflammation in rheumatoid arthritis investigated by microarray technology.	16507157
Intraocular inflammation	Altered Intercellular Communication	With a mixture of oral sulfamethoxazole (1600 mg daily) and trimethoprim (320 mg daily), the intraocular inflammation subsided.	16507491
Inflammation, Crohn Disease	Altered Intercellular Communication	Interferon gamma is a potent proinflammatory cytokine implicated in the inflammation of Crohn's disease (CD).	16507585
Inflammation	Altered Intercellular Communication	We report three elderly men with high serum IgG4 concentrations and multiple lymphoplasmacytic inflammation of the salivary glands, lymph nodes, pancreas, and renal interstitium.	16508232
Inflammation, Retinal Detachment, thromboembolic, Retinal Perforations, Endophthalmitis, CTCAE	Altered Intercellular Communication	No adverse events were observed, including endophthalmitis, clinically evident inflammation, increased intraocular pressure, retinal tears, retinal detachment, or thromboembolic events in any patient.	16508427
Inflammation, polychondritis	Altered Intercellular Communication	Relapsing polychondritis is characterized by recurrent inflammation and destruction of the cartilage and connective tissue.	16508698
Inflammation, Rheumatoid Arthritis, Lymphoma	Altered Intercellular Communication	Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis.	16508929
Refractory anemias, Rheumatoid Arthritis, Lymphoma	Altered Intercellular Communication	Chronic inflammatory conditions such as rheumatoid arthritis (RA) have been associated with malignant lymphomas.	16508929
Inflammation, Retinitis Pigmentosa, polychondritis, Systemic disease	Altered Intercellular Communication	Relapsing polychondritis (RP) is a rare systemic disease characterized by recurrent inflammation of the cartilaginous structures and connective tissue.	16509158
Inflammation	Altered Intercellular Communication	We report the case of a 67-year-old woman who was hospitalized for degradation of her general state, inflammation and painful shoulders.	16509452
Inflammation, Fibrosis Assessment, liposarcoma	Altered Intercellular Communication	Laparoscopic biopsy permitted the diagnosis of fibrosis with chronic inflammation in one case and liposarcoma in the other.	16509798
Inflammation, Atherosclerosis, Cardiovascular Diseases, HD Term Type, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	We compared the serum levels of metalloproteinases and their inhibitors, markers of SOX, inflammation and atherosclerosis between HD patients (n=40) with and without cardiovascular disease (CVD) and controls (n=20).	16510149
Airway structure, Rhinovirus infection	Altered Intercellular Communication	Carbocisteine may modulate airway inflammation by reducing the production of cytokines in rhinovirus infection.	16510461
Colorectal Carcinoma	Altered Intercellular Communication	We explored whether FHIT might play a role in progression of colorectal cancer through inflammation-associated PGE(2) activity.	16510588
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	Accumulating evidence suggests that inflammation plays a major role in the pathogenesis of motor neuron death in amyotrophic lateral sclerosis (ALS).	16510725
Inflammation, Tumor necrosis	Altered Intercellular Communication	Important mediators of inflammation such as the cytokine tumor necrosis factor-alpha (TNF-alpha) and its superfamily member fibroblast-associated cell-surface ligand (FasL) have been implicated in apoptosis.	16510725
Inflammation, Virus Diseases, Paranasal Sinus Inverted Papilloma	Altered Intercellular Communication	Although it is believed that viral infection, chronic inflammation and cigarette smoking can play an important etiological role, it has recently been suggested that occupational risk factors, such as those involved in malignant epithelial sino-nasal cancer (SNC), can also be involved in causing sino-nasal inverted papilloma.	16512339
Inflammation, Connective Tissue	Altered Intercellular Communication	These disorders were accompanied by changes in biochemical parameters which evidenced the presence of connective tissue destruction and immune inflammation.	16512396
Inflammation, Headache Disorders, Primary	Altered Intercellular Communication	The pathogenesis of primary headaches is differential, with a neurogenic inflammation participation.	16512619
Inflammation, Tension Headache, Migraine Disorders	Altered Intercellular Communication	The aim of this research was to establish whether inflammation participates in the pathogenesis of migraine and tension-type headaches (ETTH).	16512619
Migraine Disorders, Neurogenic Inflammation	Altered Intercellular Communication	Although the significant increase in IL-6 levels observed in several children in the first hour of the migraine attack may suggest that neurogenic inflammation participates in the pathogenesis of migraine.	16512619
Gingivitis	Altered Intercellular Communication	A relationship was found to suggest that patients with MMP exhibit more gingival inflammation than a control population.	16512754
septic, Abrasion	Altered Intercellular Communication	The detection of periprosthetic inflammation using 18F-FDG-PET had a sensitivity of 100% for septic cases and of 45.5% in cases of increased abrasion and aseptic foreign-body reactions.	16512924
vascular inflammations	Altered Intercellular Communication	The data support our previous findings of an association between periodontal organisms and vascular inflammation.	16513386
Communicable Diseases, Atheroma, Inflammation	Altered Intercellular Communication	We conclude that DNA from oral infectious agents is commonly found in atheromas from young but especially from elderly subjects, and that the contribution of C. pneumoniae to the inflammation may be minimal.	16513386
Communicable Diseases, Inflammation	Altered Intercellular Communication	Finally, we have found that the seropositivity of infection and the presence of higher levels of marker of inflammation were correlated with carotid lesion.	16513482
Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Endothelial dysfunction and low-grade inflammation explain much of the excess cardiovascular mortality in individuals with type 2 diabetes: the Hoorn Study.	16514084
Inflammation, Endothelial dysfunction, Cardiovascular Diseases	Altered Intercellular Communication	It is commonly held that endothelial dysfunction and low-grade inflammation can explain, at least in part, why deteriorating glucose tolerance is associated with cardiovascular disease.	16514084
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	In this population-based study (n=631), T2D was cross-sectionally associated with both endothelial dysfunction and low-grade inflammation, whereas impaired glucose metabolism (IGM) was associated only with low-grade inflammation.	16514084
Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Finally, T2D-associated endothelial dysfunction and low-grade inflammation explained approximately 43% of the increase in cardiovascular mortality risk conferred by T2D.	16514084
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Although oxygen therapy is of clear benefit in patients with severe chronic obstructive pulmonary disease (COPD), recent studies have shown that short-term supplementary oxygen may increase oxidative stress and inflammation within the airways.	16514109
ARCN1 gene, Inflammation	Altered Intercellular Communication	We investigated whether systemic inflammation and oxidative stress at rest and during exercise in patients with COPD are influenced by supplemental oxygen.	16514109
Inflammation	Altered Intercellular Communication	Short-term oxygen breathing at rest did not influence systemic low-grade inflammation and oxidative stress.	16514109
ARCN1 gene, Inflammation	Altered Intercellular Communication	Short-term supplementary oxygen does not affect basal systemic inflammation and oxidative stress but prevents exercise-induced oxidative stress in normoxemic, muscle-wasted patients with COPD, and attenuates plasma IL-6 response.	16514109
Inflammation	Altered Intercellular Communication	It has clinical signs of severe local inflammation as a result of an exaggerated inflammatory response, but neurogenic dysregulation also may contribute to it.	16514322
Inflammation	Altered Intercellular Communication	Since the activation precedes synovial inflammation, it is suggested that the leukocytes play an important role as an initiator in the pathogenesis of acute hemarthrosis.	16514634
Arthritis	Altered Intercellular Communication	In 3 of 10 patients with chronic arthritis joint inflammation persisted.	16514819
BAP1 gene	Altered Intercellular Communication	We hypothesize that the AR gene, involved in endocrine signaling, may modify BRCA1-associated ovarian cancer risk.	16515589
Necrotizing granulomatous inflammation	Altered Intercellular Communication	The pathological examination of the liver biopsy revealed eosinophil-rich necrotizing granulomatous inflammation with Toxocara spp larva.	16516616
Acute Coronary Syndrome, Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	The objectives of this study were to examine the time course of the inflammatory response in acute coronary syndromes (ACS) and to assess the markers of inflammation and their relation to disease severity.	16516698
septic	Altered Intercellular Communication	PBMCs from septic patients, but not following surgical injury, have a reduced capacity to respond to a secondary inflammatory signal, but this defect is not associated with reduced TLR-4 or CD14 expression.	16517212
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterised by both airway inflammation and systemic changes.	16517575
Inflammation, Intraductal Hyperplasia	Altered Intercellular Communication	The presence of yellowish superficial lesions suggested intraductal inflammation or superficial hyperplasia of the duct epithelium.	16518070
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	Novel -209A/G MT2A polymorphism in old patients with type 2 diabetes and atherosclerosis: relationship with inflammation (IL-6) and zinc.	16518702
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, NEUROD1 wt Allele, Atherosclerosis	Altered Intercellular Communication	Chronic inflammation due to high IL-6 production occurs in type 2 diabetes (NIDDM) and atherosclerosis.	16518702
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	Zinc deficiency is an usual event in ageing, inflammation, type 2 diabetes and atherosclerosis.	16518702
Inflammation, Zinc deficiency, Hyperglycemia	Altered Intercellular Communication	The -209 A/G MT2A polymorphism is associated with chronic inflammation (higher plasma levels of IL-6), hyperglycaemia, enhanced HbA1c and more marked zinc deficiency in AA than AG genotype carrying patients.	16518702
Inflammation	Altered Intercellular Communication	All in all our data seem to suggest that reduction of -330G allele frequency might be protective for healthy ageing limiting cell mediated inflammation implied in age associated diseases.	16518704
Inflammation, Diverticulitis	Altered Intercellular Communication	Sigmoid colectomy for diverticulitis can be technically challenging because of severe inflammation in the left-lower quadrant and pelvis.	16518715
Inflammation, Chorea, Hypermetabolism	Altered Intercellular Communication	Hypermetabolism in bilateral caudate nuclei, especially on the right, was found on FDG-PET study, which was compatible with his left side-dominant chorea and might reflect inflammation as a nature.	16519113
Inflammation, Hemorrhage	Altered Intercellular Communication	No signs of inflammation and/or bleeding were observed.	16519183
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Signs of inflammation and destruction in the finger joints are the principal features of rheumatoid arthritis (RA).	16519793
Finger joint structure, Inflammation, Destruction (action)	Altered Intercellular Communication	The objective of the present study was to investigate whether ultrasonography can provide information on signs of inflammation and destruction in RA finger joints that are not available with conventional radiography and clinical examination, and comparable to the information provided by magnetic resonance imaging (MRI).	16519793
Finger joint structure, Inflammation, Destruction (action)	Altered Intercellular Communication	With MRI as the reference method, ultrasonography had higher sensitivity and accuracy in detecting signs of inflammation and destruction in RA finger joints than did clinical and radiographic examinations, without loss of specificity.	16519793
Inflammation, Aortic Aneurysm, Abdominal, Cardiovascular Diseases	Altered Intercellular Communication	Reduced lung function in patients with abdominal aortic aneurysm is associated with activation of inflammation and hemostasis, not smoking or cardiovascular disease.	16520158
Inflammation, Aneurysm	Altered Intercellular Communication	We hypothesize that activation of inflammation and hemostasis in response to injury may be an important explanation of the association between aneurysm formation and reduced respiratory function.	16520158
Inflammation	Altered Intercellular Communication	Pathologically, chronic inflammation was observed in the surrounding tissue.	16520222
Congestive heart failure	Altered Intercellular Communication	Statins may be of potential benefit in patients with congestive heart failure (CHF) due to modulation of neurohormones and their antioxidant, antiinflammatory, and antifibrotic properties.	16520262
Inflammation, Atherosclerosis	Altered Intercellular Communication	The low molecular weight forms of AGEs predict mortality in patients receiving chronic haemodialysis, and may be important in the mechanisms leading to atherosclerosis and inflammation in such patients.	16520354
Tumor necrosis	Altered Intercellular Communication	The gene polymorphisms screened were: alcohol sensitivity-associated polymorphisms of alcohol dehydrogenase (ADH2) Arg47His, aldehyde dehydrogenase (ALDH2) Glu487Lys, smoking sensitivity-associated polymorphisms of glutathione S transferase (GST) M1, (GST)T1, NAD(P)H quinone oxidoreductase 1 (NQO1) C609T, inflammation-associated polymorphisms of interleukin-1beta (IL-1B)T-31C, tumor necrosis factor alpha (TNF-alpha) T-1031C, endothelial constitutive nitric oxide synthase (ecNOS) Glu298Asp, longevity-associated polymorphism of mitochondrial DNA (mtDNA) 5178 A/C, allergy-associated polymorphism of interleukin-4 (IL-4), and immunity-associated polymorphism of CD14.	16520888
Inflammation	Altered Intercellular Communication	We propose that acid-base and ionic-protein gradient may lead to instability of subsaturated urate solution, thereby predisposing to MSUM deposits within synovial membrane and inducing inflammation.	16521049
Inflammation, Behcet Syndrome	Altered Intercellular Communication	The resected specimen was histologically compatible with intestinal Behcet's disease showing severe inflammation with deep ulcerations and neutrophil accumulation.	16521233
Inflammation, Abnormality, Glossitis	Altered Intercellular Communication	[Median rhomboid glossitis--change of inflammation origin or developmental anomaly?].	16521451
Inflammation, Cerebral Infarction, CNS disorder, Creutzfeldt-Jakob disease, MS gene	Altered Intercellular Communication	Previous studies have reported that emperipolesis occurs in various CNS diseases showing destruction of myelin or inflammation of the white matter, including multiple sclerosis, cerebral infarct and CJD.	16521481
Inflammation, Intestinal Obstruction	Altered Intercellular Communication	Out of this group 239 cases presented peritoneal diffuse inflammation and 104 were diagnosed with bowel obstruction.	16521491
Inflammation, Intestinal Obstruction	Altered Intercellular Communication	mortality rate patients with peritoneal diffuse inflammation was 51.05%, and was higher than patients with bowel obstruction 48.08%.	16521491
Multiple Organ Failure, Communicable Diseases, Inflammation	Altered Intercellular Communication	The difference in these values was caused by infection by pathogenic bacteria of gastrointestinal tract and most frequently by the appearance of multiorgan dysfunction in the group with peritoneal diffuse inflammation, despite lower punctation in the APACHE II and TISS-28 score system.	16521491
Inflammation, Escherichia coli Infections	Altered Intercellular Communication	Malakoplakia is a specific type of chronic inflammation coexisting with Escherichia coli infection.	16521507
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The objective was to examine the associations between dietary and plasma vitamin C concentrations, fruit and vegetable intakes, and markers of inflammation and hemostasis associated with cardiovascular disease in older men free of cardiovascular disease.	16522902
Intraocular inflammation	Altered Intercellular Communication	During follow-up, mean intraocular pressure was normal, and there was a significant intraocular inflammation in three cases (4.5%).	16523153
Glaucoma, CTCAE, Uveitis	Altered Intercellular Communication	Complications included glaucoma (eight eyes), major emulsification (two eyes), and an intraocular inflammation reaction to topical steroids (five eyes).	16523154
Intraocular inflammation, Neurologic Signs	Altered Intercellular Communication	After 24 months of follow-up, best-corrected visual acuity was 20/200 in the right eye and 20/25 in the left; no signs of intraocular inflammation were observed and neurological signs had resolved.	16523295
Apolipoproteins B, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus	Altered Intercellular Communication	Since adiponectin and chronic subclinical inflammation have been reported to predict the development of type 2 diabetes and since abnormalities in apolipoprotein B metabolism occur in the early course of insulin resistance, these findings may be compatible with the association between liver markers and risk of diabetes.	16523413
Periampullary Adenocarcinoma	Altered Intercellular Communication	Ampullary xanthogranulomatous inflammation mimicking periampullary cancer: report of a case.	16525208
Periampullary Region, Inflammation	Altered Intercellular Communication	Xanthogranulomatous inflammation should be added to the differential diagnosis of patients presenting with a suspected periampullary lesion accompanied by a thick-walled gallbladder.	16525208
Inflammation	Altered Intercellular Communication	These findings provide further support to the important role of inflammation in the pathogenesis of CVD.	16525580
HD Term Type, Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation (CRP> 10 mg/l) was present in 58.1% of HD patients and was associated with higher values of all ultrasonographic markers of atherosclerosis, as well as higher prevalence of atherosclerotic vascular diseases.	16526209
HD Term Type, Inflammation, Atherosclerosis	Altered Intercellular Communication	Results of our investigation support the concept on key role of inflammation in the development of atherosclerosis in HD patients.	16526209
Adipose tissue, Chronic inflammation	Altered Intercellular Communication	Ectopic decidua was infiltrated by blood and surrounded with adipose tissue necrosis and mild chronic inflammation.	16526221
Inflammation, Aortic Stiffness	Altered Intercellular Communication	Among others, aortic stiffness has been correlated with serum markers of inflammation, indicating a role of the immune system in its pathogenesis.	16526321
HD Term Type, Inflammation, Aortic Stiffness	Altered Intercellular Communication	This is in agreement with the observation that aortic stiffness in HD patients is positively related to various serum inflammation markers.	16526321
Acute Cholecystitis	Altered Intercellular Communication	All 3 patients had previously undergone open subtotal cholecystectomy for severe acute cholecystitis when complete cholecystectomy could not be performed because of dense acute inflammation.	16527703
Dacryoadenitis, Neuritis, Myositis, CTCAE 5.0, Orbital Pseudotumor, Eyelid Neoplasms	Altered Intercellular Communication	According to radiological and surgical findings, a local mass within the orbit was the most frequent subtype (50%), followed by dacryoadenitis (29%), myositis (8%), perineuritis (4%), eyelid pseudotumor (4%), and diffuse orbital inflammation (4%).	16527767
Inflammation	Altered Intercellular Communication	All patients notified because of inflammation, all were operated on with microscope without external section.	16529054
Fibrosis Assessment, Hepatic inflammation, Hepatitis B, Liver Cirrhosis	Altered Intercellular Communication	Cirrhosis develops as a result of hepatic inflammation and subsequent fibrosis in chronic hepatitis B infection.	16530509
nervous system disorder, Tremor, CTCAE 3.0	Altered Intercellular Communication	The gamma-aminobutyric acid A (GABA-A) receptor mediates inhibitory neurotransmission in the brain and as such may be involved in certain neurological movement disorders, such as tremor.	16530959
Inflammation, Fatty degeneration, Liver diseases, Fatty Liver Disease	Altered Intercellular Communication	The diagnosis of NASH was based on 1) presence of steatosis, inflammation and ballooning on liver biopsy 2) Intake of alcohol < 20 gm of ethanol per week 3) Exclusion of other liver diseases.	16531962
Inflammation, Hyperplastic Polyp, Vasculitis, CTCAE	Altered Intercellular Communication	In conclusion, neutrophil and platelet MP levels are non-specific markers of neutrophil activation during vasculitis acute phase and dialysis-induced inflammation.	16531979
Inflammation	Altered Intercellular Communication	Circulating aggregates of neutrophil/platelet MPs co-express adhesion molecules of both cell types and may be thus endowed with inflammation and coagulation- thus modulating properties.	16531979
Hepatosplenomegaly, Inflammation, Exanthema, Sensorineural Hearing Loss (disorder), Chronic fever	Altered Intercellular Communication	We describe the case of a 5-year-old boy with neonatal onset of urticaria-like rash, chronic fever, laboratory findings of systemic inflammation, hepatosplenomegaly, and chronic CNS inflammation associated with sensorineural deafness.	16532456
Inflammation	Altered Intercellular Communication	Chronic inflammation from any source is associated with increased cardiovascular risk.	16534043
Inflammation, Periodontitis	Altered Intercellular Communication	Periodontitis is a possible trigger of chronic inflammation.	16534043
Inflammation, Weight decreased	Altered Intercellular Communication	Elevated levels of inflammation factors often precede weight loss and may be causally related to it.	16534520
Weight Gain, Inflammation	Altered Intercellular Communication	Newer studies suggest that elevated levels of inflammation factors also precede weight gain.	16534520
Weight Gain, Weight decreased	Altered Intercellular Communication	Inflammation factors are associated with weight gain and weight loss in older individuals.	16534520
Inflammation	Altered Intercellular Communication	These findings suggest that subclinical inflammation, or unknown factors associated with subclinical inflammation, contribute to weight change.	16534520
Inflammation, Pathologic TNM Finding	Altered Intercellular Communication	In infiltrative TC, the presence of oxidative stress markers was not significantly correlated with histological grade, density of inflammation, the depth of infiltration (pT), lymph nodes dissemination (pN) and pathological stages (pTNM).	16534838
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Chronic inflammation is a common feature of osteoarthritis (OA).	16536221
Inflammation	Altered Intercellular Communication	Cellular attachment to and migration into ST is one of the critical aspects of chronic inflammation.	16536221
adult nasal type extranodal NK/T-cell lymphoma	Altered Intercellular Communication	To compare the detection rate of Epstein-Barr virus latent membrane protein 1 (LMP1) 30 base pair deletion in extranodal nasal type NK/T-cell lymphoma with that in chronic inflammation of nasopharynx and tonsillitis; and to analyze the prognostic significance of LMP1 deletion in extranodal nasal type NK/T-cell lymphoma.	16536316
adult nasal type extranodal NK/T-cell lymphoma	Altered Intercellular Communication	Polymerase chain reaction was used to detect the deletion of LMP1 in 55 cases of extranodal nasal type NK/T-cell lymphoma and 19 cases of chronic inflammation of nasopharynx and tonsillitis.	16536316
Aneurysm, Inflammation	Altered Intercellular Communication	The correlation of iNOS expression with age of the patient, size of aneurysm, and degree of inflammation was also investigated by Cochran-Mantel-Haenszel chi2 test and Kendall' Tau correlation.	16537027
APP gene, Inflammation	Altered Intercellular Communication	SMCs and inflammatory cells were main cellular sources of increased iNOS in AAA, and NO may play a part in pathogenesis in AAA through inflammation.	16537027
Inflammation, Prostate carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Chronic or recurrent inflammation has been suggested as a causal factor in several human malignancies, including prostate cancer.	16537705
Acute and chronic inflammation, Adenoma of large intestine	Altered Intercellular Communication	It is possible that single-nucleotide polymorphisms in inflammatory genes may play a role in chronic colonic inflammation and development of colorectal adenomas.	16537707
Inflammation, Thrombosis	Altered Intercellular Communication	Circulating levels of beta2-glycoprotein I in thrombotic disorders and in inflammation.	16539279
Inflammation, Thromboembolism	Altered Intercellular Communication	However, little is known about its circulating levels in common thrombotic diseases or inflammation.	16539279
Inflammation, Nasal Polyps, Allergy - Charge Type Reason	Altered Intercellular Communication	Nasal polyposis: role of allergy on therapeutic response of eosinophil- and noneosinophil-dominated inflammation.	16539303
Inflammation, Smell Perception	Altered Intercellular Communication	Men showed higher prevalence of olfactory loss secondary to inflammation and toxin exposure.	16539304
Craniocerebral Trauma, Inflammation, Congenital MeSH qualifier	Altered Intercellular Communication	Patients with inflammation scored better than patients with other diagnoses (i.e., congenital, head trauma, postviral, toxin exposure, and miscellaneous causes).	16539304
Inflammation, Cardiovascular Diseases, Refractory anemias, Rheumatoid Arthritis, Endothelial dysfunction	Altered Intercellular Communication	Systemic inflammation, insulin resistance, and endothelial dysfunction have been implicated in the development of cardiovascular disease in rheumatoid arthritis (RA).	16539824
Atrial Fibrillation, Inflammation, Cardiac Arrhythmia	Altered Intercellular Communication	Recently, it has been shown that the C-reactive protein (CRP) level is elevated in patients with AF, indicating that inflammation may play a role in the pathogenesis of this arrhythmia.	16540033
Inflammation	Altered Intercellular Communication	A high CRP level is associated with early recurrence of AF after electrical cardioversion, suggesting that inflammation could play a role in atrial remodeling.	16540033
Angina Pectoris, vascular inflammations, Microvascular Angina, Exercise-induced lactic acidemia	Altered Intercellular Communication	Increased oxidative stress and vascular inflammation have been shown in patients with cardiac syndrome X (CSX; angina, exercise-induced ischemia, and normal coronary angiogram).	16540394
Granulomatous inflammation, Pseudolymphoma	Altered Intercellular Communication	Skin biopsies showed a background of T-cell-rich reactive lymphoid hyperplasia in 7 of 10 patients, with variable granulomatous inflammation in 5 cases.	16540723
Inflammation, Chlamydia, Cardiovascular Diseases	Altered Intercellular Communication	Chlamydia pneumoniae antibodies and markers of inflammation in patients with cardiovascular diseases.	16541617
Meningitis	Altered Intercellular Communication	Neurological examination showed meningeal signs, and cerebrospinal fluid (CSF) examination revealed meningeal inflammation which contained 450 polymorphonuclear cells/microl, 302 mononuclear cells/microl, and 0 red cells/microl, with 79 mg protein/dl.	16541793
Steatohepatitis, Bronchitis, Duodenal inflammation	Altered Intercellular Communication	History was notable for high transaminase levels, hepatic steatosis sinusitis, chronic bronchitis, and duodenal inflammation.	16541975
Inflammation, Hypercholesterolemia, Hypothyroidism	Altered Intercellular Communication	Altered coagulation parameters, elevated lipoprotein (a) levels, and low-grade chronic inflammation are regarded to coalesce with the hypercholesterolemia of untreated patients with subclinical hypothyroidism to enhance the ischemic cardiovascular risk.	16542047
Pain Distress Question, Inflammation	Altered Intercellular Communication	Ibuprofen is a nonsteroidal anti-inflammatory drug available over the counter and on prescription for the management of pain and inflammation.	16542487
Inflammation, Arthritis, Synovitis	Altered Intercellular Communication	Activity of arthritis was determined by routine parameters for systemic inflammation, by histological scoring of synovitis and by semiquantitative RT-PCR of IL-1beta, TNF-alpha, stromelysin and collagenase I in synovial tissue.	16542506
Sleeplessness, Inflammation	Altered Intercellular Communication	Compared with men, women with stable CAD may be especially at risk of experiencing poor sleep quality, even when sleeplessness behavior and pharmacologic treatments with inflammation inhibitors are controlled.	16543036
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Evidence supporting the contribution of oxidative stress to key pathways in cancer, such as inflammation and DNA damage, continues to mount.	16543247
Inflammation	Altered Intercellular Communication	Independent replication of our findings are warranted and further evaluation of oxidative stress in the context of inflammation, DNA repair and the induction of the NF-kappaB pathway may further reveal important clues for lymphomagenesis.	16543247
Kidney Failure, Chronic, Inflammation, Electronic Source Report Form	Altered Intercellular Communication	To investigate this hypothesis as well as the relationship between telomerase and inflammation, we measured the activity of this reverse transcriptase as well as the level of several inflammatory markers in PBMCs and serum of an end-stage renal failure (ESRF) population and a non-renal-failure group of subjects.	16543712
Acquired Immunodeficiency Syndrome, Toxoplasmosis, Orbital Pseudotumor	Altered Intercellular Communication	Optic nerve toxoplasmosis and orbital inflammation as initial presentation of AIDS.	16544111
Communicable Diseases, Inflammation, Vascular Diseases	Altered Intercellular Communication	Associations of serologic markers of infection and inflammation with vascular disease events and mortality in American dialysis patients.	16544178
Chronic infectious disease, Inflammation, Vascular Diseases	Altered Intercellular Communication	The relationship of chronic infections to inflammation and vascular disease events has not been reported among American dialysis patients.	16544178
Inflammation, Bacterial Infections	Altered Intercellular Communication	Oxidative stress is an intrinsic part of the chain of events leading to inflammation of the airways caused by bacterial infection.	16545248
Inflammation	Altered Intercellular Communication	An etiologic role for chronic inflammation in the development of insulin resistance has been hypothesized.	16546475
Inflammation	Altered Intercellular Communication	These results suggest that CSMD1 may be an important regulator of complement activation and inflammation in the developing CNS, and that it may also play a role in the context of growth cone function.	16547280
Vasculitis, Rupture	Altered Intercellular Communication	The diagnosis of rupture and retroperitoneal mass was made by computed tomography, whereas FDG -PET diagnosed vessel wall inflammation.	16547362
Inflammation	Altered Intercellular Communication	A liver biopsy disclosed an altered lobulillar structure with chronic inflammation and the formation of collagen bands.	16547695
Inflammation, Atrophic	Altered Intercellular Communication	Degrees of inflammation and atrophy in the corpus of the stomach were evaluated histologically.	16549394
Inflammation, Atrophic	Altered Intercellular Communication	Anti-parietal cell antibody titre was high when inflammation in the corpus was severe (p=0.06) and significantly low when atrophy in the corpus was severe (p=0.01).	16549394
Inflammation, Cholangiocarcinoma, Acholic stool, Icterus, Pruritus	Altered Intercellular Communication	We report herein an uncommon association of chronic inflammation of the papilla and viral CMV inclusions with distal cholangiocarcinoma in a 72-year-old woman who presented jaundice, choluria, acholia and generalized pruritus.	16549927
Inflammation, Cytomegalovirus	Altered Intercellular Communication	Pathology revealed an enlarged papilla, due to chronic inflammation with CMV inclusions.	16549927
Parkinson Disease, Inflammation, palladium	Altered Intercellular Communication	Inflammation and oxidative stress have been implicated as pathogenic mechanisms in Parkinson's disease (PD).	16550541
Inflammation, Pancreatic Intraductal Papillary Mucinous Neoplasm, Carcinoma	Altered Intercellular Communication	In addition, significant background inflammation (neutrophils and histiocytes) was found to be more characteristic of IPMN with at least carcinoma in situ (P = .002).	16550572
Inflammation, Dysplasia, Carcinoma, Neoplasms	Altered Intercellular Communication	The presence of tight epithelial cell clusters is consistent with a neoplasm of at least moderate dysplasia, and abundant background inflammation and parachromatin clearing correlated with the presence of at least carcinoma in situ.	16550572
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Liver biopsy showed severe portal and moderate lobular inflammation, patchy necrosis, moderate fibrosis and several "ground glass" cells.	16550752
Inflammation, Hypertension, CTCAE, Diabetes Mellitus, Congestive heart failure	Altered Intercellular Communication	Stepwise adjustment for inflammation, hypertension, insulin resistance, and diabetes mellitus did not decrease the relative risk of a greater waist circumference for the development of CHF (all HR=1.27-1.32, 95% CI=1.02-1.61 per SD increase).	16551307
Inflammation, Observation Method - Coagulation, Depression, CTCAE, Disease	Altered Intercellular Communication	Demographic and lifestyle factors, depression, diseases, and medication that could affect inflammation, coagulation, and sleep were controlled for in analyses regressing sleep variables and caregiver status and their interaction on plasma levels of IL-6 and D-dimer.	16551309
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	Obesity, inflammation, insulin resistance and cardiovascular disease (CVD) risk are inter-related.	16552404
Autoinflammatory Syndrome, Sinusitis	Altered Intercellular Communication	Paranasal sinus inflammation and non-specific orbital inflammatory syndrome: an uncommon association.	16552528
Sinusitis	Altered Intercellular Communication	The aim of this study is to present a series of patients with orbital inflammatory symptoms associated with significant paranasal sinus inflammation, and to discuss the diagnostic and management modalities.	16552528
Autoinflammatory Syndrome, Sinusitis	Altered Intercellular Communication	A retrospective, non-comparative, interventional case series of all patients diagnosed with orbital inflammatory syndrome and significant sinus inflammation, seen at two Orbital Units between January 1999 and October 2005.	16552528
Autoinflammatory Syndrome, Sinusitis	Altered Intercellular Communication	Of 91 cases diagnosed with non-specific orbital inflammatory syndrome, six (6.6%, four males, two females mean age 51+/-17 years) had significant sinus inflammation.	16552528
Abnormal peripheral nervous system synaptic transmission, Ulcer	Altered Intercellular Communication	It could depend on the alterations of smooth muscles cable properties, increase of connective tissue mass, changes in the intestinal nervous system and synaptic transmission in the region adjacent to duodenum ulcer.	16553299
Inflammation, Calcification of coronary artery	Altered Intercellular Communication	Inflammation, mineral metabolism and progressive coronary artery calcification in patients on haemodialysis.	16554319
Kidney Failure, Chronic, Inflammation, SLC25A20 gene	Altered Intercellular Communication	These data suggest that chronic inflammation as well as altered mineral metabolism contributes to a rapid progression of CAC in ESRD patients.	16554319
Kidney Failure, Chronic, Carotid Atherosclerosis, Inflammation	Altered Intercellular Communication	In ESRD, the Leu554Phe polymorphism of E-selectin gene is associated with the severity of carotid atherosclerosis, suggesting that genetically-determined alterations in the E-selectin molecule may render ESRD patients with this gene variant particularly susceptible to the detrimental effects of inflammation on the arterial wall.	16554320
Inflammation, Deterioration of lung function	Altered Intercellular Communication	These findings are consistent with the hypothesis that fibrinogen, possibly as a marker for chronic low-grade inflammation, is associated with modest deterioration of lung function in healthy young adults.	16554379
Sepsis, Inflammation	Altered Intercellular Communication	More than 50% showed signs of systemic inflammation indicative of sepsis, reflected by a dramatic increase in serum C-reactive protein and leukocytosis.	16554990
Inflammation, Dyslipidemias, Heart failure, Coronary heart disease	Altered Intercellular Communication	Relationship of adiponectin with markers of systemic inflammation, atherogenic dyslipidemia, and heart failure in patients with coronary heart disease.	16556684
Inflammation, Dyslipidemias, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Serum adiponectin is associated with the presence of atherogenic dyslipidemia and with NT-proBNP concentration but not with markers of systemic inflammation in patients with manifest CHD.	16556684
Inflammation	Altered Intercellular Communication	These MRI findings showed that this ophthlamoplegia was induced by direct viral invasion or extension of inflammation to the ipsilateral cranial nerve.	16562507
Visual Cortex Disorder, Retinitis	Altered Intercellular Communication	The retinal inflammation improved after steroid treatment, but her visual dysfunction remained.	16562510
Inflammation, prostatitis	Altered Intercellular Communication	The degree of prostate inflammation was determined by the extent and degree of inflammation shown by biopsy specimens and is expressed as an inflammation score (range: 0-36).	16563135
prostatitis	Altered Intercellular Communication	Prostate chronic inflammation showed no correlation with PSA concentration (P=0.485, F=0.488).	16563135
prostatitis	Altered Intercellular Communication	However, in contrast to previous reports, there was no correlation between the degree of prostate chronic inflammation and serum PSA concentrations.	16563135
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Chronic inflammation, as indicated by a higher WBC count, may be related with the increased number of components of MS in type 2 diabetic patients.	16563549
helium, Hepatic Encephalopathy, Chronic liver disease	Altered Intercellular Communication	It has been suggested that neurosteroids with agonist properties at the central GABA-A receptor are implicated in the pathogenesis of hepatic encephalopathy (HE) in chronic liver disease.	16563564
Infarction, Inflammation, Neoplasms	Altered Intercellular Communication	The combination of cystic spaces surrounded by oncocytic cells and a poor blood supply makes the tumor susceptible to infarction and inflammation.	16564390
Inflammation, Synovial Membrane	Altered Intercellular Communication	These results suggest that elevated TGF-beta1 in rheumatoid synovial tissue may suppress joint inflammation by inhibiting RANTES secretion from synovial fibroblasts, thus blocking the infiltration of immune cells.	16564576
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Therapeutic administration of Gal-1 or its genetic delivery suppresses chronic inflammation in experimental models of autoimmunity.	16565391
Retinal defect, Degenerative polyarthritis, Osteoporosis	Altered Intercellular Communication	Assuming that NO and PGE2 play a role in cell-cell communication during remodeling, these results suggest that slight differences in mechanotransduction might relate to the opposite bone defects in osteoporosis and osteoarthritis.	16565787
Inflammation	Altered Intercellular Communication	After a deviating stoma procedure, the colonic segment diverted from the faecal stream can develop signs of non-specific inflammation.	16566421
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Interleukin-10 (IL-10) has a key role in regulating mucosal inflammation in inflammatory bowel disease.	16566641
Multiple Organ Failure, Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	Pulse low dose steroids attenuate post-cardiopulmonary bypass SIRS; SIRS I. Cardiopulmonary bypass (CPB) initiates inflammation that contributes to multiorgan dysfunction (SIRS).	16566943
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Serum GHBP levels are markedly reduced in ESRD; this seems to occur independent of nutritional status and may in part be caused by inflammation.	16567271
Heart Diseases, Inflammation, Lung diseases, Diabetes Mellitus	Altered Intercellular Communication	Adjustment for prevalent diseases (including heart diseases, lung disease, and diabetes) associated with inflammation explained less of the association.	16567379
Inflammation	Altered Intercellular Communication	This study suggests that interventions to improve health behaviors, even in old age and especially in low SES groups, may be useful in reducing risks associated with inflammation.	16567379
Inflammation, Intimal proliferation	Altered Intercellular Communication	Histological changes indicative of repair and inflammation were most evident in small sized rotator cuff tears with increased fibroblast cellularity and intimal hyperplasia, together with increased expression of leucocyte and vascular markers.	16567784
Refractory anemias, Inflammation	Altered Intercellular Communication	These findings support the hypothesis that SF ICs and correlated RF production are directly linked to cytokine-dependent inflammation in RA.	16569263
Inflammation, Posterior rhinorrhea, Hypertrophy of adenoids, Nasal obstruction present finding	Altered Intercellular Communication	The following parameters were assessed: nasal obstruction, mucopurulent rhinorrhea, post-nasal drip, adenoidal hypertrophy, tympanic inflammation, tympanogram, rhinomanometry and cultures.	16569351
Inflammation, Hypertrophy of adenoids, Nasal obstruction present finding	Altered Intercellular Communication	Intergroup analysis showed that inhaled tobramycin induced a better improvement versus amoxicillin/clavulanate concerning nasal obstruction (p<0.05), adenoidal hypertrophy (p<0.01), tympanic inflammation (p<0.01), rhinomanometry (p<0.01) and cultures (p<0.05).	16569351
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Mucosa-infiltrated granulocyte neutrophils are an early characteristic of inflammation and the main histological feature of active ulcerative colitis.	16569521
Crohn Disease, Inflammation	Altered Intercellular Communication	Capsule endoscopy findings in patients with suspected Crohn's disease and biochemical markers of inflammation.	16569524
Crohn Disease, Inflammation	Altered Intercellular Communication	Capsule endoscopy has a high diagnostic yield in patients with suspected Crohn's disease and both clinical and biochemical markers of inflammation.	16569524
Inflammation, Acute congestive heart failure	Altered Intercellular Communication	Inflammation and long-term mortality in acute congestive heart failure.	16569545
Inflammation, Acute congestive heart failure, Congestive heart failure	Altered Intercellular Communication	Systemic inflammation has long been recognized as a precipitator of acute congestive heart failure (CHF).	16569545
Inflammation, Congestive heart failure	Altered Intercellular Communication	The impact of inflammation on prognosis in acute CHF, however, is unknown.	16569545
Inflammation, Congestive heart failure	Altered Intercellular Communication	This study evaluated the prognostic role of inflammation among 214 consecutive patients presenting with acute CHF to the emergency department.	16569545
Inflammation, Congestive heart failure	Altered Intercellular Communication	Inflammation is a significant and independent predictor of long-term mortality in patients with acute CHF.	16569545
Inflammation, Thrombosis, Metabolic Syndrome X	Altered Intercellular Communication	The study provides further insight into the relationship between metabolic syndrome, inflammation and thrombosis.	16570157
Inflammation, Amyloidosis	Altered Intercellular Communication	Painful episodic attacks might provoke recurrent acute inflammation, leading to repeated stimulation of acute phase responses and cause secondary amyloidosis.	16570202
Inflammation	Altered Intercellular Communication	Preoperative and intraoperative impressions of non-specific inflammation were accused to be the aetiology.	16570371
Inflammation, immunoglobulin A	Altered Intercellular Communication	Clinical manifestations, small-bowel mucosal morphology, intraepithelial inflammation and TG2-specific extracellular immunoglobulin A (IgA) deposits were investigated in both serum EmA-negative and EmA-positive patients.	16571636
Inflammation, Aortic Valve Insufficiency, Abnormal cardiac conduction, Aneurysm	Altered Intercellular Communication	Inflammation and sclerosis of the aortic root and ventricular septum have been linked to the development of isolated aortic regurgitation and conduction abnormalities; however, aneurysms of the aortic sinuses and coronary arteries have not been previously described.	16572876
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The increased morbidity and mortality of CRC patients was also associated with acute phase response, inflammation, and low serum cholesterol and triglyceride concentration.	16573378
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	In our recent studies, alternative splicing has been shown to have a major role in inflammation and autoimmune muscle diseases.	16574722
Myositis	Altered Intercellular Communication	To examine the novel hypothesis that the expression of an essential alternative splicing factor, alternative splicing factor 2 (ASF/SF2), is modulated in muscle inflammation.	16574722
Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	The effect of smoking on the transcriptional regulation of lung inflammation in patients with chronic obstructive pulmonary disease.	16574938
ARCN1 gene, Inflammation	Altered Intercellular Communication	The imbalance between histone deacetylation and acetylation in favor of acetylation may contribute to the enhanced inflammation in smokers susceptible to the development of COPD.	16574938
Inflammation	Altered Intercellular Communication	These studies demonstrate that patients with DH have evidence of endothelial cell activation in the skin and systemic manifestations of the ongoing inflammation associated with the mucosal immune response.	16575390
Vasculitis	Altered Intercellular Communication	At decreasing blood inflammation parameters and amelioration of the local wound condition the patient could check out after 3 weeks hospitalization.	16575655
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	PsA could be distinguished from OA on the basis of more severe inflammation in the collateral ligaments and the extensor tendons and more severe changes at the corresponding DIP joint entheseal insertions.	16575858
Kimura Disease	Altered Intercellular Communication	Kimura's disease is a fairly uncommon inflammatory condition of unknown etiology.	16579199
Anemia, Kidney Diseases	Altered Intercellular Communication	There is no connection between nephropathy and anemia, and not all of the inflammatory conditions are accompanied with iron metabolism disturbance.	16579333
vascular inflammations, Muscle, Smooth, Vascular	Altered Intercellular Communication	It may also contribute to the vascular inflammation associated with atherogenesis by increasing the synthesis of Interleukin-6 in vascular smooth muscle cells.	16580588
Structure of posterior cerebral artery, Prostate carcinoma, prostatitis	Altered Intercellular Communication	Prostate specific antigen (PSA) is frequently used for prostate cancer (PCa) screening, but serum levels are also increased by prostate inflammation.	16581345
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Elevations in serum levels of alpha1-antitrypsin (ATT), a marker of inflammation, in cancer patients are well documented.	16581345
Inflammation	Altered Intercellular Communication	Inflammation did not increase with repeated injections, despite the increasing ranibizumab doses.	16581423
Inflammatory abnormality of the eye	Altered Intercellular Communication	Mild transient ocular inflammation was the most common postinjection adverse event.	16581423
Intraocular inflammation	Altered Intercellular Communication	Our data suggest that HLA-B27-positive individuals show a higher susceptibility towards development of an intraocular inflammation in the presence of an A allele at nucleotide -238 and, to a lesser degree, at nucleotide -308 of the TNF-alpha gene promoter.	16581430
Inflammation	Altered Intercellular Communication	Acute inflammation was found in one, chronic inflammation and foreign body multinucleated giant cells were seen around the bone wax in 17 sterna.	16581654
Inflammation	Altered Intercellular Communication	Bone wax is non-resorbable and induces chronic inflammation in the operated sternum up to 10 years after application.	16581654
Gastritis, Malignant neoplasm of stomach	Altered Intercellular Communication	H. pylori is a bacterium associated with gastric inflammation and peptic ulcers and is a risk factor for stomach cancer.	16583309
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide (FE(NO)) is considered a marker of airway inflammation and it has been found to be useful for the screening of patients with suspected diagnosis of asthma.	16584881
Inflammation	Altered Intercellular Communication	Although controlled in the mature gut, these antigens may induce inflammation in the developing gastrointestinal tract.	16585287
Inflammatory, Inflammation	Altered Intercellular Communication	Acute inflammation or postinflammatory state and focal infiltration of eosinophils in the lamina propria were the most common abnormalities.	16585287
Cow milk allergy, Dermatitis, Atopic, Inflammation	Altered Intercellular Communication	Atopic eczema and histopathologically confirmed inflammation of the colonic mucosa at presentation were associated with persistence of cow's milk allergy at the age of 1 year.	16585287
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Abnormality of coagulation, Cardiovascular Diseases	Altered Intercellular Communication	Several studies have shown that fibrinolytic and coagulation abnormalities as well as low-grade inflammation predict cardiovascular disease and type 2 diabetes.	16585388
Inflammation, Malignant Neoplasms, Neoplasms	Altered Intercellular Communication	Of these 20 patients, 16 had definite LE (histopathological limbic inflammation, n=6; onconeural antibodies, n=5; voltage-gated potassium channel antibodies, n=3; malignant tumors, n=5), and 4 possible LE because they met the clinical criteria but had no typical antibodies or tumors.	16586118
Inflammation, Hyperamylasemia	Altered Intercellular Communication	Laboratory tests revealed hyperamylasemia and abdominal computed tomography revealed an inflammation of the pancreas and the peripancreas.	16586559
Histiocytosis haematophagic, Hantavirus Infections, Sepsis due to methicillin-sensitive Staphylococcus aureus	Altered Intercellular Communication	He was diagnosed as having secondary hemophagocytosis (HPS) associated with methicillin-sensitive Staphylococcus aureus sepsis due to decubitus inflammation based on bone marrow aspiration and a blood culture.	16595999
Tendinitis, Inflammation, Calcified (qualifier)	Altered Intercellular Communication	5 had synovial proliferation, 2 cases showed loose body, 5 patients revealed markedly increased blood flow consistent with inflammation, 2 patients had triceps tendonitis with calcifications.	16596513
Inflammation	Altered Intercellular Communication	Observations were most apparent for nulliparous women, possibly reflecting an interaction between local inflammation caused by incessant ovulation and increased estrogen exposure on ovarian epithelium.	16596653
Inflammation, Asthma	Altered Intercellular Communication	Small airways inflammation is a recognized pathologic component of asthma, and it is postulated that the observed airway-wall remodeling in small airways could be due to uncontrolled inflammation in airways that are not penetrated by conventional inhaled corticosteroids.	16597076
Inflammatory abnormality of the eye, Glaucoma, CTCAE	Altered Intercellular Communication	Even though glaucoma surgery was necessary in two cases, both ocular inflammation and glaucoma were controlled in all cases.	16597667
Inflammation, Thrombosis, Hepatitis C, FAM126A gene, Cholestasis, Hyperplasia	Altered Intercellular Communication	The findings in the pre-MELD vs. MELD groups were as follows: HCC, 27.5% vs. 48.3% (P = 0.001); portal vein thrombosis (PVT), 13.7% vs. 25.9% (P = 0.08); cholestasis, 16.1% vs. 32.7% (P = 0.026); inflammation grade of 2 or more, 43.7% vs. 48.3% (P = not significant); hepatitis C (HCV), 45.9% vs. 51.7% (P = not significant); HCV with lymphoid aggregates, 25% vs. 60% (P = 0.003); HCV with hyperplastic hilar nodes, 15.0% vs. 36.6% (P = 0.001); and post-LT HCC recurrence, 4.1% vs. 3.4% (P = not significant).	16598742
Inflammation, Asthma	Altered Intercellular Communication	We believe that, in this group of patients, the use of intravenous immunoglobulin perhaps allows the achievement of asthma prevention rather than an amelioration of inflammation.	16598993
Inflammation, Blood Vessel, Elastoid degeneration	Altered Intercellular Communication	The relationships between elastosis, inflammation, congestion of blood vessels and the density range in goblet cell count were determined.	16599316
Inflammation, Loading Technique	Altered Intercellular Communication	Our study support the notion of a low-grade systemic inflammation in older patients with LOAD or VD, characterized by an increase in plasma IL-1beta and TNF-alpha levels.	16600299
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	It is unclear how circulating T cells cross the blood-brain barrier (BBB) and participate in the inflammation process in Alzheimer's disease (AD).	16600437
Inflammation, Cardiovascular Diseases, Diabetes Mellitus	Altered Intercellular Communication	High sensitivity C-reactive protein (CRP) is a marker of acute inflammation recently recognized as an independent predictor of future cardiovascular disease and diabetes.	16600925
Inflammation, Atrophic	Altered Intercellular Communication	Variable increases in immunoreactivity for AKR1C3 was also demonstrated in non-neoplastic changes in the prostate including chronic inflammation, atrophy and urothelial (transitional) cell metaplasia.	16601286
Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Helicobacter pylori infection is the major risk factor for gastric inflammation in the cardia.	16602036
Gastritis	Altered Intercellular Communication	We attempted to clarify the pathogenesis of gastric inflammation in the cardia.	16602036
Inflammation	Altered Intercellular Communication	Cardiac inflammation was also evaluated using magnifying gastroscopy.	16602036
Gastroesophageal reflux disease, Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	We examined Helicobacter pylori infection, gastric juice pH/bile acid (BA), serum pepsinogen and gastrin levels, gastroesophageal reflux disease (GERD), and habitual smoking and assessed the relations between these factors and cardiac inflammation.	16602036
Inflammation	Altered Intercellular Communication	The prevalence of H. pylori infection was statistically higher in patients with cardiac inflammation than in those without inflammation (P < 0.05).	16602036
Inflammation	Altered Intercellular Communication	Cardiac inflammation was linked to low acid output but not linked to the BA concentration or habitual smoking.	16602036
Inflammation	Altered Intercellular Communication	Cardiac inflammation was more pronounced in patients without GERD.	16602036
Inflammation	Altered Intercellular Communication	These results suggest that H. pylori is a major risk factor for cardiac inflammation in the Japanese.	16602036
Stomatitis, Tracheal Stenosis	Altered Intercellular Communication	Magnetic Resonance Imaging of the chest and bronchoscopy revealed severe tracheal stenosis and marked inflammation of tracheal mucosa.	16603056
Inflammation, Granuloma	Altered Intercellular Communication	Histopathology of the lesion showed acute and chronic inflammation and extended ulceration of bronchial mucosa, without granulomas.	16603056
Inflammation, Gastritis, Pangastritis, Intestinal metaplasia, Atrophic	Altered Intercellular Communication	In those patients with gastritis, corpus predominant or pangastritis was commoner in the Japanese (63% Japan v 36% in the UK (chi(2) test, p = 0.003) Atrophy and intestinal metaplasia were more extensive and severe (Mann-Whitney U test, p<0.001) and chronic inflammation and polymorph activity were also greater, especially in the corpus (Mann-Whitney U test, p<0.001).	16603635
Inflammation, Neoplasms	Altered Intercellular Communication	The sheath may need to be opened when surgeon suspects of a tumor, a free disc fragment and any inflammation within the ganglion.	16604353
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterised by pulmonary and systemic inflammation which flare-up during episodes of acute exacerbation (AECOPD).	16606450
ARCN1 gene, Inflammation	Altered Intercellular Communication	Our results reveal abnormalities in TLRs expression in COPD patients and highlight its potential relationship with systemic inflammation in these patients.	16606450
Degenerative polyarthritis, Neurogenic Inflammation	Altered Intercellular Communication	While uncontrolled and derived from small samples, these data suggest that ACET may have a significant anti-inflammatory effect in patients with knee OA, comparable with that achieved with NSAIDs, possibly through an effect on neurogenic inflammation.	16606655
Degenerative polyarthritis, Pain Distress Question, Inflammation	Altered Intercellular Communication	Because many patients with OA improve symptomatically with the use of NSAIDs, it has been widely assumed that the pain of OA is due to synovial inflammation.	16606655
Presenile dementia, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	In the elderly, the most common cause of dementia is Alzheimer disease (AD), which is responsible for the age-related progressive neurodegenerative inflammatory condition mediated by the disease.	16608404
Abscess, pathologic fistula, Inflammation, Short Bowel Syndrome	Altered Intercellular Communication	Recently the conservative intervention are proposed in the treatment of fistulas and abscesses too, but when the inflammation is mild and in patients that underwent to extensive intestinal resection with risk of short bowel syndrome.	16608628
Prostatic fluid, Inflammation, Elastosis perforans serpiginosa	Altered Intercellular Communication	In 8 patients >10 white blood cells/high-power field (WBC/hpf) were found in expressed prostatic secretion (EPS) (Category IIIA), whereas the other 17 had no signs of inflammation (Category IIIB).	16608810
prostatitis	Altered Intercellular Communication	Relation between acute urinary retention, chronic prostatic inflammation and accompanying elevated prostate-specific antigen.	16608815
Inflammation, Prostate	Altered Intercellular Communication	To determine if there is a relationship between acute urinary retention (AUR), the prostate-specific antigen (PSA) level and chronic inflammation of the prostate.	16608815
prostatitis	Altered Intercellular Communication	Chi(2) analysis was used to examine the relationship between prostatic inflammation and AUR.	16608815
prostatitis	Altered Intercellular Communication	Histopathological re-evaluation demonstrated that chronic prostatic inflammation was present in 56% and 37% of the specimens in the AUR and non-AUR groups, respectively (p = 0.014).	16608815
prostatitis	Altered Intercellular Communication	In the AUR group, the mean PSA level was significantly higher in patients with than without prostatic inflammation (7.75+/-5.26 vs 5.07+/-3.21 ng/ml; p = 0.022).	16608815
Acute and chronic inflammation	Altered Intercellular Communication	The odds ratio of AUR for patients with chronic prostatic inflammation and elevated PSA was determined as 4.14 (95% CI 1.65-10.41).	16608815
prostatitis	Altered Intercellular Communication	Multiple linear regression revealed that prostatic inflammation made a significant contribution to AUR.	16608815
prostatitis	Altered Intercellular Communication	Chronic prostatic inflammation may be histopathological evidence of both elevated PSA level and AUR; hence it may play a role in the pathophysiology of AUR.	16608815
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Adult cancer is frequently preceded by a period of prolonged chronic inflammation caused by infectious microbial agents or physical or chemical irritants.	16609014
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation is a central component of progressive chronic kidney disease (CKD).	16609688
Inflammation, Stasis, Esophagitis	Altered Intercellular Communication	Oesophagitis and stasis were assessed by endoscopy and inflammation was graded by histology.	16611281
Inflammation, Stasis	Altered Intercellular Communication	The association between endoscopic food stasis and histological inflammation was significant.	16611281
Inflammation, Esophagitis	Altered Intercellular Communication	The association between endoscopic signs of oesophagitis and histological inflammation was poor.	16611281
Inflammation, Stasis	Altered Intercellular Communication	Because the sensitivity of endoscopy to detect inflammation is low, surveillance endoscopy with biopsy sampling and assessment of stasis is warranted to detect early neoplastic changes.	16611281
Inflammation, SLC9A3R2 gene, Behcet Syndrome	Altered Intercellular Communication	Serum levels of soluble E-selectin, a marker of endothelial activation and inflammation, correlated with levels of serum IgM anti Sip-1 C-ter in patients with Behcet's disease (r = 0.36, P = 0.023).	16611372
Inflammation	Altered Intercellular Communication	These findings suggest that inflammation may play a role in functional decline in persons with and without PAD.	16611704
Inflammation, Blood Vessel	Altered Intercellular Communication	Probably, the chronic inflammation that was documented in these patients may be considered the mechanistic link between serum UA and vascular damage.	16611716
Inflammation, Cerebellum	Altered Intercellular Communication	Histopathology revealed marked loss of cerebral and cerebellar myelin without signs of inflammation.	16611789
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation and activation of immune system cells play an important role in the pathogenesis of atherosclerosis.	16612453
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	YKL-40, a biomarker of inflammation, is elevated in patients with type 2 diabetes and is related to insulin resistance.	16612564
Inflammation, conjunctiva	Altered Intercellular Communication	However, conjunctival infection and anterior chamber inflammation worsened, and another posterior subtenon abscess was found.	16612634
Hematoma	Altered Intercellular Communication	Three weeks postoperatively, there were two superficial skin inflammations and one haematoma.	16612912
Inflammation	Altered Intercellular Communication	Evaluation of IS inflammatory markers in patients with severe BA allowed substantiation of the central role of persistent inflammation as a risk factor of TRBA development.	16613001
Inflammation	Altered Intercellular Communication	A moderate rise of aminotransferases, immunoglobulins, cytokines level indicate weak inflammation in hepatic tissue.	16613099
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Indications of inflammation visualized by ultrasound in osteoarthritis of the knee.	16613309
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Ultrasound examination of a group of patients with osteoarthritis (OA) of the knee for signs of inflammation.	16613309
Degenerative polyarthritis, Inflammation, effusion	Altered Intercellular Communication	The finding in the majority of cases of both effusions on B-mode US and Doppler activity confirms that there is a varying degree of inflammation in knee OA as diagnosed by the ACR criteria.	16613309
Hepatitis A, Hepatitis, FAM126A gene	Altered Intercellular Communication	Patients with HCC and chronic viral hepatitis and patients with chronic viral hepatitis without HCC were compared with patients with liver inflammation of nonviral etiology and with organ donors with healthy livers.	16613328
Hepatitis, Chronic viral hepatitis	Altered Intercellular Communication	The numbers of PDCs and mature MDCs in hepatic LNs of patients with chronic viral hepatitis did not differ from those of patients with liver inflammation of nonviral etiology nor from individuals with healthy livers.	16613328
Xanthogranulomatous inflammation	Altered Intercellular Communication	Two cases were associated with xanthogranulomatous inflammation around bile-like materials, and this inflammatory process extended from ductal lumens to periductal connective tissues.	16613329
Atrophic, prostatitis	Altered Intercellular Communication	The role of IS in the pathogenesis of prostate inflammation and atrophy should be investigated.	16613330
Inflammation	Altered Intercellular Communication	The duodenal biopsies showed villous blunting, chronic inflammation, and decreased to absent goblet cells, Paneth cells, and endocrine cells by histology and electron microscopy.	16613334
Colonic Neoplasms, Inflammation	Altered Intercellular Communication	Inflammation may be involved at the early stage of colon tumor growth.	16614110
Inflammation, Adenocarcinoma of pancreas	Altered Intercellular Communication	Inflammation, genetic polymorphisms in proinflammatory genes TNF-A, RANTES, and CCR5, and risk of pancreatic adenocarcinoma.	16614115
Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Circulating monocytes and plaque macrophages mediate inflammation in the pathogenesis of atherosclerosis.	16614304
Inflammation, Purpura, Thrombotic Thrombocytopenic	Altered Intercellular Communication	Consistent with its role in moderating inflammation, tristetraprolin (TTP, ZFP36) was among the most highly expressed macrophage transcriptional regulators.	16614304
Inflammation, Migraine Disorders	Altered Intercellular Communication	The process of inflammation is crucial in migraine, and several nonsteroidal anti-inflammatory drugs (NSAIDs) are effective in the treatment of migraine attacks.	16614691
Inflammation, Pneumonia	Altered Intercellular Communication	It is considered that CRP, a powerful marker of inflammation, is related with severity of pneumonia and a high level of CRP may be useful to make a decision about hospitalisation.	16615014
Nasal inflammation, Rhinitis	Altered Intercellular Communication	Thirty-nine volunteers were evaluated, 26 without nasal inflammation and 13 with rhinitis.	16615565
Inflammation	Altered Intercellular Communication	The etiology of the lesion is unclear and may be secondary to either sinonasal inflammation or developmental error.	16615604
Inflammation	Altered Intercellular Communication	A rapid and sensitive assay for the quantitation of carboxypeptidase N, an important regulator of inflammation.	16616057
Inflammation, Breast Carcinoma	Altered Intercellular Communication	However, the enhanced levels of nitric oxide may be in response to inflammation in patients with breast cancer.	16616293
Laryngitis	Altered Intercellular Communication	Four-month symptomatic nonresponders (<50% improvement) with continued laryngeal inflammation and normalized esophageal acid exposure were offered laparoscopic Nissen fundoplication.	16616347
Inflammation, diabetic	Altered Intercellular Communication	Effect of a diet and exercise intervention on oxidative stress, inflammation and monocyte adhesion in diabetic men.	16616795
Airway structure, ARCN1 gene	Altered Intercellular Communication	U-II may act locally, or, via paracrine or autocrine way, play a role in the mechanism of the airway inflammation and airway remodeling in COPD.	16617357
Inflammation	Altered Intercellular Communication	The parotid gland is the salivary gland most commonly affected by inflammation.	16618667
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Chronic intraprostatic inflammation is suspected to play a role in the pathogenesis of prostate cancer.	16618781
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Polymorphisms in cytokine genes can influence inflammation and immune response and may be related to the risk of prostate cancer.	16618781
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Markers of eosinophilic inflammation and risk prediction in patients with coronary artery disease.	16620281
vascular inflammations, Coronary Artery Disease	Altered Intercellular Communication	In vitro and clinical studies suggest that eotaxins could play a role in vascular inflammation, but no data are available on their prognostic significance in patients with angiographically documented coronary artery disease (CAD).	16620281
Inflammation	Altered Intercellular Communication	Systemic inflammation is well correlated with CS temperature; thus, an inflammatory process could be the underlying mechanism for increased heat production from the myocardium.	16620282
Inflammation	Altered Intercellular Communication	Pancreatic disseminated inflammation was verified pathologically in these cases.	16620641
Icterus, Pancreatitis	Altered Intercellular Communication	There exists a direct relationship between the jaundice and the pancreatic inflammation.	16620641
Impaired cognition	Altered Intercellular Communication	There is growing evidence in the neuropsychological literature that growth hormone (GH) deficiency is associated with cognitive impairment.	16621325
Nephritis	Altered Intercellular Communication	Prednisone (20 mg/day) was administered for renal inflammation.	16622725
Inflammation, Bursitis, Hypertrophy	Altered Intercellular Communication	Magnetic resonance imaging showed enlargement and inflammation of the psoas muscle at the same side of iliopsoas bursitis.	16622726
Inflammation	Altered Intercellular Communication	Granulomatous inflammation of the bone was confirmed pathologically.	16623262
Excessive tearing, Inflammation, Nasolacrimal Duct Obstruction	Altered Intercellular Communication	We describe our experience in treating epiphora caused by chronic inflammation and obstruction of the nasolacrimal system by endonasal placement of a polyurethane stent in the nasolacrimal duct, with long-term assessment of patency (4 years).	16623311
Inflammatory abnormality of the eye	Altered Intercellular Communication	Two cases of ocular inflammation, one with a medical history of systemic TB and the other, with that of presumed systemic TB, were examined.	16625271
Necrotizing granulomatous inflammation, Vasculitis, CTCAE, Systemic Vasculitis, Necrotizing glomerulonephritis	Altered Intercellular Communication	Microscopic polyangiitis (MPA) is a systemic necrotizing vasculitis affecting small vessels without necrotizing granulomatous inflammation and is commonly associated with necrotizing glomerulonephritis.	16625340
Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	Laboratory examinations showed severe inflammation and acute progressive renal failure.	16625340
Hair follicle structure, Alopecia	Altered Intercellular Communication	Depending on the genetic background, hormonal microenvironment in the scalp and conditioning of individual hair follicle bio-responses, female and male patterned hair loss may end up into different phenotypes.	16626380
Lymphomatoid Papulosis, Granulomatous inflammation	Altered Intercellular Communication	Four cases were compatible with lymphomatoid papulosis (LyP) based on the clinical course, which was recurrent asymptomatic papular nodular lesions over years responding to methotrexate; granulomatous inflammation and lack of other inflammatory cell elements were characteristic.	16627259
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	No significant differences were noted between baseline microscopic features of synovial tissue inflammation in patients with rheumatoid arthritis and in those with non-rheumatoid arthritis (ie, all diagnoses other than rheumatoid arthritis).	16627543
Inflammation	Altered Intercellular Communication	The observations support the view that intra-articular treatment either with 90Y and glucocorticoids or with glucocorticoids alone is especially successful in patients with marked synovial inflammation.	16627543
Inflammation, Coronary heart disease	Altered Intercellular Communication	Lipoprotein-associated phospholipase A2 predicts future cardiovascular events in patients with coronary heart disease independently of traditional risk factors, markers of inflammation, renal function, and hemodynamic stress.	16627803
Inflammation, Asthma	Altered Intercellular Communication	C(alv) may possibly reflect alveolar inflammation in asthma.	16627868
Neurotoxicity Syndromes, Data types - Address	Altered Intercellular Communication	Our results indicate that in AD there are high levels of expression of the neurotoxic protease thrombin and the inflammation-associated proteins IL-8 and alphaVbeta3 and alphaVbeta5 integrins.	16627934
Inflammation	Altered Intercellular Communication	It has already been demonstrated that insulin resistance (IR) is associated with the stimulation of erythroid progenitors and with increased levels of inflammation markers.	16628283
Mapuche Language, Orbital Pseudotumor, Unspecified visual loss	Altered Intercellular Communication	A 49-year-old immunocompetent woman presented with unilateral painful orbital inflammation associated with deep visual loss due to ARN.	16628421
Intraocular inflammation, Orbital Pseudotumor	Altered Intercellular Communication	Orbital inflammation resolved rapidly after the initiation of antiviral drugs, whereas intraocular inflammation worsened.	16628421
Mapuche Language, Orbital Pseudotumor	Altered Intercellular Communication	Consequently, ARN should be investigated in all patients with orbital inflammation, in order to initiate immediately an appropriate antiviral strategy.	16628421
Inflammation	Altered Intercellular Communication	However, although DEP induce IgE synthesis, little is known of their role on T-cell activation, the main cells orchestrating asthma inflammation.	16629788
Granulomatous inflammation	Altered Intercellular Communication	The presence of lichenoid or granulomatous inflammation in an oral mucosal biopsy usually suggests a distinct range of diagnostic possibilities.	16630288
Necrotizing granulomatous inflammation, Inflammation	Altered Intercellular Communication	Microscopically the lesions were characterized by the presence of lichenoid inflammation with concomitant granulomatous inflammation.	16630288
Bradyarrhythmia (disorder), Inflammation, Heart Block, Bradycardia, Tachyarrhythmia	Altered Intercellular Communication	(3) Acute inflammation changes in the CCS corresponded to tachyarrhythmia and multiple ventricular premature beats, whereas chronic inflammation and degenerative changes in the CCS were often related to bradyarrhythmia, bradycardia-tachycardia syndrome and conduction block.	16630457
Inflammation, Data types - Address	Altered Intercellular Communication	Because scFvs lack the Fc portion of the immunoglobulin molecule, human scFvs against Abeta may be useful to treat AD patients without eliciting brain inflammation.	16630540
Inflammation, Tissue injury	Altered Intercellular Communication	C-reactive protein (CRP) is a sensitive marker for inflammation and tissue injury.	16630759
Inflammation, Helicobacter pylori, Esophagitis, Chronic gastritis	Altered Intercellular Communication	Cases (n=46) with concurrent mucosal biopsies of the duodenum, stomach, and esophagus were divided into 4 groups: I, no inflammation in any site; II, active esophagitis only; III, chronic active gastritis only, with Helicobacter pylori bacteria; IV, chronic gastritis only, without H pylori bacteria.	16630772
Inflammation	Altered Intercellular Communication	There was no correlation between the number of duodenal IELs and severity of inflammation, patient age or sex, or symptoms.	16630772
Inflammation	Altered Intercellular Communication	This finding may reflect an underlying mechanism of diffuse inflammation in the gastrointestinal tract.	16630772
Inflammation, MS4A2 wt Allele	Altered Intercellular Communication	Vascular endothelial growth factor (VEGF) has been suggested to be a key mediator in the development of atopy and T(H)2 inflammation.	16630933
Inflammation	Altered Intercellular Communication	IL-17F is a recently discovered cytokine that plays a role in tissue inflammation by inducing release of proinflammatory and neutrophil-mobilizing cytokines.	16630936
Inflammation	Altered Intercellular Communication	The evidence that inflammation is an important mechanism in atherogenesis is growing.	16630992
Myocarditis, CTCAE 5.0, Myocardial, Myocarditis	Altered Intercellular Communication	Although CE-CMR has been revealed to be effective in identifying areas of myocardial damage in acute myocarditis, its role in the diagnosis of chronic myocardial inflammation has not yet been investigated.	16631005
Myocarditis, Certified Midwife	Altered Intercellular Communication	Contrast-enhanced cardiac magnetic resonance identified areas of myocardial inflammation in up to 70% of patients with biopsy-proven CM.	16631005
Myocarditis	Altered Intercellular Communication	The effect of EPO on myocardial inflammation, however, has not yet been clarified.	16631620
Myocarditis	Altered Intercellular Communication	These results may suggest that EPO ameliorated the progression of EAM by modulating myocardial inflammation and apoptosis.	16631620
Pneumonia, Pneumonitis, CTCAE, Granulomatous inflammation, Fibrosis Assessment, Hamartoma	Altered Intercellular Communication	Pathologic diagnoses from the pulmonary resections revealed granulomatous inflammation in 91 patients (65%), hamartoma in 17 patients (12%), pneumonia or pneumonitis in 14 patients (10%), fibrosis in 5 patients (4%), and other in 13 patients (9%).	16631679
Inflammation, Periodontitis, Malnutrition	Altered Intercellular Communication	Does periodontitis reflect inflammation and malnutrition status in hemodialysis patients?	16632020
Chronic infectious disease, Periodontitis, Inflammation, Atherosclerosis	Altered Intercellular Communication	Chronic infection and inflammation, including periodontitis, is linked to an increased risk for atherosclerosis.	16632020
Inflammation, Malnutrition	Altered Intercellular Communication	Parameters of malnutrition and inflammation also were associated with poor periodontal status.	16632020
Inflammation, Periodontitis, Malnutrition	Altered Intercellular Communication	According to the severity of periodontitis, there were higher percentiles of patients with malnutrition (chi-square = 13.055; P = 0.005) and inflammation (chi-square = 10.046; P = 0.018) in the severe group.	16632020
Inflammation, Malnutrition	Altered Intercellular Communication	Periodontal health is poor in hemodialysis patients and correlates with markers of malnutrition and inflammation.	16632020
Crohn Disease, Inflammation	Altered Intercellular Communication	Crohn's disease is a condition of chronic inflammation potentially involving any location of the alimentary tract from mouth to anus.	16632987
Conjunctivitis	Altered Intercellular Communication	Slit-lamp examination showed a central defect in the right corneal epithelium with underlying stromal opacification, only mild conjunctival inflammation with slight decreased tear production, and otherwise apparently normal eyes.	16633039
Keratitis	Altered Intercellular Communication	Biopsy of the erythematous conjunctiva adjacent to the area of corneal inflammation showed the presence of mast cells.	16633043
Inflammatory Bowel Diseases, Inflammation, Diverticular Diseases	Altered Intercellular Communication	For all IBD diagnoses, more sigmoid inflammation occurred in cases with diverticular disease: 82% versus 65% for controls (P = 0.005), and in the rectum: 85% versus 69% for controls (P = 0.005).	16633104
Crohn Disease, Inflammation, Diverticulosis	Altered Intercellular Communication	In the Crohn's disease with diverticulosis subset, sigmoid inflammation was more common: 70% versus 42% for controls (P = 0.007), and in the rectum: 70% versus 46% for controls (P = 0.02).	16633104
Inflammatory Bowel Diseases, Inflammation, Diverticulosis	Altered Intercellular Communication	We observed an increased frequency of sigmoid and rectal inflammation, EIMs, and an older age of IBD onset in cases with diverticulosis.	16633104
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Inflammation and coagulation play pivotal roles in host defence.	16633958
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	As phylogenetically old responses, there is extensive cross-talk between inflammation and coagulation in enabling an adequate immune response against potentially injurious stimuli.	16633958
Inflammation, Observation Method - Coagulation, Disease	Altered Intercellular Communication	Understanding the mechanisms involved in the crosstalk between inflammation and coagulation may yield new therapeutic strategies for human diseases.	16633958
Vasculitis, Hyperhomocysteinemia, Observation Method - Coagulation, Peripheral arterial occlusive disease	Altered Intercellular Communication	These results provide evidence against a major effect of hyperhomocysteinaemia on vascular chronic inflammation or coagulation in patients with symptomatic peripheral arterial occlusive disease.	16634837
Pneumonitis	Altered Intercellular Communication	The authors also measured exhaled carbon monoxide, another marker of lung inflammation.	16635093
Pneumonitis, Asbestosis	Altered Intercellular Communication	FENO is raised in asbestosis consistent with lung inflammation, and also in pleural plaques.	16635093
Airway structure, Colonization	Altered Intercellular Communication	Relationship among bacterial colonization, airway inflammation, and bronchodilator response in patients with.	16635414
Inflammation	Altered Intercellular Communication	Monoclonal lymphoid populations evolving from chronic inflammation in the urinary tract may be the source of the amyloid AL proteins.	16635518
Inflammation, Thrombosis, Takayasu Arteritis, Arteritis	Altered Intercellular Communication	Inflammation and thrombosis are closely related processes, but the association between disease activity and thrombogenicity in Takayasu's arteritis (TA) is poorly understood.	16636497
Inflammation, Perforation (observation), Peritonitis	Altered Intercellular Communication	During the operation under general anesthesia was found a phlegmonous inflammation of a Mekel diverticulus with perforation as well as local peritonitis and a catharal inflammation of the appendix.	16637307
Inflammation, Neoplasms	Altered Intercellular Communication	A case of a male who was admitted for post-operative control of brain tumor exeresis and who had preauricular and submaxillary inflammation after a routinely performed tracheostomy is presented.	16637429
Hypogonadism	Altered Intercellular Communication	We discuss the hormonal and histopathologic changes in our patient and postulate that the association of CED with hypogonadism could be attributable to the impaired regulation of gonadal growth and steroidogenesis, in which TGF-b 1 has an important role.	16638728
Heart failure	Altered Intercellular Communication	Moreover, hormonal alterations related to the heart failure syndrome were related to increased protein oxidation.	16639065
Inflammation, Pancreatitis	Altered Intercellular Communication	Relapsing pancreatitis is characterized by repeated episodes of acute inflammation of the pancreas, with either a localized or a systemic organic response that may progress to chronic pancreatitis.	16639073
Necrotizing granulomatous inflammation, Necrosis	Altered Intercellular Communication	The subsequent biopsy from the left inferior fornix and the skin showed histopathologically a granulomatous epitheloid cell inflammation without central necrosis and without acid-proof bacilli.	16639672
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	In Crohn's disease, abnormal activation of mucosal T lymphocytes against enteric bacteria is the key event triggering intestinal inflammation.	16641137
Inflammation, Neoplasms	Altered Intercellular Communication	Its expression was associated with invasion, inflammation, apoptotic and well-differentiated areas of the tumors, but not with cell proliferation.	16641547
Inflammation	Altered Intercellular Communication	Our results suggest that during esophageal tumorigenesis, MMP-21 and MMP-26 have different, unique expression patterns both being tightly regulated and induced in the vicinity of inflammation.	16641547
Ventricular Dysfunction, Heart Failure, Systolic	Altered Intercellular Communication	Whether brain natriuretic peptide (BNP), a neurohormone marker of ventricular dysfunction, correlates with an enhanced ventilatory response (EVR) during cardiopulmonary exercise test, a well-known predictor of prognosis, in systolic heart failure (HF) is currently unknown.	16641874
Inflammation, Thickened	Altered Intercellular Communication	The aorta and its major branches including the carotid arteries, however, were free of inflammation and thickening.	16642350
Inflammation, Thrombosis, Communicable Diseases, Heart Diseases, Malignant Neoplasms	Altered Intercellular Communication	The primary patient conditions (48 male and 32 female, mean age, 51 years) were malignancy (n = 29), infection (n = 25), inflammation (n = 6), heart disease (n= 3), thrombosis (n = 2), injury (n = 2), and other miscellaneous conditions (n = 13).	16642548
Inflammation, Thrombophlebitis migrans, Ulcer	Altered Intercellular Communication	Typical manifestations include urogenital ulcerations, eye inflammation and migratory thrombophlebitis.	16642662
Inflammation, Malnutrition	Altered Intercellular Communication	Malnutrition and inflammation are common in hemodialysis (HD) patients, and are usually closely associated.	16642663
Inflammation, Malnutrition	Altered Intercellular Communication	Serum C-reactive protein (CRP) concentrations have been found to be significantly elevated in hemodialysis patients and reflects chronic inflammation, and as an acute-phase reactant, is a sensitive and independent marker of malnutrition.	16642663
HD Term Type, Hyperparathyroidism, Inflammation, Hyperphosphatemia, CTCAE	Altered Intercellular Communication	The positive correlation of high serum iPTH with inflammation implies further need to control hyperphosphatemia and secondary hyperparathyroidism in HD patients, also inverse correlation of serum CRP with cholesterol and triglyceride further support the malnutrition-inflammation complex syndrome (MICS) which frequently seen in hemodialysis patients (Tab.	16642663
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Histological evidence of prostate cancer, acute inflammation, chronic inflammation, and benign prostatic tissue were noted in biopsy cores, together with the associated f/tPSA values.	16643488
Acute inflammation, Chronic inflammation, Prostate carcinoma	Altered Intercellular Communication	Men with acute inflammation (27/175, 15%) had significantly lower serum f/tPSA values (mean 13.4%) than those with chronic inflammation (mean 16.6%, P = 0.002) and benign prostatic tissue (mean 15.7%, P = 0.034), but were similar to men with prostate cancer (mean 15.3%, P = 0.315).	16643488
Inflammation, Acute inflammation	Altered Intercellular Communication	In this prospectively screened cohort of men, there was a high incidence of asymptomatic inflammation on prostatic histology; f/tPSA values were significantly lower in men with acute inflammation.	16643488
Inflammation	Altered Intercellular Communication	The 5-HT(1B/1D) receptor agonist may inhibit neurogenic inflammation and vasodilation near the irritated trigeminal root.	16643550
Inflammation	Altered Intercellular Communication	Ureteral stent should be placed in only cases of severe inflammation of the ureter or inappropriate suturing.	16643610
Inflammation, Urethritis	Altered Intercellular Communication	This study suggests that symptoms and signs are a surrogate marker for the degree of inflammation present, and that as urethral inflammation increases, the likelihood of detecting a sexually transmitted pathogen also increases.	16643676
prednisone	Altered Intercellular Communication	In 11 cases with severe inflammation prednisone was administered during radiotherapy.	16643752
Inflammation, Weight decreased, Fever, CTCAE	Altered Intercellular Communication	A 54-year-old woman presented with fever and weight loss for 7 months and laboratory findings suggestive of inflammation.	16643995
Granulomatous inflammation	Altered Intercellular Communication	Histopathologic examination revealed granulomatous inflammation with central caseous necrosis in all patients.	16644403
Communicable Diseases, Inflammation	Altered Intercellular Communication	We hypothesized that burden of infection could be associated with chronic low-grade inflammation, resulting in insulin resistance.	16644637
Inflammation	Altered Intercellular Communication	It has been postulated that inflammation deteriorates the lipid profile, thereby increasing cardiovascular risk.	16644785
Inflammation, Chronic antral gastritis	Altered Intercellular Communication	Body:antral chronic gastritis ratio and body:antral combined inflammation ratio (both with CC = 0.49) and age (CC = 0.44) were also inversely correlated with MAO.	16644877
Malignant neoplasm of gastrointestinal tract	Altered Intercellular Communication	The relationship between an inflammation-based prognostic score (Glasgow Prognostic Score) and changes in serum biochemical variables in patients with advanced lung and gastrointestinal cancer.	16644880
Primary malignant neoplasm	Altered Intercellular Communication	The Glasgow Prognostic Score (GPS), an inflammation-based prognostic score formed from standard thresholds of C reactive protein (CRP) and albumin, has prognostic value in patients with advanced cancer.	16644880
Inflammation, Malnutrition	Altered Intercellular Communication	There may be no advantage in replacing the CG equation by the MDRD equation except for patients with severe malnutrition and/or inflammation.	16645231
Inflammation, bone destruction	Altered Intercellular Communication	The decrease in inflammation attributed to intraarticular corticosteroids is accompanied by down-modulation of bone destruction markers.	16646024
Inflammation, Myopathy	Altered Intercellular Communication	The predominant myopathologic findings are active myopathy, C5b-9 staining of endomysium, focal perivascular and perimysial inflammation, often with a prominent B cell component, and endomysial dendritic cells.	16646041
Inflammation	Altered Intercellular Communication	This study demonstrates that a long-standing chronic inflammation leads to deposition of collagens type I , III and IV under the damaged epithelium, resulting in an increasingly thick sub-basement membrane layer.	16646240
Inflammation, Thyroid associated opthalmopathies	Altered Intercellular Communication	Imaging of inflammation in Graves' ophthalmopathy by positron emission tomography/computed tomography.	16646690
thromboembolic, Inflammatory abnormality of the eye, Cataract, Hemorrhagic, Cessation of life, Hypertension, CTCAE, Glaucoma, CTCAE	Altered Intercellular Communication	There was no evidence of an increase in deaths, in events associated with systemic VEGF inhibition (e.g., hypertension, thromboembolic events, serious hemorrhagic events), or in severe ocular inflammation, cataract progression, or glaucoma in pegaptanib-treated patients relative to sham-treated patients.	16647134
Inflammation, Anemia	Altered Intercellular Communication	Living kidney donation: anemia and inflammation in the early postoperative period.	16647436
Microalbuminuria, Inflammation, Atherosclerosis	Altered Intercellular Communication	Microalbuminuria (MA) and low-grade inflammation constitute emerging markers of subclinical atherosclerosis.	16647614
Inflammation, Intracranial Aneurysm	Altered Intercellular Communication	An important part is played by inflammation in intracranial aneurysm formation.	16648144
Asthma	Altered Intercellular Communication	The reasons are unknown; although it has been hypothesized that hormonal factors may explain this sex-dependent risk of adult-onset asthma.	16650045
Perifolliculitis	Altered Intercellular Communication	Biopsies taken from FFA patients showed less follicular inflammation and more apoptotic cells than those from LPP patients.	16650161
Neurodegeneration due to 3-hydroxyisobutyryl coenzyme A hydrolase deficiency, Dopa-Responsive Dystonia, Dystonia Disorders	Altered Intercellular Communication	This classification is important to improve the awareness of clinicians that more than one metabolic defect can underlie the phenotype of a DOPA-responsive dystonic disorder and that dystonia should always trigger a rapid diagnosis of the underlying neurotransmitter synthesis defect, in view of the excellent treatability of a DRD.	16650784
Adenocarcinoma Of Esophagus	Altered Intercellular Communication	Observational studies suggest that nonsteroidal anti-inflammatory drugs (NSAIDs) reduce the risk of esophageal adenocarcinoma, but it is not known at what stage they may act in the esophageal inflammation-metaplasia-adenocarcinoma sequence.	16651456
Inflammation, Thrombosis, Observation Method - Coagulation, Venous Thromboembolism, vinyltriethoxysilane	Altered Intercellular Communication	Candidate genes in inflammation, thrombosis, coagulation, and lipid metabolism pathways have been implicated in venous thromboembolism (VTE).	16651467
Inflammation, Rupture, Cerebrovascular accident	Altered Intercellular Communication	Dense plaque inflammation (especially infiltration with macrophages) was the feature most strongly associated with both cap rupture (odds ratio 3.39, 95% confidence interval 2.31 to 4.98, P<0.001) and time since stroke (P=0.001).	16651471
Rupture, Inflammation, Dental Plaque, Cerebrovascular accident	Altered Intercellular Communication	Strong negative associations with time since stroke were also seen for cap rupture (P=0.02), overall plaque inflammation (P=0.003), and "unstable plaque" (P=0.001).	16651471
Inflammation, Tacca leontopetaloides, Dental Plaque, Cerebrovascular accident	Altered Intercellular Communication	Although plaques removed < or =60 days after the most recent event were more unstable after a stroke than after a TIA, the instability persisted after a TIA, and plaques removed >180 days after most recent event were less unstable after a stroke than after a TIA (plaque inflammation: < or =60 days, odds ratio 2.33 [95% confidence interval 0.76 to 7.19]; >180 days, 0.36 [0.16 to 0.84]; P=0.008; unstable plaque: odds ratio 3.27 [95% confidence interval 0.93 to 11.50] versus 0.74 [0.33 to 1.69], P=0.05).	16651471
Inflammation, Tacca leontopetaloides, Cerebrovascular accident	Altered Intercellular Communication	The tendency for plaque inflammation and overall instability to persist with time after a TIA but to decrease with time after a stroke suggests that the nature of the underlying pathology may differ.	16651471
Juvenile arthritis, Inflammation	Altered Intercellular Communication	Because the serum COMP concentration was decreased in cases of systemic JIA in which growth impairment was pronounced, the systemic inflammation occurring in systemic JIA may have an effect on cartilage turnover, which plays an important role in growth.	16652429
vascular inflammations, Atherosclerosis, Peripheral arterial occlusive disease	Altered Intercellular Communication	Markers of vascular inflammation are associated with the extent of atherosclerosis assessed as angiographic score and treadmill walking distances in patients with peripheral arterial occlusive disease.	16669409
Inflammation, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	The importance of inflammation in atherosclerosis is well established in cardiovascular disease.	16669409
vascular inflammations, Peripheral arterial occlusive disease	Altered Intercellular Communication	However, limited data exist on the relationship between vascular inflammation and the severity of peripheral arterial occlusive disease (PAD).	16669409
vascular inflammations	Altered Intercellular Communication	These findings indicate that vascular inflammation is implicated in PAD, which might be of importance in future diagnosis and treatment of the disease.	16669409
Inflammation	Altered Intercellular Communication	Synovial inflammation was assessed by measuring time-dependent enhancement rates (E-rate) from dynamic MRI scans and technetium(99m)-labelled nanocolloid ((99m)Tc-NC) uptake from scintigraphy scans.	16670155
Inflammation, Wrist joint	Altered Intercellular Communication	The degree of local synovial inflammation at baseline, evaluated by dynamic and static MRI and quantitative NC scintigraphy, is closely related to the progression of wrist joint erosions during the first 2 yrs of the disease.	16670155
Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is characterized by chronic intestinal inflammation as a result of an exaggerated T cell response.	16670525
Gastrointestinal inflammation	Altered Intercellular Communication	Probiotic treatment may be effective in diseases involving gut microflora and intestinal inflammation.	16670529
Gynecomastia	Altered Intercellular Communication	After surgery, the gynecomastia has completely disappeared and hormonal alterations returned to normal.	16671273
Inflammatory abnormality of the eye	Altered Intercellular Communication	The initial dose of IFNalpha was 6 MU/day in 37 patients (84.1%) and 3 MU/day in 7 patients (15.9%), and was gradually tapered after ocular inflammation was suppressed.	16673135
Inflammation, Vascular System Injuries	Altered Intercellular Communication	Platelet stimulation and activation are known not only as prerequisite of clot formation but are increasingly recognized as important contributors to inflammation and vascular injury.	16675725
Inflammation, Thrombosis	Altered Intercellular Communication	Association of advanced glycoxidation end products and inflammation markers with thrombosis of arteriovenous grafts in hemodialysis patients.	16675897
HD Term Type, Inflammation, Intimal proliferation	Altered Intercellular Communication	These results support an association between circulating AGEs, markers of inflammation and endothelial function and intimal hyperplasia at the venous anastomosis of AVGs in HD patients.	16675897
Pancreatitis, Acute, Inflammation	Altered Intercellular Communication	We studied whether procalcitonin, a marker of systemic inflammation, is important in the differential diagnosis of patients with mild and severe acute pancreatitis.	16676250
Suppuration, Inflammation, Biliary calculi	Altered Intercellular Communication	Multiple reports in the literature confirm that retained gallstones spilled during laparoscopic cholecystectomy perpetuate chronic inflammation and suppuration long after the initial operation.	16676851
Achalasia, Inflammation	Altered Intercellular Communication	The histopathological investigations of the esophageal wall in 17 patients undergoing esophageal resection or myotomy for achalasia suggest that the reduction of intramural ganglion cells might be a secondary change, probably due to inflammation triggered by autoimmune mechanisms or a chronic degenerative process of the central and/or peripheral part of the vagal nerve.	16677160
2,3-Cyclic-Nucleotide Phosphodiesterases", Granulomatous inflammation, Aspergillus, Necrosis	Altered Intercellular Communication	The histological feature of CNPA included the presence of tissue invasion by Aspergillus, tissue necrosis and granulomatous inflammation.	16677449
Incontinence, Structure of pudendal nerve	Altered Intercellular Communication	Reasons for the development of incontinence might be surgery including pudendal nerve damage, hormonal reasons and ageing.	16678333
Inflammation, Coronary Artery Vasospasm	Altered Intercellular Communication	In conclusion, the results of this study suggest that inflammation can exist in coronary vasospasm without hemodynamically significant CAD.	16679078
Inflammation	Altered Intercellular Communication	Relations of inflammation and novel risk factors to valvular calcification.	16679093
Inflammation	Altered Intercellular Communication	Investigators have suggested that inflammation may play a role in the pathogenesis of valve calcium.	16679093
Inflammation, Hemorrhage, Meckel Diverticulum, Intestinal Obstruction	Altered Intercellular Communication	A variety of complications are related to a Meckel's diverticulum, including hemorrhage, intestinal obstruction and inflammation.	16680236
Airway structure	Altered Intercellular Communication	Lower serum ECP levels, a surrogate measure of airway inflammation, were associated with improvements in lung function.	16680924
Eyelid Neoplasms, Malignant neoplasm of skin of eyelid	Altered Intercellular Communication	There were 53 (17.8%) inflammatory conditions, 212 (71.4%) benign eyelid tumors and 32 (10.8%) malignant eyelid tumors.	16681045
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Different patterns of inflammation and prognosis in invasive carcinoma of the breast.	16681685
Inflammation, Breast Carcinoma, Neoplasms	Altered Intercellular Communication	Inflammation in carcinoma of the breast may represent an immune response to the tumour, but there is evidence that this response is impaired.	16681685
Inflammation, Neoplasms	Altered Intercellular Communication	Inflammation may also stimulate tumour growth by releasing proteolytic enzymes and angiogenic factors.	16681685
Inflammation, Neoplasms	Altered Intercellular Communication	On multivariate analysis of women with stage 1 and 2 tumours (n = 679, median follow-up of 9.8 years), survival was independently associated with diffuse inflammation (relative risk 0.43, 95% confidence interval 0.24, 0.77, P =0.005) in addition to histological grade, axillary lymph node status, tumour size and oestrogen receptor status.	16681685
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	To investigate the association of pit patterns as assessed by magnifying colonoscopy (MCS) with histological inflammation and mucosal chemokine activity in patients with quiescent ulcerative colitis, and to prospectively analyse the prognostic factors that may predict exacerbations.	16682428
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	MCS grading is associated with the degree of histological inflammation and mucosal IL8 activity in patients with quiescent ulcerative colitis, and may predict the probability of subsequent disease relapse in patients with ulcerative colitis in remission.	16682428
Inflammation	Altered Intercellular Communication	Histopathological examination of the discolorated gingivae showed the presence of non-specific inflammation with a foreign body.	16683412
Inflammation	Altered Intercellular Communication	These data suggest a previously unrecognized mechanism through which inflammation may worsen cardiovascular outcomes.	16684119
Cystic Fibrosis, Inflammation, cinobufotalin, Bronchitis	Altered Intercellular Communication	Polymorphonuclear neutrophil (PMN)-dominated inflammation is prominent in the airways of subjects with cystic fibrosis (CF) and chronic bronchitis (CB).	16685004
Inflammation	Altered Intercellular Communication	Interleukin (IL)-8, myeloperoxidase (MPO), and DNA are markers of neutrophilic inflammation.	16685004
Airway structure, Allergic asthma	Altered Intercellular Communication	Airway inflammation and cellular stress in noneosinophilic atopic asthma.	16685009
Airway structure, ARCN1 gene, Asthmatic pulmonary eosinophilia	Altered Intercellular Communication	The aim of our study was to test the hypothesis that airway inflammation in NEA patients is different from that seen in patients with eosinophilic asthma (EA) and is similar to COPD.	16685009
Airway structure, ARCN1 gene	Altered Intercellular Communication	Despite low eosinophil counts, airway inflammation in NEA patients may share common features with that in EA patients but is distinct from COPD.	16685009
Inflammation, Asthma	Altered Intercellular Communication	Larger studies are needed to investigate further the clinical and inflammatory characteristics of NEA before we are able to categorize asthma patients into those with or without eosinophilic inflammation.	16685009
Pleurisy	Altered Intercellular Communication	Ang-2 levels but not Ang-1 levels are elevated in exudative PEs, and they correlate with levels of VEGF and markers of pleural inflammation.	16685017
Pleurisy	Altered Intercellular Communication	It is thus possible that Ang-2 along with VEGF participate in pleural inflammation and the pathogenesis of exudative PEs.	16685017
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Consumption of coffee, a major source of dietary antioxidants, may inhibit inflammation and thereby reduce the risk of cardiovascular and other inflammatory diseases in postmenopausal women.	16685044
Inflammation, Calcification of coronary artery	Altered Intercellular Communication	Coronary artery calcification, systemic inflammation markers and mineral metabolism in a peritoneal dialysis population.	16685142
Inflammation, Disturbance	Altered Intercellular Communication	Our results indicate that conditions such as inflammation and mineral disturbances are associated with its development.	16685142
Inflammation, Chronic sinusitis, Allergic fungal sinusitis	Altered Intercellular Communication	Th2 immunological inflammation in allergic fungal sinusitis, nonallergic eosinophilic fungal sinusitis, and chronic rhinosinusitis.	16686376
Inflammation, Gland	Altered Intercellular Communication	There was a significant stepwise decrease in density of ghrelin-positive cells, with progression of histological severity of chronic inflammation, neutrophil activity and glandular atrophy in the corpus.	16687031
Inflammation, Gland, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Impaired density of gastric ghrelin-positive cells is associated with neutrophil activity, chronic inflammation and glandular atrophy induced by H. pylori infection.	16687031
Inflammation	Altered Intercellular Communication	Moderate self-reported weight increase, and body fat accumulation, suggesting long-term positive energy balance is associated with muscle DNA oxidative injury and inflammation.	16687193
Inflammation	Altered Intercellular Communication	Skin biopsy showed acute and chronic inflammation with an abscess that contained "yeast" (Figure 3).	16687984
Inflammation, Skin lesion	Altered Intercellular Communication	The patient was started on a 6-month course of itraconazole oral solution with slow resolution of her joint inflammation and skin lesions over the next several weeks.	16687984
Inflammation, Dysplasia, Infection caused by Helicobacter pylori, Neoplasms, Edema, Gastritis, Atrophic, Intestinal metaplasia, Foveolar hyperplasia, Polyposis, Gastric	Altered Intercellular Communication	The histologic alterations observed from tissues collected during endoscopic examination were: chronic inflammation in 75 cases (84.06%), foveolar hyperplasia in 36 cases (40.44%), intestinal metaplasia in 31 cases (34.83%), acute inflammation in 16 cases (16.08%), Helicobacter pylori infection in 16 cases (16.08%), chronic atrophic gastritis in 12 cases (13.46%), gastric polyps in 12 cases (13.46%), dysplasia in 10 cases (11.23%), benign ulcerations in seven cases (3.04%), edema in six cases (6.74%) and neoplasia two cases (2.24%).	16688361
Inflammation, Dysplasia, Infection caused by Helicobacter pylori, Edema, Polyposis, Gastric, Bile-induced gastritis	Altered Intercellular Communication	Acute inflammation, Helicobacter pylori infection, gastric polyps and benign ulcerations were more frequent in patients with bile reflux gastritis after gastric surgery, while edema and dysplasia were increased after biliary surgery.	16688361
Inflammation, Hyperlipidemia, Fibrosis Assessment, Diabetes Mellitus, Hepatobiliary Disorder, Obesity, Liver Cirrhosis, Fatty infiltration	Altered Intercellular Communication	It includes a broad spectrum of liver disease, from fatty infiltration, inflammation and fibrosis, to cirrhosis, usually having obesity, hyperlipidemia, and diabetes mellitus as its etiology.	16689200
Inflammation, Blood coagulation, Non-Vascular Plant, Thrombus, atherosclerotic	Altered Intercellular Communication	The exponential increases in risk of arterial and venous thrombotic events in men between age 60 and 79 years (when most such events occur) may be related in part to increasing activation of blood coagulation, fibrinolysis, and inflammation; possibly related to the increasing inflammatory burden of both atherosclerotic and non-vascular disease.	16689748
Inflammation, Heart failure, Thrombophilia	Altered Intercellular Communication	Markers of hypercoagulability and inflammation predict mortality in patients with heart failure.	16689753
Inflammation, Thrombophilia	Altered Intercellular Communication	Inflammation is strictly correlated with clotting activation, but the association between inflammation, hypercoagulability and prognosis in HF has not been previously reported.	16689753
Inflammation, Thrombophilia	Altered Intercellular Communication	Hypercoagulability and inflammation, as assessed by DD, TAT and IL-6 levels, are associated with an increased mortality risk in HF.	16689753
Inflammation, hepato-renal	Altered Intercellular Communication	Morphological analysis by light and electron microscopy showed degenerative processes in liver and kidney characterized by increased vascular permeability, chronic progressive inflammation, hemosiderin deposition, and general vasodilatation.	16690772
Infarction, Lacunar, Inflammation	Altered Intercellular Communication	High blood pressure and inflammation are associated with poor prognosis in lacunar infarctions.	16691020
Inflammation, Ototoxicity	Altered Intercellular Communication	When the logistic model was further adjusted for biomarkers of inflammation and excitotoxicity, IL-6 levels (OR 1.09, CI 95% 1.01-1.26, p = 0.003), but not SBP, was independently associated with poor outcome.	16691020
Communicable Diseases, Inflammation, Atherosclerosis	Altered Intercellular Communication	The infection of U937 cells with HCMV and especially C. pneumoniae induced inflammation and atherosclerosis-related genes.	16696549
Inflammation, Comorbidity	Altered Intercellular Communication	The association between the fourth cystatin C quartile and functional limitation remained after adjustment for demographics, lean body mass, comorbidity, muscle strength, and gait speed (HR=1.41, 95% CI=1.13-1.75), although the association was attenuated after adjustment for markers of inflammation (HR=1.15, 95% CI=0.90-1.46).	16696739
Inflammation, Obesity	Altered Intercellular Communication	Recently, it was shown that fat tissue produces and releases inflammatory cytokines, and that obesity may be regarded as a state of low-grade inflammation.	16696775
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Relationship between steatosis, inflammation, and fibrosis in chronic hepatitis C: a meta-analysis of individual patient data.	16697727
Hepatic inflammation, Fibrosis Assessment, Fatty degeneration, Diabetes Mellitus, Alcohol abuse	Altered Intercellular Communication	By stepwise logistic regression, steatosis was associated independently with genotype 3, the presence of fibrosis, diabetes, hepatic inflammation, ongoing alcohol abuse, higher body mass index, and older age.	16697727
Fibrosis Assessment, Hepatic inflammation, Fatty degeneration	Altered Intercellular Communication	In the subgroup analyses, the association between steatosis and fibrosis invariably was dependent on a simultaneous association between steatosis and hepatic inflammation.	16697727
Steatohepatitis, Hepatic inflammation	Altered Intercellular Communication	Hepatic inflammation may mediate fibrogenesis in patients with liver steatosis.	16697727
Inflammation, Primary Biliary Cholangitis, Intrahepatic bile duct	Altered Intercellular Communication	Intrahepatic bile ducts are the targets for inflammation in primary biliary cirrhosis (PBC), but their pathogenesis is not known.	16698669
Inflammation, Retinitis Pigmentosa, polychondritis	Altered Intercellular Communication	Relapsing polychondritis (RP) is characterized by inflammation and subsequent degeneration of cartilage.	16698708
Inflammation, Structure of suprasellar region, Infundibulo neurohypophysitis	Altered Intercellular Communication	Magnetic resonance imaging (MRI) data suggested the existence of lymphocytic infundibulohypophysitis, with inflammation of the suprasellar area.	16699303
Inflammation, Granuloma, Neoplasms, Traumatic injury, Hypopituitarism	Altered Intercellular Communication	Hypopituitarism can be caused by tumor, inflammation, granuloma and injuries.	16699306
Inflammation, Leukemia, Myelocytic, Acute	Altered Intercellular Communication	Histologically, the lesions were each composed of three components: 1) epithelial cysts lined by cuboidal to hobnail cells; 2) a compact subepithelial "cambium-like" layer of cellular, mullerian-like AML stroma with prominent admixed chronic inflammation; and 3) muscle-predominant AML with associated dysmorphic blood vessels exterior to the cellular subepithelial stroma.	16699313
Inflammation, Hemorrhage, Ischemia, Corneal stromal edema, Cytopathogenic Effect, Viral, Foveolar hyperplasia	Altered Intercellular Communication	Histologic changes included inflammation (100%), stromal edema (97.0%), foveolar hyperplasia (78.8%), ectatic vessels (66.7%), epithelial atypia (60.6%), increased glandular mitoses (57.6%), epithelial anisonucleosis (54.5%), fibrinopurulent materials (51.5%), ischemia (48.5%), stromal hemorrhage (33.3%), mucin depletion (12.1%), clear cell degeneration (15.2%), and signet-ring cell-like change (6.1%).	16699321
Inflammation	Altered Intercellular Communication	Coronary stenting is associated with acute inflammation within the arterial wall followed by neointimal growth.	16699978
Inflammation, Fulminant Hepatitis	Altered Intercellular Communication	In conclusion, transplantation of normal hepatocytes prevented fulminant hepatitis, reduces chronic inflammation, and improved 6-month survival in LEC rats.	16700326
Refractory anemias, Inflammation, Autoradiographic Image, Rheumatoid Factor	Altered Intercellular Communication	TNF-alpha role in RA is confirmed by the improvement on joint inflammation and physical function and by the slowing of radiographic damage induced by TNF-alpha blockers, that also reduce Rheumatoid Factor (RF) and anti-CC-P titres.	16700418
Inflammation, Thrombophilia, Gout, Autonomic nervous system disorders, Cerebrovascular accident, Acute Coronary Syndrome, Sleep Apnea, CTCAE, Sleep Disorders, Depression, CTCAE, Intestinal Diseases, Erectile dysfunction, Peripheral Vascular Diseases, Kidney Failure, Cardiac Arrhythmia	Altered Intercellular Communication	Restoration of normal flow in peripheral arterial disease may not only produce local benefit due to improved perfusion, but also represent a gateway to correcting many systemic conditions that may at first glance appear unrelated but share a common etiology of autonomic dysfunction, such as gout, acute coronary syndromes, stroke, sleep apnea, arrhythmias, depression, erectile dysfunction, inflammation, hypercoagulability, sleep disorders, bowel dysfunction, renal failure, and aging.	16701960
Inflammation, Data types - Address	Altered Intercellular Communication	Data obtained are indicative of the presence of an unregulated systemic inflammation in AD patients.	16702786
Gingivitis, Inflammation, Calculi, Dental Plaque	Altered Intercellular Communication	Although overall a higher proportion of children in this survey appeared to have gingival inflammation, plaque and calculus than 10 and 20 years ago, there was no change in the proportion of older children with gingivitis.	16703081
Necrotizing granulomatous inflammation, Granulomatosis with polyangiitis, Vasculitis, CTCAE, MULTISYSTEM DISORDER	Altered Intercellular Communication	Wegener's granulomatosis is a multisystem disorder characterized by necrotizing granulomatous inflammation and vasculitis of small vessels and can affect any organ system.	16703257
Abscess, Inflammation	Altered Intercellular Communication	The abscesses and inflammation resolved in all patients.	16703904
palladium, Inflammation	Altered Intercellular Communication	We assessed the gingival health of all subjects using the gingival inflammation (M-PMA) index and periodontal probing depth (PD).	16703929
Skin-associated lymphoid tissue lymphoma, Inflammation, "Sjogrens Syndrome", Neoplasms	Altered Intercellular Communication	Considering that salivary MALT lymphoma is associated with Sjogren's syndrome and that the chronic inflammation caused by Sjogren's syndrome persisted, it is hypothesized that the tumor clone might be present in the regressed lesion.	16704497
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Pathologically, the strand consisted of granulomatous inflammation with a wide zone of necrosis containing a dead ghost feature of a parasite in its center.	16704500
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Histopathology of the lesions revealed chronic granulomatous inflammation with numerous nonpigmented fungal spores in the dermis.	16704653
methyldopa, Inflammation, Atherosclerosis	Altered Intercellular Communication	A growing body of evidence suggests that inflammation contributes to the pathogenesis of AMD, similarly to that shown for atherosclerosis.	16704694
Inflammatory abnormality of the eye, Pterygium Of Conjunctiva And Cornea	Altered Intercellular Communication	All patients demonstrated early resolution of ocular inflammation and there was no recurrence of pterygium in any of the treated patients during the mean follow-up of 13.9 +/- 6.0 months.	16704707
Inflammation, Coronary heart disease	Altered Intercellular Communication	[Measurement peripheral blood index related to inflammation and ox-LDL, ox-LDLAb in patients with coronary heart disease and its clinical significance].	16706128
Inflammation, Acute Coronary Syndrome, Coronary heart disease, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	To detect the levels of index related to inflammation such as soluble CD40 ligand (sCD40L), neutrophil collagenase-8 (MMP-8), and pregnancy associated plasma protein-A (PAPP-A) , lipid peroxidation and autoimmune indexes such as oxidized low density lipoprotein (ox-LDL) and its antibody (ox-LDL Ab) in patients with coronary heart disease, and to investigate its relationship with acute coronary syndrome (ACS).	16706128
Inflammation, Rosacea	Altered Intercellular Communication	Metronidazole and azelaic acid are thought to reduce the inflammation associated with rosacea by inhibiting the production of reactive oxygen species produced by neutrophils.	16706244
Pain Distress Question, Inflammation, Crystal Arthropathies	Altered Intercellular Communication	Photobiomodulation of pain and inflammation in microcrystalline arthropathies: experimental and clinical results.	16706692
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	We investigated inflammation markers in young post-myocardial infarction patients exhibiting various expressions of classical risk factors.	16707954
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	We did not find differences in inflammation markers between young post-myocardial infarction patients with or without classical risk factors.	16707954
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Thus, it seems that the presence of (treated) risk factors or their absence does not affect the levels of inflammation markers in the stable period after myocardial infarction.	16707954
vascular inflammations	Altered Intercellular Communication	Importantly, we found similarly elevated interleukin-6 in both groups of patients, most probably indicating slight local vascular inflammation.	16707954
vascular inflammations, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Interleukin-6 appears to be the most suitable marker of vascular inflammation in post-myocardial infarction patients who are aggressively treated pharmacologically.	16707954
Inflammatory Bowel Diseases, Acute and chronic inflammation	Altered Intercellular Communication	The polymorphism may influence disease activity as well as more intense inflammatory activity in both forms of IBD and may modify the progression of chronic digestive tract inflammation.	16707968
Inflammation	Altered Intercellular Communication	DN patient has enhanced protein oxidation than DM patient, which is related to oxidative stress and chronic inflammation in DN.	16708815
Inflammation, Kidney Failure	Altered Intercellular Communication	Bowel inflammation may enhance absorption of oral vancomycin, particularly in those with renal failure.	16711316
Inflammation, Myocardial	Altered Intercellular Communication	The value of biomarkers of myocardial damage or inflammation in off-pump coronary artery bypass (OPCAB) surgery has not yet been established.	16712754
Inflammation	Altered Intercellular Communication	No significant differences were found with biomarkers of inflammation (P.05).	16712754
Urinary tract obstruction, Granulomatous inflammation, Communicable Diseases, Tuberculosis	Altered Intercellular Communication	Urinary obstruction is rarely associated with a distinct granulomatous inflammation, which involves the pyelocalyceal system and closely simulates infectious conditions including tuberculosis.	16715072
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Each case showed severe granulomatous inflammation, which was limited to the pelvic wall and closely associated with calcified debris, necrotic inflammatory cells, and material consistent with Tamm-Horsfall protein.	16715072
Necrotizing granulomatous inflammation, Urinary tract obstruction, Pyelitis	Altered Intercellular Communication	Granulomatous pyelitis is a rare but distinct cliniocopathologic entity characterized by severe noninfectious granulomatous inflammation limited to the renal pelvis, which is uniformely asociated with urinary obstruction and pyelocalyceal dilatation and may develop in response to accumulated calcified material in the renal pelvis.	16715072
Refractory anemias, Inflammation	Altered Intercellular Communication	Our results highlight free radical protein damage in RA and a link with inflammation, as underlined by the beneficial effects of infliximab.	16716286
Myelitis, N-nitrosomorpholine	Altered Intercellular Communication	However, some patients with otherwise typical NMO have additional symptoms not attributable to optic nerve or spinal cord inflammation or have MS-like brain MRI lesions.	16717206
Atherosclerosis	Altered Intercellular Communication	Inflammation contributes to the development of atherosclerosis and cardiovascular events.	16718633
Inflammation, Acute myocardial infarction, Atherosclerosis	Altered Intercellular Communication	Counteracting pro- and anti-inflammatory responses of serum cytokines have been reported, but the relevance of TNF-alpha, TGF-beta and IL-6 gene expression in peripheral blood leukocytes and their contribution to systemic inflammation in atherosclerosis, especially after acute myocardial infarction (AMI), has not been investigated yet.	16718633
Inflammation	Altered Intercellular Communication	Interestingly, we found no statistically significant correlation between transcript and protein levels, indicating that gene expression in leukocytes may be an independent sign for systemic inflammation.	16718633
Inflammation, Meningoencephalitis	Altered Intercellular Communication	This finding has been reported primarily in the acute inflammatory/demyelinating conditions, not in the viral meningitis/meningoencephalitis, and was thought to be related to cytokines due to widespread inflammation in our case.	16719407
Inflammation	Altered Intercellular Communication	Degeneration of the rotator cuff is often associated with inflammation of the subacromial bursa and focal mineralization of the supraspinatus tendon.	16719933
Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	In patients with idiopathic pulmonary fibrosis, Factor VIII levels and C-reactive protein levels were also elevated, supporting the presence of endothelial cell injury and inflammation.	16720208
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Autoimmune inflammation was suspected, and the patient received immunosuppressive therapy with immunoglobulins, steroids and azathioprine.	16720222
Single organ dysfunction, Inflammation, Coronary Arteriosclerosis, Cessation of life	Altered Intercellular Communication	Cerebral and myocardial ischemia, two of the leading causes of morbidity and mortality worldwide, are associated with inflammation that can lead to multiple organ failure and death.	16721263
Sepsis, Inflammation, Chemical injury, Shock, Hemorrhagic	Altered Intercellular Communication	High-mobility group box 1(HMGB1), a recently described mediator of lethal systemic inflammation, has been detected in individuals with severe sepsis and hemorrhagic shock, but its role during ischemic injury in humans is unknown.	16721263
allergic inflammation	Altered Intercellular Communication	IL-18 plays an important role in the pathogenesis of allergic inflammation and the SIT therapy.	16722393
Inflammation, Disorder of vein, Communicable Diseases, Ulcer, Rheumatoid Arthritis, Pyoderma Gangrenosum, Vasculitis, CTCAE	Altered Intercellular Communication	Patients with rheumatoid arthritis may develop leg ulcers of varied aetiologies, including venous disease, infection and inflammation (vasculitis or pyoderma gangrenosum).	16722900
Communicable Diseases, Inflammation, Ulcer	Altered Intercellular Communication	A new oxidised regenerated cellulose and collagen dressing has been developed for slow-to-heal wounds and may have a role in the management of superficial inflammation that may persist in many of these ulcers, although clinically it is difficult to distinguish this from critical colonisation or frank infection.	16722900
Inflammation, Ischemic stroke	Altered Intercellular Communication	Although many failed surrogate markers are provided in the literature, inflammation may contribute to the outcome of ischemic stroke.	16722977
Inflammation, Candida (fungus)	Altered Intercellular Communication	Diagnosis was made by histological identification of candida associated with inflammation from biopsy material taken during endoscopy.	16722997
Inflammation, Hemorrhage, diabetic	Altered Intercellular Communication	Women who met the inclusion criteria (being over 18 years old, having at least 18 teeth, not being diabetic, and having had children who survived labor) underwent a dental exam to look for hemorrhage when teeth were probed, loose teeth, or inflammation of the gums, and any loss of insertion was measured clinically.	16723066
Inflammation, Atherosclerosis	Altered Intercellular Communication	Retinal vascular caliber, cardiovascular risk factors, and inflammation: the multi-ethnic study of atherosclerosis (MESA).	16723443
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Chronic inflammation leading to malignancy in the esophagus may be due to errors in mismatch repair (MMR) genes such as hMLH1.	16724696
Coinfection, Inflammation, Atheroma	Altered Intercellular Communication	Co-infection ratios versus inflammation, growth factors and progression of early atheromas.	16725009
Inflammation	Altered Intercellular Communication	Mycoplasma can downregulate the immune system, altering levels of inflammation, which may favor the proliferation of other co-infectious agents.	16725009
Inflammation, Hyperplastic Polyp, Atheroma, Dental Plaque	Altered Intercellular Communication	MP and CP antigens are already present in early atheromas, and a higher MP/CP ratio correlates with increased growth factors, lower inflammation and plaque stability.	16725009
Helicobacter pylori, Stomach Carcinoma, Infection caused by Helicobacter pylori, Stomatitis, Atrophic	Altered Intercellular Communication	Response of IgG1 and IgG2 subclasses to Helicobacter pylori in subjects with chronic inflammation of the gastric mucosa, atrophy and gastric cancer in a country with high Helicobacter pylori infection prevalence.	16725014
Adenocarcinoma, Inflammation, Helicobacter pylori, Gastritis, Atrophic	Altered Intercellular Communication	Polarized immune response to Helicobacter pylori and induction of chronic inflammation may increase the risk of gastric atrophy and adenocarcinoma.	16725014
Stomach Carcinoma, Gastritis, Atrophic	Altered Intercellular Communication	We studied the association of the response of IgG1 and IgG2 antibodies to H. pylori with grade of gastric chronic inflammation and atrophy in a population with a high prevalence of H. pylori, and compared these data with the data obtained from the study of gastric cancer patients, as well as with the data for CagA positivity.	16725014
Inflammation, Gastritis, Gastritis, Atrophic	Altered Intercellular Communication	Helicobacter pylori IgG level was lower in atrophic gastritis compared with nonatrophic gastritis (chronic inflammation) (p=0.001).	16725014
Inflammation, Granulomatous Endometritis	Altered Intercellular Communication	Xanthogranulomatous inflammation is rare, mainly involving the kidneys, while primary xanthogranulomatous endometritis (XE) is a very unusual finding, histologically characterized by partial or complete replacement of the mucosa by granulation tissue with an abundance of foamy histiocytes, siderophages and multinucleated giant cells.	16725016
Inflammation, Heart failure	Altered Intercellular Communication	Despite antibiotic treatment the patient died of heart failure due to systemic inflammation.	16725016
vascular inflammations	Altered Intercellular Communication	These results highlight the need for aggressive risk factor modification and a decrease in vascular inflammation in obese patients.	16728212
Inflammation, destruction joint, Arthritis, Psoriatic	Altered Intercellular Communication	Detailed analysis of the cell infiltrate and the expression of mediators of synovial inflammation and joint destruction in the synovium of patients with psoriatic arthritis: implications for treatment.	16728461
PROS1 gene, Inflammation, destruction joint, Rheumatoid Arthritis	Altered Intercellular Communication	To investigate extensively the features of cell infiltration and expression of mediators of inflammation and joint destruction in the synovium of patients with PsA compared with patients with rheumatoid arthritis matched for disease duration and use of drugs.	16728461
Inflammation, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis begins in childhood, and inflammation may contribute to its pathophysiology.	16728658
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	The relation with the extent of coronary artery disease, the clinical syndrome and with a marker of inflammation will be documented.	16728874
Arthralgia, Inflammation	Altered Intercellular Communication	Infliximab therapy was initiated after 3 months because of persistent joint pain and inflammation.	16729012
Peripheral Vascular Diseases, Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	The role of coagulation and inflammation after angioplasty in patients with peripheral arterial disease.	16729229
Inflammation	Altered Intercellular Communication	Inflammation plays a critical role in the vascular response to injury.	16729229
Inflammation, Asthma	Altered Intercellular Communication	The central role of chronic inflammation of the airways in asthma pathogenesis is supported by the efficacy of corticosteroids in controlling clinical symptoms.	16729780
Inflammation, Spondylitis	Altered Intercellular Communication	Serum tissue factor levels correlate with inflammation in ankylosing spondylitis.	16730212
Inflammation	Altered Intercellular Communication	Tissue factor elevation may be a cause or a consequence of AS inflammation that promotes the occurrence of vascular events.	16730212
Heart Diseases, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cerebrovascular accident	Altered Intercellular Communication	Coexistence of insulin resistance and inflammation effectively predicts cardiac disease but not stroke in Japanese patients with type 2 diabetes mellitus.	16730841
Inflammation, macroangiopathy	Altered Intercellular Communication	It is well known that insulin resistance (IR) and inflammation (IF) are associated with macroangiopathy.	16730841
ovarian neoplasm, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Final pathology report revealed extensive non-caseating granulomatous inflammation within the ovarian tumor.	16731419
Inflammation, Bronchial Hyperreactivity, Chest tightness, Chronic Obstructive Airway Disease, Wheezing, Dyspnea	Altered Intercellular Communication	Asthma is a chronic disease of the airways in which inflammation causes bronchial hyper-reactivity and attacks of wheezing, dyspnea and chest tightness that are triggered by various agents.	16732710
Inflammation, Damage, MS gene	Altered Intercellular Communication	The pathological hallmarks of secondary progressive (SP) multiple sclerosis (MS) include slowly expanding demyelination and axonal damage with less inflammation.	16733654
Inflammation, Chronic sinusitis	Altered Intercellular Communication	Induction of CXC chemokines in A549 airway epithelial cells by trypsin and staphylococcal proteases - a possible route for neutrophilic inflammation in chronic rhinosinusitis.	16734624
Inflammation, Chronic sinusitis	Altered Intercellular Communication	Staphylococcal serine proteases induced CXC chemokines in A549 cells, probably by the activation of proteases activated receptors, and thus might potentially be involved in neutrophilic inflammation in chronic sinusitis.	16734624
Inflammation, Anemia, Hypoxemia, Disseminated Intravascular Coagulation	Altered Intercellular Communication	A 57-year-old man presented with severe anemia, inflammation, hypoxemia and disseminated intravascular coagulation.	16734873
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Cigarette smoking, lipids, and inflammation contribute to LV-PAD progression, whereas diabetes was the only significant predictor of SV-PAD progression.	16735675
Refractory anemias, Inflammation	Altered Intercellular Communication	The application of multi-site QUS seems to be restricted for patients with active inflammation based on soft tissue alteration in RA and for healthy individuals with pronounced body mass.	16736163
Communicable Diseases, Amoeba genus, Inflammation, Acute appendicitis NOS (disorder)	Altered Intercellular Communication	Comparing the cases in this study against the cases of patients with acute appendicitis in general (excluding the cases of amebic origin), no differences were found in relation to the distribution or presentation according to sex or in the degree of inflammation of the appendix, the incidence of surgical wound infection, or general complications.	16736334
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	In the other nine patients inflammation of the anastomosis was seen in seven with Crohn's disease (CD) and two with ulcerative colitis.	16736477
Inflammation, Arthritis	Altered Intercellular Communication	These findings represent a possible mechanism for perpetuation of joint inflammation in the subgroup of arthritis patients with high levels of anti-CII.	16736518
Hip Joint, Inflammation, Spondylitis	Altered Intercellular Communication	Previous histopathologic and magnetic resonance imaging studies suggest that the subchondral bone marrow might be the primary site of inflammation in patients with ankylosing spondylitis (AS) and that this might be reflected by inflammation found in hip joints.	16736521
Inflammation	Altered Intercellular Communication	These findings suggest that the subchondral bone marrow and bone-cartilage interface are primary sites of inflammation in AS and that cartilage might be necessary for the induction of inflammation.	16736521
Inflammation, Cerebrovascular accident, Acute Coronary Syndrome, Thrombus, Embolism	Altered Intercellular Communication	The assembled findings of elevated inflammatory parameters in patients with CVA of a thrombotic etiology as compared with patients with CVA with embolic etiology indicate similarly as in patients with acute coronary syndrome - the possible role of inflammation in the etiopathogenesis of thrombotic CVA.	16737144
Inflammation, Thromboembolism of vein	Altered Intercellular Communication	[Acute-phase reactants and markers of inflammation in venous thromboembolic disease: correlation with clinical and evolution parameters].	16737429
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP) is emerging as an important predictor of cardiovascular disease (CVD), and chronic inflammation may be a mechanism through which stress affects disease risk.	16738067
Inflammation	Altered Intercellular Communication	Psychosocial stress, as well as health behaviors, are important predictors of inflammatory activity in a population-based sample and should be considered in future research on inflammation and CVD.	16738067
Inflammation, Comorbidity	Altered Intercellular Communication	We examined longitudinal changes in bone mineral parameters and whether their associations with mortality were independent of time on dialysis, inflammation, and comorbidity.	16738536
Inflammation, Comorbidity	Altered Intercellular Communication	In Cox proportional hazards models adjusting for inflammation, comorbidity, and other confounders, the highest quartile of phosphate was associated with a hazard ratio (HR) of 1.57 (1.07-2.30) using both baseline and time-dependent values.	16738536
Inflammation, Hyperplasia	Altered Intercellular Communication	A histological inflammation score was determined based on the hyperplasia of the synovial lining and infiltration of inflammatory cells.	16738904
Inflammation	Altered Intercellular Communication	The IL-6 level in synovial fluid partially reflects histological synovial inflammation.	16738904
Airway structure, Inflammation	Altered Intercellular Communication	Patterns of inflammation and the use of reversibility testing in smokers with airway complaints.	16740168
ARCN1 gene, Inflammation	Altered Intercellular Communication	COPD and so-called healthy smokers showed consistent opposite associations with plasma LBP, while chronic bronchitics showed relatively predominant lymphocytic inflammation compared to other diagnosis groups.	16740168
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Skeletal muscle structure	Altered Intercellular Communication	Altered muscle amino acid metabolism resulting in skeletal muscle dysfunction is one of the systemic effects of chronic obstructive pulmonary disease (COPD) associated with systemic oxidative stress and inflammation.	16740433
Inflammation, Uveitis	Altered Intercellular Communication	When inflammation in uveitic eyes is under complete control, phacoemulsification and implantation of a foldable acrylic IOL in the posterior chamber is safe, effective, and tolerated well.	16749256
Inflammation, Anterior scleritis	Altered Intercellular Communication	Anterior scleritis is defined as an inflammation of the sclera, located anteriorly to the equator of the eye.	16750283
Inflammation, Lipoprotein (a) measurement, atherosclerotic	Altered Intercellular Communication	Pregnancy-associated plasma protein-a is markedly expressed by monocyte-macrophage cells in vulnerable and ruptured carotid atherosclerotic plaques: a link between inflammation and cerebrovascular events.	16750685
Cessation of life, Inflammation	Altered Intercellular Communication	IRP and low-grade inflammation predicted 57% of observed deaths and 97% of survival over 2 years, and was not significantly affected by individuals' health status, suggesting that the physiological ageing processes of T-cell immunosenescence and low-grade inflammation are of primary importance in late life survival.	16750842
Inflammation, Atherosclerosis	Altered Intercellular Communication	We set out to estimate the incremental prognostic utility of inflammation and atherosclerosis markers in the prediction of all-cause and CV mortality in elderly men.	16750966
Allergic asthma, Inflammation, Asthma	Altered Intercellular Communication	These findings support the critical role of IgE in the regulation of inflammation in allergic asthma: influencing the inflammation is the key to control the more severe type of asthma.	16751018
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Inflammation is implicated in the development of type 2 diabetes and CHD, but the trigger of inflammation is unclear.	16752182
Inflammation, Demyelination, Subacute Sclerosing Panencephalitis	Altered Intercellular Communication	The MRS findings suggested active inflammation and demyelination as is seen in early-stage SSPE.	16752349
Inflammation	Altered Intercellular Communication	AVG and TPC have a higher degree of chronic inflammation than AVF.	16755161
Immobile	Altered Intercellular Communication	Inflammation of the arytenoid region and vocal cord immobility were observed by fiberoptic nasolaryngoscopy.	16755245
vascular inflammations, Cytomegalovirus, Atherosclerosis	Altered Intercellular Communication	Logistic regression was used to test the correlation between the presence of CMV, vascular inflammation, and traditional noninflammatory risk factors for atherosclerosis.	16755441
Inflammation, Obstruction	Altered Intercellular Communication	The study demonstrates a significant role of ACE activity changes in the progression of obstruction, inflammation, and myocardial remodeling.	16755852
Airway structure, Pomalidomide-Cyclophosphamide-Dexamethasone Regimen	Altered Intercellular Communication	We hypothesize that calcite stone formation is a biomineralization response to chronic airway inflammation and retention of infected airway secretions in PCD in a subset of PCD patients.	16757159
Inflammation, AUTONOMIC NERVOUS SYSTEM DYSFUNCTION	Altered Intercellular Communication	Pathways by which particles may act involve autonomic nervous system dysfunction or inflammation, which can affect cardiac rate and rhythm.	16757505
Inflammation, Hemorrhage	Altered Intercellular Communication	Endometria of LTPOC-treated patients display aberrant angiogenesis with abnormally enlarged, thin-walled, fragile blood vessels, inflammation, and focal hemorrhage.	16757524
Parkinson Disease, palladium	Altered Intercellular Communication	Imaging the dopaminergic neurotransmitter system with positron emission tomography (PET) or single photon emission tomography (SPECT) is a powerful tool for the diagnosis of Parkinson's disease (PD).	16757862
Coughing, Inflammation, Nasal allergies	Altered Intercellular Communication	Eosinophilic inflammation, remodeling of lower airway, bronchial responsiveness and cough reflex sensitivity in non-asthmatic subjects with nasal allergy.	16757921
Airway structure, Nasal allergies	Altered Intercellular Communication	It has been reported that nasal allergy influences the lower airway inflammation and functions.	16757921
Airway structure, Nasal allergies	Altered Intercellular Communication	We elucidated whether nasal allergy would contribute to lower airway inflammation and functions.	16757921
Inflammation, Bronchial Hyperreactivity	Altered Intercellular Communication	These results suggest that eosinophilic inflammation occurred in symptomatic period of PAR may contribute to development of lower airway remodeling and bronchial hyperresponsiveness.	16757921
Eosinophilic inflammation	Altered Intercellular Communication	Reversely, PO may not be associated with lower airway eosinophilic inflammation or abnormal bronchial functions.	16757921
Inflammation, Interstitial inflammation	Altered Intercellular Communication	Focal mild inflammation was shown in 46 of the 104 specimens (32.9%), including interstitial inflammation in 42 specimens, inflammation in both interstitial and body of gland in 3 specimens, and perigladulitis in 1 specimen.	16759539
Inflammation, Papilledema	Altered Intercellular Communication	Bilateral disc edema was thought to be secondary to inflammation caused by rapid degeneration of photoreceptors and retinal pigment epithelium and macular hole was secondary to CME.	16761258
Orbital Pseudotumor	Altered Intercellular Communication	Biopsy yielded a diagnosis of sclerosing idiopathic orbital inflammation.	16761644
Xanthogranulomatous inflammation	Altered Intercellular Communication	The pathogens generally found to cause xanthogranulomatous inflammation have been Proteus and E. coli.	16762415
Inflammation, Ventricular Dysfunction, Left	Altered Intercellular Communication	Temporal increases in subclinical levels of inflammation are associated with adverse clinical outcomes in patients with left ventricular dysfunction.	16762798
Inflammation, Weight decreased, Cachexia	Altered Intercellular Communication	Definition of cancer cachexia: effect of weight loss, reduced food intake, and systemic inflammation on functional status and prognosis.	16762946
Inflammation, Weight decreased, Cachexia	Altered Intercellular Communication	Our objective was to evaluate whether a 3-factor profile incorporating weight loss (> or = 10%), low food intake (< or = 1500 kcal/d), and systemic inflammation (C-reactive protein > or = 10 mg/L) might relate better to the adverse functional aspects of cachexia and to a patient's overall prognosis than will weight loss alone.	16762946
Inflammation, Weight decreased	Altered Intercellular Communication	The 3-factor profile (weight loss, reduced food intake, and systemic inflammation) identifies patients with both adverse function and prognosis.	16762946
Inflammation, Atherosclerosis	Altered Intercellular Communication	Dietary patterns are associated with biochemical markers of inflammation and endothelial activation in the Multi-Ethnic Study of Atherosclerosis (MESA).	16762949
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Dietary patterns may influence cardiovascular disease risk through effects on inflammation and endothelial activation.	16762949
Mucocutaneous Lymph Node Syndrome, Kimura Disease	Altered Intercellular Communication	Kimura's disease (KD) is a rare, chronic inflammatory condition of unknown origin that is more commonly seen in Asia.	16763415
Inflammation, Sepsis-associated myocardial dysfunction	Altered Intercellular Communication	It remains to be determined how elevations of natriuretic peptide levels are linked to inflammation and sepsis-associated myocardial dysfunction.	16763507
Inflammation	Altered Intercellular Communication	These results suggest that suppressor cells migrate to and/or multiply at the sites of inflammation as part of the immune responses' effort to combat injurious inflammation.	16764698
Inflammation, Angina, Unstable	Altered Intercellular Communication	Heart rate variability (HRV) and systemic markers of inflammation have prognostic value in patients with unstable angina pectoris (UAP).	16765117
Inflammatory Bowel Diseases, Inflammatory abnormality of the eye	Altered Intercellular Communication	Family history of inflammatory bowel disease in patients with idiopathic ocular inflammation.	16765679
Inflammatory Bowel Diseases, Opportunistic Infections, Inflammatory abnormality of the eye	Altered Intercellular Communication	To determine the prevalence of a family history (FMH) of inflammatory bowel disease (IBD) in patients with idiopathic ocular inflammation (OI).	16765679
Inflammation, Uveomeningoencephalitic Syndrome	Altered Intercellular Communication	Association between severity of inflammation in CNS and development of sunset glow fundus in Vogt-Koyanagi-Harada disease.	16765691
Inflammation, Uveomeningoencephalitic Syndrome	Altered Intercellular Communication	To investigate the association between central nervous system (CNS) inflammation at disease onset and the appearance of sunset glow fundus (SGF) in Vogt-Koyanagi-Harada (VKH) disease.	16765691
Inflammation, neuron death	Altered Intercellular Communication	There are age-related differences in susceptibility of the immature brain to oxidative stress and inflammation, as well as in the rate and degree of apoptotic neuronal death.	16765824
Inflammatory abnormality of the eye	Altered Intercellular Communication	The relationship between etanercept administration and the patient's systemic and ocular inflammation was assessed.	16766397
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation is paradoxically a potential adverse event following the use of etanercept in both previously uninvolved and inflamed eyes.	16766397
Inflammatory abnormality of the eye, Exacerbation of cGVHD	Altered Intercellular Communication	Careful surveillance of patients on etanercept is warranted to assure that flares in ocular inflammation are not secondary to etanercept therapy.	16766397
Uveitis	Altered Intercellular Communication	To investigate the additional benefit of indocyanine green angiography (ICGA) over fundus fluorescein angiography (FA) in patients with posterior uveal inflammation.	16766401
Inflammatory abnormality of the eye	Altered Intercellular Communication	She was treated with topical steroids and mydriatics with resolution of ocular inflammation.	16766405
Weight decreased, Osteopenia	Altered Intercellular Communication	Lower levels of endogenous sex steroids or declines in these hormones may contribute to the increased rates of bone loss observed in older adults experiencing weight loss.	16767524
Dyspnea, Inflammation, Lymphadenopathy	Altered Intercellular Communication	The clinical signs consisted of worsening of the patient's general condition, negacervical lymphadenopathy, night sweats, dyspnea, and superficial inflammation of the right mamma.	16767573
Acute appendicitis NOS (disorder)	Altered Intercellular Communication	Criteria for diagnosis of acute appendicitis included an enlarged appendix (>6 mm diameter) and periappendiceal inflammation.	16767943
Pain Distress Question, Inflammation, Disease remission, Joint deformity	Altered Intercellular Communication	The permanent joint deformity was present in 33.3% patients and 36.9% patients were suffering from active disease with pain and inflammation.	16767957
Inflammation, Anxiety, CTCAE 3.0, Depression, CTCAE, Joint deformity	Altered Intercellular Communication	Educational qualification, permanent joint deformity, active inflammation and time elapsed since diagnosis had significant association with anxiety and depression.	16767957
Blindness, Orbital Pseudotumor	Altered Intercellular Communication	Early, appropriate evaluation and management observing signs and symptoms of orbital inflammation are required to prevent blindness.	16768160
Inflammation	Altered Intercellular Communication	We report the first case where a silastic sheet applied during a facial reconstruction had migrated adjacent to the lacrimal sac resulting in severe inflammation.	16768193
Choledochal Cyst, Inflammation, Mirizzi Syndrome, Cholelithiasis, Bile duct structure, Type 2	Altered Intercellular Communication	Mirizzi's syndrome is a rare complication of cholelithiasis, and type II (cholecystocholedochal fistula) can be a technical challenge due to inflammation and the biliary duct defect.	16769004
Autoimmune Diseases, Idiopathic Inflammatory Myopathies, Myositis	Altered Intercellular Communication	Idiopathic inflammatory myopathies (IIMs) are systemic autoimmune diseases characterized by chronic muscle inflammation resulting in progressive weakness and frequent involvement of internal organs, mainly the pulmonary, gastrointestinal and cardiac systems which considerably contribute to the morbidity and mortality of the IIMs.	16769656
ARCN1 gene, Airway structure, Pulmonary Emphysema, physiopathological, Impaired	Altered Intercellular Communication	These results suggest that COPD associated with HRCT confirmed emphysema is characterised by more severe lung function impairment, more intense airway inflammation and, possibly, more serious systemic dysfunction than COPD not associated with HRCT confirmed emphysema.	16769715
Uveal prolapse, Infectious Endophthalmitis, Uveitis	Altered Intercellular Communication	Other complications included pupillary capture in 2 (8.7%) eyes and uveal prolapse in 1 (4.3%) eye in the acrylic group and increased uveal inflammation in 6 (26.1%) eyes and presumed noninfectious endophthalmitis in 2 (8.7%) eyes in the PMMA group.	16770027
Polycystic Ovary Syndrome, Uveitis	Altered Intercellular Communication	Incidence of PCO and post operative uveal inflammation is significantly less with acrylic lenses and were safe to use in pediatric eyes.	16770027
Inflammation, Scleritis	Altered Intercellular Communication	Posterior scleritis should be suspected when evaluating subretinal mass-lesions, even when large and without overt inflammation.	16770031
Inflammation, Cachexia	Altered Intercellular Communication	In hemodialysis patients an inverse correlation between WBC count as a marker of inflammation with serum Hcy level as a marker of nutritional status, further support the hypothesis of the malnutrition-inflammation cachexia syndrome	16773964
Inflammation, Colorectal Neoplasms	Altered Intercellular Communication	Chronic inflammation has been reported to be a risk factor for colorectal neoplasia.	16775170
Polyp of large intestine, Adenoma of large intestine	Altered Intercellular Communication	We investigated the association of colorectal adenoma with 19 single nucleotide polymorphisms in a range of important proinflammatory (IL1B, IL6, IL8, TNF, and LTA) and anti-inflammatory (IL4, IL10, and IL13) cytokines and other inflammation-related genes (PTGS2 and PPARG) in a case-control study of risk factors for colorectal polyps in which all participants (ages 18-74 years) had undergone colonoscopy or sigmoidoscopy.	16775170
Inflammation, Adenoma of large intestine	Altered Intercellular Communication	These exploratory data provide evidence that polymorphic variation in genes that regulate inflammation could alter risk for colorectal adenoma.	16775170
Prostate, Neoplasms	Altered Intercellular Communication	Inflammation of the prostate has been suggested to favor tumor development.	16775185
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Factors determining the extension and degree of inflammation in the colonic mucosa of patients with ulcerative colitis (UC) are largely unknown, but CD4+CD25high regulatory T cells (Tregs) have been implicated to play an important role in suppressing inflammation.	16775488
Inflammation	Altered Intercellular Communication	Resistin, interleukin-6, and monocyte chemotactic protein-1 were not specifically induced in CD but were associated with unspecific inflammation.	16775490
Gastrointestinal inflammation	Altered Intercellular Communication	A specific secretion pattern of proinflammatory and anti-inflammatory adipocytokines indicates the significance of adipose tissue in intestinal inflammation in CD.	16775490
Inflammation, Shock, Cardiogenic	Altered Intercellular Communication	Inflammation may play an important role in the pathogenesis, persistence, and prognosis of cardiogenic shock.	16775569
Kidney Failure, Chronic, Inflammation, Cessation of life, Cardiovascular system	Altered Intercellular Communication	Since fT3 in patients with end-stage renal diseases (ESRD) is frequently reduced and is associated with inflammation and cardiovascular damage, we prospectively tested the hypothesis that it predicts death in a cohort of 200 hemodialysis patients.	16775599
Inflammation	Altered Intercellular Communication	These data suggest a central role for glomerular clusterin in MGN as a modulator of inflammation that potentially influences the clinical outcome.	16775601
Inflammation, Dryness (characteristic), Data types - Address, Erythema	Altered Intercellular Communication	AD is associated with a wide array of symptoms, including itching, dryness, erythema, crusted lesions, and superficial inflammation.	16776289
Inflammation, Lung Diseases, Obstructive, Impaired lung function	Altered Intercellular Communication	Increased levels of systemic markers of inflammation have been reported in patients with impaired lung function due to obstructive or restrictive lung disease.	16778162
Inflammation	Altered Intercellular Communication	We tested the hypothesis that a decline in lung function within the normal range may be associated with a systemic subclinical inflammation.	16778162
Inflammation	Altered Intercellular Communication	These results indicate that systemic inflammation may be linked to early perturbations of pulmonary function.	16778162
Inflammation, Sarcoidosis	Altered Intercellular Communication	Our results suggest that inflammation could be effectively and noninvasively determined by using sputum induction in sarcoidosis patients.	16778280
Airway structure, Symptoms, Gastroesophageal reflux disease	Altered Intercellular Communication	Aspiration of acid to the airway causes airway inflammation, and acid stress to the airway caused by gastroesophageal reflux disease (GERD) has been known as a potential mechanism of deteriorated asthma symptoms.	16778364
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Prospective studies have demonstrated that markers of inflammation, such as high-sensitivity C-reactive protein (hsCRP) and fibrinogen, predict future cardiovascular disease risk.	16778366
Airway structure, Asthma, Aspirin-Induced	Altered Intercellular Communication	Circulating autoantibodies in patients with aspirin-intolerant asthma: an epiphenomenon related to airway inflammation.	16778381
Pleurisy	Altered Intercellular Communication	Septal lines in pleural inflammation: multidetector computed tomography findings in 30 patients.	16778623
Pleurisy	Altered Intercellular Communication	The multidetector computed tomography scans of 30 patients with pleural inflammation were retrospectively and blindly evaluated by 2 observers.	16778623
Pleurisy	Altered Intercellular Communication	More than 10 septal lines immediately adjacent to the abnormal pleura were seen in 22 of the 30 patients with pleural inflammation and 2 of the 7 patients with fibrothorax (P<0.01).	16778623
Acute inflammation	Altered Intercellular Communication	Septal lines that are more than 1 mm thick were seen in 13 of the 30 patients with acute inflammation and none of the patients with fibrothorax (P<0.01).	16778623
Pleurisy	Altered Intercellular Communication	Differences between focal and diffuse pleural inflammation included 10 cm or greater craniocaudal extent and more smooth septal lines with diffuse pleural inflammation.	16778623
Pleurisy	Altered Intercellular Communication	Pleural inflammation is associated with increased number and thickening of septal lines in the immediately adjacent lung parenchyma.	16778623
Inflammation, Spinal Diseases	Altered Intercellular Communication	CSF HA concentration might be a secondary marker for inflammation in patients with spinal disease.	16778660
Inflammation, Pain Distress Question	Altered Intercellular Communication	However, the exact pathomechanism by which a degenerative intervertebral disk leads to neural inflammation and pain has not been determined.	16778661
Colorectal Carcinoma, Chronic inflammation, Irritable Bowel Syndrome	Altered Intercellular Communication	Subjects were a total of 240 persons, including 60 patients with irritable bowel syndrome, 60 patients with colorectal cancer, 60 patients with chronic inflammation, and 60 healthy controls.	16778979
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The median of fecal calprotectin concentrations were 159.00 mg/kg and 466.00 mg/kg in colorectal cancer and chronic inflammation respectively.	16778979
Colorectal Carcinoma, Chronic inflammation	Altered Intercellular Communication	There were statistical significance between patients with chronic inflammation, colorectal cancer, and others (P<0.01).	16778979
Inflammation, Ichthyosis Bullosa of Siemens, Colorectal Carcinoma	Altered Intercellular Communication	The maximal calprotctin concentration was with chronic inflammation; the medium with colorectal cancer; the minimum with IBS and healthy controls.	16778979
Inflammation, Ichthyosis Bullosa of Siemens, Colorectal Carcinoma	Altered Intercellular Communication	When the cut-off limit was set as 50 mg/kg of fecal calprotectin, the positive rates of colorectal cancer, chronic inflammation, IBS and healthy controls were 85.0%, 91.7%, 10%, and 5%,respectively.	16778979
Intraocular inflammation, Lens dislocation	Altered Intercellular Communication	This patient demonstrated that lens dislocation into the vitreous body can be present for a long time without causing any intraocular inflammation.	16779568
Rotator cuff syndrome, Inflammation	Altered Intercellular Communication	Several studies have demonstrated that inflammation in the subacromial bursa is an important component in the pathogenesis of impingement syndrome.	16779827
Communicable Diseases, Inflammation	Altered Intercellular Communication	As expected, lower airway anatomical abnormalities, infection, and inflammation were common.	16779841
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Analyses of fluids revealed that both were exudative and sterile, and pleural biopsy showed nonspecific inflammation with mild fibrosis.	16780097
Inflammation, Hyperkeratosis	Altered Intercellular Communication	Histologic examination showed follicular and interfollicular hyperkeratosis, follicular plugging, mild inflammation, and focal scarring.	16780474
Inflammation, Thrombosis, Atherosclerosis	Altered Intercellular Communication	Moreover, the IMAGINE population is not only a lower risk population than those enrolled in HOPE or EUROPA, but also the risk for this population is bimodal in nature (early post-revascularization inflammation and thrombosis vs long-term atherosclerosis progression) and may provide further insight into underlying mechanisms.	16781228
Inflammation, carotid disease, Plaque, Atherosclerotic	Altered Intercellular Communication	Increased activity of the ubiquitin-proteasome system in patients with symptomatic carotid disease is associated with enhanced inflammation and may destabilize the atherosclerotic plaque: effects of rosiglitazone treatment.	16781372
Inflammation, Disorder of tendon	Altered Intercellular Communication	Three hundred fifty-seven patients aged 18 to 93 years with tendinopathy of varying etiology based on excessive tendon load rather than inflammation.	16781589
Axonal degeneration, Inflammation	Altered Intercellular Communication	Neuropathology of the sural nerve showed an axonal degeneration and perivascular inflammation and electromyography revealed neurogenic changes.	16781792
vascular inflammations, Hypertension, CTCAE	Altered Intercellular Communication	C-reactive protein (CRP) has been known to be associated with vascular inflammation and hypertension.	16782104
Arterial Stiffness, Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Therefore, hsCRP could be a useful marker of arterial stiffness in treated hypertension patients and a possible target for arterial inflammation in hypertension.	16782104
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Whether citrullination significantly contributes to the initiation or perpetuation of autoimmunity or merely reflects ongoing inflammation remains to be clarified.	16782731
Inflammation, Heart valve disease	Altered Intercellular Communication	Inflammation may play a central role in the progression of stenotic valvular heart disease.	16784074
Inflammation, Mitral Valve Stenosis, Heart valve disease	Altered Intercellular Communication	Serum levels of MMP-9 were elevated in patients with mitral stenosis, providing further evidence that inflammation and ECM remodeling plays an important role in the pathophysiology of valvular heart disease.	16784074
Inflammation, Encephalomyelitis, Acute Disseminated	Altered Intercellular Communication	Our data suggest that the upregulation of chemokines active on neutrophils and Th2 cells differentiates ADEM from MS inflammation, and that both Th1 and Th2 chemokines might be produced in ADEM.	16784758
Inflammation	Altered Intercellular Communication	These findings support the hypothesis that inflammation contributes to the etiology of AF.	16784925
Inflammation, Fibrosis Assessment, Blood capillaries	Altered Intercellular Communication	On pathologic examination, there were varying degrees of both septal fibrosis and inflammation along with evidence of septal capillary injury.	16785792
Inflammation, Hepatitis C, Breast Carcinoma, Lymphadenopathy	Altered Intercellular Communication	The resolution of the lymphadenopathy and the patient's clinical course led to the conclusion that the most likely explanation for the FDG PET/CT findings was inflammation secondary to acute hepatitis C infection and not metastatic breast carcinoma.	16785802
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	In contrast, patients with elevated CRP levels were at higher risk of stroke or transient ischemic attack, reinforcing the link between inflammation and CVE.	16786236
Inflammation, Respiration Disorders	Altered Intercellular Communication	The evaluation of breath condensate (BC) composition is a new, non-invasive method studying inflammation processes in several respiratory diseases.	16786744
Inflammation, Fibrosis Assessment, Asthma	Altered Intercellular Communication	Among many inflammation markers, hydrogen peroxide (H2O2) is the most common one, and its increased level was found in BC of cystic fibrosis and asthma patients.	16786744
Airway structure, Allergic, Asthma, Common Cold	Altered Intercellular Communication	We conclude that hydrogen peroxide in exhaled breath condensate of children with stable mild asthma does not differ significantly in allergic and non-allergic children and activity of airway inflammation seems to independent on allergic status of patients.	16786744
Refractory anemias, Rheumatoid Arthritis, Inflammation, Osteoporosis	Altered Intercellular Communication	Osteoporosis associated with rheumatoid arthritis (RA) is induced by chronic inflammation.	16786754
Bone Density, UGCG gene, Inflammation	Altered Intercellular Communication	Short-term low dose GCS therapy dramatically reduce inflammation which temporarily may reduce the loss of bone mass.	16786754
methyldopa, Inflammation	Altered Intercellular Communication	This functional alteration may affect binding of factor H to polyanionic patterns on host surfaces, potentially influencing complement activation, immune complex clearance, and inflammation in the macula of AMD patients.	16787919
Inflammation, Fibrosis Assessment, Endothelial dysfunction	Altered Intercellular Communication	The observed contrast uptake may be associated with endothelial dysfunction, neovascularization, inflammation, and/or fibrosis.	16787955
Inflammation, Hypertrophic neuropathy	Altered Intercellular Communication	Sural-nerve biopsy specimens showed hypertrophic neuropathy with no superimposed inflammation.	16788010
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	The pathogenesis of Alzheimer's disease (AD) has been linked to a deficiency in the brain neurotransmitter acetylcholine.	16788077
Inflammation, Myocarditis, CTCAE 5.0, Myocardium	Altered Intercellular Communication	Myocarditis is inflammation of cardiac muscle, which may be acute, subacute, or chronic with either focal or diffuse involvement of the myocardium.	16788323
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Relationships of physical activity with metabolic syndrome features and low-grade inflammation in adolescents.	16791618
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Physical activity has beneficial effects on symptoms of the metabolic syndrome and low-grade inflammation in adults.	16791618
Intervertebral disc structure	Altered Intercellular Communication	The role of radioisotopic methods in imaging of intervertebral disc inflammation in children.	16791810
Inflammation	Altered Intercellular Communication	Anti-calsequestrin antibodies were detected in 78% of patients with active congestive ophthalmopathy, in 92% of those with active inflammation and eye muscle involvement, but in only 22% of patients with chronic, 'burnt out' disease.	16792674
Inflammation, Fibrosis Assessment, Systemic Scleroderma, Sample Size Calculation, Hypertrophy, Connective Tissue Diseases	Altered Intercellular Communication	Endothelin-1 is considered to be a central pathogenic factor in connective tissue diseases (CTDs) such as systemic sclerosis (SSc), leading to vasoconstriction, fibrosis, hypertrophy and inflammation.	16793845
Inflammation, Airway structure, Communicable Diseases, Transplanted tissue, Tracheobronchomalacia, Traumatic injury	Altered Intercellular Communication	Causes of airway stenosis included transplant stricture (n = 13), tracheal tube injury (n = 10), inflammation (n = 6), tracheobronchomalacia (n = 4), infection (n = 3), and extrinsic compression (n = 4).	16793984
Inflammation	Altered Intercellular Communication	These volunteers' acute inflammation had been inhibited by LKM512 yogurt consumption in a previous test.	16794305
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Deregulated expression of monocyte chemoattractant protein-1 (MCP-1) in arterial hypertension: role in endothelial inflammation and atheromasia.	16794480
Inflammation, Injury of gastrointestinal tract	Altered Intercellular Communication	Nitric oxide (NO) production is elevated in the intestine and may contribute to intestinal injury during inflammation.	16795973
Inflammation, Gastro-esophageal reflux disease with esophagitis	Altered Intercellular Communication	Since vascular endothelial growth factor (VEGF) exerts its action on microcirculation, contributing to angiogenesis and inflammation, we examined the role of VEGF together with iNOS and eNOS on development of reflux esophagitis.	16795973
Vasculitis of large artery, Takayasu Arteritis, Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Takayasu's arteritis (TA) is a nonspecific autoimmune inflammation manifested with systemic large vessel vasculitis which affects predominantly the aorta and its main branches.	16796030
Inflammation, Heart failure	Altered Intercellular Communication	CRP was chosen as a model analyte because of its widely accepted role as a marker for acute inflammation and prospective heart failure.	16796400
Inflammation, Irritable Bowel Syndrome	Altered Intercellular Communication	We recently showed that patients with post-infective irritable bowel syndrome have increased postprandial release of 5-HT associated with low-grade T-cell mediated inflammation.	16797248
ARCN1 gene, Inflammation	Altered Intercellular Communication	Interrelationships between biomarkers were examined to gain information on mechanisms of systemic inflammation at exacerbation of COPD.	16799074
Communicable Diseases, Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	The results support the hypothesis that a chronic latent Cp infection with inflammation might accelerate the development of early stage atherosclerotic lesions.	16799231
Inflammation, Damage, PPP1R13L gene	Altered Intercellular Communication	The Banff rejection activity index (RAI) comprises 3 components scored from 0 to 3: venous endothelial inflammation (E); bile duct damage (B); and portal inflammation (P); the scores are combined to an overall score (the RAI).	16799959
Neurogenic Inflammation, Pruritus	Altered Intercellular Communication	They could also be impairment of nervous conduction, as suggested by the absence of pruritus, with partial or total inhibition of neurogenic inflammation.	16800176
Inflammation, Infection	Altered Intercellular Communication	Getting ready for certification: urinary tract inflammations and infections.	16800328
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Both results were significantly elevated compared with those of healthy controls [114 (113)] mg/kg In patients with IBD, their levels correlated directly with the activity of the inflammation.	16801001
Hepatosplenomegaly, Inflammation, Infection, Hyperzincemia and Hypercalprotectinemia, Anemia, Arthritis, Failure (biologic function)	Altered Intercellular Communication	Hyperzincaemia and hypercalprotectinaemia with systemic inflammation, recurrent infections, hepatosplenomegaly, arthritis, anemia, cutaneous inflammation, and failure to thrive is an extremely rare disease and no therapy is reported.	16801185
Hepatosplenomegaly, Inflammation, Pyoderma Gangrenosum, Anemia, Arthritis	Altered Intercellular Communication	A 10-year-old girl was admitted suffering from pyoderma gangrenosum, hepatosplenomegaly, anemia that was unresponsive to iron supplementation, persistent inflammation, arthritis, and increased serum zinc.	16801185
Inflammation, Microvascular Angina, Leukoaraiosis, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Microvascular disease in type 2 diabetes, which manifests as white matter abnormalities on MRI, is associated with reduced cerebral BFVs, increased resistance in middle cerebral arteries, and inflammation.	16801574
Esophageal Stricture, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Endoscopy revealed an esophageal stenosis 35 cm aboral without signs of mucosal inflammation, that was dilated once.	16802012
Inflammation, Supraglottic edema, Vocal Cord Paralysis	Altered Intercellular Communication	This case report describes a case where cricothyroidotomy was used for elective ventilation for short period of 48 hours in a patient who had a vocal cord palsy, supraglottic oedema and inflammation.	16802498
Multiple Organ Failure, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	To overcome all the problems mentioned, CVICM must develop from a mainly consensus-oriented to a more evidence-oriented medicine; CVICM must find ways to improve the poorly validated hemodynamic monitoring concept by pulmonary artery catheter and look for additional, less invasive monitoring techniques and better monitoring parameters; CVICM must support the search for new and hopefully better pharmacotherapeutic agents and cardiovascular assist devices as presently available to support the failing heart and the impaired vascular system; and CVICM must also learn to control noncardiac processes like inflammation and multi-organ failure, which often are responsible for the fatal outcome of the ICU patient with cardiovascular disease.	16802527
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a role in all the phases of atherosclerosis, and increased production of the acute-phase reactant, C-reactive protein (CRP), predicts future cardiovascular events.	16803998
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation, longevity, and cardiovascular diseases: role of polymorphisms of TLR4.	16803999
Inflammation, Atherosclerosis	Altered Intercellular Communication	The role of inflammation in atherosclerosis is well recognized.	16804000
Pneumonitis	Altered Intercellular Communication	Exhaled breath condensate (EBC) is proving to be a technique which can sample markers of lung inflammation; however, many factors affect the collection process.	16804290
Inflammation, Asthma	Altered Intercellular Communication	In asthmatic patients with eosinophilic inflammation of the peripheral airways, appropriate drug delivery to the affected area is required.	16804291
Inflammation	Altered Intercellular Communication	Among the patients who underwent colonoscopy at the 5-year visit, symptoms were frequently reported in patients without macroscopic inflammation (44%).	16804390
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	Intestinal inflammation associated with Crohn's disease is characterized by a type 1 helper T cell response and elevated levels of interleukin (IL)-12.	16804392
Inflammation, Metaplasia, CEL gene	Altered Intercellular Communication	Levels of GSTs, glutathione and cysteine, and the degree of inflammation and colonic metaplasia were quantified in biopsies from the pouch and afferent loop of 26 patients with FAP.	16804871
Inflammation	Altered Intercellular Communication	No correlation was found between inflammation or colonic metaplasia of the pouch and GST enzyme activity in the pouch.	16804871
Inflammation, Dental Plaque, Gingival Hyperplasia	Altered Intercellular Communication	All subjects were clinically examined for plaque levels (plaque index), gingival inflammation (gingival index), and gingival enlargement.	16805671
Inflammation, Cryptosporidiosis, Diarrhea	Altered Intercellular Communication	This study has demonstrated the high prevalence of Cryptosporidium infections in the Venda region and its implications in causing diarrhea and inflammation.	16806189
Refractory anemias, Inflammation, physiopathological	Altered Intercellular Communication	Vascular dysfunction is evident in RA patients, even at the level of the cutaneous microcirculation, but improves as inflammation regresses.	16806231
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Endothelial dysfunction and systemic inflammation in persons with echolucent carotid plaques.	16807651
Inflammation, Electrocardiogram: myocardial infarction (finding), Endothelial dysfunction, Cerebrovascular accident	Altered Intercellular Communication	Elevated levels of markers of systemic inflammation and endothelial dysfunction are predictors for future myocardial infarction and stroke.	16807651
Granulomatous inflammation	Altered Intercellular Communication	A review of the clinical records revealed no obvious cause for the granulomatous inflammation, and we propose the term "idiopathic uterine granulomas."	16810061
Granulomatous inflammation, Granuloma	Altered Intercellular Communication	Although local and systemic causes of granulomatous inflammation should be excluded, granulomas in the myometrium and cervical stroma may occur without an obvious underlying cause.	16810061
Acute Coronary Syndrome, Thrombosis, Inflammation	Altered Intercellular Communication	The study EDIT-ACS (Endothelial Dysfunction, Inflammation and Thrombosis in Acute Coronary Syndromes) was set in the Cardiology Department of our Institute, and inclusions were performed between June-November 2004.	16812980
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Markers of inflammation are inversely related to physical activity and fitness in sedentary men with treated hypertension.	16814119
Inflammation	Altered Intercellular Communication	These results imply a role of inflammation or immunomodulatory mechanisms in the regulation of pressure wave reflections.	16814117
Degenerative polyarthritis, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Quantitative determination of steroid hormone receptor positive cells in the synovium of patients with rheumatoid arthritis and osteoarthritis: is there a link to inflammation?	16815861
Degenerative polyarthritis, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To find a quantitative relationship between the number of receptor positive cells and markers of inflammation, and to compare the two groups of patients with rheumatoid arthritis and osteoarthritis.	16815861
Degenerative polyarthritis, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	A total of 36 patients with rheumatoid arthritis (n = 17) and osteoarthritis (n = 19) were included, and receptor positive cells and cellular markers of synovial inflammation were quantified by immunohistochemistry and ELISA (interleukin 6 (IL6) and IL8).	16815861
Degenerative polyarthritis, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Patients with rheumatoid arthritis showed a higher degree of histologically determined inflammation compared with those with osteoarthritis.	16815861
Degenerative polyarthritis, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Quantitative determination of steroid hormone receptor positive cells in the synovium of patients with rheumatoid arthritis and osteoarthritis: is there a link to inflammation?	16815861
Inflammation, Edema, therapeutic hemodilution	Altered Intercellular Communication	Hemodilution and inflammation lead to edema and increased muscle compartment pressure after cardiac surgery.	16817288
Hepatitis	Altered Intercellular Communication	The IgG subclass profile of anti-HBs in chronic carriers was not changed with liver inflammation and was independent of sex and age, except in individuals with abnormal ALT and AST for whom anti-HBs IgG1 was not significantly higher than IgG3 (p > 0.05), in spite of that whose mean O.D.	16817770
Cerebrovascular, Inflammation	Altered Intercellular Communication	Inflammation has been reported to be involved in the pathogenesis of cerebrovascular dementias (CvDs).	16817867
Pneumonitis, Neoplasms	Altered Intercellular Communication	In our patient, an upper left lobectomy was only technically feasible instead of a lingulectomy alone because of the spread pulmonary inflammation and the depth of bronchial wall invasion by the tumor.	16818074
Inflammatory Bowel Diseases, Inflammation, Malnutrition, Osteoporosis	Altered Intercellular Communication	Children and adolescents suffering from inflammatory bowel disease (IBD) are at risk of developing osteoporosis as a result of treatment with corticosteroids as well as of nonsteroidal factors like inflammation and malnutrition.	16819376
Inflammation	Altered Intercellular Communication	Wear-resistant bearing materials may hypothetically reduce chronic inflammation in the pseudosynovial membrane as compared to less wear-resistant bearing materials such as polyethylene.	16819678
Granulomatous inflammation, Granuloma	Altered Intercellular Communication	Our study demonstrated that a granulomatous inflammation is a common finding in non-loose implants as early as 1 year after the operation not demonstrating a difference in macrophages and granuloma formation with the various bearing materials.	16819678
Inflammation, Carcinogenesis, Atherosclerosis	Altered Intercellular Communication	Human 15-lipoxygenase-1 (h15-LO-1), which metabolizes polyunsaturated fatty acids, is a highly regulated, tissue-specific, lipid-peroxidating enzyme that functions in physiological membrane remodeling and in the pathogenesis of atherosclerosis, inflammation, and carcinogenesis.	16820097
Inflammation, Dental Plaque	Altered Intercellular Communication	Systemic inflammation was assessed by serum C-reactive protein (CRP), soluble adhesion molecules levels and local plaque inflammatory activation by coronary thermography.	16820148
Inflammation, Vascular System Injuries	Altered Intercellular Communication	In the clinically quiescent heart transplant recipient, an elevated BNP concentration is associated with molecular patterns that point to ongoing active cardiac structural remodeling, vascular injury, inflammation, and alloimmune processes.	16820574
Inflammation, Neoplasms	Altered Intercellular Communication	Out of 407 TCCs, 119 (29.23%) presented inflammation within the tumor or the lamina propria.	16820911
Inflammation, Neoplasms	Altered Intercellular Communication	At 10 years follow-up, a statistically significant association was shown between the presence of inflammation within the tumor or lamina propria and the number of recurrences (p<0.0001).	16820911
Bladder Neoplasm, Inflammation	Altered Intercellular Communication	The Mann-Whitney test confirmed a statistically significant difference between superficial bladder tumors with inflammation and those without (26.3 vs 11.5 months, p<0.001).	16820911
Inflammation, Carcinoma	Altered Intercellular Communication	In terms of survival rate, a statistically significant difference was reported between carcinomas with and without inflammation (p=0.0261).	16820911
Inflammation, Neoplasms	Altered Intercellular Communication	On multivariate analysis, the presence of inflammation within the tumor was found to be an independent predictor of survival in patients with TCC of the bladder (p=0.027).	16820911
vascular inflammations, Coronary Artery Disease	Altered Intercellular Communication	Role of superoxide dismutase in vascular inflammation and in coronary artery disease.	16820996
Laxity, Traumatic injury	Altered Intercellular Communication	The high risk of anterior cruciate ligament (ACL) injuries in female athletes may be related to hormonal fluctuations resulting in an increased laxity of ligaments and muscles.	16821077
Inflammation	Altered Intercellular Communication	Adipose tissue is reported to contain monocyte-like pre-adipocytes, which may mature into macrophages, contributing to local inflammation.	16822853
Tissue damage, Inflammation, Carcinoma, Atrophic	Altered Intercellular Communication	We confirmed that PA and PIA are common findings in prostates with and without carcinoma, but the question of whether inflammation produces tissue damage and PA or whether some other insult induces the tissue damage and atrophy directly, with inflammation occurring secondarily, is still unresolved.	16824675
human MUC1 protein, Inflammation, Protein-Energy Malnutrition	Altered Intercellular Communication	Two of the most important risk factors for morbidity and mortality are protein-energy malnutrition (PEM) and inflammation.	16825027
Eosinophilic disorder, Inflammation, Fibrosis Assessment, Edema	Altered Intercellular Communication	Histological analysis showed increased eosinophilia and fragmentation of cardiomyofibrils, nuclear pyknosis and edema without fibrosis or significant inflammation, indicative of acute or subacute injury.	16825283
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	On histological examination of biopsy segments inflammation of stomach mucosa in average intensification and H. pylori infection was confirmed.	16825722
HAMA - Gastrointestinal Symptoms, Infection caused by Helicobacter pylori, Acute and chronic inflammation	Altered Intercellular Communication	In spite of lack of gastrointestinal tract symptoms, on endoscopy there were features of chronic active hemorrhagic inflammation of stomach mucosa with H. pylori infection.	16825722
Inflammation, Fibrosis Assessment, Canada, interstitial	Altered Intercellular Communication	When compared to CAN, ADAM19 was expressed to a similar extent in non-transplant-related interstitial and glomerular fibrosis, interstitial atrophy and inflammation.	16827870
Psychiatric	Altered Intercellular Communication	Dysfunction of central dopaminergic neurotransmission has been implicated in the pathogenesis of these psychiatric states.	16829779
Parkinson Disease, palladium	Altered Intercellular Communication	Based upon current basal ganglion models in Parkinson's disease (PD), flumazenil could normalize neuronal signaling at several different locations.	16830315
Inflammation, Tissue Adhesions	Altered Intercellular Communication	Histopathologically, the choroid and iris showed chronic inflammation, loss of choroidal melanocytes, and dense chorioretinal adhesions.	16831039
Inflammation, Chronic cholecystitis, Fibrosis Assessment, Gallbladder adenocarcinoma, Hyperplasia	Altered Intercellular Communication	Its genesis may be related to chronic cholecystitis: long-term inflammation causes regional hyperplasia and heterogeneity of the gland body, lead to focal or regional thickening of the gallbladder wall, and result in gallbladder adenocarcinoma with stromal fibrosis finally.	16831286
Inflammation, Fibrosis Assessment, Shoulder Pain	Altered Intercellular Communication	The role of the biceps tendon in the pathology of anterior shoulder pain after shoulder arthroplasty appears to be consistent with fibrosis and inflammation.	16831643
Inflammation, Dermatomyositis, Polymyositis	Altered Intercellular Communication	Signs of inflammation in both symptomatic and asymptomatic muscles from patients with polymyositis and dermatomyositis.	16831829
Inflammation, Paresis	Altered Intercellular Communication	To determine whether muscle weakness is correlated with inflammation, expression of interleukin 1alpha (IL1alpha) and major histocompatibility complex (MHC) class I and II antigens on muscle fibres.	16831829
Inflammation	Altered Intercellular Communication	Individual markers of inflammation may add incremental predictive value in the context of conventionally available risk factors.	16831981
Inflammation, dendritic lamellar body	Altered Intercellular Communication	Elevated levels of complement proteins and endothelial markers of inflammation were observed, which are similar to previous reports in DLB.	16832629
dendritic lamellar body, Nerve Degeneration	Altered Intercellular Communication	This study demonstrates that qualitatively similar inflammation-associated neurodegeneration is present in widespread regions of the brain in a RP case presenting clinically as DLB.	16832629
Inflammation, Hypertension, CTCAE, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Diabetes, obesity, and hypertension may enhance associations between air pollution and markers of systemic inflammation.	16835049
Inflammation, Hypertension, CTCAE, Obesity, Diabetes Mellitus	Altered Intercellular Communication	We found modest positive associations between PM2.5 and indicators of systemic inflammation, with larger associations suggested for individuals with diabetes, obesity, hypertension, and elevated mean inflammatory markers.	16835049
Inflammation, Malnutrition	Altered Intercellular Communication	This case provides important information that enhances our understanding of lipid metabolism under conditions of malnutrition and inflammation.	16835471
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by inflammation of the lung in association with airflow obstruction.	16836700
ARCN1 gene, Inflammation	Altered Intercellular Communication	There is increasing evidence of upper airway involvement in COPD and we have reported that this nasal inflammation is proportional to that in the lung.	16836700
Airway structure, ARCN1 gene, Nasal obstruction present finding	Altered Intercellular Communication	Given recognized relationships between lower airway inflammation and spirometric indices such as the Forced Expiratory Volume in one second (FEV(1)), we hypothesized that there may be a relationship between nasal obstruction and FEV(1) in COPD.	16836700
PROS1 gene, Inflammation, Nail Diseases	Altered Intercellular Communication	The purpose of this study was to explore the microanatomical basis for the inflammation and nail disease in PsA using a combined high-resolution magnetic resonance imaging (MRI) and histological studies.	16837473
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	This extended to involve the soft tissues adjacent to the nail in 8 of 10 cases in PsA, but only 4 of 10 cases in OA where the inflammation is less intense and in none of the normal fingers.	16837473
Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	The MER receptor tyrosine kinase (MERTK) gene is critical for the efficient clearance of apoptotic cells and has implications for inflammation and autoimmune diseases such as systemic lupus erythematosus (SLE).	16837475
Inflammation, Bacterial Infections	Altered Intercellular Communication	However, it is not known whether sTREM-1 measurements can distinguish milder bacterial infections from noninfectious inflammation.	16837506
organic disease, Gastrointestinal inflammation	Altered Intercellular Communication	Calprotectin and lactoferrin in the assessment of intestinal inflammation and organic disease.	16838143
Crohn Disease, Inflammation, Ulcerative Colitis, Colitis	Altered Intercellular Communication	Fecal excretion of calprotectin significantly correlated with the finding of colonic inflammation at endoscopy, both in ulcerative colitis and in Crohn's disease (p<0,001 and p<0,008, respectively), while lactoferrin excretion significantly correlated with histological inflammation (p=0.001 and p=0.009 respectively).	16838143
Inflammation, diabetic	Altered Intercellular Communication	In conclusion, type 2 diabetic patients with MS have elevated markers of inflammation and evidence of cardiac sympathetic predominance.	16839835
Inflammation, Sleep Apnea, Obstructive, Hypoxia	Altered Intercellular Communication	Intermittent hypoxia is the strongest predictor of TNF-alpha levels, supporting a role for inflammation in the cardiovascular pathophysiology of OSAS.	16840748
Endocrine Gland Neoplasms, Neoplasms	Altered Intercellular Communication	It is well known that some procedures performed in diagnostic and therapeutic management of endocrine tumors, such as agobiopsy and hepatic chemoembolization, can be associated with the occurrence of symptoms related to the release of vasoactive amines and/or hormonal peptides from tumor cell lysis.	16840837
Inflammation, Cancer of Nose	Altered Intercellular Communication	Nasal and paranasal cancers in Tunisia are linked more to chronic rhino-sinusal inflammation than professional exposition (wood).	16840900
Granulomatous inflammation, Intestine Resection	Altered Intercellular Communication	Histopathological examination of resected bowel tissue revealed granulomatous inflammation, and acid-fast bacilli were seen with appropriate staining.	16841591
Granulomatous inflammation, Nontuberculous Mycobacteria Measurement, Tuberculosis	Altered Intercellular Communication	Following an excision biopsy of the lesion, the histopathology report revealed a mass of lymph nodes with granulomatous inflammation strongly suggestive of infective aetiology, most probably of mycobacterial (either tuberculosis or non-tuberculous mycobacteria (NTM)) origin.	16841612
Granulomatous inflammation, Nontuberculous Mycobacteria Measurement, Tuberculosis, Cervical lymphadenitis	Altered Intercellular Communication	We discuss the significance of caseating granulomatous inflammation in cervical lymphadenitis and provide a brief overview of tuberculosis and a comparison with NTM.	16841612
Inflammation, Ulcer	Altered Intercellular Communication	Capsule endoscopy in patients with non-conventional indications yielded abnormal pathology, such as ulcers and inflammation.	16842455
Gingivitis, Inflammation, Periodontitis	Altered Intercellular Communication	The local production of IL-1beta and IL-18 in the gingival crevicular fluid increased with increasing inflammation and IL-18 was the predominant cytokine at both gingivitis and periodontitis sites.	16842511
Inflammation, Atherosclerosis	Altered Intercellular Communication	The cardinal role of chronic inflammation in the development of atherosclerosis is increasingly being recognized.	16842799
Orthostatic intolerance	Altered Intercellular Communication	Different orthostatic intolerance syndromes may show important hormonal, autonomic and hemodynamic differences during supine rest and enhanced after passive orthostatism.	16843544
Inflammation, Depression, CTCAE, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Recent research data suggest that inflammation and/or depression are associated with the development and progression of cardiovascular disease (CVD).	16844277
Inflammation	Altered Intercellular Communication	These findings indicate that irrational beliefs are associated with increased inflammation process, among apparently healthy individuals.	16844277
Granulomatous inflammation, Granulomatous, Necrosis	Altered Intercellular Communication	Biopsy findings showed granulomatous inflammation with foci of dermal necrosis suggestive of a BCG-related granulomatous reaction.	16844523
Inflammation, Fibrosis Assessment, Mesothelial hyperplasia, Diverticulum, Hypertrophy	Altered Intercellular Communication	Sections 4 mum thick were cut, stained with hematoxylin and eosin, and examined for the following parameters: fibrosis, myolysis, inflammation, nuclear size, pericardial exudates, lipofuscin pigment, arteriolar hypertrophy, contraction banding, mesothelial hyperplasia, and atrial diverticula.	16844552
Inflammation	Altered Intercellular Communication	Histopathologic examination showed chronic inflammation of the trabecular meshwork and angle closure.	16845263
Cranial nerve palsies, Pituitary Apoplexy	Altered Intercellular Communication	Pituitary apoplexy should be considered a cause of acute isolated sixth cranial nerve palsy and may represent a life-threatening emergency that can be averted with emergent hormonal replacement and hypophysectomy.	16845307
Pancreatic carcinoma	Altered Intercellular Communication	Evaluation of an inflammation-based prognostic score in patients with inoperable pancreatic cancer.	16847382
Pancreatic carcinoma	Altered Intercellular Communication	The present study assesses the value of an inflammation-based score (Glasgow Prognostic Score, GPS) in patients with inoperable pancreatic cancer.	16847382
Swelling, Orbital Pseudotumor	Altered Intercellular Communication	These changes are characterized by different stages of orbital inflammation, swelling and passive congestion.	16848193
Retrobulbar Route of Drug Administration, Exophthalmos, Orbital Pseudotumor	Altered Intercellular Communication	No infiltrative or inactive stage of the disease is most commonly seen in younger population as mild, orbital inflammation, lid retraction, variable proptosis and retro bulbar discomfort.	16848193
Cornea, Compression of optic nerve, Conjunctival hyperemia, Retrobulbar Route of Drug Administration, Retraction of eyelid, Orbital Pseudotumor, Unspecified visual loss, physiopathological, Exophthalmos	Altered Intercellular Communication	Infiltrative or active stage of the disease usually affects older people and is characterized by a broad spectrum of clinical symptoms such as moderate or severe orbital inflammation, retro bulbar pain, lid retraction, periocular edema, proptosis with corneal exposure, extra ocular muscle dysfunction, conjunctival and episcleral congestion and optic nerve compression with loss of visual acuity.	16848193
Intraocular inflammation, Traumatic injury	Altered Intercellular Communication	Eyes with a history of ocular trauma, surgery or intraocular inflammation were excluded.	16848204
Nonalcoholic Steatohepatitis, Inflammation, Fatty degeneration, Hepatobiliary Disorder, Fatty Liver Disease	Altered Intercellular Communication	Nonalcoholic steatohepatitis (NASH) is a liver disease characterized by steatosis and periportal and lobular inflammation.	16848812
Inflammation, Fibrosis Assessment, Fatty degeneration, Steatohepatitis	Altered Intercellular Communication	We investigated chitotriosidase gene expression in Kupffer cells to determine the potential implication of this enzyme in the inflammation and in the progression from uncomplicated steatosis to steatohepatitis with progressive fibrosis.	16848812
methyldopa, Inflammation	Altered Intercellular Communication	The evidence that inflammation is an important pathway in age-related macular degeneration (AMD) is growing.	16849663
Inflammation, Neoplasm Metastasis, Lymphoma	Altered Intercellular Communication	OBS provided false positive data in 3 patients (metastasis, chronic inflammation, lymphoma).	16850106
Granulomatous inflammation, Adenolymphoma	Altered Intercellular Communication	Granulomatous inflammation occurring in Warthin's tumor is a rare phenomenon.	16850483
Adenolymphoma, Granulomatous inflammation	Altered Intercellular Communication	We studied cases of Warthin's tumor with granulomatous inflammation to analyze the possible relationship with prior FNA.	16850483
Granulomatous inflammation, Adenolymphoma	Altered Intercellular Communication	Granulomatous inflammation was noted in 6 cases (1.6%) of 382 cases of Warthin's tumor in a medical center.	16850483
Granulomatous inflammation, Adenolymphoma	Altered Intercellular Communication	The pathogenesis of granulomatous inflammation in Warthin's tumor remains speculative.	16850483
Presenile dementia, Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation plays a role in the pathogenesis of dementia and Alzheimer's disease (AD).	16854501
Inflammation, polychondritis, Cartilage	Altered Intercellular Communication	A diagnosis of relapsing polychondritis was made based on positive serum antibodies to type II collagen and a wedge biopsy which revealed areas of cartilage necrosis and focal areas of perichondral inflammation with lymphocytes and histiocytes.	16854756
Inflammation, Pain Distress Question	Altered Intercellular Communication	During his last clinic follow up, 17 months after beginning mycophenolate mofetil, our patient had no subjective symptoms and objectively had no inflammation or pain to palpation.	16854756
Inflammation, Eye Movements, Chemosis of conjunctiva, Facial swelling (finding), Exophthalmos	Altered Intercellular Communication	Severe periocular inflammation can result from retrobulbar chlorpromazine injection and may manifest as chemosis, proptosis, limited ocular motility, and facial swelling that may extend well beyond the eyelids.	16855501
Inflammation	Altered Intercellular Communication	Examination disclosed bilateral firm, immobile, nontender masses in the lacrimal sac fossa with no associated signs of inflammation.	16855504
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	The concentration of RANTES is increased at inflammation sites in different autoimmune diseases.	16855620
Inflammation, Necrosis	Altered Intercellular Communication	Histopathologic examination of the specimen showed granulomatous inflammation of the testis and epididymis with prominent angiocentric granulomata in the walls of arteries, veins and foci of fibrinoid necrosis, surrounded by palisading inflammatory cells with a few giant cells.	16855769
Masticatory muscles	Altered Intercellular Communication	Authors concluded that the presence of masticatory muscle pain and/or TMJ inflammation can play a role in maximum bite force.	16856953
Inflammation	Altered Intercellular Communication	In Case 2 inflammation at the site of the cochlear implant was confirmed by performing a positron emission tomography scan, which showed an increased uptake.	16858576
Inflammation, Soft Tissue Infection, Fasciitis, Necrosis	Altered Intercellular Communication	Necrotising fasciitis is a rare, life-threatening, soft-tissue infection characterised by rapidly spreading inflammation and subsequent necrosis of the muscle, fascia and surrounding tissues.	16858757
Inflammation, Periodontitis, Dental caries, diabetic	Altered Intercellular Communication	Mucosal inflammation, dental caries, loose teeth, periodontitis were observed in the diabetic patients, whereas the oral cavities were generally in better condition in the control patients.	16859022
Cockayne Syndrome, Werner Syndrome	Altered Intercellular Communication	Werner Syndrome as an example of inflamm-aging: possible therapeutic opportunities for a progeroid syndrome?	16859481
Williams Syndrome	Altered Intercellular Communication	In this paper, the authors discuss the possibility that WS is an example of "inflamm-aging," in that many of the phenotypic manifestations may result from an increased inflammatory state.	16859481
Inflammation, Williams Syndrome	Altered Intercellular Communication	Recent data have indicated that fibroblasts derived from individuals with WS have activated a major molecular pathway involved in inflammation.	16859481
Inflammation, Williams Syndrome	Altered Intercellular Communication	Moreover, drugs that specifically block this inflammation pathway may be possible candidates for therapeutic intervention in WS.	16859481
Autoimmune Diseases, Inflammation, Chagas Disease	Altered Intercellular Communication	Chagas disease is characterized by chronic inflammation similar to autoimmune diseases.	16859784
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	High-sensitivity C-reactive protein (hsCRP) and soluble cluster of differentiation 40 ligand (sCD40L) have been established as effective markers of inflammation in predicting the risk for adverse outcomes in patients with acute coronary syndromes (ACSs).	16860169
Hyperplasia, Hyperparathyroidism, Secondary, Chronic Kidney Diseases, HYPERPARATHYROIDISM, NEONATAL SEVERE	Altered Intercellular Communication	Secondary hyperparathyroidism (SHPT) is a severe and frequent complication in patients with advanced chronic kidney disease, characterized by hyperplasia of all parathyroid glands and elevated serum parathyroid hormone levels.	16860201
Inflammation, Cardiovascular morbidity, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation is an important predictor of increased cardiovascular morbidity and mortality in patients with chronic kidney disease (CKD), but the mechanisms behind the chronic activation of the immune system are not clearly understood.	16861246
Hypernatremia, Inflammation, Endotoxemia, Chronic Kidney Diseases	Altered Intercellular Communication	We hypothesize that fluid overload is associated with signs of systemic inflammation and endotoxaemia in stages 1-5 CKD patients.	16861246
Hypernatremia, Inflammation, Endotoxemia, Chronic Kidney Diseases	Altered Intercellular Communication	In summary, although most CKD patients presented signs of fluid overload that was associated with endotoxaemia, there was no association between endotoxaemia and systemic inflammation, suggesting the endotoxaemia may not be the main determinant of the inflammatory status in this group of patients.	16861246
Inflammation, Osteopenia	Altered Intercellular Communication	Stress and inflammation as a detrimental combination for peri-implant bone loss.	16861287
Inflammation, Osteopenia	Altered Intercellular Communication	While stress and inflammation alone may not necessarily be detrimental factors, the presence of stress heightens peri-implant bone loss significantly as inflammation increases.	16861287
Inflammation, Peptic Esophagitis	Altered Intercellular Communication	Scattered eosinophils in the distal esophagus traditionally provide the hallmark for peptic esophagitis, but the upper limit of eosinophils and the longitudinal extent of peptic inflammation along the esophagus are unknown.	16863575
Inflammation, Urinary tract infection	Altered Intercellular Communication	Histopathologic examination of intestines of groups with meconium and meconium plus 50 U/mL UTI showed serosal thickening, inflammation, focal fibrin, and collagen deposits.	16863846
Diversion procedure, Typhlitis, Small bowel obstruction, Stenosis Morphology	Altered Intercellular Communication	Laparotomy revealed partial small bowel obstruction caused by ileocecal inflammation with stenosis, and a perforated appendix with fistulization into the cecum.	16863859
Intraocular inflammation	Altered Intercellular Communication	Recurrent intraocular inflammation after implantation of the Artiflex phakic intraocular lens for the correction of high myopia.	16863981
Inflammation, Hyperglycemia, diabetic, Obesity, atherosclerotic	Altered Intercellular Communication	This study indicates that increased level of proinflammatory markers occurs in type 2 DM even in the absence of obesity and marked hyperglycaemia, confirming that the inflammation course of the atherosclerotic process is more severe in diabetic patients than in nondiabetic subjects.	16864902
vascular inflammations, Atherosclerosis, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Intra-vascular ultrasound also revealed diffuse coronary atherosclerosis progression for her age, which might result from SLE and APS, including vascular inflammation.	16864946
Inflammation, Hemorrhage, Ulceration, CTCAE	Altered Intercellular Communication	Surgical findings suggest that symptoms of the patient were due to ulceration, inflammation, or bleeding caused by acid-peptic juice secreted from ectopic gastric mucosa.	16864961
vascular inflammations, Endothelial dysfunction	Altered Intercellular Communication	Endothelial dysfunction (ED) and markers of vascular inflammation may be more appropriate for risk estimation.	16864964
Cessation of life, Inflammation	Altered Intercellular Communication	Because melanocortins and their receptors are significant modulators of inflammation, we hypothesized that downregulation of melanocortin receptors during brain death could contribute to enhance inflammation.	16864968
Inflammation, carotid aneurysm, Traumatic injury, Blood Coagulation Disorders	Altered Intercellular Communication	Reported causes include trauma, surgery, retropharyngeal inflammation, carotid aneurysm, aberrant artery at the thoracic inlet and bleeding diathesis.	16865216
Esophageal mucous membrane	Altered Intercellular Communication	Savara-Muller's classification was used for oesophageal mucosa inflammation evaluation, whereas gastric and duodenal mucosa inflammation were assessed according to Tytgat.	16865941
Acute and chronic inflammation	Altered Intercellular Communication	Duodenal mucosa demonstrated traits of chronic active inflammation in 8 children and chronic in 5 of them.	16865941
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Candida fungi may be an etiopathogenetic factor of oesophageal, gastric and duodenal mucosa inflammation, Candida-induced mucosa inflammation is most frequently of chronic nature.	16865941
Stomach Diseases, Inflammation, Myocardial Ischemia	Altered Intercellular Communication	Erosive gastropathy is accompanied by the activity of the chronic inflammation response in the duodenum mucous coat that is most evident in IHD patients.	16866261
Inflammation, Depressed mood	Altered Intercellular Communication	This impaired cortisol response might contribute to chronic inflammation (as reflected in the elevated C-reactive proteins in depressed patients) and in other ways increase CVD risk.	16868262
Inflammation, Vascular Access Graft Failure	Altered Intercellular Communication	The role of mineral metabolism and inflammation on dialysis vascular access failure.	16868901
Inflammation, Thrombosis, Disorder of mineral metabolism	Altered Intercellular Communication	These results, which confirm that VA thrombosis occurs more frequently upon preexisting stenosis, also demonstrate that mineral metabolism disorders, compared to inflammation, may contribute to VA dysfunction leading to thrombosis.	16868901
Pain Distress Question, Inflammation, Traumatic injury	Altered Intercellular Communication	Local cryotherapy is used to relieve pain and inflammation in injuries and inflammatory conditions.	16870097
Refractory anemias, Pain Distress Question, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	The aim of the study was to compare the effect of cryotherapies on pain and inflammation in patients with rheumatoid arthritis (RA).	16870097
Pain Distress Question, Inflammation, Traumatic injury	Altered Intercellular Communication	Local cryotherapy is used to relieve pain and inflammation in injuries and inflammatory conditions.	16870097
Inflammation, Cognition Disorders	Altered Intercellular Communication	We present information from a series of 1136 consecutive patients presenting with cognitive disorders and show possible significant contribution of toxic environmental and occupational exposures to pathological aging (21% of patients) and interactions of these exposures with common polymorphisms that affect cell injury and inflammation.	16870258
Inflammation, Infection	Altered Intercellular Communication	APOE, Hfe, and AAT genes are expressed in liver tissue and in macrophages and are involved in the host innate immune response to stress, inflammation and infections.	16870258
Neurodegenerative Disorders, Inflammation, cell injury	Altered Intercellular Communication	Common genetic polymorphisms that affect the response to inflammation and cell injury provide a beginning strategy for dissecting neurodegenerative disorders.	16870258
Communicable Diseases, Rhinosinusitis, Inflammation	Altered Intercellular Communication	Although multiple etiologies contribute to the development of rhinosinusitis, a common pathophysiological sequelae is ineffective sinonasal mucociliary clearance, resulting in stasis of sinonasal secretions, with subsequent infection, and persistent inflammation.	16871938
Communicable Diseases, Inflammation	Altered Intercellular Communication	Thus, diminished or absent adaptation could predispose the sinonasal cavity to accumulation of inhaled infectious and noxious particulate matter resulting in infection/inflammation.	16871938
Colitis	Altered Intercellular Communication	Most patients showed mild, non-specific colonic inflammation.	16872318
Inflammation	Altered Intercellular Communication	The histopathology of the AlphaCor-corneal complex is characterized by mild inflammation in the corneal tissues, limited to the region surrounding the anteriorized and extruded part of the KPro.	16872343
Communicable Diseases, Inflammation, Choroidal Neovascularization, Traumatic injury	Altered Intercellular Communication	Choroidal neovascularization in children is uncommon and mostly associated with inflammation, infectious diseases or trauma.	16872344
Inflammation, Atherosclerosis	Altered Intercellular Communication	If chronic inflammation plays a causal role in atherogenesis, individuals with proinflammatory gene variants would be expected to develop more atherosclerosis.	16873708
Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	These results provide support for a causal role of inflammation in carotid atherosclerosis, and emphasize the importance of gene-gene and gene-environment interactions in this pathogenic pathway.	16873708
Carotid Atherosclerosis	Altered Intercellular Communication	Genetic and acquired inflammatory conditions are synergistically associated with early carotid atherosclerosis.	16873708
Communicable Diseases	Altered Intercellular Communication	We replicated this finding in a second large population and extended the analysis by inclusion of other inflammatory conditions (chronic infection and obesity/abnormal glucose tolerance).	16873708
Hyperglycemia, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Diabetes, hyperglycemia, and inflammation in older individuals: the health, aging and body composition study.	16873800
Obesity, Diabetes Mellitus	Altered Intercellular Communication	After adjustment for obesity, fat distribution, and inflammation-related conditions, IL-6 remained significantly related to both diabetes and IFG/IGT.	16873800
Inflammation, diabetic	Altered Intercellular Communication	Among diabetic participants, higher levels of HbA(1c) were associated with higher levels of all three markers of inflammation, but only CRP remained significant after full adjustment.	16873800
Inflammation, Dysglycemia, diabetic	Altered Intercellular Communication	Our findings show that dysglycemia is associated with inflammation, and this relationship, although consistent in diabetic individuals, also extends to those with IFG/IGT.	16873800
nervous system disorder, Inflammation, Myelinolysis, Central Pontine	Altered Intercellular Communication	Central pontine myelinolysis (CPM) is a neurologic disorder, consists of demyelinisation without inflammation in the base of pons, with a relative sparing of the axons and the nerve cells.	16875164
Primary physiologic amenorrhea	Altered Intercellular Communication	[Primary amenorrhea: constitutional delayed puberty or hormonal disturbance].	16875262
Inflammation	Altered Intercellular Communication	He underwent exploratory surgery, which provided the following findings: sclerotrophic gallbladder with intense surrounding inflammation.	16875521
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Maximum oxygen uptake at peak exercise in elderly patients with coronary artery disease and preserved left ventricular function: the role of inflammation on top of tissue Doppler-derived systolic and diastolic function.	16875912
Inflammation	Altered Intercellular Communication	Chondroid tissue was surrounded by a dense concentration of chronic inflammation cells.	16876045
Inflammation, Cellulitis	Altered Intercellular Communication	Ultimately, there is localized inflammation or cellulitis over the swollen, tortuous artery.	16876061
palladium	Altered Intercellular Communication	Our data suggest that at least three genes involved in neurotransmitter systems may have more specific role in genetic predisposition to PD.	16876316
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation and oxidative stress have been implicated in the pathogenesis of atrial fibrillation (AF).	16876733
Inflammation	Altered Intercellular Communication	Two eyes that had delayed epithelial healing because of graft override with stromal inflammation underwent a second surgery (penetrating keratoplasty).	16877068
Inflammation, Uveitis	Altered Intercellular Communication	Poor visual acuity in patients with CME was associated with the advanced age of the patients, chronic inflammation, and various specific uveitis entities.	16877081
Anxiety, CTCAE 3.0, Actual Impaired Interactive Behavior	Altered Intercellular Communication	These mice also display deficits in hippocampal synaptic transmission and impaired behavior characterized by increased anxiety, delayed learning from 3 months, and reduced spatial memory at 10 months.	16877359
Destruction of tissue, Inflammation	Altered Intercellular Communication	Proteinase-3 (PR3) is an abundant serine proteinase stored in the azurophilic granules of neutrophils and released to the cell surface upon activation where it contributes to local tissue destruction and inflammation.	16878019
Inflammatory Bowel Diseases, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The fact that this cancer is more common in patients suffering from inflammatory bowel disease raises the question of the relationship between chronic inflammation and cancer.	16879199
Crohn Disease, Colorectal Carcinoma, Ulcerative Colitis	Altered Intercellular Communication	Recent evidence about the association of polymorphisms in these genes with ulcerative colitis and Crohn's disease, as well as other inflammatory conditions, was the basis for our investigation of their role in sporadic colorectal cancer.	16879199
Inflammation, Rhinosinusitis	Altered Intercellular Communication	C4A null alleles are associated with chronic or recurrent rhinosinusitis, potentially through their effect on immune defence and inflammation control.	16879240
Inflammation, Prostate carcinoma, Prostatic Diseases	Altered Intercellular Communication	To assess whether colonization of the male urinary tract with Propionibacterium acnes, in particular types IB and II (which are associated with inflammation in radical prostatectomy specimens and might be involved in the development of prostate cancer), is associated with prostate disease, and thus to develop a urine test to detect men at risk of prostate disease.	16879683
Inflammation, Fever, CTCAE	Altered Intercellular Communication	The girl, 17 years-old, nothing else to arrive our hospitalary center required entrance in ICU due to her severe clinical process: High fever, intense neck-thoracic pain, laterocervical diffuse and progressive left inflammation and bad general state.	16881550
Inflammation, Chlamydia	Altered Intercellular Communication	The inflammation marker C-reactive protein was significantly and positively associated with level of antibodies to Chlamydia pneumoniae only in heavily exposed (>or=1000 mGy) survivors.	16881737
Inflammation, Pyuria	Altered Intercellular Communication	Inflammation was histologically detected at rates of 58.1% and 34.1% in the pyuria and non-pyuria groups, respectively (P = 0.0014).	16882055
prostatitis	Altered Intercellular Communication	The U-WBC count appears to be a reliable indicator of minute prostatic inflammation.	16882055
physiopathological, Diabetes Mellitus	Altered Intercellular Communication	Bone disease in hemodialysis patients with diabetes mellitus is characterized by low bone turnover, resulting from either impaired secretion of parathyroid hormone or osteoblast dysfunction.	16883043
Inflammation, Cardiac Tamponade, Pericardial Effusion, CTCAE	Altered Intercellular Communication	Blood test revealed inflammation and cardiac echography revealed pericardial effusion with a collapse sign of right atrium, thereby leading to the diagnosis of cardiac tamponade.	16883110
Edema of eyelid, Inflammation	Altered Intercellular Communication	The clinical examination showed a large palpebral edema extending to the side of the face, associated with local signs of inflammation.	16885887
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	This case shows that in chronic inflammation of the nasal vestibule that fails to respond to antibiotic treatment differential diagnostic consideration must be given to the possibility of a malignancy.	16886488
Endocrine System Diseases, Chronic Kidney Diseases	Altered Intercellular Communication	Among the numerous complications associated with chronic renal disease both bone and hormonal disturbances have long been recognized.	16886562
Maxillary Neoplasms	Altered Intercellular Communication	The second patient was a 58-year-old man who had undergone an operation (surgery) by reason of maxillary inflammation tumor in 2002 year.	16886569
Maxillary Neoplasms, Inflammation, Lymphoma	Altered Intercellular Communication	In 2004 year he underwent surgery on account of maxillary tumor suspected by malignant lymphoma, which was diagnosed as inflammation.	16886569
Lymphoma	Altered Intercellular Communication	The similar clinic and radiological symptoms and laboratory results of malignant lymphomas and inflammations of head and neck can cause the late diagnosis and aggravate the prognosis of this severe disease.	16886569
Celiac Disease, Autoantibodies, Inflammation	Altered Intercellular Communication	Coeliac autoantibodies in the serum or Marsh I inflammation may be indicators of subsequent coeliac disease.	16886921
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Neointimal inflammation and angiogenesis are important contributors of progression and destabilization of the atherosclerotic plaque.	16887107
Inflammation, Myocardial	Altered Intercellular Communication	Experimental data suggests that autoantibodies could promote myocardial damage by inducing either inflammation or alternatively, augmentation of Ca2+ currents or activation of surface receptors on cardiomyocytes.	16887211
Inflammation	Altered Intercellular Communication	Also, during inflammation SAF-1 transgenic mice exhibited a prolonged acute phase response, leading to an extended period of SAA synthesis.	16888022
Inflammation	Altered Intercellular Communication	Together, these results provide direct evidence that SAF-1 plays a key role in the development of AA amyloidosis, a consequence of chronic inflammation.	16888022
Brucellosis, Rheumatoid Arthritis, Amyloidosis, Angiolymphoid hyperplasia, Crohn Disease, Spondylitis	Altered Intercellular Communication	Abundantly expressed serum amyloid A (SAA) protein under chronic inflammatory conditions gives rise to insoluble aggregates of SAA derivatives in multiple organs resulting in reactive amyloid A (AA) amyloidosis, a consequence of rheumatoid arthritis, Crohn's disease, ankylosing spondylitis, familial Mediterranean fever, and Castleman's disease.	16888022
Inflammation, Choroidal Neovascularization	Altered Intercellular Communication	Angiotensin II type 1 receptor-mediated inflammation is required for choroidal neovascularization.	16888236
Inflammation	Altered Intercellular Communication	AT1-R-mediated inflammation plays a pivotal role in the development of CNV, indicating the possibility of AT1-R blockade as a novel therapeutic strategy to inhibit CNV.	16888236
Carotid Atherosclerosis, Inflammation, Atherosclerosis	Altered Intercellular Communication	Dental and periodontal status and risk for progression of carotid atherosclerosis: the inflammation and carotid artery risk for atherosclerosis study dental substudy.	16888276
Inflammation, Hyperparathyroidism	Altered Intercellular Communication	This indicates that hyperparathyroidism not only accelerates bone remodeling but may also aggravate inflammation in patients on maintenance hemodialysis.	16888370
Inflammation, Cancer Genetics Network, Chronic glomerulonephritis, Fibrosis Assessment	Altered Intercellular Communication	To measure urine and renal tissue levels of profibrogenic mediators (monocytic chemotaxic protein-1-MCP-1 and transforming growth factor beta1 - TGF-b1) in patients with chronic glomerulonephritis (CGN); to specify significance of these mediators for assessment of inflammation and fibrosis in the kidney and as prognosis criteria.	16889042
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	To further understand the role of neuro-immunological interactions in the pathogenesis of rheumatoid arthritis (RA), we studied the influence of sympathetic neurotransmitters on cytokine production of T cells in patients with RA.	16889669
Osteitis	Altered Intercellular Communication	However, immunolabelling of osteoblasts for NOS3 in biopsy tissues did not correlate with the carriage of a determined NOS polymorphism but with the presence of bone inflammation.	16889995
Inflammation	Altered Intercellular Communication	It is currently supposed that scarring of the dorsal root ganglia and atrophy of the dorsal horn as a result of intense inflammation may play a central role in the pathogenesis of this condition.	16890379
Inflammation, Superinfection, Herpes zoster disease, Neuralgia, Streptococcus	Altered Intercellular Communication	Since streptococcal and/or staphylococcal superinfection of skin lesions is common in herpes zoster, we present a hypothesis of immunopathogenesis of postzosteric neuralgia, i.e., as the result of augmentation of local ganglion inflammation due to bacteria-driven clonal expansion of VZV-specific T-cell subsets in the affected skin.	16890379
Celiac Disease, Inflammation	Altered Intercellular Communication	Celiac disease is a chronic inflammation of the duodenal mucosa driven by gluten-reactive T cells restricted by the disease-associated HLA-DQ2 molecule.	16890596
Inflammation, Carcinogenesis	Altered Intercellular Communication	The influence of chronic inflammation in prostatic carcinogenesis: a 5-year followup study.	16890681
Carcinogenesis, prostatitis	Altered Intercellular Communication	We investigated an association between chronic prostatic inflammation and prostate carcinogenesis.	16890681
Proliferative Inflammatory Atrophy, Hyperplasia, Chronic inflammation	Altered Intercellular Communication	Post-atrophic hyperplasia and proliferative inflammatory atrophy were noted only in patients with chronic inflammation.	16890681
Inflammation, Primary malignant neoplasm, Malignant Neoplasms	Altered Intercellular Communication	In repeat biopsies within 5 years in patients with chronic inflammation 29 new cancers were diagnosed, representing a new cancer incidence of 20%.	16890681
Prostatic Intraepithelial Neoplasias, Proliferative Inflammatory Atrophy, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Of these cancers 6 occurred in patients in whom initial biopsies showed only chronic inflammation, 15 occurred in patients with initial post-atrophic hyperplasia/proliferative inflammatory atrophy lesions, 7 occurred in patients with initial high grade prostatic intraepithelial neoplasia and chronic inflammation, and 1 occurred in a patient with initial atypical small acinar proliferation and chronic inflammation.	16890681
Inflammation, Prostatic Intraepithelial Neoplasias, Atrophic, Proliferative Inflammatory Atrophy	Altered Intercellular Communication	High grade prostatic intraepithelial neoplasia was newly discovered in 9 patients in the initial chronic inflammation group, of whom 7 had post-atrophic hyperplasia/proliferative inflammatory atrophy and 2 had simple atrophy and chronic inflammation in the initial biopsies.	16890681
Adenocarcinoma	Altered Intercellular Communication	In contrast, in 33 patients initially showing no inflammation adenocarcinoma was subsequently found in 2 (6%).	16890681
Inflammation, Adenocarcinoma of prostate	Altered Intercellular Communication	Chronic inflammation may be a significant risk factor for prostatic adenocarcinoma.	16890681
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Recent studies have suggested a link between chronic inflammation and development of prostate cancer.	16890703
Inflammation, Prostate carcinoma, prostatitis	Altered Intercellular Communication	We explored the chronic inflammation hypothesis of prostate cancer development among black men by examining sexual activity, sexually transmitted diseases and prostatitis in a population based study of 129 patients and 703 controls 40 to 79 years old.	16890703
Communicable Diseases, Inflammation, Prostate carcinoma, Infectious agent	Altered Intercellular Communication	Additional prospective research incorporating serological markers of infectious agents or predictive markers of chronic inflammation should serve to elucidate the possible causal pathway of recurring or persistent infection in the etiology of prostate cancer in black men.	16890703
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Cancer is also marked by abnormalities in platelet activation (marked by soluble P selectin) and inflammation (interleukin-6 [IL6]).	16891056
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	These may be linked pathogenically with coagulation and inflammation.	16891056
Refractory anemias, Inflammation, Synovitis	Altered Intercellular Communication	The analysis of the clinical data revealed that RA patients with a histopathologic type II synovitis and synovial tissue collagenase 3 mRNA expression had elevated levels of systemic markers of inflammation and received stronger therapies.	16891219
Inflammation	Altered Intercellular Communication	Allogeneically transplanted islets from BB-DP rats were removed before onset of allograft rejection and at maximal islet graft inflammation (rejection).	16891220
Inflammation	Altered Intercellular Communication	These results indicate that low-grade inflammation may play a role in the modulation of arterial BP relatively early in life.	16891995
Inflammation	Altered Intercellular Communication	Etoricoxib was safe for treating inflammation in patients with AERD.	16892790
Data types - Address	Altered Intercellular Communication	As glutamate is the principle excitatory neurotransmitter of the CNS, the glutamatergic system may play an important role in AD.	16893425
Parkinson Disease, Inflammation, palladium	Altered Intercellular Communication	The authors studied the association of markers of inflammation with the later development of Parkinson disease (PD) using a case-control design (196 cases and 196 matched controls).	16894114
Atherosclerosis	Altered Intercellular Communication	Furthermore IFN-alpha released in chronic inflammatory conditions might contribute via its prosenescent activity to the pathogenesis of atherosclerosis.	16894355
Trachoma , Inflammation	Altered Intercellular Communication	All children 1-10 years of age from the selected households were examined for the presence of active trachoma (trachomatous follicles, TF, and trachomatous intense inflammation, TI).	16895035
Glaucoma, Primary Open Angle, Inflammation	Altered Intercellular Communication	Primary open-angle glaucoma (POAG) is a multifactorial disease, in which aging, race, genetic disposition, vascular status, probably inflammation, and maybe oxidative stress may play a specific role.	16896683
Ischemia, Inflammation, Osseous metaplasia, Necrosis, Sclerosis, Traumatic injury	Altered Intercellular Communication	Early animal experiments in the twentieth century showed that bone metaplasia may be induced by epithelium of the urinary tract under certain conditions such as ischemia, inflammation, necrosis, sclerosis, and trauma.	16896762
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation is a major factor in the pathogenesis of asthma.	16897191
Inflammation, atherosclerotic, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation plays a crucial role in atherosclerotic processes and in acute coronary syndromes (ACS).	16897925
Intraocular inflammation	Altered Intercellular Communication	Pars plana vitrectomy, capsulectomy, and injection of intravitreal vancomycin were eventually performed, leading to complete resolution of the intraocular inflammation.	16898393
Inflammation, Reactive systemic amyloidosis	Altered Intercellular Communication	Secondary amyloidosis is usually a complication of chronic inflammation.	16898966
Ruptured abdominal aortic aneurysm, Inflammation	Altered Intercellular Communication	HLA-DR expression on monocytes and systemic inflammation in patients with ruptured abdominal aortic aneurysms.	16899122
Multiple Organ Failure, Inflammation	Altered Intercellular Communication	Severe systemic inflammation, leading to multi-organ failure, often occurs in these patients.	16899122
Inflammation, Necrosis	Altered Intercellular Communication	Histopathological findings showed lack of smooth and longitudinal muscles in dilated segments of the intestine with intact mucosa without any evidence of necrosis and inflammation.	16899190
ARCN1 gene, Inflammation, Pulmonary Hypertension	Altered Intercellular Communication	Systemic inflammation in patients with COPD and pulmonary hypertension.	16899829
ARCN1 gene, Inflammation, Pulmonary Hypertension	Altered Intercellular Communication	However, no data on the potential role of systemic inflammation in pulmonary hypertension secondary to COPD are available.	16899829
ARCN1 gene, Inflammation, Pulmonary Hypertension	Altered Intercellular Communication	Therefore, our aim was to investigate the degree of systemic inflammation reflected by circulatory levels of C-reactive protein (CRP), tumor-necrosis factor (TNF)-alpha, and interleukin (IL)-6 in COPD patients with and without pulmonary hypertension.	16899829
ARCN1 gene, Inflammation, Pulmonary Hypertension	Altered Intercellular Communication	We conclude that increases in Ppa in patients with COPD are associated with higher serum levels of CRP and TNF-alpha, raising the possibility of a pathogenetic role for low-grade systemic inflammation in the pathogenesis of pulmonary hypertension in COPD patients.	16899829
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Viscosity, hemostasis and inflammation in atherosclerotic heart diseases.	16899908
Inflammation, Atherosclerosis	Altered Intercellular Communication	Our data underline the central role of IL-6 in low-grade inflammation contributing to atherosclerosis and CVD.	16900203
Communicable Diseases, Inflammation, Traumatic injury	Altered Intercellular Communication	Chronic mild sterile (possibly autoimmune) inflammation of meninges (dura mater) can be caused by a preceding infection, as well as minor trauma of the head and/or back.	16901450
Chronic inflammation, Leukoplakia	Altered Intercellular Communication	The present study did not show any statistically significant correlations between chronic inflammations, TP53 mutations, exposure to carcinogens and vesical leukoplakia.	16903935
Inflammation, Arthritis, Fever, CTCAE	Altered Intercellular Communication	Initially, he presented large-joint arthritis of the right knee and heel, with clinical data of systemic inflammation, such as fever, increase in sedimentation rate and leucocytosis, during more than six weeks of evolution.	16904039
Benign Prostatic Hyperplasia, Inflammation, Necrosis	Altered Intercellular Communication	Inflammation and occasionally necrosis is observed in the prostate tissue from patients with benign prostate hyperplasia (BPH).	16904256
Prostate	Altered Intercellular Communication	The etiology of prostatic inflammation/necrosis is unknown, but bacteria may be involved.	16904256
Inflammation, Necrosis	Altered Intercellular Communication	Of 6 cnf1-positive samples, severe inflammation and necrosis were present in four and three samples, respectively.	16904256
Inflammation, Necrosis	Altered Intercellular Communication	Of eight E. coli-positive/cnf1-negative samples, five showed signs of severe inflammation and two showed severe necrosis.	16904256
Prostate	Altered Intercellular Communication	Further studies are needed to show that particular E. coli genotypes are involved in the development of prostatic inflammation/necrosis in BPH.	16904256
Necrosis with inflammation	Altered Intercellular Communication	In ALT responders the necro-inflammation score improved non-significantly compared to ALT non-responders.	16905220
Granulomatous inflammation, Hemorrhage, Pseudotumor, Cerebellar vermis structure	Altered Intercellular Communication	Histopathological examination showed numerous S. mansoni ova involved by granulomatous inflammation in necrotic-exudative phase, located mainly in the internal, granular layer of the cerebellum, creating a pseudotumor in the cerebellar vermis and a recent hemorrhage in the trunk.	16906255
Rheumatoid Arthritis, Metacarpophalangeal joint structure, Orchitis	Altered Intercellular Communication	Doppler sonographic comparative study on usefulness of synovial vascularity between knee and metacarpophalangeal joints for evaluation of articular inflammation in patients with rheumatoid arthritis treated by infliximab.	16906371
Inflammation, Crohn Disease	Altered Intercellular Communication	Reduced neutrophil migration during acute inflammation in Crohn's disease is associated with impaired production of appropriate chemoattractants.	16907898
Inflammation	Altered Intercellular Communication	Platelet-activating factor, a mediator of inflammation, is an HIV-induced neurotoxin secreted in the infected brain.	16908170
Inflammation, "Alzheimers Disease", Data types - Address, Tumor necrosis, Tissue injury	Altered Intercellular Communication	Functional polymorphisms in tumor necrosis factor alpha (TNF-alpha) and interleukin 10 (IL-10) can affect immune response, inflammation, tissue injury, and possibly the susceptibility to Alzheimer disease (AD).	16908746
Pneumonitis, Pulmonary Fibrosis	Altered Intercellular Communication	Our results confirm that heterozygosity for the mutation 173T may cause chronic inflammation of the lung or progressive pulmonary fibrosis.	16910460
Inflammation	Altered Intercellular Communication	We also examined laboratory findings for the two groups related to systemic inflammation and organ function.	16910477
Inflammation, Hyperkeratosis	Altered Intercellular Communication	Biopsies were investigated with respect to histological hyperkeratosis (thickness of stratum corneum), proliferation (Ki-67 antigen), keratinization (K10, filaggrin) and inflammation (CD3).	16911278
Hepatic inflammation, Hepatitis C, Hepatocarcinogenesis, FAM126A gene	Altered Intercellular Communication	Considering the strong relation between hepatocarcinogenesis and hepatic inflammation with chronic HCV infection, these differences indicate that hepatocarcinogenic mechanisms in PIVKA-II-predominant HCC may differ from those in AFP-predominant HCC.	16911460
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Allograft biopsies were performed yearly, analyzing grading of inflammation and staging of fibrosis.	16911463
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Accumulating evidence indicates that interleukin-8 (IL-8) plays a major role in the mucosal inflammation caused by Helicobacter pylori infection.	16911683
Granulomatous inflammation	Altered Intercellular Communication	The most striking and obvious feature seen in granulomatous inflammation on confocal microscopy is the presence of multinucleated giant cells (MGCs).	16911981
Granulomatous inflammation	Altered Intercellular Communication	Initial results indicate that trained observers can detect MGCs in granulomatous inflammation.	16911981
Scleritis, Tubulointerstitial nephritis and uveitis, Inflammatory abnormality of the eye	Altered Intercellular Communication	Although scleritis has not been reported as a tubulointerstitial nephritis-associated ocular inflammation, it may be part of the possible spectrum of ocular inflammation occurring as part of the TINU syndrome.	16911986
Inflammation, Suppurative otitis media, Rhinosinusitis	Altered Intercellular Communication	We studied the role of Haemophilus influenzae in ENT inflammation in children, in purulent otitis and rhinosinusitis in particular, basing on the results of microbiological investigations of microflora.	16912665
Inflammation, Coronary Arteriosclerosis, Coronary Artery Vasospasm, Angina Pectoris, Variant	Altered Intercellular Communication	Coronary atherosclerosis with inflammation gives rise to coronary vasospasm in the patients with coronary vasospastic angina.	16913438
Inflammation, Ulcerative Colitis, Acute appendicitis NOS (disorder)	Altered Intercellular Communication	Earlier studies suggest that appendectomy is associated with a substantially reduced risk of certain types of bowel inflammation such as ulcerative colitis, particularly where the underlying diagnosis is acute appendicitis.	16914396
Inflammation, Swelling	Altered Intercellular Communication	An independent radiologist then characterized implant degradation, and the presence of soft tissue inflammation and swelling during the resorption phase of the bioresorbable plate.	16915094
Inflammation, Swelling	Altered Intercellular Communication	At an average follow-up of 32 months, MRI assessment showed no evidence of soft tissue swelling or inflammation related to the resorption of a bioresorbable anterior plate in any of the 5 patients.	16915094
Inflammation, Swelling	Altered Intercellular Communication	Based on MRI assessment, these devices, at more than 2-year follow-up, did not indicate any local chronic inflammation or swelling resulting from their degradation.	16915094
Inflammation, Thrombosis, Atherosclerosis	Altered Intercellular Communication	Clinical atherosclerosis is also associated with these same risk factors and with biomarkers of inflammation, thrombosis, endothelial cell activation.	16915303
Inflammation, Thrombosis, Dyslipidemias	Altered Intercellular Communication	We conclude that selected biomarkers for endothelial function, thrombosis and dyslipidemia but not inflammation are associated with the degree of ED in this cross-sectional analysis.	16915303
Inflammation, Complement System Proteins	Altered Intercellular Communication	Establishment of an in-house ELISA and the reference range for serum amyloid A (SAA): complementarity between SAA and C-reactive protein as markers of inflammation.	16916504
Acute myocardial infarction, Inflammation	Altered Intercellular Communication	We found only slightly increased levels of SAA in early stage of type 2 diabetics, but highly increased levels of SAA were detected in patients with acute myocardial infarction, generally associated with intense inflammation.	16916504
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	At the early stage of type 2 diabetes associated with low inflammation, SAA was found to be complementary to CRP in test sensitivity.	16916504
Inflammation, Angina Pectoris	Altered Intercellular Communication	Association between inflammation, lipid and hemostatic factors in patients with stable angina.	16916537
Inflammation, Atherosclerosis	Altered Intercellular Communication	Moreover, inflammation has also been shown to play an important role in the pathophysiology of atherosclerosis.	16916537
Inflammation, Thrombosis	Altered Intercellular Communication	Our objective was to determine the association between inflammation, lipids and thrombosis in a group of patients with stable angina.	16916537
Inflammation	Altered Intercellular Communication	Macrophage migration inhibitory factor (MIF) and the monocytes surface receptor CD14 are involved in the development and maintenance of chronic inflammation.	16916546
Celiac Disease, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Epithelial distribution of tissue transglutaminase is specific for coeliac disease rather than due to a non-specific mucosal inflammation.	16916632
Inflammation, Dental Plaque	Altered Intercellular Communication	It is well known that the vulnerable atheromatous plaque has a thin, fibrous cap and large lipid core with associated inflammation.	16917091
Inflammation, Carotid Stenosis	Altered Intercellular Communication	It suggests that investigation of the contralateral side in patients with symptomatic carotid stenosis can demonstrate inflammation in 95% of plaques, despite a mean stenosis of only 46%.	16917091
Inflammation, Asthma	Altered Intercellular Communication	Airway remodeling and inflammation are characteristic features of adult asthma that are still poorly investigated in childhood asthma.	16917118
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis treatment is based largely on anatomic extent of inflammation and severity.	16917398
Inflammation, Vascular Diseases, Obesity	Altered Intercellular Communication	Subclinical inflammation has been proposed as a pathophysiologic mechanism linking obesity with vascular and metabolic disease.	16918582
Inflammation, Obesity	Altered Intercellular Communication	Thus, we sought to determine whether subclinical inflammation is an early complication of obesity in Native children.	16918582
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Subclinical inflammation is an early complication of childhood obesity in Native children and may foreshadow an increased burden of CVD and type 2 diabetes in the future.	16918582
Necrotizing granulomatous inflammation, Glomerulonephritis, Granulomatosis with polyangiitis, Vasculitis, CTCAE, Inflammatory disorder	Altered Intercellular Communication	Wegener's granulomatosis (WG) is a chronic inflammatory disease characterized by granulomatosis inflammation, systemic vasculitis and glomerulonephritis.	16918819
Inflammation, Ulceration, CTCAE, Neoplasms, Fibrosis	Altered Intercellular Communication	Characteristics studied were: tumour width, excision margins, histological subtype, Clark level, Breslow depth, tumour differentiation, inflammation, perineural and angio-invasive growth, ulceration and desmoplasia.	16918972
Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	The clinical parameters probing depth (PD), modified bleeding index (MBI), and modified plaque index (MPI) served as indicators for bone resorption and inflammation.	16919021
Airway structure, Inflammation, Asthma	Altered Intercellular Communication	Some cellular and soluble markers of inflammation in induced sputum have been used for studying airway inflammation in asthma.	16919829
Inflammation, Erosion lesion, Stenosis	Altered Intercellular Communication	In one patient (6.3%), capsule endoscopy revealed ileal erosions and inflammation and was retained in a stricture undetected by radiology.	16920049
Inflammation, Acute dacryocystitis	Altered Intercellular Communication	On initial presentation, 18 patients had inflammation, including 17 with canaliculitis and 1 with recurrent acute dacryocystitis.	16920195
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Recently identified associations of prostate cancer risk with several genes involved in innate immunity support a role of inflammation in the etiology of prostate cancer.	16921508
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Considering inflammation is regulated by a complex system of gene products, we hypothesize sequence variants in many other genes of this pathway are associated with prostate cancer.	16921508
Inflammation, Cardiac complication, Electrocardiogram: myocardial infarction (finding), Diabetes Mellitus	Altered Intercellular Communication	Oxidative stress and increased inflammation have been reported to be increased in subjects with diabetes and to be involved in the pathogenesis of cardiovascular complications after myocardial infarction (MI).	16922703
Hemorrhage, Pelvic Inflammatory Disease	Altered Intercellular Communication	After surgical abortion, pelvic inflammation and bleeding were observed in 3.1% and 2.2%, respectively, with centre differences.	16923084
Inflammation	Altered Intercellular Communication	These represent broad categories of proteins involved with natural defenses, inflammation, growth, and coagulation.	16923417
Refractory anemias, Inflammation, Lymphoma	Altered Intercellular Communication	The role of chronic inflammation and methotrexate in the pathogenesis of lymphoma in RA was discussed.	16923515
Schistosomiasis japonica, Inflammation, Anemia	Altered Intercellular Communication	Schistosoma japonicum reinfection after praziquantel treatment causes anemia associated with inflammation.	16923790
Airway structure, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	Airway hyper-responsiveness (AHR) to adenosine 5'-monophosphate (AMP) is closely associated with airway inflammation; however, not all asthmatic patients are responsive to it.	16925688
Acute inflammation, Diabetes Mellitus	Altered Intercellular Communication	A multivariate Cox regression analysis showed that, over the follow-up period, diabetes mellitus was associated with a decreased risk of Nd:YAG capsulotomy (hazard ratio [HR]=0.69; 95% confidence interval [CI] 0.47-0.99; P=0.047), whereas age of 65 years or younger (HR=1.58; 95% CI 1.09-2.27; P=0.02), polymethylmethacrylate (PMMA) (HR=3.98; 95% CI 1.60-9.95; P=0.003) or plate-haptic silicone IOLs (HR=3.75; 95% CI 1.60-8.80; P=0.002) in comparison with three-piece silicone IOLs, postoperative inflammation (HR=2.62; 95% CI 1.56-4.42; P<0.001) and pars plana vitrectomy (HR=1.85; 95% CI 1.20-2.83; P=0.005) were associated with an increased risk.	16925699
Inflammation, Swelling	Altered Intercellular Communication	Except for local swelling and inflammation, no side effects occurred.	16928243
Inflammation	Altered Intercellular Communication	It seems that the anti-cancer agent evoked inflammation at the visceral pleura and the subject inhaled massive air flow into the systemic circulation.	16928561
Inflammation, Angina, Unstable	Altered Intercellular Communication	Our data show that, in patients with unstable angina there is an increase of platelet reactivity in response to ADP/collagen stimulation, which is not related to inflammation.	16928607
Inflammation, Hypoxia, Anemia, hepcidin	Altered Intercellular Communication	Hepcidin is a small defensin-like peptide whose production by hepatocytes is modulated in response to anemia, hypoxia, or inflammation.	16929540
Renal Insufficiency, Inflammation, hepcidin	Altered Intercellular Communication	Elevated hepcidin in all groups of patients studied may be due to low grade inflammation, frequently encountered in this population and mainly to impaired renal function.	16929540
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Clearance of HCV did not correlate with age (p = 0.65), sex (p = 0.13), past HBV infection (n = 22 anti-HBc +) (p = 0.24), maximum pre-treatment ALT activity (p = 0.06), grade of inflammation (p = 0.33) or stage of fibrosis (p = 0.9) in liver biopsy.	16929613
Inflammation, Epstein-Barr virus encoded RNA 1, Ulcer	Altered Intercellular Communication	There was inflammation including numerous plasma cells in the ulcer bases and surrounding areas, where many EBV-infected plasma cells were detected by double staining with EBV-encoded small RNA-1 (EBER-1) in situ hybridization and CD79a, while EBV-infected epithelial cells were not noted.	16930333
Alzheimers Disease", Inflammation	Altered Intercellular Communication	Genetic risk profiles for Alzheimer's disease: integration of APOE genotype and variants that up-regulate inflammation.	16930778
Kidney Glomerulus, Inflammation	Altered Intercellular Communication	Apoptotic rate is greater in severe active glomerular lesions in human LN, suggesting that apoptosis may be involved in augmenting inflammation in human LN.	16931214
Airway structure, Asthma	Altered Intercellular Communication	In patients with asthma, CHRM1 may be involved in airway constriction, airway epithelial cell proliferation, and airway inflammation.	16931638
Tracheitis, Infant, Premature	Altered Intercellular Communication	A combination of prematurity, prolonged endotracheal mechanical ventilation and tracheal infection seem to be responsible for tracheal inflammation and stenosis.	16932914
Intestinal metaplasia, Inflammation, Gastritis, Gastritis, Atrophic	Altered Intercellular Communication	Antral and corpus specimens were obtained to assess the grade of inflammation, topography of gastritis, gastric atrophy, and intestinal metaplasia by histological examination.	16932999
Angioedema, Urticarial vasculitis, Arthralgia, Inflammatory abnormality of the eye, Glomerulonephritis, Lung Diseases, Obstructive, Systemic Vasculitis	Altered Intercellular Communication	Hypocomplementaemic urticarial vasculitis syndrome (HUVS) is a rare disorder characterised by complement activation and the presence of C1q precipitins together with a syndrome of urticarial vasculitis, angioedema, arthralgia, ocular inflammation, glomerulonephritis and obstructive lung disease.	16933473
Supraglottic stenosis, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Initial diagnostic laryngoscopy and biopsies revealed isolated supraglottic stenosis due to fibrosis with acute and chronic inflammation.	16935185
Corneal edema	Altered Intercellular Communication	Most patients presented with corneal edema and anterior segment inflammation.	16935342
Asthma, Respiratory Hypersensitivity, Impaired	Altered Intercellular Communication	The chronic course of asthma characterised by airway hyper-responsiveness and impairment of lung function at school age is determined by continuing allergic airway inflammation beginning in the first 3 years of life.	16935687
Cat-Scratch Disease, Necrosis	Altered Intercellular Communication	Histopathologic examination of a biopsy specimen of the spleen showed necrotizing granulomatous inflammation with central necrosis surrounded by epithelioid cells and occasional Langhans' giant cells, strongly suggestive of Bartonella henselae infection.	16935770
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Diabetes, inflammation, and functional decline in older adults: findings from the Health, Aging and Body Composition (ABC) study.	16936150
Inflammation	Altered Intercellular Communication	Interventions at early stages to reduce inflammation may preserve function in these individuals.	16936150
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The histological degree of fibrosis and inflammation activity was assessed according to the Metavir system.	16937477
Migraine Disorders, Inflammation	Altered Intercellular Communication	We propose that histamine plays a key role in triggering migraines by means of vasodilation and inflammation in the pathogenesis of migraine headaches.	16937756
Inflammation, Aortic Valve Stenosis, atherosclerotic	Altered Intercellular Communication	Biological features (inflammation and neoangiogenesis) and atherosclerotic risk factors in carotid plaques and calcified aortic valve stenosis: two different sites of the same disease?	16938654
Inflammation, Atherosclerosis	Altered Intercellular Communication	Neoangiogenesis and inflammation have a pivotal role in atherosclerosis.	16938654
Inflammation, Dental Plaque, Aortic Valve Stenosis	Altered Intercellular Communication	Inflammation and neoangiogenesis have a crucial role in plaque evolution and in the progression of aortic valve stenosis.	16938654
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	To determine whether the expression of collagenase-3 (MMP-13) in biopsies from patients with inflammatory bowel disease is correlated with histological inflammation parameters.	16938718
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	A positive and significant correlation was found between MMP-13 expression and the histological inflammation scores in mucosal samples from patients with CD (r = 0.74, p < 0.0001) or UC (r = 0.62, p < 0.0001).	16938718
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, acute diverticulitis	Altered Intercellular Communication	Our findings demonstrating the absence of MMP-13 expression in non-inflamed colonic mucosa or in acute diverticulitis, as well as a positive correlation between elevated MMP-13 expression and histological criteria of inflammation in patients with inflammatory bowel diseases (CD and UC) suggest a role of the protease in the pathogenesis of these latter processes.	16938718
Inflammation, Necrosis	Altered Intercellular Communication	Histomorphometric analysis showed rapid incorporation of the allograft at 6 months without inflammation or necrosis.	16939013
Inflammation, Necrosis, Fibrosis Assessment, Saint Lucia, Liver Cirrhosis	Altered Intercellular Communication	Although both chronic active hepatitis-B (CAH-B) and liver cirrhosis (LC) are characterised by various degrees of inflammation and hepatocyte necrosis, in advanced stage cirrhosis, marked fibrosis develops and inflammation and tissue necrosis diminishes.	16939549
Inflammation, Liver damage, Liver Cirrhosis	Altered Intercellular Communication	Additionally, marked reduction of TNF-alpha concentration in advanced cirrhosis suggested that TNF-alpha production is determined by hepatic damage and inflammation.	16939549
Inflammation, Destruction of tissue	Altered Intercellular Communication	This leads to increased inflammation, cytokine expression, and ultimately results in impaired wound healing and tissue destruction.	16939569
Inflammation, Cutaneous Small Vessel Vasculitis, atherosclerotic	Altered Intercellular Communication	Although changes in smaller vessels is the hallmark of medium-sized and small-vessel vasculitis, it has been suggested that large arteries of such patients may also be affected by the early atherosclerotic process because of coexisting risk factors or systemic inflammation.	16940394
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	Cardiovascular risk factors and inflammation (C reactive protein (CRP)) were concomitantly measured in all participants, and diagnosis of high-risk status was defined by the presence of known history of cardiovascular disease, type 2 diabetes or 10-year-Framingham Risk Score > or =20%.	16940394
Inflammation, Vasculitis, CTCAE, Atherosclerosis	Altered Intercellular Communication	Small-vessel vasculitis is associated with more frequent subclinical atherosclerosis, especially extended to multiple peripheral vessels, and such association is not entirely explained by cardiovascular risk factors and systemic inflammation.	16940394
Inflammation	Altered Intercellular Communication	Cerebrospinal fluid inflammation was greater in adults than in children (P = 0.02).	16940837
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Although few inflammatory cells were detected in the mesangial area, paraglomerular inflammation and fibrosis was common.	16941028
Inflammation	Altered Intercellular Communication	Higher contrast-enhancement scores and inflammation were noted in the hand flexor than in the extensor tendons.	16941192
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Endoscopic gastric, duodenal and jejunal biopsies showed chronic inflammation, but vasculitis and immune complex deposition findings were not present.	16941261
Inflammation, Periodontal Diseases, Atherosclerosis	Altered Intercellular Communication	Recent studies have suggested that the periodontal disease, chronic sub-clinical inflammation, is associated with atherosclerosis, although "cause or effect" relationship is still unclear.	16941280
Inflammation, Vascular Diseases	Altered Intercellular Communication	SkC is independent from serum lipids, traditional cardiovascular risk factors, two sensitive markers of systemic inflammation as well as the history of cardiovascular events indicating that the perception of this parameter as an established marker of vascular disease is premature.	16941405
Inflammation, Damage	Altered Intercellular Communication	The data indicate that drug-specific T cells are activated locally and orchestrate a local inflammation via secretion of various cytokines, the type of which depends on the cytokine pattern secreted and which probably is responsible for the renal damage.	16943303
Inflammation, Narcolepsy	Altered Intercellular Communication	A moderate but selective increase in C-reactive protein in hypocretin-1 deficient subjects should prompt research on inflammation in narcolepsy.	16944669
Inflammation, Data types - Address	Altered Intercellular Communication	Accumulating evidence suggests that there is a chronic inflammatory reaction in the areas of the brain affected by AD and C-reactive protein (CRP) is identified as a key molecule of acute phase of inflammation.	16945213
Inflammation	Altered Intercellular Communication	Activation of p38 MAPK is a key signaling step in chronic inflammation.	16947383
Inflammation	Altered Intercellular Communication	These data show that the alpha and gamma isoforms of p38 MAPK dominate in chronic inflammation.	16947383
Inflammation, Restenosis	Altered Intercellular Communication	Insulin resistance or inflammation is known to be related with lipoprotein lipase activity and these factors are also closely associated with the pathogenesis of bare-metal stent restenosis.	16948449
Edema, Cytopathogenic Effect, Viral, Acute Kidney Tubular Necrosis, Interstitial inflammation	Altered Intercellular Communication	A renal biopsy showed acute tubular cell injury including patchy tubular cell necrosis, tubular cell degeneration, and marked proliferation of tubular cells, together with mild interstitial edema and interstitial inflammation, but without significant glomerular or vascular changes.	16948524
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Abdominal aortic aneurysm (AAA) size and growth has been found to be associated with local generation of inflammation markers such as interleukin-6.	16950412
Inflammation	Altered Intercellular Communication	Inflammation also seems to be important in perioperative adverse cardiac events.	16950412
Inflammation	Altered Intercellular Communication	These results suggest an important role for nuclear medicine in the management of patients with infection/inflammation.	16950708
hearing impairment, Inflammation	Altered Intercellular Communication	Our study is the first to show T cell responsiveness to an inner ear-specific protein in ASNHL patients, and implicates cochlin as a prominent target Ag for mediating autoimmune inner ear inflammation and hearing loss.	16951386
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Our findings support a role of inflammation in the etiology of diabetes in the high risk population of Aboriginal Australians.	16952410
Erectile dysfunction	Altered Intercellular Communication	These data suggest that the well established association between erectile dysfunction and pre-diabetes/diabetes (particularly in obese pre-diabetic/diabetic patients) may involve a hormonal component.	16952672
Inflammation, Heart failure	Altered Intercellular Communication	Evidence is accumulating that inflammation plays a role in the pathophysiology of heart failure.	16952920
Refractory anemias, Inflammation, Aortic Stiffness	Altered Intercellular Communication	In the present study, our aim was to establish whether aortic stiffness is increased in RA and to investigate the relationship between inflammation and aortic stiffness.	16952987
Refractory anemias, Inflammation, Aortic Stiffness	Altered Intercellular Communication	RA is associated with increased aortic stiffness, which correlates with current but not historical measures of inflammation, suggesting that increased aortic stiffness may be reversible.	16952987
Refractory anemias, Inflammation	Altered Intercellular Communication	Therefore, effective control of inflammation may be of benefit in reducing cardiovascular risk in patients with RA.	16952987
Inflammation, Swelling	Altered Intercellular Communication	In parallel studies, footpad inflammation was induced in NK1 receptor knock-out (KO) and wild-type (WT) mice, and swelling and NO metabolite levels were measured.	16955242
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	SP, like TNF-alpha and IL-1beta, induces NO in both rheumatoid synoviocytes and experimental models of inflammation.	16955242
Delirium, "Alzheimers Disease	Altered Intercellular Communication	Abnormal neurotransmitter metabolite levels in Alzheimer patients with a delirium.	16955437
Inflammation, Nasal Polyps	Altered Intercellular Communication	Pattern of inflammation and impact of Staphylococcus aureus enterotoxins in nasal polyps from southern China.	16955777
Inflammation, Nasal Polyps	Altered Intercellular Communication	Nasal polyps from China are characterized by B- and T-cell activation, a minor eosinophilic inflammation compared with polyps from white subjects, and a decrease in TGF-beta1 in comparison with control inferior turbinate tissue.	16955777
Refractory anemias, Inflammation, Rheumatoid Arthritis, Atherosclerosis	Altered Intercellular Communication	Chronic systemic inflammation plays a pivotal role in the development of atherosclerosis in rheumatoid arthritis (RA).	16956426
Inflammation, Panniculitis, Avascular necrosis of bone	Altered Intercellular Communication	The term lipomembranous panniculitis refers to a chronic inflammation of the subcutaneous cell tissue, probably representing a non-specific type of ischemic necrosis of the fatty tissue, common to several complaints.	16956517
Lymphoma, Non-Hodgkin, Inflammation, RTEL1 gene	Altered Intercellular Communication	The risk of non-Hodgkin's lymphoma (NHL) has been associated with inflammation.	16956821
Inflammation, RTEL1 gene	Altered Intercellular Communication	Genetic variation in the genes coding for these enzymes (SOD2, GPX1, and CAT, respectively) alters ROS production and therefore may provide a mechanism for the relationship between inflammation and NHL.	16956821
Inflammation, Lymphoma	Altered Intercellular Communication	The risk modification is seen predominantly for marginal zone lymphomas which frequently arise in the context of chronic inflammation.	16956821
Kidney Failure, Chronic, Inflammation, Cardiovascular system	Altered Intercellular Communication	Low free plasma triiodothyronine (fT3) is associated with inflammation and cardiovascular damage in patients with end-stage renal disease (ESRD).	16957565
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Low fT3 may be an intermediate mechanism implicated in the adverse cardiac effects of inflammation in patients with ESRD.	16957565
Pain Distress Question, Inflammation	Altered Intercellular Communication	Clinical symptoms were exposed bone, pain and local inflammation of the mucosa.	16957978
Inflammation, Observation Method - Coagulation, "Alzheimers Disease	Altered Intercellular Communication	We hypothesized that, compatible with premature frailty, chronic stress and age are related in predicting inflammation and coagulation activity in Alzheimer caregivers.	16960028
Inflammation, Dental Plaque	Altered Intercellular Communication	Although lipoprotein-associated phospholipase A2 (Lp-PLA2) has received recent attention as a biomarker of inflammation and risk for acute coronary events, its relative expression in coronary plaque phenotypes, including unstable lesions, has not been established.	16960105
Inflammation, Obesity	Altered Intercellular Communication	In adults, obesity is characterized by a state of chronic low-grade inflammation accompanied by moderately high concentrations of acute phase inflammatory proteins.	16960163
Inflammation	Altered Intercellular Communication	Total body fat seems to be associated with a chronic low-grade systemic inflammation in apparently healthy adolescents.	16960163
ARCN1 gene, Inflammation, Muscular Atrophy, physiopathological	Altered Intercellular Communication	Increasing evidence associates systemic inflammation and oxidative stress with muscle wasting and muscle dysfunction in COPD.	16960513
ARCN1 gene, Inflammation	Altered Intercellular Communication	Low-grade systemic inflammation was significantly (P < 0.05) elevated in all COPD patients and tended to be highest in muscle-wasted patients.	16960513
Presenile dementia, Inflammation, Cerebrovascular Disorders	Altered Intercellular Communication	Inflammation has been involved in the development of dementia in cerebrovascular diseases.	16961066
hyperthermia treatment, Brain Injuries, Inflammation Mediators, Ischemic stroke	Altered Intercellular Communication	Hyperthermia is a surrogate marker of inflammation-mediated cause of brain damage in acute ischaemic stroke.	16961671
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Plasma high-sensitivity CRP (hsCRP) is a marker of inflammation, and it is reported to link with coronary artery disease (CAD).	16963013
Inflammation	Altered Intercellular Communication	We hypothesised that the chronic inflammation in stable CAD mediates priming of neutrophils that impacts the out-come of neutrophil action at an inflammatory site.	16963051
Inflammation	Altered Intercellular Communication	The follow-up was complicated by chronic inflammation of the left mandibular body as a sequel of radiotherapy; it resulted with partial bone destruction, and soft tissue dehiscence.	16963268
Inflammation, Dermatitis	Altered Intercellular Communication	This inducible model of cutaneous inflammation was used to define mediators of skin inflammation that may have clinical relevance.	16964312
Inflammation	Altered Intercellular Communication	Inhibiting PKCalpha also reduced the basal and TNF-alpha- or TPA-induced expression of CXCL8 in cultured psoriatic keratinocytes, suggesting that PKCalpha activity may contribute to psoriatic inflammation.	16964312
Inflammation	Altered Intercellular Communication	Our data suggest that the intrinsic chemoresistance in serous EOC cells may be attributed to the combined action of different molecular mechanisms and factors linked with drug influx and efflux and cell proliferation, as possible implications of other molecular events including altered metabolism, apoptosis and inflammation cannot be excluded.	16964388
Inflammation	Altered Intercellular Communication	This was evident even in patients with a minimal lesion but was most marked in patients with severe damage, mirroring the degree of inflammation in the small intestinal tissue.	16964549
Granulomatous inflammation	Altered Intercellular Communication	Histology confirmed the presence of a dematiaceous fungus, with associated granulomatous inflammation.	16966173
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Inflammation in carotid atherosclerotic plaque: a dynamic contrast-enhanced MR imaging study.	16966482
Orbital Pseudotumor	Altered Intercellular Communication	To perform a multicenter review of the clinical features and treatment of 31 patients with idiopathic sclerosing orbital inflammation.	16966618
Orbital Pseudotumor	Altered Intercellular Communication	We included all patients with histologically confirmed idiopathic sclerosing orbital inflammation from 5 regional orbital centers.	16966618
Orbital Pseudotumor	Altered Intercellular Communication	Idiopathic sclerosing orbital inflammation is a rare condition that can be difficult to diagnose and manage.	16966618
Disorder of the optic nerve, Orbital Pseudotumor	Altered Intercellular Communication	Treatment with an antihelminthic and systemic corticosteroids led to resolution of orbital inflammation but left a persistent optic neuropathy marked by nerve fiber bundle visual field loss with normal visual acuity.	16966936
Inflammation	Altered Intercellular Communication	Increased production of intracellular HO-1 in response to serum factors may play a role in monocyte deactivation after systemic inflammation.	16966997
Ischemia, Postoperative Period, Inflammation, Traumatic injury	Altered Intercellular Communication	It is speculated that, off-pump coronary artery bypass grafting (OPCAB) and also minimally invasive cardiac surgery reduces the incidence of postoperative AF due to reduced trauma, ischemia, and inflammation.	16967324
Inflammation	Altered Intercellular Communication	This translocation might be increased by inflammation of the gut mucosa.	16967390
Gastrointestinal inflammation	Altered Intercellular Communication	Calprotectin is a cytoplasmatic protein of neutrophilic granulocytes and is an established marker for the assessment of localized intestinal inflammation.	16967390
Gastrointestinal inflammation, Liver Cirrhosis	Altered Intercellular Communication	Patients with liver cirrhosis display elevated fecal calprotectin concentrations as a potential sign of intestinal inflammation.	16967390
Alzheimers Disease", Psychotic symptom, Data types - Address	Altered Intercellular Communication	Although the aetiology of psychotic symptoms in Alzheimer's disease (AD) is multi-factorial, alterations in serotonergic neurotransmission are often implicated.	16967466
Inflammation, No immunologic abnormalities	Altered Intercellular Communication	Blood tests showed inflammation but no hematologic or immunologic abnormalities.	16967496
Inflammation	Altered Intercellular Communication	Histologic examination showed chronic inflammation of the striated muscle.	16968242
Inflammation, Cardiovascular calcification	Altered Intercellular Communication	Serum fetuin-A levels link inflammation and cardiovascular calcification in hemodialysis patients.	16968979
HD Term Type, Inflammation	Altered Intercellular Communication	Reduced fetuin-A levels associate with inflammation and increased cardiovascular (CV) mortality in HD.	16968979
HD Term Type, Inflammation	Altered Intercellular Communication	Chronic inflammation in HD patients leads to lower serum fetuin-A levels.	16968979
Inflammation, Hamartoma	Altered Intercellular Communication	SPECT was true negative in 24/27 benign lesions (specificity: 88.9%) and false positive in 2 hamartomas and in 1 aspecific inflammation (range size: 0.8-2 cm), each with a T/N value	16969491
Inflammation, atherosclerotic	Altered Intercellular Communication	These findings suggest that new atherosclerotic progression occurred inside the implanted stent without peristrut inflammation.	16969849
Nephritis, Interstitial, Tubulointerstitial nephritis and uveitis, Uveitis	Altered Intercellular Communication	TINU or Dobrin syndrome is a rare oculo-renal inflammatory condition which is comprised of acute idiopathic tubulointerstitial nephritis and uveitis.	16970260
Inflammation, Secondary malignant neoplasm of chest wall, Communicable Diseases, Lipoma, Malignant Neoplasms	Altered Intercellular Communication	Lipoma, chest wall metastasis, direct invasion from nearby malignancy, infection, and inflammation of chest wall were excluded.	16970274
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Neutrophilic airway inflammation is a prominent feature of chronic obstructive pulmonary disease (COPD) and correlates with disease severity.	16971404
PROS1 gene, Arthritis, Psoriatic, Psoriasis, Polyarthritis	Altered Intercellular Communication	Psoriatic arthritis (PsA) is a systemic inflammatory condition featuring polyarthritis associated with psoriasis.	16971957
Inflammation	Altered Intercellular Communication	Abcesses and inflammation were improved by administration of the antibiotics selected according to the result of fluid culture.	16972615
Inflammation	Altered Intercellular Communication	A granulated lesion accompained by severe inflammation was seen in a biopsied specimen taken from the same site.	16972655
Inflammation, Humor, Uveitis	Altered Intercellular Communication	Our observations suggest that aqueous humor levels of PEDF may be increased as a countersystem against inflammation in uveitis.	16973658
Inflammation, Infiltrate of cornea	Altered Intercellular Communication	Cornea pseudoguttata is commonly found in cases with corneal infiltration and inflammation.	16973660
Inflammation, Atherosclerosis	Altered Intercellular Communication	Subclinical inflammation as quantified by blood levels of C-reactive protein (CRP) contributes to the development and progression of atherosclerosis.	16973973
Inflammation, Aortitis Syndrome	Altered Intercellular Communication	Surgical treatments of aortic root involvement in aortitis syndrome are frequently complicated by valve detachment and pseudoaneurysmal formation during active inflammation.	16977303
Inflammation, Aortic Valve Insufficiency, Coronary ostium stenosis, Aortic Aneurysm, Aortitis Syndrome	Altered Intercellular Communication	A 40-year-old woman with aortitis syndrome complicating the ascending aortic aneurysm, severe aortic regurgitation (AR), and left coronary ostial stenosis was successfully treated by aortic root replacement and concomitant coronary artery bypass grafting (CABG) during acute inflammation.	16977303
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Recent reports have proven the importance of genetic factors and inflammation in the pathogenesis of rheumatoid arthritis (RA).	16977346
Inflammation, Parasitic Diseases	Altered Intercellular Communication	Histology showed inflammation, possibly caused by a fungal or parasitic infection, without definite identification of an organism.	16978407
Inflammation, Helicobacter pylori	Altered Intercellular Communication	Considering the questionable role of Helicobacter pylori as a direct initiator of mutagenesis, the immune disturbances may be caused by the damage of DNA of lymphocytes resulting from the genotoxic effect of some intermediates of inflammation.	16980744
Inflammation, Dysplasia, Infection caused by Helicobacter pylori, Gland, Intestinal metaplasia	Altered Intercellular Communication	To monitor inflammation of gastric mucosa, degree of glandular atrophy (GA), intestinal metaplasia (IM) and dysplasia, and H pylori infection, all patients underwent gastroscopy and biopsy with pathological examination before and after treatment.	16981274
Appendicitis, CTCAE	Altered Intercellular Communication	Stump appendicitis is an acute inflammation of the residual appendix and one of the rare complications after appendectomy.	16981278
Degenerative polyarthritis	Altered Intercellular Communication	The immunohistochemical and histologic analysis was performed in human synovial tissue obtained from 10 patients with post-traumatic inflammation, 14 patients with idiopatic osteoarthritis and normal synovial specimens were obtained from 7 patients undergoing surgery for reconstruction of the anterior cruciate ligament.	16981400
Inflammation	Altered Intercellular Communication	Immunohistochemical data showed iNOS was strongly expressed in the synovial lining layer, subsynovium and blood vessels from patients with acute and chronic inflammation pathology, on the contrary, normal joints were negative.	16981400
Hepatic inflammation, Granulomatous hepatitis, Granulomatous	Altered Intercellular Communication	The etiology of granulomatous hepatitis is extremely extensive for which the granulomatous reaction induced hepatic inflammation is characteristic.	16981420
Inflammation, Granulomatous, Intrahepatic bile duct, Liver Cirrhosis	Altered Intercellular Communication	The histology showed granulomatous reaction, inflammation, intrahepatic bile duct proliferation and micronodular cirrhosis in the liver tissue.	16981420
Inflammation, Neoplasms, Autoimmune Diseases, Communicable Diseases, Disease	Altered Intercellular Communication	A major challenge in daily clinical practice is to differentiate between diseases associated with systemic inflammation, such as neoplasia, infection and autoimmune disease.	16981976
Inflammation, Cachexia	Altered Intercellular Communication	The reverse epidemiology of plasma total homocysteine as a mortality risk factor is related to the impact of wasting and inflammation.	16982634
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	The link between wasting inflammation and a low tHcy appears to be responsible for the reverse association between plasma tHcy and clinical outcome in ESRD patients.	16982634
Cessation of life, Inflammation	Altered Intercellular Communication	After adjustment for confounders including nutritional and inflammation markers, a trend towards increased death risk for high, rather than low, tHcy levels was apparent after adjustment.	16982634
Neurogenic Inflammation, Chronic gastritis	Altered Intercellular Communication	In conclusion, the increased number of SP, NPY, and VIP IR nerves and IR immunocytes suggests that they participate in development of neurogenic inflammation, repairing processes of chronic gastritis.	16983504
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	Infectious agents, inflammation, and growth factors: how do they interact in the progression or stabilization of mild human atherosclerotic lesions?	16983590
Inflammation, Atherosclerotic lesion, Infectious agent	Altered Intercellular Communication	Advanced complicated atherosclerotic lesions have been related to many factors, including inflammation, infectious agents, and growth factors.	16983590
Inflammation, Hyperplastic Polyp, Chlamydia, Atherosclerotic lesion	Altered Intercellular Communication	Mycoplasma pneumoniae (MP) and Chlamydia pneumoniae (CP), inflammation, and growth factors have been associated with severe atherosclerotic lesions in necropsy material in recent work at our lab.	16983590
Inflammation, Hyperplastic Polyp, Atherosclerotic lesion, Atherosclerosis	Altered Intercellular Communication	MP and CP, inflammation, and growth factors, which were already described in severe atherosclerotic lesions in necropsy material, are also present in mild lesions in living patients, strongly favoring a pathogenetic role for these bacteria in the pathogenesis of atherosclerosis.	16983590
Inflammation, Calciphylaxis	Altered Intercellular Communication	Association between calciphylaxis and inflammation in two patients on chronic dialysis.	16983964
Inflammation, Calciphylaxis, Calcinosis, Depression, CTCAE	Altered Intercellular Communication	Inflammation may assist in the development of calciphylaxis through depression of serum levels of fetuin-A, an endogenous inhibitor of calcification that is also a negative acute-phase reactant.	16983964
Hyperparathyroidism, Calciphylaxis	Altered Intercellular Communication	Here, we present two patients who had chronic inflammatory conditions and hyperparathyroidism and who developed calciphylaxis.	16983964
Inflammation, Neoplasms	Altered Intercellular Communication	The MRI findings resembled either invasive brain tumor or local inflammation.	16984029
Inflammation, Neoplasms	Altered Intercellular Communication	Inflammatory myofibroblastic tumor (IMT) is clinically and histologically characterized by inflammation.	16984614
Inflammation, Cardiovascular Diseases, Refractory anemias, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Rheumatoid Arthritis	Altered Intercellular Communication	Rheumatoid arthritis (RA) is characterized by inflammation and an increased risk for cardiovascular disease (CVD).	16984661
Inflammation, Atherosclerosis	Altered Intercellular Communication	We hypothesize that DMARD use, in particular MTX use, results in powerful suppression of inflammation, thereby reducing the development of atherosclerosis and subsequently clinically overt CVD.	16984661
Stiff-Person Syndrome, Autoimmune Diseases of the Nervous System, SMS gene	Altered Intercellular Communication	Stiff-person syndrome (SPS) is an autoimmune neurological disorder characterized by autoantibodies to glutamic acid decarboxylase (GAD), the enzyme responsible for the synthesis of inhibitory neurotransmitter GABA.	16984900
Inflammation, Carcinogenesis, Carcinoma of lung	Altered Intercellular Communication	Chronic inflammation contributes to the process of carcinogenesis, but few epidemiologic studies have examined associations with risk of lung cancer.	16985037
Inflammation, Carcinoma of lung	Altered Intercellular Communication	High levels of serum Hsp70 might thus be associated with increased risk of lung cancer among Japanese males, although further studies are needed to clarify associations between chronic inflammation and lung cancer.	16985037
Inflammation, Malnutrition	Altered Intercellular Communication	Among non-traditional cardiovascular risk factors both malnutrition and inflammation appear to be strong predictors of mortality and morbidity in haemodialysis (HD) patients.	16985487
Granulomatous inflammation, histiocytic	Altered Intercellular Communication	In selected cases, histiocytic markers (CD-68 and HAM-56) were used to identify the presence of epithelioid histiocytes, which characterises a granulomatous inflammation.	16987903
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	A leading hypothesis for the role of bacteria in inflammatory bowel diseases is that an imbalance in normal gut flora is a prerequisite for inflammation.	16988016
Crohn Disease, Inflammation	Altered Intercellular Communication	Imbalance in flora in Crohn's disease is probably not sufficient to cause inflammation, since microbiotas from inflamed and noninflamed tissues were of similar compositions within the same individual.	16988016
Inflammation, Venous Thromboembolism, Metabolic Syndrome X, Impaired health, Overweight	Altered Intercellular Communication	A metabolic syndrome independent association between overweight, fibrinolysis impairment and low-grade inflammation in young women with venous thromboembolism.	16988550
Neoplasms	Altered Intercellular Communication	The appendix can also be the site of a variety of neoplasms and unusual inflammatory conditions.	16988762
Inflammation, Granulomatosis with polyangiitis, Vasculitis, CTCAE	Altered Intercellular Communication	The pathomorphological diagnostic criteria is known as Wegener's triad: 1) necrotizing granlomatous inflammation of upper and/or lower respiratory tract, 2) systemic or focal necrotizing vasculitis involving arteries and vein, and 3) focal segmental necrotizing crescentic gromerulonephritis.	16989448
vascular inflammations	Altered Intercellular Communication	The rise in ANCA level during vascular inflammation is very important for monitoring disease.	16989448
Sclerosis, Inflammation, Granuloma, Foreign-Body	Altered Intercellular Communication	They were examined, focusing on the following parameters: acute and chronic inflammation, fibrosclerosis, and foreign body granulomatous reaction.	16989698
Inflammation	Altered Intercellular Communication	Histological assessment showed the presence of acute and chronic inflammation, generally of mild and medium grade; fibrosclerosis was present mostly in a severe form, indicating a biological periprosthesic wall that separates and protects the gastric wall from the band; no cases of foreign body reaction were observed, nor were silicone inclusions found inside the inflammatory cells.	16989698
Inflammation, Thrombus, Atherosclerosis	Altered Intercellular Communication	Several markers of inflammation predict the risk of thrombotic cardiovascular events in patients with atherosclerosis.	16989837
vascular inflammations	Altered Intercellular Communication	However, the mechanism by which vascular inflammation promotes atherothrombotic disease is incompletely understood.	16989837
Inflammation, Ischemic stroke	Altered Intercellular Communication	High von Willebrand factor levels increase the risk of first ischemic stroke: influence of ADAMTS13, inflammation, and genetic variability.	16990571
Hepatitis	Altered Intercellular Communication	The percentage of intrahepatic CD45RO+ and CD28+ T cells correlated with the degree of liver inflammation, which suggests that memory T cells at relatively early stages of differentiation are directly involved in liver inflammation.	16991081
Inflammation, Kidney Failure, Acute, SLC25A10 gene	Altered Intercellular Communication	The above treatment produced regression of systemic inflammation, DIC and acute renal failure.	16995345
Communicable Diseases, Primary malignant neoplasm, Stomach Carcinoma, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Helicobacter pylori (Hp) infection is frequently observed in the remnant stomach after gastric cancer surgery, and is considered to play one of the important roles in chronic mucosal inflammation and cancer development.	16995475
Communicable Diseases, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The correlation between PG levels and the grade of mucosal inflammation in the remnant stomach was investigated together with the status of Hp infection.	16995475
Inflammation, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Significantly higher serum PG II level and lower PG I/II ratio were found in cases with histologically severe mucosal inflammation than in those without inflammation.	16995475
Communicable Diseases, Stomach Carcinoma, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Hp infection and active mucosal inflammation, but not bile reflux or mucosal atrophy, significantly affect on the serum PG level in patients with remnant stomach after gastric cancer surgery.	16995475
Inflammation	Altered Intercellular Communication	Serum PG level was suggested to indicate the grade of acute and chronic Hp-related inflammation in those patients.	16995475
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Evaluation of proinflammatory cytokines and inflammation markers as biomarkers for the action of thiazolidinediones in Type 2 diabetes mellitus patients and healthy volunteers.	16995860
Inflammation, Erythema, Burn injury, Pain Distress Question	Altered Intercellular Communication	The use of a biphasic waveform for DC cardioversion reduces the inflammation and pain of burns as measured by erythema index and visual analogue scale.	16996194
Esophagitis, Eosinophilic inflammation	Altered Intercellular Communication	To characterize a pediatric population with AEE to determine if AEE can be diagnosed based on history; to compare patients with varying degrees of esophageal eosinophilic inflammation to determine if moderate esophageal inflammation is part of a continuum of AEE.	16996334
Esophagitis	Altered Intercellular Communication	History and clinical presentation were not useful in predicting the severity of histologic esophageal inflammation in this cohort.	16996334
Inflammation, Malignant Neoplasms, Failure (biologic function)	Altered Intercellular Communication	Causes for failure included difficult anatomy (55.9%), inadequate preparation (20.8%), obstructing malignancy (8.6%), discomfort (8.1%), and severe inflammation (6.1%).	16996349
Dysplasia, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Among confounding factors are interobserver variability, tangential sectioning, and severe mucosal inflammation leading to architectural and cytologic atypia similar to that of dysplasia.	16996568
Infarction, Inflammation, Thrombosis	Altered Intercellular Communication	Histopathology, not previously described, showed inflammation to spread preferentially along eyelid fibrofatty-fascial tissue planes into the orbit and along orbital fibrous septae, leading to intense perivascular inflammation, thrombosis, and ocular infarction.	16996594
Inflammatory abnormality of the eye	Altered Intercellular Communication	Differential effectiveness of etanercept and infliximab in the treatment of ocular inflammation.	16996615
Inflammatory abnormality of the eye	Altered Intercellular Communication	We reviewed our patients on etanercept and infliximab to determine whether these medications are equally efficacious in controlling ocular inflammation.	16996615
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Few data are currently available investigating neurosteroids (NS) in Alzheimer's disease (AD).	16997284
Data types - Address	Altered Intercellular Communication	Neurosteroids may have utility as candidate biomarkers in AD.	16997284
Alzheimers Disease	Altered Intercellular Communication	The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease.	16997284
Pleurisy	Altered Intercellular Communication	Progelatinase B/proMMP-9 has recently been identified as an indicator of pleural inflammation, presumably originating from granulocytes.	17000556
Inflammation, Chlamydia, Atherosclerosis, Coronary Stenosis	Altered Intercellular Communication	Interaction between Chlamydia pneumoniae seropositivity, inflammation and risk factors for atherosclerosis in patients with severe coronary stenosis.	17000560
Inflammation, Chlamydia, Coronary Arteriosclerosis, Coronary Artery Disease	Altered Intercellular Communication	To investigate whether Chlamydia pneumoniae (Cpn) seropositivity in patients with suspected coronary artery disease (CAD) (n = 81) is associated with increases in markers of inflammation, the severity of coronary atherosclerosis, and traditional risk factors for cardiovascular events.	17000560
Communicable Diseases, Inflammation	Altered Intercellular Communication	Inflammation was evident at semen analysis, but no infection was detected by microbiological examination and sperm culture.	17000649
Ductal Breast Carcinoma	Altered Intercellular Communication	The prevalence of TR was significantly increased in the ductal adenocarcinomas compared with that in the stroma of nonneoplastic inflammation (P<0.0001).	17000676
Inflammation	Altered Intercellular Communication	The inflammation was in a periductal, perilobular, and perivascular distribution.	17001167
Inflammation, Restenosis	Altered Intercellular Communication	Inflammation and apoptosis genes and the risk of restenosis after percutaneous coronary intervention.	17001294
Inflammation, Restenosis	Altered Intercellular Communication	Genetic factors appear to be important in the development of restenosis after percutaneous coronary intervention, as well as in the process of inflammation, a pivotal factor in restenosis.	17001294
Gingivitis, Dental Plaque	Altered Intercellular Communication	Poorer oral hygiene, increased dental plaque, and increased gingival inflammation progressed from childhood to teenage years.	17001665
Inflammation, Leukopenia	Altered Intercellular Communication	Existing clinical factors, for example, inflammation or leukopenia, may influence whether infused mediators cause reactions.	17002639
Inflammation, diabetic, Hypogonadotropic hypogonadism	Altered Intercellular Communication	We have now hypothesized that type 2 diabetic subjects with hypogonadotrophic hypogonadism may have a lower hematocrit because testosterone stimulates, whereas chronic inflammation suppresses, erythropoiesis.	17003308
Uveomeningoencephalitic Syndrome, hearing impairment, Retinal Detachment, Blindness, Tinnitus, granulomatous uveitis, Optic Neuritis	Altered Intercellular Communication	Patients with VKH often report tinnitus and hearing loss, but these symptoms tend to be given secondary consideration because most undergo treatment with steroids to prevent blindness resulting from granulomatous uveitis, exudative retinal detachment, and optic nerve inflammation.	17003710
Orbital Pseudotumor	Altered Intercellular Communication	Under the impression of nonspecific orbital inflammation, she was treated with oral prednisone with initial response.	17004636
Nerve Degeneration	Altered Intercellular Communication	These findings suggest that loss of orexin neurons or impaired orexin neurotransmission might exist as a part of the neurodegeneration associated with advanced PSP with long duration of morbidity.	17005202
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	These characteristics are strongly associated with diabetes, decreased heart rate variability, and chronic inflammation.	17005327
Inflammation, Hypertension, CTCAE, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	The ramifications of these findings with respect to insulin resistance, sympathetic tone, inflammation and hypertension, often associated with pathologic atrial fibrillation, are discussed.	17005327
Inflammation, Anterior uveitis	Altered Intercellular Communication	One hundred fifty seven British Caucasian patients with anterior uveitis were identified and divided into those where the inflammatory process lasted less than 3 months (RAU=118) and those where the inflammation persisted longer than 3 months (CAU=39).	17005410
Inflammation, RTEL1 gene	Altered Intercellular Communication	Nutrients that affect inflammation, vitamin D activity, oxidative DNA damage, or DNA methylation may be associated with risk of NHL.	17005624
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation plays a key role in ACS, and the anti-inflammatory effects of local elution of dexamethasone in unstable plaques may represent a valid therapeutic approach.	17005712
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Subclinical inflammation is related to adverse events in patients with coronary artery disease.	17006323
Inflammation	Altered Intercellular Communication	Stable long-term CsA-maintained cardiac transplant patients exhibit a significant and general increase in hemostatic parameters and markers for subclinical inflammation.	17006323
Inflammation	Altered Intercellular Communication	Hypertrophic cranial pachymeningitis associated with middle ear inflammation.	17006342
Inflammation	Altered Intercellular Communication	To describe a series of patients with hypertrophic cranial pachymeningitis (HCP) associated with chronic middle ear inflammation.	17006342
Inflammation	Altered Intercellular Communication	Chronic middle ear inflammation might be involved in the pathogenesis of HCP, probably mediated by the venous return.	17006342
Prostate carcinoma, prostatitis	Altered Intercellular Communication	Further studies are needed to clarify its role in contributing to the development of prostatic inflammation and prostate cancer.	17006718
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Inhaled fluticasone and salmeterol suppress eosinophilic airway inflammation in chronic obstructive pulmonary disease: relations with lung function and bronchodilator reversibility.	17006748
Inflammation	Altered Intercellular Communication	Intraobserver agreement was only moderate for lobular inflammation.	17006934
Inflammation, Gastritis	Altered Intercellular Communication	The mean activity, inflammation, and gastritis scores were also higher in the antrum of patients than in the antrum of controls.	17007018
Inflammation	Altered Intercellular Communication	Markers of neurohormonal activation and inflammation play a pivotal role in non-ST-elevation acute coronary syndromes (NSTE-ACS).	17007172
Inflammation	Altered Intercellular Communication	Muscle pathology shows no sign of active inflammation but increased endomysial connective tissue associated with basal lamina duplication and collagen disorganization.	17008331
Noninfiltrating Intraductal Carcinoma, Comedo Necrosis, Inflammation	Altered Intercellular Communication	Forty five of 100 patients with biopsy-proven DCIS who underwent MRI and had sufficient tissue to be characterized by pathologic (nuclear grade, presence of comedo necrosis, size, and density of disease) and immunohistochemical (IHC) findings (proliferation, Ki67; angiogenesis, CD34; and inflammation, CD68).	17008702
Inflammation	Altered Intercellular Communication	The correlation was largely due to size, density (by either MRI or pathology), and inflammation (P < .05).	17008702
Inflammation, Granuloma	Altered Intercellular Communication	Microscopically, superficial granulomatous inflammation with perifollicular caseating granulomas is the hallmark.	17010176
Presenile dementia, Inflammation, Hyperhomocysteinemia	Altered Intercellular Communication	Incidence studies of blood inflammatory markers as predictors of dementia in older age are few and did not take into account hyperhomocysteinemia, although this condition is associated with both inflammation and increased risk of dementia.	17011077
Inflammation, Cornea	Altered Intercellular Communication	A 76-year-old man developed anterior chamber inflammation five months after uncomplicated clear corneal cataract surgery.	17011874
Inflammation	Altered Intercellular Communication	After intraocular surgery, metaplastic epithelial downgrowth may occur as a consequence of occult ocular surface squamous neoplasia and masquerade as chronic inflammation; clinicians should be aware of this rare complication.	17011874
Inflammatory abnormality of the eye	Altered Intercellular Communication	Five occurrences of mild to moderate ocular inflammation were reported.	17011952
Communicable Diseases, Inflammation	Altered Intercellular Communication	An ideal dural substitute that enables watertight closure, has sufficient strength, and can be absorbed without remnant materials that induce inflammation, adhesion, and infection is not available.	17013732
Inflammation, Infection, Malignant Neoplasms	Altered Intercellular Communication	C-reactive protein (CRP) is an acute phase reactant protein, which becomes elevated in response to inflammation, infections or malignancies.	17014552
Inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	We hypothesise that delayed or altered clearance of apoptotic cells after UV irradiation will lead to inflammation in the skin of SLE patients.	17014704
Inflammation, Smooth muscle (tissue)	Altered Intercellular Communication	Activation of the cyclic AMP (cAMP) signaling pathway leads to the suppression of inflammation in the airways and relaxation of airway smooth muscle.	17016624
Epilepsy, Congenital duplication of uterus	Altered Intercellular Communication	We elected to offer this method to a woman with uterus didelphys and a poorly controlled seizure disorder who wished to avoid hormonal and barrier contraceptives.	17018498
Myeloproliferative disease, allergic inflammation, Malignant Neoplasms	Altered Intercellular Communication	Basophils play an important role in allergic inflammation and are pathologically related to hematological disturbances, such as iron deficiency anemia and myeloproliferative disorders; however, they are only rarely encountered in lymphoid malignancies.	17019691
Inflammation	Altered Intercellular Communication	In four cases the disease had clinically the fulminant course and the inflammation was transmural.	17019974
Inflammation, Hyperemia	Altered Intercellular Communication	We found intensive vascularization and hyperemia of the intestinal wall to be the common features accompanying the inflammation.	17019974
Autoimmune Diseases, Autoimmune Chronic Hepatitis, Hepatitis, Insemination, Artificial, Homologous	Altered Intercellular Communication	Autoimmune hepatitis (AIH) is an organ-specific autoimmune disease characterized by chronic inflammation of the liver.	17020818
Inflammation	Altered Intercellular Communication	Latency of alpha-herpes viruses is accompanied by a chronic inflammation in human trigeminal ganglia but not in dorsal root ganglia.	17021407
Inflammation, Vascular Diseases	Altered Intercellular Communication	The role of chronic inflammation causing metabolic and vascular disorders is increasingly recognized.	17021763
palladium, Inflammation, Gingiva	Altered Intercellular Communication	Subgingival irrigation with SAE solution as an adjunct to SRP is effective at reducing gingival inflammation, but not PD, RAL, and the number of A. actinomycetemcomitans and/or P. gingivalis.	17022368
Inflammation, Abdominal Neoplasms	Altered Intercellular Communication	CT of the abdomen revealed thickening of the gallbladder wall and acute local inflammation, as well as the presence of abdominal tumor in the right lower quadrant.	17022900
Inflammation, Cardiac complication, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a pivotal role in the pathogenesis of atherosclerosis and of cardiovascular and cerebrovascular complications.	17023672
Inflammation	Altered Intercellular Communication	Transforming growth factor-beta1 (TGF-beta1) is a pleiotropic cytokine with a central role in inflammation.	17023672
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	In obese children, subclinical inflammation is often present and is correlated with the metabolic syndrome.	17023700
Inflammation, Endothelial dysfunction, diabetic	Altered Intercellular Communication	Coffee consumption and markers of inflammation and endothelial dysfunction in healthy and diabetic women.	17023717
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The objective was to assess the relation between long-term caffeinated and decaffeinated filtered coffee consumption and markers of inflammation and endothelial dysfunction.	17023717
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	In contrast, the results suggest that coffee consumption is inversely associated with markers of inflammation and endothelial dysfunction.	17023717
Inflammation	Altered Intercellular Communication	It was possible to differentiate between inflammation and inconspicuous findings.	17024457
Inflammation	Altered Intercellular Communication	We speculated that the cause was inflammation of the retina and choroid, and accumulation of subretinal fluid for a long period.	17025231
Lichen Planus, Inflammation	Altered Intercellular Communication	Type I interferon-associated cytotoxic inflammation in lichen planus.	17026519
Inflammation	Altered Intercellular Communication	Recent studies suggested that type I interferons (IFNs) play a central role in cytotoxic skin inflammation by increasing the expression of IP10/CXCR10 and recruiting effector cells via CXCR3.	17026519
Inflammation, Malignant Neoplasms, Urinary Tract Fistula	Altered Intercellular Communication	To report our 12-year experience with radiological treatment (ureteric embolization) for refractory urinary fistula, as malignancy, radiation therapy, and/or chronic inflammation increase the risk of lower urinary tract fistula after surgical urinary diversion, which can lead to significant morbidity, and for patients who are not surgical candidates permanent nephrostomy drainage and ureteric embolization offer an alternative form of urinary diversion.	17026590
Inflammation, Urticaria	Altered Intercellular Communication	According to the results of our study, spontaneous urticaria lesions seem to be sustained by a characteristic inflammation pattern where neutrophils, adhesion molecules, IL-8 and chemokine receptors play a main role in flogosis triggering and, consequently, disease development.	17026835
Airway structure	Altered Intercellular Communication	Non-invasive assessment of airway inflammation in ship-engine workers.	17026845
Airway structure	Altered Intercellular Communication	By increasing airway inflammation from oxidative-stress, tobacco smoking appears to interact with other chemical or physical factors elicited during sea navigation.	17026845
Inflammation, Ischemia, Cerebrovascular accident	Altered Intercellular Communication	Several studies have stressed the involvement of inflammation in the pathophysiology of acute brain ischemia, but the role of immunoinflammatory activation in diabetic stroke patients has not yet been fully evaluated.	17026849
Inflammation	Altered Intercellular Communication	After operative repair, the majority of cases presented with a distinct regression of inflammation.	17026911
Inflammation, Primary malignant neoplasm, Malignant neoplasm of ovary	Altered Intercellular Communication	The majority of ovarian cancers are derived from ovarian surface epithelium and the inflammation caused by successive ovulation seems to a play a role in the development of cancer.	17028049
Hepatitis	Altered Intercellular Communication	Activation of Kupffer cells increases free radical release, which may, in turn, enhance cytokine secretion, creating a positive feedback loop, which contributes to liver inflammation.	17028306
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Inflammation is involved in the process of coronary heart disease (CHD).	17029206
Postoperative Complications, Uveitis	Altered Intercellular Communication	Postoperative complications included chronic intraocular inflammation and superior corectopia.	17031292
Data types - Address	Altered Intercellular Communication	Since our data show changes in antioxidants, neurotransmitters and their precursors, or FAA associated with urea metabolism in pAD compared with CT, we propose that manipulation of these metabolic pathways may be important in preventing AD progression.	17031479
Inflammation, Pain Distress Question	Altered Intercellular Communication	To describe MR imaging findings of inflammation of Hoffa's fat pad as a cause of nonspecific knee pain in the HIV-infected population.	17031684
Inflammation	Altered Intercellular Communication	While the MR imaging findings of diffuse inflammation of Hoffa's fat pad are nonspecific and unclear in etiology, an association with HIV may exist.	17031684
Renal Insufficiency, Inflammation	Altered Intercellular Communication	Propofol attenuates free-radical-mediated lipid peroxidation and systemic inflammation in patients with impaired myocardial function undergoing CABG.	17032661
Hyperthyroidism, ovarian neoplasm, Inflammation	Altered Intercellular Communication	Ovarian cancer is hormone-dependent, and epidemiological evidence links hyperthyroidism, inflammation of the ovarian surface, and increased risk of ovarian cancer.	17032711
Hyperthyroidism, ovarian neoplasm, Inflammation	Altered Intercellular Communication	Ovarian cancer is hormone-dependent, and epidemiological evidence links hyperthyroidism, inflammation of the ovarian surface, and increased risk of ovarian cancer.	17032711
Inflammation, Gastritis	Altered Intercellular Communication	There are numerous studies suggesting that inflammation of the oral cavity caused by bacteria or fungi is accompanied by gastric inflammation.	17033108
Inflammation, Nucleolar Fibrillar Material, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Most important finding of our study is that patients with recognized inflammation in the oral cavity in the form of stomatitis prothetica hyperplasica both fibrosa as well as papillaris showed in nearly 100% gastric H. pylori infection, usually without the presence of the same bacterium in the oral cavity, suggesting that gastric H. pylori infection affects oral mucosa at distance by some, as yet, unknown mechanism.	17033108
Inflammation, Lichen Sclerosus et Atrophicus	Altered Intercellular Communication	In the lichen sclerosus specimens the zone of inflammation also demonstrated increased immunostaining for TNF-alpha, IL-1alpha, IFN-gamma receptor, CD25, CD11a and ICAM-1 while the zone of sclerosus demonstrated a smaller increase in immunostaining for IFN-gamma receptor, TNF-alpha, CD11a and ICAM-1, and the epidermis demonstrated increased staining for ICAM-1.	17034521
allergic inflammation	Altered Intercellular Communication	The data indicate that autoantibodies against CD28 could be a new immunological mechanism in allergic inflammation.	17034578
Exophthalmos, Orbital Pseudotumor	Altered Intercellular Communication	Patients with DON may not have severe proptosis and orbital inflammation.	17035276
Airway structure	Altered Intercellular Communication	Sputum induction is a tool to monitor airway inflammation, yet it may induce by itself a neutrophilic response when repeated within 24 to 48 h. This limits its repeated use in clinical trials.	17035451
Inflammation, Disease	Altered Intercellular Communication	There was no difference between the groups with regard to age (55.7 years), American Society of Anesthesiologists score (1.86), previous diseases, and extent of inflammation.	17036202
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Shorter LTL equivalent to around 11 years of annual loss in normal people is associated with radiographic hand osteoarthritis and disease severity, suggesting potential shared mechanisms between osteoarthritis and ageing, and implicating oxidative stress and low-level chronic inflammation in both conditions.	17038452
Allergic, Inflammation, Testicular mass, Atopy	Altered Intercellular Communication	Polyphenols derived from apples have been reported to suppress histamine release from rat cells, reduce auricular swelling in allergic mice, and alleviate skin inflammation in atopic patients.	17039666
Inflammation, Colitis	Altered Intercellular Communication	Microscopic colitis are defined as a chronic inflammation of a normal macroscopic colonic mucosa.	17039729
Cholesteatoma, Inflammation	Altered Intercellular Communication	But even from the same sample, the cholesteatoma from the positions with severe inflammation in the perimatrix count much higher, and the difference was statistically significant.	17039796
Inflammation, Cholesteatoma	Altered Intercellular Communication	The results suggested that it was the severity of inflammation in the perimatrix influenced the differences, but not the origins of the cholesteatoma.	17039796
Granulomatous inflammation, Pneumonia, Interstitial, Neutrophil Infiltration	Altered Intercellular Communication	Histological examination revealed granulomatous inflammation with neutrophil and eosinophil infiltration around the worm and interstitial pneumonia surrounding the nodule.	17040290
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The upregulated resistin at local sites of inflammation and the link between serum resistin, inflammation and disease activity suggest a role for resistin in the pathogenesis of rheumatoid arthritis.	17040961
Inflammation	Altered Intercellular Communication	Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging.	17041012
Inflammation	Altered Intercellular Communication	The silent information regulator 2 (Sir2) family of proteins (sirtuins or SIRTs), which belong to class III histone/protein deacetylases, have been implicated in calorie restriction, aging, and inflammation.	17041012
Inflammation	Altered Intercellular Communication	Thus our data show that SIRT1 regulates cigarette smoke-mediated proinflammatory mediator release via NF-kappaB, implicating a role of SIRT1 in sustained inflammation and aging of the lungs.	17041012
Inflammation, Demyelination, MS gene	Altered Intercellular Communication	The alterations in oligodendrocyte Nfasc155 expression that accompany inflammation and demyelination suggest an ongoing disruption to the axonal-oligodendrocyte complex within newly forming as well as established lesions in multiple sclerosis, resulting in destruction of the Nfasc186+/Na+v nodal complex vital to successful fast neurotransmission in the CNS.	17041241
Inflammation, Demyelination, MS gene	Altered Intercellular Communication	The alterations in oligodendrocyte Nfasc155 expression that accompany inflammation and demyelination suggest an ongoing disruption to the axonal-oligodendrocyte complex within newly forming as well as established lesions in multiple sclerosis, resulting in destruction of the Nfasc186+/Na+v nodal complex vital to successful fast neurotransmission in the CNS.	17041241
Intestinal metaplasia, Gastric Adenocarcinoma, Hyperplasia, Acute and chronic inflammation	Altered Intercellular Communication	Intramucosal gastric adenocarcinomas of poorly differentiated type in the young may be associated with H. pylori infection with antral chronic inflammation with lymphoid-follicle hyperplasia, regardless of the existence of intestinal metaplasia within the background gastric mucosa.	17041565
intraepithelial, Mucinous metaplasia	Altered Intercellular Communication	One false-positive case of mucinous metaplasia (1/3, 33%) showed marked intraepithelial acute inflammation.	17041953
Adenocarcinoma, Inflammation, Pancreatic Intraductal Papillary Mucinous Neoplasm	Altered Intercellular Communication	False-positive diagnosis of adenocarcinoma occurs not infrequently in the setting of IPMN with severe dysplastic epithelial change and in lesions with associated acute inflammation, and can be a pitfall in the diagnosis of these lesions.	17041953
Airway structure, Asthma	Altered Intercellular Communication	Severe asthma represents a heterogeneous group of patients whose characteristics of airway inflammation are poorly known.	17042136
Intestinal metaplasia, Inflammation, Helicobacter pylori, Atrophic	Altered Intercellular Communication	After treatment, a significative fall of Helicobacter pylori and activity and atrophy was established, contrarity to intestinal metaplasia and chronic inflammation witch are persisted.	17042205
TAO brand of troleandomycin, Inflammation, Disorder of eye	Altered Intercellular Communication	The extraocular muscles are one of the primary tissues implicated in the autoimmune-mediated inflammation of thyroid-associated ophthalmopathy (TAO).	17042681
Inflammation, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation and inflammatory biomarkers play an important role in atherosclerosis and cardiovascular disease.	17042946
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Little information is available, however, on time course of serum markers of inflammation after stroke.	17042946
Inflammation, Asthma	Altered Intercellular Communication	In patients with asthma who have a helper T-cell 2-dominant predisposition, a patulous eustachian tube easily allows the entry of antigenic materials into the middle ear, causing eosinophil-dominant inflammation.	17043260
Histiocytosis haematophagic, Inflammation	Altered Intercellular Communication	Furthermore, the association of hemophagocytosis with an increase in HO-1 expression may indicate a novel role for this apparently futile process as a negative regulator of inflammation.	17044836
Inflammation, Hypertension, CTCAE, Atherosclerosis, Diabetes Mellitus	Altered Intercellular Communication	Inflammation may be important for accelerated progression of atherosclerosis in patients with hypertension or diabetes, but few studies included subjects with early stages of atherosclerosis such as those with asymptomatic carotid lesions.	17045118
Inflammation, International Medical Terminology, Hypertension, CTCAE	Altered Intercellular Communication	By multivariate analysis we searched, among all evaluated cardiovascular risk factors including markers of inflammation, for independent variables associated with carotid lesions (IMT >1.5 mm) and found in patients with hypertension a predictive role for elevated levels of CRP (OR 4.1, 95% CI 1.1-16.4, p = 0.0429), whereas in diabetics we found a predictive role for elevated levels of fibrinogen (OR 6.0, 95% CI 2.0-18.1, p = 0.0014) and CRP (OR 4.4, 95% CI 1.4-13.7, p = 0.0096).	17045118
Inflammation, Necrosis	Altered Intercellular Communication	Histologic sections were analyzed for amount of inflammation and necrosis.	17046099
Dacryoadenitis	Altered Intercellular Communication	Microscopic examination revealed periglandular infiltration with chronic inflammation of the palpebral lobe of lacrimal gland.	17048448
Cataract, Inflammation, Glaucoma, CTCAE, Uveitis	Altered Intercellular Communication	With adequate inflammation suppression, phacotrabeculectomy with mitomycin C is an effective and safe therapeutic option for the management of secondary cataract and glaucoma in uveitic eyes.	17049331
Acute inflammation, Uveitis	Altered Intercellular Communication	A lower surgical success rate of the uveitic group might be attributable to the postoperative inflammation recurrence.	17049331
Inflammation	Altered Intercellular Communication	Inflammation also reduces clearance of some drugs or active metabolite, thereby reducing response.	17050800
Inflammation	Altered Intercellular Communication	Despite reduced concentrations of the active metabolite, AT1R antagonists potency does not appear to be reduced by inflammation.	17050800
Rheumatoid Arthritis	Altered Intercellular Communication	Inflammatory conditions, such as rheumatoid arthritis, reduce response to calcium channel and beta-adrenergic antagonists but not the angiotensin II type 1 receptor (AT(1)R) antagonist valsartan.	17050800
Inflammation, "Stensens duct	Altered Intercellular Communication	The authors present two major complications, a rare case of Stensen's duct laceration and a case of chronic inflammation mandating surgical treatment.	17051121
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	With time the inflammation changes and hyalin fibrosis takes place.	17051409
Inflammation, Hepatitis, Necrosis, Hepatitis A, Autoimmune Chronic Hepatitis, Portal inflammation	Altered Intercellular Communication	In addition it was compared to the usual histological characteristics of viral hepatitis, most importantly hepatitis C. The morphological changes examined first were the ones that constitute the diagnostic criteria of autoimmune hepatitis: the severity of portal inflammation and interface hepatitis, the cell composition of the inflammation, rosette formation of periportal hepatocytes, and the presence and extent of centrilobular and bridging necrosis.	17051746
Inflammation	Altered Intercellular Communication	Results indicated that in most cases the portal/periportal inflammation was very active and lead to the destruction of the original liver structure which was followed by regeneration process (periportal rosettes).	17051746
Inflammation	Altered Intercellular Communication	The majority of periapical radiolucent areas were histologically proven to be chronic periapical inflammation.	17052585
Orbital Pseudotumor	Altered Intercellular Communication	Echography, computed tomography scan, and magnetic resonance imaging allowed distinction from other types of orbital inflammation.	17052628
Inflammation	Altered Intercellular Communication	The second component was reflected by a marker of inflammation and was associated with knee ROA, high Western Ontario and McMaster Universities (WOMAC) scores and body mass index (BMI).	17052923
Inflammation	Altered Intercellular Communication	Keloids arise from the aberrant wound healing process and nitric oxide (NO) plays an important role in the inflammation stage of wound healing.	17052928
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Patients with chronic obstructive pulmonary disease (COPD) have an ongoing systemic inflammation, which can be assessed by measuring serum C-reactive protein (CRP).	17053205
Pneumonitis, Data types - Address	Altered Intercellular Communication	This finding may be the result of ongoing pulmonary inflammation as a result of the long half-life of AD.	17053388
Inflammation	Altered Intercellular Communication	Inappropriate activation of hemostasis and inflammation may contribute to postoperative morbidity and mortality.	17056936
Inflammation, Febrile Neutropenia, CTCAE	Altered Intercellular Communication	We hypothesized that cancer-related inflammation might increase the risk of febrile neutropenia (FN) induced by docetaxel (DCX, Taxotere), by both affecting the exposure to DCX and the tissue sensitivity.	17060489
Inflammation, Ear Inflammation	Altered Intercellular Communication	Temporary otitis media with effusion was seen in one ear, mild inflammation around the ligated site also in one ear, but no other serious complication has been observed.	17061083
Intraocular inflammation	Altered Intercellular Communication	During the follow-up, there were no sings of intraocular inflammation or any other intraocular pathology induced by the intravitreal injection.	17061237
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	These findings are consistent with research that suggests relationships between chronic periodontal inflammation and the development of CHD, especially among younger men.	17062738
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	After dividing participants into four groups based on CRP and albumin levels (<5 mg/dl CRP and <3.5 mg/dl albumin), subjects with severe inflammation (CRP > or =5 mg/dl) and hypoalbuminemia were associated with an adjusted relative risk (ARR) of 3.8 for in-hospital mortality when compared with the reference (high albumin and low CRP).	17063065
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	Even in the absence of severe inflammation, the presence of severe hypoalbuminemia was associated with an ARR of 2.6 for in-hospital mortality, when compared with patients without hypoalbuminemia.	17063065
Upper Respiratory Infections, immunoglobulin A	Altered Intercellular Communication	The level of IgA and IgG antibody was significantly low in child patients with IgA and/or IgG immunoglobulin deficiencies, but was at the healthy control level in children with recurrent respiratory tract inflammation.	17064276
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	With the increase of portal inflammation, HPCs and ductular reaction extending from the periphery of the liver cirrhosis nodules to the liver parenchyma and the intermediate hepatocyte proliferation were observed.	17064468
Inflammation	Altered Intercellular Communication	The number of HPCs and the extent of ductular reaction increased significantly as the portal inflammation increased.	17064468
Inflammation, diabetic, Cardiovascular Diseases	Altered Intercellular Communication	Vascular phenotype and subclinical inflammation in diabetic Asian Indians without overt cardiovascular disease.	17064806
Inflammation, Carotid Intima-Media Thickness	Altered Intercellular Communication	Endpoints of the study were endothelial function, low-grade systemic inflammation (CRP) and carotid intima-media thickness (cIMT).	17064806
Inflammation, Arthritis, Gouty	Altered Intercellular Communication	AA amyloidosis caused by the chronic inflammation accompanying gouty arthritis is extremely rare and familial occurrence has not been described so far.	17065112
Diabetic Retinopathy, Inflammation	Altered Intercellular Communication	The increased vascular permeability and pathogenic angiogenesis observed in diabetic retinopathy are induced, at least in part, by local inflammation and vascular endothelial growth factor (VEGF).	17065523
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Inflammation may be linked to the pathogenesis of colorectal cancer.	17066508
Malignant tumor of colon, Inflammation	Altered Intercellular Communication	These results support our hypothesis that inflammation increases the risk of colon cancer.	17066508
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	I-type insulin-like growth factor receptor (IGF1R), hepatocyte derived growth factor receptor (HGFR), telomerase reverse transcriptase (TERT) and telomerase associated protein (TP-1) expression were evaluated immunohistochemically on formalin fixed paraffin embedded biopsy specimen from 10 mild, 10 moderate, and 10 severe active inflammation of ulcerative colitis and from 10 normal colonic tissue.	17066600
Inflammation	Altered Intercellular Communication	In moderately active inflammation only IGF1R expression was significantly higher compared to normal and to mild inflammation (p <0.005).	17066600
Inflammation	Altered Intercellular Communication	There were no regenerative signal expression alteration in severe inflammation compared to normal, and epithelial telomerase expression was not detectable in these cases.	17066600
Dental Plaque	Altered Intercellular Communication	Viral-induced inflammation is accompanied by beta-amyloid plaque reduction in brains of amyloid precursor protein transgenic Tg2576 mice.	17067295
Granulomatous inflammation, Anthracosis	Altered Intercellular Communication	Biopsy of the mass showed anthracosis and granulomatous inflammation.	17067407
Granulomatous inflammation, Neoplasms	Altered Intercellular Communication	Histologic examination showed intrinsic and surrounding granulomatous inflammation, but without tumor.	17067407
Inflammation	Altered Intercellular Communication	We suggest that one MEFV mutation may indeed be conferring a heightened inflammation as suggested by the increased frequency in inflammatory symptoms.	17067442
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	The role and diagnostic value of markers of inflammation is well recognized in acute coronary syndromes but it is uncertain in patients with stable coronary artery disease (CAD).	17067564
Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	The role of low grade inflammation as measured by C-reactive protein levels in the explanation of socioeconomic differences in carotid atherosclerosis.	17068002
Inflammation, Atherosclerosis	Altered Intercellular Communication	The role of inflammation as part of the explanation of socioeconomic differences in carotid atherosclerosis has not been specifically investigated.	17068002
Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	The association between SEP and carotid atherosclerosis as measured by carotid IMT and carotid plaque could only to a minor extent be referred to differences in low grade inflammation as measured by CRP.	17068002
Inflammation	Altered Intercellular Communication	To analyze the appearance of normal conjunctiva and conjunctival inflammation by in vivo confocal microscopy.	17068454
Conjunctivitis	Altered Intercellular Communication	It is a valuable aid in the differential diagnosis of conjunctival inflammation and thus may guide therapeutical decisions.	17068454
Uremia, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation but not oxidative stress is associated with beta-chemokine levels and prevalence of cardiovascular disease in uraemic patients.	17070067
Inflammation, Cardiovascular Diseases, Cancer-related fatigue, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation and oxidative stress (SOX) have been reported in patients with chronic renal failure (CRF), but their influence on beta-chemokines levels and cardiovascular disease (CVD) prevalence remains unknown.	17070067
Uremia, Inflammation	Altered Intercellular Communication	We assessed beta-chemokines, SOX markers and high sensitivity C-reactive protein (hs CRP) as a marker of inflammation in 40 uraemic patients, both with as well as without CVD and 20 controls.	17070067
Cancer-related fatigue, Inflammation	Altered Intercellular Communication	We documented that increased inflammation but not SOX were associated with significant elevation in plasma beta-chemokines levels and CVD prevalence in CRF patients not requiring dialysis.	17070067
Inflammation	Altered Intercellular Communication	These results suggest that dexamethasone may play an important role in the inhibition of the polymer-induced inflammation in the era of drug-eluting stents.	17070150
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	In addition to many traditional risk factors for coronary artery disease (CAD) development, enhanced oxidative stress and inflammation are serious conditions that may also be classified as novel risk factors.	17070511
ARCN1 gene, Pulmonary Ventilation, Airway structure, Lung hyperinflation, Chronic Obstructive Airway Disease, Impaired gas exchange	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a condition characterized by chronic airway inflammation and remodeling, lung parenchymal inflammation, and destruction resulting in expiratory airflow obstruction, hyperinflation of the lung with loss of elastic recoil, and impairment of gas exchange.	17070727
Inflammation, Allergic fungal sinusitis	Altered Intercellular Communication	This response varies from simple eosinophilic inflammation to classic allergic fungal sinusitis.	17071035
Cholecystitis, Chronic cholecystitis	Altered Intercellular Communication	To evaluate if contrast enhanced sonography (CES) can help to detect gallbladder inflammation and differentiate between acute and chronic cholecystitis.	17071039
Inflammation	Altered Intercellular Communication	The gallbladder wall of two patients with chronic inflammation and all patients (30/30) of the control group showed no enhancement.	17071039
Cholecystitis	Altered Intercellular Communication	CES is a feasible tool for detecting gallbladder inflammation.	17071039
Inflammation, Atherosclerosis	Altered Intercellular Communication	Our findings are consistent with a hypothesis that localized changes in cytokine expression generated by inflammation in atherosclerosis affect alternative splicing of the Ca(v)1.2alpha1 gene in the human artery that causes molecular and electrophysiological remodeling of Ca(v)1.2 calcium channels and possibly affects VSMC proliferation.	17071743
Wallerian Degeneration, Inflammation, Stanford Cancer Institute, Necrosis	Altered Intercellular Communication	SCI caused zones of pathological change, including areas of inflammation and necrosis in the acute cases, and cystic cavities with longer survival (Zone 1), mantles of less severe change, including axonal swellings, inflammation and Wallerian degeneration (Zone 2) and histologically intact areas (Zone 3).	17071951
Airway structure, Coughing	Altered Intercellular Communication	Airway inflammation is one mechanism responsible for cough induction.	17072042
Inflammation	Altered Intercellular Communication	Histological tests on a biopsy sample showed granulation tissue with non-specific chronic inflammation.	17072194
Pleural Effusion, CTCAE, Inflammation, Perihepatitis	Altered Intercellular Communication	Right pleural effusion may be caused by inflammation of the diaphragm associated with perihepatitis.	17072375
Inflammation, Thrombophlebitis	Altered Intercellular Communication	Suppurative thrombophlebitis is an inflammation of the vein wall by microorganisms and sometimes causes secondary metastatic abscess.	17073295
Communicable Diseases, Inflammation	Altered Intercellular Communication	Inflammation and infection complications of 2285 perineural catheters: a prospective study.	17073856
Communicable Diseases, Inflammation	Altered Intercellular Communication	The incidence and localization of local inflammation and infection associated with PNCs were assessed.	17073856
Inflammation, Swelling, Pain Distress Question	Altered Intercellular Communication	Local inflammation was defined as redness, swelling or pain on pressure at the catheter insertion site.	17073856
Communicable Diseases, Inflammation	Altered Intercellular Communication	Local inflammation occurred in 4.2% and infection in 3.2%.	17073856
Communicable Diseases, Inflammation	Altered Intercellular Communication	Anterior proximal sciatic catheters were associated with a lower risk of local inflammation (1.7%; P < 0.05) and infection (0.4%; P < 0.05).	17073856
Chronic infectious disease, Inflammation, Calcinosis	Altered Intercellular Communication	In chronic active infection, the clinical situation may also resemble acute infection as well findings of chronic inflammation such as calcification.	17074607
Airway structure, Inflammation, Asthma	Altered Intercellular Communication	Chronic airway inflammation is a basic pathology of bronchial asthma and it is important to control the inflammation by anti-inflammatory therapy mainly with steroids.	17075279
Sepsis, Inflammation, Tissue injury	Altered Intercellular Communication	Blocking CXCR4 and CXCL12 function may provide a novel therapeutic method for controlling systemic inflammation and tissue injury in sepsis.	17075377
Arthritis, Degenerative disorder of cartilage	Altered Intercellular Communication	Chondrocalcinosis, which can promote joint inflammation and cartilage degeneration, is highly prevalent in elderly white subjects.	17075853
Inflammation	Altered Intercellular Communication	The overproduction of ROS by activated polymorphonuclear leukocytes in chronic inflammation may lead to premature oxidative damage of the mtDNA.	17076616
Fibrous, Inflammation, Mycoses, Malignant Neoplasms	Altered Intercellular Communication	Chromoblastomycosis is a chronic cutaneous fungal infection where the presence of fibrous scars and continuous inflammation might be the propitious condition for the development of malignant neoplasms.	17076718
Inflammation, Redness, Neoplasms, Increased skin temperature, Pain	Altered Intercellular Communication	The five cardinal signs of inflammation: Calor, Dolor, Rubor, Tumor ... and Penuria (Apologies to Aulus Cornelius Celsus, De medicina, c. A.D. 25).	17077197
Inflammation	Altered Intercellular Communication	Our study suggests that an important molecular mechanism by GJWGM reduce inflammation, which may explain its beneficial effect in the regulation of inflammatory reactions.	17077523
Fibromatosis, Aggressive	Altered Intercellular Communication	These results indicate that sex steroid hormones might play an important role in the pathogenesis of desmoid tumors and could lead to the introduction of novel hormone therapeutic approaches in managing patients with recurrent desmoid tumors.	17077595
Fibromatosis, Aggressive	Altered Intercellular Communication	These results indicate that sex steroid hormones might play an important role in the pathogenesis of desmoid tumors and could lead to the introduction of novel hormone therapeutic approaches in managing patients with recurrent desmoid tumors.	17077595
Vasculitis	Altered Intercellular Communication	These findings indicate a persistent oxidative stress that might be associated with intravascular inflammation in patients during convalescence and release from hospital.	17077602
Hypernatremia, Inflammation, Malnutrition, Sepsis, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	Old age, inflammation, CVD, fluid overload and new comorbidities were all associated with malnutrition, with new comorbidities, mostly systemic infections, being the most significant risk factor.	17077624
Inflammation	Altered Intercellular Communication	These associations suggest potential mechanisms whereby inflammation may injure the vascular endothelium, but the recognition of how these mediators act in concert remain poorly characterized.	17077623
Inflammation, Kidney Failure, Vascular Diseases, Atherosclerosis	Altered Intercellular Communication	That the prevalence of atherosclerosis and markers of inflammation are increased in renal failure patients suggests that inflammation causes accelerated vascular disease.	17077623
Keratopathy, Inflammation	Altered Intercellular Communication	"Steel wool keratopathy": a clinical sign of chronic inflammation.	17077672
Keratitis, Keratitis, Herpetic	Altered Intercellular Communication	To introduce into the clinical nomenclature a sign frequently observed in our patients with persistent corneal inflammation associated with herpetic stromal keratitis.	17077672
Keratopathy, Chronic inflammation, Abnormal degeneration	Altered Intercellular Communication	Steel wool keratopathy seems to represent a focal region of stromal degeneration or deposition associated with chronic inflammation.	17077672
Inflammation, Stromal keratitis, Herpes Simplex Infections, herpesvirus 3, human, Herpetic whitlow	Altered Intercellular Communication	Although we most often observe this finding in patients with stromal keratitis secondary to HSV or VZV, we cannot exclude the possibility that this sign represents the sequelae of chronic/recurrent inflammation rather than a specific pathologic response to herpetic antigens.	17077672
Inflammation	Altered Intercellular Communication	Increased levels of CRP in the choroid may reflect a state of chronic inflammation that is a by-product of attenuated CFH complement-inhibitory activity in those who possess the CFH at-risk allele.	17079491
Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	In addition, the protein C -1641 AA genotype was associated with significantly more organ dysfunction and more clinical evidence of systemic inflammation (p < .05).	17080006
Sepsis, Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	Protein C -1641 AA genotype is associated with decreased survival, more organ dysfunction, and more systemic inflammation in patients having severe sepsis and with increased interleukin-6 levels after cardiopulmonary bypass surgery.	17080006
Cessation of life, Hypothyroidism	Altered Intercellular Communication	Subclinical hypothyroidism is linked to micro-inflammation and predicts death in continuous ambulatory peritoneal dialysis.	17082213
Syndrome	Altered Intercellular Communication	The relationship between fT3, CRP and serum albumin suggests that inflammation-malnutrition might be involved in the low T3 syndrome in CAPD patients.	17082213
palladium, Thyroid dysfunction	Altered Intercellular Communication	Thyroid dysfunction might be implicated in the pathogenic pathway which links micro-inflammation to survival in PD patients.	17082213
Inflammation	Altered Intercellular Communication	Histopathologic examination of these sections indicated that high CXCL12 expression correlated with increased tumor inflammation.	17082613
Granulomatous inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	A tracheotomy was performed; the histology showed infiltrating plasma cells, but no signs of vasculitis or granulomatous inflammation.	17082959
Pancreatitis	Altered Intercellular Communication	TSE-STIR was the best of the four modalities for delineating peripancreatic and pancreatic inflammation (P < 0.01).	17083111
Pancreatitis	Altered Intercellular Communication	TSE-STIR depicted definitive peripancreatic and pancreatic inflammation in 18 and 15 patients, respectively.	17083111
Pancreatitis	Altered Intercellular Communication	MDCT depicted only three cases of peripancreatic inflammation.	17083111
Alopecia, Perifolliculitis	Altered Intercellular Communication	Follicular inflammation in AGA has been associated with treatment resistance and progressive hair loss.	17083694
Alopecia	Altered Intercellular Communication	The female pattern of hair loss (diffuse hair loss affecting the central scalp with preservation of frontal hair line) coupled with follicular isthmic lymphocytic inflammation represents an unusual presentation, possibly a treatment resistant, inflammatory variant of AGA.	17083694
Hormone abnormality	Altered Intercellular Communication	Laboratory assessment for metabolic and hormonal abnormalities was unrevealing, and hair pull test was negative.	17083694
Inflammation, Asthma	Altered Intercellular Communication	IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?	17083726
Th17 Cells, Asthma	Altered Intercellular Communication	The data suggest that Th17 cell infiltration in asthmatic airways links T cell activity with neutrophilic inflammation in asthma.	17083726
Inflammation, Atherosclerosis, Plaque, Atherosclerotic	Altered Intercellular Communication	Given the importance of inflammation in atherosclerosis, we sought to determine if atherosclerotic plaque inflammation could be measured noninvasively in humans using positron emission tomography (PET).	17084256
Inflammation	Altered Intercellular Communication	When mean FDG uptake (mean TBR) was compared with mean inflammation (mean percentage CD68 staining) for each of the 17 patients, the correlation was even stronger (r = 0.85; p < 0.0001).	17084256
Inflammation	Altered Intercellular Communication	Simvastatin attenuates plaque inflammation: evaluation by fluorodeoxyglucose positron emission tomography.	17084257
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Inflammation plays a key role in progression and destabilization of atherosclerotic plaque.	17084257
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	18F-fluorodeoxyglucose PET is a promising tool for visualizing inflammation of atherosclerotic plaque.	17084257
Inflammation	Altered Intercellular Communication	18F-fluorodeoxyglucose PET visualized plaque inflammation and simvastatin attenuated it.	17084257
Inflammation	Altered Intercellular Communication	18F-fluorodeoxyglucose PET has a potential for visually monitoring plaque inflammation and the therapeutic effectiveness of statins.	17084257
Sepsis, Communicable Diseases, Inflammation	Altered Intercellular Communication	Based on recent in vitro data, we tested the hypothesis that microarray expression profiles can be used to diagnose sepsis, distinguishing in vivo between sterile and infectious causes of systemic inflammation.	17084318
Sepsis, Inflammation	Altered Intercellular Communication	Sepsis induces changes in mouse leukocyte gene expression that can be used to diagnose sepsis apart from systemic inflammation.	17084318
Inflammation, Atherosclerosis	Altered Intercellular Communication	Peroxisome proliferator-activated receptor (PPAR)-gamma2 has important effects to insulin sensitivity, atherosclerosis, inflammation and endothelial cell function.	17084528
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Recent studies indicate that chronic inflammation plays a pathogenic role in both the central nervous system (CNS) and periphery in Alzheimer's disease (AD).	17085001
Pain Distress Question, Inflammation, Pruritus	Altered Intercellular Communication	Of the 26 subjects who completed the follow-up period, 42% (11/26) were in complete remission with relief from itchiness, pain and inflammation.	17085943
Gastritis	Altered Intercellular Communication	Cellular responses in gastric inflammation are mediated by lipopolysaccharide of H. pylori, which activate monocytes to express cytokine expression and growth factors via CD14 and toll-like receptor 4 (TLR4).	17086894
Inflammation, Dryness (characteristic), Xerostomia	Altered Intercellular Communication	The patient had dry mouth, dry eyes, positive anti-SS-B antibody and salivary gland inflammation.	17087349
Hyperinsulinism	Altered Intercellular Communication	Inflammation affects lipid metabolism during recovery from hyperinsulinaemia.	17087780
Inflammation, Atherosclerosis, Diabetes Mellitus	Altered Intercellular Communication	Inflammation is an established contributor in atherosclerosis and several other common diseases including diabetes.	17087780
Inflammation, Hyperinsulinism	Altered Intercellular Communication	Inflammation is an important contributor to lipid and glucose metabolism during recovery from hyperinsulinaemia.	17087780
Communicable Diseases, Inflammation, Brain Injuries, Ischemic stroke	Altered Intercellular Communication	These data suggest that, although infection and other factors may contribute to systemic inflammation, the extent of acute brain injury after ischemic stroke is a major factor influencing the magnitude and variability of the APR.	17087970
Inflammation, Neoplasms, NCI CTEP SDC Gastroesophageal Cancer Sub-Category Terminology	Altered Intercellular Communication	Elevated tumour interleukin-1beta is associated with systemic inflammation: A marker of reduced survival in gastro-oesophageal cancer.	17088911
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Systemic inflammation is associated with adverse prognosis cancer but its aetiology remains unclear.	17088911
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	We investigated the expression of proinflammatory cytokines within normal mucosa from healthy controls and tumour tissue in cancer patients and related these levels with markers of systemic inflammation and with the presence of a tumour inflammatory infiltrate.	17088911
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	A chronic inflammatory infiltrate was observed in 75% of the cancer specimens and was associated with systemic inflammation (CRP: P = 0.01).	17088911
Inflammation, Neoplasms	Altered Intercellular Communication	However, the presence of chronic inflammation per se was not associated with altered cytokine expression within the tumour.	17088911
Inflammation	Altered Intercellular Communication	Both a chronic inflammatory infiltrate and systemic inflammation (CRP) were associated with reduced survival (P = 0.05 and P = 0.03, respectively).	17088911
Inflammation, Esophagogastric Junction, Neoplasms	Altered Intercellular Communication	Tumour chronic inflammatory infiltrate and tumour tissue IL-1beta overexpression are potential independent factors influencing systemic inflammation in oesophagogastric cancer patients.	17088911
HD Term Type, Inflammation, physiopathological, Atherosclerosis	Altered Intercellular Communication	In conclusion, our findings show that stiffening and atherosclerosis in non-symptomatic elderly HD patients are very common and they are related not only to hemodynamic changes (diastolic blood pressure), inflammation (hs-CRP, fibrinogen, ferritin) or metabolic dysfunction (increased i-PTH, abnormal lipid profile), but also to abnormal fat deposition (increased waist to hip ratio and waist circumference).	17089215
Pleurisy	Altered Intercellular Communication	An endoscopic lavage and debridement of the leak, prior to leak closure, seems to be helpful to reduce mediastinal and pleural inflammation.	17089284
Pleurisy	Altered Intercellular Communication	In this study, we tested the hypothesis that intrapleural C-reactive protein (CRP) might precisely quantify the postoperative pleural inflammation, offering potentially useful information for patient management.	17089319
Pleurisy	Altered Intercellular Communication	Pleural CRP levels of less than 25 mg/l on the second postoperative day indicate only a moderate pleural inflammation.	17089319
Hemifacial Spasm, Hyalinosis, Systemic, Inflammation, Communicable Diseases	Altered Intercellular Communication	This is a very rare cause of hemifacial spasm and clinicians should be on the look out for infective/inflammatory aetiology of hemifacial spasm; particularly in patients who present with recent onset HFS and have features of infection and or inflammation in the cranium.	17089501
Granuloma, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	The spectrum of histopathological changes of the liver showed epitheloid cell granulomas in 63 (42%), fatty changes in 49 (32.6%), inflammation in 60 (40%), sinusoidal congestion in 48 (32%) and fibrosis in 24 (16%) cases.	17089615
Granuloma, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	On comparing the granuloma and non-granuloma cases histological features, it was found that fatty changes and inflammation were more with granuloma formation but there was no difference in the degree of fibrosis in the two groups.	17089615
Inflammation	Altered Intercellular Communication	Inflammation, whereby ICAM-1 plays an important role, has been implicated in the pathogenesis of MI.	17089918
Respiratory Hypersensitivity, Airway Obstruction, Pneumonitis	Altered Intercellular Communication	It is associated with airway obstruction, increased airway hyper-responsiveness (AHR), and ongoing airway and lung inflammation dominated by CD8 lymphocytes and neutrophils.	17090574
Airway structure, ARCN1 gene, AHR wt Allele	Altered Intercellular Communication	To assess whether SNPs in ADAM33 are associated with the severity of AHR and airway inflammation in COPD.	17090574
ARCN1 gene, Airway structure	Altered Intercellular Communication	This is the first study revealing that SNPs in a gene that confers susceptibility to COPD in the general population-that is, ADAM33-are associated with AHR and airway inflammation in COPD.	17090574
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Type 2 diabetes (T2DM) is associated with chronic low-grade inflammation.	17090751
Inflammation	Altered Intercellular Communication	Adipose tissue (AT) may represent an important site of inflammation.	17090751
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation is deemed to play a crucial role in the pathogenesis of Alzheimer's disease (AD).	17090974
Inflammation, Dilated Cardiomyopathy Pathway	Altered Intercellular Communication	In the case presented here, a Chagasic dilated cardiomyopathy, we found electrocardiographic signs of subepicardial injury in the left free ventricular wall, related with histological findings of lymphocytic inflammation in these regions.	17091803
Inflammation, Demographics Domain, Metabolic Syndrome X, ETV3 wt Allele, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Type 2 diabetes (DM), metabolic syndrome (MetS), and inflammation are linked to reduced magnesium and fiber intakes; these associations are attenuated by adjustment for each of these nutrients.	17093158
Small cell carcinoma of lung, Paraneoplastic Syndromes, corticotropin	Altered Intercellular Communication	Ectopic adrenocorticotropic hormone syndrome is a paraneoplastic syndrome associated with small cell carcinoma.	17095061
Hypokalemia, corticotropin, Paresis, Small cell neuroendocrine carcinoma of bladder	Altered Intercellular Communication	We report what we believe to be the first case of ectopic adrenocorticotropic hormone syndrome associated with small cell carcinoma of the bladder that manifested as severe muscle weakness due to hypokalemia.	17095061
Inflammation	Altered Intercellular Communication	Expression of monocyte chemoattractant protein-1 and macrophage infiltration (inflammation) in addition to that of matrix metalloproteinases was unaffected by genotype after UUO.	17095590
Inflammation, Obesity	Altered Intercellular Communication	Our findings suggest that global obesity and, to a greater extent, central obesity directly affect inflammation, which in turn negatively affects muscle strength, contributing to the development and progression of sarcopenic obesity.	17095641
Arteritis	Altered Intercellular Communication	The levels of plasma PTX3 were increased in patients with arterial inflammation, especially UAP.	17095712
Inflammation, Pancreatitis, Necrosis	Altered Intercellular Communication	Severe acute pancreatitis is characterized by inflammation but may also be associated with accelerated apoptotic and necrotic pathways.	17095839
Inflammation, Corneal Ulcer	Altered Intercellular Communication	Three weeks later, the inflammation recurred and a corneal ulcer developed.	17095887
Inflammation	Altered Intercellular Communication	Organic foreign bodies in the eyelid can remain asymptomatic for a long period of time and can play a role in periocular inflammation.	17095887
Inflammation, Ulcer	Altered Intercellular Communication	The activated leukocytes that are the major part of the inflammation of skin ulcers are removed from the peripheral blood by LCAP.	17096696
Inflammation, Kidney Failure	Altered Intercellular Communication	Laboratory data indicated renal failure and the presence of systemic inflammation.	17096703
Inflammation	Altered Intercellular Communication	This is thought to be caused in part, by exposure to chronic systemic inflammation during the course of the disease.	17097659
Refractory anemias, Inflammation	Altered Intercellular Communication	We ascertained age, sex and disease duration, established CV risk factors, RA clinical manifestations and markers of inflammation.	17097659
Inflammation, ciliary vesicle	Altered Intercellular Communication	Systemic inflammation may amplify the age-related risk of CV disease.	17097659
Inflammation, Carotid Stenosis, atherosclerotic, Atherosclerosis	Altered Intercellular Communication	To better clarify the role of CD14 in atherosclerosis, we typed CD14 C-260T polymorphism in old Italian (Central of Italy) atherosclerotic patients with carotid stenosis related to lipid assessment, inflammation (soluble CD14, IL-6 serum levels) and IL-6, TNF-alpha, IL-10, Metallothioneins (MT) gene expressions in carotid plaques.	17098305
Chronic inflammation	Altered Intercellular Communication	Using Pearson's correlation, a high MT2A expression was associated with high IL-6, TNF-alpha, sCD14 and thereby with severe chronic inflammation.	17098305
Inflammation, Atheroma, Italy, Atherosclerosis	Altered Intercellular Communication	These data provide insight into the pathogenetic role of the CD14 C-260T polymorphism in atherosclerosis as -260TT genotype may favour increased inflammation in atheroma promoting possible worsening atherosclerosis, at least in Central of Italy elderly population.	17098305
Inflammation	Altered Intercellular Communication	Myeloperoxidase as a marker of increasing systemic inflammation in smokers without severe airway symptoms.	17098408
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	There is increasing evidence of systemic inflammation in patients with chronic obstructive pulmonary disease (COPD), but there is very little information on the development of systemic inflammation in smokers without severe airway symptoms.	17098408
Inflammation	Altered Intercellular Communication	This study provides evidence that male smokers without severe airway symptoms develop an increasing systemic inflammation during a 6-year period.	17098408
Airway structure, Asthma, MS4A2 wt Allele	Altered Intercellular Communication	The fraction of exhaled nitric oxide (Feno) is elevated in subjects with asthma and atopy, and it has been proposed to be a noninvasive marker of airway inflammation.	17099006
Inflammation	Altered Intercellular Communication	Histologic evidence of inflammation, especially polymorphonuclear cells, was increased in biopsies with high bacterial counts.	17099531
Inflammation, Fracture	Altered Intercellular Communication	The most common complications for titanium frameworks were resin or veneer fractures, soft tissue inflammation, and fractures (12.9%) of the metal frame.	17100745
Celiac Disease, Inflammation	Altered Intercellular Communication	Interleukin 18 maintains a long-standing inflammation in coeliac disease patients.	17100768
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumour necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK), a member of the TNF family, is a multi-functional cytokine that regulates cellular proliferation, angiogenesis, inflammation and apoptosis.	17100776
Inflammation, Colitis	Altered Intercellular Communication	Some drugs might be trigger factors of colonic inflammation in predisposed hosts, and others might only worsen self-evolving microscopic colitis.	17100977
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	First-degree relatives of patients with UC had greater FCC values and could have a subclinical intestinal inflammation.	17100982
Inflammation, Crohn Disease	Altered Intercellular Communication	Serum group IIA phospholipase A2 appeared to be the most sensitive marker of inflammation in Crohn's disease among the 22 blood tests compared.	17101550
Inflammation, Coronary Stenosis, Coronary Arteriosclerosis	Altered Intercellular Communication	The G allele of the TLR-4 gene, which is associated with a lower inflammation response, was associated with a lower risk of coronary stenosis but not with the occurrence of MI and hence is not a major factor in the development of coronary atherosclerosis.	17101559
Cessation of life, Inflammation, Myocardial Ischemia, Atherosclerosis	Altered Intercellular Communication	Recent evidence suggests that long-term exposure to particulate air pollution contributes to pulmonary and systemic oxidative stress, inflammation, progression of atherosclerosis, and risk of ischemic heart disease and death.	17101851
Pain Distress Question, Chronic neuropathic pain	Altered Intercellular Communication	Chronic neuropathic pain was associated with motor cortex disinhibition, suggesting impaired GABAergic neurotransmission related to some aspects of pain or to underlying sensory or motor disturbances.	17101886
Intraocular inflammation, Endophthalmitis, CTCAE	Altered Intercellular Communication	The most frequent ranibizumab-associated serious ocular adverse events were intraocular inflammation (11.4%) and endophthalmitis (1.9%; 4.8% if including presumed cases).	17101999
Intraocular inflammation	Altered Intercellular Communication	Although ranibizumab treatment increased the risk of serious intraocular inflammation, affected patients, on average, still experienced visual acuity benefit.	17101999
Bacterial keratitis, Inflammation, Ulcer	Altered Intercellular Communication	After treatment, the bacterial keratitis, shield ulcer, and inflammation in the anterior chamber disappeared.	17102679
Coma, Post-Head Injury	Altered Intercellular Communication	Post-traumatic inflammation is connected to polymorphonuclear neutrophil (PMN)-dysfunction characterized by reduced nuclear translocation of NF-kappaB during the post-traumatic period.	17102914
Clostridium difficile, Inflammation	Altered Intercellular Communication	A repeat pouch endoscopy at week 5 showed a complete resolution of mucosal inflammation of the pouch, while tests for Clostridium difficile toxins became negative.	17103037
Inflammation, NCI CTEP SDC Gastroesophageal Cancer Sub-Category Terminology	Altered Intercellular Communication	Host cytokine genotype is related to adverse prognosis and systemic inflammation in gastro-oesophageal cancer.	17103073
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	Systemic inflammation has been linked with reduced survival in cancer, however, the role of the host cytokine genotype versus tumour phenotype in the generation of this response is not clearly established.	17103073
Inflammation, Anemia, Chronic disease	Altered Intercellular Communication	The soluble transferrin receptor (sTfR) has become a highly specific parameter for the detection of iron deficits as it can differentiate between iron deficiency anaemia and anaemia of chronic disease, because of the lack of effect by associated inflammation, unlike ferritin.	17105489
Stenosis of duodenum, Inflammation, Stomach Neoplasms, Submucosal Route of Drug Administration	Altered Intercellular Communication	In this case, it was considered that the heterotopic pancreas caused chronic inflammation to form the gastric tumor, and submucosal abscess leading to the severe duodenal stenosis.	17106157
Hepatitis, Chronic	Altered Intercellular Communication	Our study highlights the usefulness of serum markers to investigate complex pathological situations, including distinct forms of chronic liver inflammation associated with CE.	17106545
Inflammation, Nephritis	Altered Intercellular Communication	We state that symptoms of a local inflammation caused by a foreign body in the bladder can imitate the symptoms of nephritis.	17106688
Doctor of Chiropractic, Inflammation, Heart failure	Altered Intercellular Communication	As targeting of etiology-related pathogenic pathways may be more efficient than current standard heart failure treatment, we obtained the genomic expression profile of a DCM subtype characterized by cardiac inflammation to identify possible new therapeutic targets in humans.	17106732
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Exacerbation	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) exacerbations are associated with increased airway and systemic inflammation, though relationships between exacerbation recovery, recurrent exacerbation and inflammation have not been previously reported.	17107990
Inflammation, Symptom aggravating factors	Altered Intercellular Communication	Frequent exacerbators had a smaller reduction in systemic inflammation between exacerbation onset and day 35 compared with infrequent exacerbators.	17107990
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Nonrecovery of symptoms at chronic obstructive pulmonary disease exacerbation is associated with persistently heightened systemic inflammation.	17107990
Inflammation, Symptom aggravating factors	Altered Intercellular Communication	The time course of systemic inflammation following exacerbation is different between frequent and infrequent exacerbators.	17107990
Inflammation, Corneal Opacity, Cataract, Leprosy, Atrophic	Altered Intercellular Communication	Iris atrophy continues to develop in 3% of patients with MB leprosy every year after they complete a 2-year course of MDT, and is associated with age, increasing loads of mycobacteria, subclinical inflammation, cataract and corneal opacity.	17108015
Inflammation, Idiopathic Interstitial Pneumonias, Damage	Altered Intercellular Communication	Several studies have implicated the role of inflammation in the pathogenesis of lung damage in idiopathic interstitial pneumonias (IIPs).	17108669
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	There is a localized distribution of inflammation in the normal, intervening and dense fibrosis areas of UIP for CD3+, associated with a lethal deterioration of the pulmonary function and poor survival.	17108669
Inflammation, Idiopathic Interstitial Pneumonias	Altered Intercellular Communication	Our findings provide further evidence of the importance of inflammation in the pathophysiology of IIPs.	17108669
Pharyngitis, Infectious Otitis Media	Altered Intercellular Communication	There was a significant relation between the degree of nasopharyngeal inflammation indicated by leukocyte infiltration images and the amount of S. pneumoniae and H. influenzae detected, which are the main pathogenic bacteria causing AOM (P < 0.01).	17109094
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Based on the increased expression of ICAM-1, VCAM-1, and their ligands LFA-1 and VLA-4 in patients with UC, we can conclude that these adhesion molecules play a key role in the adherence of lymphocytes and macrophages to endothelial cells maintaining the chronic inflammation.	17109102
Inflammation	Altered Intercellular Communication	LTC4S plays a key role in the process of inflammation as the rate limiting enzyme in the conversion of arachidonic acid to cysteinyl-leukotrienes, important mediators of inflammatory responses.	17110605
methyldopa, Inflammation	Altered Intercellular Communication	However, there are limited data on longitudinal associations between systemic markers of inflammation and AMD.	17110636
Inflammation, Aggressive behavior	Altered Intercellular Communication	Histological sections of the prostatic tissues of 52 patients were scored for the extent of inflammation and aggressiveness of inflammation, using the four point scale designed by Irani et al.	17111077
Inflammation	Altered Intercellular Communication	Extent of inflammation is graded from 0 to 3 according to the degree of invasion of inflammatory cells in prostate tissue.	17111077
Inflammation, Prostatic Glandular Cell	Altered Intercellular Communication	Aggressiveness of inflammation is graded from 0 to 3 according to the degree of contact or disruption of prostatic glandular epithelium by inflammatory cells.	17111077
Inflammation, Aggressive behavior	Altered Intercellular Communication	There was a significant correlation between inflammation and aggressiveness scores (r = 0.39, P < 0.01).	17111077
Inflammation, Aggressive behavior	Altered Intercellular Communication	Furthermore, median PSA levels in grades 1, 2 and 3 aggressiveness of inflammation were 4.4, 4.8 and 8.7 ng/ml, respectively.	17111077
Inflammation, Aggressive behavior	Altered Intercellular Communication	There was a significant difference between grades of aggressiveness of inflammation and PSA levels.	17111077
Inflammation, Thrombosis	Altered Intercellular Communication	Activated Factor XII (XIIa) is believed to participate in a number of pathophysiological processes including inflammation, thrombosis and fibrinolysis.	17111198
ARCN1 gene, Inflammation	Altered Intercellular Communication	Inflammation in sputum relates to progression of disease in subjects with COPD: a prospective descriptive study.	17112387
ARCN1 gene, Inflammation	Altered Intercellular Communication	We performed a prospective longitudinal study of subjects with COPD that related markers of sputum inflammation at baseline to subsequent disease progression.	17112387
Airway structure, Inflammation	Altered Intercellular Communication	Sputum markers of airway inflammation were quantified at baseline from spontaneously produced sputum in a sub-group (n = 38), and inflammation severity was related to subsequent disease progression.	17112387
ARCN1 gene, Inflammation	Altered Intercellular Communication	The data support a principal causative role for neutrophilic inflammation in the pathogenesis of COPD and suggest that the measurement of sputum inflammatory markers may have a predictive role in clinical practice.	17112387
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Complications of Diabetes Mellitus, Atherosclerosis	Altered Intercellular Communication	Lately, it was suggested that inflammation and activation of the innate immune system could be linked to type 2 diabetes pathogenesis and also to the development of common diabetic complications, mainly atherosclerosis.	17112620
Inflammation	Altered Intercellular Communication	In addition, 1,25-dihydroxyvitamin D(3) was able to modulate inflammation in these monocytes.	17112620
Inflammation, Pain Distress Question, Eye Movements, Erythema, Exophthalmos	Altered Intercellular Communication	On examination there was left exophthalmos, difficulty in coordinating eye movements, inflammation, erythema, and pain.	17112645
Inflammation, Hyperparathyroidism	Altered Intercellular Communication	Patients were subgrouped according to presence of hyperparathyroidism (mean iPTH > 350 pg/mL) and chronic inflammation (mean CRP > 8.5 mg/L) as group I (low iPTH, low CRP, n = 32), group II (high iPTH, low CRP, n = 32), group III (low iPTH, high CRP, n = 32), and group IV (high iPTH, high CRP, n = 31).	17112835
Inflammation, Hyperparathyroidism	Altered Intercellular Communication	We propose that hyperparathyroidism increases rHuEPO requirements and aggravates the negative effects of chronic inflammation in hemodialysis patients.	17112835
Inflammation, Coronary Artery Disease, hepcidin	Altered Intercellular Communication	Hepcidin, an acute-phase protein and a marker of inflammation in kidney transplant recipients with and without coronary artery disease.	17112858
Atherosclerosis	Altered Intercellular Communication	Inflammatory markers have been shown to play a role in the pathogenesis and progression of atherosclerosis, regarded as a chronic inflammatory condition.	17112858
ARCN1 gene, Airway structure, Pulmonary Emphysema, Bronchospasm, Bronchitis	Altered Intercellular Communication	COPD is a heterogeneous disease comprising a wide range of clinical phenotypes, depending on the degree to which emphysema, chronic bronchitis, reversible bronchospasm and small airways inflammation are present.	17113277
Inflammation, Necrosis, Edema, Mucous Membrane, Peeling of skin	Altered Intercellular Communication	Mucosal injury was assessed based on an accepted three-point scale which evaluates oedema, inflammation, mucosal necrosis or exfoliation, shortening of villi, and increase of goblet cells.	17113509
Inflammation, Thrombosis, Tidal Volume	Altered Intercellular Communication	Venous thrombosis (VT) and inflammation are two closely related entities.	17113632
Refractory anemias, Inflammation	Altered Intercellular Communication	It was postulated that the accelerated WBC telomere shortening in RA occurs as a result of exposure to chronic inflammation.	17114192
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	It remains unclear if inflammation itself may induce cancer, if inflammation is a result of tumor growth, or a combination of both exists.	17114654
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Baseline CRP levels seem to be a biomarker of chronic inflammation preceding lung cancer, even after subtracting a 5-year latent period.	17114654
Inflammation	Altered Intercellular Communication	Both chronic inflammation and impaired defense mechanisms resulting in chronic inflammation might explain these results.	17114654
Inflammation	Altered Intercellular Communication	The vast majority has inflammation of shoulders and hips, and half of them have increased FDG-uptake at the processi spinosi.	17114803
Herpes zoster disease, Bacterial Infections, Facial paralysis	Altered Intercellular Communication	In case of the co-occurrence of facial palsy and inflammation-like symptoms of the same ear, the differential diagnosis is focused on viral (herpes zoster) or bacterial diseases.	17115088
Inflammation, Vascular Diseases	Altered Intercellular Communication	TagSNP evaluation for the association of 42 inflammation loci and vascular disease: evidence of IL6, FGB, ALOX5, NFKBIA, and IL4R loci effects.	17115186
Inflammation, Carotid Artery Diseases	Altered Intercellular Communication	Evidence of genetic polymorphisms in inflammatory loci that predict severe carotid artery disease (CAAD) would suggest that this relationship is not secondary to other correlated factors, but related to inflammation itself.	17115186
Inflammation	Altered Intercellular Communication	These results support a role for genetic variation related to inflammation in CAAD and a causal role for specific gene products.	17115186
Inflammation, Renal Cell Carcinoma, Headache	Altered Intercellular Communication	Although the presence of headache did not correlate with cyst size, it was significantly more common in RCCs with: high- and iso intensity content on T1-weighted MR image (P= .0363), mucous content within the cyst (P= .0023), and intense chronic inflammation at the cyst wall (P= .0276).	17115992
Inflammation, Frontal headache, Headache, Hypopituitarism	Altered Intercellular Communication	Among 6 patients with histologically recognized intense inflammation, every patient had frontal headache (P= .0407), 5 patients had episodic headache (P= .0002), and 4 patients had associated hypopituitarism (P= .0073), none of which improved after surgical intervention.	17115992
Inflammation, Headache, physiopathological	Altered Intercellular Communication	Patients with episodic headache should undergo surgical treatment to prevent exacerbation of the inflammation that can result in irreversible endocrine dysfunction.	17115992
Chronic inflammation, Pathology, Neoplasms, Fibrosis Assessment, Metaplasia	Altered Intercellular Communication	We have little understanding of why this putative compensatory reaction so often fails to be appropriately regulated in ageing mammals, leading to such pathologies as chronic inflammation, fibrosis, metaplasia and neoplasia.	17116316
Inflammation	Altered Intercellular Communication	Fibrinogen plays a key role in coagulation and inflammation.	17116333
Kimura Disease	Altered Intercellular Communication	Histologic examination confirmed the diagnosis of Kimura disease, an uncommon chronic inflammatory condition.	17117118
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterised by chronic inflammation in pulmonary tissue and is also associated with systemic effects.	17118637
Inflammation, prostatitis, Prostatic Infection	Altered Intercellular Communication	Clinical prostatitis is also unlikely to be a risk factor, although possible roles for prostatitis in younger men and asymptomatic prostatic infection and inflammation cannot be ruled out.	17119041
gastric/duodenal, Inflammation	Altered Intercellular Communication	Gastric and duodenal biopsies found eggs, larval and adult forms present in the superficial mucosa with mild inflammation.	17121287
Inflammation, Metabolic Syndrome X, Diabetes Mellitus	Altered Intercellular Communication	We hypothesized that inflammation participates in the pathogenesis of diabetes mellitus and the metabolic syndrome by modulating levels of adiponectin and leptin.	17121520
Inflammation	Altered Intercellular Communication	It is possible that these organisms may contribute to chronic inflammation within the joints.	17122006
Inflammation	Altered Intercellular Communication	We present here 5 cases of photodistributed eruptions with virtual absence of histologic epidermal changes and dermal inflammation, yet all were described clinically as being "inflammatory" and erythematous.	17122492
Inflammation, Restenosis	Altered Intercellular Communication	Genetic factors appear to be important in the process of restenosis after percutaneous coronary intervention (PCI), as well as in inflammation, a pivotal factor in restenosis.	17122782
Inflammation, Keratitis	Altered Intercellular Communication	Severe reactive ischemic posterior segment inflammation in acanthamoeba keratitis: a new potentially blinding syndrome.	17123611
vascular inflammations, Acanthamoeba	Altered Intercellular Communication	To describe a newly recognized clinical syndrome in Acanthamoeba keratitis consisting of severe reactive ischemic posterior segment vascular inflammation.	17123611
Chorioretinitis, Amoeba genus, Acanthamoeba, Perivascular lymphocytic infiltrations	Altered Intercellular Communication	Histopathologic examination showed Acanthamoeba cysts in the cornea in 4 eyes, whereas it failed to demonstrate amebic cysts or trophozoites in the posterior segment of all eyes studied and unexpectedly revealed chronic chorioretinal inflammation with perivascular lymphocytic infiltration and diffuse neuroretinal ischemia in 4 of 5 eyes.	17123611
Inflammation, Acanthamoeba, Blood Coagulation Disorders	Altered Intercellular Communication	Prolonged Acanthamoeba keratitis can result in a severe sterile ischemic posterior segment inflammation that is potentially blinding, especially in patients with underlying hypercoagulation disorders.	17123611
Inflammation, Uveitis	Altered Intercellular Communication	Posterior uveitis with mild to moderate anterior uveitis simulating a nongranulomatous inflammation as evidenced by dust keratic precipitates, anterior chamber cells, and flare was noted in group 2.	17123618
Necrotizing granulomatous inflammation, Uveitis	Altered Intercellular Communication	Of the 33 patients with uveitis, 22 presented with nongranulomatous inflammation.	17123620
Inflammation, Uterine Fibroids	Altered Intercellular Communication	Pathological findings showed acute and chronic inflammation of the endometrium with abscess formation in an intramural leiomyoma.	17124417
Inflammation	Altered Intercellular Communication	Leptin, an adipocyte-derived factor, has been proposed to play a role in systemic inflammation.	17126131
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a pivotal role in the pathogenesis of atherosclerosis.	17126343
Inflammation, Restenosis	Altered Intercellular Communication	The CRP response to PCI, as a model to stimulate inflammation, is associated with an increased risk of clinical restenosis.	17126343
Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Effects of moderate-intensity exercise training on plasma biomarkers of inflammation and endothelial dysfunction in older patients with type 2 diabetes.	17126770
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Some plasma biomarkers of inflammation and endothelial dysfunction have been recently recognized as important cardiovascular risk factors.	17126770
Inflammation, Restenosis	Altered Intercellular Communication	Inflammation plays a pathogenic role in the development of restenosis after percutaneous coronary intervention (PCI).	17127484
Sandawe language	Altered Intercellular Communication	In SAD, a mixed flora of Gram-positive aerobic bacteria and anaerobic bacteria was observed that correlated with neutrophilic inflammation.	17127823
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Dissecting inflammation in ESRD: do cytokines and C-reactive protein have a complementary prognostic value for mortality in dialysis patients?	17130257
Cessation of life, Inflammation, Kidney Failure, Chronic	Altered Intercellular Communication	Because atherogenesis represents a type of chronic inflammation that involves multiple elements of the inflammatory-immune response, the simultaneous prediction power for death of C-reactive protein (CRP) and proinflammatory cytokines (IL-1 beta, IL-6, IL-18, and TNF-alpha) was tested in a cohort of 217 patients with ESRD.	17130257
Inflammation	Altered Intercellular Communication	In this model, the explained variation in mortality that was attributable to overall inflammation burden (+9.1%) was marginally higher (P = 0.06) than that provided by IL-6 alone (+6.1%).	17130257
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	IL-6 captures almost entirely the prediction power of the overall inflammation burden in patients with ESRD.	17130257
Inflammation, Chronic Kidney Diseases, Metabolic Syndrome X	Altered Intercellular Communication	These data demonstrate that patients with CKD have a high prevalence of IR, metabolic syndrome, and chronic inflammation and that the administration of the ARB olmesartan improves IR and inflammation markers in these patients.	17130263
Inflammation, Vascular Diseases	Altered Intercellular Communication	Irbesartan (300 mg once daily) reduces low-grade inflammation in this high-risk population, and this may reduce the risk of micro- and macrovascular disease.	17130503
Inflammation, Kidney Failure	Altered Intercellular Communication	Mild-to-moderate renal insufficiency is associated with significantly increased cardiovascular mortality in elderly men, which is partly explained by the increased prevalence of established risk factors, markers of coagulation, endothelium, and inflammation.	17132648
Intraocular inflammation, Corneal edema	Altered Intercellular Communication	Withdrawal of alendronate resulted in rapid resolution of intraocular inflammation and corneal edema.	17133063
Hyperlipidemia, Inflammation, Metabolic Syndrome X, Breast Carcinoma, Obesity	Altered Intercellular Communication	Obesity, hyperlipidemia, and metabolic syndrome are associated with increased rates of breast cancer and are systemic markers of chronic inflammation.	17133149
Inflammation, Carcinogenesis	Altered Intercellular Communication	Detecting CRP in NAF may indicate local mammary inflammation, which has been associated with carcinogenesis.	17133149
Fibrosis, Liver, Inflammation, Hepatocellular necrosis	Altered Intercellular Communication	In conclusion, HCV-specific IL-10-producing CD8 T cells, although not cytotoxic and unable to control viral replication, can attenuate hepatocellular necrosis, liver fibrosis, and inflammation mediated by bystander T cells, and may thus represent antigen-induced regulatory CD8 T cells.	17133491
Inflammation	Altered Intercellular Communication	Irrespective of which clinical criteria were applied to determine remission, the majority of patients continued to have evidence of active inflammation, as shown by findings on the imaging assessments.	17133543
Refractory anemias, Inflammation	Altered Intercellular Communication	This subclinical inflammation may explain the observed discrepancy between disease activity and outcome in RA.	17133543
Inflammation, Mural thrombus of heart, Infarction, Intestinal Diseases, Phlebitis	Altered Intercellular Communication	Ischemic intestinal disease due to mesenteric phlebitis is a rare entity with a pathological feature of inflammation of venous wall accompanying with the development of mural thrombosis and subsequent haemorrhagic infarction of intestine.	17134572
Inflammation, Wall of bladder	Altered Intercellular Communication	Interestingly, aside from noting mild inflammation of the gall bladder wall, microscopic examination of the specimen identified 2 fragments of benign thyroid tissue.	17134733
myonecrosis	Altered Intercellular Communication	Muscle necrosis was only observed in one case, in association with subglandular inflammation.	17134765
Inflammation, Skin Neoplasms	Altered Intercellular Communication	The expression of psoriasin in human skin tumours seems to be independent from differentiation and inflammation.	17136347
cell wall thickening, Colon diverticulum anatomic structure, Colitis	Altered Intercellular Communication	Colonic diverticula were identified in almost every patient (136/138, 98.6%); the majority had moderate colonic wall thickening (82/110, 74.5%) and moderate pericolonic inflammation (65/110, 59.1%).	17136376
Diverticulitis, Diverticulum, Colitis	Altered Intercellular Communication	Common CT findings of diverticulitis included presence of diverticula, moderate wall thickening, and pericolonic inflammation.	17136376
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	To evaluate the role of oxidative stress and inflammation in the aetiology of type 2 diabetes, we examined the association of oxidised LDL (ox-LDL) and soluble intercellular adhesion molecule-1 (sICAM-1) levels with type 2 diabetes incidence over 9 years in the Atherosclerosis Risk in Communities Study.	17136392
Inflammation, Fibrosis Assessment, Ulcerative Colitis	Altered Intercellular Communication	Real-time PCR showed a decrease of FN and ED-A expression during mucosal inflammation in CD in contrast to UC and a significant increase of FN and isoforms in CD fibrosis.	17136547
Inflammation, Cardiovascular Diseases, Refractory anemias, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Rheumatoid Arthritis	Altered Intercellular Communication	The risk of cardiovascular disease (CVD) is increased in patients with rheumatoid arthritis (RA), most likely because of increased systemic inflammation.	17136752
Airway structure, Noncommunicable Diseases	Altered Intercellular Communication	Also viruses and other non-infectious causes of exacerbation play a relevant role and also contribute to persisting airway inflammation.	17136956
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	We conclude that decorin production by lung fibroblasts of patients with severe emphysema is dysregulated after modulation with cytokines known to be important in smoking associated inflammation.	17136957
Inflammation, Idiopathic Interstitial Pneumonias, Nonspecific interstitial pneumonia	Altered Intercellular Communication	Little is known about the role of chemokines and their receptors interaction, which are essential for recruitment of selective lymphocyte subsets during inflammation, in the pathogenesis of idiopathic nonspecific interstitial pneumonia (NSIP).	17137778
Sialadenitis, Inflammation, Fibrosis Assessment, Lymphoplasmacytic Infiltrate	Altered Intercellular Communication	Biopsy specimens from the submandibular gland and retroperitoneal mass indicated sialadenitis and retroperitoneal fibrosis respectively, and showed severe fibrosis and inflammation with marked lymphoplasmacytic infiltration and IgG4-positive plasma cell infiltration.	17139126
Inflammation, Thrombosis	Altered Intercellular Communication	Platelets play an important role in monocyte TF expression, thrombosis and inflammation.	17139367
Inflammation, Skeletal muscle structure, Hypoxia	Altered Intercellular Communication	The role of cytokines in the pathogenesis of skeletal muscle injury in patients with hypoxia and inflammation remains unclear.	17139471
Inflammation, Dental Plaque, Dental caries	Altered Intercellular Communication	Caries activity (DeltaD(1-4)MFS) as well as plaque and gingival inflammation were recorded.	17140523
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is a major contributor to atherosclerotic vascular disease.	17141340
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	ECG (electrocardiogram) markers reflecting abnormal heart rate variability and abnormal repolarization as well as several biochemical markers reflecting inflammation, endothelial dysfunction, and procoagulation states were reported to show an association with increased cardiovascular mortality.	17141341
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	These results indicate that there is an association between ECG parameters and blood markers reflecting endothelial function and inflammation in coronary artery disease patients.	17141341
Inflammation, varicella zoster	Altered Intercellular Communication	Viral invasion of the motoneurons and the subsequent inflammation in the anterior horn cells by the varicella zoster virus results in a weakness in the area of the cutaneous eruption.	17141648
Refractory anemias, Inflammation	Altered Intercellular Communication	Our data indicate a novel pathogenic pathway in which overexpression of negative costimulatory molecules to restrict synovial inflammation in RA is overruled by the excessive production of soluble costimulatory molecules.	17142787
Inflammation	Altered Intercellular Communication	This observation suggests that reduced systemic inflammation may be one of the mechanisms through which physical activity leads to reduced cardiovascular risk.	17143130
Inflammation, Restenosis, Atherosclerosis	Altered Intercellular Communication	Furthermore, inflammation is suggested to be a pivotal mechanism linking atherosclerosis and restenosis.	17143564
Inflammatory Bowel Diseases, Carcinoma	Altered Intercellular Communication	Our results show that FHIT protein expression is completely absent or reduced in IBD, suggesting that the FHIT gene might be associated with the oncogenesis and progression of IBD, an early event from inflammatory conditions to carcinoma in IBD.	17143956
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	[Markers of inflammation and large artery compliance in patients with chronic renal failure].	17144091
Inflammation, Atherosclerosis	Altered Intercellular Communication	Chronic inflammation is a widely accepted pathophysiologic factor of development and progression of atherosclerosis.	17144091
Arterial Stiffness, Inflammation, palladium, Kidney Failure, Chronic	Altered Intercellular Communication	The impact of chronic inflammation on arterial stiffness was not analyzed up to now in patients with end-stage renal disease treated with peritoneal dialysis (PD).	17144091
Tumor necrosis, Inflammation	Altered Intercellular Communication	In all patients Tumor Necrosis Factor alpha (TNF alpha), interleukin 6 (IL-6), C- reactive protein and fibrinogen were assayed as 'markers of inflammation'.	17144091
palladium, Inflammation, Aortic Stiffness	Altered Intercellular Communication	Chronic, uremia-dependent inflammation may be one of the factors influencing aortic stiffness in patients treated with PD.	17144091
Communicable Diseases, Chlamydia, Cerebrovascular Physiology	Altered Intercellular Communication	The association of carotid plaque inflammation and Chlamydia pneumoniae infection with cerebrovascular symptomatology.	17145421
Atherosclerosis of renal artery, Communicable Diseases, Inflammation, Cerebrovascular Disorders	Altered Intercellular Communication	Inflammation and infection have been implicated in the pathogenesis of carotid artery atherosclerosis, but their role in cerebrovascular disease symptomatology is not so well defined.	17145421
Inflammation, Atheroma, Communicable Diseases, Chlamydia, Tumor necrosis	Altered Intercellular Communication	We hypothesized that carotid disease symptomatology was associated with specific serologic markers of inflammation and Chlamydia pneumoniae infection and the presence of the pathogen and concentration of tumor necrosis factor-alpha (TNF-alpha) on the atheroma.	17145421
Tumor necrosis, Carcinogenesis	Altered Intercellular Communication	Tumor necrosis factor-alpha increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: a potential mechanism for inflammation-induced carcinogenesis.	17145855
Inflammation, Prostate	Altered Intercellular Communication	Inflammation has been implicated in the development of many human epithelial cancers, including those of the stomach, lung, colon, and prostate.	17145855
Tumor necrosis, Inflammation, Traumatic injury	Altered Intercellular Communication	Tumor necrosis factor-alpha (TNF-alpha) is a potent pleiotropic, proinflammatory cytokine produced by many cells in response to injury and inflammation.	17145855
Inflammation	Altered Intercellular Communication	The data are consistent with a model that directly links inflammation and DNA damage through the production of H(2)O(2) by SMO/PAOh1.	17145855
Inflammation, Carcinoma, Ovarian Epithelial	Altered Intercellular Communication	Further, these results suggest a common mechanism by which inflammation from multiple sources can lead to the mutagenic changes necessary for the development and progression of epithelial cancers.	17145855
Restenosis	Altered Intercellular Communication	Gene ontology analysis demonstrated the prominence of cell proliferation programs in ISR and inflammation/immune programs in de novo restenosis.	17145989
Inflammation	Altered Intercellular Communication	It might have been misinterpreted as an active process, such as inflammation, in the skin.	17146113
Acute and chronic inflammation, Malignant Neoplasms, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Repeated endoscopic biopsies revealed a non-specific acute-on-chronic inflammation consisting of non-caseating granulomas, with no evidence of malignancy.	17148804
Inflammation, Granulomatosis with polyangiitis, Periaortitis, Back Pain	Altered Intercellular Communication	Wegener granulomatosis with back pain, periaortitis, and dural inflammation developing while receiving monthly cyclophosphamide.	17149061
Inflammation, Granulomatosis with polyangiitis, Periaortitis	Altered Intercellular Communication	This case describes the clinical course of the rare complication of Wegener granulomatosis, periaortitis, and dural inflammation despite monthly cyclophosphamide and demonstrates the role of magnetic resonance imaging and FDG-PET in their diagnosis.	17149061
Inflammation, Acute heart failure	Altered Intercellular Communication	Interventional and medical treatment of acute heart failure due to inflammation: four cases.	17149677
Hyperglycemia, Dyslipidemias, Inflammation	Altered Intercellular Communication	The variability of hyperglycemia, dyslipidemia, and inflammation with age progression was also studied for comparison.	17151300
Inflammation	Altered Intercellular Communication	Marked inflammation was prominent only in Groups C and D. This article indicates that different biochemical parameters may be used for the assessment of CVD risk in T2DM patients of variable age.	17151300
Inflammation, Occluded, Stenosis Morphology	Altered Intercellular Communication	As a result of the inflammation, stenosis, occlusion or dilatation of the involved vessels may occur and cause a wide range of symptoms.	17152333
Inflammation, Vitreous strands	Altered Intercellular Communication	Biomicroscopy of the retina showed an atypical, solitary, yellowish-white lesion in the macula of both eyes with no inflammation of the vitreous.	17152549
Nasal Polyps, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Nasal polyps are the results of chronic inflammation of nasal mucosa.	17152808
Inflammation, Acute Cholecystitis	Altered Intercellular Communication	The blood flow velocity in the wall of the gallbladder is an indicator of the degree of inflammation in acute cholecystitis.	17153431
Inflammation, Acute Cholecystitis	Altered Intercellular Communication	The gallbladder wall blood flow velocity indicated the degree of inflammation in the acute cholecystitis patients.	17153431
Cholecystitis	Altered Intercellular Communication	The RI of the blood flow in the gallbladder wall may also be an effective method of monitoring gallbladder inflammation.	17153431
Inflammation, Inflammatory disorder	Altered Intercellular Communication	This clinical course suggested that chronic inflammation of the pituitary had spread to the dura mater, a clinical condition differing from parasellar chronic inflammatory disease (PSCID).	17154037
Inflammation, Pruritus, Superinfection, Dermatitis	Altered Intercellular Communication	Although benign and generally self-limited, this condition is contagious and can lead to complications such as inflammation, pruritus, dermatitis, bacterial superinfection, and scars.	17156002
Airway structure, Inflammation	Altered Intercellular Communication	Combined topical steroid and combined mediator antagonism both attenuated systemic inflammation in the unified allergic airway, but only the former reduced bronchial and nasal inflammatory markers.	17156345
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	These results suggest that systemic hsCRP levels reflect synovial inflammation in OA patients, perhaps by means of synovial IL-6 production.	17157039
Inflammation, Electrocardiogram: myocardial infarction (finding), Depression, CTCAE	Altered Intercellular Communication	Hospitalization for depression is associated with an increased risk for myocardial infarction not explained by lifestyle, lipids, coagulation, and inflammation: the SHEEP Study.	17157824
Inflammation, Comorbidity	Altered Intercellular Communication	Adjustment for lifestyle, lipid profile, coagulation, inflammation, prior cardiovascular events, and comorbidity only partly decreased the observed association.	17157824
Inflammation, Atherosclerosis	Altered Intercellular Communication	Placenta growth factor (PlGF) mediates angiogenesis and inflammation, but its role in human atherosclerosis is unknown.	17157858
Inflammation, atherosclerotic	Altered Intercellular Communication	This study was designed to test the hypothesis that PlGF-expression in human atherosclerotic carotid plaques is related to inflammation, vascularization and clinical plaque instability.	17157858
Inflammation, Dental Plaque, Atherosclerotic lesion	Altered Intercellular Communication	PlGF-expression within human atherosclerotic lesions is associated with plaque inflammation and microvascular density, suggesting a role for PlGF in plaque destabilization and, thus, in clinical manifestation of the disease.	17157858
Inflammation, neuroborreliosis	Altered Intercellular Communication	Since complement is a main player in early inflammation, we monitored the concentration and activation of complement in plasma and cerebrospinal fluid from 298 patients, of whom 23 were diagnosed with neuroborreliosis.	17157926
Ulcer, Granulomatous inflammation, Necrosis	Altered Intercellular Communication	The biopsy of this ulcer showed granulomatous inflammation and Langhans type giant cells, without necrosis.	17157966
Inflammation, Bursitis, Edema	Altered Intercellular Communication	Hypoechogenicity, increased tendon thickness, peritendinous oedema and bursitis were considered signs of active inflammation.	17158138
Inflammation	Altered Intercellular Communication	These findings are compatible with a critical role for inflammation in RA-associated premature mortality.	17158824
Medical Device Contamination during Use, Inflammation, Dysplasia, Ulcer	Altered Intercellular Communication	It is demonstrated that viral contamination is associated with immunodeficiency, maintains chronic inflammation in ulcer and promotes dysplasia progress.	17159858
Inflammation, Anemia	Altered Intercellular Communication	The association between anaemia and a poor nutritional status as well as the presence of inflammation has already been documented.	17160447
Myocardial Infarction	Altered Intercellular Communication	The mechanistic and clinical implications of attenuated periprocedural inflammation and myocardial necrosis with a strategy of GP IIb/IIIa inhibition warrant further investigation.	17161243
Inflammation, Dyslipidemias, Systolic hypertension, physiopathological, Chronic Kidney Diseases	Altered Intercellular Communication	Insulin resistance, inflammation, systolic hypertension, and increased pulse pressure, but not dyslipidemia, were associated with vascular dysfunction and may be targets for future interventional strategies to reduce CVD risk in patients with CKD.	17162147
Granulomatous inflammation	Altered Intercellular Communication	A biopsy specimen of the mass demonstrated a granulomatous inflammation without caesation necrosis.	17162610
Inflammation, Carcinogenesis, Atherosclerosis	Altered Intercellular Communication	Fifteen (15)-lipoxygenase type 1 (15-LO-1, ALOX15), a highly regulated, tissue- and cell-type-specific lipid-peroxidating enzyme has several functions ranging from physiological membrane remodeling, pathogenesis of atherosclerosis, inflammation and carcinogenesis.	17164146
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP) is an inflammation protein that may play a role in the pathogenesis of cardiovascular disease (CVD).	17164456
Inflammation, diabetic	Altered Intercellular Communication	Whether resistance training modulates inflammation in muscles of diabetic patients remains unknown.	17166396
Inflammation, Uveitis	Altered Intercellular Communication	The present observations suggest that aqueous humour levels of PEDF may be a marker of inflammation in uveitis.	17166895
Airway structure, Asthma	Altered Intercellular Communication	Chronic airway inflammation is a feature of asthma.	17166987
Airway structure, Asthma, Hyperreactivity	Altered Intercellular Communication	EBC cys-LTs may be useful as a noninvasive marker assessing airway inflammation and hyperreactivity in children with asthma.	17166987
Inflammation	Altered Intercellular Communication	Imbalance of matrix metalloproteinases and tissue inhibitors of metalloproteinases (MMPs/TIMPs) takes part in age-related renal fibrosis; so does molecular inflammation.	17167153
Inflammation	Altered Intercellular Communication	Our results indicated that TIMP-1 could promote age-related renal fibrosis, which was partly attributed to enhancing inflammation through upregulation of ICAM-1.	17167153
Inflammation	Altered Intercellular Communication	Platelets are involved in the pathogenesis of chronic inflammation.	17168422
Gingivitis, Oral infection, Dental caries, Hemorrhage	Altered Intercellular Communication	Data on pharmacologic, oral hygienic, dietary, and surgical preventive measures for the control of recurrent oral infections, dental caries, gingival inflammation and risk of surgical bleeding are described.	17168629
Thrombus, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	Platelets are an important element in the thrombotic process, inflammation and cancer progression.	17169411
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	We tested the hypothesis that there is a relationship between platelet activation and inflammation in colorectal cancer patients (CRC).	17169411
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	We measured soluble (s) P-selectin (marker of platelet activation), interleukin-6 (IL-6) and C-reactive protein (CRP) (indexes of inflammation) in 42 CRC patients and 38 healthy subjects.	17169411
Inflammation	Altered Intercellular Communication	Today the focus is on the stimulation of mononuclear cells by bacterial fragments contributing to chronic inflammation associated with long-term haemodialysis therapy, and which has led to suggestions regarding the desirability of using ultra-pure dialysis fluid to prevent or to delay complications associated with their presence.	17170540
Unknown (origin) (qualifier value), Inflammation, Retractile Mesenteritis	Altered Intercellular Communication	Retractile mesenteritis is a rare, idiopathic condition characterized by nonspecific inflammation of the mesenteric adipose tissue.	17171198
Oncocytic Neoplasm, Hyperplasia, Chronic inflammation, Pancreatic aplasia	Altered Intercellular Communication	The adjacent gastric cardiac mucosa showed hyperplasia, oncocytic, and pancreatic acinar metaplasia, and mild chronic inflammation.	17172496
Communicable Diseases, Inflammation	Altered Intercellular Communication	After surgery, the inflammation was controlled without any signs of recurrent infection.	17172906
Inflammation, Atherosclerosis	Altered Intercellular Communication	Toll-like receptors mediate the innate immune response triggered by pathogen-associated molecular patterns, and atherosclerosis can be considered a state of chronic inflammation whereby immune system cells accumulate within the intima of the arterial wall.	17172927
Kidney Failure, Chronic, Inflammation, Fibrosis Assessment, Kidney Failure	Altered Intercellular Communication	Since TNF-alfa and IL-10 are involved in regulation of inflammation, and TGF-beta 1 can induce fibrosis and renal insufficiency - dominant features of end-stage renal disease (ESRD), we explored the hypothesis that polymorphisms of these cytokine genes may be possible genetic susceptibility factors for the progression of renal failure.	17173255
Hemangioma	Altered Intercellular Communication	Our observations suggest that a hormonal stimulus probably plays no role in the pathogenesis of angioma serpiginosum.	17173473
Communicable Diseases, Neoplasms	Altered Intercellular Communication	The errors grouped by diseases were as follows: 6/54 (11%) for tumors, 10/30 (33.3%) for inflammatory conditions, 1/20 (5%) for infectious diseases, 3/12 (25%) for alopecia/acne and 1/5 (20%) for others.	17173824
Hepatic inflammation, Hepatitis C	Altered Intercellular Communication	A reduction in selective immune pressure during the course of chronic hepatitis C correlates with diminished biochemical evidence of hepatic inflammation.	17174372
Parkinson Disease, Inflammation, palladium	Altered Intercellular Communication	Recent reports have proven the importance of genetic factors and inflammation in the pathogenesis of sporadic Parkinson's disease (PD).	17174426
Inflammation	Altered Intercellular Communication	These findings suggest that nociceptive but not sympathetic neurons are primarily involved in the attraction of opioid-containing leukocytes during early stages of inflammation.	17174527
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	The renin-angiotensin-aldosterone system and inflammation are supposed to play a key role in the pathogenesis of atrial fibrillation (AF).	17174648
Inflammation, Calcified (qualifier), Atherosclerosis	Altered Intercellular Communication	FDG-avid foci may represent a dynamic process, transient inflammation, whereas CT calcifications may indicate stable atherosclerosis.	17174810
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The role that inflammation plays in cancer is puzzling.	17175197
Inflammation, Thrombosis, Corneal Endothelial Cell Loss, Atherosclerosis, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	Since inflammation and endothelial cell damage or injury are invariably associated with thrombosis, atherosclerosis, and their major clinical consequences, resistin may play a role to link inflammation and CVD.	17175295
Inflammation	Altered Intercellular Communication	The relation of elevated resistin levels to markers of inflammation may represent a novel link between these conditions and adipocytokines.	17175295
Inflammation	Altered Intercellular Communication	There are studies to suggest that the persistence of aluminum particulate may cause ongoing inflammation despite removal from exposure.	17175666
Granuloma, Helicobacter pylori, Inflammation	Altered Intercellular Communication	Multiple endoscopic biopsies of the stomach showed one granuloma, chronic inflammation and Helicobacter Pylori.	17175696
Inflammation, Orbital Pseudotumor	Altered Intercellular Communication	On her second ED visit later the same day, a diagnosis of orbital pseudotumour was made after computed tomography revealed inflammation of the sclera, optic nerve, muscle and adipose tissue within the orbit.	17175875
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide has been extensively investigated as a non-invasive marker of airway inflammation.	17175971
Airway structure, Sleep Apnea, Obstructive	Altered Intercellular Communication	Some authors have suggested that morning FE(NO) in obstructive sleep apnea syndrome (OSAS) patients is elevated due to inflammation of upper airways, while others have not found any differences between patients and healthy subjects.	17175971
Inflammation, Malnutrition, Diabetes Mellitus	Altered Intercellular Communication	At basal, 70% of the patients had carotid plaques, 32% had symptomatic CVD, 38% had malnutrition, 30% had inflammation (CRP > or = 1 mg/dl) and 23% had diabetes mellitus, respectively.	17176913
Inflammation, Thrombosis, Carcinogenesis, Lip and Oral Cavity Carcinoma	Altered Intercellular Communication	In view of the recently found contribution of factors associated with thrombosis and inflammation to carcinogenesis, we investigated the possible association of interleukin-6 (IL-6) with an increased risk of oral cancer.	17177164
Trachoma , Perifolliculitis	Altered Intercellular Communication	Prevalence of signs of active trachoma in children aged 1-9 y was: trachomatous inflammation-follicular (TF) = 57.5% (95% confidence interval [CI], 54.5%-60.4%); trachomatous inflammation-intense (TI) = 39.8% (95% CI, 36.3%-43.5%); and TF and/or TI (active trachoma) = 63.3% (95% CI, 60.1%-66.4%).	17177597
Inflammation, Arteriosclerosis	Altered Intercellular Communication	These diseases together have shown bad results because of the process of accelerated arteriosclerosis, structural changes of myocardium, oxidative stress, inflammation, increased activities of sympathetic nervous system (SNS), increased activities of a renin-angiotensin-aldosterone system (RAAS) (1).	17177647
Inflammation, Rosacea	Altered Intercellular Communication	Patients with rosacea and red facial skin often show sensitivity to skin care products which can exacerbate inflammation and subjective irritation.	17177744
Inflammation	Altered Intercellular Communication	Acute peroperative inflammation and low extraction forces were related to denudation of the roots.	17178506
Inflammation, Depression, CTCAE, Coronary heart disease	Altered Intercellular Communication	[Platelet activation and inflammation markers in patients with coronary heart disease and depression].	17180929
Inflammation, Depression, CTCAE, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	To study morphological features and functional activity of platelets, their relations with the level of inflammation markers in coronary heart disease (CHD) patients with depression.	17180929
Vasculitis, Complication Aspects, Depression, CTCAE, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Depression stimulates functional activity of platelets, is a factor of risk of intravascular inflammation and contributes to development of thrombotic complications in CHD patients.	17180929
Ocular Hypertension, Inflammation	Altered Intercellular Communication	Ocular hypertension, inflammation or other complications did not develop.	17181619
Inflammation	Altered Intercellular Communication	Local VIP production in PMR synovial tissue might contribute to the typical musculoskeletal discomfort and it may have a role in the immunomodulation of synovial inflammation.	17181926
Inflammation	Altered Intercellular Communication	The degree of B lymphocyte infiltration is associated with more pronounced synovial inflammation and with the presence of plasma cells and lymphoid follicles in more severe cases.	17182596
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Inflammation is associated with the pathogenesis of coronary atherosclerosis, although the mechanisms remain unclear.	17182600
Inflammation	Altered Intercellular Communication	Systemic inflammation triggered by cardiopulmonary bypass increased plasma levels of the IFN-gamma axis, but not that of IL-18.	17182600
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	In conclusion, circulating IL-12 may provide a mechanistic link between inflammation and Th1-type cytokine production in coronary atherosclerosis.	17182600
Increased insulin level, Primary malignant neoplasm, Inflammation, Depressed mood	Altered Intercellular Communication	These lifestyle patterns may increase cancer risk by several mechanisms including increased estrogens and testosterone, hyperinsulinemia and insulin resistance, increased inflammation, and depressed immune function.	17182820
Inflammation, Neoplasms, Cyst, Hypertrophy, teratologic	Altered Intercellular Communication	An enlargement may represent a variation of normal anatomic structures, inflammation, cysts, developmental anomalies and neoplasm.	17183185
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Kidney function and markers of inflammation in elderly persons without chronic kidney disease: the health, aging, and body composition study.	17183246
Inflammation	Altered Intercellular Communication	As cystatin C may detect small changes in kidney function not detected by estimated glomerular filtration rate, we evaluated the association between cystatin C and serum markers of inflammation in older adults with estimated glomerular filtration rate >or=60.	17183246
Interstitial inflammation	Altered Intercellular Communication	Older age was associated with increased nuclear p16(INK4a) expression in tubules (P=0.01), and interstitial inflammation was associated with increased nuclear p16(INK4a) expression in interstitial cells (P=0.001).	17183247
Infarction, Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Inflammation, involving cytokine/chemokine expression, occurs after stroke and deteriorates its course with leukocyte-mediated brain infarct progression.	17183455
Inflammation, Mapuche Language	Altered Intercellular Communication	We recommend the management of ARN to include prompt diagnosis; prophylactic argon laser retinopexy, preferably within the first 2 weeks to reduce risk of RD; systemic acyclovir; and corticosteroids to control the severe inflammation associated with ARN.	17184841
Granulomatous inflammation, Pathological Dilatation, Traumatic injury, Necrosis	Altered Intercellular Communication	Histology showed large artery wall injury with acute leucocytoclastic inflammation, fibrinoid necrosis, granulomatous inflammation, and ectasia of vessel wall.	17186544
Tick bite (disorder), Vascular Diseases, Inflammation	Altered Intercellular Communication	Thrombogenic vasculopathy with diffuse neutrophilic inflammation: a histologic manifestation of a tick bite.	17186789
Inflammation, Metabolic Syndrome X, MS gene	Altered Intercellular Communication	In recent years some studies have shown that metabolic syndrome (MS) is associated with inflammation, indicated by high-sensitivity C-reactive protein (hsCRP), but there have been few population-based studies, especially in Japan.	17186974
Inflammation, Hepatitis	Altered Intercellular Communication	Histologically, positive anti-gp210 antibodies was most significantly associated with more severe interface hepatitis and lobular inflammation, whereas positive anticentromere antibodies was most significantly associated with more severe ductular reaction.	17187436
Inflammation	Altered Intercellular Communication	We observed signs of inflammation in the ocular fluid in 2 of 3 patients by the determination of different cytokines.	17187864
Chronic heart failure, Deterioration, Congestive heart failure	Altered Intercellular Communication	The disease presentation of chronic heart failure (CHF) is considered to progress with metabolic deterioration, underlined by changes in adipose associated hormones (adipocytokines).	17187880
HSPG2 wt Allele, Inflammation, Stevens-Johnson Syndrome, CTCAE	Altered Intercellular Communication	To compare the resolution of inflammation and long-term results of cultivated and conventional limbal stem cell transplantation (LSCT) in a patient with Stevens-Johnson syndrome (SJS).	17188066
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation and IL-8 levels decreased more rapidly in the eye with cultivated LSCT.	17188066
vascular inflammations, Chronic heart failure, Endothelial dysfunction, Congestive heart failure	Altered Intercellular Communication	Vascular inflammation and endothelial dysfunction are evident in patients with chronic heart failure (CHF).	17188380
Inflammation, Data types - Address	Altered Intercellular Communication	Primary focus was placed on understanding how inflammation plays a role in AD pathogenesis.	17188679
nervous system disorder, Inflammation	Altered Intercellular Communication	Gene ontology analysis revealed that the most differentially expressed genes related to nervous system development and function and neurological disease followed by genes involved in inflammation and immunological signaling.	17188679
Inflammation, Data types - Address	Altered Intercellular Communication	Together, these findings open up new avenues of investigation and possible therapeutic strategies targeting inflammation and amyloid clearance in AD patients.	17188679
Cataract, Inflammation, Manufactured sign	Altered Intercellular Communication	One week later, a white cataract was noticed on examination in the absence of systemic or ocular signs of inflammation.	17189155
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	A visfatin promoter polymorphism is associated with low-grade inflammation and type 2 diabetes.	17189536
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Influence of metabolic syndrome on biomarkers of oxidative stress and inflammation in obese adults.	17189537
Inflammation, Overweight	Altered Intercellular Communication	To determine whether antioxidant (AOX) supplementation attenuates post-exercise oxidative stress and contributors to oxidative stress (inflammation, blood lipids) in overweight young adults.	17189550
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	Nepafenac ophthalmic suspension 0.1% for the prevention and treatment of ocular inflammation associated with cataract surgery.	17189793
Cataract, Inflammation, Pain Distress Question	Altered Intercellular Communication	To determine whether nepafenac ophthalmic suspension 0.1% decreases the incidence and severity of inflammation and pain after cataract surgery with posterior chamber intraocular lens implantation.	17189793
Cataract, Pain Distress Question, Inflammatory abnormality of the eye	Altered Intercellular Communication	Nepafenac ophthalmic suspension 0.1% was safe and effective for preventing and treating ocular inflammation and pain associated with cataract surgery.	17189793
Cancer-related fatigue, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic renal failure (CRF) patients suffer from a chronic inflammation.	17190649
Cancer-related fatigue, Inflammation	Altered Intercellular Communication	The elevation of pro-inflammatory cytokines should play an important role in the chronic inflammation and increased cardiovascular risk of CRF patients on dialysis.	17190649
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	These data suggest that a low-grade inflammation of the intestinal wall is always present in CD and UC patients, which may predict a clinical relapse risk.	17190742
Inflammation of mucosa of intestine, Ulcerative Colitis, Precocious	Altered Intercellular Communication	The more precocious detectability of fecal calprotectin in CD patients, as a marker of intestinal mucosa inflammation, may be related to the different histopathology of the two diseases (CD versus UC).	17190742
Kidney Diseases	Altered Intercellular Communication	Severity of tubulointerstitial inflammation and prognosis in immunoglobulin A nephropathy.	17191083
Arteriolosclerosis, MPV17 gene, Interstitial inflammation, Tubular atrophy	Altered Intercellular Communication	Glomerulosclerosis, tubular atrophy, interstitial inflammation, and hyaline arteriolosclerosis correlated with progression in all patients and also in patients with initially normal serum creatinine.	17191083
Renal function, IGA Glomerulonephritis	Altered Intercellular Communication	We found parameters reflecting tubulointerstitial inflammation to predict deterioration of renal function in IgAN.	17191083
IGA Glomerulonephritis	Altered Intercellular Communication	Our findings show that, an immunohistochemical evaluation of tubulointerstitial inflammation seems to be a useful tool in determining the prognosis in IgAN.	17191083
Cholecystitis	Altered Intercellular Communication	Patients with gallbladder inflammation that underwent laparoscopy had an increased percentage of specifically bound IGFBP-3 to SNA compared with healthy subjects.	17191668
Cholecystitis	Altered Intercellular Communication	Our conclusion is that open surgery decreased the level of IGFBP-3 compared with laparoscopy, whereas patients with gallbladder inflammation that underwent laparoscopy had an increased content of sialic acid in IGFBP-3.	17191668
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Inflammation plays a critical role in acute myocardial infarction (MI).	17194712
Inflammation, Endothelial dysfunction, Diabetes Mellitus	Altered Intercellular Communication	An inverse association was found between sTM and type 2 diabetes risk after multivariable adjustment for diabetes risk factors, including several other markers of inflammation and endothelial dysfunction.	17195062
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Markers of inflammation and endothelial dysfunction were particularly strong confounders of the observed association.	17195062
Refractory anemias, Inflammation	Altered Intercellular Communication	It has been suggested that high serum levels of mannose-binding lectin (MBL) and agalactosyl IgG (IgG-G0) are associated with increased inflammation in RA.	17195187
hearing impairment, Inflammation, Sinusitis	Altered Intercellular Communication	We present the rare case of a patient whose hearing loss associated with inflammation of the inner ear and chronic sinusitis were improved with topical steroid therapy.	17195427
Inflammation, Sinusitis, Scleritis	Altered Intercellular Communication	A 68-year-old male presented with scleritis in the left eye, inflammation of the inner ear and chronic sinusitis.	17195427
Inflammation, Hepatitis C	Altered Intercellular Communication	HCV infection in the elderly entails higher inflammation activity and incidence of HCV RNA.	17195525
Refractory anemias, Inflammation	Altered Intercellular Communication	A significantl rise (p < 0.05) in content of middle mass molecules in the serum was found in all RA patients including in the disease onset and in minimal activity of inflammation and presence of only mono-olygoarthritis of the knee joints.	17195530
Inflammation, Hepatitis C Virus-Related Hepatocellular Carcinoma	Altered Intercellular Communication	Predictive power of biomarkers of oxidative stress and inflammation in patients with hepatitis C virus-associated hepatocellular carcinoma.	17195915
Inflammatory abnormality of the eye	Altered Intercellular Communication	Systematic screening for syphilis should be performed in unexplained ocular inflammation.	17196351
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Airway inflammation plays a role in the pathogenesis of chronic obstructive pulmonary disease (COPD).	17196413
Airway structure, Inflammation, ARCN1 gene	Altered Intercellular Communication	Endogenous hydrogen sulfide (H2S) is involved in the physiological and pathophysiological process in systemic inflammation and may be involved in the pathogenesis of airway inflammation and airflow obstruction in COPD.	17196413
Ileal adenocarcinoma, Crohn Disease, Inflammation	Altered Intercellular Communication	Three had surgery (Group A) and Crohn's disease was confirmed in two; the remainder had ileal adenocarcinoma in a pathological context of chronic inflammation.	17196893
Inflammation, Fibrosis Assessment, Endometriosis	Altered Intercellular Communication	While laparoscopic treatment is useful in endometriosis, it may fail in the presence of chronic inflammation and severe fibrosis.	17197355
Gallstone acute pancreatitis, Inflammation	Altered Intercellular Communication	To test the hypothesis that early endoscopic intervention, performed on patients with acute gallstone pancreatitis and biliopancreatic obstruction, reduces systemic and local inflammation.	17197959
Inflammation, Gallstone acute pancreatitis	Altered Intercellular Communication	The present study failed to provide evidence that early endoscopic intervention reduces systemic and local inflammation in patients with acute gallstone pancreatitis and biliopancreatic obstruction.	17197959
Inflammation, Perforation (observation)	Altered Intercellular Communication	Inflammation and perforation of a solitary diverticulum of the cecum.	17198478
Inflammation, Hemorrhage, Perforation (observation)	Altered Intercellular Communication	They are usually asymptomatic, and manifest clinically only with complications such as inflammation, perforation, or bleeding.	17198478
Inflammation, Perforation (observation), Cecal Diverticulum	Altered Intercellular Communication	We report on 5 cases of inflammation and perforation of a solitary cecal diverticulum, and perform a literature review.	17198478
Inflammation, Coronary Arteriosclerosis, Metabolic Syndrome X	Altered Intercellular Communication	Associations of serum uric acid with markers of inflammation, metabolic syndrome, and subclinical coronary atherosclerosis.	17198917
Inflammation, SLC25A20 gene, Metabolic Syndrome X, Coronary heart disease, Choline Dehydrogenase, Mitochondrial, MS gene	Altered Intercellular Communication	We examined the associations of serum uric acid (UA) with indices of coronary heart disease (CHD) risk, including the 10-year probability of CHD (10y-CHDr), metabolic syndrome (MS), inflammation (C-reactive protein [CRP] and fibrinogen), and the presence and quantity of coronary artery calcium (CAC).	17198917
Inflammation, Kidney Diseases	Altered Intercellular Communication	Disturbances in hemostasis and inflammation are common complications of kidney diseases.	17198929
HD Term Type, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Markers of endothelial dysfunction and inflammation were significantly elevated in HD patients compared with controls.	17198929
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	In CHD patients, serum albumin concentration is defined by a complex interaction of inflammation, nutrition, and dialysis efficacy.	17198937
Inflammation, Dental Plaque	Altered Intercellular Communication	Assessment of oral hygiene and gingival inflammation in albinos by the Silness and Loe plaque index and Loe and Silness gingival index, respectively, was unremarkable compared to control groups.	17199540
HD Term Type	Altered Intercellular Communication	The purpose of this study is to investigate the potential correlation between increased oxidative stress/inflammation and telomerase activity in PBMC of HD patients.	17199788
Communicable Diseases, Stomach Carcinoma, Inflammation	Altered Intercellular Communication	(1) Hp infection induces the overexpression of COX-2 and PPAR-gamma in the inflammatory and glandular cells within gastric mucosa, thus participating in the pathogenesis of gastric cancer (2) The expression of COX-2 induces by Hp is related to acute inflammation caused by Hp infection.	17199977
Inflammation, Electrocardiogram: myocardial infarction (finding), Depressive disorder	Altered Intercellular Communication	Lower levels of long-chain omega-3 polyunsaturated fatty acids (n-3 LCPUFAs) and increased inflammation have been associated with both depressive disorder and myocardial infarction (MI).	17201864
Inflammation, Depressed mood	Altered Intercellular Communication	Depressed post-MI patients had lower levels of n-3 LCPUFAs as measured by mean AA/EPA ratio and no signs of increased inflammation as determined by CRP levels.	17201864
Inflammation, Endoleak	Altered Intercellular Communication	The presence of inflammation and endoleak may predispose to further aneurysmal degeneration.	17202096
Delirium, Communicable Diseases	Altered Intercellular Communication	Delirium frequently occurs in the context of infection and other inflammatory conditions associated with elevated levels of cytokines.	17203511
Intestinal metaplasia, Inflammation, Dysplasia, Barrett Esophagus	Altered Intercellular Communication	Biopsies showed prominent intestinal metaplasia of Barrett's type without dysplasia, chronic inflammation and multiple aggregates of large cells within the mucosal lamina propria, some with spindle shaped nuclei.	17203537
Intestinal metaplasia, Inflammation, Peptic Esophagitis	Altered Intercellular Communication	The background of chronic inflammation with intestinal type metaplasia was consistent with long-term reflux esophagitis.	17203537
Inflammation, Helicobacter-associated gastritis	Altered Intercellular Communication	Usefulness of serum pepsinogens in Helicobacter pylori chronic gastritis: relationship with inflammation, activity, and density of the bacterium.	17203556
Inflammation	Altered Intercellular Communication	Serum levels of pepsinogens (sPG) were significantly correlated with H. pylori density both of the corpus (sPGI: r = 0.32, P < .001; sPGII: r = 0.56, P < .001) and antrum (sPGI: r = 0.41, P < .001; sPGII: r = 0.43, P < .001) as well as with chronic inflammation (sPGI: r = 0.26, P < .001; sPGII: r = 0.49, P < .001) and activity (sPGI: r = 0.38, P < .001; sPGII: r = 0.50, P < .001) in the antrum.	17203556
Inflammation	Altered Intercellular Communication	Only sPGII was correlated with chronic inflammation (r = 0.44, P < .001) and activity (r = 0.40, P < .001) in the corpus.	17203556
Gastritis	Altered Intercellular Communication	sPGII levels could be considered as markers of gastric inflammation all over in the stomach.	17203556
Inflammation	Altered Intercellular Communication	Autopsy case of neuro-Behcet's disease with multifocal neutrophilic perivascular inflammation.	17203596
Inflammation, Neurologic Deficits	Altered Intercellular Communication	These histopathological findings suggest that a destructive multifocal neutrophilic inflammation might have caused the neurological deficits.	17203596
Inflammation	Altered Intercellular Communication	Perivascular inflammation might be important to understanding the pathogenesis of neuro-Behcet's disease.	17203596
Inflammation, Occupational, Rhinitis	Altered Intercellular Communication	The objective of the present study was to examine nasal indices of inflammation in relation to occupational dust exposure, occupational rhinitis according to defined criteria, rhinitis symptoms associated to the workplace, and occupational sensitization in bakery-workers.	17204034
Eosinophilic disorder, Inflammation	Altered Intercellular Communication	We conclude that occupational dust exposure in bakery-workers is associated with nasal eosinophilic exudative inflammation.	17204034
Inflammation	Altered Intercellular Communication	In contrast, occupational sensitization is not a discriminating factor with regard to indices of eosinophilic, exudative inflammation in the present material.	17204034
Keratosis lichenoides chronica	Altered Intercellular Communication	Case of keratosis lichenoides chronica with atypical sarcoidal granulomatous inflammation.	17204100
Pain Distress Question	Altered Intercellular Communication	Patients with inflammatory MSC had higher pain scores than those with non-inflammatory conditions.	17204565
Autoimmune Diseases, Communicable Diseases, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	(18)F-FDG accumulates in malignant tissues but also at the sites of infection and inflammation and in autoimmune and granulomatous diseases by the overexpression of distinct facultative glucose transporter (GLUT) isotypes (mainly GLUT-1 and GLUT-3) and by an overproduction of glycolytic enzymes in cancer cells and inflammatory cells.	17204697
Kidney Failure, Chronic, Inflammation, Metabolic Diseases	Altered Intercellular Communication	Inflammation is a highly prevalent condition among end-stage renal disease (ESRD) patients and it has been implicated with several metabolic derangements.	17205966
Inflammatory Bowel Diseases, Colitis	Altered Intercellular Communication	Long-standing colonic inflammation is associated with a low prevalence of diverticuli in inflammatory bowel disease patients.	17206677
Inflammatory Bowel Diseases, Colitis	Altered Intercellular Communication	Long-standing colonic inflammation in IBD patients is associated with a lower prevalence of diverticuli.	17206677
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Two of the efflux transporters of importance for the barrier function of the gut mucosa, Pgp and BCRP, are expressed at strongly reduced levels during active inflammation in patients with UC.	17206689
Pouchitis, Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Recent clinical trials suggest the beneficial use of probiotics in the control of intestinal inflammation in pouchitis and ulcerative colitis.	17206696
Crohn Disease, Enteritis	Altered Intercellular Communication	We evaluated the utility of labeled leukocytes to detect small bowel inflammation and disease complications in Crohn's disease and compared it to whole small bowel enteroscopy and laparotomy findings.	17206712
Crohn Disease, Enteritis	Altered Intercellular Communication	In patients with Crohn's disease and small bowel inflammation seen at enteroscopy and/or laparotomy (n = 39) the scan was positive in 33.	17206712
Inflammation	Altered Intercellular Communication	In 8 patients without macroscopic small bowel inflammation, the scan was positive for the small bowel in 3 patients; at histology, 2 of 3 had inflammation.	17206712
Crohn Disease, Enteritis	Altered Intercellular Communication	Leukocyte scintigraphy reliably detects small bowel inflammation in Crohn's disease.	17206712
Psoriatic Juvenile Idiopathic Arthritis, Inflammation, Psoriasis	Altered Intercellular Communication	Significant overexpression of VAP-1 in both lesional and non-lesional psoriatic skin and higher serum level of soluble VAP-1 in psoriatic patients may indicate the role of VAP-1 in chronic inflammation occurring in psoriasis.	17207171
Interstitial inflammation	Altered Intercellular Communication	JK mm grafts had more interstitial inflammation than JK m grafts (p = 0.0369).	17207227
Inflammation, Rheumatoid Arthritis, Arthritis, Psoriatic	Altered Intercellular Communication	Synovial inflammation in active rheumatoid arthritis and psoriatic arthritis facilitates trapping of a variety of oral bacterial DNAs.	17207381
Refractory anemias, Inflammation, PROS1 gene, Arthropathy	Altered Intercellular Communication	These findings indicate that synovial inflammation in RA and PsA may favor trapping of oral bacterial DNAs, suggesting a perpetuating effect of oral pathogens in joint disease.	17207381
Inflammation, Atherosclerosis	Altered Intercellular Communication	Activation of immune cells such as monocytes initiates inflammation, a key step in atherosclerosis.	17209178
Allergic asthma, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Dendritic cells (DC) mediate inflammation in rodent models of allergic airway disease, but the role played by human respiratory-tract DC (hRTDC) in atopic asthma remains poorly defined.	17210044
Ancriviroc, Hepatic inflammation, Hepatitis C	Altered Intercellular Communication	In conclusion, this study showed that hepatic oxidatively generated DNA damage frequently occurs and is strongly associated with increased iron deposition and hepatic inflammation in CH-C patients, suggesting that iron overload is an important mediator of hepatic oxidative stress and disease progression in chronic HCV infection.	17210448
Inflammation	Altered Intercellular Communication	Cystatin C is a marker of kidney function that may also be associated with inflammation.	17210589
Inflammation, Renal function	Altered Intercellular Communication	Although a gold standard of kidney function is lacking, this analysis suggests that cystatin C captures an association of mildly impaired kidney function with increased inflammation.	17210589
Refractory anemias, Inflammation	Altered Intercellular Communication	The chronic inflammation of RA has been associated with oxidative stress, which is shown to cause a decline in the levels of cellular antioxidant sulfhydryls (R-SH).	17210617
Inflammation, Burn injury	Altered Intercellular Communication	However, the systemic inflammation associated with injury may limit the utility of CPIS in patients with burns.	17211204
Inflammation, Malnutrition, Sepsis, Cardiac complication, Cessation of life, Intoxication	Altered Intercellular Communication	The main causes of death were related to uraemic intoxication, malnutrition and inflammation as well as lack of permanent vascular access, all of it leading to sepsis, and cardiovascular complications.	17211289
Inflammation, HMOX1 gene	Altered Intercellular Communication	Higher levels of Hsp32, Hsp70 and Hsp90 were noticed in patients with inflammation, a commonly occurring natural stimulant of Hsp production, compared to control subjects.	17211576
Uremia, Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	In uremic patients, leptin in plasma serum was assumed to be associated with malnutrition, inflammation and atherosclerosis.	17211816
Inflammation	Altered Intercellular Communication	Isoelectric focusing is superior to immunofixation electrophoresis in diagnosing CNS inflammation.	17212616
Inflammation, Appendicitis, CTCAE, Gangrene	Altered Intercellular Communication	Two patients had features masquerading as appendicitis; one had perforated MD with secondary inflammation of the appendix, and the other had a torsed, gangrenous MD.	17212886
Inflammation, Coronary heart disease, Cerebrovascular accident	Altered Intercellular Communication	Recently, markers of inflammation, haemostasis, and blood rheology have received much attention as risk factors for coronary heart disease and stroke.	17213229
Neoplasms	Altered Intercellular Communication	We believe that ovarian-type stroma occurs in extragenital tumours as a result of an epithelial-stromal interaction in an environment of hormonal hyperstimulation.	17213356
Inflammation, Neurosarcoidosis	Altered Intercellular Communication	Right temporal lobe biopsy revealed noncaseating granulomatous inflammation consistent with neurosarcoidosis.	17213430
Inflammation, COL4A2 wt Allele, Cerebrovascular system, Cutaneous Small Vessel Vasculitis, Infarction	Altered Intercellular Communication	ICH may predispose certain patients to the development of infarcts through a combination of mechanisms, including mechanical compression of cerebral vessels, hemodynamic instability, inflammation and concomitant small-vessel pathology.	17213720
Inflammation	Altered Intercellular Communication	Because the Th response is associated with inflammation, the non-functional CC chemokine receptor 5 (CCR5) may rely in a less severe inflammatory state.	17214851
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor (TNF) is critical to regulation of inflammation.	17216494
Refractory anemias, Inflammation, Hyperplasia	Altered Intercellular Communication	Overexpression of VEGF-C in FLS by stimulation with TNF-alpha may play an important role in the progression of synovial inflammation and hyperplasia in RA by contributing to local lymphangiogenesis and angiogenesis.	17216674
Inflammation, Caseous necrosis	Altered Intercellular Communication	Intraoperative specimens were referred for histopathologic and microbiologic examination, which proved the existence of granulomatous inflammation of the areas with caseous necrosis.	17217110
Communicable Diseases, RGMA gene, Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation was found in 88.9% of biopsied tissue associated with M. marinum infection, 31.8% with RGM and 25.0% with MAC.	17217137
Inflammation	Altered Intercellular Communication	Identification of a novel CD160+ CD4+ T-lymphocyte subset in the skin: a possible role for CD160 in skin inflammation.	17218942
Dermatitis	Altered Intercellular Communication	Thus, we hypothesize that the unique CD4+ CD160+ lymphocyte subset plays a role in the pathogenesis of skin inflammation.	17218942
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Oxidative stress (OS), inflammation and insulin resistance are among the mechanisms that have been recently implicated in pathogenesis of essential hypertension (EH).	17220028
Inflammation	Altered Intercellular Communication	Peripheral polymorphonuclear leukocytes (PMNLs) are primed in EH patients, releasing uncontrolled superoxide anion contributing to OS and chronic low-grade inflammation in these patients.	17220028
Inflammation, Carcinogenesis	Altered Intercellular Communication	Cyclo-oxygenase (COX)-2 is not usually detectable in normal tissues but is induced in inflammation and carcinogenesis.	17220580
Inflammation, Atrophic	Altered Intercellular Communication	Histopathologic analysis of levator tissues revealed no significant difference in atrophy or degree of inflammation between experimental and control groups.	17220825
Guillain-Barre Syndrome, Familial, Inflammation, Traumatic injury	Altered Intercellular Communication	We believe that GBS was triggered by the trauma that evoked an immune mediated disorder producing inflammation and demyelination of the peripheral nerves.	17221022
Hypernatremia, Inflammation, Hyperparathyroidism, Hyperhomocysteinemia, HD Term Type, Diabetes Mellitus, Electrocardiogram: left ventricle hypertrophy (finding), Hypertension, CTCAE	Altered Intercellular Communication	They were evaluated for: age, sex, smoking, diabetes, hypertension, left ventricular hypertrophy, secondary hyperparathyroidism (SHP), inflammation, as evidence by elevated level of hsCRP, hyperhomocysteinemia (HOC), time on HD, fluid overload and adequacy of HD.	17221285
Barrett Esophagus, Inflammation	Altered Intercellular Communication	Active and chronic inflammation were significantly different between squamous epithelium and Barrett's metaplasia (P < 0.0001), but not during further progression in the sequence.	17222248
Coronary artery ectasia, Inflammation	Altered Intercellular Communication	Is any link between inflammation and coronary artery ectasia?	17222519
Inflammation, Atherosclerosis	Altered Intercellular Communication	Emerging investigations have pinpointed inflammation as a central process in all stages of atherosclerosis.	17222519
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Because aeroallergens produce inflammation in the respiratory airways, and inflammation triggers depression in vulnerable individuals, we hypothesized that mood sensitivity to pollen, the most seasonal aeroallergen, will be associated with a greater seasonality of mood.	17222915
Conjunctivitis, Structure of corneal epithelium	Altered Intercellular Communication	Twenty-four hours postoperatively, no significant differences between patching and "instant vision" could be found for corrected and uncorrected visual acuity, corneal epithelial defects, conjunctival inflammation, anterior chamber flare, and intraocular pressure (P > .05).	17223061
Pneumonitis	Altered Intercellular Communication	Alveolar macrophages (AMs) play a prominent role in influencing the development of lung inflammation and injury.	17223386
Orthodontic, Inflammation, Unknown (origin) (qualifier value), Traumatic injury	Altered Intercellular Communication	Etiologic factors include trauma, orthodontic treatment, intracoronal bleaching, and inflammation, but invasive cervical resorption is often idiopathic.	17223591
Inflammation	Altered Intercellular Communication	Serum levels of S100A12 reflect neutrophil activation during synovial inflammation.	17223658
Inflammation	Altered Intercellular Communication	These results suggest that the environment in crevices around titanium orthodontic anchor plates is anaerobic and supportive of anaerobic growth of bacteria, which may trigger inflammation in the tissue around the plates.	17224019
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Subjects with homozygosity for the minor S allele (S/S) of the G82S polymorphism had higher risk factors for cardiovascular disease, such as low sRAGE levels, inflammation, oxidative stress, and IR, compared with those bearing at least one G allele.	17224333
Acute inflammation, Traumatic injury	Altered Intercellular Communication	CME after phacoemulsification was associated with iris trauma and severe postoperative inflammation.	17224950
Inflammation	Altered Intercellular Communication	Except for a picture of chronic inflammation and a positive Anaplasma IgM antibody titre, serology yielded no indication ofthe diagnosis.	17225790
Interstitial inflammation	Altered Intercellular Communication	The chest X-ray, CT and lung biopsy demonstrated the presence of interstitial inflammation.	17226917
Inflammation, Albuminuria, Diabetes Mellitus, Non-Insulin-Dependent, macroangiopathy	Altered Intercellular Communication	Asymmetrical dimethylarginine is related to renal function, chronic inflammation and macroangiopathy in patients with Type 2 diabetes and albuminuria.	17227328
Renal Insufficiency, Inflammation, Albuminuria, Cardiovascular Diseases	Altered Intercellular Communication	Increased ADMA in T2DM patients with albuminuria is linked to cardiovascular disease and is associated with renal dysfunction and subclinical inflammation.	17227328
Inflammation	Altered Intercellular Communication	Changes in proinflammatory cytokine activity in psoriatic skin may play an important role in propagating inflammation.	17227730
Inflammation, Infection	Altered Intercellular Communication	Subjects with increased fat mass could be more susceptible to developing multiple infections resulting in a chronic low-grade inflammation.	17228053
Interstitial inflammation	Altered Intercellular Communication	Preserved leukocyte CD11b expression at the site of interstitial inflammation in patients with high-flux hemodiafiltration.	17228360
Interstitial inflammation	Altered Intercellular Communication	We have previously shown that in vivo transmigrated leukocytes from patients with low-flux bioincompatible hemodialysis have an impaired capacity to upregulate CD11b at the site of interstitial inflammation.	17228360
Interstitial inflammation	Altered Intercellular Communication	In patients, both monocytes and granulocytes had a preserved capacity to express CD11b following in vivo transmigration to sites of interstitial inflammation, compared with cells from healthy subjects.	17228360
Interstitial inflammation	Altered Intercellular Communication	Finally, leukocyte apoptosis in interstitial inflammation was similar in patients and healthy subjects.	17228360
Interstitial inflammation	Altered Intercellular Communication	We conclude that in vivo transmigrated leukocytes from patients on biocompatible high-flux hemodiafiltration or high-flux hemodialysis have a preserved capacity to express CD11b at the site of interstitial inflammation.	17228360
Inflammation, Pulpitis	Altered Intercellular Communication	The development of pulpitis is associated with elevated transcription of both Cu, Zn-SOD and Mn-SOD; pulp tissue inflammation generated higher Mn-SOD transcription compared with Cu, Zn-SOD.	17229118
Cataract, Intraocular inflammation, Traumatic, Congenital cataract	Altered Intercellular Communication	PEAK-fc is a very helpful cutting device for complicated cases of cataract surgery, especially for mature and congenital cataracts, traumatic zonulolysis or anterior segment complications after intraocular inflammation.	17229798
Intraocular inflammation	Altered Intercellular Communication	None of the eyes was found to have severe intraocular inflammation postoperatively.	17229801
Inflammation, Irritable Bowel Syndrome	Altered Intercellular Communication	In Irritable Bowel Syndrome, the gut-associated immune system may be up-regulated resulting in immune complex production, low-grade inflammation, loss of Class I bacteria, and translocation of inflammatory mediators and macromolecules outside of the GI lumen.	17229899
Inflammation	Altered Intercellular Communication	These results challenge the hypothesis that calcineurin-induced reduction of Treg or TGF-beta expression predisposes nontransplanted tissue to inflammation, but indicate that combined immunosuppression hampers Treg development in the intestine.	17230494
Sinusitis, Bronchiolitis, Eosinophilic inflammation	Altered Intercellular Communication	Eosinophilic bronchiolitis and eosionophilic sinusitis in this case may be considered to be a category of airway eosinophilic inflammation.	17233398
Inflammation, Carcinogenesis	Altered Intercellular Communication	During chronic inflammation, reactive nitrogen and oxygen species generated from inflammatory cells are considered to participate in carcinogenesis by causing DNA damage.	17233833
vascular inflammations	Altered Intercellular Communication	Increased circulating platelet-derived microparticles are associated with stent-induced vascular inflammation.	17234194
Inflammation, Restenosis	Altered Intercellular Communication	Inflammation as well as platelet activation at the site of local vessel-wall injury plays an essential role in the mechanism of restenosis after Percutaneous coronary intervention (PCI).	17234194
Inflammation, Pain Distress Question	Altered Intercellular Communication	The prostaglandins produced by COX-2 are involved in inflammation and pain response in different tissues in the body.	17234302
Inflammation, Data types - Address	Altered Intercellular Communication	It provided further evidence to support a role of inflammation in the development and progression of AD.	17234302
Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	Calprotectin (a major leucocyte protein) is strongly and independently correlated with joint inflammation and damage in rheumatoid arthritis.	17234650
Inflammation	Altered Intercellular Communication	Highly significant correlations (p<0.001) were also found between calprotectin and both laboratory and clinical markers of inflammation.	17234650
Asthma, Exacerbation, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Bronchial mucosal inflammation and upregulation of CXC chemoattractants and receptors in severe exacerbations of asthma.	17234659
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Lipoxygenases (LOX) are major enzymes that metabolize arachidonic acid to hydroxyl-eicosatetraenoic acids and leukotrienes, which have been implicated in inflammation and colorectal cancer risk.	17236225
Inflammation	Altered Intercellular Communication	Increased lean red meat intake does not elevate markers of oxidative stress and inflammation in humans.	17237312
Inflammation	Altered Intercellular Communication	It has been proposed that iron derived from red meat may increase iron stores and initiate oxidative damage and inflammation.	17237312
Helminthiasis	Altered Intercellular Communication	This novel regulatory mechanism of inflammation-related nutritional morbidity emphasizes the importance of treating prepubescent children for helminth infections.	17237323
Inflammation, Arthritis, Leucocytic infiltrate	Altered Intercellular Communication	From the studies on the experimentally induced arthritis in a transgenic mouse model that overexpresses a transcription factor, serum amyloid A activating factor-1 (SAF-1), leading to markedly higher levels of angiogenesis, synovial inflammation, and inflammatory cell infiltration, we have identified a novel mechanism of VEGF regulation.	17237427
Thrombosis	Altered Intercellular Communication	C-reactive protein (CRP) and serum amyloid A (SAA) increase in the blood of patients with inflammatory conditions and CRP-induced monocyte tissue factor (TF) may contribute to inflammation-associated thrombosis.	17237436
Rheumatoid Arthritis, Thrombosis, Inflammation	Altered Intercellular Communication	Elevated SAA is a marker of disease activity in patients with rheumatoid arthritis, and PBMC from patients with rheumatoid arthritis were more sensitive to SAA than normals, suggesting a new link between inflammation and thrombosis.	17237436
Thrombosis	Altered Intercellular Communication	C-reactive protein (CRP) and serum amyloid A (SAA) increase in the blood of patients with inflammatory conditions and CRP-induced monocyte tissue factor (TF) may contribute to inflammation-associated thrombosis.	17237436
Inflammation, Edema, Blepharoptosis	Altered Intercellular Communication	Topical cyclosporine and 1% methylprednisolone eliminated the anterior segment inflammation; subsequent treatment with systemic prednisone reduced the ptosis and edema.	17237695
Refractory anemias, Inflammation	Altered Intercellular Communication	TNF-alpha is a critical mediator of inflammation and metabolic response in patients with RA.	17237906
Inflammation, Atherosclerosis	Altered Intercellular Communication	Low-grade inflammation is a pathogenic factor for atherosclerosis.	17239709
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Diagnosis of H. pylori infection and its severity, histopathology, mucosal zinc concentration, and inflammation intensity were determined.	17241300
Inflammation	Altered Intercellular Communication	The degree of inflammation in H. pylori-induced gastritis appears to be modulated by gastric tissue zinc concentrations.	17241300
Inflammation, Hyperprostaglandinuria	Altered Intercellular Communication	The latter has been associated with chronic inflammation and hyperprostaglandinism.	17241478
Neurodegeneration due to 3-hydroxyisobutyryl coenzyme A hydrolase deficiency, Osteitis, Edema	Altered Intercellular Communication	Chronic bone oedema in adult HP and chronic hyper-prostaglandinism in childhood HP do suggest that in some HP patients bone inflammation is present in conjunction with the metabolic defect.	17241478
Inflammation	Altered Intercellular Communication	These cases illustrate chronic inflammation of the bone as a new feature of HP.	17241478
Burn Specimen Source Codes, Herpes zoster disease, Inflammation, Traumatic injury	Altered Intercellular Communication	Cutaneous lupus erythematosus is known to occur at sites of trauma or inflammation of the skin, including sites of tattoo, frostbite, herpes zoster scar, burn scar, and implantation by windshield glass.	17241591
Inflammation	Altered Intercellular Communication	No statistically significant differences were observed in most variables related to systemic inflammation or organ dysfunction/injury.	17242095
Inflammation, Atherosclerosis	Altered Intercellular Communication	Psychosocial factors and inflammation in the multi-ethnic study of atherosclerosis.	17242319
Inflammation, Peripheral Nervous System Diseases	Altered Intercellular Communication	Inducible costimulator, expressed by T lymphocytes, and inducible costimulator ligand, expressed by macrophages within the peripheral nerve, might not only be relevant in inducing an acute immune response but might also be critically involved in perpetuating inflammation in chronically immune-mediated disorders of the peripheral nervous system.	17242332
Inflammation, Fungal Colonization, Ulcer	Altered Intercellular Communication	1) Fungal colonization delays process of ulcer and inflammation healing of GI tract mucosa.	17242486
Adenocarcinoma, Inflammation	Altered Intercellular Communication	Chest radiography showed a nodule suggestive of adenocarcinoma in the middle lobe; however, transbronchial lung biopsy and computed tomography (CT)-guided percutaneous needle cytology showed signs of inflammation.	17243033
Thrombus, vascular inflammations, Hyperhomocysteinemia	Altered Intercellular Communication	The hypothesis that hyperhomocysteinemia increases arteriosclerotic or thrombotic risk through vascular inflammation was not supported by this study.	17243915
Uremia, Inflammation	Altered Intercellular Communication	Pregnancy-associated plasma protein A (PAPP-A) was recently described as a new marker of cardiovascular events and of inflammation in uremic patients.	17243917
Acute Coronary Syndrome, Inflammation	Altered Intercellular Communication	PAPP-A levels are elevated in acute coronary syndromes and are closely related to inflammation and oxidative stress.	17243917
Uremia, Inflammation, Osteodystrophy	Altered Intercellular Communication	We conclude that PAPP-A levels are increased in dialysis patients and may reflect a greater degree of chronic inflammation than osteodystrophy in uremic patients.	17243917
Inflammation, Rosacea	Altered Intercellular Communication	Recent evidence suggests that inflammation in rosacea is associated with generation of reactive oxygen species (ROS) that are released by inflammatory cells.	17244346
Inflammation, Rosacea, Abnormality of the vasculature, Chronic disease	Altered Intercellular Communication	Rosacea is a common chronic disease of unclear pathogenesis, characterised by inflammation and vascular abnormalities of the facial skin and ocular surface.	17244661
Colorectal Carcinoma	Altered Intercellular Communication	Evaluation of an inflammation-based prognostic score (GPS) in patients undergoing resection for colon and rectal cancer.	17245566
Granuloma, Inflammation, Venous Engorgement	Altered Intercellular Communication	Through operation and pathological examination, 8 cases had the granuloma formation of schistosomal eggs extensive surrounded by inflammation and venous congestion.	17249196
Hypothalamic Dysfunction Syndromes	Altered Intercellular Communication	Nevertheless, delayed hypothalamic dysfunction at the neurotransmitter level is the probable pathophysiological key factor.	17250734
Inflammation, Fibrosis Assessment, Asbestosis	Altered Intercellular Communication	Inhaled asbestos fibres can cause inflammation and fibrosis in the lungs called asbestosis.	17251310
Inflammation, Asbestosis	Altered Intercellular Communication	Measurement of exhaled NO at multiple exhalation flow rates and analysis of inflammatory markers in exhaled breath condensate are promising non-invasive means for assessing inflammation in patients with asbestosis.	17251310
Inflammation, Respiratory physiology	Altered Intercellular Communication	Systemic inflammation and decline in lung function in a general population: a prospective study.	17251312
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	An increase in levels of C-reactive protein (CRP), a marker of systemic inflammation, is associated with reduced forced expiratory volume in 1 s (FEV1), supporting the hypothesis that the pathophysiology of chronic obstructive pulmonary disease has a systemic inflammatory component.	17251312
melanoma, Granulomatous inflammation, Islet Cell Tumor, Renal Cell Carcinoma Pathway, Carcinoma of lung, Pheochromocytoma, Adenocarcinoma Of Esophagus	Altered Intercellular Communication	Diagnoses after EUS-FNA (the mean number of passes was 3.6) were: metastatic lung cancer (n = 2), esophageal adenocarcinoma (n = 1), melanoma (n = 1), renal cell carcinoma (n = 1), and pancreatic neuroendocrine tumor (n = 1); primary pheochromocytoma (n = 1); benign adrenal tissue (n = 21); and granulomatous inflammation (n = 1).	17252463
Inflammation, Cholelithiasis	Altered Intercellular Communication	Relaxation of the gallbladder and bile ducts emptying seem to be related to the reciprocal reflexes dampened by inflammation associated cholelithiasis.	17252989
Inflammation, Thrombosis, Blood Vessel	Altered Intercellular Communication	In portal areas, there was blood vessel congestion and thrombosis with inflammation.	17253054
Inflammation	Altered Intercellular Communication	A transbronchial biopsy revealed unspecific granulomatous inflammation of soft tissues.	17253210
Interstitial inflammation	Altered Intercellular Communication	The contribution of B cells to renal interstitial inflammation.	17255314
Interstitial inflammation	Altered Intercellular Communication	Furthermore, sites of chronic interstitial inflammation were associated with a high number of lymphatic vessels.	17255314
Primary malignant neoplasm, Colitis	Altered Intercellular Communication	Blood volume and blood flow each had a sensitivity of 80% and had specificity of 70% and 75%, respectively, for cancer in comparison with standard morphologic criteria: less than 5 cm of bowel involvement (45% sensitivity, 95% specificity), presence of a mass (85% sensitivity, 90% specificity), pericolonic inflammation (75% sensitivity, 5% specificity), and pericolonic nodes (90% sensitivity, 45% specificity).	17255417
GYPB gene, Sheehan Syndrome, Hypopituitarism	Altered Intercellular Communication	Initial hormonal levels indicated hypopituitarism, and magnetic resonance imaging led to diagnosis of empty sella in all patients, so that they were diagnosed as suffering from Sheehan's syndrome (SS).	17255644
Inflammation, Pancreatitis, Fibrosis Assessment	Altered Intercellular Communication	There was no evidence of pancreatitis (fibrosis or inflammation).	17255775
Inflammation, Atherosclerosis	Altered Intercellular Communication	This strengthens the association between periodontal inflammation and the presence of atherosclerosis.	17257161
Inflammation, Neoplasms, Ulcer, Rheumatoid Arthritis, Pyoderma Gangrenosum, Vasculitis, CTCAE, Anemia, Sickle Cell	Altered Intercellular Communication	In six patients with ulcers, the histology did not reveal any specific cause; five had a neoplasia, three had chronic inflammation, two had sickle cell disease, two had vasculitis, one had rheumatoid arthritis, one had pyoderma gangrenosum, and one had ulcer due to hydroxyurea.	17257802
Communicable Diseases, Inflammation	Altered Intercellular Communication	Sixty-three patients successfully retained their primary implant with rapid resolution of infection and inflammation.	17258811
Inflammation	Altered Intercellular Communication	It is unknown, however, whether systemic inflammation is correlated with non-culprit lesion inflammatory activation.	17258821
Inflammation	Altered Intercellular Communication	Local inflammatory activation in non-culprit lesions is correlated with systemic inflammation.	17258821
Inflammation	Altered Intercellular Communication	Severe septic inflammation as a strong stimulus of myocardial NT-pro brain natriuretic peptide release.	17258824
Heart Diseases, Inflammation	Altered Intercellular Communication	Eleven subjects without inflammation or cardiac disease served as controls.	17258824
Abnormal renal function, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation is associated with both chronic kidney dysfunction and type 2 diabetes.	17259488
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide (eNO) is a useful marker of eosinophilic airway inflammation in asthma patients.	17259808
Inflammation, Hepatic Encephalopathy	Altered Intercellular Communication	Role of ammonia and inflammation in minimal hepatic encephalopathy.	17260161
Hyperammonemia, Inflammation, Hepatobiliary Disorder	Altered Intercellular Communication	We evaluated whether the presence of MHE was associated with severity of liver disease, ammonia levels or the presence of inflammation and assessed factors determining neuropsychological deterioration accompanying induction of hyperammonemia.	17260161
Inflammation, Hepatobiliary Disorder	Altered Intercellular Communication	The presence and severity of MHE were independent of severity of liver disease and ammonia concentration but markers of inflammation were significantly higher in those with MHE compared with those without.	17260161
Inflammation, Hepatobiliary Disorder	Altered Intercellular Communication	This was independent of the magnitude of change in plasma ammonia and severity of liver disease but was significantly greater in those with more marked inflammation.	17260161
Inflammation	Altered Intercellular Communication	Our data show that inflammation is an important determinant of the presence and severity of MHE.	17260161
Hyperammonemia, Inflammation	Altered Intercellular Communication	The change in neuropsychological function following induced hyperammonemia is greater in those with more severe inflammation.	17260161
Psychiatric	Altered Intercellular Communication	Investigations into gastrointestinal, hormonal, and metabolic function were unremarkable, as was psychiatric evaluation.	17260810
Organizing inflammation, Mesenteric Panniculitis, Mesentery	Altered Intercellular Communication	Mesenteric panniculitis and sclerosing mesenteritis: a continuum of inflammation fibrosis.	17261382
Inflammation, Kidney Failure, Kidney Diseases, Diabetes Mellitus	Altered Intercellular Communication	Because renal failure per se is associated with both increased levels of circulating peptides and marked insulin resistance, even in the absence of diabetes mellitus, we hypothesized that visfatin could be a factor linking inflammation, kidney disease, and insulin resistance in this patient group.	17261426
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Inflammation may be associated with prostate cancer risk, but no environmental carcinogenic risk factors have been definitively identified.	17261765
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is a key component of atherosclerosis and inflammatory genes are good candidates for the risk of the development of atherosclerosis.	17261792
Inflammation, myocardial injury	Altered Intercellular Communication	Association of platelet-monocyte aggregates with platelet activation, systemic inflammation, and myocardial injury in patients with non-st elevation acute coronary syndromes.	17262778
Inflammation, myocardial injury	Altered Intercellular Communication	The interrelation of PMA with platelet activation, systemic inflammation, and their association with markers of myocardial injury has not been studied extensively.	17262778
Inflammation	Altered Intercellular Communication	Analysis of glycosylation profile revealed acute inflammatory process during episode of pseudocroup in the oldest children (over 5 years old) and chronic inflammation in group of the youngest children.	17263248
Inflammation, Malnutrition, Depression, CTCAE, Chronic Kidney Diseases	Altered Intercellular Communication	The authors suggest that the treatment modality, depression, malnutrition and inflammation have an important role on QoL in CKD.	17263698
Inflammation	Altered Intercellular Communication	Interleukin (IL) 19, IL-20 and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the regulation of epidermal functions and in inflammation.	17263806
Inflammation, Aneurysm	Altered Intercellular Communication	In the absence of any evidence of systemic inflammation in the form of elevated hs-CRP, these data support the hypothesis that aneurysms secrete IL-6 into the circulation.	17264016
Inflammation	Altered Intercellular Communication	After surgical resection, histopathological examination evidenced characteristic brownish fungal structures within granulomatous-purulent inflammation.	17264246
Inflammation, Atherosclerosis	Altered Intercellular Communication	Chronic inflammation and smoking have been individually associated with the development of atherosclerosis.	17264390
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Insulin resistance and erythrocyte sedimentation rate (ESR, a non-specific marker of inflammation) are known risk factors for cardiovascular disease.	17264953
Inflammation	Altered Intercellular Communication	TNF antagonists may block this TNF-dependent suppression of HO-1 expression, resulting in an amelioration of inflammation.	17265482
Inflammation	Altered Intercellular Communication	The biomarkers of inflammation decreased markedly when systematically analyzed (3 patients).	17265505
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To evaluate the sensitivity to change of power Doppler ultrasound (PDUS) assessment of joint inflammation and the predictive value of PDUS parameters in disease activity and radiologic outcome in patients with early rheumatoid arthritis (RA).	17266071
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	HLA-DRB1 and persistent chronic inflammation contribute to cardiovascular events and cardiovascular mortality in patients with rheumatoid arthritis.	17266100
Inflammation	Altered Intercellular Communication	CV mortality adjusted by age at disease onset and sex was associated with chronic inflammation determined by C-reactive protein level (CRP; hazard ratio [HR] 1.14, P < 0.001) and erythrocyte sedimentation rate (ESR; HR 1.05, P = 0.003).	17266100
Juvenile arthritis, Inflammation	Altered Intercellular Communication	In 50% of patients, JIA started with inflammation in one of the knees.	17266851
Refractory anemias, Coronary Arteriosclerosis, Metabolic Syndrome X	Altered Intercellular Communication	Inflammation-associated metabolic syndrome is a mechanism that may contribute to increased coronary-artery atherosclerosis in RA.	17266963
dendritic lamellar body	Altered Intercellular Communication	Damage to this network of structures in DLB may affect a number of different neurotransmitter systems which in turn may contribute to a number of the core clinical features of DLB.	17267521
Inflammation, Neoplasms	Altered Intercellular Communication	NKG2D ligands have been detected on many tumor cell types and can be induced on nontransformed cells by environmental signals including DNA damage and inflammation.	17267578
Inflammation, Neoplasms, Necrosis	Altered Intercellular Communication	Three of 7 patients underwent surgery, and stained sections of tumor were inspected for inflammation, necrosis, and scar tissue.	17268016
Inflammation, Ischemia	Altered Intercellular Communication	In 13 patients presenting with either acute or chronic coronary syndromes as indications for percutaneous coronary intervention, the following parameters were assessed: thermography, intravascular ultrasound (IVUS), angiography and serum markers for inflammation (C-reactive protein) and ischemia (troponin).	17268036
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Systemic markers of inflammation are considered reliable predictors of future coronary events in patients with acute myocardial infarction (AMI).	17268118
Inflammation, Veins	Altered Intercellular Communication	Vein graft harvesting induces inflammation of the graft wall.	17268886
Inflammation	Altered Intercellular Communication	In conclusion, surgical handling of vein grafts induces inflammation of the vessel wall.	17268886
Eye pain, Inflammation	Altered Intercellular Communication	The decentered intracorneal lens was removed due to ocular pain and inflammation, epithelial ingrowth under the corneal flap, and high order aberrations.	17269253
Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain and inflammation resolved, and corneal stability was regained > 6 months after removal of the lens.	17269253
Tissue Adhesions	Altered Intercellular Communication	Eight had surgery at 6 months of age or older, and of these, 4 (50%) had evidence of chronic inflammation/infection on histology including 1 case with multiple abscesses found at surgery and 1 case with multiple adhesions.	17270559
Anemia, Hereditary hemochromatosis, Thalassemia, Iron deficiency anemia	Altered Intercellular Communication	We obtained samples from healthy controls and patients with documented iron-deficiency anemia, inflammation-induced anemia, thalassemia major, and hereditary hemochromatosis.	17272487
Inflammation	Altered Intercellular Communication	Cholinergic signaling and acetylcholinesterase (AChE) influence immune response and inflammation.	17272501
Inflammation, Thymus Hyperplasia	Altered Intercellular Communication	MG is associated with thymic hyperplasia, showing signs of inflammation.	17272501
Inflammation, Cerebral Infarction, Antihypertensive Agents, Cerebrovascular accident	Altered Intercellular Communication	Low-grade inflammation is a risk factor for clinical stroke events in addition to silent cerebral infarcts in Japanese older hypertensives: the Jichi Medical School ABPM Study, wave 1.	17272770
Inflammation, Hypertensive (finding), Damage, Atherosclerosis	Altered Intercellular Communication	High-sensitivity C-reactive protein (hsCRP), a marker of inflammation, is associated with atherosclerosis, hypertensive target organ damage, and cardiovascular events.	17272770
Inflammation, Cerebral Infarction, Antihypertensive Agents, Cerebrovascular accident, Damage, Hypertensive (finding)	Altered Intercellular Communication	High-sensitivity C-reactive protein is a risk factor for clinical stroke events in addition to silent cerebral infarcts in Japanese older hypertensives, indicating that the risk for clinical stroke events increases with preexisting hypertensive target organ damage in the brain and additionally with ongoing low-grade inflammation.	17272770
ARCN1 gene, Inflammation	Altered Intercellular Communication	Furthermore, previous studies have shown that inflammation coexists in the nasal mucosa of patients with COPD.	17273748
ARCN1 gene, Inflammation	Altered Intercellular Communication	the lungs, despite the fact that inflammation coexists in the nasal mucosa of COPD patients.	17273748
Inflammation, Cholestasis, Necrosis	Altered Intercellular Communication	Liver function tests remained normal throughout the postoperative period; liver biopsy showed normal hepatic architecture with mild portal inflammation and cholestasis and spotty necrosis.	17275528
Inflammation	Altered Intercellular Communication	Inflammation might play a role in the growth of DS brains.	17275850
Inflammation, Myocardial dysfunction, Atherosclerosis	Altered Intercellular Communication	These findings support the role of inflammation and atherosclerosis in incipient myocardial dysfunction.	17276184
Intraocular inflammation, Malposition	Altered Intercellular Communication	The primary indication for IOL exchange was intraocular inflammation in patients with an AC IOL and IOL malposition in patients with a PC IOL.	17276266
Intraocular inflammation, Behcet Syndrome	Altered Intercellular Communication	In 17 eyes (13.0%), relapse of intraocular inflammation occurred within 6 months after surgery; the rate of relapse was highest in patients with Behcet's disease (35.2%).	17276275
Intraocular inflammation, Behcet Syndrome, Uveitis	Altered Intercellular Communication	Patients with Behcet's disease related to intraocular inflammation, however, appeared to have a higher risk for complications and therefore worse outcomes than patients with other clinical etiologies of uveitis.	17276275
Communicable Diseases, Inflammation, Immunocompromised Host, Leukopenia	Altered Intercellular Communication	We therefore compared the patterns of infection and inflammation among 3 cohorts of immunocompromised patients with profound neutropenia, nonneutropenic immunosuppression, and hematopoietic stem cell transplantation.	17276936
Hyperleucinemia, Inflammation, Peritonitis	Altered Intercellular Communication	Hyperleptinaemia and chronic inflammation after peritonitis predicts poor nutritional status and mortality in patients on peritoneal dialysis.	17277343
Hyperleucinemia, Inflammation, Peritonitis	Altered Intercellular Communication	We investigated the association between hyperleptinaemia, inflammation and malnourishment in PD-related peritonitis.	17277343
Inflammation, Peritonitis	Altered Intercellular Communication	Our study confirmed an increase in serum leptin during acute peritonitis and a prolonged course of systemic inflammation after apparent clinical remission of peritonitis.	17277343
Inflammation	Altered Intercellular Communication	These factors related to the persistent chronic inflammation may contribute to the development of malnourishment and poor survival rate.	17277343
Inflammation, Pouchitis, Ileitis, Ulcerative Colitis	Altered Intercellular Communication	We report a case of pouchitis and pre-pouch ileitis, and inflammation in the neo-terminal ileum proximal to the pouch, developed after restorative proctocolectomy for ulcerative colitis.	17278237
Panuveitis, Retinal Vasculitis, Hypopyon, Optic Neuritis	Altered Intercellular Communication	A few months later, he developed severe bilateral panuveitis with hypopyon, retinal vasculitis, and optic nerve inflammation.	17278947
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Improved endothelial function correlates better with reduced vascular fibrosis and inflammation markers than with vessel distensibility.	17278974
Necrotizing granulomatous inflammation	Altered Intercellular Communication	The pathologic report of the debridement of the right prosthetic knee was caseous granulomatous inflammation with positive acid-fast staining bacilli.	17282976
Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Increased expression of visfatin in macrophages of human unstable carotid and coronary atherosclerosis: possible role in inflammation and plaque destabilization.	17283255
Atherogenesis, Inflammation	Altered Intercellular Communication	Although the participation of inflammation in atherogenesis is widely recognized, the identification of the different components has not been clarified.	17283255
Inflammation, Dental Plaque	Altered Intercellular Communication	In particular, the role of inflammation in plaque destabilization is not fully understood.	17283255
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	C-reactive protein (CRP) elevated in inflammation is associated with atherosclerotic disease.	17283424
Inflammation	Altered Intercellular Communication	The sinus bone may be not in a static state, and remodeling occurs in response to chronic inflammation.	17283558
Restrictive lung disease, Inflammation, Periostitis, Pericarditis, CTCAE	Altered Intercellular Communication	Unexplained, transient inflammation seemed to cause her pericarditis, restrictive lung disease, and periostitis with accelerated skeletal turnover that responded well to antiinflammatory drugs and alendronate therapy.	17284635
Inflammation, Hemorrhage, Fibrosis Assessment, Squamous metaplasia	Altered Intercellular Communication	These alterations were squamous metaplasia (7 cases), acute and chronic hemorrhage and inflammation with multinucleated giant cells (26 cases) and granulation tissue with subsequent fibrosis (24 cases).	17285840
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Kidney Diseases	Altered Intercellular Communication	Association of low-grade inflammation with nephropathy in type 2 diabetic patients: role of elevated CRP-levels and 2 different gene-polymorphisms of proinflammatory cytokines.	17286233
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	An association between low -grade inflammation and type 2 diabetes has been described in some studies.	17286233
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Some authors suggest that increased serum resistin levels are associated with obesity, visceral fat, insulin resistance, type 2 diabetes and inflammation, while others failed to observe such correlations.	17287419
Inflammation	Altered Intercellular Communication	Visceral fat adipokine secretion is associated with systemic inflammation in obese humans.	17287468
Inflammation, Metabolic Diseases	Altered Intercellular Communication	Although excess visceral fat is associated with noninfectious inflammation, it is not clear whether visceral fat is simply associated with or actually causes metabolic disease in humans.	17287468
Inflammation, Obesity, Abdominal	Altered Intercellular Communication	These data suggest that visceral fat is an important site for IL-6 secretion and provide a potential mechanistic link between visceral fat and systemic inflammation in people with abdominal obesity.	17287468
Burn Specimen Source Codes, Liver damage, Inflammation	Altered Intercellular Communication	These data suggest that oxidative cellular damage correlates with burn severity and neuroendocrine system response modulates inflammation and oxidative cellular damage.	17287600
Burn Specimen Source Codes, Inflammation	Altered Intercellular Communication	Modulation of neuroendocrine system response and inflammation in the treatment in the early phase of burn may be useful to reduce the oxidative cellular damage and to prevent multiple organ failures in patients with extensive burn.	17287600
Inflammation	Altered Intercellular Communication	Since phagocytosis is host defenses attempt, the process indicates that mucin in the perimatrix is a cause of inflammation.	17287952
Autoimmune Diseases, Inflammation, Chagas Disease	Altered Intercellular Communication	Although autoimmunity may play a role in the pathogenesis of Chagas' disease, recent studies suggest a positive association of tissue parasitism, inflammation, and severity of lesions.	17288632
Neurodegenerative Disorders, Blood coagulation, Inflammation	Altered Intercellular Communication	Blood coagulation factor XIII (FXIII) plays a role in inflammatory processes and a pathogenetic role of inflammation in neurodegenerative disorders has been proposed.	17288735
methyldopa, Inflammation, Age related macular degeneration	Altered Intercellular Communication	The proteasome mediates pathways associated with oxidative stress and inflammation, two pathogenic events correlated with age-related macular degeneration (AMD).	17289037
methyldopa, Inflammation	Altered Intercellular Communication	The novel observation of proteasome transformation may reflect retinal response to local inflammation or oxidative stress with AMD.	17289037
Inflammation	Altered Intercellular Communication	The global overdiagnosis was 21.9% and 25% when the otoscopy is hindered by the presence of cerumen or when the eardrums show inflammation alone.	17289358
Pain Distress Question, Avitaminosis, Federated States of Micronesia, Sleep disturbances, Fatigue	Altered Intercellular Communication	Fibromyalgia (FM) is characterized by diffuse pain, fatigue, and sleep disturbances; symptoms that resemble the adult growth hormone (GH) deficiency syndrome.	17289417
Inflammation	Altered Intercellular Communication	C-reactive protein (CRP) is a well-established inflammation marker associated with cardiovascular risk.	17290100
Bladder Neoplasm, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	NSAIDs may reduce development of bladder tumors by decreasing inflammation, inhibiting cycloxygenase-2, inhibiting proliferation and inducing apoptosis of cancer cells.	17290403
Inflammation	Altered Intercellular Communication	In all cases indicators of inflammation and immunological response parameters were analyzed during the active stage of the disease.	17290830
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Obesity and type 2 diabetes mellitus (T2DM) have been associated with a state of chronic low-grade inflammation.	17292721
TG gene, Inflammation, HD Term Type, Chronic Kidney Diseases	Altered Intercellular Communication	The analysis included plasma AOPP, TG, cholesterol, albumin and total protein, inflammation and oxidative stress markers from healthy subjects, non-dialyzed CKD, HD and CAPD patients.	17292872
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Weak to absent correlations were observed between AOPP and markers of inflammation and oxidative stress in CKD patients.	17292872
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Thus, AOPP is a questionable biomarker of oxidative stress and inflammation in CKD patients.	17292872
Pain Distress Question, Inflammatory abnormality of the eye	Altered Intercellular Communication	Besides pain relief and reduction of ocular inflammation it remains unclear whether this procedure can also be used to improve vision in eyes with visual potential.	17294377
Cataract, Acute inflammation	Altered Intercellular Communication	To determine characteristics and final visual and surgical outcomes of patients who experienced early onset postoperative inflammation after cataract surgery and their early and late complications.	17294379
Cataract, Acute inflammation	Altered Intercellular Communication	This is a prospective case series of 126 patients out of 1500 cases who underwent cataract surgery and experienced early onset postoperative inflammation during the first 2 weeks after cataract surgery.	17294379
Inflammation, Low Vision, Pain Distress Question, Reduced visual acuity, Anxiety, CTCAE 3.0	Altered Intercellular Communication	Early onset postoperative inflammation causes pain, decreased vision, and patient anxiety in the acute phase but neither decreases final visual acuity nor has any significant or permanent ocular sequels.	17294379
Orbital Pseudotumor	Altered Intercellular Communication	In both cases, ultrasonography demonstrated evidence of orbital inflammation and in one patient computed tomography scan was consistent with OC.	17294397
Inflammation, Chronic heart failure, Endothelial dysfunction, Coronary Artery Disease	Altered Intercellular Communication	[The degree of inflammation and endothelial dysfunction in treatment of chronic heart failure in patients with coronary artery disease].	17294877
Inflammation	Altered Intercellular Communication	However, all the clinical manifestations, acute or chronic, are characterized by strong inflammation.	17295680
Airway structure, ARCN1 gene, Exacerbation	Altered Intercellular Communication	Sputum induction (SI) is considered to be a safe tool for assessing airway inflammation in stable patients with COPD, but little is known about its safety during exacerbations.	17296644
ARCN1 gene, Inflammation	Altered Intercellular Communication	Six-minute walking-induced systemic inflammation and oxidative stress in muscle-wasted COPD patients.	17296645
ARCN1 gene, Inflammation, Muscular Atrophy	Altered Intercellular Communication	Systemic inflammation and oxidative stress are potential mechanisms for muscle wasting in COPD patients.	17296645
Inflammation, Muscular Atrophy	Altered Intercellular Communication	The correlation between systemic oxidative stress and the degree of muscle wasting supports a possible causal relation between systemic inflammation, oxidative stress, and muscle wasting.	17296645
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Liver histological sections were studied for the presence of steatosis, inflammation and fibrosis.	17297427
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Steatosis, inflammation and fibrosis were more common in alcoholics.	17297427
Inflammation, Fibrosis Assessment, Fatty degeneration, Tuberculosis	Altered Intercellular Communication	Tuberculosis was the second commonest risk factor, showed grade 2 to 3 steatosis however inflammation and fibrosis were significantly less in cases of tuberculosis.	17297427
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Ocular surface and intraocular inflammation are related in SS-I and rheumatoid arthritis patients.	17297622
Sjogrens Syndrome", Intraocular inflammation, Rheumatoid Arthritis, Refractory anemias	Altered Intercellular Communication	The purpose of this study is to evaluate the intraocular inflammation at a sub clinical level, in patients suffering from Sjogren's syndrome (SS-I) and Rheumatoid Arthritis (RA), to relate it with the ocular surface status and to verify the diagnostic performance of the method.	17297622
Tears body substance, Dryness (characteristic), Inflammatory abnormality of the eye	Altered Intercellular Communication	A Kowa 500F laser cell flare meter was utilized to quantify the aqueous cells and flare in vivo, ocular surface inflammation was graded by conjunctival cytology and dosage of serum albumin in tears, eye dryness was scored with Tear Function Index.	17297622
Refractory anemias, Dryness (characteristic), Inflammatory abnormality of the eye	Altered Intercellular Communication	A blood-aqueous barrier breakdown occurs either in SS-I and RA patients; the degree of the damage is related with ocular surface inflammation and dryness.	17297622
Inflammatory abnormality of the eye, Musculoskeletal Pain	Altered Intercellular Communication	We recommend the aqueous flare be analysed in those rheumatic patients where an ocular surface inflammation has been documented.	17297622
Mycosis Fungoides, Inflammation, Cutis Laxa	Altered Intercellular Communication	Granulomatous slack skin (GSS) is a rare variant of mycosis fungoides in which inflammation leads to elastolysis manifested by pendulous skin folds with a predilection for flexural areas.	17298108
ARCN1 gene, Inflammation	Altered Intercellular Communication	Chronic systemic inflammation is likely to play a role in ED in COPD; the role of TNF-alpha should be evaluated further.	17298458
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation has been extensively implicated in the pathogenesis of Alzheimer's disease (AD).	17299019
Inflammation, Metabolic Syndrome X, Dyslipidemias, Diabetes Mellitus, Obesity, Hypertension, CTCAE	Altered Intercellular Communication	Serum apolipoprotein B predicts dyslipidemia, metabolic syndrome and, in women, hypertension and diabetes, independent of markers of central obesity and inflammation.	17299378
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Elevated levels of inflammation and adhesion have been implicated in the pathogenesis of cardiovascular disease.	17299382
Inflammation, Blood Vessel	Altered Intercellular Communication	Biopsy of skin lesions revealed inflammation of the small vessel accompanied by vascular IgA deposition.	17299986
Carcinogenic Salt, Lesion, Inflammation	Altered Intercellular Communication	A positive anti-p53 staining, but without p53 mutations, was also detected in 30% of LS lesions, suggesting a p53 stabilization in response to inflammation and carcinogenic insult.	17300232
Inflammation, Hematological Disease	Altered Intercellular Communication	Subcutaneous neutrophilic inflammation seemed to be more common in patients with an underlying haematological disorder.	17300237
Inflammation	Altered Intercellular Communication	They appear to represent a continuum of one disease characterized by IL-1-mediated inflammation.	17300660
Airway structure, ARCN1 gene	Altered Intercellular Communication	Eosinophilic airway inflammation and exacerbations of COPD: a randomised controlled trial.	17301099
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease, Exacerbation	Altered Intercellular Communication	Evidence suggests that eosinophilic airway inflammation is important in the pathogenesis of severe chronic obstructive pulmonary disease (COPD) exacerbations.	17301099
Airway structure	Altered Intercellular Communication	The majority of this benefit was confined to patients with eosinophilic airway inflammation.	17301099
Airway structure	Altered Intercellular Communication	Out of 42 patients in the sputum group, 17 required regular oral corticosteroids to minimise eosinophilic airway inflammation.	17301099
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	A management strategy that aims to minimise eosinophilic airway inflammation, as well as symptoms, is associated with a reduction in severe exacerbations of chronic obstructive pulmonary disease.	17301099
Intraocular inflammation	Altered Intercellular Communication	It is associated with increasing age, subclinical intraocular inflammation, and grade 2 deformity.	17301116
Inflammation, Coronary heart disease	Altered Intercellular Communication	Evidence exists that coronary heart disease is influenced by anaerobic bacterial flora and gingival inflammation.	17301602
Inflammation, Gastrointestinal problem	Altered Intercellular Communication	Exposure of the fetal intestine to amniotic fluid can cause inflammation and damage, and significant gastrointestinal problems occur during the neonatal period after closure of the defect.	17301669
Inflammation, Psoriasis vulgaris	Altered Intercellular Communication	Disorders in keratinocyte proliferation, differentiation, inflammation and immune dysregulation are the major factors implicated in the pathogenesis of psoriasis vulgaris.	17302610
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	In women, postmenopausal oestrogen supplementation increases levels of systemic markers of inflammation, which are important predictors of coronary heart disease (CHD) risk.	17302874
Inflammation	Altered Intercellular Communication	Low numbers of regulatory T cells in common variable immunodeficiency: association with chronic inflammation in vivo.	17302902
Autoimmune Diseases, Inflammation, Bacterial Infections, Common Variable Immunodeficiency	Altered Intercellular Communication	Common variable immunodeficiency (CVID) is a heterogeneous syndrome characterized by defective immunoglobulin production and high frequency of bacterial infections, autoimmunity and manifestations of chronic inflammation.	17302902
Inflammation, Common Variable Immunodeficiency	Altered Intercellular Communication	We have demonstrated decreased proportions of Treg in CVID patients, particularly in those with signs of chronic inflammation.	17302902
Macular Edema, Cystoid, Acute inflammation	Altered Intercellular Communication	None of the patients developed cystoid macular edema on postoperative fluorescein angiography or postoperative inflammation.	17303061
Neurogenic Inflammation, Lymphadenopathy, Toxoplasmosis, Cerebral, Headache	Altered Intercellular Communication	Recurrent headache as the main symptom of acquired cerebral toxoplasmosis in nonhuman immunodeficiency virus-infected subjects with no lymphadenopathy: the parasite may be responsible for the neurogenic inflammation postulated as a cause of different types of headaches.	17303977
Inflammation, Vertigo, Headache, Psychiatric, Syncope (amphibian)	Altered Intercellular Communication	All these biochemical disturbances caused by the CNS T. gondii infection/inflammation may also be responsible for the relationship found between neurologic symptoms, such as headache, vertigo, and syncope observed in apparently immunocompetent children and adolescents, and physical and psychiatric symptoms in adulthood.	17303977
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	We recently reported increased arterial thickening and stiffening in patients with rheumatoid arthritis (RA) to which inflammation and increased bone resorption contributed.	17304655
Inflammation, Orbital mucormycosis	Altered Intercellular Communication	In cases where orbital mucormycosis is suspected, cure may be expected even by the local administration of Amphotericin B if the inflammation is localized in the anterior part of the orbit.	17305091
glycation, Intraamniotic Route of Administration, Inflammation	Altered Intercellular Communication	The receptor for advanced glycation end products (RAGE) system in women with intraamniotic infection and inflammation.	17306673
glycation, Inflammation	Altered Intercellular Communication	Receptor for advanced glycation end products (RAGE) is a multiligand cell-surface receptor part of the immunoglobulin superfamily with crucial roles in inflammation.	17306673
Inflammation, Intraamniotic Route of Administration	Altered Intercellular Communication	The S100A12/ENRAGE system is markedly upregulated in women with intra-amniotic infection and correlates with the degree of inflammation.	17306673
methyldopa, Inflammation, Dryness (characteristic)	Altered Intercellular Communication	Complement factor H polymorphism T1277C (tyrosine-402 --> histidine-402) is strongly associated with both dry and wet AMD and points to a possible role for inflammation in the pathogenesis of AMD.	17306880
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	A randomized trial of the effects of rosiglitazone and metformin on inflammation and subclinical atherosclerosis in patients with type 2 diabetes.	17307426
Celiac Disease, Gastrointestinal inflammation	Altered Intercellular Communication	Celiac disease, an intestinal inflammation driven by mucosal CD4+ T cells recognizing wheat gluten peptides in the context of disease-associated HLA-DQ molecules, is an ideal model to test the potential clinical use of these reagents.	17307878
Bone Diseases, Inflammation	Altered Intercellular Communication	The purpose of this study was to examine whether inflammation was related to bone disease.	17308255
Inflammation	Altered Intercellular Communication	Longer PN dependence was associated with inflammation and negatively with T-helper cells.	17308255
Inflammation, Chronic intestinal failure	Altered Intercellular Communication	These preliminary findings are hypothesis generating only but support an association of low calcium and longer duration of PN with inflammation in patients with intestinal failure.	17308255
HD Term Type, Inflammation	Altered Intercellular Communication	However, PLTP activity was not related to markers of inflammation or to survival of HD patients, even though it correlated with HDL-C.	17308375
Blindness, Keratitis, "Moorens ulcer	Altered Intercellular Communication	Mooren's ulcer is a rare, severe corneal autoimmune inflammation leading to blindness if treated insufficiently.	17309011
Inflammation, Cornea	Altered Intercellular Communication	High-dose systemic cyclosporin A (Sandimmun optoral) was shown to markedly reduce inflammation and stop corneal destruction.	17309011
Inflammation, Periodontal Diseases, Diabetes Mellitus	Altered Intercellular Communication	Relationship between markers of metabolic control and inflammation on severity of periodontal disease in patients with diabetes mellitus.	17309586
Inflammation, Periodontal Diseases, Diabetes Mellitus	Altered Intercellular Communication	The aim of this study was to investigate the relationship between markers of metabolic control and inflammation and periodontal disease parameters in patients with diabetes.	17309586
Inflammation, COL4A2 wt Allele, Hyperirritability, Infancy, Hereditary, Hyperostosis	Altered Intercellular Communication	Infantile cortical hyperostosis (ICH) is an inherited disorder characterized by hyperirritability, acute inflammation of soft tissues, and massive subperiosteal new bone formation.	17309652
temporal pain, Inflammation	Altered Intercellular Communication	Preoperatively, she did not have any temporal pain, and no signs of inflammation were detected serologically.	17310805
Inflammation	Altered Intercellular Communication	Light-emitting diode (LED) photomodulation increases dermal collagen and reduces inflammation.	17311276
Ancriviroc, Liver carcinoma, Hepatitis C, Chronic, FAM126A gene	Altered Intercellular Communication	Interferon (IFN) improves hepatic inflammation/fibrosis and reduces the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis C (CH-C).	17311612
Bacteremia, Inflammation, Subacute Bacterial Endocarditis	Altered Intercellular Communication	Bacteremia and infectious endocarditis caused by Streptococcus bovis may be related to the presence of inflammation or neoplastic lesions in the large intestine.	17311758
Airway structure, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	Ventilation heterogeneity is a major determinant of airway hyperresponsiveness in asthma, independent of airway inflammation.	17311839
Airway structure, Respiratory Hypersensitivity	Altered Intercellular Communication	Airway inflammation and ventilation heterogeneity have been separately shown to be associated with airway hyperresponsiveness.	17311839
Airway structure, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	Airway inflammation was measured in 40 subjects with asthma by exhaled nitric oxide, ventilation heterogeneity by multiple breath nitrogen washout and airway hyperresponsiveness by methacholine challenge.	17311839
Airway structure, Respiratory Hypersensitivity	Altered Intercellular Communication	At baseline, airway hyperresponsiveness was independently predicted by airway inflammation (partial r2 = 0.20, p<0.001) and ventilation heterogeneity (partial r2 = 0.39, p<0.001).	17311839
Airway structure, Respiratory Hypersensitivity	Altered Intercellular Communication	Inhaled corticosteroid treatment decreased airway inflammation (p = 0.002), ventilation heterogeneity (p = 0.009) and airway hyperresponsiveness (p<0.001).	17311839
Airway structure, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	Baseline ventilation heterogeneity is a strong predictor of airway hyperresponsiveness, independent of airway inflammation in subjects with asthma.	17311839
Pancreatitis, Acute, Inflammation	Altered Intercellular Communication	Extrapancreatic inflammation on abdominal computed tomography as an early predictor of disease severity in acute pancreatitis: evaluation of a new scoring system.	17312456
Pancreatitis, Acute, Pancreatitis	Altered Intercellular Communication	In patients with acute pancreatitis, extrapancreatic inflammation assessed by abdominal CT scan and quantified with the EPIC score allows accurate estimation of disease severity and mortality within 24 h of admission.	17312456
Inflammation, Prostatic Intraepithelial Neoplasias, Prostate carcinoma	Altered Intercellular Communication	Chronic inflammation is negatively associated with prostate cancer and high-grade prostatic intraepithelial neoplasia on needle biopsy.	17313610
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Tissue inflammation has been linked to cancer in several disease models.	17313610
Inflammation, Prostatic Intraepithelial Neoplasias, Prostate carcinoma, Structure of posterior cerebral artery	Altered Intercellular Communication	We tested the association between chronic inflammation and prostate cancer (PCa), as well as high-grade prostatic intraepithelial neoplasia (HGPIN), in prostatic needle biopsy specimens.	17313610
Inflammation, Prostate, Structure of posterior cerebral artery	Altered Intercellular Communication	Tissues from 4526 men, who underwent systematic ultrasound-guided sextant needle biopsies of the prostate, were classified in the following order as PCa, or HGPIN, or chronic inflammation or benign.	17313610
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	PCa was diagnosed in 1633 (36.1%), HGPIN in 535 (11.8%) and chronic inflammation in 347 (7.7%).	17313610
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Chronic inflammation conferred a protective effect from PCa: odds ratio (OR) = 0.20, 95% confidence interval (CI) = 0.15-0.28.	17313610
Inflammation	Altered Intercellular Communication	Chronic inflammation was also inversely associated with HGPIN: OR = 0.11, 95% CI = 0.05-0.22.	17313610
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Chronic inflammation is more frequent in the presence of benign histology than it is in the presence of PCa or HGPIN.	17313610
HSPG2 wt Allele, Herpes Zoster Ophthalmicus, Inflammation, Scleritis	Altered Intercellular Communication	Patterns of chronic ocular disease observed after the acute episode included: mild/moderate SJS, severe SJS, ocular surface failure (SJS-OSF), recurrent episodic inflammation (SJS-RI), scleritis (SJS-S) and progressive conjunctival cicatrisation resembling mucous membrane pemphigoid (SJS-MMP).	17314145
Inflammation, Herpes Zoster Ophthalmicus	Altered Intercellular Communication	Immunosuppressive therapy successfully controlled inflammation in 10/10 patients with SJS-MMP, SJS-RI or SJS-S. Ocular disease in SJS/TEN is not limited solely to the sequelae of the acute phase illness.	17314145
Herpes Zoster Ophthalmicus, Acute Disease	Altered Intercellular Communication	Patients and physicians need to know that ocular disease progression, due to surface failure and/or acute inflammatory conditions, may occur at variable periods following the acute disease episode.	17314145
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	[Haemostatic and inflammation markers in acute coronary syndromes and its relationship with adverse cardiovascular events].	17315612
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	These findings suggesting that in acute phase and in a follow-up of an ACS abnormal coagulation, inflammation and fibrinolysis markers had independent and direct relationship with cardiovascular adverse events.	17315612
Acute myocardial infarction, Inflammation, Dental Plaque, Blood Clot	Altered Intercellular Communication	Microcirculatory dysfunction during acute myocardial infarction is mediated by various mechanisms including inflammation, thrombus, or plaque embolization.	17315613
Mesenteric Panniculitis, Fibrosis Assessment, Inflammation, Necrosis	Altered Intercellular Communication	Mesenteric panniculitis is a rare disorder characterized by nonspecific inflammation and/or necrosis and/or fibrosis in the adipose tissue of the bowel mesentery.	17316921
Inflammatory abnormality of the eye	Altered Intercellular Communication	Four weeks after starting treatment his visual acuity improved with decrease in ocular inflammation.	17317410
Airway structure, Lung function testing abnormal, Craniosynostosis, Asthma, Chronic sinusitis, IL13 gene, Rhinitis	Altered Intercellular Communication	Our hypothesis is that in patients with symptoms of persistent rhinitis, lower airway inflammation, lower respiratory symptoms, and lung function abnormalities compatible with asthma are more frequently associated with the diagnosis of allergic rhinitis (AR) and chronic rhinosinusitis (CRS) than with nonallergic rhinitis (NAR).	17317733
Airway structure, Asthma, Craniosynostosis, Rhinitis	Altered Intercellular Communication	The diagnostic classification of persistent rhinitis helps to predict lower airway inflammation (increased Feno) and prevalence of asthma: AR and CRS are associated with higher mean Feno values and higher prevalence of asthma than NAR.	17317733
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histological examination disclosed various phases of inflammation and significant fibrosis.	17317942
Inflammation	Altered Intercellular Communication	Subsequently, progressive inflammation developed around the left implant and removal of the implant was necessary.	17319363
Inflammation, Breast problem, Pathology, Mastitis, Communicable Diseases, Abscess of breast, Stasis	Altered Intercellular Communication	Respondents perceived breast problems related to lactation to be highly prevalent and described a sequence of symptoms which resembles the biomedical understanding of pathologies related to breastfeeding, ranging from breast engorgement (stasis) to inflammation (mastitis) and infection (breast abscess).	17319940
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	In view of the fact that chokeberry flavonoids reduce the severity of inflammation, regardless of statins, they can be used clinically for secondary prevention of ischaemic heart disease.	17320090
Malignant Neoplasms	Altered Intercellular Communication	The perception and practice of traditional medicine in the treatment of cancers and inflammations by the Hausa and Fulani tribes of Northern Nigeria.	17320319
Inflammation, Premature coronary artery atherosclerosis	Altered Intercellular Communication	Matrix metalloproteinases in premature coronary atherosclerosis: influence of inhibitors, inflammation, and genetic polymorphisms.	17320799
Inflammation, Metabolic Diseases	Altered Intercellular Communication	In conclusion, MMP and TIMP plasma levels in premature CAD are linked to clinical presentation and markers of inflammation and metabolic disorders rather than to genetic polymorphisms.	17320799
Inflammation, Endophthalmitis, CTCAE	Altered Intercellular Communication	Endophthalmitis, an ophthalmic condition characterized by an inflammation of the intraocular cavity, can have substantial implications for vision.	17320963
Inflammation	Altered Intercellular Communication	Little is understood regarding the relationship of tissue IgE to systemic IgE, inflammation or clinical outcomes.	17321582
Inflammation, Exacerbation of asthma, MS4A2 wt Allele	Altered Intercellular Communication	To evaluate local IgE expression and cellular inflammation in the proximal and distal lung of normal subjects and subjects with asthma of varying severity and relate those tissue parameters to systemic IgE levels, atopy, lung function, and history of severe exacerbations of asthma.	17321582
Inflammation, MS4A2 wt Allele	Altered Intercellular Communication	Tissue expression of IgE, FcepsilonRIbeta, cellular inflammation, serum IgE, and atopy were compared.	17321582
Inflammation, Asthma	Altered Intercellular Communication	Local IgE appears to be primarily a component of responses within the mucosal immune compartment and is related to cellular inflammation, lung function, and clinical outcomes in asthma.	17321582
Chronic Infantile Neurological, Cutaneous, and Articular Syndrome, Inflammatory abnormality of the eye, Skin lesion, Ulceration, CTCAE, Behcet Syndrome	Altered Intercellular Communication	Behcet's disease (BD) is a multisystem inflammatory disease characterized by recurrent orogenital ulceration, ocular inflammation, and skin lesions.	17321902
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Inflammation was associated with morphological and clinical progression of atherosclerotic disease.	17322087
Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Steatohepatitis	Altered Intercellular Communication	Erythrophagocytosis by liver macrophages (Kupffer cells) promotes oxidative stress, inflammation, and fibrosis in a rabbit model of steatohepatitis: implications for the pathogenesis of human nonalcoholic steatohepatitis.	17322381
Corneal edema	Altered Intercellular Communication	Postoperative corneal edema occurred in 11 cases (33.3%) and anterior chamber inflammation was present in nine cases (27.3%).	17322465
Inflammation, Dystrophic calcification	Altered Intercellular Communication	Tonsillolith is a rare dystrophic calcification as a result of chronic inflammation of the tonsils.	17322801
Inflammation, Coronary heart disease	Altered Intercellular Communication	Several cross-sectional and cohort studies have reported an association between serum markers of inflammation such as C-reactive protein, and coronary heart disease in Caucasian populations.	17323825
Inflammation, Tooth Loss	Altered Intercellular Communication	These patients displayed minimal gingival inflammation and tooth loss during SPC.	17324157
Celiac Disease, Inflammation	Altered Intercellular Communication	Interleukin (IL)-15 delivers signals that drive chronic inflammation in several diseases, including celiac disease.	17324400
Celiac Disease, Gastrointestinal inflammation	Altered Intercellular Communication	Impairment of TGF-beta-mediated signaling by IL-15 might promote and sustain intestinal inflammation in celiac disease.	17324400
Inflammation, Ulcer	Altered Intercellular Communication	Ulcer size, inflammation, healing, visual acuity, and patient's subjective symptoms.	17324465
Inflammation, Pain Distress Question	Altered Intercellular Communication	Inflammation and subjective symptoms, particularly pain, improved in all patients.	17324465
Pain Distress Question, Corneal Perforation, Corneal Ulcer, Inflammation	Altered Intercellular Communication	Autologous platelet-rich plasma promoted healing of dormant corneal ulcers even in eyes threatened by corneal perforation and was accompanied by a reduction in pain and inflammation.	17324465
Inflammation, Panniculitis	Altered Intercellular Communication	The diagnosis and proper classification of panniculitis relies on histologic features, mainly the location of the subcutaneous inflammation (septal, lobular, mixed or vascular).	17324837
Inflammation, Erythema Nodosum	Altered Intercellular Communication	In contrast to erythema nodosum, where the inflammation predominates in the fat septa, NP is localized in the fat lobules.	17324837
Refractory anemias, Inflammation	Altered Intercellular Communication	Parallel to the severity of inflammation, END and ENK in immune cells and their receptors on sensory nerve terminals are more abundant in patients with RA than in those with JT and OA.	17324971
Inflammation, Pain Distress Question	Altered Intercellular Communication	These findings are consistent with the notion that, with prolonged and enhanced inflammation, the immune and peripheral nervous systems upregulate sensory nerves expressing ORs and their ligands to counterbalance pain and inflammation.	17324971
Inflammation, Coronary heart disease	Altered Intercellular Communication	Recent studies indicated that local inflammation played a pivotal role in the pathogenesis of coronary heart disease.	17326063
Inflammation	Altered Intercellular Communication	However, whether they can reflect local coronary inflammation is unclear.	17326063
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	We hypothesized that transcoronary concentration gradient of sCD40L could reflect local inflammation in patients with coronary heart disease (CHD) more reliably.	17326063
Inflammation, Dental Plaque, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	In patients with CHD, the transcoronary concentration gradient of sCD40L is more sensitive than hsCRP, and sCD40L possibly a better marker of local inflammation and plaque instability.	17326063
Inflammation, Atherosclerosis	Altered Intercellular Communication	Oxidized low-density lipoprotein (oxLDL), the antibodies against oxLDL and the lipoprotein-associated phospholipase A2 (Lp-PLA2) may play important roles in inflammation and atherosclerosis.	17326817
Inflammation, Calcinosis	Altered Intercellular Communication	The histological findings were: 1) fibroblastic tissue high cellularity (58.8%); 2) scarce odontogenic epithelium (64.7%); 3) inflammation (94.1%) and 4) absence of calcification (58.8%).	17327815
Refractory anemias, Inflammation	Altered Intercellular Communication	Despite the presence of these immunoregulatory cells in RA, chronic inflammation persists.	17328044
Refractory anemias, Inflammation	Altered Intercellular Communication	Our findings suggest that the interaction of CD4+,CD25+ Treg cells with activated monocytes in the joint might lead to diminished suppressive activity of CD4+,CD25+ Treg cells in vivo, thus contributing to the chronic inflammation in RA.	17328044
Arthritis, Orchitis	Altered Intercellular Communication	PAR-2 is known to exert proinflammatory actions in a murine model of arthritis, since PAR-2-deficient mice exhibit strikingly reduced articular inflammation.	17328048
Data types - Address, Dermatitis, Atopy	Altered Intercellular Communication	The recently recognized atopic nature of the skin inflammation in AD has raised a growing interest in the treatment with allergen-specific immunotherapy (SIT).	17328144
Dermatitis, Data types - Address, Respiratory allergy	Altered Intercellular Communication	It is concluded that SIT may be highly promising method of controlling skin inflammation in AD with the potential to prevent the development of AD into respiratory allergy.	17328144
Granulomatous inflammation, Asteroids	Altered Intercellular Communication	In our case, a lymph node aspirate showing asteroid bodies in a background of granulomatous inflammation supported the diagnosis.	17328498
Inflammation, Atherosclerosis	Altered Intercellular Communication	C-reactive protein (CRP) is not only an acute phase reactant but also a sensitive marker of subclinical inflammation associated with atherosclerosis.	17329914
Inflammation, Atherosclerosis	Altered Intercellular Communication	These results suggest that tight good glycemic control, even in very elderly subjects, may be able to reduce the systemic inflammation that contributes to leads to atherosclerosis.	17329914
Inflammation, Asthma	Altered Intercellular Communication	The peroxisome proliferator-activated receptor gamma (PPARgamma) regulates inflammation and may play a role in asthma.	17329993
Inflammation, Fatigue	Altered Intercellular Communication	Handgrip performance in relation to self-perceived fatigue, physical functioning and circulating IL-6 in elderly persons without inflammation.	17331228
Inflammation, Fatigue	Altered Intercellular Communication	Low grip strength is recognized as one of the characteristics of frailty, as are systemic inflammation and the sensation of fatigue.	17331228
Inflammation, Pathologic TNM Finding, Neoplasm Metastasis, Neoplasms, Infiltration	Altered Intercellular Communication	Histological study included pTNM classification, tumour size, surgical margins, extracapsular spread of lymph-node metastasis, perineural infiltration, peritumoral inflammation and bone involvement.	17331706
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Variants in genes related to inflammation contribute to risk of stroke.	17332449
Inflammation, Atrial Fibrillation by ECG Finding, Cerebrovascular accident	Altered Intercellular Communication	High-sensitivity C-reactive protein and soluble CD40 ligand as indices of inflammation and platelet activation in 880 patients with nonvalvular atrial fibrillation: relationship to stroke risk factors, stroke risk stratification schema, and prognosis.	17332453
Inflammation, Cerebrovascular accident, Cardiovascular Diseases	Altered Intercellular Communication	We tested the hypothesis that plasma levels of C-reactive protein (CRP; an index of inflammation) and soluble CD40 ligand (an index of platelet activation, with links to inflammation) could be related to 3 established stroke risk stratification schema (SPAF, CHADS(2), and NICE), recognized stroke risk factors or other cardiovascular disease, and prognosis.	17332453
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by chronic airway inflammation.	17332482
Communicable Diseases, Inflammation	Altered Intercellular Communication	99mTc-labeled interleukin 8 for the scintigraphic detection of infection and inflammation: first clinical evaluation.	17332609
Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	No erosive progression revealed by MRI in rheumatoid arthritis patients treated with etanercept, even in patients with persistent MRI and clinical signs of joint inflammation.	17332974
Refractory anemias, Inflammation	Altered Intercellular Communication	This small study supports that erosive progression judged by MRI is minimal in RA patients treated with etanercept, even in joints with persistent inflammation.	17332974
Acute cholangitis, Inflammation, Hepatitis E	Altered Intercellular Communication	Characteristic pathological signs of acute hepatitis E were severe intralobular necrosis, polymorph inflammation, and acute cholangitis with numerous neutrophils.	17333266
Asthma	Altered Intercellular Communication	Transforming growth factor beta-1 (TGFB1) may influence asthma by modulating allergic airway inflammation and airway remodeling.	17333284
Neoplasms	Altered Intercellular Communication	These findings suggest that inflammation-dependent tumors (Group A) may be derived from a highly restricted, probably H. pylori-associated, B cell subset and may not often progress to those that are inflammation-independent (Groups B and C).	17334352
Encephalomyelitis, Inflammation, Demyelination	Altered Intercellular Communication	Acute disseminated encephalomyelitis was documented in all cases by characteristics MRI changes included inflammation and demyelination in subcortical or periventricular regions.	17334467
Inflammation, Demyelination	Altered Intercellular Communication	We identified inflammation and demyelination in subcortical than periventricular lesions by magnetic resonance imaging.	17334467
Microalbuminuria, Inflammation, Hypertensive (finding), Hypertensive Retinopathy	Altered Intercellular Communication	Relationship of early hypertensive retinopathy to inflammation markers and microalbuminuria in hypertensive patients with regulated blood pressure.	17334487
Inflammation, Endothelial dysfunction, Intermittent Claudication	Altered Intercellular Communication	Ischemia/reperfusion damage evokes systemic inflammation and endothelial dysfunction in patients with intermittent claudication.	17334512
vascular inflammations, Thrombosis	Altered Intercellular Communication	APP have been viewed as indexes of active vascular inflammation or as mediators of atherothrombosis.	17335831
Inflammation, IL13 gene, MS4A2 wt Allele	Altered Intercellular Communication	These data support the hypothesis that in persistent nonallergic rhinitis some patients may have local inflammation, nasal IgE production, and a positive response to a nasal allergen provocation test despite no evidence of systemic atopy.	17337294
Inflammation, Malnutrition, Anemia, Cessation of life, Comorbidity	Altered Intercellular Communication	However, after adjusting for potential confounders (demographics, dialysis vintage, dose, comorbidity, anemia, and surrogates of malnutrition and inflammation), higher A1C values were incrementally associated with higher death risks.	17337501
Inflammation, Breast Carcinoma, Fibroadenoma, Cyst	Altered Intercellular Communication	Fibroadenoma, inflammation, and cysts did not exhibit an association with breast cancer development.	17337650
Inflammation, Ischemic stroke	Altered Intercellular Communication	The role of inflammation in the pathogenesis of acute ischemic stroke is well known, but its association with the clinical picture is as yet unclear.	17337911
Colonic Diverticulitis, Acute inflammation	Altered Intercellular Communication	Colonic diverticulitis represents an acute bowel inflammation, in many cases, confined only to the sigmoid and descending colon.	17338195
Inflammation, Appendicitis, CTCAE, Diverticulitis, Obstruction	Altered Intercellular Communication	It has been speculated that obstruction at the mouth of the diverticulum results in diverticulitis, similar to appendicitis, but this is no longer the accepted theory, and some feel that chronic inflammation precedes clinical diverticulitis.	17338195
Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Atrial fibrillation and plasma troponin I elevation after cardiac surgery: relation to inflammation-associated parameters.	17338744
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Recent studies have demonstrated correlation between inflammation to plasma troponin (cTnI) levels elevation and atrial fibrillation (AF) in noncardiac surgery settings.	17338744
Inflammation	Altered Intercellular Communication	The goal of this prospective study was to examine the relation between inflammation associated parameters (IAPs) to post cardiac surgery cTnI elevation and AF.	17338744
Inflammation, Muscle damage	Altered Intercellular Communication	This study was designed to address the question of whether an anterior MIS approach generates less inflammation and muscle damage than the standard posterolateral (PL) approach.	17338907
Inflammation, Actual blood loss, Muscle damage	Altered Intercellular Communication	No significant differences were found between the two approaches either in inflammation and muscle damage or blood loss.	17338907
Communicable Diseases, Leukemoid Reaction, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Leukemoid reaction is defined as a reactive leukocytosis in response to infection, inflammation, or therapeutic agents such as growth factors and malignancy.	17339172
allergic inflammation	Altered Intercellular Communication	Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine that strongly activates dendritic cells (DC) and can initiate allergic inflammation.	17339431
Inflammation, Age related macular degeneration, Retinal Pigments, Family history	Altered Intercellular Communication	Because the interaction of CRP and FH promotes complement-mediated clearance of cellular debris in a noninflammatory fashion, we propose that the reduced binding of FH(402H) to CRP could lead to an impaired targeting of FH to cellular debris and a reduction in debris clearance and enhanced inflammation along the macular retinal pigmented epithelium-choroid interface in individuals with age-related macular degeneration.	17339482
Inflammation	Altered Intercellular Communication	Based on recent observations we now hypothesize that a type I interferon-driven inflammation might be involved in the pathogenesis of this disease.	17340016
Hernia	Altered Intercellular Communication	Inflammation of the appendix determines the type of hernia repair and surgical approach.	17340052
Inflammation, Alopecia, CTCAE, Obesity	Altered Intercellular Communication	Obesity and low-grade inflammation among young Finnish men with early-onset alopecia.	17341860
Inflammation, Alopecia, CTCAE, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	To examine the possible association between early-onset alopecia and low-grade inflammation measured by high-sensitivity C-reactive protein (hs-CRP) that has been recommended for the assessment of the cardiovascular disease (CVD) risk.	17341860
Alopecia, CTCAE, Inflammation, Obesity, Abdominal	Altered Intercellular Communication	Our findings show a relation between moderate to extensive alopecia and low-grade inflammation--a predictor of a future CVD--especially combined with central obesity, among men younger than 35 years.	17341860
Hypogonadotropic hypogonadism	Altered Intercellular Communication	The hormonal assay was consistent with hypogonadotrophic hypogonadism.	17342298
Dystrophy, Keratitis, Corneal dystrophy	Altered Intercellular Communication	The aforesaid seem to confirm that Salzmann's nodular corneal dystrophy, corneal dystrophy is not induced by repeated inflammations but conversely, pathological metabolism of the cornea in consequence of dystrophy is responsible for serial keratitis.	17344169
Inflammation, Comorbidity, Anorexia	Altered Intercellular Communication	Finally, appetite loss was associated with worse clinical outcome even after adjustment for age, sex, inflammation, dialysis vintage, and comorbidity (likelihood ratio = 44.3; P < 0.0001).	17344489
Inflammation, Malnutrition	Altered Intercellular Communication	These results show a close association among appetite, malnutrition, inflammation, and outcome in patients undergoing prevalent hemodialysis.	17344489
Uremia, Anorexia	Altered Intercellular Communication	Moreover, our data suggest that uremic men may be more susceptible than are women to inflammation-induced anorexia.	17344489
Inflammation, Coronary Artery Disease, Atherosclerosis	Altered Intercellular Communication	Inflammation and atherosclerosis: the role of TNF and TNF receptors polymorphisms in coronary artery disease.	17346438
Inflammation, Acute Coronary Syndrome, Coronary Artery Disease, Atherosclerosis	Altered Intercellular Communication	Inflammation plays an important role in the pathogenesis of atherosclerosis and coronary syndromes; moreover, various lines of evidence suggest that genetic factors contribute significantly to the risk of coronary artery disease (CAD).	17346438
HD Term Type, Inflammation	Altered Intercellular Communication	We conclude that in HD patients, sRAGE is increased due to decreased renal function, which is a very strong determinant of sRAGE levels, and is inversely related to inflammation.	17347281
Inflammation, Malnutrition, Hyperparathyroidism, Secondary	Altered Intercellular Communication	Secondary hyperparathyroidism, malnutrition and inflammation have been reported to associate with adverse outcomes in dialysis patients.	17347578
Diverticular disease of colon, Ulcerative Colitis	Altered Intercellular Communication	Patients with ulcerative colitis show a significantly lower prevalence of colonic diverticulosis, with this finding probably reflecting the motor alterations caused by chronic bowel wall inflammation.	17347901
Bacteremia, Pneumonitis, Pneumonia	Altered Intercellular Communication	Mortality correlated with the development of pneumonia and lung inflammation but not with bacteremia.	17348295
Inflammation, Congestion, Disorder of eye, TAO brand of troleandomycin, Graves Disease	Altered Intercellular Communication	Thyroid-associated ophthalmopathy (TAO) is a common yet poorly understood component of Graves' disease involving inflammation, congestion and soft tissue remodelling of the orbit.	17349012
Inflammation, Hemorrhage, Neoplasms	Altered Intercellular Communication	Additional observations of marked perivascular and onionskin-like chronic inflammation and consistent hemorrhage may aid in the diagnosis of this previously well-described tumor.	17349565
Xanthogranulomatous inflammation, Endometriosis of pelvis, Endometriosis	Altered Intercellular Communication	Although it has been associated with pelvic endometriosis, it has never been demonstrated through progressive changes, beginning with mucosal endometriosis to the full-blown xanthogranulomatous inflammation.	17349571
Inflammation, Liver Failure	Altered Intercellular Communication	This study supports the hypothesis that septic liver failure is linked to the induction of NO synthesis in major systemic inflammation.	17349850
Inflammation, Dental Plaque	Altered Intercellular Communication	There is an association between biomechanical stress and USPIO enhanced MR-defined inflammation within carotid atheroma, both known risk factors for plaque vulnerability.	17350023
Inflammation, Blood Clot	Altered Intercellular Communication	Inflammation within the thrombi was usually mild but moderate and severe inflammation was found in 13.4% and 1.3% of specimens, respectively.	17350667
Inflammation, Granuloma, Pulmonary arteritis, Neoplasms, Sarcoidosis, Blood Clot, PTEN gene, Malignant Neoplasms	Altered Intercellular Communication	In summary, pathology of PTE specimens in our study group encompassed remodeling of thrombi at various stages with variable degrees of inflammation and cellularity, granulomas associated with sarcoidosis, a rare case showing features of inflammatory myofibroblastic tumor, primary or metastatic malignancy, and isolated pulmonary arteritis.	17350667
Inflammation, Impaired cognition, Bipolar Disorder	Altered Intercellular Communication	Inflammation and interleukin-1 signaling network contribute to depressive symptoms but not cognitive decline in old age.	17350781
Behavioral and psychological symptoms of dementia, Inflammation	Altered Intercellular Communication	The association between inflammation and neuropsychiatric symptoms in old age is generally accepted but poorly understood.	17350781
Inflammation, Impaired cognition, Bipolar Disorder	Altered Intercellular Communication	The purpose of this study was to examine whether inflammation precedes depressive symptoms and cognitive decline in old age, and to identify specific inflammatory pathways herein.	17350781
Inflammation, Bipolar Disorder	Altered Intercellular Communication	A high innate IL-1ra to IL-1beta production capacity reflects a better ability to neutralize inflammation and may therefore protect against depressive symptoms.	17350781
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Although a direct correlation has yet to be proven between inflammation and prostate cancer, chronic or recurrent inflammation has been hypothesized to be the major predisposing factor for this disease.	17351029
Communicable Diseases, allergic inflammation, Tissue injury	Altered Intercellular Communication	In vivo recruitment of prMCs to different tissue compartments occurs in response to tissue injury, growth, and remodeling or allergic inflammation, allowing populations of circulating and potentially HIV-susceptible prMCs to spread persistent infection to diverse tissue compartments.	17351109
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Role of novel mediators of inflammation in left ventricular remodeling in patients with acute myocardial infarction: do they affect the outcome of patients?	17351157
Inflammation	Altered Intercellular Communication	The presence of inflammation in each of 7 ileocolonic segments was rated for every procedure.	17352384
Pharyngitis, Inflammation	Altered Intercellular Communication	Chronic nonspecific pharyngitis is a chronic inflammation of the pharynx.	17352845
Inflammation, Damage	Altered Intercellular Communication	Increased production of IL-1beta in FLS of susceptible individuals may lead to a higher risk of developing severe joint damage even in the absence of systemic inflammation.	17353049
Inflammation, Vascular Diseases	Altered Intercellular Communication	Several studies have found that an increased concentration of haemostatic or inflammation markers was associated with worse prognosis in vascular disease.	17353165
methyldopa, Inflammation	Altered Intercellular Communication	To investigate whether high-sensitivity C-reactive protein (hsCRP) and other biomarkers of inflammation predict age-related macular degeneration (AMD).	17353399
methyldopa, Inflammation	Altered Intercellular Communication	Elevated circulating levels of hsCRP, sICAM-1, and fibrinogen precede the development of visually significant AMD in women, providing further support for the hypothesis that inflammation may play a role in AMD.	17353399
Chronic inflammation	Altered Intercellular Communication	a) To evaluate the effect of Neptune Krill Oil (NKO) on C-reactive protein (CRP) on patients with chronic inflammation and b) to evaluate the effectiveness of NKO on arthritic symptoms.	17353582
Appendage, Inflammation	Altered Intercellular Communication	Epiploic appendagitis is a rare condition resulting from an acute inflammation of an appendix epiploica.	17354190
Inflammation	Altered Intercellular Communication	However, laboratory data showed mild inflammation without elevation of any cardiac enzymes.	17354584
Inflammation, Periodontitis	Altered Intercellular Communication	Association of height with inflammation and periodontitis: the Study of Health in Pomerania.	17355364
Inflammation, Periodontitis	Altered Intercellular Communication	Stratification for age and gender revealed that taller subjects had less periodontitis and decreased concentrations of markers of systemic inflammation than their shorter counterparts.	17355364
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	It is becoming increasingly evident that chronic inflammation may predispose cancer development.	17355416
Inflammation, Stomach Carcinoma, Infection caused by Helicobacter pylori	Altered Intercellular Communication	In the stomach, inflammation caused by Helicobacter pylori infection is linked to gastric cancer.	17355416
Communicable Diseases, Carcinogenesis, Stomach Carcinoma, Inflammation	Altered Intercellular Communication	To test whether a noninfectious long-standing inflammation impels gastric carcinogenesis as well, we assessed the risk of gastric cancer in a large, population-based cohort of cholecystectomized patients.	17355416
Celiac Disease, Inflammation	Altered Intercellular Communication	Celiac disease causes chronic inflammation of the intestinal mucosa and reduces surface absorption; after the withdrawal of gluten from the diet, there are clinical and histologic improvements.	17356917
Colagenosis, Inflammation	Altered Intercellular Communication	Typical features of all collagenosis are the connective tissue inflammation and the presence of autoantibodies in the patient's peripheral blood.	17357680
Inflammation, Retinitis Pigmentosa, Material Deformation	Altered Intercellular Communication	The main symptom of RP is the inflammation of the auricle, nose, nasal septum, laryngeal, tracheal and bronchial cartilages, which causes deformations of these organs.	17357680
Traumatic injury	Altered Intercellular Communication	An av-malformation may be stimulated by hormonal changes during puberty or pregnancy as well as by local trauma.	17357789
chronic inflammatory response, Anal Mucinous Adenocarcinoma	Altered Intercellular Communication	From our prospectively collected database, we identified 4 patients with chronic perianal inflammatory conditions who were subsequently found to have developed perianal mucinous adenocarcinoma on biopsy.	17357864
Neoplasms	Altered Intercellular Communication	A high index of clinical suspicion is required to make the diagnosis of perianal tumours while assessing patients presenting with perianal inflammatory conditions.	17357864
Inflammation, Blepharoptosis, Cellulitis	Altered Intercellular Communication	The inflammation under the upper eyelid may be sufficient to present as ptosis, however previously it has not been documented to cause a preseptal cellulitis.	17359543
Inflammation, Primary malignant neoplasm, Rheumatoid Arthritis	Altered Intercellular Communication	Persistent chronic inflammation contributes to the development of cancer in patients with rheumatoid arthritis from a defined population of northwestern Spain.	17360028
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Cancer mortality adjusted by age and sex was associated with chronic inflammation determined by C-reactive protein (CRP) (hazard ratio, HR, = 1.15; P < 0.001), and erythrocyte sedimentation rate (ESR) (HR = 1.05; P = 0.006).	17360028
Refractory anemias, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	However, the present data indicate that high-grade inflammation contributes to both the risk and the mortality of cancer in RA.	17360028
vascular inflammations, Albuminuria	Altered Intercellular Communication	Based on our data we hypothesize that weight-induced changes in vascular inflammation may cause changes in albuminuria.	17360767
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Excitatory neurotransmitter dysfunction has been discussed to be involved in the pathophysiology of Alzheimer's disease (AD).	17361039
Retinal Vein Occlusion, Inflammation	Altered Intercellular Communication	Inflammation measured by using highly sensitive C-reactive protein (hs-CRP) may be a separate risk factor in retinal vein occlusion (RVO).	17361257
Deficit, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	One of the most characteristic changes in Alzheimer's disease (AD) is a deficit in cortical cholinergic neurotransmission and associated receptor changes.	17361343
Inflammation	Altered Intercellular Communication	Inflammation was observed more frequently in patients, in both the media of left circumflex (p = 0.005) and adventitia of LAD artery (p = 0.024).	17361987
Refractory anemias, Inflammation, Atherosclerosis	Altered Intercellular Communication	There was less histologic evidence of atherosclerosis but greater evidence of inflammation and instability in RA patients compared to controls.	17361987
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Multiple endoscopic biopsies showed chronic inflammation without malignancy.	17362175
Inflammation, Diabetes Mellitus, atherosclerotic, Atherosclerosis	Altered Intercellular Communication	Diabetes mellitus accelerates atherosclerotic processes, and it is known that inflammation plays a key role in atherosclerosis.	17362204
Anxiety Disorders	Altered Intercellular Communication	The case might provide an initial piece of evidence that dopaminergic neurotransmission can be involved in the pathogenesis of generalized anxiety disorder.	17362439
Inflammation, Community-Acquired Infections	Altered Intercellular Communication	Accurate and timely diagnosis of community-acquired bacterial infections in patients with systemic inflammation remains challenging both for clinician and laboratory.	17362525
ARCN1 gene, Inflammation, Arterial Stiffness, Osteoporosis	Altered Intercellular Communication	We tested the hypothesis that patients with COPD would have increased arterial stiffness, which would be associated with osteoporosis and systemic inflammation.	17363772
ARCN1 gene, Inflammation, Osteoporosis	Altered Intercellular Communication	The increased aortic PWV in patients with osteoporosis and the association with systemic inflammation suggest that age-related bone and vascular changes occur prematurely in COPD.	17363772
Inflammation	Altered Intercellular Communication	Cytokines are protein mediators of inflammation and are produced as a result of the activation of various cellular reactions.	17364074
Intraocular inflammation	Altered Intercellular Communication	This etiology has to be considered in patients taking this drug who present with intraocular inflammation.	17364199
Inflammation, Traumatic injury, Neoplasms	Altered Intercellular Communication	MPR reconstructions were most useful in the assessment of skull base trauma, skull base tumours and in cases of chronic middle ear inflammation.	17364362
Inflammatory abnormality of the eye	Altered Intercellular Communication	The same patients were divided into three groups: (1) idiopathic ASNHL; (2) ASNHL associated with ocular inflammation, i.e.	17364500
Inflammation, Platelet destruction	Altered Intercellular Communication	ILD was detected in acute phase of platelet destruction, suggesting that platelet destruction may have triggered inflammation in the lung, leading to ILD.	17364997
Airway structure, Impaired	Altered Intercellular Communication	Ozone (O3) is known to induce lung function impairment and airways inflammation during episodes of photochemical smog.	17365589
Inflammation	Altered Intercellular Communication	Oestrogen receptors have been identified on B cells, T cells, and macrophages with oestrogens demonstrated to increase their activation and enhance RA synovial inflammation.	17365805
Inflammation	Altered Intercellular Communication	Histopathologic examination of the lesions revealed vaginal adenosis with chronic inflammation.	17366953
Stomatitis	Altered Intercellular Communication	Chronic inflammation of sinus mucosa is a multifactorial condition which sometimes results in irreversible pathological mucosal changes.	17367559
Inflammation, Pouchitis	Altered Intercellular Communication	Dysbiosis in pouchitis: evidence of unique microfloral patterns in pouch inflammation.	17368235
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Pouch inflammation after surgery for ulcerative colitis can significantly alter quality of life and thus ideally should be prevented.	17368235
Meckel Diverticulum, Chronic inflammation	Altered Intercellular Communication	The lesion was resected using an endoscopic stapler, and the histologic diagnosis was Meckel's diverticulum with chronic inflammation and calcification of the diverticular wall.	17368293
Granuloma, Inflammation, Periprosthetic Fractures	Altered Intercellular Communication	Histopathologic examination of the periprosthetic environment in two patients showed no signs of foreign body granulomas or chronic inflammation, despite distant effective silver concentrations up to 1626 ppb directly related to the prosthetic surface.	17368533
Inflammation, Atherosclerosis	Altered Intercellular Communication	H. pylori infection might be one of the risk factors of atherosclerosis thorough inflammation (fibrinogen) and modulation of glucose and lipid profiles, which may be prevented by low antibiotics in developing countries.	17368586
Coronary Arteriosclerosis	Altered Intercellular Communication	It is suggested that the calcium-regulating hormonal system is involved in the pathogenesis of the ischaemic heart disease; however the sharp increase of PTH and PTHrP at the severe stages of pathology may play a compensatory role in maintaining the heart function.	17368822
Hepatitis, Liver Cirrhosis	Altered Intercellular Communication	Prolonged liver inflammation can cause scarring, leading to cirrhosis.	17369071
Pancreatitis, Pathology, Malignant Neoplasms	Altered Intercellular Communication	The link between the two pathologies is supported in that pancreatic inflammation may play a role in the early development of pancreatic malignancy.	17371147
Inflammation	Altered Intercellular Communication	Comprehensive malnutrition inflammation score as a marker of nutritional status in Chinese peritoneal dialysis patients.	17371334
Inflammation, Thrombosis, Cardiac dysfunction	Altered Intercellular Communication	To investigate the natural history of platelet activation in PE and associated markers of inflammation, thrombosis and cardiac dysfunction.	17371486
Inflammation, Coughing, Lung Diseases, Interstitial, Lung Diseases, Obstructive, Lung diseases	Altered Intercellular Communication	We compared exhaled breath condensate (EBC) and induced sputum (IS) for assessing inflammation in pulmonary diseases in patients with obstructive lung disease (n = 20), persistent cough >6 months (n = 20), interstitial lung disease (n = 25) and controls (n = 10).	17372840
Inflammation	Altered Intercellular Communication	Chronic inflammation changes in the wall of the appendix bring about structural changes in the abdominal cavity.	17373110
Parkinson Disease, Neurodegenerative Disorders	Altered Intercellular Communication	Alpha-synuclein is involved in dopaminergic neurotransmission and has been implicated in a number of neurodegenerative disorders, such as Parkinson's disease.	17374033
Inflammation, Necrosis	Altered Intercellular Communication	Skin biopsy demonstrated dermal inflammation with foci of necrosis and multinucleated giant cells containing fungal spores.	17374319
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	Chronic inflammation converges in type 2 diabetes and atherosclerosis.	17374708
Inflammation, Neoplasms	Altered Intercellular Communication	It is generally agreed that elderly subjects undergo progressive deterioration of their immune responsiveness, which leads to an increased susceptibility to autoimmune processes, neoplasm and inflammation.	17374957
Inflammation	Altered Intercellular Communication	Thus there is a general consensus that regulation of inflammation results from a balance between pro-inflammatory and anti-inflammatory pathways.	17374957
Inflammation, Hemorrhage, Perforation (observation), Obstruction, Intestinal Volvulus	Altered Intercellular Communication	Complications include perforation, inflammation, bleeding, obstruction, and volvulus.	17375785
Communicable Diseases	Altered Intercellular Communication	This suggests that the increase in hepatic metabolism after TBI may be due to the increased presence of anti-inflammatory mediators in contrast to the inhibition effect of the pro-inflammatory mediators in non-TBI inflammation and infection.	17375982
Stomach Carcinoma, Gastritis	Altered Intercellular Communication	Improvement of gastric inflammation did not correlate with the discovery of gastric cancer after eradication; however, age at the time of eradication seemed to be important.	17376053
Inflammation, Appendicitis, CTCAE, Neoplasms	Altered Intercellular Communication	Based on a diagnosis of appendicitis with omental inflammation or an omental tumor, laparotomy performed.	17376061
Inflammation	Altered Intercellular Communication	This finding suggested that black males may respond to inflammation with a more aggressive rise in SF compared to white males.	17376255
Inflammation, Disseminated Intravascular Coagulation, Thrombophilia, SLC25A10 gene	Altered Intercellular Communication	Systemic inflammation can induce blood hypercoagulability, even disseminated intravascular coagulation (DIC), and "cross talk" exists between inflammatory and coagulation system.	17376263
Inflammation, Dysplasia	Altered Intercellular Communication	Fascin expression increased gradually with the progression from sinonasal epithelium with chronic inflammation, IP with mild dysplasia, IP with moderate dysplasia, IP with severe dysplasia, to cancerated IP, and significant difference of fascin expression was observed between any two groups of the five.	17376306
Irritation - emotion, Manufactured sign, Conjunctivitis	Altered Intercellular Communication	All patients showed dramatic resolution of ocular irritation, conjunctival inflammation, and all inflammatory, but not scarred, corneal signs; three patients showed improved vision.	17376393
Rosacea, Infestation by Demodex, Conjunctivitis	Altered Intercellular Communication	A variety of corneal pathologic features together with conjunctival inflammation, commonly noted in rosacea, can be found in patients with Demodex infestation of the eyelids.	17376393
Inflammation, Necrosis	Altered Intercellular Communication	A lymph node biopsy was then performed and showed a diffuse neutrophilic inflammation with abundant foamy macrophages, fat necrosis and lipogranuloma formation.	17377649
Gingivitis, Attachment (action), Diabetes Mellitus	Altered Intercellular Communication	Subjects with diabetes had increased gingival inflammation and attachment loss compared with controls.	17378885
Vasculitis, Hypertension, CTCAE, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Pioglitazone produces rapid and persistent reduction of vascular inflammation in patients with hypertension and type 2 diabetes mellitus who are receiving angiotensin II receptor blockers.	17379017
vascular inflammations, Hypertension, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	These results suggest that augmentation with pioglitazone further reduces vascular inflammation in patients with hypertension and diabetes who are receiving angiotensin II receptor blockers.	17379017
Inflammation, Influenza-like symptoms	Altered Intercellular Communication	The only AEs reported were mild and consistent with those expected after pegIFN alfa-2b administration, such as inflammation at the injection site and mild, brief, flu-like symptoms.	17379053
Inflammation, Asthma	Altered Intercellular Communication	Eosinophilic inflammation of the airways is a key characteristic of asthma.	17379492
allergic inflammation	Altered Intercellular Communication	Stimulation of eosinophils in airway with IL-5 and eotaxin may play a crucial role in allergic inflammation.	17379492
Asthma, Chronic Obstructive Airway Disease, Bronchitis	Altered Intercellular Communication	Bronchial inflammation and airway responses to deep inspiration in asthma and chronic obstructive pulmonary disease.	17379851
Airway structure	Altered Intercellular Communication	Airway inflammation has been suggested to alter airway mechanics during deep inspiration.	17379851
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	Inflammation in the airway smooth muscle bundles and submucosa of bronchial biopsies is positively associated with impaired airway mechanics during deep inspiration in asthma, but not in COPD.	17379851
Inflammation, Atherosclerosis	Altered Intercellular Communication	Our goal was to set up a pilot study to explore the possible relation between the expression of p66((ShcA)) and PTX3, two emerging regulators of stress response and inflammation processes, respectively, and the circulating levels of LDL-cholesterol (LDL), a factor implicated in the development of inflammation and oxidative-stress associated diseases such as atherosclerosis.	17380301
Inflammation, Atherosclerosis	Altered Intercellular Communication	In conclusion, our results suggest a potential link between the level of LDL and the expression of two genes involved in inflammation/oxidative stress pathways, i.e., p66((ShcA)) and PTX3, thus contributing to further understand the mechanism through which LDL may mediate the pathogenesis of inflammation and oxidative-stress associated diseases such as atherosclerosis.	17380301
Neoplasms, Malignant Neoplasms	Altered Intercellular Communication	The different tumours of the parotid gland can be divided in benign or malignant tumours, regional inflammations and enlarged lymph nodes.	17380314
Necrotizing granulomatous inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	The initial section may show extravascular granulomatous inflammation without evidence of vasculitis.	17381804
Inflammation, Arthritis, Collagen-Induced	Altered Intercellular Communication	Furthermore, injection of anti-CD44vRA mAbs reduced joint inflammation in DBA/1 mice with collagen-induced arthritis.	17383158
Inflammation	Altered Intercellular Communication	Quantifying alterations in protein synthesis and clearance rates is vital to understanding disease pathogenesis (e.g., aging, inflammation).	17383190
Inflammation, Observation Method - Coagulation, Depressed mood, Coronary heart disease	Altered Intercellular Communication	Heart rate variability and markers of inflammation and coagulation in depressed patients with coronary heart disease.	17383498
Inflammatory abnormality of the eye	Altered Intercellular Communication	The database includes details about ocular inflammation, including specific diagnosis, anatomic location, laterality, continuity, onset, complications, HLA-B27 status, and relative diagnostic certainty.	17383731
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	In addition, this study demonstrates the relationship between resistin and TNF-alpha in subjects with CKD and suggests that resistin may play a role in the sub-clinical inflammation associated with CKD, suggesting that adiponectin clearance may be decreased as shown by the inverse correlation of urinary adiponectin with GFR.	17383891
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Recent studies have reported that resistin is correlated with markers of inflammation and oxidative stress and is predictive of coronary atherosclerosis in humans.	17384443
Inflammation, Traumatic injury	Altered Intercellular Communication	Furthermore, inflammation and trauma are also considered to be predisposing factors.	17384479
Inflammation, Traumatic injury	Altered Intercellular Communication	In addition, neither patient had a history of occupation with exposure to excessive heat, inflammation or trauma.	17384479
Melanocytic nevus, Cholecystitis	Altered Intercellular Communication	Gallbladder inflammation is associated with increase in mucin expression and pigmented stone formation.	17385041
Cholecystitis, Biliary calculi	Altered Intercellular Communication	There is little information about a possible relationship between gallbladder inflammation and mucin expression or gallbladder stones' characteristics.	17385041
Cholecystitis	Altered Intercellular Communication	Pigmented brown stones were associated with a higher level of gallbladder inflammation.	17385041
Brown pigment gallstones	Altered Intercellular Communication	Inflammation of the gallbladder is accompanied by a higher level of MUC5AC expression and is associated with pigmented brown stones.	17385041
Inflammation, Orbital Myositis	Altered Intercellular Communication	Assessment of inflammation in idiopathic orbital myositis with fat-suppressed T2-weighted magnetic resonance imaging.	17386294
Inflammation, Orbital Myositis	Altered Intercellular Communication	To evaluate the inflammation in idiopathic orbital myositis by fat-suppressed T2-weighted magnetic resonance imaging (MRI).	17386294
Inflammation, Orbital Myositis	Altered Intercellular Communication	The inflammation in nine patients with orbital myositis was evaluated with fat-suppressed T2-weighted MRI within three weeks of onset.	17386294
Inflammation, Eye Movements	Altered Intercellular Communication	Of the five patients with acute improvement, none had inflammation of the extraocular muscles, whereas the four patients with chronic ocular motility restriction had inflammation of the extraocular muscles.	17386294
Inflammation, Orbital Myositis	Altered Intercellular Communication	These results suggest that acute or chronic pattern in orbital myositis is correlated with the localized inflammation.	17386294
Inflammation	Altered Intercellular Communication	The inflammation in the extraocular muscles may be one of the factors that lead to the chronic ocular motility restriction.	17386294
Inflammation	Altered Intercellular Communication	The hypothesis tested was that improved clearances of middle molecules with the FX80 membrane would lead to less oxidative stress and inflammation compared with the high-flux polysulfone (HF80) membrane.	17386321
Atherogenesis, Inflammation, Vascular System Injuries	Altered Intercellular Communication	Chronic low-grade inflammation may contribute to vascular injury and atherogenesis, and has been described in association to high blood pressure (BP).	17386341
Inflammation, Atherosclerosis	Altered Intercellular Communication	Sex related cardiovascular risk stratification based on quantification of atherosclerosis and inflammation.	17386928
Inflammation, Atherosclerosis	Altered Intercellular Communication	We evaluated the sex related cardiovascular risk stratification based on quantification of subclinical atherosclerosis and inflammation.	17386928
atherosclerotic	Altered Intercellular Communication	Measuring atherosclerotic inflammation may improve sex-related risk prediction in a general population.	17386928
Inflammation, Shock, Cardiogenic	Altered Intercellular Communication	Systemic inflammation, including expression of inducible nitric oxide synthase (NOS) and generation of excess nitric oxide, is believed to contribute to the pathogenesis and inappropriate vasodilatation of persistent cardiogenic shock.	17387132
Communicable Diseases, Psychiatric, Schizophrenia	Altered Intercellular Communication	Therefore, we suggest that TG infection, particularly in individuals with schizophrenia, is an important environmental factor in the interaction between psychiatric vulnerability, genetic background, immunomodulation, and the neurotransmitter systems.	17387159
Hepatitis A, Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	We prospectively examined unenhanced MR imaging findings in relation to pathologic fibrosis, inflammation and steatosis in patients with compensated chronic hepatitis C viral infection (HCV).	17387539
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	A combination of MRI and laboratory findings was most predictive of fibrosis and inflammation.	17387539
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	There are few studies of inflammation and hemostasis biomarkers and cardiovascular disease risk (CVD) in older adults.	17388967
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	But the biopsy specimens of the GUs showed chronic inflammation without malignant change or H. pylori infection.	17389157
Inflammation, "Alzheimers Disease", Data types - Address, Ischemia	Altered Intercellular Communication	Systemic inflammation is associated with ischemia and Alzheimer disease (AD).	17389308
Refractory anemias, Inflammation	Altered Intercellular Communication	The renin-angiotensin (RA) system including angiotensinogen (AGT), angiotensin I and angiotensin II influences the regulation of cell proliferation, angiogenesis and inflammation.	17389608
Inflammation, Atheroma	Altered Intercellular Communication	Patients with DE also had significantly thicker and more severe atheroma and a tendency toward more prominent inflammation and vascularity in pathologic findings.	17390201
Inflammation, atherosclerotic, Atherosclerosis	Altered Intercellular Communication	Delayed enhancement on CT demonstrated in over half of atherosclerotic AAA may be associated with chronic inflammation by atherosclerosis.	17390201
Inflammation, Hypoxemia	Altered Intercellular Communication	Hypoxemia, high pH and elevated inflammation markers predicted poor survival.	17391112
Inflammation	Altered Intercellular Communication	Histologic parameters evaluated were primarily those changes diagnostic of chronic inflammation or its sequelae.	17391315
Cereals, Inflammation, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Concordant with previous research, whole grain intake was inversely associated with obesity, insulin resistance, inflammation and elevated fasting glucose or newly diagnosed diabetes.	17391554
Communicable Diseases, Inflammation	Altered Intercellular Communication	E-selectin is expressed on activated endothelial cells and plays an important role in regulating the early steps of tethering and rolling of leukocytes into and within sites of infection and inflammation.	17392035
Carcinoma of lung	Altered Intercellular Communication	ABO phenotypes and inflammation-related predictors of lung cancer mortality: the Copenhagen Male Study - a 16-year follow-up.	17392322
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Inflammation and genetic susceptibility influence the risk of lung cancer.	17392322
Inflammation, Carcinoma of lung	Altered Intercellular Communication	The hypothesis that the association with lung cancer mortality risk of lifestyle and occupational factors previously linked to inflammation would depend upon ABO phenotype was tested in a long-term follow-up of 3,346 male subjects aged 53-74 yrs.	17392322
Carcinoma of lung	Altered Intercellular Communication	The predictive role of inflammation-related risk factors for lung cancer mortality was significantly stronger among males of phenotype O than A.	17392322
Cataract, Inflammatory abnormality of the eye, Unspecified visual loss	Altered Intercellular Communication	These cases were characterized by severe ocular inflammation occurring with a mean delay of 7.6 days after cataract surgery, severe visual loss (hand motions or less in three cases), and dense infiltration of the vitreous.	17392442
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Therefore, the aim of this study was to compare associations of markers of inflammation with type 2 diabetes risk between men and women.	17392546
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	These data suggest that binding of LIGHT with its receptors may play a role in the progression of inflammation within rheumatoid synovium, especially by mediating the interactions between infiltrating inflammatory cells and stromal cells.	17393389
Hidradenitis, Inflammation	Altered Intercellular Communication	Hidradenitis is a chronic and suppurative inflammation of the apocrine sudoriparous glands.	17393769
Inflammation, Spondylarthritis	Altered Intercellular Communication	Validation of the spondyloarthritis research consortium of Canada magnetic resonance imaging spinal inflammation index: is it necessary to score the entire spine?	17394179
Inflammation, Spondylarthritis, Spondylitis	Altered Intercellular Communication	The Spondyloarthritis Research Consortium of Canada (SPARCC) magnetic resonance imaging (MRI) spinal inflammation index has been developed to objectively measure inflammation in ankylosing spondylitis (AS) and to assess change in response to therapeutic intervention.	17394179
Inflammation	Altered Intercellular Communication	Scoring of the entire spine limits feasibility and a scoring method that records inflammation in only the more severely affected spinal segments may improve feasibility without sacrificing performance.	17394179
Inflammation	Altered Intercellular Communication	The SPARCC MRI spinal inflammation index performs better when analysis is limited to a maximum of 6 most severely affected levels compared with assessment of the entire spine.	17394179
Inflammation, Hyperplasia	Altered Intercellular Communication	Common histological features included obliterated ducts and chronic inflammation with, less frequently, neural hyperplasia (16.8%) and perineural invasion (3.2%).	17394497
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Glycated haemoglobin levels are related to chronic subclinical inflammation in renal transplant recipients without pre-existing or new onset diabetes.	17395658
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Subclinical glucose homeostasis alterations are related to chronic inflammation in renal transplant recipients without pre-existing or new onset diabetes and may contribute to their high cardiovascular mortality.	17395658
Inflammation, Cardiac dysfunction	Altered Intercellular Communication	We evaluated whether midregional proadrenomedullin reflects cardiac dysfunction, systemic inflammation or blood volume in haemodialysis patients.	17395664
Inflammation, Hypopyon, Corneal laceration	Altered Intercellular Communication	A 20-year-old man developed increasing inflammation with a hypopyon 3 weeks after primary repair of a corneal laceration.	17397754
Blindness, Inflammation, Pain Distress Question	Altered Intercellular Communication	The inflammation recurred, and the eye required enucleation because of blindness and intractable pain.	17397754
Fungal endophthalmitis, Traumatic injury	Altered Intercellular Communication	Fungal endophthalmitis should be considered in cases of delayed-onset inflammation after trauma and may be due to organisms resistant to amphotericin.	17397754
Inflammation, atherosclerotic	Altered Intercellular Communication	Histologically, the diseased valves appear to have areas of inflammation much like atherosclerotic plaques.	17398194
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	While the mechanism underlying the development of post-cardiothoracic surgery atrial fibrillation has not been fully elucidated, it has been suggested that inflammation may play a causative role.	17399635
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Corticosteroids have been traditionally used to reduce inflammation, and when administered perioperatively, they may decrease the incidence of atrial fibrillation.	17399635
Inflammation, cell injury	Altered Intercellular Communication	CFH and FHL-1 may act in concert in the eye and the reduced surface binding may result in inappropriate local complement control, which in turn can lead to inflammation, disturbance of local physiological homeostasis and progression to cell damage.	17399790
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Fatty degeneration	Altered Intercellular Communication	Fibrosis, steatosis and inflammation were staged according to the NAFLD activity score.	17399848
Inflammation	Altered Intercellular Communication	However, the reduction of false positives and the identification of old inflammation must be addressed.	17399962
Inflammation, Thrombosis, Atherosclerosis, Endothelial dysfunction, physiopathological	Altered Intercellular Communication	The neurogenic adventitial stress response may explain the local tissue remodeling seen in atherosclerosis, including adventitial adipose dysfunction, inflammation, adventitial angiogenesis, thrombosis, and endothelial dysfunction.	17400398
Inflammation, ovarian neoplasm	Altered Intercellular Communication	To estimate the association between prediagnostic levels of C-reactive protein (CRP), a marker of chronic systemic inflammation, and subsequent development of ovarian cancer.	17400857
ovarian neoplasm, Inflammation	Altered Intercellular Communication	If this association is causal, roughly 23% of ovarian cancer cases are attributed to chronic inflammation as indicated by elevated CRP concentrations.	17400857
ovarian neoplasm, Carcinogenesis, Inflammation	Altered Intercellular Communication	Higher circulating CRP concentrations in women who subsequently developed ovarian cancer support the hypothesized role of chronic inflammation in ovarian carcinogenesis.	17400857
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Depressive symptoms, omega-6:omega-3 fatty acids, and inflammation in older adults.	17401057
Intraocular inflammation, Macular Edema, Cystoid	Altered Intercellular Communication	Emulsified Densiron may have contributed to significant intraocular inflammation, epiretinal membrane formation and cystoid macular oedema.	17401320
Inflammation	Altered Intercellular Communication	Systemic inflammation may be associated with the pathogenesis of AMIMC.	17401747
Tumor necrosis, Gastrointestinal inflammation, Crohn Disease	Altered Intercellular Communication	Treatment with tumor necrosis factor-alpha monoclonal antibody (infliximab) reduces clinical activity and intestinal inflammation in Crohn's disease.	17402996
Tumor necrosis, Gastrointestinal inflammation	Altered Intercellular Communication	Rectal nitric oxide levels parallel down-regulation of inducible nitric oxide synthase, tumor necrosis factor-alpha, interleukin-1beta and interferon-gamma and may serve as a quantitative biomarker of intestinal inflammation.	17402996
Malignant neoplasm of esophagus, Inflammation	Altered Intercellular Communication	In conclusion, major upper gastrointestinal tract surgery in patients with oesophageal cancer elicits a catabolic response, characterized by increased inflammation, glucose production and protein breakdown.	17403267
Inflammation, Biliary calculi, Stenosis, Bile duct calculus, Postcholecystectomy Syndrome	Altered Intercellular Communication	The incidence rates of intraduodenal peri-ampullary diverticulum in patients with primary bile duct pigment stones, patients with bile duct stone and gallbladder stones, patients with bile duct stones originating from the gallbladder, patients with inflammation and stricture of the extremity of bile duct and papilla, patients with cancer of the extremity of bile duct and papilla, patients with post-cholecystectomy syndrome were detected by duodenoscope.	17403294
Stenosis, Inflammation, Bile duct calculus	Altered Intercellular Communication	The incidence rate of intraduodenal peri-ampullary diverticulum in patients with primary bile duct pigment stone was higher than that of patients with inflammation and stricture of the extremity of bile duct and papilla, patients with cancer of the extremity of bile duct and papilla and patients with bile duct stones originating from the gallbladder.	17403294
Inflammation	Altered Intercellular Communication	Residual inflammation was significantly increased in group A (31%) as compared to group B (11%) (p = 0.01).	17403357
Hyperglycemia, Inflammation	Altered Intercellular Communication	Synergistic relationship between hyperglycaemia and inflammation with respect to clinical outcomes in non-ST-elevation acute coronary syndromes: analyses from OPUS-TIMI 16 and TACTICS-TIMI 18.	17403721
Inflammation, Diabetes Mellitus, Hyperglycemia, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	To investigate the relationship between diabetes and inflammation and the potentially synergistic relationship between hyperglycaemia and inflammation on clinical outcomes in non ST-elevation ACS.	17403721
Inflammation, GDC AJCC Clinical Stage Terminology, Hyperglycemia, Diabetes Mellitus	Altered Intercellular Communication	Among ACS patients, diabetes was associated with both greater inflammation and higher glucose levels and patients with both hyperglycaemia and inflammation had worse outcomes.	17403721
Inflammation, Hyperglycemia, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Better control of both inflammation and hyperglycaemia should be assessed in future ACS trials as a means to reduce the cardiovascular risk among diabetics.	17403721
Inflammation, Stenosis	Altered Intercellular Communication	These strictures or stenoses develop secondarily to inflammation in the duct wall and may be single or multiple.	17403881
Inflammation, Carcinogenesis, Breast Cancer Cell	Altered Intercellular Communication	As the relationship between inflammation and carcinogenesis grows stronger, the role of cyclooxygenase-2 (COX-2) and epidermal growth factor (EGFR) has been highlighted in the pathogenesis and progression of human cancer.	17404027
Inflammation, CARCINOMA OF VULVA	Altered Intercellular Communication	Our article suggests that vulvar cancer in elderly patients may be associated with inflammation, and thus with increased COX-2 expression.	17404027
Inflammation	Altered Intercellular Communication	We infer that these findings are inconsistent with a nonselective secondary response of T cells to inflammation and instead suggest that clonally expanded alphabeta T cells are implicated in mediating a component of the valvular injury responsible for CAS.	17404318
Allergic asthma, Airway structure	Altered Intercellular Communication	Allergic asthma is characterized by airway inflammation initiated by adaptive immune responses to aeroallergens.	17404323
Inflammation, Asthma	Altered Intercellular Communication	Our study showed that neutrophilic inflammation and IFN-gamma expression were higher in induced sputum from severe asthma patients than from mild to moderate asthmatics.	17404323
Allergic sensitization, Inflammation, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	Animal experiments indicated that allergen sensitization with low-dose LPS (0.1 microg) induced type 2 asthma phenotypes, i.e., airway hyperresponsiveness, eosinophilic inflammation, and allergen-specific IgE up-regulation.	17404323
Inflammation, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	In contrast, allergen sensitization with high-dose LPS (10 microg) induced asthma phenotypes, i.e., airway hyperresponsiveness and noneosinophilic inflammation that were not developed in IFN-gamma-deficient mice, but unaffected in the absence of IL-4.	17404323
Inflammation, polychondritis, Collagen Diseases	Altered Intercellular Communication	Relapsing polychondritis is a rare rheumatologic disorder that is characterized by recurrent inflammation of selected connective tissue sites and destruction of cartilage throughout the body.	17404785
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation in Alzheimer's disease (AD) may be assessed using (R)-[(11)C]PK11195 and positron emission tomography.	17406654
Residue on Palate, Necrotizing	Altered Intercellular Communication	A 34-year-old patient presented with intraoral ulcerating, necrotizing inflammations of the palate and the gingiva.	17406921
Inflammation, Head of pancreas, Neoplasms	Altered Intercellular Communication	Male sex, large size of the pancreatic head mass (mean diameter 5.5 cm), and lack of atrophy of the pancreatic body and tail were the only features associated with chronic inflammation rather than neoplasm as an explanation for a pancreatic head mass.	17408158
Necrotizing granulomatous inflammation, Osteoporosis, Postmenopausal, Osteoporosis, Senile, Osteopenia	Altered Intercellular Communication	This study was conducted to determine whether olive fruits, rich in micronutrients, might improve bone loss in ovariectomized (OVX) rats (an experimental model of postmenopausal osteoporosis) and in OVX rats with granulomatosis inflammation (a model of senile osteoporosis).	17408530
Necrotizing granulomatous inflammation, Osteopenia	Altered Intercellular Communication	In OVX rats, granulomatosis inflammation, characterized by a rise in inflammatory parameters such as fibrinogen, alpha1-acid glycoprotein, spleen weight and granulocyte level, and an impairment of oxidative status (as shown by a decrease in plasma antioxidant capacity, a higher rate of isoprostane excretion) elicited a bone loss in the whole femur and in the metaphyseal areas considered on their own.	17408530
Inflammation, Osteoporosis, Senile, Osteopenia	Altered Intercellular Communication	The present data show that black olives are able to prevent bone loss in an experimental model of senile osteoporosis (oestrogen-deficient rats in which a low-grade inflammation was induced by talc injection).	17408530
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Markers of inflammation may predict both coronary artery disease (CAD) and adverse outcomes in patients with known CAD.	17408606
Inflammation, Enteral	Altered Intercellular Communication	Enteric glia regulate intestinal barrier function and inflammation via release of S-nitrosoglutathione.	17408650
Inflammation	Altered Intercellular Communication	We show that ablation of enteric glial cells in transgenic mice causes intestinal mucosal barrier dysfunction, resulting in inflammation.	17408650
vascular inflammations	Altered Intercellular Communication	This may be due to a higher level of vascular inflammation.	17408773
Inflammation, Anemia	Altered Intercellular Communication	This specific type of anemia has been termed anemia of chronic inflammation.	17408874
Inflammation, Anemia, Chronic disease	Altered Intercellular Communication	However, a substantial remainder of patients diagnosed with anemia of chronic disease present with no active inflammation.	17408874
Inflammation, Immobile, Anemia, Chronic disease	Altered Intercellular Communication	The non-specific umbrella term anemia of chronic disease thus becomes obsolete in favour of either the diagnosis of anemia of immobility or anemia of chronic inflammation according to the distinct mechanism involved.	17408874
Inflammation	Altered Intercellular Communication	Furthermore, the findings suggest that these structures contribute to temperature regulation of breath, protection against inflammation as well as breath frequency and depth-dependent mucus secretion.	17409747
Primary sclerosing cholangitis, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Primary sclerosing cholangitis is a chronic, progressive disease of inflammation and fibrosis of the bile ducts.	17410447
Inflammation	Altered Intercellular Communication	CT of the entire abdomen was performed just before the operation, which demonstrated inflammation in the omental fat.	17410738
Microsporidiosis, Gastrointestinal inflammation	Altered Intercellular Communication	However, microsporidian infections were not associated with intestinal inflammation as indicated by the lactoferrin test.	17412378
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Inflammation and the genes, molecules, and biological pathways that lead to inflammatory processes influence many important and disparate biological processes and disease states that are quite often not generally considered classical inflammatory or autoimmune disorders.	17412520
Parkinson Disease	Altered Intercellular Communication	We postulate a role for hypofunctional non-dopaminergic ascending neurotransmitter systems in spectral power changes in non-demented Parkinson's disease patients.	17412733
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Magnesium intake and plasma concentrations of markers of systemic inflammation and endothelial dysfunction in women.	17413107
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Relations between magnesium intake and systemic inflammation and endothelial dysfunction are not well established.	17413107
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Magnesium intake from diet is modestly and inversely associated with some but not all markers of systematic inflammation and endothelial dysfunction in apparently healthy women.	17413107
Inflammatory abnormality of the eye	Altered Intercellular Communication	The patient obtained psychological benefit by retaining the eye initially, but required subsequent enucleation for prolonged ocular inflammation.	17413639
Degenerative polyarthritis, Inflammation, Thrombosis	Altered Intercellular Communication	The extent to which the chronic inflammation of osteoarthritis requiring elective orthopedic surgery alters in-vivo coagulation and whether any specific alteration influences the development of postoperative thrombosis are unknown.	17413757
Inflammation	Altered Intercellular Communication	Chronic inflammation in the patients was thus associated with increased coagulation in vivo.	17413757
Communicable Diseases, Inflammation, Tissue injury, Traumatic injury	Altered Intercellular Communication	Neutrophil apoptosis is impaired in neonates, and this contributes to prolonged inflammation and tissue injury in infants after infection or trauma.	17413861
Perianal Squamous Intraepithelial Neoplasia, Inflammatory abnormality of the eye	Altered Intercellular Communication	Of 183 patients enrolled (mean age, 65.1 years; range, 25-91 years), 67% presented without lid margin disease, and 68% had no apparent ocular surface inflammation.	17413954
Inflammation	Altered Intercellular Communication	Symptoms were significantly more severe in patients with altered tear distribution or evident inflammation (P < 0.05).	17413954
Inflammation, Abnormally opaque structure (morphologic abnormality)	Altered Intercellular Communication	After systemic and topical antibiotic treatment, the opacity and inflammation of both eyes decreased.	17413971
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular surface inflammation may be induced by bacterial toxin reaction.	17413971
Low Vision, Hemorrhage, Granuloma of conjunctiva, Orbital Pseudotumor, Bayer Corneal Epitheliopathy Grade 1	Altered Intercellular Communication	Postoperatively, corneal epitheliopathy with reduced vision (6/60), orbital inflammation, inferior oblique underaction, and superomedial fornix symblepharon at the caruncular incision sight each occurred in one patient along with extensive subconjunctival hemorrhage and a suture-related conjunctival granuloma in others.	17414295
Depressive disorder	Altered Intercellular Communication	An activation of the immune system is discussed to trigger neurotransmitter changes and depressive illness.	17414324
Inflammation, Fibrosis Assessment, Telangiectasis, Traumatic injury	Altered Intercellular Communication	Histologic findings of trauma were as follows: parakeratosis (92%), dermal telangiectasias (61%), ulceration (51%), dermal inflammation (49%), melanin within stratum corneum (24%), and dermal fibrosis (25%).	17414433
Vasodilation, Inflammation	Altered Intercellular Communication	Vascular dilatation and lymphocytic chronic inflammation were present in the superficial dermis.	17414434
Inflammation	Altered Intercellular Communication	In addition, increased dermal mucin was present, with minimal fibroblast proliferation and inflammation.	17414447
Pneumonitis	Altered Intercellular Communication	Additional in vivo and in vitro experiments were performed to further analyze the contribution of S100A12 to pulmonary inflammation.	17414728
Pneumonitis	Altered Intercellular Communication	S100A12 expression may reflect neutrophil activation during lung inflammation and contribute to pulmonary inflammation and endothelial activation via binding to RAGE.	17414728
Inflammatory Bowel Diseases, Crohn Disease, Vaginal Fistula, Acute inflammation	Altered Intercellular Communication	Anovaginal fistulae (AVF) are frequently seen in patients with inflammatory bowel disease, especially in Crohn disease with active colonic inflammation.	17414761
Ischemia, Disorder of the optic nerve, Inflammation	Altered Intercellular Communication	The optic neuropathy has been attributed to ischemia, intrinsic inflammation of the optic nerve, or spread of inflammation to the nerve from adjacent intraconal orbital tissues.	17414867
Inflammation, Periostitis, Disorder of the optic nerve, Vasculitis, CTCAE, Autoimmune reaction	Altered Intercellular Communication	The periostitis, which is a manifestation of a systemic vasculitis or an autoimmune reaction to progenitors of cartilage, probably caused the optic neuropathy by compression or inflammation.	17414867
Sarcoma, Inflammation	Altered Intercellular Communication	We think the sarcoma probably developed gradually because of chronic inflammation and proliferation in the subdural collection.	17415183
allergic inflammation	Altered Intercellular Communication	Thymic stromal lymphopoietin (TSLP) is an IL-7-like cytokine that triggers dendritic cell-mediated Th2-type inflammatory responses and is considered as a master switch for allergic inflammation.	17416344
Myelitis	Altered Intercellular Communication	Most follow-up MR imaging examinations demonstrated less paraspinal inflammation and less epidural enhancement compared with baseline.	17416823
Cataract, Inflammation	Altered Intercellular Communication	This cataract developed because of repetitive inflammation of the anterior chamber and corticotherapy.	17417144
Hyperlipidemia, Hyperparathyroidism, Inflammation, Demographics Domain, Hyperhomocysteinemia, Diabetes Mellitus, Anemia, Obesity, Hypertension, CTCAE	Altered Intercellular Communication	Pts' data in association with the development of CAD that were recorded included age, sex, smoking habits, hypertension, obesity, the presence of diabetes mellitus (DM), hyperlipidemia, anemia, low albumin levels, secondary hyperparathyroidism (SHP), the presence of chronic inflammation, as evidenced by the presence of elevated levels of CRP and hyperhomocysteinemia.	17417765
Fibrosis Assessment, Nephritis	Altered Intercellular Communication	We, therefore, speculated the protective role of TGF-beta in renal inflammation rather than inducing fibrosis.	17417945
Nephritis	Altered Intercellular Communication	Thus, high-producing genotype of TGF-beta may be beneficial and may play a potential role in the resolution of renal inflammation.	17417945
vascular inflammations, Metabolic Syndrome X	Altered Intercellular Communication	Vascular inflammation evaluated by [18F]-fluorodeoxyglucose positron emission tomography is associated with the metabolic syndrome.	17418291
Arteritis	Altered Intercellular Communication	We investigated factors for carotid artery inflammation by [(18)F]-fluorodeoxyglucose (FDG) positron emission tomography (PET).	17418291
vascular inflammations, atherosclerotic	Altered Intercellular Communication	The FDG-PET is capable of identifying and quantifying vascular inflammation within atherosclerotic plaques.	17418291
Carotid Atherosclerosis, vascular inflammations	Altered Intercellular Communication	Vascular inflammation in carotid atherosclerosis was quantified by measuring the standardized uptake value (SUV) of FDG into the artery.	17418291
Inflammation, Metabolic Syndrome X, Carotid Atherosclerosis	Altered Intercellular Communication	Our present study may suggest that the metabolic syndrome is associated with inflammation in carotid atherosclerosis.	17418291
Inflammation	Altered Intercellular Communication	(Detection of Plaque Inflammation by Positron Emission Tomography (PET); http://www.clinicaltrials.gov/ct/show/NCT00114504; NCT00114504).	17418291
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is important in both the pathogenesis and outcome of atherosclerosis.	17418484
Inflammation	Altered Intercellular Communication	Current imaging techniques provide anatomic data but no indication of plaque inflammation.	17418484
Inflammation, atherosclerotic	Altered Intercellular Communication	Carotid atherosclerotic plaques contain a variable degree of inflammation which can be assessed in vivo by means of FDG and PET.	17418484
Inflammation, Arteriovenous fistula stenosis, Hyperplasia	Altered Intercellular Communication	In the stenotic arteriovenous fistula of hemodialysis patients, expression of the peptides IGF-I, IGFBP-1, -2, -3, -4 and IGF-R was significantly increased and showed a positive correlation with neointimal inflammation and hypercellularity (all p<0.05).	17418605
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	An apparent segmentary character of lesion (inflammation in the distal colon and an inflammatory focus in the cecum) is an additional criterion of unfavorable prognosis of transformation into disseminated UC forms.	17419355
Airway structure, ARCN1 gene	Altered Intercellular Communication	Single cigarette smoking causes acute reversible airway inflammation in everyone, and only 15 % of chronic smokers may develop chronic irreversible airway inflammation, resulting in the development of COPD.	17419375
Airway structure, Destruction (action)	Altered Intercellular Communication	Cigarette smoke may upregulate the pathways linked to lung destruction and airway inflammation, such as protease and oxidative stress, and may downregulate the pathways related to the defensive mechanism, such as antiprotease and antioxidant.	17419375
Inflammation, Cardiorespiratory failure, Scleritis	Altered Intercellular Communication	While the test results were pending, the patients' general condition worsened ; in particular, signs of active inflammation, cardiorespiratory failure and scleritis developed suddenly.	17419446
Inflammation	Altered Intercellular Communication	The inflammation of aging hypothesis purports that aging is the accumulation of damage, which results, in part, from chronic activation of inflammation process.	17419681
Inflammation, Fracture	Altered Intercellular Communication	Baseline markers of inflammation were higher among subjects who subsequently experienced an incident fracture.	17419681
Inflammation, Fracture, Osteoporotic Fractures	Altered Intercellular Communication	We conclude that elevated inflammatory markers are prognostic for fractures, extending the inflammation hypothesis of aging to osteoporotic fractures.	17419681
Solar lentigo	Altered Intercellular Communication	Compared with sun-protected skin, many inflammation-related genes were upregulated in solar lentigo, and compared with sun-exposed control skin, upregulation of genes related to fatty-acid metabolism was apparent in solar lentigo.	17419692
Inflammation, Solar lentigo	Altered Intercellular Communication	The results of the present microarray analysis of solar lentigo, demonstrating upregulation of genes related to inflammation, fatty-acid metabolism and melanocytes and downregulation of cornified envelope-related genes, suggest that solar lentigo is induced by the mutagenic effect of repeated ultraviolet light exposures in the past, leading to the characteristic enhancement of melanin production, together with decreased proliferation and differentiation of lesional keratinocytes on the background of chronic inflammation.	17419692
Inflammation, Infection, Acute Coronary Syndrome, atherosclerotic, Acute infectious disease	Altered Intercellular Communication	Systemic infections cause exaggerated local inflammation in atherosclerotic coronary arteries: clues to the triggering effect of acute infections on acute coronary syndromes.	17420787
Infection, Arteritis	Altered Intercellular Communication	We conducted an autopsy study to investigate the pathologic effect of systemic infections on coronary artery inflammation.	17420787
Inflammation, Necrosis, Fibrosis Assessment, Calcinosis, Deposition, SLC12A3 gene	Altered Intercellular Communication	Therefore, in NCC was found several general pathologic processes (necrosis, interstitial deposits, fibrosis, gliosis, inflammation) amongst which are highlighted beta-fibrillose in 13 (76.5%) cases associated to inflammatory process in 16 (94.1%) cases caused by the parasite, not yet related to NCC, and calcification present in viable and destruction parasites.	17420834
Hormone abnormality, Heredity, Osteoporosis, Chronic disease	Altered Intercellular Communication	The most important risk factors for osteoporosis are age, heredity, lifestyle, chronic diseases, hormonal abnormalities and physical characteristics of bone.	17424780
Lymphangioma, Inflammation	Altered Intercellular Communication	Because the lymphangioma persisted in spite of two repeated aspirations and with continued presence of inflammation, we used a transcervical approach to excise the cervical lymphangioma.	17425162
Communicable Diseases, Inflammation, Coronary Arteriosclerosis, Metabolic Syndrome X	Altered Intercellular Communication	The effects of metabolic syndrome versus infectious burden on inflammation, severity of coronary atherosclerosis, and major adverse cardiovascular events.	17426096
Inflammation, Atherosclerosis	Altered Intercellular Communication	The clinical predictors of inflammation in atherosclerosis remain controversial.	17426096
Communicable Diseases, Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	The objective of this study was to compare the associations of metabolic factors vs. infectious burden (IB) with inflammation, the severity of coronary atherosclerosis, and major adverse cardiovascular events (MACEs).	17426096
Inflammation, No metabolic abnormalities, Coronary Arteriosclerosis, Coronary Artery Disease	Altered Intercellular Communication	Compared with IB, metabolic abnormalities have a more prominent association with the degree of inflammation, the severity of coronary atherosclerosis, and the risk of MACE in patients with coronary artery disease.	17426096
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	The TNF superfamily member LIGHT has a T-cell co-stimulatory role and has previously been associated with inflammation and autoimmunity.	17426140
Inflammation	Altered Intercellular Communication	Correlation between LII and inflammation severity was revealed.	17426687
Inflammation, Apolipoprotein E, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Polymorphisms in the apolipoprotein E (Apo E) gene have been associated with lipid levels, carotid intima media thickness (CCA-IMT), inflammation and cardiovascular disease (CVD).	17426996
Eosinophilic inflammation	Altered Intercellular Communication	Results of this study suggest influence of eosinophil inflammation in respiratory tract on clinical status of CF patients.	17427145
Acute and chronic inflammation	Altered Intercellular Communication	[Blood cholesterol spectre in patients with acute and chronic inflammation of infectious origin].	17427430
Inflammation, Inguinal pain	Altered Intercellular Communication	Of them 68 had clinical complaints such as vaginal discharge, itching/irritation, inflammation and inguinal pain, while 132 had not any clinical complaints.	17427552
Inflammation	Altered Intercellular Communication	However, the patient had no abdominal symptoms and there was no evidence of peritoneal inflammation.	17427646
Hormone abnormality, Communicable Diseases, Fever, CTCAE	Altered Intercellular Communication	Extensive fever workups failed to show an infectious or inflammatory source and/or hormonal abnormality.	17427648
Granulomatous inflammation	Altered Intercellular Communication	Histopathological study of specimens taken from the right parotid tail mass showed granulomatous inflammation with acid-fast positive bacilli; culture later confirmed M. fortuitum.	17427970
Communicable Diseases, HIV Infections	Altered Intercellular Communication	In logistic regression models that included case mix and available surrogates of malnutrition-inflammation complex syndrome, HCV infection was associated with younger age, male gender, black race, Hispanic ethnicity, Medicaid insurance, longer dialysis vintage (duration), unmarried status, HIV infection, and smoking history.	17429053
allergic inflammation	Altered Intercellular Communication	Although activated platelets release a variety of mediators, the role of platelets in cutaneous allergic inflammation remains unclear.	17429435
Inflammation	Altered Intercellular Communication	These findings support that 5-HT activates monocytes and inhibits apoptosis, allowing them to remain in the tissue and contribute to chronic inflammation.	17429435
Granulomatous inflammation	Altered Intercellular Communication	Histological examination revealed a granulomatous inflammation with detection of acid-fast rods, albeit without fibrinoid necrosis.	17429583
Inflammation, Dysplasia, Metaplasia, Villous atrophy	Altered Intercellular Communication	Inflammation, villous atrophy, colonic metaplasia, and dysplasia have been observed within the mucosa of ileal pelvic pouches after restorative proctocolectomy.	17429711
Respiratory Tract Diseases	Altered Intercellular Communication	Because synthetic MMP inhibitors, capable of equilibrating the unfavorable MMP/TIMP-ratio, may be of potential therapeutic value in chronic respiratory tract diseases, the MMP functions in inflammatory conditions need to be carefully established.	17429873
Inflammation	Altered Intercellular Communication	It is tempting to assume that it is a drug-related lesion; perhaps, an area of plaque-related inflammation.	17430495
Cerebrovascular Disorders, Inflammation	Altered Intercellular Communication	Retinal vessel diameters and the role of inflammation in cerebrovascular disease.	17431876
Cerebrovascular Disorders, Inflammation	Altered Intercellular Communication	Our findings support the hypothesis that larger retinal venular diameters reflect systemic inflammation and suggest that inflammation is involved in cerebrovascular disease.	17431876
Inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Digital lesions in SLE were frequently painful (60%) with a finger-pulp inflammation (70%).	17432100
Inflammation, Failure	Altered Intercellular Communication	Inflammation was observed in 33.7% of the patients 12 months after ESS, especially in those with mucosa disfunction, draining failure and reverse draining.	17432350
Inflammation	Altered Intercellular Communication	The KDL lesion after ESS results in abnormal draining of maxillary sinus, and excessively large maxillary sinus opening may aggravate mucosa inflammation of maxillary sinus.	17432350
Inflammation	Altered Intercellular Communication	The abnormal draining state and mode may be related with the incidence of mucosa inflammation after operation.	17432350
Inflammation	Altered Intercellular Communication	H. pylori colonization and gastric inflammation was investigated by urease activity ((13)C-urea breath test), histology and serum pepsinogen I, II and gastrin-17 measurements.	17433799
Inflammation, Depression, CTCAE, Coronary heart disease	Altered Intercellular Communication	Depression and inflammation in patients with coronary heart disease: findings from the Heart and Soul Study.	17434456
Inflammation, Depression, CTCAE, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Depression and inflammation independently predict adverse cardiovascular outcomes in patients with coronary heart disease (CHD).	17434456
Inflammation, Depression, CTCAE, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Depression has been associated with elevated levels of inflammation in otherwise healthy patients without known CHD.	17434456
Inflammation, Depression, CTCAE, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	However, studies investigating the link between depression and inflammation in patients with established CHD have produced inconclusive results.	17434456
Inflammation, Unipolar Depression, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	We sought to examine the association of major depression with inflammation in 984 outpatients with established CHD from the Heart and Soul Study.	17434456
Inflammation, Depression, CTCAE, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	We found no evidence that current depression is associated with greater inflammation in outpatients with CHD.	17434456
Inflammation, Depression, CTCAE, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Inflammation is unlikely to explain the adverse cardiovascular outcomes associated with depression in patients with established CHD.	17434456
Inflammation	Altered Intercellular Communication	Recent studies have uncovered important cross talk between inflammation, generation of reactive oxygen and nitrogen species, and lipid metabolism in the pathogenesis of cardiovascular aging.	17434980
Inflammation, Cardiovascular system, Atherosclerosis	Altered Intercellular Communication	These findings suggest that pharmacological inhibition of FAAH may represent a novel protective strategy against chronic inflammation, oxidative/nitrative stress, and apoptosis associated with cardiovascular aging and atherosclerosis.	17434980
Inflammation, Uveomeningoencephalitic Syndrome	Altered Intercellular Communication	To identify prognostic factors for final visual outcome, development of complications, and recurrent inflammation in patients with Vogt-Koyanagi-Harada (VKH) disease.	17435968
Inflammation, Complication Aspects	Altered Intercellular Communication	Clinical findings at presentation, duration and method of tapering of systemic corticosteroids, and development of extraocular manifestations are significantly associated with final visual acuity, development of ocular complications, and recurrent inflammation.	17435968
Inflammation, Familial Mediterranean Fever	Altered Intercellular Communication	Inflammation continued both during the attack and attack-free period in FMF.	17436016
Inflammation, Familial Mediterranean Fever	Altered Intercellular Communication	Inflammation with increased acute phase reactants continued during both attack and attack-free periods in FMF patients.	17436016
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Weight decreased	Altered Intercellular Communication	The aim of this study was to test the hypothesis that systemic inflammation in patients with chronic obstructive pulmonary disease (COPD) is accompanied by enhanced interleukin 18 (IL-18) expression in skeletal muscle, which may precede muscle weight loss.	17436040
Inflammation, Infection caused by Helicobacter pylori, Gastroesophageal reflux disease, Carditis, Cardia of stomach	Altered Intercellular Communication	The etiology of inflammation of the gastric cardia (carditis) is controversial, and gastroesophageal reflux disease (GERD) and H. pylori infection have been proposed as etiological factors.	17436103
Inflammation, Cardia of stomach	Altered Intercellular Communication	These results suggest that GERD probably does not play a major role in the pathogenesis of inflammation in the gastric cardia.	17436103
Inflammation, Complication Aspects, Prodromal Symptoms, Eye Manifestations	Altered Intercellular Communication	Data extracted included age, gender, prodromal symptoms, visual acuity, ocular manifestations, extraocular findings, human leukocyte antigen (HLA), ocular complications, treatment, and smoldering inflammation.	17437061
Inflammation, Uveomeningoencephalitic Syndrome, Choroidal Detachment, Optic Disk, Cataract	Altered Intercellular Communication	The significantly higher incidence of optic disk hyperemia, choroidal detachment, and cataract, and the more frequent smoldering inflammation in elderly VKH patients indicate that special attention should be paid to these parameters in elderly patients.	17437061
Inflammation, Retinitis Pigmentosa, polychondritis	Altered Intercellular Communication	Relapsing polychondritis (RP) is a rare disease of unknown etiology causing systematic inflammation and resulting in destruction of cartilaginous tissues.	17437170
Airway structure, Inflammatory abnormality of the eye	Altered Intercellular Communication	We describe here an 18-year-old Japanese woman who developed severe airway stenosis as the initial symptom with auricular, nasal, and ocular inflammation.	17437170
Airway structure	Altered Intercellular Communication	This case illustrates the potentially fatal sudden onset of airway inflammation that can occur with this disorder, and the effectiveness of methotrexate.	17437170
Inflammation, Eosinophilic granulomatosis with polyangiitis, Vasculitis, CTCAE, Asthma, Hypereosinophilia	Altered Intercellular Communication	Churg-Strauss syndrome (CSS) is a rare form of systemic vasculitis occurring in patients with asthma and hypereosinophilia; however, its mechanisms involved in the severe tissue inflammation with vasculitis are poorly understood.	17437420
Inflammation	Altered Intercellular Communication	Interferon and other immunostimulatory medications can lead to an exacerbation of this preexisting low-grade chronic inflammation that is quite similar to interferon-triggered sarcoidosis.	17438184
Inflammation, PLP1 gene	Altered Intercellular Communication	This case raises questions about the role of inflammation in PLP1-related disorders and, conversely, PLP1 mutations in MS.	17438221
Inflammation, Cataract, Traumatic injury, Corneal Diseases, Glaucoma, CTCAE	Altered Intercellular Communication	Exclusion criteria were history of corneal disease, ocular trauma, inflammation, or previous glaucoma or cataract surgery.	17438428
Inflammation, Iron deficiency anemia, Obesity	Altered Intercellular Communication	Inflammation and iron deficiency in the hypoferremia of obesity.	17438557
Iron deficiency anemia, Obesity	Altered Intercellular Communication	Obesity is associated with hypoferremia, but it is unclear if this condition is caused by insufficient iron stores or diminished iron availability related to inflammation-induced iron sequestration.	17438557
Iron deficiency anemia, Obesity	Altered Intercellular Communication	We hypothesized that both inflammation-induced sequestration of iron and true iron deficiency were involved in the hypoferremia of obesity.	17438557
Inflammation, Saint Lucia, Obesity	Altered Intercellular Communication	However, the presence of inflammation alone or in combination with obesity and/or previous (especially upper) abdominal surgery is the main factor that influences the adverse outcomes of LC.	17439031
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	Recombinant human erythropoietin suppresses symptom onset and progression of G93A-SOD1 mouse model of ALS by preventing motor neuron death and inflammation.	17439481
Cessation of life, Inflammation, Amyotrophic Lateral Sclerosis	Altered Intercellular Communication	Multifactorial pathogenic mechanisms, including inflammation, attenuated survival signals and enhanced death signals, are involved in amyotrophic lateral sclerosis (ALS).	17439481
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	To evaluate associations between components of the Mediterranean diet and circulating markers of inflammation in a large cohort of asymptomatic subjects at high risk for cardiovascular disease.	17440519
Inflammation, Pain Distress Question, Toxic effect, Autoimmune Diseases, Erythema	Altered Intercellular Communication	In patients (n = 20), the vaccine was then administered weekly and showed very low toxicity, causing minor and tolerable local inflammation (erythema, papule, or local pain); only 1 patient who received a larger dose presented hot flashes, and there were no systemic manifestations of toxicity or autoimmune diseases attributed to the vaccine.	17441505
Inflammation, Granulomatous	Altered Intercellular Communication	All cases with the diagnosis of cysts with fungi, thorns, or splinters and associated granulomatous and acute inflammation were reviewed.	17442079
Granulomatous inflammation	Altered Intercellular Communication	Histologically, there was granulomatous inflammation with a variable degree of neutrophilic infiltrate giving central abscess formation.	17442079
Inflammation	Altered Intercellular Communication	The role of leptin in the modulation of the immune response and inflammation has been regarded as important.	17443329
Inflammation, Demographics Domain, Cancer-related fatigue, Chronic Kidney Diseases, Diabetes Mellitus, Anemia, neocytolysis	Altered Intercellular Communication	Anaemia in diabetes mellitus (DM) and/or chronic renal failure (CRF) may be caused by a decreased production of erythropoietin (EPO), EPO resistance, and by the lysis of the young circulating red blood cells (neocytolysis) induced by subclinical inflammation and low EPO level.	17444284
Stomach Carcinoma, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Immune responses to H. pylori are involved in gastric mucosal inflammation, and might affect clinical outcome, including the development of gastric cancer.	17444864
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Impact of inflammation on epigenetic DNA methylation - a novel risk factor for cardiovascular disease?	17444888
Inflammation, atherosclerotic	Altered Intercellular Communication	DNA methylation is an important cellular mechanism modulating gene expression associated with ageing, inflammation and atherosclerotic processes.	17444888
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus	Altered Intercellular Communication	Analysis by the Cox regression model demonstrated that DNA hypermethylation (HpaII/MspI ratio	17444888
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The present study demonstrates that global DNA hypermethylation is associated with inflammation and increased mortality in CKD.	17444888
Inflammation, Crohn Disease	Altered Intercellular Communication	Osteopontin, a protein with cytokine-like properties, is associated with inflammation in Crohn's disease.	17444956
Communicable Diseases, Inflammation	Altered Intercellular Communication	Immune response genes (IRG) play an important role in inflammation and control of infection after allogeneic transplantation.	17445163
Inflammation, polyps, Neoplasms, Allergy - Charge Type Reason, Traumatic injury	Altered Intercellular Communication	Sinus mucoceles rarely develop as a consequence of inadequate sinus ventilation that arises due to inflammation, allergy, polyps, tumors, surgery, and trauma.	17445623
Inflammation, Pain, Postoperative	Altered Intercellular Communication	Bromfenac ophthalmic solution 0.09% (Xibrom) for postoperative ocular pain and inflammation.	17445902
Eye pain, Photophobia, Inflammatory abnormality of the eye, Adverse event	Altered Intercellular Communication	Secondary outcomes included time to resolution of ocular inflammation, time to resolution of ocular pain, proportion of subjects with photophobia, and ocular adverse events.	17445902
Eye pain, Inflammatory abnormality of the eye	Altered Intercellular Communication	Bromfenac ophthalmic solution 0.09% effectively and rapidly cleared ocular inflammation and reduced ocular pain after CE.	17445902
Inflammation, Hypertensive (finding), Aortic Stiffness	Altered Intercellular Communication	Low-grade inflammation and hypoadiponectinaemia have an additive detrimental effect on aortic stiffness in essential hypertensive patients.	17446227
Inflammation, Hypertension, CTCAE, Aortic Stiffness	Altered Intercellular Communication	In essential hypertension, pronounced low-grade inflammation in conjunction with hypoadiponectinaemia exerts an additive detrimental effect on aortic stiffness, accelerating the vascular ageing process.	17446227
Inflammation, Hematoma, cell wall thickening, Communicable Diseases, Pseudoaneurysm, Aneurysm, Dystrophic calcification	Altered Intercellular Communication	Secondary signs, which helped predict the high likelihood of the diagnosis but could also be seen in graft infection or inflammation without AEF, were as follows (in descending order of frequency): effacement of the periaortic or perigraft fat plane and the fat plane between the aorta and bowel (nine patients, 100%), perigraft soft tissue (nine patients, 100%), bowel wall thickening adjacent to the graft (eight patients, 89%), perigraft fluid (seven patients, 78%), perigraft hematoma (six patients, 67%), pseudoaneurysm or aneurysm bulge (six patients, 67%), ectopic gas (five patients, 56%), and dystrophic vascular graft calcification (one patient, 11%).	17446540
Inflammation, Hemorrhage, Congenital MeSH qualifier, Traumatic injury	Altered Intercellular Communication	They may be congenital, or secondary to trauma, surgery, haemorrhage, or inflammation.	17447354
Refractory anemias, Inflammation	Altered Intercellular Communication	These results highlight the effect of the inflammatory process on the release of both Trx and Trx80 from RA synoviocytes, and suggest that the cytokine-induced increase in Trx80 cell release may constitute a link between inflammation and the immune system in RA.	17447898
Gingivitis, Dental Plaque	Altered Intercellular Communication	The study confirms the efficacy of three different preventive programmes in reducing supragingival plaque and gingival inflammation.	17448044
Granulomatous inflammation	Altered Intercellular Communication	The grains were embedded in an eosinophilic substance and surrounded by granulomatous inflammation.	17448202
ARCN1 gene, Inflammation, exacerbation acute	Altered Intercellular Communication	Systemic inflammation and systemic oxidative stress in patients with acute exacerbations of COPD.	17449234
ARCN1 gene, Inflammation	Altered Intercellular Communication	However, the relationships between systemic inflammation and parameters of oxidative stress in the systemic circulation during acute exacerbations of COPD remain to be explored.	17449234
ARCN1 gene, Inflammation, exacerbation acute	Altered Intercellular Communication	To analyze relationships between erythrocytic glutathione peroxidase (GPx), a marker of systemic oxidative stress, and parameters reflecting systemic inflammation, such as circulating neutrophils, C-reactive protein (CRP), and interleukin (IL)-6, in patients with acute exacerbations of COPD.	17449234
ARCN1 gene, Inflammation, exacerbation acute	Altered Intercellular Communication	Our study suggests an association between systemic inflammation and systemic oxidative stress reflected by erythrocytic GPx in patients with acute exacerbations of COPD.	17449234
Presenile dementia, "Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	Development of dementia, including Alzheimer's disease (AD), is associated with lipid dysregulation and inflammation.	17449329
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Patients with end-stage renal disease are thought to be in a chronic state of inflammation.	17449492
Appendicitis, CTCAE	Altered Intercellular Communication	The new CT criterion based on the maximum depth of the intraluminal appendiceal fluid greater than 2.6 mm is particularly useful for differentiating appendicitis without periappendiceal inflammation from a normal appendix with a diameter greater than 6 mm.	17449776
Airway structure	Altered Intercellular Communication	Fine particle exposures resulted in increased levels of FE(NO) in elderly adults, suggestive of increased airway inflammation.	17450216
Inflammation, Atrophic	Altered Intercellular Communication	Myeloperoxidase genotype is critical for development of atrophy in relation to the severity of inflammation.	17451207
Cerebral Amyloid Angiopathy, Seizures, Neurobehavioral Manifestations, Headache, vascular inflammations	Altered Intercellular Communication	A subset of patients with cerebral amyloid angiopathy (CAA) present with cognitive symptoms, seizures, headaches, T2-hyperintense MRI lesions, and neuropathologic evidence of CAA-associated vascular inflammation.	17452586
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Cerebral amyloid angiopathy-related inflammation represents a clinically, pathologically, radiographically, and genetically distinct disease subtype with implications for clinical practice and ongoing immunotherapeutic approaches to Alzheimer disease.	17452586
Inflammation, Myeloid Leukemia, Chronic	Altered Intercellular Communication	Circulating indicators of AGEs (CML and MG derivatives), although elevated in older participants, correlate with indicators of inflammation and OS across all ages.	17452738
Eosinophilic inflammation	Altered Intercellular Communication	T-cell-derived interleukin 5 (IL-5) and autosecretion of IL-5 from activated eosinophils may be causative reasons for the extension and persistence of eosinophil inflammation.	17453479
Inflammation, Cardiac Death	Altered Intercellular Communication	Non-cardiac deaths < or =30 days occurred later (206 [91,394] versus 41 [15,156] h, P<0.01) and were more frequently associated with signs of inflammation (43 versus 12%, P = 0.01) than cardiac deaths < or =30 days.	17453536
Inflammation, Cardiac Death	Altered Intercellular Communication	Non-cardiac deaths are associated with signs of inflammation.	17453536
Cardiovascular Diseases	Altered Intercellular Communication	Metabolic and hormonal changes associated with reproductive history may contribute to the development of cardiovascular diseases.	17453752
Sepsis, Inflammation, Blood coagulation	Altered Intercellular Communication	EPCR appears to be physiologically significant in the control of blood coagulation and inflammation and in the host response to gram-negative sepsis.	17454790
Inflammation, Deep thrombophlebitis	Altered Intercellular Communication	inflammation, are reported to induce LA and it is uncertain whether the association between LA and DVT is causal.	17454841
Inflammation, Deep thrombophlebitis, Lupus Erythematosus, Systemic	Altered Intercellular Communication	In this study the associations between aPL, LA and inflammation were investigated in 170 consecutive patients without SLE, but with a tentative diagnosis of DVT.	17454841
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation and coronary angiography in asymptomatic type 2 diabetic subjects.	17454845
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The samples were analyzed for the presence inflammation and fibrosis, both graded 0-3, as well as for any neoplastic changes without knowledge of the medical history, operative findings or final histology.	17454862
Inflammation, Infected	Altered Intercellular Communication	The PI correlated directly and significantly with inflammation in infected patients (r=0.45, p<10(-3)) and in cagA-positive patients (r=0.41, p=0.005).	17454874
Chronicity, Inflammation	Altered Intercellular Communication	HLA-B27 might have predictive value as a marker of chronicity of inflammation.	17454929
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	For differentiation between IBD, healthy controls and non-IBD gastrointestinal inflammation, the combination of gASCA, pANCA and ALCA had the best accuracy.	17456509
Inflammation, Obesity, Abdominal, Cardiovascular Diseases	Altered Intercellular Communication	Abdominal obesity is associated with low GH secretion, elevated circulating markers of inflammation, and increased risk of cardiovascular disease.	17456569
Cancer-related fatigue, Gingivitis, Dental caries	Altered Intercellular Communication	The CRF children had low prevalence of dental caries, although none of the clinical diagnoses displayed the absence of gingival inflammation.	17456959
Fibrosis Assessment, Myocarditis, Hypertrophy, Congestive heart failure	Altered Intercellular Communication	Congestive heart failure (CHF) is associated with altered energy homeostasis and myocardial inflammation, hypertrophy, and fibrosis.	17456982
Inflammation, No metabolic abnormalities, Cardiac fibrosis, myocardial injury	Altered Intercellular Communication	Patients with ongoing myocardial injury and high cTnT had associated findings consistent with activation of the sympathetic system, synthesis of cardiac fibrosis, inflammation and metabolic abnormalities.	17456983
Inflammation, Neoplasms	Altered Intercellular Communication	Since these subcutaneous tumors were likely due to inflammation by insulin, a biopsy sample was taken from the subcutaneous tumor of his right arm with his consent.	17457015
Esthesia, Irritation, Inflammation	Altered Intercellular Communication	All 40 eyes responded well to treatment and had long-term (average, 7.8 months) improvement of irritation and dry sensation and improvement of inflammation and staining of conjunctiva and cornea.	17457190
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Slit-lamp examination revealed a central corneal depression; the overlying epithelium was intact, and the stroma was thinned but lacked inflammation.	17457199
Inflammation, Angioedemas, Hereditary, Atrophy of lacrimal gland	Altered Intercellular Communication	Recurrent mucosal and soft-tissue inflammation secondary to HAE may lead to lacrimal gland atrophy.	17457207
Inflammation, Hemorrhage	Altered Intercellular Communication	Bleeding index and inflammation of gums fall average by 2.55 and 1.95.	17458096
Inflammation, Non-alcoholic Fatty Liver Disease, metabolic disturbance	Altered Intercellular Communication	Nonalcoholic fatty liver disease (NAFLD) is associated with several metabolic disturbances involving inflammation.	17458697
Steatohepatitis, Inflammation, metabolic disturbance, Cardiovascular Diseases	Altered Intercellular Communication	Subjects with hepatic steatosis showed an increased concentration of uCRP independently of other metabolic disturbances; this suggests an increased risk of cardiovascular diseases and could be used as a marker of chronic inflammation.	17458697
Astigmatism, Acute inflammation	Altered Intercellular Communication	The visual acuity improves quicker in the groups 1 and 2 of the 25-gauge ppv compared with the 20-gauge ppv due to less postoperative inflammation and to the practical absence of postoperative astigmatism.	17458795
Intraocular inflammation, Traumatic cataract	Altered Intercellular Communication	A traumatic cataract and an intraocular inflammation were diagnosed and treated elsewhere with phacoemulsification and anti-inflammatory drugs.	17458801
Vitreous inflammatory cells	Altered Intercellular Communication	Fundus examination revealed massive vitreous inflammation with a voluminous whitish chorioretinal infiltrate temporally.	17458801
Gastrointestinal inflammation	Altered Intercellular Communication	Plasma citrulline concentration: a reliable marker of small bowel absorptive capacity independent of intestinal inflammation.	17459021
Inflammation	Altered Intercellular Communication	Fifty-five patients were selected according to diagnosis, small bowel length, and degree of bowel inflammation.	17459021
Celiac Disease, Crohn Disease, Inflammation, Mesenteric infarction	Altered Intercellular Communication	(a) Crohn's disease (CD) with massive small bowel resection leaving 220) (N = 7), (d) CD without resection or active inflammation (normal CRP and CDAI <150) (N = 9), (e) mesenteric infarction (MI) with resection leaving	17459021
Gastrointestinal inflammation	Altered Intercellular Communication	Plasma citrulline concentration is a simple and reliable surrogate for small bowel absorptive capacity and is not influenced by intestinal inflammation.	17459021
Intraocular inflammation	Altered Intercellular Communication	A single posterior subtenon injection of TA can be as effective and safe as a 4-week regimen of prednisolone acetate 1% eyedrops in controlling intraocular inflammation after PPV.	17459031
Inflammation, Skeletal muscle weakness, Cachexia	Altered Intercellular Communication	The systemic features are skeletal muscle weakness and cachexia, the latter being associated with systemic inflammation.	17459894
Inflammation	Altered Intercellular Communication	N-Formyl peptide receptor-like 1 (fPRL1) is a member of the chemoattractant subfamily of G protein-coupled receptors and plays a key role in inflammation via chemotaxis and the regulation of mediator release from leukocytes.	17460114
Inflammation, Pyoderma	Altered Intercellular Communication	To clarify the alteration of neutrophil fPRL1 during inflammation in vivo, the immunohistochemical staining of neutrophil fPRL1 in samples from patients with purulent dermatitis was performed.	17460114
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation has recently proven to be associated with the pathogenesis of atherosclerosis and inflammatory genes are good candidates for the risk of developing atherosclerosis.	17460171
Inflammation, physiopathological	Altered Intercellular Communication	Summarizing z scores for inflammation and hemostatic dysfunction were calculated.	17460250
Inflammation, Helicobacter pylori, Gastroesophageal reflux disease, Carditis, Damage	Altered Intercellular Communication	"Carditis" (inflammation of the gastric cardiac mucosa) may be associated with gastroesophageal reflux disease (GERD), whereas other studies argue that Helicobacter pylori could play a significant role in the chronic cardiac damage.	17460453
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Histologic examination disclosed g0 in 8.3% patients, g1 in 78.4%, g2 in 12.8%, and g3 in 1; analysis of the cardia showed oxyntic mucosa in 27.9% patients and chronic cardiac mucosa inflammation in 72.1%.	17460453
Communicable Diseases, Inflammation	Altered Intercellular Communication	FDG PET showed foci of abnormally enhanced uptake in the soft tissue which was suggestive of inflammation in seven cases (43.75%) which were proven pathologically to be secondary to infection.	17460537
Inflammation, Primary Neoplasm	Altered Intercellular Communication	All the 18F-dopa-positive primary lesions were confirmed as being the primary tumour at histology, whereas of the other 12 unsuspected 18F-dopa-positive lesions, 11 were found to be metastatic deposits and one due to unspecific inflammation (one false positive result).	17460538
Airway structure	Altered Intercellular Communication	The persistence of airway inflammation depends on a decrease in apoptosis of T lymphocytes and eosinophils and survival of these activated cells.	17460949
Inflammation	Altered Intercellular Communication	T lymphocytes expressing gamma delta receptors can be identified in human lungs and play an important role in immune defence against pathogens and in the regulation of chronic inflammation.	17460949
Inflammation	Altered Intercellular Communication	The results obtained evidence for a positive action of imunophan on inflammation, immune status and antioxidant defense.	17460962
Inflammation, Acute myocardial infarction, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Systemic inflammation and apoptosis-specific immune activation play a major role in acute coronary syndromes (ACS) including acute myocardial infarction (AMI).	17461983
Inflammation, Helicobacter pylori, Stomach Carcinoma	Altered Intercellular Communication	The intensity of the inflammation induced by Helicobacter pylori colonization is associated with the development of distal gastric cancer (GC).	17462092
Inflammation, Blood Clot, Necrosis	Altered Intercellular Communication	Histologic examination of the resected aortic wall after the reoperation revealed tissue necrosis, severe local inflammation, and organization of old thrombi at the site of the glue application.	17462368
Inflammation, MS gene	Altered Intercellular Communication	HLA-G is upregulated at sites of inflammation in multiple sclerosis (MS) and assumed to counterbalance immune responses.	17462509
ARCN1 gene, Inflammation, Degenerative polyarthritis, Rheumatoid Arthritis, Chronic Obstructive Airway Disease, Disease	Altered Intercellular Communication	Our objective was to describe the impact of selected diseases involving chronic inflammation (chronic obstructive pulmonary disease [COPD], osteoarthritis, and rheumatoid arthritis) on mortality.	17462546
Malnutrition	Altered Intercellular Communication	BCM had a weak relationship with 7-point SGA (P = .267), malnutrition inflammation score (r = -0.27 P = .063), and patient-generated SGA (r = -0.27 P = .060).	17462551
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	It is well known that mast cells (MC) are involved in fibrosis and many forms of chronic inflammation.	17464452
Intrahepatic Route of Drug Administration	Altered Intercellular Communication	Prior co-infection of HBV in HCV patients may be an adverse risk factor for intrahepatic inflammation.	17465484
Inflammation, Anemia, deficiency aspects	Altered Intercellular Communication	In conclusion, most active TB patients had anaemia, which was probably due to inflammation and not to Fe deficiency since TB treatment without Fe supplementation was sufficient to restore Hb concentration.	17466092
Communicable Diseases, Inflammation, Lung diseases, Alcohol abuse	Altered Intercellular Communication	It was increased in a small number of patients with pulmonary disease, notably, pulmonary emboli, systemic infection or inflammation, and alcohol abuse.	17466411
Inflammation, Metabolic Syndrome X, Osage language	Altered Intercellular Communication	The association of OSA with insulin resistance, inflammation and metabolic syndrome.	17466499
Inflammation, Metabolic Syndrome X, Osage language	Altered Intercellular Communication	Inflammation, insulin resistance and metabolic syndrome increase with OSA severity.	17466499
Inflammation, Reduced visual acuity, Dispersion	Altered Intercellular Communication	Two years after implantation, posterior synechias persisted at the 3 o'clock position, with iris dispersion on the crystalline lens and the posterior side of the pIOL, but with no signs of anterior chamber inflammation and no visual acuity loss.	17466869
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Autoimmunity and longevity: presence of antinuclear antibodies is not associated with the rate of inflammation or mortality in nonagenarians.	17467040
Inflammation, SLC25A20 gene	Altered Intercellular Communication	Patients with and without CAC progression were compared with respect to clinical characteristics and biochemical variables, including lipid profile, parameters of mineral metabolism, and markers of inflammation.	17468488
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Of particular importance, chronic inflammation recently emerged as an important novel risk factor related to multiple complications of CKD.	17468489
palladium, Inflammation	Altered Intercellular Communication	Since inflammation and mortality risk are intimately related to both sides of those health issues, in this review we aim to analyze the peculiarities of inflammation and mortality risk in the Latin-American PD population.	17468489
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Systemic inflammation and repair of abdominal aortic aneurysm.	17468900
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Inflammation is integral to the pathogenesis of abdominal aortic aneurysm (AAA).	17468900
Inflammation	Altered Intercellular Communication	Extensive inflammation or fecal soilage may require colonic diversion.	17468926
Inflammation	Altered Intercellular Communication	Apart from inflammation in the skeletal muscle, overexpression of amyloid precursor protein (APP) and intracellular accumulation of its proteolytic fragment beta-amyloid play a central role in the pathogenesis of sIBM.	17469125
Inflammation	Altered Intercellular Communication	The presence of inflammation was indicated by C-reactive protein >5 mg/L or alpha1-acid glycoprotein >1 g/L.	17469727
Inflammation, Pain Distress Question, Leukocytosis, Fever, CTCAE, Osteomyelitis	Altered Intercellular Communication	Xanthogranulomatous osteomyelitis often presents as a severe chronic inflammation associated with pain, fever, and leukocytosis.	17470270
Inflammation, Traumatic injury	Altered Intercellular Communication	No inflammation or trauma was noted in either patient group.	17470306
Inflammation, Ulcer	Altered Intercellular Communication	The ulcers were congested and there was no inflammation, no polyps or other alterations in the mucosal layer.	17470326
Inflammation, Hyperplasia	Altered Intercellular Communication	The disease is characterized by severe but temporary epithelial hyperplasia with limited inflammation in the descending colon of adult mice on a variety of genetic backgrounds.	17470543
Inflammation, Hyperplasia	Altered Intercellular Communication	SW mice developed hyperplasia with minimal inflammation in the descending colon.	17470543
Inflammation, Epithelial Cell Proliferation, Superficial ulcer, Ulcer	Altered Intercellular Communication	FVB mice developed epithelial cell hyperproliferation, severe inflammation with erosions and ulcers, and epithelial atypia by 6 dpi in the descending colon.	17470543
Inflammation, Asthma	Altered Intercellular Communication	In conclusion, mast cells, through histamine and tryptase, may locally modulate airway smooth muscle-induced inflammation in asthma.	17470620
Inflammation	Altered Intercellular Communication	These results suggest that FKN might preferentially mediate migration and recruitment of CD16+ monocytes, and might contribute to synovial tissue inflammation.	17471309
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	KIM-1 was primarily expressed at the luminal side of dedifferentiated proximal tubules, in areas with fibrosis (alpha-SMA) and inflammation (MO).	17471468
Inflammation, Fibrosis Assessment, Kidney Diseases	Altered Intercellular Communication	In conclusion, KIM-1 is upregulated in renal disease and is associated with renal fibrosis and inflammation.	17471468
Inflammation, Kidney Diseases	Altered Intercellular Communication	uKIM-1 is also associated with inflammation and renal function, and reflects tissue KIM-1, indicating that it can be used as a non-invasive biomarker in renal disease.	17471468
Inflammation, Panniculitis	Altered Intercellular Communication	The term panniculitis refers to a heterogeneous category of conditions characterized by inflammation of subcutaneous adipose tissue.	17471839
Inflammation, Blood Clot	Altered Intercellular Communication	Ultrasound (USG) disclosed a large, irregular thrombus adhering to the margins of the mitral valve with signs of inflammation.	17471840
Inflammation, Malnutrition	Altered Intercellular Communication	Adjustment for case-mix and surrogate markers of malnutrition and inflammation attenuated, but did not reverse, this relationship.	17472839
Inflammation, Ischemic stroke	Altered Intercellular Communication	Thrombin activatable fibrinolysis inhibitor and its relationship to fibrinolysis and inflammation during the acute and convalescent phase of ischemic stroke.	17473579
Gastrointestinal inflammation	Altered Intercellular Communication	The significant correlation between the two fecal markers may be the expression of the ongoing intestinal inflammation.	17473939
Gastrointestinal inflammation	Altered Intercellular Communication	Lactoferrin fecal levels may be a reliable indicator for intestinal inflammation influencing the systemic inflammatory status.	17473939
Communicable Diseases, Inflammation, leukemia, Endocrine System Diseases	Altered Intercellular Communication	We conclude that no matter the temperature is normal or not, there were always neuroendocrine disturbance, inflammation, and inapparent infection in leukemia patient; To the leukemia patients with low leukocyte counts, the relationship between inflammation and neuroendocrine is more complicated.	17474895
Necrotizing granulomatous inflammation, Caseous necrosis	Altered Intercellular Communication	Fifteen (55.6%) of 27 with pleural biopsy demonstrated chronic granulomatous inflammation with or without caseous necrosis.	17475595
T-Cell Receptor gamma-Chain, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	TCRgamma PCR is more likely to be negative with moderate to severe inflammation, particularly with papillary dermal fibrosis.	17475602
Inflammation, Complete atrioventricular block, Hepatitis B	Altered Intercellular Communication	These new findings suggested that chronic inflammation may contribute to B7-H1 up-regulation on mDCs in CHB patients, which potentially cause defective hepatitis B virus-specific T cell function and viral persistence.	17475895
Balanitis	Altered Intercellular Communication	Neonatal circumcision and penile inflammation in young boys.	17475991
Balanitis	Altered Intercellular Communication	Penile inflammation was more common in circumcised than noncircumcised boys, especially in the first 3 years of life (exact odds ratio, 8.01, 95% confidence interval, 31-329.15).	17475991
Balanitis	Altered Intercellular Communication	The study found that rather than protecting against penile inflammation, neonatal circumcision increases the risk of penile inflammation, particularly in boys younger than 3 years old.	17475991
Inflammation, Headache	Altered Intercellular Communication	Progressive headaches and chronic inflammation of the adjacent mucous membrane are the most common symptoms.	17476198
Refractory anemias, Inflammation, Disease remission	Altered Intercellular Communication	RA patients with active disease showed marked insulin resistance that was not influenced by anti-TNFalpha therapy despite a reduction in systemic inflammation during the treatment.	17476613
Inflammation, Dysplasia, Carcinoma	Altered Intercellular Communication	Thus, a diagnostic procedure that enables the surgeon to differentiate inflammation from dysplasia and carcinoma in situ intra-operatively is urgently needed.	17476630
Refractory anemias, Inflammation, Tumor necrosis, Rheumatoid Arthritis	Altered Intercellular Communication	To determine if major reduction of inflammation with longterm tumor necrosis factor (TNF) antagonist treatment has any influence on the adrenal and gonadal axes in patients with rheumatoid arthritis (RA).	17477470
Presenile dementia, "Alzheimers Disease	Altered Intercellular Communication	Differential neuroimmune markers to the onset of Alzheimer's disease neurodegeneration and dementia: autoantibodies to Abeta((25-35)) oligomers, S100b and neurotransmitters.	17477976
Non-Neoplastic Disorder, Retractile Mesenteritis, Acute and chronic inflammation, Intestines, Small	Altered Intercellular Communication	Sclerosing mesenteritis is a rare non-neoplastic disease that affects the small bowel mesentery with chronic fibrosing inflammation.	17478346
Colitis	Altered Intercellular Communication	Identification of predictors of a diagnostic change could potentially impact the management of patients with colonic inflammation.	17478347
Grade 2 Liver Dysfunction or Failure by Clinical Classification, CTCAE, Inflammation, Communicable Diseases, Systemic Inflammatory Response Syndrome, Septic Shock	Altered Intercellular Communication	Plasma selenium and laboratory indices of organ dysfunction/failure, tissue inflammation, and infection were measured daily during the ICU stay in 60 consecutive ICU patients, 15 in each of four a priori defined subgroups: ICU controls (no SIRS); uncomplicated SIRS; severe SIRS; and severe sepsis/septic shock.	17478454
Inflammation, Grade 2 Liver Dysfunction or Failure by Clinical Classification, CTCAE	Altered Intercellular Communication	The minimum plasma selenium was inversely correlated to admission Acute Physiology and Chronic Health Evaluation II and Simplified Acute Physiology System II scores, indicators of inflammation, and the maximal degree of organ dysfunction/failure during the ICU stay.	17478454
Airway structure	Altered Intercellular Communication	Measurement of the fraction of nitric oxide in exhaled breath (Fe(NO)) has been proposed as a noninvasive marker of airway inflammation.	17478616
Chronic infectious disease, Chlamydia, Inflammation	Altered Intercellular Communication	Although chronic infection and persistent inflammation may contribute to the pathogenesis of EOC, and chlamydia is a common genital tract pathogen, our study did not find an association between chlamydia and EOC.	17479672
Inflammation, Primary malignant neoplasm, Thyroid carcinoma, Hashimoto Disease, Haiti	Altered Intercellular Communication	The link between inflammation and cancer is well-established, but the link between Hashimoto thyroiditis (HT) and thyroid cancer remains controversial.	17481480
Inflammation, Primary malignant neoplasm, Thyroid carcinoma, Haiti	Altered Intercellular Communication	Patients with HT were three times more likely to have thyroid cancer, suggesting a strong link between chronic inflammation and cancer development.	17481480
Airway structure, Asthma	Altered Intercellular Communication	Effects of montelukast compared to double dose budesonide on airway inflammation and asthma control.	17481879
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Two cases of peri-aortic inflammation are reported after receiving an abdominal endoprosthesis as treatment for abdominal aneurysm.	17482488
Inflammation, Atherosclerosis	Altered Intercellular Communication	These findings support the idea that the induction or exacerbation of inflammation could be a mechanism by which smoking promotes atherosclerotic cardiovascular diseases.	17484031
Stenosis of ureter, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Surgery was carried out and the pathologic study showed a bilateral ureteral stenosis secondary to fibrosis and chronic unspecific inflammation.	17484492
Crohn Disease, Inflammation	Altered Intercellular Communication	Patients (N = 509) with moderately to severely active Crohn's disease and active inflammation characterized by elevated C-reactive protein concentrations were randomized (1:1) to receive natalizumab 300 mg or placebo intravenously at Weeks 0, 4, and 8.	17484865
Microalbuminuria, Inflammation	Altered Intercellular Communication	The differential effects of angiotensin II type 1 receptor blockers on microalbuminuria in relation to low-grade inflammation in metabolic hypertensive patients.	17485023
Inflammation, Keratitis	Altered Intercellular Communication	Fortified ophthalmic solutions are used in severe keratitis (large diameter, stroma infiltration, inflammation of the anterior chamber, old patient).	17486040
Inflammation	Altered Intercellular Communication	Physiologic changes like puberty, the menstrual cycle, and pregnancy cause hormonal variations that may cause inflammation of the gingiva.	17486192
Inflammation	Altered Intercellular Communication	Physiologic changes like puberty, the menstrual cycle, and pregnancy cause hormonal variations that may cause inflammation of the gingiva.	17486192
Inflammation	Altered Intercellular Communication	The prevalence of male genital tract inflammation (as defined by PMN elastase > 250 ng/mL) and its severity increased significantly.	17486269
Inflammation	Altered Intercellular Communication	The significant increases of PMN-elastase levels as marker of male genital tract inflammation in older men appear to be indicative of age-related changes in local immunoregulatory mechanisms.	17486269
Inflammation, Ischemia, Atrial Fibrillation by ECG Finding, Abnormal cardiac conduction, Atrial Fibrillation	Altered Intercellular Communication	Atrial fibrillation (AF) may result from an electric conduction disturbance, increased hemodynamic stress, ischemia, inflammation, or remodeling in atria.	17487426
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Elevated levels of IL-6, hs-CRP and MMP-9 provide a link between inflammation, matrix degradation and the development and progression of ACS.	17487763
Genitalia, 46, XY Disorders of Sex Development	Altered Intercellular Communication	We report a SF-1 mutation that caused ambiguous genitalia associated with strikingly different hormonal phenotypes in two affected 46,XY children from the same family.	17488792
Inflammation, Acute myocardial infarction, Atherosclerosis	Altered Intercellular Communication	Inflammation has a major role in atherosclerosis and the acute phase C-reactive protein (CRP) is elevated after acute myocardial infarction.	17489343
Acute myocardial infarction, Inflammation	Altered Intercellular Communication	Increased levels of circulating CRP after acute myocardial infarction are associated with attenuated HRV indices, suggesting a possible relationship between inflammation and cardiac autonomic balance.	17489343
Tumor necrosis, Fibrosis Assessment, Inflammation, Neoplasms	Altered Intercellular Communication	Pathologic assessments of the extent of: tumour necrosis, fibrosis, macrophage infiltration, and tumour induced inflammation were graded on an ordinal scale of 0 to 2 (none/minimal, moderate, extensive).	17490737
Inflammation, Gastric Cardia Carcinoma	Altered Intercellular Communication	Continuous cardia inflammation may contribute to the high incidence of gastric cardia cancer in this region.	17492381
Symptoms, Gastritis	Altered Intercellular Communication	However, despite the bacterium persistence, significant improvement of dyspeptic symptoms and reduction of serologic signs of gastric inflammation were observed after 2 months at the end of the 7-day treatment schedule.	17493004
Inflammation	Altered Intercellular Communication	Reported herein is a rare case of xanthogranulomatous inflammation of the gastric wall occurring in a 77-year-old man.	17493178
Xanthogranulomatous inflammation, Reactive Cutaneous Fibrous Lesion	Altered Intercellular Communication	On macroscopic examination of the resected material, spontaneous regression of the lesions was observed and microscopic examination showed characteristic features of xanthogranulomatous inflammation; large numbers of foamy histiocytes including multinucleated giant cells were admixed with chronic inflammatory cells and fibrous reaction.	17493178
Inflammation, Impaired cognition	Altered Intercellular Communication	To determine whether circulating markers of activated inflammation and hemostasis are associated with cognitive decline in older people.	17493189
Inflammation, Comorbidity	Altered Intercellular Communication	Systemic markers of inflammation and hemostasis are associated with a progressive decline in general and specific cognitive abilities in older people, independent of major vascular comorbidity.	17493189
Inflammation, Impaired cognition	Altered Intercellular Communication	Systemic markers of inflammation and cognitive decline in old age.	17493190
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	This association was especially pronounced in participants with a high serum level of inflammation, resulting in an average 3MS score 0.64 points lower per year (P=.03) for those with metabolic syndrome.	17493197
Inflammation, Impaired cognition, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome and inflammation may both contribute to cognitive decline in older people of diverse backgrounds.	17493197
Granulomatous inflammation, Pineal germinoma, Neurosarcoidosis	Altered Intercellular Communication	We report a case of a 24-year-old man with a right thalamic germinoma that initially mimicked a granulomatous inflammation, compatible with neurosarcoidosis based on clinical symptoms, imaging results and histology of an endoscopically navigated biopsy.	17494513
Granulomatous inflammation, Pineal germinoma	Altered Intercellular Communication	We conclude that granulomatous inflammation in a specimen obtained by biopsy of a midline lesion should always be considered for the differential diagnosis of germinoma.	17494513
Inflammation, Pseudoaneurysm, Traumatic injury, Neoplasms	Altered Intercellular Communication	Pseudoaneurysms can arise due to localized arterial wall disruption, owing to various factors such as inflammation, trauma, neoplasm, or surgical procedures.	17495057
Inflammation, Coronary heart disease	Altered Intercellular Communication	Role of novel biomarkers of inflammation in patients with stable coronary heart disease.	17495262
Hypertrophy	Altered Intercellular Communication	Lumbar ligamentum flavum hypertrophy is due to accumulation of inflammation-related scar tissue.	17495768
Hypertrophy	Altered Intercellular Communication	To prove our hypothesis that hypertrophy of the ligamentum flavum is caused by accumulation of inflammation-related scar tissue.	17495768
Inflammation	Altered Intercellular Communication	There is a need for an in-depth investigation of any relationship between inflammation and scar formation in the ligamentum flavum.	17495768
Inflammation, Hypertrophy	Altered Intercellular Communication	If inflammation is related to hypertrophy, we may control/delay the hypertrophy by inhibiting the inflammation.	17495768
Tumor necrosis	Altered Intercellular Communication	Gene array results showed in both thin/control and hypertrophied ligaments expression of inflammation-related genes such as COX-2, tumor necrosis factor-alpha, and interleukin-1, 6, 8, and 15.	17495768
Airway structure, Asthma	Altered Intercellular Communication	Current asthma guidelines recommend adjusting antiinflammatory treatment on the basis of the results of lung function tests and symptom assessment, neither of which are closely associated with airway inflammation.	17496226
Inflammation, Infection	Altered Intercellular Communication	CRP is a reliable marker of the acute phase reaction to infections and/or inflammation and is a powerful predictor of future coronary events.	17496863
Refractory anemias, Inflammation, Damage	Altered Intercellular Communication	There was no correlation between KIR expression and disease activity; therefore, the clinical use of KIR expression should be limited, while unnatural KIR expression may be involved in the pathogenesis of RA, but not a recruitment of chronic inflammation to induce joint damage.	17497034
Inflammation, Coronary Artery Disease, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP) which is among the most sensitive markers of systemic inflammation, and elevation of systemic and local levels of this inflammatory marker which has been associated with an increased risk for cardiovascular disease in the obstructive coronary artery disease (O-CAD) are well known, but little was known in CAE.	17497040
MRSA - Methicillin resistant Staphylococcus aureus infection, Inflammation, Septicemia	Altered Intercellular Communication	Seven days later, she developed methicillin-resistant Staphylococcus aureus septicemia and CT scan evidence of perivascular inflammation around the left common iliac artery.	17497070
HD Term Type, Inflammation	Altered Intercellular Communication	Elevated resistin related to markers of inflammation may represent a novel link between inflammation and adipocytokines in HD patients.	17498119
Renal Insufficiency, Inflammation, HD Term Type	Altered Intercellular Communication	Impaired renal function and inflammation are responsible for elevated resistin in HD patients.	17498119
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Each TJLB was blindly coded; the pathologist randomly assessed: (a) each core separately covering the other two, (b) two cores simultaneously covering the third and (c) the three cores together for diagnostic yield, inflammation and fibrosis.	17498250
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Three non-fragmented cores (each core >/=7mm in length) of TJLB can be considered a minimum requirement for histological assessment, giving better reproducibility in diagnosis as well as for inflammation and fibrosis.	17498250
Inflammation, Osteochondritis Dissecans, Cognition Disorders	Altered Intercellular Communication	We hypothesized that candidate gene polymorphisms in biologic pathways regulating inflammation, cell matrix adhesion/interaction, coagulation-thrombosis, lipid metabolism, and vascular reactivity are associated with postoperative cognitive deficit (POCD).	17498578
Inflammation, Thrombosis, Carcinogenesis, Lip and Oral Cavity Carcinoma	Altered Intercellular Communication	In light to recently found contribution of factors associated with angiogenesis, thrombosis and inflammation to carcinogenesis, we investigated the possible association of metalloproteinase-9 (MMP-9) with increased risk of oral cancer.	17498910
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Outcomes included normalization of laboratory evidence of inflammation, regression of fibrosis by computerized tomography and the ability to discontinue ureteral stents.	17499287
Atherosclerosis, Acute suppurative inflammation	Altered Intercellular Communication	On pathological examination, aortic atherosclerosis was present in all cases, acute suppurative inflammation was present in 31 patients (65%), and bacterial clumps were present in five patients (10%).	17499963
Cessation of life, Aneurysm, Inflammation	Altered Intercellular Communication	Although statistically insignificant, local purulent infection with positive culture of the aneurysm wall, gross pus during operation, or acute suppurative inflammation on pathology tended to be associated with high risk of prosthetic graft infection and aneurysm-related death.	17499963
Inflammation	Altered Intercellular Communication	On pathology, acute suppurative inflammation was present in the majority of cases but bacterial clumps were not commonly present.	17499963
Inflammation, Organ dysfunction syndrome	Altered Intercellular Communication	The pathogenesis of the post cardiopulmonary bypass (CPB) organ dysfunction syndrome is complex, with inflammation being an important component.	17499999
Inflammation, Renal function, Damage, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Factors associated with low BMD in SLE are high age and low weight but also markers of inflammation, impaired kidney function and disease damage, however glucocorticosteroids were not associated.	17500075
Inflammation, Idiopathic Inflammatory Myopathies, Edema	Altered Intercellular Communication	Acute inflammation in idiopathic inflammatory myopathies (IIM) causes oedema that can be visualized by magnetic resonance imaging (MRI).	17500079
physiopathological	Altered Intercellular Communication	Uncorrected, this can result in hormonal dysfunction, decreased fertility, and difficult and unclear situations during abdominal surgery in adulthood.	17502174
Inflammation, Heart valve regurgitation	Altered Intercellular Communication	Role of inflammation in nonrheumatic, regurgitant heart valve disease.	17502247
Inflammation	Altered Intercellular Communication	The signs of inflammation seen in nonrheumatic aortic stenosis are not prominent features in the nonrheumatic, regurgitant valves.	17502247
Inflammation, Rheumatoid Factor, Hypercatabolism	Altered Intercellular Communication	Cigarette smoking associates with increased BMR in healthy individuals; it is also related with worse disease outcomes in patients with rheumatoid arthritis(RA), in whom BMR is high due to hypercatabolism caused by systemic inflammation.	17502358
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) patients experiencing frequent exacerbations demonstrate increased stable-state airway inflammation.	17504798
Airway structure	Altered Intercellular Communication	Tiotropium has been shown to reduce exacerbation frequency, but its effect on airway inflammation is unknown.	17504798
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Tiotropium reduces exacerbation frequency in chronic obstructive pulmonary disease, but this effect does not appear to be due to a reduction in airway or systemic inflammation.	17504798
Pneumonitis	Altered Intercellular Communication	Their function may be to control pulmonary inflammation.	17505034
Airway structure	Altered Intercellular Communication	We investigated whether BMI and FFMI could be related to parameters expressing airflow obstruction and limitation, exercise capacity, airway inflammation, and quality of life, and whether they would reflect the GOLD staging of the disease.	17505043
Inflammation	Altered Intercellular Communication	Is adipocyte size associated with inflammation in adults?	17505154
Inflammation, Depression, CTCAE, Vascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP) is a non-specific marker of inflammation that has been associated with depression and vascular disease, particularly in men.	17506927
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	There is increasing evidence suggesting that inflammation is involved in the development of hypertension.	17508011
Inflammation, Pancreatitis, Malnutrition, Gall Bladder Diseases, Renal Insufficiency	Altered Intercellular Communication	In conclusion, the amount and amylase concentration of postsurgical drainage after distal pancreatectomy for chronic pancreatitis is dependent on markers of renal dysfunction, malnutrition, biliary disease, and possibly inflammation.	17508252
Inflammation	Altered Intercellular Communication	Cyclooxygenase-1 (COX-1) is a key enzyme involved in generation of prostanoids, important mediators and modulators of asthmatic inflammation.	17508966
Orbital Pseudotumor	Altered Intercellular Communication	Initially, non-specific orbital inflammation was suspected while investigations were ongoing.	17510871
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	A Toll-like receptor 7 single nucleotide polymorphism protects from advanced inflammation and fibrosis in male patients with chronic HCV-infection.	17512627
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We analyzed the effect of TLR7 SNPs on grade of inflammation and stage of fibrosis as determined by liver biopsy.	17512627
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Our data suggest that the c.1-120G TLR7 allele offers protection from the development of inflammation and fibrosis in male patients with chronic HCV-infection.	17512627
Inflammation, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	In both atherosclerosis and cardiovascular disease, oxidative stress and inflammation have been implicated as underlying pathophysiologic mechanisms.	17513169
Inflammation, pustule, Infection	Altered Intercellular Communication	Overall, there were 9 cases of local inflammation at the insertion site (0.6%), and 3 local infections (pustule) (0.2%, all femoral CPNBs).	17513661
Communicable Diseases, Inflammation, Depression, CTCAE	Altered Intercellular Communication	CBT holds promise for improving depression and immunity and reducing infection and inflammation after CABG.	17515020
Toxic effect	Altered Intercellular Communication	The literature also suggests that low-dose ketoconazole may be an appropriate second- or third-line hormonal agent in AIPC, causing a PSA decline, symptomatic relief, and minimal toxicity.	17515709
Communicable Diseases, Inflammation, hepcidin	Altered Intercellular Communication	Recently identified hepcidin, exclusively synthesized in the liver, is thought to be a key regulator for iron homeostasis and is induced by infection and inflammation.	17515961
Granulomatous inflammation, Granulomatosis with polyangiitis, Vasculitis, CTCAE	Altered Intercellular Communication	Wegener's granulomatosis (WG) starts with granulomatous inflammation of the respiratory tract before it converts into a potentially organ and life threatening systemic vasculitis associated with anti-neutrophil cytoplasmic antibodies (ANCA).	17516076
Inflammatory abnormality of the eye, Glaucoma, CTCAE, Siderosis	Altered Intercellular Communication	No ocular inflammations, siderosis or secondary glaucoma occurred in the described cases.	17516375
Kidney Failure, Chronic, Inflammation, Vascular Diseases, Uremia	Altered Intercellular Communication	In end-stage renal disease (ESRD) endothelium may represent a key target for the action of circulating elements, such as modified erythrocytes (RBC) and/or plasmatic factors, that may facilitate inflammation and the vasculopathy associated with uremia.	17516566
Communicable Diseases, Inflammation	Altered Intercellular Communication	Infection at titanium implants with or without a clinical diagnosis of inflammation.	17517058
Inflammation, Pancreatitis, "2,2-azobis(2-(2-imidazolin-2-yl) propane) dihydrochloride", Autoimmune Pancreatitis, Cholangitis	Altered Intercellular Communication	Immunoglobin G (IgG) 4-related sclerosing pancreatitis and cholangitis (autoimmune pancreato-cholangitis [AIPC]) are recently recognized disease entities characterized by high serum IgG4 concentrations and sclerosing inflammation with numerous IgG4-positive plasma cells, although the underlining immune mechanism remains only speculative.	17518371
Pancreatitis, Fibrosis Assessment, AURKAIP1 gene, Autoimmune Pancreatitis, Waldenstrom Macroglobulinemia	Altered Intercellular Communication	Autoimmune pancreatitis (AIP) is a unique form of chronic pancreatitis generally observed in aged people and characterized by the presence of autoantibodies,(1-3) elevated levels of immunoglobulins,(4) enlargement of the pancreas (diffuse or focal) on ultrasonography (US) or computed tomography (CT),(1-3,5) diffuse narrowing of the main pancreatic duct (MPD) with an irregular wall,(1,3,5-8) and pathologic features of dense lymphoplasmacytic inflammation and fibrosis, as well as a favorable response to steroid therapy.	17520215
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Residual inflammation at the corpus lesser curve was more frequently detected in the cancer group than in the controls (OR 4.6 95% C.I.	17520681
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver tests did not reflect the presence or degree of inflammation or fibrosis.	17520743
Inflammation, Arthritis, Traumatic injury	Altered Intercellular Communication	To further understand the role for NK cells in inflammation, we investigated the phenotype and function of synovial fluid (SF) NK cells from patients with chronic joint inflammation, as well as from patients with transient inflammation of the knee following trauma.	17521371
Helicobacter pylori, Acute and chronic inflammation	Altered Intercellular Communication	The chronic active inflammation caused by Helicobacter pylori is dominated by neutrophils, macrophages, lymphocytes and plasma cells.	17521392
Gastritis	Altered Intercellular Communication	There was a significant decrease in gastric inflammation in H. pylori-positive patients from both groups.	17521392
Refractory anemias, Inflammation	Altered Intercellular Communication	However, the role of the inhibitory FcgammaRIIb in the regulation of the synovial inflammation in RA is less known.	17521421
Refractory anemias, Inflammation	Altered Intercellular Communication	This study demonstrates for the first time that RA patients do not fail to up-regulate FcgammaRIIb upon synovial inflammation, but suggests that the balance between expression of the inhibitory FcgammaRIIb and activating FcgammaRs may be in favour of the latter throughout the disease course.	17521421
Inflammation	Altered Intercellular Communication	Recent evidence, however, suggests that a decrease in circulating high-density lipoprotein cholesterol (HDL-C) may occur during lymphomagenesis, reflecting underlying etiology such as inflammation.	17522388
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	The aims of this study were to determine, in peripheral blood mononuclear cells (PBMC), whether particulate antigen triggers (i) an amplified cell proliferative response compared to soluble antigen and (ii) a dysfunctional response in cells derived from patients with chronic inflammation and specifically in those with inflammatory bowel disease (IBD).	17522811
Inflammation	Altered Intercellular Communication	Frequently, it showed chronic inflammation with polyclonal plasmocytic infiltration.	17522889
Pancreatitis, Acute, Communicable Diseases, Inflammation	Altered Intercellular Communication	Synbiotic control of inflammation and infection in severe acute pancreatitis: a prospective, randomized, double blind study.	17523328
Gastritis, Peptic Ulcer, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Severe gastric inflammation or ulcer disease can alter gastric motility and influence sufficient glycemic control in patients with type 2 diabetes mellitus.	17523341
Inflammation, Gastric erosions, Gastritis, Ulcer	Altered Intercellular Communication	Highly active gastric inflammation was found in 34 patients (gastric ulcers in 10, gastric erosions in 21, and histologically acute, grade two or three gastritis in 3 patients).	17523341
Heartburn	Altered Intercellular Communication	Episodic heartburn was significantly associated with highly active gastric inflammation (odds ratio 2.96 (1.05-8.32), p = 0.036).	17523341
Gastritis, Inflammatory disorder	Altered Intercellular Communication	Elevated levels of C-reactive-protein and blood leukocyte counts proved to be of positive predictive value for highly active gastric inflammation in patients without other causes of acute inflammatory diseases (odds ratio 3.52 (p = 0.026) and 7.64 (p = 0.007) respectively).	17523341
Gastritis, Peptic Ulcer, Diabetes Mellitus	Altered Intercellular Communication	The results of this study indicate that severe acute gastric inflammation or ulcer disease can occur with high prevalence in patients with diabetes mellitus with little or no dyspeptic symptoms.	17523341
Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is an autoimmune disease characterized by a persistent inflammation of the synovium, leading to the erosion of articular cartilage and bone.	17523945
Arthritis	Altered Intercellular Communication	Synovial mast cells and their effector molecule, histamine, receive increased attention as mediators of joint inflammation.	17523945
Inflammation, Arthritis	Altered Intercellular Communication	Our experiments on animals show that histamine on its own neither induces inflammation in the joint cavity nor influences the course of HMGB1 and peptidoglycan-induced joint inflammation.	17523945
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histological grading of inflammation and staging of fibrosis in the livers were also compared and analysed in patients with different levels of serum ALT.	17524261
Hepatitis	Altered Intercellular Communication	Between the two groups of patients there were no significant differences in the histological grades of liver inflammation or in the hepatocytic expressions of HBsAg and HBcAg.	17524261
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Spearman's analysis indicated that the inflammation grade (G) was correlated with the hepatic fibrosis index PCIII, and the correlation coefficient was 0.391 (P = 0.003).	17524262
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Inflammation grade (G) and fibrosis stage (S) have no correlation with the level of HBV DNA or the state of HBeAg positivity.	17524262
Hepatic inflammation	Altered Intercellular Communication	The increased level of PCIII might be related to their hepatic inflammation.	17524262
Fibrosis Assessment, Necrosis with inflammation	Altered Intercellular Communication	Grades of liver necrosis/inflammation and fibrosis were compared between the patients regarding their HBV DNA positivity or negativity.	17524263
Fibrosis Assessment, Necrosis with inflammation	Altered Intercellular Communication	The grades of liver necrosis/inflammation and fibrosis were compared between three age groups: younger than 18 years, 18-40, and older than 40 years.	17524263
Fibrosis Assessment, Necrosis with inflammation	Altered Intercellular Communication	There were no significant differences in the grades of liver necrosis/inflammation and fibrosis between the chronic HBV carriers and the inactive HBsAg carriers.	17524263
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	However, no statistically significant differences in degrees of liver inflammation and fibrosis were found among the three age groups.	17524263
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	The majority of our HBV carriers have liver inflammation and fibrosis.	17524263
Inflammation	Altered Intercellular Communication	Alterations in circulating levels of pro- and anti-inflammatory cytokines and cell adhesion molecules during sleep deprivation were consistent with both increased and decreased inflammation.	17524614
Inflammation	Altered Intercellular Communication	Physical examination revealed an impressive knee joint effusion with no signs of inflammation.	17525717
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The relationship between airway structural changes and inflammation is unclear in early cystic fibrosis (CF) lung disease.	17526676
Inflammation, Blood Clot	Altered Intercellular Communication	Histopathology showed thrombi and eosinophilic inflammation of arteries.	17527042
Inflammation	Altered Intercellular Communication	These lesions could be reactive in nature, perhaps secondary to chronic inflammation or a neoplastic process that lack specific genetic alterations.	17527084
Fatty degeneration, Hepatitis	Altered Intercellular Communication	Liver inflammation, HCV genotype 3, and BMI are associated with steatosis, a common finding in HCV-HIV-coinfected patients.	17527092
Endometriosis	Altered Intercellular Communication	Endometriosis is the presence of ectopic endometrial tissue that responds to hormonal stimulation.	17530117
ARCN1 gene, Inflammation	Altered Intercellular Communication	Insulin resistance and inflammation - A further systemic complication of COPD.	17530505
ARCN1 gene, Inflammation	Altered Intercellular Communication	We assessed the association between systemic inflammation and insulin resistance in non-hypoxaemic patients with COPD.	17530505
ARCN1 gene, Inflammation	Altered Intercellular Communication	We demonstrated greater insulin resistance in non-hypoxaemic patients with COPD compared with healthy subjects, which was related to systemic inflammation.	17530505
Inflammation, Rheumatic Fever	Altered Intercellular Communication	Inflammatory rheumatic disease and smoking are predictors of aortic inflammation: a controlled study of biopsy specimens obtained at coronary artery surgery.	17530648
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis may result from systemic and/or local vascular inflammation.	17530648
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	The frequency of atherosclerotic lesions, inflammation within the plaques, and epicardial inflammatory infiltrates in the 2 groups was equal.	17530648
Inflammation, Autoimmune reaction	Altered Intercellular Communication	These findings indicate that as neutrophils enter the site of inflammation, they release surface-expressed BLyS in a TNFalpha-dependent manner, and thus may contribute to local stimulation of autoimmune B cell responses.	17530706
Inflammation	Altered Intercellular Communication	The histology is that of moderate to marked, nonspecific chronic inflammation.	17532096
Granulomatous inflammation, Tuberculosis, Necrosis	Altered Intercellular Communication	Thyroid is a rare localization of tuberculosis, and should be considered in the diagnosis of nodular lesion of the thyroid gland except for the complicated forms with collection in which the fine needle aspiration showed the acid fast bacilli on Ziehl-Neelson stain (Koch bacilli) and/or granulomatous inflammation with caseation necrosis.	17532284
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Histological examination of a laparoscopic liver biopsy specimen showed moderate fibrosis limited to portal tracts without necrosis or inflammation.	17533029
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	The prevalence of inflammation is high among patients with chronic heart failure (CHF).	17533522
Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis	Altered Intercellular Communication	Inflammatory bowel diseases, Crohn's disease (CD) and ulcerative colitis are characterised by chronic transmural, segmental and typically granulomatous inflammation of the gut.	17534574
Inflammation, Necrosis	Altered Intercellular Communication	Rapid removal of apoptotic cells is critical for tissue homeostasis, in order to avoid accumulation of necrotic material and subsequent inflammation in the pathological vascular wall.	17534843
Granulomatous inflammation	Altered Intercellular Communication	Four patients presenting with chronic pigmented purpuric dermatosis (CPPD) on the limbs were found to have granulomatous inflammation superimposed on the pathological changes of CPPD.	17535280
Inflammation, Data types - Address	Altered Intercellular Communication	These data strengthen the evidence for a pathophysiologic role of inflammation in the development of clinical AD.	17536046
Inflammation	Altered Intercellular Communication	The induction of a granulomatous inflammation by jellyfish toxins is rare.	17537043
Granulomatous inflammation	Altered Intercellular Communication	Histological examination revealed a granulomatous inflammation with some eosinophils.	17537043
Airway structure, Bronchial Hyperreactivity	Altered Intercellular Communication	Persistent airway inflammation and bronchial hyperresponsiveness in patients with totally controlled asthma.	17537187
Airway structure, Asthma, Bronchial Hyperreactivity	Altered Intercellular Communication	The results of this study suggest that airway inflammation and bronchial hyperresponsiveness still persisted during total control of asthma.	17537187
palladium, Inflammation	Altered Intercellular Communication	Together, our data suggest an early role for SYN and inflammation in PD pathogenesis.	17537546
Inflammation, Impaired cognition	Altered Intercellular Communication	We tested the hypothesis that elevated serum concentration of high sensitivity C-reactive protein (hs-CRP), an established marker of low-grade inflammation, predicts cognitive impairment in elderly women.	17537742
Respiratory Distress Syndrome, Adult, Inflammation, Severe Acute Respiratory Syndrome	Altered Intercellular Communication	It is not understood how immune inflammation influences the pathogenesis of severe acute respiratory syndrome (SARS).	17537853
Fibrosis Assessment	Altered Intercellular Communication	Histologic activity index (HAI) data were available for 1,304 of these patients: increasing [HCV RNA](BL) correlated with higher fibrosis and necrosis-inflammation scores.	17537941
Peripheral Vascular Diseases, Vascular Stenosis	Altered Intercellular Communication	Peripheral arterial disease (PAD) is a chronic fibroproliferative inflammatory condition associated with progressive vascular stenosis.	17538844
Strongyloidiasis	Altered Intercellular Communication	Syndrome of inappropriate secretion of antidiuretic hormone associated with strongyloidiasis.	17539272
Inflammation, Diabetes Mellitus, Hereditary	Altered Intercellular Communication	Most frequent causes were diabetes mellitus (18%), inflammation, (16%) and hereditary (14%).	17539935
Inflammation, Diabetes Mellitus, Polyneuropathy, Hereditary	Altered Intercellular Communication	Symptomatic polyneuropathy was common and diabetes mellitus, inflammation and hereditary were frequent causes.	17539935
Inflammation, Ischemic stroke, Bacterial Endocarditis	Altered Intercellular Communication	A 40-year-old man, smoker with cavitated lesions in both lungs, and inflammation in the nasal mucosa and vocal cords developed an ischemic stroke in the left middle cerebral artery, with the etiological study showing non-bacterial endocarditis.	17539950
Inflammation, Dental Plaque	Altered Intercellular Communication	Relationship between a systemic inflammatory marker, plaque inflammation, and plaque characteristics determined by intravascular optical coherence tomography.	17541021
Inflammation, Ulcer	Altered Intercellular Communication	The vacA s1 cagA+ genotype (high virulence) correlated with the presence of antral IM, a more intense acute inflammation in both antrum and corpus and the formation of ulcer.	17541440
Inflammation	Altered Intercellular Communication	The vacA m1 genotype (high virulence) correlated with a more intense acute inflammation in only the corpus as well as more prominent Russell bodies in the antrum.	17541440
Inflammation	Altered Intercellular Communication	No correlation with the virulence status was found for the type and extent of IM, the intensity of chronic inflammation, the formation of lymphoid follicles and the microbial density.	17541440
Cholesteatoma, Inflammation	Altered Intercellular Communication	Pediatric cholesteatomas demonstrated higher incidence of acute inflammation and more extensive disease relative to those from the adults.	17541620
Cholesteatoma, Aggressive behavior, Inflammation	Altered Intercellular Communication	Thus the observed clinical more aggressive behavior of pediatric cholesteatoma is likely due to other secondary factors such as more intense inflammation, disturbed middle ear ventilation or the diminished calcium salt content of pediatric bone.	17541620
Eosinophilic cystitis	Altered Intercellular Communication	Eosinophilic cystitis is a rare inflammatory condition of the urinary bladder of unknown aetiology and characterized by eosinophilic infiltration of the bladder wall.	17541780
Inflammation	Altered Intercellular Communication	In lean patients inflammation appears to be an important determinant of serum insulin level.	17541791
Crohn Disease, Inflammation, Ulcer	Altered Intercellular Communication	Patients with Crohn's disease may have reduced absorption in the small bowel due to loss of effective surface area secondary to chronic inflammation, ulcerative lesions, or resection.	17542775
Hormone abnormality, Obesity, Testicular Diseases	Altered Intercellular Communication	Risk factors are said to be genetic factors and hormonal abnormalities due to obesity or testicular diseases.	17543123
Inflammation	Altered Intercellular Communication	The decrease of the MTR-Pht after anti-TNF-alpha therapy suggests loss of parenchyma integrity; however, these changes could not be attributed to inflammation or demyelination based on our complementary DWI and MRS data.	17543158
Inflammation, Dental Plaque	Altered Intercellular Communication	Both the ESES and ESS toothbrushes are more effective in removing dental plaque and reducing gingival inflammation than the ADA standard toothbrush.	17544560
Huntingtons Disease Pathway	Altered Intercellular Communication	We therefore analyzed neurotransmitter receptors in symptomatic YAC128 Huntington's disease mice.	17544587
Inflammation, Gastric metaplasia	Altered Intercellular Communication	The degree of acute inflammation, chronic inflammation, cholesterolosis, cholesterol polyp and gastric metaplasia was determined and scored.	17546848
Inflammation, Gastric metaplasia	Altered Intercellular Communication	Cholesterolosis was present in 100 patients (50.3%), followed by gastric metaplasia (27.1%), cholesterol polyp (16.1%) and acute inflammation (9.5%).	17546848
Inflammation, Cholelithiasis	Altered Intercellular Communication	Multivariate analysis showed an association between cholelithiasis and acute and chronic inflammation.	17546848
Inflammation, Atherosclerosis, Diabetes Mellitus	Altered Intercellular Communication	Inflammation and oxidative stress cause genesis and progression of atherosclerosis in diabetes.	17548203
Inflammation, Biliary calculi, Gallbladder and bile duct calculi, Stenosis, Bile duct calculus	Altered Intercellular Communication	There were 44 patients with intraduodenal peri-ampullary diverticulum in 81 patients with primary bile duct pigment stones (54.32%), 4 in 8 patients with bile duct stones and gallbladder stones (50%), 7 in 33 patients with bile duct stones secondary to gallbladder stones (21.21%), 3 in 21 patients with inflammation and stricture of the end of the bile duct and papilla (14.29%), 1 in 22 patients with carcinoma of the end of the bile duct and papilla (4.54%), and 5 in 13 patients with post-cholecystectomy syndrome or sphincter of Oddi dysfunction (38.46%).	17548255
Bile duct calculus, Inflammation, Stenosis, Biliary calculi	Altered Intercellular Communication	The incidence rate of intraduodenal peri-ampullary diverticulum in patients with primary bile duct pigment stones is higher than that in patients with bile duct stones secondary to gallbladder stones, patients with inflammation and stricture of the end of the bile duct and papilla, and patients with carcinoma of the end of the bile duct and papilla.	17548255
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Oxidative stress, associated with aging and inflammation, is likely to play a role in the etiology of prostate cancer.	17548672
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Inflammation is associated with worse prognosis and survival in many cancers.	17548678
Autistic Disorder, Large head (disorder), Neurodevelopmental Disorders	Altered Intercellular Communication	Autism is a heritable neurodevelopmental disorder characterized biologically by enlargement of the head and brain and abnormalities of serotonin neurotransmission.	17548752
Inflammation, Meningioma of optic nerve sheath	Altered Intercellular Communication	Clinical without histopathological manifestations of inflammation in a patient with primary intraorbital optic nerve sheath meningioma.	17548993
Inflammation, Neoplasms	Altered Intercellular Communication	Debulking of the tumor 11 years after the original surgery again revealed no pathologic signs of inflammation.	17548993
Meningioma of optic nerve sheath, Orbital Pseudotumor	Altered Intercellular Communication	Our case affirms that primary optic nerve meningiomas may rarely cause episodic manifestations resembling those of idiopathic orbital inflammation that resolve with corticosteroid treatment.	17548993
Inflammation, Data types - Address	Altered Intercellular Communication	These results indicate that PGD2 may act as a mediator of plaque-associated inflammation in AD brain and may explain the pharmacologic mechanisms underlying the favorable response of patients with AD to nonsteroidal anti-inflammatory drugs.	17549007
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	One week after beginning systemic application of acyclovir (5 x 800 mg daily) and prednisolone (30 mg daily), the anterior chamber inflammation regressed and a fibrosis seemed to appear in the atrophic scleral area.	17549494
Inflammation, Atherosclerosis	Altered Intercellular Communication	It lends support to the importance of inflammation in atherosclerosis and suggests that autoimmune processes may be involved.	17550930
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Chronic inflammation is hypothesized to be associated with breast cancer development.	17551149
Inflammation, Weight decreased, Cardiovascular Diseases	Altered Intercellular Communication	This suggests that weight loss or other interventions targeted at adipocyte-related inflammation may represent an important means to prevent subclinical inflammation in the elderly, bearing a high risk of cardiovascular disease.	17551260
Hair follicle structure, Inflammation, Atrophic, Corneal dystrophy	Altered Intercellular Communication	Keratosis follicularis spinulosa decalvans is a rare, X-linked disorder of keratinization of the hair follicle with inflammation and atrophy associated with corneal dystrophy and other symptoms.	17551700
Refractory anemias, Inflammation	Altered Intercellular Communication	Our study shows a relative deficiency of circulating CysC during systemic inflammation in RA.	17552057
Inflammation, Exanthema	Altered Intercellular Communication	Treatment with etanercept 25 mg twice weekly was followed by remission of the joint inflammation and improvement of the exanthem.	17552060
Inflammation, Pain Distress Question	Altered Intercellular Communication	Suppression of inflammation plays an important role in healing and pain relief.	17552408
Inflammation, Virus Diseases	Altered Intercellular Communication	PCT levels are usually low in viral infections, chronic inflammation or postsurgical states.	17552872
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	FABP4 plasma concentrations are increased with the early presence of MS components, as well as inflammation and oxidation markers in T2D subjects.	17553506
Inflammation, Obesity, Diabetes Mellitus	Altered Intercellular Communication	However, strong coronary risk factors like obesity, diabetes, cigarette smoking and inflammation increase circulating levels of active PLTP.	17553507
Inflammation, Psoriasis	Altered Intercellular Communication	Therefore, we provided early evidence for the important role of IL-15 genetic variants in the pathogenesis of psoriasis, probably by increasing interleukin production and inflammation in the lesions of psoriasis.	17554368
Inflammation, Granulation finding	Altered Intercellular Communication	The false positive PET findings were mainly in the bowel and were secondary to acute/chronic inflammation and granulation tissue.	17555577
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	A rational connection of inflammation with peripheral arterial disease.	17555883
Inflammation, Atherosclerosis	Altered Intercellular Communication	Recently, it has become clear that inflammation is fundamental to the process of atherosclerosis.	17555883
Inflammation, Atherosclerosis	Altered Intercellular Communication	Although the relation between inflammation and PAD is not well characterized, the emerging data demonstrated that PAD is a common manifestation of atherosclerosis that is associated with a systemic inflammation.	17555883
Inflammation	Altered Intercellular Communication	In the general United States adult population, inflammation is independently associated with PAD in a cross-sectional, nationally large representative sample.	17555883
Inflammation, Atherosclerosis	Altered Intercellular Communication	All of those evidences indicate that PAD is one aspect of atherosclerosis, a disease rationally connects with inflammation, which may further change our preventive and therapeutic strategies.	17555883
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	To the extent that this proclivity toward inflammation persists over one's lifespan it could explain the heightened incidence of respiratory and cardiovascular disease in low SES populations.	17556642
Communicable Diseases, Inflammation	Altered Intercellular Communication	It has recently been shown that oxidative stress, infection, and inflammation are predominant pathophysiologic factors for several major diseases.	17556700
Inflammation, Communicable Diseases, Idiopathic Interstitial Pneumonias, Lung Diseases, Interstitial, Undifferentiated Connective Tissue Diseases, Connective Tissue Diseases	Altered Intercellular Communication	We studied 28 consecutive patients with idiopathic interstitial pneumonia (IIP) enrolled in the University of California, San Francisco Interstitial Lung Disease Center who met prespecified criteria for UCTD, as follows: at least one clinical manifestation of connective tissue disease, serologic evidence of systemic inflammation in the absence of clinical infection, and absence of sufficient American College of Rheumatology criteria for another connective tissue disease.	17556720
Carcinoid tumor of lung, Cushing Syndrome	Altered Intercellular Communication	In vivo response to growth hormone-releasing peptide-6 in adrenocorticotropin-dependent Cushing's syndrome by lung carcinoid tumor is associated with growth hormone secretagogue receptor type 1a mRNA expression.	17556872
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Airway inflammation in chronic obstructive pulmonary disease (COPD) is characterised by infiltration of CD8+ T cells and CD68+ macrophages and an increased number of neutrophils, whereas few studies have described the presence of eosinophils.	17557771
Inflammation	Altered Intercellular Communication	Evidence supports the idea that TNF plays a role in chronic inflammation and migration of neutrophils to these lesions.	17558009
Inflammation	Altered Intercellular Communication	Histopathology of cutaneous and nasopharyngeal lesions revealed numerous thick walled sporangia in a vascular connective tissue along with a granulomatous inflammation confirming the diagnosis of cutaneous and nasopharyngeal rhinosporidiosis.	17558051
Communicable Diseases, Inflammation	Altered Intercellular Communication	In conclusion, sTREM-1 and PCT are not specific for infection and can increase markedly in acute inflammation without infection.	17558349
Myositis	Altered Intercellular Communication	Because calsequestrin is an intracellular protein, the corresponding autoantibodies probably do not initiate LPS muscle inflammation but may contribute to its damage.	17558832
Inflammation	Altered Intercellular Communication	This case describes a unique presentation of conjunctival involvement in CSS that differs from prior case reports by having a small, well-demarcated nodule and lacking signs of active inflammation.	17558836
Inflammation	Altered Intercellular Communication	Association between gallstone-evoked pain, inflammation and proliferation of nerves in the gallbladder: a possible explanation for clinical differences.	17558913
Inflammation, Biliary calculi	Altered Intercellular Communication	Nerve growth alteration may play a role in uncomplicated gallstone pain but the pathology may be different in inflammation.	17558913
Cessation of life, Periodontal Diseases	Altered Intercellular Communication	Growing experimental evidence implicates chronic inflammation/infection due to periodontal diseases as a risk factor for death.	17559634
Gingivitis, Periodontitis, Calculi, Dental Plaque	Altered Intercellular Communication	In Group A significant differences were present at baseline between survivors and persons who later died, with respect to dental plaque, calculus, gingival inflammation and number of missing molars in subjects with periodontitis (p < 0.001).	17559634
Inflammation, Arthritis, destruction joint	Altered Intercellular Communication	Angiogenesis markers (VEGF, soluble receptor of VEGF and angiopoietin-1) in very early arthritis and their association with inflammation and joint destruction.	17560831
Inflammation, bone destruction, Arthritis	Altered Intercellular Communication	Serum concentrations of VEGF, sFlt-1 and angiopoietin-1 were correlated to parameters of inflammation and to bone destruction in early arthritis.	17560831
Chronic inflammation	Altered Intercellular Communication	She had resection of the lesion which proved to be a ruptured bronchogenic cyst with chronic inflammation.	17561459
Chronic inflammation, Mediastinal Fibrosis	Altered Intercellular Communication	And we further find a ruptured bronchogenic cyst with chronic inflammation as an etiology of fibrosing mediastinitis.	17561459
Meningitis, Bacterial, Inflammation	Altered Intercellular Communication	Fibronectin is elevated in the cerebrospinal fluid of patients suffering from bacterial meningitis and enhances inflammation caused by bacterial products in primary mouse microglial cell cultures.	17561936
Inflammation Mediators	Altered Intercellular Communication	Involvement of the Th1 directed cytokine interferon-gamma has been demonstrated and Th2 directed cytokines such as IL-10 protect against inflammation-mediated degeneration of dopaminergic neurons in the SN.	17562359
Gastrointestinal inflammation	Altered Intercellular Communication	Lactoferrin in stool samples could be a non-invasive marker of GI inflammation during RT.	17562440
Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	Four patients with prolonged preoperative inflammation and ulceration at KPro placement had resolution of inflammation within days.	17562983
Inflammation, Impaired cognition, Metabolic Syndrome X	Altered Intercellular Communication	Recent evidence suggests that the metabolic syndrome and inflammation affect cognitive decline in old age and that they reinforce each other.	17563341
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	There was a significant interaction between metabolic syndrome and inflammation on cognition (P < 0.01-0.09).	17563341
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome was negatively associated with cognition in subjects with high inflammation (highest tertile for both CRP and ACT; B values ranging from -0.86 to -1.94, P < 0.05), whereas an association was absent in subjects with low inflammation (B values ranging from -0.10 to -0.70).	17563341
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Subjects with metabolic syndrome showed poorer cognitive performance than subjects without metabolic syndrome, especially those with high levels of inflammation.	17563341
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	This patient is still followed up under low dose steroids and pulmonary findings regressed but low grade inflammation due to vasculitis is thought to continue as supported by the persistence of tomographic findings in the lungs despite the absence of any symptoms.	17564286
Inflammation, Gastro-esophageal reflux disease with esophagitis, Duodenal Ulcer, Gastric Ulcer, CTCAE 5, Erythema, Duodenitis, Intestinal metaplasia	Altered Intercellular Communication	In the successful eradication group, (1) there was no significant change on endoscopic findings, including gastric erythema and erosion in all three regions irrespective of NSAIDs use; (2) of 17 active ulcers before eradication in NSAIDs users, all healed except for one duodenal ulcer that persisted, where one patient newly developed a gastric ulcer, one developed erosive duodenitis, and two developed reflux esophagitis, all in NSAID users; (3) neutrophil infiltration and chronic inflammation were significantly improved in all three regions after H. pylori eradication irrespective of use of NSAIDs, while atrophic change and intestinal metaplasia did not change.	17564779
Drug-induced, Infiltration, Hyperplasia, Interstitial inflammation	Altered Intercellular Communication	In contrast, the histological findings of transbronchial lung biopsy (TBLB) samples were characterized by the interstitial infiltration of mononuclear cells and hyperplasia of type II alveolar cells, which are the main features of drug-induced interstitial inflammation.	17564786
Nasal inflammation	Altered Intercellular Communication	They appear to have subclinical nasal inflammation that cannot be identified from clinical assessment, nasal symptom scores or rhinomanometry.	17566187
Inflammation, Adenoma, Villous	Altered Intercellular Communication	Histology revealed acute inflammation and a villous adenoma of the appendix.	17566835
Secondary physiologic amenorrhea, Neoplasms	Altered Intercellular Communication	Granulosa cell tumor associated with secondary amenorrhea and serum luteinizing hormone elevation.	17566848
Irregular Menstruation, Menorrhagia, Amenorrhea	Altered Intercellular Communication	Menstrual irregularity, menorrhagia, or even secondary amenorrhea is frequently observed in premenopausal women bearing GCTs with hormonal activity.	17566848
Inflammation, Meningitis	Altered Intercellular Communication	The HSV-2 viral load was significantly higher in primary than in recurrent meningitis and correlated with the degree of inflammation.	17567785
Inflammation	Altered Intercellular Communication	The objective was to explore the hypothesis that arterial carboxyhemoglobin level is associated with inflammation and survival in patients requiring cardiothoracic intensive care.	17568332
Inflammation, Muscle, Smooth, Vascular, Dental Plaque, atherosclerotic	Altered Intercellular Communication	Inflammation and apoptosis of vascular smooth muscle cells in the arterial wall are involved in the atherosclerotic process and destabilization of the plaque.	17568588
Refractory anemias, Rheumatoid Arthritis, Inflammation, Atherosclerosis	Altered Intercellular Communication	Patients with rheumatoid arthritis (RA) have inflammation and increased atherosclerosis.	17570371
Refractory anemias, Inflammation	Altered Intercellular Communication	In conclusion, OPG concentrations are increased in patients with RA and are associated with inflammation.	17570371
Inflammation	Altered Intercellular Communication	Increased expression of CCAAT/enhancer-binding protein beta in proliferative inflammatory atrophy of the prostate: relation with the expression of COX-2, the androgen receptor, and presence of focal chronic inflammation.	17570496
Inflammation	Altered Intercellular Communication	The data demonstrated that chronic inflammation appeared to play roles in the induction of C/EBPbeta expression in prostate epithelium, which was in turn associated with increased COX-2 expression and AR downregulation.	17570496
Xanthogranulomatous inflammation, Inflammatory Myofibroblastic Tumor, Acute inflammation	Altered Intercellular Communication	Fibrohistiocytic inflammatory pseudotumors were characterized by xanthogranulomatous inflammation, multinucleated giant cells, and neutrophilic infiltration, and mostly occurred in the peripheral hepatic parenchyma as mass-forming lesions.	17571078
Inflammation, Venoocclusive disease, Fibrosis Assessment, Waldenstrom Macroglobulinemia, Phlebitis, Cholangitis	Altered Intercellular Communication	In addition, venous occlusion with little inflammation and cholangitis without periductal fibrosis were frequently observed in the fibrohistiocytic type, whereas obliterative phlebitis and cholangitis with periductal fibrosis were common features of the lymphoplasmacytic type.	17571078
Inflammation, Gangrene, Necrosis, Ulcer, Osteomyelitis	Altered Intercellular Communication	There were 22 clinical cases of osteomyelitis, 20 cases of gangrene (including three cases of necrosis without surrounding inflammation), and three cases of pressure ulcer, which were treated by amputation of 24 toes, and resection of 21 metatarsal bones, respectively.	17571217
ARCN1 gene, Inflammation	Altered Intercellular Communication	The result suggests that leptin may play a role in systemic inflammation of COPD.	17572996
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Generalized amyotrophy	Altered Intercellular Communication	Skeletal muscle wasting commonly occurs in patients with chronic obstructive pulmonary disease (COPD) and has been associated with the presence of systemic inflammation.	17573449
Peripheral, Skeletal muscle hypertrophy, Myositis	Altered Intercellular Communication	Pulmonary rehabilitation can induce peripheral muscle adaptations and modifications in factors regulating skeletal muscle hypertrophy and regeneration without decreasing the levels of systemic or local muscle inflammation.	17573449
Pneumothorax	Altered Intercellular Communication	inflammations or pneumothorax, often accompanied by cryosurgical output yet difficult to determine via conventional imaging, could also possibly be diagnosed.	17573622
Communicable Diseases, Inflammation, Infection caused by Helicobacter pylori, Chronic gastritis	Altered Intercellular Communication	The mean fasting serum gastrin concentration was higher in children with both chronic gastritis and H. pylori infection compared with patients without infection or without antral inflammation.	17573842
Airway structure, Asthma	Altered Intercellular Communication	Blood eosinophil numbers and serum levels of eosinophil cationic protein (ECP) are considered as indirect measures of airway inflammation in asthma.	17573858
Airway structure, Asthma	Altered Intercellular Communication	Our results suggest that bronchial responsiveness to AMP is more closely related to airway inflammation, compared with that to methacholine, and support the potential usefulness of AMP challenges in detecting inflammatory changes in young children with asthma.	17573858
Airway structure	Altered Intercellular Communication	Airway inflammation is associated with an increased expression and release of inflammatory reactants that regulate processes of cell migration, activation and degranulation.	17574828
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Increasing scientific data suggest a role for inflammation in chronic heart failure (CHF), but up to now the exact mechanisms are still not clear.	17575327
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	The role of the post-cardioversion time course of hs-CRP levels in clarifying the relationship between inflammation and persistence of atrial fibrillation.	17575330
Inflammation, Atrial Fibrillation by ECG Finding, Cardiac Arrhythmia	Altered Intercellular Communication	Although recent studies suggest that inflammation is involved in the pathogenesis of atrial fibrillation (AF), it remains controversial whether it is a consequence or a cause of the arrhythmia.	17575330
Inflammation, Hypoadiponectinemia, Hypertriglyceridemia, Atherosclerosis	Altered Intercellular Communication	Current findings suggest that relative importance of hypertriglyceridemia and enhanced inflammation, rather than insulin resistance, as the downstream events of hypoadiponectinemia leading to atherosclerosis in the Japanese general population.	17575367
Inflammation, Hematoma, Hemorrhage, Paralytic Ileus, Thermal injury, Injury of bile duct	Altered Intercellular Communication	The complications included bowel thermal injury (consultants [cons], 1; residents [res], none); bile duct injury (cons, 1; res, none); bile leak (cons, 3; res, 5); hemorrhage (cons, 2; res, 2); hematomas at the trocar sites (cons, 5; res, 4); inflammation of the port site at the umbilicus (cons, 4; res, 5); paralytic ileus (cons, 4; res, 3); and hemorrhage from the subxiphoid trocar (cons, 2; res, 3), which stopped spontaneously.	17575762
Communicable Diseases, Inflammation	Altered Intercellular Communication	[Study on the mycoplasma infection status between healthy women and women with gential tract inflammation].	17575931
Inflammation	Altered Intercellular Communication	To study and compare the pathogenicity and pathogenic condition of Ureaplasma urealyticum (Uu) and Mycoplasma homonis (Mh) between healthy women and women with gential tract inflammation.	17575931
Inflammation	Altered Intercellular Communication	1 % in women with gential inflammation, higher than in healthy women whose positive rate was 42.2% (chi(2) = 45.1862, P< 0.0001).	17575931
Inflammation	Altered Intercellular Communication	The result of CCU concentration showed the infected concentration in women with gential tract inflammation was higher than healthy women(Uu: Z = 7.	17575931
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	However, hepatic inflammation and fibrosis score in patients with genotype B were significantly lower than those with genotype C. There were no significantly differences in liver function and HBV-DNA load between patients with genotype B and C, or between patients with sub-type C1 and C2.	17575938
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	Hepatic inflammation and fibrosis score in patients with genotype B were significantly lower than those with genotype C. Genotype C/sub-type C2 were preponderance in northern China.	17575938
Cicatrix, Hypertrophic, Fibrosis Assessment, Inflammation, Dermatologic disorders	Altered Intercellular Communication	Hypertrophic scarring is a skin disorder characterized by persistent inflammation and fibrosis that may occur after wounding or thermal injury.	17576240
Autoimmune Diseases, Dermatomyositis, Myositis	Altered Intercellular Communication	Dermatomyositis is an autoimmune disease that is associated with muscle and skin inflammation.	17576943
Inflammation, Organ Dysfunction Scores, Critical Illness, Systemic Inflammatory Response Syndrome, Blood Coagulation Disorders, Thrombocytopenia	Altered Intercellular Communication	Thus, we evaluated coagulative activity, organ dysfunction, and systemic inflammatory response syndrome (SIRS) in critically ill patients with thrombocytopenia and examined the balance between coagulopathy and systemic inflammation.	17577138
Gastrointestinal inflammation	Altered Intercellular Communication	Fecal M2-pyruvate kinase (M2-PK): a novel marker of intestinal inflammation.	17577247
Inflammatory Bowel Diseases, Inflammation, Ichthyosis Bullosa of Siemens, Irritable Bowel Syndrome	Altered Intercellular Communication	Surrogate markers of bowel inflammation are increasingly being recognized as important, not only as markers of disease activity in inflammatory bowel disease (IBD) but also to differentiate irritable bowel syndrome (IBS) from IBD.	17577247
Pharyngitis	Altered Intercellular Communication	The disease is a multisystem inflammatory condition that develops as a sequel to untreated throat infection by group A beta-hemolytic streptococci.	17578051
Inflammation, Musculoskeletal torsion, function, Autoamputation	Altered Intercellular Communication	These findings suggested autoamputation of the ovary either by inflammation or torsion, which is one of the mechanisms for the formation of an ectopic ovary.	17578369
Inflammation, Chronic Obstructive Airway Disease, Pneumocystis jiroveci	Altered Intercellular Communication	Systemic inflammation in patients with chronic obstructive pulmonary disease who are colonized with Pneumocystis jiroveci.	17578770
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Inflammation is a recognised risk factor for the vulnerable atherosclerotic plaque.	17578854
Inflammation, Stomach Carcinoma, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Role of Helicobacter pylori infection and chronic inflammation in gastric cancer in the cardia.	17578895
Inflammation	Altered Intercellular Communication	Recently, we reported that H. pylori is an important factor for the induction of cardiac inflammation.	17578895
Inflammation	Altered Intercellular Communication	Cardiac inflammation was evaluated at 1 cm distal from SCJ in lesser curvature.	17578895
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The cardiac inflammation was examined in 30 patients (26 with H. pylori and four without H. pylori infection) and we found cardiac inflammation was present in all cases with H. pylori infection.	17578895
Inflammation, Fatigue	Altered Intercellular Communication	; 11.4%), acute inflammation of the adenomatous nodes (7.4%), cold (6.7%), spicy food (5.5%), flebitis of the hemorrhoidal veins (5.5%), fatigue (5.1%), emotional stress (3.9%), forced urine retention (3.1%), bed rest (2.8%), sexual excesses (2%), surgical interventions (2%), etc.	17580384
allergic inflammation, Overactive Bladder	Altered Intercellular Communication	[Allergic inflammation as one of the factors of pathogenesis of overactive urinary bladder].	17580385
allergic inflammation, Hyperplasia	Altered Intercellular Communication	Allergic inflammation with involvement of mast cells, parasympathetic element hyperplasia, ultrastructural changes of myocytes with structural damage to mitochondria were detected in the detrusor of patients with both obstructive and idiopathic OAB.	17580385
Hashimoto Disease, Inflammation, Thyroiditis, Hypothyroidism	Altered Intercellular Communication	A tissue diagnosis consistent with chronic inflammation (lymphocytic thyroiditis or Hashimoto's thyroiditis) was found in 50.0% of the hypothyroid patients, compared with only 6.8% of the euthyroid patients-again, a significant difference (p < 0.001).	17580812
Chronic inflammation	Altered Intercellular Communication	Apparent risk factors include a high mean preoperative serum TSH level and tissue pathology consistent with chronic inflammation.	17580812
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	The effects of protease-activated receptor-2 (PAR-2) stimulation on inflammation mechanisms of chronic rhinosinusitis (CRS) are still unknown.	17581194
Airway structure, airway disease	Altered Intercellular Communication	Airway inflammation using sputum cell counts has not been assessed in obese patients with airway diseases.	17581198
Airway structure, Asthma	Altered Intercellular Communication	In this large sample of adult asthmatic and non-asthmatic participants, there was no association between BMI and airway inflammation measured by sputum cell counts.	17581198
Inflammation, Septic Shock	Altered Intercellular Communication	We may hypothesize that given its potent inhibitory properties and its association with survival, human leukocyte antigen-G5 has an important role in the numerous negative feedback signals that limit the process of inflammation during septic shock.	17581490
Tumor necrosis, Dermatitis	Altered Intercellular Communication	Tumour necrosis factor-alpha and interleukin-1beta were further used in an in vivo model of skin inflammation; interleukin-1beta alone modulated claudin protein expression in this system.	17582238
Inflammation, Meningitis, Osteogenesis, Fibrous, Deafness	Altered Intercellular Communication	Meningitis may cause inflammation of the cochlea, which may result in deafness and also in rapid obliteration ofthe cochlea with fibrous tissue or even ossification, conditions that obstruct the placement ofa cochlear implant.	17583085
Inflammation, myocardial injury	Altered Intercellular Communication	Difference in humoral biomarkers for myocardial injury and inflammation in radiofrequency ablation versus cryoablation.	17584270
Inflammation, myocardial injury	Altered Intercellular Communication	Markers of myocardial injury and inflammation have been shown to be elevated following radiofrequency (RF) ablation.	17584270
Inflammation, myocardial injury	Altered Intercellular Communication	This study aimed to compare RF ablation and cryoablation for their impact on markers for myocardial injury and inflammation.	17584270
Inflammation, myocardial injury	Altered Intercellular Communication	We show reduced inflammation despite higher markers for myocardial injury in cryoablation.	17584270
Inflammation, Allergic, Hypersensitivity, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	Brain-derived neurotrophic factor (BDNF) has been described to modulate airway hyper-responsiveness and inflammation and was involved in late allergic reaction in asthma and higher levels of circulating BDNF were present in allergic asthmatics.	17584309
Adenocarcinoma, Endometriosis of uterus	Altered Intercellular Communication	Adenocarcinoma in adenomyosis may be affected by local hormonal influence and, despite its small size, may metastasize.	17584489
Acute and chronic inflammation	Altered Intercellular Communication	Altogether, these findings indicate that genes participating in IL23 signalling play a significant role in the pathogenesis of chronic epithelial inflammation.	17587057
Lesion, Inflammation	Altered Intercellular Communication	Differences between the groups regarding decayed, missed, or filled surfaces, decayed surfaces, initial caries lesions, and gingival inflammation were non-significant.	17587293
Airway structure, Asthma, Atopy	Altered Intercellular Communication	This study examined the prevalence of asymptomatic BHR in a population of young Japanese atopic individuals to identify whether airway inflammation is present in asthmatic patients but not in asymptomatic subjects with BHR.	17587418
Airway structure, Asthma, Atopy	Altered Intercellular Communication	In young adult atopic subjects with asymptomatic BHR, airway inflammation does not necessarily play a determining role in the development of BHR to methacholine itself, though it might be an important factor in the onset of asthma.	17587418
Inflammation, Coronary Artery Vasospasm	Altered Intercellular Communication	Coronary spasm is associated with chronic low-grade inflammation.	17587713
Inflammation, Coronary Artery Vasospasm, Myocardial Ischemia	Altered Intercellular Communication	Coronary spasm plays an important role in the pathogenesis of ischemic heart disease and it may be associated with low-grade inflammation.	17587713
Inflammation, Coronary Artery Vasospasm	Altered Intercellular Communication	Minor elevations of the serum hs-CRP level are significantly associated with coronary spasm, suggesting that chronic low-grade inflammation may be involved in the pathogenesis of coronary spasm.	17587713
Inflammation, Apolipoprotein E, Thrombosis, Atherosclerosis	Altered Intercellular Communication	We therefore investigated spontaneous atherosclerosis and atherothrombosis, and systemic markers of inflammation (acute phase proteins), in aged, normal diet-fed, male apolipoprotein E deficient (apoE(-/-)) mice with and without transgenic expression of human CRP.	17588586
Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Mediastinoscopic biopsy and skin biopsy showed non-caseating granulomatous inflammation.	17588845
Sepsis, Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Activated protein C (PC) is a critical endogenous regulator of coagulation and inflammation in patients with sepsis.	17589380
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation has been implicated in the pathophysiology of a series of cardiovascular diseases.	17589635
Inflammation	Altered Intercellular Communication	CRP is an independent cardiovascular mortality predictor in patients with ADHF, indicating that inflammation represents an important component in the pathophysiology of the disease.	17589635
Arthralgia, Inflammation	Altered Intercellular Communication	The patient with benign joint hipermobility can develop symptoms such as arthralgia caused by a joint inflammation.	17589715
Intestinal metaplasia, Inflammation, Neoplasms	Altered Intercellular Communication	It may be suggested that induction of apoptosis in intestinal metaplasia areas adjacent to tumors may involve different mechanisms than induction by chronic inflammation.	17589896
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	These observations suggest that increased expression of mucosal SOCS3, but not of SOCS1, may play a critical role in the development of the colonic inflammation of UC.	17589943
Inflammation, Mucous Membrane	Altered Intercellular Communication	The specimens were evaluated for the severity of acute and chronic inflammation and for that of mucosal atrophy, based on the updated Sydney system.	17591044
Inflammation, Mucous Membrane	Altered Intercellular Communication	There was a significant decrease in the acute and chronic inflammation scores and also in the mucosal atrophy score following the eradication.	17591044
Inflammation, Postoperative ileus	Altered Intercellular Communication	Intestinal handling-induced mast cell activation and inflammation in human postoperative ileus.	17591620
Postoperative ileus, Gastrointestinal inflammation	Altered Intercellular Communication	Murine postoperative ileus results from intestinal inflammation triggered by manipulation-induced mast cell activation.	17591620
Inflammation, Humor, Uveitis	Altered Intercellular Communication	Our present observations suggest that aqueous humor levels of ADMA may be a novel biomarker of inflammation in uveitis.	17591667
Infection	Altered Intercellular Communication	To examine the association of single nucleotide polymorphisms (SNPs) in inflammation-related genes in the development of infections following esophagectomy.	17592300
Keratitis	Altered Intercellular Communication	MRSA was grown in a cultured test, and topical and systemic vancomycin was applied and resolved the corneoscleral inflammation.	17592329
vascular inflammations, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	These observations suggest the possibility that sRAGE level may become a novel biomarker of vascular inflammation in type 2 diabetic patients.	17592553
Inflammation, Tissue injury, MS gene	Altered Intercellular Communication	Antibody-mediated inflammation is believed to contribute to tissue injury in multiple sclerosis (MS).	17594338
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In the 36 HBeAg-negative patients the respective number of cases with inflammation scores of G1, G2, G3 and G4 were 5, 14, 15, 2, and with fibrosis scores of S1, S2, S3, S4 were 8, 12, 6, 10.	17594807
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Although histopathological inflammation and fibrosis scores had no statistical difference between HBeAg-negative and positive patients (P > 0.05), 53.2% patients of HBeAg-negative group and 44.5% patients of HBeAg-positive group had a fibrosis score of >or= S3.	17594807
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	The role of tumor associated macrophages (TAMs) in tumor angiogenesis and inflammation and the interactions between TAMs and tumor cells as well as lymphocytes appear to be critical factors in the development and progression of cancer.	17595799
Osteomyelitis	Altered Intercellular Communication	Users of intravenous bisphosphonates had an increased risk of inflammatory conditions, osteomyelitis, and surgical procedures of the jaw and facial bones.	17596574
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Systematic evaluation of genetic variants in the inflammation pathway and risk of lung cancer.	17596594
Inflammation, Carcinoma of lung	Altered Intercellular Communication	To test this hypothesis, we studied genetic polymorphisms in the inflammation pathway in relation to lung cancer risk.	17596594
Aciduria, Inflammation, Fever, CTCAE, Cerebellar Ataxia	Altered Intercellular Communication	Mevalonic aciduria is a rare, inborn error of isoprene biosynthesis characterized by severe, periodic attacks of fever and inflammation, developmental delay, ataxia, and dysmorphic features.	17596604
Inflammation, Attack behavior	Altered Intercellular Communication	We observed sustained remission of febrile attacks and inflammation during a 15-month follow-up period.	17596604
Intraocular inflammation	Altered Intercellular Communication	Nevertheless, patients who received Densiron 68 twice due to redetachment showed a significantly higher rate of intraocular inflammation with the tamponade agent in situ.	17596752
Inflammation, Infectious Otitis Media	Altered Intercellular Communication	When compared with children who have unilateral AOM, children with bilateral AOM were more likely to be younger (P < 0.001), have H. influenzae isolated from one or both MEFs (P < 0.0001), and have more severe inflammation of the tympanic membrane on otoscopic examination (P < 0.0001).	17596798
Inflammation, Infectious Otitis Media	Altered Intercellular Communication	Compared with children who have unilateral AOM, children with bilateral AOM are more likely to have bacteria in the MEF and have more severe inflammation of the tympanic membrane.	17596798
Inflammation, Inflammatory Hepatocellular Adenoma	Altered Intercellular Communication	Telangiectatic adenoma: an entity associated with increased body mass index and inflammation.	17596890
Inflammation, Dysplasia	Altered Intercellular Communication	The brother, who was 14 years old, had similar manifestations without laboratory evidence of inflammation; radiographs disclosed dysplasia of the hips and metacarpophalangeal epiphyses.	17596985
Inflammation	Altered Intercellular Communication	Elevated interleukin (IL)-6 and C-reactive protein (CRP) levels in patients with AF suggest a role of inflammation in the pathogenesis of AF.	17597037
Arterial Stiffness, Inflammation	Altered Intercellular Communication	Increased arterial stiffness and wave reflections in RTR are attributable to incomplete restoration of GFR and the presence of subclinical inflammation.	17597092
Inflammation	Altered Intercellular Communication	The study suggests an important molecular mechanism by GMGHT to reduce inflammation, which might explain its beneficial effect in the regulation of inflammatory reactions.	17597500
Hypercholesterolemia, vascular inflammations, Hypertension, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	Pulse wave velocity (PWV) and augmentation index (AIx) have been found to be elevated in patients with vascular inflammation, diabetes mellitus, hypertension, hypercholesterolemia and in smokers.	17597799
Inflammation, Aortic Stiffness, Atherosclerosis	Altered Intercellular Communication	In summary, low-grade inflammation seems to be independently related to increase of aortic artery stiffness over and above traditional risk factors and atherosclerosis.	17597799
allergic inflammation, Bronchitis	Altered Intercellular Communication	Due to diagnostic difficulties in this age group allergic inflammation markers are taken into consideration in aspect of recurrent bronchitis prevention.	17598659
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	Resistin is an adipokine that has been suggested to be correlated with markers of inflammation and to be predictive of coronary atherosclerosis and type II diabetes in humans.	17598818
Inflammation	Altered Intercellular Communication	Haptoglobin is a glycoprotein involved in the acute-phase response to inflammation, and it is increased in obese subjects.	17598972
Obesity	Altered Intercellular Communication	Obesity is associated with a chronic low-grade inflammatory condition.	17598972
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Thus, anti-aging strategies might complement existing therapeutic targets related to anabolism, catabolism, inflammation, and apoptosis-processes that are integral to the pathogenesis of osteoarthritis.	17599073
Vestibular Neuronitis	Altered Intercellular Communication	Neuroinfection started after late-treated vestibular inflammation, caused by Streptococcus pneumoniae.	17599298
Inflammation	Altered Intercellular Communication	We compared serum markers of oxidation and associated inflammation in individuals with or without AF.	17599958
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Serum markers of oxidative stress and inflammation were compared in a cross-sectional, case-control design study of 40 male individuals, with or without persistent or permanent AF, who were matched for age, sex, diabetes, and smoking status, known confounding variables for the measurement of oxidative stress.	17599958
Hypertensive (finding), Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Hypertensive patients have pathophysiological changes such as atherosclerosis, endothelial dysfunction and inflammations.	17600548
Inflammation, Atherosclerosis	Altered Intercellular Communication	Evidence suggests that atherosclerosis is an inflammatory condition and long chain n-3 fatty acids, found in oily fish and fish oils, have been shown to reduce inflammation.	17600695
Inflammation, Atherosclerosis	Altered Intercellular Communication	Evidence suggests that atherosclerosis is an inflammatory condition and long chain n-3 fatty acids, found in oily fish and fish oils, have been shown to reduce inflammation.	17600695
Inflammation	Altered Intercellular Communication	Levels of LBP, markers of inflammation, and traditional risk factors for CAD were assessed.	17601541
Inflammation	Altered Intercellular Communication	Moreover in multivariable logistic regression analyses, adjusted for established cardiovascular risk factors and markers of systemic inflammation, LBP was a significant and independent predictor of prevalent CAD (p < 0.05 in all models).	17601541
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic disease	Altered Intercellular Communication	Chronic inflammation and microcirculatory disturbances of the skin have been implicated as causative factors of complications associated with chronic venous disease (CVD).	17601858
Inflammation, Sarcocystis, Necrosis	Altered Intercellular Communication	We identified enterovirus in 5 (18.5%) cases and Sarcocystis in a 36-year-old woman who had focal inflammation and myocyte necrosis.	17602724
Encephalitis, Pneumonia, Interstitial, Enterovirus, Myocarditis	Altered Intercellular Communication	Immunohistochemical evidence of enteroviruses was found in the myocytes of 2 patients less than 6 months old who had diffuse mononuclear myocardial inflammation, interstitial pneumonitis; one also had encephalitis.	17602724
Inflammatory Bowel Diseases	Altered Intercellular Communication	Inflammatory bowel disease (IBD) is characterized by chronic intestinal inflammation accompanied by changes in motility.	17602742
Inflammation	Altered Intercellular Communication	These changes in SP receptor expression during chronic inflammation suggest that SP receptors are a potential target for therapeutic regulation of the inflammatory response.	17602742
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Ambient source-specific particles are associated with prolonged repolarization and increased levels of inflammation in male coronary artery disease patients.	17603085
Inflammation	Altered Intercellular Communication	Ambient particulate air pollution has been associated with altered cardiac function and systemic inflammation.	17603085
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	We reported repolarization changes and variations in markers of inflammation in association with ambient particulate exposure in a panel of male coronary artery disease (CAD) patients.	17603085
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Impaired lung function is associated with systemic inflammation and is a risk factor for cardiovascular disease in older adults.	17604302
Inflammation	Altered Intercellular Communication	Reduced lung function is associated with systemic inflammation in young adults.	17604302
Inflammation, Chronic lung disease, Atherosclerosis	Altered Intercellular Communication	The reasons for the association are unexplained, but the findings indicate that the association between lower lung function and increased inflammation predates the development of either chronic lung disease or clinically significant atherosclerosis.	17604302
Nerve palsy, Inflammation	Altered Intercellular Communication	In all of the few cases reported previously, the fixation was caused by mechanical obstruction of vocal cord movement or by recurrent nerve palsy secondary to inflammation.	17606043
Airway structure	Altered Intercellular Communication	We examined changes in the cellular nature of airway inflammation between consecutive exacerbations and their predictors in individual patients.	17606366
Airway structure	Altered Intercellular Communication	The patients were divided into those who demonstrated a change in the type of airway inflammation and those who did not.	17606366
neutrophilic, Inflammation	Altered Intercellular Communication	The cellular nature of inflammation was eosinophilic in 43%, neutrophilic in 40%, combined eosinophilic and neutrophilic in 5% and unclassified in 12%.	17606366
Airway structure	Altered Intercellular Communication	A change in the type of airway inflammation was seen in 38 patients (48%).	17606366
Diabetic Nephropathy	Altered Intercellular Communication	Midkine is involved in tubulointerstitial inflammation associated with diabetic nephropathy.	17607302
Diabetic Nephropathy, Inflammation, Glomerulosclerosis (disorder)	Altered Intercellular Communication	The concept that inflammation plays a crucial role in the pathogenesis of diabetic nephropathy has been recently emerging, although the principal pathology of diabetic nephropathy comprises glomerular sclerosis and associated changes in nephrons.	17607302
Inflammation	Altered Intercellular Communication	Here, we identified the growth factor midkine (MK) as a novel key molecule involved in inflammation associated with Streptozotocin-induced diabetic nephropathy.	17607302
Diabetic Nephropathy	Altered Intercellular Communication	Our data indicate that MK plays a critical role in the tubulointerstitial inflammation associated with diabetic nephropathy through activation of the MCP-1 pathway.	17607302
Refractory anemias, Inflammation	Altered Intercellular Communication	Synovial mast cells produce proinflammmatory cytokines and may thus contribute to the inflammation in RA.	17607547
Nasal Polyps, Nasal inflammation	Altered Intercellular Communication	The evolution of nasal inflammation during a common cold in patients with nasal polyposis under topical steroid treatment is not clearly defined in the literature.	17608135
Inflammation, Ulceration, CTCAE, Colitis	Altered Intercellular Communication	Colonoscopy showed severe ulceration with inflammation suggestive of severe persistent colitis.	17608247
Colitis	Altered Intercellular Communication	Colonic inflammation induces local glucocorticoid activation via 11betaHSD1 and impairs glucocorticoid inactivation via 11betaHSD2.	17608848
Colitis	Altered Intercellular Communication	The observed changes indicate a role for local metabolism of glucocorticoids in the control of colonic inflammation.	17608848
Pneumonitis	Altered Intercellular Communication	These results suggest that proteinases from S. chartarum spores significantly contribute to lung inflammation and injury.	17610048
Autoinflammatory Syndrome, Orbital Pseudotumor	Altered Intercellular Communication	To investigate the expression of multiple therapeutic targets in tissue specimens from patients with orbital inflammatory syndromes, the clinical records of 16 patients treated for orbital inflammation between January 2003 and November 2005 for whom tissue blocks were available were reviewed retrospectively.	17610415
Granuloma, Necrobiotic Xanthogranuloma, Thyroid associated opthalmopathies, Necrotizing granulomatous inflammation, Sarcoidosis, Granulomatosis with polyangiitis, Pseudolymphoma, Orbital Pseudotumor	Altered Intercellular Communication	The histologic diagnoses were as follows: orbital pseudotumor in six patients; sarcoidosis, three; eosinophilic granuloma, one; necrobiotic xanthogranuloma, one; nonspecified granulomatous inflammation, one; Graves' ophthalmopathy, one; Wegener's granulomatosis, one; and reactive lymphoid hyperplasia, two.	17610415
Necrotizing granulomatous inflammation, Granuloma, Granulomatosis with polyangiitis	Altered Intercellular Communication	CD20 was strongly expressed in all specimens except three (Wegener's granulomatosis, eosinophilic granuloma, and nonspecified granulomatous inflammation specimens), and CD25 was strongly expressed in all specimens except the Wegener's granulomatosis specimen, in which this antigen was only moderately expressed.	17610415
Orbital Pseudotumor	Altered Intercellular Communication	CD20 and CD25 were strongly or moderately expressed in most of the tested specimens of orbital inflammation.	17610415
Migraine Disorders, dineopentyl glutamate, Meningitis	Altered Intercellular Communication	Experiments using animal models of dural neurogenic plasma extravasation (DNPE) as an index of meningeal inflammation provided the basis for the meningeal inflammation hypothesis of migraine pain.	17610461
Inflammation	Altered Intercellular Communication	Rare cases of West Nile virus (WNV)-associated inflammation outside the central nervous system (CNS) have been reported.	17610522
Communicable Diseases, Testis, Inflammation	Altered Intercellular Communication	With the exception of testis and brain, most foci of infection were not associated with inflammation.	17610522
Inflammation, Weight decreased, Anemia, Gastrointestinal Hemorrhage	Altered Intercellular Communication	The "plus" symptoms or signs consisted of weight loss (> 10 % of body weight), inflammation shown by laboratory tests, chronic anemia, or suspected mid-gastrointestinal bleeding.	17611915
Inflammation	Altered Intercellular Communication	The additional symptom or sign of inflammation was associated with the highest diagnostic yield (odds ratio 3.2).	17611915
Arthritis	Altered Intercellular Communication	Detection of high levels of 2 specific isoforms of 14-3-3 proteins in synovial fluid from patients with joint inflammation.	17611984
Inflammation, Atherosclerosis, Diabetes Mellitus	Altered Intercellular Communication	Inflammation and oxidative stress are main culprits behind atherosclerosis in diabetes mellitus.	17613279
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	The biopsies were assessed for the presence of mucosal inflammation, activity, eosinophils, atrophy, lymphoid follicles, H. pylori, and the presence of intestinal metaplasia.	17614956
Inflammation, Halitosis	Altered Intercellular Communication	The goals of the dental hygiene care plan included decreasing tension of oral muscles and reducing periodontal inflammation and halitosis.	17615023
Inflammation, Ulcer	Altered Intercellular Communication	The strongest association occurred between biochemical signs of inflammation CRP >10 mg/l, ABI <0.9, ulcer size >5 cm(2), and HRQL on physical functioning (adjusted r(2)=24).	17616352
vascular inflammations, Granulomatosis with polyangiitis	Altered Intercellular Communication	Increased expression of fractalkine (CX3CL1) and its receptor, CX3CR1, in Wegener's granulomatosis--possible role in vascular inflammation.	17616549
Inflammation, Cardiac Death, Autonomic nervous system disorders	Altered Intercellular Communication	The aim of this study was to investigate the relation between low-grade inflammation and autonomic dysfunction, both of which may be risk markers for sudden cardiac death.	17617066
Inflammation, Autonomic nervous system disorders	Altered Intercellular Communication	This may support a link between low-grade inflammation and autonomic dysfunction.	17617066
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Does intraprostatic inflammation have a role in the pathogenesis and progression of benign prostatic hyperplasia?	17617139
Inflammation, Urinary Retention, Lower Urinary Tract Symptoms	Altered Intercellular Communication	To compare the incidence of acute and/or chronic intraprostatic inflammation (ACI) in men undergoing transurethral resection of the prostate (TURP) for urinary retention and lower urinary tract symptoms (LUTS), as recently a role was suggested for ACI in the pathogenesis and progression of BPH, and urinary retention is considered an endpoint in the natural history of this condition.	17617139
Inflammation	Altered Intercellular Communication	Inflammation appears to be important in the pathogenesis and progression of BPH.	17617139
Inflammation, Malnutrition	Altered Intercellular Communication	These findings suggest that non-traditional risk factors, such as inflammation and malnutrition measured during the first 18 months of dialysis, are important determinates of survival in new dialysis patients.	17617651
Inflammation, Endophthalmitis	Altered Intercellular Communication	In the early stage, sympathetic ophthalmia may present only in the posterior segment without any associated anterior segment inflammation and carries a good visual prognosis.	17618240
Inflammation, Atherosclerosis	Altered Intercellular Communication	Fish consumption may be protective against early atherosclerosis in middle-aged men, probably through its beneficial effects on inflammation.	17618950
Inflammation, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The severity of their asthma was related to airflow limitation and eosinophilic inflammation in the peripheral blood, but not to BHR.	17619564
Scleritis	Altered Intercellular Communication	Three patients with scleritis were eventually able to remain inflammation-free while not taking any medication.	17620567
Diarrhea, Gastrointestinal inflammation, HIV Seropositivity	Altered Intercellular Communication	EAEC was significantly associated with diarrhea and intestinal inflammation and was significantly higher (chi(2) = 5.360, P = 0.021) in human immunodeficiency virus (HIV)-positive persons (29.5%) than in HIV-negative persons (13.7%).	17620646
Inflammation, Hypersensitivity	Altered Intercellular Communication	Most of the authors cited local inflammation and hypersensitivity in the vessel wall as the primary etiology.	17620677
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Skin biopsy showed diffuse nonnecrotizing granulomatous inflammation with numerous multinucleated giant cells, lymphocytes, and plasma cells infiltration.	17621750
Inflammation, Aortic Aneurysm, Thoracic	Altered Intercellular Communication	We conclude that patients with thoracic aneurysms have a low-grade inflammation prior to intervention.	17622202
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	Inflammation is considered to be one of the main mechanisms for the development and progression of peripheral arterial disease (PAD).	17622206
Inflammation	Altered Intercellular Communication	During recovery, we found two kinds of response: type 1 (controls and MC), in which inflammation subsides, and type 2 (SC) characterized by further inflammatory increase.	17622206
Aggressive course, Inflammation	Altered Intercellular Communication	This individual inflammatory responsiveness, considering the role of the rest measurement of markers of inflammation recently discussed, could be a useful marker for aggressive PAD.	17622206
Inflammation, Zinc deficiency	Altered Intercellular Communication	MT may sequester zinc during chronic inflammation, provoke zinc deficiency, and modulate NK cell cytotoxicity.	17622311
Inflammation, Necrosis, Panniculitis, Myositis, CTCAE 5.0, Crohn Disease	Altered Intercellular Communication	The CT images were interpreted as an abscess of the thigh, but surgical exploration revealed a diffuse myositis, with panniculitis, necrosis and inflammation of muscle tissue, associated with an exacerbation of Crohn's disease.	17624161
Inflammation	Altered Intercellular Communication	Inflammation is a universal pathological reaction and is characterized among other things by increased heat production.	17624752
Degenerative polyarthritis, ovarian neoplasm	Altered Intercellular Communication	A 59-year-old female with recurrent ovarian cancer received multiple hormonal and cytotoxic regimens for 5 years and then developed erosive osteoarthritis of the hands secondary to BVC and paclitaxel.	17624988
ARCN1 gene, Inflammation, Weight decreased, Hyperdistention	Altered Intercellular Communication	Plasma adiponectin levels in patients with COPD were elevated and correlated with body weight loss, hyperinflation, and systemic inflammation.	17625082
Inflammation, Leukocytosis	Altered Intercellular Communication	Although leukocytosis was observed both in PF and in prostate tissue in all 12 patients, there was no correlation between the leukocyte count in PF and the intensity of inflammation.	17625369
Sepsis, Inflammation	Altered Intercellular Communication	Markers of inflammation, such as C-reactive protein (CRP) and white blood cell count, have, because of their low specificity, proven far from ideal in identifying patients with sepsis.	17625373
Bacterial Infections	Altered Intercellular Communication	Procalcitonin (PCT) has been shown to be a useful marker for differentiating patients with bacterial infection from other acute inflammatory conditions.	17625373
Hepatitis	Altered Intercellular Communication	Low persisting HCV-RNA in patients after antiviral therapy may be associated with mild liver inflammation in single cases.	17625963
Inflammation, Carcinoma	Altered Intercellular Communication	Chronic inflammation of longstanding duration has been linked to the development of carcinoma in several organ systems.	17626652
Inflammation, Primary malignant neoplasm, Adenocarcinoma, Proliferative Inflammatory Atrophy, Atrophic	Altered Intercellular Communication	The objective of our study is to compare on needle prostate biopsies of patients showing cancer the topographical relation of inflammatory atrophy and atrophy with no inflammation to adenocarcinoma.	17626652
Adenocarcinoma, Inflammation, Atrophic, Proliferative Inflammatory Atrophy	Altered Intercellular Communication	Considering only cores showing adenocarcinoma, atrophy was seen in 116/172 (67.44%) biopsies; 70/116 (60.34%) biopsies showed atrophy and no inflammation and 46/116 (39.66%) biopsies showed inflammatory atrophy.	17626652
Proliferative Inflammatory Atrophy, Inflammation, Atrophic	Altered Intercellular Communication	From a total of 481 cores in 72 biopsies with inflammatory atrophy 184/481 (38.25%) cores showed no atrophy; 166/481 (34.51%) cores showed atrophy and no inflammation; 111/481 (23.08%) cores showed both lesions; and 20/481 (4.16%) showed only inflammatory atrophy.	17626652
Inflammation, Urethra, Hypospadias	Altered Intercellular Communication	Meatal stenosis usually presents in adults with a history of urethral trauma or inflammation or as a complication after hypospadias repair.	17627160
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	It might thus be important in the pathogenesis of inflammation associated with coronary artery disease (CAD).	17627181
Inflammation	Altered Intercellular Communication	It seems that moderately increased levels of TIMP-1 could reflect degree of activity of skin inflammation, whereas markedly increased levels could contribute to the maintenance of the remission of disease.	17627649
Abnormal renal function, Inflammation	Altered Intercellular Communication	We evaluated the extent to which the relationship between haemoglobin and N-terminal pro-B-type natriuretic peptide (NT-proBNP) was explained by differences in cardiovascular risk factors, inflammation, and kidney dysfunction.	17627881
Inflammation, Coronary Arteriosclerosis, Anemia	Altered Intercellular Communication	The relationship between anaemia and NT-proBNP is largely explained by differences in cardiovascular risk factors, ventricular function, myocardial ischaemia, inflammation, and kidney function.	17627881
Master of Electrical Engineering, Global systolic dysfunction, Inflammation, Congestive heart failure	Altered Intercellular Communication	We sought to investigate prognostic implications of the relationships of estimated left ventricular (LV) myocardial energy expenditure (MEE) with LV systolic dysfunction, body composition, and inflammation in a population-based sample of adults without overt congestive heart failure.	17628407
Mitochondrial Damage, Inflammation	Altered Intercellular Communication	The muscle biopsy revealed toxic vacuolization, mitochondrial damage, and no evidence of inflammation.	17628739
Cholestasis, Pruritus	Altered Intercellular Communication	Increased central opioidergic neurotransmission, mediated by endogenous opioid peptide agonists, contributes to the pruritus of cholestasis.	17629069
Chronic liver disease, Pruritus	Altered Intercellular Communication	The findings suggest that serotoninergic neurotransmission, in neurons bearing receptors of the 5-HT3 subtype, plays no more than a minor role in the mediation of pruritus complicating chronic liver disease.	17629069
Inflammation, Acquired Immunodeficiency Syndrome	Altered Intercellular Communication	The inflammatory infiltrate found in the AIDS patients was more accentuated and predominantly composed of monocytes, which is characteristic of chronic inflammation.	17630109
Inflammation, Intervertebral Disc Degeneration, Hernia	Altered Intercellular Communication	It has been hypo-thesized a role of biochemical mediators of inflammation and tissue degradation in intervertebral disc degeneration and herniation.	17631744
Inflammation, Intervertebral Disc Degeneration	Altered Intercellular Communication	It may contribute to better clarify the role of this protein in the pathophysiology of discal degeneration and inflammation as confirmed by its relationships with COX-2 and NO in disc tissue culture.	17631744
Inflammation, prostatitis	Altered Intercellular Communication	Examination of the relationship between symptoms of prostatitis and histological inflammation: baseline data from the REDUCE chemoprevention trial.	17632164
Pelvic Pain, prostatitis	Altered Intercellular Communication	Symptoms of abacterial chronic prostatitis/chronic pelvic pain syndrome are considered to be associated with prostate inflammation.	17632164
prostatitis	Altered Intercellular Communication	All men underwent biopsy before study entry, allowing review of the relationship between histological prostate inflammation and prostatitis symptoms.	17632164
Inflammation	Altered Intercellular Communication	The distribution of inflammation status was similar for those with and without chronic prostatitis-like symptoms.	17632164
Inflammation, Prostate carcinoma, prostatitis	Altered Intercellular Communication	A lack of clinically meaningful association was found between prostatitis-like pain symptoms and histological inflammation in the Reduction by Dutasteride of Prostate Cancer Events population, suggesting that the view that symptoms of chronic prostatitis/chronic pelvic pain syndrome and prostate inflammation are associated needs further scrutiny.	17632164
Sepsis, Inflammation, Septic Shock	Altered Intercellular Communication	Procalcitonin was measured at admission (T0) and again 12 hours later (T12h), and the results classed as: < 0.5 ng/mL = sepsis unlikely; >/= 0.5 to < 2 = sepsis possible; >/= 2 to < 10 = systemic inflammation and >/= 10 = septic shock.	17632669
Inflammation, Postoperative Complications, Malignant neoplasm of abdomen	Altered Intercellular Communication	Perioperative administration of an immunoenriched diet significantly reduces systemic perioperative inflammation and postoperative complications in patients undergoing major abdominal cancer surgery, when compared with postoperative diet administration alone.	17632760
Diplopia, Bone Marrow Diseases, Inflammation, Communicable Diseases	Altered Intercellular Communication	These findings suggest that the myelopathy and diplopia were induced by a secondary immune reaction after inflammation caused by EBV infection.	17633108
Inflammation	Altered Intercellular Communication	As majority of them are glycoproteins alterations in glycosylations profiles form additional sign of disturbances in the cytokines network during inflammation and allow to distinguish between acute and chronic inflammatory conditions.	17633395
Inflammation	Altered Intercellular Communication	As majority of them are glycoproteins alterations in glycosylations profiles form additional sign of disturbances in the cytokines network during inflammation and allow to distinguish between acute and chronic inflammatory conditions.	17633395
Inflammation	Altered Intercellular Communication	Neither communication with the frontal sinus nor mucosa with inflammation were seen.	17633512
Inflammation, Inflammatory disorder of cartilage	Altered Intercellular Communication	Relapsing chondritis often causes inflammation of the tracheal cartilages, leading to fragile trachea and bronchus.	17633847
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Chronic inflammation has been identified as an important component of the metabolic syndrome (MetS).	17634253
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	These results suggested that IL1beta genetic variants were associated with measures of chronic inflammation and the MetS risk, and that genetic influences were more evident among subjects with low (n-3) PUFA intake.	17634253
Intraocular inflammation	Altered Intercellular Communication	Trypan blue may be associated with severe intraocular inflammation.	17634862
AURKAIP1 gene, Autoimmune Pancreatitis, Waldenstrom Macroglobulinemia	Altered Intercellular Communication	Autoimmune pancreatitis (AIP) is characterized by high serum immunoglobin (Ig) G4 concentrations, lymphoplasmacytic inflammation, and a favorable response to corticosteroid treatment.	17634963
Inflammation, Lobe of liver, Hepatitis, Canalicular cholestasis, Sclerosis, AURKAIP1 gene	Altered Intercellular Communication	The liver histology of AIP was classified into 5 patterns: evident portal inflammation with or without interface hepatitis (6 cases), large bile-duct obstructive features (8 cases), portal sclerosis (8 cases), lobular hepatitis (5 cases), and canalicular cholestasis (4 cases); some of the histological features coexisted in the same liver.	17634963
Inflammation, Hypertension, CTCAE, Ventricular hypertrophy, Corneal Endothelial Cell Loss	Altered Intercellular Communication	Relation of left ventricular hypertrophy with systemic inflammation and endothelial damage in resistant hypertension.	17635853
Left Ventricular Hypertrophy, Inflammation	Altered Intercellular Communication	The relation between left ventricular hypertrophy (LVH) and unfavorable cardiovascular prognosis may involve systemic inflammation and endothelial dysfunction/damage.	17635853
Inflammation, Left Ventricular Hypertrophy, Corneal Endothelial Cell Loss	Altered Intercellular Communication	In conclusion, both systemic inflammation and endothelial damage were associated with LVH occurrence.	17635853
Inflammation, Malnutrition, Celiac Disease, Anemia, Chronic disease	Altered Intercellular Communication	Although anemia is still a common presentation of celiac disease, nutritional deficiencies alone do not explain this phenomenon in all cases; inflammation appears to contribute as evidenced by the presence of anemia of chronic disease in some individuals.	17636474
Inflammation	Altered Intercellular Communication	In patients with chronic inflammation, amyloidomas must be considered in the differential diagnosis of mass lesions so the appropriate work-up can be undertaken to minimize this potential pitfall.	17636494
Inflammation, Meckel Diverticulum, Congenital Abnormality, Small intestine carcinoma, Crohn Disease, Ulceration of intestine	Altered Intercellular Communication	These lesions mainly consisted of small intestinal ulcer (including Crohn's disease), chronic inflammation, Meckel's diverticulum, interstizialoma, vascular deformity and carcinoma of small intestine.	17637306
Bronchitis	Altered Intercellular Communication	Implication of dipeptidylpeptidase IV activity in human bronchial inflammation and in bronchoconstriction evaluated in anesthetized rabbits.	17637510
Bronchitis	Altered Intercellular Communication	To investigate and correlate the role of DPPIV activity with regard to bronchial inflammation.	17637510
Bronchitis	Altered Intercellular Communication	DPPIV/CD26 activity/concentration was investigated in the bronchial tissue of human subjects suffering from chronic bronchial inflammation.	17637510
Airway structure	Altered Intercellular Communication	As previously reported for the nasal mucosa, DPPIV/CD26 activity was inversely correlated with the degree of airway inflammation.	17637510
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	An immunohistochemical analysis of EPOR was performed on 30 PCa, 50 BPH with/without inflammation lesions and 30 normal prostatic tissue samples.	17637760
Inflammation, Ulceration, CTCAE, Granulation finding	Altered Intercellular Communication	Histologic examination revealed fibrous stromal cores with squamous epithelial covering and various degrees of ulceration and accompanying inflammation and granulation tissue.	17638430
Lupus Erythematosus, Discoid	Altered Intercellular Communication	Discoid lupus erythematosus is a chronic inflammatory condition in which the pathogenesis and the role of cell-mediated immunity remains unclear.	17638731
Eosinophilic disorder	Altered Intercellular Communication	These data support a link between eosinophilia and the presence of paranasal sinus mucosal inflammation.	17638784
Steatohepatitis, Infection caused by Helicobacter pylori, Biliary calculi	Altered Intercellular Communication	Liver steatosis did not statistically improve, nor did inflammatory conditions of the upper digestive tube, despite reduction of H. pylori infections; gallbladder stones requiring intervention were common.	17639175
Inflammation, Musculoskeletal torsion, function, Neoplasms	Altered Intercellular Communication	Benign neoplasms rarely contained FFLs (4/102, 3.9%); those that did were commonly associated with complications such as torsion or inflammation.	17639405
Inflammation, Autoimmune Chronic Hepatitis	Altered Intercellular Communication	Portal and periportal inflammation, consistent with autoimmune hepatitis, was diagnosed histologically after performing laparoscopic liver biopsy.	17639966
Inflammation, Restenosis	Altered Intercellular Communication	Inflammation in the injured vessel wall plays an essential role in the mechanism of restenosis.	17640648
Acute Coronary Syndrome, Inflammation	Altered Intercellular Communication	Reduced clot permeability and susceptibility to lysis in patients with acute coronary syndrome: effects of inflammation and oxidative stress.	17640649
Inflammation, Hypomagnesemia	Altered Intercellular Communication	Magnesium depletion is independently associated with elevated hsCRP levels, suggesting that hypomagnesemia and low-grade inflammation are interactive risk factors.	17641003
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	These results indicate that short-term low-dosage pioglitazone may improve vascular function via increasing adiponectin expression and decreasing low-grade inflammation in type 2 diabetic patients.	17641441
Airway structure, ARCN1 gene	Altered Intercellular Communication	Exhaled breath condensate 8-isoprostane, clinical parameters, radiological indices and airway inflammation in COPD.	17641539
Airway structure, ARCN1 gene	Altered Intercellular Communication	To investigate the relationship between 8-isoprostane level in EBC and clinical parameters, radiological indices and airway inflammation in COPD patients.	17641539
Inflammation, Obesity	Altered Intercellular Communication	This study explored the genetic variation in the SEPS1 locus for an association with CVD as well as with quantitative phenotypes related to obesity and inflammation.	17641917
Communicable Diseases, Inflammation	Altered Intercellular Communication	In the course of the first few postoperative days, inflammation is aggravated due to infection of the wound in the throat and the latter mechanism alone may be insufficient.	17642138
Airway structure, UGCG gene	Altered Intercellular Communication	COPD-associated airway inflammation may be affected by multiple factors, including cigarette smoking and glucocorticosteroid (GCS) treatment.	17643055
Airway structure, UGCG gene, ARCN1 gene	Altered Intercellular Communication	GCS treatment did not appear to affect these non-invasive markers of airway inflammation in COPD.	17643055
Airway structure, Asthma, Bronchitis	Altered Intercellular Communication	Bronchial asthma is a chronic airway disorder characterized by bronchial inflammation.	17643058
Inflammation	Altered Intercellular Communication	Isolated granulomatous inflammation of the appendix is extremely rare, and its etiology is still unknown.	17643216
Inflammation	Altered Intercellular Communication	These preliminary and novel data suggest that in addition to low albumin, a previously described marker of outcome, systemic inflammation is likely to be important in the pathogenesis of important PC.	17643996
Shock, Inflammation	Altered Intercellular Communication	Heat shock proteins and chemokine/cytokine secretion profile in ageing and inflammation.	17644159
Inflammation, HMOX1 gene	Altered Intercellular Communication	This difference disappeared for patients with inflammation who had increased levels of Hsp32, Hsp70 and Hsp90 compared to normal subjects.	17644159
Inflammation, Carotid Intima-Media Thickness	Altered Intercellular Communication	Both cyclooxygenase- and cytokine-mediated inflammation are associated with carotid intima-media thickness.	17644349
Inflammation	Altered Intercellular Communication	This study suggests both COX- and cytokine-mediated inflammation to be independently associated with increased CCA-IMT, implying that there might be more than one mode of inflammation involved in atherogenesis.	17644349
ARCN1 gene, Inflammation, exacerbation acute	Altered Intercellular Communication	Longitudinal follow-up of systemic inflammation after acute exacerbations of COPD.	17644367
Inflammation	Altered Intercellular Communication	Systemic inflammation is now considered as an important component in the disease process.	17644367
ARCN1 gene, Inflammation, exacerbation acute	Altered Intercellular Communication	This study clearly demonstrates upregulation of systemic inflammation in acute exacerbations of COPD.	17644367
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	Attenuation of systemic inflammation may offer new perspectives in the management of COPD patients to reduce the burden of exacerbations.	17644367
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	An abnormal CD4+ T cell subset related to inflammation exposure (inflammation-related cells, IRC) has been identified in rheumatoid arthritis (RA).	17644540
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Patients with inflammatory and non-inflammatory diseases were used to examine the relationship between inflammation and this T cell subset in vivo.	17644540
Refractory anemias, Inflammation	Altered Intercellular Communication	These results suggest a model in which, despite the lack of systemic inflammation, IRC persist in remission, indicating that IRC are an acquired feature of RA.	17644540
Inflammation	Altered Intercellular Communication	IRC persistence in remission confirms their important role in chronic inflammation as circulating precursors of pathogenic cells.	17644540
Malignant neoplasm of cardioesophageal junction of stomach	Altered Intercellular Communication	Comparison of an inflammation-based prognostic score (GPS) with performance status (ECOG-ps) in patients receiving palliative chemotherapy for gastroesophageal cancer.	17645468
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	A high level of total homocysteine (tHcy) is a risk marker for cardiovascular disease (CVD), and is related to inflammation.	17645592
Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Chronic disease, Liver Cirrhosis	Altered Intercellular Communication	31P-MRS using DRESS was used to compare absolute liver metabolite concentrations (PME, Pi, PDE, gammaATP, alphaATP, betaATP) in two distinct groups of patients with chronic diffuse liver disorders, one group with steatosis (NAFLD) and none to moderate inflammation (n=13), and one group with severe fibrosis or cirrhosis (n=16).	17646074
ARCN1 gene, Inflammation	Altered Intercellular Communication	These results suggest that MMP-2 may be a key mediator of the mechanisms leading to lung tissue remodeling and inflammation in patients with severe COPD.	17646237
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	If they are associated with inflammation or fibrosis of retroperitoneal periureteral fat nephrectomy may become necessary.	17646789
Increased insulin level, Inflammation	Altered Intercellular Communication	Apelin has recently been shown to be secreted by the adipose tissue in association with hyperinsulinemia and inflammation.	17647139
Inflammation	Altered Intercellular Communication	By contrast, the histology of the imported case of HEV infection showed less intense portal and acinar inflammation, no cholangiolitis and no geographical distribution of the portal inflammatory infiltrate.	17650215
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Furthermore, a nonstatistically significant difference in fibrosis and inflammation between the two patient groups was found.	17650288
Exacerbation of asthma, allergic inflammation	Altered Intercellular Communication	Serum hs-CRP levels may be related to the state of asthma exacerbation and allergic inflammation.	17650829
Airway structure, Asthma	Altered Intercellular Communication	Transforming growth factor (TGF)-beta plays an important role in the regulation of airway inflammation and remodelling in asthma.	17651146
Asthmatic Airway Remodeling, Asthma	Altered Intercellular Communication	These data suggest that clinical markers remain the most sensitive measures of early deterioration in asthma during back-titration of ICS, occurring at a time when AHR and conventional indices of asthmatic airway inflammation appear unchanged.	17651149
Inflammation	Altered Intercellular Communication	Angiotensin-converting enzyme (ACE) plays an important role in the physiological control of blood pressure and inflammation.	17651310
Inflammation, Fatty degeneration, Siderosis	Altered Intercellular Communication	The histological examination, in particular of the gallbladder bed of the liver, disclosed siderosis, inflammation, and fatty degeneration.	17651567
Tumor necrosis, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	A profound tumour necrosis factor alpha down-regulation appears to be strictly associated with a dramatic regression of the inflammation in patients with moderate-to-severe ulcerative colitis treated with infliximab.	17652038
Pheochromocytoma, Adrenal incidentaloma	Altered Intercellular Communication	Hormonal workup of the adrenal incidentaloma revealed elevated urinary catecholamine and total metanephrines findings strongly suggestive of a pheochromocytoma.	17652801
Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation and the metabolic syndrome (MetS) are important risk factors in cardiovascular disease.	17652887
Inflammation	Altered Intercellular Communication	Associations of low-grade inflammation with physical activity, fitness and fatness in prepubertal children; the European Youth Heart Study.	17653064
Inflammation	Altered Intercellular Communication	To examine the associations of low-grade inflammation with objectively measured physical activity, cardiovascular fitness (CVF) and fatness in prepubertal children.	17653064
Inflammation	Altered Intercellular Communication	Low-grade inflammation was not associated with physical activity, but physical activity was associated with CVF.	17653064
Inflammation	Altered Intercellular Communication	The findings suggest that the potential beneficial effects of physical activity on low-grade inflammation may be explained by its association with CVF.	17653064
physiopathological	Altered Intercellular Communication	Inflammatory processes and primary hormonal dysfunction were excluded.	17653274
Inflammation, Gastric metaplasia, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Only mild chronic inflammation, but not gastric metaplasia, was found in the control group, none with H. pylori infection in the duodenal bulb.	17653441
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is a disease of the colon and rectum characterized by a nonspecific chronic inflammation mediated by the concerted response of cellular and humoral events.	17653443
Inflammation, Obesity, Abdominal, Diabetes Mellitus	Altered Intercellular Communication	GADA-positive and GADA-negative non-diabetic individuals had similar risk profiles for diabetes, with central obesity and elevated inflammation markers, aside from glucose, being the main predictors.	17653446
Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Metabolic and hormonal changes associated with the reproductive history of women may contribute to the development of cardiovascular disease (CVD).	17653887
Inflammation, Calcification of coronary artery	Altered Intercellular Communication	Thirty-month follow-up of coronary artery calcification in hemodialysis patients: different roles for inflammation and abnormal calcium-phosphorous metabolism?	17654327
Inflammation	Altered Intercellular Communication	The roles of inflammation and abnormal calcium-phosphorous metabolism in CAC differ.	17654327
Inflammation, SLC25A20 gene	Altered Intercellular Communication	Inflammation is the major factor that contributes in CAC initiation.	17654327
Inflammation	Altered Intercellular Communication	Cicatrization and VA may still progress and worsen despite adequate control of inflammation.	17655931
Polyarteritis Nodosa, Inflammation	Altered Intercellular Communication	Isolated polyarteritis nodosa in the testes presents similar histologic characteristics as those of systemic inflammation, although infarcted areas in the testis are more common in generalized polyarteritis nodosa.	17656237
Inflammation	Altered Intercellular Communication	The complication is caused by chronic and recurrent inflammation due to HS with subsequent blockade or destruction of local lymph drainage routes.	17657186
Inflammation, Bacterial Infections, Diabetic Angiopathies, Vasospasm	Altered Intercellular Communication	In bacterial shunt infection, CNS inflammation is a frequently observed complication that may cause vascular complications including vasospasms.	17657654
Hip Joint, Inflammation, Joint structure of shoulder region, Synovitis	Altered Intercellular Communication	Patients with previously undiagnosed synovitis in at least one peripheral joint or signs of inflammation in sacroiliac, glenohumeral or hip joints were enrolled on their first hospital visit in 2000 and followed-up for up to 24 months in Kuopio.	17657673
Inflammation, Dysplasia, Primary malignant neoplasm, Metaplasia, Hyperplasia	Altered Intercellular Communication	The pathological diagnosis was normal in 123, inflammation, hyperplasia or metaplasia in 120, mild or moderate dysplasia in 8, severe dysplasia in 14 and cancer in 23.	17659811
Metaplastic, Inflammation, Cystitis	Altered Intercellular Communication	Cystitis glandularis (CG) is a well-known metaplastic lesion occurring in the presence of chronic inflammation, but there are a few data about mucin expression in its two subtypes (typical and intestinal).	17659847
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Relation of plasma lipoprotein levels with low-grade inflammation in white men without clinical evidence of myocardial ischemia.	17659927
Inflammation, Compression	Altered Intercellular Communication	Bone wax use should be limited in spinal surgery because of the potential for compression and chronic inflammation.	17660169
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	The role of the selenoprotein S (SELS) gene -105G>A promoter polymorphism in inflammatory bowel disease and regulation of SELS gene expression in intestinal inflammation.	17661913
Inflammation, Chest Pain, Ventricular Dysfunction, Left	Altered Intercellular Communication	Early risk stratification of patients with chest pain may be improved by combining cardiac Troponin I (cTnI) results and ECG findings with markers of left-ventricular dysfunction, inflammation or renal function.	17662484
Retinal Vein Occlusion, Hyperviscosity syndrome	Altered Intercellular Communication	However, when a patient less than 50 years of age has bilateral and simultaneous central retinal vein occlusions, a hyperviscosity syndrome or inflammatory condition is also suspected.	17662929
Vasculitis	Altered Intercellular Communication	The primary pathology of this case was, thus, considered to be meningeal and vascular inflammation consistent with the stage III meningovascular neurosyphilis.	17663152
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	To examine relationships between markers of systemic inflammation and functional status in patients with chronic obstructive pulmonary disease (COPD).	17665081
Inflammation	Altered Intercellular Communication	Inflammation increased with MRC grade and was significantly different across grades; CRP (p=0.002) and IL6 (p=0.04).	17665081
ARCN1 gene, Inflammation	Altered Intercellular Communication	Measures of systemic inflammation, and in particular CRP, may prove to be useful markers in the assessment of COPD severity in primary care.	17665081
methyldopa, Inflammation	Altered Intercellular Communication	Biochemical and genetic studies have suggested that inflammation and complement activation may play roles in AMD.	17666404
Inflammation, Hypertriglyceridemia, Congenital Abnormality	Altered Intercellular Communication	Postprandial hypertriglyceridemia is associated with a series of atherogenic abnormalities, including a prothrombotic state and inflammation.	17666915
vascular inflammations, Hypertriglyceridemia, Hypertension, CTCAE	Altered Intercellular Communication	In conclusion, postprandial hypertriglyceridemia induces postprandial fibrinolytic dysfunction and vascular inflammation in patients with essential hypertension after a high-fat meal.	17666915
Acute Coronary Syndrome, Inflammation	Altered Intercellular Communication	In-hospital outcome of patients with acute coronary syndrome: relationship with inflammation and remodeling markers.	17667031
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	In conclusion, a different biochemical pattern characterizes ACS patients: those with NR-UA show only an increase of remodeling markers, whereas ACS patients with NSTEMI have an increase of both remodeling and inflammation markers.	17667031
Inflammation, FBN2 wt Allele, Psoriasis, Stasis dermatitis	Altered Intercellular Communication	These cases demonstrate CCA in settings that reflect chronic inflammation, primarily scars and stasis dermatitis, and with an immunophenotype that parallels psoriasis.	17667172
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	One might speculate that bacterial stimuli accelerate the process of inflammation and fibrosis in patients who tend to develop capsular fibrosis.	17667403
Inflammation, Fibrosis Assessment, Fatty degeneration, Necrosis	Altered Intercellular Communication	In a retrospective analysis, histological findings of 79 donor liver grafts were assessed according to criteria inflammation, fibrosis, fatty degeneration, and necrosis.	17667804
Fibrosis Assessment, Portal inflammation	Altered Intercellular Communication	However, stage 3 and 4 fibrosis 1 year after liver transplantation was significantly increased in the group of patients receiving a graft from a donor with portal inflammation (P<0.05).	17667804
Intrahepatic Route of Drug Administration	Altered Intercellular Communication	Additionally, the occurrence of intrahepatic inflammation was significantly increased in older donors (P<0.05) and donors with prolonged intensive care hospitalization (P<0.05).	17667804
Inflammation, Spondylarthropathies	Altered Intercellular Communication	Conventional disease-modifying antirheumatic drugs fail to inhibit axial inflammation in spondylarthropathy, in contrast to TNFalpha-blocking agents.	17668597
Neoplasms	Altered Intercellular Communication	There's a hypothesis, that it plays a significant role in middle ear chronic inflammations and neoplasm's.	17668798
Coinfection, Carcinogenesis, Virus Diseases, Neoplasms	Altered Intercellular Communication	It is concluded, that differences in percentages of HPV presence in chronic inflammations (70%) and ear neoplasm's may be explained by viral co-infection during bacterial c. o. m. Viral infection probably evolves carcinogenesis, which leads to a neoplastic growth.	17668798
Inflammation, Communicable Diseases, Herpes Simplex Infections, herpesvirus 3, human, Cytomegalovirus	Altered Intercellular Communication	Despite the posterior location of inflammation, aqueous analyses with PCR and GWC for HSV, VZV, CMV, and T. gondii revealed an infectious cause in 29% of patients with PU.	17669497
Celiac Disease, Inflammation, Villous atrophy	Altered Intercellular Communication	Upper endoscopy showed villous atrophy, and small bowel biopsy confirmed the presence of villous blunting and chronic inflammation, consistent with celiac sprue.	17669718
Caustic Injury, Inflammation	Altered Intercellular Communication	Nasogastric intubation is not a simple procedure as is the general concept and it should not be done in cases of caustic injury to the esophagus because of increased risk of complications in the face of preexisting inflammation.	17669920
Inflammation, Candidiasis	Altered Intercellular Communication	In addition, the inflammation caused by candidiasis and found in the early examination was improved.	17671416
Malnutrition, Coronary Artery Disease, Hepatitis C	Altered Intercellular Communication	Malnutrition inflammation score is associated with coronary artery disease in hepatitis C virus-infected hemodialysis patients.	17671439
HD Term Type, Malnutrition, Coronary Artery Disease	Altered Intercellular Communication	We investigated whether malnutrition inflammation score (MIS) is associated with the presence of coronary artery disease (CAD) in anti-HCV-positive hemodialysis (HD) patients.	17671439
Granulomatous inflammation, Sarcoidosis, Chronic inflammatory disorder	Altered Intercellular Communication	Sarcoidosis is a chronic inflammatory disease characterised by granulomatous inflammation in various organs.	17671745
Inflammation, Coronary heart disease	Altered Intercellular Communication	Intensive reduction of LDL-C with atorvastatin improves endothelium-dependent vasodilation and reduces markers of inflammation in patients with coronary disease.	17673219
Cerebrovascular Disorders, Inflammation, Coronary heart disease	Altered Intercellular Communication	Inflammation has been known as a risk factor for coronary heart disease, whereas inflammation as a risk for cerebrovascular disease is less well established.	17673235
Inflammation	Altered Intercellular Communication	The impact of inflammation in the pathogenesis of small vessel disease-related brain lesions seems to be weak among the Japanese elderly.	17673235
Pulmonary arterial hypertension, Inflammation, Polycyclic Hydrocarbons, Aromatic	Altered Intercellular Communication	Pulmonary arterial hypertension (PAH) is a fatal disease associated with inflammation and pathological remodeling of the pulmonary artery (PA).	17673672
Airway structure	Altered Intercellular Communication	These findings suggest that the HIF-1alpha pathway is activated in response to subepithelial remodeling and contributes to progressive premalignant epithelial lesions in the airways of tobacco smokers with chronic airway inflammation.	17674038
Inflammation	Altered Intercellular Communication	Both TrkB and BDNF were expressed in NPC as well as in chronic inflammation.	17674765
Inflammation	Altered Intercellular Communication	The active expression rate of TrkB in NPC was 82.5% (47/57) and BDNF was 52.6% (30/57), both of which were higher than those in chronic inflammation (P < 0.05).	17674765
Gastrointestinal inflammation	Altered Intercellular Communication	We performed the first study analysing faecal S100A12 in adults with signs of intestinal inflammation.	17675327
Gastrointestinal inflammation	Altered Intercellular Communication	Faecal S100A12 correlated better with intestinal inflammation than faecal calprotectin or other biomarkers.	17675327
Gastrointestinal inflammation	Altered Intercellular Communication	As a marker for neutrophil activation, faecal S100A12 may significantly improve our arsenal of non-invasive biomarkers of intestinal inflammation.	17675327
Hepatic inflammation, Hepatocarcinogenesis	Altered Intercellular Communication	Therapeutic strategy for hepatic inflammation seems to be important for long-term prevention of hepatocarcinogenesis.	17675825
Inflammatory abnormality of the eye, Skin lesion	Altered Intercellular Communication	Disease manifestations consist of recurrent oral and genital ulceration, skin lesions, and relapsing ocular inflammation.	17676219
Encephalitis, Inflammation	Altered Intercellular Communication	Acute encephalitis is an inflammation of brain tissue that can result from activity in the central nervous system (CNS) of a number of viruses.	17676531
Inflammation	Altered Intercellular Communication	In the central nervous system, increased expression of astroglial-derived S100B protein has been associated with the onset and maintaining of inflammation.	17678654
Gastrointestinal inflammation	Altered Intercellular Communication	The role of enteric glial-derived S100B protein in gastrointestinal inflammation has never been investigated in humans.	17678654
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Polymorphism in genes encoding T-cell regulatory proteins and cytokines may influence inflammation and cancer development via regulation of antitumor immune response.	17678726
Inflammation, Urolithiasis	Altered Intercellular Communication	Unspecific intestine inflammations have an influence on the occurrence of crystallization risk states, as well as a fully symptomatic urolithiasis.	17679383
Inflammation, Bulla	Altered Intercellular Communication	Occasionally, even frank bullae appear secondary to severe inflammation.	17681052
Hepatic inflammation, Fatty degeneration	Altered Intercellular Communication	Steatosis, hepatocyte injury, and hepatic inflammation were assessed by histology, immunohistochemistry, and biochemical analysis.	17681180
Inflammation, Liver damage, Fatty degeneration	Altered Intercellular Communication	After choline-methionine-deficient diet, Tph1(-/-) mice displayed an equal degree of steatosis, yet reduced hepatocellular injury and less severe inflammation.	17681180
Inflammation, Metabolic Syndrome X, Coronary heart disease	Altered Intercellular Communication	Inflammation, the metabolic syndrome, and risk of coronary heart disease in women and men.	17681508
Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	This study examined whether inflammation adds to the prediction of coronary heart disease (CHD) beyond metabolic syndrome (MetS), and whether these associations differ between sexes.	17681508
Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	The prevalence of inflammation in carotid atherosclerosis: analysis with fluorodeoxyglucose-positron emission tomography.	17681956
Plaque, Atherosclerotic	Altered Intercellular Communication	There is increasing evidence that (18)F-fluorodeoxyglucose (FDG)-positron emission tomography (PET) imaging can be useful for non-invasive measurement of atherosclerotic plaque inflammation in humans.	17681956
Inflammation, Atherosclerosis	Altered Intercellular Communication	However, it is unknown how often atherosclerosis has inflammation in humans.	17681956
Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	Thus, we examined the prevalence of inflammation in documented carotid atherosclerosis using FDG-PET imaging.	17681956
Inflammation, Atherosclerosis	Altered Intercellular Communication	The inflammation of carotid atherosclerosis was quantified by measuring the standardized uptake value (SUV) of FDG of the carotid artery.	17681956
Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	FDG-PET imaging revealed inflammation in 12 of 41 (29%) patients having carotid atherosclerosis, whereas in 6 of 59 (10%) patients not having carotid atherosclerosis (P < 0.01).	17681956
Inflammation, Atherosclerosis	Altered Intercellular Communication	In patients with documented atherosclerosis by CA-US, body mass index, waist circumference, and the number of localized plaques were greater in a subset with inflammation than in a subset without.	17681956
Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	Inflammation was visualized by FDG-PET imaging in approximately 30% of patients with documented carotid atherosclerosis.	17681956
Inflammation, Pneumonia, Communicable Diseases, Postoperative infection, Cellulitis, Urinary tract infection, abscess leg	Altered Intercellular Communication	The five most frequent diagnoses related to infection were "pneumonia, organism unspecified," "urinary tract infection, site not specified," "infection and inflammation, internal prosthetic device," "cellulitis and abscess of leg," and "postoperative infection."	17682240
Inflammation, Pneumonia	Altered Intercellular Communication	We analyzed the relationships between the duration of hospitalization and factors such as age, sex, severity of pneumonia, number of lobes with inflammation and the duration of tracheal intubation.	17682462
Inflammation, Periodontitis	Altered Intercellular Communication	After systematically periodontic treatment and controlling the inflammation, 12 cases with severe chronic periodontitis were extracted the residual teeth and received immediate implant placement.	17683673
Borrelia burgdorferi	Altered Intercellular Communication	It may be explained by the persistence of inflammatory conditions, perhaps related to surviving of a fraction of Borrelia burgdorferi spirochetes within CNS tissue.	17684925
Inflammation	Altered Intercellular Communication	Comparing the nonretrocaecal to the retrocaecal position by chi square, the non-retrocaecal position was more prone to inflammation (p<0.001).	17685212
Inflammation, Abscess, Hypopyon	Altered Intercellular Communication	Slit-lamp examination revealed intense anterior chamber inflammation with hypopyon and B-scan ophthalmic ultrasound showed a choroidal mass consistent with choroidal abscess.	17687520
Chronic liver disease, Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	Up-regulated eotaxin plasma levels in chronic liver disease patients indicate hepatic inflammation, advanced fibrosis and adverse clinical course.	17688666
Degenerative polyarthritis	Altered Intercellular Communication	This study demonstrates pro-inflammatory condition of OA pathology and supports the idea that vascularized subchondral region may increase the synthesis of cytokines and MMPs leading to degradation of adjacent cartilage.	17689092
Inflammation	Altered Intercellular Communication	Subsequent pathologic examination of the valve demonstrated infiltrating fibroconnective tissue and chronic inflammation.	17689922
Inflammation, Mirizzi Syndrome	Altered Intercellular Communication	A possible explanation is considered that the pathogenesis of Mirizzi syndrome is resulted from chronic inflammation due to adenomyomatosis.	17690046
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Raised interleukin-10 is an indicator of poor outcome and enhanced systemic inflammation in patients with acute coronary syndrome.	17690160
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	In contrast with some previous reports, we conclude that IL-10 reflects a proinflammatory state in patients with ACS and we therefore suggest that IL-10 is as effective a biomarker for the risk prediction of future cardiovascular events as other markers of systemic inflammation.	17690160
Inflammatory disease of mucous membrane, Duodenal Diseases	Altered Intercellular Communication	Higher MUC1 IgG antibody levels were associated with a higher degree of gastric corpus mucosa inflammation in patients with chronic gastroduodenal diseases (p < 0.0025).	17691020
Gastritis	Altered Intercellular Communication	This increase is associated with a higher IgG immune response to H. pylori and with a higher degree of gastric mucosa inflammation.	17691020
Inflammation, Hepatitis	Altered Intercellular Communication	Liver biopsies demonstrated active hepatitis, portal inflammation rich with eosinophils, ductular reaction and parenchymal inflammation with peri-central accentuation.	17692424
Inflammation, Pain Distress Question	Altered Intercellular Communication	Patients in the valdecoxib and naproxen groups had significantly improved efficacy compared with placebo in most of the other secondary assessments of inflammation, pain, and function.	17692722
Inflammation, Hemorrhagic cystitis, Edema	Altered Intercellular Communication	Cystoscopy findings revealed generalized inflammation and edema of the mucosa of the bladder, confirming the diagnosis of hemorrhagic cystitis.	17692730
Abnormal inflammatory response, Heart failure, Endothelial dysfunction	Altered Intercellular Communication	Heart failure (HF) is associated with coagulation activation, abnormal inflammation and endothelial dysfunction.	17692904
Refractory anemias, Inflammation, Synovitis	Altered Intercellular Communication	The ultrasonographic measurements of synovitis in RA patients provide valuable information on synovial inflammation.	17694257
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Inflammation appears to play a key role in the development of colorectal cancer (CRC).	17694420
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	In this study we examine factors involved in the regulation of inflammation and risk of CRC.	17694420
Colorectal Carcinoma	Altered Intercellular Communication	This study provides further support for inflammation-related factors in the etiology of CRC.	17694420
Inflammation, Pseudoaneurysm	Altered Intercellular Communication	Because of severe inflammation of his left upper extremity, the pseudoaneurysm was dealt with resection, ligation of the brachial artery above and below the defect and leaving the incision to heal by secondary intention.	17695041
Communicable Diseases, Inflammation	Altered Intercellular Communication	The biopsy of lesions on larynx, tonsil and epiglottis revealed "necrotising granulomatous inflammation" and histopathology supported TB infection.	17695696
Intestinal metaplasia, Inflammation, Gland, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Biopsy specimens from consecutive patients were examined and graded according to the Updated Sydney System for H pylori infection, chronic inflammation, neutrophil activity, glandular atrophy and intestinal metaplasia.	17696233
Intestinal metaplasia, Inflammation, Gland	Altered Intercellular Communication	The rate of the graded variables, in the antrum and corpus respectively, were as follows: H pylori infection (91%, 86%), chronic inflammation (98%, 93%), neutrophil activity (91%, 86%), glandular atrophy (57%, 15%) and intestinal metaplasia (11%, 2%).	17696233
Chronic inflammation	Altered Intercellular Communication	Significant association was found between the degree of H pylori colonisation with chronic inflammation, neutrophil activity and antral glandular atrophy.	17696233
Intestinal metaplasia, Inflammation, Gland	Altered Intercellular Communication	The majority of patients show a moderate to high degree of inflammation but a low degree of glandular atrophy and intestinal metaplasia.	17696233
Histiocytosis, Langerhans-Cell, Inflammation	Altered Intercellular Communication	We found that LCH lesions were a site of active inflammation, tissue remodeling, and neo-angiogenesis, and the majority of proliferating cells were endothelial cells, fibroblasts, and polyclonal T lymphocytes.	17696642
Nonspecific interstitial pneumonia, Sarcoidosis, Inflammation	Altered Intercellular Communication	In sarcoidosis and NSIP, prominent MMP-7 immunoreactivity was found in areas of inflammation.	17696954
Inflammation, Sensitization (observable entity)	Altered Intercellular Communication	Bronchial responsiveness in bakery workers: relation to airway symptoms, IgE sensitization, nasal indices of inflammation, flour dust exposure and smoking.	17697030
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Inflammation is assumed to play a major role in the progress of atherosclerotic disease.	17697159
Inflammation, Failure (biologic function)	Altered Intercellular Communication	The data indicate that a dysfunctional HPA axis response involves a failure to contain inflammatory activity in CAD patients, thus providing a possible link between stress and inflammation in disease.	17697159
Inflammation, Thrombosis	Altered Intercellular Communication	prothrombotic disorder or abdominal inflammation) were present in 87%.	17697371
Pain Distress Question, Inflammation, extrapyramidal tract, Edema	Altered Intercellular Communication	Extrapyramidal reactions and injection-site AEs, including pain, edema, wheals, and inflammation occurring up to 24 hours after surgery were recorded by a blinded investigator.	17697904
Acute myocardial infarction, Heart, Myocarditis	Altered Intercellular Communication	Sudden coronary death, fatal acute myocardial infarction and widespread coronary and myocardial inflammation.	17698556
Myocarditis	Altered Intercellular Communication	Groups 5 and 6 had no evidence of myocardial or coronary inflammation (p<0.001 vs groups 1, 2 and 3).	17698556
Sepsis, Inflammation, Communicable Diseases	Altered Intercellular Communication	Although severe sepsis is often attributed to uncontrolled and unbalanced inflammation, evidence from humans with infection syndromes across the breadth of disease is lacking.	17698689
Inflammation	Altered Intercellular Communication	We suggest a relationship between proximodistal phenotype, inflammation, and severity.	17698709
Inflammation, Septicemia	Altered Intercellular Communication	Septicemia, a common complication in chronic dialysis patients, may be an important factor in erythropoietin (EPO) hyporesponsiveness, because it is a form of inflammation.	17699252
Interstitial inflammation, Dysplasia of anus, Nephritis, Interstitial, Tubulitis Assessment, Kidney Failure, Acute	Altered Intercellular Communication	Acute interstitial nephritis (AIN) is a clinicopathologic entity that is characterized by acute renal failure and renal biopsy findings of interstitial inflammation and tubulitis.	17699278
Hypotension, CTCAE, Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	IL-6 data and the absence of correlation with measures of hypotension (e.g., mean arterial pressure, dosage of vasopressors) support the notion that inflammation is a significant component of AKI in SS.	17699383
Inflammation	Altered Intercellular Communication	A more marked inflammatory response in renal patients is suggested by more frequent presence and greater intensity of markers of inflammation.	17699396
Inflammation	Altered Intercellular Communication	A role for this receptor in inflammation and cell proliferation has recently been suggested in nonrenal tissues.	17699557
Communicable Diseases, Inflammation, Bovine Viral Diarrhea Viruses	Altered Intercellular Communication	Studies of astrovirus-infected humans and turkeys have demonstrated few histological changes and little inflammation during infection, suggesting that intestinal damage or an overzealous immune response is not the primary mediator of astrovirus diarrhea.	17699569
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	JCV PVAN was less common (21.4%) and was characterized by sparse cytopathic changes but significant inflammation and fibrosis.	17700156
Inflammation	Altered Intercellular Communication	Cholecystectomy is made hazardous by distortion of the anatomy of Calot's triangle by acute or chronic inflammation.	17701938
Inflammation	Altered Intercellular Communication	Pathologically, among children there are abundant of adenoidal lymph tissue, while in adults the lymph tissue getting less as age grows but with evident inflammation reaction.	17702419
Hyperparathyroidism	Altered Intercellular Communication	The most common potential causes of hyporesponse were iron deficiency (being reported in 39% of hyporesponse events), medication (immunosuppressive agents, ACE inhibitors), secondary hyperparathyroidism and inflammation/malnutrition.	17702511
Inflammation, Necrosis, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Agreement for steatosis was 93% (kappa = 0.91), inflammation 74% (kappa = 0.58), ballooning necrosis 84% (kappa = 0.73), fibrosis 98% (kappa = 0.96), and for the NAFLD activity score > or =5 was 93% (kappa = 0.83).	17702661
Inflammation, Hyperparathyroidism, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	Higher body mass index is associated with secondary hyperparathyroidism in patients who have chronic kidney disease and are not yet on dialysis, especially in patients with evidence of malnutrition and inflammation.	17702720
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Plasma protein pentraxin 3 concentrations were analyzed in relation to GFR, inflammation, cardiovascular disease, and protein-energy wasting in 71 patients with stages 3 to 4 chronic kidney disease, 276 patients with stage 5 chronic kidney disease, and 61 control subjects.	17702732
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Patients with protein-energy wasting, inflammation, and cardiovascular disease had higher concentrations of protein pentraxin 3 than their counterparts.	17702732
Inflammation, AHSG protein, human, Coronary Arteriosclerosis	Altered Intercellular Communication	Fetuin-A inhibits inflammation and has a protective effect against myocardial ischemia.	17702860
Inflammation, Wheezing	Altered Intercellular Communication	Early detection of airway wall remodeling and eosinophilic inflammation in preschool wheezers.	17702968
Airway structure, Wheezing, Thickened	Altered Intercellular Communication	We hypothesized that eosinophilic airway inflammation and epithelial reticular basement membrane (RBM) thickening, absent in wheezy infants, would be present in preschool children with severe, recurrent wheeze.	17702968
Inflammation, Wheezing	Altered Intercellular Communication	To compare RBM thickness and inflammation in endobronchial biopsies (EBs) from wheezy preschool children and age-matched control subjects.	17702968
Inflammation	Altered Intercellular Communication	Eosinophilic inflammation was significantly greater in CWs compared with control subjects (P < 0.05).	17702968
Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis is characterized by relapsing mucosal inflammation where the lesions include tissue-damaging granulocytes.	17703315
Inflammation	Altered Intercellular Communication	Chemokines are a large family of peptides that play key roles in the regulation of inflammation.	17703315
Inflammation	Altered Intercellular Communication	In clinical nonresponders, characterized by sustained inflammation, the levels of GRO-alpha and MIG remained elevated.	17703315
Adenocarcinoma, Inflammation, Michigan (geographic location)	Altered Intercellular Communication	The spectra were then separated in groups (N, normal; LI, light inflammation; MI, moderated inflammation; CA, adenocarcinoma), based on the histopathology.	17703349
Inflammation, Hemorrhage, Biliary calculi, Gallbladder Carcinoma, Choledocholithiasis, Injury of bile duct	Altered Intercellular Communication	The main reason for conversion was the unclear anatomy owing to previous inflammation, followed by bleeding and choledocholithiasis suspicion, gallbladder carcinoma, bile duct injury, or spilled gallstones.	17705718
Cholecystitis, Obesity	Altered Intercellular Communication	It was significantly increased in males (11.6%) and the elderly (12.4 %), gallbladder inflammation (29%), and morbid obesity (50%).	17705718
Inflammation	Altered Intercellular Communication	The risk for the conversion of laparoscopic cholecystectomy increases significantly in males, the elderly, obese patients, and when inflammation is present.	17705718
Inflammation	Altered Intercellular Communication	Histological examination of biopsy specimens mainly showed nonspecific chronic inflammation.	17706058
Inflammation, Rheumatoid Arthritis, Fatigue	Altered Intercellular Communication	Chronic stress and regulation of cellular markers of inflammation in rheumatoid arthritis: implications for fatigue.	17706915
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	This study examined whether chronic interpersonal stress is associated with cellular markers of inflammation and regulation of these responses by in vitro doses of glucocorticoids in rheumatoid arthritis (RA) patients.	17706915
Inflammation, Fatigue	Altered Intercellular Communication	The association between these markers of inflammation and fatigue was also tested.	17706915
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Predictors of inflammation in response to anthracycline-based chemotherapy for breast cancer.	17706918
Inflammation	Altered Intercellular Communication	These findings indicate that chemotherapy treatment can be associated with elevations in certain markers of inflammation, particularly markers of endothelial and platelet activation.	17706918
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Parameters of inflammation and fibrinogen were additionally measured in ulcerative colitis patients.	17708267
Inflammation	Altered Intercellular Communication	However, in subglottic cases it is unclear whether the chronic inflammation arises from a local or systemic process.	17708368
Inflammation, Primary malignant neoplasm, Meckel Diverticulum, Congenital Abnormality, Ulceration, CTCAE	Altered Intercellular Communication	Diseases of the small intestine include, among others, ulceration, chronic inflammation, Meckel's diverticula, vascular deformities, and cancer.	17709022
Inflammation, Meckel Diverticulum, Carcinoma, Congenital Abnormality, Ulcer, Crohn Disease	Altered Intercellular Communication	These lesions found were small-intestinal ulcers (including Crohn's disease), chronic inflammation, Meckel's diverticulae, vascular deformities, and carcinoma.	17709022
Inflammation	Altered Intercellular Communication	Excess adiposity is associated with greater systemic inflammation.	17709633
Inflammation	Altered Intercellular Communication	The present cross-sectional data support an association between both SAT and VAT with inflammation and oxidative stress.	17709633
Inflammation, Obesity	Altered Intercellular Communication	The data suggest that the contribution of visceral fat to inflammation may not be completely accounted for by clinical measures of obesity (body mass index and waist circumference).	17709633
Hashimoto Disease, Inflammation, Fever, CTCAE	Altered Intercellular Communication	Although we did not assume that the inflammation was related to Hashimoto's thyroiditis, total thyroidectomy was performed for cosmetic reasons; however, fever was resolved immediately after thyroidectomy.	17709903
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Against all expectations, biopsy revealed granulomatous inflammation with epitheloid giant cells and caeseating necrosis.	17710028
Xanthogranulomatous inflammation, Fibrosis Assessment, Calcinosis	Altered Intercellular Communication	So far, only a small number of cases of xanthogranulomatous inflammation occurring in female genital tract have been described, most frequently affecting the endometrium and histologically characterized by replacement of endometrium by xanthogranulomatous inflammation composed of abundant foamy histiocytes, siderophages, giant cells, fibrosis, calcification and accompanying polymorphonuclear leucocytes, plasma cells and lymphocytes of polyclonal origin.	17710239
Inflammation, Fatty Liver Disease	Altered Intercellular Communication	Furthermore, IL-8 was found to be higher in the NASH group than in the hepatosteatosis group, demonstrating the importance of inflammation in the pathogenesis of NASH.	17710676
Allergic asthma, Airway structure	Altered Intercellular Communication	Allergic asthma is an immunoglobulin E (IgE)-mediated disease characterized by frequent exacerbations following exposure to relevant allergens that leads to the development of chronic airway inflammation.	17711616
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The final pathology revealed chronic inflammation and there was no malignancy, and no bacteria or mycobacterium were seen.	17711963
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) is characterized by beta-amyloid plaques, tau pathology, cholinergic cell death and inflammation.	17712316
Inflammation, Obesity	Altered Intercellular Communication	Our data show a strong association between adipose tissue inflammation and ECS activation in obesity, and indicate that a pro-inflammatory state may directly activate the ECS.	17712725
Inflammation, Lung Diseases, Obstructive	Altered Intercellular Communication	The patient had evidence of irreversible obstructive lung disease and lung biopsy showed typical findings of chronic inflammation, submucosal thickening and obliteration of bronchioles.	17713324
Hereditary Diseases, Communicable Diseases, Inflammation, Neoplasms	Altered Intercellular Communication	The amyloidogenic disease was a chronic infection (40.8%), a chronic inflammation (38%), a tumor (9.9%), a hereditary disease (9.9%), or was undetermined in 1.4% of cases.	17714761
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Since chronic obstructive pulmonary disease (COPD) is characterised by inflammation and oxidative stress, low-dose CO could be of therapeutic use.	17715164
Inflammation, Depressed mood, Depression, CTCAE, Chronic disease	Altered Intercellular Communication	The association between inflammation and depression may depend on the presence of specific chronic diseases or be relevant in specific sub-groups of depressed patients only.	17716746
vascular inflammations	Altered Intercellular Communication	Vascular endothelial sampling and analysis of gene transcripts: a new quantitative approach to monitor vascular inflammation.	17717122
vascular inflammations, Cardiovascular Diseases	Altered Intercellular Communication	Limited access to endothelial tissue is a major constraint when investigating the cellular mechanisms of vascular inflammation in patients with cardiovascular and metabolic diseases.	17717122
vascular inflammations	Altered Intercellular Communication	Venous endothelial sampling coupled to real-time PCR analysis is a minimally invasive, safe, and reliable technique to monitor vascular inflammation in human subjects.	17717122
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	These findings suggest that resident cells in pulmonary fibrosis can sustain chronic inflammation by driving the accumulation of DCs with the potential to mature locally within ectopic lymphoid follicles.	17717200
Pain Distress Question, Inflammation	Altered Intercellular Communication	All patients had prolonged and severe pain before surgery and inflammation of the operative knee.	17717244
Inflammation, Ischemic stroke	Altered Intercellular Communication	Iron oxide particle-enhanced MRI suggests variability of brain inflammation at early stages after ischemic stroke.	17717318
Inflammation, Brain Injuries, Ischemic stroke	Altered Intercellular Communication	Inflammation contributes to brain damage caused by ischemic stroke.	17717318
Inflammation, Carcinoma, Transitional Cell	Altered Intercellular Communication	In addition, 10 voided urine samples from cases with grade 3 demonstration urothelial carcinoma (G3UC) and 30 voided urine samples from 25 patients with a histologic diagnosis of chronic inflammation of the bladder were evaluated for comparison.	17718119
Ischemic	Altered Intercellular Communication	Inflammation of the vessel wall following neutrophil adhesion to vascular endothelium may contribute to ischemic damage.	17718692
Peripheral Vascular Diseases, Inflammation, Atherosclerosis	Altered Intercellular Communication	C-reactive protein (CRP), a specific marker of inflammation, has been found to be related to CVD and subclinical atherosclerosis, including peripheral arterial disease (PAD).	17719297
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Recent studies have implicated systemic inflammation in the genesis and maintenance of atrial fibrillation (AF).	17719315
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	However, there is no information concerning the association between inflammation and AF in patients with AMI.	17719315
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	Inflammation may contribute to the development of AF in the setting of AMI.	17719315
Inflammation, Rheumatoid Arthritis, Aortic Stiffness	Altered Intercellular Communication	Ezetimibe and simvastatin reduce inflammation, disease activity, and aortic stiffness and improve endothelial function in rheumatoid arthritis.	17719471
Refractory anemias, Inflammation	Altered Intercellular Communication	Statins reduce inflammation and disease activity in RA patients, but whether this is due to pleiotropism or cholesterol lowering per se is unclear.	17719471
Rheumatoid Arthritis	Altered Intercellular Communication	Rheumatoid arthritis is a chronic inflammatory condition associated with increased cardiovascular risk.	17719471
Plaque, Atherosclerotic, Atherosclerosis	Altered Intercellular Communication	(18)Fluorodeoxyglucose positron emission tomography imaging of atherosclerotic plaque inflammation is highly reproducible: implications for atherosclerosis therapy trials.	17719477
Inflammation	Altered Intercellular Communication	By tracking changes in inflammation over time, PET could be used as a surrogate marker of antiatheroma drug efficacy.	17719477
Inflammation	Altered Intercellular Communication	On histology, transmural granulomatous inflammation composed of abundant eosinophils, lymphocytes, histiocytes and giant cells was seen.	17719761
Necrotizing granulomatous inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histopathologic evaluation of the surgical specimen revealed chronic nongranulomatous inflammation and fibrosis in the peripheral skirt, indicating that biointegration was maintained.	17721307
Inflammation, Autoimmune reaction	Altered Intercellular Communication	Use of IVTAin paraneoplastic autoimmune optic neuritis and vitreitis related to CRMP-5-IgG was followed by a marked decrease in inflammation and stabilization or improvement of vision.	17721501
ovarian neoplasm, Pelvic Inflammatory Disease	Altered Intercellular Communication	Talcum powder, chronic pelvic inflammation and NSAIDs in relation to risk of epithelial ovarian cancer.	17721999
Inflammation, ovarian neoplasm	Altered Intercellular Communication	Chronic inflammation has been proposed as the possible causal mechanism that explains the observed association between certain risk factors, such as the use of talcum powder (talc) in the pelvic region and epithelial ovarian cancer.	17721999
Oophoritis, ovarian neoplasm	Altered Intercellular Communication	To address this issue we evaluated the potential role of chronic local ovarian inflammation in the development of the major subtypes of epithelial ovarian cancer.	17721999
Oophoritis, Endometrioid tumor, ovarian neoplasm, Endometriosis, Human papilloma virus infection, Pelvic Inflammatory Disease	Altered Intercellular Communication	Other factors potentially associated with ovarian inflammation (pelvic inflammatory disease, human papilloma virus infection and mumps) were not associated with risk but, like others, we found an increased risk of endometrioid and clear cell ovarian cancer only among women with a history of endometriosis.	17721999
Inflammation, ovarian neoplasm	Altered Intercellular Communication	We conclude that on balance chronic inflammation does not play a major role in the development of ovarian cancer.	17721999
Inflammation	Altered Intercellular Communication	The frequency of granulomatous inflammation was highest in NV.	17722231
Inflammation, Tooth Loss, Metabolic Syndrome X	Altered Intercellular Communication	Tooth loss is related to the presence of metabolic syndrome and inflammation in elderly subjects: a prospective study of the vasculature in Uppsala seniors (PIVUS).	17722439
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	To investigate how the number of remaining teeth relates to the presence of metabolic syndrome (MetS) and markers of inflammation.	17722439
Inflammation, Tooth Loss, ETV3 wt Allele	Altered Intercellular Communication	In addition to established risk factors for tooth loss, the presence of MetS and inflammation were independent predictors of the number of teeth in an elderly population.	17722439
Inflammation, Infiltration, Ionizing radiation	Altered Intercellular Communication	The morphological features of FCT in the persons who had long lived in the radioactively polluted areas were marked lung destructive and fibrotic changes, a decrease in the detection rate ofgranulomatous inflammation, and a weak local lymphoid infiltration, which may indirectly suggest the low level of cellular immunity upon exposure to ionizing radiation.	17722592
Inflammation	Altered Intercellular Communication	The esophageal mucosa was covered with the papillomatously changed laminated squamous epithelium with chronic inflammation in the mucous stroma.	17722600
Motor Disorders, Pain Distress Question, Inflammation, Complex Regional Pain Syndromes	Altered Intercellular Communication	Algodystrophy syndrome is characterized by pain, vasomotor disorders and/or trophic skin changes, without laboratory signs of inflammation.	17722788
Inflammation, Carcinogenesis	Altered Intercellular Communication	In a recent study, prostatectomy specimens from which Propionibacterium acnes was cultured were more likely to have inflammation than culture-negative specimens or specimens positive for other bacteria, leading the authors to hypothesize that P. acnes-mediated inflammation may contribute to prostate carcinogenesis.	17724724
Inflammation, Malnutrition, Vitamin B 12 Deficiency, Anemia, Kidney Diseases	Altered Intercellular Communication	Causes of anemia were classified as due to nutritional deficiencies (iron, folate, and B12 deficiencies), anemia of chronic inflammation, anemia with renal disease, and unexplained anemia.	17726354
Inflammation, Anemia, Kidney Diseases	Altered Intercellular Communication	Of the 147 anemic women, 22 (15.0%) had anemia due to nutritional causes, 45 (30.6%) had anemia due to chronic inflammation, 29 (19.7%) had anemia and renal disease, and 51 (34.7%) had unexplained anemia.	17726354
Inflammation, Anemia, Kidney Diseases	Altered Intercellular Communication	The proportions of those who died over five years among non-anemic women and women with anemia due to nutritional causes, chronic inflammation, renal disease, and unexplained anemia were 26.1%, 18.2%, 38.6%, 64.3%, and 33.3%, respectively (p<0.0001).	17726354
Cessation of life, Inflammation, Anemia, Kidney Diseases	Altered Intercellular Communication	Compared with non-anemic women, those with anemia and renal disease (HR 1.99, 95% CI 1.18-3.35, p=0.009) and anemia of chronic inflammation (HR 1.69, 95% CI 1.00-2.84, p=0.05) had higher risk of death.	17726354
Inflammation, Anemia, Kidney Diseases	Altered Intercellular Communication	Anemia with renal disease and anemia of chronic inflammation are associated with a higher mortality.	17726354
Inflammation, Hyperphosphatemia, CTCAE, Calcinosis, Vascular calcification	Altered Intercellular Communication	Inflammation, hyperphosphatemia and lack of calcification inhibitors are uremia-associated risk factors for vascular calcification.	17726653
Inflammation, Duodenal Ulcer	Altered Intercellular Communication	Gastric inflammation correlated positively with CD4(+) and chronically activated CD4(+) T-cells in children and adults without duodenal ulcer, respectively.	17727687
Inflammation, Fever, CTCAE, Upper respiratory tract mucus	Altered Intercellular Communication	There is still a need for GPs and patients to be better informed about the limited significance of single inflammation signs (for example, fever and green phlegm) as an indication for antibiotics.	17727749
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Recurrent or persistent inflammation has emerged as an important factor in cancer development.	17728788
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inclusion criteria for the control group were absence of documented diagnosis of cancer and/or chronic inflammation within patient computerized records.	17728788
Inflammation, Periodontal Diseases, Coronary heart disease	Altered Intercellular Communication	Recent data have shown that periodontal disease may increase the risk of occurrence of coronary heart disease in which inflammation initiated by bacteria and their compounds might be a common causal factor.	17760542
Inflammation, Hemorrhage	Altered Intercellular Communication	According to the periodontal evaluation, gingival inflammation was 12.5%, bleeding on probing score was 24%, probing depths averaged 4 to 6 mm, and clinical attachment loss averaged 3 to 6 mm.	17760556
Peripheral ulcerative keratitis, Corneal Stroma, Inflammation	Altered Intercellular Communication	Peripheral ulcerative keratitis (PUK) is a disorder consisting of a crescent-shaped destructive inflammation of the perilimbal corneal stroma.	17760638
Kidney Failure, Chronic, Inflammation, Hyperparathyroidism, Necrosis, Malignant Neoplasms	Altered Intercellular Communication	We propose that those patients with ESRD who develop breast pathology consistent with inflammation and necrosis, and have no malignancy, be evaluated for secondary hyperparathyroidism.	17760676
Inflammation, Peritonitis	Altered Intercellular Communication	Procalcitonin (PCT) has recently been identified as an inflammation marker and recommended as a new potential marker in CAPD peritonitis.	17761036
Inflammation, Hemorrhage, Tissue Adhesions	Altered Intercellular Communication	Conversion to open cholecystectomy was necessary in 19 patients (10.3%); 16 patients for severe inflammation and adhesions and 3 patients because of uncontrolled bleeding.	17761084
Inflammation, Sinusitis	Altered Intercellular Communication	This guideline provides evidence-based recommendations on managing sinusitis, defined as symptomatic inflammation of the paranasal sinuses.	17761281
Cyclophosphamide/Vincristine/Dacarbazine Regimen, Coronary heart disease	Altered Intercellular Communication	These data support 4 main conclusions: (1) Elevation of hs-CRP and tHcy are common in CVD; (2) the significant relationship between tHcy and hs-CRP suggests that the association of tHcy with CVD risk may be dependent on inflammation-related mechanisms; (3) increased hs-CRP and tHcy show that patients with CVD may be at greater risk of subsequent coronary heart disease; and (4) admission hs-CRP could be used as an indicator of prognosis.	17761368
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	The driving force in the progression of COPD is the development of exacerbations which are mostly the result of excessive inflammation.	17761412
Cessation of life, vascular inflammations	Altered Intercellular Communication	Increasing vascular inflammation, as measured by CRP, increases the likelihood of death.	17761503
Hereditary Diseases, Brucellosis	Altered Intercellular Communication	Familial Mediterranean Fever is a chronic hereditary disease which is relatively prevalent in the Middle East and is associated with recurrent episodes of serosal, synovial or cutaneous inflammations.	17762405
Cataract, Acute inflammation	Altered Intercellular Communication	Rimexolone 1% versus prednisolone acetate in preventing early postoperative inflammation after cataract surgery.	17762913
Cataract, Intraocular inflammation	Altered Intercellular Communication	To compare the efficacy and safety of rimexolone 1% and prednisolone acetate 1% ophthalmic suspensions in controlling intraocular inflammation in the early period after cataract surgery.	17762913
Inflammation, Calcified (qualifier)	Altered Intercellular Communication	Histology demonstrated a partially ossified, lobulated, chondrocalcific lesion surrounded by chronic inflammation, spindle to epithelioid cells, and occasional multinucleated giant cells-all features of calcifying pseudoneoplasm of the neural axis.	17762936
Inflammation, Granulomatosis with polyangiitis, Guinea (geographic area), Infection	Altered Intercellular Communication	GIN has been associated with medications, infections, inflammation, Wegener's granulomatosis, and jejuno-ileal bypass.	17763176
Intraocular inflammation, Hemorrhage, Pseudophakia	Altered Intercellular Communication	An 80-year old pseudophakic man developed intraoperative suprachoroidal hemorrhage during a vitreous biopsy procedure for chronic intraocular inflammation.	17763245
Inflammation, Lung Abscess, Hemorrhage, Hemoptysis	Altered Intercellular Communication	When hemoptysis occurs due to sustained inflammation such as a lung abscess, bleeding from the pulmonary artery should be considered and a precise evaluation including contrast-enhanced CT and pulmonary angiography made.	17763692
Granulomatous inflammation	Altered Intercellular Communication	A lung biopsy in the first patient and a nasal biopsy in the second revealed a granulomatous inflammation, and both patients had an elevated titre of antineutrophilic cytoplasmic antibodies (ANCA), with a cytoplasmic pattern, and an elevated result of the ELISA test for antiproteinase-3 (PR3).	17763812
Inflammation, Psoriasis	Altered Intercellular Communication	Psoriasis is characterized by hyperproliferation and abnormal differentiation of keratinocytes, and inflammation.	17763859
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	HCV core protein plays important roles in HCV-related hepatocarcinogenesis, because mice carrying the core protein exhibit multicentric HCCs without hepatic inflammation and fibrosis.	17764115
Ductal Carcinoma, Comedo Necrosis	Altered Intercellular Communication	In univariate analysis, the presence of flat epithelial atypia was significantly related to ductal carcinoma in situ nuclear grade (most common in low grade, least common in high grade; P<0.0001), architectural pattern (most common in micropapillary and cribriform, least common in comedo; P<0.0001), absence of comedo necrosis (P<0.001), absence of stromal desmoplasia (P=0.02) and absence of stromal inflammation (P=0.03).	17767135
Acute sinusitis	Altered Intercellular Communication	Inflammation of paranasal sinuses: the clinical pattern is age-dependent.	17767599
Adenoma, Pituitary Neoplasms	Altered Intercellular Communication	Comparing different hormonal subtypes of noninvasive and invasive pituitary tumors, MMP-9 mRNA expression was significantly increased in the majority of invasive adenomas.	17768685
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The metabolic syndrome is associated with low-grade inflammation.	17785365
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	It has been suggested that proinflammatory cytokines and low-grade systemic inflammation activate bone resorption and may lead to reduced bone mineral density (BMD), but no previous studies have evaluated the association between the metabolic syndrome and BMD.	17785365
Renal Insufficiency, Inflammation	Altered Intercellular Communication	Resistin, a recently discovered proinflammatory cytokine, has been variably associated with insulin resistance, inflammation, and renal dysfunction.	17785630
Inflammation, Renal sclerosis with hypertension	Altered Intercellular Communication	In human hypertensive nephrosclerosis, however, there have been few studies examining the role of inflammation histologically.	17785932
Inflammation, Renal sclerosis with hypertension	Altered Intercellular Communication	In conclusion, inflammation is involved in the progression of human hypertensive nephrosclerosis and the inflammatory process is inhibited by blocking the renin-angiotensin system.	17785932
Inflammation, Retropharyngeal Abscess	Altered Intercellular Communication	Retropharyngeal abscess commonly develops among infants and small children, and is associated with the severe inflammation of the retropharyngeal lymph nodes located in the retropharyngeal space.	17785958
Inflammation, Torticollis, Spasm	Altered Intercellular Communication	The inflammation caused spasms of the prevertebral muscles, eventually leading to torticollis.	17785958
Autoimmune Diseases, Inflammation, Simultaneous	Altered Intercellular Communication	Data on gender, age, clinical features, liver biochemistries, tests of inflammation and autoimmunity, and concomitant diseases were collected.	17786140
Sjogrens Syndrome", Inflammation, Autoimmune Diseases, Systemic disease	Altered Intercellular Communication	Liver involvement is frequently found in patients with primary Sjogren's syndrome, and its presence is associated with clinical features of systemic disease, and markers of autoimmunity and inflammation.	17786140
Chronic liver disease, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Chronic liver disease is characterized by inflammation and fibrosis.	17786144
Cancer-related fatigue, Inflammation	Altered Intercellular Communication	Collectively, these data suggest that PTX3 protein may represent an additional and stable marker of inflammation in CRF.	17786277
Mucous Membrane, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Our results suggested that functional promoter polymorphisms of the MIF gene might be associated with the severity of gastric mucosal inflammation in younger subjects and with the subsequent development of mucosal atrophy.	17786285
Inflammation, Allodynia, Pain Distress Question	Altered Intercellular Communication	An essential feature of symptomatic periradicular inflammation is mechanical allodynia, defined as reduced mechanical pain thresholds.	17804314
ARCN1 gene, Inflammation, Bronchitis	Altered Intercellular Communication	Chronic bronchitis sub-phenotype within COPD: inflammation in sputum and biopsies.	17804442
Autoimmune Diseases, Inflammation, Atherosclerosis	Altered Intercellular Communication	The implication is that inflammation may be the central link between the chronic inflammatory autoimmune disorders and atherosclerosis.	17804533
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Decrease in binding for the neuropeptide VIP in response to marked inflammation of the mucosa in ulcerative colitis.	17804556
Coinfection, Communicable Diseases, Inflammation	Altered Intercellular Communication	HCMV gB-II infection and HCMV gB-II coinfection with EBV-1 are closely associated with periodontal tissue inflammation and destruction.	17804655
Pain Distress Question, Inflammation	Altered Intercellular Communication	Despite the higher pain score, most patients with pin-site inflammation report that they would repeat the procedure without anesthesia.	17805024
Inflammation, Anemia, Kidney Diseases	Altered Intercellular Communication	The proportion of adults in the lowest quartile of selenium among those who were non-anemic or who had anemia due to nutritional causes, chronic inflammation, renal disease or unexplained anemia was 9.9, 27.5, 17.5, 24.0 and 15.4%, respectively.	17805227
vascular inflammations, Coronary heart disease	Altered Intercellular Communication	These data suggest that decreasing vascular inflammation and Hcy concentration are not likely mechanisms by which soy consumption reduces coronary heart disease risk.	17805230
Tumor necrosis, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	The response to FOLFOX-4 was associated with tumour necrosis, fibrosis and inflammation.	17805566
Orthodontic, Inflammation	Altered Intercellular Communication	Orthodontic treatment of these patients is possible and would involve removal of inflammation and occlusal interference and provision of an environment for proper restorative rehabilitation.	17823683
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Systemic inflammation in non-obese children with obstructive sleep apnea.	17825619
Inflammation, Obesity, Osage language	Altered Intercellular Communication	Systemic inflammation is a constitutive component and consequence of OSA in many children, even in the absence of obesity, and is reversible upon treatment in most patients.	17825619
Chronic disease, Malignant Female Reproductive System Neoplasm	Altered Intercellular Communication	Several chronic diseases have been hypothesized to affect the risk of subsequent gynecologic malignancies, possibly through shared hormonal mechanisms.	17825884
Inflammation, Hemorrhage	Altered Intercellular Communication	No magnetic resonance image demonstrated peridural inflammation or hemorrhage.	17826275
Inflammation, Hemorrhage	Altered Intercellular Communication	Based on these observations, one should consider bleeding or peridural inflammation to be abnormal after spinal or epidural anesthesia.	17826275
SMALL PATELLA SYNDROME, Colonization, Inflammation, Calcinosis	Altered Intercellular Communication	Prostatic calcification is common in patients with CPPS and is associated with greater inflammation, bacterial colonization, and symptom duration.	17826477
Inflammation, Carcinogenesis	Altered Intercellular Communication	These results suggest that COX-2 induction begins in the premalignant phase of cervical carcinogenesis and is correlated with inflammation.	17826825
Amyotrophic Lateral Sclerosis	Altered Intercellular Communication	ITPR2 is a strong candidate susceptibility gene for ALS because it is involved in glutamate-mediated neurotransmission, is one of the main regulators of intracellular calcium concentrations, and has an important role in apoptosis.	17827064
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Activations of coagulation and fibrinolysis secondary to bowel inflammation in patients with ulcerative colitis.	17827828
Observation Method - Coagulation, Acute inflammation, Vascular occlusion, Colitis, Ischemic	Altered Intercellular Communication	On the other hand, there are no reports dealing with coagulation in ischemic colitis (IC), in which acute bowel inflammation and reversible vascular occlusion affect the colon.	17827828
Inflammation, Acute inflammation	Altered Intercellular Communication	The results of the present study indicate that the coagulation-fibrinolysis system is activated in patients with active bowel inflammation such as active UC and IC, and that the hyper states of coagulation and fibrinolysis in patients with active UC are secondary to bowel inflammation.	17827828
Inflammation, Left ventricular diastolic dysfunction, Myocardial Ischemia, Congestive heart failure	Altered Intercellular Communication	Impact of statin therapy on systemic inflammation, left ventricular systolic and diastolic function and prognosis in low risk ischemic heart disease patients without history of congestive heart failure.	17827830
Coughing, Inflammation	Altered Intercellular Communication	A challenge test of 1,1,1,2-tetrafluoroethane (HFC134a) inhalation was performed, which resulted in an elevation of body temperature, the development of a cough, and laboratory data indicating increased inflammation.	17827848
Inflammation	Altered Intercellular Communication	The method was used in 102 patients aged 8-68 years with chronic inflammation of the palatine tonsils out of exacerbation.	17828105
Inflammation	Altered Intercellular Communication	It is demonstrated that ethanol injection leads to dystrophic alteration of sympathetic ganglia and acute aseptic inflammation of para-neural tissues.	17828119
Cholelithiasis, Empyema	Altered Intercellular Communication	Complicated cholelithiasis was seen at 4310 (42.9%) patients including 792 patients with acute inflammation of gallbladder, 2375--with chronic empyema, 1143--with gallbladder hydrops.	17828135
Inflammation, Urethrorectal fistula, Traumatic injury	Altered Intercellular Communication	Rectourethral fistula is a rare complication of pelvic surgery, trauma, or inflammation.	17828402
Inflammation, Demyelination, Nerve Degeneration, Adrenal cortical hypofunction, Disease	Altered Intercellular Communication	Mutations in the ABCD1 gene encoding ALD protein (ALDP) cause this clinically heterogeneous disorder, ranging from adrenocortical insufficiency and neurodegeneration to severe cerebral inflammation and demyelination.	17828604
Inflammation, Demyelination, Meibomian gland dysfunction	Altered Intercellular Communication	ALDP-deficient mice replicate metabolic dysfunctions and develop late-onset axonopathy but lack histological signs of cerebral inflammation and demyelination.	17828604
Axonal degeneration, Inflammation, Demyelination	Altered Intercellular Communication	Routine histology revealed no signs of inflammation or demyelination in the CNS, but immunohistochemical analyses of spinal cord neuropathology revealed microglia activation and axonal degeneration in Mag and Abcd1/Mag double-knockout (ko) and, less severe and of later onset, in Abcd1 mutants.	17828604
Inflammation	Altered Intercellular Communication	The decreased expression of TNFR1, which mediates the signal for polymorphonuclear cell respiratory burst, might also contribute to the reduction of inflammation.	17845393
Airway structure, Asthma	Altered Intercellular Communication	Given the importance of airway inflammation in asthma, there has been an effort to incorporate inflammatory markers into its management.	17845587
Inflammation	Altered Intercellular Communication	The results suggest that EBV-encoded dUTPase can enhance production of proinflammatory cytokines by monocytes/macrophages in contact with endothelial cells of blood vessels, and may play a role in cardiovascular pathology and chronic inflammation.	17845840
Inflammation	Altered Intercellular Communication	To investigate the association between serum albumin, prealbumin, various serum inflammation associated-cytokines, and mortality in older geriatric recuperative care patients.	17845949
Inflammation	Altered Intercellular Communication	Subclinical inflammation appears to be an important factor contributing to low serum albumins in older recuperative care patients and may confound the association between albumin and mortality in this population.	17845949
Tumor necrosis	Altered Intercellular Communication	Clarithromycin resistance, tumor necrosis factor alpha gene polymorphism and mucosal inflammation affect H. pylori eradication success.	17846855
Inflammation	Altered Intercellular Communication	In summary, our findings provided additional evidence that the pathological stress, such as chronic inflammation, altered the expression of CD44 isoforms in oral epithelia and saliva of OLP patients.	17846873
Inflammation, diabetic	Altered Intercellular Communication	Diabetic patients were found to have higher risk for inflammation and oxidative stress.	17847112
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The relationship among chronic inflammation, innate immunity, and cancer is well established.	17848669
Malignant neoplasm of esophagus, Inflammation	Altered Intercellular Communication	The highly significant association between NTS, reflecting chronic NO-induced cellular protein damage, and endogenous p53 mutations at CpG dinucleotides, provides further evidence for a molecular link between chronic inflammation and esophageal malignancy.	17849424
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	The titre was positively correlated with patient age, prostate volume and aggressive inflammation, suggesting an involvement with benign prostatic hyperplasia (BPH).	17850358
prostatitis	Altered Intercellular Communication	These results support our hypothesis that P. acnes might be involved in the development of inflammation-related prostate diseases, in particular with BPH.	17850358
Refractory anemias, Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	Rheumatoid arthritis (RA) is characterized by chronic joint inflammation and destruction.	17850593
Schizophrenia	Altered Intercellular Communication	Accumulating evidence suggests that both homocysteine metabolism and monoaminergic neurotransmitter systems are important in schizophrenia pathology.	17851041
Parkinson Disease, Inflammation, Nerve Degeneration	Altered Intercellular Communication	Several lines of evidence suggest a role of inflammatory processes in Parkinson disease, although it is still unclear whether inflammation is a cause or rather a consequence of neurodegeneration.	17851257
Lymphoid hyperplasia, Acute inflammation	Altered Intercellular Communication	Pathologic analysis disclosed acute neutrophilic inflammation in the appendix wall in 12 of the 24 specimens and lymphoid hyperplasia in 10 of the 24 appendices.	17851689
Inflammation	Altered Intercellular Communication	Histology revealed inflammation in 75.3 percent in the early group compared with 23.8 percent in the delayed group.	17851720
Inflammation, Thrombosis, Carcinogenesis, Lip and Oral Cavity Carcinoma	Altered Intercellular Communication	In light to recently found contribution of factors associated with thrombosis and inflammation to carcinogenesis, we investigated the possible association of angiotensin I- converting enzyme (ACE) with increased risk for oral cancer.	17851834
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	These results may suggest an activated microglia induced recruitment of peripheral inflammatory cells to sites of inflammation in ALS patients.	17852013
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Correlation between two markers of inflammation, serum C-reactive protein and interleukin 6, and indices of oxidative stress in patients with high risk of cardiovascular disease.	17852073
Inflammation, physiopathological, Abnormal	Altered Intercellular Communication	Pathology of CSX may involve microvascular dysfunction related to inflammation and abnormal pain sensitivity.	17852785
Inflammation, Pain Distress Question	Altered Intercellular Communication	Kinins are labile peptides participating in vasodilation, inflammation and pain.	17852785
Inflammation	Altered Intercellular Communication	New coated and closed loop circuit systems may reduce this inflammation response and improve the surgical outcome.	17852793
Gastrointestinal inflammation	Altered Intercellular Communication	Lactoferrin as a glucoprotein that can reflect the activity of neutrophil leukocytes is a specific and sensitive indicator in the evaluation of intestinal inflammation.	17852860
Tumor necrosis, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Tissue levels of tumor necrosis factor-alpha correlates with grade of inflammation in untreated ulcerative colitis.	17852866
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	TNF-alpha is highly expressed in UC and correlates to the grade of inflammation.	17852866
Inflammation, Neoplasms	Altered Intercellular Communication	There were positive correlations between tumor grade and both the intratumoral inflammation score (IIS) and the extratumoral inflammation score (EIS) (p=0.001 and 0.01, respectively).	17853031
Inflammation, Extravasation	Altered Intercellular Communication	Serum levels of markers of brain cell leakage and inflammation remained low following one ECT session, suggesting that ECT does not cause direct brain cell leakage, nor an inflammatory response.	17853285
Inflammation, Hernia, Femoral	Altered Intercellular Communication	It is very important to bear in mind that right femoral hernia with signs of incarceration and inflammation may contain an acutely inflamed appendix.	17853718
Destruction of tissue, Inflammation	Altered Intercellular Communication	Matrix metalloproteinases (MMPs) contribute to tissue destruction, regeneration, inflammation and apoptosis and several of them are upregulated by ultraviolet (UV) radiation in skin.	17854363
Gingival Hyperplasia, Inflammation, Dental Occlusion, Traumatic	Altered Intercellular Communication	In the presence of gingival enlargement resulting from inflammation, traumatic occlusion can cause progressive external root resorption.	17868514
Inflammation, Adenocarcinoma of large intestine, Carcinoma, Necrosis	Altered Intercellular Communication	Colorectal adenocarcinoma should be considered on prostate sampling when carcinoma exhibits either "dirty" necrosis, tall columnar epithelium with mucin production, mucin-positive signet-ring cells, villous architecture, or associated inflammation.	17868775
Communicable Diseases, Inflammation	Altered Intercellular Communication	Inflammation and infection in nine surgically explanted Medtronic Freestyle stentless aortic valves.	17868876
Inflammation, Disease	Altered Intercellular Communication	CFH plays a role in inflammation, which is causal to both diseases and both are highly prevalent in old age.	17869048
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Therefore, we investigated whether or not Y402H associated with inflammation, visual acuity, and cardiovascular disease in old age.	17869048
Inflammation, Visual Impairment	Altered Intercellular Communication	We conclude that the CFH Y402H polymorphism associates with inflammation, visual impairment, and cardiovascular mortality in the elderly population at large.	17869048
Airway structure, Acute asthma, Bronchospasm	Altered Intercellular Communication	Treatment of acute asthma is based on rapid reversal of bronchospasm and airway inflammation.	17869079
Inflammation, Hemorrhage	Altered Intercellular Communication	Absence of cellular pleomorphism, low mitotic activity, dense hyalinization, hemorrhage, and chronic inflammation were observed.	17870015
Inflammation	Altered Intercellular Communication	According to our results the inflammatory activity represented by high levels of IL-6 and CRP are involved in the pathogenesis of ACD, probably due to the action of inflammation on iron metabolism, but not in ARC.	17873309
Inflammation, Communication, Traumatic injury	Altered Intercellular Communication	The main pancreatic duct can form a fistulous communication with another epithelium in the setting of prolonged inflammation, operative manipulation, or direct trauma.	17873469
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Nineteen additional patients with inflammatory bowel disease were tested to determine influence of inflammation.	17873612
Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	In all responders, healing of ulceration and resolution of inflammation occurred.	17874027
Airway structure, Diffuse panbronchiolitis, Bronchiolitis	Altered Intercellular Communication	The pathogenesis of airway inflammation in diffuse panbronchiolitis (DPB) is unknown.	17875053
Shock, Traumatic	Altered Intercellular Communication	These findings suggest that hormonal differences may play a role in the sex-based outcome disparities following traumatic shock in children.	17875843
Inflammation, Traumatic injury	Altered Intercellular Communication	End points were (1) circulating markers of inflammation and organ injury, (2) operative results, and (3) outcome at 1-year follow-up.	17875971
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The Fibrotest-Actitest is a six-parameter scoring system that allows quantification of liver fibrosis and inflammation.	17877064
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The AUROC curve comparing the Fibrotest with liver biopsy with a cutoff point at F2 and A2 for significant fibrosis and inflammation was 0.85 and 0.79 respectively.	17877064
FibroTest Score Measurement, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Fibrotest is a simple and effective method to assess liver fibrosis and inflammation and can be considered an alternative to liver biopsy in most patients with HCV.	17877064
Inflammation, Carcinoma, Cervical intraepithelial neoplasia grade 2, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	The incidence of HPV in our samples is 23.37%, 33.08%, 54.54%, 57.14%, 82.61%, 91.30% and 100% for normal cytology, inflammation,CIN I ,CIN I - II, CIN II ,CIN III, and carcinomas specimens, respectively.	17877181
Inflammation, Carcinoma, Infection, Cervical intraepithelial neoplasia grade 2, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	Infections with more that one virus are common, accounted for 4.89%, 7.14%, 18.18%, 28.57%, 41.30%, 43.37% and 38.46% for normal cytology, inflammation, CIN I, CIN I - II, CIN II, CIN III, and carcinomas specimens, respectively.	17877181
Gastrointestinal inflammation	Altered Intercellular Communication	Prospective evaluation of faecal neutrophil-derived proteins in identifying intestinal inflammation: combination of parameters does not improve diagnostic accuracy of calprotectin.	17877510
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Leptin and C-reactive protein (CRP) concentrations are increased in inflammation, and both have been linked to increased risk for cardiovascular diseases.	17878255
Granulomatous inflammation, Chronic diarrhea, Weight decreased, Colitis	Altered Intercellular Communication	We present a patient with chronic watery diarrhea and weight loss, in whom colonoscopic findings were consistent with microscopic colitis, but histopathological examination revealed granulomatous inflammation.	17878641
IVL gene	Altered Intercellular Communication	The present case suggests that hormonal disturbances may progress in advance in IVL, before generalized symptoms develop.	17878644
Vitreous Hemorrhage, Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	Repeated exacerbations of ocular inflammation with vitreous hemorrhage in a patient with HLA-B27 associated uveitis.	17878686
Intraocular inflammation, Uveitis	Altered Intercellular Communication	HLA-B27 associated uveitis is characterized by recurrent alternating acute unilateral attacks of intraocular inflammation in the anterior chamber.	17878686
Vitreous Hemorrhage, Inflammatory abnormality of the eye, Structure of central vein of the retina, Retinal Hemorrhage	Altered Intercellular Communication	He showed repeated exacerbation of ocular inflammation with retinal vein dilation and small retinal hemorrhage following vitreous hemorrhage.	17878686
Keratoconjunctivitis, Vernal, Keratitis	Altered Intercellular Communication	Vernal keratoconjunctivitis (VKC) is responsible for severe conjunctival and corneal inflammation that often requires topical steroids.	17878822
Extraocular, Inflammation	Altered Intercellular Communication	All patients whose inflammation was partially controlled or not controlled by CsA had active extraocular atopic diseases.	17878822
Inflammation, Meckel Diverticulum	Altered Intercellular Communication	We speculate that the narrow lumen between the small intestine and the diverticulum, accompanied by poor self-emptying had caused acute inflammation resulting in perforation of Meckel's diverticulum.	17879039
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Fibrosis and inflammation were seen around the dilated peripheral portal veins embolized with dead S. japonicum eggs.	17879045
Cholangiocarcinoma, Fibrosis Assessment, Inflammation, Carcinogenesis	Altered Intercellular Communication	Our search of the literature found only one other case of cholangiocarcinoma coincident with S. japonicum, suggesting that it is not a risk factor for cholangiocarcinoma, although the inflammation and fibrosis caused by the S. japonicum eggshells may predispose to carcinogenesis.	17879045
Vasculitis, Leukocytoclastic, Cutaneous, Granulomatous inflammation, Dermatitis acneiform	Altered Intercellular Communication	Histopathologic features of cutaneous WG were not limited to leukocytoclastic vasculitis; they also included acneiform perifollicular and dermal granulomatous inflammation and palisaded neutrophilic and granulomatous inflammation.	17880578
Aspergillosis, Intracranial	Altered Intercellular Communication	Invasive sino-orbital aspergillosis with intracranial invasion often may resemble inflammatory conditions.	17881994
Herpes Zoster Ophthalmicus, Necrosis of retina, Orbital Pseudotumor	Altered Intercellular Communication	An 81-year-old woman with right orbital inflammation and acute retinal necrosis following Herpes zoster ophthalmicus was evaluated and treated.	17881997
Conjunctivitis	Altered Intercellular Communication	The diagnosis may be delayed as the initial symptoms and signs (discharge, conjunctival inflammation) may easily be attributed to prosthesis wear.	17881998
Inflammation, Craniosynostosis	Altered Intercellular Communication	99mTc-MDP bone single photon emission-computed tomography (SPECT) has proven useful at identifying inflammation of bone and its use in CRS has been discussed recently.	17882912
CD55 gene, Traumatic injury	Altered Intercellular Communication	Postmenopausal hormonal imbalance, along with poor nutrition and repeated trauma led to TC in our women population.	17883044
Obstruction of biliary tree, foodborne, Fascioliasis, Hepatitis	Altered Intercellular Communication	Fascioliasis is a foodborne trematode infection that affects patients worldwide causing both liver inflammation and biliary obstruction.	17883314
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Markers of inflammation and disuse in vastus lateralis of chronic obstructive pulmonary disease patients.	17883420
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Disuse and/or local inflammation in the muscle cannot be excluded as potential influences for the decreased muscle force in patients hospitalised due to an acute chronic obstructive pulmonary disease (COPD) exacerbation.	17883420
ARCN1 gene, Inflammation	Altered Intercellular Communication	This study did not find any evidence supporting local inflammation via IL-6, IL-8 and/or TNF-alpha in the vastus lateralis muscle of COPD patients.	17883420
Inflammation, Atherosclerosis	Altered Intercellular Communication	Platelet and leukocyte activation, atherosclerosis and inflammation in European and South Asian men.	17883700
Inflammation, Myocardial Ischemia, Atherosclerosis	Altered Intercellular Communication	It is not clear therefore whether platelet activation is an indicator of IHD or a marker of generalized atherosclerosis and inflammation.	17883700
Inflammation, Atherosclerosis	Altered Intercellular Communication	The association between elevated CRP and increased PMC suggests that inflammation in relation to generalized atherosclerosis may play an important role in PMC activation.	17883700
Inflammation, Comorbidity	Altered Intercellular Communication	chronic respiratory co-morbidity and old age) as an indication to prescribe antibiotics in stead of single inflammation signs or diagnostic labels.	17883832
methyldopa, Vitreoretinal Area, Inflammation	Altered Intercellular Communication	Persistent attachment of the posterior vitreous cortex to the macula may be another risk factor for the development of exudative AMD via vitreoretinal traction inducing chronic low-grade inflammation, by maintaining macular exposure to cytokines or free radicals in the vitreous gel, or by interfering in transvitreous oxygenation and nutrition of the macula.	17884003
Inflammation, Axonal loss	Altered Intercellular Communication	We hypothesised that functional polymorphisms in CCR5 and CCL5 influence perivascular leukocyte infiltration, inflammation, axonal loss, and remyelination, and disease course.	17884183
Inflammation, Arteriosclerosis, Metabolic Diseases, Vascular Diseases, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Proliferator-activated receptor gamma agonists may play an important role in protecting against arteriosclerosis by normalizing the metabolic disorders and depressing chronic inflammation of the vascular system in patients with type 2 diabetes mellitus and serious vascular disease.	17884451
Inflammation	Altered Intercellular Communication	Serum MPO activity may help estimate the levels of oxidative stress and inflammation.	17884796
Muscle Rigidity, Myalgia, Myositis	Altered Intercellular Communication	Two patients (1.1%) had muscle pain, five patients (2.8%) had rigidity and five patients (2.8%) had muscle inflammation.	17884958
Celiac Disease, Inflammation	Altered Intercellular Communication	Celiac disease is known to produce inflammation of the duodenum and jejunum.	17885046
Laryngitis	Altered Intercellular Communication	Imaging studies were initially interpreted as supraglottitis with laryngeal inflammation, which was confirmed by direct visualization with flexible endoscopy.	17885231
Inflammation, Complication Aspects	Altered Intercellular Communication	Baseline CRP is a powerful predictor of outcome in patients undergoing CAS, which underscores the role of inflammation in the pathogenesis of embolic complications during this procedure.	17885237
Inflammation, Giant Cell Arteritis	Altered Intercellular Communication	Contrast-enhanced, high-resolution MR imaging allows noninvasive assessment of mural inflammation in giant cell arteritis with good diagnostic certainty.	17885247
Inflammation, Cardiovascular Diseases, Atherosclerosis	Altered Intercellular Communication	In further studies analyzing the role of inflammation for cardiovascular diseases and atherosclerosis, these sex differences should be considered.	17885262
Inflammation, Infection, Granuloma, Granulomatous inflammation	Altered Intercellular Communication	with its pathological finding of inflammation with granuloma is common, but infections with granulomatous inflammation are extremely rare.	17885944
Inflammation, Congenital Abnormality	Altered Intercellular Communication	We conclude that older age, which is more frequently associated with protein malnutrition, inflammation, and glucose abnormalities than is younger age, is also the important factor influencing BMD loss in dialysis patients.	17886608
Exophthalmos, Myopathy, Orbital Pseudotumor	Altered Intercellular Communication	Ophthalmopathy was classified as Nunery type 1 (orbital inflammation, proptosis, without restrictive myopathy) or Nunery type 2 (with restrictive myopathy).	17887926
Inflammation	Altered Intercellular Communication	Efficacy was assessed as a sustained decrease in RA inflammation and an amelioration of renal function.	17888205
Inflammation	Altered Intercellular Communication	RA inflammation and AA amyloidosis were improved and stabilized after 43.4 +/- 16.5 weeks.	17888205
Inflammation	Altered Intercellular Communication	Among laboratory parameters, hemoglobin level was lower in children in Group II as compared to Group I (p = 0.001), while there was no difference in parameters of inflammation.	17888228
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Recent evidence supports the important role of inflammation in atrial fibrillation (AF) after coronary artery bypass grafting (CABG) and there is growing evidence that statin has cardiac antiarrhythmic effects.	17888963
Parametrial, Inflammation	Altered Intercellular Communication	Microscopically, the vagina, cervix, endometrium, ovaries, and parametrial tissues showed innumerable deposits of paucicellular hyaline material with adjacent inflammation.	17889676
Inflammation, Leukocytosis	Altered Intercellular Communication	Laboratory tests showed inflammation and leukocytosis (12.5x10(9)/L) with 74% neutrophils.	17890135
Inflammation, Malnutrition	Altered Intercellular Communication	Malnutrition and inflammation are recognized as important predictors of poor clinical outcome in haemodialysis (HD).	17890748
Malnutrition, HD Term Type, Inflammation, muscle mass	Altered Intercellular Communication	This study was designed to estimate the relative contribution of known biological markers of inflammation, malnutrition and muscle mass in the prognosis of HD patients.	17890748
Inflammation, Gastritis	Altered Intercellular Communication	The gastritis scores of activity and inflammation were associated with the presence of babA2 in antrum specimens but not in corpus specimens.	17890898
Pharyngitis	Altered Intercellular Communication	As the throat discomfort caused by the throat inflammation improved with azulene gargling, her water intake was reduced, and the serum Na concentration returned to normal.	17891351
Pharyngitis, Polydipsia, Hyponatremia	Altered Intercellular Communication	Thus, polydipsia caused by a throat inflammation partially contributed to hyponatremia in this patient.	17891351
Pharyngitis, Polydipsia, Hyponatremia	Altered Intercellular Communication	Therefore, we concluded that polydipsia caused by the throat inflammation, plus increased ADH secretion, resulted in hyponatremia in this patient.	17891351
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Thus, whereas therapy decreases VLA-1+ T cells in rheumatoid arthritis patients, a subset is resistant and contributes to residual and recurring inflammation.	17891451
Inflammation, Kidney Diseases	Altered Intercellular Communication	The transcription factor c-Jun regulates the expression of genes involved in proliferation and inflammation in many cell types but its role in human renal disease is largely unclear.	17891746
Inflammation, Fibrosis Assessment, Kidney Diseases	Altered Intercellular Communication	Activation of c-Jun may be involved in the regulation of inflammation and/or fibrosis in human renal disease.	17891746
Inflammation, Brain Injuries, Cerebrovascular accident	Altered Intercellular Communication	Inflammation and oxidative stress are involved in brain damage following stroke, and tryptophan oxidation along the kynurenine pathway contributes to the modulation of oxidative stress partly via the glutamate receptor agonist quinolinic acid and antagonist kynurenic acid, and via redox-active compounds such as 3-hydroxyanthranilic acid.	17892481
Inflammation, Brain Injuries, Cerebrovascular accident	Altered Intercellular Communication	Together with previous evidence that inhibiting the kynurenine pathway reduces brain damage in animal models of stroke and cerebral inflammation, and that increased kynurenine metabolism directly promotes oxidative stress, it is proposed that oxidative tryptophan metabolism may contribute to the oxidative stress and brain damage following stroke.	17892481
Inflammation, bone destruction, Arthritis	Altered Intercellular Communication	Inhibition of NF-kappaB is known to be effective in reducing both inflammation and bone destruction in animal models of arthritis.	17892600
Inflammation, Gland	Altered Intercellular Communication	The endocrine cells were typically located within the deep lamina propria or muscularis mucosae and were associated with varying degrees of glandular atrophy and inflammation.	17893119
Immune dysregulation	Altered Intercellular Communication	Recent reports have suggested that the existence of associations between hormonal dysregulation and chronic upregulation of inflammatory markers, which may cause obesity-related disturbances.	17893255
Inflammation, Alternaria (fungus)	Altered Intercellular Communication	To report a case of a dendritic epithelial defect with interface inflammation associated with Alternaria sp.	17893555
Inflammation, Keratomileusis, Laser In Situ	Altered Intercellular Communication	A case report of a 46-year-old woman who presented with a dendritic epithelial defect and interface inflammation after LASIK surgery.	17893555
Inflammation, Keratitis, Herpetic, Alternaria (fungus)	Altered Intercellular Communication	After an apparent post-LASIK herpes simplex keratitis with related interface inflammation failed to respond to medical therapy, cornea culture results were positive for Alternaria fungal sp.	17893555
Herpes Simplex Infections, Inflammation, Alternaria (fungus)	Altered Intercellular Communication	Alternaria keratitis may present with a dendritic epithelial defect with interface inflammation mimicking herpes simplex virus.	17893555
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Increased production of the soluble tumor-associated antigens CA19-9, CA125, and CA15-3 in rheumatoid arthritis: potential adhesion molecules in synovial inflammation?	17893999
Communicable Diseases, Crohn Disease, Granulomatous inflammation	Altered Intercellular Communication	In biopsy material, though, the diagnosis is more challenging, as giant cells and histiocytes can be interpreted as granulomatous inflammation indicative of other conditions such as infection or Crohn disease.	17895747
Angiectasis, Inflammation, Melanosis coli, Eosinophilic disorder, Edema	Altered Intercellular Communication	Nonspecific findings included variable inflammation, eosinophilia, mild gland disarray, vascular ectasia and edema, and mild melanosis coli.	17895747
Granulomatous inflammation	Altered Intercellular Communication	Two cases were initially given a diagnosis of granulomatous inflammation.	17895747
Inflammation, Crohn Disease	Altered Intercellular Communication	The presence of giant cells in the submucosa, variable inflammation, and crypt disarray can be easily confused with Crohn disease.	17895747
Inflammation, Restenosis	Altered Intercellular Communication	Inflammation plays a pivotal role in both inestabilization of coronary atherosclerotic plaques and development of restenosis after stent placement.	17896411
Inflammation	Altered Intercellular Communication	Our results also suggest that Tregs accumulate in the CSF of RR-MS patients, in an attempt to down-regulate local inflammation in the central nervous system.	17897326
Inflammation, Fibrous	Altered Intercellular Communication	Urinary MMP activity correlated negatively with glomerular inflammation, but positively with fibrous crescents.	17898039
Inflammation	Altered Intercellular Communication	Urinary MMP-2, MMP-9, and TIMP-1 are elevated in AAV but do not reflect renal MMP expression and glomerular inflammation.	17898039
Inflammation, Bacterial Infections, Trachoma	Altered Intercellular Communication	However, disease progression to trichiasis occurs even in regions where chlamydial prevalence is currently low, which suggests that other factors, for example other bacterial infection, may also drive inflammation and scarring, particularly in the late stages of trachoma.	17898263
Inflammation	Altered Intercellular Communication	Bacterial infection of the conjunctiva is associated with inflammation, which may result in progressive scarring.	17898263
Coma, Post-Head Injury	Altered Intercellular Communication	To report on the diagnosis and management of a"firecracker" injury presenting with a post-traumatic intraocular inflammation.	17899114
Inflammation	Altered Intercellular Communication	A diagnosis of noninfectious inflammation due to heavy metals, primarily copper (=chalcosis), was made.	17899114
Dermatitis	Altered Intercellular Communication	A role for T cell-derived interleukin 22 in psoriatic skin inflammation.	17900301
Inflammation, Psoriasis	Altered Intercellular Communication	Interleukin (IL)-22 is a T cell-derived cytokine that has been reported recently to induce cutaneous inflammation in an experimental murine model of psoriasis, and to induce in vitro an inflammatory-like phenotype.	17900301
Degenerative polyarthritis, Inflammation, Asthma, Occupational	Altered Intercellular Communication	Occupational asthma (OA) may cause alterations of airways with inflammation and remodelling after cessation of exposure.	17900308
Airway structure, Degenerative polyarthritis	Altered Intercellular Communication	Some aspects of airway inflammation and remodelling persist in subjects with prior OA long after cessation of exposure even in the absence of clinical, sputum and functional abnormalities.	17900308
Inflammation	Altered Intercellular Communication	There was good correlation between CTE and pathology in regards to inflammation (Spearman's r = 0.7, P < 0.0001) and fibrostenosis (Spearman's r = 0.6, P < 0.0001) scores.	17900329
Inflammation, Lymphadenopathy	Altered Intercellular Communication	The pathological inflammation score was significantly associated with the CTE variables mucosal enhancement, wall thickness, comb sign, and adenopathy (Mantel-Haenszel chi2 P values 0.04, 0.04, <0.0001, and 0.016, respectively).	17900329
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	By logistic regression analysis, the strongest association was seen with the comb sign (OR 5.52, P < 0.001) for inflammation and the presence of stenosis (OR 5.87, P= 0.006) for fibrostenosis.	17900329
Inflammation	Altered Intercellular Communication	The in vitro model of PHA-stimulated PBLs may mimic inflammation processes observed in vivo.	17900510
Inflammation	Altered Intercellular Communication	INFL may reduce inflammation in vivo through inhibition of both monocyte and T-cell activation.	17900510
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Its role in inflammation and malignancy has been studied experimentally.	17901713
Inflammation, Osage language	Altered Intercellular Communication	OSA is associated with increased erythrocyte aggregation/adhesion, which is correlated with an increase in inflammation markers.	17904204
Inflammation, Epigastric pain, Toxic effect	Altered Intercellular Communication	While epigastric pain and histological modifications (inflammation and thickening of the gastric layers) were manifest in patients treated with 75 mg doses in the dose finding session, no clinical signs or symptoms of toxicity were recorded in those administered with 50 mg doses.	17904378
Inflammation	Altered Intercellular Communication	Increasing evidence suggests that the insulin-like growth factor (IGF)-axis may play a role in glucose metabolism and may also be associated with systemic inflammation.	17904401
Inflammation, Varicose Ulcer	Altered Intercellular Communication	Bacteriology, inflammation, and healing: a study of nanocrystalline silver dressings in chronic venous leg ulcers.	17906429
Inflammation	Altered Intercellular Communication	Increased bacterial burden and chronic inflammation are 2 factors that may prevent these chronic VLUs (CVLUs) from healing.	17906429
Inflammation	Altered Intercellular Communication	Healing was associated with a reduction in wound bacteria and neutrophilic inflammation with an associated persistent or high lymphocyte count, as determined by wound biopsy.	17906429
Inflammation	Altered Intercellular Communication	Acute inflammation was noted in 4.6%, chronic inflammation in 84.9%, and normal mucosa in 10.5% of cases.	17906906
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	This study used contrast-enhanced and fat suppression magnetic resonance imaging (MRI) to evaluate the relationship between synovial and extracapsular inflammation in PMR and early rheumatoid arthritis (RA).	17907197
Refractory anemias, Inflammation, Synovitis, Tenosynovitis	Altered Intercellular Communication	Despite degrees of synovitis and tenosynovitis comparable with those in RA, PMR-related hand disease is associated with prominent extracapsular changes, suggesting that inflammation in these tissues is more prominent than joint synovitis, which is common in both conditions.	17907197
Inflammation, Pain Distress Question	Altered Intercellular Communication	To assess high-sensitivity C-reactive protein (hsCRP) level as a measure of low-grade inflammation in relation to Modic vertebral end-plate marrow signal change on magnetic resonance imaging (MRI) in patients with chronic low back pain.	17907216
Inflammation, Pain Distress Question	Altered Intercellular Communication	Low-grade inflammation indicated by high serum hsCRP level in patients with chronic low back pain could point to Modic I signal changes.	17907216
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	This study showed that low T3 levels are independent predictors of all-cause and also cardiovascular disease mortality in biochemically euthyroid patients, perhaps due to an intimate association with inflammation.	17908160
Osteomyelitis, Inflammation	Altered Intercellular Communication	An SIJ biopsy revealed inflammation suggestive of osteomyelitis.	17908583
Alveolar, Inflammation	Altered Intercellular Communication	A lung biopsy revealed chronic inflammation without evidence of alveolar capillaritis.	17908655
Paraesophageal	Altered Intercellular Communication	Esophagoduodenoscopy revealed no esophageal leak and a CT scan revealed only mild paraesophageal inflammation.	17909535
Inflammation, Osteoporosis	Altered Intercellular Communication	Additionally, several different biochemical markers of osteoporosis and inflammation have been determined.	17909741
Airway structure, Nose Diseases	Altered Intercellular Communication	Collection of nasal secretions is important for the evaluation of upper airways inflammation in many nasal disorders.	17910326
Airway structure	Altered Intercellular Communication	This method could be used to detect nasal airway inflammation in clinical settings.	17910326
Pyoderma Gangrenosum, Ulcerative Colitis	Altered Intercellular Communication	Pyoderma gangrenosum (PG) is a rare ulcerative inflammatory condition of unknown etiology.	17910724
Inflammation, Neoplasm Metastasis, Communicable Diseases, Cyst, Thyroid Neoplasm, Carcinoma, Papillary	Altered Intercellular Communication	A focal hepatic uptake might represent a metastasis (rare in papillary carcinomas) or be related to other causes (cysts, inflammation or infection, non-thyroidal neoplasms, etc.	17910838
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	These results provide potential insights for the increased inflammation, accelerated atherosclerosis and cardiovascular risk associated with nephropathy in type 2 diabetes.	17911088
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Rapid and deep control of inflammation in rheumatoid arthritis with infliximab and its correlation with acute-phase reactants.	17911454
Inflammation	Altered Intercellular Communication	No significant correlations were found between the acute MRI scores and each of the clinical instruments and laboratory markers of inflammation.	17912578
Pain Distress Question, Inflammation, Osteopenia	Altered Intercellular Communication	Six implants failed to meet the success criteria by sustaining mesial and distal bone loss below the first implant thread; however, they remained stable and continued functioning without pain or inflammation.	17912964
Inflammation	Altered Intercellular Communication	Only the IL-18 haplotype was associated with inflammation in the peripheral blood and only with regard to circulating TNF-alpha.	17913303
Communicable Diseases, Inflammation, Paratuberculosis	Altered Intercellular Communication	paratuberculosis causes Johne's disease, a systemic infection and chronic inflammation of the intestine that affects many species, including primates.	17913930
Arterial Stiffness, Inflammation	Altered Intercellular Communication	Relationships among renal function loss within the normal to mildly impaired range, arterial stiffness, inflammation, and oxidative stress.	17913969
Myocardial	Altered Intercellular Communication	Moreover, echocardiographic changes identified during epirubicin treatment were compared with those of a series of biochemical markers of both myocardial damage and inflammation/oxidative stress.	17914082
Inflammation, Impaired	Altered Intercellular Communication	Early contractility impairment during epirubicin treatment was associated with high levels of ROS and markers of inflammation.	17914082
Necrotizing granulomatous inflammation	Altered Intercellular Communication	A biopsy of the mass disclosed a chronic granulomatous necrotizing inflammation with Langhans giant cells.	17914549
Malignant Fibrous Histiocytoma	Altered Intercellular Communication	8-Nitroguanine as a potential biomarker for progression of malignant fibrous histiocytoma, a model of inflammation-related cancer.	17914567
Inflammation, Carcinogenesis, Neoplasms	Altered Intercellular Communication	Chronic inflammation is a critical component of carcinogenesis and tumor progression.	17914567
Carcinogenesis	Altered Intercellular Communication	Reactive nitrogen and oxygen species generated by inflammatory cells form mutagenic DNA lesions, such as 8-nitroguanine, which may play an integral role in inflammation-related carcinogenesis.	17914567
Neoplasms	Altered Intercellular Communication	In conclusion, 8-nitroguanine is an excellent candidate prognostic and predictive biomarker together with HIF-1alpha in inflammation-related tumor progression.	17914567
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Noninvasive markers in the assessment of intestinal inflammation in inflammatory bowel diseases: performance of fecal lactoferrin, calprotectin, and PMN-elastase, CRP, and clinical indices.	17916108
Inflammatory Bowel Diseases, Inflammation, Ichthyosis Bullosa of Siemens, Irritable Bowel Syndrome	Altered Intercellular Communication	The aim of this study was to compare the performance of fecal lactoferrin (Lf), calprotectin (Cal), polymorphonuclear neutrophil elastase (PMN-e), as well as serum C-reactive protein (CRP) in patients with inflammatory bowel diseases (IBD) to address (a) whether these markers can differentiate IBD patients with endoscopically assessed inflammation from IBD patients without inflammation and from irritable bowel syndrome (IBS); (b) whether they correlate with endoscopic severity of inflammation; and (c) whether a combination of fecal markers with the respective disease-specific activity indices may increase the diagnostic accuracy with reference to the endoscopic severity of inflammation.	17916108
Inflammation, Ichthyosis Bullosa of Siemens, Ulcerative Colitis	Altered Intercellular Communication	UC or CD patients with active inflammation demonstrated significantly higher levels of Lf, Cal, and PMN-e in feces as well as serum-CRP when compared to patients with inactive inflammation as well as patients with IBS (all P < 0.05).	17916108
Inflammation	Altered Intercellular Communication	None of these three stool markers is consistently superior in its ability to reflect endoscopic inflammation, but all three are superior to CRP in their diagnostic accuracy.	17916108
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	A combination of the stool markers with the CRP and a disease-specific activity index in a categorical comprehensive activity index can increase the diagnostic accuracy with reference to the endoscopic inflammation in UC.	17916108
Inflammation, Ischemic stroke, Bipolar Disorder	Altered Intercellular Communication	Depressive symptoms, inflammation, and ischemic stroke in older adults: a prospective analysis in the cardiovascular health study.	17916124
Inflammation, Ischemic stroke, Bipolar Disorder	Altered Intercellular Communication	To investigate the mediator role of inflammation in any relationship between depressive symptoms and ischemic stroke.	17916124
Inflammation, Bipolar Disorder, Cerebrovascular accident	Altered Intercellular Communication	Inflammation, as measured according to CRP at baseline, did not appear to mediate the relationship between depressive symptoms and stroke.	17916124
Conjunctivochalasis, Inflammation	Altered Intercellular Communication	Inflammation plays an important role in the pathogenesis of conjunctivochalasis and is more pronounced in eyes with nasal chalasis.	17916317
Inflammation, Data types - Address	Altered Intercellular Communication	C-reactive protein (CRP), marker and mediator of inflammation, has been detected in lesions typical for the affected areas of AD brain.	17917159
Inflammation, Data types - Address	Altered Intercellular Communication	Obtained results support the notion that low-grade inflammation is present in patients with AD.	17917159
Low Back Pain, Inflammation, Fever, Spondylitis	Altered Intercellular Communication	CT scan and MRI are recommended immediately to diagnose pyogenic spondylitis, when patients has pyrexia and lumbago with laboratory data suspected inflammation during interferon therapy.	17917401
Granulomatous inflammation	Altered Intercellular Communication	Histologically, the slides reviewed showed 4 types of granulomatous inflammation that can affect the adenotonsillar tissues.	17917445
Inflammation	Altered Intercellular Communication	Older age and markers of inflammation are strong predictors of clinical events in women with asymptomatic carotid lesions.	17917609
Inflammation, Atherosclerosis	Altered Intercellular Communication	Limited information exists regarding the association between markers of inflammation, such as high-sensitivity C-reactive protein (hs-CRP) and fibrinogen, and adverse events in postmenopausal women with subclinical atherosclerosis.	17917609
Inflammation	Altered Intercellular Communication	Therefore, we investigated the prognostic impact of traditional risk factors and inflammation on adverse cardiac events in women with asymptomatic carotid lesions.	17917609
Dysmotility, Inflammation, STC1 gene, Irritable Bowel Syndrome, Gastrointestinal dysmotility, Ichthyosis Bullosa of Siemens, Chronic intestinal pseudo-obstruction, Intestinal Pseudo-Obstruction	Altered Intercellular Communication	Enteric neuropathy with mild inflammation (ganglionitis) has been described in several motility disorders including irritable bowel syndrome (IBS), enteric dysmotility (ED), slow-transit constipation (STC) and chronic intestinal pseudo-obstruction (CIPO).	17918010
Airway structure, Asthma, Allergy - Charge Type Reason	Altered Intercellular Communication	Allergy may be only one of several mechanisms triggering exacerbation of asthma or supporting chronic airway inflammation as in asthma in general.	17919144
Cessation of life, Inflammation, Heart failure, Vascular Diseases	Altered Intercellular Communication	Similarly, circulating C-reactive protein, a marker of systemic inflammation and an independent predictor of allograft vasculopathy and death in heart transplant recipients, was higher in heart transplant recipients with ischemic than with nonischemic heart failure (log-transformed, P < 0.05).	17921822
Inflammation, Electrocardiogram: myocardial infarction (finding), Necrosis	Altered Intercellular Communication	Diagnostic value of biohumoral markers of necrosis and inflammation in patients with right ventricular myocardial infarction.	17921916
Inflammation, Acute myocardial infarction, Necrosis	Altered Intercellular Communication	C-Reactive protein (CRP) is a sensitive and reliable indicator of acute inflammation and is in good correlation with creatin kinasis (CK) or the enzymes which indicate necrosis markers in acute myocardial infarction (AIM).	17921916
Inflammation, Restenosis, Necrosis	Altered Intercellular Communication	The risk factors, clinical outcome, necrosis and inflammation biomarkers (enzymes and CRP), coronary status, restenosis of stent, and intra-hospital mortality rate in the first month, as well as a long term prognosis over a period of one year, were analysed.	17921916
Inflammation, Malnutrition	Altered Intercellular Communication	Association between haemoglobin level and all-cause mortality in haemodialysis patients: the link with inflammation and malnutrition.	17921920
Malnutrition, HD Term Type, Inflammation, Anemia	Altered Intercellular Communication	The consequent anaemia could be one of the links between malnutrition and inflammation, and higher mortality in HD patients.	17921920
HD Term Type, Malnutrition, Inflammation	Altered Intercellular Communication	The study objective was to determine the relationship between Hb levels and outcome in patients undergoing HD, accounting for inflammation and malnutrition.	17921920
Inflammation, Malnutrition	Altered Intercellular Communication	We retrospectively analysed a total of 236 patients on HD between January 2003 and December 2005, classified by absence or presence of inflammation and malnutrition (defined as serum albumin levels < 40 g/L and CRP > 8mg/l).	17921920
Inflammation, Malnutrition	Altered Intercellular Communication	The Kaplan-Meier analysis showed that, irrespective of the absence or presence of inflammation and malnutrition, the all-cause mortality was higher in patients with Hb <110g/l (Log-Rank, p=0.00147; p=0.00222).	17921920
Inflammation, Malnutrition, Anemia	Altered Intercellular Communication	On the other hand, Kaplan-Meier showed that, irrespective of the absence or presence of anaemia (Hb > 110g/l and Hb < 110g/l), the all-cause mortality was higher in patients with the presence of inflammation and malnutrition (Log-Rank, p=0.00222; p=0.00263).	17921920
HD Term Type, Malnutrition, Inflammation	Altered Intercellular Communication	Our findings confirm the association of Hb levels < 110g/L with higher mortality among maintenance HD patients, especially in patients with the presence of inflammation and malnutrition.	17921920
Inflammation, Malnutrition, Anemia	Altered Intercellular Communication	Further investigation of the relationships among anaemia, inflammation and malnutrition and survival is warranted.	17921920
Inflammation, Tenosynovitis	Altered Intercellular Communication	Clinical and laboratory evaluation of patients evaluated by rheumatology suggested that the majority developed either non-inflammatory musculoskeletal symptoms or inflammation localized to tenosynovial structures.	17922185
Inflammation, Prostatic Intraepithelial Neoplasias	Altered Intercellular Communication	Specimens were scored for high-grade prostatic intraepithelial neoplasia (HGPIN), active and chronic inflammation, biopsy core length and glandular core length.	17922858
Airway Obstruction, Bronchial Hyperreactivity, Bronchitis	Altered Intercellular Communication	Asthma is a heterogeneous chronic inflammatory condition characterised by reversible airway obstruction and hyperresponsiveness associated with underlying bronchial inflammation and structural changes.	17923071
Airway Obstruction, Bronchial Hyperreactivity, Bronchitis	Altered Intercellular Communication	Asthma is a heterogeneous chronic inflammatory condition characterised by reversible airway obstruction and hyperresponsiveness associated with underlying bronchial inflammation and structural changes.	17923071
Gonadoblastoma, Neoplasms	Altered Intercellular Communication	Hormonal activity of gonadoblastoma was noted in 3 patients, with 1 tumor producing androgens.	17923202
Inflammation	Altered Intercellular Communication	This observation highlights the role of inflammation in AF and might have further prognostic and therapeutic implications.	17923414
Necrotizing granulomatous inflammation, Caseous necrosis	Altered Intercellular Communication	The histopathology demonstrated chronic granulomatous inflammation with caseous necrosis.	17923749
Pituitary Adenoma, Hormone secretion, Neoplasms	Altered Intercellular Communication	Pituitary adenomas are common neoplasms requiring medical and/or surgical treatment when associated with hormonal hypersecretion.	17923800
Deficit	Altered Intercellular Communication	Due to lack of hormonal deficits and/or compression of adjacent structures, we opted for conservative management and followup with consecutive magnetic resonance imaging.	17923800
Inflammation	Altered Intercellular Communication	Sites of inflammation in painful rheumatoid shoulder assessed by musculoskeletal ultrasound and power Doppler sonography.	17924110
Refractory anemias, Pain Distress Question, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Ultrasonography (US) and power Doppler sonography (PDS) was used to investigate causes of new onset of shoulder pain and sites of shoulder inflammation in 157 shoulders of 99 patients with rheumatoid arthritis (RA).	17924110
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	A positive correlation resulted between the magnitude of HBV-specific TNF-alpha(+) CD4(+) T cells in the liver and the degree of liver inflammation and fibrosis (P = 0.002 and P = 0.006, respectively).	17924445
Inflammation, Demyelination, "Alzheimers Disease", Data types - Address, MS gene	Altered Intercellular Communication	Chronic inflammation with microglia activation is thought to play a major role in the formation or clearance of Alzheimer's disease (AD) lesions, as well as in the induction of demyelination in multiple sclerosis (MS).	17924575
Inflammation	Altered Intercellular Communication	In MS, the cortex is severely affected by chronic, long-lasting inflammation, microglia activation, and demyelination.	17924575
Lesion, Inflammation	Altered Intercellular Communication	To what extent chronic inflammation in the cortex of MS patients influences the development of AD lesions is so far unresolved.	17924575
Inflammation	Altered Intercellular Communication	Risk factors that could contribute to further understanding of vascular pathology include markers of inflammation and growth factors.	17924848
Demyelinating Diseases	Altered Intercellular Communication	Blockade of receptors for the excitatory neurotransmitter glutamate ameliorates neurological clinical signs in models of the CNS inflammatory demyelinating disease multiple sclerosis (MS).	17924980
Airway structure, Asthma	Altered Intercellular Communication	Association between neutrophilic airway inflammation and airflow limitation in adults with asthma.	17925424
Airway structure, Inflammation	Altered Intercellular Communication	Chronic inflammation is assumed to be important, although there is limited and contradictory information about the relationship between airway inflammation and postbronchodilator FEV1.	17925424
Airway structure, neutrophilic, Asthma	Altered Intercellular Communication	In this large heterogeneous population of adults with asthma, we have shown that prebronchodilator FEV1 is associated with neutrophilic and eosinophilic airway inflammation, whereas sputum total neutrophil counts alone are associated with postbronchodilator FEV1.	17925424
Airway structure, ARCN1 gene, Asthma	Altered Intercellular Communication	This supports the hypothesis that neutrophilic airway inflammation has a role in the progression of persistent airflow limitation in asthma and raises the possibility that this progression and the development of COPD share a common mechanism.	17925424
Inflammation	Altered Intercellular Communication	We previously demonstrated that upregulation of renal inducible nitric oxide synthase (iNOS) is associated with proximal tubule injury during systemic inflammation in humans.	17926021
Hyperglycemia, Cardiac complication, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Modification of proteins to form AGE residues is significantly more enhanced in patients suffering from chronic renal disease than in hyperglycemia and is associated with increased risk for cardiovascular complications and inflammation in patients with chronic renal insuffiency.	17926233
Acid reflux, Pneumonitis, physiopathological, Bronchiolitis Obliterans	Altered Intercellular Communication	Gastroesophageal reflux is a potential cause of allograft dysfunction after lung transplantation due to microaspiration, lung inflammation, and development of bronchitis obliterans.	17926904
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Increasing age, higher ALT, higher grade of inflammation on biopsy, and HBeAg positivity predicted fibrosis.	17928090
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	18% of patients with PNALT had stage 2+ fibrosis and 34% had grade 2 or 3 inflammation.	17928090
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Overall 37% of patients with PNALT had significant fibrosis or inflammation.	17928090
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	There is significant fibrosis and inflammation in 37% of patients with PNALT and a liver biopsy should be considered in patients older than 40 with high normal ALT.	17928090
Proteinuria, Inflammation, Nephritis, Renal Insufficiency	Altered Intercellular Communication	Laboratory investigation showed markedly increased parameters of inflammation, antinuclear antibodies (ANA), a proteinuria of 3.2 g/day, mild impairment of renal function, as well as a nephritic urinary sediment.	17928969
Inflammation	Altered Intercellular Communication	Serum matrix metalloproteinase-3, a parameter of synovial inflammation, was significantly increased in PMR patients.	17929127
Pain Distress Question, Morning stiffness - joint, Structure of pelvic girdle, Musculoskeletal Pain	Altered Intercellular Communication	Polymyalgia rheumatica (PMR) is an inflammatory condition of unknown etiology characterized by diffuse pain and morning stiffness involving neck, shoulder, and pelvic girdles.	17929127
Refractory anemias, Inflammation, Disability	Altered Intercellular Communication	In conclusion, elevation of serum MMP-3 in RA patients is an indicator of inflammation, and together with RF, elevation of serum MMP-3 is a predictive marker for the progression in disability especially in female patients without corticosteroid.	17929133
Inflammation, Lymphopenia, Hypocomplementemia	Altered Intercellular Communication	Moreover, blood tests revealed inflammation, lymphopenia, hypocomplementemia, positive for anti-nuclear antibody, and elevated anti-DNA antibody level.	17929141
Rheumatoid Arthritis, Inflammation, Fatigue	Altered Intercellular Communication	To determine whether persistent severe fatigue in patients with rheumatoid arthritis can be predicted by inflammation and disability.	17931330
Inflammation	Altered Intercellular Communication	The relation with inflammation or a low level of haemoglobin, which is often assumed in clinical practice, was not found.	17931330
Lethargy, Bothered by Vomiting, Hypercalcemia, CTCAE, Neurologic (qualifier value), Muscle hypotonia, Williams Syndrome, Digestive System Disorders, Constipation	Altered Intercellular Communication	When faced with an infant presenting with digestive disorders such as vomiting and constipation, associated with neurological troubles (lethargy, hypotonia) and hypercalcemia, vitamin D intoxication should be considered after tumoral, hormonal or malformative (Williams-Beuren syndrome) causes have been eliminated.	17931839
Autoimmune Diseases, Idiopathic Inflammatory Myopathies, Myositis	Altered Intercellular Communication	The idiopathic inflammatory myopathies are systemic autoimmune diseases characterized by chronic muscle inflammation resulting progressive weakness and frequent involvement of internal organs, mainly the pulmonary, gastrointestinal and cardiac systems.	17932005
Inflammation, Acute Coronary Syndrome, Heart failure, GDC AJCC Clinical Stage Terminology, Cessation of life	Altered Intercellular Communication	Inflammation in acute coronary syndrome (ACS) can identify those at greater long-term risks for heart failure (HF) and death.	17932131
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Chronic inflammation may be a risk factor for prostate cancer.	17932345
Naegleria fowleri Infection, Primary Amebic Meningoencephalitis	Altered Intercellular Communication	Traditionally, Naegleria fowleri infections are labeled primary amebic meningoencephalitis because of prominent meningeal neutrophilic inflammation.	17932496
Necrotizing granulomatous inflammation, Granulomatous amebic encephalitis, Balamuthia	Altered Intercellular Communication	and Balamuthia mandrillaris are labeled granulomatous amebic encephalitis because of parenchymal granulomatous inflammation.	17932496
Inflammation, Balamuthia Infection, Granuloma	Altered Intercellular Communication	Balamuthia infections showed a spectrum of inflammation that ranged from primarily neutrophils to granulomas.	17932496
Inflammation, Meningoencephalitis	Altered Intercellular Communication	The spectrum of inflammation in cases of Balamuthia meningoencephalitis is broader than previously described.	17932496
Inflammation, Rupture	Altered Intercellular Communication	CPPD crystals can also be deposited in the bursae, ligaments, and tendons and generate inflammation and/or ruptures.	17932681
Inflammation, Nerve Entrapment, Hernia, Pain Distress Question	Altered Intercellular Communication	The relationship of the start of complaints with sporting activity, a positive family history for inguinal hernia, a lack of signs of inflammation and bone involvement in the laboratory and imaging studies together with a localized pain in the groin, almost immediate long-lasting disappearance of pain after infiltration of the ilioinguinal nerve allowing free motion leads to the diagnosis of inguinal hernia with nerve entrapment.	17933705
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Several lines of evidence in the literature have shown that inflammation is involved in the pathogenesis of Alzheimer's disease (AD).	17934323
Inflammation	Altered Intercellular Communication	Histological examination revealed fundic type epithelium in 58.3% of cases, H. pylori was present in 50% and chronic inflammation in 66.7%.	17934641
Intestinal metaplasia, Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	COX-2 immunoexpression in EGM was not related to gender, age, epithelium type, presence of inflammation or intestinal metaplasia, H. pylori infection, or any endoscopic finding.	17934641
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, square decimeter, Cardiovascular Diseases	Altered Intercellular Communication	Type 2 diabetes mellitus (DM2) and high blood pressure (HBP) may contribute to the development of cardiovascular disease, and inflammation may be an important factor in these diseases.	17934663
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Chronic inflammation in benign prostatic hyperplasia: implications for therapy.	17935901
Inflammation	Altered Intercellular Communication	Clinical evidences also indicate that chronic inflammation correlates with clinical progression of BPH.	17935901
Inflammation	Altered Intercellular Communication	Reducing inflammation may play a crucial role in the treatment of BPH and finally lead to a better clinical outcome.	17935901
Inflammation, Malnutrition	Altered Intercellular Communication	Increased intestinal permeability and an augmented bacterial biofilm may contribute to the origin of both chronic inflammation and malnutrition.	17936155
Inflammation, atherosclerotic	Altered Intercellular Communication	The atherosclerotic risk profile, inflammation markers and main liver function tests were also studied in all patients.	17936225
Loss, Inflammation, ELN gene	Altered Intercellular Communication	Sections were taken from the anterior, posterior, greater and lesser curvature of the aorta and graded in a semi-quantitative fashion for the degree of elastin fragmentation, elastin loss, smooth muscle cell (SMC) loss, intimal changes and inflammation.	17938162
Inflammation, Tissue injury, Dental Plaque	Altered Intercellular Communication	In the present study we explored the contribution of IFN-alpha to inflammation and tissue injury in the plaque microenvironment.	17938289
Inflammation, Gastritis, Obesity	Altered Intercellular Communication	Mucosal cytokines may be involved in the process of gastric bacterial contamination that may occur after Roux-en-Y bypass for morbid obesity in both gastric chambers, with inflammation and gastritis mostly in the excluded stomach.	17938310
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	It is often considered as a potential mediator between chronic inflammation and cardiovascular diseases.	17938521
Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome, Hypothyroidism	Altered Intercellular Communication	Infliximab can induce a prolonged clinical remission and a decrease in thyroid hormonal requirements in a patient with SAPHO syndrome and hypothyroidism.	17938987
Fatty Liver	Altered Intercellular Communication	Subjects with fatty liver on US had a greater prevalence of body mass index (BMI) > or =25 kg/m2, inflammation-necrosis grade >2, and total bilirubin <1.2 mg/dl in multivariate analyses.	17939048
Steatohepatitis	Altered Intercellular Communication	Besides hepatic steatosis, clinicians should be alert to the possibility of advanced necrosis-inflammation grade in interpreting a report of bright liver on gray-scale US.	17939048
Primary malignant neoplasm, Gastrointestinal inflammation	Altered Intercellular Communication	Case report: severe gastrointestinal inflammation and persistent HHV-6B infection in a paediatric cancer patient.	17939902
Diarrhea, Gastrointestinal inflammation, Failure (biologic function)	Altered Intercellular Communication	HHV-6B infection caused or triggered severe gastrointestinal inflammation with intractable diarrhoea and failure to thrive over several months.	17939902
Inflammation, Chlamydia, Atherosclerosis	Altered Intercellular Communication	Chlamydia pneumoniae accompanied by inflammation is associated with the progression of atherosclerosis in CAPD patients: a prospective study for 3 years.	17940057
Kidney Failure, Chronic, Inflammation, Atherosclerosis, Communicable Diseases, Chlamydia	Altered Intercellular Communication	The causes of accelerated atherosclerosis in end-stage renal disease (ESRD) patients are unknown, although recent studies have suggested that Chlamydia pneumoniae (Cp) infection and inflammation might be contributing factors.	17940057
palladium, Carotid Atherosclerosis, Inflammation	Altered Intercellular Communication	We aimed to evaluate the association of carotid atherosclerosis progression with Cp infection and inflammation in patients undergoing peritoneal dialysis (PD).	17940057
palladium, Inflammation	Altered Intercellular Communication	Our data showed that Cp and inflammation were significant risk factors of CCA-IMT change in PD patients.	17940057
Inflammation, Lymphoproliferative Disorders, Deficient Food Intake	Altered Intercellular Communication	It is possible that chronic inflammation, profound immunosuppression, and nutritional deficit could lead to development of high-grade B-cell lymphoproliferative disorders.	17940628
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic airway inflammation, a major feature of chronic obstructive pulmonary disease (COPD), is associated with an activation of inflammatory and resident cells, which in turn makes them more prompt to respond to further stimuli.	17941910
Inflammation, Nasal Polyps, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) with nasal polyps (NP) represents a persistent inflammation often characterized by local hyper-immunoglobulinaemia and the presence of specific IgE to Staphylococcus aureus enterotoxins (SAEs).	17941912
Inflammation	Altered Intercellular Communication	Metastatic process could be facilitated by Batson's plexus, through the periodontal inflammation or the direct bronchotracheal way.	17942337
Refractory anemias, Inflammation	Altered Intercellular Communication	Since it has been reported that the ephrin/Eph receptor system plays important signaling roles in inflammation processes, we attempted to examine ephrinB molecules in T cells and synovial cells derived from RA in this study.	17942634
Sepsis, Inflammation	Altered Intercellular Communication	ADAMTS-13 levels were significantly associated with differences in morbidity, mortality, and variables of inflammation and endothelial dysregulation only in severe sepsis patients.	17944029
Inflammation, Rheumatic mitral stenosis, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Relationship between inflammation and atrial fibrillation in patients with isolated rheumatic mitral stenosis.	17944117
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	Although recent data have suggested that the inflammatory process is associated with non-valvular AF, the relationship between inflammation and AF occurrence in MS patients remains unknown.	17944117
Inflammation, Malnutrition, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Patients with chronic kidney disease (CKD) develop a progressive picture of malnutrition and inflammation that lead them to an elevated risk of cardiovascular disease.	17944585
Parasite Present, Communicable Diseases, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	The present results suggest that (i) the inflammatory process is intense in cutaneous ATL lesions and maintains a similar activity for several months; (ii) the dynamics of cell infiltration change during this period, with a gradual decrease in CD8+ T cells, probably correlated with a reduction in the parasite number; (iii) neutrophils may participate in the inflammatory process even during later stages of infection; (iv) the relative increase in the number of CD4+ T cells associated with the onset of fibrosis may suggest a participation of these cells in the control of the inflammatory process; and (v) late lesions with tendency for healing usually show focal inflammation.	17944980
Inflammation, Iridocyclitis, Corneal Opacity	Altered Intercellular Communication	Iridocyclitis is an inflammation of the iris (the colored part of the eye), while corneal haze is a complication of refractive surgery characterized by the cloudiness of the normally clear cornea.	17945937
Inflammatory abnormality of the eye	Altered Intercellular Communication	AMT dressing may be successfully used to reduce ocular inflammation, promote epithelialisation and prevent ocular cicatrisation.	17947270
Airway structure, Asthma	Altered Intercellular Communication	Clarithromycin targets neutrophilic airway inflammation in refractory asthma.	17947611
Inflammation, Pulmonary Eosinophilia	Altered Intercellular Communication	These reductions in inflammation were most marked in those with refractory noneosinophilic asthma.	17947611
Airway structure, Inflammation, Asthma	Altered Intercellular Communication	Macrolide therapy may be an important additional therapy that could be used to reduce noneosinophilic airway inflammation, particularly neutrophilic inflammation, in asthma.	17947611
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Increasing evidence supports a propensity towards inflammation in Alzheimer's disease (AD) pathogenesis.	17949824
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Increase in systemic vascular resistance during acute mental stress in patients with rheumatoid arthritis with high-grade systemic inflammation.	17949887
Degenerative polyarthritis, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Cardiovascular activity was measured during rest, stress, and recovery in rheumatoid arthritis patients with high systemic inflammation (C-reactive protein >8 mg/l), rheumatoid arthritis patients with low systemic inflammation (C-reactive protein	17949887
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Systemic vascular resistance increased only in rheumatoid arthritis patients with high systemic inflammation.	17949887
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Thus, acute cardiovascular events in rheumatoid arthritis patients may be related to stress-induced increases in systemic vascular resistance, particularly in patients with high levels of systemic inflammation.	17949887
Achalasia, Inflammation	Altered Intercellular Communication	Variations in inflammation and nerve fiber loss reflect different subsets of achalasia patients.	17950090
Aggressive course, Inflammation	Altered Intercellular Communication	Group B, with no inflammation, had greater loss of nerve fibers in the muscularis propria versus Group A, and therefore, may represent more aggressive disease with shorter duration of symptoms.	17950090
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	At surgery, there was tendon and bursal inflammation with fibrosis in 28 shoulders and a small rotator cuff tear in 4.	17950628
Musculoskeletal, Musculoskeletal Pain	Altered Intercellular Communication	The systemic disease of polymyalgia rheumatica may begin with local signs caused by peripheral musculoskeletal inflammation.	17950651
Carotid Atherosclerosis, Inflammation	Altered Intercellular Communication	Serum CEA was associated with carotid atherosclerosis independently of atherogenic risk factors and markers of inflammation.	17951321
Inflammation, Endophthalmitis, CTCAE, thromboembolic	Altered Intercellular Communication	No adverse events were observed, including endophthalmitis, inflammation and increased intraocular pressure or thromboembolic events in any patient.	17951903
Inflammation	Altered Intercellular Communication	Chronic inflammation and T cell zeta-chain downregulation in hemodialysis patients.	17951997
HD Term Type, Inflammation	Altered Intercellular Communication	All the evaluated markers of inflammation were increased in HD patients.	17951997
HD Term Type	Altered Intercellular Communication	Like in other pathological chronic inflammatory conditions, T cell zeta-chain is downregulated in HD patients.	17951997
Inflammation, Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome, Bone structure of spine	Altered Intercellular Communication	Diagnosing active inflammation in the SAPHO syndrome using 18FDG-PET/CT in suspected metastatic vertebral bone tumors.	17952557
Inflammation, Actinomycosis	Altered Intercellular Communication	Histological analysis showed a fibro-productive inflammation with an actinomycotic etiology.	17953250
Inflammation, infected cyst	Altered Intercellular Communication	Fine-needle aspiration cytology revealed acute inflammation, consistent with an infected cyst.	17954425
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Benign lesions with increased FDG uptake are found in more than 25% of the PET/CT studies performed in patients with proven or suspected malignancy, with inflammation being the most common cause.	17954662
Tuberculosis, Osteoarticular, Inflammation, Brucellosis	Altered Intercellular Communication	We emphasise the importance of considering brucellosis in patients returning from a stay in a rural area of an endemic country, who present with osteoarticular symptoms and signs of chronic inflammation.	17954956
Endometriosis	Altered Intercellular Communication	While speculative, in utero cigarette exposure may be associated with a lower risk of surgically diagnosed adult-onset endometriosis, possibly as a result of alterations in hormonal milieu or pathologic angiogensis.	17956923
Inflammation	Altered Intercellular Communication	The magnitude of inflammation within the wall of the large arteries increases with aging.	17957367
Pseudocyst, Inflammation	Altered Intercellular Communication	The EUS-guided treatment was effective for improvement of severe inflammation of the pseudocyst as an initial treatment.	17957965
Inflammation, West Nile Fever	Altered Intercellular Communication	Old peripheral chorioretinal lesions without active inflammation in both eyes were consistent with WNV infection.	17958570
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Inflammation, oxidative stress and apoptosis, which are involved in chronic obstructive pulmonary disease (COPD) pathogenesis, may activate the p38 subgroup of mitogen-activated protein kinases (MAPKs).	17959643
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Activated pancreatic stellate cells (PSCs) play an important role in pancreatic fibrosis and inflammation, where oxidative stress is implicated in the pathogenesis.	17962358
Intraocular inflammation, Corneal edema	Altered Intercellular Communication	The most common immediate sequelae of DNFV were intraocular inflammation (85%), corneal oedema (55%) and an intraocular pressure >30 mm Hg (34%).	17962391
Vascular Diseases, Inflammation, Hyperintensity of cerebral white matter on MRI, Endothelial dysfunction, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease is a risk factor for vascular disease and has been associated with inflammation and endothelial dysfunction, which have been implicated in the pathogenesis of white matter hyperintensities.	17962588
Inflammation	Altered Intercellular Communication	Puncture of the implant violates the tissue-implant barrier and induces inflammation or introduces bacteria that are not detectable in culture but may contribute to inflammation in the presence of the filler material.	17962993
Acute myocardial infarction	Altered Intercellular Communication	We examined the serum levels of interferon-gamma-inducible protein 10 (IP-10), an inflammation-induced chemokine, in acute myocardial infarction (AMI).	17963704
Inflammation	Altered Intercellular Communication	By virtue of its strong correlation to plasma TNF-alpha, F11R may be an important mediator of the effects of inflammation on the vessel wall.	17964041
Pain Distress Question, Foreign body sensation, Inflammation	Altered Intercellular Communication	Analysis included subjective complaints (burning, itching, foreign-body sensation, pain level after surgery) and objective findings (visual function, degree of inflammation in the anterior segment, complications).	17964399
Inflammation	Altered Intercellular Communication	The between-group differences in visual outcomes and anterior chamber inflammation were not statistically significant (mean P = .33).	17964399
Inflammation, Obesity	Altered Intercellular Communication	Obesity is a state of chronic low-grade inflammation that predisposes people to several diseases and that is increasingly prevalent.	17965124
Chronic lymphocytic inflammation	Altered Intercellular Communication	All specimens showed marked sinusoidal dilatation, and 14 showed bile ductular proliferation; 1 showed minimal iron deposition, and 1 showed mild lobular lymphocytic inflammation.	17965217
Inflammation, Fibrosis Assessment, Liver damage	Altered Intercellular Communication	No inflammation or hepatocellular damage is evident, suggesting that fibrosis may be mediated by a non-inflammatory mechanism.	17965217
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Blocking the receptor for C5a in patients with rheumatoid arthritis does not reduce synovial inflammation.	17965442
Refractory anemias, Inflammation	Altered Intercellular Communication	The data suggest that C5aR blockade does not result in reduced synovial inflammation in RA patients.	17965442
Inflammation, Berry Aneurysm, Neoplasms	Altered Intercellular Communication	Histological examination of the excised specimen revealed a saccular aneurysm and absence of bacteria, inflammation, or neoplasm.	17965565
Airway structure, Inflammation	Altered Intercellular Communication	Exhaled nitric oxide (eNO) is noninvasive parameter useful on estimation of airways inflammation, especially useful in monitoring of asthma inflammation.	17966098
Inflammation, Observation Method - Coagulation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Interplay between coagulation and inflammation in open and endovascular abdominal aortic aneurysm repair--impact of intra-aneurysmal thrombus.	17966749
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Markers of coagulation and inflammation were studied preoperatively, at one, two, three, four and seven days and at three months postoperatively.	17966749
Atrial Fibrillation, vascular inflammations, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Statins have important pleiotropic effects and have been shown to reduce vascular inflammation and the incidence of atrial fibrillation (AF) after cardiac surgery.	17967597
Inflammation	Altered Intercellular Communication	The arbitrary division of the normal healing process into the phases of hemostasis, inflammation, proliferation, and maturation addresses the events in acute wound healing.	17967618
Airway Obstruction, Pneumonitis	Altered Intercellular Communication	Pulmonary inflammation, levels of proinflammatory cytokines/chemokines (RANTES, gamma interferon, and monocyte chemoattractant protein 1) and airway obstruction were also significantly decreased in HRA2-treated mice.	17967906
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation.	17968929
Refractory anemias, Inflammation, Infiltration, Arterial Hypervascularization	Altered Intercellular Communication	In RA, the expression levels of PAD-2 and PAD-4 were correlated with the intensity of inflammation (cell infiltration, hypervascularization, and synovial lining hyperplasia), and both enzymes were demonstrable within or in the vicinity of citrullinated fibrin deposits.	17968929
Inflammation, Brain Injuries	Altered Intercellular Communication	Inflammation in human brain injury: intracerebral concentrations of IL-1alpha, IL-1beta, and their endogenous inhibitor IL-1ra.	17970618
Inflammation, Acute and chronic inflammation	Altered Intercellular Communication	Xanthogranulomatous inflammation is a rare, chronic destructive inflammatory lesion.	17970978
intraepithelial, Inflammation	Altered Intercellular Communication	In the 136 patients examined with colposcopy, inflammation was found in 47 cases, low-grade intraepithelial lesion in 53 cases, High-grade intraepithelial lesion in 36 cases.	17971942
intraepithelial, Inflammation	Altered Intercellular Communication	The pathological results show inflammation in 55 cases, low-grade intraepithelial lesion in 41 cases, High-grade intraepithelial lesion in 40 cases (Kappa=0.314, U=0.064, P less than 0.05).	17971942
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Inflammation during active UC thus causes an upregulation of cIAP2 in regenerating epithelium, which renders the cells less susceptible to Fas ligation.	17972100
Adrenal Cortex Hormones, Inflammation	Altered Intercellular Communication	Azathioprine was administered in cases with corticosteroid intolerance or uncontrolled inflammation.	17972222
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	The role of inflammation, a key event in the outcome of cirrhosis, has never been studied in this setting.	17972337
ARCN1 gene, Inflammation	Altered Intercellular Communication	Does the expired-air carbon monoxide level reflect the severity of inflammation in COPD?	17972536
ARCN1 gene, Inflammation	Altered Intercellular Communication	We assumed that the level of expired-air carbon monoxide may not useful in assessing the severity of inflammation in COPD (Tab.	17972536
Airway structure, Asthma	Altered Intercellular Communication	[Effect of dongchong xiacao capsule on airway inflammation of asthmatic patients].	17972591
Inflammation, Hypothermia due to exposure, Traumatic injury	Altered Intercellular Communication	Such unphysiological replacement has been reported in association with local trauma, inflammation, systemic diseases, and hypothermia.	17973890
Inflammation, Nerve Degeneration	Altered Intercellular Communication	This suggests that neurodegeneration, rather than primary inflammation, at least partially explains the findings.	17974617
Hyperactive behavior	Altered Intercellular Communication	The results could reflect permanent alterations of dopaminergic neurotransmission and have implications for the etiology of clinical hyperactivity.	17974717
Sleep-Disordered Breathing, Virus Diseases	Altered Intercellular Communication	Early viral infections and other immune-mediated responses may contribute to development of the chronic inflammation of the upper airway and hypertrophic upper airway lymphadenoid tissues underlying childhood sleep-disordered breathing.	17974740
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	Association between plasma LDL particle size, valvular accumulation of oxidized LDL, and inflammation in patients with aortic stenosis.	17975118
Refractory anemias, Myocarditis, Hypoalbuminemia	Altered Intercellular Communication	In addition to pericardial inflammation due to more severe RA, hypoalbuminemia was an important factor associated with the presence of asymptomatic PE.	17975311
Inflammation, Sarcoidosis	Altered Intercellular Communication	Activated CD4+ T cells accumulate in the lungs of individuals with sarcoidosis and are considered to be of central importance for inflammation.	17975675
Inflammation, Ischemia	Altered Intercellular Communication	A transient form was described secondary to drug intoxication, electrolyte imbalance, cardiac inflammation, and ischemia.	17976091
Inflammation	Altered Intercellular Communication	There was no significant difference in the degree of inflammation among the clinical groups.	17976158
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	An association between type 2 diabetes mellitus and inflammation has been described in several studies.	17976964
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	In conclusion, low-grade chronic inflammation, as estimated by the relative levels of inflammatory cytokines, was present in patients with type 2 diabetes that were receiving insulin treatment, with significantly higher cytokine levels recorded compared to sulfonylurea-treated patients.	17976964
Inflammation, Obesity	Altered Intercellular Communication	In addition, an association between inflammation and both obesity and glucose homeostasis was detected.	17976964
Refractory anemias, Inflammation, Hyperplasia, Congenital stationary cone dysfunction	Altered Intercellular Communication	These results indicate that mutations and consequent dysfunction of P53 gene may result in chronic inflammation and hyperplasia in RA patients.	17977211
Refractory anemias, Rheumatoid Arthritis, Degenerative polyarthritis	Altered Intercellular Communication	Over expression of P53 has been described in many inflammatory conditions including rheumatoid arthritis (RA) and osteoarthritis (OA) as a protective mechanism to induce apoptosis of synovial cells.	17977211
Inflammation, Pouchitis	Altered Intercellular Communication	Symptomatic pouch inflammation (pouchitis) appeared in 7-40% of the patients.	17977440
Inflammation, Thrombophilia	Altered Intercellular Communication	Inflammation and related hypercoagulability might particularly contribute to atherothrombotic events in a setting of decreased HRV.	17977694
Inflammation, Alopecia	Altered Intercellular Communication	In principle, increased expression of some IL-6 cytokine family members in cutaneous inflammation might contribute to the promotion of hair loss.	17979974
Airway structure, Asthma	Altered Intercellular Communication	In asthma patients, dietary soy isoflavone supplementation reduces eosinophil LTC(4) synthesis and eosinophilic airway inflammation.	17979994
Cataract, Communicable Diseases, Inflammation	Altered Intercellular Communication	To compare the efficacy and safety of a combined 0.5% moxifloxacin and 0.1% dexamethasone formulation (Vigadexa) versus conventional dosing with 0.5% concomitant moxifloxacin (Vigamox) and 0.1% dexamethasone (Maxidex) for the prevention of infection and control of inflammation after cataract surgery.	17980093
Intraocular Infection, Inflammation	Altered Intercellular Communication	There was no sign of intraocular infection at any time and only minimal inflammation beyond day 3.	17980093
Crohn Disease, Inflammation	Altered Intercellular Communication	Soluble angiogenic factors could be altered in patients with Crohns disease (CD), since inflammation and angiogenesis may play a critical pathogenic role.	17980128
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Inflammatory disorder, Crohn Disease	Altered Intercellular Communication	Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory disorder characterized by intractable inflammation specific to the gastrointestinal tract.	17980669
Inflammation, Fatty degeneration	Altered Intercellular Communication	Hepatic histology was near-normal in tx-j mice at 3-4-months-old and showed mild inflammation and steatosis at 6-months-old.	17981064
Electrocardiogram: myocardial infarction (finding), Ischemic stroke	Altered Intercellular Communication	Variation in inflammation-related genes and risk of incident nonfatal myocardial infarction or ischemic stroke.	17981284
Inflammation, Synovitis, Edema of bone marrow, Damage, Tenosynovitis	Altered Intercellular Communication	MRI findings reflecting inflammation (synovitis, bone marrow oedema and tenosynovitis) decreased during follow-up, while there was a small increase in MRI erosion score and CR damage.	17981915
Inflammation	Altered Intercellular Communication	A critical question remains whether the development of ectopic lymphoid tissue (ELT) in chronic inflammation recapitulates the features of SLOs.	17982129
Hemorrhagic, Erythema, Inflammation, Necrosis	Altered Intercellular Communication	On the lateral aspect of her right ankle there was an hemorrhagic, necrotic bullous lesion measuring 3 x 4 cm, surrounded by cutaneous inflammation and erythema.	17982610
Pyoderma Gangrenosum	Altered Intercellular Communication	Biopsy showed a neutrophilic abscess-like ulcerative skin inflammation, which was diagnosed as pyoderma gangrenosum.	17982610
Inflammation, Neoplasms, Necrosis	Altered Intercellular Communication	TNFalpha was initially described as inducing necrotic death in tumors in vivo, and more recently as a cytokine that mediates cytoprotection and inflammation.	17982679
Inflammation, Glomus tympanicum	Altered Intercellular Communication	The overall image quality was graded (0-2) regarding assessment of signs of tympanic membrane inflammation.	17983668
Inflammation	Altered Intercellular Communication	DMBT1 may play a role in intestinal mucosal protection and prevention of inflammation.	17983803
Inflammation	Altered Intercellular Communication	Part B: HBD1 showed a constitutive expression in mesothelium, while HBD2 and HNP1,3 were associated with inflammation.	17984427
Pituitary Adenoma	Altered Intercellular Communication	Elevation of choline peak in functional pituitary adenomas could represent an active marker of cellular proliferation, compatible with increased hormonal activity.	17984954
Inflammation, Coronary heart disease	Altered Intercellular Communication	Inflammation a possible link between economical stress and coronary heart disease.	17985199
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	To assess the relationship between economical stress, as an indicator of SES, and inflammation in women patients with coronary heart disease (CHD).	17985199
palladium, Inflammation	Altered Intercellular Communication	Our findings may suggest a recruitment of activated monocytes, macrophages and T lymphocytes to sites of inflammation in the central nervous system of PD patients.	17986095
Inflammation, myocardial injury	Altered Intercellular Communication	Baseline measurements of TnT (associated with myocardial injury, positive, if > or =0.1 ng mL(-1)), CRP (a marker of inflammation), NT-proBNP (associated with left ventricular (dys)function) and fibrin D-dimer (and index of thrombogenesis) were performed.	17986200
Rheumatoid Arthritis, Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Atherosclerotic disease is increased in recent-onset rheumatoid arthritis: a critical role for inflammation.	17986352
Vascular Diseases, Inflammation, Atherosclerosis, Refractory anemias, Coronary Arteriosclerosis	Altered Intercellular Communication	Furthermore, given the strong relationship of vascular disease to RA mortality and of inflammation to the accelerated atherosclerosis associated with RA, it is important to evaluate indices that could serially and noninvasively quantify atherosclerotic disease in RA patients.	17986352
Refractory anemias, Inflammation	Altered Intercellular Communication	Since inflammation has been shown to predate onset of clinical RA, the accelerated atherogenic process related to inflammation may precede RA symptom onset.	17986352
Microalbuminuria, Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Association of low-grade inflammation and platelet activation in patients with hypertension with microalbuminuria.	17988217
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	In conclusion, sCD40L levels appear to discriminate a subset of patients characterized by MA and low-grade inflammation, suggesting that inhibition of the CD40/CD40L system may represent a potential therapeutic target in subjects with hypertension at a high risk of cardiovascular events.	17988217
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	We performed an intention-to-treat analysis, comparing the incidence of IR and VS. We also analyzed several biological parameters related to inflammation, coagulation, and fibrinolysis systems.	17988379
Inflammation, Data types - Address	Altered Intercellular Communication	A body of evidence indicates that inflammation plays a pivotal role in AD pathogenesis.	17988833
Inflammation, Myositis, Polymyositis, Dermatomyositis, Paresis	Altered Intercellular Communication	Polymyositis and dermatomyositis are autoimmune inflammatory myopathies characterized by muscle weakness and inflammation.	17988919
Airway structure, ARCN1 gene	Altered Intercellular Communication	Persistent and severe small airway inflammation was observed in the lungs of ex-smokers with very severe COPD.	17989120
Communicable Diseases, Inflammation	Altered Intercellular Communication	Induced sputum in the very young: a new key to infection and inflammation.	17989149
Communicable Diseases, Inflammation, Lung diseases, Cystic Fibrosis	Altered Intercellular Communication	Chronic inflammation and infection in patients with cystic fibrosis (CF) and other lung diseases begin early, making noninvasive diagnostic techniques vital.	17989149
Epithelial hyperplasia, polyps, Inflammation	Altered Intercellular Communication	Most of these reports only describe chronic inflammation within the lamina propria of the polyp, with only rare reports specifying the presence of epithelial hyperplasia.	17990926
Neoplasms	Altered Intercellular Communication	The tumor is very rare, its pathogenesis is not clear, and its hormonal activity has been subject to debate.	17990931
Inflammation, Aggressive behavior	Altered Intercellular Communication	Association of extent and aggressiveness of inflammation with serum PSA levels and PSA density in asymptomatic patients.	17991548
prostatitis	Altered Intercellular Communication	The relationship between serum prostate-specific antigen (PSA) levels and histologic prostatic inflammation is controversial.	17991548
Inflammation, Aggressive behavior	Altered Intercellular Communication	The extent and aggressiveness of inflammation were analyzed.	17991548
Inflammation, Aggressive behavior	Altered Intercellular Communication	The patients were divided into groups using five grades for the extent and four grades for the aggressiveness of inflammation.	17991548
Inflammation	Altered Intercellular Communication	However, a negative correlation was found between the extent of inflammation grade and %fPSA (r = -0.268, P = 0.015).	17991548
Inflammation, Aggressive behavior	Altered Intercellular Communication	The aggressiveness of inflammation grade correlated positively with the serum PSA level (r = 0.386, P <0.001) and PSAD (r = 0.341, P = 0.001) and negatively with %fPSA (r = -0.289, P = 0.03).	17991548
Inflammation	Altered Intercellular Communication	If the elevation of serum PSA is thought to be caused by histologic inflammation, it might prevent unnecessary repeated biopsies.	17991548
Inflammation, Coronary Artery Disease, Atherosclerosis	Altered Intercellular Communication	Effect of high-dose alpha-tocopherol supplementation on biomarkers of oxidative stress and inflammation and carotid atherosclerosis in patients with coronary artery disease.	17991651
Inflammation	Altered Intercellular Communication	Oxidative stress and inflammation are crucial in atherogenesis.	17991651
Inflammation, Overweight	Altered Intercellular Communication	Associations between healthy eating patterns and immune function or inflammation in overweight or obese postmenopausal women.	17991658
Inflammation, Overweight	Altered Intercellular Communication	Our results provide limited evidence that healthy eating patterns contribute to enhanced immune function and reduced inflammation in overweight and obese postmenopausal women.	17991658
Acute Coronary Syndrome, Inflammation, Myocardial Infarction, Cerebrovascular accident	Altered Intercellular Communication	In acute coronary syndromes, the early risk of stroke relates to both heightened inflammation and size of myocardial necrosis.	17991875
Pain Distress Question, Infection - suppurative, Inflammation	Altered Intercellular Communication	Besides the known cosmetic implications, pincer nails are often complicated by pain, chronic inflammation and recurrent suppurative infections.	17993297
Osteomyelitis, Inflammation	Altered Intercellular Communication	Regular radiographic assessments may be useful in the management of patients with chronic inflammation or recurrent paronychias secondary to pincer nails to detect osteomyelitis.	17993297
Inflammation	Altered Intercellular Communication	Inflammation was graded according to the updated Sydney-system.	17993370
Barrett Esophagus, Inflammation	Altered Intercellular Communication	Compared to patients with Barrett's esophagus, the active (p=0.0002) and chronic inflammation (p=0.0004) at the squamocolumnar junction was higher in patients with a normal Z-line and frequently accompanied by lymphoid aggregates (p<0.0001) and regular cardia- (p=0.0044) and/or corpus-type glands (p=0.0004).	17993370
Inflammation	Altered Intercellular Communication	Cytological specimens were characterized by a background containing abundant mucin in all cases and rarely by inflammation (neutrophils and histiocytes) (n=4).	17993724
vascular inflammations, Grade A1 albuminuria, Nephritis, Hypercholesterolemia, Familial	Altered Intercellular Communication	These results collectively indicate that pravastatin may ameliorate systemic vascular inflammation rather than local renal inflammation in hyperlipidemic type 2 diabetic patients with normoalbuminuria, independent of its cholesterol-lowering effects.	17994445
Inflammation, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	High prevalence of malnutrition and inflammation in undialyzed patients with chronic renal failure in developing countries: a single center experience from eastern India.	17994448
Cancer-related fatigue, Inflammation, Malnutrition	Altered Intercellular Communication	There is a paucity of data on the quantification of malnutrition and inflammation in undialyzed patients of CRF from India.	17994448
Fibrosis Assessment, Tubular atrophy, Interstitial inflammation	Altered Intercellular Communication	The viral cytopathic changes, interstitial inflammation, fibrosis and tubular atrophy were semiquantitatively assessed, based on the Banff 1997 classification and scoring for renal allograft.	17995590
Aneurysmal, Inflammation	Altered Intercellular Communication	Although this implicates inflammation as a cause of AAAs, there is also evidence that the aneurysmal aorta may secrete IL-6 into the circulation as a result of aortic proteolysis.	17996468
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	Elevations in CRP, a measure of systemic inflammation, have been associated with aortic stenosis.	17996566
Inflammation	Altered Intercellular Communication	Our study suggests that the reduction in synovial inflammation may be due to the decreased production of TNF-alpha and IL-8, and hence the number of neutrophils and other pro-inflammatory leukocytes infiltrating into the inflamed sites.	17996676
Inflammation	Altered Intercellular Communication	De-novo expression of MMP-25 and -26 is associated with periodontal and peri-implant inflammation.	17996844
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Atrial stunning, inflammation and nutritional status after cardioversion from atrial fibrillation.	17996968
Inflammation, Electrocardiogram: myocardial infarction (finding), Atherosclerosis	Altered Intercellular Communication	Inflammation is a key component in the development of atherosclerosis, and myocardial infarction (MI); therefore we investigated the association between an interleukin-6 signal transducer (IL6ST)/gp130 polymorphism, gp130 function and risk of MI.	17997171
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The association of low-grade inflammation, urinary albumin, and insulin resistance with metabolic syndrome in nondiabetic Taiwanese.	17998025
Inflammation, Endothelial dysfunction, Metabolic Syndrome X, Cardiovascular Diseases	Altered Intercellular Communication	Metabolic syndrome, which involves different pathological mechanisms in associated disorders including inflammation, endothelial dysfunction, and insulin resistance, results in the development of cardiovascular diseases.	17998025
Inflammation, No metabolic abnormalities	Altered Intercellular Communication	More metabolic abnormalities were associated with higher risk of inflammation, urinary albumin, and insulin resistance.	17998025
Respiratory physiology, Colonization, Inflammation, Pseudomonas aeruginosa	Altered Intercellular Communication	Independent factors associated with an accelerated decline of lung function were chronic colonization with Pseudomonas aeruginosa (PA) [odds ratio (OR), 30.4; 95% confidence interval (CI), 3.8 to 39.4; p=0.005], more frequent severe exacerbations (OR, 6.9; 95% CI, 2.3 to 10.5; p=0.014), and more systemic inflammation (OR, 3.1; 95% CI, 1.9 to 8.9; p=0.023).	17998359
Inflammation, Bronchiectasis, Exacerbation	Altered Intercellular Communication	Chronic colonization by PA, severe exacerbations, and systemic inflammation are associated with disease progression in non-CF bronchiectasis.	17998359
Aneurysm, Inflammation, Hypertrophy, Unspecified visual loss	Altered Intercellular Communication	MR imaging findings suggested that the visual loss was most likely caused by perianeurysmal inflammation related to the coils used to embolize the aneurysm, enlargement or persistence of the aneurysm despite coiling, or a combination of these mechanisms.	17998416
Inflammation	Altered Intercellular Communication	A significantly higher expression rate of A type 3 antigens in endothelial cells was also observed in diseased skin, suggesting that inflammation might induce A type 3 antigen expression in endothelial cells.	17998569
Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Systemic lupus erythematosus (SLE) is an autoimmune disease with unknown etiology, characterized by the presence of auto-antibodies to various cellular components and chronic inflammation of different organ systems.	17999073
Chronic suppurative inflammation	Altered Intercellular Communication	Histologic examination of tissue biopsies showed amorphous aggregates of eosinophilic granules in a background of chronic suppurative inflammation.	17999585
Lymphoid hyperplasia, Serositis	Altered Intercellular Communication	However in 27 of 49 normal looking appendices in females, findings such as serositis, luminal inflammation, lymphoid hyperplasia, etc.	17999817
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Chronic inflammation has been hypothesized to increase prostate cancer risk.	17999989
Hepatic Encephalopathy, Synaptic cleft, Liver Cirrhosis	Altered Intercellular Communication	The decrease of cerebral A(1)AR binding may further aggravate neurotransmitter imbalance at the synaptic cleft in cirrhosis and hepatic encephalopathy.	18000666
Inflammation	Altered Intercellular Communication	High-density lipoprotein (HDL) could enhance inflammation in atherogenesis when inflammatory response is present, and the activity of paraoxonase and antioxidant in HDL in the elderly is significantly decreased.	18000966
Inflammation	Altered Intercellular Communication	The persistence of chronic inflammation in gastric mucosa and elevated Helicobacter pylori antibodies after successful eradication therapy are common findings in clinical practice.	18001400
Inflammation, Gastritis	Altered Intercellular Communication	The prevalence of chronic gastric inflammation and elevated H. pylori antibodies after successful eradication therapy decreased by time, but still after 5 years, 17 of 51 (33%) subjects had elevated H. pylori antibodies and 14 of 68 (21%) had a mild inactive chronic inflammation in gastric mucosa.	18001400
Inflammation	Altered Intercellular Communication	In patients with and without chronic inflammation in gastric mucosa, elevated H. pylori antibodies were detected in three of 10 (30%) and 14 of 41 (34%), elevated parietal cell antibodies in one of 10 (10%) and six of 41 (15%), low pepsinogen I in one of 10 (10%) and none of 41, and elevated gastrin-17 in three of 10 (30%) and six of 41 (15%), respectively.	18001400
Inflammation	Altered Intercellular Communication	More than 5 years after successful H. pylori eradication therapy, mild persistent chronic inflammation may occur in gastric mucosa in up to one-fifth and elevated H. pylori antibodies even in one-third of patients, although these two are independent phenomena.	18001400
Inflammatory disease of mucous membrane	Altered Intercellular Communication	The presence of MMP-1, -9, -10 and -26 in both PG and IBD ulcers may suggest a similar pathogenesis for cutaneous and mucosal inflammation.	18001410
Airway structure, ARCN1 gene	Altered Intercellular Communication	Patterns of airway inflammation and MMP-12 expression in smokers and ex-smokers with COPD.	18001475
Airway structure, ARCN1 gene	Altered Intercellular Communication	However, the influence of smoking and its cessation on airway inflammation and MMP-12 expression during COPD is still unknown.	18001475
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Lactoferrin in feces reflects the disease activity of UC and is a rational fecal marker of intestinal inflammation for clinical application.	18001547
Schistosomiasis, Hepatic inflammation, Acute Disease	Altered Intercellular Communication	sTNFR-II and sICAM-1 are associated with acute disease and hepatic inflammation in schistosomiasis japonica.	18001742
Hepatitis	Altered Intercellular Communication	The results suggest sTNFRs and sICAM-1 are associated with liver inflammation and disease progression.	18001742
Hepatic inflammation, Acute Disease	Altered Intercellular Communication	Measurement of sTNFR-II and sICAM-1 levels in serum could serve as additional markers for the diagnosis of acute stage disease and the monitoring of hepatic inflammation in human schistosomiasis japonica.	18001742
Communicable Diseases, vascular aneurysm, Inflammation	Altered Intercellular Communication	Patients with primary stricture disease may be at increased risk for vascular aneurysm due to infection and/or inflammation.	18001789
Pain Distress Question, Fever, CTCAE, Fever, Brucellosis, Familial Mediterranean Fever	Altered Intercellular Communication	Familial Mediterranean fever (FMF) is a febrile disease characterized by acute, spontaneously resolving episodes of fever and pain caused by serosal inflammation and associated with mutations in the FMF gene, MEFV.	18004180
Inflammation	Altered Intercellular Communication	Proteases destroy important growth factors and matrix proteins, inflammation is prolonged, and the normal healing process does not take place within the expected time span.	18004538
Migraine Disorders, Neurogenic Inflammation, Depression, CTCAE	Altered Intercellular Communication	Cortical spreading depression and neurogenic inflammation have been hypothesized to be key steps in the development of migraine headache.	18005141
Neurogenic Inflammation, Depression, CTCAE, Cerebral Ischemia	Altered Intercellular Communication	Recent studies have highlighted matrix metalloproteinase-9 (MMP-9) in cortical spreading depression, neurogenic inflammation, and cerebral ischemia.	18005141
Inflammation	Altered Intercellular Communication	The first biopsy of the patient showed chronic dermal inflammation.	18005518
Cessation of life, Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) plays important roles in regulating cell death, immune response, and inflammation.	18005854
Inflammation, Helicobacter pylori, Gastritis, Communicable Diseases, Malignant Neoplasms, Peptic Ulcer	Altered Intercellular Communication	Infection with Helicobacter pylori is linked to inflammation and is the main cause of peptic ulcer, gastritis, and gastric malignancies.	18006930
Inflammation, Metabolic Diseases, Diabetes Mellitus, Atherosclerosis	Altered Intercellular Communication	Metabolic disorders developing in diabetes are associated with impaired endothelial function and the presence of subclinical inflammation, in consequence leading to generalized atherosclerosis.	18018381
Necrosis with inflammation	Altered Intercellular Communication	A biopsy of the nasal mucosa showed acute necrotic inflammation.	18019218
septic, Bronchitis	Altered Intercellular Communication	The present study evaluated apoptosis in the nasal and buccal mucosa of septic patients as an alternative and less invasive approach for studying the cells involved in bronchial inflammation.	18019433
Lipogranuloma, Inflammation	Altered Intercellular Communication	Xanthogranuloma is a rare type of inflammation and very few cases have been reported in the pancreas.	18019685
Inflammation, Chronic Obstructive Airway Disease, Gonadal Steroid Hormones	Altered Intercellular Communication	Sex hormone alterations and systemic inflammation in chronic obstructive pulmonary disease.	18021209
Inflammation, Chronic Obstructive Airway Disease, Gonadal Steroid Hormones	Altered Intercellular Communication	Sex hormone alterations and systemic inflammation in chronic obstructive pulmonary disease.	18021209
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Decreased anabolic hormone levels are described in chronic obstructive pulmonary disease (COPD), leading to important clinical consequences.	18021209
Inflammation	Altered Intercellular Communication	A VAS questionnaire evaluated symptoms of infection/inflammation by both the patient and the periodontologist at suture removal.	18021264
Inflammation, Cardiovascular Diseases, Depression, CTCAE, Ischemia	Altered Intercellular Communication	Depression, inflammation, and incident cardiovascular disease in women with suspected coronary ischemia: the National Heart, Lung, and Blood Institute-sponsored WISE study.	18021871
Inflammation, Depression, CTCAE, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	The purpose of this study was to examine prospectively whether inflammation explains the relationship between depression and cardiovascular disease (CVD).	18021871
Inflammation, Depression, CTCAE, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	It is unclear whether inflammation is a mechanism linking depression to CVD.	18021871
Inflammation, Heart failure, Depression, CTCAE	Altered Intercellular Communication	While it appears to be clear that an inflammatory process occurs in heart failure (HF), it is still to be defined whether inflammation depends to a greater extent on HF etiology, functional class (FC), or the extent of depression of ejection fraction (EF).	18022711
Inflammation, Infiltration, Myositis, CTCAE 5.0	Altered Intercellular Communication	Muscles of myositis patients examined with MRI demonstrate heterogeneous pathology ranging from unaffected muscle groups to severe inflammation, fat infiltration, and eventually, more serious fat replacement.	18022843
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	To investigate the role of local colonic mucosal NK receptor-positive T (NKR(+) T) cells in the regulation of intestinal inflammation, we analyzed the population and function of these cells in ulcerative colitis (UC).	18023089
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Selective reduction in the population of colonic mucosal NKR(+) T cells may contribute to the development of intestinal inflammation in UC.	18023089
Inflammation, Chronic infectious disease	Altered Intercellular Communication	Malakoplakia, typically involving the urinary tract, is an uncommon form of chronic inflammation caused by chronic infections and characterized by accumulation of macrophages.	18023111
Inflammation, Hemorrhage, Neoplasms, Mediastinal Neoplasms, Thymic Cyst	Altered Intercellular Communication	CT should be considered the modality of choice following chest radiography, however, in certain circumstances, such as thymic cyst with hemorrhage or inflammation which mimic solid tumor despite low enhancement, MRI may be better in distinguishing anterior mediastinal tumors.	18023547
Inflammation, Carotid artery occlusion	Altered Intercellular Communication	Multiple technical approaches may be required, depending on the length and location of the lesion and stents, the presence of complete common carotid occlusion, and the degree of surrounding inflammation.	18023558
Inflammation, Hepatitis B	Altered Intercellular Communication	Hepatitis B and C viruses induce chronic inflammation and oxidative stress that could predispose a cell to mutagenesis and proliferation.	18023606
Alzheimers Disease", Inflammation	Altered Intercellular Communication	Alzheimer's disease involves Abeta accumulation, oxidative damage and inflammation and there is currently no clinically accepted treatment to stop its progression.	18023978
Intraocular inflammation	Altered Intercellular Communication	Most of the patients had bilateral and recurrent intraocular inflammation.	18024808
Infection caused by Helicobacter pylori, Esophageal, Metaplasia, Gastritis, Atrophic, Adenocarcinoma	Altered Intercellular Communication	Relationship between Helicobacter pylori infection and gastric atrophy and the stages of the oesophageal inflammation, metaplasia, adenocarcinoma sequence: results from the FINBAR case-control study.	18025067
Infection caused by Helicobacter pylori, Esophageal, Metaplasia, Gastritis, Atrophic, Adenocarcinoma	Altered Intercellular Communication	The relationship between all stages of the oesophageal inflammation, metaplasia, adenocarcinoma sequence and H pylori infection and gastric atrophy was explored.	18025067
Inflammation, Atherosclerosis	Altered Intercellular Communication	Socioeconomic position, race/ethnicity, and inflammation in the multi-ethnic study of atherosclerosis.	18025402
Inflammation	Altered Intercellular Communication	Inflammation could be an important mediating mechanism linking socioeconomic position to cardiovascular risk.	18025402
Inflammation	Altered Intercellular Communication	Both household income and education are associated with inflammation, but associations vary across race/ethnic groups.	18025402
Inflammation	Altered Intercellular Communication	Under the administration of nonsteroidal anti-inflammatory drug, the inflammation lessened.	18025768
Inflammation	Altered Intercellular Communication	Early clinical results of open and arthroscopic synovectomy in knee inflammation.	18026071
Inflammation	Altered Intercellular Communication	The diagnosis was made by colon biopsies, which showed chronic inflammation with many histiocytes containing Michaelis-Gutmann bodies.	18026580
Alzheimers Disease", Data types - Address, Frontotemporal dementia	Altered Intercellular Communication	Information is sparse on neurotransmitter deficiencies in frontotemporal dementia (FTD), in particular with reference to distinct histological subgroups and Alzheimer's disease (AD).	18026720
Inflammation, Tissue Adhesions	Altered Intercellular Communication	A total of 71% of patients showed positive surgical findings; 55.5% of these showed variations in the position of the appendix with mild inflammation and reactive pericaecal lymph nodes, 7.5% had a macroscopic inflammation with adhesions and 37% had a mild inflammation.	18026737
Inflammation, Tissue Adhesions, Infection	Altered Intercellular Communication	Twenty-nine percent of patients had a normal appendix without adhesions, inflammations or infections.	18026737
Inflammation	Altered Intercellular Communication	A histological analysis of macroscopically inflamed synovia revealed an unspecific inflammation reaction.	18026967
Renal Insufficiency, Inflammation, Liver Dysfunction, Diabetes Mellitus	Altered Intercellular Communication	Recognition of potential Lp(a) variability associated with common diseases, such as diabetes, chronic renal dysfunction, impaired liver function and acute/chronic inflammation, is important to optimize the clinical usefulness of this measurement.	18027069
neutrophilic, Inflammation	Altered Intercellular Communication	Cell differentials, markers of neutrophilic and eosinophilic inflammation, respiratory membrane permeability and size-selective permeation were assessed.	18027159
Retinal Pigments, Complication Aspects, Chemosis of conjunctiva, Inflammatory abnormality of the eye, Injury of lens, Corneal Abrasions, Sudden Visual Loss	Altered Intercellular Communication	The ocular complications included corneal abrasion (n = 2), chemosis (n = 2), lens injury (n = 1), ocular inflammation (n = 2), retinal pigment epithelial tear (n = 1) and acute vision loss (n = 1).	18028234
Inflammation	Altered Intercellular Communication	After eradication, a chronic inflammation remains in some patients, but a follow-up study with a comprehensive cytokine profile in has not previously been published.	18028289
Inflammation	Altered Intercellular Communication	However, after eradication a chronic low-grade inflammation was seen with reduced Th1, prolonged Th2 and disappearance of the T-regulatory response.	18028289
Airway structure, Asthma	Altered Intercellular Communication	Fractional exhaled nitric oxide (FE(NO)) is a marker for airway inflammation in asthma.	18029165
Inflammation, Shock, Hemorrhagic	Altered Intercellular Communication	Relationships between markers of inflammation, severity of injury, and clinical outcomes in hemorrhagic shock.	18029320
Inflammation, Traumatic injury	Altered Intercellular Communication	In the THS group, no significant differences were noted between markers of inflammation and trauma scores of patients who died and those who survived.	18029320
Multiple Organ Failure, Inflammation, Sepsis, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	The investigators concluded that although the levels of markers of inflammation increased in THS patients, they were inadequate for predicting mortality and the development of complications such as acute respiratory distress syndrome, multiple organ failure, and sepsis.	18029320
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Inflammation may contribute to progression of knee osteoarthritis (OA).	18029383
Inflammation, Weight decreased	Altered Intercellular Communication	This indicates that 1.1 g/d EPA+DHA supplied for 6 wk, in contrast to approximately 10 kg weight loss, does not improve markers of endothelial function and inflammation.	18029476
Communicable Diseases, Malignant Neoplasms, Transmissible canine venereal tumor	Altered Intercellular Communication	FDG PET/CT, an established imaging modality for staging and restaging workup of malignancies, also demonstrates increased uptake in infectious or inflammatory conditions, including both infectious and noninfectious granulomatous processes.	18030049
Inflammatory abnormality of the eye	Altered Intercellular Communication	However, the expression of VAP-1 in the eye and its contribution to ocular inflammation are unknown.	18032635
Inflammatory abnormality of the eye, EIU, Uveitis	Altered Intercellular Communication	Here, we investigated the role of VAP-1 in an established model of ocular inflammation, the endotoxin-induced uveitis (EIU), using a novel and specific inhibitor.	18032635
Inflammation	Altered Intercellular Communication	Our data suggest an important role for VAP-1 in the recruitment of leukocytes to the immune-privileged ocular tissues during acute inflammation.	18032635
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation has recently proven to be associated with the pathogenesis of atherosclerosis and inflammatory genes are good candidates for the risk of developing atherosclerosis.	18034324
Inflammation, Inflammatory disorder	Altered Intercellular Communication	In postoperative inflammatory diseases of the anterior segment of the eye the cause of the inflammation on the one hand and symptoms on the other hand have to be treated.	18034397
Airway structure, Communicable Diseases	Altered Intercellular Communication	Modulation of TLR4 in respiratory epithelium may have important implications for airway inflammation and infection in response to inhaled pathogens.	18034897
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Effect of ongoing inflammation in rheumatoid arthritis on P-wave dispersion.	18034993
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	It has been emphasized recently that there is a strong association between atrial fibrillation and inflammation.	18034993
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	P-wave dispersion has been encountered as a risk factor for atrial fibrillation and the effect of inflammation on P-wave dispersion has not been studied thoroughly.	18034993
Refractory anemias, Inflammation	Altered Intercellular Communication	The findings of this study suggest that RA may be associated with increases in P-wave dispersion and maximum P-wave duration, and that this association may result from ongoing inflammation.	18034993
Inflammation, Sore to touch, Edema	Altered Intercellular Communication	Otic inflammation, tenderness, edema, and discharge were clinically assessed on days 3, 8, and 18 of the studies.	18035194
Inflammation	Altered Intercellular Communication	To this end, PD-associated inflammation was modeled by stimulation of microglia with aggregated and nitrated alpha-syn.	18036154
prostatitis	Altered Intercellular Communication	The relationship between prostate inflammation and lower urinary tract symptoms: examination of baseline data from the REDUCE trial.	18036719
Inflammation	Altered Intercellular Communication	Both age and average chronic inflammation were significant in the linear regression after adjustment for other covariates; for both variables, more severe inflammation was associated with higher IPSS scores.	18036719
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	In the REDUCE population, there is evidence of a relationship between the degree of LUTS and the degree of chronic inflammation.	18036719
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	Study entry criteria that selected older men and decreased enrolment of men with a greater degree of inflammation and LUTS may have limited the strength of this relationship.	18036719
Lower Urinary Tract Symptoms, prostatitis	Altered Intercellular Communication	The impact of baseline prostate inflammation on progression of LUTS and/or associated complications will be determined during 4-yr longitudinal follow-up.	18036719
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	The role of chronic inflammation in the pathogenesis of Alzheimer's disease (AD) has been implied in a plethora of studies.	18037502
Inflammation	Altered Intercellular Communication	There was active inflammation in the polyps in nearly all cases (n = 24) and most showed changes in adjacent non-hyperplastic bowel mucosa such as focal basal cryptitis and apoptosis of crypt epithelium (16 patients).	18037663
Inflammation, Hyperplastic Polyp	Altered Intercellular Communication	Inflammation in conjunction with the increased epithelial proliferation characteristics of hyperplastic polyps could be the mechanism for the MEG formation.	18037663
ARCN1 gene, Inflammation	Altered Intercellular Communication	Whereas smoking cessation reduces respiratory symptoms and lung function decline in COPD, inflammation persists.	18039368
Inflammation, Necrosis	Altered Intercellular Communication	The lesion contained abundant necrotic tissue, the borders showed evident signs of inflammation, and there was abundant prurulent exudate.	18039441
Inflammation, Periodontitis, Cardiovascular Diseases, Endothelial dysfunction, Hypertensive (finding)	Altered Intercellular Communication	These findings suggest that periodontitis is associated with endothelial dysfunction in subjects without cardiovascular risk factors, as well as hypertensive patients, through a decrease in NO bioavailability and that systemic inflammation may be, at least in part, a cause of endothelial dysfunction, leading to cardiovascular diseases.	18039979
Inflammation, Atherosclerosis	Altered Intercellular Communication	Osteogenesis associates with inflammation in early-stage atherosclerosis evaluated by molecular imaging in vivo.	18040026
Inflammation, atherosclerotic	Altered Intercellular Communication	We tested the hypothesis that inflammation promotes osteogenesis in atherosclerotic plaques using in vivo molecular imaging in apolipoprotein E-/- mice (20 to 30 weeks old, n=35).	18040026
Inflammation, Atherosclerosis	Altered Intercellular Communication	Altered plasma versus vascular biopterins in human atherosclerosis reveal relationships between endothelial nitric oxide synthase coupling, endothelial function, and inflammation.	18040031
Atherogenesis, Inflammation, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	A panel of multiple markers associated with chronic systemic inflammation and the risk of atherogenesis is detectable in asthma and chronic obstructive pulmonary disease.	18041101
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Lung diseases	Altered Intercellular Communication	Asthma and chronic obstructive pulmonary disease (COPD) are both lung diseases involving chronic inflammation of the airway.	18041101
Inflammation, Inflammatory airway disease	Altered Intercellular Communication	We wanted to know whether risk markers for atherogenesis corresponding to sequence of events of chronic inflammation were also detectable in the airway inflammatory diseases.	18041101
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	Elevation of almost all markers involving inflammation of the endothelial cells in the coronary artery were detectable in asthma and COPD involving the inflammation of the epithelial cell lining of the airway.	18041101
Vasculitis, CTCAE, Urticaria	Altered Intercellular Communication	Over the course of 8 weeks, the pathology progressed from an extensive red papular urticaria to vasculitis with peri-vascular inflammation and ulceration of the skin on the feet, ankles and lower limbs.	18041296
Inflammation	Altered Intercellular Communication	Histologic findings include nonspecific atrophy of the epidermis and chronic inflammation.	18042336
Inflammation, Rheumatoid Arthritis, Necrosis	Altered Intercellular Communication	Responsiveness to anti-tumour necrosis factor alpha therapy is related to pre-treatment tissue inflammation levels in rheumatoid arthritis patients.	18042642
Inflammation	Altered Intercellular Communication	We identified several biological processes, related to inflammation, which were up-regulated in patients who responded to therapy, compared to those who did not show clinical improvement.	18042642
Colorectal Carcinoma	Altered Intercellular Communication	Inflammation-based prognostic score is a novel predictor of postoperative outcome in patients with colorectal cancer.	18043109
Intracorneal Route of Drug Administration, Keratitis	Altered Intercellular Communication	A retained intracorneal bee stinger may result in long-term corneal inflammation, which may not be controlled adequately with topical steroids.	18043193
Keratitis, Hypopyon	Altered Intercellular Communication	Corneal inflammation and hypopyon resolved, leaving a minimal residual leucoma.	18043195
Heart Diseases, Inflammation	Altered Intercellular Communication	Anthropometric data, signs of arterial, cardiac and renal disease, systemic inflammation and health economics formed the major categories of the empiric clinical profile that described an individual patient's disease activity.	18043731
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The aetiology of pathological findings of intra-articular inflammation and fibrosis is not known.	18043780
Inflammation, Bacterial Infections	Altered Intercellular Communication	Bacterial infections with local inflammation or hematogenous spreading may occur after joint punctures and intra- or periarticular injections.	18043902
Inflammation, Angina, Unstable	Altered Intercellular Communication	Recent studies have suggested important roles of inflammation in the pathophysiology of unstable angina (UA).	18043994
Prostate carcinoma, prostatitis	Altered Intercellular Communication	(Understanding the role of prostate inflammation resolution to prostate cancer evolution).	18044088
Airway structure	Altered Intercellular Communication	Randomized placebo controlled assessment of airway inflammation due to racemic albuterol and levalbuterol via exhaled nitric oxide testing.	18044102
Inflammation, Disease	Altered Intercellular Communication	Tolosa Hunt syndrome is a rare disorder caused by nonspecific inflammation in the cavernous sinus/superior orbital fissure and/or orbital apex.	18044475
Cataract, Intraocular inflammation, Choroidal Neovascularization, Macular Edema, Cystoid	Altered Intercellular Communication	Demographic information, visual acuity at presentation, and presence of intraocular inflammation, choroidal neovascularization (CNV), and structural complications of intraocular inflammation (including cataract, cystoid macular edema [CME], and epiretinal membrane [ERM]) were compared for the two groups.	18046221
Intraocular inflammation, Visual Impairment	Altered Intercellular Communication	Patients with PIC had a higher frequency of CNV at presentation but lower frequencies of structural complications from intraocular inflammation and a lower frequency of visual impairment at presentation.	18046221
Inflammation, Migraine Disorders	Altered Intercellular Communication	Inflammation is thought to play a role in the pathophysiology of migraine and there is conflicting evidence regarding the effect of corticosteroids on reducing early recurrences.	18047499
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Imbalanced Th1/Th2 may play a role in the sustained inflammation of IBD.	18048021
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	We conclude that a heightened, perhaps persistent, activational state of IL-12/Stat4, and/or IL-23/Stat4 signaling may be present in active Chinese UC patients, and possibly involved in chronic inflammation in UC.	18048021
Inflammation, Ischemic stroke	Altered Intercellular Communication	Early signaling of inflammation in acute ischemic stroke: clinical and rheological implications.	18048088
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Rosiglitazone improves endothelial function and inflammation but not asymmetric dimethylarginine or oxidative stress in patients with type 2 diabetes mellitus.	18048467
Inflammation, Anemia, Depression, CTCAE	Altered Intercellular Communication	Mental status, metabolic/muscular status, systemic inflammation, and anemia were assessed by Beck Depression Inventory, bioelectrical impedance analysis, handgrip strength, high-sensitivity C-reactive protein/fibrinogen, and hemoglobin, respectively.	18048807
ARCN1 gene, Inflammation, Left ventricular systolic dysfunction	Altered Intercellular Communication	Higher values of systemic inflammation and left cardiac dysfunction are associated with reduced physical activity in patients with COPD.	18048807
Nontuberculous Mycobacteria Measurement, Malnutrition, Pneumonitis, Pneumonia	Altered Intercellular Communication	She suffered from nontuberculous mycobacterium (NTM), and her lung inflammation deteriorated due to aspiration pneumonia and malnutrition.	18049013
Inflammation	Altered Intercellular Communication	On impression cytology examination, there was a significant increase in inflammation, presence of a honeycomb pattern, plasma cells, and mucus strands in the upper tarsal conjunctiva of the specimens.	18050126
Papilledema, Vitreous inflammatory cells	Altered Intercellular Communication	A 65-year-old woman with visual acuity (VA) 20/40, mild vitreous inflammation, optic disc edema, and white deep retinal round lesions in the right eye underwent fluorescein angiography, indocyanine green angiography, and optical coherence tomography.	18050132
Orchitis, Joint structure of shoulder region	Altered Intercellular Communication	US shoulder examination performed at the end of followup demonstrated a parallel reduction of glenohumeral and periarticular inflammation.	18050171
Sepsis, Inflammation, Septic Shock	Altered Intercellular Communication	The following symptoms of inflammation were observed: syndrome of systemic inflammatory reaction--in 13 (5.37%) patients, sepsis--in 190 (78.51%), severe sepsis in 16 (6.61%), septic shock--in 23 (9.5%) patients.	18050643
Inflammation, diabetic	Altered Intercellular Communication	To avoid an increase in insulin resistance, it seems important to attend to radically non-vital teeth as well as any other dental inflammation in diabetic patients.	18052712
ARCN1 gene, Airway structure, Chronic Obstructive Airway Disease, Asthma, IL13 gene	Altered Intercellular Communication	In contrast to the epidemiological and clinical association between allergic rhinitis and asthma, upper airway inflammation is less characterized in patients with nonatopic asthma and virtually unexplored in chronic obstructive pulmonary disease (COPD).	18053011
ARCN1 gene, Allergic, Nasal inflammation, Intrinsic asthma	Altered Intercellular Communication	Patients with allergic and nonallergic asthma and COPD show increased nasal symptoms and more nasal inflammation.	18053011
Gastrointestinal inflammation	Altered Intercellular Communication	Down-regulation of the monocarboxylate transporter 1 is involved in butyrate deficiency during intestinal inflammation.	18054563
Colitis	Altered Intercellular Communication	We aimed to investigate the role of MCT1 in butyrate oxidation deficiency during colonic inflammation.	18054563
Gastrointestinal inflammation	Altered Intercellular Communication	The data suggest that butyrate oxidation deficiency in intestinal inflammation is a consequence of reduction in MCT1-mediated butyrate uptake.	18054563
Inflammation, Endothelial dysfunction, Hypothyroidism	Altered Intercellular Communication	Recent studies suggest that there is evidence of inflammation and endothelial dysfunction in hypothyroidism.	18055424
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	The present study demonstrates that CT-1 promotes monocyte adhesion and migration by stimulating ICAM-1 and MCP-1 through mechanisms that involve ERK1/2 MAP kinase, p38 MAP kinase, phosphatidylinositol 3-kinase, and NF-kappaB pathways and suggests that CT-1 plays an important role in the pathophysiology of vascular inflammation and atherosclerosis.	18055523
Inflammation, Rhodococcus erythropolis, Genus Erwinia	Altered Intercellular Communication	Atypical ocular surface bacteria including Rhodococcus erythropolis, Klebsiella oxytoca, and Erwinia sp., were identified in cases of overt inflammation and, surprisingly, on the normal ocular surface.	18055811
Communicable Diseases, Inflammation	Altered Intercellular Communication	It remains unknown whether their presence is associated with inflammation and reduced goblet cell density or whether they adversely affect the ocular surface predisposing it to abnormal microbial colonization.	18055811
Diabetes Mellitus, Non-Insulin-Dependent, Excessive glucagon secretion	Altered Intercellular Communication	This suggests that the defects in GLP-1 concentrations previously described in patients with long-standing type 2 diabetes are likely secondary to other hormonal and metabolic alterations, such as hyperglucagonemia.	18057091
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Measurements of pulmonary biomarkers can be used to monitor airway inflammation in chronic obstructive pulmonary disease (COPD), but the variability of sampled biomarkers and their inter-relationships are poorly understood.	18057097
Inflammation, Edema	Altered Intercellular Communication	Inferior vena cava diameter, blood volume monitoring, plasma volume markers, and inflammation markers were not determinants of edema.	18057304
Hormone abnormality, Chronic disease	Altered Intercellular Communication	The analysis comprised 41 healthy short children (25 boys); aged 5.2-16.3 years, in whom hormonal disorders and chronic diseases had been excluded.	18058719
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Leptin may play an important role in colorectal cancer because of its role in energy balance, insulin and inflammation.	18059035
PDC wt Allele, Hypothyroidism	Altered Intercellular Communication	Hormonal studies showed that the patient had GH deficiency and secondary hypothyroidism, consistent with CPHD.	18059085
Inflammation, Canalicular cholestasis	Altered Intercellular Communication	The lobules showed canalicular cholestasis and mild to moderate inflammation.	18059233
Hepatitis A, Cholestanes, Chronic lymphocytic inflammation	Altered Intercellular Communication	In conclusion, early after acute hepatitis C viral infection, biopsies can have a cholestatic pattern whereas later biopsies tend to show mild nonspecific portal and lobular lymphocytic inflammation.	18059233
Myositis	Altered Intercellular Communication	Some degree of muscle inflammation was found at histological analysis.	18060361
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	The inhibitory effects of atorvastatin on inflammation in ACS may be due to its beneficial effects on Treg and restoration of immune homeostasis.	18060626
Inflammation, Glaucoma, CTCAE, Perforation (observation), Corneal Diseases	Altered Intercellular Communication	Multivariate analysis revealed 9 predictors for graft failure: recipient gender, age, graft size, graft endothelial status, primary corneal disease, glaucoma, inflammation, perforation, and corneal vascularization.	18061267
Orthodontic, Inflammation, Osteopenia	Altered Intercellular Communication	While orthodontic treatment can realign such teeth with reduced periodontal support, esthetics may be compromised by gingival recession due to preexisting bone loss and resolution of inflammation after periodontal treatment.	18061735
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Malacoplakia is a relatively rare form of chronic granulomatous inflammation.	18062216
Acute inflammation of orbit, Scleritis	Altered Intercellular Communication	Posterior scleritis should be considered in the differential diagnosis of acute orbital inflammation in children younger than 1 year.	18062497
Inflammation	Altered Intercellular Communication	Serum fatty acid composition and indices of stearoyl-CoA desaturase activity are associated with systemic inflammation: longitudinal analyses in middle-aged men.	18062827
Inflammatory abnormality of the eye	Altered Intercellular Communication	LE/T satisfied the condition of non-inferiority to DM/T in decreasing the signs and symptoms of ocular inflammation associated with blepharokeratoconjunctivitis.	18062846
Inflammation	Altered Intercellular Communication	Smoking, the prothrombotic aspect of systemic inflammation, or a genetic predisposition may contribute to the risk.	18063423
Inflammation, Malignant Neoplasm of Lung - Multiple Primary Sites, Non-Neoplastic Disorder, Hemangioma	Altered Intercellular Communication	Pathologic examination revealed seven primary lung cancers, 11 metastases, one hemangioma, 19 definite non-neoplastic pathologies, two nonspecific chronic inflammation, and three metallic foreign bodies.	18063512
Intraocular inflammation	Altered Intercellular Communication	One eye evidenced severe intraocular inflammation after IVBI and a subsequent development of new RAP, which was controlled with vitrectomy and repeat IVBI.	18063885
Inflammation, Squamous metaplasia	Altered Intercellular Communication	The histopathological examination of the dry eye conjunctival samples evidenced the following alterations: loss of calyciforme cells, squamous metaplasia of the epithelium, subepithelial inflammation.	18064961
Inflammation	Altered Intercellular Communication	The histological analysis confirms the implication of inflammation in the pathogenesis of the disease.	18064961
Tears body substance, Inflammation	Altered Intercellular Communication	The time of onset of the inflammation cannot be established, it may be initial or it may occur with the quantitative decrease of tears or with eye surface alterations.	18064961
Communicable Diseases, Acute Bacterial Prostatitis, Inflammation	Altered Intercellular Communication	The Korean Association of Urogenital Tract Infection and Inflammation (KAUTII) conducted a multicentre, retrospective analysis of acute bacterial prostatitis (ABP) to document clinical features, management, microbiology and the course of disease.	18065208
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is associated with increased whole body protein breakdown and low-grade systemic inflammation.	18067517
Inflammation, Metallosis	Altered Intercellular Communication	Other findings included a perivascular lymphocytic infiltrate (n=5), features of active inflammation (n=4), and metallosis (n=1).	18068790
Ischemia, Inflammation, Thrombophilia	Altered Intercellular Communication	Warm ischemia provokes inflammation and regional hypercoagulability within the heart during off-pump coronary artery bypass: a possible target for serine protease inhibition.	18068996
Coronary Occlusion, Inflammation, Thrombosis, Coronary Arteriosclerosis	Altered Intercellular Communication	Strong correlations between myocardial ischemia and the transcardiac gradients of markers for inflammation and thrombosis suggest that even brief episodes of coronary occlusion in the beating heart may have pathophysiologic consequences.	18068996
Pain Distress Question, Discogram, Inflammation	Altered Intercellular Communication	The purpose of this study was to correlate concordant pain on discography with MRI grade and biochemical markers of inflammation in a clinical setting.	18069067
Orbital Pseudotumor	Altered Intercellular Communication	[Significance of serum antibodies ANCA, ASCA, ABBA in diagnostics of idiopathic intestinal inflammations].	18069213
Inflammation, Sarcoidosis, Fibrosis Assessment, Granulomatous disorder, Berylliosis, cannabidiol	Altered Intercellular Communication	Sarcoidosis and chronic beryllium disease (CBD) are granulomatous disorders which can lead to development of chronic inflammation and fibrosis.	18069416
Inflammation	Altered Intercellular Communication	Telomere attrition is associated with inflammation, low fetuin-A levels and high mortality in prevalent haemodialysis patients.	18070000
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Age and male gender seem to be important contributors to reduced telomere length in CKD patients, possibly via persistent inflammation.	18070000
Inflammation, Ulcer	Altered Intercellular Communication	Venous ulcers are characterized by excessive inflammation and raised levels of proinflammatory cytokines.	18070128
Airway structure, Respiratory Hypersensitivity, Airway Obstruction, Chronic disease	Altered Intercellular Communication	Asthma is a chronic disease defined by airway inflammation, increased airway hyperresponsiveness and episodes of airway obstruction.	18070153
Airway structure, Asthma	Altered Intercellular Communication	By inducing a pro-inflammatory cytokine milieu, stress might enhance airway inflammation in bronchial asthma.	18070153
Inflammation, Transitional cell carcinoma of ureter, Neoplasms	Altered Intercellular Communication	Three patients had tumours of the prostatic urethra, two of which had proliferating focal inflammation and one a low-grade, superficial urothelial cancer.	18070169
Deficit, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	* Deficit in central cholinergic neurotransmission is a consistent change associated with Alzheimer's disease (AD).	18070217
Inflammation	Altered Intercellular Communication	The current theories of chronic inflammation leading to autoimmune response with destruction and loss of the inhibitory myenteric ganglion cells enlighten its pathogenesis in a limited way only.	18070236
Impaired health	Altered Intercellular Communication	The associated reduced NOS release might underlie the profound ICC impairment and could possibly be responsible for the lack of LES relaxation, because of missing inhibitory neurotransmission.	18070236
Inflammation, Hypoadiponectinemia, Obesity	Altered Intercellular Communication	To investigate the involvement of hypoadiponectinemia and inflammation in coupling obesity to insulin resistance in melanocortin-3 receptor and melanocortin-4 receptor knockout (KO) mice (Mc3/4rKO).	18070757
Inflammation, Aortic Arch Syndromes	Altered Intercellular Communication	Detection of inflammation in patients with acute aortic syndrome: comparison of FDG-PET/CT imaging and serological markers of inflammation.	18070949
Inflammation	Altered Intercellular Communication	Vessel wall inflammation was found in one-third of the patients with AAS and this patient group seems to have a high risk for disease progression.	18070949
Inflammation, Asthma	Altered Intercellular Communication	Some studies of severe asthma suggest that persistence or alteration in the pattern of inflammation may be associated with the severity of the disease.	18071017
Orbital Pseudotumor	Altered Intercellular Communication	Intraorbital injection of triamcinolone acetonide in patients with idiopathic orbital inflammation.	18071116
Orbital Pseudotumor	Altered Intercellular Communication	This prospective, noncomparative, interventional case series included patients with clinically, radiologically, and histologically confirmed idiopathic orbital inflammation with an anterior orbital mass.	18071116
Orbital Pseudotumor	Altered Intercellular Communication	Intraorbital injection of a corticosteroid is an effective treatment for idiopathic orbital inflammation and may be considered first-line treatment in selected patients.	18071116
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	This case indicates that immunological factors, inflammation or vasculitis might have possibly been associated with the development of either an obstruction or stenosis of the intracranial internal carotid arteries.	18072414
Granuloma, Necrosis, Tuberculosis, Granulomatous inflammation	Altered Intercellular Communication	Diagnosis is based on histological biopsy which shows granulomas without necrosis, while other causes of granulomatous inflammation, especially tuberculosis, have been excluded.	18074720
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Within a six month period, serum ALT levels dropped into the normal range in 23/76 (30.3%) patients and serum ALT in the 6th month correlated significantly with the severity of steatosis, inflammation and fibrosis in initial biopsy (p = 0.023, 0.035, 0.011, respectively).	18074737
Inflammation, Fibrosis Assessment, Diabetes Mellitus	Altered Intercellular Communication	Overt diabetes is predictive of advanced fibrosis and inflammation.	18074737
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver biopsy revealed portal inflammation, hepatocellular and canalicular cholestasis, porto-portal and portocentral bridging fibrosis, and a tendency to form nodules.	18074740
Inflammation, Dysplasia, Metaplasia	Altered Intercellular Communication	As regards histology: 24 patients showed inflammation, while 2 patients with alterations in traditional endoscopy and with MB showed metaplasia and high grade dysplasia.	18074937
Intestinal metaplasia, Inflammation, Dysplasia	Altered Intercellular Communication	In 4/30 (13.3%) patients MB guided biopsies showed significant lesions (3 intestinal metaplasia, 1 low grade dysplasia) while random biopsies showed only inflammation.	18074937
Inflammation	Altered Intercellular Communication	The significant decrease of fetuin-A levels after a single HD session is consistent with the hypothesis of HD-induced inflammation; activated acute phase response and fetuin-A deficiency might account for increased cardiovascular risk and accelerated atherogenesis in dialysis patients.	18076347
Inflammation, Endothelial dysfunction, Intermittent Claudication	Altered Intercellular Communication	To evaluate the relationship between C-Reactive Protein (hsCRP), a serum marker of inflammation, and endothelial dysfunction in patients with intermittent claudication.	18077193
Inflammation	Altered Intercellular Communication	Visual MRI scores for mural inflammation were correlated with clinical and laboratory findings.	18077491
Inflammation, Disease remission	Altered Intercellular Communication	Of the two patients with active disease, one had persisting mural inflammation in MRI indicative of relapsing disease.	18077491
Inflammation, Fever, Temporal Arteritis, Claudication (finding)	Altered Intercellular Communication	Duplex ultrasound of the temporal, subclavian, axillary and proximal brachial arteries was performed in all patients with suspected temporal arteritis, PMR, arm claudication, unclear inflammation or pyrexia of unknown origin (PUO).	18077499
Inflammation, Pyrexia of unknown origin (excl puerperal), Temporal Arteritis, Claudication (finding)	Altered Intercellular Communication	Performing axillary artery ultrasound in all patients with suspected temporal arteritis, PMR, arm claudication, unclear inflammation or PUO increases the diagnostic yield for LV-GCA.	18077499
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Inflammation plays a key role in the pathogenesis of an AAA (abdominal aortic aneurysm); however, the nature of the inflammatory factors and cellular response(s) involved in AAA growth is controversial.	18078385
APP gene, Autistic behavior	Altered Intercellular Communication	In conclusion, our findings demonstrate that an AAA is a general inflammatory condition which is characterized by enhanced expression and activation of pro-inflammatory transcription factors, accompanied by IL-6 and IL-8 hyperexpression and exaggerated downstream cellular responses, which together clearly distinguish an AAA from ASD.	18078385
Communicable Diseases, Inflammation, Kidney Failure, Collagen Diseases	Altered Intercellular Communication	ESR as a measure inflammation in systemic rheumatic disease may be limited in settings of infection, renal insufficiency, and low albumin.	18078625
Renal Insufficiency, Inflammation, Atherosclerosis	Altered Intercellular Communication	The levels of high-sensitivity C-reactive protein (HSCRP), a marker of inflammation and atherosclerosis, elevate with increasing renal dysfunction.	18078860
Inflammation, Hemorrhagic	Altered Intercellular Communication	Ill-defined centrilobular nodules represented peribronchiolar inflammation or the deposition of hemorrhagic materials.	18079227
Airway structure, Inflammation, Exacerbation	Altered Intercellular Communication	To determine if (1) systemic and airway inflammation is distinct in new bacterial strain exacerbations and (2) clinical severity and resolution of exacerbations is related to airway and systemic inflammation.	18079493
Inflammation, Exacerbation	Altered Intercellular Communication	Neutrophilic airway inflammation and systemic inflammation are more intense with well-defined bacterial exacerbations than with nonbacterial exacerbations.	18079493
Hypersensitivity, allergic inflammation	Altered Intercellular Communication	We conclude that innate immunity plays a role in late phases of type IV hypersensitivity reactions and may be responding to self-lipids released during allergic inflammation.	18079745
Inflammatory Bowel Diseases, malignant disease	Altered Intercellular Communication	Closure of the temporary diverting ileostomy in patients with inflammatory bowel disease or any other inflammatory conditions within the peritoneal cavity are at the increased risk of complications than in those with malignant diseases or precancerous conditions.	18080690
Inflammation, Necrosis	Altered Intercellular Communication	Mean Knodell inflammation (I + II + III) and necrosis (IV) scores at baseline vs. year 2 were compared.	18081733
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Among both groups, the mean change was -3.4 for inflammation and -0.36 for fibrosis.	18081733
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Overall, 73% (95% CI: 67-79) of patients experienced reduced inflammation and 28% (95% CI: 22-34) had reduced fibrosis.	18081733
Hypernatremia	Altered Intercellular Communication	B-type natriuretic peptide (BNP) is a cardiac neurohormone secreted from the cardiac ventricles in response to pressure overload.	18081799
Interstitial Cystitis, Inflammation	Altered Intercellular Communication	Findings strongly suggest abnormal differentiation in the interstitial cystitis urothelium with a loss of barrier function markers and altered differentiation markers being independent and occurring independently of inflammation.	18082196
vascular inflammations, Heart failure	Altered Intercellular Communication	Pentraxin 3, a new marker for vascular inflammation, predicts adverse clinical outcomes in patients with heart failure.	18082493
Inflammation, Postoperative infection	Altered Intercellular Communication	Her initial clinical presentation suggested postoperative infection, but the inflammation continued to progress despite antimicrobial therapy.	18083594
Inflammation, Scleritis, Strabismus	Altered Intercellular Communication	We report an unusual case of necrotizing scleritis with inflammation that occurred after strabismus surgery.	18083594
Inflammation, AHSG protein, human, Vascular calcification	Altered Intercellular Communication	Fetuin-A, a circulating calcium-regulatory glycoprotein that inhibits vascular calcification, is associated with inflammation and outcome in dialysis patients.	18085392
Inflammation, Malnutrition, Heart failure	Altered Intercellular Communication	These data suggest that a low fetuin-A level is a useful predictor of malnutrition and inflammation, as well as being a useful predictor of the cardiac failure caused by an increased ventricular load in hemodialysis patients.	18085392
Inflammation, IGA Glomerulonephritis, Tonsillitis	Altered Intercellular Communication	This case suggests that an inflammation such as tonsillitis may be associated not only with the activity of IgA nephropathy but also with the production of MPO-ANCA.	18085396
Inflammation, Cysticercus	Altered Intercellular Communication	Two cysts of cysticercus cellulosae were seen after control of inflammation.	18085491
Inflammation	Altered Intercellular Communication	Exhaled nitric oxide for monitoring childhood asthma inflammation compared to sputum analysis, serum interleukins and pulmonary function.	18085692
Inflammation, Thrombosis, Congestive heart failure	Altered Intercellular Communication	The immune modulator pair CD40-CD40L has been proposed to be an important link between inflammation and thrombosis and may be important in the pathophysiology of CHF.	18086125
Inflammation, Primary malignant neoplasm, Malignant Neoplasms	Altered Intercellular Communication	These results show the ability of leukocyte telomere length to predict the risk of future cancer and suggest that it might also have predictive value in other cancers arising in a setting of chronic inflammation.	18086770
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The Mediterranean diet is protective against cardiovascular disease; a proposed mechanism is through a reduction in systemic inflammation.	18086924
Inflammation	Altered Intercellular Communication	Shared environmental and genetic factors are unlikely to play a major role in the association between adherence to the Mediterranean diet and systemic inflammation.	18086924
Inflammation	Altered Intercellular Communication	These results support the hypothesis that reduced inflammation is an important mechanism linking Mediterranean diet to reduced cardiovascular risk.	18086924
Necrotizing granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	Sarcoidosis is a systemic disease characterized by chronic granulomatous inflammation.	18087126
Neoplasms	Altered Intercellular Communication	Our data suggest that alterations in p16(INK4a), mainly hypermethylation, may be linked to tumor growth but not tumor development, while alterations in p14(ARF) may contribute to the induction of chronic inflammation-related PTCs.	18087199
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	These results emphasize the role of humoral autoimmunity as a mediator of inflammation and coronary atherogenesis.	18088236
Chronic inflammation	Altered Intercellular Communication	We sought to evaluate influences of oxidative stress (OS) on rHuEPO requirements in hemodialysis patients without chronic inflammation.	18089316
Inflammation, Helicobacter-associated gastritis	Altered Intercellular Communication	Detection of Helicobacter pylori gastritis by PCR: correlation with inflammation scores and immunohistochemical and CLOtest findings.	18089493
Inflammation, Obesity	Altered Intercellular Communication	Obesity is associated with substantial metabolic changes and subclinical inflammation.	18089656
Pain Distress Question, Inflammation, Fever, CTCAE	Altered Intercellular Communication	Patients with aspirin-provoked FDEIA have been reported previously as taking ordinary doses of aspirin for reducing pain, inflammation and fever.	18089939
Acute myocardial infarction, Inflammation	Altered Intercellular Communication	Use of inhaled corticosteroids may reduce the risk of acute myocardial infarction (MI) through reductions in systemic inflammation and C-reactive protein.	18090549
Inflammation	Altered Intercellular Communication	Our results do not support the hypothesis that inhaled corticosteroids protect against the risk of non-fatal MI by a reduction of systemic inflammation.	18090549
Stomach Carcinoma, Infection caused by Helicobacter pylori	Altered Intercellular Communication	It has been demonstrated that polymorphisms within inflammation-related genes are associated with risk of gastric carcinoma in Helicobacter pylori-infected individuals.	18090907
Granulomatous inflammation	Altered Intercellular Communication	A skin biopsy revealed granulomatous inflammation and spirochetes were demonstrated.	18090966
Inflammation, Vascular Diseases, Metabolic Syndrome X	Altered Intercellular Communication	Markers of inflammation and prevalence of vascular disease in patients with metabolic syndrome.	18091698
Ischemia, Inflammation	Altered Intercellular Communication	Concentration and the oxidase activity of Cp depend of the degree of lower extremity ischemia and correlates with the major markers of inflammation, such as CRP.	18091701
Inflammation, Retinitis Pigmentosa, polychondritis, Autoimmune Disorder, CTCAE	Altered Intercellular Communication	Relapsing polychondritis (RP) is a rare autoimmune disorder characterized by recurrent episodes of inflammation and destruction of cartilaginous tissues.	18092269
Inflammatory disorder of cartilage	Altered Intercellular Communication	The number of episodes of cartilaginous inflammation varied from one to eight.	18092269
Inflammation, Diverticulitis of small intestine	Altered Intercellular Communication	Diagnosis of small bowel diverticulitis is based on radiological findings, and computed tomography is the method of choice to demonstrate mural changes and the mesenteric extent of the inflammation.	18092289
Communicable Diseases, Appendicitis, CTCAE, Crohn Disease	Altered Intercellular Communication	The differential diagnosis for any inflammatory process in the right lower quadrant of the abdomen includes appendicitis, Crohn's disease, and other infectious and inflammatory conditions of the terminal ileum and cecum.	18092289
Inflammation, Intussusception, Neoplasms, Unknown (origin) (qualifier value), Crohn Disease, Tissue Adhesions	Altered Intercellular Communication	Seven had,enteroenteric intussusceptions from benign neoplasms (two), adhesions (one), local inflammation (one), previous anastomosis (one), Crohn's disease (one), and idiopathic (one).	18092641
Malignant tumor of colon, Tubulovillous adenoma, Inflammation, Intussusception, Unknown (origin) (qualifier value), melanoma, Cecum Carcinoma, Structure of ileocolic vein	Altered Intercellular Communication	Three had ileocolic disease, including cecal cancer (one), metastatic melanoma (one) and idiopathic (one; whereas five patients had colocolonic intussusception from colon cancer (three), tubulovillous adenoma (one), and local inflammation (one).	18092641
Acute and chronic inflammation	Altered Intercellular Communication	Rapid tumour-like growth of giant filiform polyposis in a patient without a history of chronic bowel inflammation.	18092966
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Long-term inflammation of the colonic mucosa during chronic inflammatory bowel disease with alternating periods of ulceration and healing may lead to the formation of finger-like projections, so-called filiform polyps.	18092966
Acute and chronic inflammation	Altered Intercellular Communication	We present a case of giant obstructing filiform polyposis in a patient without previous evidence of chronic bowel inflammation.	18092966
Inflammation	Altered Intercellular Communication	During the post-operative follow-up period, the patient developed symptoms and signs of distal bowel inflammation.	18092966
Inflammation, Ischemic stroke, Thrombophilia	Altered Intercellular Communication	There is increasing evidence that inflammation and hypercoagulability play an important role in the pathophysiology of acute ischaemic stroke.	18093263
Cessation of life, Inflammation, Observation Method - Coagulation, Ischemic stroke	Altered Intercellular Communication	CRP and fibrinogen levels can predict independently the risk of early death in middle-aged ischaemic stroke patients emphasizing the role of inflammation and coagulation in the evolution of ischaemic stroke.	18093263
Inflammation, Lofgrens syndrome, Sarcoidosis, Conjunctivitis, Arthritis, Erythema Nodosum, Paratracheal lymphadenopathy	Altered Intercellular Communication	Lofgren's syndrome is an acute form of sarcoidosis that mostly presents with erythema nodosum, periarticular ankle inflammation, arthritis, conjunctivitis, and unilateral or bilateral hilar or right paratracheal lymphadenopathy.	18093455
Aggressive behavior, Frontotemporal dementia	Altered Intercellular Communication	In FTD, increased activity of dopaminergic neurotransmission and altered serotonergic modulation of dopaminergic neurotransmission is associated with agitated and aggressive behavior respectively.	18093695
Aggressive behavior, Agitation, Frontotemporal dementia	Altered Intercellular Communication	The dopaminergic neurotransmitter system is associated with aggression and agitation in frontotemporal dementia.	18093695
Inflammation, Hypertension, CTCAE, Atherosclerosis	Altered Intercellular Communication	Chronic sub-clinical inflammation observed in hypertension plays a prominent role in the progression of atherosclerosis.	18093792
Inflammation, Hypertension, CTCAE, Obesity	Altered Intercellular Communication	In conclusion, our findings show that plasma tHcy is a determinant of TNF-alpha in hypertension and that obesity or a history of vascular events aggravates inflammation in patients with hypertension.	18093792
Communicable Diseases, Abnormal prostate morphology, Inflammation	Altered Intercellular Communication	It is known that severe infection and inflammation lead to hemostatic abnormalities.	18094569
Communicable Diseases, Inflammation	Altered Intercellular Communication	Recently, much attention is focused on the mechanisms of infection or inflammation and on how it plays a central role in effecting the coagulation system.	18094569
Degenerative polyarthritis, Inflammation, cell injury	Altered Intercellular Communication	Our results also suggest that the higher stages of osteoarthritis might be related to the increased inflammation and cell damage on joint cartilage due to PVB19.	18096351
Communicable Diseases, Inflammation, Cystitis	Altered Intercellular Communication	The Korean Association of Urogenital Tract Infection and Inflammation (KAUTII) conducted a survey of the antimicrobial susceptibility patterns of uropathogens responsible for female acute uncomplicated cystitis in South Korea in 2006.	18096373
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Intrathecal inflammation has been suggested to play an important role in the pathogenesis of Alzheimer's disease (AD).	18097142
Inflammation, Data types - Address	Altered Intercellular Communication	Our results suggest that intrathecal inflammation increases in association with the severity of MTA in AD.	18097142
Presenile dementia, Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation is associated with Alzheimer's disease (AD) and dementia.	18097143
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Patients who were infected by H. pylori had a significantly higher degree of inflammation than those who were not.	18097287
Mucous Membrane, Stomach Carcinoma, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Our results suggested that functional promoter polymorphisms of the MIF gene are associated with the progression of gastric mucosal inflammation and the development of mucosal atrophy at an early stage in life and these genotypes may increase the risk for the subsequent development of gastric cancer, especially the intestinal type, in older subjects.	18097599
Inflammation, Leukocytosis, Fever, CTCAE, Specimen Source Codes - Abscess, Communicable Diseases, Hypotension, CTCAE, Systemic Inflammatory Response Syndrome, Empyema, Bacteremia, Cholangitis	Altered Intercellular Communication	Illness was staged as none (no clinical infection or inflammation), SIRS (fever, leukocytosis), severe (cholangitis, abscess, empyema), or MODS (bacteremia, hypotension, organ dysfunction/failure).	18154938
Inflammation, Malnutrition, Diabetes Mellitus	Altered Intercellular Communication	Blood lead levels, malnutrition, inflammation, and mortality in patients with diabetes treated by long-term hemodialysis.	18155539
Inflammation, Malnutrition	Altered Intercellular Communication	Malnutrition, defined as serum albumin level less than 3.6 g/dL, and inflammation, defined as high-sensitivity C-reactive protein level greater than 3 mg/dL, for cross-sectional analyses.	18155539
Inflammation, Malnutrition	Altered Intercellular Communication	At baseline, patients with abnormal BLLs had a greater proportion of malnutrition (14.7% versus 1.5% and 11.6%; P = 0.01) and inflammation (76.5% versus 52.3% and 50.9%; P = 0.01) than those with low- and high-normal BLLs.	18155539
HD Term Type, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	BLL may contribute to inflammation and nutritional status in long-term HD patients with diabetes on long-term HD therapy and may relate to 1-year mortality in these patients.	18155539
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Cranial MRI showed left capsulothalamic inflammation and a vasculitis.	18155890
ovarian neoplasm	Altered Intercellular Communication	Evaluation of an inflammation-based prognostic score in patients with advanced ovarian cancer.	18155897
ovarian neoplasm	Altered Intercellular Communication	The aim of this study was to validate whether an inflammation-based prognostic score (Glasgow Prognostic Score, GPS) is associated with survival in patients with advanced stage (stage III/IV) ovarian cancer.	18155897
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	The prognostic role of inflammation in peripheral arterial disease (PAD) remains to be conclusively established.	18156137
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP), an exquisitely sensitive systemic marker of inflammation, has emerged as an independent predictor of cardiovascular diseases (CVD).	18156284
Lung Injury, Pneumonitis	Altered Intercellular Communication	Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents pulmonary inflammation in patients without preexisting lung injury.	18156881
Lung Injury, Pneumonitis	Altered Intercellular Communication	The use of lower tidal volumes and PEEP may limit pulmonary inflammation in mechanically ventilated patients without preexisting lung injury.	18156881
APP gene, Aortic Aneurysm, Abdominal, atherosclerotic	Altered Intercellular Communication	Atherosclerotic inflammation with a possible role of infectious agents can contribute to the pathogenesis of abdominal aortic aneurysms (AAA).	18157418
Inflammation, Coronary Artery Disease, Atherosclerosis	Altered Intercellular Communication	Inflammation is one of the major components of atherosclerosis which is the underlying disorder that leads to various diseases including coronary artery disease (CAD).	18157711
Inflammation, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	Variations in the genes involved in various molecular pathways of inflammation have been implicated to exaggerated atherosclerosis and the risk of cardiovascular diseases.	18157711
Inflammation, Atherosclerosis	Altered Intercellular Communication	Previous studies showed a pivotal role of inflammation in the progression of atherosclerosis and the prognostic value of several biomarkers.	18157956
Inflammation, Pain Distress Question, Stiffness, Refractory anemias, Autoimmune Disorder, CTCAE, Rheumatoid Arthritis, destruction joint, Joint swelling	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by inflammation of synovial tissues that leads to joint swelling, stiffness and pain, and progressive joint destruction.	18158087
Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cerebrovascular accident	Altered Intercellular Communication	Sequence variations in genes involved in inflammation system are known to contribute to the risk of cardiovascular diseases (CVD) including stroke.	18158110
Inflammation, Nephrogenic rest, Fibrosis Assessment, Oral cleft	Altered Intercellular Communication	The typical histology in nephrogenic systemic fibrosis consists of haphazardly arranged dermal collagen bundles with clefting, collagenous change which extends into the subcutaneous septa, mucin deposition, fibroblast proliferation, and increased elastic fibers with minimal inflammation.	18158925
Inflammation, Complication Aspects, atherosclerotic	Altered Intercellular Communication	Current evidence supports the central role of inflammation in all phases of the atherosclerotic process, including its thrombotic complications.	18159101
Inflammation	Altered Intercellular Communication	The presence of significant levels and activity of inflammatory mediators in saliva suggests that the oral cavity of healthy subjects may be in a constant low state of inflammation associated with age.	18159234
Inflammation	Altered Intercellular Communication	Conventional brain MRI frequently shows WM lesions in HTLV-I-infected individuals suggesting potential early central nervous system inflammation with rare development of progressive disease.	18160007
Inflammation, Ventricular Dysfunction, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Whether the association of inflammation with incident HF is explained by worse baseline left ventricular dysfunction or by underlying CHD is unknown.	18160340
Inflammation, Cardiovascular Diseases, Histiocytic syndrome, Hypopituitarism, Histiocytosis, Langerhans-Cell	Altered Intercellular Communication	Langerhans-cell histiocytosis (LCH) is a rare disease with features of chronic inflammation and it may also induce hypopituitarism, conditions associated with an increased risk of cardiovascular diseases.	18160417
Inflammation, Abnormality of the abdominal organs, Portal Venous System, Portal Vein Thrombosis, Liver Cirrhosis	Altered Intercellular Communication	The etiology of portal vein thrombosis is often multifactorial, with various combinations of systemic factors (inherited or acquired prothrombotic conditions) and local precipitating factors (inflammation, injury to the portal venous system, cancer of the abdominal organs, cirrhosis).	18160613
Tuberculosis, Necrosis	Altered Intercellular Communication	The use of anti-tumor necrosis factor (TNF) agents as a treatment for chronic inflammatory conditions has been shown to be associated with an increased risk of developing tuberculosis.	18160618
Cataract, Acute inflammation	Altered Intercellular Communication	Intracameral triamcinolone acetonide to control postoperative inflammation following cataract surgery with phacoemulsification.	18162061
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	To explore the efficacy, safety and tolerability of 1 mg intracameral triamcinolone acetonide (TA) in controlling ocular inflammation in patients undergoing cataract surgery.	18162061
Gastrointestinal inflammation	Altered Intercellular Communication	ATG16L1 is a CD susceptibility gene without epistatic interaction with other CD susceptibility genes and is not upregulated in intestinal inflammation.	18162085
Inflammation	Altered Intercellular Communication	Aberrant accumulation of p53 protein and CEA expression in the cystic epithelium inside PS tissues show a relationship with chronic inflammation.	18162151
Glycogen Storage Disease Type V, Inflammation	Altered Intercellular Communication	Our results suggest that McArdle disease is associated with low-level systemic inflammation whereas appropriate exercise induces a similar response in McArdle patients and healthy controls, with a significant increase in the anti-inflammatory myokine IL-6.	18162322
Inflammation	Altered Intercellular Communication	Six out of 8 cases were accompanied by moderate to marked acute and chronic inflammation.	18162775
Inflammation, Fibrosis Assessment, Stasis, Edema	Altered Intercellular Communication	The analysis of the results of the above examination provided information on efficacy of the original method of semiquantitative assessment of local cell reactivity and qualitative composition of tissue elements (content of lymphocytes, plasmocytes, fibroblasts; the degree of development of the capillaries, fibrosis, stasis, edema, inflammation activity by neutrophil count).	18163071
Inflammation	Altered Intercellular Communication	Concentrations of these markers are associated with severity of patients and systemic inflammation syndrome, and also with the number of performed laparotomies.	18163111
Inflammation	Altered Intercellular Communication	While inflammation has been proposed to play an important role in both benign and malignant growth of the prostate, the stimuli for this inflammation remain poorly characterized.	18163428
prostatitis	Altered Intercellular Communication	Infectious pathogens are potential stimuli for prostatic inflammation.	18163428
Inflammation	Altered Intercellular Communication	There was no significant association between the presence of particular species of bacteria and histologic evidence of acute or chronic inflammation.	18163428
Inflammation, Arthritis	Altered Intercellular Communication	Antibody epitope specificity contributes significantly to the development of arthritis, and the early pathogenic events operate independent of inflammation both in vitro and in vivo.	18163493
Inflammation, Atherosclerosis	Altered Intercellular Communication	The role of in situ and remote inflammation in atherosclerosis is a major area of interest.	18163971
Autoimmune Diseases, Inflammation, Colonization	Altered Intercellular Communication	Further studies are needed on a Saccharomyces cerevisiae-based diet, related intestinal colonization, and associated inflammation, autoimmune disorders, and cardiovascular events.	18163971
Inflammation	Altered Intercellular Communication	Inflammation and increased metabolic activity associated with oxidative stress in irradiated normal tissues may contribute to both complications following radiotherapy and increased glucose uptake as detected by posttherapy fluorodeoxyglucose (FDG)-PET imaging.	18164842
Inflammation, Radiation Induced DNA Damage	Altered Intercellular Communication	These data support investigating hypermetabolic conditions associated with either inflammation, oxidative stress, or both, as causal agents for radiation-induced normal tissue damage.	18164842
Hepatic inflammation, Liver Cirrhosis, Hindi language	Altered Intercellular Communication	Patients with hepatic inflammation but no cirrhosis (HIN, n=20) revealed elevated serum interferon (IFN)-gamma and high frequency of IFN-gamma producing CD4 T(h1) cells compared to those with hepatic cirrhosis (HFC, n=20) that had high interleukin (IL)-5 and IL-5 producing CD4 T(h2) cells.	18165785
Sepsis, Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	In a prospective, longitudinal study, we investigated the association between decreased ADAMTS13 activity and impaired hemostasis, as well as organ dysfunctions in patients with systemic inflammation due to extracorporeal cardiopulmonary circuit or with severe sepsis.	18166799
Inflammation, Atherosclerosis, diabetic	Altered Intercellular Communication	Relation of plasma homocysteine levels to atherosclerotic vascular disease and inflammation markers in type 2 diabetic patients.	18166816
Inflammation, Vascular Diseases, Atherosclerosis	Altered Intercellular Communication	Both Hcy levels and inflammation markers were all significantly elevated in patients with atherosclerotic vascular disease when compared with patients without vascular disease.	18166816
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	Inflammation is not involved in the process by which Hcy leads atherosclerosis in type 2 diabetes.	18166816
Asthma, Bronchitis, Atopy	Altered Intercellular Communication	Atopic children have an increased risk for asthma, which is preceded by bronchial inflammation.	18167156
Pneumonitis	Altered Intercellular Communication	Exhaled breath condensate is another non-invasive method to measure lung inflammation.	18167156
Dermatitis, Atopic, Pneumonitis	Altered Intercellular Communication	The purpose of the present study was to find out if the severity of atopic eczema is associated with lung inflammation that can be observed with these non-invasive tests.	18167156
Inflammation, Dermatitis, Atopic	Altered Intercellular Communication	The results show that increased bronchial NO output is associated with eosinophilic inflammation and severe atopic eczema in patients without established asthma.	18167156
Diffuse Axonal Injury, Inflammation	Altered Intercellular Communication	Inflammation may not lead to the generation of anti-NF-L antibody which links to the axonal injury.	18167263
Liver carcinoma, Hepatitis, Fibrosis Assessment, Virus Diseases, Liver Cirrhosis	Altered Intercellular Communication	The identification of allelic polymorphisms in genes involved in the pathway leading to chronic viral infection, liver cirrhosis and, ultimately, hepatocellular carcinoma would provide insights to those factors leading to HBV replication, liver inflammation, fibrosis, and the carcinogenic process.	18171470
Muscle damage, Inflammation	Altered Intercellular Communication	Elderly patients and high force resistance exercise--a descriptive report: can an anabolic, muscle growth response occur without muscle damage or inflammation?	18171497
Muscle damage, Inflammation, muscle mass	Altered Intercellular Communication	Serum measures of muscle damage, inflammation, and an anabolic response are reported along with changes in muscle mass as measured with dual energy X-ray absorptiometry.	18171497
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Inflammation is a recognized risk factor for the vulnerable atherosclerotic plaque.	18171628
Inflammation, Colorectal Neoplasms, Obesity	Altered Intercellular Communication	The association between obesity and colorectal neoplasia may be mediated by inflammation.	18172326
Inflammation, Colorectal Neoplasms	Altered Intercellular Communication	Our findings indicate that systemic inflammation might be involved in the early development of colorectal neoplasia.	18172326
Inflammation, Malignant tumor of small intestine, Crohn Disease	Altered Intercellular Communication	Rarely, small bowel cancer can develop after a longstanding inflammation of Crohn's disease with a relatively higher incidence than the general population.	18172359
Bladder Diverticulum, Bladder Neoplasm, Inflammation, Neoplasms, Stricture of ureter, Specimen Type - Fistula, Nephrolithiasis, Urethral Stenosis, Transitional cell carcinoma of kidney	Altered Intercellular Communication	The virtual examination findings included urethral stricture, recto-urethral fistula, multiple bladder tumors, bladder tumor invading the distal ureter or urethra, bladder diverticula containing a tumor, ureteral stricture, renal transitional cell carcinoma, and renal calculi with inflammation.	18172706
Inflammation, Bitter	Altered Intercellular Communication	CSD was diagnosed depending on the history of direct contact with a cat (being scratched and bitten), together with the clinical features and histopathologic findings (necrotizing granulomatous inflammation concordant with CSD).	18173081
Inflammation	Altered Intercellular Communication	These results indicate that hypoxic conditions with inflammation modulate the tenascin-C expression in synovial fibroblasts, but not in disk cells.	18173448
Pressure Ulcer, Inflammation	Altered Intercellular Communication	This caused inflammation and continuous decubitus ulcers on the posterior surfaces of both earlobes.	18173517
Inflammation, Dental Plaque	Altered Intercellular Communication	Older SO participants were more likely to have fewer than 21 teeth and to have fillings, untreated decay, gum inflammation and heavy plaque levels.	18173570
Inflammation	Altered Intercellular Communication	The number of lymphatic vessels was positively related to the severity of synovial inflammation.	18174217
Cartilage, Obesity	Altered Intercellular Communication	By contrast, obesity related knee focal cartilage defects may be more related to non-hormonal factors.	18174218
Inflammation, Impaired cognition	Altered Intercellular Communication	This study shows that lower serum albumin levels are independently associated with lower MMSE scores in hip fractured elderly patients, supporting the possible role of chronic low-grade inflammation in age-related cognitive decline.	18174316
ARCN1 gene, Respiratory physiology, Abnormal inflammatory response, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Abnormal inflammation and accelerated decline in lung function occur in patients with chronic obstructive pulmonary disease (COPD).	18174544
Kallmann Syndrome, Hypogonadism, Anosmia	Altered Intercellular Communication	Kallmann's syndrome is a rare genetic disorder due to abnormal migration of olfactory axons and gonadotropin releasing hormone producing neurons, characterized by hypogonadism and anosmia.	18174649
Weight Gain, Inflammation	Altered Intercellular Communication	This increased risk may be mediated by inflammation, but no long-term data are available on the effect of weight gain on systemic inflammation.	18175734
Weight Gain, Inflammation	Altered Intercellular Communication	We tested the hypothesis that weight gain is associated with an increase in systemic inflammation during a 9-y period.	18175734
Inflammation	Altered Intercellular Communication	During a 9-y period, an increase in weight is associated with an increase in systemic inflammation.	18175734
Cholangiocarcinoma, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	Pathologically, mucin-producing cholangiocarcinoma was confirmed, but the wall thickening was due to inflammation not cancer invasion.	18176044
Inflammation, Edema	Altered Intercellular Communication	Gastrointestinal endoscopy examination discovered generalized edema in the intestinal wall whereas the biopsy showed chronic inflammation only.	18176138
Inflammation, Oral infection	Altered Intercellular Communication	It was an immunocompetent patient presenting dental inflammation but not oral infection.	18176393
Trachoma , Chlamydia trachomatis, Conjunctivitis	Altered Intercellular Communication	Various animal models of trachoma show that urogenital C. trachomatis strains and other species of the family Chlamydiaceae produce severe conjunctival inflammation and scarring similar to that of the ocular C. trachomatis strains.	18177205
Inflammation, Heat-Shock Response, HSPD1 wt Allele, Conjunctival scar	Altered Intercellular Communication	Furthermore, C. trachomatis heat shock protein 60 (Hsp60) has been implicated in inflammation and conjunctival scarring but the role of other Chlamydiaceae Hsp60 in disease pathogenesis has not been examined.	18177205
Communicable Diseases, Chlamydia trachomatis, Infection, Conjunctivitis	Altered Intercellular Communication	Of 80 (63%; n = 127) infected individuals, 28 (35%) had infection with C. psittaci, or C. pneumoniae, or both; single and dual infections with C. psittaci and C. pneumoniae were significantly associated with severe conjunctival inflammation (OR 4.25 [95% confidence interval (CI), 2.9-11.3], p = 0.009] as were single infections with C. trachomatis (OR 5.7 [95% CI, 3.8-10.1], p = 0.002).	18177205
Inflammation, Infection	Altered Intercellular Communication	The evidence for viable (RNA-positive) organisms of all three species in single and coinfections, the significant association of these infections with severe inflammation, and the significant association of tear and serum IgG responses to Chlamydiaceae Hsp60 with inflammation and scarring, support the role of all three species in disease pathogenesis.	18177205
Inflammation, Vascular calcification	Altered Intercellular Communication	Osteopontin (OPN) and osteoprotegerin (OPG) are well-known vascular calcification inhibitors, which have been recently demonstrated to correlate with inflammation and cardiovascular events incidence.	18178454
Inflammation, Obesity	Altered Intercellular Communication	Low-grade inflammation and muscle strength may partially mediate the association between obesity and walking limitation.	18179481
Inflammation	Altered Intercellular Communication	These findings suggest that inflammation may contribute to the pathogenesis of cardiovascular autonomic decline in older adults.	18179502
Inflammation	Altered Intercellular Communication	Interleukin-6 concentrations in wound fluids rather than serological markers are useful in assessing bacterial triggers of ulcer inflammation.	18179556
Gastritis	Altered Intercellular Communication	The Th2 cytokine IL-4 might limit H. pylori associated gastric inflammation and favour H. pylori clearance.	18179773
Intestinal metaplasia, Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Neither the SNPs nor the IL-4RA haplotype correlated with disease diagnosis, H. pylori infection, degree of mucosal inflammation or intestinal metaplasia.	18179773
Inflammation, Heart, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Suspected chronic myocarditis at cardiac MR: diagnostic accuracy and association with immunohistologically detected inflammation and viral persistence.	18180335
Myocarditis, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	To retrospectively compare the diagnostic accuracy of three cardiac magnetic resonance (MR) imaging approaches for the detection of histologic and immunohistologic criteria (reference standard) proved myocardial inflammation in patients clinically suspected of having chronic myocarditis (CMC).	18180335
Inflammation	Altered Intercellular Communication	In patients clinically suspected of having CMC, increased gRE and ER indicating inflammation were common findings that could be confirmed at immunohistologic analysis, whereas LE had low sensitivity and accuracy.	18180335
Inflammation	Altered Intercellular Communication	Cardiac MR imaging may be helpful in detecting intramyocardial inflammation noninvasively, but it fails to depict viral persistence.	18180335
Inflammation, Fracture, Infection	Altered Intercellular Communication	During the 9-month follow-up period, we did not observe any new symptomatic fractures or infections in treated patients, but we found a reduction in parameters indicating inflammation; no differences were found in biochemical parameters.	18180602
Liver Dysfunction, Chronic Kidney Diseases	Altered Intercellular Communication	Patients on vitamin K antagonists, with acute inflammatory conditions (as measured by CRP) or liver dysfunction were excluded PZ levels were reduced in CKD patients when compared to levels in the control group (1.35 mug/mL vs 1.80 respectively, p = 0.022).	18180611
Inflammation, Infection	Altered Intercellular Communication	Dengue infections may affect the liver, causing inflammation and compromising its function.	18180838
Inflammation	Altered Intercellular Communication	The biopsy specimen demonstrated not only inflammation but infiltration of leukemic cells as well.	18181773
Inflammation, Liver Failure, Acute, Injury of liver, GTF2A1L wt Allele	Altered Intercellular Communication	Cytokines are released within the liver in response to hepatic injury, and acute liver failure (ALF) triggers systemic inflammation.	18181803
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	From a cumulative dosage of 3 to 4 g, there is fibrosis formation, inflammation enhancement in the portal area and fibrous septa, configuring regenerative nodes.	18181969
Inflammation, Squamous cell carcinoma of esophagus	Altered Intercellular Communication	We demonstrated IL-8 that positively correlated with inflammation status of ESCC patients.	18182303
Pancreatitis	Altered Intercellular Communication	Recent studies suggest that alcohol represents only a risk factor for developing pancreatic inflammation in genetic or environmental susceptible subjects.	18182741
Acute hemorrhage, Infarction, Headache, physiopathological, Visual symptoms	Altered Intercellular Communication	Pituitary Apoplexy (PA) is associated with the sudden onset of headache, visual symptoms, altered mental status, and hormonal dysfunction due to acute hemorrhage or infarction of the pituitary gland.	18183804
Inflammation	Altered Intercellular Communication	The significant association of cTNT and NT-proBNP with non-native fistulas (catheter or graft) may be due to the chronic inflammation commonly caused by these devices.	18184522
Inflammation, Endothelium	Altered Intercellular Communication	This toxin induces endothelial injury, apoptosis and inflammation.	18184524
Inflammatory abnormality of the eye, Hypopyon	Altered Intercellular Communication	Ocular inflammation occurred in six eyes (0.6%): four eyes with sterile hypopyon and two eyes without hypopyon.	18185140
Inflammation, Coronary Artery Disease, Kidney damage	Altered Intercellular Communication	Among persons with prevalent coronary artery disease, biomarkers reflecting hemodynamic stress, kidney damage, and inflammation added significant risk discrimination for cardiovascular events.	18187073
Inflammation	Altered Intercellular Communication	Relationship between natriuretic peptides and inflammation: proteomic evidence obtained during acute cellular cardiac allograft rejection in humans.	18187084
Inflammation, Chronic Kidney Diseases, Premature calcification of mitral annulus	Altered Intercellular Communication	Mitral annular calcification is associated with reduced left ventricular function and inflammation in patients with chronic kidney disease.	18187299
Inflammation, MARCKS wt Allele, Atherosclerosis, Left Ventricular Function, Chronic Kidney Diseases	Altered Intercellular Communication	In patients with CKD, MAC is associated with inflammation, reduced left ventricular function, and treatment with dialysis, independent of the degree of subclinical atherosclerosis.	18187299
Inflammation, Exophthalmos, Edema	Altered Intercellular Communication	Examination revealed periorbital edema and inflammation but no proptosis.	18187989
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	SF 12-scores closely correlated with degrees of inflammation and fibrosis (p<0.001, respectively).	18188813
Granulomatous inflammation, Crohn Disease	Altered Intercellular Communication	A biopsy specimen demonstrated granulomatous inflammation characteristic of Crohn disease.	18189031
Granulomatous inflammation, Oral Manifestations, Crohn Disease	Altered Intercellular Communication	Perianal skin tags with granulomatous inflammation are one of many perianal manifestations of Crohn disease.	18189031
Inflammation	Altered Intercellular Communication	They had myxoid and hyaline stroma with dense acute and chronic inflammation.	18190443
Inflammation, Diabetes Mellitus, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Inflammation is associated with obesity, the metabolic syndrome, and diabetes.	18191048
Inflammation, Weight decreased	Altered Intercellular Communication	Weight loss altered gene expression of cytokines related to inflammation and the immune response in PBMCs.	18191048
Uveomeningoencephalitic Syndrome, Choroiditis	Altered Intercellular Communication	Concomitant choroidal inflammation during anterior segment recurrence in Vogt-Koyanagi-Harada disease.	18191100
Uveomeningoencephalitic Syndrome, Choroiditis	Altered Intercellular Communication	To determine whether clinically isolated anterior segment recurrence is associated with concomitant subclinical choroidal inflammation in Vogt-Koyanagi-Harada (VKH) disease.	18191100
Inflammation, Fluorescence	Altered Intercellular Communication	ICGA showed early large vessel hyperfluorescence, becoming fuzzy in character in the intermediate phase in 11 of 12 eyes with AC inflammation.	18191100
Choroiditis	Altered Intercellular Communication	Isolated anterior segment recurrence in VKH disease may occur concomitantly with subclinical choroidal inflammation and requires systemic therapy.	18191100
Cessation of life, Inflammation, Ischemic stroke	Altered Intercellular Communication	High sICAM-1 levels on admission are associated with early death in ischaemic middle-aged stroke patients suggesting a pathogenetic role of inflammation in the evolution of ischaemic stroke.	18191248
Inflammation, Hemorrhage, Transitional cell hyperplasia	Altered Intercellular Communication	Rats dying early at > or =300 mg/kg/day had transitional cell hyperplasia with inflammation and hemorrhage of the bladder wall.	18191429
Suppurative cholangitis, Inflammation, Communicable Diseases	Altered Intercellular Communication	Suppurative cholangitis is characterized by obstruction, inflammation, and pyogenic infection of the biliary tract.	18191523
Inflammation, Thoracic aorta calcification, Atherosclerosis	Altered Intercellular Communication	Inflammation and descending thoracic aortic calcification as detected by computed tomography: the Multi-Ethnic Study of Atherosclerosis.	18191862
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is related to many stages of atherosclerosis, and inflammatory markers have been associated with both atherosclerosis and future cardiovascular events.	18191862
vascular inflammations	Altered Intercellular Communication	In addition, PlGF has been known to be a useful biomarker of vascular inflammation.	18192038
Barrett Esophagus, Inflammation	Altered Intercellular Communication	Severity of mucosal inflammation is shown to be associated with Barrett's esophagus (BE) development in animals.	18192685
Carcinogenesis, Pancreatic carcinoma	Altered Intercellular Communication	The fact that inflammation-sensitive proteins were identified as increased in pancreatic cancer sera supports the hypothesis that inflammatory-driven processes are involved in pancreatic carcinogenesis.	18192883
Inflammation, Heart failure	Altered Intercellular Communication	The association between vitamin D and inflammation with the 6-minute walk and frailty in patients with heart failure.	18194227
Peripheral Vascular Diseases, Inflammation, Thrombosis	Altered Intercellular Communication	Biomarkers of inflammation and thrombosis as predictors of near-term mortality in patients with peripheral arterial disease: a cohort study.	18195333
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	To determine whether elevated levels of D-dimer and biomarkers of inflammation were more closely associated with near-term than long-term mortality in patients with lower-extremity peripheral arterial disease (PAD) and whether greater increases in biomarker levels were associated with higher mortality rates during the first year after the increase than during later years.	18195333
Inflammation, Fibrosis Assessment, Chondroma	Altered Intercellular Communication	Among the six patients with PFP alterations, histopathologic examination revealed fibrosis and adventitious bursae in two, fibrosis with inflammation in three, and a soft-tissue chondroma in one.	18195378
Conjunctivitis, Failure (biologic function)	Altered Intercellular Communication	Chronic situations like long-term use of topical medications induces conjunctival inflammation and is also a significant risk factor for failure of filtering surgery.	18196260
Inflammation, Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	The urokinase-type plasminogen activator (uPA) and the plasminogen activator inhibitor-1 (PAI-1) are involved in tumor invasion and metastasis as well as wound healing and inflammation.	18196271
ACSM3 gene, Inflammation, Systemic Inflammatory Response Syndrome, Vasospasm	Altered Intercellular Communication	We ascertained the frequency and predictors of SIRS after spontaneous SAH, and determined whether degree of early systemic inflammation predicted the occurrence of vasospasm and clinical outcome.	18196475
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Inflammation has been hypothesized to increase prostate cancer risk.	18196539
Allergic, IL13 gene	Altered Intercellular Communication	The increased levels of sensory sodium channels in allergic and nonallergic rhinitis may contribute to the hypersensitive state, irrespective of the degree of active inflammation.	18197135
Inflammation, Gastrointestinal mucositis, Malignant Head and Neck Neoplasm	Altered Intercellular Communication	Apoptotic and inflammation markers in oral mucositis in head and neck cancer patients receiving radiotherapy: preliminary report.	18197435
Inflammation, Head and neck injury, Gastrointestinal mucositis	Altered Intercellular Communication	Our preliminary results indicate an induction of apoptosis and inflammation in the oral mucosa in patients developing mucositis during radiotherapy for head/neck cancer.	18197435
Communicable Diseases, Chlamydia, Inflammation	Altered Intercellular Communication	The association between past Chlamydia pneumoniae infection and markers of chronic inflammation in obese women.	18197444
Inflammation, Obesity	Altered Intercellular Communication	It has been widely accepted that obesity is associated with chronic, low-grade inflammation that affects the adipose tissue as well as the entire system.	18197444
Communicable Diseases, Inflammation	Altered Intercellular Communication	In conclusion, past C. pneumoniae infection was not associated with changes in chronic inflammation markers in premenopausal obese women.	18197444
Inflammation, Anemia, Hypoalbuminemia, Ventricular hypertrophy	Altered Intercellular Communication	Older age, anemia, absence of residual renal function, hypoalbuminemia, inflammation, impaired Ca and P metabolism, and left ventricular hypertrophy were significantly higher in Group 1 than in Group 2.	18197541
Inflammation, Headache, Pain Distress Question	Altered Intercellular Communication	The presence of inflammation in the perivascular tissue of the retro-orbital region has been presented as a possible mechanism behind the pain and the sympatheticoplegia sometimes observed during headache attacks.	18197885
Inflammation, Chronic Obstructive Airway Disease, Asthma	Altered Intercellular Communication	Systemic inflammation in chronic obstructive pulmonary disease and asthma: Similarities and differences.	18197923
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	While recent studies have shown that patients with COPD and patients with asthma exhibit evidence of airway and systemic inflammation, markers of systemic inflammation have not been compared between the two diseases.	18197923
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	Although COPD and asthma share common markers of systemic inflammation, serum levels of TGF-beta1 and alpha1-AT may reflect differences between the diseases.	18197923
Inflammation, Exacerbation	Altered Intercellular Communication	Increased systemic inflammation is a risk factor for COPD exacerbations.	18198263
Inflammation, Exacerbation	Altered Intercellular Communication	COPD exacerbations are associated with an increase in local and systemic inflammation.	18198263
ARCN1 gene, Inflammation	Altered Intercellular Communication	Data of a previously published study in a well-characterized COPD cohort were analyzed to define predictive factors of acute exacerbations, particularly focusing on systemic inflammation.	18198263
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	This study demonstrates that besides lung function impairment systemic inflammation manifested by elevated fibrinogen levels is an independent risk factor for exacerbations of COPD.	18198263
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	Attenuation of systemic inflammation may offer new perspectives in the management of COPD patients to reduce the burden of exacerbations.	18198263
vascular inflammations, square decimeter	Altered Intercellular Communication	In DM2 patients, daily sildenafil administration improves endothelial function and reduces markers of vascular inflammation, suggesting that the diabetes-induced impairment of endothelial function may be improved by prolonged phosphodiesterase-5 inhibition.	18199130
Adenocarcinoma, Inflammation, Carcinoma, prostatitis	Altered Intercellular Communication	To elucidate the clinicopathological characteristics of AIP-associated prostatitis (AIP-P), the clinicopathological findings of AIP-P patients were evaluated, and the immunohistochemical expression of the IgG subclasses (IgG1, IgG2, IgG3, and IgG4) in six AIP-P patients was compared with that in 10 control patients who were clinically diagnosed as suspicious for carcinoma but who had focal inflammation without adenocarcinoma on histological examination of the prostate.	18199162
Inflammation, Psoriasis, Failure (biologic function), Inflammatory disorder, Helper-Inducer T-Lymphocyte	Altered Intercellular Communication	Failure to regulate prolonged T-helper 1-mediated inflammation is central to psoriasis and is a feature shared with other inflammatory diseases.	18200047
Inflammation, Virus Diseases, Psoriasis	Altered Intercellular Communication	IFNs are important initiators/regulators of inflammation that among other things can affect the expression of the main genetic determinant in psoriasis, namely HLA-C. Externally administered IFN-alpha, as in patients treated for viral infections, and IFN-alpha produced by plasmacytoid dendritic cells is a known trigger of psoriasis.	18200047
Inflammation, Psoriasis	Altered Intercellular Communication	The hypothesis underlying this study was that polymorphisms in the IRF5 gene contribute to inadequate control of inflammation in psoriasis.	18200047
Limbic Encephalitis, Drug Hypersensitivity Syndrome	Altered Intercellular Communication	Syndrome of inappropriate secretion of antidiuretic hormone associated with limbic encephalitis in a patient with drug-induced hypersensitivity syndrome.	18201256
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Identifying aortic plaque inflammation as a potential cause of stroke.	18202222
Hepatitis C	Altered Intercellular Communication	We identified the presence of T cell and plasmacytoid dendritic cell infiltrates within all biopsy specimens, suggesting they could be a source of hepatic interferon in the setting of hepatitis C and chronic inflammatory condition.	18203148
Inflammation, Atherosclerosis, Autoimmune Diseases, Rheumatoid Arthritis, Endothelial dysfunction	Altered Intercellular Communication	Endothelial dysfunction and atherosclerosis in rheumatoid arthritis: a multiparametric analysis using imaging techniques and laboratory markers of inflammation and autoimmunity.	18203326
Inflammation, Actinomyces, Specimen Source Codes - Abscess	Altered Intercellular Communication	Histopathologic evaluation revealed chronic inflammation with abscess formation and clusters of Actinomyces colonies.	18203542
Inflammation	Altered Intercellular Communication	It also leads to a downregulation of surfactant protein D expression and an underlying chronic inflammation in these lungs.	18203811
Inflammation, Hypoxia	Altered Intercellular Communication	Neovascularisation is a principal vascular response in chronic inflammation and hypoxia.	18204190
Thrombotic Microangiopathies, Inflammation	Altered Intercellular Communication	Brain, peripheral nerve, muscle, kidney and colon biopsies have revealed a multi organ small vessel involvement with partly altered endothelium, perivascular inflammation and thrombotic microangiopathy.	18204807
Communicable Diseases, Intraocular inflammation	Altered Intercellular Communication	Injection of drugs into the vitreous can lead to intraocular inflammation through infectious and non-infectious processes.	18204851
Inflammation, Endophthalmitis, CTCAE, Failure (biologic function)	Altered Intercellular Communication	Failure to recognize an eye with anterior chamber and vitreous cell as sterile inflammation can lead to unnecessary treatment for endophthalmitis.	18204851
Intraocular inflammation	Altered Intercellular Communication	With its rising use, it is important to be aware of its potential to be associated with intraocular inflammation.	18204851
Degenerative polyarthritis, Inflammation, Inflammatory, Inflammatory disorder	Altered Intercellular Communication	Osteoarthritis (OA) is largely considered to be a non-inflammatory disease, although there is compelling evidence that subclinical inflammation is a common event, even in the absence of acute inflammatory flares.	18205004
Inflammation, Pancreatitis, Periodontitis, Pancreatic carcinoma	Altered Intercellular Communication	Pancreatic cancer risk has been linked to chronic pancreatitis and periodontitis, suggesting a role for inflammation in disease etiology.	18205184
glycation, Inflammation	Altered Intercellular Communication	Advanced glycation endproducts (AGEs) and their receptors, receptor for advanced glycation endproducts (RAGE), are novel groups of molecules with roles in inflammation, cytokine activation, and promotion of cell growth.	18206396
Pain Distress Question	Altered Intercellular Communication	Abnormal regulation of the hypothalamic-pituitary-adrenal axis and diurnal cortisol rhythms are associated with several pain and chronic inflammatory conditions.	18207189
Kidney Failure, Neoplasms	Altered Intercellular Communication	The insufficiency of hormonal theory to explain solely the pathogenesis of this tumor might reveal other potential factors that have not been discussed in earlier literature.	18207493
Inflammation	Altered Intercellular Communication	No clinical and sub-clinical inflammation was apparent in DS patients.	18207581
Pneumonitis	Altered Intercellular Communication	Complications after lung radiofrequency ablation: risk factors for lung inflammation.	18208852
Pneumonitis	Altered Intercellular Communication	The relationships between CRP values and patient baselines were evaluated to identify factors affecting lung inflammation.	18208852
Pneumonia, Interstitial, Pleurisy	Altered Intercellular Communication	Inflammation-related complications such as interstitial pneumonia (n = 2) and aseptic pleuritis (n = 2) developed in four sessions (1.2%).	18208852
Pneumonitis	Altered Intercellular Communication	In conclusion, although the incidence rate is low, fatal lung inflammation may develop after lung RF ablation.	18208852
Pneumonitis, Neoplasms	Altered Intercellular Communication	Large tumour size and previous external-beam radiotherapy are risk factors for severe lung inflammation.	18208852
Neuromyelitis Optica, Myelitis, N-nitrosomorpholine, Demyelinating Diseases	Altered Intercellular Communication	Neuromyelitis optica (NMO) is a demyelinating disease of the central nervous system characterized by severe episodes of optic nerve and spinal cord inflammation.	18208886
Inflammation	Altered Intercellular Communication	Recent data, however, have linked PPAR-gamma to several genes involved in inflammation.	18209172
Inflammation, Dermatitis, Atopic, Data types - Address	Altered Intercellular Communication	Among others, these pathways reduce certain inflammatory mediators in the skin and regulate epidermal barrier homeostasis, alterations of which contribute to the inflammation associated with atopic dermatitis (AD).	18209172
Orbital Pseudotumor	Altered Intercellular Communication	Incisional biopsy with histopathology demonstrated idiopathic orbital inflammation.	18209649
Vasculitis, CTCAE	Altered Intercellular Communication	Mondor's disease (MD) is considered an inflammatory condition of superficial vasculitis that develops mainly in the anterolateral thoracoabdominal wall.	18211409
Inflammation, Ocular Surface Disease Index	Altered Intercellular Communication	Abnormal keratocytes and stromal inflammation in chronic phase of severe ocular surface diseases with stem cell deficiency.	18211946
Inflammation, Ocular Cicatricial Pemphigoid, Stevens-Johnson Syndrome, CTCAE, HSPG2 wt Allele, Burn injury	Altered Intercellular Communication	Stevens-Johnson syndrome (SJS), ocular cicatricial pemphigoid (OCP) and alkali burns are associated with chronic, severe inflammation of the ocular surface that occasionally lead to corneal stem cell deficiencies.	18211946
HSPG2 wt Allele, Inflammation, Burn injury	Altered Intercellular Communication	These findings indicate that the keratocytes are abnormal and inflammation is still present in the corneal stroma in the chronic phase of SJS, OCP and alkali burns.	18211946
Kidney Failure, Chronic	Altered Intercellular Communication	Clinical value of the malnutrition-inflammation-atherosclerosis syndrome for long-term prediction of cardiovascular mortality in patients with end-stage renal disease: a 5-year prospective study.	18212491
Anemia	Altered Intercellular Communication	This study compared clinical measures of adequacy, anemia, and nutrition/inflammation in prevalent hemodialysis patients in 2003 by access type.	18212514
Papillary, Inflammation	Altered Intercellular Communication	This study revealed that, in the absence of calcium channel blockers, gingival inflammation, represented by the papillary bleeding index, was a variable associated with Tcr-induced GO, indicating the importance of periodontal maintenance of subjects under Tcr immunosuppressive regimens.	18212628
Unspecified visual loss	Altered Intercellular Communication	Enlargement of the PR-positive meningioma in the hormonal milieu of pregnancy might have contributed additionally to visual loss.	18213441
Inflammation	Altered Intercellular Communication	Induced sputum cytology and local and systemic markers of inflammation may be helpful to characterize disease status and progression in these patients.	18213643
Inflammation, Primary malignant neoplasm, Colorectal Adenomatous Polyp	Altered Intercellular Communication	Cox-2 is an inducible enzyme that regulates prostaglandin synthesis and it is overexpressed at sites of inflammation, in colorectal adenomatous polyps and cancer.	18214062
allergic inflammation	Altered Intercellular Communication	A more favorable response to fluticasone over montelukast was associated with more severe disease or markers of allergic inflammation.	18214538
Inflammation	Altered Intercellular Communication	Colonoscopy showed an ileocecal valve polyp, florid inflammation of cecum and ascending colon and ulcerations of the terminal ileum.	18214635
Inflammation, Colorectal Neoplasms	Altered Intercellular Communication	More work is needed to determine whether C-reactive protein is a valid marker of intra-colonic inflammation, and whether such inflammation contributes to the etiology of colorectal neoplasia.	18214695
Leukoencephalopathy, Inflammation	Altered Intercellular Communication	Magnetic resonance imaging (MRI) of the brain revealed leukoencephalopathy, cerebrospinal fluid showed signs of inflammation.	18215154
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Previous studies suggest that markers of inflammation are elevated in patients with atrial fibrillation (AF).	18215601
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	However, because inflammation has been implicated in contributing to risk of both AF and coronary artery disease (CAD), which are often present in the same populations, it is important to control for confounding by the presence of CAD.	18215601
Airway structure, Asthma	Altered Intercellular Communication	Budesonide/formoterol maintenance and reliever therapy: impact on airway inflammation in asthma.	18216054
Pneumonitis	Altered Intercellular Communication	The use of exhaled breath condensate (EBC) as a tool for noninvasive assessment of lung inflammation is becoming commonplace.	18216059
Inflammation	Altered Intercellular Communication	High-sensitivity C-reactive protein (hsCRP) is an inflammation marker and potential predictor of cardiovascular events.	18216376
Inflammation, Neoplasms	Altered Intercellular Communication	Twenty-three patients had peritumoral inflammation, mimicking tumor invasion.	18216537
Inflammation	Altered Intercellular Communication	Histopathologic examination showed bamboo trichomes in the epithelial scraping without inflammation.	18216582
Inflammation	Altered Intercellular Communication	Trichomes of bamboo shoots may affect and stay in the cornea without significant inflammation because of their inert nature.	18216582
Inflammation, Keratitis	Altered Intercellular Communication	Acanthamoeba keratitis: persistent organisms without inflammation after 1 year of topical chlorhexidine.	18216589
Keratomileusis, Laser In Situ	Altered Intercellular Communication	To report a case of late-onset interface inflammation associated with wearing a cosmetic lens 18 months after laser in situ keratomileusis (LASIK).	18216591
Inflammation, Atherosclerosis	Altered Intercellular Communication	It has been established that inflammation and enhanced pro-coagulant activity are associated with the pathogenesis of atherosclerotic vascular disease.	18217146
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	In conclusion, the majority of ACS and CAD-MI patients have circulating FXIa that correlates with markers of coagulation and inflammation.	18217146
Inflammation, Dermoid Cyst, Neoplasms	Altered Intercellular Communication	However during the surgery a dermoid teratoma of the right ovary was detected so it was removed together with tumor and there were two thickenings on the greater omentum, suspicious of inflammation, whereas one grew together with the front abdominal wall.	18217476
Inflammatory, Inflammation	Altered Intercellular Communication	Lack of INF-gamma and a high cytokine presence without significant corresponding periopathogens or viruses raise a concern that inflammation and, thus, inflammatory bone destruction, is possible outside of these variables.	18218051
Inflammation, Osteopenia	Altered Intercellular Communication	Inflammation and bone loss around this same group of scalloped implants, reported by our previous study, may have been initiated by local factors, such as particular implant design features.	18218051
Keratitis	Altered Intercellular Communication	C-Jun NH2 terminal kinase (JNK) is an essential mediator of Toll-like receptor 2-induced corneal inflammation.	18218857
Corneal Stroma, Keratitis, Corneal Opacity	Altered Intercellular Communication	To determine if JNK is also important in TLR2-induced corneal inflammation in vivo, we examined JNK1(-/-) mice and pharmacological inhibitors in a murine model of TLR2-induced corneal inflammation which is characterized by neutrophil recruitment to the corneal stroma and development of corneal haze.	18218857
Keratitis	Altered Intercellular Communication	We found that corneal inflammation was significantly impaired in JNK1(-/-) mice compared with control mice, and in mice treated with the JNK inhibitor compared with vehicle control.	18218857
Keratitis	Altered Intercellular Communication	Taken together with results from HCE cells, these findings demonstrate that JNK has an essential role in TLR2-induced corneal inflammation.	18218857
Inflammation, Deposition	Altered Intercellular Communication	It has been reported that stent deployment results in acute inflammation and platelet deposition as an acute phase reaction and smooth muscle cell (SMC) proliferation as a chronic phase reaction.	18219159
Inflammation, Autoimmune Pancreatitis, Pancreaticobiliary Malunion	Altered Intercellular Communication	Autoimmune pancreatocholangitis is characterized by sclerosing inflammation of the biliary tree or pancreatic duct and can mimic pancreaticobiliary malignancy.	18219538
Inflammation, Bronchial Hyperreactivity	Altered Intercellular Communication	Asthmatic inflammation is responsible for vital features of the disease, including bronchial hyperresponsiveness (BHR).	18219765
Inflammation	Altered Intercellular Communication	At present we do not have precise markers for monitoring asthmatic inflammation.	18219765
Inflammation	Altered Intercellular Communication	C-reactive protein (CRP), a marker of systemic inflammation, seemed to be a factor which could also reflect the level of asthmatic inflammation expressed by BHR.	18219765
Inflammation, MS4A2 wt Allele	Altered Intercellular Communication	In addition, hsCRP serum concentration, after adjustment for age, atopy, body mass index, and gender, was not a significant predictor of positive histamine bronchoprovocation test results (p = 0.22, Serum hsCRP concentration is not a good marker of BHR, which is mainly dependent on asthmatic inflammation and is measured during bronchial challenge with histamine.	18219765
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	[The activity of nonspecific inflammation in hypertensive patients].	18220025
Inflammation	Altered Intercellular Communication	A positive correlation between CRP, IL-6 and BP may evidence for involvement of nonspecific inflammation in the course of EH.	18220025
Inflammation, Myocardial Infarction	Altered Intercellular Communication	A reduction in xanthine oxidase improves cardiac output, improves endothelial function, reduces myocardial infarct size, reduces inflammation, reduces myocardial oxidative stress and platelet adhesiveness.	18220728
Inflammation, Tumor necrosis, Bronchiectasis	Altered Intercellular Communication	[The association between bronchiectasis, systemic inflammation, and tumor necrosis factor alpha].	18221721
Inflammation, Bronchiectasis	Altered Intercellular Communication	The relationship between systemic inflammation and different measures of bronchiectasis severity has not been described.	18221721
Granulomatous Mastitis, Mastitis, Immunoglobulin M, Inflammatory Breast Carcinoma	Altered Intercellular Communication	Idiopathic granulomatous mastitis (IGM) is a rare, benign, chronic inflammatory condition of the breast that can mimic inflammatory breast cancer and periductal mastitis (PDM).	18222379
Communicable Diseases, Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	These findings indicate that SAA, which is an acute-phase apolipoprotein that plays important roles in infection, inflammation, and tissue repair, may contribute to the pathogenic changes to the TM in glaucoma.	18223246
Inflammation, Necrosis	Altered Intercellular Communication	Preliminary evaluation suggested chronic inflammation admixed with proliferating spindle cells and necrosis.	18223309
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Fiberoptic bronchoscopy revealed left vocal cord paralysis, bronchial mucosal inflammation and multiple anthracotic plaques.	18224512
Inflammation, Anthracosis	Altered Intercellular Communication	The thoracotomy was performed and a mediastinal lymph node showing caseating granulomatous inflammation with anthracosis and parenchymal anthracosis were detected.	18224512
Inflammation, Thrombosis	Altered Intercellular Communication	Matrix metalloproteinase-3 (MMP-3) plays a pivotal role in inflammation and thrombosis.	18225577
Malignant Neoplasms	Altered Intercellular Communication	Inflammation-related factors have recently been found to contribute to the development of malignancies.	18225577
Inflammation	Altered Intercellular Communication	Recent evidence suggests that individuals with certain personality traits are at elevated risk for chronic systemic inflammation.	18226879
Inflammation, Aggressive behavior, Inflammatory disorder, Hostility	Altered Intercellular Communication	These findings suggest that unique attributes of aggressive behavioral tendencies account for much of the variability in inflammation associated with hostility and negative emotions, raising the possibility that individuals high in aggression are at increased risk of inflammatory disease.	18226879
Inflammation, Hypoplasia, Dental caries	Altered Intercellular Communication	No statistical significant difference was found between the RG and HG subjects in terms of the presence of gingival inflammation, dental history of caries, and enamel hypoplasia.	18228044
ARCN1 gene, Inflammation	Altered Intercellular Communication	Clinical PR is unlikely to exacerbate systemic inflammation in COPD.	18229573
Paracolic	Altered Intercellular Communication	CT scan in CD patients always showed signs of severe colonic and pericolonic inflammation.	18231855
Inflammation	Altered Intercellular Communication	Conversely, UD patients often showed moderate localized signs of inflammation without complication.	18231855
Inflammation	Altered Intercellular Communication	In 65 cases, larval fragments could not be identified on aspirates, and the diagnosis of parasitic inflammation was suggested on the basis of other cytomorphological findings, which are discussed.	18232008
Inflammation, Acute Coronary Syndrome, Atherosclerosis, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	It is generally accepted that inflammation has an important role, not just in the pathogenesis of atherosclerosis, but also in initiation of acute coronary syndrome (ACS).	18232274
Inflammation, Lupus Erythematosus	Altered Intercellular Communication	Role of resistin as a marker of inflammation in systemic lupus erythematosus.	18234104
Inflammation, Kidney Diseases, Osteopenia	Altered Intercellular Communication	Although resistin measurements did not differ between patients and controls, resistin was clearly associated with general inflammation, renal disease, treatment with glucocorticosteroids, and bone loss.	18234104
Airway structure, Asthma	Altered Intercellular Communication	Aeroallergen sensitization in adult asthmatic patients from a wide geographic area has not been correlated with patients' characteristics, markers of airways inflammation, and lung function.	18234311
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Influence of electrical cardioversion on inflammation and indexes of structural remodeling, in persistent atrial fibrillation.	18234374
Inflammation, Cardiac Arrhythmia	Altered Intercellular Communication	During the development of AF, structural remodeling (besides electrical remodeling) and inflammation could play a pivotal role in perpetuation and recurrence of the arrhythmia after EC.	18234374
Communicable Diseases, Immune System Diseases, Atherosclerosis	Altered Intercellular Communication	Inflammation-induced atherosclerosis and enhanced susceptibility to infection are linked to immune dysfunction and account for an important part of mortality in hemodialysis patients.	18235144
Inflammation, Cysticercosis	Altered Intercellular Communication	[The use of systemic and intravitreous steroid in inflammation secondary to intraocular cysticercosis: case report].	18235916
acute glaucoma	Altered Intercellular Communication	The presumptive diagnosis was acute nonspecific orbital inflammation affecting the ocular bulb posterior segment together with acute glaucoma.	18235921
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Native, oxidized lipoprotein(a) and lipoprotein(a) immune complex in patients with active and inactive rheumatoid arthritis: plasma concentrations and relationship to inflammation.	18237550
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation may induce the changes of Lp(a), resulting in increased ox-Lp(a) and Lp(a)-IC, and may play an important role in atherosclerosis.	18237550
Cardiovascular Diseases	Altered Intercellular Communication	Cardiovascular disease is associated with chronic low-level inflammation, as evidenced by elevated circulating proinflammatory cytokines.	18237588
Inflammation	Altered Intercellular Communication	Experimental evidence suggests that inflammation can be suppressed under conditions of high shear stress.	18237588
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	Omega-3 polyunsaturated fatty acid in peripheral arterial disease: effect on lipid pattern, disease severity, inflammation profile, and endothelial function.	18237823
Peripheral Vascular Diseases, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Peripheral arterial disease (PAD) is strongly associated with endothelial dysfunction and inflammation, which portend a high cardiovascular risk.	18237823
Inflammation, Ichthyosis Bullosa of Siemens, physiopathological, Irritable Bowel Syndrome	Altered Intercellular Communication	Irritable bowel syndrome (IBS) has been associated with mucosal dysfunction, mild inflammation, and altered colonic bacteria.	18237869
Inflammation, Inflammatory pain	Altered Intercellular Communication	These results, in human tissue, demonstrate that iGluR mRNA and protein expression are increased during persistent inflammation and that this increased activity may be involved in mediating clinical inflammatory pain in human skin.	18238837
Tumor necrosis, Inflammation	Altered Intercellular Communication	The speed of granulation maturation, and decline in tumour necrosis factor-alpha levels indicating control of inflammation, were also more favourable with the herbal group.	18239240
Inflammation, Carcinoma	Altered Intercellular Communication	Intra-operative frozen section examination was conducted in three patients: chronic inflammation without evidence of carcinoma was visualised in each.	18239243
Inflammation, Endothelial dysfunction, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation has been found to play a role in the etiology of cardiovascular disease as well as provoke endothelial dysfunction.	18239561
Hepatosplenomegaly, Inflammation, Histiocytosis haematophagic, Lymphohistiocytosis, Hemophagocytic, Blood Coagulation Disorders, Prolonged fever, Cytopenia	Altered Intercellular Communication	The clinical syndromes of hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS) are both characterized by dysregulated inflammation with prolonged fever, hepatosplenomegaly, coagulopathy, hematologic cytopenias, and evidence of hemophagocytosis in the bone marrow or liver.	18240215
Necrotizing granulomatous inflammation, Deposition	Altered Intercellular Communication	Granulomatous vascular inflammation was found in 6 specimens and was associated in 4 cases with vascular deposits of beta-amyloid peptide.	18240248
Hormone abnormality, Azoospermia	Altered Intercellular Communication	Hormonal abnormalities were detected in 22% oligospermic, 40.7% severe oligospermic, and 42.7% azoospermic subjects.	18240705
Inflammation, Nephrolithiasis	Altered Intercellular Communication	To investigate the intrarenal mRNA expression of monocyte chemoattractant protein-1 (MCP-1) and interleukin-6 (IL-6) in patients with nephrolithiasis, and to evaluate whether their expression is associated with renal function, as oxidative stress and inflammation are involved in the pathogenesis of nephrolithiasis.	18241247
Nephritis, Nephrolithiasis	Altered Intercellular Communication	Nephrolithiasis was associated with low-grade intrarenal inflammation.	18241247
Vitreoretinal Area, Inflammation, Pain, Postoperative, Infectious Arteritis	Altered Intercellular Communication	Although infectious scleritis is an uncommon complication after vitreoretinal surgery, it should be a considered cause in patients with persistent postoperative pain and inflammation.	18241830
Inflammation, Temporomandibular Joint	Altered Intercellular Communication	After the surgeries chemotherapy could continue without signs of inflammation in the temporomandibular joint or mastoid region.	18242031
Mucous Membrane, Inflammation	Altered Intercellular Communication	Small-bowel mucosal injury and inflammation were assessed by video capsule endoscopy, the lactulose:L-rhamnose permeability assessment, and the fecal calprotectin test.	18242145
Gastritis	Altered Intercellular Communication	Because H pylori induces T-cell dependent gastric inflammation in adults and T regulatory (Treg) cells suppress T-cell-dependent pathology, we evaluated gastric histopathology and Treg cell responses in H pylori-infected children and adults.	18242215
Gastritis	Altered Intercellular Communication	Coincident with reduced gastric inflammation, the number of Treg cells and levels of Treg cytokines (transforming growth factor [TGF]-beta1 and interleukin-10) were increased markedly in the gastric mucosa of H pylori-infected children compared with that of infected adults (P < .03 and < .05, respectively).	18242215
Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	Gastric pathology is reduced and local Treg cell responses are increased in H pylori-infected children compared with infected adults, suggesting that gastric Treg cell responses down-regulate the inflammation and ulceration induced by H pylori in children.	18242215
Inflammation, myocardial injury	Altered Intercellular Communication	Finally, the hybrid procedure showed significantly reduced transcardiac gradients of markers of coagulation, myocardial injury, and inflammation and a trend toward significant improvement in target-vessel patency.	18242270
Inflammation, myocardial injury	Altered Intercellular Communication	Perhaps because of reduced myocardial injury, inflammation, and activation of coagulation, patients undergoing the hybrid procedure had better perioperative outcomes and satisfaction, with excellent patency at 1 year's follow-up.	18242270
vascular inflammations, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	However, the association of a haplotype containing the rs755622C allele, which has been reported before to increase the susceptibility for various other proinflammatory conditions, with CHD points towards a role for MIF in local vascular inflammation and atherogenesis.	18242614
Fungal sinusitis, Rhinorrhea, Neoplasms, Fibrous Dysplasia, Polyp in nasopharynx	Altered Intercellular Communication	The pathology spectrum was rather wide and included 26 (65%) inflammatory conditions (acute/chronic sphenoiditis, mucoceles, and fungal sinusitis), 7 (17.5%) neoplasms and 7 (17.5%) miscellaneous conditions (cerebrospinal fluid (CSF) rhinorrhea, sphenochoanal polyp, and fibrous dysplasia).	18242904
Inflammation	Altered Intercellular Communication	Genetic and environmental influences on systemic markers of inflammation in middle-aged male twins.	18243214
Inflammation	Altered Intercellular Communication	After adjusting for covariates known to influence inflammation levels, heritability estimates were slightly decreased but the overall results remained similar.	18243214
Inflammation	Altered Intercellular Communication	Furthermore, almost 50% of the shared variance among these biomarkers is due to a common genetic factor which likely plays a key role in the regulation of inflammation.	18243214
Granulomatous inflammation	Altered Intercellular Communication	Definite cases of CBD required (1) an abnormal beryllium lymphocyte proliferation test in blood or bronchoalveolar lavage and (2) biopsy evidence of granulomatous inflammation.	18244954
Inflammation	Altered Intercellular Communication	Inflammation and rate of cognitive change in high-functioning older adults.	18245760
Inflammation, Impaired cognition	Altered Intercellular Communication	Although high levels of inflammation are associated with incident cognitive impairment, these results do not generalize to the full range of cognitive changes, where the role of inflammation appears to be marginal.	18245760
Pterygium Of Conjunctiva And Cornea, Conjunctivitis	Altered Intercellular Communication	Role of conjunctival inflammation in surgical outcome after amniotic membrane transplantation with or without fibrin glue for pterygium.	18245968
Pyogenic granuloma, Pterygium Of Conjunctiva And Cornea, Conjunctivitis	Altered Intercellular Communication	Main outcome measures included development of conjunctival inflammation, pyogenic granuloma, and pterygium recurrence after surgery.	18245968
Conjunctivitis	Altered Intercellular Communication	Conjunctival inflammation around the surgical site was noted in the remaining 11 (40.7%) eyes and was significantly more common in eyes with sutures than those with fibrin glue (61.5% vs. 21.4%, respectively; P = 0.05).	18245968
Pterygium Of Conjunctiva And Cornea, Conjunctivitis	Altered Intercellular Communication	Host conjunctival inflammation is still common after intraoperative application of mitomycin C and amniotic membrane transplantation, especially when sutures are used in pterygium surgery.	18245968
Inflammation	Altered Intercellular Communication	If left untreated, persistent inflammation may lead to a poor surgical outcome.	18245968
Keratitis	Altered Intercellular Communication	Slit-lamp examination showed a large corneal infiltrate surrounded by marked corneal inflammation.	18245979
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	This study confirms the involvement of inflammation in ALS and the need to develop surrogate markers to check the progression of this disease.	18246426
Inflammation	Altered Intercellular Communication	We demonstrate that IgM-enriched Igs are superior to IgG alone in attenuating LPS-induced leukocytic inflammation and microcirculatory dysfunction.	18246604
Inflammation, Damage, Metabolic Syndrome X, MS gene	Altered Intercellular Communication	This analysis compares the performance of 7 different diagnostic criteria of metabolic syndrome (MS) with regard to the prevalence of the syndrome, the characteristics of subjects with a positive diagnosis, and the ability to correctly identify individuals at high calculated cardiovascular (CV) risk or with signs of systemic inflammation or early organ damage.	18249207
Inflammation, square decimeter, Metabolic Syndrome X, Atherosclerosis, MS gene	Altered Intercellular Communication	We hypothesize that metabolic syndrome (MS) and low-grade systemic inflammation modify the extent of atherosclerosis in DM2.	18249307
Inflammation	Altered Intercellular Communication	Patients with four MS criteria and inflammation (CRP >or=3 mg/L) are predicted to have a 0.21 mm thicker IMT than those without.	18249307
Inflammation, square decimeter	Altered Intercellular Communication	MS and low-grade chronic inflammation have an independent impact on vascular phenotype including IMT in DM2.	18249307
Autoimmune Diseases, Inflammation, Refractory anemias	Altered Intercellular Communication	Ligation of DCIR, or lack thereof, could contribute to the chronic inflammation characterising autoimmune diseases such as RA.	18250113
Inflammation, Fibrosis Assessment, Retroperitoneal fibrosis, Retroperitoneal Space	Altered Intercellular Communication	Idiopathic retroperitoneal fibrosis is an uncommon disease characterized by periaortic inflammation with gradual fibrosis and distortion of retroperitoneal structures such as the ureter.	18250993
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We suggest that FDG PET may play a useful adjunct to anatomic imaging and serum inflammatory markers in assessing the severity of inflammation in retroperitoneal fibrosis, and in assessing the likelihood of response to immunosuppressive therapy.	18250993
Inflammation, Idiopathic Inflammatory Myopathies	Altered Intercellular Communication	To determine if a multiplex immunoassay for markers of inflammation in muscle homogenates correlates with a diagnosis of IIM.	18251582
Blindness, Inflammation, Blood Clot	Altered Intercellular Communication	Total obstruction of the arterial lumen by a thrombus, intensity of the inflammatory cells infiltration and inflammation of small vessels, nerves and veins surrounding the temporal artery were not associated with blindness.	18252763
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Our findings suggest that higher circulating adiponectin levels may mitigate against adipose-related inflammation, insulin resistance and MetS as much in lean as obese persons.	18253163
Inflammation, Laryngitis	Altered Intercellular Communication	Chronic laryngitis is a lingering inflammation of the laryngeal mucosa, caused by specific aetiology and often irritative factors.	18254283
Orchitis	Altered Intercellular Communication	Because of its seriousness, SA should be evocated in front of any articular inflammation occurring in elderly.	18254307
Inflammation, Edema	Altered Intercellular Communication	We consider that nebulized Pulmicort respimat after FESS can relieve the acute inflammation and oedema, it can also reduce the complication of the surgery.	18254326
Communicable Diseases, Inflammation, Neoplasms, Blood Coagulation Disorders	Altered Intercellular Communication	Most cases are caused by abnormal coagulopathy, infection, inflammation or tumor invasion.	18254578
vascular inflammations	Altered Intercellular Communication	In this study, evidence of decreased antioxidant status was determined in CMP patients together with vascular inflammation.	18254715
Inflammation, Anterior uveitis, Herpetic whitlow, Uveitis	Altered Intercellular Communication	CMV anterior uveitis is not uncommon in our immunocompetent patients and it may present as a recurrent acute or chronic inflammation, resembling PSS, herpetic anterior uveitis, or FHI.	18255045
Bipolar Disorder, Coronary Artery Disease, Hostility	Altered Intercellular Communication	Our findings suggest that depressive symptoms may moderate the hostility-inflammation relationship such that hostility may augment inflammatory processes relevant to coronary artery disease only in the presence of depressive symptoms.	18256345
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Oxidative stress and inflammation are associated with adiposity in moderate to severe CKD.	18256365
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Adiposity contributes to inflammation and oxidative stress in the general population, but this association has not been examined in the chronic kidney disease (CKD) population.	18256365
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We conclude that increased adiposity may amplify the oxidative stress and inflammation that accompany moderate to severe CKD.	18256365
Fever, CTCAE, Stenosis Morphology, Occluded, Anemia, Anorexia, Vasculitis	Altered Intercellular Communication	TA has three phases: 1. weakness, fever, anemia, loss of appetite: 2. inflammation of blood vessels; 3. symptoms of stenosis and occlusive lesions.	18257210
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Granulocyte and monocyte adsorption apheresis (GCAP) has recently shown remarkable effects on ulcerative colitis, which is characterized by inflammation and neutrophil infiltration.	18257807
Inflammation, atherosclerotic, Atherosclerosis	Altered Intercellular Communication	Low HDL-cholesterol concentrations are associated with increased cardiovascular risk and recent evidences suggest that HDL may aggravate the atherosclerotic process promoting inflammation: HDL are anti-inflammatory in the absence of inflammation but can become proinflammatory in the presence of atherosclerosis.	18258237
Inflammation, Hypercholesterolemia, Diabetes Mellitus, Coronary Artery Disease, Obesity, Hypertension, CTCAE	Altered Intercellular Communication	male gender, older age, obesity, hypertension, diabetes, smoking, family history of coronary artery disease, hypercholesterolemia), as well as levels of two markers of inflammation (C-reactive protein and fibrinogen).	18258237
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	These findings further suggest a synergistic role of low-HDL and inflammation on the atherosclerotic disease progression from subclinical lesions to clinical events.	18258237
Inflammation, Fatigue	Altered Intercellular Communication	Peritoneal inflammation and fatigue experiences following colorectal surgery: a pilot study.	18258374
Inflammation, Fatigue	Altered Intercellular Communication	The effect of post-surgical inflammation, as indicated by peritoneal cytokines and neopterin, was assessed on the duration and characteristics of post-surgical fatigue (PSF) experiences.	18258374
Inflammation, Fatigue	Altered Intercellular Communication	Locally occurring inflammatory responses may influence reports of fatigue following major surgery in a sustained manner, and, as a consequence, reducing inflammation may be effective in reducing PSF.	18258374
Necrotizing inflammation	Altered Intercellular Communication	On emergency laparotomy a perforated processus vermiformis had been removed, displaying gangrenous inflammation.	18258564
Inflammation, Atherosclerosis	Altered Intercellular Communication	Many gene products involved in oxidation and inflammation are implicated in the pathogenesis of atherosclerosis.	18258817
Inflammation, Dental Plaque, Rupture	Altered Intercellular Communication	This effect, in turn, might contribute to plaque stabilization by inhibiting the activation of nuclear factor kappaB-dependent inflammation, responsible for plaque rupture.	18259030
Refractory anemias, Inflammation, Rheumatoid Arthritis, Osteopenia	Altered Intercellular Communication	To investigate the effects of vitamin K2 (Vit K2) alone or in combination with etidronate and risedronate on bone loss, osteoclast induction, and inflammation in patients with rheumatoid arthritis (RA).	18260178
Inflammation	Altered Intercellular Communication	[Bacterial flora in paranasal sinuses of the chronic inflammation].	18260259
Inflammation, teratologic	Altered Intercellular Communication	There were no anomalies in any of the cases, and they were divided into two groups: a group with inflammation of middle ear and a group without inflammation.	18260300
Inflammation, Nasal Cavity and Paranasal Sinus Carcinoma	Altered Intercellular Communication	However, CRSwNP patients have more severe inflammation in nasal and sinus cavity, which is related to eosinophilic inflammation in local mucosa.	18260371
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	SMI may be caused by inflammation and endothelial dysfunction.	18261275
Refractory anemias, Inflammation, Rupture	Altered Intercellular Communication	In 50% of patients with RA, however, the disease also involves inflammation of the synovial tissue surrounding the tendons, which is associated with multiple ruptures and poor prognosis for long-term hand function.	18261665
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	Systemic markers of inflammation (C-reactive protein, white blood cell count, fibrinogen) were also associated with PVD, and were also significantly associated with PAL.	18262191
Peripheral Vascular Diseases, Inflammation, Periodontal Diseases	Altered Intercellular Communication	Inflammation may be one possible pathway to link PVD with periodontal disease.	18262191
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Low-grade inflammation is a common feature of chronic kidney disease (CKD) and persistent systemic inflammation is thought to be a strong predictor of cardiovascular events.	18262432
HD Term Type, Inflammation	Altered Intercellular Communication	Inflammation plays a role in determining the serum albumin levels in haemodialysis patients (HD) independently of the nutritional status.	18262432
Cessation of life, Inflammation	Altered Intercellular Communication	The authors' findings from this community-based prospective cohort study suggest that the selected SNPs are not associated with overall or cause-specific death, although CRP genotypes may be associated with systemic inflammation.	18263601
palladium, Neurogenic Inflammation	Altered Intercellular Communication	On the basis of a peculiar case that appeared soon after multiple dental fillings with a mercury-containing amalgam, we proposed that neurogenic inflammation could play a role in the pathogenesis of PD.	18264633
Inflammation, Disease	Altered Intercellular Communication	According to the new findings provided by clinical and basic research, neurogenic inflammation has a relevant part in the pathogenesis of many cutaneous diseases.	18264633
Inflammation	Altered Intercellular Communication	A long course of appropriate antibiotic administration finally resolved the inflammation and resulted in a good clinical outcome without surgical drainage.	18264664
Weight Gain, Malnutrition	Altered Intercellular Communication	Our objective was to investigate the correlations of interdialytic weight gain (IDWG) with the Malnutrition Inflammation Score (MIS) and other nutritional markers, especially when age difference is considered.	18267214
Inflammation, Familial Colorectal Cancer Type X	Altered Intercellular Communication	Low-penetrance alleles of genes in many biological pathways, such as DNA repair, metabolism, inflammation, cell cycle, apoptosis, and Wnt signaling, may influence the risk of nonfamilial colorectal cancer.	18268114
Inflammation, Neurologic Dysfunction	Altered Intercellular Communication	In ONDs, the highest CSF osteopontin levels are seen in patients with rapidly progressive neurological dysfunction or widespread inflammation of the central nervous system.	18268193
Pericardial effusion, Inflammation, Tuberculosis, Mycoses, Neoplastic disease, Virus Diseases	Altered Intercellular Communication	The following diagnoses for the pericardial effusions were established: nonspecific inflammation, 50 cases (54.94%); neoplastic disorders, 22 cases (24.17%); tuberculous, 11 cases (12.08%); bacterial inflammatory process, 3 cases (3.29%); chylopericardial, 2 cases (2.19%); fungal infection, 2 cases (2.19%); and viral infection, 1 case (1.09%).	18270145
Tumor necrosis, Atherosclerosis	Altered Intercellular Communication	Tumor necrosis factor-alpha (TNF-alpha) plays an important role in forming atherosclerosis based on chronic inflammatory condition in vivo and animal models.	18270431
Inflammation, Amyloidosis	Altered Intercellular Communication	Histological examination demonstrated localized amyloidosis, secondary to inflammation.	18271428
Keratitis	Altered Intercellular Communication	Treatment with intensive topical steroids led to resolution of his limbal and corneal inflammation, leaving the deposition unchanged.	18271782
Communicable Diseases, Inflammation, Inflammatory disorder	Altered Intercellular Communication	C-reactive protein (CRP) has been used for the evaluation of inflammation in patients with infection and inflammatory diseases.	18271801
Inflammation, Myocardial Ischemia	Altered Intercellular Communication	Recently, high-sensitivity CRP has been shown to reflect mild and/or moderate inflammation for the prognosis of ischemic heart disease.	18271801
Inflammation, Sample Size Calculation	Altered Intercellular Communication	High-sensitivity CRP was measured for the evaluation of mild and/or moderate inflammation in SSc.	18271801
Inflammation, Bone Marrow Suppression, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	Inadequate erythropoietin production, reduced life span of erythrocytes in uremic serum, bone marrow suppression by uremic toxins, chronic inflammation, and contaminants in the water treatment unit are recognized etiological causes of anemia in chronic kidney disease patients.	18271848
Inflammation, Gastroenteritis, Liver Dysfunction, Air Embolism, Dehydration, Kidney Failure	Altered Intercellular Communication	A laboratory and radiographic examination indicated dehydration, inflammation, liver dysfunction, renal failure, necrotizing gastroenteritis, and multiple air embolisms.	18272134
Inflammation	Altered Intercellular Communication	ORO is distinctly uncommon without sinonasal inflammation or previous surgery.	18272552
Myositis	Altered Intercellular Communication	At baseline, two completers had signs of muscle inflammation by MRI, and five at follow-up.	18272672
Granuloma, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	LPS diagnosis was confirmed by intra-LPS biopsy of nodules and histological examination of specimens: epithelioid granulomas with central caseous necrosis in five patients (83.3%) and a non-caseating granulomatous inflammation in the last one.	18275578
Refractory anemias, Inflammation	Altered Intercellular Communication	In sections from early patients with RA taken before and under antirheumatic treatment, the degree of inflammation and activation of the BMP pathway were quantified.	18276742
Inflammation	Altered Intercellular Communication	Antirheumatic treatment effectively downregulates synovial inflammation, but BMP activation in the synovium does persist albeit reduced.	18276742
Polymyositis, Dysferlin, Myositis	Altered Intercellular Communication	Muscle inflammation is often present in dysferlin deficiency, and patients are frequently misdiagnosed as having polymyositis.	18276788
Inflammation, Atherosclerosis	Altered Intercellular Communication	Cysteinyl leukotrienes are involved in inflammation and possibly in early carotid atherosclerosis.	18276912
Inflammation	Altered Intercellular Communication	IgG4-related diseases are characterized by high serum IgG4 concentrations, sclerosing inflammation with numerous IgG4-positive plasma cells, and steroid sensitivity irrespective of their organs of origin.	18277032
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Effect of infliximab on local and systemic inflammation in chronic obstructive pulmonary disease: a pilot study.	18277064
ARCN1 gene, Inflammation, Tumor necrosis, Chronic Obstructive Airway Disease, Cachexia	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) with cachexia is characterized by inflammation reflected by increased levels of tumor necrosis factor-alpha (TNF-alpha).	18277064
ARCN1 gene, Inflammation, Cachexia	Altered Intercellular Communication	In this study, infliximab, an anti-TNF-alpha antibody, was evaluated for its effects on systemic (plasma) and local (exhaled breath condensate, EBC) inflammation in cachectic patients with COPD.	18277064
ARCN1 gene, Inflammation, Cachexia	Altered Intercellular Communication	In this small study, infliximab did not produce an observable decrease in local inflammation in cachectic patients with COPD and had minor effects on systemic inflammation.	18277064
Inflammation, Prostate Cancer Outcomes Study, Dyslipidemias, Endothelial dysfunction, Hypertension, CTCAE	Altered Intercellular Communication	Several cardiovascular risk factors are often related to metabolic alterations, such as dyslipidemia, hypertension, endothelial dysfunction, low grade chronic inflammation, that are present even at early age in PCOS women.	18277351
Compact Disk Interactive, AVP gene	Altered Intercellular Communication	Hormonal evaluations demonstrated central diabetes insipidus (CDI), with normal anterior pituitary function.	18277371
Steatohepatitis, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Seven of the 23 patients consented to undergo posttreatment liver biopsy, which showed improvement of hepatic steatosis and fibrosis, hepatocyte ballooning, and lobular inflammation in 6 patients.	18277895
Airway structure, Asthma	Altered Intercellular Communication	HsCRP levels: measurement of airway inflammation in asthmatic children.	18279198
Vascular Diseases, Homocysteine measurement, Inflammation	Altered Intercellular Communication	Elevated plasma homocysteine is a risk factor for vascular diseases, possibly due to homocysteine-mediated increase in oxidative stress and inflammation.	18280483
Inflammation, Subarachnoid Hemorrhage, Aneurysm, Ruptured	Altered Intercellular Communication	We show that elevated YKL-40 levels are not correlated with the severity of subarachnoid haemorrhage and cannot be used as a serological marker of inflammation in patients with an aneurysm rupture.	18280741
PALATAL INFLAMMATION	Altered Intercellular Communication	Patients treated with M. alternifolia mixed with Coe-Comfort showed a significant decrease in palatal inflammation compared with those treated with Coe Comfort (P = .001).	18280967
Osteogenesis, Inflammation, Hyperplasia, With intensity	Altered Intercellular Communication	Unexposed diseased bone was characterized by T1 hypointensity and T2 and IR hyperintensity, which suggests high water content and inflammation, associated with hypercellularity, osteogenesis, and hypervascularity (osteomyelitic pattern).	18280968
Neuronal loss in central nervous system, physiopathological	Altered Intercellular Communication	The pathological processes lead to neuronal loss, synaptic dysfunction and inappropriate activity of neurotransmitters.	18283248
Airway structure, ARCN1 gene, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Sputum induction (SI) is a safe and effective technique to study airway inflammation in asthma and chronic obstructive pulmonary disease (COPD).	18283650
Parkinson Disease	Altered Intercellular Communication	Inflammation-related genes and the risk of Parkinson's disease: a multilocus approach.	18284424
Inflammation, Hepatitis	Altered Intercellular Communication	The severity of parenchymal inflammation and of interface hepatitis was semiquantitatively graded on a haematoxylin and eosin stained paraffin sections.	18284441
Craniosynostosis	Altered Intercellular Communication	This retrospective study showed that bacterial biofilms and fungus were correlated with the persistence of postoperative symptoms and mucosal inflammation after sinus surgery for CRS.	18284851
Inflammation, Craniosynostosis	Altered Intercellular Communication	This provides evidence that biofilms indeed may play an active role in perpetuating inflammation in CRS patients and may explain the recurrent and resistant nature of this disease.	18284851
Inflammation, IL13 gene	Altered Intercellular Communication	Although the procedure has been reported to be safe and effective, we tested the hypothesis that the prognosis might deteriorate with time in allergic rhinitis patients as identified by a positive allergen test in patients who have a persistent regional inflammation of the nose.	18284854
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Fungus-driven inflammation is proposed to play an important role in the pathogenesis of chronic rhinosinusitis (CRS).	18284860
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	The cornerstone of high CVD incidence in ESRD patients is endothelial dysfunction which results from inflammation, oxidative stress and insulin resistance.	18285698
Inflammation, Fibrous, Thickened	Altered Intercellular Communication	Principal histological FPS findings include dermal thickening, inflammation and thickening of the subcutaneous fat tissue, fibrous thickening of the fascia and inflammation of the adjacent muscle.	18286355
Communicable Diseases, Inflammation	Altered Intercellular Communication	Feeling isolated could accelerate aging, affecting inflammation and infection at the cellular level.	18286731
Inflammation, Cutaneous Precancerous Condition	Altered Intercellular Communication	Genetic polymorphisms in mediators of inflammation and gastric precancerous lesions.	18287876
Inflammation, Helicobacter pylori, Carcinogenesis	Altered Intercellular Communication	Chronic inflammation induced by Helicobacter pylori is a key process in gastric carcinogenesis.	18287876
Inflammation, precancerous lesions	Altered Intercellular Communication	We hypothesized that genetic polymorphisms in important mediators of H. pylori-induced inflammation may influence the risk of developing various grades of precancerous lesions.	18287876
Inflammation, Necrosis	Altered Intercellular Communication	This revealed inflammation and necrosis of the ileocecal fold of Treves and a normal-appearing appendix.	18287997
Inflammation	Altered Intercellular Communication	chronic inflammation contributes significantly to the morbidity and mortality of chronic hemodialysis patients.	18288267
Inflammation	Altered Intercellular Communication	A recent research has shown that adipokines were associated with inflammation in these patients.	18288267
Inflammation	Altered Intercellular Communication	the presence of underlying disease, advanced age, and markers of chronic inflammation is strongly related to survival rate in long-term hemodialysis patients.	18288267
Inflammation, Neoplasms	Altered Intercellular Communication	Recently, chronic inflammation has been accepted as a crucial factor in the pathogenesis of neoplasia.	18288720
Inflammation	Altered Intercellular Communication	The chronic inflammation provides dynamic setting for oxidative stress and formation of free radicals.	18288720
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Ulcerative colitis (UC) is characterized by chronic recurrent mucosal inflammation.	18289203
Inflammation, Carcinogenesis, Ulcerative Colitis	Altered Intercellular Communication	Complete elucidation of the mechanism of UC-CRC carcinogenesis will require investigation of other genes involved in modulating inflammation, but our results suggest that some UC patients may have additional genetic predispositions toward developing UC-CRC.	18289203
Inflammation, Carcinogenesis	Altered Intercellular Communication	Regenerating gene (REG), an epithelial growth factor, has been reported to link mucosal inflammation and subsequent carcinogenesis in the gastrointestinal tract.	18289358
Inflammation	Altered Intercellular Communication	These results suggest that BN/GRP and SP may modulate inflammation and vascular events, and possibly healing processes in the synovium.	18289674
Inflammation	Altered Intercellular Communication	Increases in the number and activity of interstitial mast cells and their degranulation and the symptoms of chronic immune inflammation were revealed.	18290377
Inflammation, Comorbidity	Altered Intercellular Communication	In addition, the concentration of PTX-3 was associated with inflammation markers and comorbidity score.	18292098
Inflammation	Altered Intercellular Communication	Increased serum AAT levels in PEX may explain the role of inflammation in this group of patients.	18293186
Inflammation, Hepatobiliary Disorder, Fibrosis Assessment	Altered Intercellular Communication	Correlation between liver fibrosis and inflammation in patients transplanted for HCV liver disease.	18294164
Fibrosis, Liver, Necrosis with inflammation	Altered Intercellular Communication	We evaluate the relationship between progression of liver fibrosis and histological necro-inflammation in HCV recipients, according to age of transplant.	18294164
Fibrosis Assessment, Necrosis with inflammation	Altered Intercellular Communication	Grading (necro-inflammation) and staging (fibrosis) scores were evaluated in liver biopsies at 1, 2 and 3 years from LT (Ishak classification).	18294164
Fibrosis Assessment, Necrosis with inflammation	Altered Intercellular Communication	In conclusion in HCV-LT patients (1) liver fibrosis is strictly associated to histological necro-inflammation; (2) the proportion of this relationship has been changing in recent years since newer LT patients, show an increased amount of fibrosis in comparison with the older ones, for similar grading score.	18294164
Inflammation, Aortitis, Necrosis	Altered Intercellular Communication	The second group of aortitis was designated non-NA (NNA), characterized by the absence of necrosis, with diffuse medial inflammation.	18294676
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	No reliable serum markers for liver inflammation, apoptosis and fibrosis have been established yet, although a large number have been evaluated.	18294939
Inflammation, Diplopia, Reye Syndrome, Headache, Ear discharge	Altered Intercellular Communication	The syndrome of constant otorrhea, headache, and diplopia, which is attributed to inflammation of the petrous apex, is known as Gradenigo's syndrome.	18296009
Inflammation, ME1 gene	Altered Intercellular Communication	In patients with AMI, MeS is associated with systemic inflammation and is an important predictor for MACE, which suggests the need for early identification and medical intervention for secondary prevention of MeS.	18296838
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Evaluation of oxidative stress and inflammation in obese adults with metabolic syndrome.	18298345
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Oxidative stress and inflammation markers were significantly elevated in the obese subjects, especially in those exhibiting metabolic syndrome.	18298345
Inflammation, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	High levels of free radicals together with low antioxidant capacity detected in obese adults indicate elevated oxidative stress, which is--together with systemic inflammation--further potentiated in the case of obese patients with metabolic syndrome.	18298345
Multiple Organ Failure, Inflammation, Observation Method - Coagulation, Respiratory Failure	Altered Intercellular Communication	Circulating levels of KL-6/MUC1 were measured during diagnosis and serially measured during the clinical course along with indices of respiratory failure, inflammation, coagulation and fibrinolysis and multiple organ dysfunction.	18298483
Granulomatous inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Clinical implications of granulomatous inflammation detected by endobronchial ultrasound transbronchial needle aspiration in patients with suspected cancer recurrence in the mediastinum.	18298864
Granulomatous inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Granulomatous inflammation has been previously reported in association with cancer.	18298864
Mediastinal lymphadenopathy, Granulomatous inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The identification of granulomatous inflammation by EBUS-TBNA and the clinical implications of such detection in a series of patients with previously treated cancer and new mediastinal lymphadenopathy has not previously been performed.	18298864
Maxillary Sinusitis, Inflammation	Altered Intercellular Communication	All patients had maxillary sinusitis, and 2 also had an inflammation of other paranasal sinuses.	18299227
Inflammation, Obesity	Altered Intercellular Communication	Serum amyloid A (SAA) is a novel link between increased adipose tissue mass and low-grade inflammation in obesity.	18299466
Airway structure	Altered Intercellular Communication	Previous reports indicate that inhaled corticosteroids attenuate airway inflammation.	18299653
Inflammation, Chronic sinusitis	Altered Intercellular Communication	Local IgE and inflammation in chronic rhinosinusitis of asthmatics and non-asthmatics.	18299868
Fibrosis Assessment, Chronic inflammation	Altered Intercellular Communication	Histopathological studies revealed herniated appendiceal mucosa through the muscular layer associated with chronic inflammation and marked fibrosis.	18300360
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	The aortic root was also involved with aortic valvulitis, showing severe mixed acute and chronic inflammation of various stages.	18300812
Inflammatory abnormality of the eye, Uveitis, Dystonia, Dopa-Responsive, due to Sepiapterin Reductase Deficiency	Altered Intercellular Communication	Retrospective, interventional, case study of patients with uveitis with controlled ocular inflammation who underwent drainage of a chronic SRD at the Cole Eye Institute (1998-2006).	18301034
Inflammation, Uveitis, Dystonia, Dopa-Responsive, due to Sepiapterin Reductase Deficiency	Altered Intercellular Communication	Select patients with uveitis with a SRD whose subretinal fluid fails to resorb after medical therapy and resolution of inflammation can achieve long-term retinal reattachment by surgical management.	18301034
Inflammation	Altered Intercellular Communication	Cox-2 is induced in numerous processes such as cellular growth, differentiation, inflammation and tumorogenesis.	18301460
Scheuermanns Disease	Altered Intercellular Communication	hormonal), which may play more crucial role in Scheuermann's disease pathogenesis.	18301929
Inflammation, Anemia	Altered Intercellular Communication	Laboratory findings revealed a chronic inflammation and an anemia of iron malabsorption.	18302096
Pancreatitis, Diabetes Mellitus	Altered Intercellular Communication	Type 1 diabetes is preceded by a long, protracted period of pancreatic islet inflammation by autoreactive lymphocytes.	18302224
Inflammation, Hyperglycemia	Altered Intercellular Communication	Noninvasive imaging of islet inflammation prior to the onset of hyperglycemia might have diagnostic and therapeutic implications, but this is not currently possible.	18302224
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Antigen/MHC-coupled nanoparticles represent a promising new avenue for noninvasive imaging of lymphocyte inflammation in organ-specific autoimmunity and transplantation.	18302224
Inflammation	Altered Intercellular Communication	Paraphimosis is an acute condition characterized by all the signs of inflammation.	18302866
Inflammation, Congenital Abnormality, Traumatic injury, Hydrophthalmos, Glaucoma, CTCAE	Altered Intercellular Communication	Conditions such as inflammation or trauma can contribute to elevated intraocular pressure in secondary glaucoma, whereas congenital abnormalities of the trabecular meshwork development can result in infantile glaucoma.	18302954
Inflammation	Altered Intercellular Communication	Biomarkers of inflammation predict both vascular and non-vascular mortality in older men.	18303034
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	The infiltrate within the group of eyes with systemic autoimmune disease suggests that the inflammation may be driven by B cells.	18303163
Encrusted cystitis	Altered Intercellular Communication	Encrusted cystitis is a rare chronic inflammatory condition of the bladder.	18304404
Inflammation, Prostatic Intraepithelial Neoplasias, Prostate carcinoma	Altered Intercellular Communication	For patients diagnosed with prostate carcinoma, there was no significant difference in age, incidence, grade of cancerous cells, stage of the disease, incidence of inflammation of prostatic tissues or prostatic intraepithelial neoplasia (PIN) related to elevated PSA between the groups (All P>0.05).	18304458
Inflammation, Crohn Disease	Altered Intercellular Communication	Reduced alpha-defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn's disease.	18305068
Inflammation, Crohn Disease	Altered Intercellular Communication	Reduction in alpha-defensin expression is independent of NOD2 status and is due to loss of surface epithelium as a consequence of inflammatory changes rather than being the inciting event prior to inflammation in ileal Crohn's disease.	18305068
Seizures, Inflammation, Meningitis	Altered Intercellular Communication	Seizures are associated with severe CNS and systemic inflammation, structural CNS lesions, pneumococcal meningitis, and predisposing conditions.	18305232
Pulmonary Edema, CTCAE, Pneumonitis	Altered Intercellular Communication	Elevated concentrations of the proinflammatory cytokines, interleukin (IL)-6 and IL-8, in both plasma and the pulmonary edema fluid, suggested a possible role of systemic and pulmonary inflammation in the development of this acute pulmonary capillary leak.	18306021
Inflammation, Cholangiocarcinoma	Altered Intercellular Communication	Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.	18306229
Inflammation	Altered Intercellular Communication	Chronic inflammation plays a critical role in oncogenesis in various human organs.	18306229
Cholangiocarcinoma, Cholangitis	Altered Intercellular Communication	The proinflammatory cytokine-induced aberrant production of AID might link bile duct inflammation to an enhanced genetic susceptibility to mutagenesis, leading to cholangiocarcinogenesis.	18306229
Inflammation, Liver carcinoma, Hepatitis B, FAM126A gene	Altered Intercellular Communication	Besides genomic integration of hepatitis B viral particles, persistent chronic inflammation is postulated to be important initiating factor in viral related hepatocellular carcinoma (HCC).	18306534
Inflammation, Carcinogenesis, Infection, FAM126A gene	Altered Intercellular Communication	higher incidence of inflammatory grading and enzyme level in alone HBcAg and dual HBcAg and HCV positivity in HCC group would suggest significant role of ongoing persistent chronic inflammation and actively replicating HBV and HCV infections in carcinogenesis.	18306534
ARCN1 gene, Inflammation	Altered Intercellular Communication	In conclusion, circulating levels of VEGF and markers of systemic inflammation are up-regulated in patients with acute exacerbated COPD and decrease after recovery from the exacerbation.	18307413
allergic inflammation	Altered Intercellular Communication	However, little is known about whether neonatal BCG treatment could inhibit allergic inflammation by regulating allergen-specific T-cell response in aged mice.	18307575
Airway structure	Altered Intercellular Communication	Their airway inflammation and allergen-specific T-cell responses were characterized.	18307575
Inflammation, IGA Glomerulonephritis, Glomerulonephritis	Altered Intercellular Communication	Renal biopsy revealed crescentic glomerulonephritis in 24 cases, focal segmental glomerulonephritis in 8 cases, vascular fibrinoid necrosis with inflammation in 7 cases, intimal thickening of arterioles in 24 cases, interstitial inflammatory cells, including neutrophil infiltration (21 cases), in 29 cases.	18307878
Inflammation, Gingival Overgrowth	Altered Intercellular Communication	The presence of gingival inflammation was an important cofactor for the occurrence of gingival overgrowth.	18307926
Anxiety, CTCAE 3.0, Depression, CTCAE, Alcoholic Intoxication, Chronic	Altered Intercellular Communication	The dopaminergic neurotransmission system is one of the major factors in development of alcoholism and also contributes to anxiety and depression.	18307984
Tissue damage, Inflammation, Infection	Altered Intercellular Communication	The activation of T cells via ICOS co-stimulation in focal infections likely triggers the skin and skeletal inflammation associated with PPP, resulting in tissue damage.	18308514
Gastrointestinal inflammation	Altered Intercellular Communication	Anti-inflammatory role of sympathetic nerves in chronic intestinal inflammation.	18308830
Sympathectomy	Altered Intercellular Communication	Thus, the loss of sympathetic nerve fibres in the chronic phase of the disease is most probably a pro-inflammatory signal, which might be related to repulsion of these fibres by SEMA3C and other repellents.	18308830
Colitis	Altered Intercellular Communication	Substance P (SP) is a pro-inflammatory neuropeptide in colitis, whereas sympathetic neurotransmitters are anti-inflammatory at high concentrations.	18308830
Inflammation, Structure of appendicular vein	Altered Intercellular Communication	The procedure was uneventful and there was no sign of inflammation around the appendicular orifice or the luminal surface of the cecum.	18309695
Inflammation, Neuralgia, Neuropathy	Altered Intercellular Communication	In this study we evaluated the role of ongoing inflammation and small-fibre neuropathy as possible contributing factors for neuropathic pain.	18309711
Inflammation, Thickened	Altered Intercellular Communication	All nerve biopsies showed inflammation with intraneural inflammation and perineural thickening, and intraneural acid fast bacilli were observed in five biopsies.	18309711
Inflammation, Leprosy	Altered Intercellular Communication	There is evidence of ongoing intraneural inflammation in leprosy patients who have completed MDT.	18309711
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The effects of fluticasone with or without salmeterol on systemic biomarkers of inflammation in chronic obstructive pulmonary disease.	18310480
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Small studies have suggested that inhaled corticosteroids can suppress systemic inflammation in chronic obstructive pulmonary disease (COPD).	18310480
ARCN1 gene, Inflammation	Altered Intercellular Communication	These data suggest that these drugs reduce lung-specific but not generalized biomarkers of systemic inflammation in COPD.	18310480
Inflammation, Atherosclerosis	Altered Intercellular Communication	In addition, SMC proliferation appeared concentric to the vessel lumen, and minimal inflammation was detected, unlike typical atherosclerosis.	18310503
Arthritis	Altered Intercellular Communication	The interaction of NK cells with FLS results in increased IL-15 expression by FLS and the production of proinflammatory chemokines, cytokines, and MMPs, which may contribute to joint inflammation.	18311795
Inflammation	Altered Intercellular Communication	The abundant synovial expression of the RANK/RANKL/Osteoprotegerin system in peripheral spondylarthritis is partially disconnected from inflammation.	18311801
Inflammation, Synovitis	Altered Intercellular Communication	The abundant expression of these factors in SpA peripheral synovitis is largely disconnected from systemic and local inflammation.	18311801
Inflammation, Thrombosis	Altered Intercellular Communication	Inflammation plays a critical role in the pathogenesis of atherothrombosis.	18312408
Inflammation, Swelling	Altered Intercellular Communication	A 27-year-old man presented with swelling and inflammation of his right tibia, which had been present for nearly 3 years.	18312455
Inflammation	Altered Intercellular Communication	Community-base participants for the Physical Activity, Inflammation and Body Composition Trial.	18312558
Inflammation, Obesity	Altered Intercellular Communication	Our results suggest that polymorphisms in the WRN gene might have a significant role regulating PAI-1 levels in healthy individuals and "normal states" as well as acute or chronic stress, obesity, aging, acute inflammation, among others, where characteristic high levels of insulin, TNF alpha and TGFbeta, could favor PAI-1 high levels in carriers with polymorphic variants (C and F alleles), beyond the levels reached by carriers with other alleles (R and L alleles).	18312663
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Impaired exercise tolerance	Altered Intercellular Communication	Inflammation is increased in chronic obstructive pulmonary disease (COPD) and plays a role in exercise intolerance.	18312772
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Whether vitamin B6 exerts an independent or a synergic effect in combination with inflammation for the risk of coronary artery disease (CAD) is unclear.	18312786
Inflammation, Carcinoma of lung	Altered Intercellular Communication	The amount of free DNA is related to the amount of inflammation, but not to the presence of lung cancer.	18313165
Inflammation, Malnutrition	Altered Intercellular Communication	In addition, serum protein concentration is influenced by malnutrition and inflammation.	18313808
Inflammation, Malnutrition	Altered Intercellular Communication	Therefore, evaluation of serum trace elements concentration has to consider influence of malnutrition and inflammation.	18313808
Inflammation, Malnutrition, Tube feeding of patient	Altered Intercellular Communication	We thought that it was effective in nutritional management of patients with malnutrition and inflammation to clarify about correlation among nutritional indices, serum trace elements, and the amount of trace element intake in tube-fed patients.	18313808
Inflammation, Pneumonia	Altered Intercellular Communication	The first group was 20 patients with inflammation (inflammation group), and another group was 20 patients without pneumonia (control group).	18313808
Inflammation, Anemia, Hypoalbuminemia	Altered Intercellular Communication	Subjects were malnourished and showed inflammatory response: low body weight (55%), hypoalbuminemia (58%), moderate or severe inflammation (53%), anemia (38%).	18313808
Tube feeding of patient, Malnutrition, Deglutition Disorders, Inflammation	Altered Intercellular Communication	In tube-fed patients with neurological dysphagia, serum trace elements concentration was influenced by malnutrition and inflammation.	18313808
Inflammation, Malnutrition	Altered Intercellular Communication	It was suggested that serum trace elements concentration might not be normalized if malnutrition and inflammation are not treated.	18313808
Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	Four months after treatment initiation, the penile area was free of inflammation and ulceration.	18314174
Delirium, Inflammation	Altered Intercellular Communication	Delirium has been hypothesized to be a central nervous system response to systemic inflammation during a state of blood-brain barrier compromise.	18314455
Communicable Diseases, Inflammation	Altered Intercellular Communication	We hypothesize that global historical increases in life span at older ages are partly explained by reduced lifetime exposure to infection and subsequent inflammation.	18314457
Communicable Diseases, Inflammation, Chronic disease, Atherosclerosis	Altered Intercellular Communication	Further testing of the links among infection, inflammation, and chronic diseases of aging among the Tsimane requires collection of age-specific indicators of atherosclerosis and cardiac function.	18314457
Gastrointestinal inflammation	Altered Intercellular Communication	It is not clear whether differences in degree of intestinal inflammation or other reasons account for this.	18315580
Communicable Diseases, Inflammation, Atherosclerosis	Altered Intercellular Communication	Several studies have suggested that inflammation and infection may be important for accelerated progression of atherosclerosis, but few data are available on subjects with early stages of atherosclerosis.	18317426
Communicable Diseases, Inflammation, Atherosclerosis	Altered Intercellular Communication	Notably, null findings were obtained by viral and bacteria titers, suggesting a greater role of inflammation (and not of infection) in the progression of atherosclerosis in our cohort.	18317426
Inflammation, Malnutrition, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD) is associated with inflammation and malnutrition and carries a markedly increased risk of cardiovascular disease (CVD).	18317568
Refractory anemias, Arthritis, Synovitis	Altered Intercellular Communication	MIP images were used to review the arthritis of RA patients, and a significant difference was found in the number of synovitis inflammations detected with MIP images when compared with findings after physical examinations.	18317877
Inflammation	Altered Intercellular Communication	Surgical intervention followed by a period of rehabilitation maintained a favourable level of activities of daily living (ADLs), The requirements for favourable life expectancy are control of RA inflammation and maintenance of a favourable level of ADLs.	18317879
Fibrosis Assessment, Glomerulonephritis, Interstitial inflammation	Altered Intercellular Communication	Renal pathology revealed crescentic glomerulonephritis with interstitial inflammation and fibrosis.	18318246
Inflammation	Altered Intercellular Communication	Both genes encode proteins playing a role in the synthesis of the pro-inflammatory leukotriene B mediators, possibly providing a link between MI and inflammation.	18318662
Inflammation, Keratosis	Altered Intercellular Communication	Patients undergoing capecitabine therapy may experience inflammation and irritation of existing actinic keratoses.	18319010
Communicable Diseases, Chlamydia, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation and infectious agents such as Chlamydia pneumoniae have been associated with cardiovascular disease.	18319525
Inflammation, Hemorrhage, Swelling	Altered Intercellular Communication	Double-balloon enteroscopy (DBE) showed diffuse swelling of the small intestine, petechial bleeding in the jejunum, and focal inflammation of the ileum.	18320317
Inflammation	Altered Intercellular Communication	Histological examination showed aspecific signs of inflammation due to a foreign body, and haemorrhagic material without epithelial lining.	18320949
Intraocular inflammation, Endophthalmitis, CTCAE	Altered Intercellular Communication	Endophthalmitis and serious intraocular inflammation occurred, respectively, in 2.9% and 12.4% of ranibizumab + PDT patients and 0% of PDT-alone patients.	18321465
Inflammation, Hypertension, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	After controlling for potentially confounding variables including demographics, duration of disease, active intraocular inflammation, history of diabetes mellitus or hypertension, and presence of epiretinal membrane, actively smoking at presentation was associated with a four-fold increased risk of CME at presentation vs never smoking (odds ratio (OR), 3.90; 95% confidence interval (CI), 1.43, 10.66; P = .008).	18321467
Inflammation, Fibrosis Assessment, Fatty degeneration, Steatohepatitis	Altered Intercellular Communication	We examined the relationship between severity and zonal location of steatosis and the following: lobular inflammation, presence of ballooning, Mallory bodies, fibrosis score, and definite steatohepatitis.	18321606
Inflammation, Fibrosis Assessment, Fatty degeneration, Steatohepatitis	Altered Intercellular Communication	Increasing levels of steatosis severity were positively associated with lobular inflammation (p<0.0001), zone 3 fibrosis (p<0.001), and definite steatohepatitis (p=0.02), but were unrelated to ballooning, Mallory bodies, or advanced fibrosis.	18321606
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The grades of inflammation and fibrosis were obtained through hepatic biopsy performed on all the patients.	18322608
Inflammation	Altered Intercellular Communication	A bone marrow biopsy specimen showed granulomatous inflammation and BCG was cultured from the urine.	18322775
Inflammation	Altered Intercellular Communication	Histology of liver biopsy specimens showed portal inflammation in 73.3%, centrilobular necrosis in 80%, lobular inflammation in 66.7%, hepatocellular apoptosis in 66.6% and cholangitis/cholangiolitis in 20% of patients.	18322953
Cessation of life, Inflammation	Altered Intercellular Communication	Among the histological features, the presence of portal inflammation in liver biopsy was associated with increased hospitalization in the ICU prior death (P=0.026).	18322953
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Signaling events after activation of toll-like receptors (TLRs) are important mechanisms promoting inflammation in the atherosclerotic plaque.	18323517
Inflammation, Corneal Stroma, Edema	Altered Intercellular Communication	The edema of corneal stroma and inflammation of anterior chamber was shown at immediate-postoperative period, but completely subsided 2 weeks later.	18323708
Inflammation, Traumatic injury	Altered Intercellular Communication	Altered gene expression patterns in dendritic cells after severe trauma: implications for systemic inflammation and organ injury.	18323745
Inflammation, Traumatic injury	Altered Intercellular Communication	Furthermore, these data confirm and expand the central role of chemokines and lipid mediators as effector molecules of DC-mediated immune responses in systemic inflammation associated with severe trauma.	18323745
methyldopa, Inflammation, Age related macular degeneration	Altered Intercellular Communication	Inflammation has long been suspected to play a role in the pathogenesis of age-related macular degeneration (AMD).	18325906
Tumor necrosis, Inflammation, Neoplasms	Altered Intercellular Communication	Tumour necrosis factor-alpha (TNF-alpha) is an important regulator of the chronic inflammation contributing to tumour progression.	18325912
Inflammation, Tuberculosis	Altered Intercellular Communication	The comprehensive examination made the diagnosis of tuberculosis be cancelled in 35% of cases and confirmed in 65%, by determining the phase and extent of a specific inflammation.	18326208
Communicable Diseases, Inflammation	Altered Intercellular Communication	High tuberculous infection activity and mediastinal ILN lesion in different phases of the specific inflammation were found in 15.4%, which was indicative of the chronic course of inflammation.	18326208
Microalbuminuria, Inflammation, Diabetic Nephropathy	Altered Intercellular Communication	Urinary excretion of proinflammatory cytokines and TGF-b was elevated in patients with DM-1 having micro- and macroalbuminuria suggesting participation of inflammation in development of diabetic nephropathy.	18326229
Inflammation, Demographics Domain, Atherosclerosis, Diabetes Mellitus, Obesity	Altered Intercellular Communication	Considering the role played by inflammation in the development of atherosclerosis, and inflammatory activity in obesity and diabetes mellitus (DM), a range of common and interrelated elements of these processes may be marked out.	18326279
Inflammation, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	Association of inflammation with anaemia in patients with chronic kidney disease not requiring chronic dialysis.	18326562
Enterocolitis, Neutropenic, Typhlitis, Inflammation, Colitis	Altered Intercellular Communication	Neutropenic enterocolitis or typhlitis (from the Greek typhlon, meaning caecum) is defined as a necrotizing colitis with inflammation of the cecum and surrounding tissues.	18326897
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	The results indicate the presence of chronic and persistent pulmonary inflammation in stable patients with COPD.	18327434
Airway structure, Lung diseases	Altered Intercellular Communication	Induced sputum is a useful technique for assessing airway inflammation, but its role in the diagnosis of lung disease in immunosuppressed patients needs further investigation.	18327465
Tissue damage, Inflammation	Altered Intercellular Communication	In addition, those cells might be associated with the inflammation and tissue damage of the salivary glands.	18328140
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus	Altered Intercellular Communication	Future studies examining the causal relationship between plasma resistin concentrations, chemokine markers of inflammation, CVD, and diabetes are warranted.	18328350
Inflammation	Altered Intercellular Communication	Evidence emerged that suggested inflammation was associated with risk of AF.	18328851
vascular inflammations	Altered Intercellular Communication	Helicobacter pylori causes gastric and esophageal inflammation, as well as systemic and vascular inflammation.	18328851
Inflammation, Diverticulum	Altered Intercellular Communication	This view is supported by the absence of inflammation and infiltration of neutrophils on histopathological examination of the diverticula.	18330630
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation of the airways.	18330638
Inflammation	Altered Intercellular Communication	In the majority of cases, the inflammation is triggered by tobacco smoke.	18330638
Pain Distress Question, Inflammation, Hyperlipidemia, Diabetes Mellitus, Anterior Ischemic Optic Neuropathy, Hypertension, CTCAE	Altered Intercellular Communication	Since he did not complain of eye pain, his blood examination showed no reaction of inflammation, and he had hypertension, diabetes mellitus and hyperlipidemia, anterior ischemic optic neuropathy was diagnosed.	18332580
Inflammation, Vascular lesions	Altered Intercellular Communication	Inflammation and vascular lesions were unremarkable in the biopsy specimens.	18332636
Tumor necrosis, Inflammation, Heart failure	Altered Intercellular Communication	Tumor necrosis factor (TNF-alpha) and plasma levels of soluble tumor necrosis factor receptor I (sTNFR-I) are increased in patients with heart failure as an expression of chronic inflammation, representing a negative prognostic factor.	18333356
Inflammation, Heart failure, Anemia	Altered Intercellular Communication	In patients with heart failure, increased sTNFR-I as an expression of chronic inflammation is correlated with both anemia and low serum lipid fractions even if the exact nature of the relationship has yet to be established.	18333356
Inflammation, Raynaud Phenomenon, Scleroderma , Endothelial dysfunction	Altered Intercellular Communication	20 scleroderma patients with severe Raynaud phenomenon, under aspirin treatment, were evaluated by quantitative flow-cytometry for PAM (P-selectin, GPIIbIIIa, CD40L) in correlation with scleroderma activity and severity, systemic endothelial dysfunction (flow-mediated vasodilatation), systemic inflammation (serum CRP and IL-6) and cold-provocation test.	18333373
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	NSAIDs decreased the odds of developing post-CTS atrial fibrillation, further supporting the hypothesis of inflammation as a trigger for post-CTS atrial fibrillation.	18334081
Inflammatory Bowel Diseases, Inflammation, Thrombosis	Altered Intercellular Communication	Inflammation and thrombosis are closely related processes, which may play a role in the pathogenesis, as well as complications, of inflammatory bowel disease (IBD).	18334871
Inflammation, Sigmoid Diseases	Altered Intercellular Communication	The aim of this study was to check the results of laparoscopic sigmoid resection for sigmoid diverticular disease with respect to stage of inflammation and time of surgical intervention.	18335181
Inflammation, Intrahepatic Cholangiocarcinoma	Altered Intercellular Communication	Impact of systemic inflammation on outcome following resection for intrahepatic cholangiocarcinoma.	18335453
Inflammation, Facial paralysis	Altered Intercellular Communication	[Etiological factor analysis of facial nerve paralysis due to chronic inflammation of middle ear].	18335744
Inflammation, Facial paralysis	Altered Intercellular Communication	To discuss the etiological factors of facial nerve paralysis due to chronic inflammation of middle ear.	18335744
Inflammation, Facial paralysis	Altered Intercellular Communication	This retrospective research included 41 patients operated for facial nerve paralysis due to chronic inflammation of middle ear.	18335744
Inflammation, Cholesteatoma, Facial paralysis	Altered Intercellular Communication	Facial nerve paralysis due to chronic inflammation of middle ear was frequently relevant with cholesteatoma,the tympanic segment of the fallopian canal was most location to be involved in.	18335744
Inflammation, Fatty degeneration	Altered Intercellular Communication	Steatosis alone was present in more than a quarter of the cases and steatosis along with inflammation was present in half.	18335793
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	The magnitude of steatosis correlated with inflammation, while both these seemed to correlate with hepatocyte Injury and fibrosis.	18335793
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	An Increasing grade of steatosis is associated with greater Inflammation, hepatocyte injury and acinar fibrosis.	18335793
Inflammation, Non-alcoholic Fatty Liver Disease, Fatty degeneration	Altered Intercellular Communication	Preferential involvement of acinar zone 2 by steatosis, the morphology of the steatotic cells, and nature and location of inflammation are important in the diagnosis of NAFLD and its differentiation from other causes of fatty liver.	18335793
Inflammation, Fever, CTCAE, Neoplasms, Refractory anemias, Chronic infectious disease, Juvenile Chronic Polyarthritis, Renal Cell Carcinoma Pathway, Rheumatoid Arthritis, Chronic disease, Hodgkin Disease, Familial Mediterranean Fever, Spondylitis	Altered Intercellular Communication	The later (AA), is caused by deposition of fibrils composed of fragments of the acute phase reactant serum amyloid A (SAA) and complicates chronic diseases with ongoing or recurring inflammation, namely; rheumatoid arthritis (RA), juvenile chronic polyarthritis, ankylosing spondylitis, familial periodic fever syndromes (Familial Mediterranean Fever), chronic infections and furthermore, some neoplasms (mainly renal cell carcinoma and Hodgkin's disease).	18336138
Inflammation, Ankylosis	Altered Intercellular Communication	In real-life clinical practice, patients with established disease with spinal ankylosis and high levels of inflammation and disease activity can achieve a major clinical response with infliximab.	18336538
Inflammation	Altered Intercellular Communication	Regulation of galectin-3 function in mucosal fibroblasts: potential role in mucosal inflammation.	18336593
Inflammation	Altered Intercellular Communication	Little information exists regarding the prognostic role of biomarkers of inflammation in Mediterranean patients.	18336825
Inflammation, Deficiency of butyryl-CoA dehydrogenase, Diverticulosis, Colitis	Altered Intercellular Communication	Localized inflammation of the sigmoid colon or segmental colitis associated with diverticulosis (SCAD syndrome) is an increasingly recognized, apparently uncommon, clinical and pathological disorder usually described in older adults.	18338265
Inflammation	Altered Intercellular Communication	Increased production of VEGF in the injured lung may contribute to resolution of inflammation in the lung.	18339029
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Inflammation plays a pathogenic role in the development of chronic heart failure (CHF).	18339317
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	CXC ligand 16 (CXCL16) may be involved in inflammation and lipid metabolism, and we hypothesized a role for this chemokine in coronary artery disease (CAD).	18339644
Inflammation	Altered Intercellular Communication	Our findings suggest that soluble CXCL16 could be linked to atherogenesis not only as a marker of inflammation, but also as a potential inflammatory mediator.	18339644
Inflammation, Chylous effusion	Altered Intercellular Communication	We hypothesized that chylous effusions from a thoracic duct leak alone have low lactate dehydrogenase (LDH) concentrations due to the absence of inflammation and are lymphocyte-predominant, protein-discordant exudates.	18339791
AURKAIP1 gene, Autoimmune Pancreatitis, Waldenstrom Macroglobulinemia	Altered Intercellular Communication	Autoimmune pancreatitis (AIP) is characterized by high serum IgG4 concentrations, lymphoplasmacytic inflammation, and a favorable response to corticosteroid treatment.	18341485
Granulomatous inflammation	Altered Intercellular Communication	Histologic examination of the mass revealed granulomatous inflammation, an extremely rare manifestation of this disease.	18342212
Inflammation, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	Evaluation of prostatitis in autopsied prostates--is chronic inflammation more associated with benign prostatic hyperplasia or cancer?	18343414
Inflammation, Prostate carcinoma, Benign prostatic hypertrophy	Altered Intercellular Communication	Chronic inflammation is associated with prostate cancer and benign prostatic hyperplasia.	18343414
Inflammation	Altered Intercellular Communication	However, the prevalence of chronic inflammation in malignant and benign glands has not been compared.	18343414
Inflammation, Primary malignant neoplasm, Benign prostatic hypertrophy	Altered Intercellular Communication	We evaluated the association of inflammation, benign prostatic hyperplasia and cancer in autopsied prostates.	18343414
Inflammation, Primary malignant neoplasm, Benign prostatic hypertrophy	Altered Intercellular Communication	Pathological analysis identified each focus of cancer, benign prostatic hyperplasia nodules and areas of acute or chronic inflammation.	18343414
Inflammation, Primary malignant neoplasm, Benign prostatic hypertrophy	Altered Intercellular Communication	Any cancer focus or benign prostatic hyperplasia nodule involved directly with inflammation was recorded.	18343414
Inflammation, Prostate carcinoma, Benign prostatic hypertrophy	Altered Intercellular Communication	The association of the prevalence of prostate cancer, benign prostatic hyperplasia and inflammation was statistically assessed.	18343414
Inflammation	Altered Intercellular Communication	Chronic inflammation was identified in 88 (53%), acute inflammation in 6 (4%), and chronic inflammation and acute inflammation in 19 (11%) glands.	18343414
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Of the glands harboring benign prostatic hyperplasia 75% were also involved with chronic inflammation compared to only 50% of those without benign prostatic hyperplasia (p <0.01).	18343414
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Comparatively the glands with or without any evidence of cancer were similarly involved with chronic inflammation (55% vs 58%, p >0.1).	18343414
Inflammation, Primary malignant neoplasm, Benign prostatic hypertrophy	Altered Intercellular Communication	Of the 27 glands involved with cancer and benign prostatic hyperplasia, chronic inflammation was more associated with benign prostatic hyperplasia than cancer (p = 0.006).	18343414
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Acute inflammation was not significantly associated with either benign prostatic hyperplasia or cancer.	18343414
Heart failure, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Recent studies on the pathophysiology of heart failure indicate the role of neurohormones and immune and inflammatory processes as potential mechanisms involved in the pathogenesis and clinical course of chronic heart failure (CHF).	18344152
Inflammation	Altered Intercellular Communication	Histological assessment of the explanted bovine ureters revealed acute and chronic transmural inflammation.	18344206
Coronary Arteriosclerosis, Renal sclerosis with hypertension	Altered Intercellular Communication	Myeloperoxidase (MPO) may play an important role not only in host defense reactions but also in local inflammations, especially in atherosclerotic diseases such as hypertensive nephrosclerosis (HN).	18344624
Inflammation, Protein-Energy Malnutrition	Altered Intercellular Communication	Prealbumin, due to its short half-life, is a suitable indicator of changes in protein-energy balance, but its levels show, as with other serum proteins, a decrease in the case of inflammation too.	18345263
Inflammatory abnormality of the eye	Altered Intercellular Communication	There was no difference between the patients with TBU and those with non-TBU in terms of the status of ocular inflammation or the tuberculin skin testing results.	18345453
Pharyngitis	Altered Intercellular Communication	Regular ICS users had significantly more pharyngeal inflammation and throat discomfort (P<0.0001).	18346871
Pharyngitis, Inflammation	Altered Intercellular Communication	A higher pharyngitis score did not correlate with any of the histological markers of inflammation (P>0.01).	18346871
Oropharyngeal, Inflammation	Altered Intercellular Communication	However, histological markers and oropharyngeal redness are not reliable measures of inflammation.	18346871
Diarrhea, Anorexia, Nausea, Inflammatory disease of mucous membrane, Fatigue	Altered Intercellular Communication	The most common AEs were fatigue, nausea, diarrhea, mucosal inflammation, and anorexia.	18347007
Inflammation	Altered Intercellular Communication	Biopsy of a sino-orbital lesion suggested nonspecific inflammation.	18347456
Diverticular disease of colon, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Assessment and grading of mucosal inflammation in colonic diverticular disease.	18347509
Inflammation	Altered Intercellular Communication	In particular, it is unknown whether inflammation may be found in every degree of DD.	18347509
Inflammation	Altered Intercellular Communication	A pediatric perspective on inflammation and oxidative stress in response to exercise.	18347698
Radiculitis, Rhabdomyositis	Altered Intercellular Communication	There was mild inflammation of peripheral nerve roots but no spheroid, and patchy chronic inflammation of skeletal muscle.	18347805
Inflammation, Impaired cognition	Altered Intercellular Communication	Obesity-associated inflammation is much more prominent in females and it appears to be associated with cognitive dysfunction, particularly of frontal lobe tasks.	18347963
Communicable Diseases, Inflammation	Altered Intercellular Communication	Our study epidemiologically confirmed that atrophic changes caused by Hp infection determine the development of differentiated-type ncGC, and the inflammation itself induced by Hp infection promotes the development of undifferentiated-type ncGC.	18347999
Crohn Disease, Inflammation	Altered Intercellular Communication	In Crohn's disease (CD), inflammation is driven by luminal commensal micro-organisms; however, mechanisms of early phases of inflammation need further clarification.	18348161
Inflammation, Chagas Disease	Altered Intercellular Communication	It therefore appears that the host's anti-oxidant defence responses (at least in terms of elevated concentrations of SOD) may inhibit inflammation during the indeterminate phase of Chagas disease.	18348773
Inflammation, Infection of bone	Altered Intercellular Communication	99mTc-depreotide in the evaluation of bone infection and inflammation.	18349794
Inflammation, Infection of bone	Altered Intercellular Communication	Based on this property this study tried to investigate whether (99m)Tc-depreotide scintigraphy could be a useful complementary method in the investigation of bone infection and inflammation.	18349794
Osteomyelitis, Fracture, Degenerative polyarthritis, Bone necrosis	Altered Intercellular Communication	Negative (99m)Tc-depreotide scans were acquired in five cases of 'no-inflammation' (an uncomplicated fracture, an aseptic loosening of prosthesis, an old osteonecrosis, a healed and a successfully treated osteomyelitis), as well as in 14/14 total sites of degenerative arthritis-osteoarthropathy.	18349794
Inflammation, Infection of bone	Altered Intercellular Communication	(99m)Tc-depreotide can be a useful complementary imaging method in the evaluation of bone infection and inflammation.	18349794
Inflammation, Fever of Unknown Origin	Altered Intercellular Communication	Equally, the higher NPV in patients with spontaneous FUO virtually excludes infection/inflammation.	18349799
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	The material of appendectomy was examined, acute appendicitis was verified and graded according to the severity of inflammation and eosinophilic infiltration rate in the wall of appendix by a pathologist.	18350341
eosinophil, Inflammation	Altered Intercellular Communication	There was no significant difference between eosinophilic infiltration rate, peripheral eosinophil count, severity of inflammation, and Alvarado score of mix prick test positive and negative patients in study group.	18350341
eosinophil, Inflammation	Altered Intercellular Communication	However, eosinophilic infiltration rate, inflammation grade, and peripheral eosinophil count were not able to explain the relationship between the two conditions.	18350341
Airway structure, Allergy - Charge Type Reason	Altered Intercellular Communication	Laboratory animal allergy (LAA) may cause eosinophilic airway inflammation, for which exhaled nitric oxide (FE(NO)) measurements are sensitive and specific.	18350400
Airway structure	Altered Intercellular Communication	Baseline FE(NO) was high (> 150 ppb) in the two seropositive subjects and increased progressively during the working week in one subject, confirming exposure-driven airway inflammation.	18350400
Asthma	Altered Intercellular Communication	Exhaled nitric oxide and induced sputum eosinophils are well established as direct markers of inflammation/oxidative stress in asthma.	18350407
Airway structure	Altered Intercellular Communication	Sputum 8-isoprostane was not elevated in asthmatics compared to healthy subjects (children 81.1 vs. 89.9 and adults 76.9 vs. 73.4 pg/mL) and did not correlate with lung function or other measurements of airway inflammation.	18350407
Alveolar, Inflammation	Altered Intercellular Communication	A lung biopsy revealed chronic inflammation without evidence of alveolar capillaritis.	18350456
Liver neoplasms	Altered Intercellular Communication	The inflammation-associated transcripts pointed to limited alterations of free iron metabolism in alcoholic vs hepatitis C tumors.	18350606
Inflammation	Altered Intercellular Communication	Obturation of bronchial tree as well as pulmonary parenchyma lesion caused by chronic inflammation process results in considerable limitation of patients' functional capacity and worsening of their physical activity.	18350714
Refractory anemias, Inflammation	Altered Intercellular Communication	Cytokines and immune cells networks have been identified as important mediators in the pathogenesis and perpetuation of inflammation in RA.	18351144
Inflammation, Sample Size Calculation, Lung Diseases, Interstitial	Altered Intercellular Communication	These findings suggest that EBC sampling permits the non-invasive study of inflammation in SSc patients, and may be correlated with the severity of interstitial lung disease.	18351434
Eye pain, Inflammatory abnormality of the eye, Epithelial	Altered Intercellular Communication	Primary outcome measures were ocular pain and epithelial defects; secondary measures were visual acuity and ocular surface inflammation.	18352868
Pain Distress Question, Conjunctivitis	Altered Intercellular Communication	It has been shown to alleviate pain, promote corneal epithelialization and reduce conjunctival inflammation whereas in some cases it may also improve visual acuity.	18352868
Inflammation, Cystitis, Ulcer	Altered Intercellular Communication	Patients with ulcer consistently had bladder inflammation but the cystoscopic finding of ulcers was not a sensitive indicator of inflammation on bladder biopsy.	18353383
Inflammation, Pelvic Pain	Altered Intercellular Communication	The chronic pelvic pain syndrome is characterized by pelvic pain, voiding symptoms and varying degrees of inflammation within expressed prostatic secretions.	18353390
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	From our results, we can conclude that the addition of preoperative chemotherapy to radiotherapy led to significantly less COX-2 upregulation, less proliferation and more inflammation, as was seen in the resection specimen as well as less invasion and metastasis.	18353631
Inflammation, Chronic heart failure	Altered Intercellular Communication	Clinical and experimental studies suggest a pathogenic role for inflammation in chronic heart failure (HF).	18353719
Inflammation	Altered Intercellular Communication	Brain magnetic resonance imaging (MRI) revealed multiple lesions (hyperintense on T2 and slightly hypointense on Tl) involving mainly white matter suggestive of inflammation.	18355336
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	TGF-beta is thought to participate in chronic inflammation and fibrosis.	18355371
Inflammation	Altered Intercellular Communication	These results establish the heterogeneous responsiveness of fibroblast populations in the airways to TGF-beta(1) and that such a heterogeneity may contribute, at least in part, to the different pathological outcomes of inflammation in the upper and lower airways.	18355371
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Oxidative modification of circulating lipids contributes to inflammation and endothelial dysfunction, which are hallmark features of atherosclerosis.	18355658
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	Suppressor of cytokine signaling 1 inhibits pulmonary inflammation and fibrosis.	18355908
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	We sought to investigate the role of SOCS1 in pulmonary inflammation and fibrosis in vivo.	18355908
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	SOCS1-haplodeficient mice treated with bleomycin (BLM) were evaluated for pulmonary inflammation and fibrosis compared with wild-type mice.	18355908
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	SOCS1-haplodeficient mice treated with BLM showed markedly enhanced pulmonary inflammation and fibrosis compared with wild-type mice.	18355908
Inflammation, Lung Injury, Pulmonary Fibrosis	Altered Intercellular Communication	Adenoviral SOCS1 gene transfer to murine lungs significantly decreased lymphocytic inflammation, pulmonary fibrosis, and mortality because of BLM-induced lung injury.	18355908
Inflammation, Fibrous	Altered Intercellular Communication	Utility of USPIO-enhanced MR imaging to identify inflammation and the fibrous cap: a comparison of symptomatic and asymptomatic individuals.	18356000
Inflammation, Atheroma	Altered Intercellular Communication	Inflammation is a risk factor the vulnerable atheromatous plaque.	18356000
Trachoma , Chlamydia trachomatis, Inflammation	Altered Intercellular Communication	Community summarized mean prevalence, overall, was 35.6% (SD = 17.6) for active trachoma, 34.0% (18.7) for trachomatous inflammation, follicular (TF) alone and 4.3% (5.3) for PCR positivity for C. trachomatis.	18356196
Cerebrovascular Disorders, Inflammation, Dental Plaque	Altered Intercellular Communication	However, the correlation between the plaque expression of Lp-PLA(2) and plaque oxidative stress, inflammation, and stability as well as the clinical presentation remains poorly defined, especially for cerebrovascular disease.	18356547
Inflammation	Altered Intercellular Communication	Symptomatic carotid artery plaques are characterized by increased levels of Lp-PLA(2) and its product lysoPC in correlation with markers of tissue oxidative stress, inflammation, and instability.	18356547
Inflammation, Malignant Neoplasms, Chronic osteomyelitis	Altered Intercellular Communication	The prostate biopsy showed acute inflammation with no malignancy and the lumbar spine biopsy showed chronic osteomyelitis.	18356681
Conjunctivitis	Altered Intercellular Communication	Postoperatively the patient developed intense conjunctival inflammation and diffuse symblepharon formation.	18356734
Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	These results support the role of endothelial dysfunction and subclinical inflammation as important mechanisms in the etiopathogenesis of type 2 diabetes; moreover, they indicate that novel biomarkers may improve the prediction of type 2 diabetes beyond the use of traditional risk factors alone.	18356828
Inflammation, Critical Illness	Altered Intercellular Communication	In unselected critically ill medical patients, fish oil supplementation that increased the n-3/n-6 PUFA ratio to 1:2 did not affect inflammation or clinical outcome, compared to parenteral lipid nutrition with an MCT/LCT emulsion.	18357434
Dual-probe in Situ Hybridization, Inflammation, Hyperostosis, Diffuse Idiopathic Skeletal, Macular degeneration	Altered Intercellular Communication	The last represents either pronounced tendinous inflammation, albeit in the context of no articular degenerations, or a case of diffuse idiopathic skeletal hyperostosis (DISH) in the Late Pleistocene.	18357583
Inflammation	Altered Intercellular Communication	After surgical drainage, the inflammation mucosa of lacrimal sac might return to normal and the function of nasolacrimal apparatus might recover.	18357705
Airway structure, Asthma	Altered Intercellular Communication	Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model.	18359884
Pneumonitis	Altered Intercellular Communication	In this study, we hypothesized that SPHK inhibition could ameliorate lung inflammation in ovalbumin (OVA)-challenged mouse lungs.	18359884
Asthma, Eosinophilic inflammation	Altered Intercellular Communication	These data suggest that the inhibition of SPHK affected acute eosinophilic inflammation induced in antigen-challenged mouse model and that targeting SPHK may provide a novel therapeutic tool to treat bronchial asthma.	18359884
Acute myocardial infarction, Inflammation	Altered Intercellular Communication	The etiology of 'smoker's paradox' in acute myocardial infarction with special emphasis on the association with inflammation.	18360061
Inflammation, Neoplasms	Altered Intercellular Communication	Host inflammation was determined (CRP, ESR) in relationship to tumor differentiation and stage.	18360718
Inflammation, Neoplasms	Altered Intercellular Communication	Systemic inflammation was predicted by p15, TGFbeta3 and Bcl-2 in tumor tissue (p<0.001).	18360718
Malignant tumor of colon, Inflammation	Altered Intercellular Communication	Our results connect systemic inflammation and survival to COX-2 staining and increased PGE2 in colon cancer.	18360718
Inflammation, Vascular System Injuries	Altered Intercellular Communication	Inflammation is the primary response to vessel wall injury caused by stent placement in coronary arteries.	18361937
Inflammation	Altered Intercellular Communication	More recently, an abundance of resistin was detected in macrophages, which suggests its important role in inflammation.	18362311
Prostate carcinoma, prostatitis	Altered Intercellular Communication	Subclinical prostatic inflammation potentially contributes to an elevated PSA level and its variation among prostate cancer suspects.	18362491
Inflammatory abnormality of the eye, Epithelial	Altered Intercellular Communication	To describe the formation of deep calcareous degeneration of the cornea associated with the use of preservative-free eyedrops in patients with a persistent epithelial defect and active ocular surface inflammation.	18362655
Inflammation, Dystrophic calcification, Epithelial	Altered Intercellular Communication	All 6 cases of calcareous degeneration of the cornea had persistent epithelial defects, treated with preservative-free medications (timolol, dexamethasone, and prednisolone), in the presence of active inflammation on the ocular surface.	18362655
Lesion of cervix, Precocious	Altered Intercellular Communication	The LIFS using excitation wavelength of 488 nm could be used to differentiate HGSIL lesions from LGSIL and CC inflammation, and could help a precocious and less invasive diagnosis of cervix lesions.	18363079
Inflammation, Ascites, Communicable Diseases, Edema, Toothache	Altered Intercellular Communication	In Taiwan, Solanum indicum L. has been used in folk medicine for the treatment of inflammation, toothache, ascites, edema, and wound infection.	18363121
Inflammation	Altered Intercellular Communication	P-selectin is an adhesion molecule known to be involved in the pathogenesis of several diseases through its major role in the initial phase of leukocytes recruitment during inflammation.	18363816
Inflammation	Altered Intercellular Communication	TNFalpha has a crucial role in chronic inflammation.	18363845
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	TNFalpha blockade is effective in preventing inflammation in early phase of IBD, maintaining the homeostatic balance of apoptosis.	18363845
Inflammation, Pain Distress Question, Psoriasis, Hyperkeratosis, Communicable Diseases	Altered Intercellular Communication	The use of BoNTA in inverse psoriasis would be a novel approach compared with conventional treatments and may act at the neuroglandular junction level to reduce local sweating with its consequent skin maceration and secondary infection and at the extra-junction level to inhibit the liberation of neuropeptides and other pro-algogenic substances responsible for inflammation, hyperkeratosis and pain transmission.	18363911
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Cytokine-induced inflammation is the predominant underlying mechanism in chronic obstructive pulmonary disease (COPD).	18364273
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Clinical evaluation and power Doppler sonography in rheumatoid arthritis: evidence for ongoing synovial inflammation in clinical remission.	18364651
Inflammation	Altered Intercellular Communication	A majority of patients who were in clinical remission according to American College of Rheumatology or DAS28 criteria had ongoing synovial inflammation on power Doppler ultrasound (58% and 62%, respectively).	18364651
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	Power Doppler examination of rheumatoid hand joints is a practical method to estimate synovial inflammation.	18364651
Inflammation, Inflammatory disorder of cartilage	Altered Intercellular Communication	When a chondritis had been confirmed by PET, therapy was started, and the course of inflammation was monitored.	18365226
Inflammatory abnormality of the eye, Behcet Syndrome, Vasculitis, CTCAE, Ulcer	Altered Intercellular Communication	Behcet's disease is a systemic vasculitis affecting arterioles and venules and is characterized by recurrent oral ulcers, genital ulcers and ocular inflammation.	18365598
Superficial ulcer, Hemorrhage, Inflammation, Stenosis	Altered Intercellular Communication	VCE detected jejunal polyps in 6 patients (46.2%), ulcerated stricture in 3 (23%), and erosions, stricture with ileal inflammation, submucosal nodule and active bleeding in 4 patients, respectively.	18365916
Cessation of life, Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	Sarcoidosis is a multisystem disease of uncertain etiology characterized by multifocal areas of discrete and confluent granulomatous inflammation that may rarely be responsible for sudden and unexpected death.	18366580
Inflammation, Neoplasms	Altered Intercellular Communication	Recent studies suggest an association between chronic inflammation, modulating the tissue microenvironment, and tumor biology.	18366696
Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) is increasingly viewed as an inflammatory condition of the sinonasal mucosa interacting with bacteria and/or fungi.	18366797
Interstitial inflammation	Altered Intercellular Communication	A significant number of plasmacytoid dendritic cells (identified as BDCA-2 positive cells) were seen at sites of interstitial inflammation, including follicular aggregates of inflammatory cells.	18368027
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	We examined the mechanism of serotonin-induced inflammation and its antagonists in OA.	18368410
Inflammation	Altered Intercellular Communication	The majority of the indexes (LII, LymI, LSI, LI, LESRRI, LGI, and LMRI) in acute inflammation processes and some of them (LESRRI, NLymRI, and LMRI) in chronic inflammation altered significantly in all the age groups, which demonstrated that compensatory and adaptive mechanisms remained preserved in the elderly.	18368793
Inflammation	Altered Intercellular Communication	In acute inflammation, there were no significant differences from the controls in NlymRI in Group 3, while this parameter in Groups 1 and 2 differ from that in the controls.	18368793
Infarction, Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Subgroup analyses identified National Institutes of Health Stroke Scale score, age, markers of inflammation, blood glucose, and right-sided infarct as predictors of poor outcome.	18369171
Cessation of life, Inflammation	Altered Intercellular Communication	Despite clinical recovery, many patients with CAP leave hospital with ongoing subclinical inflammation, which is associated with an increased risk of death.	18369199
Inflammation, Primary malignant neoplasm, Degenerative disorder, Chronic disease	Altered Intercellular Communication	However, if stress persists, it may lead to chronic diseases, ranging from inflammation and cancer to degenerative diseases.	18370605
Inflammation	Altered Intercellular Communication	Inflammation is a critical defense mechanism, that, uncontrolled, contributes to chronic conditions with inflammatory pathogenesis.	18370605
Inflammation, Metabolic Syndrome X, Pathology, Cardiovascular Diseases	Altered Intercellular Communication	Subclinical chronic inflammation is an important pathogenic factor in the development of metabolic syndrome, a cluster of common pathologies, including cardiovascular disease.	18370605
Vitreous inflammatory cells	Altered Intercellular Communication	Despite 3 weeks of prophylactic antibiotherapy, his visual acuity remained only for the perception of light and vitreous inflammation increased.	18370878
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Estimated glomerular filtration rate, inflammation, and cardiovascular events after an acute coronary syndrome.	18371483
Inflammation	Altered Intercellular Communication	High levels of IL-1beta, IL-6, TNFa were detected in young patients with narcotic drug consumption history, with high enxymatic activity, biliary inflammation, genotype 1b, high index of histological activity.	18372599
Inflammation, Gland	Altered Intercellular Communication	Histological severity of inflammation and glandular atrophy in the antrum were assessed according to the updated Sydney System.	18373163
Symptoms, Inflammation, Gland	Altered Intercellular Communication	Histological severity of inflammation and glandular atrophy were not associated with dyspeptic symptoms.	18373163
Sclerosis, Inflammation	Altered Intercellular Communication	[Sclerotic inflammation of the orbit and multifocal fibrosclerosis syndrome].	18373300
Orbital Pseudotumor	Altered Intercellular Communication	Idiopathic Sclerotic Inflammation of the orbit is a rare pathological entity, with similar clinical and radiological characteristics to orbital pseudo-tumour.	18373300
IL13 gene	Altered Intercellular Communication	S100A7 protein levels are decreased in nasal lavage fluid from individuals with ongoing allergic rhinitis, suggesting a role for S100A7 in allergic airway inflammation.	18373864
allergic inflammation, IL13 gene	Altered Intercellular Communication	The results indicate that rs3014837 is linked to allergic rhinitis in our Swedish population and render S100A7 a strong candidate for further investigations regarding its role in allergic inflammation.	18373864
Inflammation, Chronic heart failure, Endothelial dysfunction	Altered Intercellular Communication	Increased oxidative stress, a common feature in chronic heart failure, has been associated with inflammation, endothelial dysfunction, and extracellular matrix degradation.	18374881
Inflammation	Altered Intercellular Communication	Proximal nail fold inflammation can be caused by many diseases and has not previously been recognized as a result of posterior embedding of the nail.	18375016
Inflammation, Traumatic injury	Altered Intercellular Communication	Persistent proximal nail fold inflammation can result from an episode of trauma that disturbs longitudinal nail growth and results in reverse embedding of the nail plate.	18375016
Pain Distress Question, Inflammation	Altered Intercellular Communication	This can cause pain, inflammation, and granulation tissue formation, and is typically relieved by avulsion and antiinflammatory treatment.	18375016
Inflammation, Weight decreased, Cachexia	Altered Intercellular Communication	Key defining features of cachexia in humans (weight loss, reduced food intake and systemic inflammation) now provide not only a framework for classification but also a rationale for targets for therapeutic intervention.	18375115
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation has been indicated to play a major role in the development of atherosclerosis.	18376126
Inflammation, Pancreatitis, Endotoxemia, septic	Altered Intercellular Communication	A clinical study was made to test the hypothesis that gut mucosal damage happens and correlates with endotoxemia, systemic inflammation, severity of disease, septic complication, and outcome in acute pancreatitis (AP) patients.	18376312
Communicable Diseases, Fibrosis Assessment, Inflammation, Cell Death	Altered Intercellular Communication	Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis.	18376404
Tuberculosis, Pulmonary, Inflammation, Acidosis, Respiratory	Altered Intercellular Communication	[Comparison of systemic manifestations of inflammation in torpid pulmonary tuberculosis and respiratory sarcoidosis].	18376473
RETINOSCHISIS 1, X-LINKED, JUVENILE, Communicable Diseases, Inflammation, Tuberculosis	Altered Intercellular Communication	In tuberculosis, all detected changes may give the impression that they are secondary to tuberculous infection and, in RS, act as primary triggers in the development ofgranulomatous inflammation.	18376473
Inflammation, Pleurisy	Altered Intercellular Communication	The the pleural exudate concentrations of gamma-IFN were over 300 pg/ml (mean 1019 +/- 161 pg/ml) in 19 out of 21 patients with exudative pleuritis in a phase of active inflammation.	18376474
Inflammation, Adult Medulloblastoma, Neoplasms	Altered Intercellular Communication	Postoperative hemicerebellar inflammation mimicking recurrent tumor after resection of a medulloblastoma.	18377311
Inflammation	Altered Intercellular Communication	Postoperative hemicerebellar inflammation seemed to be the most likely explanation.	18377311
Adult Medulloblastoma, Acute inflammation, Neoplasms	Altered Intercellular Communication	This case illustrates that early postoperative inflammation can mimic recurrent tumor on MR images obtained after resection of a medulloblastoma and caution should be taken in interpreting such images.	18377311
Inflammation, Hemorrhage, Parasitic Diseases, Traumatic injury, Subarachnoid Route of Drug Administration	Altered Intercellular Communication	Acquired intradural arachnoid cystic lesions of the spine have been associated with trauma, hemorrhage, parasitic infections, and other insults that cause inflammation and subarachnoid adhesions.	18377326
Inflammation, Hypertension, CTCAE, Obesity	Altered Intercellular Communication	The association between obesity and hypertension was positive and direct (B=0.43, p<0.01) without the intermediation of inflammation or insulin resistance.	18378435
Inflammation, Necrosis	Altered Intercellular Communication	The zmpB complementation strain of NTUH-p15 significantly restored the level of inflammation and caused lung necrosis.	18379252
Communicable Diseases, Inflammation	Altered Intercellular Communication	Moreover if In-Biotin uptake is due only to high proliferation rate of bacteria presents in site of infection, it will be further investigated to discriminate definitely bacterial from sterile inflammation.	18379389
Inflammation	Altered Intercellular Communication	Acute and chronic inflammation was present in 28 cases, moderate in 15, and mild in 13 cases.	18379418
Inflammation	Altered Intercellular Communication	Eleven cases showed chronic inflammation, mild in 10, and moderate in 1 case.	18379418
Inflammation	Altered Intercellular Communication	Mesh-associated inflammation may preclude adequate nodal sampling.	18379718
Inflammation, Actinomycosis	Altered Intercellular Communication	Histopathological examination showed chronic-fibrosing and granulocytic, abscess-forming inflammation with Gram- and PAS-positive bacteria, corresponding to the diagnosis of chronic actinomycosis (Figure 1c).	18379724
Opportunistic Infections, Whipple Disease, Orbital Pseudotumor	Altered Intercellular Communication	To describe a recurrent case of idiopathic orbital inflammation (OI) associated with Whipple disease.	18379941
Opportunistic Infections, Myositis, CTCAE 5.0, Orbital Pseudotumor	Altered Intercellular Communication	A 63-year-old woman developed myositis or idiopathic orbital inflammation (OI).	18379941
Neoplasms	Altered Intercellular Communication	Consequently, such tumors may escape detection by the dermatologist and be mistaken by the gynecologist for an inflammatory condition.	18380212
Pain Distress Question, Inflammation, Neoplasms, Infection, Anemia, Sickle Cell	Altered Intercellular Communication	Various causes of back pain in children can be distinguished: mechanical problems, infections of the lumbar spine, neoplasia, inflammation, and other causes, such as sickle cell disease.	18380379
Gingivitis, Hemorrhage, Calculi, Dental Plaque	Altered Intercellular Communication	Periodontal status was evaluated by measuring probing depth (PD), clinical attachment level (CAL), plaque, bleeding on probing, visual gingival inflammation, and calculus.	18380555
Inflammatory dermatosis	Altered Intercellular Communication	Lipomatous metaplasia after severe and chronic cutaneous inflammation.	18382104
Lipomatous Metaplasia, Inflammation	Altered Intercellular Communication	We diagnosed a lipomatous metaplasia of the dermis and hypothesize that this metaplasia occurred as a consequence of the severe and chronic inflammation of the skin.	18382104
Tissue damage, Inflammation	Altered Intercellular Communication	Minimal tissue damage, mild astrocytosis, and mild inflammation surrounding the electrode termination site were observed.	18382294
Inflammation	Altered Intercellular Communication	A comparison with control tissue showed no significant difference other than mild inflammation along the lead track.	18382294
Inflammation	Altered Intercellular Communication	Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an enzyme involved in inflammation and platelet function.	18383322
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Validity, reproducibility, and responsiveness of a twelve-joint simplified power doppler ultrasonographic assessment of joint inflammation in rheumatoid arthritis.	18383408
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To investigate the validity, reproducibility, and responsiveness of a simplified power Doppler ultrasound (PDUS) assessment of joint inflammation compared with a comprehensive 44-joint PDUS assessment in patients with rheumatoid arthritis (RA) who started therapy with a biologic agent.	18383408
Arthritis	Altered Intercellular Communication	A 12-joint PDUS assessment of RA joint inflammation may be a valid, feasible method for multicenter monitoring of therapeutic response to biologic agents.	18383408
Inflammation, Obstruction	Altered Intercellular Communication	The association with incompressibility may be mediated by systemic inflammation and/or glucocorticoids, but that with obstruction is independent of a wide array of potential confounders.	18383416
Inflammation, Malignant neoplasm of endometrium, Obesity	Altered Intercellular Communication	C-reactive protein (CRP) is the most recognized biologic marker of chronic systematic inflammation, and it is conceivable that the CRP gene may work together with obesity in the development of endometrial cancer.	18383516
Pharyngitis, Ear Inflammation	Altered Intercellular Communication	The study was performed on 27 subjects (mean age 62 +/- 2.2 years, range: 28-88) with chronic catarrhalis otitis, chronic rhino-sinusitis and pharyngeal inflammation.	18383751
Inflammation, Squamous cell carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Stromal derived factor-1 (SDF-1), a protein related to angiogenesis and inflammation, has been correlated with the progression of a number of malignancies, but not with oral squamous cell carcinoma.	18383856
Inflammation, Primary malignant neoplasm, Thrombosis, Malignant Neoplasms	Altered Intercellular Communication	In light of the known contribution to the development of oral cancer of other gene polymorphisms for proteins responsible for angiogenesis, inflammation and thrombosis, this study investigated whether the G801A polymorphism in the SDF-1 gene is associated with this malignancy.	18383856
Inflammation, Lip and Oral Cavity Carcinoma	Altered Intercellular Communication	These findings suggest that the high expression G allele of the -1082A/G polymorphism of the inflammation and angiogenesis-related IL-10 is strongly associated with increased risk for oral cancer.	18383862
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Inflammation appears to be involved in the pathogenesis of PCa.	18383875
Inflammation, Tuberculosis, Malignant Neoplasms	Altered Intercellular Communication	Histopathological evaluation (143 specimens) revealed tuberculosis in 42 (mostly small bowel), malignancy in 8, and inflammation in the rest.	18384000
Inflammation	Altered Intercellular Communication	These data suggest that increased volumes of GCF and PICF could be useful markers of early inflammation in gingival and peri-implant tissues.	18384390
airway disease, Inflammation	Altered Intercellular Communication	Local inflammation in airway diseases is well recognised, but less is known about the association between low-grade systemic inflammatory processes and lung function.	18385179
airway disease, Inflammation	Altered Intercellular Communication	Applying a Mendelian randomisation approach, the study supports a causal association between low-grade general inflammation and airway diseases.	18385179
AVP gene, Panhypopituitarism	Altered Intercellular Communication	Hormonal examination showed that he had panhypopituitarism and central diabetes insipidus.	18385528
Inflammation, Atherosclerosis	Altered Intercellular Communication	Cyclooxygenase (COX) catalyzes formation of prostaglandins that contribute to the inflammation in atherosclerosis.	18385811
Granulomatous inflammation, Neoplasms, Necrosis	Altered Intercellular Communication	The tumor biopsy revealed a necrotic, granulomatous inflammation.	18385915
Inflammation	Altered Intercellular Communication	Increased emphasis on management of inflammation in conjunction with the infectious process may have contributed to the improved outcomes.	18385946
Inflammation, Ischemic stroke	Altered Intercellular Communication	Evaluation of granulocyte elastase as a sensitive diagnostic parameter of inflammation in first ischemic stroke.	18386609
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Plasma PMN elastase may be a well-characterised and sensitive inflammation marker, and it is associated with endothelial dysfunction.	18386609
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Subclinical inflammation has been suggested as a possible connective mechanism between glycoregulation disorders and NAFLD.	18386618
Granulomatous inflammation, Noncommunicable Diseases	Altered Intercellular Communication	Granulomatous inflammation with multinucleated giant cells is observed in various infectious and noninfectious diseases.	18387998
Inflammation	Altered Intercellular Communication	The results of the present study showed that oxidative stress promotes large-vessel disease rather than small-vessel disease stroke, and inflammation may play important an role in the development of small-vessel disease stroke.	18388043
malignant disease, Inflammation, Sore Throat	Altered Intercellular Communication	The pharyngeal pain is usually caused by an inflammation or a malignant disease.	18388102
Inflammation	Altered Intercellular Communication	The histopathology of the specimen obtained surgically showed non-specific inflammation in both cases.	18389286
Inflammation, Obesity, Abdominal, Hypertension, CTCAE	Altered Intercellular Communication	Abdominal obesity and inflammation predicts hypertension among prehypertensive men and women: the ATTICA Study.	18389333
Inflammation, Obesity, Abdominal, Hypertension, CTCAE	Altered Intercellular Communication	Older people, with low education, abdominal obesity, lower adherence to the Mediterranean diet, and increased inflammation, constitute a model of prehypertensive individuals that are prone to develop hypertension.	18389333
Refractory anemias, Inflammation	Altered Intercellular Communication	In RA, patients with active inflammation had an increased percentage of IL-4+ CD8+ T cells.	18390584
Arthritis	Altered Intercellular Communication	Expansion of IL-4+ CD8+ T cells, which may include precursors of a regulatory CD8+ T cell subset, may represent a general response to chronic joint inflammation.	18390584
Pain Distress Question, Inflammation, Bursitis	Altered Intercellular Communication	Previously, the etiology of the trochanteric pain syndrome was thought to be caused by inflammation of the subgluteus maximus bursa (i.e., bursitis).	18391676
Bursitis	Altered Intercellular Communication	The results of this small prospective observational histologic study, along with recent MRI and ultrasound studies on the topic, strongly suggest that there is no etiologic role of bursal inflammation in the trochanteric pain syndrome.	18391676
Inflammation	Altered Intercellular Communication	The involvement of mononuclear cells and of chronic systemic inflammation has been suggested by analysis of pathological specimens.	18392329
Inflammation, Blood Clot, Restenosis	Altered Intercellular Communication	We hypothesized that restenosis after coronary stenting is predicted by elevated levels of markers of thrombus formation and inflammation.	18392332
Inflammation, Thrombosis, Restenosis	Altered Intercellular Communication	In conclusion, the process of inflammation and thrombosis occurring after coronary interventions seems to be prolonged and enhanced in patients with high-grade restenosis at the follow up.	18392332
Inflammation, Malnutrition, Vascular calcification, Atherosclerosis, Anemia	Altered Intercellular Communication	Inflammation has a role in the genesis of accelerated atherosclerosis, vascular calcification, malnutrition and anemia, and a huge impact on the survival of these patients.	18392382
Inflammation, Neoplasms	Altered Intercellular Communication	COX-2 expression was correlated only with enhanced tumor inflammation (p = 0.03) and with tumor volume exceeding 30 cc (p = 0.05).	18392637
Inflammation, Carcinoma	Altered Intercellular Communication	A carcinoma at early stages or one hidden by acute or chronic inflammation can be overlooked during surgery, and the diagnosis would then be made only after microscopic examination of paraffin-embedded tissue.	18392708
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The surrounding pancreatic tissue showed fibrosis and chronic inflammation.	18392724
Inflammation, Xanthogranulomatous cholecystitis	Altered Intercellular Communication	These findings suggested a xanthogranulomatous inflammation, and resulted in a diagnosis of xanthogranulomatous pancreatitis.	18392724
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Lipocalin-2 (also known as neutrophil gelatinase-associated lipocalin [NGAL]) has been described as a promising marker of metabolic syndrome associated with inflammation.	18393169
Primary malignant neoplasm, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Our findings seem to confirm that cytokine genetic variants might contribute to determining the background for inflammaging in which H. pylori infection might facilitate cancer development.	18393655
Communicable Diseases, Stomach Carcinoma, Chronic gastritis	Altered Intercellular Communication	To evaluate the role of interaction of Hp infection with genetic background, gastric cancer and chronic gastritis patients as well as random selected controls were typed for five inflammation-related polymorphisms of IL-1 and IL-10 cytokine genes.	18393655
Inflammation, Intermittent	Altered Intercellular Communication	A 48-year-old female with history of nasal and auricular pain and inflammation developed bilateral intermittent scleritis that was refractory to several immunosuppressive medications.	18393953
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation in obese and nonobese patients with difficult-to-treat asthma.	18394131
Airway structure, Asthma, Obesity	Altered Intercellular Communication	This suggests that other factors than airway inflammation alone explain the relationship between obesity and asthma severity.	18394131
Tendinosis, Disorder of tendon	Altered Intercellular Communication	Nerve signal substances, such as the tachykinin substance P (SP), may be involved in the changes that occur in response to tendinopathy (tendinosis).	18394729
Dental Plaque	Altered Intercellular Communication	PET-FDG and USPIO-enhanced MRI are increasingly being used in depicting carotid atheroma inflammation--a risk factor for the high risk plaque.	18396074
Inflammation	Altered Intercellular Communication	The two imaging modalities, which identify inflammatory activity, may be potential surrogate risk markers in the selection of patients eligible for carotid surgery, if plaque inflammation can be correlated with risk of developing clinical symptoms.	18396074
Inflammation, Nasal Polyps	Altered Intercellular Communication	The observations indicate that GR-alpha may play the major role in the inflammation associated with nasal polyps and the ratio of the expression level of GR-beta to that of GR-alpha may serve as a useful index of the clinical efficacy of GC treatment.	18396779
Inflammation, Reperfusion Injury	Altered Intercellular Communication	Ischemia-reperfusion injury and inflammation in cardiac surgical patients involves complex humoral and cellular interactions.	18396798
Swelling, Neoplasms, Inflammatory abnormality of the eye	Altered Intercellular Communication	Clinically, the tumours infiltrated both eyelids on one side of the face with swelling and periocular inflammation, creating a monocle-like appearance.	18397469
Inflammation	Altered Intercellular Communication	Severe suppurative inflammation was observed throughout the bladder wall.	18397723
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	In the salivary glands of patients with primary Sjogren Syndrome (pSjS) an accumulation of dendritic cells (DCs) is seen, which is thought to play a role in stimulating local inflammation.	18397959
Parathyroid hyperplasia	Altered Intercellular Communication	Increased parathyroid hormone (PTH) synthesis and secretion is associated with parathyroid cell hyperplasia.	18398016
Airway structure, ARCN1 gene	Altered Intercellular Communication	The results showing that annual changes in airway thickening correlated with annual decline in air flow limitation suggests the importance of treatment of airway inflammation in COPD.	18399859
Airway structure, Asthma	Altered Intercellular Communication	Monitoring airway inflammation in children with asthma using FeNO or sp-Eos is clinically useful in guiding ICS dose reduction in a non-Western outpatient setting.	18399863
Inflammation	Altered Intercellular Communication	These differences do not appear to be related to diet and do not correlate with histological severity of pouch inflammation.	18400037
Neurodegenerative Disorders, Inflammation, Presenile dementia, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Evidence has been accumulating for a role of inflammation in the development of Alzheimer's disease (AD), a progressive neurodegenerative disorder causing a common form of dementia in the elderly.	18400300
Malnutrition, Chronic inflammation, Atherosclerosis, Dyslipidemias, Cessation of life	Altered Intercellular Communication	Atherosclerotic cardiovascular disease is the most common cause of death among hemodialysis patients; it has been attributed to increased oxidative stress, dyslipidemia, malnutrition, and chronic inflammation.	18400731
Inflammation, Depression, CTCAE, Coronary heart disease	Altered Intercellular Communication	Analysis of potential predictors of depression among coronary heart disease risk factors including heart rate variability, markers of inflammation, and endothelial function.	18400765
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Excess mortality due to interaction between protein-energy wasting, inflammation and cardiovascular disease in chronic dialysis patients.	18400817
Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cachexia	Altered Intercellular Communication	Protein-energy wasting (PEW), inflammation and cardiovascular diseases (CVD) clearly contribute to the high mortality in chronic dialysis.	18400817
Inflammation	Altered Intercellular Communication	Of all patients, 10% only suffered from PEW (1-5 on the 7-point subjective global assessment), 11% from inflammation (CRP >/=10 mg/L), 14% from CVD and 22% had any combination of two components.	18400817
Inflammation	Altered Intercellular Communication	Patients with either PEW (HR: 1.6, 95% CI: 1.3-2.0), inflammation (1.6, 1.3-2.0) or CVD (1.7, 1.4-2.1) had an increased mortality risk.	18400817
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	The concurrent presence of PEW, inflammation and CVD increased the mortality risk strikingly more than expected, implying that PEW interacts with inflammation and CVD in dialysis patients.	18400817
Inflammation, Atherosclerosis	Altered Intercellular Communication	Correlations of sialic acid with markers of inflammation, atherosclerosis and cardiovascular events in hemodialysis patients.	18401156
HD Term Type, Inflammation, Atherosclerosis	Altered Intercellular Communication	Serum TSA seems to correlate with inflammation, accelerated atherosclerosis and CV events in nondiabetic HD patients, but more studies need to confirm our findings.	18401156
Ischemia, Hemorrhage, Inflammation, Colonic Stenosis	Altered Intercellular Communication	Colonic anastomotic strictures are usually secondary to ischemia, leakage, inflammation, or hemorrhage at the anastomotic line.	18402122
Granulomatous inflammation, Mediastinal lymph node group, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	On autopsy, she was found to have tuberculous myocarditis with granulomatous inflammation only in the liver and without pulmonary or mediastinal lymph node involvement.	18402837
Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	eNOS expression was correlated with H. pylori infection in the mucosa of the body and antrum (P=0.013 and 0.037, respectively) but not with gastric inflammation and activity (P=0.848 and 0.871, respectively, for the corpus and P=0.565 and 0.793, respectively, for the antrum).	18403947
Gastritis	Altered Intercellular Communication	CD34 expression was correlated with gastric inflammation and activity (P=0.03 and 0.044, respectively) in the mucosa of the antrum of H. pylori-positive patients.	18403947
Inflammation	Altered Intercellular Communication	Low serum albumin was associated with age, medications and inflammation in men, as well as inflammation in women.	18405401
Inflammation, Blood Stasis	Altered Intercellular Communication	Inflammatory- and immune-related genes have a remarkable predominance in blood stasis syndrome gene expression profiles, which may explain the function of inflammation and immune response in the occurrence and development of blood stasis syndrome.	18405601
Optic Neuritis, Optic Neuropathy, Ischemic, Neurosyphilis, Meningitis	Altered Intercellular Communication	Cranial nerve involvements in neurosyphilis can result from nerve inflammation in basal meningitis, nerve ischemia in meningovasculitis or from compression by an adjacent gumma.	18405776
Myocardial immune cell infiltration, Inflammation, Corneal Endothelial Cell Loss	Altered Intercellular Communication	An increased stress and inflammation response indicates that endothelial damage from smoking could contribute to immune cell infiltration, while decreased growth rates reduce endothelial layer repair, promoting atherogenesis.	18405900
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Exacerbation	Altered Intercellular Communication	To investigate the value of C-reactive protein (CRP) as a marker of chronic obstructive pulmonary disease (COPD) exacerbations or specifically bacterial exacerbations and to evaluate a correlation between raised CRP levels and other markers of inflammation in patients with an acute exacerbation (AECOPD).	18408388
Inflammation, Malnutrition, Atherosclerosis, Depression, CTCAE, Choline Dehydrogenase, Mitochondrial, Fluid overload	Altered Intercellular Communication	The results show that lesser degrees of nocturnal dip and eLVH are associated with increased degrees of depression, implying that hypervolemia is strongly associated with depression and might be a component of strong relationships involving malnutrition, inflammation, and atherosclerosis in CHD patients.	18409016
Inflammation, Antiphospholipid Antibodies, Thrombophilia	Altered Intercellular Communication	To investigate the plasma levels and prevalence of the most common antiphospholipid antibodies, as well as their relationships with several plasma markers of inflammation, in order to characterize some aspects of cancer thrombophilia.	18409148
Refractory anemias, Inflammation, bone destruction	Altered Intercellular Communication	This study was undertaken to examine the significance of serum TRACP isoforms 5a and 5b as disease markers of inflammation and bone destruction in RA.	18410226
Cessation of life, Inflammation, Malnutrition	Altered Intercellular Communication	Biomarkers of inflammation and malnutrition associated with early death in healthy elderly people.	18410327
Inflammation, Primary malignant neoplasm, Malnutrition	Altered Intercellular Communication	To determine whether malnutrition and biomarkers of inflammation predict all-cause, cancer, and cardiovascular mortality in healthy elderly subjects.	18410327
Inflammation, Malnutrition	Altered Intercellular Communication	Biomarkers of inflammation and malnutrition together predict early mortality.	18410327
Inflammation, Obesity	Altered Intercellular Communication	We examined whether vitamin D status and obesity are associated with low-grade systemic inflammation, as assessed by serum concentrations of C-reactive protein (CRP) in an adult population of kidney-transplant patients.	18410886
Infarction, Inflammation, Malignant Atrophic Papulosis	Altered Intercellular Communication	A biopsy of one of these lesions revealed superficial and deep dermal lymphohistiocytic inflammation, mainly perivascular with a central zone of infarction consistent with Degos' disease.	18412807
Inflammation, PDR gene, Diabetic Retinopathy, diabetic	Altered Intercellular Communication	The association between TNF-alpha and PDR in type 1 diabetic patients suggests that inflammation might play a role in the pathogenesis of proliferative diabetic retinopathy.	18413212
Inflammation, Seizures, Communicable Diseases, Focal Neurologic Deficits, Brain Diseases	Altered Intercellular Communication	Patients with seizures, focal neurologic deficits, signs of local or systemic infection or inflammation, known brain disease, or any kind of previous cerebral treatment were excluded.	18413396
Inflammation	Altered Intercellular Communication	Biopsies obtained during esophagogastroduodenoscopy and colonoscopy showed acute and chronic inflammation.	18414178
Deficit, Thyroid stimulating hormone measurement	Altered Intercellular Communication	Eight patients had new hormonal deficits post-operatively (1 ACTH, 3 TSH, 2 ACTH/TSH, 2 vasopressin).	18414774
Autoimmune Diseases, Inflammation, Dermatomyositis, Childhood Type	Altered Intercellular Communication	Juvenile dermatomyositis (JDM) is a rare autoimmune disease characterized by inflammation of the muscle, connective tissue, skin, gastrointestinal tract, and small nerves.	18414893
ARCN1 gene, Inflammation	Altered Intercellular Communication	Effects of inhaled budesonide in COPD are not restricted to patients with severe disease and may be linked to a suppression of eosinophilic inflammation.	18415808
Chronic inflammation of orbit, Graves Disease, Neoplasms	Altered Intercellular Communication	Thirteen cases involved tumors (31% benign and 69% malignant), two cases presented with chronic orbital inflammation and one patient had intraorbital tissue growth secondary to Graves disease.	18415869
Inflammation	Altered Intercellular Communication	Histopathological examination confirmed focal necrotising acute inflammation with the presence of colonies of the organism in the deep substance of the implant.	18415874
Inflammation, Hashimoto Disease, Autoimmune endocrine disease, Haiti, Graves Disease	Altered Intercellular Communication	Chemokines are a group of small proteins that recruit different leukocyte subtypes to sites of inflammation and play important roles in initiating and maintaining immunological responses in autoimmune endocrine diseases including Graves' disease (GD) and Hashimoto's thyroiditis (HT).	18415893
Degenerative polyarthritis, Pain Distress Question, Inflammation, Refractory anemias	Altered Intercellular Communication	Our data predict that the cannabinoid receptor system present in the synovium may be an important therapeutic target for the treatment of pain and inflammation associated with OA and RA.	18416822
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Raisins are a significant source of dietary fiber and polyphenols, which may reduce cardiovascular disease (CVD) risk by affecting lipoprotein metabolism and inflammation.	18416823
Juvenile arthritis, Inflammation	Altered Intercellular Communication	Children with joint pain/stiffness but normal ESR had longer delays suggesting that if blood tests do not indicate inflammation, the diagnosis of JIA may be overlooked.	18417527
Diabetic Nephropathy, Calcification of coronary artery, Chronic Kidney Diseases, parathyroid hormone	Altered Intercellular Communication	This study sought to test the hypothesis that the prevalence of 25-hydroxyvitamin D deficiency is significantly higher in chronic kidney disease patients and, in diabetic nephropathy, low serum 25-hydroxyvitamin D is associated with abnormal serum parathyroid hormone, bone mineral density, and coronary artery calcification.	18417740
Inflammation	Altered Intercellular Communication	Accordingly, an association between impaired cardiac parasympathetic function, as assessed by heart rate variability (HRV), and increased markers of inflammation has recently been reported.	18418007
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor-alpha, interleukin-6 and C-reactive protein serum levels were measured, as markers of inflammation, at the same times.	18418007
Inflammation, Epilepsy, Cardiovascular Diseases	Altered Intercellular Communication	Our data in epileptic patients without cardiovascular disease failed to show a significant effect of left VNS on cardiac autonomic function and on systemic inflammation at short-term follow-up.	18418007
Pustular, Inflammation, Fever	Altered Intercellular Communication	Six days later, she exhibited inflammation of the submaxillary and parotid salivary glands, followed by an erythematous, oedematous, pustular and febrile eruption, with failure of antibiotic therapy.	18420076
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Cystic fibrosis (CF) is characterized by chronic inflammation with increased oxidative stress.	18420468
Inflammation	Altered Intercellular Communication	Endogenous glucocorticoid production in the joint is likely to have an impact on local inflammation and bone integrity.	18420938
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Necrosis	Altered Intercellular Communication	Defective efferocytosis (phagocytic clearance of apoptotic cells) in the airway may perpetuate inflammation via secondary necrosis in chronic obstructive pulmonary disease (COPD).	18420960
Inflammation	Altered Intercellular Communication	Adipose tissue inflammation may play a critical role in the pathogenesis of insulin resistance (IR).	18420999
Inflammation	Altered Intercellular Communication	Proinflammatory T-lymphocytes are present in visceral adipose tissue and may contribute to local inflammatory cell activation before the appearance of macrophages, suggesting that these cells could play an important role in the initiation and perpetuation of adipose tissue inflammation as well as the development of IR.	18420999
Inflammation, Carotid Stenosis	Altered Intercellular Communication	Markers of inflammation in patients with symptomatic and asymptomatic carotid artery stenosis: a case-control study.	18421029
Inflammation, Atherosclerosis	Altered Intercellular Communication	There is evidence that inflammation plays a role in the pathogenesis of atherosclerosis.	18421029
Inflammation, Thyrotoxicosis, Liver Dysfunction	Altered Intercellular Communication	Before treatment, most of the abnormal laboratory findings associated with thyrotoxicosis, inflammation, and liver dysfunction reached peak levels within 1 week after onset.	18421188
Kidney Failure, Chronic, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cachexia	Altered Intercellular Communication	We have investigated the relationship between bone mineral density (BMD) and inflammation, wasting, CVD and mortality in ESRD patients.	18421213
Inflammatory abnormality of the eye	Altered Intercellular Communication	Humanized models of ocular inflammation developed in HLA class I and class II transgenic mice will help better understand the mechanisms responsible for ocular inflammation.	18421235
Inflammation, NCI CTEP SDC Gastroesophageal Cancer Sub-Category Terminology	Altered Intercellular Communication	Paraoxonase 1 (PON1) status in gastroesophageal malignancies and associated paraneoplastic syndromes - connection with inflammation.	18423402
Inflammation, Anemia, NCI CTEP SDC Gastroesophageal Cancer Sub-Category Terminology	Altered Intercellular Communication	PON1 activity decreases in gastroesophageal cancers and corresponds to inflammation severity and cancer-related anemia.	18423402
Meningitis	Altered Intercellular Communication	The histopathology findings suggested a nonspecific meningeal inflammation.	18423532
Inflammation, Restenosis	Altered Intercellular Communication	An essential transcription factor for inflammation, nuclear factor-kappa B (NF-kappaB), plays a pivotal role for restenosis after percutaneous coronary intervention (PCI).	18425985
Fracture	Altered Intercellular Communication	A 73-year-old man had the clinical stigmata of graft versus host response to a cadaveric femoral-tibioperoneal graft and suspected inflammation-induced stent corrosion culminating in fracture.	18426266
Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Impact of metformin versus repaglinide on non-glycaemic cardiovascular risk markers related to inflammation and endothelial dysfunction in non-obese patients with type 2 diabetes.	18426821
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Endothelial dysfunction, Cardiovascular Diseases	Altered Intercellular Communication	In patients with type 2 diabetes mellitus (T2DM), biomarkers reflecting inflammation and endothelial dysfunction have been linked to cardiovascular disease (CVD biomarkers) and metabolic regulation.	18426821
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	In non-obese T2DM patients, metformin was more effective in reducing selected biomarkers reflecting inflammation and endothelial dysfunction compared with repaglinide despite similar glycaemic levels between treatments.	18426821
Rheumatoid Arthritis, Inflammation, Atherosclerosis	Altered Intercellular Communication	In view of the similarities between atherosclerosis and rheumatoid arthritis and the proven benefit of angiotensin-converting enzyme inhibitors in atherosclerotic vascular disease, it was the aim of the present study to delineate the impact of ramipril on endothelial function as well as on markers of inflammation and oxidative stress in patients with rheumatoid arthritis.	18427133
Inflammation	Altered Intercellular Communication	Plasmapheresis promotes normalization of hemostasis, microcirculation and immune parameters, reduction of intoxication and systemic inflammation syndrome.	18427485
Inflammation, Giant cell transformation, Fibrosis Assessment, Cholestasis, Extramedullary Hematopoiesis Function	Altered Intercellular Communication	Further, we evaluated cholestasis, portal fibrosis (PF), portal inflammation (PI), giant cell transformation (GCT), and extramedullary haematopoiesis (EMH).	18428045
Inflammation, Fulminant Hepatitis	Altered Intercellular Communication	Further studies could disclose the mechanism of severe inflammation of liver that finally leads to fulminant hepatitis.	18428142
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Studies of cancer risk and molecular carcinogenesis suggest a role for inflammation in cancer development and progression.	18428198
Inflammation, With intensity, Edema	Altered Intercellular Communication	Magnetic resonance imaging of the spinal cord showed significant erosion and irregularities of the odontoid apophysis, with hyperintensity of bone marrow in T2-weighted images because of edema and inflammation.	18430651
Presenile dementia, Inflammation	Altered Intercellular Communication	In the past years, the possible involvement of inflammation in the pathogenesis of dementia has been the subject of several investigations.	18430978
Small bowel bacterial overgrowth syndrome, Gastrointestinal inflammation	Altered Intercellular Communication	In our pilot study we evaluate fecal calprotectin concentrations (FCC) in patients with SIBO in order to identify a possible presence of subclinical intestinal inflammation.	18431069
Tissue damage, Inflammation, Endophthalmitis, CTCAE	Altered Intercellular Communication	HMGB1 can be released in the vitreous of eyes with endophthalmitis depending on inflammation and tissue damage.	18431589
Rupture, Inflammation, Ventricular Free Wall Rupture, Blood Clot, Pseudoaneurysm, Hemopericardium	Altered Intercellular Communication	The pseudoaneurysm is a rare cardiac pathology, in which the left ventricular free wall ruptures and the pericardium surrounds the rupture in combination with thrombus and inflammation and thus prevents the development of a hemopericardium.	18431740
Communicable Diseases, Primary malignant neoplasm, Inflammation, Pain Distress Question	Altered Intercellular Communication	Flow cytometric analysis of human P2X(7) pore activity segregates variant from common P2RX7 genotypes and may serve as a biomarker for cancer, pain, inflammation, and immune responses to infection.	18431793
Inflammation, Appendicitis, CTCAE, Yersinia infections	Altered Intercellular Communication	Sporadically the inflammation of the mesenterial lymph nodes caused by Yersinia infection suggested appendicitis.	18431916
Inflammation	Altered Intercellular Communication	ENT exam showed an inflammation of the nasal mucous without ulceration and the permeability of the nasal tracts was subnormal.	18431999
Inflammation, Abscess of abdominal wall, Neoplasms	Altered Intercellular Communication	Our patient's findings indicate that the abdominal wall abscess (so-called Schloffer tumor) resulted from persistent inflammation following the appendectomy performed 27 years previously.	18432066
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Biopsy materials were analyzed for the presence and extent of inflammation, fibrosis and changes in the smooth muscle layer using Masson's trichrome stain and immunohistochemical staining.	18432532
Inflammation, Fibrosis Assessment, Muscle hypertrophy, Differential renal function	Altered Intercellular Communication	In patients aged <12 months, preoperative differential renal function (DRF) was associated with fibrosis (F) and smooth muscle hypertrophy (SMH) [mean (SD) DRF for both F and SMH were Grade 0-1, 47.8% (6.4%); Grade 2-3, 36.2% (11.3%); p<0.05]; and change in DRF was associated with inflammation [Grade 0-1, -0.1% (4.0%); Grade 2-3, 5.8% (3.0%); p<0.05].	18432532
Inflammation, Thrombosis, atherosclerotic	Altered Intercellular Communication	Inflammation in atherosclerotic plaques makes them unstable and can cause thrombosis.	18433754
Inflammation	Altered Intercellular Communication	In this study, we tested whether inflammation characterized by macrophage infiltration can be detected by PBR binding.	18433754
Fibrosis Assessment, Perforation (observation), Acute suppurative inflammation	Altered Intercellular Communication	Concerning the histopathological diagnosis, n=76 patients (45.5 %) suffered from a submucous fibrosis bliteration, n 1 (12.6 ) from an acute purulent inflammation degree, n = 65 (38.9 ) from an ulcerative hlegmonous inflammation degree and n (3 ) from a perforation.	18435206
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Thus, low-grade inflammation may contribute to the high risk of cardiovascular disease in women with MetS.	18435780
Inflammation	Altered Intercellular Communication	However, alterations in corneal nerve morphology (nerve sprouting and thickened stromal nerves) and an increased amount of antigen-presenting cells, implicating the role of inflammation, were observed.	18436208
Sjogrens Syndrome", Hypersensitivity, Inflammatory abnormality of the eye	Altered Intercellular Communication	We hypothesize that patients with primary Sjogren's syndrome dry eye suffer from neuropathic corneal mechanical hypersensitivity induced by ocular surface inflammation.	18436208
Inflammation, Coronary heart disease	Altered Intercellular Communication	Do psychological factors affect inflammation and incident coronary heart disease: the Whitehall II Study.	18436803
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	The purpose of this study was to test whether psychological factors affect inflammation processes to an extent that increases the risk of coronary heart disease (CHD).	18436803
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Our findings suggest that psychological factors do not affect inflammation although they predict incident CHD.	18436803
Infarction, Inflammation, One Vessel Coronary Disease, White matter lesions	Altered Intercellular Communication	To clarify the role of inflammation in the pathogenesis of small vessel disease of the brain, we investigated the association between common variation in the C-reactive protein (CRP) and interleukin (IL)-6 genes, plasma CRP and IL6 levels, and presence of MRI-defined white matter lesions (WML) and brain infarcts (BI) in elderly participants of the Cardiovascular Health Study.	18436879
Inflammation, One Vessel Coronary Disease	Altered Intercellular Communication	This study provides evidence of a genetic basis underlying the relationship between plasma biomarkers of inflammation and small vessel disease of the brain.	18436879
Inflammation, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	These findings are consistent with the hypothesis that the chemokine receptor CCR5 is involved in the mediation of low-grade systemic inflammation and may play a role in human atherosclerosis and cardiovascular disease.	18436884
Inflammatory abnormality of the eye	Altered Intercellular Communication	Previously, we showed a role for VAP-1 in ocular inflammation.	18436961
Tumor necrosis	Altered Intercellular Communication	Furthermore, VAP-1 blockade significantly reduced the expression of inflammation-associated molecules such as tumor necrosis factor (TNF) -alpha, monocyte chemoattractant protein (MCP) -1, and intercellular adhesion molecule (ICAM) -1.	18436961
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	1) The pathological changes with BA are characterized by inflammation and fibrosis in the hepatic portal area.	18437653
Cholestasis, Acute inflammation, Interstitial Fibrosis Assessment	Altered Intercellular Communication	The triangular cord of porta hepatis was characterized by hyperplasia of canaliculi, atresia or stenosis of the bile ducts, inflammation infiltration, cholestasis, and interstitial fibrosis.	18437653
Biliary Atresia, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The main pathological changes of biliary atresia are inflammation and fibrosis in the hepatic portal area.	18437653
Inflammation	Altered Intercellular Communication	These data suggest that baseline inflammation influences vein graft healing, and therefore, inflammation may be a relevant therapeutic target to improve early vein graft adaptation.	18440187
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	Numerous studies demonstrate inflammatory proteins in the brain and microcirculation in Alzheimer's disease (AD) and implicate inflammation in disease pathogenesis.	18440671
Inflammation, Cholelithiasis, Cholecystitis	Altered Intercellular Communication	Estrogen exposure is a risk factor for gallstone disease (cholelithiasis), which often leads to chronic inflammation (cholecystitis).	18440760
Inflammation, Cholelithiasis	Altered Intercellular Communication	To assess whether this might also apply for gallbladder epithelia, we determined expression of these two enzymes and of ERalpha and ERbeta in 15 cholelithiasis specimens from tissues with/or without inflammation.	18440760
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	A retrospective, non-comparative interventional case series of 22 consecutive patients with syphilitic uveitis who were managed in the Ocular Inflammation and Immunology Services of the Singapore National Eye Centre between 1995 and 2006.	18441168
Inflammation, Ocular syphilis	Altered Intercellular Communication	Ocular syphilis presented most frequently as a non-granulomatous inflammation.	18441168
Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	H. pylori-infected patients with IL18 -607C/C and -137G/G have higher IL-18 levels, which causes severe gastric inflammation.	18442334
Inflammation	Altered Intercellular Communication	Two and three visible lines mean moderate (>or=10-25 mg/L) and severe (>or=25-50 mg/L) inflammations respectively while four visible lines stand for a very severe inflammation (>or=50-100 mg/L).	18442829
Inflammation	Altered Intercellular Communication	If the visible lines become faint and the intensity of the first line is weaker than that of the control line and may even disappear, this outcome corresponds to the stage of having super severe inflammation (>or=100 mg/L).	18442829
Inflammation	Altered Intercellular Communication	Two and three visible lines mean moderate (>or=10-25 mg/L) and severe (>or=25-50 mg/L) inflammations respectively while four visible lines stand for a very severe inflammation (>or=50-100 mg/L).	18442829
Inflammation, Observation Method - Coagulation, Critical Illness	Altered Intercellular Communication	There may not be any significant relationship between IR and measures of inflammation, coagulation, and clinical outcomes in a heterogeneous population of critically ill patients.	18443133
Inflammation, Diverticulitis	Altered Intercellular Communication	Mild diverticulitis is uncomplicated confined per colonic inflammation commonly treated conservatively.	18443803
Inflammation, Injury of bile duct	Altered Intercellular Communication	Is inflammation a significant predictor of bile duct injury during laparoscopic cholecystectomy?	18443865
Cholecystitis	Altered Intercellular Communication	However, there is a controversy as to whether gallbladder inflammation is a significant predictor for BDI.	18443865
Inflammation	Altered Intercellular Communication	The conversion rate was 5% and was higher among male, elder patients, and those with inflammation.	18443865
Inflammation, Traumatic injury	Altered Intercellular Communication	The BDI incidence was 0.69% (0.14% for major and 0.55% for minor injuries) and it was significantly higher in those with inflammation compared to those without inflammation (p = 0.01).	18443865
Inflammation	Altered Intercellular Communication	In particular, the risk for BDI was almost 3.5 times higher in those with inflammation (OR = 3.61, 95% CI 1.27-10.21).	18443865
Inflammation	Altered Intercellular Communication	Inflammation remained an independent risk factor for BDI even after adjustment for potential confounders.	18443865
Inflammation	Altered Intercellular Communication	No association was observed between clinical outcome and management of BDI, time of diagnosis, sex, and inflammation.	18443865
Inflammation	Altered Intercellular Communication	We revealed that inflammation is an independent predictor of BDI occurrence during LC.	18443865
Inflammation	Altered Intercellular Communication	Therefore, it would be advisable for surgeons to not hesitate to convert a LC to an OC in the presence of inflammation.	18443865
Pain Distress Question, Swelling, Inflammation	Altered Intercellular Communication	In five patients (25%) complications occurred, such as pain, inflammation and suborbital swelling and three eventually underwent a re-exploration of the surgical area, resulting in a permanent scar in one patient.	18444496
Tubular atrophy, Interstitial Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	In biopsies > or =5 months, BAT and IGT scores correlated with interstitial inflammation, tubular atrophy and interstitial fibrosis.	18444922
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	This effect may be directly anti-TNF mediated or the result of effective dampening of the inflammation in the rheumatoid joint.	18445623
Inflammation	Altered Intercellular Communication	On the diagnosis in November, 2006, physical examinations and MR images showed a remarkable inflammation at the calcaneal insertion area of Achilles tendon.	18446014
Inflammation, Low Grade Squamous Intraepithelial Neoplasia	Altered Intercellular Communication	Vaginal discharge, reactive changes, ASCUS or LSIL and moderate to severe inflammation in the cytology were significantly more common among Ct positive women (P <0.001).	18446086
Infarction, Inflammation, Thrombosis, Gross Placental Abruption	Altered Intercellular Communication	Lesions of uteroplacental circulation (abruption, extensive infarction or thrombosis, marked basal or perivillous fibrin deposition, increased syncytial knots) were inversely related to those associated with inflammation of the membranes and cord.	18446627
Inflammation, Funisitis (disorder)	Altered Intercellular Communication	Of the placentas with umbilical cord inflammation, 8% had no inflammation of the chorionic plate.	18446627
Inflammation, Vascular Diseases	Altered Intercellular Communication	Inflammation occurred frequently, but not in placentas that had characteristics of vasculopathy.	18446627
Inflammation, Vascular Diseases	Altered Intercellular Communication	The prevalence of inflammation decreased with increasing gestational age, while vasculopathy increased.	18446627
Inflammation, Funisitis (disorder)	Altered Intercellular Communication	Funisitis need not be accompanied by chorionic inflammation.	18446627
Inflammation, Atherosclerosis	Altered Intercellular Communication	Starting from these observations, recent evidences highlighted the crucial role of inflammation in the genesis of atherosclerosis.	18447179
Inflammation, Dermatomyositis, Calcinosis, Dermatomyositis, Childhood Type	Altered Intercellular Communication	Physiologically low levels of fetuin-A in young children combined with an additional negative acute-phase effect on fetuin-A due to chronic inflammation could explain in part the propensity to develop ectopic calcification observed in JDM patients, and why calcinosis is less frequent in adults with dermatomyositis.	18448482
Inflammation, Neoplasms	Altered Intercellular Communication	There is strong evidence that cancer-associated inflammation promotes tumor growth and progression.	18448485
Inflammation, Fibrosis Assessment, Liver Cirrhosis	Altered Intercellular Communication	The presence of inflammation significantly affected TE measurements in patients who did not have cirrhosis (p<0.0001), even after adjusting for the stage of fibrosis.	18448567
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Inflammation and the redox-sensitive AGE-RAGE pathway as a therapeutic target in Alzheimer's disease.	18448809
Inflammation, Data types - Address	Altered Intercellular Communication	Neuritic amyloid plaques and concomitant chronic inflammation are prominent pathological features of AD.	18448809
glycation	Altered Intercellular Communication	beta-amyloid peptide (Abeta), the major component of plaques, and advanced glycation end products (AGEs), post-translational protein modifications, are key activators of plaque-associated inflammation.	18448809
Inflammation, Data types - Address, Nerve Degeneration	Altered Intercellular Communication	RAGE-mediated inflammation caused by glial cells and subsequent changes in neuronal glucose metabolism are likely to be important contributors to neurodegeneration in AD.	18448809
Inflammation, Bacterial Infections	Altered Intercellular Communication	Although the persistence of non-healing wounds is, in part, due to prolonged chronic inflammation and bacterial infection, our investigations show that premature fibroblast aging and an inability to correctly express a stromal address code are also implicated in the disease chronicity.	18449211
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Inflammation plays a major role in coronary artery disease (CAD).	18449426
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide (eNO) is a noninvasive marker of airway inflammation.	18450114
Tooth eruption, Inflammation	Altered Intercellular Communication	There was also a trend associating gingival inflammation with expedited tooth eruption in both groups.	18450858
Inflammation	Altered Intercellular Communication	Polymorphisms of the IL1-receptor antagonist gene (IL1RN) are associated with multiple markers of systemic inflammation.	18451331
Inflammation	Altered Intercellular Communication	Common functional polymorphisms of the IL1RN gene are associated with several markers of systemic inflammation.	18451331
Granulomatous inflammation, Skin lesion	Altered Intercellular Communication	A biopsy specimen from the skin lesion revealed granulomatous inflammation with hyphae.	18451593
Paranasal Sinus Disorder, Bronchitis	Altered Intercellular Communication	Whether sinus disease directly affects the intensity of bronchial inflammation remains to be elucidated.	18451648
Acute and chronic inflammation	Altered Intercellular Communication	Nevertheless, this treatment is effective in only a part of these patients and recent studies suggested a role for other cytokines in chronic bowel inflammation.	18452203
Inflammation, Ischemic stroke	Altered Intercellular Communication	Inflammation might be related to LI, and leukocyte and monocyte counts are regarded as an inflammatory marker of ischemic stroke.	18452544
Inflammation, Atrophic iris, Acanthamoeba, Cataract, Glaucoma, CTCAE	Altered Intercellular Communication	Cataract may occur and progress during the management of Acanthamoeba keratitis in association with anterior segment inflammation, iris atrophy, and secondary glaucoma.	18452764
Inflammation, Albuminuria, Obesity, Congestive heart failure	Altered Intercellular Communication	Recently, increasing interest has emerged on the potential role of novel risk factors such as systemic inflammation, insulin resistance, and albuminuria in the pathophysiology of CHF and their relationship with obesity.	18452784
Inflammation, Obesity, Congestive heart failure	Altered Intercellular Communication	The association of obesity and CHF may be related to pathophysiologic pathways associated with inflammation.	18452784
Communicable Diseases, Pancreatitis, Inflammation, Necrosis	Altered Intercellular Communication	At destructive pancreatitis of other origin in a stage of the infection or necrotic suppurative inflammation use of open and closed small invasive methods of intervention is most proved.	18454103
Inflammation	Altered Intercellular Communication	A 86-year-old woman developed a unilateral severe anterior chamber inflammation associated with descemtic folds after direct contact with sap of Euphorbia.	18454396
Intraocular inflammation, Traumatic injury	Altered Intercellular Communication	The patient noticed decreased central vision in his left eye since 5 days without any history of trauma or intraocular inflammation.	18454404
Myositis, CTCAE 5.0, Orbital Pseudotumor	Altered Intercellular Communication	Isolated lateral rectus myositis as a manifestation of idiopathic orbital inflammation.	18454414
Myositis, CTCAE 5.0, Orbital Pseudotumor	Altered Intercellular Communication	We report the case of of a patient with isolated, acute, monolateral and monomuscular lateral rectus myositis as a manifestation of a localized, nonspecific, idiopathic orbital inflammation.	18454414
Myositis, CTCAE 5.0, Orbital Pseudotumor	Altered Intercellular Communication	A monocular, monomuscular myositis as a clinical manifestation of idiopathic orbital inflammation was diagnosed by the clinical findings and imaging with orbital CT/MRI scans.	18454414
Myositis, CTCAE 5.0, Orbital Pseudotumor	Altered Intercellular Communication	Isolated lateral rectus myositis can be a manifestation of idiopathic orbital inflammation.	18454414
Inflammation, Periodontal Route of Administration	Altered Intercellular Communication	Matrix metalloproteinases (MMPs) are a family of host-derived proteinases reported to mediate multiple functions associated with periodontal destruction and inflammation.	18454660
Inflammation	Altered Intercellular Communication	The purpose of this study was to determine whether SDF-1alpha secreted by host cells plays a role in recruiting inflammatory cells into the periodontia during local inflammation.	18454663
Inflammation	Altered Intercellular Communication	Upon the development of diseased tissues, SDF-1alpha levels increase and may recruit host defensive cells into sites of inflammation.	18454663
Disability, Inflammation	Altered Intercellular Communication	Inflammation and disability as risk factors for mortality in elderly acute care patients.	18456352
Inflammation	Altered Intercellular Communication	Although the role of inflammation has been studied in specific diseases or in community living elderly, data in hospitalized acute care elderly patients are scarce.	18456352
Cessation of life, Inflammation, Malnutrition, Ulcer	Altered Intercellular Communication	Univariate analysis revealed that disability, no anti-depressant drug, pressure ulcers, a higher number of associated conditions, living with another person, and biological markers of malnutrition (albumin <35g/l, transthyretin <200mg/l) and inflammation (CRP < or =30mg/l, orosomucoid > or =1.25g/l) were significantly associated with an increase in the risk of death.	18456352
Delirium, Inflammation, septic, Sepsis-Associated Delirium	Altered Intercellular Communication	We tested the hypothesis that cerebral perfusion and selected serum markers of inflammation and delirium differ in septic patients with and without sepsis-associated delirium.	18457586
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Age greater than 30 years (P=0.035), grade 2 liver inflammation (P=0.005), and lower serum HBV DNA level (mean 7.45 vs. 8.42 log10 copies/mL, P<0.001) were independently associated with stage 2 fibrosis on liver biopsy.	18458642
Inflammation	Altered Intercellular Communication	In acute inflammation ADC values were higher before [1.22 x 10(-3) mm(2)/s (p=0.006)] and after stimulation [1.32 x 10(-3) mm(2)/s (p<0.001)].	18458907
Inflammation	Altered Intercellular Communication	Before stimulation ADC differences between chronic inflammation (1.05 x 10(-3) mm(2)/s) and healthy volunteers (p=0.04) as well as between acute and chronic inflammation (p=0.005) were statistically significant.	18458907
Inflammation	Altered Intercellular Communication	No differences were detected after stimulation between chronic inflammation (1.2 x 10(-3) mm(2)/s) and healthy volunteers (p=0.94) and between acute and chronic inflammation (p=0.15), respectively.	18458907
Inflammation	Altered Intercellular Communication	DW-EPI seems to display the physiological changes of the parotid gland in patients suffering from acute or chronic inflammation and might be useful for discriminating healthy from affected glands.	18458907
Inflammation, Steatohepatitis, Fibrosis Assessment, Balloon Dilatation, Fatty Liver Disease	Altered Intercellular Communication	Histopathology factors of hepatic steatosis (P = 0.012), ballooning degeneration (P = 0.001), lobular inflammation (P = 0.019), fibrosis (P = 0.026), and glycogenated nuclei (P = 0.028) were significantly different between NASH and GD groups.	18459024
HIV Antigens, HIV Infections	Altered Intercellular Communication	Because HIV-associated damage to cells of the CNS involves dysregulation of neuronal signaling and white matter damage, we hypothesized that PINCH may play a role in neuropathological processes during the course of HIV infection.	18459134
Inflammation	Altered Intercellular Communication	To gain insight into this issue we applied the skin blister method that allows collection of in vivo transmigrated cells at sites of local inflammation.	18460014
AURKAIP1 gene, Waldenstrom Macroglobulinemia	Altered Intercellular Communication	In grade 1 and 2 AIP, macrophages and myofibroblasts expressing profibrotic cytokines and their receptors were found in periductal areas showing lymphoplasmacytic inflammation.	18460977
Fibrosis Assessment, Fatty degeneration, Hepatobiliary Disorder, Transplant-Related Malignant Neoplasm, Ear Inflammation, Fatty Liver Disease	Altered Intercellular Communication	Biopsies were classified as normal, minimal changes (eg, nonaggressive portal or lobular mononuclear inflammation, steatosis <10%), fatty liver disease, recurrent primary liver disease, and transplant-related disease (portal-based rejection or central venulitis, an inflammatory pattern that encompasses perivenular hepatocyte dropout, mononuclear inflammation, pigment-laden macrophages, and variable zone 3 fibrosis).	18460980
Inflammation, Primary malignant neoplasm, Gastrointestinal mucositis	Altered Intercellular Communication	Conceivably, mucositis may provide an "inflammation bias" that could lead to the overuse of antibiotics and growth factors in 20%-40% of patients with cancer.	18462172
Refractory anemias, Inflammation	Altered Intercellular Communication	Therefore, it is suggested that the ongoing inflammation is driven by similar mechanisms in the tenosynovium and joint synovium and that RA is probably a tissue-specific disease which targets systemic synovial tissues.	18462359
Schizophrenia	Altered Intercellular Communication	Abnormalities in glutamate neurotransmission are thought to be among the major contributing factors to the pathophysiology of schizophrenia.	18462708
Epilepsy	Altered Intercellular Communication	Presence of epilepsy, although rare in patients with 6p duplication may be linked to genes involved in brain function and synaptic transmission in the 6p21.2p22.1 duplicated region (GABBR1, BRD2 and GRM4).	18463015
Cystitis	Altered Intercellular Communication	Recent evidence supports a role for vascular endothelium growth factor (VEGF) signaling in bladder inflammation.	18463314
Inflammation	Altered Intercellular Communication	Chronic inflammation and CD16+ natural killer cell zeta-chain downregulation in hemodialysis patients.	18463433
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	NK cell zeta-chain is downregulated in patients with cancer due to chronic inflammation.	18463433
HD Term Type, Inflammation	Altered Intercellular Communication	Chronic inflammation could be responsible for the NK cell zeta- chain downregulation in HD patients, contributing to the decreased NK cell activity.	18463433
Inflammation	Altered Intercellular Communication	In the corpus biopsy specimens there was a significant relationship between the density of H. pylori colonization (P = 0.02) and chronic inflammation (P = 0.02) and cagA-positive genotypes.	18465229
Intestinal metaplasia, Inflammation, Gland	Altered Intercellular Communication	In the antrum specimens there was a significant relationship between cagA positivity and neutrophil activity (P = 0.003) and glandular atrophy (P = 0.002), but not with H. pylori density, chronic inflammation, and intestinal metaplasia.	18465229
Palate, Inflammation, Candida (fungus)	Altered Intercellular Communication	Miconazole (group Mz) neither caused significant reduction of palatal inflammation nor eradicated Candida from the dentures and palates.	18466276
Inflammation, Gastritis	Altered Intercellular Communication	The gastritis grade (the severity and topography of inflammation) was obtained by combining antral and body inflammation scores.	18466398
Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, Colitis	Altered Intercellular Communication	In addition, the 2 major forms of IBD, ulcerative colitis (UC) and Crohn's disease (CD), have overlapping nonspecific, pathologic features leading to difficulties in assessing colonic inflammation and hence the term IBD unclassified has been proposed.	18466904
Inflammation, Fibrosis Assessment, Calcinosis	Altered Intercellular Communication	Peritoneal lesions were intense in all patients with prominent HV, fibrosis, and a variable presence of inflammation, fibrin, and calcification.	18467038
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Strenuous exercise induces an initial pro- and subsequent anti-inflammatory response, and it has been suggested that this may be one of the ways that regular exercise reduces chronic inflammation and therefore the risk of cardiovascular disease.	18467550
Inflammation, Damage	Altered Intercellular Communication	Liver biopsy showed dense eosinophilic inflammation in the portal areas with bile duct damage.	18467919
Inflammation	Altered Intercellular Communication	Correlation of the severity of inflammation with the number and size of the stones.	18468414
Inflammation	Altered Intercellular Communication	According to the histopathological examination, chronic inflammation was subdivided into mild-moderate and severe.	18468414
Inflammation	Altered Intercellular Communication	Mild-moderate inflammation characterized 63.4% of the cases and severe inflammation 366%.	18468414
Inflammation	Altered Intercellular Communication	The gallbladder wall thickness was associated with the degree of inflammation (p < 0.001, Chi-square).	18468414
Inflammation, Biliary calculi	Altered Intercellular Communication	In the univariable analysis, inflammation was positively associated with the diameter of the largest gallstone (p = 0.032, Chi-square), but negatively associated with the number of gallstones (p < 0.001, Chi-square) and patients' age (p = 0.008, logistic regression).	18468414
Inflammation, Biliary calculi	Altered Intercellular Communication	In the multivariable logistic regression, the effect of age (OR = 0.95, 95% CI: 0.91-0.99) and solitary gallstones (OR = 2.66, 95% CI: 1.02-6.93) on inflammation persisted, but that of the largest gallstone diameter vanished.	18468414
Inflammation, Biliary calculi	Altered Intercellular Communication	Solitary gallstones and younger age were the most important predictors for severe inflammation.	18468414
Inflammation, Primary malignant neoplasm, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	Inflammation may be involved in the pathogenesis of atherosclerosis, type 2 diabetes mellitus, and cancer.	18469275
Inflammatory disorder	Altered Intercellular Communication	We excluded persons with life-limiting or possible inflammation-related diseases and those using analgesics.	18469275
Inflammation, atherosclerotic	Altered Intercellular Communication	Oxidative stress, inflammation, and atherosclerotic changes in retinal arteries in the Japanese population; results from the Mima study.	18469484
Inflammation	Altered Intercellular Communication	Oxidative stress and inflammation are known to play roles in the pathogenesis of vascular events.	18469484
Inflammation, Atherosclerosis	Altered Intercellular Communication	These results suggest that oxidative stress and chronic inflammation promote atherosclerosis in the retinal arteries in the general population.	18469484
Inflammation, Nasal Polyps, Allergy - Charge Type Reason, Asthma, Chronic sinusitis	Altered Intercellular Communication	Association of chronic rhinosinusitis with nasal polyps and asthma: clinical and radiological features, allergy and inflammation markers.	18469501
Inflammation, Nasal Polyps, Chronic sinusitis, Asthma	Altered Intercellular Communication	Coexistence of chronic rhinosinusitis with nasal polyps and asthma and rather similar characteristics of inflammation support assumption that chronic rhinosinusitis and nasal polyps and asthma may be, at least in part, the same disease process.	18469501
Inflammation, Nasal Polyps, Allergy - Charge Type Reason, Asthma, Chronic sinusitis	Altered Intercellular Communication	We therefore aimed to evaluate the differences of sinus radiologic findings, systemic inflammation and allergy markers, pulmonary function of chronic rhinosinusitis associated with nasal polyps and asthma.	18469501
Inflammation, Respiratory Tract Diseases, Bronchial Obstruction, Nasal Polyps, Asthma, Chronic sinusitis, IL13 gene	Altered Intercellular Communication	Our data indicate that patients with chronic rhinosinusitis compose clinically heterogeneous group and when associated with nasal polyps and asthma constitutes the most severe form of unified respiratory tract disease, which is characterized by older age of the patients, greater duration of nasal symptoms, extent of sinus radiological changes, more prominent systemic inflammation markers, greater bronchial obstruction, incidence of perennial allergic rhinitis.	18469501
Inflammation	Altered Intercellular Communication	PCT may be an early and better marker of elevated cytokines than the more classic criteria of inflammation.	18470714
Joint Subluxations, Meningitis, Bacterial, "Grisels syndrome", Atlantoaxial	Altered Intercellular Communication	The third patient was a 75-year-old woman who died as a result of acute bacterial leptomeningitis at the cervico-medullary junction with acute inflammation of the connective tissue of her upper cervical spinal column associated with subluxation of her atlantoaxial (AA) joint, also known as Grisel's syndrome.	18471225
Malnutrition	Altered Intercellular Communication	The combination of alpha-keto acid and low-protein diet can ameliorate malnutrition and micro-inflammation in CAPD patients.	18471410
Cranial nerve palsies, Intracranial Extension, Sinusitis, Osteomyelitis, Sphenoid Sinusitis	Altered Intercellular Communication	Despite antimicrobial therapy, intracranial extension progressed, including clival osteomyelitis, sphenoid sinusitis, cavernous sinus inflammation and cranial nerve palsies, until the sphenoid sinus was drained.	18472169
Gastritis, Blood Platelet Disorders, Duodenal Ulcer, Iron deficiency anemia	Altered Intercellular Communication	A 10-year-old Chinese boy who had a history of congenital thrombocytopathy presented with severe iron deficiency anemia secondary to chronic gastric inflammation and duodenal ulcerations.	18473428
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The IRIS V study: pioglitazone improves systemic chronic inflammation in patients with type 2 diabetes under daily routine conditions.	18473695
Vasculitis	Altered Intercellular Communication	The results show that pioglitazone treatment improves chronic vascular inflammation, which may be associated with reduced cardiovascular risk.	18473695
Inflammation, Obesity	Altered Intercellular Communication	Inflammation as an intermediate pathway in the association between psychosocial stress and obesity.	18474384
Inflammation	Altered Intercellular Communication	Osteopontin in the cerebrospinal fluid may be, in part, of central nervous system origin, and may play an important role in central nervous system inflammation.	18474739
Exanthema, Hepatic inflammation, Fever, CTCAE	Altered Intercellular Communication	A 5-yr-old girl developed fever, rash and hepatic inflammation after receiving phenobarbital.	18475056
Inflammation, Heart Atrium, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Subclinical inflammation and atrial strain have been recognized as important contributors to atrial fibrillation onset and perpetuation.	18475126
vascular inflammations, Blood Pressure	Altered Intercellular Communication	Vascular inflammation in absence of blood pressure elevation in transgenic murine model overexpressing endothelin-1 in endothelial cells.	18475147
vascular inflammations	Altered Intercellular Communication	To further characterize this model, the role of vascular inflammation was investigated in young male transgenic and wild-type littermate mice.	18475147
Inflammation, vascular inflammations	Altered Intercellular Communication	These findings suggest that in this murine model of endothelial cell-restricted preproendothelin-1 overexpression, endothelin-1 induces vascular inflammation by multiple pathways in young animals in the absence of blood pressure elevation or systemic inflammation.	18475147
Inflammation, Sleep Apnea Syndromes	Altered Intercellular Communication	Increased low-grade inflammation and plasminogen-activator inhibitor-1 level in nondippers with sleep apnea syndrome.	18475156
Inflammation, Hypertension, CTCAE, Dental Plaque	Altered Intercellular Communication	Data also showed that more benefit might be gained from controlling both hypertension and inflammation for preventing plaque.	18476584
Data types - Address, neuropathology disease	Altered Intercellular Communication	These findings indicate that CSF DHEA and pregnenolone levels are correlated with temporal cortex brain levels of these neurosteroids and that CSF DHEA is elevated in AD and related to neuropathological disease stage.	18477662
Data types - Address	Altered Intercellular Communication	Neurosteroids may thus be relevant to the pathophysiology of AD.	18477662
Inflammation, Cholangiocarcinoma	Altered Intercellular Communication	The resulting inflammation may contribute to malignant transformation of the biliary epithelium and therefore increase the risk of cholangiocarcinoma.	18477806
Inflammation, Infectious agent	Altered Intercellular Communication	The leading hypothesis is that telomere attrition is due to inflammation, exposure to infectious agents, and other types of oxidative stress, which damage telomeres and impair their repair mechanisms.	18478110
Airway structure, Asthma	Altered Intercellular Communication	No significant effect of pollution could be seen either on airway inflammation and oxidative stress either in healthy students or students with asthma.	18479529
Helicobacter pylori, allergic inflammation	Altered Intercellular Communication	Helicobacter pylori in allergic inflammation--fact or fiction?	18479660
allergic inflammation	Altered Intercellular Communication	In this study we aimed to determine the association between H. pylori infection and allergic inflammation.	18479660
allergic inflammation	Altered Intercellular Communication	Therefore, the eradication of H. pylori may not be assumed to have an effect on allergic inflammation.	18479660
Inflammation, Ischemic stroke	Altered Intercellular Communication	The impact of inflammation on the pathogenesis and prognosis of ischemic stroke.	18479710
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	The inflammation plays a critical role in the stroke onset and even in the worsening of the lesions.	18479710
Airway structure, Asthma	Altered Intercellular Communication	Although once-daily administration is sufficient for clinical control of asthma, it might not control airway inflammation sufficiently.	18479954
Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	It has also been documented in a variety of benign conditions, occurring in polyps and lesions associated with inflammation and ulceration.	18480393
Inflammation, Osseous metaplasia	Altered Intercellular Communication	In common with other cases, in which osseous metaplasia arises within a background of inflammation, the present case demonstrated stromal fibroblastic proliferation.	18480393
Inflammation, Asthma	Altered Intercellular Communication	We then compared differences in asthma outcomes (exacerbation frequency and change in corticosteroid dose at 12 mo) between clusters in a third population of 68 subjects with predominantly refractory asthma, clustered at entry into a randomized trial comparing a strategy of minimizing eosinophilic inflammation (inflammation-guided strategy) with standard care.	18480428
Discordance, Inflammation, Asthma, Airway structure	Altered Intercellular Communication	Two clusters characterized by marked discordance between symptom expression and eosinophilic airway inflammation (early-onset symptom predominant and late-onset inflammation predominant) were specific to refractory asthma.	18480428
Communicable Diseases, Inflammation	Altered Intercellular Communication	Because skin temperature variability could not be explained by the variables assessed, a temperature change could suggest the presence of a pathological process such as an infection or increased inflammation.	18480503
Inflammation	Altered Intercellular Communication	Clinically it occurred without severe immunosuppression, and showed characteristic aspects, with more intense inflammation and less parasite burden.	18480575
Hormone abnormality	Altered Intercellular Communication	Symptoms of these hormonal abnormalities might be subtle and thus easily ignored.	18480658
Inflammation	Altered Intercellular Communication	Circulating YKL-40 is elevated in patients with inflammation and increased tissue remodeling.	18480670
Inflammation, Renpenning syndrome 1	Altered Intercellular Communication	The association between SHS indicated by serum cotinine and markers of inflammation has not been investigated in adult workers.	18481260
Delirium	Altered Intercellular Communication	In light of the ageing/inflammation theory, we investigated the association of these markers with delirium in not acutely ill, elderly patients.	18481319
Inflammation, Communicable Diseases, Fibrosis Assessment, Fatty degeneration, Hepatitis C, Hepatitis, Chronic	Altered Intercellular Communication	Effect of steatosis and inflammation on liver fibrosis in chronic hepatitis C. The role of liver biopsy has been questioned in the management of patients with hepatitis C viral (HCV) infection.	18482270
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	In liver biopsy specimens, inflammation activity was present in 68%, increased fibrosis in 19% and marked steatosis in 17% of patients.	18482270
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Steatosis and inflammation activity were independent histological risk factors for fibrosis only in GT-1; in GT-3, only inflammation correlated independently with fibrosis.	18482270
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	When scoring liver biopsies of HCV patients, the degree of steatosis should be included in addition to fibrosis and inflammation activity.	18482270
Inflammation	Altered Intercellular Communication	Estimation of the degree of inflammation by measuring the surface temperature over the TMJ was not reliable.	18482350
Refractory Cytopenia of Childhood, Failure, Tuberculum Sellae Meningioma, Craniopharyngioma	Altered Intercellular Communication	Herein we present the rates and risk factors of new hormonal failure and recovery in patients undergoing surgery for either an RCC, craniopharyngioma, or tuberculum sella meningioma.	18482750
Refractory Cytopenia of Childhood, Craniopharyngioma, Suprasellar Meningioma	Altered Intercellular Communication	Hormonal function improves in the majority of patients undergoing drainage of an RCC but is unlikely to occur after removal of a craniopharyngioma or suprasellar meningioma.	18482750
Gastrointestinal inflammation	Altered Intercellular Communication	The role of the novel Th17 cytokine IL-26 in intestinal inflammation.	18483078
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	IL-26 modulates IEC proliferation and proinflammatory gene expression and its expression is upregulated in active Crohn's disease, indicating a role for this cytokine system in the innate host cell response during intestinal inflammation.	18483078
Airway structure	Altered Intercellular Communication	Nasal epithelial cells as surrogates for bronchial epithelial cells in airway inflammation studies.	18483420
Airway structure	Altered Intercellular Communication	However, substituting nasal cells for bronchial epithelial cells in the study of airway inflammation depends upon comparability of responses, and evidence for this is lacking.	18483420
Airway structure	Altered Intercellular Communication	Therefore, nasal epithelial cultures constitute an accessible surrogate for studying lower airway inflammation.	18483420
Inflammation, Malnutrition, palladium, diabetic, physiopathological	Altered Intercellular Communication	The significant association between each nutritional marker and PWV in PD patients was independent of inflammation and diabetic state, suggesting that malnutrition may contribute to vascular dysfunction.	18483453
Bothered by Vomiting, Disorders of Porphyrin Metabolism	Altered Intercellular Communication	Hormonal changes, prolonged fasting due to vomiting and some medications used during pregnancy, may cause an acute crisis of porphyria, sometimes unveiling a latent disease.	18483667
Inflammation, Coronary heart disease, Nephritis, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Moreover, IMR correlated weakly with age and renal parenchymal inflammation but not with peritumorous inflammation, coronary heart disease (CHD) or gender.	18483813
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Oxidative stress and inflammation are hallmarks of chronic obstructive pulmonary disease (COPD).	18484356
Inflammation, Liver diseases	Altered Intercellular Communication	Liver biopsy and the score of histopathological inflammation grading were performed in 31 patients with hepatopathy to explore the correlation between serum ASL level and hepatic histopathological change.	18484660
Inflammation	Altered Intercellular Communication	A positive correlation (r=0.417, P=0.019) was observed between serum ASL levels (86.9+/-26.5) and scores of histopathological inflammation grading (SHIG) (9.83+/-3.36).	18484660
Inflammation, Atherosclerosis	Altered Intercellular Communication	Association of adiposity, inflammation and atherosclerosis: the role of adipocytokines and CRP in Asian Indian subjects.	18484906
Inflammation, Eosinophilic inflammation	Altered Intercellular Communication	Microscopically, the bladder tissue at 1 month after BCG injection showed marked acute and chronic inflammation with eosinophilic infiltration and focal granulomatous formation.	18485037
Inflammation	Altered Intercellular Communication	At 2 months after BoNT-A injection, there was only a mild degree of chronic inflammation with few eosinophils.	18485037
Fibrosis Assessment, Bronchiolitis, Interstitial inflammation, Pneumonia	Altered Intercellular Communication	The commonality of our cases was a combination of bronchiolitis and interstitial inflammation and fibrosis but little or no intra-alveolar organizing pneumonia.	18486892
Inflammation, Intracranial Aneurysm	Altered Intercellular Communication	There is evidence suggesting that inflammation plays an important role in the pathogenesis of intracranial aneurysms (IAs).	18487018
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Systemic inflammation after inspiratory loading in chronic obstructive pulmonary disease.	18488438
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Patients with chronic obstructive pulmonary disease (COPD) present systemic inflammation.	18488438
ARCN1 gene, Inflammation	Altered Intercellular Communication	We hypothesized that the increased respiratory load that characterizes COPD can contribute to systemic inflammation in these patients.	18488438
ARCN1 gene, Inflammation	Altered Intercellular Communication	This study confirms the presence of systemic inflammation in COPD, shows that maximal inspiratory loading does not increase the levels of pro-inflammatory cytokines (IL-1beta, IL-8) in COPD patients or controls, but suggests that the former may be unable to mount an appropriate systemic anti-inflammatory response to exercise.	18488438
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Inflammation has repeatedly been demonstrated to be associated with the metabolic syndrome (MetS) and insulin resistance, but the relative importance of different aspects of the inflammatory process is largely unexplored.	18489581
Inflammation, Edema, Megacolon, Toxic	Altered Intercellular Communication	Abdominal computed tomography demonstrated severe colonic dilation, inflammation and oedema consistent with toxic megacolon.	18489880
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Inflammation plays a critical role in acute myocardial infarction.	18489929
Inflammation, Diverticulitis, Perforation (observation)	Altered Intercellular Communication	Most are asymptomatic; however, they are vulnerable to inflammation with subsequent consequences including diverticulitis and perforation.	18491085
Infarction, Inflammation	Altered Intercellular Communication	Admission glucose, infarction size CK(MAX), and inflammation (CRP) were not significantly related to OGTT results.	18491170
Inflammation, acute diverticulitis	Altered Intercellular Communication	However, patients with a recent history of acute diverticulitis have a significant attenuation in SERT expression and function, likely secondary to previous inflammation.	18491196
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is essential in the development of atherosclerosis and markers of inflammation, in particular C-reactive protein, predict the cardiovascular risk.	18491455
Uremia, Cardiovascular Diseases	Altered Intercellular Communication	These results suggest that the Vitamin D Receptor alleles b, a, T could be considered novel risk factors in the pathogenesis of inflammation-related, atherosclerosis-dependent cardiovascular disease risk in uremic patients.	18491455
Vaginitis	Altered Intercellular Communication	However, it was previously unknown that the apoptotic neutrophils brought about by T. vaginalis can influence vaginal inflammation.	18492033
Inflammation, Disorder of tendon	Altered Intercellular Communication	A new review suggested that an inflammatory process may be related to the development of tendinopathy and that the inflammation may also play a role in chronic tendinopathy.	18492052
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	Differential expression of multiple genes associated with inflammation, cellular adhesion, and metastasis was observed.	18492237
Inflammatory Bowel Diseases, Sarcoidosis, Spinal Fractures	Altered Intercellular Communication	Our findings imply that QUS measurements of the calcaneus in patients with an inflammatory condition, such as sarcoidosis and IBD, are likely of limited value to identify patients with a vertebral fracture.	18492278
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Previous studies have suggested that low-grade systemic inflammation is involved in the pathogenesis of type 2 diabetes mellitus.	18493107
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	However, limited information is available about the relationship of diabetes mellitus and inflammation in Asia.	18493107
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide (eNO) is a useful marker of eosinophilic airway inflammation in asthmatics.	18493167
Inflammation, Destruction (action)	Altered Intercellular Communication	In conclusion, the results of the study indicate that pregnant diabetics demonstrate a higher degree of periodontal inflammation and destruction compared to non-pregnant diabetics and healthy non-pregnant patients.	18494196
Cerebral Amyloid Angiopathy, Inflammation	Altered Intercellular Communication	Cerebral amyloid angiopathy (CAA) can rarely be complicated by vascular and perivascular inflammation.	18494780
Sporothrix, Staphylococcus lugdunensis, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Skin and lymph node biopsy showed tuberculoid granulomatous inflammation and Grocott-methamine silver-positive yeast forms consistent with Sporothrix and Staphylococcus lugdunensis was identified from tissue culture.	18494815
Granulomatous inflammation	Altered Intercellular Communication	After 15 months, two punch biopsies showed scarring and granulomatous inflammation; cultures and histochemical stains were negative for microorganisms.	18494815
Inflammation	Altered Intercellular Communication	The iris and ciliary body showed nongranulomatous chronic inflammation predominantly made up of plasma cells, Russell bodies, and plasmacytoid lymphocytes.	18495247
Inflammation	Altered Intercellular Communication	Circulating C-reactive protein (CRP) is a marker of inflammation and is associated with the incidence of cardiovascular events.	18495270
Inflammation, Anemia	Altered Intercellular Communication	Anemia of inflammation in patients with acute or chronic acute-phase activation is a common clinical problem.	18495462
Inflammation, Hypoxia, hepcidin	Altered Intercellular Communication	Main inducers of hepcidin are iron overload, hypoxia and inflammation, where the latter has been linked to hepcidin via increased interleukin-6 (IL-6).	18495462
Sepsis, Inflammation	Altered Intercellular Communication	These results suggest that the response to antithrombin III supplementation may be affected by both a systemic inflammation and impaired synthesis in patients with sepsis.	18496242
Inflammation	Altered Intercellular Communication	Skin biopsies showed histological evidence of elastophagocytosis with scant lymphocytic inflammation.	18496436
Pleurisy, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Pleural inflammation is a common feature of SLE; however, as an initial presentation in SLE is rare.	18496695
Inflammation	Altered Intercellular Communication	The inflammation process in psoriatic skin is characterized by influx of leukocytes, hyperproliferation and aberrant differentiation of keratinocytes regulated via cytokines.	18496701
Communicable Diseases, Occluded, Inflammation, Blood Coagulation Disorders	Altered Intercellular Communication	ICA occlusion caused by spread of infection in the deep neck space may cause accelerated coagulopathy due to ICA wall inflammation.	18497495
Inflammation, Neoplasms	Altered Intercellular Communication	All methods are limited because peritumoral inflammation cannot be precisely distinguished from infiltration by the tumor.	18497511
Communicable Diseases, Specimen Type - Fistula, Inflammation, Traumatic injury	Altered Intercellular Communication	Underlying conditions were iatrogenic trauma from prior pulmonary surgery (4 patients), significant anastomotic leaks after an esophagogastrectomy (4 patients), delayed presentation (> 24 hours) of a perforated esophagus (4 patients), leak after esophageal surgery (3 patients), and esophagobronchial fistula secondary to inflammation and infection (2 patients).	18498803
Inflammation, Diabetic Angiopathies	Altered Intercellular Communication	Advanced glycation end products (AGEs) have been found to play a role in inflammation and vascular complications.	18498890
Inflammation, Arterial Injury, Polycystic Ovary Syndrome	Altered Intercellular Communication	Low-grade chronic inflammation is not accompanied by structural arterial injury in polycystic ovary syndrome.	18499295
Inflammation, Carotid Intima-Media Thickness, Atherosclerosis, Prostate Cancer Outcomes Study, Polycystic Ovary Syndrome	Altered Intercellular Communication	To evaluate the presence of premature subclinical atherosclerosis, measured by examining carotid intima-media thickness (IMT) and to investigate whether the IMT may be linked to low-grade chronic inflammation, assessed by C-reactive protein (CRP), in young women with polycystic ovary syndrome (PCOS).	18499295
Inflammation, Atherosclerosis, Prostate Cancer Outcomes Study, Arterial Injury, Hyperandrogenism	Altered Intercellular Communication	This study suggests that PCOS itself is not associated with structural arterial injury, carotid IMT is not linked to low-grade chronic inflammation and hyperandrogenism may be associated with subclinical atherosclerosis and cardiovascular risk in young women with PCOS.	18499295
Inflammation	Altered Intercellular Communication	Pus cultures collected after incision were negative, leaving origin of the inflammation undetermined.	18500001
Inflammation	Altered Intercellular Communication	Histological examination of the mass revealed an active chronic inflammation caused by a foreign body.	18500018
Inflammation, Hypopyon	Altered Intercellular Communication	Slit-lamp examination revealed inflammation of the flap interface, a partially detached flap, anterior chamber reaction, and hypopyon.	18500093
Intestinal metaplasia, Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Histologically, no difference was observed in the frequency of active inflammation, Helicobacter pylori infection or intestinal metaplasia.	18500262
Inflammation, Metabolic Syndrome X, Atherosclerosis	Altered Intercellular Communication	Systemic and vascular markers of inflammation in relation to metabolic syndrome and insulin resistance in adults with elevated atherosclerosis risk.	18501910
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Systemic and vascular markers of inflammation showed significant associations with IR and the MetS and may be incorporated into traditional CVD risk prediction models.	18501910
Depression, CTCAE, Bipolar Disorder	Altered Intercellular Communication	The incidence or recurrence of major depression is greatly increased in women during the transition to and after menopause and hormonal changes occurring during these periods are thought to play an important role in depressive recurrence.	18502089
vascular inflammations	Altered Intercellular Communication	C-reactive protein and interleukin-6 were also measured to look at vascular inflammation.	18502267
Inflammation, Atherosclerosis	Altered Intercellular Communication	Oxidative stress and inflammation are involved in the pathophysiology of atherosclerosis.	18502300
Inflammation	Altered Intercellular Communication	Oxidative stress and inflammation are implicated in the pathogenesis of many age-related diseases.	18502748
Inflammation	Altered Intercellular Communication	Stress-induced overproduction of inflammatory cytokines, such as interleukin-8 (IL-8), is one of the early events of inflammation.	18502748
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a prominent role in the development of atherosclerosis, which is the most important risk factor for vascular events.	18504081
Single organ dysfunction, Inflammation	Altered Intercellular Communication	The clinical course, as indicated by markers of inflammation, average and maximum organ failure score, ICU stay and ICU and 90-day mortality, was the same.	18504551
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Low paraoxonase-I activity in type 2 diabetes mellitus may contribute to increased cardiovascular risk via an effect on enhanced systemic low-grade inflammation.	18505467
Presenile dementia, Lewy Bodies, "Alzheimers Disease	Altered Intercellular Communication	Dementia with Lewy Body and Alzheimer's disease exhibit degeneration of the cholinergic neurons, and currently, the primary target of treatment is the cholinergic neurotransmitter system.	18506194
Inflammation, Temporomandibular Joint	Altered Intercellular Communication	Effect of estrogen on bone resorption and inflammation in the temporomandibular joint cellular elements.	18506373
palladium, Memory impairment	Altered Intercellular Communication	These findings demonstrate that emotional memory deficits observed in PD may result from dopaminergic treatment and suggest an involvement of dopaminergic neurotransmission in emotional processing.	18506391
Inflammation, Appendicitis, CTCAE, Chronic appendicitis	Altered Intercellular Communication	Findings were categorised as showing acute appendicitis, acute recurrent appendicitis, subacute recurrent appendicitis, chronic appendicitis, or appendices without inflammation.	18506922
Inflammation	Altered Intercellular Communication	CT imaging showing either fat stranding with remarkable fluid content or abscess indicates the presence of severe inflammation and is related to adverse surgical outcomes.	18507091
Inflammation, Disease	Altered Intercellular Communication	Patients who seek medical advice late or have signs of severe inflammation or extraluminal appendicolith on their CT imaging are associated with more severe diseases and are prone to develop complications of surgery at this time and should be better treated conservatively.	18507091
Inflammation, Neoplasms	Altered Intercellular Communication	We measured the signal intensity in a series of DWI images and calculated the apparent diffusion coefficient (ADC) values to differentiate the tumors from normal tissue, inflammation, or another lesion.	18507125
Bronchiectasis, Bronchial Infection, CTCAE	Altered Intercellular Communication	Bronchiectasis is defined as a permanent dilation of the airways arising from chronic bronchial inflammation/infection.	18507830
Inflammation, Array, Hamartoma, Calcinosis, Hypertrophy	Altered Intercellular Communication	Microscopically, all hamartomas were involved by myocyte hypertrophy and disarray, without inflammation or calcification.	18508110
Lysosomal Storage Diseases, Inflammation, Mucopolysaccharidoses	Altered Intercellular Communication	In mucopolysaccharidosis type IIIB, a lysosomal storage disease causing early onset mental retardation in children, the production of abnormal oligosaccharidic fragments of heparan sulfate is associated with severe neuropathology and chronic brain inflammation.	18509511
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Inflammation may still contribute to neurodegeneration in late stages of the disease, albeit independent of TLR4/MyD88.	18509511
Inflammation, Neoplasms	Altered Intercellular Communication	In nasal/maxillary areas, FDG-avid tumours were consistently more localised than on CT, suggesting that soft tissue masses on CT were partly due to inflammation.	18509641
Cholecystitis, Bile duct structure	Altered Intercellular Communication	In the past, acute cholecystitis was a contraindication to laparoscopic cholecystectomy because of the greater risk of injury to the biliary duct, but acute gallbladder inflammation was a contraindication to open cholecystectomy, too.	18510025
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Dynamics of pro-inflammatory and anti-inflammatory cytokine release during acute inflammation in chronic obstructive pulmonary disease: an ex vivo study.	18510721
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	We report on a reliable ex vitro model for the investigation of acute lung inflammation and its resolution using lung parenchymal explants from COPD patients.	18510721
Inflammation, destruction joint	Altered Intercellular Communication	Resistin was associated with increased inflammation, particularly by the acute-phase reactant IL-1Ra antagonizing IL-1beta, joint destruction, glucocorticosteroids and with reduced BMD and TLM.	18511473
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	In addition to lung inflammation, it is now accepted that increased alveolar cell apoptosis is also part of emphysema pathophysiology.	18511705
Arteritis	Altered Intercellular Communication	The purpose of this study was to establish the value of contrast-enhanced MRI, proven to be sensitive to extradural arteritis, for the identification of intracranial vessel wall inflammation.	18511868
Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Endothelial dysfunction, Chronic Kidney Diseases	Altered Intercellular Communication	High incidence of cardiovascular disease (CVD) in chronic kidney disease (CKD) patients is a result of an interlaced relation between oxidative stress, endothelial dysfunction (ED) and inflammation.	18511874
Inflammation, Primary malignant neoplasm, Rheumatoid Arthritis, Coronary Artery Disease, Chronic disease	Altered Intercellular Communication	Significant advances have been made in understanding the relation between dietary factors and inflammation, which is a central component of many chronic diseases, including coronary artery disease, rheumatoid arthritis, cancer prevention.	18511896
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	To investigate the relationship between lymphoid neogenesis in the synovium of patients with rheumatoid arthritis (RA) and characteristics of inflammation and disease severity.	18512774
Refractory anemias, Inflammation	Altered Intercellular Communication	These findings indicate that synovial lymphoid neogenesis is associated with more severe synovial and systemic inflammation, but this is not confined to a specific clinical subset of RA.	18512774
Refractory anemias, Inflammation	Altered Intercellular Communication	The presence of tissue destruction within the nodule despite the absence of IL-17A suggests that IL-17A may be an important amplifier rather than an absolute requirement for inflammation in RA.	18512780
Airway structure, Asthma	Altered Intercellular Communication	Evaluation of airway inflammation is important for the diagnosis and treatment of asthma.	18513240
Airway structure, Inflammation, Asthma	Altered Intercellular Communication	Exhaled breath condensate (EBC) is a minimally invasive method for assessing inflammation and may be useful for monitoring airway inflammation in asthma.	18513240
Airway structure, Asthma	Altered Intercellular Communication	Measurement of EBC biomarkers is a non-invasive and useful way to evaluate airway inflammation in patients with asthma.	18513240
Acute Lung Injury, Inflammation, Acidosis	Altered Intercellular Communication	In EBC from a small cohort of patients with ALI, inhaled salbutamol significantly decreased airspace acidosis, a marker of inflammation, and was associated with a trend toward decreased markers of nitrosative and oxidative stress.	18513388
Inflammation, Congestive heart failure	Altered Intercellular Communication	High baseline IGFBP-1 level was a significant predictor of CHF, independent of established CHF risk factors and inflammation markers.	18513511
Inflammation, Hemorrhage, Pain Distress Question, Perforation (observation), Ear Inflammation, Glomus tympanicum	Altered Intercellular Communication	Complications were lesion of auricular canal, perforation of tympanic membrane, local inflammation, bleeding, pain and otitis.	18513905
Inflammation, Idiopathic Pulmonary Fibrosis, Nonspecific interstitial pneumonia	Altered Intercellular Communication	Our results suggest that lung fibroblasts tend to induce a Th1-type immune response under normal conditions, and that a Th2-type immune response does not play a significant role in smoldering inflammation around the established lesions in IPF and NSIP.	18514095
Inflammation, Hippocampal atrophy, Memory impairment	Altered Intercellular Communication	Converging animal findings suggest that higher peripheral levels of inflammation are associated with activation of central inflammatory mechanisms that result in hippocampal neurodegeneration and related impairment of memory function.	18514163
Inflammation, Impaired cognition	Altered Intercellular Communication	To our knowledge, this is the first report of a relationship between a peripheral marker of IL-6 and hippocampal grey matter volume, raising the possibility that low-grade systemic inflammation could plausibly presage subclinical cognitive decline in part via structural neural pathways.	18514163
Depressive disorder, Inflammation	Altered Intercellular Communication	Association of major depressive disorder with serum myeloperoxidase and other markers of inflammation: a twin study.	18514165
Minimal Disseminated Disease, Depressive disorder, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Major depressive disorder (MDD) has been linked to inflammation, but this association may be due to common precursors to both depression and inflammation.	18514165
Minimal Disseminated Disease, Inflammation	Altered Intercellular Communication	We sought to examine whether MPO and other markers of inflammation are associated with MDD and whether the association is confounded by genetic or other shared familial factors.	18514165
Minimal Disseminated Disease, Inflammation	Altered Intercellular Communication	However, the association between inflammation and MDD is largely due to common genetic liability.	18514165
Minimal Disseminated Disease, Inflammation	Altered Intercellular Communication	Our results are consistent with the hypothesis that genes promoting inflammation are involved in the pathogenesis of MDD.	18514165
Arteriolosclerosis, Inflammation, Fibrosis Assessment, MPV17 gene	Altered Intercellular Communication	Arteriolosclerosis, glomerulosclerosis, cortical fibrosis, and chronic inflammation by using CD68 density were measured morphometrically.	18514988
Inflammation, Uremic pruritus, Viral hepatitis, type G	Altered Intercellular Communication	Association of uraemic pruritus with inflammation and hepatitis infection in haemodialysis patients.	18515654
Inflammation, Uremic pruritus, Communicable Diseases, HD Term Type, Hepatitis C	Altered Intercellular Communication	Chronic inflammation and hepatitis C virus (HCV) infection have been implicated in the pathogenesis of uraemic pruritus in haemodialysis (HD) patients.	18515654
HD Term Type, Pruritus, Inflammation, Uremic pruritus	Altered Intercellular Communication	Our study demonstrated the heavy burden of pruritus in HD patients and corroborated the role of inflammation in the pathogenesis of uraemic pruritus.	18515654
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Recent studies implicated inflammation playing an important role in the occurrence and advancement of colorectal cancer.	18516001
Inflammation, Colorectal Carcinoma, Adenoma of large intestine	Altered Intercellular Communication	Colorectal adenoma as the representative precursor lesion of colorectal cancer has meaningful association with inflammation.	18516001
Pancreatitis, Acute, Inflammation, Obstruction of colon, Necrosis	Altered Intercellular Communication	It is known that colonic obstruction in acute pancreatitis is more likely found in splenic flexure and transverse colon caused by severe inflammation of body and tail of pancreas leading to pressure necrosis.	18516005
Inflammation	Altered Intercellular Communication	Clinical and pathological findings showed non-specific inflammation in the pelvis and ovary.	18516926
Inflammation, Hematoma, Hypocalcemia, Paralysed	Altered Intercellular Communication	Complications excluding transient hypocalcemia (one-side paralysis, subcutaneous haematoma and inflammation) were present in < 1 % of patients.	18517135
Inflammation, Hydrocephalus, Meningitis	Altered Intercellular Communication	Symptomatic local inflammation, aseptic meningitis, and hydrocephalus are reported in a group of patients treated with second generation/modified platinum coils.	18518706
Inflammation	Altered Intercellular Communication	Shorter leukocyte telomeres and increased gammaH2AX in colonocytes might reflect oxidative damage secondary to inflammation.	18519043
Primary malignant neoplasm	Altered Intercellular Communication	Alterations of gap junctional intercellular communication appear to play a role in the development and progression of cancer.	18519234
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Little is known about the phenotype of these cells, despite accumulating evidence suggesting a potential role for chronic inflammation in the etiology of prostate cancer.	18519750
Aneurysm, Inflammation	Altered Intercellular Communication	A gastric artery aneurysm complicated by a dissection of gastric and hepatic arteries: possible role of adventitial inflammation and disruption of internal elastic lamina in splanchnic artery dissection.	18520493
Aneurysm, Inflammation	Altered Intercellular Communication	Little is currently known about aneurysms or dissections of splanchnic arteries; however, observation of adventitial inflammation and internal elastic lamina may help disclose the etiology and pathogenesis.	18520493
Bacterial Vaginosis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	To evaluate interrelationships between bacterial vaginosis (BV), vaginal yeast, vaginal practices (cleansing and drying/tightening), mucosal inflammation, and HIV acquisition.	18520679
Hepatitis	Altered Intercellular Communication	In alcoholics, exposure of Kupffer cells to intestinal-borne Gram-negative bacteria increases free radical release, which may, in turn, enhance cytokine secretion, creating a positive feedback loop, which contributes to liver inflammation.	18521549
Inflammation	Altered Intercellular Communication	Computerized tomography of the abdomen and pelvis displayed signs of acute inflammation of the distal colon and rectum.	18521689
Inflammation, Neoplasms	Altered Intercellular Communication	[Cystatins: cysteine proteases regulation and disturbances in tumors and inflammation].	18522223
Inflammation, Takayasu Arteritis, Pulmonary artery structure, Arteritis	Altered Intercellular Communication	We diagnosed the patient as having Takayasu's arteritis based on chronic inflammation and the morphologic features of pulmonary artery lesion.	18522795
Heart Diseases	Altered Intercellular Communication	No patient had structural heart diseases or inflammatory conditions.	18523031
Disease	Altered Intercellular Communication	Following primary exclusion of a tumor disease, a lymph node biopsy demonstrated a typical picture of a granulomatous inflammation-Whipple's lymphadenitis with partial exemption of the Gram reaction, and stain features corresponding to T. whipplei, which is regarded as the etiological agent causing this disorder.	18523887
Ischemia, Inflammation	Altered Intercellular Communication	The lower labial frenum attached to the free gingival margin can promote local tension, resulting in tissue ischemia, promoting the development of gingival recession, as well as complicating oral hygiene, resulting in a local biofilm accumulation and chronic inflammation.	18524265
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Leukotrienes are inflammatory mediators, and inflammation has been implicated in the pathogenesis of Alzheimer disease.	18525291
Pathogenesis of HIV Opportunistic Infection, Communicable Diseases, BRCA1 wt Allele, Granulomatous inflammation	Altered Intercellular Communication	An overwhelming immune reaction resulting in granulomatous inflammation after infection with opportunistic pathogens is termed immune reconstitution inflammatory syndrome (IRIS).	18528698
Polyp of small intestine, Inflammation, Granulomatous	Altered Intercellular Communication	Upper endoscopy revealed a continuous inflammation with pseudopolyps of the small bowel and histologically, a granulomatous infiltrate was detected.	18528698
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	It is well known that the fibrinolytic system is of importance in inflammation, wound healing, and fibrosis development.	18533186
Inflammation, deficiency aspects, Anemia	Altered Intercellular Communication	Chronic inflammation and mild Fe deficiency could account for the association between unexplained anaemia and elevated Cu levels.	18533287
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The human anti-IL-1 beta monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis.	18534016
Inflammation, Fever, CTCAE	Altered Intercellular Communication	IL-1beta is a proinflammatory cytokine driving joint inflammation as well as systemic signs of inflammation, such as fever and acute phase protein production.	18534016
Cartilage destruction, Inflammation	Altered Intercellular Communication	The mouse IL-1 receptor cross-reacts with human IL-1beta, and it was demonstrated that ACZ885 can completely suppress IL-1beta-mediated joint inflammation and cartilage destruction in mice.	18534016
Inflammation	Altered Intercellular Communication	Fatty liver and chronic inflammation in Chinese adults.	18534708
Inflammation, Blood Clot	Altered Intercellular Communication	Microscopically, neither microorganisms nor inflammation were found in the thrombi and/or valve tissues.	18534771
Weight decreased, Myositis	Altered Intercellular Communication	In conclusion, exercise but not weight loss had a beneficial effect on markers of muscle inflammation and anabolism in frail obese elderly individuals.	18535122
Renal Osteodystrophy, Anemia	Altered Intercellular Communication	Additional risk factors associated with short-term mortality besides malnutrition-inflammation complex syndrome were anemia and renal osteodystrophy.	18535370
Acute inflammation, Conjunctival scar	Altered Intercellular Communication	Additional advantages observed included faster wound healing, diminished conjunctival scarring, improved patient comfort, and decreased postoperative inflammation.	18535586
Cauda Equina, Orbital Pseudotumor	Altered Intercellular Communication	This is the first case of selective cauda equina hypertrophy with idiopathic inflammation.	18537137
Granulomatous inflammation	Altered Intercellular Communication	INF-gamma production by Tc1 cells causes granulomatous inflammation.	18537857
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	However, some reports indicate that cystatin C may be influenced not only by GFR, but also by malignancy, inflammation and high doses of corticosteroids.	18538095
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation, complement factor h, and age-related macular degeneration: the Multi-ethnic Study of Atherosclerosis.	18538409
vascular inflammations	Altered Intercellular Communication	In turn, low levels of soluble RAGE (sRAGE) have recently emerged as a valuable biomarker of vascular inflammation.	18538667
Inflammation, GCD Regimen, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Histologically, the GCD is characterized by a spectrum of histopathological features in a wide range of tissue specimens, often demonstrating features of active chronic inflammation, with or without non-caseating granuloma formation.	18538712
Inflammation	Altered Intercellular Communication	The presence of numerous pigmented macrophages in association with such an inflammation should raise suspicion of the diagnosis.	18538712
Mood Disorders	Altered Intercellular Communication	Alterations of GABAergic neurotransmission are assumed to play a crucial role in the pathophysiology of mood disorders.	18538859
Inflammation, Muscular Atrophy	Altered Intercellular Communication	Muscle atrophy, inflammation and clinical outcome in incident and prevalent dialysis patients.	18538898
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Female sex, presence of cardiovascular disease, inflammation and low insulin-like growth factor-1 levels were associated with increased significant odd ratios of MA in each cohort.	18538898
Cessation of life, Inflammation, Diabetes Mellitus, Cardiovascular Diseases	Altered Intercellular Communication	After adjustment for age, sex, inflammation, diabetes, cardiovascular disease, glomerular filtration rate and/or time on hemodialysis, the hazard ratio of death for moderate/severe MA was 2.62 (95% CI: 1.34, 5.13; p=0.001) and 3.04 (95% CI: 1.61, 5.71; p=0.0001) in the incident and prevalent cohorts respectively.	18538898
Inflammation	Altered Intercellular Communication	Increased MA is more common in female dialysis patients and associated with inflammation, poor nutritional and anthropometric status, as well as a 3-fold increased 4-6 year mortality.	18538898
Inflammation	Altered Intercellular Communication	The histology of colonic biopsies shows inflammation of the mucosa, and either thickening of the subepithelial collagen band or an increase of lymphocytes in the surface epithelium.	18538968
Hemorrhage, Laryngitis	Altered Intercellular Communication	It is well known that phonotraumatic events may produce laryngeal inflammation, vocal fold hemorrhage and different types of mass lesions.	18538985
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Involvement of the choroid plexus in multiple sclerosis autoimmune inflammation: a neuropathological study.	18539342
Viral Encephalitis	Altered Intercellular Communication	Intense CP inflammation is observed in viral encephalitis.	18539342
Intraocular inflammation, Lens Opacities	Altered Intercellular Communication	Ophthalmic evaluations included analysis of the degree of intraocular inflammation and assessment of lens opacity by the Lens Opacities Classification System (LOCS) III.	18539933
Inflammation	Altered Intercellular Communication	Seroreactivity against alphaA-, alphaB-, or betaB1-, but not betaB2-crystallin was related to active anterior segment inflammation.	18539933
Inflammation, Uveitis	Altered Intercellular Communication	The relationship between the presence of specific anti-crystallin antibodies and active inflammation may indicate a role for these autoantibodies in uveitis pathogenesis.	18539933
Inflammation, Congenital neurologic anomalies, Dyslipidemias, Coronary Arteriosclerosis, Renal Insufficiency, Hypertension, CTCAE	Altered Intercellular Communication	In the general population, RVO is associated with hypertension, dyslipidemia, and renal dysfunction, but not with atherosclerotic disease, systemic inflammation, and hematologic abnormalities.	18539932
HD Term Type, Hemochromatosis, Inflammation, septic	Altered Intercellular Communication	Ferritin and FIC values were correlated with iron storage and inflammation markers and the results of HD patients compared to those of septic and hemochromatosis patients.	18541151
HD Term Type, Hemochromatosis, Inflammation, septic	Altered Intercellular Communication	1) In the whole HD population, high ferritin levels were associated to low FIC values; 2) the correlation of ferritin with iron indices and inflammation markers in HD patients was intermediate in between that of septic and hemochromatosis patients; 3) the FIC level of HD patients was lower than that of the other two groups.	18541151
HD Term Type, Inflammation	Altered Intercellular Communication	The high ferritin levels of HD patients are not synonymous with either inflammation or of high levels of iron storage.	18541151
Inflammation, Wounds and Injuries, Autoimmune Diseases, malignant disease, Virus Diseases, Inflammatory disorder	Altered Intercellular Communication	The level of neopterin in serum is increased in patients suffering from viral infections, autoimmune diseases, systemic inflammation, allograft rejection and malignant diseases, while that of C-reactive protein (CRP) is known to rise during inflammatory diseases and traumas.	18541395
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Consequences of low plasma histidine in chronic kidney disease patients: associations with inflammation, oxidative stress, and mortality.	18541578
Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Plasma histidine concentrations were significantly lower in CKD patients with history of cardiovascular disease, presence of plaques, protein-energy wasting, and inflammation.	18541578
Albumins, Inflammation, Cardiovascular Diseases, Diabetes Mellitus	Altered Intercellular Communication	After adjustment for age, sex, cardiovascular disease, inflammation, diabetes mellitus, serum S-albumin, and amino acid supplementation, the association between low histidine and mortality remained significant (hazard ratio: 1.55; 95% CI: 1.02, 2.40; P < 0.05).	18541578
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Low plasma concentrations of histidine are associated with protein-energy wasting, inflammation, oxidative stress, and greater mortality in CKD patients.	18541578
Inflammation, Edema	Altered Intercellular Communication	An electrophysiological study performed at 4 weeks revealed abnormalities suggestive of edema or inflammation and an absence of signs of denervation.	18543507
Inflammation, Neurotoxicity Syndromes	Altered Intercellular Communication	Nitric oxide (NO) is an important messenger intra and extra molecular implicated in vasodilatation, contractility, neurotransmission, neurotoxicity and inflammation.	18543682
Inflammation, Neurotoxicity Syndromes	Altered Intercellular Communication	Nitric oxide (NO) is an important messenger intra and extra molecular implicated in vasodilatation, contractility, neurotransmission, neurotoxicity and inflammation.	18543682
Inflammation	Altered Intercellular Communication	The infiltrate was characterized by numerous epithelioid histiocytes admixed with acute and chronic inflammation.	18544059
Inflammation	Altered Intercellular Communication	In the cyst wall peripheral nerves, arteries, veins, and chronic inflammation were present.	18545048
Inflammation, Osteopenia	Altered Intercellular Communication	Common causes for implant removal were bone loss and/or inflammation (52.5%), and implant mobility (43.4%).	18545052
Inflammation, Cryptitis	Altered Intercellular Communication	Cryptitis and glandular inflammation were observed in the colon, ileum, and stomach, whereas villous blunting was present in the ileal and duodenal mucosa.	18545145
Communicable Diseases, Inflammation	Altered Intercellular Communication	It can be reliably used in the setting of radiation, infection, and inflammation.	18545214
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	The inflammation and emphysema was around the anus, bilateral inguinal region, and right flank.	18546868
Exanthema, Conjunctivitis	Altered Intercellular Communication	We report a case of a 42-year old lady with recurrent bilateral nodular conjunctival inflammation following a diffuse papulo-vesicular rash, mainly over her trunk and scalp.	18546922
Mastitis, Suppurative inflammation	Altered Intercellular Communication	The first two patients predominantly showed the characteristics of a purulent inflammation, and on mammogram the third patient appeared to have mastitis carcinomatosa.	18547028
Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Histopathological investigation revealed a lobular, non-caseating granulomatous inflammation.	18547028
Inflammation, Psoriasis, Obesity	Altered Intercellular Communication	Obesity in psoriasis: leptin and resistin as mediators of cutaneous inflammation.	18547319
Airway structure, Asthma	Altered Intercellular Communication	The exhaled nitric oxide (FeNO) is a non-invasive marker of airway inflammation in asthma.	18547853
Inflammation, Carcinogenesis, Chronic sinusitis, Carcinoma of lung	Altered Intercellular Communication	Chronic rhinosinusitis may be a marker of pan-airway inflammation and its association with lung cancer risk provides evidence linking inflammation to lung carcinogenesis, especially among women.	18548585
Carcinoma of lung	Altered Intercellular Communication	Epidemiologic evidence suggests that chronic inflammatory conditions of the lung may increase lung cancer risk.	18548585
Inflammation, Kidney Diseases	Altered Intercellular Communication	Polymorphonuclear leukocyte priming and low grade inflammation are related to severity of kidney disease.	18548979
Inflammation	Altered Intercellular Communication	The ANCA inflammation had affected the middle sized and small vessels of especially the upper and lower airways, and the kidneys.	18549177
Inflammation, Granulomatosis with polyangiitis	Altered Intercellular Communication	Tissue studies showed granulomatous inflammation of the airways which is typical of Wegener's disease.	18549177
Inflammation, Systemic Vasculitis	Altered Intercellular Communication	This type of inflammation is absent in microscopic polyangiitis.	18549177
Inflammation, atherosclerotic	Altered Intercellular Communication	Variations in candidate genes participating in oxidative stress, inflammation, and their interactions are potentially associated with diseases of atherosclerotic origin.	18549840
Inflammation, Thrombosis, Rupture, Atherosclerosis, Endothelial dysfunction	Altered Intercellular Communication	Our understanding of atherosclerosis has shifted from a focal disease whose hallmark is symptoms caused by a severe stenosis to a systemic disease characterized by endothelial dysfunction (ED) and plaque inflammation, with the potential for rupture and thrombosis mainly in those with subcritical stenosis.	18549869
Inflammation, Dental Plaque	Altered Intercellular Communication	These interventions are now understood to decrease plaque inflammation and thereby promote plaque stability.	18549869
Inflammation	Altered Intercellular Communication	Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) appears to be a specific marker of plaque inflammation that may play a direct role in the formation of rupture-prone plaque.	18549869
vascular inflammations, Coronary Arteriosclerosis	Altered Intercellular Communication	Lp-PLA(2) may provide additional clinically relevant information that shows which patients have a high level of atherosclerotic disease activity as manifested by vascular inflammation, ED, and increased risk for progression toward rupture-prone plaque.	18549869
Inflammation, Heart	Altered Intercellular Communication	Authorities in the field suggest that inflammation predicts short-range (up to 17 months) coronary death.	18549934
Inflammation, Hemorrhage, Irritation - emotion, Urination, Nephrolithiasis	Altered Intercellular Communication	Problem in urine discharge, burning sensation and painful urination, inflammation and bleeding in the kidney, irritable condition of bladder, haemorrhage of kidney and removal of blocked urine and kidney stone were the frequently reported disorders in the study area.	18550306
Inflammation, Nephrogenic rest, Fibrosis Assessment, Atherosclerosis	Altered Intercellular Communication	Chronic inflammation and accelerated atherosclerosis as important cofactors in nephrogenic systemic fibrosis following intravenous gadolinium exposure.	18551245
Inflammation, Atherosclerosis	Altered Intercellular Communication	Prior studies indirectly suggested a possible impact of chronic inflammation and accelerated atherosclerosis--a common feature in kidney diseased patients--whereas recent data focused almost exclusively on gadolinium (Gd)-based MR contrast agents.	18551245
Inflammation	Altered Intercellular Communication	Therefore, we present the first case with an extraordinary long time course in terms of chronic inflammation.	18551245
Inflammation, Atherosclerosis	Altered Intercellular Communication	Certain other cofactors such as chronic inflammation and accelerated atherosclerosis seem to be involved.	18551245
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Fever was present and the levels of inflammation markers were markedly elevated.	18552068
Inflammation	Altered Intercellular Communication	Biopsy of the cavity wall showed chronic inflammation, fungal hyphae, and rare spherule-like structures.	18552586
alpha-Thalassemia, Seizures, Epilepsy, Generalized	Altered Intercellular Communication	The haptoglobin HP2-2 genotype has been associated with idiopathic generalized epilepsies and altered iron metabolism in children with alpha-thalassaemia can potentially interfere with neurotransmission and increase the risk of seizures.	18554871
Gingivitis, Dental Plaque	Altered Intercellular Communication	Scores of dental bacterial plaque and gingival inflammation increased during CT and the oral microbial composition changed towards a more acidophilic flora.	18554960
Inflammation, Thrombosis, Pathology, Occluded, Malignant Neoplasms, Phlebitis	Altered Intercellular Communication	The aim of the present review was to discuss the normal anatomy and the pathologies of the inferior mesenteric vein, including partial or total thrombosis secondary to inflammation (pyophlebitis) and malignancy, occlusion, dilatation and reversed flow, which are rarely encountered.	18555041
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterised by airflow limitation, and has many components including mucus hypersecretion, oxidative stress, and airway inflammation.	18555912
Presenile dementia	Altered Intercellular Communication	C4BP levels in cerebrospinal fluid (CSF) of dementia patients and controls were low compared to levels in plasma and correlated with CSF levels of other inflammation-related factors.	18556068
Inflammation	Altered Intercellular Communication	The underlying cause for the chronic systemic inflammation remains unknown.	18556380
Communicable Diseases, Inflammation, Peritonitis	Altered Intercellular Communication	We studied serum procalcitonin (PCT), which has been reported as an accurate marker for infection and inflammation, with respect to being a diagnostic and prognostic indicator of persistent chronic inflammation after peritonitis in patients with PD-related peritonitis.	18556380
palladium, Inflammation, Peritonitis	Altered Intercellular Communication	PD patients after peritonitis may be associated with prolonged systemic inflammation.	18556380
Inflammation, hepcidin, Anemia	Altered Intercellular Communication	Hepcidin is linked to anemia and inflammation in peritoneal dialysis patients.	18556388
Fibrosis Assessment, Nephritis	Altered Intercellular Communication	Furthermore, localization of STAT3 activation to individual cell types suggests that this pathway may play a pivotal role in promoting renal inflammation and fibrosis.	18556750
Inflammation, Swelling, Ocular Motility Disorders	Altered Intercellular Communication	Intravitreal triamcinolone acetonide is effective in treating various ocular disorders associated with inflammation and swelling of the retina.	18556948
Human papilloma virus infection, Bowenoid papulosis, Chronic inflammation, Vulval intraepithelial neoplasia	Altered Intercellular Communication	Two different forms of vulvar intraepithelial neoplasia (VIN) are recognised: (1) usual-type (bowenoid) VIN, which is related to high-risk papillomavirus infection, and (2) differentiated (simplex) VIN, which is associated with chronic inflammation.	18559375
Communicable Diseases, Inflammation, BDI - Functional Impairment	Altered Intercellular Communication	Persistent infection, inflammation, and functional impairment in older Latinos.	18559636
Communicable Diseases, Inflammation	Altered Intercellular Communication	Further research examining the influence of infection, immune response, and inflammation on longitudinal trajectories of physical functioning is warranted.	18559636
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	Association of insulin resistance and inflammation with peripheral arterial disease: the National Health and Nutrition Examination Survey, 1999 to 2004.	18559705
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	Although the role of inflammation in the pathophysiology of peripheral arterial disease (PAD) is well established, the contribution of insulin resistance (IR) to PAD is less clear.	18559705
Inflammation	Altered Intercellular Communication	These data establish a role of IR in PAD and highlight the relative importance of inflammation in patients with and without IR.	18559705
Familial Mediterranean Fever	Altered Intercellular Communication	This is at least partially attributed to the ability of FMF to simulate a variety of inflammatory conditions afflicting the follicular unit.	18559762
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Cerebral inflammation as well as systemic immunological alterations has been reported in Alzheimer's disease (AD).	18560127
Immune-mediated	Altered Intercellular Communication	The IL23/IL23R pathway may modulate STAT3 transcriptional activity which is an essential regulator not only of immune-mediated inflammation, but also of inflammatory-associated apoptosis resistance.	18560602
Inflammation, SMALL PATELLA SYNDROME	Altered Intercellular Communication	Typical MR patterns of signal alterations suspected of inflammation of CPPS patients were able to be detected as T 2w hypointense triangular, stringy (n = 12, 66.6 %) contrast-enhancing signal alterations without a nodular shape with well circumscribed margins of the capsula and without pericapsular signal alterations.	18561065
Inflammation, Primary malignant neoplasm, Prostate carcinoma	Altered Intercellular Communication	The spectroscopic analysis of the signal alterations suspected of inflammation showed normal Cholin+Creatin/Citrate SI ratio values in 3 patients (SI < 0.5), ratios suspected of low grade cancer in 3 patients (SI 0.5 and < 0.7) and ratios suspected of intermediate grade prostate cancer in 3 patients (SI > 0.7 and < 3.0).	18561065
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Malignant Neoplasms, Atherosclerosis	Altered Intercellular Communication	Systemic inflammation may play an important role in the development of atherosclerosis, type 2 diabetes, and some cancers.	18562168
Inflammation, heart overload, Chronic Kidney Diseases	Altered Intercellular Communication	We explored the prognostic value of biomarkers of cardiac overload [B-type natriuretic peptide (BNP) and N-terminal pro-B-type natriuretic peptide (NT-proBNP)] and inflammation [high-sensitivity C-reactive protein (hsCRP)] for all-cause mortality in patients with CKD.	18562472
Communicable Diseases, Weight decreased, Pneumonitis	Altered Intercellular Communication	hMPV infection protected mice against subsequent viral challenge, as demonstrated by undetectable viral titers, lack of body weight loss, and a significant reduction in the level of lung inflammation.	18562525
Hyperammonemia, Hepatic Encephalopathy	Altered Intercellular Communication	It has been recently proposed that inflammation-associated alterations and hyperammonemia may cooperate in the induction of hepatic encephalopathy.	18562979
Hyperammonemia, Inflammation	Altered Intercellular Communication	The aim of the present work was to assess whether there is a correlation between the alterations in parameters reflecting inflammation, hyperammonemia, and the presence of MHE.	18562979
Barrett Esophagus, Esophagitis	Altered Intercellular Communication	Repeat EGD for Barrett's screening should not be performed out of concern for a missed diagnosis except when BE may have been obscured by overlying esophageal inflammation.	18564120
Symptoms, Airway structure	Altered Intercellular Communication	Here, we studied IFN-lambda mRNA expression in the airways of stable asthmatics in comparison with healthy subjects and in relation to asthma symptoms, non-invasive parameters of airway inflammation and lung function parameters.	18564328
Inflammation	Altered Intercellular Communication	Histopathological examination of the resected specimen reaffirmed the nonspecific inflammation.	18564669
Gingivitis	Altered Intercellular Communication	Though the oral hygiene index was generally good, some of the children had mild gingival inflammation and periodontal pocketing.	18564728
Inflammation, Neoplasms	Altered Intercellular Communication	Polymorphonuclear neutrophils are potent effector cells of inflammation that are an important component of tumour development and progression.	18565119
Inflammation	Altered Intercellular Communication	Additionally, adiponectin and resistin may play a role in inflammation and immune responses.	18565135
ACSM3 gene, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Kidney Diseases	Altered Intercellular Communication	Serum concentrations of S-adenosylmethionine (SAM), SAH and total homocysteine (tHcy) were determined by HPLC in 124 CKD stage 5 patients (GFR range 1-11 m/min) and 47 control subjects, and related to renal function, presence of CVD, inflammation and protein-energy wasting (PEW).	18565329
ACSM3 gene, Inflammation	Altered Intercellular Communication	While SAH was not associated with the presence of inflammation or PEW, it was a significant contributor (OR; 4.9 (CI 1.8-12.8), P<0.001) to CVD in a multinomial logistic regression model (pseudo r(2)=0.31).	18565329
ACSM3 gene, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Concentrations of serum SAH and SAM in CKD stage 5 patients are associated with renal function, but not with inflammation or PEW.	18565329
Sepsis, Inflammation, Septic Shock	Altered Intercellular Communication	PCT results were classed as: 0.5 ng/mL=sepsis unlikely; > or =0.5 to <2=sepsis possible; > or =2 to <10=systemic inflammation; > or =10=septic shock.	18565757
Acute Lung Injury, Inflammation, Vascular System Injuries	Altered Intercellular Communication	Microvascular injury, inflammation, and coagulation play critical roles in the pathogenesis of acute lung injury (ALI).	18565951
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	C-reactive protein: a predictive factor and marker of inflammation in inflammatory bowel disease.	18566104
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Markers of generalized inflammation of the acute-phase response are associated with recurrent stroke, rather than IL-6, C-reactive protein, or fibrinogen in particular.	18566306
Airway structure, Lung Injury	Altered Intercellular Communication	Exposure of the lung epithelium to reactive oxygen species without adequate antioxidant defenses leads to airway inflammation, and may contribute to lung injury.	18566333
methyldopa, Inflammation	Altered Intercellular Communication	The results of recent studies have implicated local inflammation and complement activation as the processes involved in the pathogenesis of age-related macular degeneration (AMD).	18566438
Inflammation	Altered Intercellular Communication	These results suggest that Abeta activates the complement system within drusen by blocking the function of factor I leading to a low-grade, chronic inflammation in subretinal tissues.	18566438
methyldopa, Inflammation, Drusen	Altered Intercellular Communication	These findings link four factors that have been suggested to be associated with AMD: inflammation, complement activation, Abeta deposition, and drusen.	18566438
Granuloma, Sarcoidosis, Inflammation	Altered Intercellular Communication	Because granulomas form when cellular immunity fails to clear antigenic stimuli, attenuated mDC function in sarcoidosis may contribute to susceptibility and persistence of the chronic inflammation characteristic of this disease.	18566441
Inflammation	Altered Intercellular Communication	We demonstrate that synovial lymphoid neogenesis is a reversible process associated with inflammation which is neither restricted to nor preferentially associated with autoantibody positive rheumatic conditions.	18566445
Airway structure, Inflammation	Altered Intercellular Communication	It has been shown that complement-C3-deficient mice have reduced inflammation of asthmatic airways.	18566738
allergic inflammation	Altered Intercellular Communication	Our results suggest that LD block 4 confers susceptibility to adult BA with mechanisms relevant to the effector phase of allergic inflammation.	18566738
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cerebrovascular accident	Altered Intercellular Communication	These gene differences were consistent with reported differences after stroke in areas such as injury and inflammation markers, the myosin heavy chain profile, and high prevalence of impaired glucose tolerance and type 2 diabetes.	18566945
Inflammation, Pancreatitis, Mass of pancreas	Altered Intercellular Communication	Focal pancreatitis (FP) is a confined inflammation that mimics a pancreatic mass.	18568532
Congenital Structural Myopathy, Uveitis	Altered Intercellular Communication	Because calsequestrin is located in the cell membranes of the eye muscle cell during the myotubular stage of the cell cycle, its targeting might be the primary reaction which leads to extraocular muscle inflammation in patients with GH.	18568642
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Granulocyte-colony stimulating factor (G-CSF) is used for the mobilization of bone marrow and endothelial progenitor cells, though G-CSF-induced inflammation may cause endothelial dysfunction.	18569019
Inflammation, Primary malignant neoplasm, Necrosis	Altered Intercellular Communication	Extracellular HMGB1, either actively secreted or passively released by necrotic cells, is linked to inflammation and cancer.	18569640
Inflammatory abnormality of the eye	Altered Intercellular Communication	Seven patients achieved remission of their ocular inflammation.	18569794
Intraocular inflammation	Altered Intercellular Communication	Especially in patients with an intraocular inflammation this diagnosis may lead to severe differential diagnostic problems.	18569799
Acute inflammation	Altered Intercellular Communication	To describe an unusual case of latent syphilis that presented with postoperative inflammation.	18569802
Cataract, Acute inflammation	Altered Intercellular Communication	A 62-year-old African American woman developed persistent postoperative inflammation following cataract surgery.	18569802
Communicable Diseases, Inflammation	Altered Intercellular Communication	She was referred to Infectious Disease and the inflammation resolved with intravenous penicillin.	18569802
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histologic examination revealed nonspecific chronic inflammation and fibrosis in all cases and foci of squamous epithelium in one case.	18569817
Lacrimal gland structure, Orbital Pseudotumor	Altered Intercellular Communication	Initially, a presumptive diagnosis of lacrimal gland lymphoma or an idiopathic inflammation was made.	18569819
Inflammation	Altered Intercellular Communication	The impact of chronic inflammation on bone turnover in hemodialysis patients.	18569918
Inflammation	Altered Intercellular Communication	Studies in other pathological entities have shown an impact of chronic inflammation on bone metabolism.	18569918
HD Term Type, Inflammation	Altered Intercellular Communication	In the present study, the impact of chronic inflammation on bone turnover in HD patients was evaluated.	18569918
HD Term Type, Inflammation	Altered Intercellular Communication	Chronic inflammation has a negative impact on bone turnover in HD patients.	18569918
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Intensification of oxidative stress and inflammation in type 2 diabetes despite antihyperglycemic treatment.	18570678
Inflammation	Altered Intercellular Communication	We have previously shown that DM type 2 patients are exposed to increased OS and inflammation contributed in part by primed peripheral polymorphonuclear leukocytes (PMNLs).	18570678
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	To characterize the effect of oral medication on PMNL priming, on PMNL-related and on systemic inflammation, in correlation to changed diabetes parameters in patient with newly diagnosed type 2 DM.	18570678
Inflammation, Demographics Domain	Altered Intercellular Communication	Systemic inflammation markers (fibrinogen, CRP), higher in DM, decreased following both treatments.	18570678
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	To test the hypothesis that early knee and hand osteoarthritis (OA) development is characterized by detectable changes in serum proteins relevant to inflammation, cell growth, activation, and metabolism several years before OA becomes radiographically evident.	18571442
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Changes in serum proteins implicated in matrix degradation, cell activation, inflammation and bone collagen degradation products accompany early OA development and can precede radiographic detection by several years.	18571442
Inflammation, Respiratory Tract Infections	Altered Intercellular Communication	Ghrelin treatment suppresses neutrophil-dominant inflammation in airways of patients with chronic respiratory infection.	18571961
Inflammation, Respiratory Tract Infections	Altered Intercellular Communication	The present study investigated whether or not ghrelin can reduce neutrophil-dominant inflammation in airways of patients with chronic respiratory infection.	18571961
Airway structure, Respiratory Tract Infections, Cachexia	Altered Intercellular Communication	Synthesized ghrelin was administered intravenously for 3 weeks to 7 cachectic patients with chronic respiratory infection to confirm ghrelin's effects on airway inflammation and nutrition state.	18571961
Airway structure	Altered Intercellular Communication	Neutrophils, neutrophil products and inflammatory cytokines in sputum were used as markers of airway inflammation.	18571961
Airway structure	Altered Intercellular Communication	Ghrelin administration suppressed airway inflammation by decreasing neutrophil accumulation in lungs and increased body weight.	18571961
Inflammation, Acute Coronary Syndrome, Nonstress test	Altered Intercellular Communication	Inflammation plays a pivotal role in the pathophysiology of non-ST elevation acute coronary syndromes (NSTEACS).	18572029
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Increased 18F-fluorodeoxyglucose uptake in abdominal aortic aneurysms in positron emission/computed tomography is associated with inflammation, aortic wall instability, and acute symptoms.	18572354
Inflammation, Aneurysm	Altered Intercellular Communication	Maximum aortic FDG uptake correlated significantly with inflammation, followed by increased MMP expression and histopathologic characteristics of aneurysm wall instability and clinical symptoms.	18572354
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Wide variation in thrombin generation in patients with atrial fibrillation and therapeutic International Normalized Ratio is not due to inflammation.	18573110
Inflammation, Bronchiolitis Obliterans, alloimmunity	Altered Intercellular Communication	Here, we hypothesized that PGD-induced inflammation augments alloimmunity, thereby predisposing to broncholitis obliterans syndrome.	18573422
Inflammation, alloimmunity	Altered Intercellular Communication	Increased donor HLA-II expression along with PGD-induced allograft inflammation promotes the development of donor specific alloimmunity.	18573422
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	These data suggest that inflammation may partly mediate the familial influences on hypertension risk.	18574071
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	The interaction among inflammation, Hemostasis, and fibrinolysis plays a major role in the genesis of coronary artery disease (CAD).	18574391
Nasal inflammation	Altered Intercellular Communication	Initial CPAP therapy might be responsible for evoking local nasal inflammation.	18575017
Inflammatory abnormality of the eye	Altered Intercellular Communication	In view of severe intra-ocular inflammation, the anterior chamber was punctured.	18575052
Inflammation, Pain Distress Question, Ulcer	Altered Intercellular Communication	A significant improvement was obtained in the SUC-LIS 95-treated patient group with regard to local tissue inflammation as well as pain and burning, and consequently, in ulcer size and the evolution of granulation tissue.	18575771
Dermatitis, Atopic	Altered Intercellular Communication	Atopic dermatitis is a chronic, inflammatory condition affecting up to 20% of children.	18577032
Inflammation, Carcinogenesis, Hyperplasia, Prostate carcinoma	Altered Intercellular Communication	PGE2 and LTB4 are involved in inflammation and carcinogenesis in several tissues but have not been studied in prostate cancer and hyperplasia until now.	18577464
Inflammation, Carcinogenesis, Benign prostatic hypertrophy	Altered Intercellular Communication	PGE2 and inflammation may be associated to stromal benign prostatic hyperplasia whereas LTB4 may play a role in prostate carcinogenesis.	18577464
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Small dense low-density lipoprotein (LDL) has emerged as an important risk factor in coronary atherosclerosis and vascular inflammation, which is related to neointimal hyperplasia.	18577812
Inflammation, Periodontitis	Altered Intercellular Communication	Analysis of the received morphological data let make more exact the mechanism of forming and persisting the inflammation focus round dental root apex and give practical recommendations how to treat chronic apical periodontitis.	18577916
Inflammation, Neurologic Deficits, Demyelination, Disturbance	Altered Intercellular Communication	It has been shown that in the presence of the vascular risk factors the neurological deficit can increase in this group of patients not only due to inflammation and demyelinization but to vascular disturbances as well.	18577954
Inflammatory abnormality of the eye	Altered Intercellular Communication	These data suggest that the time to control of ocular inflammation is faster with mycophenolate than with methotrexate.	18579209
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Atrial inflammation and fibrosis status before surgery, but not the changes of connexins during surgery, were associated with the occurrence of post-CABG AF.	18580064
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	There were no signs of regional inflammation or malignancy.	18580235
Inflammation	Altered Intercellular Communication	In addition, we report 3 cases of ocular adnexal extranodal marginal zone B-cell lymphoma that show sclerosing inflammation in the background and numerous IgG4+ monotypic plasma cells.	18580683
Inflammation	Altered Intercellular Communication	To reduce the intracranial pressure, internal decompressive craniotomy was performed, which consisted of a right temporal lobectomy that allowed us to remove the focal necrotic-hemorrhagic tissue, decrease inflammation, and avoid subsequent chronic gliotic scarring.	18580790
Traumatic, Brain Injuries, Hypopituitarism	Altered Intercellular Communication	Chronic hypopituitarism warranting hormone replacement occurs in approximately 20% of patients after complicated mild, moderate, or severe traumatic brain injury and is associated with more severe brain injuries and increased disability.	18580806
Traumatic, Tyrosine Transaminase Deficiency Disease	Altered Intercellular Communication	We sought to define the incidence, risk factors, and neurobehavioral consequences of chronic hormonal deficiencies after complicated mild, moderate, or severe traumatic brain injury.	18580806
Inflammation, Diabetes Mellitus, Insulin-Dependent	Altered Intercellular Communication	Gingival inflammation was 69.7% in the group of 5-9 year-old, and 83.7% in the group of 10-14 year-old with type 1 diabetes mellitus.	18581583
Inflammation	Altered Intercellular Communication	By contrast, the reduction in hemoglobin concentration associated with P. falciparum infection accompanied by inflammation was larger and strongly depended on genotype (normal, -21.8 g/L; heterozygous, -16.7 g/L; and homozygous, -4.6 g/L).	18582194
Inflammation	Altered Intercellular Communication	alpha(+)-Thalassemia limits the decline in hemoglobin concentration that is associated with afebrile infections, particularly those that are accompanied by inflammation.	18582194
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Cell signaling via Toll-like receptors (TLRs) leads to synovial inflammation in rheumatoid arthritis (RA).	18584044
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Baker's cysts are a common ultrasonographic finding in knees with chronic osteoarthritic pain and are associated with synovial inflammation and its grade.	18584176
Disease susceptibility, Nerve Degeneration	Altered Intercellular Communication	This ChAc patient showed faint immunoreactivity in the caudate nucleus and globus pallidus with antibodies against the striatal neurotransmitters, methionine-enkephalin, leucine-enkephalin and substance P. The difference in patterns of neuronal vulnerability could reflect those in the mechanisms of neurodegeneration between ChAc and HD.	18584183
Inflammation, Comorbidity	Altered Intercellular Communication	The risk associated with the iron storage protein ferritin was significantly elevated, but this association could reflect disease-related inflammation or comorbidity.	18584481
Inflammation, Sleep Apnea, Obstructive, Autonomic nervous system disorders, Cardiovascular Diseases	Altered Intercellular Communication	Obstructive sleep apnea syndrome (OSAS) is associated with the pathogenesis of cardiovascular disease, and inflammation and autonomic dysfunction.	18584894
Inflammation, Sleep Apnea, Obstructive, Autonomic nervous system disorders, Cardiovascular Diseases	Altered Intercellular Communication	Markers of inflammation and autonomic dysfunction are increased in patients with OSAS, and nCPAP might help to reduce these risk factors for cardiovascular diseases.	18584894
Delirium, Psychotic Disorders, Psychotic symptom	Altered Intercellular Communication	Our results suggest that psychotic symptoms in delirious patients may be related to increased dopamine neurotransmission, as reflected by increased CSF HVA concentration, providing direct evidence to support the dopaminergic theory of psychosis.	18585537
Asthma, Upper Respiratory Infections	Altered Intercellular Communication	Nebulized budesonide (Pulmicort Respules, AstraZeneca, Wilmington, DE) provides control of respiratory tract inflammation in asthmatic patients.	18585575
Inflammation, Anemia	Altered Intercellular Communication	Inflammation and iron deficiency are two important causes of anemia.	18586459
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	5-methyltetrahydrofolate administration is associated with prolonged survival and reduced inflammation in ESRD patients.	18587236
Inflammation, Mirizzi Syndrome, Specimen Type - Fistula	Altered Intercellular Communication	We previously suggested that the natural history of Mirizzi syndrome may not end with just a cholecystobiliary fistula and that the continuous inflammation in the triangle of Calot area may result in a complex fistula involving the biliary tract and the adjacent viscera.	18587614
Acute inflammation, Standing position, Amnesia, TBX1 wt Allele	Altered Intercellular Communication	This is the first report of TGA associated with postoperative inflammation in which amnesia was provoked by orthostatic positioning.	18589346
Refractory anemias, Rheumatoid Arthritis, Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	To ascertain prevalence and prognostic implication of painless myocardial ischemia (PMI) in patients with rheumatoid arthritis (RA) in respect to stage, severity of inflammation and characteristics of the lipid profile.	18590108
Refractory anemias, Inflammation	Altered Intercellular Communication	RA patients with PMI had changes in the lipid profile in the direction of elevation of atherogenic components and C-reactive protein characterizing severity of inflammation.	18590108
Refractory anemias, Inflammation, atherosclerotic, Coronary heart disease	Altered Intercellular Communication	About 50% RA patients free of clinical symptoms of coronary heart disease had PMI caused by both coronarogenic (atherosclerotic) factors and non-coronarogenic (immunocomplex inflammation) mechanisms.	18590108
Inflammation, Dental Plaque	Altered Intercellular Communication	Plaque accumulation and marginal inflammation did not differ between teeth and implants.	18590257
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	[Peripheral vascular disease: prevalence, mortality and relationship with inflammation in hemodialysis].	18590498
Peripheral Vascular Diseases, Inflammation, Sepsis	Altered Intercellular Communication	Peripheral vascular disease (PVD) is a common disease among patients undergoing hemodialysis leading to increase morbidity and mortality with a high risk of inflammation and sepsis.	18590498
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	There is an association between PVD and inflammation.	18590498
Inflammation, Dental Plaque	Altered Intercellular Communication	Neopterin and CD3+CD4+CD28- lymphocytes are associated with CAD extent in stable patients, thereby emphasizing the inherent role of inflammation in atherogenesis itself beyond plaque destabilization.	18590932
Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Diabetes Mellitus	Altered Intercellular Communication	A relationship between inflammation, measured by C-reactive protein (CRP), and forced vital capacity (FVC) in diabetes or metabolic syndrome (MetS) has not been established.	18591402
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Polymorphism homozygosity in exon-1 region was significantly related to lower serum MBL levels (p < 0.001), to liver inflammation (p = 0.034, OR = 11.7) and, in a lesser degree, to fibrosis.	18592362
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Polymorphisms in promoter sites -221nt and -550nt were not shown to be related with serum MBL levels or progress to liver inflammation and fibrosis.	18592362
Fibrosis Assessment, Hepatitis C, Hepatitis	Altered Intercellular Communication	These findings suggest that polymorphisms in MBL2 gene exon-1 region are related to low serum MBL levels and progression of HCV infection to liver inflammation and fibrosis.	18592362
Inflammation, anatomical bulb	Altered Intercellular Communication	Clinical evaluation revealed inflammation of the eyelid and an irregular and erythematous superior bulbar conjunctiva with disruption of the limbal architecture.	18592447
Granulomatous inflammation, Granulomatosis with polyangiitis, Vasculitis, CTCAE	Altered Intercellular Communication	The diagnosis of an early systemic Wegener's granulomatosis was based on elevated proteinase 3-titres and cutaneous histologic findings as necrotising vasculitis and granulomatous inflammation.	18592451
Hematoma, Malignant Neoplasms	Altered Intercellular Communication	Differential diagnosis of a testicular mass includes inflammatory conditions, malignant tumors and traumatic lesions, including hematomas and hematocele.	18592776
Inflammation, Actinomycosis	Altered Intercellular Communication	In all cases, histopathologic staining of the specimens revealed chronic inflammation containing actinomycosis abscesses confirmed with microbiologic identification.	18592800
Asthma	Altered Intercellular Communication	Therefore, extra-fine hydrofluoroalkane-beclomethasone may be particularly useful for treating peripheral airway inflammation in asthma.	18592826
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	[Systemic inflammation in COPD and asthma: similarities and differences].	18592988
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	While recent studies have shown that patients with COPD and patients with asthma exhibit evidence of airway and systemic inflammation, markers of systemic inflammation have not been compared between the two diseases.	18592988
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	Although COPD and asthma share common markers of systemic inflammation, serum levels of TGF-beta1 and alpha1-AT may reflect differences between the diseases.	18592988
Inflammation, Hypertension, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	In conclusion, aging, central fat, hypertension and diabetes, inflammation process, low social status and abstinence from a Mediterranean diet seem to predict CVD events within a 5-year period.	18593800
Inflammation	Altered Intercellular Communication	Chronic inflammation and oxidative stress are common features in hemodialysis patients.	18594136
Inflammation, Diverticulitis, Diverticulum, Diverticulosis	Altered Intercellular Communication	Diverticulosis was defined as three or more diverticula present and diverticulitis as diverticulosis with inflammation.	18594842
Tissue damage, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Neutrophil granulocytes infiltrate the intestinal mucosa in active ulcerative colitis (UC), and may contribute to tissue damage and inflammation.	18594843
Inflammation, Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Serological proteomics of gastritis: degradation of apolipoprotein A-I and alpha1-antitrypsin is a common response to inflammation irrespective of Helicobacter pylori infection.	18594986
Communicable Diseases, Gastritis	Altered Intercellular Communication	We conclude that the degradation or metabolization of acute-phase proteins, apolipoprotein A-I, and alpha1-antitrypsin, is a common response to gastric inflammation irrespective of Hp infection.	18594986
Refractory anemias, Inflammation, Chief complaint (finding)	Altered Intercellular Communication	Complains and morphological features of inflammation in the larynx were considerably more frequent in patients with active RA.	18595486
Inflammation, MS gene	Altered Intercellular Communication	Cerebrospinal fluid B cells correlate with early brain inflammation in multiple sclerosis.	18596942
Inflammation	Altered Intercellular Communication	Our data support an important role of CSF B cells in acute brain inflammation in CIS and RRMS.	18596942
Inflammation, Carcinogenesis	Altered Intercellular Communication	These findings suggest that consuming broccoli interacts with GSTM1 genotype to result in complex changes to signalling pathways associated with inflammation and carcinogenesis in the prostate.	18596959
Cerebrovascular Disorders, Inflammation, Thrombophilia, Disease	Altered Intercellular Communication	Sleep deprivation may worsen systemic inflammation and hypercoagulable states, which are known to be involved in the pathogenesis of diseases such as cerebrovascular or cardiovascular disease.	18597046
Inflammation, Crohn Disease	Altered Intercellular Communication	Chronic inflammation, impaired intestinal adsorption, and bowel resection may have an impact on lipid metabolism before and after intestinal surgery for Crohn's disease (CD).	18597099
Inflammation, Rheumatoid Arthritis, Polyarthritis	Altered Intercellular Communication	Biomarkers of inflammation in patients with unclassified polyarthritis and early rheumatoid arthritis.	18597410
Inflammation, Atherosclerosis, Cardiovascular Diseases, Rheumatoid Arthritis, Low-Density Lipoproteins	Altered Intercellular Communication	Relations between autoantibodies against oxidized low-density lipoprotein, inflammation, subclinical atherosclerosis, and cardiovascular disease in rheumatoid arthritis.	18597411
Inflammation, Atherosclerosis, Refractory anemias, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	We investigated relations between oxLDL-ab, inflammation, subclinical atherosclerosis, and cardiovascular disease (CVD) in patients with RA.	18597411
Inflammation	Altered Intercellular Communication	An indication for interaction was found (p = 0.09), suggesting that inflammation modifies the relation between HDL cholesterol and oxLDL-ab.	18597411
Refractory anemias, Inflammation, Atherosclerosis	Altered Intercellular Communication	OxLDL-ab were strongly related with the degree of inflammation and may predispose to a higher risk for CVD, as they were independently associated with subclinical atherosclerosis in patients with RA.	18597411
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Mucosal inflammation in IBD can be detected through fecal biomarkers, though the present enzyme-linked immunoabsorbent assay (ELISA) tests require laboratory facilities.	18597588
Colitis	Altered Intercellular Communication	The calprotectin and lactoferrin rapid tests are as good as the ELISA tests in detecting colonic inflammation.	18597588
Inflammation, Periodontitis	Altered Intercellular Communication	Gingival crevicular fluid alkaline phosphatase activity reflects periodontal healing/recurrent inflammation phases in chronic periodontitis patients.	18597602
Inflammation	Altered Intercellular Communication	One of these host enzymes is alkaline phosphatase (ALP), the GCF activity of which has been associated with periodontal inflammation.	18597602
Inflammation, Periodontitis	Altered Intercellular Communication	Therefore, GCF ALP reflects the short-term periodontal healing/recurrent inflammation phases in chronic periodontitis patients.	18597602
Inflammation, Periodontal Route of Administration	Altered Intercellular Communication	A 12-year-old girl was referred to the Department of Pediatric Dentistry, Hotel-Dieu/Garanciere Hospital, for acute gingival inflammation and periodontal destruction.	18597610
Inflammation, Actual blood loss	Altered Intercellular Communication	The oxygenator Avecor offers similar results in terms of inflammation and coagulation profiles and blood loss during valvular surgery compared to a standard uncoated control oxygenator.	18598318
Attention deficit hyperactivity disorder	Altered Intercellular Communication	The involved genetic polymorphisms have been shown to modulate evoked GBRs, which therefore could be a possible marker of impaired neurotransmission in ADHD.	18598680
Heart failure	Altered Intercellular Communication	Inflammation-sensitive plasma proteins are associated with increased incidence of heart failure: a population-based cohort study.	18599061
Inflammation, Heart failure, Cardiovascular Diseases	Altered Intercellular Communication	Although inflammation has been associated with different cardiovascular diseases, the relationships with future heart failure (HF) are unclear.	18599061
Inflammation, leukemia, Ulcer, Agranulocytosis lab result, Syphilis	Altered Intercellular Communication	Agranulocytosis after the use of metamizole is part from leukaemia and lues, a rare reason for non-healing ulcers of the mucosa of the oral cavity without fulminant signs for inflammation.	18600360
Inflammation, Tophus, Hyperuricemia	Altered Intercellular Communication	Ultrasonography allows detection of tophi and inflammation in a third and in a fourth, respectively, of asymptomatic hyperuricemic patients.	18600510
Seizures, Childhood Ganglioglioma, Autistic Disorder, Inflammation	Altered Intercellular Communication	Resection (ganglioglioma with excessive inflammation) resulted in seizure freedom and marked reduction of the autistic features.	18602026
ARCN1 gene, Peripheral Vascular Diseases, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) and peripheral arterial disease (PAD) are both inflammatory conditions.	18602520
Inflammation, Bone necrosis	Altered Intercellular Communication	Patients were checked for exposed bone, osteonecrosis, mucosal defects, inflammation, and oral hygiene.	18602738
Multiple Organ Failure, Inflammation	Altered Intercellular Communication	Development of multiple organ failure may be related to impaired microcirculatory perfusion as a result of systemic inflammation.	18603065
Inflammation, Atherosclerosis	Altered Intercellular Communication	In conclusion, higher serum UA and low-grade inflammation are closely linked to alterations in lipoprotein metabolism which may represent an early sign of atherosclerosis in asymptomatic subjects.	18603253
Liver carcinoma, Hepatic inflammation, FAM126A gene	Altered Intercellular Communication	The risk of hepatocellular carcinoma (HCC) increases with the severity of hepatic inflammation.	18603357
Tumor necrosis, Neoplasms	Altered Intercellular Communication	Interleukin (IL)-1beta and tumor necrosis factor (TNF)-alpha are proinflammatory cytokines with multiple biological effects and may play essential roles in inflammation-linked tumor development.	18603357
Sarcoma, Hodgkin Disease	Altered Intercellular Communication	It is a distinctive lesion with features simulating inflammatory conditions, Hodgkin's disease and various sarcomas.	18603905
Inflammation, Hemorrhage, Intestinal Obstruction	Altered Intercellular Communication	It is usually asymptomatic but approximately 4% are symptomatic with complications such as bleeding, intestinal obstruction, and inflammation.	18604139
Splenic Infarction, Inflammation, thromboembolic	Altered Intercellular Communication	Splenic infarction is a common cause of left upper quadrant pain and must be suspected in patients with hematologic or thromboembolic conditions and signs of localized or systemic inflammation.	18604554
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Inflammation plays an important role in coronary artery disease (CAD).	18604638
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Chronic inflammation is the common feature of inflammatory bowel disease.	18605194
Crohn Disease, Inflammation	Altered Intercellular Communication	determination of sE-selectin in children with Crohn's disease is of significance in estimation of inflammation activity.	18605194
Refractory anemias, Rheumatoid Arthritis, Inflammation, physiopathological	Altered Intercellular Communication	Rheumatoid arthritis (RA) is accompanied by long lasting inflammation, which may lead to arterial dysfunction and premature aging of the arteries.	18605247
Inflammation, Fibrosis Assessment, Dystrophic calcification, Necrosis	Altered Intercellular Communication	The major histopathologic changes were in skeletal muscle, which were focal necrosis and inflammation, followed by fibrosis and dystrophic calcification.	18606777
Inflammation, Albuminuria, Chronic Kidney Diseases	Altered Intercellular Communication	Paricalcitol reduces albuminuria and inflammation in chronic kidney disease: a randomized double-blind pilot trial.	18606901
Inflammation, Diabetic Nephropathy, Microalbuminuria, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Endothelial dysfunction and inflammation predict development of diabetic nephropathy in the Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria (IRMA 2) study.	18609080
Inflammation, Endothelial dysfunction, Unexpected Adverse Event	Altered Intercellular Communication	In a Cox enter model with combined Z-scores for biomarkers of endothelial dysfunction (vWf, sVCAM-1, sICAM-1, sE-selectin) and for biomarkers of inflammation (hs-CRP, IL-6, fibrinogen), endothelial dysfunction (hazard ratio for a 28 % increase ( = 1 SD) in Z-score) 3.20 (1.56 to 6.56), p = 0.001) and UAER (HR for a 75 % increase ( = 1 SD) in UAER) 2.61 (1.30 to 5.23), p = 0.007) were found as independent predictors.	18609080
Inflammation, Diabetic Nephropathy, Microalbuminuria, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Endothelial dysfunction and possibly inflammation are novel predictors of progression to diabetic nephropathy in patients with type 2 diabetes and microalbuminuria independently of traditional risk factors.	18609080
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Smoking also seems to modify inflammation in H. pylori infection.	18609143
Gastritis, Peptic Ulcer	Altered Intercellular Communication	We analysed the effect of smoking on gastric inflammation, humoral response to H. pylori and peptic ulcer disease among 318 Finnish H. pylori-positive patients (age 18-75 years; 73 smokers).	18609143
Atrophic	Altered Intercellular Communication	In the gastric body, smokers showed milder chronic and neutrophilic inflammation and less atrophy (4% versus 17%, p=0.004).	18609143
Inflammation, Gastritis, Smoking, Atrophic	Altered Intercellular Communication	In H. pylori-positive gastritis, smoking reduced inflammation and atrophy in the gastric body as well as humoral response to H. pylori.	18609143
Chronic Infantile Neurological, Cutaneous, and Articular Syndrome, Inflammation, Hereditary Autoinflammatory Diseases, Urticaria, Arthropathy, Fever	Altered Intercellular Communication	Chronic infantile neurological cutaneous and articular (CINCA) syndrome is an autoinflammatory disease, defined by the triad of urticarial rash, neurological manifestations, and arthropathy, accompanied by recurrent fevers and systemic inflammation.	18609262
Inflammation, Chronic insufficiency	Altered Intercellular Communication	Chronic insufficiency alters homeostasis, in part due to endothelial inflammation.	18609532
Inflammation, Sarcoidosis	Altered Intercellular Communication	Analysis of induced sputum has been used as a non-invasive tool for investigating the airways and may reflect the endobronchial and parenchymal inflammation in patients with sarcoidosis.	18610674
Inflammation	Altered Intercellular Communication	In conclusion, both high salt and COX-2 overexpression promote chemical-induced gastric carcinogenesis, possibly related to chronic inflammation, induction of PGE(2), disruption of cell kinetics and induction of inflammatory cytokines.	18611916
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	Putative role of endothelial lipase in dialysis patients with hypoalbuminemia and inflammation.	18612200
Inflammation, Malnutrition, Cardiovascular Diseases	Altered Intercellular Communication	A recent study suggests that inflammation and malnutrition are strongly associated with cardiovascular disease in dialysis patients.	18612200
Inflammation, LIPG gene, Hypoalbuminemia	Altered Intercellular Communication	To clarify the role of EL in dialysis patients, we evaluated serum markers on the basis of the presence of hypoalbuminemia and inflammation.	18612200
Inflammation, LIPG gene, Hypoalbuminemia	Altered Intercellular Communication	Our findings suggest that the link between EL, hypoalbuminemia and inflammation may play an important role in atherogenesis in dialysis patients.	18612200
Inflammation	Altered Intercellular Communication	Mild chronic anterior chamber inflammation was observed intermittently throughout the follow-up period.	18612232
Inflammation, Fibrous	Altered Intercellular Communication	Conversely, the degree of inflammation was markedly lower in the study group: low-grade fibrous plaques occurred in 45.7% of cross-sections in the study group, versus 11.3% in the control group (P=0.006).	18612439
Inflammation	Altered Intercellular Communication	We further suggest that reduction of plaque inflammation is an important aspect of this stabilization.	18612439
Inflammation	Altered Intercellular Communication	The activity and inflammation scores in Nrf2 -686/-684 A/G carriers were significantly lower than those in the non-A/G carriers (p = 0.038 and p = 0.019, respectively).	18613447
Carcinogenesis, Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The -686/-684 haplotype of Nrf2 gene may be associated with the development of gastric inflammation and with gastric carcinogenesis without the influence of H. pylori infection, although overall association with gastric carcinogenesis seems to be none.	18613447
Inflammation, Prostate Cancer Outcomes Study	Altered Intercellular Communication	These findings add to the growing body of evidence linking inflammation to cardiorespiratory fitness in PCOS women.	18616717
deficiency aspects, vascular inflammations, Allostasis, Amenorrhea	Altered Intercellular Communication	Altered resting vascular resistance in premenopausal oestrogen deficient physically active amenorrheic women is not associated with vascular inflammation or oxidative stress, but rather with parameters that reflect metabolic allostasis and dietary intake, suggesting a potential role for chronic energy deficiency in vascular regulation.	18616718
Cessation of life, Inflammation	Altered Intercellular Communication	Polymorphonuclear neutrophil granulocytes have a central role in innate immunity and their programmed cell death and removal are critical for efficient resolution of acute inflammation.	18617697
Inflammation	Altered Intercellular Communication	In a mouse model of self-resolving inflammation, MPO also prolonged the duration of carrageenan-induced acute lung injury, as evidenced by enhanced alveolar permeability and accumulation of neutrophils parallel with suppression of neutrophil apoptosis.	18617697
Inflammation	Altered Intercellular Communication	Our results indicate that MPO functions as a survival signal for neutrophils and thereby contribute to prolongation of inflammation.	18617697
Malignant neoplasm of skin, Inflammation, Traumatic injury	Altered Intercellular Communication	Trauma, scars and/or chronic inflammation have been reported as underlying causes of skin cancers in occasional cases.	18617744
Inflammation, Corneal Neovascularization	Altered Intercellular Communication	We conclude that corneal lymphangiogenesis develops after keratoplasty, and is strongly associated with hemangiogenesis, inflammation and the history of transplantation.	18617753
Inflammation, Carcinogenesis	Altered Intercellular Communication	COX-2 represents a key modulatory molecule in inflammation and carcinogenesis, and is known to be implicated in the positive regulation of growth and tumorigenesis.	18617777
Inflammation, Sample Size Calculation, Vascular Diseases	Altered Intercellular Communication	The results suggest that MIF might contribute to inflammation and vasculopathy in SSc.	18618071
Ocular Hypertension, Inflammation, Compressed structure	Altered Intercellular Communication	No significant ocular hypertension, clinically significant emulsification of the tamponade or inflammation developed during follow-up.	18618126
Facial paralysis, Optic Neuritis	Altered Intercellular Communication	Quantitative analysis of the facial nerve on the lesion side as well as the normal side, which allowed for more accurate measurement of facial nerve enhancement in patients with facial palsy, showed statistically significant correlation with the initial severity of facial nerve inflammation, although little prognostic significance was shown.	18618345
Inflammation, Dry Eye Syndromes	Altered Intercellular Communication	Therefore, mechanisms influencing protection of the ocular surface against inflammation and damage in different types of dry eye disease warrant further investigation particularly in relation to MUC1 genotype.	18619437
Inflammation, Edema	Altered Intercellular Communication	The main histological alterations were edema (100%), inflammation (81.48%), basal membrane (bm) thickening (77.77%), and vessel proliferation (75.92%).	18619781
Lymphoid hyperplasia, Acute inflammation	Altered Intercellular Communication	Pathologic analysis disclosed acute neutrophilic inflammation in 12 cases and lymphoid hyperplasia in 10 of the 24 appendices.	18622474
Inflammation, No metabolic abnormalities, Albuminuria, Atherosclerosis	Altered Intercellular Communication	Recent studies have shown that albuminuria accompanied by evidence of subclinical inflammation is more strongly associated with metabolic abnormalities and the development of atherosclerosis than albuminuria alone.	18624904
Communicable Diseases, Inflammation, Periodontal Diseases, Chronic Kidney Diseases	Altered Intercellular Communication	Periodontal disease is an infectious disease that appears to be an important cause of systemic inflammation in CKD patients.	18624938
TAO brand of troleandomycin, Inflammation, Thyroid associated opthalmopathies	Altered Intercellular Communication	The PPAR gamma transcription factor, is involved in both adipogenesis and inflammation, which have been implicated in the pathogenesis of thyroid-associated orbitopathy (TAO).	18624999
Inflammation	Altered Intercellular Communication	Despite a similar clinical improvement and reduction of synovial inflammation, antinucleosome IgM were induced by infliximab but not etanercept.	18625621
Inflammation, Anemia	Altered Intercellular Communication	PON1 reflected disease activity, inflammation severity, and anemia but not lipid peroxidation.	18626964
Gastrointestinal inflammation	Altered Intercellular Communication	Osteopontin as two-sided mediator of intestinal inflammation.	18627421
Gastrointestinal inflammation	Altered Intercellular Communication	However, its role in intestinal inflammation is currently unknown.	18627421
Gastrointestinal inflammation, Colitis	Altered Intercellular Communication	To identify the role of this mediator in intestinal inflammation, we analysed experimental colitis in OPN-deficient (OPN(-/-)) mice.	18627421
Inflammatory disease of mucous membrane, Colitis	Altered Intercellular Communication	In contrast to acute colitis, during chronic DSS-colitis, which is driven by a Th1 response of the lamina propria infiltrates, OPN(-/-) mice were protected from mucosal inflammation and demonstrated lower serum levels of IL-12 than WT mice.	18627421
Tissue damage, Inflammation, Gastrointestinal inflammation	Altered Intercellular Communication	Taken together, we postulate a dual function of OPN in intestinal inflammation: During acute inflammation OPN seems to activate innate immunity, reduces tissue damage and initiates mucosal repair whereas during chronic inflammation it promotes the Th1 response and strengthens inflammation.	18627421
Inflammation, Fibrosis Assessment, Chronic inflammation	Altered Intercellular Communication	Microscopic pathological examination revealed fibrinous debris with acute inflammation and organizing fibrosis with chronic inflammation, compatible with a vegetation.	18627635
Granulomatous inflammation	Altered Intercellular Communication	As this is a diagnosis of exclusion, other etiologies of granulomatous inflammation must be ruled out with tests and special stains.	18627737
Inflammatory disease of mucous membrane	Altered Intercellular Communication	A biopsy specimen showed a squamous mucosa with chronic submucosal inflammation and brown pigment.	18627755
Inflammation, Alopecia universalis	Altered Intercellular Communication	The principle of treating trachyonychia may involve regulating the differentiation of keratinocytes and/or reducing inflammation in the nail fold or nail matrix while treatment of alopecia universalis involves immunomodulation.	18627760
Inflammation, Interstitial Fibrosis Assessment, Honeycomb appearance	Altered Intercellular Communication	Histopathology findings range from focal peribronchiolar inflammation to diffuse interstitial fibrosis and honeycombing.	18628077
Inflammation, Primary malignant neoplasm, Chronic disease	Altered Intercellular Communication	Low-grade systemic inflammation is suggested to play a role in the development of several chronic diseases including cancer.	18628422
Inflammation	Altered Intercellular Communication	Higher levels of physical activity and lower adiposity have been associated with reduced levels of markers of systemic inflammation, such as C-reactive protein (CRP); however, reductions in CRP have not been consistently observed in randomized controlled trials of exercise.	18628422
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Adiponectin appeared to be a mediator of this association, but circulating biomarkers of inflammation, endothelial dysfunction, and fasting insulin did not explain this association.	18628567
Inflammation, Accessory tragus	Altered Intercellular Communication	Ultrasonography revealed a pretragal, hypoechoic mass, 10x8 mm in size, causing inflammation in the surrounding tissue.	18628648
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Circulating biomarkers of inflammation, antioxidant activity, and platelet activation are associated with primary combustion aerosols in subjects with coronary artery disease.	18629312
Inflammation, Cardiovascular morbidity	Altered Intercellular Communication	Biomarkers of systemic inflammation have been associated with risk of cardiovascular morbidity and mortality.	18629312
Inflammation	Altered Intercellular Communication	Results suggest that traffic emission sources of OCpri and quasi-ultrafine particles lead to increased systemic inflammation and platelet activation and decreased antioxidant enzyme activity in elderly people with CAD.	18629312
Inflammation, Fibrosis Assessment, Ancriviroc, Hepatitis C, Alcohol abuse	Altered Intercellular Communication	These findings suggest that ACA is induced by chronic HCV infection in association with HLA DR-8, and that CH-C patients with ACA exhibit more severe hepatic fibrosis and inflammation than CH-C patients without ANA.	18629643
Lip and Oral Cavity Carcinoma, Malignant Neoplasms	Altered Intercellular Communication	In light of the recently found contribution of angiogenic and inflammation-related factors to malignancies, this study investigated the possible association of the angiotensinogen gene (AGT) with increased risk of oral cancer.	18630525
Inflammation	Altered Intercellular Communication	The keratinocytes secrete high amounts of C3 after stimulation with pro-inflammatory cytokines, which may play a functional role in skin inflammation.	18631248
Autoimmune Diseases, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Our findings are consistent with the possibility of an autoimmune and/or innateimmune component in the pathogenesis of T2D: NK receptors with chronic inflammation in obese and genetic interactions with G1M allotype in T2D non-obese possibly mediating autoimmunity.	18632158
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	Vascular 18F-FDG uptake marker represents inflammation in atherosclerotic lesions, but whether inflammation can be reversed by risk-modifying interventions has not, to our knowledge, been demonstrated.	18632820
Refractory anemias, Inflammation	Altered Intercellular Communication	SF MIA levels were lower in RA than in SpA despite similar levels of overall synovial inflammation.	18633128
Refractory anemias, Inflammation	Altered Intercellular Communication	Further analysis indicated that these levels were inversely correlated with the degree of joint inflammation in RA, but not in SpA, and that the levels of TNFalpha and IL1beta were significantly increased in RA versus SpA.	18633128
Refractory anemias, Arthritis	Altered Intercellular Communication	The decreased levels of MIA in the inflamed RA joint and the coregulation of MIA and cartilage matrix molecules by proinflammatory cytokines indicate that joint inflammation in RA not only drives accelerated cartilage degradation but also suppresses cartilage anabolism.	18633128
Inflammation, Hypertension, CTCAE, Metabolic Syndrome X	Altered Intercellular Communication	The role of adiponectin, a marker of the metabolic syndrome, on the pathogenesis of hypertension in comparison with markers of adipose tissue mass (leptin) and inflammation (high-sensitivity C-reactive protein [hs-CRP]) remains to be clarified.	18633174
Uremia, Inflammation, Muscular Atrophy	Altered Intercellular Communication	Our results support the hypothesis that uremia with inflammation, but not uremia per se, inhibits downstream growth hormone signaling contributing to muscle atrophy.	18633341
Uremia, Inflammation, Muscular Atrophy	Altered Intercellular Communication	Our results support the hypothesis that uremia with inflammation, but not uremia per se, inhibits downstream growth hormone signaling contributing to muscle atrophy.	18633341
Uremia, Inflammation, Muscular Atrophy	Altered Intercellular Communication	Our results support the hypothesis that uremia with inflammation, but not uremia per se, inhibits downstream growth hormone signaling contributing to muscle atrophy.	18633341
Inflammation, Phlegmon, Pyoderma Gangrenosum, Bacterial Infections	Altered Intercellular Communication	Pyoderma gangrenosum often starts as pustule, nodule or local inflammation which suggest the diagnosis of bacterial infection of skin such as furuncle or phlegmon so patients with early symptoms could be refered to surgical units.	18634250
Inflammation, Tuberculosis	Altered Intercellular Communication	Tuberculosis process found in the area of middle ear and palatine tonsils imitated chronic, non-specific inflammation and in the case concerning the ear was the only location of the illness.	18634293
Inflammation, Coronary heart disease	Altered Intercellular Communication	PON1 status is influenced by oxidative stress and inflammation in coronary heart disease patients.	18634772
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Oxidative stress in CHD patients is maintained by systemic low-grade inflammation, which results in PON1 enzymatic activity exhaustion.	18634772
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Interestingly patients with cancer were less likely to have inflammation on initial biopsy (p = 0.05).	18635220
Inflammation, Kidney Failure, Chronic Kidney Diseases	Altered Intercellular Communication	Elevated visfatin in CKD patients may be due to renal failure and/or inflammation.	18635422
Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	Adipocytokines related to adhesion molecules might support the importance of inflammation/endothelial cell injury in the pathogenesis of atherosclerosis and its consequences in CKD.	18635422
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	High-density lipoprotein (HDL) antiatherogenic functions seem to be diminished during inflammatory conditions such as rheumatoid arthritis (RA).	18635596
Inflammation	Altered Intercellular Communication	Since chemokines and adhesion molecules play an important role in the positioning of leucocytes at sites of inflammation, we tested the hypothesis that the differential expression and function of chemokine and/or adhesion molecules explains why CD4(+) T cells accumulate within perivascular cuffs, whereas CD8(+) T cells distribute diffusely within the tissue.	18635598
Inflammation, Injury of liver, Endotoxemia	Altered Intercellular Communication	During repeated experimental endotoxemia in healthy volunteers, TNF-alpha and IL-6 levels increased from undetectable levels to 1,425 (474-1,949) and 1,739 (989-2,047) pg mL, respectively, whereas GSTA1-1 levels did not exceed the normal range, indicating that no (sub)clinical liver injury occurs in this model of inflammation.	18636040
Inflammation, Raynaud Phenomenon, Arthralgia, Rheumatoid Factor, Rheumatoid Arthritis	Altered Intercellular Communication	At the age of 31, she was diagnosed with rheumatoid arthritis on account of her diffuse joint pain and inflammation, elevated rheumatoid factor (RF) and Raynaud's phenomenon.	18636673
Squamous cell carcinoma, Hyperplasia, Esophagitis, Ocular melanosis	Altered Intercellular Communication	Melanocytic hyperplasia (melanocytosis) has previously been recognized as an occasional reactive lesion, which can accompany esophageal inflammation and invasive squamous carcinoma.	18636677
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Monocyte chemoattractant protein-1 plays a dominant role in the chronic inflammation observed in Alzheimer's disease.	18637012
Inflammation, Data types - Address	Altered Intercellular Communication	Our data support previous work on significant increases in IL-6 and IL-8 in AD but indicate that MCP-1 may play a more dominant role in chronic inflammation in AD.	18637012
Fibrosis Assessment, Intrahepatic Route of Drug Administration	Altered Intercellular Communication	A continuous 13C methacetin breath test for noninvasive assessment of intrahepatic inflammation and fibrosis in patients with chronic HCV infection and normal ALT.	18638013
Fibrosis Assessment, Hepatitis C, Intrahepatic Route of Drug Administration	Altered Intercellular Communication	To assess its role in identifying intrahepatic inflammation and fibrosis in NALT patients, we tested 100 patients with untreated chronic HCV infection, and 100 age- and sex-matched healthy volunteers using (13)C MBT following ingestion of 75 mg methacetin.	18638013
Intrahepatic Route of Drug Administration	Altered Intercellular Communication	A proprietary algorithm to differentiate intrahepatic inflammation within chronic HCV patients with NALT achieved an area under the curve (AUC) of 0.90.	18638013
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The continuous BreathID(13)C MBT is an accurate tool for measuring the degree of inflammation and fibrosis in patients with chronic HCV infection and NALT.	18638013
Inflammation	Altered Intercellular Communication	Eosinophilic dust, flame figures and granulomatous inflammation were not seen.	18638225
Inflammation, Necrobiosis Lipoidica, Granuloma Annulare, Mucinoses	Altered Intercellular Communication	The initial histopathology revealed dermal and subcutaneous inflammation with interstitial histiocytes and mucinosis suggestive of either granuloma annulare or necrobiosis lipoidica.	18638228
Inflammation, Aortic Rupture	Altered Intercellular Communication	The clinical presentation of large-vessel GCA is highly variable, from systemic inflammation to aortic rupture.	18639414
methionine, Inflammation	Altered Intercellular Communication	Lobular inflammation improved from baseline in the MET group (P=0.003).	18640473
ARCN1 gene, Inflammation, Pulmonary Emphysema, Chronic Obstructive Airway Disease, Airway Obstruction, Bronchitis	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD), characterized by airway obstruction and inflammation leading to chronic bronchitis and emphysema, is an important cause of morbidity, mortality, and increased health care utilization and expenditures.	18640475
vascular inflammations	Altered Intercellular Communication	ICG leakage is a sign of vascular inflammation and reflects the severity of the disease.	18641582
Inflammation	Altered Intercellular Communication	The final (healed) stage has minimal cellular inflammation with occlusive intimal thickening.	18645302
Conjunctivitis	Altered Intercellular Communication	The relevance of these conjunctival cytologic features to the various factors of prosthesis care or conjunctival inflammation was analyzed.	18645434
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Sarcoid-like granulomatous orbital inflammation induced by interferon-alpha treatment.	18645440
Granulomatous inflammation	Altered Intercellular Communication	Histopathologic evaluation of bilateral lacrimal gland biopsy specimens revealed granulomatous inflammation.	18645440
Blepharitis, Traumatic injury	Altered Intercellular Communication	There was no prior history of trauma, surgery, or eyelid inflammation.	18645448
Jejunal ulcer, Gastrointestinal inflammation, Intestines, Small	Altered Intercellular Communication	To exclude the possibility of small bowel involvement the patient underwent video capsule endoscopy that showed a diffuse and extensive intestinal inflammation with multiple linear, irregular-shaped jejunal ulcerations, and apthae.	18645536
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	Surgical technique and systemic inflammation influences long-term disease-free survival following hepatic resection for colorectal metastasis.	18646038
Waldenstrom Macroglobulinemia	Altered Intercellular Communication	Histologic analysis revealed a pancreas with sclerotic ducts and surrounding lymphoplasmacytic inflammation most consistent with lymphoplasmacytic sclerosing pancreatitis (LPSP).	18646484
Steatohepatitis, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	The prevalence of hepatic steatosis and its trend during the study period were determined, and the relationships among their hepatic steatosis with clinical data, serum biochemistry, HBV viral load, and the degree of liver inflammation and fibrosis stage were studied.	18647531
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Similarly, prevalence of steatosis was higher in patients with inflammation grade 1 (19.8%) and fibrosis stage 1 (19.1%) than in patients with inflammation grade 0 (10.3%), grade 2 (11.5%), grade 3 (9.3%) and grade 4 (7.3%), and in patients with fibrosis stage 0 (10.8%), stage 2 (13.3%), stage 3 (7.1%) and stage 4 (7.4%), respectively.	18647531
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	It is also not related to the degrees of liver inflammation and fibrosis.	18647531
Granulomatous inflammation, Fibrosis Assessment, Infection by Cryptococcus neoformans, Tuberculosis	Altered Intercellular Communication	Among the benign lesions, 12 were granulomatous inflammation, including 10 tuberculosis lesions and two cryptococcosis lesions, and three were focal fibrosis.	18647920
Granulomatous inflammation, Chronic granulomatous disease, Tuberculosis	Altered Intercellular Communication	Delayed FDG PET is not useful for differentiating benign and malignant pulmonary nodules with an initial mean SUV less than 2.5 in geographic regions with epidemic granulomatous disease such as tuberculosis or in patients at high risk of granulomatous inflammation.	18647920
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	About thirty international specialists were invited to share their experience and thoughts covering the main topics of: A) pancreatic diabetes (type 3c); B) chronic inflammation of the pancreas.	18648151
Inflammation, Pancreatitis, Pancreatitis, Chronic, Pancreatic Diseases, Autoimmune Diseases, Chronic obstruction, Cholelithiasis	Altered Intercellular Communication	Session B included presentations about the frequency of chronic inflammation of the pancreas and therapeutical implications, the role of ACE in the pancreas, genomics and the metabolic hypothesis of chronic pancreatitis, nutritional aspects of pancreatic diseases, the stellate cell concept, autoimmunity, genetic background of chronic pancreatitis and the hypothesis of chronic obstruction induced by gallstone disease.	18648151
Inflammation, Complex Regional Pain Syndromes, Hyperalgesia	Altered Intercellular Communication	We propose three pathomechanisms of CRPS I, which follow a distinct time course: Thermal hyperalgesia, observed in acute CRPS, indicates an ongoing aseptic peripheral inflammation.	18648647
Inflammation, Complex Regional Pain Syndromes	Altered Intercellular Communication	PHS in acute CRPS I indicates that both inflammation and degeneration are present, whilst in chronic CRPS I, the pathomechanism of degeneration dominates, signalled by the absence of PHS.	18648647
Inflammation, Ileitis, Crypt, Lobular Endocervical Glandular Hyperplasia, Plasmacytosis	Altered Intercellular Communication	The diagnostic criteria of chronic ileitis included crypt distortion and inflammation, plasmacytosis in the lamina propria, ulceration, and/or pyloric gland metaplasia.	18648739
Intercellular Communication Process, Erectile dysfunction	Altered Intercellular Communication	Impaired intercellular communication as suggested by decreased expression of desmoplakin may be an important feature of contractile dysfunction in HM.	18649053
Inflammation, Blood Clot, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	The development and progression of atherosclerosis comprises various processes, such as endothelial dysfunction, chronic inflammation, thrombus formation, and lipid profile modification.	18649055
Granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	Histopathology of excised cocoon membrane revealed granulomatous inflammation consistent with tuberculosis.	18649113
Inflammation, Prostatic Diseases, Prostate, Edema, Prostatic Adenoma	Altered Intercellular Communication	The prostatic extract has an organ-tropic action in relation to the prostate: inhibits proliferative activity of the cells leading to suppression of prostatic adenoma development, reduces edema and activity of inflammation in prostatic diseases.	18649662
Refractory anemias, Inflammation	Altered Intercellular Communication	Paradoxically, RA patients have elevated numbers of circulating CD4(+)CD25(high) T cells, however, the inflammation is still ongoing.	18649874
Refractory anemias, Inflammation	Altered Intercellular Communication	In addition, the GITR-GITR-L system was activated in RA patients, which might lead to diminish suppressive activity of Treg cells and/or lead to resistance of activated effector T cells to suppression by Treg cells, thus, contributing to the ongoing inflammation in RA patients.	18649874
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In addition, the risk of tissue inflammation was four times lower in hemodialysis patients (odds ratio = 0.23, P < 0.004), and severe inflammatory activity on biopsy was the only independent risk factor for fibrosis (P < 0.001).	18650408
Inflammation, Normocytic normochromic anemia	Altered Intercellular Communication	Blood tests demonstrated increased parameters for systemic inflammation and mild normochromic normocytic anemia.	18651363
vascular inflammations, Vasculitis, CTCAE	Altered Intercellular Communication	On the other hand, the clinical picture of CES resembles systemic vasculitis, and there is a controversy regarding the association between CES and glomerular or vascular inflammation.	18651554
Inflammation, Nasal Polyps	Altered Intercellular Communication	Nasal polyps, according to many authors, generate as a result of chronic inflammation process with activation of cytokines, immunological reaction mediators that regulate proliferation, differentiation and cell apoptosis.	18652146
Inflammation, Nasal Polyps	Altered Intercellular Communication	The evaluation of 22,283 genes transcriptions showed that in most cases nasal polyps tissue reflect classification connected with dominant inflammation cells infiltration.	18652146
Inflammation, Nasal Polyps	Altered Intercellular Communication	The data obtained suggest that molecular mechanisms may influence on the promotion and kind of inflammation process as well as the clinical course of nasal polyps.	18652146
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Appendicitis is an inflammation of the appendix, the etiology of which is still poorly understood.	18652981
Rheumatoid Arthritis, Asthma, Coronary Arteriosclerosis	Altered Intercellular Communication	Predictive factors of individual procedures included: urine retention (transurethral resection of the prostate); extended duration of operation and asthma (hysterectomy); acute admissions and extended duration of operation (cholecystectomy); and warfarin type drugs, ethanol abuse, failed prostheses, GI ulcer/inflammation, rheumatoid arthritis, and ischaemic heart disease (hip and knee joint arthroplasty).	18653583
Inflammation, Carotid Intima-Media Thickness, Atherosclerosis	Altered Intercellular Communication	The genotypes also had no effect on the marker of inflammation (C-reactive protein) or atherosclerosis (mean and maximum carotid intima-media thickness).	18654002
Inflammation, Atherosclerosis	Altered Intercellular Communication	Resistin, a novel adipocytokine, has been suggested as representing a link between metabolic signals, inflammation and atherosclerosis.	18654008
Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation, an independent cardiovascular disease risk factor is common in patients with chronic kidney disease.	18656467
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We hypothesized that in chronic kidney disease, SOCS expression in peripheral blood mononuclear cells is increased, and related to inflammation and renal function.	18656467
Sinusitis, Hypoxia	Altered Intercellular Communication	Local hypoxia within the sinus is believed to aggravate sinus inflammation.	18656716
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	There is a strong link between inflammation and endothelial function, in patients with atrial fibrillation.	18657327
Chronic prostatitis, prostatitis	Altered Intercellular Communication	The evaluation of markers of prostatic inflammation and function of the prostate gland in patients with chronic prostatitis.	18661262
Inflammation	Altered Intercellular Communication	C. trachomatis prostate infection was detected in 17.4% of the patients and all of these men had higher inflammation parameters and lower citric acid concentrations.	18661262
Inflammation, prostatitis	Altered Intercellular Communication	C. trachomatis prostate inflammation was accompanied by an increase in inflammation markers and a decrease in citric acid concentration.	18661262
Parkinson Disease, Hypotension, Orthostatic	Altered Intercellular Communication	Generalized and neurotransmitter-selective noradrenergic denervation in Parkinson's disease with orthostatic hypotension.	18661549
ETV3 wt Allele	Altered Intercellular Communication	As testosterone progressively dominates the hormonal milieu during the menopausal transition, the prevalence of MetS increases, independent of aging and other important covariates.	18663170
Pain Distress Question, Inflammation, Spasm	Altered Intercellular Communication	The goals of a pharmacological treatment for acute low back are, therefore, not only the relief of pain, but also the reduction of muscle spasm and inflammation, since nociception often results from local secondary inflammation and muscle spasm.	18663343
Inflammation, Myocardial Ischemia	Altered Intercellular Communication	Inflammation and disturbances of the hemostatic system may play a role in pathogenesis and complications of ischemic heart disease.	18663903
Inflammation, Sleep Disorders	Altered Intercellular Communication	Increased inflammation has been noted in sleep disorder patients with normal renal function.	18664587
HD Term Type, Sleep Quality Question, Inflammation, Dyssomnias	Altered Intercellular Communication	Our study demonstrated severe impairment of sleep quality in HD patients and corroborated the role of inflammation in the pathogenesis of sleep disturbance.	18664587
Inflammation, Observation Method - Coagulation, Heat Stroke	Altered Intercellular Communication	Leukocyte activation: the link between inflammation and coagulation during heatstroke.	18664784
Inflammation, Observation Method - Coagulation, Heat Stroke	Altered Intercellular Communication	The mechanisms linking severe inflammation and coagulation during heatstroke are poorly understood.	18664784
Inflammation, Heat-Shock Response	Altered Intercellular Communication	High circulating levels of some inflammation and stress mediators (interleukin-6, -8, C5a, interleukin-1 receptor antagonist, heat shock protein 60 and 70) were observed.	18664784
Inflammation, Disseminated Intravascular Coagulation	Altered Intercellular Communication	The degrees of inflammation and disseminated intravascular coagulation are correlated with clinical severity.	18664784
Sepsis, Inflammation	Altered Intercellular Communication	Differential expression of toll-like receptor genes: sepsis compared with sterile inflammation 1 day before sepsis diagnosis.	18665047
Sepsis, Inflammation, Critical Illness	Altered Intercellular Communication	This study was designed to evaluate differential expression of genes for TLR and associated signal transduction molecules in critically ill patients developing sepsis compared with those with sterile inflammation.	18665047
Sepsis, Inflammation, Critical Illness	Altered Intercellular Communication	The TLR and downstream signaling genes are differentially expressed in critically ill patients developing sepsis compared with those with sterile inflammation.	18665047
Gastric mucosa	Altered Intercellular Communication	These cells have not been sufficiently studied in context to H. pylori-induced inflammation in human gastric mucosa.	18665940
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To examine the impact of inflammation, insulin-like growth factor (IGF-1) and its regulating binding protein (IGFBP-1) on lean body mass (LBM) in patients with rheumatoid arthritis (RA).	18666027
Inflammation	Altered Intercellular Communication	High-sensitivity C-reactive protein is an important biomarker of systemic inflammation.	18667998
Inflammation, Fever, Typhlitis, Abdominal Pain	Altered Intercellular Communication	Typhlitis is necrotizing inflammation of the cecum manifested by febrile right lower quadrant abdominal pain.	18668001
Refractory anemias, Rheumatoid Arthritis, Inflammation, Infection	Altered Intercellular Communication	Rheumatoid arthritis (RA) is associated with increased frequency of and mortality from infections, which may be related to host factors, RA itself, inflammation, or medication side effects.	18668604
Fibrous, Inflammation, Neoplasms	Altered Intercellular Communication	Needle biopsy from the tumour in the orbit revealed only fibrous tissue with signs of chronic inflammation.	18669090
Inflammation, Malignant neoplasm of lung	Altered Intercellular Communication	To differentiate between benign and malignant lesions of the lung, 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) has limitations such as a lower specificity in cases of non-specific inflammation.	18670862
Cessation of life, Inflammation, Laryngospasm	Altered Intercellular Communication	Given the presence of mucosal inflammation extending into the vocalis muscle of the larynx without associated significant narrowing of the laryngotracheal airway lumen, we propose his death was a result of a laryngospasm, perhaps mediated by immune responses.	18671453
atherosclerotic	Altered Intercellular Communication	Statins are known as partial inhibitors of atherosclerotic inflammation on CSAV.	18671964
Inflammation, Congestive heart failure	Altered Intercellular Communication	The relationship between markers of inflammation and of ECM remodeling, and their influence on functional status and outcomes has not been examined in a large cohort of CHF patients.	18672194
methyldopa, Uveitis	Altered Intercellular Communication	We describe acute intraocular inflammation after intravitreous injection of bevacizumab for the treatment of neovascular AMD.	18672291
methyldopa, Uveitis	Altered Intercellular Communication	We retrospectively reviewed cases of acute intraocular inflammation after intravitreous injection of bevacizumab for the treatment of neovascular AMD.	18672291
Inflammatory abnormality of the eye	Altered Intercellular Communication	There were associated signs of ocular inflammation in the anterior and posterior segments of the eye.	18672291
methyldopa, Uveitis	Altered Intercellular Communication	Intravitreous injection of bevacizumab for the treatment of neovascular AMD may be associated with acute intraocular inflammation.	18672291
Inflammation, Endophthalmitis, CTCAE, Intraocular Lymphoma, Granulomatous inflammation	Altered Intercellular Communication	We categorized the results of vitreous cytologic examination into 6 major categories: acute inflammation consistent with endophthalmitis (n = 33), primary intraocular lymphoma (PIOL; n = 14), granulomatous inflammation (n = 41), mixed chronic nonspecific inflammation (n = 76), hypocellular specimens (n = 50), and miscellaneous specimens (n = 64).	18672292
Inflammation, Fatigue	Altered Intercellular Communication	Inflammation and comorbidities play a role in the dialysis fatigue.	18672416
Inflammation, Periodontal Diseases	Altered Intercellular Communication	Bringing light to the heat: "inflammation and periodontal diseases: a reappraisal".	18672978
Inflammation, Disease	Altered Intercellular Communication	With the discovery of the mechanism of action of aspirin, scientists began to develop new strategies for treating diseases that focused on controlling inflammation.	18673010
Communicable Diseases, Inflammation, Periodontal Diseases, Blood Circulation	Altered Intercellular Communication	At the end of the 20th century, an old concept in medicine and dentistry reappeared: that the infection and inflammation of periodontal disease in the mouth could reach distant sites via the bloodstream.	18673010
Alveolar damage, Interstitial inflammation	Altered Intercellular Communication	Diffuse alveolar damage, including interstitial inflammation, intraalveolar granulocyte infiltration, and hyaline membrane formation, were not identified in either case.	18673344
Carcinogenic Chlorinated Hydrocarbon, Complete atrioventricular block, Inflammation	Altered Intercellular Communication	Liver-targeted regulatory T cells present similarly in CHB and CHC, but their relationship with the effector cell population, the inflammation grade or the viral load is different between CHB and CHC.	18673437
Acute Kidney Injury, CTCAE, Inflammation	Altered Intercellular Communication	In adults, early postoperative measurement of urinary IL-18 appears not to be valuable in identifying patients who develop acute kidney injury after cardiac surgery, but rather represents a nonspecific marker of cardiopulmonary bypass-associated systemic inflammation.	18673539
Allergic, Inflammation, Dermatitis, Irritant, Atopy, Dermatitis	Altered Intercellular Communication	The most common differential diagnoses for patients presenting with lip dermatitis or inflammation include atopic, allergic, and irritant contact dermatitis.	18674455
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation in lone atrial fibrillation: new insights by coronary sinus thermography.	18674828
Inflammation	Altered Intercellular Communication	Patients with AF have increased myocardial heat production, which is correlated to the systemic inflammation.	18674828
Inflammation, Thrombosis, Lip and Oral Cavity Carcinoma	Altered Intercellular Communication	Gene polymorphisms related to angiogenesis, inflammation and thrombosis that influence risk for oral cancer.	18674955
Inflammation, Thrombosis, Squamous cell carcinoma, SERPINB3 wt Allele	Altered Intercellular Communication	Genetic association studies have implicated functional DNA polymorphisms in genes encoding factors related to angiogenesis, inflammation and thrombosis with increased risk for oral squamous cell carcinoma (OSCC).	18674955
Osteopenia, Colitis	Altered Intercellular Communication	We evaluated the contribution of colonic inflammation to osteopenia and its mechanism in a murine colitis model.	18675386
Colitis	Altered Intercellular Communication	The degree of colonic inflammation was assessed by a clinical disease activity index, and colonic mucosal myeloperoxidase activity.	18675386
Inflammatory disease of mucous membrane	Altered Intercellular Communication	The decrease in indices of bone mass, structure and formation are directly linked to the degree of colonic mucosal inflammation.	18675386
Granulomatous inflammation, Amoeba genus	Altered Intercellular Communication	Review of the skin biopsy revealed the presence of amoebic trophozoites within a granulomatous inflammation.	18675522
Inflammation	Altered Intercellular Communication	Mechanisms of immediate postoperative movement-evoked pain may differ from those in effect at later time points after which tissue inflammation and spinal sensitization develop.	18675741
Inflammation, Anemia, hepcidin	Altered Intercellular Communication	In contrast, patients with the anemia of inflammation have higher hepcidin levels than sex- and age-matched controls.	18676162
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Serum MMP-9 has a modest association with incident CHD in the general population, which is not independent of cigarette smoking exposure and circulating markers of generalized inflammation.	18676684
Icterus, Inflammation, Abdominal Pain	Altered Intercellular Communication	About two thirds of the patients in group I had jaundice, while abdominal pain related to inflammation was the commonest symptom in groups II and III.	18677540
Inflammation	Altered Intercellular Communication	Obestatin appears to decrease food intake and appetite, and its potential role in inflammation is not yet clear.	18677577
Parkinson Disease, Inflammation, palladium, Nerve Degeneration	Altered Intercellular Communication	Higher levels of proinflammatory cytokines are found in Parkinson's disease (PD) patient's brains and inflammation is thought to be a major contributor to the neurodegeneration.	18678243
Parkinson Disease, Inflammation	Altered Intercellular Communication	Inflammation as a causative factor in the aetiology of Parkinson's disease, Br.	18678243
Inflammation, Spondylitis, Collagen Diseases	Altered Intercellular Communication	Ankylosing spondylitis (AS) is a common, largely genetically determined, rheumatic disease that is characterised by spinal inflammation and new bone formation.	18678577
Inflammation	Altered Intercellular Communication	This supports the role of persistent inflammation in the pathogenesis of AS.	18678577
Inflammation, Overweight	Altered Intercellular Communication	The increase of fatty acid-binding protein aP2 in overweight and obese children: interactions with dietary fat and impact on measures of subclinical inflammation.	18679408
Inflammation, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	In adults, circulating aP2 may link obesity, inflammation and the metabolic syndrome, but there are few data in children.	18679408
Communicable Diseases, Inflammation	Altered Intercellular Communication	High mobility group box 1 (HMGB1) is a versatile protein with intranuclear and extracellular functions that is involved in numerous biological and pathological processes, such as transcription, DNA repair, and response to infection and inflammation.	18680137
Inflammation	Altered Intercellular Communication	The current study indicates that colonocytes do not respond to cytokine exposure and inflammation by an increased vulnerability, as previously thought.	18680199
Inflammation	Altered Intercellular Communication	Colonocytes seem to activate cytoprotective programs in response to inflammation.	18680199
Inflammation	Altered Intercellular Communication	Apart from supporting the regeneration process during inflammation, this response could additionally cause an increased susceptibility to neoplastic transformation.	18680199
Inflammation, "Marjolins ulcer", Neoplasms	Altered Intercellular Communication	Marjolin's ulcer is defined as a tumor arising from a chronic wound, scar or chronic inflammation.	18681267
Inflammation, Ulcer	Altered Intercellular Communication	According to different grades of DF, there were different strategies in dealing with the accompanied inflammation and ulcer.	18681279
No metabolic abnormalities, Polycystic Ovary Syndrome	Altered Intercellular Communication	Obese women with polycystic ovary syndrome (PCO), characterized by hormonal and metabolic abnormalities, are thought to be at particularly increased cardiovascular risk.	18682502
Asthma, allergic inflammation	Altered Intercellular Communication	Physical training does not increase allergic inflammation in asthmatic children.	18684843
Inflammation, Asthma	Altered Intercellular Communication	Training did not increase inflammation in children with persistent asthma, and may have decreased both total and allergen-specific immunoglobulin E levels.	18684843
Inflammation, Vitreous opacities	Altered Intercellular Communication	Ophthalmoscopy revealed inflammation in the anterior chamber and vitreous opacities in both eyes.	18685258
Inflammation, Brain Injuries	Altered Intercellular Communication	Proinflammatory and anti-inflammatory cytokines may play a pivotal role in cerebral inflammation, which is implicated in the development of brain injury.	18685925
Congenital Abnormality, Tracheobronchial structure, Neoplasms, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Among 70 patients who underwent bronchoscopy, 67 patients had pathological abnormalities from severe airway mucosal inflammation, tracheobronchial cartilage destruction, and tracheobronchial wall collapse (n = 35) to neoplasms (n = 32).	18686615
Tuberculosis, Neoplasms, Necrotizing granulomatous inflammation, polychondritis, Amyloidosis	Altered Intercellular Communication	Among 60 patients who underwent pathological examinations, the pathological changes were consistent with amyloidosis (n = 16), relapsing polychondritis (n = 5), tuberculosis (n =4), tumors (n = 25), or chronic granulomatous inflammation of mucosa (n = 10).	18686615
Inflammation, Organ Dysfunction Scores, Traumatic injury	Altered Intercellular Communication	The AOX intervention did not reduce early organ dysfunction but significantly reduced the inflammatory response in cardiac surgery and trauma patients, which may prove beneficial in conditions with an intense inflammation.	18687132
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Much research evidence supports the hypothesis that chronic, low-grade inflammation related to innate immunity may play an important role in the pathophysiology of type 2 diabetes mellitus (T2DM).	18688176
Icterus, Inflammation, Hepatobiliary Disorder	Altered Intercellular Communication	Clinical signs such as jaundice may not be reliable indicator of ongoing inflammation or the presence of an ongoing liver disease.	18689142
Inflammatory Bowel Diseases, Inflammation, Primary malignant neoplasm, Colorectal Carcinoma	Altered Intercellular Communication	Patients with inflammatory bowel diseases are at increased risk for colorectal cancer, but the molecular mechanisms linking inflammation and cancer are not well defined.	18689872
Inflammation, SLC25A20 gene	Altered Intercellular Communication	mAbGB3.1 administration markedly reduces chronic inflammation and tumorigenesis in the mouse model of CAC and RAGE-deficient mice are resistant to the onset of CAC.	18689872
Carcinogenesis	Altered Intercellular Communication	These findings show that RAGE, carboxylated glycans and S100A8/A9 play essential roles in tumor-stromal interactions, leading to inflammation-associated colon carcinogenesis.	18689872
Granulomatous inflammation	Altered Intercellular Communication	Histological findings revealed granulomatous inflammation around hair follicles and positive fungal elements by PAS and Grocott staining in these follicles.	18689972
Inflammation, Edema	Altered Intercellular Communication	The 3 patients had MRI findings consisting of inflammation and/or edema in the spinous processes and surrounding soft tissues.	18690283
Inflammation, Primary malignant neoplasm, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Stepwise logistic regression analysis revealed that obesity, metabolic syndrome, cancer, intake of six or more drugs, acute inflammation and nonsmoking were associated with hypogonadal testosterone levels.	18691272
Inflammation, Ulcerative Colitis-Associated Colorectal Adenocarcinoma	Altered Intercellular Communication	Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers.	18691581
Inflammation, Colorectal Carcinoma, Somatic mutation	Altered Intercellular Communication	Our findings indicate that proinflammatory cytokine-mediated aberrant expression of AID in colonic epithelial cells is a genotoxic factor linking inflammation, somatic mutations, and colorectal cancer development.	18691581
Inflammation, Hepatitis B	Altered Intercellular Communication	It is suggested that the plasma levels of uPA and uPAR are closely related to the degree and period of inflammation in patients with acute or chronic hepatitis B, and that uPA and uPAR might be important indicators for disease progression.	18691743
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Chronic subclinical inflammation may be involved in the pathogenesis of Type 2 diabetes.	18691786
Inflammation	Altered Intercellular Communication	We examined whether elevated WBC count, a marker of inflammation, was associated with worsening of glucose tolerance among Chinese population aged 40 years and over.	18691786
Inflammation	Altered Intercellular Communication	This is supported by the negative association between plaque inflammation and circulating progenitor cells before endarterectomy.	18692349
Inflammation, Anemia	Altered Intercellular Communication	Anemia, nutritional status, and inflammation in hospitalized elderly.	18692363
Inflammation, Cardiovascular Diseases, Atherosclerosis	Altered Intercellular Communication	Smoking increases the risk of cardiovascular disease and inflammation plays a key role in the process of atherosclerosis.	18692847
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Inflammation may be a potential mechanism by which smoking promotes atherosclerotic disease.	18692847
Inflammation, Hematoma, Communicable Diseases, Seroma, Erythema	Altered Intercellular Communication	Seventeen (68%), 13 (52%), 8 (32%), 5 (20%) and 2 (8%) patients had erythema, seroma, inflammation, hematoma and sever infection, respectively.	18692927
vascular inflammations, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Systemic lupus erythematosus (SLE) is characterized by immune complex deposits and subsequent vascular inflammation in many organs.	18693542
Inflammation, Cardiac complication, Malnutrition, Atherosclerosis	Altered Intercellular Communication	It is concluded that our patients on maintenance haemodialysis have significantly low BMI, total Cholesterol, LDL-C and Non-HDL-C depicting malnutrition leading to inflammation, accelerated atherosclerosis process and cardiovascular complications.	18693593
Ichthyosis Bullosa of Siemens, Irritable Bowel Syndrome	Altered Intercellular Communication	One of the several possible causes of irritable bowel syndrome (IBS) is thought to be low-grade mucosal inflammation.	18694443
Pain Distress Question, Cystitis, Interstitial Cystitis, Dysuria, Lupus Erythematosus	Altered Intercellular Communication	A 20-year-old woman with systemic lupus erythematosus presented with dysuria, urinary frequency and suprapubic pain and was found to have a chronic interstitial cystitis, a chronic inflammation of the bladder wall, mostly affecting middle-aged women.	18696074
Inflammation, Bartonella henselae	Altered Intercellular Communication	The diagnosis could be made serologically: IgG and IgM antibodies against Bartonella henselae were highly positive in the immunofluorescence test and the values for inflammation were also strongly increased.	18696078
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Angiogenesis and inflammation are the 2 major stroma reactions in colorectal carcinoma (CRC).	18697200
Cessation of life, Inflammation, Cardiomyopathies	Altered Intercellular Communication	Vascular endothelial growth factor appears to be in the pathway whereby inflammation and nitric oxide inhibition lead to cardiomyopathy and death in hemodialysis patients.	18698224
ACSM3 gene, vascular inflammations	Altered Intercellular Communication	The study's hypothesis is that cisternal cerebral spinal fluid (CSF) from patients after SAH may cause Ca(2+) oscillations which induce these modes of vascular inflammation in an in vitro model of human cerebral endothelial cells (HCECs).	18698333
Inflammation	Altered Intercellular Communication	Inflammation may play a causal role via upstream effectors rather than the downstream marker CRP.	18700811
Refractory anemias, Inflammation, Bone and Cartilage Funding	Altered Intercellular Communication	The role of inhibitory and activating NK cell receptor genes might contribute to chronic inflammation and destruction of bone and cartilage in RA.	18700876
Lymphangitis	Altered Intercellular Communication	CMV inclusions were seen in secretory cells of the prostatic glands, endothelial cells of small vessels, and prostatic stromal cells associated with a dense lymphoid inflammation.	18701513
Refractory anemias, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Low levels of inflammation may be sufficient for accelerated atherogenesis and an excess risk of cardiovascular disease in RA.	18701555
Cessation of life, Comorbidity	Altered Intercellular Communication	Unadjusted, case mix-adjusted (demographics, comorbidity, and Kt/V), and malnutrition-inflammation complex syndrome-adjusted models, the death rate ratio for the paricalcitol/PTH index groups, were 0.99, 0.95, and 0.92.	18701614
Inflammation, Specimen Type - Fistula, Dental caries, Specimen Source Codes - Abscess	Altered Intercellular Communication	This occurs particularly when caries progresses into pulpal inflammation and results in abscess or fistula formation (AFF).	18701824
Inflammation, Asthma	Altered Intercellular Communication	Pathological studies have established that eosinophilic inflammation is important especially in mild to moderate asthma, thus providing a rationale for ICS treatment.	18701970
Inflammation, Asthma	Altered Intercellular Communication	We have increasing evidence from all age groups that there are non-eosinophilic asthma phenotypes, that remodelling is independent of inflammation, and that steroids do not prevent children developing progressive airflow obstruction.	18701970
Airway structure	Altered Intercellular Communication	In young preschool children, the evidence for any eosinophilic airway inflammation is scant, the symptomatic benefit of inhaled steroids is meagre, and there is clear evidence that ICS do not modify the natural history.	18701970
Inflammation, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	About 24% of study participants had anaemia, which was associated with the presence and severity of chronic kidney disease, systemic inflammation, increased age, and reduced iron availability.	18702678
Airway structure, Asthma, Lung	Altered Intercellular Communication	Chronic airway inflammation in children with asthma might be present even in the absence of pathological lung function tests and is known to increase the risk of permanent pulmonary damage.	18702883
Craniosynostosis	Altered Intercellular Communication	Glycoconjugate expression of the sinus mucosa in CRS is markedly altered in extensive inflammatory conditions.	18702896
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Exploring the usefulness of inflammation-sensitive biomarkers to reveal potential sex differences in relation to low-grade inflammation in individuals with the metabolic syndrome.	18702947
Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Sex differences exist in the expression of different inflammation-sensitive biomarkers in relation to the metabolic syndrome (MetS).	18702947
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Quantitative fibrinogen, ESR, WBCC, as well as the absolute number of polymorphonuclear leukocytes are not sensitive enough to reveal the potential sex differences in relation to the various components of the MetS and the expression of the low-grade inflammation.	18702947
Inflammation	Altered Intercellular Communication	Myeloperoxidase activity and histological disease activity were assessed to quantify the ileal inflammation.	18704594
Inflammation, Adipose tissue loss, Cessation of life, Lipolysis, Cachexia	Altered Intercellular Communication	Lipolysis--not inflammation, cell death, or lipogenesis--is involved in adipose tissue loss in cancer cachexia.	18704987
Cessation of life, Inflammation, Cachexia	Altered Intercellular Communication	Cancer cachexia is an important, negative prognostic marker that has been linked to systemic inflammation and cell death through unclear mechanisms.	18704987
Inflammation, Lipolysis, Cachexia	Altered Intercellular Communication	Systemic inflammation (increased circulating levels of interleukin 6 [IL-6]) and enhanced lipolysis were confirmed in the cachectic patients compared with the other patients.	18704987
Inflammation, Secondary cholangitis, Obstruction of biliary tree	Altered Intercellular Communication	Implication of adhesion molecules in inflammation of the common bile duct in patients with secondary cholangitis due to biliary obstruction.	18705278
Inflammation	Altered Intercellular Communication	There are some other inflammatory markers such as complements (C) and immunoglobulins (Ig), which are involved in the pathogenesis of inflammation.	18705329
Inflammation, Carcinogenesis, Stomach Carcinoma	Altered Intercellular Communication	Although the mechanism of the relationship between gastric carcinoma and GCPs is obscure, we speculate that repeated erosion and regeneration induced by chronic inflammation causes multicentric carcinogenesis as well as an aberration of the gastric glands.	18705349
Mixed Salivary Gland Tumor, Carcinoma	Altered Intercellular Communication	The pathology involved were pleomorphic adenoma 9 (45%) cases, Kimura disease 2 (10%) cases, carcinoma 5 (25%) cases and inflammatory condition 4 (20%) cases.	18705472
Inflammation	Altered Intercellular Communication	Inflammation and degenerative histologic changes in cell structure because of age may predispose patients to a higher susceptibility.	18705546
Inflammation, Restenosis	Altered Intercellular Communication	It is known that inflammation plays a crucial role in restenosis.	18705636
Inflammation, B-Cell Lymphomas	Altered Intercellular Communication	And presence of immunoglobulin heavy chain gene rearrangement suggests the possibility of B-cell lymphoma arising in a background of IgG4-related chronic inflammation.	18705764
Inflammation, Colonic Diverticulitis, Kidney Diseases	Altered Intercellular Communication	Inflammation resulting from kidney disease may place patients with colonic diverticulitis at higher risk for developing renocolic or cutaneous renocolic fistulas.	18706151
Inflammation, Fibrosis Assessment, Edema, Neoplasms	Altered Intercellular Communication	Histology of the resected tissue revealed respiratory epithelial-lined stromal tissue with chronic inflammation, edema and fibrosis, but no tumor cells.	18706226
ARCN1 gene, Inflammation	Altered Intercellular Communication	We hypothesised that intraepithelial T-cells play a role in the response to lung irritants and that the T-cell populations would be altered and associated with signs of inflammation in COPD.	18706796
Airway structure, Bronchitis	Altered Intercellular Communication	Airway inflammation was recorded visually using bronchitis index (BI).	18706796
Unspecified visual loss, Complication Aspects, Behcet Syndrome, Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation in Behcet disease: incidence of ocular complications and of loss of visual acuity.	18708181
Inflammatory abnormality of the eye	Altered Intercellular Communication	A total of 168 consecutive patients with BD-associated ocular inflammation treated at five academic center ocular inflammation subspecialty practices were included.	18708181
Inflammation, Complication Aspects	Altered Intercellular Communication	Main outcome measures included VA, structural ocular complications of inflammation, and intraocular pressure (IOP).	18708181
Inflammatory abnormality of the eye	Altered Intercellular Communication	In a time-dependent analysis, current activity of ocular inflammation was associated with an increased risk of loss of VA to 20/50 or worse (relative risk [RR], 2.45; 95% confidence interval [CI], 1.1 to 5.5; P = .03) and to 20/200 or worse (RR, 2.67; 95% CI, 1.2 to 5.8; P = .01).	18708181
Complication Aspects, Inflammatory abnormality of the eye	Altered Intercellular Communication	Loss of VA and occurrence of ocular complications were common in patients with ocular inflammation associated with BD, even with aggressive therapy.	18708181
Inflammation, Ocular Hypotension	Altered Intercellular Communication	Ongoing inflammation during follow-up, presence or occurrence of posterior synechiae, hypotony, and elevated IOP were associated with an increased risk of loss of VA.	18708181
Tissue damage, Inflammation	Altered Intercellular Communication	Inflammation and tissue damage may be key pathogenetic pathways and we hypothesized that 1-lung ventilation may induce an inflammatory cascade reflected by markers for such a response.	18708192
Proteinuria, Inflammation, Hyperlipidemia, Diabetes Mellitus, Anemia, Obesity, Hypertension, CTCAE, Chronic Kidney Diseases	Altered Intercellular Communication	The risk factors for CKD include diabetes, hypertension, smoking, systemic inflammation, obesity, proteinuria, dislipidaemia and anaemia, as well as gender, age, ethnic minority status and positive family history.	18709007
Inflammation, Leukocytosis, Fever, CTCAE, Pustulosis of Palms and Soles	Altered Intercellular Communication	Acute generalized exanthematous pustulosis is a rare, sterile inflammation of the skin (and mucous membranes) characterized by acute onset of generalized pustule formation, fever and leukocytosis, and a rapid resolution.	18709306
Pancreatic Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	While the proteomic analysis of serum was capable of screening individuals for pancreatic disease (i.e., CP and Ca vs. H), specific urine biomarkers further distinguished malignancy (Ca) from chronic inflammation (CP).	18709425
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	Salivary resistin reflects local inflammation in Sjogren's syndrome.	18709689
Sjogrens Syndrome", Inflammation, PEELING SKIN SYNDROME	Altered Intercellular Communication	To assess the role of resistin in primary Sjogren's syndrome (pSS) and its relation to local inflammation.	18709689
Inflammation, PEELING SKIN SYNDROME	Altered Intercellular Communication	Resistin levels in saliva were related to the intensity of inflammation in the minor salivary glands of pSS patients.	18709689
Inflammation, PEELING SKIN SYNDROME	Altered Intercellular Communication	We suggest that resistin is expressed in the salivary glands of patients with pSS and may be a driving factor of local inflammation.	18709689
Pain Distress Question, Neurogenic Inflammation	Altered Intercellular Communication	Some hypothesis exist and we think it might negatively affect the neurogenic inflammation that surely acts in pain maintaining.	18710060
Inflammation, Malabsorption Syndrome	Altered Intercellular Communication	Small bowel mucosal morphology and inflammation, symptoms, coeliac serology and malabsorption laboratory data were evaluated at baseline and at the end of the study.	18710436
Inflammation, Malnutrition, Cardiovascular Diseases	Altered Intercellular Communication	Chronic inflammation is the cause of malnutrition and cardiovascular disease in hemodialysis patients.	18711296
Inflammation, Guillain-Barre Syndrome, Familial	Altered Intercellular Communication	Elevated alphaBC-IgG indices might therefore serve as markers of PNS inflammation and supplement currently used laboratory tests in the diagnosis of GBS.	18712293
Acute inflammation, Nutritional	Altered Intercellular Communication	Gln supplementation significantly attenuated postoperative inflammation and ameliorated postoperative immunodepression as well as nutritional depression in GI surgery.	18712409
Inflammation, diabetic	Altered Intercellular Communication	In healthy as well as in diabetic patients, MALP-2 induced local inflammation that faded after 48 h. The effectiveness of MALP-2 in the healing of chronic wounds in humans, e.g.	18713273
Inflammation, Scleroderma	Altered Intercellular Communication	Usually the disease begins in childhood or adolescence on the trunk or limbs, with no preceding inflammation or subsequent sclerodermatous changes.	18713593
Asthma, Pneumonitis	Altered Intercellular Communication	As adults, these mice showed enhanced airway hyperreactivity, chronic pulmonary inflammation, and diffuse emphysematous-type lesions in the lungs.	18714021
Inflammation, Atherosclerosis	Altered Intercellular Communication	C-reactive protein (CRP), a marker of systemic inflammation, is associated with risk of coronary events and sub-clinical measures of atherosclerosis.	18714381
Hormone abnormality, Malignant neoplasm of breast	Altered Intercellular Communication	Hormonal disorders in childhood and puberty symptoms of early menarche play a crucial role in increasing the risk of malignant breast neoplasms.	18714573
Inflammation, Acute cerebrovascular disease	Altered Intercellular Communication	Accumulating evidence suggests that inflammation plays an important role in the development of acute cerebrovascular disease.	18715563
Neurogenic Inflammation, Infection	Altered Intercellular Communication	It is debated whether chronic urogenital inflammations and infections may trigger the formation of antisperm antibodies (ASA) in semen.	18715698
Inflammation, Thrombosis, Edema, Abruptio Placentae	Altered Intercellular Communication	There was also some interstitial edema and inflammation at the base of the lingua, in addition to a chorionic villus thrombosis and abruptio placentae.	18715891
Inflammation, Fever, CTCAE, Ulcer	Altered Intercellular Communication	The case of a 78-year-old woman with high fever and severe inflammation caused by iliopsoas abscess secondary to a sacral pressure ulcer is reported.	18716341
allergic inflammation	Altered Intercellular Communication	These results may indicate the absence of a correlation between clinical status and quality of life and levels of ECP in tissues with allergic inflammation.	18716399
Inflammation	Altered Intercellular Communication	With the aid of orbital imaging, a diagnosis of orbital apex inflammation secondary to HZO was confirmed, and he was treated with intravenous acyclovir and oral steroids.	18716975
Inflammation, Peritonitis	Altered Intercellular Communication	We suggest that chronic inflammation or subclinical peritonitis is a predisposing factor for this complication.	18717287
Cataract, Inflammation	Altered Intercellular Communication	Sequestration of bacteria within the capsular fornices after cataract extraction with intraocular lens implantation can cause both acute and chronic inflammation.	18717441
Inflammation	Altered Intercellular Communication	Inflammation persisted despite several vitreous taps and the injection of intravitreal antibiotics.	18717441
Inflammation, Asthma, Hypersensitivity	Altered Intercellular Communication	We present a case of a 41-year-old male laborer who developed hypo- and hyperpigmented areas on his hands, without signs of inflammation or allergic reaction, together with several episodes of bronchial asthma, after occupational handling of sooty mold-covered citrus fruit.	18717611
Inflammation, Psoriasis, Dermatologic disorders, Disease	Altered Intercellular Communication	Psoriasis is a common dermatological disorder characterized by an immune-mediated chronic inflammation which is associated with a variety of other diseases commonly referred to as comorbidities.	18717681
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Previous studies have reported the presence of low-grade inflammation in Alzheimer disease (AD).	18717723
Inflammation, atherosclerotic, Chronic disease	Altered Intercellular Communication	Plasma activity of the platelet-activating factor acetylhydrolase (PAF-AH) plays an important role in inflammation and atherosclerotic process in chronic diseases.	18718550
Inflammation, Cachexia, Anorexia	Altered Intercellular Communication	Anorexia, inflammation, insulin resistance and increased muscle protein breakdown are frequently associated with cachexia.	18718696
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Diffuse nonspecific chronic inflammation with fibrosis was present in all specimens (100%).	18718788
Inflammation, Neoplasms	Altered Intercellular Communication	The lobulated, paucicellular myxoid tumor showed prominent vascularity, stromal inflammation, including neutrophils, and immunopositivity for CD34, vimentin, and muscle-specific actin.	18718794
Crohn Disease, Inflammation	Altered Intercellular Communication	There was marked and sustained improvement in Crohn's disease symptoms with the Harvey-Bradshaw index falling from 13 to 3, in serum markers of inflammation (C-reactive protein fell from 79 to 2) and endoscopic appearance.	18719139
Sepsis, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	SIRS and sepsis are associated with stressful inflammatory conditions.	18719339
Inflammation, Anemia, Obesity, Chronic disease	Altered Intercellular Communication	Obesity is characterized by chronic, low-grade, systemic inflammation, which, in turn, has been associated with anemia of chronic disease.	18719644
Overweight and obesity, Inflammation	Altered Intercellular Communication	Overweight and obesity were associated with changes in serum iron, TS, and ferritin that would be expected to occur in the setting of chronic, systemic inflammation.	18719644
Hemorrhagic Disorders, Deglutition Disorders, Inflammation, Traumatic injury	Altered Intercellular Communication	It occurs with no underlying medical condition such as trauma, hemorrhagic diathesis, or medically induced anticoagulation.We report a case of a 48-year-old man who presented with progressive dysphagia, signs of inflammation, and a reduced general health status.	18719865
Sensorineural Hearing Loss (disorder)	Altered Intercellular Communication	Imaging analysis in cases with inflammation-induced sensorineural hearing loss.	18720058
Disturbance, Sensorineural Hearing Loss (disorder)	Altered Intercellular Communication	3D-FLAIR imaging is sensitive to inflammatory inner ear disturbances and may be a useful method in investigating the severity of inner ear disturbance in cases of inflammation-induced SNHL.	18720058
Granulomatosis with polyangiitis, Sensorineural Hearing Loss (disorder), Acute otitis media, Meningitis	Altered Intercellular Communication	Five cases with inflammation-induced acute SNHL by different conditions are included in this study: acute meningitis, acute otitis media, and Wegener granulomatosis.	18720058
Inflammation, Critical Illness	Altered Intercellular Communication	Chromogranin A (CGA), a stress marker released with catecholamines by the adrenal medulla, has never been associated with acute inflammation in critically ill patients.	18720287
Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	To determine evidence for a link between serum concentration of CGA, biomarkers of inflammation, and outcome inpatients admitted with or without the systemic inflammatory response syndrome (SIRS).	18720287
Inflammation	Altered Intercellular Communication	Computerised tomography findings pointed to purulent inflammation of the frontal and part of the ethmoid sinuses, with a defect of the anterior wall of the right frontal sinus.	18720750
Inflammation	Altered Intercellular Communication	Having analysed the anamnestic data, radiography and laboratory results, and intraoperative findings, we were not able to conclude decisively whether it was a complication of acute or chronic inflammation.	18720750
Inflammation	Altered Intercellular Communication	Functionally, the majority of the identified pathways are involved in the regulation of inflammation, proliferation, cell survival, and angiogenesis.	18721452
Shock, Inflammation	Altered Intercellular Communication	Heat shock protein (HSP) 60 is induced by a variety of stressors, including oxidative stress and inflammation, and it plays a protective role against stress-induced cardiomyocyte injury.	18721521
Communicable Diseases	Altered Intercellular Communication	A stromal infiltrate with an overlying area of epithelial defect can be challenging to differentiate between infectious and noninfectious inflammatory conditions.	18722962
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	The risk for cardiovascular events is related to the composition and stability of an atherosclerotic plaque driven by inflammation and deposition of lipids.	18723424
Sepsis, Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Sepsis is an archetypal condition with molecular links between inflammation and coagulation.	18723433
ARCN1 gene, Chronic Obstructive Airway Disease, Exacerbation, Airway structure	Altered Intercellular Communication	Frequent chronic obstructive pulmonary disease (COPD) exacerbations are a major cause of hospital admission and mortality and are associated with increased airway inflammation.	18723437
Inflammation	Altered Intercellular Communication	Silencing of Abcd1 and Abcd2 genes sensitizes astrocytes for inflammation: implication for X-adrenoleukodystrophy.	18723473
Refractory anemias, Cardiovascular morbidity, vascular inflammations	Altered Intercellular Communication	The results underline the sustained downregulation of MIF as a potential new mechanism by which anti-TNF therapy might reduce vascular inflammation, and as such perhaps cardiovascular morbidity in RA patients.	18723565
Benign Prostatic Hyperplasia, Inflammation	Altered Intercellular Communication	The presence of these cells may also be influenced by spontaneous chronic inflammation or nodular prostate hyperplasia in men.	18724530
Inflammation, Injury of breast	Altered Intercellular Communication	However, between the 2nd and 3rd vaccination she suffered a breast injury with local inflammation.	18725327
Intraocular inflammation	Altered Intercellular Communication	0.5% prednisolone acetate appeared to be significantly more effective as vehicle in controlling intraocular inflammation after phacoemulsification; both groups had a similar safety profile.	18726610
Inflammation, diabetic, macroangiopathy	Altered Intercellular Communication	Monocyte nitrosylated protein expression is a new biomarker of metabolic control and inflammation in diabetic subjects with macroangiopathy.	18726872
Pain Distress Question, Erythema, Swelling, Inflammation	Altered Intercellular Communication	Reactions characterized by pain, swelling, redness, or inflammation have been experienced by patients who self-inject glatiramer acetate, interferon beta-1b, or interferon beta-1a.	18727339
Inflammation, Asthma, Inflammatory disorder	Altered Intercellular Communication	Asthma is an inflammatory disease, yet clinical tools that evaluate asthma control do not include measures of inflammation.	18727466
Inflammation, Pelvic Inflammatory Disease	Altered Intercellular Communication	Fitz-Hugh-Curtis (FHC) syndrome is inflammation of the liver capsule associated with pelvic inflammatory disease.	18728379
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Bronchoscopic biopsy showed chronic granulomatous inflammation in 16 patients.	18729304
Inflammation, Aortic Aneurysm, Abdominal, Aneurysm	Altered Intercellular Communication	In vivo imaging of abdominal aortic aneurysms: increased FDG uptake suggests inflammation in the aneurysm wall.	18729562
Aneurysm	Altered Intercellular Communication	To study the potential of integrated positron emission tomography and computed tomography (PET/CT) to identify aneurysm wall inflammation.	18729562
Inflammation, Aneurysm	Altered Intercellular Communication	FDG-PET/CT is a promising technique to identify inflammation of the aneurysm wall.	18729562
Hormone abnormality, Calcinosis	Altered Intercellular Communication	The presence of ectopic calcification could not be explained by a systemic hormonal abnormality.	18729813
Chorioretinitis, Inflammatory abnormality of the eye	Altered Intercellular Communication	Two patients with ocular inflammation of unknown origin developed severe chorioretinitis after IVTA injection.	18751717
Icterus, Inflammation, Drug-Induced Liver Disease, Cholestasis	Altered Intercellular Communication	We report a case of a young male who developed jaundice associated with cefdinir use with pathological confirmation of moderate cholestasis with portal and lobular mixed inflammation and focal bile duct injury consistent with drug-induced liver injury.	18752027
Inflammation, Carcinogenesis, Primary malignant neoplasm	Altered Intercellular Communication	The proposed role of chronic inflammation in prostate carcinogenesis has prompted investigation into the association of common genetic variation in TLRs with the risk of this cancer.	18752252
Inflammation	Altered Intercellular Communication	Immune response to H. pylori HSP60 indicates chronic inflammation in the antrum (p=0.003).	18754320
Involuntary Movements, Autonomic nervous system disorders	Altered Intercellular Communication	Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare inborn error of neurotransmitter biosynthesis that leads to a combined deficiency of catecholamines and serotonin and is characterized by global developmental delay, involuntary movements, and autonomic dysfunction.	18754761
Inflammation, Calcinosis	Altered Intercellular Communication	Histological analysis of the pericardium showed dense collageneous matrix, mild chronic inflammation and calcification.	18754936
Inflammation, Carpal instability	Altered Intercellular Communication	We report a 43-year-old man who presented with features of acute wrist inflammation with scapholunate dissociation.	18756333
Inflammation	Altered Intercellular Communication	Histological evaluation established the diagnosis of epidermal inclusion cyst with mild nonspecific inflammation.	18756336
Inflammation, Periodontitis, metabolic disturbance	Altered Intercellular Communication	Inflammation led to metabolic disturbances and antioxidative defense system imbalance in patients with periodontitis.	18756728
Inflammation, Ulcer	Altered Intercellular Communication	The ulcers were sharply demarcated,without remarkable inflammation around or between the ulcers.	18756986
Inflammation, Granuloma, Eosinophilic inflammation, Inflammatory, Ulceration, CTCAE	Altered Intercellular Communication	Histopathological findings were mostly unspecific, such as chronic inflammation, active inflammation, ulceration, eosinophil infiltration, inflammatory granulation, granuloma, and thickness of vessel wall.	18756986
Carpal Tunnel Syndrome	Altered Intercellular Communication	Potential pathophysiologic roles of hormonal manipulation with AIs and other risk factors that might contribute to CTS are discussed.	18757265
Inflammation, Bacterial Infections	Altered Intercellular Communication	To prevent the deterioration of BCHL, the control of eosinophilic inflammation and bacterial infection is mandatory.	18758390
Inflammation, hepcidin	Altered Intercellular Communication	Hepcidin, an antimicrobial peptide, is a key regulator of iron metabolism and synthesis of hepcidin is regulated by iron status and inflammation.	18758412
Inflammation, Anemia, hepcidin	Altered Intercellular Communication	In EPO resistant anemia, multiple factors, including iron and inflammation related conditions, are likely to affect the level of hepcidin and this may explain the lack of elevated serum hepcidin in this condition.	18758412
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	In addition, presence of inflammation associated with breast malignancies had a significant correlation with VEGF positive staining.	18758633
Inflammation, Structure of papillary muscle	Altered Intercellular Communication	Transplacental passage of maternal anti-SSA antibody could account for the fetal inflammation at the ruptured chordae and the papillary muscle.	18758812
Inflammation, Injury of liver	Altered Intercellular Communication	Hsp70 correlates with markers of heart function and hepatic injury, but not with signs of inflammation.	18759004
Inflammation	Altered Intercellular Communication	Since the patient had a gynaecological history of widespread inflammation, she was referred for transabdominal operative ureterolysis combined with hysterectomy and adnexectomy.	18759151
Inflammation, Diverticular Diseases	Altered Intercellular Communication	The pathogenesis of symptoms of uncomplicated diverticular disease (UDD) is unclear, but changes in gut microflora and physiologic inflammation may be implicated.	18759154
Inflammation, Enthesitis	Altered Intercellular Communication	Distinct topography of erosion and new bone formation in achilles tendon enthesitis: implications for understanding the link between inflammation and bone formation in spondylarthritis.	18759270
Refractory anemias, Rheumatoid Arthritis, Inflammation, Synovitis	Altered Intercellular Communication	The serum C-reactive protein (CRP) concentration is commonly used in rheumatoid arthritis (RA) as a surrogate marker of systemic inflammation, presumably induced by synovitis.	18759279
Refractory anemias, Inflammation, Disease, Obesity	Altered Intercellular Communication	Adiposity is independently associated with CRP levels in women with RA, and thus may confound the estimation of RA disease activity when serum CRP concentration is used as a surrogate for systemic inflammation.	18759279
Inflammation, Arthritis, Hypoxia	Altered Intercellular Communication	Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis.	18759291
Inflammation, Arthritis, Hypoxia	Altered Intercellular Communication	This study was thus undertaken to investigate the hypothesis that extracellular HMGB-1 may be a coupling factor between hypoxia and inflammation in arthritis.	18759291
Sample Size Calculation	Altered Intercellular Communication	Considering their role as important mediators of intercellular communication, microparticles could be a novel link between activated cellular compartments in the pathogenesis of SSc.	18759303
Cardiovascular morbidity, Inflammation	Altered Intercellular Communication	Increased concentrations of N-terminal pro-brain natriuretic peptide (NT-proBNP) are associated with cardiovascular morbidity and mortality, but little is known about their relationship to chronic inflammation.	18759301
Inflammation, Refractory anemias, Coronary Arteriosclerosis, Rheumatoid Arthritis, Arterial Stiffness	Altered Intercellular Communication	Patients with rheumatoid arthritis (RA) have chronic inflammation, increased arterial stiffness, and accelerated coronary atherosclerosis.	18759301
Refractory anemias, Inflammation, Calcification of coronary artery	Altered Intercellular Communication	This study was undertaken to test the hypothesis that NT-proBNP concentrations are elevated in patients with RA and are associated with coronary artery calcification and markers of inflammation.	18759301
Inflammation, Tuberculosis	Altered Intercellular Communication	Comparative statistics of tuberculous fistula-in-ano with fistulas due to specific inflammation revealed no major differences.	18760061
Tears body substance, Inflammation, Pathology, Rheumatism	Altered Intercellular Communication	Because tendons tears and thicknesses are associated with inflammation, awareness of tendon pathologies is very important in rheumatic diseases.	18760201
Inflammation, Cholecystitis	Altered Intercellular Communication	There is a negative association between BMI and the inflammation severity of cholecystitis in males, which resulted in a higher incidence of severe cholecystitis in the nonobese male patients.	18760398
methyldopa, Inflammation, Dyslipidemias, Endothelial dysfunction	Altered Intercellular Communication	This finding may suggest that pathogenic processes linking to wider venular caliber be shared by early AMD and common cardiovascular risk factors such as inflammation, dyslipidemia, and endothelial dysfunction.	18760764
Inflammation, Demyelination, Destructive procedure (surgical), Necrosis	Altered Intercellular Communication	Histology revealed inflammation with necrosis, demyelination and destruction of axons.	18760886
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a syndrome of chronic progressive airflow limitation as a result of chronic inflammation of the airways and lung parenchyma.	18761816
Inflammation, Vesico-Ureteral Reflux	Altered Intercellular Communication	Clinical and laboratory indices of inflammation were comparable in all groups, as was the incidence of vesicoureteric reflux.	18762516
Inflammation, Pelvic mass, Actinomycosis, Mass of urinary bladder	Altered Intercellular Communication	The MRI showed a heterogeneous pelvic mass and a bladder mass suggesting chronic inflammation caused by an organism such as actinomycosis.	18762960
Diabetes Mellitus, Insulin-Dependent, Pelvic Girdle Pain	Altered Intercellular Communication	Increased levels of relaxin, a hormone structurally belonging to the insulin-like growth factor family, has been associated with both pelvic girdle pain and type 1 diabetes in pregnancy.	18763174
Multiple Myeloma, Inflammation	Altered Intercellular Communication	Familial multiple myeloma associated with disorders of chronic inflammation: first report from Turkey.	18765313
Inflammation, Hereditary	Altered Intercellular Communication	This family enhances the role of hereditary factors and chronic inflammation in the etiology of MM.	18765313
Inflammation, Rupture, Necrosis, Cessation of life, Dental Plaque	Altered Intercellular Communication	Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is expressed abundantly in the necrotic core of coronary lesions, and products of its enzymatic activity may contribute to inflammation and cell death, rendering plaque vulnerable to rupture.	18765397
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Type I interferons might form the link between Toll-like receptor (TLR) 3/7 and TLR4-mediated synovial inflammation in rheumatoid arthritis (RA).	18765427
Refractory anemias, Inflammation, Infection	Altered Intercellular Communication	Toll-like receptors (TLR) probably play a role in synovial inflammation and may also contribute to the understanding of the role of infections in RA.	18765427
Respiratory Distress Syndrome, Adult, Communicable Diseases, Inflammation	Altered Intercellular Communication	In view of the fact that evaluation for infectious or noninfectious etiologies of ARDS was unrevealing, we reasoned that systemic inflammation in early subclinical PM may have precipitated alveolar-capillary membrane injury.	18766122
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Chronic inflammation in rheumatoid arthritis (RA) is associated with vascular endothelial dysfunction.	18766955
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The mechanisms by which inflammation may induce endothelial dysfunction are not fully understood.	18767412
Cytomegalovirus Retinitis, Immunocompromised Host, Vitreous inflammatory cells	Altered Intercellular Communication	Unlike CMV retinitis in immunocompromised patients, CMV retinitis in immunocompetent patients had significant anterior and vitreous inflammation but did not require antiviral treatment.	18767494
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is a hallmark of the development of atherosclerosis and is mediated by prostaglandins, catalyzed by cyclooxygenase (COX)-2.	18768181
Inflammation, Cardiac Death	Altered Intercellular Communication	The association of sudden cardiac death with inflammation and other traditional risk factors.	18769368
Kidney Failure, Chronic, Inflammation, Cardiac Death	Altered Intercellular Communication	Here, we sought to determine the frequency of sudden cardiac death and its association with inflammation and other risk factors among the CHOICE (Choices for Healthy Outcomes In Caring for ESRD) cohort of 1,041 incident dialysis patients.	18769368
Chronic kidney disease stage 5, Inflammation, Cardiac Death, Malnutrition	Altered Intercellular Communication	Hence, we found that sudden cardiac death is common among patients with end stage renal disease and that inflammation and malnutrition significantly increased its occurrence independent of traditional cardiovascular risk factors.	18769368
Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Endothelial inflammation with chemokine involvement contributes to acute coronary syndromes (ACS).	18769620
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Atorvastatin lowered endothelial ENA-78 production during inflammation typical of ACS.	18769620
Inflammation, Chronic heart failure, Endothelial dysfunction	Altered Intercellular Communication	[Inflammation and endothelial dysfunction in patients with chronic heart failure].	18769823
Inflammation, Congestive heart failure	Altered Intercellular Communication	To assess the association between inflammation and ED in CHF.	18769823
Inflammation, Fibrosis Assessment, Edema	Altered Intercellular Communication	The main morphological alterations included degenerative changes of portal bile ducts, portal edema, inflammation, and fibrosis as well as biliary interface activity and bilirubinostasis.	18769938
Inflammation	Altered Intercellular Communication	Based on the morphological observation, a possible disease-progression model starting with an initial damage of portal bile ducts (primary insult) with associated portal/periportal changes (inflammation, ductular reaction) and resulting in secondary parenchymal changes is proposed.	18769938
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	However, our data show evidence of increased systemic inflammation in patients with acute coronary syndrome, which was unrelated to an increased HP seropositivity.	18770033
Inflammation, Attachment (action), Rheumatoid Arthritis	Altered Intercellular Communication	Anti-TNF-alpha immunotherapy is associated with increased gingival inflammation without clinical attachment loss in subjects with rheumatoid arthritis.	18771364
Refractory anemias, Inflammation, Periodontitis	Altered Intercellular Communication	Inflammation and destruction constitute two interrelated yet separate components of periodontitis in patients with RA.	18771364
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	The association between periodontal inflammation and non-fatal stroke is still controversial and limited to evidence in Western countries.	18771365
Inflammation, Hemorrhage, Periodontal Infection, Porphyromonas gingivalis, Periodontal Diseases, Tooth structure	Altered Intercellular Communication	Chronic oral inflammatory burden was measured as 1) clinical periodontal infection categorized as no periodontal disease, periodontal disease (at least one tooth with > or =4 mm loss of attachment and bleeding on probing as an indicator of inflammation), or edentulism and 2) serum immunoglobulin G antibody response to Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinomycetemcomitans) and Porphyromonas gingivalis.	18771368
Inflammation, atherosclerotic	Altered Intercellular Communication	These data provide preliminary evidence that inflammation, potentially contributing to atherosclerotic processes, may underlie the association between high CRP and changes in attention-executive-psychomotor performance.	18771451
Chemosis of conjunctiva, Communicable Diseases, Inflammation	Altered Intercellular Communication	There were no cases of chemosis, infection, unexplained post-operative inflammation or delayed wound healing.	18771499
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Low-grade chronic inflammation is associated with risk for type 2 diabetes.	18771568
Inflammation	Altered Intercellular Communication	T cells play a major role during inflammation, but little is known about T cell subpopulations in the cerebrospinal fluid (CSF).	18771722
Inflammation, Chronic myeloproliferative disorder	Altered Intercellular Communication	Overall, the hypothesis of low degree inflammation in a subgroup of MPD is supported.	18771722
Claudication (finding), Inflammation, Ischemia	Altered Intercellular Communication	Decreased FMD may be caused by a decrease in arterial shear stress due to claudication and inflammation due to muscle ischemia and reperfusion.	18771886
Inflammation, FRONTOMETAPHYSEAL DYSPLASIA 1	Altered Intercellular Communication	We assumed that endovascular revascularization of lower limb arterial obstructions ameliorates FMD and lowers inflammation through improvement of peripheral perfusion.	18771886
Unspecified visual loss, Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	No severe vision loss due to ocular inflammation or uveitis occurred.	18772178
Inflammatory abnormality of the eye, Unspecified visual loss	Altered Intercellular Communication	CONCLUSIONS/APPLICATION TO CLINICAL PRACTICE: Same-day verteporfin and ranibizumab was safe and not associated with severe vision loss or severe ocular inflammation.	18772178
Inflammation	Altered Intercellular Communication	We compared the degree of systemic inflammation and its relation to the angiographic outcomes after drug-eluting stent (DES) implantations.	18772180
Vasculitis, Diabetic Neuropathies	Altered Intercellular Communication	There is evidence of vasculitic inflammation documented in diabetic neuropathy.	18772696
Chronic inflammation	Altered Intercellular Communication	Therefore we must view these variations as factors predisposing to more rapid and frequent appearance and persistence of chronic inflammations.	18773688
Inflammation, Atrophic	Altered Intercellular Communication	They were usually focal and associated with variable degrees of chronic inflammation and atrophy.	18773741
Spinal Cord Injuries, Dehydration	Altered Intercellular Communication	One case of spinal cord injury was treated with medicine for dehydration and anti-inflammation, and was restored to preoperative muscle power of inferior extremity after 6 months.	18773801
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	This relatively inexpensive marker of inflammation can aid in the risk stratification and prognosis of patients diagnosed with ACS.	18773982
Appendage, Inflammation	Altered Intercellular Communication	Epiploic appendagitis is a very rare condition that results from acute inflammation of an appendix epiploica.	18774058
Pneumonitis	Altered Intercellular Communication	A significant increase in the number of all LF cell phenotypes was observed in patients with pulmonary inflammation; the difference in both T- and B-lymphocytes was statistically significant (p=0.010).	18774236
Pain Distress Question, Inflammation	Altered Intercellular Communication	A set of conditions characterized particularly by pain, inflammation and/or autonomic reactivity has a higher incidence in people with MD.	18774423
Inflammation, Chronic Kidney Insufficiency, Fever, CTCAE, Leukocytosis, Edema, Hypertension, CTCAE	Altered Intercellular Communication	An 88-year-old woman with hypertension, chronic vein insufficiency, and repeated cellulites in the right lower extremity was admitted to our hospital with a new episode of right leg inflammation and edema associated with fever and leukocytosis.	18774688
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Phytoestrogens (including lignans and isoflavones) may enhance the management of diabetes and are hypothesized to act through inflammation pathways.	18775100
Inflammation, Calcinosis	Altered Intercellular Communication	It also results in a drop of fetuin-A concentration which is the calcification inhibitor negatively regulated by inflammation.	18775894
Inflammation, Adenoma, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation, adenoma and cancer: objective classification of colon biopsy specimens with gene expression signature.	18776587
Inflammation, Metabolic Syndrome X, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	We determined the degree to which metabolic syndrome components, inflammation and health behaviours account for the social gradient in CHD.	18777168
Celiac Disease, Gastrointestinal inflammation, Inflammatory Bowel Diseases	Altered Intercellular Communication	Although clinically different, celiac sprue and inflammatory bowel disease are characterized by chronic intestinal inflammation and associated extraintestinal manifestations.	18777226
Inflammation	Altered Intercellular Communication	In contrast, long-term illness was associated with inflammation, stimulus-response and immune functions.	18778695
Inflammation, Atherosclerosis	Altered Intercellular Communication	Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is a lipoprotein-bound enzyme that can release atherogenic isoprostanes from esterified phospholipids and that may be involved in inflammation and atherosclerosis.	18779277
AURKAIP1 gene, Inflammation	Altered Intercellular Communication	Although an overlap was present between the groups, the overall inflammation and number of plasma cells in and around the ampulla was significantly increased in AIP compared with CP and IDC.	18779730
Waldenstrom Macroglobulinemia	Altered Intercellular Communication	To be included as an area of sparing, both duct and acinar parenchyma had to be free of lymphoplasmacytic inflammation, and the focus had to be at least 0.5 cm in diameter.	18779731
Inflammation, Carcinogenesis, Prostate carcinoma	Altered Intercellular Communication	Inflammation has been implicated in prostate carcinogenesis; therefore, the use of nonsteroidal anti-inflammatory drugs (NSAIDs) has the potential of decreasing the risk of prostate cancer.	18780337
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Disrupting this line of chemokine-mediated intercellular communication may contribute to the pathogenesis of Alzheimer's disease (AD).	18780969
Inflammation, Heart valve disease	Altered Intercellular Communication	There was an increase in TNF-alpha and IL-6 tissue immunoreactivity with the progression of heart valve disease from mild to advanced inflammation.	18781820
Inflammatory disease of mucous membrane	Altered Intercellular Communication	We examined nasal mucosa inflammation, the presence of nasal specific-IgE and the response to nasal allergen provocation test (NAPT) in patients with seasonal IR who presented symptoms only in spring.	18782115
Inflammation, Prostatic Intraepithelial Neoplasias	Altered Intercellular Communication	Factors predicting a surgical GS upgrade were a higher PSA level (P = 0.005), presence of perineural invasion (P = 0.043), absence of inflammation (P < 0.001), and absence of associated high-grade prostatic intraepithelial neoplasia (P = 0.02).	18782303
Inflammation, Fracture	Altered Intercellular Communication	The most common complications for titanium frameworks were resin or veneer fractures and soft tissue inflammation.	18783415
Inflammation, Depression, CTCAE	Altered Intercellular Communication	This study indicates an association between increased levels of plasma 8-iso-PGF2alpha and IL-6 with depressive symptomatology in elderly individuals and indicates the necessity for further investigation, possibly within the framework of an integrated involvement of oxidative damage and inflammation in the pathophysiology of depression in the elderly.	18783834
Choroidal Neovascularization, Choroiditis	Altered Intercellular Communication	Multifocal choroiditis (MFC) is an inflammatory condition, occasionally associated with choroidal neovascularization (CNV).	18784620
Kidney Diseases, Nephritis	Altered Intercellular Communication	Reduction of the vitamin D hormonal system in kidney disease is associated with increased renal inflammation.	18784644
Inflammation, Chronic Kidney Diseases, Kidney Diseases	Altered Intercellular Communication	To examine any potential role for 1,25-dihydroxyvitamin D (1,25(OH)2D) in inflammation associated with chronic kidney disease we measured vitamin D metabolites, markers of inflammation and gene expression in 174 patients with a variety of kidney diseases.	18784644
Nephritis	Altered Intercellular Communication	Logistic regression analysis with urinary MCP-1 as binary outcome showed that a 10-unit increase in serum 1,25(OH)2D or 25OHD resulted in lower renal inflammation.	18784644
Damage, Acute inflammation, Chronic disease	Altered Intercellular Communication	Patients with acute renal inflammation had a significant increase in urinary and tissue MCP-1, macrophage infiltration, and macrophage and renal epithelial CYP27B1 expression but significantly lower levels of serum 1,25(OH)2D in comparison to patients with chronic ischemic disease despite similar levels of renal damage.	18784644
Nephritis	Altered Intercellular Communication	Our study indicates that renal inflammation is associated with decreased serum vitamin D metabolites and involves activation of the paracrine/autocrine vitamin D system.	18784644
Kidney Diseases, Nephritis	Altered Intercellular Communication	Reduction of the vitamin D hormonal system in kidney disease is associated with increased renal inflammation.	18784644
Blepharitis, Pain Distress Question, Hemorrhage	Altered Intercellular Communication	Complications included pain in three cases, eyelid inflammation in four cases and severe bleeding in one case.	18784907
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Calgranulin A is reported to be mainly associated with acute inflammation while calgranulin B seems to play a role in chronic inflammatory disorders.	18784990
Refractory anemias, Inflammation	Altered Intercellular Communication	However, it is probably modest due to the marked inflammation in RA, in which mDC are dominant.	18785315
Inflammation	Altered Intercellular Communication	Our findings suggest that inflammation activates granzyme B, which participates in the destruction of RA-affected joints.	18785318
Granulomatous inflammation, Caseous necrosis	Altered Intercellular Communication	These diagnoses were verified by granulomatous inflammation with or without caseous necrosis on histology and tubercle bacilli were cultured in four cases.	18785421
CDISC SDTM Immunogenicity Specimen Assessments Test Name Terminology, Inflammatory abnormality of the eye	Altered Intercellular Communication	Patients presenting with ocular inflammations that failed to respond adequately to steroids alone after monotherapy for a mean period of 9 +/- 2 months (internal control) were offered the option to switch to a combined IST.	18785963
Inflammation, Infectious Lung Disorder	Altered Intercellular Communication	To measure lung function in infants with CF diagnosed by newborn screening and describe its association with pulmonary infection and inflammation.	18787217
Inflammation, Infectious Lung Disorder	Altered Intercellular Communication	Forty-eight hours later, infants with CF had bronchoalveolar lavage (BAL) for assessment of pulmonary infection and inflammation.	18787217
Inflammation, Infectious Lung Disorder	Altered Intercellular Communication	Pulmonary infection and inflammation in BAL samples did not explain the lung function results.	18787217
Multiple Organ Failure, Inflammation, Gastroenteritis, Seizures, Hepatotoxicity, Dermatitis, Dyspnea, Cardiac Arrhythmia	Altered Intercellular Communication	Each case was placed into one of the expected toxidromes: anticholinergic, mucosal inflammation, gastroenteritis, acute multisystem organ failure, delayed multisystem organ failure, cholinergic, cardiac dysrhythmia, hepatotoxicity, dermatitis, seizures, and dyspnea.	18788001
Granulomatous inflammation	Altered Intercellular Communication	Cultures for mycobacterium were negative and repeat TBB specimens revealed granulomatous inflammation.	18788440
Inflammation, Ventricular hypertrophy, Fibrosis Assessment, Coronary Arteriosclerosis, Infarction, Cardiomegaly	Altered Intercellular Communication	Hearts were examined for the presence of cardiomegaly, ventricular hypertrophy, coronary artery atherosclerosis, acute infarction, fibrosis, and inflammation.	18788850
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	[Comparative dynamics of markers of inflammation and NT-proBNP in different variants of treatment of patients with ACS].	18789006
Inflammation	Altered Intercellular Communication	Initial level of markers of inflammation (Il-6, CRP) in STEACS was lower than in NSTEACS.	18789006
Pancreatitis	Altered Intercellular Communication	Interleukin-1beta is a proinflammatory cytokine involved in pancreatic inflammation.	18789941
Sepsis, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The vascular growth factor angiopoietin 2 (Ang-2) is known to promote inflammation and endothelial dysfunction, but its prognostic capacity and relationship to outcomes in human sepsis are unknown.	18791490
Sepsis, Dysequilibrium, Observation Method - Coagulation	Altered Intercellular Communication	Pneumococcal purpura fulminans successfully treated with activated protein C. Evidence suggests that sepsis is a systemic inflammatory condition complicated by dysequilibrium in coagulation and fibrinolytic homeostasis, with a shift in the balance towards increased coagulation over fibrinolysis.	18791506
Destruction of tissue, Sarcoidosis, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Sarcoidosis is a systemic disease of unknown etiology that is characterized by chronic non-caseating granulomatous inflammation with tissue destruction.	18791743
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Despite evidence suggesting that B cells and the production of autoantibodies may play a significant role in IBD pathogenesis, the role of B cells in gut inflammation has not yet been thoroughly investigated.	18792412
Inflammation	Altered Intercellular Communication	On the other hand, ageing itself is associated with a mild degree of chronic inflammation.	18792481
Communicable Diseases, Inflammation	Altered Intercellular Communication	Besides, asymptomatic infectious and non-infectious inflammation is frequent in old age.	18792481
Inflammation	Altered Intercellular Communication	The levels of nitric oxide metabolites in elderly, clinically healthy individuals may be increased due to inflammation (Tab.	18792481
Leydig Cell Tumor, Inflammation, Epithelial cyst, Unilocular cyst, Neoplasms, Sarcoidosis, Fibrosis Assessment, Strawberry nevus of skin, Malignant Neoplasms, Adenomatoid Tumor	Altered Intercellular Communication	The lesions could be categorized as inflammatory (three hyalinized fibrosis, two sarcoidosis, one chronic inflammation), cystic (one epidermoid cyst, one unilocular cyst), benign neoplasms (two adenomatoid tumours, one Leydig cell tumour, one capillary haemangioma) or malignant neoplasms (one lymphoma).	18793303
Inflammation	Altered Intercellular Communication	This study has demonstrated that mixed C. albicans and C. glabrata biofilms may play an important role in the pathogenesis associated with severe inflammation in denture wearers.	18793360
Inflammation, Tubular atrophy, Chronic rejection of renal transplant, Renal glomerular disease	Altered Intercellular Communication	Crea and 1/Crea correlated best to CADI, chronic allograft nephropathy, chronic inflammation, tubular atrophy, vascular changes and glomerulopathy.	18793544
Inflammation, Tubular atrophy	Altered Intercellular Communication	Significant Tau correlation was found between CyC, 1/CyC and Larsson with CADI, chronic inflammation, tubular atrophy and chronic vascular changes.	18793544
MTA2 gene, Inflammation	Altered Intercellular Communication	(2) To determine if adolescents admitted for PID after the guideline change needed longer hospital stays and/or were more likely to be "very ill" [as measured by inflammation markers, e.g.	18794025
Pseudocyst, Inflammation, Microabscess, Recurrent skin infections	Altered Intercellular Communication	Suppurative inflammation with microabscess and pseudocyst formation is a characteristic histologic manifestation of cutaneous infections with rapid-growing Mycobacterium species.	18794042
Inflammation, Immunocompromised Host, Infection	Altered Intercellular Communication	We have observed a suppurative pattern of inflammation associated with infections by rapid-growing Mycobacterium species in immunocompromised patients.	18794042
Granulomatous inflammation	Altered Intercellular Communication	We report 6 cases in skin and soft tissue with an unusual but consistent lack of a predominance of granulomatous inflammation.	18794042
Suppuration, Inflammation, Granulomatous inflammation	Altered Intercellular Communication	Of the 6 cases, 4 had predominantly (approximately 75%) suppurative inflammation, 1 case predominantly demonstrated (approximately 75%) a mix of acute and chronic inflammation, and 1 case showed an approximately equal contribution of suppurative and granulomatous inflammation.	18794042
Inflammation	Altered Intercellular Communication	This could improve prognostication and allow for intervention strategies to reduce tumor-associated inflammation.	18794066
ARCN1 gene, Inflammation	Altered Intercellular Communication	This study supports previous findings of both, increased local and systemic inflammation in acute exacerbation of COPD.	18795228
Inflammation, Airway Obstruction	Altered Intercellular Communication	In virus-associated exacerbations, IL-6 is significantly increased and negatively correlated to FEV1 indicating a relation between virus-induced inflammation and airway obstruction.	18795228
Inflammation, Ovarian Failure, Premature	Altered Intercellular Communication	Xanthogranulomatous inflammation: a rare cause of premature ovarian failure.	18795307
Inflammation, Ovarian Failure, Premature	Altered Intercellular Communication	We report an unusual presentation of xanthogranulomatous inflammation of the genital tract in a young female presenting with premature ovarian failure.	18795307
Xanthogranulomatous inflammation, Chocolate cyst of ovary	Altered Intercellular Communication	The final histopathological report was suggestive of endometrioma with xanthogranulomatous inflammation involving adjacent ovary and fallopian tube.	18795307
Inflammation, Hepatobiliary Disorder, FAM126A gene	Altered Intercellular Communication	The survival rate of early HCC after hepatic resection is favorable, however, recurrence is considerably frequent and it depends on the degree of inflammation of underling liver disease.	18795705
Inflammation, FAM126A gene	Altered Intercellular Communication	Therefore, the control of inflammation of liver parenchyma and the preservation of liver function may be most important in patients with early HCC.	18795705
Inflammation, Fatty degeneration	Altered Intercellular Communication	Differences in reference to histological steatosis grade and inflammation were not significant.	18795706
Inflammation, Hemorrhage, Paronychia	Altered Intercellular Communication	Most (nine) of the patient's fingernails had alterations in colour, affecting more than half of the nail plate, and all the toenails had severe inflammation of the nail folds, haemorrhagic paronychia and subungual or intraungual haemorrhage.	18795937
Inflammation, Diabetes Mellitus, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Elevated ferritin concentrations frequently cluster with well-established risk factors of diabetes including obesity, metabolic syndrome, chronic inflammation, and altered circulating adipokines.	18796516
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	We aimed to investigate, in a middle-aged and elderly Chinese population, whether elevated ferritin concentrations are associated with higher risk of metabolic syndrome and type 2 diabetes and to what extent the associations were influenced by obesity, inflammation, and adipokines.	18796516
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Elevated circulating ferritin concentrations were associated with higher risk of type 2 diabetes and metabolic syndrome in middle-aged and elderly Chinese independent of obesity, inflammation, adipokines, and other risk factors.	18796516
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Pathogen burden and inflammation do not seem to be related to insulin resistance, metabolic syndrome, or IFG in this population.	18796618
Premenstrual	Altered Intercellular Communication	Hormonal change during a premenstrual or ovulatory phase is also an important factor for the development of FDEIA in this case.	18797181
Parkinson Disease, palladium	Altered Intercellular Communication	Patients with Parkinson disease (PD) have deficits in the neurotransmitter systems important for the normal allocation of attention.	18797255
Intestinal metaplasia, Helicobacter pylori, Atrophic, Inflammatory disease of mucous membrane	Altered Intercellular Communication	In non-NSAID users, eradication of Helicobacter pylori is associated with decreased mucosal inflammation, and may halt the progression to atrophy and intestinal metaplasia, but the continuous use of NSAIDs may interfere with these processes.	18797408
Intestinal metaplasia, Inflammation, Gastritis, Gastritis, Atrophic	Altered Intercellular Communication	Gastritis was assessed according to the updated Sydney classification for activity, chronic inflammation, gastric glandular atrophy, intestinal metaplasia, and H. pylori density.	18797408
Inflammation, Gastritis	Altered Intercellular Communication	Significant less active gastritis, inflammation, and H. pylori density was found in the eradication group compared with the placebo group in both corpus and antrum (P<0.001).	18797408
Inflammation, Thrombosis	Altered Intercellular Communication	Since P-selectin is crucial in inflammation and thrombosis, its reduction by rosuvastatin is potentially relevant in the pathophysiological scenario of PAH.	18797697
Abnormal circulating valine concentration, Inflammation, Psoriasis	Altered Intercellular Communication	The correlation between response to oral cyclosporin therapy and systemic inflammation, metabolic abnormality in patients with psoriasis.	18797895
Abnormal circulating valine concentration, Inflammation, Psoriasis	Altered Intercellular Communication	These results showed the correlation between response of oral cyclosporin therapy and systemic inflammation, metabolic abnormality in patients with psoriasis.	18797895
Hepatic inflammation, Hepatitis, Communicable Diseases, Fibrosis Assessment, Hepatitis C, Chronic	Altered Intercellular Communication	Intrahepatic levels of CXCR3-associated chemokines correlate with liver inflammation and fibrosis in chronic hepatitis C. Chemokines, chemotactic cytokines, may promote hepatic inflammation in chronic hepatitis C virus (HCV) infection through the recruitment of lymphocytes to the liver parenchyma.	18798334
Allergic sensitization, Diabetes Mellitus, Insulin-Dependent, Airway structure	Altered Intercellular Communication	According to the 'Th(1)/Th(2) paradigm', children with type 1 diabetes mellitus (T1DM) should have a lower risk of developing allergic sensitization and, because of the involvement of insulin in modulating airway inflammation, different frequency or severity in allergy-related respiratory manifestations.	18798800
Inflammation, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is an inflammatory process, and high-sensitivity C-reactive protein (Hs-CRP), a marker of inflammation, predicts cardiovascular events in adults.	18798827
Inflammation, Thrombocytosis, Fever, CTCAE, Leukocytosis	Altered Intercellular Communication	ISIR intensity at presentation was determined by 5 parameters of inflammation: sedimentation rate >100 mm/h, thrombocytosis >400,000/microl, hemoglobin <11 g/dl, leukocytosis >11000/microl, and fever >37.5 degrees C. Patients were divided into 3 groups according to ISIR intensity: strong (4-5 parameters present, n=24), moderate (2-3 parameters, n=55) and weak ISIR (0-1 parameter, n=51).	18799050
vascular inflammations	Altered Intercellular Communication	In patients with clinical activity despite nearly normal erythrocyte sedimentation rate (ESR) and C reactive protein (CRP), disease activity could be shown by PET-CT. A long segmental, increased fluoro-deoxyglucose (FDG) uptake in the vessel wall served as confirmation of the vascular inflammation.	18799053
Inflammation, Enthesitis	Altered Intercellular Communication	At specific enthesal sites, history of chronic enthesitic pain and clinical signs of acute inflammation are sensitive and specific for the diagnosis of chronic and/or acute inflammation.	18799083
Degenerative polyarthritis, Inflammation, Pain Distress Question	Altered Intercellular Communication	Osteoarthritis (OA) is a chronic condition, accompanied by inflammation and pain, and it is therefore important to demonstrate long-term efficacy and safety of treatment.	18799092
Sclerosis of the skin, Sample Size Calculation, Inflammation, Pulmonary Fibrosis	Altered Intercellular Communication	Serum Hsp70 levels were increased in SSc patients and were associated with pulmonary fibrosis, skin sclerosis, renal vascular damage, oxidative stress, and inflammation.	18799101
Inflammation, Malnutrition, Diabetes Mellitus	Altered Intercellular Communication	These results demonstrate that the serum beta(2)-M level is a significant predictor of mortality in haemodialysis patients, independent of haemodialysis duration, diabetes, malnutrition and chronic inflammation, suggesting the clinical importance of lowering serum beta(2)-M in these patients.	18799606
Inflammation, Hyperparathyroidism, Deficient Food Intake	Altered Intercellular Communication	In summary EPO resistance in the pediatric dialysis cohort was predicted by nutritional deficits, inflammation, poor dialysis, and hyperparathyroidism, while iron and folate deficits were the major determinants in adults.	18800231
Longevity	Altered Intercellular Communication	Longevity factors, such as SIRT1 and its activators, might regulate the efficiency of the NF-kappaB signaling, the major outcome of which is inflamm-aging via proinflammatory responses.	18800364
Osteopenia	Altered Intercellular Communication	Major phenolic compounds in olive oil modulate bone loss in an ovariectomy/inflammation experimental model.	18800805
Inflammation, Osteopenia	Altered Intercellular Communication	As expected, an induced chronic inflammation provoked further bone loss at total, metaphyseal, and diaphyseal sites in ovariectomized rats.	18800805
Inflammation, Lymphoma	Altered Intercellular Communication	In the present case, long-standing chronic inflammation induced by PET mesh may have been associated with the development of lymphoma.	18801089
Primary malignant neoplasm	Altered Intercellular Communication	Median plasma DNA concentrations were higher in patients with cancer and major organ inflammation.	18801348
Inflammation, Primary malignant neoplasm, Acute abdominal pain	Altered Intercellular Communication	Plasma DNA may have a role in patients with acute abdominal pain as a marker for inflammation and cancer, and a predictor of intensive care unit admission/mortality.	18801348
Inflammation, Tooth Loss, Cerebrovascular accident	Altered Intercellular Communication	Tooth loss, systemic inflammation, and prevalent stroke among participants in the reasons for geographic and racial difference in stroke (REGARDS) study.	18801482
Inflammation, Tooth Loss, Periodontal Diseases, Cerebrovascular accident	Altered Intercellular Communication	Periodontal disease results in tooth loss, may contribute to systemic inflammation, and is associated with stroke.	18801482
Inflammation, Tooth Loss, Cerebrovascular accident	Altered Intercellular Communication	Tooth loss, which varied with race, but not region of residence, was associated with inflammation markers and stroke.	18801482
Inflammation	Altered Intercellular Communication	Neutrophil number and activity were increased only during inflammation in both diseases.	18801925
Inflammation, physiopathological	Altered Intercellular Communication	It is characterized by airway dysfunction and inflammation.	18802103
Uveitis	Altered Intercellular Communication	Sixty-seven inflammation- and autoimmune-associated genes were found differentially expressed in uveitis patients, with 28 of those genes being validated by real-time PCR.	18802119
ARCN1 gene, Inflammation	Altered Intercellular Communication	We conclude that YKL-40 is up-regulated in COPD, in which it may contribute to tissue inflammation and remodeling by sustaining the synthesis of proinflammatory and fibrogenic chemokines and of metalloproteinases by alveolar macrophages.	18802121
Airway structure	Altered Intercellular Communication	Prostaglandin D(2) (PGD(2)) participates in airway inflammation.	18802357
Inflammation	Altered Intercellular Communication	The signal intensity in a series of DWI was measured and the apparent diffusion coefficient (ADC) values were calculated to differentiate inflammation from normal tissue.	18803364
Inflammation	Altered Intercellular Communication	As the inflammation decreased, the bright signal faded to an iso-signal and the ADC values returned to their normal level.	18803364
Inflammation, Hypertriglyceridemia	Altered Intercellular Communication	These data confirm impaired metabolism of fat among smokers and suggest that mechanisms other than inflammation or insulin resistance may explain the observed hypertriglyceridemia among smokers.	18804210
Inflammation, SLC25A20 gene	Altered Intercellular Communication	Despite a generally higher level of systemic inflammation in T2DM, the inflammatory marker IL-6 remained significantly associated with CAC score, particularly in those subjects with lower AAC scores.	18804762
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	CD44 expression is increased in inflammatory conditions such as rheumatoid arthritis and CD44 variant 3 (CD44v3) expression may be associated with inflammation.	18804988
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	CD44 expression is increased in inflammatory conditions such as rheumatoid arthritis and CD44 variant 3 (CD44v3) expression may be associated with inflammation.	18804988
Degenerative polyarthritis, Inflammation, Cartilage Diseases	Altered Intercellular Communication	Evaluation of a Photographic Chondropathy Score (PCS) for pathological samples in a study of inflammation in tibiofemoral osteoarthritis.	18805026
Inflammation	Altered Intercellular Communication	Synovial inflammation was associated with higher PCS and radiological JSN scores (r values 0.43-0.48), irrespective of diagnosis.	18805026
Degenerative polyarthritis, Inflammation, Cartilage damage, Synovitis	Altered Intercellular Communication	Synovial inflammation was associated with increased OA structural severity, suggesting a possible role of chronic synovitis in cartilage damage.	18805026
Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Atrial fibrillation (AF) may be caused by structural and electrophysiological changes in the atria induced by inflammation.	18805111
Inflammation	Altered Intercellular Communication	Increased expression levels in glandular inflammation have been described previously albeit not in AANTs.	18805729
Inflammation, Meibomian Cyst	Altered Intercellular Communication	Lack of inflammation, lack of fluctuation in size, gradual continued slow growth, and delayed onset of recurrence may help to differentiate tarsal cyst from recurrent chalazion.	18806654
Chronic inflammation of orbit, Fibrosis Assessment, Malignant melanoma of choroid	Altered Intercellular Communication	Chronic orbital inflammation and fibrosis after retrobulbar alcohol and chlorpromazine injections in a patient with choroidal melanoma.	18806668
ARCN1 gene, Inflammation	Altered Intercellular Communication	Biomarkers of systemic inflammation in stable and exacerbation phases of COPD.	18807087
ARCN1 gene, Inflammation	Altered Intercellular Communication	The nature and course of systemic inflammation in COPD is important since there is a potential for anti-inflammatory therapy.	18807087
ARCN1 gene, Inflammation	Altered Intercellular Communication	The objective of the current study was to assess biomarkers of systemic inflammation in stable and exacerbation phases of COPD patients as compared to healthy controls.	18807087
Inflammation, Therapeutic Tumor Infiltrating Lymphocytes	Altered Intercellular Communication	The dural biopsy specimen showed chronic inflammation with infiltration of lymphocytes and histiocytes.	18807253
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Thus, MetS was associated with elevated liver enzymes (especially, GGT), and inflammation (hsCRP).	18807290
Inflammation, Pericarditis, Constrictive	Altered Intercellular Communication	Constrictive pericarditis after open heart surgery may be caused by inflammation of the pericardium; an old, fibrotic haemopericardium, which may be diffuse or loculated; pericardial adhesions; or a combination of these entities.	18808077
vascular inflammations, Atherosclerotic lesion, Atherosclerosis	Altered Intercellular Communication	DCs (dendritic cells) are present in atherosclerotic lesions leading to vascular inflammation, and the number of vascular DCs increases during atherosclerosis.	18808367
Inflammation, Primary malignant neoplasm, Anemia	Altered Intercellular Communication	Anemia of aging: the role of chronic inflammation and cancer.	18809094
Inflammation, Cerebral Infarction, Cerebrovascular accident	Altered Intercellular Communication	We have sought to relate C-reactive protein (CRP), a peripheral marker of inflammation frequently elevated in stroke patients, with aetiology and prognosis of acute cerebral infarction.	18810599
Inflammation, Atherosclerosis	Altered Intercellular Communication	Measures of inflammation, such as hs-CRP, and indices of atherosclerosis, such as CCS, are likely to provide distinct information regarding cardiovascular risk.	18810717
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Fecal markers of inflammation used as surrogate markers for treatment outcome in relapsing inflammatory bowel disease.	18810778
Inflammation, Acute anterior uveitis	Altered Intercellular Communication	Longitudinal study of anterior segment inflammation by ultrasound biomicroscopy in patients with acute anterior uveitis.	18811638
Postprandial Period, Hypertension, CTCAE	Altered Intercellular Communication	High-fat meal can induce postprandial inflammation response in patients with essential hypertension.	18812659
Inflammation, Blood Glucose	Altered Intercellular Communication	Admission glycemia and markers of inflammation are independent outcome predictors in primary PCI in non-diabetic patients.	18813179
Inflammation, Infection	Altered Intercellular Communication	Latent local or systemic infections or aseptic inflammation with subsequent local immune suppression seem to be responsible.	18813908
Inflammation, Obesity	Altered Intercellular Communication	Oxidative stress and inflammation are involved in the development of obesity.	18814207
Inflammation, Borrelia burgdorferi, Lyme Neuroborreliosis	Altered Intercellular Communication	Persisting atypical and cystic forms of Borrelia burgdorferi and local inflammation in Lyme neuroborreliosis.	18817547
Inflammation	Altered Intercellular Communication	The long latent stage seen in syphilis, followed by chronic central nervous system infection and inflammation, can be explained by the persistence of atypical cystic and granular forms of Treponema pallidum.	18817547
Inflammation, Granuloma	Altered Intercellular Communication	There were two false positive cases for PET/MRI fusion that were confirmed by biopsy: chronic inflammation; and foreign body granulomas.	18817662
Inflammation	Altered Intercellular Communication	Serum values of orosomucoid were higher in patients with increased UOER than in healthy controls (P<.001), but were still within reference limits, suggesting chronic low-grade inflammation.	18818101
Inflammation	Altered Intercellular Communication	We therefore hypothesize that increased levels of UOER may be caused by local renal production of orosomucoid due to chronic low-grade inflammation.	18818101
Inflammatory abnormality of the eye	Altered Intercellular Communication	The intravenous bisphosphonates appear to be linked with more severe ocular inflammation than the orally administered ones.	18818218
Inflammation, Lymphoma	Altered Intercellular Communication	Our findings suggest that the Foxp3(+) T-regulatory cell frequency in the MSG lesions of SS patients correlates with inflammation grade and certain risk factors for lymphoma development.	18818377
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Effect of atorvastatin on inflammation and outcome in patients with type 2 diabetes mellitus on hemodialysis.	18818679
Inflammation, Uterine Cervicitis	Altered Intercellular Communication	The presence of cervicitis was assessed by grading the amount of inflammation on each woman's cervical biopsy.	18820542
Inflammation, Thrombophilia	Altered Intercellular Communication	Metabolic predictors of inflammation, adhesion, and coagulability in healthy younger-aged adults.	18820652
ARCN1 gene, Pseudomonas aeruginosa, Bronchitis	Altered Intercellular Communication	Tobramycin Nebulizer Solution in severe COPD patients colonized with Pseudomonas aeruginosa: effects on bronchial inflammation.	18821068
Pain Distress Question, Inflammation, Central Nervous System Sensitization	Altered Intercellular Communication	However, pain in these patients might be associated with central nervous sensitization rather than peripheral inflammation and injury.	18821657
Tumor necrosis, Fibrinoid necrotizing inflammation	Altered Intercellular Communication	Tumor necrosis factor alpha drives cadherin 11 expression in rheumatoid inflammation.	18821672
Refractory anemias, Inflammation	Altered Intercellular Communication	However, we have previously demonstrated a high prevalence of imaging-detected synovial inflammation in RA patients who were in clinical remission.	18821687
Refractory anemias, Inflammation	Altered Intercellular Communication	Subclinical joint inflammation detected by imaging techniques explains the structural deterioration in RA patients in clinical remission who are receiving conventional therapy.	18821687
Inflammation, Myositis	Altered Intercellular Communication	CD85j is expressed in PM and sporadic IBM at the sites of partial invasion and in DM in perivascular inflammation, paving the way for dissecting the role of CD85j in the pathogenesis of inflammatory myopathies.	18821690
Immunocompromised Host	Altered Intercellular Communication	AGE-induced mast cell apoptosis may contribute to the immunocompromised and inflammatory conditions.	18822320
Kidney Failure, Chronic, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The kynurenines are associated with oxidative stress, inflammation and the prevalence of cardiovascular disease in patients with end-stage renal disease.	18823890
Kidney Failure, Chronic, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Increased oxidative stress (SOX), inflammation and prevalence of cardiovascular disease (CVD) have been reported in end-stage renal disease (ESRD), but their associations with kynurenine (KYN) pathway activation remain unknown.	18823890
Kidney Failure, Chronic, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	These results suggest a relationship between KYN pathway activation and increased SOX, inflammation and CVD prevalence in ESRD patients.	18823890
Refractory anemias, Inflammation	Altered Intercellular Communication	Duration of RA and a haematological measure of systemic inflammation (erythrocyte sedimentation rate; ESR) were obtained from hospital records.	18825587
Refractory anemias, Inflammation, Fatigue	Altered Intercellular Communication	Unexpectedly, RA duration did not predict fatigue after 1 year, although lower baseline inflammation did (controlling for baseline fatigue and other disease impact variables).	18825587
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	The prostaglandin E2 EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis.	18825663
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	Inflammation has emerged as an important factor in disease progression in human and transgenic models of amyotrophic lateral sclerosis (ALS).	18825663
Inflammation, Amyloidosis	Altered Intercellular Communication	In alternate models of inflammation, including the lipopolysaccharide model of innate immunity and the APPSwe-PS1DeltaE9 model of amyloidosis, deletion of EP2 also reduced expression of proinflammatory genes.	18825663
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Inflammation appears to be important in the pathogenesis of acute myocardial infarction (AMI).	18827373
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Inverse association between histologic inflammation in needle biopsy specimens and prostate cancer in men with serum PSA of 10-50 ng/mL.	18829081
Inflammation, Bronchopulmonary Dysplasia, Structure of posterior cerebral artery	Altered Intercellular Communication	A significant difference was found in the incidence of histologic inflammation between the PCa (40.7%) and BPD (73.7%) groups.	18829081
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Among the factors examined, the PSAD and the presence of histologic inflammation appeared to be independently associated with the detection of PCa.	18829081
Inflammation, Carotid Arteries	Altered Intercellular Communication	Carotid artery lesions from symptomatic patients are characterized by inflammation and neovascularization.	18829234
Inflammation, Neurologic Dysfunction	Altered Intercellular Communication	Unexplained worsening of neurological dysfunction despite bortezomib discontinuation, with prominent motor involvement and CSF signs of inflammation, may be the clues to this complication.	18829381
Hyperemia, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Upper oesophagastroduodenoscopy in these cases showed antral hyperaemia and histopathology showed non-caseating gastric granulomatous inflammation.	18830524
Inflammation	Altered Intercellular Communication	Its modulation by inflammation and therapy suggests that glucocorticoids play a conflicting role by suppressing not only inflammation but also putative mechanisms of repair.	18830904
Pain Distress Question, Inflammatory abnormality of the eye	Altered Intercellular Communication	During the postoperative follow-up, the patient developed eye pain and persistent ocular inflammation.	18831425
Pain Distress Question, Inflammation	Altered Intercellular Communication	Wound healing was completed in 10 days and a stable ocular surface was restored without pain or inflammation.	18831429
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	The role of inflammation in atrial fibrillation following open heart surgery.	18831903
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	This study investigated the role of systemic inflammation in the development of atrial fibrillation (AF) after coronary artery bypass grafting (CABG).	18831903
Inflammation, Dental Plaque	Altered Intercellular Communication	Intravenous infusion of a single dose of reconstituted HDL led to acute changes in plaque characteristics with a reduction in lipid content, macrophage size, and measures of inflammation.	18832751
Inflammation, Cardiac Death, Ventricular Dysfunction, Left, Congestive heart failure, Myocardial	Altered Intercellular Communication	Levels of BNP (associated with left ventricular dysfunction, positive if >200 pg/ml), H-FABP (marker of myocardial damage, positive if >4.1 ng/ml), and PTX3 (marker of inflammation, positive if >4.0 ng/ml) were measured in 164 consecutive CHF patients, and patients were prospectively followed with endpoints of cardiac death or rehospitalization.	18832778
Inflammation, Cholelithiasis	Altered Intercellular Communication	Diminished expression of apical sodium-dependent bile acid transporter in gallstone disease is independent of ileal inflammation.	18832832
Inflammation, Cholelithiasis	Altered Intercellular Communication	To test whether subclinical ileal inflammation contributes to gallstone disease.	18832832
Inflammation	Altered Intercellular Communication	The gallstone-associated ileal biopsies exhibited no histological inflammation.	18832832
Crohn Disease, Inflammation, Biliary calculi	Altered Intercellular Communication	Although the expression of ASBT was similarly diminished in both gallstone and Crohn's disease, subclinical ileal inflammation does not appear to be relevant in gallstone patients.	18832832
Inflammation, Age related macular degeneration	Altered Intercellular Communication	Basic research has shown that early processes in the development of age-related macular degeneration (ARMD) are related to inflammation.	18832975
Symptoms, Orchitis	Altered Intercellular Communication	The correlation between the obstruction symptoms and appendicular inflammation was supposed in 3 patients.	18833162
Inflammation, Tuberculosis, Cyst	Altered Intercellular Communication	Of the 118 benign aspirates, the cytodiagnosis was acute/chronic inflammation in 24, tuberculosis in 1, benign cyst in 10 and a benign aspirate, not otherwise specified, in the remaining 83 cases.	18833812
Chorioretinal degeneration, Inflammation, VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding), Cataract, Glaucoma, CTCAE, Macule	Altered Intercellular Communication	Outcome measures were: VA, persistent inflammation, cataracts, glaucoma, macular lesions, chorioretinal degeneration, and vitiligo at three years after onset.	18834575
Cataract, Inflammation, Chorioretinal degeneration	Altered Intercellular Communication	Good VA at one month was associated with greater likelihood of good VA at three years (odds ratio [OR], 43.9; P = .02), less persistent inflammation (OR, 0.5; P = .006), cataract (OR, 0.10; P = .01), and chorioretinal degeneration (OR, 0.2; P = .04).	18834575
Vasculitis, Retinitis, Immunocompromised Host	Altered Intercellular Communication	Clinical features associated with positive PCR results were retinal vascular inflammation (P < .001), optic nerve involvement (P = .008), immunocompromised state (P = .039), and extensive retinitis (P = .002).	18834576
Retinitis, Optic Neuritis	Altered Intercellular Communication	Cases with vascular or optic nerve inflammation, extensive retinitis, or immunocompromise are more likely to have positive PCR results and may benefit from PCR testing of aqueous humor.	18834576
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Chronic inflammatory bowel diseases such as ulcerative colitis (UC) are associated with differential expression of genes involved in inflammation and tissue remodeling.	18835392
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	We examined whether miRNAs are differentially expressed in UC tissues and are associated with expression of genes that regulate inflammation.	18835392
Inflammation, chronic, Enteric neuronal degeneration	Altered Intercellular Communication	Chronic chagasic patients with gastrointestinal involvement exhibit inflammation and degeneration of enteric neurons.	18835625
Inflammation	Altered Intercellular Communication	These findings suggest that a milieu with high MMP-9 may be indicative of inflammation and poor wound healing.	18835949
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Subclinical inflammation is linked with the development of type 2 diabetes, and epidemiologic data suggest that this association may be stronger in women.	18835953
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	We sought to assess vascular reactivity in patients with chronic obstructive pulmonary disease (COPD) and respective control subjects, and to investigate the relation between vascular function and airflow obstruction and systemic inflammation.	18836149
ARCN1 gene, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Airflow obstruction and systemic inflammation may increase the risk of cardiovascular disease in patients with COPD.	18836149
Neurogenic Inflammation, Carotid Stenosis, Structure of intracranial artery	Altered Intercellular Communication	The degree of atherogenic inflammation in asymptomatic intracranial artery stenosis may be less than that in extracranial carotid artery stenosis.	18836266
Inflammation, Swelling	Altered Intercellular Communication	A 50-year-old woman suffered from recurrent swelling and inflammation in the region of the medial portion of the lower eyelid 24 years after right-sided dacryocystorhinostomy.	18836728
PTHLH gene, Pancreatic carcinoma, Malignant Neoplasms, Hypercalcemia, CTCAE	Altered Intercellular Communication	We report a rare case of adenosquamous carcinoma of the pancreas associated with humoral hypercalcemia of malignancy (HHM) in which parathyroid hormone-related protein (PTH-rP) was identified as the causative factor of hypercalcemia.	18836809
Inflammation, Arthritis	Altered Intercellular Communication	Amongst new-patients (72), 13/39 (33.3%) referred with inflammatory arthritis had no MSUS evidence of inflammation in or around joints.	18836893
Tinea corporis (disorder), Acute inflammation	Altered Intercellular Communication	Tinea corporis with acute inflammation caused by Trichophyton tonsurans.	18837705
Acute inflammation	Altered Intercellular Communication	A 13-year-old Japanese boy presented with acute skin inflammation on the extremities.	18837705
Inflammation, Tinea corporis (disorder)	Altered Intercellular Communication	Tinea corporis with inflammation necessitates systemic antifungal therapy.	18837705
HD Term Type, Inflammation, Dyssomnias	Altered Intercellular Communication	Poor physical functioning in chronic HD patients, as measured by the HAP, is associated with sleep disturbance, after controlling for inflammation and dialysis adequacy.	18837765
palladium, Smell Perception	Altered Intercellular Communication	However, olfactory deficits do not always worsen over time despite progression of disease raising the possibility of additional pathobiological mechanisms contributing to olfactory functions in PD, such as changes in olfactory neurotransmitter functions.	18838108
palladium	Altered Intercellular Communication	Neurotransmitter changes, such as altered dopaminergic status, may also better explain the selective nature of odor identification deficits in PD.	18838108
Inflammation, Albuminuria, diabetic, Diabetes Mellitus	Altered Intercellular Communication	The involvement of chronic inflammation in albuminuria and renal function was investigated in a cross-sectional study of 320 type 2 diabetic Chinese patients from the Singapore Diabetes Cohort Study.	18839132
Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	In this report, a CT scan was effective in demonstrating both the presence and the extent of inflammation of lupus profundus in two patients with systemic lupus erythematosus (SLE).	18839269
Chronic dacryocystitis, Inflammation	Altered Intercellular Communication	Chronic dacryocystitis is the inflammation of lacrimal sac, frequently caused by bacteria.	18839635
Pain Distress Question, Inflammation	Altered Intercellular Communication	To conclude, parflex is an effective analgesic, anti-inflammatory drug that has a valuable therapeutic option for controlling pain and inflammation after surgical procedures.	18839656
Communicable Diseases, Inflammation	Altered Intercellular Communication	We investigated intensive care unit (ICU) patients with respect to the impact of Lp299v on C. difficile colonisation and on gut permeability and parameters of inflammation and infection in that context.	18840110
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Inflammation in an ESRD patient may impact responsiveness to erythropoiesis-stimulating agent (ESA) therapy.	18840893
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	NF-kappaB, a major transcription factor controlling inflammation, is activated in Alzheimer's disease (AD) brains.	18841008
Inflammation, Apolipoprotein E, Data types - Address	Altered Intercellular Communication	Apolipoprotein E (ApoE) epsilon4 allele, the major genetic risk factor of AD, is associated with hyperactivation of NF-kappaB and enhanced brain inflammation.	18841008
Vascular Diseases, Inflammation	Altered Intercellular Communication	In 428 patients with mental illness we have investigated the relation of vascular disease to diagnoses, and a biochemical parameter, C-reactive protein (CRP), which is associated with inflammation and vascular disease.	18841009
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	In the multivarate analysis, after adjustment for cardiovascular risk factors, intima-media thickness was independently associated with inflammation and endothelial dysfunction in older adults (p < 0.01).	18842208
Inflammation, Blood Vessel, Atherosclerosis	Altered Intercellular Communication	Besides age, systemic inflammation and vascular damage are associated with subclinical atherosclerosis in asymptomatic subjects.	18842208
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	Subclinical inflammation is a novel risk factor of cardiovascular diseases and type 2 diabetes.	18842390
Inflammation, Mirizzi Syndrome, Cholelithiasis, Biliary calculi	Altered Intercellular Communication	Mirizzi syndrome is a rare complication of cholelithiasis, characterized by the narrowing of the common hepatic duct as a result of mechanical compression and/or inflammation due to biliary calculus impacted in the infundibula of the gallbladder or in the cystic duct.	18842500
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Home use of vegetable oils, markers of systemic inflammation, and endothelial dysfunction among women.	18842776
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	However, a single measurement of serum YKL-40 from an individual may not have a prognostic value, and serum YKL-40 alone cannot be a good biomarker for cancer because serum YKL-40 can be elevated in patients with other diseases characterized by inflammation and tissue remodeling.	18843001
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The association of physical activity with reduced chronic inflammation provides a potential mechanism, yet few studies have directly related inflammatory markers to cancer incidence.	18843014
Inflammation, Carcinoma of lung	Altered Intercellular Communication	The relation among physical activity, inflammation, and lung cancer risk was evaluated in a prospective cohort of 4,831 subjects, 43 to 86 years of age, in Beaver Dam, Wisconsin.	18843014
Inflammation, Skin Infection, CTCAE, Psoriasis	Altered Intercellular Communication	These results show that cytokine-induced cell-surface expression of CEACAM1 by keratinocytes in the context of a psoriatic environment might contribute to the persistence of neutrophils and thus to ongoing inflammation and the decreased propensity for skin infection, typical for patients with psoriasis.	18843289
Inflammation, Carcinogenesis, Adenomatous Polyps	Altered Intercellular Communication	It has been shown that local chronic inflammation may lead to colorectal carcinogenesis via adenomatous polyps.	18844497
Inflammation, Neoplasms	Altered Intercellular Communication	Interleukin-6 and C-reactive protein are biomarkers of inflammation and indicators of the immune response to tumors.	18844497
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Chronic inflammation has been implicated in the development of colorectal cancer (CRC).	18844617
Inflammation, Malignant Neoplasms, Cardiovascular Diseases	Altered Intercellular Communication	The presence of low-grade systemic inflammation, as determined by an elevation of high-sensitivity C-reactive protein (CRP), has been associated with an increased risk of cardiovascular diseases and cancers.	18844617
Inflammation, Colorectal Neoplasms	Altered Intercellular Communication	These data support the association between chronic inflammation and colorectal neoplasia in men and provide new insights into the underlying mechanisms that warrant further investigation.	18844617
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	Chronic inflammation of the intestinal wall is the common characteristic of Crohn's disease and ulcerative colitis; disorders, which in some cases can be difficult to distinguish.	18844621
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	PAI-1-positive neurons in inflammatory bowel disease are linked to chronic inflammation in Crohn's disease, implying PAI-1 as a potential parameter for the differential diagnosis between Crohn's disease and ulcerative colitis.	18844621
Crohn Disease, Chronic ulcerative colitis	Altered Intercellular Communication	PAI-1 was found in a subset of neurons primarily located in the submucosal plexus of the small and large intestine in 24 of 28 cases (86%) with Crohn's disease, but in none of 17 cases with chronic ulcerative colitis and other severe inflammatory conditions in the intestinal wall.	18844621
Inflammation, Metabolic Syndrome X, MS gene	Altered Intercellular Communication	Metabolic syndrome (MS) and "low grade" systemic inflammation (LGSI) are very common findings in the older population.	18845301
Inflammation, Goblet Cells, Squamous metaplasia	Altered Intercellular Communication	The histologic examinations showed 11.9% mucous cell prosoplasia, 55.9% squamous metaplasia, 15.3% glandular epithelium, and 33.9% inflammation.	18848095
Inflammation, Heart failure, Cerebrovascular accident	Altered Intercellular Communication	In multivariate models adjusted for demographics, cardiovascular risk factors, and inflammation, prevalent stroke (OR, 95% CI: 1.55, 1.16-2.08) and heart failure (OR, 95% CI: 1.80, 1.40-2.31) were independent predictors of rapid kidney decline.	18848325
Refractory anemias, Inflammation	Altered Intercellular Communication	The IL-6-174C-allele may associate with CVD in RA patients and possibly exerts its effect via increased inflammation.	18848327
Inflammation	Altered Intercellular Communication	Adipokines may directly influence vessel wall homeostasis by influencing the function of endothelial cells, arterial smooth muscle cells, and modulating inflammation.	18848328
Minimal Disseminated Disease, Unipolar Depression	Altered Intercellular Communication	Serotonin transporter (5-HTT) and 5-HT receptor (5-HTR) involved in the neurotransmission of 5-HT may play an important role in the development of major depression disorder (MDD).	18848359
Inflammation, Secondary malignant neoplasm of liver	Altered Intercellular Communication	Evaluation of the prognostic value of systemic inflammation and socioeconomic deprivation in patients with resectable colorectal liver metastases.	18848775
Pancreatitis, Acute, Pancreatic Anastomotic Leakage, Inflammation	Altered Intercellular Communication	Protease activation, pancreatic leakage, and inflammation in acute pancreatitis: differences between mild and severe cases and changes over the first three days.	18849642
Inflammation	Altered Intercellular Communication	There is increasing evidence to support the influence of inflammation in the pathogenesis of AF.	18850246
Autoimmune Diseases, Inflammation, Atherosclerosis	Altered Intercellular Communication	Laboratory study showed absolutely all negative markers of inflammation, autoimmune disorders, or atherosclerosis.	18850320
Structure of pelvic girdle, Musculoskeletal Pain	Altered Intercellular Communication	Polymyalgia rheumatica (PMR) is an inflammatory condition of unknown etiology characterized by aching and stiffness in the shoulder, pelvic girdle and the neck.	18850321
Keratitis, Corneal Opacity, Unspecified visual loss	Altered Intercellular Communication	The patient had recurrent episodes of corneal inflammation that became more frequent and severe during the follow-up, and caused severe corneal opacities and visual loss.	18850565
Corneal Scar, Keratitis	Altered Intercellular Communication	The treatment was continued for 1 year and the patient achieved a complete remission of corneal inflammation with resolution of corneal scarring and normalization of intraocular pressure.	18850565
Keratitis, Interstitial keratitis	Altered Intercellular Communication	In this child with recurrent episodes of interstitial keratitis, topical cyclosporine 2% has been shown to be a safe and effective alternative for treating corneal inflammation.	18850565
Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	Tumor cell proliferation and migration, as well as metastasis formation, can be affected by several neurotransmitters, which therefore seem to be involved in the most important aspects of the malignant phenotype.	18852493
Tissue damage, Chronic inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Treatment with glycine is likely to have a beneficial effect on innate and adaptive immune responses and may help prevent tissue damage caused by chronic inflammation in patients with Type 2 diabetes.	18852529
Periodontitis	Altered Intercellular Communication	X-ray orthopanthomography and magnetic resonance imaging of the neck confirmed several areas of periodontitis around the previous dental implants and right mastoid inflammation.	18852592
Hiatal Hernia, Esophageal	Altered Intercellular Communication	A barium swallow and fibre-optic endoscopy also revealed a small sliding hiatus hernia and distal chronic oesophageal inflammation.	18852592
Inflammation, Cancer-related fatigue, Calcinosis, Traumatic injury, Chronic Kidney Diseases	Altered Intercellular Communication	Myringosclerosis is a scar of the tympanic membrane lamina propria, resulting from trauma or inflammation, characterized by proliferation of collagen, hyalinization, calcium and phosphate deposits and cartilaginous or osseous metaplasia of the middle ear mucosa, a sequence that is similar to that taking place in other types of pathologic calcification, common in chronic renal failure (CRF).	18852973
Intestinal metaplasia, Inflammation, Lithiasis	Altered Intercellular Communication	Intestinal metaplasia is extremely frequent in gallbladders with inflammation and lithiasis, especially in younger patients.	18853030
Blindness, Orbital Pseudotumor	Altered Intercellular Communication	Early, appropriate evaluation and management observing signs and symptoms of orbital inflammation are required to prevent blindness.	18853645
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Degree of inflammation and fibrosis were more mild among those with steatosis than those without.	18853998
Refractory anemias, Inflammation, Disease	Altered Intercellular Communication	We therefore assessed forearm microvascular endothelial function in patients with RA and determined its relationship to RA disease activity and inflammation.	18854346
Inflammation, Disease	Altered Intercellular Communication	Parameters of RA disease activity and inflammation were also checked.	18854346
Refractory anemias, Inflammation, physiopathological	Altered Intercellular Communication	In this large cross-sectional study, we found for the first time systemic inflammation (CRP) to be independently associated with microvascular dysfunction in patients with RA.	18854346
Refractory anemias, Cardiovascular morbidity, Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	RA is a chronic autoimmune inflammatory condition associated with increased cardiovascular morbidity and mortality.	18854346
Granulomatous inflammation, Diffuse alveolar hemorrhage, Capillaritis	Altered Intercellular Communication	Pathological findings included alveolar hemorrhage (60%), granulomatous inflammation (46%), and capillaritis (38%).	18854674
Inflammation	Altered Intercellular Communication	For several anatomical localisations of extranodal marginal zone B-cell lymphoma of MALT type (eMZBCL), an association with chronic inflammation caused by microbiological agents (e.g.	18854998
Inflammation, Lymphoma	Altered Intercellular Communication	16S-rDNA library construction in combination with RFLP screening and phylogenetic analyses, hereafter described as SHARP screening, is a cultivation-independent tool for analysing the microbial environment in chronic inflammation processes giving rise to extranodal marginal zone B-cell lymphomas of MALT-type.	18854998
Inflammation, Granuloma, Fibrosis Assessment, Swelling, Caseous necrosis	Altered Intercellular Communication	Anti-tuberculosis treatment did not improve the swelling in the lacrimal and submandibular glands, and a biopsy specimen of the lacrimal gland showed inflammation, with abundant lymphoid follicles with fibrosis and granuloma without caseous necrosis.	18855098
Inflammation	Altered Intercellular Communication	In MHD patients, ferritin values above 500 ng/ml, especially in paradoxical conjunction with low ISAT, are associated with inflammation.	18922994
Inflammation, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	Strategies to dissociate inflammation from iron metabolism to mitigate the confounding impact of inflammation on iron and to improve iron treatment responsiveness may improve anemia management in chronic kidney disease.	18922994
Acute Coronary Syndrome, Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	In acute coronary syndromes (ACS), oxidation and inflammation have very important roles and in-vitro studies have demonstrated that gamma-glutamyl transferase (GGT) participates in such oxidative and inflammatory reactions.	18923245
Cessation of life, Airway Obstruction, Laryngitis	Altered Intercellular Communication	Inflammation of laryngeal tissue with sudden obstruction of the airway resulted in death in one patient.	18924592
Inflammation, Thrombocytosis	Altered Intercellular Communication	In conclusion, reactive thrombocytosis in children aged 1 up to 24 months is frequent and unrelated to markers of disease activity or degree of inflammation.	18925508
Osteomyelitis, Inflammation	Altered Intercellular Communication	This initiates the cascade of events leading to inflammation of the mucosa and submucosa, with secondary pyogenic osteomyelitis of the turbinate bone.	18926001
Inflammation, Asthma	Altered Intercellular Communication	Endothelial activation and systemic inflammation in obese asthmatic children.	18926053
Inflammation, Asthma	Altered Intercellular Communication	The objective of this article is to investigate whether asthma could exacerbate the endothelial activation and to determine the relationship between systemic inflammation and endothelial activation in obese asthmatic children.	18926053
Inflammation, Asthma	Altered Intercellular Communication	Significant association between systemic inflammation and endothelial activation was observed in asthmatic children.	18926053
Inflammation, Autonomic nervous system disorders	Altered Intercellular Communication	Inflammation may provide a link between risk factors, autonomic dysfunction, and CAD.	18926158
Inflammation	Altered Intercellular Communication	Autonomic dysregulation leading to inflammation may represent one pathway through which traditional risk factors promote development of CAD.	18926158
Interstitial inflammation	Altered Intercellular Communication	It is characterized by interstitial inflammation rich in foamy macrophages and by fibroblastic connective tissue expanding into the airway and alveolar lumen.	18926305
Inflammation, Neoplasms	Altered Intercellular Communication	The matrix metalloproteinase MT1-MMP (MMP-14) is an important player in wound healing, bone development, angiogenesis, inflammation and tumour invasion.	18927121
Inflammation, Bone necrosis	Altered Intercellular Communication	There was no evidence of inflammation or osteonecrosis.	18927251
Inflammation, Glioblastoma Multiforme Pathway	Altered Intercellular Communication	These findings indicate that polymorphisms in inflammation pathway genes may play an important role in glioma survival.	18927306
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation may play a role in the pathogenesis of atrial fibrillation.	18927423
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Inflammation is a major risk factor for atherosclerotic plaque rupture and clinical events.	18927453
Cerebrovascular, Thrombosis	Altered Intercellular Communication	Platelet C4d may be a biomarker as well as pathogenic clue that links cerebrovascular inflammation and thrombosis.	18927458
Inflammation, Aortic sclerosis, Cardiovascular Diseases	Altered Intercellular Communication	The aim of the study was to evaluate several mediators of inflammation in patients with aortic sclerosis in relation to severity of cardiovascular disease.	18928057
Inflammation	Altered Intercellular Communication	Our results support the hypothesis of an "inflammatory pattern" associated with AS pathology and suggest the persistence of a chronic inflammation in patients who experienced acute coronary events.	18928057
Refractory anemias, Inflammation	Altered Intercellular Communication	As used in treating active RA, it displays an initiating time shorter than non-steroid drugs, and could abate the inflammation of joint synovial membrane and adjust the immunity of patients better, so as to enhance the total effectiveness.	18928105
Diabetic Nephropathy, Inflammation, Calcification of coronary artery, Chronic Kidney Diseases	Altered Intercellular Communication	Despite more advanced abnormalities in calcium-phosphate balance parameters and more active inflammation in peritoneal dialysis subjects we failed to demonstrate any statistically significant difference in coronary artery calcification score between patients with diabetic nephropathy on peritoneal dialysis and those with chronic kidney disease stages 2-4.	18928155
Kidney Failure, Chronic, Inflammation, Erythropoietin	Altered Intercellular Communication	[Chronic inflammation, oxidative stress and effects of erythropoetin in end-stage renal disease patients].	18928173
HD Term Type, Inflammation	Altered Intercellular Communication	This important result can be explained the know EPO effect of endothelial cells apoptosis and inhibiting inflammation induced by HD.	18928173
HD Term Type, Inflammation	Altered Intercellular Communication	Chronic inflammation is a common cause of CVD, hyporesponsiveness to EPO and endothelial dysfuncton in HD patients.	18928173
Rosacea, Acne	Altered Intercellular Communication	The patient had never previously presented from acne or rosacea and the question of the responsibility of hormonal changes induced by stimulating ovulation or pregnancy can be raised.	18929918
Inflammation	Altered Intercellular Communication	We investigated the correlations between the plasma levels of APO and two markers of inflammation: lipoprotein associated phospholipase A2 (Lp-PLA2) and myeloperoxidase (MPO).	18930040
Airway structure	Altered Intercellular Communication	This study was designed to determine the implications of small airways inflammation in the development of airflow limitation in smokers by our newly explored method.	18930648
Presenile dementia, "Alzheimers Disease", Inflammation	Altered Intercellular Communication	Effects of gender and dementia severity on Alzheimer's disease caregivers' sleep and biomarkers of coagulation and inflammation.	18930805
Inflammation	Altered Intercellular Communication	To test the inflammation and immune activation hypothesis in primary thrombotic APS (PAPS) and to identify clinical and laboratory factors related to inflammation and immune activation.	18930964
Inflammation	Altered Intercellular Communication	Low-grade inflammation and immune activation occur in thrombotic PAPS and relate to clinical features and aPL levels.	18930964
vascular inflammations, Lupus Erythematosus	Altered Intercellular Communication	The Tie2 receptor antagonist angiopoietin 2 facilitates vascular inflammation in systemic lupus erythematosus.	18930996
Inflammation, Precocious atherosclerosis	Altered Intercellular Communication	Ang2 might facilitate endothelial inflammation, permeability and contribute to premature atherosclerosis.	18930996
Inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Strategies to control the deleterious effects of Ang2 may open new perspectives to prevent endothelial inflammation in SLE.	18930996
Inflammation, Obesity	Altered Intercellular Communication	Our findings suggest that offspring with a high risk of developing obesity have an altered biomarker profile, characterized by systemic inflammation and increased neurohormonal activity, even in the absence of obesity.	18931036
Airway structure, Sample Size Calculation, Lung Diseases, Interstitial, Systemic Scleroderma	Altered Intercellular Communication	To evaluate if IS may be a useful and safe tool for the detection of airway inflammation in patients with interstitial lung disease (ILD) in systemic sclerosis (SSc).	18931474
Sample Size Calculation	Altered Intercellular Communication	The IS method may allow a noninvasive assessment of cell composition in airway fluid and may contribute to the better understanding of upper/medium airway inflammation in SSc.	18931474
Sample Size Calculation, Pneumonitis	Altered Intercellular Communication	Future studies are needed to verify whether IS can replace invasive procedures for the detection and monitoring of lung inflammation in SSc.	18931474
Lichen - organism, Alopecia, CTCAE	Altered Intercellular Communication	Lichen planopilaris (LPP) is an inflammatory condition of unknown etiology that affects pilosebaceous units, mainly of the scalp, and results in scaring alopecia.	18931985
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The lesion was misdiagnosed at endoscopy as a malignancy, although histological examination of biopsies showed only chronic inflammation.	18936891
Inflammation, Heart failure	Altered Intercellular Communication	The results add to the concept that mood and autonomic unbalance are associated with increased systemic inflammation in old patients with decompensated CHF, a potential mechanism for mood-related worsened prognosis of heart failure at an advanced age.	18937152
Alzheimers Disease", Inflammation	Altered Intercellular Communication	Decreased expression of CD200 and CD200 receptor in Alzheimer's disease: a potential mechanism leading to chronic inflammation.	18938162
Inflammation	Altered Intercellular Communication	These observations have suggested that inflammation could be contributing to disease progression.	18938162
Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	Mechanisms aimed at increasing levels of CD200 and CD200R could have therapeutic potential for controlling inflammation in human neurodegenerative diseases.	18938162
Inflammation, Pneumonitis	Altered Intercellular Communication	They also demonstrated adjuvant effects of chitin in allergen-induced type 1 or type 2 inflammation and provided insights into the important roles of chitinases and chitinase-like proteins (C/CLP) in pulmonary inflammation.	18938241
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	I-type insulin-like growth factor receptor (IGF1R), hepatocyte growth factor receptor (HGFR), telomerase reverse transcriptase (TERT) and telomerase associated protein (TP-1) expression were evaluated immunohistochemically on biopsy specimens from 11 mild, 11 moderate and 12 severe active inflammation of UC cases and from 10 normal colonic tissue cases.	18938767
Inflammation	Altered Intercellular Communication	In mild inflammation, all observed parameters showed significantly elevated epithelial protein expression (IGF1R: 22.3 +/- 9.46%; HGFR: 35.3 +/- 22.8%; TERT/TP-1: 2.1 +/- 1.87%/2 +/- 1.32%) compared to normal (p < 0.005).	18938767
Inflammation	Altered Intercellular Communication	In moderately active inflammation, only IGF1R expression was significantly higher (50.2 +/- 8.6%) compared to normal and mild inflammation (p < 0.005).	18938767
Inflammation	Altered Intercellular Communication	In severe inflammation, all parameters showed decreased epithelial expression; IGF1R showed decreased mRNA expression, while HGFR was overexpressed and TERT showed a decreased tendency.	18938767
Gastroesophageal reflux disease, Inflammation	Altered Intercellular Communication	One potential unproved mechanism is that gastroesophageal reflux disease (GERD), in which acid reflux induces local and systemic inflammation, may increase triggered activity in the myocardium and pulmonary veins and increase AF risk.	18940293
Inflammation	Altered Intercellular Communication	Higher levels of inflammation are associated with adverse outcomes in patients with lower extremity peripheral arterial disease (PAD).	18940304
Inflammation, Neoplasms, Cyst	Altered Intercellular Communication	The study showed that the probability of clinical misdiagnosis of pathologically significant lesions associated with extracted teeth is lowest with inflammation and highest with cysts and neoplasms.	18940493
Inflammation, Primary angiitis of the central nervous system	Altered Intercellular Communication	Biopsies not diagnostic of PACNS (n=17, 37%) showed nonspecific gliosis (53%), mild perivascular mononuclear inflammation (18%), and parenchymal ischemic damage/infarct (18%).	18941399
Communicable Diseases, Ichthyosis Bullosa of Siemens, Inflammation	Altered Intercellular Communication	IBS probably is a cascade of many physiological events, being initiated by infection, inflammation, psychological disturbances-like many stresses and eventually leading to dysfunctions of gut and other systems of the body via a low-grade inflammatory process.	18942301
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Nevertheless, an inflammation of synovial membrane and a reduction of activity of articulation co-exist with rheumatoid arthritis.	18942334
Goiter, Hashimoto Disease, Have Autoimmune or Inflammatory Condition, "Sjogrens Syndrome", Dyspnea	Altered Intercellular Communication	A massively enlarging goitre, causing breathlessness in a female patient previously treated for autoimmune inflammation of the thyroid (Hashimoto's disease) and Sjogren's syndrome, indicated the need for a fine needle aspiration biopsy (FNA) of the thyroid gland.	18942337
Inflammation, Pouchitis	Altered Intercellular Communication	In active pouchitis, butyrate oxidation was significantly decreased compared with that in normal ileum and excluded pouches without inflammation.	18942762
Neurodegeneration due to 3-hydroxyisobutyryl coenzyme A hydrolase deficiency, Pouchitis	Altered Intercellular Communication	Active UC and pouchitis show the same inflammation-related metabolic defect.	18942762
Inflammation, Pouchitis	Altered Intercellular Communication	Our data suggest that the defect is a consequence of inflammation and that pouchitis is metabolically similar to active UC.	18942762
Inflammation, Thrombophilia, Tissue damage, Bulla, Thrombus	Altered Intercellular Communication	The hypercoagulability may contribute to inflammation, tissue damage, blister formation and possibly thrombotic risk in BP.	18945300
Inflammation, Injury of kidney, Kidney Diseases	Altered Intercellular Communication	These data provide the basis for studies that assess the contribution of polyclonal FLC to progressive renal injury and systemic inflammation in patients with kidney disease.	18945993
Inflammation, Metabolic Syndrome X, Cardiovascular Diseases	Altered Intercellular Communication	Metabolic syndrome is strongly associated with chronic subclinical inflammation in patients achieving optimal low-density lipoprotein-cholesterol levels in secondary prevention of cardiovascular disease.	18946171
Inflammation, Metabolic Syndrome X, Myocardial Ischemia, ETV3 wt Allele	Altered Intercellular Communication	This study sought to test the hypothesis that the metabolic syndrome (MetS) is associated with subclinical inflammation in patients achieving optimal LDL-C. A total of 227 Japanese subjects with a prior history of ischemic heart disease and optimal LDL-C (LDL-C <100 mg/dl) were enrolled.	18946171
Cervical lymphadenopathy	Altered Intercellular Communication	Recently I found a girl of 14 years old with gradual painless massive cervical lymphadenopathy for six weeks duration with no signs of acute inflammation.	18946460
Inflammation, Granulomatosis with polyangiitis, Granulomatous, Colitis, Ischemic	Altered Intercellular Communication	Orbito-ocular involvement in Wegener's granulomatosis is the result of both focal ischaemic vasculitis and granulomatous soft tissue inflammation.	18946592
Orbital Pseudotumor	Altered Intercellular Communication	Necrotising keratoscleritis and orbital inflammation are two most characteristic ophthalmic presentations.	18946592
Inflammation, Pseudomembrane	Altered Intercellular Communication	Blood tests detected an acute inflammation and colonoscopy revealed a massive inflammation of the bowel with pseudomembranes.	18946851
Inflammation	Altered Intercellular Communication	Extracellular superoxide dismutase (EC-SOD) is a potent antioxidant that plays an important role in controlling oxidant-mediated stress and inflammation.	18948423
Acute Lung Injury, Inflammation, Lung Injury	Altered Intercellular Communication	These results indicate that a GCCT haplotype may reduce inflammation in the lung, thereby decreasing the severity of lung injury and ultimately protecting patients from mortality associated with infection-induced ALI.	18948423
Pancreatitis, Fibrosis Assessment	Altered Intercellular Communication	This may be related to autoimmune mechanisms, serous membrane response, or the progression of pancreatic inflammation and fibrosis.	18948836
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Increased mast cell numbers in the conjunctiva of glaucoma patients: a possible indicator of preoperative glaucoma surgery inflammation.	18949008
Inflammation, Disorder of eye	Altered Intercellular Communication	Mast cells are important mediators of inflammation and scarring in allergic eye disease.	18949008
Inflammation	Altered Intercellular Communication	Patients infected with dupA-positive strains had higher scores for chronic inflammation compared to those with dupA-negative strains (2.36 vs. 2.24, p = 0.058).	18950522
Inflammation, Schistosoma hematobium infection	Altered Intercellular Communication	The seminal vesicles and the prostate are frequently affected by egg-induced inflammation in Schistosoma haematobium infected men.	18950598
Inflammation, Infiltration	Altered Intercellular Communication	This was further overlaid by prominent mononuclear inflammation, including infiltration by T lymphocytes, follicular aggregates of B cells, and attendant destruction of parenchyma.	18950959
Hypophysitis, CTCAE, Inflammation	Altered Intercellular Communication	By analogy, we hypothesize that this ectopic manifestation of immune-mediated inflammation of pituitary parenchyma may possibly be read as a preclinical sentinel lesion of lymphocytic hypophysitis.	18950959
Inflammation, Thrombosis, Brain Injuries, Cerebrovascular accident	Altered Intercellular Communication	Inflammation may play an important role in atherothrombosis and in promoting cerebral damage after stroke.	18952622
Inflammation, Spondylitis	Altered Intercellular Communication	Ankylosing spondylitis monocytes show upregulation of proteins involved in inflammation and the ubiquitin proteasome pathway.	18952638
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	[Changes of anaphylatoxin C5a in chronic obstructive pulmonary disease and the relationship with systemic and local inflammation].	18953960
Actual blood loss, Inflammatory disease of mucous membrane	Altered Intercellular Communication	In unilateral ESS cases, subjectively estimated blood loss and mucosal inflammation scores were lower in the no-packing group.	18954514
Inflammation	Altered Intercellular Communication	Bone remodeling of the paranasal sinuses can be affected by many factors including age, sex, chronic inflammation, and surgery.	18954517
Necrosis	Altered Intercellular Communication	Histologic parameters were similar among the 2 groups, including portal and lobular inflammation, piecemeal necrosis, and centrilobular necrosis.	18955163
Inflammation, Coronary Artery Disease, Heart Failure, Systolic	Altered Intercellular Communication	The role of inflammation--a key factor underlying coronary artery disease (CAD) and systolic heart failure--in promotion of left ventricular (LV) diastolic dysfunction has not been investigated extensively so far.	18955829
Inflammation, Impaired cognition	Altered Intercellular Communication	The inflammatory response to surgery is consistent with the hypothesis that inflammation contributes to cognitive decline in the elderly.	18955921
Inflammation, Epigastric pain	Altered Intercellular Communication	The authors describe the case of a 56 year old woman 25 days status post laparoscopic gastric bypass who presented with an acute onset of severe epigastric pain with signs of inflammation and localized peritoneal irritation.	18955934
Inflammation, Inflammatory Hepatocellular Adenoma, Hyperplasia	Altered Intercellular Communication	All nodules contained portal-like structures and ductular reaction, features seen in focal nodular hyperplasia, as well as significant inflammation, telangiectatic sinusoids and immunoreactivity for serum amyloid A, placing them according to a recently described classification systems as telangiectatic or inflammatory adenomas.	18956299
Inflammation, Diabetes Mellitus, Insulin-Dependent, Albuminuria, Endothelial dysfunction	Altered Intercellular Communication	YKL-40, a marker of inflammation and endothelial dysfunction, is elevated in patients with type 1 diabetes and increases with levels of albuminuria.	18957531
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	The inflammation marker YKL-40 is elevated in patients with type 2 diabetes and is associated with atherosclerosis and increased cardiovascular mortality.	18957531
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	Oxidative stress and inflammation are important pathogenetic mechanisms in amyotrophic lateral sclerosis (ALS).	18957896
Inflammation, Chronic purulent otitis media, Infection	Altered Intercellular Communication	Chronic suppurative inflammation of the middle ear (HGO) in children represents one of the most frequent infections in childhood, even in children from developed industrial countries.	18959168
Chronic suppurative inflammation, Cholesteatoma	Altered Intercellular Communication	We can distinguish two types of chronic suppurative inflammation: first--HGO without cholesteatoma and second HGO with cholesteatoma.	18959168
Otitis Media	Altered Intercellular Communication	From 2000 to 2005, our retrospective study involved 92 children, aged 2 to 16 years, treated for chronic suppurative inflammation of the middle ear and subsequent otogenic complications.	18959168
Bile Reflux, Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Role of bile reflux and Helicobacter pylori infection on inflammation of gastric remnant after distal gastrectomy.	18959592
Bile Reflux, Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The aim of this study was to investigate the role of bile reflux and Helicobacter pylori infection on endoscopic inflammation and histological changes of gastric remnant after distal gastrectomy.	18959592
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	The histological changes including chronic inflammation, activity, atrophy, intestinal metaplasia and H. pylori were evaluated independently.	18959592
Inflammation	Altered Intercellular Communication	An endoscopic inflammation of remnant gastric mucosae was found in 81.1% (228/281) of the patients.	18959592
Inflammation, Bile Reflux	Altered Intercellular Communication	The score of histological chronic inflammation was significantly higher in patients with bile reflux than in those without obvious bile reflux (1.65 vs 1.45, P = 0.02).	18959592
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	Chronic inflammation (1.82 vs 1.57), activity (0.78 vs 0.34), atrophy (0.67 vs 0.41) and intestinal metaplasia (0.67 vs 0.27) in H. pylori-positive patients were all significantly more severe than in H. pylori-negative patients.	18959592
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Bile reflux and H. pylori infection exacerbates the severity of endoscopic remnant gastritis and chronic histological inflammation.	18959592
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Correlation of serum biomarkers with clinical severity and mucosal inflammation in Chinese ulcerative colitis patients.	18959594
Inflammation	Altered Intercellular Communication	However, their role in predicting active mucosal inflammation on Chinese patients is unknown.	18959594
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Active mucosal inflammation was confirmed by colonoscopy and histology.	18959594
Inflammation	Altered Intercellular Communication	Routine serum biomarkers are not sensitive in predicting mucosal inflammation.	18959594
Inflammation, Reperfusion Injury	Altered Intercellular Communication	Reperfusion injury and inflammation associated with cardiac surgery are thought to be involved in its pathogenesis.	18959676
Inflammation, Ureteral obstruction, Aneurysm	Altered Intercellular Communication	Successful operative repair was performed with staged ureteral and endovascular stenting with subsequent resolution of periaortic inflammation and ureteral obstruction, and shrinkage of the aneurysm sac.	18971042
Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Increased urinary orosomucoid excretion: a proposed marker for inflammation and endothelial dysfunction in patients with type 2 diabetes.	18972260
Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Ventricular Dysfunction, Left	Altered Intercellular Communication	The aim of the present study was to determine whether increased UOER is associated with cardiovascular risk factors such as inflammation, impaired left ventricular function and endothelial dysfunction in patients with type 2 diabetes.	18972260
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Asymptomatic patients with type 2 diabetes and increased UOER displayed signs of chronic low-grade inflammation and endothelial dysfunction.	18972260
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The previously shown relation between increased UOER and cardiovascular mortality is proposed to be caused by chronic low-grade inflammation and early endothelial dysfunction.	18972260
Airway structure, Asthma	Altered Intercellular Communication	Vascular endothelial growth factor (VEGF) is a mediator of airway inflammation and remodeling in asthma.	18972287
Inflammation, Pharyngitis	Altered Intercellular Communication	Histological markers of inflammation were correlated with pharyngitis.	18972301
Crohn Disease, Acute inflammation	Altered Intercellular Communication	To retrospectively evaluate the efficacy of spectral presaturation attenuated inversion-recovery (SPAIR) fat-suppressed (FS) partial Fourier single shot (SSH) T2-weighted (T2W) and gadolinium-enhanced (Gd) FS 3D-gradient echo (3DGRE) T1-weighted (T1W) delayed phase MRI to differentiate active bowel inflammation from fibrotic disease in patients with Crohn's disease (CD).	18972354
Inflammation	Altered Intercellular Communication	Lymphoma of the testis and epididymis mimics chronic inflammation upon sonography.	18972362
Lymphoma, Chronic inflammation	Altered Intercellular Communication	We report the sonographic findings in a case of lymphoma, which mimicked chronic inflammation.	18972362
Inflammation, Ulceration, CTCAE, Granulation finding	Altered Intercellular Communication	Histology of the lesions showed marked acute and chronic inflammation consistent with ulceration and granulation tissue.	18972773
Inflammation, Dental Plaque	Altered Intercellular Communication	Increased plaque numbers were related to increased pocket depth irrespective of presence or absence of gingival inflammation.	18973540
Inflammation, neuron death, Data types - Address	Altered Intercellular Communication	Results presented here suggest that chronic neuronal TNF-alpha expression promotes inflammation and, ultimately, neuronal cell death in this AD mouse model, advocating the development of TNF-alpha-specific agents to subvert AD.	18974297
Inflammation, Choroidal Neovascularization	Altered Intercellular Communication	Although we found significant involvement of angiotensin II type 1 receptor (AT1-R)-mediated inflammation in choroidal neovascularization (CNV), a central abnormality of vision-threatening age-related macular degeneration, the association of receptor-associated prorenin system with CNV has not been defined.	18974301
Granulomatous inflammation	Altered Intercellular Communication	Patient suffered from chronic waxing and waning granulomatous inflammation with uncontrolled high intraocular pressure despite treatment.	18974522
Necrotizing granulomatous inflammation, Parasitic Diseases	Altered Intercellular Communication	Ocular parasitosis should be kept in mind as a differential diagnosis in treating non-responsive chronic hypertensive granulomatous inflammation, especially if the patient is of Southeast Asian origin or has recently visited the region.	18974522
Inflammation	Altered Intercellular Communication	Erythropoietin-stimulating agent (ESA) hyporesponsiveness is aggravated by chronic inflammation in maintenance hemodialysis (MHD) patients.	18974640
Inflammation	Altered Intercellular Communication	This improvement in ESA hyporesponsiveness is associated with the effects of statins on inflammation.	18974640
Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	Sex hormone status in young men differ from those in older men and may play an important role in the pathophysiology of IBS, regardless of the dominant symptom type.	18974649
Inflammation, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	We explored the relationship between anemia and markers of inflammation and endothelial activation in non-dialysis chronic kidney disease (ND-CKD) patients to understand this mechanism.	18974656
Inflammation, Trachoma	Altered Intercellular Communication	Furthermore, a subset of infected individuals develop inflammation and are at greater risk for developing the severe sequela of trachoma known as trachomatous trichiasis (TT).	18974840
Trachoma , Inflammation	Altered Intercellular Communication	While there are a number of environmental and behavioral risk factors for trachoma, genetic factors that influence inflammation and TT risk remain ill defined.	18974840
Abnormality of the skeletal system	Altered Intercellular Communication	FGF23 is a hormonal factor produced in bone and regulates serum levels of phosphate (Pi) and vitamin D. FGF23 over-expression is associated with skeletal abnormalities, including rickets/osteomalacia.	18974917
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Interleukin 6 (IL-6) is one of the mediators of inflammation in the neurodegenerative process in Alzheimer's disease (AD).	18975235
Inflammation, Ischemic, Cerebrovascular accident	Altered Intercellular Communication	Markers of inflammation were slightly higher in hyperthermic patients with ischaemic, but not with haemorrhagic stroke.	18975236
Inflammation	Altered Intercellular Communication	CXCL13 is a B cell chemoattractant that is instrumental in synovial B cell organization; the regulatory determinants of CXCL13 in inflammation are poorly characterized.	18975336
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	This study was undertaken to examine the effects of RhoA and its downstream effector Rho kinase (ROK) in synovial inflammation in rheumatoid arthritis (RA).	18975348
Inflammation, ASF1A gene	Altered Intercellular Communication	Intraperitoneal administration of fasudil in rats with CIA significantly reduced synovial inflammation and ROK activity.	18975348
Refractory anemias, Inflammation	Altered Intercellular Communication	The results of this study provide new evidence that blockade of ROK inhibits activation of NF-kappaB and production of proinflammatory cytokines, suggesting a critical role of ROK in the synovial inflammation of RA.	18975348
Inflammation	Altered Intercellular Communication	There was a hypocellular, loose, myxoid stromal matrix, with ectatic hyalinized vessels and mild to moderate chronic inflammation.	18976007
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	Low-grade systemic inflammation in patients with amyotrophic lateral sclerosis.	18976328
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	To prospectively determine the intensity of systemic low-grade inflammation in patients with amyotrophic lateral sclerosis (ALS).	18976328
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	A systemic low-grade inflammation was detected in patients with ALS and correlated with their degree of disability.	18976328
Inflammation, Hypertension, CTCAE, Cardiovascular Diseases, Hyperlipidemia	Altered Intercellular Communication	Risk factors of cardiovascular disease such as lipid aberrations, hypertension, abdominal adiposity and elevations in systemic inflammation, are prominent aetiologies in hyperlipidemia.	18977480
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor alpha (TNFalpha)-stimulated gene 6 (TSG-6) is involved in inflammation, extracellular matrix formation, cell migration, and development.	18979174
Inflammation	Altered Intercellular Communication	Agreement and correlation between immunoglobulin titers and inflammation markers were explored.	18979584
Inflammation	Altered Intercellular Communication	There was a correlation between inflammation markers, H pylori load, and immunoglobulin titers for IgG and IgA.	18979584
Inflammation, Hypertension, CTCAE, Ischemia	Altered Intercellular Communication	These changes may be associated with hypertension, inflammation, or ischemia, as well as altered brain function.	18979778
Inflammation	Altered Intercellular Communication	The relationship between the presence of tooth-borne subgingival deposits and inflammation found with a dental endoscope.	18980509
Inflammation, Calculi	Altered Intercellular Communication	A statistically significant relationship was found between deposits of subgingival calculus covered with biofilm and inflammation of the pocket wall, as measured by color change.	18980509
Inflammation, Calculi	Altered Intercellular Communication	In >60% of the cases, this inflammation was associated only with biofilm over deposits of calculus, not biofilm alone.	18980509
Inflammation, Calculi	Altered Intercellular Communication	Deposits of subgingival calculus covered with biofilm were directly related to >60% of pocket wall inflammation as measured by increased redness of the pocket epithelium.	18980509
Airway structure	Altered Intercellular Communication	Tracheostomy and related host-pathogen interaction are associated with airway inflammation as characterized by tracheal aspirate analysis.	18980836
Communicable Diseases, Inflammation	Altered Intercellular Communication	We analyzed cells and soluble mediators related to inflammation and/or infection.	18980836
Inflammation, Respiratory Failure	Altered Intercellular Communication	In conclusion tracheal aspirates presented high amounts of viable cells and soluble mediators independently to the cause of respiratory failure leading to tracheotomy and they represent suitable specimens to study infection/inflammation interactions.	18980836
vascular inflammations	Altered Intercellular Communication	Local vascular inflammation may be involved in atherogenesis, and influence the patency of vascular grafts.	18981595
Inflammation, Sarcoidosis, Pulmonary	Altered Intercellular Communication	Reduced pulmonary function is associated with enhanced inflammation and tissue inhibitor of metalloproteinase 1 concentration in the bronchoalveolar lavage fluid of patients with lung parenchymal sarcoidosis.	18981680
Inflammation, Sarcoidosis, Pulmonary	Altered Intercellular Communication	These results suggest that inflammation and enhanced TIMP-1 concentration in the lower airway play critical roles in the impaired pulmonary function in patients with lung parenchymal sarcoidosis.	18981680
Refractory anemias, Rheumatoid Arthritis, Inflammation, Hyperplasia	Altered Intercellular Communication	One of the hallmarks of rheumatoid arthritis (RA) is hyperplasia and inflammation of the synovial tissue being characterized by in situ occurrence of highly differentiated leukocytes.	18982072
Refractory anemias, Inflammation	Altered Intercellular Communication	Our findings indicate that Flt3-L is strongly expressed at the site of inflammation in human RA.	18982072
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Impact of cardiac rehabilitation on coronary risk factors, inflammation, and the metabolic syndrome in obese coronary patients.	18983328
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	This study sought to evaluate the association between systemic inflammation as measured by C-reactive protein and total joint replacement and the association between change in CRP status (low, < or = 10 mg/L and high, >10 mg/L) measured over one year and total joint replacement in patients diagnosed with rheumatoid arthritis.	18983663
Inflammation, Ewings sarcoma	Altered Intercellular Communication	Ewing sarcoma (ES) of the mandible is rare and can be mistaken for inflammation of dental origin.	18983686
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The airway inflammation of chronic obstructive pulmonary disease (COPD) demonstrates a poor response to the anti-inflammatory actions of corticosteroids.	18983928
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Epicardial adipose tissue as a source of nuclear factor-kappaB and c-Jun N-terminal kinase mediated inflammation in patients with coronary artery disease.	18984670
Inflammation	Altered Intercellular Communication	Epicardial AT from patients with CAD shows increased NFkappaB, IKKbeta, and JNK expression compared with both CAD thigh AT and non-CAD epicardial AT, suggesting a depot-specific as well as a disease-linked response to inflammation.	18984670
Inflammation	Altered Intercellular Communication	These studies implicate both NFkappaB and JNK pathways in the inflammatory profile of epicardial AT and highlight the role of the macrophage in the inflammation within this tissue.	18984670
Inflammation, Stomach Carcinoma, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Helicobacter pylori infection is related to gastric cancer development, and chronic inflammation is presumed to be the main cause.	18985541
Inflammation, Traumatic injury, Immune System Diseases	Altered Intercellular Communication	Immune dysfunction in trauma patients is associated with immune system activation and inflammation.	18986303
Inflammation, Gangrene	Altered Intercellular Communication	Inflammation and gangrene was found in the small intestine.	18986622
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) is characterized by persistent mucosal inflammation and frequent exacerbations.	18986692
Virus Diseases, Craniosynostosis, exacerbation acute, Eosinophilic inflammation	Altered Intercellular Communication	We propose that an analogous response to cigarette smoke plus viral infection may contribute to acute exacerbations and eosinophilic mucosal inflammation in CRS.	18986692
Liver parenchyma, Inflammation, FAM126A gene	Altered Intercellular Communication	The factors affecting patient survival after lip-TACE were microscopic portal venous involvement of HCC at liver resection, grade of inflammation in the noncancerous liver parenchyma, and recurrence within 1 year after the initial liver resection.	18987934
Conjunctival irritation	Altered Intercellular Communication	No eyelid inflammation, lacrimation, or palpebral or bulbar conjunctival irritation was observed in human eye instillation studies.	18988091
Retinal Detachment, Inflammation	Altered Intercellular Communication	Ten days later, as the inflammation subsided, a retinal detachment caused by a macular hole was diagnosed.	18988182
Hypoxemia, Inflammation, Sleep Apnea, CTCAE, Steatohepatitis	Altered Intercellular Communication	To examine whether sleep apnea and nocturnal hypoxemia predict the severity of insulin resistance, systemic inflammation, and steatohepatitis in severely obese individuals presenting for bariatric surgery.	18990675
Oxygen saturation below reference range, Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	Histopathology data suggested that significant nocturnal desaturation might predispose to hepatic inflammation, hepatocyte ballooning, and liver fibrosis.	18990675
Inflammation	Altered Intercellular Communication	TNF signaling activates the nuclear factor-kappaB (NF-kappaB) canonical pathway, leading to transcriptional activation of multiple genes that influence inflammation and immune response.	18990758
Macular Edema, Cystoid, Intraocular inflammation	Altered Intercellular Communication	Efficacy and complications of intravitreal injection of triamcinolone acetonide for refractory cystoid macular edema associated with intraocular inflammation.	18991038
Intraocular inflammation	Altered Intercellular Communication	IVTA is effective for PSTA-resistant CME with intraocular inflammation, and its efficacy might be dose dependent.	18991038
Sepsis, Inflammation, Communicable Diseases	Altered Intercellular Communication	Sepsis is defined as systemic inflammation caused by infection.	18991094
Pain Distress Question, Inflammation, Ulcer	Altered Intercellular Communication	Numerous treatments have been tried as a means of relieving pain, disinfecting the ulcer base, and reducing inflammation, but with limited success.	18991147
Inflammation, Intrasynovial Route of Drug Administration, Tenosynovitis	Altered Intercellular Communication	The massive tenosynovitis and adhesion of flexors tendons after the locking of the intrasynovial lipoma may have resulted from inflammation caused by attrition within the carpal tunnel.	18991179
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Inflammation and genetics play an important role in the pathogenesis of coronary heart disease (CHD).	18991687
Inflammation	Altered Intercellular Communication	The fine balance between inflammation and antiinflammation, as well as the role of humoral immune response either systemic or mucosal will be discussed as a consequence of red wine intake.	18991693
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The identification of CRC-predisposing combinations, composed of alleles PTGS1 c.639A, PLA2G2A c.435+230C, PPARG c.1431C, IL8 c.-352A, and MTHFR c.1286C, highlights the importance of inflammatory processes in susceptibility to sporadic CRC, as well as a possible crosstalk between inflammation and one-carbon pathways.	18992148
Malignant tumor of colon, Inflammation	Altered Intercellular Communication	The important modifying effects of aspirin/NSAIDs on associations with genetic polymorphisms reinforce the underlying role of inflammation in the etiology of colon cancer.	18992263
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Retroperitoneal fibrosis is characterized by the presence of a retroperitoneal tissue, consisting of chronic inflammation and marked fibrosis, which entraps the retroperitoneal organs.	18995843
Lofgrens syndrome, Fever, CTCAE, Hilar lymphadenopathy, Arthritis, Orchitis, Erythema Nodosum	Altered Intercellular Communication	Patients with Lofgren's syndrome have an acute onset of erythema nodosum (EN) and/or periarticular inflammation or arthritis of the ankles, with bilateral hilar lymphadenopathy (and in some cases parenchymal infiltrates) and usually fever.	18996998
Inflammation, Atherosclerosis	Altered Intercellular Communication	Adiponectin and resistin, which have counteracting effects, are suggested to be associated with inflammation and atherosclerosis.	18997620
Inflammation, Pancreatitis, Pseudoaneurysm	Altered Intercellular Communication	The majority of them are false or pseudoaneurysms, often seen in the setting of inflammation, specifically with pancreatitis.	19000986
Bronchitis	Altered Intercellular Communication	We investigated the anti-inflammatory potential of n-3 polyunsaturated fatty acids (PUFA) on specific bronchial inflammation.	19001792
Bronchitis	Altered Intercellular Communication	Our results provide evidence that dietary supplementation with n-3 PUFA is able to reduce bronchial inflammation even after low-dose allergen challenge.	19001792
Acute and chronic inflammation, Diabetes Mellitus	Altered Intercellular Communication	Recent histological analysis of pancreases obtained from patients with long-standing type 1 diabetes identified chronic islet inflammation and limited evidence suggestive of beta cell replication.	19002428
Inflammation	Altered Intercellular Communication	We therefore tested the hypothesis that beta cell replication is observed in non-autoimmune human pancreatic disorders in which localised inflammation or elevated gastrin levels are present.	19002428
Pancreatitis	Altered Intercellular Communication	These findings indicate that chronic severe pancreatic inflammation can be associated with significant effects on beta cell number or replication rate, depending on the distribution of the cells.	19002428
Gastrointestinal inflammation	Altered Intercellular Communication	Recurrent abdominal symptoms lead to ultrasonography showing intestinal inflammation.	19002546
Myocardial rupture, Myocarditis, Tissue Adhesions	Altered Intercellular Communication	Pericardial adhesions or slow extracardiac leak and pericardial inflammation may result in a contained cardiac rupture.	19004078
Inflammation	Altered Intercellular Communication	The presence of mixed (aerobic and anaerobic) microflora in the inflammation center has been marked recently.	19004254
Parathyroid Adenoma, Hyperparathyroidism, Primary, Malignant Neoplasms	Altered Intercellular Communication	Further evaluation demonstrated that the patient had primary hyperparathyroidism due to a parathyroid adenoma, as well as an increased parathyroid hormone-related peptide secondary to her malignancy.	19005452
Inflammation, Abscess, Vasogenic Edema	Altered Intercellular Communication	The magnetic resonance image was consistent with right parietal perisulcal pial and superficial cortical inflammation; a subjacent vasogenic edema with a 1 cm diameter abscess was also present.	19005460
Microabscess, Subarachnoid Hemorrhage, Retinitis, Meningitis, Cryptococcal	Altered Intercellular Communication	He was diagnosed with pseudosubarachnoid hemorrhage secondary to cryptococcal meningitis and choroidal microabscesses with retinal inflammation after a cerebrospinal fluid (CSF) examination revealed cryptococcal yeast forms, as well as high titers of CSF cryptococcal antigen, but no CSF red blood cells.	19005460
Cancer of Nose	Altered Intercellular Communication	Sinonasal cancers often masquerade as chronic inflammatory conditions of the upper respiratory tract, and thus they may progress unrecognized and untreated.	19006053
Inflammation, Data types - Address	Altered Intercellular Communication	Inflammation plays a key role in AD and dissecting the genetics of inflammation may provide an answer to the possible treatment.	19006850
Inflammation, Data types - Address	Altered Intercellular Communication	However, our results showing the involvement of TLR4 in AD pathophysiology, strengthen the suggestion that systemic inflammation plays a key role in AD.	19006850
Inflammation, Impaired cognition, Data types - Address	Altered Intercellular Communication	Carriers of high responder SNP, affected by mild cognitive impairment might, be the ideal target for a preventive treatment with biologics as monoclonal antibodies directed against the pro-inflammatory cytokines to decrease the level of systemic inflammation involved in AD pathophysiology.	19006850
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Characterisation of Interleukin-8 and monocyte chemoattractant protein-1 expression within the abdominal aortic aneurysm and their association with mural inflammation.	19008128
Inflammation, Glucocorticoid deficiency with achalasia, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Abdominal aortic aneurysms (AAAs) are characterised by chronic transmural inflammation.	19008128
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	AS is characterized by distinct upregulation of ET-1 and its target receptor ET(A), promoting growth, inflammation, and fibrosis.	19008257
Inflammation, Thrombophilia	Altered Intercellular Communication	In conclusion, activation of inflammation and tendency to hypercoagulation is observed in preoperative plasma and synovia of patients undergoing TKA surgery.	19009338
Inflammation	Altered Intercellular Communication	Cross-linking of LILRA5 on monocytes induced production of pro-inflammatory cytokines, suggesting that LILRA5 plays a role in inflammation.	19009525
Pneumonitis	Altered Intercellular Communication	Exhaled nitric oxide (NO) concentration is a marker of pulmonary inflammation.	19009623
Fasciitis, Necrosis with inflammation	Altered Intercellular Communication	Perineal necrotising fasciitis is a fast advancing necrotic inflammation in the soft tissue of the perineal and perianal spaces and in the genital area sometimes involving even the abdominal wall and the two hips.	19009749
Inflammation, Necrosis	Altered Intercellular Communication	The inflammation was diffuse; in three patients (27.27 +/- 13.43%) we found production of gas in the inflamed subcutaneous tissues, with crepitations and fast progressing skin necrosis.	19009749
Inflammation	Altered Intercellular Communication	At this stable weight he had a large surplus of abdominal wall skin with functional hindrance and inflammation due to chafing.	19009812
Inflammation, Asthma, Obesity, Impaired lung function	Altered Intercellular Communication	The findings show that higher levels of C-reactive protein in young adults are associated with subsequent decline in lung function, suggesting that low-grade systemic inflammation in young adulthood may lead to impaired lung function independently of the effects of smoking, obesity, cardiorespiratory fitness, asthma and eosinophilic inflammation.	19010993
Sepsis, Inflammation, Communicable Diseases, Community-Acquired Infections	Altered Intercellular Communication	This effect was not seen with plasma from patients with community-acquired infections who did not develop sepsis, nor with plasma from patients with acute or chronic inflammation who had no evidence of infection.	19011162
Inflammation, Atherosclerosis	Altered Intercellular Communication	Of all risk factors for CVD, smoking is most associated with the development of inflammation and accelerated atherosclerosis due to a prooxidant-antioxidant imbalance.	19011671
Inflammation, Hypoxia, cell injury	Altered Intercellular Communication	EC exhibited higher expression levels of markers of oxidative stress (lipid peroxydation level and caveolin-1 mRNA), inflammation (angiopoietin-like 2 mRNA), hypoxia (vascular endothelial growth factor (VEGF)-A mRNA), and cell damage (p53 mRNA).	19011671
Degenerative polyarthritis, Inflammation, Metabolic Diseases, Obesity	Altered Intercellular Communication	Our findings indicate that obesity and inflammation are related to osteoarthritis, a metabolic disease affected by microRNA deregulation.	19011694
Inflammation, Headache, Frontotemporal, Osteolysis	Altered Intercellular Communication	Headache of a diagnosis: frontotemporal pain and inflammation associated with osteolysis.	19012561
Inflammation, Dysplasia, Villous atrophy, Metaplasia, Ulceration, CTCAE	Altered Intercellular Communication	Confocal images were scored for the presence of villous atrophy, inflammation, ulceration, colonic metaplasia and dysplasia.	19013113
Inflammation, Metaplasia, Villous atrophy	Altered Intercellular Communication	At endomicroscopy, pathological features were found in 16/18 (88.9%), villous atrophy in 15/18 (83.3%), inflammation in 13/18 (72.2%), ulceration in 3/18 (16.7%), and colonic metaplasia in 12/18 (67.7%).	19013113
Inflammation, Metaplasia, Villous atrophy	Altered Intercellular Communication	At histology, abnormalities were present in 17/18 (94.4%): villous atrophy in 15/18 (83.3%), inflammation in 17/18 (94.4%), ulceration in 6/18 (33.3%), colonic metaplasia in 15/18 (83.3%).	19013113
Autoimmune Diseases, Orbital Pseudotumor	Altered Intercellular Communication	Thyroid-Associated Orbitopathy (TAO) is an autoimmune disease characterized by orbital inflammation involving both adipose tissue and extra-ocular muscles (EOM).	19013383
Chronic heart failure, Anemia, Inflammation Mediators	Altered Intercellular Communication	Anaemia as an inflammation-mediated condition during chronic heart failure.	19013998
Inflammation	Altered Intercellular Communication	Early studies suggested a pathogenic role of inflammation mediators.	19013998
Inflammation, Heart failure, Anemia, Congestive heart failure	Altered Intercellular Communication	Anaemia is common in CHF patients and it is associated with heart failure severity.The increase of fibrinogen plasma levels in CHF patients seems to confirm that chronic inflammation is involved in the pathogenesis of anaemia.	19013998
Inflammation	Altered Intercellular Communication	The likely mechanism of action is its recognized ability to stimulate angiogenesis and reepithelialization and to inhibit inflammation.	19015423
HD Term Type, Inflammation, Atherosclerosis	Altered Intercellular Communication	The results indicate that atherosclerosis in HD patients correlates with some nontraditional risk factors--the markers of inflammation.	19016154
Inflammation, Inflammatory disorder	Altered Intercellular Communication	REG Ialpha protein is known to be overexpressed not only in various human inflammatory diseases but also in various experimental models of inflammation in animal tissues.	19016805
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Blood was taken at the end of each 3-day block for assays of markers of endothelial activation, inflammation and coagulation.	19017697
Inflammation	Altered Intercellular Communication	Neutrophils undergo phenotypic and functional changes under inflammatory conditions, but the mechanisms regulating CR expression of infiltrated neutrophils at sites of chronic inflammation are poorly defined.	19017998
Inflammation	Altered Intercellular Communication	Neutrophils undergo phenotypic and functional changes under inflammatory conditions, but the mechanisms regulating CR expression of infiltrated neutrophils at sites of chronic inflammation are poorly defined.	19017998
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	TM7 bacteria might play an important role in IBD similar to that previously described in oral inflammation.	19018031
Lymphedema	Altered Intercellular Communication	Adjusted odds ratios for the development of lymphedema were 3.80 (95% confidence interval [CI] = 1.84-7.87) for previous inflammation-infection and 1.06 (95% CI = 1.02-1.10) for an increase of 1 year of age at axillary dissection.	19018216
Lymphedema	Altered Intercellular Communication	Previous inflammation-infection and advanced age at axillary dissection are risk factors associated with the initiation of lymphedema.	19018216
Lymphedema, Obesity	Altered Intercellular Communication	Previous inflammation-infection, operation on the side of the dominant hand, obesity, and aging are potential risk factors associated with the aggravation of lymphedema.	19018216
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Although the likelihood of intermediate alpha-1-antitrypsin deficiency (PiMZ) patients developing chronic obstructive pulmonary disease (COPD) remains uncertain, several investigators have suggested that a lack of antiprotease inhibitor activity may favour the development of airway inflammation with subsequent pulmonary tissue damage.	19019191
Airway structure, Lung Diseases, Obstructive	Altered Intercellular Communication	Such findings seem to suggest the importance of FeNO measurements on PiMZ subjects for monitoring a possible progression of airway inflammation to obstructive lung disease as observed in some of these patients.	19019191
Fatty Liver, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Adiponectin inhibits steatotic CD95/Fas up-regulation by hepatocytes: therapeutic implications for hepatitis C. Steatosis may trigger hepatocytes to up-regulate CD95/Fas thereby increasing susceptibility to apoptosis, inflammation and fibrosis.	19019483
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Hepatocyte CD95/Fas up-regulation correlated with steatosis, inflammation and fibrosis (p = .004).	19019483
Fatty degeneration	Altered Intercellular Communication	Liver adiponectin correlated with steatosis (p = .016), CD95/Fas (p < .001) and inflammation/fibrosis.	19019483
Inflammation, Fibrosis Assessment, Fatty degeneration, Hepatitis C	Altered Intercellular Communication	In chronic HCV infection, steatosis up-regulates hepatocyte CD95/Fas and thus increases apoptosis, which facilitates inflammation and fibrosis.	19019483
Inflammation, Malnutrition	Altered Intercellular Communication	Serum lipids and neopterin in urine as new biomarkers of malnutrition and inflammation in the elderly.	19019628
Inflammation, Malnutrition	Altered Intercellular Communication	Levels of serum lipids are influenced by malnutrition and inflammation.	19019628
Inflammation, Malnutrition	Altered Intercellular Communication	Total cholesterol, HDL, and LDL can be considered novel biomarkers of malnutrition and inflammation in geriatric patients.	19019628
Synovitis, Inflammation, Tenosynovitis, Edema of bone marrow	Altered Intercellular Communication	MRI synovitis (SRM between -0.79 and -0.92) and the MRI total inflammation score comprising synovitis, tenosynovitis and bone marrow oedema (SRM between -1.05 and -1.24) were highly responsive.	19019893
Inflammation, Sacroiliac joint structure, Fibrosis Assessment	Altered Intercellular Communication	Inflammation progresses to fibrosis and calcification of the spine and sacroiliac joints in AS development.	19019896
Inflammation, Hemorrhage, Pterygium Of Conjunctiva And Cornea	Altered Intercellular Communication	To compare the degree of conjunctival autograft inflammation, subconjunctival haemorrhage (SCH) and graft stability following the use of sutures or fibrin glue (FG) during pterygium surgery.	19019930
Inflammation	Altered Intercellular Communication	No significant difference was found for inflammation at 1 week postoperatively (p = 0.518).	19019930
Inflammation, Pterygium Of Conjunctiva And Cornea	Altered Intercellular Communication	This is the first prospective clinical trial confirming that conjunctival grafts secured with FG during pterygium surgery not only are as stable as those secured with sutures, but also produce significantly less inflammation.	19019930
Inflammation	Altered Intercellular Communication	In at least two episodes, the intracranial portion of the optic nerve showed significant inflammation on magnetic resonance imaging.	19021599
Inflammation, Chronic Kidney Diseases, Vascular calcification	Altered Intercellular Communication	Chronic inflammation, which is common in CKD, may promote vascular calcification.	19021697
HD Term Type, Inflammation	Altered Intercellular Communication	We investigated the impact of inflammation on the relationship between serum fetuin-A and mortality (42 months) in 222 prevalent haemodialysis (HD) patients.	19021697
HD Term Type, Inflammation	Altered Intercellular Communication	The results show that low levels of serum fetuin-A are associated with increased mortality in HD patients only in the presence of inflammation.	19021697
Cessation of life, Inflammation, HD Term Type	Altered Intercellular Communication	This suggests that coexistence of a low serum fetuin-A level and low-grade inflammation exerts an additive effect on the risk of death in HD patients.	19021697
Inflammation, atherosclerotic	Altered Intercellular Communication	Several studies have shown the presence of a broad spectrum of bacterial species in atherosclerotic plaques, which could trigger local inflammation.	19021704
Dental Plaque, Plaque, Atherosclerotic	Altered Intercellular Communication	Because T cells contribute to atherosclerotic plaque inflammation, we studied the responsiveness of human plaque derived T-cell cultures to bacteria of different species.	19021704
Inflammation, Destruction (action)	Altered Intercellular Communication	This form is characterized by inflammation, neuronal destruction, and organ dilatation.	19022313
Inflammation	Altered Intercellular Communication	Our data support the hypothesis that both enzymes play a crucial role in inflammation by affecting local tissue ratios between active and inactive glucocorticoids.	19022342
Communicable Diseases, Dermatitis	Altered Intercellular Communication	As exemplified by the case reports, it may take a particularly severe course and require treatment of both infection and skin inflammation.	19022534
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Chronic low-grade inflammation has been associated with insulin resistance and type 2 diabetes.	19022962
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Therefore, these results show that CP can lower hsCRP, a marker of inflammation associated with insulin resistance and type 2 diabetes.	19022962
Inflammation	Altered Intercellular Communication	Our primary objective was to evaluate the extent to which adiposity and pathogenicity contribute to a double burden of inflammation in a population currently undergoing the nutrition transition.	19022970
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	These results underscore the need for additional research on the contributions of pathogenicity, adiposity, and inflammation to global epidemics of cardiovascular and metabolic diseases.	19022970
Inflammation	Altered Intercellular Communication	Heart rate variability (HRV) is reduced in several clinical settings associated with either systemic inflammation or neuropsychiatric impairment.	19023029
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The interaction between inflammatory cytokines and endothelial cells is a critical step in atherogenesis leading to endothelial dysfunction and inflammation.	19023130
Tumor necrosis, vascular inflammations	Altered Intercellular Communication	We have previously reported that the tumor necrosis factor superfamily member LIGHT could be involved in atherogenesis through its ability to promote vascular inflammation.	19023130
Pleurisy	Altered Intercellular Communication	These findings suggest that pleural IL-6 levels correlate with local lung or pleural inflammation in patients admitted to the ICU.	19023164
Kidney Failure, Chronic, Inflammation, Malnutrition, Pulmonary Dysfunction	Altered Intercellular Communication	Pulmonary dysfunction is possibly a marker of malnutrition and inflammation but not mortality in patients with end-stage renal disease.	19023220
Inflammation, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	Various studies have indicated that malnutrition and chronic inflammation are strong predictors of morbidity and mortality in patients with chronic kidney disease (CKD).	19023220
Inflammation, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	The purpose of this study was to investigate the relationship between pulmonary function, malnutrition and chronic inflammation in patients with CKD.	19023220
Inflammation, Malnutrition	Altered Intercellular Communication	Impaired pulmonary function was associated with malnutrition and inflammation in these dialysis patients.	19023220
Inflammation, Pain Distress Question, Specimen Type - Fistula, Induration, Perianal disease	Altered Intercellular Communication	Perianal disease was considered active in the presence of visible fistula drainage and/or signs of local inflammation (induration and pain at digital compression) upon clinical examination.	19023861
Arthritis	Altered Intercellular Communication	Similar clinical features are reported in the literature in patients with chronic joint inflammation treated with low-dose methotrexate.	19024069
Kidney Diseases, Ischemia of kidney, Nephritis	Altered Intercellular Communication	It appears that the most probable pathway for the development of BKV nephropathy requires a second hit, such as kidney inflammation, kidney ischemia, or donor-recipient human leukocyte antigen mismatch.	19025923
Periodontal Diseases, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Periodontal disease has been associated with cardiovascular disease (CVD), and inflammation may represent a common pathophysiology.	19026305
Inflammation, Periodontal Diseases	Altered Intercellular Communication	In conclusion, self-reported periodontal disease is independently associated with inflammation and common in individuals without traditional CVD risk factors.	19026305
Intraocular inflammation, Ocular Toxoplasmosis	Altered Intercellular Communication	Intraocular inflammation associated with ocular toxoplasmosis: relationships at initial examination.	19027421
Intraocular inflammation, Inflammation, Ocular Toxoplasmosis	Altered Intercellular Communication	To describe characteristics of intraocular inflammation in eyes with active ocular toxoplasmosis and to identify relationships between signs of inflammation, complications (including elevated intraocular pressure [IOP]), other disease features, and host characteristics.	19027421
Inflammation, Corneal Opacity, Vitreous body structure	Altered Intercellular Communication	Signs of inflammation included anterior chamber (AC) cells and flare and vitreous humor cells and haze.	19027421
Inflammation, Lesion of retina	Altered Intercellular Communication	One or more signs of increased inflammation were related to the following factors: older patient age, larger retinal lesions, and extramacular location.	19027421
Intraocular inflammation, Ocular Toxoplasmosis	Altered Intercellular Communication	There is substantial variation between patients in the severity of intraocular inflammation associated with ocular toxoplasmosis, attributable to multiple host- and disease-related factors.	19027421
Disability, Inflammation	Altered Intercellular Communication	The frailty syndrome is characterized by chronic inflammation, decreased functional and physiologic reserve, and increased vulnerability to stressors, leading to disability and mortality.	19027777
Inflammation	Altered Intercellular Communication	However, molecular mechanisms that contribute to inflammation activation and regulation in frail older adults have not been investigated.	19027777
Inflammation	Altered Intercellular Communication	Histological severity of the disease was assessed to quantify the ileal inflammation.	19027918
Inflammation	Altered Intercellular Communication	Histological inflammation was moderately severe in the diseased bowel, while it was absent in healthy segments (P < 0.01).	19027918
Inflammation	Altered Intercellular Communication	Plaque instability is recognized as a multivessel phenomenon related to inflammation.	19028065
Inflammation	Altered Intercellular Communication	Activin A, a member of the transforming growth factor-beta cytokine family, has been suggested to have a role in inflammation.	19028479
Inflammation, Malnutrition	Altered Intercellular Communication	Association of environmental cadmium exposure with inflammation and malnutrition in maintenance haemodialysis patients.	19028751
Inflammation, Malnutrition, Chronic Kidney Diseases, Cardiovascular system	Altered Intercellular Communication	Chronic inflammation and malnutrition are associated with increased risk of cardiovascular death, and may cause protein-energy wasting in individuals with chronic kidney disease.	19028751
Inflammation, Malnutrition	Altered Intercellular Communication	However, the correlation of Cd exposure with inflammation and malnutrition remains uncertain.	19028751
Malnutrition, HD Term Type, Inflammation	Altered Intercellular Communication	Environmental Cd exposure is significantly associated with malnutrition, inflammation and even protein-energy wasting in maintenance HD patients.	19028751
Ischemic stroke	Altered Intercellular Communication	Single-nucleotide polymorphisms (SNPs) in inflammation-related genes have been linked to an increased risk of ischemic stroke.	19028820
Inflammation, Damage	Altered Intercellular Communication	The minimized extracorporeal circulation system causes less inflammation and organ damage.	19029264
Inflammation, AHSG protein, human	Altered Intercellular Communication	Fetuin-A, a protein almost exclusively secreted by the liver, induces insulin resistance and subclinical inflammation in rodents.	19029462
Hypochlorhydria, Carcinogenesis, Inflammation	Altered Intercellular Communication	As both inflammation and hypochlorhydria, which might facilitate proximal colonization of H. pylori and other bacterial species alike, have been implicated in gastric carcinogenesis, much attention has been directed to functional genetic polymorphisms that affect the production of IL-1 beta.	19031173
Airway structure, ARCN1 gene	Altered Intercellular Communication	HNP1-3 may be involved in the pathogenesis of airway inflammation in COPD.	19031798
Inflammation, Fever, CTCAE	Altered Intercellular Communication	The diagnostic utility of procalcitonin (PCT) and C-reactive protein (CRP) to discriminate between infective fever and fever due to inflammation was assessed in hemato-oncological patients treated with aggressive chemotherapy.	19031957
Eosinophilic esophagitis, Feeding difficulties	Altered Intercellular Communication	Eosinophilic esophagitis (EE), a rare chronic inflammatory condition of the esophagus, is predominantly observed in children and is primarily manifested with feeding difficulties.	19032119
Inflammation	Altered Intercellular Communication	C-reactive protein (CRP) is a marker of systemic low-grade inflammation, and may be associated with subjective symptoms of androgen deficiency.	19032692
Inflammation	Altered Intercellular Communication	Low-grade inflammation may be involved in the pathogenesis of subjective symptoms of androgen deficiency in ageing men.	19032692
Refractory anemias, Inflammation	Altered Intercellular Communication	These data suggest that another look at the role of ESR and CRP as markers of inflammation in RA patients seen in routine care may be in order.	19032813
Inflammation, Arthritis	Altered Intercellular Communication	Serum soluble CD30 in early arthritis: a sign of inflammation but not a predictor of outcome.	19032830
Inflammation, SLC25A20 gene, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Although perceived r/e discrimination is associated with certain health characteristics that may result in negative health outcomes, in general, we found no association of r/e discrimination with either subclinical atherosclerosis as determined by CAC score, aortic wall thickness and aortic plaque area, or inflammation as assessed by elevated CRP levels.	19033005
Inflammation	Altered Intercellular Communication	No relevant changes were observed for FMD or biomarkers of oxidative stress and inflammation.	19033020
Intraocular inflammation	Altered Intercellular Communication	Characteristics of severe intraocular inflammation following intravitreal injection of bevacizumab (Avastin).	19033289
Intraocular inflammation, Endophthalmitis, CTCAE, Eye Hemorrhage	Altered Intercellular Communication	This procedure is performed on a rapidly increasing number worldwide, and rare complications such as intraocular inflammation, endophthalmitis or intraocular haemorrhage are gaining in importance in clinical routine.	19033289
Intraocular inflammation	Altered Intercellular Communication	This is a single-centre retrospective interventional case series of eight patients with severe intraocular inflammation after intravitreal injection of bevacizumab at one referral centre consecutively seen out of approximately a total of 2500 injections performed in that time period.	19033289
Inflammation, Painless	Altered Intercellular Communication	Characteristic features of an inflammation induced by bevacizumab injection include an early onset with painless loss in VA mostly without conjunctival or ciliary injection.	19033289
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Markers of hemostasis and inflammation such as plasminogen activator inhibitor-1 (PAI-1) and fibrinogen have been associated with risk of type 2 diabetes.	19033409
Inflammation, Dental Plaque	Altered Intercellular Communication	Recent studies revealed that inflammation contributes to plaque instability.	19033684
Inflammation	Altered Intercellular Communication	Cyclo-oxygenase (COX)-2 is one of the key enzymes in plaque inflammation.	19033684
Follicular hyperplasia, Inflammation, Thickened, Granuloma	Altered Intercellular Communication	Capsular thickening and inflammation (6/9), venulitis (3/9), small granulomas (3/9), and follicular hyperplasia (7/9) were observed in the associated lymphoid parenchyma.	19033867
Arthritis	Altered Intercellular Communication	Several studies suggest that IL-23 is an essential promoter of chronic joint inflammation.	19034457
Acute inflammation, Traumatic injury	Altered Intercellular Communication	However, MICS does not reduce surgical trauma and postoperative inflammation as compared to conventional SICS.	19035244
Symptomatic, Inflammation, Degenerative polyarthritis, Pain Distress Question	Altered Intercellular Communication	Symptomatic joints were significantly more likely to demonstrate US-detected structural changes or inflammation in symptomatic hand OA; however, the extent of changes in individual joints or in individuals did not correlate with the degree of symptoms, which may relate to both the assessment tools and the complex nature of pain.	19035429
Refractory anemias, Inflammation, destruction joint	Altered Intercellular Communication	Our findings of high expression of TLRs, particularly TLRs 3 and 4, at an early stage of RA and the reactivity of synovial fibroblasts in vitro to TLR ligands suggest that TLR signaling pathways resulting in persistent inflammation and joint destruction are activated early in the disease process.	19035519
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Since chronic inflammation is associated with tissue remodeling in inflammatory bowel disease (IBD), we evaluated serum TIMP-1 and TIMP-4 levels in IBD patients, in comparison with healthy controls (HC).	19036126
Inflammation, Pulmonary Embolism	Altered Intercellular Communication	Gas6 protein is involved in pulmonary embolism (PE) and acute inflammation in animal models.	19036570
Inflammation	Altered Intercellular Communication	The data link Gas6 protein to infection/inflammation, but not to PE, in humans.	19036570
Xanthogranulomatous inflammation	Altered Intercellular Communication	The cystic mass and one ill-defined solid mass were pathologically-proven to be xanthogranulomatous inflammation.	19037562
Adenocarcinoma, Inflammation	Altered Intercellular Communication	The other five solid masses were found to be adenocarcinoma in three and chronic non-specific inflammation in two cases.	19037562
Inflammation, Lymphoid hyperplasia, Lymphoma, Actinomycosis	Altered Intercellular Communication	In the pediatric group only one case was diagnosed as lymphoma (0.13%) and the rest as chronic inflammation (47%), reactive tonsil tissue (26%), lymphoid hyperplasia (19%) and actinomycosis (8%).	19037653
Inflammation	Altered Intercellular Communication	Nitric oxide attenuates vascular endothelial cadherin-mediated vascular integrity in human chronic inflammation.	19037921
Inflammation	Altered Intercellular Communication	These data are consistent with a hypothesis suggesting that NO could attenuate VE-cadherin-mediated vascular integrity in human chronic inflammation.	19037921
Inflammation, Crohn Disease	Altered Intercellular Communication	DcR3 may promote inflammation in Crohn's disease by inhibiting CD95L-induced apoptosis of epithelial and immune cells as well as by inducing NF-kappaB activation.	19039087
Intraocular inflammation	Altered Intercellular Communication	We report two cases of true capsular exfoliation occurring in elderly patients with no known history of prolonged heat exposure or intraocular inflammation.	19039471
Polymyositis, Inflammation	Altered Intercellular Communication	Polymyositis is an inflammation of muscle tissue of unknown etiology.	19040148
Cataract, Eye pain, Inflammation	Altered Intercellular Communication	Nepafenac dosing frequency for ocular pain and inflammation associated with cataract surgery.	19040348
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	Nepafenac ophthalmic suspension 0.1% was well tolerated and effectively resolved ocular inflammation and increased the incidence of ocular pain-free patients following cataract surgery when dosed QD, BID, or TID.	19040348
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Impact of chronic kidney disease on postinfarction inflammation, oxidative stress, and left ventricular remodeling.	19041046
Infarction, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Patients with CKD had poorer clinical outcomes and accelerated infarct expansion in association with enhanced inflammation and oxidative stress, as compared with non-CKD patients, suggesting a major impact of CKD in the development of LV remodeling after MI.	19041046
Airway structure, Lung, Acute Lung Injury, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	Many surviving victims developed significant pulmonary signs and severe airway inflammation; 41 (58%) hospitalized persons met PO2/FiO2 criteria for acute respiratory distress syndrome or acute lung injury.	19041527
vascular inflammations, Hypertension, CTCAE, Diabetes Mellitus, diabetic	Altered Intercellular Communication	We conclude that candesartan may improve vascular inflammation independent of its effect on hypertension in diabetes, thus suggesting its efficacy in diabetic patients.	19043252
ACSM3 gene, Inflammation	Altered Intercellular Communication	Serum IL-6 values were clearly lower, suggesting CNS inflammation in SAH.	19043359
Inflammation, Hyperparathyroidism, Primary, Thrombophilia	Altered Intercellular Communication	Biomarkers of hypercoagulability and inflammation in primary hyperparathyroidism.	19043371
Inflammation, Hyperparathyroidism, Primary, Thrombophilia, Cardiovascular Diseases	Altered Intercellular Communication	The study was conducted to determine biomarkers of hypercoagulability and inflammation for cardiovascular disease in patients with primary hyperparathyroidism.	19043371
Inflammation	Altered Intercellular Communication	Forty seven mutations were detected by sequencing of p16 exon 2 in 44 BE patients (14.5%) with a mutation spectrum consistent with that caused by oxidative damage and chronic inflammation.	19043591
Airway structure, Inflammation, Bronchial Hyperreactivity	Altered Intercellular Communication	Chronic inflammation in asthmatic airways leads to bronchial hyper-responsiveness (BHR) and the development of structural changes.	19043669
Inflammation, Asthma	Altered Intercellular Communication	BHR was not correlated with features of mucosal inflammation and was lower in steroid-treated patients with long-standing asthma than in subjects with newly diagnosed asthma untreated with steroids.	19043669
Inflammation	Altered Intercellular Communication	(R)-[(11)C]PK11195 binds to peripheral benzodiazepine receptors, expressed on macrophages, and may be used to quantify inflammation using positron emission tomography (PET).	19043704
Inflammation, Degenerative disorder, Neoplasms	Altered Intercellular Communication	Imbalances between these enzymes and inhibitors may cause pathological processes such as chronic inflammation, degenerative disease and tumour invasion.	19043814
Inflammation, Granuloma	Altered Intercellular Communication	Histological analysis revealed chronic inflammation and granuloma with giant cells surrounding Fasciola hepatica eggs.	19046753
Inflammation	Altered Intercellular Communication	Erratic localization of F. hepatica reveals a pathology involving chronic inflammation caused by a sexually mature parasite, although according to theory only immature parasites are located in ectopic lesions.	19046753
Hydrocephalus	Altered Intercellular Communication	CSF neurotransmitter metabolites and neuropsychiatric symptomatology in patients with normal pressure hydrocephalus.	19046799
Hydrocephalus	Altered Intercellular Communication	Patients with normal pressure hydrocephalus (NPH) may exhibit certain neuropsychiatric symptomatology, possibly related to alterations in central neurotransmitter activity.	19046799
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Inflammation has emerged as a mediator of prostate cancer metastatic progression.	19047106
Inflammation, Thrombosis	Altered Intercellular Communication	These findings underscore the clinical importance of the interaction between thrombosis and inflammation in the pathogenesis of AMI.	19047776
Osteogenesis, Fibrous, Chronic inflammation	Altered Intercellular Communication	It consisted of the following 4 elements: fibrous tissue with chronic inflammation, young cartilage with chondroblastlike cells, young ossification with focal osteoblastlike and osteoclastlike cells, and collagenous tissue.	19047901
Communicable Diseases, Inflammation	Altered Intercellular Communication	Disease persisted for longer than infection (median 21 (15-32) weeks) versus 17 (12-24) weeks), with an estimated median duration of post-infection inflammation of 5 (3-8) weeks.	19048024
Perivascular Lymphocytic Infiltrate, Hemorrhage, Inflammation	Altered Intercellular Communication	The microscopic examination showed a generalized perivascular lymphocytic and neutrophilic inflammation in small and medium vessels with intense diapedesis bleeding.	19048537
Systemic Inflammatory Response Syndrome, Infection	Altered Intercellular Communication	Systemic inflammatory response syndrome (SIRS) can be related to acute inflammatory conditions that can be sometimes missed and inappropriately managed as severe infections.	19048706
Inflammation, Behcet Syndrome	Altered Intercellular Communication	In 79.5% of cases, inflammatory infiltrates were moderate to severe in degree; the most widespread inflammation was seen in Takayasu aortitis, systemic erythematosus lupus-associated aortitis, and in Behcet's disease.	19049742
Inflammation, human papillomavirus, Ulcer, Herpes Simplex Infections, Candida (fungus)	Altered Intercellular Communication	The histopathologic findings in the esophageal ulcers (22 biopsies) were non-specific inflammation (31.8%), HSV (36.4%), Candida (13.6%), CMV (13.6%), or HPV disease (4.5%).	19051024
Inflammation, Traumatic injury	Altered Intercellular Communication	This syndrome can occur after parotidectomy or after trauma, injury or inflammation of the parotid, the submandibular glands, or of cervical and thoracic parts of the sympathetic trunk.	19051482
Inflammation, Fibrinolysis	Altered Intercellular Communication	hsCRP, sICAM-1 and TAFI in hemodialysis patients: linking inflammation and hypofibrinolysis to cardiovascular events.	19052466
Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Fibrinolysis, Chronic Kidney Diseases	Altered Intercellular Communication	Growing evidence suggests that inflammation, oxidative stress and hypofibrinolysis may have a pivotal role in the high prevalence of cardiovascular disease (CVD) in chronic kidney disease (CKD) patients.	19052466
Inflammation, Fibrinolysis	Altered Intercellular Communication	This study demonstrates the association of inflammation and hypofibrinolysis with hemodialysis especially in patients with CVD.	19052466
Inflammation, Arthritis, bone destruction	Altered Intercellular Communication	In chronic arthritis cartilage and bone destruction occur as a consequence of synovial inflammation.	19052752
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	We show that human cells induced to senesce by genotoxic stress secrete myriad factors associated with inflammation and malignancy.	19053174
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Compared with echocardiography, MRI appears to provide additional information by visualising myocardial fibrosis and inflammation.	19054830
Peptic Ulcer	Altered Intercellular Communication	A non-significant association was found between CCND1 G870A genotypes and the risk of peptic ulcer diseases as well as histological severity of acute or chronic inflammation.	19055446
Cessation of life, Inflammation, cell injury	Altered Intercellular Communication	This may represent an auto-protective mechanism where the neutrophils in the already inflamed host may, by this mechanism, avoid excessive inflammation reducing the risk of further host cell injury and death.	19056020
Inflammation, Cardiovascular morbidity	Altered Intercellular Communication	Increased levels of interleukin 6 (IL-6), a marker for systemic inflammation, have been associated with cardiovascular morbidity and mortality.	19056105
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Malnutrition	Altered Intercellular Communication	Malnutrition and continuous systemic inflammation occur frequently in patients with chronic obstructive pulmonary disease (COPD).	19056239
ARCN1 gene, Inflammation	Altered Intercellular Communication	Its plasma level and relation with nutritional status and inflammation in COPD remain unknown.	19056239
Inflammation, Spinal Cord Injuries	Altered Intercellular Communication	Although the importance of intraspinal inflammation after human spinal cord injury is appreciated, the role of the systemic inflammatory response to this injury is not widely recognised.	19056384
Chronic inflammation	Altered Intercellular Communication	Light microscopy demonstrated fibrous lesions admixed with chronic inflammation.	19057967
Inflammation, Thrombocytosis	Altered Intercellular Communication	The degree of thrombocytosis was related to the degree of inflammation measured by the ESR.	19058606
Aneurysm, Inflammation, Edema	Altered Intercellular Communication	In addition to the pulsatile flow and/or compression from the expanded aneurysm, local inflammation in the aneurysm wall may play an important role in such edema formation.	19058909
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	To specifically compare the effect of two hydroxyethyl starches (HES) on the splanchnic microcirculation and systemic inflammation during abdominal aortic aneurysm (AAA) surgery.	19058981
S-linalool synthase activity, Inflammation, physiopathological	Altered Intercellular Communication	C-reactive protein (CRP) and lung-injury score (LIS) were used as markers of systemic inflammation and end-organ dysfunction respectively.	19058981
Inflammation	Altered Intercellular Communication	During AAA surgery, HES200/0.62 provides the best splanchnic microcirculation protection, also reducing inflammation and duration of ventilation.	19058981
Inflammation	Altered Intercellular Communication	Inflammation and joint loads are pathways commonly believed to cause or to exacerbate the disease process.	19059026
Inflammation, Rectal Necrotic Lesion	Altered Intercellular Communication	Delayed radionecrosis of rectum presenting as soft tissue inflammation of thigh--an unusual case.	19059152
Inflammation, Rectal Necrotic Lesion	Altered Intercellular Communication	This is a case report of a 53-yr-old gentleman with soft tissue inflammation of the thigh, secondary to delayed radionecrosis of rectum.	19059152
Inflammation, Hypertension, CTCAE, Atherosclerosis	Altered Intercellular Communication	Markers of inflammation are strong predictors of subclinical and clinical atherosclerosis in women with hypertension.	19060627
Inflammation, Squamous cell carcinoma	Altered Intercellular Communication	Clinical monitoring for development of squamous-cell carcinoma in areas of chronic inflammation and sun-exposure is imperative.	19061609
Inflammation, Corneal Opacity	Altered Intercellular Communication	There was simultaneously an acceleration of transition of inflammation to a phase of reparation with the formation of corneal opacity of less intensity and dimension.	19062556
Inflammation, Cardiovascular Diseases, Diabetes Mellitus	Altered Intercellular Communication	These results show that low birth weight is associated with increased systemic inflammation as depicted by the WBC count in childhood and adulthood, thereby potentially linking fetal growth retardation to cardiovascular disease and diabetes.	19064646
Transfusion-Related Acute Lung Injury	Altered Intercellular Communication	Loss of red cell chemokine scavenging promotes transfusion-related lung inflammation.	19064726
Pneumonitis	Altered Intercellular Communication	Thus, reduction in erythrocyte chemokine scavenging is one functional consequence of the storage lesion by which RBC transfusion can augment existing lung inflammation.	19064726
Refractory anemias, Inflammation, Amyloidosis	Altered Intercellular Communication	In RA patients with amyloid at re-examination, amyloidosis had been diagnosed before autopsy in 37%, and these patients had more inflammation and longer disease duration than RA patients without amyloid.	19065298
Refractory anemias, Inflammation, Amyloidosis	Altered Intercellular Communication	In patients with active and long-lasting RA, a systematic search for amyloid may enable early diagnosis of amyloidosis, which will require effective suppression of inflammation.	19065298
Communicable Diseases, Inflammation	Altered Intercellular Communication	Besides a general infection constellation, histologic examination of affected skin and mucosa revealed ulceration with chronic-granulomatous inflammation with Langerhans giant cells.	19065498
Inflammation, ovarian neoplasm	Altered Intercellular Communication	Markers of inflammation and risk of ovarian cancer in Los Angeles County.	19065661
Inflammation, ovarian neoplasm	Altered Intercellular Communication	Factors that increase inflammation have been suggested to influence the development of ovarian cancer, but these factors have not been well studied.	19065661
Inflammation, ovarian neoplasm	Altered Intercellular Communication	The NSAID finding was unexpected and suggests that factors associated with inflammation are associated with ovarian cancer risk.	19065661
Dental Surface Disorder, Pterygium Of Conjunctiva And Cornea, Conjunctivitis	Altered Intercellular Communication	Pterygium is a frequent ocular surface disorder of unknown origin characterized by chronic conjunctival inflammation with a clear central cornea in most patients.	19065986
Intraocular inflammation	Altered Intercellular Communication	Remissions of intraocular inflammation of at least 1 year were noted in 10/29 (34%) of patients.	19066184
Intraocular inflammation	Altered Intercellular Communication	One-third of IU patients achieved a remission of their intraocular inflammation for longer than 1 year and had a mean time-to-remission of 8.6 years.	19066184
Inflammation, Microcytosis, Cerebrovascular accident, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	The authors evaluated anemia prevalence (using World Health Organization criteria) among 19,836 blacks and whites recruited in 2003-2007 for the REasons for Geographic And Racial Differences in Stroke Renal Ancillary study and characterized anemia by 3 anemia-associated conditions (chronic kidney disease, inflammation, and microcytosis).	19066309
Microcytosis, Inflammation, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	Among those with anemia, chronic kidney disease was less common among blacks than whites (22% vs. 34%), whereas inflammation (18% vs. 14%) and microcytosis (22% vs. 11%) were more common.	19066309
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Further, inflammation in CD but not UC patients induced massive upregulation of beta1i and beta2i in the colon and terminal ileum, indicating the importance of this protein complex as a disease marker.	19067411
Neoplasms, Malignant Neoplasms	Altered Intercellular Communication	MNGCs were seen in some reactive or inflammatory conditions, benign neoplasms and malignant neoplasms.	19068670
Inflammatory Bowel Diseases, Functional disorder	Altered Intercellular Communication	Fecal calprotectin test is a simple, non-invasive, rapid and inexpensive diagnostic tool allowing differentiation between GIT functional disorders and inflammatory conditions and relapse prediction in non-specific inflammatory bowel disease.	19069028
Inflammation, Retinal Hemorrhage, Edema	Altered Intercellular Communication	In his left eye, only mild inflammation occurred in the anterior chamber, but extensive inflammation such as sheathing of retinal vessels, retinal hemorrhage, and edema of the optic disc was present.	19069383
Vasculitis, Inflammation	Altered Intercellular Communication	Moreover, extensive inflammation was now present in both the anterior and posterior segments, and the sheathing of the retinal vessels developed to frosted branch-like angiitis.	19069383
Inflammation, metabolic disturbance, Acidosis, Lactic	Altered Intercellular Communication	Lactic acidosis is an integral index of metabolic disturbances and severity of inflammation processes.	19069459
Inflammation, Acute Disease, Disease, Serositis	Altered Intercellular Communication	PCTS may proceed both as an acute disease and as a mild disorder characterized by general inflammation and obscure serositis making difficult its diagnosis.	19069464
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Neither chronic inflammation nor malignancy was revealed and, hence, no causal treatment could have been established.	19069686
Inflammation, Acanthosis	Altered Intercellular Communication	The lesions showed hyperparakeratosis with a characteristic frayed, shaggy, peeling surface, and acanthosis with insignificant inflammation.	19070760
Inflammation, Discitis, Back Pain, Fever, CTCAE	Altered Intercellular Communication	Spontaneous spondylodiscitis should be considered in every patient with back pain accompanied by fever and laboratory markers of inflammation.	19071050
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Forty of these patients (82%) had a decrease in fibrosis score, and 45 (92%) had a decrease in combined inflammation score.	19072828
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In a blind rescoring of 49 paired pretreatment and long-term follow-up biopsies, 82% improved fibrosis scores and 92% improved at least one component of inflammation.	19072828
Dehydration, Inflammation, Pain Distress Question	Altered Intercellular Communication	Wounds were evaluated for 60 up to days regarding wound healing, water loss, inflammation, and pain alleviation.	19073386
Fever, CTCAE, Communicable Diseases, Diarrhea, How Often Experienced Abdominal Discomfort, Acute and chronic inflammation, Weight decreased	Altered Intercellular Communication	The second patient developed severe symptomatic chronic infection with diffuse abdominal discomfort, fever, transient transplant dysfunction, recurrent episodes of diarrhoea, weight loss and histological signs of chronic intestinal inflammation.	19073655
Minimal Disseminated Disease, Depressive disorder, Inflammation, Bipolar Disorder	Altered Intercellular Communication	To examine the extent to which a common genetic pathway is also involved in the relationship between depressive symptoms, in the absence of major depressive disorder (MDD), and inflammation.	19073752
Minimal Disseminated Disease, Inflammation	Altered Intercellular Communication	Recent data suggested that MDD and inflammation share common genes.	19073752
Inflammation, Bipolar Disorder	Altered Intercellular Communication	This covariation is due, in large part, to genes that are common to depressive symptoms and inflammation.	19073752
Pituitary Gland, Pituitary Adenoma	Altered Intercellular Communication	Patients with pituitary adenomas show a distinct pattern of increased anxiety-related personality traits compared with the general population, potentially as a result of the pituitary lesion and/or associated hormonal dysregulations and comorbidities.	19073833
Inflammation, Metabolic Syndrome X, Diabetes Mellitus	Altered Intercellular Communication	Although red meat consumption has been related to the prevalence of diabetes, few data are available showing the relation among red meat intake, inflammation, and metabolic syndrome.	19074209
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	In conclusion, increased red meat consumption is cross-sectionally associated with greater risk of metabolic syndrome and inflammation.	19074209
vascular inflammations, Endothelial dysfunction	Altered Intercellular Communication	Increased ROCK activity has been implicated in endothelial dysfunction and vascular inflammation.	19075102
Keratopathy, Keratitis, Corneal edema, Intraocular inflammation	Altered Intercellular Communication	In the 10 cases of Calotropis procera -induced keratitis reported here, the clinical picture showed corneal edema with striate keratopathy without any evidence of intraocular inflammation.	19075415
Airway structure, ARCN1 gene, asthma chronic	Altered Intercellular Communication	The pattern of airway inflammation in induced sputum of patients with chronic asthma is different from that of COPD patients with a similar FEV(1).	19075557
ARCN1 gene, Pulmonary Emphysema, Bronchitis, Airway structure	Altered Intercellular Communication	Among COPD patients, however, the pattern of airway inflammation shows no difference between chronic bronchitis and patients with pulmonary emphysema, suggesting that these two clinically and functionally distinct phenotypes share a common inflammatory pattern as detected by induced sputum.	19075557
Inflammation, Hypertension, CTCAE, Erectile dysfunction	Altered Intercellular Communication	Managing erectile dysfunction in hypertension: the effects of a continuous training programme on biomarker of inflammation.	19076137
Inflammation, SUNCT Syndrome	Altered Intercellular Communication	We suggest that ipsilateral paranasal sinusitis accompanied by the spreading of inflammation through a dehiscence in the lamina papyracea could lead to the development of SUNCT syndrome.	19076651
Benign prostatic hypertrophy	Altered Intercellular Communication	Histologic influence of doxazosin and finasteride in benign prostatic hyperplasia accompanying chronic inflammation.	19077407
Inflammation	Altered Intercellular Communication	We hypothesized that common confounders, such as protein-energy wasting (PEW) and inflammation could modulate this relationship.	19077418
Inflammation	Altered Intercellular Communication	In multivariate analysis, an NT-proBNP level above the cutoff of the receiver-operating curve (9,761 pg/ml) was associated with PEW (odds ratio = 2.30, p = 0.008) even following adjustment for age, dialysis vintage, inflammation and the Davies score.	19077418
Hepatic inflammation, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	Aminotransferase level is presumed to be a marker of hepatic inflammation, but uncertainty remains whether elevated aminotransferase levels are associated with an increased risk of hepatocellular carcinoma (HCC).	19077561
Malignant tumor of colon, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP) is a nonspecific marker of inflammation linked to cardiovascular disease and possibly colon cancer.	19077918
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	The normal intestinal flora is required for the development of intestinal inflammation in animal models of inflammatory bowel disease (IBD).	19079222
Burning sensation, Inflammation, Epigastric pain	Altered Intercellular Communication	The scores of epigastric pain, epigastric burning sensation and early satiety in patients with PI-FD were significantly higher than those in patients with NS-FD (P < 0.05 for all), so did the scores of histological chronic inflammation in gastric mucosa (P < 0.05).	19080199
Squamous cell carcinoma of esophagus	Altered Intercellular Communication	Inflammation-based prognostic score, prior to neoadjuvant chemoradiotherapy, predicts postoperative outcome in patients with esophageal squamous cell carcinoma.	19081014
Gastrointestinal inflammation	Altered Intercellular Communication	There was no correlation between localisation or extent of the intestinal inflammation and presence of AS and SpA.	19082597
Inflammation, Atherosclerosis, Coronary heart disease, Choline Dehydrogenase, Mitochondrial, atherosclerotic	Altered Intercellular Communication	P-selectin plays a key role in inflammation and atherosclerosis, and polymorphic variants of P-selectin were implicated in the pathogenesis of atherosclerotic and inflammatory changes, including coronary heart disease (CHD) in many ethnic groups.	19082691
Fibrosis Assessment, Chronic inflammation	Altered Intercellular Communication	Pathology from oral and facial lesions was consistent with granulation tissue and fibrosis with chronic inflammation.	19082722
Enterocolitis, Hirschsprung Disease, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Low incidence of enterocolitis and colonic mucosal inflammation in Norwegian patients with Hirschsprung's disease.	19082831
HD Term Type, Inflammation, Hirschsprung Disease	Altered Intercellular Communication	Hirschsprung's disease (HD) may be associated with inflammation in the colon.	19082831
HD Term Type, Inflammation	Altered Intercellular Communication	To learn more about these features, we examined our cohort of HD patients during a period of 6 years for inflammation in their colonic mucosa as well as for signs of HEC.	19082831
Inflammation, immunoglobulin A	Altered Intercellular Communication	Signs of inflammation were recorded in hematoxylin/eosin/saffron (HES)-stained sections and with fluorescence conjugated polyclonal antibodies to IgA and IgG applied on serial sections.	19082831
Inflammation	Altered Intercellular Communication	We identified inflammation in resected colonic segments from 17 out of 36 patients.	19082831
Inflammation	Altered Intercellular Communication	Thirteen of these 17 had a diverting colostomy, and only one out of 14 patients with colostomy had no inflammation.	19082831
Inflammation	Altered Intercellular Communication	By immunofluorescence (IF) staining, inflammation was found in resected colonic segments from five patients.	19082831
Inflammation, Ganglia	Altered Intercellular Communication	Inflammation in the resected specimen was mainly found in patients with a diverting colostomy, and then in both ganglionic and aganglionic colon.	19082831
Lupus Erythematosus, Systemic, Skin lesion, Leukopenia, Nephrotic Syndrome, Anemia, Arthritis, Thrombocytopenia	Altered Intercellular Communication	A 31-year-old Chinese lady presented with severe SLE with nephrotic syndrome, anemia, leucopenia and thrombocytopenia, skin lesions, and joint inflammation after failing previous standard therapy.	19083076
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	We concluded that decreased levels of serum magnesium are associated with increased risk for metabolic syndrome, perhaps by a low-grade inflammation process.	19083473
Inflammation, Chronic disease	Altered Intercellular Communication	Biomedical research has led to the hypothesis that inflammation is the culprit behind almost every modern chronic illness.	19083655
Inflammation	Altered Intercellular Communication	Hence there is interest in techniques that can resolve acute and chronic inflammation.	19083655
Pain Distress Question, Inflammation	Altered Intercellular Communication	When done during sleep, earthing normalizes the daily cortisol rhythm, improves sleep and reduces pain and inflammation.	19083655
Inflammation	Altered Intercellular Communication	Subsequent surgical evaluation and positron emission tomography imaging showed evidence of active inflammation of the proximal aorta and coronary arteries.	19083962
Inflammation, Homocysteinemia	Altered Intercellular Communication	Taken together, the clinical data and in vitro experiments support the hypothesis that moderate homocysteinemia and low-grade inflammation synergically enhance NADPH oxidase activity in the elderly.	19084060
Inflammation	Altered Intercellular Communication	However, chronic inflammation can affect other organs including the liver.	19084266
Acute and chronic inflammation	Altered Intercellular Communication	The biopsies typically showed mild portal and mild-to-moderate lobular chronic inflammation with minimal or absent interface activity.	19084266
Inflammation, Hepatitis	Altered Intercellular Communication	Overall, the inflammatory changes in the biopsies were reminiscent of those seen in individuals with chronic inflammation of the gut, which can lead to translocation of intestinal luminal antigens to the liver and a mild hepatitis.	19084266
Gastrointestinal inflammation	Altered Intercellular Communication	Subsequent review of concurrent intestinal biopsies available in 7 individuals showed intestinal inflammation in 5 of 7 cases.	19084266
Fibrosis Assessment	Altered Intercellular Communication	In conclusion, liver biopsies in individuals with common variable immunodeficiency show mild portal and lobular inflammation with no or mild portal fibrosis.	19084266
Immunologic Deficiency Syndromes	Altered Intercellular Communication	The etiology of the common variable immunodeficiency hepatitis remains unclear but, in some cases, may be secondary to mucosal inflammation in the gastrointestinal tract.	19084266
atherosclerotic	Altered Intercellular Communication	Atherosclerotic inflammation triggers osteogenic bone transformation in calcified and stenotic human aortic valves: still a matter of debate.	19084515
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Systemic inflammation is associated with both the dietary intake of magnesium, and depression.	19085527
ARCN1 gene, Inflammation	Altered Intercellular Communication	Fifteen genes, particular to inflammation, immune response, and cell-to-cell signaling, were differentially expressed in COPD subjects, versus 4 genes in healthy subjects.	19085563
ARCN1 gene, Inflammation	Altered Intercellular Communication	Fifteen genes, particular to inflammation, immune response, and cell-to-cell signaling, were differentially expressed in COPD subjects, versus 4 genes in healthy subjects.	19085563
Inflammation, Intracranial Hypertension, Papilledema	Altered Intercellular Communication	The most common ophthalmological pathology in POEMS syndrome is papilledema, the etiology of which could be infiltrative, intracranial hypertension, inflammation or an increase of the vascular permeability.	19085642
Weight Gain, Inflammation, Sarcopenia	Altered Intercellular Communication	The increase of skeletal muscle AGEs/RAGE and markers of inflammation and oxidative injury in association with weight gain and old age suggest a pathogenic role of AGEs in weight gain and in sarcopenia of aging.	19086911
Glioma, Inflammation	Altered Intercellular Communication	The incidence, correlation with tumor-infiltrating inflammation, and prognosis of phosphorylated STAT3 expression in human gliomas.	19088040
Inflammation	Altered Intercellular Communication	When the gastric epithelium and associated inflammation were examined for expression of MLH1 and MGMT, an overall increase in expression was observed.	19089477
Inflammation, Hemorrhage, Hyperplasia, Granulation finding, Atrophic	Altered Intercellular Communication	Clinicopathologic characteristics showed mucosal inflammation accompanied by erosion, granulation tissue hyperplasia and gland atrophy, lamina propria hemorrhage, and macrophages with hemosiderin pigmentation in submucosa in particular.	19089615
Inflammation, Helicobacter Pylori-Related Carcinoma	Altered Intercellular Communication	Superoxide has been implicated in the pathogenesis of Helicobacter pylori-related diseases through inflammation.	19089790
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Positron emission tomography (PET) used to image subclinical inflammation associated with ulcerative colitis (UC) in remission.	19090558
Refractory anemias, Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The components of the metabolic syndrome may already be extensively modified by other processes in RA (including chronic inflammation and treatments other than GCs), leaving little scope for additive effects of GCs.	19091101
Granulomatous inflammation	Altered Intercellular Communication	We present a case of LH-ALCL involving skin mimicking granulomatous inflammation.	19091487
Inflammation, Community-Acquired Infections	Altered Intercellular Communication	The cohort of patients included adults with systemic inflammation and suspicion of community-acquired bacterial infection.	19091808
Inflammation	Altered Intercellular Communication	Inflammatory cells were seen, but there was no evidence of chronic inflammation.	19092016
Inflammation, Metabolic Syndrome X, Hyperglycemia	Altered Intercellular Communication	Interleukin-18 is a strong predictor of cardiovascular events in elderly men with the metabolic syndrome: synergistic effect of inflammation and hyperglycemia.	19092166
Hypokalemia, Hyperinsulinism, Thyrotoxicosis, Paralysed	Altered Intercellular Communication	Beside thyrotoxicosis, a number of other hormonal factors have been hypothesized to contribute to hypokalaemic thyrotoxic periodic paralysis, particularly postprandial hyperinsulinaemia and testosterone.	19092328
Nausea, Inflammation	Altered Intercellular Communication	Because steroids effectively reduce nausea and inflammation, a preoperative administration of steroids could improve these thyroidectomy outcomes.	19092351
Corneal decompensation, Inflammation	Altered Intercellular Communication	There was no anterior chamber inflammation and no evidence of corneal decompensation.	19092467
Inflammation	Altered Intercellular Communication	We speculate that either the cutaneous surgery during cochlear implantation or the skin inflammation that commonly occurs near the magnet might have triggered the disorder.	19094119
Sepsis, Primary malignant neoplasm, Scurvy, Acute inflammation	Altered Intercellular Communication	However, an acute form of scurvy can occur in patients with an acute systemic inflammatory response, which is produced by sepsis, medications, cancer or acute inflammation.	19094121
Inflammation, Pseudolymphoma, Carcinoma, Lymphoma	Altered Intercellular Communication	There were altogether 226 cases of reactive lymphoid hyperplasia, 202 cases of specific inflammation, 45 cases of malignant lymphoma and 107 cases of metastatic carcinoma.	19094489
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Resistin is a secreted factor that is elevated in rheumatoid arthritis (RA) and believed to drive joint inflammation in vivo.	19095472
Inflammation, Abscess, Actinomycosis	Altered Intercellular Communication	Other cystic inflammations can be the result of tuberculous abscesses, suppurated lymph nodes and actinomycosis.	19095694
Inflammation, Crohn Disease	Altered Intercellular Communication	In conclusion, nonmigrating dendritic cells that accumulate in the subepithelial dome and internalize nonpathogenic bacteria may be important for the onset and perpetuation of mucosal inflammation in Crohn's disease.	19095953
Inflammation, Ischemic stroke, Vascular Diseases	Altered Intercellular Communication	Inflammation plays a critical role in the development of vascular disease, and increased levels of the inflammatory biomarkers, lipoprotein-associated phospholipase A(2) (Lp-PLA(2)), and high-sensitivity C-reactive protein (hs-CRP) have been shown to be associated with an increased risk for ischemic stroke.	19095974
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by substantial chronic inflammation in the pulmonary compartment as well as in the systemic circulation.	19096002
Intraocular inflammation	Altered Intercellular Communication	Seventeen days after the operation, his corrected visual acuity was 1.0, the intraocular lens was well-seated, and there was no intraocular inflammation.	19096248
Refractory anemias, Inflammation, Rheumatoid Arthritis, Obesity	Altered Intercellular Communication	Obesity is characterised by low-grade inflammation and could potentially affect disease activity and severity in patients with rheumatoid arthritis (RA).	19096748
Sciatica	Altered Intercellular Communication	Value of perineural edema/inflammation detected by fat saturation sequences in lumbar magnetic resonance imaging of patients with unilateral sciatica.	19096956
Pain Distress Question	Altered Intercellular Communication	Perineural edema/inflammation corresponding to the pain location indicated by the pain drawings was sought on short-tau inversion recovery or fat-saturated T2-weighted images.	19096956
Inflammation, Hyperpigmentation	Altered Intercellular Communication	Given that p53 can be activated by various kinds of diverse stresses, including sun exposure, inflammation, and aging, this finding led us to examine the involvement of p53 in cytokine receptor signaling, which might result in skin hyperpigmentation.	19098008
Communicable Diseases, Inflammation	Altered Intercellular Communication	When handled or stepped on by humans, the spines can puncture the skin, causing an immediate painful reaction, followed by inflammation and possible infection.	19099322
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is characterized by synovial inflammation with local accumulation of mononuclear cells such as macrophages and lymphocytes.	19099567
Inflammation, Prostate carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Inflammation has been implicated as an etiological factor in several human cancers, including prostate cancer.	19099590
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Endothelial dysfunction may link these 2 processes and inflammation is closely related to endothelial dysfunction.	19100415
Inflammation, Corneal Endothelial Cell Loss	Altered Intercellular Communication	This cross-sectional study on serum concentrations of markers of endothelial damage and inflammation in relation to adhesion molecules was performed in 90 kidney allograft recipients and 30 healthy volunteers.	19100415
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Markers of endothelial dysfunction and inflammation were significantly elevated in kidney allograft recipients compared with control subjects.	19100415
Inflammation, Endothelium	Altered Intercellular Communication	As demonstrated in multiple regression analysis, kidney function was strictly linked to the degree of inflammation and endothelial injury.	19100415
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Chronic periglandular inflammation on prostate needle biopsy does not increase the likelihood of cancer on subsequent biopsy.	19100603
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Recent literature suggests a role for chronic inflammation in the development of prostate cancer.	19100603
Inflammation, Prostate carcinoma	Altered Intercellular Communication	We investigated the association of chronic periglandular inflammation on prostate needle biopsy with subsequent prostate cancer development and clinical disease features at presentation.	19100603
Inflammation	Altered Intercellular Communication	Chronic inflammation was defined as an inflammatory cell infiltrate composed predominately of lymphocytes in a periglandular distribution.	19100603
Prostate carcinoma, prostatitis	Altered Intercellular Communication	A subset of patients (n = 308) with follow-up biopsy results were used to identify if prostate inflammation predicted development of prostate cancer.	19100603
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Kaplan-Meier analysis demonstrated inflammation does not predict subsequent prostate cancer (P = .2).	19100603
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Although inflammation on initial and subsequent biopsy does not predict prostate cancer in this cohort, we cannot dismiss its role in prostate cancer pathogenesis.	19100603
Prostate carcinoma, prostatitis	Altered Intercellular Communication	Additional research is necessary to explore the relationship between prostate inflammation and prostate cancer development.	19100603
Seroma, Fibrosis Assessment, Neoplasms, Myositis	Altered Intercellular Communication	DCE-MRI differentiated rapidly enhancing soft tissue recurrences (11 patients) and residual tumours (6 patients) from slowly enhancing muscle inflammation, and non-enhancing fibrosis and seromas that usually did not enhance.	19101106
Edema, Myositis	Altered Intercellular Communication	Subcutaneous and cutaneous oedema and muscle inflammation was at least four times more frequent after adjunct radiotherapy than after resection alone.	19101106
Seroma, Inflammation, Fracture	Altered Intercellular Communication	Postoperative radiotherapy was associated with a significant number of patients with seromas, muscle, cutaneous and subcutaneous inflammation, and fractures.	19101106
vascular inflammations, Muscle Cells	Altered Intercellular Communication	Patients were assessed on admission for clinical characteristics, electrocardiographic findings, renal function, cardiac troponin T (cTnT), markers of myocyte injury (heart fatty acid-binding protein [H-FABP] and glycogen phosphorylase BB), neurohormonal activation (N-terminal-pro-brain natriuretic peptide [NT-pro-BNP]), hemostatic activity (fibrinogen and D-dimer), and vascular inflammation (high-sensitivity C-reactive protein, myeloperoxidase, matrix metalloproteinase-9, pregnancy-associated plasma protein-A, and soluble CD40 ligand).	19101224
Pleurisy, Ascites, Hydrothorax	Altered Intercellular Communication	We present a series of 5 consecutive patients with refractory hepatic hydrothorax who underwent combined thorascopically guided mechanical and chemical pleurodesis aided by an intraperitoneal drain that prevented reaccumulation of the ascites while pleural inflammation and adhesion were progressing.	19101306
Pain Distress Question, Acute inflammation	Altered Intercellular Communication	Difluprednate ophthalmic emulsion 0.05% for postoperative inflammation and pain.	19101421
Inflammation, Adverse event, Pain Distress Question	Altered Intercellular Communication	Outcome measures included cleared anterior chamber inflammation (grade 0,	19101421
Pain Distress Question, Inflammatory abnormality of the eye	Altered Intercellular Communication	Both difluprednate dosage regimens reduced postoperative ocular inflammation and pain safely and effectively compared with the placebo.	19101421
Inflammation, Pain Distress Question	Altered Intercellular Communication	A greater proportion of difluprednate-treated patients had a reduction in inflammation and pain at 8 days and 15 days.	19101421
Inflammation, Pain Distress Question	Altered Intercellular Communication	Difluprednate given 2 or 4 times a day cleared postoperative inflammation and reduced pain rapidly and effectively.	19101421
Inflammation, Endophthalmitis, CTCAE	Altered Intercellular Communication	To evaluate laser flare photometry in measuring aqueous humor inflammation in chronic pseudophakic endophthalmitis.	19101431
Orbital Pseudotumor	Altered Intercellular Communication	During the course of treatment, the patient exhibited an acute increase in orbital inflammation, which required immediate surgical intervention with postsurgical intravenous antibiotic administration.	19101481
Inflammation, Heart Failure, Systolic	Altered Intercellular Communication	Exercise training in older patients with systolic heart failure: adherence, exercise capacity, inflammation and glycemic control.	19101855
Hepatic necrosis, Inflammation, Cholestasis	Altered Intercellular Communication	The liver biopsy was performed and the microscopic examination revealed cholestasis with bile plugs without any signs of inflammation and liver tissue necrosis.	19102078
Gastritis	Altered Intercellular Communication	NADPH oxidase, a major source of superoxide generation play a critical role in H. pylori related gastric inflammation.	19102345
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Cytokine-induced human IFN-gamma-secreting effector-memory Th cells in chronic autoimmune inflammation.	19104082
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Among these cells, we detected a substantial fraction that secretes IFN-gamma directly ex vivo but lacks 4-1BB expression, indicating that cytokine-induced IFN-gamma(+) Th cells operate in autoimmune inflammation.	19104082
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Previous case reports have mainly focused on an association with malignancy and bowel inflammation.	19104111
Inflammation, Condylomata Acuminata, Cervical Squamous Cell Carcinoma, Cervical intraepithelial neoplasia grade 2, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	Confirmed by pathological diagnosis of cervical biopsy, 112 cases were chronic inflammation (60.87%), 33 CIN I (17.93%), 17 CIN II (9.24%), 8 CIN III (4.35%), 4 cervical squamous carcinoma (2.17%) and 10 condyloma (5.43%).	19105350
Cervical Squamous Cell Carcinoma, Inflammation, Condylomata Acuminata, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	Of the 184 women with cytological ASCUS, 124 (67.39%) cases were positive in high-risk HPV test among which 66 cases were histologically confirmed as chronic inflammation (53.23%), 22 as CIN I (17.74%), 16 as CIN II (12.90%), 8 as CIN III (6.45%), 4 as cervical squamous carcinoma (3.23%) and 8 as condyloma (6.45%).	19105350
Panniculitis, Hepatitis B	Altered Intercellular Communication	The hepatitis B reactivation rate of patients with obvious hepatic tissue inflammation (> or = G2) was 27.0% (33/122) and the rate of the patients with mild hepatic tissue inflammation (G0-G1) was 2.0% (2/98), showing significant differences (x2=25.41, P less than 0.01).	19105928
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	There were no obvious differences about the inflammation grade between age less than 40 years old and > or = 40 years old group cases (x2=0.62, P more than 0.05), but there were significant statistical differences about the fibrosis stage (x2=7.37, P less than 0.01), showing fibrosis stage of more than 40 years old group cases was clearly higher than the less than 40 years old group cases.	19105928
Inflammation, Hepatitis B, Hepatitis	Altered Intercellular Communication	The hepatic tissue pathology for most chronic HBV carriers (55%) had significant abnormalities (inflammation grade > or = G2), and the rates of hepatitis B reactivation were highly relevant to the liver inflammation grades and the ages of the patients.	19105928
Refractory anemias, Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Part of the deleterious effects of systemic inflammation on the cardiovascular system of patients with RA may be exerted via increased propensity to hypertension.	19106168
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	This association remained significant after adjustment for other hypertension risk factors and medication (odds ratio = 1.96; 95% CI 1.02, 3.77; P = 0.044), and was more pronounced in patients with increased systemic inflammation.	19106168
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation changed along with the development of a specific antibody titer in the serum.	19106778
Dermatitis, Atopic, Acute viral bronchiolitis	Altered Intercellular Communication	[Atopic dermatitis aggravates the allergic airways inflammation in acute viral bronchiolitis].	19106904
Airway structure, Allergic asthma	Altered Intercellular Communication	Exhaled nitric oxide (FeNO) is a putative non-invasive marker of eosinophilic airway inflammation with a good predictive value for allergic asthma in preschool children.	19106904
Inflammatory abnormality of the eye	Altered Intercellular Communication	Tolerance was evaluated by the scarring at the 7th day and ocular inflammation.	19107072
Hashimoto Disease, Autoimmune Disorder, CTCAE	Altered Intercellular Communication	Hashimoto's thyroiditis is the most common inflammatory condition of the thyroid gland; and is a frequently-occurring autoimmune disorder manifesting predominantly in middle-aged women.	19108029
Allergic asthma, Virus Diseases, Airway structure	Altered Intercellular Communication	Atopic asthma pathogenesis is driven by the combined effects of airway inflammation generated during responses to viral infections and aeroallergens, and both these pathways are regulated by dendritic cells (DC) that differentiate locally from monocytic precursors.	19109137
Immunologic Deficiency Syndromes, Inflammation	Altered Intercellular Communication	the coexistence of inflammation and immunodeficiency, as well as c) a complex mechanism of remodelling elicited by inflammaging, explaining the long and winding pathophysiological road that goes from robustness to frailty.	19109735
Chronic disease	Altered Intercellular Communication	"Inflamm-aging" denotes the up-regulation of certain pro-inflammatory cytokines at older ages, and associated chronic diseases.	19109735
Immunologic Deficiency Syndromes, Inflammation	Altered Intercellular Communication	the coexistence of inflammation and immunodeficiency, as well as c) a complex mechanism of remodelling elicited by inflammaging, explaining the long and winding pathophysiological road that goes from robustness to frailty.	19109735
Inflammation	Altered Intercellular Communication	Cardiopulmonary bypass is associated with systemic inflammation that may contribute to increased perioperative mortality.	19109738
Inflammation, Multiple Trauma	Altered Intercellular Communication	Systemic inflammation subsequent to polytrauma is connected to neutrophil (PMN) dysregulation characterized by reduced NF-kB-translocation and cytokine expression.	19109749
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation, hemostasis, and the risk of kidney function decline in the Atherosclerosis Risk in Communities (ARIC) Study.	19110358
Inflammation	Altered Intercellular Communication	Inflammation and hemostasis may increase the risk of kidney function decline; however, data from prospective studies are sparse.	19110358
Inflammation	Altered Intercellular Communication	Markers of inflammation and hemostasis are associated with greater risk of kidney function decrease.	19110358
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Findings suggest that inflammation and hemostasis are antecedent pathways for CKD.	19110358
Inflammation, Tumor necrosis, Lupus Erythematosus, Systemic	Altered Intercellular Communication	To determine the effect of inflammation through exposure to tumour necrosis factor (TNF)alpha on T lymphocytes in patients with systemic lupus erythematosus (SLE).	19110660
Inflammation, Dental Plaque	Altered Intercellular Communication	Uptake was correlated to quantitative gene expression of known markers of inflammation and plaque vulnerability.	19112034
Inflammation, Pruritus	Altered Intercellular Communication	After 2 months, a marked improvement was observed in regards to the patient's pruritus and inflammation.	19112768
Inflammation, Dry Eye Syndromes	Altered Intercellular Communication	Inflammation may play role in pathogenesis of dry eye syndrome.	19112861
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP), a plasma inflammation marker, has been known to play a role in the development of cardiovascular diseases.	19114404
acute necrotizing, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	A transnasal biopsy showed an acute necrotising, non-specific and non-granulomatous inflammation.	19114541
Sepsis, Communicable Diseases, Inflammation	Altered Intercellular Communication	Severe sepsis induced a stronger AVP response than infection without systemic inflammation.	19114902
Sepsis, Inflammation, Multiple Organ Failure	Altered Intercellular Communication	Post hoc citrate appeared particularly beneficial after surgery, in sepsis and severe multiple organ failure, suggesting interference with inflammation.	19114912
Inflammation	Altered Intercellular Communication	Apolipoprotein (apo) E phenotype has been associated with inflammation markers.	19115037
Inflammatory abnormality of the eye	Altered Intercellular Communication	However, the role of sPLA2-IIa in chronic ocular surface inflammation has yet to be determined.	19116146
Inflammation, Ocular Surface Disease Index	Altered Intercellular Communication	In the current study, we examined the potential role of sPLA2-IIa in inflammation of ocular surface diseases.	19116146
Inflammatory abnormality of the eye	Altered Intercellular Communication	To our knowledge, this is the first report regarding the role of sPLA2-IIa as an inflammatory mediator in ocular surface inflammation.	19116146
Inflammatory abnormality of the eye	Altered Intercellular Communication	These findings indicate that sPLA2-IIa may play an important role in chronic ocular surface inflammation, especially when the ocular surface is compromised.	19116146
Inflammation, Left Ventricular Hypertrophy	Altered Intercellular Communication	Disease duration is independently related to increased LV mass, suggesting a pathophysiologic link between chronic inflammation and LV hypertrophy.	19116901
Inflammation, Renal function, Failure (biologic function)	Altered Intercellular Communication	Symptomatic improvement was defined as time to relief of symptoms; clinical improvement, time to normalization of inflammatory parameters with symptomatic improvement; radiological changes, percentage of decrease in retroperitoneal mass; recurrence, as the need to increase steroid dose or add immunosuppressors because of reactivation of inflammation; and treatment failure, as persistence of signs of active inflammation and/or decrease in retroperitoneal mass less than 50% and/or deterioration in kidney function at the last visit.	19117656
Abnormal oral mucosa morphology, Inflammation, Inflammatory disorder	Altered Intercellular Communication	Of the colorectal specimens, 87 (90%) showed no mucosal abnormality (apart from the spirochetes); the other 10 showed mucosal inflammation but 6 of them had a diagnosis of another inflammatory disease process accounting for the inflammatory changes.	19117973
Inflammation, Tuberculosis, Breast Carcinoma, Malignant Pleural Mesothelioma	Altered Intercellular Communication	The IT knife biopsy was superior to SFF in 8 of 20 patients (malignant pleural mesothelioma in three, nonspecific inflammation in two, metastatic breast cancer in one, and tuberculosis in one).	19118434
Abscess, Inflammation	Altered Intercellular Communication	Cold steel EES-DCR was performed after the lacrimal abscess formation, and external dacryocystorhinostomy (E-DCR) was performed 1 to 2 weeks after resolution of the acute inflammation.	19118702
Inflammation, Atherosclerosis	Altered Intercellular Communication	A further objective was to investigate whether traditional risk factors, inflammation, or adipokines could explain the hypothesized relationship between VAT and atherosclerosis.	19118830
Asthma, Pneumonia	Altered Intercellular Communication	In patients with near-fatal asthma, factors for a poor prognosis included older age [48.47+/-3.53 vs. 64.69+/-2.59 years, p<0.05], chronic severe asthma, high values for inflammation-related laboratory markers (ESR, 8.75+/-2.05 vs. 23.88+/-4.40 mm/h, p=0.004; CRP, 1.72+/-0.46 vs. 6.68+/-9.36 mg/dL, p<0.05), asthma exacerbated by pneumonia (28.1 vs. 52.8%, p<0.05), and relatively low nutritional status (albumin, 4.00+/-0.14 vs. 3.51+/-0.10 g/dL, p<0.05).	19119253
Inflammation, Brain Abscess	Altered Intercellular Communication	These findings may be evidence of active inflammation working to sequestrate the lesion and protect the surrounding normal brain parenchyma from additional damage, even in the final stage of the brain abscess.	19119458
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis is characterized by inflammation, which may interfere with vascular integrity and augment intralesional microhemorrhage.	19119488
Inflammation, Thrombosis, Angina, Unstable, Rupture, Electrocardiogram: myocardial infarction (finding), Dental Plaque	Altered Intercellular Communication	Inflammation plays a critical role in all stages of atherogenesis, including plaque destabilization leading to the rupture and local thrombosis, clinically manifested as unstable angina (UA) or myocardial infarction (MI).	19120546
Pain Distress Question, Inflammation	Altered Intercellular Communication	Kinins are peptides involved in vasodilation, vascular permeability, pain and inflammation.	19120546
Arterial Stiffness, Inflammation, Ischemic stroke	Altered Intercellular Communication	We studied the relationship of arterial stiffness, measured by carotid-femoral pulse wave velocity and inflammation, measured by serum erythrocyte sedimentation rate among 334 ischaemic stroke patients.	19120549
Arterial Stiffness, Inflammation, Ischemic stroke	Altered Intercellular Communication	Arterial stiffness and inflammation are associated among ischaemic stroke patients and are independent of established vascular risk factors.	19120549
methyldopa, Inflammation	Altered Intercellular Communication	We hypothesized that any compound effective against LIRD, which involves significant oxidative stress and inflammation, would be a candidate for further characterization for its potential application in AMD.	19121385
Inflammation	Altered Intercellular Communication	A main cause of PEW is inflammation, which may occur with or without clinically evident illness and can be associated with the most severe forms of PEW.	19121473
Hormone abnormality, Acidemia, Nephrotic Syndrome	Altered Intercellular Communication	Losses of nutrients during dialysis treatments or in urine (eg, the nephrotic syndrome), acidemia, and hormonal disorders can contribute to the development of PEW.	19121473
Inflammation, Heparin-induced thrombocytopenia, Thrombosis, Blood Vessel	Altered Intercellular Communication	In patients with intracranial inflammation, such as ours, the possibility of HIT has to be considered when heparin is used, since inflammatory cerebral lesions often cause vascular damage, which is an aggravating factor for HIT-associated thrombosis.	19122360
Inflammatory abnormality of the eye	Altered Intercellular Communication	It can be tapered and discontinued successfully without the return of ocular inflammation.	19123158
Inflammation	Altered Intercellular Communication	Histology revealed signs of chronic inflammation and neovascularization in the conjunctiva.	19123160
Inflammation	Altered Intercellular Communication	Histology suggests that late onset immunoreaction and chronic vasoconstriction cause chronic inflammation and neovascularization, respectively.	19123160
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Exhaled nitric oxide, systemic inflammation, and the spirometric response to inhaled fluticasone propionate in severe chronic obstructive pulmonary disease: a prospective study.	19124359
ARCN1 gene, Inflammation, Pneumonitis	Altered Intercellular Communication	In ex-smokers with severe COPD, a measure of local pulmonary inflammation, FENO, may be more closely associated with FEV1 responses to four weeks of ICS than are standard markers of systemic inflammation, serum CRP, IL-6, and IL-8.	19124359
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Accumulating evidence suggests a role for inflammation in the development and progression of cancer.	19124500
ovarian neoplasm, Pelvic Inflammatory Disease	Altered Intercellular Communication	Pelvic inflammation has been implicated in the genesis of ovarian cancer.	19125176
Diabetes Mellitus, Insulin-Dependent, Osteoporosis, Osteopenia	Altered Intercellular Communication	To determine the prevalence and biochemical/hormonal determinants of osteopenia and osteoporosis in adults with Type 1 diabetes.	19125760
Inflammation, Pharyngitis	Altered Intercellular Communication	Histological markers of inflammation and their correlation with pharyngitis.	19126133
Pharyngitis, Inflammation	Altered Intercellular Communication	However, the clinical diagnosis of pharyngitis does not correlate well with cellular inflammatory infiltrate and is therefore, not a reliable measure of underlying inflammation.	19126133
Inflammation, Weight decreased, NCI CTEP SDC Gastroesophageal Cancer Sub-Category Terminology	Altered Intercellular Communication	The influence of systemic inflammation, dietary intake and stage of disease on rate of weight loss in patients with gastro-oesophageal cancer.	19127266
Inflammation, Weight decreased, Gastrointestinal Stromal Sarcoma	Altered Intercellular Communication	Although weight loss is often a dominant symptom in patients with upper gastrointestinal malignancy, there is a lack of objective evidence describing changes in nutritional status and potential associations between weight loss, food intake, markers of systemic inflammation and stage of disease in such patients.	19127266
Inflammation, Weight decreased	Altered Intercellular Communication	Recognition that systemic inflammation plays a role in nutritional depletion may inform the development of appropriate therapeutic strategies to ameliorate weight loss, making patients more tolerant of cancer-modifying treatments such as chemotherapy.	19127266
Inflammation, Low Vision	Altered Intercellular Communication	Although the exact etiology and molecular pathogenesis of the atrophic ARMD are not fully understood, it is believed that oxidative stress and local inflammation play a major role in the pathologic processes and that the disease is triggered by dysfunction in the retinal pigment epithelia, leading to the degeneration of macular photoreceptor cells, followed by irreversible loss of vision.	19128888
Communicable Diseases, Malignant neoplasm of prostate, Inflammation	Altered Intercellular Communication	Furthermore, prostate cancers and premalignant precursors exhibit chronic inflammation, which suggests a possible infectious involvement.	19129009
Inflammation	Altered Intercellular Communication	It may become clinically evident when complicated by chronic inflammation or by growth.	19129053
Neurodegenerative Disorders, Inflammation, Cardiovascular Diseases, Chronic disease, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Subclinical inflammation confers an increased risk of type 2 diabetes, cardiovascular disease, neurodegenerative disorders and other age-related chronic diseases.	19130041
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	Recently, leukotriene-based inflammation has also been shown to play an important role in atherosclerosis: ALOX5AP and LTA4H, both genes in the leukotriene biosynthesis pathway, have individually been shown to be associated with various cardiovascular disease (CVD) phenotypes.	19130089
Inflammation, Primary malignant neoplasm, CARCINOMA OF VULVA, Neoplasms, Chronic infectious disease, Vulva	Altered Intercellular Communication	The relationship existing between inflammation and cancer due to chronic infection, and demonstrated in many solid tumors, led us to study LCs in eight cases of vulvar LS, which showed an evolution to carcinoma of the vulva and in ten cases of unchanged vulvar LS in matched patients by immunohistochemistry for antibodies CD1a and S100.	19130403
MS4A2 wt Allele, Bronchitis	Altered Intercellular Communication	The secondary outcome measures were bronchial inflammation as evaluated by exhaled nitric oxide and atopy as evaluated by skin prick tests.	19131420
Inflammation, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Adiposity and the metabolic syndrome cluster are synergistic in the pathogenesis of inflammation.	19131468
Diabetes Mellitus, Non-alcoholic Fatty Liver Disease, Hepatitis, Cardiovascular Diseases	Altered Intercellular Communication	Systemic and liver inflammation in the high-risk cluster is likely to predict diabetes, cardiovascular disease, and nonalcoholic fatty liver disease.	19131468
Inflammation, Chronic granulomatous disease, Mycoses, Granuloma	Altered Intercellular Communication	Patients with chronic granulomatous disease (CGD) suffer from severe bacterial and fungal infections and deregulated inflammation, which are often associated with granuloma formation.	19131770
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Unexpectedly, histopathologic examination revealed massive acute granulomatous inflammation with liquefied thymic cysts.	19131770
Inflammation, Fever, Abdominal Pain	Altered Intercellular Communication	We report herein the case of a 13-year-old boy with a long history of hectic fevers and abdominal pain, accompanied by stunted growth and elevated biologic markers of inflammation.	19131781
Inflammation	Altered Intercellular Communication	Elderly people with low body weight may have subtle low-grade inflammation.	19131938
Inflammation, Disease	Altered Intercellular Communication	Low-grade inflammation, which plays important roles in the development of fatal diseases, is commonly observed in obese people.	19131938
Extrinsic allergic alveolitis, Cereals, Anterior chamber of eye structure, Vitreous inflammatory cells	Altered Intercellular Communication	A 76-year-old male recently hospitalized for allergic Aspergillus pneumonitis after cleaning out a grain bin presented with reduced vision and anterior chamber and vitreous inflammation.	19132296
Inflammation	Altered Intercellular Communication	The CT criteria for primary EA are a round or oval pericolonic fatty lesion with a hyperattenuated rim and adjacent fat stranding, without other causes of inflammation.	19132488
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	Secondary EA is diagnosed if an epiploic appendage is found to be due to inflammation from other inflammatory entities.	19132488
Inflammation	Altered Intercellular Communication	Occasionally, inflammation of the epiploic appendages is secondary to other inflammatory conditions.	19132488
Inflammation	Altered Intercellular Communication	Occasionally, inflammation of the epiploic appendages is secondary to other inflammatory conditions.	19132488
Keratitis, Scleritis, Myositis, CTCAE 5.0, Episcleritis, Orbital Pseudotumor, Optic Neuritis	Altered Intercellular Communication	The remaining 12.0% of cases showed extrauveal manifestations (scleritis, episcleritis, keratitis, optic neuritis, myositis, and orbital inflammation).	19132784
Inflammation, Blood Clot, Ischemic stroke, Vasospasm	Altered Intercellular Communication	Rho-kinase (ROCK) is a downstream effector of Rho GTPase that is known to regulate various pathological processes important to the development of ischemic stroke, such as thrombus formation, inflammation, and vasospasm.	19133241
Inflammation, Fatigue	Altered Intercellular Communication	Sex differences exist in adiposity, systemic inflammation, physical activity/fitness and fatigue; however, the relations among these variables remain inadequately characterized impeding the development of fatigue prevention strategies.	19133324
Inflammation, Depression, CTCAE, Fatigue	Altered Intercellular Communication	Women report more fatigue than men which was independently associated with inflammation, depression, physical activity and adiposity, whereas in men the only independent predictor was depression.	19133324
Inflammation, Fatigue	Altered Intercellular Communication	Strategies to prevent fatigue may differ in older women and men, especially with regard to inflammation, physical activity and adiposity.	19133324
Pelvic Inflammatory Disease	Altered Intercellular Communication	But the positive rates of CA(125) were 56.1% and 5/8 respectively in endometriotic diseases and pelvic inflammation groups and there were significant differences compared with HE4 (P = 0.000).	19134334
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Synergistic role of inflammation and insulin resistance as coronary artery disease risk factors in African Americans and Caucasians.	19135196
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	The separate roles of inflammation and insulin resistance (IR) in the pathogenesis of cardiovascular disease (CVD) are well recognized.	19135196
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	We investigated whether presence of inflammation would modify coronary artery disease (CAD) risk prediction in subjects with or without IR.	19135196
Inflammation	Altered Intercellular Communication	The results suggest that inflammation may potentiate the cardiovascular risk factor role of IR.	19135196
Inflammation, Thrombosis	Altered Intercellular Communication	Ambient particulate matter has been associated with systemic inflammation indicated by blood markers such as fibrinogen, implicated in promoting atherothrombosis.	19136375
Inflammation, Myopathy, Neuropathy, Neuromuscular Diseases	Altered Intercellular Communication	The underlying lesion was more often a visceral myopathy (22% vs 5%) or neuromyopathy (30% vs 12%) in patients with CIP than in those with ED, whereas the predominant lesion in ED was neuropathy with inflammation.	19136514
Inflammation, Neuropathy, Functional Gastrointestinal Disorders	Altered Intercellular Communication	Neuropathy of enteric ganglia with inflammation seems to be the most common cause for measurable disturbances of intestinal motor function.	19136514
Communicable Diseases, Inflammation	Altered Intercellular Communication	Non specific inflammation formed 19.6% and 25.34% of the smears in the Indian and Mauritian groups, respectively (with specific infection forming 6.05% and 15.08%).	19136776
Cessation of life, Inflammation	Altered Intercellular Communication	Hence, low baseline serum TIBC is associated with iron deficiency, PEW, inflammation, poor QoL and mortality, and its decline over time is independently associated with increased death risk.	19136818
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Inflammation is a key mechanism in human atherosclerotic plaque vulnerability and disruption.	19136823
Fibrous, Inflammation	Altered Intercellular Communication	Fibrous cap inflammation is more likely to occur in noncalcified than in calcified plaques.	19136823
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	In 78.1% histopathologic examination revealed cancer invasion of the vein, whereas the remainder had peritumoral inflammation extending to the vessel wall.	19137380
Inflammation, Keratitis, Ulceration, CTCAE	Altered Intercellular Communication	Amniotic membrane transplantation (AMT) promotes rapid epithelialization and reduces stromal inflammation and ulceration in HSV-1 keratitis.	19138001
Inflammation	Altered Intercellular Communication	The chronic traumatisms may be responsible, especially in well-trained riders, for microhematomas, inflammation, and/or degenerative processes at level of the clitoral structure.	19138367
ARCN1 gene, Bronchitis	Altered Intercellular Communication	Increased oxidative stress and bronchial inflammation are important mechanisms in the pathophysiology of COPD.	19138505
Inflammation	Altered Intercellular Communication	Robust expression of CXCR4/CXCL12 on inflammatory elements in MS lesions highlights a role of this chemokine/receptor pair in central nervous system inflammation.	19139298
Inflammation, Neoplastic disease	Altered Intercellular Communication	Patients with clinical or radiographic evidence of inflammation involving the intraorbital optic nerve and patients with a systemic inflammatory or neoplastic disorder were excluded.	19139343
Inflammation, Fournier Gangrene	Altered Intercellular Communication	The female gender is a risk factor for mortality in patients with Fournier's gangrene and is associated with a higher incidence of inflammation of the retroperitoneal space and abdominal cavity.	19139915
Inflammation, Disseminated Intravascular Coagulation	Altered Intercellular Communication	The authors determined the state of the hemostatic system, the duration of fibrinolysis, intravascular coagulation (IVC) markers, and anticoagulation system activity by the values of antithrombin III (AIII), protein C (PC) and protein S (PS), as well as the depth of systemic inflammation by the values of acute phase reagents.	19140378
Inflammation, Thrombophilia	Altered Intercellular Communication	As systemic inflammation and hypercoagulation syndrome progress, there is a gradual decompensation of the anticoagulation system.	19140378
Inflammation, Thrombophilia	Altered Intercellular Communication	The changes in the values of prothrombin index, AIII, and PC are directly and inversely related to the degree of the hypercoagulation syndrome and systemic inflammation.	19140378
Heart valve calcification	Altered Intercellular Communication	Association of heart valve calcification with malnutrition-inflammation complex syndrome, beta-microglobulin, and carotid intima media thickness in patients on hemodialysis.	19140844
Calcification of mitral valve	Altered Intercellular Communication	Our results suggested the impacts of calcium metabolism and malnutrition-inflammation complex syndrome on valve calcification.	19140844
Inflammation, Malnutrition, diabetic	Altered Intercellular Communication	Difficulty in improving malnutrition and low-grade inflammation in diabetic patients on peritoneal dialysis.	19140846
Inflammation, Demographics Domain	Altered Intercellular Communication	Total weekly creatinine clearance and residual renal function exhibited a rapid decline (P < 0.05) and inflammation parameter levels were higher in DM patients (P < 0.05).	19140846
Inflammation, Necrosis	Altered Intercellular Communication	Clinical findings indicated tumor inflammation and necrosis in most patients.	19140848
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Relapse of the inflammation in the anterior segment of the left eye (LE) resulted in a total closure of the chamber angle and severe glaucoma.	19141146
Nonalcoholic Steatohepatitis, Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Portal chronic inflammation in nonalcoholic fatty liver disease (NAFLD): a histologic marker of advanced NAFLD-Clinicopathologic correlations from the nonalcoholic steatohepatitis clinical research network.	19142989
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Adult nonalcoholic fatty liver disease (NAFLD) is characterized by absent or mild portal chronic inflammation (CI); in children, portal CI may be predominant.	19142989
Inflammation, Steatohepatitis	Altered Intercellular Communication	In both groups, lobular and portal inflammation scores had no association, but there was an association with definite steatohepatitis (P < 0.0001).	19142989
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Increased portal CI is associated with many clinical and pathologic features of progressive NAFLD in both adults and children, but not with ALT, autoantibodies, or lobular inflammation.	19142989
Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	These, and previous findings, point to a vulnerability associated with inflammation and suggest that, even though inflammation may not be the primary cause of neurodegenerative disease, its treatment may decelerate disease progression.	19143652
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Alternatively, the metabolic syndrome is associated with markers of inflammation, such as C-reactive protein (CRP), maybe signalling intraprostatic inflammation.	19143723
Coronary heart disease	Altered Intercellular Communication	T lymphocytes in coronary heart disease in mixed lymphocyte reaction secreted higher levels of pro-inflammation cytokines and lower levels of anti-inflammation cytokines.	19143751
Inflammation, Carcinogenesis, Helicobacter pylori, Chronic gastritis	Altered Intercellular Communication	Inflammation is a key factor in the process of carcinogenesis from chronic gastritis induced by Helicobacter pylori.	19144102
Inflammation, Strongyloides, Ulcerative Colitis	Altered Intercellular Communication	Features of Strongyloides colitis that contrast with those of ulcerative colitis include (1) skip pattern of the inflammation, (2) distal attenuation of the disease, (3) eosinophil-rich infiltrates, (4) relative intact crypt architecture, and (5) frequent involvement of submucosa.	19144377
HD Term Type, Inflammation	Altered Intercellular Communication	In summary, among men treated with HD, testosterone concentrations inversely correlate with all-cause and CVD-related mortality, as well as with markers of inflammation.	19144759
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Depression is common in dialysis patients and is also associated with the presence of chronic inflammation.	19145074
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Mucosal vascular pattern in ulcerative colitis: observations using narrow band imaging colonoscopy with special reference to histologic inflammation.	19145441
Inflammation, cisplatin/mitomycin/vinblastine protocol	Altered Intercellular Communication	The possible correlation between MVP and the histologic grade of inflammation was evaluated.	19145441
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	NBI colonoscopy may be of value for determining the grade of inflammation in patients with quiescent UC.	19145441
Inflammation, Granulomatous Cheilitis, Lip swelling	Altered Intercellular Communication	Cheilitis granulomatosa (CG), which presents clinically as persistent lip swelling, is characterized histologically by noncaseating granulomatous inflammation of unknown origin.	19146041
Inflammation	Altered Intercellular Communication	The pathological changes of the medial aspect of the first metatarsal head of hallux valgus presented extensive chronic inflammation.	19146150
Osteopenia, Chronic systolic heart failure	Altered Intercellular Communication	Bone mineral status and bone loss over time in men with chronic systolic heart failure and their clinical and hormonal determinants.	19147454
Inflammation	Altered Intercellular Communication	However, the oncogenic process in such a context is yet another intriguing example of how chronic inflammation plays an integral role in the tumorigenic process.	19147510
Crohn Disease, Atrophic, Chronic inflammation, Crypt	Altered Intercellular Communication	Histopathological analysis of Crohn's disease samples showed mild or moderate crypt distortion (57.8% and 35.6% of cases), atrophy (6.6%), mild, moderate and marked chronic inflammation (46.7%, 26.7% and 20%), acute inflammatory activity (93.3%), ulceration (24.4%), mucin depletion (37.8%), Paneth's cells (24.4%), intraepithelial lymphocytes (93.3%), and subepithelial collagen (6.7%).	19148357
Crohn Disease, Inflammation	Altered Intercellular Communication	COX-2 immunoexpression is high in Crohn's disease, which suggest a possible role of the protein in the pathogenesis of the inflammation.	19148357
Reinkes edema", Inflammation	Altered Intercellular Communication	Specimens of Reinke's edema were strongly higher in this parameter compared to tumour-free tissue area (p=0.000001), underscoring an association between the level of MMP-9 expression and inflammation.	19148478
Inflammation, Calcification of coronary artery, SLC25A20 gene, Vascular Diseases, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	Because low serum levels of 25-hydroxyvitamin D (25(OH)D) have been associated with many cardiovascular disease (CVD) risk factors, we hypothesized that serum 25(OH)D levels would be inversely associated with inflammation as measured by C-reactive protein (CRP) and with subclinical vascular disease as measured by carotid intimal medial thickness (cIMT) and coronary artery calcification (CAC).	19148561
Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Long-term use of nonsteroidal anti-inflammatory drugs normalizes the kinetics of gastric epithelial cells in patients with Helicobacter pylori infection via attenuation of gastric mucosal inflammation.	19148787
Gastritis	Altered Intercellular Communication	We investigated the effects of NSAIDs on gastric inflammation and the kinetics of gastric epithelial cells in H. pylori-induced gastritis.	19148787
Carcinogenesis, Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	These findings suggest that long-term use of NSAIDs normalizes the kinetics of gastric epithelial cells in patients with H. pylori infection by attenuating gastric mucosal inflammation, which may result in prevention of the gastric carcinogenesis associated with H. pylori infection.	19148787
deficiency aspects, Spasm, Diabetes Mellitus	Altered Intercellular Communication	GABA acts as a neurotransmitter between neurones, while in pancreatic beta cells it plays an integral role in normal insulin secretion, hence the clinical presentation of muscular spasms in SPS and insulin deficiency in diabetes.	19150172
Inflammation, Fever, CTCAE, Cervical lymphadenitis	Altered Intercellular Communication	We report a case of KD in a previously healthy 3-year-old child who presented with acute onset of fever and cervical adenitis, along with computed tomography scan findings of retropharyngeal edema and inflammation.	19150196
Inflammation, Disorder of mineral metabolism, diabetic	Altered Intercellular Communication	to look for differences in clinical characteristics, and differences in the role of mineral metabolism disorders and inflammation in diabetic and non diabetic patients.	19151447
Neurodegenerative Disorders, Inflammation, Nerve Degeneration	Altered Intercellular Communication	The cause of this neurodegeneration has been largely attributed to inflammation, but other mechanisms, including those associated with classic neurodegenerative diseases such as the alpha-synucleinopathies, might also be involved in MS pathogenesis.	19151622
Neuroglia	Altered Intercellular Communication	These data suggest that CD200-mediated immune suppression may occur not only via neuron-microglia interactions, but also via glia-glia interactions, especially in inflammatory conditions in which an immune-suppressive environment needs to be restored; this may occur as a result of increased CD200 expression on reactive astrocytes.	19151626
Inflammation, Peripheral Arterial Diseases, Renal Artery Stenosis	Altered Intercellular Communication	Inflammation and adverse cardiovascular outcome in patients with renal artery stenosis and peripheral artery disease.	19152915
Communicable Diseases, Inflammation	Altered Intercellular Communication	Recent work in biodemography has suggested that lifetime exposure to infection and inflammation may be an important determinant of later-life morbidity and mortality.	19152993
Inflammation	Altered Intercellular Communication	Furthermore, markers of inflammation are known to vary by socioeconomic status in adults and may contribute to overall socioeconomic health inequalities, but little is known about how the sources of this inflammation differ over the life course.	19152993
Refractory anemias, Inflammation, Hypertension, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	We hypothesized altered CECs in patients with RA compared with community controls (CCs) and hospital controls (HCs, with diabetes and hypertension) correlate with established plasma markers of inflammation and of ECD.	19153145
Refractory anemias, Inflammation, Corneal Endothelial Cell Loss	Altered Intercellular Communication	Evidence of endothelial damage in the form of mildly increased numbers of CECs is present in RA and is independent of plasma markers of inflammation and of ECD.	19153145
Communicable Diseases, Inflammation, Hypersensitivity, Failure (biologic function)	Altered Intercellular Communication	Failure to remove foreign bodies is likely to give rise to acute or late complications, such as allergies, inflammation or infection, that may be severe.	19153745
Inflammation, Periprosthetic Fractures	Altered Intercellular Communication	Our results demonstrate that oral EM reduces the inflammation of periprosthetic tissues, as manifested by the reduction of the numbers of infiltrating cells, CD68+ macrophages, RANKL+ cells, and TRAP+ cells.	19154802
Inflammation, Myocardial dysfunction, Congestive heart failure	Altered Intercellular Communication	There were significant correlations between natriuretic peptides and markers of inflammation and myocardial dysfunction in CHF patients: BNP vs. TNF (r=0.64, p=0.0006), vs. LVEDD (r=0.59, p=0.0025); ANP vs. TNF (r=0.60, p=0.0016), vs. LVEDD (r=0.65, p=0.0006); TNF vs. LVEDD (r=0.57, p=0.004).	19155075
Inflammation	Altered Intercellular Communication	In summary, we propose that before disease onset, strong genetic factors associated with disease risk dictate sIL-2RA levels that may be further modulated with onset of chronic systemic inflammation associated with MS.	19155502
Atherosclerosis	Altered Intercellular Communication	To explore the role of invasion of P. gingivalis in inflammation- and infection-associated atherosclerosis, 10-wk-old ApoE(+/-) mice were fed either a high fat diet or a regular chow diet.	19155507
Symptoms, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms.	19155537
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Here we investigate Trp catabolism, IDO activity and the role of inflammation in moderate to very severe CKD and haemodialysis.	19155537
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	In CKD, induction of IDO may primarily be a consequence of chronic inflammation.	19155537
Tympanoplasty, Inflammation, Cholesteatoma	Altered Intercellular Communication	Six weeks after admission the patient underwent mastoidectomy and tympanoplasty to cure the cholesteatoma and prevent recurrence of inflammation.	19155571
Inflammation, Chronic thyroiditis, Breast Carcinoma	Altered Intercellular Communication	Diffuse thyroid uptake on PET-CT represents active inflammation caused by chronic thyroiditis in patients with advanced breast carcinoma.	19156410
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Gleason score, the number of positive cores, maximum percent of cancer and inflammation were considered on biopsy.	19157433
Acute and chronic inflammation	Altered Intercellular Communication	The mucosal addressin cell adhesion molecule 1/integrin alpha(4)beta(7) pathway is involved in the pathogenesis of chronic intestinal inflammation by recruiting lymphocytes into inflamed gut.	19157500
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Peroxisome proliferator-activated receptors regulate lipid metabolism, affecting inflammation and cancer.	19157507
Inflammation, Diabetic Retinopathy, Uveitis	Altered Intercellular Communication	Inflammation is a major contributing factor to many blinding disorders including uveitis, diabetic retinopathy, and age-related macular degeneration.	19157552
Inflammation, Swelling, Pain Distress Question	Altered Intercellular Communication	There was no significant relationship between the grades of inflammation of the sialographic images with swelling or pain.	19157917
ARCN1 gene, Inflammation	Altered Intercellular Communication	Reduced activity of histone deacetylases (HDAC) contributes to enhanced inflammation in stable COPD.	19158122
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Dietary (n-3) PUFA reduce inflammation, an independent risk factor for cardiovascular disease.	19158225
palladium, Inflammation	Altered Intercellular Communication	In conclusion, upregulation of COX-2 during EMT may mediate peritoneal inflammation, suggesting COX-2 inhibition as a potential strategy to ameliorate peritoneal deterioration in PD patients.	19158357
Inflammation	Altered Intercellular Communication	Inflammation may have a role in the pathogenesis of CCh.	19158563
Inflammation	Altered Intercellular Communication	Markers for inflammation are more pronounced in the advanced stages of this disease.	19158563
Nonulcer dyspepsia	Altered Intercellular Communication	Does Helicobacter pylori-induced inflammation of gastric mucosa determine the severity of symptoms in functional dyspepsia?	19159074
Nonulcer dyspepsia	Altered Intercellular Communication	In this study, we aimed to investigate the relationship among the severity of symptoms, oxidative stress, and grading scales of Helicobacter pylori-induced gastric inflammation in functional dyspepsia.	19159074
Inflammation, Gastritis	Altered Intercellular Communication	Although there was no statistically significant relationship between symptom scores and degree of chronic inflammation, a tendency for symptoms to be more severe has been observed in low levels of gastritis.	19159074
Inflammation, Helicobacter pylori	Altered Intercellular Communication	Levels of sulfhydryl groups were lower in subjects with high levels of chronic inflammation, and Helicobacter pylori intensity (P < 0.001 and P = 0.02, respectively).	19159074
Inflammation	Altered Intercellular Communication	Levels of malondialdehyde were higher in subjects with high levels of chronic inflammation (P = 0.04).	19159074
Nonulcer dyspepsia, Helicobacter pylori, Gastritis	Altered Intercellular Communication	In conclusion, there may be an inverse relation between severity of symptoms and level of Helicobacter pylori induced gastric inflammation or oxidative stress in patients with functional dyspepsia.	19159074
Airway structure, Inflammation, Asthma	Altered Intercellular Communication	Increase of serum ECP level is an important indicator of airway inflammation activity and inflammation serious degree in the bronchial asthma patients.	19159574
Onychomycosis, Glossitis	Altered Intercellular Communication	Three of them had associated fingernail onychomycosis with periungual inflammation.	19160539
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Myeloperoxidase levels were shown to reflect endothelial dysfunction, inflammation, atherosclerosis and oxidative stress.	19160948
Inflammation, Primary malignant neoplasm, Carcinoma of lung, Pneumonitis, Pleural Effusion, CTCAE	Altered Intercellular Communication	The 320-kDa and 280-kDa FN forms as well as FN fragments appeared in the pleural effusion and plasma of patients suffering from lung inflammation or cancer in significantly higher relative amounts in both lung cancer groups than in the inflammation.	19161998
Inflammation	Altered Intercellular Communication	These findings suggest that while broad group differences between genders and races/ethnicities exist, personality represents an important source of individual differences in inflammation within groups.	19162168
Inflammation	Altered Intercellular Communication	The calcium content of the aortic valve was measured and valvular inflammation was quantified.	19162347
Inflammation	Altered Intercellular Communication	On the other hand, older patients with AS had higher plasma level of resistin which was associated with the degree of valvular calcification and inflammation.	19162347
Decompensation, Inflammation	Altered Intercellular Communication	Also, patient receipt of RNA testing becomes dependent on clinical cues of hepatic decompensation or inflammation.	19162434
Inflammation	Altered Intercellular Communication	Antioxidant status of patients on peritoneal dialysis: associations with inflammation and glycoxidative stress.	19164258
palladium, glycation, Hypernatremia, Inflammation	Altered Intercellular Communication	Patients on peritoneal dialysis (PD) frequently exhibit oxidant-antioxidant imbalance, advanced glycation end-product overload, and subclinical inflammation but the interrelations between these pathophysiological changes have not been fully elucidated.	19164258
Airway structure	Altered Intercellular Communication	Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice.	19164702
Cessation of life, vascular inflammations, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	We examined associations of pentraxin 3 (PTX3), a vascular inflammation marker, with incident cardiovascular disease (CVD) and all-cause death.	19164811
Cessation of life, Inflammation	Altered Intercellular Communication	PTX3 likely reflects different aspects of inflammation than CRP and may provide insight into vascular health in aging and chronic diseases of aging that lead to death.	19164811
Burn Specimen Source Codes, Inflammation	Altered Intercellular Communication	Acute inflammation is persistent locally in burn wounds: a pivotal role for complement and C-reactive protein.	19165117
Inflammation, Traumatic injury	Altered Intercellular Communication	The excessive presence of the inflammatory mediators, complement and CRP, and the increased infiltration of neutrophils and macrophages in burn wounds up to 46 days after injury implicate a persistent ongoing acute inflammation locally in the burn wound up to weeks after the initial trauma.	19165117
Inflammation, Obesity	Altered Intercellular Communication	A growing body of evidence has consistently shown a correlation between obesity and chronic subclinical inflammation.	19165157
Inflammation	Altered Intercellular Communication	Thigh intermuscular fat had an inconsistent but significant association with inflammation, and there was a trend toward lower inflammatory marker concentration with increasing thigh subcutaneous fat in white and black women.	19165157
Inflammation	Altered Intercellular Communication	The gallbladder was straightened and then removed without difficulty because there was only slight inflammation around Calot's triangle and the gallbladder was not fixed to the liver.	19165413
Inflammation, Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Type of mucosa, Helicobacter pylori infection, inflammation, mucosal proliferative activity, p53 and p21 expression, and relations to gastritis.	19165597
Inflammation, Carditis, Gastritis, Cardia of stomach	Altered Intercellular Communication	In subjects with cardia-type mucosa, and both carditis and gastritis, the degree of chronic inflammation was higher in the cardia compared to the corpus and antrum and the p53 expression was significantly higher in the cardia compared to the corpus, but similar to that in the antrum.	19165597
Inflammation, Nasal Polyps, Hyperplasia, IL13 gene	Altered Intercellular Communication	(1) Hematoxylin and eosin staining showed that there was obvious inflammation reaction, a large quantity of glands hyperplasia and acidophils soaked in nasal polyps, especially those with allergic rhinitis.	19166033
Inflammation, Cardiac function, Endothelial dysfunction	Altered Intercellular Communication	We found evidence of participation of proinflammatory factors in pathogenesis of HF and established associations of mediators of inflammation (CRP, IL-8) with severity of HF, endothelial dysfunction, and impairment of cardiac function.	19166394
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Helicobacter pylori infection is associated with development of chronic inflammation and infiltration of immune cells into the gastric mucosa.	19166415
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	Many studies have suggested that inflammation may participate in the pathogenesis of non-valvular atrial fibrillation (AF).	19167648
inflammation or infection	Altered Intercellular Communication	Our results implied that an infectious inflammation may participate in the pathogenesis of non-valvular AF.	19167648
Communicable Diseases, Inflammation	Altered Intercellular Communication	Dialysate effluent leukocytosis is consistent with a greater degree of infection or inflammation in patients receiving peritoneal dialysis.	19167800
Inflammation, Torsades de Pointes, Ventricular Fibrillation	Altered Intercellular Communication	Although antibiotic treatment led to a decrease of inflammation parameters and decrease of the pulmonary infiltrate the patient died due to development of torsades de pointes tachycardia leading to ventricular fibrillation and hypoxic brain damage.	19167851
ARCN1 gene, Lung Diseases, Obstructive, Airway structure	Altered Intercellular Communication	Neutrophilic asthma and COPD are obstructive airway diseases common in older age and have a characteristic airway inflammation with neutrophilic bronchitis.	19168339
Inflammation, Congestive heart failure	Altered Intercellular Communication	We investigated the correlation between health status and inflammation burden as well as its long-term prognostic value in CHF outpatients.	19168514
Refractory anemias, Inflammation	Altered Intercellular Communication	Our findings demonstrate that SC5b-9 induces OPG production by endothelial cells and we propose that the SC5b-9-mediated up-regulation of OPG may be an important mechanism whereby complement contributes in promoting and/or enhancing the inflammation in RA.	19168833
Airway structure	Altered Intercellular Communication	We suggest that the daily highest PEF under good control is not a substitute for best PEF because it changes according to the degree of improvement of airway inflammation.	19169083
Sepsis, Inflammation, Thrombosis, Community acquired pneumonia	Altered Intercellular Communication	Biomarkers of thrombosis, fibrinolysis, and inflammation in patients with severe sepsis due to community-acquired pneumonia with and without Streptococcus pneumoniae.	19169631
Sepsis, Inflammation, Thrombosis	Altered Intercellular Communication	In this population of patients with severe sepsis, patients with S. pneum CAP had a more severe dysregulation of coagulation, fibrinolysis, and inflammation than patients with non-S. pneum CAP; the former also developed significantly elevated levels of markers of thrombosis.	19169631
Inflammation, Carcinogenesis	Altered Intercellular Communication	Both, chronic inflammation and an increased cell proliferation are considered to play an important role in colon carcinogenesis.	19169726
Disease, Obesity	Altered Intercellular Communication	Obesity is a chronic sub-inflammatory condition which is a risk factor for several cancer diseases, e.g.	19169726
Dacryoadenitis, Ulcerative Colitis	Altered Intercellular Communication	Case of lacrimal gland inflammation associated with ulcerative colitis.	19169863
Dacryoadenitis, Pseudotumor	Altered Intercellular Communication	Intravenous administration of prednisolone was initiated on suspicion of lacrimal gland inflammation (pseudotumor).	19169863
Granulomatous Mastitis, Exanthema, Necrotizing granulomatous inflammation, Lymphadenopathy, Uveitis, Arthritis	Altered Intercellular Communication	The proband's first son had exanthema, arthritis, and uveitis from 10 years of age and later presented with granulomatous lymphadenopathy, granulomatous parotitis, and granulomatous intestinal inflammation.	19169908
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Systemic inflammation concomitant with prevailing MetS might turn apoA-I into proinflammatory particles.	19171400
Cardiovascular system	Altered Intercellular Communication	However, after multivariate adjustment for demographics (case mix) and surrogates of malnutrition-inflammation complex, higher weight-gain increments were associated with increased risk of all-cause and cardiovascular death.	19171851
Inflammation, Neurogenic Inflammation, Upper Respiratory Infections, Cognition Disorders	Altered Intercellular Communication	Mexico City (MC) children exposed to significant concentrations of air pollutants exhibit chronic respiratory inflammation, systemic inflammation, neuroinflammation, and cognitive deficits.	19171930
Inflammation	Altered Intercellular Communication	Exposure to urban air pollution is associated with immunodysregulation and systemic inflammation in children and is a major health threat.	19171930
Inflammation	Altered Intercellular Communication	We intended to draw attention to frequently occurring scrotal inflammation and thus the underlying diseases.	19172112
Inflammation, Chlamydia	Altered Intercellular Communication	Chlamydia pneumoniae can possibly trigger and maintain inflammation in coronary arteries.	19172436
Single organ dysfunction, Inflammation, Thrombosis	Altered Intercellular Communication	Platelet activation contributes to microvascular thrombosis and organ failure in systemic inflammation.	19172522
Single organ dysfunction, Inflammation	Altered Intercellular Communication	According to our data a possible benefit of anti-platelet drugs in patients on risk for systemic inflammation and organ failure should be tested in a prospective trial.	19172522
Inflammation, Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	According to the Rome criteria, macroscopic and histological inflammation is a crucial exclusion criterion for IBS.	19174795
Ulcerative Colitis	Altered Intercellular Communication	Recent results imply that HBD-2 is expressed in active intestinal inflammation, especially in ulcerative colitis (UC).	19174795
Inflammation, Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	The results support an activation of the mucosal innate defense system toward a proinflammatory response in IBS patients in the absence of macroscopic signs of inflammation.	19174795
Inflammation, Muscle (organ)	Altered Intercellular Communication	It has been suggested that serum cystatin C is less influenced by sex, body size, muscular mass or inflammation.	19175073
Inflammation, Thrombosis, Postthrombotic Syndrome	Altered Intercellular Communication	Inflammation in deep vein thrombosis and the development of post-thrombotic syndrome: a prospective study.	19175493
Inflammation, Blood Clot, Budd-Chiari Syndrome	Altered Intercellular Communication	The results of this study suggest that inflammation might play a role in incomplete thrombus clearance, venous outflow obstruction and the development of PTS after 1 year.	19175493
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Diagnosis of ulcerative colitis before onset of inflammation by multivariate modeling of genome-wide gene expression data.	19177426
Crohn Disease, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Endoscopically obtained mucosal biopsies play an important role in the differential diagnosis between ulcerative colitis (UC) and Crohn's disease (CD), but in some cases where neither macroscopic nor microscopic signs of inflammation are present the biopsies provide only inconclusive information.	19177426
Inflammation, Fibrosis Assessment, Hepatitis C	Altered Intercellular Communication	Only liver biopsy allows a reliable evaluation of the course of hepatitis C by grading inflammation and staging fibrosis, and thus serum biomarkers for hepatic fibrosis with high sensitivity and specificity are needed.	19177598
Inflammation, Acute Coronary Syndrome, Atherosclerosis, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Association of plasma visfatin levels with inflammation, atherosclerosis and acute coronary syndromes (ACS) in humans.	19178507
Inflammation, Acute Coronary Syndrome, Atherosclerosis, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	We sought to assess whether plasma visfatin level is independently associated with inflammation, atherosclerosis and acute coronary syndromes (ACS).	19178507
Inflammation, Atherosclerosis, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	The association of visfatin with risk factors, inflammation, atherosclerosis, and ACS was determined.	19178507
Chronic Kidney Diseases	Altered Intercellular Communication	Sex steroid hormones may play a role in the pathogenesis of chronic kidney disease (CKD).	19178534
Inflammation	Altered Intercellular Communication	Novel polymorphism of interleukin-18 associated with greater inflammation after cardiac surgery.	19178691
Inflammation	Altered Intercellular Communication	The TT genotype of the IL-18 9545 T/G polymorphism is associated with an increased occurrence of prolonged ICU stay post-surgery and greater post-surgical inflammation.	19178691
Inflammation	Altered Intercellular Communication	OB volume correlated with the SND score, which is an indicator of the degree of sinonasal inflammation.	19178796
Inflammation	Altered Intercellular Communication	Pathological slides were graded by a pathologist to characterize the degree of inflammation and SM, when present.	19178797
Inflammation	Altered Intercellular Communication	Histological grading of chronic inflammation showed significantly greater severity in specimens with SM (n = 16) when compared with the cohort without SM (n = 75; 100.0% versus 77.5%, respectively; p = 0.016).	19178797
Chronicity, Inflammation	Altered Intercellular Communication	It has a positive correlation with the severity of inflammation noted histologically in CRS but does not correlate with disease severity or chronicity, clinically.	19178797
Inflammation	Altered Intercellular Communication	In patients with chronically diseased maxillary sinuses, poor mucociliary clearance may result from long-standing inflammation or scarring from previous surgery.	19178809
Perifolliculitis	Altered Intercellular Communication	In children aged 1-9 years percentage decline, by district, for outcomes was: 32% (95% CI 19-48) to 88% (95% CI 83-91) for trachomatous inflammation-follicular (TF); 87% (95% CI 83-91) to 99% (95% CI 97-100) for trachomatous inflammation-intense (TI); and 31% increase (95% CI -42 to -19) to 89% decrease (95% CI 85-93) for unclean face; and in adults percentage decline in trichiasis was 45% (95% CI -13 to 78) to 92% (95% CI 78-96).	19178920
Inflammation, Thrombus	Altered Intercellular Communication	We studied the correlation between inflammation and the risk of thrombogenesis in patients with AF and the relationship of inflammation with other factors associated with thrombotic risk.	19178964
Inflammation, Blood Stasis	Altered Intercellular Communication	Thus, blood stasis and inflammation appear to constitute two major distinct components of thrombogenesis.	19178964
Inflammation	Altered Intercellular Communication	Intraarticular application of a combined short-acting + long acting agent is suggested exclusively in cases of visible and laboratory signs of inflammation that are limited to a few joints.	19179257
Inflammation, Angina, Unstable, Diabetes Mellitus, Coronary Artery Disease, Cessation of life	Altered Intercellular Communication	Our study suggests that different pathophysiological mechanisms may be responsible for MI and death in unstable angina patients with or without diabetes and that severity of coronary artery disease plays a major role in diabetes (and inflammation in the absence of diabetes).	19179271
ARCN1 gene, Inflammation	Altered Intercellular Communication	To test the hypothesis that patients with COPD experience accelerated telomere shortening and that inflammation is linked to this process.	19179485
Minimal Disseminated Disease, Fracture, Unipolar Depression	Altered Intercellular Communication	Further research is needed to determine if individuals with major depressive disorder (MDD) are at higher fracture risk and whether neuroendocrine or hormonal dysregulation might contribute to such risk in MDD.	19179844
Hepatic inflammation	Altered Intercellular Communication	Improvements in markers of hepatic inflammation as well as nutritional status also were noted in these patients.	19179884
Inflammation, SYNOVITIS, GRANULOMATOUS, WITH UVEITIS AND CRANIAL NEUROPATHIES (disorder)	Altered Intercellular Communication	The aim of this study was to test the hypothesis that IL-1beta may mediate the inflammation seen in patients with Blau syndrome.	19180500
Inflammation, Hepatitis, Necrosis	Altered Intercellular Communication	Histopathology showed various degrees of intralobular inflammation, necrosis, involvement of the small bile ducts, and in one case interface hepatitis; but in general, histopathology did not reveal a common pathogenetic mechanism.	19182681
Inflammation	Altered Intercellular Communication	An inflammation of the gingiva could be verified because of the existence of inflammatory cells.	19182870
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation, characterized by the recruitment and adhesion of circulating leukocytes by cellular adhesion molecules, plays an important role in the pathogenesis of atherosclerosis.	19183069
Inflammation	Altered Intercellular Communication	The main UAIM pathology may be outer retinal layer and retinal pigment epithelial inflammation.	19183855
Choroiditis	Altered Intercellular Communication	FA, IA, and OCT suggested that choroidal inflammation may be involved in the pathogenesis of UAIM.	19183855
Inflammation, Neoplasms	Altered Intercellular Communication	Tumor cell expression of TLRs can promote inflammation and cell survival in the tumor microenvironment.	19184006
Inflammation	Altered Intercellular Communication	With increasing inflammation, the intensities of the peak resonance at 1.3 ppm increased and that at 3.8 ppm decreased.	19184029
Inflammation	Altered Intercellular Communication	Specific MR spectral features reflect the anaerobic metabolism that is evident with progressively increasing degrees of RA synovial inflammation and vascularity.	19184029
Inflammation, Crohn Disease	Altered Intercellular Communication	Endoscopic bowel wall biopsy specimens were assessed using a self-developed inflammation score and the disease activity was calculated using Crohn's disease activity index (CDAI).	19184036
Celiac Disease, Autoimmune enteropathy	Altered Intercellular Communication	Coeliac disease is an autoimmune enteropathy characterised by chronic inflammation of the small intestinal mucosa and the presence of typical autoantibodies.	19184116
Inflammation, Fournier Gangrene	Altered Intercellular Communication	Fournier's gangrene is a fulminant and destructive inflammation of the scrotum, penis, and perineum.	19185110
Inflammation	Altered Intercellular Communication	These findings suggest that inhibition of systemic inflammation may be a mechanism by which n-3 fatty acids prevent recurrent cardiovascular events.	19185299
Gingivitis, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus	Altered Intercellular Communication	The goal of this study was to assess whether non-smoking patients with type 2 diabetes present with increased levels of local and systemic proinflammatory mediators and, if so, whether such an increase is associated with enhanced clinical gingival inflammation compared to non-smoking patients without diabetes.	19186972
Gingivitis, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Furthermore, systemic inflammation, as demonstrated by the increased level of serum IL-6, is associated with BGI gingivitis among non-smoking patients with diabetes.	19186972
Inflammation, Cortical Dysplasia, Neoplasms	Altered Intercellular Communication	Seizure-induced inflammation in focal cortical dysplasia resulting in imaging progression that simulates neoplasia.	19187476
Seizures, Inflammation, Fleck corneal dystrophy	Altered Intercellular Communication	We propose that chronic inflammation was induced by unremitting seizure activity and suggest that inflammation may be implicated as a basis for alteration in the imaging characteristics of FCD.	19187476
Unexpected Adverse Event, Inflammation, Atherosclerosis	Altered Intercellular Communication	Serum high sensitive C-reactive protein (hs-CRP), adiponectin levels and urine albumin excretion rate (UAER) are probably associated with inflammation and atherosclerosis.	19187587
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	In patients with suspected sarcoidosis, the smaller ultrasound needle may yield inadequate material to make a histologic diagnosis of granulomatous inflammation.	19188547
Inflammation, Atrophic, Malignant Neoplasms	Altered Intercellular Communication	Neuroendocrine cells may be induced under conditions of atrophy with or without chronic inflammation in both noncancerous glands and in cancers, including calcitonin-positive cells.	19188748
Carcinogenesis	Altered Intercellular Communication	omega-6 and omega-3 polyunsaturated fatty acids intakes may play opposing roles in inflammation-driven colorectal carcinogenesis.	19190143
Inflammation, Ductal Breast Hyperplasia	Altered Intercellular Communication	These findings suggest that systemic inflammation may affect breast epithelial neoplasia.	19190628
Inflammation, Thrombophilia	Altered Intercellular Communication	A comparative analysis between the prevalence of PE and risk factors (number of days per week with lipophilic content of the TPN, bowel inflammation and thrombophilic factors (protein C and S) was performed.	19190906
allergic inflammation	Altered Intercellular Communication	Leptin and adiponectin produced by fat tissues play a critical role in the regulation of body weight and allergic inflammation.	19191139
Inflammation	Altered Intercellular Communication	Loss of collecting venules, or both collecting and capillary structures was correlated with chronic inflammation and activity.	19191891
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Only in males, not in females, the H. pylori infection and its related acute and chronic inflammation scores were significantly associated with a lower ghrelin level (p < or = .04).	19191897
Inflammation	Altered Intercellular Communication	Our results provided additional evidence that alterations in the expression of survivin and Hsp90 in oral epithelia might be associated with pathological stress, such as chronic inflammation, in patients with OLP.	19192050
Inflammation, Fibrosis Assessment, Muscular Atrophy, Muscle hypertrophy	Altered Intercellular Communication	The histopathologic findings allowed for categorization into 5 groups: group 1, normal ureteral tissue; group 2, chronic inflammation; group 3, smooth muscle hypertrophy, group 4, fibrosis; and group 5, smooth muscle atrophy.	19193425
Inflammation	Altered Intercellular Communication	In the group without crossing vessels, chronic inflammation (40%) was the predominant histologic findings.	19193425
Delirium, Inflammation, Dehydration	Altered Intercellular Communication	The most frequent causes of delirium were opioids (29%), inflammation (27%), dehydration and/or sodium level abnormalities (15%).	19193654
Inflammation, Hemorrhage, Cecal mass	Altered Intercellular Communication	Xanthogranulomatous inflammation of the colon: a rare cause of cecal mass with bleeding.	19194269
Inflammation	Altered Intercellular Communication	Xanthogranulomatous inflammation is a well-defined disease most frequently reported in the kidney and gallbladder.	19194269
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Fatty degeneration	Altered Intercellular Communication	NAFLD was classified according to the Matteoni types: type I: steatosis alone; type II: steatosis with inflammation; types III-IV: steatosis with ballooning and/or fibrosis.	19194305
Bile Duct Neoplasms, Eosinophilic cholangitis, Malignant Neoplasms	Altered Intercellular Communication	Eosinophilic cholangitis, a rare inflammatory condition that clinically resembles a biliary malignancy, should be taken into consideration in the differential diagnosis in the evaluation of presumed neoplasm of the bile ducts.	19194647
Pain Distress Question, Exophthalmos, Swelling of eyelid, Inflammation	Altered Intercellular Communication	Inflammatory eye signs, for example, pain and pressure sensation, caruncle inflammation, eyelid swelling, and exophthalmos decreased significantly.	19194836
Inflammation, Retinitis	Altered Intercellular Communication	An unexplained sudden decrease in endothelial cell count (ECC) in the absence of rejection or significant inflammation was seen in 3 patients, whereas 1 patient also developed concomitant retinitis.	19195708
Inflammation, Chronic congestive heart failure, Congestive heart failure	Altered Intercellular Communication	Chronic congestive heart failure (CHF) is associated with an increase in cytokines and inflammatory markers, particularly in elderly patients in whom chronic inflammation is generally present per se.	19196011
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	The role of sex and biochemical markers of inflammation in left ventricular remodelling, before and after surgery, in elderly patients with aortic valve stenosis.	19196618
Inflammation	Altered Intercellular Communication	Chronic inflammation is associated with low physical function in older adults across multiple comorbidities.	19196644
Inflammation	Altered Intercellular Communication	Chronic subclinical inflammation may contribute to impaired physical function in older adults; however, more data are needed to determine whether inflammation is a common mechanism for functional decline, independent of disease or health status.	19196644
Inflammation	Altered Intercellular Communication	Chronic subclinical inflammation may be a marker of functional limitations in older persons across several diseases/health conditions.	19196644
Degenerative polyarthritis, Inflammation, Obesity	Altered Intercellular Communication	These findings emphasize the need to further investigate the potential pathogenic role of obesity and low-grade inflammation in OA and underscore the importance of obesity prevention to avoid early prosthetic replacement of the hip.	19197252
Inflammation	Altered Intercellular Communication	African-American women consistently displayed greater inflammation compared with whites, even after controlling for VAT or SAT.	19197255
Vitreous haze, Intraocular inflammation, Vasculitis	Altered Intercellular Communication	Ocular examination revealed a substantial intraocular inflammation causing a dense vitreous haze and frosted branch angiitis.	19198761
Intraocular inflammation, Virulizin	Altered Intercellular Communication	A review of the literature led us to propose that our patient developed an intraocular inflammation which may probably be a form of IRU and it might be appropriate to employ additional criteria in the definition and the diagnosis of IRU.	19198761
Inflammation, Periodontitis, Osage language, Cardiovascular morbidity, Sleep Apnea, Obstructive	Altered Intercellular Communication	Since both obstructive sleep apnoea (OSA) and periodontitis are associated with systemic inflammation and cardiovascular morbidity, we questioned whether there may be an association between these two disorders.	19198909
Sarcoma, Inflammation, Neoplasms, Giant cell sarcoma	Altered Intercellular Communication	To further characterize these aberrations, we have investigated eight soft tissue sarcomas diagnosed as MIFS, haemosiderotic fibrolipomatous tumour (HFT), myxoid spindle cell/pleomorphic sarcoma with MIFS features, and inflammatory malignant fibrous histiocytoma/undifferentiated pleomorphic sarcoma with prominent inflammation (IMFH) harbouring a t(1;10) or variants thereof and/or ring chromosomes with possible involvement of chromosome 3.	19199331
Inflammation, Edema	Altered Intercellular Communication	The authors hypothesize that leakage of the drug across a locally impaired blood-brain barrier contributes to peritumoral edema and inflammation, which may be erroneously interpreted as disease progression.	19199506
Inflammation, Balanoposthitis, Balanitis	Altered Intercellular Communication	Balanitis is defined as inflammation of the glans penis, often involving the prepuce (balanoposthitis).	19200183
Coinfection, Noncommunicable Diseases, Have Autoimmune or Inflammatory Condition, Malignant Neoplasms, Fever of Unknown Origin, Immune System Diseases	Altered Intercellular Communication	The cause of FUO was explained according to the PET/CT findings and followed investigations in 44 of 48 cases-18 cases of microbial infections, nine cases of autoimmune inflammations, four cases of non-infectious granulomatous diseases, eight cases of malignancies and five cases of proved immunity disorders were found.	19201122
Orthodontic, Inflammation	Altered Intercellular Communication	Previous research has shown that inflammation is a major part of the biologic response to orthodontic forces.	19201330
Tissue damage, Inflammation	Altered Intercellular Communication	In inflammation, signal molecules that originate in remote diseased organs can reach strained paradental tissues and exacerbate the inflammatory process, leading to tissue damage.	19201330
Airway structure	Altered Intercellular Communication	Asthma is frequent in elite athletes and clinical studies in athletes have found increased airway inflammation.	19201767
Airway structure, Asthma	Altered Intercellular Communication	To investigate asthma-like symptoms, airway inflammation, airway reactivity (AR) to mannitol and use of asthma medication in Danish elite athletes.	19201767
Inflammation, Myometritis, Infection	Altered Intercellular Communication	As a diffuse chronic inflammation, myometritis is very rare and usually follows after postpartal placenta remains or postabortion infections, but it can be also associated with endometrial or ascendent infection.	19203072
Hepatitis, Hepatitis B, Chronic, Necrosis	Altered Intercellular Communication	[Estimation of liver inflammation and necrosis in patients with chronic hepatitis B through different biochemical items].	19203444
Hepatitis, Hepatitis B, Chronic, Necrosis	Altered Intercellular Communication	To establish a new grading system to evaluate liver inflammation and necrosis in patients with chronic hepatitis B through clinical biochemical assays.	19203444
Hepatitis, Necrosis	Altered Intercellular Communication	The extent of liver inflammation and necrosis was evaluated according to the total score.	19203444
Hepatitis, Necrosis	Altered Intercellular Communication	The grade of liver inflammation and necrosis was considered less than 2.0 if total score lower than 6, and higher grade was considered with higher total score.	19203444
Hepatitis, Necrosis	Altered Intercellular Communication	The estimated results shared an identity of 82.8% with the real grades of liver inflammation and necrosis.	19203444
Hepatitis, Necrosis	Altered Intercellular Communication	When this grading system was applied to patients with liver inflammation and necrosis equal to or higher than grade 2.0, it exhibited a sensitivity of 83.8%, a specificity of 81.2%, a positive prediction value of 88.6%, a negative prediction value of 74.2% in all cases, and 88.0%, 84.7%, 90.6%, 82.4% respectively in patients older than 12 years.	19203444
Hepatitis, Chronic, Hepatitis, Necrosis	Altered Intercellular Communication	Our data suggest that the grading system can be used to evaluate the extent of liver inflammation and necrosis in patients with chronic hepatitis B.	19203444
Inflammation, Hepatitis C, Atherosclerosis	Altered Intercellular Communication	Hepatitis C virus infection in hemodialysis patients is not associated with insulin resistance, inflammation and atherosclerosis.	19203507
Inflammation, Malnutrition, Atherosclerosis, Depression, CTCAE, Cardiovascular system	Altered Intercellular Communication	In conclusion, because of the close association of depression with inflammation, malnutrition, and cardiovascular mortality, it could be speculated that depression is one branch of the MIA (malnutrition, inflammation, atherosclerosis) syndrome.	19203509
Inflammation, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	Obstructive sleep apnea (OSA) is associated with severe cardiac stress and systemic inflammation.	19203550
Cardiovascular stress testing, Inflammation, Abnormal breathing	Altered Intercellular Communication	In this pilot study, both parameters suggest an important role of sleep related breathing disorders on cardiac stress and chronic inflammation.	19203550
Inflammation, Photophobia, Pain Distress Question	Altered Intercellular Communication	Inflammation was assessed by the presence of cells in the anterior chamber, anterior chamber flare, ciliary flush, photophobia and pain.	19203564
Pneumonitis, Impaired	Altered Intercellular Communication	Postnatal steroid use decreases lung inflammation but increases impairment.	19204058
Inflammation, Neoplasms, Necrosis, Orbital Pseudotumor, Orbital Cellulitis, Endophthalmitis, CTCAE	Altered Intercellular Communication	Inflammation caused by necrosis of the tumor and other ocular tissues led to misdiagnosis as endophthalmitis, orbital cellulitis, or idiopathic orbital inflammation in several cases.	19204229
Inflammation, Failure (biologic function), Tumor Necrosis Factors	Altered Intercellular Communication	Necrosis-related inflammation can confound the clinical diagnosis of occult lesions, as can failure of necrotic tumors to enhance on imaging studies.	19204229
Intraocular inflammation, Foveal atrophy	Altered Intercellular Communication	Foveal atrophy can be a complication of intraocular inflammation in a variety of uveitic syndromes.	19204236
Inflammation, Obesity	Altered Intercellular Communication	The association between inflammation and obesity is well documented; however, there is little evidence linking physiological markers of inflammation and psychosocial factors such as body image.	19204727
Inflammation, Acute onset pain, Necrosis	Altered Intercellular Communication	It manifests as acute pain, cutaneous, subcutaneous and intra-muscular inflammation and necrosis immediately following an injection, with potentially devastating sequelae.	19205337
Inflammation, Hydrocephalus, Epilepsy	Altered Intercellular Communication	In 3/32 epilepsy occured in the course of hydrocephalus and in 3/32 children as one of CNS inflammation complications.	19205354
Inflammation	Altered Intercellular Communication	Although uncommon, pelvic masses that are benign may mimic malignant masses with extradnexal inflammation.	19205445
Airway structure, Inflammation, physiopathological, Cystic Fibrosis	Altered Intercellular Communication	Can skeletal muscle function and efficiency be measured during exercise non-invasively using respiratory mass spectrometry (RMS); and is the known exercise dysfunction in cystic fibrosis (CF) children related in part to a disease specific defect of skeletal muscle, or a non-specific manifestation of chronic airway infection and inflammation.	19206180
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Numerous 4- to 20-mum round vacuoles were present throughout the reticular dermis associated with focal fibrosis, interstitial mucin, and little surrounding inflammation.	19207328
Deglutition Disorders, Inflammation, Pain Distress Question	Altered Intercellular Communication	Symptoms of dysphagia, recurrent inflammation of the respiratory tract, and pain subsided in all patients.	19207550
Inflammation, Gastro-esophageal reflux disease with esophagitis	Altered Intercellular Communication	We studied this hypothesis by comparing markers of inflammation and cellular proliferation in EE and reflux esophagitis.	19207551
Chronic infectious disease, Fibrosis Assessment, Inflammation, Pulmonary Fibrosis	Altered Intercellular Communication	Of 2136 patients with AS, 63 (2.9%) developed apical lung fibrosis, of which chronic infections were the cause in 41 and AS inflammation predisposed the fibrosis in 22 patients.	19208564
Communicable Diseases, Fibrosis Assessment, Lesion of lung	Altered Intercellular Communication	Lung cavity lesion appeared to be a crucial differentiator (p = 0.009, odds ratio 7.4, 95% CI 1.5-36.0) between TB infection and AS inflammation-induced apical fibrosis.	19208564
Communicable Diseases, Inflammation	Altered Intercellular Communication	They recognize infectious and endogenous threats, so-called danger signals, that evoke inflammation and assist adaptive immune reactions.	19208601
Refractory anemias, Inflammation, Arthritis	Altered Intercellular Communication	Elevated levels of IL-17A have been detected in the inflamed synovium of RA patients, and murine arthritis models deficient in IL17A have shown reduced inflammation.	19208686
Gastrointestinal inflammation, Colitis	Altered Intercellular Communication	Intestinal inflammation is generally associated with increased mucosal permeability, but little is known about barrier function in microscopic colitis.	19209166
Malignant tumor of colon	Altered Intercellular Communication	Comparison of tumour-based (Petersen Index) and inflammation-based (Glasgow Prognostic Score) scoring systems in patients undergoing curative resection for colon cancer.	19209171
Inflammation, cervical cancer	Altered Intercellular Communication	The differences in antibody response between patients with inflammation and patients with cervical cancer were significant.	19210223
Inflammation, Psoriasis, Cardiovascular Diseases	Altered Intercellular Communication	Systemic inflammation may increase the risk for cardiovascular diseases in patients with psoriasis, but data on this risk in patients with early psoriasis are scarce.	19210501
Gastroesophageal reflux disease, Chronic inflammation	Altered Intercellular Communication	Gastroesophageal reflux disease (GERD) is associated with chronic inflammation and histomorphological alterations of the gastroesophageal junction and esophageal mucosa.	19212204
Gastroesophageal reflux disease, Inflammation, Basal cell hyperplasia	Altered Intercellular Communication	Histology revealed higher chronic inflammation (P=0.04) and significant alterations of the intercellular spaces, basal cell hyperplasia, and length of papilla (P<0.05) in patients with GERD.	19212204
Gastroesophageal reflux disease, Inflammation	Altered Intercellular Communication	GERD, a chemically induced inflammation, does not affect mucosal SLPI expression in gastroesophageal mucosa.	19212204
Inflammation, Chronic heart failure	Altered Intercellular Communication	Adrenomedullin and endothelin-1 are related to inflammation in chronic heart failure.	19212702
Inflammation, Heart failure	Altered Intercellular Communication	Vasoregulation and inflammation may be connected in heart failure patients independently of the disease severity.	19212702
Inflammation, Appendicitis, CTCAE, Chronic pain	Altered Intercellular Communication	The term chronic appendicitis has been used to describe any type of chronic pain that originates in the appendix, with or without inflammation.	19213216
Inflammation, Infection, Paratestis, Traumatic injury, Reactive	Altered Intercellular Communication	These comprise approximately 6 percent of paratesticular lesions, and are accepted as reactive lesions secondary to trauma, hydrocoele, infections or inflammation.	19213380
Inflammation, Typhlitis, Enterocolitis, Neutropenic, Immunocompromised Host, leukemia, Necrotizing enterocolitis in fetus OR newborn	Altered Intercellular Communication	Neutropenic enterocolitis (NEC) also known as typhlitis is an acute, life-threatening inflammation of the small and large bowel often seen in patients with leukaemia undergoing cytotoxic chemotherapy: occasionally this syndrome could present in other immunocompromised patients.	19213496
Retinal Neovascularization, Inflammation, Retinal Vasculitis, Retinal ischemia	Altered Intercellular Communication	Ophthalmological examination and fluorescein angiography was performed and showed retinal neovascularization in the left eye, secondary to retinal ischemia and retinal sequelae vasculitis without inflammation or complications in the right eye.	19213518
Inflammation, Keratosis, Squamous cell carcinoma of skin	Altered Intercellular Communication	Cutaneous squamous cell carcinoma and inflammation of actinic keratoses associated with sorafenib.	19213663
Inflammation, Squamous cell carcinoma of skin	Altered Intercellular Communication	Cutaneous squamous cell carcinoma (SCC) and inflammation of actinic keratosis (AK) were reported in 2 patients treated with sorafenib (Lacouture et al), but the scope of this observation has not been evaluated.	19213663
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	Gelsolin expression is necessary for the development of modelled pulmonary inflammation and fibrosis.	19213772
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	To decipher the possible role of gelsolin in pulmonary inflammation and fibrosis, immunocytochemistry on tissue microarrays of human patient samples was performed followed by computerised image analysis.	19213772
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	The results were validated in the bleomycin-induced animal model of pulmonary inflammation and fibrosis using genetically-modified mice lacking gelsolin expression.	19213772
Idiopathic Interstitial Pneumonias, Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	Increased gelsolin expression was detected in lung samples of patients with idiopathic interstitial pneumonia as well as in modelled pulmonary inflammation and fibrosis.	19213772
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	Genetic ablation of gelsolin protected mice from the development of modelled pulmonary inflammation and fibrosis attributed to attenuated epithelial apoptosis.	19213772
Fibrosis Assessment, Lung Injury, Pneumonitis	Altered Intercellular Communication	Gelsolin expression is necessary for the development of modelled pulmonary inflammation and fibrosis, while the caspase-3-mediated gelsolin fragmentation was shown to be an apoptotic effector mechanism in disease pathogenesis and a marker of lung injury.	19213772
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Anti-inflammatory drugs are lacking in chronic obstructive pulmonary disease (COPD) and inhibitors of the phosphodiesterase type-4 (PDE4) enzyme have been suggested to be an interesting class of drugs to treat inflammation in COPD.	19213793
Inflammation, Endocarditis	Altered Intercellular Communication	In the worst case, there is a systemic inflammation with lead vegetations and endocarditis.	19214418
Inflammation	Altered Intercellular Communication	At the time of accommodation there were local and systemic signs of inflammation and bacterial vegetations at the ventricular lead, and explantation of the pacemaker and rehabilitation of the pocket was indicated.	19214418
Inflammation, Gastrointestinal mucositis, Peri-Implantitis	Altered Intercellular Communication	Clinical and radiologic assessments were the basis for the classification into 3 categories: (1) no inflammation, (2) mucositis, and (3) peri-implantitis.	19216280
Inflammation, Gastrointestinal mucositis	Altered Intercellular Communication	For mucositis, rates of 16.3% to 24.1% were seen, and 30% to 70.9% of sites showed no inflammation.	19216280
Inflammation, Cardiac Arrest, Blood Coagulation Disorders, Comatose, Brain Injuries, Cardiovascular Physiological Phenomena	Altered Intercellular Communication	Comatose survivors of out-of-hospital cardiac arrest (OHCA) have high in-hospital mortality due to a complex pathophysiology that includes cardiovascular dysfunction, inflammation, coagulopathy, brain injury and persistence of the precipitating pathology.	19217200
Allergic asthma, Pneumonitis	Altered Intercellular Communication	Additionally, treatment with a synthetic PPARG ligand can reduce lung inflammation and IFN-gamma, IL-4, and IL-2 production in experimental allergic asthma.	19217272
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Our prospective findings support the suggested role for inflammation in increasing future depressive symptom severity and extend this linkage for the first time to HF.	19217936
Inflammation, Complications of Diabetes Mellitus, Obesity	Altered Intercellular Communication	Obesity is associated with low-grade inflammation and leukocyte infiltration in white adipose tissue (WAT) and is linked to diabetic complications.	19218346
Inflammation, Obesity	Altered Intercellular Communication	Therefore, AOC3-KO mice present a unique model of mild obesity, characterized by increased WAT devoid of low-grade inflammation.	19218346
Airway structure, Chronic Obstructive Airway Disease, Asthma	Altered Intercellular Communication	Eosinophilic airway inflammation in chronic obstructive pulmonary disease and asthma.	19218650
Airway structure, ARCN1 gene, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Eosinophilic airway inflammation is regarded as a typical feature of asthma, while in chronic obstructive pulmonary disease (COPD) neutrophils seem predominant inflammatory airway cells.	19218650
Airway structure, ARCN1 gene, Asthma	Altered Intercellular Communication	The aim of the present study was to compare the cellular components of airway inflammation in patients with newly diagnosed mild or moderate COPD and asthma.	19218650
Airway structure, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Comparison of cellular and biochemical markers of airway inflammation in patients with mild-to-moderate asthma and chronic obstructive pulmonary disease: an induced sputum and bronchoalveolar lavage fluid study.	19218651
Airway structure, ARCN1 gene, Asthma	Altered Intercellular Communication	The aim of the present study was to compare the cellular and biochemical features of airway inflammation in patients with asthma and COPD.	19218651
Airway structure, ARCN1 gene, Asthma	Altered Intercellular Communication	The evaluation of BALF reveals more differences in the cellular and biochemical features of airways inflammation in patients with asthma and COPD than that of IS.	19218651
Inflammation, Granulomatosis with polyangiitis, Glomerulonephritis	Altered Intercellular Communication	Wegener's granulomatosis is a systemic disease characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tract and necrotizing crescentic glomerulonephritis.	19218710
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	25-Hydroxyvitamin D deficiency and inflammation and their association with hemoglobin levels in chronic kidney disease.	19218791
Inflammation, Anemia	Altered Intercellular Communication	There is limited information about the association of anemia with 25-hydroxyvitamin D [25(OH)D] deficiency and inflammation in the setting of decreased kidney function in the general population.	19218791
Inflammation, Anemia	Altered Intercellular Communication	We examined the association that anemia has with 25(OH)D deficiency and inflammation among 16,301 participants in the Third National Health and Nutrition Examination Survey (NHANES III).	19218791
Inflammation, Demographics Domain, Diabetes Mellitus	Altered Intercellular Communication	The status of inflammation may affect the collateral development in patients with diabetes mellitus (DM).	19219401
Refractory anemias, Inflammation, Rheumatoid Arthritis, Periarticular osteoporosis	Altered Intercellular Communication	Joint inflammation in rheumatoid arthritis (RA) induces local periarticular osteoporosis.	19219607
Refractory anemias, UGCG gene, Functional disorder	Altered Intercellular Communication	Both types of bone mass depletion can issue from cytokine-induced (TNF-alpha, IL-1, IL-6) osteoclasts' activation, osteoprotegerin and its ligand's (RANKL) function disorders, patients' immobilisation and glucocorticosteroid (GCS) intake, as well as from hormonal alterations in postmenopausal women, predominate among RA individuals.	19219607
Airway structure	Altered Intercellular Communication	Asthmatic ASM may modulate airway inflammation locally by increasing CD40 and OX40L expression in response to cytokines.	19220210
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	Increased metal allergy in patients with failed metal-on-metal hip arthroplasty and peri-implant T-lymphocytic inflammation.	19220218
Hypersensitivity	Altered Intercellular Communication	In 16 patients with revised metal-on-metal arthroplasty and peri-implant lymphocytic inflammation, we verified the role of metal hypersensitivity by patch testing (PT) and lymphocyte transformation test (LTT).	19220218
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	The lymphocyte dominated peri-implant inflammation may well reflect an allergic hyper-reactivity in these patients, given the high rate of concomitantly found metal allergy.	19220218
Fibrosis Assessment, Hepatitis, Necrosis	Altered Intercellular Communication	Liver histology still represents the gold standard for the assessment of liver inflammation, necrosis, and fibrosis.	19220661
Inflammation, Cerebral Atherosclerosis, Pathology	Altered Intercellular Communication	T2 and precontrast and postcontrast T1 fluid-attenuated inversion recovery images at 3 tesla may be able to differentiate enhancement patterns of intracranial atherosclerotic plaques (eccentric), inflammation (concentric), and other wall pathologies.	19221296
Inflammatory abnormality of the eye	Altered Intercellular Communication	The offending drug should be discontinued once the diagnosis is made, in order to prevent involvement of the contralateral eye and recurrent or chronic ocular inflammation.	19221448
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	Low grade inflammation is of pathogenic importance in the development of cardiovascular disease (CVD) and type 2 diabetes.	19223085
Inflammation, Constriction procedure	Altered Intercellular Communication	Histopathologic examination of the excised epicardium revealed neovascularization, minimal inflammation and thickened hyaline connective tissue and was diagnosed as constrictive percarditis and epicarditis.	19223307
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Coronary Arteriosclerosis	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) has been identified as a risk factor for ischaemic heart disease, independent of smoking history, and inflammation is thought to play a role.	19223680
ARCN1 gene, Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	We sought to ascertain whether occult myocardial infarction (MI) was present in the COPD population, and to assess its relationship with inflammation and natriuretic peptides.	19223680
Pharyngitis, Anxiety, CTCAE 3.0, Inflammatory disorder of cartilage, Dyspnea, Anti-Arrhythmia Agents, dendritic spine neck	Altered Intercellular Communication	These data led to identification of a persistent respiratory infection-related clinical syndrome, including persistent throat infection, neck spinal lesion, rib cartilage inflammation, symptoms of cardiac depression and dyspnea with or without anxiety.	19224156
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	The links among smoking, inflammation, and cardiovascular disease (CVD) are well established.	19225057
MS gene	Altered Intercellular Communication	The particularly high levels of CXCL10 and CXCL8 expressed by brain endothelium may contribute to the predominant TH1-type inflammatory response observed in chronic inflammatory conditions such as multiple sclerosis.	19225413
Inflammation, Prehypertension	Altered Intercellular Communication	Carotid artery stiffness, high-density lipoprotein cholesterol and inflammation in men with pre-hypertension.	19225528
Inflammation, Hyperamylasemia, Duodenal Ulcer	Altered Intercellular Communication	We speculated that the primary cause of hyperamylasemia was accumulation of amylase in the parotid glands and the CT findings showed the inflammation of the pancreas itself or extrapancreatic exdates resulting from duodenal ulcer.	19227173
Inflammation, Ascites, Abdominal Pain	Altered Intercellular Communication	A 55-year-old man admitted on April 1, 2008, for sudden abdominal pain onset whose laboratory data demonstrated apparent inflammation and whose computed tomography (CT) results showed free air and ascites underwent emergency surgery.	19227226
Inflammation	Altered Intercellular Communication	Signs of inflammation, its severity and extent were evaluated.	19227309
Inflammation, Gastritis	Altered Intercellular Communication	Significant correlation was revealed for the first time between inflammation of gastric mucosa, type of gastritis, endoscopic picture in the NBI regime, and results of histologic studies.	19227309
Intestinal metaplasia	Altered Intercellular Communication	Inflammation foci and sites of intestinal metaplasia were found to produce characteristic images in which they had different shades of lilac and deep blue respectively.	19227309
Inflammation, Metaplasia	Altered Intercellular Communication	Distribution of the stained foci corresponded to that of inflammation and/or metaplasia.	19227309
Inflammation, Bronchial Hyperreactivity, Overweight, Obesity	Altered Intercellular Communication	Despite overweight and obesity are being related to a low-grade of basal systemic inflammation, there was no association with a higher basal bronchial hyperresponsiveness in these individuals.	19227648
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	In AS, reduced IL-10 production in response to stimulation with autologous Bacteroides cultures may represent a mechanism by which intestinal inflammation develops and persists, a situation analogous to inflammatory bowel disease.	19228651
Inflammation, Hypertriglyceridemia, Obesity	Altered Intercellular Communication	Patients in the highest fetuin A tertile had 3.2- and 4.4-fold higher incidence of truncal obesity (P=0.038) and hyper-triglyceridemia (P=0.015) independent of nutritional status and inflammation.	19228823
Inflammation, Malnutrition, Dyslipidemias, Obesity	Altered Intercellular Communication	Fetuin A is positively associated with truncal obesity and dyslipidemia, which are independent of malnutrition and inflammation.	19228823
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Relation of abdominal fat depots to systemic markers of inflammation in type 2 diabetes.	19228869
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Our findings suggest that adipose tissue distribution remains an important determinant of systemic inflammation in type 2 diabetes.	19228869
Inflammation, Hypoadiponectinemia, Coronary Arteriosclerosis, Atherosclerosis	Altered Intercellular Communication	In the present study we demonstrated that elevated PAT volumes are associated with coronary atherosclerosis, hypoadiponectinemia, and inflammation and represent the strongest risk factor for the presence of atherosclerosis and may be important for risk stratification and monitoring.	19229071
Inflammation, Obesity	Altered Intercellular Communication	Markers of inflammation and hemodynamic measurements in obesity: Copenhagen City Heart Study.	19229196
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Low-grade chronic inflammation has been proposed to play a major role in the pathogenesis of hypertension.	19229196
Inflammation, Hypertension, CTCAE, Obesity	Altered Intercellular Communication	Low-grade chronic inflammation is also closely associated with obesity, an established causative factor in the development of hypertension.	19229196
ARCN1 gene, Inflammation	Altered Intercellular Communication	Our findings are consistent with systemic inflammation in COPD associated with an increased influx of cytotoxic and Th1 cells into the airway.	19229703
Inflammation, Dacryocystitis	Altered Intercellular Communication	Histopathologically, the presence of chronic inflammation was noted more frequently (p < 0.001, Kruskal-Wallis test), with a shorter time interval between surgery and last dacryocystitis.	19229737
Inflammation, Dyslipidemias, Atherosclerosis	Altered Intercellular Communication	Uremic dyslipidemia and inflammation take part in the etiology of atherosclerosis.	19229822
Sarcoidosis, Primary malignant neoplasm	Altered Intercellular Communication	Sarcoidosis is a chronic inflammatory condition that may increase the risk of cancer, but limited information is available on occurrence of cancer in these patients.	19230028
Oral Ulcer, Inflammation, Hemorrhage	Altered Intercellular Communication	These diseases affect the digestive system and cause the inflammation of intestinal tissue, form sores and bleed easily.	19230040
MPV17 gene, Interstitial inflammation, Tubular atrophy	Altered Intercellular Communication	In the glomeruli the extent of C5b-9 deposition had significant positive correlations with the degree of focal glomerulosclerosis (p=0.005), tubular atrophy (p=0.003), interstitial inflammation (p=0.005) and tubular expression of alpha3beta1 (p=0.0001).	19230171
Sepsis, Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	The blood taken from patients with sepsis showed the significant increase in the levels of dead leukocytes as compared with both the physiological normal values and the values obtained in patients without signs of systemic inflammation, which significantly correlates with the severity of organ dysfunction.	19230181
Necrosis of retina, Orbital Pseudotumor	Altered Intercellular Communication	Painful orbital inflammation and scleritis-like clinical appearance can be the initial manifestation of acute retinal necrosis.	19230360
Inflammation, Bulbar urethra, Congenital MeSH qualifier, Stenosis	Altered Intercellular Communication	This outcome, in conjunction with the bimodal age distribution at presentation, would suggest a different aetiology in older children, and we would urge caution in classifying strictures in ambulant children as genuinely congenital, as this population may represent the long-term manifestation of unrecorded bulbar urethral trauma or asymptomatic inflammation.	19230775
Inflammation, Allergic	Altered Intercellular Communication	Systemic inflammation might play a role in the development of allergic disease.	19230960
Granulomatous inflammation	Altered Intercellular Communication	Thirteen patients (61.9%) showed granulomatous inflammation on histopathologic examination, and 10 of 15 patients (66.7%) were positive on a TB polymerase chain reaction assay.	19231490
Inflammation, Thrombophilia, Ulcer, Sample Size Calculation, Avascular Necrosis, CTCAE	Altered Intercellular Communication	The diffuse SSc phenotype with avascular areas on capillaroscopy, thrombophilia, and systemic inflammation as defined by interleukin 6 plasma levels, represented the major risk factors for ulcer development.	19231640
Inflammation, Cardiac complication, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation contributes to cardiovascular complications in type 2 diabetes, which are often characterized by microvascular alterations.	19232095
Proteinuria, Inflammation	Altered Intercellular Communication	MRP8/14 was positively associated with inflammation (r = 0.57), proteinuria (r = 0.40) and retinal arterial caliber (r = 0.48).	19232095
Diabetic Nephropathy, Inflammation	Altered Intercellular Communication	MRP8/14--a marker for transendothelial migration--describes not only the state of inflammation in diabetic nephropathy, but additionally the degree of microvascular alterations in the glomerular and retinal bed.	19232095
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histopathologic examination of EGD biopsies of the flat lesion showed brown crystalline materials deposited in the lamina propria of gastric mucosa, which was accompanied with fibrosis, chronic inflammation, and foreign body reaction.	19232839
Inflammation, selenium	Altered Intercellular Communication	In all cases, the superficial cranial arteries displayed mural inflammation in post-contrast T1-weighted spin-echo (SE) images.	19233887
Cataract, Inflammation	Altered Intercellular Communication	One injection of DuoCat had a therapeutic response and ocular tolerance that were equivalent to conventional eye drops in controlling inflammation after cataract surgery.	19234342
Inflammation, Sarcopenia	Altered Intercellular Communication	Increased inflammation with aging has been linked to sarcopenia.	19234585
Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Markers of inflammation were related to plaque size alone, implying inflammation to be predominantly associated with the amount of atherosclerosis.	19234732
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Heightened thrombogenicity and biomarker evidence of inflammation have been independently associated with ischemic risk in patients with coronary artery disease.	19235051
Inflammation, Osteolysis	Altered Intercellular Communication	As scavenger receptor MARCO apparently participates in handling of wear particles, which due to their nondegradable, irritating nature initiate/perpetuate foreign body inflammation, and peri-implant osteolysis.	19235220
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Prospective studies have identified chronic inflammation as a risk factor for Type 2 diabetes.	19236617
Inflammation, Nucleolar Fibrillar Material, Atherosclerosis	Altered Intercellular Communication	Valvular atherosclerosis is defined as extra- and intracellular lipid deposition, thickening of the fibrosa layer, decreased thickness of the spongiosa, and chronic inflammation.	19237022
Inflammation, Chronic heart failure, Hyperuricemia, Congestive heart failure	Altered Intercellular Communication	Hyperuricemia is a prevalent condition in chronic heart failure (CHF), describing increased oxidative stress and inflammation.	19237097
Inflammation, Skin lesion, Ulcer, Uveitis, Behcet Syndrome	Altered Intercellular Communication	Behcet's disease (BD) has been recognized as multi-systemic chronic vasculitic disorder of recurrent inflammation, characterized by the involvement of multiple organs and resulting in orogenital ulcers, uveitis, and skin lesions.	19237836
Lymphocytic hypopituitarism	Altered Intercellular Communication	Lymphocytic hypophysitis is an unusual inflammatory condition of the pituitary gland, classically seen in females during the peripartum periods.	19237858
Inflammation, Obesity	Altered Intercellular Communication	It has been recognized that obese individuals are intrinsically in a state of chronic inflammation, as indicated by positive correlations between serum levels of C-reactive protein (CRP) and various anthropometric measures of obesity.	19238141
Communicable Diseases, Inflammation	Altered Intercellular Communication	Evidence of systemic inflammation (> 1 criteria) and suspicion for infection.	19238354
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Dimethylarginines and inflammation markers in patients with chronic kidney disease undergoing dialysis.	19238516
Inflammation	Altered Intercellular Communication	Chronic inflammation was identified in 25 biopsies (27%).	19239457
Inflammation, Memory impairment	Altered Intercellular Communication	Chronic CHF5074 treatment reduced brain beta-amyloid burden, associated microglia inflammation and attenuated spatial memory deficit in hAPP mice.	19239474
Ileus, CTCAE, Proctitis, Small bowel obstruction	Altered Intercellular Communication	Regression modeling showed the following to be significantly associated with severe CDAD (p< or =0.05): age >70 years (odds ratio [OR] 3.35), maximum leukocyte count >20,000 cells/mL (OR 2.77), minimum albumin level <2.5 g/dL (OR 3.44), maximum creatinine level >2 mg/dL (OR 2.47), small bowel obstruction or ileus (OR 3.06), and computed tomography scan showing colorectal inflammation (OR 13.54).	19239754
Inflammation, melanoma	Altered Intercellular Communication	Evidence of systemic Th2-driven chronic inflammation in patients with metastatic melanoma.	19240164
melanoma, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Patients with metastatic melanoma exist in a state of Th2-mediated "chronic inflammation" as a result of at least VEGF overproduction by malignant tumors.	19240164
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	A total of 49.2% of patients in this study had significant inflammation (grade >or=2) and 36.4% had significant fibrosis (stage >or=2).	19241166
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The frequency of serious inflammation and fibrosis was similar in patients with different ALT levels.	19241166
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The level of serum HBV DNA was not significantly associated with the extent of inflammation and fibrosis.	19241166
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Advanced age was a significant independent predictor of histological damage and the presence of more significant inflammation and fibrosis.	19241166
Inflammation, Uveitis	Altered Intercellular Communication	We conclude that ultra wide field fluorescein angiography is important to detect inflammation early and follow treatment in patients with intermediate uveitis.	19241289
Intra-abdominal	Altered Intercellular Communication	Severe intra-abdominal inflammation was present in three cases of group 2 where we obtained false positive results which may stimulate the pancreatic exocrine secretion.	19241920
Inflammation, Sarcoidosis	Altered Intercellular Communication	In patients with suspected sarcoidosis requiring pathologic confirmation of the presence of noncaseating granulomatous inflammation and the exclusion of alternative disorders, bronchoscopic transbronchial lung biopsy and more recently transbronchial needle aspiration of mediastinal lymph nodes have been the standard biopsy procedures in most cases.	19242299
Inflammation, Giant Cell Arteritis, Hypermetabolism	Altered Intercellular Communication	The combination of laboratory and imaging findings, including the characteristic inflammatory changes involving the large vessel walls as seen on CT, as well as the vessel wall hypermetabolism on FDG PET indicating active inflammation, resulted in the diagnosis of large vessel giant cell arteritis.	19242771
Gastroesophageal reflux disease, Cardia of stomach, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Chronic mucosal inflammation of the gastric cardia in gastroesophageal reflux disease is not regulated by FOXP3-expressing T cells.	19242793
Gastroesophageal reflux disease, Inflammation, Helicobacter pylori, Cardia of stomach	Altered Intercellular Communication	Chronic inflammation at the cardia occurs in gastroesophageal reflux disease (GERD), as well as in the presence of Helicobacter pylori.	19242793
Inflammation	Altered Intercellular Communication	GERD presented with chronic inflammation and reduced FOXP3-mRNA in the cardiac mucosa (-84%), whereas H. pylori-positive patients revealed a 25.1-fold increase of FOXP3 gene expression.	19242793
Gastroesophageal reflux disease, Inflammation, Cardia of stomach	Altered Intercellular Communication	Chronic inflammation at the cardia associated with either GERD or H. pylori differs concerning the presence of FOXP3-expressing T cells.	19242793
HD Term Type, Inflammation, Overweight	Altered Intercellular Communication	According to a multiple linear regression analysis, with PA as the dependent variable, age (beta = 0.274, P = .008), creatinine (beta = 0.355, P = .001), and log sOB-R/leptin ratio (beta = -0.465, P = .008) were significant independent predictors of PA. HD patients with elevated BMI demonstrate better nutritional status compared to normal BMI or overweight patients, whereas the severity of inflammation is not related to BMI in HD patients.	19243974
Inflammation, Cachexia	Altered Intercellular Communication	The genetic predisposition of the host to local or systemic inflammation may contribute to the effect of cancer cachexia.	19244371
Prostate	Altered Intercellular Communication	Increased p53 immunoreactivity in proliferative inflammatory atrophy of prostate is related to focal acute inflammation.	19245591
Muscle, Smooth, Vascular, Tissue Factor	Altered Intercellular Communication	Adenoviral overexpression of Egr-1 in human vascular smooth muscle and endothelial cells was found to up-regulate the expression of TF and inflammation-related genes.	19245972
Inflammation, Foreign-Body Reaction	Altered Intercellular Communication	Understanding the cellular response to a biologic graft used in rotator cuff applications is important because foreign-body reactions and inflammation complications have historically been seen with xenograft-derived grafts.	19245998
Inflammation	Altered Intercellular Communication	The shortening observed over time may be attributable to inflammation induced by the TCP.	19246039
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	The pathogenesis of aortic valve stenosis may involve inflammation and we have previously demonstrated Chlamydophila pneumoniae (C. pneumoniae) DNA in stenotic aortic heart valves.	19246110
Eosinophilic inflammation	Altered Intercellular Communication	Eosinophil inflammation seems to develop through a different pathway in EP compared to other ILDs.	19246876
Pain Distress Question, Inflammation, Temporomandibular Joint, Neoplasms, Temporomandibular Joint Disorders, Trismus, Traumatic injury	Altered Intercellular Communication	Diseases causing trismus or pain of the temporomandibular joint (TMJ) include temporomandibular joint disorders (TMJD), trauma, tumors and an inflammation.	19246964
Inflammation	Altered Intercellular Communication	When we treat TMJD, we must keep in mind the possibility of the inapparent presence of some unseen inflammation, especially an abscess formation in the masticator space.	19246964
Intraocular inflammation, Mildly reduced visual acuity, Hemorrhage, Hyperemia	Altered Intercellular Communication	After PNT, no patients had visual acuity reduction or intraocular inflammation; three eyes had subconjunctival hemorrhage and five eyes a hyperemia that regressed within 1 week.	19247684
Airway structure, Fibrosis Assessment	Altered Intercellular Communication	The most characteristic feature of airway inflammation in cystic fibrosis (CF) is the persistent infiltration of massive numbers of neutrophils.	19247707
Inflammation	Altered Intercellular Communication	Although inflammation is primarily a protective response to injury, it has the potential to cause considerable harm when it is excessive.	19247707
Inflammation	Altered Intercellular Communication	Recent recognition of the prominent role of inflammation has prompted the investigation of treatments designed to control inflammation in the CF lung.	19247707
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Biomarkers of inflammation and development of rheumatoid arthritis in women from two prospective cohort studies.	19248103
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To examine the association of biomarkers of inflammation with preclinical rheumatoid arthritis (RA).	19248103
Arthritis	Altered Intercellular Communication	These observations suggest that locally produced IL-33 may contribute to the pathogenesis of joint inflammation and destruction.	19248109
Inflammation, Cerebrovascular accident, Coronary heart disease	Altered Intercellular Communication	Fruits and vegetables, foods rich in flavonoids and antioxidants, have been associated with lower risk of stroke, coronary heart disease, and markers of inflammation and oxidative stress in adults.	19248856
Inflammation, Coronary heart disease	Altered Intercellular Communication	Markers of inflammation and oxidative stress are predictors of coronary heart disease risk; however, it is unknown whether these markers are related to dietary flavonoid and antioxidant intake in youth.	19248856
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Recent studies have indicated a close relationship between hypertension and inflammation.	19249142
ARCN1 gene, Inflammation, Respiratory physiology	Altered Intercellular Communication	Recent studies show that COPD patients exhibit low-grade systemic inflammation, and that plasma fibrinogen and high neutrophil counts are related to faster declines in lung function.	19249197
Interstitial inflammation	Altered Intercellular Communication	Diffuse PTC-itis (P = .029, RR [95% confidence interval] = 3.349 [1.131-9.919]) and total interstitial inflammation score (P = .015, RR [95% confidence interval] = 9.662 [1.784-52.329]) were observed to show a negative impact on graft survival.	19249499
TG gene, Inflammation, Percutaneous transhepatic cholangiography	Altered Intercellular Communication	The survival of kidney grafts with TG was significantly affected by the magnitude of inflammation in the interstitium and PTC, but not by C4d positivity in PTC and glomeruli.	19249499
Inflammation, Endometriosis	Altered Intercellular Communication	Endometriosis (33%) and inflammation (76%) were the most common pathologic findings in adults and children, respectively.	19249733
Inflammation, Congenital arteriovenous malformation	Altered Intercellular Communication	Recent evidence on the role of inflammation in the pathogenesis of AVMs and the pathophysiology of AVM rupture is presented.	19249934
Inflammation, Doxorubicin/Methotrexate/Vinblastine	Altered Intercellular Communication	Inflammatory markers have been demonstrated in brain AVM tissue, and the association between inflammation and AVM hemorrhage has been established.	19249934
Inflammation	Altered Intercellular Communication	Besides, chronic inflammation plays a key role in PCa.	19250219
Inflammation, Hepatocarcinogenesis	Altered Intercellular Communication	Hepatocarcinogenesis is a multistep process characterized by hepatocyte inflammation, regeneration, and proliferation.	19250220
Unknown (origin) (qualifier value), Inflammation, Drug-induced, Sweet Syndrome	Altered Intercellular Communication	Sweet syndrome can be subdivided into the classical form, which is usually idiopathic and is associated with some kind of inflammation, the paraneoplastic form and the drug-induced one.	19250247
Inflammation, Arteritis	Altered Intercellular Communication	Biopsy, however, revealed lymphocytic inflammation with occlusion of the lumen of a small artery at the dermal-subcutaneous junction, characteristic of macular arteritis.	19250419
Idiopathic aortitis	Altered Intercellular Communication	Idiopathic aortitis is a rare condition characterized by giant cell or lymphoplasmacytic inflammation of the aorta.	19250534
Inflammation	Altered Intercellular Communication	Elevated acute-phase reactants as a marker of systemic inflammation may be present in some patients.	19250534
Inflammation	Altered Intercellular Communication	Moreover, P-glycoprotein transports various endogenous substrates such as cytokines and chemokines involved in inflammation, and may thereby affect the risk of malignity.	19250544
Inflammation, Carcinogenesis	Altered Intercellular Communication	Epidemiological and experimental data demonstrate, that inflammation contributes significantly to pancreatic carcinogenesis.	19251436
Airway structure	Altered Intercellular Communication	Shed syndecan-1 restricts neutrophil elastase from alpha1-antitrypsin in neutrophilic airway inflammation.	19251947
Inflammation	Altered Intercellular Communication	CDX2 expression correlated positively with the degree of IM (p<0.01) and the degree of H pylori induced inflammation (p<0.05).	19251954
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Markers of airway inflammation and oxidative stress have been mainly investigated in moderate/severe chronic obstructive pulmonary disease (COPD) or during its exacerbation.	19252398
ARCN1 gene, Inflammation	Altered Intercellular Communication	The results point to an advantage of induced sputum over EBC for assessing the degree of airway oxidative stress and inflammation in smokers with a potential risk for COPD development.	19252398
Inflammation, Vascular Diseases	Altered Intercellular Communication	The MITICO study was designed to assess the prognostic value of markers of inflammation in relation to the risk of recurrence of vascular disease.	19252763
Inflammation	Altered Intercellular Communication	The expression of disintegrin and metalloprotease ADAM-9, ADAM-15, and ADAM-17 has been associated with cell-cell, cell-platelet, and cell-matrix interactions and inflammation.	19253070
Chronic inflammation, Structure of maxillary molar tooth, Floor - story of building	Altered Intercellular Communication	Sinus floor elevation from a maxillary molar tooth extraction socket in a patient with chronic inflammation.	19254137
Floor - story of building, Chronic inflammation, Structure of maxillary molar tooth, Periodontal Route of Administration	Altered Intercellular Communication	This article documents a sinus floor elevation technique through an extraction socket in a 65-year-old white male with chronic inflammation to increase the bone mass after the extraction of a periodontally involved maxillary molar tooth.	19254137
Inflammation, Sinusitis	Altered Intercellular Communication	Computerized tomography revealed an increased thickness of the sinus membrane, which was attributed to possible chronic sinus inflammation and periodontal inflammation.	19254137
Inflammation, Elevation	Altered Intercellular Communication	After consultation with the Department of Otolaryngology, it was diagnosed as chronic inflammation without any contraindication for sinus elevation surgery or implant placement.	19254137
Gingivitis, Ankyloglossia, Dental caries	Altered Intercellular Communication	Intraoral examination revealed multiple carious lesions affecting almost the entire dentition, with severe gingival inflammation, mycrostomia, ankyloglossia and elimination of buccal and vestibular sulci.	19254527
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	These results suggest that PGE(2) inhibits the pathogenesis of SEB-induced eosinophilic inflammation primarily through the EP2-mediated pathway in patients with chronic rhinosinusitis with nasal polyposis.	19254809
hydrocortisone, Inflammation, Honeycomb appearance	Altered Intercellular Communication	Pathologically, CVD-UIP patients had fewer fibroblastic foci and smaller honeycombing (HC) spaces with higher germinal centers and total inflammation scores than IPF/UIP patients.	19255290
Dyspnea, Inflammation, Colonization, Respiratory Muscles	Altered Intercellular Communication	The following outcome variables were studied under stable conditions: dyspnea, nutritional status, complete lung function tests, respiratory and peripheral muscle strength, bronchial colonization, and systemic inflammation.	19255291
ARCN1 gene, Inflammation	Altered Intercellular Communication	More physically active COPD patients show better functional status in terms of Dlco, Pemax, 6MWD, Vo(2)peak, and systemic inflammation.	19255291
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	In rheumatoid arthritis (RA), chronically stimulated T lymphocytes sustain tissue-destructive joint inflammation.	19255426
Eosinophilic colitis	Altered Intercellular Communication	Eosinophilic colitis is an inflammatory condition characterized by infiltration of the colonic wall by eosinophils with submucosal oedema.	19256325
palladium, Inflammation, Malnutrition	Altered Intercellular Communication	A diet containing 0.6-0.8 g of protein/kg IBW/day is safe and, when combined with keto acids, is associated with an improved preservation of RRF in relatively new PD patients without significant malnutrition or inflammation.	19258386
Communicable Diseases, Inflammation	Altered Intercellular Communication	The optimal cutoffs of the inflammation tests for diagnosing infection were determined by constructing the receiver operating-characteristic curves.	19259644
Gastritis	Altered Intercellular Communication	NADPH oxidase, a major source of superoxide generation play a critical role in H. pylori related gastric inflammation.	19260521
Inflammation	Altered Intercellular Communication	Both testes were not felt distinctly and the overlying scrotal skin showed no signs of inflammation.	19260851
Inflammation, Peritonitis	Altered Intercellular Communication	Peritoneal fluid adipokine concentrations are characterized by individual SARs, depend on the presence of peritonitis, and correlate with underlying disease, BMI and systemic inflammation.	19260952
Inflammation	Altered Intercellular Communication	CT was useful for early diagnosis, confirmation of the extent of inflammation and follow-up.	19262050
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	The low hepcidin results in IBD patients may reflect a causal or perpetuator effect on intestinal inflammation.	19262400
Inflammation, Sarcopenia	Altered Intercellular Communication	Sarcopenia may be related to increases in reactive oxygen species formation and inflammation, both of which are associated with elevations in serum uric acid.	19262948
Inflammation, Thrombosis	Altered Intercellular Communication	These findings suggest that the CNP may result not only from mechanical compression by coils but also from inflammation induced by perpendicular thrombosis, and that the prognosis of the CNP may be influenced by dome re canalization.	19262981
Inflammation, Bacterial Infections	Altered Intercellular Communication	The discrimination between a bacterial infection and an aseptic inflammation with laboratory examinations like ESG, CRP or leukocytes is not possible.	19263315
Inflammation, Bacterial Infections	Altered Intercellular Communication	Furthermore, it is not useful for the discrimination between a bacterial infection and an aseptic inflammation of the spine.	19263315
Inflammation, Ischemic stroke	Altered Intercellular Communication	Inflammation and inflammatory markers play an important role in acute ischemic stroke (AIS).	19263524
Inflammation	Altered Intercellular Communication	However, the cellular source of these cytokines in psoriatic lesions are still poorly defined and their relative contribution in inducing skin inflammation has been discussed controversially.	19264456
Inflammation, Exacerbation	Altered Intercellular Communication	There is evidence that eosinophilic inflammation of the airway is associated with the risk of exacerbations.	19264686
Inflammation	Altered Intercellular Communication	The shared, unique, and/or complementary transcriptional and proteomic profiles may frame the context of the host response to P. gingivalis, contributing to the destructive nature of periodontal inflammation.	19264901
vascular inflammations, Atherosclerosis, Cerebrovascular accident	Altered Intercellular Communication	Lipid accumulation in arteries induces vascular inflammation and atherosclerosis, the major cause of heart attack and stroke in humans.	19265037
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	We hypothesized that biomarkers of inflammation or coagulation may be associated with the pathogenesis of ERILs and sought to investigate whether these biomarkers provide prognostic information on the risk of development of ERILs independently of clinical and imaging variables.	19265045
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	To support the data obtained from patient samples, the levels of IL-1beta and IL-18 mRNA and protein, pulmonary inflammation, and lung fibrosis were examined in mouse models of bleomycin-induced lung injury.	19265174
Inflammation	Altered Intercellular Communication	Novel disease-causing mechanisms and, therefore, drug targets, include epigenetics, inflammation, telomeres, mitochondrial function, oxidative stress and sirtuins.	19265603
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	In particular, PBMC from patients with Alzheimer disease (AD) have been suggested to carry apoptotic changes and alterations of neurotransmitter receptor expression, which may resemble those occurring in central nervous system neurons.	19266703
Inflammation, Prostate carcinoma, Structure of posterior cerebral artery	Altered Intercellular Communication	Inflammation is believed to play a role in prostate cancer (PCa) etiology, but it is unclear whether inflammatory markers C-reactive protein (CRP) and interleukin-6 (IL-6) associate with PCa risk in older men.	19267250
Inflammation, Thrombosis	Altered Intercellular Communication	Human platelets play a key role in hemostasis and thrombosis and have recently emerged as key regulators of inflammation.	19267493
Chronic Obstructive Airway Disease, Myositis	Altered Intercellular Communication	Increased serum inflammatory markers in the absence of clinical and skeletal muscle inflammation in patients with chronic obstructive pulmonary disease.	19270439
Leucocytic infiltrate, Myositis	Altered Intercellular Communication	Skeletal muscle inflammation was investigated microscopically using a panel of antibodies and standard staining for inflammatory cell infiltration.	19270439
ARCN1 gene, Inflammation	Altered Intercellular Communication	All COPD patients were clinically stable, with no sign of inflammation and normal CRP values.	19270439
Rhabdomyositis	Altered Intercellular Communication	No microscopic signs of skeletal muscle inflammation were observed.	19270439
ARCN1 gene, Inflammation	Altered Intercellular Communication	Our results identify hs-CRP as an early marker of inflammation that is significantly increased in the circulation even in mild COPD.	19270439
Rhabdomyositis	Altered Intercellular Communication	These changes were manifested in the absence of any clinical signs of disease exacerbation, evidence of skeletal muscle inflammation or hormonal changes.	19270439
Rhabdomyositis	Altered Intercellular Communication	These changes were manifested in the absence of any clinical signs of disease exacerbation, evidence of skeletal muscle inflammation or hormonal changes.	19270439
Acute Lung Injury, Inflammation, Respiratory Distress Syndrome, Adult, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	Angiopoietin-2 (Ang-2) is a potent regulator of vascular permeability and inflammation in acute lung injury and acute respiratory distress syndrome (ARDS).	19271210
Airway structure	Altered Intercellular Communication	Examinations included spirometry, levels of serum-specific IgE-antibodies, airway responsiveness to methacholine, exhaled nitric oxide (eNO) and evidence of airway inflammation in induced sputum.	19272083
Asthma, Eosinophilic inflammation	Altered Intercellular Communication	Remission group members with AHR had a significantly longer period of childhood asthma, a shorter period of remission and greater airway eosinophilic inflammation than those without AHR (P < 0.05).	19272083
Asthma, AHR wt Allele, Eosinophilic inflammation	Altered Intercellular Communication	One half of young adults with childhood asthma that remitted either during or before adolescence continued to have evidence of AHR and airway eosinophilic inflammation, and might be at risk of future relapse.	19272083
ARCN1 gene, Inflammation	Altered Intercellular Communication	IL6 and CRP haplotypes are associated with COPD risk and systemic inflammation: a case-control study.	19272152
ARCN1 gene, Inflammation	Altered Intercellular Communication	To date, it remains unclear whether and to what extent systemic inflammation is primary or secondary in the pathogenesis of COPD.	19272152
ARCN1 gene, Inflammation	Altered Intercellular Communication	However, COPD population was very heterogeneous: about 40% of patients had no evidence of systemic inflammation (CRP < 3 mg/uL or no inflammatory markers in their top quartile).	19272152
ARCN1 gene, Inflammation	Altered Intercellular Communication	Our findings suggest that common genetic variation in CRP and IL6 genes may contribute to heterogeneity of COPD population associated with systemic inflammation.	19272152
Inflammation, Generalized	Altered Intercellular Communication	Nail changes not only reflect generalised disease or inflammation but also localised peripheral conditions that affect the microcirculation.	19272612
Inflammation, Carotid Stenosis	Altered Intercellular Communication	Imaging of early inflammation in low-to-moderate carotid stenosis by 18-FDG-PET.	19273279
Inflammation, Carotid Stenosis	Altered Intercellular Communication	It is not clear if 18FDG-PET can be useful for detection of inflammation in low to moderate carotid stenosis.	19273279
Refractory anemias, Inflammation	Altered Intercellular Communication	In patients with RA, chronic inflammation and its suppression during anti-TNF therapy have limited influence on plasma leptin concentrations, while significantly decreasing circulating adiponectin levels.	19273452
Refractory anemias, Inflammation	Altered Intercellular Communication	In early RA, current inflammation seemed to affect the HPG axis, mainly at the gonadal rather than the hypothalamic-pituitary level.	19273455
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	The role of H. pylori as an initiator of inflammation is evident but the mechanism for development into gastric cancer has not yet been proven.	19273648
anatomical bulb, Fibrosis Assessment, Pterygium Of Conjunctiva And Cornea, Strabismus, Traumatic injury	Altered Intercellular Communication	Cases of bulbar conjunctival fibrosis from pterygium surgery, strabismus surgery, trauma, chemical exposure, and inflammatory conditions can be difficult to manage.	19273925
Orbital Pseudotumor, Paresthesia	Altered Intercellular Communication	Idiopathic sclerosing orbital inflammation: two cases presenting with paresthesia.	19273935
Orbital Pseudotumor, Paresthesia	Altered Intercellular Communication	The authors report 2 patients with idiopathic sclerosing inflammation of the orbit who presented with periorbital paresthesia in the trigeminal nerve distribution.	19273935
Scleritis, Malignant Neoplasms, Paresthesia	Altered Intercellular Communication	Although periorbital paresthesia is usually a sign of malignancy, these cases illustrate that it may also occur in patients with sclerosing orbital inflammation.	19273935
Acute inflammation of orbit	Altered Intercellular Communication	A 67-year-old man developed acute orbital inflammation after receiving cosmetic mesotherapy (Lipo-Dissolve) to the inferior orbital fat compartments.	19273937
Inflammation, Traumatic neuroma, Necrosis	Altered Intercellular Communication	Inflammation including fat necrosis and traumatic neuroma are all possible consequences of mesotherapy.	19273937
Histiocytosis haematophagic, Granulomatous inflammation, Caseous necrosis, Tuberculosis	Altered Intercellular Communication	A bone marrow smear showed extensive hemophagocytosis and the pathology disclosed granulomatous inflammation with caseous necrosis, suggestive of tuberculosis.	19274475
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	To determine the correlation of systemic interleukin-18 (IL-18) levels with disease activity and other markers of inflammation using a crosssectional pilot study in outpatients with IBD.	19274491
Inflammation	Altered Intercellular Communication	COMCLUSIONS: In CD IL-18 lacks significant correlation with the CDAI, as do serum acute phase protein and other cytokine markers of inflammation.	19274491
Pain Distress Question, Inflammation	Altered Intercellular Communication	A 59-year-old patient comes to a community pharmacy with unexplained, worsening bilateral foot pain and inflammation.	19275464
Inflammation	Altered Intercellular Communication	Polymorphonuclear neutrophil (PMN) apoptosis is one of the mechanisms responsible for the resolution of inflammation.	19276127
Inflammation, Diabetic peripheral neuropathy	Altered Intercellular Communication	We investigated the association between inflammation, microvascular reactivity, and the development of peripheral diabetic neuropathy.	19276232
Inflammation, Diabetic peripheral neuropathy, Endothelial dysfunction	Altered Intercellular Communication	Peripheral diabetic neuropathy is associated with increased biochemical markers of inflammation and endothelial dysfunction.	19276232
Inflammation, Endothelial dysfunction, Neuropathy	Altered Intercellular Communication	Painful neuropathy is associated with further increase in inflammation and markers of endothelial dysfunction and preservation of the nerve axon reflex.	19276232
Crohn Disease, Inflammation	Altered Intercellular Communication	Mural Crohn disease: correlation of dynamic contrast-enhanced MR imaging findings with angiogenesis and inflammation at histologic examination--pilot study.	19276323
Inflammation	Altered Intercellular Communication	Histopathologic sampling of the specimen was performed through the imaged tissue, and microvascular density (MVD) was determined, together with acute and chronic inflammation scores.	19276323
Inflammation	Altered Intercellular Communication	Neither acute nor chronic inflammation score correlated with any other parameter.	19276323
Chronicity, Crohn Disease, Inflammation	Altered Intercellular Communication	Certain MR imaging-derived mural hemodynamic parameters correlate with disease chronicity and angiogenesis in Crohn disease, but not with histologic and clinical markers of inflammation.	19276323
Inflammatory abnormality of the eye, Ocular surface disease	Altered Intercellular Communication	Out of 200 anti-CCP-/RF- patients, 32 (16%) had ocular surface disease and 2 (1%) had ocular inflammation.	19277223
Keratitis	Altered Intercellular Communication	Although 81% of patients had clinically quiescent disease, histopathology revealed that 74% had active corneal inflammation, a finding that was associated with the presence of clinical neovascularization (P = .01).	19277231
Herpes Simplex Infections, Inflammation, Failure (biologic function)	Altered Intercellular Communication	Histopathologic inflammation was a risk factor for allograft rejection (P = .02) but not failure (P = .98) or HSV recurrence (P = .45).	19277231
Inflammation	Altered Intercellular Communication	Histopathologic inflammation, neovascularization, and the presence of specific biomarkers are risk factors for corneal allograft morbidity.	19277231
Inflammation, Thrombosis	Altered Intercellular Communication	A close relationship between inflammation and thrombosis exists.	19277412
Inflammation	Altered Intercellular Communication	Bronchoscopy showed extensive space-occupying lesions with severe inflammation of the trachea.	19277935
Granulomatous inflammation, Necrotizing	Altered Intercellular Communication	Bronchial biopsy revealed necrotizing, granulomatous inflammation with dense infiltration of lymphatic cells.	19277935
Refractory Cytopenia of Childhood, Inflammation, Renal Cell Carcinoma Pathway, Obesity	Altered Intercellular Communication	Given that obesity, a state of chronic inflammation, is an established risk factor for Renal Cell Carcinoma (RCC), we investigated the association between plasma leptin levels and RCC risk.	19278051
Renal Insufficiency, Inflammation, Dyslipidemias	Altered Intercellular Communication	It specifically addressed the hypotheses that renal dysfunction in these patients may associate with the presence of insulin resistance, dyslipidaemia, uric acid levels and/or current levels of systemic inflammation.	19279016
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic inflammation contributes to the development and progression of chronic kidney disease (CKD).	19279127
Nephritis	Altered Intercellular Communication	There are currently no specific markers of renal inflammation.	19279127
Renal Insufficiency, Nephritis	Altered Intercellular Communication	Thus, we investigated the impact of progressive renal dysfunction and renal inflammation on plasma and urinary ET-1 concentrations.	19279127
Inflammation, Chronic ulcerative colitis	Altered Intercellular Communication	Severity of inflammation as a predictor of colectomy in patients with chronic ulcerative colitis.	19279411
Arterial Stiffness, Inflammation, Endothelial dysfunction, ETV3 wt Allele	Altered Intercellular Communication	How MetS increases CVD risk is incompletely understood, but increasing arterial stiffness is one candidate link, which in turn could be explained by (low-grade) inflammation, endothelial dysfunction (ED) or insulin resistance (IR).	19279658
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Additionally, the increase in stiffness was not explained by inflammation, ED or IR and suggests that stiffening of the muscular arteries in MetS may not be the consequence of these phenomena.	19279658
Whipple Disease, Myocarditis	Altered Intercellular Communication	Whipple's disease is a multisystem disease that can affect the heart with predominantly endocardial and pericardial involvement and, less often, myocardial inflammation.	19279994
Inflammation, Weight decreased, Overweight	Altered Intercellular Communication	Addition of aerobic exercise to a weight loss program increases BMD, with an associated reduction in inflammation in overweight postmenopausal women.	19280097
Inflammation, Weight decreased	Altered Intercellular Communication	Increased inflammation and weight loss are associated with a reduction in bone mineral density (BMD).	19280097
Inflammation, Weight decreased, Overweight	Altered Intercellular Communication	Our findings suggest that the addition of aerobic exercise is recommended to decrease inflammation and increase BMD during weight loss in overweight postmenopausal women.	19280097
Acute inflammation, Multilocular Thymic Cyst	Altered Intercellular Communication	We describe a case of multilocular thymic cyst with severe acute inflammation.	19280956
Inflammation	Altered Intercellular Communication	Histological examination of the resected specimen revealed that the prominent thinning in the arterial wall, however, there was no evidence of specific chronic inflammation.	19280961
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Arterial oxygen tension, oxygen delivery to tissue, and systemic inflammation are recognized as pivotal factors in the progression of chronic obstructive pulmonary disease (COPD).	19281089
Inflammation, Non-Small Cell Lung Carcinoma, Cachexia	Altered Intercellular Communication	The aim of this study was to detect the role of ghrelin in cachexia and systemic inflammation of advanced NSCLC patients as well as its role as a diagnostic and prognostic tool.	19282046
Inflammation, Crohn Disease	Altered Intercellular Communication	Evaluation of diffusion-weighted MR imaging for detection of bowel inflammation in patients with Crohn's disease.	19282206
Inflammation, Transverse colon, Rectum and sigmoid colon	Altered Intercellular Communication	Two radiologists reviewed diffusion-weighted images and ADC maps to evaluate for inflammation in each bowel segment (terminal ileum, cecum, ascending colon, transverse colon, descending colon, and rectosigmoid colon) and measured the ADC values of each bowel segment.	19282206
Inflammation	Altered Intercellular Communication	DWI detected inflammation in 18 of 19 segments (94.7%) and showed normal results in 28 of 34 segments (82.4%).	19282206
Inflammation	Altered Intercellular Communication	On diffusion-weighted images, bowel segments with inflammation revealed higher signal compared to normal segments.	19282206
Inflammation, Crohn Disease	Altered Intercellular Communication	DWI with parallel imaging is a feasible technique for the detection of inflammation in patients with Crohn's disease.	19282206
Inflammation, physiopathological, Peripheral arterial occlusive disease	Altered Intercellular Communication	Peripheral arterial occlusion disease (PAOD) is caused mainly by chronic inflammation and endothelium dysfunction, and is often treated with cilostazol.	19282610
Atherogenesis, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Cilostazol can decrease hs-CPR and sCD40L levels and increase that of adiponectin, and then delay the progression of atherogenesis and chronic inflammation in type 2 diabetics, especially those with PAOD.	19282610
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Homocysteine has been also linked to inflammation in rheumatoid arthritis (RA).	19283524
Rheumatoid Arthritis, Calcification of coronary artery, Inflammation	Altered Intercellular Communication	Increasing rheumatoid arthritis disease severity was associated with a higher prevalence and greater extent of coronary artery calcification, potentially mediated through an atherogenic effect of chronic systemic inflammation.	19284547
Gastrointestinal inflammation, Villous atrophy	Altered Intercellular Communication	Validation study of villous atrophy and small intestinal inflammation in Swedish biopsy registers.	19284576
Gastrointestinal inflammation	Altered Intercellular Communication	We validated VA (Marsh 3) and small intestinal inflammation without VA (Marsh 1+2) in Swedish regional biopsy registers.	19284576
Inflammatory Bowel Diseases, Inflammation, Comorbidity	Altered Intercellular Communication	IBD was the most common comorbidity and occurred in 0.3% of biopsies with VA (1.6% in inflammation).	19284576
Inflammation, Gastrointestinal symptom	Altered Intercellular Communication	79% of the validated individuals with VA and 64% of those with inflammation had documented gastrointestinal symptoms prior to biopsy.	19284576
Refractory anemias, Inflammation, Blood Vessel	Altered Intercellular Communication	This study evaluated the serum levels of S100A9, S100A8, S100A12 and sRAGE in RA patients, to determine their relationship to inflammation and joint and vascular damage.	19284577
Inflammation	Altered Intercellular Communication	sRAGE and S100 proteins were associated not just with RA inflammation and autoantibody production, but also with classical vascular risk factors for end-organ damage.	19284577
Cardiovascular Diseases, Prostate carcinoma, prostatitis	Altered Intercellular Communication	Nonsteroidal anti-inflammatory drugs such as aspirin prevent cardiovascular disease and several prior studies suggest that nonsteroidal anti-inflammatory drugs also decrease prostate inflammation and prostate cancer risk.	19286210
Inflammation, Breast Carcinoma	Altered Intercellular Communication	The prognostic significance of inflammation and medullary histological type in invasive carcinoma of the breast.	19286369
Inflammation, Neoplasms, Medullary carcinoma	Altered Intercellular Communication	The prognostic significance of tumour associated inflammation, an important feature of medullary carcinomas, remains controversial.	19286369
Inflammation, Ductal Carcinoma, Medullary carcinoma	Altered Intercellular Communication	Medullary carcinoma did not have significantly different prognosis than grade 3 ductal carcinoma with prominent inflammation, but both had a better prognosis than grade 3 ductal carcinoma without prominent inflammation (P<0.0001 and P=0.03).	19286369
Inflammation, Ductal Carcinoma, Medullary carcinoma	Altered Intercellular Communication	Prominent inflammation is associated with a better prognosis, and may explain the better prognosis in medullary carcinoma compared with grade 3 ductal carcinoma without prominent inflammation.	19286369
Inflammation, Skin Basal Cell Carcinoma, Medullary carcinoma	Altered Intercellular Communication	Further studies are needed to investigate the difference in survival between medullary carcinoma and other forms of basal carcinomas and the role of inflammation in any such differences in behaviour.	19286369
Asthma	Altered Intercellular Communication	To investigate the role of arginase isozymes (ARG1 and ARG2) in AHR, we determined the protein expression of ARG1, ARG2, the NOS isozymes, and other proteins involved in l-arginine metabolism in lung tissues from asthma patients and in acute (3-wk) and chronic (12-wk) murine models of ovalbumin-induced airway inflammation.	19286931
Pancreatic Diseases, Pancreatitis, Primary malignant neoplasm	Altered Intercellular Communication	The EPHX1 Y113H variant is not associated with pancreatic diseases indicating that EPHX1 does not play a significant role in the initiation of pancreatic inflammation or cancer.	19287329
vascular inflammations, Granulomatosis with polyangiitis, Transmissible canine venereal tumor	Altered Intercellular Communication	Basophilic granular karyorrhectic necrosis was seen focally (52%) as was vascular inflammation (56%) raising the differential diagnosis of Wegener's granulomatosis or infectious granulomas.	19287460
Inflammation, Cardiac Arrhythmia	Altered Intercellular Communication	So it is probable that the inflammation could contribute to the genesis and the perpetuation of this dysrhythmia.	19288178
Inflammation, Impaired cognition	Altered Intercellular Communication	We propose that increased longevity with HIV-mediated chronic inflammation combined with the secondary effects of HAART may increase the risk of early brain aging as shown by intraneuronal accumulation of abnormal protein aggregates like amyloid beta (Abeta), which might participate in worsening the neurodegenerative process and cognitive impairment in older patients with HIV.	19288297
Pseudogout	Altered Intercellular Communication	Based on the recent findings that interleukin (IL)-1beta is involved in crystal-induced inflammation, the patient received anakinra, a specific IL-1 inhibitor, in order to treat an acute attack of pseudogout.	19289295
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Histopathologic examination of 12 patients showed findings consistent with NXG, including a bandlike pattern of necrobiotic granulomatous inflammation, atypical giant cells, cholesterol clefts, and plasma cells.	19289757
Multiple Myeloma, Inflammation	Altered Intercellular Communication	However, the skin lesions in NXG represent reactive inflammation and are not associated with the presence of monoclonal plasma cells or multiple myeloma.	19289757
Acute inflammation, Obesity	Altered Intercellular Communication	Resistin has been linked with obesity and hypothesized as a potential marker of insulin resistance in addition to being linked with acute inflammation.	19290012
Inflammation	Altered Intercellular Communication	The larvae, 3 in number, were observed in the bulbar conjunctiva, and following removal the symptoms of eye inflammation improved within a few hours.	19290093
HD Term Type, Inflammation, Occlusive vascular disease, Venoocclusive disease	Altered Intercellular Communication	Here we investigate the effects of a short-term folate treatment on some markers of chronic inflammation in two groups of HD patients with and without vascular occlusive disease (VOD).	19290406
Cessation of life, Inflammation, Airway Obstruction	Altered Intercellular Communication	Death was due to upper airway obstruction from acute and chronic inflammation.	19291454
Inflammation, Acute Coronary Syndrome, Diabetes Mellitus, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	To study the relationship between inflammation, diabetes and HbA(1)c levels in patients with acute coronary syndrome (ACS).	19291585
Chronic lung disease	Altered Intercellular Communication	Patients with chronic lung disease and chronic inflammatory conditions are frequently treated with steroids such as prednisone at doses that may exceed 2.5 mg a day for long durations.	19292188
Inflammation, Florid reactive periostitis	Altered Intercellular Communication	Florid reactive periostitis is the term used to describe a benign disease characterized by aggressive periosteal reaction and benign soft-tissue inflammation.	19292223
Inflammation	Altered Intercellular Communication	Histopathological examination of the granulation tissue showed non-specific inflammation.	19292304
Inflammation, Thrombocytopenia	Altered Intercellular Communication	Elevated AFP levels correlated positively with age, HAI inflammation score, ALT elevation, and thrombocytopenia.	19293036
Inflammation	Altered Intercellular Communication	Minimal endoscopic sinus surgery showed nonspecific chronic inflammation.	19293627
Adenoma, Cushing Syndrome, "Pituitary-dependent Cushings disease	Altered Intercellular Communication	A 43-year-old female reported with mild signs and symptoms of hypercortisolism, and initial hormonal tests and results of pituitary imaging (7-mm adenoma) were suggestive for Cushing's disease.	19294516
Inflammatory abnormality of the eye	Altered Intercellular Communication	Careful examination of ocular inflammation is important in monitoring systemic disease and treatment.	19294569
Inflammation, Dislocations	Altered Intercellular Communication	On the other hand, prostheses with synthetic material are more often complicated by dislocation and inflammation.	19294589
Inflammation, IL13 gene	Altered Intercellular Communication	Allergic rhinitis involves inflammation of the nasal passages.	19295239
Inflammation, Keratitis, Hyphema	Altered Intercellular Communication	Complications included anterior segment inflammation in 5 eyes (20%), neurotrophic keratitis in 2 eyes (8%), and hypotony in 3 eyes (15%) in the DCPC group and hyphema in 5 eyes (15%) and tube occlusion in 3 eyes (9%) in AGV group.	19295370
Inflammation, Helicobacter pylori, Epithelial, Intraepithelial Lymphocytosis, Intestinal metaplasia	Altered Intercellular Communication	Histologic features including active or chronic inflammation, surface epithelial injury, intraepithelial lymphocytosis, intestinal metaplasia, and Helicobacter pylori, and measurement of thickness of subepithelial collagenous band were evaluated in gastric biopsies.	19295410
Inflammation	Altered Intercellular Communication	Foci of high-grade squamous neoplastic proliferation, inflammation, and a paratubal cyst were also present on the pathology specimen.	19295927
Inflammation, Chronic lung disease	Altered Intercellular Communication	The abnormal regulation of neutrophil apoptosis may contribute to the ineffective resolution of inflammation in chronic lung diseases.	19296848
Inflammation, Dilated Cardiomyopathy Pathway, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	High prevalence of chronic myocarditis in dilated cardiomyopathy referred for left ventriculoplasty: expression of tenascin C as a possible marker for inflammation.	19297005
Cholecystitis	Altered Intercellular Communication	We performed PTGBA (percutaneous transhepatic gallbladder aspiration) on the same day, and the gallbladder inflammation was improved.	19297956
Inflammation	Altered Intercellular Communication	Nuclear expression of BCL10 in infiltrating lymphocytes was a common occurrence in pSS minor salivary glands indicating it as a possible marker of autoimmune induced chronic inflammation.	19298243
Inflammation, Docetaxel Lipid Microspheres	Altered Intercellular Communication	The fact that inflammation in DLE generally involves the bulge area of the follicles raises the possibility that damage to the stem cells of the bulge region may be one process leading to the permanent loss of follicles.	19298282
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Oxidation, inflammation and apoptosis are involved in the aetiology and pathology of osteoarthritis (OA).	19298533
Vasculitis, CTCAE, Behcet Syndrome, Choroiditis	Altered Intercellular Communication	Choroidal inflammation could often play a primary etiological role during posterior vasculitis in Behcet's disease.	19299906
Inflammation, Behcet Syndrome	Altered Intercellular Communication	Echographic detection of choroidal thickening in patients with Behcet's disease not presenting with retinal alterations or visual symptoms could represent a useful way to detect an early inflammation, in order to start a proper therapy and to influence the final visual prognosis.	19299906
Inflammation, Disorder of the optic nerve	Altered Intercellular Communication	Their medical records were examined with particular emphasis on the location of the paranasal mucoceles, presence of inflammation (mucocele vs. pyelocele), presence of optic neuropathy, and final visual outcome.	19300156
Inflammation, Squamous cell carcinoma, SERPINB3 wt Allele	Altered Intercellular Communication	One main etiology for oral squamous cell carcinoma (OSCC) is inflammation.	19300368
Inflammation, Carcinogenesis	Altered Intercellular Communication	Inducible nitric oxide synthase (iNOS), vascular endothelial growth factor (VEGF) and cyclooxygenase-2 (COX-2) are the important molecules showing close relation to not only inflammation but also carcinogenesis and angiogenesis.	19300368
Inflammation	Altered Intercellular Communication	Ultrasmall superparamagnetic iron oxide (USPIO)-enhanced MRI has been shown to be a useful modality to image activated macrophages in vivo, which are principally responsible for plaque inflammation.	19300987
Inflammation, Hypoxia	Altered Intercellular Communication	The oxygen-regulated transcription factor subunit hypoxia inducible factor-1alpha (HIF-1alpha) is involved in angiogenesis, energy metabolism, cell survival, and inflammation.	19302222
Inflammation, selenium	Altered Intercellular Communication	Active and chronic inflammation were also significantly different between SE and BM (P < 0.0001) but not during further progression in the sequence.	19302222
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Histological data were available for 41 out of 81 patients before treatment, and the degree of fibrosis, inflammation and steatosis was assessed.	19302338
Inflammation, Clostridium difficile colitis	Altered Intercellular Communication	Pseudomembranous disease (ligneous inflammation) of the female genital tract, peritoneum, gingiva, and paranasal sinuses associated with plasminogen deficiency.	19302964
Inflammation	Altered Intercellular Communication	Pseudomembranous disease (or ligneous inflammation) is a rare condition characterized by accumulations of fibrin-rich eosinophilic material.	19302964
Gingivitis	Altered Intercellular Communication	Here, we report an unusual case of a 33-year-old woman who initially presented with gingival inflammation.	19302964
Inflammation, Postoperative infection	Altered Intercellular Communication	The risk of postoperative infection and delayed wound healing is high because of thick scar formation and persistent inflammation.	19303831
Inflammation, Necrosis	Altered Intercellular Communication	In three cases, a second salvage operation was necessary because of flap necrosis that was caused by unreliable recipient vessels resulting from scar formation and persistent inflammation.	19303831
Cataract, Inflammation	Altered Intercellular Communication	Objective assessment of inflammation after cataract surgery: comparison of 3 similar intraocular lens models.	19304088
Acute inflammation	Altered Intercellular Communication	To compare postoperative inflammation in patients receiving 1 of 3 AcrySof intraocular lenses (IOLs): MA60AC (Group 1), SA60AT (Group 2), or SN60AT (Group 3).	19304088
Inflammation, Arteriosclerosis, Hypertension, CTCAE	Altered Intercellular Communication	Arteriosclerosis and nonspecific inflammation are prevalent in patients with essential hypertension, and CRP with the cutoff value of 3.85 mg/L may serve as a sensitive indicator for arteriosclerosis diagnosis in these patients.	19304543
Trachoma , Inflammation	Altered Intercellular Communication	Photographic assessment is a useful technique, but in comparison with clinical assessment it can result in overestimation of scoring for trachoma for inflammation.	19304582
Inflammation, Specimen Type - Fistula	Altered Intercellular Communication	The patients were separated into two groups: group 1 included women with a pathologically proven colosalpingeal fistula, and group 2 included those who had contiguous periadnexal inflammation without a fistula.	19304701
Inflammation, Restless Legs Syndrome	Altered Intercellular Communication	Nor was there histological indication of any significant inflammation or concurrent ongoing pathology in these RLS cases.	19307154
Inflammatory Bowel Diseases, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Susceptibility to inflammatory bowel diseases depends upon interactions between the genetics of the individual and induction of chronic mucosal inflammation.	19307459
Inflammation, Electrocardiogram: left ventricle hypertrophy (finding), Left Ventricular Hypertrophy	Altered Intercellular Communication	Inflammation is an independent risk factor for high blood pressure, and as a consequence inflammatory cytokines could be related with left ventricular hypertrophy (LVH).	19308030
Degenerative polyarthritis	Altered Intercellular Communication	Human glycoprotein of cartilage (YKL-40) synthesizes chondrocytes and synovial cells in inflammatory conditions or remodels the outer cell matrix in osteoarthritis.	19308408
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Altered iron metabolism, inflammation, transferrin receptors, and ferritin expression in non-small-cell lung cancer.	19308738
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	The involvement of iron and inflammation parameters on overall survival in non-small-cell lung cancer (NSCLC) patients was studied.	19308738
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Therefore, we conclude that elevated serum ferritin in sera of NSCLC patients is the result of inflammation and oxidative stress rather than body iron overload.	19308738
Idiopathic achalasia of esophagus	Altered Intercellular Communication	Idiopathic achalasia is a rare disorder of the oesophagus of unknown aetio-pathogenesis characterized by a myenteric inflammation, aperistalsis and insufficient lower oesophageal sphincter relaxation.	19309439
Catheter-Related Inflammation	Altered Intercellular Communication	These findings suggest that CXCL12 contributed to tumor-related inflammation by inducing the accumulation of CXCR4-expressing cells with regulatory T cell markers around MM.	19309551
Inflammation	Altered Intercellular Communication	Pathological repair of chronic inflammation leads to airway remodeling.	19317336
Inflammation, Mucosal ulcer	Altered Intercellular Communication	There was however evidence of chronic inflammation and small bowel mucosal ulceration.	19317929
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Dietary intake of long-chain omega-3 (LC n-3) polyunsaturated fatty acids may reduce inflammation and in turn decrease risk of prostate cancer development and progression.	19318492
Carcinogenesis, prostatitis	Altered Intercellular Communication	Our findings support the hypothesis that LC n-3 may impact prostate inflammation and carcinogenesis through the COX-2 enzymatic pathway.	19318492
Inflammation	Altered Intercellular Communication	These data suggest that early intervention to prevent bile acid aspiration may reduce the intensity of neutrophilic inflammation in intubated and mechanically ventilated patients in the ICU.	19318678
Inflammation, Postoperative Complications, Colorectal Carcinoma	Altered Intercellular Communication	Preoperative systemic inflammation predicts postoperative infectious complications in patients undergoing curative resection for colorectal cancer.	19319134
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The presence of systemic inflammation before surgery, as evidenced by the glasgow prognostic score (mGPS), predicts poor long-term survival in colorectal cancer.	19319134
Inflammation, Asthma	Altered Intercellular Communication	Assessment of inflammation based on the release of oxygen radicals by granulocytes in chronic uncontrolled asthma.	19319447
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Chronic inflammation is known to occur in the brains of Alzheimer's Disease (AD) patients, including the presence of activated microglia close to amyloid plaques.	19320004
Inflammation, Traumatic injury, Traumatic cataract	Altered Intercellular Communication	Useful vision can be restored in a proportion of traumatic cataracts through surgery, although sight-limiting complications, which may be related to the severity of the trauma or prolonged post op inflammation may be present, many are potentially treatable with further intervention.	19320414
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Inflammation plays a role in the pathogenesis of coronary atherosclerosis.	19320909
Sepsis, Typhlitis, Leukopenia, Necrosis	Altered Intercellular Communication	Neutropenic colitis is a digestive wall inflammation, preferentially localized in the ileo-caecal area and the right colon, which leads to necrosis and sepsis, and usually occurs in neutropenic patients treated by chemotherapy with an incidence of 6%.	19321239
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	PARP-1 is recognized as coactivator of nuclear factor-kappaB and plays a role in the pathophysiology of diseases with low-grade systemic inflammation, such as chronic obstructive pulmonary disease (COPD) and type 2 diabetes (T2D).	19321592
Inflammation, Premature coronary artery atherosclerosis	Altered Intercellular Communication	Factor analysis of markers of inflammation and oxidation and echocardiographic findings in children with a positive family history of premature coronary heart disease.	19322601
Myositis, CTCAE 5.0	Altered Intercellular Communication	Although rare, cases of focal/localized myositis in which polymyositis-like muscle inflammation is present in only one muscle or extremity have also been reported.	19322621
Hemorrhage, Bronchiectasis, Hemoptysis, Tuberculosis, Pulmonary, Carcinoma of lung, Pneumonitis	Altered Intercellular Communication	Angiography during interventional treatment of 178 hemoptysis patients in the past 7 years confirmed that IPA hemorrhage resulted in hemoptysis in 25 patients (26 - 67 years old) who had: lung cancer (11 patients), bronchiectasis (11 patients), chronic lung inflammation (2 patients), and pulmonary tuberculosis (1 patient).	19323900
Inflammation, Fibrosis Assessment, Liver damage	Altered Intercellular Communication	There was a highly significant correlation between the positivity of NOSA and the degree of inflammation and hepatocellular injury (p = 0.001) and also with the degree of fibrosis (p < 0.0001).	19324518
Inflammation	Altered Intercellular Communication	This evolution might suggest a subacute inflammation phase within the nervous system, followed by a non-inflammatory phase.	19324868
Inflammation, Malignant Neoplasms, Neurologic (qualifier value)	Altered Intercellular Communication	The inflammation profile was similar in all antibody types, cancers or neurological syndromes of the PNS.	19324868
Inflammation	Altered Intercellular Communication	Reduction of T cell-derived ghrelin enhances proinflammatory cytokine expression: implications for age-associated increases in inflammation.	19324904
Inflammation	Altered Intercellular Communication	Intravenous infusion of IS causes oxidative stress and inflammation within peritoneal MCs which may impair viability of the peritoneum.	19325240
Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	Severe systemic inflammation (systemic inflammatory response syndrome) associated with cardiac surgery often leads to a worse short-term and long-term outcome.	19325469
Communicable Diseases, Inflammation	Altered Intercellular Communication	suspected infection, two or more criteria of systemic inflammation, and either systolic blood pressure <90 mm Hg after a fluid bolus or lactate >or=4 mmol/L.	19325482
Cataract, Intraocular inflammation	Altered Intercellular Communication	The most common complication was posterior capsule opacification and cataract development in seven eyes (25.9%) and in two eyes (25%, 2/8), respectively, the second complication was intraocular inflammation in six eyes (22.2%), the third complication was emulsification and dispersion and raised intraocular pressure in five eyes (18.5%), respectively.	19325573
Inflammation, Arthritis, Psoriatic	Altered Intercellular Communication	Interleukin-6 and soluble interleukin-2 receptor alpha-markers of inflammation in patients with psoriatic arthritis?	19327240
Inflammation, Dermatologic disorders	Altered Intercellular Communication	To evaluate a possible systemic effect of joint inflammation in contrast to skin disease only, by measuring IL-6 and IL-2sRalpha.	19327240
Inflammation, Arthritis	Altered Intercellular Communication	134 patients had inflammatory joint manifestations defined as peripheral arthritis and/or axial disease, of whom 37 had measurable inflammation, defined as ESR >25 mm/h and/or CRP >15 mg/L.	19327240
Inflammation, Dermatologic disorders, Arthropathy	Altered Intercellular Communication	Interleukin-6 was significantly higher in patients with joint disease and measurable inflammation ((median, Q1-Q3) 4.07, 0.92-14.60), and in patients without measured inflammation (1.22, 0.70-3.46), compared to patients with skin disease only (0.70, 0.70-1.73, p<0.001 and p=0.002 respectively).	19327240
Arthritis, Psoriasis	Altered Intercellular Communication	We found that patients with psoriasis and joint inflammation may have systemic effects that could be captured by serum measurements of IL-6.	19327240
Inflammation, Trigeminal nerve structure, Vasculitis, CTCAE, Ischemia	Altered Intercellular Communication	We presume that the TN was caused by compression of the trigeminal nerve from inflammation or ischemia secondary to vasculitis.	19327242
Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The British Society of Gastroenterology (BSG) suggests that a serum ferritin level	19327606
Inflammation, Takotsubo Cardiomyopathy	Altered Intercellular Communication	Importance of inflammation and neurohumoral activation in Takotsubo cardiomyopathy.	19327622
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Fever and markers of inflammation persisted despite 3 days of antibiotic therapy.	19328309
Hyperlipidemia, Myocardial Ischemia, Diabetes Mellitus, Endocrine System Diseases, Chronic liver disease, Hypertension, CTCAE, Epilepsy	Altered Intercellular Communication	Subjects with previous history of diabetes, hypertension, epilepsy, chronic renal or liver disease, hyperlipidemia, ischemic heart disease, endocrine diseases, or prolonged inflammatory conditions were excluded.	19328732
Inflammation, Obesity, Visceral, osteoclast activating factor	Altered Intercellular Communication	Thus, interventions targeting inflammation related to visceral obesity might help reducing the incidence of POAF.	19329496
Inflammation	Altered Intercellular Communication	Growing evidence suggests that NGAL may also be involved in cell survival, inflammation, and matrix degradation.	19329498
Inflammation, Calcinosis, Chronic Kidney Diseases	Altered Intercellular Communication	The expression of markers characteristic for calcification is not different in calcified aorta of CKD patients compared to controls, but in CKD patients, evidence of inflammation, transformation to an osteoblastic phenotype and reduced expression of transglutaminase are also found even in non-calcified aorta.	19329792
Neurogenic Inflammation, Discitis	Altered Intercellular Communication	In 13 of them (6.2%), a urogenital inflammation caused the spondylodiscitis.	19330316
Inflammation, Hyperplasia	Altered Intercellular Communication	Microscopically, superficial chronic inflammation with hyperplastic reactive changes and damaged surface was observed.	19330735
Inflammation, Malignant neoplasm of larynx	Altered Intercellular Communication	Galectin-1 has been found to modulate lymphocyte invasion in inflammation and to be involved in angiogenesis in models, thus prompting examination of its clinical relevance in laryngeal cancer.	19331133
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Magnetic resonance imaging in osteoarthritis: which method best reflects synovial membrane inflammation?	19332177
Inflammation	Altered Intercellular Communication	Chondral lesions and SM inflammation were macroscopically graded and SM biopsies performed for microscopic scoring.	19332177
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The three MRI approaches used here provided highly reproducible information on SM inflammation near the patella in knee OA.	19332177
Inflammation, Pain Distress Question, Synovitis, Conjunctival hyperemia, Degenerative polyarthritis	Altered Intercellular Communication	Compared to SMV, MRI synovitis score seems sufficient to assess synovial inflammation but high SMV is an appropriate indicator of vascular congestion, and low SMV reflects pain in knee OA.	19332177
Inflammation, CAV1 gene, Dental Plaque	Altered Intercellular Communication	The mechanism may be due to increased inflammation resulting in increased plaque burden suggesting a relationship between the immune basis of cellular rejection and CAV.	19332257
Celiac Disease, Gluten, IGA Glomerulonephritis, Inflammation	Altered Intercellular Communication	It is concluded that approximately one-third of our IgAN patients have a rectal mucosal sensitivity to gluten, but without signs of coeliac disease, and we hypothesize that such sub-clinical inflammation to gluten might be involved in the pathogenesis of IgAN in a subgroup of patients.	19332868
Inflammation, Spanish Language, Synovitis, Refractory anemias, Tumor necrosis	Altered Intercellular Communication	Despite a similar degree of overall joint inflammation in SpA and RA, SpA synovitis displayed strongly reduced SF levels of M1-derived, but not M2-derived, mediators, such as tumor necrosis factor alpha (TNFalpha), IL-1beta, IL-12p70, and interferon-gamma-inducible protein 10.	19333931
Refractory anemias, Arthritis	Altered Intercellular Communication	SF levels of M1-derived mediators correlated well with peripheral joint inflammation in RA, but neither these mediators nor IL-1alpha and IL-17 did so in SpA.	19333931
Cluster, Inflammation, Pain Distress Question, Gout	Altered Intercellular Communication	Cluster analysis and multidimensional scaling showed that these items clustered into 5 concepts (joint inflammation, severity of symptoms, stereotypical nature, pain, and gout archetype) distributed along 2 dimensions (objective to subjective features and general features to specific features of gout).	19333981
Refractory anemias, Rheumatoid Arthritis, Periodontitis	Altered Intercellular Communication	Rheumatoid arthritis (RA) and periodontitis are common chronic inflammatory conditions.	19335072
Inflammation, Periodontitis, Alveolar Bone Loss	Altered Intercellular Communication	Chronic periodontitis (CP) exhibits inflammation and alveolar bone loss, and severe forms of periodontitis are suggested to have a genetic basis.	19335080
Inflammation, Fibrosis Assessment, Alveolar damage	Altered Intercellular Communication	Postmortem examination showed extensive organ fibrosis, including severe diffuse alveolar damage and parenchymal fibrosis, and a notable lack of potentially treatable tissue inflammation.	19337287
Inflammation, Osteoporosis	Altered Intercellular Communication	Short leukocyte telomere length (TL), low BMD, and osteoporosis have been associated with increased inflammation.	19338455
Acute infectious disease, Bipolar Disorder	Altered Intercellular Communication	After adjustments for age, sex, acute infection and chronic inflammatory conditions, very high CRP was associated with lower social position, depressive symptoms, physical inactivity, smoking, and alcohol abstinence.	19339014
Inflammation, Nerve Degeneration	Altered Intercellular Communication	The relation between inflammation and neurodegeneration in multiple sclerosis brains.	19339255
Inflammation, MS gene, Nerve Degeneration	Altered Intercellular Communication	Some recent studies suggest that in progressive multiple sclerosis, neurodegeneration may occur independently from inflammation.	19339255
Inflammation, MS gene	Altered Intercellular Communication	We found that pronounced inflammation in the brain is not only present in acute and relapsing multiple sclerosis but also in the secondary and primary progressive disease.	19339255
Diffuse Axonal Injury, Inflammation, MS gene	Altered Intercellular Communication	A highly significant association between inflammation and axonal injury was seen in the global multiple sclerosis population as well as in progressive multiple sclerosis alone.	19339255
Inflammation, MS gene, Nerve Degeneration	Altered Intercellular Communication	Our study suggests a close association between inflammation and neurodegeneration in all lesions and disease stages of multiple sclerosis.	19339255
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Role of TNF-a, sTNF-R55 and sTNF-R75 in inflammation of acute exacerbations of chronic obstructive pulmonary disease.	19339767
Tumor necrosis, Chronic Obstructive Airway Disease, Inflammation	Altered Intercellular Communication	Although some recent studies have demonstrated the important role of tumor necrosis factor-a (TNF-a) and soluble TNF receptors (sTNF-R) in inflammation of chronic obstructive pulmonary disease, the exact roles of TNF-a and sTNF-R as well as their interaction remained unclear.	19339767
Inflammation	Altered Intercellular Communication	It was local inflammation but not systemic inflammation that was closely related to airflow limitation.	19339767
Hyperglycemia, Inflammation	Altered Intercellular Communication	Hyperglycaemia caused by stress and inflammation is common during critical illness.	19340390
Lewy Bodies, Inflammation	Altered Intercellular Communication	In Lewy body disease, inflammation is discussed to be involved in the pathophysiological cascade.	19340392
Communicable Diseases, Inflammation, Otosclerosis	Altered Intercellular Communication	Histologic otosclerosis exhibits a strong correlation with MV presence in the bone as a sign of persistent MV infection and related inflammation with TNF-alpha release.	19340443
Inflammation, Thrombocytopenia, Leukopenia, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Except for high parameters of inflammation, leucopenia and thrombocytopenia, all immunological and laboratory tests for SLE were negative in the onset of the disease.	19341232
Inflammation, Dental Plaque, Ischemia	Altered Intercellular Communication	Choline has been identified as a promising marker of coronary inflammation, plaque destabilisation and ischaemia.	19341718
Tissue damage, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	CRP is a well-known marker of inflammation and tissue damage, widely recognized as a risk predictor of cardiovascular and coronary heart diseases.	19341863
Inflammation	Altered Intercellular Communication	Substantial evidence suggests inflammation marked by elevated IL-6 levels as a key pathophysiologic factor that contributes to frailty.	19342252
Inflammation	Altered Intercellular Communication	These findings suggest upregulated monocytic expression of CXCL-10 as an important molecular mechanism that contributes to inflammation activation in frail older adults.	19342252
Inflammation, Hypertensive (finding), Endothelial dysfunction, diabetic	Altered Intercellular Communication	Endothelial dysfunction, a common feature among hypertensive and type-2 diabetic patients, is associated with inflammation, increased levels of circulating soluble adhesion molecules (SAM), and urinary albumin excretion.	19342863
Myocarditis	Altered Intercellular Communication	Myocardial inflammation and non-ischaemic heart failure: is there a role for C-reactive protein?	19343415
Cystic Lesion, Swelling, Dacryoadenitis	Altered Intercellular Communication	Computed tomography scan revealed a cystic lesion in the preseptal tissues with associated soft tissue swelling and lacrimal gland inflammation.	19343973
Vascular lesions, Encounter due to puberty	Altered Intercellular Communication	The importance of development of such vascular lesions at puberty, due to hormonal changes and increased estrogen levels, is highlighted.	19343976
Communicable Diseases, Inflammation	Altered Intercellular Communication	During the 4-year observation period, no complications were recorded, no implants were lost, and there was no infection or inflammation.	19344031
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Inflammation predicts accelerated brachial arterial wall changes in patients with recent-onset rheumatoid arthritis.	19344530
Inflammation, physiopathological, atherosclerotic	Altered Intercellular Communication	However, early control of inflammation may reduce arterial dysfunction and thus the tendency for atherosclerotic progression.	19344530
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation scores improved at all time points, and systemic immunosuppressive medication was reduced in 3 of 7 patients taking this at the start of the trial.	19344827
Chronicity, Inflammation, Varicose Ulcer	Altered Intercellular Communication	Increased levels of TNFalpha in nonhealing venous leg ulcers, especially those of longer duration, implies that excessive inflammation may be causal in wound chronicity and suggests potential therapeutic alternatives.	19344978
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	Mesenchymal stem cells in rheumatoid synovium: enumeration and functional assessment in relation to synovial inflammation level.	19346219
Inflammation	Altered Intercellular Communication	To test this hypothesis, the frequency and multipotency of RA synovial MSCs was evaluated in relation to existing synovial inflammation.	19346219
Inflammation	Altered Intercellular Communication	Synovial inflammation was measured using the arthroscopic visual analogue score (VAS) and further validated using immunohistochemistry and flow cytometry.	19346219
Inflammation	Altered Intercellular Communication	In RA-MSCs, CD44 levels correlated negatively with inflammation and positively with chondrogenesis (r = -0.830 and r = 0.865, respectively).	19346219
Refractory anemias, Inflammation	Altered Intercellular Communication	Effective suppression of joint inflammation is therefore necessary for the development of autologous MSC treatments aimed at cartilage regeneration in RA.	19346219
Retinal Vein Occlusion	Altered Intercellular Communication	Analysis of inflammation- and atherosclerosis-related gene polymorphisms in branch retinal vein occlusion.	19347053
Inflammation	Altered Intercellular Communication	We examine the relationship between serum titer of anti-CagA-P antibody and gastric inflammation as well as the status of the CagA-P expression in gastric mucosa.	19347242
Inflammation, Sarcoidosis	Altered Intercellular Communication	Patients with sarcoidosis have elevated levels of several markers of inflammation.	19347743
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Inflammation is currently believed not only to influence clinical manifestations ofosteoarthrosis (OA) but also to be a key pathogenetic link in the chain reaction underlying progress of the disease.	19348302
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Patients with OA and signs of local inflammation undergo a change of algofunctional index and markers of inflammation, such as C-reactive protein (C-RP) and interleukin-6 (IL-6).	19348302
Degenerative polyarthritis, Pathology	Altered Intercellular Communication	Inflammation markers in patients with isolated disease of large joints are more affected than in women with OA and concomitant pathologies.	19348302
Osteoarthritis of hip, Inflammation	Altered Intercellular Communication	Increased levels of C-RP and IL-6 in women with gonarthrosis/coxarthrosis confirm the key role of inflammation in the progress of this OA variant.	19348302
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Elevated C-RP and IL-6 levels in patients with OA suggest chronic inflammation in patients with degenerative-dystrophic joint affection.	19348302
Degenerative polyarthritis, Inflammation, Affection	Altered Intercellular Communication	Aggressive action of inflammation mediators in isolated affection of large joints accounts for the predominance of catabolic processes over anabolic ones which leads to further progress of OA due to low efficiency of the recovery of cartilage tissue and activation of its destruction.	19348302
Inflammation, atherosclerotic, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation is a well recognized central component of atherosclerotic processes in chronic kidney disease.	19349293
ARCN1 gene, Inflammation	Altered Intercellular Communication	Inflammation, most likely involving IL-6, may contribute substantially to PH complicating COPD.	19349390
Inflammation, Acute myocardial infarction, Necrosis	Altered Intercellular Communication	To investigate urinary methylmalonic acid (uMMA) levels and their relationship with markers of myocyte necrosis and inflammation in patients with acute myocardial infarction (AMI).	19349725
Infarction, Inflammation	Altered Intercellular Communication	uMMA levels were elevated in patients with AMI and, as such, may be a candidate biochemical indicator of larger infarct size and enhanced inflammation in patients with AMI.	19349725
Granulomatous inflammation, Typhoid Fever	Altered Intercellular Communication	Typhoid fever may be considered as one of the causes of the differential diagnoses of granulomatous inflammation of the small intestine.	19349729
Inflammation	Altered Intercellular Communication	For the general surgeon, open cholecystectomy is typically performed when a great degree of inflammation precludes safe laparoscopic removal.	19350862
Inflammation, Injury of bile duct	Altered Intercellular Communication	The degree of inflammation can also lead to an unacceptable risk of common bile duct injury during the dissection of the triangle of Calot.	19350862
Inflammation	Altered Intercellular Communication	Our data suggest that partial cholecystectomy in the setting of severe inflammation is a reasonable operation with few long-term sequelae, good clinical results, and satisfactory symptom relief.	19350862
Xanthogranulomatous cholecystitis, Xanthogranulomatous inflammation	Altered Intercellular Communication	Diagnosis of xanthogranulomatous mastitis can be made by excluding other diseases that elicit xanthogranulomatous inflammation in the breast.	19351366
Tumor necrosis, Obesity, Abdominal, Inflammation	Altered Intercellular Communication	Impaired preadipocyte differentiation in human abdominal obesity: role of Wnt, tumor necrosis factor-alpha, and inflammation.	19351711
Inflammation, Obesity	Altered Intercellular Communication	An Ask1-MKK4-p38MAPK/JNK pathway reflects adipocyte stress associated with adipose tissue inflammation, linking visceral adiposity to whole-body insulin resistance in obesity.	19351724
Inflammation, Lymphoma	Altered Intercellular Communication	Etiology and pathogenesis of these NHLs are unknown, although there might be a possible association between chronic inflammation and lymphomas.	19352660
Gastrointestinal inflammation	Altered Intercellular Communication	We speculate that TGF-beta1 drives GATA-4 expression during intestinal inflammation, these two components cooperating to promote epithelial healing.	19353247
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Small airway mucous metaplasia and inflammation in chronic obstructive pulmonary disease.	19353346
Airway structure	Altered Intercellular Communication	Its relationship to small airway inflammation is poorly defined.	19353346
ARCN1 gene, Inflammation	Altered Intercellular Communication	CD3(+) and CD8(+) lymphocytic inflammation is related to small airway mucous metaplasia in COPD and may play a causative role in its development.	19353346
Supranuclear paralysis	Altered Intercellular Communication	A dysfunction of multiple neurotransmitter systems is assumed as a neurochemical basis of the akinetic-rigid syndrome of progressive supranuclear palsy (PSP).	19353726
Inflammation	Altered Intercellular Communication	In conclusion, probiotic administration in the elderly normalises the response to endotoxin, and modulates activation markers in blood phagocytes, and therefore may help reduce low-grade chronic inflammation.	19353762
Airway structure, Asthma	Altered Intercellular Communication	Exhaled breath condensate (EBC) pH has been proposed as a biomarker of airway inflammation and oxidative stress in asthma.	19353777
Airway structure	Altered Intercellular Communication	We also investigated the relationship between EBC pH and biomarkers of airway inflammation and oxidative stress.	19353777
Inflammation, Dyslipidemias, Diabetes Mellitus	Altered Intercellular Communication	Low-grade inflammation exists in Diabetes mellitus and it is positively related with dyslipidemia (except for HDL cholesterol) in diabetics.	19356332
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Tartrate-resistant acid phosphatase isoform 5a as an inflammation marker in end-stage renal disease.	19356371
Kidney Failure, Chronic, Inflammation, Malnutrition	Altered Intercellular Communication	End-stage renal disease (ESRD) is often complicated by chronic inflammation and malnutrition.	19356371
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	We tested whether serum tartrate-resistant acid phosphatase (TRACP) isoform 5a relates to other markers of inflammation in ESRD.	19356371
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Our findings suggest that TRACP 5a may be a useful marker to estimate the degree of inflammation in ESRD patients on chronic hemodialysis.	19356371
Communicable Diseases, Inflammation	Altered Intercellular Communication	Adverse events (AE) of infection or inflammation were recorded.	19356372
Communicable Diseases, Inflammation	Altered Intercellular Communication	Intra-patient Hb variability was greater in the presence of intercurrent conditions, including infection or inflammation (p = 0.0032), blood transfusion (p < 0.0001), hospitalization (p < 0.0001), or hospitalization for cardiovascular (CV) causes (p = 0.0012), than in their absence.	19356372
Lesion, Inflammation, Toxic effect, Demyelination	Altered Intercellular Communication	We suggest that lesions identified on MRI may be related to a combination of demyelination, inflammation and/or even small-vessel infarction due to local intimal lesions and clotting, secondary to eosinophilic toxicity.	19356842
Inflammation	Altered Intercellular Communication	Early patchy enhancement did not demonstrate statistically significant correlation with inflammation (P=.28).	19356874
Inflammation, Chronic disease	Altered Intercellular Communication	The role of inflammation is being considered in chronic diseases.	19356949
Limbic Encephalitis, Inflammation, T2 and Fluid Attenuated Inversion Recovery MRI, Neoplasms	Altered Intercellular Communication	Diagnoses in the 84 patients (mean age 42 years at MTLE onset) were: limbic encephalitis (LE), n = 23 (27%); HS (unrelated to inflammation), n = 18 (22%); tumours I/II(o), n = 12 (14%); amygdala lesions (increased volume and T2/FLAIR signal), n = 11 (13%); and other, n = 20 (24%).	19357127
Allergic asthma, Pulmonary Emphysema, Bronchitis, Eosinophilic inflammation	Altered Intercellular Communication	Five clusters were identified with the following characteristics: cluster 1: severe and markedly variable airflow obstruction with features of atopic asthma, chronic bronchitis and emphysema; cluster 2: features of emphysema alone; cluster 3: atopic asthma with eosinophilic airways inflammation; cluster 4: mild airflow obstruction without other dominant phenotypic features; and cluster 5: chronic bronchitis in nonsmokers.	19357143
Abnormality of the vasculature	Altered Intercellular Communication	Bronchoscopy depicted focal submucosal vascular abnormalities in three patients and only endobronchial inflammation in 32 (91%) patients.	19357153
Intradermal Route of Drug Administration, Inflammation, Anemia	Altered Intercellular Communication	Among females, the body iron model produced lower estimates of ID prevalence, better predicted anemia, and appeared to be less affected by inflammation than the ferritin model.	19357218
Inflammation, Hyperhomocysteinemia, Thrombosis, Fibrosis Assessment, Heart failure	Altered Intercellular Communication	Hyperhomocysteinemia, neurohormonal activation, inflammation and altered fibrinolysis have been linked to atherothrombosis as well as to myocardial fibrosis and heart failure.	19357531
Inflammation, Tumor Cell Invasion, Pneumonia	Altered Intercellular Communication	For autopsy-proven cases of Candida pneumonia, we required microscopic demonstration of yeast invasion in lung autopsy specimens that showed inflammation.	19357832
Gingivitis, Abscess, Hemorrhage	Altered Intercellular Communication	Intraoral examination revealed severe gingival inflammation, dental abscesses, pathological tooth mobility, bleeding upon probing and attachment loss around several primary teeth.	19358384
Inflammation, Atherosclerosis	Altered Intercellular Communication	We conclude that continuous infusion of uncontaminated nCRP in apoE (-/-) mice is not associated with increased atherosclerosis, does not alter systemic or local inflammation, and does not affect endothelial activation.	19359657
Inflammation, Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	The CXCL12/CXCR4 pathway, which is involved in biological phenomena such as inflammation, lymphoid homing and regeneration, may play an important role in tumor progression and distant metastasis, especially in organ-selective metastasis.	19360294
Inflammation, Hepatitis, Subretinal route, Hypopyon, Liver Cirrhosis	Altered Intercellular Communication	Three months prior, the patient had undergone liver transplantation for cirrhosis caused by hepatitis C. A slit-lamp examination revealed intense anterior chamber inflammation with hypopyon and fundoscopy showed a yellowish-white subretinal mass lesion in the inferior peripheral fundus.	19360381
hearing impairment, Fibrosis Assessment	Altered Intercellular Communication	Inflammation during the active stage of the disease and the subsequent fibrosis may cause conductive hearing loss of varying degrees.	19360433
Inflammation, Primary malignant neoplasm, Neoplasms, Ulcer, Intestines, Small	Altered Intercellular Communication	There were some longitudinal ulcer scars near the tumor, and the chronic inflammation in the small bowel appeared to be associated with the cancer development.	19360924
Inflammation, Angina, Unstable	Altered Intercellular Communication	Prognostic value of heart rate turbulence and its relation to inflammation in patients with unstable angina pectoris.	19361591
Inflammation	Altered Intercellular Communication	A relation between cardiac autonomic function and inflammation was shown in several clinical settings.	19361591
Inflammation, Cachexia	Altered Intercellular Communication	Protein-Energy Wasting and inflammation are the principal risk factors of haemodialysis complications.	19361965
Inflammation, Malnutrition	Altered Intercellular Communication	We evaluated the reliability of a simple and non expensive test, the Prognostic Inflammatory and Nutritional Index (PINI), for regular screening of maintenance haemodialysis (MHD) patients in order to detect early onset of inflammation and malnutrition.	19361965
Inflammation, Malnutrition	Altered Intercellular Communication	This simple test appears to be more sensitive and specific of the single components, and not expensive, so that it could be routinely used to identify patients with sub-clinical inflammation and/or malnutrition.	19361965
vascular inflammations	Altered Intercellular Communication	The objective was to investigate whether dietary intake of plant lignans in a free-living population was associated with markers of vascular inflammation and function.	19361969
vascular inflammations, Endothelial dysfunction	Altered Intercellular Communication	Higher MAT intakes in the context of a typical Northern Italian diet are associated to lower vascular inflammation and endothelial dysfunction, which could have some implications in CVD prevention.	19361969
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	To better understand the relationship between humoral and cellular markers of inflammation and postoperative atrial fibrillation (AF).	19362015
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	These results suggest that the inflammatory process in lung fibrosis may involve the coronary arteries as a part of a systemic inflammation rather than an idiopathic fibrotic disease confined to the lungs.	19362458
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	There was a strong association between inflammation and the metabolic syndrome independent to viral and bacterial infectious burden.	19362745
Granulomatous inflammation	Altered Intercellular Communication	These giant cells are often observed in granulomatous inflammation against a foreign material.	19362870
Inflammation, Fetus Small for Gestational Age, Malnutrition	Altered Intercellular Communication	Inflammation (serum C-reactive protein >or= 0.9 mg/dl) was present in 13 (25%) and malnutrition (SGA) in 16 (30.7%) patients.	19363697
Inflammation, muscle mass	Altered Intercellular Communication	A negative and independent association between muscle mass percentage (BIA) and inflammation was observed.	19363697
Weakness, Hypopituitarism, Anorexia	Altered Intercellular Communication	Patient 1 was a 54-year-old woman with weakness, loss of appetite, and a hormonal profile suggestive of hypopituitarism.	19364690
Inflammation, Sore to touch, Exanthema	Altered Intercellular Communication	On physical examination, he had no evidence of skin rash, inflammation, or abnormalities of the testes, although there was marked tenderness on palpation.	19364694
deficiency aspects, Sexual Dysfunction	Altered Intercellular Communication	For women, hormonal deficiency is not the unique cause of sexual dysfunction.	19365913
Inflammation, Congenital bronchogenic cyst	Altered Intercellular Communication	The majority of SPNs represent benign processes, including granulotmatous inflammation, bronchogenic cysts and hamartomata.	19365977
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Low-grade chronic inflammation in the relationship between insulin sensitivity and cardiovascular disease (RISC) population: associations with insulin resistance and cardiometabolic risk profile.	19366964
Inflammation	Altered Intercellular Communication	This study showed that low-grade chronic inflammation is associated with the cardiometabolic risk profile of a healthy population.	19366964
vascular inflammations, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Klotho-disrupted mice exhibit atherosclerosis and endothelial dysfunction, which led us to investigate the effect of the Klotho protein on vascular inflammation, particularly adhesion molecule expression.	19367378
Inflammation	Altered Intercellular Communication	Klotho may have a role in the modulation of endothelial inflammation.	19367378
Multilineage Dysplasia Present, Inappropriate ADH Syndrome, Leukemia, Myelocytic, Acute	Altered Intercellular Communication	Syndrome of inappropriate antidiuretic hormone secretion associated with acute myeloid leukemia with multilineage dysplasia.	19367383
Inflammation	Altered Intercellular Communication	These findings suggest chronic inflammation and tissue repair as etiological factors in the development of GCT-ST.	19367406
Inflammation, Atherosclerosis	Altered Intercellular Communication	Continuous exposure to high grade systemic inflammation may be linked to accelerated atherosclerosis.	19368280
Inflammation, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Chronic low-grade inflammation is a significant factor in the development of obesity associated diabetes.	19368716
Inflammation	Altered Intercellular Communication	We conclude that sub-clinical inflammation in T2DM may, in part, be mediated by circulating endotoxin.	19368716
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation in patients with asthma with high-fixed or low-fixed plus as-needed budesonide/formoterol.	19368965
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Growth arrest-specific gene 6 (GAS6) encodes a vitamin K-dependent protein that regulates inflammation, angiogenesis, and atherosclerotic plaque formation.	19369636
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Cardiovascular Diseases	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is recognized as a source of systemic inflammation and is associated with the development of cardiovascular disease.	19369691
Inflammation, Lymphadenitis	Altered Intercellular Communication	The three false positive PET/CT findings comprised chronic inflammation of mediastinal lymph nodes (n = 2) and anastomosis inflammation (n = 1).	19370780
Communicable Diseases, Inflammation	Altered Intercellular Communication	This is useful knowledge when CRP is used in the clinic for infection and inflammation status.	19372230
Inflammation, Hypertrophy	Altered Intercellular Communication	Resistin is associated with inflammation and insulin resistance and exerts direct effects on myocardial cells including hypertrophy and altered contraction.	19372460
Vitreous Hemorrhage, Intraocular inflammation, Retinal Detachment	Altered Intercellular Communication	Complications included transient vitreous hemorrhage (n = 3), transient intraocular inflammation (n = 3), localized, chronic retinal detachment (n = 1).	19373124
Intraocular inflammation	Altered Intercellular Communication	After DS, more postoperative adjustments were necessary to lower IOP than after TRAB (85 vs 9.5%, P<0.001), but 7 days after surgery, intraocular inflammation was higher after TRAB (245.8 vs 38.5 ph/ms, P<0.001).	19373262
Inflammation, Saint Lucia	Altered Intercellular Communication	Acute inflammation was diagnosed in 52% of OC and 28% of LC patients.	19376278
Inflammation	Altered Intercellular Communication	Peroxisome proliferator-activated receptor alpha (PPARalpha) activators reduce inflammation and oxidative stress.	19376321
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation plays an important role in the initiation and maintenance of atrial fibrillation (AF).	19376321
Inflammation, Fibrous	Altered Intercellular Communication	Inflammation and structural factors such as a thin fibrous cap, positive remodeling and large lipid pool have been established as factors associated with coronary plaque instability.	19376518
Inflammation	Altered Intercellular Communication	Dendritic cells (DC) represent an important and integral part of the immune system and are potent initiators of inflammation.	19376529
Peripheral Vascular Diseases, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Nitric oxide: link between endothelial dysfunction and inflammation in patients with peripheral arterial disease of the lower limbs.	19376804
Peripheral Vascular Diseases, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	To analyse the role of nitric oxide (NO) in peripheral arterial disease (PAD) and its association with inflammation and brachial artery flow-mediated dilation (BAFMD) as an estimation of endothelial dysfunction.	19376804
AURKAIP1 gene, Autoimmune Pancreatitis, Mikulicz Disease	Altered Intercellular Communication	It includes autoimmune pancreatitis (AIP), Mikulicz's disease, and many other inflammatory conditions affecting multiple organs.	19377901
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The mechanisms behind airway inflammation in chronic obstructive pulmonary disease (COPD) are still not well understood.	19378224
Hepatitis C	Altered Intercellular Communication	Malnutrition-inflammation complex syndrome and hepatitis C in maintenance hemodialysis patients.	19379150
Inflammation, Protein-Energy Malnutrition	Altered Intercellular Communication	Protein-energy malnutrition and inflammation are among the leading causes of poor outcome in hemodialysis patients.	19379150
Communicable Diseases, Hepatitis C	Altered Intercellular Communication	Hepatitis C virus (HCV) infection is accompanied by elevated proinflammatory mediators, also found in dialysis patients with malnutrition-inflammation complex syndrome.	19379150
Airway structure	Altered Intercellular Communication	FeNO measured offline is a useful biomarker for airway inflammation in large population-based studies.	19379527
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) is characterized by persistent inflammation of the nasal and paranasal mucosa with numerous emigrated leukocytes.	19379607
Inflammation	Altered Intercellular Communication	Naturally, other mechanisms such as cell inflammation and lack or incapacity of antioxidant enzymes also contribute to the variety of systematic distortions that characterize aging.	19379805
Myocarditis	Altered Intercellular Communication	Miniaturized extracorporeal circulation can be considered similar to off-pump surgery in terms of systemic inflammatory response, myocardial inflammation and damage, and early outcome.	19379993
Inflammation	Altered Intercellular Communication	It has clinical signs of severe local inflammation as a result of an exaggerated inflammatory response but neurogenic dysregulation also contributes to it.	19380284
Inflammation, Complex Regional Pain Syndromes	Altered Intercellular Communication	Although clinically appearing as inflammation in acute stages, local rather than systemic inflammatory responses seem to be relevant in CRPS.	19380284
Inflammation, deficiency aspects, Malignant Childhood Neoplasm, Communicable Diseases, Calciphylaxis, Obesity, Hypoalbuminemia, Weight decreased, Liver Cirrhosis	Altered Intercellular Communication	Analysis of this case and the 13 previously reported cases of nontraditional calciphylaxis identified the following patient characteristics that highlight clinical situations potentially predisposing to calciphylaxis: hypoalbuminemia, malignant neoplasm, systemic corticosteroid use, anticoagulation with warfarin sodium or phenprocoumon, chemotherapy, systemic inflammation, hepatic cirrhosis, protein C or S deficiency, obesity, rapid weight loss, and infection.	19380668
Cytomegalovirus Infections, Inflammation, Chlamydia, Endothelial dysfunction, Peripheral Vascular Diseases	Altered Intercellular Communication	Markers of Chlamydia pneumoniae and human cytomegalovirus infection in patients with chronic peripheral vascular disease and their relation to inflammation, endothelial dysfunction and changes in lipid metabolism.	19381484
Inflammation, Communicable Diseases, Chlamydia, Endothelial dysfunction, Peripheral Vascular Diseases	Altered Intercellular Communication	Our aim was to detect markers of Chlamydia pneumoniae (CPN) and human cytomegalovirus (HCMV) infection in patients with peripheral vascular occlusive disease and to follow markers of inflammation, endothelial dysfunction and lipid metabolism alteration in patients with active infection.	19381484
Hereditary Diseases, Inflammation, Abdominal Pain	Altered Intercellular Communication	Because the patient's mother complained about chronic and periodic abdominal pain with also persistently elevated inflammatory parameters, the differential diagnosis included hereditary disorders resulting in chronic inflammation.	19381634
Hereditary Autoinflammatory Diseases, Inflammation, Fever, CTCAE	Altered Intercellular Communication	Hereditary fever syndromes have to be considered in case of chronic unexplained inflammation even if fever is no presenting symptom.	19381634
ARCN1 gene, Inflammation	Altered Intercellular Communication	As COPD is driven by abnormal pulmonary and systemic inflammation, Toll-like receptors (TLRs) seem to be important.	19381722
Chronic disease of respiratory system, Inflammation, Colonization, Pneumocystis jiroveci	Altered Intercellular Communication	In patients with chronic respiratory disease, Pneumocystis jirovecii (P. jirovecii) colonization is observed, and may influence disease progression and systemic inflammation.	19383170
Inflammation, Neurosarcoidosis	Altered Intercellular Communication	MRI and CSF studies are sensitive in the detection of CNS inflammation but lack specificity, making the ascertainment of neurosarcoidosis a clinical challenge.	19383611
Inflammation	Altered Intercellular Communication	BSS offers a significant advantage over RL in terms of increase in corneal thickness and postoperative inflammation on the first postoperative day in patients undergoing phacoemulsification.	19384012
Inflammation, Anemia	Altered Intercellular Communication	Anemia persists in many patients following critical illness and is associated with ongoing inflammation, inappropriate erythropoietin response and poor marrow red cell production.	19384207
Inflammation, Reperfusion Injury	Altered Intercellular Communication	When used to prevent perioperative inflammation and ischemia-reperfusion injury, N-acetylcysteine may inadvertently impair hemostasis.	19384218
Inflammation	Altered Intercellular Communication	In the suture group, 44.4% of the patients presented inflammation after surgery compared to none in the glue group.	19384757
Inflammation, Pterygium Of Conjunctiva And Cornea	Altered Intercellular Communication	The use of fibrin glue in pterygium surgery reduces patient symptoms, inflammation and discomfort.	19384757
Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation due to previous operation may be a factor inducing opacification through increase of iron-binding capacity in the aqueous humour.	19384780
Inflammation, Rhabdomyolysis, Kidney Failure	Altered Intercellular Communication	Laboratory findings revealed signs of severe rhabdomyolysis and renal failure as well as elevated markers of inflammation.	19384813
Inflammation, Oliguria	Altered Intercellular Communication	It is possible that inflammation plays a role in volume decreases associated with normal aging, and that suppressing the inflammatory response moderates this decrease.	19386384
Refractory anemias, Inflammation, Osteopenia	Altered Intercellular Communication	This study provides strong evidence of a causal link between inflammation and bone loss in RA.	19386610
Inflammation	Altered Intercellular Communication	One variable that may have contributed to poor outcomes is low drug levels at the site of nerve inflammation.	19387178
Inflammatory abnormality of the eye, Scleritis	Altered Intercellular Communication	A 78-year-old otherwise healthy woman presented with sudden, severe painful ocular inflammation and marked injection of the right eye over a 3-day period, consistent with scleritis.	19387243
melanoma, Inflammation, Dental Plaque	Altered Intercellular Communication	The melanoma was treated with iodine 125 plaque radiotherapy, and during surgery, the temporal sclera was markedly edematous and the orbital tissue was fibrotic, presumed related to inflammation.	19387243
Inflammation, myocardial injury	Altered Intercellular Communication	The combination of elevated CRP and cTnI increased the risk of adverse cardiac events, demonstrating the additive impacts of active inflammation and myocardial injury on prognosis after SES implantation.	19387251
Colorectal Carcinoma	Altered Intercellular Communication	Comparison of the prognostic value of inflammation-based pathologic and biochemical criteria in patients undergoing potentially curative resection for colorectal cancer.	19387324
Inflammation	Altered Intercellular Communication	The results of the present study suggest low peritumoral infiltrate (Klintrup criteria) and increased systemic inflammation (mGPS criteria) are linked through the cell-mediated immune system.	19387324
Inflammation, Carcinoma of lung	Altered Intercellular Communication	We studied the usefulness of the above parameter determination in differentiation between lung cancer and inflammation.	19388531
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The results suggest that activity of the chitotriosidase can not be used to differentiation between inflammation and cancer in lung.	19388531
Kidney Failure, Chronic	Altered Intercellular Communication	We hypothesized that CCR5 Delta 32 modulates inflammation-driven mortality in patients with ESRD.	19389855
Inflammation, Carcinogenesis	Altered Intercellular Communication	Further studies are needed to elaborate the role of inflammation in sporadic colorectal carcinogenesis.	19390125
Inflammatory Bowel Diseases, Miller Dieker syndrome, NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology, Chromosome Aberrations, Gastrointestinal inflammation	Altered Intercellular Communication	Although chromosomal abnormalities in bone marrow (BM) cells, such as trisomy 8, are risk factors for the development of inflammatory bowel diseases (IBD) as well as myelodysplastic syndrome (MDS), the mechanisms of how these cytogenetic abnormalities cause intestinal inflammation are poorly understood.	19390193
Inflammation	Altered Intercellular Communication	The negative correlation between the ejection fraction of the gallbladder and mucin concentration of gallbladder bile suggests that chronic inflammation of the gallbladder wall is associated with both an impaired motility of the gallbladder and increased mucin release into gallbladder bile.	19390195
Inflammation	Altered Intercellular Communication	In patients who have had dilatation in the past, inflammation between the esophageal mucosal and muscular layers may make it difficult to perform myotomy.	19390272
vascular inflammations, Hypertension, CTCAE, Atherosclerosis	Altered Intercellular Communication	Circulating angiopoietin-2 in essential hypertension: relation to atherosclerosis, vascular inflammation, and treatment with olmesartan/pravastatin.	19390459
vascular inflammations, Hypertension, CTCAE, Cardiovascular Diseases	Altered Intercellular Communication	We have earlier shown that angiotensin II receptor blocker (ARB) reduces mediators of vascular inflammation in hypertension and cardiovascular disease.	19390459
Inflammation, Left Ventricular Hypertrophy	Altered Intercellular Communication	Chronic subclinical inflammation including the TNFR1-associated system may contribute to LVH.	19390513
Inflammation, Obesity	Altered Intercellular Communication	Neutrophil activation in morbid obesity, chronic activation of acute inflammation.	19390527
Obesity	Altered Intercellular Communication	Moreover, because neutrophils have a short life span, this indicates that the chronic inflammatory condition associated with morbid obesity is characterized by a continuous activation of the innate immune system.	19390527
Celiac Disease, Inflammation, Crypt hyperplasia, Villous atrophy	Altered Intercellular Communication	Celiac disease (CD) is characterized by villous atrophy with crypt hyperplasia and inflammation of the small intestinal mucosa leading to disturbed epithelial transport.	19391064
Inflammation	Altered Intercellular Communication	To assess whether RDW is associated with plasma markers of inflammation since the mechanism(s) underlying this association remain unknown.	19391664
Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	Our findings implicate oxidized Hb as a possible antigenic target of cell-mediated immune responses contributing to inflammation in the pathogenesis of carotid atherosclerosis.	19393213
Familial neurocardiogenic syncope, Vulvar Vestibulitis	Altered Intercellular Communication	Subsurface inflammation of the introitus, vagina, and cervix only was detected uniquely in women with vulvar vestibulitis syndrome (VVS).	19393601
Inflammation, Familial neurocardiogenic syncope, Lichen Sclerosus et Atrophicus	Altered Intercellular Communication	A subset of women presenting with VVS exhibited subclinical inflammation of the vulva vestibule and vagina (designated VVS/lichen sclerosus subgroup).	19393601
Inflammation, Vulva	Altered Intercellular Communication	Enhanced visualization of the genital epithelial subsurface with cross-polarized light may assist in diagnosing subclinical inflammation in vulvar conditions heretofore characterized as sensory syndromes.	19393601
Inflammation, Corneal edema	Altered Intercellular Communication	The visual acuity, degree of corneal edema, inflammation, and intraocular pressure (IOP) were measured.	19393885
Inflammation, PDR gene	Altered Intercellular Communication	Appropriate control of postsurgical inflammation is necessary in phacovitrectomy for PDR.	19393886
Inflammation, Kidney Failure, Acute, Blood Coagulation Disorders, Aortic Aneurysm, Thoracoabdominal	Altered Intercellular Communication	Systemic inflammation, coagulopathy, and acute renal insufficiency following endovascular thoracoabdominal aortic aneurysm repair.	19394543
Aneurysm, Malignant Neoplasms	Altered Intercellular Communication	Although previous studies have shown that PET/CT might affect patient selection based on aneurysm wall inflammation, our preliminary results show a big impact on patient management as a result of the sensitivity of PET/CT for detecting malignancy.	19394556
Inflammation, Comorbidity, Chronic Kidney Diseases	Altered Intercellular Communication	Patients with chronic kidney disease stage 5 have high comorbidity and are prone to inflammation that may contribute to the high cardiovascular mortality risk.	19394732
Inflammation, Comorbidity	Altered Intercellular Communication	Comorbidity and clinical events are strongly associated with inflammation in hemodialysis patients.	19394732
Rheumatoid Arthritis, Acute inflammation, Lymphopenia, Lupus Erythematosus	Altered Intercellular Communication	Autoantibodies against galectin-8: their specificity, association with lymphopenia in systemic lupus erythematosus and detection in rheumatoid arthritis and acute inflammation.	19395456
Autoimmune Diseases, Acute inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	This study thus establishes occurrence of specific anti-Gal-8 autoantibodies in autoimmune rheumatic diseases and in acute inflammation, with an apparent association to a clinical subset in SLE.	19395456
Inflammation, Lower Urinary Tract Symptoms, Benign prostatic hypertrophy	Altered Intercellular Communication	Inflammation may play a role in the development of benign prostatic hyperplasia and/or lower urinary tract symptoms (LUTS).	19395697
Mixed Salivary Gland Tumor, Adenolymphoma, Inflammation	Altered Intercellular Communication	The results of ultrasound-guided fine-needle aspiration biopsy (FNAB) (n = 9) and core-needle biopsy (CNB) (n = 3) were Warthin tumor in 10 cases, and pleomorphic adenoma and chronic inflammation in one each.	19396445
Mixed Salivary Gland Tumor, Adenolymphoma, Inflammation	Altered Intercellular Communication	SUV(max) was 7.0-21.0 g/mL (average 13.7 g/mL) for Warthin tumor, 6.8 g/mL for pleomorphic adenoma, and 7.3 g/mL for chronic inflammation.	19396445
Inflammation	Altered Intercellular Communication	Each FDG-avid focus corresponded to ovoid (n = 11) or lobulated (n = 1) hypoechoic mass on grayscale ultrasonography (US) and hypervascular mass, except one with chronic inflammation, on power Doppler (PD) US.	19396445
Sepsis, Inflammation	Altered Intercellular Communication	TREM-1 is up-regulated in PBMC of AC patients, and has higher sensitivity and specificity than other clinical inflammation markers, suggesting its importance in AC-induced sepsis.	19396532
Intraocular inflammation, Neoplasms	Altered Intercellular Communication	No significant tumor neovascularization or intraocular inflammation was noted.	19396801
Inflammation, Dermatitis	Altered Intercellular Communication	The lesion was initially thought to be an area of lichenified dermatitis; however, treatment with even super-potent topical corticosteroids did not significantly improve the inflammation.	19397564
Abdominal wall structure, Rupture	Altered Intercellular Communication	The increment of MMPs in the absence of a counterbalance by TIMPs, together with an ongoing de-regulated inflammatory signalling, may contribute in inducing a functional defect of the ECM network by post-translational mechanisms, which may trigger abdominal wall tissue loss and eventual rupture.	19397782
Communicable Diseases, Inflammation, Aneurysm	Altered Intercellular Communication	The serum copper/zinc ratio, a well-known marker of ongoing infection and/or inflammation, was higher (26%, p<0.001) in aneurysm patients.	19398057
Communicable Diseases, Inflammation	Altered Intercellular Communication	The results are compatible with active infection and/or inflammation, possibly initiated by C. pneumoniae.	19398057
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Several markers of systemic inflammation seem to play an active role in the pathophysiology of acute coronary syndrome and its evolution.	19398086
Meningism, Inflammation	Altered Intercellular Communication	The symptoms of the disease suddenly became aggravated and took a form of meningeal syndrome without inflammation of cerebrospinal fluid.	19399363
Inflammatory abnormality of the eye, Conjunctival scar	Altered Intercellular Communication	Later, he developed ocular inflammation with conjunctival scarring and synechiae formation as well as episodes of vesicles.	19399380
Necrotizing granulomatous inflammation, Calcinosis	Altered Intercellular Communication	All 13 pilomatrixomas demonstrated the characteristic histology with areas of basophilic islands, shadow cells, calcification and a chronic granulomatous inflammation with foreign body giant cells in varying amounts.	19399712
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	p120 (CagA) seropositivity was significantly more often present in patients with higher activity grade in the antrum (P = 0.025), p30 in patients with greater inflammation in the antrum (P = 0.025) and the corpus (P = 0.010), p33 in patients with greater inflammation in the corpus (P = 0.050), and p19 (OMP) in patients with lower intestinal metaplasia grades in the corpus (P = 0.025).	19399945
Airway structure	Altered Intercellular Communication	However, the role of OPN in eosinophilic airway inflammation is unclear.	19400906
Airway structure	Altered Intercellular Communication	To elucidate the role of OPN in eosinophilic airway inflammation.	19400906
Inflammation	Altered Intercellular Communication	There is growing evidence that inflammation plays an important role in atherogenesis.	19400931
Inflammation, Osteitis, Failure (biologic function)	Altered Intercellular Communication	The possibility of local osteitis can cause persistent mucosal inflammation and lead to failure of treatment.	19401044
Inflammation, Malignant neoplasm of endometrium	Altered Intercellular Communication	Chronic inflammation may play an etiologic role in endometrial cancer.	19401534
Inflammation	Altered Intercellular Communication	Laboratory investigations revealed systemic inflammation and lymphomonocytic pleocytosis of cerebrospinal fluid, supporting the diagnosis of Crohn's disease-associated vasculitis.	19402574
Inflammation, Ear Inflammation	Altered Intercellular Communication	Otitis media (OM) is an inflammation of the middle ear.	19402800
Inflammation, Uveitis	Altered Intercellular Communication	In uveitic eyes, active inflammation within 3 months before surgery increased the risk of CME when compared with eyes without inflammation (RR, 6.19; P = .04).	19403110
Inflammation, Thyroid carcinoma, Encapsulated Mass, Malignant Neoplasms	Altered Intercellular Communication	The authors suggest that these nonencapsulated lesions with no sign of inflammation may represent an early stage that may evolve to clinical cancers, contributing to the high incidence of clinically differentiated thyroid carcinomas observed in RN.	19403545
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Both oxidative stress and inflammation are known to play roles in the pathogenesis of cardiovascular disease.	19403985
Enterocolitis, Crohn Disease, Specimen Type - Fistula	Altered Intercellular Communication	An 18-year-old male experienced a first episode of Crohn's disease with inflammation of the colon, stenosis of small intestine and a fistula of the anal sphincter.	19404201
Inflammation, Hemorrhage	Altered Intercellular Communication	Diagnostic work-up - gastroscopy and colonoscopy 2004 and 2006, magnetic resonance enteroclysis 2004 and 2006 and wireless capsule enteroscopy 2006 - revealed slight inflammation in the ileum but no bleeding source.	19404201
Inflammation, Thrombosis	Altered Intercellular Communication	Thrombin-activated factor 2 receptor (F2R) links thrombosis to inflammation modulating interleukin (IL)6 synthesis.	19404549
Inflammation, Inflammatory disorder, Atherosclerosis	Altered Intercellular Communication	Interleukin-8 is a strong mediator of inflammation and has been implicated in the biochemical pathways involved in a wide range of inflammatory diseases including atherosclerosis.	19404719
Refractory anemias, Inflammation	Altered Intercellular Communication	The modest clinical efficacy plus the transient suppression of biomarkers of inflammation observed in this study suggest that p38 MAPK inhibition may not provide meaningful, sustained suppression of the chronic inflammation seen in RA.	19404957
Lymphocyte count increased, Inflammation, Eosinophilic disorder, Edema, Nasal Polyps	Altered Intercellular Communication	Although many proinflammatory cytokines have been identified in nasal polyp tissue, the initial trigger that causes this inflammation characterized by edema, lymphocytosis, and eosinophilia, is still unknown.	19405090
vascular inflammations	Altered Intercellular Communication	Statins can inhibit cell proliferation and vascular inflammation, which might help prevent AAA progression.	19406402
Inflammation, Atherosclerosis, Cerebrovascular accident	Altered Intercellular Communication	Inflammation plays an important role in atherosclerosis and stroke.	19407453
Bacterial Infections, Venous Stroke	Altered Intercellular Communication	LPS stimulation of PBMCs, a condition mimicking bacterial infection, induces differential expression of a group of cell-cell signaling genes in patients with previous atherothrombotic stroke.	19407453
Inflammation	Altered Intercellular Communication	Under inflammatory conditions, neutrophil apoptosis is delayed due to survival-factor exposure, a mechanism that prevents the resolution of inflammation.	19407828
Inflammation	Altered Intercellular Communication	Under inflammatory conditions, neutrophil apoptosis is delayed due to survival-factor exposure, a mechanism that prevents the resolution of inflammation.	19407828
Inflammation, Intraepithelial Neoplasia	Altered Intercellular Communication	Loss of cell polarity, a histological feature of gastric epithelial dysplasia, may be difficult to ascertain, especially in the setting of inflammation or injury.	19407852
Inflammation, Parietal, Visceral Pain, Structure of phrenic nerve	Altered Intercellular Communication	Whereas laparotomy results mostly in parietal pain, patients after laparoscopic cholecystectomy complain more of visceral pain results from the stretching of intraabdominal cavity, peritoneal inflammation and phrenic nerve irritation caused by residual carbon dioxide in the peritoneal cavity.	19408641
Inflammation	Altered Intercellular Communication	Moderate-to-severe gingival inflammation (modified SBI) was observed in 67.3% of the subjects.	19408821
Inflammation, Restenosis	Altered Intercellular Communication	Other factors such as macrophage-induced inflammation and reactive oxygen species accumulation may also contribute to restenosis.	19409002
Inflammation, Respiration Disorders, Endothelial dysfunction	Altered Intercellular Communication	Candidate genes for respiratory disease associated with markers of inflammation and endothelial dysfunction in elderly men.	19409562
Inflammation, Endothelial dysfunction, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation and endothelial dysfunction are important risk factors for cardiovascular disease (CVD).	19409562
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Endothelial dysfunction, Asthma	Altered Intercellular Communication	We hypothesized that candidate genes selected for a study of asthma and chronic obstructive pulmonary disorder (COPD) are associated with markers of systemic inflammation and endothelial dysfunction in an aging population.	19409562
ARCN1 gene, Inflammation, Cardiovascular Diseases, Endothelial dysfunction, Asthma	Altered Intercellular Communication	Our results suggest that genes thought to play a role in the pathogenesis of asthma and COPD may influence levels of serum markers of inflammation and endothelial dysfunction via novel SNP associations which have not previously been associated with cardiovascular disease.	19409562
Inflammation, Cardiovascular Diseases, Diabetes Mellitus	Altered Intercellular Communication	In patients with cardiovascular diseases several risk factors such as high blood pressure, diabetes, smoking and drinking habits, genetic disposition, and chronic inflammation must be considered.	19410072
Tracheitis, Subglottic stenosis	Altered Intercellular Communication	The study shows a successful symptomatic medical treatment of subglottic stenosis with resolution of tracheal inflammation and subglottic stenosis.	19410129
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	There is an association between inflammation and endothelial dysfunction.	19410250
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Systemic inflammation may be, at least in part, a cause and predictor of progression of endothelial dysfunction.	19410250
Vasculitis, Atherosclerosis	Altered Intercellular Communication	Angiotensin II is a vasoactive peptide involved in vessel inflammation during atherosclerosis, and angiotensin II receptor inhibitors are effective in preventing atherosclerosis.	19410957
Humor, Vitreous inflammatory cells	Altered Intercellular Communication	Visual acuity, anterior chamber and vitreous inflammation, optical coherence tomography findings, serial electro-oculograms (EOGs), microperimetry (MP-1) testing, flow cytometric analysis of cells derived from the aqueous humor, and aqueous humor cytokine profiles were evaluated.	19410956
Respiratory Distress Syndrome, Adult, Inflammation, Disease	Altered Intercellular Communication	C-reactive protein (CRP) has been studied as a marker of systemic inflammation and outcome in a number of diseases, but little is known about its characteristics in ARDS.	19411291
Inflammation	Altered Intercellular Communication	These data appear to be contrary to the established view that CRP is solely a marker of systemic inflammation.	19411291
Malignant Neoplasms	Altered Intercellular Communication	Differentially expressed genes were identified associated with malignancy, survival as well as hormonal activity providing a resource of candidate genes for an exploration of possible drug targets and diagnostic and prognostic markers.	19411298
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Defective efferocytosis in the airway may perpetuate inflammation in smokers with/without chronic obstructive pulmonary disease.	19411612
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	MATERIALS/SUBJECTS:We used lipopolysaccharide-activated cells from normal glucose tolerant (NGT) subjects and from Type 2 diabetes mellitus (T2DM) patients as T2DM is associated with chronic, low-grade inflammation, and measured immune mediator release with multiplex bead-based assays.	19411809
Diabetes Mellitus, Insulin-Dependent, Chronic inflammation, Myocarditis, CTCAE 5.0, MS gene	Altered Intercellular Communication	The latter are important murine pathogens that cause myocarditis, type 1 diabetes and chronic inflammation in the brains, mimicking multiple sclerosis.	19412527
Colon diverticulum anatomic structure	Altered Intercellular Communication	Chicken-bone perforation of a sigmoid colon diverticulum into the right groin and subsequent phlegmonous inflammation of the abdominal wall.	19412753
Perforation (observation)	Altered Intercellular Communication	We report an 82-year-old woman with perforation of a sigmoid diverticulum into the right groin with subsequent phlegmonous inflammation of the abdominal wall.	19412753
Inflammation	Altered Intercellular Communication	It is probably the result of acute inflammation in the subretinal space.	19412871
Inflammation	Altered Intercellular Communication	Interleukin-17A (IL-17A) and IL-17F play a role in tissue inflammation by inducing release of proinflammatory and neutrophil-mobilizing cytokines.	19414056
Inflammation, Atrophy of mucosa of stomach	Altered Intercellular Communication	In addition, IL-17A/-197A allele carriers had an increased risk of the development of gastric mucosal atrophy (OR, 1.68; 95% CI, 1.06-2.65; p = 0.026), and a positive relationship between the inflammation score and the number of -197A allele was observed (p = 0.022).	19414056
Communicable Diseases, Inflammation	Altered Intercellular Communication	The host is not able to clear the infection, leading to life-long chronic inflammation with continuous infiltration of lymphocytes and granulocytes.	19414551
Hernia of abdominal cavity, Pain Distress Question, Proteinuria, Toxic effect, Hypertension, CTCAE	Altered Intercellular Communication	Grade 3+ toxicities that occurred more often in the experimental arm versus control arm included hypertension (12% v 1.8%, respectively), wound complications (abdominal incisional hernia or infusion port dehiscence/inflammation; 1.7% v 0.3%, respectively), pain (11.1% v 6.3%, respectively), and proteinuria (2.7% v 0.8%, respectively).	19414665
Inflammation, Neoplasms, Neurosarcoidosis, Meningitis, Diabetes Mellitus, Vasculitis, CTCAE	Altered Intercellular Communication	Painful ophthalmoplegia is a rare pathologic condition caused by non-specific inflammation of the cavernous sinus, but other causes such as tumours, vasculitis, basal meningitis, neurosarcoidosis, diabetes can be responsible for the syndrome.	19415444
Gastritis	Altered Intercellular Communication	Heavy bacterial colonization (P = 0.008) and intense gastric inflammation (P < 0.0001) were associated significantly with severe clinical manifestations.	19416374
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Therefore, our results imply that depression may lead to inflammation and that inflammation may be one of the mechanisms through which depression contributes to cardiovascular risk.	19416750
Gingivitis	Altered Intercellular Communication	We emphasize that severe gingival inflammation, although infrequent, may represent an alteration specific to DC and therefore should be considered as an additional sign of this syndrome.	19419466
Inflammation, Periodontitis, Vascular Diseases	Altered Intercellular Communication	Periodontitis is ubiquitous and associated with serological evidence of exposure to periodontal organisms, systemic inflammation and vascular disease.	19419981
Presenile dementia, Inflammation, Diabetes Mellitus, Cerebrovascular accident	Altered Intercellular Communication	Dementia is a major public health problem likely related to a complex interaction between genetics and diseases associated with systemic inflammation, including diabetes, smoking and stroke.	19419981
Central nervous system demyelination, Inflammation, Demyelination, Axonal loss	Altered Intercellular Communication	Tissue was stained immunohistochemically and examined to determine: (i) the number of surviving corticospinal tract axons; (ii) the extent of grey and white matter demyelination; (iii) the degree of inflammation inside and outside of lesions; and (iv) the relationship between demyelination and axonal loss.	19420101
Bacteremia, Inflammation, Communicable Diseases	Altered Intercellular Communication	This report serves as a reminder that, although occurring rarely, inflammation overlying a cephalohematoma in an infant with bacteremia can indicate focal infection that requires incision and drainage for resolution.	19420180
Pain Distress Question, Neurogenic Inflammation, Chronic pain, Complex Regional Pain Syndromes	Altered Intercellular Communication	One dominant etiological hypothesis is that major mechanisms for CRPS symptoms, which might be present during the course of CRPS, are trauma-related cytokine release, exaggerated neurogenic inflammation, sympathetically maintained pain, and cortical reorganization in response to chronic pain.	19420958
Benign prostatic hypertrophy	Altered Intercellular Communication	The histological diagnosis was benign prostatic hyperplasia (BPH) or chronic inflammation.	19420972
Inflammation, Atherosclerosis	Altered Intercellular Communication	Measures of inflammation, such as hs-CRP, and indices of atherosclerosis, such as CCS, are likely to provide distinct information regarding cardiovascular risk.	19421644
Degenerative polyarthritis, Arthritis, Arthritis, Infectious	Altered Intercellular Communication	Synovial fluid cf-DNA/NETs values from patients with septic arthritis (3,286 +/- 386 ng/ml, n = 9) were significantly increased compared to patients with noninfectious joint inflammation (1,040 +/- 208 ng/ml, n = 17) or osteoarthritis (278 +/- 34 ng/ml, n = 16, p < 0.01).	19422041
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation has been shown to have a direct role in the initiation, maintenance, and recurrence of atrial fibrillation (AF) although the underlying mechanisms are unknown.	19422587
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Surprisingly, active cryptococcal infection with necrotizing granulomatous inflammation was demonstrated in the parathyroid, despite being on therapy.	19422668
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	One of the most current intriguing hypotheses on lung cancerogenesis envisages a role for inflammation as a possible trigger of both epithelial-mesenchymal transition and cancer development.	19423183
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Cigarette smoke has been suggested to be the main factor underlying the inflammation of the airways described in lung cancer patients.	19423183
Inflammation, Carcinoma of lung	Altered Intercellular Communication	We support the hypothesis that cigarette smoke be strongly connected to the inflammation of the airways observed in lung cancer patients.	19423183
Noninfiltrating Intraductal Carcinoma	Altered Intercellular Communication	Our results support the theory that comedo-type DCIS may share hormonal and reproductive risk factors with IBC, whereas the etiology of non-comedo DCIS deserves further investigation.	19423528
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Intragraft FOXP3 protein or mRNA during acute renal allograft rejection correlates with inflammation, fibrosis, and poor renal outcome.	19424039
Acute inflammation, Aortitis Syndrome	Altered Intercellular Communication	The diagnosis of aortitis syndrome was made due to protracted postoperative inflammation.	19425374
Inflammation, Convulsive Seizures, Depression, CTCAE, Somatoform Disorder	Altered Intercellular Communication	They may have the character of the inflammation of the peripherial nerves, convulsive seizures or take the form of the depression or the psychoorganic syndrome.	19425488
Inflammation	Altered Intercellular Communication	Chronic airflow obstruction and markers of systemic inflammation: results from the BOLD study in Iceland.	19427181
ARCN1 gene, Inflammation	Altered Intercellular Communication	Elevated circulating levels of C-reactive protein (CRP) and interleukin-6 (IL-6), both markers of systemic inflammation, have been found in COPD.	19427181
Inflammation	Altered Intercellular Communication	This finding underscores the possible importance of systemic inflammation in irreversible airflow limitation.	19427181
Inflammation, Heart failure, Metabolic Syndrome X	Altered Intercellular Communication	The roles of metabolic syndrome and chronic subclinical inflammation in arterial stiffening and the development of heart failure remain to be elucidated.	19427438
Arterial Stiffness, Inflammation, Ventricular Dysfunction, Metabolic Syndrome X	Altered Intercellular Communication	Because adiponectin, hs-CRP, ba-PWV, and NT-pro-BNP may represent markers for metabolic syndrome, chronic subclinical inflammation, arterial stiffness, and ventricular dysfunction, respectively, our results suggest that adiponectin may directly modulate both arterial stiffening and ventricular dysfunction.	19427438
Inflammation, Hyperglycemic Hyperosmolar Nonketotic Coma	Altered Intercellular Communication	Hemichorea-hemiballismus associated with nonketotic hyperglycemia: a possible role of inflammation.	19428031
Inflammation, Chorea, AMT gene	Altered Intercellular Communication	These results suggested that inflammation within the central nervous system may participate in the pathogenesis of chorea and ballismus induced by NKH.	19428031
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Converging lines of evidence support an association between systemic inflammation and depressive symptoms.	19428978
Refractory anemias, Rheumatoid Arthritis, Depression, CTCAE	Altered Intercellular Communication	Neuroimmune pathways may account for the high prevalence of depression in individuals with inflammatory conditions such as rheumatoid arthritis (RA).	19428978
Inflammation, Calcinosis	Altered Intercellular Communication	Serum levels of the calcification inhibitor fetuin-A are associated with the progression of AVC and MACE, independent of the renal function and inflammation.	19429630
Inflammation, Siderosis	Altered Intercellular Communication	The demonstration of CSF oligoclonal bands in the reported patient implies that inflammation might be involved in the pathogenesis of superficial siderosis.	19430272
Ischemia, Inflammation	Altered Intercellular Communication	We can speculate that the overexpression of VEGF induced by local ischemia and inflammation can make these patients more likely to have CNV.	19430731
Inflammation	Altered Intercellular Communication	11C-choline or 18F-labelled choline derivatives for visualizing the synthesis of phospholipids, are promising markers of plaque inflammation with potential advantages over 18F-FDG.	19430785
Edema, prostatitis	Altered Intercellular Communication	This accounts for its ability to reduce edema in prostatic inflammation.	19432231
Inflammation, Polyp of urethra, Traumatic injury	Altered Intercellular Communication	Factors of a higher risk of acquired urethral polyps are secondary trauma of urethral mucosa in device investigations and manipulations as well as chronic inflammation.	19432235
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	We further demonstrate that the association of Hb, Hp, and Hx proteins with HDL positively correlates with inflammatory properties of HDL and systemic inflammation in CHD patients.	19433579
Inflammation	Altered Intercellular Communication	Motor involvement is probably due to the spreading of inflammation from the dorsal root ganglia to the ventral roots and may be more extensive than the affected dermatomes.	19434442
Corneal edema	Altered Intercellular Communication	The eye had mild corneal edema with anterior chamber inflammation.	19435962
Inflammation, Dental Plaque	Altered Intercellular Communication	This result suggests that inflammation simultaneously contributes to both plaque growth and plaque instability.	19436122
Inflammation, Carcinogenesis	Altered Intercellular Communication	Growing evidence points to a role for inflammation in prostate carcinogenesis.	19436291
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Assessment of airway inflammation in the clinical course of acute exacerbations of chronic obstructive pulmonary disease (AECOPD) may advance our understanding of the pathogenesis and treatment.	19436689
Airway structure	Altered Intercellular Communication	To assess airway inflammation in patients during the course of AECOPD by serial analyses of their exhaled breath condensates (EBC).	19436689
ARCN1 gene, Inflammation	Altered Intercellular Communication	Change in inflammation in out-patient COPD patients from stable phase to a subsequent exacerbation.	19436694
ARCN1 gene	Altered Intercellular Communication	Inflammation increases during exacerbations of COPD, but only a few studies systematically assessed these changes.	19436694
Tumor necrosis, Inflammation, Bacterial Infections, Exacerbation	Altered Intercellular Communication	These exacerbations had significantly increased sputum total cell and neutrophil counts, leukotriene-B4, myeloperoxidase, interleukin-8 and interleukin-6, and tumor necrosis factor-alpha (TNF-alpha) levels, and were also associated with more systemic inflammation compared to exacerbations without a bacterial infection.	19436694
Inflammation, Bacterial Infections, Exacerbation	Altered Intercellular Communication	The increase in systemic inflammation during exacerbations seems to be limited to exacerbations caused by bacterial infections of the lower airways.	19436694
Inflammation, Erythema, Pyoderma Gangrenosum, Ulcer	Altered Intercellular Communication	In addition, there were ulcerative lesions surrounded by cutaneous inflammation and erythema on her extremities, indicative of pyoderma gangrenosum.	19437575
Inflammation, Sarcopenia	Altered Intercellular Communication	Inflammation in patients defined as frail by Fried's phenotypic definition may be related to sarcopenia.	19438806
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP), a marker of inflammation, has been associated with cardiovascular disease.	19438929
Inflammation, Cardiovascular Diseases, Coronary heart disease	Altered Intercellular Communication	Given the high risk of cardiovascular disease in South Asians and the importance of inflammation in coronary heart disease we tested the hypothesis that circulating C-reactive protein (CRP) and interleukin 6 (IL-6) would be higher in healthy British born infants of South Asian origin than in infants of European origin in the first 2 years of life.	19439300
Inflammation	Altered Intercellular Communication	In our cohort, South Asian origin infants had significantly lower markers of inflammation compared with European infants.	19439300
Airway structure	Altered Intercellular Communication	Induced sputum analysis has been widely used to assay airway inflammation.	19439918
Inflammation, Uterine Fibroids, Granulomatous, Vasculitis, CTCAE, Endometrial Carcinoma	Altered Intercellular Communication	Nongranulomatous inflammation occurred in most patients with IGynV, while the predominant histologic pattern noted in SGynV was granulomatous.While vasculitis was the only lesion in 32% of the resected specimens, leiomyomas (18.4%) and endometrial carcinoma (8.3%) were the most frequent concomitant benign and malignant (nonvasculitic) lesions, respectively.	19440120
Inflammation, Bacterial Infections, Malignant Neoplasms	Altered Intercellular Communication	These findings, taken together, suggest a link between bacterial infection, inflammation and amyloid deposition of pro-inflammatory proteins S100A8/A9 in the prostate gland, such that a self-perpetuating cycle can be triggered and may increase the risk of malignancy in the ageing prostate.	19440546
Pancreatitis, Acute, Communicable Diseases, Inflammation	Altered Intercellular Communication	Triggering receptor expressed on myeloid cells-1 expression on monocytes is associated with inflammation but not with infection in acute pancreatitis.	19442309
Inflammation	Altered Intercellular Communication	In AP, local inflammation is followed first by the systemic inflammatory response syndrome and then by the compensatory anti-inflammatory response syndrome, which is defined by low human leukocyte antigen (HLA)-DR expression on monocytes, increased concentration of the anti-inflammatory cytokine IL-10, and decreased monocyte function.	19442309
Communicable Diseases, Inflammation	Altered Intercellular Communication	Increased TREM-1 expression was associated with the presence of inflammation but not infection in AP.	19442309
Inflammation, Spondylitis	Altered Intercellular Communication	Ankylosing spondylitis (AS) is characterized by inflammation of the entheses and paravertebral structures, leading in time to bone formation at those sites.	19442629
Inflammation, Prediabetes syndrome	Altered Intercellular Communication	Community-based population data indicates the significant alterations of insulin resistance, chronic inflammation and urine ACR in IFG combined IGT group among prediabetic population.	19442860
Inflammation, Prediabetes syndrome, Endothelial dysfunction	Altered Intercellular Communication	IR, chronic inflammation and endothelial dysfunction dose exist in prediabetic individuals, especially in IFG+IGT population.	19442860
Inflammation	Altered Intercellular Communication	Gutt's index and ACR might seem to be more sensitive than adiponectin and HOMA-IR index as IR and chronic inflammation maker in prediabetic population.	19442860
Inflammation	Altered Intercellular Communication	Inflammation plays a key role in the development of AMI.	19442944
Inflammation, Carotid Stenosis, Giant Cell Arteritis, Arteritis, Acute myocardial infarction, Takayasu Arteritis	Altered Intercellular Communication	CE-CMR of the vessel wall has been found useful for the characterization of inflammatory tissue signal changes in patients with carotid artery stenosis, giant cell arteritis, or Takayasu's arteritis; however, it has never been serially performed in the coronary artery wall in patients with acute and chronic myocardial infarction using a gadolinium-based contrast medium and compared with systemic markers of inflammation.	19442944
Inflammation, Edema	Altered Intercellular Communication	This technique may be useful for the characterization of transient coronary tissue signal changes, which may represent edema or inflammation during the post-infarction phase.	19442944
Inflammation, Hemoperitoneum	Altered Intercellular Communication	Pathologically it was possible that the local inflammation (epicarditis) due to the deposition of amyloid in the epicardium and perivascular tissue caused the bloody effusion.	19443978
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Markers of endothelial dysfunction and inflammation were also evaluated.	19444092
Inflammation, Immune-mediated	Altered Intercellular Communication	These findings demonstrate altered T-cell subsets in patients with immune-mediated disease, particularly at sites of inflammation.	19444449
Inflammation	Altered Intercellular Communication	It also plays a role in inflammation and oxidative stress.	19446293
Inflammation, Systolic dysfunction, Atherosclerosis	Altered Intercellular Communication	Left ventricular (LV) systolic dysfunction is common in patients with atherosclerosis, and both inflammation and oxidative stress have also been implicated in its development and progression.	19446293
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Ultrasonographic evidence of inflammation is frequent in hands of patients with erosive osteoarthritis.	19447214
Nonalcoholic Steatohepatitis, Inflammation, Liver carcinoma, Fatty Liver, Non-alcoholic Fatty Liver Disease, Liver Cirrhosis, Fatty Liver Disease	Altered Intercellular Communication	Nonalcoholic steatohepatitis (NASH) represents a subset of nonalcoholic fatty liver disease manifested by hepatic fatty infiltration and inflammation which may progress to cirrhosis and its subsequent complications, to include hepatocellular carcinoma.	19448566
Refractory anemias, Inflammation, Arthritis	Altered Intercellular Communication	Infliximab therapy was started 3 years and 8 months after TKAs as a result of multiple arthritides showing high inflammation of RA.	19449010
Inflammation, Atherosclerosis, Refractory anemias, Rheumatoid Arthritis, atherosclerotic	Altered Intercellular Communication	Although inflammation has a defined role in the pathogenesis of atherosclerosis, the link between rheumatoid arthritis (RA) parameters of disease activity and atherosclerotic findings are not defined.	19449480
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Recently, inflammation has been considered as a risk factor of postoperative atrial fibrillation (PAF).	19450160
Inflammation, Toxic effect	Altered Intercellular Communication	Recent data suggest that systemic inflammation results in reduced hepatic drug metabolism and increased toxicity from chemotherapy.	19450285
Inflammation, Albinism, Ulcer	Altered Intercellular Communication	Immunosuppression (KS), chronic ulcer, inflammation, albinism, and solar radiation were identified risk factors.	19450404
Inflammation, Septic Shock	Altered Intercellular Communication	Given the harmful effects of NO excess in septic shock, ADMA levels may be increased as a counter-system against inflammation and oxidative stress in this life-threatening disorder.	19450686
Inflammation, Osteonecrosis of Jaw, Necrosis	Altered Intercellular Communication	Three main histological patterns were identified in ONJ patients: 1 - Areas with active acute inflammation, characterized by predominance of soft tissues, inflammatory infiltrate, acellular necrotic debris, thin-walled and dilated blood vessel, intensely basophilic bone spiculae with scalloped borders showing prominent bone resorption.	19450715
Inflammation	Altered Intercellular Communication	Varying degrees of inflammation in the protein localization of TIMP-3 and TIMP-4 were found.	19450793
Inflammation	Altered Intercellular Communication	TIMP-4 immunoreactivity (IR) was weak in the endothelial cells, fibroblasts, epithelial basal and parabasal cells while the degree of inflammation differed as well.	19450793
X-linked inheritance, Inflammation, Doctor of Dental Medicine, Degenerative disorder, Muscular Dystrophy, Duchenne	Altered Intercellular Communication	Duchenne muscular dystrophy (DMD) is an X-linked, degenerative muscle disease that is exacerbated by secondary inflammation.	19451692
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	These studies suggest that OPN may be a promising therapeutic target for reducing inflammation and fibrosis in individuals with DMD.	19451692
Disability, Inflammation, Rheumatism	Altered Intercellular Communication	Mud-bath treatment has a relevant therapeutic activity in reducing symptoms and disabilities in rheumatic diseases, as studies on inflammation process and clinical symptomatology have shown.	19452099
Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	Tumor markers and rectal cancer: support for an inflammation-related pathway.	19452524
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Inflammation may be a key element in the etiology of colorectal cancer.	19452524
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	In our study, we examine associations between factors related to inflammation and specific rectal cancer mutations.	19452524
Neoplasms	Altered Intercellular Communication	These results suggest that inflammation-related factors may have unique associations with various rectal tumor markers.	19452524
Ulcer, Inflammation, Pain Distress Question	Altered Intercellular Communication	At follow-up gastroscopy, no ulcers, inflammation, break in the mucosa, or pain was noted.	19453029
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Symptoms of inflammation dominating in the clinical picture do not exclude the possibility of malignancy.	19453090
Inflammation, Diverticular Diseases, chronic diverticulitis	Altered Intercellular Communication	Patients with symptomatic diverticular disease exhibit increased neuropeptides in mucosal biopsies which may reflect resolved prior inflammation, as it parallels the changes seen in acute and chronic diverticulitis.	19453515
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	It is possible that this mechanism might contribute to induce tissue regeneration and down-regulation of inflammation in OA.	19453649
Tolosa-Hunt Syndrome, Inflammation, Methylated spirit	Altered Intercellular Communication	Tolosa-Hunt syndrome (THS) is a very rare, relapsing, and remitting painful ophthalmoplegia caused by nonspecific granulomatous inflammation in the cavernous sinus.	19453827
Granulomatous inflammation	Altered Intercellular Communication	Brain MRI showed granulomatous inflammation in both cavernous sinuses and thickening of the surrounding dura mater of the cranial base, suggesting the coexistence of focal hypertrophic cranial pachymeningitis.	19453827
Inflammation	Altered Intercellular Communication	There might be a positive regulatory loop between NF-kappaB and TNF-alpha, which may contribute to inflammation in OLP; NF-kappaB may also protect epithelial keratinocytes from excessive apoptosis.	19453840
Inflammation	Altered Intercellular Communication	Immunoregulatory cytokines are more important for suppression of inflammation in asymptomatic lesions and in this context the effect of TGF-beta is more potent and different from IL-10.	19453841
Hematuria, CTCAE, Malignant Neoplasms	Altered Intercellular Communication	Urethral amyloidosis is a rare, probably inflammatory condition usually presenting with hematuria and obstructive urinary symptoms, thus mimicking urethral malignancy.	19453902
Inflammation, Adult onset, Myositis, CTCAE 5.0, Myositis	Altered Intercellular Communication	Sporadic inclusion-body myositis (sIBM) is the most common disabling, adult-onset, inflammatory myopathy histologically characterized by intense inflammation and vacuolar degeneration.	19454532
Inflammation, Primary malignant neoplasm, Neoplasm Metastasis	Altered Intercellular Communication	Matrix metalloproteinase-2 (MMP-2) is a well-known mediator of cancer metastasis but is also thought to be involved in several aspects of cancer development, including cell growth and inflammation.	19454611
Pneumonitis	Altered Intercellular Communication	In addition, loss of CD27 on BAL CD4(+) T cells inversely correlates with markers of lung inflammation.	19454729
Orbital Pseudotumor	Altered Intercellular Communication	Unilateral orbital inflammation in a child after a jellyfish sting to the lower extremities.	19454944
Orbital Pseudotumor	Altered Intercellular Communication	After 5 asymptomatic weeks, she developed unilateral orbital inflammation that did not respond to systemic antibiotics, antihistamines, or steroids.	19454944
Inflammation, Atherosclerosis	Altered Intercellular Communication	There is increasing evidence that adventitial inflammation may participate in atherosclerosis development.	19455698
Inflammation, Chronic infectious disease	Altered Intercellular Communication	It is possible that inflammation and some chronic infections, such as those induced by C. pneumoniae, could have a marked influence on adventitial cell proliferation.	19455698
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The interleukin-6 (IL-6) pathway is one of the mechanisms that link inflammation and angiogenesis to malignancy.	19457231
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Because the C-reactive protein (CRP) is a representative marker for inflammation, CRP has recently been associated with the progression of disease in many cancer types.	19457231
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Th17 cells are CD4+ cells that produce interleukin 17 (IL-17) and are potent inducers of tissue inflammation and autoimmunity.	19457253
Inflammation, Thrombosis, Atherosclerosis	Altered Intercellular Communication	Chronic inflammation has also been associated with atherosclerosis and thrombosis.	19458634
Fibrinoid necrotizing inflammation	Altered Intercellular Communication	Serum MCP-1 levels were significantly correlated with the disease activity scores of 28 joints combined with CRP (DAS28-CRP), indicating the role of MCP-1 in the pathogenesis of rheumatoid inflammation.	19458908
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Glycaemic status in relation to oxidative stress and inflammation in well-controlled type 2 diabetes subjects.	19459227
Inflammation, Obesity, Abdominal	Altered Intercellular Communication	Furthermore, inflammation was more related to abdominal obesity than to glycaemic control.	19459227
ARCN1 gene, Inflammation	Altered Intercellular Communication	Relationships between inflammation severity and small intestinal absorption of fats, protein, carbohydrates in patients with moderate and severe COPD means loss of essential nutrients, primarily protein and fats.	19459416
Inflammation	Altered Intercellular Communication	Despite an associated increase in systemic inflammation, G-CSF treatment does not lead to acute impairment of brachial artery endothelial function in either healthy subjects or patients with MI.	19460770
Inflammation, Ischemia	Altered Intercellular Communication	No evidence of inflammation or ischaemia was observed during G-CSF mobilisation and PBSC collection.	19460773
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation has been identified as a marker for cardiovascular disease.	19461006
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Epidemiological evidence suggests a relationship between chronic inflammation and lung cancer.	19461122
Inflammation	Altered Intercellular Communication	Inflammation in the lung may be modulated by host genetic factors such as polymorphisms in inflammatory genes.	19461122
Gastrointestinal inflammation, Neoplasms	Altered Intercellular Communication	More recently, the dimeric isoform of M2-pyruvate kinase (tumor M2-PK) has been suggested as a marker of gastrointestinal inflammation.	19462434
Inflammation	Altered Intercellular Communication	Meningoencephalitis of this case was thought to be caused by RP-associated perivascular inflammation.	19462815
Inflammation, Swelling	Altered Intercellular Communication	Blood test showed severe inflammation and computed tomographic (CT) scan demonstrated swelling and irregular enhancement of the right kidney.	19462829
Inflammation, Platelet aggregation test result	Altered Intercellular Communication	Additionally, there were strong correlations between platelet aggregation and flow cytometric measurements (p < or = 0.04) and between specific inflammation markers (p < or = 0.02).	19463513
Inflammation, Dyslipidemias, Hypertension, CTCAE, Obesity	Altered Intercellular Communication	T2DM is associated with obesity, hypertension, dyslipidemia, hypothalamic pituitary adrenocortical (HPA) axis abnormalities and inflammation, all of which have been shown to negatively impact the brain.	19463794
Prostatic fluid, Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Evaluation of interleukin-8 in expressed prostatic secretion as a reliable biomarker of inflammation in benign prostatic hyperplasia.	19464042
Inflammation, Prostatic fluid, Elastosis perforans serpiginosa	Altered Intercellular Communication	To provide objective parameters of inflammation, this prospective study quantified the IL-8 in expressed prostatic secretion (EPS) from BPH patients with or without histologic inflammation.	19464042
Migraine Disorders, Neurogenic Inflammation	Altered Intercellular Communication	Calcitonin gene-related peptide (CGRP) is a potent vasodilator and supposed to be responsible for neurogenic inflammation involved in migraine.	19464067
Hepatitis, Inflammatory disorder	Altered Intercellular Communication	Its role in inflammatory diseases of other organs is controversial and poorly investigated regarding liver inflammation, although the organ is innervated by CGRP containing primary sensory nerve fibers.	19464067
Necrotizing granulomatous inflammation	Altered Intercellular Communication	FNB confirmed the results for malignant PVT in four of five patients, for benign granulomatous inflammation PVT in one of five patients in which CEUS showed early arterial enhancement of the PVT.	19464131
Necrotizing granulomatous inflammation, Intrahepatic bile duct	Altered Intercellular Communication	In one patient with intrahepatic bile duct stone, CEUS were positive for malignant PVT, whereas FNB was negative (benign granulomatous inflammation PVT); follow-up examination confirmed benign PVT.	19464131
Chronic inflammation, Thoracic esophagus, Malignant Neoplasms	Altered Intercellular Communication	D2-40 immunohistochemical staining for human lymphatic epithelium was performed at three sites in the cervical and thoracic esophagus in 16 donated cadavers without macroscopic malignancy or chronic inflammation.	19464457
Inflammation	Altered Intercellular Communication	To our knowledge, this is the first report of CK after LASIK that required surgical intervention for interface inflammation.	19465304
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Several studies suggest that inhaled and oral corticosteroids repress systemic inflammation in chronic obstructive pulmonary disease (COPD).	19465442
Inflammation, Familial Mediterranean Fever, Fever, CTCAE, Brucellosis	Altered Intercellular Communication	Familial Mediterranean fever (FMF) is hereditary episodic febrile syndrome characterized by acute attacks of fever and serosal inflammation, generally lasting 1-3 days and resolves spontaneously.	19466424
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The chronic systemic inflammation and oxidative stress are important features in chronic obstructive pulmonary disease (COPD).	19466515
Inflammation, atherosclerotic	Altered Intercellular Communication	Both local and systemic inflammation and oxidative stress negatively affect the atherosclerotic process.	19466515
ARCN1 gene, Inflammation	Altered Intercellular Communication	Metabolic alterations, systemic inflammation, and neurohormonal activation frequently occur in patients with COPD.	19466515
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Nitric oxide (NO) is a major mediator of joint tissue inflammation and damage in osteoarthritis (OA) and mediates the nitration of tyrosine (Y*) residues in proteins.	19467351
Inflammation, Gastric Squamous Cell Carcinoma, Leukocytosis, Squamous cell carcinoma	Altered Intercellular Communication	This case suggests that gastric squamous cell carcinoma likely arises in the setting of long-standing, chronic inflammation, and like squamous cell carcinoma in other organ systems, may be associated with paraneoplastic leukocytosis.	19467693
Inflammation	Altered Intercellular Communication	Adiponectin, leptin, markers of inflammation, apolipoproteins (apo) AI and B, and lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) were measured.	19468010
Fibrosis Assessment, Stiff Skin Syndrome	Altered Intercellular Communication	Stiff skin syndrome: evidence for an inflammation-independent fibrosis?	19468049
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The data suggest that fibrosis in SSS might be independent from inflammation.	19468049
Inflammation	Altered Intercellular Communication	Evaluation encompassed endosopic signs of inflammation, its spread, and severity.	19469256
Inflammation, Skin carcinoma	Altered Intercellular Communication	Dense inflammation can obscure nonmelanoma skin cancer (NMSC) on frozen sections, prompting removal of additional layers to ensure negative margins.	19469800
Inflammation	Altered Intercellular Communication	Our objective was to develop an effective ultrarapid CK frozen section immunostain to be used during MMS in cases of NMSC with dense or perineural inflammation.	19469800
Inflammation	Altered Intercellular Communication	It is hopeful that this technique may prevent recurrences after MMS and limit the number of Mohs layers required to obtain free margins when inflammation is abundant.	19469800
Inflammation, Data types - Address	Altered Intercellular Communication	The skin of AD patients is usually colonized by Staphylococcus aureus (S. aureus); its exotoxins may trigger or enhance the cutaneous inflammation.	19469892
Data types - Address, Dermatitis	Altered Intercellular Communication	Several mediators are related to the AD immune imbalance and interleukin-18 (IL-18), an inflammatory cytokine, may play a role in the atopic skin inflammation.	19469892
Data types - Address, Dermatitis	Altered Intercellular Communication	IL-18 secretion from AD upon stimulation was similar from controls, which may indicate a diverse mechanism of skin inflammation maintained by Staphylococcus aureus.	19469892
Immune System Diseases, Data types - Address, Dermatitis	Altered Intercellular Communication	On the other hand, augmented IL-18 secretion from AD sera and non-stimulated cell culture may enhance the immune dysfunction observed in AD, leading to constant skin inflammation.	19469892
Inflammation, FAM126A gene	Altered Intercellular Communication	Our study suggests that control of inflammation might be critical for improving treatment outcome in advanced HCC.	19470923
Steatohepatitis, Hepatic inflammation, Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Hepatic inflammation secondary to liver steatosis is a potential contributor to the low-grade inflammation associated with the metabolic syndrome.	19472103
Inflammation, prostatitis	Altered Intercellular Communication	The expression of ERbeta is reduced with increased scores on the inflammation of the prostate tissues in BPH patients, and the decreased ERbeta expression may be associated with the inflammatory stimulation of prostatitis.	19472903
Refractory anemias, Inflammation, Rheumatoid Arthritis, Atherosclerosis	Altered Intercellular Communication	Chronic systemic inflammation is of major importance in the development of atherosclerosis in rheumatoid arthritis (RA).	19473561
Inflammation, Inflammatory disorder, Rheumatism	Altered Intercellular Communication	Development of a simple and accurate technique for detecting active inflammation in the joints and other tissues of patients with inflammatory disorders is an unmet need in rheumatic diseases.	19473565
Refractory anemias, Degenerative polyarthritis, Arthropathy	Altered Intercellular Communication	In this open-label, cross-sectional study, a total of 40 patients with RA (26 with one or more swollen joints, 14 with clinically quiescent joint disease; 0/66 joint count) as well as 6 patients with osteoarthritis, 12 patients with other inflammatory conditions and 5 healthy subjects received 0.1 mg of EC20 labeled with 20-25mCi of technetium-99m.	19473565
Disease, Inflammation, Inflammatory disorder, Brucellosis	Altered Intercellular Communication	During the last decade, the increasing knowledge on the pathogenic mechanisms related to a number of diseases associated to mutations of genes associated to autoinflammatory diseases had a terrific impact on the understanding of pivotal mechanisms regulating the inflammatory response and therefore represents one of the major advance in the field of inflammation.The International Congress on Familiar Mediterranean Fever and Systemic Autoinflammatory Diseases brings together the experts in the field every two and a half years and represents a unique opportunity for an update on the recent progress in this growing field.	19473583
Tissue damage, Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Inflammation has been described as a risk factor for PCa and depends on the production of cytokines in response to tissue damage or the presence of stimuli that induces cellular stress.	19474090
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Accumulating epidemiological and molecular evidence suggests that inflammation is an important component in the etiology of PCa.	19475570
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Furthermore, a high degree of adherence to MD has been found related to lower concentrations of inflammation, endothelial dysfunction and coagulation markers.	19475839
Inflammation, Nasal Polyps, MS4A2 wt Allele, Allergic	Altered Intercellular Communication	Clinical patterns, a history of atopy, environmental exposure, eosinophil-mediated inflammation, the presence of inflammatory mediators, and sensitization to some allergens indicate that nasal polyposis is associated with allergic phenomena.	19476014
Inflammation	Altered Intercellular Communication	Ageing of HIV+ patients, insufficient penetration of anti-viral drugs into the brain with continuous low-grade viral production and inflammation may play a role.	19476058
Inflammation, Calcification of coronary artery	Altered Intercellular Communication	Favorable cardiovascular risk factor profile is associated with reduced prevalence of coronary artery calcification and inflammation in asymptomatic nondiabetic white men.	19476570
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	However, the relationship of the absence of CVRFs with subclinical CVD and inflammation is not well described.	19476570
Inflammation, Atherosclerosis	Altered Intercellular Communication	Our study supports the notion that a favorable CVD profile is associated with less underlying atherosclerosis and inflammation and further highlights the importance of primary prevention of CVRFs.	19476570
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Osteopontin (OPN) is an important mediator of inflammation and cancer progression.	19476604
Inflammation	Altered Intercellular Communication	Preliminary studies indicate that USPIO-enhanced MRI can identify macrophage infiltration in human carotid atheroma in vivo and hence may be a surrogate marker of plaque inflammation.	19477353
Fibrosis Assessment, Interstitial inflammation, Bronchiolitis Obliterans	Altered Intercellular Communication	In the chemotherapy group, patterns of interstitial involvement were variable interstitial inflammation and fibrosis associated with obliterative bronchiolitis [Roberts JR, Eustis C, Devore R, et al.	19477548
Inflammation, Iridocyclitis, Retinal thickening	Altered Intercellular Communication	To determine the frequency of retinal thickening (RT) in eyes with iridocyclitis and to examine the correlations among anterior chamber (AC) inflammation, RT, and visual acuity.	19477710
Inflammation	Altered Intercellular Communication	Fast peritoneal membrane transport status may be due to inflammation or increased peritoneal membrane surface area.	19478100
Inflammation, hepcidin	Altered Intercellular Communication	Furthermore, the elevated levels of hepcidin-25 and hepcidin-20 were not correlated with the serum levels of markers for inflammation, interleukin-6 and C-reactive protein, in the patients with AMI.	19478464
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease, neutrophilic	Altered Intercellular Communication	Airway inflammation in chronic obstructive pulmonary disease (COPD) is predominately neutrophilic, but some subjects demonstrate eosinophilic airway inflammation.	19478474
Appendicitis, CTCAE	Altered Intercellular Communication	Our criteria can improve sensitivity in comparison with conventional major criteria because our criteria enabled us to differentiate appendicitis without periappendiceal inflammation from a normal appendix.	19478631
Inflammation, Gall Bladder Diseases	Altered Intercellular Communication	Transient arterial enhancement in patients with suspected biliary disease is well correlated with clinical parameters suggestive of inflammation.	19478633
Crohn Disease	Altered Intercellular Communication	Crohn's disease (CD) is a chronic granulomatous inflammation of the intestine.	19479064
Inflammation	Altered Intercellular Communication	The presence of MAP reactive T cells with a Th1 or Th1/Th17 phenotype may suggest a possible role of mycobacteria in the inflammation seen in CD.	19479064
Inflammation, Necrosis, Lupus Erythematosus	Altered Intercellular Communication	Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus.	19479824
Autoimmune Diseases, Inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Autoantibody-mediated phagocytosis of SNEC is accompanied by secretion of inflammatory cytokines, fueling the inflammation that contributes to the perpetuation of autoimmunity in SLE.	19479824
Airway structure, ARCN1 gene	Altered Intercellular Communication	Airway inflammation in COPD can be measured using biomarkers such as induced sputum and Fe(NO).	19480658
ARCN1 gene, Inflammation	Altered Intercellular Communication	This study set out to explore the heterogeneity of COPD using biomarkers of airway and systemic inflammation and pulmonary function by principal components analysis (PCA).	19480658
Airway structure, Inflammation	Altered Intercellular Communication	Unrelated components of disease were identified, including neutrophilic airway inflammation which was associated with systemic inflammation, and sputum eosinophils which were related to increased Fe(NO).	19480658
Airway structure	Altered Intercellular Communication	We confirm dissociation between airway inflammation and lung function in this cohort of patients.	19480658
Inflammation, Sarcoidosis, Granulomatous	Altered Intercellular Communication	Activated T helper (Th)-1 pulmonary CD4+ cells and their mediators are essential for the inflammation and granulomatous process in sarcoidosis.	19480659
Inflammation, Asthma, Kit Ligand, human	Altered Intercellular Communication	Serum levels of SCF and its soluble receptor c-kit seem to be reflect asthma severity suggesting a role for these molecules in asthmatic inflammation.	19480722
Inflammation, Dental Plaque	Altered Intercellular Communication	Inflammation is important in plaque vulnerability but the role of atheroprotective mediators in unstable plaques is not defined.	19481824
vascular inflammations	Altered Intercellular Communication	The apolipoproteinA-I (apoA-I) component of HDL, and CD4+/CD25+ regulatory T cells (with their major transcription factor, Foxp3), have been implicated in the suppression of vascular inflammation.	19481824
Inflammation	Altered Intercellular Communication	These data suggest ineffective/insufficient protection against atherosclerosis-mediated inflammation by these "atheroprotective" moieties.	19481824
Inflammation	Altered Intercellular Communication	These findings support the fact that abnormal MRI findings in the spinal cord may be reflective of active inflammation in the early stages of rapidly progressive HAM.	19481863
Inflammation, Traumatic injury	Altered Intercellular Communication	In this study, the change of p38 MAPK signaling pathway in trauma patient with different severity and its clinical significance in trauma inflammation were investigated.	19482318
Airway structure, Pyoderma Gangrenosum	Altered Intercellular Communication	Although the etiology of pyoderma gangrenosum is poorly understood, this case suggests that a common pathogenesis may account for the simultaneous cutaneous and airway inflammation.	19483173
Inflammation, Traumatic injury	Altered Intercellular Communication	The presence of cervical fat seems to be unrelated to patient age, parity, parametrial adipose tissue, inflammation, or prior trauma.	19483621
Inflammation, Waldenstrom Macroglobulinemia, Chronic osteomyelitis, Necrosis	Altered Intercellular Communication	Initially, 13 of 66 (19.7%) cases were read by a surgical pathologist as chronic inflammation, with 6 having features suggestive of chronic osteomyelitis, including polyclonal plasma cells, necrosis, and lymphoplasmacytic infiltrate.	19483668
Inflammation, Chronic osteomyelitis	Altered Intercellular Communication	Six of 13 (46%), were read as containing fragmented bony spicules, fibrotic and fatty marrow, lymphoplasmacytic inflammation, and aggregates of mature, polyclonal plasma cells, suggesting the possibility of chronic osteomyelitis.	19483668
Hyperglycemia, Inflammation	Altered Intercellular Communication	Hyperglycemia is associated with greater prevalence of prefrail and frail status; BMI, inflammation, and comorbidities do not explain the association.	19484839
Impatent structure, Communicable Diseases, Hydrocephalus, Neoplasms	Altered Intercellular Communication	Causes of unilateral hydrocephalus resulting from an obstruction at the Monro foramen include foraminal atresia, tumors, gliosis, contralateral shunting, and infectious and inflammatory conditions.	19485736
allergic inflammation	Altered Intercellular Communication	The pulmonary artery supplies the distal parts of the lungs and likely represents a site of immunological reaction in allergic inflammation.	19486035
Asthma	Altered Intercellular Communication	The objective of this study was to describe the inflammatory cell phenotype of pulmonary artery adventitial inflammation in lung tissue from patients who died of asthma.	19486035
Neoplasms	Altered Intercellular Communication	MF classically presents as patches, plaques and tumours as originally described by Alibert and Bazin, but many other clinical presentations may occur, often mimicking other inflammatory conditions.	19486059
Inflammation	Altered Intercellular Communication	Decreased CD3+CD16+ natural killer-like T-cell percentage and zeta-chain expression accompany chronic inflammation in haemodialysis patients.	19486472
HD Term Type, Inflammation	Altered Intercellular Communication	All the evaluated markers of inflammation were increased in HD patients.	19486472
Inflammation	Altered Intercellular Communication	Measures towards alleviating chronic inflammation could partially restore NKL T-cell impairment.	19486472
Inflammation	Altered Intercellular Communication	Persistent depressive symptomatology and inflammation: to what extent do health behaviours and weight control mediate this relationship?	19486658
Inflammation, Bipolar Disorder	Altered Intercellular Communication	In summary, the association between depressive symptoms and low grade inflammation can be partly explained by behavioural risk factors.	19486658
Inflammation, Depression, CTCAE	Altered Intercellular Communication	The presence of persistent depression appears to be associated with the greatest risk of elevated inflammation.	19486658
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays an important role in the initiation and progression of atherosclerosis but the contribution of neutrophils to this process is unclear.	19486978
Tumor necrosis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Moreover, from both the pathogenetic and therapeutic point of view, new relevant information is highlighted regarding the possible role of tumour necrosis factor alpha (TNF-alpha) in mucosal inflammation.	19487168
Granuloma, Inflammation	Altered Intercellular Communication	Histology revealed well-formed granulomas and markedly diminished inflammation.	19487479
Respiratory Distress Syndrome, Adult, Inflammation	Altered Intercellular Communication	Lungs of patients with acute respiratory distress syndrome show diffuse inflammation in normally aerated regions: a [18F]-fluoro-2-deoxy-D-glucose PET/CT study.	19487931
Respiratory Distress Syndrome, Adult, Acute Lung Injury, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	Neutrophilic inflammation plays a key role in the pathogenesis of acute respiratory distress syndrome (ARDS) and acute lung injury (ALI).	19487931
Epithelial hyperplasia, Inflammation	Altered Intercellular Communication	Histology shows mild epithelial hyperplasia, severe inflammation and vessel proliferation in the corion.	19488571
Inflammation, physiopathological	Altered Intercellular Communication	Morphological alterations occur in the corion as vessel proliferations, inflammation, and intracytoplasmatic alterations in fibroblasts suggesting cellular dysfunction and damage.	19488571
Proctitis, organic disease	Altered Intercellular Communication	In conclusion, fecal calprotectin was found to be strongly associated with colorectal inflammation indicating organic disease.	19488608
Inflammation, Oculovestibuloauditory syndrome, Vasculitis, CTCAE, Autoimmune Disorder, CTCAE	Altered Intercellular Communication	Cogan's syndrome is a rare autoimmune disorder characterized by systemic vasculitis as well as eye and ear inflammation.	19488953
Tissue damage, Inflammatory abnormality of the eye	Altered Intercellular Communication	In some BD patients, latent tissue damage caused by recurrent ocular inflammation is not reflected by visual acuity or ophthalmoscopic findings.	19489762
Skin Diseases, Vesiculobullous, Inflammation	Altered Intercellular Communication	However, the initial vesiculobullous stage of IP is characterized histopathologically by eosinophilic inflammation, which is expected to respond to corticosteroids.	19489863
Anguilla island, Asthma, Nasal Polyps, Asthma, Aspirin-Induced, Inflammatory disease of mucous membrane, Rhinitis	Altered Intercellular Communication	Aspirin-intolerant asthma (AIA) is a subtype of asthma induced by non-steroidal anti-inflammatory drugs and characterized by an aggressive mucosal inflammation of the lower airway (asthma) and the upper airways (rhinitis and nasal polyp).	19489917
Inflammatory, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Our case is unique for several reasons: inflammation was limited to the epicardium (very few cases have been described to date); the patient was asymptomatic, with no clinical or echocardiographic evidence of constriction (this represents a novel finding, explained in part by the more limited extent of inflammation, with no significant fibrotic component and no parietal pericardial involvement); and this is the first report of epicarditis occurring in association with a malignancy, which we hypothesize may represent an inflammatory paraneoplastic process.	19490015
Inflammation, Heart Valve Prosthesis	Altered Intercellular Communication	Lipid-mediated inflammation and degeneration of bioprosthetic heart valves.	19490057
Nasal inflammation	Altered Intercellular Communication	These patients clearly differed from typical forms, especially for the nasal inflammation.	19490808
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Endothelial dysfunction, Homocysteinemia	Altered Intercellular Communication	Homocysteinemia may play an etiologic role in the pathogenesis of type 2 diabetes by promoting oxidative stress, systemic inflammation, and endothelial dysfunction.	19491213
Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	NSIP/P was subdivided into cellular NSIP and fibrosing NSIP according to the proportions of interstitial inflammation and fibrosis.	19491520
Inflammation, Corneal Endothelial Cell Loss	Altered Intercellular Communication	After 14 months changes in most markers of inflammation, endothelial damage, and glycemic control were more beneficial in the intervention group.	19491687
Poi serotype, Postoperative ileus, Gastrointestinal inflammation	Altered Intercellular Communication	Although postoperative ileus (POI) is considered multifactorial, intestinal inflammation resulting from manipulation-induced mast cell activation is recognized as an important pathophysiological mechanism.	19491822
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Significant histology was defined as stage > or = 2 fibrosis or stage 1 fibrosis plus grade > or = 2 inflammation using the Batts-Ludwig scoring system.	19491836
Inflammation, Prostate carcinoma, Disseminated Intravascular Coagulation, Thrombophilia	Altered Intercellular Communication	Collectively, our findings suggest that TF-specific PCA of plasma MPs contributes to intravascular coagulation activation in patients with early-stage prostate cancer and may represent a potential link between hypercoagulability, inflammation, and disease progression.	19492160
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Almost all (95%) of the patients with osteoarthritis had no signs of inflammation at the time of screening.	19494370
Inflammation, Atheroma, Coronary heart disease	Altered Intercellular Communication	Gender gap, inflammation and acute coronary disease: are women resistant to atheroma growth?	19494403
Inflammation, Atheroma, Calcinosis	Altered Intercellular Communication	The severity of luminal stenosis and the frequency of adventitial inflammation, intimal calcification and atheromas were determined microscopically for each segment.	19494403
Delusions, CTCAE, "Alzheimers Disease", Psychotic symptom, Hallucinations	Altered Intercellular Communication	Although the etiology of psychotic symptoms (hallucinations and delusions) in Alzheimer's disease is still not known, alterations in serotonergic neurotransmission have been proposed.	19494443
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	In contrast, recent evidence suggests that IL-17-producing Th17 cells play a crucial role in autoimmune inflammation.	19494507
Inflammation, diabetic	Altered Intercellular Communication	Our results showed that nonobese diabetic patients at low cardiovascular risk had similar levels of subclinical markers of inflammation and fibrinolysis as matched healthy controls.	19494532
Neoplasm Metastasis	Altered Intercellular Communication	The purpose of this study is to examine the association between inflammation-related genetic polymorphisms and lymph node metastasis.	19495883
Neoplasm Metastasis	Altered Intercellular Communication	We then assessed the association between inflammation-related genes and lymph node metastasis.	19495883
Airway structure, Atopy	Altered Intercellular Communication	However, the association between the severity of EIB and FE(NO) is present and FE(NO) significantly predictive of EIB only in atopic subjects, suggesting different interaction between bronchial responsiveness and airway inflammation in non-atopic wheeze.	19496956
Inflammation	Altered Intercellular Communication	Future studies will clarify whether the presence of peripheral inflammation plays a mechanistic role in CAD evolution.	19497509
Malnutrition, Infection	Altered Intercellular Communication	Inflammation markers and malnutrition as risk factors for infections and impaired health-related quality of life among older nursing home residents.	19497548
Inflammation, Malnutrition, Infection	Altered Intercellular Communication	To explore malnutrition and inflammation markers as risk factors for poor outcome such as infections and impaired health-related quality-of-life (HRQoL) among nursing home residents.	19497548
Inflammation, Infection	Altered Intercellular Communication	None of the other inflammation markers were associated with the number of infections or with HRQoL.	19497548
Inflammation, Coronary Arteriosclerosis, Metabolic Syndrome X	Altered Intercellular Communication	Chemerin is associated with markers of inflammation and components of the metabolic syndrome but does not predict coronary atherosclerosis.	19497986
Inflammation, Obesity, Atherosclerosis	Altered Intercellular Communication	Given the convergence of adipocyte and macrophage function, chemerin may provide an interesting link between obesity, inflammation and atherosclerosis in humans.	19497986
Inflammation, Metabolic Syndrome X, Plaque, Atherosclerotic	Altered Intercellular Communication	We sought to examine the relationship of i) chemerin and markers of inflammation, ii) chemerin and components of the metabolic syndrome, and iii) chemerin and coronary atherosclerotic plaque burden and morphology.	19497986
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Chemerin is strongly associated with markers of inflammation and components of the metabolic syndrome.	19497986
Inflammation, Vascular Alterations, Radiation-Induced Cancer, Ischemia	Altered Intercellular Communication	Radiation-induced brain injury (RBI) is an insidious side-effect of radiotherapy mediated by vascular alterations, inflammation and ischaemia.	19499176
Inflammation, Hodgkin Disease	Altered Intercellular Communication	Analysis of 18F-FDG PET diffuse bone marrow uptake and splenic uptake in staging of Hodgkin's lymphoma: a reflection of disease infiltration or just inflammation?	19499219
Sepsis, Inflammation	Altered Intercellular Communication	Peri-appendicitis is the serosal inflammation of the appendix, which is generally caused by extra-appendicular sepsis.	19499688
Acute inflammation, Perforation (observation)	Altered Intercellular Communication	At laparotomy, a 0.5 cm perforation was observed, localised at the distal ileum and the appendix was oedematous and hyperaemic, consistent with acute inflammation.	19499688
Inflammation, Acute Kidney Insufficiency	Altered Intercellular Communication	The three postoperative factors and risk scores were ("three I's") 1) unplanned intensive care unit admission = 4.0; 2) systemic inflammation = 3; and 3) acute renal impairment = 2.5.	19499858
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The nuclear factor-kappaB (NF-kappaB) family is a set of transcription factors with key roles in the induction of the inflammatory response and may be the link between inflammation and cancer development.	19500386
AURKAIP1 gene, Inflammation, Autoimmune Pancreatitis	Altered Intercellular Communication	Autoimmune pancreatitis (AIP) is characterized by lymphoplasmocytic inflammation, high serum IgG4 concentrations, and a favorable response to corticosteroid treatment.	19500628
Inflammation	Altered Intercellular Communication	Additionally, G-CSF reduced systemic inflammation indicated by suppression of the production or activity of major pro-inflammatory cytokines in plasma.	19500657
Neoplasms, Optic Nerve Glioma, Neoplasms, Vascular Tissue, Orbital Pseudotumor, Adult Non-Hodgkin Lymphoma	Altered Intercellular Communication	Median uptake ratios of other tumors were vascular anomalies/vascular tumors, 1.2 (range, 0.5-3.3); non-Hodgkin lymphomas, 2.9 (range, 0.9-4.2); optic nerve gliomas, 1.5 (range, 0.2-3.3); and idiopathic orbital inflammation, 1.6 (range, 1.4-1.9).	19500849
Inflammation, Fibrosis Assessment, Pancreatitis	Altered Intercellular Communication	High Ras activity mimicking levels in PDAC led to acinar cell senescence and generated inflammation and fibrosis resembling the histologic features of chronic pancreatitis.	19501586
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Every imbalance in the accumulation of senescent cells between the immune system and the potential target organs can initiate a chronic inflammation or autoimmunity.	19501986
ARCN1 gene, Communicable Diseases, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Latent adenoviral infection may amplify cigarette smoke-induced lung inflammation and therefore play an important role in the development of chronic obstructive pulmonary disease (COPD).	19502044
Osteitis, Fracture	Altered Intercellular Communication	In the group treated by open reposition and plate fixation, we found the following complications that might impede bone union: plate fracture, technical errors, screw loosening, bone inflammation, and other complications.	19502670
Inflammation, Werner Syndrome	Altered Intercellular Communication	The Werner syndrome protein affects the expression of genes involved in adipogenesis and inflammation in addition to cell cycle and DNA damage responses.	19502800
Crohn Disease, Inflammation	Altered Intercellular Communication	Long-term outcomes included acute pouchitis (antibiotic responsive), chronic pouchitis (antibiotic dependent or refractory), or de novo Crohn's disease (small inflammation above the pouch inlet or pouch fistula).	19502850
Ileitis	Altered Intercellular Communication	Inflammation proximal to the pouch, prepouch ileitis (PPI) has recently been described.	19502851
Inflammation	Altered Intercellular Communication	All of the patients had concurrent pouch inflammation, and in this group the incidence was 13 percent.	19502851
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The incidence of PPI in patients with ulcerative colitis/indeterminate colitis is 5.7 percent, and it occurs in 13 percent of patients with pouch inflammation.	19502851
Inflammation	Altered Intercellular Communication	All of the patients had associated pouch inflammation; however, not all of the patients were symptomatic.	19502851
Inflammation, Mandibular Condyle, Fibrosis Assessment, Structure of mandibular nerve, Sinusitis	Altered Intercellular Communication	Nineteen patients (54%) had abnormalities comprising radiotherapy-induced masticator muscle fibrosis (n = 19), denervation atrophy of the masticator muscles secondary to mandibular nerve damage (n = 1), mandibular ramus signal abnormalities (n = 5), mandibular condyle sclerosis with or without capsular thickening (n = 5), perimasticator fibrosis extending into the masticator space (n = 3) and inflammation secondary to severe sinusitis extending into the masticator space (n = 2).	19504110
Inflammation, Prostate carcinoma	Altered Intercellular Communication	The purpose of this study was to investigate two markers of gut inflammation during and after irradiation for prostate cancer to evaluate a correlation between acute and chronic proctitis.	19504404
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The findings of magnifying colonoscopy in patients with quiescent UC is useful for predicting relapse and is associated with histological grade of inflammation.	19504617
Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn, Edema	Altered Intercellular Communication	Acute respiratory distress syndrome (ARDS) is characterized by diffuse inflammation in the lung and resultant permeability edema.	19506468
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	The role of DCs (dendritic cells) as potent mediators of inflammation has not been sufficiently investigated in stroke.	19508233
Gingivitis, Calculi	Altered Intercellular Communication	The Community Periodontal Index (CPI) was used to report the occurrence of probing pocket depth, calculus, and gingival inflammation.	19508245
Vasculitis, Leukocytoclastic, Cutaneous, Inflammation	Altered Intercellular Communication	Leucocytoclastic vasculitis (LV) is characterized by necrotizing inflammation around small blood vessels, composed mainly of neutrophils and their debris.	19508466
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Complications of Diabetes Mellitus	Altered Intercellular Communication	OBJECTIVE Subclinical inflammation is an important risk factor for type 2 diabetes and diabetes complications.	19509015
Inflammation, Diabetic Foot	Altered Intercellular Communication	However, data on the association between inflammation and acute diabetic foot syndrome are scarce.	19509015
Communicable Diseases, Inflammation, Ulcer	Altered Intercellular Communication	In multivariate models, size of ulcer according to the University of Texas classification but not the grade of infection was independently associated with three markers of subclinical inflammation (CRP, IL-6, and fibrinogen).	19509015
Adrenal Gland Hyperfunction, Inflammation	Altered Intercellular Communication	Despite long-term cure, patients who have suffered CS exhibit persistent accumulation of central fat, as in active hypercortisolemia, with the consequent unfavorable adipokine profile, leading to a state of low-grade inflammation.	19509101
Inflammation, Corneal Ulcer, Epithelial	Altered Intercellular Communication	Signs were redness (100%), epithelial defects (98.3%), superficial corneal ulcer (95.1%), anterior chamber inflammation (91.8%), and satellite infiltrates (75.4%).	19512910
Inflammation, Abnormality of the vasculature, Articulation Disorders	Altered Intercellular Communication	These results demonstrated that, in the tongue of chagasic patients, a microvascular abnormality and immunological impairment occurs, probably due to chronic inflammation evoked by T. cruzi antigens.	19513749
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	[Acute inflammation phase reactants and interleukin-8 in myocardial infarction].	19514335
Inflammation, Lung diseases	Altered Intercellular Communication	There was probably specific inflammation around bronchioles, and the inflammation might have spread to the alveolar region in such cases with severe pulmonary function disorder.	19514496
Abscess of orbit, Traumatic injury	Altered Intercellular Communication	The third case, a 69-year-old male with a right orbit abscess following a trauma with a tree branch had a persistent right orbit inflammation lasting 4 months despite two drainage surgeries and an extraction of an orbital organic foreign body.	19515307
Diabetes Mellitus, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Besides its well appreciated role in diabetes, obesity, and metabolic syndrome, insulin resistance (IR) is associated with smoking, use of hormonal contraceptives, androgens, glucocorticoids, beta-adrenergic blockers, thiazide diuretics, intake of food with high glycaemic index, and reduced physical activity.	19515499
Inflammation, Blood Clot	Altered Intercellular Communication	Here we investigated the relationship between MCs and inflammation, neovascularization, and the presence of intraluminal thrombus in human AAA.	19515525
Inflammation, Hypertension, CTCAE, Cardiovascular Diseases	Altered Intercellular Communication	Because inflammation is known to be related with several cardiovascular diseases, we sought to determine whether C-reactive protein (CRP) might precede the onset of hypertension.	19516173
Presenile dementia, Impaired cognition	Altered Intercellular Communication	However, besides altered acetylcholine transmission, other neurotransmitter systems are involved in cognitive dysfunction leading to dementia.	19516251
Fibrosis, Liver, Inflammation	Altered Intercellular Communication	Acquisition of HCV during this time could have further skewed this response resulting in massive hepatocyte destruction, inflammation, and subsequent liver fibrosis.	19519227
Chronicity, Communicable Diseases, Inflammation	Altered Intercellular Communication	Bacterial infection impairs the healing process, promoting the chronicity of inflammation and wounds.	19519855
Inflammation, Asbestos-Related Lung Disorder, Pleural Diseases, Asbestosis	Altered Intercellular Communication	In asbestos-related disorders, markers of inflammation and oxidative stress are significantly elevated in subjects with asbestosis compared with healthy individuals but not in pleural diseases.	19520561
Inflammation	Altered Intercellular Communication	High-sensitivity C-reactive protein (hs-CRP) is a sensitive systemic marker of inflammation, and increased levels of hs-CRP are associated with inflammatory reactions.	19521085
Chronic liver disease, Prostatic Neoplasms	Altered Intercellular Communication	We excluded patients receiving hormonal ablation for prostatic neoplasm and patients with chronic liver or renal disease and patients receiving corticosteroids.	19521700
Inflammation	Altered Intercellular Communication	In particular, in 23 out of 28 (82%) patients with positive H pylori antibodies, a likely cause of IDA was found because of the active inflammation involving the gastric body.	19522025
Inflammation, Hemorrhage, Intestinal Obstruction	Altered Intercellular Communication	It is usually asymptomatic but approximately 4% are symptomatic with complications such as bleeding, intestinal obstruction, and inflammation.	19522035
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive lung disease (COPD) is characterised by partially reversible usually progressive airflow limitation caused by inflammation and remodelling.	19522160
Inflammation, Dermatitis, Granuloma	Altered Intercellular Communication	The sample taken from the inflammation on the chest wall was analyzed with PCR method which resulted positive for Acid Fast Bacilli (AFB), tissue biopsy showed dermatitis with granulomata and sputum was positive for AFB.	19522164
Labia Majora Carcinoma, Inflammation	Altered Intercellular Communication	We present the case of a 44-year-old woman with eruptive syringoma of the labia majora and prominent lymphocytic inflammation in the acrosyringium.	19522848
Inflammation, Acute Coronary Syndrome, Systolic dysfunction	Altered Intercellular Communication	Comparison of the long-term prognostic value of cystatin C to other indicators of renal function, markers of inflammation and systolic dysfunction among patients with acute coronary syndrome.	19523634
Renal Insufficiency, Inflammation, Systolic dysfunction, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	We compared the long-term prognostic efficacy of Cys-C with other markers of renal dysfunction, inflammation and systolic dysfunction in patients with ACS.	19523634
Inflammation, Platelet aggregation	Altered Intercellular Communication	Ancillary effects include increased platelet aggregability, increased sympathic activation, oxidative stress, vascular endothelial dysfunction, inflammation, and metabolic dysregulation.	19523714
Fever, CTCAE	Altered Intercellular Communication	Inflammation of unknown origin versus fever of unknown origin: two of a kind.	19524186
Inflammation, Crohn Disease	Altered Intercellular Communication	Quantitative analysis of dynamic contrast enhanced MRI for assessment of bowel inflammation in Crohn's disease pilot study.	19524458
Inflammation	Altered Intercellular Communication	Receiver-operating characteristic analysis was performed to compare the diagnostic accuracy of the parameters in the task of distinguishing normal tissue from inflammation.	19524458
Inflammation, Crohn Disease	Altered Intercellular Communication	These preliminary results demonstrate that the quantitative analysis of DCE-MRI data is possible for the assessment of bowel inflammation in patients with Crohn's disease.	19524458
amyloid-beta binding, Inflammation	Altered Intercellular Communication	Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice.	19524673
germinal vesicle, Graafian Follicle	Altered Intercellular Communication	The fact that germinal vesicle-stage oocytes were present in our patient's medium despite hormonal down-regulation demonstrates that GnRH agonist does not completely inhibit antral follicle development.	19524895
prostatitis	Altered Intercellular Communication	In asymptomatic men with mild increases of prostate specific antigen histological evidence of prostatic inflammation is common.	19524953
prostatitis	Altered Intercellular Communication	Our data suggest that 10 leukocytes per high power field in post-prostatic massage urine, the usually applied cutoff, may be too high for the definition of prostatic inflammation.	19524953
Inflammation, Demyelination, Multiple Sclerosis, Nerve Degeneration	Altered Intercellular Communication	Demyelination, inflammation, and neurodegeneration in multiple sclerosis deep gray matter.	19525897
Inflammation, White matter lesions	Altered Intercellular Communication	Inflammation in DGM lesions is intermediate between the destructive inflammation of white matter lesions and the minimal inflammation of cortical lesions.	19525897
Refractory anemias, Arthritis	Altered Intercellular Communication	FDG uptakes in joint lesions with MESC were much higher than those reported in typical lesions of RA, suggesting that marked joint inflammation is implicated in the development of MESC.	19526305
Inflammation, Traumatic injury	Altered Intercellular Communication	Ischaemia/reperfusion induces systemic inflammation and oxidative stress and thereby remote organ injury in the kidney.	19526394
Inflammation, Acute Coronary Syndrome, Dental Plaque, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation caused by activated macrophages and T lymphocytes may trigger plaque rapture in acute coronary syndrome (ACS).	19527302
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Perifollicular inflammation was almost a constant feature in early cases and showed a significant inverse correlation with perifollicular fibrosis (P = 0.048), which was more marked with thickening of the follicular sheath in advanced cases.	19527330
Neoplasms	Altered Intercellular Communication	These tumors are mainly benign and show typical luteinization associated with the hormonal milieu in pregnancy.	19527401
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	We evaluated: (i) whether fecal supernatants from patients with ulcerative colitis (UC) trigger alterations of colonic paracellular permeability and inflammation, and (ii) the roles of cathepsin G (Cat-G), a neutrophil serine protease, and its selective receptor, PAR(4), in these processes.	19528350
Inflammation, Familial Mediterranean Fever	Altered Intercellular Communication	The precise pathologic mechanism is still to be definitively elucidated; however a new macromolecular complex, called inflammasome, seems to play a major role in the control of inflammation and it might be involved in the pathogenesis of FMF.	19530512
Necrotizing granulomatous inflammation, Muscle Rigidity	Altered Intercellular Communication	The first case had chronic granulomatous inflammation induced by the PDMS and the second a periprothetic fibrotic reaction causing cordal rigidity.	19530528
Inflammation	Altered Intercellular Communication	In case of chronic inflammation, an endoscopic removal is indicated.	19530528
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Inflammation is implicated in chronic heart failure (CHF).	19531154
vascular inflammations, Congestive heart failure	Altered Intercellular Communication	This PPARalpha activator may have the potential to ameliorate vascular inflammation in patients with CHF.	19531154
Inflammation, Chemical injury	Altered Intercellular Communication	Ischemic injury and inflammation resulting from inadequate resuscitation might influence organ yield for transplantation.	19531941
Nonulcer dyspepsia, Dysautonomia, Familial, Inflammation	Altered Intercellular Communication	Although inflammatory changes in the gastric mucosa are commonly observed in Japanese patients with functional dyspepsia (FD), detailed data regarding the relationship between the genetic regulatory factors of inflammation and FD are not available.	19531958
Inflammation, Helicobacter Pylori-Related Carcinoma	Altered Intercellular Communication	Superoxide has been implicated in the pathogenesis of Helicobacter pylori-related diseases through inflammation.	19531958
Congenital neutropenia, Amyloidosis	Altered Intercellular Communication	We report about a patient with congenital neutropenia, AA amyloidosis and chronic intestinal bowel inflammation due to amyloid deposition in the bowel.	19533073
Sepsis, Inflammation	Altered Intercellular Communication	High-mobility group box 1 (HMGB1) is a late mediator of the systemic inflammation associated with sepsis.	19533845
Inflammation, Hemorrhage, Meckel Diverticulum, Intestinal Obstruction	Altered Intercellular Communication	Complications like intestinal obstruction, bleeding and inflammation of Meckel's diverticulum occur in 4% of patients.	19534380
Inflammation, Atheroma, Cardiovascular Diseases	Altered Intercellular Communication	Elevated blood levels in cardiovascular disease and local deposition in atheroma implies a role of SAA as a mediator rather than just a marker of inflammation.	19535079
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Outcome predictability of biomarkers of protein-energy wasting and inflammation in moderate and advanced chronic kidney disease.	19535427
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Markers of protein-energy wasting (PEW) and inflammation are common in chronic kidney disease (CKD) and are among the strongest predictors of mortality in dialysis patients.	19535427
Inflammation	Altered Intercellular Communication	We hypothesized that markers of PEW and inflammation show similar associations in patients with non-dialysis-dependent CKD (NDD-CKD).	19535427
Hypertension, CTCAE, Myelolipoma of adrenal gland, Neoplasms, Obesity	Altered Intercellular Communication	Adrenal myelolipoma is an uncommon tumour of the adrenal gland, usually unilateral, frequently associated with hypertension and obesity, with a benign biological behaviour and without hormonal activity, first described in 1905.	19536999
Inflammation, Heat-Shock Response	Altered Intercellular Communication	Fasting blood plasma was analysed for glucose, lipids, markers systemic inflammation, cytokines and antibodies against heat shock proteins (Hsp).	19538326
Inflammation, Impaired cognition	Altered Intercellular Communication	Chronic subclinical inflammation may elevate the risk of cognitive impairment.	19538327
Inflammation, Periodontitis, Tooth Loss	Altered Intercellular Communication	Periodontitis is associated with subclinical inflammation and accounts in part for tooth loss.	19538327
Arterial Stiffness, Inflammation, Acute Kidney Injury, CTCAE	Altered Intercellular Communication	Assessment of arterial stiffness, oxidative stress and inflammation in acute kidney injury.	19538714
Arterial Stiffness, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	It is well know that arterial stiffness, oxidative stress and inflammation are features of chronic kidney disease.	19538714
Inflammation, Endothelial dysfunction, Vascular calcification, Atherosclerosis	Altered Intercellular Communication	The arterial changes have a multitude of potential interconnected causes including endothelial dysfunction, oxidative stress, inflammation, atherosclerosis and vascular calcification.	19538714
Inflammation, Hematemesis	Altered Intercellular Communication	Four patients presented with sudden massive hematemesis whereas 2 patients were readmitted for new-onset fever and elevated markers of inflammation that preceded hematemesis.	19539264
Inflammation, Pustulosis of Palms and Soles, Acne, Synovitis, Osteitis, Sapho, Hyperostosis	Altered Intercellular Communication	Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a clinically heterogeneous entity, encompassing a variety of debilitating conditions that have in common inflammation of the skeletal system and skin.	19539848
ARCN1 gene, Inflammation	Altered Intercellular Communication	Currently, limited data are available about determining factors of systemic inflammation in COPD, in particular C-reactive protein (CRP).	19540024
ARCN1 gene, Inflammation	Altered Intercellular Communication	These findings are suggestive for an adipocyte-induced systemic inflammation in COPD.	19540024
Sepsis, Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	The combined determination of MIF and PCT might, therefore, be useful to discriminate between post-burn inflammation and systemic inflammatory response syndrome (SIRS) or sepsis with lethal outcome.	19540674
Hematoma, Pseudoaneurysm	Altered Intercellular Communication	Five malignant and 14 benign histologies (including 6 types with inflammation-related, hematoma or pseudoaneurysm) occurred that had more than 10 subjects with each histology.	19541566
Inflammation, hepcidin	Altered Intercellular Communication	Serum hepcidin-25 is increased in hemodialysis patients, regulated by iron stores and inflammation, and relatively reduced in subjects carrying frequent HFE mutations.	19541813
Inflammation, Damage, Demyelination	Altered Intercellular Communication	Multiple sclerosis is a disease that is characterized by inflammation, demyelination, and axonal damage; it ultimately forms gliotic scars and lesions that severely compromise the function of the central nervous system.	19541935
palladium, Inflammation	Altered Intercellular Communication	These observations suggest that the alteration in PG components following PD therapy and severe inflammation contribute to fibrous thickening of the peritoneum.	19542195
Airway structure	Altered Intercellular Communication	DAC patients who underwent HRCT scanning compared with those who did not were older, had longer disease duration, had poorer lung function, were receiving higher doses of corticosteroids, and had increased neutrophilic airway inflammation.	19542254
ARCN1 gene, Inflammation, Metabolic Syndrome X, Bronchitis	Altered Intercellular Communication	The metabolic syndrome in patients with chronic bronchitis and COPD: frequency and associated consequences for systemic inflammation and physical inactivity.	19542257
ARCN1 gene, Inflammation	Altered Intercellular Communication	Systemic inflammation and physical inactivity are relevant extrapulmonary markers of morbidity and mortality in patients with COPD.	19542257
ARCN1 gene, Inflammation, Metabolic Syndrome X, cinobufotalin, Bronchitis, Chronic	Altered Intercellular Communication	Here, we studied the following: (1) the frequency of the coexisting metabolic syndrome in patients with chronic bronchitis (CB) and COPD of different severities; and (2) its association with systemic inflammation and physical inactivity.	19542257
ARCN1 gene, Inflammation, Metabolic Syndrome X, Chronic Obstructive Airway Disease, gold	Altered Intercellular Communication	In 30 patients with CB (normal spirometry finding) and in 170 patients with COPD (Global Initiative for Chronic Obstructive Lung Disease [GOLD] stages I to IV), we measured the characteristics of the metabolic syndrome, systemic inflammation (high-sensitivity C-reactive protein [hs-CRP], interleukin-6, fibrinogen), and the physical activity level.	19542257
Presenile dementia, Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Systemic inflammation and the risk of Alzheimer's disease and dementia: a prospective population-based study.	19542629
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation is suggested to be involved in the pathogenesis of Alzheimer's disease (AD).	19542629
Airway structure, Asthma, Chest Pain	Altered Intercellular Communication	The results suggest that the mechanism underlying chest pain that is relieved with asthma drugs can involve either an airway constriction pathway or a non-constrictive pathway presumably airway inflammation.	19542762
Multiple Myeloma, Inflammation	Altered Intercellular Communication	The main changes evidenced were ingrowing of the squamous epithelium (either from the matrix or mostly from the hyponichium) and chronic plasma-cell rich inflammation with prominent vascularization.	19542917
Inflammation, Organ Dysfunction Scores, Critical Illness	Altered Intercellular Communication	Serum resistin levels in critically ill patients are associated with inflammation, organ dysfunction and metabolism and may predict survival of non-septic patients.	19545363
Inflammation, Critical Illness	Altered Intercellular Communication	Therefore, resistin might represent a link between inflammation, acute phase response and insulin resistance in critically ill patients.	19545363
Inflammation, Critical Illness	Altered Intercellular Communication	We aimed to examine the correlation of serum resistin concentrations to parameters of inflammation, organ function, metabolism, disease severity and survival in critically ill patients.	19545363
Sepsis, Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	Serum resistin concentrations are elevated in acute inflammation due to sepsis or systemic inflammatory response syndrome (SIRS).	19545363
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Thus, the predominant features of global orbital metastatic cancer versus primary inflammation are highlighted in this presentation.	19545850
Pancreatitis	Altered Intercellular Communication	Serum amylase and lipase measurements are known biochemical markers of pancreatic inflammation and a recognized finding that may help diagnose acute pancreatitis.	19548460
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	Crohn's Disease (CD), a chronic intestinal inflammation, is currently treated primarily by therapeutics which are directed against inflammatory responses.	19549264
Inflammation, Diabetic Retinopathy	Altered Intercellular Communication	There are conflicting data regarding relationships of systemic biomarkers of inflammation, hemostasis, and homocysteine with diabetic retinopathy.	19549733
Inflammation, Diabetic Retinopathy	Altered Intercellular Communication	There were few associations of novel markers of inflammation, hemostasis, and homocysteine with diabetic retinopathy after controlling for established risk factors.	19549733
Malignant tumor of colon, Inflammation	Altered Intercellular Communication	Because chronic inflammation is implicated in several pathologic conditions in humans, including cancers of the colon, anti-inflammatory compounds may be useful chemopreventive agents against colon cancer.	19549798
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) are among the sensitive markers of systemic inflammation.	19551157
Filariasis, Periorbital region	Altered Intercellular Communication	The clinical presentation of filariasis is not always straightforward, and a high index of suspicion is necessary in cases presenting with orbital or periorbital inflammation.	19551686
Fibrous	Altered Intercellular Communication	Stenoses were inflammation-dominated with various narrowing of the lumen (type I) in 16.1% of patients, fibrous and web-associated, predominant incomplete (luminal narrowing <50%, type II) in 18.3%, and fibrous, predominant high-grade (luminal narrowing >50%, type III) in 66.6%.	19551851
Inflammation, Venous Thrombosis	Altered Intercellular Communication	Common hemostasis and inflammation gene variants and venous thrombosis in older adults from the Cardiovascular Health Study.	19552680
Inflammation, Thrombosis, vinyltriethoxysilane	Altered Intercellular Communication	We tested 290 common SNPs within 51 thrombosis and inflammation genes for association with VTE in the Cardiovascular Health Study, a large, prospective cohort of older adults followed for up to 12 years.	19552680
Choroidal Neovascularization, Inflammation, Fibrosis Assessment, neuron death	Altered Intercellular Communication	The focus on more effective blockade of choroidal neovascularization has shifted to include control of additional processes implicated in disease progression, such as neural death, inflammation, or fibrosis.	19553800
Inflammation, Fibrosis Assessment, Choroidal Neovascularization, Unspecified visual loss	Altered Intercellular Communication	Although there is likely to be a strong interrelationship between choroidal neovascularization and inflammation that contributes to advanced stages of disease progression, including fibrosis, combining treatment strategies may enlarge the opportunity to prevent both early and late vision loss.	19553800
Inflammation	Altered Intercellular Communication	Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events?	19554082
Brain Injuries	Altered Intercellular Communication	We hypothesized that markers of brain damage discovered by proteomic strategies and inflammation-related proteins could individually or in combination indicate the CNS invasion by the parasite.	19554086
Inflammation	Altered Intercellular Communication	It usually involves one hemisphere with focal cortical inflammation.	19555404
Inflammation, Hepatobiliary Disorder, Non-alcoholic Fatty Liver Disease, Fibrosis Assessment	Altered Intercellular Communication	Non-alcoholic fatty liver disease (NAFLD) is a spectrum of liver disease characterised by accumulation of large-droplet fat in hepatocytes with possible progression to inflammation and fibrosis.	19556219
Inflammation	Altered Intercellular Communication	Lack of response in 12% of cases suggests the presence of not screened viruses or mechanisms of damage and inflammation not susceptible to immunosuppression.	19556262
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	However, PET is affected by several factors, including diabetes and inflammation.	19556380
Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Chronic inflammation is implicated in idiopathic pulmonary fibrosis (IPF) pathogenesis and is associated with persistent activation of immune responses.	19556741
Airway structure, Asthma	Altered Intercellular Communication	The fractional concentration of exhaled nitric oxide (FeNO) appears to be a good marker for airway inflammation in children with asthma.	19557209
Airway structure	Altered Intercellular Communication	Exposure to different types of pets may have disparate effects on airway inflammation.	19557209
Inflammation	Altered Intercellular Communication	In the central nervous system glial-derived S100B protein has been associated with inflammation via nitric oxide (NO) production.	19558426
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Systemic chemerin is related to inflammation rather than obesity in type 2 diabetes.	19558533
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	The adipokine chemerin modulates the function of innate immune cells and may link obesity and inflammation, and therefore, a possible relation of chemerin to inflammatory proteins in obesity and type 2 diabetes (T2D) was analysed.	19558533
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	As visceral fat contributes to systemic inflammation, chemerin was measured in portal venous (PVS), hepatic venous (HVS) and systemic venous (SVS) blood of patients with liver cirrhosis.	19558533
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Visceral fat is not a major site of chemerin release, and elevated systemic levels of chemerin in obesity and T2D seem to be associated with inflammation rather than body mass index.	19558533
Tolosa-Hunt Syndrome, Cranial third nerve paresis, Methylated spirit, Necrotizing granulomatous inflammation	Altered Intercellular Communication	Tolosa-Hunt syndrome (THS) is characterized by unilateral painful ophthalmoplegia with oculomotor paresis, associated with an idiopathic granulomatous inflammation involving the cavernous sinus, with a typical relapsing-remitting course.	19558537
Deficiency of butyryl-CoA dehydrogenase, Inflammation	Altered Intercellular Communication	Endoscopic patterns of SCAD may range from mild to severe inflammation.	19558591
Inflammation, Cardiovascular Diseases, Acidosis, Anemia, Sarcopenia, Hypertension, CTCAE, Chronic Kidney Diseases	Altered Intercellular Communication	The odds of frailty associated with chronic kidney disease were only marginally attenuated with additional adjustment for sarcopenia, anemia, acidosis, inflammation, vitamin D deficiency, hypertension, and cardiovascular disease.	19559169
Inflammation, Intestines, Small	Altered Intercellular Communication	Previous workup was significant for eosinophilic inflammation in the antrum and a video capsule study showing erythematous lesions in the small bowel.	19559431
Inflammation, Fibrosis Assessment, Fatty degeneration, Fatty Liver Disease, Balloon Dilatation	Altered Intercellular Communication	NASH was defined as steatosis, lobular inflammation, and ballooning degeneration with or without Mallory-Denk bodies and/or fibrosis.	19559819
Presenile dementia, Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	C-reactive protein (CRP) is a nonspecific marker of inflammation that is increased in the brain and serum of patients with Alzheimer's disease (AD), and has been associated with increased risk of developing dementia.	19560102
Presenile dementia, Inflammation	Altered Intercellular Communication	Inflammation increases with age, and the number of people reaching age 90 years and older is growing, making the association between inflammation and dementia increasingly relevant.	19560102
Communicable Diseases, Inflammation	Altered Intercellular Communication	Interleukin-1beta (IL-1beta) is involved in the regulation of sickness behaviour in response to infection and inflammation in animals.	19560535
Inflammation, Sore to touch, Swelling	Altered Intercellular Communication	All of the patients had inflammation, swelling, and localized tenderness.	19560565
Inflammation, Comorbidity	Altered Intercellular Communication	Glomerular filtration rate less than 60 mL/min/1.73 m(2) estimated from serum cystatin C level, comorbidity, medications, and markers of inflammation and hemostasis.	19560852
Peripheral Vascular Diseases, Vascular Diseases, Inflammation	Altered Intercellular Communication	To objectively assess the presence of polyvascular disease in patients with peripheral arterial disease and its relation to inflammation and clinical risk factors.	19560948
Inflammation, Vascular Diseases	Altered Intercellular Communication	The level of systemic inflammation, reflected by hs-CRP levels, is moderately associated with the extent of polyvascular disease.	19560948
Inflammation, Synovial Hypertrophy	Altered Intercellular Communication	Moreover, PD-positive synovial hypertrophy identifies an ongoing inflammation even during remission and predicts short-term relapse.	19561156
Pulmonary Complication, Pneumonitis	Altered Intercellular Communication	Delivery of a potent glucocorticoid such as 17-BMP to the pulmonary artery after oral dosing of BDP may be useful in modulating pulmonary inflammation and preventing the development of non-infectious pulmonary complications after allogeneic HCT.	19561649
Inflammation, Perforation (observation)	Altered Intercellular Communication	The CRP value showed a strong correlation with respect to the grade of inflammation and perforation.	19562239
Pharyngitis, Gorontalo Language	Altered Intercellular Communication	Indeed, in 40% of patients, radiographic signs were found that indicated nonspecific hypertrophy of the lingual tonsil and/or palatine tonsils and nonspecific signs of chronic pharyngeal inflammation, and GORD was identified in 93% of patients, which in 40% of cases extended to the proximal third of the oesophagus.	19562267
Inflammation, hepcidin	Altered Intercellular Communication	Hepcidin, a liver-derived peptide induced by iron overload and inflammation, is a major regulator of iron homeostasis.	19563467
Inflammation, hepcidin, Anemia	Altered Intercellular Communication	We studied the associations between circulating hepcidin levels and various laboratory parameters related to anaemia and/or inflammation in 20 patients on chronic haemodialysis.	19563467
Pyoderma Gangrenosum	Altered Intercellular Communication	Pyoderma gangrenosum, in contrast, is a noninfectious inflammatory condition of the skin that typically does not require surgical management.	19563941
Pain Distress Question, Inflammation, Fever, CTCAE, Communicable Diseases, Adverse Event Associated with Constitutional Symptoms	Altered Intercellular Communication	Back pain in presence of fever, constitutional symptoms, and/or high inflammation markers should alert physicians for spinal infection.	19564756
Inflammation, Neoplasms	Altered Intercellular Communication	Physical examination revealed a huge tumor in the right lower leg without signs of inflammation.	19564830
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Obesity-induced chronic inflammation is a key component in the pathogenesis of insulin resistance and metabolic syndrome.	19565174
Inflammation	Altered Intercellular Communication	It has been suggested that proinflammatory cytokines and low-grade systemic inflammation activate bone resorption and may lead to reduced bone mineral density (BMD).	19565174
Inflammation, Acute anterior uveitis	Altered Intercellular Communication	Enthesis inflammation in recurrent acute anterior uveitis without spondylarthritis.	19565479
Refractory anemias, Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	This study was undertaken to characterize the disease specificity and function of pan-DR-binding Hsp60-derived epitopes as possible modulators of autoimmune inflammation in RA.	19565483
Refractory anemias, Inflammation, Damage	Altered Intercellular Communication	The purpose of this study was to examine the hypothesis that adipocytokines modulate inflammation and radiographic joint damage in patients with RA.	19565493
Refractory anemias, Inflammation	Altered Intercellular Communication	Concentrations of all adipocytokines were significantly higher in RA patients than in controls; for visfatin and adiponectin, this association remained significant after adjusting for BMI, inflammation, or both.	19565493
Refractory anemias, Inflammation	Altered Intercellular Communication	The concentration of OPN was significantly elevated in RA patients and appeared to correlate with the serum levels of inflammation markers and increased expression of MCP-1 or MIP-1beta in monocytes in RA patients.	19565503
Inflammation, Extensively Drug-Resistant Tuberculosis	Altered Intercellular Communication	[Serum nitric oxide level in the assessment of systemic inflammation in patients with drug-resistant pulmonary tuberculosis].	19565813
Inflammation, Mild cognitive disorder, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome, inflammation, and nonamnestic mild cognitive impairment in older persons: a population-based study.	19568151
Inflammation, Impaired cognition, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	The metabolic syndrome (MetS) is more strongly associated with cognitive impairment in the presence of inflammation.	19568151
Inflammation, millicurie, Anomia, ETV3 wt Allele	Altered Intercellular Communication	This study investigated the association between MetS with or without inflammation and MCI [amnestic (a-MCI) and nonamnestic (na-MCI)].	19568151
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	The combined presence of MetS and high levels of inflammation is associated with na-MCI in this elderly cohort, and suggests etiologic differences in MCI subtypes.	19568151
Malignant neoplasm of urinary bladder	Altered Intercellular Communication	Hormonal factors, possibly related to reproductive characteristics, may play a role in the risk of bladder cancer among women.	19568699
Malignant neoplasm of urinary bladder	Altered Intercellular Communication	Women have a lower risk of bladder cancer than men, and hormonal factors related to childbearing may play a role.	19568699
Papilledema, Uveitis	Altered Intercellular Communication	They were treated with high-dose corticosteroid therapy, and several weeks later, both the uveal inflammation and optic disc swelling disappeared.	19568763
Atrial Fibrillation, Atrial Fibrillation by ECG Finding, Hypertension, CTCAE, Inflammation	Altered Intercellular Communication	Numerous evidence has suggested that either hypertension or atrial fibrillation (AF) is associated with systemic inflammation.	19569080
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	The correlation between PPARgamma inflammation and AF is still unknown.	19569080
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	In hypertensive patients, increased inflammatory cytokines were associated with increased incidence of AF and atrial remodeling; PPARgamma may be involved in the pathogenesis of AF by regulation of inflammation.	19569080
Inflammation, Dermatomyositis, Childhood Type	Altered Intercellular Communication	Juvenile dermatomyositis (JDM) is a rare systemic disease of unknown etiology characterized by inflammation of the muscle, skin and digestive tract, with variable outcome.	19569283
Inflammation	Altered Intercellular Communication	Adiponectin plays an important role in the regulation of tissue inflammation and insulin sensitivity.	19570238
Inflammation	Altered Intercellular Communication	This highly important observation may result from a setting of prevailing chronic subclinical inflammation.	19570555
Inflammation, Acute myocardial infarction, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Relation of inflammation and left atrial remodeling in atrial fibrillation occurring in early phase of acute myocardial infarction.	19570585
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation is frequently associated with the development of atrial fibrillation (AF).	19570585
Inflammation, Chronic granulomatous disease	Altered Intercellular Communication	Thus we speculate that the lack of a functional NADPH oxidase results in impaired neutrophil clearance and the exaggerated inflammation that is characteristic for CGD.	19570889
atherosclerotic	Altered Intercellular Communication	Pericardial fat (ie, fat around the heart) may have a direct role in the atherosclerotic process in coronary arteries through local release of inflammation-related cytokines.	19571212
Inflammation, Edema	Altered Intercellular Communication	These data support the hypothesis that, in addition to the adaptive immune responses, the complement system is involved in the pathogenesis of CRSwNP and may contribute to typical features such as edema and granulocytic inflammation.	19572264
Hypoglycemia, Diabetes Mellitus	Altered Intercellular Communication	Comparing hormonal and symptomatic responses to experimental hypoglycaemia in insulin- and sulphonylurea-treated Type 2 diabetes.	19573114
Pain Distress Question, Inflammation, Neoplasms	Altered Intercellular Communication	The patient presented with a tumor in the right breast that had appeared 6 months earlier with no pain, signs of inflammation, or nipple secretion.	19573643
Pneumonitis	Altered Intercellular Communication	The most foolproof way to promote survival in epidemics of potentially lethal influenza is to target, not highly mutable viral proteins, but rather intracellular signaling pathways which promote viral propagation or lung inflammation.	19573997
Inflammation, Influenza	Altered Intercellular Communication	NF-kappaB, activated in influenza-infected lung epithelial cells and macrophages, is one likely target in this regard, as it plays a role both in viral replication and in the excessive lung inflammation often evoked by influenza infection.	19573997
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Metabolic Syndrome X	Altered Intercellular Communication	There is some evidence that chronic obstructive pulmonary disease (COPD) and metabolic syndrome may be related, perhaps through systemic inflammation, which is common to both.	19574332
Inflammation, Kidney Diseases	Altered Intercellular Communication	Blood samples were collected for measurement of vascular risk markers (kidney disease, inflammation, nutrition, calcium phosphate and OPG).	19574342
Inflammatory abnormality of the eye	Altered Intercellular Communication	This report illustrates the spectrum of ocular inflammation caused by accidental inoculation of latex of Euphorbia plant.	19574703
Inflammation, Uveitis	Altered Intercellular Communication	Laboratory investigations for uveitis were negative and the patient required systemic and intensive topical steroids with cycloplegics to control the inflammation.	19574707
Hemorrhage, Traumatic injury, Vascular System Injuries	Altered Intercellular Communication	Bleeding was caused by iatrogenic vessel injury (6 patients), malignancy/inflammation (5 patients) and trauma (3 patients).	19575344
Inflammation, Ulcer	Altered Intercellular Communication	It may contribute to reduced perfusion, poor ulcer healing, and sustained chronic inflammation.	19575355
Inflammation, Bacterial resistance, Restless Legs Syndrome	Altered Intercellular Communication	The aim of this study was to determine if RLS was associated with CD because both are associated with iron deficiency, inflammation, and bacterial overgrowth.	19575360
Inflammation, Inflammatory dermatosis, Pruritus	Altered Intercellular Communication	Topical calcineurin inhibitors such as tacrolimus (FK506) ameliorate cutaneous inflammation and associated pruritus in an array of inflammatory dermatoses.	19575757
Inflammation	Altered Intercellular Communication	In conclusion, these results suggest that the previously reported association between poor fitness and low-grade inflammation may be largely attributable to increased visceral AT accumulation and its associated state of insulin resistance, conditions frequently observed in subjects with poor cardiorespiratory fitness.	19576354
Inflammation, Keratitis, Herpetic	Altered Intercellular Communication	Herpes simplex virus keratitis: histopathologic inflammation and corneal allograft rejection.	19576497
Herpes Simplex Infections, Inflammation, Human herpes simplex virus, Keratitis	Altered Intercellular Communication	To identify whether histopathologic and immunoassay biomarkers of inflammation are predictive for allograft rejection after penetrating keratoplasty (PKP) for herpes simplex virus (HSV) keratitis.	19576497
Keratitis	Altered Intercellular Communication	Although 81% of patients had clinically quiescent disease, histopathology revealed that 74% had active corneal inflammation, a finding that was associated with the presence of clinical neovascularization (P = 0.01).	19576497
Inflammation	Altered Intercellular Communication	Corneal specimens demonstrating inflammation had significantly increased IL-8 (P = 0.0005) and MCP-1 (P = 0.003) levels, and greater immunoreactivity for HLA-DR and ICAM-1 when compared with specimens without inflammation.	19576497
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a key role in the pathogenesis of atherosclerosis and an enhanced inflammatory status has a negative impact on patient outcome.	19577753
Primary malignant neoplasm, Inflammatory abnormality of the eye	Altered Intercellular Communication	Overall and cancer related mortality among patients with ocular inflammation treated with immunosuppressive drugs: retrospective cohort study.	19578087
Inflammatory abnormality of the eye	Altered Intercellular Communication	Patients 7957 US residents with non-infectious ocular inflammation, 2340 of whom received immunosuppressive drugs during follow up.	19578087
Inflammation, Acute Coronary Syndrome, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a pivotal role in the pathogenesis of atherosclerosis and coronary syndromes.	19578791
Inflammation	Altered Intercellular Communication	Data indicate that the complement proteins play a crucial role in the link between inflammation and atherogenesis.	19578791
Refractory anemias, Inflammation	Altered Intercellular Communication	In RA, endothelial activation (as sEsel) correlates with classical markers of inflammation and is reduced by intensive anti-inflammatory medications.	19578810
Granulomatous inflammation	Altered Intercellular Communication	Lung biopsy obtained by wedge resection showed granulomatous inflammation with extensive multinuclear giant cells involving the lung parenchyma and vascular structures.	19578851
Inflammation, Lesion of retina	Altered Intercellular Communication	The macular and retinal lesions, the etiological role of toxic agent, the compression and the inflammation of the optic nerve all have to be excluded.	19579669
Communicable Diseases, inflammation or infection	Altered Intercellular Communication	Procalcitonin role in differential diagnosis of infection stages and non infection inflammation.	19579976
Communicable Diseases, inflammation or infection	Altered Intercellular Communication	The aim of this study is evaluation of procalcitonin role in the diagnosis of infectious and non infectious inflammation.	19579976
Inflammation, Chronic Obstructive Airway Disease, Bronchitis	Altered Intercellular Communication	Among adults <50 years old, chronic bronchitis unaccompanied by airflow limitation may represent an early marker of susceptibility to the effects of cigarette smoking on systemic inflammation and long-term risk for chronic obstructive pulmonary disease and all-cause mortality.	19581277
Inflammation	Altered Intercellular Communication	Laboratory evidence of inflammation was found in 87% and RF in 78% of the patients.	19581382
Refractory anemias, Tumor necrosis, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor-alpha (TNF-alpha) plays a central role in inflammation, and it has been directly implicated in the pathogenesis of rheumatoid arthritis (RA).	19582456
metabolic disturbance, Obesity	Altered Intercellular Communication	To gain insight in the interaction between innate immune system and metabolic disturbances (obesity and insulin resistance), we investigated the relationship between circulating lactoferrin and chronic inflammation-associated insulin resistance according glucose tolerance status in Caucasian population.	19584176
Inflammation, Coronary Artery Disease, Endothelial dysfunction	Altered Intercellular Communication	Inflammation but not endothelial dysfunction is associated with the severity of coronary artery disease in dyslipidemic subjects.	19584917
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Endothelial dysfunction and inflammation play a key role in the development of atherosclerosis.	19584917
Intraocular inflammation, Sarcoidosis, Neurosarcoidosis	Altered Intercellular Communication	We found a higher incidence of ocular manifestations, including intraocular inflammation in neurosarcoidosis compared to that in systemic sarcoidosis elsewhere.	19585359
Intraocular inflammation, Sarcoidosis, Neurologic Symptoms	Altered Intercellular Communication	Patients with neurological symptoms and associated intraocular inflammation should have a routine work-up for sarcoidosis.	19585359
Inflammatory abnormality of the eye	Altered Intercellular Communication	To evaluate the control of ocular inflammation and the steroid sparing effect in patients with sarcoidosis-associated uveitis treated with mycophenolate mofetil (MMF).	19585361
Carcinoma of lung	Altered Intercellular Communication	Our results suggest that hormonal factors, related to early menopause and/or ovary removal, may play a role in the risk of lung cancer.	19585503
Osteoporosis	Altered Intercellular Communication	Hormonal changes associated with ageing predispose to osteoporosis also in men, although secondary causes in the pathogenesis of osteoporosis become more pronounced.	19585908
millicurie, neuron death, Data types - Address	Altered Intercellular Communication	Thus, the available, albeit limited, data suggests that MCI is associated with the early stages of the neurobiological and neuropathological changes that culminate in the florid lesions of AD; including the accumulation of neuritic plaques, neurofibrillary tangles, synaptic and neurotransmitter associated deficits, and significant neuronal cell death.	19585952
Inflammation, Diabetic Foot	Altered Intercellular Communication	Ultrasonographic and thermographic screening for latent inflammation in diabetic foot callus.	19586674
Diabetic Foot, Ulcer	Altered Intercellular Communication	Inflammation within the diabetic foot callus may be an earliest, predicting symptom of foot ulcer developing later.	19586674
Inflammation, diabetic	Altered Intercellular Communication	The inflammation signs were detected by both of the two techniques in 10% of the calli in the diabetic group.	19586674
Inflammation, diabetic	Altered Intercellular Communication	The inflammation signs presented here were specifically observed in the diabetic group.	19586674
Glomerulonephritis, Nephritis	Altered Intercellular Communication	(Monocyte chemoattractant protein 1 MCP-1) has been shown to be locally up regulated in glomerulonephritis and recent studies have pointed out MCP-1 as a promising marker of renal inflammation.	19587833
Delirium	Altered Intercellular Communication	The pathophysiology of delirium remains elusive though neurotransmitters and their precursor large neutral amino acids (LNAAs) may play a role.	19588122
Inflammation	Altered Intercellular Communication	Laboratory tests showed inflammation, with an erythrocyte sedimentation rate of 90 mm/h and C-reactive protein 8 mg/l.	19588143
Vasculitis, Vasculitis, CTCAE, Disease	Altered Intercellular Communication	Vasculitis is a disorder characterized by inflammation of blood vessels.	19588144
Inflammation	Altered Intercellular Communication	In some cases the disease is manifested only with symptoms and signs of systemic inflammation (e.g.	19588144
Inflammation, Glucose Intolerance (disease), Obesity, Cardiovascular Diseases	Altered Intercellular Communication	Obesity leads to increased risk of cardiovascular disease and glucose intolerance, which are phenomena of chronic inflammation.	19588793
Inflammation, Obesity	Altered Intercellular Communication	This study was performed to determine whether a higher body mass index (BMI) and central obesity are associated with low-grade inflammation.	19588793
ACSM3 gene, Subarachnoid Hemorrhage, Aneurysmal, Inflammation Mediators, Cerebral Vasospasm	Altered Intercellular Communication	Cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) has been hypothesized to occur because of both inflammation-mediated sustained contraction of smooth muscle cells and vascular remodeling.	19589197
Acute inflammation	Altered Intercellular Communication	It is concluded that MPO and IL-17 are powerful indicators of acute coronary inflammation, however the data set was very small, so larger prospective studies are required.	19589271
Inflammation	Altered Intercellular Communication	Past work has focused on the role of T cells and myeloid cells in mediating chronic gastrointestinal and systemic inflammation.	19589946
Intraocular inflammation	Altered Intercellular Communication	In the ranibizumab group, there were 2 events of transiently increased intraocular pressure (1.1%) and 1 event (0.53%) of intraocular inflammation following injection.	19590252
Parkinson Disease, Impaired cognition, Pervasive Development Disorder, Presenile dementia	Altered Intercellular Communication	Impairment of multiple neurotransmitter networks, including acetylcholine, may contribute to the cognitive impairment in patients with Parkinson disease with dementia (PDD).	19590387
HD Term Type, Thrombosis, Inflammation	Altered Intercellular Communication	Vascular access thrombosis (VAT) is a major cause of morbidity in chronic hemodialysis (HD) patients and is characterized by chronic inflammation.	19590503
Chronic inflammation	Altered Intercellular Communication	Pulse pressure (PP) is positively associated with chronic inflammation.	19590503
Inflammation, Necrosis, Medial calcification, Intimal proliferation, Adventitia	Altered Intercellular Communication	Both ends of all specimens were evaluated by a blinded pathologist for intimal hyperplasia, medial inflammation, medial calcification, periarterial tissue or fat necrosis, adventitial inflammation, adventitial necrosis, and adventitial neovascularization.	19590587
Inflammation, Intimal proliferation, Necrosis	Altered Intercellular Communication	The distal ends of the TRA group showed significantly more intimal hyperplasia (73.3% vs 21.1%; p = 0.03), periarterial tissue or fat necrosis (26% vs 0%; p = 0.02), and more adventitial inflammation (33.3% vs 0%; p = 0.01) than the distal ends of the NCA group.	19590587
Inflammation, Intimal proliferation	Altered Intercellular Communication	The distal ends of the TRA group also showed significantly more intimal hyperplasia (73.3% vs 26.6%; p = 0.03) and adventitial inflammation (33.3% vs 0%; p = 0.01) than the proximal ends of the same arteries.	19590587
Inflammation, Arterial Injury, Intimal proliferation, Necrosis	Altered Intercellular Communication	Transradial catheterization induces significant histological changes suggestive of radial artery injury limited to the puncture site in the form of intimal hyperplasia, medial inflammation, and tissue necrosis.	19590587
Inflammation, Mineral dust	Altered Intercellular Communication	Proximal airways demonstrated little mineral dust accumulation, but membranous and respiratory bronchioles had wall thickening, remodeling, and inflammation associated with carbonaceous and mineral dust deposition.	19590695
Pain Distress Question, Inflammation, Fever, CTCAE, Brucellosis, Familial Mediterranean Fever, MULTISYSTEM DISORDER	Altered Intercellular Communication	Familial Mediterranean fever (FMF) is a genetic multisystem disorder of unknown etiology characterized by recurrent episodes of fever and pain due to acute inflammation of the peritoneum, synovia, or pleura.	19590876
Inflammation, Demyelination	Altered Intercellular Communication	Mitochondrial alterations might occur as a response to demyelination and inflammation, since demyelination leads to an increased energy demand in axons and could thereby affect the number, distribution and activity of mitochondria.	19591199
Inflammation, Coronary Artery Disease, Endothelial dysfunction	Altered Intercellular Communication	In conclusion, insulin resistance, endothelial dysfunction, and inflammation are important cardiovascular risk factors in coronary artery disease patients; and L-arginine seems to have anti-inflammatory and metabolic advantages in these patients.	19592054
Inflammation, Obesity	Altered Intercellular Communication	These results suggest that LOX-1 induction may be related to adipocyte metabolism, inflammation, and immune response associated with obesity.	19592055
Inflammation, Beta-cell dysfunction	Altered Intercellular Communication	Subclinical inflammation leads to insulin resistance and beta-cell dysfunction.	19592635
Inflammation, Hydronephrosis	Altered Intercellular Communication	Clinical presentation is influenced by sex, severity of inflammation and presence of hydronephrosis.	19593223
Vasculitis	Altered Intercellular Communication	Imaging studies have revealed large vessel inflammation in at least 60% of patients with GCA.	19593227
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	On liver biopsy (n = 35) 80% had evidence of inflammation, 57% had fibrosis, and 9% had steatosis.	19593250
Rheumatoid Arthritis	Altered Intercellular Communication	[MMP- and FAP-mediated non-inflammation-related destruction of cartilage and bone in rheumatoid arthritis].	19593575
Neoplasms, Synovitis, Refractory anemias, Giant Cell Tumors, Rheumatoid Arthritis	Altered Intercellular Communication	Due to morphological similarities of high-grade synovitis in rheumatoid Arthritis (RA) and mesenchymal, semimalignant tumors and the hypothesis that RA progression is not only inflammation-related, but also determined by tumor-like mechanisms, a comparison was made between expression profiles of RA, giant cell tumor of bone (GCT) and normal synovium (ND).	19593575
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Omega-3 fatty acid supplements improve the cardiovascular risk profile of subjects with metabolic syndrome, including markers of inflammation and auto-immunity.	19593941
Thyroid associated opthalmopathies, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Histological and radiological signs indicative for chronic sinus mucosal inflammation in Graves' ophthalmopathy.	19593970
Acute and chronic inflammation	Altered Intercellular Communication	A histological examination of the sinus mucosa indicative for chronic polypoid inflammation was present in 25 patients.	19593970
Eosinophilic disorder, Inflammation	Altered Intercellular Communication	Six patients had mucosal changes suggesting chronic non-polypoid inflammation with tissue eosinophilia on histological exam.	19593970
Actinomycosis, Inflammation, Neoplasms	Altered Intercellular Communication	Although rare, actinomycosis of the caecum should be taken into consideration in the differential diagnosis of tumorous lesions of the caecoascending part of the colon, particularly if the tumour is associated with inflammation.	19594073
Crohn Disease, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In ulcerative colitis and Crohn's disease, prostaglandins may be involved in the pathogenesis of inflammation, and increased expression of cyclo-oxygenase-2 (COX-2) has been detected.	19594490
Glomerulitis Assessment, Capillaritis, Interstitial inflammation	Altered Intercellular Communication	Transplant glomerulitis and interstitial inflammation were present in all 13 biopsies, and peritubular capillaritis was present in 12 of 13 biopsies, interstitial fibrosis/tubular atrophy in 13, and the thickening of the peritubular capillary (PTC) basement membrane in 11.	19594595
Pulmonary artery structure	Altered Intercellular Communication	Inflammation changes including dense plural adhesions, pulmonary artery adhesions and calcified lymph nodes were managed endoscopically.	19595235
Inflammation, Tissue Adhesions	Altered Intercellular Communication	Chronic inflammation induced adhesions is the key limiting factor for thoracoscopic lobectomy for benign diseases.	19595235
Inflammation, Atherosclerosis	Altered Intercellular Communication	Early life origins of low-grade inflammation and atherosclerosis risk in children and adolescents.	19595364
Inflammation	Altered Intercellular Communication	Our results showed that smaller birth weight is associated with chronic low-grade inflammation in children and adolescents.	19595364
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a central role in the development and progression of atherosclerosis, and inflammatory markers have been reported to predict cardiovascular events.	19595382
Inflammation	Altered Intercellular Communication	Percutaneous core needle biopsies showed differentiated pancreatic tissue with chronic inflammation and cystic transformation.	19595516
Inflammation	Altered Intercellular Communication	Thus, our data suggest, for the first time, that the delicate balance between PTK and PTP is disturbed during aging and inflammation, both of which lead to NF-kappaB activation via NIK/IKK and MAPKs.	19596065
Inflammation, ciliary vesicle, Obesity	Altered Intercellular Communication	In the general population, obesity is associated with inflammation, decreased high-density lipoprotein (HDL) cholesterol, increased low-density lipoprotein (LDL) cholesterol, and triglycerides (TGs), all risk factors for CV disease.	19596588
Inflammation, Dyslipidemias, Kidney Failure	Altered Intercellular Communication	Renal failure is associated with dyslipidemia and inflammation in normal-weight patients.	19596588
Granulomatous inflammation	Altered Intercellular Communication	The epidemiologic association with bioaerosols and the presence of granulomatous inflammation support consideration of mycobacterial antigens.	19596780
Inflammation, Atherosclerosis	Altered Intercellular Communication	The results confirm adipokines' involvement in the process of inflammation and atherosclerosis: protective and antiinflammatory adiponectin effect and proatherogenic and proinflammatory leptin function.	19597733
Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	Renal pathology revealed cellular to fibrocellular crescents in 21 out of 23 glomeruli with interstitial inflammation and fibrosis.	19601559
Inflammation	Altered Intercellular Communication	Osteopontin (OPN) is a secreted glycoprotein demonstrated to play an important role in inflammation.	19601999
Inflammation, Aspergillosis	Altered Intercellular Communication	This suggested that these T2-hyperintense lesions may be due to secondary inflammation caused by aspergillosis and not the aspergillosis itself.	19602790
palladium, Inflammation, Elastosis perforans serpiginosa	Altered Intercellular Communication	We analyzed probes from patients with normal kidney function (n = 10), with normal kidney function and inflammation (n = 10), on PD without (n = 10) and with EPS (n = 9).	19602904
palladium, Inflammation, Appendicitis, CTCAE, Elastosis perforans serpiginosa	Altered Intercellular Communication	Vasculopathy was significantly more pronounced in EPS (normal 0.4 +/- 0.5, appendicitis 0.2 +/- 0.3, PD 1.0 +/- 0.7 and EPS 1.6 +/- 1.2; p < 0.0001) than in PD or inflammation (normal 30 +/- 16, appendicitis 82 +/- 48, PD 1,936 +/- 952 and EPS 2,613 +/- 1,209; p < 0.0001), whereas the density of vessels were decreased (normal 125 +/- 114, appendicitis 817 +/- 347, PD 81 +/- 57 and EPS 36 +/- 33; p < 0.0001).	19602904
Arterial Stiffness, Inflammation, Refractory anemias	Altered Intercellular Communication	Elevated plasma OPN levels are associated with increased arterial stiffness in RA patients, suggesting that this protein might represent a bridge protein between inflammation and the consequent joint damage and cardiovascular risk in RA patients.	19603104
ARCN1 gene, Inflammation	Altered Intercellular Communication	Increased expression of the Th17-related cytokines IL-17A, IL-22 and IL-23 in COPD patients may reflect their involvement, and that of specific IL-17-producing cells, in driving the chronic inflammation seen in COPD.	19604272
Inflammation	Altered Intercellular Communication	However, iNOS activity is stimulated during inflammation by cytokines such as TNF-alpha and the amount of NO produced by iNOS may be a 1,000-fold greater than that produced by endothelial NOS.	19604438
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Correlation with clinical variables, laboratory markers of inflammation, metabolic syndrome features, adipokines and adhesion molecules was also assessed.	19604438
Inflammation	Altered Intercellular Communication	There was a minimal inflammatory backdrop consisting of lymphocytes but not plasma cells or acute inflammation.	19606014
Refractory anemias, Inflammation, ETV3 wt Allele	Altered Intercellular Communication	The prevalence and associations of the MetS in RA remain uncertain: systemic inflammation and anti-rheumatic therapy may contribute.	19607680
Inflammation	Altered Intercellular Communication	DARC-positive small vessels and capillary vessels were associated with sites of inflammation and their number was increased during episodes of acute lung rejection.	19608592
Inflammation	Altered Intercellular Communication	A common change that occurs with age in the central nervous system is an increase in microglial-associated inflammation.	19609089
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The surgical pathological findings of fibrosis and the severity of inflammation correlated with the MRI category in all cases.	19610137
Fibrosis Assessment, Gastrointestinal inflammation	Altered Intercellular Communication	The MRI categories also correlated with the presence and level of intestinal inflammation and fibrosis on surgical pathology, and may be of prognostic use in the management of CD patients.	19610137
Inflammation, Gangrene	Altered Intercellular Communication	Surgical intervention was performed with the findings of a perforated and gangrenous appendix and severe inflammation at the left side of the abdomen.	19610564
Asthma, Bronchitis	Altered Intercellular Communication	We hypothesized that c-kit and PDGF receptor inhibition may decrease bronchial inflammation and interfere with airway remodeling, which are crucial features of severe asthma.	19614621
Inflammation, Carcinogenesis	Altered Intercellular Communication	The aim was to determine whether qualitative and quantitative differences in perineoplastic inflammation in OTRs contribute to the increased carcinogenesis.	19614769
Inflammation	Altered Intercellular Communication	Considerable inflammation was observed in all intraepithelial SCC (inflammatory infiltrate depth 2.80 +/- 2.21 mm immunocompetent patients, 2.15 +/- 2.95 mm OTRs).	19614769
Immunocompetent, Inflammation	Altered Intercellular Communication	Inflammation was more pronounced in invasive SCC of immunocompetent patients (4.60 +/- 4.67 mm) and OTRs (3.30 +/- 5.90 mm) (P < 0.005).	19614769
Inflammation	Altered Intercellular Communication	Perineoplastic inflammation in intraepithelial SCC is pronounced both in immunocompetent patients and OTRs.	19614769
Inflammation	Altered Intercellular Communication	Markers of inflammation and increased serum calcium were significant predictors of increased carotid artery IMT.	19614783
Communicable Diseases	Altered Intercellular Communication	High mobility group box 1 (HMGB1), a nonhistone chromatin-associated protein, is implicated as a mediator of both infectious and non-infectious inflammatory conditions.	19616266
Diabetic Nephropathy	Altered Intercellular Communication	Which components of malnutrition-inflammation-atherosclerosis syndrome are more common in haemodialysis patients with diabetic nephropathy?	19619183
HD Term Type	Altered Intercellular Communication	Malnutrition-inflammation-atherosclerosis syndrome (MIA) in haemodialysis (HD) patients is a common clinical condition characterized by increased mortality rate.	19619183
Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis frequently coexisted with inflammation in both groups (51.5% in DM and 20.0% in non-DM) and less frequently with malnutrition.	19619183
Inflammation, Malnutrition, Demographics Domain	Altered Intercellular Communication	The frequency of inflammation was only slightly higher in DM, while of malnutrition was similar.	19619183
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Typically, they are characterized by severe and increasingly painful inflammation, often accompanied by fibrosis and constriction of the anatomic channels needed for normal life, such as the small airways of the lungs and, in the present report, the urethra.	19619201
Kidney Failure, Chronic, Inflammation, Depressed mood, Impaired	Altered Intercellular Communication	As end-stage kidney disease (ESKD) is associated with chronic inflammation, impaired immunity and depressed lymphocyte numbers, we sought to determine whether altered TRPV1 (and related TRPV2) expression in immune cells might be a contributing factor.	19619644
Inflammation, ovarian neoplasm	Altered Intercellular Communication	Serum C-reactive protein (CRP) is a widely used biomarker of inflammation and has been previously shown to be a promising biomarker in patients with ovarian cancer.	19619929
Inflammation	Altered Intercellular Communication	Very late DES thrombosis is associated with histopathological signs of inflammation and intravascular ultrasound evidence of vessel remodeling.	19620501
Necrotizing granulomatous inflammation, Histiocytes, Necrosis, Brucellosis	Altered Intercellular Communication	Histopathological examination of the mass revealed chronic granulomatous inflammation characterized by central necrosis, histiocyte and lymphocyte infiltration and formation of giant cells, compatible with brucellosis.	19621621
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic inflammation of the airways and lung parenchyma plays a major role in the pathogenesis of chronic obstructive pulmonary disease (COPD).	19622350
Inflammation, Dysplasia	Altered Intercellular Communication	The surgical specimen was a complex anastomosing inflammatory pseudopolyp 5 cm x 4 cm x 3 cm in size, with a focus of low-grade dysplasia in an area free of inflammation.	19623327
Inflammation, Myositis, CTCAE 5.0	Altered Intercellular Communication	The pathogenic role of inflammation in inclusion body myositis (IBM) remains uncertain.	19623629
Inflammation, Waldenstrom Macroglobulinemia	Altered Intercellular Communication	The predominant type of inflammation seen in the lamina propria was lymphoplasmacytic in 85.5% cases.	19624086
Cataract, Acute inflammation, Secondary glaucoma	Altered Intercellular Communication	One year later, he had uncomplicated cataract extraction but developed prolonged postoperative inflammation and secondary glaucoma.	19624348
Airway structure, ARCN1 gene	Altered Intercellular Communication	This study further suggests cineole as an active controller of airway inflammation in COPD by intervening in the pathophysiology of airway inflammation of the mucus membrane.	19624838
Granuloma, Cutaneous, Traumatic injury	Altered Intercellular Communication	Sea urchin injuries have been associated with a variety of cutaneous lesions, ranging from acute, transient reactions, to more chronic inflammatory conditions that result in the formation of granulomas.	19624987
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Metabolic syndrome (MetS) features chronic inflammation and exaggerated postprandial triacylglyceride (TAG) responses.	19625064
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	The influence of COX-2 single nucleotide polymorphisms on abdominal aortic aneurysm development and the associated inflammation.	19625268
Inflammation, Kidney Failure	Altered Intercellular Communication	Renal failure itself had such a strong prognostic impact that conventional factors such as poor myocardial function or inflammation were concealed.	19626297
Inflammation	Altered Intercellular Communication	Moreover, it is related to the epithelial-mesenchymal transition process and T cell differentiation associated with inflammation.	19626374
Inflammation	Altered Intercellular Communication	Baseline inflammation is not predictive of periprocedural troponin elevation after elective percutaneous coronary intervention.	19626398
Inflammation	Altered Intercellular Communication	Few data are available about the incidence and the relation to inflammation of troponin elevation following percutaneous coronary intervention (PCI), a potential predictor of longterm outcome.	19626398
Inflammation, myonecrosis	Altered Intercellular Communication	Baseline inflammation cannot predict onset of minor myonecrosis damage (expressed by troponin elevation) induced by PCI, a significant predictor of long-term outcome in this setting.	19626398
Nasopharyngeal Angiofibroma	Altered Intercellular Communication	Juvenile nasopharyngeal angiofibromas (JNAs) are rare benign lesions that express hormonal receptors.	19626637
Inflammation, Carcinogenesis	Altered Intercellular Communication	Chemokines are important in inflammation and in carcinogenesis.	19627345
Post-Traumatic Stress Disorder, Inflammation, Disease	Altered Intercellular Communication	Posttraumatic stress disorder (PTSD) has been associated with several somatic diseases, and low-grade inflammation may be one psychobiological mechanism mediating this relationship.	19628221
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	PTSD was diagnosed in 55 participants (1.8%), and low-grade inflammation (i.e.	19628221
Post-Traumatic Stress Disorder, Inflammation, Cardiovascular Diseases, Diabetes Mellitus	Altered Intercellular Communication	Our findings suggest a close relationship between PTSD and low-grade inflammation possibly representing one psychobiological pathway from PTSD to poor physical health, particularly with respect to cardiovascular and pulmonary disease as well as diabetes.	19628221
Diabetic Retinopathy, Inflammation	Altered Intercellular Communication	In diabetic retinopathy, the vascular endothelium is damaged due to oxidative stress and inflammation, and vitreous VEGF concentration becomes elevated.	19628492
Inflammation, Carcinoma of lung	Altered Intercellular Communication	A strong link has been recently demonstrated between inflammation and lung cancer.	19628777
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus	Altered Intercellular Communication	Associations between dietary fiber and inflammation, hepatic function, and risk of type 2 diabetes in older men: potential mechanisms for the benefits of fiber on diabetes risk.	19628814
Inflammation, Postoperative Complications	Altered Intercellular Communication	Data concerning pre- and postoperative visual acuity and intraocular pressure (IOP), lens status, macular status, location of primary break, surgical time, postoperative inflammation, peri- and postoperative complications, and number of sutured sites were collected.	19629017
Inflammation	Altered Intercellular Communication	We conclude that the fluctuations in the measured R wave are the result of waxing and waning inflammation associated with sarcoid activity.	19629665
Intestinal metaplasia, Gastritis, Atrophic	Altered Intercellular Communication	Elimination of H. pylori was associated with regression of gastric inflammation and atrophy, whereas intestinal metaplasia progressed.	19629722
Inflammation	Altered Intercellular Communication	However, inflammation of the gastric mucosa regresses after H. pylori elimination.	19629722
Pancreatitis, Acute, Inflammation	Altered Intercellular Communication	Patients with severe acute biliary pancreatitis (SABP) constitute a subgroup of severe acute pancreatitis (SAP) patients in whom systemic inflammation may be triggered and perpetuated by different mechanisms.	19630953
Inflammation, Osteoporosis, Atherosclerosis, Congenital Abnormality, Cardiovascular calcification	Altered Intercellular Communication	In this article, several possible mechanisms linking cardiovascular calcification and osteoporosis are discussed, including aging, tissue-specific responses to chronic inflammation, flow-limiting atherosclerosis of skeletal end arteries causing ischemic abnormalities in metabolism, shared endogenous regulatory factors that affect the two tissues in a reciprocal manner, and changes in a cysteine protease inhibitor, fetuin.	19631027
Intraocular inflammation	Altered Intercellular Communication	Primary outcome measures included suture, complication, and hypotony rates; logMAR visual acuity; and intraocular inflammation.	19631124
Inflammatory abnormality of the eye	Altered Intercellular Communication	The self-sealing incisions did not adversely affect the overall surgical or visual outcomes, led to faster visual rehabilitation, and reduced ocular inflammation.	19631124
Inflammation, Bone necrosis	Altered Intercellular Communication	Bisphosphonate-associated osteonecrosis of the jaw: a key role of inflammation?	19631301
Inflammation, Osteonecrosis of Jaw	Altered Intercellular Communication	The number of medullary inflammatory cells taken as an index of inflammation allowed us to discriminate two inflammation grades in the ONJ samples.	19631301
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Low-grade inflammation, characterized by marrow fibrosis and low inflammatory cells infiltration, increased numbers of TRAP(+) mono- and multineacleated cells was seen in patients with bone exposure<2 cm(2).	19631301
Inflammation, Leucocytic infiltrate, Arterial Hypervascularization	Altered Intercellular Communication	High-grade inflammation, associated with larger lesions, showed amounts of tartrate-resistant acid phosphatase(+)/calcitonin receptor(-) mono- and multinucleated cells, osteocyte apoptosis, hypervascularization and high inflammatory cell infiltration.	19631301
Bone necrosis	Altered Intercellular Communication	Taken together these data suggest that bone necrosis precedes clinical onset and is an inflammation-associated process.	19631301
Inflammation, Osteochondritis Dissecans	Altered Intercellular Communication	Considering that the inflammation plays a definite role in the pathogenesis of POCD and the vagus nerve can mediate inflammation via CAP, we hypothesize that the transcutaneous vagus nerve stimulation may attenuate POCD by decreasing inflammatory response in elderly patients.	19631475
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Peroxisome proliferator-activated receptor gamma (PPAR-gamma) has been described to have a role in the modulation of various genes involved in Abeta homeostasis, inflammation, and energy metabolism, making it a candidate gene for risk of Alzheimer's disease (AD).	19631630
Inflammation, Vascular calcification	Altered Intercellular Communication	These included genes with roles in inflammation (IL1beta, IL8, ICAM1, TNFAP3, ESM1 and CCL2), tissue remodelling (VEGF, VEGFbeta, ADM and MMP14) and vascular calcification (MGP, BMP2, SPP1, OPG and DCN).	19631729
Autoimmune Pancreatitis	Altered Intercellular Communication	IgG4-associated cholangitis is a steroid-responsive hepatobiliary inflammatory condition associated with autoimmune pancreatitis that clinically and radiologically mimics primary sclerosing cholangitis.	19633647
Inflammation, Observation Method - Coagulation, Fibrosis Assessment	Altered Intercellular Communication	We performed real-time quantitative PCR analysis of 107 genes with functional roles in inflammation, coagulation, fibrosis and apoptosis; some key genes were confirmed at a protein expression level by immunohistochemistry and correlated to the degree of morphological severity present in the individual samples analyzed.	19635508
Inflammation, Depressed mood	Altered Intercellular Communication	Relationships between measures of inflammation and autonomic function are stronger among depressed than non-depressed cardiac patients.	19635552
Inflammation	Altered Intercellular Communication	Interventions targeting regulation of both autonomic control and inflammation may be of particular importance.	19635552
Inflammation, Crohn Disease	Altered Intercellular Communication	Mural inflammation in Crohn disease: location-matched histologic validation of MR imaging features.	19635832
Inflammation, Fibrosis Assessment, Acute inflammation, Edema	Altered Intercellular Communication	Histopathologic grading of acute inflammation with the acute inflammatory score (AIS) (on the basis of mucosal ulceration, edema, and quantity and depth of neutrophilic infiltration) and the degree of fibrostenosis was performed at each site, and results were compared with MR imaging features.	19635832
Crohn Disease	Altered Intercellular Communication	Increasing mural thickness, high mural signal intensity on T2-weighted fat-saturated images, and a layered pattern of enhancement reflect histologic features of acute small-bowel inflammation in Crohn disease.	19635832
Inflammation	Altered Intercellular Communication	A threshold brightness value of percentage of increase of 46% had a sensitivity and specificity of 96% and 73%, respectively, in the prediction of moderate or severe grade for inflammation at endoscopy.	19635834
Inflammation, Leukocytosis, Trichinellosis	Altered Intercellular Communication	Laboratory results showed mild leukocytosis, inflammation, and mild liver and muscle cytolytic syndrome, all suggestive of trichinellosis.	19635890
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Acid sphingomyelinase inhibitors normalize pulmonary ceramide and inflammation in cystic fibrosis.	19635928
Eosinophilic esophagitis	Altered Intercellular Communication	Eosinophilic esophagitis (EE) is an inflammatory condition characterized by intense eosinophilic infiltration of the esophagus.	19636182
Trachoma	Altered Intercellular Communication	In Maridi, prevalence of one of the signs of active trachoma (trachomatous inflammation-follicular (TF)) in children aged 1-9 years was 0.4% (95% confidence interval (CI), 0.0%-0.8%), while no children showing the other possible sign, trachomatous inflammation-intense (TI), were identified.	19636366
Inflammation	Altered Intercellular Communication	An urgent bronchoscopy showed two prostheses in the right and one in the left main bronchus, which had caused inflammation with extensive occlusion of the bronchus.	19636518
Tissue damage, Inflammation	Altered Intercellular Communication	Extravasation of NPLD in two patients resulted in mild inflammation without tissue damage.	19636553
concomitant disease, Endotoxemia, Colitis, Ischemic	Altered Intercellular Communication	Considering the patient's concomitant disease, we postulated that ischemic colitis with cirrhosis-related intestinal inflammation and endotoxemia was the possible diagnosis in this sporadic case.	19636574
Inflammation, Urinary tract infection	Altered Intercellular Communication	Urinary trypsin inhibitor (UTI), produced in the liver, has been considered to suppress inflammation.	19636634
Acute inflammation, Urinary tract infection	Altered Intercellular Communication	The production of UTI may decrease after a hepatectomy and thereby increase the incidence of postoperative inflammation.	19636634
Inflammation, Dilated Cardiomyopathy Pathway	Altered Intercellular Communication	Atorvastatin improves endothelial function and cardiac performance in patients with dilated cardiomyopathy: the role of inflammation.	19636689
Inflammation, Endothelium, Endothelial dysfunction	Altered Intercellular Communication	Inhibition of inflammation, alleviating endothelium damage and endothelial dysfunction might comprise part of the underlying mechanisms leading to the improvement of LV function and exercise tolerance in patients with IDCM.	19636689
Cyst, Fibrosis Assessment, Interstitial inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Affected kidneys are not only characterized by the formation of cysts, but also by changes associated with the extracellular matrix and interstitial inflammation, which can progress to fibrosis and loss of renal function.	19637234
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We confirm the development of inflammation and renal fibrosis and the expression of extracellular matrix molecules including transforming growth factor were also increased in cystic kidney.	19637234
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	These results indicate that expression of proteins related with inflammation and renal fibrosis changes by Mxi1 inactivation in polycystic kidney.	19637234
Inflammation	Altered Intercellular Communication	We also measured plasma and cell-associated endotoxin and different plasma markers of inflammation.	19638210
Inflammation, Weight decreased	Altered Intercellular Communication	We are currently conducting a study to test the hypothesis that intensive weight loss will reduce inflammation and joint loads sufficiently to alter disease progression, either with or without exercise.	19638215
Traumatic, Hypopituitarism	Altered Intercellular Communication	Incomplete deficiency of hypothalamic hormones in hypothalamic hypopituitarism associated with an old traumatic brain injury.	19638713
Colorectal Carcinoma	Altered Intercellular Communication	Influence of inflammation-based prognostic score on mortality of patients undergoing chemotherapy for far advanced or recurrent unresectable colorectal cancer.	19638907
Inflammation, Edema	Altered Intercellular Communication	Thus, PRP-induced macular edema was caused by inflammation, while visual prognosis after PPV was not influenced by pretreatment of PRP.	19639332
Pain Distress Question, Neurologic Deficits, Inflammation	Altered Intercellular Communication	Clinical findings were pain due to bilateral inflammation of the lumbar nerve roots, fistulised cold abcess and motor deficit in both lower extremities.	19639843
Inflammation, Heart failure, Necrosis	Altered Intercellular Communication	Short term effects of milrinone on biomarkers of necrosis, apoptosis, and inflammation in patients with severe heart failure.	19640280
Inflammation, Myocardial Infarction	Altered Intercellular Communication	Whether biomarkers of myocardial necrosis, inflammation and apoptosis change in response to acute milrinone administration is not well established.	19640280
Inflammation, Aortic Aneurysm, Abdominal, atherosclerotic	Altered Intercellular Communication	The influence of total plasma homocysteine and traditional atherosclerotic risk factors on degree of abdominal aortic aneurysm tissue inflammation.	19640909
Aneurysm, Inflammation	Altered Intercellular Communication	Aneurysm specimens were obtained from 89 male patients aged 52 to 83 years, underwent asymptomatic not ruptured AAA (mean diameter 5.5 cm) open repair and graded for degree of histologic inflammation.	19640909
Acute respiratory failure, Inflammation	Altered Intercellular Communication	Current cigarette smoking, odds ratio (OR) 4.4, 95% confidence interval 1.3 to 15.2, P = .01 and no other ARF, neither tHcy levels OR 0.9 (0.9-1.02), P = .2 were associated with high-grade tissue inflammation.	19640909
Inflammatory abnormality of the eye, Ocular Cicatricial Pemphigoid	Altered Intercellular Communication	T-helper 17 lymphocytes (Th17) were identified in the healthy conjunctiva and in patients with ocular cicatricial pemphigoid (OCP), a disease characterized by chronic ocular surface inflammation.	19641634
Inflammation, Hypertensive (finding), Metabolic Syndrome X	Altered Intercellular Communication	Despite experimental data that demonstrates that angiotensin receptor antagonists reduce cellular oxidant stress and inflammation, olmesartan was not different than amlodipine in changing ox-NEFA and inflammatory markers in hypertensive subjects with the metabolic syndrome.	19641984
Inflammation, Conjunctivitis, Keratoconjunctivitis Sicca	Altered Intercellular Communication	After the termination of the treatment, the signs of the clinical inflammation of the conjunctival inflammation subsided but the KCS problems remained.	19642357
Inflammation, Skin Diseases, Infectious, Necrotizing fasciitis	Altered Intercellular Communication	Necrotizing fasciitis is an uncommon but serious infection of skin, subcutaneous fat and fascia, characterised by rapidly spreading inflammation and associated with considerable morbidity and mortality.	19642531
Infarction, Thrombus, Inflammation, Cerebral Atherosclerosis	Altered Intercellular Communication	In conclusion, the MCP-1 level as well as hsCRP in the blood can be a potential predictive marker of recurrent thrombotic brain infarction, and may reflect inflammation that promotes intracranial large-artery atherosclerosis.	19642908
Small bowel bacterial overgrowth syndrome, Inflammation, Intestines, Small, Affection	Altered Intercellular Communication	SIBO rate was also higher in patients with affection of both the colon and small bowel, while inflammation of the (neo)terminal ileum again showed only tendential association with the development of SIBO.	19643023
Inflammation, Respiratory Failure, Critical Illness	Altered Intercellular Communication	C-reactive protein (CRP), a biomarker of inflammation, has predicted mortality in end-stage respiratory failure and in the critically ill patients.	19643829
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Sputum and lung function were periodically assessed in stable moderate chronic obstructive pulmonary disease (COPD) outpatients to determine relationships between bronchial colonisation and inflammation.	19643939
ARCN1 gene, Haemophilus parainfluenzae, Conization, Bronchitis	Altered Intercellular Communication	A load-related relationship to bronchial inflammation in moderate COPD was observed for colonisation by H. influenzae, but not for colonisation by H. parainfluenzae.	19643939
Inflammation, Atherosclerosis	Altered Intercellular Communication	Peroxisome proliferator-activated receptor (PPAR) activation reduces inflammation and atherosclerosis, but recent evidence raised concerns about its beneficial clinical effects.	19644041
Inflammation, Heart failure, Carotid Intima-Media Thickness	Altered Intercellular Communication	Carotid intima-media thickness, systemic inflammation, and incidence of heart failure hospitalizations.	19644052
Inflammation, hyperthermia treatment, Ischemic stroke, Cerebrovascular accident	Altered Intercellular Communication	Severity of stroke and inflammation are important determinants of hyperthermia after ischemic stroke.	19644066
Inflammation, Electrocardiogram: myocardial infarction (finding), Cerebrovascular accident	Altered Intercellular Communication	High-sensitivity C-reactive protein (hsCRP) and lipoprotein-associated phospholipase A2 (Lp-PLA2) are hypothesized to be biomarkers of systemic inflammation and risk of myocardial infarction (MI) and stroke.	19644070
Inflammation, Phlegmonous gastritis	Altered Intercellular Communication	Gastric biopsy showed suppurative inflammation in the submucosal region, prompting the diagnosis of phlegmonous gastritis.	19644358
Idiopathic disease, Granulomatosis with polyangiitis	Altered Intercellular Communication	Wegener's granulomatosis (WG) is a rare idiopathic disease in which small and medium-sized arteries are affected by necrotizing granulomatous inflammation.	19644426
Inflammation, Kidney Failure, Acute, Fever, CTCAE	Altered Intercellular Communication	The patient developed acute renal failure, and also had fever and unilateral ear inflammation.	19644613
Refractory anemias, Inflammation, Arthritis, ASF1A gene	Altered Intercellular Communication	Gamma/delta T cells were antigen independently stimulated by inflammation at affected joints and produced enhanced amounts of IL-17 to exacerbate arthritis in mice with CIA but not in SKG mice with arthritis or patients with RA.	19644886
Inflammation, Rheumatoid Arthritis, Depression, CTCAE, Pain Distress Question	Altered Intercellular Communication	Depression, inflammation, and pain in patients with rheumatoid arthritis.	19644894
Inflammation, Depression, CTCAE	Altered Intercellular Communication	An association between depression and inflammation has been suggested.	19644894
Inflammation, Pain Distress Question, Refractory anemias, Rheumatoid Arthritis, Depression, CTCAE	Altered Intercellular Communication	In patients with rheumatoid arthritis (RA), pain is a major symptom associated with depression and inflammation.	19644894
Refractory anemias, Inflammation, Depression, CTCAE, Pain Distress Question	Altered Intercellular Communication	We examined the independent associations between depression, the inflammation marker C-reactive protein (CRP) level, and pain in patients with RA.	19644894
Inflammation, Depression, CTCAE, Pain Distress Question	Altered Intercellular Communication	Depression severity and inflammation were associated with each other and appeared to have independent effects on perceived pain.	19644894
Inflammation, Atherosclerosis	Altered Intercellular Communication	The antioxidant capacity of normal high-density lipoproteins (HDLs) is lost during inflammation, and these dysfunctional HDLs might predispose individuals to atherosclerosis.	19644959
Cardiomyopathy, Familial Idiopathic, Inflammation	Altered Intercellular Communication	These data suggest there is presence of inflammation in IDCM patients with AF.	19645035
Lesion, Inflammation	Altered Intercellular Communication	Obviously, the inflammation in AD lesions neutralizes the expected induction of hCAP18 and even induces suppression.	19645825
Airway structure, ARCN1 gene	Altered Intercellular Communication	Airway inflammation and anti-protease defences rapidly improve during treatment of an acute exacerbation of COPD.	19645868
Airway structure, ARCN1 gene	Altered Intercellular Communication	There are few data on the short-term natural history of airway inflammation during severe episodes of acute exacerbation of COPD (AECOPD).	19645868
Inflammation	Altered Intercellular Communication	Conventional treatment for severe AECOPD is associated with rapid reduction of neutrophilic inflammation and improvement in anti-protease defences.	19645868
Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Current research has focused upon the potential links between novel markers of vascular risk such as endothelial dysfunction, oxidative stress, inflammation and insulin resistance in the pathogenesis of Type 2 diabetes and its complications.	19646193
Inflammation, Hypoglycemia, diabetic	Altered Intercellular Communication	GSE significantly improved markers of inflammation and glycaemia and a sole marker of oxidative stress in obese Type 2 diabetic subjects at high risk of cardiovascular events over a 4-week period, which suggests it may have a therapeutic role in decreasing cardiovascular risk.	19646193
Inflammation, Hypertensive (finding), Periodontal Diseases	Altered Intercellular Communication	The conjoint detrimental effect of chronic periodontal disease and systemic inflammation on asymmetric dimethyl-arginine in untreated hypertensive subjects.	19646696
Periodontal Diseases, Inflammation, Hypertension, CTCAE, Endothelial dysfunction	Altered Intercellular Communication	To investigate the relationship between periodontal disease indexes (PDI) and endothelial dysfunction by means of asymmetric dimethyl-arginine (ADMA) in conditions of both increased and decreased systemic inflammation in the setting of hypertension.	19646696
Inflammation, Antihypertensive Agents	Altered Intercellular Communication	PDI are associated in a dose-dependent manner with ADMA in untreated hypertensives and increased systemic inflammation further contributes to that phenomenon.	19646696
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Impact of type 2 diabetes mellitus on diffuse inflammatory activation of de novo atheromatous lesions: implications for systemic inflammation.	19646908
Inflammation, Demographics Domain, Diabetes Mellitus	Altered Intercellular Communication	Local coronary and systemic inflammation is pronounced in patients with diabetes mellitus (DM).	19646908
Inflammation, Demographics Domain	Altered Intercellular Communication	We investigated whether or not, in patients with DM, thermal heterogeneity of culprit lesions (CLs) correlates with that of non-culprit lesions (NCLs) and with systemic inflammation.	19646908
Inflammation, Demographics Domain	Altered Intercellular Communication	In patients with DM, local inflammatory activation is diffuse and correlates with systemic inflammation.	19646908
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	In chronic kidney disease the contribution of decreased glomerular filtration rate (GFR) versus enhanced inflammation to cause insulin resistance (IR) is controversial.	19648735
HD Term Type, Malnutrition, Inflammation	Altered Intercellular Communication	Malnutrition is common in HD patients, it is associated with inflammation and contributes to the high incidence of cardiovascular (CV) disease in this setting (malnutrition-inflammation-atherosclerosis syndrome).	19648737
Inflammation, Malnutrition	Altered Intercellular Communication	Hence, the plasma BNP level was found to be associated with malnutrition but not with inflammation.	19648737
Klinefelter Syndrome	Altered Intercellular Communication	Hormonal profile suggested primary hypogonadism and cytogenetics report suggested a karyotype, 47, XXY, in all counted cells, consistent with the diagnosis of Klinefelter syndrome.	19651018
Crohn Disease, Acute inflammation	Altered Intercellular Communication	Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease.	19652016
palladium, Psychiatry Specialty	Altered Intercellular Communication	These results provide novel in vivo evidence for a role of the cholinergic neurotransmission in psychiatric comorbidity of PD.	19652126
Inflammation, Hemorrhage, Obstruction, S100A4 protein, human	Altered Intercellular Communication	It may become clinically evident when complicated by pathological changes such as inflammation, bleeding, obstruction, and malignant transformation.	19653355
Inflammation, beta Thalassemia	Altered Intercellular Communication	Soluble endothelial adhesion molecules and inflammation markers in patients with beta-thalassemia intermedia.	19654073
Inflammation, beta Thalassemia	Altered Intercellular Communication	These findings support the hypothesis that a serious degree of endothelial activation and damage along with a state of chronic inflammation underlie the pathophysiology of beta-thalassemia intermedia.	19654073
Inflammation, Hypopyon	Altered Intercellular Communication	Significantly more severe anterior chamber inflammation in terms of anterior chamber cells (P=0.006) and hypopyon formation (P=0.034) was observed with higher frequency of AU attacks (P=0.007) in the HLA-B27 positive group than in the HLA-B27 negative group.	19654959
Unknown (origin) (qualifier value), Inflammation	Altered Intercellular Communication	In conclusion, despite more severe inflammation and a higher recurrence rate, HLA-B27 positive AU shows similar good final ocular and visual outcomes compared to HLA-B27 negative, idiopathic AU in a Korean population.	19654959
Inflammation	Altered Intercellular Communication	GCF MMP-8 levels increased with periodontal inflammation.	19656031
Inflammation, Chronic disease	Altered Intercellular Communication	Physical activity has recently been established as a potential modifier of the inflammatory process, suggesting that it mitigates inflammation and consequently reduces the incidence of several chronic diseases such as cardiovascular events.	19657301
Inflammation	Altered Intercellular Communication	These data indicate that beyond leisure time, work and transportation physical activity may reduce inflammation.	19657301
Inflammation, CD55 gene, Cerebrovascular accident	Altered Intercellular Communication	The inflammation marker Hp carried as much additional predictive information value on AMI and stroke as TC.	19657769
Inflammation, agep	Altered Intercellular Communication	Because TNF-alpha stimulated inflammation and also p53-related apoptosis occurs in AGEP, a TNF-alpha blocking agent such as etanercept may be effective for quick treatment.	19657917
Hypercalcemia, CTCAE, Inflammatory abnormality of the eye, Malignant Neoplasms	Altered Intercellular Communication	Zoledronic acid is the most effective treatment in patients with hypercalcemia secondary to malignancy; occasionally it can be related to ocular inflammation.	19657981
Choroiditis	Altered Intercellular Communication	CFs are probably a sign of severe choroidal inflammation and associated with corticosteroid resistance and/or dependence, which indicates IMT.	19657984
Inflammation	Altered Intercellular Communication	Abnormalities of ciliary structure are the cause of abnormalities in mucociliary clearance and chronic inflammation consecutively.	19658359
Ear Inflammation, Bronchiectasis, Bronchitis, Pneumonia	Altered Intercellular Communication	The boy aged 13 years with clinical manifestations (chronic rhinorrhea, sinuitis, recurrent otitis media, recurrent bronchial inflammation, pneumonia and finally bronchiectasis) has been presented.	19658359
vascular inflammations, Diabetic Angiopathies	Altered Intercellular Communication	Diabetic vascular complications are associated with vascular inflammation.	19659775
Inflammation	Altered Intercellular Communication	In all 11 specimens, immunohistochemical investigations showed a perifollicular and subepidermal inflammation of CD-3-, CD-4-, CD-68-, CD-79- and CD-8-cells, the latter with a striking selective epitheliotropism.	19659829
Phrynoderma, Inflammation, Rupture	Altered Intercellular Communication	To conclude, we could show follicular hyperkeratosis and lymphocytic perifollicular inflammation as early patterns in pathogenesis, whereas rupture of the follicle structure takes place later.	19659829
Sjogrens Syndrome", Thymic Carcinoma, Inappropriate ADH Syndrome	Altered Intercellular Communication	Thymic carcinoma associated with Sjogren's syndrome and syndrome of inappropriate antidiuretic hormone.	19660250
Inflammation, Kidney Failure, Endothelial dysfunction, Obesity	Altered Intercellular Communication	Increasing evidence suggests that both obesity and renal insufficiency are associated with increased systemic inflammation, thrombogenicity, and endothelial dysfunction.	19660351
Inflammation, Corneal edema	Altered Intercellular Communication	Anterior chamber inflammation and microhyphema, IOP, and corneal edema.	19660735
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Minor elevations in CRP (>3 mg/L) are a nonspecific marker of systemic inflammation and predict the future onset of cardiovascular disease.	19661186
Inflammation, Drug toxicity, Necrosis	Altered Intercellular Communication	Biopsy showed sinusoidal congestion, necrosis of hepatocytes, inflammation, and hepatocyte drop out around the hepatic venule consistent with drug toxicity.	19662540
Hypoalbuminemia	Altered Intercellular Communication	Discussions whether hypoalbuminemia is just a marker for the malnutrition-inflammation syndrome as well as for the increased morbidity and mortality of those patients or is it an etiological factor, are becoming more and more intense.	19662779
Inflammation, Granulation finding	Altered Intercellular Communication	Bone trabeculae and bone units were replaced by interrupted bone fragments, which were surrounded by inflammation and granulation tissue and few osteocytes were seen in bone lacunae in the experimental group.	19662974
Inflammation, Congenital heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	To study the inflammation response and the biocompatibility of valved bovine jugular vein conduit (BJVC) and valved bovine jugular vein patch (VBJV-P) in treating complex congenital heart disease (CHD).	19662998
Inflammation, Atherosclerosis	Altered Intercellular Communication	Chronic immune inflammation underlying pathogenesis of PA contributes to development of early atherosclerosis and its complications.	19663192
PROS1 gene, Inflammation, Cardiovascular morbidity	Altered Intercellular Communication	Reduced HRV reflects sympatho-vagal imbalance in PsA patients associated with the disease duration and activity, smoking, femoral IMT, markers of inflammation (CRP) in males; with standard cardiovascular risk factors, fibrinogen, CRP, carotid IMT in women, and may be identified as a risk factor for cardiovascular morbidity and mortality in further studies.	19663193
Inflammation	Altered Intercellular Communication	This is closely related with the activity of systemic inflammation.	19663195
Inflammation	Altered Intercellular Communication	MMP-2 can be regarded as an important marker of inflammation as MMP-9 in the pathogenesis of AMI.	19664397
Inflammation, Whipple Disease	Altered Intercellular Communication	Reduced numbers of duodenal lymphocytes, increased numbers of CD163(+) and stabilin-1(+), reduced numbers of inducible nitric synthase+ duodenal macrophages, and increased percentages of CD163(+) peripheral monocytes indicated a lack of inflammation and a M2/alternatively activated macrophage phenotype in Whipple's disease.	19664628
Inflammation, Whipple Disease	Altered Intercellular Communication	The lack of excessive local inflammation and alternative activation of macrophages, triggered in part by the agent T whipplei itself, may explain the hallmark of Whipple's disease: invasion of the intestinal mucosa with macrophages incompetent to degrade T whipplei.	19664628
Retinal Detachment, Inflammation	Altered Intercellular Communication	Exudative retinal detachment and active intraocular inflammation were significantly associated with poorer VA in the sympathizing eye.	19665105
Retinal Detachment, Inflammation	Altered Intercellular Communication	The presence of an exudative retinal detachment and active intraocular inflammation correlated with poorer vision in the sympathizing eye.	19665105
Inflammation, Anxiety, CTCAE 3.0, Pain Distress Question	Altered Intercellular Communication	Early neonatal inflammation affects adult pain reactivity and anxiety related traits in mice: genetic background counts.	19665540
Pain Distress Question, Inflammation	Altered Intercellular Communication	Protracted or recurrent pain and inflammation in the early neonatal period may cause long-lasting changes in central neural function.	19665540
Inflammation, Anxiety, CTCAE 3.0, Pain Distress Question	Altered Intercellular Communication	(1) to study whether timing of postnatal exposure to persistent inflammation alters responsiveness to thermal pain in the adult animal; (2) to assess whether animals experiencing early postnatal chronic inflammation display altered anxiety related behavior; (3) to study the importance of genetic background.	19665540
Anxiety, CTCAE 3.0, Inflammation	Altered Intercellular Communication	Adult mice, CD1 and B6C3F1, displayed low anxiety traits only if they had been exposed to persistent inflammation on PND1 and not on PND14.	19665540
Inflammation, Pain Distress Question	Altered Intercellular Communication	Our research suggests a role for genetic background in modulating long-term behavioral consequences of neonatal persistent inflammation: the data support the hypothesis that pain experienced very early in life differentially affects adult behavioral and emotional responsiveness in outbred (CD1) and hybrid mice (B6C3F1).	19665540
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Inflammation is an important element in the development and destabilization of atherosclerotic plaque.	19665935
Obesity	Altered Intercellular Communication	Obesity is considered a chronic low-grade inflammatory status and the stromal vascular fraction (SVF) cells of adipose tissue (AT) are considered a source of inflammation-related molecules.	19666003
Inflammation, Obesity	Altered Intercellular Communication	It now appears that obesity is associated with a low-grade inflammation of white adipose tissue resulting from chronic activation of the innate immune system as interleukin-1 beta (IL-1).	19666082
Acromegaly	Altered Intercellular Communication	Hormonal alterations in acromegaly stimulates adenomatose polyps development making that increase it prevalence.	19666287
Inflammation, Bile Duct Stenosis, Bile Ducts, Extrahepatic, Jaundice, Obstructive	Altered Intercellular Communication	Recurrence of inflammation in the extrahepatic bile duct can lead to bile duct stenosis, obstructive jaundice and cavernous transformation of the portal vein.	19666415
Necrosis of retina, Choroiditis	Altered Intercellular Communication	Histological examination of retinal tissue identified numerous round-to-elliptical toxoplasmic cysts within the retina, with retinal necrosis and minimal choroidal inflammation.	19666926
Primary malignant neoplasm, Toxic effect, Palmar-plantar erythrodysesthesia syndrome, Leukopenia, Inflammatory disease of mucous membrane, Thrombocytopenia	Altered Intercellular Communication	To identify genetic markers in the pharmacokinetic and pharmacodynamic pathways of sunitinib that predispose for development of toxicities: thrombocytopenia, leukopenia, mucosal inflammation, hand-foot syndrome, and any toxicity according to National Cancer Institute Common Toxicity Criteria higher than grade 2.	19667267
Inflammation, Palmar-plantar erythrodysesthesia syndrome	Altered Intercellular Communication	The risk for mucosal inflammation was increased in the presence of the G allele in CYP1A1 2455A/G (OR, 4.03; P = .021) and the prevalence of hand-foot syndrome was increased when a copy of TTT in the ABCB1 (3435C/T, 1236C/T, 2677G/T) haplotype (OR, 2.56; P = .035) was present.	19667267
Migraine Disorders, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	In migraine therapy, beta-blockers are well established as effective agents for prophylaxis, and beta-blockers may reduce levels of C-reactive protein, a sensitive marker of inflammation in cardiovascular disease.	19667668
Inflammation, Malnutrition	Altered Intercellular Communication	[Can FT3 levels facilitate the detection of inflammation or catabolism and malnutrition in dialysis patients?].	19668301
Inflammation, Malnutrition	Altered Intercellular Communication	A reduction in thyroid function in dialysis patients could be a marker of malnutrition and/or inflammation.	19668301
Inflammation, Malnutrition, Syndrome	Altered Intercellular Communication	Our aim has been to evaluate the incidence of low T3 syndrome in a group of dialysis patients and analyze its relationship with different parameters of malnutrition and inflammation.	19668301
Inflammation, Malnutrition	Altered Intercellular Communication	Low FT3 levels are correlated bioquimical and anthropometric parameters indicators of malnutrition and inflammation.	19668301
Communicable Diseases, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation and infection do not promote arterial aging and cardiovascular disease risk factors among lean horticulturalists.	19668697
Inflammation	Altered Intercellular Communication	Here we characterize health and aging among the Tsimane, Amazonian forager-horticulturalists with short life expectancy, high infectious loads and inflammation, but low adiposity and robust physical fitness.	19668697
Inflammation, Hypertension, CTCAE, Atherosclerosis	Altered Intercellular Communication	Inflammation has been implicated in all stages of arterial aging, atherogenesis and hypertension, and so we test whether greater inflammation associates with atherosclerosis and CVD risk.	19668697
Communicable Diseases, Inflammation	Altered Intercellular Communication	Markers of infection and inflammation were much higher among Tsimane than among U.S. adults, whereas HDL was substantially lower.	19668697
Communicable Diseases, Inflammation	Altered Intercellular Communication	Regression models examine associations of ABI and BP with biomarkers of energy balance and metabolism and of inflammation and infection.	19668697
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Arteriovascular degeneration	Altered Intercellular Communication	Inflammation may not always be a risk factor for arterial degeneration and CVD, but instead may be offset by other factors: healthy metabolism, active lifestyle, favorable body mass, lean diet, low blood lipids and cardiorespiratory health.	19668697
Vasculitis	Altered Intercellular Communication	It is defined as inflammation of skin blood vessel walls.	19669086
Communicable Diseases, Inflammation	Altered Intercellular Communication	In group 1 inflammation occurred in 25 cases (5.3%) and an infection in 32 cases (6.8%).	19669706
Inflammation, Infection	Altered Intercellular Communication	In group 2 there were 37 cases of inflammation (5.5%) and 13 infections (2.0%).	19669706
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	In CKD patients, TC and AVG insertion result in a transient state of inflammation 1 week post-operatively, which is not observed after AVF surgery.	19670170
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Inflammation in benign prostatic hyperplasia: a 282 patients' immunohistochemical analysis.	19670242
Large prostate, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	Prostatic inflammation could be a key component in prostate enlargement and benign prostatic hyperplasia (BPH) progression.	19670242
Inflammation	Altered Intercellular Communication	Our aim was to characterize inflammatory cells infiltrate within BPH tissue and to correlate inflammation and clinical data.	19670242
Inflammation	Altered Intercellular Communication	Inflammation score was defined by combining six cytological parameters and five markers on immunohistochemistry (IHC).	19670242
prostatitis	Altered Intercellular Communication	IPSS score (21 vs. 12; P = 0.02) and prostate volume (77 cm(3) vs. 62 cm(3); P = 0.002) were significantly higher in patients with high-grade prostatic inflammation.	19670242
Inflammation	Altered Intercellular Communication	The role of inflammation in BPH development was highlighted by the strong correlation between histological inflammation, IPSS, and prostate volume.	19670242
Inflammation	Altered Intercellular Communication	Therefore, inflammation is a therapeutic target for BPH.	19670242
Weakness	Altered Intercellular Communication	The changes raise the possibility that TP may cause weakness through impairment of distal neural transmission.	19670323
Inflammation, Calcinosis, Coronary heart disease, Heart failure	Altered Intercellular Communication	In both groups, patients with HVC were older than HVC-free ones, more of them had coronary heart disease, cardiac insufficiency, aortic calcinosis, and biochemically identifiable inflammation.	19670713
Inflammation, Overactive Bladder	Altered Intercellular Communication	[Blood lymphocytes and mast cells of the detrusor as diagnostic markers of overactive urinary bladder and its immune inflammation].	19670813
Inflammation, Respiratory failure without hypercapnia	Altered Intercellular Communication	Comparison of two non-bronchoscopic methods for evaluating inflammation in patients with acute hypoxaemic respiratory failure.	19671148
Pneumonitis, Respiratory failure without hypercapnia	Altered Intercellular Communication	However, there are no data comparing non-bronchoscopic bronchoalveolar lavage (mini-BAL) and s-Cath for assessing lung inflammation in acute hypoxaemic respiratory failure.	19671148
Inflammation	Altered Intercellular Communication	When the protein concentration in the lung was high, the s-Cath was a more sensitive method; by contrast, as inflammation increased, both methods provided similar estimates of neutrophil percentages in the lung.	19671148
Inflammation, Opportunistic Infections, Lesion of cervix, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	Cervical exfoliated cell specimens were collected from 301 randomly selected women accepting opportunistic screening for cervical lesions with the cytological results and hybrid capture 2 (HC-2) assay>or=atypical squamous cells of uncertain significance (ASC-US), 48 with the pathological diagnosis>or=cervical intraepithelial neoplasia (CIN)2 (case group) and 253 with normal histological result or only inflammation (control group), aged (34+/-9) (21-59).	19671291
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	These results indicate that high s-7KCHO is closely associated with the progression of coronary atherosclerosis and inflammation.	19672027
Inflammation, Gangrene, Appendix Perforation, CTCAE	Altered Intercellular Communication	PCT is potentially increased in rare cases of severe inflammation and, in particular, after appendiceal perforation or gangrenous appendicitis.	19672084
Inflammation, Comorbidity	Altered Intercellular Communication	Predictive characteristics included: age, sex, Charlson comorbidity score, biliary tract inflammation, hospital teaching status, and admission type.	19672665
Inflammation, Tropical Disease	Altered Intercellular Communication	A corneal penetration secondary to inflammation or chronic trophic disease is an emergency situation in ophthalmology.	19672808
Vitritis, Inflammation	Altered Intercellular Communication	After reduction of systemic drugs, the exacerbation of local inflammation and vitritis was observed.	19673441
Inflammation, Wheezing	Altered Intercellular Communication	Polymorphisms in inflammation genes, tobacco smoke and furred pets and wheeze in children.	19674346
Airway structure	Altered Intercellular Communication	Persistent wheeze in childhood is associated with airway inflammation.	19674346
Inflammation, Wheezing	Altered Intercellular Communication	Polymorphisms in inflammation genes might affect the association between environmental exposures and risk of recurrent wheeze in early childhood.	19674346
Granulomatous inflammation	Altered Intercellular Communication	Three histopathologic patterns were discovered: granulomatous inflammation (2 cases), plasma cell-rich pyogenic granuloma-like pattern (1 case), and reactive fibroinflammatory pattern (6 cases).	19674728
Inflammation, Inflammatory abnormality of the eye	Altered Intercellular Communication	Acyclovir caused a dramatic improvement in the chronic or recurrent ocular inflammation in all instances, with an average duration of improvement of inflammation of 15.3 months.	19674728
Inflammation	Altered Intercellular Communication	Non-infected hemodialysis catheters are associated with increased inflammation compared to arteriovenous fistulas.	19675528
Communicable Diseases, Inflammation	Altered Intercellular Communication	Although hemodialysis catheters predispose to infection which, in turn, causes inflammation, we studied whether they induce inflammation independent of infection.	19675528
Communicable Diseases, Inflammation	Altered Intercellular Communication	Our study shows that catheters might contribute to increased inflammation independent of infection, and supports avoidance of catheters and a timely conversion to fistulas with catheter removal.	19675528
diabetic	Altered Intercellular Communication	Hormonal environment of diabetic patients is believed to be an important contributing factor in this regard.	19676082
Inflammation, Tooth structure	Altered Intercellular Communication	A 24-month recall showed no evidence of periodontal inflammation and no adverse symptoms, and the treated tooth exhibited good healing and normal function.	19678457
Refractory anemias, Inflammation, destruction joint	Altered Intercellular Communication	Altered or chronic activation of proto-oncogenic Ras family GTPases is thought to contribute to inflammation and joint destruction in RA, and abrogation of Ras family signaling is therapeutic in animal models of RA.	19678938
Inflammation, Gastrointestinal Stromal Sarcoma	Altered Intercellular Communication	The molecular and cellular mechanisms linking chronic inflammation and gastrointestinal malignancy are not known with certainty.	19679052
Inflammation, Aortic valve disorder, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	The assumption that the pathogenesis of aortic valve disease is similar to that of atherosclerosis has not been supported by recent studies; rather there has been increasing evidence of a pathogenetic role of inflammation and endothelial dysfunction.	19679278
Communicable Diseases, Necrotizing vasculitis, Inflammation, Meningovascular syphilis	Altered Intercellular Communication	Laboratory findings were suggestive of prior spirochetal infection, and autopsy revealed necrotizing vasculitis and extensive adventitial inflammation involving the basilar and vertebral arteries, supporting the diagnosis of meningovascular syphilis.	19680027
Inflammation, Uveitis	Altered Intercellular Communication	The preoperative complications resolved in all cases, with the inflammation settling postoperatively in the patients with preoperative uveitis and no patients developing tube or plate exposure at last follow-up.	19680058
Demyelination, Multiple Sclerosis, Meningitis	Altered Intercellular Communication	Meningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosis.	19680141
Meningitis	Altered Intercellular Communication	Quantitative analysis revealed significant meningeal inflammation in chronic MS patients; T cells were the predominant inflammatory cells.	19680141
Demyelination, Meningitis	Altered Intercellular Communication	Morphometric analysis was performed on coronal hemisphere sections of the MS cases to assess subpial demyelination; no correlation between the extent of subpial demyelination and extent of meningeal inflammation was identified.	19680141
Meningitis	Altered Intercellular Communication	Our data suggest that the occurrence of cortical lesions is not related to the presence of meningeal inflammation in a large number of chronic MS patients.	19680141
Obesity	Altered Intercellular Communication	These results provide evidences of an existing relationship between HVEM and obesity, which suggest that this TNF superfamily receptor could be involved in the pathogenesis of obesity and inflammation-related activity.	19680232
Keratitis	Altered Intercellular Communication	In two patients with initial graft rejection and vascularization, subconjunctival and perilimbal application of bevacizumab was beneficial in overcoming the corneal inflammation and initial rejection.	19680676
Inflammation, Obesity	Altered Intercellular Communication	Although it is produced mainly in the liver, its recently described expression in adipose tissue has been shown to be enhanced in massive obesity due to chronic low-grade inflammation.	19681654
hepcidin	Altered Intercellular Communication	We suggest that acute inflammatory changes could affect the regulation of hepcidin expression in subcutaneous adipose tissue and thus possibly contribute to inflammation-induced systemic changes of iron metabolism.	19681654
Cholestasis, Pruritus, Fatigue	Altered Intercellular Communication	Some studies suggest that certain clinical symptoms of cholestasis, such as fatigue and pruritus, result from altered neurotransmission.	19681778
Respiration Disorders, IgE-mediated food allergy, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The pathology underlying allergic respiratory diseases is considered to be IgE-mediated type I allergy characterized by mucosal inflammation that occurs in response to allergen exposure.	19681921
Follicle, Inflammation, Communicable Diseases	Altered Intercellular Communication	The primary event is a follicular occlusion with secondary inflammation, infection and destruction of the pilo-sebaceo-apocrine apparatus and extension to the adjacent sub-cutaneous tissue.	19682181
Cessation of life, Inflammation, incident	Altered Intercellular Communication	Circulating biomarkers of inflammation and hemostasis are associated with incident MI/CHD death but not incident angina uncomplicated by MI or CHD death in older men.	19682232
Inflammation, Hyperhomocysteinemia	Altered Intercellular Communication	Matrix degradation and inflammation may be involved in this link between hyperhomocysteinaemia and CVD.	19682403
Inflammation, Thrombosis	Altered Intercellular Communication	Inflammation and thrombosis biomarkers and incident frailty in postmenopausal women.	19682668
methyldopa, Age related macular degeneration	Altered Intercellular Communication	Inflammation probably plays a major role in the pathogenesis of age-related macular degeneration (AMD).	19684010
Inflammation	Altered Intercellular Communication	In GCA and chronic inflammation most monocytes and lymphocytes expressed GR (88.9%).	19684157
Inflammation	Altered Intercellular Communication	The presence of CD68-positive cells and the extent of GR-staining in chronic inflammation are suitable to predict complete remission in GCA.	19684157
Rheumatoid Arthritis, Temporomandibular Joint	Altered Intercellular Communication	Endogenous glutamate in association with inflammatory and hormonal factors modulates bone tissue resorption of the temporomandibular joint in patients with early rheumatoid arthritis.	19686927
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Associations of long- and short-term air pollution exposure with markers of inflammation and coagulation in a population sample.	19687019
Orthodontic, Inflammation	Altered Intercellular Communication	Insertion of fixed orthodontic appliances can induce an increase in oral biofilm and thereby cause inflammation of the periodontal tissues.	19687149
Inflammation	Altered Intercellular Communication	Panniculitides encompass various clinical syndromes characterized by inflammation of the fibrous septae, fatty lobules, or both components of the subcutaneous tissue.	19687423
Inflammation, Narcolepsy	Altered Intercellular Communication	To test this hypothesis, we evaluated the remaining hypocretin cells in human narcolepsy brains for the presence of aggregated protein inclusions, gliosis, and inflammation.	19687452
Inflammation	Altered Intercellular Communication	The lack of increased markers of inflammation also argues against a progressive and continuous neurodegenerative process.	19687452
Inflammation, Arthritis	Altered Intercellular Communication	Leptin is an adipokine regulating energy balance, and it has recently been related also to arthritis and inflammation as a proinflammatory factor.	19688109
Neurogenic Inflammation, Fibromyalgia, Urticaria, Neuropathy	Altered Intercellular Communication	Chronic urticaria may thus be viewed in many patients, as a consequence of fibromyalgia syndrome; in fact, skin neuropathy (fibromyalgia syndrome) may trigger neurogenic skin inflammation (chronic urticaria).	19688152
APP gene, Inflammation, Aortic Aneurysm, Abdominal, Endothelial dysfunction	Altered Intercellular Communication	The etiology of abdominal aortic aneurysm (AAA) includes inflammation and endothelial dysfunction.	19689995
Inflammation, Ototoxicity	Altered Intercellular Communication	Whereas factors responsible for disease initiation affect striatal subregions differently, those factors contributing to disease progression affect all striatal subregions to a similar degree and may therefore reflect non-specific mechanisms such as oxidative stress, inflammation or excitotoxicity.	19690093
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	In addition, liver biopsy was analyzed for steatosis, inflammation and fibrosis.	19690397
Inflammation, Fibrosis Assessment, Bronchiolitis	Altered Intercellular Communication	Compared to controls, patients with UIP, NSIP and CB presented increased bronchiolar inflammation, peribronchiolar inflammation and fibrosis and decreased luminal areas.	19690403
Orbital Pseudotumor	Altered Intercellular Communication	Idiopathic sclerosing orbital inflammation--a case series study.	19690442
Gliosis, Inflammation, Spongiosis, Necrosis, Pathologic Neovascularization	Altered Intercellular Communication	The second phase (n=14 patients) was subdivided into: (a) a phase of acute inflammation (3-37 days after onset) (n=5 patients), where we observed especially features of acute inflammation together with coagulative necrosis, and (b) phase of chronic inflammation (10 days-53 years after the onset) (n=9 patients), in which prevail mononuclear and macrophage infiltrate, astrogliosis, spongiosis and neo-vascularization.	19690757
Inflammation, Helicobacter pylori, Primary malignant neoplasm, Communicable Diseases, Ulceration, CTCAE	Altered Intercellular Communication	Helicobacter pylori (H. pylori) infection up-regulates the expression of matrix metalloproteinases (MMPs), which may be involved in chronic inflammation, ulceration, and even cancer development.	19690958
Inflammation, Fibrosis Assessment, Weight decreased, Fatty degeneration	Altered Intercellular Communication	The combination of weight loss and antioxidant drugs to ameliorate insulin resistance and improve steatosis, inflammation and fibrosis provides the rational for therapeutic trials.	19691668
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	On between-group comparison, Viusid was found to be associated with a significantly greater improvement in steatosis (P < 0.001), ballooning (P = 0.002) and lobular inflammation (P = 0.025), but not in fibrosis (P = 0.07).	19691668
Inflammation, Non-alcoholic Fatty Liver Disease, Fatty degeneration	Altered Intercellular Communication	Our results indicate that treatment with diet and exercise leads to a notable improvement in the histological features of NAFLD; however, the administration of Viusid intensifies the improvements of histological findings, especially of steatosis and inflammation.	19691668
Inflammation, Helicobacter pylori	Altered Intercellular Communication	Histological examinations of biopsy specimens taken from the giant folds showed signs of chronic inflammation, and Helicobacter pylori was also identified.	19691800
HD Term Type, Inflammation, Overhydration	Altered Intercellular Communication	Inflammation, overhydration and elevated cardiac biomarkers are related to outcome in haemodialysis (HD) patients.	19692417
HD Term Type, Inflammation	Altered Intercellular Communication	Here, we explored the relationship between the body composition (BC), inflammation and cardiac biomarker concentrations in HD patients longitudinally.	19692417
Inflammation, Malnutrition, Overhydration	Altered Intercellular Communication	Moreover, cTnT, BNP, NT-proBNP and hsCRP were significantly related, showing a complex relation between overhydration, malnutrition, inflammation and cardiac biomarkers in dialysis patients.	19692417
Inflammation, Rhabdomyolysis	Altered Intercellular Communication	Clinical and echographic evaluations were diagnostic of pectoral inflammation suggesting rhabdomyolysis.	19692835
Inflammation, Neurocysticercosis	Altered Intercellular Communication	The association of host age and gender with inflammation around neurocysticercosis cysts.	19695154
Granuloma, Pneumonitis, Pulmonary Fibrosis	Altered Intercellular Communication	Pathological examinations of patients' lung tissue displayed nonspecific pulmonary inflammation, pulmonary fibrosis and foreign-body granulomas of pleura.	19696157
Dry Eye Syndromes, Conjunctivitis	Altered Intercellular Communication	Confocal scanning laser microscopy was an efficient and a noninvasive tool for the quantitative assessment of the conjunctival inflammation and epithelial cell densities as well as evaluation of conjunctival morphologic alterations, such as microcysts in patients with SSDE and NSSDE dry eye disease.	19696170
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Involvement of platelet coagulation and inflammation in the endothelium of Schlemm's canal.	19696181
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	To investigate whether the endothelial cells of Schlemm's canal (ECSCs) are connected to lymphatic vessels or are involved in platelet coagulation and inflammation, by comparing them to lung tissue cells.	19696181
Inflammation	Altered Intercellular Communication	ECSCs and EACLs are suggested to have developed specifically for their functions from the aspects of the anti-platelet coagulation system and may be involved in inflammation for leukocyte infiltration.	19696181
Hashimoto Disease, Inflammation, Thyroiditis	Altered Intercellular Communication	The histologic diagnosis of lymphocytic (Hashimoto) thyroiditis requires lymphocytic inflammation of the thyroid gland in combination with Hourthle cell metaplasia of follicular epithelial cells.	19696577
Inflammation, Hurthle cell metaplasia of thyroid gland	Altered Intercellular Communication	The degree of lymphocytic inflammation of the thyroid gland was graded on a scale of 0 to 3 (0 = no inflammation, 1 = mild inflammation, 2-3 moderate-to-marked inflammation with Hourthle cell metaplasia).	19696577
Arterial Stiffness, Inflammation, Hypertension, CTCAE, Hyperuricemia	Altered Intercellular Communication	It is suggested that the combination of olmesartan and azelnidipine has advantages over the combination of olmesartan and a thiazide with respect to avoiding hyperuricemia, sympathetic activation, renin-angiotensin-aldosterone system stimulation, inflammation, oxidative stress, and increased arterial stiffness in patients with moderate hypertension.	19696778
Inflammation	Altered Intercellular Communication	Acute inflammation in horizontal incompletely impacted third molar with radiolucency in the elderly.	19696898
Inflammation	Altered Intercellular Communication	The odds ratio of severe acute inflammation exhibited in men aged more than 61 years compared to men aged 41-50 years was 16.67 (95% CI: 1.76-158.27; P < 0.01).	19696898
Inflammation	Altered Intercellular Communication	These odds ratios indicate an association of acute pericoronitis, including the severe forms of acute inflammation that result from pericoronitis, with pericoronal radiolucency below the crown in the elderly.	19696898
Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Balloon Dilatation, Fatty Liver Disease	Altered Intercellular Communication	NAFLD was classified as simple steatosis, type 1 nonalcoholic steatohepatitis (NASH), characterized by ballooning degeneration and perisinusoidal fibrosis, or type 2 NASH, characterized by portal inflammation and portal fibrosis.	19697129
Thrombosis	Altered Intercellular Communication	The white blood cell count and its differential are established inflammation-sensitive biomarkers with a proven prognostic value in the field of atherothrombosis.	19697588
Necrotizing granulomatous inflammation, Adenolymphoma, Facial paralysis	Altered Intercellular Communication	Fine needle aspiration cytology and diagnostic pitfalls in Warthin's tumor with necrotizing granulomatous inflammation and facial nerve paralysis: a case report.	19697730
Inflammation, Necrosis	Altered Intercellular Communication	Cytologic examination showed acute, chronic and granulomatous inflammation and rare squamous cells in a background of finely granular necrotic debris.	19697730
Necrotizing granulomatous inflammation, Inflammation, Fibrosis Assessment, Squamous metaplasia	Altered Intercellular Communication	Histologic examination of the excised mass revealed a WT with extensive necrotizing granulomatous inflammation, with acute and chronic inflammation, fibrosis and squamous metaplasia.	19697730
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Chronic inflammation is a characteristic of Alzheimer's disease (AD).	19698145
Inflammation, Data types - Address	Altered Intercellular Communication	Thus, inflammation facilitates the onset of sporadic AD.	19698145
HD Term Type, Inflammation	Altered Intercellular Communication	Increased sCD14 level is related positively to markers of inflammation and negatively to nutritional status and is an independent predictor of mortality in long-term HD patients.	19699018
vascular inflammations	Altered Intercellular Communication	Specifically, markers of vascular inflammation and oxidative stress might be helpful in the determination of clinical outcomes.	19699337
Inflammation, Atherosclerosis	Altered Intercellular Communication	Our study results demonstrated that neutrophils and monocytes which play an important role in inflammation and atherosclerosis were independently related with SUA.	19699626
Inflammation	Altered Intercellular Communication	There was no relationship between sACE2 activity and markers of systemic inflammation.	19700132
Inflammation	Altered Intercellular Communication	Secondhand smoke (SHS) exposure is associated with circulating markers of inflammation and endothelial function in adult men and women.	19700161
Intraocular inflammation	Altered Intercellular Communication	There were no serious adverse events and no identifiable intraocular inflammation.	19700196
Inflammatory abnormality of the eye	Altered Intercellular Communication	Intravitreal injection of up to 4 mg of VEGF Trap-Eye in patients with NVAMD was well tolerated with no evidence of ocular inflammation.	19700196
Acute Lung Injury, Inflammation, Observation Method - Coagulation, Disease	Altered Intercellular Communication	Coagulation and fibrinolysis abnormalities are observed in acute lung injury (ALI) in both human disease and animal models and may contribute to ongoing inflammation in the lung.	19700643
Inflammation, Lung cyst	Altered Intercellular Communication	The triterpenoid CDDO limits inflammation in preclinical models of cystic fibrosis lung disease.	19700644
Inflammation, Fibrosis Assessment, Lung	Altered Intercellular Communication	Excessive inflammation in cystic fibrosis (CF) lung disease is a contributor to progressive pulmonary decline.	19700644
Obesity Hypoventilation Syndrome, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Endothelial dysfunction and specific inflammation in obesity hypoventilation syndrome.	19701463
Hypoventilation, Inflammation, Endothelial dysfunction, Obesity	Altered Intercellular Communication	What moderate chronic hypoventilation adds to obesity on systemic inflammation and endothelial dysfunction remains unknown.	19701463
Intraocular inflammation, Retinal Vasculitis	Altered Intercellular Communication	Multiple yellowish spots appeared in the deep retina without evidence of intraocular inflammation or retinal vasculitis.	19702067
Traumatic injury, Fibromatosis, Aggressive	Altered Intercellular Communication	The etiology of desmoid tumors are uncertain but may be related to operation, trauma or hormonal factors.	19702071
Intraocular inflammation	Altered Intercellular Communication	Frequency and clinical features of intraocular inflammation in Tokyo.	19702710
Intraocular inflammation, Uveitis	Altered Intercellular Communication	To investigate frequencies and clinical features of intraocular inflammation (uveitis) in Tokyo, Japan.	19702710
Communicable Diseases	Altered Intercellular Communication	It is important for emergency physicians to be aware of the classic and most common risk factors leading to this illness, including genetic and acquired prothrombotic states, infection, inflammatory conditions, and certain drugs.	19703742
Inflammation	Altered Intercellular Communication	We have recently described a novel population of natural regulatory T cells (T(reg)) that are characterized by the expression of HLA-G and may be found at sites of tissue inflammation (HLA-G(pos) T(reg)).	19705413
Inflammation, Hemorrhage	Altered Intercellular Communication	Maximal bladder capacity was negatively correlated with inflammation, mast cell count, haemorrhages and the overall cystoscopic aspect.	19707951
Inflammatory Bowel Diseases, Crohn Disease, Inflammation	Altered Intercellular Communication	Crohn's disease is a chronic inflammatory bowel disease characterized by discontinuous chronic inflammation that may affect virtually all organs, including the head and neck.	19708494
Inflammation, Ischemic stroke	Altered Intercellular Communication	Accumulating evidence suggests that inflammation plays an important role in the acute phase of ischemic stroke.	19709661
Inflammation, Fibrosis Assessment, Edema	Altered Intercellular Communication	CMR markers for oedema, inflammation and fibrosis defined myocardial involvement.	19710029
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Early enhancement images were quantified for inflammation, as was regional fibrosis in late enhancement images.	19710029
Inflammation, Atrophic	Altered Intercellular Communication	A histological analysis showed that cagA status was associated with inflammation and atrophy both in the antrum and in the corpus, while homB status was associated with inflammation and atrophy in the corpus.	19710266
helium, Hepatic Encephalopathy, Abnormal behavior, Chronic liver disease	Altered Intercellular Communication	Hepatic encephalopathy (HE) in chronic liver disease is characterized by neuropsychiatric and motor disturbances and associated with a net increase of inhibitory neurotransmission.	19710544
helium, Abnormal behavior	Altered Intercellular Communication	Our data suggest that neurotransmitter alterations are probably not the primary key factor responsible for the neuropsychiatric and motor disturbances associated with HE.	19710544
Inflammation, Fibrosis Assessment, MULTISYSTEM DISORDER	Altered Intercellular Communication	Cystic fibrosis (CF) is a multisystem disorder intrinsically associated with inflammation of mucosal surfaces.	19710558
Inflammation, Ileal Obstruction, distal ileal obstruction syndrome, Ileitis, neuromuscular function	Altered Intercellular Communication	Because inflammation can result in enteric neuromuscular dysfunction we hypothesized that terminal ileitis in patients with CF may predispose to distal ileal obstruction syndrome (DIOS).	19710558
Inflammation, distal ileal obstruction syndrome	Altered Intercellular Communication	Lymphocyte-predominant mucosal and transmural ileal inflammation was present in 6 of 6 patients with DIOS.	19710558
Inflammation	Altered Intercellular Communication	Submucosal or transmural lymphocyte predominant inflammation was also present in 6 of 6 infants with complicated MI, which, when coupled with submucosal myofibroblast proliferation (5/6), appeared highly predictive of CF rather than non-CF atresia.	19710558
Inflammation, distal ileal obstruction syndrome	Altered Intercellular Communication	Submucosal or transmural inflammation of the ileum is common in newborns with CF and MI and older children with DIOS.	19710558
Pain Distress Question, Inflammation, Blepharoptosis	Altered Intercellular Communication	A nine-year-old girl presented with pain, unilateral ptosis, inflammation of the upper eyelid and restricted ocular motility.	19710967
Inflammation	Altered Intercellular Communication	Three years after salmonellosis, PI-FGID patients showed no evidence of inflammation in the gastric or colonic mucosa, but visceral sensitivity and anxiety/somatization levels were increased.	19711225
Esophagitis	Altered Intercellular Communication	The eosinophilic oesophagitis is a rare allergy-like inflammation of the oesophagus especially seen in young men with increasing incidence.	19711290
Inflammation, Dysplasia	Altered Intercellular Communication	The feasibility of autofluorescence spectroscopy to detect subtle alterations in tissue architecture and biochemical composition induced by dysplasia and inflammation has been studied in the field of oral oncology.	19712020
Inflammation, Kidney Failure, Cardiovascular Diseases	Altered Intercellular Communication	Further studies are needed to test other genetic determinants of the association between systemic inflammation and cardiovascular disease in renal failure patients.	19712260
Pituitary Adenoma, Pituitary Diseases, Hyperprolactinemia	Altered Intercellular Communication	Magnetic resonance imaging revealed a pituitary adenoma, and laboratory tests corroborated the hyperprolactinaemia without other hormonal pituitary abnormalities.	19712547
vascular inflammations, Thrombosis	Altered Intercellular Communication	Our findings showed that the Mediterranean diet influences expression of key genes involved in vascular inflammation, foam cell formation and thrombosis.	19712933
Inflammation, Calcinosis, Cardiac Hypertrophy	Altered Intercellular Communication	Patients with all three calcification risk factors, namely inflammation, high CaxP, and no RRF, showed the highest prevalence of valvular calcification and had the most severe cardiac hypertrophy.	19713292
palladium, Cardiac Hypertrophy, Inflammation	Altered Intercellular Communication	The association among loss of RRF, valvular calcification, and cardiac hypertrophy was closely linked to increased inflammation and high Ca x P in PD patients.	19713292
Inflammation, AAVS1 gene, Vasculitis, CTCAE, Disease remission	Altered Intercellular Communication	Numbers of circulating CD4+ effector memory T cells are proportionally increased in patients with proteinase 3 antineutrophil cytoplasmic antibody-associated vasculitis (AAV) whose disease is in remission and are decreased during active disease, which presumably reflects their migration toward sites of inflammation.	19714581
Inflammation	Altered Intercellular Communication	Moreover, a negative correlation was observed between percentages of circulating and urine CD4+ effector memory T cells, consistent with their migration toward sites of inflammation.	19714581
Refractory anemias, Inflammation	Altered Intercellular Communication	Our data suggest that enhanced expression of IL-7Ralpha and IL-7 in RA patients contributes significantly to the joint inflammation by activating T cells, B cells, and macrophages.	19714586
Inflammatory, Inflammation, Spondylitis	Altered Intercellular Communication	Magnetic resonance imaging assessment of spinal inflammation in ankylosing spondylitis: standard clinical protocols may omit inflammatory lesions in thoracic vertebrae.	19714609
Inflammation, Spondylitis	Altered Intercellular Communication	Radiologic assessment of spinal inflammation in patients with ankylosing spondylitis (AS) relies primarily on magnetic resonance imaging (MRI), although little is known about the distribution of inflammatory lesions within the structures of the spine.	19714609
Inflammation	Altered Intercellular Communication	Inflammation was present in 263 (45%) of 588 thoracic and 86 (35%) of 245 lumbar vertebrae; the mean number of affected thoracic and lumbar vertebrae per patient were 5.4 and 1.8, respectively.	19714609
Inflammation	Altered Intercellular Communication	Inflammation was present in the lateral aspect of 219 (37%) of 588 thoracic vertebrae and 45 (18%) of 245 lumbar vertebrae (P < 0.001).	19714609
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	These findings further indicate potential regulatory functions of adipokines in intestinal inflammation that are partly gender-dependent and that may even be associated with the distinct immunopathogenesis of UC and CD.	19714754
Asthma	Altered Intercellular Communication	Depletion of antioxidants through consumption of a low antioxidant diet has been reported to increase neutrophilic airway inflammation and worsen symptoms of asthma.	19715394
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Greater posttransplant inflammation and oxidation are associated with worsening kidney function in patients with pretransplant diabetes mellitus.	19715851
Inflammation	Altered Intercellular Communication	Patients on dialysis display increased inflammation (IF) and oxidative stress (OS).	19715851
Inflammation, Atherosclerosis	Altered Intercellular Communication	At present, inflammation is considered to be one of the key players in the development and maintenance of atherosclerosis, with ample impact on renal transplant outcomes.	19715970
Inflammation, Pulmonary Embolism, pulmonary edema interstitial, Pulmonary Emphysema, Lung Diseases, Interstitial, Embolism, Infectious Lung Disorder	Altered Intercellular Communication	Type B (18 cases) occurred in pulmonary embolism; type C was found in case of inflammation of small respiratory airways (five cases); emphysema was typical for type D (nine cases); increased perfusion was observed in the parenchyma preserved from emphysema or preserved from embolism in cases of emphysema or pulmonary embolism; type F occurred in pulmonary interstitial edema (four cases) both with pulmonary infection; finally type G was found in interstitial lung diseases (five cases).	19717260
Inflammation, Endothelial dysfunction, diabetic, Atherosclerosis	Altered Intercellular Communication	Endothelial dysfunction is a common feature in type-2 diabetic patients and is associated with inflammation, increased levels of circulating soluble adhesion molecules and atherosclerosis.	19717975
Inflammation, Mental deterioration	Altered Intercellular Communication	Intensive oral hygiene care can persistently improve oral inflammation status and could slow periodontal deterioration.	19718402
Inflammation, Acute chest pain	Altered Intercellular Communication	PTX3 is a new biomarker related to inflammation that, independently of BNP, strongly predicts long-term all-cause mortality in patients with acute chest pain.	19718477
Inflammation, Idiopathic Pulmonary Fibrosis, Pneumonia, Idiopathic Interstitial Pneumonias, Fibrosis Assessment, CARD16 gene, Nonspecific interstitial pneumonia, Pneumonia, Interstitial	Altered Intercellular Communication	Idiopathic interstitial pneumonias (IIPs) comprises a group of diffuse parenchymal lung diseases of unknown etiology with varying degrees of inflammation and fibrosis including cryptogenic organizing pneumonia (COP), idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).	19721293
Inflammation, Idiopathic Interstitial Pneumonias	Altered Intercellular Communication	Systemic inflammation in the lung with IIPs might be associated with tenascin-C.	19721293
Inflammation, Idiopathic Interstitial Pneumonias	Altered Intercellular Communication	These results suggest that tenascin-C is responsible for the pathogenesis of IIPs especially via inflammation, and that it might serve as a serum marker of COP.	19721293
Inflammation, Retinitis Pigmentosa, polychondritis, Systemic disease	Altered Intercellular Communication	Relapsing polychondritis (RP) is a rare multisystemic disease characterized by the recurrent inflammation of the cartilaginous structures of the external ear, nose, joint, larynx, and tracheobronchial tree, whose etiology might involve an immunological mechanism.	19721348
Tuberculosis	Altered Intercellular Communication	[Tubercular inflammation of cervical lymph nodes with a colliquative tuberculosis focus--a case study].	19722149
Gingivitis	Altered Intercellular Communication	However, its presence during the pathogenesis of gingival inflammation has not been established in vivo.	19722795
Inflammation	Altered Intercellular Communication	Depleted tissue concentrations of Ang-1 may allow gingival inflammation to become more severe because VEGF and ET-1 secretion become less inhibited.	19722795
Inflammation, Alveolar Bone Loss	Altered Intercellular Communication	A 12-year-old child was referred to our clinic for gingival inflammation, extensive alveolar bone loss, and tooth mobility.	19722808
Parkinson Disease, Inflammation, palladium	Altered Intercellular Communication	The protein identities reflect the heterogeneity of Parkinson's disease, and thus may provide the capability of monitoring the blood for a diverse range of PD pathophysiological mechanisms: cellular degeneration, oxidative stress, inflammation, and transport.	19723509
Inflammation, Obesity, muscle mass	Altered Intercellular Communication	How obesity, muscle mass, inflammation, hormonal and lipid status, oxidative stress, antioxidant capacity and physical activity influences insulin sensitivity (IS) in frail elderly subjects remains uncertain.	19723576
Inflammation, Obesity, muscle mass	Altered Intercellular Communication	How obesity, muscle mass, inflammation, hormonal and lipid status, oxidative stress, antioxidant capacity and physical activity influences insulin sensitivity (IS) in frail elderly subjects remains uncertain.	19723576
Cessation of life, Inflammation	Altered Intercellular Communication	Age, male sex, markers of inflammation, and cognitive function were related to multiple causes of death.	19723772
Cessation of life, Inflammation	Altered Intercellular Communication	Inflammation may represent a common pathway to all causes of death.	19723772
Inflammation, Endophthalmitis, CTCAE, Glaucoma, CTCAE	Altered Intercellular Communication	Complications can occur and require frequent follow-up to monitor and treat glaucoma progression, endophthalmitis, and inflammation.	19724214
Inflammation, Dysplasia	Altered Intercellular Communication	In fact, long-standing inflammation could be directly responsible for the development of pancellular dysplasia involving epithelial, goblet, Paneth and neuroendocrine cells.	19725156
Inflammation, prostatitis	Altered Intercellular Communication	Aggressiveness of inflammation in histological prostatitis--correlation with total and free prostate specific antigen levels in men with biochemical criteria for prostate biopsy.	19725275
Inflammation, prostatitis	Altered Intercellular Communication	Although prostatitis can contribute to the lack of prostate specific antigen (tPSA) specificity, there is disagreement concerning the effect of histological inflammation on free PSA (fPSA).	19725275
Inflammation, Aggressive behavior, Prostate carcinoma	Altered Intercellular Communication	We investigated the correlation between aggressiveness of histological inflammation and tPSA, fPSA and f/tPSA in patients without detectable prostate cancer (PC).	19725275
Inflammation, Fibrosis Assessment, Stenosis, Leakage of bile	Altered Intercellular Communication	The axial nature of the blood supply to the extrahepatic ducts and the tendency of bile itself to cause rapid collagen turnover and fibrosis, combined with the inflammation and subsequent fibrosis to the surrounding tissues caused by bile leakage, give the bile ducts a high propensity for stricture formation.	19725297
Liver Abscess, Inflammation, Hepatic Infarction, Neoplasms	Altered Intercellular Communication	Microscopically, the tumor consisted of hepatic infarction, degenerated Glisson's sheath, and chronic inflammation, and chronic liver abscess was diagnosed.	19725434
Inflammation, Biceps tendinitis	Altered Intercellular Communication	Biceps tendinitis is inflammation of the tendon around the long head of the biceps muscle.	19725488
Biceps tendinitis	Altered Intercellular Communication	Inflammation of the biceps tendon in the bicipital groove, which is known as primary biceps tendinitis, occurs in 5 percent of patients with biceps tendinitis.	19725488
Cataract, Inflammation, Retinal thickening	Altered Intercellular Communication	BF suppressed anterior chamber inflammation and increasing retinal thickening after cataract surgery in patients with NPDR.	19725815
Granulomatous inflammation	Altered Intercellular Communication	Subsequent open lung biopsy revealed marked granulomatous inflammation with diagnostic Reed-Sternberg cells.	19727013
Inflammation, Neoplasms	Altered Intercellular Communication	Secondary endpoints were change in cleaved caspase-3 (CC3, apoptosis), MRI tumor volume, and serum C-reactive protein (CRP, inflammation).	19728082
Inflammation	Altered Intercellular Communication	This may be caused by a consecutive therapy associated inflammation.	19728194
Airway structure	Altered Intercellular Communication	Vitamin A and carotenoids are dietary antioxidants that are likely to play an important role against airway inflammation.	19728208
Hemorrhagic, Inflammation, Papilledema	Altered Intercellular Communication	Other frequent findings at the back of the eye are hemorrhagic nerve fibers, cotton-like exudates, papilla edema, macular star and glassy inflammation.	19728239
Communicable Diseases, Acute inflammation	Altered Intercellular Communication	Toxic Anterior Segment Syndrome is a sterile postoperative inflammation due to any non infectious substance that reaches the anterior segment during surgery.	19728242
Inflammation, Data types - Address, Agitation	Altered Intercellular Communication	The increased IL-1beta and decreased NKCA with the progress of agitation in AD suggest that inflammation produces agitation and aggravates AD.	19728317
Traumatic injury, Malignant Neoplasms	Altered Intercellular Communication	Indications for the CT scans included malignancy, inflammatory conditions and blunt trauma.	19729157
Hypercholesterolemia, atherosclerotic	Altered Intercellular Communication	Pitavastatin significantly reduced the elevated plasma levels of PTX3 in patients with hypercholesterolemia by its pleiotropic effect against atherosclerotic inflammation.	19729861
Inflammation, diabetic	Altered Intercellular Communication	Pitavastatin improved serum lipid profiles and reduced serum hsCRP levels in type 2 diabetic patients with relatively low inflammation.	19729863
Inflammation, Atherosclerosis	Altered Intercellular Communication	Since inflammation is an important contributor to atherosclerosis, gene variants mediating inflammation are of interest.	19729864
Intraocular inflammation	Altered Intercellular Communication	Mild to moderate intraocular inflammation was detected in 7 eyes.	19729985
Gastrointestinal inflammation	Altered Intercellular Communication	Recent studies suggest potential roles of the endocannabinoid system in gastrointestinal inflammation.	19730730
Inflammatory Bowel Diseases	Altered Intercellular Communication	Endocannabinoids signaling pathway, through CB(2) receptor, may reduce colitis-associated inflammation suggesting a potential drugable target for the treatment of inflammatory bowel diseases.	19730730
Cessation of life, Hernia, acute diverticulitis	Altered Intercellular Communication	Death was caused by intestinal herniation through a defect created by the greater omentum that had adhered to an area of acute serosal inflammation associated with underlying acute diverticulitis of the jejunum.	19733337
Inflammation	Altered Intercellular Communication	sCD14 and endotoxin, together with other markers of inflammation and protein-energy wasting.	19733948
Inflammation	Altered Intercellular Communication	sCD14 level is associated with inflammation and protein-energy wasting in hemodialysis patients.	19733948
Refractory anemias, Inflammation	Altered Intercellular Communication	We hypothesized that the inhibitory FcgammaRIIb inhibits TLR responses on monocyte-derived dendritic cells (DC) and serves as a counterregulatory mechanism to dampen inflammation, and we surmised that this mechanism might be defective in RA.	19734236
Arterial Stiffness, Rheumatoid Arthritis	Altered Intercellular Communication	Etanercept improves inflammation-associated arterial stiffness in rheumatoid arthritis.	19734293
Arterial Stiffness, Inflammation, Refractory anemias	Altered Intercellular Communication	Systemic inflammation (CRP) is an independent predictor of arterial stiffness and pulse wave reflection in patients with RA.	19734293
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	Laboratory tests presented normal acute phase reactants of inflammation as well as the rheumatoid factor, CK, and negative results for antinuclear, anti-DNA, anti-SSA/Ro, and anti-CCP (ELISA) antibodies.	19734739
Inflammation, Atherosclerosis	Altered Intercellular Communication	Studies have linked smoking to inflammation, platelet activation and enhanced atherosclerosis.	19734779
Interstitial inflammation, Kidney Diseases	Altered Intercellular Communication	Within the BK nephropathy group, samples with tubular basement membrane stain had more infected tubular epithelial cells (12.1+/-7.6% vs 4.4+/-5.0%, P=0.03) and a trend toward higher interstitial inflammation scores.	19734851
Inflammation	Altered Intercellular Communication	Chronic inflammation and exogenous insulin usage increases serum syndecan-1 level.	19735958
Inflammation, Malnutrition, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	The aim of this study was to look for correlation between the markers for malnutrition and inflammation, and atherosclerosis in predialysis chronic kidney disease (CKD) patients.	19736479
Inflammation	Altered Intercellular Communication	Highly sensitive C-reactive protein (hsCRP) was assayed as a marker of chronic inflammation.	19736479
Inflammation, Malnutrition	Altered Intercellular Communication	Our results indicate that a high degree of inflammation and malnutrition exists in predialysis patients as seen by high CRP values and low serum albumin levels.	19736479
Inflammation, Hernia	Altered Intercellular Communication	Despite small differences in outcome and length of hospitalisation between Amyand types, appendix inflammation, pre-operative blood examinations and hernia localisation, only right lower quadrant peritonism as a presenting sign (p=0.004) and age greater than 90 years old (p=0.04) were significantly associated with a poor outcome.	19736884
Airway structure, ARCN1 gene	Altered Intercellular Communication	We identify some Gc-insensitive cytokines, including GM-CSF, G-CSF and IL-8, that may be involved in the progression of airway inflammation in COPD patients.	19737233
Inflammation	Altered Intercellular Communication	In vitro studies suggested that nitrite may play a cytoprotective role in inflammation.	19737619
Inflammation	Altered Intercellular Communication	Regular aerobic exercise improves FMD in sHT patients, and changes of lipids and inflammation during the exercise period may partially contribute to the improvement of endothelial function.	19737872
Adenocarcinoma of colon	Altered Intercellular Communication	Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma.	19737943
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Systemic inflammation and disease progression in Alzheimer disease.	19738171
Inflammation, Tumor necrosis	Altered Intercellular Communication	Acute and chronic systemic inflammation are characterized by the systemic production of the proinflammatory cytokine tumor necrosis factor alpha (TNF-alpha) that plays a role in immune to brain communication.	19738171
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Previous preclinical research shows that acute systemic inflammation contributes to an exacerbation of neurodegeneration by activation of primed microglial cells.	19738171
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	To determine whether acute episodes of systemic inflammation associated with increased TNF-alpha would be associated with long-term cognitive decline in a prospective cohort study of subjects with Alzheimer disease.	19738171
Inflammation, Tumor necrosis, Impaired cognition, "Alzheimers Disease	Altered Intercellular Communication	Both acute and chronic systemic inflammation, associated with increases in serum tumor necrosis factor alpha, is associated with an increase in cognitive decline in Alzheimer disease.	19738171
Inflammation, Neoplasms, Necrosis	Altered Intercellular Communication	Transcatheter arterial embolization (TAE) destroys a tumor by the induction of necrosis and/or apoptosis and causes inflammation with cytokine production, which may favor immune activation and presentation of tumor-specific antigens.	19739081
Inflammation	Altered Intercellular Communication	Non-diagnostic pathology results were classified into three groups: (i) atypical cells, (ii) non-specific inflammation and (iii) inadequate specimen.	19740264
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	In two patients (3.8%) the lesions reported as non-specific inflammation were eventually confirmed as malignancies.	19740264
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Here, we show that Wrn mutant mice also develop premature liver sinusoidal endothelial defenestration along with inflammation and metabolic syndrome.	19741171
Alkalosis, Respiratory	Altered Intercellular Communication	The current leading hypotheses are that respiratory alkalosis produces an as yet unidentified change in neural excitability or that inflammatory mediators potentiate excitatory synaptic transmission.	19743470
Epithelial hyperplasia, Inflammation	Altered Intercellular Communication	Nine out of the 63 patients presented with oral clinical lesions, however, most of them presented with unspecific chronic inflammation and typical epithelial hyperplasia.	19743619
Pleurisy	Altered Intercellular Communication	No patients had signs of peritoneal or pleural inflammation as the possible cause of CA-125 rise.	19744744
Pain Distress Question, Inflammation, Edema, Lipodermatosclerosis, Hyperpigmentation	Altered Intercellular Communication	The main outcome measure was venous clinical severity scores (pain, oedema, inflammation, hyperpigmentation and lipodermatosclerosis).	19744867
Pain Distress Question, Inflammation, Edema	Altered Intercellular Communication	The mean venous clinical severity scores measured before and after 180 days were as follows: Surgery group - pain: before 1.97 standard deviation (SD) 0.19, 180 days 0.72 SD 0.53; oedema: before 1.66 SD 0.48, 180 days 0.55 SD 0.63; inflammation: before 1.55 SD 0.63, 180 days 0.72 SD 0.45.	19744867
Pain Distress Question, Inflammation, Edema	Altered Intercellular Communication	Foam sclerotherapy group - pain: before 1.81 SD 0.40, 180 days 0.56 SD 0.51; oedema: before 1.70 SD 0.47, 180 days 0.48 SD 0.64; inflammation: before 1.67 SD 0.68, after 0.89 SD 0.32.	19744867
Primary malignant neoplasm	Altered Intercellular Communication	Substantial evidence supports an association between chronic infections/inflammation, and cancer.	19745222
Inflammation, Fibrosis Assessment, Nesidioblastosis, Acinar Cell	Altered Intercellular Communication	Histopathologic specimens from the pancreas were evaluated for presence and severity of fibrosis, acinar cell atrophy, inflammation, and nesidioblastosis by a surgical pathologist blinded to clinical information.	19745778
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Hematoxylin and eosin (H&E)-stained slides were semiquantitated for evidence of necrosis, myocytolysis, interstitial fibrosis, replacement fibrosis, and the presence of inflammation.	19747852
Weight decreased, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	The relationship between the insulin-like growth factor-1 axis, weight loss, an inflammation-based score and survival in patients with inoperable non-small cell lung cancer.	19748165
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	In summary, the results of this study suggest that anabolism (IGF-1 axis) does not play a significant role in the relationship between nutritional and functional decline, systemic inflammation and poor survival in patients with inoperable NSCLC.	19748165
Aneurysm, Inflammation	Altered Intercellular Communication	Abdominal computed tomography showed a 3.8 cm wide aneurysm of the distal part of the aorta with inflammation.	19748223
Vasculitis of large artery, Inflammation	Altered Intercellular Communication	Therefore, WG should be included in the work-up of large-vessel vasculitis, which can give rise to periaortic inflammation.	19748223
Inflammation, Obesity	Altered Intercellular Communication	Normal weight obesity: relationship with lipids, glycaemic status, liver enzymes and inflammation.	19748248
Inflammation, Obesity	Altered Intercellular Communication	Normal weight obesity (NWO) is defined as an excessive body fat associated with a normal body mass index (BMI) and has been associated with early inflammation, but its relationship with cardiovascular risk factors await investigation.	19748248
Inflammation, Sarcomatoid Features, Carcinoma	Altered Intercellular Communication	Microscopically these proliferations were characterized by foci of inflammation or plexiform or solid epithelial proliferations, one of which showed a focus of carcinoma in situ, adenomatoid differentiation and another osteodentin deposits.	19748290
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Only colonies with adjacent tissue reaction (inflammation, fibrosis) were analyzed.	19748292
Panuveitis, Inflammatory abnormality of the eye, Scleritis, Uveitis, Anterior uveitis	Altered Intercellular Communication	Among 384 patients (639 eyes) observed from the point of addition of methotrexate to an anti-inflammatory regimen, 32.8%, 9.9%, 21.4%, 14.6%, 15.1%, and 6.3%, respectively, had anterior uveitis, intermediate uveitis, posterior or panuveitis, scleritis, ocular mucous membrane pemphigoid, and other forms of ocular inflammation.	19748676
Juvenile Temporal Arteritis, Inflammation	Altered Intercellular Communication	Juvenile temporal arteritis (JTA) is a nongranulomatous inflammation of the temporal artery with fragmentation of the internal elastic lamina and no concurrent systemic manifestations.	19748701
Inflammation, Intimal proliferation	Altered Intercellular Communication	We present a case of a 36-year-old Jamaican woman with a painful forehead nodule that showed histologic features of JTA, including intimal hyperplasia, lymphoeosinophilic inflammation of the vessel wall, and disruption of the internal elastic lamina; distinctive signet ringlike cytomorphologic alterations of the endothelial cells were noted as well.	19748701
Interstitial inflammation	Altered Intercellular Communication	Autopsy showed diffuse interstitial inflammation of both lungs consistent with drug-induced inflammation.	19749395
Inflammation, Coronary Arteriosclerosis, Coronary heart disease	Altered Intercellular Communication	Systemic and local inflammation plays a prominent role in the pathogenesis of atherosclerotic coronary artery disease, but the relationship of whole blood gene expression changes with coronary disease remains unclear.	19750006
Inflammation, Myocardial Ischemia	Altered Intercellular Communication	The effect of gaseous traffic-related air pollution on inflammation may be stronger in genetic subpopulations with ischemic heart disease.	19750100
Immunologic Deficiency Syndromes, HIV Infections	Altered Intercellular Communication	As those with HIV infection live longer, 'non-AIDS' condition associated with immunodeficiency and chronic inflammation are more common.	19751364
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	A population-based epidemiologic study of Helicobacter pylori infection and its association with systemic inflammation.	19751435
Inflammation	Altered Intercellular Communication	These may be mediated by an increase in systemic inflammation.	19751435
Communicable Diseases, Inflammation	Altered Intercellular Communication	Our data suggest that infection with H. pylori is associated with increased systemic inflammation.	19751435
Inflammation, "Alzheimers Disease", Impaired cognition, millicurie	Altered Intercellular Communication	Inflammation is proposed to play a role in the development of Alzheimer's disease, and may also be involved in the pathogenesis of mild cognitive impairment (MCI).	19751919
Inflammation, millicurie	Altered Intercellular Communication	These findings suggest the involvement of inflammation in the pathogenesis of MCI.	19751919
Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding, Ischemia	Altered Intercellular Communication	The risk of atrial fibrillation (AF) after coronary bypass surgery has been related to redox state, inflammation, and ischemia.	19752364
Oligospermia, Primary hypogonadism	Altered Intercellular Communication	Hormonal examination demonstrated hypergonadotropic hypogonadism, semen analysis showed severe oligoasthenoteratozoospermia.	19752597
Ischemia, Inflammation	Altered Intercellular Communication	Enterocyte shedding and epithelial lining repair following ischemia of the human small intestine attenuate inflammation.	19753114
Pleural Effusion, CTCAE, Granulomatous inflammation, Pneumonia, Interstitial, Pneumonia	Altered Intercellular Communication	Pleural effusion associated with pegylated interferon alpha and ribavirin treatment for chronic hepatitis C. Lung toxicity related to interferon (IFN) alpha typically takes a form of interstitial pneumonitis, granulomatous inflammation, or organizing pneumonia.	19753589
Cystic Adenomatoid Malformation of Lung, Congenital, Inflammation	Altered Intercellular Communication	Inflammation can be present in infantile congenital cystic adenomatoid malformation of the lung.	19753732
Cystic Adenomatoid Malformation of Lung, Congenital, Inflammation, Infancy	Altered Intercellular Communication	The absence of inflammation has generally been considered obligatory for the diagnosis of CCAM of the lung in the infantile period.	19753732
Inflammation, Structure of parenchyma of lung	Altered Intercellular Communication	Furthermore, it has been argued that chronic inflammation itself may influence the development of cystic lesions within lung parenchyma.	19753732
Suppurative inflammation, Deformity	Altered Intercellular Communication	We report a case of an 11-month-old infant with CCAM malformation of the lung type III associated with a super-impossed purulent inflammation and abscess formation.	19753732
Pain Distress Question	Altered Intercellular Communication	The second generation was heralded by research that demonstrated that newborns did demonstrate similar or even exaggerated physiological and hormonal responses to pain compared with those observed in older children and adults and that exposure to prolonged or severe pain may increase neonatal morbidity.	19754486
Inflammation, Neoplasms	Altered Intercellular Communication	Further diagnostic work-up included a fluorodeoxyglucose positron emission tomography (FDG-PET) of the whole body to search for occult inflammation or neoplasia.	19755199
Inflammation, therapeutic hemodilution	Altered Intercellular Communication	Clinical evaluation of minimized extracorporeal circulation in high-risk coronary revascularization: impact on air handling, inflammation, hemodilution and myocardial function.	19755462
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Chronic inflammation plays an important role in the development and progression of colorectal cancer.	19755647
Inflammation, pertussis vaccine	Altered Intercellular Communication	Booster doses of diphtheria-tetanus-acellular pertussis (DTaP) vaccines restore waning serum antibody values but frequently cause local inflammation.	19755930
Granuloma, Inflammation, Muscle hypertrophy, Ileitis, Ulcer, Lobular Endocervical Glandular Hyperplasia, Hypertrophy, Ileal ulcer	Altered Intercellular Communication	The following atypical features were identified (n; %): broad-based ulcer (99; 65%), appendiceal involvement (78; 51%), V-shaped ulcer (48; 31%), crypt-associated granuloma (42; 27%), isolated giant cells (39; 25%), discontinuous active inflammation (36; 24%), slit-like fissure (32; 21%), discontinuous chronic inflammation (16; 10%), ileal villous architectural distortion (12; 8%), neural hypertrophy (10; 7%), backwash ileitis (10; 7%), transmural inflammation (8; 5%), discontinuous ileitis (8; 5%), muscle hypertrophy (5; 3%), ileal ulcer (4; 3%), and ileal pyloric metaplasia (1; 1%).	19755970
Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	Six patients developed inflammation-related complications (Systemic Inflammatory Response Syndrome--SIRS) and they all showed a deeper postoperative decrease of FT3 value than non complicated subjects, even if the difference was not statistically significant (1st postop day 3.60 +/- 1.05 vs 2.47 +/- 0.61 p = 0.06).	19756315
Inflammation, Atherosclerosis	Altered Intercellular Communication	Preoperative FT3 value in patients with atherosclerosis is inversely correlated with markers of inflammation activity, mainly with fibrinogen.	19756315
Muscle of orbit, Myositis	Altered Intercellular Communication	On magnetic resonance (MR) imaging, muscle inflammation was measured with a region of interest set within the brightest extra-ocular muscle both on coronal turbo inversion recovery magnitude (TIRM) and on fat suppressed gadolinium-enhanced T1-weighted sequences.	19756565
Pain Distress Question, Inflammation	Altered Intercellular Communication	The subjects were 16 patients (20 shoulders) in whom pain was possibly derived from inflammation of the SAB.	19756670
Inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Abnormal activation of intracellular signaling molecules in lymphocytes by inflammatory cytokines can instigate the inflammation in SLE.	19756990
Hyperactive behavior, Inflammation Mediators, Lupus Erythematosus, Systemic	Altered Intercellular Communication	The inflammation-mediated activation of JNK and p38 MAPK signaling pathways in T and B lymphocytes can be the underlying intracellular mechanisms causing lymphocyte hyperactivity in SLE.	19756990
Crohn Disease, Inflammation	Altered Intercellular Communication	Infliximab in clinical routine: experience with Crohn's disease and biomarkers of inflammation over 5 years.	19757522
Inflammation, Lung Diseases, Obstructive, Intestinal Diseases, Ischemia	Altered Intercellular Communication	This finding may present in diverse conditions, such as obstructive pulmonary disease and intestinal disease, including obstruction, inflammation, or ischemia.	19758151
Coughing, ARCN1 gene, Hypersensitivity, Airway structure	Altered Intercellular Communication	Hypersensitivity of the cough reflex to inhaled capsaicin might reflect airway inflammation in stable COPD patients, which predisposes to frequent exacerbations.	19761536
Inflammation, Community acquired pneumonia	Altered Intercellular Communication	Biological markers as an expression of systemic inflammation have been recognised as useful for evaluating the host response in community-acquired pneumonia (CAP).	19762338
Inflammation, Liver damage	Altered Intercellular Communication	In addition, MRP14-deficient mice demonstrated decreased systemic inflammation, as reflected by lower cytokine plasma concentrations, and less severe liver damage.	19762566
Inflammation	Altered Intercellular Communication	Abdominal fat deposition is associated with increased inflammation, protein-energy wasting and worse outcome in patients undergoing haemodialysis.	19762603
HD Term Type, Inflammation	Altered Intercellular Communication	We tested the hypothesis that abdominal fat deposition in HD patients is a risk factor associated with both increased inflammation and protein-energy wasting (PEW), as well as elevated mortality risk.	19762603
Inflammation	Altered Intercellular Communication	Abdominal fat deposition in haemodialysis patients is linked to both inflammation and PEW, resulting in an increased mortality risk.	19762603
Necrosis	Altered Intercellular Communication	The anti-tumor necrosis factor (TNF)alpha medications demonstrate efficacy in the induction of remission and its maintenance in numerous chronic inflammatory conditions.	19764100
Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain and signs of inflammation in the eye recurred after 2 weeks.	19765479
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	Insulin resistance and inflammation may have an additional role in the link between cystatin C and cardiovascular disease in type 2 diabetes mellitus patients.	19765773
Inflammation	Altered Intercellular Communication	It may be worthwhile to focus on increasing the resilience of the airways to environmental insults in addition to improving strategies that modify adaptive immunity or suppress inflammation.	19766079
vascular inflammations, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Important biochemical markers for the low-grade vascular inflammation and endothelial dysfunction that characterize the earliest events in the pathogenesis of atherosclerosis are CRP and the adhesion molecules ICAM-1 and VCAM-1.	19766219
Inflammation, Arrhythmogenic Right Ventricular Dysplasia, Metabolic Syndrome X, Atherosclerosis	Altered Intercellular Communication	Increased left ventricular arrhythmogenicity in metabolic syndrome and relationship with myocardial performance, risk factors for atherosclerosis, and low-grade inflammation.	19766273
Inflammation, Myocardial dysfunction, Atherosclerosis, ETV3 wt Allele, Arrhythmogenic Right Ventricular Dysplasia	Altered Intercellular Communication	In conclusion, ventricular arrhythmogenicity is present in MetS and is associated with myocardial dysfunction, risk factors for atherosclerosis, and low-grade inflammation.	19766273
Heart Diseases, Inflammation	Altered Intercellular Communication	This association does not appear to be mediated by co-morbid conditions, cardiac disease severity, insulin resistance, inflammation, neurohormones, or adipokines.	19766751
Heart Diseases, Inflammation	Altered Intercellular Communication	This association does not appear to be mediated by co-morbid conditions, cardiac disease severity, insulin resistance, inflammation, neurohormones, or adipokines.	19766751
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	The associations of inflammation/immune responses with clinical presentations of Alzheimer's disease (AD) remain unclear.	19767111
Gingivitis, Inflammation, Periodontitis, Periodontal Diseases, Dental Plaque	Altered Intercellular Communication	Periodontal diseases, such as gingivitis and periodontitis, are characterized by bacterial plaque accumulation around the gingival crevice and the subsequent inflammation and destruction of host tissues.	19767584
Inflammation, Phase II/III Trial, Colorectal Carcinoma	Altered Intercellular Communication	The present study assesses the prognostic value of local and systemic inflammation in colon and rectal cancers and defines 3-year survival according to inflammation-based criteria for stage II/III disease.	19768511
Inflammation, Hyperplasia, Psoriasiform lesion, Follicular cyst	Altered Intercellular Communication	A skin biopsy was performed for each patient demonstrating cystic follicular dilatation with keratin plugging, dermal scarring, psoriasiform epidermal hyperplasia, and chronic inflammation of some of the follicles.	19769836
Macular Edema, Cystoid, Intraocular inflammation	Altered Intercellular Communication	Funduscopic examination revealed cystoid macular edema with no intraocular inflammation.	19769861
Endophthalmitis, CTCAE	Altered Intercellular Communication	The next day, endophthalmitis was diagnosed secondary to exuberant purulent inflammation.	19770723
Inflammation, Hypertension, CTCAE, Endothelial dysfunction	Altered Intercellular Communication	Biomarkers of inflammation and endothelial dysfunction and risk of hypertension among Inner Mongolians in China.	19770776
Inflammation, Hypertension, CTCAE, Endothelial dysfunction	Altered Intercellular Communication	These data suggest that inflammation and endothelial dysfunction may play a role in the cause of hypertension.	19770776
HD Term Type, "Huntingtons Disease Pathway	Altered Intercellular Communication	We investigated, retrospectively, the prevalence of gastroesophageal inflammation in patients with Huntington's disease (HD) during 10 years in our center.	19771391
Multinodular, Inflammation, Insect Bites, Dental Plaque	Altered Intercellular Communication	The patient had no remarkable medical history, no history of either acute inflammation or insect bite, and presented with a 5 cm solitary asymptomatic erythematous firm, multinodular and infiltrated plaque on the back for 12 months.	19771768
Inflammation, Ischemia	Altered Intercellular Communication	We hypothesize that stress-induced response by inflammation and/or ischemia may interfere in the physiological barrier that prevents any significant amount of PSA to gain the general circulation.	19773041
Inflammation	Altered Intercellular Communication	We tested whether organisational injustice contributes to chronic inflammation in a population of middle-aged men and women.	19773285
Inflammation, Carcinoma of lung, Pain Distress Question	Altered Intercellular Communication	Role of inflammation gene polymorphisms on pain severity in lung cancer patients.	19773451
Inflammation, Carcinoma of lung, Pain Distress Question	Altered Intercellular Communication	Therefore, we evaluated 59 single nucleotide polymorphisms in 37 inflammation genes in newly diagnosed non-Hispanic Caucasian lung cancer patients (n = 667) and assessed their association with pain severity.	19773451
Inflammation, Pain Distress Question	Altered Intercellular Communication	This study suggests the importance of inflammation gene polymorphisms in modulating pain severity.	19773451
Inflammation, Hodgkin Disease	Altered Intercellular Communication	Inflammation and tissue repair markers distinguish the nodular sclerosis and mixed cellularity subtypes of classical Hodgkin's lymphoma.	19773754
malignant disease, Hodgkin Disease	Altered Intercellular Communication	Classical Hodgkin's lymphoma (cHL), although a malignant disease, has many features in common with an inflammatory condition.	19773754
Inflammatory Bowel Diseases, Inflammatory disease of mucous membrane	Altered Intercellular Communication	There is increasing evidence that psychological stress can increase mucosal inflammation and worsen the course of inflammatory bowel disease (IBD).	19774642
Single organ dysfunction, Inflammation, Critical Illness	Altered Intercellular Communication	Inflammation, vitamin deficiencies and organ failure in critically ill patients.	19775037
Inflammation	Altered Intercellular Communication	It is unknown whether biochemical vitamin deficiencies in critical illness are associated with severity of illness, organ dysfunction, inflammation or mortality.	19775037
Loss, Inflammation, AICARDI-GOUTIERES SYNDROME	Altered Intercellular Communication	The gastrointestinal tract is an area of high cell loss, revealing early signs of systemic inflammation and we postulate that a systemic proinflammatory milieu occurs in Aicardi-Goutieres syndrome.	19775308
Gastrointestinal inflammation	Altered Intercellular Communication	Gastrointestinal inflammation should also be considered in these patients and treated appropriately.	19775308
Burning sensation, Inflammation, Xerostomia	Altered Intercellular Communication	The high prevalence of oral parafunctional habits and dry mouth symptoms in patients with BMS suggests that inflammation at the subclinical level due to repetitive microtrauma may cause burning mouth sensations.	19775760
Intermittent Claudication, Inflammation	Altered Intercellular Communication	Exercise in patients with intermittent claudication elicits signs of inflammation and angiogenesis.	19775917
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	There are contributions to understanding individual differences in normal cognitive ageing from genetics, general health and medical disorders such as atherosclerotic disease, biological processes such as inflammation, neurobiological changes, diet and lifestyle.	19776035
Inflammation, Muscular Atrophy, Blood Circulation	Altered Intercellular Communication	Patients with previous circulatory congestion had significantly more inflammation, more muscle wasting, and higher REE but lower activity energy expenditure and energy and protein intakes in keeping with an anorexia-cachexia syndrome.	19776138
Inflammation	Altered Intercellular Communication	The HFr group had a significantly higher grade of lobular inflammation than the other 4 groups.	19776184
Inflammation, Fatty Liver Disease	Altered Intercellular Communication	The distribution of lobular inflammation was predominant over portal inflammation, which is consistent with human NASH.	19776184
Inflammation	Altered Intercellular Communication	EGCG may be of value in the treatment of synovial inflammation.	19777241
Gastrointestinal dysmotility	Altered Intercellular Communication	These data suggest that SSc GI dysmotility may be caused by autoantibodies that inhibit the muscarinic neurotransmission.	19779020
Vascular Diseases, Inflammation, Telangiectasis, Raynaud Phenomenon, CREST Syndrome, Fibrosis Assessment, Scleroderma , Sclerodactyly, Calcinosis, Esophageal hypomotility	Altered Intercellular Communication	CREST syndrome is a variant of scleroderma characterized by calcinosis, Raynaud's phenomenon, esophageal hypomotility, sclerodactyly, and telangiectasia, and is a collagen vascular disease characterized by inflammation and fibrosis of multiple organs/tissues.	19779284
Inflammation, Necrosis	Altered Intercellular Communication	The histological examination revealed lobulated fibrofatty tissue showing congestion, acute inflammation and fat necrosis.	19779995
Inflammation, Heart failure	Altered Intercellular Communication	Red cell distribution width in heart failure: prediction of clinical events and relationship with markers of ineffective erythropoiesis, inflammation, renal function, and nutritional state.	19781428
Renal Insufficiency, Inflammation	Altered Intercellular Communication	The described correlations between RDW and inflammation, ineffective erythropoiesis, undernutrition, and impaired renal function may facilitate the understanding why this marker is associated with adverse outcomes in HF.	19781428
Inflammation, Terminal Osseous Dysplasia and Pigmentary Defects	Altered Intercellular Communication	Inflammation and sympathetic overdrive may also associate with TOD.	19781703
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Association of LDL cholesterol and inflammation with cardiovascular events and mortality in hemodialysis patients with type 2 diabetes mellitus.	19781835
Pneumonitis	Altered Intercellular Communication	Imaging at 6 months demonstrated no anastomotic concerns and resolution of residual pulmonary inflammation.	19782515
Inflammation	Altered Intercellular Communication	Log leptin, adiponectin and L/A ratio were significantly associated with variables of systemic inflammation, after proper adjustments, both on admission and in stable condition.	19782551
Inflammation, Immunoglobulin G4 deficiency	Altered Intercellular Communication	There was a significant association between severity of gingival inflammation and reduced number of B- and/or CD3+/CD4+ T cells combined with IgA+IgG4 deficiency.	19782616
Inflammation, Atherosclerosis	Altered Intercellular Communication	Accumulating evidence suggests that inflammation plays an essential role in the pathogenesis of atherosclerosis.	19784814
Inflammation, Anterior uveitis	Altered Intercellular Communication	In patients with CMV anterior uveitis, intravitreal ganciclovir injection as a loading dose with or without the following oral valganciclovir can control the inflammation and IOP well.	19784845
Autoimmune Diseases, Lupus Erythematosus	Altered Intercellular Communication	Background Lupus erythematosus (LE) is a chronic, autoimmune disease resulting from an interaction of genetic, environmental and hormonal factors and characterized by a spectrum of clinical forms with variable evolution from a localized cutaneous form to a life-threatening systemic form.	19785596
Inflammation, Dermatitis, Atopic, Skin Diseases, Eczematous, Data types - Address, Dryness (characteristic), Pruritus	Altered Intercellular Communication	Atopic dermatitis (AD) is a chronic relapsing eczematous skin disease characterized by pruritus and inflammation and accompanied by cutaneous physiological dysfunction (dry and barrier-disrupted skin).	19785716
Granulomatous inflammation	Altered Intercellular Communication	Brain biopsy revealed granulomatous inflammation and remnants of worm eggs.	19785826
Inflammation, Chronic sinusitis	Altered Intercellular Communication	Biofilms correlate with TH1 inflammation in the sinonasal tissue of patients with chronic rhinosinusitis.	19786211
Inflammation, Sarcoidosis	Altered Intercellular Communication	By using antigenic peptides presented in vivo in the lungs of sarcoidosis patients, we have identified blood and lung T cell autoimmune responses that may help sustain the inflammation in this disease.	19786367
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Effect of pioglitazone on systemic inflammation is independent of metabolic control and cardiac autonomic function in patients with type 2 diabetes.	19787290
Blepharitis, Asthma, Conjunctivitis, Diabetes Mellitus	Altered Intercellular Communication	The patients were divided into four groups: a control group (without local or systemic risk factors), those with local risk factors (chronic use of topical medications, contact lens wear, blepharitis, chronic eyelid or conjunctival inflammation), those with systemic risk factors (immunosuppression, diabetes, autoimmune conditions, and asthma), and those with both.	19787587
palladium	Altered Intercellular Communication	While some of these cells likely undergo degeneration, the strong up-regulation of Herp in glia could help to explain the inflammation-like changes observed in PD ("neuroinflammation") as it has been shown that the unfolded protein response serves as an important regulator of inflammatory genes in other organs.	19788048
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) characterized by local and systemic effects of inflammation has a wide range of biochemical markers implicated directly or indirectly to its pathogenesis.	19788068
Optic perineuritis	Altered Intercellular Communication	Optic perineuritis (OPN) is an inflammatory condition involving the optic nerve sheath because of a variety of causes.	19788669
Malaria, Falciparum, Peripheral gangrene, Plasmodium falciparum, SLC25A10 gene	Altered Intercellular Communication	[DIC and peripheral gangrene in a severe Plasmodium falciparum malaria: the coagulation-inflammation cycle with Plasmodium falciparum as a model].	19789130
Inflammation, Malaria, SLC25A10 gene	Altered Intercellular Communication	Pathophysiological mechanisms leading to DIC in malaria can be used as a model to explain the relation between coagulation and inflammation.	19789130
Inflammation	Altered Intercellular Communication	Therapeutic targeting of coagulation, by acting on inflammation, could be useful to limit the coagulation-inflammation cycle.	19789130
Inflammation, Asthma	Altered Intercellular Communication	To analyze and compare computed tomographic (CT) bronchial measurements in patients with asthma and healthy subjects and to correlate bronchial morphometric parameters with functional data and immunohistologic markers of airway remodeling and inflammation.	19789219
Colorectal Carcinoma	Altered Intercellular Communication	As one of the largest data sets analyzed to establish that younger women with MCRC survive longer than younger men, hormonal status not only seems to play an important role in the development and pathogenesis of colorectal cancer but also may be of prognostic significance.	19789331
ARCN1 gene, Respiratory Insufficiency, Inflammation, exacerbation acute	Altered Intercellular Communication	Nutritional status in relation to respiratory impairment and systemic inflammation in patients with acute exacerbations of COPD.	19789512
ARCN1 gene, Respiratory Insufficiency, Inflammation	Altered Intercellular Communication	Knowledge of the effects of undernourishment on the severity of respiratory impairment, systemic inflammation and oxidative stress during acute exacerbations of COPD (AECOPD) is limited.	19789512
Inflammation	Altered Intercellular Communication	In patients with AECOPD, we assessed the relationships between BMI, lung function, and markers of systemic inflammation and oxidative stress.	19789512
Inflammation	Altered Intercellular Communication	During the long-term follow up of 62 patients with the Frey procedure, eight patients had relapse of inflammation and required reoperation.	19789835
Inflammation, Waldenstrom Macroglobulinemia	Altered Intercellular Communication	At the time of aortic surgery, a transmural lymphoplasmacytic infiltrate was detected in the patient's aorta, with a principal focus of inflammation within the media.	19790067
Inflammation, Disease	Altered Intercellular Communication	Patients with proinflammatory HDL had higher measures of systemic inflammation, and a significant correlation was observed between RA disease activity (using the Disease Activity Score in 28 joints) and the HDL inflammatory index (r = 0.54, P < 0.0001).	19790070
Refractory anemias, Inflammation, Cardiovascular morbidity	Altered Intercellular Communication	The antiinflammatory function of HDL was inversely correlated with systemic inflammation in RA patients and may warrant further investigation as a mechanism by which active RA increases cardiovascular morbidity and mortality.	19790070
Inflammation	Altered Intercellular Communication	A preponderance of 16alpha-hydroxylated estrogens is an unfavorable sign in synovial inflammation.	19790073
Inflammatory, Inflammation	Altered Intercellular Communication	In inflammatory lesions, sympathetic nerve fibers disappear soon after the start of inflammation.	19790074
Inflammation, Autoimmune Chronic Hepatitis	Altered Intercellular Communication	In the multivariate Cox analysis, only the presence of moderate to severe inflammation (HR, 6.9; 95% CI, 1.76-26.96; P = 0.006) and high IgG levels before liver transplantation (HR, 7.5; 95% CI, 1.45-38.45; P = 0.02) were independently associated with the risk of autoimmune hepatitis recurrence.	19790153
Intraocular inflammation, NCI CTEP SDC Retinoblastoma Sub-Category Terminology	Altered Intercellular Communication	Invasive surgical procedures should be avoided in children presenting with atypical, chronic, unilateral intraocular inflammation of unknown cause until retinoblastoma is excluded.	19791731
ARCN1 gene, Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	It is also hypothesized that systemic inflammation in COPD increases the risk for cardiac events such as myocardial infarction.	19791824
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Diabetes is a proinflammatory state with increased levels of circulating cytokines suggesting a causal role for inflammation in its etiology.	19792847
Inflammation, Asthma	Altered Intercellular Communication	Eosinophilic inflammation has a central role in the pathogenesis of asthma.	19793065
Inflammation, Angioendotheliomatosis, Necrosis	Altered Intercellular Communication	Muscle biopsy showed myopathic changes, intravascular large B-cell lymphoma but no inflammation or fibre necrosis; the patient's serum cross-reacted with an unidentified nuclear antigen of approximately 45 kDa present in muscle and lymphoma cells.	19793654
Inflammation, Endotoxemia	Altered Intercellular Communication	Experimental endotoxemia induces adipose inflammation and insulin resistance in humans.	19794059
Inflammation, Metabolic Syndrome X, Diabetes Mellitus, Non-Insulin-Dependent, physiopathological	Altered Intercellular Communication	An emerging model of metabolic syndrome and type 2 diabetes is of adipose dysfunction with leukocyte recruitment into adipose leading to chronic inflammation and insulin resistance (IR).	19794059
Inflammation	Altered Intercellular Communication	We demonstrate, for the first time in humans, that acute inflammation induces systemic IR following modulation of specific adipose inflammatory and insulin signaling pathways.	19794059
Inflammation, Traumatic injury	Altered Intercellular Communication	When disturbed following PEC injury, the increase in permeability of this layer to filtered protein is a mechanism underlying periglomerular inflammation characteristic of anti-GBM disease.	19794110
RANGAP1 wt Allele, Inflammation	Altered Intercellular Communication	In the SD patients, small clusters of inflammation were found in the reticular formation surrounding solitary tract, spinal trigeminal, and ambigual nuclei, inferior olive, and pyramids.	19795469
Inflammation, Leukocytosis, Chlamydia, Vaginal Diseases, Actinomyces, Candida (fungus)	Altered Intercellular Communication	The Dutch cytological coding system, KOPAC, enables to code for eight inflammatory events, that is koilocytosis (related to human papillomavirus (HPV)), Trichomonas, dysbacteriosis [related to bacterial vaginosis (BV)], Candida, Gardnerella, Actinomyces, Chlamydia, and non-specific inflammation (leucocytosis).	19795485
Inflammation, Necrosis	Altered Intercellular Communication	Biopsy findings showed an ill defined granulomatous process with chronic inflammation and necrosis.	19796470
Orbital Pseudotumor	Altered Intercellular Communication	These data suggest a possible role for PDGF-BB in regulating orbital inflammation in GO and identify the PDGF signaling cascade as a therapeutic target in GO.	19797221
Refractory anemias, Inflammation, Rheumatoid Factor, Pneumonitis	Altered Intercellular Communication	Aseptic pulmonary nodular inflammation corresponding to rheumatoid nodules or noncaseating granulomatous inflammation can occur during anti-TNF-alpha therapy for RA, mainly etanercept.	19797509
Pneumonitis	Altered Intercellular Communication	These cases of pulmonary nodular inflammation generally have a benign course and do not systematically require withdrawal of treatment.	19797509
Inflammation, Coronary heart disease, Atherosclerosis	Altered Intercellular Communication	Hemostasis, inflammation, and fatal and nonfatal coronary heart disease: long-term follow-up of the atherosclerosis risk in communities (ARIC) cohort.	19797708
Inflammation, Cardiac Death, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	This study examines the hypothesis that chronic inflammation is associated with a higher risk of cardiac death compared to the risk of nonfatal myocardial infarction.	19797708
Asthma, Bronchitis	Altered Intercellular Communication	To compare bronchial inflammation and remodeling in never-smokers, ex-smokers, and current smokers with asthma.	19797761
Cessation of life, Inflammation	Altered Intercellular Communication	The inclusion of the C-reactive protein (CRP) inflammation marker into the model highly improved the power of death prediction.	19797975
Communicable Diseases	Altered Intercellular Communication	We speculate that the pathogenesis involves increased platelet production due to megakaryopoietic stimulators induced by an infectious or inflammatory condition.	19798040
Inflammation, Obesity	Altered Intercellular Communication	Relationships among obesity, inflammation, and insulin resistance in African Americans and West Africans.	19798069
Inflammation, Obesity	Altered Intercellular Communication	Several research studies in different populations indicate that inflammation may be the link between obesity and insulin resistance (IR).	19798069
Inflammation	Altered Intercellular Communication	In both populations, BMI was associated with markers of inflammation and with HOMA(IR), and these associations remained significant after adjusting for sex and age.	19798069
Inflammation	Altered Intercellular Communication	Interestingly, none of the associations between markers of inflammation and IR remained significant after adjusting for BMI.	19798069
Left Ventricular Hypertrophy, Inflammation, Cancer-related fatigue, Arteriovenous fistula, Anemia, Hypertension, CTCAE, Chronic Kidney Diseases	Altered Intercellular Communication	After RT LVH risk factors were age, duration of chronic renal failure (CRF) and pretransplantation dialysis, reduced mass of the operating nephrons, arterial hypertension, anemia, functioning of arterio-venous fistula (AVF) and chronic inflammation syndrome.	19799199
Inflammation	Altered Intercellular Communication	Adipose tissue contributes in energy, lipid homeostasis and inflammation, through the adipokines it releases.	19800327
Asthma, MS4A2 wt Allele, Helminthiasis	Altered Intercellular Communication	Parasitic helminth infections can protect against allergic airway inflammation in experimental models and have been associated with a reduced risk of atopy and a reduced course of asthma in some observational studies.	19800680
Pneumonitis, Ulcerative Colitis	Altered Intercellular Communication	Moreover, severe lung inflammation was only observed in mice intranasally infected with the isolate from the UC form with the increase of bacterial load.	19800962
Inflammation, Fibrosis Assessment, Depressed mood, Depression, CTCAE	Altered Intercellular Communication	Inflammation markers were also elevated in depressed participants (CRP, p=0.014; WBC, p=0.075; fibrinogen, p=0.074), but these inflammation markers did not account for the relationship between depression and fibrosis markers.	19800964
Pancreatitis, AURKAIP1 gene, Pancreatic calcification, Abdominal Pain, Atrophic	Altered Intercellular Communication	In a separate cohort of patients with AIP from our database, we identified patients who presented with features of AP (>/=2 of abdominal pain, increased pancreatic enzymes, pancreatic inflammation determined by imaging analyses) or CP (>/=1 of pancreatic calcification, irregular main pancreatic duct dilation, or marked atrophy) and determined their clinical profile.	19800984
vascular inflammations, Hypertension, CTCAE, Cardiovascular Diseases	Altered Intercellular Communication	We have earlier shown that olmesartan reduces mediators of vascular inflammation in patients with hypertension and cardiovascular disease.	19801149
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	Elevated osteopontin levels in hypertensive patients correlate with adhesion molecules and inflammation markers.	19801149
Inflammation, Hematoma, Edema	Altered Intercellular Communication	The relationships of residue hematoma volume to brain edema, inflammation factors and the long-term prognosis of HBGH patients were studied.	19801153
Inflammation, Back Pain	Altered Intercellular Communication	The area of inflammation appeared two days after physiotherapy sessions prescribed for lower back pain.	19801259
Inflammation, Kidney Failure	Altered Intercellular Communication	Laboratory examinations revealed inflammation associated with moderate renal failure.	19801259
Cranial nerve palsies, Disorder of the optic nerve, Inflammation, Uveitis	Altered Intercellular Communication	Although most common ophthalmologic findings include optic neuropathy and uveitis, cranial nerve palsies may also present secondary to intracranial inflammation.	19801340
Inflammation, Asthma	Altered Intercellular Communication	IL-33, a new member of the IL-1 cytokine family, promotes Th2 inflammation, but evidence on the implications of this cytokine in asthma is lacking.	19801525
Airway structure	Altered Intercellular Communication	Induced sputum cytology and protein biomarkers can be used to assess airways inflammation.	19801580
Airway structure	Altered Intercellular Communication	We hypothesized that other sputum metals may be affected by airways inflammation and investigated their potential value as biomarkers.	19801580
Airway structure, Bronchiectasis	Altered Intercellular Communication	These results suggest a relationship of high concentrations of total zinc and iron with airways inflammation in CF and non-CF bronchiectasis, with longitudinal changes being observed in CF.	19801580
Airway structure, Obesity	Altered Intercellular Communication	To investigate the association between obesity and airway inflammation and spirometric parameters in local children.	19801691
Airway structure	Altered Intercellular Communication	Increased airway inflammation as revealed by exhaled nitric oxide concentration was found in obese non-asthmatic children.	19801691
Disease, Parinaud Syndrome, Inflammatory abnormality of the eye, Juxtapapillary focal retinitis AND retinochoroiditis	Altered Intercellular Communication	It can present with a wide spectrum of ocular diseases including neuroretinitis, Parinaud's oculoglandular syndrome, and other forms of intra-ocular inflammation.	19801700
Compartment syndromes, Inflammation	Altered Intercellular Communication	This inflammation can, in rare cases, lead to the development of a compartment syndrome.	19801954
Inflammation	Altered Intercellular Communication	Ninety two percent of cases had chronic inflammation in the gallbladder wall.	19802413
Inflammation, Cachexia	Altered Intercellular Communication	Chronic inflammation is one of the main features of cancer cachexia.	19802504
Limbic Encephalitis, Temporal Lobe	Altered Intercellular Communication	MRI brain revealed bilateral temporal lobe inflammation consistent with limbic encephalitis.	19804892
Inflammation, Calcinosis	Altered Intercellular Communication	The location of the plaques, type of plaques, presence of inflammation and calcification were assessed.	19805952
Steatohepatitis, Inflammation	Altered Intercellular Communication	Inconsistent assessment of histological features of steatohepatitis (lobular inflammation, portal inflammation, hepatocyte ballooning, and Mallory hyaline) was documented.	19806055
Thrombosis of cerebral veins, Vertical Talus, Traumatic injury	Altered Intercellular Communication	Cerebral venous thrombosis was relatively more common in women and hormonal factors may predispose to CVT compared to DVT/PE, while trauma, immobilisation and surgery may be less important in the pathophysiology of CVT.	19806246
vinyltriethoxysilane, Unknown (origin) (qualifier value), Inflammation, Thromboembolism	Altered Intercellular Communication	The aim of our study was to evaluate whether elevated clotting factors, which have been linked to chronic sub-clinical inflammation and arterial thromboembolic disease, have a higher prevalence in idiopathic VTE compared to secondary VTE.	19806251
vinyltriethoxysilane, Unknown (origin) (qualifier value), Inflammation, Arterial thromboembolism	Altered Intercellular Communication	Our data show that markers of inflammation, such as hs-CRP, fibrinogen, and factor VIII, are at higher levels in patients with idiopathic compared to secondary VTE, supporting the hypothesis that idiopathic VTE and arterial thromboembolism share common risk factors.	19806251
Inflammation, Dental Plaque	Altered Intercellular Communication	Such platelet-mediated inflammation could be involved in atherogenesis and plaque destabilisation.	19806256
Adenocarcinoma, Inflammation, Neoplasms, Necrosis	Altered Intercellular Communication	Major diagnostic pitfalls included obscuring acute inflammation, necrosis, tumor cells that mimicked benign cells with radiation/reactive atypia, and the under recognition of mucin-containing adenocarcinoma cells.	19806643
Inflammation, Erythema, Swelling, Pain Distress Question	Altered Intercellular Communication	In HA-treated patients, erythema and inflammation, swelling, and pain were most frequent.	19807757
Inflammation, Vasculitis, CTCAE, Congenital Abnormality	Altered Intercellular Communication	Furthermore, surgical manipulation in WG patients is associated with increased bony abnormalities and greater elevations of L-M scores, possibly because of worsening vasculitis and/or inflammation.	19807982
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Mineral metabolism and inflammation in chronic kidney disease patients: a cross-sectional study.	19808245
Inflammation, Abnormal metabolism, Chronic Kidney Diseases	Altered Intercellular Communication	Mineral metabolism abnormalities and inflammation are concerns in chronic kidney disease (CKD).	19808245
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Elevated serum P might play a role in the development of inflammation in CKD.	19808245
Inflammation, Heart failure, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome, inflammation, and incident heart failure in the elderly: the cardiovascular health study.	19808298
Metabolic Syndrome X, ETV3 wt Allele, Congestive heart failure	Altered Intercellular Communication	Inflammation markers and metabolic syndrome (MetS) are associated with risk of congestive heart failure (CHF).	19808298
Inflammation, ETV3 wt Allele, Congestive heart failure	Altered Intercellular Communication	We evaluated whether combining inflammation markers and MetS provided additive information for incident CHF and if incorporating inflammation markers to the MetS definition added prognostic information.	19808298
Inflammation, ETV3 wt Allele, Congestive heart failure	Altered Intercellular Communication	MetS and elevated inflammation markers were independently associated with CHF risk (hazard ratios, 95% CI: 1.32, 1.16 to 1.51 for MetS; 1.53, 1.34 to 1.75 for CRP; 1.37, 1.19 to 1.55 for IL-6).	19808298
Inflammation, ETV3 wt Allele, Congestive heart failure	Altered Intercellular Communication	MetS and inflammation markers provided additive information on CHF risk in this elderly cohort.	19808298
ETV3 wt Allele	Altered Intercellular Communication	Inflammation-incorporated MetS definitions identified more participants with the same risk level as ATPIII MetS.	19808298
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Considering inflammation markers and MetS together may be useful in clinical and research settings.	19808298
Inflammation, Congestive heart failure	Altered Intercellular Communication	Inflammation may be a causative factor in congestive heart failure (CHF).	19808373
Brief Resilience Scale, Inflammation, Fibrosis Assessment, Hypertrophy	Altered Intercellular Communication	We retrospectively analyzed BrS biopsy samples from 21 unrelated patients for histopathologic abnormalities (hypertrophy, fibrosis, inflammation, fatty tissue) together with the patients' clinical, genetic, and imaging data.	19808440
Inflammation, Calcinosis	Altered Intercellular Communication	Relationships among regional arterial inflammation, calcification, risk factors, and biomarkers: a prospective fluorodeoxyglucose positron-emission tomography/computed tomography imaging study.	19808576
Arterial calcification, Plaque, Atherosclerotic	Altered Intercellular Communication	We explored how atherosclerotic plaque inflammation varies across arterial territories and how it relates to arterial calcification.	19808576
Inflammation, Vascular Diseases	Altered Intercellular Communication	We also tested the hypotheses that the degree of local arterial inflammation measured by PET is correlated with the extent of systemic inflammation and presence of risk factors for vascular disease.	19808576
Inflammation, Calcinosis	Altered Intercellular Communication	Calcification and inflammation rarely overlapped within arteries (carotid artery FDG uptake versus calcium score, r=-0.42, P=0.03).	19808576
Calcinosis, Plaque, Atherosclerotic	Altered Intercellular Communication	This study shows that FDG PET imaging can increase our knowledge of how atherosclerotic plaque inflammation relates to calcification, serum biomarkers, and vascular risk factors.	19808576
Inflammation, Calcinosis, Atherosclerosis	Altered Intercellular Communication	Plaque inflammation and calcification rarely overlap, supporting the theory that calcification represents a late, burnt-out stage of atherosclerosis.	19808576
Inflammation	Altered Intercellular Communication	Inflammation in one arterial territory is associated with inflammation elsewhere, and the degree of local arterial inflammation is reflected in the blood levels of several circulating biomarkers.	19808576
Inflammation	Altered Intercellular Communication	PDUS may be useful to detect at diagnosis the patients with most active inflammation who have a higher risk of relapses/recurrences.	19808693
Inflammation, Fatigue	Altered Intercellular Communication	Surgery-induced inflammation in relation to age, muscle endurance, and self-perceived fatigue.	19808837
Inflammation, Fatigue	Altered Intercellular Communication	Surgery-induced inflammation is related to reduced muscle endurance and the sensation of fatigue.	19808837
Flaked Material, Inflammation, Parakeratosis, Necrotic debris	Altered Intercellular Communication	Biopsies from confirmed EDS patients showed sloughing and flaking of superficial squamous epithelium with occasional bullous separation of the layers, parakeratosis, and varying degrees of acute or chronic inflammation.	19809273
Acute inflammation	Altered Intercellular Communication	Fungal elements were identified in 3 patients, but were not associated with acute inflammation.	19809273
Inflammation	Altered Intercellular Communication	Interestingly, the marker of chronic inflammation, IL-6, was positively associated with methylation of MGMT (P = 0.004), RARbeta (P = 0.002), and RASSF1A (P = 0.0081) as well as the total number of methylated genes (P < 0.0001), indicating the important role of IL-6 in maintaining promoter methylation of these genes.	19809523
Juvenile-Onset Still Disease	Altered Intercellular Communication	Adult-onset Still's disease (AOSD) is an uncommon inflammatory condition of unknown origin and pathogenesis.	19809819
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Our results confirm that ADMA and SDMA levels are increased in ESRD patients and suggest that a link may exist with inflammation and nutritional status.	19809995
Granuloma, Pleural Tuberculosis, Pleurisy, Comorbidity	Altered Intercellular Communication	Comparison of clinical, X-ray, laboratory, morphological, and immunological data in patients of the first (1978-1987) and second (1998-2007) periods has revealed the signs characteristic of the negative pathomorphism of the disease: progressive latency of tuberculous pleurisy and a lower Mantoux reaction, a lower detection rate for epithelioid giant-cell granulomas in the patients' biopsy specimens, a higher rate of pleural tuberculous inflammation, an increased frequency of comorbidity, a higher drug resistance rate in Mycobacterium tuberculosis, and decreased therapeutic efficiency.	19810178
Inflammation, Esophagitis	Altered Intercellular Communication	Endoscopy showed erosive cesophagitis on day 5 (D5) and ulcerated bleeding inflammation of the entire colon and rectum on D26.	19810615
Vasculitis, thromboembolic, Vasculitis of large artery	Altered Intercellular Communication	Activated circulating leukocytes and platelets could contribute to indolent vessel inflammation and possibly to thromboembolic events in patients with systemic large vessel vasculitis.	19811309
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Hypertension, systemic inflammation and body weight in relation to lung function impairment-an epidemiological study.	19811383
Inflammation	Altered Intercellular Communication	Recent reports on the simultaneous occurrence of systemic inflammation and airflow obstruction are usually based on a highly selective patient population, but their importance warrants further evaluation in the general population.	19811383
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Hypertension, BMI and systemic inflammation affect lung function independently of each other.	19811383
vascular inflammations	Altered Intercellular Communication	Higher levels of sRAGE in symptomatic patients may be markers of a higher degree of vascular inflammation in such patients.	19811526
vascular inflammations, Thrombosis, Atherosclerosis	Altered Intercellular Communication	Expression of inducible nitric oxide synthase (iNOS) is a marker of vascular inflammation which can result in thrombosis and atherosclerosis.	19811579
Inflammation, Neoplasms	Altered Intercellular Communication	The patient recovered well, and the primary tumor was resected after remission of the local inflammation.	19811627
Neurogenic Inflammation	Altered Intercellular Communication	The abundance of SP fibres around the human cerebral microvasculature, particularly post capillary venules, together with the changes observed following TBI in perivascular axons, cortical neurones and astrocytes suggest a potentially important role for substance P in neurogenic inflammation following human TBI.	19812951
Inflammation, Atherosclerosis	Altered Intercellular Communication	Although peroxisome proliferator-activated receptor (PPAR)gamma activation reduces inflammation and atherosclerosis, expression of PPARgamma in cells and its modulation by smoking are poorly investigated.	19814730
Pneumonitis	Altered Intercellular Communication	Long-term cigarette smoking is associated with pulmonary inflammation, but the acute effects of smoking have been less well studied.	19816000
Inflammation	Altered Intercellular Communication	Analysis of the exhaled breath condensate (EBC) can provide noninvasive markers that might be indicative of inflammation.	19816000
Inflammation	Altered Intercellular Communication	The reduced pH in chronic smokers shows cigarette-induced inflammation.	19816000
Airway structure, Asthma	Altered Intercellular Communication	The stability of airway inflammation in asthma over time is not known, yet this information is crucial to inflammation-based patient management.	19816004
Airway structure, Asthma	Altered Intercellular Communication	A cut point of 3% eosinophils should be used to distinguish eosinophilic from non-eosinophilic airway inflammation in asthma.	19816004
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	Inflammation might link posttraumatic stress disorder (PTSD) with an increased risk of cardiovascular events.	19816056
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	The findings provide further evidence for altered inflammation in PTSD.	19816056
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	Comorbid depressive symptoms ought to be considered to disentangle the unique associations of PTSD caused by MI and systemic inflammation.	19816056
Inflammation, Eosinophilic cystitis	Altered Intercellular Communication	Eosinophilic inflammation in the middle ear induces deterioration of bone-conduction hearing level in patients with eosinophilic otitis media.	19816234
Inflammation, Bacterial Infections	Altered Intercellular Communication	These findings suggest that not only bacterial infection but also eosinophilic inflammation in the middle ear may damage the inner ear.	19816234
Inflammation, Bone-conduction hearing aid	Altered Intercellular Communication	The present study was performed to determine whether eosinophilic inflammation is indeed related to deterioration of bone-conduction hearing level (BCHL).	19816234
Inflammation	Altered Intercellular Communication	Inflammation is associated with increased body mass and purportedly with increased size of adipose cells.	19816674
Inflammation	Altered Intercellular Communication	We sought to determine whether increased size of adipose cells is associated with localised inflammation in weight-stable, moderately obese humans.	19816674
Inflammation	Altered Intercellular Communication	The observed association between small adipose cells and inflammation may reflect impaired adipogenesis and/or terminal differentiation.	19816674
Inflammation	Altered Intercellular Communication	This question and whether small vs large adipose cells contribute differently to inflammation in adipose tissue are topics for future research.	19816674
Ischemia, Compression, Inflammation	Altered Intercellular Communication	This may result from compression, ischemia, inflammation, or metabolic and toxic etiologies.	19817243
Inflammation	Altered Intercellular Communication	Costochondritis, an inflammation of costochondral junctions of ribs or chondrosternal joints of the anterior chest wall, is a common condition seen in patients presenting to the physician's office and emergency department.	19817327
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Its pathophysiology is marked by a gradual degenerative process accompanied by low-grade inflammation, and, although there is a strong correlation between age and OA risk, the abnormal changes that occur in the articular cartilage of people with OA differ notably from the typical changes associated with joint aging in several important ways.	19817508
APP gene, Inflammation, Apolipoprotein E, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Apolipoprotein E (ApoE) genotype has been associated with systemic inflammation and athero-thrombosis however the association with abdominal aortic aneurysm (AAA) has not been previously examined.	19818961
Vascular Diseases, Malnutrition, Inflammation	Altered Intercellular Communication	Furthermore, serum albumin is paradoxically linked to vascular disease under conditions both of overnutrition and of malnutrition and inflammation complex.	19819455
Inflammation, Helicobacter-associated gastritis	Altered Intercellular Communication	The number of Tregs was elevated in H. pylori-associated gastritis, where it was positively correlated with the grade of chronic inflammation and the number of lymphoid follicles.	19819643
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Acute decline in renal function, inflammation, and cardiovascular risk after an acute coronary syndrome.	19820133
Heart Diseases, Inflammation	Altered Intercellular Communication	The prognostic significance of worsening renal function has also been shown in various cohorts of cardiac disease; however, the predictors of worsening renal function and the contribution of inflammation remains to be established.	19820133
Inflammation, Kidney Diseases	Altered Intercellular Communication	CRP is an independent predictor for subsequent decline in renal function and reinforces the idea that inflammation may be related to the pathophysiology of progressive renal disease.	19820133
Pancreatitis	Altered Intercellular Communication	There was a significant correlation between CT and MR gradings for pancreatic or peripancreatic inflammation (r = 0.688, P < 0.01).	19820487
Exanthema, Weakness, Heliotropium europaeum, Myositis, Dermatomyositis	Altered Intercellular Communication	Dermatomyositis is an unknown cause's disease that in general is characterized by muscular inflammation with weakness and typical skin rash (heliotrope and Gottron's papules).	19820679
Acute respiratory failure, Oliguria	Altered Intercellular Communication	Highest basal comorbility of patients, oliguria and malnutrition-inflammation dates are princess prognosis and mortality factors in ARF today A new approach is needed in ARF because this new type/class of population.	19820755
Inflammation	Altered Intercellular Communication	Oxidative stress and a subclinical inflammation are crucial factors in its development.	19820759
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	Involvement of the cornea endothelium during uveitis has not been extensively studied even though it might participate in or constitute a target of ocular inflammation.	19820783
Structure of gastroduodenal artery, Plaque, Amyloid, Amyloidosis	Altered Intercellular Communication	This is the first case report of RA-related systemic reactive AA amyloidosis histopathologically demonstrating rapid regression of amyloid deposits on gastroduodenal mucosa after adequate suppression of the underlying inflammatory condition.	19820941
Inflammation	Altered Intercellular Communication	Involvement of chronic inflammation in methylation induction was suggested.	19821005
Refractory anemias, Inflammation, deformities qualifier, Fracture	Altered Intercellular Communication	The generalized effect of inflammation on bone may result in a decreased quality of bone and is associated with an increased risk of fractures and deformities, both in RA and AS.	19822048
Shock, Failure, Spinal Fractures	Altered Intercellular Communication	Bone fragility is also due to changes in structural properties resulting from inflammation-induced bone failure in the spine in combination with reduced capacity of shock absorption leading to vertebral fractures.	19822048
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	This study was carried out to analyze the expression of Netrins and their receptors in synovial cells of patients with RA, OA, and control subjects without synovial inflammation.	19822088
Disease, Inflammation, Traumatic injury, Malignant Neoplasms	Altered Intercellular Communication	The most common etiological factors of this syndrome include diseases or trauma of the central nervous system and malignant tumor or inflammation of the lung.	19822501
Inflammation, Biliary calculi, Virus Diseases, Alcohol abuse, Traumatic injury	Altered Intercellular Communication	The pancreas reacts by enzymatic autodigestion and inflammation to external and internal factors: alcohol abuse, trauma, biliary stones, and viral infections.	19822503
Pancreatitis	Altered Intercellular Communication	The diffuse spread of pancreatic inflammation may form a retroperitoneal phlegmon.	19822503
Inflammation, Adenoma	Altered Intercellular Communication	Changes in inflammation markers were not associated with adenoma recurrence.	19822838
Inflammation, Adenoma of large intestine	Altered Intercellular Communication	Nevertheless, inflammation markers do not mediate the chemopreventive effect of aspirin on colorectal adenomas.	19822838
Inflammation, Neoplasms	Altered Intercellular Communication	Univariate analysis revealed that significant prognostic factors for poorer survival were male gender (P = 0.026), age older than 65 years (P = 0.013), the presence of inflammation (P = 0.009), moderately or poorly differentiated tumor (P < 0.001), nonpolypoid gross type (P = 0.003), and pT stage (P < 0.001).	19823903
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	The common variant in the GSTM1 and GSTT1 genes is related to markers of oxidative stress and inflammation in patients with coronary artery disease: a case-only study.	19823950
Inflammation	Altered Intercellular Communication	There was an increased exposure of the markers MMP-9 and MMP-2, which was most evident in the fundal GM and correlated with the activity of inflammation.	19824429
Refractory anemias, Inflammation, NLRP3 gene, Degenerative polyarthritis	Altered Intercellular Communication	The NALP3 inflammasome activity does not account for the difference in level of inflammation between RA and osteoarthritis.	19824913
Inflammation	Altered Intercellular Communication	MRI of the AC joint showed inflammation and erosion with joint fluid.	19826815
Inflammation	Altered Intercellular Communication	Significant contrast enhancement was noted at the SC joint due to inflammation.	19826815
Inflammation, Enteral	Altered Intercellular Communication	Enteric fluids produced by enterocutaneous fistulae can cause severe inflammation in the surrounding skin.	19827481
Inflammation	Altered Intercellular Communication	Endoscopic signs of inflammation, its extent and severity were recorded.	19827530
Inflammation, Urinary tract infection	Altered Intercellular Communication	Blood examination and urinalysis showed neither systemic inflammation nor urinary tract infection.	19827624
Inflammation	Altered Intercellular Communication	In addition, the results strongly suggest that the cytokines released by activated lymphocytes at sites of inflammation may play a part in up-regulating CD81 expression.	19828092
Hepatic necrosis, Inflammation, Fatty degeneration	Altered Intercellular Communication	In the liver, hepatic necrosis was observed with fatty degeneration accompanied by inflammation.	19828353
Shock, Inflammation, Shock, Hemorrhagic	Altered Intercellular Communication	Excessive autolytic inflammation accompanied by dysfunction of "shock organs" is recognized as arising from hemorrhagic shock due to the promotion of endovascular recruitment of neutrophils.	19828355
Inflammation, Inflammatory disorder, Metabolic Syndrome X	Altered Intercellular Communication	This suggests that replacement of dietary SFA with MUFA could prevent adipose tissue inflammation and may reduce the risk of inflammation-related diseases such as metabolic syndrome.	19828712
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Upon activation by calcineurin, the nuclear factor of activated T-cells (NFAT) translocates to the nucleus and guides the transcription of numerous molecules involved in inflammation and Ca(2+) dysregulation, both of which are prominent features of Alzheimer's disease (AD).	19828810
Inflammation, Bladder Neoplasm, Necrosis	Altered Intercellular Communication	Perivesical inflammation and necrosis due to mitomycin C instillation after transurethral resection of bladder tumor: we must be vigilant!	19829042
Inflammation, glucose metabolism, Hyperglycemia, Electrocardiogram: myocardial infarction (finding), Diabetes Mellitus, Myocardial	Altered Intercellular Communication	In 175 consecutive patients without previously known diabetes and with ST elevation myocardial infarction treated with primary angioplasty, we evaluated the relation between acute and chronic glucose dysmetabolism and early and late mortality and the relation between hyperglycemia and extension of myocardial damage [creatine phosphokinase-MB (CPK-MB), troponin I levels, ejection fraction], inflammation (leukocyte count, erythrocyte sedimentation rate, C-reactive protein) and prognostic biohumoral markers [N-terminal brain natriuretic peptide (NT-proBNP) and lactic acid].	19829142
Inflammation, Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome, Hypertrophy	Altered Intercellular Communication	Spinal specimens obtained surgically showed nonspecific inflammation and fibrous hypertrophy of the bone marrow, confirming a diagnosis of the SAPHO syndrome.	19830381
Primary malignant neoplasm	Altered Intercellular Communication	HsCRP increased in response to RT for H&N cancer as a sign of irradiation-induced inflammation.	19830461
Inflammation, Prostate carcinoma	Altered Intercellular Communication	African American men have the highest rates of prostate cancer worldwide, and immunogenetic studies suggest that people of African descent have increased susceptibility to diseases of inflammation.	19830784
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Since genetic susceptibility is an etiological factor in prostate cancer, we hypothesize that sequence variants in the promoter region of the CD14 gene that regulate inflammation may modify individual susceptibility to this disease.	19830784
Inflammation, Periodontal Diseases, Gingival Hemorrhage, Dental Plaque, Hematological Disease	Altered Intercellular Communication	Oral hygiene motivation and dental plaque control is crucial in order to prevent gingival bleeding, inflammation and severe periodontal diseases in patients with haematologic disorders.	19832917
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Risk factors included luminal stenosis, age, smoking, diabetes, calcium-phosphorus product, inflammation, and kidney function.	19833908
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Fluorodeoxyglucose (FDG) uptake in joint lesions in patients with rheumatoid arthritis (RA) reportedly represents the degree of synovial inflammation.	19834653
Refractory anemias, Inflammation	Altered Intercellular Communication	Whole-body FDG-PET/CT delineated large-joint lesions in patients with RA, and the metabolic activity of inflammation was accurately overlaid on the joint anatomy.	19834653
Inflammation, Cardiac dysfunction	Altered Intercellular Communication	In addition, TnTc levels are significantly associated with cardiac dysfunction (p < 0.05) and inflammation (p 0.01).	19835288
Inflammation, Cardiac dysfunction, Ventricular Dysfunction, Left	Altered Intercellular Communication	The causes of elevated cTnT levels in hemodialysis patients was multiple: cardiac dysfunction, left ventricular dysfunction and inflammation.	19835288
Inflammation, Chronic inflammatory disorder	Altered Intercellular Communication	Given this role for proteasome in inflammation resolution, restoration of proteasome function may constitute a novel mechanism for intervening in chronic inflammatory diseases.	19835847
Inflammation, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	Given that inflammation (characterized here by CRP) is an important factor in the development of atherosclerosis and cardiovascular disease, these results suggest a role for OH-PAHs in the progression of atherosclerosis.	19836015
Presenile dementia, Inflammation	Altered Intercellular Communication	Inflammation is believed to play a pivotal role in dementia, but its role is still unclear.	19836632
Presenile dementia, Inflammation	Altered Intercellular Communication	The aim of our study was to analyze the interplay among markers of inflammation, such as fibrinogen and high CRP levels, and dementia.	19836632
Presenile dementia, Inflammation	Altered Intercellular Communication	First, we performed a cross-sectional study comparing markers of inflammation between 99 patients affected by dementia (mean age: 83.0+/-0.6 years) and 99 controls (mean age: 83.9+/-0.7 years).	19836632
Inflammation, Dementia, Vascular, Presenile dementia, "Alzheimers Disease", Data types - Address, VAD I protocol	Altered Intercellular Communication	Then, we analyzed the relationship between inflammation and dementia in the same population composed by 34 Alzheimer's disease (AD) patients (mean age: 83.4+/-0.8 years), 64 vascular dementia (VaD) patients (mean age: 82.7+0.8 years) and 99 controls.	19836632
Inflammation, Data types - Address	Altered Intercellular Communication	The study suggests that inflammation may have a pathogenetic role in AD.	19836632
Airway structure, Nasal Polyps	Altered Intercellular Communication	Respiratory symptoms without BHR were associated with eosinophilic airway inflammation and increased ENO only in patients with nasal polyps.	19837820
Inflammation, Graft-vs-Host Disease	Altered Intercellular Communication	T-regs were positively correlated with both inflammation and aGVHD grade.	19838066
Inflammation, Graft-vs-Host Disease	Altered Intercellular Communication	Twelve cases with low T-regs had mild inflammation and lower grades of aGVHD and 6 cases with high T-regs had dense inflammatory infiltrate and higher grades of aGVHD.	19838066
Inflammation, Graft-vs-Host Disease	Altered Intercellular Communication	In aGVHD of the skin, T-regs increased with the degree of inflammation and GVHD grade.	19838066
Inflammation	Altered Intercellular Communication	Interleukins are important mediators and modulators of inflammation.	19838108
Granulomatous inflammation	Altered Intercellular Communication	On physical examination, hyperpigmented, papular lesions were noticed; biopsy of the skin of his right elbow showed granulomatous inflammation.	19838983
Inflammation	Altered Intercellular Communication	In patients with intact cag-PAI, acute on chronic inflammation was present in 25 (81%) and was more common than chronic inflammation (P=0.013).	19839224
Inflammation	Altered Intercellular Communication	The cagAP region was significantly associated with GC (n=12 [80%], P<0.001) and GU (n=9 [82%], P=0.001) compared to NUD (n=24 [30%] and with significant acute on chronic inflammation (n=40 [80%], P=0.007).	19839224
Necrotizing granulomatous inflammation, Granulomatosis with polyangiitis, physiopathological	Altered Intercellular Communication	Necrotizing granulomatous inflammation of the upper respiratory tract is one of the hallmarks of Wegener's granulomatosis (WG), which may explain the reason for olfactory dysfunction in WG.	19839246
Granulomatous inflammation, Failure (biologic function)	Altered Intercellular Communication	In general, a cautious attitude prevails out of fear of complications or failure due to the underlying granulomatous inflammation.	19839261
Inflammation, Malnutrition	Altered Intercellular Communication	Because malnutrition and inflammation can cause high mortality in MHD patients, preserving RRF is important for these patients.	19839818
Inflammation, hepcidin, Prohepcidin	Altered Intercellular Communication	Hyporesponsiveness to erythropoietin therapy in hemodialyzed patients: potential role of prohepcidin, hepcidin, and inflammation.	19839848
Inflammation, Overweight	Altered Intercellular Communication	Inflammation and overweight in peritoneal dialysis: is there an association?	19839849
Inflammation	Altered Intercellular Communication	Our findings confirm the relationship between inflammation, body fat, and immunocompetence, which may be superimposed potentializing the inflammatory status.	19839849
Inflammation	Altered Intercellular Communication	The degree of inflammation (NOSPECS Class 2) decreased (P<0.001).	19839884
Autoimmune Diseases, Blepharitis, Thyroid associated opthalmopathies	Altered Intercellular Communication	Can autoimmunity against calsequestrin explain the eye and eyelid muscle inflammation of thyroid eye disease?	19839885
Inflammation, Hemorrhage	Altered Intercellular Communication	A biopsy from an elevated conjunctival area showed a brown pigmentation to be haemosiderin and haemogranulomatous inflammation most probably due to recurrent subconjunctival haemorrhage.	19839907
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Markers of inflammation have been associated with risk of myocardial infarction (MI).	19841382
Interstitial lung fibrosis, Inflammation	Altered Intercellular Communication	Chemokine receptors in a regulation of interstitial lung fibrosis and inflammation.	19842835
Airway structure	Altered Intercellular Communication	Neutrophils may contribute significantly to airway inflammation in certain asthma subtypes.	19842845
Necrotizing inflammation	Altered Intercellular Communication	Necrotizing inflammation is more often seen in patients with low CD4 counts.	19843144
Inflammation, Metabolic Syndrome X, Diabetes Mellitus, Heart Diseases, Overweight	Altered Intercellular Communication	The ability to reduce inflammation in overweight and obese individuals may be valuable in preventing the progression to metabolic syndrome with associated risks for heart disease and diabetes.	19843321
Airway structure, Bronchiectasis	Altered Intercellular Communication	Chest CT revealed diffuse airway inflammation with bronchiectasis.	19843409
Inflammation, Pain, Postoperative	Altered Intercellular Communication	Although opioids are the mainstay of inpatient postoperative pain management, they do not block inflammation.	19843482
Tears body substance, Inflammatory abnormality of the eye, Disorder of eye	Altered Intercellular Communication	Ocular surface inflammation, and nerve growth factor level in tears in active thyroid-associated ophthalmopathy.	19844736
Inflammatory abnormality of the eye	Altered Intercellular Communication	Tear NGF may have a specific role in ocular surface inflammation, which protects against ocular surface damage in patients with active TAO.	19844736
Inflammation, Dental Leakage	Altered Intercellular Communication	The pelvic drain was always effective in allowing the early diagnosis of leakages and limiting the spread of peritoneal inflammation.	19845262
Inflammation, Urticaria	Altered Intercellular Communication	Coagulation/fibrinolysis and inflammation markers are associated with disease activity in patients with chronic urticaria.	19845571
Inflammation, curcumin	Altered Intercellular Communication	In this article, we studied the coagulation/fibrinolysis and inflammation markers and their relationship to disease activity in patients with CU.	19845571
Eosinophilic disorder, Inflammation	Altered Intercellular Communication	Eosinophilia is an established marker of asthma-related inflammation.	19846286
Inflammation	Altered Intercellular Communication	The high expression of MCP-1 and IL-8 chemokines suggest that macrophages and T cells may stimulate inflammation of the CNS in MFS.	19846311
Inflammation, Negative Regulation of Cell Cycle	Altered Intercellular Communication	Global gene expression analyses of tetraploid endothelial cells revealed a dysfunctional phenotype characterized by a cell cycle arrest profile (decreased CCNE2/A2, RBL1, BUB1B; increased CDKN1A) and increased expression of genes involved in inflammation (IL32, TNFRSF21/10C, PTGS1) and extracellular matrix remodeling (COL5A1, FN1, MMP10/14).	19846757
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	These increases were not found in PP.Rhythmical behavior of blood flow in malignant tumors is totally different from that in regions with inflammation.	19847053
Diabetic Angiopathies, Chronic Kidney Diseases	Altered Intercellular Communication	These findings need to be underlined if we consider that chronic renal failure is an inflammatory condition and this research furtherly supports literature data regarding the role of activated leukocytes in the development of the vascular complications.	19847059
Inflammation, Periodontitis, Alveolar Bone Loss, Cerebrovascular accident	Altered Intercellular Communication	We evaluated incidence of cerebrovascular events consistent with stroke or transient ischemic attack in relation to mean radiographic alveolar bone loss (a measure of periodontitis history) and cumulative periodontal probing depth (a measure of current periodontal inflammation).	19847898
Cerebrovascular Disorders	Altered Intercellular Communication	These results support an association between history of periodontitis-but not current periodontal inflammation-and incidence of cerebrovascular disease in men, independent of established cardiovascular risk factors, particularly among men aged <65 years.	19847898
Communicable Diseases, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	CXCR3-associated chemokines CXCL9-CXCL11 promote histologic progression in chronic hepatitis C virus (HCV) infection, as indicated by elevated intrahepatic levels of messenger RNA in patients with advanced inflammation and fibrosis.	19848607
Fibrosis Assessment, Intrahepatic Route of Drug Administration	Altered Intercellular Communication	Expression of all 3 chemokines, when analyzed as a group, was significantly associated with intrahepatic inflammation and fibrosis.	19848607
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Plasma levels of CXCL10 were significantly elevated in patients with advanced fibrosis, whereas CXCL9 levels were significantly elevated in patients with advanced inflammation.	19848607
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	By proportional odds multivariate modeling, we observed an association between fibrosis and CXCL10 (P< .002) as well as between fibrosis and inflammation (P<.001).	19848607
Dermatitis, Atopic, Inflammation, Data types - Address	Altered Intercellular Communication	Background A significant proportion of young children with atopic dermatitis (AD) is sensitized to microbial allergens, which play a potential role in the pathogenesis of AD inflammation.	19849698
Diastolic dysfunction, Inflammation	Altered Intercellular Communication	This study demonstrates progressive increases in markers of collagen turnover and inflammation in HFPSF with diastolic dysfunction.	19850207
Inflammation, Prediabetes syndrome, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Gender differences in adiponectin and low-grade inflammation among individuals with normal glucose tolerance, prediabetes, and type 2 diabetes.	19850242
Inflammation, Restenosis	Altered Intercellular Communication	Because inflammation plays a key role in restenosis, pimecrolimus, an anti-inflammatory drug, might reduce restenosis without adversely affecting re-endothelialization.	19850264
Inflammation, Neutrophilia (finding)	Altered Intercellular Communication	Pivotal Advance: Pharmacological manipulation of inflammation resolution during spontaneously resolving tissue neutrophilia in the zebrafish.	19850882
Inflammation, Thrombosis, Primary malignant neoplasm	Altered Intercellular Communication	Prostanoids play a critical role in clinical areas such as inflammation, thrombosis, immune response, and cancer.	19850905
Inflammation, Dilated Cardiomyopathy Pathway, Heart failure	Altered Intercellular Communication	Using a Cre/loxP system, we disrupted the Nemo gene in a cardiomyocyte-specific manner in the heart, which simulated gene expression changes underlying human heart failure and caused adult-onset dilated cardiomyopathy accompanied by inflammation and apoptosis.	19850942
Inflammation, Atherosclerosis	Altered Intercellular Communication	The chemokine and adhesion molecule fractalkine and its receptor CX(3)CR1 have emerged as interesting regulators in inflammation and related atherosclerosis.	19851523
Inflammation, Postprandial hyperlactemia	Altered Intercellular Communication	Postprandial hyperlipemia may influence inflammation; thus, we investigated fractalkine levels four and eight hours after inducing postprandial hyperlipemia.	19851523
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	The presence of five pathogens was assessed, together with a possible correlation of the total pathogen burden on inflammation and (auto)immunity in aortic stenosis (AS) and degenerative aortic valve bioprosthesis (BP).	19852145
Inflammation, Nucleolar Fibrillar Material	Altered Intercellular Communication	In the majority of degenerative aortic valves, specific pathogens, inflammation and immunity were localized predominantly in the fibrosa of AS patients, and in superficial regions of the BP.	19852145
Inflammation	Altered Intercellular Communication	The presence of inflammation and the duration of dialysis treatment contribute to this complication.	19852148
Inflammation, Congestion, Edema	Altered Intercellular Communication	Archival nasal tissue samples were collected and examined by light microscopy: the number of goblet cells was counted, and the degree of inflammation, congestion, and edema was graded as mild, moderate, or severe.	19852553
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is characterized by high cardiovascular (CV) mortality, which has been related to systemic inflammation.	19852912
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Previous studies have demonstrated increased levels of serum markers of systemic inflammation and immune system function among individuals with depressive symptoms.	19853625
Airway structure, Sleep Apnea, Obstructive, Traumatic injury, Osage language	Altered Intercellular Communication	Hypoxia and snoring-related mechanical trauma contribute to airway inflammation in obstructive sleep apnoea (OSA).	19854036
Airway structure, Osage language	Altered Intercellular Communication	Increased exhaled nitric oxide (FENO), an airway inflammation marker, has been reported in OSA patients.	19854036
Pharyngitis, Osage language	Altered Intercellular Communication	We propose the measure of NO in the oral cavity (oNO) as marker of oropharyngeal inflammation in OSA.	19854036
Inflammation, Hypoxemia, Osage language	Altered Intercellular Communication	The finding that oral NO is increased in OSA and is related to upper airway obstructive episodes and to hypoxemia severity, strengthens the clinical and pathogenic role of oral inflammation in OSA.	19854036
Airway structure, ARCN1 gene, Pulmonary Emphysema	Altered Intercellular Communication	Systemic and airway inflammation and the presence of emphysema in patients with COPD.	19854037
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Aging is associated with increasing levels of systemic inflammation and oxidative stress, both of which contribute to the progression of cardiovascular disease.	19854376
Inflammation, Aggressive behavior, Pneumonitis, Blood Coagulation Disorders	Altered Intercellular Communication	ALI/ARDS is the response of the lung to a local or systemic aggression, resulting in local inflammation and coagulation disorders, which lead to increased inflammatory pulmonary edema.	19854543
Inflammation, Systemic disease	Altered Intercellular Communication	This study suggests that CRP is not a predictive marker of inflammation and peripheral endothelial dysfunction in XFS, which is accepted as a systemic disorder.	19855290
Communicable Diseases, Inflammation, Leukocytosis	Altered Intercellular Communication	Additional examinations revealed the following markers of inflammation: leukocytosis (11 G/I) with normal level of eosinophils, CRP > 0.6 mg/I, ESR 120 mm/h, and IgG 20 g/l, without any source of infection.	19856878
Inflammation, Venous Thromboembolism, vinyltriethoxysilane	Altered Intercellular Communication	Elevated platelet count might reflect increased inflammation as an etiological factor for venous thromboembolism (VTE).	19857046
Inflammation, vinyltriethoxysilane, Fatigue	Altered Intercellular Communication	Poor sleep, fatigue, and exhaustion are all associated with inflammation and are also common sequelae of chronic psychological stress that previously predicted increased risk of VTE.	19857046
Papillary thyroid carcinoma, Laryngeal Squamous Cell Carcinoma, Necrotizing, Squamous cell carcinoma, metastatic	Altered Intercellular Communication	Incidental papillary thyroid carcinoma and necrotizing granulomatous inflammation were found in addition to squamous cell carcinoma metastasis in the pathological study of the neck dissection specimen in a 70-year-old male patient with laryngeal squamous cell carcinoma.	19857198
Inflammation, Endothelial dysfunction, Hyperuricemia	Altered Intercellular Communication	Hyperuricemia is a mediator of endothelial dysfunction and inflammation in renal allograft recipients.	19857674
Proteinuria, Inflammation, Diabetes Mellitus, Abnormal renal function, Obesity	Altered Intercellular Communication	Exclusion criteria were abnormal renal function, proteinuria, diabetes mellitus, obesity, and inflammation.	19857674
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Concentrations of plasma resistin, CD146, and soluble vascular cell adhesion molecule-1 (sVCAM-1), which are markers of endothelial dysfunction and inflammation, were assessed in both groups.	19857674
Inflammation, Endothelial dysfunction, Hyperuricemia	Altered Intercellular Communication	Hyperuricemia mediates endothelial dysfunction and inflammation and via this pathway, possibly contributes to chronic allograft injury and cardiovascular events in renal allograft recipients.	19857674
Inflammation, Cardiac Arrhythmia, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Relationship of indices of inflammation and thrombogenesis to arrhythmia burden in paroxysmal atrial fibrillation.	19858230
Inflammation, Alveolar Epithelial Cells	Altered Intercellular Communication	The best performing biomarkers were the neutrophil chemotactic factor, IL-8, and SP-D, a product of alveolar type 2 cells, supporting the concept that acute inflammation and alveolar epithelial injury are important pathogenetic pathways in human ALI/ARDS.	19858233
Inflammation, Alveolar Epithelial Cells	Altered Intercellular Communication	From a pathogenesis perspective, the degree of acute inflammation and alveolar epithelial injury are highly associated with the outcome of human ALI/ARDS.	19858233
Inflammation, Myopathy	Altered Intercellular Communication	Muscle biopsy demonstrated severe generalised necrotising myopathy in the notable absence of inflammation.	19859711
Inflammation, Giant Cells, Foreign-Body	Altered Intercellular Communication	Histological examination showed foreign body material surrounded by chronic inflammation, foreign body-type multinucleated giant cells, extravasated red blood cells and fibroblastic proliferation.	19860134
Inflammation, Abdominal Abscess	Altered Intercellular Communication	Because severe intraperitoneal inflammation was observed, ilectomy was changed to drainage of intra-abdominal abscess.	19860242
Cholecystitis, Biliary calculi	Altered Intercellular Communication	Sulbactam/cefoperazone was started under a tentative diagnosis of gall bladder inflammation with gallstones based on ultrasonographic findings.	19860259
Inflammation, Necrosis	Altered Intercellular Communication	Histopathologic examination showed acinar cell necrosis and dense inflammation of the affected minor salivary glands in the second biopsy.	19860638
Inflammation	Altered Intercellular Communication	Telomere length reflects lifetime cumulative oxidative stress from environmental exposures, such as cigarette smoking and chronic inflammation.	19861514
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	Chronic inflammation has been implicated in the etiology of gastric cancer.	19861525
Inflammation	Altered Intercellular Communication	Prostaglandin E(2) (PGE(2)) is one of the major end-products of the cyclooxygenase-2 pathway, an enzyme that is an important mediator of inflammation.	19861525
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	Our findings suggest that higher levels of urinary PGE-M, a marker of inflammation, may be associated with gastric cancer risk.	19861525
Communicable Diseases, Inflammation, Traumatic injury, Neoplasms	Altered Intercellular Communication	The secondary acquired obstructions may result from infection, inflammation, neoplasm, trauma or mechanical causes.	19861752
Heart Diseases, HD Term Type, Inflammation	Altered Intercellular Communication	Heart disease (HD) can stress the alveolar blood-gas barrier, resulting in parenchymal inflammation and remodeling.	19862572
Inflammation, Fibrosis Assessment, viral hepatitis E infection	Altered Intercellular Communication	To evaluate the clinical practical value of apparent diffusion coefficient (ADC) measurements based on diffusion-weighted MR imaging (DWI) for quantification of liver fibrosis and inflammation for hepatitis viral infection.	19862980
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The inflammation grades and fibrosis stages were evaluated histologically by biopsy.	19862980
Inflammation	Altered Intercellular Communication	There was weak to moderate negative correlation between ADCs and inflammation grade.	19862980
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The DWI measurement of hepatic ADC can be used to quantify liver fibrosis and inflammation.	19862980
Inflammation, Lung Diseases, Obstructive	Altered Intercellular Communication	Inflammation has been identified as an important factor for disease exacerbation in obstructive lung disease.	19863191
hearing impairment, Inflammation	Altered Intercellular Communication	The pure-tone audiogram (PTA) indicated mild hearing loss in the right ear, and her hearing continued to deteriorate despite recovery from inflammation.	19864094
Pneumonitis	Altered Intercellular Communication	Vaccination to induce antibodies blocking the CX3C-CX3CR1 interaction of respiratory syncytial virus G protein reduces pulmonary inflammation and virus replication in mice.	19864390
Weight decreased, Pneumonitis	Altered Intercellular Communication	The results show that mice vaccinated with G protein peptides or polypeptides containing the CX3C motif generate antibodies that inhibit G protein CX3C-CX3CR1 binding and chemotaxis, reduce lung virus titers, and prevent body weight loss and pulmonary inflammation.	19864390
Inflammation	Altered Intercellular Communication	IMAT was primarily related to age and total body adiposity; subclinical inflammation in fat significantly contributes to IMAT.	19864639
Inflammation	Altered Intercellular Communication	Both patients had active H. pylori-related inflammation.	19864985
Inflammation, Central Nervous System Agents	Altered Intercellular Communication	In animals, central nervous system inflammation increases drug accumulation in the brain partly due to a loss of central nervous system drug efflux transporter function at the blood-brain barrier.	19865006
Inflammation, Brain Injuries	Altered Intercellular Communication	Our results suggest that central nervous system inflammation following acute brain injury may selectively inhibit the activity of specific drug efflux transporters within the blood-brain barrier.	19865006
Presenile dementia, Impaired cognition	Altered Intercellular Communication	Our results indicate that: i) consistent with recent neuropathological findings, gene expression changes associated with cognitive impairment in oldest-old persons are distinct from those in cognitively impaired youngest-old persons; ii) transcripts affected in young-old subjects with dementia participate in biological pathways related to synaptic function and neurotransmission while transcripts affected in oldest-old subjects with dementia are associated with immune/inflammatory function; iii) upregulation of immune response genes in cognitively intact oldest-old subjects and their subsequent downregulation in dementia suggests a potential protective role of the brain immune-associated system against dementia in the oldest-old; iv) consistent with gene expression profiles, protein expression of several selected genes associated with the inflammatory/immune system in inferior temporal cortex is significantly increased in cognitively intact oldest-old persons relative to cognitively intact young-old persons, but impaired in cognitively compromised oldest-old persons relative to cognitively intact oldest-old controls.	19865478
Presenile dementia	Altered Intercellular Communication	These results suggest that disruption of the robust immune homeostasis that is characteristic of oldest-old individuals who avoided dementia may be directly associated with dementia in the oldest-old and contrast with the synaptic and neurotransmitter system failures that typify dementia in younger old persons.	19865478
Orbital Pseudotumor	Altered Intercellular Communication	Thirty to sixty percent of patients also suffer from orbital inflammation.	19865824
Inflammation, Silicosis, Pulmonary Fibrosis	Altered Intercellular Communication	Chronic occupational exposure to tiny particles of silicon dioxide can stimulate parenchymal inflammation, collagen synthesis and, ultimately pulmonary fibrosis called silicosis.	19866335
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Therefore, we hypothesized that leukocytes associated with either acute or chronic inflammation attracted to the prostate consequent to aging or tumorigenesis may promote the abnormal cellular proliferation associated with BPH and PCa.	19866464
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is involved in the development of atherosclerosis.	19874552
Inflammation, Vascular Diseases, Atherosclerosis	Altered Intercellular Communication	The CC chemokine receptor 5 (CCR5) initiates chemotaxis and modulates the inflammation secondary to atherosclerosis and related vascular diseases.	19874552
methyldopa, Retinitis, GDC Disease Response Terminology	Altered Intercellular Communication	Activation of the canonical Wnt pathway is sufficient to induce retinal inflammation and oxidative stress and plays a pathogenic role in AMD and DR.	19875668
Airway structure, Inflammation, Bronchial Hyperreactivity	Altered Intercellular Communication	Reduction of tumstatin in asthmatic airways contributes to angiogenesis, inflammation, and hyperresponsiveness.	19875687
Carcinoma of lung	Altered Intercellular Communication	This suggests that hormonal influence may not be an important factor to account for the high prevalence of lung cancer among the East-Asian women.	19875972
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	In per-patient analysis, the accuracy of green mucosa in patients with activity, inflammation, atrophy and intestinal metaplasia was 64, 93, 88 and 81%, respectively.	19876586
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	In per-biopsy analysis, the accuracy for activity, inflammation, atrophy and intestinal metaplasia was 55, 62, 76 and 76%, respectively.	19876586
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	Green areas in the gastric body exhibited more inflammation (p < 0.001), atrophy (p < 0.001) and intestinal metaplasia (p < 0.001), whereas purple areas rarely contained atrophy or intestinal metaplasia.	19876586
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor alpha was recently implicated as an important mediator of communication between the peripheral and cerebral immune systems in an animal model of chronic inflammation.	19877035
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The purpose of this study was to examine by proton magnetic resonance spectroscopy ((1)H-MRS) the influence of inflammation on cerebral metabolism in patients with rheumatoid arthritis (RA).	19877035
Refractory anemias, Inflammation	Altered Intercellular Communication	Our data show that systemic inflammation in RA is associated with metabolic changes in the brain.	19877035
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The goal of this study was to characterize IFP tissue in obese OA patients and to compare its features with thigh subcutaneous AT to determine whether the IFP contributes to local inflammation in knee OA via production of specific cytokines.	19877065
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Our results indicate that the IFP cytokine profile typically found in OA patients could play a role in paracrine inflammation via the local production of IL-6/sIL-6R and that such a profile might contribute to damage in adjacent cartilage.	19877065
Inflammation	Altered Intercellular Communication	Synovial fluid COMP levels correlated strongly with 2 indicators of knee joint inflammation: early-phase bone scintigraphic findings and synovial fluid volume.	19877068
Inflammation, Atherosclerosis, Refractory anemias, Coronary Arteriosclerosis, Tumor necrosis	Altered Intercellular Communication	We hypothesized that mediators of inflammation associated with atherosclerosis in other populations (interleukin-6 [IL-6], tumor necrosis factor alpha [TNFalpha], serum amyloid A [SAA], vascular endothelial growth factor, neutrophil count, IL-1alpha, E-selectin, intercellular adhesion molecule 1 [ICAM-1], myeloperoxidase [MPO], matrix metalloproteinase 9, and vascular cell adhesion molecule 1) would be increased and associated with the severity of coronary atherosclerosis in patients with RA.	19877084
Inflammation, Panuveitis, Visual, Unspecified visual loss	Altered Intercellular Communication	The risk factors for severe visual loss (< or = 0.1) are panuveitis, bilateral inflammation, prolonged visual reduction and a significant number of relapses.	19877547
Crohn Disease, Osteoporosis	Altered Intercellular Communication	The highest osteoporosis risk was seen in patients with a cumulative 10 - 35 g corticosteroid dose and could be due to both steroid inefficiency in reducing Crohn's disease inflammation as well as the cumulative drug dose and it's adverse effect on patients.	19877750
Cataract, Inflammation	Altered Intercellular Communication	Evaluation of anterior-segment inflammation and retinal thickness change following cataract surgery.	19878107
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Adipose tissue-derived inflammation may contribute to metabolic alterations and eventually to the metabolic syndrome (MetS).	19878507
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Non-obese and obese individuals who develop an intense pro-inflammatory state may be more prone to develop the MetS than those with lower levels of inflammation.	19878507
Inflammation, Pathology	Altered Intercellular Communication	Different patterns in telomere length from PBL are evidenced in rheumatologic pathologies, possibly dependent on the presence or absence of chronic systemic inflammation.	19879280
Inflammation, Primary malignant neoplasm, Fatigue	Altered Intercellular Communication	Impact of medical Qigong on quality of life, fatigue, mood and inflammation in cancer patients: a randomized controlled trial.	19880433
Inflammation	Altered Intercellular Communication	It may also produce physical benefits in the long term through reduced inflammation.	19880433
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The p38 mitogen-activated protein kinase (MAPK) signaling upregulates inflammation and is known to be increased in chronic obstructive pulmonary disease (COPD).	19880675
ARCN1 gene, Inflammation	Altered Intercellular Communication	SB-681323 is a potent p38 MAPK inhibitor that potentially suppresses inflammation in COPD.	19880675
Inflammation	Altered Intercellular Communication	The disease manifested as an increase in baseline ANC and reduced maturation time due to increased demand from the inflammation site.	19880676
Inflammation, Pancreatic Serous Neoplasm	Altered Intercellular Communication	Xanthogranulomatous inflammation of the peripancreatic region mimicking pancreatic cystic neoplasm.	19881238
Inflammation, Fibrosis Assessment, Parenchyma	Altered Intercellular Communication	Xanthogranulomatous inflammation (XGI) is histopathologically characterized by a marked proliferative fibrosis, parenchymal destruction, and infiltration of foamy histiocytes intermixed with other inflammatory cells.	19881238
Adenocarcinoma, Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Among others, adenocarcinoma was found in 28.5%, benign prostatic hyperplasia (BPH) alone in 43.3%, BPH with inflammation in 20.3% and inflammation alone in 4.2%.	19882057
Inflammation, Lung Abscess	Altered Intercellular Communication	Although the lung abscess resolved, the inflammation of the esophagus persisted.	19882320
Intraocular inflammation	Altered Intercellular Communication	It is associated with significant intraocular inflammation and can lead to poor visual outcome.	19882507
Narrow Band Imaging, Gastric mucosa, Inflammation	Altered Intercellular Communication	Staining intensity of gastric and duodenal mucosa in the NBI regime was shown to correlate with the degree of inflammation.	19882880
Rupture, Arterial aneurysm, Hemorrhage	Altered Intercellular Communication	Inflammation of the vessels can result in the development of arterial aneurysms with a potential risk of rupture or bleeding.	19884215
Inflammation, Lupus Erythematosus	Altered Intercellular Communication	It is possible that the expression of soluble HLA-G in systemic lupus erythematosus is enhanced as part of a mechanism to try to restore the tolerance process towards auto-antigens and to counteract inflammation.	19884219
Acute heart failure	Altered Intercellular Communication	Serial measurements of neurohormones have been shown to improve prognostication in the setting of acute heart failure (HF) or chronic HF without therapeutic intervention.	19884490
Inflammation, ALZHEIMER DISEASE 2	Altered Intercellular Communication	Vascular factors and markers of inflammation in offspring with a parental history of late-onset Alzheimer disease.	19884614
Inflammation	Altered Intercellular Communication	Amyloid pathology, vascular factors, and inflammation are postulated to be involved in its pathogenesis, but causality has not been established unequivocally.	19884614
Inflammation	Altered Intercellular Communication	The APOE epsilon4 genotype, vascular factors, production capacity of pro- and anti-inflammatory cytokines upon stimulation with lipopolysaccharide, and circulating markers of inflammation.	19884614
Inflammation	Altered Intercellular Communication	Black carbon is associated with markers of endothelial function and inflammation.	19884647
Inflammation, Specimen Type - Fistula	Altered Intercellular Communication	Such a longstanding inflammation of the fistula might have been a possible cause of the development of IMT in this case.	19885321
Inflammation, Neoplasms	Altered Intercellular Communication	The tumor, which showed signs of inflammation, was located within the bone and the soft tissue.	19885857
Inflammation	Altered Intercellular Communication	The inflammatory reaction is characterized by increased circulatory levels of various indicators of the severity of inflammation.	19886071
Inflammation, Cardiovascular Diseases, Cerebrovascular accident	Altered Intercellular Communication	The determination of Lp-PLA2 should be used to predict patient risk of cardiovascular disease and stroke; it does provide additional risk of inflammation when used in conjunction with the traditional markers.	19886071
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Here we studied and characterized different peripheral blood (PB) regulatory T cell (Treg) subsets in rheumatoid arthritis (RA) patients and tested the hypothesis that changes in these cells can be linked to the degree of inflammation and relapsing/remission periods.	19886735
Refractory anemias, Inflammation	Altered Intercellular Communication	We show that most of these changes parallel the intensity of inflammation, with lowest or highest values in patients with moderately/very active disease compared to healthy controls and at times to patients with inactive RA.	19886735
Renal Insufficiency, Inflammation, Sepsis	Altered Intercellular Communication	A renal-specific over-expression of beta(2)-AR, resulting from gene delivery, appeared to modulate renal dysfunction and inflammation following sepsis by altering cAMP-PKA, CB-1 and CD14-TLR4-TNF-alpha pathways.	19887504
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy.	19887952
Dermatitis	Altered Intercellular Communication	These results show that mast cells express increased levels of PAR-2 in chronic skin inflammation.	19889021
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Histologic factors for gastric mucosal inflammation were graded according to the guidelines of the Updated Sydney system.	19889073
Intestinal metaplasia, Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Helicobacter pylori infection causes chronic gastric inflammation and intestinal metaplasia (IM), related with deregulation of Wnt pathway and over-expressions of COX-2, matrix metalloproteinase (MMP), and tissue inhibitors of matrix metalloproteinase (TIMP).	19889076
Inflammation, Epstein-Barr Virus Infections	Altered Intercellular Communication	Chronic inflammation, immune-modifying drugs and Epstein Barr virus infection may be implicated in the pathogenesis of this disease.	19889478
Inflammation, Immune System Diseases	Altered Intercellular Communication	Immune dysfunction, inflammation, and accelerated aging in patients on antiretroviral therapy.	19890183
Gastrointestinal Stromal Tumors, Aphthous Stomatitis, Inflammation, Crohn Disease	Altered Intercellular Communication	Pathological examination of the surgical specimen revealed a gastrointestinal stromal tumor as well as aphthous ulcerations and areas of inflammation, which were characteristic of Crohn's disease.	19891025
Vascular lesions, Inflammation, Pathology	Altered Intercellular Communication	The main pathologies detected on DBE were polyps (14%), vascular lesions (17.6%) and inflammation (12%).	19891231
Hyperlipidemia, Inflammation	Altered Intercellular Communication	Markedly increased percentage of AA in serum and erythrocyte membrane phospholipid in hyperlipidemic patients receiving gemfibrozil on Step-1 diet is especially important for physiological functions (inflammation, vascular tone, hemostasis etc.)	19893100
Pain Distress Question, Inflammation	Altered Intercellular Communication	A 30-year-old man presented pain and inflammation in the left epididymis.	19893140
Inflammation, Neoplasms	Altered Intercellular Communication	Mesothelial origin has been mentioned and inflammation has played some role in the development of these tumors.	19893140
Inflammation, Sleep Apnea, Obstructive, Hypertension, CTCAE, Osage language	Altered Intercellular Communication	Obstructive sleep apnea (OSA) is related to increased systemic inflammation and arterial hypertension.	19893310
Inflammation, Gingival Hemorrhage	Altered Intercellular Communication	Slight gingival inflammation was present in 78.5% and gingival bleeding following probing occurred in 53.3%.	19893958
Inflammation, Necrosis, Mucoepidermoid Carcinoma, Oncocytic metaplasia, Hyperplasia, Squamous metaplasia	Altered Intercellular Communication	The cytopathologic picture showed a quizzical mixture of necrosis and inflammation coupled to hyperplastic changes of the acinar cells, oncocytic metaplasia, and atypical squamous metaplasia of extreme degree simulating high-grade epidermoid- or mucoepidermoid carcinoma.	19894261
Inflammation, Asthma	Altered Intercellular Communication	Prostaglandin E2 and cysteinyl leukotriene concentrations in sputum: association with asthma severity and eosinophilic inflammation.	19895589
Asthma	Altered Intercellular Communication	Inflammation of the airways in asthma is associated with the production of cysteinyl leukotrienes (cysLT), prostaglandin (PG)E(2), 8-isoprostane, nitric oxide and other mediators.	19895589
Inflammation, Asthma	Altered Intercellular Communication	However, the relationship between asthma severity or eosinophilic inflammation and the concentrations of mediators in sputum is unclear.	19895589
Airway structure, Asthma	Altered Intercellular Communication	To assess sputum PGE(2), cysLT, 8-isoprostane and nitrate concentrations, as well as urinary leukotriene (LT)E(4) and 9alpha,11beta-prostaglandin (PG)F(2) concentrations, in patients with differing severities of asthma and eosinophilic or non-eosinophilic airway inflammation.	19895589
Airway structure, Asthma	Altered Intercellular Communication	Asthmatic patients were categorized into those with eosinophilic or non-eosinophilic airway inflammation.	19895589
Airway structure	Altered Intercellular Communication	Sputum PGE(2) concentrations were lower in patients with eosinophilic (1180 pg/mL) compared with non-eosinophilic airway inflammation (2520 pg/mL) (P=0.02).	19895589
Airway structure	Altered Intercellular Communication	In contrast, sputum cysLT and urinary LTE(4) concentrations were higher in those with eosinophilic airway inflammation (P<0.05).	19895589
Airway structure	Altered Intercellular Communication	A reduced PGE(2) to cysLT ratio in the airways may adversely affect lung function and contribute to persistence of symptoms and airway remodelling in patients with eosinophilic airway inflammation.	19895589
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Cigarette smoke is the main cause of chronic obstructive pulmonary disease (COPD), where it can contribute to the observed airway inflammation.	19897740
Hemorrhage, Hemorrhagic inflammation	Altered Intercellular Communication	Cystoscopy revealed bleeding from the bilateral ureteric orifices without hemorrhagic inflammation of the bladder.	19897850
Inflammation, Mediastinal Emphysema	Altered Intercellular Communication	Endoscopic muscle exposure during ESD is a significant risk factor for pneumomediastinum, which causes mild inflammation in the early post-ESD phase.	19899032
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Chronic low-grade inflammation is related to diabetes risk in population studies.	19900225
Inflammation, bone destruction	Altered Intercellular Communication	Thus, IL-23 appears to induce joint inflammation and bone destruction by stimulating RANKL expression in RA-FLS.	19900478
Lagophthalmos, Dryness of eye, Conjunctivitis, Failure (biologic function)	Altered Intercellular Communication	Scores of such risks as infrequent blinking, blink-related microtrauma, conjunctival inflammation, elevated intraocular pressure, dry eye, symblepharon, lagophthalmos, and previous KLAL or penetrating keratoplasty (PKP) failure were calculated and recorded before, during, and after KLAL.	19901207
Septicemic melioidosis, Sepsis, Inflammation, Infection	Altered Intercellular Communication	The majority of changes observed were common to both septicemic melioidosis and sepsis caused by other infections, including genes related to inflammation, interferon-related genes, neutrophils, cytotoxic cells, and T-cells.	19903332
Inflammation, Platelet aggregation test result	Altered Intercellular Communication	Inflammation and platelet aggregation and activation are key processes in the initiation of a cardiovascular event.	19903376
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Relations of dietary magnesium intake to biomarkers of inflammation and endothelial dysfunction in an ethnically diverse cohort of postmenopausal women.	19903755
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Although magnesium may favorably affect metabolic outcomes, few studies have investigated the role of magnesium intake in systemic inflammation and endothelial dysfunction in humans.	19903755
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	High magnesium intake is associated with lower concentrations of certain markers of systemic inflammation and endothelial dysfunction in postmenopausal women.	19903755
Inflammation	Altered Intercellular Communication	Microscopically, they were characterized as having normal lipocytes without lipoblasts or inflammation.	19904221
Inflammation	Altered Intercellular Communication	Chronic inflammation is the hallmark of the pathogenesis of Helicobacter pylori-induced gastric cancer.	19904747
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Interleukin (IL)-17A and IL-17F are inflammatory cytokines expressed by a novel subset of CD4+ Th cells and play critical function in inflammation and probably in cancer.	19904747
Refractory anemias, Inflammation	Altered Intercellular Communication	Emerging risk factors, markers of inflammation and prothrombotic state such as platelet size are believed to reflect activity of RA.	19906007
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	No studies have been addressed to the differences in inflammation kinetics between ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation myocardial infarction (NSTEMI).	19906505
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	The absence of significant correlations between inflammatory indexes and myocardial infarction in NSTEMI supports the hypothesis that a different pattern of inflammation occurs in these patients.	19906505
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is an inflammatory condition characterized by oxidative stress and the formation of volatile organic compounds (VOCs) secreted via the lungs.	19906520
Autoimmune Diseases, Inflammatory abnormality of the eye, Complication Aspects, Scleritis	Altered Intercellular Communication	Scleritis is a form of ocular inflammation frequently associated with systemic autoimmune disease and ocular complications.	19907295
Inflammation	Altered Intercellular Communication	Healing was characterized by a comfortable eye, minimal inflammation, and good cosmetic result.	19907303
Inflammation, Degenerative disorder	Altered Intercellular Communication	Chronic inflammation is involved in the pathogenesis of chronic age-associated, degenerative diseases.	19907653
Behcet Syndrome	Altered Intercellular Communication	Behcet's disease is a chronic inflammatory condition involving several organs, such as the skin, mucous membranes, eyes, joints, intestines, lungs and central nervous system.	19908040
Chronic lymphocytic inflammation, High-Frequency Microsatellite Instability, Neoplasms	Altered Intercellular Communication	BRAF mutation was associated with right-sided tumor location (p < 0.001), higher tumor grade (p = 0.029), absence of peritumoral lymphocytic inflammation (p = 0.026) and MSI-H (p < 0.001).	19908233
Inflammation	Altered Intercellular Communication	These findings suggest a link between low-grade inflammation and the presence of LVDD.	19909503
Cataract, Intraocular inflammation, Uveomeningoencephalitic Syndrome	Altered Intercellular Communication	Elevated serum IL-23 correlates with intraocular inflammation after cataract surgery in patients with Vogt-Koyanagi-Harada disease.	19910285
Cataract, Uveomeningoencephalitic Syndrome, Inflammation	Altered Intercellular Communication	Patients with Vogt-Koyanagi-Harada (VKH) disease are known to have severe inflammation after cataract surgery.	19910285
Inflammation, Uveomeningoencephalitic Syndrome	Altered Intercellular Communication	This study was designed to investigate the role of IL-17-producing T helper (Th17) cell-related pro-inflammatory cytokines on postoperative inflammation in VKH patients.	19910285
Uveomeningoencephalitic Syndrome, Uveitis	Altered Intercellular Communication	The data indicate that serum IL-23 levels are significantly elevated in VKH compared with control patients and are strongly associated with postoperative intraocular inflammation.	19910285
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	IL-13 also up-regulated surface expression of HLA-DR, CD80, CD40, and CD154 by conjunctival fibroblasts, suggesting a potential mechanism for fibroblast-T cell cross talk, via which fibroblasts may actively engage in perpetuating chronic inflammation and continued fibrosis.	19910508
Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation plays a key role in the pathogenesis of acute coronary syndromes (ACS).	19911351
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Thus, increased expression of 15-LOX-2 in macrophages in hypoxic atherosclerotic plaque may enhance inflammation and the recruitment of inflammatory cells.	19912316
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Moraxella catarrhalis acquisition, airway inflammation and protease-antiprotease balance in chronic obstructive pulmonary disease.	19912665
Airway structure	Altered Intercellular Communication	Little is known about the effects of colonization by M. catarrhalis on airway inflammation and protease-antiprotease balance, and how these changes compare to those seen during exacerbations.	19912665
ARCN1 gene, Colonization, Inflammatory disorder, Airway structure	Altered Intercellular Communication	Since COPD is a progressive inflammatory disease, elucidating the effects of bacterial colonization and exacerbation on airway inflammation is relevant to understanding disease progression in COPD.	19912665
Airway structure, ARCN1 gene, Colonization	Altered Intercellular Communication	Our aims were (1) Analyze changes in airway inflammation in colonization and exacerbation of COPD due to M. catarrhalis; (2) Explore protease-antiprotease balance in colonization and exacerbation due to M. catarrhalis.	19912665
ARCN1 gene, Colonization, Exacerbation, Airway structure	Altered Intercellular Communication	Our hypothesis were (1) Acquisition of a new strain of M. catarrhalis in COPD increases airway inflammation from baseline and alters the protease-antiprotease balance towards a more proteolytic environment; (2) These changes are greater during exacerbations associated with M. catarrhalis as compared to colonization.	19912665
ARCN1 gene, Colonization, Exacerbation, Airway structure	Altered Intercellular Communication	Acquisition of M. catarrhalis in COPD causes increased airway inflammation and worsening protease-antiprotease imbalance during exacerbations and also in colonization, even in the absence of increased symptoms.	19912665
Airway structure, Arthritis, Helminthiasis	Altered Intercellular Communication	IL-33 has recently been associated with immune responses to helminthic intestinal infections, airway inflammation and arthritis in animal models.	19913053
Inflammation, Calcinosis	Altered Intercellular Communication	Plaques were scored for the presence of calcification, intimal inflammation, and neovasculature on a 5-point scale.	19913444
Autoimmune Diseases, Inflammation, Thrombosis	Altered Intercellular Communication	Impact of intimal pathogen burden in acute coronary syndromes--correlation with inflammation, thrombosis, and autoimmunity.	19914090
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	A large body of evidence suggests the importance of inflammation and oxidative or nitrosative stress in Alzheimer's disease (AD) pathogenesis.	19914323
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Vaspin and omentin: new adipokines differentially regulated at the site of inflammation in rheumatoid arthritis.	19914904
Inflammation, Aneurysm, Mycotic	Altered Intercellular Communication	Although mycotic aneurysm with inflammation tissue usually interferes with surgical manipulation because of severe adhesion to the lung, semi-clamshell approach helped us perform all these procedures.	19914927
Inflammation, Atherosclerosis	Altered Intercellular Communication	Estrogen induces nitric oxide (NO) in the endothelium and appears to protect against inflammation and atherosclerosis.	19914929
Inflammation, Anemia, Vascular calcification	Altered Intercellular Communication	Higher free p-cresylsulphate levels (>0.051 mg/100 mL; median) were associated with mortality independently of well-known predictors of survival such as age, vascular calcification, anaemia and inflammation.	19914995
Inflammation, Kidney damage	Altered Intercellular Communication	C-reactive protein (CRP), a marker for inflammation, has been recently associated with early kidney damage.	19914996
Inflammation, Kidney damage	Altered Intercellular Communication	This suggests that inflammation may play a role in early kidney damage.	19914996
Inflammation, Discitis	Altered Intercellular Communication	Fungal spondylodiskitis (inflammation of intervertebral disk tissue and adjacent vertebrae) is rare, particularly in immunocompetent patients.	19915311
Inflammation	Altered Intercellular Communication	Serum TRAP 5a, on the other hand, has no relationship to bone metabolism but seems instead to be a measure of activated macrophages and chronic inflammation.	19915788
Airway structure, Asthma	Altered Intercellular Communication	Oncostatin M may link airway inflammation to remodeling in asthma.	19916861
Sample Size Calculation, Inflammation	Altered Intercellular Communication	These results suggest that anti-ATF-2 Ab is a new autoantibody in SSc and that it serves as a novel serological marker for inflammation and lung involvement in SSc.	19917156
Juvenile arthritis, Inflammation	Altered Intercellular Communication	Exposure to stagnant polluted air may be an environmental risk factor for JIA in young children, potentially triggered by pollution-induced pulmonary mediated inflammation.	19917177
Inflammation, Malnutrition, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Endothelial dysfunction (ED) is a common, early abnormality that predisposes patients to develop atherosclerosis and cardiovascular events; inflammation is associated with atherosclerosis and malnutrition.	19917360
Inflammation, Crypt abscess, Stenosis, Ulcer, Lobular Endocervical Glandular Hyperplasia, Crohn Disease	Altered Intercellular Communication	Subsequent laparoscopy led to the identification of severe, active Crohn disease with strictures, ulcers, crypt abscesses, pyloric metaplasia, and transmural inflammation.	19917475
Inflammation, Heart failure	Altered Intercellular Communication	We examined whether the antiinflammatory action of statins may be of benefit in heart failure, a state characterized by inflammation in which low cholesterol is associated with worse outcomes.	19917888
Inflammation	Altered Intercellular Communication	A punch biopsy showed granulomatous inflammation and associated PXE-like changes.	19917959
Pain Distress Question, Fatigue	Altered Intercellular Communication	Factor analysis identified Disease Activity Score-28 (DAS28) and swollen (SJC) and tender joint count (TJC) as a physician-inflammation factor, and patient global assessment, pain, Health Assessment Questionnaire, and fatigue as patient components.	19918042
Refractory anemias, Inflammation	Altered Intercellular Communication	IL-33 was produced mainly in inflamed joints; IL-33/ST2L signaling might play an important role in joint inflammation of human RA.	19918048
Inflammation, Neoplasms, Diverticular Diseases	Altered Intercellular Communication	Bowel preparation, polyps, angioectasias, diverticular disease, inflammation and neoplasm were also verified.	19918681
Communicable Diseases, Fibrosis Assessment, Hepatic inflammation, Hepatitis C	Altered Intercellular Communication	Association among Fas expression in leucocytes, serum Fas and Fas-ligand concentrations and hepatic inflammation and fibrosis in chronic hepatitis C. Replication of the hepatitis C virus (HCV) in peripheral blood mononuclear cells (PBMC) may impair immune functions and establish persistent infection.	19919570
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Fas expression on monocytes was lower in advanced stages of liver inflammation and fibrosis.	19919570
Inflammation, Ischemic stroke	Altered Intercellular Communication	Polymorphisms of G-572C and G-174C in the interleukin-6 (IL-6) promoter can affect both the transcription and secretion of IL-6 and may be involved in inflammation related to and the pathogenesis of ischemic stroke (IS).	19919828
Inflammation, Heart failure	Altered Intercellular Communication	Inflammation has been implicated in the pathogenesis of heart failure (HF), but knowledge about the production and role of inflammatory actors remains incomplete.	19919988
vascular inflammations	Altered Intercellular Communication	On the basis of its role in vascular inflammation, vascular proliferation, and matrix degradation, we hypothesized a role for the chemokine CXCL16 in the pathogenesis of myocardial remodeling and development of HF.	19919988
vascular inflammations, Dissection of aorta	Altered Intercellular Communication	An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice.	19920349
vascular inflammations, Aortic Aneurysm, Cardiovascular Diseases	Altered Intercellular Communication	Vascular inflammation contributes to cardiovascular diseases such as aortic aneurysm and dissection.	19920349
vascular inflammations	Altered Intercellular Communication	We have shown here that subcutaneous infusion of Ang II, a vasopressor known to promote vascular inflammation, into older C57BL/6J mice induced aortic production of the proinflammatory cytokine IL-6 and the monocyte chemoattractant MCP-1.	19920349
vascular inflammations	Altered Intercellular Communication	These results suggest that leukocyte-fibroblast interactions in the aortic adventitia potentiate IL-6 production, inducing local monocyte recruitment and activation, thereby promoting MCP-1 secretion, vascular inflammation, ECM remodeling, and aortic destabilization.	19920349
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Osteoarthritis (OA) is characterized by progressive cartilage degradation and secondary inflammation of the synovial membrane.	19922256
Inflammation, Thrombosis, ENL Protein, Arteritis, Erythema, Type 2 lepra reaction	Altered Intercellular Communication	Eight weeks after stopping her medications, she developed a severe and recalcitrant erythema (nodosum) leprosum (ENL) which presented histologically with thrombosed small veins and neutrophilic inflammation in fat septa, but without arteritis.	19922466
Inflammation, Heart failure	Altered Intercellular Communication	Although increasing evidence supports immune-mediated inflammation plays an important role in the pathophysiology of heart failure, little is known regarding the source and mechanism that trigger immune responses.	19923020
Gastroesophageal reflux disease, Chronic Obstructive Airway Disease, Chronic pain, Heart failure, Depression, CTCAE	Altered Intercellular Communication	46% had gastro-oesophageal reflux disease, 25% depression, 20% chronic airways disease or chronic pain and 15% also had heart failure or inflammation-pain.	19923032
Nephritis	Altered Intercellular Communication	Bradykinin and high glucose promote renal tubular inflammation.	19923143
Inflammation, Fever, CTCAE	Altered Intercellular Communication	After allogeneic stem cell transplantation, a 49-year-old man developed fever and inflammation at the site of a plant puncture on a finger.	19923491
Inflammation, Corneal Endothelial Cell Loss	Altered Intercellular Communication	High-volume priming of the CPB circuit with a modern balanced HES solution resulted in reduced inflammation, less endothelial damage, and fewer alterations in renal tubular integrity compared with an albumin-based priming.	19923501
Inflammation, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	The relationship between obstructive sleep apnea (OSA) and atherosclerosis-related inflammation has been poorly investigated, particularly focusing on functional responses of immune cells playing a key role in atherogenesis and in comparison with control groups with similar cardiovascular risk factors which are known to be themselves associated with inflammation.	19924457
Inflammation	Altered Intercellular Communication	Studies designed to investigate OSA-associated inflammation should carefully match the control group subjects.	19924457
Carcinogenesis, Malignant neoplasm of endometrium	Altered Intercellular Communication	In conclusion, our findings confirmed a reduction in risk of endometrial cancer with factors associated with a lower cumulative exposure to estrogen and/or higher exposure to progesterone, such as increasing number of FTPs and shorter menstrual lifespan and, therefore, support an important role of hormonal mechanisms in endometrial carcinogenesis.	19924816
Inflammation, Lymphoid	Altered Intercellular Communication	Nevertheless, infection of lymphoid cells, sustained by a low level of replication, could be sufficient to increase the local injury through an autologous mechanism of inflammation.	19926147
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	We evaluated the influence of inflammation on cardiac endocrine function in autoimmune rheumatic disease (RD) patients with preserved left ventricular systolic function.	19926149
Inflammation, atherosclerotic	Altered Intercellular Communication	Four atherosclerotic stages were defined by signs of degeneration and inflammation in sections stained with Elastica-van-Gieson and immunohistology, respectively.	19926495
Inflammation, Atherosclerosis	Altered Intercellular Communication	Less severe atherosclerosis in the IMA than in the SMA was associated with stronger signs of inflammation.	19926495
Sleep-Disordered Breathing, No metabolic abnormalities, daytime sleepiness, Inflammation	Altered Intercellular Communication	Sleep-disordered breathing in obese children is associated with prevalent excessive daytime sleepiness, inflammation, and metabolic abnormalities.	19926716
vascular inflammations, Dental Plaque	Altered Intercellular Communication	Our data suggest that neurotransmitters such as substance P are capable of promoting mast cell dependent plaque destabilization and provide a new, direct link between neural factors and vascular inflammation.	19926877
vascular inflammations, Dental Plaque	Altered Intercellular Communication	Our data suggest that neurotransmitters such as substance P are capable of promoting mast cell dependent plaque destabilization and provide a new, direct link between neural factors and vascular inflammation.	19926877
Inflammation	Altered Intercellular Communication	Patients from group III had more prominent inflammation, but only 35% of them were H. pylori (+).	19927999
Inflammation	Altered Intercellular Communication	Cellular proliferation had positive correlation with inflammation grade in groups II and III (P <0,05).	19927999
Primary hypogonadism	Altered Intercellular Communication	The hormonal tests were performed that allowed to diagnose the hypergonadotropic hypogonadism.	19928664
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Both multifocal fibrosclerosis and hypertrophic pachymeningitis are rare disorders of unknown etiology, characterised by chronic inflammation leading to dense fibrosis.	19928692
Inflammation, Hemorrhage, Azotemia, Graft-vs-Host Disease	Altered Intercellular Communication	Instead, bleeding risk was determined by platelet count, presence of inflammation, azotemia, presence of graft-versus-host disease and treatment with low-molecular weight heparin.	19929239
Inflammation	Altered Intercellular Communication	The increase in visfatin may contribute to low-grade systemic inflammation associated with MetS.	19929281
Orbital Pseudotumor	Altered Intercellular Communication	Triamcinolone acetonide injection for persistent atypical idiopathic orbital inflammation.	19929669
Orbital Pseudotumor	Altered Intercellular Communication	To report a patient with atypical idiopathic orbital inflammation who was successfully treated with intra-orbital injections of triamcinolone acetonide.	19929669
Conjunctivitis, Orbital Pseudotumor, Right eye	Altered Intercellular Communication	A 71-year-old female with right orbital mass and conjunctival inflammation underwent orbital biopsy that was consistent with the diagnosis of atypical idiopathic orbital inflammation.	19929669
Orbital Pseudotumor	Altered Intercellular Communication	Intra-orbital injections of triamcinolone acetonide may be an effective alternative in patients with atypical idiopathic orbital inflammation unresponsive to systemic steroids.	19929669
Inflammation, "Cyst of Skenes duct", Congenital Abnormality	Altered Intercellular Communication	In the adult female, a cyst of the Skene's duct is a rare event that may be either the late consequence of a congenital abnormality or the result of a chronic acquired inflammation.	19929913
Inflammation	Altered Intercellular Communication	Patients with NAEC were characterized by mild eosinophilic inflammation and only minor structural conjunctival changes.	19930216
Inflammation, Carcinogenesis	Altered Intercellular Communication	The transcription factor Nuclear factor kappa B (NF-kappaB) is central to the regulation of genes encoding for mediators of inflammation and carcinogenesis.	19930402
Barrett Esophagus, Inflammation, Adenocarcinoma	Altered Intercellular Communication	In the esophagus, NF-kappaB is progressively activated from inflammation to Barrett's metaplasia and adenocarcinoma.	19930402
Inflammation	Altered Intercellular Communication	The diagnoses of GU in 21(66%), DU in 16(50%), GC in 20(50%) and NUD in 50(42%) were associated with moderately active chronic inflammation.	19930551
Inflammation	Altered Intercellular Communication	CagA in 55(45%) (p = 0.037), vacA s1am1 in 51(51%) (P < 0.001), s1bm1 in 25(56%) (p = 0.002), s1am2 32(30%) (p < 0.001) and s1bm2 29(69%) (p = 0.004) were also associated with moderately active chronic inflammation.	19930551
Inflammation, Disease	Altered Intercellular Communication	VacA allele's s1am1 and s1bm1 were associated with H. pylori associated diseases and inflammation.	19930551
Inflammation	Altered Intercellular Communication	Chronic low-grade inflammation is a characteristic of ageing that may lead to alterations in health status and quality of life.	19930773
Airway structure, Granulomatosis with polyangiitis, Subglottic stenosis, Disease remission	Altered Intercellular Communication	In patients with Wegener's granulomatosis, subglottic stenosis can develop due to active disease; however, some patients develop subglottic stenosis with no clear evidence of airway inflammation.	19930784
Inflammation, Sleep Apnea, Obstructive, Blood coagulation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	This study indicates that OSAS is associated with inflammation and increased IVST in ACS patients after successful PCI and, in elderly ACS patients, also with CAD severity and enhanced blood coagulability.	19930839
Inflammation	Altered Intercellular Communication	Plaque instability might be caused, however, by pathophysiologic processes, such as inflammation ("panarteritis"), that exert adverse effects throughout the coronary vasculature and therefore result in multiple unstable lesions and multivessel thromboses.	19931792
Inflammation, Intervertebral Disc Degeneration, Pain Distress Question	Altered Intercellular Communication	Once degenerative disc disease has begun, the tissue inflammation that accompanies DDD may further increase vitamin C requirements in the affected patient, thereby creating a cascade of positive feedbacks that potentially accelerates and contributes to further disc degeneration and low-back pain.	19932568
methyldopa, Inflammation, Cataract	Altered Intercellular Communication	These data suggest only a weak link between systemic inflammation and AMD and cataract in Asian people.	19933187
Inflammation, Degenerative disorder	Altered Intercellular Communication	Early-stage findings consisted of inflammatory changes involving adjacent vertebral endplates and mimicking degenerative disk disease with inflammation.	19933625
Inflammation, Synovitis	Altered Intercellular Communication	A synovitis grading system was used to determine the severity of synovial inflammation.	19933745
Inflammation, Morbidity - disease rate	Altered Intercellular Communication	This chronic inflammation, or ''inflammaging'' as it has been termed, seems to be associated with a host of adverse effects contributing to many of the health problems that increase morbidity and decrease both quality of life and the ability to maintain independence in old age.	19934111
Inflammation, Chronic disease, Atherosclerosis	Altered Intercellular Communication	At the same time, inflammation arising from atherosclerosis and other chronic diseases further contributes to the inflammatory milieu and effects a state of chronic inflammation.	19934111
Inflammation, Morbidity - disease rate	Altered Intercellular Communication	This chronic inflammation, or ''inflammaging'' as it has been termed, seems to be associated with a host of adverse effects contributing to many of the health problems that increase morbidity and decrease both quality of life and the ability to maintain independence in old age.	19934111
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	Subsequent biopsies showed granulomatous inflammation consistent with sarcoidosis.	19934463
Retinal Perforations, Intraocular inflammation, Endophthalmitis, CTCAE, Retinal Detachment	Altered Intercellular Communication	The charts were reviewed to identify the complications of endophthalmitis, intraocular inflammation, retinal tear, and retinal detachment.	19934815
Endophthalmitis, CTCAE, Uveitis	Altered Intercellular Communication	Two cases of unilateral culture-proven endophthalmitis occurred after bilateral intravitreal ranibizumab, and one case of unilateral acute intraocular inflammation occurred after bilateral intravitreal bevacizumab.	19934815
Endophthalmitis, CTCAE, Uveitis	Altered Intercellular Communication	The incidence of culture-proven endophthalmitis was 0.065%, and the incidence of acute intraocular inflammation was 0.033%.	19934815
Uveitis	Altered Intercellular Communication	Severe acute intraocular inflammation can occur unilaterally after same-day bilateral injections of bevacizumab.	19934815
Inflammation, Metabolic Syndrome X, Coronary heart disease	Altered Intercellular Communication	The influence of cardiac rehabilitation on inflammation and metabolic syndrome in women with coronary heart disease.	19935427
Inflammation, Hepatitis C	Altered Intercellular Communication	These findings raise the possibility that in some cases hepatitis C infection and inflammation can be directly oncogeneic.	19935643
Inflammation, Esophagitis	Altered Intercellular Communication	Esophageal dilation in eosinophilic esophagitis: effectiveness, safety, and impact on the underlying inflammation.	19935783
Esophagitis	Altered Intercellular Communication	In addition, we examined the influence of dilation on the underlying esophageal inflammation.	19935783
Inflammation	Altered Intercellular Communication	Symptom improvement despite persistence of inflammation suggests that tissue remodeling contributes substantially to symptom generation in EoE.	19935783
Dystrophy, Inflammation, Cerebral Amyloid Angiopathy	Altered Intercellular Communication	They develop robust AD-like cerebral beta-amyloid plaque pathology with glial inflammation, signs of neuritic dystrophy and cerebral amyloid angiopathy.	19936202
Inflammation, Idiopathic Pulmonary Fibrosis, Liver diseases, Autoimmune Diseases, Fibrosis Assessment, Macrocytosis, Leukemia, Myelocytic, Acute	Altered Intercellular Communication	In six generations of a large family, a loss-of-function mutation in the telomerase enzyme gene TERT associated with severe telomere shortening and a range of hematologic manifestations, from macrocytosis to acute myeloid leukemia, with severe liver diseases marked by fibrosis and inflammation, and one case of idiopathic pulmonary fibrosis but not with autoimmune disorders.	19936245
Inflammation, Fibrosis Assessment, Epithelial	Altered Intercellular Communication	Our analyses showed that 60% of HCV positive samples showed nasal epithelial erosion, 95% showed subepithelial non-specific inflammation and/or fibrosis, while only 5% showed normal histology.	19936373
Prostate carcinoma, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	To study the association and possible relationship of prostate inflammation with benign prostatic hyperplasia (BPH), and prostate cancer.	19936421
Inflammation, Acute inflammation	Altered Intercellular Communication	Of them, only one demonstrated acute inflammation, while 87/88 demonstrated chronic inflammation with, or without acute inflammation.	19936421
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Histopathologic features were categorized into 3 main categories: inflammation alone (12/214, 5.6%), BPH category (126/214, 58.9%), and cancer category (76/214, 35.5%) patients.	19936421
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	In the overall analysis of 214 specimens, BPH with inflammation was more prevalent than cancer with inflammation (43/214 [20.1%] versus 33/214 [15.4%]).	19936421
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	In a subgroup analysis within each category, inflammation was less prevalent in the BPH category compared to the cancer category (43/126 [34.1%] versus 33/76 [43.4%]).	19936421
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The association between chronic inflammation and both BPH and cancer is obvious in our study.	19936421
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Further studies are needed to substantiate this observation, and to clarify the magnitude of association of inflammation with BPH compared to cancer.	19936421
vascular inflammations, Metabolic Syndrome X	Altered Intercellular Communication	Evaluation of the degree of vascular inflammation in patients with metabolic syndrome.	19936455
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Inflammation in IBD may be caused by the loss of homeostasis between CD4+ CD25high Foxp3+ regulatory cells (Treg) and proinflammatory Th17 cells.	19936899
PMF Regimen, Granulomatous inflammation, Carcinoma of lung	Altered Intercellular Communication	Therefore, it might have a limited role in the diagnosis of PMF with possible concurrent granulomatous inflammation or lung cancer.	19937406
Inflammation, Ulcer	Altered Intercellular Communication	Colonoscopy was normal in 11 (45.8%), showed inflammation or superficial ulcers in 7 (29.1%) and solitary or multiple deep ulcers in 6 (25%).	19937416
Neurogenic Inflammation, Data types - Address, physiopathological	Altered Intercellular Communication	Of the 5485 genes found to be significantly altered in AD, there were consistent patterns of changes which show that the AD transcriptome in neocortex is characterized by changes indicative of synaptic dysfunction, perturbed neurotransmission and activation of neuroinflammation.	19937809
Inflammation, N-nitrosomorpholine, Neuromyelitis Optica	Altered Intercellular Communication	Severe inflammation and astrocyte loss with profound demyelination in spinal cord and optic nerves are typical pathological features of neuromyelitis optica (NMO).	19937948
Inflammation, N-nitrosomorpholine	Altered Intercellular Communication	Human anti-AQP-4 antibodies are not only important in the diagnosis of NMO but also augment disease and induce NMO-like lesions in animals with T-cell-mediated brain inflammation.	19937948
Hormone abnormality	Altered Intercellular Communication	Many conditions including hormonal abnormality are associated with this syndrome.	19938750
Hyponatremia	Altered Intercellular Communication	Hormonal changes will cause fluctuation in hyponatremia and correction of hyponatremia, even if the recommended rate may be hazardous and will promote ODS.	19938750
Inflammation	Altered Intercellular Communication	Microscopic examination of the biopsy specimens suggested only chronic inflammation.	19938751
Retinal Pigments, Inflammatory abnormality of the eye	Altered Intercellular Communication	There was no evidence of ocular inflammation or related retinal or retinal pigment epithelial changes.	19939456
Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Degenerative polyarthritis, Obesity, No metabolic abnormalities	Altered Intercellular Communication	Osteoarthritis (OA) and cardiovascular disease (CVD) share age and obesity as risk factors, but may also be linked by pathogenic mechanisms involving metabolic abnormalities and systemic inflammation.	19940413
Chronic inflammation, Neoplasms	Altered Intercellular Communication	At virtual and conventional cystoscopies, the conditions of 3 patients, 2 with chronic inflammations and 1 with foreign body reaction, were wrongly diagnosed as tumors.	19940652
Inflammation, Fever, CTCAE, Mumps, Deafness, Virus Diseases, Orchitis	Altered Intercellular Communication	Mumps is a vaccine-preventable viral infection characterized by fever and inflammation of the salivary glands and whose complications include orchitis, deafness, and meningo-encephalitis.	19940833
Inflammation, Obesity	Altered Intercellular Communication	However, obesity is associated with disability and with physiological markers also recently linked with frailty, for example, increased inflammation and low antioxidant capacity.	19942592
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Although inflammation has been shown to be implicated in the pathophysiology of atrial fibrillation (AF), little is known about its involvement in the accompanying atrial electrical remodeling expressed by P wave dispersion (P(disp)).	19942863
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	In hypertensive subjects hs-CRP and P(disp) are interrelated and associated with AF, suggesting an active implication of inflammation in the atrial electrophysiological remodeling predisposing to AF.	19942863
Infertility	Altered Intercellular Communication	Studies of the anatomy and the physiology of the uterine-tubal junction (UTJ), with a main concern for the muscular pattern and the secretory activity of this part of the tube, in relation with the hormonal and nervous control, can play an important role in understanding and impairment of infertility.	19942965
Perforation (observation)	Altered Intercellular Communication	The histopathologic report revealed granulomatous giant-cellular inflammation in the margins of the perforation.	19942978
Inflammation, Perforation of ileum	Altered Intercellular Communication	The granulomatous giant-cellular inflammation of foreign body is a rare cause of ileal perforation.	19942978
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	The cytokine hypothesis suggests that there is an association between chronic heart failure (CHF) and inflammation.	19944358
Inflammation	Altered Intercellular Communication	In a subgroup of 15 subjects, reduced post-exercise HRR was associated with increased serum markers of inflammation (interleukin-6, r = 0.58, P = .024; high-sensitivity C-reactive protein, r = 0.66, P = .007).	19944361
Inflammation	Altered Intercellular Communication	Pathophysiologic links between autonomic function and inflammation may be mediators of this association.	19944361
Inflammation, "Alzheimers Disease", Postoperative cognitive dysfunction	Altered Intercellular Communication	Inflammation: a bridge between postoperative cognitive dysfunction and Alzheimer's disease.	19944539
Refractory anemias, Inflammation	Altered Intercellular Communication	Simultaneously, RA activity was assessed using inflammation markers, MMP-3 and the Disease Activity Score in 28 joints (DAS-28) based on CRP [DAS-28(CRP)] and ESR[DAS-28(ESR)].	19944558
daytime sleepiness	Altered Intercellular Communication	Increased daytime sleepiness in this middle aged series was related to female (hormonal status and sedentarism) and partner factors; several which are susceptible of intervention.	19945237
vascular inflammations	Altered Intercellular Communication	PTX3 may be a useful marker for localized vascular inflammation and damage to the cardiovascular system.	19945702
Inflammation, Dyslipidemias, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	Obesity, dyslipidemia, and inflammation were prominent among HIV-infected adolescent women and, coupled with other risk factors, may accelerate the lifetime risk of cardiovascular disease and other adverse events.	19947855
Airway structure	Altered Intercellular Communication	Analysis of exhaled breath condensate (EBC) pH is a non-invasive method to study airway inflammation.	19947991
Lymphocyte count increased, Inflammation	Altered Intercellular Communication	Increased C-reactive protein with lymphocytosis suggested inflammation as its cause.	19950763
Bronchitis	Altered Intercellular Communication	Orally administered inactivated nontypeable Haemophilus influenzae (NTHi) can drive a specific T-cell response that by promoting intrabronchial phagocytosis down-regulates bronchus inflammation.	19952063
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	Relationship between renal resistive index and inflammation in untreated hypertensive patients.	19952472
Inflammation, Hypertensive (finding), Albuminuria	Altered Intercellular Communication	Renal resistive index is associated with inflammation and may be a useful marker, together with albuminuria, in hypertensive patients when evaluating hypertensive renal damage.	19952472
Inflammation, Parakeratosis, Acantholysis, Hyperkeratosis	Altered Intercellular Communication	For each case, the following histologic features were evaluated and their association with disease course was examined: pseudo-invasion, adnexal involvement, signet-ring cells, cytologic atypia, glands formation, epidermal acantholysis, parakeratosis, hyperkeratosis, and chronic inflammation.	19952933
Inflammatory abnormality of the eye	Altered Intercellular Communication	Of the 19 eyes, 14 showed moderate to severe ocular inflammation immediately after injection.	19952993
Inflammation, Vitreous opacities	Altered Intercellular Communication	Five eyes with severe inflammation underwent pars plana vitrectomy because of dense vitreous opacity.	19952993
ovarian neoplasm	Altered Intercellular Communication	Physical activity may influence ovarian cancer risk through hormonal, inflammatory, or immune-mediated processes or by suppressing ovulation.	19953315
Nasal inflammation	Altered Intercellular Communication	Even numbered 3-OHFA were most strongly associated with nasal inflammation.	19953416
Airway structure	Altered Intercellular Communication	This is the first study to evaluate the relationship between endotoxin's 3-OHFA constituents in agricultural dust and nasal airway inflammation.	19953416
Inflammation, Fatty degeneration	Altered Intercellular Communication	Steatosis was infrequent and focal or even absent, whereas variable grades of Mallory hyaline and inflammation were consistently present.	19954815
Inflammatory Bowel Diseases	Altered Intercellular Communication	TRAIL was downregulated in enterocytes of patients with IBD, but was upregulated in mononuclear cells in areas of active mucosal inflammation.	19954896
Inflammatory disease of mucous membrane	Altered Intercellular Communication	TRAIL-R2 and TRAIL-R4 were strongly downregulated in the surface epithelium in any kind of mucosal inflammation.	19954896
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	We hypothesized that systemic inflammation in patients with chronic obstructive pulmonary disease (COPD) may influence Epo production, particularly during episodes of exacerbation of the disease (ECOPD) where an inflammatory burst is known to occur.	19955699
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	These results show that the plasma levels of Epo are reduced during ECOPD likely in relation to a burst of systemic inflammation.	19955699
Inflammation, Observation Method - Coagulation, Endothelial dysfunction	Altered Intercellular Communication	Morning fasting blood samples were collected to determine measures of inflammation, coagulation and endothelial dysfunction.	19955705
Inflammation, Impaired health, Endothelial dysfunction	Altered Intercellular Communication	Perceived impairment in sleep related to increased coagulation activity and endothelial dysfunction in all participants, whereas objectively impaired sleep related to inflammation activity in caregivers.	19955705
Inflammation	Altered Intercellular Communication	Exercise training as a treatment for chronic inflammation in the elderly.	19955865
Disability, Inflammation, Chronic disease, Sarcopenia	Altered Intercellular Communication	Persistent subclinical inflammation predisposes to chronic disease, as well as the development of sarcopenia and disability, in frail elderly.	19955865
Inflammation	Altered Intercellular Communication	This article highlights emerging data suggesting that increasing physical activity could be effective for reducing chronic inflammation in the elderly.	19955865
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	Traditionally, heparanase activity was implicated in cellular invasion associated with angiogenesis, inflammation, and cancer metastasis.	19955948
Coronary Occlusion, Neoplasms	Altered Intercellular Communication	Urgent coronary angiography excluded an acute coronary occlusion, whereas high-resolution computed tomography of the chest revealed tumor infiltration and associated acute inflammation of the pericardial sac.	19956075
Autoimmune Diseases	Altered Intercellular Communication	Predominance of women in autoimmune diseases suggests that sex hormones may play a role in disease susceptibility.	19957009
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation is a key component of Alzheimer's disease (AD), and we have examined the effect of two polymorphisms (-174G/C and -572C/G) in the promoter of the inflammatory cytokine interleukin-6 (IL-6) gene on risk of AD in 318 AD patients.	19957198
Inflammation, Hyperemia	Altered Intercellular Communication	In such cases PV was macroscopically not changed or had various grades of change--from hyperemia, cicatricial thickening and involvement into adhesive process to its pronounced inflammation and destruction.	19957726
Inflammation, Pleurisy	Altered Intercellular Communication	The reported complications after video-assisted thoracoscopical operations--4 purulent inflammation of thoracoportal incisions, 3--marginal pleuritis.	19957756
Inflammation, Primary, Ulcerative Colitis	Altered Intercellular Communication	If apoptosis is a primary defect, apoptosis rates could influence the degree of spreading of inflammation and the clinical course of UC.	19958058
Inflammation	Altered Intercellular Communication	However, increased microscopic inflammation inversely correlated with apoptosis response to the Fas ligand (p< 0.06).	19958058
Airway structure, IL13 gene	Altered Intercellular Communication	Allergic rhinitis (AR) is characterized in part by hyperresponsiveness to nonspecific stimuli, a phenomenon that reflects the fundamental role of nasal neural pathways in chronic airway inflammation.	19958603
Inflammation	Altered Intercellular Communication	Alterations in neurogenic inflammation may contribute to the pathophysiology of CRS and provide alternative therapeutic targets.	19958603
Cessation of life, Necrosis with inflammation	Altered Intercellular Communication	Previous studies have shown that declines in human fibroblast ATP levels interfere with programmed cell death and promote necrotic inflammation.	19958786
Inflammation	Altered Intercellular Communication	We discuss the differential diagnoses and various diagnostic tests with respect to granulomatous inflammation of the meninges.	19960146
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Pulmonary fibrosis represents the final evolution of a chronic inflammation and is defined by the overgrowth of fibroblasts and exaggerated extracellular matrix deposition.	19960789
Inflammation, Granulomatous inflammation, Granuloma	Altered Intercellular Communication	Colonoscopic biopsy specimens showed nonspecific inflammation in 1 case; however, they showed only granulomatous inflammation in a second case and granulomas associated with fungal hyphae in a third.	19961248
Inflammation, Congestive heart failure	Altered Intercellular Communication	Congestive heart failure (CHF) has been associated with elevated biomarker levels reflecting chronic low-grade inflammation.	19961288
Inflammation, Simultaneous, Congestive heart failure	Altered Intercellular Communication	Most likely, elevated YKL-40 levels in CHF patients are explained by the presence of concomitant diseases but a role of YKL-40 in low-grade inflammation is not excluded.	19961288
Inflammation	Altered Intercellular Communication	Cases with an irregularly thickened and/or calcified cyst wall, presumably due to chronic inflammation of the wall, are rare.	19961317
Inflammation, Coronary heart disease, atherosclerotic, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	To investigate the association between hemoglobin scavenger receptor (CD163) expression levels on monocytic surfaces and coronary atherosclerotic severity in patients with coronary heart disease (CHD) as well as the roles of CD163 in inflammation and lipidperoxidation.	19961729
Inflammation, Neoplasms	Altered Intercellular Communication	Current evidence suggests that chronic inflammation is associated with tumor development and progression.	19961892
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Interleukin-18 (IL-18) plays a central role in inflammation and the immune response, contributing to the pathogenesis and pathophysiology of infectious and inflammatory diseases.	19961892
Inflammation, Neoplasms, Communicable Diseases, Aneurysm, Traumatic injury	Altered Intercellular Communication	We excluded infection, inflammation, trauma, and neoplasia as causes of the aneurysm.	19962251
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Low inflammation and low fibrosis in AAH was associated with the increase of codon 10CC (high producer) and codon 25CC (low producer) genotypes.	19962351
Aneurysm, Inflammation, Fever, CTCAE	Altered Intercellular Communication	In conclusion, CA dilation only and CA aneurysms differ only in the total duration of inflammation, as measured by the number of days from fever onset to defervescence.	19962487
Inflammation, Heart failure	Altered Intercellular Communication	Studies indicate that myeloperoxidase (MPO) is associated with disease progression and severity in heart failure (HF), while it may provide a mechanistic link between inflammation and adverse cardiac remodeling.	19962701
Inflammation, Thrombosis	Altered Intercellular Communication	It has recently been established that platelets have an important role in increasing inflammation, in addition to their main role in hemostasis and thrombosis.	19962788
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	The nuclear enzyme poly(ADP-ribose) polymerse-1 (PARP-1) has previously been reported to play an important role in lipopolysaccharide (LPS)-induced pulmonary inflammation and is highly activated in COPD patients.	19962977
Presenile dementia, Inflammation	Altered Intercellular Communication	Hemostasis and inflammation have been implicated in dementia.	19965782
Inflammation, VAD I protocol, ETV3 wt Allele	Altered Intercellular Communication	Moreover, those with MetS and high inflammation had a still further higher risk of VaD (multivariate adjusted HR, 9.55; 95% CI 1.17 to 78.17) compared with those without MetS and high inflammation.	19965842
Inflammation, VAD I protocol, ETV3 wt Allele	Altered Intercellular Communication	On the other hand, those with MetS and low inflammation compared with those without MetS and low inflammation did not exhibit a significant increased risk of VaD (adjusted HR, 3.31, 95% CI 0.91 to 12.14).	19965842
Inflammation, VAD I protocol, ETV3 wt Allele	Altered Intercellular Communication	In our population, MetS subjects had an elevated risk of VaD that increased after excluding patients with baseline undernutrition and selecting MetS subjects with high inflammation.	19965842
Inflammation, Hyperplasia	Altered Intercellular Communication	Preprocedural inflammation does not affect neointimal hyperplasia following everolimus-eluting stent implantation.	19966361
Inflammation, Hyperplasia	Altered Intercellular Communication	Our results suggest that preprocedural inflammation does not affect neointimal hyperplasia following EES implantation.	19966361
Dacryoadenitis	Altered Intercellular Communication	The murine lacrimal gland expresses high levels of macrophage MIF without any evidence of lacrimal gland inflammation.	19966563
Necrotizing granulomatous inflammation, Acne, Lupus Erythematosus	Altered Intercellular Communication	Acne agminata (lupus miliaris disseminatus faciei, acnitis, papular tuberculid) is a rare form of necrotizing granulomatous inflammation of the dermis that has received scant attention in the ophthalmologic literature.	19966664
Inflammation	Altered Intercellular Communication	Inflammation is a complex and necessary component of an organism's response to biological, chemical or physical stimuli.	19967506
Tissue damage, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Persistent inflammation as a result of prolonged exposure to stimulus or an inappropriate reaction to self molecules can lead to the chronic phase, in which tissue damage and fibrosis can occur.	19967506
Inflammation, Primary malignant neoplasm, Allergy - Charge Type Reason, Autoimmune Diseases, Atherosclerosis, Diabetes Mellitus, Arthritis, Asthma	Altered Intercellular Communication	Chronic inflammation is reported to contribute to numerous diseases including allergy, arthritis, asthma, atherosclerosis, autoimmune diseases, diabetes, and cancer, and to conditions of aging.	19967506
Chronicity	Altered Intercellular Communication	The specific profile in a given inflammatory condition is dependent upon species, mechanisms, severity, chronicity, and capacity of the immune system to respond and adapt.	19967506
Inflammation, Osteoporosis, Penile Diseases	Altered Intercellular Communication	Osteoporosis as a chronic senile disease is associated with inflammation, and the role of inflammatory mediators has been demonstrated in recent years.	19967563
selenium	Altered Intercellular Communication	CCD in SE may represent injury caused by excessive neuronal transmission from prolonged excitatory synaptic activity via the cortico-pontine-cerebellar pathway.	19967565
Inflammation	Altered Intercellular Communication	Growing evidence supports a role for inflammation in its pathogenesis but no potential target for intervention has emerged.	19967568
Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation modifies the association of osteoprotegerin with mortality in chronic kidney disease.	19967657
Inflammation, Endothelial dysfunction, Chronic Kidney Diseases	Altered Intercellular Communication	As clinical and experimental studies have implicated OPG in atherogenesis, we investigated serum OPG in relation to inflammation, endothelial dysfunction and oxidative stress markers in 265 chronic kidney disease (CKD) stage 5 patients.	19967657
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Cardiovascular disease (CVD), carotid plaques (n=69) and mortality (5 years) in relation to OPG were also analyzed, and the impact of inflammation on the association of OPG with mortality was evaluated.	19967657
Inflammation, Endothelial dysfunction, Chronic Kidney Diseases	Altered Intercellular Communication	Elevated OPG levels are associated with surrogate markers of inflammation, endothelial dysfunction, oxidative stress and CVD in CKD patients.	19967657
Inflammatory abnormality of the eye	Altered Intercellular Communication	Two hundred fifteen patients with noninfectious ocular inflammation observed from initiation of cyclophosphamide.	19969366
Inflammatory abnormality of the eye, Uveitis, Scleritis	Altered Intercellular Communication	The 215 patients (381 involved eyes) meeting eligibility criteria carried diagnoses of uveitis (20.4%), scleritis (22.3%), ocular mucous membrane pemphigoid (45.6%), or other forms of ocular inflammation (11.6%).	19969366
Meningioma, Inflammation, Brain Neoplasms	Altered Intercellular Communication	The majority of these findings were owing to inflammation (12 of 15); a case of low grade lymphoma was detected; two patients showed focal brain uptake of 18F-choline and were subsequently submitted to magnetic resonance: in one a meningioma and in the other a low-grade brain tumour were diagnosed.	19972635
Communicable Diseases, Inflammation, Pain Distress Question	Altered Intercellular Communication	There was a significant reduction in pain scores on days 1 and 2 in the patients treated with an absorbable continuous subcuticular suture, and no difference in inflammation or infection.	19995253
Inflammation, Pseudotumor, Necrosis	Altered Intercellular Communication	Necrosis and inflammation in peri-implant soft tissues have been described in failed second-generation metal-on-metal (MoM) resurfacing hip arthroplasties and in the pseudotumors associated with these implants.	19995315
Inflammation	Altered Intercellular Communication	Similar results were found for C-reactive protein, a related marker of chronic inflammation.	19995479
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Adverse childhood experiences and adult risk factors for age-related disease: depression, inflammation, and clustering of metabolic risk markers.	19996051
Airway structure, Asthma	Altered Intercellular Communication	RATIONALE Airway inflammation in asthma is heterogeneous with different phenotypes.	19996343
Inflammation, Malnutrition, Helminthiasis, Anemia, Malaria	Altered Intercellular Communication	Early helminth infections are inversely related to anemia, malnutrition, and malaria and are not associated with inflammation in 6- to 23-month-old Zanzibari children.	19996438
Inflammation, Helminths	Altered Intercellular Communication	Although helminths were not associated with inflammation, their association with Hb or MUAC-for-age Z score was modified by inflammation.	19996438
Intestinal metaplasia, Inflammation, Gland	Altered Intercellular Communication	An experienced pathologist assessed the biopsies for the presence and grade of inflammation, activity, glandular atrophy, intestinal metaplasia, presence and density of H. pylori and presence of lymphoid follicles or aggregates.	19996618
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Evidence is accumulating indicating that chronic inflammation plays an important role in prostate cancer.	19996656
Vitritis, Inflammation, Panuveitis	Altered Intercellular Communication	Two other patients, after one injection only, had evidence of inflammation (vitritis or panuveitis) on examination at Week 6.	19996827
Communicable Diseases, Inflammation	Altered Intercellular Communication	Optimal structural outcome was defined as resolution of inflammation and infection.	19996830
Inflammation, Retractile Mesenteritis	Altered Intercellular Communication	Sclerosing mesenteritis (SM) is an uncommon disorder characterized by chronic nonspecific inflammation involving the adipose tissue of the mesentery.	19996846
Foveolar hyperplasia, Gastritis, Hypertrophic	Altered Intercellular Communication	Biopsies of the stomach showed marked foveolar hyperplasia with active inflammation and gland changes consistent with Menetrier disease.	19996862
Inflammation, Intracranial Aneurysm	Altered Intercellular Communication	Inflammation and activation of the complement system in the intracranial aneurysm (IA) wall predispose to IA rupture.	19997064
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Environmental exposures filtered through the genetic make-up of each individual alter the transcriptional repertoire in organs central to metabolic homeostasis, thereby affecting arterial lipid accumulation, inflammation, and the development of coronary artery disease (CAD).	19997623
Retinal Diseases	Altered Intercellular Communication	Inflammation affects the formation and the progression of various vitreoretinal diseases.	19997642
Inflammation, Retinal Diseases	Altered Intercellular Communication	Major three factors: IL-6, IL-8, and MCP-1 were strongly correlated with each other indicating a common pathway involved in inflammation process in vitreoretinal diseases.	19997642
Hyperlipidemia, Inflammation	Altered Intercellular Communication	Our results indicate that improvement of insulin resistance, lipidemia, and blood pressure as well as reduction of systemic inflammation after bariatric surgery were associated with the increase of serum NO concentration.	19997784
Hematoxylin and eosin stain method, Inflammation	Altered Intercellular Communication	H&E and immunohistochemical stained slides were reviewed for the presence of inflammation, ganglion cells, and interstitial cells of Cajal (ICCs).	19997975
Gastroparesis, Congenital neurologic anomalies, Inflammation	Altered Intercellular Communication	Thus, histologic abnormalities in gastroparesis are heterogeneous and include myenteric inflammation, decreased innervation, and reduction of ICCs.	19997975
Pain Distress Question, Inflammation	Altered Intercellular Communication	The study confirms that the target medication provides a safe and rapid pain reduction and improvement of inflammation in very young children suffering from painful acute inflammatory ear conditions.	19998578
Histiocytosis, Langerhans-Cell	Altered Intercellular Communication	[A case of Langerhans cell histiocytosis coincident with severe external ear canal inflammation].	19999153
Histiocytosis, Langerhans-Cell, Inflammation	Altered Intercellular Communication	We report a case of Langerhans cell histiocytosis (LCH), a rare disease caused by the proliferation of abnormal Langerhans cells, coincident with severe external ear canal inflammation.	19999153
Histiocytosis, Langerhans-Cell, Inflammation, Temporal bone structure	Altered Intercellular Communication	LCH should therefore be considered in the case of a patient with severe external ear canal inflammation coincident with temporal bone erosion.	19999153
Adenocarcinoma, Inflammation, Tuberculosis, Granulomatous inflammation	Altered Intercellular Communication	Eighteen cases (40%) showed non specific chronic inflammation, 10 (22.2%) cases showed caseating granulomatous inflammation suggestive of tuberculosis and 6 (13.3%) cases showed metastatic adenocarcinoma.	19999215
Inflammation, Low Vision, diabetic, Uveitis	Altered Intercellular Communication	Diabetic patients presenting with uveitis, whatever the aetiology, may have severe inflammation, reduced vision, and poor glycaemic control.	20001257
Intraocular inflammation, Mucopolysaccharidosis I	Altered Intercellular Communication	MPS was able to control intraocular inflammation without relapse in 30 patients (85.7%).	20001262
Inflammation	Altered Intercellular Communication	Its synthesis is up-regulated in chronic inflammation and iron excess.	20002304
Hepatitis	Altered Intercellular Communication	Our results suggest that HBV infection and liver inflammation are independently associated with ICC development.	20002305
Inflammation, Asthma, Atopy	Altered Intercellular Communication	Markers of eosinophilic and neutrophilic inflammation in bronchoalveolar lavage of asthmatic and atopic children.	20002661
Inflammation, Asthma, MS4A2 wt Allele	Altered Intercellular Communication	Eosinophilic, but also neutrophilic, inflammation has been described in asthma, but the relationship with atopy was incompletely investigated.	20002661
Inflammation, Asthma	Altered Intercellular Communication	This pattern of inflammation was observed in both preschool and school-aged asthmatic children.	20002661
Inflammation, Asthma, Atopy	Altered Intercellular Communication	This study suggests that markers of eosinophilic, but not neutrophilic inflammation, are increased in asthmatic children and also in atopic children without asthma.	20002661
Inflammation, Epithelial metaplasia	Altered Intercellular Communication	Epithelial metaplasia is a phenomenon where a native mucosal cell type is replaced by another due to altered stem cell differentiation, usually as the result of long-standing injury or inflammation.	20003139
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The role of 25-hydroxyvitamin D deficiency in promoting insulin resistance and inflammation in patients with chronic kidney disease: a randomised controlled trial.	20003316
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The current study indicates an independent relationship between high-fat as well as low-fat dairy consumption, not total dairy intake, and some markers of inflammation and endothelial dysfunction.	20003635
Inflammation, Liver carcinoma, Hepatitis B, Malignant Neoplasms, FAM126A gene	Altered Intercellular Communication	Hepatocellular carcinoma (HCC) is a frequent malignancy with a high rate of mortality, and the hepatitis B and C viruses are considered major etiological factors associated with the development of chronic inflammation.	20003764
Meckel Diverticulum, Orchitis, Perforation (observation), Intraabdominal hemorrhage	Altered Intercellular Communication	[Perforation of Meckel's diverticulum with intraabdominal hemorrhage and periappendicular inflammation].	20003860
Inflammation	Altered Intercellular Communication	Haemoperitoneum, perforated MD and peri-appendicular inflammation were found during laparotomy.	20003860
Airway structure, Sleep Apnea, CTCAE, Obesity	Altered Intercellular Communication	Systemic and airway inflammation in sleep apnea and obesity: the role of ICAM-1 and IL-8.	20004360
Airway structure, Osage language	Altered Intercellular Communication	The data obtained confirm the occurrence of an ICAM- and IL-8-mediated neutrophilic airway inflammation in both OSA and obese patients.	20004360
Inflammation, Comorbidity, Obesity, Osage language	Altered Intercellular Communication	The degree of inflammation, which seems to worsen in cases of comorbidity (OSA and obesity), is likely to be responsible for the increased risk of developing cardiovascular events observed in these subjects, and therefore, it deserves to be elucidated even more.	20004360
Inflammation, Primary malignant neoplasm, Crohn Disease	Altered Intercellular Communication	Significant morbidity can result from perineal wounds, particularly if the tissue has been partially devitalized after radiotherapy and extensive resection for cancer or chronic inflammation which may occur in Crohn's disease.	20004444
Inflammation, Growth Disorders	Altered Intercellular Communication	Stunting, adiposity, and low-grade inflammation in African adolescents from a township high school.	20005466
Inflammation, Growth Disorders	Altered Intercellular Communication	An association between adiposity and stunting and between adiposity low-grade inflammation was found in this study.	20005466
Osteopenia	Altered Intercellular Communication	Our data therefore suggest that in bone cells of CF patients, the loss of CFTR activity may result in an increased inflammation-driven bone resorption (through both the reduced OPG and increased PGE(2) production), and thus might contribute to the early bone loss reported in young children with CF.	20005786
Inflammation, Hepatitis B	Altered Intercellular Communication	Hepatitis B virus overexpresses suppressor of cytokine signaling-3 (SOCS3) thereby contributing to severity of inflammation in the liver.	20005910
Hepatitis	Altered Intercellular Communication	Increased expression of SOCS3 protein was identified in liver specimens from patients with chronic HBV-infection and this correlated with the severity of liver inflammation.	20005910
vascular inflammations	Altered Intercellular Communication	Increasing evidence indicates that CD40-CD40 ligand interactions constitute an important mediator for vascular inflammation.	20006362
Inflammation, Tumor necrosis	Altered Intercellular Communication	Chronic inflammation, characterized by increased serum levels of tumor necrosis factor-alpha, interleukin-6, C-reactive protein, and plasminogen activator inhibitor-1, and the presence of inflammatory-related diseases, are seen commonly in aging.	20006787
Inflammation	Altered Intercellular Communication	Both the dysregulation of immune cells and phenotypic changes in parenchymal cells may contribute to chronic inflammation in aging.	20006787
Inflammation	Altered Intercellular Communication	Oxidative stress, via activation of p38 and c-Jun N-terminal kinase and induction of cell senescence, is likely to play a critical role in inflammation.	20006787
Inflammation	Altered Intercellular Communication	Endoplasmic reticulum stress also may be present in aging and be involved in inflammation.	20006787
Inflammation	Altered Intercellular Communication	Advanced glycation end products also are important contributors to inflammation in aging.	20006787
glycation, Inflammation	Altered Intercellular Communication	Because the kidney is a major site for the excretion, and perhaps the degradation, of advanced glycation end products and small inflammatory molecules, reduced renal function in aging may promote oxidative stress and inflammation.	20006787
Inflammation	Altered Intercellular Communication	Chronic inflammation in turn may potentiate the initiation and progression of lesions in the aging kidney.	20006787
Inflammation	Altered Intercellular Communication	Aging is characterized by increasing inflammation and oxidant stress (OS).	20006791
Reduced Device Function, Inflammation	Altered Intercellular Communication	The build-up of AGEs with reduced renal function could contribute to inflammation, increased oxidant stress, and accumulation of AGEs in aging.	20006791
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	Patients with uveitis at 4 academic ocular inflammation subspecialty practices.	20006905
Inflammation	Altered Intercellular Communication	Data obtained in mice, together with the fact that AGP levels largely exceeded gimatecan plasma concentrations, suggest that the increased gimatecan levels in patients with high AGP levels are not related to the binding of the drug to AGP with consequent reduced tissue drug distribution, but possibly to other mechanism associated with inflammation being AGP simply a marker of the inflammation process.	20007015
Inflammation, Chronic Kidney Diseases, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Chronic kidney disease (CKD) increases systemic inflammation, which is implicated in development and maintenance of atrial fibrillation (AF); therefore, we hypothesized that the prevalence of AF would be increased among nondialysis patients with CKD.	20007681
Inflammation, Hyperglycemia, Diabetes Mellitus	Altered Intercellular Communication	Poor glycemic control in Type 1 diabetes (T1DM) causes long-term cardiovascular complications, at least in part via chronic, low-grade inflammation associated with recurrent hyperglycemia.	20007854
Airway structure	Altered Intercellular Communication	Fraction of exhaled nitric oxide (Fe(NO)) is regarded as a marker of airway inflammation.	20007926
Airway structure	Altered Intercellular Communication	The results also support the hypothesis that increased level of Fe(NO) among subjects without respiratory symptoms is a sign of subclinical airways inflammation.	20007926
Lymphohistiocytosis, Hemophagocytic	Altered Intercellular Communication	Hemophagocytic lymphohistiocytosis (HLH), which has many genetic causes, is characterized by multi-system inflammation.	20008190
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Although clinical studies have suggested a link between inflammation markers and atrial fibrillation (AF), it is still unclear whether local immunologic responses actually exist in human atria during AF.	20009387
Inflammation	Altered Intercellular Communication	Of these patients, 7 developed BRONJ with BP treatment, after tooth extraction or acute dental inflammation.	20009460
Inflammation	Altered Intercellular Communication	Treating dental inflammation before prescribing BP prevented the development of BRONJ.	20009460
Inflammation	Altered Intercellular Communication	We focused our investigation on determining VEGF gene expression and characterizing the different genes, mediators of inflammation and adipogenesis, and which are known to play a relevant role in angiogenesis regulation.	20011601
Inflammation, Mass in breast	Altered Intercellular Communication	Patients typically present with a firm breast mass, often associated with inflammation of the overlying skin.	20012050
Inflammation	Altered Intercellular Communication	The expression of pro-inflammatory cytokines such as IL-8, IL-6, MIP-1b, and MCP-1 suggests that T and B cells, macrophages and neutrophils modulate joint inflammation by an immune response.	20012054
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	We also explore the role of diabetes mellitus in the pathogenesis of malakoplakia and compare the relationship between malakoplakia and xanthogranulomatous inflammation, which are closely related to each-other on both clinical and morphologic grounds.	20012360
Inflammation, diabetic, Diabetes Mellitus, Diabetic Retinopathy, Cardiac complication	Altered Intercellular Communication	Significantly elevated levels of hsCRP in diabetic patients with the presence of diabetic retinopathy compared with patients without diabetic retinopathy providing a link between inflammation and the development of microvascular complication of diabetes.	20012460
Inflammation, Complications of Diabetes Mellitus	Altered Intercellular Communication	The link between the antioxidant concentration, inflammation and the development of diabetes complications needs further longitudinal studies in order to confirm our findings.	20012460
Inflammation, Erythema Infectiosum	Altered Intercellular Communication	These data suggest parvovirus B19 infection may be associated with chronic inflammation in some women after the third decade of life.	20012869
Tumor necrosis, Inflammation, Antiphospholipid Syndrome	Altered Intercellular Communication	Increased level of tumor necrosis factor-a in patients with antiphospholipid syndrome: marker not only of inflammation but also of the prothrombotic state.	20012959
Inflammation, Thrombosis, Antiphospholipid Syndrome	Altered Intercellular Communication	Connections between inflammation and thrombosis are intriguing, especially in a condition such as an antiphospholipid syndrome (APS), a disease characterized by immune-mediated thrombosis.	20012959
Trismus, Inflammation, Pain Distress Question	Altered Intercellular Communication	After treatment one patient developed a grade 2 trismus, another showed grade 3 abacterial salivary gland inflammation with severe pain requiring opioid medication.	20013086
Neurodegenerative Disorders, Primary malignant neoplasm, Inflammation, Disease	Altered Intercellular Communication	Recent studies have shown that the heat-shock response (HSR) contributes to cytoprotection in a number of human diseases including inflammation, cancer, aging, and neurodegenerative disorders.	20013185
Inflammation, Neoplasms, Specimen Source Codes - Abscess, Ulcer, Erectile dysfunction	Altered Intercellular Communication	In the 18th century, theories about the main factors inducing impotence saw it as an abnormal state of the fibers, a defect in the solid or liquid substances or a bad structure (tumor, inflammation, abscess, ulcer or foreign body).	20013735
Inflammation	Altered Intercellular Communication	ST2 has been proposed to be a regulator of inflammation and Th1/Th2 balance.	20014018
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is an established risk factor for atherosclerosis.	20014193
Inflammation, Hyperactive behavior, Atherosclerosis	Altered Intercellular Communication	The findings of hyperactive NF-kappaB in aortas may provide a diagnostic parameter for the inflammation that is associated with and may cause atherosclerosis.	20014193
allergic inflammation	Altered Intercellular Communication	Cholesterol promotes Th2 immunity and allergic inflammation in rodents; whether this occurs in humans is unclear.	20015326
Hyperglycemia, Inflammation	Altered Intercellular Communication	In postcardiac-arrest (PCA) patients, hyperglycemia is a factor reflecting an unfavorable outcome, and might be caused by the inflammation and stress of "sepsis-like" syndrome.	20015588
Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	Alveolar cell senescence exacerbates pulmonary inflammation in patients with chronic obstructive pulmonary disease.	20016134
ARCN1 gene, Inflammation	Altered Intercellular Communication	We tested the hypothesis that alveolar cell senescence contributes to the chronic inflammation that affects the lungs of COPD patients.	20016134
Inflammation, BALT lymphoma	Altered Intercellular Communication	BALT lymphomas are associated with chronic inflammation, and they are often asymptomatic.	20016430
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease is frequently associated with protein-energy wasting related to chronic inflammation and a resistance to anabolic hormones such as insulin and growth hormone (GH).	20016461
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease is frequently associated with protein-energy wasting related to chronic inflammation and a resistance to anabolic hormones such as insulin and growth hormone (GH).	20016461
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease is frequently associated with protein-energy wasting related to chronic inflammation and a resistance to anabolic hormones such as insulin and growth hormone (GH).	20016461
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic inflammation associated with chronic kidney disease predicts all-cause and cardiovascular mortality in hemodialysis patients.	20016471
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Also inflammation of bronchial mucosa during chronic obstructive pulmonary disease (COPD) is likely combined with inflammatory involvement of nasal mucosa.	20017434
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	The SF and serum CCL2/MCP-1 concentrations are significantly greater in RA than in OA and in hda-RA than in mda-RA; increased SF over serum concentrations suggest that CCL2/MCP-1 is mainly produced locally by activated cells where it may exacerbate and sustain inflammation by attracting proinflammatory leukocytes, predominantly monocytes (Tab.	20017457
Inflammation, Critical Illness	Altered Intercellular Communication	Although associated with systemic inflammation, the metabolic features of hypovitaminosis C in acutely hospitalized, non-critically ill patients are more consistent with deficiency than with tissue redistribution.	20018480
Inflammation	Altered Intercellular Communication	Aging is one factor believed to contribute to processes that underlie chronic low-grade inflammation in older adults.	20018825
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Functional annotation analysis revealed prominent regulation of hypoxia-associated biological processes in NSC, including angiogenesis, fibrosis, and inflammation.	20019191
Inflammation, conjunctiva	Altered Intercellular Communication	Increased tear inflammation seemed to coexist with loss of conjunctival epithelial cohesiveness and increased collagenolytic activity, which may explain the conjunctival laxity observed in patients with conjunctivochalasis.	20019361
Inflammation, Hypoxia, Anemia	Altered Intercellular Communication	Hepcidin synthesis is suppressed by anemia, hypoxia and erythropoiesis, and induced by inflammation.	20019408
Inflammation, hepcidin, Anemia	Altered Intercellular Communication	Inflammatory cytokines, such as interleukin-6 (IL-6), increase the synthesis of hepcidin, resulting in anemia of inflammation (AI).	20019408
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Type 2 diabetes mellitus (T2D) is predicted by central obesity and circulating adipokines regulating inflammation.	20019678
Inflammation, Tumor necrosis, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Subjects with T2D had higher VAT expression of molecules regulating inflammation (tumor necrosis factor-alpha (TNFalpha), macrophage inflammatory protein (MIP), interleukin-8 (IL-8)).	20019678
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	In summary, VAT in T2D expresses higher levels of adipokines involved in inflammation.	20019678
Inflammation, Back Pain	Altered Intercellular Communication	A 19-year-old female patient with back pain was examined using [(18)F]-FDG-PET to detect the source of inflammation.	20020137
vascular inflammations	Altered Intercellular Communication	A follow-up scan showed residual uptake of [(18)F]-FDG in the thoracic aorta suggesting subclinical vascular inflammation.	20020137
Communicable Diseases, Inflammation	Altered Intercellular Communication	We describe the first case of cutaneous infection caused by Chaetomium atrobrunneum and Clavispora lusitaniae in a one-and-a-half-year-old boy with acute and severe inflammation around his left eyelid.	20020214
Inflammation	Altered Intercellular Communication	These observations indicate that adiposity is associated with inflammation and endothelial activation in very early childhood.	20020578
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation plays a role in the development of Alzheimer's disease (AD).	20021370
Inflammation, Hypersensitivity, Infection	Altered Intercellular Communication	Thus, it is practically unknown how a healthy active lifestyle could affect low-grade inflammation processes, infections or allergies in young persons.	20021690
Inflammation, Alopecia	Altered Intercellular Communication	In women without systemic inflammation or other underlying disorders, serum ferritin levels below or equal to 30 ng/mL are strongly associated with telogen hair loss.	20021982
Inflammation	Altered Intercellular Communication	Inflammation could not account for increased LS since initial liver enzyme counts were only slightly elevated and did not change significantly.	20022130
Inflammation	Altered Intercellular Communication	Physical examination found visual acuity reduced to light perception without sign of anterior inflammation.	20022662
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	The course of COPD is punctuated by exacerbations, which further increase systemic inflammation, but the risk of vascular events in the postexacerbation period has never been defined.	20022970
Autoimmune Diseases, Myocarditis	Altered Intercellular Communication	Myocardial inflammation in autoimmune diseases: investigation by cardiovascular magnetic resonance and endomyocardial biopsy.	20025587
Autoimmune Diseases, Myocarditis	Altered Intercellular Communication	Myocardial inflammation often coexists with different types of autoimmune diseases.	20025587
Inflammation	Altered Intercellular Communication	In myocardial specimens, histology revealed inflammation in 5/10 (50%) and PCR documented viral or microbial genomes in 8/10 (80%).	20025587
Autoimmune Diseases, Myocarditis, cardiac symptom	Altered Intercellular Communication	Myocardial inflammation is a common finding in patients with autoimmune diseases and cardiac symptoms.	20025587
ARCN1 gene, Inflammation	Altered Intercellular Communication	Treatment with VIP may help to decrease the chronic inflammation in the lung of COPD patients.	20026142
Host defense, Inflammation	Altered Intercellular Communication	Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice.	20026663
Communicable Diseases, Inflammation	Altered Intercellular Communication	PGRN-deficient mice failed to clear Listeria monocytogenes infection as quickly as WT and allowed bacteria to proliferate in the brain, with correspondingly greater inflammation than in WT.	20026663
Inflammation, GRN wt Allele	Altered Intercellular Communication	Thus, PGRN is a key regulator of inflammation and plays critical roles in both host defense and neuronal integrity.	20026663
Inflammation, Frontotemporal dementia	Altered Intercellular Communication	FTD associated with PGRN insufficiency may result from many years of reduced neutrotrophic support together with cumulative damage in association with dysregulated inflammation.	20026663
Crohn Disease, Inflammation	Altered Intercellular Communication	Over the last some years the increasing knowledge on the pathogenesis of Crohn's disease led to the development of a number of biological agents targeting specific molecules involved in gut inflammation, first of all TNF-alpha and its receptors.	20028325
Inflammation, Non-compliance, Diarrhea	Altered Intercellular Communication	The reasons for dropout were side effects (diarrhea [n = 1], gastric symptoms [n = 9], and inflammation of the mouth [n = 1]) or non-compliance (n = 3).	20028640
Carcinoma of lung	Altered Intercellular Communication	IRAK-1 is a novel inflammation-related marker and a potential target for lung cancer chemopreventive strategies.	20028769
Inflammation	Altered Intercellular Communication	Excision biopsy showed granulomatous inflammation involving the lymphatics.	20029155
Inflammation, Chronic anterior uveitis	Altered Intercellular Communication	Topical and intravitreal corticosteroids were effective in reducing acute inflammation, yet 2 patients went on to have chronic anterior uveitis.	20029490
Inflammation, Hypoxia, Anemia, hepcidin	Altered Intercellular Communication	Hepcidin is a small defensin-like peptide, the production of which by hepatocytes is modulated in response to anemia, hypoxia, or inflammation.	20030521
Inflammation	Altered Intercellular Communication	In addition, the presence of low-grade inflammation, more pronounced in anuric patients, and functional iron deficiency may also contribute to the elevated hepcidin.	20030521
Pneumonitis	Altered Intercellular Communication	Lymphocytes play a crucial role in lung inflammation.	20030671
Sepsis, Inflammation, Specimen Type - Fistula, Hilar lymph node	Altered Intercellular Communication	Our experience would suggest that in very carefully selected cases where bronchopulmonary contamination from the fistula is minimal or absent, there is no associated inflammation of the tracheobronchial tree and the patient is stable from a respiratory point of view without evidence of sepsis, there may be a role for a trial of conservative management.	20030856
Pulmonary failure, Inflammation	Altered Intercellular Communication	Patients with early elevated biomarkers of inflammation exhibited higher NGAL, more pulmonary failure, and greater resource utilization.	20031165
Intraocular inflammation	Altered Intercellular Communication	Severe intraocular inflammation after intravitreal injection of bevacizumab.	20031229
Intraocular inflammation	Altered Intercellular Communication	To report 5 cases of severe intraocular inflammation that developed after an intravitreal injection of the same lot of bevacizumab.	20031229
Intraocular inflammation	Altered Intercellular Communication	Incidence of intraocular inflammation, results of bacterial cultures, best-corrected visual acuity (BCVA), and endothelial cell density.	20031229
Intraocular inflammation, Inflammation	Altered Intercellular Communication	Five (14.3%) of the 35 cases had severe intraocular inflammation, and the inflammation had some characteristics of toxic anterior segment syndrome (TASS).	20031229
Staphylococcus epidermidis, Vitreous inflammatory cells	Altered Intercellular Communication	Early Staphylococcus epidermidis postoperative endophthalmitis developed 3 days later in the right eye (injected first) with intense vitreous inflammation, limiting visual acuity to light perception.	20031257
Inflammation, Pathological fracture of vertebra due to osteoporosis, Acute onset pain	Altered Intercellular Communication	Kyphoplasty to treat an osteoporotic vertebral fracture was followed by acute pain with an inflammatory time pattern and laboratory evidence of inflammation.	20031466
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	A biopsy of the lesion disclosed moderate nonspecific inflammation, with no microorganisms or evidence of malignancy.	20031466
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Our findings highlight biological pathways that may be important in regulation of inflammation underlying cardiovascular disease.	20031576
Inflammation, Coronary Artery Disease, Atherosclerosis	Altered Intercellular Communication	Because inflammation is considered of crucial importance in the development of atherosclerosis, we aimed to evaluate whether prolactin levels are associated with the occurrence of coronary artery disease (CAD).	20031611
Vasculitis	Altered Intercellular Communication	Recent studies suggest that C-reactive protein (CRP) reflects vascular wall inflammation and can predict adverse cardiac events.	20031768
Inflammation, Necrosis	Altered Intercellular Communication	Five patients (21%) developed marginal necrosis within the fragments of the cut off flaps requiring cutaneous plasty; an inflammation of the recipient site occurred in 5 cases (21%).	20032531
Pneumonitis, Atherosclerosis	Altered Intercellular Communication	In order to explain these effects (today the causality of the relationship is certain) there are many possible factors, particularly regarding particulate exposures: an increase in cardiovascular risk biomarkers (fibrinogen, white blood cells, and platelets), atherosclerosis, chronic inflammation of lung tissues increased by acute exposure, etc.	20032841
Inflammation, Impaired cognition, Encephalitis	Altered Intercellular Communication	Investigation of HIV-1-associated alterations in brain protein turnover by the ubiquitin-proteasome system was performed by (1) determining proteasome subunit changes associated with persistent brain inflammation due to HIV-1; (2) determining whether these changes are related to HIV-1 neurocognitive disturbances, encephalitis, and viral loads; and (3) localizing proteasome subunits in brain cells and synapses.	20035054
Hypophysitis, CTCAE	Altered Intercellular Communication	Primary hypophysitis is believed to be a chronic inflammation of the pituitary tissue caused by the autoimmune mechanism.	20035143
Pneumonitis	Altered Intercellular Communication	Interleukin 1B (IL1B) is involved in pulmonary inflammation induced by environmental or occupational toxins.	20035239
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Chronic inflammation has been implicated in the development of lung cancer.	20035239
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Angiogenesis is an essential event in the development of synovial inflammation in rheumatoid arthritis (RA).	20035291
Degenerative polyarthritis, Inflammation, Refractory anemias	Altered Intercellular Communication	Synovial tissue samples were obtained at surgery from patients with osteoarthritis (OA) and RA, and subjected to immunohistochemistry to investigate the expression and distribution of vasohibin-1 relevant to the degree of synovial inflammation.	20035291
Inflammation	Altered Intercellular Communication	In synovial tissue, there was a significant correlation between the expression of vasohibin-1 and histological inflammation score (p=0.002, r=0.842).	20035291
Inflammation, atherosclerotic	Altered Intercellular Communication	Endothelin (ET)-1 has been implicated in the atherosclerotic process and during inflammation.	20036012
Ischemic stroke	Altered Intercellular Communication	Excitatory amino acids and monoaminergic neurotransmitters in cerebrospinal fluid of acute ischemic stroke patients.	20036703
Brain Injuries	Altered Intercellular Communication	Improved insight in the role of neurotransmitters in acute cerebral ischemic injury may be fundamental for the successful development of novel therapeutic approaches.	20036703
Ischemic stroke, Cerebrovascular accident	Altered Intercellular Communication	We investigated excitatory amino acids and monoaminergic neurotransmitters in cerebrospinal fluid (CSF) of acute ischemic stroke patients and their relation to stroke characteristics.	20036703
Calculus of prostate, Inflammation, Prostate	Altered Intercellular Communication	Prostatic calculi are common and are associated with inflammation of the prostate.	20037598
Inflammation, Carcinogenesis	Altered Intercellular Communication	Recently, it has been suggested that this inflammation may be associated with prostate carcinogenesis.	20037598
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Inflammation and oxidative stress in end-stage renal disease patients treated with hemodialysis or peritoneal dialysis.	20037892
palladium, HD Term Type, Inflammation	Altered Intercellular Communication	HD and PD patients show similar degrees of inflammation and oxidative stress activation.	20037892
Granulomatous inflammation, Vasculitis, CTCAE, Necrosis	Altered Intercellular Communication	The anatomic pathology is characterized by vasculitis, granulomatous inflammation with multinuclear giant cells and necrosis.	20038886
Inflammation	Altered Intercellular Communication	The levels of all specific ACPAs were elevated in synovial fluid, suggesting that there is local antibody production and/or retention of ACPAs at the site of inflammation governed by RA-predisposing genes.	20039432
Nonalcoholic Steatohepatitis, Inflammation, Fatty degeneration	Altered Intercellular Communication	A nonalcoholic steatohepatitis activity index was defined which scored the grade of disease activity between 0 and 12 according to four histologic features: steatosis, hepatocyte ballooning, portal inflammation, and lobular inflammation.	20039768
Uremia, Inflammation	Altered Intercellular Communication	Uremia is associated with inflammation and release of cytokines by lymphomonocytes.	20040350
ARCN1 gene, Inflammation	Altered Intercellular Communication	Our results support the hypothesis that chronic inflammation and oxidative burden in COPD can lead to DNA damage of the lung epithelial barrier cells, detected at the Microsatellite DNA level.	20040382
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We conclude that systemic inflammation is relevant to the process that leads to functional loss in older persons and can be validly measured through biologically informed summary of inflammatory markers.	20041734
Inflammation	Altered Intercellular Communication	The chemokine CXCL13 is known to dictate homing and motility of B cells in lymphoid tissue and has been implicated in the formation of ectopic lymphoid tissue in chronic inflammation.	20042073
Inflammatory abnormality of the eye	Altered Intercellular Communication	Given sufficient time, mycophenolate mofetil was effective in managing ocular inflammation in approximately half of the treated patients.	20042178
Inflammation	Altered Intercellular Communication	We hypothesized that chronic inflammation is associated with altered DNA methylation levels within the PTGS2 promoter, with effects on COX-2 mRNA expression.	20042743
Inflammation	Altered Intercellular Communication	These findings suggest that the chronic persistence of the biofilm and inflammation may be associated with epigenetic changes in local tissues at the biofilm-gingival interface.	20042743
Inflammation, Refractory anemias, Rheumatoid Arthritis, Crohn Disease, Comorbidity	Altered Intercellular Communication	Systemic inflammation such as rheumatoid arthritis (RA) and Crohn's disease (CD) may be responsible for vascular comorbidity.	20042802
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histopathological examination revealed a proteinaceous mass consistent with drug precipitate enveloped by fibrosis and mild inflammation.	20043767
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	No association was detected between CCL3L1 copy numbers and histological grades of inflammation or stages of fibrosis.	20044164
Inflammation, Intracranial Aneurysm	Altered Intercellular Communication	Gene expression profiles in human ruptured and unruptured intracranial aneurysms: what is the role of inflammation?	20044533
Inflammation, Rupture	Altered Intercellular Communication	Inflammation may participate in the healing process within IA while playing a protective role against IA rupture.	20044533
Inflammation, Primary malignant neoplasm, Pathology, Cardiovascular Diseases, Immune dysregulation	Altered Intercellular Communication	Dysregulations of the KKS are likely to be involved in pathologies such as inflammation, cancer and cardiovascular diseases.	20045189
Inflammation, Neoplasms	Altered Intercellular Communication	The roles of chronic inflammation, immunosuppression, and smoking in the pathogenesis of this tumour are briefly discussed.	20045232
Inflammation, Tissue Adhesions	Altered Intercellular Communication	Peri-cholecystic adhesions including cholecysto-enteric fistulae and acute inflammation were the main reason for difficult dissection.	20046176
Inflammation	Altered Intercellular Communication	The data support the hypothesis of an inverse association between GH/IGF-I signalling and inflammation, and suggest that the relationship between the IGF-I and inflammation might be more predominant in healthy individuals with a low inflammatory activity.	20047081
Arthritis, Chondritis of pinna, Nasal chondritis, Inflammatory abnormality of the eye	Altered Intercellular Communication	Characteristic features include auricular chondritis, arthritis, nasal chondritis, ocular inflammation, respiratory tract involvement and audiovestibular damage.	20049455
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation is a relatively common finding in routine aspiration cytology of lymph nodes.	20049975
Inflammation, Asteroids	Altered Intercellular Communication	A transbronchial fine-needle aspiration biopsy (FNAB) of a paratracheal lymph node showed granulomatous inflammation and numerous multinucleated giant cells containing asteroid bodies.	20049975
Pain Distress Question, Inflammation	Altered Intercellular Communication	This episode was prolonged lasting for approximately 10 weeks and required hospitalization for the management of pain and control of inflammation.	20051757
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	No correlations were found between capillary density and plasma markers of adiposity, inflammation or endothelial dysfunction.	20051903
Inflammation, Exophthalmos, Paranasal Sinus Neoplasms	Altered Intercellular Communication	We rarely encounter patients with proptosis, however, it is known that inflammation and extension of paranasal sinus tumors may cause this condition.	20053515
Inflammation	Altered Intercellular Communication	Diffusion-weighted analysis and MR spectroscopy were consistent with focal inflammation.	20054691
Inflammation, Asthma	Altered Intercellular Communication	The initial symptoms included bronchial asthma and inflammation of the ethmoid sinuses.	20054752
Pain Distress Question, Solitary Osteochondroma, Bursitis, Femoracetabular Impingement, Abnormal degeneration	Altered Intercellular Communication	Although solitary osteochondromas have been linked with bursal inflammation and pain, compression on neurovascular structures, and malignant degeneration, they have not previously been associated with femoral acetabular impingement.	20055356
Inflammation, Alopecia, CTCAE	Altered Intercellular Communication	During her 50s, however, the patient developed new abnormalities with patchy scarring alopecia and perifollicular inflammation.	20055845
Acute Lung Injury, Critical Illness, Lung Injury, Pneumonitis	Altered Intercellular Communication	We compared the effect of conventional with lower tidal volumes on pulmonary inflammation and development of lung injury in critically ill patients without ALI at the onset of mechanical ventilation.	20055989
Inflammation	Altered Intercellular Communication	In this study, we investigated the potential for quantifying plaque inflammation by targeting this receptor.	20056222
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Elevated plasma levels of C-reactive protein (CRP), a marker of inflammation, are associated with an increased risk of cancer, but it is unclear whether this association is causal.	20056955
Inflammation	Altered Intercellular Communication	Lipocalin-2/neutrophil gelatinase-B associated lipocalin (Lcn2/NGAL) is involved in the transport of iron and seems to play an important role in inflammation.	20057160
Inflammation, Fever, CTCAE, Periaortitis	Altered Intercellular Communication	Persistent high fever and systemic inflammation induced by percutaneous coronary intervention-related periaortitis.	20057898
Inflammation, Fever, CTCAE, Periaortitis	Altered Intercellular Communication	We report a very rare case that suggests persistent high fever and systemic inflammation might be caused by periaortitis induced by coronary catheterization including percutaneous coronary intervention.	20057898
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Damage to trabecular meshwork cells (TMC) and retinal ganglion cells (RGC), involving inflammation and apoptosis mechanisms, has been proved in glaucoma.	20057902
Inflammation, Humor	Altered Intercellular Communication	Inflammation and apoptosis marker levels increase with smoking in the aqueous humor and plasma samples of POAG women.	20057902
Inflammation	Altered Intercellular Communication	We present the case of a patient with primary SRC complicated by the development of acute inflammation of the appendix.	20058100
Inflammation	Altered Intercellular Communication	The appendix was notably thickened with an ulcerated wall containing sinus tracts, chronic inflammation, and scarring.	20058100
Inflammation, Hyperplasia	Altered Intercellular Communication	Histological analysis consistently demonstrated chronic nonspecific inflammation with synovial hyperplasia, proliferation of vessels and fibroblasts, and increased amount of extracellular matrix.	20058278
Inflammation, Periodontitis, Diabetes Mellitus	Altered Intercellular Communication	Inflammation and iNOS expression were more prominent in the gingiva of the patients with both diabetes and periodontitis.	20059423
Inflammation, Immune-mediated	Altered Intercellular Communication	CS is often associated with collagen deposition or chronic inflammation in other segments of the gastrointestinal tract as well as other immune-mediated disorders.	20060071
Inflammation, Tissue Adhesions, Comorbidity	Altered Intercellular Communication	The technique was uniformly applicable irrespective of gender, age, time of presentation, grade of inflammation, adhesions or any comorbidity.	20060076
Inflammation	Altered Intercellular Communication	Diffuse large B-cell lymphoma associated with chronic inflammation as an incidental finding and new clinical scenarios.	20062008
Inflammation, Neoplasms	Altered Intercellular Communication	Diffuse large B-cell lymphoma that develops in the setting of long-standing chronic inflammation is typically associated with Epstein-Barr virus, and usually presents as tumor mass involving body cavities, as in pyothorax-associated lymphoma.	20062008
Inflammation, Lymphoma, Chronic inflammation, B-Cell Lymphomas	Altered Intercellular Communication	The last feature supports the hypothesis that the lymphoma has arisen in a setting of 'local immunodeficiency' as a result of long-standing chronic inflammation in an enclosed space, a characteristic pathogenetic mechanism of diffuse large B-cell lymphoma associated with chronic inflammation.	20062008
Inflammation	Altered Intercellular Communication	This report shows that it is possible for an extended epidural cystic mass that occurs in Baastrup's disease to change over time through peripheral inflammation into a cyst-containing fibrotic mass.	20063020
Airway structure, Bronchial Hyperreactivity	Altered Intercellular Communication	IL-13 has been implicated in the development of airway inflammation and hyperresponsiveness.	20064211
Inflammation, Tuberculosis	Altered Intercellular Communication	Six patients had tuberculosis and 8 were confirmed with chronic inflammation or benign lesion.	20064673
Inflammation, Carcinoma of lung, Tuberculosis	Altered Intercellular Communication	Based on the RT-nested PCR examination, 41 of 53 patients were positive for the MAGE gene: 34 of 39 patients had lung cancer; 5 of 6 patients had tuberculosis; and 2 of 8 patients had chronic inflammation or benign lesion.	20064673
Inflammation, Heart failure, physiopathological	Altered Intercellular Communication	These findings suggest that IL-6 may underlie the pathogenetic link between inflammation, LV dysfunction and incipient heart failure.	20064818
Gastrointestinal inflammation	Altered Intercellular Communication	The Regenerating gene (REG) Ialpha protein, a trophic and/or anti-apoptotic factor, is important in the pathophysiology of gastrointestinal inflammation.	20065946
Refractory anemias, Inflammation	Altered Intercellular Communication	Most recent studies show that anti-TNFa medication suppresses inflammation and reduces overall activity of RA.	20066426
Refractory anemias, Inflammation	Altered Intercellular Communication	The results of the study expand perspectives of the use of MPV in conditions associated with high-grade inflammation, particularly RA, for monitoring anti-inflammatory treatment.	20066426
Sepsis, Inflammation	Altered Intercellular Communication	Patients with sepsis having a high degree of inflammation did not show a positive correlation between the severity of the disease and the changes of Mg.	20067167
Inflammation, Autofluorescence, Neoplasms	Altered Intercellular Communication	Newly developed autofluorescence (AF) imaging (AFI) endoscopy can detect AF emitted by the gastrointestinal wall and may reliably detect tumors or inflammation that block AF.	20068309
Inflammation	Altered Intercellular Communication	Low-grade inflammation, more pronounced in anuric patients may also contribute to elevated NGAL.	20068352
Vasculitis, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome is associated with intravascular inflammation, as determined by increased levels of inflammatory biomarkers and an increased risk of ischemic atherothrombotic events.	20069077
Vasculitis, Thrombosis	Altered Intercellular Communication	Evidence suggests that atherothrombosis and intravascular inflammation share predictive biomarkers, including high-sensitivity C-reactive protein, CD40 ligand, P-selectin, and N-terminal pro-brain natriuretic peptide.	20069077
Inflammation	Altered Intercellular Communication	Transforming growth factor beta (TGFbeta) is important in inflammation, angiogenesis, reepithelialization and connective tissue regeneration during wound healing.	20069132
Inflammation, Dental Plaque	Altered Intercellular Communication	The hygiene level was evaluated with Silness and Loe plaque index (PI) and inflammation level with Loe and Silness gingival index (GI).	20069965
Airway structure	Altered Intercellular Communication	Although corticosteroids reduce airway inflammation, in vitro they inhibit proliferation in only non-asthma ASM cells by reducing cyclin D1.	20070588
Inflammation, MS gene	Altered Intercellular Communication	Acute symptomatic inflammation is a main feature of multiple sclerosis but pathophysiological processes underlying total or partial recovery are poorly understood.	20071121
Steatohepatitis, Inflammation, Obesity	Altered Intercellular Communication	Furthermore, DBC1-deficient mice were protected from HFD-induced liver steatosis and inflammation, despite the development of obesity.	20071779
Heart Diseases, Inflammation, Hypertension, CTCAE, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	The role of inflammation in maintenance of paroxysmal atrial fibrillation (PAF) in patients with hypertension and no other heart disease has not been fully elucidated yet.	20072146
Airway structure, Asthma	Altered Intercellular Communication	TLR-mediated inflammatory signals contribute to the development and severity of asthma and are not reduced by glucocorticoid treatment, which suggests that a TLR-specific antagonist and glucocorticoid are required for the effective control of airway inflammation in asthmatics.	20072849
Asthma	Altered Intercellular Communication	The authors undertook this study to explore the hypothesis that TLR-mediated inflammatory signals are important from the perspective of asthma management.	20072849
Airway structure, Asthma	Altered Intercellular Communication	TLR-mediated inflammatory signals contribute to the development and severity of asthma and are not reduced by glucocorticoid treatment, which suggests that a TLR-specific antagonist and glucocorticoid are required for the effective control of airway inflammation in asthmatics.	20072849
Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Unipolar Depression, Minimal Disseminated Disease	Altered Intercellular Communication	To determine levels of inflammation (ferritin, transferrin and fibrinogen) in major depression (MDD) and comorbid cardiovascular disease (CVD) in an adult population.	20073117
Inflammation, Neoplasms, Craniopharyngioma, Epithelial cyst	Altered Intercellular Communication	However a good prognostic factor in craniopharyngiomas was observed in older female patients with complete exeresis, small tumors, external epithelium cysts, edematous stroma, inflammation, and absence of atypical cell and mitosis.	20073441
Inflammation, Lung diseases	Altered Intercellular Communication	Because many lung diseases cause inflammation at different sites of the lung, fractionated sampling of EBC can reduce variability and maintain an anatomical allocation of the exhaled biomarkers.	20073556
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Magnetic resonance spectroscopic imaging (1H-MRSI) and dynamic contrast-enhanced magnetic resonance (DCE-MRI): pattern changes from inflammation to prostate cancer.	20073578
Prostatic Intraepithelial Neoplasias, Acute and chronic inflammation, Prostate carcinoma	Altered Intercellular Communication	To assess (1)H-magnetic resonance spectroscopic imaging ((1)H-MRSI) and dynamic contrast-enhanced magnetic resonance (DCE-MRI) features in histologically confirmed prostatic chronic inflammation, prostatic intraepithelial neoplasia (PIN), low grade prostate cancer (LGPCa), and high grade prostate cancer (HGPCa).	20073578
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Ninety-six men were selected, who showed at histology a diagnosis of chronic inflammation (Group B), high grade (HG) PIN (Group C), or prostate cancer (LGPCa = Group D and HGPCa = Group E).	20073578
Autoimmune Diseases, Inflammation, Graft-vs-Host Disease	Altered Intercellular Communication	The well-documented involvement of heparanase in the process of inflammation and autoimmunity led us to investigate an association between HPSE gene single-nucleotide polymorphisms (SNPs) and the risk of GVHD.	20075159
Inflammation, Infection, Atherosclerosis	Altered Intercellular Communication	These results lend support to the notion that past or chronic exposure to common infections, perhaps by exacerbating inflammation, contributes to atherosclerosis.	20075350
Inflammation, Obesity	Altered Intercellular Communication	Ezetimibe not only reduced the serum LDL-C level but also improved glucose metabolism as well as obesity and inflammation markers.	20075600
Metabolic Syndrome X, Atherosclerotic lesion	Altered Intercellular Communication	Inflammation contributes to the development of atherosclerotic lesions in the metabolic syndrome.	20075843
Vitreous inflammatory cells, Hodgkin Disease	Altered Intercellular Communication	We describe a unique case of a patient with an established diagnosis of Hodgkin's lymphoma in clinical remission who later presented with apparent vitreous inflammation.	20076991
Granulomatous inflammation	Altered Intercellular Communication	A vitreous biopsy (including fortuitously some peripheral retinal fragments) exhibited granulomatous inflammation.	20076991
Chronic infectious disease, Inflammation, Traumatic injury, Malignant Neoplasms	Altered Intercellular Communication	None had a history or evidence of malignancy, chronic infection or inflammation, or recent trauma.	20077946
Whooping cough due to unspecified organism, Acute bronchitis, Bronchitis, Asthma, Respiratory Tract Infections	Altered Intercellular Communication	Daily hospital admissions for total respiratory infections or inflammations (RII), total bronchitis and asthma (BA), and total whooping cough and acute bronchitis (TWCAB) for various age groups and ethnicities were obtained for the Auckland Region and compared with climate parameters on daily, monthly and seasonal time scales.	20078568
Renal Insufficiency, Inflammation, Kidney Diseases	Altered Intercellular Communication	Inflammation has been related to renal disease in non-Hispanic whites, but there are limited data on the role of inflammation in renal dysfunction in African Americans in the community.	20078870
Inflammation, Kidney Diseases	Altered Intercellular Communication	The study of inflammation in the progression of renal disease in African Americans merits further investigation.	20078870
Inflammation	Altered Intercellular Communication	The reason might be related to the exposure and inflammation of the local vocal process cartilage.	20079098
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	(2) The intensity of IL-16 and CXCR3 were correlated with the index of clinical and pulmonary function that suggested pulmonary arterial inflammation might be one of the key factors associated with the progression of COPD, and inhibiting the pulmonary artery inflammation played an important role in prevention and cure of COPD.	20079227
Inflammatory Bowel Diseases, Inflammation, Arthritis, Collagen-Induced, Experimental Autoimmune Encephalomyelitis	Altered Intercellular Communication	The immunosuppressive function of regulatory B cells has been shown in several murine models of chronic inflammation, including collagen-induced arthritis, inflammatory bowel disease, and experimental autoimmune encephalomyelitis.	20079667
Inflammation, Uveitis	Altered Intercellular Communication	The FA intravitreal implant provided better control of inflammation in patients with uveitis compared with systemic therapy.	20079922
Inflammatory abnormality of the eye	Altered Intercellular Communication	Facial rosacea, lid margin, and ocular surface inflammation were documented by photography and graded in a masked fashion.	20079929
Inflammation, anatomical bulb	Altered Intercellular Communication	There was a significant correlation between serum immunoreactivity and facial rosacea (P = 0.009), lid margin inflammation (P = 0.040), and ocular Demodex infestation (P = 0.048), but not inferior bulbar conjunctival inflammation (P = 0.573).	20079929
Inflammation, anatomical bulb	Altered Intercellular Communication	There was a significant correlation of facial rosacea with lid margin inflammation (P = 0.016), but not with inferior bulbar conjunctival inflammation (P = 0.728).	20079929
Communicable Diseases, Inflammation, Vitreous opacities, Hypopyon	Altered Intercellular Communication	The 3 main kinds of recurrence were: (1) recurrent infection from recipient bed to graft, and once recurrent infection invaded the graft, the inflammation progressed more rapidly; (2) white mushroom-shaped hypopyon with anterior chamber recurrence; (3) infection in the posterior chamber and vitreous opacity on posterior segment recurrence.	20079930
AURKAIP1 gene, Inflammation	Altered Intercellular Communication	Corticosteroids reduce inflammation and restore both digestive enzyme and HCO(3)(-) secretion in patients with AIP by regenerating acinar cells and correcting CFTR localization in pancreatic duct cells.	20080093
Cataract, Intraocular inflammation	Altered Intercellular Communication	We report two cases of patients who presented with marked intraocular inflammation following uncomplicated cataract surgery.	20080318
CARCINOMA OF VULVA	Altered Intercellular Communication	The inflammation-based modified Glasgow Prognostic Score in patients with vulvar cancer.	20080329
Inflammation, CARCINOMA OF VULVA, Cachexia	Altered Intercellular Communication	To evaluate the prognostic potential of the modified Glasgow Prognostic Score (mGPS), known to reflect the degree of tumor-associated inflammation and cachexia, in patients with vulvar cancer.	20080329
CARCINOMA OF VULVA	Altered Intercellular Communication	Despite being associated with prognosis in a univariate analysis, mGPS cannot be used as an independent inflammation-based predictor for survival in patients with vulvar cancer.	20080329
Communicable Diseases, Infertility, Inflammation, Fallopian tube obstruction	Altered Intercellular Communication	We present a unique case of an EV infection of the fallopian tube resulting in inflammation, tubal obstruction, and infertility.	20080362
Communicable Diseases, Inflammation	Altered Intercellular Communication	Pulmonary surfactant phosphatidylglycerol inhibits respiratory syncytial virus-induced inflammation and infection.	20080799
Inflammation, Metabolic Diseases	Altered Intercellular Communication	Adipocytes synthesize galectin-3 whose deficiency protects from inflammation associated with metabolic diseases.	20080851
Degenerative polyarthritis, Inflammation, Osteoarthritis, Knee	Altered Intercellular Communication	To assess whether inflammation on ultrasound is predictive of clinical response to intraarticular (IA) corticosteroid injections in patients with knee osteoarthritis (OA).	20080918
Inflammation, ciliary vesicle	Altered Intercellular Communication	Microvascular endothelial dysfunction occurs early in the development of CV disease and is worsened by inflammation.	20080919
Inflammation, Anemia	Altered Intercellular Communication	We characterized the relationships between urinary hepcidin, iron status, anemia, and inflammation in 582 patients 65 years or older participating in the InCHIANTI (Invecchiare in Chianti, "Aging in the Chianti Area") study, a population-based study of aging in Tuscany, Italy.	20081092
Anemia of chronic disease, Anemia	Altered Intercellular Communication	Compared with nonanemic persons, urinary hepcidin (nanograms/milligram of urinary creatinine) was significantly lower in iron deficiency and inflammation anemia compared with no anemia or other anemia types.	20081092
Inflammation, hepcidin	Altered Intercellular Communication	Future studies should test whether hepcidin production becomes up-regulated only in situations of overt inflammation.	20081092
Inflammation	Altered Intercellular Communication	It occurs when soft tissue degenerates after a long period of chronic inflammation.	20081575
Inflammation	Altered Intercellular Communication	Likewise, during acute events of CAD, the number of circulating EPCs increases under the influence of vascular endothelial growth factor (VEGF) and systemic inflammation.	20082199
Inflammation, Occult chronic type B viral hepatitis, Infectious agent	Altered Intercellular Communication	The high-sensitivity CRP measurement enabled the detection of slight increases in the serum CRP level, which might reflect a minute inflammation by occult infection, and discriminated high-risk patients for infectious events.	20082574
Myocarditis	Altered Intercellular Communication	The delayed-enhancement CCTA showed patchy epicardial and mid-myocardial enhancement of the wall and apex, consistent with myocardial inflammation.	20083062
Myocarditis	Altered Intercellular Communication	Delayed-enhancement cardiac magnetic resonance imaging (CMR) performed the following day confirmed patchy, diffuse epicardial hyperenhancement of the lateral wall, septum, and apex consistent with myocardial inflammation.	20083062
Myocarditis, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Delayed-enhancement CCTA has potential utility for simultaneous evaluation of coronary arteries and myocardial inflammation in suspected myocarditis.	20083062
Inflammation	Altered Intercellular Communication	15-Deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)) is non-enzymatically produced from PGD(2) and plays roles in inflammation and oxidative stress responses.	20083106
Communicable Diseases, Inflammation, pathologic fistula	Altered Intercellular Communication	Fistulas are likely because of the presence of chronic inflammation or infection and may be seen at MR imaging, CT, or fluoroscopy.	20083595
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	In conclusion, our results suggest that those who react strongly to inflammation or who have a high host immune response, as reflected by extremely elevated plasma levels of CRP and SAA, are at a high risk to develop gastric cancer.	20083644
Dysphonia	Altered Intercellular Communication	Although most pediatric dysphonia can be attributed to benign nodules, our results show that inflammatory conditions and benign lesions other than nodules contribute to dysphonia and are often overlooked and undertreated.	20083783
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation was observed in the skin biopsy specimen.	20084402
Granulomatous inflammation, SYNOVITIS, GRANULOMATOUS, WITH UVEITIS AND CRANIAL NEUROPATHIES (disorder), Uveitis, Polyarthritis	Altered Intercellular Communication	The patient was diagnosed with Blau syndrome based on her family history, uveitis, granulomatous inflammation proved by skin biopsy, and polyarthritis.	20084402
Inflammation, Swelling, Joint tenderness	Altered Intercellular Communication	Eighteen patients with EOA underwent clinical examination for joint tenderness, bony swelling, and inflammation by two independent, blinded assessors.	20084443
Arthritis, Swelling, Joint tenderness	Altered Intercellular Communication	The inter-observer agreement was moderate for bony swelling and joint tenderness and fair for joint inflammation (kappa = 0.513, 0.448, and 0.402, respectively).	20084443
Inflammation	Altered Intercellular Communication	The sensitivity and specificity of clinical examination for joint inflammation were 0.12 and 0.95, respectively.	20084443
Degenerative polyarthritis, Inflammation, Sore to touch, Swelling	Altered Intercellular Communication	Clinical joint counts for bony swelling, tenderness, and inflammation all correlated with functional status, assessed by the functional index for hand osteoarthritis (FIHOA), whereas US joint counts for joint inflammation did not correlate with the FIHOA.	20084443
Inflammation	Altered Intercellular Communication	US detects more joints with inflammation than clinical examination in patients with EOA.	20084443
Inflammation, Damage, BDI - Functional Impairment	Altered Intercellular Communication	US can supplement the clinical examination of patients with EOA, as US-detected subclinical joint inflammation might accelerate joint damage and thus functional impairment.	20084443
Hepatocellular, Inflammation	Altered Intercellular Communication	These results suggest that intracellular Glycer-AGEs play important roles in promoting inflammation and hepatocellular death.	20084527
Inflammation, Abnormal Epithelial Cell	Altered Intercellular Communication	Thirty sets of initial, adult endoscopic biopsies suspected to be CD with subsequent resections, repeat biopsies with long-term follow-up, and/or other confirmatory laboratory results were analysed by three gastrointestinal pathologists, blinded for the final diagnosis for mucosal architectural changes, epithelial abnormalities, chronic and active inflammation and changes of muscularis mucosae and submucosa.	20085514
Inflammation, IIeocolitis, Abnormal Epithelial Cell	Altered Intercellular Communication	The majority of initial biopsies (96%) of CD were abnormal with active chronic ileocolitis with a very high proportion (80%) showing the classic combination of abnormal mucosal architecture, epithelial abnormalities and active chronic inflammation.	20085514
Inflammation	Altered Intercellular Communication	The most sensitive feature was lamina proprial chronic inflammation (sensitivity 92.7%).	20085514
Inflammation, Plasmacytosis, Abnormal Epithelial Cell	Altered Intercellular Communication	Sensitivity for other features was as follows: active inflammation 87.8%, basal plasmacytosis 82.1%, architectural changes 80.5% and epithelial abnormalities 70.7%.	20085514
Muscle damage, Myalgia, Inflammation	Altered Intercellular Communication	Branched-chain amino acid supplementation attenuates muscle soreness, muscle damage and inflammation during an intensive training program.	20087302
Muscle damage, Myalgia, Inflammation, Fatigue	Altered Intercellular Communication	These results demonstrate that BCAA supplementation during an intensive training program effectively reduces the muscle soreness and fatigue sensation, and that the perceived changes could be attributed to the attenuation of muscle damage and inflammation.	20087302
Inflammation, Carcinoma of lung	Altered Intercellular Communication	SAA levels were predictive of an elevated risk of lung cancer, supporting the general view that inflammation is implicated in lung cancer development.	20087959
Inflammation, Abscess, Lymphangitis, Edema	Altered Intercellular Communication	Paraffin oil has destructive consequences: skin inflammation, hard oedema, sterile abscesses, diffuse lymphangitis and paraffinomas.	20089216
prostatitis	Altered Intercellular Communication	Prostate inflammation can lead to an increase in serum prostate specific antigen concentration and confound the use of prostate specific antigen kinetics.	20089269
Inflammation	Altered Intercellular Communication	Only vacA s1 was significantly associated with more severe inflammation (P=0.02).	20090217
Eosinophilic granulomatosis with polyangiitis, Orbital Pseudotumor	Altered Intercellular Communication	Diffuse bilateral orbital inflammation in Churg- Strauss syndrome.	20090494
Inflammation, Eosinophilic granulomatosis with polyangiitis	Altered Intercellular Communication	A diagnosis of diffuse bilateral inflammation in Churg-Strauss syndrome was made and the patient responded dramatically to prednisolone with resolution of systemic and orbital findings.	20090494
Eosinophilic disorder, Granulomatous inflammation, Eosinophilic inflammation, orbit (eye disorders), Vasculitis, CTCAE	Altered Intercellular Communication	Three years later she developed rapidly worsening orbital disease, marked peripheral eosinophilia, and orbital biopsy showed evidence of granulomatous inflammation with marked eosinophil infiltration and vasculitic changes, and a weakly positive antineutrophil cytoplasmic autoantibody.	20090494
Eosinophilic disorder, Asthma, Eosinophilic granulomatosis with polyangiitis, Orbital Pseudotumor	Altered Intercellular Communication	Hence, diffuse bilateral orbital inflammation occurring in the setting of asthma and peripheral eosinophilia should raise the possibility of Churg-Strauss syndrome and warrants biopsy as early institution of therapy can reduce both systemic and ophthalmic complications.	20090494
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Our 2 patients presented with the typical clinical findings of small papular lesions in which histopathologic examinations disclosed granulomatous inflammation with necrosis associated with inflamed hair follicles.	20090495
Inflammation, Infection, peripheral blood, Cerebral Ischemia	Altered Intercellular Communication	Only recently it became evident that cerebral ischemia not only leads to brain tissue damage and subsequent local inflammation but also to a dramatic loss of peripheral blood T-cells with subsequent infections.	20090932
Inflammation	Altered Intercellular Communication	Perivascular carotid inflammation: an unusual case of carotidynia.	20091034
Inflammation, Thrombosis, Aneurysm	Altered Intercellular Communication	A CT scan of the neck without intravenous contrast showed perivascular inflammation of the left common carotid artery, without evidence of a collection, arterial thrombosis, aneurysm, or dissection.	20091034
Myocarditis	Altered Intercellular Communication	Based on the inflammatory index, myocardial inflammation was classified into four grades.	20091145
Inflammation, Malnutrition	Altered Intercellular Communication	When markers of inflammation or malnutrition were adjusted for separately, the association between dK and mortality was attenuated but remained significant.	20091484
Cessation of life, Inflammation, Malnutrition	Altered Intercellular Communication	After simultaneous adjustment for markers of inflammation and malnutrition, the risk of death associated with the higher dK categories was attenuated, and the overall trend was eliminated.	20091484
Cessation of life, Inflammation, Malnutrition	Altered Intercellular Communication	Although unadjusted and partially adjusted models suggested a graded association between higher dK and the risk of all-cause death, this association was apparently due to confounding by factors suggesting malnutrition and inflammation.	20091484
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Impact of adopting low sodium diet on biomarkers of inflammation and coagulation: a randomised controlled trial.	20091486
Inflammation, Vascular Diseases	Altered Intercellular Communication	Epidemiological data suggest that dietary sodium intake may be associated with systemic inflammation: another potential pathophysiological mechanism by which sodium intake may modify vascular disease.	20091486
Refractory anemias, Rheumatoid Arthritis, Arthritis, Malignant Neoplasms	Altered Intercellular Communication	Rheumatoid arthritis (RA) is characterized by an uncontrolled spread of destructive joint inflammation resembling malignancy.	20092399
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Epidemiological studies have established strong correlation between inflammation and predisposition for cancer.	20092399
Ocular surface disease, Conjunctivitis, Schirmer Tear Test Strips	Altered Intercellular Communication	Outcome measures were intraocular pressure, success rate, bleb appearance, ocular surface disease index, Schirmer's tear test 1 and conjunctival inflammation.	20092592
Inflammation	Altered Intercellular Communication	Is inflammation prior to renal transplantation predictive for cardiovascular and renal outcomes?	20092820
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Markers of non-specific inflammation, such as C-reactive protein (CRP) or leukocyte count are increased in end-stage renal disease patients.	20092820
Inflammation	Altered Intercellular Communication	Its existence in neutrophils and the enzymatic activity against phospholipids imply a role in the defence against invading microorganisms and in the generation of lipid mediators of inflammation.	20093120
Inflammation, Drug toxicity, Injury of kidney	Altered Intercellular Communication	Possible mechanisms include chronic immune rejection, inflammation, drug toxicity, and chronic kidney injury from secondary factors.	20093355
Communicable Diseases, Inflammation	Altered Intercellular Communication	This occurred despite the in situ cilium, which did not act as a nidus for infection or inflammation.	20093939
vascular inflammations	Altered Intercellular Communication	The CC genotype of the CYP11B2 C-344T polymorphism was associated with an age-dependent increase in the serum CRP level independent of BP, and may contribute to a cardiovascular phenotype by promoting vascular inflammation.	20094057
Stomatitis, Communicable Diseases, Helicobacter pylori, Gastritis	Altered Intercellular Communication	Gastritis, an inflammation of gastric mucosa, may be due to many pathological factors and infection, such as with Helicobacter pylori.	20094782
CD55 gene, Heart, In-Stent Restenosis Indicator	Altered Intercellular Communication	Inflammation state before and after PCI are the risk factors for in-stent restenosis, while the levels of TC, LDL-C and non-HDL-C are the important risk factors for other coronary lesion progression.	20095335
Inflammation, Atheroma	Altered Intercellular Communication	Statins produce hipolipemic and pleotropic effects on markers of inflammation with stabilization of atheromatous plaque.	20095516
Primary malignant neoplasm	Altered Intercellular Communication	More studies are needed to understand the role of this CR-mediated reduction in sex hormones in modulating the pathogenesis of age-associated chronic diseases such as cancer and the aging process itself.	20096034
Inflammation, Atherosclerosis, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Periodontal inflammation has been implicated in atherosclerosis and coronary heart disease (CHD).	20096894
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Because inflammation is involved in the pathogenesis of osteoarthritis (OA), we have analyzed the expression and production of HLA-G molecules in in vitro cultured synovial fibroblasts (SFs) from OA patients and control subjects.	20097242
Degenerative polyarthritis, Inflammation, Synovial joint structure	Altered Intercellular Communication	The production of HLA-G1 molecules, constitutively expressed by control and OA SFs, is significantly increased in OA, suggesting a possible mechanism to counteract the inflammation of the synovial joints.	20097242
ARCN1 gene	Altered Intercellular Communication	Measuring exhaled NO at multiple flow rates however, allows to dissect exhaled NO in an alveolar (CAlv,NO) and bronchial (J'aw,NO) fraction, which are claimed to better reflect the bronchial and alveolar inflammation in COPD.	20097553
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	Inflammation and the incidence of type 2 diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA).	20097779
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Many studies have documented associations between inflammation and type 2 diabetes incidence.	20097779
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Higher levels of inflammation predict short-term incidence of type 2 diabetes in a multiethnic American sample.	20097779
Inflammation, hearing impairment, Hyperglycemia, Diabetes Mellitus, Neuralgia	Altered Intercellular Communication	Mechanisms related to neuropathic or microvascular factors, inflammation, or hyperglycemia may be mediating the association of diabetes and hearing impairment.	20097782
Inflammation	Altered Intercellular Communication	Salzmann nodular degeneration is a disease of uncertain etiology in which inflammation of the ocular surface may play a role.	20098304
No ocular symptoms, conjunctiva, Conjunctivitis, Structure of corneal epithelium	Altered Intercellular Communication	ProKera was inserted in both eyes at day 10 after onset of ocular symptoms in a 5-year-old boy suffering from acute TEN, manifesting conjunctival inflammation, large conjunctival defects, pseudomembrane formation, and total corneal epithelial defects.	20098313
Conjunctivitis	Altered Intercellular Communication	However, because ProKera only covered the cornea and perilimbal conjunctiva, these 2 eyes still showed some conjunctival inflammation several months after discharge from the hospital.	20098313
Inflammation, "Alzheimers Disease", Cell body of neuron, Data types - Address	Altered Intercellular Communication	Inflammation, insoluble protein deposition and neuronal cell loss are important features in the Alzheimer's disease (AD) brain.	20098622
Inflammation	Altered Intercellular Communication	These results suggest that S100a9 induced by Abeta or CT contributes to cause inflammation, which then affects the neuropathology including amyloid plaques burden and impairs cognitive function.	20098622
Inflammatory abnormality of the eye	Altered Intercellular Communication	At the moment of evaluation, ocular inflammation was quiescent in all the patients.	20099233
Leucocytic infiltrate, Corneal Neovascularization, Inflammatory abnormality of the eye	Altered Intercellular Communication	The absence of inflammatory cell infiltration may be explained by the prolonged control of ocular inflammation in our patients, which may also have limited stimuli for corneal neovascularization.	20099233
Intraocular inflammation	Altered Intercellular Communication	After 1 week of steroids, visual acuity and intraocular inflammation improved significantly.	20099238
Giant Cell Arteritis, Arteritis	Altered Intercellular Communication	Diagnostic value of T2-weighted imaging for the detection of superficial cranial artery inflammation in giant cell arteritis.	20099359
Inflammation, Lobular Endocervical Glandular Hyperplasia	Altered Intercellular Communication	Possible relationship between chronic inflammation and pyloric metaplasia in a patient with lobular endocervical glandular hyperplasia.	20099512
Inflammation, Hyperplasia	Altered Intercellular Communication	The histological findings, in relation to the previous cesarean section suggest that the ectopic pyloric hyperplasia in the present case could represent a heteroplastic or metaplastic process due to a multidirectional differentiation of cervical glands during chronic inflammation by foreign bodies.	20099512
Chronic abdominal pain, Weight decreased, Fever, CTCAE, Inflammation	Altered Intercellular Communication	She was hospitalized due to fever with deterioration of her general condition (more than 10% of body weight loss) and chronic abdominal pain with inflammation.	20099679
Schizophrenia	Altered Intercellular Communication	Cortical GABA deficits that are consistently reported in schizophrenia may reflect an etiology of failed normal postnatal neurotransmitter maturation.	20100621
palladium, Inflammation	Altered Intercellular Communication	The change in PSTR during the first year of PD is related to PDE IL-6 AR, which may represent intraperitoneal inflammation; however, there does not seem to be a close association between PSTR and the degree of systemic inflammation.	20100731
Inflammation	Altered Intercellular Communication	These results suggest that income explains the association between education and peripheral inflammation.	20100883
Inflammation	Altered Intercellular Communication	In short, the reason that higher education is linked to reduced peripheral inflammation is because it reduces the risk for low income status, which is what is directly associated with reduced peripheral inflammation.	20100883
Optimism, Inflammation, Atherosclerosis	Altered Intercellular Communication	Association of optimism and pessimism with inflammation and hemostasis in the Multi-Ethnic Study of Atherosclerosis (MESA).	20100888
Inflammation, Refractory anemias, Chronic Obstructive Airway Disease, Chronic inflammatory disorder, Asthma, Depressed mood	Altered Intercellular Communication	Although histone deacetylase (HDAC) inhibitors (HDACis) demonstrate therapeutic effects in animal models of chronic inflammatory disease, depressed macrophage HDAC activity in patients with asthma, chronic obstructive pulmonary disease, or RA may contribute to inflammation in these diseases, potentially contraindicating the therapeutic administration of HDACis.	20100935
Refractory anemias, Inflammation	Altered Intercellular Communication	Our study identifies redundant, but essential, roles for class I/II and sirtuin HDACs in promoting inflammation, angiogenesis, and cell survival in RA.	20100935
ovarian neoplasm, Inflammation	Altered Intercellular Communication	An extensive multiple-pathway assessment found evidence that inherited differences may play a role in outcome of ovarian cancer patients, particularly in genes within the angiogenesis and inflammation pathways.	20103664
Inflammation, Disorder of skeletal muscle, Heart failure	Altered Intercellular Communication	Low 25-hydroxyvitamin D levels, commonly found in older patients with heart failure, may contribute to the chronic inflammation and skeletal myopathy that lead to poor exercise tolerance.	20103775
Inflammation, Pseudotumor, Neoplasms	Altered Intercellular Communication	An inflammatory pseudotumor of the spleen is a rare benign tumor and designated as mass-like lesions with histologic features of nonspecific inflammation and mesenchymal repair although its etiopathogenesis still remains unknown.	20103878
Inflammation, Primary malignant neoplasm, Cocaine-Related Disorders, Atherosclerosis, Diabetes Mellitus	Altered Intercellular Communication	Since recent investigations have suggested that inflammation possibly contributes to the pathogenesis of age-related disorders including atherosclerosis, cancer, and diabetes mellitus, the term "inflammaging," a combination of "inflammation" and "aging," has been coined.	20103915
Williams Syndrome	Altered Intercellular Communication	WS may be a good model for analyzing inflammaging.	20103915
Inflammation, Primary malignant neoplasm, Cocaine-Related Disorders, Atherosclerosis, Diabetes Mellitus	Altered Intercellular Communication	Since recent investigations have suggested that inflammation possibly contributes to the pathogenesis of age-related disorders including atherosclerosis, cancer, and diabetes mellitus, the term "inflammaging," a combination of "inflammation" and "aging," has been coined.	20103915
Inflammation, Williams Syndrome	Altered Intercellular Communication	Sera from 14 mutation-proven WS patients (ages: 33-70 years) and 21 healthy Japanese adults ages 15 to 95 years were examined with ELISA for soluble Fas ligand (sFasL) to compare conventional inflammation markers.	20103915
Inflammation, Williams Syndrome	Altered Intercellular Communication	In conclusion, an increased level of serum sFasL in natural aging and WS patients may suggest a common pathophysiological mechanism: inflammation.	20103915
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Though difficult, differentiating the occurrence of malignant tumors from worsening chronic inflammation is crucial.	20103937
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Upregulation of monocyte tissue factor activity is significantly associated with low-grade chronic inflammation and insulin resistance in patients with metabolic syndrome.	20103969
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	The metabolic syndrome (MetS) is a cluster of cardiovascular risk factors closely linked to inflammation and insulin resistance (IR).	20103969
Inflammation, Tissue Factor	Altered Intercellular Communication	Upregulation of monocyte TF is significantly associated with low-grade inflammation and IR in MetS.	20103969
Inflammation, Fatty degeneration	Altered Intercellular Communication	Both forms of CK18 significantly correlated with degree of steatosis, lobular inflammation, and ballooning, and showed stronger positive correlations with NAS than serum aspartate and alanine aminotransferase (AST and ALT).	20104187
Inflammation	Altered Intercellular Communication	Plasma MIC-1 correlates with systemic inflammation but is not an independent determinant of nutritional status or survival in oesophago-gastric cancer.	20104227
Inflammation	Altered Intercellular Communication	Macrophage inhibitory cytokine-1(MIC-1) is a potential modulator of systemic inflammation and nutritional depletion, both of which are adverse prognostic factors in oesophago-gastric cancer (OGC).	20104227
Inflammation, Fibrosis Assessment, Hepatitis B	Altered Intercellular Communication	Forty-eight (30.8%) and 39 (25.0%) patients of non-mild chronic hepatitis B were found to have G3-4 inflammation and S3-4 fibrosis, respectively.	20104760
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Hostile individuals with advanced cardiovascular disease may be particularly susceptible to stress-induced increases in sympathetic activity and inflammation.	20105692
Allergic, Inflammation, Granuloma, Suppuration, Fibrosis Assessment, Granulomatous, Infarction	Altered Intercellular Communication	As per the results, the characteristic histological features were allergic mucin in allergic, fungal ball in chronic non-invasive, sparse inflammation and numerous hyphae in chronic invasive, non caseating granulomas with dense fibrosis in granulomatous invasive, and infarction with suppuration in acute fulminant FRS.	20107998
Refractory anemias, Inflammation, Paresis	Altered Intercellular Communication	Initiation of rituximab for continuing synovial inflammation led to remission of RA, but no amelioration of muscle weakness was noted.	20108015
Inflammation	Altered Intercellular Communication	However, the functional outcome was poor because of persistant inflammation of the anterior segment.	20108572
Pneumonitis	Altered Intercellular Communication	When inhaling medication, it is essential that drug particles are delivered to all sites of lung inflammation, including the peripheral airways.	20109122
Inflammation	Altered Intercellular Communication	Elevated levels of the BCA-1 and SDF-1alpha and their receptors may account for an increased presence of B cells and their products, contributing to eosinophilic inflammation in patients with CRSwNP.	20109310
Inflammation, Hemorrhage, Perforation (observation), Intestinal Obstruction	Altered Intercellular Communication	MD may give rise to bleeding, intestinal obstruction and inflammation; however its perforation by a foreign body is an extremely rare life-threatening complication.	20109374
Functional Disability, Myositis	Altered Intercellular Communication	In order to prevent severe complications and functional disabilities, early aggressive treatments should be considered when muscle inflammation is refractory to ordinary treatment.	20110203
Inflammation, Atherosclerosis, Coronary heart disease	Altered Intercellular Communication	Markers of atherosclerosis and inflammation for prediction of coronary heart disease in older adults.	20110287
Inflammation, Hyperparathyroidism	Altered Intercellular Communication	Iron, inflammation, dialysis adequacy, nutritional status, and hyperparathyroidism modify erythropoietic response.	20110344
Inflammation, Data types - Address	Altered Intercellular Communication	Overall, these findings show that AD-linked dysregulated immune mechanisms exist, which lead to dendritic cell-mediated over-activation of inflammation and impaired antigen presentation, thus supporting the view that immune cell activation could play an important role in AD pathogenesis.	20110602
Hyperglycemia, Inflammation, Necrosis	Altered Intercellular Communication	Hyperglycaemia at admission was associated with worse cardiovascular risk profile, high levels of necrosis and inflammation biomarkers and low left ventricle ejection fraction.	20110816
Inflammation	Altered Intercellular Communication	Adipocypte fatty acid-binding protein-4 (FABP4/adipocyte P2) may play a central role in energy metabolism and inflammation.	20111020
Migraine Disorders, Inflammation	Altered Intercellular Communication	Cytokine polymorphism in patients with migraine: some suggestive clues of migraine and inflammation.	20113413
Pain Distress Question, Inflammation, Neuropathy	Altered Intercellular Communication	Transient receptor potential vanilloid 2 (TRPV2), one of the members of TRP (transient receptor potential) superfamily of ion channels, has been suggested to contribute to pain associated with inflammation or neuropathy.	20113837
Inflammation, Hypoxia, Comorbidity, Alteration in nutrition	Altered Intercellular Communication	Notable among these factors are systemic inflammation, nutritional alterations, the use of certain drugs, hypoxia and the presence of comorbidity and/or advanced age.	20116748
Intraocular inflammation	Altered Intercellular Communication	Four weeks after surgery, visual acuity was restored and there were no signs of intraocular inflammation.	20117721
Communicable Diseases, Prototheca, Inflammation	Altered Intercellular Communication	Prototheca spp can be considered as saprophytes, and in spite of their frequency in the environment, they are of low virulence and may cause chronic infection with low-grade inflammation in humans.	20117953
Anxiety, CTCAE 3.0, Asthma	Altered Intercellular Communication	A sample of 195 patients, mostly middle-aged women with moderate/severe asthma, underwent pulmonary function and airway-inflammation tests and were given anxiety rating questionnaires.	20118439
Airway structure, Anxiety, CTCAE 3.0	Altered Intercellular Communication	Anxiety was associated with worse subjective asthma outcomes and increased use of medication/healthcare services, but with decreased airway inflammation, and was not associated with lung function.	20118439
Intraocular inflammation, Fungal endophthalmitis, Decreased translucency, Candida parapsilosis	Altered Intercellular Communication	Early postoperatively, she developed intrastromal opacities, which were thought to be epithelial downgrowth, but progression and increasing stromal and intraocular inflammation required anterior chamber and vitreous tap, which confirmed the presence of Candida parapsilosis, confirming the diagnosis of fungal endophthalmitis.	20118788
Intraocular Infection, Inflammation	Altered Intercellular Communication	Corneal venting incisions in DSAEK surgery may be a portal of entry for microorganisms, leading to corneal and intraocular infection, and a high index of suspicion is warranted in the presence of stromal infiltrates or inflammation at venting sites.	20118788
Hepatic inflammation	Altered Intercellular Communication	No significant association was found between CTGF level and the grade of hepatic inflammation (p > 0.05).	20121404
Inflammation, Interstitial Fibrosis Assessment, Tubular atrophy	Altered Intercellular Communication	Impact of subclinical inflammation on the development of interstitial fibrosis and tubular atrophy in kidney transplant recipients.	20121731
Interstitial inflammation	Altered Intercellular Communication	The percent with IF/TA score > 2 and interstitial inflammation (Banff i score > 0) was higher in group 2 (16%, p = 0.004) and group 3 (37%, p < 0.0001) compared to group 1 (3%).	20121731
Chronic inflammation, Atherosclerosis, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	Chronic inflammations, atherosclerosis and obesity, are major risk factors for cardiovascular diseases.	20122177
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	We hypothesized that exposure to PM causes prothrombotic changes in persons with diabetes, possibly via systemic inflammation.	20123602
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Traffic exposure may increase cardiovascular disease (CVD) risk via systemic inflammation and elevated blood pressure, two important clinical markers for managing disease progression.	20123638
Inflammation	Altered Intercellular Communication	Significantly suppressing inflammation with the immunosuppressive drug cyclosporin A did not affect colonization by HP but blocked the induction of altered DNA methylation.	20124475
Inflammation, Atherosclerosis	Altered Intercellular Communication	In view of discrete associations with cytokines, FMD, beta-blockers and statins, mDCs and pDCs seem to behave differently and may influence inflammation during atherosclerosis in different ways.	20124992
Refractory anemias, Inflammation, palladium	Altered Intercellular Communication	The relationship between RA and PD disease activities is not clear, but the importance of periodontal treatment in the control of inflammation to avoid tooth extraction is evident.	20126902
Carcinogenesis, Gastritis	Altered Intercellular Communication	IL-17A, -17F and MIF have a crucial role in the gastric inflammation and carcinogenesis.	20127054
Carcinogenesis	Altered Intercellular Communication	Polyamines are important in cell growth and wound repair, but have also been implicated in inflammation-induced carcinogenesis.	20127992
Inflammation, Hypersensitivity, IL13 gene	Altered Intercellular Communication	Allergic rhinitis, a disease that impairs quality of life, is characterized by inflammation due to an allergic reaction.	20128420
Granuloma, Inflammation, Uveomeningoencephalitic Syndrome	Altered Intercellular Communication	Subretinal granulomatous lesion may present a manifestation of VKH and mean long standing subretinal fluid and inflammation.	20128649
Inflammation, S100A4 protein, human	Altered Intercellular Communication	The main concern with benign lesions presenting with inflammation is malignant transformation; thus, clinicians need to be more aware of Meyerson phenomenon.	20128988
Inflammation, Data types - Address	Altered Intercellular Communication	Functionally, this signature highlights genes involved in pathways that were associated with macrophages and lymphocytes within AD patients: Transforming growth factor (TGF-beta) signaling, oxidative stress, innate immunity and inflammation, cholesterol homeostasis, and lipid-raft perturbation, whereas other genes may also provide new insights in the biology of AD.	20129318
Inflammation, Intramyometrial route	Altered Intercellular Communication	Pathologic diagnosis confirmed an intramyometrial abscess, originating from the wall of the uterus occupying the entire uterine cavity, lined with granulation tissue, foamy macrophages, and chronic inflammation.	20129341
Inflammation, Pain Distress Question	Altered Intercellular Communication	Glial cell line-derived neurotrophic factor (GDNF) is involved in inflammation and pain, roles which remain to be delineated clinically.	20129677
Inflammation, Extravasation	Altered Intercellular Communication	Age-related macular degeneration is a multifactorial disease involving inflammation, neovascularization, and vascular leakage.	20130708
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Galectin-3 is a recently developed biomarker associated with fibrosis and inflammation, and it may play a role in cardiac remodeling in HF.	20130888
Sepsis, Inflammation, Septic Shock	Altered Intercellular Communication	PCT results were classed as: 0.5 ng/ml = sepsis unlikely; >or=0.5 to <2 = sepsis possible; >or=2 to <10 = systemic inflammation; >or=10 = septic shock.	20131075
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	Increased expression of interleukin-7 in labial salivary glands of patients with primary Sjogren's syndrome correlates with increased inflammation.	20131250
Inflammation	Altered Intercellular Communication	To characterize the cellular architecture of the tophus and to determine the presence of cytokines implicated in the initiation and resolution of gouty inflammation.	20131281
Inflammation	Altered Intercellular Communication	The coexpression of IL-1beta and TGFbeta1 suggests that both proinflammatory and antiinflammatory factors present within the tophus contribute to a cycle of chronic inflammation, attempted resolution, and tissue remodeling.	20131281
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Expression of Notch homologues in local tissue inflammation in rheumatoid arthritis (RA) and cultured synoviocytes has been reported, but the expression profile of Notch-related molecules in peripheral lymphocytes in RA remains unclear.	20132067
Inflammation	Altered Intercellular Communication	Exercise in systemic sclerosis intensifies systemic inflammation and oxidative stress.	20132073
Inflammation	Altered Intercellular Communication	Basal and exercise-induced inflammation and oxidative stress were correlated with the modified Rodnan skin score.	20132073
Sample Size Calculation, Inflammation	Altered Intercellular Communication	Although exercise capacity is impaired in patients with SSc, physical activity intensifies the already increased basal levels of systemic inflammation and oxidative stress.	20132073
Inflammation, Sample Size Calculation	Altered Intercellular Communication	These data support the concept of a role for systemic inflammation and oxidative stress in the ongoing systemic effects of SSc.	20132073
Inflammation, SERPINB3 wt Allele	Altered Intercellular Communication	It is therefore plausible that functional variants in DNA repair genes and/or genes controlling inflammation and immunological response play a role in determining susceptibility to OSCC.	20133197
Pain Distress Question, Viral pericarditis, Idiopathic recurrent pericarditis, Myocarditis	Altered Intercellular Communication	Treatment for idiopathic pericarditis and viral pericarditis, which account for about 85% of cases, focuses on pain management and decreasing pericardial inflammation.	20133530
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	The CD40/CD40L interaction activates various pathways in immune and nonimmune cells related to inflammation and was shown to be critical for the development of IBD.	20133813
Carcinogenesis	Altered Intercellular Communication	Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks.	20133864
Primary malignant neoplasm, Liver carcinoma, Hepatitis, Chronic, FAM126A gene	Altered Intercellular Communication	Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality worldwide and is considered to be the outcome of chronic liver inflammation.	20133864
Inflammation, Neoplastic Cell Transformation	Altered Intercellular Communication	Our aim was to understand the molecular mechanisms linking liver regeneration under chronic inflammation to hepatic tumorigenesis.	20133864
Primary malignant neoplasm, Hepatocarcinogenesis	Altered Intercellular Communication	Mdr2-KO mice, a model of inflammation-associated cancer, underwent partial hepatectomy (PHx), which led to enhanced hepatocarcinogenesis.	20133864
Inflammatory abnormality of the eye	Altered Intercellular Communication	Adverse events potentially related to dacetuzumab included cytokine release syndrome symptoms, non-infectious ocular inflammation, and elevated hepatic enzymes.	20133895
Inflammation, hepcidin	Altered Intercellular Communication	Concentrations of hemoglobin, serum hepcidin and parameters of iron status and inflammation were determined at baseline and 4 weeks after antimalarial treatment.	20133896
Communicable Diseases	Altered Intercellular Communication	Malnutrition-inflammation score independently determined cardiovascular and infection risk in peritoneal dialysis patients.	20134162
Increased insulin level, Inflammation, Dyslipidemias, Diabetes Mellitus, Hypertension, CTCAE	Altered Intercellular Communication	However, when adjustments were made for the presence of diabetes, dyslipidemia, hypertension, hyperinsulinemia, and inflammation, WHR was no longer significantly (P>0.41) associated with incident CVD.	20134327
Communicable Diseases, Inflammation	Altered Intercellular Communication	Therefore, it can be used for the differential diagnosis of the infection, especially in cases of serious inflammation.	20134373
Inflammation, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	These were lobular inflammation, portal inflammation, interface hepatitis, and fibrosis.	20134396
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	High plasma phospholipase A2 activity, inflammation markers, and LDL alterations in obesity with or without type 2 diabetes.	20134414
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	[Cytokine and acute phase inflammation reactant levels in men with myocardial infarction].	20135880
Fibrosis Assessment, Malnutrition, Pneumonitis	Altered Intercellular Communication	Cystic fibrosis (CF) is characterized by malnutrition, chronic pulmonary inflammation, and oxidative stress.	20136439
Granuloma Annulare	Altered Intercellular Communication	Granuloma annulare (GA) is a rare disease characterized by granulomatous inflammation of the dermis.	20136918
Neurogenic Inflammation	Altered Intercellular Communication	Reports on those proximal connections can therefore obviously not extend to mechanoinsensitive C-fibres and do not explain the origin of neurogenic inflammation in humans without prior sensitization.	20138429
Pneumonitis	Altered Intercellular Communication	Measurement of biomarkers in exhaled breath condensate (EBC) may be useful for monitoring lung inflammation and injury in mechanically ventilated patients.	20138493
Inflammation, Disease	Altered Intercellular Communication	Subjects with socket inflammation, contracted sockets, or other known lid disorders were excluded.	20138606
Diabetic Nephropathy, Inflammation, Atherosclerosis, diabetic	Altered Intercellular Communication	Our results suggest that low-grade inflammation, microinflammation, may be a common risk factor for diabetic nephropathy and atherosclerosis in Japanese type 2 diabetic patients.	20138680
Diffuse Large B-Cell Lymphoma, Chronic inflammation	Altered Intercellular Communication	On the basis of 2008 World Health Organization diagnostic criteria, we believe these cases should be classified as DLBCL associated with chronic inflammation.	20139760
Diffuse Large B-Cell Lymphoma, Chronic inflammation	Altered Intercellular Communication	However, unlike the characteristically poor prognosis reported in this entity, we hypothesize that the disease resectability in these cardiac sites, in many cases, may allow for a better prognosis than DLBCL with chronic inflammation at other less resectable sites.	20139760
Communicable Diseases, Inflammation, Neoplasms	Altered Intercellular Communication	PET/CT demonstrated suspected pathologic foci of Fluorine-18 fluorodeoxyglucose (F-18 FDG) uptake in 41 patients (60%), in 38 of these 41 patients (93%) F-18 FDG PET/CT helped in identifying the causal source, including infection in 25 patients, inflammation in 11 patients, a benign neoplasm in 1 patient, and in 1 patient rejection of a pancreas transplant.	20139818
Degenerative disorder, Traumatic injury	Altered Intercellular Communication	As much as 17 patients suffered from trauma, 5 of degenerative disease, 3 of inflammations and 2 of metastatic disease.	20140465
Squamous cell carcinoma	Altered Intercellular Communication	[Syndrome of inappropriate secretion of antidiuretic hormone associated with resection of pulmonary squamous cell carcinoma].	20141082
DiGeorge Syndrome, Inflammatory abnormality of the eye, Uveitis, 22q11.2	Altered Intercellular Communication	Uveitis in DiGeorge syndrome: a case of autoimmune ocular inflammation in a patient with deletion 22q11.2.	20141355
Inflammation	Altered Intercellular Communication	Urokinase receptor (urokinase-type plasminogen activator receptor [uPAR], CD87), a GPI-anchored protein, is considered to play an important role in inflammation and fibrinolysis.	20142364
Pneumonitis	Altered Intercellular Communication	uPAR-deficient mice intranasally infected with B. pseudomallei showed an enhanced growth and dissemination of B. pseudomallei when compared with wild-type mice, corresponding with increased pulmonary and hepatic inflammation.	20142364
Inflammation, Prostate carcinoma, Benign prostatic hypertrophy	Altered Intercellular Communication	Biomarkers of systemic inflammation and risk of incident, symptomatic benign prostatic hyperplasia: results from the prostate cancer prevention trial.	20142396
Inflammation	Altered Intercellular Communication	Results suggest that systemic inflammation or lower levels of soluble receptors that bind inflammatory cytokines increase BPH risk.	20142396
Restless Legs Syndrome	Altered Intercellular Communication	Selective serotonin reuptake inhibitors have been associated with the risk of restless legs syndrome (RLS), suggesting that dysregulation of serotonergic neurotransmission may provoke or exacerbate RLS.	20142619
Inflammation	Altered Intercellular Communication	Moreover, secondary inflammation may be identified in PanCa, further complicating diagnosis.	20143430
Inflammation, Hepatitis B, Liver Cirrhosis	Altered Intercellular Communication	Group I had distinct features compared with group II, including a low frequency of hepatolithiasis (P = 0.000); a high positive rate of serum hepatitis B surface antigen (P = 0.000) and hepatitis B virus (HBV)-associated cirrhosis (P = 0.038); a high frequency of alpha-fetoprotein (> 400 microg/L) (P = 0.011); a low frequency of carbohydrate antigen 19-9 (> 37 U/mL) (P = 0.017); and a high frequency of liver histological inflammation (P = 0.002).	20143468
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	We sought to assess weather inflammation is involved in the impaired vascular reactivity induced by ADMA in essential hypertension.	20144072
Inflammation, Blood Vessel	Altered Intercellular Communication	Probably, the chronic inflammation documented in these patients may be considered the mechanistic link between ADMA and vascular damage.	20144072
ARCN1 gene, Reduced Device Function, Bronchiectasis, Airway structure, Mucus retention, Exacerbation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Persistent airway inflammation with mucus retention in patients with chronic airway disorders such as COPD and bronchiectasis may lead to frequent exacerbations, reduced lung function and poor quality of life.	20144858
Deoxyglucose, vascular inflammations, atherosclerotic	Altered Intercellular Communication	Metabolic assessment of vascular inflammation by 2-[F]fluoro-2-deoxy-D-glucose positron emission tomography (FDG)-PET is a promising new approach for the evaluation of the vulnerability of atherosclerotic plaques.	20145577
Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Reports were assessed for significant abnormal findings, including malignancy, infectious processes, and chronic inflammation.	20145929
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	Hyaluronidase allergy: a rare cause of periorbital inflammation.	20148844
Hemorrhage, Allergy - Charge Type Reason, Communicable Diseases, Orbital Pseudotumor, Acute-Phase Reaction	Altered Intercellular Communication	This case shows that despite being less common than haemorrhage for acute reactions and infection for delayed reactions, allergy can account for orbital inflammation following ophthalmic surgery.	20148844
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Hypoxia inducible factor-1-alpha (HIF-1alpha) is related to both angiogenesis and inflammation in rheumatoid arthritis.	20149310
Refractory anemias, Inflammation	Altered Intercellular Communication	Despite the important role of the transcription factor HIF-1alpha in angiogenesis and inflammation, only a few studies on HIF-1alpha expression have been performed in RA patients.	20149310
Inflammation, Synovitis	Altered Intercellular Communication	The amount of inflammation was determined by counting inflammatory cells, by estimating the proliferation marker Ki67 in inflamed tissue, and by using a recently published synovitis score which gives an accurate estimate of the amount of inflammation present.	20149310
Refractory anemias, Inflammation	Altered Intercellular Communication	HIF-1alpha expression is strongest in the sub-lining layer of RA synovium and is related to both angiogenesis and inflammation in synovium from RA patients.	20149310
Refractory anemias, Inflammation	Altered Intercellular Communication	These results thus suggest that HIF-1alpha could serve as an important new therapeutic target in RA, targeting both angiogenesis and inflammation.	20149310
Inflammation, Pancreatitis, Fibrosis Assessment, Autoimmune Pancreatitis, Mass of pancreas	Altered Intercellular Communication	However, when the biopsy from a pancreatic mass shows dense chronic inflammation and fibrosis and the serum IgG4 level is not available, it presents a diagnostic dilemma whether it represents autoimmune pancreatitis or peritumoral pancreatitis.	20149413
Inflammation, Pancreatitis, Adenocarcinoma of pancreas, Autoimmune Pancreatitis, Pancreatic Ductal Adenocarcinoma	Altered Intercellular Communication	We performed IgG4 immunohistochemistry on 25 cases of autoimmune pancreatitis-lymphoplasmacytic sclerosing pancreatitis, 7 cases of autoimmune pancreatitis with granulocytic epithelial lesions, 8 cases of nonspecific pancreatitis, 15 cases of pancreatitis associated with pancreatic ductal adenocarcinoma, and 5 biopsies of pancreatic adenocarcinoma with variable inflammation.	20149413
Inflammation, Pancreatitis	Altered Intercellular Communication	IgG4-positive cells in peritumoral pancreatitis and nonspecific pancreatitis cases were closely associated with malignant glands and areas of acute inflammation in some cases.	20149413
Microalbuminuria, Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Ezetimibe ameliorated the status of metabolic syndrome and microalbuminuria, reduced inflammation and oxidative stress, and increased nitric oxide bioavailability in a LDL-chol reduction-dependent and -independent manner.	20150722
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Tissue factor (TF) is important for initiation of coagulation and for the increased thrombin activity observed at sites of inflammation.	20150920
Inflammation, Hemorrhage, Osteopenia	Altered Intercellular Communication	The following aspects of disease were assessed to describe the peri-implant condition: detectable radiographic peri-implant bone loss and inflammation, the presence of bleeding on probing at a probing depth >or=4 or >or=6 mm, and radiographic peri-implant bone loss assessed at >or=2.0 and >or=3.0 mm.	20151801
Inflammation, Osteopenia	Altered Intercellular Communication	Peri-implant inflammation was a frequent finding with and without peri-implant bone loss.	20151801
Inflammation, Periodontitis	Altered Intercellular Communication	These data support the hypothesis that elevated GCF biomarkers of inflammation and bone resorption from a small number of moderate/deep sites have the potential to identify patients who are vulnerable to progressive periodontitis, and SDD may modify that risk.	20151804
Inflammation, Inflammatory disorder, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is an inflammatory disease in which systemic inflammation correlates with disease activity.	20152234
Inflammation, Corneal edema	Altered Intercellular Communication	One day postoperatively, diffuse corneal edema and anterior chamber inflammation were evident.	20152620
Cataract, Inflammation	Altered Intercellular Communication	To compare the anti-inflammatory efficacy and subjective tolerability of preservative-free and preserved diclofenac 0.1% and preserved ketorolac 0.5% eye drops for prophylaxis and management of inflammation after cataract surgery.	20152959
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Role of inflammation and oxidative stress in atrial fibrillation.	20153266
Inflammation	Altered Intercellular Communication	Increasing evidence indicates that inflammation and oxidative stress contribute to the pathogenesis of AF, but their role remains poorly defined.	20153266
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	In addition, whether inflammation and oxidative stress are associated with particular types of AF is unclear.	20153266
Inflammation	Altered Intercellular Communication	The purpose of this study was to define the role of inflammation and oxidative stress in AF.	20153266
Inflammation	Altered Intercellular Communication	Inflammatory biomarkers were significantly increased in patients with AF, supporting a strong association between inflammation and AF.	20153266
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Galectin-3 is a carbohydrate binding protein that plays many important regulatory roles in inflammation, immunity and cancer.	20153309
Inflammation	Altered Intercellular Communication	Early onset chronic inflammation is present in CF.	20153702
Inflammation	Altered Intercellular Communication	Platelets may contribute to inflammation by cytokine release and interaction with leukocytes.	20153702
Tissue damage, Inflammation	Altered Intercellular Communication	In CF, platelet proinflammatory activity is increased at very young age already and might promote inflammation and tissue damage.	20153702
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	This endocardial inflammation correlates with vasculitis, which is the principal pathogenetic mechanism of the disease.	20154032
ARCN1 gene, Inflammation, Hypoxia	Altered Intercellular Communication	The effects of hypoxia on markers of coagulation and systemic inflammation in patients with COPD.	20154074
ARCN1 gene, Inflammation, Thrombophilia, Hypoxia, Exacerbation, vinyltriethoxysilane	Altered Intercellular Communication	Patients with COPD are also at increased risk of VTE, particularly during exacerbations, possibly because of a hypercoagulable state secondary to hypoxia and/or heightened systemic inflammation.	20154074
ARCN1 gene, Inflammation, Hypoxia	Altered Intercellular Communication	We investigated the effects of hypoxia on indices of coagulation and systemic inflammation in patients with COPD.	20154074
ARCN1 gene, Inflammation	Altered Intercellular Communication	This study demonstrates that a 2-h hypoxic challenge in patients with COPD results in coagulation activation in conjunction with an increase in systemic inflammation.	20154074
Peripheral Vascular Diseases, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Endothelial dysfunction and inflammation are understood to contribute to the onset of peripheral arterial disease (PAD), and endothelin (ET) may play an important role in this process.	20154344
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	This study investigated the role of ET in PAD, and its relationships with symptoms, endothelial dysfunction and inflammation.	20154344
Inflammation	Altered Intercellular Communication	Plasma concentrations of ET in patients with PAD are greatest in early disease; ET concentrations decrease substantially and inflammation arises as disease advances.	20154344
NDUFAB1 gene	Altered Intercellular Communication	Our data suggest that, in the elderly, inflammation-associated polymorphisms are related to atherogenesis and that the finding of ACP on US scan can be valuable in identifying subjects at risk for CV events, even if they lack traditional cardiovascular risk factors such as an increase in IMT.	20154512
Rupture, Inflammation	Altered Intercellular Communication	Although the apparent site of the rupture was not obvious, there was a wide area of acute inflammation in the mediastinal adipose tissue.	20155350
Inflammation, Anterior scleritis, Scleromalacia perforans, Necrotizing	Altered Intercellular Communication	There are three types of anterior scleritis: diffuse, nodular, and necrotizing with and without inflammation (scleromalacia perforans).	20155432
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In ulcerative colitis (UC) gut bacteria drive inflammation.	20155842
Inflammation	Altered Intercellular Communication	The results support the concept that NOD2 risk alleles contribute to impaired regulation of inflammation in the ileum.	20155851
Ovarian Cysts	Altered Intercellular Communication	This case illustrates that fetal and maternal ovarian cysts may co-exist and could potentially have a similar hormonal etiology.	20156113
Inflammation, Chronic diarrhea, Colitis	Altered Intercellular Communication	Collagenous colitis (CC) is characterized by chronic watery diarrhea, a macroscopically normal colonic mucosa but typical microscopic inflammation.	20156310
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Chronic mucosal inflammation of the colon and rectum has earlier been associated with altered visceral sensitivity, but anorectal function has never been reported in cases of CC.	20156310
Inflammation, Hypersensitivity, Colitis	Altered Intercellular Communication	Collagenous colitis was not associated with rectal hypersensitivity or disturbed anal function despite rectal inflammation.	20156310
Autoimmune Diseases	Altered Intercellular Communication	Although regulatory T lymphocytes (Tregs) have a pivotal role in preventing autoimmune diseases and limiting chronic inflammatory conditions, they may also block beneficial immune responses by preventing sterilizing immunity to certain pathogens.	20156359
Inflammation, Obesity	Altered Intercellular Communication	Both, cigarette smoking and obesity were accompanied by subclinical systemic inflammation.	20156719
Airway structure, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Relationship between airway inflammation and remodeling in patients with asthma and chronic obstructive pulmonary disease.	20156734
ARCN1 gene, Asthma, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Despite a number of important differences in the pathogenesis, course and prognosis of asthma and chronic obstructive pulmonary disease (COPD), these two entities also have common features with airway inflammation being one of them.	20156734
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Inflammation and microvascular and macrovascular endothelial dysfunction in rheumatoid arthritis: effect of treatment.	20156948
Refractory anemias, Rheumatoid Arthritis, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	To determine whether abnormalities in microvascular and macrovascular function in rheumatoid arthritis (RA) are associated with plasma markers [von Willebrand factor (VWF)] of endothelial dysfunction and inflammation [C-reactive protein (CRP)] and whether the abnormalities would be altered by treatment.	20156948
Refractory anemias, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Endothelial dysfunction and inflammation in RA may contribute to adverse cardiovascular events.	20156948
Refractory anemias, Inflammation	Altered Intercellular Communication	Patients with RA have abnormal endothelium-independent microvascular function that correlates with inflammation but is not altered by short-term antiinflammatory therapy.	20156948
Inflammation, Ichthyosis Bullosa of Siemens, Irritable Bowel Syndrome	Altered Intercellular Communication	Inflammation and immune activation have repeatedly been suggested as pathogentic factors in irritable bowel syndrome (IBS).	20158890
Renal Insufficiency, Inflammation	Altered Intercellular Communication	GDF-15 was consistently related to cardiovascular risk factors and biochemical markers of hemodynamic stress, renal dysfunction, and inflammation.	20160200
Retinitis Pigmentosa, Neoplasms	Altered Intercellular Communication	Inflammation within index tumors of 236 men undergoing RP from 1996 to 2004 was graded by a single pathologist as grade 0 (absent), 1 (mild: < or =10%), and 2 (marked: >10%).	20160265
Post-infectious disorder, Dyspepsia, Gastritis	Altered Intercellular Communication	The histological score of chronic gastric inflammation was greater in post-infectious functional dyspepsia versus patients with nonspecific functional dyspepsia or healthy controls.	20163288
Arthritis, Urticaria	Altered Intercellular Communication	We present a 6 year old boy with chronic urticaria of neonatal onset associated in childhood with features of neurological and joint inflammation.	20163528
Chronic Infantile Neurological, Cutaneous, and Articular Syndrome, Neurogenic Inflammation, Urticaria	Altered Intercellular Communication	NOMID must be considered in any child with chronic urticaria of neonatal/infantile onset, particularly if associated with joint and/or neurological inflammation.	20163528
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The genotypes -174 GC/CC and -572 GG may confer susceptibility for the development of subclinical inflammation and type 2 diabetes in Mexican families.	20164544
Synapses, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Neurotransmitter system dysfunction and synapse loss have been recognized as hallmarks of Alzheimer's disease (AD).	20164549
Inflammation, Pterygium Of Conjunctiva And Cornea	Altered Intercellular Communication	The correlation of pterygium cell changes with pterygium activity supports the role of inflammation and its relationship with goblet cells in the pathogenesis of pterygium.	20164747
Granulomatous inflammation	Altered Intercellular Communication	A portion of the cyst's lining was replaced by granulomatous inflammation resulting from an earlier spontaneous partial rupture.	20164755
Inflammation, Infection	Altered Intercellular Communication	No deep pin track infections occurred; superficial skin inflammation was seen in 30%.	20166356
Corneal lesion, Inflammation	Altered Intercellular Communication	The patient presented a corneal lesion with marked superior thinning and no clinical signs of inflammation.	20168219
Choroidal Neovascularization	Altered Intercellular Communication	The purpose of this study was to report our experience with intravitreal bevacizumab for inflammation-related choroidal neovascularization in two tertiary centers.	20168273
Choroidal Neovascularization, Uveitis	Altered Intercellular Communication	Ten eyes of 10 patients (range, 14-78 years; mean age, 44 years) with underlying uveitis were treated with intravitreal bevacizumab for inflammation-related choroidal neovascularization from 2006 to 2008.	20168273
Inflammation, Choroidal Neovascularization, Inflammatory disorder	Altered Intercellular Communication	Intravitreal bevacizumab is an effective treatment for choroidal neovascularization related to inflammatory diseases when inflammation is controlled.	20168273
Tumor necrosis, Inflammation	Altered Intercellular Communication	Finally, we show that sEpoR is increased in the supernatant of a human erythroleukaemia cell line when stimulated by inflammatory mediators such as interleukin-6 and tumor necrosis factor alpha implying a link between inflammation and erythropoietin resistance.	20169072
Thrombosis	Altered Intercellular Communication	Acute infection-inflammation and coronary stent thrombosis: an observational study.	20169424
Inflammation	Altered Intercellular Communication	We present the case of a boy, who suffered inflammation of venous sinuses of cranial basis, when he was 6 years old.	20169891
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Plasma interleukin (IL)-1b and IL-6 are markers that predict the risk of inflammation in diabetes.	20170929
Inflammation	Altered Intercellular Communication	It accompanies local ophthalmological inflammation and its appearance during the course of this disease must be dealt with carefully.	20171431
Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Cardiovascular Diseases	Altered Intercellular Communication	Metabolic syndrome (MetS) is characterized by low-grade inflammation and confers an increased risk for cardiovascular disease.	20171637
Inflammation, Ulcer	Altered Intercellular Communication	This disease is characterized by ulcers and signs of acute inflammation on the membranous portion of the vocal folds with a prolonged clinical course.	20171831
Gastrointestinal inflammation, Protein-Losing Enteropathies	Altered Intercellular Communication	Intestinal inflammation is a component of the pathophysiology of protein-losing enteropathy after the Fontan operation.	20172140
Inflammation, Degenerative disorder	Altered Intercellular Communication	Inflammation plays an important role in many chronic degenerative diseases associated with aging, and social, economic, and behavioral factors that contribute to inflammation may lead to differential burdens of morbidity and mortality in later life.	20172904
Inflammation, Health-Related Behavior	Altered Intercellular Communication	Health-related behaviors and usage of medications related to inflammation accounted for substantial proportions of these associations.	20172904
Inflammation	Altered Intercellular Communication	These results highlight the fundamental causes of inflammation among older adults and suggest pathways through which social disparities in inflammation may be reduced.	20172904
Inflammation, Critical Illness	Altered Intercellular Communication	Future research focusing on the association between acute systemic inflammation and post-ICU outcome is warranted in order to improve long-term survival of critically ill patients.	20173056
Parkinson Disease, "Alzheimers Disease	Altered Intercellular Communication	Impaired neurotransmitter release in Alzheimer's and Parkinson's diseases.	20173332
Sarcoidosis, Inflammatory abnormality of the eye, Intraocular Lymphoma	Altered Intercellular Communication	Although primary intraocular lymphoma should always be in the differential diagnosis of older patients who present with signs of ocular inflammation, ophthalmologists must also consider other etiologies, including sarcoidosis.	20175273
Intraocular inflammation	Altered Intercellular Communication	To report clinical and epidemiologic findings of 11 patients with severe intraocular inflammation after intravitreal injection.	20175274
Intraocular inflammation	Altered Intercellular Communication	This is a single-center, retrospective, interventional case series of 11 patients with severe intraocular inflammation after intravitreal injection at 1 referral center.	20175274
Intraocular inflammation	Altered Intercellular Communication	During the examination period, we identified 11 cases of intraocular inflammation after intravitreal injection.	20175274
Dermatitis	Altered Intercellular Communication	Right leg magnetic resonance imaging (MRI) showed high signal areas on T(2)-weighted images on the subcutaneous fatty tissue, muscles and bone marrow, suggesting that skin inflammation extended to the bone marrow.	20175843
Inflammation, Scleroderma	Altered Intercellular Communication	Our observations suggest that MRI examination should be considered in patients with localized scleroderma to evaluate the extension of the inflammation.	20175843
Inflammation, Candida (fungus)	Altered Intercellular Communication	This case and a similar reported case suggest that Candida can sometimes cause cutaneous inflammation predominantly composed of eosinophils.	20175854
Inflammation, Immune-mediated	Altered Intercellular Communication	The STAT4 gene encodes a transcription factor which plays an important role in the development of inflammation of many immune-mediated diseases.	20176035
Inflammation, Vascular System Injuries	Altered Intercellular Communication	Sulfatides may play a physiological role on inflammation in vascular injury and the development of neointimal thickening.	20176357
Inflammation, Coronary Artery Disease, Atherosclerosis	Altered Intercellular Communication	The crucial role of T helper (Th) cells and chronic inflammation in atherosclerosis and coronary artery disease is no longer controversial.	20177960
Inflammatory disorder	Altered Intercellular Communication	IFN regulatory factor (IRF)-1 is a pleiotropic transcription factor involved in innate immunity and chronic inflammation disease.	20177960
Inflammation, Acanthosis, Ulceration, CTCAE, Spongiosis	Altered Intercellular Communication	Histological examination showed spongiosis and acanthosis in the stratum corneum, ulceration and inflammation with prevalently mononucleate cells and septate and branched fungal structures in the epidermis and in dermis.	20177971
Nonspecific interstitial pneumonia, Fibrosis Assessment, Pneumonia, Interstitial, Interstitial inflammation	Altered Intercellular Communication	Nonspecific interstitial pneumonia (NSIP) was initially defined in 1994 as a histopathologic pattern, characterized by the presence of varying proportions of lung interstitial inflammation and fibrosis, with a temporally uniform lung involvement, that can be found in the presence of a wide variety of clinical and radiologic contexts.	20178304
Inflammation, Obesity	Altered Intercellular Communication	Telomere length in relation to insulin resistance, inflammation and obesity among Arab youth.	20178511
Inflammation, Rupture, Dystrophic calcification, Calcinosis, Epithelial cyst	Altered Intercellular Communication	The presence of normal values of calcium and phosphorus along with this spectrum of changes in histology both support the theory that these form by dystrophic calcification of epithelial cysts in a progression that involves inflammation, rupture, calcification and obliteration of the cyst wall.	20178701
Inflammation, Atherosclerosis	Altered Intercellular Communication	Metabolic activation of monocytes has been suggested to be an important link between chronic inflammation, oxidative stress and the development of atherosclerosis.	20178722
Inflammatory disease of mucous membrane, Intestinal Diseases, Intestinal Pseudo-Obstruction	Altered Intercellular Communication	The diagnoses were enteropathy in 3, extreme short gut in 1, complex (associated mucosal inflammation and dysmotitlity) in 2, and intestinal pseudo-obstruction in 1.	20179643
Anxiety, CTCAE 3.0, Inflammation	Altered Intercellular Communication	NPSR1 is expressed in the brain, where it modulates anxiety and responses to stress, but also in other tissues and cell types including lymphocytes, the lungs, and the intestine, where it appears to be up-regulated in inflammation.	20179762
Inflammation, Fibrosis Assessment, Alcoholic Liver Diseases, Liver Stiffness	Altered Intercellular Communication	To test if inflammation also interferes with liver stiffness (LS) assessment in alcoholic liver disease (ALD) and to provide a clinical algorithm for reliable fibrosis assessment in ALD by FibroScan (FS).	20180235
Inflammation, prostatitis	Altered Intercellular Communication	Fifty-one (31.5%) of the total specimens presented pathological changes of chronic prostatitis, of which 44 had mild focal stromal, 5 mild focal stromal and periglandular and 2 mild focal periglandular inflammation.	20180403
Inflammation, Chronic prostatitis	Altered Intercellular Communication	Bacterial inflammation may play an important role in the etiology of chronic prostatitis.	20180403
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	These results suggest that cysteine cathepsins have a major role in inflammation at least in rheumatoid arthritis.	20180636
Inflammation, Atrophic	Altered Intercellular Communication	Atrophy development was related to age (OR 1.23) and to the severity of chronic inflammation in the corpus mucosa at baseline (OR 8.98).	20180646
Inflammation, Atrophic	Altered Intercellular Communication	The incidence of atrophy of the corpus mucosa was 1.4 per 100 person years with a positive relation to age and to the degree of chronic inflammation at baseline.	20180646
Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Atherosclerosis	Altered Intercellular Communication	The relationship of serum ferritin with early cardiovascular disease (CVD), particularly atherosclerosis, has not been evaluated extensively, particularly with accounting for inflammation.	20181783
Inflammation, Atherosclerosis	Altered Intercellular Communication	In conclusion, carotid atherosclerosis was positively associated with serum ferritin in individuals free from subclinical inflammation based on AGP.	20181783
Presenile dementia, Lewy Bodies, Parkinson Disease	Altered Intercellular Communication	Neurotransmitter changes in dementia with Lewy bodies and Parkinson disease dementia in vivo.	20181924
Waldenstrom Macroglobulinemia	Altered Intercellular Communication	Immune-related and inflammatory conditions and risk of lymphoplasmacytic lymphoma or Waldenstrom macroglobulinemia.	20181958
Communicable Diseases, Allergic	Altered Intercellular Communication	We evaluated a wide range of autoimmune, infectious, allergic, and inflammatory conditions.	20181958
Infarction, Inflammation	Altered Intercellular Communication	Diffusion-weighted imaging showed restricted diffusion in the distal intraorbital segment of the optic nerve, consistent with infarction attributed to compression or inflammation of the vessels serving the optic nerve and retina.	20182203
Inflammation	Altered Intercellular Communication	A 76-year old man presented with inflammation of the eyelids and underlying orbital soft tissue.	20182211
Inflammation, Atrophic	Altered Intercellular Communication	A biopsy disclosed inflammation and atrophy of the orbital fat consistent with LEP.	20182211
Exanthema, Orbital Pseudotumor, Enophthalmos	Altered Intercellular Communication	LEP should be considered in patients with a characteristic rash and orbital inflammation and may cause acquired enophthalmos.	20182211
ARCN1 gene, Inflammation, Arterial Stiffness	Altered Intercellular Communication	We hypothesised that sub-clinical right (RV) and left ventricular (LV) dysfunction occurs in patients with COPD, related to the severity of airflow obstruction, arterial stiffness and systemic inflammation.	20185285
Inflammation, Vasculitis, Central Nervous System	Altered Intercellular Communication	Leptomeningeal biopsies of two cases revealed perivascular inflammation, indicating central nervous system vasculitis.	20185466
Inflammation, Malnutrition, Diabetes Mellitus, Cardiovascular Diseases	Altered Intercellular Communication	These highly fatigued patients exhibited a significantly higher risk for cardiovascular events (hazard ratio: 2.17; P < 0.01), with the relationship independent of the well-known risk factors, including age, diabetes, cardiovascular disease history, and inflammation and malnutrition markers.	20185601
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	We aimed to investigate whether it could act as a link between low-grade chronic inflammation and diabetes.	20185737
Inflammation, Non-alcoholic Fatty Liver Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dyslipidemias	Altered Intercellular Communication	Nonalcoholic fatty liver disease is highly prevalent in obese and type 2 diabetic individuals and is strongly associated with dyslipidemia and inflammation.	20185740
Steatohepatitis, Weight decreased, Inflammation	Altered Intercellular Communication	Addition of ezetimibe to a moderate weight loss diet in obese subjects can significantly improve hepatic steatosis, inflammation, and LDL-apoB-100 metabolism.	20185740
Inflammation, Retinal Diseases	Altered Intercellular Communication	Age-related macular degeneration: the molecular link between oxidative damage, tissue-specific inflammation and outer retinal disease: the Proctor lecture.	20185837
Inflammation, Cavernous Sinus Thrombophlebitis	Altered Intercellular Communication	Clival inflammation with cavernous sinus thrombophlebitis and orbital subperiosteal abscess--case report.	20185888
Inflammation, Cavernous Sinus Thrombophlebitis, Infection, Abducens Nerve Diseases	Altered Intercellular Communication	A 64-year-old woman presented with a very rare case of three infectious lesions, cavernous sinus thrombophlebitis, clival inflammation, and orbital subperiosteal abscess (SPA), manifesting as abducens palsy.	20185888
Inflammation	Altered Intercellular Communication	The clival lesion was approached by an endonasal transsphenoidal route and diagnosed as inflammation.	20185888
Hypophysitis, CTCAE, Communicable Diseases, Granulomatous inflammation, Inflammatory, Granulomatosis with polyangiitis	Altered Intercellular Communication	An inflammatory sellar mass is very rare but includes a variety of noninfectious causes including lymphocytic hypophysitis, granulomatous inflammation and Wegener's granulomatosis.	20186358
Inflammation	Altered Intercellular Communication	One possible explanation relates to systemic inflammation, which is associated with these adverse health outcomes.	20186494
Inflammatory Bowel Diseases, Inflammation, Malnutrition, Anemia	Altered Intercellular Communication	Decreases in GPx activity corresponded with IBD activity, anemia, inflammation, and malnutrition.	20186929
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In UC, catalase activity corresponded indirectly with UC endoscopic activity and inflammation and directly with hemoglobin.	20186929
Inflammation, Anemia	Altered Intercellular Communication	SOD1, GPx1, and CAT activities are differently affected by the disease type, activity, anemia, inflammation, oxidative stress, and treatment.	20186929
Inflammation, Fibrosis Assessment, Mirizzi Syndrome, Gallbladder, Hypertension, CTCAE	Altered Intercellular Communication	When there is excess inflammation, fibrosis and portal hypertension around gall bladder or in presence of Mirizzi syndrome, bile ducts and hepatic artery may be possibly damaged during dissection of Calot triangle.	20187468
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Specific chemokines contribute to vascular inflammation and may be useful biomarkers to detect atherosclerosis.	20187767
Communicable Diseases, Inflammation	Altered Intercellular Communication	Seven miRNAs related to inflammation or infection were included in the present study.	20188071
Inflammation	Altered Intercellular Communication	Adiponectin is associated with inflammation and oxidative stress.	20188385
Inflammation, Metabolic Problems	Altered Intercellular Communication	Unequivocal evidence has emerged linking inflammation to the risk of metabolic problems.	20189773
Inflammation, Schizophrenia	Altered Intercellular Communication	Previous research also has suggested a relationship between inflammation and schizophrenia.	20189773
Inflammation, Psychiatric, Metabolic Syndrome X, Schizophrenia	Altered Intercellular Communication	The present study examined whether white blood cell count (WBC), a marker of systemic inflammation, is associated with metabolic syndrome and psychiatric symptoms in non-diabetic patients with schizophrenia.	20189773
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation and oxidative stress (OS) are cardiovascular risk factors in patients with chronic kidney disease.	20190028
HD Term Type, Inflammation	Altered Intercellular Communication	The OSND thus provides a comprehensive scoring system with significant associations with prospective hospitalization and mortality in chronic HD patients as well as measures of nutrition and inflammation.	20190238
Inflammation, Malnutrition, Diabetes Mellitus	Altered Intercellular Communication	After adjustment for additional parameters of inflammation and malnutrition as well as diabetes, the linear component was more significant in women (P = 0.0018) than in men (P = 0.023).	20190241
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The circulating soluble TRAIL is a negative marker for inflammation inversely associated with the mortality risk in chronic kidney disease patients.	20190248
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Circulating sTRAIL is a negative marker for inflammation and is inversely associated with the mortality risk in CKD patients.	20190248
Inflammation, Heart failure	Altered Intercellular Communication	Marked increase in the LV expression of LOX-1 in failing hearts may contribute to increased serum levels, and might be involved in chronic inflammation during the development of heart failure.	20190428
Diffuse alveolar hemorrhage	Altered Intercellular Communication	The description of bronchoalveolar lavage fluid findings showed an alveolar hemorrhage and neutrophilic inflammation.	20190477
Inflammation, Fever, CTCAE, Dry cough	Altered Intercellular Communication	The patient presented intermittent 40 masculineC fever evolving over 40 days, dry cough and painless bilateral cervical adenomegaly, showing no signs of inflammation.	20191206
Inflammation, Spondylitis	Altered Intercellular Communication	Systematic assessment of inflammation by magnetic resonance imaging in the posterior elements of the spine in ankylosing spondylitis.	20191485
Inflammation	Altered Intercellular Communication	Inflammation was scored dichotomously (present/absent) in each posterior structure.	20191485
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Mutuality's prospective beneficial effects on inflammation in female patients with rheumatoid arthritis.	20191496
Inflammation	Altered Intercellular Communication	Hypothesizing that mutuality has a beneficial impact on inflammation, we tested potentially causal relations of couple mutuality with erythrocyte sedimentation rate (ESR) in prospective data.	20191496
Refractory anemias, Inflammation	Altered Intercellular Communication	Patients with RA reporting more mutuality had less inflammation at subsequent time points, but inflammation had no effect on subsequent reports of mutuality.	20191496
Inflammation, Periodontitis, Diabetes Mellitus	Altered Intercellular Communication	Although worldwide evidence tends to prove that diabetes adversely affects periodontal health, there are insufficient clues indicating whether periodontitis may aggravate metabolic control and systemic inflammation.	20192862
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Salivary MMP-8 and OPG concentrations were elevated regardless of periodontal inflammation in patients with diabetes.	20192865
Inflammation, Fecal Incontinence, Anal pain	Altered Intercellular Communication	Two patients experienced mild anal incontinence when followed-up to 6 months; 2 patients suffered mild anal pain during defecation due to slight anastomotic inflammation 2 and 4 months after the operation, respectively.	20193398
Autoimmune Diseases, Inflammation, TYMS wt Allele, Gilles de la Tourette syndrome	Altered Intercellular Communication	Post-infectious autoimmunity has been implicated in pathogenesis of Tourette's syndrome (TS) but no evidence of inflammation in central nervous system has been reported yet.	20193755
Inflammation	Altered Intercellular Communication	Multiple markers of inflammation and weight status: cross-sectional analyses throughout childhood.	20194272
Inflammation, Blood Vessel	Altered Intercellular Communication	Elevated inflammatory markers in very young obese children are particularly concerning, because inflammation may cause long-term, cumulative vascular damage.	20194272
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Among investigated molecules, only MMP2 was independently related to inflammation and fibrosis according to grading (P=0.036) and staging (P=0.032) score.	20195229
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In addition MMP2 is related to inflammation and fibrosis as assessed by liver biopsy and laboratory features.	20195229
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	Caloric restriction shortens lifespan through an increase in lipid peroxidation, inflammation and apoptosis in the G93A mouse, an animal model of ALS.	20195368
Inflammation	Altered Intercellular Communication	We conclude that CR increases lipid peroxidation, inflammation and apoptosis, while decreasing mitochondrial bioenergetic efficiency, protein oxidation and stress response in G93A mice.	20195368
Gastrointestinal inflammation	Altered Intercellular Communication	Recent evidence suggests a crucial role of the endocannabinoid system, including the cannabinoid 1 receptor (CNR1), in intestinal inflammation.	20195480
Inflammation, Giant Cell Arteritis	Altered Intercellular Communication	Giant cell arteritis is characterized primarily by inflammation in certain large and medium-sized arteries.	20197597
Inflammation, Hemorrhage, Edema, Pulmonary Hypertension	Altered Intercellular Communication	Furthermore, Hif2a heterozygosity resulted in partial protection against vascular remodeling, hemorrhage, and edema, but not inflammation, in VhlR/R lungs, suggesting a selective role for HIF-2alpha in the pulmonary pathology and thereby providing insight into the mechanisms underlying pulmonary hypertension.	20197624
Coronary Artery Disease, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic Syndrome X, Cardiovascular system	Altered Intercellular Communication	Therefore, type 2 diabetes may further increase the risk of coronary artery disease in the metabolic syndrome subjects through cardiovascular inflammation.	20197633
Inflammation	Altered Intercellular Communication	Therefore, we proposed that the dissection and the stenosis are directly induced by the inflammation of THS.	20198499
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Lung diseases	Altered Intercellular Communication	The integrated project COSYCONET, as part of the competence network ASCONET funded by the BMBF, has the aim to investigate the relationship between the pulmonary disorder, comorbidities and systemic inflammation in patients with chronic obstructive pulmonary disease (COPD) by adopting cross-sectional as well as longitudinal analyses.	20198540
Inflammation, Atheroma, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Local non-esterified fatty acids correlate with inflammation in atheroma plaques of patients with type 2 diabetes.	20200316
Inflammation, Dental Plaque, Atherosclerosis, diabetic	Altered Intercellular Communication	Atherosclerosis is prevalent in diabetic patients, but there is little information on the localization of nonesterified fatty acids (NEFAs) within the plaque and their relationship with inflammation.	20200316
Diabetes with coma (disorder), Inflammation	Altered Intercellular Communication	We sought to characterize the NEFA composition and location in human diabetic atheroma plaques by metabolomic analysis and imaging and to address their relationship with inflammation activity.	20200316
Inflammation	Altered Intercellular Communication	We hypothesize that NEFA may be produced locally and contribute to local inflammation.	20200316
Inflammation, Adenoma of large intestine	Altered Intercellular Communication	Antioxidant micronutrients and biomarkers of oxidative stress and inflammation in colorectal adenoma patients: results from a randomized, controlled clinical trial.	20200432
Inflammation, Diverticular Diseases	Altered Intercellular Communication	Therefore the chronic inflammation and local disturbance of epithelium regeneration were established in diverticular disease.	20201300
Colitis	Altered Intercellular Communication	The severity of duodenal and colonic inflammation was determined by endoscopic and histologic scores.	20201621
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	The histopathological findings were consistent with glaucoma and chronic inflammation.	20202555
Inflammation, Carotid Stenosis	Altered Intercellular Communication	Mycophenolate mofetil attenuates plaque inflammation in patients with symptomatic carotid artery stenosis.	20202636
Inflammation, Neoplasm Metastasis, Neoplasms, Vascular Invasion Assessment, Liver Cirrhosis	Altered Intercellular Communication	Compared with seronegative-HBsAg ICC patients, seropositive-HBsAg ICC patients were younger, more frequently male and had a higher proportion of abnormal aminotransferase and serum alpha-fetoprotein (AFP) level, histological inflammation and cirrhosis, right-lobe focus, poor tumour differentiation, tumour encapsulation and microvascular invasion; had a lower proportion of abnormal serum carbohydrate antigen 19-9 (CA19-9) level and lymphatic metastasis.	20202823
Communicable Diseases, Inflammation	Altered Intercellular Communication	The origin of this protein remodeling (involving the physical or functional absence of CFTR, infection, inflammation, or high adrenergic tone) deserves further investigation.	20203292
Inflammation, Heart failure	Altered Intercellular Communication	However, recent investigations strongly suggest that increased adiponectin production in patients with heart failure is a part of compensatory mechanisms against oxidative stress and inflammation.	20204504
Fracture, Osteopenia	Altered Intercellular Communication	Our study suggests progressive hormonal changes that may contribute to severe bone loss during the year following hip fracture.	20204599
Inflammation, Restenosis, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis and restenosis are largely ruled by inflammation.	20206356
Inflammation	Altered Intercellular Communication	At surgery, inflammation remained in the middle ear, and edematous pale mucosal tissue was noted around the stapes and ossicular chain.	20206453
Inflammation, Granulation finding, Necrosis	Altered Intercellular Communication	Histopathologic examination showed inflammation and granulation tissue, but no caseating necrosis or acid-fast bacilli.	20206453
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Since CRP is a marker of inflammation, this finding suggests that inflammation may play an important role in the natural history of advanced prostate cancer.	20207556
Peripheral ulcerative keratitis, Corneal Stroma, Inflammation	Altered Intercellular Communication	Peripheral ulcerative keratitis (PUK) is a disorder consisting of a crescent-shaped destructive inflammation of the perilimbal corneal stroma.	20209701
Hemorrhage, Tissue Adhesions	Altered Intercellular Communication	A VA was defined as the accidental bleeding during dissection, depending on the surgeon and/or inflammatory conditions, adhesions, and so on.	20210667
Chronic inflammation, Sarcolemma, skeletal muscle tissue regeneration, Doctor of Dental Medicine, Muscular Dystrophy, Duchenne, Disease	Altered Intercellular Communication	Duchenne muscular dystrophy (DMD), a lethal disorder characterized by dystrophin absence, courses with chronic inflammation, sarcolemmal damage, and skeletal muscle degeneration.	20210854
Inflammation, Doctor of Dental Medicine	Altered Intercellular Communication	Among the multiple pathogenic mechanisms proposed for DMD, oxidative stress and inflammation are directly involved in the dystrophic process.	20210854
ARCN1 gene, Inflammation	Altered Intercellular Communication	Local inflammation occurs before systemic inflammation in patients with COPD.	20210891
ARCN1 gene, Inflammation	Altered Intercellular Communication	COPD is associated not only with an abnormal inflammatory response in the lung but also with systemic inflammation, including systemic oxidative stress, activation of circulating inflammatory cells and increased circulating levels of inflammatory cytokines.	20210891
ARCN1 gene, Inflammation	Altered Intercellular Communication	Understanding the nature and course of systemic inflammation in COPD is important given the potential for anti-inflammatory therapy.	20210891
ARCN1 gene, Inflammation	Altered Intercellular Communication	This study explored whether local and systemic inflammation occur concurrently in patients with COPD.	20210891
ARCN1 gene, Inflammation	Altered Intercellular Communication	Systemic inflammation may be present in patients with severe or very severe COPD.	20210891
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Circulating surfactant protein -D is low and correlates negatively with systemic inflammation in early, untreated rheumatoid arthritis.	20211020
Inflammation	Altered Intercellular Communication	Anti-microbial and anti-inflammatory properties have been attributed to multimeric SP-D variants, while trimeric subunits per se have been suggested to enhance inflammation.	20211020
Inflammation	Altered Intercellular Communication	The exclusive presence of trimeric SP-D in affected joints may contribute to the maintenance of joint inflammation.	20211020
Metabolic Syndrome X, Cardiovascular Diseases, Presenile dementia, Diabetes Mellitus, Inflammatory disorder, Malignant Neoplasms, Arthritis	Altered Intercellular Communication	Thus, the significance of our findings is that the zingerone treatment may provide some preventive measure against chronic inflammatory conditions that underlie many age-related inflammatory diseases, such as metabolic syndrome, cardiovascular disease, dementia, arthritis, diabetes, osteoprosis, and cancers.	20211236
Inflammation, Peripheral motor neuropathy	Altered Intercellular Communication	The favorable response to treatment with IV immunoglobulins and the presence of IgM antibodies to the glycolipid GM1 are indications that inflammation underlies multifocal motor neuropathy (MMN) pathogenesis.	20211906
Anemia, Critical Illness, Intradermal Route of Drug Administration	Altered Intercellular Communication	Inflammation-induced anemia is frequent among critically ill patients and can be aggravated by true iron deficiency (ID) resulting from blood losses.	20213069
Inflammation, Intradermal Route of Drug Administration	Altered Intercellular Communication	The serum hepcidin level controls the availability of iron for erythropoiesis, and its determination offers new perspectives for the diagnosis of ID in the presence of inflammation.	20213069
Inflammation, Intradermal Route of Drug Administration	Altered Intercellular Communication	Hepcidin levels may be suppressed by ID even in case of inflammation.	20213069
Pain Distress Question, Inflammation	Altered Intercellular Communication	The relationship of Modic change to pain and inflammation remains to be unclear.	20213295
Inflammation	Altered Intercellular Communication	A 47-year-old man presented with bilateral ERD accompanied by anterior and posterior segment inflammation.	20213612
Inflammation, Urolithiasis, Chronic pyelonephritis, Hyperuricemia	Altered Intercellular Communication	It is shown that urisan contributes to intensification of renal filtration function, to reduction of hyperuricemia and urine pH, intensification of uric acid excretion, continuation of inflammation remission, attenuation of proteinurea in urolithiasis patients with exacerbation of chronic pyelonephritis.	20213910
Granulomatous inflammation, Albinism, Fibrosis Assessment, Nystagmus	Altered Intercellular Communication	He was born of a consanguineous marriage, had occulo-cutaneous albinism, nystagmus, decreased visual acuity, refractory errors, pulmonary fibrosis and granulomatous inflammation of the colon.	20214008
Whole-Body Irradiation, Traumatic, physiopathological	Altered Intercellular Communication	Hormonal dysfunction is a known consequence of moderate and severe traumatic brain injury (TBI).	20214417
Inflammation, Blood Glucose	Altered Intercellular Communication	Lipoprotein concentrations, glycemia, and inflammation parameters were determined.	20215451
Fibrous, Inflammation, Pleural plaque, Cleft ala nasi	Altered Intercellular Communication	Histologically, lesions were subdivided into 3 types: (1) "plaque-like" consisting of dense fibrous tissue with clefts without significant inflammation identical to a pleural plaque (5 cases); (2) "inflammatory sclerotic" with dense fibrous tissue containing lymphocytes (diffusely or aggregates or germinal centers), plasma cells, and an increased capillary network (6 cases); and (3) "myofibroblastic" consisting of reactive looking tissue-culture-like spindle cells with numerous capillaries and sparse chronic inflammation (2 cases).	20216379
Coronary angiography, Inflammation	Altered Intercellular Communication	Total homocysteine in patients with angiographic coronary artery disease correlates with inflammation markers.	20216983
Psychological Distress, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Although a substantial body of research points to a link between psychological distress and inflammatory responses in middle-aged and older adults, particularly those with cardiovascular disease, the relationship between inflammation and distress in young, healthy individuals has not been established.	20219150
Symptoms, Inflammation	Altered Intercellular Communication	In this observational study, parenteral corticosteroids were associated with a statistically significant reduction in symptoms, but no statistically significant reduction in US-detected synovial inflammation.	20219784
Inflammation	Altered Intercellular Communication	The latter finding may, however, reflect the relatively low levels of synovial inflammation detected ultrasonagraphically in hand joints.	20219784
Bronchial Hyperreactivity	Altered Intercellular Communication	Using adoptive transfer of Unc119-knockdown CD4 T cells, we show a critical role for Unc119 in the development of eosinophilic inflammation of airways, mucus production, and bronchial hyperreactivity in a mouse model.	20220094
Communicable Diseases, Inflammation, Cerebral Palsy	Altered Intercellular Communication	In utero exposure to infection or inflammation is a strong and independent predictor of cerebral palsy.	20220110
Autoimmune Diseases, Idiopathic Inflammatory Myopathies, Inflammation, Proximal muscle weakness	Altered Intercellular Communication	The idiopathic inflammatory myopathies are systemic autoimmune diseases characterized by chronic inflammation, resulting in the progressive weakness of the proximal muscles.	20221841
Inflammation, Primary malignant neoplasm, Hypogonadism	Altered Intercellular Communication	Hypogonadism has been linked with systemic inflammation and opioid use in males with advanced cancer.	20221887
Inflammation, Hypogonadism, Pancreatic carcinoma	Altered Intercellular Communication	In males with pancreatic cancer, systemic inflammation and opioid use are associated with hypogonadism.	20221887
Inflammation, Chronic disease	Altered Intercellular Communication	It is implicated in the development of a variety of chronic disease states and is associated with increased levels of inflammation and oxidative stress.	20222968
Inflammation, Weight decreased, Chronic disease	Altered Intercellular Communication	Our data suggest that the meal replacement diet plan evaluated was an effective strategy for producing robust initial weight loss and for achieving improvements in a number of health-related parameters during weight maintenance, including inflammation and oxidative stress, two key factors more recently shown to underlie our most common chronic diseases.	20222968
Rheumatoid Arthritis, Spondylitis, Reactive systemic amyloidosis	Altered Intercellular Communication	Secondary amyloidosis of the bladder is of the AA type, which is more common in females and mainly secondary to rheumatoid arthritis, but also to ankylosing spondylitis and long-standing chronic inflammatory conditions.	20223142
Inflammation	Altered Intercellular Communication	The objective was to evaluate inflammation in echolucent carotid artery plaques.	20223427
Inflammation, Dental Plaque	Altered Intercellular Communication	Our results substantiate previous findings of an association between plaque FDG uptake and inflammation.	20223427
Inflammation	Altered Intercellular Communication	Echolucent plaques exhibit a wide range of inflammatory activity, whereas echorich plaques show little inflammation.	20223427
Inflammation	Altered Intercellular Communication	It has been previously demonstrated that systemic inflammation is associated with PAD and its clinical outcomes.	20223619
Inflammation	Altered Intercellular Communication	Improving the systemic milieu of insulin resistance and inflammation in these high-risk patients may lead to reduced morbidity and mortality.	20223619
Inflammation, Amyloidosis	Altered Intercellular Communication	Treatment with colchicine reduces inflammation and the risk of developing amyloidosis.	20224617
Ischemia, Gastrointestinal inflammation	Altered Intercellular Communication	The octn1 ( -/- ) mice exhibited greater susceptibility to intestinal inflammation under the ischemia and reperfusion model.	20224991
Degenerative polyarthritis, Inflammation, Obesity	Altered Intercellular Communication	Obesity, as a primary risk factor for osteoarthritis (OA), has been shown to alter joint loading, but may also result in metabolic changes characterized by chronic, low-level inflammation due to increased circulating levels of adipose-derived cytokines, or "adipokines."	20225314
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation was present on follow-up biopsy specimens 4 weeks later.	20227579
Inflammation, Swelling	Altered Intercellular Communication	No more gingival inflammation or swelling was observed.	20228992
Inflammation	Altered Intercellular Communication	Reverse correlation was found with transferrin (r = -0.323, p < 0.0001), albumin (r = -0.251, p = 0.003), and S-Fe (r = -0.205, p = 0.02), parameters known to decrease during inflammation.	20229122
Inflammation	Altered Intercellular Communication	Inflammation increased levels of NT-proBNP more than BNP, resulting in an increased NT-proBNP/BNP ratio.	20229122
Inflammation, Neoplasms	Altered Intercellular Communication	The specificity in patients with the endoscopic findings described as 'negative', 'inflammation', 'scar tissue', 'flat lesion', 'suspicious for tumour', and 'exophytic tumour' was 89.8%, 89.9%, 85.0%, 77.1%, 63.2% and 48.6%, respectively (P < 0.001).	20230393
Dysplasia, Stomach Carcinoma, Infection caused by Helicobacter pylori, Stomatitis, Intestinal metaplasia	Altered Intercellular Communication	This paper shows analysis of the association of the 802C>T polymorphism of the NOD2/CARD15 gene with the occurrence of the chronic inflammation of the gastric mucosa associated with the Helicobacter pylori infections, development of intestinal metaplasia and dysplasia and, in the result of this, gastric cancer.	20230816
Inflammation, Atherosclerosis	Altered Intercellular Communication	Our findings further support a role for inflammation in the accelerated form of atherosclerosis in IRD patients, and suggest that certain inflammatory pathways, such as the enhanced endothelial cell activation and the RANK ligand/RANK/OPG system, may be of particular importance.	20231178
Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of the joints, which may lead to structural damage of the cartilage and bone.	20231205
Airway structure, Asthma, Bronchoconstriction	Altered Intercellular Communication	The cysteinyl leukotrienes cause bronchoconstriction, increased mucus production and airway inflammation, three major features of asthma.	20232571
Rheumatoid Arthritis, destruction joint, Inflammation	Altered Intercellular Communication	Biomarkers in early rheumatoid arthritis: longitudinal associations with inflammation and joint destruction measured by magnetic resonance imaging and conventional radiographs.	20233753
Synovitis, Inflammation, Edema of bone marrow	Altered Intercellular Communication	Consistent associations, both with MRI inflammation (synovitis and bone marrow oedema) and DAS28 were found for sYKL-40 and sMMP-3 in addition to C-reactive protein at baseline and in longitudinal analyses.	20233753
destruction joint, Arthritis, C-telopeptide	Altered Intercellular Communication	Levels of sCTX-I and uCTX-II were significant predictors of progressive joint destruction, whereas sMMP-3 and sYKL-40 were merely markers of joint inflammation.	20233753
Inflammation, Fever, CTCAE	Altered Intercellular Communication	In early July of the following year, he was re-admitted to our hospital because of continuous high fever, despite no any inflammation.	20235483
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	It has been reported that small airway inflammation is closely associated with the severity of airflow limitation in COPD (chronic obstructive pulmonary disease).	20236091
Inflammation, Lung diseases	Altered Intercellular Communication	Mechanical ventilation with high tidal volume induces inflammation in patients without lung disease.	20236550
Lung Injury, Pneumonitis	Altered Intercellular Communication	The use of lower tidal volumes may limit pulmonary inflammation in mechanically ventilated patients even without lung injury.	20236550
Inflammation	Altered Intercellular Communication	Elderly individuals with a strong innate inflammatory system, or ongoing systemic inflammation (or both), might be most susceptible to these outcomes.	20236772
Inflammation, Damage	Altered Intercellular Communication	MSUS was performed in all patients in both hands and wrists, evaluating the presence of inflammation within joints and periarticular tissues, and the existence of permanent joint damage.	20236956
Inflammation, Neoplasms	Altered Intercellular Communication	(18)F-FLT PET/CT may have an advantage over (18)F-FDG PET/CT in differentiating inflammation from tumor.	20237030
Inflammation, conjunctiva	Altered Intercellular Communication	IL1B expression was elevated in the presence of either conjunctival bacterial infection (P = 0.011) or inflammation (P = 0.002).	20237245
Inflammation, Chlamydia Infections	Altered Intercellular Communication	TNF expression was greater in the Mandinka ethnic group (P < 0.0001), and it was increased when clinical inflammation was associated with nonchlamydial bacterial infection (P = 0.012).	20237245
Bacterial Infections, Conjunctivitis	Altered Intercellular Communication	MMP-9 expression increased when conjunctival inflammation was associated with bacterial infection (P = 0.007).	20237245
Inflammation	Altered Intercellular Communication	Peritumoral connective tissue was generally unremarkable, but chronic inflammation was present in five cases.	20237984
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Alveolar	Altered Intercellular Communication	Inflammation is an important constituent of the pathology of chronic obstructive pulmonary disease (COPD), leading to alveolar destruction and airway remodelling.	20298300
Communicable Diseases, Inflammation	Altered Intercellular Communication	It is characterised by pathological dilatation of the bronchi thought to result from infection and inflammation.	20298369
Inflammation, Bronchiolitis, Pneumonia	Altered Intercellular Communication	Minor findings included bronchiolitis, organizing pneumonia and peribronchial inflammation.	20298381
allergic inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	Seasonal allergy is an interesting model to study the pathophysiological mechanisms involved in allergic inflammation.	20298416
Birch Pollen IgE Measurement, Inflammation, Asthma, Rhinitis	Altered Intercellular Communication	Bronchial allergen challenge with inhalation of birch pollen gives a similar inflammatory response in the airway but less systemic inflammation than seasonal exposure in birch pollen allergic patients with asthma and rhinitis.	20298416
Airway structure	Altered Intercellular Communication	Despite active airway inflammation, indicating need for treatment symptoms may be poorly perceived and influence on quality of life.	20298418
Inflammation	Altered Intercellular Communication	Open surgical repair of these lesions can be challenging due to the elevated venous pressure and surrounding inflammation.	20299180
Inflammation, Obesity	Altered Intercellular Communication	It has been observed that restrictive pulmonary function is associated with obesity and C-reactive protein (CRP), an indicator for systemic inflammation.	20299196
Obesity	Altered Intercellular Communication	We evaluated body composition and CRP as a categorical variable (non-obesity, percentage body fat 75 percentile; low-inflammation, CRP 75 percentile) and constructed 4 groups, which were non-overlapping (reference, inflammatory, obese, obese and inflammatory).	20299196
Inflammation	Altered Intercellular Communication	In summary, the coexistence of high fat accumulation and systemic subclinical inflammation is associated with restrictive pulmonary function.	20299196
Trauma, Nervous System	Altered Intercellular Communication	Neurotransmitter and Krebs cycle intermediate depletion in this model represent novel findings toward uncovering the mechanism of neuronal injury.	20299259
Berylliosis, Pneumonitis, cannabidiol	Altered Intercellular Communication	Chronic beryllium disease (CBD) is a CD4(+) T cell-mediated disorder characterized by persistent lung inflammation.	20299529
Tumor necrosis, Chronic Obstructive Airway Disease, Inflammation	Altered Intercellular Communication	Tumor necrosis factor-{alpha} rs361525 polymorphism is associated with increased local production and downstream inflammation in chronic obstructive pulmonary disease.	20299531
Inflammation	Altered Intercellular Communication	Their lung secretions contained more IL-8 and myeloperoxidase, consistent with downstream inflammation.	20299531
Airway structure, ARCN1 gene	Altered Intercellular Communication	Inhaled corticosteroids (ICS) have proved disappointing at reducing airway inflammation in COPD.	20299628
Airway structure, ARCN1 gene	Altered Intercellular Communication	Combination therapy with an inhaled corticosteroid and low-dose theophylline may attenuate airway inflammation in patients with COPD.	20299628
Cataract, Inflammatory abnormality of the eye, Dry Eye Syndromes	Altered Intercellular Communication	The addition of HP-Guar to regular treatment after cataract surgery reduces ocular surface inflammation and dry eye signs and symptoms.	20300126
Hepatic inflammation	Altered Intercellular Communication	In older adults (age > or = 48 years), daily fructose consumption was associated with increased hepatic inflammation (P < 0.05) and hepatocyte ballooning (P = 0.05).	20301112
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Severity of inflammation and fibrosis were not significantly different between case and control groups (P = 0.69), and between smokers and nonsmokers with PANDO (P = 0.15).	20302403
melanoma, Inflammation	Altered Intercellular Communication	Our findings, although preliminary, support the notion that the differential biology of melanoma at the extremes of age is driven, in part, by deregulation of microRNA expression and by fine tuning of miRs that are already known to regulate cell cycle, inflammation, Epithelial-Mesenchymal Transition (EMT)/stroma and more specifically genes known to be altered in melanoma.	20302635
Autoimmune Diseases, Inflammation, Immunity	Altered Intercellular Communication	CD4(+)CD25(+) regulatory T (Treg) cells and Th17 cells, subsets of T-helper cells, play important roles in peripheral immunity and their imbalance leads to the development of tissue inflammation and autoimmune diseases.	20302843
Inflammation	Altered Intercellular Communication	Angiotensin-converting enzyme (ACE) plays an important role in the physiological control of blood pressure and inflammation.	20303010
Inflammation, Giant Cell Arteritis, Takayasu Arteritis	Altered Intercellular Communication	(1,2) Histopathology usually reveals granulomatous inflammation affecting arterioles and small arteries of the parenchyma and/or leptomeninges, similar to that seen in Takayasu's or giant cell arteritis.	20303761
Vasculitis, Primary angiitis of the central nervous system, Idiopathic Inflammatory Myopathies, Vasculitis, CTCAE	Altered Intercellular Communication	Primary angiitis of the central nervous system (PACNS), also called primary CNS vasculitis, is an idiopathic inflammatory condition affecting only intracranial and spinal cord vessels, particularly medium-sized and smaller arteries and arterioles.	20303761
Communicable Diseases, Inflammation	Altered Intercellular Communication	Inflammation is an essential immune response that enables survival during infection or injury and maintains tissue homeostasis under a variety of noxious conditions.	20303867
Inflammation, Malignant neoplasm of ovary	Altered Intercellular Communication	Ovarian carcinomas are associated with increased inflammation which is based upon an up-regulation of inducible cyclooxygenase-2 (COX-2).	20304053
Temporal - Regional site descriptor, Pleurisy	Altered Intercellular Communication	The decrease observed from postoperative day 1 and thereafter suggests the action of the immunosuppression agents and a temporal reduction in pleural inflammation.	20304185
Rheumatoid Arthritis, Acute and chronic inflammation	Altered Intercellular Communication	Synoviocyte-derived angiopoietin-like protein 2 contributes to synovial chronic inflammation in rheumatoid arthritis.	20304962
Inflammation	Altered Intercellular Communication	Several proinflammatory cytokines derived from both infiltrating inflammatory cells and activated resident cells within the RA joint play a fundamental role in the processes that cause inflammation.	20304962
Refractory anemias, Inflammation, destruction joint	Altered Intercellular Communication	Therefore, an effort has been made to identify other key regulators of inflammation in articular structures to develop new therapies to suppress synovial inflammation and joint destruction in RA.	20304962
Inflammation, Obesity	Altered Intercellular Communication	Adipose tissue-derived angiopoietin-like protein 2 (Angptl2) activates an inflammatory cascade in endothelial cells and induces chemotaxis of monocytes/macrophages in obesity, resulting in initiation and propagation of inflammation within adipose tissues and obesity-related metabolic diseases.	20304962
Autoimmune Thyroid Disease Pathway, Colorectal Carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Increased incidence of mostly autoimmune thyroid disease has been associated with breast and other malignancies, and thyroid hormone levels might also be associated with risk of colorectal cancer (CRC).	20305129
Inflammation, Rheumatoid Arthritis, destruction joint	Altered Intercellular Communication	Cytokines such as TNF-alpha and IL-6, play key roles in driving the inflammation and synovial cell proliferation that characterize rheumatoid arthritis and joint destruction.	20306675
Fibrosis Assessment, Alport Syndrome, Nephritis	Altered Intercellular Communication	The present study evaluates the role of Discoidin Domain Receptor 1 (DDR1) in cell-matrix interaction involved in pathogenesis of Alport syndrome including renal inflammation and fibrosis.	20307660
Renal fibrosis, Inflammation, Hereditary	Altered Intercellular Communication	Loss of DDR1-expression in the kidney delayed renal fibrosis and inflammation in hereditary type IV collagen disease.	20307660
Disturbance, Inflammation	Altered Intercellular Communication	In addition, markers of immune disturbance, inflammation and disease activity using the European League Against Rheumatism SS Disease Activity Index were analysed in patients.	20308122
Osteomyelitis, Inflammation, Fracture, Degenerative polyarthritis	Altered Intercellular Communication	Of 15 lesions initially classified as osteomyelitis, four were diagnosed as osteoarthritis, four as fracture, and one as inflammation of the soft tissue only.	20308478
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation is believed to play a role in Alzheimer's disease (AD).	20308780
Neoplasms, Ulcer	Altered Intercellular Communication	The most common causes are inflammations, ulcers, neoplasms and angiodysplasias.	20309807
Inflammation, Primary malignant neoplasm, Chronic disease, Cardiovascular Diseases	Altered Intercellular Communication	Oxidative stress and inflammation have been linked to many chronic diseases including cancer and cardiovascular diseases.	20332256
Infection by Trichuris trichiura, Inflammation	Altered Intercellular Communication	Among the patients with T. trichiura infection, colonoscopy showed several erosions in 2 patients (8.3%) and non-specific inflammation of the affected segment of the colon in 3 patients (12.5%).	20333290
physiopathological	Altered Intercellular Communication	Since ICUAP has been associated with female gender in some studies, we hypothesized that hormonal dysfunction might contribute to ICUAP.	20333354
Inflammation, Colorectal Carcinoma, Adenoma of large intestine	Altered Intercellular Communication	Chronic inflammation, which is suspected to play a role in the development of colorectal cancer (CRC), has rarely been studied in colorectal adenoma.	20333461
Inflammation	Altered Intercellular Communication	Although oxidative damage and inflammation have been theorized to affect RDW, the relationships of antioxidants and inflammation with RDW have not been well characterized.	20334961
Corneal ectasia	Altered Intercellular Communication	Pregnancy could prompt hormonal changes, which in turn could affect the biomechanical stability of the cornea, leading to corneal ectasia.	20335804
Inflammatory abnormality of the eye, Re-Epithelialization	Altered Intercellular Communication	Weeks after instituting systemic immunosuppressive medications, including corticosteroids and cyclophosphamide, the ocular inflammation gradually resolved with corneal re-epithelialization and severe stromal neovascularization.	20335808
Inflammation, Necrosis	Altered Intercellular Communication	The pathogenesis of surgically induced scleral necrosis not associated with autoimmune conditions may be the result of the products of inflammation and lytic enzymes released by the surrounding conjunctival tissue initiating the scleral melting process.	20335810
Inflammation, Injury of bile duct	Altered Intercellular Communication	This technique is recommended as an attractive solution to prevent bile duct injury, particularly when severe inflammation is associated to extrahepatic anatomic variants of the biliary tree.	20336321
Pain Distress Question, Sore to touch, Appendicitis, CTCAE, Inflammation	Altered Intercellular Communication	We defined equivocal appendicitis as a right lower quadrant pain with tenderness and an apppendiceal diameter of 6 to 9 mm without appendicolith or severe adjacent inflammation as radiological findings.	20336903
Inflammation	Altered Intercellular Communication	Serum metalloproteinase leukolysin (MMP-25/MT-6): a potential metabolic marker for atopy-associated inflammation.	20337648
Chronic Obstructive Airway Disease	Altered Intercellular Communication	Leukolysin is a novel matrix metalloproteinase (MMP-25/MT-6) released mainly by granulocytic cells, primarily neutrophils, which are implicated in chronic airways inflammation.	20337648
ARCN1 gene, Chronic Obstructive Airway Disease, Asthma	Altered Intercellular Communication	Among individuals with history of chronic airways inflammation (asthma and COPD) serum leukolysin may be a metabolic marker associated with chronic atopy-associated respiratory inflammation.	20337648
Inflammation	Altered Intercellular Communication	Myeloid-related protein (MRP8/14) and its subunits are biomarkers of inflammation.	20337885
Bronchiolitis, Wheezing, Neutrophilia (finding), Asthma, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The mechanism by which an early, severe case of bronchiolitis can result in the development of recurrent childhood wheeze or asthma is unclear; however, mucosal inflammation and pulmonary neutrophilia are believed to play a significant role.	20337964
Communicable Diseases, Inflammation	Altered Intercellular Communication	This case emphasizes how important it is for patients after a median sternotomy to receive adequate analgesic and physiotherapeutic support in order to avoid chronic inflammation and infection of the lungs.	20338366
Cryoglobulinemic vasculitis, Inflammation, Hepatitis C, Neuropathy	Altered Intercellular Communication	In cryoglobulinemic vasculitis with hepatitis C, the severity of the neuropathy depends on the nature of the cellular inflammation and the size of the vessel involvement.	20338607
Inflammation, Saint Lucia	Altered Intercellular Communication	The inflammation was diagnosed in 72.5% of OC and 41.5% of LC patients.	20339988
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Increased risk of colorectal cancer among patients with biliary tract inflammation: a 5-year follow-up study.	20340129
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The purpose of the study was to investigate the risk of colorectal cancer among patients with biliary tract inflammation (BTI) compared to non-BTI patients during a 5-year follow-up period.	20340129
Colorectal Carcinoma, Cholangitis	Altered Intercellular Communication	We also found that the adjusted hazard ratio for colorectal cancer for those with bile duct inflammation was 3.30 times (95% CI = 1.87-5.84) as high as for those without BTI within the 5-year follow-up period.	20340129
Cholecystitis, Colorectal Carcinoma	Altered Intercellular Communication	However, no increased hazard of colorectal cancer was observed for patients with gallbladder inflammation.	20340129
Inflammation, Sore to touch	Altered Intercellular Communication	Noted on presentation were bite marks on the right middle toe with minimal inflammation and tenderness.	20345298
Inflammation, Neoplasms, Gout	Altered Intercellular Communication	The tumor was ultimately found to be secondary to gouty inflammation of the pes anserine bursa, a previously unrecognized manifestation of acute gout.	20345364
Acute Kidney Injury, CTCAE, Inflammation, Malnutrition, Crush syndrome	Altered Intercellular Communication	Malnutrition and inflammation in acute kidney injury due to earthquake-related crush syndrome.	20346168
Acute Kidney Injury, CTCAE, Inflammation, Malnutrition, Kidney Failure, Acute	Altered Intercellular Communication	Malnutrition and inflammation are common and serious complications in patients with acute kidney injury (AKI).	20346168
Inflammation, Malnutrition, Kidney Failure, Acute	Altered Intercellular Communication	This study describes the clinical characteristics of malnutrition and inflammation in patients with AKI and CS due to the Wenchuan earthquake.	20346168
Inflammation, Malnutrition	Altered Intercellular Communication	Malnutrition and inflammation was common in patients with earthquake-related CS and had a negative impact on the prognosis of these subjects.	20346168
Crush syndrome, Inflammation, Malnutrition	Altered Intercellular Communication	The results of this study indicate that the use of RRT, intensive nutritional supplementation and transfusion alleviated the degree of malnutrition and inflammation in hemodialysis patients with crush syndrome.	20346168
Inflammation, Hydrarthrosis, Knee joint, Gout	Altered Intercellular Communication	Fifty-one (25.5%) knee joints were found clinically involved, while at least one US finding indicative of joint inflammation was obtained in 73 (36.5%) knee joints.The most frequent US finding indicative of knee joint inflammation was joint effusion, detected in 21 (35%) out of 60 knees and in 52 (37%) out of 140 knees, in gout and CPPD disease, respectively.	20346230
Inflammation	Altered Intercellular Communication	Resistin was associated with laboratory markers of inflammation.	20346233
Refractory anemias, Inflammation	Altered Intercellular Communication	Positive correlation between levels of visfatin and resistin may suggest that visfatin plays a role in inflammation in RA.	20346233
Inflammation, Rheumatoid Arthritis, Metabolic Syndrome X	Altered Intercellular Communication	Visfatin is not associated with inflammation or metabolic syndrome in patients with severe rheumatoid arthritis undergoing anti-TNF-alpha therapy.	20346239
Refractory anemias, Inflammation, Atherosclerosis	Altered Intercellular Communication	Chronic systemic inflammation is of major importance in the development of atherosclerosis in RA.	20346239
Inflammation	Altered Intercellular Communication	However, it remains unclear whether such abnormalities result from systemic inflammation or from abnormalities at stem cell level.	20346245
Refractory anemias, Inflammation	Altered Intercellular Communication	The results suggest that the enhanced expression of FKBP5 in BM CD34+ cells might be an intrinsic abnormality of RA BM CD34+ cells, whereas the enhanced expression of AREG and CXCR4 in BM mononuclear cells might be secondary to systemic inflammation.	20346245
Inflammation, Chronic heart failure	Altered Intercellular Communication	Relation of left ventricular ejection fraction and functional capacity with metabolism and inflammation in chronic heart failure with reduced ejection fraction (from the MIMICA Study).	20346316
Inflammation, Heart failure	Altered Intercellular Communication	Catabolism and inflammation play a role in the physiopathology of heart failure with reduced ejection fraction and are more pronounced in the advanced stages of the disease.	20346316
Pain Distress Question, Cystitis	Altered Intercellular Communication	Cannabinoid receptor agonists have been shown to modulate urinary bladder contractility and reduce pain after bladder inflammation; their clinical efficacy on lower urinary tract symptoms was demonstrated in the Cannabinoids in Multiple Sclerosis study.	20346490
Cessation of life, Diabetes Mellitus	Altered Intercellular Communication	Markers of malnutrition-inflammation (albumin, hemoglobin, and white blood cell values) or the presence of diabetes did not influence the relation between glycemic control and death (all P for interaction > 0.2).	20346561
Inflammation, Heart failure	Altered Intercellular Communication	Neurohormonal activation and inflammation characterizes heart failure, relates to outcome, and is a therapeutic target.	20346637
Inflammation, atherosclerotic, diabetic	Altered Intercellular Communication	Enhanced tyrosine nitration of prostacyclin synthase is associated with increased inflammation in atherosclerotic carotid arteries from type 2 diabetic patients.	20348234
Atherosclerosis, Diabetes Mellitus, vascular inflammations, Diabetes Mellitus, Non-Insulin-Dependent, atherosclerotic	Altered Intercellular Communication	These data demonstrate that diabetes preferentially increases PGIS nitration that is associated with excessive vascular inflammation in atherosclerotic carotid arteries from patients with type 2 diabetes, suggesting a possible role of tyrosine nitration of PGIS in the development of atherosclerosis in patients with diabetes.	20348234
Inflammation	Altered Intercellular Communication	Human intestinal ischemia-reperfusion-induced inflammation characterized: experiences from a new translational model.	20348235
Inflammation	Altered Intercellular Communication	Although intestinal IR-induced inflammation has been studied extensively in animal models, human intestinal IR induced inflammatory responses remain to be characterized.	20348235
Inflammation	Altered Intercellular Communication	Markers of inflammation and oxidative stress in peritoneal dialysis: a comparison between high and low peritoneal transporters.	20349414
Inflammation	Altered Intercellular Communication	It has been hypothesized that this might be a result of a state of chronic inflammation and increased oxidative stress.	20349414
Uremia, Inflammation, Malnutrition, Immune System Diseases	Altered Intercellular Communication	Neutrophils in uremia maintain chronic inflammation, which contributes to malnutrition and immunity disorders.	20349422
COLLAGENOSIS, FAMILIAL REACTIVE PERFORATING, polychondritis, Inflammation, Collagen Diseases	Altered Intercellular Communication	Relapsing polychondritis (RPC) is a rare rheumatic disease characterized by recurrent inflammation of cartilaginous structures, with airway involvement a major cause of morbidity and mortality.	20350245
Inflammatory Bowel Diseases, Crohn Disease, Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Deficiency in 1alpha,25-dihydroxyvitamin D(3) (1,25D(3)) has been suggested as an important environmental factor for immuno-mediated disorders including inflammatory bowel diseases (IBD), comprising Crohn's disease and ulcerative colitis, both characterized by chronic intestinal inflammation.	20350569
Inflammation	Altered Intercellular Communication	Whether inflammation, an outcome predictor in dialysis patients, plays a role is unknown.	20350963
Inflammation, Uremic pruritus	Altered Intercellular Communication	Inflammation may bridge uremic pruritus to high mortality, and elevated hs-CRP predicts a worse outcome in this population.	20350963
Inflammation, Vascular Diseases	Altered Intercellular Communication	C-reactive protein is a marker of inflammation and vascular disease.	20350977
Inflammation	Altered Intercellular Communication	These data suggest that low-grade inflammation as assessed by high-sensitivity C-reactive protein is associated with cerebral microstructural disintegration that predominantly affects frontal pathways and corresponding executive function.	20350977
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The lesions formed masses with an infiltrative pattern and all had 3 key histologic features: fibrosis, chronic inflammation, and fat necrosis-without a known etiology.	20351487
Inflammation, Hyperemia	Altered Intercellular Communication	There were no significant differences in endoscopic hyperemia and histological inflammation among the groups (P>0.05).	20352149
Cerebrovascular Disorders, Inflammation, Thrombosis	Altered Intercellular Communication	Inflammation and thrombosis, two processes influencing each other, are involved in the pathogenesis of cerebrovascular disease.	20352160
Inflammation, Cerebral Ischemia	Altered Intercellular Communication	These results indicate that monocytes activated by inflammation rather than platelets might be the candidates to initiate platelet-monocyte rosetting during the pathogenesis of atherothrombotic cerebral ischaemia and that haemostasis might be activated secondarily by the first occurring inflammation.	20352160
Inflammation	Altered Intercellular Communication	Surgical removal and histopathology showed evidence of severe chronic sterile inflammation and no malignant cell.	20352220
Lymphocyte count increased, Lymphocytic Choriomeningitis, Esophagitis	Altered Intercellular Communication	Lymphocytic esophagitis (LE), a new entity characterized by peripapillary lymphocytosis, questions the role lymphocytes play in esophageal inflammation.	20353445
Refractory anemias, Pain Distress Question, Inflammation, Fatigue	Altered Intercellular Communication	Fatigue in RA was related to pain and functioning, not inflammation, as disease-related factors and to several psychosocial factors including coping and cognitions concerning fatigue.	20353956
Hay fever	Altered Intercellular Communication	Alpha-melanocyte-stimulating hormone plays an important role in the onset of pollinosis in a pollen allergy mouse model.	20357480
Airway structure, Asthma	Altered Intercellular Communication	Exhaled breath temperature (EBT) has been suggested as a non-invasive surrogate marker of airway inflammation in asthma.	20357487
Airway structure, Exacerbation of asthma	Altered Intercellular Communication	Changes in airway inflammation during virus-induced asthma exacerbations are reflected in EBT changes.	20357487
Airway structure	Altered Intercellular Communication	These preliminary data suggest a possible role of EBT measurements in the assessment of airway inflammation in children with virus-induced asthma.	20357487
Colitis, Non-necrotizing granulomatous inflammation, Diverticular Diseases, Deficiency of butyryl-CoA dehydrogenase, Inflammatory disorder, Diverticular disease of colon	Altered Intercellular Communication	Segmental colitis associated with diverticular disease (SCAD) is a colonic inflammatory disorder with localized non-granulomatous inflammation at sigmoid colon, and associated with colonic diverticulosis.	20357530
nervous system disorder, Inflammation, Primary malignant neoplasm, Chronic disease	Altered Intercellular Communication	Oxidative stress is involved in the pathogenesis of many chronic disorders including cancer, inflammation, and neurologic diseases.	20357718
Inflammation, Primary malignant neoplasm, Osteomyelitis, Crohn Disease, Chronic gastritis	Altered Intercellular Communication	Cancer can arise in areas of chronic inflammation such as osteomyelitis with a draining sinus, Crohn's disease, or chronic gastritis.	20359562
Weight Gain, Inflammation	Altered Intercellular Communication	This suggests that inflammation plays a key role in the process of weight gain, especially after smoking cessation.	20360759
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Fibrosis, lobular inflammation, ballooning and steatosis were evaluated (Brunt system).	20361076
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	In the univariate analysis, LS was correlated with fibrosis (r=0.661; p<0.0001), steatosis (r=0.435, p<0.0001), ballooning (r=0.385; p=0.001) and lobular inflammation (r=0.364; p=0.002).	20361076
Inflammation, Fatty degeneration, Liver Stiffness	Altered Intercellular Communication	Steatosis, ballooning and inflammation do not influence liver stiffness.	20361076
Inflammation, Ulceration, CTCAE, Stenosis	Altered Intercellular Communication	One case in particular is, to our knowledge, the first report of the natural history of this clinical entity, initially presenting with the acute picture of inflammation and ulceration with subsequent progression to the more chronic development of diaphragm-like fibrous strictures.	20361083
Inflammation	Altered Intercellular Communication	An intriguing finding was the absence of chronic inflammation in partial atrophy foci as well as in areas of mergence between these lesions.	20361207
Inflammation, Atrophic	Altered Intercellular Communication	Inflammation was present only in isolated complete focal atrophy foci.	20361207
Tissue damage, Inflammation, Atrophic, Ischemia	Altered Intercellular Communication	The question of whether the inflammation produces tissue damage and prostatic atrophy or whether some other insults like ischemia induces the tissue damage and atrophy directly, with inflammation occurring secondarily, is still unsettled.	20361207
Inflammation	Altered Intercellular Communication	The absence of severe toxoplasmic foetopathy, the very exaggerated and atypical placental inflammation and the immune restoration context led to the diagnosis of placental IRIS associated with Toxoplasma gondii reactivation.	20361998
Inflammation, Aortic valve disorder	Altered Intercellular Communication	Prior studies suggest that the causes of calcific aortic valve (AV) disease involve chronic inflammation, lipoprotein levels, and calcium metabolism, all of which may differ among race-ethnic groups.	20362732
Inflammation	Altered Intercellular Communication	Low fluidic parameters led to a lower increase in CCT 1 day and 7 days postoperatively, decreased anterior segment inflammation at 1 day, and yielded clear corneas.	20362850
Inflammation	Altered Intercellular Communication	In asthma hyperresponsiveness to adenosine (AMP) is more closely related to inflammation than to methacholine (MCh).	20363117
Inflammation, Overweight	Altered Intercellular Communication	Overweight asthmatic women have more pronounced systemic inflammation, but are less responsive to MCh.	20363117
Airway structure, Overweight	Altered Intercellular Communication	Our findings suggest that overweight asthmatic women do not feature increased airway inflammation, but do represent a distinct phenotype as compared to normal weight patients.	20363117
Pneumonitis	Altered Intercellular Communication	Loss of negative feedback control of nuclear factor-kappaB2 activity in lymphocytes leads to fatal lung inflammation.	20363924
Alveolar damage, Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	Here we show that mice deficient in p100 but with constitutive expression of p52 in lymphocytes developed fatal lung inflammation characterized by diffuse alveolar damage with marked peribronchial fibrosis.	20363924
Pneumonitis	Altered Intercellular Communication	In contrast, their littermates with only p100 deficiency or constitutive expression of p52 in lymphocytes developed mild lung inflammation with perivascular lymphocyte infiltration and had a normal life span.	20363924
Pneumonitis	Altered Intercellular Communication	The fatal lung inflammation is associated with high-level induction of interferon-gamma and its inducible inflammatory chemokines, suggesting the involvement of a T-helper-1 immune response.	20363924
Inflammation, Congestive heart failure	Altered Intercellular Communication	Our aim was to define the distribution of monocyte subsets in a cohort of congestive heart failure (CHF) patients, to verify whether increased severity of CHF is linked to the expansion of specific monocyte subsets, and finally to investigate the relationship between monocyte subset relative frequencies, laboratory parameters of inflammation, and monocyte ACE expression.	20364047
Inflammation, Electrocardiogram: myocardial infarction (finding), atherosclerotic	Altered Intercellular Communication	Vascular endothelial growth factor (VEGF) is a potent angiogenic growth factor that has been shown to play a significant role in neovascularization during inflammation in atherosclerotic plaques, formation of collateral vessels to an area of ischemic myocardium and neovascularization at the edges of a myocardial infarction during its repair.	20364398
Airway structure, Allergic, Asthma, Bronchial Hyperreactivity	Altered Intercellular Communication	Although much is known about the fact that IgE-mediated allergic inflammatory response contributes to airway inflammation, bronchial hyperresponsiveness, and asthma severity, little is known about the degree of IgE response in allergic asthmatics during treatment.	20364560
Inflammation, Atherosclerosis	Altered Intercellular Communication	Malnutrition-inflammation score associated with atherosclerosis, inflammation and short-term outcome in hemodialysis patients.	20364569
Inflammation, Malnutrition	Altered Intercellular Communication	Malnutrition-Inflammation Score (MIS) has been proposed as a new quantitative system for assessment of malnutrition and inflammation, which are common important risk factors for increased morbidity and mortality in maintenance hemodialysis (MHD) patients.	20364569
Inflammation, Saint Lucia	Altered Intercellular Communication	Inflammation was diagnosed in 55.6% of OC patients and 36.0% of LC patients.	20367813
Inflammation	Altered Intercellular Communication	Diagnosis of inflammation, presence of co-morbidities and BDD each had a significant impact on LOS and TC.	20367813
Hyperuricemia	Altered Intercellular Communication	In T2DM males, hyperuricaemia is associated with raised neurohormones together with better beta-cell indices.	20368210
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Hypovitaminosis D in Chinese type 2 diabetes: lack of impact on clinical metabolic status and biomarkers of cellular inflammation.	20368211
Inflammation, Atherosclerosis	Altered Intercellular Communication	The chemokine monocyte chemoattractant protein-1 (MCP-1) is implicated in chronic inflammation, insulin resistance and atherosclerosis.	20368224
Inflammation	Altered Intercellular Communication	Regular exercise may improve systemic markers of chronic inflammation, but direct evidence and dose-response information is lacking.	20368384
Inflammation, Pancreatitis, Failure, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	One of the proposed mechanisms of beta cell failure is local inflammation, but the presence of pancreatic islet inflammation in type 2 diabetes and the mechanisms involved remain under debate.	20369226
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Saturated-fatty-acid-induced NF-kappaB activation and endoplasmic reticulum stress may contribute to IL-1beta production and mild islet inflammation in type 2 diabetes.	20369226
Acromegaly, Endocrine System Diseases	Altered Intercellular Communication	Acromegaly is a chronic endocrinopathy characterized by hypersecretion of growth hormone (GH) and consequently of insulin-like growth factor-1 (IGF-1).	20369240
Inflammation, Hyperplasia, Hypertrophy	Altered Intercellular Communication	The pancreas displayed inflammation foci, hypertrophy and hyperplasia of the islets of Langerhans.	20369585
Dyspnea, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	[The role of altered respiratory mechanics and systemic inflammation in the development of dyspnea in patients with chronic obstructive pulmonary disease].	20369611
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation resolved with a course of doxycyline and oral steroids.	20370334
HD Term Type, Inflammation	Altered Intercellular Communication	Chronic inflammation and oxidative stress are prevalent in hemodialysis (HD) patients.	20370442
Inflammation	Altered Intercellular Communication	Pioglitazone can decrease urinary albumin and MCP-1 excretion in type 2 diabetics, which may partly contribute to its reno-protection by inhibiting the inflammation reaction in vivo.	20371128
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The inflammation grade and fibrosis stage were assessed according to Ishak.	20371429
Inflammation, Necrotizing fasciitis, Necrosis	Altered Intercellular Communication	Necrotizing fasciitis (NF) is a rare, life-threatening soft-tissue infection, characterized by rapidly spreading inflammation, with secondary necrosis of the fascia and surrounding tissues.	20371436
Inflammation, Heart failure	Altered Intercellular Communication	Glucocorticoid receptor gene, low-grade inflammation, and heart failure: the Heart and Soul study.	20371666
Inflammation	Altered Intercellular Communication	The pathological report indicated chronic inflammation with heavy plasma cell infiltration on the specimen.	20372941
Communicable Diseases, Peptic Ulcer, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Infection with the partial cagPAI strains was less likely to be associated with peptic ulcer and chronic gastric mucosal inflammation than infection with strains possessing intact cagPAI.	20372956
Inflammation, Urolithiasis	Altered Intercellular Communication	Further diagnoses were BPH (30%), inflammation (10%), urolithiasis (7%), and"further conditions" (16%).	20373094
Inflammation	Altered Intercellular Communication	Markers of platelet mediated inflammation showed increasing (CD40 ligand) and decreasing (P-selectin) levels after PCI.	20373128
Inflammation, Dental Plaque, Rupture, Atherosclerosis	Altered Intercellular Communication	Accumulating evidence suggests that inflammation as well as oxidative stress play essential roles in atherogenesis, progression of atherosclerosis, and plaque instability and rupture.	20374186
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Obesity-related chronic inflammation is implicated in the pathogenesis of type 2 diabetes (T2D).	20375213
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	The role of immune cells in the chronic inflammation of obesity and T2D requires further investigation.	20375213
Inflammation, Anemia	Altered Intercellular Communication	On D16, low plasma albumin increased, anemia improved, and high levels of inflammation markers declined.	20375421
Nasal inflammation	Altered Intercellular Communication	Her nasal inflammation progressed despite trials of prednisone, methotrexate, and azathioprine.	20375822
Granulomatous inflammation	Altered Intercellular Communication	A septal perforation developed and a repeat biopsy showed granulomatous inflammation.	20375822
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Inflammation and incident-isolated systolic hypertension in older adults: the Rotterdam study.	20375909
Inflammation, Biliary calculi	Altered Intercellular Communication	Ultrasound showed gallstones without inflammation of the gallbladder.	20375939
Inflammation, Psoriasis, Dermatitis, Atopic, Dermatologic disorders, Data types - Address	Altered Intercellular Communication	Atopic dermatitis (AD) and psoriasis are common skin diseases characterized by cutaneous inflammation and disturbed epidermal differentiation.	20376060
Inflammation, Thrombus, Coronary Artery Disease, Thrombophilia	Altered Intercellular Communication	Hypercoagulability, platelet function, inflammation and coronary artery disease acuity: results of the Thrombotic RIsk Progression (TRIP) study.	20377327
Inflammation, Coronary Artery Disease, Thrombophilia	Altered Intercellular Communication	The objective of the study was to determine the relation of platelet reactivity, hypercoagulability and inflammation in various stages of coronary artery disease acuity (CAD).	20377327
Inflammation, Thrombophilia, Cardiovascular Diseases	Altered Intercellular Communication	A distinct pathophysiological state of heightened platelet function, hypercoagulability and inflammation marks the presence of unstable cardiovascular disease requiring intervention.	20377327
Inflammation, Atherosclerosis	Altered Intercellular Communication	Chronic inflammation due to antigen-specific responses is an important factor in the acceleration of atherosclerosis.	20377769
Rheumatoid Arthritis, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Long-term anti-TNF-alpha treatments reverse the endothelial dysfunction in rheumatoid arthritis: the biological coherence between synovial and endothelial inflammation.	20378011
Refractory anemias, Rheumatoid Arthritis, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Rheumatoid arthritis (RA) is associated with an excess cardiovascular morbidity and mortality, related to systemic inflammation with endothelial dysfunction (ED) and impaired flow-mediated vasodilation (FMD).	20378011
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	Is there a link between inflammation and abnormal lipoprotein profile in Sjogren's syndrome?	20378384
Sjogrens Syndrome", Inflammation, PEELING SKIN SYNDROME	Altered Intercellular Communication	To investigate the lipoprotein profile of patients with primary Sjogren's syndrome (pSS) and its association with laboratory tests, including markers of inflammation.	20378384
Inflammation, Dyslipidemias, PEELING SKIN SYNDROME	Altered Intercellular Communication	The presence of dyslipidemia in pSS was associated with increased ESR (44.05+/-28.07 versus 28.28+/-18.00, P=0.03), but not with other laboratory markers of the disease and inflammation.	20378384
vascular inflammations	Altered Intercellular Communication	Angiopoietin-1 is a vascular strengthening factor during vascular development and a protective factor for pathological vascular inflammation and leakage.	20378606
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Brain vascular leaking and inflammation are two important pathological processes of stroke; therefore, we hypothesized that variants of the microRNA-binding site in angiopoietin-1 would affect its expression and confer a risk of stroke.	20378606
Inflammation, Hypertension, CTCAE, physiopathological	Altered Intercellular Communication	Emerging evidence suggests a role for resistin in inflammation and vascular dysfunction, which may contribute to the pathogenesis of hypertension, but the association between resistin levels and incident hypertension is unknown.	20378819
Malnutrition, Dyslipidemias	Altered Intercellular Communication	Serum beta(2)-microglobulin was associated with longer duration on hemodialysis, malnutrition inflammation (lower serum albumin and higher high-sensitivity C-reactive protein) and dyslipidemia.	20379193
Xanthogranulomatous inflammation, Xanthogranulomatous cholecystitis	Altered Intercellular Communication	Macroscopic and microscopic findings revealed xanthogranulomatous inflammation, which led to a diagnosis of xanthogranulomatous pancreatitis.	20382597
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Immune system cells are important modulators of chronic inflammation in diabetes mellitus, but the role of B cells is not adequately studied.	20383694
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Altered TLR function in B cells from diabetes mellitus patients increases inflammation by two mechanisms: elevation of pro-inflammatory IL-8 and lack of anti-inflammatory/protective IL-10 production.	20383694
Granulomatous inflammation	Altered Intercellular Communication	Biopsies of oral mucosa (gingiva, buccal) exhibited in one case granulomatous inflammation, and in both cases, thick irregular clumps of tortuous, red-staining abnormal elastic fibers.	20384464
Macular Edema, Cystoid, Acute inflammation	Altered Intercellular Communication	In spite of the greater theoretical risk of increased postoperative inflammation following MSICS, there was no evidence of cystoid macular oedema, either clinically or on OCT.	20384591
Inflammation	Altered Intercellular Communication	This study reveals that HLA-DR expression is modulated differently on CD14HIGH (classical) versus CD14LOW (inflammatory) monocytes after systemic inflammation.	20385017
Overgrowth, Inflammation, Lower Urinary Tract Symptoms, Benign prostatic hypertrophy	Altered Intercellular Communication	Chronic inflammation is now considered a determinant of benign prostatic hyperplasia (BPH), promoting, together with the hormonal milieu, prostate overgrowth and lower urinary tract symptoms (LUTS).	20386089
Overgrowth, Inflammation, Lower Urinary Tract Symptoms, Benign prostatic hypertrophy	Altered Intercellular Communication	Chronic inflammation is now considered a determinant of benign prostatic hyperplasia (BPH), promoting, together with the hormonal milieu, prostate overgrowth and lower urinary tract symptoms (LUTS).	20386089
Inflammation, Hyperoxia	Altered Intercellular Communication	Herein, we determined the contribution of mechanical ventilation, hyperoxia and inflammation, individually or combined, to the cytokine/chemokine response of the neonatal lung.	20386489
Inflammation	Altered Intercellular Communication	Depending on the individual cytokine or chemokine, the combination of both oxygen and inflammation intensifies or abrogates the low VT-induced inflammatory response.	20386489
Inflammation, Hypoxia, Diabetes Mellitus, Non-Insulin-Dependent, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	Because mitochondrial dysfunction, inflammation, endoplasmic-reticulum stress and hypoxia all inactivate mTORC1, our results may suggest a unifying mechanism for the pathogenesis of insulin resistance in T2D, although the underlying causes might differ.	20386866
Degenerative polyarthritis, Pain Distress Question, Inflammation	Altered Intercellular Communication	Aceclofenac, a NSAID is widely used in the treatment of pain and inflammation associated with osteoarthritis.	20387351
Inflammation, Stenosis, Traumatic injury, Hypospadias	Altered Intercellular Communication	Three of the strictures were due to trauma, one was due to inflammation, and one was due to a failed hypospadia repair.	20387514
Chronic lymphocytic inflammation, Malignant Neoplasms	Altered Intercellular Communication	Histological examination of a pleural biopsy specimen obtained by thoracoscopy showed chronic lymphocytic inflammation, but no malignancy.	20387528
Inflammation, Inflammatory edema	Altered Intercellular Communication	The paper describes a case of disseminated intestinal and cutaneous thromboangiitis (Kohlmeier-Degos' syndrome) in a 32-year-old female patient who has died from intoxication due to severely impaired permeability of the epithelial barrier mainly of the large bowel (diphtheritic inflammation of the mucosa, severe inflammatory edema of the submucous layer, and fibrinous impregnation of the serous membrane).	20387678
Inflammation, Fibrosis Assessment, Stenosis Morphology, Ulcer, Foot-and-Mouth Disease, Intestines, Small	Altered Intercellular Communication	More than three ulcerations (aphthous lesions or ulcers) or the presence of stenosis caused by inflammation or fibrosis was diagnostic of small bowel CD.	20388061
Inflammation, Carcinogenesis	Altered Intercellular Communication	It is noteworthy the potential association of common SNPs in pro-inflammatory genes with PC risk, since chronic inflammation is assumed to play a key role in prostate carcinogenesis.	20388081
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Inflammation and ECM (extracellular matrix) remodelling play important roles in LV (left ventricular) remodelling following acute MI (myocardial infarction).	20388121
Inflammation	Altered Intercellular Communication	PBMCs also contribute to systemic and regional inflammation and matrix remodelling in acute MI.	20388121
Vanishing bile duct syndrome, Necrosis with inflammation	Altered Intercellular Communication	The main pathological changes of CR were the vanishing bile duct syndrome and obliterative arteriopathy;and the early stage of CR were the damage of inter lobular bile duct, necrotic inflammation in central lobule, and inflammatory cells infiltration in portal area.	20388439
HD Term Type, Inflammation	Altered Intercellular Communication	Chronic inflammation in haemodialysis (HD) patients indicates a poor prognosis.	20388631
Inflammation, Cholestasis, Bile duct structure	Altered Intercellular Communication	Liver biopsy revealed portal inflammation, severe bile duct loss, and cholestasis.	20388938
Communicable Diseases, Inflammation	Altered Intercellular Communication	These findings suggest that H. pylori does not influence antioxidants bioavailability in its asymptomatic stages of infection until a factor or combination of factors triggers the inflammation cascade which may lead to increased oxidative stress and possibly reduced bioavailability of vitamins E and C.	20389061
Inflammation, Cavitation (process), Edema	Altered Intercellular Communication	MRI showed inflammation and edema in the area of the thalamus and internal capsule in the early stage, then cavitation and gliosis in the same regions in the late stage.	20389171
Inflammation, Necrosis	Altered Intercellular Communication	Biopsy specimen from the mass showed inflammation and necrotic debris.	20389181
Crohn Disease, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The purpose of this work was to determine in colon mucosa of Crohn's disease (CD) and ulcerative colitis (UC) in relapse: a) the levels of the chaperonins Hsp60 and Hsp10; b) the quantity of inflammatory cells; and c) if the levels of chaperonins parallel those of inflammation cells.	20390473
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Cells typical of inflammation were significantly more abundant in CD and UC than in NC.	20390473
Inflammation	Altered Intercellular Communication	Since chaperonins are key factors in the activation of the immune system leading to inflammation, we propose that they play a central role in the pathogenesis of the two diseases, which, consequently, ought to be studied as chaperonopathies.	20390473
Waldenstrom Macroglobulinemia, Systemic disease, Disease	Altered Intercellular Communication	IgG4-related systemic disease, a disorder recognized only recently, can cause lymphoplasmacytic inflammation in the thoracic aorta.	20391477
Kidney Failure, Chronic, Inflammation, Hemochromatosis	Altered Intercellular Communication	Biological levels are increased in end-stage renal disease and during inflammation but suppressed in hemochromatosis.	20391595
Inflammation, Biliary Tract Hemorrhage	Altered Intercellular Communication	Her Pap smear revealed inflammation with a S haematobium egg.	20391981
Bacterial Vaginosis, Inflammation, Candidiasis	Altered Intercellular Communication	Similarly, annual follow-up of Pap smears for the past 13 years showed mild inflammation with bacterial vaginitis and monilial infection.	20391981
Parkinson Disease, Neurodegenerative Disorders, palladium	Altered Intercellular Communication	Parkinson's disease (PD) is a neurodegenerative disorder caused by a disruption of dopaminergic neurotransmission in the basal ganglia.	20392453
Inflammation, Liver damage, Metabolic Syndrome X	Altered Intercellular Communication	Ferritin reflected iron stores and metabolic syndrome components, but not inflammation or liver damage.	20392616
Inflammation	Altered Intercellular Communication	Local production of cytokines within the liver may play a pivotal role in the regulation of pathophysiological processes during inflammation.	20393789
Complete atrioventricular block, Hepatitis	Altered Intercellular Communication	Liver IL-17-producing cell infiltration was positively associated with the grade of liver inflammation in CHB and positively correlated to intrahepatic IL-8 expression (r=0.801, p<0.01) or neutrophil infiltration (r=0.917, p<0.01).	20393789
Liver damage	Altered Intercellular Communication	Inappropriate, excessive, and non-specific Th17 and Th1 effector responses may be involved in the pathogenesis of HBV-associated liver inflammation and hepatocellular damage.	20393789
Granulomatous inflammation	Altered Intercellular Communication	Endoscopic sinus surgery confirmed the CT findings, allowed a biopsy taken, and the histology showed prominent caseating granulomatous inflammation.	20394554
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is known to play an important role in atherosclerosis.	20394901
Inflammation	Altered Intercellular Communication	Positron emission tomography imaging with (18)F-FDG provides a measure of plaque inflammation.	20394901
Inflammatory disorder	Altered Intercellular Communication	Elevation of serum autoantibodies to alpha-enolase (ENO1) is often seen in inflammation diseases.	20395242
vascular inflammations, atherosclerotic	Altered Intercellular Communication	Imaging with (18)F-FDG PET/CT is able to reveal vascular inflammation, and several studies have shown that increased (18)F-FDG uptake in carotid artery plaques can qualify the degree of atherosclerotic inflammation.	20395325
Inflammation	Altered Intercellular Communication	A high oxHDL state may be associated with PEW estimated by GNRI and SGA, particularly concomitant with inflammation in MHD patients.	20395357
Sepsis, Inflammation	Altered Intercellular Communication	Suppressed neutrophil apoptosis, a hallmark of sepsis, perpetuates inflammation and delays resolution.	20395555
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Airway inflammation is a central feature of chronic obstructive pulmonary disease (COPD).	20395558
Inflammation	Altered Intercellular Communication	Selected genes involved in inflammation, oxidative stress, and proteolysis were assessed by focused gene array and real-time polymerase chain reaction.	20395558
Inflammation, septic	Altered Intercellular Communication	ADMA catabolism appears to be activated by inflammation; its increase during the advanced septic phase in surviving patients may suggest an endogenous inhibition of NO synthesis during the full-blown septic phase.	20395894
Granuloma, Inflammation	Altered Intercellular Communication	Pleural biopsy revealed 54.5% granulomatous lesion with or without caseation and another 24.2% shows chronic inflammation.	20395911
Pain Distress Question, Inflammation	Altered Intercellular Communication	Outcome measures were i) patients experience of pain and discomfort post-operatively ii) grade of inflammation post-operatively and iii) visual outcome.	20395917
Chemosis of conjunctiva, Inflammation, Corneal edema, Conjunctival congestion	Altered Intercellular Communication	Post-operative inflammation was assessed by slit lamp considering conjunctival congestion, chemosis, corneal striation, corneal oedema, cells and flare in anterior chamber.	20395917
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Body fat distribution and inflammation among obese older adults with and without metabolic syndrome.	20395951
Adenoma, Non-Functioning Endocrine Neoplasm	Altered Intercellular Communication	Although most AIs are nonfunctioning benign adenomas, a multidisciplinary approach with biochemical and radiological evaluation is needed to characterize these lesions and identify patients who are at high risk for hormonal or malignant evolution.	20396632
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Effect of combination of anticytokine preparations anaferon and artrofoon on immune inflammation in rheumatoid arthritis.	20396720
Inflammation, Appendicitis, CTCAE, Gangrene	Altered Intercellular Communication	The pathology showed negative inflammation in 4 cases (9.3%), suppurative appendicitis in 29 cases (67.4%), gangrenous appendicitis in 8 cases (18.6%), and perforated appendicitis in 2 cases.	20396909
Inflammation, Pain Distress Question	Altered Intercellular Communication	Only one patient required readmission due to pericecal inflammation and pain, and another patient needed a percutaneous drainage of fluid collection.	20396909
Microalbuminuria, Rheumatoid Arthritis, Hypertension, CTCAE, Inflammation	Altered Intercellular Communication	Microalbuminuria in rheumatoid arthritis in the post penicillamine/gold era: association with hypertension, but not therapy or inflammation.	20396921
Microalbuminuria, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Microalbuminuria (MA) has been shown to associate with inflammation and future cardiovascular disease (CVD).	20396921
Inflammation	Altered Intercellular Communication	Of the 3 patients who had not demonstrated restricted diffusion on DWI, 2 did not undergo surgery and the other was found to have only chronic inflammation at surgery.	20397131
Inflammation	Altered Intercellular Communication	The results show that the cyclosporine-induced gingival enlargement of these children is not statistically associated with their age, gender, gingival inflammation, or serum level of cyclosporine (P >0.05).	20397903
Gingival Hyperplasia, Inflammation, Dental Plaque	Altered Intercellular Communication	Children administered cyclosporine after liver transplantation show that gingival enlargement is statistically more related to the plaque index than other factors such as age, gender, gingival inflammation, or the serum level of cyclosporine, which suggests that plaque control plays an important role in eliminating gingival enlargement in children who have undergone liver transplantation.	20397903
Inflammation	Altered Intercellular Communication	A short-term evaluation of Nd:YAG laser as an adjunct to scaling and root planing in the treatment of periodontal inflammation.	20397904
Inflammation, Tegumentary leishmaniasis susceptibility, TRPV6 gene	Altered Intercellular Communication	Skin inflammation plays an important role during the healing of American tegumentary leishmaniasis (ATL), the distribution of cells in active lesions may vary according to disease outcome and parasite antigens in ATL scars have already been shown.	20398229
Inflammation, Coronary Stenosis, Pliability, Endothelial dysfunction	Altered Intercellular Communication	Endothelial dysfunction, reduction of the arterial flexibility as well as increased serum inflammation were associated with mild coronary stenosis.	20398485
Pharyngitis, Anxiety, CTCAE 3.0, Inflammatory disorder of cartilage, Dyspnea, Anti-Arrhythmia Agents, dendritic spine neck	Altered Intercellular Communication	These data led to identification of a persistent respiratory infection-related clinical syndrome, including persistent throat infection, neck spinal lesion, rib cartilage inflammation, symptoms of cardiac depression and dyspnea with or without anxiety.	20398562
ETV3 wt Allele	Altered Intercellular Communication	We measured their level and cellular origin in subjects with MetS and analyzed their associations with 1/anthropometric and biological parameters of MetS, 2/inflammation and oxidative stress markers.	20399083
Vascular Diseases, Chronic inflammation	Altered Intercellular Communication	An important non-traditional risk factor for vascular disease is chronic inflammation.	20399263
Inflammation, Kidney Failure	Altered Intercellular Communication	Subclinical inflammation might be related to cellular senescence mechanisms in leukocytes that are fostered by renal insufficiency.	20399263
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Decreased expression of FcgammaRIIB or non-functional FcgammaRIIB variants are associated with the development of autoimmune tissue inflammation.	20399509
Inflammation, Infected hematoma	Altered Intercellular Communication	On account of the absence of the most constant findings, the pulsation of a soft tissue mass and elevated inflammation blood parameters, we preoperatively assumed an infected haematoma.	20400918
Inflammation, Acute Coronary Syndrome, Coronary heart disease	Altered Intercellular Communication	In recent years, researchers have investigated the relationship between biological markers of inflammation and prognosis in patients who experience acute coronary syndromes; however, the association between plasma fibrinogen and coronary heart disease is still not clear.	20401290
Inflammation, Neoplasms	Altered Intercellular Communication	Further studies are needed to fully understand the changes that may affect knee mechanics after surgery and/or inflammation factors secreted by tumor cells.	20402336
Communicable Diseases, Gastrointestinal symptom, Inflammation	Altered Intercellular Communication	The relationship between infection, gastrointestinal symptoms, and systemic inflammation is poorly understood.	20402811
Stomach Diseases, Inflammation, Gastritis, Infection caused by Helicobacter pylori, Foveolar hyperplasia	Altered Intercellular Communication	H. pylori-infected patients had higher scores for acute and chronic inflammation (P < 0.001) and foveolar hyperplasia (P < 0.005) than non-infected patients, while other parameters for gastritis and gastropathy were similar between infected and non-infected patients.	20403032
Inflammation, Communicable Diseases, Traumatic injury, Leukomalacia, Periventricular, Cessation of life	Altered Intercellular Communication	Infection and inflammation leading to injury or death of pre-oligodendrocytes (preOLs) is one of the principal initiating mechanisms in the pathogenesis of preterm periventricular leukomalacia (PVL).	20403340
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	The association between systemic inflammation and the estimated 10-year risk for coronary artery disease (CAD) according to the Framingham risk score is largely unknown.	20403480
Inflammation, Hyperhomocysteinemia	Altered Intercellular Communication	In conclusion, these findings indicate that low-grade systemic inflammation and hyperhomocysteinemia were present in participants with high 10-year risk for CAD.	20403480
Respiratory Distress Syndrome, Adult, Pneumonitis, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	Acute respiratory distress syndrome (ARDS) is characterized by overwhelming lung inflammation.	20404020
Communicable Diseases, Chikungunya Fever, Inflammation	Altered Intercellular Communication	Persistent chronic inflammation and infection by Chikungunya arthritogenic alphavirus in spite of a robust host immune response.	20404278
HMGCL gene, Inflammation, hepcidin, Anemia	Altered Intercellular Communication	Elevated hepcidin levels result in iron restriction and signs of anemia of chronic inflammation, although hepcidin-independent mechanisms contribute to development of anemia in HL.	20406921
Inflammation, Infection	Altered Intercellular Communication	Inflammation and cytokine patterns produced by T lymphocytes play an important role in susceptibility to infections.	20407285
Inflammation, Organ Dysfunction Scores, Brain Death	Altered Intercellular Communication	In conclusion, the presence of inflammation and apoptosis induction may explain the rapid organ dysfunction seen after brain death.	20407403
Burn Specimen Source Codes, Hypermetabolism, Inflammation	Altered Intercellular Communication	Increased catecholamine (CA) levels after severe burn are associated with stress, inflammation, hypermetabolism, and impaired immune function.	20407405
Gait Disorders, Neurologic, Inflammation, Stanford Cancer Institute, Cervical spinal cord injury	Altered Intercellular Communication	Much of the morbidity and mortality that occurs in patients afflicted with cervical spinal cord injury (SCI) occurs early after injury due to primary neurologic dysfunction, systemic inflammation, concomitant injuries, treatments to prevent and ameliorate secondary insults, and prolonged immobilization.	20407933
Lymphoma, T-Cell, Cutaneous, Inflammation, Psoriasis, Dermatitis	Altered Intercellular Communication	Decreased T-cell Ku70 expression was not a feature of the benign dermatoses psoriasis and contact dermatitis, suggesting that loss of Ku70/80 in CTCL is not simply the result of cutaneous inflammation.	20408834
BDI - Functional Impairment, Anemia, Inflammation, Anemia, Sickle Cell	Altered Intercellular Communication	In conclusion, NT-proBNP elevation is common and is associated with markers of anaemia, inflammation and iron status and with severe functional impairment among sickle cell anaemia patients in Nigeria.	20408845
Inflammation, Meckel Diverticulum, Perforation (observation)	Altered Intercellular Communication	Emergency operation finally confirmed a 12-cm giant Meckel's diverticulum with genuine inflammation and imminent perforation.	20409519
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Plasma concentration of visfatin is a new surrogate marker of systemic inflammation in type 2 diabetic patients.	20409603
Diabetic Nephropathy, Inflammation, diabetic	Altered Intercellular Communication	It is not clear whether plasma visfatin level is related with systemic inflammation or diabetic nephropathy in diabetic patients.	20409603
Inflammation, diabetic	Altered Intercellular Communication	These findings suggest that visfatin synthesis is activated from adipose tissue in a diabetic environment, induces NF-kappaB activation and leads to activation of pro-inflammatory cytokines and systemic inflammation.	20409603
Inflammation	Altered Intercellular Communication	Urinary hepcidin correlated positively with the 2 measured indicators of inflammation (r > or = 0.42, P < 0.01) but not with the 2 indicators of iron nutrition (r < 0.07).	20410090
Inflammation, Neoplasms, Obesity	Altered Intercellular Communication	A number of adipocytokines are increased in obesity causing low-level chronic inflammation associated with an increased risk of tumors.	20410173
Abnormal oral mucosa morphology, Superficial ulcer, Barrett Esophagus, Stenosis, Ulcer	Altered Intercellular Communication	Acid-related damage was defined as any of these findings recorded in CORI: Barrett's esophagus; esophageal inflammation (unless non-acid-related etiology); healed ulcer, duodenal, gastric or esophageal ulcer; stricture; and mucosal abnormality with erosion or ulcer.	20411426
Inflammation	Altered Intercellular Communication	Nuclear factor kB (NF-kB) essential modulator (NEMO) that is required for the activation of NF-kB plays an important role in inflammation.	20412081
Inflammation, Granuloma	Altered Intercellular Communication	The higher frequency of S. aureus colonisation could be a consequence of a recently shown mucosal barrier defect in WG and facilitate chronic inflammation and granuloma formation in the upper respiratory tract.	20412703
Inflammation, Dental Plaque	Altered Intercellular Communication	In this case it was the result of an inappropriate choice of a healing cap, thus allowing an accumulation of dental plaque and sustained chronic inflammation of the peri-implant tissue.	20413199
Inflammation, Atherosclerosis	Altered Intercellular Communication	Although inflammation is an important component of atherosclerosis, it is unknown whether inhaled corticosteroids (ICS) as anti-inflammatory drugs prevent atherosclerosis.	20413534
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Previous studies suggest a relationship between systemic inflammation and body composition in chronic obstructive pulmonary disease (COPD).	20413541
Plaque, Atherosclerotic	Altered Intercellular Communication	Inflammation within carotid atherosclerotic plaque: assessment with late-phase contrast-enhanced US.	20413774
Inflammation, atherosclerotic	Altered Intercellular Communication	This technique has promise as a tissue-specific marker of inflammation and a potential role in the risk stratification of atherosclerotic carotid stenosis.	20413774
Inflammation, Renal function	Altered Intercellular Communication	Further study in younger populations may clarify whether impaired kidney function leads to change in inflammation over time.	20413990
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Intima-media thickness is associated with inflammation and traditional cardiovascular risk factors in non-dialysis-dependent patients with chronic kidney disease.	20413996
Inflammation, Atherosclerosis	Altered Intercellular Communication	Intima-media thickness (IMT) and inflammation are early atherosclerosis markers, although data are lacking about their association in the CKD non-dialysis-dependent (CKD-NDD) population.	20413996
Eye pain, Disorder of the optic nerve, Inflammation	Altered Intercellular Communication	It is reported to emphasize that rapidly progressive severe bilateral optic neuropathy in a young patient with periocular pain need not be caused by inflammation.	20414132
Inflammation, Bronchogenic Carcinoma	Altered Intercellular Communication	In the remaining 3, biopsy revealed no bronchogenic carcinoma (3 patients with inflammation).	20414943
Communicable Diseases, Inflammation, Inflammatory disorder	Altered Intercellular Communication	99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: lifestyle changes affecting the host-environment interface.	20415845
Communicable Diseases, Inflammation, Inflammatory disorder	Altered Intercellular Communication	99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: darwinian medicine and the 'hygiene' or 'old friends' hypothesis.	20415854
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide is a non-invasive marker of airway inflammation and a portable analyser, the NIOX MINO (Aerocrine AB, Solna, Sweden), is now available.	20416092
Granulomatous inflammation, Granuloma	Altered Intercellular Communication	Pathologic examination showed granulomatous inflammation in 16 patients (66.7%), including 10 patients with caseating granulomas.	20417504
Bronchial Hyperreactivity, Thickened, Smooth muscle (tissue), Airway Remodeling, Hypertrophy, Chronic eosinophilic inflammation, Hyperplasia	Altered Intercellular Communication	Chronic eosinophilic inflammation may promote bronchial hyperresponsiveness (BHR), which involves reversible reduction of airflow and airway remodelling such as a thickening of the reticular basement membrane (RBM) and hypertrophy and hyperplasia of airway smooth muscle (ASM).	20418085
Airway structure	Altered Intercellular Communication	BHR to histamine (Hist) and acetylcholine (ACh) cannot differentiate airway inflammation and remodelling.	20418085
Inflammation, Asthma	Altered Intercellular Communication	To examine the correlations between eosinophilic inflammation or airway remodelling and BHR to Hist or ACh in adults with severe asthma.	20418085
Airway structure, Asthma	Altered Intercellular Communication	In adult patients with severe asthma, BHR to ACh is related to the degree of eosinophilic airway inflammation, whereas BHR to Hist indicates airway remodeling, particularly ASM hypertrophy.	20418085
Acute Lung Injury, glycation, Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Plasma was collected from patients with stable IPF, acute exacerbation of IPF, and acute lung injury for measurement of biomarkers of cellular activity/injury (receptor for advanced glycation endproducts, surfactant protein D, KL-6, von Willebrand factor), systemic inflammation (IL-6), and coagulation/fibrinolysis (protein C, thrombomodulin, plasminogen activator inhibitor-1).	20418386
Inflammation, Brain Injuries, COL4A2 wt Allele	Altered Intercellular Communication	These data suggest that inflammation occurs early and persists for several days after ICH in humans and could be involved in the progression of ICH-induced secondary brain damage.	20420814
Multiple Organ Failure, Inflammation, Communicable Diseases, Traumatic injury, Cessation of life	Altered Intercellular Communication	Death after trauma, infection, or other critical illness has been attributed to unbalanced inflammation, in which dysregulation of cytokines leads to multiple organ dysfunction and death.	20421061
Disability, Inflammation, Paresis, Functional Disability	Altered Intercellular Communication	Recent studies have suggested that inflammation may play an important role in aging and the development of disabilities, but knowledge about its importance in the development of muscle weakness and functional disabilities in very old people is limited.	20421241
Inflammation	Altered Intercellular Communication	To examine this, we found two types of responders to cantharidin-induced skin blisters in male healthy volunteers: those with immediate leukocyte accumulation and cytokine/chemokine synthesis followed by early resolution and a second group whose inflammation increased gradually over time followed by delayed resolution.	20421472
Inflammation, Carcinogenesis, Carcinoma of lung	Altered Intercellular Communication	Chronic inflammation could play a role in lung carcinogenesis, underscoring the potential for lung cancer prevention and screening.	20421535
Inflammation, Carcinoma of lung	Altered Intercellular Communication	We investigated the association of circulating high-sensitivity C-reactive protein (CRP, an inflammation biomarker) and CRP single nucleotide polymorphisms (SNPs) with prospective lung cancer risk.	20421535
Carcinogenesis, Carcinoma of lung, Pneumonitis	Altered Intercellular Communication	Elevated CRP levels are associated with subsequently increased lung cancer risk, suggesting an etiologic role for chronic pulmonary inflammation in lung carcinogenesis.	20421535
Presenile dementia, Inflammation, ETV3 wt Allele	Altered Intercellular Communication	However, since inflammation has been suggested among the MetS components, we propose IRBS as an additional feature of the metabolic-cognitive syndrome to also identify a molecular profile in patients at high risk of developing predementia or dementia syndromes.	20421697
Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	The liver biopsies were evaluated and prospectively scored for pathology using 3 independent scoring systems validated for nonalcoholic steatohepatitis and nonalcoholic fatty liver disease [Brunt, NAFLD activity score (NAS) and Dixon methods], whereby numeric values were assigned to degrees of steatosis, inflammation, and fibrosis.	20421811
Inflammation	Altered Intercellular Communication	The Spearman correlation coefficient between the NAS inflammation subscore and serum B12 concentration was 0.02.	20421811
Calgranulin B, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	Calgranulin B is a small calcium-binding protein with several immunological functions mainly involved in chronic inflammation and cancer.	20422274
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD) is a newly recognized high-risk condition for cardiovascular disease (CVD), and previous studies reported the changes in inflammation and oxidative stress in advanced stages of CKD.	20423474
Inflammation	Altered Intercellular Communication	We compared the levels of serum biomarkers for inflammation and oxidative stress between subjects with normal and mildly reduced glomerular filtration rate (GFR).	20423474
Diffuse Axonal Injury, Inflammation, MS gene	Altered Intercellular Communication	It is well documented that disability accumulation in multiple sclerosis is correlated with axonal injury and that the extent of axonal injury is correlated with the degree of inflammation.	20423930
Inflammation, Nerve Degeneration	Altered Intercellular Communication	However, the interdependence between focal inflammation, diffuse inflammation and neurodegeneration, and their relative contribution to clinical deficits, remains ambiguous.	20423930
Inflammation, MS gene	Altered Intercellular Communication	A hypothesis might be that early focal inflammation could be the pivotal event from which all else follows, suggesting the consideration of multiple sclerosis as a two-stage disease.	20423930
Inflammation, Multiple Sclerosis	Altered Intercellular Communication	Our findings demonstrate that multiple sclerosis disability progression follows a two-stage process, with a first stage probably dependent on focal inflammation and a second stage probably independent of current focal inflammation.	20423930
Inflammation, AAVS1 gene, Vasculitis, CTCAE	Altered Intercellular Communication	Osteopontin is a pleiotropic cytokine involved in the recruitment and retention of neutrophils to sites of inflammation, which are the primary targets cells in antineutrophil cytoplasmic autoantibody-associated vasculitis (AAV).	20424002
Inflammation	Altered Intercellular Communication	This study is the first to demonstrate diabetes-specific changes in vitreous lipid autacoids including arachidonate and docosahexanoate-derived metabolites indicating an increase in inflammatory versus anti-inflammatory lipid mediators that correlated with increased levels of inflammatory and angiogenic proteins, further supporting the notion that inflammation plays a role the pathogenesis of this disease.	20424229
Inflammation	Altered Intercellular Communication	It is thus possible for PCNSBL to be histologically misinterpreted as a result of ancillary inflammation, characterized here as a profusion of T cells and macrophages.	20425050
Inflammation, HIV Infections	Altered Intercellular Communication	Inflammation is a hallmark of age-associated comorbidities, and immune activation is a hallmark of HIV disease.	20425052
Coinfection, Inflammation	Altered Intercellular Communication	Constant stimulation of the immune system by HIV or due to co-infections activates the innate and adaptive immune system, resulting in release of mediators of inflammation.	20425052
Accessory breast, Communicable Diseases, Inflammation	Altered Intercellular Communication	In case of polymastia diagnosis is simple; in case of isolated nodule, without local inflammation or infection, there are greater difficulties.	20426920
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Differences in plaque inflammation according to stroke mechanism are an understudied issue.	20427044
thromboembolic, Cerebral Ischemia	Altered Intercellular Communication	The purpose of this pilot study was to compare carotid plaque inflammation in patients with thromboembolic and hemodynamic cerebral ischemia.	20427044
Inflammation, Atherosclerosis	Altered Intercellular Communication	Chronic inflammation and oxidative stress are common risk factors for atherosclerosis.	20427734
Refractory anemias, Rheumatoid Arthritis, Periodontitis	Altered Intercellular Communication	Rheumatoid arthritis (RA) and periodontitis are common chronic inflammatory conditions and share many pathologic features.	20429644
AURKAIP1 gene, Autoimmune Pancreatitis	Altered Intercellular Communication	Autoimmune pancreatitis (AIP) is a chronic inflammatory condition characterized by IgG4-positive plasma cells.	20429758
Sepsis, Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Activation of inflammation and coagulation are closely related and mutually interdependent in sepsis.	20429897
Inflammation, Atherosclerosis	Altered Intercellular Communication	Statins reduce cardiovascular-related morbidity and mortality, but their effects on inflammation in atherosclerosis are not fully understood.	20430391
Asthma, Pneumonitis	Altered Intercellular Communication	Intranasal administration of recombinant rhinovirus proteinase 2A in mice resulted in an increase in airway hyperreactivity, lung inflammation, and IL-4 and IFN-gamma production from CD4 T cells.	20430426
Inflammation, Neoplasms	Altered Intercellular Communication	They are biomarkers of inflammation and indicators of the immune response to tumors.	20430730
Inflammation, Prostatic Neoplasms, Prostate carcinoma	Altered Intercellular Communication	Presence of xenotropic murine leukemia virus-related virus and chronic inflammation in prostate tumor suggests that inflammation plays a role in prostate cancer etiology.	20431935
Crohn Disease, Inflammation, Atherosclerosis	Altered Intercellular Communication	Patients with Crohn's disease might have accelerated atherosclerosis due to: chronic systemic inflammation, metabolic changes or prolonged steroid treatment.	20431949
Cholecystitis, Obesity	Altered Intercellular Communication	Age, obesity, previous surgery, or degree of gallbladder inflammation were not exclusion criteria.	20432208
Inflammation, Gout	Altered Intercellular Communication	Crystals were detected in only 12 samples of synovial fluids, mostly in inflammation and they were all monosodium urate (MUS) so we could diagnose gout.	20432743
Inflammation, Diarrhea	Altered Intercellular Communication	Symptoms range from mild to profuse watery diarrhoea, which may be accompanied by severe life-threatening inflammation of the intestine.	20432784
Bronchiolar disease	Altered Intercellular Communication	IgG4-positive plasma cells may play a role in the pathogenesis of bronchiolar diseases associated with allergic airway inflammation.	20432975
Inflammation, Congenital vascular anomaly, Kidney Failure	Altered Intercellular Communication	T allele frequency was significantly higher in group of vascular and congenital cause of kidney failure (Pearson X2 =6.049, P<0.05) comparing to inflammation etiology group.	20433440
Multiple polyps, Disorder of olfactory system	Altered Intercellular Communication	Olfactory disorders linked to a non-blocked area around the nasal meatus (degree 1 or 2 polyposis), together with sinonasal CT scans showing beginnings of ethmoidal inflammation, should be interpreted as incipient sinonasal polyposis.	20434719
Airway structure, Asthma	Altered Intercellular Communication	Asthmatics in remission and asthma patients with a slow FEV(1) decline had a similar extent of airway inflammation and remodeling in sputum and bronchial biopsies.	20434897
Airway structure	Altered Intercellular Communication	Asthma, even when in remission, is accompanied by airway inflammation and remodeling.	20434897
Autoimmune enteropathy, Inflammatory abnormality of the eye	Altered Intercellular Communication	The ocular surface inflammation in GO seems to be due to both the dry eye and the autoimmune orbitopathy.	20435595
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Acute serum amyloid A induces migration, angiogenesis, and inflammation in synovial cells in vitro and in a human rheumatoid arthritis/SCID mouse chimera model.	20435930
Inflammation	Altered Intercellular Communication	Serum amyloid A (A-SAA), an acute-phase protein with cytokine-like properties, is expressed at sites of inflammation.	20435930
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Uncoupling of collagen II metabolism in newly diagnosed, untreated rheumatoid arthritis is linked to inflammation and antibodies against cyclic citrullinated peptides.	20436079
Uveitis	Altered Intercellular Communication	Incidence and characteristics of acute intraocular inflammation after intravitreal injection of bevacizumab: a retrospective cohort study.	20436545
Uveitis	Altered Intercellular Communication	To determine the incidence and characteristics of acute intraocular inflammation after intravitreal bevacizumab injections from a tertiary care retinal practice.	20436545
Vitritis, Inflammation	Altered Intercellular Communication	We reviewed the records of all patients with severe anterior chamber inflammation and (or) vitritis after bevacizumab injections.	20436545
Uveitis	Altered Intercellular Communication	There were a total of 9 cases of acute intraocular inflammation for an incidence of 1.30% (95% CI: 0.69%-2.47%).	20436545
Low Vision, Glaucoma, CTCAE	Altered Intercellular Communication	The mean loss of vision was 6.1 lines of Snellen visual acuity; one patient developed inflammation-induced glaucoma which required surgical intervention.	20436545
Uveitis, Unspecified visual loss	Altered Intercellular Communication	Intravitreal injection of bevacizumab is associated with a low but significant risk of acute intraocular inflammation and may result in significant visual loss.	20436545
Clostridium difficile, Diarrhea, Gastrointestinal inflammation	Altered Intercellular Communication	Diarrhea, clostridium difficile, and intestinal inflammation in residents of a long-term care facility.	20439046
Diarrhea, Gastrointestinal inflammation, Clostridium difficile colitis	Altered Intercellular Communication	Diarrhea and the presence of C difficile in the stool are associated with intestinal inflammation, as detected by fecal lactoferrin.	20439046
Colonization, Weight decreased, Gastrointestinal inflammation	Altered Intercellular Communication	With our small numbers, we were not able to identify a specific link; however, we were able to identify a correlation between weight loss and intestinal inflammation, but, with just 2 samples, not C difficile colonization.	20439046
Inflammation, Endothelial dysfunction, Obesity	Altered Intercellular Communication	Association of obesity and biomarkers of inflammation and endothelial dysfunction in adults in Inner Mongolia, China.	20439121
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Both inflammation and endothelial dysfunction are associated with increased risk of CVD.	20439121
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	We examined the association between body mass index (BMI) and waist circumference (WC) with plasma concentrations of biomarkers of inflammation and endothelial dysfunction.	20439121
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	WC is a stronger predictor of inflammation while BMI is a stronger predictor for endothelial dysfunction.	20439121
Inflammation, Hypoxia	Altered Intercellular Communication	This is the first study to show a direct in vivo correlation between synovial tPO(2), inflammation and cell migration, thus it is proposed that hypoxia is a possible primary driver of inflammatory processes in the arthritic joint.	20439288
Sublingual Region, Inflammation	Altered Intercellular Communication	In 32.9% of the patients at the time of first examination the extension of inflammation into parapharyngeal, pterygomandibular spaces or neck together with mouth floor cellulitis was diagnosed.	20440093
Inflammation	Altered Intercellular Communication	Histologic and microbiologic evaluation demonstrated florid inflammation and proof of Staphylococcus aureus was found intra-operatively.	20440468
Inflammation, Burn injury	Altered Intercellular Communication	The role of leukocyte adhesion molecules in patients with burns and their relationship to other parameters of inflammation and lipid metabolism is only recently beginning to be explored.	20441058
Inflammation, Cholelithiasis	Altered Intercellular Communication	A higher incidence of acute inflammation in the cholelithiasis (22.5% vs 9.5%, p = not significant [ns]) and in the H pylori positive groups (33% vs 17.6%, p = ns) were histologically detected.	20441060
Inflammation, Helicobacter pylori, Biliary calculi, Pathogenic organism	Altered Intercellular Communication	A higher incidence (10% vs 0%), p = ns) of H pylori in gallbladders with gallstones and acute inflammation, compared to gallbladders with acute inflammation but without gallstones, was noticed Helicobacter pylori is detectable in low frequency in the mucosa of the gallbladder and it does not seem to act as a lithogenic component for cholesterol gallstone formation.	20441060
Inflammation, Cholelithiasis, Biliary calculi	Altered Intercellular Communication	Its higher incidence in gallbladders with gallstones and acute inflammation, suggests a possible accessory role in a subset of patients with cholelithiasis.	20441060
Encephalitis, Sinusitis, Inflammation, Meningitis	Altered Intercellular Communication	Eleven cases were checked with magnetic resonance imaging (MRI) and four cases showed characteristics of encephalitis or meningitis, two with images of naso sinusitis and ethmoid-mastoid inflammation.	20441698
Pancreatitis, Jejunum	Altered Intercellular Communication	Computed tomography imaging showed a jejunal hematoma and pancreatitis with peripancreatic inflammation.	20442524
Inflammation, Normocytic anemia, Lupus Erythematosus	Altered Intercellular Communication	A laboratory picture of chronic inflammation, normocytic anaemia and a finding of lupus anticoagulant/antiphospholipid antibodies were observed.	20442651
Inflammation	Altered Intercellular Communication	Furthermore, the findings also indicate that T-cell apoptosis is perhaps a host regulatory mechanism to limit inflammation, rather than a pathogen-induced immune deviation.	20443851
Inflammation, Bone necrosis	Altered Intercellular Communication	Synovial inflammation in patients with osteonecrosis of the femoral head.	20443906
Inflammation	Altered Intercellular Communication	We hypothesized that patients with ON exhibit synovial inflammation.	20443906
Inflammation	Altered Intercellular Communication	Using immunohistological techniques, we found that a large population of patients with ON had synovial inflammation.	20443906
Inflammation, Corneal Endothelial Cell Loss	Altered Intercellular Communication	Markers of inflammation, fibrinolysis, endothelial damage, and oxidative stress were measured after each treatment.	20444914
Inflammation, Corneal Endothelial Cell Loss, diabetic	Altered Intercellular Communication	Ruboxistaurin did not significantly change endothelium-dependent or endothelium-independent vasodilation or blood-based markers of inflammation, fibrinolysis, endothelial damage, and oxidative stress in either diabetic or healthy subjects.	20444914
Neurotransmitters, Neurodegeneration Due To Cerebral Folate Transport Deficiency	Altered Intercellular Communication	A lumbar puncture done to look for neurotransmitter defects or cerebral folate deficiency revealed low levels of 5-methyltetrahydrofolate (31 nmol/L; reference range, 40-150 nmol/L).	20445197
perianal lesion	Altered Intercellular Communication	Inflammation of the ileon was found in 70.5% (47% ileocolonic and ileal 23.5%), nine (53%) had perianal lesions.	20445720
Inflammation, Ulcer	Altered Intercellular Communication	The macroscopic lesions were predominant stenosis 13 (76.5%), followed by ulcers in 12 (70.6%), erosive erythematous inflammation 11 (64.7%) and thickening of folds in 10 (58.8 %), seven (41%) had fistulas.	20445720
Inflammation, Biliary calculi, Congenital Abnormality	Altered Intercellular Communication	It consists of acute distension of the gallbladder without associated congenital anomalies, biliary calculi or acute local inflammation.	20446398
Inflammation, Observation Method - Coagulation, HIV Infections	Altered Intercellular Communication	Markers of inflammation, coagulation, and renal function are elevated in adults with HIV infection.	20446848
Inflammation, HIV	Altered Intercellular Communication	Human immunodeficiency virus (HIV) replication and immune activation may increase inflammation and coagulation biomarkers.	20446848
Papillary thyroid carcinoma, Inflammation, Autoimmune Diseases	Altered Intercellular Communication	The tight relationship between papillary thyroid cancer, autoimmunity and inflammation: clinical and molecular studies.	20447069
Inflammatory abnormality of the eye	Altered Intercellular Communication	This case highlights the significance of a history of PMR in patients with ocular inflammation.	20447103
Inflammation, Heart failure	Altered Intercellular Communication	The purpose of this study was to evaluate the association between inflammation and heart failure (HF) risk in older adults.	20447537
Inflammation, Atrial Fibrillation by ECG Finding, Corneal Endothelial Cell Loss	Altered Intercellular Communication	We have evaluated if the systemic biomarkers of inflammation and endothelial damage, vascular cell adhesion molecule-1 (VCAM-1) and soluble thrombomodulin may help in identifying patients prone to development of post-operative atrial fibrillation.	20447702
Inflammation	Altered Intercellular Communication	In disease-negative women, cervical inflammation was associated with an increase in VIA positivity from 6.1% to 15.5% (P<0.001).	20447927
Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation plays a key role in acute coronary syndromes (ACS).	20447947
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	Patients with inflammation were more likely to progress clinically in terms of lower urinary tract symptoms (LUTS), acute urinary retention (AUR), or BPH-related surgery.	20448364
Hyperparathyroidism, Chronic Kidney Diseases, Hypocalcemia	Altered Intercellular Communication	Elevated serum parathyroid hormone (PTH) level together with hypocalcemia in chronic kidney disease usually suggests secondary hyperparathyroidism.	20449656
Inflammation, Juvenile rheumatoid arthritis	Altered Intercellular Communication	Expression of FLICE-inhibitory protein in synovial tissue and its association with synovial inflammation in juvenile idiopathic arthritis.	20449949
Juvenile arthritis, Inflammation, Juvenile rheumatoid arthritis	Altered Intercellular Communication	To examine the expression of FLICE-inhibitory protein (FLIP) in juvenile idiopathic arthritis (JIA) and analyze its correlation with synovial inflammation.	20449949
Inflammation	Altered Intercellular Communication	The cell types expressing FLIP were further characterized, and the correlation of FLIP expression with the degree of synovial inflammation, as well as the activity of caspase 8 was then analyzed.	20449949
Juvenile arthritis, Inflammation	Altered Intercellular Communication	Moreover, the expression of FLIP in JIA synovial tissues was positively correlated with the degree of synovial inflammation (r = 0.563, P < 0.05).	20449949
Inflammation, Dental Plaque	Altered Intercellular Communication	Conversely, less width of KM is significantly associated with more gingival inflammation, more plaque accumulation, and more gingival recession.	20450368
Airway structure, Inflammation, ARCN1 gene	Altered Intercellular Communication	Chronic inflammation, especially airway inflammation, still exists in patients with stable COPD, as suggested by the different expressions of GCR and NF-kappaB between COPD patients and normal controls.	20450542
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Fever due to inflammation in acute aortic dissection: Description and proposals for diagnostic and therapeutic management.	20450855
Inflammation, Attachment (action)	Altered Intercellular Communication	Khat chewing may reduce aspects related to risk of gingival and periodontal inflammation, but it appears to be associated with attachment loss at the site of chewing.	20451834
Inflammation, Coronary Artery Disease, Ventricular Dysfunction	Altered Intercellular Communication	Neopterin, a marker of inflammation and macrophage activation, is a predictor of left ventricular dysfunction in patients with coronary artery disease.	20451908
Fibrous, Inflammation, Liver diseases	Altered Intercellular Communication	Typical aspects of normal liver architecture and liver diseases, such as nuclei, sinusoids, fibrous tissue, fatty inclusions, and bile ducts but not inflammation could be visualized at high resolution.	20452700
Inflammation, Hyperplasia, Edema	Altered Intercellular Communication	Of all analyzed lesions 88 were benign (inflammation, edema, hyperplasia etc.)	20452899
Inflammation, Candida (fungus), Barrett Esophagus, Gastroesophageal reflux disease, Deglutition Disorders, Failure (biologic function)	Altered Intercellular Communication	Reasons for diagnostic failure and delay included: delayed request for endoscopy in patients with dysphagia (49%, n=18 of 37); poor recognition of typical endoscopic appearances of EOE (16%, n=6 of 37); clinical mislabelling as gastro-oesophageal reflux disease (22%, n=8 of 37) and candida (13%, n=5 of 37); histological mislabelling as gastro-oesophageal reflux disease (19%, n=7 of 37), candida (5%, n=2 of 37), 'inflammation' (8%, n=3 of 37) and Barrett's oesophagus (3%, n=1 of 37); failed recognition or recording of maximal eosinophil concentrations within biopsies (35%, n=13 of 37).	20453656
Pneumonitis	Altered Intercellular Communication	Widespread lung inflammation and increased pulmonary vascular permeability has been noted on autopsy.	20453703
Gonorrhea	Altered Intercellular Communication	Combined hormonal contraception may be protective against Neisseria gonorrhoeae infection.	20453722
Gonorrhea, Neisseria gonorrhoeae	Altered Intercellular Communication	The role of hormonal contraception on acquisition of gonorrhea has not been well-characterized, as the transmission dynamics of Neisseria gonorrhoeae are poorly understood.	20453722
Inflammation, Edema, Cellulitis	Altered Intercellular Communication	Cellulitis, an acute, spreading pyogenic inflammation of the dermis and subcutaneous tissue, predisposed by persistent leg edema, can become problematic in patients on intraspinal opioid infusion therapy.	20456078
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Infiltrating monocytes and macrophages contribute to the initiation and perpetuation of mucosal inflammation characteristic for human inflammatory bowel disease (IBD).	20456413
Inflammation, Ischemic stroke	Altered Intercellular Communication	Inflammation and activated leucocytes are involved in the pathogenesis of acute ischaemic stroke.	20456424
Inflammation, Granulation finding	Altered Intercellular Communication	Histologically, a dermal small vessel proliferation with mixed inflammation (granulation tissue-like changes) was identified in 58% of specimens.	20456544
Inflammation	Altered Intercellular Communication	Haemodialysis patients show signs of chronic inflammation and reduced appetite, which is associated with a worse clinical status and an increased mortality risk.	20456591
Airway structure, Asthma	Altered Intercellular Communication	Exposure to particulate matter (PM) can induce airway inflammation and exacerbation of asthma.	20456673
Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is an inflammatory condition where cysteinyl leukotrienes have been identified to play an important role.	20456754
Inflammation, Fibrosis Assessment, Infection	Altered Intercellular Communication	Cystic fibrosis (CF) affects the lungs causing infections and inflammation.	20457545
Inflammation, Crohn Disease	Altered Intercellular Communication	Vulvar inflammation as the only clinical manifestation of Crohn disease in an 8-year-old girl.	20457677
Granulomatous inflammation	Altered Intercellular Communication	We report here the case of an 8-year-old girl with chronic vulvar edema, which on biopsy revealed granulomatous inflammation of the vulva.	20457677
Inflammation, Bacterial Infections	Altered Intercellular Communication	Results of the biological workup were negative for general inflammation, vitamin deficiency, and bacterial and viral infections.	20457964
Inflammation, Keratopathy	Altered Intercellular Communication	There was resolution of the inflammation; however, bullous keratopathy was subsequently noted in the cornea.	20458221
Inflammatory abnormality of the eye, Corneal Perforation	Altered Intercellular Communication	Rituximab may be the elective treatment for severe anterior ocular inflammation associated with risk for corneal perforation, as a result of WG.	20458228
Inflammation, Anemia, Hematemesis	Altered Intercellular Communication	A 73-year-old man was admitted to the hospital due to severe hematemesis and collapse, severe anemia and inflammation.	20458458
Inflammation, Thickened	Altered Intercellular Communication	The puncture of a peritoneal thickening also showed inflammation.	20458459
Pancreatitis, Acute, Inflammation, Pancreatitis	Altered Intercellular Communication	Cryoaffection on pancreatic gland stump during PDR performance have resulted in lowering of early postoperative complications frequency (pancreatic fistula, parapancreatic septic inflammation and an acute pancreatitis) and of chronic pancreatitis acute phase evolvement risk in the late postoperative period.	20458943
Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	As an early phase of interstitial inflammation preceded peritubular fibrosis in the rat model of AAN, the aim was to investigate the presence of inflammatory cells in human AAN.	20459552
Interstitial inflammation	Altered Intercellular Communication	Reports of confirmed cases and case series of AAN were reviewed in terms of interstitial inflammation and found to have very conflicting results.	20459552
Inflammation, Hepatic inflammation, Hypomagnesemia	Altered Intercellular Communication	Hypomagnesemia is defined by serum magnesium concentrationsor=40 U/L, and systemic inflammation by serum high-sensitivity C reactive protein (hs-CRP) concentration>or=3 mg/L.	20460213
Single organ dysfunction, Inflammation, Pancreatitis, Acute	Altered Intercellular Communication	Angiopoietin-2, a regulator of vascular permeability in inflammation, is associated with persistent organ failure in patients with acute pancreatitis from the United States and Germany.	20461065
Inflammation	Altered Intercellular Communication	A fistulectomy was performed and the pathological study showed a granulomatous-tuberculous chronic inflammation.	20461312
Inflammation	Altered Intercellular Communication	Recent data suggest a possible role for inflammation in this disease process.	20462916
Inflammation, Idiopathic Pulmonary Fibrosis, Traumatic injury	Altered Intercellular Communication	Idiopathic pulmonary fibrosis (IPF) is caused by alterations in expression of proteins involved in multiple pathways, including matrix deposition, inflammation, injury, and repair.	20463180
Inflammation, Malnutrition	Altered Intercellular Communication	Malnutrition, inflammation, and lipids in a cohort of dialysis patients.	20463430
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Previous studies implicated acetylcholinesterase (AChE) involvement in stroke, and circulating AChE activity reflects inflammatory response, since acetylcholine suppresses inflammation.	20464061
Inflammation, Pseudoaneurysm	Altered Intercellular Communication	In the absence of clinical signs of inflammation, this pseudoaneurysm was successfully treated by ultrasound-guided thrombin injection.	20464675
Gingivitis, Gingival Hemorrhage	Altered Intercellular Communication	A 13-year-old African American male presented with severe gingival inflammation, generalized gingival bleeding, and tooth looseness.	20465032
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	C-reactive protein (CRP), a representative marker for inflammation, is known for its association with disease progression in many cancer types.	20465852
Neutrophilia (finding)	Altered Intercellular Communication	The lesions were largely devoid of dermal, septal, or lobular neutrophilic or lymphocytic inflammation.	20466175
Inflammation	Altered Intercellular Communication	We hypothesize that the elevated apoB phenotype may be key therapeutic target to reduce obesity-associated inflammation and IR maximally by hypocaloric-dietary-interventions.	20466372
Inflammation, Atrial thrombosis, Non-rheumatic atrial fibrillation	Altered Intercellular Communication	Systemic inflammation and left atrial thrombus in patients with non-rheumatic atrial fibrillation.	20466519
Inflammation	Altered Intercellular Communication	There is an apparent link between thrombogenesis and inflammation.	20466519
Inflammation, Blood Clot, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	We hypothesized that systemic inflammation [as indicated by C-reactive protein (CRP)] would be related to the presence of left atrial (LA) thrombus in patients with atrial fibrillation (AF).	20466519
Inflammation	Altered Intercellular Communication	After TKA, control of local inflammation is much more important than control of systemic inflammation.	20466551
AVP gene	Altered Intercellular Communication	Recent cases of this disorder in which the pituitary gland was affected include cases of diffuse enlargement of the pituitary and/or its stalk associated with central diabetes insipidus and/or impaired anterior hormone production.	20467161
Inflammation, Thrombus, Dental Plaque	Altered Intercellular Communication	The serum markers of platelet activation (sP-selectin), inflammation (TNF-alpha and erythrocyte sedimentation rate), thrombotic state (fibrinogen) and plaque disruption were significantly higher in both UA and AMI patients compared to the healthy controls.	20467748
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Haemodialysis induces endothelial dysfunction by oxidation and inflammation.	20470276
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Haemodialysis caused a significant increase in oxidative stress, inflammation and endothelial dysfunction markers.	20470276
Inflammation	Altered Intercellular Communication	Elevated visfatin related to markers of inflammation might represent a novel link between inflammation and adipocytokines in dialyzed patients.	20470278
Inflammation, Malnutrition	Altered Intercellular Communication	High-calcium dialysate: a factor associated with inflammation, malnutrition and mortality in non-diabetic maintenance haemodialysis patients.	20470300
Inflammation, Malnutrition	Altered Intercellular Communication	Chronic inflammation, which is common in dialysis patients, often causes malnutrition and even protein-energy wasting.	20470300
Inflammation, Malnutrition	Altered Intercellular Communication	However, the association of high-calcium dialysate with malnutrition and/or inflammation in non-diabetic maintenance haemodialysis patients remains unclear.	20470300
Inflammation, Malnutrition	Altered Intercellular Communication	Patients with high-calcium dialysate (n = 82) had a higher incidence of malnutrition and inflammation (61.0% vs 44.1% and 43.9%, respectively) than those with standard- and low-calcium dialysate (n = 528 and 107).	20470300
Inflammation, Malnutrition	Altered Intercellular Communication	The analytical results indicate that high-calcium dialysate is associated with malnutrition and inflammation as well as 2 year mortality in non-diabetic maintenance haemodialysis patients and the findings suggest that this population, even those with optimal mineral balance, should avoid high-calcium dialysate.	20470300
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Bacterial colonisation in chronic obstructive pulmonary disease (COPD) contributes to airway inflammation and modulates exacerbations.	20470372
Inflammation	Altered Intercellular Communication	On histopathology transmural acute and chronic inflammation and multiple giant cells were patent in temporal artery wall.	20470480
Communicable Diseases, Inflammation	Altered Intercellular Communication	The remaining 171 patients (41%) presented with endovascular infection but no evidence of inflammation of the device pocket.	20470904
Necrotizing granulomatous inflammation, Necrosis	Altered Intercellular Communication	Debridement of the lesion was carried out and tissue sent for histopathological examination which revealed chronic granulomatous inflammation with caseating necrosis.	20470910
Inflammation	Altered Intercellular Communication	Genes in pathways affecting inflammation, cellular stress and apoptosis are important, and the extent of inflammation in the lung could be affected by polymorphisms modifying these responses.	20471133
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	In the present study we have investigated whether a combination of potential functional polymorphisms in genes related to inflammation may modulate risk of NSCLC.	20471133
Angiolymphoid hyperplasia	Altered Intercellular Communication	Angiofollicular lymphoid hyperplasia (Castleman's disease) is a rare inflammatory condition.	20471210
Inflammation, Data types - Address	Altered Intercellular Communication	Ample evidence has shown that inflammation and reactive oxygen species (ROS) increase in the AD patient's brain.	20471471
Inflammation	Altered Intercellular Communication	An in vivo xenograft model showed that host IL6R expression is also increased and regulated by tumor-associated inflammation.	20471626
Uveitis	Altered Intercellular Communication	A 64-year-old white man from Southern California presented with chronic intraocular inflammation in the right eye that had lasted 18 months.	20471688
Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic protein-energy wasting, termed malnutrition-inflammation complex syndrome, is frequent in patients with chronic kidney disease and is associated with anemia, morbidity, and mortality in patients on maintenance dialysis therapy.	20471737
Inflammation, Tumor necrosis, Malnutrition	Altered Intercellular Communication	Markers of inflammation and malnutrition, including serum C-reactive protein, interleukin 6, tumor necrosis factor alpha, serum leptin, prealbumin, body mass index, and abdominal circumference.	20471737
Inflammation, Malnutrition	Altered Intercellular Communication	A structural equation model with 2 latent variables (malnutrition and inflammation factor) showed good fit to the observed data.	20471737
Inflammation, Cachexia	Altered Intercellular Communication	Our results confirm that MIS reflects both energy-protein wasting and inflammation in kidney transplant recipients.	20471737
Inflammation, Ischemic stroke	Altered Intercellular Communication	We hypothesized that polymorphisms in 5 genes related to thrombolytic and inflammation pathways will independently influence occurrence, severity, and 3-month functional outcome in patients with ischemic stroke.	20472470
Refractory anemias, Inflammation	Altered Intercellular Communication	One possible mechanism to explain the association between reduced FCGR3B CN and RA is the reduced clearance of immune complex during inflammation.	20472591
Degenerative polyarthritis, Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain in hand osteoarthritis is associated with inflammation: the value of ultrasound.	20472595
Pain Distress Question, Synovial Hypertrophy, Inflammation, 4-hydroxy-2-oxovalerate aldolase activity, effusion	Altered Intercellular Communication	GS synovitis, effusion, synovial thickening and PDS are associated with pain in HOA, suggesting a role for inflammation.	20472595
vascular inflammations, Hyperplastic Polyp	Altered Intercellular Communication	The aim of the study was to establish MP as surrogate markers for platelet, leukocyte and endothelial activation in VAD patients predicting platelet activation and vascular inflammation.	20472650
vascular inflammations	Altered Intercellular Communication	VAD patients had significantly increased levels of platelet microparticles (PMP) (VAD 1705+/-1100 cpm vs. co: 527+/-238 cpm, P=0.002), leukocyte microparticles (LMP) (VAD 43+/-16 cpm vs. co: 18+/-8 cpm, P<0.001) and endothelial microparticles (EMP) (VAD 135+/-66 cpm vs. co: 46+/-23 cpm, P<0.001) indicating enhanced vascular inflammation and pro-coagulation.	20472650
Airway structure, mucus secretion	Altered Intercellular Communication	TRQI could improved the Chinese medical signs and symptoms in the patients with AECOPD, possibly because of the decreasing plasma levels of IL-8 and NE which could improve response to airway inflammation and mucus hypersecretion.	20473738
Gingivitis, Peri-implant mucositis	Altered Intercellular Communication	The most common complications associated with both treatments were gingival inflammation and peri-implant mucositis.	20476636
Communicable Diseases, Inflammation	Altered Intercellular Communication	The metabolism of the trace elements is altered in infection or inflammation.	20476645
Inflammation	Altered Intercellular Communication	The extent of BOP exhibited a significant positive correlation with IL-18 in the Spearman rank correlation analysis (P = 0.039), which indicated a correlation between periodontal inflammation and systemic IL-18 levels.	20476884
Inflammation, Chronic Obstructive Airway Disease, Malnutrition, Obesity	Altered Intercellular Communication	The obesity paradox was verified and may be partly explained by low BMI mediated by malnutrition and systemic inflammation due to PAD or chronic obstructive pulmonary disease.	20478682
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Therefore, a detailed understanding of factors and mechanisms associated with the processes leading from inflammation to cancer could improve the therapeutic strategies against this disease.	20478763
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	This could lead to better definition of the disease state, and to an increased understanding of the relationships between chronic inflammation and cancer.	20478763
Fibrosis Assessment, Nephritis, Kidney Diseases	Altered Intercellular Communication	In animal models, interstitial angiotensin II (ang II) and AT1 receptor (AT1R) are key mediators of renal inflammation and fibrosis in progressive chronic nephropathies.	20478903
Pneumonitis, Blood Coagulation Disorders	Altered Intercellular Communication	Supernatant of stored platelets causes lung inflammation and coagulopathy in a novel in vivo transfusion model.	20479286
Pneumonitis	Altered Intercellular Communication	In healthy rats, transfusion of aged PLTs caused mild lung inflammation.	20479286
Pneumonitis	Altered Intercellular Communication	We conclude that transfusion of aged PLTs induces lung inflammation in healthy rats.	20479286
Crohn Disease, Specimen Type - Fistula, Stenosis	Altered Intercellular Communication	Magnetic resonance enterography demonstrated active Crohn disease in 57.5% of patients, chronic changes of Crohn disease without active inflammation (eg, stricture, fistula, or abscess) in 12.5% of cases, and no evidence of Crohn disease in 30% of cases.	20479346
Cholecystitis	Altered Intercellular Communication	Subsequent reinterpretation and additional imaging including magnetic resonance imaging suggested that the uptake in the liver was likely due to adjacent gallbladder inflammation.	20479586
Ulcerative Colitis, Colitis	Altered Intercellular Communication	We believe that severe colonic inflammation from UC was closely associated with the onset of ARDS of the patient.	20480533
Respiratory Distress Syndrome, Adult, Colitis	Altered Intercellular Communication	Both colonic inflammations and ARDS symptoms of the patient were resistant to any medical treatment including corticosteroids and antibiotics.	20480533
Inflammation, Fasciitis	Altered Intercellular Communication	Magnetic resonance imaging (MRI) revealed strong inflammation along the entire fascia of the right femur and necrotizing fasciitis.	20480846
Retinal Detachment, Inflammation	Altered Intercellular Communication	Following treatment with radiotherapy and rituximab, the patient's intraocular inflammation and retinal detachment resolved.	20482392
Inflammatory abnormality of the eye	Altered Intercellular Communication	Considering its safety profile, further studies are needed to refine its mechanism of action, optimal indications, and dosing in ocular inflammation.	20482403
Autoimmune Diseases, Inflammation, Necrotizing vasculitis	Altered Intercellular Communication	Necrotizing vasculitis is a complex phenomenon because of an inflammation of small and larger vessels with polymorph infiltration within the vessel walls and leukocytoclasis, occurring in several autoimmune diseases.	20482568
Inflammation	Altered Intercellular Communication	It has been hypothesized that intermittent peripheral EBV reactivation may drive continuing central inflammation.	20482607
Inflammation, Knee joint	Altered Intercellular Communication	Sixty-two (74.7%) knee joints were found clinically involved, while at least one US finding indicative of joint inflammation was obtained in 70 (84.3%) knee joints.	20483039
Inflammation, Metabolic Syndrome X, Dyslipidemias, Diabetes Mellitus, Depression, CTCAE, Obesity, Hypertension, CTCAE, Chronic Kidney Diseases	Altered Intercellular Communication	We determined disparities in major conventional (hypertension, dyslipidemia, smoking and diabetes), other conventional (underweight, obesity, metabolic syndrome, chronic kidney disease, alcohol use, tension, depression and body height) and non-conventional (current and cumulative inflammation markers) cardiovascular risk factors between 424 consecutive public and 202 private healthcare patients in mixed regression models.	20483045
Necrotizing granulomatous inflammation, Neurologic Deficits	Altered Intercellular Communication	We hypothesize that meningeal granulomatous inflammation compressed the exiting anterior roots which resulted in motor dysfunction with preservation of peripheral sensory fibers.	20483179
Inflammation, Campylobacter infection, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The grades of neutrophil activity (p<0.001) and chronic inflammation (p<0.001) were lower for Campylobacter infection than for East Asian CagA H. pylori-related infection.	20483675
Communicable Diseases, Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	C. hyointestinalis is the most common cause of non-H. pylori-related Giemsa positive infection, and is associated with lower grades of neutrophil activity and chronic inflammation than East Asian CagA H. pylori-related infection.	20483675
Inflammation	Altered Intercellular Communication	The mechanism that may trigger human AT inflammation on a cellular level still remains largely unknown.	20484010
Inflammation	Altered Intercellular Communication	Open heart surgery results in an extensive acute systemic inflammation.	20484010
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Inflammation plays a central role in the development and progression of coronary heart disease (CHD).	20484148
Inflammation, Carcinogenesis	Altered Intercellular Communication	Serum interleukin-6 (IL-6), a proinflammatory cytokine, is considered an indicator of inflammation and may be an indicator of colorectal carcinogenesis given that inflammation can promote carcinogenesis.	20484173
Inflammation, Carcinogenesis	Altered Intercellular Communication	Flavonols, which can be found in fruits and vegetables, may inhibit colorectal carcinogenesis partly by inhibiting inflammation.	20484173
Sepsis, Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	In sepsis, coagulation and inflammation are activated to restore homeostasis, but it is not known whether sepsis also alters tissue regeneration processes such as skin collagen synthesis.	20484539
Inflammation, Neoplasms	Altered Intercellular Communication	Copy number variation was associated with differences in tumor cell type, but not with differences in tumor pigmentation or reactive inflammation.	20484589
Inflammation, Ischemic stroke	Altered Intercellular Communication	Early inflammation has been suggested as an important factor contributing to unfavorable prognosis after acute ischemic stroke.	20484906
Inflammation, Brain Injuries, Ischemic stroke, Cerebrovascular accident	Altered Intercellular Communication	Our data show important differences in the early time course of several potential markers for the complex network of inflammation and brain damage after ischemic stroke depending on stroke outcome.	20484906
Uterine Cervicitis, Swallowing painful	Altered Intercellular Communication	One month after the surgery, the patient came to the emergency department complaining about progressive anterior cervical inflammation, with odynophagia.	20485050
Inflammation, Neoplasms	Altered Intercellular Communication	They may mimic chronic inflammation and be misdiagnosed, delaying treatment and allowing the tumor to devastate the visual system.	20485052
Inflammation, Diverticulitis	Altered Intercellular Communication	Acute uncomplicated diverticulitis (AUD) may show histologic and serologic signs of inflammation.	20485187
Inflammation, Histologic	Altered Intercellular Communication	CRP was the most sensitive marker of mild-moderate histologic damage, as it was increased in 4/10 (40%) patients scoring 0 or 1 in neutrophilic infiltrate (absence of mild active inflammation) (P=0.005).	20485187
Psoriasis, Ulcerative Colitis, Tumor necrosis, Rheumatoid Arthritis, Crohn Disease	Altered Intercellular Communication	Tumour necrosis factor-alpha (TNFalpha) has an important role in the pathogenesis of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, ulcerative colitis and psoriasis.	20485705
Adenocarcinoma, Inflammation, HIV Coinfection, Empyema	Altered Intercellular Communication	Histologically confirmed causes of the effusion were; metastatic adenocarcinoma in two(25%) of the cases; chronic nonspecific inflammation in another two(25%) and tuberculous empyema thoracis in three(37.5%) one of whom had TB and HIV coinfection and one(12.5%) of chronic bacterial parapneumonic empyema.	20486093
Inflammation	Altered Intercellular Communication	Systemic markers of inflammation are associated with cardiac allograft vasculopathy and an increased intimal inflammatory component.	20486911
Granulomatous inflammation, Inflammation	Altered Intercellular Communication	The pathological examination revealed granulomatous inflammation, acute and chronic inflammation or both.	20487616
Data types - Address, neuropathology disease	Altered Intercellular Communication	In summary, our findings indicate that neurosteroids are altered in temporal cortex in patients with AD and related to neuropathological disease stage.	20488256
Data types - Address	Altered Intercellular Communication	Neurosteroids may be relevant to the neurobiology and therapeutics of AD.	20488256
Inflammation	Altered Intercellular Communication	The patient was treated with intranasal antrostomy in which the underlying dental cause of the inflammation was also removed.	20489466
Xanthogranulomatous inflammation, Eyelid Sebaceous Gland Carcinoma	Altered Intercellular Communication	Sebaceous cell carcinoma of the eyelid: a rapidly enlarging lesion with massive xanthogranulomatous inflammation.	20489549
Inflammation, Atherosclerosis	Altered Intercellular Communication	Levels of circulating anti-Hsp60 antibodies may constitute a marker of inflammation in atherosclerosis.	20490736
Inflammation, Lumbar radiculopathy	Altered Intercellular Communication	The duration of nerve root block showed a negative correlation with the concentrations of acetate in CSF of the patients in Group R. In patients with lumbar radiculopathy, there is a possibility of increased aerobic metabolic activity or decreased gluconeogenic activity in patients with shorter symptom duration, and increased aerobic metabolic activity in patients with severe inflammation around a nerve root.	20490871
Inflammation, Neurotoxicity Syndromes	Altered Intercellular Communication	Post-stroke inflammation may induce upregulation of the kynurenine (KYN) pathway for tryptophan (TRP) oxidation, resulting in neuroprotective (kynurenic acid, KA) and neurotoxic metabolites (3-hydroxyanthranillic acid, 3-HAA).	20490917
Coronary Artery Disease	Altered Intercellular Communication	Patients with acute or chronic inflammatory conditions, coronary artery disease or creatinine clearance below 50 mL/min were excluded.	20491014
ARCN1 gene, Inflammation	Altered Intercellular Communication	Preasumably, chronic inflammation in bronchial tree in course of COPD could be predisposing factor for p53 mutation and synthesis of pathological p53 protein.	20491334
Inflammation	Altered Intercellular Communication	Although the precise mechanism of this relationship remains unclear, the role of chronic low-grade inflammation, chronic oxidative and mechanical stress and an increase in VEGF is discussed.	20491689
Refractory anemias, Rheumatoid Arthritis, destruction joint, Have Autoimmune or Inflammatory Condition, Hyperplasia	Altered Intercellular Communication	Main features of rheumatoid arthritis (RA), hyperplasia of fibroblast-like synoviocytes (FLS) and joint destruction are caused by inflammatory cytokines produced in chronic autoimmune inflammation.	20491788
Malnutrition, Inflammation, Calcification of coronary artery, Renal Osteodystrophy	Altered Intercellular Communication	Malnutrition, inflammation, and renal osteodystrophy parameters with resultant coronary calcification (CC) are associated with increased cardiovascular mortality in adults.	20491972
Inflammation, Stasis, Intrahepatic Route of Drug Administration	Altered Intercellular Communication	Although the pathogenesis of IH is unknown, a role for lymphatic stasis secondary to chronic inflammation or surgery has been suggested.	20492077
Eosinophilic disorder, Inflammation	Altered Intercellular Communication	IL-17A is involved in inflammation and IL-17E is able to induce Th2 cytokine production and eosinophilia.	20492545
Heart failure, Myocarditis, Muscular Dystrophy, Duchenne	Altered Intercellular Communication	Myocardial inflammation in Duchenne Muscular Dystrophy as a precipitating factor for heart failure: a prospective study.	20492678
Heart failure, Myocarditis, Doctor of Dental Medicine	Altered Intercellular Communication	We evaluated the role of myocardial inflammation as a precipitating factor in the development of heart failure in DMD.	20492678
Heart failure, Myocarditis, Doctor of Dental Medicine	Altered Intercellular Communication	DMD patients with myocardial inflammation documented by CMR had a rigorous progression to heart failure.	20492678
Inflammation, Anemia	Altered Intercellular Communication	However, the strongest correlation was observed between 30 and 60 min measurements (r=0.926, p<0.001), irrespective of age, sex and presence of anaemia or of inflammation.	20493427
ARCN1 gene, Inflammation	Altered Intercellular Communication	Only some variables that would represent a higher chronic inflammation and a lower exercise tolerance showed a statistical tendence in the dead patients group in a exacerbation of COPD.	20494350
Inflammation, Obesity	Altered Intercellular Communication	Low grade inflammation is a key feature of central obesity, characterized by elevated plasma levels of C-reactive protein (CRP).	20494358
Inflammation, Cardio-Renal Syndrome, LUC7L3 gene, Chronic heart failure, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	The combination of chronic kidney disease (CKD), chronic heart failure (HF), and anaemia, the so-called cardio-renal-anaemia syndrome (CRA) is associated with dysregulation of erythropoietin levels and inflammation.	20495204
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Twelve cases of chronic granulomatous inflammation of musculoskeletal tissues were used for the study.	20495271
Inflammation	Altered Intercellular Communication	Some inflammation factors have been shown to accelerate type 2 diabetes macrovascular complication (T2DMC).	20495833
Inflammation, Retinitis Pigmentosa, polychondritis, Immune-mediated	Altered Intercellular Communication	Relapsing polychondritis (RP) is a rare immune-mediated disease which is associated with inflammation in cartilaginous tissue throughout the body.	20495939
Inflammation, Hemorrhage, Communicable Diseases, Pituitary Apoplexy, Pituitary Adenoma, Rathke Cleft Cysts	Altered Intercellular Communication	Although pituitary apoplexy due to hemorrhage, inflammation, or infection due to an underlying Rathke's cleft cyst is difficult to diagnose pre-operatively, Rathke's cleft cyst should be included in the differential diagnosis, and early surgical treatment is needed, as for pituitary apoplexy caused by pituitary adenoma.	20495985
Dystrophy, Inflammation, Myotoxicity	Altered Intercellular Communication	Myofiber necrosis without prominent inflammation is a nonspecific finding in patients with dystrophies and toxic or immune-mediated myopathies.	20496415
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Granulomatous orbital inflammation associated with intraorbital titanium-impregnated acetate fiber.	20497088
Granulomatous inflammation, Orbital Pseudotumor	Altered Intercellular Communication	Orbital biopsy revealed granulomatous inflammation consistent with idiopathic orbital inflammatory syndrome (IOIS), or orbital pseudotumor.	20497088
Inflammatory Bowel Diseases	Altered Intercellular Communication	It is important for dermatologists and dermatopathologists to be aware of the occurrence of IR-LPD in patients being treated for inflammatory conditions, including inflammatory bowel disease.	20497356
Inflammation, Observation Method - Coagulation, Community acquired pneumonia	Altered Intercellular Communication	Coagulation and inflammation biomarkers may help predict the severity of community-acquired pneumonia.	20497384
Inflammation, Observation Method - Coagulation, Community acquired pneumonia	Altered Intercellular Communication	There are limited data on the relationship between the severity of community-acquired pneumonia (CAP) and biomarkers of inflammation and coagulation.	20497384
Inflammation, Atherosclerosis	Altered Intercellular Communication	At the time of the index procedure 21/23 (91,3%) patients required dialysis, 15/22 patients (68,2%) showed signs and symptoms of atherosclerosis and 17/20 (76,5%) of inflammation.	20497754
Inflammation, Tuberculosis, Communicable Diseases, Hepatitis C, Hypoalbuminemia	Altered Intercellular Communication	We excluded patients who had infectious risk (hepatitis C or B positive, HIV positive, purified protein derivative (PPD) positive or having a history of tuberculosis, having a tunneled dialysis catheter) to find patients having both hypoalbuminemia and inflammation.	20497755
Giant Cell Arteritis, Vasculitis, GCA gene	Altered Intercellular Communication	To define the specificity and extent of duplex sonography (DS) findings suggestive of vessel wall inflammation in patients with giant cell arteritis (GCA).	20498213
Refractory anemias, Have Autoimmune or Inflammatory Condition, Diastolic dysfunction	Altered Intercellular Communication	RA duration and IL-6 are independently associated with diastolic dysfunction, suggesting the impact of chronic autoimmune inflammation on myocardial function in RA.	20498217
Adenocarcinoma, Inflammation	Altered Intercellular Communication	We reported that adenocarcinomas with a bubblelike appearance (BLA) appear similar to old inflammation (J Comput Assist Tomogr 2009;33:42-48).	20498546
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Calprotectin, a major cytosolic protein of neutrophils, is increased in inflammatory bowel disease (IBD) and may be considered a suitable marker of intestinal inflammation.	20499020
Inflammation	Altered Intercellular Communication	Presence, degree and length of wall inflammation were evaluated.	20499020
Inflammation	Altered Intercellular Communication	The MRI degree of wall inflammation was graded with a 0-3 scoring system (0=absent 1=light 2=moderate 3=severe) by considering findings observed on T1 post Gd and T2 fat-suppressed images, as well as the degree of wall thickness.	20499020
hepcidin, Anemia	Altered Intercellular Communication	Hepcidin is a key hormone governing mammalian iron homeostasis and may be directly or indirectly involved in the development of most iron deficiency/overload and inflammation-induced anemia.	20499129
Inflammation, Iron deficiency anemia, Anemia, Chronic disease, hepcidin	Altered Intercellular Communication	To characterize serum hepcidin, iron and inflammatory indicators associated with anemia of chronic disease (ACD), we studied ACD, ACD concomitant iron-deficiency anemia (ACD/IDA), pure IDA and acute inflammation (AcI) patients and analyzed the associations between hepcidin levels and inflammation parameters in various types of anemia.	20499129
hepcidin, Anemia	Altered Intercellular Communication	Hepcidin is a key hormone governing mammalian iron homeostasis and may be directly or indirectly involved in the development of most iron deficiency/overload and inflammation-induced anemia.	20499129
Inflammation, Carcinogenesis	Altered Intercellular Communication	Chronic inflammation is suspected to have a role in breast carcinogenesis.	20499154
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic low-grade inflammation may induce chronic kidney disease in patients with type 2 diabetes.	20499416
Inflammation	Altered Intercellular Communication	The patients suffering from the diseases not related to the chronic inflammation of the paranasal sinuses.	20500579
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Systemic inflammation in chronic obstructive pulmonary disease: a population-based study.	20500811
ARCN1 gene, Inflammation	Altered Intercellular Communication	Our results provide population-based evidence that COPD is independently associated with low-grade systemic inflammation, with a different inflammatory pattern than that observed in healthy subjects.	20500811
Inflammation, Critical Illness	Altered Intercellular Communication	Ghrelin is not correlated to markers of inflammation or hepatic function in critically ill patients.	20500817
Gastric Emptying, Inflammation	Altered Intercellular Communication	Mechanisms of gastric emptying disturbances in chronic and acute inflammation of the distal gastrointestinal tract.	20501434
Inflammation	Altered Intercellular Communication	It is unclear why patients with inflammation of the distal bowel complain of symptoms referable to the upper gastrointestinal tract, specifically to gastric emptying (GE) disturbances.	20501434
Fibrosis Assessment	Altered Intercellular Communication	The pathways include (a) alveolar collapse, (b) incorporation of fibroblastic material into alveolar walls, and (c) cigarette smoke-related inflammation and fibrosis.	20501710
Carcinoma of lung, Pneumonitis, Infection	Altered Intercellular Communication	Our results highlight the potential for lung cancer risk reduction through treatments targeted toward C. pneumoniae infections and chronic pulmonary inflammation.	20501758
Increased insulin level, Inflammation, Colorectal Carcinoma, Obesity	Altered Intercellular Communication	Serum adiponectin, leptin, C-peptide, and homocysteine are indicators for obesity, hyperinsulinemia, and chronic inflammation, which have all been associated with colorectal cancer.	20501764
Inflammation, Leukocytosis, Anemia, Anorexia, Thrombocytosis, Fatigue	Altered Intercellular Communication	Within one week, her fatigue and anorexia markedly improved, and her laboratory abnormalities, including anemia, thrombocytosis, leukocytosis, and elevated markers of inflammation, all resolved.	20501803
Inflammation	Altered Intercellular Communication	The degree of inflammation during the acute phase was higher in patients who had increased urinary excretion of a(1)-microglobulin 6 years later compared with those with no a(1)-microglobulin excretion.	20502044
Inflammation, Anemia	Altered Intercellular Communication	A significant vitamin D3 deficiency observed in the majority of patients undergoing long-term HD contributes to the development of chronic inflammation, anemia, and indirectly, to endothelial cell injury.	20502401
Inflammation, Thrombosis	Altered Intercellular Communication	During the past decade, the role of inflammation in the pathophysiology of arterial thrombosis has been elucidated.	20502419
Inflammation, Venous Thrombosis	Altered Intercellular Communication	However, little is known about the relationship between inflammation and venous thrombosis.	20502419
Inflammation, Blood Clot	Altered Intercellular Communication	Recently, inflammation has been accepted as a possible mechanism through which different risk factors trigger thrombus formation in veins.	20502419
Venous Thrombosis, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Patients with idiopathic venous thrombosis have increased levels of circulating markers of inflammation and blood markers of endothelial dysfunction.	20502419
Inflammation, Venous Thrombosis, Endothelial dysfunction	Altered Intercellular Communication	The interrelationship between inflammatory markers and markers of endothelial dysfunction favour the hypothesis that inflammation could be involved in the etiopathogenesis of idiopathic venous thrombosis.	20502419
Inflammation, Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	There are several functions of the SAA protein, described in the context of inflammation, that are compatible with the mechanism of tumour invasion and metastasis.	20502455
Suppurative inflammation	Altered Intercellular Communication	The CSF cytological and biochemical findings were both positive for purulent inflammation in 76 % of patients.	20503157
Inflammation, Bacterial Infections	Altered Intercellular Communication	To evaluate the penetration of ceftriaxone into the cerebrospinal fluid (CSF) in patients with invasive bacterial infection and to define correlation between the penetration and laboratory markers of inflammation.	20503158
Airway structure, Cystic Fibrosis	Altered Intercellular Communication	Effects of a short-term rehabilitation program on airway inflammation in children with cystic fibrosis.	20503278
Communicable Diseases, Fibrosis Assessment	Altered Intercellular Communication	Respiratory therapy in cystic fibrosis (CF) consists of airway clearance, infection control, and reduction of airway inflammation.	20503278
Inflammation, Carcinogenesis	Altered Intercellular Communication	Sustained chronic inflammation in the prostate promotes prostate carcinogenesis.	20503397
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Subclinical inflammation may be a mechanism linking air pollution with type 2 diabetes.	20504758
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Plasma protein growth arrest-specific 6 levels are associated with altered glucose tolerance, inflammation, and endothelial dysfunction.	20504897
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Plasma Gas6 is associated with altered glucose tolerance, inflammation, and endothelial dysfunction.	20504897
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	It also may represent a novel independent risk factor of type 2 diabetes and a potential surrogate marker of inflammation and endothelial dysfunction.	20504897
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	CT reports were reviewed, and the likelihood of appendicitis was assigned a score on a five-point scale: score 1, definitely absent; score 2, nonvisualized appendix with no secondary signs of inflammation; score 3, equivocal; score 4, probable; and score 5, definitely present.	20505066
Conjunctivitis	Altered Intercellular Communication	Recurrence was associated with severe conjunctival inflammation and severe trichiasis (>10 lashes) at baseline.	20505197
Keratitis	Altered Intercellular Communication	A cascade involving these biologically active factors may regulate scleral and corneal inflammation.	20505198
Inflammation, Hematoma	Altered Intercellular Communication	The epidural hematoma was probably caused by the spread of inflammation from the sphenoid sinus.	20505297
Inflammation, Discitis	Altered Intercellular Communication	In cases of spondylodiscitis, spine surgeons should be careful about inflammation of major vessels with friable vessel walls anterior to the vertebrae.	20505562
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Evidence from laboratory studies suggests that chronic inflammation plays an important role in prostate cancer aetiology.	20506261
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	ERp57 expression was detected in 16 out of 17 patient biopsies and correlated with inflammation grades or fibrosis stages, while in 5 normal biopsies ERp57 expression was not detectable in hepatocytes.	20506389
Suppurative inflammation, Community-Acquired Infections, Pneumonia	Altered Intercellular Communication	For some years, an increasing incidence of MRSA outside the hospital environment (Community-acquired or Community-Associated MRSA, CA-MRSA) has been observed all over the world, which, contrary to the hospital strains, produces the leukocytotoxic toxin PVL and causes purulent inflammations of the skin and necrotizing pneumonia.	20506711
Sarcoidosis, Inflammatory abnormality of the eye	Altered Intercellular Communication	Medical records of pediatric patients evaluated between 1987 and 2008 were reviewed to identify those with ocular inflammation in whom a diagnosis of sarcoidosis was considered.	20506967
Air Embolism, Inflammation	Altered Intercellular Communication	Although hemodynamic compromise has long been regarded as the main mechanism-particularly with deep watershed infarction-there is some contradictory evidence from clinical and pathological studies for a role of microembolism, thought to result from plaque inflammation.	20508190
Inflammation, Carotid Stenosis, Cerebrovascular accident	Altered Intercellular Communication	In 16 consecutive patients with recent transient ischemic attack/minor stroke and ipsilateral 50% to 99% carotid stenosis, we prospectively obtained (1) plaque inflammation mapping with (18)F fluorodeoxyglucose positron emission tomography; (2) brain MRI and perfusion MR; and (3) transcranial Doppler detection of microembolic signals (MES).	20508190
Inflammation	Altered Intercellular Communication	We found the expected significant relationship between (1) degree of stenosis and severity of distal hemodynamic impairment in the watershed areas; and (2) degree of in vivo plaque inflammation and rate of MES/hr.	20508190
Inflammation, Stenosis, Air Embolism, Watershed infarct, carotid disease	Altered Intercellular Communication	This pilot study supports the idea that in symptomatic carotid disease, deep watershed infarcts result either from hemodynamic impairment secondary to severe lumen stenosis or from microembolism secondary to plaque inflammation.	20508190
Pneumonitis, Blood Coagulation Disorders	Altered Intercellular Communication	Supernatant of aged erythrocytes causes lung inflammation and coagulopathy in a "two-hit" in vivo syngeneic transfusion model.	20508493
Pneumonitis, Blood Coagulation Disorders	Altered Intercellular Communication	In healthy rats, transfusion of aged erythrocytes caused mild pulmonary inflammation but no coagulopathy.	20508493
Pulmonary Complication	Altered Intercellular Communication	Washing of aged erythrocytes may decrease pulmonary complications in patients with an inflammatory condition who are exposed to a blood transfusion.	20508493
Inflammation	Altered Intercellular Communication	Histopathologic and immunohistochemical evaluations confirmed that they were both predominantly junctional nevi with conspicuous chronic inflammation.	20508514
Inflammation, AATF wt Allele, evaporation	Altered Intercellular Communication	These results suggest that inflammation plays a role not only in severe DED but also in moderate evaporative DED.	20508732
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Circulating progenitor cells in patients with atrial fibrillation and their relation with serum markers of inflammation and angiogenesis.	20508899
Inflammation	Altered Intercellular Communication	Increased levels of inflammation markers and elevated activity of liver enzymes were observed in laboratory tests.	20509567
Inflammation	Altered Intercellular Communication	The biological significance of this infiltration, very similar to chronic inflammation, is unknown, but it is suspected as being related to the pathogenesis and progression of the BPH.	20510119
Inflammation, Depressed mood, Carotid Atherosclerosis	Altered Intercellular Communication	Autonomic nervous system, inflammation and preclinical carotid atherosclerosis in depressed subjects with coronary risk factors.	20510416
Inflammation, Atherosclerosis, Coronary Artery Disease, Depressed mood, Pathologic Intimal Thickening	Altered Intercellular Communication	We investigated the relationship between intima-media thickening (IMT) as an expression of preclinical atherosclerosis and coronary risk factors, including the autonomic nervous system and inflammation markers, in depressed subjects free from coronary artery disease.	20510416
Inflammation, Coronary Artery Disease, Depression, CTCAE	Altered Intercellular Communication	This is mainly due to patho-physiological mechanisms which connect depression and coronary artery disease, such as inflammation and imbalance of the autonomic nervous system.	20510416
Inflammation, Pneumothorax, Toxic effect	Altered Intercellular Communication	Acute toxicity included pneumothorax (1.5%) and mucosal inflammation (10%).	20510543
Granulomatous inflammation, Pericarditis, CTCAE	Altered Intercellular Communication	The presence of granulomatous inflammation on the biopsy and an elevated pericardial adenosine deaminase activity level retrospectively supported the diagnosis of tuberculous pericarditis.	20510915
Cystic Lesion, Inflammation, Carcinoma	Altered Intercellular Communication	The main cystic lesion was diagnosed to be solid-papillary carcinoma, but the area of the pectoralis muscle was diagnosed to be a "foreign body" inflammation.	20512549
Inflammation, Mass in breast	Altered Intercellular Communication	It was thought that the compression related to MMG and core needle biopsy induced an injury in the bulky breast mass with leakage of contents into adjacent tissue, resulting in the foreign body inflammation.	20512549
Bronchi, Asthma, Aspirin-Induced, Pneumonitis, Anguilla island	Altered Intercellular Communication	Aspirin-intolerant asthma (AIA), which is caused by non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin, causes lung inflammation and reversal bronchi reduction, leading to difficulty in breathing.	20513247
CLU protein, human, Ischemia, Inflammation, Communicable Diseases	Altered Intercellular Communication	Patients with critical limb ischaemia (CLI) suffer chronic inflammation, repeated infection, require intervention, and can have a protracted hospital stay.	20513273
Inflammation	Altered Intercellular Communication	OA- and ONFH-affected bone exhibits a similar pro-inflammatory cytokine and collagen expression profile suggesting a relationship on the molecular level of inflammation and collagenous matrix composition between both diseases.	20514432
Inflammation, Mycobacterium Infections	Altered Intercellular Communication	Multiple mucosal biopsies from the left maxillary sinus revealed necrotizing granulomatous inflammation suspicious of mycobacterial infection.	20514598
Inflammation	Altered Intercellular Communication	Uric acid is a cardiovascular risk marker associated with oxidative stress and inflammation.	20515852
Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Recently, atrial fibrillation (AF) has been associated with inflammation and oxidative stress.	20515852
Inflammation, Viral Encephalitis	Altered Intercellular Communication	The mechanisms underlying inflammation and immune responses in viral encephalitis are not fully understood.	20516723
Inflammation, Ear Inflammation	Altered Intercellular Communication	Results of diagnostic studies are usually interpreted as middle ear pathology (tubootitis, exudative otitis, middle ear inflammation).	20517271
Inflammation	Altered Intercellular Communication	T-2 weighted magnetic resonance imaging (MRI) at 8 weeks showed increased signal intensity compatible with inflammation in several pelvic limb muscles.	20517298
Infection caused by Helicobacter pylori	Altered Intercellular Communication	Our findings strongly indicate a preventive effect of JA intake on CAG by inhibiting H. pylori infection and reducing active mucosal inflammation.	20517325
Coronary Artery Disease	Altered Intercellular Communication	Inflammation markers in patients with coronary artery disease--comparison of intracoronary and systemic levels.	20517668
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Raised levels of inflammation markers are associated with worse prognosis in patients with coronary artery disease.	20517668
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	We observed that excess circulating inflammation markers, being characteristic of unstable coronary artery disease, are released from noncoronary sources.	20517668
Inflammation, Coronary heart disease	Altered Intercellular Communication	Thus, it may be speculated that systemic inflammation precedes local inflammation at the plaques, thereby transforming coronary disease from a stable to an unstable form.	20517668
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	In conclusion, although synovial inflammation remained active, the MMP-1, COX-2 and IL-1b expression in synovium decreased depending upon the severity of OA, while the TGF-b expression increased.	20517696
Hemorrhagic pleural effusion, Inflammation	Altered Intercellular Communication	Thoracentesis revealed hemorrhagic pleural effusion which was exudate and lymphocyte predominant, closed pleural biopsy showed chronic inflammation.	20517734
Erectile dysfunction	Altered Intercellular Communication	Drugs play a role in the pathogenesis of erectile dysfunction, as they can alter hormonal or vascular mechanics needed for achieving or maintaining erection.	20518197
Atherogenesis, Inflammation, Electrocardiogram: myocardial infarction (finding), Dental Plaque	Altered Intercellular Communication	uPA (urokinase-plasminogen activator) and its receptor (uPAR) have been implicated in a broad spectrum of pathophysiological processes, including fibrinolysis, proteolysis, inflammation, atherogenesis and plaque destabilization, all of which are involved in the pathogenesis of MI (myocardial infarction).	20518747
Gastroesophageal reflux disease, Inflammation	Altered Intercellular Communication	Transient receptor potential vanilloid-1 (TRPV1) receptor has been implicated in the mechanism of acid induced inflammation in gastro-esophageal reflux disease (GERD).	20518854
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Coronary heart disease	Altered Intercellular Communication	Lung function and risk of type 2 diabetes and fatal and nonfatal major coronary heart disease events: possible associations with inflammation.	20519659
Inflammation, Diabetes Mellitus, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	We prospectively examined the relationship between lung function and risk of type-2 diabetes and fatal and nonfatal coronary heart disease (CHD) events and investigated the hypothesis that inflammation may underlie these associations.	20519659
Inflammation, Lung Obstructive Function Score 1, Diabetes Mellitus, Non-Insulin-Dependent, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Restrictive rather than obstructive impairment of lung function is associated with incident type 2 diabetes (and fatal CHD) with both associations partially explained by traditional and metabolic risk factors and inflammation.	20519659
Inflammation, Autonomic nervous system disorders	Altered Intercellular Communication	Short-term elevation of ambient particulate air pollution has been associated with autonomic dysfunction and increased systemic inflammation, but the interconnections between these pathways are not well understood.	20519749
Inflammation	Altered Intercellular Communication	Increased systemic inflammation was defined for subjects within the upper 20% of the distribution for each marker.	20519749
Inflammation, Autonomic nervous system disorders	Altered Intercellular Communication	Increased systemic inflammation is associated with autonomic dysfunction in the elderly.	20519749
Inflammation, Disease	Altered Intercellular Communication	Human leukocyte antigen analysis showed B35 and B52, the typical haplotype in cases with coexistence of both diseases and associated sustained inflammation.	20519817
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis is an inflammatory bowel disease involving superficial inflammation of the mucosa of the colon, rectum, and anus, sometimes including the terminal ileum.	20520975
Inflammation, Progranulins, Neoplasms, GRN wt Allele	Altered Intercellular Communication	Progranulin (PGRN) is involved in wound repair, inflammation, and tumor formation, but its function in the central nervous system is unknown.	20522652
Sepsis, Inflammation	Altered Intercellular Communication	During sepsis, activation of phagocytes leads to the overproduction of proinflammatory cytokines, causing systemic inflammation.	20522778
Airway structure, Allergic asthma, Bronchial Hyperreactivity	Altered Intercellular Communication	Changes in airway inflammation and hyperresponsiveness after inhaled corticosteroid cessation in allergic asthma.	20523062
Airway structure, Asthma, Bronchial Hyperreactivity	Altered Intercellular Communication	The present study evaluates changes in airway inflammation and hyperresponsiveness in adult patients with asthma after stopping ICS.	20523062
Skin necrosis, Intraocular inflammation, Oculomotor Nerve Paralysis	Altered Intercellular Communication	After 3 months, visual acuity, all intraocular inflammation, oculomotor nerve palsy, and skin necrosis resolved completely except for a dilated pupil.	20523258
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To compare magnetic resonance imaging (MRI) and ultrasonography (US) in the detection of joint inflammation of rheumatoid arthritis (RA), 6 patients with RA were examined by US and low-field 0.3-T nonenhanced dedicated extremity MRI (compacTscan).	20524026
Joints, Structure of intercarpal joint, Inferior radioulnar joint structure, PIP gene, Arthritis	Altered Intercellular Communication	Intercarpal joints, radioulnar joints, second through fifth proximal interphalangeal (PIP) joints, and first through fifth metacarpophalangeal (MCP) joints (a total of 132 joints, 22 joints in each patient) were assessed by MRI for presence of joint inflammation.	20524026
Arthritis, Wrist joint	Altered Intercellular Communication	A total of 156 joints (24 first interphalangeal and radiocarpal joints plus the above 132 joints), were assessed by grayscale US (GS-US) and power Doppler US (PD-US) for presence of joint inflammation by two trained ultrasonographers.	20524026
Inflammation	Altered Intercellular Communication	ICC was 0.545 for GS-US and 0.807 for PD-US, suggesting specificity of PD-US in detecting joint inflammation.	20524026
Arthritis	Altered Intercellular Communication	We assessed correlations between joint inflammations on MRI and GS-US/PD-US, and also interobserver correlation between the two ultrasonographers by calculating intraclass correlation coefficients (ICC).	20524026
Refractory anemias, Inflammation, Rheumatoid Arthritis, Inflammatory disorder	Altered Intercellular Communication	Neutrophils and monocytes play an important role in overt inflammation in chronic inflammatory joint diseases such as rheumatoid arthritis (RA).	20525314
Inflammation	Altered Intercellular Communication	Identification of the molecular checkpoints critical for completion of the lymphoid neogenesis program should help develop innovative therapeutic strategies to fight chronic inflammation.	20525884
Inflammatory, Inflammation, Abnormal color	Altered Intercellular Communication	Oral postinflammatory pigmentation (OPP) is a discoloration of the oral mucosa caused by an excess of melanin production and deposition within the basal layer of the epithelium and connective tissue of areas affected by chronic inflammation.	20526252
Endothelial dysfunction, Diabetes Mellitus	Altered Intercellular Communication	Type-2 diabetes is accompanied by a prothrombotic state influenced by endothelial dysfunction, inflammatory condition and platelet hyperreagibility.	20526607
Respiratory complication, Inflammation, Actual blood loss, Edema	Altered Intercellular Communication	Third, minimally invasive esophagectomy might reduce respiratory complications and blood loss because this procedure reduces edema and inflammation in the lung.	20526722
Inflammation, Osteolysis	Altered Intercellular Communication	Biodegradable implants lead to problems such as cyst formation, soft-tissue inflammation, loose implant fragments or local osteolysis.	20526849
Inflammation, Primary peritoneal carcinoma, Actinomycosis	Altered Intercellular Communication	Pelvic CT and MRI were limited in their ability to differentiate inflammation, such as actinomycosis, from primary carcinoma of the peritoneum.	20527245
anti-endothelial cell antibody, Electrocardiogram: myocardial infarction (finding), Inflammation, Atherosclerosis	Altered Intercellular Communication	We report for the first time evidence that AECA are related to signs of inflammation and are increased in patients with atherosclerosis and previous myocardial infarction and with further increase with severity of disease.	20528242
Asthma, Bronchitis	Altered Intercellular Communication	Smoking has been shown to increase the lung function decline in adult asthma patients and change the composition of the bronchial inflammation.	20528587
vascular inflammations, Periodontitis, Atherosclerosis	Altered Intercellular Communication	Periodontitis is suggested to enhance the process of vascular inflammation leading to atherosclerosis.	20528962
Inflammation, Aortic Stiffness	Altered Intercellular Communication	Inflammation and the level of repetitive cyclic stress are important predictors of aortic stiffness, whereas wave reflection is predicted by acute inflammation only.	20530296
Inflammation, Infection, Impaired	Altered Intercellular Communication	Factors other than asbestos that may play a role include genetic predisposition, immune impairment, infections, radiation, dietary factors, and recurrent serosal inflammation.	20530447
Inflammation, Neoplasms	Altered Intercellular Communication	We consider that, in the presented case, inflammation and healing resulting from pericardiotomy might have had a synergistic effect with asbestos in the pathogenesis of the tumor.	20530447
Inflammation, Helicobacter pylori, Stomach Carcinoma, Gastritis, Intestinal metaplasia, Atrophic	Altered Intercellular Communication	Matched tumor/nontumor adjacent mucosa (NTAM) of 91 early gastric cancer and 148 chronic gastritis cases were evaluated for histologic characteristics (atrophy, intestinal metaplasia, chronic inflammation, polymorphonuclear infiltration, and Helicobacter pylori) by the Sydney System.	20530692
Atrophic	Altered Intercellular Communication	Histologically, NTAM have severe intestinal metaplasia/chronic inflammation and severe atrophy assessed by Sydney and OLGA staging systems.	20530692
Inflammation, Erosion lesion, Ulcer	Altered Intercellular Communication	Colonoscopy revealed ileal erosion, a longitudinal ulcer in the ascending colon but only mild rectal inflammation.	20530926
Cancer-related fatigue, Inflammation	Altered Intercellular Communication	These findings support the key role of CRF and fatness on low-grade inflammation, as well as the possible indirect role of habitual PA through CRF and body fat in adolescents.	20531354
Inflammation, Respiratory physiology	Altered Intercellular Communication	Inflammation is increasingly linked to loss of lung function and evidence suggests that consumption of dietary fat exacerbates inflammation.	20531437
Inflammation, Endophthalmitis, CTCAE, Ulceration, CTCAE, Perforation (observation)	Altered Intercellular Communication	Despite intensive treatment with topical and oral antifungal agents, scleral inflammation and ulceration progressed, and scleral perforation and endophthalmitis developed.	20532146
Inflammation	Altered Intercellular Communication	However, scleral and intraocular inflammation progressed, and the eye was enucleated.	20532146
Inflammation, Fatty degeneration	Altered Intercellular Communication	Mild to severe steatosis was noted in 7 patients (19%) and aspecific portal inflammation in 11 patients (30%).	20532569
Neurodegenerative Disorders, Neurogenic Inflammation, Inflammation, Parkinson Disease, palladium	Altered Intercellular Communication	Although neuroinflammation is known to play an important role in the pathogeneses of neurodegenerative diseases, few studies have been conducted on the association between Parkinson's disease (PD) and high-sensitivity C-reactive protein (hs-CRP), which is the most studied biomarker of systemic inflammation.	20532580
Pain Distress Question, Inflammation, Hypereosinophilia	Altered Intercellular Communication	One month later, he reported improvements in general health, pain, motion, joint mobility, and skin induration associated with normalization of both hypereosinophilia and biologic inflammation.	20532934
Intraocular inflammation, Eye Neoplasms, Disease, Uveitis	Altered Intercellular Communication	This inflammatory condition belongs to the uveitis masquerade syndromes, which comprise a group of various ocular diseases such as chronic intraocular inflammation and ocular tumors.	20533043
Intraocular inflammation, Eye Neoplasms, Disease, Uveitis	Altered Intercellular Communication	This inflammatory condition belongs to the uveitis masquerade syndromes, which comprise a group of various ocular diseases such as chronic intraocular inflammation and ocular tumors.	20533043
Pain Distress Question, Inflammation	Altered Intercellular Communication	A 50 g force could effectively induce tooth movement similar to 150 g with less pain and less inflammation.	20534713
Sepsis, Inflammation, Bacterial Infections	Altered Intercellular Communication	Procalcitonin, a well-known biomarker of sepsis and bacterial infections, is produced by adipose tissue and has potential as a marker for chronic low-grade inflammation.	20534760
Corneal edema	Altered Intercellular Communication	Eighteen eyes had corneal edema and 36 eyes had anterior chamber inflammation.	20534920
Alzheimers Disease	Altered Intercellular Communication	Alzheimer disease also involves glutamatergic neurotransmitter system disturbances.	20535038
Airway structure, Asthma	Altered Intercellular Communication	Measuring fractional exhaled nitric oxide (FeNO) provides an indication of airway inflammation and is used as an inflammatory marker for asthma management.	20536283
Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a systemic autoimmune disease that is characterized by chronic synovial inflammation.	20536605
Tissue damage	Altered Intercellular Communication	In contrast, tissue damage during the third postnatal week failed to significantly alter spontaneous excitatory or inhibitory synaptic transmission in the SDH.	20536930
Inflammation	Altered Intercellular Communication	The increase in CRP levels before onset of AF may support the hypothesis that systemic inflammation is an important trigger for AF.	20537138
Diabetic Nephropathy, Inflammation	Altered Intercellular Communication	Low-energy diet applied in diabetic nephropathy may decrease serum resistin levels and inflammation.	20537918
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation plays an important role in cardiovascular disease (CVD).	20538029
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	Lipoprotein(a), inflammation, and peripheral arterial disease in a community-based sample of older men and women (the InCHIANTI study).	20538138
Inflammation, Dental Plaque, Ischemic stroke	Altered Intercellular Communication	Systemic and intraplaque mediators of inflammation are increased in patients symptomatic for ischemic stroke.	20538699
Ischemic stroke	Altered Intercellular Communication	Thus, we investigated the possible role of systemic and intraplaque inflammation in patients asymptomatic versus symptomatic for ischemic stroke.	20538699
Inflammation, Cardiovascular Diseases, Hyperuricemia, Kidney Diseases, Hypertension, CTCAE	Altered Intercellular Communication	Hyperuricemia is associated with hypertension, inflammation, renal disease progression, and cardiovascular disease.	20538833
palladium, Inflammation, Overhydrated	Altered Intercellular Communication	Peritoneal dialysis (PD) patients may be overhydrated especially when inflammation is present.	20538836
Inflammation, Osage language, craniofacial development, Obesity, Sleep Apnea, Obstructive	Altered Intercellular Communication	Obstructive sleep apnea (OSA) is hypothesized to be influenced by genes within pathways involved with obesity, craniofacial development, inflammation, and ventilatory control.	20538960
Uveal melanoma, Inflammation, Humor	Altered Intercellular Communication	This study was conducted to determine whether the aqueous humor (AqH) from eyes with uveal melanoma contains inflammatory cytokines and whether their presence is associated with inflammation.	20538984
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Aberrations in apolipoprotein (apo) metabolism and increased systemic inflammation associate with the metabolic syndrome (MetS) and may contribute to its atherogenicity.	20539018
Inflammation	Altered Intercellular Communication	In conclusion, H. pylori-induced miR-146a plays a potential role in a negative feedback loop to modulate the inflammation by targeting IRAK1 and TRAF6.	20542134
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	These findings underscore the close interaction between inflammation and coagulation and provide evidence that these simple laboratory tests should be routinely considered during the early evaluation of the infected patient.	20542399
Inflammation, Dental Plaque, atherosclerotic	Altered Intercellular Communication	Eicosapentaenoic acid (EPA) from highly concentrated n-3 fatty acid ethyl esters is incorporated into advanced atherosclerotic plaques and higher plaque EPA is associated with decreased plaque inflammation and increased stability.	20542512
Inflammation, atherosclerotic	Altered Intercellular Communication	To examine n-3 polyunsaturated fatty acid (PUFA) incorporation into atherosclerotic plaques and the association with plaque inflammation and stability.	20542512
Inflammation, Dental Plaque	Altered Intercellular Communication	A higher plaque EPA content is associated with a reduced number of foam cells and T cells, less inflammation and increased stability.	20542512
Airway structure, Influenza virus	Altered Intercellular Communication	l-carbocisteine may reduce airway inflammation in influenza virus infection.	20543005
Dental Plaque	Altered Intercellular Communication	Identification of carotid plaque inflammation with PET can be performed 1 h after FDG injection using SUVmax for plaque FDG uptake quantification.	20543757
Communicable Diseases, Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Since lipoprotein-associated phospholipase A2 (Lp-PLA(2)) mediates inflammation in atherosclerosis, we hypothesized that serum Lp-PLA(2) mass and activity levels and plaque Lp-PLA(2) may be influenced by plaque C. pneumoniae infection.	20543948
Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	The significant association of plaque Lp-PLA(2) with plaque macrophages and C. pneumoniae suggests an interactive role in accelerating inflammation in atherosclerosis.	20543948
Pyelonephritis	Altered Intercellular Communication	Xanthogranulomatous pyelonephritis (XGP) is a chronic inflammatory condition of the kidneys.	20544282
Inflammation, Fever, CTCAE, Urticaria, Arthralgia, Gammopathy, Bone pain	Altered Intercellular Communication	Schnitzler syndrome is a rare disorder characterized by monoclonal IgM gammopathy, urticaria, recurrent fever, evidence of inflammation, bone pain, and arthralgia.	20544653
Inflammation, Osteopenia	Altered Intercellular Communication	A moderate correlation between TWEAK/Fn14 expression and inflammation and bone loss, but not pocket depth, was noted.	20546112
Inflammation, Periodontitis	Altered Intercellular Communication	Our data support the concept that TWEAK/Fn14 signaling is an additional player in the pathogenesis of periodontitis and adds to the increasing number of cytokine networks involved in periodontal inflammation.	20546112
Inflammation, Respiratory Aspiration of Gastric Contents	Altered Intercellular Communication	We also wished to determine whether an acidic environment in the lung influences pulmonary function and DL(CO), and whether microaspiration of gastric contents directly influences non-specific inflammation in the lung.	20546193
Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment	Altered Intercellular Communication	Age, serum total cholesterol, and hepatic necro-inflammation have important associations with severity of hepatic fibrosis in CHC patients.	20546452
Inflammation, Arteriopathic disease	Altered Intercellular Communication	Systemic inflammation may be a common factor behind such symptoms and the subsequent development of arterial disease.	20549275
ARCN1 gene, Airway structure	Altered Intercellular Communication	The percentage of neutrophils in sputum are increased in COPD patients, and may therefore be a biomarker of airway inflammation.	20550701
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	We studied the relationships between sputum neutrophils and FEV1, health status, exacerbation rates, systemic inflammation and emphysema, and long term variability at 1 year.	20550701
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Sputum neutrophil measurements were dissociated from exacerbation rates, emphysema and systemic inflammation.	20550701
Vertigo, hearing impairment, Inflammatory abnormality of the eye, Have Dizziness, Nausea	Altered Intercellular Communication	The administration of a combined immunosuppressive treatment resolved ocular inflammation, dizziness, nausea, and vertigo but gave little results in controlling progressive hearing loss.	20550723
Inflammation, Neoplasms	Altered Intercellular Communication	Current models of oncogenesis incorporate the contributions of chronic inflammation and aging to the patterns of tumor formation.	20551058
Inflammation, Scleroderma , Systemic Scleroderma	Altered Intercellular Communication	Characteristics of joint involvement and relationships with systemic inflammation in systemic sclerosis: results from the EULAR Scleroderma Trial and Research Group (EUSTAR) database.	20551097
Inflammation, Contracture of joint, Synovitis	Altered Intercellular Communication	Our data also show that synovitis, joint contracture, and tendon friction rubs are associated with a more severe disease and with systemic inflammation.	20551097
millicurie, Data types - Address	Altered Intercellular Communication	As most of these amino acids and metabolic compounds are functionally important for brain-specific metabolic processes, neurotransmitter pathways or compensatory mechanisms, our findings might reflect these changes occurring within the brain of patients with MCI and those who developed manifest AD.	20551690
Crohn Disease, Inflammation	Altered Intercellular Communication	Outcomes included acute pouchitis (antibiotic responsive), chronic pouchitis (antibiotic dependent or refractory), or de novo Crohn's disease (small inflammation above the pouch inlet or pouch fistula).	20551749
Inflammation, Necrosis	Altered Intercellular Communication	Cystic duct clips or hemostatic clips migrating into the common bile duct after biliary surgery, although rare are well recognized and assumed to relate to improper clip application, bile leak (usually subclinical), inflammation, and subsequent necrosis, allowing the clips to erode directly into the common bile duct.	20551787
Inflammation, Weight decreased	Altered Intercellular Communication	The mean concentrations of inflammation parameters decreased during a period of weight loss and dietary intervention.	20551965
Orbital Pseudotumor	Altered Intercellular Communication	Digital infrared thermal imaging (DITI) detects local temperature and may reflect the degree of orbital inflammation.	20553230
Inflammation	Altered Intercellular Communication	Basal temperature of the eyes measured by DITI was an objective indicator of inflammation of GO.	20553230
Obesity	Altered Intercellular Communication	Obesity is associated with increased hs-CRP levels in 6-12 year-old children, a finding that supports the inflammation-obesity hypothesis at an early stage of life.	20554094
Inflammation, Atherosclerosis	Altered Intercellular Communication	Occult impaired glucose regulation in patients with atherosclerosis is associated to the number of affected vascular districts and inflammation.	20554281
square decimeter, Cardiovascular Diseases	Altered Intercellular Communication	The role of inflammatory adipokines has clear mechanistic effects in the promotion of both DM2 and cardiovascular diseases (CVDs), but it is unknown to what extent atherosclerosis-related inflammation might promote defects of glucose metabolism.	20554281
Pain Distress Question, Inflammation, Gastrointestinal Pain, CTCAE, Fever, CTCAE, Bothered by Vomiting, Diarrhea, Nasopharyngitis, Edema, Joint swelling, Fatigue	Altered Intercellular Communication	These were clustered into five groups: fever; musculoskeletal (pain and joint swelling); gastrointestinal (abdominal pain, vomiting, diarrhea); eye inflammation; and general (including fatigue, nasopharyngitis, edema).	20554708
Inflammation, Primary malignant neoplasm, Communicable Diseases, Hyperglycemia, Diabetes Mellitus	Altered Intercellular Communication	Do hyperglycemia and diabetes affect the incidence of false-negative 18F-FDG PET/CT studies in patients evaluated for infection or inflammation and cancer?	20554733
Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	(18)F-FDG PET/CT studies of 123 consecutive patients investigated for suspected infection or inflammation and 320 patients evaluated for malignancy were retrospectively analyzed.	20554733
Communicable Diseases, Inflammation	Altered Intercellular Communication	In the infection or inflammation group, 19 of 123 patients (15%) had serum glucose levels greater than 180 mg/dL and 43 of 123 (35%) had DM.	20554733
Communicable Diseases, Inflammation	Altered Intercellular Communication	Neither glucose levels nor DM affects the detection rate of infection or inflammation with (18)F-FDG PET/CT.	20554733
Inflammation	Altered Intercellular Communication	SUVmax assessment may allow an objective, reliable indication of the grade and severity of inflammation activity in abnormal segments of the bowel detected by CT enterography.	20554741
Inflammation	Altered Intercellular Communication	Downregulated genes reflected several biological pathways such as inflammation, angiogenesis, B- and T-cell activation.	20555356
Proteinuria, Inflammation, Hematuria, CTCAE, Anemia	Altered Intercellular Communication	On admission, his blood pressure was 166/92 mmHg, and laboratory findings showed signs of inflammation, anemia, proteinuria, and hematuria.	20556459
Inflammation, bone destruction, Neoplasms, Infection, Fracture	Altered Intercellular Communication	Active pathological bone destruction in humans often occurs in locations where oxygen tension (pO(2)) is likely to be low, for example, at the sites of tumours, inflammation, infections and fractures, or the poorly vascularized yellow fatty marrow of the elderly.	20556743
Inflammation, Saint Lucia	Altered Intercellular Communication	Inflammation was diagnosed in 70.7% of open cholecystectomy (OC) and 42.1% of LC patients.	20557412
Autoimmune Diseases, Primary Biliary Cholangitis, Hepatitis	Altered Intercellular Communication	Primary biliary cirrhosis (PBC) is an organ-specific autoimmune disease of still unidentified genetic etiology that is characterized by chronic inflammation of the liver.	20557968
Macroprolactinemia, Hyperprolactinemia	Altered Intercellular Communication	His hormonal evaluation indicated a marked hyperprolactinemia mainly due to macroprolactinemia (total prolactin, 514 ng/ml; reference range, 1.6-10.7 ng/ml; macroprolactin 436 ng/ml, monomer prolactin 78.2 ng/ml).	20558354
Heart Ventricle, Sleep Apnea, Obstructive, Inflammation, Osage language	Altered Intercellular Communication	N-terminal pro-B-type natriuretic peptide (NT-proBNP), a marker of ventricular strain, and C-reactive protein (CRP), a marker of inflammation, are reportedly elevated in school-aged children with obstructive sleep apnea (OSA).	20558551
Inflammation, Hypoxemia, Osage language	Altered Intercellular Communication	Echocardiographic parameters suggesting increased pulmonary pressure in young children with OSA are related to nocturnal hypoxemia and systemic inflammation, which also decrease following therapy.	20558551
Inflammation	Altered Intercellular Communication	Magnetic resonance imaging of this patient's brain suggested inflammation of the bilateral basal ganglia and amygdalae.	20558943
Airway structure, Asthma	Altered Intercellular Communication	Exposure to particulate matter (PM) outdoors can induce airway inflammation and exacerbation of asthma in adults.	20559007
Inflammation, Neoplasms	Altered Intercellular Communication	Several case reports have discussed the difficulty in differentiating junctional pseudomelanocytic nests as a result of lichenoid inflammation from a true melanocytic neoplasm.	20559116
Inflammation, Intraocular inflammation	Altered Intercellular Communication	In most cases of sterile intraocular inflammation after IVB, visual acuity returned to baseline, and intraocular inflammation rarely recurred with repeat IVB or intravitreal ranibizumab.	20559156
Inflammation, Carcinogenesis	Altered Intercellular Communication	Inflammation is postulated to play an important role in ovarian carcinogenesis.	20559705
Inflammation, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	The clinical diagnosis of bacterial-induced myocarditis was confirmed by specific radiological findings of inflammation using cardiac magnetic resonance imaging.	20559889
Inflammation, curcumin, Observation Method - Coagulation	Altered Intercellular Communication	Immune-mediated inflammation and coagulation are strictly linked, and coagulation activation has been described in CU patients as shown by the elevation of plasma prothrombin fragment F1+2 and, in severe cases, of d-dimer as well.	20561123
Inflammation, Primary malignant neoplasm, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Low-grade inflammation is thought to contribute to the development of cardiovascular disease (CVD), type-2 diabetes mellitus (T2D), cancer and mortality.	20561148
Inflammation	Altered Intercellular Communication	Biomarkers of inflammation may aid in risk prediction and enable early intervention and prevention of disease.	20561148
Inflammation, Deep thrombophlebitis	Altered Intercellular Communication	It is concluded that the DVT and inflammation are closely related, increased level of plasma CRP may be a predictor of DVT.	20561444
Inflammation, Observation Method - Coagulation, Deep thrombophlebitis	Altered Intercellular Communication	Interaction between inflammation and coagulation promote the incidence of DVT, which may be one of DVT pathogenesis.	20561444
Pain Distress Question, Inflammation, Edema	Altered Intercellular Communication	The VCSS 2 and 3 for pain, oedema and inflammation were found in 22%, 26% and 0% of C6 legs.	20561800
Disorder of vein, Pain Distress Question, Inflammation, Edema	Altered Intercellular Communication	Visible varicose veins, pain, oedema and inflammation were uncommon and most patients could maintain their usual activities despite advanced venous disease.	20561800
Cessation of life, Inflammation	Altered Intercellular Communication	PARP-1 is involved in the regulation of genomic integrity, transcription, inflammation, and cell death.	20561897
Inflammation, Hepatitis, Cardiomyopathies, Pneumonitis, CTCAE, kyphosis, Anemia, Dermatitis, Kidney Diseases	Altered Intercellular Communication	Here, we show that hPARP-1 mice exhibit impaired survival rates accompanied by reduced hair growth and premature development of several inflammation and age-associated pathologies, such as adiposity, kyphosis, nephropathy, dermatitis, pneumonitis, cardiomyopathy, hepatitis, and anemia.	20561897
allergic inflammation	Altered Intercellular Communication	Recent studies have associated osteopontin (OPN) with allergic inflammation; however, its role in human asthma remains unclear.	20562127
Traumatic injury, Kidney Diseases	Altered Intercellular Communication	We performed a secondary analysis of the "Inflammation and the Host Response to Injury" (Glue Grant) database to include adult blunt trauma patients without history of kidney disease.	20562612
Calcified (qualifier), Atheroma, Inflammation	Altered Intercellular Communication	Calcifications were stable over time, but 18F-FDG uptake changed in more than half of the patients, supporting the postulate that inflammation in atheroma is a waxing and waning inflammatory process.	20562727
Inflammation	Altered Intercellular Communication	Systemic inflammation caused by chronic periodontite in patients victims of acute ischemic heart attack.	20563468
Inflammation, Prostatic Intraepithelial Neoplasias	Altered Intercellular Communication	While Gleason scores remained relatively stable over time, reporting of prostate intraepithelial neoplasia (PIN) and inflammation increased.	20564087
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Seventy-two percent of the cases showed necrosis, often accompanied by acute, chronic, or granulomatous inflammation.	20564422
Inflammation, Fracture, Difficulty walking	Altered Intercellular Communication	The approach is applied to a cohort of elderly female hip fracture patients to estimate the prevalence of walking disability over time as a function of body composition, inflammation, and age.	20564729
Inflammation, Thrombosis	Altered Intercellular Communication	Isolated superior ophthalmic vein (SOV) thrombosis is a rare condition usually related to inflammation of the orbit or paranasal sinuses.	20565317
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Our results show that donor histology can affect disease recurrence, especially the grade of inflammation, fibrosis, and fatty degeneration.	20565366
Stomatitis, Stomach Carcinoma, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Gastric cancer can progress from a chronic inflammation of the gastric mucosa resulting from Helicobacter pylori infection that activates the inflammatory response of the host.	20565800
Intraocular inflammation, Complication Aspects	Altered Intercellular Communication	From 70-80% of positive untreated HIV patients develop ocular complications, with intraocular inflammation in more than half of them.	20566167
Intraocular inflammation, Opportunistic Infections, Neoplasms	Altered Intercellular Communication	Intraocular inflammation can be associated with opportunistic infections, tumours and as in our case, secondary to the HIV.	20566167
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Abdominal fat mass contributes to the systemic inflammation in chronic obstructive pulmonary disease.	20566396
ARCN1 gene, Inflammation	Altered Intercellular Communication	The contribution of abdominal fat mass to the systemic inflammation often present in COPD has not been examined yet.	20566396
ARCN1 gene, Inflammation	Altered Intercellular Communication	The aim of the present study was to investigate if abdominal fat mass contributes to the systemic inflammation in patients with moderate to severe COPD.	20566396
ARCN1 gene, Inflammation	Altered Intercellular Communication	Abdominal fat mass contributes to the systemic inflammation in COPD.	20566396
Ischemia, Hemorrhage, Adipose Tissue Atrophy, Necrosis, Fibrosis Assessment, Myositis, Infarction, Diabetic Cardiomyopathies	Altered Intercellular Communication	Diabetic myopathy encompasses a spectrum of diseases, including muscle inflammation, ischemia, hemorrhage, infarction, necrosis, fibrosis, and fatty atrophy.	20566817
Granulomatous inflammation	Altered Intercellular Communication	While granulomatous inflammation was a rare observation in North American cases, it was seen in the majority of cases worldwide.	20567913
Granulomatous inflammation	Altered Intercellular Communication	Patients with A. flavus were younger, demonstrated granulomatous inflammation, and pursued an indolent, clinically responsive course.	20567913
Airway structure, Asthma	Altered Intercellular Communication	Severe asthma occurs in a heterogeneous group of patients in whom symptoms and airway inflammation persist despite maximal antiasthma treatment.	20568377
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Subjects with the metabolic syndrome (MetS) have enhanced oxidative stress and inflammation.	20569506
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	In conclusion, a 12-week dietary fat modification did not affect the investigated markers of oxidative stress and inflammation among subjects with the MetS in the LIPGENE study.	20569506
Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Although it grows slowly and usually without symptoms, it may require excision because of inflammation, secondary infection, or, in rare cases, malignancy developing within the cyst.	20569540
Inflammation, Malignant Neoplasms, Uterine Corpus Sarcoma	Altered Intercellular Communication	Since malignancy is known to be associated with systemic inflammation which leads to hematological alteration, we compared the efficacy for the preoperative diagnosis of uterine sarcomas between the neutrophil to lymphocyte ratio (NLR) and serum CA-125 levels using a case-match comparison.	20570475
Squamous cell carcinoma of esophagus	Altered Intercellular Communication	Inflammation-based prognostic score and number of lymph node metastases are independent prognostic factors in esophageal squamous cell carcinoma.	20571271
Inflammation	Altered Intercellular Communication	The growing body of evidence linking inflammation and frailty in older people, an association that seems consistent across different frailty definitions, is therefore of great interest to research gerontologists.	20571864
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	The extent of hepatic inflammation and fibrosis was evaluated in these patients by examining liver biopsy specimens.	20572087
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	All 10 patients with significant hepatic inflammation and fibrosis were male and older than 25 years.	20572087
Cessation of life, Inflammation	Altered Intercellular Communication	Cox proportional hazards ratios were calculated both for death from diseases in which inflammation or oxidative stress was a predominant contributor and for cardiovascular mortality.	20573797
Inflammation, Herpes zoster disease, Exanthema	Altered Intercellular Communication	This is the first report defining the nature of the immune response in ganglia following herpes zoster and provides evidence for persistence of non-latency-associated viral antigen and inflammation beyond rash resolution.	20573825
Retinitis	Altered Intercellular Communication	The origin of the SDPs observable in SD-OCT is unknown, but they may represent migrating RPE cells or leukocytes, indicating a certain status of retinal inflammation.	20574019
Data types - Address	Altered Intercellular Communication	Although recent evidence suggests alterations in 5-HT neurotransmission in AD, it is not clear how hippocampal 5-HT innervation is modified.	20576032
Cystic Lesion, Sialorrhea	Altered Intercellular Communication	Some cystic lesions may be functioning and should therefore be screened for hormonal hypersecretion.	20576282
Inflammation, Hepatitis C	Altered Intercellular Communication	Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients.	20576307
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We also found that inflammation activity and fibrosis of the liver were significantly more severe in patients homozygous for the IL28 major allele (p=0.025 and 0.036, respectively).	20576307
Hepatitis C, Liver diseases	Altered Intercellular Communication	These results suggest that different cytokine profiles induced by the IL28 polymorphism resulted in different biochemical and inflammatory conditions during chronic HCV infection and contribute to the progression of liver diseases.	20576307
Idiopathic disease, Giant Cell Arteritis, Inflammation, Takayasu Arteritis	Altered Intercellular Communication	Giant cell arteritis, Takayasu arteritis, and Horton disease are rare, idiopathic diseases that cause chronic inflammation and obliteration of large arteries, mainly the aorta and its major branches.	20576654
Inflammation	Altered Intercellular Communication	We aimed to analyze whether markers of systemic inflammation can predict response to antibiotics in AECOPD.	20576731
Scleritis	Altered Intercellular Communication	Clinical records of 83 patients with scleritis who presented between 1998 and 2008 to the Ocular Inflammation Service of the Kyorin Eye Center, Tokyo, were reviewed.	20576778
Inflammation, Carcinogenesis	Altered Intercellular Communication	Variation in genes contributing to the host immune response may mediate the relationship between inflammation and prostate carcinogenesis.	20576793
Inflammation, Prostate carcinoma	Altered Intercellular Communication	The results of this study support a link between RNASEL and prostate cancer and suggest that the association may be mediated through inflammation.	20576793
Inflammation	Altered Intercellular Communication	The chronic inflammation is most probably owing to the chronic topical treatment of the patients and seems to be a significant risk factor for DS surgery failure.	20577105
Inflammation, Albuminuria, atherosclerotic	Altered Intercellular Communication	Increased MA in TT homozygous women might be explained by other mechanisms of albuminuria or inflammation than the atherosclerotic process.	20577224
Inflammation	Altered Intercellular Communication	Extraskeletal bone formation associated with inflammation preceding the osseous conversion usually begins in the first decade, predominantly in the head, neck, and shoulders.	20577760
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	Heparanase activity plays a decisive role in biological processes associated with remodeling of the extracellular matrix (e.g., cancer metastasis, angiogenesis, and inflammation).	20578081
Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation has been shown to be a major component in the pathophysiology of acute coronary syndrome (ACS).	20579652
Inflammation, atherosclerotic	Altered Intercellular Communication	Longitudinal studies are needed to assess whether this increase is due to inflammation or a higher atherosclerotic burden.	20579652
Inflammation	Altered Intercellular Communication	Recently, immune response and inflammation were suggested to play certain roles in the development and complications of T2DM.	20580039
Minimal Disseminated Disease, Unipolar Depression, Alcoholic Intoxication, Chronic	Altered Intercellular Communication	Alteration of glutamatergic neurotransmission in the prefrontal cortex (PFC) may contribute to the pathophysiology of alcoholism and major depressive disorder (MDD).	20580095
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Relationship between portal chronic inflammation and disease severity in paediatric non-alcoholic fatty liver disease.	20580331
Fibrosis, Liver, Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	The non-alcoholic steato-hepatitis Clinical Research Network has recently shown that portal chronic inflammation is associated with liver fibrosis in American children with non-alcoholic fatty liver disease.	20580331
Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	We tested whether the portal chronic inflammation-fibrosis association was present in a series of Italian children with non-alcoholic fatty liver disease.	20580331
Nonalcoholic Steatohepatitis, Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Non-alcoholic fatty liver disease and portal chronic inflammation were diagnosed using the non-alcoholic steato-hepatitis Clinical Research Network criteria.	20580331
Nonalcoholic Steatohepatitis, Inflammation	Altered Intercellular Communication	Two children had no portal chronic inflammation, 84 had mild and 58 more than mild portal chronic inflammation according to the non-alcoholic steato-hepatitis Clinical Research Network criteria.	20580331
Inflammation	Altered Intercellular Communication	Children with no or mild portal chronic inflammation had the same clinical features of those with more than mild portal chronic inflammation except for insulin resistance, which was greater.	20580331
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	There was no association between steatosis, lobular inflammation, ballooning, fibrosis and portal chronic inflammation.	20580331
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	We were not able to confirm the existence of a clinico-pathological association between portal chronic inflammation and disease severity in a series of Italian children with non-alcoholic fatty liver disease.	20580331
Inflammation, Arthritis	Altered Intercellular Communication	We have investigated associations between angiogenesis, inflammation and neurovascular growth factor expression at the osteochondral junction in human arthritis.	20581375
Subject Disease Milestones Domain, Inflammation, Trigone of bladder, Squamous metaplasia	Altered Intercellular Communication	Two, partly overlapped, pathologic patterns prevailed: (a) nonkeratinizing squamous metaplasia (SM) found in 64% of the patients, including 2 of 4 men; (b) mucosal inflammation of the bladder base/trigone that extended-especially among male patients-to the proximal urethra (64% of the patients).	20581654
Inflammation, Adenocarcinoma of colon	Altered Intercellular Communication	On histopathologic examination, the patient had nonspecific, active, chronic inflammation of the ileal mucosa, consistent with backwash ileitis, and colonic adenocarcinoma.	20581781
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Despite additional treatment with leukocytapheresis, the backwash ileitis progressed, with increased severity of mucosal inflammation and extensive erosions, 20 cm proximal to the primarily affected site of the ileum on repeat colonoscopy 2 months later.	20581781
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The following histological features were associated with each other: prominent inflammation, anastomosing sheets, absence of fibrosis, absence of infiltrative margin and absence of gland formation.	20581807
Inflammation, Neoplasms	Altered Intercellular Communication	Prominent inflammation and anastomosing sheets in at least 30% of the tumour were associated with a better prognosis on univariate analysis.	20581807
Inflammation, Autoimmune reaction	Altered Intercellular Communication	Th17 cells play an important role in inflammation in human autoimmune arthritides, both at the onset and in established disease.	20583102
Inflammation, Fournier Gangrene	Altered Intercellular Communication	We report a 58-year-old man with rapidly progressive, gas-producing, necrotizing inflammation in the retroperitoneum, complicated with genital involvement resembling Fournier gangrene.	20583955
ACSM3 gene, Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Brain parenchyma is generally not affected by the disease; however, histological investigation suggested that inflammation of the dura caused damage to superior hypophyseal artery resulting in SAH and apoplexy in the anterior lobe of the pituitary gland.	20585819
Bacteremia, Inflammation, Fever, CTCAE	Altered Intercellular Communication	Six patients had a fever, nine had inflammation at the hemodialysis access site, and six of them had concomitant bacteremia.	20585966
palladium	Altered Intercellular Communication	Our results support the hypothesis that serotonergic neurotransmission is decreased in untreated PD and suggest that a low serotonergic activity may be related to the dopamine pathology in PD.	20586535
Inflammation, Lacrimation	Altered Intercellular Communication	One case of membrane tearing resulted from previous inflammation in the maxillary sinus, and the other case of membrane tearing was caused by application of excessive hydraulic pressure.	20586782
Gastrointestinal inflammation	Altered Intercellular Communication	However, the relationship between intestinal inflammation and miRNA expression remains unclear.	20586854
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Upregulated miRNA may be responsible for the development of intestinal inflammation in UC.	20586854
Fibrosis, Liver, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Analyze the age, sex, grade of liver inflammation and stage of liver fibrosis among patients with chronic HBV carriers (n = 58) and non-active HBsAg carriers (n = 32), and compare the grade of liver inflammation and stage of liver fibrosis in different groups according to age, ALT levels and with/without HBeAg.	20587313
Fibrosis, Liver, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	(3) As to the grade of liver inflammation and the stage of liver fibrosis, significant differences existed between the groups with higher level of serum ALT (20-40 U/L) and lower level ( is less than or equal to 20 U/L) (Chi-square = 7.827, P = 0.008; Chi-square = 14.303, P = 0.001), and similar results also existed between elder group (more than 40) and younger group (is less than or equal to 40) (Chi-square = 10.949, P = 0.001; Chi-square = 21.271, P less than 0.01); (4) Among the chronic HBV carriers, significant differences existed in grade of liver inflammation between groups with HBeAg positive and negative patients (Chi-square = 10.275, P = 0.002), and the latter was more aggravated; however, there was no difference in stage of liver fibrosis between them (Chi-square test = 3.457, P = 0.178).	20587313
Inflammation, Snoring	Altered Intercellular Communication	We therefore investigated whether snoring may mediate the increased vascular risk directly through increased inflammation as indicated by HsCRP levels or if other determinants predominated in a large older Chinese population.	20587368
Inflammation, Vascular Diseases	Altered Intercellular Communication	Our results showed that snoring frequency did not have an independent effect on inflammation after adjusting for adiposity, and may thus contribute to vascular disease through alternative mechanisms.	20587368
Gastrointestinal inflammation	Altered Intercellular Communication	In 48 MDCT/MR enterography examinations, active disease was demonstrated: abscesses (n = 11), fistulas (n = 13), stenoses (n = 23) and/or intestinal inflammation (n = 38).	20588038
Inflammation, Pain Distress Question	Altered Intercellular Communication	The patient attended medical consultation after two months of inflammation and pain in her right eye.	20589334
Inflammation, Takayasu Arteritis	Altered Intercellular Communication	Takayasu's arteritis (TA) is a chronic inflammation that frequently involves the aorta and its major branches.	20589520
Interstitial inflammation	Altered Intercellular Communication	Interstitial inflammation (i1-i3) was present in all 17 biopsies.	20590689
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Further, it appears that MUC4 expression in the skin may be modulated by chronic inflammation and the presence of an adjacent cutaneous malignancy in certain cases.	20591909
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Recent data suggest a link between chronic inflammation, angiogenesis, and the development of cancer.	20592377
Vaginitis, Bacterial Vaginosis, Inflammation, Inflammatory	Altered Intercellular Communication	Subjects were classified into 3 groups: no vaginitis if symptoms were absent and examination results was normal; common vaginitis (CV) if microscopic examination revealed yeast, bacterial vaginosis, or trichomonads; or inflammatory vaginitis (IV) if examination revealed inflammation and immature squamous cells but no pathogens.	20592549
Inflammation, Calcinosis, Atherosclerosis	Altered Intercellular Communication	Further, lipoxygenase pathway SNPs that were associated with measures of atherosclerosis were associated with markers of inflammation (CRP, ICAM-1) and calcification (MGP).	20592751
Inflammation, Carcinogenesis	Altered Intercellular Communication	Cyclooxygenase-2 (COX-2) is involved in inflammation and carcinogenesis.	20592893
Inflammation	Altered Intercellular Communication	A profile was identified in these genes that indicated a higher level of metabolism in good responding patients, which indirectly can be connected to increased inflammation.	20593016
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The microdialysis method was applied to the human knee joint with osteoarthritis (OA) in order to reveal changes in biochemical markers of cartilage and inflammation, intraarticularly and in the synovium, in response to a single bout of mechanical joint loading.	20594330
Inflammation, Impaired cognition	Altered Intercellular Communication	Role of lipoproteins and inflammation in cognitive decline: do they interact?	20594617
Inflammation, Nasal obstruction present finding, Osage language	Altered Intercellular Communication	In conclusion, nasal obstruction of OSA patients on CPAP treatment is inflammatory in origin and the addition of heated humidification decreases nasal resistance and mucosal inflammation.	20595158
Refractory anemias	Altered Intercellular Communication	These results suggest that LILRA3 may play a role in chronic inflammatory conditions such as RA.	20595277
Inflammation, Disorder of tendon	Altered Intercellular Communication	The cellular mechanisms of tendinopathy remain unclear particularly with respect to the role of inflammation in early disease.	20595553
Coronary Artery Disease	Altered Intercellular Communication	Circulating levels of vascular and inflammation-associated microRNAs are significantly downregulated in patients with coronary artery disease.	20595655
Cushing Syndrome	Altered Intercellular Communication	She presented with signs and symptoms of hypercortisolism and hormonal testing was indicative for pituitary-dependent Cushing' s syndrome.	20595779
Inflammation, Prehypertension	Altered Intercellular Communication	Prehypertension (PreHT) and low-grade inflammation are both known to be related to the incidence of cardiovascular events.	20596037
Inflammation, CAPN5 gene	Altered Intercellular Communication	Aberrant T-cell-mediated processes may underlie ADNIV, and therapeutics directed at T cells may better manage inflammation in these patients.	20596252
Chronic liver disease, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	In conclusion, we found that HCV-related HCC in the elderly occurred against a background of chronic liver disease with mild inflammation and fibrosis.	20596605
Inflammation, pseudomembranous colitis, Paralytic Ileus	Altered Intercellular Communication	The enterocytic detachment and bowel inflammation provoke C. difficile-associated diarrhoea (CDAD) sometimes developing into severe pseudomembranous colitis (PMC) and paralytic ileus.	20597000
Inflammation	Altered Intercellular Communication	As degradation of hyaluronic acid by hyaluronidase into low molecular weight hyaluronic acid (LMW-HA) is associated with inflammation and Matrix Metalloproteinase (MMP)-9 activity, we hypothesized that hyaluronic acid metabolism is increased in plaques with unstable characteristics like large lipid core, high number of macrophages, MMP-9 activity, low collagen and smooth muscle cell content.	20597964
Inflammation	Altered Intercellular Communication	Myeloperoxidase (MPO) is a hemoprotein that is released during inflammation and may lead to irreversible protein and lipid modification, increasing levels of oxidized low density lipoprotein, and promoting athrogenesis.	20597992
Inflammation, Diabetes Mellitus, Atherosclerosis	Altered Intercellular Communication	The pathogenesis of diabetes and atherosclerosis is linked through inflammation.	20598696
Nocturia, Depression, CTCAE	Altered Intercellular Communication	To assess the relationship between nocturia and depression, two inflammatory conditions that affect a significant number of men worldwide.	20599253
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Angiopoietin-2 has been reported to regulate the inflammation process, which is associated with recurrence of stroke.	20599737
Alzheimers Disease", Data types - Address, Nerve Degeneration	Altered Intercellular Communication	Oxidative stress is implicated in the pathogenesis of Alzheimer's disease (AD) causing neurodegeneration and decreased monoamine neurotransmitters.	20600435
Inflammation, Demographics Domain	Altered Intercellular Communication	To determine whether IL-18 is involved in the inflammation of DM and PM.	20601655
Inflammation, Heart failure, Anemia, hepcidin	Altered Intercellular Communication	In this group of patients with combined heart and renal failure and anaemia, increased hepcidin levels were associated with markers of iron load and not with markers of inflammation.	20601671
Inflammation, hepcidin	Altered Intercellular Communication	In our group hepcidin seems to reflect iron load and response to EPO rather than inflammation and EPO resistance.	20601671
Communicable Diseases, Inflammation, Myocarditis, CTCAE 5.0, Myocardium	Altered Intercellular Communication	Myocarditis is defined clinically as inflammation of the heart muscle, which can be caused by infectious agents, toxins or immunologic reactions.	20601856
Alzheimers Disease", Inflammation, Data types - Address, Disease	Altered Intercellular Communication	Alzheimer disease (AD) and age-related ocular diseases are characterized by inflammation and accumulation of insoluble proteins.	20602326
Unilateral, Calcinosis, Acute inflammation	Altered Intercellular Communication	The sequence of events, unilaterality, and pathologic findings suggest secondary calcification, which could have been related to severe postoperative inflammation and associated blood-aqueous barrier breakdown.	20602329
Granulomatous inflammation, Infection of kidney	Altered Intercellular Communication	XGPN is a rare type of renal infection characterised by granulomatous inflammation with giant cells and foamy histiocytes.	20602802
Venous Thromboembolism	Altered Intercellular Communication	Single nucleotide polymorphisms in inflammation-related genes are associated with venous thromboembolism.	20603037
Inflammation, vinyltriethoxysilane	Altered Intercellular Communication	Therefore, polymorphisms in genes involved in inflammation may influence susceptibility towards VTE.	20603037
Biliary Anastomotic Leakage, Acalculous Cholecystitis	Altered Intercellular Communication	Inflammation of the gallbladder caused by calculous cholecystitis, which leads to biliary leakage and erodes the right hepatic artery, could have been the cause.	20603093
Refractory anemias, Inflammation	Altered Intercellular Communication	Our results therefore provide a new insight into the IL-27-activated immunopathological mechanisms mediated by distinct intracellular signal transductions in joint inflammation of RA.	20604932
Inflammatory abnormality of the eye	Altered Intercellular Communication	To evaluate how smoking affects the time to disease quiescence and time to disease recurrence in patients with ocular inflammation.	20606023
Herpes Zoster Ophthalmicus, Inflammatory abnormality of the eye	Altered Intercellular Communication	Among 2676 patients with active ocular inflammation, smokers were more likely to have bilateral ocular disease and poorer visual acuity on presentation compared with non-smokers and previous smokers.	20606023
Low Vision, Inflammatory abnormality of the eye	Altered Intercellular Communication	Smoking was associated with an increased likelihood of bilateral ocular inflammation and reduced vision upon presentation, and an increased risk of recurrence compared with not smoking.	20606023
Inflammatory abnormality of the eye	Altered Intercellular Communication	These results suggest that patients with ocular inflammation should be counselled to stop smoking as part of routine management.	20606023
Inflammation, Acidosis, Ischemia	Altered Intercellular Communication	Systemic acidosis and subsequent inflammation after ischemia reperfusion may play an important role in the development of VT/VF.	20606327
Inflammation, Observation Method - Coagulation, Adult Glioblastoma	Altered Intercellular Communication	Circulating markers of angiogenesis, inflammation, and coagulation in patients with glioblastoma.	20607353
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation, angiogenesis, and coagulation are linked to the development of cancer.	20607353
Inflammation, Adult Glioblastoma	Altered Intercellular Communication	All inflammation markers, F1 + 2, ETG, VEGF and sVEGFR-1, were significantly elevated in glioblastoma patients.	20607353
Inflammation	Altered Intercellular Communication	Thrombomodulin (TM) plays a role in coagulation, inflammation, and cell adhesion.	20607726
Asthmatic Airway Remodeling	Altered Intercellular Communication	Human bronchial epithelial (HBE) cells contribute to asthmatic airway inflammation by secreting cytokines, chemokines, and growth factors, including interleukin (IL)-6, IL-8 and transforming growth factor (TGF) b1, all of which are elevated in asthmatic airways.	20607798
Airway structure	Altered Intercellular Communication	Understanding the mechanism of aberrant pro-inflammatory cytokine production in asthmatic airways will allow the development of alternative ways to control airway inflammation.	20607798
Airway structure, Hypersensitivity	Altered Intercellular Communication	We speculated that IL-33 elevation is responsible for the maintenance of airway inflammation and hypersensitivity.	20608085
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	[Complex analsis of association of inflammation genes with myocardial infarction].	20608170
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Carriage frequencies of alleles and genotypes of functionally important polymorphous loci of some inflammation genes: proinflammatory cytokines genes IL-6, LTA and TNF, anti-inflammatory cytokine gene TGFB1 and CC chemokine receptor 5 gene CCR5 were analyzed in the patients with myocardial infarction (MI) of Russian ethnic descent (199 cases) and in the control group of the same ethnic descent (142 controls).	20608170
Guillain-Barre Syndrome, Paresis, Paralysed, Illness (finding)	Altered Intercellular Communication	Guillain-Barre syndrome, a randomly acquired inflammatory condition that can lead to progressive muscle weakness and paralysis, is a rare presentation in emergency departments, and differentiating its early stages from common viral illnesses can be difficult.	20608399
Inflammation, Lymphoma	Altered Intercellular Communication	Lymphoma was noted in 7 individuals and suppurative inflammation in 5.	20608767
ARCN1 gene, Inflammation, Malnutrition	Altered Intercellular Communication	Systemic inflammation has been suggested as one of the mechanisms of malnutrition in COPD.	20609004
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Low BMI was associated with the severity of emphysema and systemic inflammation reflected by elevated a1-AT level.	20609004
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Despite adequate erythropoiesis-stimulating agent (ESA) supplementation, some ESRD patients still have suboptimal hemoglobin levels, and iron deficiency and inflammation are recognized as the two most common causes.	20609184
Refractory anemias, Rheumatoid Arthritis, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	The purpose of this study was to investigate the profile of histone deacetylase (HDAC) expression in the synovial tissue of rheumatoid arthritis (RA) compared with that of normal control and osteoarthritis (OA), and to examine whether there is a link between HDAC activity and synovial inflammation.	20609223
Inflammation, Lymphadenitis	Altered Intercellular Communication	Cases of inflammation of the upper airway including the oral cavity, laryngopharynx, palate tonsil and salivary gland, and cases of lymphadenitis were investigated.	20609540
Parotitis, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	The presence of diabetes mellitus is associated with deep neck infection, aggravating parotitis and wide spread of inflammation.	20609540
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation has been implicated in the pathogenesis of postoperative atrial fibrillation (AF).	20609593
Inflammation	Altered Intercellular Communication	Postmortem examination of arteries showed no active inflammation.	20609853
Traumatic injury, Obesity	Altered Intercellular Communication	Obesity, like multiple trauma, is associated with an inflammatory condition that leads to an immunodeficient state.	20610250
Inflammation, Obesity, Atherosclerosis	Altered Intercellular Communication	Cathepsin S has been suggested provide a mechanistic link between obesity and atherosclerosis, possibly mediated via adipose tissue-derived inflammation.	20610597
Inflammation	Altered Intercellular Communication	The scrotum ruptured by itself, and the inflammation rapidly spread to the right inguinal area on 19 April.	20610927
Acute inflammation	Altered Intercellular Communication	In addition, one patient demonstrated modest acute neutrophilic inflammation with focal endothelial proliferation.	20614301
Rheumatoid Arthritis, Inflammation, Comorbidity, Cardiovascular Diseases	Altered Intercellular Communication	Prevalence and predictive factors of comorbidity in rheumatoid arthritis patients monitored prospectively from disease onset up to 20 years: lack of association between inflammation and cardiovascular disease.	20615160
Gastroesophageal reflux disease, Obesity	Altered Intercellular Communication	Gastroesophageal reflux disease (GERD) may link the obesity epidemic to an array of adverse health outcomes including chronic esophageal inflammation and, consequentially, to pathophysiological changes of the esophagus.	20615162
Hyperglycemia, Inflammation	Altered Intercellular Communication	Critical illness is commonly complicated by hyperglycaemia caused by mediators of stress and inflammation.	20615210
Joining Organizations with Leading Technologies, Nuchal Rigidity, Headache, Meningitis	Altered Intercellular Communication	The design was a double-blind, cross-sectional analysis of consecutive patients, independently comparing signs of meningeal inflammation (nuchal rigidity, head jolt accentuation of headache, Kernig's sign and Brudzinski's sign) elicited by internal medicine residents against an established reference standard (cerebrospinal fluid white cell count >5 white cells/mL).	20615607
Meningitis	Altered Intercellular Communication	Physical signs of meningeal inflammation do not help clinicians rule in or rule out meningitis accurately.	20615607
Inflammation	Altered Intercellular Communication	Cytoplasmic accumulation of mutant SOD1 was sensed by an ASC containing inflammasome and antagonized by autophagy, limiting caspase-1-mediated inflammation.	20616033
Inflammation, Meckel Diverticulum, Diverticulum	Altered Intercellular Communication	One patient had duplication of (double) Meckel's diverticulum without any inflammation in both the diverticulae.	20616416
Inflammation, Gangrene	Altered Intercellular Communication	Histopathological examination of these specimens confirmed 4 cases with inflammation; 2, with gangrene; and 1, with ulcerated gastric mucosa in the MD.	20616416
Cessation of life, Inflammation	Altered Intercellular Communication	Higher levels of IL-6 may reflect a chronic low-level systemic inflammation prospectively increasing the risk of death in the elderly.	20617391
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	It is hypothesized that the restoration of normal menses was caused by reduced inflammation in the ovarian tissue and supports the hypothesis that the gut immune system can influence autoimmune disease and inflammation.	20618099
Refractory Cytopenia of Childhood, Renal Cell Carcinoma Pathway	Altered Intercellular Communication	This cytokine is a critical mediator of the Th1/Th2 balance and apoptosis potential and involved in the process of inflammation-mediated carcinogenesis in human organs, including renal cell carcinoma (RCC).	20618516
Inflammation, Herpes simplex type 2 infection	Altered Intercellular Communication	A 34-year-old man presented with a recurring painful inflammation of his left middle finger, caused by a herpes simplex type 2 infection.	20619012
Acute inflammation, Carcinoid, Goblet Cell	Altered Intercellular Communication	However, histological examination revealed a small goblet cell carcinoid, histological group C, with acute inflammation.	20619032
Inflammation, Fibrosis Assessment, Pulmonary Emphysema, Pulmonary Fibrosis	Altered Intercellular Communication	To approach the relationships among inflammation, immune response, and fibrosis in combined pulmonary fibrosis and emphysema (CPFE) through the observation of distributions of lymphocyte subtypes, the variation of Pro-collagen III N-terminal peptide (PIIINP) expression and the severity of pulmonary fibrosis (PF) in CPFE.	20619092
Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	The CPFE group showed significant inflammation predominated by T-lymphocytes, especially CD8+; T-lymphocyte, as compared with the IPF and control groups, hence pointing to the fact that a novel anti-lymphocytes and immune regulation strategy may be useful for disease intervention.	20619092
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Systemic inflammation and the metabolic syndrome among middle-aged community volunteers.	20619428
Inflammation	Altered Intercellular Communication	Recent evidence suggests that markers of systemic inflammation may be included in the definition of the syndrome and play some role in its pathogenesis.	20619428
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Inflammation was positively associated with this common factor, accounting for 54% of its variance and partially mediating statistical aggregation of the component factors comprising the metabolic syndrome.	20619428
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The selenoprotein S (SELS) is a putative receptor for serum amyloid A, and recent studies have suggested that SELS may be a link between type 2 diabetes mellitus and inflammation.	20619427
Inflammation, Cellulitis, Infection, Necrosis	Altered Intercellular Communication	catheter-related soft tissue infections begin with local skin and soft tissue inflammation, which can progress to cellulitis or even tissue necrosis requiring aggressive surgical treatment.	20619497
Acute Coronary Syndrome	Altered Intercellular Communication	A comparative study of biomarkers for risk prediction in acute coronary syndrome-Results of the SIESTA (Systemic Inflammation Evaluation in non-ST-elevation Acute coronary syndrome) study.	20619836
Inflammation	Altered Intercellular Communication	ADMA may serve as a marker of systemic inflammation and may reflect functional immobility in AS.	20620092
Inflammation, Hypoxia, Anemia, hepcidin	Altered Intercellular Communication	Hepcidin, a small defensin-like peptide produced by hepatocytes, is modulated in response to anemia, hypoxia, or inflammation.	20620527
Renal Insufficiency, Inflammation, hepcidin, Anemia	Altered Intercellular Communication	Elevated hepcidin levels in heart transplant recipients may be due to low-grade inflammation, which is frequently encountered in this population, as well as probably to impaired renal function, but it does not seem to be a major pathogenic factor for anemia among this population.	20620527
Inflammation	Altered Intercellular Communication	This inflammation concerned the arteries of the deep dermis and of the superficial hypodermis.	20620576
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Markers of inflammation in men with small abdominal aortic aneurysm.	20620767
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Markers of inflammation and fibrin turnover are elevated in individuals with a large (>55 mm) abdominal aortic aneurysm (AAA).	20620767
Inflammation	Altered Intercellular Communication	Thoracic, abdominal and sinus computed tomographic scan was normal and bronchoscopy showed a non specific mucosa inflammation.	20621396
Inflammation	Altered Intercellular Communication	We propose that this eventually triggers inflammation and the EGFRI rash.	20621734
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Serine/threonine protein kinase 11 (STK11) and phosphatase tensin homolog deleted on chromosome 10 (PTEN) link insulin sensitivity and metabolic signaling to inflammation and other hormonal factors and colorectal cancer.	20622004
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Serine/threonine protein kinase 11 (STK11) and phosphatase tensin homolog deleted on chromosome 10 (PTEN) link insulin sensitivity and metabolic signaling to inflammation and other hormonal factors and colorectal cancer.	20622004
Inflammatory Bowel Diseases, Rheumatoid Arthritis, Pyoderma Gangrenosum, Hematologic Neoplasms	Altered Intercellular Communication	Pyoderma gangrenosum is an inflammatory condition of the skin commonly associated with inflammatory bowel disease and rheumatoid arthritis, but also associated with various hematological malignancies.	20622285
palladium	Altered Intercellular Communication	The relationship between the malnutrition-inflammation complex syndrome and high levels of some adipokines in peritoneal dialysis (PD) patients is still unclear.	20624111
Inflammation, Body Weight, Overweight	Altered Intercellular Communication	The purpose of this study was to investigate the levels of plasma adipokines and inflammation and oxidative stress markers in overweight and normal weight PD patients.	20624111
palladium, Inflammation	Altered Intercellular Communication	Markers of oxidative stress and inflammation were also higher in the PD group.	20624111
Inflammation, Overweight	Altered Intercellular Communication	The statistical analysis indicated that there were no differences in oxidative stress, inflammation and ADMA concentration between the lean and overweight PD patients.	20624111
palladium, Inflammation	Altered Intercellular Communication	The severity of chronic inflammation and oxidative stress were not related to BMI in PD patients.	20624111
Inflammation	Altered Intercellular Communication	It is characterized by inflammation and cellular infiltration of small vessels and presence of anti-neutrophil cytoplasmic antibodies (ANCA).	20624360
Kidney Failure, Chronic, Inflammation, Comorbidity	Altered Intercellular Communication	Testosterone deficiency is a common finding among male ESRD patients, and it is independently associated with inflammation, cardiovascular co-morbidity and outcome.	20624775
Inflammation, Disease remission, Atherosclerosis, Corneal Endothelial Cell Loss, Aortic Valve Stenosis, Calcinosis	Altered Intercellular Communication	Calcific aortic valve stenosis is an active disease process characterized by mechanical stress, endothelial damage, lipid accumulation, inflammation, synthesis of extracellular matrix proteins, and calcification, reminiscent of atherosclerosis in many aspects.	20625307
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Moreover, the severity of lobular inflammation or fibrosis did not influence the MRI measurements.	20625773
Inflammation, Non-alcoholic Fatty Liver Disease, Hyperlipidemia	Altered Intercellular Communication	The effect of genotype on NAFLD is probably mediated through chronic low-grade systemic inflammation rather than through dislipidemia.	20625834
Gilles de la Tourette syndrome	Altered Intercellular Communication	The analysis of selected neurotransmitter concentrations in serum of patients with Tourette syndrome.	20625961
Gilles de la Tourette syndrome	Altered Intercellular Communication	Metabolic disturbances of excitatory and inhibitory neurotransmitters are implicated in pathogenesis of Tourette syndrome (TS).	20625961
Inflammation	Altered Intercellular Communication	Since oxidative stress and inflammation impair insulin actions as well, it is conceivable that AGEs may play some role in insulin resistance.	20626403
Inflammation, Thrombosis, deficiency aspects	Altered Intercellular Communication	Because inflammation can potentially mask deficiency states or mimic an increased risk of thrombosis, FVIII, VWF and Fg determinations should be supplemented by measurements of hsCRP.	20627205
Inflammation, Myopathy, Myelitis, Transverse	Altered Intercellular Communication	Transverse myelitis, which is characterised by bilateral inflammation of the spinal cord and myelin destruction, is associated with myopathy, autonomic dysreflexia and pulmonary aspiration.	20627694
Inflammation, Sleep Apnea, Obstructive, Obesity	Altered Intercellular Communication	Obstructive Sleep Apnea Syndrome (OSAS) is associated with inflammation, but obesity may be a confounding factor.	20628509
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	OSAS patients had significantly higher TNF-alpha levels (P < .001) while no other difference in the examined inflammation markers was recorded between groups.	20628509
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Obese OSAS patients have elevated TNF-alpha levels compared to BMI-matched controls, suggesting a role of OSAS in promoting inflammation, possibly mediated by TNF-a.	20628509
Inflammation	Altered Intercellular Communication	Fiberoptic bronchoscope-guided biopsy of the mass on two occasions showed acute-on-chronic inflammation.	20628853
Inflammation	Altered Intercellular Communication	External root resorption can be found in the furcation area of mandibular teeth as a result of chronic inflammation.	20629542
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Chronic inflammation is linked to type 2 diabetes (T2DM), so we investigated correlations between obesity, blood glucose levels, and inflammation in T2DM patients.	20630610
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In unmethylated UC-background mucosa, DAPK protein expression increased with activity of UC-associated inflammation, suggesting a protective role of the pro-apoptotic DAPK during the chronic inflammatory process of UC.	20630662
Inflammation, Failure (biologic function)	Altered Intercellular Communication	The major causes of failure were unsuccessful initial healing and replacement root resorption with periodontal inflammation.	20630706
Communicable Diseases, Inflammation, Immunocompromised Host, Malignant Neoplasms	Altered Intercellular Communication	Overall diagnostic efficacy between immunocompetent and immunocompromised patients was comparable (P = .2); however, detection of infection or inflammation in individual groups was lower compared with detection of malignancy (P = .002 and P = .06, respectively).	20630827
Inflammation	Altered Intercellular Communication	None of the parameters correlated with disease severity and markers of systemic inflammation.	20631813
AURKAIP1 gene, Inflammation	Altered Intercellular Communication	Prominent intra-islet inflammation and decreased vascularity in AIP may contribute to diabetogenic effects.	20632032
Inflammation, Atrophic	Altered Intercellular Communication	We also studied foci with partial or complete atrophy without inflammation.	20632094
Inflammatory Bowel Diseases, Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Serum was collected from 191 patients with IBD (85 with ulcerative colitis (UC) and 106 with CD), 29 cases with other causes of intestinal inflammation and 96 healthy controls.	20632100
Autistic Disorder	Altered Intercellular Communication	Dysfunction of cerebral cortex in autism is thought to involve alterations in inhibitory neurotransmission.	20632321
Inflammation, Hypoxia, Varicosity	Altered Intercellular Communication	Pathogenic mechanisms in varicose vein disease: the role of hypoxia and inflammation.	20632821
Inflammation, Impaired cognition	Altered Intercellular Communication	After adjustment for demographics, chronic health conditions, health status, and inflammation, the association between reduced hemoglobin and cognitive impairment was attenuated and no longer significant, including among those with hemoglobin >=2 g/dL below the WHO threshold (odds ratio 1.39, 95% confidence interval = 0.94-2.04).	20634281
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Regulatory T lymphocytes (Treg) play a fundamental importance in modulating the relative balance between inflammation and immune tolerance, and alterations of these cells are observed in inflammatory diseases.	20634592
Inflammation	Altered Intercellular Communication	A state of low-grade systemic inflammation may underlie this constellation of risk factors.	20634647
Inflammation, Periodontal Diseases	Altered Intercellular Communication	Chronic inflammatory conditions, such as periodontal disease, may contribute to systemic inflammation and development of MetS.	20634647
Inflammation, Alveolar Bone Loss, Periodontal Diseases, ETV3 wt Allele	Altered Intercellular Communication	The association of alveolar bone loss to MetS is consistent with the hypothesis that destructive periodontal disease may contribute to the development of MetS and elevations in systemic inflammation.	20634647
Inflammation, Periodontal Diseases, ETV3 wt Allele	Altered Intercellular Communication	Longitudinal studies are necessary to clarify the role of periodontal disease in the development of MetS and conditions associated with chronic inflammation.	20634647
Inflammation, Periodontal Diseases	Altered Intercellular Communication	Chronic inflammatory conditions, such as periodontal disease, may contribute to systemic inflammation and development of MetS.	20634647
allergic inflammation	Altered Intercellular Communication	The demonstration of proinflammatory neuropeptides in NAL and suppression of their release after allergen challenge caused by a topical corticosteroid suggest a role for neuropeptides in allergic inflammation.	20635787
Airway structure	Altered Intercellular Communication	Leukotrienes and isoprostanes are biomarkers of airway inflammation and oxidative stress that can be detected in exhaled breath condensate (EBC).	20635789
Airway structure	Altered Intercellular Communication	Our findings suggest that EBC is a noninvasive method for airway inflammation and oxidative stress assessment.	20635789
Tissue damage, Inflammation, Ulcer	Altered Intercellular Communication	Our study identifies PG as a paradigm of neutrophil-mediated inflammation, with proinflammatory cytokines/chemokines and MMPs acting as important effectors for the tissue damage, particularly in ulcerative and bullous PG where damage is stronger.	20636397
Inflammation, Observation Method - Coagulation, Neoplasms	Altered Intercellular Communication	Microvesicles are involved in different pathological processes such as inflammation, coagulation and tumor progression.	20637189
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	By this method we investigated the association of inflammation with platelet activation in patients with nonvalvular atrial fibrillation (NVAF).	20637189
Inflammation	Altered Intercellular Communication	Inflammation may be involved in the activation of platelets in NVAF.	20637189
Inflammation	Altered Intercellular Communication	Diffuse type of inflammation was associated with T2DM.	20638146
Inflammation, Chief complaint (finding), Diabetes Mellitus	Altered Intercellular Communication	Inadequately controlled diabetes with Candida-associated DS was linked to a high incidence of an extensive type of inflammation, oral complaints and associated conditions.	20638146
Vasculitis	Altered Intercellular Communication	Recent studies suggest that C-reactive protein (CRP) reflects vascular wall inflammation and can predict adverse events.	20638228
Disability, Inflammation, Congenital Abnormality	Altered Intercellular Communication	Chronic inflammation can lead to permanent structural changes, deformity and disability.	20638271
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	In patients with abdominal aortic aneurysms (AAA), the changes in nitric oxide metabolism in close association with inflammation, appear to play a leading role in the aetiopathology of this disease, although it is still not clear.	20638617
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The positive correlation between the FMDB and CRP supports the hypothesis that inflammation and endothelial dysfunction are processes associated with the physiopathology of AAA and vary with their growth.	20638617
Hypoxia	Altered Intercellular Communication	We analyzed the relationship between aging and hypoxia by examining oxidative stress and inflammation-related cytokines.	20639132
vascular inflammations, Microvascular Angina	Altered Intercellular Communication	Increased oxidative stress and vascular inflammation have been demonstrated in patients with cardiac syndrome X (CSX).	20639239
Parkinson Disease, Inflammation, palladium	Altered Intercellular Communication	Interestingly, both inflammation and oxidative stress, which play a role in the etiology of Parkinson's disease (PD), may accelerate telomere shortening.	20639300
Cerebrovascular accident	Altered Intercellular Communication	Carotid plaque inflammation is associated with cerebral microembolism in patients with recent transient ischemic attack or stroke: a pilot study.	20639303
Inflammation	Altered Intercellular Communication	These findings strengthen the notion that embolic events distal to carotid stenoses are related to plaque inflammation, and FDG PET may be useful in the investigation of culprit carotid lesions.	20639303
Inflammation, Depression, CTCAE, AUTONOMIC NERVOUS SYSTEM DYSFUNCTION	Altered Intercellular Communication	Autonomic nervous system dysfunction and inflammation contribute to the increased cardiovascular mortality risk associated with depression.	20639389
Inflammation, Depression, CTCAE, Cardiovascular Diseases	Altered Intercellular Communication	To investigate prospectively whether autonomic nervous system (ANS) dysfunction and inflammation play a role in the increased cardiovascular disease (CVD)-related mortality risk associated with depression.	20639389
Autonomic nervous system, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Cox proportional hazards models were used to investigate the mortality risk associated with depression, ANS, and inflammation markers, adjusting for demographic and clinical covariates.	20639389
Inflammation, Depression, CTCAE, physiopathological	Altered Intercellular Communication	Depression was associated with ANS dysfunction (DFA(1), p = .018), and increased inflammation markers (white blood cell count, p = .012, fibrinogen p = .043) adjusting for covariates.	20639389
Inflammation, Depression, CTCAE, Autonomic nervous system disorders	Altered Intercellular Communication	Autonomic dysfunction and inflammation contribute to the increased cardiovascular mortality risk associated with depression, but a large portion of the predictive value of depression remains unexplained by these neuroimmunological measures.	20639389
Chronic lymphocytic inflammation, Pontine structure, Clippers	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS).	20639547
Encephalomyelitis, Pontine structure, Clippers, Chronic lymphocytic inflammation	Altered Intercellular Communication	In this article we report eight patients with a clinically and radiologically distinct pontine-predominant encephalomyelitis we have named 'chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids' (CLIPPERS).	20639547
Chronic lymphocytic inflammation, Pontine structure	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids is a definable, chronic inflammatory central nervous system disorder amenable to immunosuppressive treatment.	20639547
Abnormal renal function, Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD) is characterized by progressive kidney dysfunction accompanied by accumulation of uremic toxins and a potential disequilibrium between the redox status and the generation of prooxidants, resulting in oxidative stress and chronic inflammation which is associated with complications (particularly cardiovascular disease) in this population.	20639676
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	These findings indicate the importance of renal function in the complications of CKD related to oxidative stress and inflammation.	20639676
Degenerative polyarthritis, Pain Distress Question, Morning stiffness - joint, Erythema	Altered Intercellular Communication	Etodolac-paracetamol was significantly superior to etodolac alone in reducing pain intensity (P<0.001), achieving pain relief (P<0.05) during the first 4 hours after the study dose administration, and resolution of the clinical signs and symptoms of OA flare-up such as morning stiffness, swelling/inflammation, and erythema.	20639739
Inflammation, Cytokeratin, Exacerbation of cGVHD	Altered Intercellular Communication	Post operative inflammation were evaluated by slit lamp examination of cells, flares & keratic precipitate (KP).	20639824
Inflammation, Inflammatory dermatosis, Pustulosis of Palms and Soles	Altered Intercellular Communication	Earlier findings indicate the acrosyringium as the target for the inflammation in the chronic and intensely inflammatory skin disease palmoplantar pustulosis (PPP).	20640434
Inflammation, Malnutrition, Cardiovascular Diseases	Altered Intercellular Communication	In a pre-dialysis population, female gender, cardiovascular disease, malnutrition and inflammation are associated with a higher ESA/Hb index.	20640598
Inflammation	Altered Intercellular Communication	Red ginseng extract increased CD34(+) , CXCR4(+) and CD117(+) circulating angiogenic cell mobilization and decreased inflammation in AMI patients, thereby improving CFR during the 8-month follow-up.	20641058
Failure (biologic function)	Altered Intercellular Communication	Focused parathyroidectomy guided by intraoperative parathyroid hormone monitoring (IPM) may lead to higher failure rates because of missed multiglandular disease.	20644124
vascular inflammations, Endothelial dysfunction	Altered Intercellular Communication	Resveratrol (RV)-induced SirT1 activation also improves endothelial dysfunction and suppresses vascular inflammation.	20644332
Inflammation, Perforation (observation)	Altered Intercellular Communication	Diagnostic value of inflammation markers in predicting perforation in acute sigmoid diverticulitis.	20645093
Inflammation, Perforation (observation)	Altered Intercellular Communication	The importance of inflammation markers in predicting perforation in acute sigmoid diverticulitis is not well known.	20645093
Chronic kidney disease stage 5, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Apelin: a potential link between inflammation and cardiovascular disease in end stage renal disease patients.	20645679
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	T helper type 17 (Th17) and regulatory T cells (T(reg) ) play an important role in the pathogenesis of inflammation and autoimmune disorders.	20646003
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	These findings suggest that the CXCL12/CXCR4 axis contributes to inflammation in UIP and f-NSIP by promoting the accumulation CXCR4(+) lymphocytes, and a decrease of Treg is correlated with the severity of fibrosis in UIP.	20646340
Pneumonitis	Altered Intercellular Communication	And it has a close correlation with CD4+ and CD8+ lymphocytes in lung, lung parenchyma destruction, pulmonary inflammation, pulmonary artery reconstruction and airflow limitation.	20646637
Inflammation, Edema	Altered Intercellular Communication	Magnetic resonance imaging revealed a cervical epidural abscess, and accompanying edema or inflammation of the right side of the spinal cord at the C5 level.	20647654
Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	We report a 23-year-old woman with interstitial inflammation and fibrosis associated with deposition of surfactant proteins in the airways.	20647661
Airway structure, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Biopsy of the lung showed multiple focal lesions containing dilated airways with inflammation and fibrosis.	20647661
Interstitial infiltrates, Interstitial inflammation	Altered Intercellular Communication	The higher LVD was significantly associated with interstitial inflammation, and the newly formed lymph vessels were accompanied by diffuse and nodular interstitial infiltrates composed mainly of CD20(+) B cells and CD27(+) plasma cells.	20648479
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation and oxidant/antioxidant imbalance.	20648694
Inflammation	Altered Intercellular Communication	Moreover, a close correlation was found between the condition of bowel inflammation and that of mucocutaneous lesions.	20649713
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	In OA bone, expression of critical regulators of osteoblast differentiation (TWIST1) and function (PTEN, TIMP4) were decreased, while genes associated with inflammation (SMAD3, CD14) were increased.	20650323
Adenocarcinoma of lung (disorder)	Altered Intercellular Communication	Recent evidence suggests that the hormonal status may contribute to the pathogenesis of lung adenocarcinoma.	20650541
Inflammation, Atherosclerosis	Altered Intercellular Communication	The immune response mediated by the antigen-specific T cells, especially that mediated by type 1 T helper cells secreting IFN-gamma, may play an important role in the instability of plaques, and CRP may promote the inflammation of atherosclerosis through the effects on the specific immune response to oxLDL.	20650780
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterised by neutrophilic inflammation in the airways and these neutrophils contribute to the production of inflammatory mediators.	20650986
Inflammation	Altered Intercellular Communication	In conclusion, dexamethasone induces a pro-inflammatory shift in the IL-1b:sIL-1Ra cytokine balance in neutrophils in vitro, which might contribute to a lack of endogenous anti-inflammatory signals to dampen inflammation in vivo.	20650986
Inflammation	Altered Intercellular Communication	In conclusion, dexamethasone induces a pro-inflammatory shift in the IL-1b:sIL-1Ra cytokine balance in neutrophils in vitro, which might contribute to a lack of endogenous anti-inflammatory signals to dampen inflammation in vivo.	20650986
Adenocarcinoma, Inflammation, Thickening of pleura, Lymphoma	Altered Intercellular Communication	The other five patients had pleural thickening (two patients), metastatic adenocarcinoma (one patient), chronic inflammation (one patient), and malignant lymphoma (one patient).	20651171
Hepatitis, Fibrosis Assessment, Fatty degeneration, Hepatitis C, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	When surrogate markers of liver inflammation (alanine aminotransferase, aspartate aminotransferase/alanine aminotransferase ratio and alpha-fetoprotein) were removed from the model, type 2 diabetes mellitus (P=0.001), steatosis (P=0.03) and duration of HCV infection by 10-year intervals (P=0.02) were associated with advanced fibrosis.	20652161
Inflammation, Mycoses, Ear Inflammation	Altered Intercellular Communication	We have found it satisfactory in treating otitis media and other intractable inflammation and fungal infection of the external auditory canal.	20653194
Communicable Diseases, Inflammation, Cholesteatoma	Altered Intercellular Communication	Although this usually cannot completely cure middle-ear and attic cholesteatoma, its effectiveness in cases of EACC and MCC should be recognized in infection and inflammation with cholesteatoma.	20653194
Inflammation	Altered Intercellular Communication	Additional findings such as flow velocity, inflammation, and disruption of the epidermal architecture could be documented.	20653723
Mastitis, Fibrosis Assessment	Altered Intercellular Communication	The three types of mastitis presented similar ultrasound findings and shared certain histological features including fibrosis and diffuse or lobulocentric inflammation.	20653779
Inflammation, Cardiovascular system	Altered Intercellular Communication	This study investigated whether inflammation could be part of the mechanism leading to temperature-related cardiovascular deaths.	20653951
Inflammation	Altered Intercellular Communication	Cumulative exposure to decreased temperature is associated with an increase in inflammation marker levels among elderly men.	20653951
Inflammation, Cardiovascular system	Altered Intercellular Communication	This suggests that inflammation markers are part of intermediate processes, which may lead to cold-, but not heat-, related cardiovascular deaths.	20653951
Inflammation, Dyslipidemias, Atherosclerosis	Altered Intercellular Communication	Patients undergoing continuous ambulatory peritoneal dialysis (CAPD) often have inflammation and dyslipidemia that accelerate to atherosclerosis.	20654604
Granulomatous inflammation, Infiltration	Altered Intercellular Communication	Biopsy of his right superficial temporal artery revealed a granulomatous inflammation with multinucleated giant cell infiltration.	20654795
Inflammation, Dyssomnias, Fatigue	Altered Intercellular Communication	Individuals with underlying inflammation present with a high prevalence of non-specific co-morbid symptoms including sleep disturbance and fatigue.	20656013
Inflammation	Altered Intercellular Communication	Relative loss of slow wave sleep may be one pathway through which cellular inflammation leads to daytime fatigue.	20656013
Prostate carcinoma, prostatitis	Altered Intercellular Communication	[Predictive value of the asymptomatic prostatic inflammation in the development of prostate cancer].	20656273
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Several studies have tried to show a link between inflammation and cancer.	20656273
Inflammation, Atrophic	Altered Intercellular Communication	Inflammation and several histological criterions were evaluated: acute/chronic and focal/diffuse inflammation, atrophy, high grade PIN (HGPIN) and ASAP.	20656273
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	According to these data, the presence and type of histological inflammation on initial prostate biopsies did not seem to be a risk factor for the development of PCa.	20656273
Inflammation, Foveolar-Type Adenoma, Duodenitis	Altered Intercellular Communication	Of 28,210 patients with duodenal biopsy specimens, 80.9% were healthy, 2.1% had active duodenitis, 2.2% gastric foveolar metaplasia without active inflammation ("peptic duodenopathy"), 4.8% gastric foveolar metaplasia with active inflammation ("peptic duodenitis"), and 1.9% gastric heterotopia.	20656325
Inflammation, Gastric metaplasia, Helicobacter-associated gastritis, Foveolar-Type Adenoma, Duodenitis	Altered Intercellular Communication	Helicobacter pylori was documented in 9.8% of patients with normal duodenum, 6.9% of those with gastric metaplasia without active inflammation, 15.8% of those with active duodenitis, and 29.1% of those with gastric foveolar metaplasia with active inflammation; 2.2% of 543 patients with gastric heterotopia had H pylori gastritis.	20656325
Inflammation, Metaplasia	Altered Intercellular Communication	Helicobacter pylori was detected in the metaplastic epithelium of 67.6% of patients with active inflammation and in 16.4% of those with metaplasia without inflammation.	20656325
Inflammation, Fibrous	Altered Intercellular Communication	Polyethylene wear particles do not induce inflammation or gelatinase (MMP-2 and MMP-9) activity in fibrous tissue interfaces of loosening total hip arthroplasties.	20656340
Inflammation, Genes, Wilms Tumor	Altered Intercellular Communication	Long-term administration of Wilms tumor-1 peptide vaccine in combination with gemcitabine causes severe local skin inflammation at injection sites.	20656693
Inflammation, Liver Cirrhosis, Fatty Liver Disease	Altered Intercellular Communication	NADPH, a marker of inflammation and fibrinogenic activity in the liver, is increased in patients with NASH and those with cirrhosis.	20656836
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Role of breast regression protein-39 in the pathogenesis of cigarette smoke-induced inflammation and emphysema.	20656949
Inflammation	Altered Intercellular Communication	These studies demonstrate a novel regulatory role of BRP-39/YKL-40 in CS-induced inflammation and emphysematous destruction.	20656949
Inflammatory abnormality of the eye, Atopic keratoconjunctivitis	Altered Intercellular Communication	Case report of restoration of the corneal epithelium in a patient with atopic keratoconjunctivitis resulting in amelioration of ocular allergic inflammation.	20657166
Keratoconjunctivitis, Vernal, Conjunctivitis, Atopy	Altered Intercellular Communication	Atopic and vernal keratoconjunctivitis are severe types of ocular allergic disease characterized not only by conjunctival inflammation but also by corneal involvement.	20657166
Inflammatory abnormality of the eye	Altered Intercellular Communication	In vitro studies have suggested that breakdown of corneal epithelial barrier function and subsequent activation of stromal fibroblasts may amplify ocular allergic inflammation.	20657166
Corneal endothelial plaque, Conjunctivitis	Altered Intercellular Communication	Surgical removal of corneal plaque and administration of autologous fibronectin eyedrops resulted not only in resurfacing of the corneal epithelium but also in amelioration of conjunctival inflammation.	20657166
Conjunctivitis	Altered Intercellular Communication	This case suggests that loss of corneal epithelial integrity likely exacerbates conjunctival allergic inflammation and that restoration or maintenance of the barrier function of the corneal epithelium may be one of the important targets for the treatment of severe ocular allergic diseases.	20657166
Inflammation, Obesity	Altered Intercellular Communication	The relationships among stress, obesity, and inflammation in women remain unclear.	20658213
Communicable Diseases, Inflammation	Altered Intercellular Communication	Postoperative systemic inflammation response syndrome(SIRS) and infection were evaluated.	20658369
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Substance P is associated with the development of obesity, chronic inflammation and type 2 diabetes mellitus.	20658441
Obesity	Altered Intercellular Communication	Substance P (SP) is an important neurotransmitter and is an important pathogenic factor in obesity.	20658441
Inflammation	Altered Intercellular Communication	Assessment of anterior chamber inflammation after intravitreal bevacizumab injection in different ocular exudative diseases.	20658459
Inflammation	Altered Intercellular Communication	To investigate the inflammation of the anterior chamber after intravitreal bevacizumab injection in different ocular exudative diseases.	20658459
Nonproliferative diabetic retinopathy, Inflammation, Choroidal Neovascularization, Edema	Altered Intercellular Communication	The extent of inflammation in the anterior chamber did not change after intravitreal bevacizumab injection in patients with nonproliferative diabetic retinopathy, choroidal neovascularization secondary to age-related macular degeneration, or macular edema due to branch or central vein occlusion.	20658459
Inflammation, Bronchial Obstruction, Bronchiectasis, Aspergillosis, Allergic Bronchopulmonary, Fibrosis Assessment, Mucus retention, Respiratory Failure	Altered Intercellular Communication	Recurrent episodes of bronchial obstruction, inflammation, and mucoid impaction occur in ABPA and results in bronchiectasis, fibrosis, and respiratory failure.	20658484
Aspergillosis, Allergic Bronchopulmonary, Inflammation, Fungal Colonization, Lung Injury	Altered Intercellular Communication	The treatment of ABPA includes corticosteroids to reduce the acute inflammation and intraconazole to reduce the fungal colonization load in order to reduce lung injury.	20658484
Inflammation, activation of blood coagulation via clotting cascade	Altered Intercellular Communication	The relationship between inflammation, obesity-related proteins and tissue factor (TF), the major initiator of the extrinsic clotting cascade, is not well understood.	20659134
Inflammation	Altered Intercellular Communication	Within 24 h after admission, moderate elevation of TC level seemed to increase the resistance to inflammation and hence improved the survival rate in patients with SAP, and reduced the in-hospital mortality.	20659228
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Impaired lung function	Altered Intercellular Communication	Inadequate glucose control in type 2 diabetes is associated with impaired lung function and systemic inflammation: a cross-sectional study.	20659337
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Inadequate glucose control may be simultaneously associated with inflammation and decreased lung function in type 2 diabetes.	20659337
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Invited commentary: human cytomegalovirus, inflammation, cardiovascular disease, and mortality.	20660119
Inflammation, Autoimmune Chronic Hepatitis	Altered Intercellular Communication	Our data suggest that elevated serum F-actin antibody titers are commonly encountered in HCV-infected patients and may reflect more active inflammation in liver biopsy samples, similar to autoimmune hepatitis.	20660325
methyldopa, Inflammation	Altered Intercellular Communication	We propose that the impaired binding of the 402H variant to Bruch's membrane results in an overactivation of the complement pathway leading to local chronic inflammation and thus contributes directly to the development and/or progression of AMD.	20660596
Inflammation, Atherosclerosis, Giant Cell Arteritis, GCA gene, Cerebrovascular accident	Altered Intercellular Communication	It is not established whether the increased risk of stroke in patients with giant cell arteritis (GCA) is because of atherosclerosis, persistent arterial inflammation, or an iatrogenic effect of corticosteroids.	20661069
Inflammation, Compassion Fatigue	Altered Intercellular Communication	More than 2 mitotic figures per lesion can usually be explained either by the nevus subtype, young patient age, traumatization, or inflammation.	20661119
Asbestos-Related Lung Disorder, Pleurisy, 1-methyl-1-piperidinomethane sulfonate	Altered Intercellular Communication	PET/CT might be more helpful than plasma osteopontin for distinguishing benign asbestos-related pleural diseases from MPM, and the SUVmax in benign asbestos-related pleural diseases may reflect changes in pleural inflammation.	20661695
Hepatitis B, Impaired T cell function, Hepatitis	Altered Intercellular Communication	Intrahepatic levels of PD-1/PD-L correlate with liver inflammation in chronic hepatitis B. Programmed cell death-1 (PD-1) represents a mechanism of T-cell dysfunction in hepatitis B virus (HBV) persistence.	20661763
Inflammation, Complete atrioventricular block	Altered Intercellular Communication	Within the CHB patients, the increases in labeling indexes of PD-1 and PD-L paralleled the degree of inflammation.	20661763
Chronicity, Inflammation, Complete atrioventricular block, Immune System Diseases	Altered Intercellular Communication	These results suggest that over-expression of PD-1, PD-L1 and PD-L2 within liver may participate in local immune dysfunction, which could be one of the mechanisms involved in the chronicity of HBV infection and chronic inflammation seen in CHB patients.	20661763
Inflammation, Papilledema	Altered Intercellular Communication	Despite topical steroids and mydriatics, inflammation worsened and bilateral optic nerve swelling developed.	20662661
Inflammatory abnormality of the eye	Altered Intercellular Communication	Oral corticosteroids settled the ocular inflammation, and optic nerve function recovered.	20662661
Malignant neoplasm of urinary bladder, Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammations following BCG therapy for bladder cancer are rare, and little is known about the management of such cases.	20662661
Inflammation, Atherosclerosis, diabetic, Endothelial dysfunction, Hypertension, CTCAE	Altered Intercellular Communication	Endothelial dysfunction is a common feature in type-2 diabetic patients and in hypertension, and is associated with inflammation, increased levels of circulating soluble adhesion molecules, and atherosclerosis.	20662732
Endothelial dysfunction	Altered Intercellular Communication	Malnutrition-inflammation score and endothelial dysfunction in hemodialysis patients.	20663689
Inflammation, Hyperparathyroidism, Diabetes Mellitus	Altered Intercellular Communication	In patients with diabetes, inflammation or severe hyperparathyroidism, the REE estimated by the Harris and Benedict equation was equivalent to that measured by indirect calorimetry.	20663791
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Association between systemic inflammation and incident diabetes in HIV-infected patients after initiation of antiretroviral therapy.	20664016
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	To determine whether systemic inflammation after initiation of HIV-antiretroviral therapy (ART) is associated with the development of diabetes.	20664016
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	These findings suggest that systemic inflammation may contribute to diabetes pathogenesis among HIV-infected patients.	20664016
Inflammation, Hemorrhage, Necrosis	Altered Intercellular Communication	We semi-quantitatively analysed intensity of inflammation, necrosis, haemorrhage and lipid depletion.	20665002
Inflammation, Hemorrhage, Septic Shock, Necrosis	Altered Intercellular Communication	In adrenal cortex, in patients and not in animals, global scores for inflammation (p = 0.002), necrosis (p = 0.009) and haemorrhage (p = 0.009) were significantly higher in septic shock than in controls.	20665002
Inflammation, Hemorrhage, Septic Shock, Necrosis	Altered Intercellular Communication	Similarly, in zona fasciculata, in patients and not in animals, scores for inflammation (p = 0.007), necrosis (p = 0.023) and haemorrhage (p = 0.023) were significantly higher in septic shock than in controls.	20665002
Sepsis, Inflammation, Hemorrhage, Necrosis	Altered Intercellular Communication	In patients, sepsis was associated with inflammation, necrosis and haemorrhage predominantly in zona fasciculata.	20665002
ARCN1 gene, Inflammation	Altered Intercellular Communication	At present, COPD is known to be a systemic disease resulting from generalized inflammation which affects the function of many organs.	20665447
Inflammation	Altered Intercellular Communication	Generalized inflammation is recognized from increased serum concentration of inflammatory cytokines.	20665447
Inflammation	Altered Intercellular Communication	Exclusion criteria included coexistence of other diseases and/or medication causing an increase of markers of inflammation.	20665447
Inflammation, Atrophic, Skeletal muscle weakness	Altered Intercellular Communication	MCK-bAPP mice show an age-dependent increase in [Ca(2+)](i) along with a reduction in depolarization-evoked Ca(2+) release, which appear well before the other reported aspects of IBM, such as inclusion formation, inflammation, centralized nuclei, atrophy, and skeletal muscle weakness.	20665519
Carcinoma, Primary infertility	Altered Intercellular Communication	Primary and bilateral tubal carcinoma is associated with long-standing granulomatous inflammation and primary infertility: a case report.	20666969
Granulomatous inflammation, Non-Metastatic Carcinoma, Primary infertility	Altered Intercellular Communication	We report a case of bilateral and primary tubal carcinoma associated with granulomatous inflammation and long-standing primary infertility.	20666969
Granulomatous inflammation, Primary infertility, Abdominal Pain	Altered Intercellular Communication	A 38-year-old woman with a 17-year history of primary infertility presented with lower abdominal pain and granulomatous inflammation in the endometrial biopsy.	20666969
Pelvic Inflammatory Disease	Altered Intercellular Communication	A definitive diagnosis could be made on the histopathological examination in our case with the evidence of chronic pelvic inflammation.	20666969
Carcinogenesis, Pelvic Inflammatory Disease	Altered Intercellular Communication	Our findings suggest that chronic pelvic inflammation may play a role in carcinogenesis in the tubes of infertile women.	20666969
Fibrinoid necrotizing inflammation	Altered Intercellular Communication	Interestingly, the cause of autograft failure was not related to the rheumatoid inflammation process.	20667306
Inflammation, Injury of gastrointestinal tract	Altered Intercellular Communication	Plasma citrulline concentration, as a sign of intestinal injury, and C-reactive protein, orosomucoid, albumin, a(1)-antitrypsin, and haptoglobin, as signs of systemic inflammation, were analyzed.	20667967
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation is fundamental to the cause and persistence of asthma and other airway conditions.	20668016
Airway structure	Altered Intercellular Communication	However, the presence and type of airway inflammation can be difficult to detect clinically, delaying the introduction of appropriate treatment.	20668016
Airway structure	Altered Intercellular Communication	They can accurately discriminate eosinophilic airway inflammation from noneosinophilic airway inflammation and, thus, help to guide therapy.	20668016
Airway structure, Inflammation	Altered Intercellular Communication	Eosinophilic airway inflammation is steroid responsive, whereas noneosinophilic (usually neutrophilic) inflammation generally is not.	20668016
ARCN1 gene, airway disease, Chronic cough, Airway structure, Asthma	Altered Intercellular Communication	Monitoring of airway inflammation using sputum cell counts helps to identify the impending loss of asthma control and, thus, the need to adjust antiinflammatory medications in patients with a variety of airway diseases, such as asthma, smoker's COPD, and chronic cough.	20668016
Airway structure	Altered Intercellular Communication	Other noninvasive, indirect measurements of airway inflammation, such as exhaled nitric oxide, do not help to identify the cellular nature of airway inflammation associated with exacerbations of airway diseases, particularly in patients who are already on corticosteroids.	20668016
vascular inflammations	Altered Intercellular Communication	Moreover, a remarkable association of the G82S variant with serum CRP levels implied that the prevalence of RAGE 82S allelic variation might influence susceptibility to CAD by affecting vascular inflammation.	20668462
Intestinal metaplasia, Gland, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Intestinal metaplasia (IM), glandular atrophy and mucosal inflammation were diagnosed from histological specimens and graded according to the updated Sydney-classification.	20668939
Inflammation	Altered Intercellular Communication	In contrast, there was more severe active inflammation in the corpus than the antrum (P = 0.017).	20668939
Inflammation, Neoplasms	Altered Intercellular Communication	Incomplete colonoscopies due to stenosis (78.9 %), severe inflammation (77.8 %) or an obstructing tumor (74.6 %) were most frequently followed by a secondary examination.	20669092
Aspergillosis	Altered Intercellular Communication	Invasive sino-orbital-skull base aspergillosis often may resemble inflammatory conditions.	20669647
Inflammation, Hypertension, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	[Effects of tongxinluo capsule on platelet activating and inflammation factors as well as vascular endothelial function in patients with essential hypertension complicated with diabetes mellitus].	20669673
vascular inflammations, Demographics Domain	Altered Intercellular Communication	TXLC can inhibit the platelet activation and vascular inflammation response, also improve the vascular endothelial function in patients with EH complicated with DM.	20669673
Airway structure	Altered Intercellular Communication	Fractional exhaled nitric oxide (FeNO) measurement is a reliable, noninvasive marker of airway inflammation.	20670207
Airway structure	Altered Intercellular Communication	The use of portable FeNO analyzers may enable the assessment of airway inflammation in primary care.	20670207
Heart Failure, Systolic	Altered Intercellular Communication	Clinical significance of endogenous vasoactive neurohormones in chronic systolic heart failure.	20670842
Inflammation, Complication Aspects	Altered Intercellular Communication	Moreover, resistin may induce thrombotic complications via mediating the lipoprotein metabolism and stimulating inflammation.	20671416
Pain Distress Question, Erythema, Inflammation	Altered Intercellular Communication	After this infusion, the patient complained of pain around the site of injection and presented a 10x6-cm swollen area with erythema and inflammation.	20671512
Cataract, Inflammation, Hemorrhage	Altered Intercellular Communication	Prompt cataract removal led to resolution of the inflammation, clearing of the anterior chamber haemorrhage, and normalization of intraocular pressure in all four affected eyes.	20671768
Ocular Hypertension, Uveitis, Traumatic injury, Hyphema, Pathologic Neovascularization	Altered Intercellular Communication	spontaneous hyphaema and acute ocular hypertension can occur in patients with severe lens-induced intraocular inflammation in the absence of trauma or ocular neovascularization.	20671768
Inflammation	Altered Intercellular Communication	These results strongly suggest that PPARgamma plays a key role in age-related inflammation and may have clinical applications as a molecular target in the treatment of age-related inflammation.	20672248
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) itself causes hormonal changes.	20673032
Intraocular inflammation	Altered Intercellular Communication	This report describes the occurrence of intraocular inflammation after treatment with the TNF-alpha antagonist etanercept.	20673052
Inflammation, Primary malignant neoplasm, Neoplasms, Carcinoma of lung, Lip and Oral Cavity Carcinoma	Altered Intercellular Communication	Recent advances in understanding complex tumor interactions have led to the discovery of an association between inflammation and cancer, in particular for colon and lung cancer, but only a very few have dealt with oral cancer.	20673375
Inflammation, Keratitis	Altered Intercellular Communication	Diffuse lamellar keratitis (DLK) is a sterile inflammation after laser in situ keratomileusis.	20674084
Inflammation	Altered Intercellular Communication	Matrix metalloproteinase (MMP)-9 is involved in both inflammation and matrix degradation and considered a main contributor to coronary plaque rupture.	20674181
Inflammation, Tumor necrosis, Vascular calcification	Altered Intercellular Communication	Many studies have provided evidence for a role of inflammation and inflammatory cytokines such as tumour necrosis factor (TNF)-a and interleukin (IL)-1b in the vascular calcification process.	20674184
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	We conclude that elevated serum DcR3 may serve as an indicator of active colonic inflammation in patients with UC.	20675196
Inflammation, Viral keratitis, Corneal Diseases	Altered Intercellular Communication	The signs of inflammation in corneal layers were detected especially in group of patients classified as viral keratitis but were also found in corneas of patients with degenerative diseases of the cornea.	20675284
Inflammation	Altered Intercellular Communication	The CT scan showed a thickened gallbladder with adjacent inflammation and a 2-cm pseudo-aneurysm in its wall.	20675459
Orbital Pseudotumor	Altered Intercellular Communication	To identify risk factors involved in the development of idiopathic orbital inflammation (IOI).	20675725
Intraocular inflammation	Altered Intercellular Communication	In addition, none of the samples from the control patients without intraocular inflammation were positive.	20675730
Inflammation, Anastomotic Leak	Altered Intercellular Communication	Anastomotic leakage was associated with patient co-morbidity rather than with intraoperative Hinchey category, suggesting that the decision to perform PA should better be based on patient's general condition rather than on intraoperative extent of inflammation.	20676663
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Chronic inflammation has been consistently associated with cancers of several sites, including the breast, and inhibition of inflammation through the use of non-steroidal anti-inflammatory drugs (NSAIDs) has been inversely associated with risk.	20676755
Autoimmune Diseases, Optic Neuritis	Altered Intercellular Communication	A 41-year-old man presented with left optic neuritis (ON) without evidence of other autoimmune disease or hormonal imbalance.	20676777
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	3'-Nitrotyrosine (3NT) is a post-translational modification (PTM) of body fluids and tissues that is sustained by chronic inflammation and oxidative stress, two main clinical traits of chronic kidney disease (CKD).	20676907
Inflammation, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Chronic hepatitis had been proved by liver biopsy in the majority of cases and/or biological markers of inflammation and fibrosis.	20677341
Tolosa-Hunt Syndrome, Inflammation, Orbital fissure	Altered Intercellular Communication	Tolosa-Hunt syndrome is a nonspecific granulomatous inflammation of the cavernous sinus, superior orbital fissure and apex of the orbit.	20677620
Airway structure	Altered Intercellular Communication	However, in the majority of these subjects airway inflammation is still present when measured.	20678209
Airway structure	Altered Intercellular Communication	Sputum induction and AMP provocation were previously shown to be sensitive markers of airway inflammation.	20678209
Inflammation, Asthma	Altered Intercellular Communication	Subjects with complete asthma remission, in contrast to subjects with current asthma, do not respond with eosinophilic inflammation in sputum after AMP provocations.	20678209
Inflammation, Malignant neoplasm of gallbladder, Carcinoma, Hyperplasia and Metaplasia	Altered Intercellular Communication	The development of gallbladder cancer occurs over a long time (more than 15 y) and evolves from chronic inflammation to dysplasia/metaplasia, carcinoma in situ, and invasive carcinoma.	20679224
Inflammation	Altered Intercellular Communication	Immunoglobulin (Ig) free light chains (FLCs) are short-lived B cell products that contribute to inflammation in several experimental disease models.	20679475
Sleep-Disordered Breathing, Inflammation	Altered Intercellular Communication	Sleep-disordered breathing (SDB) is thought to be a state of inflammation caused by hypoxic stress.	20679736
Vasculitis, Pulmonary Hypertension	Altered Intercellular Communication	Increased platelet, leukocyte and endothelial microparticles predict enhanced coagulation and vascular inflammation in pulmonary hypertension.	20680403
vascular inflammations, Endothelial dysfunction, Pulmonary Hypertension	Altered Intercellular Communication	Pulmonary hypertension (PH) is associated with platelet activation, vascular inflammation and endothelial dysfunction leading to often life threatening thrombo-embolic complications.	20680403
Inflammation, Hyperplastic Polyp	Altered Intercellular Communication	PH patients have increased levels of platelet-, leukocyte- and endothelial MP indicating an increased vascular pro-coagulation and inflammation which might be related to thrombo-embolic complications as well as PH progression.	20680403
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Biomarkers of inflammation, endothelial dysfunction and insulin resistance in adults of Inner Mongolia, China.	20680929
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Low-grade chronic inflammation and endothelial dysfunction have been hypothesized to underlie the constellation of cardiometabolic risk factors, possibly by inducing insulin resistance.	20680929
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	This study suggests that inflammation and endothelial dysfunction may relate to insulin resistance.	20680929
Communicable Diseases, Visual Impairment, Inflammation, Infection	Altered Intercellular Communication	Risk factors for visual impairments following bleb-related infections were recurrence of infection (p = 0.022), negative Seidel tests (p = 0.0056), aphakia (p = 0.045), avitreous (p = 0.00070), positive Streptococcus species (p = 0.029), and prolonged inflammation (p = 0.014).	20681255
Inflammation	Altered Intercellular Communication	The finding that the patient recovered after corticosteroid therapy alone suggests that non-infectious inflammation played a major role in the pathogenesis.	20681268
Inflammation, Idiopathic hypertrophic pachymeningitis, Cholesteatoma, Ear Inflammation	Altered Intercellular Communication	Chronic inflammation associated with otitis media with cholesteatoma or surgical invasiveness might induce the recurrence of idiopathic hypertrophic pachymeningitis.	20681268
Inflammation, Periodontal Diseases	Altered Intercellular Communication	Interleukin (IL)-6, a multifunctional cytokine, plays a role in the tissue inflammation that characterizes periodontal disease.	20682019
Inflammation, Albuminuria	Altered Intercellular Communication	Inflammation, kidney function and albuminuria in the Framingham Offspring cohort.	20682604
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation and chronic kidney disease (CKD) are both associated with cardiovascular disease (CVD).	20682604
Inflammation, Albuminuria	Altered Intercellular Communication	Biomarkers of inflammation are associated with kidney function and albuminuria.	20682604
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Are lipid ratios less susceptible to change with systemic inflammation than individual lipid components in patients with rheumatoid arthritis?	20682616
Refractory anemias, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	In summary, the effects of inflammation on individual lipid levels may underestimate lipid-associated cardiovascular disease (CVD) risk in RA, thus lipid ratios may be more appropriate for CVD risk stratification in RA.	20682616
Inflammation	Altered Intercellular Communication	Interleukin 33 (IL-33) is a novel cytokine involved in joint inflammation in animal models.	20682660
Refractory anemias, Inflammation	Altered Intercellular Communication	However, no correlation was found between IL-33 concentration and acute-phase inflammation reactant or the score of the Disease Activity Index, suggesting a complex or indirect character of the link between IL-33 and the inflammation in RA.	20682660
Inflammation	Altered Intercellular Communication	C-C chemokine receptor 5 (CCR5) plays an important role in inflammation.	20682662
Gastrointestinal inflammation	Altered Intercellular Communication	However, the role of MBL in intestinal inflammation is currently unclear.	20682699
Inflammation	Altered Intercellular Communication	These results suggest that systemic MBL helps to prevent excessive inflammation upon access of normally mild pathogens across the damaged intestinal epithelium.	20682699
Communicable Diseases, Inflammation	Altered Intercellular Communication	The specificity of Tc-UBI for localizing infection foci and for discarding sterile inflammation was 95.35%, the sensitivity was 97.52%, the positive predictive value was 96.72%, the negative predictive value was 96.47%, the accuracy was 96.62%, and the observed agreement between the bacterial culture and the molecular image was 96.62% (P=0.0001).	20683364
Communicable Diseases, Inflammation	Altered Intercellular Communication	Considering that the absolute and relative frequencies are very high, we propose that, in the future, Tc-UBI molecular imaging could be the gold standard to detect infection sites and to discard sterile inflammation.	20683364
Fever, Fever of Unknown Origin, Fever, CTCAE, Bacterial Infections	Altered Intercellular Communication	Fever of unknown origin (FUO) represents a challenge to clinical medicine, and bacterial cultures have been considered the 'gold standard' in discriminating between fevers resulting from bacterial infection and sterile inflammations.	20683364
Inflammation, Sarcopenia, Malnutrition, Chronic disease	Altered Intercellular Communication	The causes of sarcopenia are multi-factorial and can include disuse, changing hormonal function, chronic diseases, inflammation, insulin resistance, and nutritional deficiencies.	20683658
Inflammation, Sarcopenia, Malnutrition, Chronic disease	Altered Intercellular Communication	The causes of sarcopenia are multi-factorial and can include disuse, changing hormonal function, chronic diseases, inflammation, insulin resistance, and nutritional deficiencies.	20683658
Inflammation	Altered Intercellular Communication	Only lobular inflammation improved significantly (P for the modified Brunt score = 0.011, P for NAS = 0.005).	20683947
Inflammation, Hypertension, CTCAE, Overweight	Altered Intercellular Communication	In subgroup analyses, significant improvements in lobular inflammation were also observed in males, younger patients up to 50 years of age, slightly overweight patients, and patients with hypertension and an increased histology score.	20683947
Inflammation, Fibrosis Assessment, Fatty degeneration, Diabetes Mellitus, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	After adjustment for age, sex, diabetes, and alcohol consumption, the minor allele of rs738409 C/G, a nonsynonymous coding SNP in the patatin-like phospholipase domain-containing protein 3 (PNPLA3) (adiponutrin) gene encoding an Ile148Met change, was associated with steatosis (P = 0.03), portal inflammation (P = 2.5 x 10(-4)), lobular inflammation (P = 0.005), Mallory-Denk bodies (P = 0.015), NAFLD activity score (NAS, P = 0.004), and fibrosis (P = 7.7 x 10(-6)).	20684021
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Vasculitis may cause inflammation in any single or group of blood vessels.	20685065
Autoimmune Diseases, vascular inflammations	Altered Intercellular Communication	Serum levels of adhesion molecules ICAM-1 and VCAM-1 and tissue inhibitor of metalloproteinases, TIMP-1, are elevated in patients with autoimmune thyroid disorders: relevance to vascular inflammation.	20685094
Autoimmune Diseases, Inflammation, Atherosclerosis	Altered Intercellular Communication	The physiopathological link between inflammation, atherosclerosis and autoimmunity is well demonstrated.	20685094
Inflammation	Altered Intercellular Communication	Inflammation contributes to axon reflex vasodilatation evoked by iontophoresis of an a-1 adrenoceptor agonist.	20685182
Lupus Erythematosus	Altered Intercellular Communication	We propose that development of systemic lupus erythematosus in this case may have been due to low grade chronic inflammation.	20685593
Inflammation, Carcinoma, Squamous intraepithelial lesion, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	The amplification of hTERC showed 6.06% in normal or inflammation cases, 10.00% in CIN 1, 66.67% in CIN 2, 72.50% in CIN 3, and 100.00% in carcinoma, with significant difference between the low- (or=CIN 2 or >or=atypical squamous cells in which high-grade squamous intraepithelial lesion cannot be excluded) cervical lesions (P < 0.001).	20686384
Inflammation, Ischemic stroke, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP) is one of the acute-phase proteins produced predominantly by hepatocytes in response to inflammation, and it has been widely reported that CRP genetic polymorphism is a risk factor for cardiovascular disease and ischemic stroke.	20686879
Esophagitis	Altered Intercellular Communication	The endoscopic recognition of linear furrows, concentric rings, and white exudates is important in the diagnosis of eosinophilic esophageal inflammation.	20686904
Inflammation, Acute peritonitis	Altered Intercellular Communication	These values were compared in group of 52 patients with acute peritonitis against group of 39 patients without inflammation within peritoneal cavity.	20687377
Inflammation, Iron deficiency anemia	Altered Intercellular Communication	Acute intraabdominal inflammation induced in all patients a state of hypoferremia.	20687377
Necrotizing granulomatous inflammation, Neoplasms, Pneumonia	Altered Intercellular Communication	The most common specific diagnoses were necrotizing granulomatous inflammation (45), scar (28), organizing pneumonia (13), and benign neoplasms (11).	20688352
Inflammation, Interstitial Fibrosis Assessment	Altered Intercellular Communication	A mixture of interstitial fibrosis and chronic inflammation (16) was the most common nonspecific diagnosis.	20688352
Inflammation, Fibrosis Assessment, Malignant Neoplasms	Altered Intercellular Communication	Malignancy was diagnosed on a subsequent biopsy in only one case, and the initial biopsy in that case showed non-specific chronic inflammation and fibrosis.	20688352
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Recent interest has focused on the role that inflammation may play in the development of prostate cancer and whether use of aspirin or other nonsteroidal antiinflammatory drugs (NSAIDs) affects risk.	20688905
Inflammation, Vascular System Injuries	Altered Intercellular Communication	Inhibition of p38 mitogen-activated protein kinase reduces inflammation after coronary vascular injury in humans.	20689074
Inflammation, Cerebrovascular Trauma, Myocardial	Altered Intercellular Communication	Coronary artery stents provide benefit by maintaining lumen patency but may incur vascular trauma and inflammation, leading to myocardial damage.	20689074
Inflammation, Atrial thrombosis	Altered Intercellular Communication	Although systemic inflammation is a known predictor of left atrial thrombus formation in patients with nonrheumatic AF, the relation between the CHADS2 score and systemic inflammation is unknown.	20691312
Inflammation, Atrial thrombosis	Altered Intercellular Communication	In conclusion, in patients with nonrheumatic AF, CHADS2 score is related to systemic inflammation, left atrial thrombus formation, and prognosis.	20691312
Inflammation, Fibrosis Assessment, Lacrimation	Altered Intercellular Communication	Increasing knowledge about this syndrome, including better imaging, has facilitated patient treatment for a stable spectrum of rotator cuff pathology (inflammation or fibrosis, partial-thickness tearing, full-thickness tearing undergoing debridement), as has the application of endoscopic surgery.	20691562
Inflammation, Diabetes Mellitus, Atherosclerosis	Altered Intercellular Communication	Diabetes is associated with low-grade inflammation, which has an important role in the development of atherosclerosis.	20691708
Inflammation, Diabetes Mellitus, Atherosclerosis	Altered Intercellular Communication	Currently, we followed diabetes patients to investigate, if the Pro7 allele is associated with the inflammation related to atherosclerosis.	20691708
Inflammation, Refractory anemias, Degenerative polyarthritis, Rheumatoid Arthritis, Tumor necrosis, Interphalangeal joint structure	Altered Intercellular Communication	To investigate the association between systemic and local inflammation and incident and progressive radiographic secondary osteoarthritis (OA) in interphalangeal joints (IPJs) over 3 years in rheumatoid arthritis (RA) patients and the effect of tumor necrosis factor alpha (TNF-a) inhibitor infliximab on secondary OA in IPJs.	20691795
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Infliximab treatment was associated with lower incident secondary OA in PIPJs [relative risk 0.5 (95% confidence interval 0.2, 1.0)], independent of decrease in inflammation.	20691795
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Infliximab treatment reduced incident secondary OA in PIPJs independent of decrease in inflammation, suggesting that anti-TNF-a therapy might be effective against secondary hand OA via other pathways than suppression of inflammation.	20691795
HD Term Type, Malnutrition, Inflammation, Atherosclerosis	Altered Intercellular Communication	Difficulty healing wounds and skin defects is a frequent problem in patients on chronic hemodialysis (HD) because of malnutrition, inflammation, and atherosclerosis (MIA) syndrome.	20692601
Malnutrition, HD Term Type, Inflammation	Altered Intercellular Communication	The apparent malnutrition and inflammation in HD patients are likely responsible for the decreased skin blood flow and the development of the difficulty to heal skin defects and wounds.	20692601
Inflammation, Prostate carcinoma	Altered Intercellular Communication	High intake of n-6 fatty acids, through their effects on inflammation and oxidative stress, may increase prostate cancer risk.	20693267
Inflammatory abnormality of the eye	Altered Intercellular Communication	The corresponding rates for all ocular inflammation were 450 and 467/100,000.	20693551
Inflammatory abnormality of the eye, Infectious Endophthalmitis, Uveitis	Altered Intercellular Communication	The majority of cases of posterior uveitis and infectious endophthalmitis were visually compromised, but few among the cases of other forms of ocular inflammation were visually impaired.	20693551
Inflammatory abnormality of the eye, Traumatic injury	Altered Intercellular Communication	The results suggest that nearly one in 200 persons in rural, South India has been affected by ocular inflammation in at least one eye by mid to late adulthood, about one in 330 if cases related to surgery or trauma are not included.	20693551
Inflammation, Hypermetabolism, Burn injury	Altered Intercellular Communication	Girls also have less inflammation and hypermetabolism after major burns.	20693914
abdominal sepsis, Inflammation	Altered Intercellular Communication	Edema and inflammation due to abdominal sepsis can prevent the use of standard management (i.e., colostomy, ileostomy or Hartmann's procedure), in which case alternative salvage repair methods are required.	20694495
Sleep-Disordered Breathing, Inflammation	Altered Intercellular Communication	SDB has a high prevalence in CAD patients and seems to be associated with chronic inflammation, which may be linked to CAD progression and/or acute coronary events.	20694765
Inflammation, Cardiovascular Diseases, Atherosclerosis	Altered Intercellular Communication	Inflammation and oxidative stress are associated with cardiovascular diseases and underlying atherosclerosis.	20695884
Refractory anemias, Inflammation, Damage	Altered Intercellular Communication	Treatment strategies for RA have improved dramatically over the last decades, resulting in less inflammation and joint damage.	20696679
Inflammation	Altered Intercellular Communication	Reduction of the PaO2/FiO2 ratio in acute aortic dissection - relationship between the extent of dissection and inflammation -.	20697178
Inflammation	Altered Intercellular Communication	The process of healing of chronic periapical inflammation lasted longer in patients aged 45-78 years than in patients aged 17-44 years.	20698178
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The resected specimens were examined histopathologically to determine the degree of inflammation and the presence of malignancy.	20698210
Inflammation, Arthritis, Gouty	Altered Intercellular Communication	To relate the expression of the matrix degrading proteinase cathepsin B and its endogenous inhibitor cystatin C in the synovial fluid (SF) to the clinical and laboratory variables of joint inflammation in gouty arthritis of the knee.	20699092
Inflammation, Gout	Altered Intercellular Communication	These results show a high correlation between the cathepsin B/cystatin C system and markers of joint inflammation in acute gout of the knee, demonstrating the pathologic role of cathepsin B and cystatin C in inflammation.	20699092
Hypoglycemia, Neuroglycopenia	Altered Intercellular Communication	This increased vulnerability may be due to more symptom "noise" (more symptoms during euglycemia), making it harder to detect hypoglycemia while driving; possibly greater carbohydrate utilization, rendering them more vulnerable to experiencing hypoglycemia; less hormonal counterregulation, leading to more profound hypoglycemia; and more neuroglycopenia, rendering them more vulnerable to impaired driving.	20699432
Inflammation, Fibrosis Assessment, Fatty degeneration, Fatty Liver Disease	Altered Intercellular Communication	The mean ALT (P = 0.012), SAP (P = 0.003), serum bilirubin (P = 0.001), AST/ALT ratio (P = 0.03), steatosis (P < 0.001), ballooning degeneration of hepatocytes (P < 0.001), portal inflammation (P < 0.001), Mallory hyaline (P = 0.001), ductular proliferation and fibrosis (P < 0.001) showed a significant difference between ASH and NASH cases.	20699492
Fibrosis Assessment, Portal inflammation, Cholestasis, Balloon Dilatation	Altered Intercellular Communication	Older age, male sex, larger derangement of serum biochemistry, high serum bilirubin, AST/ALT > 1, more ballooning degeneration, portal inflammation, Mallory's hyaline, hepatocytic and ductular cholestasis, ductular proliferation and higher stage of fibrosis favors a diagnosis of ASH.	20699492
Inflammation, Fatty degeneration, Fatty Liver Disease	Altered Intercellular Communication	Younger age, high ALT, AST/ALT < 1, higher grade of steatosis and absence of extensive neutrophilic portal inflammation favors a diagnosis of NASH.	20699492
Inflammation, Ischemia	Altered Intercellular Communication	High-mobility group protein box-1 (HMGB1) has recently been recognized as a novel candidate in a specific upstream pathway promoting inflammation after brain ischemia.	20700129
Inflammation, Squamous cell carcinoma, SERPINB3 wt Allele	Altered Intercellular Communication	To study the main processes involved in oral squamous cell carcinoma (OSCC): apoptosis and inflammation.	20701075
glycation, vascular inflammations	Altered Intercellular Communication	The receptor for advanced glycation endproducts (RAGE) regulates vascular inflammation and atherogenesis.	20701913
Inflammatory abnormality of the eye, Ocular syphilis	Altered Intercellular Communication	All patients with ocular syphilis exhibited functional improvement and resolution of ocular inflammation after a specific antibiotic treatment.	20703496
Inflammation, Fibrosis Assessment, Lymphoid hyperplasia	Altered Intercellular Communication	Pathologic examination revealed chronic inflammation (n= 178), fibrosis without inflammation (n= 19), normal mucosa (n= 4), and lymphoid hyperplasia (n= 1).	20704489
Carcinoma, Basosquamous, Granulomatous inflammation, Chronic leukemia (category), Lymphoproliferative Disorders	Altered Intercellular Communication	Three patients had abnormal pathology: Lymphoproliferative disease in the patient with chronic leukemia, granulomatous inflammation, and basosquamous cell carcinoma.	20704489
vascular inflammations	Altered Intercellular Communication	Imaging of vascular inflammation with [11C]-PK11195 and positron emission tomography/computed tomography angiography.	20705222
vascular inflammations	Altered Intercellular Communication	By binding to activated macrophages in the vessel wall, [11C]-PK11195 enables noninvasive imaging of vascular inflammation.	20705222
Keratitis, Corneal edema	Altered Intercellular Communication	Besides central corneal edema, no other signs of corneal inflammation were detected.	20705342
Inflammation, Overweight	Altered Intercellular Communication	Chronic inflammation is associated with overweight in Colombian school children.	20705440
Inflammation, Periodontitis, Gingival Hemorrhage	Altered Intercellular Communication	Periodontal disease markers (extent of gingival bleeding, pocket depth, and loss of attachment, and a case definition of periodontitis) were associated on the arterial blood pressure outcomes through a series of regression models, incrementally adjusting for confounders (demographic, inflammation markers, chronic conditions, smoking, BMI, socio-economic status).	20706132
Inflammation, Hypertension, CTCAE, Gingival Hemorrhage	Altered Intercellular Communication	Gingival bleeding, a marker of current periodontal inflammation, was the only measure consistently and significantly associated with raised SBP and an increased odds of hypertension in the US adult population throughout the adjustment process.	20706132
Inflammatory, Inflammation	Altered Intercellular Communication	Spastic inflammatory entropion disappears with successful treatment of the inflammation.	20706724
Cicatricial entropion, Inflammation, Traumatic injury	Altered Intercellular Communication	Finally, cicatricial entropion can occur as a consequence of persistent inflammation or injuries.	20706724
Cessation of life, Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	Besides the inflammation, the Fas/Fas ligand (FasL)/caspase death pathway is documented to be activated in atherosclerotic lesions.	20707047
Inflammation	Altered Intercellular Communication	[Chronic low-grade inflammation, lipid risk factors and mortality in functionally dependent elderly].	20707051
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The fact that cytokines have the ability to induce its synthesis and release, creates a dynamic loop for self-preservation and augmentation of the airway inflammation in Chronic Obstructive Pulmonary Disease (COPD), even after the ceasing of the noxious stimulus, i.e., cigarette smoke.	20707291
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	Inflammation plays an essential role in the development and progression of atherosclerotic lesions.	20709104
Airway structure, Asthma	Altered Intercellular Communication	Studies using allergen challenge models have suggested Th2 cytokines promote airway inflammation in asthma.	20709516
Airway structure, Asthma	Altered Intercellular Communication	We assessed mediators of airway inflammation during the chronic asymptomatic phase of asthma.	20709516
Airway structure, Inflammation, Asthma	Altered Intercellular Communication	Baseline airway inflammation of intrinsic and extrinsic asthma is characterized by eosinophilic inflammation and the Th1 cytokine, IFN-gamma.	20709516
Vasculitis	Altered Intercellular Communication	Recent evidence suggests that chronic vascular inflammation ensues as an imbalance between pro- and anti-inflammatory mediators.	20709806
Inflammation	Altered Intercellular Communication	Recently identified lipid mediators (eg, lipoxins and resolvins) play active roles in promoting the resolution of inflammation.	20709806
Peripheral Arterial Diseases, Vascular System Injuries	Altered Intercellular Communication	These results also suggest that peripheral artery disease is associated with an inflammation-resolution deficit and highlight a potential therapeutic opportunity for the regulation of vascular injury responses.	20709806
Skin Papule, Staphylococcus, coagulase positive	Altered Intercellular Communication	Staphylococcus coagulase-positive skin inflammation associated with epidermal growth factor receptor-targeted therapy: an early and a late phase of papulopustular eruptions.	20709888
Rheumatoid Arthritis, Inflammation, Torticollis	Altered Intercellular Communication	Torticollis due to acute rheumatoid arthritis or other inflammation around the neck.	20711828
Inflammation, Osteopenia	Altered Intercellular Communication	In the 36-month observation period, there were no incidences of implant failure, excessive bone loss around implants, or peri-implant inflammation.	20712440
Inflammation, Precocious atherosclerosis, Cardiovascular Diseases, Refractory anemias, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Endothelial dysfunction	Altered Intercellular Communication	In this study we aimed to investigate whether there are indications of premature atherosclerosis, as measured by endothelial dependent flow-mediated dilation (ED-FMD) and intima media thickness (IMT), in patients with very early RA, and to analyze its relation to biomarkers of endothelial dysfunction, taking inflammation and traditional cardiovascular disease (CVD) risk factors into account.	20712865
Inflammation, Hypoxia, Obesity	Altered Intercellular Communication	Regional differences among adipose depots in capacities for fatty acid storage, susceptibility to hypoxia, and inflammation likely contribute to complications of obesity.	20713685
Inflammation, Hypoxia	Altered Intercellular Communication	VAT-EC may contribute to hypoxia and inflammation in VAT.	20713685
Pulmonary arterial hypertension, Inflammation, Polycyclic Hydrocarbons, Aromatic	Altered Intercellular Communication	Inflammation is a feature of pulmonary arterial hypertension (PAH), and increased circulating levels of cytokines are reported in patients with PAH.	20713898
Intraocular inflammation, Uveitis	Altered Intercellular Communication	56 eyes of 44 patients with intraocular inflammation were consecutively recruited from the uveitis clinic over 9 months.	20714184
Intraocular inflammation, Panuveitis, Uveitis	Altered Intercellular Communication	The degree of intraocular inflammation was recorded according to the Standardization of Uveitis Nomenclature criteria and the eyes were grouped as having anterior, intermediate, posterior or panuveitis.	20714184
Dyspnea, Bronchitis	Altered Intercellular Communication	Acute exacerbations of chronic bronchitis (AECB) are defined as recurrent attacks of worsening bronchial inflammation that are marked by an increase in the volume of daily sputum produced, a change in color of the expectorated sputum, and worsening dyspnea.	20714379
Vascular Diseases, vascular inflammations, Mitochondrial abnormalities	Altered Intercellular Communication	This review focuses on mitochondrial abnormalities that occur in the vasculature during aging and explores the link between mitochondrial oxidative stress, chronic low-grade vascular inflammation, increased rate of endothelial apoptosis, and development of vascular diseases in the elderly.	20714704
Inflammation, Pathology	Altered Intercellular Communication	NADPH oxidase/dual-oxidase (Nox/Duox) family members have been implicated in nuclear factor kappa-B (NFkB)-mediated inflammation and inflammation-associated pathologies.	20715105
Orbital Pseudotumor	Altered Intercellular Communication	The authors describe 2 cases of orbital xanthogranulomatous disease associated with an increase in IgG4-positive plasma cells, and also examine IgG4 in other types of orbital inflammation.	20716008
Necrobiotic Xanthogranuloma, Lipogranuloma, Mycoses, Orbital Pseudotumor, Chronic dacryoadenitis	Altered Intercellular Communication	Immunohistochemistry for total IgG and IgG4 was performed in 18 cases of orbital inflammation, including chronic dacryoadenitis (n=10), necrobiotic xanthogranuloma (n=2), xanthogranuloma (n=1), idiopathic orbital inflammation/pseudotumor (n=4), and fungal infection (n=1).	20716008
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Detection of hydrogen sulfide in plasma and knee-joint synovial fluid from rheumatoid arthritis patients: relation to clinical and laboratory measures of inflammation.	20716297
Inflammation, Swelling	Altered Intercellular Communication	Pharmacological inhibition of H(2)S synthesis reduces inflammation and swelling, suggesting that H(2)S is a potential inflammatory mediator.	20716297
Inflammation	Altered Intercellular Communication	SF H(2)S levels correlated with clinical indices of disease activity (tender joint count, r= 0.651; P < 0.05) and markers of chronic inflammation; Europhile count (r=-0.566; P < 0.01) and total white cell count (r=-0.703; P < 0.01).	20716297
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP), a biomarker of inflammation, has been associated with increased risk of developing cardiovascular disease.	20716378
Communicable Diseases, Epithelial cell abnormality, Inflammation	Altered Intercellular Communication	According to the revised Bethesda system, epithelial cell abnormality was found in 7 (2.9%), inflammation in 55 (22.8%), and infection in 9 (3.7%) patients.	20716829
Primary malignant neoplasm	Altered Intercellular Communication	The relationship between the presence and site of cancer, an inflammation-based prognostic score and biochemical parameters.	20717110
Primary malignant neoplasm	Altered Intercellular Communication	Therefore, to definitively examine the interrelationships between the above biochemical parameters, the mGPS and the presence of cancer, the Glasgow Inflammation Outcome Study was undertaken.	20717110
Inflammation, Malignant neoplasm of ovary, Neoplasms	Altered Intercellular Communication	These findings demonstrate that in ovarian carcinomas the unspecific "cancer-related inflammation" contributes to a significant subversion of the adaptive antitumor immune defense mounted at the tumor site.	20717669
Inflammation, Carcinogenesis	Altered Intercellular Communication	Chronic inflammation and subsequent tissutal alterations may play a key role in prostate carcinogenesis.	20717995
Primary malignant neoplasm	Altered Intercellular Communication	In this way, molecular alterations of the suppressor of cytokine signaling 3 (SOCS3), one of the most important inhibitory molecule of inflammatory signal transduction circuitries, could contribute to explain the pleiotropic role of interleukin-6 (IL-6) in this type of cancer.	20717995
Inflammation, Transmural, Hypertrophy	Altered Intercellular Communication	Light microscopic histopathologic analysis revealed acute greater than chronic inflammation, transmural edema, ischemia/necrosis of the intussusceptum, and hypertrophy of the intussuscipiens.	20718327
Inflammation, Nasopharyngeal carcinoma, Breast Carcinoma Metastatic in Lymph Node	Altered Intercellular Communication	To investigate the f variant of Epstein-Barr virus (EBV) in nasopharyngeal carcinogenesis, we detected the f variant in primary nasopharyngeal carcinoma (NPC), metastatic carcinoma of the lymph node (LN), and chronic inflammation of the nasopharynx from the Guangdong region.	20718717
Inflammation	Altered Intercellular Communication	However, only one demonstrated the F/f variant in 50 cases of chronic inflammation of the nasopharynx.	20718717
Nephritis, Lupus Nephritis	Altered Intercellular Communication	Together, these findings indicated that uMSCs were effective in decreasing renal inflammation and alleviating experimental lupus nephritis by inhibiting lymphocytes, inducing polarization of Th2 cytokines, and inhibition of proinflammatory cytokines production rather than direct engraftment and differentiating into renal tissue.	20719085
Inflammation, Sample Size Calculation, Arthropathy	Altered Intercellular Communication	Arthropathy, particularly synovial inflammation in SSc, is not well characterized.	20719883
Arthralgia, Inflammation, Sample Size Calculation	Altered Intercellular Communication	We explored the role of MRI and musculoskeletal ultrasonography (MSUS) in detecting and characterizing synovial inflammation in SSc patients with arthralgia while comparing the two imaging modalities.	20719883
Inflammation, Sample Size Calculation	Altered Intercellular Communication	While both MRI and MSUS are useful in characterizing synovial inflammation in SSc, MRI is clearly more sensitive than MSUS in this setting.	20719883
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Excessive aortic inflammation in chronic obstructive pulmonary disease: an 18F-FDG PET pilot study.	20720052
ARCN1 gene, vascular inflammations	Altered Intercellular Communication	We measured vascular inflammation in both COPD patients and controls using (18)F-FDG PET/CT.	20720052
ARCN1 gene, Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Aortic inflammation was expressed as the target-to-background ratio (TBR) of the standardized uptake value in 7 COPD patients, 5 metabolic syndrome patients, and 7 ex-smokers.	20720052
ARCN1 gene, Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	COPD patients exhibited aortic inflammation that fell between the aortic inflammation exhibited by ex-smokers and that by metabolic syndrome patients.	20720052
Acute inflammation of orbit	Altered Intercellular Communication	There were 530 cases admitted with acute orbital inflammation over a 9-year period from 1 July 2000 to 30 June 2009.	20720603
Refractory anemias, Communicable Diseases, musculoskeletal infection	Altered Intercellular Communication	The usefulness of neutrophil CD64 expression (CD64) to diagnose local musculoskeletal infection (local infection) and discriminate local infection from RA-related inflammation in RA patients was examined.	20721724
Refractory anemias, Communicable Diseases, High Affinity Immunoglobulin Gamma Fc Receptor I, human	Altered Intercellular Communication	CD64 is a useful marker in RA patients to discriminate local infection from RA-related inflammation.	20721724
Inflammation	Altered Intercellular Communication	However, subsequent examination revealed a chronic IgG4-associated, lymphoplasmatic sclerosing inflammation of the biliary tract.	20721841
vascular inflammations, Leucocytic infiltrate	Altered Intercellular Communication	The severity of inflammatory cell infiltration around the fascial and intramuscular small blood vessels was evaluated using the total vascular inflammation score (TVIS).	20722021
Inflammation, "Crohns disease of large bowel	Altered Intercellular Communication	Which magnetic resonance imaging findings accurately evaluate inflammation in small bowel Crohn's disease?	20722053
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The inflammation score correlated with the fibrosis score (r = 0.63, P = 0.0001).	20722053
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We also showed that fibrosis was closely and positively related to inflammation.	20722053
Inflammation, Fatigue	Altered Intercellular Communication	Mechanisms probably contributing to fatigue in older adults include decline in mitochondrial function, alterations in brain neurotransmitters, oxidative stress, and inflammation.	20722821
Inflammation, Fatigue	Altered Intercellular Communication	Mechanisms probably contributing to fatigue in older adults include decline in mitochondrial function, alterations in brain neurotransmitters, oxidative stress, and inflammation.	20722821
Inflammation, Eustachian tube disorder	Altered Intercellular Communication	For long-term success in implantation of the IHA, careful control of middle ear inflammation and measures against eustachian tube dysfunction are required in addition to technological advancements.	20723782
Inflammation	Altered Intercellular Communication	PFS is characterised in its early stages by local inflammation with beginning ulceration and can be managed conservatively.	20724234
APP gene, Inflammation	Altered Intercellular Communication	Lower extremity exercise improves aortic hemodynamics and reduces inflammation, but the safety and efficacy of exercise training in AAA disease is unknown.	20724934
Inflammation, Adrenal Gland Hyperfunction, Cardiovascular Diseases	Altered Intercellular Communication	The frailty syndrome is associated with inflammation, hypercortisolemia, and cardiovascular diseases, all of which are linked with insulin resistance.	20725120
Hypermetabolism, Inflammation, Weight decreased, Adrenal Gland Hyperfunction	Altered Intercellular Communication	We wondered whether hypermetabolism associated with inflammation and hypercortisolemia could increase the thermic effect of food (TEF) and contribute to the frailty-associated body weight loss.	20725120
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Relevance of lower airway bacterial colonization, airway inflammation, and pulmonary function in the stable stage of chronic obstructive pulmonary disease.	20725845
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease, Active Breathing Control	Altered Intercellular Communication	The objective of this investigation was to verify the hypothesis that the presence of lower airway bacterial colonization (LABC) can be a stimulating factor of airway inflammation, more frequent exacerbation, and impact on pulmonary function, independent of current tobacco smoking in the stable phase of chronic obstructive pulmonary disease (COPD).	20725845
ARCN1 gene, Active Breathing Control, Airway structure	Altered Intercellular Communication	LABC was documented in a subpopulation of stable COPD patients; it may be responsible for the deterioration of pulmonary function of COPD patients by promoting airway inflammation and/or increased frequency of exacerbations independently of tobacco smoking.	20725845
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Intra-operative findings consisted in both cases in tumor-like appendiceal abscesses, situated behind ileocecal junction, with local inflammation and fibrosis, suggesting a long-term evolution.	20726309
Inflammation	Altered Intercellular Communication	CC chemokine receptors (CCR) have an important role in the recruitment of leukocytes to the site of inflammation.	20726319
Colorectal Carcinoma, Neoplasms	Altered Intercellular Communication	Toll-like receptor (TLR) 7 and TLR8 expression on CD133+ cells in colorectal cancer points to a specific role for inflammation-induced TLRs in tumourigenesis and tumour progression.	20728343
Inflammation, Primary malignant neoplasm, Carcinogenesis	Altered Intercellular Communication	Toll-like receptor (TLR) stimulation results in activation of NF-kB, a key modulator in driving inflammation to cancer and mitogen-activated protein kinases that have been shown to recruit mitotic and cyclooxygenase-2 (COX-2) induced pathways in carcinogenesis.	20728343
Coinfection, Periodontitis, Gram Negative Bacteria	Altered Intercellular Communication	Apical periodontitis is a polymicrobial inflammation with a dominant flora of opportunistic Gram-negative bacteria; however, a pathogenic role of human herpesviruses such as Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) has been implicated recently.	20728714
Inflammation, platelet dysfunction	Altered Intercellular Communication	Furthermore, a state of low-grade chronic inflammation can promote increased oxidative stress and lead to endothelial cell and platelet dysfunction ultimately contributing to thrombogenesis.	20728920
Inflammation, Acute Kidney Insufficiency	Altered Intercellular Communication	Complications associated with mortality included: acute renal impairment (OR 3.3 (95% CI 2.1-5.0), p < 0.001); unplanned Intensive Care Unit admission (OR 3.1 (95% CI 1.9-4.9), p < 0.001); and systemic inflammation (OR 2.5 (95% CI 1.7-3.7), p < 0.001).	20731639
Hepatitis, Chronic	Altered Intercellular Communication	This would facilitate a fast response, probably controlled by IL-6, against repeated bacterial-DNA translocation or in liver chronic inflammation.	20731703
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) may be related to chronic inflammation and immune-mediated conditions, and its pathogenesis involves T-cell activation and proliferation.	20732370
Inflammation, Periodontal Diseases, Atherosclerosis	Altered Intercellular Communication	The link between periodontal disease and atherosclerosis has not yet been clarified, though systemic inflammation seems to be the common soil for both conditions.	20732683
Inflammation, Exanthema	Altered Intercellular Communication	We found a lower inhibition of epidermal kinetics and decreased inflammation in HER1/2i-induced rash.	20732960
Inflammation	Altered Intercellular Communication	Increased levels of inflammation among women with enlarged waist and elevated triglyceride concentrations.	20733290
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	We have evaluated the association between hypertriglyceridemic waist (HW) phenotype, markers of systemic inflammation and endothelial dysfunction in women.	20733290
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	This study provides evidence showing a positive association between HW phenotype and markers of systemic inflammation and endothelial dysfunction.	20733290
Cessation of life, Inflammation	Altered Intercellular Communication	Does association with volume status and inflammation account for the increased death risk from high peritoneal protein clearance in peritoneal dialysis?	20733298
Inflammation, Fluid overload	Altered Intercellular Communication	To determine if the association between high peritoneal protein clearance (PrC) and increased all-cause mortality is explained by inflammation and volume overload in continuous ambulatory peritoneal dialysis patients.	20733298
Inflammation, Fluid overload	Altered Intercellular Communication	A high PrC was associated with more severe inflammation and volume overload.	20733298
Inflammation, Fluid overload	Altered Intercellular Communication	Peritoneal PrC, although correlated with volume overload and inflammation, is largely an independent predictor of mortality.	20733298
Delirium, Cessation of life	Altered Intercellular Communication	The effect of delirium on the cause of death might be explained by an aggravation of an ongoing neuro-inflammation.	20733304
eosinophil, Inflammation, Nasal Polyps	Altered Intercellular Communication	Nasal polyps develop as a result of chronic inflammation, mostly accompanied by pronounced eosinophil leukocyte infiltration.	20734966
Inflammation, Prostate carcinoma, Structure of posterior cerebral artery	Altered Intercellular Communication	Recent studies identified an increased risk of prostate cancer (PCa) in Caucasian men harboring polymorphisms of genes involved in innate immunity and inflammation.	20735825
Inflammation, Calcinosis, Heart valve disease	Altered Intercellular Communication	It is possible that the lower plasma concentration of TGF-b1 in patients with valvular heart disease and the lack of its regulatory effect results in the increased inflammation and calcification seen in DHVs.	20736227
Pneumonia, Carcinogenesis, Infection, Carcinoma of lung, Pneumonitis	Altered Intercellular Communication	The increased lung cancer risk associated with recurrent pneumonia supports the hypothesis that chronic pulmonary inflammation arising from infections contributes to lung carcinogenesis.	20736841
Disturbance, Inflammation, Eye Abnormalities, Pain Distress Question	Altered Intercellular Communication	Outcome measures included return of normal vision, absence of motility disturbance, and resolution of pain, inflammation, eyelid abnormalities, and other symptoms.	20736875
Inflammation	Altered Intercellular Communication	COMP is the first extracellular matrix protein for which an active role in inflammation has been demonstrated in vivo.	20737467
Inflammation, Necrosis	Altered Intercellular Communication	A noninvasive procedure was devised to diagnose the termination of an inflammatory process in the necrotic process in MI, which implies the determination of salivary ceruloplasmin, if the latter is less than 106 mg/l, inflammation completeness in the necrotic area is diagnosed.	20737674
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	The wrist is almost invariably affected in rheumatoid arthritis (RA) and inflammation of the wrist can lead to impaired function and eventually to severe destruction.	20738208
Inflammation, Arthritis of wrist, Swelling, Pain Distress Question	Altered Intercellular Communication	Classical signs of inflammation, pain, swelling and heat may often be observed in clinical examination of wrist arthritis and in ultrasound (US) investigation.	20738208
Refractory anemias, Inflammation	Altered Intercellular Communication	Correlation coefficients between clinical and ultrasound parameters of RA wrist inflammation in this study were fair to moderate.	20738208
Inflammation, Pain Distress Question, Erythema, Swelling, Renal Insufficiency, Arthritis	Altered Intercellular Communication	The classical signs of inflammation (pain, swelling, redness, heat and impaired function) seem to reflect different aspects of arthritis.	20738208
Refractory anemias, Inflammation, destruction joint, Rheumatoid Factor	Altered Intercellular Communication	Monocytes/macrophages accumulate in the rheumatoid (RA) synovium where they play a central role in inflammation and joint destruction.	20738854
Gastritis	Altered Intercellular Communication	The results suggest an angiotensin II mediated impact on mucosal epithelial functions, antral endocrine properties, microvascular permeability, and gastric inflammation.	20739374
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The oxidative stress becomes evident as a result of accumulation of ROS in conditions of inflammation and Type 2 diabetes mellitus (T2DM).	20739761
Inflammation, Demyelination, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	Altered Intercellular Communication	In resource-restricted settings where these techniques are not freely available, it is useful to determine the utility of 'supportive' pathologic criteria (subperineurial edema, inflammation, onion bulb formation, and demyelination) proposed by AAN for diagnosis of CIDP.	20739789
Inflammation, Demyelination	Altered Intercellular Communication	Frequency of specific pathological alterations such as demyelination, inflammation, onion bulb formation, and axonal changes in sural nerve biopsies was evaluated.	20739789
Inflammation	Altered Intercellular Communication	Endoneurial inflammation was frequent in the relapsing-remitting form and epineurial inflammation and axonal changes in those with progressive course.	20739789
Inflammation, Pneumonia	Altered Intercellular Communication	Osteopontin is likely to contribute to the development of inflammation in patients with eosinophilic pneumonia.	20796249
Inflammation, Obesity	Altered Intercellular Communication	Inflammation and obesity are associated with AF, but the relationship between AF and pericardial fat is unknown.	20797492
Inflammation, Atherosclerosis, Cardiovascular Diseases, Diabetes Mellitus, Obesity	Altered Intercellular Communication	Excess secretion of various adipocyte-derived molecules has been linked with insulin resistance, obesity, diabetes, inflammation, atherosclerosis, and cardiovascular disease.	20798476
Inflammation	Altered Intercellular Communication	Markers of chronic inflammation with short-term changes in physical activity.	20798662
Inflammation, Behavior	Altered Intercellular Communication	Regular exercise is inversely related to markers of chronic inflammation, but we do not know to what extent these changes are the product of recent exercise behavior.	20798662
Inflammation, Hydronephrosis	Altered Intercellular Communication	In patients with acute inflammation or hydronephrosis individual treatment concepts are required.	20799024
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	We have recently reported that HMGB1 is released by osteoarthritic synoviocytes after activation with interleukin-1beta (IL-1b) The present study investigated the role of HMGB1 in synovial inflammation in osteoarthritis (OA).	20799933
Inflammation, Guillain-Barre Syndrome, Familial	Altered Intercellular Communication	We observed a major sensitivity to carbonylation for albumin and alpha-glycoprotein in inflammation and a selective increase of reactivity for a glycosylated Fab from an IgM globulin in GBS CSF.	20801190
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) therapy is complicated by corticosteroid resistance of the interleukin 8 (IL-8)-dependent and granulocyte macrophage-colony stimulating factor (GM-CSF)-dependent chronic airway inflammation, for whose establishment human airway smooth muscle cells (HASMCs) might be crucial.	20801891
Inflammation, Papilledema	Altered Intercellular Communication	This condition is due to inflammation of the optic nerve sheath and is often mistaken for papilledema or papillitis.	20802364
Cellulite, Lymphangitis, Inflammation, Necrosis	Altered Intercellular Communication	Inflammation, dehiscence, cellulites, lymphangitis, drainage, necrosis, or abscess necessitating dressing, antibiotics or debridement before complete healing without eschar were defined as wound complications.	20802911
Colitis	Altered Intercellular Communication	Derivation of a T2-weighted MRI total colonic inflammation score (TCIS) for assessment of patients with severe acute inflammatory colitis-a preliminary study.	20803202
Trachoma , Perifolliculitis	Altered Intercellular Communication	The prevalence of trachomatous inflammation-follicular (TF) among children was 1.32% [95% CI, 0.77-1.86] in Gatsibo and 0.73% 195% CI, 0.33-1.13] in Nyaruguru Districts, respectively; with both districts having a prevalence below the WHO/International Trachoma Initiative (ITI) cut-off point of 10% for trachoma to be taken as disease of public health importance.	20803920
Osteomyelitis, Diabetes Mellitus	Altered Intercellular Communication	[Modulation of platelet tyrosine phosphatases by arachidonic acid metabolites in diabetes mellitus complicated with acute pyogenic inflammation].	20804071
Inflammation, Heart failure	Altered Intercellular Communication	These data provide further evidence for an association between chronic inflammation and the development of heart failure.	20804707
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Osteopontin (OPN) is a glycoprotein that has been associated with inflammation and fibrosis.	20805171
Inflammation, Rheumatoid Arthritis, Osteopenia	Altered Intercellular Communication	Effect of intra-articular corticosteroid injections and inflammation on periarticular and generalised bone loss in early rheumatoid arthritis.	20805297
Refractory anemias, Inflammation	Altered Intercellular Communication	These data emphasise the importance of suppressing inflammation in patients with active RA to maintain bone health.	20805297
Inflammation, Cardiac complication, Diabetes Mellitus, GDC Disease Response Terminology	Altered Intercellular Communication	Persons with diabetes who had higher levels of CRP and BMI were less likely to have DR. Further research is needed to understand the interrelationship role of inflammation, body weight, and microvascular complications.	20805569
Inflammation, Malnutrition, Cardiovascular Diseases	Altered Intercellular Communication	In patients without cardiovascular disease, malnutrition and inflammation were associated with vascular prostheses, while pro-BNP was lower in obese patients.	20805692
Steatohepatitis, Inflammation, Fatty Liver Disease	Altered Intercellular Communication	These findings point toward the possible influence of age in the severity of steatohepatitis, portal and lobar inflammation in patients suffering from NASH while gender independently might contribute to the level of steatohepatitis.	20806434
Inflammation, Degenerative polyarthritis, Degenerative aortic valve disease, Age related macular degeneration, Autolysosome	Altered Intercellular Communication	To examine the relationship between degenerative aortic valve disease and osteoarthritis Background: Degenerative aortic valve disease (DAVD) and osteoarthritis (OA) are age-related degenerative diseases whose pathogenesis involves mechanical stress and local inflammation.	20806543
Inflammation, Secondary malignant neoplasm of liver	Altered Intercellular Communication	Liver metastases are present in many of these patients and some of them may display significant systemic inflammation.	20806616
Inflammation, Fibrosis Assessment, Tissue Adhesions	Altered Intercellular Communication	Inflammation and subsequent fibrosis, adhesions, or plicae may limit normal capsular compliance and decrease volume capacity of the knee.	20807861
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Magnesium intake in relation to systemic inflammation, insulin resistance, and the incidence of diabetes.	20807870
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	To investigate the long-term associations of magnesium intake with incidence of diabetes, systemic inflammation, and insulin resistance among young American adults.	20807870
Pulmonary arterial hypertension, Inflammation, Vascular System Injuries	Altered Intercellular Communication	Limited systemic sclerosis patients with pulmonary arterial hypertension show biomarkers of inflammation and vascular injury.	20808962
Inflammation, Vascular System Injuries	Altered Intercellular Communication	The gene expression and cytokine profiles of lSSc-PAH patients suggest the presence of activated monocytes, and show markers of vascular injury and inflammation.	20808962
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Association between cystatin C and inflammation in patients with essential hypertension.	20809110
Renal Insufficiency, Inflammation	Altered Intercellular Communication	It is known that the initiation and progression of these cardiovascular events contributes to renal dysfunction and chronic inflammation.	20809110
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	Inflammation plays an important role in the pathophysiology of both atherosclerosis and type 2 diabetes and some inflammatory markers may also predict the risk of developing type 2 diabetes.	20809989
Inflammation, Functional Disability, Inflammatory polyarthritis	Altered Intercellular Communication	To assess the impact of the knee joint inflammation, detected by ultrasonography (US), on functional disability in patients with recent-onset inflammatory polyarthritis (IP).	20810032
Inflammation, Synovial Hypertrophy, Synovial Fluid	Altered Intercellular Communication	Joint group involvement was defined when at least one joint showed intra-articular signs of inflammation (synovial fluid abnormalities and/or synovial hypertrophy), according to the OMERACT definitions.	20810032
Inflammation	Altered Intercellular Communication	The mean difference of HAQ between patients with and without US knee inflammation was 0.42 (95%CI 0.22, 0.62; p<0.001).	20810032
Inflammation, Ulcer	Altered Intercellular Communication	After detailed history every patient underwent a comprehensive ophthalmic slit lamp bio-microscopical examination, for characteristics of the ulcer to locate the site, size, depth of ulcer and anterior chamber inflammation.	20810053
Inflammation, Nasal Polyps, Asthma	Altered Intercellular Communication	Nasal polyps from 70 Belgian patients, 34% with asthma, were analyzed for type of inflammation, T-cell cytokines, and IgE antibodies to Staphylococcus aureus enterotoxins.	20810157
Inflammation, Nasal Polyps	Altered Intercellular Communication	Mucosal inflammation in nasal polyps orchestrated by T(H)2 cytokines and amplified by S aureus enterotoxins is characterized by an increased eosinophilic inflammation and formation of IgE antibodies.	20810157
Inflammation, Bacterial sepsis	Altered Intercellular Communication	Elevated serum cytokines correlate with inflammation but are of limited use to differentiate between active AOSD and bacterial sepsis.	20810496
Airway structure, Inflammation	Altered Intercellular Communication	A total of 60 elderly subjects contributed up to 12 weekly measurements of fractional exhaled nitric oxide (NO; airway inflammation biomarker), and plasma interleukin-6 (IL-6; systemic inflammation biomarker).	20811287
Inflammation, Hematoma, Hemorrhage, Communicable Diseases, Postoperative Complications, Reactive Cutaneous Fibrous Lesion	Altered Intercellular Communication	We compared local tissue inflammation and fibrous reaction, postoperative complications (bleeding, wound haematoma, wound infection) and postoperative recovery time (time of mobilisation) in rats (Fischer strain) after implantation of a polypropylene mesh (PPM) (Prolene, Ethicon, Bracknell, UK) or a dual component fibrin mesh (DCFM) (Tachosil, Nycomed, Marlow, UK), between the muscle layer and the fascia transversalis defect.	20811761
Inflammation, Psychiatric	Altered Intercellular Communication	Interferon-gamma-inducible kynurenines/pteridines inflammation cascade: implications for aging and aging-associated psychiatric and medical disorders.	20811799
Inflammation, Impaired cognition, Metabolic Syndrome X, Depression, CTCAE, Mental disorders	Altered Intercellular Communication	This review of literature and our data suggests that up-regulated production of interferon-gamma (IFNG) in periphery and brain triggers a merger of tryptophan (TRY)-kynurenine (KYN) and guanine-tetrahydrobiopterin (BH4) metabolic pathways into inflammation cascade involved in aging and aging-associated medical and psychiatric disorders (AAMPD) (metabolic syndrome, depression, vascular cognitive impairment).	20811799
Arterial Stiffness, Inflammation	Altered Intercellular Communication	In long-term normoalbuminemic Japanese hemodialysis patients, with low prevalence of inflammation, OPG levels were strongly linked with both arterial stiffness and worse outcome.	20812007
Vasculitis, CTCAE, Interstitial inflammation, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Histology of a surgical lung biopsy showed interstitial inflammation, vasculitis and non-caseating granulomas.	20812157
Rheumatoid Arthritis, Atlanto-Axial joint, Inflammation, Neck Pain	Altered Intercellular Communication	Rheumatoid arthritis involving the atlanto-axial region should be considered in patients with persisting neck pain and signs of inflammation.	20812156
Inflammation, Musculoskeletal Pain	Altered Intercellular Communication	Polymyalgia rheumatica (PMR) is characterized by aching of the proximal muscles and increased blood levels of markers of inflammation.	20812339
Inflammation, Muscle complaint	Altered Intercellular Communication	Despite the muscle complaints, the current view is that symptoms are caused by inflammation in synovial structures.	20812339
Inflammation, Fibrosis Assessment, Lymphoma, Pseudolymphoma	Altered Intercellular Communication	Histopathologic findings included: chronic inflammation in 450 patients (95.5%), fibrosis in 18 patients (3.8%), lymphoma in two patients (0.4%) and reactive lymphoid hyperplasia in one patient (0.2%).	20812824
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Chronic inflammation and fibrosis are the most common histopathologic findings in lacrimal sac specimens obtained during DCR.	20812824
Autoimmune Diseases, Keratitis, Herpetic, Inflammatory abnormality of the eye	Altered Intercellular Communication	Cryptic ocular herpes may confound matters in someone with an autoimmune disease thought to be the sole source of ocular inflammation.	20812857
Inflammation	Altered Intercellular Communication	Inflammation, oxidative stress, and high concentration of serum lipoprotein (a) [Lp (a)] are common complications in hemodialysis patients.	20812958
Fibrous, Inflammation, Calcinosis, Dental Plaque	Altered Intercellular Communication	With increasing age, plaque calcification and large lipid core increased (P<0.001 and P=0.01, respectively) and fibrous tissue (P=0.01) decreased, but lymphocyte infiltration of the plaque (P=0.03) and cap (P=0.002) and overall plaque inflammation (P=0.03) also decreased such that overall plaque instability was unrelated to age.	20814007
Barrett Esophagus, Esophageal mucous membrane, Inflammation, Chronic esophagitis	Altered Intercellular Communication	Mixed reflux of the gastroduodenal contents induces the esophageal mucosal damage and inflammation progressing chronic esophagitis and premalignant Barrett's esophagus (BE).	20814068
Inflammation, Adenocarcinoma Of Esophagus	Altered Intercellular Communication	The role of cyclooxygenase-2 (COX-2) and chronic inflammation in the progression of BE toward adenocarcinoma of the esophagus has not been extensively studied in experimental models of BE in animals and in human subjects.	20814068
Inflammation, Malnutrition, Comorbidity	Altered Intercellular Communication	Various factors may contribute to malnutrition in these patients including energy and protein intake, inflammation, and comorbidity.	20814118
Airway structure, Asthma	Altered Intercellular Communication	Clinical correlates and determinants of airway inflammation in pediatric asthma.	20815308
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation is a key component in the pathophysiology of asthma.	20815308
Inflammation, Asthma	Altered Intercellular Communication	However, neither its role in the clinical features of asthma nor the factors affecting the degree of inflammation have been fully defined.	20815308
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation, as determined by FE(NO), is only weakly associated with the clinical expression of asthma and spirometry results.	20815308
Allergic, Inflammation, IL13 gene, Allergy - Charge Type Reason	Altered Intercellular Communication	Asthma is similarly associated with allergic and nonallergic rhinitis, suggesting a link between upper and lower airways beyond allergy associated inflammation.	20816191
Degenerative polyarthritis, Inflammation, Nasal cartilage loss	Altered Intercellular Communication	The role of inflammation in osteoarthritis (OA) pathogenesis is unclear, and the associations between inflammatory cytokines and cartilage loss have not been reported.	20816981
Degenerative polyarthritis, Inflammation, Nasal cartilage loss	Altered Intercellular Communication	Serum levels of IL-6 and TNF-a are associated with knee cartilage loss in older people suggesting low level inflammation plays a role in the pathogenesis of knee OA.	20816981
Inflammation, Periodontal Diseases, Atherosclerosis	Altered Intercellular Communication	The candidates contributing to atherosclerosis in periodontal disease include low-grade inflammation such as C-reactive protein (CRP) and insulin resistance.	20817211
Inflammation	Altered Intercellular Communication	Accumulation of LPC (1-acyl 16:0), PC (1-acyl 36:4) and SM (d18:1/16:0) in the VV tissues suggested that inflammation associated with abnormal lipid metabolism may contribute to the development of VV.	20817502
Inflammation, Albuminuria, Chronic Kidney Diseases	Altered Intercellular Communication	Vitamin D deficiency, inflammation, and albuminuria in chronic kidney disease: complex interactions.	20817560
Proteinuria, Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Although proteinuria is a marker of kidney and cardiovascular disease, few studies have examined vitamin D levels, inflammation, and proteinuria simultaneously in CKD.	20817560
Inflammation, Albuminuria	Altered Intercellular Communication	IL-6 may be an important intermediary between vitamin D deficiency and albuminuria, or vitamin D deficiency may contribute to inflammation and subsequent albuminuria.	20817560
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Therefore, we hypothesize that the LTB4 pathway plays an important role in the pathogenesis of neutrophilic inflammation that contributes to pulmonary emphysema.	20817777
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	Together, these findings demonstrated that LTB4 played an important role in promoting the pathogenesis of pulmonary emphysema associated with neutrophilic pulmonary inflammation.	20817777
Pain Distress Question, Fasciitis, Inflammation	Altered Intercellular Communication	Plantar fasciitis is commonly treated with corticosteroid injections to decrease pain and inflammation.	20817847
Inflammation, Duodenal atrophy	Altered Intercellular Communication	Duodenal dystrophy is a rare disease, characterized by the chronic inflammation of the aberrant pancreatic tissue in the duodenal wall.	20818113
Dystrophy, Inflammation	Altered Intercellular Communication	A diagnosis of cystic dystrophy of the vertical part of the duodenum without chronic inflammation of the orthotopic pancreas was established in both cases by multi-detector computed tomography, magnetic resonance imaging and endosonography.	20818113
Calcinosis, Chronic inflammation	Altered Intercellular Communication	Biopsies of walls of the orbital cyst showed fragments of neuroglial and meningothelial tissues with some calcification and mild chronic inflammation.	20818257
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Our findings suggest that in NOD mice serum TGF-b1 levels during the natural history of the diabetes reflect the course of islet inflammation.	20819089
Dystrophy, Myositis, Polymyositis, Muscular Dystrophy, Dermatomyositis	Altered Intercellular Communication	The study included 20 cases of definite polymyositis, 20 cases of dermatomyositis and 10 cases of dystrophies with muscle inflammation (inflammatory muscular dystrophy).	20819442
Dystrophy, Polymyositis, Myositis	Altered Intercellular Communication	The results suggest that MHC-I detection alone cannot be used as a reliable diagnostic test to differentiate polymyositis from dystrophies with secondary muscle inflammation.	20819442
Inflammation, Depression, CTCAE, Coronary heart disease	Altered Intercellular Communication	Glucocorticoid signaling exerts major roles in inflammation, metabolism and depression, which are three crucial factors accompanying or underlying coronary heart disease.	20819629
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	One RFA-treated metastasis with rim-shaped uptake was regarded as inflammation.	20819630
Inflammation, Adenocarcinoma of lung (disorder)	Altered Intercellular Communication	Up-regulation of the expression of S100A8 and S100A9 in lung adenocarcinoma and its correlation with inflammation and other clinical features.	20819668
Adenocarcinoma, Inflammation	Altered Intercellular Communication	The higher expression was found to be correlated with the clinical characteristics of adenocarcinoma, inflammation and stage IV lesion.	20819668
Inflammation, Primary malignant neoplasm, Stage I Lung Cancer AJCC v8, Adenocarcinoma of lung (disorder)	Altered Intercellular Communication	S100A8, S100A9 up-regulation was found in the lung adenocarcinoma and end stage lung cancer tissue, the correlation of which with their higher expression in inflammatory lung tissues may indicate the collaborative effect of inflammation on the progression of cancer.	20819668
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Portal inflammation is associated with advanced histological changes in alcoholic and non-alcoholic fatty liver disease.	20819880
Inflammation, Non-alcoholic Fatty Liver Disease, Chronic liver disease, Fatty Liver Disease	Altered Intercellular Communication	Fatty liver disease (FLD), of either alcoholic (AFLD) or non-alcoholic (NAFLD) aetiologies, is characterised histologically by features that are lobulocentric that typically affect zone 3, in contrast with portal-based inflammation characteristics of other forms of chronic liver disease.	20819880
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	The authors aimed to determine the prevalence and significance of portal inflammation in a cohort of adults diagnosed as having AFLD and NAFLD.	20819880
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	More than a mild degree of portal inflammation was found in 47% of AFLD compared with 30% in NAFLD subgroup.	20819880
Inflammation, Non-alcoholic Fatty Liver Disease, Hypertension, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	A higher degree of portal inflammation in AFLD was associated with a higher mean corpuscular volume, gamma glutamyl transferase (GGT) and alkaline phosphatase, and a lower platelet count and albumin, whereas in NAFLD this was associated with age, presence of diabetes, hypertension, body mass index (BMI), higher fasting blood glucose, cholesterol, alanine transaminase, GGT and ferritin.	20819880
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Fatty degeneration	Altered Intercellular Communication	On regression analysis, portal inflammation was associated with the severity of steatosis (p=0.005), presence of ballooning (p=0.030) in NAFLD and severity of fibrosis in both AFLD and NAFLD (p<0.001).	20819880
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Portal inflammation is a common component of histological spectrum of both AFLD and NAFLD.	20819880
Inflammation	Altered Intercellular Communication	In both conditions portal inflammation is associated with clinical and histological features suggestive of advanced disease.	20819880
Primary malignant neoplasm, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	Hepatocellular carcinoma (HCC) is a type of inflammation-related cancer that usually follows chronic inflammations.	20820981
Inflammation, Neoplasms	Altered Intercellular Communication	The levels of LTD4 were neither associated with parameters expressing tumor burden, such as AFP, nor with inflammation factors AST and g-GT.	20820981
Primary malignant neoplasm, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	Hepatocellular carcinoma (HCC) is a type of inflammation-related cancer that usually follows chronic inflammations.	20820981
Nutritional Deficiency, Inflammation, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	About one third of persons have anemia secondary to a nutritional deficiency, one third have anemia caused by chronic inflammation or chronic kidney disease, and one third have unexplained anemia.	20822082
Inflammation, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	Anemia of chronic inflammation or chronic kidney disease may respond to treatment of the underlying disease and selective use of erythropoiesis-stimulating agents.	20822082
Extrinsic allergic alveolitis, Inflammation, Ground Glass Opacity, Alveolitis	Altered Intercellular Communication	The CT scan appearance, showing mosaic ground-glass opacities in the ventilated parts of the lung, the centrolobular predominance of inflammation on the lung sections, and the presence of a lymphocytic alveolitis at BAL suggested a hypersensitivity pneumonitis.	20822994
Ischemia, Meningitis	Altered Intercellular Communication	These neuroimages of our patient supported that leptomeningeal inflammation and the adjacent cerebrocortical ischemia could cause encephalitis-like symptoms in RLM patients.	20823656
Inflammation, Villous atrophy	Altered Intercellular Communication	In 2006-2008, we collected duodenal/jejunal biopsy data on CD (Marsh 3: villous atrophy, VA; n=29,008 unique individuals) and inflammation (Marsh 1-2; n=13,200) from all 28 pathology departments in Sweden.	20823839
Inflammation, HIV Infections	Altered Intercellular Communication	However, markers of inflammation and platelet activation were not appreciably changed suggesting that the biologic properties of these agents differ in persons with HIV infection.	20824151
Inflammatory Bowel Diseases, Inflammation, Mesenteric Venous Thrombosis	Altered Intercellular Communication	Mesenteric thrombosis is a rare complication of IBD and may develop during clinical remission, suggesting a potential role for factors other than clinically significant inflammation in its pathogenesis.	20824370
Inflammation, diabetic	Altered Intercellular Communication	[A non-abscess-forming inflammation of the corpora cavernosa in a diabetic patient - case report].	20824577
Inflammation, Thrombosis, Neoplasms, Specimen Source Codes - Abscess, Corpus cavernosum structure, Embolism	Altered Intercellular Communication	An inflammation of the corpus cavernosum is relatively rare and must be differentiated from a tumour, abscess, thrombosis or embolism of the penile vessels.	20824577
Occluded, Corpus cavernosum structure, Inflammation, Infection	Altered Intercellular Communication	Most frequently inflammation of the corpus cavernosum is caused by iatrogenic interventions, followed by general infections and acute occlusion of penile vessels.	20824577
Inflammation, diabetic, Specimen Source Codes - Abscess	Altered Intercellular Communication	In the case of a 51-year-old diabetic patient with painful induration of the penis, an MR imaging study was undertaken to identify an inflammation of the corpora by exclusion of abscess formation.	20824577
Inflammation	Altered Intercellular Communication	The inflammation responded well to a two-week oral Fluorchinolon treatment.	20824577
Inflammation	Altered Intercellular Communication	Due to its high soft-tissue contrast, multiplanar layer images and, the MR scan was performed to identify an inflammation of the corpora cavernosa and to exclude an abscess formation.	20824577
Inflammation, Fracture, Osteoporosis, Crohn Disease	Altered Intercellular Communication	There is evidence to suggest that the inflammation associated with Crohn's disease (CD) impacts the bone health of patients, predisposing them to early onset osteoporosis and increasing their risk of fracture.	20824813
Inflammation	Altered Intercellular Communication	A liver biopsy showed well-preserved structures with minor signs of inflammation.	20824971
Orbital Pseudotumor, Pigment Epithelium	Altered Intercellular Communication	To present a rare idiopathic inflammation of the posterior segment of the eye - acute posterior multifocal placoid pigment epitheliopathy (APMPPE).	20825067
Inflammation, Asthma, Obesity	Altered Intercellular Communication	Obesity and asthma are characterized by the presence of inflammation.	20825465
Inflammation, Asthma, Obesity	Altered Intercellular Communication	We aimed to determine whether obesity influences asthmatic inflammation as well as the contribution of leptin or/and adiponectin to a possible linkage between asthmatic and obesity-related inflammation.	20825465
Airway structure, Inflammation, Bronchial Hyperreactivity, Obesity	Altered Intercellular Communication	Possible associations between variables expressing airway inflammation, bronchial hyper-responsiveness, systemic inflammation and obesity, as assessed by BMI, were evaluated.	20825465
Asthma	Altered Intercellular Communication	Alterations of leptin/adiponectin balance may be related to the presence of leukotriene inflammation in obese asthmatic patients.	20825465
Pain Distress Question, bone and joint infections, Myositis	Altered Intercellular Communication	A perirectal abscess as a cause of acute hip pain and inability to ambulate, with gluteus muscle inflammation but no evidence for bone or joint infection, has not been described, to the authors' knowledge.	20825909
Ischiorectal abscess, Abnormality, Inflammation	Altered Intercellular Communication	Computerized tomography (CT) of the hip and pelvis was then obtained, which was negative for boney abnormality but revealed a 5-cm ischiorectal abscess with inflammation of the adjacent gluteus muscle.	20825909
Inflammation, Impaired	Altered Intercellular Communication	In addition, we showed that telmisartan can reduce EPI-induced radical species, antagonize the inflammation, and reverse the early myocardial impairment.	20826257
Inflammation, Hyperviscosity, Myocardial dysfunction, Fibrinogen in blood above reference range	Altered Intercellular Communication	These findings support roles of inflammation, procoagulation, and hyperviscosity underlying hyperfibrinogenemia in the pathogenesis of incipient myocardial dysfunction.	20826256
Communicable Diseases, Disorder characterized by fever, Meningitis	Altered Intercellular Communication	All were admitted to hospital for febrile syndrome with abrupt clinical deterioration and suspected systemic infection without clear laboratory signs of meningeal inflammation.	20827778
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Alcohol consumption and markers of inflammation in women with preclinical rheumatoid arthritis.	20827783
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To examine the association between alcohol consumption and markers of inflammation in preclinical rheumatoid arthritis (RA).	20827783
Refractory anemias, Inflammation	Altered Intercellular Communication	These results demonstrate an association between alcohol consumption and markers of inflammation, including IL-6 and sTNFRII, in RA patients, prior to the occurrence of symptoms.	20827783
Acute Lung Injury, Inflammation	Altered Intercellular Communication	Endothelial microparticles induce inflammation in acute lung injury.	20828748
Diastolic dysfunction, Inflammation	Altered Intercellular Communication	Prolonged atrial electromechanical delay is due to provoked low-grade inflammation as well as LA enlargement and early LV diastolic dysfunction in obese subjects.	20829801
Asthma, Aspirin-Induced, Pneumonitis, Anguilla island	Altered Intercellular Communication	Aspirin-intolerant asthma (AIA), as a clinical syndrome caused by aspirin, is characterized by lung inflammation and reversible bronchoconstriction.	20831471
Aggressive behavior, Stomach Carcinoma	Altered Intercellular Communication	The significance of the Glasgow prognostic score (GPS), an inflammation-based prognostic score, as an indicator of aggressiveness in gastric carcinoma has not been investigated fully.	20832047
Stomach Carcinoma	Altered Intercellular Communication	The preoperative measurement of an inflammation-based prognostic score can demonstrate a strict stratification for the prognosis of patients with gastric carcinoma.	20832047
APP gene, Vascular Diseases, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Abdominal aortic aneurysm (AAA) is a complex vascular disease characterized by matrix degradation and inflammation and is a major cause of mortality in older men.	20833395
Inflammation, Fibrosis Assessment, Cardiac Arrhythmia, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation, oxidative injury, altered myocyte metabolism, extracellular matrix remodeling and fibrosis initiate and perpetuate cardiac arrhythmias, especially atrial fibrillation.	20833483
deficiency aspects, Inflammation, Fibrosis Assessment, Myocardial, Cardiac Arrhythmia	Altered Intercellular Communication	Hence, it is likely that leukocyte and/or myocardial deficiency of EPA and DHA and consequent reduced formation of lipoxins, resolvins, protectins and maresins enhance inflammation and MPO activity that leads to myocardial damage and fibrosis and initiation and progression of cardiac arrhythmias.	20833483
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation plays a role in the genesis and perpetuation of atrial fibrillation (AF).	20833691
Lepromatous, Peptic Ulcer, Gastrointestinal inflammation	Altered Intercellular Communication	These immunological results are consistent with previous histopathological studies illustrating a more severe gastrointestinal inflammation in lepromatous patients; importantly, a response to the 35 kDa antigen is recognized as a marker for the development of ulcerative disease.	20835617
Inflammation, Fibrosis Assessment, Aortic Aneurysm, Abdominal, Sigmoid colon, Inferior vena cava structure	Altered Intercellular Communication	Conventional open repair of inflammatory abdominal aortic aneurysms (IAAA) remains challenging through the presence of extensive peri-aortic inflammation and fibrosis which makes dissection and vascular control difficult with a risk of inadvertent injury to adjacent visceral structures such as the ureters, duodenum, inferior vena cava, left renal vein and sigmoid colon.	20835894
Inflammation, Fibrosis Assessment, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	IAAAs and the associated peri-aortic inflammation and fibrosis can be successfully treated using endovascular abdominal aortic aneurysm repair with concurrent ureteric stenting.	20835894
Inflammation	Altered Intercellular Communication	These results suggest that regular exercise is an important nonpharmacological strategy to the improvement in inflammation in CAD patients.	20835904
Inflammation	Altered Intercellular Communication	Additionally, 27-OHC caused glutathione depletion, ROS generation, inflammation and apoptotic-mediated cell death.	20836858
Inflammation, Diabetic Foot	Altered Intercellular Communication	It is very suggestive that diabetic foot is characterized by a pronounced inflammatory reaction and the pathogenic significance of this inflammation has received little attention.	20836881
Inflammation, Chronic disease, Obesity	Altered Intercellular Communication	Increased childhood obesity and low-grade inflammation may contribute to later life chronic disease risk.	20837281
Inflammation, Parotid Diseases, Malignant Neoplasms	Altered Intercellular Communication	Various parotid gland diseases are seen clinically, including inflammation, sialolithiasis, and benign and malignant tumors.	20837345
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Intestinal inflammation continued and impaired his quality of life; he was diagnosed with IBD of an undetermined type (IBD-U).	20837584
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Because the use of anti-inflammatory drugs in general is a marker for underlying inflammatory disorders, inflammation may be the common cause for the use of anti-inflammatory drugs and chronic AF.	20837831
Palmar-plantar erythrodysesthesia syndrome, Leukopenia, Abdominal Pain, Inflammatory disease of mucous membrane, Fatigue	Altered Intercellular Communication	Grade 3 adverse events included abdominal pain, mucosal inflammation, fatigue, neutropenia, and hand-foot syndrome.	20837944
Shock, Traumatic	Altered Intercellular Communication	These findings suggest that hormonal differences play a role in the gender-based outcome disparities after traumatic shock.	20838123
Diffuse Axonal Injury, Inflammation	Altered Intercellular Communication	The extent of paranodal axoglial (neurofascin-155(+)/Caspr1(+)) disruption correlated with local microglial inflammation and axonal injury (expression of nonphosphorylated neurofilaments) in MS NAWM.	20838243
Inflammation, Experimental Autoimmune Encephalomyelitis	Altered Intercellular Communication	Disruption of the axoglial unit in adjuvant-immunized animals was reversible and coincided with the resolution of microglial inflammation; paranodal damage and microglial inflammation persisted in chronic EAE.	20838243
Diffuse Axonal Injury, Inflammation	Altered Intercellular Communication	These data indicate that, in MS NAWM, permanent disruption to axoglial domains in an environment of microglial inflammation is an early indicator of axonal injury that likely affects nerve conduction and may contribute to physiologic dysfunction.	20838243
Celiac Disease, Inflammatory disease of mucous membrane, Immune-mediated, Villous atrophy	Altered Intercellular Communication	Celiac disease is an immune-mediated enteropathy characterized by mucosal inflammation and villous atrophy of the small bowel upon exposure to ingested gluten.	20839163
vascular inflammations	Altered Intercellular Communication	In addition, oxidized LDL and high-sensitivity C-reactive protein were determined as markers of oxidative stress and vascular inflammation.	20840194
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Transforming growth factor b-receptor II protein expression in benign prostatic hyperplasia is associated with prostate volume and inflammation.	20840324
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Inflammatory bowel disease (IBD) is associated with imbalances of the local intestinal immune responses, with dysregulated CD4(+) T cells contributing to the chronic inflammation.	20840654
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation contributes to atherosclerosis progression and influences both arginase and nitric oxide synthase expression.	20842428
TNF protein, human, Inflammation, Tumor necrosis	Altered Intercellular Communication	The markers of inflammation interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-a) were also assessed.	20842428
HD Term Type	Altered Intercellular Communication	HD could be considered as an inflammatory condition.	20842428
Inflammation, Carcinogenesis, Malignant neoplasm of endometrium, Obesity	Altered Intercellular Communication	We provided epidemiological evidence that chronic inflammation might mediate the association between obesity and endometrial cancer and that endometrial carcinogenesis could be promoted by an inflammatory milieu.	20843938
Inflammation, Aortic Aneurysm, Abdominal, Diabetes Mellitus	Altered Intercellular Communication	The influence of diabetes on degree of abdominal aortic aneurysm tissue inflammation.	20843966
Nephritis	Altered Intercellular Communication	Expression of the chemokine receptor CCR6 in human renal inflammation.	20844183
Nephritis	Altered Intercellular Communication	tertiary lymphoid organs, develop in the tubulointerstitium during chronic renal inflammation.	20844183
Nephritis	Altered Intercellular Communication	CCR6 and the corresponding ligand CCL20 might therefore be involved in the recruitment of T and B cells to organized nodular infiltrates in chronic renal inflammation.	20844183
Rupture, Inflammation	Altered Intercellular Communication	Rupture of HO-1(-/-) macrophages in vivo and release of nonmetabolized heme probably caused tissue inflammation.	20844238
Inflammation, High-Frequency Microsatellite Instability	Altered Intercellular Communication	Unlike microsatellite instability-high (MSI-H) in which hypermethylation of hMLH1 occurs followed by multiple susceptible gene mutations, EMAST may be associated with inflammation and subsequent relaxation of MMR function with the biological consequences not known.	20844976
Myocardial immune cell infiltration, Inflammation	Altered Intercellular Communication	The etiology and consequences of EMAST are under investigation, but its association with immune cell infiltration suggests that inflammation may play a role for its development.	20844976
Communicable Diseases, Stenosis, Epididymo-orchitis, Urethritis, Sepsis due to urinary tract infection	Altered Intercellular Communication	The leading etiology of the stricture was urethral inflammation (76.4%) with the commonest complication being infection: wound infection in 9.1%, urosepsis in 3.6%, and epididymo-orchitis in 1.8% of the subjects.	20845294
Granulomatous inflammation, Caseous necrosis	Altered Intercellular Communication	A transbronchial lung biopsy was performed and the histopathologic examination of the specimen from this lesion revealed granulomatous inflammation without caseous necrosis or acid-fast bacilli.	20845686
Pulmonary Infiltrate, Inflammation, Tuberculosis, Pulmonary	Altered Intercellular Communication	We believe that these lesions were pulmonary tuberculomas and transient intra-pulmonary infiltration due to non-specific inflammation, caused secondarily by an excessive immune response, as in paradoxical worsening.	20845686
Inflammation, Disease remission, Atherosclerosis, Calcified (qualifier), Calcinosis	Altered Intercellular Communication	Calcific AS, as an active disease process, is characterized by lipid accumulation, inflammation and calcification that mimic atherosclerosis.	20845892
Inflammation	Altered Intercellular Communication	A total of 23 selected patients with post-surgical neuropathies received nerve biopsies, of which 21 demonstrated increased inflammation.	20846945
Pain Distress Question, Inflammation, Ischemia, Neuropathy, Neurologic Symptoms, Weakness, Inflammatory neuropathy	Altered Intercellular Communication	(i) not all post-surgical neuropathies are mechanical, and inflammatory mechanisms can be causative, presenting as pain and weakness in a focal, multifocal or diffuse pattern; (ii) these inflammatory neuropathies may be recognized by their spatio-temporal separation from the site and time of surgery and by the characteristic magnetic resonance imaging features; (iii) occasionally post-surgical inflammatory and mechanical neuropathies are difficult to distinguish and nerve biopsy may be required to demonstrate an inflammatory mechanism, which in our cohort often, but not exclusively, exhibited pathological features of microvasculitis and ischaemia; and (iv) recognizing the role of inflammation in these patients' neuropathy led to rational immunotherapy, which may have resulted in the subsequent improvement of neurological symptoms and impairments.	20846945
Inflammation, Data types - Address	Altered Intercellular Communication	Specifically, we analyzed reduced inflammation and improved metabolic profile as a potential medium through which the MeDi reduced the risk of AD.	20847399
Chronic disease	Altered Intercellular Communication	The causes of growth disorder include hormonal irregularities, chronic disease, complications during pregnancy or genetic conditions.	20847595
Inflammation, Hepatobiliary Neoplasm, Biliary Tract Hemorrhage, Cholelithiasis, Traumatic injury, Vascular anomaly	Altered Intercellular Communication	The causes of hemobilia include trauma, gallstone disease, vascular malformation, inflammation, and biliary or hepatic tumors.	20847612
Keratitis	Altered Intercellular Communication	Role of human herpes virus 6 in corneal inflammation alone or with human herpesviruses.	20847652
Keratitis	Altered Intercellular Communication	: In 22 patients with corneal inflammation, HHV-6 was positive in 14 of 22 patients and HSV-1 was found in 9 of those patients.	20847652
Keratitis	Altered Intercellular Communication	These data indicated that the association of HHV-6 with disease was more frequent than with other herpesviruses and that HHV-6 may be another sole causative agent for corneal inflammation.	20847652
Inflammation, Disorders of Porphyrin Metabolism	Altered Intercellular Communication	This case highlights the usefulness of tissue biopsy in porphyria when one is uncertain as to whether a necrotizing process is driven by inflammation or phototoxic damage.	20847674
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome is marked by perturbed glucocorticoid (GC) signaling, systemic inflammation, and altered immune status.	20847733
Gastrointestinal inflammation	Altered Intercellular Communication	Glycogen synthase kinase 3-b: a master regulator of toll-like receptor-mediated chronic intestinal inflammation.	20848477
Gastrointestinal inflammation	Altered Intercellular Communication	Intestinal inflammation was evaluated by histologic analysis and cytokine secretion of mesenteric lymph node cells (MLC).	20848477
Inflammatory Bowel Diseases	Altered Intercellular Communication	The expression differences between ileal CD, colonic CD, and previously identified UC-associated miRNAs support the likelihood that miRNAs influence differing inflammation-related gene expression in each inflammatory bowel disease (IBD) subtype and may form the basis for future diagnostic tests and therapeutic targets for IBD.	20848482
Inflammation, Liver diseases	Altered Intercellular Communication	IL-17 as a new cytokine probably play a multiple role as immune factor and inflammation element in the progression of the chronic hepatitis B disease.	20848848
Sleep abnormalities, Parkinsonian Disorders	Altered Intercellular Communication	Dopamine is an important neurotransmitter in the regulation of the sleep-wake cycle, and parkinsonian patients suffer from prominent sleep abnormalities.	20849470
Communicable Diseases, Helicobacter pylori, Gastritis, Obesity	Altered Intercellular Communication	Infection with Helicobacter pylori, which induces persistent and uncontrolled gastric inflammation leading to decreased appetite, might be protective against obesity.	20850344
Uremia, Communicable Diseases, Inflammation, Anorexia	Altered Intercellular Communication	Hypothesis of the present study was that infection with H pylori in subjects with uremia might cause inflammation, diminished appetite, anorexia, and decreased IDWG.	20850344
Malnutrition	Altered Intercellular Communication	Malnutrition inflammation score, spKt/V, and normalized protein equivalent of total nitrogen appearance were determined.	20850344
Inflammation	Altered Intercellular Communication	Isolated granulomatous inflammation of the appendix is extremely rare, and its etiology is still unknown.	20850613
Inflammation, Pyelonephritis	Altered Intercellular Communication	Voiding cystourethrogram was investigated after acute pyelonephritis was confirmed by renal scan and acute inflammation subsided, about 2 to 4 weeks later.	20850815
Granulomatous inflammation	Altered Intercellular Communication	Two patients' lesions were biopsied, revealing granulomatous inflammation.	20851656
Intraocular inflammation	Altered Intercellular Communication	Although intraocular inflammation seemed to be successfully controlled, the number of giant-cell deposits on the posterior surface of the posterior capsule was gradually increased with the development of posterior capsular opacification in 5 and 9 months, respectively, and neodymium-doped yttrium-aluminum-garnet (Nd:YAG) laser capsulotomy was required.	20854015
Inflammation, Atherosclerosis	Altered Intercellular Communication	The measurements included markers of systemic inflammation, subclinical atherosclerosis, left ventricular mass index, composite and individual cardiovascular end points, and all-cause mortality.	20854960
Inflammation, Atherosclerosis	Altered Intercellular Communication	The MS plus MA group showed a consistently stronger association with the markers of systemic inflammation, subclinical atherosclerosis, and most clinical end points compared to the other study groups.	20854960
Renal Insufficiency, Inflammation, Heart failure, Muscle Cells	Altered Intercellular Communication	Higher levels were associated with features of worse heart failure and biomarkers of neurohormonal activation, inflammation, myocyte injury, and renal dysfunction.	20855664
Inflammation, Fibrosis Assessment, Retractile Mesenteritis	Altered Intercellular Communication	Sclerosing mesenteritis is a rare disease of unknown etiology that is characterized by self-limited, nonspecific inflammation and fibrosis of the mesenteric adipose tissue.	20855700
Neonatal stroke, White matter	Altered Intercellular Communication	Melatonin promotes myelination by decreasing white matter inflammation after neonatal stroke.	20856166
Infarction, Inflammation, Cerebrovascular accident	Altered Intercellular Communication	These results suggest that melatonin is not able to reduce cortical infarct volume in a neonatal stroke model but strongly reduces inflammation and promotes subsequent myelination in the white matter.	20856166
Inflammation, Helicobacter pylori	Altered Intercellular Communication	Relationship of the intensity of Helicobacter pylori and severity of inflammation with beta-2 microglobulin levels in serum according to the updated Sydney System.	20856179
Inflammation	Altered Intercellular Communication	We investigate the usability of beta-2 microglobulin as a simple marker that may reflect the severity of inflammation and intensity of HP in gastric mucosa.	20856179
Stomatitis	Altered Intercellular Communication	No statistically significant result was found between serum beta-2 microglobulin levels and the intensity of HP and the severity of inflammation of gastric mucosa.	20856179
Inflammation	Altered Intercellular Communication	We suggest that the serum beta-2 microglobulin level cannot be used as a simple marker of HP intensity and severity of inflammation in gastric endoscopic biopsies.	20856179
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation and structural alterations (ie, tissue remodeling) throughout the conducting airways, parenchyma, and pulmonary vasculature.	20856827
Inflammation, Coronary heart disease	Altered Intercellular Communication	Heart rate variability and biomarkers of systemic inflammation in patients with stable coronary heart disease: findings from the Heart and Soul Study.	20857123
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Reduced cardiac autonomic control is associated with increased systemic inflammation in patients with stable CHD.	20857123
Inflammation, Chronic pain	Altered Intercellular Communication	MMP-9 and -13 mRNA levels were significantly elevated in patients with chronic pain, presumably as a consequence of neovascularization and chronic inflammation.	20857147
Inflammation, Chronic Obstructive Airway Disease, Allergic	Altered Intercellular Communication	The differences of eosinophil- and neutrophil-related inflammation in elderly allergic and non-allergic chronic obstructive pulmonary disease.	20858153
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a common disease in the elderly population and is characterized by airway inflammation.	20858153
allergic inflammation	Altered Intercellular Communication	Whether it is a progressive condition resulting from allergic inflammation or a distinct condition involving a pathogen-induced reaction remains unclear.	20858153
ARCN1 gene, allergic inflammation	Altered Intercellular Communication	To determine the role of allergic inflammation in the pathogenesis of elderly COPD.	20858153
Blindness, Orbital Pseudotumor	Altered Intercellular Communication	Idiopathic orbital inflammation leading to unilateral blindness over a 2-day presentation in a child.	20859233
Orbital Pseudotumor	Altered Intercellular Communication	Orbital imaging revealed enlarged extraocular muscles, and biopsy confirmed idiopathic orbital inflammation.	20859233
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	The hallmark of cystic fibrosis (CF) is chronic lung inflammation.	20859300
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Lifestyle habits, vascular function and inflammation are components in the development of cardiovascular disease (CVD).	20859301
Inflammation	Altered Intercellular Communication	In contrast, chronic GvHD patients who did not develop acute GvHD earlier displayed significantly increased Treg cell numbers at the timepoint of chronic inflammation.	20859740
Fasciitis, Heel, Bursitis, Bone structure of calcaneum, Compression injury of nerve	Altered Intercellular Communication	According to the classification:67 heels with plantar fasciitis type, 61 heels with calcaneal bursitis type, 36 heels with plantar fat pad inflammation-based type, 6 heels with calcaneus high pressure-type, 21 heels with nerve compression type, 75 heels with mixed type.	20860141
Inflammation	Altered Intercellular Communication	Inflammation and immune response in acute aortic dissection.	20860543
Inflammation, Periodontitis, Coronary heart disease, Chronic disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Coronary heart disease (CHD) and chronic periodontitis (CP) both are multifactorial chronic diseases and related to inflammation.	20860764
Inflammation, Dental Plaque, Dental caries	Altered Intercellular Communication	Children with severe caries (n = 39) had more dental plaque and gingival inflammation than caries-free children (n = 41).	20861633
Weight decreased, Nephritis	Altered Intercellular Communication	Surgically induced weight loss contributed to a decrease in blood pressure and markers of renal inflammation.	20862711
Inflammation, Blood coagulation	Altered Intercellular Communication	l-Carnitine supplement reduces serum CRP, a marker of systemic inflammation, and plasma fibrinogen, an inflammation-related coagulation factor, in hemodialysis patients.	20863217
Inflammation	Altered Intercellular Communication	We speculate that this lesion is due to inflammation of the biceps tendon resulting in increased biceps-humeral head contact pressure.	20863719
Acute Coronary Syndrome, Cardiovascular system	Altered Intercellular Communication	(FRANCIS [Fewer Recurrent Acute Coronary Events With Near-Term Cardiovascular Inflammation Suppression]-ACS Trial: A Study of the Safety and Efficacy of A 002 in Subjects With Acute Coronary Syndromes; NCT00743925).	20863951
Inflammation	Altered Intercellular Communication	IL-17A plays a role in small airway subepithelial inflammation, whereas IL-17F appears to play a more prominent role within lymphoid follicles.	20864612
Airway structure	Altered Intercellular Communication	The measurement of the exhaled nitric oxide fraction (FE(NO)) is proposed as a useful marker of airway inflammation.	20864792
Steatohepatitis, Non-alcoholic Fatty Liver Disease, Hypopituitarism, hormone deficiency	Altered Intercellular Communication	Severe growth hormone deficiency in hypopituitarism was associated with the severe degree of hepatic steatosis in NAFLD.	20865648
Communicable Diseases, Inflammation, Helminths	Altered Intercellular Communication	Infection with helminths is associated with shifts in host immunity, including increased production of immunoglobulin E (IgE) and reduced inflammation.	20865759
Inflammation, Fat necrosis, Pancreatitis Necrotizing	Altered Intercellular Communication	An incisional biopsy revealed lobular inflammation of subcutaneous fat, focal fat necrosis with saponification/ghost cells and scattered foreign-body type giant cells consistent with pancreatic fat necrosis/pancreatic panniculitis.	20865849
Inflammation, Erythema, Phrynoderma, Alopecia	Altered Intercellular Communication	Clinical effects, in the sense of stabilization with cessation of the inflammation (erythema, follicular hyperkeratosis, loss of anagen hair), were achieved in all patients but three.	20868410
Inflammation, Pulmonary Hypertension	Altered Intercellular Communication	Fractalkine (FKN), a unique chemokine associated with pulmonary hypertension, may be involved in the acute stress response that regulates inflammation after cardiopulmonary bypass (CPB) surgery.	20869263
Osteitis, Ear Inflammation	Altered Intercellular Communication	NOE may develop in patients with benign otitis media and externa, and must be considered in all patients with temporal bone inflammation, especially those with risk factors and those who fail to improve with more conservative measures.	20869559
RECIL MR	Altered Intercellular Communication	Aortic wall inflammation using USPIO-enhanced MR imaging is feasible.	20869889
Myopia, Ulcerative Colitis	Altered Intercellular Communication	The patient had not disclosed her history of a total colectomy for recurrent ulcerative colitis and developed bilateral stromal inflammation and corneal melting along the flap edge with ulceration within 3 days of uneventful bilateral LASIK for myopia.	20870127
Inflammation, Neoplasms	Altered Intercellular Communication	The most common findings were angiectasias (61.5%), inflammation (7.5%), and neoplasia (6.8%).	20870226
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Our results add weight to concerns that pollution may be an important trigger of inflammation and autoimmunity.	20870568
ARCN1 gene, Inflammation, Demographics Domain, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus, Cerebrovascular accident, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Comorbidities associated with systemic inflammation including cardiovascular disease (CVD), stroke and diabetes mellitus (DM) are common among individuals with chronic obstructive pulmonary disease (COPD).	20871122
Inflammation	Altered Intercellular Communication	The adipocyte-derived cytokine leptin was implicated to link inflammation and metabolic alterations.	20871818
Inflammation, Critical Illness, Hyperglycemia	Altered Intercellular Communication	We investigated the potential role of leptin components in critically ill patients, because systemic inflammation, insulin resistance, and hyperglycemia are common features of critical illness.	20871818
Communicable Diseases, Inflammation, Fever, CTCAE	Altered Intercellular Communication	We conclude that fever, even up to the seventh postoperative day, is not substantially helpful to distinguish infection from general inflammation in clean orthopaedic surgery.	20871993
Acute Coronary Syndrome, Hemorrhage, Inflammation	Altered Intercellular Communication	Bleeding events are associated with an increase in markers of inflammation in acute coronary syndromes: an ACUITY trial substudy.	20872045
Inflammation, MS gene	Altered Intercellular Communication	Glial activation in the setting of central nervous system inflammation is a key feature of the multiple sclerosis (MS) pathology.	20872081
Inflammation	Altered Intercellular Communication	Focal increases in [(11)C]PBR28 binding corresponded to areas of active inflammation as evidenced by significantly greater binding in regions of gadolinium contrast enhancement compared to contralateral normal-appearing white matter (p = 0.0039).	20872081
Granuloma, Inflammation	Altered Intercellular Communication	Histological examination showed non-caseation granulomas in mesenteric lymph nodes and transmural inflammation in the cecum.	20872335
Inflammation, Malnutrition, Impaired cognition, Cardiovascular Diseases, Depression, CTCAE	Altered Intercellular Communication	In these patients, the early identification of the specific clinical problems that may cause many adverse effects for the dialysis treatment population becomes a relevant factor: e.g., cardiovascular diseases, malnutrition, inflammation, depression and cognitive disturbances.	20872375
Cessation of life, Inflammation, Coronary heart disease	Altered Intercellular Communication	Chronic inflammation and oxidative stress increase with advancing age and appear to be involved in the pathogenesis of coronary heart disease, the leading cause of death worldwide.	20874680
Inflammation, Intradermal Route of Drug Administration, Overweight	Altered Intercellular Communication	The lack of association between overweight and ID in the present study could be due to the fact that the excess of body fat of the women might not be critical to induce chronic inflammation related to reduced Fe absorption.	20875192
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Altered glutamatergic synaptic transmission is among the key events defining the course of Alzheimer's disease (AD).	20875805
glycation, Inflammation	Altered Intercellular Communication	Blockade of PKC-beta protects HUVEC from advanced glycation end products induced inflammation.	20875828
Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The lack of utility of circulating biomarkers of inflammation and endothelial dysfunction for type 2 diabetes risk prediction among postmenopausal women: the Women's Health Initiative Observational Study.	20876407
Endothelial dysfunction, Inflammation, Demographics Domain, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Recent studies have linked plasma markers of inflammation and endothelial dysfunction to type 2 diabetes mellitus (DM) development.	20876407
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	However, serum Fe markers are influenced by inflammation or malignancy and may not accurately reflect the amount of body Fe.	20876673
Inflammation, Endotoxemia, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Circulating endotoxemia: a novel factor in systemic inflammation and cardiovascular disease in chronic kidney disease.	20876680
Inflammation, Malnutrition, Endotoxemia, Injury of cardiac valve	Altered Intercellular Communication	Resultant endotoxemia is associated with systemic inflammation, markers of malnutrition, cardiac injury, and reduced survival.	20876680
Acute Lung Injury, Pneumonitis, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	Acute lung injury and acute respiratory distress syndrome (ALI/ARDS) are severe forms of bilateral lung inflammation with poor clinical outcomes.	20877166
glycation, Inflammation	Altered Intercellular Communication	Soluble receptor for advanced glycation endproducts (sRAGE) plays a key regulatory role during the acute phase of inflammation, and baseline plasma levels of sRAGE were recently found to be associated with severity of ALI/ARDS.	20877166
Inflammation, Ischemic stroke, Reperfusion Injury	Altered Intercellular Communication	Inflammatory cytokines are involved in the systemic inflammation, which precedes an ischaemic stroke (IS), and also participate into brain ischaemia-reperfusion injury.	20880001
Airway structure	Altered Intercellular Communication	Lung function was followed as FEV(1) and airway inflammation as fraction of exhaled nitric oxide (F(E) NO).	20880055
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	A randomised placebo-controlled double-blind trial to evaluate lipid-lowering pharmacotherapy on proteolysis and inflammation in abdominal aortic aneurysms.	20880729
ARCN1 gene, Chronic Obstructive Airway Disease, exacerbation acute, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by airway inflammation and is associated with acute exacerbations.	20881376
ARCN1 gene, Exacerbation, Airway structure	Altered Intercellular Communication	Erythromycin treatment in COPD patients can reduce airway inflammation and decrease exacerbations and may therefore be useful in the management of COPD.	20881376
Corneal edema, Hyperemia	Altered Intercellular Communication	On days 7, 14, 21 and 28, the frequency of inflammation-related signs (corneal edema, conjunctival hyperemia, anterior chamber or Tyndall reaction) as well as best-corrected visual acuity (BCVA) were measured.	20881443
Pseudoexfoliation	Altered Intercellular Communication	On day 21, pseudoexfoliation was associated with the presence of any inflammation-related sign (OR = 4.5; 95% CI: 1.2-16.0; p = 0.022).	20881443
Inflammation, Pathology	Altered Intercellular Communication	The pathologies promoting hospitalization could influence this derangement through inflammation but this hypothesis should be investigated.	20882095
Inflammation, Radiation Damage	Altered Intercellular Communication	Our hypothesis was that pretreatment inflammation in the lung makes pulmonary tissue more susceptible to radiation damage.	20884128
Inflammation	Altered Intercellular Communication	The relationship between pretreatment [(18)F]fluorodeoxyglucose ([(18)F]FDG) uptake in the lungs (as a surrogate for inflammation) and the delivered radiation dose and radiation-induced lung toxicity (RILT) was investigated.	20884128
Inflammation, Heart Arrest, Induced	Altered Intercellular Communication	On-pump coronary surgery with and without cardioplegic arrest: comparison of inflammation, myocardial, cerebral and renal injury and early and late health outcome in a single-centre randomised controlled trial.	20884221
Inflammation, Thrombosis, Ventricular Arrhythmia, CTCAE 5.0, Electrocardiogram: myocardial infarction (finding), ST Elevation Myocardial Infarction by ECG Finding, Shock, Dental Plaque	Altered Intercellular Communication	Statins favourably affect platelet adhesion, thrombosis, endothelial function, inflammation, plaque stability, and ventricular arrhythmia, which may potentially improve outcome after percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI) and shock.	20884413
Inflammation	Altered Intercellular Communication	PIs induced senescence markers, prelamin A accumulation, oxidative stress, and inflammation in HCAECs.	20884875
Granulomatous inflammation	Altered Intercellular Communication	Although hair cortex comedo was thought originally to be a variant of dilated pore of Winer, we believe that these distinctive lesions, which are characterized histopathologically by a uniformly sized vertically oriented dermal plug of laminated corneocytes with entrapped melanin and surrounding granulomatous inflammation, are likely derived from matrical or supramatrical cells (or both).	20885284
Inflammation	Altered Intercellular Communication	Confocal microscopy can detect subtle corneal changes in patients with CD, which may be signs of subclinical inflammation.	20885311
vascular inflammations	Altered Intercellular Communication	High blood pressure (BP) levels in African Americans elicit vascular inflammation resulting in vascular remodeling.	20885987
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	We therefore aimed to investigate the relationship between prolactin, acute stress and inflammation in patients with myocardial infarction.	20886416
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Microfibrillar collagen hemostat-induced necrotizing granulomatous inflammation developing after craniotomy: a pediatric case series.	20887115
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Airway inflammation is a known pathological feature of chronic obstructive pulmonary disease (COPD).	20887348
vascular inflammations	Altered Intercellular Communication	Deciphering STAT3 signaling in the heart: plasticity and vascular inflammation.	20887622
Inflammation, Heart failure, Hypertrophy	Altered Intercellular Communication	In this case, inflammation, aging, hypertrophy, and heart failure provide new environments that certainly impact on the functioning of STAT3 and on the gene profile linked to its activation.	20887622
Inflammation	Altered Intercellular Communication	Our data suggests that there are indeed age-dependent characteristics of culprit coronary plaque inflammation.	20888054
Inflammation, Dental Plaque	Altered Intercellular Communication	In particular, older subjects demonstrate a plaque phenotype with higher amounts of inflammation and lower levels of Treg cells.	20888054
Inflammation, Dental Plaque	Altered Intercellular Communication	Despite lower levels of inflammation, younger subjects also had fatal outcomes, indicating that alternative factors may be more important in plaque stability.	20888054
Pituitary Adenoma	Altered Intercellular Communication	Pituitary adenomas should be considered in the differential diagnosis of patients presenting with spontaneous CSF rhinorrhea with abnormal sellar image, and these patients should undergo a thorough hormonal evaluation.	20888068
Communicable Diseases, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Cystic fibrosis (CF) is characterised by impaired mucociliary clearance (MCC), chronic inflammation and infection, and progressively deteriorating lung function.	20888307
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The chitinase-like protein YKL-40 is a serum biomarker in diseases with fibrosis, inflammation and tissue remodelling.	20888745
Inflammation, Aortic Stiffness, Cerebrovascular accident	Altered Intercellular Communication	Our findings show that both aortic stiffness and wave reflection are related to the degree of systemic inflammation in stroke subjects, suggesting that circulating inflammation mediators can influence the stiffness of vessels distant to those involved in the disease process itself.	20889155
Inflammation	Altered Intercellular Communication	Because immunosuppressive agents are known to abate inflammation, we hypothesized the superior outcome of lower extremity bypass in renal transplant recipients compared with the hemodialysis population.	20889298
ARCN1 gene, Rhinovirus infection, Airway structure	Altered Intercellular Communication	After rhinovirus infection subjects with COPD developed lower respiratory symptoms, airflow obstruction, and systemic and airway inflammation that were greater and more prolonged compared with the control group.	20889904
Inflammation, Exacerbation	Altered Intercellular Communication	Impaired IFN production and neutrophilic inflammation may be important mechanisms in virus-induced COPD exacerbations.	20889904
Sepsis, Inflammation	Altered Intercellular Communication	Excessive inflammation is closely related to severity and outcome of sepsis.	20890200
ARCN1 gene, Inflammation, Pulmonary Hypertension	Altered Intercellular Communication	However, little information exists regarding the potential role of systemic inflammation in pulmonary hypertension of COPD.	20890431
Hepatitis	Altered Intercellular Communication	The platelet proteome was found highly responsive to each physiological stage of liver inflammation or pathogenesis.	20919743
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide (NO) is used as a surrogate marker to monitor eosinophilic airway inflammation, assist in diagnosis, and support treatment decisions for asthma patients.	20920124
Inflammation, Kidney Failure, Alport Syndrome, Hereditary	Altered Intercellular Communication	Alport syndrome (AS) is a rare inherited disorder characterized by an inflammation of the kidneys and damage to the glomerular capillaries, ultimately leading to renal failure at an early age.	20920374
Inflammation, Metabolic Syndrome X, Diabetes Mellitus	Altered Intercellular Communication	Relation of plasma fatty acid binding proteins 4 and 5 with the metabolic syndrome, inflammation and coronary calcium in patients with type-2 diabetes mellitus.	20920650
Inflammation, Disease, Atherosclerosis	Altered Intercellular Communication	Fatty acid-binding proteins (FABPs) 4 and 5 play coordinated roles in rodent models of inflammation, insulin resistance, and atherosclerosis, but little is known of their role in human disease.	20920650
Inflammation, Atherosclerosis	Altered Intercellular Communication	In correlation analysis, markers of nutrition, inflammation and atherosclerosis correlated well with m-BIA parameters.	20921295
palladium, Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	FO defined by m-BIA is significantly correlated with markers of malnutrition, inflammation and atherosclerosis in PD patients.	20921295
vascular inflammations	Altered Intercellular Communication	Plasma pentraxin3 (PTX3), a marker of vascular inflammation, was also measured.	20922537
Inflammation, Corneal stromal edema	Altered Intercellular Communication	The diagnostic features that are useful in the recognition of this benign entity are the characteristic mixture of various architectural patterns, associated stromal edema and inflammation, hyaline sheath around tubules, eosinophilic colloidlike secretion within tubules, and lack of mitotic activity.	20923300
Inflammation, Malignant neoplasm of gallbladder	Altered Intercellular Communication	Conflicting results exist with regard to the prognostic significance of p21 and p53 expression, and the strong association of gallbladder cancer with chronic inflammation makes it only natural that COX2 negativity is rarely encountered, even in non-neoplastic biliary epithelia.	20924037
Inflammation, Colorectal Neoplasms	Altered Intercellular Communication	Flavonols, bioactive compounds found in plant-based foods and beverages, may inhibit colorectal neoplasms partly by attenuating inflammation.	20924374
Inflammation, Erythema	Altered Intercellular Communication	Given that her initial diagnosis was made with a sigmoidoscopy we scheduled a total colonoscopy showing marked inflammation, erythema and friability limited to the recto-sigmoid mucosa, like at the disease onset, and when we reached the cecum an erythematous area circumscribed to the appendiceal orifice was observed, with a mucosal aspect identical to the described for the recto-sigmoid mucosa.	20924432
Inflammation, Bacterial Infections	Altered Intercellular Communication	Presence of age-associated low-grade inflammation does not worsen the body response to bacterial infection in old male rats.	20924673
Inflammation	Altered Intercellular Communication	In the field of frailty, there is an underlying hypothesis that chronic low-grade inflammation contributes to bad outcomes in response to a stressor.	20924673
Communicable Diseases, Inflammation	Altered Intercellular Communication	The host response to an Escherichia coli infection was assessed in 24 month old male rats exhibiting a chronic low-grade inflammation and in non-inflamed control rats.	20924673
Inflammation, Weight decreased, Decreased Bone Tissue	Altered Intercellular Communication	The presence of chronic low-grade inflammation did not affect post-infection mortality, body weight loss and tissue mass decreases.	20924673
Inflammation, Bacterial Infections	Altered Intercellular Communication	Altogether, age-associated chronic low-grade inflammation in male rats did not worsen the body response to bacterial infection.	20924673
Inflammation	Altered Intercellular Communication	These results suggest that chronic low-grade inflammation is not an aggravating factor of the spiraling process leading to frailty.	20924673
Presenile dementia, Lewy Bodies, dendritic lamellar body, Hypoperfusion	Altered Intercellular Communication	Dementia with Lewy bodies (DLB) is often associated with occipital hypometabolism or hypoperfusion, as well as deficits in cholinergic neurotransmission.	20924800
ARCN1 gene, Airway structure, Chronic Obstructive Airway Disease, Asthma, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Chronic airway inflammation in asthma or chronic obstructive pulmonary disease (COPD) may be involved in the pathogenesis of type 2 diabetes; however, prospective data have been limited.	20926152
ARCN1 gene, Airway structure, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus	Altered Intercellular Communication	Asthma and COPD were individually and independently associated with an increased risk of type 2 diabetes in women, indicating that chronic airway inflammation may contribute to diabetes pathogenesis.	20926152
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	We examined components of the metabolic syndrome, insulin resistance, a marker of inflammation, and the presence of painful comorbidities as possible mediators of this association.	20926190
Inflammation, Chronic pain, Obesity	Altered Intercellular Communication	After adjustment for insulin resistance, inflammation, and pain-related comorbidities, central obesity predicted higher TPI scores (OR 1.55, 95% CI 1.04-2.33) and nearly doubled the risk of chronic pain (OR 1.70, 95% CI 1.05-2.75).	20926190
Pain Distress Question, Inflammation, Neuropathy, Metabolic Syndrome X, Degenerative polyarthritis, Obesity	Altered Intercellular Communication	Central obesity is the metabolic syndrome component showing the strongest independent association with pain, and the relationship is not explained by markers of insulin resistance or inflammation, nor by the presence of osteoarthritis or neuropathy.	20926190
Inflammation, Peripheral Arterial Diseases	Altered Intercellular Communication	Hypoxia-inducible factor 1 (HIF1) is a key regulator of angiogenesis and is involved in inflammation, which are two important features of the pathogenesis of peripheral artery disease (PAD).	20926496
Inflammation, Neurogenic Inflammation, Cerebral dysfunction, Virus Diseases, Hepatitis C	Altered Intercellular Communication	As the increase of choline, creatine and myo-inositol are usually interpreted to indicate glial activation and macrophage infiltration in chronic inflammation and slow virus infections of the brain the present data endorse the hypothesis, that HCV infection may induce neuroinflammation and brain dysfunction.	20926642
Airway structure, asthma chronic	Altered Intercellular Communication	The T cell-driven airway inflammation in chronic asthma is uninhibited and sustained.	20926789
Rheumatoid Arthritis, Inflammatory abnormality of the eye, Psoriasis, Uveitis	Altered Intercellular Communication	We evaluated efficacy by measuring the psoriasis area and severity index (PASI), the American College of Rheumatology 20% response (ACR20) for rheumatoid arthritis, or the number of responders for uveitis, as defined by either vision improvement or reduction in ocular inflammation or corticosteroid dose.	20926833
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Reciprocity of inflammation, oxidative stress and neovascularization is emerging as an important mechanism underlying numerous processes from tissue healing and remodelling to cancer progression.	20927103
Inflammation, Neoplasms, melanoma	Altered Intercellular Communication	Here we show that the end products of lipid oxidation, o-(2-carboxyethyl)pyrrole (CEP) and other related pyrroles, are generated during inflammation and wound healing and accumulate at high levels in ageing tissues in mice and in highly vascularized tumours in both murine and human melanoma.	20927103
Acromegaly, Cardiovascular Diseases, Malignant Neoplasms, Respiration Disorders	Altered Intercellular Communication	Acromegaly is characterized by chronic hypersecretion of growth hormone (GH) and is associated with increased mortality rate because of the potential complications such as cardiovascular disease, respiratory disease, or malignancy, which are probably caused by the long-term exposure of tissues to excess GH, for at least 10 years, before diagnosis and treatment.	20930439
Inflammation, Coronary Arteriosclerosis, Tissue injury	Altered Intercellular Communication	The complement system plays a major role in inflammation and tissue injury following myocardial ischemia and reperfusion (MI/R) injury.	20930931
Inflammation, Lymphohistiocytosis, Hemophagocytic, Systemic Vasculitis	Altered Intercellular Communication	After the inflammation and ANCA titers were resolved with steroid therapy for suspected microscopic polyangiitis, hemophagocytic syndrome developed.	20931273
Pharyngitis, Nasopharyngeal carcinoma	Altered Intercellular Communication	Methylation specific PCR revealed that 36.7% (11/30) of nasopharyngeal carcinoma tissues and all of the chronic nasopharyngeal inflammation samples were methylated.	20932276
Inflammation, Paronychia Inflammation	Altered Intercellular Communication	Retronychia is the phenomenon of ingrown nail resulting in inflammation of the proximal subungual fold and is a newly described entity.	20932446
Inflammation, Calcification of coronary artery	Altered Intercellular Communication	Inflammation, coronary artery calcification and cardiovascular events in incident renal transplant recipients.	20934074
Inflammation, "Alzheimers Disease", Cerebral Ischemia, Cerebrovascular accident	Altered Intercellular Communication	Triflusal reduces cerebral ischemia induced inflammation in a combined mouse model of Alzheimer's disease and stroke.	20934412
Infarction, Inflammation	Altered Intercellular Communication	Triflusal reduced inflammation surrounding the endothelin-induced infarct only.	20934412
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	Inflammation is involved in the pathogenesis of nonrheumatic aortic valve stenosis (AS).	20934563
Inflammation, Asthma	Altered Intercellular Communication	This pathway is involved in immune responses to inflammation, including asthma.	20934631
Intraocular inflammation	Altered Intercellular Communication	One case of intraocular inflammation occurred >6 months after removal of perfluoro-n-octane tamponade.	20934993
Inflammation, Carcinogenesis	Altered Intercellular Communication	Chronic inflammation may be important in prostate carcinogenesis.	20935064
Intraocular inflammation, Choroiditis, Retinal vascular occlusion, Uveitis	Altered Intercellular Communication	In QuantiFERON-positive patients with severe uveitis forms, such as serpiginous choroiditis and occlusive retinal vasculitis, (18)F-FDG-PET/CT is useful to identify lesions appropriate for biopsy and helps to establish the diagnosis and appropriate therapy for presumed tuberculosis-induced intraocular inflammation.	20935307
Cerebral Amyloid Angiopathy, Inflammation	Altered Intercellular Communication	Cerebral amyloid angiopathy related inflammation: three case reports and a review.	20935328
Cerebral Amyloid Angiopathy, Inflammation, Encephalopathy, CTCAE 5.0	Altered Intercellular Communication	Cerebral amyloid angiopathy related inflammation (CAA-I), previously described under various names, is a treatable encephalopathy usually occurring in older adults.	20935328
Inflammation, Epithelial metaplasia	Altered Intercellular Communication	Epithelial metaplasia and XG inflammation are often associated with GBC but do not appear to play a role in its pathogenesis through the p53 pathway.	20935395
Inflammation, Osteoporosis	Altered Intercellular Communication	While CRP, a systemic inflammation marker, is thought to be associated with osteoporosis, evidence supporting this claim has been limited.	20936400
Inflammation, Kyphosis deformity of spine	Altered Intercellular Communication	The SCH in AS might be caused by inflammation, and thoracolumbar hyperkyphosis results from AS might be associated with the development of SCH.	20936535
Airway structure, Asthma	Altered Intercellular Communication	Fractional exhaled nitric oxide (FeNO) has been proposed as a biomarker of airway inflammation for cohort studies of asthma.	20936992
Inflammation, Heartburn	Altered Intercellular Communication	There was a reduction in self-assessed symptoms of heartburn (P = 0.0005) and regurgitation (P < 0.0001), and inflammation and proliferation in the Barrett's mucosa.	20937048
Gastroesophageal reflux disease, Inflammation	Altered Intercellular Communication	High-dose esomeprazole achieved higher levels of gastric acid suppression and control of oesophageal acid reflux and symptoms, with significant decreases in inflammation and epithelial proliferation.	20937048
Inflammation, Neoplasm Metastasis, Congenital stenosis of esophagus	Altered Intercellular Communication	Secondary stenosis due to factors such as inflammation did not appear present, so congenital esophageal stenosis (CES) was diagnosed.	20938113
Inflammation, hepcidin, Anemia, Traumatic injury	Altered Intercellular Communication	Hepcidin in trauma: linking injury, inflammation, and anemia.	20938270
Inflammation, Wounds and Injuries, hepcidin	Altered Intercellular Communication	We sought to define the link between traumatic injury, hepcidin, and inflammation.	20938270
Inflammation, Obstruction, Pterygium Of Conjunctiva And Cornea, Astigmatism	Altered Intercellular Communication	Pterygium is a chronic fibrovascular overgrowth on the corneal surface and is often associated with inflammation, astigmatism and obstructed vision.	20938674
Cessation of life, Stomach Carcinoma	Altered Intercellular Communication	Gastric cancer (GC) is a second most common cause of cancer-related death and represents an inflammation-driven malignancy.	20938721
Inflammation, Dental Plaque, Atherosclerotic lesion	Altered Intercellular Communication	inflammation plays an essential role in the development and progression of atherosclerotic lesions and plaque disruption.	20939703
Communicable Diseases, Vesicovaginal Fistula, Inflammation	Altered Intercellular Communication	Considering possible infection and inflammation remaining, we decided to perform abdominal repair of the vesicovaginal fistula about three months after the operation.	20940528
Colitis	Altered Intercellular Communication	DSS mice also had smaller testes, lower FSH levels, increased systemic cytokines, and increased colonic inflammation by histology.	20940665
Inflammation, Acidemia, Hypercapnia	Altered Intercellular Communication	Laboratory findings revealed mild inflammation, mild acidemia, and hypercapnea with radiologic infiltrations in the right lung, and remarkable wheezes in both lungs were heard on auscultation.	20941521
Inflammation	Altered Intercellular Communication	Primary inflammation of an epiploic appendix of the ascending colon.	20941981
Inflammation, atherosclerotic	Altered Intercellular Communication	Inflammation plays a crucial role in the development and progression of atherosclerotic plaques.	20943047
Structure of suprasellar region, Sarcoidosis, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Open biopsy of the suprasellar mass showed non-caseating chronic granulomatous inflammation compatible with sarcoidosis.	20943117
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Mounting evidence has revealed that chronic inflammation can be an important initiating factor of PCa.	20943438
Inflammation, Pancreatic Intraductal Papillary Mucinous Neoplasm, Adenocarcinoma of pancreas	Altered Intercellular Communication	The role of inflammation in patients with intraductal mucinous neoplasm of the pancreas and in those with pancreatic adenocarcinoma.	20944173
Inflammation, Pancreatic Intraductal Papillary Mucinous Neoplasm	Altered Intercellular Communication	There are very few data regarding inflammation in patients with intraductal papillary mucinous neoplasms (IPMNs) of the pancreas.	20944173
Inflammation, Hypertension, CTCAE, Obesity, Atherosclerosis	Altered Intercellular Communication	The relationship between inflammation, obesity and risk for hypertension in the Multi-Ethnic Study of Atherosclerosis (MESA).	20944659
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	It has been suggested that inflammation is important in the aetiology of hypertension and that this may be most relevant among obese persons.	20944659
Hypertension, CTCAE	Altered Intercellular Communication	The relationship between inflammation-related proteins and hypertension risk was predominantly explained by other hypertension risk factors.	20944659
Inflammation, Hypertension, CTCAE, Obesity	Altered Intercellular Communication	Obesity, independent of inflammation, remained a potent risk factor for future hypertension.	20944659
Autoinflammatory Syndrome, Inflammation, Neoplasm Metastasis, Rheumatoid Arthritis, Inflammatory disorder, Tenosynovitis	Altered Intercellular Communication	It is called inflammatory Brown syndrome, a secondary disorder, which main causes are local inflammation in the orbit and inflammatory diseases such as rheumatoid arthritis and tenosynovitis.	20944946
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	The mechanisms by which OSAS can affect the cardiovascular system are multiple, including the activation of the sympathetic nervous system, systemic inflammation, insulin resistance, and oxidative stress.	20944980
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation and oxidative stress are associated with atrial fibrillation (AF).	20946227
Atrial Fibrillation, Inflammation	Altered Intercellular Communication	We tested if atorvastatin reduced AF recurrence after DC cardioversion (CV) by modifying systemic oxidative stress and inflammation (NCT00252967).	20946227
Inflammation	Altered Intercellular Communication	It reduced selective markers of inflammation without affecting systemic oxidative stress.	20946227
Kidney Failure, Chronic, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Hemodiafiltration with regeneration of ultrafiltrate (HFR) has a positive impact on inflammation and oxidative stress (OxSt), risk factors for cardiovascular disease (CVD), the most common cause of excess morbidity and mortality for end-stage renal disease (ESRD) patients.	20946294
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, atherosclerotic	Altered Intercellular Communication	Given the strong relationships between OxSt and inflammation with CVD, their reduction might provide a beneficial impact by reducing the risk of atherosclerotic CVD in dialysis patients.	20946294
Hyperthyroidism, Inflammation, Neoplasms, Hypothyroidism	Altered Intercellular Communication	In order to achieve better orientation in the processing of results, the patient-described types of disorders were classified according to the patients' own opinions into the following groups: eufunctional thyroid gland, inflammation, hypothyroidism, hyperthyroidism, tumour and surgery.	20946722
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Oxidative conditions such as inflammation and diabetes are the major determinants of FORT values in patients with AMI.	20947086
Data types - Address	Altered Intercellular Communication	Our findings suggest that reduced inhibitory neurotransmission during aging and in AD may be the result of compensatory responses that, paradoxically, render the neurons vulnerable to Ca(2+)-mediated degeneration.	20947216
Communicable Diseases, Inflammation, Traumatic injury, Malignant Neoplasms	Altered Intercellular Communication	Pathologic processes presenting with limping include trauma, inflammation, infection, and malignancy.	20947283
ARCN1 gene, Inflammation, Atherosclerosis, Chronic Obstructive Airway Disease, Endothelial dysfunction	Altered Intercellular Communication	The relationship between chronic obstructive pulmonary disease (COPD) and atherosclerosis has been suggested; this association may relate to systemic inflammation and endothelial dysfunction, which can lead to alteration of small pulmonary vessels.	20947389
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Systemic inflammation and endothelial dysfunction may cause the close relationship between atherosclerosis and small pulmonary vessel alteration.	20947389
ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	Seven patients with chronic obstructive pulmonary disease (COPD) and three patients with acute lung inflammation served as control groups.	20947455
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	Lactate was lower (1.6+-0.8mmol/L) in sputa from seven COPD patients, and it was below the detection limit in three patients with acute lung inflammation.	20947455
Adenocarcinoma, Neoplasms	Altered Intercellular Communication	We measured the expression of 23 inflammation-associated genes in tumors and adjacent normal tissues from 93 patients (58 Barrett's and 35 Sporadic adenocarcinomas) by quantitative reverse transcription-polymerase chain reaction.	20947516
Inflammation, Pleural effusion disorder	Altered Intercellular Communication	Thrombin-antithrombin III complex, proinflammatory cytokines, and fibrinolytic indices for assessing the severity of inflammation in pleural effusions.	20947808
Inflammation, Pleural effusion disorder	Altered Intercellular Communication	In conclusion, TNF-a and PAI-1 are important indicators in patients with tuberculous pleural effusions, and measurement of TAT is useful for assessing the severity of inflammation in pleural fluids.	20947808
Inflammation, Headache	Altered Intercellular Communication	Headache due to the pressure of nasal mucosa in the absence of inflammation of the nose and paranasal sinuses is a clinical entity that has gained wide acceptance.	20948593
Inflammation	Altered Intercellular Communication	Histology revealed hypodermic granulomatous inflammation with predominantly macrophage and eosinophils.	20949344
Granulomatous inflammation, Blastomycosis, Mycoses	Altered Intercellular Communication	Fine-needle aspiration of the thyroid demonstrated 10-20 mm broad-based budding yeasts with thick-walled, refractile capsules amidst a background of granulomatous inflammation, and was diagnosed as a fungal infection consistent with blastomycosis.	20949466
Granulomatous inflammation	Altered Intercellular Communication	Fungal and mycobacterial cultures and special stains for fungal organisms should be requested on all thyroid fine-needle aspiration biopsies with granulomatous inflammation.	20949466
Inflammation, Weight decreased	Altered Intercellular Communication	Our findings did not provide any evidence for a role of visfatin increase on low-grade inflammation after weight loss.	20951014
Inflammation, Atherosclerosis	Altered Intercellular Communication	Resistin is an adipocytokine involved in insulin resistance, inflammation, and atherosclerosis.	20951381
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Adjustment for inflammatory markers attenuated these associations, suggesting a possible role for resistin in inflammation and CHD pathophysiology.	20951381
Inflammation	Altered Intercellular Communication	Chronic and acute stress, with associated pathophysiology, are implicated in a variety of disease states, with neuroimmunological dysregulation and inflammation as major hazards to health and functional sufficiency.	20953749
Inflammation	Altered Intercellular Communication	Chronic conditions of stress and affective dysregulation are associated with neuroimmunological insufficiency and inflammation, contributing to health risk and mortality.	20953749
Inflammation, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Moreover, they had more advanced fibrosis, portal inflammation, interface hepatitis, and proliferation of bile ductules (P = 0.008, P = 0.008, P = 0.019, and P = 0.027, respectively).	20954280
Inflammation, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	ANEA positive, anti-gp210 negative patients had a difference in AMA titer (<= 1:160/> 1:160 50%/50% vs 71.8%/28.2%, P = 0.002), stage (I-II/III-IV 57.9%/42.1% vs 74.4%/25.6%, P = 0.033), fibrosis (P = 0.009), portal inflammation (P = 0.018), interface hepatitis (P = 0.032), and proliferation of bile ductules (P = 0.031).	20954280
Inflammation, Carcinoma of lung, Neoplasms	Altered Intercellular Communication	There is emerging evidence that chronic inflammation may play a significant role in the pathogenesis of lung cancer as a tumor promoter.	20954376
Heart Diseases, Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Reduced albumin may be a marker of chronic systemic inflammation, which may be the mechanism for cardiopathy and bad outcome of stroke.	20954836
Inflammation, Erectile dysfunction	Altered Intercellular Communication	Previous studies have suggested that erectile dysfunction (ED) is associated with chronic inflammation, which is also a principle mechanism of carcinogensis.	20955312
Inflammation, Hypercholesterolemia	Altered Intercellular Communication	Our results indicate that low-grade systemic inflammation and monocyte secretory function are disturbed to a similar degree in the patients with isolated hypercholesterolaemia and in the patients with IFG.	20955358
Inflammation, Thrombosis	Altered Intercellular Communication	In the current case, the factors possibly associated with increased risk for dissection may include dilatation of the pulmonary artery, local inflammation favoured by in situ thrombosis, and acute increase of pulmonary pressure secondary to physical exertion.	20956141
Malignant mesothelioma, Inflammation	Altered Intercellular Communication	Asbestos-induced chronic inflammation is implicated in the pathogenesis of malignant mesothelioma (MM).	20956618
Periodontal Diseases, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Treatment of periodontal disease may reduce cardiovascular risk in the longer term, but studies have suggested a link among dental procedures, acute inflammation, and endothelial dysfunction.	20956706
Stomach Carcinoma, Communicable Diseases, Helicobacter pylori, Inflammation	Altered Intercellular Communication	Gastric cancer commonly follows a long-standing inflammation, mainly due to Helicobacter pylori (HP) infection.	20956764
Degenerative polyarthritis, Pain Distress Question, Inflammation	Altered Intercellular Communication	To assess experimental pain sensitivity and compare the inflammatory response to pain in 26 osteoarthritis (OA) patients and 33 age- and sex-matched controls from the general population in order to examine the nature of the association between pain and inflammation in OA.	20957660
Autoimmune Diseases, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Apart from a significant increase in our understanding of the mechanisms for uptake, cell clearance is a basic mechanism in tissue homeostasis, cancer, resolution of inflammation, induction of tolerance, and autoimmunity.	20958309
Acidophil Stem Cell Pituitary Gland Adenoma, Acromegaly, Neoplasms	Altered Intercellular Communication	Fugitive acromegaly is most commonly caused by pituitary acidophil stem cell adenomas, and is characterized by a relatively short clinical history, a large and locally invasive tumor, and relatively low hormonal activity.	20960094
Inflammation	Altered Intercellular Communication	The systemic inflammation induced by common cytokines may explain the linkage between the two conditions.	20960105
Inflammation, Neck Pain	Altered Intercellular Communication	Case report of an 85-year-old patient with acute neck pain and elevated parameters of inflammation in the blood.	20960401
Inflammation	Altered Intercellular Communication	S. aureus may play an important role in the pathogenesis of NP via tissue remodeling as well as eosinophilic inflammation.	20961499
Inflammation, Metabolic Syndrome X, Cardiovascular Diseases, Restless Legs Syndrome, Obesity, Hypertension, CTCAE	Altered Intercellular Communication	RLS was not associated with symptoms of the metabolic syndrome like hypertension, obesity, markers of systemic inflammation (IL-6 and CRP) or cardiovascular diseases.	20961808
Inflammation, Metabolic Syndrome X, Cardiovascular Diseases, Restless Legs Syndrome, Obesity, Hypertension, CTCAE	Altered Intercellular Communication	RLS was not associated with markers of the metabolic syndrome like hypertension, obesity, cardiovascular diseases or biomarkers of systemic inflammation.	20961808
Inflammation, Diarrhea, Helminths	Altered Intercellular Communication	We measured changes in hemoglobin concentrations, inflammation, iron status, helminths, diarrhea, fecal calprotectin concentrations, and microbiota diversity and composition (n = 60) and the prevalence of selected enteropathogens.	20962160
Inflammation	Altered Intercellular Communication	Thus, iron fortification in this population produces a potentially more pathogenic gut microbiota profile, and this profile is associated with increased gut inflammation.	20962160
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Regulatory B cells control inflammation and autoimmunity in mice, including the recently identified IL-10-competent B10 cell subset that represents 1% to 3% of spleen B cells.	20962324
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	However, the frequency and types of inflammation in upper gastrointestinal biopsies in patients with UC has not been well studied, especially in a controlled study.	20962621
Gastritis, Ulcerative Colitis	Altered Intercellular Communication	There were 3 types of gastric inflammation that occurred more in UC patients than in controls, and the differences were statistically significant.	20962621
Inflammation, Ulcerative Colitis, Plasmacytosis	Altered Intercellular Communication	Twenty-two percent of UC patients had a basal mixed inflammation compared with 8% of controls, and 20% of the UC patients had superficial plasmacytosis compared with 6% of controls.	20962621
Ulcerative Colitis	Altered Intercellular Communication	Most UC patients have no upper gastrointestinal inflammation in biopsies, and most of the inflammations they have are not unique.	20962621
Inflammation, Ulcerative Colitis, Gastritis, Plasmacytosis	Altered Intercellular Communication	The most common upper gastrointestinal inflammatory pattern in patients with UC is focal gastritis, followed by gastric basal mixed inflammation and superficial plasmacytosis.	20962621
Pouchitis, Duodenitis, Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	The one unique upper gastrointestinal inflammation in UC patients is diffuse chronic duodenitis, present in 10% of patients who had duodenal biopsies, and in 40% of UC patients who had colectomy and all of these patients had pouchitis.	20962621
Esophagitis, Ulcerative Colitis	Altered Intercellular Communication	There were no esophageal inflammations that occurred more commonly in UC than controls.	20962621
Ulcerative Colitis	Altered Intercellular Communication	Most UC patients have no upper gastrointestinal inflammation in biopsies, and most of the inflammations they have are not unique.	20962621
Nephritis, Kidney Diseases	Altered Intercellular Communication	This suggested that intrarenal inflammation might accelerate Alport nephropathy.	20962742
Nephritis	Altered Intercellular Communication	Thus, systemic exposure to CpG-DNA induces classically activated (M1) macrophages that enhance intrarenal inflammation and disease progression.	20962742
Arterial Stiffness, Inflammation, Antihypertensive Agents	Altered Intercellular Communication	The diverse associations of uric acid with low-grade inflammation, adiponectin and arterial stiffness in never-treated hypertensives.	20962858
Hypertensive disease, Inflammation	Altered Intercellular Communication	The data regarding the role of serum uric acid (SUA) along with subclinical inflammation in the context of hypertensive vascular damage are rather scarce and controversial.	20962858
Inflammation, Atherosclerosis, Diabetes Mellitus, Chronic disease, Malignant Neoplasms	Altered Intercellular Communication	Chronic inflammation has been implicated in the pathogenesis of several chronic diseases, such as atherosclerosis and diabetes, as well as certain types of cancers.	20962912
Inflammation	Altered Intercellular Communication	It has been suggested that circulating biomarkers for inflammation may be modified by exercise; however, few laboratory-based studies have been conducted in nonobese premenopausal women.	20962912
Inflammation	Altered Intercellular Communication	Macrophage staining for PON1 and PON3 was significantly and positively related to the amount of aortic inflammation (both P<0*001).	20964682
Inflammation, Autonomic nervous system disorders	Altered Intercellular Communication	Inflammation, platelet reactivity and cardiac autonomic dysfunction increase the risk of cardiovascular events, but the relationships between these prognostic markers are poorly defined.	20964738
Inflammation, Weight decreased, Fracture	Altered Intercellular Communication	The final outcomes of this trial will assist clinicians in the development of effective and alternative treatment methods post proximal femoral fracture surgery which may ultimately result in a reduction in systemic inflammation, loss of weight and lean muscle and improvements in nutritional status, mobility, independence and quality of life among elderly patients.	20964865
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Results suggest that exposure to quasi-ultrafine particles and combustion-related pollutants (predominantly from traffic) increase the risk of myocardial ischemia, coherent with our previous findings for systemic inflammation and blood pressure.	20965803
Coughing, Airway structure	Altered Intercellular Communication	Previous work has suggested that cough may be linked to neutrophilic airway inflammation.	20965928
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation may play a significant role in the pathogenesis of atrial fibrillation (AF).	20965978
Inflammation, Fibrosis Assessment, Lung diseases	Altered Intercellular Communication	After a 27-year interval, two subjects with manifestations of preclinical familial pulmonary fibrosis, including asymptomatic alveolar inflammation and alveolar macrophage activation, were reevaluated for lung disease.	20966039
Inflammation, Fibrosis Assessment, Lung diseases, Kidney Failure	Altered Intercellular Communication	In familial pulmonary fibrosis, asymptomatic preclinical alveolar inflammation associated with mutation in TERT and telomerase insufficiency can progress to fibrotic lung disease over 2 to 3 decades.	20966039
Airway structure, Pulmonary Emphysema	Altered Intercellular Communication	Persistent airway inflammation and emphysema progression on CT scan in ex-smokers observed for 4 years.	20966041
Airway structure	Altered Intercellular Communication	Whether discontinuing smoking for at least 4 years halts airway inflammation and progression of COPD-E in prior smokers is unknown.	20966041
Airway structure	Altered Intercellular Communication	Cessation of tobacco smoking in heavy smokers with moderately severe COPD-E is associated with evidence of persistent airway inflammation and progression of COPD-E on CT scan 4 years later.	20966041
Airway structure	Altered Intercellular Communication	Discontinuing smoking may slow the rate of progression of moderate severity COPD-E, but it does not prevent persistent airway inflammation and significant progression of COPD-E on CT scan.	20966041
Inflammation, Fibrosis Assessment, Endothelial dysfunction, Hypertrophy, Cardiovascular system	Altered Intercellular Communication	Cardiovascular signs included increased systolic blood pressure and endothelial dysfunction together with inflammation, fibrosis, hypertrophy, increased stiffness, and delayed repolarization in the left ventricle of the heart.	20966763
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The liver showed increased wet weight, fat deposition, inflammation, and fibrosis with increased plasma activity of liver enzymes.	20966763
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The kidneys showed inflammation and fibrosis, whereas the pancreas showed increased islet size.	20966763
Intestinal metaplasia, Inflammation, Gastritis, Atrophic	Altered Intercellular Communication	Histological assessment showed alleviation of chronic inflammation in all subjects (p < 0.0001), while such a change was not observed for four subjects showing severe gastric atrophy and intestinal metaplasia.	20967557
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Downregulation of serum EGF may be correlated with different patterns of bowel inflammation, epithelial development, and wound healing in IBD.	20969541
Chronic Kidney Diseases	Altered Intercellular Communication	Posttransplant inflammation associated with onset of chronic kidney disease.	20970563
Inflammation, Tumor necrosis	Altered Intercellular Communication	The following markers of inflammation (MIF) were determined pretransplant and at 3 months after grafting: C-reactive protein (CRP) (mg/L), interleukin (IL)-6 (pg/mL), IL-10 (pg/mL), tumor necrosis factor (TNF)-a (pg/mL), and its soluble receptor (ng/mL), soluble-IL2R (UI/mL), pregnancy-associated plasma protein A (PAPP-A; mUI/L), and IL-4 (pg/mL).	20970563
Inflammation, Canada	Altered Intercellular Communication	Patients with CAN showed worse inflammation, eg, MIF ratios over one, with statistically significant differences for the ratios of TNF-a and PAPP-A (P=.032 and P=.051 respectively).	20970563
Inflammation, Canada	Altered Intercellular Communication	Among other factors, inflammation may determine the onset of CAN as diagnosed by renal biopsy.	20970563
Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	Inflammation, metalloproteinases, and growth factors in the development of carotid atherosclerosis in renal transplant patients.	20970566
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is associated with neutrophil-mediated inflammation, a potential target for treatment in COPD.	20970976
Keratoconjunctivitis, Vernal, allergic inflammation	Altered Intercellular Communication	Vernal keratoconjunctivitis (VKC) is a recurrent, chronic allergic inflammation of the ocular surface associated with remodeling of the cornea and conjunctiva, with a potential to adversely affect the patient's vision and quality of life.	20971677
Inflammation, destruction joint, Arthritis	Altered Intercellular Communication	Silencing the expression of Ras family GTPase homologues decreases inflammation and joint destruction in experimental arthritis.	20971740
Inflammation, destruction joint, Arthritis	Altered Intercellular Communication	The overlap in contributions of Ras homologues to FLS activation suggests that broad targeting of Ras GTPases in vivo suppresses global inflammation and joint destruction in arthritis.	20971740
Inflammation, destruction joint, Arthritis, Collagen-Induced	Altered Intercellular Communication	Consistent with this, simultaneous silencing of H-Ras, K-Ras, and N-Ras expression significantly reduces inflammation and joint destruction in murine collagen-induced arthritis, while specific targeting of N-Ras alone is less effective in providing clinical benefits.	20971740
Inflammation, Intracranial Aneurysm, Rupture	Altered Intercellular Communication	Inflammation and activation of the complement system predispose to intracranial artery aneurysm (IA) rupture.	20971742
Experimental Organism Luteinized Unruptured Follicle, Inflammation, Rupture	Altered Intercellular Communication	Because disturbances in complement regulation may lead to increased susceptibility to complement activation and inflammation, we looked for evidence for dysregulation of the complement system in 26 unruptured and 26 ruptured IAs resected intraoperatively.	20971742
Tissue damage, Inflammation	Altered Intercellular Communication	Apparently, disturbed complement regulation leads to an increased susceptibility to complement activation, inflammation, and tissue damage in the IA wall.	20971742
Inflammation, Ulcerative Colitis, interferon beta-1a	Altered Intercellular Communication	Suppression of inflammation in ulcerative colitis by interferon-b-1a is accompanied by inhibition of IL-13 production.	20971977
Inflammation, Atherosclerosis	Altered Intercellular Communication	While it is well documented that inflammation is an important risk factor for vascular pathophysiology, the association of bacteria with atherosclerosis has not been clearly established, in large part due to the inability to isolate live bacteria from atheromatous tissue.	20972353
Inflammation, Dental Plaque	Altered Intercellular Communication	Characterization of carotid artery plaques with USPIO-enhanced MRI: assessment of inflammation and vascularity as in vivo imaging biomarkers for plaque vulnerability.	20972832
Dermatitis, Atopic, Inflammation, Data types - Address	Altered Intercellular Communication	A subgroup of patients with atopic dermatitis (AD) produces IgE autoantibodies to human proteins which may be present in inflamed skin and perpetuate cutaneous inflammation.	20973764
Inflammation, Data types - Address	Altered Intercellular Communication	These TCC produce not only Th2 but also Th1 cytokines which may explain the Th1 phenotype of inflammation in AD.	20973764
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	A retrospective study: correlation of histologic inflammation in biopsy specimens of Chinese men undergoing surgery for benign prostatic hyperplasia with serum prostate-specific antigen.	20974483
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	To reveal the correlation between benign prostatic hyperplasia (BPH) histologic inflammation and serum prostate-specific antigen (sPSA) concentrations, and the possible mechanism.	20974483
Inflammation, Leucocytic infiltrate, prostatitis	Altered Intercellular Communication	According to the histopathological classification system for chronic prostatic inflammation proposed by the Chronic Prostatitis Collaborative Research Network (CPCRN) and the International Prostatitis Collaborative Network (IPCN), we classified the histologic sections of prostatic biopsy into glandular, periglandular, and stromal inflammation by the anatomical location of inflammatory infiltration.	20974483
Inflammation, Aggressive behavior	Altered Intercellular Communication	The glandular inflammation was graded according to the inflammatory aggressiveness.	20974483
Inflammation	Altered Intercellular Communication	The periglandular and stromal inflammation were graded according to the inflammatory density.	20974483
Inflammation	Altered Intercellular Communication	Single regression analysis revealed that total prostatic volume, the aggressiveness of glandular inflammation, and the intensity of periglandular and stromal inflammation were correlated with sPSA.	20974483
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	Alkylation of the tumor suppressor PTEN activates Akt and b-catenin signaling: a mechanism linking inflammation and oxidative stress with cancer.	20975834
Inflammation, Hyperplasia, Neoplastic disease	Altered Intercellular Communication	Alkylation of PTEN by a,b-enals/enones and interference with its restraint of cellular PKB/Akt signaling may accentuate hyperplastic and neoplastic disorders associated with chronic inflammation, oxidative stress, or aging.	20975834
Colorectal Carcinoma	Altered Intercellular Communication	Comparison of positive lymph node ratio with an inflammation-based prognostic score in colorectal cancer.	20976703
Colorectal Carcinoma	Altered Intercellular Communication	Two prognostic scoring systems have been proposed in colorectal cancer: the pathologically based positive lymph node ratio (pLNR) and the inflammation-based modified Glasgow Prognostic Score (mGPS).	20976703
Neuronal loss in central nervous system, MS gene, Meningitis	Altered Intercellular Communication	A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis.	20976767
Inflammation, MS gene	Altered Intercellular Communication	Prominent inflammation with formation of ectopic B-cell follicle-like structures in the meninges in secondary progressive multiple sclerosis (MS) (SPMS) is associated with extensive cortical pathology and an exacerbated disease course.	20976767
Damage, Meningitis	Altered Intercellular Communication	Our objective was to evaluate the cellular substrates of the cortical damage to understand the role of meningeal inflammation in MS pathology.	20976767
Loss, Nerve Degeneration, Meningitis	Altered Intercellular Communication	We demonstrate substantial cortical neurodegeneration and generalized cell loss in progressive MS in association with meningeal inflammation and lymphoid tissue formation, supporting the hypothesis that cytotoxic factors diffusing from the meningeal compartment contribute to grey matter pathology and the consequent increase in clinical disability.	20976767
Inflammation, Infection	Altered Intercellular Communication	As the disease progresses, frequent infections and inflammation initiate destruction of the parenchyma leading to chronic obstruction of the airways.	20977128
Asthma, Bronchitis	Altered Intercellular Communication	Fractional exhaled nitric oxide (FeNO) is a non-invasive marker of bronchial inflammation in asthma.	20977500
Bronchitis	Altered Intercellular Communication	Optimal clinical control of infantile wheeze appeared to be associated with the control of bronchial inflammation when evaluated by FeNO measurements.	20977500
Inflammation	Altered Intercellular Communication	Further characterization of common and lower-frequency genetic variants that contribute to interpopulation differences in fibrinogen phenotype may help refine our understanding of the contribution of hemostasis and inflammation to atherothrombotic risk.	20978265
Inflammation, Asthma	Altered Intercellular Communication	Leptin levels correlated with the clinical severity of asthma and this was suggested to be associated with the severity of inflammation in asthma.	20978869
Inflammation, Pneumonia	Altered Intercellular Communication	In this patient, the increased circulating cortisol associated with the stress of inflammation caused by pneumonia triggered the development of pseudoaldosteronism.	20979951
Superficial ulcer, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	No overall progression and occasional repair of erosions despite persistent inflammation in adalimumab-treated rheumatoid arthritis patients: results from a longitudinal comparative MRI, ultrasonography, CT and radiography study.	20980282
Refractory anemias, Inflammation, Rheumatoid Arthritis, Destruction (action)	Altered Intercellular Communication	To monitor joint inflammation and destruction in rheumatoid arthritis (RA) patients receiving adalimumab/methotrexate combination therapy using MRI and ultrasonography.	20980282
Inflammation, Edema	Altered Intercellular Communication	Inflammation on MRI and ultrasonography, especially MRI bone oedema, was predictive for erosive progression on CT, at bone/joint level and MRI bone oedema also at patient level.	20980282
Inflammation	Altered Intercellular Communication	Insufficient role of cell proliferation in aberrant DNA methylation induction and involvement of specific types of inflammation.	20980348
Inflammation	Altered Intercellular Communication	Chronic inflammation is deeply involved in induction of aberrant DNA methylation, but it is unclear whether any type of persistent inflammation can induce methylation and how induction of cell proliferation is involved.	20980348
Inflammation, Helicobacter, Neutrophil Infiltration	Altered Intercellular Communication	After 20 weeks, chronic inflammation with lymphocyte and macrophage infiltration was prominent in the three Helicobacter groups, whereas neutrophil infiltration was mainly observed in the EtOH and NaCl groups.	20980348
Helicobacter	Altered Intercellular Communication	Among the inflammation-related genes, Il1b, Nos2 and Tnf showed increased expression specifically in the three Helicobacter groups.	20980348
Communicable Diseases, Helicobacter, Inflammation	Altered Intercellular Communication	These data showed that inflammation due to infection of the three Helicobacter strains has a strong potential to induce methylation, regardless of their CagA statuses, and increased cell proliferation was not sufficient for methylation induction.	20980348
Inflammation	Altered Intercellular Communication	It was suggested that specific types of inflammation characterized by expression of specific inflammation-related genes, along with increased cell proliferation, are necessary for methylation induction.	20980348
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Reduced vitality and enhanced ECC formation suggest growth induction of impaired EPCs in chronic renal failure and are associated with inflammation.	20980359
Inflammation, Arthritis, Psoriatic	Altered Intercellular Communication	Inflammation in an individual joint predicts damage to that joint in psoriatic arthritis.	20980703
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Systemic inflammation (SI) plays a pivotal role in cancer.	20981494
Inflammation, Atherosclerosis	Altered Intercellular Communication	The renin angiotensin aldosterone system (RAAS) induces inflammation and accelerates atherosclerosis, contributes to both pro- and anti-inflammatory cytokines.	21028999
Inflammation	Altered Intercellular Communication	C-reactive protein (CRP) not only reflects an inflammatory state but also leads to inflammation.	21028999
Inflammation, Sialectasia NOS	Altered Intercellular Communication	The clinical criteria applied included the coexistence of multiple lesions and mucoid/purulent discharge, while the histopathological criteria included two or more of the following findings: sialectasia, chronic inflammation, mucous/oncocytic metaplasia and mucin in ducts.	21029266
Cerebrovascular Disorders, Inflammation	Altered Intercellular Communication	Influence of prophylactic, endovascularly based normothermia on inflammation in patients with severe cerebrovascular disease: a prospective, randomized trial.	21030704
Inflammation, Hyperplasia	Altered Intercellular Communication	The present results arouse suspicion of local inflammation of the aortic wall, but with moderate progress under strong hyperplasia.	21030919
Rupture, Inflammation, Acute Disease	Altered Intercellular Communication	Because of rupture of the intima, the inflammation appears as an acute disease.	21030919
Glaucoma, Primary Open Angle, Inflammation, Humor	Altered Intercellular Communication	The aqueous humor Hep level may exist locally and independent from the IL6 increase in patients with POAG, suggesting that Hep might represent a bridge protein between local inflammation and the consequent loss of retinal ganglion cells.	21031015
Inflammation	Altered Intercellular Communication	It can therefore be concluded that both changes represent the mucosa's reaction to recurrent or chronic inflammation.	21031334
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	The identified genes elucidate differences in inflammation between stroke subtypes.	21031583
Inflammation	Altered Intercellular Communication	Chronic inflammation in dialysis patients increases the production of cytokines such as TNF-a, IL-1b and IFN- IFN-g and there is evidence of a significant mortality rate in dialysis patients due to inflammation.	21031623
Inflammation, Cholangitis, Neoplasms	Altered Intercellular Communication	1CTP level tended to be higher in patients with cholangitis compared to those with no inflammation or benign tumors (p = 0.065).	21033212
Inflammatory, Crohn Disease, Chronic disease, Ulcerative Colitis	Altered Intercellular Communication	Non specific inflammations of the intestine are the group of chronic disorders, such as ulcerative colitis and Crohn's disease and with episodic aggravation of inflammatory lesions, called active phase and non-active phase, called remission.	21033410
Intraocular inflammation	Altered Intercellular Communication	Regarding the primary efficacy variable, intraocular inflammation, no microbial events were recorded, but aqueous flare was significantly lower with Tobramycin/Dexamethasone at 1 week (P = 0.002).	21034176
Postoperative infection, Acute inflammation	Altered Intercellular Communication	Both the studied fixed combinations are safe and effective in controlling postoperative inflammation and preventing postoperative ocular infections.	21034176
Intraocular inflammation, Retinitis	Altered Intercellular Communication	Intraocular inflammation was completely quiescent until 1 year following the implant, when he developed retinitis.	21034309
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation resolved with systemic and topical steroid.	21034312
Inflammation, Ischemic stroke	Altered Intercellular Communication	Systemic markers of inflammation are independently associated with S100B concentration: results of an observational study in subjects with acute ischaemic stroke.	21034449
Inflammation, Brain Injuries, physiopathological, Acute Cerebrovascular Accidents	Altered Intercellular Communication	Vascular dysfunction and brain inflammation are thought to contribute to the pathophysiology of cerebral injury in acute stroke.	21034449
Inflammation, Lesion of brain, Brain Injuries, physiopathological	Altered Intercellular Communication	However acute inflammation and vascular dysfunction may simply be markers of an acute phase response to cerebral injury, reflecting the size of the cerebral lesion.	21034449
Inflammation, Brain Injuries, Ischemic stroke, physiopathological	Altered Intercellular Communication	We aimed to determine if systemic markers of vascular dysfunction and inflammation are independently associated with concentrations of the astroglial protein S100B, a marker of brain injury, in participants with acute ischaemic stroke.	21034449
Inflammation, Ischemic, Ischemic stroke	Altered Intercellular Communication	The degree of systemic inflammation is associated with S100B concentration in acute ischaemic stroke, independent of the size of the ischaemic lesion.	21034449
Inflammation, Critical Illness	Altered Intercellular Communication	Likewise, the neutrophil-lymphocyte count ratio (NLCR) has been shown a simple promising method to evaluate systemic inflammation in critically ill patients.	21034463
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal tract.	21035384
Inflammatory Bowel Diseases, Inflammatory disease of mucous membrane	Altered Intercellular Communication	EBV replication was associated with severe IBD and mucosal inflammation.	21035384
Communicable Diseases, Inflammation	Altered Intercellular Communication	Increased proliferation and EBV infection of B-lymphocytes in inflamed colonic mucosa highlight the potential role of EBV in mucosal inflammation.	21035384
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	The immunomodulatory effects of EBV could delay the resolution of the IBD associated inflammation, thus contributing to disease progression.	21035384
Inflammation, RPS6KA2 protein, human	Altered Intercellular Communication	RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 are involved in several pathways central to the carcinogenic process, including regulation of cell growth, insulin, and inflammation.	21035469
Eosinophilic disorder, Inflammation, Hypereosinophilic syndrome	Altered Intercellular Communication	Hypereosinophilic syndromes (HES) are a heterogeneous group of conditions that are characterized by tissue-associated eosinophilic inflammation and peripheral eosinophilia.	21036585
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by progressive inflammation in the airways and lungs combined with disturbed homeostatic functions of pulmonary cells.	21037022
Inflammation, Unipolar Depression	Altered Intercellular Communication	We aimed to determine whether subclinical systemic inflammation, as measured by serum high-sensitivity C-reactive protein (hsCRP) concentration, is associated with an increased risk of de novo major depressive disorder.	21037214
Airway structure, ARCN1 gene	Altered Intercellular Communication	Assessment of airway inflammation using sputum, BAL, and endobronchial biopsies in current and ex-smokers with established COPD.	21037956
ARCN1 gene, Airway structure	Altered Intercellular Communication	However, there is little known in COPD about the detailed interrelationships between lung function and inflammatory profiles in different airway compartments from the same individual and whether airway inflammation in these different compartments differs in ex- and current smokers with established COPD.	21037956
Airway structure, ARCN1 gene	Altered Intercellular Communication	Airway inflammation persists in ex-smokers with COPD, but differs from COPD current smokers.	21037956
Inflammation, Autoimmune Chronic Hepatitis, Liver Cirrhosis	Altered Intercellular Communication	Autoimmune hepatitis is characterized by hepatocellular inflammation often progressing to cirrhosis.	21037986
Inflammation, Asthma	Altered Intercellular Communication	Phlegm, which is considered by Chinese medicine as an inveterate root of asthma, might be closely related with the inflammation in modern medicine.	21038651
Airway structure, Asthma	Altered Intercellular Communication	High serum arginase I levels in asthmatic patients may be associated with airway inflammation in non-atopic asthma.	21039185
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	Fungi and/or Staphylococcus aureus enterotoxins (SEs) may participate in the pathogenesis of eosinophilic inflammation in cases of chronic rhinosinusitis with nasal polyps (CRSwNP).	21039976
Inflammation, Lung Diseases, Interstitial, Fibrosis Assessment, Hyperplasia	Altered Intercellular Communication	Idiopathic interstitial lung diseases (iILDs) are characterized by inflammation, hyperplasia of Type-II alveolar epithelial cells (AECs) and lung remodelling often with progressive fibrosis.	21039988
Inflammation	Altered Intercellular Communication	Lower serum high-density lipoprotein cholesterol (HDL-C) is associated with inflammation, insulin resistance and poor cardiovascular outcomes in the general population.	21040164
Inflammation, Osteopenia	Altered Intercellular Communication	In addition, no correlation was found between the fluid levels of molecules promoting inflammation and osteoclastic activity and the extent of bone loss in the hip (in terms of Saleh's classification) or the knee (AORI classification).	21040654
Inflammation, Family history, Atherosclerosis	Altered Intercellular Communication	We hypothesized that children with FH, as a model of early atherosclerosis, have different serum levels of inflammation markers than healthy control children.	21040915
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Pericardial fat inflammation correlates with coronary artery disease.	21040916
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	We sought to assess the association between inflammation in pericardial fat (PF) and coronary artery disease (CAD) by pathological examination and clinical evaluation with cardiac computed tomography (CT).	21040916
Acute Coronary Syndrome, Inflammation	Altered Intercellular Communication	The CT density of PF around culprit lesions was significantly higher than non-culprit lesions in patients with acute coronary syndromes (-72 +- 11 vs. -82 +- 14 HU, p=0.002), which may reflect PF inflammation.	21040916
Inflammation, Hypertension, CTCAE, Dyslipidemias, Diabetes Mellitus	Altered Intercellular Communication	Multiple logistic regression analysis demonstrated that the PF inflammation index (PFI; PDG x PF volume, which could be the integrated index of inflammatory activity and abundance of PF) was significantly associated with the presence of CAD (odds ratio [95% confidence interval]; 1.234 [1.012-1.503] per 1000 HU cm(3), p=0.037) independent of other metabolic risk factors such as hypertension, dyslipidemia, and diabetes.	21040916
Inflammation	Altered Intercellular Communication	PF inflammation may be involved in pathogenesis of CAD.	21040916
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Attenuation by adipose tissue-associated inflammation, endothelial dysfunction, and NEFA was more modest (20.7%, 13.1%, and 9.5%, respectively).	21040936
Inflammation, Non-alcoholic Fatty Liver Disease, Endothelial dysfunction, Metabolic Syndrome X	Altered Intercellular Communication	Insulin resistance constitutes a key pathophysiological mechanism in the association between the metabolic syndrome and NAFLD (measured as ALT), which may operate through adipose tissue-associated inflammation and endothelial dysfunction and to a lesser extent through NEFA, which may have an independent role in the development of NAFLD in subjects with the metabolic syndrome.	21040936
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Effect of atorvastatin on inflammation and modification of vascular risk factors in rheumatoid arthritis.	21041278
Inflammation, Refractory anemias, Rheumatoid Arthritis, Endothelial dysfunction, Arterial Stiffness	Altered Intercellular Communication	To investigate the effect of atorvastatin therapy on inflammation, disease activity, endothelial dysfunction, and arterial stiffness in patients with rheumatoid arthritis (RA).	21041278
Inflammation, hepcidin, Neoplasms	Altered Intercellular Communication	Parallel variations of plasma IL-6, C-reactive protein, and hepcidin concentrations, together with tumor immunohistochemistry, strongly suggested that IL-6 synthesized by the tumor caused both the inflammation and iron deficiency through enhancement of hepcidin production by the liver.	21041280
Inflammation, Tissue Adhesions	Altered Intercellular Communication	The etiology of these fistulae is uncertain, but is thought to be related to post surgical injury and inflammation leading to adhesions and neorevascularization.	21041861
vascular inflammations	Altered Intercellular Communication	Serum adipocytokine and vascular inflammation marker levels in Beta-thalassaemia major patients.	21042009
vascular inflammations, beta Thalassemia	Altered Intercellular Communication	We aimed to analyze the levels of these adipocytokines and determine any possible correlations with disease severity or vascular inflammation markers in beta-thalassaemia.	21042009
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	A marker of low grade inflammation provides useful predictive ability beyond other simple predictors in a female population with MetS prevailing.	21042044
methyldopa, Inflammation	Altered Intercellular Communication	In addition to hemostasis, TF can initiate intracellular signaling and promote inflammation and angiogenesis, the key processes underlying the pathogenesis of age-related macular degeneration (AMD).	21042291
methyldopa, Inflammation, Blindness	Altered Intercellular Communication	AMD, the leading cause of irreversible blindness among the elderly, involves many genetic and environmental risk factors, including oxidative stress and inflammation.	21042291
Inflammation	Altered Intercellular Communication	Growth-regulated oncogene a (GROa) is a chemokine that plays a role not only in inflammation, but also in tumorigenesis.	21042742
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Recent studies have demonstrated aberrant CpG island methylation (CIM) in chronic inflammation, aging and cancer.	21042749
Inflammation, Non-alcoholic Fatty Liver Disease, Fatty degeneration	Altered Intercellular Communication	The pathological role of visceral fat accumulation in steatosis, inflammation, and progression of nonalcoholic fatty liver disease.	21042922
Inflammation, Comorbidity	Altered Intercellular Communication	The basis of this relationship with survival is not known; however, systemic inflammation may reflect comorbidity.	21042941
Inflammation, Amyloidosis, Periodontal Diseases	Altered Intercellular Communication	Interaction between periodontal disease and systemic secondary amyloidosis: from inflammation to amyloidosis.	21043797
Inflammation, Periodontal Diseases	Altered Intercellular Communication	It has become increasingly clear in recent years that periodontal disease can cause a dramatic increase in the levels of markers of systemic inflammation, and that periodontal treatment can result in reduction in the levels of these markers.	21043797
Inflammation, Myocardial Reperfusion Injury	Altered Intercellular Communication	TLR4 has been shown to mediate inflammation in animal models of myocardial ischemia/reperfusion injury (MI/RI).	21044745
Inflammation, Atherosclerosis	Altered Intercellular Communication	Adipo-(cyto)kines are associated with insulin resistance, atherosclerosis and inflammation.	21044750
Inflammation, Specimen Source Codes - Abscess	Altered Intercellular Communication	But no evidence of aortic or leaflet vegetations suggesting for abscess was found, neither atheromatous or calcified plaques, nor signs of inflammation of the aortic wall were detected.	21044971
Inflammation, Perforation (observation), Tuberculosis, Malignant Childhood Neoplasm, Typhoid Fever	Altered Intercellular Communication	The most common cause of non-traumatic perforation of small intestine was typhoid (46.4%), followed by non-specific inflammation (39.2%), tuberculosis (12.8%) and malignant neoplasm (1.6%).	21045358
Proximal tubulopathy	Altered Intercellular Communication	Biopsies showed varying degrees of tubulointerstitial inflammation, viral inclusions and evidence of tubular damage.	21045390
Cytomegalovirus	Altered Intercellular Communication	Histological features of PVN involving the kidneys have considerable morphological overlap with acute rejection while CMV disease presents primarily as tubulointerstitial inflammation.	21045390
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	All biopsies were evaluated for fibrosis, inflammation, and steatosis.	21046172
Hepatic inflammation, Hepatitis C	Altered Intercellular Communication	Metabolic factors, as well as sex and hepatic inflammation, are independent risk factors for serum ALT elevation in hepatitis C virus (HCV)-infected patients.	21046172
Sea Level Rise	Altered Intercellular Communication	The CEA-level, however, was within normal range and there was no evidence of hormonal overproduction.	21046476
Inflammation, VWF wt Allele	Altered Intercellular Communication	VWD is caused by a defect or deficiency in von Willebrand factor (VWF), a glycoprotein essential for normal hemostasis that is involved in inflammation.	21048155
Inflammation, destruction joint	Altered Intercellular Communication	Because mechanism for inhibition of inflammation or joint destruction might be independent, we should investigate further the relationship between inflammation and joint destruction in the future.	21048388
Inflammation, Coronary Artery Disease, Inflammatory disorder, Atherosclerosis	Altered Intercellular Communication	Since atherosclerosis may in part be an inflammatory disease, circulatory factors related to inflammation may be predictors of coronary artery disease.	21048807
Autoimmune Chronic Hepatitis, Insemination, Artificial, Homologous	Altered Intercellular Communication	Autoimmune hepatitis (AIH) is a chronic inflammatory condition of the liver of unknown etiology.	21049414
Intestinal metaplasia, Inflammation, Gland, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Receiver operating characteristic (ROC) curve analysis showed that the sensitivity and specificity of CLE were 82.9% and 90.9% for the diagnosis of H. pylori infection, 94.6% and 97.4% for predicting gastric normal mucosa, 98.5% and 94.6% for predicting histological active inflammation, 92.9% and 95.2% for predicting glandular atrophy, 98.6% and 100% for diagnosing intestinal metaplasia, respectively.	21049554
Inflammation, Infestation, Demodex Mite	Altered Intercellular Communication	Infestation of Demodex mites induces change of tear cytokine levels, IL-17 especially, which cause inflammation of the lid margin and ocular surface.	21050771
Stomatitis, Atrophy of corpus callosum	Altered Intercellular Communication	The presence of dupA was also associated with an increased degree of antral mucosa inflammation (p=0.01) and with decreased corpus atrophy (p<0.01) as well as with increased gastric mucosa IL-8 levels (p=0.04).	21050811
Airway structure, Asthma	Altered Intercellular Communication	However, no biomarker of airways inflammation has been included in the assessment of asthma control.	21051211
Inflammation, Postoperative infection	Altered Intercellular Communication	During the surgical procedure, primary implant placement was successfully completed, and any postoperative infection or inflammation rapidly resolved in all 27 patients (29 eyes).	21052507
Communicable Diseases, Endophthalmitis, CTCAE, Inflammation	Altered Intercellular Communication	Evisceration with primary porous implant placement as the treatment for recalcitrant endophthalmitis resulted in rapid resolution of any infection and inflammation.	21052507
Inflammation, Traumatic injury	Altered Intercellular Communication	A previously healthy 50-year-old man was transferred to our hospital for evaluation of acute inflammation in his right eye after ocular trauma while using a grass mower.	21052515
Inflammation, Restenosis	Altered Intercellular Communication	Inflammation may play a pivotal role in LASM just as it plays in stent restenosis.	21052690
Intraocular inflammation, Sarcoidosis, Uveitis	Altered Intercellular Communication	Ninety-seven sarcoidosis patients with intraocular inflammation diagnosed at the Uveitis Clinic of Tokyo Medical University Hospital between 1997 and 2006 were analyzed retrospectively.	21052899
Aphthous Stomatitis, Intestines, Chronic inflammation	Altered Intercellular Communication	Biopsy of the intestinal lesions revealed chronic inflammation, aphthous ulcers and microgranulomas, favoring a diagnosis of CD.	21053593
Irritation - emotion, Inflammation	Altered Intercellular Communication	Microleakage can cause pulpal irritation and periapical inflammation.	21053643
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	An adequate range of colonic observations for precise evaluation of inflammation in ulcerative colitis (UC) patients has not been reported.	21054518
Inflammation	Altered Intercellular Communication	The colonic site with maximum inflammation was determined for each patient.	21054518
Inflammation	Altered Intercellular Communication	Of 545 patients, 319 (59%) had maximum inflammation in the rectum, 79 (14%) in the sigmoid colon, 70 (13%) in the descending colon, and 77 (14%) on the oral side of the splenic flexure.	21054518
Inflammation	Altered Intercellular Communication	Moreover, among 134 patients with no inflammation in the rectum and sigmoid colon, 54 (40%) had inflamed mucosa in the descending colon or the more proximal portion.	21054518
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Sigmoidoscopy is not sufficient for evaluating inflammation in UC patients.	21054518
Inflammation, Cardiac complication, Chronic Kidney Diseases	Altered Intercellular Communication	Low-grade systemic inflammation, oxidative stress and peripheral insulin resistance are intimately associated and contribute to the increased risk of cardiovascular complications in advanced chronic kidney disease (CKD).	21054584
Albuminuria	Altered Intercellular Communication	Inflammation gene variants and susceptibility to albuminuria in the U.S. population: analysis in the Third National Health and Nutrition Examination Survey (NHANES III), 1991-1994.	21054877
Inflammation	Altered Intercellular Communication	While the underlying etiology is unclear, chronic, low-grade inflammation is a suspected key factor.	21054877
Albuminuria	Altered Intercellular Communication	Our findings suggest a small role for genetic variation within inflammation-related genes to the susceptibility to albuminuria.	21054877
Inflammation, Kidney damage	Altered Intercellular Communication	Additional studies are needed to further assess whether genetic variation in these, and untested, inflammation genes alter the susceptibility to kidney damage.	21054877
Inflammation, Peripheral T-Cell Lymphoma, B-Cell Lymphomas	Altered Intercellular Communication	The control cases included 18 cases of peripheral T-cell lymphoma, 10 cases of B-cell lymphoma, 5 cases of normal spleen, 5 cases of normal thymus and 10 cases of nasal mucosal tissues affected by chronic inflammation.	21055151
Granulomatous inflammation	Altered Intercellular Communication	The diagnosis was supported by detection of granulomatous inflammation in a laryngeal biopsy.	21055382
Inflammation, Neoplasms, Nephrolithiasis	Altered Intercellular Communication	Chronic inflammation and renal lithiasis seem to be associated with this tumour.	21055527
Inflammation, Fibrosis Assessment, Primary malignant neoplasm	Altered Intercellular Communication	Circulating levels of YKL-40 are related to the degree of inflammation, tissue remodeling, fibrosis, and cancer progression.	21055651
Inflammation, Congestive heart failure	Altered Intercellular Communication	Serum YKL-40, a new marker of inflammation, was increased in CHF, and YKL-40 detected high risk patients for adverse outcomes in CHF.	21055651
Inflammation, Peri-Implantitis	Altered Intercellular Communication	We concluded that in the presence of peri-implant inflammation, bone quantity and characteristics may influence the progression of peri-implantitis bone loss at dental implants.	21055752
Inflammation, Peri-Implantitis	Altered Intercellular Communication	To achieve an understanding of the local degradation of bone due to peri-implantitis, we need to analyze the microstructure of the bone as well the cellular biology of the peri-implant inflammation.	21055752
Refractory anemias, Inflammation	Altered Intercellular Communication	SF Th1 percentages directly correlated with inflammation and disease activity (CRP, swollen joint count [SJC]) indices in SpA, but not in RA patients.	21056009
Inflammation, Esthesia, Swelling, Back Pain, Arthritis	Altered Intercellular Communication	Self-reported arthritis-related illness was indicated by the presence of arthritis, back and joint pain, biting sensation, swelling and inflammation in the joints.	21056439
Delirium	Altered Intercellular Communication	Impaired cholinergic neurotransmission seems to have an important role in the development of delirium.	21056464
Inflammation, Hypertrophy	Altered Intercellular Communication	Mice deficient in MMP-9 develop the same degree of cigarette smoke-induced inflammation and airspace enlargement as strain-matched controls.	21057003
Inflammatory Bowel Diseases	Altered Intercellular Communication	Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the gastrointestinal tract.	21057150
Inflammation, Communicable Diseases, Fibrosis Assessment, Bipolar Disorder, Fatigue	Altered Intercellular Communication	Clinical parameters including infection activity, fibrosis stage or inflammation grade, as well as depressive symptoms and fatigue were found to be significantly associated with HRQOL.	21057161
Inflammatory abnormality of the eye	Altered Intercellular Communication	The ocular inflammation subsided gradually and her BCVA returned to normal after intensive steroid treatment.	21057804
Metabolic Diseases, Atherosclerosis	Altered Intercellular Communication	Osteocalcin, a bone-derived polypeptide, was recently found to have hormonal function associated with metabolic disorders and atherosclerosis.	21059437
Cerebrovascular, Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a pivotal role in the pathogenesis of atherosclerosis and of cerebrovascular complications.	21059542
Inflammation	Altered Intercellular Communication	Transforming growth factor-b (TGF-b) is a pleiotropic cytokine with a central role in inflammation.	21059542
Inflammation, Seizures, Encephalitis, Hallucinations, Agitation, Irritable Mood, Thinking, function, Psychiatric, Bacterial Infections	Altered Intercellular Communication	These included encephalitic signs with psychiatric symptoms (agitation, paranoid thoughts, irritability, or hallucinations); seizures; CSF inflammation; and exclusion of viral or bacterial infection.	21060097
Intraocular inflammation	Altered Intercellular Communication	Two patients developed intraocular inflammation with high intraocular pressure 3 and 5 weeks after the infliximab injection, respectively.	21060271
Intraocular inflammation	Altered Intercellular Communication	In addition, half of the cases developed intraocular inflammation.	21060271
Inflammation, Obesity	Altered Intercellular Communication	Age, sex, and ethnicity may modify the influence of obesity on inflammation.	21060285
Inflammation, Obesity	Altered Intercellular Communication	Many medical concerns associated with obesity are due to chronic inflammation, but factors underlying the development or maintenance of obesity-associated inflammation remain unclear.	21060285
Inflammation, Obesity	Altered Intercellular Communication	This study investigated how age, sex, and ethnicity may modify the interplay of subclinical inflammation and obesity in nationally representative contexts.	21060285
Inflammation, Obesity	Altered Intercellular Communication	Factors, such as age, sex, and ethnicity, may modify the influence of obesity on subclinical inflammation at the population level.	21060285
Optic Neuritis	Altered Intercellular Communication	TGF-b1 induces an age-dependent inflammation of nerve ganglia and fibroplasia in the prostate gland stroma of a novel transgenic mouse.	21060787
Prostate carcinoma	Altered Intercellular Communication	The novel findings of ganglia and vessel inflammation associated with formation of collagenous micronodules in collapsed acini is important as each of these are observed in human prostate carcinoma and may play a role in disease progression.	21060787
Inflammation, Hodgkin Disease	Altered Intercellular Communication	Hodgkin disease risk: role of genetic polymorphisms and gene-gene interactions in inflammation pathway genes.	21061265
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation is a critical component of cancer development.	21061265
HD Term Type, Inflammation	Altered Intercellular Communication	Our study is the first to report the association between polymorphisms in inflammation genes and HD susceptibility risk.	21061265
Inflammation, Atherosclerosis	Altered Intercellular Communication	Invariant natural killer T cells: linking inflammation and neovascularization in human atherosclerosis.	21061446
Rupture	Altered Intercellular Communication	Inflammation participates in lesion progression and plaque rupture.	21061446
Watery diarrhea, Fever, CTCAE	Altered Intercellular Communication	A 73-year-old Japanese male was admitted because of difficulty in standing up after acute upper respiratory inflammation with mild fever followed by watery diarrhea.	21061550
Inflammation, Fibrosis Assessment, Myocarditis, CTCAE 5.0, Ischemia	Altered Intercellular Communication	Conversely, fat replacement without fibrosis may be seen secondary to infectious myocarditis, chronic inflammation, and ischemia and as part of the aging process.	21062175
Pain Distress Question, Inflammation	Altered Intercellular Communication	Salicylates have been used since antiquity to relieve pain and inflammation.	21062358
Amyotrophic Lateral Sclerosis, Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	The contribution of inflammation to neurodegenerative diseases is increasingly recognized, but the role of inflammation in sporadic amyotrophic lateral sclerosis (sALS) is not well understood and no animal model is available.	21062492
Inflammation	Altered Intercellular Communication	Aggregated wild type SOD-1 in sALS neurons could induce in mononuclear cells the cytokines inducing chronic inflammation in sALS spinal cord, in particular IL-6 and IL-17A, damaging neurons.	21062492
Inflammation	Altered Intercellular Communication	Immune modulation of chronic inflammation may be a new approach to sALS.	21062492
Carcinoma of lung	Altered Intercellular Communication	Hormonal and EGFR pathways together may contribute to lung cancer prognosis.	21062926
Acute Coronary Syndrome, vascular inflammations, Dental Plaque, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Vascular inflammation can lead to plaque instability and acute coronary syndromes (ACS).	21062996
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	We are led to conclude that inflammation that occurs locally in epicardial adipose tissue of CAD contributes to the pathogenesis of coronary artery disease.	21063839
Inflammation, Hepatitis B	Altered Intercellular Communication	Hepatitis B is inflammation of the liver caused by a Hepatitis B virus, having a parenteral mode of entry and infecting millions of people around the world.	21067032
Seroma, Fibrosis Assessment, Inflammation, Neoplasms	Altered Intercellular Communication	DCE-MRI differentiated the rapidly enhancing recurrences, residual tumors and metastases from the slowly enhancing inflammation, and the non-enhancing seromas and fibrosis.	21067882
Communicable Diseases, Fracture, Osteoporosis, Myositis	Altered Intercellular Communication	RadRx further predisposed post-resection and post-ECRRI patients to develop fractures, osteoporosis and infection and was the major cause of persistent muscle inflammation at MRI.	21067882
Inflammation, Rheumatoid Factor, Synovitis	Altered Intercellular Communication	On an individual level, USGS inflammation, MRI synovitis and MRI BME also somewhat better predicted outcome than rheumatoid factor, anticitrullinated protein antibodies and disease activity score 28.	21068093
Refractory anemias, Inflammation	Altered Intercellular Communication	USGS inflammation and MRI BME were independent predictors of MRI erosive progression in early RA patients on a group level.	21068093
Inflammation	Altered Intercellular Communication	Greater variety in fruit and vegetable intake is associated with lower inflammation in Puerto Rican adults.	21068354
Inflammation	Altered Intercellular Communication	FV variety, but not quantity, appears to be important in reducing inflammation.	21068354
Inflammation, Epstein-Barr Virus Infections, Neurologic Symptoms	Altered Intercellular Communication	Primary EBV infections in immune competent persons can cause a broad range of neurological symptoms, with lymphocytic and monocytic inflammation both in blood and CSF.	21070089
Communicable Diseases, Inflammation	Altered Intercellular Communication	Among 16 patients presenting with preerosion associated with signs of local cutaneous inflammation, 62.5% developed an infection of the pacing system requiring later explantation.	21070257
Inflammation	Altered Intercellular Communication	Extensive, previous evidence (reviewed here) indicates an important role for noradrenaline in the control of inflammation in the brain.	21070631
Inflammation, Data types - Address	Altered Intercellular Communication	Thus, the -1021T allele with presumed low activity may be associated with misregulation of inflammation, which could contribute to the onset of AD.	21070631
Inflammation, Dysphonia, Posterior rhinorrhea	Altered Intercellular Communication	The common findings of the upper respiratory tract were dysphonia (79.1%), post-nasal discharge (PND; 41.9%), lower larynx position (30.2%), limitation of vocal cords (25.6%) and mucosal inflammation of larynx (14.8%).	21071549
Inflammation, Restenosis, Atherosclerosis	Altered Intercellular Communication	Resistin is an adipocytokine that may link inflammation and atherosclerosis.We studied the associations of resistin levels with cardiovascular events and restenosis.	21071880
Inflammation	Altered Intercellular Communication	Grade of inflammation was rated according to the updated Sydney Scoring System.	21073375
Inflammation, Gastritis	Altered Intercellular Communication	Gastritis was classified as corpus-predominant when the degree of chronic inflammation was higher in the corpus than in the antrum and vice versa for antrum-predominant gastritis.	21073375
Inflammation, Dental Plaque	Altered Intercellular Communication	In addition FABP4/aP2 correlates with other important signs of inflammation and plaque instability, such as T cells and leukotriene enzymes.	21073559
Inflammation	Altered Intercellular Communication	Taken together, these results indicate that FABP4/aP2 is a key factor connecting vascular and cellular lipid accumulation to inflammation.	21073559
Inflammation	Altered Intercellular Communication	In patients with a DU, moderate-severe chronic inflammation at the lesser and greater curvatures of corpus was associated with GC risk (OR, 3.70; 95% CI, 1.46-9.36, and OR, 7.72; 95% CI, 3.18-18.7, respectively).	21073608
Inflammation, PDR gene	Altered Intercellular Communication	Further studies are needed to provide better understanding of IL-8 and inflammation involvement in visual prognosis in PDR.	21073666
Intraocular inflammation, Lesion of retina	Altered Intercellular Communication	In 15 eyes (75%) the retinal lesions were associated with intraocular inflammation.	21074095
Inflammation, Fracture	Altered Intercellular Communication	The abundance of a selection of transcript species involved in inflammation, immunosenescence and stress response was compared between PBMC of 35 geriatric patients with hip fracture in acute phase (days 2-4 after hospitalization) or convalescence phase (days 7-10) and 28 healthy aged controls.	21074600
Inflammation, Fibrosis Assessment, Abnormally opaque structure (morphologic abnormality)	Altered Intercellular Communication	Lung computed tomography showed diffuse centrilobular nodules and branching linear opacities, whereas lung biopsy demonstrated diffuse peribronchiolar fibrosis and chronic inflammation with bronchiolectasis.	21074694
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) as inflammation markers in elderly patients with stable chronic obstructive pulmonary disease (COPD).	21074870
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Erythrocyte sedimentation rate (ESR) might represent a less expensive alternative to C-reactive protein (CRP) as a marker of systemic inflammation in stable chronic obstructive pulmonary disease (COPD).	21074870
Gastrointestinal inflammation, Colitis	Altered Intercellular Communication	Thirty-three patients (7.1%) reported serious AEs; one patient's severe gastrointestinal inflammation and colitis were considered possibly study drug-related.	21075272
Hemorrhagic Fevers, Viral, Acute inflammation, Hemorrhagic Fever with Renal Syndrome, Syndrome	Altered Intercellular Communication	This report describes a rare clinical manifestation of hemorrhagic fever with renal syndrome (HFRS), and shows that HFRS might be difficult to diagnose especially when symptoms mimick those of an acute abdominal inflammation.	21075678
Inflammation	Altered Intercellular Communication	The greatest impact on this result had early adverse events as insufficient closure, wound incrustation, and inflammation (9.3 vs. 6.0%; P = 0.02).	21075757
Inflammation, Heart failure	Altered Intercellular Communication	Cardiac inflammation contributes to changes in the extracellular matrix in patients with heart failure and normal ejection fraction.	21075869
Inflammation	Altered Intercellular Communication	Here we report the influence of cardiac inflammation on extracellular matrix (ECM) remodeling in patients with HFNEF.	21075869
Diastolic dysfunction, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	A positive correlation between cardiac collagen, as well as the amount of inflammatory cells, and diastolic dysfunction was evident and suggests a direct influence of inflammation on fibrosis triggering diastolic dysfunction.	21075869
Diastolic dysfunction, Inflammation	Altered Intercellular Communication	Cardiac inflammation contributes to diastolic dysfunction in HFNEF by triggering the accumulation of ECM.	21075869
Inflammation	Altered Intercellular Communication	Epitope 4 includes the interaction site between sEPCR and PR3 which may serve as an important interaction to down-regulate inflammation.	21077276
Communicable Diseases, Inflammation	Altered Intercellular Communication	Nevertheless the disease may recur in the inguinal areas and frequently be lethal, therefore close surveillance and early attempts to treat the recurrent disease before infection and inflammation ensues should be the aim of current treatment strategies.	21077489
Refractory anemias, Rheumatoid Arthritis, Inflammation, Physical disability	Altered Intercellular Communication	To determine whether low-dose prednisolone affects body composition and bone mineral density (BMD) in patients with rheumatoid arthritis (RA), also considering inflammation and physical disability.	21077801
Refractory anemias, Inflammation, Federated States of Micronesia	Altered Intercellular Communication	RA patients treated with low-dose prednisolone had significantly higher FM than patients without prednisolone, an effect that was independent of current inflammation.	21077801
Gastrointestinal inflammation	Altered Intercellular Communication	Selective inhibition of IFN-g mediated apoptosis, while preserving its beneficial consequences on the ratio of IL-18/IL-18bp, could contribute to the integrity of the mucosal barrier in intestinal inflammation.	21078084
Inflammation, Crohn Disease	Altered Intercellular Communication	Low-dose (18)F-FDG PET/CTE, compared with CTE, may improve the detection and grading of active inflammation in patients with Crohn disease.	21078803
Orosomucoid, Inflammation, Buccal Route of Drug Administration	Altered Intercellular Communication	Bone loss was observed buccally and was more pronounced in patients with GAgP, with a significant correlation with keratinized mucosa and increased inflammation.	21080785
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	There is growing evidence that inflammation is a causal factor in cancer, where pro-inflammatory cytokines such as IL-6, IL-1 or TNF-a could induce cellular proliferation by activation of NF-kB.	21081304
Colorectal Carcinoma, Obesity	Altered Intercellular Communication	Our study supports the concept that obesity-related inflammation, rather than obesity itself, is associated with colorectal cancer progression and survival.	21081932
Inflammation, Liver damage	Altered Intercellular Communication	Two of the upregulated genes, LCN2 and IQGAP1, have been previously linked to inflammation in smokers and response/repair to cellular injury in bronchial epithelium.	21082746
Presenile dementia, Inflammation	Altered Intercellular Communication	Few cross-sectional studies and some longitudinal studies have attempted to link oral health with dementia diagnosis or disease pathology but none has investigated the role of inflammation as a potential mediator.	21083740
Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	After adjusting for age, significant differences were found between patients and controls with respect to gingival inflammation, dental plaque, bleeding on probing and probing pocket depth.	21083740
Inflammation, Meibomian gland dysfunction	Altered Intercellular Communication	Bacteria and chronic inflammation are contributing factors for meibomian gland disease, which leads to ocular surface and tear film alterations and chronic patient symptoms.	21083761
Inflammation	Altered Intercellular Communication	The often chronic inflammation and immune activation status in dialysis patients may accelerate tryptophan degradation, which could influence patients' psychological performance.	21084050
Inflammation, Acute myocardial infarction, Anemia	Altered Intercellular Communication	The development of anemia of inflammation during acute myocardial infarction.	21084124
Inflammation, Anemia	Altered Intercellular Communication	A pattern suggestive of anemia of inflammation including higher ferritin, lower transferring, lower transferrin saturation, and lower serum iron concentrations has been observed in anemic AMI patients ( all p<0.05).	21084124
Inflammation, Anemia	Altered Intercellular Communication	We therefore suggest the possibility that at least part of the hemoglobin drop in AMI prior to angiography is related to the anemia of inflammation.	21084124
Appendicitis, CTCAE, Intraluminal Route of Drug Administration	Altered Intercellular Communication	Computed tomography criterion for the diagnosis of appendicitis without periappendiceal inflammation in children using the maximum depth of intraluminal appendiceal fluid.	21084908
Appendicitis, CTCAE	Altered Intercellular Communication	Of 826, 192 were classified into the noncomplicated-normal appendix group (85 enlarged normal appendices [diameter >6 mm] without adjacent lesions), the complicated-normal appendix group (44 enlarged normal appendices with adjacent lesions), or the our-appendicitis group (63 operatively proved appendicitis without periappendiceal inflammation).	21084908
Appendicitis, CTCAE	Altered Intercellular Communication	The criterion "DEPTH greater than 2.6 mm" is particularly useful for differentiating appendicitis without periappendiceal inflammation from enlarged normal appendices in children.	21084908
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Regular exercise has been shown to protect against breast cancer risk, and one possible mechanism is through a reduction in inflammation.	21085036
Sepsis, Inflammation, Acute Lung Injury	Altered Intercellular Communication	Our data demonstrate the critical role of early-age-related proteostasis-imbalance as a novel mechanism that augments the NFkB mediated inflammation in sepsis and ALI.	21085581
Inflammation	Altered Intercellular Communication	Moreover, our data suggest the therapeutic efficacy of salubrinal in restraining NFkB mediated inflammation in the adult or older subjects.	21085581
Inflammation, Adenoma of lung, Interstitial Fibrosis Assessment, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Thus, lung tissue remodeling in the progression of IPF from the early to late stage of the disease comprises interrelated processes that are largely localized in the BATZ, such as immune inflammation with pathological reparation, neoangiogenesis, apoptosis, and proliferation of epitheliocytes and myofibroblasts, which lead to the development of interstitial fibrosis and adenomatosis of the lung.	21086635
Inflammation, Pancreatitis, Organ Dysfunction Scores, Infection, Cessation of life	Altered Intercellular Communication	Severe acute pancreatitis is associated with systemic inflammation, compensatory immune suppression, secondary infections, vital organ dysfunction, and death.Our study purpose was to delineate signaling profiles of circulating lymphocytes in acute pancreatitis complicated by organ dysfunction.	21087472
Pancreatitis, Acute, Inflammation, Organ Dysfunction Scores, Increase, IMMUNE SUPPRESSION	Altered Intercellular Communication	Lymphocytes of patients with acute pancreatitis, organ dysfunction and immune suppression show impaired NFkB activation, which increases infection risk and enhanced p38 activation, which sustains inflammation.	21087472
Airway structure, Inflammation, Respiratory Hypersensitivity	Altered Intercellular Communication	Common problems were: airways hyper-responsiveness (80%); airway inflammation (74%); activity limitation (74%) and systemic inflammation (60.5%).	21087988
Autoimmune Diseases, Inflammation, Neoplasms, Histopathologic Grade differentiation	Altered Intercellular Communication	B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice.	21088135
Inflammation	Altered Intercellular Communication	Accurate assessment is crucial because an intraoperative diagnosis of chronic inflammation suggestive of ALVAL will necessitate a replacement of the prosthetic component surfaces.	21088151
vascular inflammations	Altered Intercellular Communication	We thus hypothesized that treatment with atazanavir would ameliorate oxidative stress and vascular inflammation and improve endothelial function in T2DM.	21088253
Vascular Diseases, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Retroperitoneal fibrosis is an uncommon collagen vascular disease of unknown etiology, characterized by the replacement of normal retroperitoneal tissue with fibrosis and/or chronic inflammation usually surrounding the abdominal aorta and the iliac arteries and extending into adjacent anatomic structures.	21088348
Inflammation, Traumatic injury, Malignant Neoplasms, FAM126A gene, Liver Cirrhosis	Altered Intercellular Communication	Unlike most of the other malignancies, HCC almost entirely develops in the context of inflammation and organ injury and is related to cirrhosis in about 85% of the cases.	21088408
Nonalcoholic Steatohepatitis, Inflammation, Heart failure, Chronic Kidney Diseases	Altered Intercellular Communication	chronic renal disease, non-alcoholic steatohepatitis, heart failure or sclerosis) and malignant progression (and likely by reducing TGFb-regulated inflammation and immune responses -inflamm-aging-), molecularly behaves as a bona fide anti-aging modality.	21088486
Nonalcoholic Steatohepatitis, Inflammation, Heart failure, Chronic Kidney Diseases	Altered Intercellular Communication	chronic renal disease, non-alcoholic steatohepatitis, heart failure or sclerosis) and malignant progression (and likely by reducing TGFb-regulated inflammation and immune responses -inflamm-aging-), molecularly behaves as a bona fide anti-aging modality.	21088486
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	The obtained data allows assuming the important role of the IL6 and IL10 genes which are responsible for functioning of inflammation system, in the accelerated formation of failures at the patients who had a coronary syndrome.	21090240
Trachoma , Inflammation, Tissue Factor	Altered Intercellular Communication	Only 3 children were identified with active trachoma (trachoma with follicles, TF = 1; trachoma with intense inflammation, TI = 2) giving regional prevalence of 0.01% (Confidence Limits, CL: 0.0-0.1) for TF and 0.03% (CL: 0.0-0.1) for TI.	21090908
Inflammation, Hypertensive Retinopathy	Altered Intercellular Communication	The association of low-grade systemic inflammation with hypertensive retinopathy.	21091359
Inflammation, Retinal Diseases	Altered Intercellular Communication	Elevated blood pressure (BP) alone does not fully account for the extent of retinopathy, other pathogenic mechanisms may be involved, such as low-grade inflammation.	21091359
Tissue damage, Inflammation, Pathology	Altered Intercellular Communication	Cardiopulmonary bypass (CPB) causes alterations in the levels of biomarkers related to inflammation, tissue damage, and other tissue pathologies.	21092041
Tissue damage, Inflammation	Altered Intercellular Communication	Early and accurate evaluation of inflammation and tissue damage would therefore be clinically useful.	21092041
Inflammation, Diabetes Mellitus, Cardiovascular Diseases	Altered Intercellular Communication	Compared with abstainers, alcohol consumption was associated with a decreased risk of having diabetes mellitus in women (OR: 0.41, 95%CI: 0.22-0.78) after controlling for socio-demographic factors, physical activity, smoking, family income, family history of cardiovascular disease or diabetes, macronutrients intake, body mass index, and markers of inflammation and adipokines.	21092093
Inflammation	Altered Intercellular Communication	For each case, systemic and local antibiotics did not control corneal thinning, which seemed correlated with the intensity of the systematically associated signs of scleral inflammation.	21093102
Inflammation, Malnutrition	Altered Intercellular Communication	Handgrip strength as a simple indicator of possible malnutrition and inflammation in men and women on maintenance hemodialysis.	21093287
Inflammation, Malnutrition	Altered Intercellular Communication	These results suggest that HGS is a valid screening instrument for malnutrition and inflammation in patients on MHD.	21093287
Old age, Inflammation	Altered Intercellular Communication	Angiotensin II (Ang II) promotes inflammation and the generation of reactive oxygen species and governs onset and progression of vascular senescence, which are all associated with functional and structural changes, contributing to age-related diseases.	21093722
Hypotension, Orthostatic, Gastrointestinal dysmotility, Anhidrosis	Altered Intercellular Communication	Autoantibodies that impair synaptic transmission in the autonomic ganglia may cause orthostatic hypotension, gastrointestinal dysmotility, and sudomotor dysfunction.	21093734
Gastrointestinal inflammation, Obesity	Altered Intercellular Communication	Based on animal studies, RELMb is induced by high fat diets, obesity, and intestinal microflora and may play a role in insulin resistance and intestinal inflammation.	21094111
Irritation - emotion, Inflammation	Altered Intercellular Communication	The etiology is still unknown; however, SP is considered a consequence of chronic irritation and inflammation.	21094868
Pyelonephritis, Nephritis	Altered Intercellular Communication	Xanthogranulomatous pyelonephritis is a chronic renal inflammation characterized by destruction and replacement of its parenchyma with granulomatous tissue.	21094988
Inflammation	Altered Intercellular Communication	Low-grade chronic inflammation is an important risk factor for age-related morbidity.	21097658
Inflammation	Altered Intercellular Communication	Health behaviors, including average aggregate measures of sleep, have been linked to increased inflammation in older adults.	21097658
Inflammation	Altered Intercellular Communication	Variability in sleep timing may also be associated with increased inflammation.	21097658
Inflammation, Thrombosis	Altered Intercellular Communication	The remaining patient showed glomerular inflammation and thrombosis, with diffuse C4d glomerular and peritubular capillary deposition, and hypermutated V region genes.	21097789
Inflammation	Altered Intercellular Communication	Systemic inflammation was not associated with erosive activity.	21097802
Inflammation, Acute myocardial infarction, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Gene variants that promote inflammation and cholesterol metabolism have been associated with acute myocardial infarction (AMI) and Alzheimer's disease (AD).	21098980
Inflammation, Data types - Address	Altered Intercellular Communication	We conclude that AMI and AD share genetic backgrounds involving cholesterol metabolism and the upregulation of inflammation and that gene-gene interactions in relevant sets of genes may be useful in defining inherited risk for common disorders.	21098980
Airway structure, Asthma	Altered Intercellular Communication	Our data suggest that eNO level inversely correlates with small airway narrowing, and airway inflammation has a significant effect on small airway lung function in asthmatic school children.	21099248
Inflammation, Asthma	Altered Intercellular Communication	Saliva has recently been validated as novel, simple, and noninvasive method for investigating inflammation in patients with asthma.	21099251
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Histopathologically, sections of the iridectomy specimen showed a zonal granulomatous inflammation with a central iris necrotic abscess surrounded by a mantle of epithelioid histiocytes and more peripherally by lymphocytes and plasma cells.	21099401
Fibrosis Assessment, Hypertrophy	Altered Intercellular Communication	Recent studies showed that fibrosis in LF hypertrophy was due to accumulation of inflammation-related scar tissue.	21102276
Inflammation	Altered Intercellular Communication	MRI can detect active inflammation and structural damage associated with SpA.	21102381
Communicable Diseases, Inflammation	Altered Intercellular Communication	We defined iron deficiency according to the presence of malarial infection and evidence of inflammation.	21103365
Muscle Contraction, Inflammation	Altered Intercellular Communication	The results suggest that SLT induces prominent increases in CBT and IT returning to baseline thickness in a month, which may be caused by inflammation, vascular engorgement, or mechanical muscular contraction.	21104268
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Obesity and insulin resistance are characterized by a chronic and low grade state of inflammation and the pro-inflammatory response of monocytes is affected in type 2 diabetes mellitus (T2D).	21104588
Cardiovascular Diseases, Atherosclerotic lesion, Atherosclerosis	Altered Intercellular Communication	We randomly selected 411 of 1268 participants with pre-existent cardiovascular disease from the prospective Inflammation in Carotid Arteries Risk for Arthrosclerosis Study (ICARAS) and assessed their OPGs for the presence of calcified atherosclerotic lesions or indirect signs of atherosclerosis, such as surgical clips or intravascular stents.	21104618
Inflammation, Muscle damage	Altered Intercellular Communication	Quality of life, inflammation, muscle damage and disease activity scores remained unchanged.	21106107
Orbital Pseudotumor, Diabetes Mellitus	Altered Intercellular Communication	Two male adults were admitted because of newly diagnosed diabetes with hyperglycemic hyperosmolar state and CT scan showed extensive pansinusitis and orbital inflammation.	21106269
Inflammation, Cardiac Arrhythmia, Ischemia	Altered Intercellular Communication	Cardiac risk factors, left ventricular ejection fraction (LVEF), medical therapy, inflammation status, and perioperative ischemia in relation to arrhythmia were noted in all patients.	21106322
Inflammation	Altered Intercellular Communication	Successful ablation of AF, with sinus rhythm restoration and maintenance, is associated with decreased serum levels of markers of inflammation.	21106468
Cessation of life, Inflammation, Primary malignant neoplasm, Cardiovascular Diseases	Altered Intercellular Communication	Simple indices of inflammation as predictors of death from cancer or cardiovascular disease in a prospective cohort after two decades of follow-up.	21106505
Inflammation, Primary malignant neoplasm, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Previous studies have identified sub-clinical inflammation as a potential factor in the pathogenesis of cancer and cardiovascular disease (CVD) but the possibility that simple, readily measured indices of sub-clinical inflammation might predict both CVD and cancer has not been tested in the context of a single, prospective analysis.	21106505
Cessation of life, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	To evaluate simply measured indices of inflammation as long-term predictors of death from either cancer or CVD.	21106505
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The inflammation score predicted both cancer mortality (1.35, P = 0.003) and CVD mortality (1.46, P = 0.002).	21106505
Inflammation, Primary malignant neoplasm, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	Risks associated with high inflammation score were equivalent to and independent of smoking cigarettes for cancer or, for CVD, having a serum cholesterol concentration >=6.2 mmol/l.	21106505
Cessation of life, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Simple indices of inflammation predict death from cancer or CVD two decades later as strongly as smoking predicts cancer or cholesterol predicts CVD.	21106505
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Activation of adipose tissue macrophages with concomitant low-grade inflammation is believed to play a central role in the development of type 2 diabetes.	21106861
Inflammation	Altered Intercellular Communication	Reporter and chromatin immunoprecipitation assays identified a previously unrecognized nuclear factor-kB (NF-kB) response element in the TERT promoter, to which NF-kB is recruited during inflammation.	21106948
Superficial ulcer, Inflammation, Cardiac polyp, Ulcer, Foveolar hyperplasia	Altered Intercellular Communication	We then reviewed the slides of 330 adult patients diagnosed with a cardiac polyp and used semiquantitative or qualitative scales to score foveolar hyperplasia, inflammation, erosion or ulcers, epithelial type, and metaplasia.	21107084
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Chronic inflammation, fibrosis of the transverse carpal ligament (TCL), and altered sensory response contribute to the symptoms.	21107196
Inflammation, Fibrosis Assessment, Neuralgia, Carpal Tunnel Syndrome	Altered Intercellular Communication	Because substance P (SP) is known to be involved in neuropathic pain, chronic inflammation, and fibrosis, the present study evaluated changes in SP levels in patients with CTS.	21107196
Pain Distress Question, Inflammation, Carpal Tunnel Syndrome	Altered Intercellular Communication	These findings suggest that SP contributes to the pain and inflammation associated with CTS.	21107196
Inflammation, Chronic periaortitis	Altered Intercellular Communication	Recent studies have suggested that IgG4-related inflammation may play a role in chronic periaortitis.	21107232
Inflammation, Systemic disease	Altered Intercellular Communication	These pathologic conditions might represent a systemic disorder with fibrotic reaction rather than local inflammation.	21107232
Inflammation	Altered Intercellular Communication	All four cases were diagnosed with right-sided endplate inflammation and administered intradiscal steroid injections with a non-steroidal anti-inflammatory drug (NSAID).	21107557
Granulomatous inflammation, Malignant Neoplasms	Altered Intercellular Communication	Surprisingly, the CT-guided fine needle biopsy revealed no malignancy, but granulomatous inflammation and epitheloid cells.	21108184
Inflammation	Altered Intercellular Communication	Low grade inflammation, with elevated CRP and elevated fibrinogen might contribute.	21108190
Inflammation	Altered Intercellular Communication	The common risk factor is smoking; active "dentogenic" inflammation should be checked before surgery, particularly before surgery with implants.	21108190
Chronic sinusitis, inflammation or infection	Altered Intercellular Communication	Moreover, anaerobic bacteria were responsible for infectious inflammation in 66.7% of the cases with the odontogenic form of chronic sinusitis.	21108501
Scleral thickening, Inflammation	Altered Intercellular Communication	It is characterized with peripheral thickening and opacification of the stroma adjacent to the site of inflammation.	21108616
Inflammation	Altered Intercellular Communication	Changes in expression of membrane TNF, NF-{kappa}B activation and neutrophil apoptosis during active and resolved inflammation.	21109521
Exophthalmos, Orbital Pseudotumor	Altered Intercellular Communication	An eight-year-old female presented with symptoms and signs of orbital inflammation and proptosis.	21109605
Refractory anemias, Inflammation, Renal Insufficiency	Altered Intercellular Communication	NT-proBNP level, in RA patients without co-morbidities potentially influencing this level, is correlated with age, disease activity markers of inflammation, and subclinical renal impairment.	21110214
Prostate carcinoma, Orbital Pseudotumor	Altered Intercellular Communication	Orbital inflammation after use of zoledronic acid for metastasized prostate carcinoma.	21110506
Prostate carcinoma, Orbital Pseudotumor	Altered Intercellular Communication	Report of a case of orbital inflammation after the use of zoledronic acid for metastasized prostate cancer.	21110506
Intraocular inflammation, Endophthalmitis, CTCAE	Altered Intercellular Communication	Changes in visual acuity (VA) and CMT were analyzed, as were safety considerations such as intraocular inflammation and endophthalmitis.	21110509
Inflammatory abnormality of the eye	Altered Intercellular Communication	The patient was switched to difluprednate 0.05% in an attempt to better control the ocular inflammation.	21111374
Inflammation, Hernia	Altered Intercellular Communication	At surgery, contrary to the clinical suspicion of a nonbenign lesion, granulomatous inflammation of an indirect inguinal hernia was observed.	21111459
Chronic dacryocystitis, Nasolacrimal Duct Obstruction	Altered Intercellular Communication	Chronic inflammation of nasolacrimal duct determines obstruction of the lacrimal flow and is called chronic dacryocystitis.	21112571
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	Predictive factors for body atrophy reversal at Cox-regression analysis were mild atrophy (HR 2.14; 95% CI 1.12-4.1), moderate-severe inflammation (HR 5.3; 95% CI 1.64-17.3), and absence of intestinal metaplasia (HR 2.4; 95% CI 1.2-4.8).	21112822
Refractory anemias, Inflammation	Altered Intercellular Communication	The correlation of HO-1 concentration in synovial fluid with serum CRP and MMP-3 in joint fluid indicated that HO-1 might be useful as a marker of joint inflammation in RA patients.	21113640
Inflammation, Villous atrophy, Celiac Disease, Malabsorption Syndrome, Crypt hyperplasia	Altered Intercellular Communication	Celiac disease or gluten-sensitive enteropathy is characterized by malabsorption, chronic inflammation of the small intestine mucosa, villous atrophy and crypt hyperplasia.	21113713
Inflammation, Osteoporosis, Osteoporosis, Postmenopausal, Refractory anemias, Arthritis	Altered Intercellular Communication	Here, we propose that S1P-targeted therapy is beneficial not only for limiting inflammation but for preventing bone-resorptive disorders, such as osteoporosis, by controlling the migratory behavior of osteoclast precursors and therefore would be good for treating elderly female RA patients who suffer from postmenopausal osteoporosis and arthritis simultaneously.	21113810
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide (NO), commonly accepted marker of airways inflammation, may be generated both by specific enzymes, NO synthases, as well as by nonenzymatic reduction in its metabolites.	21114492
Blood coagulation, Cerebrovascular accident	Altered Intercellular Communication	Association of coagulation-related and inflammation-related genes and factor VIIc levels with stroke: the Cardiovascular Health Study.	21114618
Inflammation, Thrombosis, Cerebrovascular accident	Altered Intercellular Communication	Thrombosis and inflammation are critical in stroke etiology, but associations of coagulation and inflammation gene variants with stroke, and particularly factor VII levels, are inconclusive.	21114618
Inflammation	Altered Intercellular Communication	Isolated glomerular accumulation of complement component 3 (C3) is typical with variable degrees of glomerular inflammation.	21114651
Inflammation, Tubulitis Assessment	Altered Intercellular Communication	Inflammation and injury-down PBTs correlated with histologic inflammation and tubulitis, and the inflammation transcripts were greater in kidneys diagnosed as T cell-mediated or borderline rejection.	21114657
Anemia	Altered Intercellular Communication	Association between the malnutrition-inflammation score and post-transplant anaemia.	21115668
Inflammation, Tumor necrosis	Altered Intercellular Communication	Biomarkers reflecting nutritional status and inflammation [serum leptin, albumin, interleukin-6 (IL-6), tumour necrosis factor-a (TNF-a) and C-reactive protein] were measured.	21115668
Inflammation	Altered Intercellular Communication	Inadequate serum 25(OH)D is associated with vascular endothelial dysfunction among healthy middle-aged/older adults, and this is mediated in part by nuclear factor kB-related inflammation.	21115878
Carcinogenesis, Hepatitis, Liver Cirrhosis	Altered Intercellular Communication	These findings have implications for understanding the evolution from liver inflammation to cirrhosis and associated carcinogenesis.	21115898
Data types - Address	Altered Intercellular Communication	These findings suggest a possible link between impaired cholinergic neurotransmitter function in AD and Ab pathogenesis.	21116052
Inflammation, Dental Plaque, Atherosclerotic lesion	Altered Intercellular Communication	Expression of IL-17A in human atherosclerotic lesions is associated with increased inflammation and plaque vulnerability.	21116822
Communicable Diseases, Inflammation	Altered Intercellular Communication	Interleukin-17A is a pivotal effector cytokine, which modulates immune cell trafficking and initiates inflammation in (auto)immune and infectious diseases.	21116822
Inflammation, Malnutrition, Chronic Kidney Diseases, Cardiovascular system	Altered Intercellular Communication	Chronic inflammation and malnutrition are associated with increased risk of cardiovascular death in individuals with chronic kidney disease.	21118362
Periodontal Diseases, Bacterial Infections	Altered Intercellular Communication	Periodontal disease is an inflammatory condition caused by bacterial infections that result in loss of the tooth supporting tissue.	21118415
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a key role in the development of atherosclerosis.	21119577
Inflammation, Vasculitis, CTCAE, Systemic Vasculitis	Altered Intercellular Communication	Microscopic polyangiitis (MPA) is an anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis characterized by inflammation of small-sized vessels.	21120499
Orthodontic, Inflammation, Superficial ulcer, Ulceration, CTCAE, Contusions	Altered Intercellular Communication	Gingival inflammation, erosion, ulceration, and contusion were the most common findings in orthodontic patients.	21121986
Gingivitis, Inflammation	Altered Intercellular Communication	The severity of gingival inflammation was in correlation with oral hygiene status; the poorer oral hygiene, the more severe gingival inflammation was.	21121986
AGA gene, Alopecia, CTCAE, Disease	Altered Intercellular Communication	Androgenetic alopecia (AGA) is a common androgen-induced progressive disorder; the pathways of which are regulated by local genetic codes and hormonal control.	21122044
TNF protein, human, Tumor necrosis, Inflammatory Bowel Diseases	Altered Intercellular Communication	Tumour necrosis factor-alpha (TNF-a) inhibitors represent an important treatment advance for a number of inflammatory conditions, including inflammatory bowel disease.	21122493
Crohn Disease, Acute inflammation	Altered Intercellular Communication	It was recently reported that disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease.	21122532
Inflammation, Hypoxia, hepcidin	Altered Intercellular Communication	The transcription of hepcidin is controlled by the iron status of the body, hypoxia, and/or inflammation.	21122575
Crohn Disease, Ulcerative Colitis	Altered Intercellular Communication	To date, only two cases of FP have been reported in patients with inflammatory conditions of the gastrointestinal tract other than ulcerative colitis or Crohn's disease.	21122579
Airway structure, cell wall thickening	Altered Intercellular Communication	The evaluation of patient showed findings of large airway inflammation with tracheal wall thickening and mucosal irregularities.	21122581
Inflammation, Hypertension, CTCAE, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Both hypertension and inflammation are major risk factors for cardiovascular disease (CVD) in HDD-CKD patients.	21124333
Inflammation, Osteopenia	Altered Intercellular Communication	TGF-b1 as possible link between loss of bone mineral density and chronic inflammation.	21124921
Chronic inflammation	Altered Intercellular Communication	However, patients with chronic inflammation, having increased TGF-b(1) serum-levels, often show reduced bone mineral content and disturbed bone healing.	21124921
Inflammation, Refractory anemias, Infection, Rheumatoid Arthritis, Amyloidosis	Altered Intercellular Communication	Systemic amyloidosis A (AA), secondary to infections and chronic inflammation, especially rheumatoid arthritis (RA), is the most common form of amyloid deposition.	21125155
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Our results suggest that GPx and CRP, as biomarkers of oxidative stress and chronic inflammation, respectively, have significant role in the pathogenesis of metabolic syndrome.	21125208
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Extraintestinal manifestations of inflammatory bowel disease occur frequently in parallel to the inflammation in the bowel.	21125512
Gastrointestinal inflammation	Altered Intercellular Communication	The activity of extraintestinal manifestations is often divergent to the activity of intestinal inflammation.	21125512
Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Overproduction of inflammation-related cytokines plays an important role in systemic lupus erythematosus (SLE).	21126942
HD Term Type, Inflammation	Altered Intercellular Communication	HD with the use of VEM resulted in a significant reduction in inflammation and oxidative stress markers.	21127134
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	They are involved in the association of chronic inflammation and cardiovascular disease in kidney patients.	21127137
Inflammatory disorder, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	This imbalance and an excess of ROS induce tissue/cellular damage, which are implicated in chronic inflammation disorders such as obesity, insulin resistance, and metabolic syndromes.	21127481
Fibrosis Assessment, Hepatitis, Hepatitis B, Chronic	Altered Intercellular Communication	Levels of serum markers of liver inflammation and fibrosis in patients with chronic hepatitis C virus infection according to HIV status and antiretroviral use.	21128862
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	In conclusion, serum markers of hepatic inflammation and fibrosis are overexpressed in HIV-HCV-coinfected patients with advanced immunosuppression, while HAART has a "protective" effect.	21128862
ARCN1 gene, Inflammation	Altered Intercellular Communication	CD4+/CD25+ cells in systemic inflammation in COPD.	21129004
ARCN1 gene, Inflammation	Altered Intercellular Communication	The results of this study support the possible role of CD4/CD25/CTLA4 cells and adiponectin in the systemic inflammation in COPD.	21129004
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Exploring multilocus associations of inflammation genes and colorectal cancer risk using hapConstructor.	21129206
Airway structure, Malignant Neoplasms	Altered Intercellular Communication	In conclusion, inflammatory conditions consistent with upper airway infection cause most acquired paediatric neck masses, but malignant neoplasms constitute a significant proportion.	21129917
Inflammation	Altered Intercellular Communication	Data have suggested a significant role of inflammation in the progression of BPH.	21130246
Inflammation, Rheumatoid Arthritis, Cardiovascular Diseases	Altered Intercellular Communication	Angiopoietin-2 is highly correlated with inflammation and disease activity in recent-onset rheumatoid arthritis and could be predictive for cardiovascular disease.	21131273
Refractory anemias, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	To investigate whether serum levels of endothelial cell activation markers in early RA patients can serve as biomarkers for inflammation and disease activity, and are associated with radiological progression and development of cardiovascular disease (CVD).	21131273
Inflammation	Altered Intercellular Communication	Markers of inflammation and disease activity were assessed, as well as radiological damage of hands and feet, at diagnosis and after 2 years.	21131273
Refractory anemias, Inflammation	Altered Intercellular Communication	Patients with RA had higher levels of VEGF and Angpt-2 at disease onset compared with healthy controls, which correlated with markers of inflammation, but were not predictive of radiological progression after 2 years.	21131273
Refractory anemias, Inflammation	Altered Intercellular Communication	In early RA, markers of endothelial activation are highly correlated with inflammation and disease activity, but not with radiological progression.	21131273
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The mucinous changes are frequently seen with chronic inflammation and/or other metaplastic changes and without cytologic evidence of malignancy.	21131836
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Systemic inflammation is associated with atrial fibrillation (AF) and inflammatory processes are involved in the pathophysiology of AF.	21132345
Anemia, Panhypopituitarism	Altered Intercellular Communication	Severe anaemia caused by panhypopituitarism shows the importance of the hormonal system for erythropoiesis.	21132394
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	NYU study supports link between gum inflammation and Alzheimer's.	21133283
Inflammation, Carcinoma	Altered Intercellular Communication	Various types of lesion from inflammation to carcinoma can affect breast.	21133590
Communicable Diseases	Altered Intercellular Communication	Neutrophil gelatinaase-associated lipocalin (NGAL) is a glycoprotein bound with matrix metalloproteinase-9 (MMP-9) in human neutrophils, and elevated tissue NGAL expression has been documented in different infectious and inflammatory conditions.	21133718
Inflammation, Periodontitis, Alveolar bone destruction	Altered Intercellular Communication	Within the limits of this study, periodontal inflammation in smoker chronic periodontitis patients seems to lower plasma osteoprotegerin levels and thereby increase the RANKL/OPG ratio, and possibly play a role in the increased susceptibility for alveolar bone destruction in smoker subjects.	21133939
Inflammation, Diverticulum	Altered Intercellular Communication	In UCD, the inflammation in colonic area harbouring diverticula always affects the overall colonic mucosa in all cases, involving also diverticular orifices.	21133960
Deficiency of butyryl-CoA dehydrogenase, Inflammation	Altered Intercellular Communication	The endoscopic characteristic of SCAD is that inflammation is mainly detected within the inter-diverticular mucosa without involvement of the diverticular orifices.	21133960
Diverticular disease of colon, Inflammation	Altered Intercellular Communication	In clinical practice, the incidence of mucosal inflammation in the presence of colonic diverticular disease is low and endoscopy is the mainstay of differential diagnosis.	21133960
Inflammation, Obesity	Altered Intercellular Communication	Low-grade inflammation is a key feature of obesity, characterized by elevated plasma levels of C-reactive protein (CRP).	21134343
Inflammation, Squamous cell carcinoma, "Marjolins ulcer", Ulcer	Altered Intercellular Communication	Squamous cell carcinomas are known to occur in ulcers of considerable duration but such rapid growth in such a short duration and rapid lymphatic spread is unusual in Marjolin's ulcer as the lymphatics are usually destroyed because of previous inflammation and scarring.	21134955
nervous system disorder, Inflammation	Altered Intercellular Communication	CXCL13 was measured by ELISA in 837 subjects: relapsing-remitting MS (RRMS; n=323), secondary progressive MS (SPMS; n=40), primary progressive MS (PPMS; n=24), clinically isolated syndrome (CIS; n=79), other neurological diseases (ONDs; n=181), ONDs with signs of inflammation or viral/bacterial infections (iONDs; n=176) and healthy controls (n=14).	21135023
Pulmonary Emphysema, Lung Injury	Altered Intercellular Communication	Our data demonstrate the critical role of membrane-localized CFTR in regulating ceramide accumulation and inflammatory signaling in lung injury and emphysema.	21135173
Inflammation, Temporal Arteritis	Altered Intercellular Communication	Biopsy of the prominent but nontender temporal arteries showed granulomatous inflammation, fragmentation, and duplication of the internal elastic lamina consistent with the temporal arteritis (TA).	21135707
Inflammation, Ulcer	Altered Intercellular Communication	To investigate whether thermography can be used to detect latent inflammation in pressure ulcers and predict pressure ulcer prognosis in a clinical setting.	21135794
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Low-grade systemic inflammation is emerging as a component of the metabolic syndrome.	21135979
Communicable Diseases, Inflammation, Hereditary hemochromatosis, hepcidin	Altered Intercellular Communication	Changes in the expression of hepcidin are known to be the key pathogenic factors in hereditary hemochromatosis and are associated with infection and inflammation.	21136275
Mesenteric Panniculitis	Altered Intercellular Communication	Panniculitis mesenteritis is a rare, benign, and chronic fibrosing inflammation disease with unknown aetiology that affects the mesentery of small bowel and colon.	21136368
Inflammation, Gallbladder Carcinoma	Altered Intercellular Communication	Preoperative inflammation is a prognostic factor for gallbladder carcinoma.	21136565
Inflammation, Gallbladder Carcinoma	Altered Intercellular Communication	Inflammation frequently accompanies gallbladder carcinoma (GBC), but its impact on outcome is unclear.	21136565
Inflammation, TNM Staging System, Neoplasms	Altered Intercellular Communication	In univariable analysis, preoperative inflammation, T, N and M category, TNM stage, radicality of surgery and tumour differentiation were significant prognostic factors.	21136565
Inflammation, Hepatobiliary Disorder, Diabetes Mellitus	Altered Intercellular Communication	pseudobaselloides Bailey is used as a Chinese folk medicine for treatment of diabetes, inflammation, and liver disease.	21138371
Fibrosis Assessment, Fatty degeneration, Necrosis with inflammation	Altered Intercellular Communication	At time of first biopsy, fibrosis stage was significantly higher in Asian patients than in Whites (3.0 +- 2.3 vs 1.8 +- 2.0, P < 0.001), as were necro-inflammation and steatosis scores.	21138506
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	[Systemic inflammation among stable ex smokers with chronic obstructive pulmonary disease].	21140052
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Low grade systemic inflammation is commonly observed in chronic obstructive pulmonary disease (COPD).	21140052
ARCN1 gene, Inflammation	Altered Intercellular Communication	To evaluate the extent of systemic inflammation in a group of ex-smokers with COPD in stable condition and its relation with pulmonary function and clinical manifestations.	21140052
Dyspnea, Inflammation	Altered Intercellular Communication	Patients with systemic inflammation had more AE in the previous year; lower inspiratory capacity, greater dyspnea during the six minutes walk test and worse SGRQ and CRQ scores.	21140052
ARCN1 gene, Inflammation	Altered Intercellular Communication	Low-grade systemic inflammation was found in 56 of 104 ex-smokers with COPD.	21140052
Celiac Disease, Crohn Disease, Inflammation	Altered Intercellular Communication	The detection of ASCA in patients with celiac disease allows to suggest that ASCA is not a specific marker for Crohn's disease, but was associated with the inflammation of the small intestine.	21140083
Inflammation, Atlanto-Axial joint, Atlantooccipital joint structure	Altered Intercellular Communication	A bony fusion of the atlanto-occipital joint after antibiotic treatment resolved the pyogenic inflammation concentrated stress to the damaged atlanto-axial joint, resulting in further damage.	21140176
Inflammation	Altered Intercellular Communication	It was proposed that asthma/chronic shortness of breath elicit chronic systemic inflammation even in the absence of episodic events.	21140796
Inflammation	Altered Intercellular Communication	Individuals with asthma/asthma-like symptoms have chronic low levels of systemic inflammation despite the absence of episodic pulmonary events.	21140796
Inflammation	Altered Intercellular Communication	Understanding chronic systemic inflammation relevant to asthma/asthma-like conditions may lead to design of targeted therapeutics.	21140796
Airway structure, ARCN1 gene	Altered Intercellular Communication	The TNF-a are involved in airway inflammation and the pathogenetic process of COPD, and may influence the lung function.	21140973
Exophthalmos, Neoplasms	Altered Intercellular Communication	Inflammations and tumors of the orbit and para-orbital regions may present as proptosis.	21141324
Inflammation, Corneal Stroma, Corneal Ulcer	Altered Intercellular Communication	Periphpral ulcerative keratitis (PUK) is a disorder consisting of a crescent-shaped destructive inflammation of the perilimbal corneal stroma.	21141332
Gingivitis, Pain Distress Question, Periodontitis, Gingiva	Altered Intercellular Communication	This case report describes a 2-year follow-up of a 30-year-old, female, chronic periodontitis patient, presenting severe gingival inflammation, sensitivity, pain, and acute gingival lesions that were treated with Er:YAG laser and conventional hand and ultrasonic instruments.	21142726
Inflammation, hepcidin	Altered Intercellular Communication	Use of a hepcidin-25 cut-off of <= 4 nmol/L allowed the differentiation of IDA from ACD and ACD/IRE, but not the discrimination of ACD from ACD/IRE in patients with severe inflammation.	21143009
Inflammation, Psoriasis	Altered Intercellular Communication	We previously demonstrated increased expression and activity of double-stranded RNA (dsRNA) receptors in psoriasis lesions, and suggested that this enhanced innate signalling contributed to the maintenance of psoriatic inflammation.	21143460
Inflammation	Altered Intercellular Communication	CT scans contributed only little to the final diagnosis, whereas increased CRP values and elevated erythrocyte sedimentation rates were more reliable indicators of inflammation in the sinuses.	21143525
Airway structure	Altered Intercellular Communication	The assessment of the presence of eosinophilic airway inflammation may help in predicting the steroid response in subjects with respiratory symptoms.	21143751
Airway structure, ARCN1 gene	Altered Intercellular Communication	Fractional exhaled nitric oxide (FENO) is a useful surrogate marker for eosinophilic airway inflammation, but data on the repeatability of FENO measurements in COPD needed for the assessment of significant change are insufficient.	21143751
Inflammation, Spondylitis	Altered Intercellular Communication	One of the most distinctive features of ankylosing spondylitis (AS) is new bone formation and bone resorption at sites of chronic inflammation.	21143847
Inflammation, Hyperplasia	Altered Intercellular Communication	Previous studies have indicated that the hyperplasia and inflammation of synovial tissues are significantly related to the pathogenic process of AS.	21143847
Inflammation, Atherosclerosis, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Low grade inflammation is of pathogenic importance in atherosclerosis and in the development of cardiovascular disease (CVD) and type 2 diabetes (T2D).	21143859
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The increased expression of these genes was predominantly observed in samples from UC patients and was associated with more intense inflammation.	21144017
Airway structure, Abnormality of the paranasal sinuses	Altered Intercellular Communication	to investigate the extent and characteristics of paranasal sinus abnormalities (anatomic and mucosal) on computed tomographic (CT) sinus scans and to determine whether there is a relationship between these findings and eosinophilic airway inflammation in patients with prednisone-dependent asthma.	21144367
Airway structure, Asthma	Altered Intercellular Communication	we conducted an observational survey of 15 prednisone-dependent asthmatic patients with respect to measures of airway inflammation and CT sinus scans.	21144367
Inflammation, C32 - zebrafish	Altered Intercellular Communication	Similarly, FPR1 C32T SNP is associated with inflammation and BP related pathways.	21144844
Cataract, Inflammation, Pain Distress Question	Altered Intercellular Communication	Twice-daily, preservative-free ketorolac 0.45% for treatment of inflammation and pain after cataract surgery.	21145532
Inflammatory abnormality of the eye	Altered Intercellular Communication	The primary efficacy end point was the percentage of patients with a summed ocular inflammation score of 0 for anterior chamber cell and flare on postoperative day 14.	21145532
Inflammatory abnormality of the eye	Altered Intercellular Communication	On day 14, 52.5% of ketorolac patients and 26.5% of vehicle patients had an summed ocular inflammation score of 0 (P < .001).	21145532
Cataract, Inflammation, Pain Distress Question	Altered Intercellular Communication	Twice-daily ketorolac 0.45% was well tolerated and effectively treated inflammation and pain following cataract surgery.	21145532
Wall of ventricle	Altered Intercellular Communication	B-type natriuretic peptide (BNP) is a neurohormone released from cardiomyocytes in response to volume expansion and increased ventricular wall distension.	21146031
Pulpitis	Altered Intercellular Communication	A first study on the usefulness of matrix metalloproteinase 9 from dentinal fluid to indicate pulp inflammation.	21146069
Intraocular inflammation	Altered Intercellular Communication	The primary safety measures were changes from baseline in VA, intraocular pressure (IOP), intraocular inflammation, and production of anti-KH902 antibody.	21146224
Intraocular inflammation, Retinal Hemorrhage, Low Vision, Toxic effect	Altered Intercellular Communication	Dose-limiting toxicity was defined as intraocular inflammation, elevated IOP, significantly reduced vision, or retinal hemorrhage within 42 days after injection.	21146224
Inflammation	Altered Intercellular Communication	Obesity-mediated inflammation may damage the brain circuit that regulates food intake.	21146506
Inflammation, Obesity	Altered Intercellular Communication	Adiposity is associated with chronic low-grade systemic inflammation and increased inflammation in the hypothalamus, a key structure in feeding behavior.	21146506
Stomatitis	Altered Intercellular Communication	Such restorations may facilitate the development of inflammations in the surface of the oral cavity, referred to as denture stomatitis.	21147619
Inflammation	Altered Intercellular Communication	Vascular endothelial growth factor (VEGF) is a multifunctional angiogenic cytokine that plays a significant role in inflammation and immune responses implicated in the pathogenesis of inflammatory processes in the implant- surrounding tissues.	21147629
Inflammation	Altered Intercellular Communication	The study confirmed that increased inflammatory cytokines lead to the persistence of inflammation in obese subjects.	21147638
Inflammation	Altered Intercellular Communication	TNF--a is one of the most important factors in the development and course of inflammation.	21147642
Inflammation, Fibrosis Assessment, Lung Diseases, Interstitial	Altered Intercellular Communication	Chronic inflammation and fibrosis are characteristic of interstitial lung diseases (ILD) and are accompanied by neovascularisation.	21147657
Autoimmune Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Because Th17 are potent inducers of tissue inflammation and autoimmunity, these results suggest impact on the clinical management of various types of malignancies treated with alkylating agents and a potential need to optimize CTX-based immunotherapy in patients.	21148486
Inflammation	Altered Intercellular Communication	Childhood adversity heightens the impact of later-life caregiving stress on telomere length and inflammation.	21148804
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	To examine prospectively the association of psychological distress with the development of the metabolic syndrome (MetS) and the potential influence of demographic characteristics, health behaviors, and inflammation in this association.	21148808
Hyperlipidemia, vascular inflammations	Altered Intercellular Communication	Vascular inflammation measured using 18F-FDG PET was increased in healthy individuals without hyperlipidemia but with elevated hsCRP.	21149476
Inflammation, varicella zoster, Necrotizing, Herpes Simplex Infections, Mapuche Language	Altered Intercellular Communication	Herpes simplex and varicella zoster viruses can cause a wide spectrum of clinical manifestations ranging from severe ARN to slow-progressing necrotizing and non-necrotizing types of inflammation.	21149747
Cataract, Intraocular inflammation, Retinal Detachment	Altered Intercellular Communication	He developed severe intraocular inflammation and required a pars plana lensectomy, vitrectomy, and scleral buckle after developing a cataract and retinal detachment.	21149777
Retinal Degeneration, Communicable Diseases, Inflammation	Altered Intercellular Communication	Infection or inflammation within the retina early in life may lead to an autoimmune phenocopy of early-onset inherited retinal degeneration.	21149784
Dermatitis, Atopic, Inflammation, Data types - Address	Altered Intercellular Communication	Topical pimecrolimus may maintain remissions of atopic dermatitis (AD) by inhibiting subclinical inflammation.	21150167
Inflammation	Altered Intercellular Communication	This article proposes that inflammation leading to intestinal permeability (a leaky gut) may be responsible for numerous physical and mental abnormalities and associated functional decline.	21150504
Renal Insufficiency, Electrocardiogram: left ventricle hypertrophy (finding), Chronic Kidney Diseases	Altered Intercellular Communication	The hemodynamic alterations induced by the impairment of renal function explain only in part the development of left ventricular hypertrophy in patients with chronic kidney disease (CKD), who are theoretically exposed to an inappropriate high growth of left ventricular mass (iLVM) due to the activation of neuro-hormonal stressors.	21150636
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	NT-proBNP and circulating inflammation markers in prediction of a normal myocardial scintigraphy in patients with symptoms of coronary artery disease.	21152016
Tears body substance, Inflammation	Altered Intercellular Communication	Too close distance of the implant towards dural sac, particularly in case of dural tears, fistulae or overt inflammation.	21153009
Retinal Neoplasms, Retinitis, Neoplasms	Altered Intercellular Communication	Vasoproliferative retinal tumors are benign tumors of unknown origin often accompanied by vitreoretinal inflammation.	21153829
Inflammation, Malignant neoplasm of endometrium	Altered Intercellular Communication	Chronic inflammation has been hypothesized to play a role in endometrial cancer development.	21154749
Inflammation, Ototoxicity	Altered Intercellular Communication	Some of the associated pathogenic changes are amyloid peptide aggregation, excitotoxicity, oxidative stress and inflammation.	21154880
Airway structure	Altered Intercellular Communication	Fractional exhaled nitric oxide (FENO) is a marker of airway inflammation.	21155706
melanoma, Inflammation, Neoplasms	Altered Intercellular Communication	Melanoma is often infiltrated by inflammatory and immune cells that might either maintain chronic inflammation, therefore promoting tumour growth, or mount an antitumour response to control tumour outcome.	21155750
Inflammation, Psoriasis, Dermatitis, Atopic, Dermatologic disorders, Data types - Address	Altered Intercellular Communication	Skin diseases such as psoriasis, characterized by keratinocyte hyperproliferation, and atopic dermatitis (AD), dominated by cutaneous inflammation, might have an impact on viral life cycle and immune response induction.	21155755
Inflammation	Altered Intercellular Communication	Aberrant expression of epidermal growth factor receptor and its interaction with protein kinase C d in inflammation associated neoplastic transformation of human esophageal epithelium in high risk populations.	21155880
Inflammation, Alcoholic Intoxication, Chronic	Altered Intercellular Communication	Altogether, our findings reveal that the activation of EGFR and its subsequent interaction with PKCd under inflammatory conditions might positively be attributed to the transformation of normal esophageal epithelia to SCC, which could explain ongoing inflammation in normal mucosa in a population prone to smoking and alcoholism.	21155880
Inflammation, Alcoholic Intoxication, Chronic	Altered Intercellular Communication	Altogether, our findings reveal that the activation of EGFR and its subsequent interaction with PKCd under inflammatory conditions might positively be attributed to the transformation of normal esophageal epithelia to SCC, which could explain ongoing inflammation in normal mucosa in a population prone to smoking and alcoholism.	21155880
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	In a total of 190 areas observed with magnifying NBI, histological grading (inflammation, activity, atrophy and intestinal metaplasia) showed significant differences among the classified micromucosal patterns (P < 0.001).	21155881
Inflammatory Bowel Diseases, Crohn Disease, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) and Crohn's disease (CD) are two major phenotypes of inflammatory bowel disease (IBD) that present with inflammation of the colon or the entire gastrointestinal tract, respectively.	21155887
allergic inflammation, Data types - Address	Altered Intercellular Communication	Specific IgE reactivities against a variety of bacterial antigens were observed in a subgroup comprising a third of AD patients and may contribute to allergic inflammation.	21155910
Communicable Diseases, Inflammation, Edema	Altered Intercellular Communication	The clinical presentation was in the form of an epithelial defect, suspected epithelial down growth, graft oedema with unexplained anterior chamber inflammation and graft-host interface infection.	21155984
Heart Diseases, Giant Cell Arteritis, vascular inflammations	Altered Intercellular Communication	Bilateral CRAO is a rare disease usually found in patients with cardiac embolic diseases, giant cell arteritis or systemic vascular inflammations.	21157081
Amyotrophic Lateral Sclerosis, Inflammation, Congenital Abnormality, Small Fiber Neuropathy	Altered Intercellular Communication	nine patients had increased uptake of F-18 FDG, indicating inflammation, in 25 areas of soft tissue and/or bone without concurrent bony abnormalities on CT. presented F-18 FDG PET/CT data may indicate an inflammatory origin of Charcot disease, with secondary bone resorption, possibly due to decreased inhibitory neurogenic inflammatory responses as a result of small fiber neuropathy.	21157199
Inflammation	Altered Intercellular Communication	There are reported cases of uptake on Octreoscans at other sites of the body due to chronic inflammation, but only one other case has been reported in the brain.	21157209
Inflammation, Lens Opacities	Altered Intercellular Communication	The main outcome measures included retinal reattachment, visual acuity, intraocular pressure, intraocular inflammation, lens opacity, and HSO emulsification.	21157397
Airway structure, Respiratory Hypersensitivity	Altered Intercellular Communication	Testing for airway hyperresponsiveness with indirect stimuli as exercise or mannitol has been proposed to better reflect underlying airway inflammation, as compared with methacholine (MCh), believed to act directly on airway smooth muscle cells.	21159136
Inflammation	Altered Intercellular Communication	There is growing evidence that inflammation plays an important role in atherogenesis.	21159472
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Upregulation of surrogate markers of inflammation and thrombogenesis in patients with ESRD: pathophysiologic and therapeutic implications.	21159713
Inflammation, Carcinogenesis	Altered Intercellular Communication	Chemopreventive dietary compounds, such as flavonols, may inhibit colorectal carcinogenesis partly by altering cytokine expression and attenuating inflammation.	21160427
Arthritis, Erosion of bone	Altered Intercellular Communication	This may represent an autocrine mechanism to limit the degree of bone erosion during joint inflammation.	21162099
Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	The level of TSG-6 protein was determined in SF from patients with various arthritides; it was highest in patients with inflammatory conditions such as rheumatoid arthritis, in which it correlated with the amount of TSG-6 immunostaining in the synovium.	21162099
Keratitis	Altered Intercellular Communication	Corneal inflammation was successfully managed with topical steroids, oral methylprednisolone, and methotrexate.	21162464
hearing impairment, Inflammation	Altered Intercellular Communication	A 16-year-old male with recurrent inflammation and hearing loss.	21162483
Granulomatous inflammation	Altered Intercellular Communication	Biopsy specimens demonstrated granulomatous inflammation and acid-fast bacilli with the use of a Fite stain, although a culture and polymerase chain reaction analysis were negative.	21163172
Chronic Kidney Diseases	Altered Intercellular Communication	Advanced Chronic Renal Disease (CKD) is closely associated with a pro-inflammatory condition, with an increase in triglyceride-rich lipoproteins and decrease in HDL level.	21163737
AURKAIP1 gene, Inflammation, Pancreatitis	Altered Intercellular Communication	In comparison with the cohort of chronic pancreatitis, not otherwise specified, type 2 AIP cases were less likely to be associated with a history of alcohol abuse, and showed significantly more foci of periductal inflammation and neutrophilic microabscesses.	21164284
Inflammation, Scleritis, Nodular scleritis	Altered Intercellular Communication	Nodular scleritis was the most common form observed, followed by necrotizing scleritis with inflammation, diffuse scleritis, and necrotizing scleritis without inflammation, respectively.	21165230
Inflammation, Hyperparathyroidism, Primary, Endothelial dysfunction	Altered Intercellular Communication	Increased markers of inflammation and endothelial dysfunction in patients with mild primary hyperparathyroidism.	21166606
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Patients with mild PHPT and normal renal function displayed signs of subclinical inflammation and endothelial dysfunction.	21166606
ARCN1 gene, Airway structure	Altered Intercellular Communication	3-Chlorotyrosine in sputum of COPD patients: relationship with airway inflammation.	21166629
ARCN1 gene, Inflammation, Inflammatory disorder	Altered Intercellular Communication	Contained within the primary granules of neutrophils is the heme enzyme called myeloperoxidase (MPO) that has been used as a biomarker of neutrophilic inflammation in COPD and other inflammatory diseases.	21166629
Inflammation, Obesity, Abdominal, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	These findings showed that insulin resistance was associated with CRP levels independent of abdominal obesity in Chinese patients with type 2 diabetes, suggesting that abdominal obesity could only partly explain the link between subclinical inflammation and insulin resistance.	21167068
Inflammation, Ischemic stroke	Altered Intercellular Communication	Enteral formula containing whey protein may decrease inflammation and increase antioxidant defenses in elderly patients with ischemic stroke, compared to casein-containing formula.	21167685
Granuloma, Fibrosis Assessment, Ear Inflammation	Altered Intercellular Communication	Morphology in chronic HP is characterized by bronchiolocentric mononuclear inflammation, poorly formed granulomas and variable degree of fibrosis.	21167698
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Liver biopsy samples were analyzed (for fibrosis, inflammation, and steatosis) before patients received standard antiviral therapy.	21167831
Fibrosis Assessment, Fatty degeneration, Hepatitis	Altered Intercellular Communication	Baseline levels of liver inflammation, fibrosis, steatosis, serum interleukin-6 (P = .04), and hepatic TNF-a (P = .007) were significantly higher among postmenopausal women than women of reproductive age.	21167831
Inflammation, Impaired cognition, millicurie, Data types - Address, amyloid-beta binding	Altered Intercellular Communication	To better investigate inflammation in AD we performed an extensive immunophenotypic and functional analysis of amyloid-beta (Ab) stimulated T lymphocytes in patients with a diagnosis of AD comparing data to those obtained in individuals with mild cognitive impairment (MCI) or aged-matched healthy individuals (HC).	21167930
Tauopathies, Depression, CTCAE	Altered Intercellular Communication	Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission.	21167950
Granulomatous inflammation, Caseous necrosis	Altered Intercellular Communication	Histopathological examination of the biopsy specimen showed granulomatous inflammation and caseous necrosis.	21168119
Inflammation, Hypoxia, Anemia, hepcidin	Altered Intercellular Communication	The production by hepatocytes of hepcidin, a small defensin-like peptide, is modulated in response to anemia, hypoxia, or inflammation.	21168677
Inflammation, Renal function, hepcidin, Kidney Transplantation	Altered Intercellular Communication	In conclusion, elevated hepcidin levels in heart and kidney transplant recipients suggest subclinical inflammation and impaired kidney function.	21168677
Inflammation	Altered Intercellular Communication	Glycodelin (Gd), which is localized in cells of bronchial epithelium, type II pneumocytes and alveolar macrophages in rats and humans, plays an important role in the pulmonary immune response in asthmatic inflammation.	21168900
Cessation of life, Inflammation	Altered Intercellular Communication	The inflammatory process is related to oxidative stress and inflammation was proven to be a strong determinant of the aging process and to ultimately lead to death.	21169033
Inflammation	Altered Intercellular Communication	GSTM1 wildtype is associated with reduced mortality among older adults with high levels of inflammation, but not among those with low levels of inflammation.	21169033
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Elevated proinflammatory cytokine production by a skewed T cell compartment requires monocytes and promotes inflammation in type 2 diabetes.	21169542
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Recent work indicates T cells are important mediators of inflammation in a mouse model of T2D.	21169542
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	These data indicate that T cells in T2D patients are naturally skewed toward proinflammatory subsets that likely promote chronic inflammation in T2D through elevated cytokine production.	21169542
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	The simultaneous measurement of Th1-related chemokines (CXCL10 and MIP-1a) and of Th2-related chemokine MIP-1b in the serum of patients with AAD would sustain a novel preliminary hypothesis on the immune microenvironment of chronic autoimmune inflammation within adrenal glands.	21169727
Inflammation, Traumatic	Altered Intercellular Communication	This study demonstrates the feasibility of microdialysis in recovering cytokines for a prolonged time, although there may be some nonresolved methodologic problems with this technique when we try to study the inflammation during traumatic brain injury that could affect the results and make interpretation of microdialysis data prone to difficulties.	21169825
Inflammation, Atherosclerosis	Altered Intercellular Communication	Adipokines such as adiponectin and resistin, as well as angiogenin, may be associated with inflammation and atherosclerosis.	21169907
Inflammation, Mixed Connective Tissue Disease	Altered Intercellular Communication	A 45-year old women with MCTD developed multiple LLU's with non-specific inflammation by biopsy.	21169912
Sialadenitis	Altered Intercellular Communication	Inflammation was the predominant pathological finding (49.5%), of which non-specific chronic sialadenitis constituted the majority (86.9%).	21170719
Inflammation	Altered Intercellular Communication	Prominent histological findings of chronic inflammation were not evident in either alcoholics or non-alcoholics.	21171086
Inflammation, Observation Method - Coagulation, Endothelial dysfunction	Altered Intercellular Communication	Other markers of inflammation, coagulation, and endothelial dysfunction increased comparably in both groups during CPB.	21172477
Inflammation	Altered Intercellular Communication	Alterations in retinal vascular calibre, particularly wider venular calibre, have been independently associated with elevated markers of inflammation and cardiovascular risk in the general population.	21172929
Refractory anemias, Inflammation	Altered Intercellular Communication	We hypothesized that retinal vascular calibre would be altered in patients with RA, who are known to have both elevated cardiovascular risk and chronic, systemic inflammation.	21172929
Refractory anemias, Inflammation	Altered Intercellular Communication	The relationship between retinal venular calibre and inflammation was assessed by comparing controls and RA patients with high and lower disease activity.	21172929
Refractory anemias, Inflammation	Altered Intercellular Communication	also increased with increasing levels of systemic inflammation: 211.6 (21.0) um in controls, 232.3 (22.4) um in RA patients with moderate or lower disease activity and 255.5 (28.3) um in RA patients with high disease activity (P for trend < 0.0001).	21172929
Refractory anemias, Inflammation	Altered Intercellular Communication	This study demonstrates that RA patients have dilated retinal venular calibre, reflecting systemic inflammation and possibly increased cardiovascular risk.	21172929
Inflammation	Altered Intercellular Communication	LN was associated with the degree of synovial inflammation.	21173012
Inflammation, Thrombosis, Thrombocytosis, Polycythemia Vera	Altered Intercellular Communication	Inflammation and thrombosis in essential thrombocythemia and polycythemia vera: different role of C-reactive protein and pentraxin 3.	21173097
Inflammation, Pancreatic carcinoma	Altered Intercellular Communication	Our results highlight the importance of investigating more specific biomarkers for inflammation that may reflect the biological mechanisms underlying pancreatic cancer in prospective cohort studies.	21173171
Inflammation, Cardiac dysfunction, Cardiovascular Diseases	Altered Intercellular Communication	Plasma BNP levels increased with respect to the severity of cardiac dysfunction and serum CRP levels, and should therefore be considered a collective or total marker for life-threatening conditions including systemic inflammation, and not simply as a marker of cardiac dysfunction in patients with cardiovascular diseases.	21173540
Inflammation, Sarcoidosis	Altered Intercellular Communication	Sarcoidosis is a systemic granulomatous inflammation of unknown etiology, and seems to involve the liver parenchyma in most cases.	21173811
Granulomatous inflammation, Liver carcinoma, Neoplasms	Altered Intercellular Communication	Histology revealed a hepatocellular carcinoma accompanied by T-lymphocytic infiltration and marked granulomatous inflammation, which was surrounding some tumor nodules.	21173811
Granulomatous inflammation, Fibrosis Assessment	Altered Intercellular Communication	The background liver parenchyma exhibited a moderate degree of fibrosis with granulomatous inflammation.	21173811
Fever, CTCAE, Chemosis of conjunctiva, Illness (finding), Orbital Cellulitis, Exophthalmos	Altered Intercellular Communication	Orbital cellulitis is an acute inflammation of the orbital content with exophthalmos, chemosis, blepharedema, reduction of eyeball motility and generalized illness, occasionally with fever.	21174101
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The pleiotropic cytokine oncostatin M (OSM), a member of the glycoprotein (gp)130 ligand family, plays a key role in inflammation and cardiovascular disease.	21174212
Inflammation, Atherosclerosis	Altered Intercellular Communication	Adiponectin and resistin, as well as the novel angiogenetic factor angiogenin, may be associated with inflammation and atherosclerosis.	21174281
Inflammatory Bowel Diseases, Crohn Disease	Altered Intercellular Communication	Crohn's disease is a chronic inflammatory bowel disease characterized by transmural, granulomatous inflammation.	21175234
Inflammation, Endotoxemia	Altered Intercellular Communication	Low-grade endotoxemia contributes to chronic inflammation in hemodialysis patients: examination with a novel lipopolysaccharide detection method.	21175546
Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Chronic inflammation has recently been proposed to play a major role in the development of cardiovascular disease and mortality among advanced chronic kidney disease (CKD) patients; however, why advanced CKD promotes chronic inflammation is still unclear.	21175546
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We hypothesized that a very low level of plasma endotoxin (lipopolysaccharide [LPS]) contributes to chronic inflammation in advanced CKD patients.	21175546
HD Term Type, Inflammation, Endotoxemia	Altered Intercellular Communication	In conclusion, the present study revealed a significant relationship between LPS and CRP using the novel ESP method, and suggested that very low-grade endotoxemia is contributing to systemic inflammation in HD patients.	21175546
Myeloma cell, Inappropriate ADH Syndrome	Altered Intercellular Communication	Syndrome of inappropriate antidiuretic hormone secretion associated with plasma cell myeloma.	21175565
square decimeter, Metabolic Syndrome X, Diabetes Mellitus	Altered Intercellular Communication	Insulin-resistant states, such as metabolic syndrome and diabetes mellitus type 2 (DM2), have been associated with chronic low-grade systemic inflammation.	21175613
ARCN1 gene, Inflammation, Chronic disease of respiratory system	Altered Intercellular Communication	1) The scavenging and anti-inflammatory effects of Erdosteine were both confirmed; 2) erdosteine proved to affect eicosanoids significantly; 3) this novel effect underlines the important anti-inflammatory potentialities of the drug in COPD; 4) further investigation is needed in order to assess the capability of Erdosteine in controlling ongoing inflammation in chronic respiratory diseases.	21176724
Inflammation, Tumor necrosis	Altered Intercellular Communication	Inflammation plays an important role in insulin resistance, and adipocytokines, including tumor necrosis factor-alpha and leptin, can induce insulin resistance.	21176750
Inflammation, Periodontitis, Malnutrition	Altered Intercellular Communication	Our previous work suggests that periodontitis is associated with malnutrition and inflammation.	21177012
Inflammation	Altered Intercellular Communication	There was no significant difference between the groups in disease activity, measures of inflammation or endothelial cell activation.	21177297
ARCN1 gene, Inflammation, Cardiovascular Diseases, Diabetes Mellitus, Obesity	Altered Intercellular Communication	Three COPD groups were identified: group 1 (n=126, 67 years) was characterised by severe airflow limitation (postbronchodilator forced expiratory volume in 1 s (FEV(1)) 38% predicted) and worse performance in most of the respiratory domains of the disease; group 2 (n=125, 69 years) showed milder airflow limitation (FEV(1) 63% predicted); and group 3 (n=91, 67 years) combined a similarly milder airflow limitation (FEV(1) 58% predicted) with a high proportion of obesity, cardiovascular disorders, diabetes and systemic inflammation.	21177668
Inflammation	Altered Intercellular Communication	Our results indicate that novel anti-inflammatory drugs may resolve imbalanced inflammation and improve outcomes in older people infected with viruses.	21178458
Inflammation, Cachexia	Altered Intercellular Communication	Protein-energy wasting modifies the association of ghrelin with inflammation, leptin, and mortality in hemodialysis patients.	21178976
Inflammation, Congenital Abnormality, Anorexia	Altered Intercellular Communication	Ghrelin abnormalities contribute to anorexia, inflammation, and cardiovascular risk in hemodialysis patients, leading to worse outcome.	21178976
Inflammation, Hypertension, CTCAE, Endothelial dysfunction, Cardiovascular Diseases	Altered Intercellular Communication	Chronic inflammation and endothelial dysfunction may be associated with hypertension and cardiovascular disease.	21179100
Inflammation, Hypertension, CTCAE, Endothelial dysfunction	Altered Intercellular Communication	This study suggests that inflammation and endothelial dysfunction may have a role in the development of hypertension.	21179100
Inflammation, Pneumonia, Interstitial, Interstitial Fibrosis Assessment, Nonspecific interstitial pneumonia	Altered Intercellular Communication	An open lung biopsy of the right middle lobe under general anesthesia revealed chronic peribronchial inflammation, mild interstitial fibrosis, and intra-alveolar macrophage infiltration, with some hemosiderin features, compatible with non-specific interstitial pneumonia (NSIP).	21179284
Inflammation	Altered Intercellular Communication	IL-6 may serve as warning sign, because it increases early in inflammation.	21179922
Inflammation, Dysplasia, Infection caused by Helicobacter pylori, Metaplasia, Liver regeneration disorder, Atrophic	Altered Intercellular Communication	We evaluated several histopathological parameters, correlating the degree of inflammation, atrophy, metaplasia, regenerative hyperplasia and dysplasia with the presence of H. pylori infection.	21180246
Communicable Diseases, Inflammation	Altered Intercellular Communication	Tenascin-C (TN-C) is an adhesion-modulating extracellular matrix glycoprotein which is overexpressed in various organs under disease conditions (infection and inflammation).	21183183
Inflammation, Chronic Kidney Diseases, Cardiovascular morbidity	Altered Intercellular Communication	Chronic kidney disease (CKD) is associated with a state of chronic inflammation and high cardiovascular morbidity and mortality.	21183183
Airway structure, MS4A2 wt Allele	Altered Intercellular Communication	However, it is uncertain if fraction of exhaled nitric oxide (Feno), which is used as a marker of airway inflammation, and atopy are associated with BMI.	21183611
Inflammation	Altered Intercellular Communication	Relation of C. pneumoniae antibodies to inflammation and atherosclerosclerosis in dialysis patients.	21183888
methyldopa, Inflammation, Inflammatory disorder, Uveitis	Altered Intercellular Communication	Although age-related macular degeneration (AMD) is not a classic inflammatory disease like uveitis, inflammation has been found to have an important role in disease pathogenesis and progression.	21183941
Inflammation, Hypertensive (finding), Endothelial dysfunction, diabetic	Altered Intercellular Communication	Endothelial dysfunction, a common feature among hypertensive and type-2 diabetic patients, has been associated with inflammation and increased concentrations of serum soluble adhesion molecules and resistin, a monocyte-macrophage- and adipocyte-derived cytokine.	21184654
Esophageal Stricture, Eosinophilic esophagitis, "Extra-osseous Ewings sarcoma	Altered Intercellular Communication	Eosinophilic esophagitis (EoE) is a chronic inflammatory condition that can be complicated by esophageal strictures requiring endoscopic dilation.	21184880
Tip Breakage, Failure (biologic function)	Altered Intercellular Communication	Failure occurred because of breakage (14) or exuberant inflammation (31).	21185695
Inflammation, Diabetic Retinopathy, GDC Disease Response Terminology	Altered Intercellular Communication	Inflammation has been linked to the development of diabetic retinopathy (DR).	21185877
Inflammation, Wrist joint	Altered Intercellular Communication	Epidemiology of suspected wrist joint infection versus inflammation.	21186086
Communicable Diseases, Inflammation, Arthritis, Infectious	Altered Intercellular Communication	To determine the cumulative prevalence of septic arthritis presenting to the emergency department of an academic medical center and evaluate the use of clinical data to diagnose infection versus inflammation.	21186086
Atherosclerosis	Altered Intercellular Communication	Resistin is a pro-inflammatory signaling molecule that is thought to contribute to atherosclerosis.	21187261
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Intracellular heavy metal nanoparticle storage: progressive accumulation within lymph nodes with transformation from chronic inflammation to malignancy.	21187947
Inflammation, S100A4 protein, human	Altered Intercellular Communication	Heavy metals from environmental pollution may accumulate in sites far from the entry route and, in genetically conditioned individuals with tissue specificity, may act as cofactors for chronic inflammation or even malignant transformation.	21187947
Inflammation	Altered Intercellular Communication	We performed a retrospective analysis in 163 SCT recipients of which data had been collected prospectively on intestinal damage (citrulline), inflammation (C-reactive protein), and neutrophil count.	21188146
Inflammatory Bowel Diseases, Inflammation, Hemorrhage, pancolitis, Ulcer, Ulceration, CTCAE	Altered Intercellular Communication	Colonoscopy showed pancolitis with numerous ulcers; the biopsy showed foci of inflammation, ulceration and hemorrhage in the lamina propria, without features of chronic inflammatory bowel disease.	21188339
Inflammation, Pain Distress Question	Altered Intercellular Communication	Thus, inflammation may play an important role in bidirectional associations between pain and sleep.	21188850
Inflammation, Chronic pain	Altered Intercellular Communication	Little is known about concurrent relationships among chronic pain, sleep, and inflammation.	21188850
Communicable Diseases, Inflammation	Altered Intercellular Communication	CRP levels, plasma glucose levels, lipid profiles, and blood tests were performed to investigate any conditions that might have suggested infection and/or inflammation.	21189085
Symptoms, Inflammation	Altered Intercellular Communication	Asthma symptoms, lung function, and markers of oxidative stress and inflammation in children exposed to oil refinery pollution.	21189114
Inflammation, Asthma, Wheezing	Altered Intercellular Communication	We evaluated lung function and markers of inflammation and oxidative stress in children and adolescents with and without asthma or wheezing symptoms living in a petrochemical polluted area (Sarroch, Sardinia) versus a reference area (Burcei).	21189114
Sneezing, Bronchitis	Altered Intercellular Communication	Children living in Sarroch versus children living in the reference area showed an increase in wheezing symptoms {adjusted prevalence ratio=1.70 [90% confidence interval (CI)=1.01; 2.86]}; a decrease in lung function [variation in FEV(1)=-10.3% (90% CI=-15.0; -6.0%) and in FEF(25-75)=-12.9% (90% CI=-20.7; -4.3%)]; an increase in bronchial inflammation [variation in FE(NO)=+35% (90% CI=11.7; 80.1%)]; and an increase in MDA-dG adducts of +83% (90% CI=22.9; 174.1%).	21189114
Inflammation	Altered Intercellular Communication	Data from this small study are consistent with the role of environmental pollutants on lung function and inflammation.	21189114
Inflammation, Decompensated chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Small intestinal function may be altered in decompensated chronic heart failure (CHF) and translocating LPS may contribute to systemic inflammation observed in CHF.	21190739
Inflammation, Congestive heart failure	Altered Intercellular Communication	Higher LPS concentrations in edematous CHF relate to inflammation.	21190739
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is associated with the development of atherosclerotic vascular lesions and some inflammatory parameters are used as cardiovascular (CV) risk markers.	21190868
Inflammation, Atherosclerosis, Chronic inflammatory disorder	Altered Intercellular Communication	Therefore, accumulation of senescent monocytes may explain, in part, the development of chronic inflammation and atherosclerosis in elderly subjects and in patients with chronic inflammatory diseases.	21191073
Inflammation, Septic Shock	Altered Intercellular Communication	Midkine significantly increased along with a sequence: health-inflammation (IBD)-systemic inflammation (IBD-SIRS)-severe sepsis/septic shock.	21192283
Sepsis, Inflammation, Septic Shock	Altered Intercellular Communication	In conclusion, sepsis and septic shock are associated with midkine elevation, substantially more pronounced than in inflammation, even systemic, revealing a new potential mediator of deregulation of neutrophil migration.	21192283
Inflammation, Granulation procedure	Altered Intercellular Communication	Several recent studies suggest a high-intensity zone (HIZ) within the posterior annulu of lumbar intervertebral disc seen on T2-weighted magnetic resonance (MR) images represents the inflammation in the annulus, an annular tear, and/or vascular granulation tissue.	21192298
Inflammation, Granulation procedure	Altered Intercellular Communication	There have been studies suggesting that the presence of HIZ reflects inflammation in the annulus, an annular tear, and/or vascular granulation tissue.	21192298
Schizophrenia, Autistic Disorder, Infection	Altered Intercellular Communication	Infections and inflammatory conditions during pregnancy can dysregulate neural development and increase the risk for developing autism and schizophrenia.	21192986
Inflammation, Ischemic stroke, Cardiovascular Diseases	Altered Intercellular Communication	Seventy-seven single nucleotide polymorphisms (SNPs) of 53 candidate genes for cardiovascular disease and inflammation were genotyped in 1327 patients with no past history of ischemic stroke.	21193198
Weight decreased, Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Effect of weight loss on inflammation in patients with mild obstructive sleep apnea.	21193295
Inflammation, Sleep Apnea, Obstructive, Cardiovascular Diseases, Osage language	Altered Intercellular Communication	Inflammation may be one mediating mechanism for cardiovascular diseases in obstructive sleep apnea (OSA).	21193295
Inflammation, Osage language	Altered Intercellular Communication	However, little is known about subclinical inflammation or the effect of lifestyle intervention on inflammation in early stages of OSA.	21193295
HD Term Type, Chronic Kidney Diseases, Malnutrition, Inflammation	Altered Intercellular Communication	Main exclusion criteria for patients with CKD and HD were severe protein-caloric malnutrition and inflammation (measured by high sensitivity C-reactive protein and interleukin-6 levels).	21193322
Inflammation, Chronic Kidney Diseases, Anorexia	Altered Intercellular Communication	Inflammation and loss of appetite is the most common problem in patients with chronic kidney disease (CKD).	21193324
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The degree of inflammation (0-18) and fibrosis (0-6) according to Ishak score was compared between the initial and the follow-up biopsy.	21194803
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation, an important mechanism in the pathogenesis of atrial fibrillation (AF), can be regulated by CD36 in monocytes.	21195211
Inflammation	Altered Intercellular Communication	Annexin A1, a calcium and phospholipid-binding protein, is an important endogenous modulator of inflammation.	21195640
Inflammation, Chronic Kidney Diseases, Kidney Diseases, Ischemia	Altered Intercellular Communication	Possible sources are an inadequate persistent inflammation and ischemia as a consequence of CKD or caused by the underlying renal disease.	21195700
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The mechanisms to affect inflammation and clinical outcome in rheumatoid arthritis are only partly understood.	21196744
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Metabolic phenotype and adipose tissue inflammation in patients with chronic obstructive pulmonary disease.	21197447
ARCN1 gene, Inflammation, Metabolic Diseases, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Potential links between metabolic derangements and adipose tissue (AT) inflammation in patients with chronic obstructive pulmonary disease (COPD) are unexplored.	21197447
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Our results suggest that AT inflammation in obese COPD patients relates to insulin resistance.	21197447
glycation, vascular inflammations, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The levels of soluble receptor for advanced glycation end products (sRAGE) may reflect the activity of the advanced glycation end products-RAGE axis, which has been proposed as a potential mechanism of vascular inflammation in patients with type 2 diabetes (T2D).	21197704
Inflammation, Electrocardiogram: myocardial infarction (finding), Atherosclerosis	Altered Intercellular Communication	Inflammation and genetics play a key role in the pathogenesis of atherosclerosis and its clinical result myocardial infarction (MI).	21199393
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	It has been recently shown that inflammation may play a role in myocardial ischemia.	21199731
methyldopa, Inflammation	Altered Intercellular Communication	The results of the current study show that the as-yet undetermined function of variants in the ARMS2/HTRA1 locus might be linked to inflammation, possibly contributing to the development of neovascular AMD.	21203342
Inflammation, Chronic disease	Altered Intercellular Communication	The plasma proteins are implicated in chronic diseases, inflammation, endothelial function and metabolic signaling.	21203453
Inflammation, Pancreatitis, Necrosis	Altered Intercellular Communication	contrast enhanced ultrasound provides information on the vascularization of the pancreatic parenchyma, detecting areas of inflammation, necrosis, as well as the residual parenchyma in acute pancreatitis.	21203596
Inflammation, Necrosis	Altered Intercellular Communication	The analysis of the average value of the maximum acoustic signal intensity (max I) after contrast injection, and of the mean time to signal enhancement appearance (mT): a) superior mesenteric artery: max I 19.37 +/- 8.53 dB, mT 15.85 +/- 4.6 sec; b) inflammation area: max I 14.76 +/- 6.7 dB, mT 15.15 +/- 3.6 sec; c) necrosis area: max I 8.89 +/- 9.91 dB, mT 22.17 +/- 7.9 sec; d) structural ill-defined hypoechoic area: max I 12.03 +/- 5.4 dB, mT 21.67 +/- 4.47 sec.	21203596
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Aging linked to type 2 diabetes increases oxidative stress and chronic inflammation.	21204649
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Oxidative stress (OxS) and inflammation are physiopathological mechanisms related to diabetes and aging.	21204649
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Our findings suggest that aging, in concert with diabetes, exerts an additive effect on OxS and inflammation.	21204649
Inflammation, Meningitis	Altered Intercellular Communication	Meningitis is an inflammation of the protective membranes covering the brain and spinal cord caused by bacteria, fungi, or viruses with various clinical symptoms.	21204701
Refractory anemias, Inflammation, Damage, Rheumatoid Arthritis	Altered Intercellular Communication	IL-17-producing T cells (Th17 cells) are believed to contribute to local inflammation and joint damage in rheumatoid arthritis (RA).	21204897
Inflammation, Squamous cell carcinoma, SERPINB3 wt Allele	Altered Intercellular Communication	In the oral cavity, chronic inflammation has been observed at various stages of oral squamous cell carcinomas (OSCC).	21205002
Inflammation	Altered Intercellular Communication	Such inflammation could result from persistent mucosal or epithelial cell colonization by microorganisms.	21205002
Inflammation, SERPINB3 wt Allele	Altered Intercellular Communication	There is increasing evidence of the involvement of oral bacteria in inflammation, warranting further studies on the association of bacteria with the progression of OSCC.	21205002
Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Diabetes Mellitus	Altered Intercellular Communication	To examine whether interleukin-1 receptor antagonist (IL-1Ra) is a predictor for clinically incident diabetes in subjects with metabolic syndrome (MetS) and whether its predictive power is independent of C-reactive protein (CRP), an established marker of inflammation.	21205020
Hepatic inflammation, FAM126A gene	Altered Intercellular Communication	In early-stage HCC, B-HCC patients had better outcomes than C-HCC patients did because of better liver reserve and less hepatic inflammation.	21207029
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Prospective studies have reported associations among various markers of inflammation and the incidence of diabetes, and it has been proposed that inflammation has a causal role in the development of diabetes.	21207147
vascular inflammations	Altered Intercellular Communication	A growing body of evidence has suggested that RAGE may promote vascular inflammation through several mechanisms.	21208063
Inflammation	Altered Intercellular Communication	Regulation of IL-17 in chronic inflammation in the human lung.	21208193
Inflammation, Chronic inflammatory disorder	Altered Intercellular Communication	Currently, as there is interest in the role of IL-17-producing cells and Treg cells in chronic inflammatory diseases in humans, we investigated the presence of CD4(+)CD25(+) T-cells and IL-17 in inflammation in the human lung.	21208193
Pneumonitis	Altered Intercellular Communication	Transcripts for IL-17 were expressed in mononuclear cells and purified T-cells from lung tissue of patients with chronic pulmonary inflammation and, when activated, these cells secrete soluble protein.	21208193
ARCN1 gene, Inflammation, Depression, CTCAE, Fatigue	Altered Intercellular Communication	Biomarkers of systemic inflammation and depression and fatigue in moderate clinically stable COPD.	21208443
Inflammation, Depression, CTCAE	Altered Intercellular Communication	It has recently been suggested that depression may be the result of systemic inflammation.	21208443
ARCN1 gene, Inflammation, Depression, CTCAE, Fatigue	Altered Intercellular Communication	We aimed to explore the association between systemic inflammation and symptoms of depression and fatigue in patients with mainly moderate and clinically stable COPD using a range of inflammatory biomarkers, 2 depression and 2 fatigue scales.	21208443
Inflammation	Altered Intercellular Communication	Hence, there is a regulatory system in Tenascin expression and plays a vital role in embryogenesis, tumerogenesis and inflammation in remodelling the stroma for cell migration and also for healing.	21208610
Inflammation, Infectious Endophthalmitis	Altered Intercellular Communication	Excessive inflammation, particularly in the early post-operative phase, should be regarded as infective endophthalmitis.	21209518
Sepsis, Euthyroid Sick Syndromes	Altered Intercellular Communication	There is ongoing controversy as to whether hormonal changes of the euthyroid sick syndrome are predictors of poor outcome in sepsis and critical illness.	21210252
Airway structure	Altered Intercellular Communication	Genes in the IL-1 and TNF-a/nuclear factor-kB pathways were overexpressed and correlated with clinical parameters and neutrophilic airway inflammation.	21211650
allergic inflammation	Altered Intercellular Communication	There is a reduction in AMP PC threshold but not histamine PC threshold during the pollen season, indicating that AMP is a more sensitive indicator of allergic inflammation.	21211652
Inflammation, Cutis Laxa	Altered Intercellular Communication	Governed by macrophages, the pathogenesis of DC may begin with subclinical inflammation leading to elastolysis and secondary lymphostasis.	21211847
Arterial calcification, HD Term Type, Amputation of leg through tibia and fibula, CLU protein, human, Whole-Body Irradiation	Altered Intercellular Communication	Furthermore, arterial calcification of below-knee arteries and micro-inflammation represented as CRP were the independent associating factors for low TBI, which was the independent associating factor for PAD and CLI in HD patients.	21211928
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Based on previously published anecdotes, the hypothesis is that conjunctiva shows increased inflammation and fibrosis.	21212848
Inflammation, Fibrosis Assessment, Mast cell infiltration	Altered Intercellular Communication	Main outcome measures were degree of inflammation and fibrosis, mast cell infiltration, and fibroblast count.	21212848
Inflammation, Mast cell infiltration	Altered Intercellular Communication	The Mann-Whitney test showed no difference between groups in inflammation (P=.17), relative blue intensity (P=.11), degree of mast cell infiltration (P=.61), and fibroblast count (P=.45).	21212848
Inflammation, Thyroid associated opthalmopathies	Altered Intercellular Communication	While there is a trend toward higher inflammation in the study group, the superior palpebral conjunctiva of patients with thyroid-related orbitopathy is largely spared from autoimmune changes.	21212848
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Growing evidence has shown that inflammation plays crucial roles in the development of coronary artery disease (CAD).	21214401
Inflammation	Altered Intercellular Communication	Therefore, recognition of this combination of peripheral and central nervous inflammation early is important for determining prognoses and perhaps initial treatment.	21215910
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Formylpeptide receptor (FPR1) is involved in inflammation, which is important in the pathogenesis of diverse conditions, including common diseases and cancers.	21216225
Rheumatoid Arthritis, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Lipid paradox in rheumatoid arthritis: the impact of serum lipid measures and systemic inflammation on the risk of cardiovascular disease.	21216812
Inflammation, Cardiovascular Diseases, Refractory anemias, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Rheumatoid Arthritis	Altered Intercellular Communication	To examine the impact of systemic inflammation and serum lipids on cardiovascular disease (CVD) in rheumatoid arthritis (RA).	21216812
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Two specimens (50%) of the heart showed areas of mature fat cells in the myocardium, without associated inflammation, without associated fibrosis, without entrapped myocardial cells and without a capsule.	21217088
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Chronic inflammation has been implicated in the etiology of colorectal cancer (CRC), but epidemiologic findings on the association between circulating inflammatory markers and CRC risk are inconsistent.	21217085
Inflammation	Altered Intercellular Communication	Albumin was included with a negative sign, because its concentration decreases with greater inflammation.	21217085
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Proportional hazard models were used to estimate the HR and 95% CI of CRC in relation to each individual marker and the inflammation z-score.	21217085
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	After multivariate adjustment, for the highest versus lowest quartile, there was a statistically significant positive association of CRC risk with fibrinogen: HR = 1.50 (95% CI, 1.05-2.15), P = 0.03; inflammation z-score: HR = 1.65 (95% CI, 1.15-2.35), P = 0.01; and CRP: HR = 1.97 (95% CI, 1.13-3.43, P = 0.02.	21217085
Vasculitis, Colorectal Carcinoma	Altered Intercellular Communication	These findings indicate that greater levels of fibrinogen, CRP, and blood inflammation z-score are associated with increased CRC risk.	21217085
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The study provides further evidence that precancer inflammation may contribute to CRC etiology.	21217085
Inflammatory abnormality of the eye	Altered Intercellular Communication	However, ocular inflammation can occur in predisposed individuals.	21217412
Inflammation	Altered Intercellular Communication	This inflammation is referred to as immune-recovery uveitis.	21217412
Macular Edema, Cystoid, Inflammation, HIV, Unspecified visual loss	Altered Intercellular Communication	Cystoid macular edema (CME) is a complication that can result from this inflammation and is emerging as a major cause of visual loss in human immunodeficiency virus (HIV)-infected patients.	21217412
Inflammatory abnormality of the eye, Thickened, Cicatrization	Altered Intercellular Communication	Retinal examination revealed bilateral areas of peripheral scarring from presumed past ocular inflammation and thickening and irregularity at each macula.	21217412
TNF protein, human, Inflammation, Radiculopathy, Pain Distress Question	Altered Intercellular Communication	TNF-a is a known mediator of inflammation and pain associated with radiculopathy and IVD degeneration.	21217452
Inflammation	Altered Intercellular Communication	These results suggest this sTNFR to be a potent TNF antagonist with potential to attenuate inflammation in IVD pathology.	21217452
Sarcoidosis, Neoplasms, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Based on the suspicion of spinal tumor, spinal cord biopsy was performed, and the histology revealed multinucleated giant cells, lymphocytes and aggregated histiocytes within granulomatous inflammation, consistent with non-caseating granuloma seen in sarcoidosis.	21218047
Inflammation	Altered Intercellular Communication	These findings suggest that periodontal inflammation in AMI patients might be associated with higher MMP-8-values compared to the healthy controls.	21219642
Inflammation, Electrocardiogram: myocardial infarction (finding), Periodontal Diseases	Altered Intercellular Communication	The acute myocardial infarction seems to influence the degree of periodontal inflammation, thus the measurement of the gingival crevicular fluid MMP8 levels seems to be a helpful biochemical test to obtain information about the severity of the periodontal disease.	21219642
Inflammation, Dysbiosis	Altered Intercellular Communication	Shifts in the composition of resident bacteria have been postulated to drive the chronic inflammation seen in both diseases (the "dysbiosis" hypothesis).	21219646
Inflammation	Altered Intercellular Communication	We propose a complement-driven immune response which may contribute to the progression of the inflammation and ultimately lead to even more motor neuron injury.	21220013
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Chronic inflammation play an important role on abdominal aortic aneurysms (AAA) formation.	21220372
Inflammation	Altered Intercellular Communication	However, it is not known whether this increase is linked to its involvement in alveolar epithelium injury or in systemic inflammation.	21220996
Inflammation, Diverticular Diseases	Altered Intercellular Communication	Absence of mucosal inflammation in uncomplicated diverticular disease.	21221786
Inflammation, Diverticulum, Diverticular Diseases	Altered Intercellular Communication	Our purpose was to evaluate the presence of inflammation in the colonic mucosa of patients with symptomatic uncomplicated diverticular disease compared with subjects without diverticula.	21221786
Inflammation, Diverticular Diseases	Altered Intercellular Communication	Even if based on a small number of patients, the study demonstrates the absence of inflammation in the mucosa of subjects affected by uncomplicated diverticular disease.	21221786
Inflammation, Atrophic, Metaplasia	Altered Intercellular Communication	The degree of activity (P=0.006) and inflammation (P=0.007) improved significantly after four weeks of successful H. pylori eradication treatment, whereas the degree of atrophy, metaplasia, and Cdx2 expression did not.	21221798
Airway structure, Asthma	Altered Intercellular Communication	However, effects of obesity/adiposity on airway inflammation are not well known in subjects without asthma.	21222563
Airway structure, Asthma	Altered Intercellular Communication	We assessed whether fractional exhaled nitric oxide (FeNO), a marker of eosinophilic airway inflammation, was associated with obesity/adiposity in nonasthmatic healthy adults.	21222563
Inflammation, Bladder Detrusor Muscle	Altered Intercellular Communication	The mRNA expression of a1-AR subtypes in bladder detrusor and posterior urethra was significantly higher in the inflammation group than in the control group (P<0.05).	21223784
Inflammation, Bladder Detrusor Muscle	Altered Intercellular Communication	While the mRNA expression of a1-AR subtypes in the bladder detrusor and posterior urethra was significantly lower in the inflammation group than in the control group (P<0.05).	21223784
Inflammation	Altered Intercellular Communication	Biochemical coagulation and inflammation parameters were measured pre-, peri-, and postoperatively.	21224820
Inflammation, Ventricular failure	Altered Intercellular Communication	Preoperative evaluation of markers of inflammation and neurohumoral activation may provide additional information for predicting right ventricular failure after implantation of an LVAD.	21225395
Granulomatous inflammation	Altered Intercellular Communication	Neuropathological examination of the removed material showed typical granulomatous inflammation with characteristic infiltrate of lymphocytes, epithelioid macrophages and Langhans-type multi-nucleated giant cells.	21225513
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation plays a prominent role in Alzheimer disease (AD) pathogenesis.	21225514
Communicable Diseases, Anemia, Pernicious, Inflammation, Epstein-Barr virus associated gastric carcinoma	Altered Intercellular Communication	Both chronic inflammation and the lack of stomach acid may influence the likelihood of EBV infection of the neoplastic gastric epithelium, but the prevalence of EBV-associated gastric carcinoma among patients with pernicious anemia is unknown.	21225628
Tumor necrosis, Hypoxia	Altered Intercellular Communication	Tumor necrosis factor blocking therapy alters joint inflammation and hypoxia.	21225682
Tumor necrosis, Arthritis, Inflammation, Hypoxia	Altered Intercellular Communication	To examine the effect of tumor necrosis factor (TNF) blocking therapy on hypoxia in vivo, macroscopic and microscopic inflammation, and magnetic resonance imaging (MRI) results in patients with inflammatory arthritis.	21225682
Inflammation	Altered Intercellular Communication	Changes are strongly associated with changes in macroscopic and microscopic measures of joint inflammation and MRI improvement.	21225682
Inflammation, Hypoxia	Altered Intercellular Communication	These data further strengthen the concept that hypoxia is an important event driving synovial inflammation.	21225682
Osteitis	Altered Intercellular Communication	NOE must be considered in all patients with temporal bone inflammation, especially those with risk factors and those that fail to improve with more conservative measures.	21225805
Inflammation, Chronic inflammatory disorder	Altered Intercellular Communication	To determine whether combined higher interleukin-6 (IL-6) and C-reactive protein (CRP) levels are associated with lower pulmonary function levels in older women, accounting for chronic inflammatory diseases, physical function, and other factors associated with inflammation.	21226682
Inflammation, Electrocardiogram: myocardial infarction (finding), Obesity, Atherosclerosis	Altered Intercellular Communication	Association with adipokines favours the concept that AHSG is involved in atherosclerosis more likely through metabolic pathways (insulin resistance, obesity and adipocyte dysfunction) than by inflammation in patients with post-myocardial infarction.	21226708
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Decreased adiponectin and increased inflammation expression in epicardial adipose tissue in coronary artery disease.	21226932
Sepsis, Inflammation	Altered Intercellular Communication	Procalcitonin is a useful marker to rule out sepsis and systemic inflammation in the ED.	21228358
Inflammation	Altered Intercellular Communication	The device was functioning intermittently, and no evidence of local or systemic inflammation was observed.	21228592
Communicable Diseases, Inflammation, Necrosis	Altered Intercellular Communication	The intraoperative findings showed inflammation and necrosis of the right m. abductor pollicis brevis, but no infection with pus.The patient accused the first hospital of irrigating the tissue of his right hand with Octenisept(r).	21229225
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Oxidation and inflammation are linked processes playing an important role in the development and progression of coronary artery disease (CAD).	21231776
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	The relation between oxidation and inflammation markers with myocardial ischemia is still controversial.	21231776
atherosclerotic, Lupus Erythematosus, Systemic	Altered Intercellular Communication	The decreased CD36 and CD163 expression observed in atherosclerotic and SLE patients, respectively, suggest that these inflammatory conditions modulate these receptors differentially.	21231894
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Increased inflammation in more highly addicted current smokers could influence the CT lung density distribution, which may influence genetic association studies of emphysema phenotypes.	21232152
Inflammation, Coronary Arteriosclerosis, Angina Pectoris	Altered Intercellular Communication	Clinical characteristics, vascular function, and inflammation in women with angina in the absence of coronary atherosclerosis: the Dallas Heart Study.	21232706
Inflammation	Altered Intercellular Communication	Cyanate is formed in vivo by breakdown of urea and at sites of inflammation by the phagocyte protein myeloperoxidase.	21235354
Inflammation, Inflammatory disorder	Altered Intercellular Communication	TGF-bs and their receptors also have an important role in modulation of skin inflammation, proliferation of epidermal cells, and wound healing, and they have been implicated in different types of skin inflammatory disorders.	21235789
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	Evidence of neutrophil functional defect despite inflammation in stable cirrhosis.	21236309
Inflammation, Phagocytes, Liver Cirrhosis	Altered Intercellular Communication	In patients with compensated cirrhosis and apparently normal neutrophil function, the 'skin-window' study disclosed a severe phagocytic defect at the site of inflammation.	21236309
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Activated factor XI and tissue factor in chronic obstructive pulmonary disease: links with inflammation and thrombin generation.	21236471
ARCN1 gene, Inflammation	Altered Intercellular Communication	This is the first study to show that active FXIa and TF are present in stable COPD patients, who exhibit enhanced systemic inflammation and thrombin generation.	21236471
Inflammation, Endothelial dysfunction, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation, endothelial dysfunction and metabolic pathways provide possible links between the inflammatory and hypofibrinolytic states in atrial fibrillation.	21237502
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	However, a positive association between degree of steatosis and hs-CRP was observed (p<0.05) and this effect remained significant after adjusting for BMI, lobular inflammation, hepatocyte ballooning, and fibrosis.	21238518
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Hemoglobin, erythropoietin and systemic inflammation in exacerbations of chronic obstructive pulmonary disease.	21238904
Inflammation, Anemia	Altered Intercellular Communication	Systemic inflammation may represent a possible cause of anemia.	21238904
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	We aimed to determine whether systemic inflammation, which is usually up-regulated during exacerbations of COPD (ECOPD) is associated with low hemoglobin levels expressing erythropoietin resistance.	21238904
Inflammation	Altered Intercellular Communication	Role of nutritional status and inflammation in higher survival of African American and Hispanic hemodialysis patients.	21239093
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Studies show that inflammation can contribute to an increase in resting energy expenditure in patients with chronic kidney disease; however, findings about total energy expenditure (TEE) have not been reported.	21239181
Inflammation	Altered Intercellular Communication	Our findings suggest that patients with inflammation have a lower TEE when compared with healthy subjects and patients without inflammation.	21239181
Inflammation, Malnutrition	Altered Intercellular Communication	Patients new to dialysis with laboratory-based evidence of malnutrition and/or inflammation are likely to report lower levels of physical activity.	21239185
methyldopa, Inflammation	Altered Intercellular Communication	Nuclear receptors (NRs), including peroxisome proliferator-activated receptor and liver X receptor, have been identified as key regulators of physiological pathways such as lipid metabolic dysregulation and inflammation, pathways that may also be involved in development of AMD.	21239617
Inflammation, Reperfusion Injury	Altered Intercellular Communication	Endothelial dysfunction accompanied by increased oxidative stress and inflammation with aging may predispose older arteries to greater ischemia-reperfusion (I/R) injury.	21239631
Inflammation, Anemia	Altered Intercellular Communication	Prevalence of 25-hydroxyvitamin D deficiency in subgroups of elderly persons with anemia: association with anemia of inflammation.	21239700
Inflammation, Anemia	Altered Intercellular Communication	The prevalence of vitamin D deficiency was 33.3% in the nonanemic population, 56% in anemia of inflammation (AI; P = .008), and 33.0% in unexplained anemia (P = .55).	21239700
Arterial Stiffness, Rheumatoid Arthritis, Chronic inflammation	Altered Intercellular Communication	Early prediction of increased arterial stiffness in patients with chronic inflammation: a 15-year followup study of 108 patients with rheumatoid arthritis.	21239744
Disease	Altered Intercellular Communication	Inflammation early in the RA disease course was associated with increased AIx and PWV after 15 years.	21239744
Cartilage destruction, Inflammation, polychondritis	Altered Intercellular Communication	Cartilage destruction in polychondritis is induced not only by perichondral inflammation, but also by intrinsic factors expressed in chondrocytes themselves, including certain kinds of proteolytic enzymes and apoptosis.	21239745
Inflammation, Autoimmune Diseases, Communicable Diseases, Anemia, Chronic disease	Altered Intercellular Communication	Inflammation arising from various etiologies, including infection, autoimmune disorders, chronic diseases, and aging, can promote anemia.	21239806
Inflammation, Anemia	Altered Intercellular Communication	The anemia of inflammation (AI) is most often normocytic and normochromic and is usually mild.	21239806
Nutritional Deficiency, Inflammation, Anemia	Altered Intercellular Communication	Although many anemic elderly patients can be diagnosed with nutritional deficiency, anemia of chronic inflammation or comorbid diseases that explain their decreased hematocrit, the etiology of anemia in a significant fraction remains obscure.	21239805
Inflammation, Anemia, hepcidin	Altered Intercellular Communication	Consequently, genetic variation in the expression of these proinflammatory cytokines may influence the development of anemia in elderly patients, both through induction of hepcidin expression (anemia of inflammation) and through cytokine suppression of erythroid colony formation.	21239805
Inflammation, Ischemic stroke	Altered Intercellular Communication	Antihypertensive drugs and inflammation in acute ischemic stroke as a predictor factor of future cardiovascular mortality.	21240546
Inflammation, Corneal Opacity	Altered Intercellular Communication	Confocal scan also disclosed intense haze and inflammation at the interface and clusters of hyperreflective round structures resembling epithelial cells within the interface area.	21240860
Adult Hepatocellular Carcinoma	Altered Intercellular Communication	Usefulness of a modified inflammation-based prognostic system for predicting postoperative mortality of patients undergoing surgery for primary hepatocellular carcinoma.	21240991
Acute and chronic inflammation	Altered Intercellular Communication	Urease activity or H. pylori density in the antrum was significantly correlated with chronic active inflammation; in contrast, this correlation was not found in the gastric body.	21241408
Airway structure, ARCN1 gene	Altered Intercellular Communication	Airway inflammation and mannitol challenge test in COPD.	21241520
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Eosinophilic airway inflammation has successfully been used to tailor anti-inflammatory therapy in chronic obstructive pulmonary disease (COPD).	21241520
Respiratory Hypersensitivity, AHR wt Allele, Airway structure	Altered Intercellular Communication	Airway hyperresponsiveness (AHR) by indirect challenges is associated with airway inflammation.	21241520
Airway structure	Altered Intercellular Communication	In mild-moderate COPD mannitol hyperresponsiveness is associated with biomarkers of airway inflammation.	21241520
ARCN1 gene, Eosinophilic inflammation	Altered Intercellular Communication	The high specificity of mannitol challenge suggests that the test is particularly suitable to exclude eosinophilic airways inflammation, which may facilitate individualized treatment in COPD.	21241520
Cataract, Intraocular inflammation	Altered Intercellular Communication	To report cases of intraocular inflammation after intracameral injection of a very high dose of cefuroxime at the end of uneventful cataract surgery.	21241909
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	While MetS and specific cytokine patterns associated with arterial aging, the increases in arterial stiffness and thickness are greater when both MetS and higher cytokine levels are present, suggesting a possible synergistic effect of MetS and inflammation on the arterial wall.	21241986
palladium, Inflammation	Altered Intercellular Communication	Using more stringent remission criteria resulted in reduced signs and symptoms of inflammation, but the percentage of joints with PD activity was not reduced, even in those without signs or symptoms.	21242236
Inflammation	Altered Intercellular Communication	These data suggest that clinical criteria are sufficiently insensitive to detect low but clinically relevant levels of inflammation accurately.	21242236
Inflammation, Metabolic Syndrome X, Osteoporosis, Obesity, MS gene	Altered Intercellular Communication	Metabolic syndrome (MS) has 2 conflicting factors: obesity known to be protective against osteoporosis and an inflammation that activates bone resorption.	21242648
Inflammation, Obesity	Altered Intercellular Communication	Inflammation might have a more important role in BMD than obesity in the postmenopausal women.	21242648
Inflammation, Malnutrition	Altered Intercellular Communication	Malnutrition and inflammation determine prognosis of patients with CRS type 4.	21242681
HD Term Type, Malnutrition, Myocardial Ischemia, Inflammation	Altered Intercellular Communication	The poor survival rate of incident HD patients with a medical history of ischemic heart disease was predicted by malnutrition and inflammation at the start of HD.	21242681
Inflammation	Altered Intercellular Communication	An increased percentage of pro-inflammatory CD14(+)CD16(+) monocytes might contribute to inflammation in hemodialysis (HD) patients.	21242682
HD Term Type, Inflammation	Altered Intercellular Communication	Increased pro-inflammatory monocytes are likely to contribute to inflammation in HD patients, and beneficial effect of on-line HDF might be partially mediated by modulating the inflammatory response.	21242682
Inflammation, Hernia	Altered Intercellular Communication	The clinical presentation depended on the inflammation extension inside the hernia sac and the presence or not of peritoneal contamination.	21243805
Gingivitis, Dental Plaque	Altered Intercellular Communication	Preterm children had more plaque, a higher degree of gingival inflammation, and more behaviour-management problems than controls.	21244509
Inflammation, Hyperparathyroidism, Dyslipidemias, Pathology	Altered Intercellular Communication	On-line high-efficiency HDF resulted in enhanced removal and lower basal levels of small, medium-sized and protein-bound solutes, which are markers or causative agents of uraemic pathologies, mainly inflammation, secondary hyperparathyroidism and dyslipidaemia.	21245130
Inflammation, atherosclerotic	Altered Intercellular Communication	A state of low-grade inflammation accompanies the pathogenesis of atherosclerotic events.	21245598
Inflammation, Erosion lesion, Fever, CTCAE, Bursitis, Inflammatory	Altered Intercellular Communication	We report the clinical case of a 76 years-old woman with a subacute trochanteric inflammatory pain with low-grade fever and laboratory markers of acute inflammation, associated with the ultrasonographic evidence of bursitis and radiologic evidence of femoral erosions, that resolved after intravenous antibiotherapy.	21245818
Inflammation, Reactive systemic amyloidosis	Altered Intercellular Communication	Secondary amyloidosis (SA) results of tissue deposition of an acute phase reactant protein produced by chronic inflammation.	21245821
Inflammation	Altered Intercellular Communication	The variable FDG uptake in SPNs and mediastinal LNs are associated with the high prevalence of inflammation/infection within the chest.	21247262
Inflammation	Altered Intercellular Communication	Similar SUVmax thresholds however may exist for extrathoracic regions where the prevalence of inflammation/infection is low.	21247262
Inflammation, Calcinosis	Altered Intercellular Communication	Viral and bacterial patterns induce TLR-mediated sustained inflammation and calcification in aortic valve interstitial cells.	21247641
Inflammation, CDIPT gene	Altered Intercellular Communication	Patients with PIS showed significant greater changes of inflammation marker levels, including hs-CRP and IL-6, as compared with the non-PIS group.	21248083
Inflammation, Fibrosis Assessment, Hepatitis, Chronic	Altered Intercellular Communication	To determine whether mean and entropy apparent diffusion coefficient (ADC) values obtained at diffusion-weighted (DW) magnetic resonance (MR) imaging can help detect and stage histopathologic liver fibrosis and grade inflammation activity in patients with chronic hepatitis C. This retrospective study was approved by the institutional review board, and the requirement for informed consent was waived.	21248235
Inflammation, Chronic Kidney Diseases, Nephritis, Lupus Erythematosus	Altered Intercellular Communication	As systemic inflammation is also thought to contribute directly to the progression of chronic kidney disease (CKD), we assessed this risk in patients with lupus, with and without a diagnosis of nephritis, and also identified modifiable risk factors.	21248713
Inflammation, Refractory anemias, Rheumatoid Arthritis, Functional Disability, deformities qualifier	Altered Intercellular Communication	Rheumatoid arthritis (RA) is characterized by inflammation of the synovial membrane, which can lead to deformities and functional disability.	21249408
Inflammation, Tooth structure, Ankylosis	Altered Intercellular Communication	At the 24 months follow-up the root showed no radiographic signs of inflammation, resorption or ankylosis, and the function of the replanted tooth was fully maintained.	21250776
Inflammation	Altered Intercellular Communication	Extracellular matrix remodeling by cathepsins play an important role in many conditions associated with inflammation.	21250859
Granulomatous inflammation	Altered Intercellular Communication	In addition to poorly defined granulomatous inflammation, leprosy-like sarcoidal and palisaded granulomatous inflammation has been documented in literature reports of lues.	21251035
Inflammation, Depression, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	Tertiary outcomes will be biochemical markers reflecting common pathophysiological processes of insulin resistance, inflammation and oxidative damage that are assumed to be intertwined in both diabetes and depression.	21251307
Inflammation, Carcinogenesis	Altered Intercellular Communication	Inflammation appears to be important in lung carcinogenesis among smokers, but its role among never-smokers is not well established.	21252117
Inflammation, millicurie	Altered Intercellular Communication	Systemic inflammation is associated with MCI and its subtypes: the Sydney Memory and Aging Study.	21252552
Presenile dementia, Inflammation, Impaired cognition, millicurie	Altered Intercellular Communication	Raised low-grade systemic inflammation has been associated with dementia, and preliminary studies suggest an association with mild cognitive impairment (MCI).	21252552
Inflammation, millicurie	Altered Intercellular Communication	Our findings suggest an association between specific inflammatory markers and MCI subtypes, highlight sex differences in the association with MCI, and point to a discrete impact of systemic inflammation on cognition.	21252552
Inflammation, Intraductal Hyperplasia, Syringofibroadenoma, Acanthoma, Clear Cell, Traumatic injury, Histogenic Process	Altered Intercellular Communication	Because a reactive histogenesis has been postulated for both eccrine syringofibroadenoma and clear cell acanthoma, this case could represent a morphologically biphasic pattern of epidermal and ductal hyperplasia as a consequence of the stasis-induced chronic inflammation coupled with the footwear-induced chronic trauma.	21252636
Inflammation, biloma	Altered Intercellular Communication	Coagulation of the transition plan in a context of mutation of the prothrombin gene and inflammation induced biloma were the likely predisposing conditions.	21253403
Inflammation	Altered Intercellular Communication	Resistance training may assist in maintaining or improving muscle volume and reducing low-grade inflammation.	21253481
malignant disease, Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Haptoglobin (Hp) is produced as an acute phase reactant during inflammation, infection, malignant diseases, and several cancers.	21253648
Arteritis, Aortitis	Altered Intercellular Communication	US is a quick and noninvasive test to detect inflammation of temporal artery, and FDG-PET is very helpful for early diagnosis of aortitis in GCA.	21253802
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Thus, TLR4, CD14, and NF-kBp65 were upregulated significantly in UC, to an extent that reflects the degree of inflammation and thereby might contribute to the occurrence and development of UC.	21253969
Acute pyelonephritis, Inflammation	Altered Intercellular Communication	In experiment on 40 white rats with acute pyelonephritis HBO decreased inflammation in renal tissue.	21254635
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Treatment with an oral direct thrombin inhibitor decreases platelet activity but increases markers of inflammation in patients with myocardial infarction.	21255134
Inflammation, Squamous cell carcinoma, Carcinoma	Altered Intercellular Communication	Inflammation is associated with the pathogenesis of carcinoma, including squamous cell carcinoma of the bladder.	21255800
Inflammation, Chronic pain, Depression, CTCAE	Altered Intercellular Communication	Patients with CIAP usually suffer from chronic pain and associated depression, both of which have been proposed to cause insulin resistance (IR) by such mechanisms as a sustained increase in the corticosteroids and catecholamines, and chronic low grade inflammation.	21255940
Granulomatous inflammation, Fibrosis Assessment, Dysplasia	Altered Intercellular Communication	Histologic assessment always revealed ureteral fibrosis and in 2 cases accompanying granulomatous inflammation and dysplasia.	21256392
Inflammation	Altered Intercellular Communication	In conclusion, higher NLR, an emerging marker of inflammation, is associated with an increased risk for long-term mortality in patients admitted with ADHF.	21257011
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	There are increased neutrophils in the lungs of patients with chronic obstructive pulmonary disease (COPD), but it is unclear if this is due to increased inflammatory signal or related to the inherent behavior of the neutrophils.	21257786
Inflammation	Altered Intercellular Communication	She was diagnosed to have chronic IC, based upon the cystoscopic biopsy finding of chronic inflammation in the bladder wall.	21258795
Inflammation	Altered Intercellular Communication	However, in daily clinical practice ultrasound (US) imaging with Doppler information is more versatile and often used for fast and dynamic assessment of joint inflammation.	21259184
Refractory anemias, Inflammation, Edema of bone marrow	Altered Intercellular Communication	Within limits, the OMERACT RAMRIS scores of inflammation in RA patients (bone marrow oedema and synovial enhancement) are comparable to the US colour-fraction measurements using a high-end US scanner.	21259184
Inflammation	Altered Intercellular Communication	Both imaging modalities detect inflammation although showing different aspects of the inflammatory process in the wrist joint.	21259184
Airway structure, Asthma, Zinc deficiency	Altered Intercellular Communication	Mouse models of asthma show that zinc deficiency is associated with airway inflammation (AI), which is attenuated by zinc supplements.	21261783
Celiac Disease, Inflammation, Myocardial Ischemia, Cessation of life	Altered Intercellular Communication	Celiac disease (HR, 1.22; 95% CI, 1.06 to 1.40) and inflammation (HR, 1.32; 95% CI, 1.14 to 1.52) were both associated with death resulting from IHD, whereas latent CD was not (HR, 0.71; 95% CI, 0.34 to 1.50).	21262996
Gastrointestinal inflammation	Altered Intercellular Communication	Individuals with CD or small intestinal inflammation are at increased risk of incident IHD.	21262996
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	It has been reported that proinflammatory cytokine dysregulation and neutrophil-dominated inflammation are the main causes of morbidity in cystic fibrosis (CF).	21263071
Intraocular inflammation, Endophthalmitis, CTCAE, diabetic	Altered Intercellular Communication	The possibility of K. pneumoniae endogenous endophthalmitis should be suspected in diabetic patients presenting with intraocular inflammation.	21264489
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Glucocorticoids (GCs) may improve RF in MM by (1) rapid reduction of paraprotein production, (2) lessening inflammation and fibrosis in renal parenchyma, and (3) decreasing serum calcium level.	21264915
Inflammation	Altered Intercellular Communication	Donor-reactive immune cells seem to have cross-reacted with unknown pathogens on the skin and contributed to inflammation.	21265283
Refractory anemias, Inflammation	Altered Intercellular Communication	We examined the impact of oral ingestion of a pre-biotic dPP supplement active compound (AC) on serum glycosylation and clinical variables associated with inflammation and general health in patients with RA.	21266447
Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	An inflammation-based prognostic score (mGPS) predicts cancer survival independent of tumour site: a Glasgow Inflammation Outcome Study.	21266974
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus	Altered Intercellular Communication	C-reactive protein (CRP), a marker of inflammation, is associated with diabetes and CVD.	21267537
Inflammation, Autoimmune Diseases, polychondritis, Traumatic injury, Retinitis Pigmentosa	Altered Intercellular Communication	Relapsing polychondritis (RP) is an autoimmune disease characterized by inflammation and destruction of all type of body cartilage, and the cartilage trauma may be a trigger of the disease in a susceptible person.	21267573
Inflammation	Altered Intercellular Communication	Serum and organ-associated anti-hemoglobin humoral autoreactivity: association with anti-Sm responses and inflammation.	21268022
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	The release of hemoglobin (Hb) occurs in some infectious and autoimmune diseases characterized by inflammation.	21268022
Inflammation, Uveitis	Altered Intercellular Communication	[Frequency of classified forms in endogenous uveitis considering the anatomical location of the inflammation].	21268816
Inflammation, Uveitis	Altered Intercellular Communication	To investigate the frequency of classified forms in endogenous uveitis in Asahikawa Medical College considering the anatomical location of the inflammation.	21268816
Inflammation, Uveitis	Altered Intercellular Communication	We reviewed medical charts of the patients' age at disease onset, unilateral or bilateral uveitis, anatomical location of inflammation and diagnosis of classified form of uveitis.	21268816
Inflammation, Gastrointestinal Neoplasms	Altered Intercellular Communication	Oxygen free radicals and their reactive derivatives participate in formation of chronic inflammation states, which facilitate development of gastrointestinal tract tumors.	21268915
Inflammation, Demographics Domain, ETV3 wt Allele	Altered Intercellular Communication	Valsartan administration lowered increased levels of chronic inflammation in both HT Mets patients with DM and in those without DM.	21269062
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Fecal calprotectin (FC) is a non-invasive marker of gastrointestinal inflammation with advocated diagnostic precision in distinguishing inflammatory bowel disease (IBD) from non-IBD diagnoses.	21269246
Inflammation, Migraine Disorders, GDC Comorbidity Terminology, Obesity, Pain Disorder	Altered Intercellular Communication	Obesity, comorbid with pain disorders including migraine, shares common pathophysiological characteristics including systemic inflammation, and derangements in adipose-tissue derived cytokines.	21269300
Neuronal degeneration, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) is associated with neuronal degeneration, synaptic loss and deficits in multiple neurotransmitter systems.	21269332
Retinal Vein Occlusion	Altered Intercellular Communication	Role of inflammation-related gene polymorphisms in patients with central retinal vein occlusion.	21269700
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Diabetes is accompanied with a chronic low-grade inflammation, which may in part be mediated by endotoxins derived from Gram-negative bacteria.	21270197
Inflammation, Metabolic Diseases, Endotoxemia, Diabetes Mellitus	Altered Intercellular Communication	Both prevalent and incident diabetes were associated with endotoxemia, which may link metabolic disorders to inflammation.	21270197
Inflammation, Hyperglycemia	Altered Intercellular Communication	Responses to critical illness, such as excessive inflammation and hyperglycemia, may trigger detrimental chain reactions that damage cellular proteins and organelles.	21270330
Inflammation, Atherosclerosis	Altered Intercellular Communication	The reason is unknown, but chronic inflammation may predispose to atherosclerosis.	21272803
Inflammation, Malnutrition, Albuminuria, Hypoalbuminemia	Altered Intercellular Communication	Hypoalbuminaemia is more strongly associated with inflammation than with albuminuria and malnutrition.	21273106
Sleep-Disordered Breathing, Glucose Intolerance (disease), Inflammation, Hypoxemia	Altered Intercellular Communication	As sleep-disordered breathing is associated with disorders of glucose metabolism, it was hypothesised that recurrent episodes of hypoxaemia during sleep, and sleep disruption, would be associated with inflammation and glucose intolerance in CF.	21273357
Infectious Lung Disorder, allergic inflammation	Altered Intercellular Communication	Mice were exposed intranasally to formalin-killed Mycobacterium avium from a patient with hot tub lung (HP strain) or chronic pulmonary infection (non-HP strain), and bronchoalveolar lavage fluids and lung tissues were evaluated for allergic inflammation.	21273385
Pneumonitis	Altered Intercellular Communication	Dead M. avium HP strain, but not non-HP strain, elicited marked HP-like pulmonary inflammation in wild-type mice.	21273385
hormone deficiency, Craniofacial Abnormalities	Altered Intercellular Communication	Presenting this second case of Melnick-Needles syndrome associated with growth hormone deficiency, we suggest that this association may be coincidental, but that it may also be a consequence of craniofacial abnormalities or an independent component of the disorder.	21274303
Communicable Diseases, Noncommunicable Diseases, Inflammation	Altered Intercellular Communication	Intravitreal bevacizumab may result in intraocular inflammation of infectious and non-infectious etiology.	21275601
Intraocular inflammation, Infectious Endophthalmitis, Uveitis	Altered Intercellular Communication	Existing reports of intraocular inflammation following intravitreal bevacizumab range from uveitis to infectious endophthalmitis.	21275601
Communicable Diseases, Necrosis, Granulomatous inflammation	Altered Intercellular Communication	Histological examination of a skin biopsy specimen demonstrated granulomatous inflammation with a necrotic centre; screening for an infectious aetiology was negative.	21276459
Postoperative Hemorrhage	Altered Intercellular Communication	Concerning factors affecting postoperative hemorrhage, significant differences were seen in relation to surgical tooth extraction (P = .008) and acute inflammation findings (P = .007).	21277059
Airway structure, Respiration Disorders, Bronchial Hyperreactivity, Obstruction	Altered Intercellular Communication	Asthma is a chronic respiratory disease, characterised by airways inflammation, obstruction and hyperresponsiveness.	21277184
Airway structure	Altered Intercellular Communication	Exhaled NO and exhaled breath condensate (EBC) NO metabolites (nitrites and nitrates) measurements are non-invasive tools to assess airways inflammation.	21277184
Airway structure, Asthma	Altered Intercellular Communication	Our aim was to investigate the relationships between asthma control and the above-named biomarkers of airways inflammation.	21277184
Airway structure, Symptoms	Altered Intercellular Communication	This suggests that nitrates, but not nitrites or FENO, reflect an aspect of airways inflammation that is closer related to asthma symptoms.	21277184
Inflammation, Nasal congestion (finding), Daytime somnolence	Altered Intercellular Communication	This inflammation of the nose leads to nasal congestion and a reduction in sleep quality, resulting in daytime somnolence.	21277510
Cataract, Intraocular inflammation, Glaucoma, CTCAE, Ocular Hypertension	Altered Intercellular Communication	Main outcome measures were Snellen acuity, intraocular inflammation, adjunctive therapy, cataract, ocular hypertension, or glaucoma.	21277557
Behavioral and psychological symptoms of dementia, Inflammation	Altered Intercellular Communication	Chronic low-grade inflammation in elderly persons is associated with altered tryptophan and tyrosine metabolism: role in neuropsychiatric symptoms.	21277567
Inflammation	Altered Intercellular Communication	Recent data suggest that chronic low-grade inflammation, a fundamental characteristic of aging, plays a role.	21277567
Inflammation	Altered Intercellular Communication	In addition, inflammation was associated with increases in neopterin and nitrite levels and in phenylalanine concentrations at the expense of tyrosine.	21277567
Behavioral and psychological symptoms of dementia, Inflammation	Altered Intercellular Communication	These findings show that chronic low-grade inflammation in aging is associated with alterations in enzymatic pathways involved in monoamine metabolism and suggest that these alterations might participate in the pathophysiology of neuropsychiatric symptoms in elderly persons.	21277567
Inflammation, SPOP gene	Altered Intercellular Communication	Inflammation does not seem to play an important role in the pathogenesis of POP.	21277671
Inflammation, Chronic disease, Homeopathy	Altered Intercellular Communication	Low-grade inflammation in chronic diseases: an integrative pathophysiology anticipated by homeopathy?	21277692
Inflammation	Altered Intercellular Communication	Pro-inflammatory cytokines and their chronic effect - low-grade inflammation - have been associated with diverse chronic conditions.	21277692
Inflammation, Lupus Erythematosus	Altered Intercellular Communication	Growth arrest-specific protein 6 (Gas6) and its receptor Axl are known to regulate inflammation and may be implicated in lupus pathogenesis.	21278074
Inflammation, Dental Plaque	Altered Intercellular Communication	To elucidate the relation between the echolucent plaque on carotid ultrasound and acute inflammation on F-18 FDG carotid PET/CT.	21279492
Inflammation	Altered Intercellular Communication	Synovial inflammation in patients undergoing arthroscopic meniscectomy: molecular characterization and relationship to symptoms.	21279996
Inflammation, Wounds and Injuries	Altered Intercellular Communication	Accordingly, we sought to characterize synovial pathology in patients with traumatic meniscal injuries and determine the relationships between inflammation, meniscal and cartilage pathology, and symptoms.	21279996
Inflammation, Pain Distress Question	Altered Intercellular Communication	Synovial inflammation was present in 43% of the patients and was associated with worse preoperative pain and function scores, independent of age, sex, or cartilage pathology.	21279996
Degenerative polyarthritis, Inflammation, Wounds and Injuries, Pain Distress Question	Altered Intercellular Communication	Our findings indicate that in patients with traumatic meniscal injury undergoing arthroscopic meniscectomy without radiographic evidence of OA, synovial inflammation occurs frequently and is associated with increased pain and dysfunction.	21279996
Inflammation	Altered Intercellular Communication	Chemokines may contribute to the development of synovial inflammation in patients with meniscal pathology; they also represent potential therapeutic targets for reducing inflammatory symptoms.	21279996
Sjogrens Syndrome", Inflammation, physiopathological	Altered Intercellular Communication	MicroRNA expression profiles as biomarkers of minor salivary gland inflammation and dysfunction in Sjogren's syndrome.	21280008
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	We generated microRNA microarray profiles from the minor salivary glands of control subjects without Sjogren's syndrome (SS) and patients with SS who had low-grade or high-grade inflammation and impaired or normal saliva production, to identify microRNA patterns specific to salivary gland inflammation or dysfunction.	21280008
Inflammation, physiopathological	Altered Intercellular Communication	The predicted biologic targets of microRNA associated with inflammation or salivary gland dysfunction identified both overlapping and distinct biologic pathways and processes.	21280008
Inflammation, physiopathological	Altered Intercellular Communication	Distinct microRNA expression patterns are associated with salivary gland inflammation and dysfunction in patients with SS, and microRNA represent a novel group of potential biomarkers.	21280008
Granuloma, Inflammation, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Cytologic findings were categorized in to three groups as non-caseating granuloma, caseating granuloma and pyo-histiocytic inflammation.	21280429
Conjunctivitis	Altered Intercellular Communication	Conjunctival and eye lid inflammation was evident in 32.4% of people who had TT recurrence and it was associated with recurrence (OR 3.8, 95% CI: 2.7, 5.4, p < .005).	21280432
Conjunctivitis	Altered Intercellular Communication	Conjunctival and eye lid inflammation has been found to be strong risk factors for recurrence.	21280432
Communicable Diseases, Inflammatory abnormality of the eye, Congenital Abnormality	Altered Intercellular Communication	Exclusion criteria included: history of recent acute or chronic ocular inflammation or infection and lid surface abnormalities affecting lid function.	21281063
Eosinophilic granulomatosis with polyangiitis, Orbital Pseudotumor	Altered Intercellular Communication	A diagnosis of orbital inflammation in Churg-Strauss syndrome was suspected, and the immunosuppressive therapy was increased.	21281077
Inflammation	Altered Intercellular Communication	Inflammation as well as organ function are strongly associated with NT-proCNP serum concentrations.	21281508
Inflammation, Glycation End Products, Advanced, Coronary Artery Disease, Obesity	Altered Intercellular Communication	Obesity, a risk factor for coronary artery disease (CAD), is associated with inflammation and reactive oxygen species (ROS) production, while advanced glycation end-products, through their receptor (AGER or RAGE), play an important role on these processes.	21282351
Inflammation, Glaucoma, CTCAE, Traumatic injury, Corneal Neovascularization	Altered Intercellular Communication	Independent risk factors identified for decreased PKP survival were: 1 or more episodes of reversible rejection, active inflammation at PKP, preexisting corneal vascularization, intraoperative complications, small graft size (<= 7.25 mm), large graft size (>= 8.5 mm), preoperative glaucoma, and a preoperative diagnosis of regraft or trauma.	21282990
Temporomandibular Joint Disorders, Inflammation	Altered Intercellular Communication	In vivo confocal microscopy can detect subtle corneal changes in an advanced case of TMD, which may be signs of subclinical inflammation.	21282992
Inflammation, Doctor of Dental Medicine	Altered Intercellular Communication	The main outcome measures were IOP, postoperative changes in Descemet membrane detachment (DMD), healing of the surgical incision, and inflammation of the anterior chamber.	21282997
Cataract, Keratopathy, Inflammation, Corneal edema	Altered Intercellular Communication	Complications included increased intraocular pressure (9.7%), hypotony (2.4%), cataract (57.1%), silicone oil in anterior chamber (17%), persistent total corneal edema (7.3%), band keratopathy (7.3%), and significant inflammation (2.4%).	21283158
Inflammation	Altered Intercellular Communication	Elevation of serum c-reactive protein in patients with OAB and IC/BPS implies chronic inflammation in the urinary bladder.	21284020
Inflammation, Overactive Bladder	Altered Intercellular Communication	Chronic inflammation has been implicated in the development of overactive bladder (OAB) and interstitial cystitis/bladder pain syndrome (IC/BPS).	21284020
Inflammation	Altered Intercellular Communication	An elevation of C-reactive protein (CRP) has been associated with chronic inflammation and lower urinary tract symptoms.	21284020
Inflammation	Altered Intercellular Communication	Our data support the association between chronic inflammation of the urinary bladder in patients with OAB or IC/BPS.	21284020
Inflammation, Heart Injuries	Altered Intercellular Communication	To indicate the pathophysiologic background for cTnT release in Chagas heart injury, inflammation markers, such as C-reactive protein and interleukin 6, were measured in parallel.	21284445
Inflammation	Altered Intercellular Communication	The highly sensitive assay of cTnT release seems to be related to Chagas heart disease-specific inflammation.	21284445
Rheumatoid Arthritis, Inflammation, Autoimmune Disorder, CTCAE	Altered Intercellular Communication	Free radicals are involved in the pathogenesis of Rheumatoid arthritis, a systemic autoimmune disorder characterized by unchecked synovial inflammation.	21284489
Rheumatoid Arthritis	Altered Intercellular Communication	Taken together, this ex vivo study has established that allylpyrocatechol has potent scavenging activity and could be considered as an add-on therapy in the treatment of inflammation-associated disorders like Rheumatoid Arthritis.	21284489
Celiac Disease, Gastrointestinal inflammation, Intestinal Diseases	Altered Intercellular Communication	Increased concentration of nitric oxide (NO) metabolites, nitrite and nitrate, in the urine is a strong indication of ongoing small intestinal inflammation, which is a hallmark of the enteropathy of coeliac disease (CD).	21284717
Inflammation	Altered Intercellular Communication	The transient effect of SCIO-469 on acute-phase reactants suggests a complex role of p38 MAPK in inflammation.	21285160
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Chemical mediators of inflammation and resolution in post-operative abdominal aortic aneurysm patients.	21286796
Pneumonia, Ventilator-Associated, Inflammation, Critical Illness, Candida (fungus)	Altered Intercellular Communication	The relationship between Candida species cultured from the respiratory tract and systemic inflammation in critically ill patients with ventilator-associated pneumonia.	21287306
Inflammation, Candida (fungus)	Altered Intercellular Communication	only in the RT is associated with similar levels of inflammation and worse clinical outcomes compared with patients without Candida in RT secretions.	21287306
Inflammation, Viremia, Lymphopenia, Neutrophilia (finding)	Altered Intercellular Communication	When patients were segregated into high viral load and low viral load groups during the acute phase, those with high viremia had lymphopenia, lower levels of monocytes, neutrophilia, and signs of inflammation.	21288813
Inflammation, Muscular Atrophy, Fatty infiltration	Altered Intercellular Communication	Magnetic resonance (MR) parameters evaluated in 68 muscles of upper and lower extremity were muscle atrophy, fatty infiltration and inflammation.	21288962
Inflammation, Fatty infiltration	Altered Intercellular Communication	Fatty infiltration was far more common than inflammation.	21288962
Cerebrovascular Disorders, Inflammation, Hypertension, CTCAE, Iris hypoperfusion	Altered Intercellular Communication	Smaller retinal arteriolar calibers are strongly related to hypertension, whereas larger retinal venular calibers are more related to inflammation, cerebral hypoperfusion, and cerebrovascular disease.	21288987
Diabetes Mellitus, Insulin-Dependent, vascular inflammations, Diabetes Mellitus	Altered Intercellular Communication	Preadolescent children with type 1 diabetes and mean diabetes duration of 4 years displayed evidence of low-intensity vascular inflammation and attenuated FMD measurements.	21289230
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	These data suggest that endothelial dysfunction and systemic inflammation, known harbingers of future cardiovascular risk, are present even in preadolescent children.	21289230
Nephritis	Altered Intercellular Communication	ISN Forefronts Symposium 2010 in Sylt, Germany: 'Induction and Resolution of Renal Inflammation'.	21289596
Inflammation, Glomerulonephritis	Altered Intercellular Communication	The program included basic and clinical aspects of inflammation with a special focus on human and experimental glomerulonephritis.	21289596
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Distinguished scientists from different fields of inflammation research reported their recent discoveries and discussed emerging topics including the role of resolution for inflammatory processes; the 'new and old' cellular players of innate immunity and their mediators; the fundamental role of T-cell subtypes and chemokines; new aspects of B cell-mediated immune responses; and finally the potential implication of results from basic science for human inflammatory renal disease.	21289596
Inflammation	Altered Intercellular Communication	Signs of acute inflammation (redness, drainage, dehiscence) also were statistically equivalent.	21290007
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Inflammation, resulting in periductal fibrosis and compression of the duct orifices, may be a causative factor.	21290857
HD Term Type, Inflammation	Altered Intercellular Communication	IDO was negatively correlated with all markers of inflammation in HD patients.	21292009
Inflammation	Altered Intercellular Communication	It is possible that after its initial upregulation due to chronic inflammation, IDO curtails its own provoking agent, i.e., inflammation.	21292009
Inflammation, Thin-cap fibroatheroma	Altered Intercellular Communication	Fibroblast activation protein is induced by inflammation and degrades type I collagen in thin-cap fibroatheromata.	21292680
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	These ex vivo results are consistent with LTB(4) being the direct product of the reaction catalyzed by LTA4H and its role in promoting monocyte chemotaxis to sites of inflammation, including the artery wall of atherosclerotic lesions.	21293878
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	These data provide evidence linking inflammation to adverse outcomes beyond cardiovascular disease.	21293970
Inflammation, Impaired	Altered Intercellular Communication	Interventions targeting inflammation may prevent lung function impairment.	21293970
Inflammation, Dental Plaque, Dental caries	Altered Intercellular Communication	PT had more plaque and gingival inflammation and presented more BMP than C. No difference in caries prevalence was found.	21294392
Gastrointestinal Hemorrhage, Inflammation, Anemia, Traumatic injury	Altered Intercellular Communication	There are many causes of anemia in ICU patient such as gastrointestinal bleeding, anemia of chronic inflammation, trauma or surgery.	21294425
Inflammation, Prostate Cancer Outcomes Study, Dyslipidemias, Hyperandrogenism	Altered Intercellular Communication	PCOS was found to be associated with dyslipidemia, hyperandrogenism, IR and sub-clinical inflammation.	21294689
Intraocular inflammation, Uveitis	Altered Intercellular Communication	Retinal cells suppress intraocular inflammation (uveitis) through production of interleukin-27 and interleukin-10.	21294722
Intraocular inflammation, Uveitis	Altered Intercellular Communication	These results suggest that suppression of intraocular inflammation might be mediated through endogenous production of IL-27 and IL-10 by retinal cells, whereas SOCS proteins induced by IL-27 during uveitis may function to protect the neuroretinal cells from the toxic effects of pro-inflammatory cytokines.	21294722
Inflammation, Sarcoidosis, Lymphadenopathy	Altered Intercellular Communication	The lymphadenopathy specimens were biopsied via mediastinoscopy, and histological study revealed noncaseating epithelioid granulomatous inflammation consistent with sarcoidosis.	21295493
Inflammation, Heart failure	Altered Intercellular Communication	Several works have endorsed a significant role of the immune system and inflammation in the pathogenesis of heart failure.	21296316
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Inflammation is associated with the disruption of the aortic media and appears to play a fundamental role in the progression and development of abdominal aortic aneurysm (AAA).	21296538
Inflammation	Altered Intercellular Communication	Haptoglobin (Hp) is a genetically determined acute phase protein, the synthesis of which is increased during inflammation.	21296538
Inflammation, Thrombus of cardiac chamber	Altered Intercellular Communication	Previous studies on pathophysiology suggest a role for endothelial inflammation in atherothrombotic strokes and intracardiac thrombosis in cardioembolic strokes.	21296900
Inflammation, Experimental Autoimmune Encephalomyelitis	Altered Intercellular Communication	Together these findings demonstrate the presence of inflammation and neuronal stress in multiple sclerosis as well as in experimental autoimmune encephalomyelitis.	21297130
Inflammation, MS gene, Trauma, Nervous System	Altered Intercellular Communication	Since reduced noradrenaline levels could be permissive for increased inflammation and neuronal damage, these results suggest that methods to raise noradrenaline levels or increase locus coeruleus function may be of benefit in treating multiple sclerosis.	21297130
Granulomatous inflammation, Granulomatosis with polyangiitis, Systemic disease, Necrotizing vasculitis	Altered Intercellular Communication	Wegener's granulomatosis (WG) is a multisystemic disease of unknown etiology characterized by necrotizing vasculitis and granulomatous inflammation (1-3).	21297323
AIDS Dementia Complex, Inflammation, Trauma, Nervous System	Altered Intercellular Communication	Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment.	21297425
Inflammation, Prostate Cancer Outcomes Study, Leukocytosis	Altered Intercellular Communication	Systemic inflammation and reactive leukocytosis have also been described in PCOS.	21297528
Inflammation, Thrombocytosis	Altered Intercellular Communication	Therefore, from an etiological perspective, thrombocytosis appears to be at least partially independent from the classical pathways of systemic inflammation.	21297528
Inflammation, SMAD1 protein, human	Altered Intercellular Communication	Ab-Al seems critical in modulating key AD-related pathways such as glutamatergic transmission, Ca(2+) homeostasis, oxidative stress, inflammation, and neuronal apoptosis.	21298039
Chronic lymphocytic inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histological examination revealed large areas of fibrosis and focal lymphocytic inflammation mimicking infarction/myocarditis.	21298287
Diabetes Mellitus	Altered Intercellular Communication	Relationship between erythropoietin responsiveness, insulin resistance, and malnutrition-inflammation-atherosclerosis (MIA) syndrome in hemodialysis patients with diabetes.	21298620
Pulmonary Emphysema	Altered Intercellular Communication	Inflammation partly masks the presence of emphysema on CT and smoking cessation results in a paradoxical fall in lung density, which resembles rapid progression of emphysema.	21299472
Inflammation, Fibrosis Assessment, AURKAIP1 gene, Periphlebitis, Lymphoplasmacytic Infiltrate	Altered Intercellular Communication	AIP histology was defined by the presence of lymphoplasmacytic infiltration, periductal inflammation, fibrosis, and periphlebitis.	21299615
Inflammation, One Vessel Coronary Disease	Altered Intercellular Communication	Serum TRACP5a is a macrophage-derived inflammation marker associated with CVD risk, and with coronary vessel disease and its severity and may be a useful marker for screening and assessment of CVD risk.	21300043
Disability, Inflammation, Albuminuria, Diabetes Mellitus	Altered Intercellular Communication	To examine the relationship between albuminuria, inflammation, and disability in older adults with diabetes.	21300788
Inflammation, Albuminuria, Diabetes Mellitus	Altered Intercellular Communication	Albuminuria and inflammation were independent correlates for disability among older adults with diabetes.	21300788
Disability, Inflammation, Albuminuria, Diabetes Mellitus	Altered Intercellular Communication	There was an interaction of albuminuria and elevated CRP on disability, suggesting that the presence of subclinical inflammation may amplify the effect of albuminuria on disability in older adults living with diabetes.	21300788
Inflammation	Altered Intercellular Communication	Although his general condition improved, his systemic inflammation and chest radiograph findings did not.	21301164
biloma, Inflammation	Altered Intercellular Communication	PTBD treatment and additional CT-guided drainage of bilomas helped to reduce intraabdominal inflammation, as shown by reduction of inflammation parameters.	21301846
Gastrointestinal inflammation	Altered Intercellular Communication	IL-23 is, today, considered the key driver of intestinal inflammation and its role in inflammatory responses is tissue-specific.	21302302
Inflammatory abnormality of the eye, Traumatic injury, Corneal Diseases	Altered Intercellular Communication	Patients had no corneal disease, ocular inflammation, previous trauma or ocular surgery.	21302722
Inflammation, Neoplasms, Communicable Diseases, Stenosis Morphology, Traumatic injury, External auditory canal structure	Altered Intercellular Communication	Acquired external auditory canal (EAC) stenosis is described as resulting from a number of different causes such as infection, trauma, neoplasia, inflammation and radiotherapy.	21303316
Inflammation	Altered Intercellular Communication	These results demonstrate that Nrf2 regulates iron efflux from macrophages through Fpn1 gene transcription and suggest that Nrf2 may control iron metabolism during inflammation.	21303654
Inflammation	Altered Intercellular Communication	The activation of these pathways may contribute to the progression of inflammation, resulting in motor neuron injury.	21303685
Inflammation	Altered Intercellular Communication	Microscopic findings indicated that the transmural abscess contained massive inflammatory infiltrate and the cecal mucosa showed ulceration and inflammation with a fibrinous and purulent coating.	21304040
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Uptake of USPIO in abdominal aortic aneurysms identifies cellular inflammation and appears to distinguish those patients with more rapidly progressive abdominal aortic aneurysm expansion.	21304070
Refractory anemias, Rheumatoid Arthritis, destruction joint, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is characterized by inflammation and joint destruction, with the degree of damage varying greatly among patients.	21305530
Nephritis	Altered Intercellular Communication	EBV-DNA extraction supported the EBV involvement in renal tissue suggesting that both etiologic agents might have contributed to renal inflammation.	21305737
Inflammation	Altered Intercellular Communication	In conclusion, an unfavourable NOS substrate/inhibitor ratio may contribute to the reduced NO bioavailability associated with inflammation.	21306304
Pulmonary arterial hypertension, Inflammation, Congenital heart disease, Vasculitis, CTCAE, Pulmonary artery aneurysm	Altered Intercellular Communication	We report a rare case of idiopathic pulmonary artery aneurysm (PAA) in a 56-year-old woman without any causative conditions, such as congenital heart disease, inflammation, pulmonary artery hypertension, or systemic vasculitis.	21308440
Inflammation	Altered Intercellular Communication	The existence of monocyte subsets with distinct roles in homeostasis and inflammation suggests specialization of function.	21308491
vascular inflammations	Altered Intercellular Communication	Flow cytometric analysis of monocyte subsets and marker expression may provide valuable information on vascular inflammation.	21308491
Inflammation, Obesity	Altered Intercellular Communication	Furthermore, it is possible that obesity, which induces a chronic state of low-level inflammation in addition to several metabolic sequelae, may modify the impact of these SNPs.	21308720
Granulomatous inflammation, Hodgkin Disease	Altered Intercellular Communication	The cytologic diagnoses of the 31 adequate procedures included 19 with benign disease (8 reactive lymph nodes and 11 granulomatous inflammation), 8 with lymphoma (2 large B-cell, 2 small lymphocytic, 2 Hodgkin, 1 mantle cell, and 1 T-cell lymphoblastic), 2 with cells suspicious for Hodgkin lymphoma, and 2 cases with atypical cells.	21308997
Inflammation, Granuloma, Crohn Disease	Altered Intercellular Communication	Pathologic examination revealed inflammation in all layers of the appendiceal wall and noncaseating epithelioid cell granuloma, and a diagnosis of appendiceal Crohn's disease was made.	21309418
Inflammation	Altered Intercellular Communication	Differentially regulated genes were in the functional areas of inflammation and cell signaling.	21309737
Inflammation, Chronic hand eczema, Fissure	Altered Intercellular Communication	Case study 6--A 56-year-old male civil engineer with chronic hand eczema presenting as fissures and inflammation.	21309816
Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	FDG-PET/CT is widely used in the management of a variety of malignancies with excellent overall accuracy, despite the potential for false positive results related to infection and inflammation.	21309995
Inflammation	Altered Intercellular Communication	The correlation between CPCE and ICI suggests a role for CPCE as an independent marker of plaque inflammation.	21310564
Inflammation, Obesity	Altered Intercellular Communication	Association between obesity history and hand grip strength in older adults--exploring the roles of inflammation and insulin resistance as mediating factors.	21310808
Inflammation, Obesity	Altered Intercellular Communication	To examine the association between obesity history and hand grip strength, and whether the association is partly explained by subclinical inflammation and insulin resistance.	21310808
Inflammation	Altered Intercellular Communication	IL-1b receptor antagonist reduces inflammation in hemodialysis patients.	21310819
Inflammation	Altered Intercellular Communication	Chronic inflammation is highly prevalent in maintenance hemodialysis (MHD) patients and associates with increased mortality.	21310819
Airway structure, Asthma, Obesity	Altered Intercellular Communication	Airway inflammation is augmented by obesity and fatty acids in asthma.	21310876
Airway structure, Asthma	Altered Intercellular Communication	This was the first study to demonstrate an increase in neutrophilic airway inflammation in obese asthma.	21310876
Airway structure, Asthma	Altered Intercellular Communication	In males, saturated and monounsaturated fatty acids were important predictors of neutrophilic airway inflammation in asthma.	21310876
Inflammation, Crohn Disease	Altered Intercellular Communication	Polymorphisms of the RAGE gene have been described as a factor amplifying inflammation in susceptible patients, but the association with Crohn's disease (CD) is not known.	21311028
vascular inflammations	Altered Intercellular Communication	Pivotal role of protein kinase Cdelta in angiotensin II-induced endothelial cyclooxygenase-2 expression: a link to vascular inflammation.	21311042
vascular inflammations	Altered Intercellular Communication	The findings raise the possibility of curtailing endothelial COX-2 expression as a means of limiting or preventing vascular inflammation.	21311042
Osteomyelitis, Inflammation, bone destruction	Altered Intercellular Communication	Osteomyelitis was diagnosed with the help of and X-ray examination in 14,9%, multispiral computed tomography was informative in 48,4% and scintigraphy demonstrated bone destruction and inflammation in 96,8% of cases.	21311466
Granulation finding, Inflammation, Microcirculatory Bed	Altered Intercellular Communication	Morphologic analysis showed faster inflammation decrease and granulation as well as lesser microcirculatory disorders in wounds treated with photodynamic therapy.	21311467
Irritation - emotion, Inflammation	Altered Intercellular Communication	GU AEs and colposcopic findings consistent with mild epithelial irritation and inflammation occurred more commonly among women in the VivaGel arm.	21311578
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Blood transfusion during cardiac surgery is associated with inflammation and coagulation in the lung: a case control study.	21314930
Inflammation, Observation Method - Coagulation, Transfusion-Related Acute Lung Injury	Altered Intercellular Communication	We hypothesized that blood transfusion is associated with changes in pulmonary and systemic inflammation and coagulation occurring in patients who do not meet the clinical diagnosis of transfusion-related acute lung injury (TRALI).	21314930
Acute Lung Injury, Inflammation, Observation Method - Coagulation, Transfusion-Related Acute Lung Injury	Altered Intercellular Communication	Transfusion during cardiac surgery is associated with activation of inflammation and coagulation in the pulmonary compartment of patients who do not meet TRALI criteria, an effect that was partly dose-dependent, suggesting transfusion as a mediator of acute lung injury.	21314930
Sepsis, Inflammation, Disturbance	Altered Intercellular Communication	Hengyan medicinal recipe could not only reduce the systemic inflammation, but also plays a role in bidirectional regulation of the immune disturbance to ameliorate immune suppression of sepsis patients.	21315002
Inflammation, Disease of mucous membrane, Cardiovascular Diseases	Altered Intercellular Communication	Common oral mucosal diseases, systemic inflammation, and cardiovascular diseases in a large cross-sectional US survey.	21315218
Inflammation, Periodontitis, Atherosclerosis, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	Inflammation of the gingivae (periodontitis) has been associated with raised serum biomarkers of inflammation, sub-clinical markers of atherosclerosis, and increased risk of and/or mortality from cardiovascular disease (CVD).	21315218
Inflammation, Inflammatory disorder	Altered Intercellular Communication	There remain little information regarding the association between other common oral inflammatory disease, systemic inflammation, and CVD.	21315218
Inflammation, Disease of mucous membrane	Altered Intercellular Communication	Having oral mucosal disease was associated with systemic inflammation (serum levels of C-reactive protein >= 10 mg/dL) (odds ratio 1.41, 95% CI 1.02-1.94).	21315218
Oral mucous membrane structure, Inflammation	Altered Intercellular Communication	This is the first study to suggest that common oral mucosal diseases are independently associated with raised markers of systemic inflammation and history of CVD.	21315218
Inflammation, ETV3 wt Allele, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	In a population with prevalent MetS, low-grade inflammation is independently relevant for CHD, as are serum lipoproteins and smoking status.	21315565
Inflammation, Adult Hepatocellular Carcinoma	Altered Intercellular Communication	Green tea consumption, inflammation and the risk of primary hepatocellular carcinoma in a Chinese population.	21315679
FAM126A gene	Altered Intercellular Communication	Potential effect modifications of green tea on associations between primary HCC and alcohol drinking, HBV/HCV infection, and inflammation-related SNPs were suggested.	21315679
Inflammation, Acute heart failure	Altered Intercellular Communication	Inflammation and reduced endothelial function in the course of severe acute heart failure.	21316028
Inflammation, Shock, Cardiogenic	Altered Intercellular Communication	Systemic inflammation and elevated circulating levels of the endogenous nitric oxide inhibitor asymmetrical dimethylarginine (ADMA) have been associated with increased risk in cardiogenic shock (CS).	21316028
Inflammation, Organ Dysfunction Scores, Hypoperfusion	Altered Intercellular Communication	ADMA was related to organ dysfunction and degree of hypoperfusion during CS but showed no correlations to inflammation or hampered vasodilator function.	21316028
Inflammation, Chronic Kidney Diseases, Chronic malnutrition	Altered Intercellular Communication	The combination of chronic malnutrition and inflammation, often termed malnutrition-inflammation complex syndrome or protein-energy wasting, is common in patients with chronic kidney disease.	21316133
Cessation of life	Altered Intercellular Communication	We assessed the association of malnutrition-inflammation score (MIS) with all-cause mortality and death-censored transplant loss or death with a functioning transplant in a sample of kidney transplant recipients.	21316133
Inflammation, Malnutrition	Altered Intercellular Communication	Higher score reflects more severe degree of malnutrition and inflammation status.	21316133
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The downregulation of ACE2/angiotensin-(1-7)/-Mas receptor axis as well as AT(2)-receptors may promote fibrosis, proliferation and inflammation in patients with AS.	21316680
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Serum ferritin often increases with inflammation, and a higher cutoff may be better in those with acute and chronic inflammatory conditions, including those with chronic kidney disease (CKD).	21317036
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Serum ferritin often increases with inflammation, and a higher cutoff may be better in those with acute and chronic inflammatory conditions, including those with chronic kidney disease (CKD).	21317036
Pain Distress Question, Inflammation	Altered Intercellular Communication	The efficacy is observed for the main symptoms (pain) and on markers of inflammation (CRP), as well as disease severity in terms of spinal mobility and pulmonary function.	21317434
Inflammation	Altered Intercellular Communication	However, it is still unclear which environmental cues induce persistent activation of macrophages in vivo and how macrophage-derived effector molecules maintain chronic inflammation and affect resident fibroblasts essential for tissue homeostasis and repair.	21317534
Inflammation, Varicose Ulcer	Altered Intercellular Communication	We used a complementary approach studying human subjects with chronic venous leg ulcers, a model disease for macrophage-driven chronic inflammation, while establishing a mouse model closely reflecting its pathogenesis.	21317534
Inflammation	Altered Intercellular Communication	Via enhanced TNF-a and hydroxyl radical release, this macrophage population perpetuated inflammation and induced a p16(INK4a)-dependent senescence program in resident fibroblasts, eventually leading to impaired wound healing.	21317534
Inflammation, Colitis	Altered Intercellular Communication	We also observed reduced neutrophilic inflammation in an acute mouse model of colitis.	21317538
glycation, Primary malignant neoplasm, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	The receptor for advanced glycation end products (RAGE) plays a crucial role in several disease processes including diabetes, inflammation, and cancer.	21317562
Granulomatous, Acute inflammation, Pneumonia	Altered Intercellular Communication	Aspiration pneumonia most often presents in surgical lung biopsies as a granulomatous pneumonia with acute inflammation, microabscesses, and a granulomatous reaction to food or other particulate matter.	21317714
SLC26A5 gene, Inflammation, Hypertension, CTCAE, Kidney Diseases	Altered Intercellular Communication	This case report highlights that, in accordance with recent literature, PRES is a complication of a unique set of conditions comprising of inflammation, hypertension, immunosupression and nephropathy in different degrees and does not necessarily preclude the use of drugs implicated as inciting agents.	21318395
Vasculitis, Inflammation	Altered Intercellular Communication	After treatment, inflammation subsided, the exudative lesion shrank, and the frosted branch angiitis improved.	21319040
Inflammation, Fibrosis Assessment, Hepatitis B	Altered Intercellular Communication	Evaluation of adefovir & lamivudine in chronic hepatitis B: correlation with HBV viral kinetic, hepatic-necro inflammation & fibrosis.	21321419
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	In multivariate regression, histological inflammation was associated with an 85% decreased probability of cancer on repeat biopsy (odds ratio; OR 0.15; 95% confidence interval; CI 0.04-0.57; P=0.04).	21321586
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	In conclusion, inflammation was independently associated with a significantly decreased risk of cancer on repeat biopsy.	21321586
Orbital Pseudotumor	Altered Intercellular Communication	A multi-centre case series investigating the aetiology of hypertrophic pachymeningitis with orbital inflammation.	21322792
Orbital Pseudotumor	Altered Intercellular Communication	This was a retrospective case series of all patients presenting with hypertrophic pachymeningitis in association with orbital inflammation in 4 centres.	21322792
Pachymeningitis, Granulomatosis with polyangiitis, Orbital Pseudotumor	Altered Intercellular Communication	We postulate that the combination of orbital inflammation and pachymeningitis is strongly suggestive of Wegener granulomatosis, although it may take a number of years to confirm.	21322792
Inflammation	Altered Intercellular Communication	Permanent sections showed chronic inflammation and foreign body reaction.	21323272
Airway structure	Altered Intercellular Communication	Asthma manifests as TH2-dominant airway inflammation regulated by inducible T-cell kinase (ITK).	21323647
Inflammation	Altered Intercellular Communication	It is hypothesized that dysregulation of the autonomic nervous system (ANS) leads to increased inflammation via the cholinergic anti-inflammatory pathway.	21323913
Inflammation	Altered Intercellular Communication	This association supports the hypothesis that dysregulation of the ANS may lead to increased inflammation early in adulthood.	21323913
Inflammation, Psoriasis	Altered Intercellular Communication	Evaluation of soluble CD163 as a marker of inflammation in psoriasis.	21323937
Airway structure, Communicable Diseases, Chronic Obstructive Airway Disease, ARCN1 gene	Altered Intercellular Communication	Progressive airway inflammation and susceptibility to the airway colonisation and infection are characteristic for the pathophysiology of chronic obstructive pulmonary disease (COPD).	21324122
Communicable Diseases, Inflammation	Altered Intercellular Communication	High suPAR serum concentrations are suggested to reflect the activation of the immune system in circumstances of inflammation and infection, and have been associated with increased mortality in different populations of non-intensive care patients.	21324198
Inflammation, Metabolic Diseases, Myoglobinuria, Toxic effect, Communicable Diseases, Endocrine System Diseases, Traumatic injury	Altered Intercellular Communication	The differential diagnosis of myoglobinuria includes multiple etiologies, such as infection, inflammation, trauma, endocrinopathies, drugs toxicity, and primary metabolic disorders.	21324494
Inflammation, Sarcoidosis	Altered Intercellular Communication	Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis.	21324570
Inflammation, Sarcoidosis	Altered Intercellular Communication	Moreover, quercetin supplementation also reduced markers of oxidative stress and inflammation in the blood of sarcoidosis patients.	21324570
Inflammation, Sarcoidosis	Altered Intercellular Communication	Sarcoidosis patients might benefit from the use of antioxidants, such as quercetin, to reduce the occurring oxidative stress as well as inflammation.	21324570
Fibrosis Assessment, Fatty Liver Disease	Altered Intercellular Communication	In NASH lobular inflammation (OR, 3.77; 95%CI, 1.01-24.22) and RBP4 score (4.87; 1.003-23.65) were the only risk factors for fibrosis >=2 at logistic regression analysis.	21324757
Inflammation, Pain Distress Question	Altered Intercellular Communication	The involvement of the NOP-pN/OFQ system in inflammation, impaired immune function, and pain has to be further elucidated.	21324928
Chronic inflammation	Altered Intercellular Communication	Resistance to erythropoiesis-stimulating agents (ESAs) is often associated with chronic inflammation.	21325348
Inflammation, Anemia, Cardiovascular Diseases	Altered Intercellular Communication	Here, we investigated how anaemia, ESA resistance and the plasma levels of biological markers of inflammation could influence all-cause and cardiovascular disease morbidity and mortality.	21325348
HD Term Type, Inflammation	Altered Intercellular Communication	ESA responsiveness can be considered a strong prognostic factor in HD patients and seems to be tightly related to protein-energy wasting and inflammation.	21325348
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Selected dietary flavonoids are associated with markers of inflammation and endothelial dysfunction in U.S. women.	21325476
Inflammation, Metabolic Syndrome X, Cardiovascular Diseases, Atherosclerosis, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Dietary pattern may influence the risks of cardiovascular disease, atherosclerosis, type 2 diabetes, and metabolic syndrome through its effects on inflammation.	21325731
Liver carcinoma, Hypercalcemia, CTCAE	Altered Intercellular Communication	Severe hypercalcemia associated with hepatocellular carcinoma secreting intact parathyroid hormone: a case report.	21325766
Inflammation	Altered Intercellular Communication	Hypovitaminosis D is associated with systemic inflammation and concentric myocardial geometric pattern in hemodialysis patients with low iPTH levels.	21325871
HD Term Type, Hyperparathyroidism, Inflammation	Altered Intercellular Communication	The aim of this study was to identify hypovitaminosis D in HD patients without signs of hyperparathyroidism and to analyze its association to inflammation and echocardiographic alterations.	21325871
Inflammation	Altered Intercellular Communication	Hypovitaminosis D is associated with inflammation and concentric geometric pattern of the left ventricle, even in the absence of high iPTH levels.	21325871
Airway structure	Altered Intercellular Communication	In a model of airway inflammation healthy volunteers inhaled 20 mg of lipopolysaccharide (LPS), which resulted in an increase of small sputum macrophages from 18% +- 19% to 64% +- 25%.	21327296
Lymphoma	Altered Intercellular Communication	This suggests that the presence of chronic inflammatory conditions does not decisively influence the outcome of lymphoma patients.	21327940
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Type 2 diabetes is a manifestation of an ongoing low-grade inflammation.	21327984
Inflammation, Diabetes Mellitus, Impaired	Altered Intercellular Communication	In diabetes, impairment of neutrophil adhesion to the endothelium and migration to the site of inflammation were detected, which associated closely with adhesion molecules expressed on neutrophils and endothelial cells.	21327984
Inflammation, Familial Mediterranean Fever, Pulmonary Embolism	Altered Intercellular Communication	We identified untreated FMF and chronic inflammation as his only risk factor for pulmonary embolism.	21329287
Inflammation, Familial Mediterranean Fever	Altered Intercellular Communication	With this case report, we support recent studies that have demonstrated that inflammation may lead to prothrombotic states in patients with FMF.	21329287
Inflammation	Altered Intercellular Communication	Nuclear factor-kappa B (NF-kB) signalling plays an important role in gene regulation and is implicated in inflammation, oxidative stress and apoptosis.	21329555
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Besides regulating energy metabolism, leptin promotes and adiponectin suppresses inflammation which is a common feature of end-stage renal disease (ESRD).	21329629
Periodontal Diseases, atherosclerotic	Altered Intercellular Communication	These findings provide direct evidence for an association between periodontal disease and atherosclerotic inflammation.	21329844
Inflammation, Metabolic Diseases	Altered Intercellular Communication	Such association may be linked to the baseline mechanisms related to metabolic disorder (adiponectin) and systemic inflammation (hsCRP).	21330312
Inflammation, Hypertension, CTCAE, Cardiovascular Diseases	Altered Intercellular Communication	Elevated neutrophil count, a marker of systemic inflammation, has been suggested as a prognostic marker of cardiovascular disease in postmenopausal women with hypertension.	21331053
Inflammation, Obesity	Altered Intercellular Communication	Circulating oxidized LDL and inflammation in extreme pediatric obesity.	21331062
Inflammation, Obesity	Altered Intercellular Communication	Oxidative stress and inflammation have not been well-characterized in extreme pediatric obesity.	21331062
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	Extreme pediatric obesity, compared to milder forms of adiposity and NW, is associated with higher levels of oxidative stress and inflammation, suggesting that markers of early cardiovascular disease and type 2 diabetes mellitus are already present in this young population.	21331062
Inflammation, Nasal Polyps	Altered Intercellular Communication	Final histopathology of the remaining 23 patients was consistent with inflammation and/or nasal polyposis.	21331779
Inflammation, Anemia	Altered Intercellular Communication	However, their relation to nutrition, anemia, and micro inflammation is not well characterized.	21332333
Inflammation, Fibrosis Assessment, Diabetes Mellitus	Altered Intercellular Communication	In multivariate analysis, older age was associated with severe (Brunt >= 2) inflammation (odds ratio [OR] 1.1, P = 0.002) and severe (Brunt >= 3) fibrosis (OR 1.2, P = 0.001), diabetes was associated with severe inflammation (OR 3.18, P = 0.07) and severe fibrosis (OR 8.81, P = 0.002), and increased BMI was associated with severe fibrosis (OR 2.43, P = 0.07).	21332546
Inflammation, Fatty degeneration	Altered Intercellular Communication	Additionally, compared to Caucasians, Asian-Americans showed a trend toward an association with severe (Brunt > 2) steatosis (OR 3.83, P = 0.08) and severe inflammation (OR 5.42, P = 0.06).	21332546
Inflammation	Altered Intercellular Communication	The lesion was treated preoperatively with a potent topical corticosteroid resulting in a reduction of inflammation.	21332699
Inflammation, PLAU protein, human	Altered Intercellular Communication	Urokinase-type plasminogen activator receptor (uPAR) is expressed on a variety of different immune cells and vascular endothelial cells during inflammation.	21332843
Inflammation	Altered Intercellular Communication	Postoperative complications included 2 graft rejection episodes in 2 patients during the first year after surgery, 1 case of increased inflammation that required removal of the IOL, and 2 cases of new-onset glaucoma.	21333880
Glaucoma, CTCAE, Acute inflammation	Altered Intercellular Communication	Graft rejection, glaucoma, and postoperative inflammation are possible complications.	21333880
Inflammation, Chronic heart failure, Heart failure	Altered Intercellular Communication	In our previous study we have shown that inflammation was able to induce increased NT pro BNP in a hospital cohort with chronic heart failure in the elderly, indicating that NT-proBNP/BNP ratio should be evaluated concomitantly with inflammatory status to avoid overestimation of heart failure severity.	21334085
Inflammation, Erectile dysfunction	Altered Intercellular Communication	Previous data suggest a potential relationship between inflammation and erectile dysfunction.	21334642
Communicable Diseases, Inflammation	Altered Intercellular Communication	As organisms age the vulnerability to illnesses such as infection and inflammation increases and late complications due to infectious agents are mostly observed in the older part of the population.	21334752
Inflammation	Altered Intercellular Communication	Our results indicate a significant increase in Hsp70 serum levels with increasing degree of inflammation.	21334752
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	(r) being observed, surrogate markers of coagulation and inflammation seem to be less pronounced in patients where cardiotomy blood is not being directly reinfused.	21334912
Inflammation, Heart failure	Altered Intercellular Communication	The abundance of a preselection of transcripts involved in inflammation, immunosenescence and stress response was compared between PBMC of healthy aged donors and aged patients in acute phase of heart failure and at recovery.	21335025
Inflammation	Altered Intercellular Communication	Transcripts involved in inflammation and oxidative stress were more abundant.	21335025
Carcinoma of lung, Pneumonitis, Tuberculosis	Altered Intercellular Communication	Tuberculosis may increase lung cancer risk through substantial and prolonged pulmonary inflammation.	21335509
Inflammation, Carcinoma of lung, Lung	Altered Intercellular Communication	Our results add to the growing body of evidence implicating chronic inflammation and pulmonary scarring in the etiology of lung cancer.	21335509
methyldopa, Inflammation, Disease	Altered Intercellular Communication	Based on the obtained results, it may be concluded that lipid status disorder and inflammation could play an important role in the development of AMD in elderly people.	21336002
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Mediators of inflammation are the potential predicting factors of OA, however, with respect to examined chemokines development of a diagnostic test can be limited by the low serum concentration and lack of correlation with clinical and radiological signs of the disease.	21336628
Inflammation, Primary malignant neoplasm, Obesity	Altered Intercellular Communication	Obesity is characterized by chronic mild inflammation and may influence the risk and progression of cancer.	21336679
Sjogrens Syndrome", Inflammation, Sicca Syndrome	Altered Intercellular Communication	Whole stimulated salivary flow: correlation with the pathology of inflammation and damage in minor salivary gland biopsy specimens from patients with primary Sjogren's syndrome but not patients with sicca.	21337320
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Compared with unstimulated salivary flow, stimulated salivary flow appeared to be a better measure of inflammation (according to the focus score) and fibrosis.	21337320
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In the future, stimulated salivary flow may serve as a noninvasive surrogate biomarker of inflammation and fibrosis as well as a measure of response to treatment in patients with primary SS.	21337320
Acute inflammation	Altered Intercellular Communication	Computed tomographic enterography (CTE) has been shown to have a high sensitivity and specificity for active small bowel inflammation.	21337477
Enteritis	Altered Intercellular Communication	CTE is a clinically useful examination, altering management plans in nearly half of patients with CD, while increasing physician LOC for the detection of small bowel inflammation and penetrating disease.	21337477
Arthritis, Inflammatory polyarthritis	Altered Intercellular Communication	Reduction of long-term disability in inflammatory polyarthritis by early and persistent suppression of joint inflammation: results from the Norfolk Arthritis Register.	21337726
Inflammation	Altered Intercellular Communication	Remission was defined as the absence of clinically detectable joint inflammation on a 51-joint count.	21337726
Airway structure	Altered Intercellular Communication	Fraction of exhaled nitric oxide (FeNO) as a biomarker of airway inflammation in children warrants better clarification.	21338427
Ischemia, Inflammation, Brain Injuries, Neoplasms	Altered Intercellular Communication	Nestin expression has also been detected under such pathological conditions as ischemia, inflammation, and brain injury, as well as in various types of human solid tumors and their corresponding cell lines.	21340483
Anejaculation, Epilepsy	Altered Intercellular Communication	We report a case of ejaculation failure and abnormal hormonal profile in a patient affected by epilepsy.	21341560
Inflammation, Crypt	Altered Intercellular Communication	Resection margins revealed no significant difference in crypt distortion, depletion of mucin, acute inflammation, chronic inflammation and infiltration of eosinophils following NAT compared with controls.	21341624
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Cartilage oligomeric matrix protein - inflammation biomarker in knee osteoarthritis.	21342138
Inflammation, effusion, Idiopathic osteoarthritis, Synovitis	Altered Intercellular Communication	The aim of this study was to analyze and compare ultrasound parameters of joint inflammation, effusion and synovitis with the levels of COMP in the serum of patients with primary osteoarthritis.	21342138
Coughing, Chronic cough, Airway structure, Gastroesophageal reflux disease	Altered Intercellular Communication	Cough reflex sensitivity and airway inflammation in patients with chronic cough due to non-acid gastro-oesophageal reflux.	21342332
Neurogenic Inflammation, Coughing, Chronic cough, Gastroesophageal reflux disease, Hypersensitivity	Altered Intercellular Communication	Chronic cough due to non-acid reflux may be related to cough reflex hypersensitivity caused by neurogenic airway inflammation and mast cell activation, in which weakly acidic reflux is possibly a major factor.	21342332
Gastrointestinal inflammation	Altered Intercellular Communication	A new tachykinin, hemokinin (HK-1), has been identified in non-neuronal cells in recent years and its role in intestinal inflammation is unclear.	21342363
Inflammation	Altered Intercellular Communication	Inflammation lesions in kidney transplant biopsies: association with survival is due to the underlying diseases.	21342447
Inflammation, Tubulitis Assessment, Intimal Arteritis Assessment	Altered Intercellular Communication	We used a modified Banff classification, separately assessing inflammation (i-) in nonscarred (i-Banff), scarred (i-IFTA) and whole cortex (i-total), plus tubulitis and intimal arteritis.	21342447
Inflammation	Altered Intercellular Communication	In multivariate analysis, outcome was better predicted by the presence of progressive disease than by inflammation.	21342447
Inflammation	Altered Intercellular Communication	Thus inflammation in late kidney transplants has no inherent prognostic impact, but predicts reduced survival because inflammation indicates actively progressing diseases.	21342447
Inflammation, vinyltriethoxysilane	Altered Intercellular Communication	Blood markers of haemostasis and inflammation are not strongly predictive of VTE in older age however BMI, country and lower systolic blood pressure are independently associated with VTE risk.	21342490
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Herpes zoster disease	Altered Intercellular Communication	Background Systemic inflammation and dysregulated immune function in chronic obstructive pulmonary disease (COPD) is hypothesized to predispose patients to development of herpes zoster.	21343261
Hypogonadism, Failure, Klinefelter Syndrome	Altered Intercellular Communication	Twelve patients were eugonadic (normal LH, T, and FSH), while 18 displayed hormonal evidence of hypogonadism, characterized by tubular failure (increased FSH) in all the subjects and associated with interstitial failure in 14 subjects: seven with primary hypogonadism (increased LH and reduced T) and seven with compensated hypogonadism (increased LH and normal T).	21344196
allergic inflammation	Altered Intercellular Communication	Furthermore, local nasal IgE directed against these exotoxins may create a local allergic inflammation in the lateral wall of the nose.	21344448
Inflammation, Lemierre Syndrome, Thrombophlebitis, Phylum Fusobacteria	Altered Intercellular Communication	Here, we discuss a case of Lemierre syndrome in a 22-year-old man with thrombophlebitis of the facial vein and fusobacteria growth in the blood culture but no obvious focus of inflammation.	21345516
Inflammation	Altered Intercellular Communication	Furthermore, the dissociation of NfH(SMI35) levels with biomarkers of inflammation suggests that the mechanisms responsible for their production are at least partly independent.	21346223
Inflammation, Specimen Type - Fistula, Horseshoe	Altered Intercellular Communication	For all sequences, there was statistically significant agreement between readers for fistula classification, internal opening location, and the presence of sinus tracts, abscess, a horseshoe component, and inflammation.	21348010
Inflammation, Comorbidity	Altered Intercellular Communication	Comorbidity, inflammation status, race, age, and mesothelial cell mass are some factors correlated with the baseline dialysate-to-plasma ratio of creatinine.	21348373
Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	Bowel bacterial overgrowth as another cause of malnutrition, inflammation, and atherosclerosis syndrome in peritoneal dialysis patients.	21348395
Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	We explored the association between GL function, BBOS, and the malnutrition, inflammation, and atherosclerosis (MIA) syndrome.	21348395
Inflammation, Malnutrition, Communicable Diseases, Abnormal digestive tract function, Malabsorption Syndrome	Altered Intercellular Communication	The BBOS infectious process is found frequently in dialysis patients in association with GI malabsorption and maldigestion, malnutrition, and systemic inflammation.	21348395
Inflammation, Extracellular Matrix	Altered Intercellular Communication	In rare cases, skin metastases can manifest as lesions with signs of inflammation and are diagnosed as inflammatory cutaneous metastases (ICM).	21348413
Burn Specimen Source Codes, Inflammation	Altered Intercellular Communication	Microfluidics for T- lymphocyte cell separation and inflammation monitoring in burn patients.	21348958
Uveomeningoencephalitic Syndrome, Panuveitis, Choroiditis, Tuberculosis, Endophthalmitis, Orbital Pseudotumor	Altered Intercellular Communication	Multifocal choroiditis and panuveitis were the diagnosis in seven, ampiginous choroiditis in two, and for six remaining, serpiginous choroiditis, sympathetic ophthalmia, Vogt-Koyanagi-Harada syndrome, punctuate inner choroidopathy, tuberculosis and idiopathic inflammation.	21348964
Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation was strictly controlled in all cases by the time of injections.	21348964
Cataract, Inflammation, Uveomeningoencephalitic Syndrome	Altered Intercellular Communication	Recurrent inflammation is a critical poor prognostic factor for cataract surgery in VKH, but with appropriate management, good visual outcomes can be achieved.	21349937
Orbital Pseudotumor	Altered Intercellular Communication	Treatment of severe idiopathic orbital inflammation with intravenous methylprednisolone.	21349945
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Circulating follistatin in patients with chronic kidney disease: implications for muscle strength, bone mineral density, inflammation, and survival.	21350111
Inflammation, Cachexia	Altered Intercellular Communication	However, increased follistatin levels occurred together with increased inflammation, reduced muscle strength, and low BMD, suggesting an involvement of a mechanism including follistatin in the uremic wasting process.	21350111
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Sex differences in age trajectories of physiological dysregulation: inflammation, metabolic syndrome, and allostatic load.	21350248
Inflammation, Spinal Fractures	Altered Intercellular Communication	Optimal control of inflammation may be an effective means to protect against vertebral fractures.	21350894
Degenerative polyarthritis, Damage	Altered Intercellular Communication	Matrix metalloproteinases (MMP)-13, the major type II collagen-degrading collagenase, is regulated by stress-, inflammation-, and differentiation-induced signals that not only contribute to irreversible joint damage (progression) in OA, but importantly, also to the initiation/onset phase, wherein chondrocytes in articular cartilage leave their natural growth- and differentiation-arrested state.	21351054
Inflammation, Colorectal Carcinoma, Neoplasms	Altered Intercellular Communication	Chronic inflammation is an established risk factor for colorectal cancer (CRC), and polymorphisms in genes regulating inflammatory processes appear to alter the risk for neoplasia and the efficacy of nonsteroidal anti-inflammatory drugs in CRC chemoprevention.	21351261
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	We examined the association between selected inflammation gene polymorphisms and CRC risk.	21351261
Inflammation, Squamous cell carcinoma, Neoplasms	Altered Intercellular Communication	Tumour infiltrating CD25+ FoxP3+ regulatory T cells (Tregs) relate to tumour grade and stromal inflammation in oral squamous cell carcinoma.	21352381
Cessation of life, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Abdominal aortic aneurysm is associated with inflammation and is a common cause of illness and death among European populations.	21352499
Inflammation	Altered Intercellular Communication	The soluble urokinase plasminogen activator receptor (suPAR) is a plasma marker of low grade inflammation and has been associated with cardiovascular risk.	21354571
Inflammation, Osteochondritis Dissecans	Altered Intercellular Communication	However, increasing evidence suggests that central and systemic inflammation triggered by surgery likely plays a fundamental role in POCD developing and progression.	21354710
Inflammation, Osteochondritis Dissecans, Impaired cognition	Altered Intercellular Communication	Considering that inflammation may be a potential factor of POCD and minocycline is effective in improving cognitive dysfunction induced by inflammation, we hypothesize that minocycline may be useful to treat/prevent the POCD development after surgery in elderly patients.	21354710
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Our study suggests that inflammation associated with OSAS might contribute to atrial structural and electrical remodeling in OSAS patients with PAC.	21354892
Gingivitis	Altered Intercellular Communication	Sixty-four consecutive volunteers presenting with gingival inflammation were recruited at their semi-annual recall appointments for this study.	21356022
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Brain inflammation is induced by co-morbidities and risk factors for stroke.	21356305
Inflammation, Atherosclerosis, Diabetes Mellitus, Cerebrovascular accident, Obesity	Altered Intercellular Communication	Chronic systemic inflammatory conditions, such as atherosclerosis, diabetes and obesity are associated with increased risk of stroke, which suggests that systemic inflammation may contribute to the development of stroke in humans.	21356305
Inflammation	Altered Intercellular Communication	First, we assessed inflammatory changes in the brain in rodent models of chronic, systemic inflammation.	21356305
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	These findings show that brain inflammation occurs in animals, and tentatively in humans, harbouring risk factors for stroke associated with elevated systemic inflammation.	21356305
Inflammation, Atherosclerosis, Diabetes Mellitus, Cerebrovascular accident, Obesity	Altered Intercellular Communication	Chronic systemic inflammatory conditions, such as atherosclerosis, diabetes and obesity are associated with increased risk of stroke, which suggests that systemic inflammation may contribute to the development of stroke in humans.	21356305
Liver damage, Hepatic inflammation, Cholestasis, Intrahepatic bile duct	Altered Intercellular Communication	The results suggest that in this model of chronic cholestasis, fibrin constrains the release of bile constituents from injured intrahepatic bile ducts, thereby limiting the progression of hepatic inflammation and hepatocellular injury.	21356363
Inflammation	Altered Intercellular Communication	The relationship between AGEs, RAGE, and inflammation has not been well characterized.	21357189
Inflammation	Altered Intercellular Communication	These findings suggest that plasma esRAGE plays a role in modulating inflammation, although the exact mechanisms remain to be elucidated.	21357189
Inflammation, Pruritus	Altered Intercellular Communication	A 28-year-old man, presented with edematous and erythematous patchy lesion along with pruritus and inflammation on lip, have been suffering since 3 hours.	21357631
Nasal inflammation	Altered Intercellular Communication	Serial measurements of surrogates of nasal inflammation (such as nitric oxide or cytokine levels) were not performed.	21357906
Vasculitis	Altered Intercellular Communication	Fas and Fas Ligand have been implicated in apoptosis and vessel wall inflammation.	21359408
Plexiform ameloblastoma, Acute inflammation	Altered Intercellular Communication	In reopening the previous marsupialization, a new biopsy was performed with histopathologic findings compatible with plexiform ameloblastoma associated with acute inflammation.	21360116
Depression, CTCAE	Altered Intercellular Communication	Association between depression and malnutrition-inflammation complex syndrome in patients with continuous ambulatory peritoneal dialysis.	21360161
Depression, CTCAE	Altered Intercellular Communication	The prevalence of depression and its relation with the malnutrition-inflammation complex syndrome (MICS) have not yet been clearly defined in Chinese continuous ambulatory peritoneal dialysis (CAPD) patients.	21360161
Depression, CTCAE	Altered Intercellular Communication	The Hamilton Depression Scale (HAMD) and the malnutrition-inflammation score (MIS) were used for depression and MICS evaluation, respectively.	21360161
Depression, CTCAE	Altered Intercellular Communication	Clinical, socioeconomic, and malnutrition-inflammation factors were compared among patients with and without depression.	21360161
hearing impairment, Inflammation, NLRP3 gene	Altered Intercellular Communication	Organ manifestations of MWS improved, as did all patient-derived measures of health status, markers of inflammation, and hearing loss in 2 of the patients.	21360513
Rupture, Granulomatous inflammation	Altered Intercellular Communication	Parietal rupture was present, accompanied by granulomatous inflammation.	21361125
Inflammation, Ankylosis	Altered Intercellular Communication	No signs of inflammation, root resorption, ankylosis, mobility, sensitivity, pocket problems, or pulp destructions were found after 2-year follow up.	21361776
Inflammation	Altered Intercellular Communication	Inflammation with focal and/or diffuse concentration of round cells was detected in the SN in 22 cases (44%).	21361943
Inflammation, Early-onset, diabetic	Altered Intercellular Communication	The homozygous CC genotype of rs1333049 confers a magnified risk of early-onset and more severe CAD in diabetic patients through a novel biological pathway unrelated to glucose metabolism or inflammation.	21362310
Degenerative polyarthritis, Inflammation, LPCAT3 gene	Altered Intercellular Communication	The authors detected four unexpected biomarkers (V65 vitronectin fragment, C3f peptide, CTAP-III and m/z 3762 protein) that could be relevant in the pathophysiological process of OA as having significant correlation with parameters reflecting local inflammation and bone remodelling, as well as decrease in cartilage turnover.	21362709
Inflammation, Rheumatoid Arthritis, Erosion of bone	Altered Intercellular Communication	Circulating Dickkopf-1 is correlated with bone erosion and inflammation in rheumatoid arthritis.	21362762
Refractory anemias, Inflammation, Erosion of bone	Altered Intercellular Communication	DKK-1, as an important mediator, was correlated with bone erosion and inflammation in RA.	21362762
Ulcerative Colitis-Associated Colorectal Adenocarcinoma, Inflammation	Altered Intercellular Communication	Ulcerative colitis-associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation.	21363920
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation plays a role in the progression to cancer and it is linked to the presence of senescent cells.	21363920
Inflammation, Neoplasms, Ulcerative Colitis	Altered Intercellular Communication	We hypothesized that a preneoplastic field of inflammation, telomere shortening, and senescence underlies tumor progression in UC progressors.	21363920
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Multiple biopsies of varying histologic grade were collected along the colon of nine UC progressors and analyzed for telomere length, DNA damage, senescence, p53, p16, and chronic and acute inflammation.	21363920
Inflammation, Dysplasia	Altered Intercellular Communication	These results suggest that dysplasia arises in a preneoplastic field of chronic inflammation, which leads to telomere shortening, DNA damage, and senescence.	21363920
Inflammation	Altered Intercellular Communication	Elevated inflammation has been associated with a number of poor health outcomes.	21364200
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Participation in moderate-intensity physical activity may buffer the risk of higher inflammation often associated with higher levels of depressive symptoms.	21364200
Centrilobular Opacity	Altered Intercellular Communication	Extra-fine particle inhaled corticosteroids could be an alternative approach in centrilobular opacities caused by eosinophilic peripheral airway inflammation.	21364311
Neoplasms	Altered Intercellular Communication	Because of its proximity to the teeth and periodontium, the tumor can mimic tooth-related benign inflammatory conditions.	21365032
Inflammation	Altered Intercellular Communication	This allows a substantially increased bacterial uptake, which may contribute to recurrence of inflammation.	21366635
Infection, atherosclerotic, Cardiovascular Diseases	Altered Intercellular Communication	Our results suggest revisiting the hypothesis that infections may have a causative role in atherosclerotic inflammation and have implications for research regarding novel diagnostics and treatments for cardiovascular disease.	21366733
Coma (genus), Inflammation, Cerebral dysfunction, Sepsis, Delirium	Altered Intercellular Communication	In our pilot study, high baseline inflammatory biomarkers predicted prolonged periods of acute brain dysfunction, implicating inflammation as an important mechanism in the pathophysiology of delirium and coma during critical illness, irrespective of whether patients had sepsis or not.	21366899
Inflammation, Edema of lower extremity, Venous Insufficiency	Altered Intercellular Communication	No pharmacological treatment exists for lower extremity pitting edema, characterized by inflammation, found in chronic venous insufficiency.	21366964
Inflammation, Hypertriglyceridemia, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome components, such as increased waist circumference, hypertriglyceridaemia and smoking, were inversely associated with RHI as were serum markers of inflammation.	21367423
Papilledema, Retinitis, Edema, Uveitis, Vitritis, Conjunctivitis, Keratoconjunctivitis	Altered Intercellular Communication	With their ability to migrate into the cornea and release toxins, caterpillar hairs can induce different clinical presentations such as conjunctivitis, keratoconjunctivitis, uveitis, and less frequently vitreoretinal inflammation (hyalitis, papillitis, macular edema).	21367484
ARCN1 gene, Inflammation, Comorbidity, Data Type -Character	Altered Intercellular Communication	COPD is characterized by a multi-component character involving a state of low-grade systemic inflammation and an increased prevalence of cardiovascular co-morbidity.	21367591
ARCN1 gene, Inflammation	Altered Intercellular Communication	The role of circulating leptin and other adipokines in the involvement of the systemic inflammation in COPD is only studied scarcely.	21367591
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The results support the hypothesis that chronic inflammation plays a role in cancer.	21368452
Autoimmune Diseases, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Recently, a subset of IL-17 producing T cells distinct from Th1 or Th2 cells has been described as key players in inflammation and autoimmune diseases as well as cancer development.	21369705
Allergic, Inflammation	Altered Intercellular Communication	Leukotrienes, especially LTC4, are important inflammatory mediators in allergic and nonallergic inflammation of the entire airways.	21370724
Nasal Polyps, Asthma, Eosinophilic inflammation	Altered Intercellular Communication	Leukotriene 1 receptor blockade led to a significant decrease in eosinophil inflammation accompanied by a reduction in other mediators such as neurokinin A and substance P in the nasal lavage fluid of patients with nasal polyps and asthma, with or without aspirin intolerance.	21370724
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	The prevalence of CRSwNP with pronounced eosinophilic inflammation is steadily increasing and is classified as eosinophilic chronic rhinosinusitis (ECRS) in Japan.	21371840
PDR gene, Acute inflammation	Altered Intercellular Communication	This was associated with a significantly higher postoperative inflammation and IOP in PDR group.	21372484
Acute inflammation, diabetic	Altered Intercellular Communication	The higher postoperative inflammation and IOP following vitrectomy in diabetic eyes, especially when combined with endolaser photocoagulation, makes such eyes less susceptible to wound sealing-related complications following sutureless vitrectomy.	21372484
Cell Death, vascular inflammations, Diabetic Retinopathy	Altered Intercellular Communication	Cannabinoid 1 receptor activation contributes to vascular inflammation and cell death in a mouse model of diabetic retinopathy and a human retinal cell line.	21373835
Inflammation, Cardiomyopathies, Atherosclerosis, Cardiac dysfunction, Kidney Diseases, Cessation of life	Altered Intercellular Communication	Recent studies have demonstrated that cannabinoid-1 (CB(1)) receptor blockade ameliorated inflammation, endothelial and/or cardiac dysfunction, and cell death in models of nephropathy, atherosclerosis and cardiomyopathy.	21373835
Diabetic Retinopathy	Altered Intercellular Communication	Activation of CB(1) receptors may play an important role in the pathogenesis of diabetic retinopathy by facilitating MAPK activation, oxidative stress and inflammatory signalling.	21373835
Fibrosis Assessment	Altered Intercellular Communication	Green tea polyphenols avert chronic inflammation-induced myocardial fibrosis of female rats.	21373880
Fibrosis Assessment	Altered Intercellular Communication	Green tea proposes anti-inflammatory properties which may attenuate chronic inflammation-induced fibrosis of vessels.	21373880
Fibrosis Assessment, Chronic inflammation	Altered Intercellular Communication	This study evaluated whether green tea polyphenols (GTP) can avert fibrosis or vascular disruption along with mechanisms in rats with chronic inflammation.	21373880
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	GTP attenuates myocardial fibrosis through a suppression of chronic inflammation and innate immune responses.	21373880
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	NSCLC arises in the complex environment of chronic inflammation.	21373990
Amblyopia, Intraocular inflammation, Disease remission, Unspecified visual loss	Altered Intercellular Communication	Of eyes with active disease, the main contributors to vision loss at presentation were intraocular inflammation (74.8%) and macular involvement (24.3%), whereas in eyes with inactive lesions the main contributors to vision loss were macular scar formation (67.9%) and amblyopia (11.3%).	21374556
Amblyopia, Inflammation	Altered Intercellular Communication	The most common contributors to decreased vision in eyes with active lesions were inflammation and macular involvement, whereas in eyes with inactive lesions they were macular scar formation and amblyopia.	21374556
Inflammation	Altered Intercellular Communication	Regulation of VEGF expression in human retinal cells by cytokines: implications for the role of inflammation in age-related macular degeneration.	21374591
methyldopa, Inflammation, Age related macular degeneration	Altered Intercellular Communication	Chronic inflammation is implicated in the pathogenesis of age-related macular degeneration (AMD).	21374591
Inflammation, Atopy	Altered Intercellular Communication	Imbalance of Th17/Treg has been considered critical in the development of inflammation and atopic reactions.	21375554
Tuberculosis, Acute and chronic inflammation, Septicemia, Takayasu Arteritis	Altered Intercellular Communication	Chronic infective and inflammatory conditions included tuberculosis (n = 4), HIV (n = 3), staphylococcal septicemia (n = 2), and Takayasu arteritis (n = 1).	21376188
Inflammation, Rhinosinusitis, Nasal Polyps	Altered Intercellular Communication	Our result demonstrated strong evidence that diffuse mucosal inflammation and active cellular proliferation do exist in rhinosinusitis with nasal polyposis.	21377232
Airway structure	Altered Intercellular Communication	There was no relationship between EBC pH and disease severity, as assessed by the percent predicted FEV(1), nor with airway inflammation as assessed by sputum leukocyte counts.	21377342
ARCN1 gene, Airway structure	Altered Intercellular Communication	EBC pH is lower in COPD than in healthy control non-smokers, but does not differentiate COPD from smokers without COPD, relate to disease severity or to airway inflammation, and does not respond to corticosteroids.	21377342
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	TLR4 and RAGE: similar routes leading to inflammation in type 2 diabetic patients.	21377387
Inflammation, Aortic Aneurysm, Aneurysm, Ruptured, Atherosclerosis	Altered Intercellular Communication	Tight, diffuse pleural adhesion and the vulnerable wall of an aortic aneurysm due to advanced atherosclerosis with active inflammation appeared to have predominantly contributed to the penetration of the ruptured aneurysm into the lung.	21377396
Inflammation, Renal function	Altered Intercellular Communication	Vascular health, systemic inflammation and progressive reduction in kidney function; clinical determinants and impact on cardiovascular outcomes.	21378154
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Systemic inflammation, endothelial dysfunction and arterial thickening contribute to the elevated cardiovascular risk of dialysis patients.	21378154
Inflammation, Endothelial dysfunction, Thickened	Altered Intercellular Communication	Endothelial dysfunction, arterial thickening and inflammation occur in parallel with the decline in eGFR, contributing to the increased cardiovascular risk of nondialysed CKD.	21378154
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Thiazolidinediones such as rosiglitazone (RSG) are insulin-sensitizing agents, which may improve inflammation and vascular function, and thus potentially lower cardiovascular risk in patients with chronic kidney disease (CKD).	21378155
Cytomegalovirus Infections, Inflammation	Altered Intercellular Communication	Future work should target the mechanisms by which CMV infection and low-level inflammation interact to yield significant impact on mortality.	21379581
MPP1 wt Allele	Altered Intercellular Communication	This selective pressure becomes more relaxed in the adult organism, permitting the onset of aging-associated diseases and inflammation-related aging; this concept echoes the antagonistic pleiotropy hypothesis of aging.	21380541
Inflammation, Ulcer	Altered Intercellular Communication	Biopsies from the ulcers showed only non-specific inflammation.	21380762
Inflammation	Altered Intercellular Communication	Endogenous opioid peptides have been shown to play a role in the development and/or perpetuation of inflammation.	21380937
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	We hypothesize that the endogenous opioid system is involved in inflammatory bowel disease, and antagonism of the opioid-opioid receptor will lead to reversal of inflammation.	21380937
Inflammation, Carcinogenesis	Altered Intercellular Communication	These findings support the importance of localized inflammation in alimentary tract carcinogenesis.	21381009
Inflammation, Obesity, Visceral	Altered Intercellular Communication	Visceral obesity and inflammation markers in relation to serum prostate volume biomarkers among apparently healthy men.	21382022
Inflammation, Dental Plaque, Osteopenia	Altered Intercellular Communication	Forty-two implants were assessed for implant survival, marginal bone loss, surgical and/or prosthetic complications, presence or absence of plaque, signs of inflammation and size of the papilla.	21382092
Inflammation, Dental Plaque	Altered Intercellular Communication	Repeated soft-tissue examinations revealed healthy conditions in terms of 6.1% plaque and 4.2% of the implants with signs of inflammation at the 5-year control.	21382092
Inflammation	Altered Intercellular Communication	Angiotensin converting enzyme (ACE) is a regulator of renin angiotensin system (RAS) that plays an important role in the physiology of the vasculature, blood pressure, inflammation, adipocyte distribution of various diseases.	21382792
Inflammation	Altered Intercellular Communication	Electron microscopy demonstrated that inflammation was caused by Cryptococcus neoformans, which was localized exclusively within macrophages, where it grew with budding.	21384279
Inflammation, Hepatitis C	Altered Intercellular Communication	Relationship between the interleukin-28b gene polymorphism and the histological severity of hepatitis C virus-induced graft inflammation and the response to antiviral therapy after liver transplantation.	21384511
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Genetic variants of cytokines involved in the immune response may contribute to the degree of graft inflammation, fibrosis progression, and antiviral therapy outcome.	21384511
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	605 protocol liver biopsies performed 0.5 to 10 and more than 10 years after transplantation were evaluated according to Desmet and Scheuer classification of inflammation and fibrosis.	21384511
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Polymorphisms in genes controlling inflammation and tissue repair in rheumatoid arthritis: a case control study.	21385363
Sarcoidosis, Aspergillosis, Orbital Pseudotumor	Altered Intercellular Communication	Thirty-three patients were analysed, consisting of 15 patients with orbital WG, 11 with idiopathic orbital inflammation, 6 with orbital sarcoidosis and one with aspergillosis.	21385547
Granulomatous inflammation, orbit (eye disorders), Vasculitis, CTCAE	Altered Intercellular Communication	Diagnostic findings indicating orbital WG were ear/nose/throat involvement, multiple organ system involvement, a positive ANCA, and on histology vasculitis, whereas granulomatous inflammation without signs of vasculitis was more indicative of another orbital disease.	21385547
Orbital Melanoma	Altered Intercellular Communication	Four months after surgery, follow-up positron emission tomography/CT imaging revealed physiologic metabolic activity in the MEDPOR implant with no evidence of orbital melanoma or chronic inflammation.	21386739
Inflammation, Obesity, Metabolic Stress	Altered Intercellular Communication	In obesity, metabolic stress and inflammation in injured tissues could favour enhanced shedding of procoagulant microparticles (MPs).	21386797
Inflammation, Hyperplastic Polyp, Endothelium	Altered Intercellular Communication	In obese females, we sought to evaluate the impact of a very low-calorie diet (VLCD) on procoagulant MP levels, fibrinolytic status, inflammation and endothelium damage.	21386797
Inflammation, Blood Vessel	Altered Intercellular Communication	Circulating biomarkers of vascular damage, fibrinolytic status, platelet activation and inflammation were measured before, 30 and 90 days after starting a short-term VLCD.	21386797
Inflammation	Altered Intercellular Communication	Secretion is linked to the size and number of adipocytes, as well as to concomitant secretion of inflammatory mediators, suggesting that TRAP is involved in fat accumulation and adipose inflammation.	21386798
Lymphocytic hypopituitarism, Neuroendocrine disease or syndrome, Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Lymphocytic hypophysitis (LYH) is a rare neuroendocrine disorder characterized by autoimmune inflammation of the pituitary gland.	21387696
Orchitis	Altered Intercellular Communication	Pathologically bony cartilage change was seen but no definite auricular inflammation findings.	21387702
Cartilage destruction, Inflammation, polychondritis, Traumatic injury	Altered Intercellular Communication	Residual auricular cartilage scarring, however, indicated cartilage destruction by previous inflammation or trauma, yielding a final diagnosis of relapsing polychondritis.	21387702
Inflammation	Altered Intercellular Communication	Perturbed expression and function of immune regulatory molecules called leukocyte immunoglobulin-like receptors (LILRs) may contribute to uncontrolled inflammation.	21388353
Inflammation	Altered Intercellular Communication	The pure medical-grade silicon implanted in miniscule amounts in a controlled manner results in minimal fibroplasia without significant inflammation.	21388657
Inflammation, Musculoskeletal Pain	Altered Intercellular Communication	Polymyalgia rheumatica (PMR) is characterized by aching proximal muscles and systemic inflammation.	21388741
Airway structure	Altered Intercellular Communication	Exhaled breath condensate (EBC) analysis is a non-invasive method to repeatedly evaluate airway inflammation.	21389585
Inflammation, Proteostasis Deficiencies, Toxic effect	Altered Intercellular Communication	Cell damage during the course of inflammation results in cytoplasmic actin release, which if not eliminated by the extracellular actin scavenger system, composed of gelsolin and vitamin D binding protein, can cause dysfunction of hemostasis and toxicity towards surrounding cells.	21389683
Inflammation, Thrombosis, Pulmonary Hypertension	Altered Intercellular Communication	Independent predictors of elevated D-dimer in CVD patients with no visible thromboses are as follows: female gender, age >68 years, acute inflammation, pulmonary hypertension, and decompensation of CCI.	21389943
Inflammation	Altered Intercellular Communication	New-generation leads present a sophisticated design with improved geometry and steroid-eluting tips to reduce chronic inflammation, maintaining a low pacing threshold and high sensing capability.	21391322
Retinal Detachment, Retinitis, Neurocysticercosis	Altered Intercellular Communication	The natural history of ocular neurocysticercosis or enhanced sub-retinal inflammation due to Albendazole therapy could have resulted in the retinal detachment in this case.	21391379
Celiac Disease, Inflammation	Altered Intercellular Communication	Coeliac disease is a chronic inflammation of the intestinal mucosa controlled by gluten-specific T cells restricted by disease-associated HLA-DQ molecules.	21392045
Colitis, Ischemic, Colitis	Altered Intercellular Communication	A computed tomography (CT) scan of the abdomen was conducted, which revealed left colonic inflammation consistent with colonic ischemia.	21392850
Inflammation, Progranulins, GRN wt Allele	Altered Intercellular Communication	The growth factor progranulin (PGRN) has been implicated in embryonic development, tissue repair, tumorigenesis, and inflammation, but its receptors remain unidentified.	21393509
Inflammation, Arthritis, GRN wt Allele	Altered Intercellular Communication	PGRN and Atsttrin prevented inflammation in multiple arthritis mouse models and inhibited TNFa-activated intracellular signaling.	21393509
Inflammation, Dental Plaque	Altered Intercellular Communication	Carotid plaque and candidate genes related to inflammation and endothelial function in Hispanics from northern Manhattan.	21393601
Inflammation, Salpingitis	Altered Intercellular Communication	Xanthogranulomatous salpingitis (XGS) is a rare form of chronic inflammation of the fallopian tubes.	21393899
Chronic salpingitis, Xanthogranulomatous inflammation, Adnexal Mass	Altered Intercellular Communication	Chronic active follicular salpingitis with xanthogranulomatous inflammation might give the impression of a cystic adnexal mass with septations on preoperative pelvic computed tomography.	21393899
Inflammation	Altered Intercellular Communication	Eye pathologic examination at autopsy showed ischemic changes, but no inflammation.	21394060
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Ang II Upregulation of the T-lymphocyte renin-angiotensin system is amplified by low-grade inflammation in human hypertension.	21394089
Inflammation, Damage, Terminal Osseous Dysplasia and Pigmentary Defects, Hypertension, CTCAE	Altered Intercellular Communication	Low-grade inflammation facilitates the development of essential hypertension and target organ damage (TOD).	21394089
Inflammation, Terminal Osseous Dysplasia and Pigmentary Defects, Hypertension, CTCAE	Altered Intercellular Communication	In hypertension, an Ang II-driven activation of T-cell RAS, further amplified by low-grade inflammation, does occur and is associated to worse TOD.	21394089
Inflammation, Obesity	Altered Intercellular Communication	Morbid obesity is associated with a state of chronic inflammation.	21394384
Coughing, Bronchitis	Altered Intercellular Communication	From this observation we suggest that FeNO measurement should be added to the investigation of work-related cough during specific inhalation challenge, and may be considered as an alternative to induced sputum to evaluate bronchial inflammation when sputum collection is unavailable or unsuccessful.	21394743
Inflammation	Altered Intercellular Communication	These results allow us to suggest that the majority of patients with anterior eye inflammation have inflammatory changes in posterior segment.	21394992
Structure of palpebral fissure, Exophthalmos, Lagophthalmos, Orbital Pseudotumor	Altered Intercellular Communication	The following factors were found to be associated with corneal involvement in TED patients: activity of orbital inflammation, proptosis, lagophthalmos, palpebral fissure height, lower lid retraction, grade of conjunctival vital staining and low corneal sensitivity.	21394999
IL13 gene	Altered Intercellular Communication	These preliminary data show a decrease in nasal tactile sensitivity and point out interesting aspects of the nasal chronic inflammatory condition in allergic rhinitis.	21395473
Inflammation, Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	Pulmonary mucosa-associated lymphoid tissue lymphoma is unique in that chronic inflammation is rare and that API2-MALT1 fusion, resulting from t(11;18)(q21;q21), occurs frequently.	21396678
Polyp of ethmoidal sinus, Inferior nasal concha	Altered Intercellular Communication	The degree of inferior turbinate inflammation correlated with that of the ipsilateral polyp of ethmoid sinus in both groups.	21396869
Nasal Polyps, Inferior nasal concha, Sinusitis, Asthma, Chronic sinusitis	Altered Intercellular Communication	The ethmoid sinus inflammation in polypoid chronic sinusitis is accompanied by a proportionate inferior turbinate inflammation, not only in the patients with asthma but also in those with isolated sinonasal polyposis.	21396869
methyldopa, Inflammation, Subretinal deposits, Family history	Altered Intercellular Communication	Given the high pathophysiological levels of bioavailable zinc present in subretinal deposits, we discuss how zinc binding to FH may contribute to deposit formation and inflammation associated with AMD.	21396937
Pain Distress Question	Altered Intercellular Communication	Inflammation relapse was associated with the coexistence of pain as presenting sign (p<0.001) and with a longer duration of symptoms prior to the initial visit (p=0.023).	21398411
Inflammatory abnormality of the eye, Ocular syphilis, Vitritis, Vasculitis, CTCAE, Anterior uveitis	Altered Intercellular Communication	Severe ocular inflammation associated with vasculitis, vitritis or anterior uveitis in ocular syphilis would appear to be a reversible phenomenon that responds well to appropriate antibiotic treatment, resulting in improvement in visual acuity.	21398411
Toxocariasis, Inflammation	Altered Intercellular Communication	The toxocariasis was unilateral in all patients, and the inflammation was acute in two-thirds of the patients.	21400060
Inflammatory, Inflammation	Altered Intercellular Communication	The clinical manifestation is unilateral and presents as acute inflammation with a peripheral inflammatory mass.	21400060
Inflammation, Microcirculation, Edema	Altered Intercellular Communication	Early CMR in TTC demonstrates a special morphological pattern of late gadolinium uptake that might correspond to localized inflammation and edema in the affected area, suggesting diffuse microcirculation damage rather than epicardial vessel involvement.	21400545
Psoriasis	Altered Intercellular Communication	Psoriasis is a chronic inflammatory condition affecting 1-3% of the population.	21401376
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	Macrophage migration inhibitory factor (MIF) is one of key regulators in acute and chronic immune-inflammatory conditions including rheumatoid arthritis (RA).	21401926
Inflammation	Altered Intercellular Communication	The no-LT group had increased inflammation in the colonic mucosa at histology (p=0.011), but without visual difference at colonoscopy.	21402617
Inflammation, MS gene	Altered Intercellular Communication	Loss of braking signals during inflammation: a factor affecting the development and disease course of multiple sclerosis.	21403007
Inflammation	Altered Intercellular Communication	Defects in negative-feedback loops of inflammation lead to an overactivation of the immune system so as to predispose the brain to inflammation-sensitive MS.	21403007
Inflammation, Calcinosis, Aortic Valve Stenosis	Altered Intercellular Communication	The development of aortic valve stenosis is not only associated with calcification and extracellular matrix remodeling, but also with inflammation.	21403093
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	AOPPs level positively correlated with Child-Pugh score in alcohol-related cirrhosis but not in HCV-related cirrhosis and the correlation with the indices of chronic inflammation was stronger in ALC.	21403920
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	In turn, AOPPs in HCV-related cirrhosis was related to inflammation to a lesser extent, but a significant correlation with antioxidant defense could be noted.	21403920
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	The significant correlation between AOPPs accumulation and indices of chronic inflammation, more specifically TNF-a, suggests that oxidative stress may be a mediator of chronic inflammatory state in the early stage of alcohol-related cirrhosis.	21403920
Inflammation, Fibrosis Assessment, Nesidioblastosis	Altered Intercellular Communication	Histologic degree of fibrosis, acinar atrophy, inflammation, and nesidioblastosis were scored by a surgical pathologist.	21404456
Inflammation, Fibrosis Assessment, Atrophic	Altered Intercellular Communication	Fibrosis and acinar atrophy correlated negatively with islet yield (P < G 0.001, r =0.67), as did inflammation (P < G 0.001, r =0.43).	21404456
palladium, Inflammation, Synovial Hypertrophy	Altered Intercellular Communication	All US examinations were performed by two rheumatologists investigating: presence of joint cavity widening (JCW), synovial fluid and/or synovial hypertrophy, peritenon extensor tendon inflammation (PTI) and intra-articular or peri-tendinous power Doppler (PD) signal.	21406459
Inflammation, Calcaneal apophysitis	Altered Intercellular Communication	Sever's disease, also known as calcaneal apophysitis, is thought to be an inflammation of the apophysis of the heel, which is open in childhood.	21406697
Inflammation, Atherosclerosis	Altered Intercellular Communication	Growing evidence supports the role played by inflammation in atherosclerosis.	21407077
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	There is substantial evidence that inflammation within the central nervous system contributes to stroke risk and recovery.	21407237
Cerebrovascular accident	Altered Intercellular Communication	Inflammatory conditions increase stroke risk, and the inflammatory response is of major importance in recovery and healing processes after stroke.	21407237
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Pulmonary Complication	Altered Intercellular Communication	Circulating markers of inflammation in chronic obstructive pulmonary disease (COPD) may correlate to disease progression and extrapulmonary complications such as malnourishment.	21407820
ARCN1 gene, Inflammation	Altered Intercellular Communication	To characterize differences in circulating markers of inflammation in malnourished female and male patients with COPD.	21407820
ARCN1 gene, Inflammation, Malnutrition	Altered Intercellular Communication	Our study puts forward evidence of a gender-related difference in systemic inflammation in malnourished patients with COPD in terms of circulating neutrophils being more abundant in female patients.	21407820
Inflammation, Hematoma, Hypoxia	Altered Intercellular Communication	Human early fracture hematoma is characterized by inflammation and hypoxia.	21409457
Inflammation, Hematoma, Fracture, Hypoxia	Altered Intercellular Communication	Our data suggest cells in the fracture hematoma (1) adapt to hypoxia and (2) promote inflammation in fracture healing at the mRNA level, indicating early involvement of the immune system.	21409457
Pain Distress Question, Hemorrhage, Inflammation, Bowel sounds, Concretion of intestine, Flatulence, Obstruction, Malabsorption Syndrome	Altered Intercellular Communication	Clinically they may be asymptomatic or may give rise to symptoms like pain, flatulence and borborygmi, may produce malabsorption syndrome or may present in emergency with different acute pathologies like perforation, haemorrhage, obstruction, enterolith formation and inflammation.	21409932
Ileus, CTCAE, Inflammation, Pain Distress Question, Perforation (observation), Diverticulum	Altered Intercellular Communication	Eight out of 10 patients presented with perforation of diverticula while 1 patient had severe inflammation of diverticulum causing pain, ileus and acute abdomen.	21409932
Inflammation, Jejunal diverticula	Altered Intercellular Communication	Inflammation and adhesion are other complications with which jejunal diverticula presented during this study.	21409932
Autoimmune Diseases, Inflammation, VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)	Altered Intercellular Communication	Our study clearly shows that features of inflammation (pruritus)/autoimmunity (halo naevi, thyroid antibodies) are strongly linked to NSV, together with a familial background of vitiligo and autoimmunity.	21410675
Intradermal Route of Drug Administration	Altered Intercellular Communication	Obese individuals may be at increased risk of iron deficiency (ID), but it is unclear whether this is due to poor dietary iron intakes or to adiposity-related inflammation.	21411619
Intradermal Route of Drug Administration	Altered Intercellular Communication	This increased risk of ID may be due to the effects of obesity-related inflammation on dietary iron absorption.	21411619
Inflammation, Heart failure	Altered Intercellular Communication	Inflammation and serum oxidative stress (OS) are important components in heart failure (HF) deterioration.	21411994
Inflammation, Non-Small Cell Lung Carcinoma, Blood Vessel	Altered Intercellular Communication	We also identified several novel genes whose expression was downregulated in NSCLC, including SGCG, NLRC4, MMRN1, and SFTPD, which are involved in extracellular matrix formation, apoptosis, blood vessel leakage, and inflammation, respectively.	21412013
Autoimmune Diseases, Inflammation, Granulomatosis with polyangiitis	Altered Intercellular Communication	Wegener's granulomatosis (WG) is a complex autoimmune disease of unknown etiology, frequently involving localized inflammation of the nasal mucosa as an early manifestation.	21412229
Inflammatory Hepatocellular Adenoma, Cryoglobulinemia, SMN1 wt Allele	Altered Intercellular Communication	The presence of SMA and cryoglobulinemia was not associated with hepatocellular inflammation activity, age, carrier gender or HCV genotype.	21412592
Communicable Diseases, Inflammation, Parotitis	Altered Intercellular Communication	Chronic parotitis is a troubling clinical condition characterized by repeated infection and inflammation of the parotid gland caused by decreased salivary flow or obstruction.	21412726
Inflammation	Altered Intercellular Communication	Malacoplakia is an unusual chronic granulomatous inflammation that commonly occurs in the urinary tract.	21412727
Meningitis	Altered Intercellular Communication	Aseptic meningitis refers to a clinical syndrome of meningeal inflammation in which bacteria cannot be identified in the cerebrospinal fluid (CSF).	21412795
Dermatitis, Atopic, allergic inflammation, Disease	Altered Intercellular Communication	The capacity of microbial products to inhibit allergic inflammation make them logical candidates for novel therapies in allergic diseases such as atopic dermatitis.	21413940
Pressure Ulcer, Inflammation, Ischemia	Altered Intercellular Communication	Too strong and constant pressure caused by fixing clips led to skin ischemia, followed by inflammation and decubitus ulcer, and consequently to the penetration of clips into the earlobes.	21413962
Inflammation, Gastrointestinal mucositis	Altered Intercellular Communication	The most common complications for patients in both study and control group were soft tissue inflammation (mucositis).	21414134
Inflammation, Endothelial dysfunction, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	Endothelial dysfunction, inflammation and atherosclerosis in chronic kidney disease--a cross-sectional study of predialysis, dialysis and kidney-transplantation patients.	21414625
Inflammation, Endothelial dysfunction, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	Systemic inflammation may contribute to endothelial dysfunction and accelerated atherosclerosis in CKD patients.	21414625
Inflammation, Endothelial dysfunction, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	We assessed the relationship among, endothelial dysfunction, early atherosclerosis and inflammation in predialysis, dialysis and post kidney-transplantation CKD patients.	21414625
Inflammation, Endothelial dysfunction, atherosclerotic	Altered Intercellular Communication	Our findings suggest that endothelial dysfunction and atherosclerotic changes correlate with inflammation.	21414625
Inflammation, Communicable Diseases, Epithelial metaplasia, Irritation, Squamous metaplasia	Altered Intercellular Communication	The histogenesis of urothelial metaplasia in the seminal vesicle is unclear, but it possibly is a reaction to mechanical irritation, inflammation, or infection, as has been proposed for urothelial metaplasia in the fallopian tube and squamous metaplasia of the pelvic peritoneum.	21414821
Autistic Disorder, Gastrointestinal inflammation	Altered Intercellular Communication	Only 6% of autistic patients had intestinal inflammation.	21415091
Lactase deficiency (disorder), Pain Distress Question, Autistic Disorder, Gastrointestinal inflammation	Altered Intercellular Communication	Lactase deficiency not associated with intestinal inflammation or injury is common in autistic children and may contribute to abdominal discomfort, pain and observed aberrant behavior.	21415091
Diabetes Mellitus	Altered Intercellular Communication	Our results suggest that the metabolic and hormonal changes related to diabetes may play a role in the etiology of GCA independently from BMI.	21415356
Inflammation, Malignant neoplasm of endometrium, Obesity	Altered Intercellular Communication	It is hypothesized that inflammation may mediate the relationship between obesity and endometrial cancer risk.	21415362
Inflammation, Tumor necrosis, Malignant neoplasm of endometrium	Altered Intercellular Communication	We examined the associations of three inflammation markers, C-reactive protein (CRP), interleukin (IL)-6 and tumor necrosis factor (TNF)-a, with risk of endometrial cancer.	21415362
Increased insulin level, Inflammation, Malignant neoplasm of endometrium	Altered Intercellular Communication	The association between inflammation, as indicated by a relatively high level of CRP, and endometrial cancer risk may partially be explained by hyperinsulinemia and elevated estradiol.	21415362
Inflammation, Malignant neoplasm of endometrium, Obesity	Altered Intercellular Communication	The association between obesity and endometrial cancer risk in postmenopausal women may be attributed to inflammation, insulin resistance, and elevated estrogen.	21415362
Granulomatous inflammation, Pleurisy, Vasculitis, CTCAE, Geographic Necrosis	Altered Intercellular Communication	Other pathologic findings included granulomatous inflammation with geographic necrosis (3), vasculitis (3), and pleuritis (3).	21415702
Inflammation, Edema, Pain Distress Question	Altered Intercellular Communication	Endplate signal abnormalities, particularly M1 changes indicating edema and inflammation, have been suggested to play an important role in the etiopathogenesis of a subgroup of patients with nonspecific chronic low back pain (CLBP).	21415809
Inflammation	Altered Intercellular Communication	The incidences of chronic inflammation in 1 and 2 g/kg males and females were significantly increased.	21415873
Acute and chronic inflammation	Altered Intercellular Communication	A significantly increased incidence of chronic active inflammation of the nose occurred in 0.5 g/kg males.	21415873
Acute and chronic inflammation	Altered Intercellular Communication	Also in 0.5 g/kg males, the incidence of chronic active inflammation of the forestomach was increased.	21415873
Inflammation, Hyperplasia	Altered Intercellular Communication	In the forestomach, there were significantly increased incidences of inflammation and epithelial hyperplasia in 0.5 g/kg females.	21415873
Inflammation, Takotsubo Cardiomyopathy	Altered Intercellular Communication	Platelet and monocyte activity markers and mediators of inflammation in Takotsubo cardiomyopathy.	21416113
Inflammation, CD55 gene	Altered Intercellular Communication	We analyzed blood concentrations of mediators of inflammation and platelet- and monocyte-activity markers in patients with TC and MI for significant differences.	21416113
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	Cytoskeletal modification and inflammation are known to occur during the pathogenesis of ALS.	21418221
Inflammation, Metabolic Syndrome X, Hostility	Altered Intercellular Communication	Hostility, metabolic syndrome, inflammation and cardiac control in young adults: The Young Finns Study.	21419189
Inflammation, Metabolic Syndrome X, Cardiovascular Diseases, Hostility, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	We studied whether there is an association between hostility and cardiovascular heart disease (CHD) risk factors, such as the metabolic syndrome, systemic inflammation and autonomic cardiac control.	21419189
Inflammation, Metabolic Syndrome X, Hostility	Altered Intercellular Communication	In women, hostility predicted increased risk of metabolic syndrome (EGIR, and the IDF definitions, ORs = 1.34, 1.35, p < 0.05), and higher levels of inflammation (b = 0.09, p < 0.01).	21419189
Inflammation, Hostility, Metabolic Syndrome X, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	We concluded that hostility is associated with metabolic syndrome and systemic inflammation in women and these conditions may be factors linking hostility to CHD.	21419189
Polyarteritis Nodosa	Altered Intercellular Communication	Most cases (n = 14) showed polyarteritis nodosa (PAN)-like features with transmural necrotizing inflammation of small-medium arteries.	21419476
Pyuria, prostatitis	Altered Intercellular Communication	Prostatic inflammation detected in initial biopsy specimens and urinary pyuria are predictors of negative repeat prostate biopsy.	21420119
prostatitis	Altered Intercellular Communication	Asymptomatic prostatic inflammation may cause increased prostate specific antigen in some men, leading to unnecessary repeat prostate biopsy.	21420119
Inflammation, Pyuria	Altered Intercellular Communication	Age, prostate specific antigen density, polymorphonuclear leukocyte inflammation in initial biopsy specimens and urinary pyuria are indicators of benign repeat biopsy.	21420119
Airway structure, Asthma	Altered Intercellular Communication	Prenatal smoke exposure is associated with airway inflammation and asthma in children.	21422092
Airway structure	Altered Intercellular Communication	Plausibly, airway inflammation from prenatal smoke exposure induces obstructive symptoms more easily in the underdeveloped airways of LBW children.	21422092
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Punch biopsy specimens demonstrated interstitial dermal granulomatous inflammation.	21422341
Inflammation, Fibrous, Granulation finding	Altered Intercellular Communication	Four phases of physiological healing were observed: platelet and fibrin deposition, inflammation, granulation tissue, and finally, fibrous encapsulation.	21422390
Inflammation	Altered Intercellular Communication	In addition to its function in calcium and bone metabolism, vitamin D is neuroprotective and important for mitigating inflammation.	21422528
Inflammation, Systemic Vasculitis	Altered Intercellular Communication	This is the first reported case of epidural inflammation ascribed to microscopic polyangiitis.	21422637
Acute Lung Injury, Inflammation	Altered Intercellular Communication	We therefore sought to determine whether enteral fish oil alone would reduce pulmonary and systemic inflammation in patients with acute lung injury.	21423000
Acute Lung Injury, Inflammation	Altered Intercellular Communication	Fish oil did not reduce biomarkers of pulmonary or systemic inflammation in patients with acute lung injury, and the results do not support the conduct of a larger clinical trial in this population with this agent.	21423000
Perifolliculitis	Altered Intercellular Communication	Taking the findings of both eyes, the prevalence of trachomatous inflammation-follicular (TF) in children aged 1-9 years was 25.1% (96/383) of whom 13 (13.7%) were PCR positive on the left eye.	21423648
Inflammation	Altered Intercellular Communication	The cytokine interleukin-10 (IL-10) has a central role in mediating inflammation, which may affect the outcome of the patients with GD.	21424183
Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation-sensitive proteins and risk of atrial fibrillation: a population-based cohort study.	21424216
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding, Cardiovascular Diseases	Altered Intercellular Communication	Low-grade inflammation has been repeatedly associated with cardiovascular diseases but the relationship with incidence of atrial fibrillation (AF) remains unclear.	21424216
Inflammation, Ischemic stroke	Altered Intercellular Communication	There is increasing evidence that inflammation plays an important role in the progression of acute ischemic stroke (AIS).	21424610
Carcinogenesis	Altered Intercellular Communication	It is believed that the host genetic factors such as inflammation-induced cytokines may play a role in cervical carcinogenesis.	21424904
Inflammation, Hemorrhage, fiber, Thickened, Trauma, Nervous System, Chemical injury, Vasculitis	Altered Intercellular Communication	Nerve biopsies were similar to DLPRN showing ischemic injury (multifocal fiber loss [11/23], perineural thickening [18/23], injury neuroma [11/23], neovascularization [17/23]) and evidence of altered immunity and microvasculitis (epineurial perivascular inflammation [23/23], prior bleeding [11/23], vessel wall inflammation [15/23], and microvasculitis [3/23]).	21425185
Colorectal Carcinoma, Acute and chronic inflammation, Ulcerative Colitis	Altered Intercellular Communication	Patients with extensive, longstanding ulcerative colitis (UC), a disease of chronic colonic inflammation, are at risk for colorectal cancer (CRC).	21425209
Inflammation	Altered Intercellular Communication	Elucidating the mechanism and fully characterizing the nature of this chronic inflammation offers the potential to identify those at greatest risk.	21425209
Cyst, Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	The cyst contents appeared clear and no secondary inflammation or glaucoma occurred.	21425755
Inflammation, Chronic Obstructive Airway Disease, Erectile dysfunction	Altered Intercellular Communication	The increased prevalence of erectile dysfunction (ED) has been reported in patients with chronic obstructive pulmonary disease, and sustained systemic inflammation seems to play a central role in this linkage.	21426497
Inflammation, Asthma, Inflammatory disorder	Altered Intercellular Communication	Asthma is also a chronic inflammatory airway disorder, eliciting a low-grade systemic inflammation; however, the influence of asthma on ED has not been investigated.	21426497
Airway structure, Chronic cough	Altered Intercellular Communication	To explore the relationship between airway inflammation and Toll-like receptor 2 (TLR2) expression on macrophages in induced sputum from chronic cough patients, and to observe the effect of methylprednisolone on this receptor.	21426732
Inflammation, Malnutrition, Depression, CTCAE, Neutrophil count decreased, Chronic Kidney Diseases	Altered Intercellular Communication	We suspected severe immunosuppression caused by various factors, such as predonisolone administration, chronic renal failure on maintenance hemodialysis, depression, and malnutrition due to chronic inflammation and granulocytopenia as a side effect of ganciclovir.	21426895
Inflammation, Dyslipidemias, Overweight	Altered Intercellular Communication	In this population, high RBC EPA and DHA were associated with attenuated dyslipidemia and low-grade systemic inflammation among overweight and obese persons.	21427737
Granulomatous inflammation, Granulomatosis with polyangiitis, Necrosis	Altered Intercellular Communication	Wegener's granulomatosis is a necrotic, granulomatous inflammation of small vessels of the upper and lower airways and kidneys.	21427813
Communicable Diseases, Inflammation, Peri-Implantitis	Altered Intercellular Communication	In the context of peri-implantitis, TNC might be a marker of bone remodelling rather than inflammation and infection.	21429069
Acute Lung Injury, Pneumonitis	Altered Intercellular Communication	Hepatocyte growth factor (HGF) is known to be involved in the resolution of pulmonary inflammation and repair of acute lung injury.	21429184
Inflammation, Nasopharyngeal carcinoma, Nasopharynx, Angiolymphoid hyperplasia, Papilloma	Altered Intercellular Communication	Of all cases, there were 1 of papilloma, 87 of lymphoid follicular hyperplasia and chronic inflammation, 11 of nasopharyngeal cysts, and 25 of nasopharyngeal carcinoma.	21429337
Narrow Band Imaging, Inflammation, Nasopharynx, Angiolymphoid hyperplasia, Papilloma	Altered Intercellular Communication	Under NBI, the color depths were (+) in papilloma, (++) in nasopharyngeal cysts, and (+++) in lymphoid follicular hyperplasia and chronic inflammation, without abnormal vessels.	21429337
Cessation of life, Inflammation, Obesity, Cerebrovascular accident	Altered Intercellular Communication	Adiposity, inflammation, and risk for death in black and white men and women in the United States: the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study.	21430022
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Genetic polymorphisms in inflammation pathway genes and prostate cancer risk.	21430300
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Chronic inflammation is an important mechanism for the development and progression of prostate cancer (PC).	21430300
Inflammation	Altered Intercellular Communication	These results suggest that variants in genes within the inflammation pathway may play a role in the development of PC, however, further studies are needed to replicate our findings.	21430300
Inflammation, Allergic	Altered Intercellular Communication	IL-13 is a major stimulator of inflammation and tissue remodeling at sites of Th2 inflammation, and common single-nucleotide polymorphisms in IL13 are associated with allergic phenotypes in several ethnically diverse populations.	21430433
allergic inflammation	Altered Intercellular Communication	IL13Q110 has been demonstrated to show that increased allergic inflammation depended on the enhanced IL-13-mediated Th2 effector function.	21430433
Airway structure	Altered Intercellular Communication	To analyze airway inflammation and remodeling, bronchial lavage fluid (BLF) and endobronchial biopsy specimens were examined.	21430433
allergic inflammation	Altered Intercellular Communication	Our study demonstrates that Q110/Q110 increases, at least in part, allergic inflammation and the propensity for airway remodeling, thus resulting in low lung function.	21430433
Inflammation	Altered Intercellular Communication	IL-1b might be inducing RA inflammation through producing pro-inflammatory IL-33 in TNF inhibitor-hypo-responders.	21431944
Necrotizing granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	Excision biopsy and histopathologic examination revealed necrotizing granulomatous inflammation suggestive of tuberculosis.	21434554
Hypotension, CTCAE, Ocular Hypotension, Leprosy, Intraocular inflammation	Altered Intercellular Communication	Transient hypotension and hypotony in MB leprosy patients are associated with signs of intraocular inflammation.	21434594
Rheumatoid Arthritis, Arthritis, Erosion of bone	Altered Intercellular Communication	TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis.	21435232
Refractory anemias, Inflammation, Rheumatoid Arthritis, Erosion of bone	Altered Intercellular Communication	TNF-like weak inducer of apoptosis (TWEAK) has been proposed as a mediator of inflammation and bone erosion in rheumatoid arthritis (RA).	21435232
Refractory anemias, Inflammation, Erosion of bone	Altered Intercellular Communication	High levels of sTWEAK in active RA synovial fluid and of TWEAK and Fn14 in active RA tissue, together with the effect of TWEAK to induce osteoblastic RANKL expression, is consistent with TWEAK/Fn14 signalling being important in the pathogenesis of inflammation and bone erosion in RA.	21435232
Inflammation, Atherosclerosis	Altered Intercellular Communication	Quantification of coronary atherosclerosis and inflammation to predict coronary events and all-cause mortality.	21435514
Inflammation, SLC25A20 gene, Dental Plaque	Altered Intercellular Communication	Both hsCRP as a measure of inflammation and CAC as a measure of coronary plaque burden have been shown to improve risk appraisal.	21435514
Coronary Artery Disease, Acute inflammation	Altered Intercellular Communication	Framingham risk variables, hsCRP, and CAC were measured in 3,966 subjects without known coronary artery disease or acute inflammation.	21435514
Inflammation, SLC25A20 gene, Atherosclerosis	Altered Intercellular Communication	The risk of coronary events and all-cause mortality that is mediated by the presence of coronary atherosclerosis and systemic inflammation can be estimated by CAC and hsCRP.	21435514
Inflammation, Perforation (observation), Boerhaave syndrome	Altered Intercellular Communication	The results of this study suggest that thoracoscopic esophageal repair may be a good surgical alternative in patients with Boerhaave's syndrome who have a relatively stable vital sign or mild inflammation, regardless of the time interval between perforation and surgery.	21435633
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Increased angiogenesis, chronic inflammation, and extracellular matrix degradation are the major pathological features of abdominal aortic aneurysm (AAA).	21436157
Inflammation, Pneumonia	Altered Intercellular Communication	Increased lung neutrophil apoptosis and inflammation resolution in nonresponding pneumonia.	21436352
Inflammation	Altered Intercellular Communication	After 72 h of treatment, an increased basal alveolar neutrophil apoptosis might contribute to downregulation of inflammation and to faster clinical stability.	21436352
Pain Distress Question, Bone Marrow Diseases, Proliferative inflammation	Altered Intercellular Communication	HSP is a rare disease characterized by hypertrophic inflammation of the dura mater and clinical symptoms that progress from local pain to myelopathy.	21436740
Bone Diseases, Inflammation	Altered Intercellular Communication	Association of ankle-arm index with inflammation and mineral bone disorder in hemodialysis patients.	21437516
Inflammation, Metabolic Bone Disorder, HD Term Type, Bone Diseases, Cardiac complication, Cessation of life	Altered Intercellular Communication	Reduced ankle-arm index (AAI), inflammation and mineral bone disorder (MBD) are all associated with increased risk of death and cardiovascular complications in patients on hemodialysis (HD), but the association between them deserves clarification.	21437516
HD Term Type, Inflammation	Altered Intercellular Communication	To evaluate the association between abnormal AAI with MBD and inflammation in patients on HD.	21437516
Inflammation	Altered Intercellular Communication	The risk of having low AAI seems to be increased by aging and inflammation, whereas BMD was associated with high AAI.	21437516
Inflammation, Normocytic anemia, microcytic	Altered Intercellular Communication	To examine the impact of a body fat content on the concentration of a serum prohepcidin, iron metabolism parameters and inflammation markers in elderly patients with microcytic or normocytic anemia.	21437556
Airway structure, Asthma, Asthma attack	Altered Intercellular Communication	Treating children asthma by integrated traditional Chinese and western medicine can obviously reduce IL4 and IL-13, increase IFN-gamma, and therefore lighten the airway inflammation, prevent asthma attacks effectively.	21438413
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome is associated with higher C-reactive protein (CRP) serum levels, a common biological marker of inflammation.	21438714
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	However, the respective contribution of each component of metabolic syndrome to the inflammation has not been established.	21438714
Hereditary Autoinflammatory Diseases, Inflammation, Fever, CTCAE, Brucellosis, Familial Mediterranean Fever	Altered Intercellular Communication	Familial Mediterranean fever (FMF) is an autoinflammatory disease characterized by recurrent episodes of fever and serosal or synovial inflammation.	21438869
Gastrointestinal inflammation	Altered Intercellular Communication	Chemokine CXCL11 links microbial stimuli to intestinal inflammation.	21438871
Gastrointestinal inflammation	Altered Intercellular Communication	In a skewed Th1 response environment flagellin induces intestinal inflammation, with IL-17 expression predominant.	21438871
Gastrointestinal inflammation	Altered Intercellular Communication	CXCR3/CXCL11 pathway is involved in microbial product flagellin-induced intestinal inflammation in which the Th17 response plays an important role.	21438871
Waldenstrom Macroglobulinemia, Atrophic	Altered Intercellular Communication	Microscopically, all CSS-cases showed similar morphology with preservation of lobular architecture accentuated by cellular fibrous bands, dense lymphoplasmacytic inflammation and varied acinar atrophy.	21438912
Pain Distress Question, Inflammation	Altered Intercellular Communication	Canakinumab 150 mg provided significantly greater and more rapid reduction in pain and signs and symptoms of inflammation compared with triamcinolone acetonide 40 mg.	21439048
Airway structure, Asthma	Altered Intercellular Communication	Fractionated exhaled nitric oxide (FeNO) expression is increased in airway inflammation and several studies have suggested that FeNO measurement can be useful in patients with asthma.	21439165
Inflammation, Malnutrition	Altered Intercellular Communication	In this respect, the association between malnutrition and inflammation may be a confounding factor in the determination of the true relationship between Hcy, nutritional status, and cardiovascular risk factors in this group.	21439851
Inflammation	Altered Intercellular Communication	Hemodialysis induces p66(shc) gene expression in nondiabetic humans: correlations with oxidative stress and systemic inflammation.	21439852
Inflammation, Malnutrition, Cardiovascular Diseases	Altered Intercellular Communication	Oxidative stress and inflammation characterize hemodialysis (HD) and are associated with malnutrition, cardiovascular disease, and poor clinical outcome.	21439852
HD Term Type, Inflammation	Altered Intercellular Communication	p66(shc) messenger ribonucleic acid (mRNA) was compared with systemic oxidative stress and inflammation markers in control subjects and patients on HD before and after a single HD session in a cross-sectional analysis.	21439852
Perineural spread, Inflammation	Altered Intercellular Communication	The incidence of angiolymphatic invasion, visceral pleural invasion, and degree of tumor inflammation, as well as morbidity, mortality, and length of stay were similar between segmentectomy and lobectomy.	21440123
Inflammation	Altered Intercellular Communication	There was a trend for decreased recurrence with increasing tumor inflammation (mild versus severe, p = 0.066).	21440123
Inflammation, Neoplasms	Altered Intercellular Communication	The clinical course of the patient suggests that the tumor produced interleukin-6 and this was associated not only with inflammation, but also the aggressive biologic behavior of the tumor.	21440168
Chronic sinusitis, Craniosynostosis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	It is unclear whether mucosal inflammation has an effect on the bone under the mucosa in patients with chronic rhinosinusitis (CRS).	21442077
Inflammation, Malnutrition	Altered Intercellular Communication	Inflammation can lead to malnutrition to some extent.	21442152
Refractory anemias, Inflammation, Rheumatoid Arthritis, Atherosclerosis	Altered Intercellular Communication	Systemic inflammation may be a common process that underpins both atherosclerosis and extra-articular features (ExRA) of rheumatoid arthritis (RA).	21442165
Inflammation, Bacterial resistance	Altered Intercellular Communication	Based on other work regarding intestinal bacteria, we hypothesize a relationship between chronic inflammation of the appendix from bacterial overgrowth and Ki-ras gene mutation.	21443421
Inflammation, Primary malignant neoplasm, Cardiovascular Diseases	Altered Intercellular Communication	Food patterns, inflammation markers and incidence of cardiovascular disease: the Malmo Diet and Cancer study.	21443679
Heart Diseases, Inflammation	Altered Intercellular Communication	Systemic inflammation (SI) is associated with impairment of cardiac autonomic modulation (CAM), which is associated with cardiac disease.	21444250
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	There was no association with a panel of CHD biomarkers, including any lipid, inflammation, or coagulation trait, nor with telomere length.	21444365
Inflammation, Bacterial Infections	Altered Intercellular Communication	Thus, we propose that secretion of AGEs by bacteria is a novel avenue of bacterial-induced inflammation which is potentially important in the pathophysiology of bacterial infections.	21445354
Inflammation	Altered Intercellular Communication	These findings provide evidence that neurons in MS are respiratory-deficient due to mtDNA deletions, which are extensive in GM and may be induced by inflammation.	21446022
Narcolepsy	Altered Intercellular Communication	Similarly to that reported in patients with narcolepsy, the cortical hypoexcitability may reflect the deficiency of the excitatory hypocretin/orexin-neurotransmitter system.	21446790
Primary Myelofibrosis, Inflammation	Altered Intercellular Communication	The interferon signature may reflect primary myelofibrosis as the burn-out phase of chronic inflammation which ultimately elicits clonal evolution and expansion owing to an exaggerated but incompetent antitumor immune response.	21447007
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Airway inflammation in chronic obstructive pulmonary disease (COPD) is believed to be insensitive to corticosteroids.	21447053
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Histological studies support the important role of inflammation in the initiation and maintenance of atrial fibrillation (AF).	21447517
Panniculitis	Altered Intercellular Communication	We describe a novel and safe technique of atrial biopsy during AF radiofrequency catheter ablation (RFCA) to investigate the role of atrial tissue inflammation.	21447517
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Variants of gene for microsomal prostaglandin E2 synthase show association with disease and severe inflammation in rheumatoid arthritis.	21448233
Refractory anemias, Inflammation	Altered Intercellular Communication	Our data reveal a possible influence of PTGES polymorphism on the pathogenesis of RA and on disease severity through upregulation of mPGES-1 at the sites of inflammation.	21448233
Chronicity, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings.	21448457
Inflammation	Altered Intercellular Communication	When telomeres critically shorten, as often occurs with repeated mitoses or in response to oxidation and inflammation, cells may die.	21448457
Minimal Disseminated Disease, Depressive disorder, Inflammation, Depression, CTCAE	Altered Intercellular Communication	We sought to determine if leukocyte telomeres are shortened in Major Depressive Disorder (MDD), whether this is a function of lifetime depression exposure and whether this is related to putative mediators, oxidation and inflammation.	21448457
Inflammation, Depressed mood	Altered Intercellular Communication	Telomere length was inversely correlated with oxidative stress in the depressed subjects (p<0.01) and in the controls (p<0.05) and with inflammation in the depressed subjects (p<0.05).	21448457
Minimal Disseminated Disease, Inflammation	Altered Intercellular Communication	This might be related to cumulative exposure to oxidative stress and inflammation in MDD.	21448457
Kidney Failure, Chronic, Inflammation, Metabolic Diseases, Protein-Energy Malnutrition	Altered Intercellular Communication	Protein-energy malnutrition, systemic inflammation, and metabolic disorders are frequent among patients with chronic kidney failure undergoing dialysis, contributing to their morbidity and mortality.	21448521
Inflammation, Dental Plaque	Altered Intercellular Communication	Also PCR has an important role such as marker of plaque stability and of inflammation.	21448539
Dyspnea, Airway structure	Altered Intercellular Communication	The highest-rated problems were dyspnoea, activity limitation and airway inflammation, and these areas had good patient-physician concordance.	21448550
ARCN1 gene, Asthma, Dyspnea, Airway structure	Altered Intercellular Communication	In asthma and COPD, patients and their physicians agree about the importance of managing activity limitation, dyspnoea, and airway inflammation.	21448550
Steatohepatitis, Weight decreased, Inflammation	Altered Intercellular Communication	BIA deserves more investigations concerning liver steatosis and ongoing inflammation, and it could contribute as well, synergistically with anthropometry, to monitor weight loss, body fat shifts, and metabolic risk.	21448907
vascular inflammations	Altered Intercellular Communication	Plasma levels of eight mediators of vascular inflammation and endothelial activation, sampled from different vascular compartments.	21450032
glycation, Inflammation	Altered Intercellular Communication	The receptor for advanced glycation end products (RAGE) is a multiligand signal transduction receptor that can initiate and perpetuate inflammation.	21450080
Inflammation, Chronic heart failure, Endothelial dysfunction, Congestive heart failure	Altered Intercellular Communication	A reciprocal link between inflammation, oxidative/nitrosative stress, and endothelial dysfunction has been postulated in chronic heart failure (CHF).	21450636
Sjogrens Syndrome", PEELING SKIN SYNDROME	Altered Intercellular Communication	Primary Sjogren's syndrome (pSS) is characterised by a chronic inflammation of exocrine glands.	21450750
Arteritis	Altered Intercellular Communication	In particular, IL-32 seems to be an important mediator of artery inflammation in GCA.	21452292
Inflammation, Ichthyosis Bullosa of Siemens, Irritable Bowel Syndrome, Cell Stress Process	Altered Intercellular Communication	Irritable bowel syndrome (IBS) is a stress-related disorder with disturbed brain-gut communication, gastrointestinal homeostasis and, based on recent evidence, low grade inflammation and an altered microbiota.	21453321
Inflammation	Altered Intercellular Communication	The budesonide-soaked Merocel MMS showed a trend toward reduced mucosal inflammation when compared to the control Merocel MMS, but the results were not statistically significant.	21453656
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Molecular mechanisms of inflammation during exacerbations of chronic obstructive pulmonary disease.	21454005
Inflammation	Altered Intercellular Communication	Moreover, C pneumoniae-specific IgG was significantly correlated with hsCRP among ACAD patients, suggesting an important role of these organisms in the development of CAD by altering lipid profile and induction of inflammation.	21454155
Inflammation	Altered Intercellular Communication	C-C motif ligand 3 (CCL3) chemokine plays a crucial role in the inflammation process, cell migration and chemoattraction of monocytes/macrophages, neutrophils and mast cells.	21454208
ARCN1 gene, Airway structure	Altered Intercellular Communication	Seventy-five patients with COPD (58 men, 17 women) were studied with CT imaging and with measures of airway inflammation.	21454400
Airway structure	Altered Intercellular Communication	There was no difference in airway inflammation, exacerbation frequency, or bacterial load in patients with EM alone or with BE and/or BWT +- EM.	21454400
ARCN1 gene, Inflammation	Altered Intercellular Communication	Adenosine and related purines have established roles in inflammation, and elevated airway concentrations are predicted in patients with COPD.	21454402
Inflammation, Tooth Loss, Impaired cognition	Altered Intercellular Communication	Several mechanisms may associate tooth loss and related oral inflammation with cognitive impairment.	21454843
Inflammation	Altered Intercellular Communication	In the PRT group, mid-tibia muscle cross-sectional area increased less in men with higher pre-training inflammation compared with those men with lower inflammation (net difference ~2.5%, p < 0.05).	21455612
Inflammation, Muscle hypertrophy	Altered Intercellular Communication	Furthermore, low-grade inflammation at baseline restricted muscle hypertrophy following PRT.	21455612
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The fact that no correlation was found between mucosal hydrophobicity and disease activity may indicate that the loss of mucosal hydrophobicity in UC is not exclusively a secondary effect due to inflammation.	21455745
Inflammation, Anemia	Altered Intercellular Communication	Moreover, we found that decrease in the renal function, duration of mHD, and inflammation may contribute to these above-mentioned changes, which are probably the factors that should be taken into account when explaining the mechanisms of persistence of anaemia in haemodialysed patients.	21455763
Inflammation	Altered Intercellular Communication	Histopathological signs of inflammation involved the right colon in 86% of patients and were purely right-sided in 23%.	21456044
Inflammation	Altered Intercellular Communication	The findings of inflammation were higher in the right compared to the left colon (P < 0.001), but the general inflammatory activity was low.	21456044
Inflammation, Malignant Neoplasms, Colitis	Altered Intercellular Communication	PSC-IBD may represent a distinct entity of colitis in which low endoscopic activity may mask an active histologic inflammation that possibly contributes to an increased risk of malignancy.	21456044
Colitis	Altered Intercellular Communication	Circumstances related to liver transplantation seem to act favorably on colonic inflammation in PSC.	21456044
Inflammation, Impaired T cell function	Altered Intercellular Communication	Also, patients suffer from b-cell dysfunction, chronic systemic inflammation, increased hormonal visceral adipose tissue activity, and an increased risk of cardiovascular events.	21457065
Inflammation, Impaired T cell function	Altered Intercellular Communication	Also, patients suffer from b-cell dysfunction, chronic systemic inflammation, increased hormonal visceral adipose tissue activity, and an increased risk of cardiovascular events.	21457065
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Reduced glomerular filtration rate, inflammation and HDL cholesterol as main determinants of superoxide production in non-dialysis chronic kidney disease patients.	21457070
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Serum ferritin is a discriminant marker for both fibrosis and inflammation in histologically proven non-alcoholic fatty liver disease patients.	21457446
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Metabolic Syndrome X	Altered Intercellular Communication	We evaluated serum ferritin and the features of metabolic syndrome with respect to histological inflammation and/or fibrosis in NAFLD patients.	21457446
Inflammation, Fibrosis Assessment, Diabetes Mellitus, Fatty Liver Disease	Altered Intercellular Communication	Multivariate regression showed that diabetes, serum ferritin concentrations, body mass index (BMI) and AST were independently associated with NASH: together, the areas under the receiver operating characteristic (AUROC) was 0.91 (95% confidence interval 0.86-0.96); fibrosis was associated with ferritin concentrations and BMI: AUROC 0.87, portal inflammation with ferritin and DM: AUROC 0.82, while lobular inflammation was associated with BMI, DM and ferritin: AUROC 0.85.	21457446
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Serum ferritin concentrations and BMI are strongly associated with fibrosis, portal and lobular inflammation in NAFLD patients.	21457446
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Both ferritin and BMI are potential discriminant markers to select patients for liver biopsy and are associated with inflammation and fibrosis.	21457446
Acute Coronary Syndrome, vascular inflammations, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	To identify systemically detectable vascular inflammation associated to redox system unbalance, advanced oxidation protein products (AOPP), formed by HClO reaction with proteins, Thiol levels, and their ratio (AOPP/Thiol ratio) were measured in patients with acute coronary syndromes (ACS).	21458436
Airway structure, Fibromuscular Dysplasia	Altered Intercellular Communication	The aim of the present study is to determine whether increased levels of PGE(2) from NAEB sputum supernatants play a protective role in airway inflammation and muscular hyperplasia.	21458581
Airway structure, Communicable Diseases, Lung Injury	Altered Intercellular Communication	These help establish a 'vicious cycle' of impaired mucociliary clearance, infection, airway inflammation and progressive lung injury.	21458739
Inflammation	Altered Intercellular Communication	Increased UACR was not associated with markers of inflammation or of renin angiotensin aldosterone system activation and was not reduced by aliskiren.	21459891
Inflammation, Fibrosis Assessment, Aortic Stiffness	Altered Intercellular Communication	Hepatic stiffness, relative fat fraction, inflammation grade, and fibrosis stage were assessed from MR elastography, in-phase and out-of-phase gradient-echo imaging, and liver biopsy histopathologic review, respectively.	21460032
Inflammation, Fibrosis Assessment, Fatty degeneration, Aortic Stiffness	Altered Intercellular Communication	The mean hepatic stiffness for patients with simple steatosis (2.51 kPa) was less (P = .028) than that for patients with inflammation but no fibrosis (3.24 kPa).	21460032
Fibrosis, Liver, Inflammation, Fibrosis Assessment, Aortic Stiffness	Altered Intercellular Communication	The mean hepatic stiffness for patients with inflammation but no fibrosis was less (P = .030) than that for patients with hepatic fibrosis (4.16 kPa).	21460032
Inflammation, Steatohepatitis, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Aortic Stiffness, Liver Stiffness	Altered Intercellular Communication	In patients with NAFLD, hepatic stiffness measurements with MR elastography can help identify individuals with steatohepatitis, even before the onset of fibrosis; NAFLD patients with inflammation but no fibrosis have greater liver stiffness than those with simple steatosis and lower mean stiffness than those with fibrosis.	21460032
Inflammation, Edema	Altered Intercellular Communication	On initial examination, he presented with a stromal edema involving the inferior half of the cornea, epithelial microcysts, and moderate chamber inflammation.	21461226
Inflammation, Corneal edema	Altered Intercellular Communication	One month after the initial visit, anterior chamber inflammation was improved and his visual acuity recovered to 20/20, but subtle corneal edema still remained.	21461226
Hypospadias, Diabetes Mellitus, Cryptorchidism, Obesity	Altered Intercellular Communication	Maternal obesity, which increases risk of diabetes and could influence hormone levels, may, therefore, be associated with risk of hypospadias and cryptorchidism.	21462299
Inflammation, Infection	Altered Intercellular Communication	Malakoplakia is an inflammation which is thought to develop secondary to chronic Escherichia coli infections.	21463841
Inflammation	Altered Intercellular Communication	Our previous studies have shown that exposure to inflammatory stimuli resulted in elevated LCN2 levels in brain microglia and astrocytes implicating LCN2 in brain inflammation.	21463871
Inflammation, millicurie, Data types - Address	Altered Intercellular Communication	MCI represents a prodromal stage of AD, and inflammation occurs as one of the earliest pathological events in AD.	21463871
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	Markers of inflammation in relation to long-term cardiovascular mortality in patients with lower-extremity peripheral arterial disease.	21463908
Rupture, vascular inflammations, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Elevated levels of inflammatory mediators reflect vascular inflammation, and play a significant role in the genesis of atherosclerosis, plaque instability and rupture.	21463908
Stargardts disease", Inflammation	Altered Intercellular Communication	Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration.	21464132
Inflammation	Altered Intercellular Communication	Age-related macular degeneration, a prevalent blinding disease of the elderly, is strongly associated with mutations in the genes for complement regulatory proteins (CRP), causing chronic inflammation of the RPE.	21464132
Inflammation, ABCA4 gene	Altered Intercellular Communication	Thus, Stargardt disease and age-related macular degeneration may both be caused by chronic inflammation of the RPE.	21464132
Atherogenesis, Inflammation, Acute myocardial infarction, Congenital Abnormality	Altered Intercellular Communication	On the basis of the role of activin A in inflammation, atherogenesis, and glucose homeostasis, we investigated whether activin A could be related to glucometabolic abnormalities in patients with acute myocardial infarction (MI).	21464440
Inflammation, Hyperglycemia	Altered Intercellular Communication	Our in vitro findings suggest that this association represents a counteracting mechanism to protect against inflammation, hyperglycemia, and oxidative stress.	21464440
Inflammation, Atherosclerosis	Altered Intercellular Communication	L-selectin is a member of the selectin family of cell adhesion molecules which are important in the transient attachment of leukocytes to endothelial cells, which plays a role in inflammation processes and is one of the earliest events in the pathogenesis of atherosclerosis.	21465128
Inflammation, Irritation - emotion, Dental caries	Altered Intercellular Communication	These findings are a confirmation that denticles appear during chronic inflammation as the consequence of pulp irritation caused by caries or fillings.	21465852
Adenocarcinoma	Altered Intercellular Communication	The most frequent diagnosis was adenocarcinoma mostly of pancreas followed by chronic granulomatous inflammation of mediastinal and abdominal lymph nodes.	21465975
Inflammation	Altered Intercellular Communication	Data indicate that levels of FAs and their composition may influence myocardial function and inflammation.	21466599
Inflammation	Altered Intercellular Communication	(iii) These changes in FA composition were significantly associated with functional class, impaired cardiac function (i.e., decreased cardiac index and increased plasma N-terminal pro-B-type natriuretic peptide levels) and enhanced systemic inflammation (i.e., increased high-sensitivity C-reactive protein levels).	21466599
Sepsis, Inflammation, Adrenal cortical hypofunction	Altered Intercellular Communication	This finding might have impact on interpreting previous and designing future trials on diagnosing and modulating immunoendocrine dysregulation (for example, adrenal insufficiency) during systemic inflammation and sepsis.	21466684
Inflammation, Cell Death	Altered Intercellular Communication	Activation of factor VII-activating protease in human inflammation: a sensor for cell death.	21466697
Sepsis, Inflammation	Altered Intercellular Communication	Circulating nucleosomes were suggested to play an important role in inflammation and were demonstrated to correlate with severity and outcome in sepsis patients.	21466697
Cessation of life, Inflammation, palladium, Parkinson Disease	Altered Intercellular Communication	Among the pathogenic processes contributing to dopaminergic neuron (DN) death in Parkinson disease (PD), evidence points to non-cell-autonomous mechanisms, particularly chronic inflammation mounted by activated microglia.	21467220
palladium	Altered Intercellular Communication	Together, our data indicate that GR is important in curtailing microglial reactivity, and its deregulation in PD could lead to sustained inflammation-mediated DN injury.	21467220
Pancreatic carcinoma	Altered Intercellular Communication	Inflammation-related gene variants as risk factors for pancreatic cancer.	21467233
Inflammation, Pancreatic carcinoma	Altered Intercellular Communication	Recent reports support an association between chronic inflammation and progression to pancreatic cancer (PC).	21467233
Inflammation, ovarian neoplasm	Altered Intercellular Communication	Circulating inflammation markers and risk of epithelial ovarian cancer.	21467242
Inflammation, ovarian neoplasm	Altered Intercellular Communication	Factors contributing to chronic inflammation appear to be associated with increased risk of ovarian cancer.	21467242
Takotsubo Cardiomyopathy, Hyponatremia	Altered Intercellular Communication	Takotsubo cardiomyopathy in a patient with severe hyponatremia associated with syndrome of inappropriate antidiuretic hormone.	21467706
diabetic	Altered Intercellular Communication	Results indicated that the fibrin network in all diabetic patients had thickened masses of thin, minor fibres over the major fibres, a profile typical of an inflammatory condition.	21467917
Unknown (origin) (qualifier value), Inflammation	Altered Intercellular Communication	Xanthogranulomatous inflammation (XGI) is a rare, idiopathic process in which lipid-laden histiocytes are deposited at various locations in the body.	21468270
CLU protein, human, Inflammation	Altered Intercellular Communication	Our results show that CLI is strongly correlated to inflammation, indicating a strong potential for proteomics analysis in the diagnosis of CLI.	21468429
Germinoma, Inflammation	Altered Intercellular Communication	The granulomatous inflammation occurring around germinomas can cause histological diagnostic difficulty.	21469434
Inflammation, Pain Distress Question	Altered Intercellular Communication	Dietary interventions involving antioxidants are of interest for reducing inflammation, improving joint motion, and altering pain perception.	21470042
Inflammation, Prostate carcinoma, Structure of posterior cerebral artery	Altered Intercellular Communication	The origin of chronic inflammation preceding the development of prostate cancer (PCa) remains unknown.	21471611
glycation, Inflammation, Overactive	Altered Intercellular Communication	The distribution and expression of cannabinoid receptors 1 (CNR1) and 2 (CNR2) in combination with inflammatory cytokines and RAGE (receptor of advanced glycation end products), which is also overactive in these diseases, in dependency of the extent of inflammation and alteration of the colon barrier is still unclear and needs to be elucidated.	21472688
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	We showed that cannabinoid receptors are expressed differentially in inflammatory bowel disease and that the expression seems to be influenced by the underlying disease and by localized inflammation.	21472688
Inflammation, Pulmonary function tests	Altered Intercellular Communication	The patient expressed marked eosinophilic inflammation and marked deterioration of pulmonary function while in persistent contact with the causal agent.	21472745
Intraocular inflammation, Hypertrophy	Altered Intercellular Communication	USG, CT and NMR scans revealed the intraocular inflammation and inflammatory enlargement of both lacrimal glands.	21473083
Intraocular inflammation, Lacrimal gland structure	Altered Intercellular Communication	Within weeks the intraocular inflammation was under control and the resolution of lacrimal glands edema was noted.	21473083
Intraocular inflammation, Chronic Lymphocytic Leukemia	Altered Intercellular Communication	Chronic lymphocytic leukemia rarely masks as chronic intraocular inflammation, in a sporadic cases however it may herald the relapse of the disease.	21473083
Pharyngitis	Altered Intercellular Communication	Immunohistochemical and western blot method were used to determine the expression of human nuclear distribution C in 80 cases of NPC and 30 cases of chronic inflammation of nasopharyngeal mucosa.	21473139
Pharyngitis	Altered Intercellular Communication	The positive expression rate of human nuclear distribution C in NPC was 83.75%, which was higher than that in chronic inflammation of nasopharyngeal mucosa 23.33% (P < 0.05).	21473139
Inflammation, Refractory anemias, Degenerative polyarthritis, Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	To evaluate the applicability of a lentiviral (LV) serum amyloid A3 (Saa3)-promoter luciferase (Luc) reporter for assessing inflammation in experimental arthritis, synovial fibroblasts (SF) from osteoarthritis (OA) and rheumatoid arthritis (RA) patients.	21474483
Arthritis, Streptococcus, Exacerbation of cGVHD	Altered Intercellular Communication	In mice, synovium was transduced in vivo by cholesterol optimised LV, and two flares of acute joint inflammation were induced by injection of streptococcal cell wall (SCW) material into the knee-joint cavity.	21474483
Inflammation	Altered Intercellular Communication	The time course of synovial inflammation was assessed using ex vivo luciferase assays, and histology.	21474483
Inflammation, Synovitis	Altered Intercellular Communication	The Saa3-promoter activities during acute inflammation correlated with Tc uptake measurements but were more sensitive and able to respond to the ongoing synovitis in the chronic phase of SCW arthritis.	21474483
Hyperglycemia, Inflammation, Brain Injuries, Cerebral Hemorrhage	Altered Intercellular Communication	Hyperglycemia and inflammation are involved in the progression of spontaneous intracerebral hemorrhage (sICH)-induced brain injury, but their role in predicting clinical outcome is not clear.	21474813
Inflammation, Atherosclerosis	Altered Intercellular Communication	Role of interleukin 17 in inflammation, atherosclerosis, and vascular function in apolipoprotein e-deficient mice.	21474820
Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	IL17 contributes to vascular and systemic inflammation in experimental atherosclerosis but does not alter plaque burden.	21474820
Inflammation	Altered Intercellular Communication	Low signals around the stent struts and tubular structure in the deep layer were also detected, suggesting the existence of inflammation and neovascularization, respectively.	21474860
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	This reflects the importance of inflammation in cancer survival.	21476028
Coronary Aneurysm, Inflammation	Altered Intercellular Communication	Electrocardiogram and physical examination were normal without any clinical signs of inflammation, but computed tomography (CT) scan and cardiac magnetic resonance imaging (MRI) revealed a giant (>50mm) coronary aneurysm.	21478051
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	The nasal polyp (NP) seems to represent the end-stage of longstanding inflammation in patients with chronic rhinosinusitis.	21478105
Airway structure	Altered Intercellular Communication	Asthma is characterised by chronic airway inflammation and remodelling, which can be (partially) suppressed by inhaled corticosteroids (ICSs).	21478212
Inflammation, Dermatitis	Altered Intercellular Communication	Here, we present 2 patients treated with imiquimod, whose biopsies showed interface dermatitis of the epidermis and the adnexae with prominent periadnexal and perivascular lymphocytic inflammation.	21478730
Colorectal Carcinoma	Altered Intercellular Communication	Our data suggest the importance of CYP19A1 in the development of colon and rectal cancer and that estrogen may influence risk through an inflammation-related mechanism.	21479914
Ischemia, Inflammation, Corneal edema	Altered Intercellular Communication	1 / 5 showed an anterior ischaemia with corneal oedema, anterior chamber inflammation and pupillotonia, but without involvement of the fundus.	21480161
Inflammation, Neoplasms	Altered Intercellular Communication	Although pretherapeutic radiological examination is a very useful technique for the evaluation of tumor invasion into specific laryngeal subsites, the pretherapeutic radiologic staging can be challenging when distinguishing tumor from peritumoral inflammation.	21480760
Inflammation, Acute Coronary Syndrome, Atherosclerosis, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation plays an important role in the pathogenesis of atherosclerosis and acute coronary syndromes (ACS).	21481602
Inflammation, Pancreatitis, Pancreatic Ductal Adenocarcinoma	Altered Intercellular Communication	Chronic pancreatitis is a well-known risk factor for pancreatic ductal adenocarcinoma (PDA) development in humans, and inflammation promotes PDA initiation and progression in mouse models of the disease.	21481787
Orbital Pseudotumor	Altered Intercellular Communication	Orbital inflammation with IgG4-positive plasma cells: manifestation of IgG4 systemic disease.	21482868
Inflammation, Giant Cell Arteritis	Altered Intercellular Communication	An ipsilateral temporal artery biopsy revealed inflammation that was mistakenly identified as giant cell arteritis.	21482932
Inflammation	Altered Intercellular Communication	Skeletal muscle aging is associated with increased inflammation and oxidative stress, a decrease in the ability to rebuild muscle after injury and in response to exercise.	21483036
Infiltration, Breast Carcinoma	Altered Intercellular Communication	The associations between CLEVER-1 expression on endothelial vessels and macrophage/leukocyte infiltration is suggestive of its regulation by inflammatory conditions in breast cancer, most likely by macrophage-associated cytokines.	21483103
Inflammation, atherosclerotic	Altered Intercellular Communication	Inflammation and biomechanical factors have been associated with the development of vulnerable atherosclerotic plaques.	21483158
Inflammation, Dental Plaque	Altered Intercellular Communication	All patients had plaque inflammation as shown by intraplaque accumulation of ultrasmall super paramagnetic particles of iron oxide on magnetic resonance imaging at baseline.	21483158
Inflammation, Cerebrovascular Circulation, Coronary heart disease	Altered Intercellular Communication	Therefore, we deduced that inflammation, from the histological point of view, is more correlated with cerebral circulation disorders than with coronary disease.	21483163
Communicable Diseases, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	Our data also indicate that, at least in this model, inflammation can predispose to retroviral infection and cancer.	21483485
Disease	Altered Intercellular Communication	Immune and inflammation-associated gene expression, in contrast, was more variable between models as compared to the human disease.	21483750
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterised by irreversible airflow obstruction, neutrophilic airway inflammation and chronic bacterial colonisation, however the role of the innate immune response in the pathogenesis of COPD remains unclear.	21483784
Malaria, Falciparum, Inflammation, Parasitemia	Altered Intercellular Communication	However, the reproducibility of those models is limited, with only a proportion of animals supporting longstanding parasitemia, due to strong inflammation induced by P. falciparum.	21483851
Malaria, Falciparum, Inflammation	Altered Intercellular Communication	We demonstrate here the role of aging, of inosine and of the IL-2 receptor g mutation in controlling P. falciparum induced inflammation.	21483851
Granulomatous inflammation, Infiltration	Altered Intercellular Communication	Contribution of T cell-mediated immunity is suggested by the presence of granulomatous inflammation and T cell infiltrates in different tissues.	21484763
Inflammation, Hyperlipidemia	Altered Intercellular Communication	BSS would further accelerate the chronic inflammation process of hyperlipidemia.	21485068
Hepatic inflammation, Ascites	Altered Intercellular Communication	Further analysis showed that internal accumulation of dampness-heat syndrome was characterized by obvious hepatic inflammation, poor synthesis function and more ascites.	21486549
Ascites	Altered Intercellular Communication	Liver-kidney yin deficiency syndrome was characterized by low-level hepatic inflammation, poor synthesis function and more ascites.	21486549
Avitaminosis, Hepatic inflammation, Ascites, Depression, CTCAE, Blood Stasis, Traumatic injury	Altered Intercellular Communication	Internal accumulation of blood stasis-heat syndrome was characterized by low-level hepatic inflammation, poorer synthesis function, ascites and splenomegalia, and liver depression and spleen deficiency syndrome was characterized by slight hepatic inflammation, synthesis function injury, decreased internal portal vein diameter and less ascites.	21486549
Inflammation, Deposition, Endothelial dysfunction, Obesity	Altered Intercellular Communication	Obesity is associated with endothelial dysfunction and increased inflammation as well as with expansion of the capillary bed in regional adipose deposits, and a balance between these factors is involved in angiogenesis.	21486700
Inflammation	Altered Intercellular Communication	Osteopontin (OPN) is a proinflammatory cytokine involved in regulating immune processes and mediating chronic inflammation.	21486700
Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Portal inflammation	Altered Intercellular Communication	Bile ductules positive for CK19 were increased along with the progression of staging and fibrosis of NAFLD, and the increased bile ductules were associated with portal inflammation and fibrosis.	21486894
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Such senescent bile ductules frequently express chemotactic protein, CCL2 (MCP-1), which may be responsible for chemoattraction of activated HSC around the bile ductules in portal and septal fibrosis and for portal inflammation.	21486894
Inflammation, Crohn Disease, melanoma, Lymphangiectasis, Malabsorption Syndrome, Enteritis	Altered Intercellular Communication	SBE diagnosed Crohn's disease in four patients, malabsorption syndromes in two, lymphangiectasia in two, eosinophilic enteritis in one, melanoma in one, and nonspecific inflammation in eight.	21487872
Manufactured sign, Precocious Puberty	Altered Intercellular Communication	Hormonal signs (precocious puberty, telarca, menarche) were common in younger patients and led to an early diagnosis.	21488154
Tissue damage, Inflammation, Thrombus, Thrombophilia	Altered Intercellular Communication	This hypercoagulability may contribute to inflammation, tissue damage and, possibly, thrombotic risk.	21488867
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Impact of biomarkers of inflammation and extracellular matrix turnover on the outcome of atrial fibrillation ablation: importance of matrix metalloproteinase-2 as a predictor of atrial fibrillation recurrence.	21489023
Myocardial fibrosis, Atrial Fibrillation, Inflammation	Altered Intercellular Communication	AF is associated with inflammation and subsequent myocardial fibrosis.	21489023
Inflammation	Altered Intercellular Communication	Gastric cardiac-type mucosa with acute and chronic inflammation was documented on biopsy.	21489041
Inflammation	Altered Intercellular Communication	Thrombomodulin, which is expressed solely on monocytes, along with tissue factor (TF), takes part in coagulation and inflammation.	21489300
Inflammation	Altered Intercellular Communication	ISR lesions after drug-eluting stenting showed persistent signs of delayed or incomplete wound healing and relapsed inflammation, compared with BMS.	21489821
Inflammation, Spinal Diseases	Altered Intercellular Communication	Human neuropathological and animal model evidence supporting a role for Fas-mediated apoptosis and inflammation in cervical spondylotic myelopathy.	21490053
Inflammation, Traumatic, Spinal Cord Injuries, Spinal Diseases	Altered Intercellular Communication	Based on animal models of cervical spondylotic myelopathy and traumatic spinal cord injury, we hypothesized that Fas-mediated apoptosis and inflammation may play an important role in the pathobiology of human cervical spondylotic myelopathy.	21490053
Inflammation, Spinal Diseases	Altered Intercellular Communication	Our data demonstrate, for the first time in humans, the potential contribution of Fas-mediated cell death and inflammation to the pathobiology of cervical spondylotic myelopathy.	21490053
Inflammation, Stomach Neoplasms	Altered Intercellular Communication	Loss of TFF1 is associated with activation of NF-kB-mediated inflammation and gastric neoplasia in mice and humans.	21490402
Inflammation, Endothelial dysfunction, Autoimmune thyroiditis, Hypothyroidism	Altered Intercellular Communication	Endothelial dysfunction and low grade chronic inflammation in subclinical hypothyroidism due to autoimmune thyroiditis.	21490407
Inflammation, Endothelial dysfunction, Atherosclerosis, Hypothyroidism	Altered Intercellular Communication	Our study aims to investigate the presence of the well known preceding clinical situations of atherosclerosis like endothelial dysfunction and inflammation in subclinical hypothyroidism.	21490407
Saint Helena Islands, Inflammation, Endothelial dysfunction, Autoimmune thyroiditis	Altered Intercellular Communication	Our findings suggest that there is endothelial dysfunction and low grade chronic inflammation in SH due to autoimmune thyroiditis.	21490407
Inflammation	Altered Intercellular Communication	According to our results low grade chronic inflammation may be one of these factors.	21490407
Ischemia, Inflammation, Vascular System Injuries	Altered Intercellular Communication	In models of acute ischaemia, erythropoietin (EPO) administration has been found to attenuate vascular injury largely through reduced apoptosis, suppressed inflammation and increased nitric oxide availability.	21492156
Inflammation, Chronic pain	Altered Intercellular Communication	Patients have been given multiple courses of antibiotics even in the absence of identifiable organisms, anti-inflammatory drugs in the absence of proven inflammation, and narcotic analgesics in an attempt to control chronic pain.	21492375
Autoimmune Diseases, Lupus Erythematosus, Acute and chronic inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Systemic lupus erythematosus (SLE) is an autoimmune disease with chronic or episodic inflammation in many different organ systems, activation of leukocytes and production of pro-inflammatory cytokines.	21492422
Inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Patients with SLE had increased cell surface S100A8/A9, which could be important in amplification and persistence of inflammation.	21492422
Inflammation, Cerebral Aneurysm, Aneurysm	Altered Intercellular Communication	Polyglycolic-polylactic acid (PGLA) coils induce inflammation within a cerebral aneurysm, which in turn is hypothesized to decrease aneurysm recurrence.	21492633
Arterial Stiffness, Inflammation, HIV Infections	Altered Intercellular Communication	HIV disease is associated with increased arterial stiffness, which may be related to inflammation provoked by HIV-related immune perturbation.	21492857
Inflammation	Altered Intercellular Communication	Cryopyrin-associated periodic syndromes (CAPS) represent a spectrum of CIAS1 gene-mediated autoinflammatory diseases characterized by recurrent systemic inflammation.	21493283
Glomerulitis (disorder), Arteriosclerosis, Interstitial inflammation	Altered Intercellular Communication	Accelerated arteriosclerosis was significantly associated with peritubular capillary leukocytic infiltration, glomerulitis, subclinical antibody-mediated rejection, and interstitial inflammation.	21493773
Asthma, Myositis	Altered Intercellular Communication	Severe asthma is characterized by a dramatic increase in smooth muscle and airway inflammation.	21493783
Inflammation, Asthma	Altered Intercellular Communication	Taken together, these results highlight the ERK1/ERK2 MAPK cascade as a novel and attractive target in severe asthma because the activation of this pathway is insensitive to the action of glucocorticoids and is involved in neutrophil recruitment, contributing the to inflammation seen in the disease.	21493783
Hemangioma, Cavernous, Inflammation, Congenital arteriovenous malformation	Altered Intercellular Communication	Cavernomas and arteriovenous malformations are also sites of active inflammation.	21493906
Inflammation, Septic Shock	Altered Intercellular Communication	Circulating microparticles from septic shock patients exert differential tissue expression of enzymes related to inflammation and oxidative stress.	21494101
Leukoencephalopathy, Inflammation, Encephalitis	Altered Intercellular Communication	To control for the possibility that inflammation owing to other etiologies could result in EBV-positive cell accumulation, 11 brain biopsies of encephalitis and 4 brain biopsies of progressive multifocal leukoencephalopathy were also studied.	21494180
Inflammation, Discitis	Altered Intercellular Communication	Radical surgical debridement and appropriate antibiotic provide a reliable approach to achieve complete healing of the inflammation in cervical spondylodiscitis.	21494200
Takayasu Arteritis	Altered Intercellular Communication	Takayasu arteritis is an inflammatory condition that involves the large cardiac vessels, predominantly the aorta and its main branches.	21494533
Airway structure	Altered Intercellular Communication	Increased central sympathetic nerve activity induced by local airway inflammation may be one possible mechanism.	21494635
Airway structure	Altered Intercellular Communication	However, we can not exclude that chronic airway inflammation may contribute to sympathetic activation.	21494635
Arthralgia, Bothered by Vomiting	Altered Intercellular Communication	Three mild and transient adverse events (upper respiratory tract inflammation, arthralgia, and vomiting) were reported in the study.	21494765
Inflammation, Traumatic injury	Altered Intercellular Communication	At the same time, the present case demonstrated that it is very difficult to understand and predict changes in the inflammation process associated with children's facial trauma.	21496202
vascular inflammations, Fever	Altered Intercellular Communication	Kawasaki disease is an acute febrile disease of unknown etiology, characterized by systemic vascular inflammation involving the small and medium sized arteries, with a predilection for the coronary arteries.	21496328
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Hepatic BAMBI is reduced in rodent models of liver inflammation and fibrosis.	21496456
Cyst, Inflammation	Altered Intercellular Communication	The SOTLPs appear to originate from the epithelial lining of the cyst and do not appear to be directly associated with inflammation.	21496660
Amyloidosis	Altered Intercellular Communication	Recurrent AA amyloidosis in a kidney transplant is rare, especially when the underlying inflammatory condition is controlled.	21496981
Duodenal Perforation, CTCAE, Inflammation	Altered Intercellular Communication	We managed a 31-y-old bedridden case with punched out duodenal perforation without inflammation, from which the tip of the PEG tube protruded.	21497055
TNF protein, human, Tumor necrosis, Becquerel, Lip and Oral Cavity Carcinoma	Altered Intercellular Communication	Betel quid (BQ) components induce the secretion of tumour necrosis factor-alpha (TNF-a) in oral keratinocytes, which promotes oral mucosal inflammation and oral cancer.	21497332
Inflammation, Chronic sinusitis, Craniosynostosis, Chronic disease	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) is a heterogeneous chronic disease characterized by local inflammation of the sinonasal tissues.	21497884
Inflammation	Altered Intercellular Communication	Overproduction of CCL23 in NPs might contribute to the pathogenesis of eosinophilic CRSwNP through the recruitment of CCR1(+) inflammatory cells, including monocytes and macrophages, and the amplification of local inflammation.	21497884
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	We also propose that the post-translational modifications identified in CYP27A1 exemplify a general mechanism whereby oxidative stress and inflammation deleteriously affect protein function, contributing, for example, to cholesterol-rich lesions associated with age-related macular degeneration and cardiovascular disease.	21498512
Inflammation, Thrombosis	Altered Intercellular Communication	Inflammation might contribute to the development of stent thrombosis (ST).	21498913
Inflammation	Altered Intercellular Communication	Uric acid (UA) is a cardiovascular risk marker associated with oxidative stress and inflammation.	21498925
Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Recently, atrial fibrillation (AF) has been associated with inflammation and oxidative stress.	21498925
Cardiomyopathies, Congenital heart disease, Congestive heart failure, Diabetes Mellitus, Coronary Artery Disease, Thyroid dysfunction, Respiration Disorders, Kidney Failure, Heart valve disease	Altered Intercellular Communication	We excluded subjects with coronary artery disease, congestive heart failure, diabetes, valvular heart disease, congenital heart disease, cardiomyopathy, renal failure, inflammatory conditions, thyroid dysfunction, respiratory diseases, and those who were taking drugs that affect UA metabolism (apart from diuretics).	21498925
Malnutrition	Altered Intercellular Communication	In elderly MHD patients, it was possible to achieve improvements in both malnutrition and chronic inflammatory conditions with AN69.	21499075
Tissue damage, Inflammation	Altered Intercellular Communication	No tissue damage, inflammation, lesions, and QDs deposition were found in histology and TEM images of the anti-HER2ab-QDs treated group.	21499435
Inflammation, Obstructive nephropathy due to prostatic hypertrophy	Altered Intercellular Communication	In this investigation, we study the relation between chronic inflammation of the tonsils, clinical features, and the presence of biofilms in the crypts in patients presenting with obstructive hypertrophy and recurrent upper airway pathology.	21499955
Inflammation, Thrombus	Altered Intercellular Communication	Circulating tissue factor (TF) is associated with inflammation and may contribute to thrombotic events.	21500176
Giant cell sarcoma, Hodgkin Disease	Altered Intercellular Communication	FNA, core needle biopsy, and even small incisional biopsies may result in misdiagnosis of IMTDE as pleomorphic sarcoma, an inflammatory condition or even Hodgkin's disease.	21500374
Inflammation, Fatty degeneration	Altered Intercellular Communication	Inflammation is one mechanism that may link myosteatosis with increased T2DM risk, but studies examining the relationship between inflammation and myosteatosis are lacking.	21501070
Heredity, Inflammation	Altered Intercellular Communication	Our findings suggest that heredity may play a significant role in the determination of several markers of inflammation in African ancestry individuals.	21501070
Inflammation, Demyelination, Axonal loss, Degenerative disorder, Failure (biologic function)	Altered Intercellular Communication	Multiple sclerosis (MS) is a chronic progressive degenerative disorder of the central nervous system, characterized by inflammation, demyelination, ultimate failure of remyelination and axonal loss.	21501208
Inflammation, Carcinogenesis	Altered Intercellular Communication	Chronic inflammation is related to oxidative stress and is still believed to be the cause of carcinogenesis.	21501233
Cyst, Inflammation	Altered Intercellular Communication	Furthermore, cyst development is accompanied by chronic inflammation.	21501233
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Neutrophils in colonic mucosal tissue of patients with ulcerative colitis were the main cellular source of PTX3 protein, the expression of which is correlated well with the histological grades of inflammation.	21501295
Inflammation	Altered Intercellular Communication	Immunohistochemistry revealed that type IV collagen around capillaries in the area of the PCH without inflammation disappeared in the area with inflammation.	21501297
Inflammation	Altered Intercellular Communication	Obesity-associated macrophage infiltration into adipose tissue is responsible for both local and systemic inflammation.	21501656
Diabetes Mellitus, Non-Insulin-Dependent, Carcinogenesis, Hepatitis	Altered Intercellular Communication	Type 2 diabetes (T2DM) is associated with liver inflammation and carcinogenesis.	21501980
Inflammation, Secondary malignant neoplasm of liver, Pregnancy Complications, Infectious	Altered Intercellular Communication	Preoperative systemic inflammation and infectious complications after resection of colorectal liver metastases.	21502458
Inflammation, Secondary malignant neoplasm of liver, Pregnancy Complications, Infectious	Altered Intercellular Communication	To examine the association of postoperative infectious complications with preoperative systemic inflammation and survival in patients undergoing resection of colorectal liver metastases.	21502458
Chlamydia trachomatis, Upper Respiratory Infections	Altered Intercellular Communication	Nevertheless, chlamydial agents (C. trachomatis in infants, C. pneumoniae in pre-school children) should be taken into consideration in a differential diagnosis of respiratory tract inflammation.	21503738
Inflammation, Data types - Address, Nerve Degeneration	Altered Intercellular Communication	Among the pathogenic mechanisms in AD, chronic systemic inflammation is described and characterized by massive production of proinflammatory cytokines by peripheral blood mononuclear cells (PBMCs), which may contribute to an altered immune response and exacerbation of neurodegeneration.	21504114
Airway structure, Asthma, Bronchial Hyperreactivity	Altered Intercellular Communication	Comparison of bronchial hyperresponsiveness to methacholine and adenosine and airway inflammation markers in patients with suspected asthma.	21504347
Bronchitis	Altered Intercellular Communication	Indirect stimuli provide a better reflection of bronchial inflammation.	21504347
Metatarsophalangeal joint structure	Altered Intercellular Communication	US finding indicative of metatarsophalangeal joint inflammation were obtained in 77 (76.2%) patients, while only 34 (33.7%) patients were positive to the clinical examination.	21504659
Chronic dacryocystitis, Chronic infectious disease, Inflammation	Altered Intercellular Communication	Chronic dacryocystitis results in chronic infection and inflammation of the lacrimal sac.	21505526
Cataract, Pain Distress Question, Acute inflammation, Tissue damage	Altered Intercellular Communication	Small incisions in cataract surgery have shown to reduce tissue damage, postoperative inflammation and pain.	21505539
Inflammation	Altered Intercellular Communication	No cases of postoperative hypotony and increased inflammation were observed.	21505539
ARCN1 gene, Inflammation, Atherosclerosis	Altered Intercellular Communication	Although systemic inflammation plays the leading role in atherothrombotic processes, platelet activation and increased coagulation together with oxidative stress can significantly exacerbate atherosclerosis in COPD patients.	21506665
Inflammation	Altered Intercellular Communication	The presence of systemic inflammation was clearly proved by the increase in classical inflammatory markers (CRP, WBC and segmented neutrophil count).	21506665
Presenile dementia, Inflammation	Altered Intercellular Communication	Mean plaques scores and extent of gingival inflammation were higher for residents in the DD and D subgroups and resident with dementia.	21507056
Gingivitis, Dental Plaque	Altered Intercellular Communication	Residents assisted with brushing had higher mean plaque score and more moderate gingival inflammation.	21507056
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Patients with end-stage renal disease are prone to inflammation and inflammation is related to erythropoietin-stimulating agent hyporesponsiveness and mortality in this population.	21507195
Inflammation, Anemia	Altered Intercellular Communication	In this retrospective analysis, we determined whether the use of statins improves inflammation and inflammation-related anemia in a cohort of hemodialysis patients.	21507195
Carcinoma of larynx, Inflammation, Mutagenicity Tests	Altered Intercellular Communication	Bile acids in reflux material accumulate in the laryngeal tissue in laryngeal carcinoma patients; therefore, bile acids should be considered a carcinogenic factor in the etiology of laryngeal carcinoma because of their mutagenicity due to DNA breaking, as they cause chronic inflammation due to intracellular accumulation.	21508656
Inflammation, Chronic Obstructive Airway Disease, Chronic Kidney Diseases	Altered Intercellular Communication	There is some evidence that chronic obstructive pulmonary disease and chronic kidney disease (CKD) may be related, perhaps through systemic inflammation, which is common to both.	21509480
Inflammation	Altered Intercellular Communication	Analysis of synovial fluid in knee joint of osteoarthritis:5 proteome patterns of joint inflammation based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.	21509578
Inflammation, Varicose, Edema, Pain Distress Question	Altered Intercellular Communication	The VCSS of varicose, edema, pigmentation, and inflammation were significantly reduced after both EVL and CHIVA; however, patients treated by EVL had significantly more pain postoperatively than those treated by CHIVA (p=0.003).	21509638
Inflammation, Retinitis Pigmentosa, Chondritis of pinna, polychondritis	Altered Intercellular Communication	Bilateral auricularis and nasal root inflammation, with auricular perichondritis positive for anti-type II collagen (CII) antibody, led to a diagnosis of relapsing polychondritis (RP).	21509650
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	The state of lipid metabolism, parameters of the oxidant system and inflammation markers were determined in healthy people (n = 30) and patients with hypertension (n = 132) of 60-74 years old.	21510081
Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Inflammation, neovascularization and intra-plaque hemorrhage are associated with increased reparative collagen content: implication for plaque progression in diabetic atherosclerosis.	21511672
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Sustained inflammation may stimulate a reparative process increasing early reparative type III collagen synthesis, promoting atherosclerotic plaque progression.	21511672
Inflammation, Demographics Domain, Diabetes Mellitus	Altered Intercellular Communication	We evaluated inflammation, neovascularization, intra-plaque hemorrhage (IPH), and collagen deposition in human aortic atherosclerotic plaques from patients with and without diabetes mellitus (DM).	21511672
Inflammation, Fibrous	Altered Intercellular Communication	In non-DM plaques, 27%, 40%, and 33% had mild, moderate and severe inflammation in the fibrous cap and shoulder compared with 2%, 30% and 68% in DM plaques (p < 0.001).	21511672
Inflammation	Altered Intercellular Communication	In conclusion, our study suggests that enhanced type III collagen deposition was associated with inflammation, neovascularization and IPH, and may be a contributing factor in DM plaque progression.	21511672
Inflammation, Traumatic injury, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Cardiac MRI (CMRI) provides a comprehensive assessment of myocardial function, inflammation and injury in a single examination and has shown value in the diagnosis of myocarditis.	21511746
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Baseline levels of plasma biomarkers of inflammation and fibrosis significantly correlated with baseline eGFR but did not predict response to therapy.	21511828
Cessation of life, Dyslipidemias, atherosclerotic	Altered Intercellular Communication	In this hemodialysis cohort, dyslipidemia was associated with increased risk of incident atherosclerotic CVD, and protein energy wasting/inflammation with increased risk of death after CVD events.	21511840
Inflammation	Altered Intercellular Communication	[Specific features of the development of chronic inflammation in the maxillary sinus].	21512475
Cholangiolitis, Inflammation	Altered Intercellular Communication	Cholangiolitis, inflammation of the cholangioles, is difficult to diagnose by conventional imaging modalities.	21512668
Malignant tumor of colon, Inflammation, Mucinous, Mucinous Adenocarcinoma	Altered Intercellular Communication	To determine whether contrast-enhanced ultrasonography (CEUS) can be used to discriminate between colon cancer and acute inflammation, and between mucinous and non-mucinous carcinoma.	21512723
Malignant tumor of colon, Inflammation	Altered Intercellular Communication	CEUS (with perflubutane microbubbles) was performed in two study groups: colon cancer (n = 34) and acute inflammation (n = 14).	21512723
Malignant tumor of colon, Inflammation	Altered Intercellular Communication	Differentiation between colon cancer and acute inflammation is possible with CEUS.	21512723
Malignant tumor of colon	Altered Intercellular Communication	The vascular structure was irregular in 76.5% of colon cancers but only 28.6% of acute inflammations (P < 0.01).	21512723
Malignant tumor of colon	Altered Intercellular Communication	Both abnormalities were found in 58.8% of colon cancers but in none of the acute inflammations.	21512723
Mycobacterium Infections, Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Twenty-one patients with mycobacterial infection had available biopsy or surgical specimens for histopathologic examination and 16 (76.2%) specimens had pathologic features (granulomatous inflammation, caseating necrosis, or acid-fast bacilli) consistent with mycobacterial infection.	21513844
Dermatitis, Atopic, Superinfection, Data types - Address, Dermatitis	Altered Intercellular Communication	Staphylococcus aureus superinfections occur in more than 90% of patients with atopic dermatitis (AD) and aggravate skin inflammation.	21513970
Tissue damage, Dermatitis	Altered Intercellular Communication	S aureus toxins lead to tissue damage and augment T-cell-mediated skin inflammation by a superantigen effect.	21513970
Data types - Address	Altered Intercellular Communication	Evidence is provided that specific humoral and cellular immune responses to S aureus antigens dependent on antigen presentation represent a novel mechanism for S aureus-induced skin inflammation in AD.	21513970
Inflammation, Dyslipidemias, atherosclerotic, Obesity	Altered Intercellular Communication	Obesity related dyslipidemia, chronic inflammation and oxidative stress were associated with atherosclerotic sequels.	21515245
Inflammation	Altered Intercellular Communication	The accumulation of senescent stromal cells in aging tissue changes the local microenvironment from normal to a state similar to chronic inflammation.	21515933
Gingivitis, Hemorrhage, Dental Plaque	Altered Intercellular Communication	Clinical assessments of dental implants and contralateral natural teeth included dental plaque, gingival inflammation, and bleeding on probing.	21516280
Communicable Diseases, Inflammation, Gastritis	Altered Intercellular Communication	The aim of the work was to study the relationship between structural changes in gastric mucosa affected by atrophic gastritis and inflammation associated with Hp infection.	21516763
Inflammation, Pathology	Altered Intercellular Communication	Endoscopic examination and NBI-visualization were used to assess distribution and severity of inflammation in 500 patients with different gastric pathologies.	21516763
Inflammation, Atrophic	Altered Intercellular Communication	Mucosal changes characteristic of atrophy were only rarely accompanied by marked inflammation (14.8%) and were either mild (21%) or moderately severe (64.2%).	21516763
Gastric mucosa, Inflammation, Gastritis, Atrophic	Altered Intercellular Communication	It suggests that atrophy of gastric mucosa should be regarded as independent condition while the term atrophic gastritis should be used only in case of association between atrophy and inflammation confirmed by microscopic studies.	21516763
Inflammation	Altered Intercellular Communication	Endoscopic ligation of the esophageal veins did not change the rate of EM inflammation detection.	21516841
Inflammation	Altered Intercellular Communication	This is evidence that IL-6 in the urine had a local origin (intrarenal), reflecting activity of immune inflammation in the kidney.	21516850
Postprandial Period, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Effects of mealtime insulin aspart and bedtime NPH insulin on postprandial inflammation and endothelial cell function in patients with type 2 diabetes.	21518259
Inflammation, Endothelial dysfunction, Hyperglycemia	Altered Intercellular Communication	We suggested that rapid-acting insulin has a beneficial postprandial effect on endothelial dysfunction and inflammation compared with intermediate-acting insulin because of its ability to lower postprandial hyperglycaemia.	21518259
Lymphoproliferative Disorders	Altered Intercellular Communication	Our data suggests that PL may represent an inflammatory condition induced by various triggering agents, such as HHV-8, rather than a lymphoproliferative disorder.	21518386
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Serum hs-CRP levels could predict the incidence of diabetes, indicating that inflammation might have great importance in the onset of diabetes.	21518530
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Inflammation may be involved in prostate cancer development and progression.	21518693
Inflammation, Drug-induced, leukemia, Neoplasms	Altered Intercellular Communication	Enlargement can be of many types depending on etiologic factors like inflammation, drug-induced effects, neoplasm, hormonal imbalance, and systemic involvement (leukemia, etc).	21519587
Inflammation, Drug-induced, leukemia, Neoplasms	Altered Intercellular Communication	Enlargement can be of many types depending on etiologic factors like inflammation, drug-induced effects, neoplasm, hormonal imbalance, and systemic involvement (leukemia, etc).	21519587
Inflammation, Dental caries, Osteopenia	Altered Intercellular Communication	Occasionally dental caries could compromise the interproximal contact point, leading to migration of the adjacent teeth with consequent retention of food, gingival inflammation, pocket formation, bone loss and dental mobility.	21519654
Inflammation	Altered Intercellular Communication	Visceral adipose tissue may fuel obesity-associated chronic inflammation and tumorigenesis.	21520028
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	T cells may be important in visceral adipose tissue in driving inflammation, but they have not yet been characterized in patients with cancer.	21520028
Inflammation	Altered Intercellular Communication	It may fuel chronic inflammation via T cell-mediated pathways.	21520028
Inflammation, Prostate carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Androgens and inflammation have been implicated in the etiology of several cancers, including prostate cancer.	21520164
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	High plasma retinol binding protein 4 (RBP4) is associated with systemic inflammation independently of low RBP4 adipose expression and is normalized by transplantation in nonobese, nondiabetic patients with chronic kidney disease.	21521262
Inflammation, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Potential involvement of plasma and adipose RBP4 in systemic inflammation in the absence of obesity and diabetes is unknown.	21521262
Renal Insufficiency, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation reduces survival in chronic kidney disease (CKD) [particularly in maintenance haemodialysis (MHD)], and plasma RBP4 may increase with renal dysfunction.	21521262
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We investigated (i) potential associations between RBP4 and inflammation in CKD and (ii) the role of adipose tissue in this putative interaction.	21521262
Inflammation, Obesity, Chronic Kidney Diseases, Diabetes Mellitus	Altered Intercellular Communication	High plasma RBP4 and inflammation are clustered in CKD in the absence of obesity and diabetes and are normalized by transplantation.	21521262
Inflammation	Altered Intercellular Communication	Cardiopulmonary bypass (CPB) and cardiac surgery cause an inflammatory response, as measurable by an increase in the concentration of C-reactive protein (CRP), a nonspecific inflammation marker.	21521673
Inflammation, Abnormality of mitochondrial metabolism, Hypoxia, Neoplasms	Altered Intercellular Communication	Gene set enrichment analysis (GSEA) revealed "stemness," inflammation, DNA damage, aging, oxidative stress, hypoxia, autophagy and mitochondrial dysfunction in the tumor stroma of patients lacking stromal Cav-1.	21521946
Granulomatous inflammation, Malignant Neoplasms	Altered Intercellular Communication	Breast malignancy or granulomatous inflammation could not be excluded.	21522109
Granulomatous Cheilitis	Altered Intercellular Communication	Granulomatous cheilitis is a rare granulomatous inflammation of the lips of unknown origin; mainly young adults are affected.	21523519
Diverticulum, Hemorrhage, Intussusception, Perforation (observation)	Altered Intercellular Communication	The diverticulum complication generated: occlusion--43.7% (n = 15), inflammation--37.5% (n = 12), bleeding, two cases of diverticulum tumor, an intussusception case and a perforation case with unknown object.	21523959
Inflammation, Anemia	Altered Intercellular Communication	The main type of anemia present among women 18-49 years old was IDA (61% of anemia cases) while anemic women 50 years and over suffered mainly from anemia related to chronic inflammation (ACI) (42%).	21524361
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	These results suggest inflammation, as measured by hs-CRP level, is associated with carotid artery IMT among hypertensive adults rather than other traditional risk factors.	21524639
Inflammation	Altered Intercellular Communication	RHR was associated with markers of chronic low-grade inflammation.	21525123
Inflammation, Critical Illness	Altered Intercellular Communication	A comparison of zinc metabolism, inflammation, and disease severity in critically ill infected and noninfected adults early after intensive care unit admission.	21525204
Inflammation, Hyperglycemia	Altered Intercellular Communication	These data highlight the importance of diet composition in the treatment and prevention of inflammation and hyperglycemia.	21525252
Inflammation	Altered Intercellular Communication	These patients are on maintenance hemodialysis where they are exposed to dialysis fluid and dialysis membrane that generate an acute-phase response, which leads to inflammation, reflected in increased inflammatory markers like C-reactive protein (CRP) and interleukin-6 (IL-6).	21525578
Neoplasms	Altered Intercellular Communication	Recent evidence suggests that the chemokine axis of CXC chemokine ligand-12 and its receptor CXC chemokine receptor-4 (CXCL12/CXCR4) is highly expressed in gynecological tumors and the axis of CXC chemokine ligand-16 and CXC chemokine receptor-6 (CXCL16/CXCR6) is overexpressed in inflammation-associated tumors.	21527066
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The fixed combination of pioglitazone and metformin improves biomarkers of platelet function and chronic inflammation in type 2 diabetes patients: results from the PIOfix study.	21527115
Inflammation, Sarcopenia, Malnutrition, Chronic disease	Altered Intercellular Communication	The causes of sarcopenia are multifactorial and can include disuse, altered endocrine function, chronic diseases, inflammation, insulin resistance, and nutritional deficiencies.	21527165
Inflammation, Edema	Altered Intercellular Communication	When comparing groups 1 and 2, there was no statistically significant difference in inflammation and edema.	21527192
Inflammation, Melanosis, Non-Malignant	Altered Intercellular Communication	We retrospectively reviewed all non-malignant colon mucosal biopsies between 2005 and 2007, reported as normal, chronic inflammation or melanosis coli in patients who were undergoing routine colonoscopy.	21528078
Inflammation	Altered Intercellular Communication	The sustained release of large quantities of autologous growth factors, cytokines, and other mediators found in PRP plus the favorable mononuclear cell profile of PRP may help us to stimulate wound healing and resolve chronic inflammation.	21528636
Inflammation, Ear Inflammation	Altered Intercellular Communication	The only adverse reactions were episodic inflammations of the upper and/or lower respiratory tract, but there was no otitis.	21528770
Inflammation, Carcinogenesis, Chronic disease	Altered Intercellular Communication	Oxidative stress and inflammation are constant features of many chronic diseases and complications, and have been linked to carcinogenesis.	21530094
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Although there is widespread interest in fractional exhaled nitric oxide (FeNO) as a non-invasive, time and cost effective biomarker for assessing airway inflammation in chronic obstructive pulmonary disease (COPD), its usefulness is still controversial.	21530214
Inflammation, Cardiac fibrosis, Hypertension, CTCAE	Altered Intercellular Communication	Hypertension causes cardiac fibrosis characterized by low-grade inflammation.	21530504
Airway structure, Asthma, Eosinophilic inflammation	Altered Intercellular Communication	Fractional exhaled nitric oxide (FeNO) measurement is an index of airway eosinophilic inflammation and is primarily employed to diagnose bronchial asthma and assess airway inflammation.	21530868
Inflammation, Dysplasia, Malignant neoplasm of gastrointestinal tract, Neoplasms	Altered Intercellular Communication	The frequency of HLTF methylation in high grade dysplasia and GCA tumor tissues was significantly higher than that in chronic inflammation tissues and was significantly associated with upper gastrointestinal cancers (UGIC) family history and protein and mRNA expression of the gene.	21531217
Inflammation, Dysplasia	Altered Intercellular Communication	HLTF methylation was not found in the plasma of patients with chronic inflammation and low grade dysplasia, while 4.0% (1/25) of patients with high grade dysplasia and 20.8% of (20/96) GCA patients were detected with hypermethylation of HLTF in the plasma.	21531217
Inflammation, Peritonitis	Altered Intercellular Communication	In univariate analysis, baseline PAD, peritonitis during follow-up, inflammation (C-reactive protein), serum uric acid, CaxP, and serum phosphate were all significantly associated with a greater-than-50% decrease in RRF during follow-up.	21532004
Inflammation, Infection of bloodstream, Critical Illness	Altered Intercellular Communication	Red cell distribution width is a robust predictor of the risk of all-cause patient mortality and bloodstream infection in the critically ill. Red cell distribution width is commonly measured, inexpensive, and widely available and may reflect overall inflammation, oxidative stress, or arterial underfilling in the critically ill.	21532476
Inflammation	Altered Intercellular Communication	Cytokines such as interleukin 10 (IL10) may play an important role in the process of inflammation.	21532858
Inflammation, Necrosis, Fibrosis Assessment, Metaplasia, Hyperplasia	Altered Intercellular Communication	Direct correlation was seen between tendon and bursal hyperplasia and time of the onset of symptoms; between tendon chondral metaplasia, fibrosis, bursal neoangiogenesis, inflammation, and patient age; between tendon neoangiogenesis, hyperplasia, necrosis, fibrosis, bursal necrosis, inflammation, and lesion size; on the contrary, tendon fibrosis, necrosis, and bursal tissue inflammation decrease as time passes from the onset of symptoms.	21533534
Inflammation	Altered Intercellular Communication	Tendon fibers disarray, neoangiogenesis, and inflammation decreases as the patient's age increases.	21533534
Inflammation	Altered Intercellular Communication	Consequently, the patient recovered gradually from the inflammation and underwent CABG as scheduled 28 days later.	21533587
Tubercular	Altered Intercellular Communication	Unilateral obstruction of the foramen of Monro due to chronic tubercular ependymal inflammation was suspected and endoscopic septostomy was planned.	21534211
Inflammation, hepcidin, Anemia	Altered Intercellular Communication	IL6 and hepcidin levels did not differ significantly between AUE and control groups, indicating that inflammation or iron restriction is not central feature of anaemia in this group.	21535154
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	After additional adjustment for markers of inflammation and endothelial dysfunction, the association was attenuated (HR 1.50; 95% CI, 1.08-2.09).	21535251
Inflammation, MS gene, Nerve Degeneration	Altered Intercellular Communication	Literature includes evidence of initial predominance of inflammation and later development of neurodegeneration in the pathogenesis of multiple sclerosis (MS).	21535941
Immunologic Deficiency Syndromes, Inflammation	Altered Intercellular Communication	Inflammation in common variable immunodeficiency is associated with a distinct CD8(+) response to cytomegalovirus.	21536322
Inflammation	Altered Intercellular Communication	This complication necessitated a first exploratory and cleansing surgery, as well as a second surgery, which clarified the origin of the inflammation and made it possible to eliminate the wax remains.	21536361
Corneal Neovascularization	Altered Intercellular Communication	Similarly, in a model of inflammation-induced corneal neovascularization, young TSP-1-deficient mice develop exacerbated lymphangiogenesis, which can be reversed by topical application of recombinant human TSP-1.	21536744
Inflammation	Altered Intercellular Communication	Patients had critically colonised and/or infected, malodorous wounds, covered with slough/fibrin or wounds showing inflammation of the periwound skin.	21537301
Inflammation, Pain Distress Question	Altered Intercellular Communication	Inflammation was reduced in 60% (n=44) of cases and patients did not report pain or discomfort when using AM.	21537301
Inflammatory disease of mucous membrane, Irritable Bowel Syndrome	Altered Intercellular Communication	Recent studies support the hypothesis that postinfectious irritable bowel syndrome and some irritable bowel syndrome patients display persistent signs of minor mucosal inflammation.	21537540
Inflammation	Altered Intercellular Communication	By comparing the different types of isolated bacterial strains with the interleukin -8 (-251) and the histopathological data we observed that carriers of the A allele (AT and AA) infected by virulent strains (m1s1 cagA+) demonstrated a greater risk of presenting a degree of inflammation (OR = 24.75 CI 95% 2.29-267.20 P = 0.004) and increased neutrophilic activity (OR = 28.71 CI 95% 2.62-314 P = 0.002) in the gastric mucosa.	21537542
Infection caused by Helicobacter pylori	Altered Intercellular Communication	Our findings suggest that aberrant AID expression is correlated with persistent inflammatory condition induced by H. pylori infection and may contribute to the development of GC through an inflammatory condition and intestinalization.	21538122
Infarction, Inflammation	Altered Intercellular Communication	In conclusion, the TLR4 pathway is activated after MI and correlates with infarct severity but not with the extent of inflammation.	21538184
Inflammation, Esophageal carcinoma	Altered Intercellular Communication	Evidence is increasing that elevated systemic inflammation is associated with poor survival in patients with oesophageal carcinoma.	21538187
Malignant neoplasm of esophagus, Inflammation	Altered Intercellular Communication	The aim of the present study was to compare the predictive value of selected markers of systemic inflammation in patients who undergo surgical resection of oesophageal cancer.	21538187
Inflammation, Primary malignant neoplasm, Esophageal carcinoma	Altered Intercellular Communication	The present study indicates that the mGPS, an acute-phase protein-based prognostic score, better predicts cancer survival compared with the cellular components of systemic inflammation in patients with oesophageal carcinoma.	21538187
Degenerative polyarthritis, Inflammation, Pain Distress Question	Altered Intercellular Communication	Increased inflammation and pain are inseparable parts of knee osteoarthritis (OA) that may lead to disuse of the affected limb.	21538317
Degenerative polyarthritis, Inflammation, Atrophic, Myositis	Altered Intercellular Communication	Gene expression and the protein abundance of numerous muscle markers of inflammation and atrophy were elevated in patients with knee OA, and the increase in muscle inflammation was associated with a reduction in muscle strength.	21538317
Inflammation, Rhabdomyositis, Atrophic	Altered Intercellular Communication	Given the role inflammation markers may play in muscle strength and atrophy, further studies are needed to investigate the effect of exercise intervention on skeletal muscle inflammation.	21538317
Inflammation, Sample Size Calculation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Endothelial dysfunction and inflammation are pathogenic mechanisms common to systemic sclerosis (SSc) and atherosclerosis.	21538320
Inflammation, Vascular Diseases, Chronic Kidney Diseases	Altered Intercellular Communication	Insulin resistance, inflammation, and vascular disease in nondiabetic predialysis chronic kidney disease patients.	21538390
Cardiovascular morbidity, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD) is associated with high cardiovascular morbidity and mortality, which is not fully explained by traditional risk factors; hence, the interest in nontraditional risk factors such as inflammation and insulin resistance (IR).	21538390
Vascular Diseases, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Though IR is shown in nondiabetic CKD, its association with vascular disease and inflammation in this population is unknown, and is what this study aims to investigate.	21538390
Inflammation, Vascular Diseases, Chronic Kidney Diseases	Altered Intercellular Communication	IR and inflammation are related to vascular disease in nondiabetic predialysis CKD patients.	21538390
Inflammation, Endothelial dysfunction, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	Subjects with systemic inflammation were more insulin-resistant, and in nondiabetic predialysis CKD, IR and systemic inflammation were independently associated with endothelial dysfunction and atherosclerosis.	21538390
Inflammation, Necrosis, Granulation finding, Ulcer	Altered Intercellular Communication	DESIGN is a seven-item (depth, exudates, size, inflammation/infection, granulation, necrosis, and pocket) monitoring scale for pressure ulcers developed in 2002 by the scientific education committee of the Japanese Society of Pressure Ulcers.	21539648
Inflammation, Exudate, Necrosis	Altered Intercellular Communication	Weighting (-b value) for each item in order of the highest rank was: pocket, 2.289; size, 1.573; inflammation/infection, 0.778; granulation tissue, 0.682; exudate, 0.543; and necrotic tissue, 0.529.	21539648
Cessation of life, Hepatorenal Syndrome, Pneumonitis	Altered Intercellular Communication	Four deaths (15.4%) occurred: 3 due to perioperative progressing pulmonary infection/inflammation and 1 due to hepatorenal failure.	21540614
Angioedema, Bothered by Vomiting, Asthenia, Anemia, Nausea, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Cilengitide-related grade 3/4 AEs, all of which occurred after the DLT observation period, were anaemia, angioedema, asthenia, mucosal inflammation, nausea and vomiting (one event per category).	21540865
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	MRP8/14 is associated with systemic inflammation in stable coronary atherosclerosis in men.	21542848
Inflammation	Altered Intercellular Communication	The phagocyte activation marker MRP8/14 is significantly associated with markers of systemic inflammation in male patients with CAD.	21542848
Hypothalamic structure	Altered Intercellular Communication	Intake of trans fatty acids during gestation and lactation leads to hypothalamic inflammation via TLR4/NFkBp65 signaling in adult offspring.	21543208
Obesity, Hypothalamic structure	Altered Intercellular Communication	Thus, the present study shows that the mothers' hydrogenated vegetable fat intake during pregnancy and lactation led to hypothalamic inflammation and impaired satiety-sensing, which promotes deleterious metabolic consequences such as obesity, even after the withdrawal of the causal factor.	21543208
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	N-3 polyunsaturated fatty acids administration does not reduce the recurrence rates of atrial fibrillation and inflammation after electrical cardioversion: a prospective randomized study.	21543294
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	N-3 polyunsaturated fatty acids administration does not reduce the recurrence rates of atrial fibrillation and inflammation.	21543294
Ischemia, Inflammation	Altered Intercellular Communication	Remote intermittent ischemia before coronary artery bypass graft surgery: a strategy to reduce injury and inflammation?	21544683
Venous stenosis, Inflammation, Cardiac Arrhythmia, teratologic	Altered Intercellular Communication	The risk factors are as follows: inflammation or injury, vein anomalies, arrhythmia, venous stenosis.	21544979
Airway structure, Smoking	Altered Intercellular Communication	Smoking is thought to modify the pattern of airway inflammation.	21545371
Narcolepsy, Sleep Disorders	Altered Intercellular Communication	These sleep problems partly resemble core symptoms of narcolepsy, a sleep disorder caused by a general loss of the neurotransmitter hypocretin.	21546124
Airway structure, Asthma	Altered Intercellular Communication	Expiratory flows and airway inflammation in elderly asthmatic patients.	21546232
Airway structure, Asthma	Altered Intercellular Communication	We aimed to compare lung function and airway inflammation in elderly and younger asthmatic subjects.	21546232
Inflammation	Altered Intercellular Communication	Ongoing inflammation is associated with elevated levels of beta 2 microglobulin (B2M).	21546482
Electrocardiogram: myocardial infarction (finding), Arteritis	Altered Intercellular Communication	Coronary artery inflammation is a critical process in the pathogenesis of myocardial infarction (MI).	21547257
Encephalitis, Neurologic Deficits, Inflammation, Psychiatric	Altered Intercellular Communication	Consecutive children presenting over a 12-month period with newly acquired psychiatric and/or neurologic deficits consistent with anti-NMDAR encephalitis and evidence of central nervous system (CNS) inflammation were screened.	21547896
Inflammation, Complication Aspects	Altered Intercellular Communication	Application of the puncture-drainage interventions under ultrasonographic control, as well as lumbotomy and sequestrectomy, in the environment of aseptic inflammation, have permitted to escape purulent complications occurrence while an acute aseptic accumulations of liquid are present in bursa omentalis in 96.1% of patients and in cellular tissue of retroperitoneal space--in 69.6%.	21548323
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We then focused on the impairment of hepatocyte proliferation, oxidative stress, and inflammation as potential mechanisms accelerating the development of fibrosis in the elderly.	21548759
ARCN1 gene, Inflammation	Altered Intercellular Communication	Changes in protein metabolism and systemic inflammation may contribute to increased resting energy expenditure (REE) in COPD, leading to an energy imbalance and loss of fat and fat-free mass.	21550084
ARCN1 gene, Inflammation	Altered Intercellular Communication	The objective of this study was to determine first whether REE was increased in patients with COPD and, second, whether this was associated with increased protein turnover and/or systemic inflammation.	21550084
Retinal Degeneration, Ischemia, Inflammation	Altered Intercellular Communication	PEVAC may develop in absence of capillary ischemia or inflammation, probably due to progressive retinal endothelial cell degeneration.	21550688
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Biopsy revealed nonnecrotizing granulomatous inflammation with positive PTHrP staining by immunohistochemistry.	21550945
Inflammation, Specimen Type - Fistula, acute diverticulitis	Altered Intercellular Communication	Although most patients have experienced no prior episodes of acute diverticulitis, fistula formation is preceded by bouts of inflammation.	21551188
Virus Diseases, Myocarditis, Diabetes Mellitus	Altered Intercellular Communication	The mechanisms by which fulminant type 1 diabetes mellitus occurs is still uncertain, but the presence of islet injury accompanied by myocardial inflammation in the current case suggested that a viral infection accounted for the onset of this type of diabetes.	21551959
Inflammation, Kidney Diseases	Altered Intercellular Communication	Chronic inflammation plays a pivotal role in the development of renal disease.	21552189
Inflammation, Kidney Diseases	Altered Intercellular Communication	Awareness of other disturbed rhythms, such as inflammation processes, can affect the treatment of patients with renal disease.	21552189
Inflammation, Fibrosis Assessment, Tissue Adhesions	Altered Intercellular Communication	The most common reasons for conversion were severe adhesions caused by tissue inflammation (97 patients) and fibrosis of Calot's triangle (12 patients).	21552665
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Chronic inflammation has been considered a potential risk factor for prostate cancer.	21553150
Neurodegenerative Disorders, physiopathological	Altered Intercellular Communication	The increased dopaminergic tone created in the OBs of these patients could reflect a compensatory mechanism created by the early degeneration of other neurotransmitter systems and might contribute to the olfactory dysfunction exhibited by patients with neurodegenerative disorders.	21553300
Inflammation, Prediabetes syndrome, diabetic	Altered Intercellular Communication	Considering the involvement of chronic inflammation in the pathophysiology of DM, the present study investigated an association between the ACACB gene polymorphism and high-sensitivity C-reactive protein (hsCRP) in a prediabetic and diabetic population.	21553357
Inflammation	Altered Intercellular Communication	The present data suggest that the ACACB gene C>T polymorphism may therefore be associated with chronic inflammation in this population.	21553357
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Erectile dysfunction	Altered Intercellular Communication	Imbalanced low-grade inflammation and endothelial activation in patients with type 2 diabetes mellitus and erectile dysfunction.	21554550
Inflammation, Endothelial dysfunction, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Although a link among systemic inflammation, endothelial dysfunction, and ED is described in clinical situations mainly related with coronary heart disease (CHD) risk, evidences of this link in T2DM patients are rather limited.	21554550
Inflammation, Anger, Hostility	Altered Intercellular Communication	Trait anger, cynical hostility and inflammation in Latinas: variations by anger type?	21554946
Keratitis, Pseudomonas aeruginosa infection	Altered Intercellular Communication	TREM-1 amplifies corneal inflammation after Pseudomonas aeruginosa infection by modulating Toll-like receptor signaling and Th1/Th2-type immune responses.	21555403
Inflammation	Altered Intercellular Communication	While specific antiviral mechanisms remain to be elucidated, leflunomide shows unique bifunctional potential to both reduce viral load and, by virtue of its well-documented anti-inflammatory activity, attenuate the destructive inflammation associated with RSV disease.	21555813
Inflammation, Fibrosis Assessment, Asbestosis	Altered Intercellular Communication	The pathological features of asbestosis show the peribronchiolar fibrosis which suggest that asbestos fibers cause the inflammation of bronchioli.	21556185
Inflammation	Altered Intercellular Communication	Proliferative vitreoretinopathy (PVR), an eye-sight threatening complication of RRD surgery, resembles a wound-healing process with inflammation, scar tissue formation, and membrane contraction.	21556354
Gastroesophageal reflux disease, Collagen-vascular disease, Traumatic injury	Altered Intercellular Communication	Collagen-vascular disease, localized trauma, extraesophageal reflux (EER), and hormonal alterations have all been postulated as potential etiologies of iSGS.	21557240
Inflammatory Bowel Diseases, Gastrointestinal inflammation, Colitis	Altered Intercellular Communication	Fecal calprotectin (FC) is used as a marker for intestinal inflammation in inflammatory bowel disease (IBD) but there is no reliable marker for collagenous colitis (CC).	21557718
Airway structure, Asthma	Altered Intercellular Communication	Activated mast cell densities are increased on the airway smooth muscle in asthma where they may modulate muscle functions and thus contribute to airway inflammation, remodelling and airflow obstruction.	21557752
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	CBT significantly correlated with Brunt's fibrosis score (r = -0.49, P < 0.001) but not with steatosis (P = 0.23) or inflammation (P = 0.08).	21557768
Inflammation, Ischemic, Cerebrovascular accident	Altered Intercellular Communication	Does inflammation predispose to recurrent vascular events after recent transient ischaemic attack and minor stroke?	21557802
Inflammation, Ischemic	Altered Intercellular Communication	Inflammation is implicated in the pathogenesis and outcome of ischaemic injury.	21557802
Inflammation, Ischemic	Altered Intercellular Communication	Poststroke inflammation is associated with outcome but it remains unclear whether such inflammation precedes or results from ischaemic injury.	21557802
Cardiovascular Diseases	Altered Intercellular Communication	Interventions to reduce obesity-related inflammation may impact cardiovascular disease outcomes.	21558084
Viral myocarditis, Inflammation, Ventricular Dysfunction	Altered Intercellular Communication	In an animal model of viral myocarditis, plasma levels of thioredoxin and adiponectin have been reported to be associated with the severity of inflammation and recovery of ventricular dysfunction, respectively.	21558477
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Inflammation and polymorphonuclear neutrophils are shown to be important in the pathogenesis of acute myocardial infarction (AMI).	21558855
Multiple Organ Failure, Inflammation, Tissue injury, Colitis, Ischemic	Altered Intercellular Communication	The aim of the present study was to seek evidence for gut-derived signals in man in a group of eight patients undergoing elective abdominal aortic reconstruction, a procedure that is associated with sterile tissue injury, controlled colonic ischemia as a consequence of aortic cross-clamping, and a significant risk of developing systemic inflammation and multiple organ dysfunction syndrome.	21558985
Toxic effect	Altered Intercellular Communication	Investigation of systemic and mesenteric inflammatory signaling and gut-derived endothelial toxicity in patients undergoing high-risk abdominal aortic surgery.	21558985
Weight decreased, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Our data suggest that the RYGB surgery, beyond weight loss, induces early beneficial hormonal changes which favor glycemic control in type 2 diabetes.	21559794
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Intracolonic infusion of fecal supernatants from ulcerative colitis patients triggers altered permeability and inflammation in mice: role of cathepsin G and protease-activated receptor-4.	21560201
Inflammation	Altered Intercellular Communication	However, the mechanisms through which Cat-G triggers inflammation are not fully elucidated.	21560201
Inflammation, Gastric metaplasia	Altered Intercellular Communication	Morphologically at 15% of the patients with gastric metaplasia was found moderate inflammation.	21560383
Chronic infectious disease, Inflammation, Esophagitis	Altered Intercellular Communication	Esophagitis in chronic viral infections was characterized by a higher frequency of erosive changes, higher activity of inflammation.	21560383
Inflammation	Altered Intercellular Communication	Prescribe a higher rate of airflow obstruction in older compared with patients younger than 60 years (from 65.5 and 39.8% respectively, p < 0.05), which increased with the duration of the disease Yak (in the elderly to a greater extent than in patients younger than 60 years), had no clear connection with the extent of inflammation in the intestine, while staying within 60-71.4% at any site of inflammation.	21560623
Inflammation, Primary malignant neoplasm, Cardiovascular Diseases, Diabetes Mellitus, nervous system disorder, Chronic disease, Lung diseases	Altered Intercellular Communication	Inflammation, although first characterized by Cornelius Celsus, a physician in first Century Rome, it was Rudolf Virchow, a German physician in nineteenth century who suggested a link between inflammation and cancer, cardiovascular diseases, diabetes, pulmonary diseases, neurological diseases and other chronic diseases.	21561421
Inflammation, Chronic disease	Altered Intercellular Communication	Extensive research within last three decades has confirmed these observations and identified the molecular basis for most chronic diseases and for the associated inflammation.	21561421
Inflammation, Chronic disease	Altered Intercellular Communication	Thus agents that can inhibit NF-kappaB and diminish chronic inflammation have potential to prevent or delay the onset of the chronic diseases and further even treat them.	21561421
Inflammatory abnormality of the eye, Choroiditis	Altered Intercellular Communication	Extradigestive manifestations can occur, especially ocular inflammation, but posterior choroidal inflammation is more unusual.	21561686
Inflammation, Restenosis	Altered Intercellular Communication	This study investigated whether markers of inflammation and the adipo-insular axis associated with T2DM and poor metabolic control were able to predict restenosis after PCI in T2DM patients.	21562066
Inflammation, Restenosis	Altered Intercellular Communication	Fasting glucose prior to the PCI was an independent predictor of restenosis in patients with T2DM while analyses of a variety of markers related to inflammation and the adipo-insular axis did not add any further information.	21562066
Malignant Neoplasms	Altered Intercellular Communication	Previously, chitinase 3-like 1 (CHI3L1) protein level was increased in various inflammatory conditions and cancers.	21562723
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Common genetic variants in the Toll-like receptor 4 (TLR4), which is involved in inflammation and immune response pathways, may be important for prostate cancer.	21563195
Inflammation, Edema	Altered Intercellular Communication	However, changes in WC due to inflammation and edema may also affect the MTR.	21563257
Inflammation, Edema	Altered Intercellular Communication	MTR was correlated with WC in MS tissue, indicating that inflammation and edema influence MTR.	21563257
Inflammation, Mucosal Infection	Altered Intercellular Communication	In most cases the inflammation is connected with nasal mucosa infection.	21563449
Periapical bone loss	Altered Intercellular Communication	It is most often connected with periapical lesions, complications following dental procedures and oroantral fistula inflammation.	21563449
Communicable Diseases, Inflammation	Altered Intercellular Communication	Endpoints assessed were tube exposure, graft thinning, graft clarity, graft-related infection, and inflammation.	21563743
Hepatic inflammation, Hyperferritinaemia	Altered Intercellular Communication	Persistent hyperferritinaemia seems to be a risk biomarker of GMA in patients with PCT, probably in the setting of chronic iron overload and hepatic inflammation.	21564073
Inflammation, Inflammatory dermatosis, Pustulosis of Palms and Soles	Altered Intercellular Communication	The acrosyringium is the target for inflammation in the chronic and intensely inflammatory skin disease palmoplantar pustulosis (PPP).	21564193
ARCN1 gene, Chronic Obstructive Airway Disease, Airway Obstruction, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airway obstruction and persistent chronic airway inflammation and is influenced by genetic and environmental factors.	21565178
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation and immune response play an important role in the pathogenesis of atherosclerosis.	21565239
Inflammatory Bowel Diseases, Inflammation, Colorectal Carcinoma, Neoplasms	Altered Intercellular Communication	Inflammatory bowel disease (IBD) increases the risk of colorectal cancer (CRC), indicating that inflammation might alter tumor characteristics and potentially affect treatment and survival.	21565283
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Epicardial adipose tissue has been linked to cardiovascular metabolism and inflammation and has been shown to predict prevalence and progression of coronary artery disease.	21565323
Inflammation, Fibrosis Assessment, Tubular atrophy, Allograft surgical material	Altered Intercellular Communication	Inflammation, interstitial fibrosis (IF), and tubular atrophy (TA) precede chronic transplant dysfunction, which is a major cause of renal allograft loss.	21566051
Inflammation	Altered Intercellular Communication	Here, we studied PTC number, IF/TA, inflammation, and renal function in 48 patients who underwent protocol biopsies.	21566051
Inflammation	Altered Intercellular Communication	Fewer PTCs in the 3-month biopsy correlated with high IF/TA and inflammation scores and predicted lower renal function at 1 year.	21566051
Necrotizing granulomatous inflammation, Schistosoma	Altered Intercellular Communication	Biopsy of the mass showed transmural granulomatous inflammation interpreted as schistosomal granuloma, ruling out lymphoma.	21566088
Cessation of life, Inflammation	Altered Intercellular Communication	Cell death, inflammation and loss of proteoglycans participate in these mechanisms with p38MAPK being one of the pivotal signaling kinases.	21567074
Inflammation, Gastritis	Altered Intercellular Communication	These data in humans with and without gastritis are consistent with the hypothesis that local factors influence ectopic gastric IF expression, arising from either the anatomical location, the focal inflammation, or both.	21567190
Inflammation	Altered Intercellular Communication	Additionally, this case reinforces the hypothesis that local inflammation has a pathogenic role.	21567376
Inflammation, Ototoxicity, Ischemic stroke	Altered Intercellular Communication	These findings suggest that neuroprotective properties of neuroserpin may be related to the inhibition of excitotoxicity, inflammation, as well as blood brain barrier disruption that occur after acute ischemic stroke.	21569344
Inflammation	Altered Intercellular Communication	The prevalence of C. tropicalis significantly increased with the highest degree of inflammation (P < .05).	21569989
Inflammation, Spinal Cord Injuries	Altered Intercellular Communication	Systemic inflammation and reduced pulmonary function in chronic spinal cord injury.	21570031
Inflammation, Spinal Cord Injuries, Stanford Cancer Institute	Altered Intercellular Communication	To evaluate the relationship between systemic inflammation and pulmonary function in persons with chronic spinal cord injury (SCI).	21570031
Inflammation, Stanford Cancer Institute, Neuromuscular	Altered Intercellular Communication	These results suggest that the reduction of pulmonary function after SCI is related not only to neuromuscular impairment but also to factors that promote systemic inflammation.	21570031
Inflammation	Altered Intercellular Communication	High mobility group chromosomal protein B1 (HMGB1) and N2 (HMGN2), two members of high mobility group (HMG) family, play important role in inflammation.	21570059
Inflammation, Thrombosis	Altered Intercellular Communication	Endothelial function represents a crucial factor for the regulation of vascular tonus and its malfunction influences the formation of thrombosis and inflammation.	21570519
Cardiovascular morbidity, Inflammation, Peripheral Arterial Diseases	Altered Intercellular Communication	Subjects with peripheral artery disease (PAD) are at increased risk of cardiovascular morbidity and mortality, perhaps in part, related to increased levels of inflammation, platelet activity, and lipids.	21570531
Hepatic inflammation, hepcidin, Fatty Liver Disease	Altered Intercellular Communication	No associations between hepatic inflammation/iron content on liver biopsy and variables of lipid metabolism were found but hepcidin correlated with hepatic inflammation in all patients and with NAS scores in NASH.	21570653
Inflammation, Fatty Liver Disease	Altered Intercellular Communication	The correlation of H with sd-LDL and IRI, without relation to hepatic iron content suggests a putative link between inflammation, carbohydrate and lipid metabolism in NASH.	21570653
Inflammation, Small bowel bacterial overgrowth syndrome, Immunocompromised Host, Restless Legs Syndrome, hepcidin	Altered Intercellular Communication	Three hypotheses developed are (a) RLS patients are selectively immunocompromised or genetically predisposed and thus more subject to SIBO; (b) SIBO leads to autoimmune changes, and subsequent auto-antibodies attack brain and/or peripheral nerves and (c) SIBO inflammation leads to increased hepcidin and CNS iron deficiency which, in turn, leads to RLS.	21570907
Inflammation, Obesity	Altered Intercellular Communication	They are increasingly determined by low-grade inflammation, independently of central obesity.	21571245
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	No association between markers of inflammation and osteoarthritis of the hands and knees.	21572158
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Local inflammation plays a prominent role in osteoarthritis (OA).	21572158
Inflammation, Viremia	Altered Intercellular Communication	Regardless of aggressive screening, peak viremia and inflammation occurred before enrollment and potential intervention.	21573003
Inflammation, Necrosis, Autoimmune Diseases, Pulmonary Emphysema, Chronic Obstructive Airway Disease	Altered Intercellular Communication	These data suggest that higher expression of CD46 in the lungs of ex-smoker protects them from emphysema and chronic obstructive pulmonary disease by clearing the inflammation impeding the proliferation of CD8(+) T cells and necrosis, achieved by production of T regulatory cells and degradation of C3b; restraining the complement cascade favors apoptosis over necrosis, protecting them from autoimmunity and chronic inflammation.	21573156
Gastric mucosa, Carcinogenesis, Gastritis	Altered Intercellular Communication	This study was executed to prove the existence of c-Kit-positive interstitial cells of Cajal (ICC)-like cells [c-Kit (+) ICC-like cells] and their possible role associated with gastric inflammation and/or carcinogenesis in human gastric mucosa.	21573494
Infection, EBV-Related Sarcoma	Altered Intercellular Communication	Intrathecal EBV activity is not restricted to typical EBV-related disorders, unexpectedly frequent in further CNS infections and also present in non-inflammatory conditions.	21573818
Inflammation, Carcinogenesis, Neoplasms	Altered Intercellular Communication	Apoptosis and induction of inflammation by tumor released cytokines as tumor escape mechanisms have been proposed to play an important role in colorectal carcinogenesis.	21573932
Neoplasms	Altered Intercellular Communication	TNF-a expression by tumor cells may be an efficient immunological escape mechanism by inflammation-enhanced metastases and probably by induction of apoptosis in tumor-infiltrating CD8+ immune cells resulting in a down regulation of the tumoral immune response.	21573932
Hypophysitis, CTCAE, Inflammation, Disease, Pituitary Function Tests	Altered Intercellular Communication	Hypophysitis is an inflammation of the pituitary gland and includes a heterogeneous group of diseases presenting with impaired pituitary gland function.	21574123
Communicable Diseases, Inflammation, Necrosis, Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation with fibrinoid necrosis was present in 47% of lesions in patients with M. marinum infection and suppurative granulomatous inflammation was noted in 45% of patients with RGM infection.	21575304
Inflammation	Altered Intercellular Communication	Xanthogranulomatous inflammation of ascending colon with mucosal involvement: report of a first case.	21575889
Inflammation	Altered Intercellular Communication	Xanthogranulomatous inflammation (XGI) is a rare phenomenon and can involve any organ system.	21575889
Inflammation	Altered Intercellular Communication	CSF inflammation persisted and a gradual increase in granulation tissue was found in the subdural space on lumbar MRI.	21576840
Gingivitis	Altered Intercellular Communication	Clinical examination revealed marked gingival inflammation, moderate gingival recession and mobility of some of his lower anterior teeth: 31, 32, and 33.	21577000
Inflammation, Arteritis	Altered Intercellular Communication	Quantification of supra-aortic arterial wall inflammation in patients with arteritis using high resolution dynamic contrast-enhanced magnetic resonance imaging: initial results in correlation to [18F]-FDG PET/CT.	21577125
Inflammation, Arteritis	Altered Intercellular Communication	: DCE-MRI is able to measure arterial inflammation reliably and noninvasively with good correlation to [F]-FDG PET/CT in patients suffering from arteritis of the supraaortic arteries.	21577125
Fibrosis Assessment, Pancreatitis, Chronic	Altered Intercellular Communication	Recently, two studies on rats reported that tobacco smoking is associated with chronic pancreatic inflammation with fibrosis and scarring of pancreatic acinar structures.	21577244
Intestinal metaplasia, Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Increased gastric osteopontin expression by Helicobacter pylori Infection can correlate with more severe gastric inflammation and intestinal metaplasia.	21585607
Intestinal metaplasia	Altered Intercellular Communication	The study validated whether OPN expressions correlate with Helicobacter pylori-related chronic gastric inflammation and the precancerous change as intestinal metaplasia (IM).	21585607
Gastritis	Altered Intercellular Communication	For the H. pylori-infected subjects, the gastric inflammation was assessed by the Updated Sydney System.	21585607
Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	For the H. pylori-infected patients, an increased OPN expression correlated with more severe chronic gastric inflammation (p < .001) and the presence of IM (OR: 2.6, 95% CI: 1.15-5.94, p = .02).	21585607
Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Increased gastric OPN expression by H. pylori infection can correlate with a more severe gastric inflammation and the presence of IM.	21585607
Inflammation, Negative Regulation of Cell Cycle	Altered Intercellular Communication	For this purpose, markers for inflammation (COX-2, CD3, CD8), apoptosis (p53), cell cycle arrest (p53, p21), proliferation (Ki67), and angiogenesis (CD31) were examined.	21585654
Inflammation, Fibrous	Altered Intercellular Communication	No loose BONIT-HA particles or delamination of the coating were observed, and there was no inflammation or fibrous interposition at the interface.	21586774
Infertility, Neoplasms	Altered Intercellular Communication	Organ-sparing surgery for the contralateral testicular tumor following orchiectomy, can be considered to avoid infertility and hormonal substitutions.	21586887
Inflammation, Rupture	Altered Intercellular Communication	The mass had gradually enlarged for a 25-year period without inflammation or rupture.	21586972
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Plasma markers of inflammation, coagulation and angiogenesis were measured.	21587257
Inflammation, Acute onset pain	Altered Intercellular Communication	Interestingly, AKT2 mRNA was up-regulated in patients with acute pain during the first 12 months, indicating that AKT2 transcriptional activation may be associated with acute rather than chronic inflammation and phagocytosis.	21590431
Inflammation	Altered Intercellular Communication	The authors propose the choice of applied surgical technique by taking into account difficulties consequential to the anatomy of this region, as well as additional complications regarding the chronic inflammation process.	21591367
Granulomatous inflammation	Altered Intercellular Communication	Her serum PR3-ANCA titer was high, and granulomatous inflammation with Langhans giant cell was noted in a transbronchial biopsy specimen.	21591462
Sample Size Calculation, Inflammation, Left ventricular diastolic dysfunction, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Overproduction of collagen in SSc results in diastolic left ventricular dysfunction, while generalized inflammation in SLE and DPM leads mainly to pathologic changes on valvular leaflets and/or pericardium.	21591573
Acute Coronary Syndrome, vascular inflammations	Altered Intercellular Communication	Studies have identified that MRP8/14 regulates vascular inflammation and serves as a novel marker of acute coronary syndrome.	21592353
Diastolic dysfunction, Inflammation	Altered Intercellular Communication	The association between inflammation and left ventricular (LV) diastolic dysfunction in continuous ambulatory peritoneal dialysis (CAPD) and non-CAPD patients is not established.	21592755
Diastolic dysfunction, Inflammation	Altered Intercellular Communication	The objective of this study was to test the above association and whether inflammation interacts with CAPD to increase LV diastolic dysfunction risks.	21592755
Diastolic dysfunction, Inflammation, Left ventricular diastolic dysfunction	Altered Intercellular Communication	In a multivariate regression analysis adjusting for all the factors associated with LV diastolic dysfunction, inflammation is still significantly associated with left ventricular diastolic dysfunction (TNF-alpha, OR: 2.6, 95% CI: 2.0-3.35, p < 0.001; IL-6, OR: 1.26, 95% CI: 1.25-1.26, p = 0.01).	21592755
Diastolic dysfunction, Inflammation	Altered Intercellular Communication	In addition, the interaction of CAPD and inflammation significantly contributed to the development of LV diastolic dysfunction (CAPD* TNF-a: OR: 1.45, 95% CI: 1.13-1.79, P = 0.004).	21592755
Diastolic dysfunction, Inflammation	Altered Intercellular Communication	We found inflammation plays a vital role for LV diastolic dysfunction especially in CAPD patients.	21592755
Diastolic dysfunction, Inflammation	Altered Intercellular Communication	A synergistic effect between CAPD and inflammation, especially TNF-a, would further aggravate LV diastolic dysfunction.	21592755
Rheumatoid Arthritis, Inflammation, Inflamed joint	Altered Intercellular Communication	IL-27-producing CD14(+) cells infiltrate inflamed joints of rheumatoid arthritis and regulate inflammation and chemotactic migration.	21592822
Hepatitis, Liver Cirrhosis	Altered Intercellular Communication	The IL28B rs12979860 CC genotype is associated with a higher prevalence of cirrhosis in HIV-HCV-coinfected patients than CT/TT genotypes, suggesting that IL28B CC carriers may experience a more rapid progression of HCV-related liver fibrosis, perhaps as result of increased liver inflammation.	21592993
Hypophysitis, CTCAE, Inflammation	Altered Intercellular Communication	Hypophysitis is a chronic inflammation of the pituitary gland that comprises an increasingly complex clinicopathological spectrum.	21593109
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation.	21593200
Inflammation, Kidney	Altered Intercellular Communication	We investigated whether Klotho levels and signaling modulate inflammation in diabetic kidneys.	21593200
Inflammation	Altered Intercellular Communication	There was no evidence of multicellular micrometastases sufficiently large to require angiogenesis and no associated inflammation was observed.	21593344
Meckel Diverticulum, Congenital Abnormality, Gastrointestinal Hemorrhage, Intestinal Obstruction, Acute inflammation	Altered Intercellular Communication	Meckel diverticulum is the most common congenital anomaly of the small intestine that generally comes to attention due to a variety of complications, such as gastrointestinal tract bleeding, bowel obstruction or acute inflammation.	21594546
Inflammation, Atrophic	Altered Intercellular Communication	Furthermore, the levels of histological parameters of activity, inflammation, and atrophy in the gastric corpus, but not in the gastric antrum, were significantly more severe in responders than in nonresponders,.	21594563
Idiopathic hypertrophic pachymeningitis, Bone Marrow Diseases, Proliferative inflammation, Pain Distress Question	Altered Intercellular Communication	Idiopathic hypertrophic spinal pachymeningitis (IHSP) is a comparatively rare disease characterized by hypertrophic inflammation of the dura mater and clinical symptoms that progress from local pain to myelopathy.	21594749
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	It can be inferred that inflammation may be involved in the processes of LUTS.	21594882
Inflammation, Elastoid degeneration	Altered Intercellular Communication	Inflammation was more pronounced in blurred OCT images, whereas solar elastosis dominated in easily identified lesions.	21595042
Renal Insufficiency, Inflammation, Malignant Neoplasms, Liver Dysfunction	Altered Intercellular Communication	Plasma YB-1/p18 can identify patients with malignancies, independent of acute inflammation, renal impairment or liver dysfunction.	21595987
Inflammation, Hypoadiponectinemia, Aortic Valve Stenosis	Altered Intercellular Communication	Hypoadiponectinemia is associated with valvular inflammation and faster disease progression in patients with aortic stenosis.	21597293
Aneurysm, Inflammation	Altered Intercellular Communication	This aneurysm was firm and thick and adhered to some organs due to inflammation.	21597420
Inflammation, Bacterial Infections, Acute otitis media	Altered Intercellular Communication	Acute otitis externa (AOE) (swimmer's ear) is inflammation of the external auditory canal most often caused by bacterial infection.	21597452
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	We tested whether 25(OH)D concentration is associated with markers of vascular remodeling and inflammation in African American ESRD patients.	21600051
Inflammation, Depression, CTCAE, atherosclerotic	Altered Intercellular Communication	Depression and inflammation have been suggested to be involved in the atherosclerotic processes, but empirical evidence is mixed.	21600662
Inflammation, Bipolar Disorder, Atherosclerosis	Altered Intercellular Communication	We tested the hypothesis that depressive symptoms are associated with atherosclerosis only when combined with other risk factors, such as inflammation indicated by indoleamine 2,3-dioxygenase (IDO) activation.	21600662
Carotid Atherosclerosis, Inflammation, Bipolar Disorder	Altered Intercellular Communication	These data suggest that depressive symptoms are associated with preclinical y carotid atherosclerosis only if they are linked to inflammation, and that this association is present only in women.	21600662
Inflammation, Helicobacter pylori	Altered Intercellular Communication	Helicobacter pylori (H. pylori) is a Gram-negative bacterium that is well known in the involvement of chronic inflammation in the gastric mucosa of the human stomach.	21604199
Inflammation, Depression, CTCAE, Suicide	Altered Intercellular Communication	Inflammation has been linked to depression and suicide risk.	21605657
Inflammation	Altered Intercellular Communication	Chronic inflammation was found to play an important role in the development of cardiovascular risk factors.	21605731
Lichen Planus, Inflammation, Dyslipidemias	Altered Intercellular Communication	Chronic inflammation in patients with lichen planus may explain the association with dyslipidemia.	21605731
Inflammation, Dental Plaque	Altered Intercellular Communication	Inflammation plays a crucial role in plaque vulnerability.	21605863
Arterial Stiffness, Inflammation	Altered Intercellular Communication	In healthy subjects without confounding risk factors or significant systemic inflammation, a high cystine level, reflecting extracellular oxidant burden, is associated with increased arterial stiffness and wave reflections.	21605864
Neuronal degeneration, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) is a neurodegenerative process characterized by progressive neuronal degeneration, reduced levels of neurotransmitters, and altered forms of synaptic plasticity.	21606570
Inflammation	Altered Intercellular Communication	Both disease activity and cumulative damage scores did not change after the intervention, and no evidence of exercise-induced exacerbation of inflammation was observed.	21606873
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Dietary inflammation factor rating system and risk of Alzheimer disease in elders.	21606905
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	It has been suggested that inflammation is involved in Alzheimer disease (AD) pathogenesis.	21606905
Inflammation, Data types - Address	Altered Intercellular Communication	In addition, although it remains possible that tIFR might be related with some other aspects of inflammation not captured by hsCRP, lack of association with AD risk suggests its limited clinical utility.	21606905
Degenerative polyarthritis, Inflammatory disorder	Altered Intercellular Communication	This study suggests that short-term (2 weeks) calcium fructoborate supplementation in patients with osteoarthritis symptoms has a favorable prognosis on inflammation diseases.	21607703
Refractory Cytopenia of Childhood, Inflammation	Altered Intercellular Communication	Our data allow us to conclude that the control of tumor-associated inflammation is an important therapeutic principle in patients with metastatic RCC.	21607771
Inflammation	Altered Intercellular Communication	This leads to the idea that ageing is a result of a chronic inflammation process and to the term "inflammageing".	21607797
Inflammation	Altered Intercellular Communication	This leads to the idea that ageing is a result of a chronic inflammation process and to the term "inflammageing".	21607797
Arthritis	Altered Intercellular Communication	Additionally, approximately 30% of the synovial FOXP3(+) T cells were Ki67(+) and hence actively dividing, but proliferation did not overlap with cytokine production, suggesting that these cells represent functional Tregs having met their cognate antigen and expanded in an attempt to alleviate joint inflammation.	21607944
Inflammation, Edema	Altered Intercellular Communication	He had occasional mild edema of the right leg, but no signs of inflammation or recurrence of the angiomyomas.	21609161
Inflammation, Fibrosis Assessment, Congestive heart failure	Altered Intercellular Communication	The authors found significant increases in myocyte size, myocardial fibrosis, and inflammation in both CHF groups who underwent CRT or LVAD, compared with healthy controls.	21609388
Inflammation, Hypomagnesemia, Metabolic Syndrome X	Altered Intercellular Communication	Severe hypomagnesemia and low-grade inflammation in metabolic syndrome.	21609903
Inflammation, Primary malignant neoplasm, Intrahepatic bile duct	Altered Intercellular Communication	An increased intrahepatic bile duct pressure following cholecystectomy might cause chronic inflammation in the surrounding liver tissue, which might induce cancer development.	21610710
Inflammation, Stomach ache, Anorexia	Altered Intercellular Communication	These were stomach ache, loss of appetite, lethargy and inflammation of the face and body.	21610855
Inflammation, physiopathological	Altered Intercellular Communication	Based on these findings we argue that GATA3 serves as a key regulator in psoriatic inflammation, keratinocyte hyperproliferation and skin barrier dysfunction.	21611195
Inflammation	Altered Intercellular Communication	Consistent with previous observations, a barrier defect and frequent infiltration of neutrophils was observed, suggesting that focal p120 loss generates a microenvironment disposed to chronic inflammation.	21611205
Inflammation	Altered Intercellular Communication	Given that byproducts of inflammation are known to be highly mutagenic, we suggest that tumorigenesis in this model is ultimately driven by the lifelong inability to heal chronic wounds and the substantially increased rates of stochastic gene mutation in tissue microenvironments subjected to chronic inflammation.	21611205
Interstitial inflammation	Altered Intercellular Communication	Kidney biopsy revealed expanded mesangium, thickened capillary loops and epimembranous spikes, with no significant interstitial inflammation or thickened tubular basement membranes.	21612326
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Low-fructose diet lowers blood pressure and inflammation in patients with chronic kidney disease.	21613382
Inflammation, Hypertension, CTCAE, Hyperuricemia	Altered Intercellular Communication	Fructose has been strongly linked with hypertension, hyperuricemia and inflammation in experimental models and humans.	21613382
Inflammation, Hyperuricemia, Kidney Diseases, Chronic Kidney Diseases	Altered Intercellular Communication	However, the effect of low-fructose diet on inflammation, hyperuricemia and the progression of renal disease has not yet been evaluated in patients with chronic kidney disease (CKD).	21613382
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Low-fructose diet in subjects with CKD can reduce inflammation with some potential benefits on BP.	21613382
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Moreover, associations between serum 25(OH)D and metabolic syndrome (MetSyn), insulin resistance (IR), and inflammation are unclear in children.	21613551
Inflammation, Fibrosis Assessment, Calcinosis	Altered Intercellular Communication	Thus, fetuin-A levels are influenced by chronic inflammation and actively affect fibrosis and calcification processes, respectively.	21613794
Inflammation, Fibrosis Assessment, Calcinosis, Tubular atrophy, Renal Allograft Thrombosis	Altered Intercellular Communication	Graft rejection, interstitial fibrosis and tubular atrophy, chronic inflammation and calcification are common causes for kidney allograft loss.	21613794
Carcinomatosis, Inflammation, Fibrosis Assessment, borderline ovarian tumor	Altered Intercellular Communication	Diffuse intraabdominal fibrosis and inflammation mimicking peritoneal carcinomatosis recurred after surgery for borderline ovarian tumor misdiagnosed by 18F-fluorodeoxyglucose-positron emission tomography.	21614927
Inflammation, Fibrosis Assessment, borderline ovarian tumor	Altered Intercellular Communication	Based on imaging and intraoperative findings, multiple intraabdominal masses strongly suggested peritoneal recurrence from a previous ovarian borderline tumor, but it finally proved to be inflammation and fibrosis on histopathologic examination.	21614927
Inflammation	Altered Intercellular Communication	Therefore, the possibility of a false-positive diagnosis due to benign conditions, such as inflammation, should always be taken into consideration.	21614927
Colonic Diseases, Functional, Paraganglioma	Altered Intercellular Communication	Postoperatively, patients with paragangliomas should receive hormonal evaluation for functional disease, imaging evaluation for multicentric and metastatic disease, and genetic counseling.	21615305
Inflammation, SLC22A5 gene	Altered Intercellular Communication	Chronic inflammation also plays an important role in the pathophysiology of SCD.	21615396
Inflammation, Greeks, SLC22A5 gene	Altered Intercellular Communication	We aimed to investigate endothelial activation in Caucasian Greek patients with SCD by means of measuring adhesion molecules and markers of inflammation.	21615396
Inflammation	Altered Intercellular Communication	Our findings demonstrate the high degree of endothelial activation and damage seen in sickle cell patients even in steady-state condition, as well as the important chronic inflammation underlying the pathophysiology of this widespread disease.	21615396
Pneumonitis	Altered Intercellular Communication	Aged mice had increased lung inflammation as determined by cytokine analysis and histopathology of lung sections.	21615674
Inflammation, Pneumonia	Altered Intercellular Communication	Genotoxic stress induced by bleomycin and oxidative stress enhanced susceptibility of young mice to pneumonia and was positively correlated with enhanced p16, inflammation, and LR levels.	21615674
Hermanski-Pudlak Syndrome, Pneumonitis	Altered Intercellular Communication	Early alveolar epithelial dysfunction promotes lung inflammation in a mouse model of Hermansky-Pudlak syndrome.	21616998
Inflammation, Hermanski-Pudlak Syndrome, Hantavirus Infections	Altered Intercellular Communication	The pulmonary phenotype of Hermansky-Pudlak syndrome (HPS) in adults includes foamy alveolar type 2 cells, inflammation, and lung remodeling, but there is no information about ontogeny or early disease mediators.	21616998
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	EPPE mice develop increased total lung phospholipid, followed by a macrophage-predominant pulmonary inflammation, and lung remodeling including fibrosis.	21616998
Inflammation, Pneumonitis, Hantavirus Infections	Altered Intercellular Communication	Inflammation is initiated from the abnormal alveolar epithelial cells in HPS, and S-nitrosylated SP-D plays a significant role in amplifying pulmonary inflammation.	21616998
Inflammation	Altered Intercellular Communication	However, there were no positive inflammation signals and no clear elevated rheuma-immunology.	21617278
Airway structure	Altered Intercellular Communication	FeNO, as a marker of airway inflammation, ACT score, and the results of spirometry have been evaluated after switching to maintenance therapy by FBC 640/18 mg/day for 8 weeks.	21617360
Inflammation, Liver carcinoma	Altered Intercellular Communication	Analysis of factors affecting recurrence of hepatocellular carcinoma after liver transplantation with a special focus on inflammation markers.	21617590
Inflammation, Liver neoplasms	Altered Intercellular Communication	Systemic inflammation markers, such as neutrophil-to-lymphocyte ratio (NLR), have recently emerged as the prognostic factors for recurrence of liver tumors.	21617590
Intraocular inflammation	Altered Intercellular Communication	We recently demonstrated that aA-crystallin, a molecular chaperone, protected photoreceptors from apoptotic signals in intraocular inflammation.	21617844
White matter, Lupus Erythematosus	Altered Intercellular Communication	Neuroimaging evidence of white matter inflammation in newly diagnosed systemic lupus erythematosus.	21618460
Inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	The primary pathophysiology of CNS involvement in SLE is thought to be inflammation secondary to autoantibody-mediated vasculitis.	21618460
Inflammation, Atrophic, Hypometabolism	Altered Intercellular Communication	Neuroimaging studies have shown hypometabolism (representing impending cell failure) and atrophy (representing late-stage pathology), but not inflammation.	21618460
Inflammation, Hypermetabolism, Atrophic, Hypometabolism	Altered Intercellular Communication	The purpose of this study was to detect the presence and regional distribution of inflammation (hypermetabolism) and tissue failure, apoptosis, or atrophy (hypometabolism).	21618460
Inflammation, Hypermetabolism, Inflammatory disorder	Altered Intercellular Communication	The SELENA-SLEDAI-correlated increases in glucose consumption are potential evidence of inflammation, consistent with prior reports of hypermetabolism in inflammatory disorders.	21618460
Inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	To our knowledge, this is the first imaging-based evidence of SLE-induced CNS inflammation in an SLE inception cohort.	21618460
Inflammation, Ulcerative Colitis, Colitis	Altered Intercellular Communication	In ulcerative colitis (UC) patients, the median Simple Clinical Colitis Activity Index (SCCAI) was 4 (range 0-10) in mild and 6 (range 0-14) in patients with moderate or severe endoscopic activity of inflammation (p = 0.002).	21619483
Crohn Disease, Inflammatory disease of mucous membrane	Altered Intercellular Communication	In Crohn's disease (CD) patients, there was no statistical significant association between the Harvey-Bradshaw Index (HBI) and the endoscopic grade of mucosal inflammation (p = 0.8).	21619483
Inflammation, vinyltriethoxysilane	Altered Intercellular Communication	Thus far, a causal relationship between inflammation and VTE remains to be clarified and more prospective data are warranted.	21620438
Inflammation, Ovarian Serous Adenocarcinoma, Malignant Neoplasms	Altered Intercellular Communication	Two cases with suspicion for malignancy underwent conversion to laparotomy (2.1%), and frozen sections revealed serous ovarian adenocarcinoma (n=1) and chronic inflammation (n=1).	21620559
Malignant neoplasm of skin, Inflammation	Altered Intercellular Communication	Environmental and endogenous stresses to skin are considered causative reasons for skin cancers, premature ageing, and chronic inflammation.	21620684
Encephalitis, Vasculitis, CTCAE	Altered Intercellular Communication	Pathological evidence of both vasculitis and encephalitis has never been previously reported in any inflammatory condition affecting the brain.	21620774
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	Cholesterol crystals have been shown to cause inflammation, and ultimately atherosclerotic lesions through the activation of the NLRP3 inflammasome.	21621776
Infarction, Inflammation	Altered Intercellular Communication	Restricted diffusion in the optic nerve detected with MRI has been previously reported in infarction and inflammation but not in infiltrative neoplasm.	21623229
Inflammation, Neoplasms	Altered Intercellular Communication	Acute inflammation markers and tumor stimulating factors may not reflect clinical benefits of laparoscopic surgery.	21623607
Inflammation, Irritation	Altered Intercellular Communication	Because inflammation is a factor promoting ageing, all-trans retinoic acid (RA)-induced irritation may have a negative influence on collagen accumulation in human skin despite its stimulation of collagen production.	21623752
Refractory anemias, Inflammation	Altered Intercellular Communication	Excessive RA-induced inflammation might prevent collagen accumulation in aged skin despite the positive effect of RA on collagen production.	21623752
Inflammation, Pathologic Neovascularization, Calcinosis	Altered Intercellular Communication	Neovascularity and calcification were seen in 1 lesion and mild to moderate inflammation was seen in 3 lesions.	21624622
Inflammation	Altered Intercellular Communication	Neutrophil gelatinase-associated lipocalin (NGAL) is released by renal tubular cells in response to inflammation and injury.	21624735
Inflammation	Altered Intercellular Communication	These results suggest that uric acid contributes to systemic inflammation in humans and are in line with experimental data showing that uric acid triggers sterile inflammation.	21625475
Inflammation	Altered Intercellular Communication	CD163, a haptoglobin-hemoglobin (Hp-Hb) scavenger receptor, expressed by monocytes and macrophages, is important in resolution of inflammation.	21625498
HIV Antigens	Altered Intercellular Communication	Our findings clarify technical issues regarding CD163 expression on monocyte subsets and further elucidates its role in HIV-associated inflammation by demonstrating that CD163 is readily lost from CD14++CD16- monocytes and induced in pro-inflammatory CD14+CD16++ monocytes by M-CSF.	21625498
Renal Insufficiency, Inflammation, Spinal Fractures	Altered Intercellular Communication	Postmenopausal White women with mild renal dysfunction were at increased risk of nonvertebral fracture; this association was at least partially explained by effects of renal dysfunction on chronic inflammation.	21625880
Inflammation	Altered Intercellular Communication	A left orbital biopsy showed xanthogranulomatous inflammation of the orbit.	21626164
Xanthogranulomatous inflammation	Altered Intercellular Communication	The left orbit was surgically debulked twice and histology revealed xanthogranulomatous inflammation, with the additional features of sclerosis, lymphoid aggregates and a prominent population of plasma cells.	21626164
Xanthogranulomatous inflammation	Altered Intercellular Communication	We propose that the overall disease is a novel variant of IgG4 sclerosing disease of the orbit and suggest that cases of histologically proven xanthogranulomatous inflammation should be stained for IgG4 if there is an accompanying plasma cell population.	21626164
Herpes Zoster Ophthalmicus, Inflammation	Altered Intercellular Communication	Herpes zoster ophthalmicus (HZO) occurs when inflammation spreads from the ganglion of Gasser to the ophthalmic branch of the trigeminal nerve.	21626168
Inflammation, Neoplasms	Altered Intercellular Communication	Nontraumatic brachial plexopathies may be caused by primary or secondary tumors, radiation or inflammation.	21627017
Inflammation, Demographics Domain, Diabetes Mellitus	Altered Intercellular Communication	It is well accepted that glycemic control in patients with diabetes mellitus (DM) is affected by systemic inflammation and oxidative stress.	21627458
Inflammation, Acute abscess	Altered Intercellular Communication	The biopsy sample was consistent with chronic non-specific inflammation in acute abscess.	21628820
Inflammation, Retinitis Pigmentosa, polychondritis, Cartilage	Altered Intercellular Communication	Relapsing polychondritis (RP) is a multiple system disease of unknown cause characterized by episodic inflammation of cartilage and potentially progressive degeneration of cartilaginous tissue.	21629081
Orbital Cellulitis	Altered Intercellular Communication	A total of 97 patients were admitted with a diagnosis of orbital inflammation/cellulitis, of whom 49 patients had clinical and/or radiographic evidence of orbital cellulitis.	21629136
Proteinuria, Toxic effect, Inflammatory disease of mucous membrane, Diarrhea, Bothered by Vomiting, Hypertension, CTCAE, Headache, Anorexia, Nausea, Dry skin, Weight decreased, Dermatitis acneiform, Pruritus, Fatigue	Altered Intercellular Communication	Toxicities observed were manageable; the most common treatment-related toxicities (>10% of patients) were fatigue, diarrhoea, anorexia, increase in aspartate aminotransferase and alanine aminotransferase, acneiform dermatitis, headache, mucosal inflammation, nausea, dry skin, vomiting, hypertension, pruritus, proteinuria and weight loss.	21629245
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Cholinesterase inhibitors are commonly prescribed to patients with Alzheimer's disease (AD) to enhance cholinergic neurotransmission.	21630031
Inflammation, Sarcoidosis	Altered Intercellular Communication	Sarcoidosis is a systemic granulomatous inflammation that occurs as a result of disturbed immune regulation in individuals exposed to certain environmental agents.	21630202
Necrotizing granulomatous inflammation, Granuloma	Altered Intercellular Communication	The existence of epithelioid histiocytes and/or giant cells that formed granulomas was used as a cytological diagnostic criterion for chronic granulomatous inflammation.	21630202
Necrotizing granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	A total of 31 out of the 38 patients were diagnosed as sarcoidosis with clinical, radiological and microbiological findings, after chronic granulomatous inflammation was considered by cytologic assessment.	21630202
Necrotizing granulomatous inflammation	Altered Intercellular Communication	We highlighted the adequacy criteria of cytological sampling and the encountered cytological findings of chronic granulomatous inflammation.	21630202
Mediastinal lymphadenopathy, Granulomatous inflammation, Lymphoma	Altered Intercellular Communication	EBUS-TBNA is a minimally invasive procedure which provides sufficient sample for definitive primary diagnosis and classification of malignant lymphoma and granulomatous inflammation in patients with mediastinal lymphadenopathy.	21630485
Angioedema, Communicable Diseases, Irritation - emotion, Airway structure	Altered Intercellular Communication	Long-term therapy with angiotensin-converting enzyme inhibitors could be associated with delayed angioedema, especially in patients with inflammation of airways caused by infection or chronic irritation.	21630523
Inflammation, Impaired mitochondrial function, Sarcopenia	Altered Intercellular Communication	The main mechanisms underlying sarcopenia have not been determined conclusively, but chronic inflammation, apoptosis, and impaired mitochondrial function are believed to play important roles.	21631380
Inflammation	Altered Intercellular Communication	Our findings for sTNF-R1 and sCD27, possible markers for inflammatory and B-cell stimulatory states, respectively, support a role for subclinical inflammation and chronic B-cell stimulation in lymphomagenesis.	21632552
Acute Coronary Syndrome, Dying Process, Inflammation	Altered Intercellular Communication	Fear of dying and inflammation following acute coronary syndrome.	21632602
Inflammation, Dying Process, Injury of cardiac valve	Altered Intercellular Communication	Intense distress and fear of dying and heightened inflammation may be related manifestations of an acute biobehavioural response to severe cardiac injury, and have implications for prognostically significant biological risk processes.	21632602
methyldopa, Inflammation	Altered Intercellular Communication	There is increasing evidence that inflammation and immune-mediated processes (complement activation) play an important role in age-related macular degeneration (AMD) pathogenesis.	21633121
methyldopa, Inflammation	Altered Intercellular Communication	A genetic variation in the gene encoding complement factor H (CFH) and plasma levels of C-reactive protein (CRP), a systemic marker of subclinical inflammation, have consistently been shown to be associated with an increased risk for AMD.	21633121
methyldopa, Inflammation	Altered Intercellular Communication	This study supports the hypothesis that inflammation and immune-mediated mechanisms are involved in the pathogenesis of AMD.	21633121
Inflammation	Altered Intercellular Communication	Caspase-8 (CASP8) involved in apoptosis plays an important role in mediating the normal regulation of cell proliferation, differentiation, inflammation, and homeostasis of multicellular organisms.	21633787
Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Inflammation within the abdominal aortic wall is generally considered a very significant ethiopathogenic factor in the development of abdominal aortic aneurysms.	21634132
Inflammation	Altered Intercellular Communication	Proinflammatory cytokines are important mediators of inflammation within the abdominal aortic wall.	21634132
Inflammation	Altered Intercellular Communication	Age-associated development of inflammation in Wistar rats: Effects of caloric restriction.	21635187
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Insulin resistance and type 2 Diabetes have been associated to a low grade of inflammation and their prevalence increase with ageing.	21635187
Inflammation, Hypothalamic structure	Altered Intercellular Communication	To analyse the development of inflammation in adipose tissue, liver, muscle and hypothalamus during ageing and the effects of caloric restriction.	21635187
Inflammation	Altered Intercellular Communication	These data indicate a role of adiposity in the development of inflammation and insulin resistance during ageing.	21635187
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, physiopathological	Altered Intercellular Communication	Discrepancies exist regarding the involvement of cellular inflammation and apoptosis in the muscle dysfunction of chronic obstructive pulmonary disease (COPD) patients with preserved body composition.	21636562
ARCN1 gene, Inflammation, physiopathological	Altered Intercellular Communication	In severe COPD patients with preserved body composition, while increased apoptotic nuclei seems to be a contributor to their muscle dysfunction, cellular inflammation does not.	21636562
Inflammation, Congenital Heart Defects, Lupus Erythematosus, Systemic	Altered Intercellular Communication	In stable SLE patients pericardial and valve abnormalities may be associated with markers of an ongoing inflammation.	21636627
Gastrointestinal inflammation	Altered Intercellular Communication	The MUC13 cell-surface mucin protects against intestinal inflammation by inhibiting epithelial cell apoptosis.	21636645
Inflammation, Squamous cell carcinoma	Altered Intercellular Communication	For pathology results, 1 patient had inflammation only, 1 had spindle cell cancer, and 15 had squamous cell cancer.	21637051
Inflammation, Ototoxicity, Demyelinating Diseases	Altered Intercellular Communication	Together, these results reveal that increased expression of the cystine/glutamate antiporter system x(c)- in MS provides a link between inflammation and excitotoxicity in demyelinating diseases.	21639880
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Calcium-containing crystals are quite common in primary OA and they worsen or may cause OA through induction of inflammation by neutrophils.	21640042
Inflammation	Altered Intercellular Communication	Colchicine inhibits urate-crystal and calcium-pyrophosphate (CPP) crystal induced inflammation and elastase, a matrix-metalloproteinase (MMP) that play a pivotal role in degenerative joint processes.	21640042
Inflammation, Hyperplasia, Atherosclerosis	Altered Intercellular Communication	Vascular lesions were categorized as showing intimal fibromuscular hyperplasia, atherosclerosis and/or inflammation.	21640617
Inflammation, Atheroma, Hyperplasia	Altered Intercellular Communication	Intramyocardial arteries showed primarily intimal fibromuscular hyperplasia and inflammation with no atheromas present.	21640617
Inflammation, Fibromuscular Dysplasia, Atherosclerosis	Altered Intercellular Communication	Lesions in the epicardial coronary arteries were composed of intimal fibromuscular hyperplasia, atherosclerosis and/or inflammation affecting one or more vascular layers (intima, media and adventitia).	21640617
Inflammation, Intimal proliferation	Altered Intercellular Communication	Both arteries and veins showed intimal hyperplasia and inflammation.	21640617
Inflammation, CAV1 gene, Vasculitis, CTCAE, Atherosclerosis	Altered Intercellular Communication	CAV is a pathologically multifaceted disorder that affects large and small epicardial coronary arteries of adults and children, with different types of lesions: intimal fibromuscular hyperplasia; atherosclerosis; and/or inflammation (vasculitis).	21640617
Inflammation, Venous Thromboembolism, vinyltriethoxysilane	Altered Intercellular Communication	Studies have established a relationship between inflammation and venous thromboembolism (VTE).	21641019
Inflammation, vinyltriethoxysilane	Altered Intercellular Communication	Though statins modulate inflammation, it is uncertain if they prevent VTE in heterogeneous populations.	21641019
Inflammation, Chronic sinusitis, Microbial Biofilms	Altered Intercellular Communication	Bacterial biofilms in chronic rhinosinusitis and their relationship with inflammation severity.	21641137
Inflammation, Heart failure, Bipolar Disorder	Altered Intercellular Communication	Depressive symptoms and inflammation in patients hospitalized for heart failure.	21641350
Inflammation, Heart failure, Bipolar Disorder	Altered Intercellular Communication	Depressive symptoms in patients with heart failure (HF) are common and might be associated with inflammation.	21641350
Inflammation, Bipolar Disorder	Altered Intercellular Communication	No studies have examined both the cross-sectional and prospective association between inflammation and depressive symptoms in patients with HF with adequate correction for disease severity.	21641350
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Data from 517 patients hospitalized for HF from the COACH study were analyzed on inflammation markers (IL-6 and CRP) and depressive symptoms (Center for Epidemiological Studies Depression-Scale).	21641350
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Structural equation modelling showed that the factor inflammation (including IL-6 and CRP) was associated with depressive symptoms (b = 0.18, P < .05) when left ventricular ejection fraction and plasma values brain natriuretic peptides were included in the model.	21641350
Inflammation, Bipolar Disorder	Altered Intercellular Communication	There is no clear relationship between inflammation at baseline and depressive symptoms during the 18 months of follow-up.	21641350
Inflammation, Villous atrophy	Altered Intercellular Communication	Many (54%) showed signs of inflammation in the biopsy, without villous atrophy.	21641886
Celiac Disease, Gastrointestinal symptom, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Overt coeliac disease is seldom found behind persistent AGA-positivity, but this characteristic is associated with mucosal inflammation and gastrointestinal symptoms at least in HLA-positive individuals.	21641886
Inflammation, Disease remission	Altered Intercellular Communication	Future clinical trials should emphasize the treatment of patients who have objective evidence of inflammation in addition to symptoms of active disease.	21642014
Cessation of life, Inflammation, Kidney Failure, Chronic	Altered Intercellular Communication	Inflammation and asymmetric dimethylarginine for predicting death and cardiovascular events in ESRD patients.	21642364
Kidney Failure, Chronic, Inflammation, Atherosclerosis, Endothelial dysfunction, Cessation of life	Altered Intercellular Communication	Endothelial dysfunction as assessed by asymmetric dimethylarginine (ADMA) and inflammation has been consistently linked to atherosclerosis, death, and cardiovascular (CV) events in ESRD patients.	21642364
Cessation of life, Inflammation, Kidney Failure, Chronic	Altered Intercellular Communication	With crude and multiple Cox regression analyses, an interaction was found between inflammation biomarkers and ADMA for explaining death and CV events in ESRD patients.	21642364
Cessation of life, Inflammation, Kidney Failure, Chronic	Altered Intercellular Communication	These data support the hypothesis that inflammation amplifies the risk of death and CV events associated with high ADMA levels in ESRD.	21642364
Inflammation, Bacterial Infections	Altered Intercellular Communication	The discrimination of bacterial infections from sterile inflammatory processes is of great importance in the management of inflammation.	21642882
Inflammation	Altered Intercellular Communication	On initial presentation, the patient complained of progressively worsening left-sided coxalgia without localized or generalized inflammation.	21645338
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Accordingly, PGRN-deficient mice have been demonstrated to develop enhanced inflammation and progressive neurodegeneration.	21645364
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Since neurodegeneration might be negatively impacted by chronic inflammation, the possible influence of PGRN defects on inflammatory pathways appears to be of great relevance for the understanding of neurodegeneration pathogenic processes in those patients.	21645364
vascular inflammations, Osage language	Altered Intercellular Communication	This suggests that OSA could activate vascular inflammation in CAD patients despite current best practice medications.	21646006
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Enhanced inflammation in epicardial fat in patients with coronary artery disease.	21646734
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Chronic inflammation in epicardial fat may influence the pathogenesis of coronary atherosclerosis.	21646734
Inflammation	Altered Intercellular Communication	CSS relapse may be linked to increased numbers of CD4+ T cells producing IL-25, which promotes Th2 inflammation, and to a decline in the Tr1 cell subpopulation resulting from lower IDO expression in monocytes.	21646795
Carcinoma of lung	Altered Intercellular Communication	Neutrophilic airways inflammation in lung cancer: the role of exhaled LTB-4 and IL-8.	21649887
Inflammation, Non-Small Cell Lung Carcinoma, Carcinoma of lung	Altered Intercellular Communication	The high concentrations of exhaled LTB-4 and IL-8 showed the presence of a neutrophilic inflammation in the airways of NSCLC patients and gave a further support to the inflammatory signalling in lung cancer.	21649887
Inflammation, Non-Small Cell Lung Carcinoma, Carcinoma of lung	Altered Intercellular Communication	The high concentrations of exhaled LTB-4 and IL-8 showed the presence of a neutrophilic inflammation in the airways of NSCLC patients and gave a further support to the inflammatory signalling in lung cancer.	21649887
Coughing, Airway structure	Altered Intercellular Communication	Serum LDH in chronic cough: a potential marker of airway inflammation.	21651741
Airway structure, Chronic cough	Altered Intercellular Communication	This rise is likely to be due to airway inflammation known to be associated with chronic cough.	21651741
Inflammation	Altered Intercellular Communication	Exposure to particulate matter (PM) may induce inflammation and oxidative stress in the airways.	21651749
Inflammatory abnormality of the eye	Altered Intercellular Communication	QuantiFERON-TB gold cut-off value: implications for the management of tuberculosis-related ocular inflammation.	21652022
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ninety-six consecutive patients presenting with ocular inflammation between January and October 2007 were tested using QuantiFERON-TB Gold.	21652022
Inflammatory abnormality of the eye	Altered Intercellular Communication	Treatment was considered effective at the end of follow-up, in cases of no or a 2-point decrease of ocular inflammation (SUN criteria) and systemic corticosteroids stopped or tapered to 10 mg/day.	21652022
Inflammatory abnormality of the eye, Panuveitis, Scleritis, Uveitis	Altered Intercellular Communication	Types of ocular inflammation included scleritis (n = 7), panuveitis (n = 34), and posterior (n = 15), intermediate (n = 14), and anterior uveitis (n = 15).	21652022
Intraocular inflammation, Complication Aspects	Altered Intercellular Communication	A total of 126 patients (156 eyes) were evaluated for presence of CME, visual acuity, intraocular pressure, degree of intraocular inflammation, and the presence of ocular complications.	21652023
Communicable Diseases, Inflammation	Altered Intercellular Communication	Postoperative follow-up showed that the simultaneous everting sutures caused no problems with the cultivated oral mucosal epithelial sheet, and there were no severe complications such as infection or inflammation.	21652025
Myocarditis, CTCAE 5.0, Myocardium	Altered Intercellular Communication	Myocarditis, a general inflammatory condition of the heart muscle, can result from a variety of etiologies, the most common being viral.	21652168
Inflammation	Altered Intercellular Communication	Potential explanations for the increased risk of AF in CD include chronic inflammation and shared risk factors, but ascertainment bias may also have contributed.	21653560
Inflammation, Atherosclerosis	Altered Intercellular Communication	Dietary micronutrient intakes are associated with markers of inflammation but not with markers of subclinical atherosclerosis.	21653577
Inflammation, Atherosclerosis	Altered Intercellular Communication	Few studies have examined associations of dietary micronutrients with markers of inflammation and subclinical atherosclerosis.	21653577
Inflammation, Diabetes Mellitus, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	Micronutrient intakes and markers of inflammation and subclinical atherosclerosis were studied in 5,181 participants from the Multi-Ethnic Study of Atherosclerosis who were aged 45-84 y and free of diabetes and cardiovascular disease.	21653577
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	Accelerated aging in the tumor microenvironment: connecting aging, inflammation and cancer metabolism with personalized medicine.	21654190
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	Here, we discuss how ROS signaling, NFkB- and HIF1-activation in the tumor microenvironment induces a form of "accelerated aging," which leads to stromal inflammation and changes in cancer cell metabolism.	21654190
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	Thus, we present a unified model where aging (ROS), inflammation (NFkB) and cancer metabolism (HIF1), act as co-conspirators to drive autophagy ("self-eating") in the tumor stroma.	21654190
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	These findings have important new implications for personalized cancer medicine, as they link aging, inflammation and cancer metabolism with novel strategies for more effective cancer diagnostics and therapeutics.	21654190
Acute Lung Injury, Pneumonitis	Altered Intercellular Communication	EPA/GLA has anti-inflammatory benefits, as evidenced by its association with reduction in pulmonary inflammation, improvement in oxygenation and improved clinical outcomes in patients with severe forms of acute lung injury.	21658240
Cholangiocarcinoma, Primary malignant neoplasm, Liver carcinoma, FAM126A gene, Abdominal Infection, Liver Cirrhosis	Altered Intercellular Communication	Overall, the predominant risk factor was hepatocellular carcinoma (HCC) (52.5%), followed by liver cirrhosis without cancer (9.3%), abdominal infection/inflammation (9.3%), cholangiocarcinoma (8.2%), and abdominal intervention (7.7%).	21658275
Liver Abscess, Pancreatitis, Tuberculosis, Splenic abscess, Omphalitis of the newborn, Cholecystitis, Cholangitis	Altered Intercellular Communication	A variety of abdominal infections/inflammations were also found including liver abscess, splenic abscess, cholangitis, cholecystitis, pancreatitis, omphalitis, and abdominal tuberculosis.	21658275
Chlamydia trachomatis, Inflammatory abnormality of the eye	Altered Intercellular Communication	Molecular approach by PCR is the best method to detect the presence of Chlamydia trachomatis and to define the true agent of ocular bacterial inflammation.	21658303
methyldopa, Inflammation	Altered Intercellular Communication	In atrophic AMD, drugs attempt to spare the photoreceptors and the retinal pigment epithelium to prevent the oxidative damages or to suppress the inflammation process.	21658792
Inflammation	Altered Intercellular Communication	Mortality in long-term hemodialysis patients is high, mostly attributed to cardiovascular events, and may be related to chronic inflammation.	21658827
Cessation of life, Inflammation	Altered Intercellular Communication	Higher dietary omega-6 to omega-3 ratio appears to be associated with both worsening inflammation over time and a trend toward higher death risk in hemodialysis patients.	21658827
Inflammation, Anemia, Hematologic Neoplasms	Altered Intercellular Communication	Anemia etiologies included iron deficiency anemia at 25.3%, anemia of chronic inflammation at 9.8%, and hematologic malignancy in 7.5%.	21659341
Inflammation, Bone structure of calcaneum	Altered Intercellular Communication	Infected and healthy cancellous bone of the calcaneus is removed to eradicate all possible foci that maintain inflammation.	21659847
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Patients with chronic obstructive pulmonary disease (COPD) are prone to clinical exacerbations that are associated with increased airway inflammation, a potent pro-thrombotic stimulus.	21660493
Inflammation, Blood coagulation, Exacerbation	Altered Intercellular Communication	Elevation of IL-6, vWF, D-D and F1+2 levels during COPD exacerbations implies a strict association between acute inflammation, endothelial activation and clotting initiation.	21660493
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	The markers of inflammation and (apo)lipoproteins are associated with coronary artery disease (CAD).	21660913
Inflammation, Hypotension, CTCAE, Abdominal rebound tenderness, Anemia, Tachycardia by ECG Finding	Altered Intercellular Communication	A 47-year old man presented with abdominal rebound tenderness, hypotension and tachycardia, anemia, and elevated markers of inflammation.	21661368
Inflammation, Hemorrhage, granulocyte, Necrosis	Altered Intercellular Communication	Histologic specimen showed full-thickness nonspecific inflammation of the intestinal wall with granulocytic infiltration, hemorrhage and necrosis.	21661368
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Histological analysis of excised appendix showed inflammation but without signs typical for vasculitis.	21661371
Inflammation, polyps, Meckel Diverticulum, Neoplasms, Ulcer, Angiodysplasia, Crohn Disease	Altered Intercellular Communication	These lesions were small-intestinal ulcers, Crohn's disease, chronic inflammation, Meckel's diverticulae, angiodysplasia, polyps, ulcerative lipoma and tumor.	21661416
helium, Inflammation, Hepatic Encephalopathy	Altered Intercellular Communication	It has been suggested that the presence of inflammation may accentuate the neuropsychologic alterations in hepatic encephalopathy (HE).	21661419
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	There is an inflammatory response in the presence of cirrhosis and HE; and IL-18 may play a role in the perpetuation of chronic inflammation.	21661419
Communicable Diseases, Inflammation	Altered Intercellular Communication	No adverse events, such as infection, persistent inflammation, or abutment screw loosening, occurred.	21661660
Intraocular inflammation	Altered Intercellular Communication	Although the pathogenesis of bone formation in choroidal osteoma remains uncertain, intraocular inflammation might be one cause.	21661667
Inflammation, Fever, CTCAE, Vasospasm	Altered Intercellular Communication	Further studies are needed to determine if treatments targeting fever and inflammation may be effective in reducing the incidence of vasospasm following severe TBI.	21663415
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	The role of combined assessment of defense against oxidative stress and inflammation in the evaluation of peripheral arterial disease.	21663591
Inflammation	Altered Intercellular Communication	High sensitivity C-reactive protein (hsCRP) is an acute phase reactant and a sensitive marker of inflammation.	21663637
Airway structure	Altered Intercellular Communication	The epithelial senescence was accompanied by p38 MAPK-dependent airway inflammation.	21663649
Airway structure, Inflammation, ARCN1 gene	Altered Intercellular Communication	Senescence of airway epithelial cells impairs repair processes and exacerbates p38 MAPK-dependent inflammation after airway injury, and it may contribute to the pathogenesis of COPD.	21663649
Communicable Diseases, Inflammation, Prostate carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Recent epidemiologic, genetic, and molecular studies suggest infection and inflammation initiate certain cancers, including cancers of the prostate.	21663671
Inflammation, Abdominal Pain	Altered Intercellular Communication	Vaginal discharge, cervical inflammation and abdominal pain differed significantly in relation to age.	21663876
Inflammation, Paratuberculosis	Altered Intercellular Communication	paratuberculosis (Map) is the causative agent of Johne's disease, a chronic inflammation of ruminants' intestine.	21664191
Inflammation, Unipolar Depression, Coronary heart disease	Altered Intercellular Communication	Inflammation and treatment response to sertraline in patients with coronary heart disease and comorbid major depression.	21665007
Inflammation, Depressed mood, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Studies in depressed patients without CHD suggest that elevated markers of inflammation predict poor response to treatment.	21665007
Inflammation, Unipolar Depression, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	We therefore studied the relationship between pretreatment markers of inflammation and treatment response in patients with CHD and major depression.	21665007
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Similarly, depression remitters (BDI-II <=8 at post-treatment) did not differ from non-remitters on the three baseline inflammation markers.	21665007
Inflammation, Pancreatic carcinoma	Altered Intercellular Communication	Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence.	21665147
Inflammation, Neoplasms	Altered Intercellular Communication	The pre-operative biopsy taken after 3 months showed chronic inflammation and cytomegalovirus inclusions, but no tumour.	21665860
Keratitis, "Moorens ulcer	Altered Intercellular Communication	To evaluate the extent of corneal inflammation and the response to treatment in patients with Mooren's ulcer, by in vivo confocal microscopy (IVCM).	21666242
Autoimmune Hypophysitis, Autoimmune endocrine disease, Lymphocytic infiltration	Altered Intercellular Communication	Recurrent autoimmune hypophysitis is a rare autoimmune endocrine disease involving lymphocytic infiltration and chronic pituitary inflammation.	21666339
Inflammation, Periprosthetic Fractures	Altered Intercellular Communication	Histological analysis of periprosthetic tissue in all 3 cases identified characteristic features such as perivascular lymphocytic aggregates and chronic inflammation consistent with aseptic lymphocytic vasculitis-associated lesions (ALVAL).	21667724
Wounds and Injuries	Altered Intercellular Communication	Predisposing factors are: traumas, inflammatory conditions and biomechanics alterations.	21669155
Colorectal Carcinoma, Gastrointestinal inflammation	Altered Intercellular Communication	We had a particular interest in patients suffering from intestinal inflammation as this may stimulate endogenous NOC formation, and consequently predispose to CRC risk.	21669488
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Irritable Bowel Syndrome	Altered Intercellular Communication	Inflammatory bowel disease (IBD) patients diagnosed with ulcerative colitis and irritable bowel syndrome patients without inflammation, serving as controls, were therefore recruited.	21669488
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	However, fecal NOC levels were slightly but not significantly increased in IBD patients, suggesting that inflammation did not strongly stimulate NOC formation.	21669488
Rheumatoid Arthritis, bone destruction, Autoimmune reaction	Altered Intercellular Communication	Collectively, our data suggest that systemic IL-23 exposure induces the expansion of a myeloid lineage osteoclast precursor, and targeting IL-23 pathway may combat inflammation-driven bone destruction as observed in rheumatoid arthritis and other autoimmune arthritides.	21670317
Inflammation, Albuminuria, Demographics Domain	Altered Intercellular Communication	Rosuvastatin administration reduced albuminuria, serum cystatin C levels, and inflammation, and improved lipid profiles, regardless of the presence or absence of DM, and the degree of the eGFR.	21670545
Inflammation, Cerebral Infarction	Altered Intercellular Communication	High serum antibody titers to P. gingivalis SU63 could be a predictor of cerebral infarction in Japanese men independent of traditional risk factors and inflammation.	21670558
Celiac Disease, Gastritis, Esophagitis, Inflammatory Bowel Diseases	Altered Intercellular Communication	Few Foxp3(+) cells were found in controls and inflammatory conditions (oesophagitis, gastritis, coeliac disease, inflammatory bowel disease); in preneoplastic and neoplastic conditions the number of Foxp3(+) cells was significatively increased.	21670722
Inflammation, Carcinogenesis	Altered Intercellular Communication	Neutrophil gelatinase-associated lipocalin (NGAL) is multi-functional protein, released from activated neutrophils, with roles in inflammation, immune function, and carcinogenesis.	21670771
Inflammation, pars defect	Altered Intercellular Communication	To evaluate the inflammation around the pars defects, short time inversion recovery (STIR) MRI was performed along with the sagittal section.	21671077
Inflammation, pars defect	Altered Intercellular Communication	Inflammation (i.e., fluid collection) was observed in all 12 pars defects in six subjects at the pseudoarthrotic pars defects.	21671077
Inflammation, pars defect, Facet joint structure	Altered Intercellular Communication	The present study showed that inflammation was always present at the pars defects and in some cases at the adjoining facet joints.	21671077
Inflammation, Facet joint structure	Altered Intercellular Communication	Thus, it is not difficult to understand how, during sports activity, inflammation may first occur at the pseudoarthrotic site and then spread to the adjoining facet joints.	21671077
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Abstract Background: Chronic inflammation and oxidative stress are associated with the development of metabolic syndrome (MetS).	21671781
Inflammation	Altered Intercellular Communication	We hypothesized that cardiac resynchronization therapy (CRT) improves cardiac sympathetic nervous dysfunction and systemic inflammation.	21671958
Inflammation	Altered Intercellular Communication	Our results demonstrated that cardiac sympathetic nervous dysfunction and systemic inflammation were improved in responder HF patients to CRT.	21671958
Inflammation	Altered Intercellular Communication	Furthermore, the reduction in systemic inflammation was associated with the improvement in cardiac sympathetic nervous dysfunction.	21671958
Inflammation	Altered Intercellular Communication	The sera were analysed with respect to biochemical parameters of systemic inflammation and liver function and to the presence of antibodies to nuclear antigens (ANA), mitochondria (AMA) and smooth muscle (SMA).	21671974
Dermatitis	Altered Intercellular Communication	These proteins were upregulated in cell populations that are critically involved in the pathogenesis of chronic skin inflammation, such as keratinocytes, macrophages in deep dermis and cells at the perivascular/endothelial area.	21672030
Psoriasis, Dermatitis	Altered Intercellular Communication	We conclude that interactions between TL1A and its two receptors may be involved in the pathogenesis of chronic skin inflammation that takes place in psoriasis.	21672030
Inflammation	Altered Intercellular Communication	Stress and inflammation reduce brain-derived neurotrophic factor expression in first-episode psychosis: a pathway to smaller hippocampal volume.	21672499
Inflammation Mediators, Traumatic injury	Altered Intercellular Communication	A linear regression analysis in patients showed that a history of childhood trauma and high levels of recent stressors predicted lower BDNF expression through an inflammation-mediated pathway (adjusted R(2) = 0.23, P = .009).	21672499
Data types - Address, Dermatitis	Altered Intercellular Communication	Skin colonization with S aureus is prevalent in children and adults with AD, and can aggravate skin inflammation.	21673210
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Glucokinase regulatory protein genetic variant interacts with omega-3 PUFA to influence insulin resistance and inflammation in metabolic syndrome.	21674002
Inflammation, Sacroiliac joint structure, Peripheral, Spondylitis	Altered Intercellular Communication	Ankylosing spondylitis (AS) is a chronic inflammation of the sacroiliac joints, spine and peripheral joints.	21674042
Granulomatous inflammation, Vasculitis, CTCAE, Necrosis	Altered Intercellular Communication	Cardinal histologic features include a necrotizing vasculitis involving small vessels, extensive "geographic" necrosis, and granulomatous inflammation.	21674414
Inflammation, Neoplasms	Altered Intercellular Communication	Substantial evidence indicates that inflammation is a critical component of tumor progression.	21674477
Inflammation, Necrosis, hydrocortisone, Insemination, Artificial, Homologous, Interface hepatitis	Altered Intercellular Communication	Interface hepatitis, focal necrosis, and portal inflammation were present in all evaluated cases, but were more severe in AIH (P < 0.05) than DILI (HC).	21674554
Inflammation, Canalicular cholestasis, Insemination, Artificial, Homologous	Altered Intercellular Communication	A model combining portal inflammation, portal plasma cells, intra-acinar lymphocytes and eosinophils, rosette formation, and canalicular cholestasis yielded an area under the receiver operating characteristic curve (AUROC) of 0.90 in predicting DILI (HC) versus AIH.	21674554
Inflammation, Insemination, Artificial, Homologous	Altered Intercellular Communication	All Ishak inflammation scores were more severe in AIH than DILI (CS) (P <= 0.05).	21674554
Inflammation, Fibrosis Assessment, Cholestasis, Insemination, Artificial, Homologous	Altered Intercellular Communication	The combination of portal inflammation, fibrosis, portal neutrophils and plasma cells, and intracellular (hepatocellular) cholestasis yielded an AUC of 0.91 in predicting DILI (CS) versus AIH.	21674554
Inflammation, Erythema	Altered Intercellular Communication	Colonoscopy demonstrated diffuse inflammation with erythema, friability, and shallow ulcerations in the rectum and colon.	21675504
Inflammation	Altered Intercellular Communication	BAC causes similar X-ray changes to COP and inflammation accompanying BAC can also respond to corticosteroids, which may lead to delay in the diagnosis of BAC associated with COP.	21675931
Inflammation	Altered Intercellular Communication	Presence of aortic inflammation was ascertained through linkage to a nationwide pathology registry.	21676237
Inflammation, Connective Tissue Diseases, Diabetes Mellitus	Altered Intercellular Communication	Predictors of inflammation included connective tissue disease, diabetes, advanced age, and aortic valve pathology.	21676237
Inflammation, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	Chronic Kidney Disease (CKD) patients present high levels of electronegative LDL (LDL-) that can modulate the expression of molecules involved in inflammation and it is closely linked to atherosclerosis.	21676364
Inflammation, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	The association between LDL(-) and inflammation and the lower levels of anti-LDL(-) autoantibodies are important risk factors related to atherosclerosis in CKD.	21676364
ARCN1 gene, Inflammation	Altered Intercellular Communication	Cigarette smoke is the main cause of inflammation in COPD.	21676518
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is a critical contributing factor to the development and progression of atherosclerosis.	21676590
Communicable Diseases, Osteonecrosis of Jaw, Inflammation, Necrosis	Altered Intercellular Communication	The predilection for mandibular molar and premolar regions, and the infectious conditions that often precede the onset of ONJ support recent pathogenesis theories stating that local inflammation and associated pH-changes may trigger the release and activation of nitrogen-containing bisphosphonates ultimately resulting in necrosis.	21676622
Masked Hypertension, Inflammation, ciliary vesicle	Altered Intercellular Communication	Masked-hypertension was identified in 58% of African Americans which suggests that a masking phenomenon may exist in a sub-group of prehypertensives who also seem to have a diminished endothelial function that could be mediated by an elevated subclinical inflammation leading to the increased CV disease.	21677701
Primary malignant neoplasm, Chronic disease, Obesity	Altered Intercellular Communication	Obesity is associated with a variety of chronic diseases, including cancer, which may partly be explained by its influence on sex steroid hormone concentrations.	21678033
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	UC was also subgrouped according to the severity of inflammation.	21678108
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In contrast, the mucosal up-regulation of MMP-9 correlated with the severity of inflammation in UC.	21678108
ARCN1 gene, Inflammation	Altered Intercellular Communication	Relation between physical capacity, nutritional status and systemic inflammation in COPD.	21679348
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Fat-free mass, Weight decreased	Altered Intercellular Communication	Decreased physical capacity, weight loss, fat-free mass depletion and systemic inflammation are frequently observed in patients with chronic obstructive pulmonary disease (COPD).	21679348
ARCN1 gene, Inflammation	Altered Intercellular Communication	Our aim was to examine relations between physical capacity, nutritional status, systemic inflammation and disease severity in COPD.	21679348
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Physical capacity in chronic obstructive pulmonary disease is related to lung function, body composition and systemic inflammation.	21679348
Inflammation, Atherosclerosis	Altered Intercellular Communication	Transforming growth factor-b1 (TGF-b1) is a multifunctional cytokine involved in inflammation and pathogenesis of atherosclerosis.	21679448
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide (NO) production is increased in asthma and reflects the degree of airway inflammation.	21679473
Inflammation, Nasopharyngeal carcinoma	Altered Intercellular Communication	The patients were divided into two groups depending on the pathological results: nasopharyngeal carcinoma (NPC) and lymphoid hyperplasia/chronic inflammation (LH).	21679514
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	Because fluorodeoxyglucose positron emission tomography (FDG-PET) imaging provides a noninvasive index of inflammation, we sought to assess whether FDG uptake in the aortic valve (AV) is increased in aortic stenosis (AS).	21679852
Inflammation, Late stage	Altered Intercellular Communication	This study supports the hypothesis that AS is an inflammatory condition and suggests that inflammation may be reduced in late-stage disease.	21679852
Inflammation, Late stage	Altered Intercellular Communication	This study supports the hypothesis that AS is an inflammatory condition and suggests that inflammation may be reduced in late-stage disease.	21679852
Inflammatory abnormality of the eye, Primary anterior uveitis, Uveitis	Altered Intercellular Communication	Patients with primary anterior uveitis presenting to 1 of 4 academic ocular inflammation subspecialty practices achieving remission of the primary episode within 90 days of initial uveitis diagnosis.	21680024
Inflammation, Tumor necrosis, Retinoblastoma	Altered Intercellular Communication	Histopathology of the enucleated eye revealed diffuse inflammation and tumor necrosis but with absence of malignant retinoblastoma cells.	21680213
Inflammation, NCI CTEP SDC Retinoblastoma Sub-Category Terminology	Altered Intercellular Communication	The patient is presumed to have had retinoblastoma that underwent autoinfarction, leading to secondary inflammation.	21680213
Inflammation, Vascular calcification, Plaque, Atherosclerotic	Altered Intercellular Communication	Correlation of inflammation assessed by 18F-FDG PET, active mineral deposition assessed by 18F-fluoride PET, and vascular calcification in atherosclerotic plaque: a dual-tracer PET/CT study.	21680686
Inflammation, Calcinosis, Plaque, Atherosclerotic	Altered Intercellular Communication	Formation and progression of atherosclerotic plaque is a dynamic and complex process involving various pathophysiologic steps including inflammation and calcification.	21680686
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Exacerbations of chronic obstructive pulmonary disease (COPD) are heterogeneous with respect to inflammation and etiology.	21680942
ARCN1 gene, Exacerbation, Airway structure	Altered Intercellular Communication	Investigate biomarker expression in COPD exacerbations to identify biologic clusters and determine biomarkers that recognize clinical COPD exacerbation phenotypes, namely those associated with bacteria, viruses, or eosinophilic airway inflammation.	21680942
Hepatic, Inflammation, Cholestasis, Cholestanes	Altered Intercellular Communication	CK-7 expression was evaluated as a marker of cholestasis (cholestatic pattern) and inflammation (hepatitic pattern).	21681009
Airway structure, Bronchiolitis	Altered Intercellular Communication	To evaluate the existence of airway inflammation and characteristic of RSV bronchiolitis, we analyzed and compared the concentrations of eosinophilic cationic protein (ECP) in nasal fluid and plasma.	21681019
Airway structure, Infancy	Altered Intercellular Communication	The monitoring of ECP concentration in nasal fluid may be useful for evaluating leukocyte (including eosinophils and neutrophils)-mediated airway inflammation during infancy and its severity.	21681019
Inflammation, Neoplasms, Infection, Anemia, Inflammatory disorder, Thrombocytosis	Altered Intercellular Communication	Thrombocytosis was not a non-specific marker of inflammation, because uncomplicated infections and most admission causes were not associated with thrombocytosis, except for inflammatory rheumatic diseases (6% versus 1%), along with anemia (9.4% versus 2.5%) and tumor comorbidity (25% versus 14%).	21681080
Inflammation, Thrombocytosis	Altered Intercellular Communication	Thrombocytosis is not a simple marker of inflammation.	21681080
Inflammation, Microscopic hematuria, physiopathological	Altered Intercellular Communication	Laboratory data revealed signs of inflammation, glomerular dysfunction with microhaematuria, and positive myeloperoxidase-antineutrophil cytoplasmic antibodies.	21681367
Acute hepatopathy, Hepatitis	Altered Intercellular Communication	SNMC can be used safely and be useful for patients with difficult-to-diagnose acute liver disease as an 'initial' treatment tool to improve liver inflammation before starting disease-specific treatments.	21681505
primary infection nos, Pneumocystis jiroveci, Upper Respiratory Infections	Altered Intercellular Communication	Primary infection with Pneumocystis jirovecii in small children may cause inflammation of the respiratory tract which requires hospitalization.	21682093
Virus Diseases	Altered Intercellular Communication	The obtained results confirm that primary P. jirovecii infections may occur in the form of acute respiratory tract inflammations suggesting a viral infection.	21682093
Communicable Diseases, Inflammation	Altered Intercellular Communication	Two distal screws loosened (revised with new distal screws), and one early inflammation and one late infection occurred (revised to arthrodesis).	21682612
Sepsis, Communicable Diseases, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	Sepsis is a complex immunological response to infection characterized by early hyper-inflammation followed by severe and protracted immunosuppression, suggesting that a multi-marker approach has the greatest clinical utility for early detection, within a clinical environment focused on Systemic Inflammatory Response Syndrome (SIRS) differentiation.	21682927
Sepsis, Inflammation, Traumatic injury	Altered Intercellular Communication	Thus, the primary objective was to apply these gene expression biomarkers to distinguish patients with sepsis from those who had undergone major open surgery and had clinical outcomes consistent with systemic inflammation due to physical trauma and wound healing.	21682927
hydrocortisone, Inflammation	Altered Intercellular Communication	Quantitative PCR results suggest the capacity for this test to differentiate severe systemic inflammation from HC is 92%.	21682927
Abnormal cornea morphology, Conjunctivitis	Altered Intercellular Communication	Relief of symptoms, conjunctival inflammation, corneal epithelial abnormalities, and visual acuity were compared before and after surgeries as outcome measures.	21683334
Conjunctivitis	Altered Intercellular Communication	Conjunctival inflammation was reduced markedly in 19 eyes (86.4%).	21683334
Data types - Address	Altered Intercellular Communication	These novel findings suggest that distinct Ab oligomers induce impairment of cholinergic neurotransmission in AD pathogenesis.	21683475
Inflammation, Xerostomia, Chronic Kidney Diseases	Altered Intercellular Communication	The aim of this observational study was to investigate the relationship between DNA damage in minor accessory salivary glands, hyposalivation, and inflammation in patients with chronic kidney disease (CKD).	21684780
Inflammation, Hepatobiliary Disorder, Liver Cirrhosis	Altered Intercellular Communication	In chronic hepatitis C, selective expansion of peripheral T-regs in patients with normal aminotransferases and advanced disease suggests that, though a continual low level inflammation does not prevent liver disease progression, once cirrhosis has developed it may represent an attempt to prevent immuno-mediated decompensation.	21684822
Inflammation, Pterygia	Altered Intercellular Communication	The high prediction accuracy based on phospho- and total protein levels and phospho/total ratio of ERK1/2, p38, JNK, and IkB-a suggests these molecules as potential biomarkers of inflammation in pterygia.	21685342
Inflammation, hepcidin	Altered Intercellular Communication	The transcriptional mechanism of hepcidin in hepatocytes during inflammation is mediated via the IL-6/STAT3 pathway.	21685415
Inflammation, Depression, CTCAE, Coronary heart disease	Altered Intercellular Communication	Some studies have reported that depression is associated with higher levels of C-reactive protein (CRP) a marker of systemic inflammation that has been shown consistently to predict coronary heart disease risk.	21685519
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation, the key regulator of CRP synthesis, plays a pivotal role in atherothrombotic cardiovascular disease.	21685519
Inflammation	Altered Intercellular Communication	Positive findings of CD including active inflammation, stricturing, and penetrating disease were more frequent in MREs ordered to evaluate obstructive symptoms (87.5%) compared other indications (58.1%, p = 0.001).	21688128
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Results suggest that MQ benefits cancer patients' self-reported CF, QOL, and inflammation.	21688163
Inflammation, MZB1 gene	Altered Intercellular Communication	MEDA-7 is a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes.	21688198
Inflammation, MZB1 gene	Altered Intercellular Communication	MEDA-7 is a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes.	21688198
Asthmatic Airway Remodeling	Altered Intercellular Communication	Eosinophils play a pivotal role in asthmatic airway inflammation.	21690039
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	Rhinovirus (RV)-induced chronic obstructive pulmonary disease (COPD) exacerbations exhibit TH(2)-like inflammation.	21691053
Retinal Vein Occlusion, Inflammation	Altered Intercellular Communication	All three patients developed a branch retinal vein occlusion at the site of inflammation.	21691257
Intraocular inflammation, Inflammation, Choroiditis, Communicable Diseases, Retinitis, Vitritis, Retinal Vasculitis, Systemic disease	Altered Intercellular Communication	These patients had no other evidence of intraocular inflammation, including vitritis, retinitis, retinal vasculitis, or choroiditis, nor was there any systemic disorder associated with inflammation, infection, or coagulation identified.	21691257
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	IDO expression in LL-SCC may aid immune escape and chronic inflammation to promote cancer progression.	21692032
Inflammation, Fatigue	Altered Intercellular Communication	The associations of adiposity, physical activity and inflammation with fatigue in older adults.	21693185
Alveolar Septum, Interstitial inflammation	Altered Intercellular Communication	Routine examination of a lung biopsy, 4 months after transplantation, showed nonspecific, diffuse interstitial inflammation with alveolar septal fibrosis.	21693291
Inflammation, Atrophic	Altered Intercellular Communication	Ghrelin is a hormone produced in the oxyntic glands of the stomach, and under conditions of chronic inflammation and atrophy, serum ghrelin concentrations decrease.	21693726
Inflammation, Atrophic	Altered Intercellular Communication	Ghrelin is a hormone produced in the oxyntic glands of the stomach, and under conditions of chronic inflammation and atrophy, serum ghrelin concentrations decrease.	21693726
Inflammation, TSC22D3 gene, Neoplasms	Altered Intercellular Communication	Glucocorticoid-induced TNFR family-related Receptor (GITR)-mediated inflammation of tumor infiltrating leucocytes (TILs) in the tumor microenvironment might play a role during the multistep carcinogenetic process as either tumor promoting factor according to an inflammatory microenvironment or as a feature of anti-tumor activity.	21694467
Inflammation, Microorganism	Altered Intercellular Communication	We reviewed the clinical findings, therapeutic interventions, and visual outcomes of patients with suppurative scleral inflammation without preceding microbial keratitis who had microorganisms isolated from scleral scrapings.	21694595
Inflammation, Scleritis, Scedosporium, Pseudomonas aeruginosa	Altered Intercellular Communication	Of 349 patients with scleritis diagnosed from 1999 to 2009, 6 adults (1.7%) presented with suppurative inflammation of the anterior sclera due to Pseudomonas aeruginosa (2), Streptococcus pneumoniae (2), Staphylococcus aureus (1), and Scedosporium apiospermum/Pseudallescheria boydii (1).	21694595
Inflammation, S100A4 protein, human	Altered Intercellular Communication	Looking for a potential biomarker of malignant transformation in the setting of chronic inflammation we studied the levels of prostaglandin E2 (PGE(2)), as well as peptide growth factors [epidermal growth factor (EGF) and transforming growth factor a (TGFa)], harbingers of injury and repair, in gastric juice aspirated at endoscopy from patients with CAG, CAG/IM, AdCa, and controls.	21695403
Inflammation, Progranulins, Frontotemporal Lobar Degeneration	Altered Intercellular Communication	FTLD has recently been shown to be associated with mutations in GRN gene, coding for progranulin, a multifunctional secreted glycoprotein involved in cell cycle, inflammation and tissue repair.	21695656
Inflammation, Dyslipidemias	Altered Intercellular Communication	Brain volume reductions have also been associated with chronic low-grade inflammation and dyslipidaemia.	21695767
Inflammation, Dyslipidemias	Altered Intercellular Communication	This study investigated the relationships among T2DM, gender, inflammation, dyslipidaemia, and hippocampal volumes.	21695767
Inflammation, Anemia, Sickle Cell, Amyloidosis	Altered Intercellular Communication	After elimination of other causes, it was concluded that amyloidosis was the result of recurrent acute inflammation secondary to sickle cell disease.	21695882
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	sCD40L was higher in smokers and negatively associated with lung function and positively associated with total cholesterol and markers of inflammation, but not with other established cardiovascular disease (CVD) risk factors.	21696538
Inflammation, Diabetes Mellitus, Insulin-Dependent, Albuminuria, Endothelial dysfunction	Altered Intercellular Communication	YKL-40 is involved in inflammation and endothelial dysfunction, and is increased in patients with type 1 diabetes, with an independent association between increasing YKL-40 levels and increasing levels of albuminuria.	21696606
Traumatic injury	Altered Intercellular Communication	The prior trauma to the nail also suggests that posttraumatic inflammation may play a role in SUM development.	21696688
Narcolepsy, daytime sleepiness, Cataplexy, Disease	Altered Intercellular Communication	Narcolepsy with cataplexy (NC) is a disabling disorder characterized by excessive daytime sleepiness and abnormal rapid eye movement (REM) sleep manifestations, due to a deficient hypocretin/orexin neurotransmission.	21697009
Inflammatory abnormality of the eye	Altered Intercellular Communication	Treatment with topical antiglaucoma medications for longer than 1 year may start to induce ocular surface inflammation.	21697136
Tears body substance, Glaucoma, Primary Open Angle	Altered Intercellular Communication	Proteomic profiling of inflammatory signaling molecules in the tears of patients on chronic glaucoma medication.	21697136
Inflammation, Atherosclerosis	Altered Intercellular Communication	Furthermore, our data suggest an intimate connection between atherosclerosis and the innate immune system and inflammation via TLR signaling in lower risk individuals.	21698167
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Decreased levels of this protease correlate with the severity of the inflammation in patients with inflammatory bowel disease.	21698174
Refractory Cytopenia of Childhood, Aggressive course, Epithelioid hemangioendothelioma, Renal Cell Carcinoma Pathway	Altered Intercellular Communication	Epithelioid angiosarcomas (EAS) of kidney are rare and aggressive tumors with noncharacteristic imaging features that overlap with those of inflammatory conditions and renal cell carcinoma (RCC).	21698784
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Kidney Failure, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD) associated with type 2 diabetes is the leading cause of kidney failure, with both inflammation and oxidative stress contributing to disease progression.	21699484
Inflammation, Kidney Diseases, Retinal Diseases, Neuropathy	Altered Intercellular Communication	PAD; SMI; ED; 24-hour blood pressure Holter; lipid profile; insulin resistance; testosterone; chronic inflammation; nephropathy; retinopathy; neuropathy.	21699670
Autoimmune Diseases, Inflammation, Kabardian language	Altered Intercellular Communication	We conclude that autoimmunity and inflammation may be involved in the pathogenesis of KBD, in particular in the advanced stage.	21699943
Mediastinal lymphadenopathy, Granuloma, Myocarditis	Altered Intercellular Communication	Mediastinal adenopathy with mid-myocardial scar and/or focal myocardial inflammation was observed in 14 patients; lymph nodes revealed noncaseating granulomas in all.	21700089
SLC5A6 gene, Myocarditis	Altered Intercellular Communication	Decrease in SMVT correlated with resolution of myocardial inflammation on serial (18)FDG PET-CTs.	21700089
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Eosinophilic inflammation in chronic obstructive pulmonary disease (COPD) is predictive for responses to inhaled steroids.	21700610
Airway structure, ARCN1 gene	Altered Intercellular Communication	This suggests that breath analysis may be used for assessment and monitoring of airway inflammation in COPD.	21700610
vascular inflammations	Altered Intercellular Communication	In multivariate regression models adjusting for confounding variables, age remained independently associated with a composite Z score for systemic but not vascular inflammation (b=0.250, P<0.001, and b=0.276, P<0.001, for whites and African Americans, respectively).	21700927
Inflammation, Septic Shock	Altered Intercellular Communication	Glucocorticoids serve as important therapeutic agents in diseases of inflammation, but clinical use, especially in advanced septic shock, remains controversial because of the unpredictable response.	21701417
Upper Respiratory Infections	Altered Intercellular Communication	All patients had a mild clinical course and their respiratory capacity was stable between the second and third measurement, suggesting that the duration of respiratory inflammation was two months.	21702977
Respiratory Distress Syndrome, Adult, Inflammation	Altered Intercellular Communication	However, it remains unknown how alveolar IL-8 is related to pulmonary and systemic inflammation in patients predisposed for ARDS.	21703617
Inflammation, Pulmonary Complication, Traumatic injury	Altered Intercellular Communication	The enhanced alveolar and systemic inflammation associated with alveolar IL-8 release should be considered to identify high-risk patients for pulmonary complications after multiple trauma to adjust surgical and other treatment strategies to the individual risk profile.	21703617
Inflammation, Inflammatory disorder	Altered Intercellular Communication	LPAs are known to be key mediators in inflammation, and several lines of evidence suggest a role for LPAs in inflammatory periodontal diseases.	21703797
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Histopathologic examination of the resected appendix showed not only acute mucosal inflammation but also chronic inflammatory changes.	21703964
Inflammation, Heart failure, Anemia	Altered Intercellular Communication	Iron deficiency in community-dwelling US adults with self-reported heart failure in the National Health and Nutrition Examination Survey III: prevalence and associations with anemia and inflammation.	21705484
Inflammation, Carcinogenesis	Altered Intercellular Communication	Inflammation plays an important role in lung carcinogenesis.	21706174
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Recurrent 38 degrees C fever and inflammation were cured by clindamycin of 1.2 g/day.	21706849
Bronchitis	Altered Intercellular Communication	Bariatric surgery significantly reduces the intake of inhaled corticosteroids and the levels of exhaled nitric oxide, thus bronchial inflammation, in asthmatics.	21707447
Glaucoma, Primary Open Angle, Inflammation	Altered Intercellular Communication	Morphological and biochemical analyses of the TM of POAG patients revealed loss of cells, increased accumulation of extracellular matrix (ECM), changes in the cytoskeleton, cellular senescence and the process of subclinical inflammation.	21707516
Pain Distress Question, Conjunctivitis	Altered Intercellular Communication	Pain and conjunctival inflammation resolved in 11 patients (91.67%) and improved from severe to mild in the remaining patient.	21708086
Pain Distress Question, Inflammatory abnormality of the eye, Bulla	Altered Intercellular Communication	ASP combined with AMT is safe and effective, alleviates pain and discomfort, reduces ocular inflammation, and promotes epithelial healing and resolution of bullae in patients with BK with poor visual potential.	21708086
Inflammation	Altered Intercellular Communication	Measurements of joint thickening and joint inflammation were performed with Grey-scale and semi-quantitative Power-Doppler US (PDUS).	21708444
Pneumonitis	Altered Intercellular Communication	In Rag2(-/-)gc(-/-) immunodeficient mice reconstituted with human peripheral mononuclear cells (huPBMCs), PAM reduces disease severity and mortality caused by human seasonal H1N1 and avian H5N1 influenza virus, and controls the lung inflammation and viral replication.	21708931
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) are persistent environmental contaminants that affect metabolic regulation, inflammation, and other factors implicated in the pathogenesis of osteoarthritis (OA).	21709135
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Both inflammation and oxidative injury are features of Alzheimer's disease (AD), but the contribution of these intertwined phenomena to the loss of working memory in this disease is unclear.	21709376
Gingiva, Inflammatory disease of mucous membrane	Altered Intercellular Communication	At the beginning, bad dental and periodontal conditions with gingival signs and recurrent mucosal inflammation were found in all patients.	21709654
Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis	Altered Intercellular Communication	Inflammatory bowel diseases (IBD) include ulcerative colitis (UC) and Crohn's disease (CD), which are chronic inflammatory conditions affecting the gastrointestinal tract.	21710330
Inflammation, Head and neck structure, Malignant Neoplasms	Altered Intercellular Communication	Six cases were combined with local inflammation on head and neck and 2 cases were combined with malignant tumor.	21710715
Inflammation, Chronic purulent otitis media, Pain Distress Question	Altered Intercellular Communication	Chronic suppurative otitis media (CSOM) is frequently associated with symptoms of inflammation like discharge from the ear or pain.	21711571
Pruritus, Eczema	Altered Intercellular Communication	Nummular eczema is a chronic inflammatory condition characterized by pruritus and histologically characterized by spongiosis.	21712693
Inflammation, Primary malignant neoplasm, Unintentional weight loss	Altered Intercellular Communication	Utility of routine hematological and inflammation parameters for the diagnosis of cancer in involuntary weight loss.	21712730
Cessation of life, Inflammation, Primary malignant neoplasm, Anemia	Altered Intercellular Communication	Inflammation and anemia are associated with cancer, and recent studies showed that red blood cell distribution width (RDW) is a predictor of mortality, including cancer-related death.	21712730
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	In patients with IWL, the hematological and inflammation parameters were statistically different in patients with cancer and in those without cancer.	21712730
Communicable Diseases, Thrombosis, Arteritis, Atherosclerosis	Altered Intercellular Communication	The chronic infection status suffered by HIV-infected individuals promotes chronic arterial inflammation and injury, which leads to dysfunction of the endothelium, atherosclerosis and thrombosis.	21713302
Inflammation, Thrombosis	Altered Intercellular Communication	Circulating microparticles (MPs) are involved in thrombosis, inflammation, and angiogenesis.	21713319
Inflammation, Degenerative disorder	Altered Intercellular Communication	Recent studies have shown that renin-angiotensin system overactivation is involved in the aging process in several tissues as well as in longevity and aging-related degenerative diseases by increasing oxidative damage and inflammation.	21713375
Inflammation, Dyslipidemias	Altered Intercellular Communication	Mixed dyslipidemia, oxidative stress and inflammation are related to a high risk for cardiovascular events.	21714585
Refractory anemias, Inflammation	Altered Intercellular Communication	YKL-40 concentrations are elevated in the serum of patients with RA compared to healthy subjects, and YKL-40 has been suggested to be an auto-antigen and may play a role in development of RA and in inflammation.	21714862
Acute Kidney Injury, CTCAE, Inflammation, Malnutrition, Kidney Failure, Acute	Altered Intercellular Communication	Animal and human studies suggest that inflammation and malnutrition are common in acute kidney injury (AKI) patients.	21714897
Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	However, only a few studies reported CRP, a marker of inflammation, albumin, prealbumin and cholesterol, markers of nutritional status were associated with the prognosis of AKI patients.	21714897
Inflammation, Malnutrition, Kidney Failure, Acute	Altered Intercellular Communication	Inflammation and malnutrition were common in patients with AKI.	21714897
Degenerative polyarthritis, Inflammation, Tumor necrosis, Knee pain	Altered Intercellular Communication	One of the sources of knee pain in osteoarthritis (OA) is believed to be related to local chronic inflammation of the knee joints, which involves the production of inflammatory cytokines such as tumor necrosis factor alpha (TNFa), interleukin (IL)-6, and nerve growth factor (NGF) in the synovial membrane, and these cytokines are believed to promote pathological OA.	21714933
Folliculitis, Blepharitis, Rosacea, Ear Inflammation, Alopecia, CTCAE, Disease	Altered Intercellular Communication	Their role in human diseases is under investigation, and a growing number of studies indicated that they contribute to chronic inflammatory conditions of the skin, such as rosacea, blepharitis, otitis externa, alopecia and folliculitis.	21715284
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Association between depression and inflammation--differences by race and sex: the META-Health study.	21715300
Inflammation, Depression, CTCAE	Altered Intercellular Communication	To test whether the association between depression and inflammation differs by race and sex.	21715300
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Although depressive symptoms are associated with inflammation, the association varies by race and sex.	21715300
Inflammation	Altered Intercellular Communication	Chronic inflammation of the lamina propria was present in 9 cases, and focal neutrophil infiltration was identified in 3 cases.	21716082
Inflammation, Vasculitis of large artery	Altered Intercellular Communication	Antigen-antibody (IgA) complexes activate the alternative complement pathway, resulting in inflammation and small vessels vasculitis.	21717040
Influenza due to Influenza A virus subtype H1N1, Inflammation	Altered Intercellular Communication	In contrast to several reports so far, CT findings of H1N1 virus infection in patients with mild illness are variable, including suggestive findings of inflammation involving large and/or small airways.	21717297
Pain Distress Question, Inflammation	Altered Intercellular Communication	To assess the efficacy of sclerosant Polidocanol in foam form compared to liquid form and to determine safety profile by monitoring the complications (Pain, inflammation and pigmentation).	21717876
Pain Distress Question, Hyperpigmentation, Inflammation	Altered Intercellular Communication	However Pain, inflammation, and hyperpigmentation appeared more often with foam Polidocanol therapy.	21717876
Granulomatous inflammation, Hyperplasia	Altered Intercellular Communication	Histopathological examination of the skin biopsy revealed epidermal hyperplasia and granulomatous inflammation in the dermis, with budding yeast.	21719337
vascular inflammations, Pathologic Processes	Altered Intercellular Communication	BD is a rare, chronic multi-systemic vasculitis and interaction of activated platelets with leucocytes has been linked to pathological disorders associated with vascular inflammation.	21719422
Waldenstrom Macroglobulinemia, Fibrosis Assessment, Phlebitis	Altered Intercellular Communication	The lesion of ISD is characterised by lymphoplasmacytic inflammation, fibrosis, phlebitis and increased numbers of IgG4-positive plasma cells.	21719489
Inflammation	Altered Intercellular Communication	In neither apparently healthy nor the entire population was inflammation associated with airflow limitation in central airways.	21719491
Inflammation, Smoking	Altered Intercellular Communication	Smoking is related to an impaired D(L,CO) in association with an increase in systemic inflammation.	21719491
Inflammation	Altered Intercellular Communication	The object was surrounded by a low-density area, suggesting severe inflammation.	21720094
Inflammation	Altered Intercellular Communication	Severe inflammation of the right renal vein was observed.	21720094
Inflammation	Altered Intercellular Communication	At surgery, the gallbladder wall was observed to be extremely thick because of severe inflammation, and cholecystectomy was performed.	21720095
Inflammation, Hypoxia	Altered Intercellular Communication	Immunologically restricted patients exhibit a pronounced inflammation and inadequate response to hypoxia in fracture hematomas.	21720875
Inflammation, HIV Infections	Altered Intercellular Communication	Increased plasma levels of extracellular mitochondrial DNA during HIV infection: a new role for mitochondrial damage-associated molecular patterns during inflammation.	21722755
Inflammation	Altered Intercellular Communication	The relationship of serum PON-1 activity with SAA during low-grade chronic inflammation is unclear.	21722818
Inflammation, Electrocardiogram: left ventricle hypertrophy (finding), SLC22A5 gene	Altered Intercellular Communication	CAE is common in SCD and is associated with left ventricular hypertrophy and inflammation.	21722914
Celiac Disease, Inflammation, Malignant neoplasm of gastrointestinal tract	Altered Intercellular Communication	Low risk of gastrointestinal cancer among patients with celiac disease, inflammation, or latent celiac disease.	21723236
Celiac Disease, Inflammation, Malignant neoplasm of gastrointestinal tract	Altered Intercellular Communication	Of patients with celiac disease, 372 developed incident GI cancers; 347 patients with inflammation and 38 with latent celiac disease developed GI cancers.	21723236
Celiac Disease, Inflammation, Malignant neoplasm of gastrointestinal tract	Altered Intercellular Communication	In the first year after diagnosis and initial biopsy, celiac disease was associated with 5.95-fold increase in risk of incident GI cancer (95% confidence interval [CI], 4.64-7.64); the hazard ratio [HR] for inflammation was 9.13 (95% CI, 7.19-11.6) and for latent celiac disease was 8.10 (95% CI, 4.69-14.0).	21723236
Celiac Disease, Inflammation, Malignant neoplasm of gastrointestinal tract	Altered Intercellular Communication	After the first year, patients were at no significant increase in risk for GI cancers; the HR for celiac disease was 1.07 (95% CI, 0.93-1.23), for inflammation it was 1.16 (95% CI, 0.98-1.37), and for latent celiac disease it was 0.96 (95% CI, 0.56-1.66).	21723236
Celiac Disease, Inflammation, Malignant neoplasm of gastrointestinal tract	Altered Intercellular Communication	Although celiac disease, inflammation, and latent disease all increase risk for GI cancers in the first year after diagnosis, there is no increase in risk thereafter.	21723236
Communicable Diseases, Inflammation, Granulation finding, Necrosis	Altered Intercellular Communication	The wound severity scores, which vary with the severity of infection and inflammation, necrotic and granulation tissues, and wound depth and area, were assessed weekly for 9 weeks.	21723750
Inflammation, Necrosis	Altered Intercellular Communication	Subgroup analyses comparing the WF10 and placebo groups showed statistically significant decreases of infection and inflammation (0.0 +- 0.0 versus 0.8 +- 0.9, respectively, p < .01), necrotic tissue (0.0 +- 0.0 versus 0.8 +- 1.1, respectively, p < .01), and an increase of the amount of granulation tissue (0.1 +- 0.3 versus 0.8 +- 1.2, respectively, p < .05).	21723750
Communicable Diseases, Inflammation, Necrosis	Altered Intercellular Communication	We concluded that the addition of WF10 to standard wound care statistically significantly reduced the wound severity score, infection and inflammation, and necrotic tissue and enhanced the formation of granulation tissue.	21723750
Inflammation	Altered Intercellular Communication	CyPA may represent a novel and specific marker for cardiac inflammation.	21724278
Primary malignant neoplasm	Altered Intercellular Communication	A comparison of inflammation-based prognostic scores in patients with cancer.	21724383
Primary malignant neoplasm	Altered Intercellular Communication	Components of the systemic inflammatory response, combined to form inflammation-based prognostic scores (modified Glasgow Prognostic Score (mGPS), Neutrophil Lymphocyte Ratio (NLR), Platelet Lymphocyte Ratio (PLR), Prognostic Index (PI), Prognostic Nutritional Index (PNI)) have been associated with cancer specific survival.	21724383
Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	The results of the present study show that systemic inflammation-based scores, in particular the mGPS and PI, have prognostic value in cancer independent of tumour site.	21724383
Abnormal gastrointestinal motility, Inflammation, Stasis	Altered Intercellular Communication	Clinical course is benign and etiology unclear, but it has been associated to chronic inflammation due to fecal stasis and abnormal colonic motility.	21724496
Inflammation, Carcinogenesis, Neoplasms	Altered Intercellular Communication	Vitamin D and calcium affect several pathways involved in inflammation, tumor growth, and immune surveillance relevant to carcinogenesis.	21724580
Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Atrial fibrillation (AF) is associated not only with inflammation but also with structural remodelling and altered endothelial activation which may contribute to clot formation, embolization and mortality.	21725858
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Hemodialysis (HD)-induced inflammation has a pathogenetic role in patients with end-stage renal disease (ESRD).	21725917
Inflammation	Altered Intercellular Communication	Role of the hemodialysis vascular access type in inflammation status and monocyte activation.	21725929
Inflammation, Congestion	Altered Intercellular Communication	Monotherapy of imiquimod is less effective than the two other regimens in decreasing parasite load, inflammation and congestion at the inoculated site.	21726098
Inflammation, Atherosclerosis	Altered Intercellular Communication	Peroxisome proliferator-activated receptor-g (PPARg) is involved in regulation of macrophage inflammation and in atherosclerosis.	21726861
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Inflammation is a risk factor for coronary heart disease (CHD).	21726863
Inflammation, Data types - Address	Altered Intercellular Communication	The involvement of ADAM8 and -15 together with inflammation consisting of B-cells may indicate active remodelling of the aortic wall leading to AD.	21728902
Inflammation, Fever, CTCAE	Altered Intercellular Communication	It also significantly reduced inflammation frequency and shortened high fever duration.	21729572
Airway structure, Asthma, Allergy - Charge Type Reason	Altered Intercellular Communication	Effect of urbanisation on asthma, allergy and airways inflammation in a developing country setting.	21730351
Asthma	Altered Intercellular Communication	Peri-urban adolescents had more asthma, atopy and airways inflammation and were exposed to more indoor pollution.	21730351
Acute hepatitis	Altered Intercellular Communication	Interleukin-8 (IL-8, CXCL8) is a potent chemoattractant for neutrophils and contributes to acute liver inflammation.	21731723
Hepatic inflammation, Lymphoproliferative Disorder of the Skin	Altered Intercellular Communication	IL-8 is strongly activated in CLD, thus likely contributing to hepatic inflammation.	21731723
Chorioretinitis, Inflammation, Toxoplasmosis, Panuveitis	Altered Intercellular Communication	In toxoplasmosis patients, positive RT-PCR results were statistically correlated with the chorioretinitis area (more than three disc areas; p = 0.002), with the age older than 50 (p = 0.0034) and with a clinical anterior inflammation (Tyndall >=1/2+) and panuveitis; (p = 0.0001).	21732111
Intraocular inflammation	Altered Intercellular Communication	For the diagnosis of viral or toxoplasmosis-associated intraocular inflammation, the usefulness of laboratory diagnosis tools (RT-PCR and GWC) depends on parameters other than the sensitivity of the tests.	21732111
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	The vulnerable atherosclerotic lesion exhibits the proliferation of neovessels and inflammation.	21732164
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	The disease can progress from an asymptomatic inflammation to a cirrhosis.	21732301
Inflammatory abnormality of the eye, Visual blurring, Influenza	Altered Intercellular Communication	The authors recommend alertness for visual blurring and ocular inflammation after influenza A infection.	21732577
Schizophrenia, Parkinsonian Disorders	Altered Intercellular Communication	D-serine (DSR) allosterically modulates in-vivo NMDAR-mediated neurotransmission and has been shown to improve negative and antipsychotic drug-induced parkinsonian symptoms in schizophrenia patients.	21733283
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Inflammation is a hallmark of the metabolic syndrome, which also contributes to a pro-atherogenic state.	21733322
vascular inflammations, atherosclerotic	Altered Intercellular Communication	Carotid [(18)F]-FDG uptake, an index of vascular inflammation within the atherosclerotic plaques, was measured as standardized uptake value (SUV).	21733518
vascular inflammations, International Medical Terminology, Atherosclerosis	Altered Intercellular Communication	The present study reveals that serum level of PEDF is independently associated with vascular inflammation and IMT, thus suggesting that PEDF level is a novel biomarker that could reflect atherosclerosis in humans.	21733518
Inflammation, Fever, CTCAE, Arthritis, Infectious	Altered Intercellular Communication	Fever and signs of inflammation were more frequent and synovial fluid cell counts were higher in patients with improbable septic arthritis.	21733734
Diabetic Nephropathy, Inflammation	Altered Intercellular Communication	Endogenous erythropoietin and the association with inflammation and mortality in diabetic chronic kidney disease.	21734083
Inflammation, Anemia, Chronic Kidney Diseases, diabetic	Altered Intercellular Communication	Anemia and inflammation are prevalent in diabetic patients with chronic kidney disease (CKD).	21734083
Inflammation, Chronic Kidney Diseases, diabetic	Altered Intercellular Communication	In diabetic patients with CKD, elevated endogenous EPO levels were predictive for mortality and were related mainly to markers of inflammation, independent of kidney function, and despite low hemoglobin levels.	21734083
Inflammation, Inflammatory disorder	Altered Intercellular Communication	EBC may be useful in measuring inflammation in several inflammatory lung diseases.	21734340
Inflammation, Primary malignant neoplasm, Neoplasm Metastasis	Altered Intercellular Communication	Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer".	21734470
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	In this regard, a series of recent studies have elegantly shown that the production of hydrogen peroxide, by both cancer cells and cancer-associated fibroblasts, may provide the necessary "fertilizer," by driving accelerated aging, DNA damage, inflammation and cancer metabolism, in the tumor microenvironment.	21734470
Alzheimers Disease	Altered Intercellular Communication	The superior colliculus and retina obtained from late-stage Alzheimer's disease revealed upregulated amyloidogenic and inflammatory signaling along the anteroposterior axis of the retinal-primary visual cortex pathway.	21734608
allergic inflammation	Altered Intercellular Communication	We believe that Aspergillus clusters may have been present in this patient for several years, and the pathological findings might be manifested as an asymptomatic localized allergic inflammation.	21735744
Vitreous inflammatory cells	Altered Intercellular Communication	Sudden severe anterior chamber and vitreous inflammation occurred beginning on the day following surgery, but it disappeared spontaneously without complications.	21735756
Inflammation	Altered Intercellular Communication	Macrophage accumulation enhances chronic inflammation in adipose tissue, but macrophage phenotypic change in human epicardial adipose tissue and its role in atherogenesis are unknown.	21737014
Gustatory rhinitis, Rhinitis	Altered Intercellular Communication	Other causes of rhinitis: mixed rhinitis, rhinitis medicamentosa, hormonal rhinitis, rhinitis of the elderly, and gustatory rhinitis.	21737037
Rhinitis, Acromegaly, Gustatory rhinitis, Drug Eruptions, Rhinitis, Atrophic, Common Cold, IL13 gene, Occupational	Altered Intercellular Communication	It is important to consider a comprehensive differential of possible rhinitis types when considering the diagnosis of chronic rhinitis, including at least 9 subtypes of nonallergic rhinitis: drug-induced rhinitis, gustatory rhinitis, hormonal-induced rhinitis, infectious rhinitis, nonallergic rhinitis with eosinophilia syndrome, occupational rhinitis, senile rhinitis, atrophic rhinitis, and nonallergic rhinopathy.	21737037
Inflammation, Thrombosis	Altered Intercellular Communication	Patients with severe protein C deficiency had lower arterial blood pressure (P = .0006), greater serum creatinine concentration (P < .0001), elevated markers of thrombosis and inflammation, and impairment of fibrinolysis (P < .0001).	21737232
Inflammation, Obesity	Altered Intercellular Communication	Impaired lung function has been linked to obesity and systemic inflammation.	21737489
Communicable Diseases, Inflammation, Traumatic injury	Altered Intercellular Communication	Progressive inflammation of the arachnoid mater due to trauma, infection, or hydrocortisone was reported as early as the 1970s.	21738091
Inflammation, Neoplasms	Altered Intercellular Communication	The low expression of membranous b-catenin was associated with a high degree of tumor infiltration (p = 0.02), high amount of inflammation (p = 0.01), and high degree of poor tumor differentiation (p < 0.001).	21739269
Sebaceous Adenocarcinoma, Inflammation, Neoplasms	Altered Intercellular Communication	These changes were associated with poor tumor differentiation and an increase in the tumor infiltration and inflammation, pointing at a potential role of a low E-cadherin and low b-catenin expression for poor prognosis of sebaceous eyelid adenocarcinomas.	21739269
Inflammation	Altered Intercellular Communication	Low levels of IGF-1 in RA synovial fluid were associated with systemic inflammation and inversely related to the levels of resistin.	21739426
Rupture, Angina, Unstable	Altered Intercellular Communication	Inflammation within vulnerable coronary plaques may cause unstable angina by promoting rupture and erosion.	21740772
Inflammation, Fever, CTCAE, Lymphadenopathy	Altered Intercellular Communication	[Diagnostic value of lymphadenopathy associated with fever and inflammation of unknown origin: a study of 69 patients].	21741135
Inflammation, Fever, CTCAE	Altered Intercellular Communication	The diagnosis of fever or inflammation of unknown origin (FUO/IUO) is guided by the search of clinical clues.	21741135
Inflammation	Altered Intercellular Communication	In general, genes associated with inflammation (such as RANKL and CD68) were overexpressed in symptomatic compared with asymptomatic plaques.	21741279
Supranuclear paralysis, Inflammation	Altered Intercellular Communication	Although little is known about the etiology of progressive supranuclear palsy (PSP), genetic and epigenetic factors, oxidative injury and inflammation are thought to contribute to its development and/or progression.	21741294
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Abdominal aortic aneurysms (AAA) are associated with inflammation, apoptosis, and matrix degradation.	21741794
Pterygium Of Conjunctiva And Cornea	Altered Intercellular Communication	Postoperative conjunctival inflammation after pterygium surgery with amniotic membrane transplantation versus conjunctival autograft.	21742306
Pterygium Of Conjunctiva And Cornea, Conjunctivitis	Altered Intercellular Communication	Main outcome measures included presence of host conjunctival inflammation around the surgical site at 1 month after surgery and also recurrence of pterygium.	21742306
Conjunctivitis	Altered Intercellular Communication	At 1 month after surgery, different grades of host conjunctival inflammation were present in 16 eyes (84.2%) in the AMT group and in 3 eyes (15%) in the conjunctival autograft group (P = .02).	21742306
Pterygium Of Conjunctiva And Cornea, Conjunctivitis	Altered Intercellular Communication	After pterygium surgery, conjunctival inflammation was significantly more common with AMT than with conjunctival autograft.	21742306
Inflammation, Giant Cell Arteritis, Atheroma	Altered Intercellular Communication	[Peripheral arterial involvement in giant cell arteritis: how to differentiate between atheroma and inflammation?].	21742449
Refractory anemias, Rheumatoid Arthritis, destruction joint, Inflammation	Altered Intercellular Communication	In rheumatoid arthritis (RA), a complex cytokine network drives chronic inflammation and joint destruction.	21742639
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	To analyse the expression of SIRT1 in synovial tissues and cells of patients with rheumatoid arthritis (RA) and to study the function of SIRT1 in inflammation and apoptosis in RA.	21742641
Inflammation	Altered Intercellular Communication	The TNFa-induced overexpression of SIRT1 in RA synovial cells contributes to chronic inflammation by promoting proinflammatory cytokine production and inhibiting apoptosis.	21742641
Inflammation	Altered Intercellular Communication	The reduction in CFH amount or its complement-modulating activity may lead to inadequate control of complement-driven inflammation at the outer retina.	21743006
Inflammation	Altered Intercellular Communication	These results suggest a new perspective of the interaction between oxidative stress and inflammation, and provide a potential novel treatment strategy for age-related macular degeneration.	21743006
Behavioral Symptoms, Data types - Address	Altered Intercellular Communication	An imbalance of different neurotransmitters--glutamate, acetylcholine, dopamine, and serotonin--has been proposed as the neurobiological basis of behavioral symptoms in AD.	21743130
Granulomatous inflammation, Crohn Disease	Altered Intercellular Communication	Bilateral dacryocystorhinostomies were performed through an external approach and revealed multiple nodular masses in both lacrimal sacs, which on biopsy, contained granulomatous inflammation consistent with extraintestinal Crohn disease.	21743368
Nasolacrimal Duct Obstruction, Crohn Disease, Granulomatous inflammation	Altered Intercellular Communication	A literature search from 1966 to the present using the PubMed database revealed three previous publications describing nasolacrimal duct obstruction associated with Crohn disease, but these cases did not show pathologic evidence of granulomatous inflammation.	21743368
Crohn Disease, Granulomatous inflammation	Altered Intercellular Communication	To our knowledge, this is the first reported case of extraintestinal Crohn disease with granulomatous inflammation affecting the lacrimal-outflow system.	21743368
Abnormality of levator veli palatini muscle, Fibrosis Assessment, Inflammation, Atrophic	Altered Intercellular Communication	Histopathologic specimens revealed abnormal levator muscle fibers with various degrees of atrophy, fibrosis, and regeneration without inflammation.	21743372
Eosinophilic inflammation	Altered Intercellular Communication	Nasal lavage CCL24 levels correlate with eosinophils trafficking and symptoms in chronic sino-nasal eosinophilic inflammation.	21743872
Airway structure, Sleep Apnea, Obstructive	Altered Intercellular Communication	Obstructive sleep apnea syndrome (OSAS) has been shown to be associated to upper and lower airways inflammation.	21743883
Airway structure, Sleep Apnea, Obstructive	Altered Intercellular Communication	In 13 non-smoking subjects affected by untreated OSAS and in 11 non-smoking normal volunteers, airway inflammation was detected by analyses of the induced sputum.	21743883
Sleep Apnea, Obstructive, Nasal inflammation	Altered Intercellular Communication	In addition, in 12 subjects of the OSAS group, nasal inflammation was detected by the analysis of induced nasal secretions at baseline, and after 1, 10 and 60 days of CPAP treatment.	21743883
Inflammation, Biliary Tract Cancer	Altered Intercellular Communication	Medical history and the risk of biliary tract cancers in Shanghai, China: implications for a role of inflammation.	21744094
Inflammation, Biliary Tract Cancer	Altered Intercellular Communication	Several lines of evidence suggest that inflammation may play a role in the etiology of biliary tract cancers.	21744094
Biliary Tract Cancer	Altered Intercellular Communication	We used logistic regression to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for biliary tract cancers in relation to six inflammation-related conditions.	21744094
Inflammation, Biliary Tract Cancer	Altered Intercellular Communication	Although the mechanisms are unclear, our results further support the role for inflammation in the etiology of biliary tract cancers.	21744094
Inflammation, Calcification of coronary artery, Autoimmune Diseases, Myocardial Reperfusion, Lupus Erythematosus	Altered Intercellular Communication	Influence of chronic inflammation and autoimmunity on coronary calcifications and myocardial perfusion defects in systemic lupus erythematosus patients.	21744266
Inflammation, Calcification of coronary artery, Coronary Artery Disease, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Conventional risk factors for coronary artery disease as well as markers of an ongoing inflammation did not show any association with perfusion defects and/or coronary artery calcifications in SLE patients.	21744266
Inflammation, Restenosis	Altered Intercellular Communication	The peptide from C-terminal domain of MCP-1 (Ingramon) has been shown to inhibit monocyte migration and possess anti-inflammatory activity in animal models of inflammation and post-angioplasty restenosis.	21744268
Hepatic inflammation	Altered Intercellular Communication	Variability at the IL28B locus is associated with HBV viral load and hepatic inflammation.	21745278
Hepatitis	Altered Intercellular Communication	Genetic variation of IL28B may prevent HBV progression by reducing viral load and liver inflammation, providing a valuable gene therapy tool.	21745278
Hepatitis	Altered Intercellular Communication	The correlation between liver histology and serum markers of liver inflammation was analysed.	21745311
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	On the basis of multivariate analysis, the AST and apolipoprotein A1 levels and stage of fibrosis were highly predictive of significant inflammation.	21745311
Inflammation, "Alzheimers Disease", Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	These include chronic low-grade inflammation (inflammageing), a major risk factor for ageing and age-related diseases, such as Alzheimer's disease and type II diabetes.	21745717
Inflammation, "Alzheimers Disease", Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	These include chronic low-grade inflammation (inflammageing), a major risk factor for ageing and age-related diseases, such as Alzheimer's disease and type II diabetes.	21745717
Inflammation, Fibrosis Assessment, Waldenstrom Macroglobulinemia	Altered Intercellular Communication	Multifocal fibrosclerosis(MFS) is a rare disorder of unknown etiology, characterized by chronic inflammation with dense fibrosis and lymphoplasmacytic infiltration into the connective tissue of various organs.	21747150
Inflammation	Altered Intercellular Communication	The RA synovial compartment contains several ligands for CCR1, CCR2, and CCR5 as well as other chemokines and receptors involved in monocyte recruitment to the site of inflammation.	21747955
Pain Distress Question, Irritation, Inflammation	Altered Intercellular Communication	Yet up to one-third of patients complain of post-surgical pain due to irritation and inflammation caused by the mesh and the fixation materials.	21748483
Inflammation, Hemorrhage, Pain, Postoperative	Altered Intercellular Communication	Because excessive bleeding can increase postoperative pain and inflammation, use of PRP also reportedly decreases the need for narcotics and increases speed of recovery after TKA.	21748512
palladium, Inflammation	Altered Intercellular Communication	PD and PSP subjects also had increases in microglia number and activation in the SN(pc) suggesting a link between inflammation and clinical disease.	21748523
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Primary outcome revealed no significant difference between treatment groups in all histologic parameters (steatosis, P = 0.137; hepatocellular inflammation, P = 0.320; fibrosis, P = 0.229).	21748770
Inflammatory Hepatocellular Adenoma, Fatty degeneration, Fibrosis Assessment, Balloon Dilatation	Altered Intercellular Communication	Overall improvement in steatosis, hepatocellular inflammation, ballooning degeneration, and fibrosis was observed (P <= 0.001).	21748770
Structure of cavernous sinus, Inflammation, Sinus Thrombosis, Intracranial, Venous hypertension, Traumatic injury, Dural Arteriovenous Fistula	Altered Intercellular Communication	Although hormonal influences, inflammation, trauma, sinus thrombosis, venous hypertension, and congenital origin have been proposed as sources of dural arteriovenous fistulas (DAVFs) in cavernous and sigmoid sinuses, the etiology of these lesions remains controversial.	21748936
Inflammation, Viral meningitis	Altered Intercellular Communication	The viral meningitis most likely caused the inflammation, that may be responsible for the occurrence of the cavernous sinus DAVF.	21748936
Inflammation	Altered Intercellular Communication	Prompt treatment for inflammation may help to prevent the development of DAVFs.	21748936
Structure of cavernous sinus, Inflammation, Sinus Thrombosis, Intracranial, Venous hypertension, Traumatic injury, Dural Arteriovenous Fistula	Altered Intercellular Communication	Although hormonal influences, inflammation, trauma, sinus thrombosis, venous hypertension, and congenital origin have been proposed as sources of dural arteriovenous fistulas (DAVFs) in cavernous and sigmoid sinuses, the etiology of these lesions remains controversial.	21748936
Inflammation, Chronic disease	Altered Intercellular Communication	Inflammation is a common pathophysiological pathway for a number of chronic diseases, and is strongly influenced by sociodemographic factors and lifestyle.	21749016
Inflammation, Periodontitis, Metabolic Syndrome X, Atherosclerosis, ETV3 wt Allele	Altered Intercellular Communication	The systemic inflammation in both metabolic syndrome (MetS) and periodontitis is a common denominator of the association of these conditions with higher risk of atherosclerosis.	21749167
Trachoma , Tebi	Altered Intercellular Communication	A trachoma case was defined by the presence of Trachomatous inflammation-Follicular (TF) and/or Trachomatous inflammation-Intense (TI) in either eye.	21749703
Gastroesophageal reflux disease, Communicable Diseases, Gastro-esophageal reflux disease with esophagitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	To compare the characteristics of the traditional Chinese medicine (TCM) syndromes of gallbladder heat attacking the stomach and stagnant heat of the liver and stomach in patients with reflux esophagitis (RE), in terms of clinical symptoms, combination of gallbladder conditions, esophageal mucosal inflammation, gastric bile reflux under endoscopy and helicobacter pylori (HP) infection.	21749823
Gastroesophageal reflux disease, Communicable Diseases, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The general data, characteristics of clinical symptoms, combination of gallbladder conditions, esophageal mucosal inflammation, gastric bile reflux under endoscopy and HP infection of the two patterns were compared.	21749823
Gastroesophageal reflux disease, Communicable Diseases, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The extent of the esophageal mucosal inflammation under endoscopy as well as the gastric bile reflux and the incidence of HP infection was also more severe (P<0.01).	21749823
Inflammation, Diplopia, Fibrosis Assessment, Scleroderma , Enophthalmos	Altered Intercellular Communication	Inflammation and progressive collagen fibrosis involving subcutaneous tissue, fat, and muscle secondary to linear scleroderma may result in enophthalmos and diplopia.	21750423
Degenerative polyarthritis, Inflammation, Degenerative disorder of cartilage	Altered Intercellular Communication	Osteoarthritis (OA) is considered a complex illness, characterized by cartilage degeneration, secondary synovial membrane inflammation, and subchondral bone sclerosis.	21750942
Granuloma, Inflammation	Altered Intercellular Communication	Dalen-Fuchs nodules (DFN), granulomas, and non-granulomatous foci of inflammation were micro-dissected from 15 cases.	21751146
Conjunctivitis, Keratoconjunctivitis Sicca	Altered Intercellular Communication	After the treatment, above all else the clinical signs of conjunctival inflammation disappeared, but remained KCS symptoms, which were disappearing only slowly.	21751740
Pain Distress Question, Inflammatory abnormality of the eye	Altered Intercellular Communication	Once daily dosing of bromfenac ophthalmic solution 0.09% for postoperative ocular inflammation and pain.	21751945
Inflammatory abnormality of the eye	Altered Intercellular Communication	The primary efficacy endpoint was cleared summed ocular inflammation score (SOIS) by Day 15.	21751945
Inflammatory abnormality of the eye	Altered Intercellular Communication	The bromfenac 0.09% group was significantly higher compared to the placebo group in the primary endpoint of the proportion of subjects who had cleared ocular inflammation by Day 15 (P < 0.0001).	21751945
Cataract, Eye pain, Inflammatory abnormality of the eye	Altered Intercellular Communication	Bromfenac ophthalmic solution 0.09% dosed once daily is clinically safe and effective for the treatment of ocular inflammation and the reduction of ocular pain associated with cataract surgery.	21751945
Tissue damage, Inflammation	Altered Intercellular Communication	Cytokine expression is upregulated in chronic CD patients; therefore, the degree of inflammation and tissue damage in CD is dependent on the expression of specific cytokines within the tissue.	21752952
Delirium, "Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	In Alzheimer disease (AD), systemic inflammation is known to give rise to a delirium.	21753171
Delirium, Inflammation, Illness Behavior	Altered Intercellular Communication	However, systemic inflammation also gives rise to other centrally mediated symptoms in the absence of a delirium, a concept known as sickness behavior.	21753171
Inflammation, Tumor necrosis, Illness Behavior	Altered Intercellular Communication	Systemic inflammation is characterized by the systemic production of the proinflammatory cytokines tumor necrosis factor-a (TNFa) and interleukin-6 (IL-6) that mediate immune to brain communication and the development of sickness behavior.	21753171
Refractory anemias, Rheumatoid Arthritis, destruction joint, Inflammation	Altered Intercellular Communication	Matrix metalloproteinases (MMPs) are involved in joint destruction in rheumatoid arthritis (RA), and are strongly associated with levels of inflammation.	21753786
Inflammation, Weight decreased, Overweight	Altered Intercellular Communication	Weight loss combined with exercise may reduce inflammation and improve physical functioning in overweight, sedentary, older adults.	21753869
Pneumonitis	Altered Intercellular Communication	Significant variability in the severity and duration of ARDS-associated pulmonary inflammation could be linked to heterogeneity in the inflammatory capacity of neutrophils.	21755013
Inflammation	Altered Intercellular Communication	The excessive inflammation at the prosthesis-corneal junction and the unsuited height of the optical cylinder might have been the main reasons of STP.	21756746
Inflammation, Depressed mood	Altered Intercellular Communication	Depressed individuals not only suffer from chronic low grade inflammation, but also exhibit an inflammatory hyper-responsiveness to acute stress.	21756997
vascular inflammations	Altered Intercellular Communication	Effects of marine omega-3 fatty acids on serum systemic and vascular inflammation markers and oxidative stress in hemodialysis patients.	21757893
Inflammation, vascular inflammations, Cardiovascular Diseases	Altered Intercellular Communication	High concentrations of serum inflammation markers, especially vascular inflammation markers, are an important risk factor for cardiovascular diseases in hemodialysis patients.	21757893
HD Term Type, Inflammation, Cardiac dysfunction	Altered Intercellular Communication	Our study pointed out that BNP >1,200 pg/ml as a marker of cardiac dysfunction and CRP >= 10 mg/l as a marker of inflammation identify HD patients at increased risk of CV mortality.	21757955
Inflammation, Tooth Loss, Obesity	Altered Intercellular Communication	Total tooth loss and systemic correlates of inflammation: role of obesity.	21760638
Inflammation, Tooth Loss	Altered Intercellular Communication	In conclusion, subjects with total tooth loss, although devoid of periodontal inflammation, may exhibit increased levels of systemic inflammatory mediators.	21760638
Inflammation, Obesity	Altered Intercellular Communication	Possible implications are discussed with respect to obesity and its relationship to inflammation.	21760638
Inflammation, Musculoskeletal, Pain Distress Question	Altered Intercellular Communication	Despite these advances, in some patients inflammation is not diminished sufficiently to prevent irreversible musculoskeletal damage, thereby necessitating surgical intervention to reduce pain and improve function.	21761229
Inflammation, Prostate carcinoma, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	Testosterone and inflammation have been linked to the development of common age-associated diseases affecting the prostate gland including prostate cancer, prostatitis, and benign prostatic hypertrophy.	21761342
Prostate, prostatitis	Altered Intercellular Communication	These data demonstrate that tight junction architecture in the prostate is related to changes in serum testosterone levels, and identify an androgen-regulated mechanism that potentially contributes to the development of prostate inflammation and consequent pathology.	21761342
Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	Examinations for gingival inflammation (MGI), bleeding and plaque were performed after 12 weeks.	21762151
Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	Examinations for gingival inflammation (MGI), bleeding and plaque were performed after 6 and 12 weeks.	21762150
methyldopa, Inflammation	Altered Intercellular Communication	Inflammation, among many factors, has been suggested to play an important role in AMD pathogenesis.	21762495
methyldopa, Inflammation	Altered Intercellular Communication	The possible involvement of IL-22 and IL-17 in the inflammation that contributes to AMD may herald a new approach to treat AMD.	21762495
Capillaritis, Interstitial inflammation	Altered Intercellular Communication	Neutrophil predominant capillaritis and interstitial inflammation is an uncommon renal biopsy finding, with a broad differential diagnosis.	21762649
Capillaritis, Interstitial inflammation	Altered Intercellular Communication	Renal biopsy demonstrated prominent neutrophilic capillaritis with interstitial inflammation, and fibrinoid deposits in medullary capillaries and interstitium.	21762649
Inflammation, Metabolic Syndrome X, MS gene	Altered Intercellular Communication	We investigated an association between lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) activity, inflammation, and oxidative stress in women with metabolic syndrome (MS).	21762913
Inflammation	Altered Intercellular Communication	This association was also affected by menopause status, suggesting that Lp-PLA(2) may represent a novel marker for oxidation and inflammation in MS.	21762913
Pain Distress Question, Inflammatory abnormality of the eye	Altered Intercellular Communication	Safety and efficacy of bromfenac ophthalmic solution (Bromday) dosed once daily for postoperative ocular inflammation and pain.	21762992
Inflammatory abnormality of the eye	Altered Intercellular Communication	The proportion of subjects who had cleared ocular inflammation by day 15 was significantly higher in the bromfenac 0.09% group than in the placebo group (P < 0.0001).	21762992
Cataract, Pain Distress Question, Inflammatory abnormality of the eye	Altered Intercellular Communication	Bromfenac 0.09% dosed once daily was clinically safe and effective for reducing and treating ocular inflammation and pain associated with cataract surgery.	21762992
Inflammation, Frailty, Chronic disease	Altered Intercellular Communication	Frailty is associated with a pro-inflammatory state, which has been characterized by elevated levels of systemic inflammatory biomarkers, but has not been related to the number of co-existing chronic diseases associated with inflammation.	21763008
Inflammation, Central heterochromia, Keratitis, Conjunctival hyperemia, Corneal edema	Altered Intercellular Communication	Age, gender, and diverse clinical and laboratory characteristics, including course and laterality of AU; prevalence of positive results for PCR, GWC, or both; conjunctival redness; corneal edema; history of keratitis; presence of keratic precipitates; synechiae; heterochromia; and grade of inflammation.	21764137
Herpes Simplex Infections, Inflammation, herpesvirus 3, human, Vitritis	Altered Intercellular Communication	Herpes simplex virus AU often had severe anterior chamber inflammation, whereas the presence of vitritis was more common in RV AU and VZV AU.	21764137
Inflammation, Cerebrovascular accident, Chronic Kidney Diseases, Vascular calcification	Altered Intercellular Communication	Furthermore, relevant serum markers of inflammation, vascular calcification, and vessel wall degradation might be an indication of stroke risk in CKD patients.	21764239
Inflammation	Altered Intercellular Communication	Serum measurements of cytokines, mediators of various B and T cell activities, are important markers of inflammation and immune dysregulation.	21764327
Inflammation, Atherosclerosis	Altered Intercellular Communication	Among 221 genes involved in angiogenesis, inflammation and atherosclerosis, 24 were shown to be differentially modulated locally, by analysis with custom-designed DNA array technology.	21764664
Diabetes Mellitus, Non-Insulin-Dependent, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Predictive role of multilocus genetic polymorphisms in cardiovascular disease and inflammation-related genes on chronic kidney disease in Type 2 diabetes--an 8-year prospective cohort analysis of 1163 patients.	21765051
Inflammation, Kidney Diseases, Chronic Kidney Diseases	Altered Intercellular Communication	Seventy-seven single-nucleotide polymorphisms (SNPs) of 54 candidate genes for cardiorenal diseases and inflammation were genotyped in 1163 patients with no past history of CKD at baseline.	21765051
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Chronic Kidney Diseases	Altered Intercellular Communication	Risk associations with PON1, PON2, CETP, ITGA2 and LTA genetic polymorphisms underline the importance of lipid metabolism, haemostasis and inflammation in the development of CKD in patients with Type 2 diabetes.	21765051
Degenerative polyarthritis, Arthritis	Altered Intercellular Communication	Microarray analysis of the infrapatellar fat pad in knee osteoarthritis: relationship with joint inflammation.	21765106
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	To examine differences in genes involved in fat metabolism, energy homeostasis, adipogenesis, and inflammation between endstage and early-stage knee osteoarthritis (OA) infrapatellar fat pads (IFP).	21765106
Sepsis, Inflammation	Altered Intercellular Communication	However, systemic inflammation associated with sepsis, a common AKI-trigger, may affect cystatin C. We studied the impact of sepsis on cystatin C levels in plasma.	21765189
Disease, Arthritis, Pseudogout	Altered Intercellular Communication	The acute form of the disorder is referred as pseudogout, which can cause a severe joint inflammation.	21765235
Sepsis, Inflammation, Hypotension, CTCAE	Altered Intercellular Communication	Recently, kynurenine has been identified as an endothelium-derived relaxing factor produced during inflammation, raising the possibility that this novel pathway may contribute to hypotension in human sepsis.	21765346
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	The absence of this pattern in subjects with inflammatory bowel disease suggests it is not a sequel of inflammation or oxidative stress.	21766334
Inflammation, Anemia, Malignant Neoplasms	Altered Intercellular Communication	In 84 patients with advanced solid malignant tumors, but without iron or vitamin B12 and folate deficiency anemia, we measured serum pHp levels and common markers of iron status, erythropoiesis and inflammation.	21766512
Inflammation, Nia (fungus)	Altered Intercellular Communication	Lesions were classified into two groups based on the need for surgery and surgical findings: positive inflammation activity (PIA) and negative inflammation activity (NIA).	21767926
Parkinson Disease, palladium	Altered Intercellular Communication	Alpha-synuclein accumulation in intracellular inclusions, oxidative stress and microglia-mediated inflammation in the substantia nigra are crucial events in the pathogenesis of Parkinson's disease (PD).	21767974
Inflammation, Idiopathic osteoarthritis	Altered Intercellular Communication	We compared inflammation in the knee after total knee replacement (TKR) for primary osteoarthritis between two groups of patients undergoing joint replacement with and without synovectomy.	21768630
Inflammation, physiopathological, Diabetes Mellitus	Altered Intercellular Communication	HDL dysfunction associated with low-grade inflammation is a co-determinant of pre-diabetic states and their progression to diabetes.	21769500
Inflammation, Malignant Pleural Mesothelioma, Neoplasms	Altered Intercellular Communication	Chronic inflammation in tumor stroma is an independent predictor of prolonged survival in epithelioid malignant pleural mesothelioma patients.	21769693
Inflammation	Altered Intercellular Communication	In multivariate analysis, chronic inflammation in stroma was an independent predictor of survival (HR = 0.659, 95% CI 0.464-0.937, P = 0.02).	21769693
Inflammation, Atherosclerosis	Altered Intercellular Communication	Our study demonstrated that total WBC counts play an important role in inflammation and are associated with the presence, severity and extent of coronary atherosclerosis detected by MSCT.	21769817
Inflammation, Corneal edema	Altered Intercellular Communication	Although inflammation became quiescent within a month, corneal edema developed 4 months after insertion.	21770807
Inflammation	Altered Intercellular Communication	These results did not provide conclusive support for a hypothesis of a pathophysiological role of inflammation intracranially.	21771198
Inflammation, Postcholecystectomy Syndrome, Stenosis	Altered Intercellular Communication	Inadequate calculi removal, bile stasis, inflammation and strictures are causes of postcholecystectomy biliary syndrome.	21771404
Neurotransmitters, Depression, CTCAE	Altered Intercellular Communication	Testing homocysteine-induced neurotransmitter deficiency, and depression of mood hypothesis in clinical practice.	21771745
Neurotransmitters, Depression, CTCAE	Altered Intercellular Communication	high total plasma homocysteine (tHcy) levels may cause neurotransmitter deficiency, and consequently depression of mood.	21771745
Takotsubo Cardiomyopathy, Myocardial, Myocarditis, physiopathological	Altered Intercellular Communication	Stress cardiomyopathy was accurately identified by CMR using specific criteria: a typical pattern of LV dysfunction, myocardial edema, absence of significant necrosis/fibrosis, and markers for myocardial inflammation.	21771988
Virus Diseases, Hepatitis	Altered Intercellular Communication	The purpose of this study was to elucidate whether the expression of Foxp3 relates not to the viral infection but to the resulting liver inflammation.	21772667
Hepatitis	Altered Intercellular Communication	Our findings indicate that, independently of the initial inducer, liver inflammation is correlated with elevated expression of apoptosis mediators and is followed by local Treg accumulation.	21772667
Hepatosplenomegaly, Histiocytosis haematophagic, Lymphohistiocytosis, Hemophagocytic, Fever, CTCAE, Cytopenia	Altered Intercellular Communication	Hemophagocytic syndrome (HS) is a severe hyper inflammatory condition whose cardinal symptoms are prolonged fever, cytopenia, hepatosplenomegaly, and hemophagocytosis by activated, morphologically benign macrophages.	21773661
Inflammation	Altered Intercellular Communication	We hypothesized that body mass may affect DNA methylation through increased estrogen and chronic inflammation.	21775555
Inflammation, SSB gene, Rheumatoid Factor, Hypergammaglobulinemia	Altered Intercellular Communication	The laboratory findings showed high inflammation markers, rheumatoid factor 128 IU, Waaler-Rose 256 IU, anti nuclear antibody (ANA) 1/640, SSA (anti Sjogren antigen A) and SSB (anti Sjogren antigen B) positive and hypergammaglobulinemia.	21776446
Inflammation, Cardiovascular Diseases, Cancer-related fatigue, Dyslipidemias, Chronic Kidney Diseases	Altered Intercellular Communication	Dyslipidemia, oxidative stress (OS) and inflammation increase the risk of cardiovascular disease in chronic renal failure (CRF) patients.	21776461
Inflammation, Psoriasis, Cardiovascular Diseases	Altered Intercellular Communication	Psoriasis confers an independent risk of cardiovascular disease that is likely to be related to systemic inflammation.	21777216
Dermatomyositis, Inflammation, Dermatomyositis, Childhood Type, Gastrointestinal tract structure	Altered Intercellular Communication	Juvenile dermatomyositis (JDM) is an important subtype of dermatomyositis characterized by inflammation of muscle, skin and gastrointestinal tract.	21777536
Cell Death, Liver carcinoma, Inflammation, FAM126A gene	Altered Intercellular Communication	Development of hepatocellular carcinoma (HCC) is a complex and progressive disease that involves cycles of liver cell death, inflammation, and tissue regeneration/remodelling.	21778049
Airway structure, Wheezing	Altered Intercellular Communication	The functional outcome in preschool severe wheezers with eosinophilic airway inflammation and increased reticular basement membrane (RBM) thickness is unknown.	21778162
Inflammatory abnormality of the eye	Altered Intercellular Communication	Suppressor of cytokine signaling-1 (SOCS1) inhibits lymphocyte recruitment into the retina and protects SOCS1 transgenic rats and mice from ocular inflammation.	21778271
Inflammation, Fever, CTCAE, Empyema, Pleural	Altered Intercellular Communication	However, pyothorax developed, and in October, 2008 he was admitted again with fever and inflammation.	21778636
Low Back Pain, Inflammation	Altered Intercellular Communication	There was a rapid reduction of the left iliopsoas abscess, his inflammation and lumbago symptoms reduced, and he was discharged in January 2009.	21778636
Inflammation, Hypogonadism, Weight decreased, Osteopenia	Altered Intercellular Communication	Hypogonadism, weight loss, and chronic inflammation are other contributors to bone loss in a variety of disease states.	21778745
Inflammation, Nasal Polyps, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Additionally, eosinophilic chronic rhinosinusitis (ECRS) in Japan is considered to be a subgroup of CRS with nasal polyps (CRSwNP) characterized by eosinophil-dominant inflammation.	21778815
Tumor necrosis, Psoriasis	Altered Intercellular Communication	Tumor necrosis factor a antagonists are proven to be effective for the treatment of chronic inflammatory conditions, such as psoriasis.	21778902
Fibrosis Assessment, Hepatic inflammation, Fatty degeneration	Altered Intercellular Communication	Moreover, both ARFI and Fibroscan((r)) values increased in proportion to the severity of hepatic inflammation when fibrosis stage is low, but not in proportion to the severity of steatosis.	21779759
Chronic lymphocytic inflammation, Struma Ovarii	Altered Intercellular Communication	Authors report a case of a 52-year-old woman after struma ovarii with chronic lymphocytic inflammation excision.	21780949
Chronic lymphocytic inflammation	Altered Intercellular Communication	In histopatholgical examination struma ovarii with chronic lymphocytic inflammation was diagnosed.	21780949
Hashimoto Disease, Chronic lymphocytic inflammation, Struma Ovarii	Altered Intercellular Communication	In this case, an early diagnosis of Hashimoto disease resulted from excision of struma ovarii with chronic lymphocytic inflammation.	21780949
Inflammation, Anemia, idarubicin, Chronic disease	Altered Intercellular Communication	This audit reviewed red cell transfusion practice, degree of anaemia, iron deficiency anaemia (IDA) and chronic disease or anaemia of inflammation (AI) in cardiothoracic and orthopaedic surgical patients who had available iron studies.	21781124
Inflammation, Primary malignant neoplasm, Carcinoma, S100A4 protein, human	Altered Intercellular Communication	The presence of inflammatory reaction in peri-tumoural connective tissue is generally considered as a defense mechanism against cancer, but inflammation tissue in malignant transformation and early steps of oncogenesis has been recently proven to play a supporting and aggravating role in some carcinomas.	21781456
Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Currently, precise mechanisms of atrial fibrillation (AF) are uncertain but proved to be associated with inflammation.	21782262
Chronic inflammation	Altered Intercellular Communication	Further, there was an increase of immature collagen in the connective tissue, and signs of a mild chronic inflammation.	21783002
Inflammation, Dryness (characteristic)	Altered Intercellular Communication	Chronic inflammation, dryness of the gingiva, or even the minimal glycogen accumulation in the fibroblasts may have played a role.	21783002
Dystrophic calcification, Tonsillitis	Altered Intercellular Communication	Tonsilloliths are rare dystrophic calcifications caused by chronic inflammation of the tonsils.	21783100
vascular inflammations, Encephalomyelitis, Acute Disseminated	Altered Intercellular Communication	In this case, LCL is considered to be associated with ADEM, an acute autoimmune response to myelin, and vascular inflammation of the gray matter of the spinal cord.	21783334
Cerebral Amyloid Angiopathy, Inflammation, Hemorrhage, Vasculitis	Altered Intercellular Communication	The third VE case was associated with numerous microhemorrhages in keeping with cerebral amyloid angiopathy-related inflammation or Ab-related angiitis.	21784350
Allergic asthma, Inflammation, AHR wt Allele	Altered Intercellular Communication	Accordingly, we hypothesized that local aerosol delivery of GSNO could ameliorate AHR and inflammation in the ovalbumin-sensitized and -challenged (OVA) mouse model of allergic asthma.	21784966
Allergic asthma, Airway structure	Altered Intercellular Communication	In conclusion, in the OVA mouse model of allergic asthma, aerosolized GSNO has rapid and sustained antibronchoconstrictive effects but does not substantially alter airway inflammation.	21784966
airway disease, Inflammation, Asthma	Altered Intercellular Communication	Systemic inflammation is now recognised as an important part of some airway diseases, but the involvement of systemic inflammation in the pathogenesis of airway inflammatory phenotypes of asthma remains unknown.	21785157
Airway structure	Altered Intercellular Communication	Plasma elastase was significantly increased in people with neutrophilic airway inflammation.	21785157
Inflammation, Venous Thromboembolism, Heart failure, Malignant Neoplasms, Kidney Failure, Liver Cirrhosis, Acute infectious disease	Altered Intercellular Communication	Patients with acute infection, renal failure, heart failure, liver cirrhosis, chronic inflammation, venous thromboemboli, malignancies and pregnancy were excluded.	21785169
Inflammation, Juvenile polyposis syndrome	Altered Intercellular Communication	However, because CRP is a marker for systemic inflammation, this test is not specific to PJI.	21786056
Refractory anemias, Inflammation	Altered Intercellular Communication	The impact on the clinical situation and the RA severity regarding the inflammation was analyzed.	21786121
Renal Insufficiency, Acute inflammation, Nephritic syndrome, Impaired	Altered Intercellular Communication	Carriers of Pro allele more often have signs of active glomerular inflammation and vascular impairment with renal dysfunction while carriers of Arg/Arg genotype more frequently demonstrate isolated nephritic syndrome.	21786572
Tissue damage, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP) is a sensitive, non-specific systemic marker for inflammation and tissue damage in the human body and independently associated with incident cardiovascular disease (CVD) and traditional CVD risk factors.	21788019
Postherpetic neuralgia, Inflammation, Herpes zoster disease	Altered Intercellular Communication	Intraocular pressure, inflammation, steroid use, surgical procedures, anterior segment complications, post-herpetic neuralgia, and delayed herpes zoster pseudodendrites.	21788078
Inflammation, Keratitis, Keratopathy, Exacerbation of cGVHD	Altered Intercellular Communication	Younger patients had more episodes of delayed pseudodendritiform keratitis and flares of inflammation compared with older patients, who had more problems related to neurotrophic keratopathy.	21788078
Tumor necrosis, Inflammation	Altered Intercellular Communication	Etanercept blocks tumour necrosis factor (TNF)-a, which plays a central role in the psoriatic inflammation process.	21790728
Psoriasis	Altered Intercellular Communication	A combination of selected inflammatory factors (which we term the Index of Psoriasis Inflammation) in combination with PASI might reflect inflammatory status in psoriasis more accurately than each one separately.	21790728
Gastritis	Altered Intercellular Communication	According to endoscopic diagnosis, patients with gastric cardiac inflammation and BE were selected from March 2008 to February 2009 in Renji Hospital, Shanghai Jiaotong University School of Medicine.	21791021
Inflammation, Esophagitis	Altered Intercellular Communication	Inflammation in the gastric antrum was more severe in the CIM group (45.1% vs 26.6%), in contrast, esophagitis was more severe in the BE group (53.1% vs 35.4%).	21791021
Inflammation, Metabolic Diseases, Fibrosis Assessment	Altered Intercellular Communication	Adiponectin protects from inflammation and fibrosis in metabolic liver disease.	21791204
Inflammation, Fibrosis Assessment, Steatohepatitis	Altered Intercellular Communication	The current data indicate that in NASH hepatic inflammation and fibrosis but not hepatic steatosis induce liver MMP-9 activity, and this induction seems to be related to the anti-inflammatory activity of adiponectin rather than its effect on hepatocellular MMP-9 expression.	21791204
Inflammation, Lymphocytic infiltration, Ulcer	Altered Intercellular Communication	Gastroscopy revealed an ulcer with a suspicious malignant appearance, and histology of the endoscopic specimen showed severe chronic inflammation and lymphocytic infiltration.	21791308
Stable chronic Graft vs Host Disease, Inflammation, Fibrosis Assessment, Functional Disability	Altered Intercellular Communication	The sclerotic skin manifestations of cGVHD (ScGVHD) result from inflammation and fibrosis of the dermis, subcutaneous tissue, or fascia, leading to significant functional disability.	21791415
Granulomatous inflammation	Altered Intercellular Communication	The Surepath smear showed crowded cellular groups with abundant epithelioid histiocytes and lymphocytes consistent with granulomatous inflammation.	21791908
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	Uterine cervical sarcoidosis, although rare, can be an overlooked cause of non-necrotizing granulomatous inflammation in a cervical Pap test.	21791908
Sarcoidosis, Tuberculosis	Altered Intercellular Communication	Sarcoidosis should be a diagnosis of exclusion; other common conditions with similar morphologic presentation such as non-necrotizing tuberculosis, foreign body-related granulomatous inflammation, and neoplastic/chemotherapy-related sarcomatoid reaction need to be excluded in conjunction with the patient's clinical history.	21791908
vascular inflammations	Altered Intercellular Communication	AC13, a candidate biomarker for MPA, may be useful for monitoring disease activity and may exacerbate vascular inflammation through up-regulation of proinflammatory cytokines.	21792834
Inflammation	Altered Intercellular Communication	We report the case of a 2-week-old male who presented with a swollen, erythematous left index finger and elevated serum markers of inflammation.	21792839
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	These null findings might be due to methodological issues; however, it is unlikely that strong and long-lasting associations between inflammation and PCa risk were missed as this was a large database with long follow-up.	21792885
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Toll-like receptors (TLRs) are mediators of inflammation in the gut and potentially important modulators of colon and rectal cancer risk.	21792899
Inflammation, Swelling	Altered Intercellular Communication	In patients without a history of inflammation, aggressive massage of the swelling could produce abundant intraoral salivary flow.	21792955
Airway structure, Signs and Symptoms, Respiratory, Asthma, Pneumonia	Altered Intercellular Communication	Whether respiratory symptoms, lung function, and airway inflammation differ in asthmatic patients with and without a history of pneumonia remains controversial.	21793780
Inflammation	Altered Intercellular Communication	We found no differences among groups in metabolic and hormonal profile, serum antioxidant capacity, or inflammation (P > 0.05).	21795022
Inflammation	Altered Intercellular Communication	We found no differences among groups in metabolic and hormonal profile, serum antioxidant capacity, or inflammation (P > 0.05).	21795022
Inflammation, Brain Neoplasms	Altered Intercellular Communication	We predicted that T. gondii could increase the risk of brain cancer because it is a long-lived parasite that encysts in the brain, where it provokes inflammation and inhibits apoptosis.	21795265
Osteomyelitis, Inflammation, Cellulitis	Altered Intercellular Communication	From a total of 23 lesions, we observed 10 sites of osteomyelitis, 10 sites of cellulitis, and 3 sites of aseptic inflammation confirmed by MRI, clinical presentation, histopathologic examination, and follow-up evaluation as a gold standard.	21795373
Osteomyelitis, Inflammation, Cellulitis	Altered Intercellular Communication	There was no significant difference between the semiquantitative indices of 5-h and 24-h (99m)Tc-IgG scanning for inflammation, cellulitis, and osteomyelitis.	21795373
Inflammation, Acanthosis, Fibrosis Assessment	Altered Intercellular Communication	The histological scoring system showed a significant reduction of inflammation, no difference in fibrosis, and an increase of acanthosis.	21795984
Intestinal metaplasia, Helicobacter pylori, Chronic inflammation, Atrophic	Altered Intercellular Communication	All of the cases were evaluated according to the Sydney classification, and the relation of Helicobacter pylori with chronic inflammation, atrophy, intestinal metaplasia, and activity was investigated by two pathologists.	21796546
Intestinal metaplasia, Inflammation, Helicobacter pylori	Altered Intercellular Communication	Activity, inflammation and intestinal metaplasia were found in 10 (10%), 70 (70%) and 10 (10%) of Helicobacter pylori (-) patients, respectively, and the numbers increased with increasing Helicobacter pylori intensity when compared with Helicobacter pylori (+) patients (p<0.01, p<0.01 and p<0.05, respectively).	21796546
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	There was no significant difference between corpus alone or antrum alone Helicobacter pylori (+) and both corpus/antrum (+) patients in regards to the presence of activity, inflammation, intestinal metaplasia, and atrophy (p>0.05).	21796546
Intestinal metaplasia, Inflammation, Dyspepsia	Altered Intercellular Communication	As activity, inflammation and intestinal metaplasia increase with increasing Helicobacter pylori intensity in dyspepsia patients, Helicobacter pylori eradication treatment can be recommended in these patients.	21796546
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Shiftwork is associated with an increased risk of cardiovascular diseases, but the possible role of inflammation in this relationship is not well known.	21797781
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Our results suggest that 2- and 3-shift work is associated with increased systemic inflammation and the relationship is relatively independent of the considered risk factors of cardiovascular disease.	21797781
Inflammation, Pericardial Effusion, CTCAE, Fever, CTCAE, Pleuritic pain, Pleural Effusion, CTCAE	Altered Intercellular Communication	Specific symptoms, signs, or features were pleuritic chest pain (55.6%), fever (53.7%), elevated markers of inflammation (74.1%), pericardial effusion (88.9%), and pleural effusion (92.6%).	21798503
Inflammation, Psychotic Disorders	Altered Intercellular Communication	Inflammation in psychotic disorders: a population-based study.	21798602
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The expression of cyclooxygenase 2 (COX-2) is usually increased in inflammation and cancer.	21798652
Inflammation	Altered Intercellular Communication	However, there is virtually no data about the link between glucagon and inflammatory parameters in obesity-related chronic low-grade inflammation.	21798957
Inflammation	Altered Intercellular Communication	This suggests that glucagon may be behind the association between inflammatory and metabolic parameters in obesity-associated chronic low-grade inflammation.	21798957
Inflammation	Altered Intercellular Communication	Adrenomedullin (ADM) plays an important role in inflammation and is a marker of future cardiovascular events.	21798961
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Immune responses to brain antigens occur after stroke, and experimental studies show that the likelihood of developing a detrimental autoimmune response to these antigens is increased by systemic inflammation at the time of stroke.	21799171
Inflammation, Critical Illness	Altered Intercellular Communication	These results indicate that PAB may not be a sensitive marker for evaluating the adequacy of nutrition support in critically ill patients with inflammation.	21799187
Conjunctivitis	Altered Intercellular Communication	Patients with EOD were younger and had more severe conjunctival inflammation (76% of inflamed eyes) than the EstD group, who had poorer VA (26.7%=VA<3/60, P<0.01) and more advanced disease.	21799523
Epithelial Damage, Colitis	Altered Intercellular Communication	On the one hand, age-related telomere shortening and inflamm-ageing may lead to the development of colonic inflammation, which results in epithelial damage.	21799643
Epithelial Damage, Colitis	Altered Intercellular Communication	On the one hand, age-related telomere shortening and inflamm-ageing may lead to the development of colonic inflammation, which results in epithelial damage.	21799643
Vascular Diseases, Inflammation, Aortic Aneurysm, Abdominal, Behavioral and psychological symptoms of dementia, APP gene	Altered Intercellular Communication	Lower limb athero-thrombosis and abdominal aortic aneurysm (AAA) have both been previously associated with neuropsychiatric symptoms possibly due to associated intracerebral vascular disease or systemic inflammation, hence suggesting that these illnesses may be regarded as models to investigate the vascular genesis of neuropsychiatric symptoms.	21799922
Esophagitis	Altered Intercellular Communication	If patients have evidence of esophageal inflammation, they undergo esophagogastroduodenoscopy (EGD).	21800159
Esophagitis	Altered Intercellular Communication	For computed tomography (CT) scans, esophageal inflammation was scored from 0 to 2.	21800159
Esophagitis	Altered Intercellular Communication	The kappa score for the inter-rater agreement of esophageal inflammation on EGD was 0.4584 (moderate).	21800159
Esophagitis	Altered Intercellular Communication	There was no agreement between immediate imaging and the endoscopic findings of esophageal inflammation after AFA.	21800159
Inflammation	Altered Intercellular Communication	His blood test showed slightly elevated muscle enzyme activity, and magnetic resonance imaging suggested severe inflammation of the muscles.	21800697
Inflammation, Asthma	Altered Intercellular Communication	Systemic inflammation is suggested as a mechanism by which overweight might induce asthma.	21801245
Inflammation, Asthma, Overweight	Altered Intercellular Communication	However, few studies have linked childhood overweight, inflammation and asthma.	21801245
Airway structure, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	Upper airway inflammation and narrowing are characteristics of obstructive sleep apnoea (OSA).	21801324
Eruptions, Inflammation, Contusions	Altered Intercellular Communication	Postoperatively, severe contusion, inflammation, and erythematous vesicular eruption resulted in a lengthened hospital stay.	21801935
Inflammation, Aneurysm	Altered Intercellular Communication	Periaortic inflammation and aneurysms in the nonfistula group completely disappeared in 10 of the 15 patients (67%).	21802238
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	Sputum inflammation predicts exacerbations after cessation of inhaled corticosteroids in COPD.	21802933
Low Vision, Pain Distress Question, Chronic inflammation, Photophobia, Corneal Neovascularization	Altered Intercellular Communication	All 7 patients presented with severe loss of vision, photophobia, pain, chronic inflammation, and corneal vascularization and scarring.	21803325
Pain Distress Question, Photophobia, Inflammation	Altered Intercellular Communication	For 30 +- 19.8 months, pain and photophobia were resolved in all 7 eyes; 6 eyes exhibited a stable epithelium with regressed corneal vascularization and reduced chronic inflammation.	21803325
Cataract, Inflammation, Central heterochromia	Altered Intercellular Communication	Anterior segment manifestations included low-grade inflammation, posterior synechiae, reversible hyperchromic heterochromia, and a mature cataract with "leopard spots."	21803538
Inflammation	Altered Intercellular Communication	An orbital computed tomographic scan showed inflammation of the left orbital, preseptal, and retroseptal spaces.	21803720
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis near remission: clinical rather than laboratory inflammation is associated with radiographic progression.	21803751
Inflammation, Damage	Altered Intercellular Communication	In general, both contribute to the progression of joint damage, but the relevance of residual inflammation in patients near remission is unclear.	21803751
Inflammation, Malnutrition	Altered Intercellular Communication	Lower micronutrient intakes were associated with malnutrition and inflammation.	21804135
Inflammation, Diabetes Mellitus, Atherosclerosis	Altered Intercellular Communication	Standard serum markers of inflammation, diabetes, renal function, ankle-brachial indexes and traditional risk factors for atherosclerosis were noted and Fontaine classification was applied for the severity of symptoms.	21804488
Acute Coronary Syndrome	Altered Intercellular Communication	The altered expression of inflammation-related microRNAs with microRNA-155 expression correlates with Th17 differentiation in patients with acute coronary syndrome.	21804579
GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	In conclusion, our study revealed the expression patterns of inflammation-related miRNAs in patients with ACS and found that miR-155 may be associated with Th17 cell differentiation.	21804579
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Using the METAVIR score, advanced disease was defined as fibrosis stage >=F2, and active inflammation as grade >=A2.	21805422
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Markers useful for fibrosis prediction also predicted marked inflammation.	21805422
Myelofibrosis, Inflammation, Chronic myeloproliferative disorder, Primary Myelofibrosis, PMF Regimen, Thrombocytosis, Polycythemia Vera	Altered Intercellular Communication	Myeloproliferation, myeloaccumulation (decreased apoptosis), inflammation, bone marrow fibrosis and angiogenesis are cardinal features of the Philadelphia-negative chronic myeloproliferative neoplasms: essential thrombocythemia (ET), polycythemia vera (PV) and primary myelofibrosis (PMF).	21806350
Inflammation	Altered Intercellular Communication	The mechanism of the apparent increased inflammation with this combination remains under investigation.	21806360
Inflammation, Idiopathic chronic inflammatory bowel disease, Ulcerative Colitis	Altered Intercellular Communication	There has been controversy over the significance of active inflammation of the terminal ileum (also known as backwash ileitis) in patients with ulcerative colitis (UC) and idiopathic inflammatory bowel disease of indeterminate type for diagnosis and pouch construction.	21806956
Inflammation	Altered Intercellular Communication	Data from patients with backwash ileitis (n = 132) were compared with those from 132 matched controls without ileal inflammation for age, sex, and type of proctocolectomies with ileal pouch construction (1- or 2-stage).	21806956
Inflammation, Idiopathic chronic inflammatory bowel disease, Ulcerative Colitis	Altered Intercellular Communication	Ileal inflammation is not a contraindication for restorative proctocolectomy with ileal pouch construction in patients with UC or idiopathic inflammatory bowel disease of indeterminate type.	21806956
Inflammation, pancolitis, Ulcerative Colitis, Colitis	Altered Intercellular Communication	Ileal inflammation with pancolitis is not a useful criterion for classifying otherwise typical UC as colitis of indeterminate type, because pouch outcomes are not affected.	21806956
Inflammation, Chemical injury, Acute Cerebrovascular Accidents	Altered Intercellular Communication	The expression of soluble adhesion molecules inter-cellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1), besides activation of endothelial cells and transendothelial migration of leukocytes, play an important role in inflammation and progression of ischemic injury after acute stroke.	21808112
Inflammation	Altered Intercellular Communication	The observed a1-AT deficiency may be due to the chronic inflammation in TPE and associated oxidative stress.	21808138
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Lung Diseases, Obstructive	Altered Intercellular Communication	Asthma and chronic obstructive pulmonary disease (COPD) are characterised by airway and systemic inflammation, but little is known about differences and similarities in inflammatory markers in patients with obstructive airways disease.	21808940
Inflammation, Lung Diseases, Obstructive	Altered Intercellular Communication	Levels of serum hs-CRP, IgE, blood eosinophils, and FE(NO) identify distinct aspects of local and systemic inflammation in patients with obstructive airways disease.	21808940
Inflammation, immunoglobulin A	Altered Intercellular Communication	Chronic periodontit inflammation in old-aged patients was found to be accompanied by imbalance of complement system; sIgA, IgA, IgG and IgM hyperproduction; increased concentrations of IL-8, IL-1alpha and decreased level of IL-4; abrogated NO and its derivatives concentration; increased anti-HSP-70 and homocystein levels in blood and saliva.	21809634
Primary malignant neoplasm, Anemia	Altered Intercellular Communication	Neoadjuvant treatment should not be given to grave cases of rectal cancer with concomitant perifocal inflammation, anemia and advanced age.	21809661
Disease, Urinary Calculi, Ulcerative Colitis, Erectile dysfunction	Altered Intercellular Communication	Stone disease is associated with systemic metabolic and hormonal disorders that share common risk factors with erectile dysfunction (ED); however, few studies have investigated the association between ED and urinary calculi (UC).	21810186
Inflammatory Hepatocellular Adenoma, Non-alcoholic Fatty Liver Disease, Fatty degeneration, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	Mitochondrial dysfunction plays a central role in the general pathogenesis of non-alcoholic fatty liver disease (NAFLD), increasing the risk of developing steatosis and subsequent hepatocellular inflammation.	21810560
Inflammation	Altered Intercellular Communication	Single high-fat meals containing sequentially four different full-fat dairy foods did not increase eight circulating biomarkers related to inflammation or atherogenesis.	21811291
Inflammation, Venous Thrombosis, Chronic Lymphocytic Leukemia, Endothelial dysfunction	Altered Intercellular Communication	Inflammation, TNFa and endothelial dysfunction link lenalidomide to venous thrombosis in chronic lymphocytic leukemia.	21812019
Inflammation	Altered Intercellular Communication	Pseudomelanocytic nests in the setting of lichenoid inflammation can mimic atypical melanocytic proliferations.	21812802
Kidney Failure, Chronic, Thrombocytosis, Childhood Ataxia with Central Nervous System Hypomyelinization	Altered Intercellular Communication	We hypothesized that ESRD patients with relative thrombocytosis (platelet count >300 x 10(3)/mL) have a higher mortality rate and that this association may be related to malnutrition-inflammation cachexia syndrome (MICS).	21813809
Paresis, Myasthenia Gravis, Autoimmune Disorder, CTCAE	Altered Intercellular Communication	Myasthenia gravis (MG) is an autoimmune disorder characterized by a defect in synaptic transmission at the neuromuscular junction causing fluctuating muscle weakness with a decremental response to repetitive nerve stimulation or altered jitter in single-fiber electromyography (EMG).	21814823
Glaucoma, CTCAE, Vitreous inflammatory cells	Altered Intercellular Communication	Her right eye required goniosynechiolysis in order to cure a secondary glaucoma, and the left eye required vitrectomy in order to cure vitreous inflammation.	21815489
Sample Size Calculation, Inflammation	Altered Intercellular Communication	Hong Kong Chinese adults with SSc seem to exhibit higher levels of periodontal inflammation and wider radiographic periodontal ligament spaces than age- and sex-matched controls.	21815717
Refractory anemias, Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The duration of RA was associated with metabolic syndrome, implicating the role of inflammation in metabolic syndrome development.	21816020
Icterus, Cholecystitis	Altered Intercellular Communication	However, neither jaundice nor gallbladder inflammation was predictive of CDL in this study.	21816699
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation, as measured by the circulating inflammatory marker high-sensitivity C-reactive protein (hsCRP), has been associated with cardiovascular disease.	21816845
HMGCL gene, Inflammation, Edema, Pain Distress Question	Altered Intercellular Communication	Chief complaints of HL include inflammation, edema, pain, and reduced flexibility.	21816996
Cessation of life, Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD) is characterized by chronic inflammation, considered a nontraditional risk factor for cardiovascular disease, the major cause of death in CKD.	21817129
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	On-going airway inflammation is characteristic for the pathophysiology of chronic obstructive pulmonary disease (COPD).	21818276
Inflammation	Altered Intercellular Communication	Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort.	21818333
Psoriasis	Altered Intercellular Communication	Psoriasis is a chronic inflammatory condition that occurs worldwide; however, few studies have examined this condition in non-Caucasian populations.	21818507
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Depression and smoking: mediating role of vagal tone and inflammation.	21818530
Inflammation, Depression, CTCAE, Smoking	Altered Intercellular Communication	Smoking and depression are each associated with inflammation and vagal tone.	21818530
Inflammation, Cachexia, Cardiovascular Diseases	Altered Intercellular Communication	Wasting is common in hemodialysis patients and often is accompanied by cardiovascular disease and inflammation.	21820222
Sclerosis, Inflammation	Altered Intercellular Communication	Presently, OK-432 (Picibanil((r))) is the preferred sclerosant and when administered intralesionally will result in inflammation, sclerosis, and cicatricial contraction of the lesion.	21820291
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Red cell distribution width (RDW) is associated with morbidity and mortality in coronary artery disease (CAD), but the connection of RDW with chronic inflammation is equivocal.	21821014
Inflammation, Bipolar Disorder, Metabolic Syndrome X, Atherosclerosis	Altered Intercellular Communication	Depressive symptoms and sub-clinical atherosclerosis in Africans: role of metabolic syndrome, inflammation and sympathoadrenal function.	21821058
Inflammation, glycation	Altered Intercellular Communication	The calcium-binding protein S100A12 (EN-RAGE) causes inflammation through interaction with the multiligand receptor for advanced glycation end products (RAGE).	21822023
Inflammation, Decreased renal function	Altered Intercellular Communication	Although S100A12 levels were not elevated in patients with decreased kidney function, a relation to markers of inflammation was found.	21822023
vascular inflammations	Altered Intercellular Communication	Increased oxidative stress promotes vascular inflammation and is a common pathway involved in endothelial damage.	21822395
Inflammation	Altered Intercellular Communication	The time of exhibition suggests in parallel that the progressive increase of inflammation and/or oxidative stress plays a direct role in telomere shortening.	21824049
Bronchitis	Altered Intercellular Communication	One case of non-asthmatic eosinophilic bronchitis due to methylene diphenil isocyanates has been reported, but a similar condition in the instance of neutrophilic bronchial inflammation has never been described.	21824062
Asthma, Occupational, Bronchitis	Altered Intercellular Communication	The results of our case suggest that the occurrence of a neutrophilic bronchial inflammation without the functional characteristics of occupational asthma as a consequence of exposure to toluene diisocyanate may also be considered, suggesting a diagnosis of occupational non-asthmatic neutrophilic bronchitis.	21824062
Inflammation, Dyssomnias, Behavioral Symptoms, Breast Carcinoma, Depression, CTCAE, Fatigue	Altered Intercellular Communication	Inflammation and behavioral symptoms after breast cancer treatment: do fatigue, depression, and sleep disturbance share a common underlying mechanism?	21825266
Dyssomnias, Depression, CTCAE, Fatigue	Altered Intercellular Communication	Results also suggest that fatigue, sleep disturbance, and depression may stem from distinct biologic processes in post-treatment survivors, with inflammatory signaling contributing relatively specifically to fatigue.	21825266
Inflammation, Hemorrhage, Attachment (action), Periodontitis	Altered Intercellular Communication	Based on gum inflammation, bleeding on probing, periodontal pocket depth and attachment loss, patients were further divided into mild, moderate and severe periodontitis groups.	21826136
Inflammation, Neoplasms	Altered Intercellular Communication	Inflammation is a component of tumour progression mechanisms.	21826665
Inflammation, Urinary Bladder Diseases	Altered Intercellular Communication	Increased serum and urinary NGF levels in patients with OAB refractory to antimuscarinic treatment suggest these bladder disorders might be caused by chronic inflammation.	21826717
Inflammation, Erythema, Lymphedema	Altered Intercellular Communication	The scrotum was minimally tender, with an intact skin bereft of erythema or inflammation, lower limb lymphedema, inguinal/crural lymphadenopathy.	21826882
Gingivitis, Dental Plaque	Altered Intercellular Communication	Individuals with regular dental visits retained more teeth but the frequency of dental visits had no impact on plaque deposits, gingival inflammation, or alveolar bone levels.	21827016
Inflammation, melanoma	Altered Intercellular Communication	Since fistulae experience persistent inflammation, the fact that this melanoma harbours a BRAF mutation strengthens the view that oxidative stress caused by inflammatory processes plays an important role in the genesis of BRAF gene mutations.	21827678
Inflammation, Lung Diseases, Interstitial, Lung diseases, Carcinoma of lung	Altered Intercellular Communication	Inflammation and pulmonary diseases, including interstitial lung diseases, are associated with increased lung cancer risk.	21828236
Bipolar Disorder	Altered Intercellular Communication	This observation remained unaltered after additional adjustments for chronic inflammation-related disorders, the use of inflammation-modulating medications and depressive symptoms.	21829048
Inflammation, Obesity, Atherosclerosis	Altered Intercellular Communication	Obesity modifies the association between plasma phospholipid polyunsaturated fatty acids and markers of inflammation: the Multi-Ethnic Study of Atherosclerosis.	21829163
Disease, Inflammation, Obesity, Atherosclerosis	Altered Intercellular Communication	Systemic inflammation is a well-known risk factor for diseases such as atherosclerosis and is augmented by the presence of obesity.	21829163
Inflammation, Asthenia, Deglutition Disorders, Swallowing painful	Altered Intercellular Communication	Mucosal inflammation, asthenia, odynophagia, and dysphagia were the most commonly reported adverse events with lapatinib.	21829197
Inflammation	Altered Intercellular Communication	Renal patients were characterized by higher OS and inflammation than healthy subjects.	21829457
TG gene, Inflammation	Altered Intercellular Communication	Inflammation correlated strongly with TG, VLDL-cholesterol, apolipoprotein (apo) C-III and apoC-III bound to apoB-containing lipoproteins, but not with either total cholesterol or LDL-cholesterol.In conclusion, we have discovered a new inflammatory factor, TG48.	21829457
Inflammation, In-Stent Restenosis Indicator	Altered Intercellular Communication	Inflammation and in-stent restenosis: the role of serum markers and stent characteristics in carotid artery stenting.	21829478
Vascular System Injuries	Altered Intercellular Communication	Our findings support the assumption that stent geometry leading to vessel injury as well as periprocedural inflammation during CAS plays a pivotal role in the development of carotid artery ISR.	21829478
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Matrix metalloproteinase 13 (MMP13) can degrade fibrillar collagens and elastic microfibrils, and is involved in inflammation and fibrosis.	21830104
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Synovial fibroblasts (SFs) contribute to the development of osteoarthritis (OA) by the secretion of a wide range of pro-inflammatory mediators, including cytokines and lipid mediators of inflammation.	21830213
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Previous studies suggest that electromagnetic fields (EMFs) may represent a potential therapeutic approach to limit cartilage degradation and control inflammation associated to OA, and that they may act through the adenosine pathway.	21830213
Inflammation, Arthropathy	Altered Intercellular Communication	Taken together, these results open new clinical perspectives to the control of inflammation associated to joint diseases.	21830213
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Given the accumulating evidence for an important role of PXR in intestinal inflammation, further analyses are required to investigate the functional and pharmacogenetic implications of these PXR/NR1I2 gene variants in IBD.	21830270
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	We speculate that aging, rather than inflammation per se, promotes CIMP(+) CRCs in IBD patients.	21830278
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Chronic heart failure (CHF) is associated with increased inflammation, and exercise training has in some studies been shown to have anti-inflammatory effect, although controversies exist.	21831004
Inflammation, Congestive heart failure	Altered Intercellular Communication	Measures of CHF severity were significantly correlated with several markers of inflammation.	21831004
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The TGF-b superfamily cytokine, MIC-1/GDF15: a pleotrophic cytokine with roles in inflammation, cancer and metabolism.	21831009
Inflammation, Primary malignant neoplasm, Cardiovascular Diseases	Altered Intercellular Communication	Macrophage inhibitory cytokine-1 (MIC-1/GDF15) is associated with cardiovascular disease, inflammation, body weight regulation and cancer.	21831009
Primary malignant neoplasm, Chronic inflammation, Obesity	Altered Intercellular Communication	Available data suggest MIC-1/GDF15 may be an important molecule mediating the interplay between cancer, obesity and chronic inflammation.	21831009
palladium, Inflammation	Altered Intercellular Communication	Inflammation may be one possible pathway to link PD with CVD.	21831372
Inflammation, Ectopic kidney	Altered Intercellular Communication	The CTA revealed significant thickening of the aortic wall, suggestive of aortic inflammation, the presence of crossed renal ectopia with fusion, and numerous anomalous renal arteries.	21831590
Inflammation, Aneurysm	Altered Intercellular Communication	Given the aortic inflammation, an open repair approach was considered high risk compared with an endovascular aneurysm repair (EVAR).	21831590
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide (ENO) is used as a marker of airway inflammation.	21832821
Inflammatory Bowel Diseases, CDISC Integrated Basic Data Structure Dataset, Ulcerative Colitis, Crohn Disease, Inflammation of large intestine	Altered Intercellular Communication	Inflammatory bowel diseases (IBDs), Crohn's disease, and ulcerative colitis (UC), are multifactorial disorders, characterized by chronic inflammation of the intestine.	21832969
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Our study adds DBP to the list of potential genes that contribute to the complex genetic etiology of IBD, and further emphasizes the association between vitamin D homeostasis and intestinal inflammation.	21832969
Inflammation, Aortic Stiffness	Altered Intercellular Communication	Aortic stiffness, inflammation, denutrition and prognosis in the oldest people.	21833025
Inflammation, Lupus Erythematosus	Altered Intercellular Communication	Arterial stiffening, wave reflection, and inflammation in habitually exercising systemic lupus erythematosus patients.	21833040
Inflammation, Hypertension, CTCAE, Cardiovascular Diseases	Altered Intercellular Communication	Chronic systemic inflammation has been implicated in the pathogenesis of hypertension and cardiovascular disease.	21833040
Inflammation, Lupus Erythematosus, Systemic, Autoimmune Diseases, Cardiovascular Diseases, Lupus Erythematosus	Altered Intercellular Communication	Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by chronic inflammation and an increased risk for cardiovascular disease.	21833040
Arterial Stiffness, Inflammation	Altered Intercellular Communication	Furthermore, greater arterial stiffness was associated with higher inflammatory markers, suggesting that need for studies on inflammation and SLE-associated arterial stiffening.	21833040
Inflammation, NLRP3 gene	Altered Intercellular Communication	FCAS results in cold-induced cytokine dysregulation and systemic inflammation.	21833523
Inflammation	Altered Intercellular Communication	Chronic inflammation: a poor prognostic factor for endoscopic dacryocystorhinostomy.	21833563
Inflammation, Fibrosis Assessment, Leucocytic infiltrate	Altered Intercellular Communication	All the specimens were examined for the chronic inflammation related histopathological features (inflammatory cell infiltration, fibrosis and capillary proliferation) and graded according to their severity.	21833563
Inflammation	Altered Intercellular Communication	However, 9 of 10 patients with unsatisfactory and/or unsuccessful outcome (90%) had severe chronic inflammation of lacrimal sac.	21833563
Inflammation, Fibrosis Assessment, Leucocytic infiltrate	Altered Intercellular Communication	In subjective assessment, inflammatory cell infiltration (p = 0.050), fibrosis (p = 0.037), capillary proliferation (p = 0.007) and chronic inflammation (p = 0.003) had a statistically significant difference between patients with satisfactory and unsatisfactory outcome.	21833563
Inflammation, Leucocytic infiltrate	Altered Intercellular Communication	In objective assessment, statistically significant differences were detected between patients with successful and unsuccessful outcome when they compared according to inflammatory cell infiltration (p = 0.027), capillary proliferation (p = 0.007) and chronic inflammation (p = 0.003).	21833563
Inflammation	Altered Intercellular Communication	Chronic inflammation related histopathological features of variable degree may have a role on En-DCR outcome.	21833563
Inflammation	Altered Intercellular Communication	Furthermore, gadolinium-enhanced inflammation on brain MRI rapidly disappeared after CBT.	21834803
Cessation of life, Inflammation	Altered Intercellular Communication	We have previously demonstrated that glia maturation factor (GMF), a brain-specific protein, isolated, sequenced, and cloned in our laboratory, is a prominent mediator of inflammation in the CNS leading to the death of neurons.	21835226
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	dal-PLAQUE will provide important information on the effects of dalcetrapib on markers of inflammation and atherosclerotic plaque burden and, thereby, on the safety of cholesteryl ester transfer protein modulation with dalcetrapib.	21835280
Malignant neoplasm of ovary, Pelvic Inflammatory Disease	Altered Intercellular Communication	Whether pelvic inflammation itself accelerates the growth of ovarian cancers or affects cancer-cell differentiation in ways that adversely alter prognosis needs to be investigated.	21835693
Communicable Diseases, Pancreatic stone, Inflammation	Altered Intercellular Communication	Pancreatic stone protein (PSP)/regenerating protein (reg) is associated with inflammation, infection, and other disease-related stimuli.	21835904
Inflammation	Altered Intercellular Communication	To conclude, retained PFCL can cause late onset fibrinous inflammation after a quiescent period but surgical intervention may lead to good visual outcome.	21836352
Inflammation, Lymphadenopathy	Altered Intercellular Communication	We describe a patient who presented with cervical and inguinal lymphadenopathies and high inflammation indexes.	21837920
Inflammation	Altered Intercellular Communication	Ruptured intraneural cysts and simple cysts share these MRI findings: T2 hyperintense fluid within surrounding intermuscular fascial planes and enhancement with intravenous contrast consistent with inflammation.	21838077
Inflammation, Steatohepatitis	Altered Intercellular Communication	Visceral fat differs from subcutaneous fat by higher local inflammation and increased release of IL-6 and free fatty acids (FFA) which contribute to hepatic steatosis.	21839737
Inflammation, Apolipoprotein E	Altered Intercellular Communication	Apolipoprotein E is associated with blood lipids and inflammation in Taiwanese older adults.	21840004
Lysosomal Storage Diseases, Inflammation, Globoid cell leukodystrophy	Altered Intercellular Communication	One of a family of devastating lysosomal storage disorders, Krabbe disease is characterized by demyelination, psychosine accumulation, and inflammation.	21840342
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation is a major factor underlying acute coronary syndromes (ACS).	21840418
GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	HDL particles may be remodeled, becoming functionally defective, under the inflammatory conditions seen in ACS.	21840418
Meningitis	Altered Intercellular Communication	Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis.	21840891
Meningitis	Altered Intercellular Communication	Meningeal inflammation in the form of ectopic lymphoid-like structures has been suggested to play a prominent role in the development of cerebral cortical grey matter pathology in multiple sclerosis.	21840891
Meningitis	Altered Intercellular Communication	The presence of B cell follicle-like structures was associated with an accompanying quantitative increase in diffuse meningeal inflammation that correlated with the degree of microglial activation and grey matter cortical demyelination.	21840891
Inflammation, Psoriasis, Atrial Fibrillation by ECG Finding, Ischemic stroke, Chronic inflammatory disorder, Atrial Fibrillation	Altered Intercellular Communication	Psoriasis is a chronic inflammatory disease and inflammation contributes to the pathogenesis of atrial fibrillation (AF) and ischaemic stroke.	21840930
dendritic lamellar body, Data types - Address	Altered Intercellular Communication	We retrospectively compared CSF concentrations of the neurotransmitter metabolites homovanillic acid (HVA), 5-hydroxyindolacetic acid (5-HIAA), and 3-methoxy-4-hydroxyphenylethyleneglycol (MHPG) and the brain-specific proteins total tau (t-tau), phosphorylated tau protein (p-tau), and amyloid-b42 (Ab42) in 45 patients with AD (mean age 71.6 years; 34 (76%) men; 44 probable AD, 1 definite) and 23 patients with DLB (mean age 71.6 years; 18 (78%) men; 6 possible DLB, 16 probable, 1 definite).	21841257
dendritic lamellar body, Data types - Address	Altered Intercellular Communication	The concentrations of all neurotransmitter metabolites, as well as those for t-tau and p-tau protein, were significantly lower in DLB compared to AD, irrespective of the diagnostic certainty (i.e., possible or probable).	21841257
Communicable Diseases, Chlamydia, Inflammation, Coronary Artery Disease	Altered Intercellular Communication	We evaluated the role of inflammation and acute or persistent Chlamydia pneumoniae infection in coronary artery disease (CAD).	21841301
Inflammation, Neoplasms, Tissue damage, Infection, Irritation	Altered Intercellular Communication	Although hypotheses about altered wound healing mechanisms, influence of chronic inflammation and irritation or tissue damage through infections are conclusive, further investigations are necessary to clarify the exact pathogenetic mechanisms of tumour development in chronic wounds.	21841717
Inflammation, Edema, Conjunctival hyperemia	Altered Intercellular Communication	Light microscopy revealed decreased edema, fibrin deposition, inflammation and vascular congestion in the trabecular meshwork in specimens with IVB compared to those without IVB.	21842129
Intraocular inflammation, Uveitis	Altered Intercellular Communication	The synthetic peptides were tested against sera of 110 patients with different uveitis forms, classified according to anatomical location of intraocular inflammation.	21842131
Colitis, Ischemic, Colitis	Altered Intercellular Communication	Ischaemic colitis (IC) is an inadequate perfusion leading to potentially life-threatening colonic inflammation.	21842142
Inflammation	Altered Intercellular Communication	Limited information exists, however, regarding the relationship between low-grade inflammation and cognitive function in healthy older adults.	21843630
Inflammation, Pseudomonas aeruginosa	Altered Intercellular Communication	These microorganisms were associated with increased levels of inflammation, with P. aeruginosa being the most proinflammatory.	21844026
Multiple Organ Failure, Pneumonitis	Altered Intercellular Communication	Mixed oral flora (MOF) alone was isolated from 165 BAL samples from 112 patients, with 97 of these samples having a bacterial density >=10(5) cfu/mL, and was associated with increased pulmonary inflammation (P < .001).	21844026
Refractory anemias, Rheumatoid Arthritis, Inflammation, Atherosclerosis	Altered Intercellular Communication	We examined the hypothesis that cystatin C, a novel marker of renal function, is elevated in rheumatoid arthritis (RA) and is associated with inflammation and coronary atherosclerosis.	21844147
Refractory anemias, Inflammation, Renal Insufficiency	Altered Intercellular Communication	Cystatin C concentrations are higher in RA than controls and may reflect inflammation and undetected subclinical renal dysfunction.	21844147
Abnormality of the maxillary sinus, Nasal inflammation	Altered Intercellular Communication	Maxillary sinus abnormalities were demonstrated to be associated with maxillary sinus infundibulum narrowing as well as nasal airflow resistance secondary to nonspecific nasal inflammation.	21846296
Inflammation	Altered Intercellular Communication	Fat mass (FM) in overweight/obese subjects has a primary role in determining low-grade chronic inflammation and, in turn, insulin resistance (IR) and ectopic lipid storage within the liver.	21846339
Inflammation, Federated States of Micronesia, Obesity	Altered Intercellular Communication	Obesity, aging, and FM influence the growth hormone/insulin-like growth factor (IGF)-I axis, and chronic inflammation might reduce IGF-I signaling.	21846339
Inflammation, Federated States of Micronesia	Altered Intercellular Communication	We tested the hypothesis that FM, or spleen volume and C-reactive protein (CRP)--all indexes of chronic inflammation--could affect the IGF-I axis status in overweight/obese, independently of HS.	21846339
Inflammation, Federated States of Micronesia, Obesity	Altered Intercellular Communication	Obesity, aging, and FM influence the growth hormone/insulin-like growth factor (IGF)-I axis, and chronic inflammation might reduce IGF-I signaling.	21846339
Inflammation, Infection, Diabetes Mellitus	Altered Intercellular Communication	Likewise, chronic inflammation or infections seem to provoke insulin resistance and thereby contribute to the development of diabetes and its complications.	21848608
Chronic lymphocytic inflammation, Pontine structure, Clippers	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a recently defined inflammatory central nervous system disorder responsive to steroids with characteristic magnetic resonance imaging (MRI) features.	21848680
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Rapid resolution of symptoms and endoscopic inflammation in ulcerative colitis (UC) represent important treatment goals.	21848857
Proteinuria, Inflammation	Altered Intercellular Communication	We prospectively examined the relationships of WBC count, as a marker of inflammation, with two outcomes: proteinuria and low estimated glomerular filtration rate (eGFR).	21849773
Inflammation, Diabetic Retinopathy	Altered Intercellular Communication	High-mobility group box-1 and biomarkers of inflammation in the vitreous from patients with proliferative diabetic retinopathy.	21850157
Inflammation, PDR gene	Altered Intercellular Communication	Subclinical chronic inflammation might contribute to the progression of PDR.	21850157
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Xanthogranulomatous inflammation (XGI) is a special type of inflammation presenting as mass lesions and mimicking malignant tumors.	21850556
Inflammation, Myositis	Altered Intercellular Communication	Our observations that p75NTR is upregulated on skeletal myofibres in inflammatory myopathies in vivo and promotes resistance to inflammatory mediators in vitro suggest that neurotrophin signalling through p75NTR may mediate a tissue-protective response to inflammation in skeletal myofibres.	21851375
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Thrombophilia	Altered Intercellular Communication	Impaired glucose metabolism and type 2 diabetes are associated with hypercoagulability: potential role of central adiposity and low-grade inflammation--the Hoorn Study.	21851966
Immunoglobulin M, Inflammation, square decimeter	Altered Intercellular Communication	Individuals with IGM or DM2 had up to 4% higher thrombin generation compared with NGM, which may be explained, to a great extent, by the greater levels of central adiposity and related low-grade inflammation characterizing these individuals.	21851966
Peripheral Vascular Diseases, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Anti-endothelial cell antibodies are associated with peripheral arterial disease and markers of endothelial dysfunction and inflammation.	21852269
Steatohepatitis, Inflammation, Meibomian gland dysfunction	Altered Intercellular Communication	Increased visceral fat, as opposed to subcutaneous/gluteal, most strongly relates to key metabolic dysfunctions including insulin resistance, hepatic steatosis, and inflammation.	21852815
Crohn Disease, Inflammation, Hypertrophy	Altered Intercellular Communication	Mesenteric fat hypertrophy in patients with Crohn's disease and in experimental rodent models of gut inflammation suggest that impaired gut barrier function with increased leakage of gut-derived antigens may drive visceral lipid deposition.	21852815
Presenile dementia, Inflammation, Impaired cognition	Altered Intercellular Communication	Inflammation may contribute to cognitive decline and dementia.	21853262
Cognition Disorders, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Thus, markers of systemic inflammation are related to cognitive deficits in a non-clinical community-dwelling elderly population, independent of depression, cardiovascular or metabolic risk factors, or presence of apolipoprotein e4 genotype.	21853262
Inflammation	Altered Intercellular Communication	A time later, after complete remittance of local inflammation, the pancreas was anastomosed to the jejunum.	21853755
Inflammation	Altered Intercellular Communication	No reaction of ophthalmic inflammation was reported 5 days after injection, moreover foreign body sensation and bloodshot were absent.	21853949
HIV Antigens, Toxic effect	Altered Intercellular Communication	Although traditional risk factors of aging as well as treatment toxicity contribute to this risk, many investigators consider chronic HIV-associated inflammation a significant factor in such end-organ disease.	21854232
Inflammation, Psychological suppression	Altered Intercellular Communication	Despite effective viral suppression, chronic inflammation persists at levels higher than in uninfected people, yet the stimuli for the inflammation and the mechanism by which inflammation persists and promotes disease pathology remain incompletely understood.	21854232
Inflammation, Erythema, Hematoma	Altered Intercellular Communication	Redness and induration at the site of injection are commonly reported and are considered to be the result of local inflammation or hematoma formation, although other atypical reactions can occur.	21854416
Inflammation	Altered Intercellular Communication	The level of detected HBV-DNA-particles was low, however, indicating that the HBV infection alone could not be responsible for the inflammation.	21854665
Excessive tearing, Inflammation, Erythema, Pain Distress Question	Altered Intercellular Communication	nasolacrimal sac inflammation, characterised by epiphora, pain, erythema, sac dilation and lacrimal punctum swelling).	21854672
Extrinsic allergic alveolitis, Bronchiolitis Obliterans, histiocytic, Fibrosis Assessment	Altered Intercellular Communication	Histopathologic features assessed in each case included those characteristic of subacute hypersensitivity pneumonitis (bronchiolocentric chronic inflammation, histiocytic aggregates, and bronchiolitis obliterans), those associated with acute inflammation (fibrin deposition and neutrophilic infiltrate), and fibrosis.	21855112
Extrinsic allergic alveolitis, Granulomatous inflammation	Altered Intercellular Communication	Increased fibrin deposition and neutrophilic infiltrate may characterize acute hypersensitivity pneumonitis or abrupt exacerbation of hypersensitivity pneumonitis, and these along with characteristic features of subacute hypersensitivity pneumonitis (granulomatous inflammation and bronchiolocentricity) are sufficient to establish a morphologic diagnosis, particularly in conjunction with clinicoradiologic features.	21855112
ARCN1 gene, Inflammation, Blood Cells	Altered Intercellular Communication	Novel pharmacological strategies are aimed at the resolution of systemic inflammation in COPD potentiating peripheral blood T-cell (PBT-cell) apoptosis.	21855166
Airway structure, ARCN1 gene	Altered Intercellular Communication	Although muscarinic acetylcholine receptors (mAChRs) M(3) and choline-acetyltransferase (ChAT) participate in the airway inflammation of COPD, their role in PBT-cell apoptosis remains unexplained.	21855166
ARCN1 gene, Inflammation	Altered Intercellular Communication	It provides novel putative pharmacological targets for the resolution of systemic inflammation in COPD.	21855166
Inflammation, Myositis, CTCAE 5.0, Idiopathic Inflammatory Myopathies, Polymyositis, Heat-Shock Response, Dermatomyositis, Muscular Dystrophy, Duchenne	Altered Intercellular Communication	We examined the effects of chronic inflammation on the distribution of heat shock protein families 70 and 90 using immunofluorescence and Western blotting, in muscle biopsies from 33 idiopathic inflammatory myopathy patients [aged 26-66 (dermatomyositis), 17-78 (polymyositis) and 57-80 (sporadic inclusion body myositis) years], and seven Duchenne muscular dystrophy patients (aged 3-19 years).	21855341
Inflammation, Myopathy, Myositis, CTCAE 5.0	Altered Intercellular Communication	Sporadic inclusion body myositis (IBM) is a muscle disease with two separate pathogenic components, degeneration and inflammation.	21855683
Cataract, Intraocular inflammation, Edema	Altered Intercellular Communication	Single perioperative subconjunctival steroid depot versus postoperative steroid eyedrops to prevent intraocular inflammation and macular edema after cataract surgery.	21855759
Airway structure	Altered Intercellular Communication	The mechanism is unclear, but the effect may be mediated through induced airways inflammation.	21856701
Inflammation, Obesity	Altered Intercellular Communication	Adenosine, an endogenous anti-inflammatory metabolite, is increased in response to inflammation produced by adipose tissue in obesity.	21859364
Granulomatous inflammation, Sarcoidosis, Myocarditis, CTCAE 5.0, Giant cell myocarditis	Altered Intercellular Communication	We observed marked reduction in immunoreactive signal for plakoglobin at cardiac myocyte junctions in patients with sarcoidosis and giant cell myocarditis, both highly arrhythmogenic forms of myocarditis associated with granulomatous inflammation.	21859801
Inflammation, Chronic somatic dysfunction, Endothelial dysfunction	Altered Intercellular Communication	Oxidative stress may provide a link between endothelial dysfunction, inflammation, and immune activation and the development of chronic venous dysfunction.	21860369
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Retroperitoneal fibrosis (RPF) is a rare disease with unclear etiology, which is characterized by chronic non-specific inflammation of the retroperitoneum.	21860546
Hypophysitis, CTCAE, Inflammation, Autoimmune Diseases	Altered Intercellular Communication	Hypophysitis is a chronic inflammation of the pituitary gland often caused by autoimmunity.	21861119
Inflammation, Diabetes Mellitus, Endothelial dysfunction, Coronary heart disease	Altered Intercellular Communication	The greater adverse influence of diabetes per se on adiposity and HOMA-IR and downstream blood pressure, lipids, endothelial dysfunction and systemic inflammation in women compared with men may contribute to their greater relative risk of coronary heart disease.	21861177
Uveitis	Altered Intercellular Communication	All French rheumatologists, pediatric rheumatologists, and internal medicine practitioners registered on the Club Rhumatismes et Inflammation web site were contacted in an attempt to declare the cases of new onset of uveitis, diagnosed by an ophthalmologist, in patients treated with TNF blockers.	21862108
Cessation of life, Cardiac dysfunction	Altered Intercellular Communication	While elevated BNP, an abnormality of cardiac neurohormones, is known to be an independent marker of death or re-admission, it remains to be clarified whether there is also a strong predictor directly related to cardiac dysfunction.	21862290
Inflammation	Altered Intercellular Communication	Four patients showed clinical resolution of DS (no inflammation) after PDT sessions, and only 1 subject demonstrated reduction in palatal inflammation.	21862363
Inflammation, Trauma, Nervous System	Altered Intercellular Communication	Although intraneural injections have not resulted in clinically detectable neurologic injury in small studies in human subjects, intraneural injections result in postinjection inflammation in animal models.	21862889
Granulomatous inflammation, Chorioamnionitis, Pneumonia	Altered Intercellular Communication	Following elective pregnancy termination, microscopic examination and molecular analysis demonstrated Candida lusitaniae chorioamnionitis and pneumonia in all 3 fetuses associated with granulomatous inflammation.	21864122
Necrotizing granulomatous inflammation, Infective pneumonia acquired prenatally	Altered Intercellular Communication	We also show here that C. lusitaniae can cause granulomatous intraplacental inflammation and intrauterine pneumonia.	21864122
Inflammation	Altered Intercellular Communication	Zingiber officinale and Glycyrrhiza uralensis are found to have the ability to reduce pro-inflammatory cytokine production, to inhibit lipopolisaccharide-induced macrophage activation and function, and to lessen the bacterial load and suppress acute and chronic inflammation.	21864392
Inflammation, Overweight	Altered Intercellular Communication	Increasing the vegetable intake dose is associated with a rise in plasma carotenoids without modifying oxidative stress or inflammation in overweight or obese postmenopausal women.	21865569
Inflammation, Overweight	Altered Intercellular Communication	We conducted a 3-dose, crossover feeding trial to test the hypothesis that vegetable intake is associated in a dose-dependent manner with increased plasma carotenoids and subsequently reduced oxidative stress and inflammation in 49 overweight, postmenopausal women.	21865569
Inflammation, Ischemia	Altered Intercellular Communication	In the AMI setting, AF is frequently brief and attributed to acute haemodynamic changes, inflammation or ischaemia.	21866303
Heart failure, Hypoalbuminemia	Altered Intercellular Communication	Hypoalbuminemia is a common condition in patients with heart failure and is mainly related to the malnutrition-inflammation complex syndrome.	21867985
Inflammation, Myocardial, Heart failure, Hypoalbuminemia, Fluid overload	Altered Intercellular Communication	Hypoalbuminemia may also contribute to the progression of heart failure by favoring myocardial edema, volume overload, diuretic resistance and exacerbation of oxidative stress and inflammation.	21867985
Autoimmune Diseases, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Gonadotropin releasing hormone agonists may minimize cyclophosphamide associated gonadotoxicity in SLE and autoimmune diseases.	21868068
Hyperlipidemia, No metabolic abnormalities, Inflammation, Obesity	Altered Intercellular Communication	In particular, no single agent can correct multiple metabolic abnormalities such as insulin resistance, hyperlipidemia, inflammation, obesity, and fat distribution.	21869685
Inflammation, Autoinflammatory disorder, Fever, CTCAE, Tumor necrosis, Periodic Fever Syndrome, Trap medical device	Altered Intercellular Communication	Tumor necrosis factor receptor-associated periodic fever syndrome (TRAPS) is a rare systemic autoinflammatory disorder characterized by recurrent episodes of fever and localized inflammation of different organs.	21869706
Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	Low-grade inflammation and endothelial dysfunction may play a role in the pathogenesis of type 2 diabetes and cardiovascular disease.	21870174
Inflammation, Endothelial dysfunction, Overweight, Diabetes Mellitus	Altered Intercellular Communication	Our results suggest that the combined effect of fatty fish, bilberries and wholegrain products may improve endothelial dysfunction and inflammation in overweight and obese individuals at high risk of developing diabetes.	21870174
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Osteoarthritis (OA) is characterized by cartilage attrition, subchondral bone remodeling, osteophyte formation and synovial inflammation.	21870330
Degenerative polyarthritis, Inflammation, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	Perturbed homeostasis caused by inflammation, oxidative stress, mitochondrial dysfunction and proapoptotic/antiapoptotic dysregulation is known to impair chondrocyte survival in joint microenvironments and contribute to OA pathogenesis.	21870330
Urine microscopy leukocytes present finding, Urolithiasis, Urethritis	Altered Intercellular Communication	As shown by reduction of leukocyturia and crystalluria, increased 24-h diuresis in patients with urolithiasis after exposure to ECSWL, a positive effect was achieved on urethral inflammation.	21870476
Communicable Diseases, Pericardial Effusion, CTCAE, Inflammation, Hypothyroidism	Altered Intercellular Communication	Pericardial effusion with pretamponade is an exceptional complication of prolonged hypothyroidism that should be considered in patients presenting with large longstanding but well tolerated pericardial effusion with no evidence of infection or inflammation.	21870563
Inflammation, Alveolar Bone Loss	Altered Intercellular Communication	In both natural teeth and dental implant groups, despite higher MBL measures, cathepsin-K activity, and GCF/PISF volumes with the presence of inflammation, it was the presence of alveolar bone loss that lead to significantly higher values for these parameters.	21870974
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	After 2 years, owing to inflammation and fibrosis, a T-tube was inserted from the glottis to the tracheal bifurcation.	21871319
Inflammation, Brain Injuries	Altered Intercellular Communication	Therefore, common, functionally relevant genetic variants in the key components of this pathway have been associated with greater inflammation post-ictus, further cerebral damage, and ultimately, a worse outcome.	21871809
vascular inflammations, Coronary Arteriosclerosis	Altered Intercellular Communication	We aimed to determine if an abnormal ankle-brachial index (ABI) value as a surrogate of atherosclerotic disease and vascular inflammation provides information on 1-year risk of cardiovascular events after DES implantation.	21872197
Inflammation, Observation Method - Coagulation, Venous Thromboembolism	Altered Intercellular Communication	Since inflammation and coagulation are tightly coupled, we postulated that RBC transfusion may be associated with the development of venous thromboembolic phenomena.	21872295
Communicable Diseases, Inflammation	Altered Intercellular Communication	Hemostasis and inflammation are two tightly interrelated systems in the host's response to infection.	21872299
Sepsis, Inflammation	Altered Intercellular Communication	Thrombin generation in sepsis plays a crucial role in enhancing and modulation of inflammation.	21872299
Inflammation, Malignant Neoplasms, Tuberculosis	Altered Intercellular Communication	Among the 44 patients with sufficient biopsy specimens, 17 patients had malignancy, 12 had tuberculosis, and 15 had nonspecific inflammation.	21873256
Inflammation, Malignant Neoplasms, Tuberculosis	Altered Intercellular Communication	The diagnostic accuracy of US-guided percutaneous biopsy of reticular infiltrations in the mesentery and omentum was 84%; the sensitivity and specificity was, respectively, 89% and 100% for malignancy, 75% and 100% for tuberculosis, and 90% and 83% for nonspecific inflammation.	21873256
Inflammation	Altered Intercellular Communication	Of the 198 joints examined, signs of inflammation were detected by MRI in 49 (24.7%) and by scintigraphy in 48 (24.2%) joints, with agreement between the two methods in 44 joints.	21873267
Inflammation	Altered Intercellular Communication	In another four joints, scintigraphy was positive and MRI negative for signs of inflammation.	21873267
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Effect of serum 25-hydroxyvitamin D on risk for type 2 diabetes may be partially mediated by subclinical inflammation: results from the MONICA/KORA Augsburg study.	21873558
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	To assess the association between serum 25-hydroxyvitamin D (25-OHD) and incident type 2 diabetes and to determine whether the association is mediated by subclinical inflammation.	21873558
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Vitamin D status is inversely related to type 2 diabetes risk and our data suggest that this association may be partially mediated by subclinical inflammation.	21873558
Inflammation, GDC Disease Response Terminology	Altered Intercellular Communication	This result indicates that systemic subclinical inflammation is related with DR, and neutrophil-mediated inflammation may play an important role in the pathogenesis of DR.	21873679
Inflammation, Ischemic stroke	Altered Intercellular Communication	Association of clinical and aetiologic subtype of acute ischaemic stroke with inflammation, oxidative stress and vascular function: a cross-sectional observational study.	21873941
Inflammation, physiopathological, Cerebrovascular accident	Altered Intercellular Communication	The role of inflammation, vascular dysfunction and oxidative stress in the pathophysiology of different stroke subtypes is not well understood.	21873941
Inflammation, Ischemic stroke	Altered Intercellular Communication	We aimed to determine if the clinical and aetiologic subtype of acute ischaemic stroke influences systemic markers of vascular function, inflammation and oxidative stress.	21873941
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Stroke severity (NIHSS score and S100B concentration); systemic markers of inflammation (high sensitivity C-reactive protein [hs-CRP] and fibrinogen), endothelial activation (E-selectin), endothelial cell damage (von Willebrand factor activity), and oxidative stress (F2-isoprostanes) were measured.	21873941
Inflammation, Ischemic stroke, Cerebrovascular accident	Altered Intercellular Communication	These data suggest that stroke aetiology and clinical syndrome may not be important independent determinants of the degree of systemic inflammation, oxidative stress or endothelial function in acute ischaemic stroke.	21873941
Inflammation, Ischemic stroke, Cerebrovascular accident	Altered Intercellular Communication	Other factors, including stroke severity, pre-morbid inflammation and co-morbidity may explain variations among groups of participants with different subtypes of acute ischaemic stroke.	21873941
Inflammation, Lichenoid, Necrosis, Pseudomembrane, Ulcer, Erythema	Altered Intercellular Communication	Clinical and histopathological features were similar in both acute and chronic oral GVHD and included mucosal lichenoid changes, erythema, ulcerations and pseudomembranes, satellite necrosis, apoptotic bodies and lichenoid interface inflammation.	21873943
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The increase of PON1 activity in patients' serum in relation to the control groups indicates a probable pathogenic role of the increased formation of reactive oxygen species in the course of OA and may suggest acute inflammation of the synovial joint.	21873946
Xanthogranulomatous inflammation	Altered Intercellular Communication	These microscopic findings were consistent with xanthogranulomatous inflammation, and the lesion was diagnosed as XGP.	21874438
Inflammation, Obesity	Altered Intercellular Communication	Maternal obesity associated with inflammation in their children.	21874618
Inflammation, Glomerulonephritis, Kidney Diseases	Altered Intercellular Communication	Acute glomerulonephritis (AGN) is a type of renal disease which indicates the inflammation of glomerulus and nephrons.	21874641
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Biopsy of the lung infiltrate by transthoracic computed tomography guided histology needle, showed granulomatous inflammation with necrosis.	21874738
Inflammation	Altered Intercellular Communication	Proposed biological pathways imply that particle-induced pulmonary and systemic inflammation play a role in activating the vascular endothelium and altering vascular function.	21874957
Inflammation, Diabetic Angiopathies, Obesity	Altered Intercellular Communication	According to the concept of adipose tissue expandability, the vascular complications of obesity are related less to the amount of stored fat than to the low-grade inflammation that excess fat storage may elicit.	21875718
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	These findings imply that public health strategies aimed at early prevention of cardiovascular disease may need to target low-grade inflammation rather than only BMI or adiposity.	21875718
Communicable Diseases, Mildly reduced visual acuity, Inflammation	Altered Intercellular Communication	There were no cases of infection, significant inflammation, epithelial problems and reduction in visual acuity.	21876589
Alveolar damage	Altered Intercellular Communication	The most prevalent pulmonary histopathological pattern was diffuse alveolar damage, which was associated with different inflammatory conditions.	21876973
Granulomatous inflammation, Chronic Active Colitis, Tethered Cord Syndrome	Altered Intercellular Communication	On histologic examination, all patients with the cord colitis syndrome had chronic active colitis, with granulomatous inflammation present in 7 of 11 patients (64%).	21879899
ARCN1 gene, Inflammation, Malnutrition	Altered Intercellular Communication	Although smoking is an important trigger of COPD, other factors such as chronic inflammation and malnutrition are known to influence its development.	21880073
Celiac Disease, Inflammation, Malnutrition, ARCN1 gene	Altered Intercellular Communication	Because coeliac disease (CD) is characterized both by dysregulated inflammation and malnutrition, the possibility of an association between CD and COPD was investigated.	21880073
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	Our 3-month study in nondiabetic hypertensive patients showed a decrease in biomarkers of IR and chronic systemic inflammation with the PIO monotherapy and the PIRA combination only, which may help to explain some findings in other cardiovascular outcome trials.	21880242
HD Term Type, Inflammation, Endotoxemia	Altered Intercellular Communication	Subclinical endotoxemia could contribute to increased inflammation and mortality in hemodialysis (HD) patients.	21880509
Inflammation, Neoplasms	Altered Intercellular Communication	Inflammation may result in oxidative stress and contribute to promotion and progression of tumors, including BCC.	21880580
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Pleiotrophin triggers inflammation and increased peritoneal permeability leading to peritoneal fibrosis.	21881556
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Thus, an upregulation of pleiotrophin appears to play a role in fibrosis and inflammation during peritoneal injury.	21881556
allergic inflammation, Immunity, Innate, Influenza	Altered Intercellular Communication	Remarkably, HDM hyporesponsiveness was overcome when exposure occurred concurrently with an acute influenza infection; young mice now displayed robust allergen-specific immunity, allergic inflammation, and lung remodeling.	21881572
Have Autoimmune or Inflammatory Condition, Primary malignant neoplasm	Altered Intercellular Communication	Inhibitory substrates of the proteasomes represent promising approaches to control autoimmune inflammations and induction of apoptosis in cancer cells.	21881828
Inflammation, Ischemia	Altered Intercellular Communication	Misfolding of Notch3 is linked to endoplasmic reticulum stress and increased reactive oxygen species, which may result in dysfunction of endothelial cells, inflammation and ischemia.	21881852
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	RA patients with multiple-joint inflammation may be less physically active than osteoarthritis patients, resulting in a lower demand on the prosthesis, and these patients may, indeed, be good candidates for all-polyethylene tibial TKA.	21881885
Inflammation, Mesentery	Altered Intercellular Communication	Our aim was to report the multidetector-row computed tomography (MDCT) findings of sclerosing mesenteritis, which is a rare disease characterized by chronic nonspecific inflammation of mesenteric adipose tissue.	21882092
Eye pain, Blurred vision, Vitreous opacities, Inflammation	Altered Intercellular Communication	Within two days after injection, blurred vision without ocular pain, anterior chamber inflammation, and vitreous opacity were developed in 6 of the eyes of 6 patients.	21882588
Inflammation	Altered Intercellular Communication	The composite summary score of inflammation was strongly associated with mortality, with the highest risk estimated for individuals with all three inflammatory markers above the median.	21883115
Inflammation	Altered Intercellular Communication	In this study, we aimed to histologically characterize FPLD2-associated lipomatosis and study the expression of genes and proteins involved in cell cycle control, mitochondrial function, inflammation and adipogenesis.	21883346
Trachoma , Inflammation	Altered Intercellular Communication	The overall prevalence of active trachoma (trachomatous inflammation follicular and or trachomatous inflammation intense) was 59% in 1975 and in 2007 was significantly lower at 23% (P<0.001).	21883776
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Increased inflammation as measured by CRP was not consistently detected despite the identification of an ACS precipitant.	21883780
Communicable Diseases, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Infection, inflammatory conditions, moderate-heavy exercise and potentially fast food consumption appear to precipitate high-risk ACS.	21883780
Adenocarcinoma of prostate, Prostatic Intraepithelial Neoplasias, Acute and chronic inflammation	Altered Intercellular Communication	In total, 27 of 40 (68%) patients were found to have adenocarcinoma of the prostate, two patients (5.0%) had atypical small acinar proliferation, one had high-grade prostatic intraepithelial neoplasia (2.5%), four (10%) had chronic active inflammation and six (15%) had benign histology.	21883818
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Systemic inflammation is a major factor influencing the outcome and quality of patient with chronic obstructive pulmonary disease (COPD) and acute exacerbations (AECOPD).	21883889
Tumor necrosis, Inflammation, Septic Shock	Altered Intercellular Communication	We have previously reported elevated levels of angiopoietin-2 in patients with septic shock, and have investigated tumor necrosis factor (TNF)-related and weak inducer of apoptosis (TWEAK), which mediates both angiogenesis and inflammation, in those patients.	21884467
Inflammation, Fibrosis Assessment, Myxoid degeneration, osteoclast activating factor	Altered Intercellular Communication	The level of high-sensitivity C-reactive protein, fibrosis, inflammation, myxoid degeneration, and ubiquitin-aggregates in the atria did not differ between patients with and without POAF.	21885071
Inflammation, Edema	Altered Intercellular Communication	Instead, the two deeper layers decreased in proliferation rate, maintained vessels density unchanged, were cleared of chronic inflammation and oedema and underwent progression towards stable tissue.	21885358
Inflammation	Altered Intercellular Communication	Indeed, while most research has focused on induction of superficial granulation tissue by NPT, deeper layers appear to be also affected, with relieving of chronic inflammation and tissue stabilisation.	21885358
Inflammation	Altered Intercellular Communication	This neutrophilic inflammation of the dermis has been well described in relation to other inflammatory illnesses (i.e.	21885476
Synovitis, Edema of bone marrow, Erosion of bone, Orchitis, Tenosynovitis	Altered Intercellular Communication	MR images were scored according to PsAMRIS (for synovitis, tenosynovitis, periarticular inflammation, bone marrow edema, bone erosion, and bone proliferation) under standardized conditions, in unknown chronological order.	21885513
Synovitis, Orchitis, Edema, Tenosynovitis	Altered Intercellular Communication	The interobserver reliability of PsAMRIS was high for synovitis, tenosynovitis, periarticular inflammation, and bone edema status and change scores (interobserver ICC 0.87-0.97).	21885513
Superficial ulcer, Synovitis, Edema of bone marrow, Orchitis, Tenosynovitis	Altered Intercellular Communication	PsAMRIS sensitivity to change was moderate for synovitis, tenosynovitis, and periarticular inflammation (SRM 0.5-0.8), while poor (SRM 0.1-0.3) for bone marrow edema, erosion, and bone proliferation.	21885513
PROS1 gene, Inflammation	Altered Intercellular Communication	Measures of inflammation were sensitive to change, implying that PsAMRIS may be a valuable tool for monitoring change in inflammation during PsA clinical trials.	21885513
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Telomere dysfunction causes sustained inflammation in chronic obstructive pulmonary disease.	21885626
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is associated with chronic inflammation of unknown pathogenesis.	21885626
ARCN1 gene, Inflammation	Altered Intercellular Communication	To investigate whether telomere dysfunction and senescence of pulmonary vascular endothelial cells (P-ECs) induce inflammation in COPD.	21885626
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	Telomere dysfunction and premature P-EC senescence are major processes perpetuating lung inflammation in COPD.	21885626
Acute abdominal pain, Diverticulum	Altered Intercellular Communication	Inflammation of solitary caecal diverticula:a rare aetiology of acute abdominal pain [corrected].	21887576
Gastrointestinal inflammation	Altered Intercellular Communication	Enterotoxin-producing staphylococci cause intestinal inflammation by a combination of direct epithelial cytopathy and superantigen-mediated T-cell activation.	21887731
Epithelial Damage, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Intestinal biopsies from the patients showed marked epithelial damage with mucosal inflammation.	21887731
Inflammation	Altered Intercellular Communication	Finally, after treatment, a residual inflammation still persisted that might contribute to the observed erythroid disturbances.	21888450
Inflammation	Altered Intercellular Communication	Microscopic examination of the specimen revealed submucosal and deeply seated intra-muscular and mural heterotopic pancreatic tissue, comprised of both ductal and acinar structures, surrounded by exuberant acute and chronic inflammation.	21888463
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Air pollution may promote type 2 diabetes by increasing adipose inflammation and insulin resistance.	21888674
Inflammation, Atherosclerosis	Altered Intercellular Communication	Previously, MBTPS1 and PCSK9 have been shown to regulate cholesterol metabolism and LDL receptor recycling, whereas FURIN and PCSK5 have been suggested to inactivate lipases and regulate inflammation in atherosclerosis.	21889147
Inflammation, Prostatic Diseases	Altered Intercellular Communication	The sensibility of both NF-kB and PSA to inflammation allowed confirming the relationship between these two molecules and its involvement in prostatic diseases progression (inflammatory and neoplasic).	21889270
Inflammation	Altered Intercellular Communication	Inflammation may play a role in mediating these associations.	21889359
Inflammation	Altered Intercellular Communication	Increases in inflammation between 2000 and 2006 were associated with long but not short sleep duration in 2006 for several markers.	21889359
Hyperintensity of cerebral white matter on MRI	Altered Intercellular Communication	Volume of white matter hyperintensities in healthy adults: contribution of age, vascular risk factors, and inflammation-related genetic variants.	21889590
Inflammation, White matter	Altered Intercellular Communication	Vascular risk and inflammation, which increase with age, may contribute to white matter deterioration and proliferation of WMH.	21889590
Inflammation	Altered Intercellular Communication	We investigated whether circulating biomarkers and genetic variants associated with elevated vascular risk and inflammation are associated with WMH volume in healthy adults (144 volunteers, 44-77 years of age).	21889590
nervous system disorder, Inflammation, Congenital Abnormality	Altered Intercellular Communication	Thus, in healthy adults, who are free of neurological and vascular disease, genetic variants that promote inflammation and elevated levels of vascular risk biomarkers can contribute to brain abnormalities.	21889590
Refractory anemias, Inflammation	Altered Intercellular Communication	IL-6 is a key mediator of inflammation in RA.	21889771
ARCN1 gene, Inflammation	Altered Intercellular Communication	Dietary intake of polyunsaturated fatty acids, including omega-3 and omega-6, could modulate chronic obstructive pulmonary disease (COPD) persistent inflammation.	21889886
Inflammation	Altered Intercellular Communication	Ultraviolet (UV) radiation induced inflammation plays an important role in the aging of human skin.	21889965
Inflammation, Reperfusion Injury	Altered Intercellular Communication	Oxidative stress due to ischemia/reperfusion injury increases systemic inflammation and impairs immune defenses.	21890323
Inflammation	Altered Intercellular Communication	Our data emphasize the high burden of disease, the persistence of inflammation and the existence of clinical possible phenotypes population sharing common features with published cohorts.	21890336
Barrett Esophagus, Primary malignant neoplasm	Altered Intercellular Communication	The findings of the present study provide evidence of ectopic AID expression in Barrett's oesophagus and Barrett's oesophageal adenocarcinoma, a cancer that develops under chronic inflammatory conditions.	21890457
Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Congestive heart failure, Chronic heart failure	Altered Intercellular Communication	Low-grade inflammation has been associated with cardiovascular disease (CVD) and chronic heart failure (CHF).	21890535
Inflammation, Interstitial inflammation, Fibrosis Assessment, Interstitial Fibrosis Assessment, Hypertension, CTCAE	Altered Intercellular Communication	Hypertension at presentation, fibrointimal proliferation of arterial vessels, interstitial fibrosis and interstitial inflammation were shown to be associated with >=50% increase of plasma creatinine level from baseline in univariate analysis (P<0.05 for hypertension and fibrointimal proliferation; P<0.01 for interstitial fibrosis and inflammation).	21891776
Communicable Diseases, Inflammation, Herpes, Neuronal loss in central nervous system	Altered Intercellular Communication	In fact, Nectin-2 (NC-2); apolipoprotein E (APOE); glycoprotein carcinoembryonic antigen related cell adhesion molecule-16 (CEACAM-16); B-cell lymphoma-3 (Bcl-3); translocase of outer mitochondrial membrane 40 homolog (T0MM-40); complement receptor-1 (CR-l); APOJ or clusterin and C-type lectin domain A family-16 member (CLEC-16A); Phosphatidyl inositol- binding clathrin assembly protein gene (PICALM); ATP-bonding cassette, sub family A, member 7 (ABCA7); membrane spanning A4 (MSA4); CD2 associated protein (CD2AP); cluster of differentiation 33 (CD33); and ephrin receptor A1 (EPHA1) result in a genetic signature that might affect individual brain susceptibility to infection by the herpes virus family during aging, leading to neuronal loss, inflammation, and amyloid deposition.	21891868
Tumor necrosis, Nerve Degeneration	Altered Intercellular Communication	It presents the evidence that dyotic endocrine signals modulate the expression of tumor necrosis factor (TNF) and related cytokines, and that these cytokines are a functionally important downstream link mediating neurodegeneration and dysfunction.	21891866
Granulomatous inflammation, Skin lesion	Altered Intercellular Communication	A biopsy specimen from the skin lesion revealed granulomatous inflammation with hyphae.	21891986
Pneumonitis	Altered Intercellular Communication	High mobility group box-1 (HMGB-1) is an important pro-inflammatory mediator that contributes to acute lung inflammation.	21893977
Communicable Diseases, Inflammation, Malignant Neoplasms, Disturbance	Altered Intercellular Communication	C-reactive protein (CRP), serum amyloid A (SAA), interleukin-6 (IL-6), a1-antitrypsin (a1AT), a1-acid glycoprotein (a1AG) and ceruloplasmin (CP) are acute inflammatory biomarkers that increase in various conditions including infection, inflammation, malignancy and tissue disturbance.	21894431
Inflammation	Altered Intercellular Communication	To compare joint inflammation assessment using subjective grading of power Doppler ultrasonography (PDUS) and contrast-enhanced ultrasonography (CEUS) versus computer-aided objective CEUS quantification.	21894599
Sleep-Disordered Breathing, Inflammation	Altered Intercellular Communication	Relationship between sleep-disordered breathing and markers of systemic inflammation in women from the general population.	21895822
Sleep-Disordered Breathing, Inflammation, Obesity	Altered Intercellular Communication	Also, for women from the general population there is an independent correlation between SDB and inflammation, even after adjusting for obesity.	21895822
Inflammation, Sleep Apnea, Obstructive, Hypoxia	Altered Intercellular Communication	The results indicate that intermittent hypoxia, and not the AHI, is related to systemic inflammation seen in OSAS.	21895822
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Inflammation, both local and systemic, is a hallmark of chronic obstructive pulmonary disease (COPD).	21896197
ARCN1 gene	Altered Intercellular Communication	Our results indicate that systemic neutrophil responses in COPD patients are caused by a unique but subtle interplay between multiple inflammatory signals.	21896197
Inflammation, Cortical Dysplasia, Fleck corneal dystrophy	Altered Intercellular Communication	She underwent a right hemispherotomy, and histological examination showed signs of inflammation and features of focal cortical dysplasia (FCD).	21896424
Hepatitis C	Altered Intercellular Communication	Association of hepatitis C virus infection and malnutrition-inflammation complex syndrome in maintenance hemodialysis patients.	21896499
Communicable Diseases, Hepatitis C	Altered Intercellular Communication	Patients undergoing maintenance hemodialysis (MHD) have a significantly higher prevalence of hepatitis C virus (HCV) infection and malnutrition-inflammation complex syndrome (MICS).	21896499
Conjunctival scar, Corneal Opacity, Conjunctivitis	Altered Intercellular Communication	Entropion was more severe among those with a low BMI, those who were female, those aged less than 50 years, and those with moderate to severe conjunctival inflammation, central corneal opacity, and severe conjunctival scarring.	21896855
Inflammation, Blood Clot, Aortic Aneurysm, Abdominal, Glucocorticoid deficiency with achalasia, Atherosclerotic lesion	Altered Intercellular Communication	Abdominal aortic aneurysms (AAAs) are characterized by presence of high proteolytic activity, atherosclerotic lesions, extensive transmural inflammation and the presence of variably sized and shaped intraluminal thrombus (ILT).	21897000
APP gene, Inflammation, Blood Clot	Altered Intercellular Communication	Association of higher plasma levels of MMP-9 and CRP with thin ILT may be related to two phenomena: thin thrombi convey more elastolysis-stimulating factors from blood to the AAA wall and thin thrombi convey more factors involved in proteolysis and inflammation from AAA wall to blood.	21897000
Inflammation	Altered Intercellular Communication	There was no difference in plasma citrulline concentrations among those with confirmed inflammation by imaging or endoscopy (confirmed, 26.2+-11.8; negative, 28.0+-10.0; independent t test P=0.583).	21897281
hearing impairment, Inflammation, Atrophic, Communicable Diseases	Altered Intercellular Communication	This first reported otopathologic case of SS with hearing loss showed atrophy and degeneration involving the apical halves of the cochlear duct without inflammation or infection.	21897318
Inflammation	Altered Intercellular Communication	A newly identified cytokine, IL-33, appears to be an important pro-inflammatory cytokine promoting tissue inflammation.	21898270
ARCN1 gene, Inflammation, Psychiatric, Neurocirculatory Asthenia	Altered Intercellular Communication	There is growing awareness of systemic inflammation and cardiovascular, neurologic, psychiatric, and endocrine comorbidities associated with COPD.	21898277
Epiglottitis, Inflammation	Altered Intercellular Communication	Acute supraglottitis in adults seems to be a different entity than epiglottitis in children, and inflammation does not usually exclusively involve the epiglottis.	21898436
Inflammation	Altered Intercellular Communication	Chitinases and chitinase-like proteins play a role in Th2-type inflammation.	21899483
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by local inflammation of the upper airways and sinuses and is frequently divided into polypoid CRS (CRSwNP) and nonpolypoid CRS (CRSsNP).	21899560
Inflammation, Craniosynostosis	Altered Intercellular Communication	However, the mechanism of inflammation in CRS has still not been fully elucidated.	21899560
Inflammation, Craniosynostosis	Altered Intercellular Communication	Overproduction of IL-32 may be involved in the pathogenesis of CRS, although the role of IL-32 in the inflammation in CRSsNP and CRSwNP may be different.	21899560
Necrotizing granulomatous inflammation, Aggregation	Altered Intercellular Communication	Biopsy of the mass showed sarcoidal type granulomatous inflammation with nodular aggregations of non-necrotizing epithelioid histiocytes in the subcutis.	21899592
Tumor necrosis, Rheumatoid Arthritis, Psoriasis	Altered Intercellular Communication	Biologic response modifiers targeting tumor necrosis factor alpha (TNFa) are effective treatments of chronic inflammatory conditions such as rheumatoid arthritis and psoriasis.	21899592
Inflammation	Altered Intercellular Communication	While exercise acts to combat inflammation and aging, the ability to exercise may itself be compromised by inflammation and inflammation's impact on muscle recovery and joint inflammation.	21899733
Inflammation	Altered Intercellular Communication	While exercise acts to combat inflammation and aging, the ability to exercise may itself be compromised by inflammation and inflammation's impact on muscle recovery and joint inflammation.	21899733
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	In this discovery phase, significant differences were found for 21 serum proteins implicated in inflammation, oxidation, metabolic regulation, and autoimmunity.	21900154
Inflammation, Renal Cell Carcinoma	Altered Intercellular Communication	Collectively, our results show that TAMs, often present in RCCs, display enhanced 15-LOX2 activity that contributes to RCC-related inflammation, immunosuppression, and malignant progression.	21900394
Refractory Cytopenia of Childhood, Inflammation, Neoplasms	Altered Intercellular Communication	We propose that manipulating LOX-dependent arachidonic acid metabolism in the tumor microenvironment could offer new strategies to block cancer-related inflammation and immune escape in patients with RCC.	21900394
Uveitis	Altered Intercellular Communication	Clinical and imaging characteristics for the four patients include absence of intraocular inflammation, late staining of lesions on fluorescein angiography, and hypofluorescence of lesions on indocyanine green.	21900853
Inflammation, Obesity	Altered Intercellular Communication	Inflammation associated with obesity: relationship with blood and bone marrow endothelial cells.	21901025
Inflammation, Thrombosis, Stasis, Heart Failure, Systolic	Altered Intercellular Communication	Thrombosis within the vascular system in relation with inflammation and stasis might be associated with poor prognosis in patients with systolic heart failure (HF).	21901368
Barrett Esophagus, Inflammation, Esophageal injury	Altered Intercellular Communication	The etiology of this complex disease has been attributed to a variety of factors, including an excess of iron (resulting in increased tumourigenesis), oesophageal injury and inflammation (due in part to Barrett's oesophagus and smoking among others).	21901748
Gastrointestinal inflammation	Altered Intercellular Communication	Intestinal commensal flora seems to be a requisite for both human and experimental intestinal inflammation.	21902690
Inflammation	Altered Intercellular Communication	The pathogenesis of BP is controversial and is believed to be caused by inflammation of the facial nerve at the geniculate ganglion.	21903566
Inflammation, Corneal edema	Altered Intercellular Communication	Examination showed corneal edema, inflammation, and secondary angle closure.	21904171
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Interleukin (IL)-17 producing cells play key roles in chronic inflammation and autoimmunity.	21904631
Adenocarcinoma of prostate, prostatitis	Altered Intercellular Communication	Little is known about the relevance of IL-17 producing cells at sites of prostate tissue inflammation and/or prostate adenocarcinoma.	21904631
Inflammation, Musculoskeletal torsion, function	Altered Intercellular Communication	These findings suggested auto-amputation of the ovary either by inflammation or torsion.	21904862
Refractory anemias, Tumor necrosis, Inflammation, Vascular System Injuries	Altered Intercellular Communication	Tumor necrosis factor a (TNFa) is the major mediator of inflammation in RA, related to vascular injury by targeting VE-cadherin, an endothelium-specific adhesion molecule of vital importance for endothelium integrity and angiogenesis.	21905018
Inflammation	Altered Intercellular Communication	If mBMD loss is driven by inflammation, we expect to find mBMD gain in patients who are in remission.	21905248
Inflammation	Altered Intercellular Communication	This suggests that mBMD loss is driven by inflammation.	21905248
Degenerative polyarthritis, Osteoarthritis, Knee, Myositis	Altered Intercellular Communication	Patients with knee osteoarthritis (OA) are characterized by increased muscle inflammation and altered gait.	21905256
Myositis	Altered Intercellular Communication	Identification of the cellular and molecular mechanisms associated with muscle inflammation is important to better understand the underlying mechanism responsible for altered gait and function in patients with knee OA.	21905256
Sepsis, Inflammation	Altered Intercellular Communication	C-reactive protein (CRP) is synthesized in the liver in response to inflammation, and CRP is a widely used marker of sepsis.	21905978
Tendinitis, Arthritis, Enthesopathy	Altered Intercellular Communication	Poor correlation was found between conventional clinical examination and US in cases with joint inflammation, tendonitis and, more particularly, those cases with enthesopathy.	21906427
palladium, Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	Our findings suggest that elevated plasma EN-RAGE and decreased sRAGE level could play a crucial role in systemic inflammation and carotid atherosclerosis in PD patients.	21906738
Inflammation, Chronic Kidney Diseases, Obesity	Altered Intercellular Communication	Systemic inflammation is a hallmark of chronic kidney disease (CKD) and obesity represents a major risk factor for CKD.	21906921
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Increased lipid peroxidation and inflammation are major factors in the pathogenesis of nonalcoholic fatty liver disease (NAFLD).	21907687
Hepatic inflammation, Myeloid Leukemia, Chronic	Altered Intercellular Communication	A lipoxidation product that could play a role in the induction of hepatic inflammation is N(e)-(carboxymethyl)lysine (CML).	21907687
Steatohepatitis, Myeloid Leukemia, Chronic, Hepatic inflammation	Altered Intercellular Communication	CML accumulation was significantly associated with the grade of hepatic steatosis, the grade of hepatic inflammation, and gene expression levels of inflammatory markers PAI-1, IL-8, and CRP.	21907687
Inflammation, Carcinoma of lung, Breast Carcinoma	Altered Intercellular Communication	We compared plasma protein profiles of four mouse models of lung cancer with profiles of models of pancreatic, ovarian, colon, prostate, and breast cancer and two models of inflammation.	21907921
Inflammation, Hyperparathyroidism	Altered Intercellular Communication	Impact of cholecalciferol treatment on biomarkers of inflammation and myocardial structure in hemodialysis patients without hyperparathyroidism.	21908203
Inflammation, Cardiac dysfunction, Electrocardiogram: left ventricle hypertrophy (finding)	Altered Intercellular Communication	Additionally, we observed a reduction in important surrogate markers of cardiovascular risk, namely systemic inflammation and left ventricular hypertrophy, suggesting an anti-inflammatory action and possibly an improvement of cardiac dysfunction.	21908203
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Effects of alpha-lipoic acid supplementation on inflammation, oxidative stress, and serum lipid profile levels in patients with end-stage renal disease on hemodialysis.	21908204
Fever, CTCAE, Neoplasms, Meningitis, Intervertebral Disk Displacement, Musculoskeletal Pain, Cervical spondylosis, Spinal Diseases	Altered Intercellular Communication	Patients were initially diagnosed with meningitis (n=4), fever of unknown origin (n=2), cervical spondylosis (n=2), polymyalgia rheumatica (n=1), upper respiratory tract inflammation (n=1), metastatic spinal tumor (n=1), cervical spondylotic myelopathy (n=1), and cervical disc herniation (n=1).	21909038
Inflammation, Mitochondria	Altered Intercellular Communication	The primary triggers for motor neuron degeneration are unknown but inflammation, oxidative stress and mitochondrial defects have been identified as potential contributing factors.	21909419
Neoplasm Metastasis, Gastrointestinal inflammation, Neoplasms	Altered Intercellular Communication	SMAD7 regulates gastrointestinal inflammation by inhibiting transforming growth factor-b (TGFB), which can act as both a tumor suppressor and a promoter of metastasis.	21910156
Inflammation, Temporomandibular Joint, Neoplasms, Traumatic injury, Hernia	Altered Intercellular Communication	Neoplasm, trauma or inflammation in this area can result in displacement of the temporomandibular joint into the ear canal; however, spontaneous herniation is rare.	21910955
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Asthma and chronic obstructive pulmonary disease (COPD) display features of overlap in airway physiology and airway inflammation.	21912093
Airway structure, ARCN1 gene, Asthma	Altered Intercellular Communication	To explore the relationship of airway inflammation and cytokine and chemokine expression in asthma and COPD.	21912093
Airway structure, neutrophilic	Altered Intercellular Communication	In neutrophilic and eosinophilic airway inflammation, TNFa, TNFRI, TNFRII, IL-6, IL-8 and IL-5 could differentiate between these phenotypes.	21912093
Inflammation, F8 wt Allele	Altered Intercellular Communication	Circulating markers of inflammation may be useful in gauging prognosis in patients with AHF.	21912122
vascular inflammations, Endothelial dysfunction	Altered Intercellular Communication	In addition to its cholesterol-lowering effect, the ability of simvastatin to ameliorate endothelial dysfunction through increasing NO bioavailability and through suppression of oxidative stress and vascular inflammation and its ability to enhance the effect of ramipril on these parameters may play a pivotal role in these effects.	21913974
Inflammation, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	Increasing evidence correlates the presence of systemic inflammation with poor survival in patients with hepatocellular carcinoma (HCC).	21913982
Inflammation, Steroid-sensitive nephrotic syndrome, Cerebral dysfunction	Altered Intercellular Communication	Cerebral amyloid angiopathy-related inflammation presenting with steroid-responsive higher brain dysfunction: case report and review of the literature.	21914214
Cerebral Amyloid Angiopathy, Inflammation	Altered Intercellular Communication	Histological pathology disclosed b-amyloid in the blood vessels and perivascular inflammation, which highlights the diagnosis of cerebral amyloid angiopathy (CAA)-related inflammation.	21914214
Cerebral dysfunction	Altered Intercellular Communication	Here we report a patient with CAA-related inflammation who showed higher brain dysfunction that improved with steroid therapy.	21914214
Crohn Disease, Granulomatous inflammation	Altered Intercellular Communication	Renal involvement in Crohn's disease: granulomatous inflammation in the form of mass lesion.	21915060
Renal mass	Altered Intercellular Communication	From now on, differential diagnostics of renal mass lesions in CD should include the tumor-like, Crohn's-type granulomatous inflammation as direct kidney manifestation of the disease.	21915060
Inflammation, Multiple Chronic Conditions	Altered Intercellular Communication	Several studies have linked dietary patterns to insulin sensitivity and systemic inflammation, which affect risk of multiple chronic diseases.	21915138
Inflammation	Altered Intercellular Communication	A dietary pattern high in low-fat dairy products, fruit, whole grains, poultry, fish and vegetables may be associated with greater insulin sensitivity and lower systemic inflammation in older adults.	21915138
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	Thus our results suggest that chitinase-related genes may play an important role in establishing pulmonary inflammation and emphysematous changes in smokers and COPD patients.	21915293
Inflammation, Muscle damage	Altered Intercellular Communication	Comparison of minimally invasive direct anterior versus posterior total hip arthroplasty based on inflammation and muscle damage markers.	21915544
Muscle damage, Inflammation, Soft Tissue Injuries	Altered Intercellular Communication	We prospectively analyzed biochemical markers of muscle damage and inflammation in patients treated with minimally invasive total hip arthroplasty with an anterior or posterior approach to provide objective evidence of the local soft-tissue injury at the time of arthroplasty.	21915544
Inflammation, Muscle damage	Altered Intercellular Communication	Independent predictors of elevation in levels of markers of inflammation and muscle damage were determined with use of multivariate logistic regression analysis.	21915544
Inflammation	Altered Intercellular Communication	The levels of the markers of inflammation were slightly decreased in the direct-anterior-approach group as compared with those in the posterior-approach group.	21915544
Inflammation, Sleep Apnea, Obstructive, Ischemic stroke	Altered Intercellular Communication	Obstructive sleep apnea and biomarkers of inflammation in ischemic stroke.	21916851
Inflammation, Thyroid associated opthalmopathies	Altered Intercellular Communication	Excessive orbital fibroblast (OF) proliferation and extracellular matrix production, as well as inflammation resulting in the expansion and remodeling of orbital tissue, are characteristic of Graves ophthalmopathy (GO).	21917865
Hypoglycemia	Altered Intercellular Communication	Day 2 hypoglycemia counterregulatory hormonal response and glucose turnover [(3-(3)H)-glucose] as indicators of recovery from hypoglycemia.	21917871
Cessation of life, Inflammation, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	Upregulated pathways included death receptor-mediated caspase cascade, mitochondrial dysfunction, endoplasmic reticulum stress, calpains leading to apoptotic cell death, NF-kB and JAK/STAT pathways, and inflammasome-assembly mediating inflammation.	21917936
Communicable Diseases, Inflammation	Altered Intercellular Communication	Thus, T(reg) might contribute to the chronic infection and systemic spread of T. whipplei in CWD but in contrast prevent mucosal barrier defect by reducing local inflammation.	21918190
Micropenis, Cryptorchidism	Altered Intercellular Communication	Clinically it is characterized by low serum concentrations of testosterone and inadequate low levels of luteinizing hormone and follicle-stimulating hormone as well as incomplete sexual maturation, lack of secondary sexual features (facial and body hair growth, deepening of the voice), micropenis and sometimes even cryptorchidism.	21918848
Sense of smell impaired, Osteoporosis, Cryptorchidism, Infertility, Micropenis, Anemia, Erectile dysfunction	Altered Intercellular Communication	A 19-year-old man presented to our male infertility clinic with delayed sexual maturation, eunuchoid habitus, micropenis, cryptorchidism, erectile dysfunction and absence of ejaculation, anemia and osteoporosis as well as low serum concentrations of luteinizing hormone, follicle-stimulating hormone and testosterone in combination with hyposmia.	21918848
Cerebrovascular Disorders, Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a central role in the pathogenesis of atherosclerosis but no randomized studies have evaluated anti-inflammatory therapy in patients with acute coronary or cerebrovascular disease.	21918905
Inflammation, Acute Coronary Syndrome, Ischemic stroke	Altered Intercellular Communication	In conclusion, our pilot study provided no evidence that colchicine 1 mg daily for 30 days compared with placebo suppresses inflammation in patients with acute coronary syndrome or acute ischemic stroke.	21918905
Sarcopenia	Altered Intercellular Communication	The loss of muscle mass and sarcopenia: non hormonal intervention.	21920428
Inflammation, Edema	Altered Intercellular Communication	The presence of tissue edema was strongly associated with the level of clinical inflammation.	21920608
Inflammation	Altered Intercellular Communication	Chronic local inflammation is considered to underlie painful symptomatology.	21920667
Hyperleucinemia, Inflammation, Hypertension, CTCAE, Overweight	Altered Intercellular Communication	Hyperleptinemia is associated with hypertension, systemic inflammation and insulin resistance in overweight but not in normal weight men.	21920718
Communicable Diseases, Inflammation, glycation	Altered Intercellular Communication	The receptor for advanced glycation end-products (RAGE) is a pattern-recognition receptor involved in the host response to injury, infection and inflammation.	21920897
ARCN1 gene, Inflammation, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	We determined whether airway and systemic levels of sRAGE and the RAGE ligands HMGB1 (high-mobility group box-1) and serum amyloid A (SAA) are related to neutrophilic inflammation in asthma and chronic obstructive pulmonary disease (COPD).	21920897
ARCN1 gene, Asthma	Altered Intercellular Communication	Neutrophilic airway inflammation in asthma and COPD is associated with reduced sRAGE.	21920897
Alzheimers Disease", Ototoxicity, Data types - Address	Altered Intercellular Communication	Glutamate (Glu) is the most abundant excitatory neurotransmitter in the central nervous system (CNS) and is involved in the pathophysiology of Alzheimer's disease (AD) in which there is an increased excitotoxicity.	21921084
Refractory anemias, Inflammation, Arthritis	Altered Intercellular Communication	The high frequency of Foxp3+ T cells in pSpA might contribute to the spontaneous resolution and remitting course of arthritis in pSpA as compared to the more persistent joint inflammation in RA.	21921098
Inflammation, Necrosis, Fracture, Hypertrophy, Hyperplasia	Altered Intercellular Communication	HE staining showed: shrinkage, necrosis, and irregular arrange of the articular chondrocytes, extracellular matrix fracture, hypertrophy and hyperplasia synovium, infiltration of lymphoid and mononuclear cells and proliferation of many small blood vessels in the experimental group; regular arrangement of the articular chondrocytes, the homogeneously staining matrix, and synovial tissue without chronic inflammation and significant proliferation in the normal control group.	21923032
Inflammation, Arthritis, Periarticular calcification	Altered Intercellular Communication	Arthritis is defined by inflammation, cartilage and bone destruction/formation and articular calcifications.	21923476
Inflammation, Arthritis	Altered Intercellular Communication	Our objectives were to evaluate ucMGP levels in synovial fluid (SF) in arthritis patients and to investigate the relationship between local and circulating ucMGP and their association with age and inflammation.	21923476
Inflammation	Altered Intercellular Communication	Transmural histopathological scoring of acute inflammation (AIS) was performed at all locations (score 0-13).	21924572
Crohn Disease, Inflammation	Altered Intercellular Communication	The MRI activity index was applied to 26 Crohn's patients (mean age 32, range 13-69 years, 15 male) and correlated to terminal ileal biopsy scores of acute inflammation ("eAIS" score 1-6).	21924572
Inflammation	Altered Intercellular Communication	The model achieved a sensitivity of 0.81 (95% CI 0.54-0.96), specificity of 0.70 (0.35-0.93) and AUC 0.77 for predicting acute inflammation (eAIS >=2).	21924572
Inflammation, Chronic heart failure	Altered Intercellular Communication	Systemic inflammation and cell activation reflects morbidity in chronic heart failure.	21924921
Inflammation, Heart failure	Altered Intercellular Communication	Immune activation and inflammation play critical roles in the development of heart failure (HF).	21925559
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	To investigate the effects of inflammation on perfusion regulation and brain volumes in type 2 diabetes.	21926285
Symptoms, Inflammation, Arteritis	Altered Intercellular Communication	After the re-introduction of the IFN beta-1a, the patient had a gradual worsening of the arteritis, with claudication symptoms in the left arm and increased inflammation markers.	21928043
Inflammation, Carcinogenesis	Altered Intercellular Communication	The angiotensin I-converting enzyme (ACE) is involved in cell proliferation, angiogenesis, inflammation, and tissue remodeling, all of which could play a role in carcinogenesis.	21928698
Inflammation, Leukemic Infiltration, Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Lymphoplasmacytic Infiltrate	Altered Intercellular Communication	In cases with both CLL/SLL and inflammatory infiltrates, it is unknown whether the CLL infiltrate represents a nonspecific "passenger effect" secondary to ongoing inflammation or pathologic leukemic pulmonary infiltration (LPI).	21929283
Inflammation, Acute inflammation	Altered Intercellular Communication	LPI was found in 2 of 21 cases (9.5%) with acute inflammation, 0 of 10 cases of chronic inflammation and in 7 of 18 cases (38.8%) without any pathologic findings of acute or chronic inflammation (p = 0.01).	21929283
Inflammation, Infiltration, Chronic Lymphocytic Leukemia	Altered Intercellular Communication	These results demonstrate that LPI identified in biopsies with concurrent inflammation is uncommon, and that most inflammatory infiltrates in patients with CLL do not cause "passenger effect" CLL infiltration.	21929283
Amenorrhea	Altered Intercellular Communication	The condition usually first becomes apparent in adolescence with delayed puberty and primary amenorrhea due to the gonads have no hormonal or reproductive potential.	21929773
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Accumulative evidence suggested that oxidative stress and inflammation were involved in the pathogenesis of atrial fibrillation (AF).	21930315
Inflammation	Altered Intercellular Communication	The increased protective capacity of the Tyr(402) Factor H variant allows better and more efficient clearance and removal of cellular debris and reduces inflammation and pathology.	21930971
Hyperglycemia	Altered Intercellular Communication	The present findings indicate that pathways regulating glucose uptake in skeletal muscle may be involved in the development of inflammation-associated hyperglycemia.	21931634
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Patients with type 2 diabetes exhibit changes in these pathways, which may ultimately render such patients more prone to develop dysregulated glucose disposal in the context of systemic inflammation.	21931634
Gingivitis	Altered Intercellular Communication	These cytokines have been reported to correlate with gingival inflammation and periodontal status.	21932007
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Inflammation accompanied by severe oxidative stress plays a vital role in the orchestration and progression of neurodegeneration prevalent in chronic and acute central nervous system pathologies as well as in aging.	21932365
Interstitial Fibrosis Assessment, Interstitial inflammation, Tubular atrophy	Altered Intercellular Communication	Cox proportional hazard analysis showed that the glomerular classes were not significant variables, while interstitial fibrosis, tubular atrophy and interstitial inflammation were independent variables associated with renal end-point (HR: 3.36 (95% confidence interval: 1.21-9.32), 4.74 (1.26-17.91)).	21933307
Inflammation, Cervical Disc Degenerative Disorder	Altered Intercellular Communication	The degeneration of cervical PLL may be related to inflammation.	21933591
Carotid Atherosclerosis	Altered Intercellular Communication	Imaging intraplaque inflammation in carotid atherosclerosis with 11C-PK11195 positron emission tomography/computed tomography.	21933781
Diabetes Mellitus, Non-Insulin-Dependent, Vascular Diseases, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Although perturbations of haemostatic markers have been shown to be associated with macrovascular disease in patients with type 2 diabetes, it is unclear whether these are primarily due to endothelial dysfunction or a result of inflammation.	21934489
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The present study was undertaken to elucidate whether elevated levels of factor VIII (FVIII) and von Willebrand factor (vWF) in women with type 2 diabetes represent endothelial dysfunction, inflammation or an alternate mechanism.	21934489
Inflammation, Endothelium	Altered Intercellular Communication	It also appears that this is not mediated by inflammation or endothelial injury and is likely to be due to an alternate mechanism.	21934489
Keratopathy, Uveitis	Altered Intercellular Communication	All the eyes with band-shaped keratopathy showed recurrent and chronic intraocular inflammation.	21934492
Keratopathy, Uveomeningoencephalitic Syndrome, Intraocular inflammation	Altered Intercellular Communication	Band-shaped keratopathy is a relatively uncommon complication in VKH syndrome and mostly occurs in relatively younger patients with a long course of chronic intraocular inflammation.	21934492
Inflammation, Fever, CTCAE	Altered Intercellular Communication	We report the case of an 82-year-old man with aortic prosthesis inflammation in whom fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography has been useful in the detection of the cause of fever of unknown origin.	21934523
Inflammation, Gout	Altered Intercellular Communication	Gout can lead to inflammation and damage to cartilage, bone, bursa, tendons, heart, or kidneys.	21934587
Inflammation, Hyperuricemia, Gout	Altered Intercellular Communication	Patients with gout will have many years of asymptomatic hyperuricemia followed by episodes of acute gouty inflammation and asymptomatic periods.	21934587
Refractory anemias, Inflammation	Altered Intercellular Communication	Conclusively, IL-33 is involved in the pathogenesis of RA and may reflect the degree of inflammation in patients with RA.	21935266
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Diabetes mellitus is associated with enhanced inflammation within AS valves, measured by CRP expression, which may contribute to faster AS progression.	21935671
Inflammation	Altered Intercellular Communication	Free radicals and redox signalling in T-cells during chronic inflammation and ageing.	21936801
Inflammation	Altered Intercellular Communication	During chronic inflammation and ageing, the increase in oxidative stress in both intracellular and extracellular compartments is likely to influence local cell functions.	21936801
Burning sensation, Neurogenic Inflammation, Hyperalgesia	Altered Intercellular Communication	Lingual burning in patients with glossopyrosis is consistent with hyperalgesia and neurogenic inflammation observed in patients and animals with magnesium deficiency and in magnesium deficient tissues.	21937022
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Chronic inflammation contributes to insulin resistance and type 2 diabetes mellitus (T2DM).	21938543
Cataract, Intraocular inflammation, Uveitis	Altered Intercellular Communication	The results indicate that uveitis is not a formal contraindication to primary IOL implantation in the management of pediatric cataract surgery in cases with full control of intraocular inflammation.	21940141
Intestinal metaplasia, Inflammation, Gland	Altered Intercellular Communication	Using the updated Sydney System, histological parameters including activity, chronic inflammation, glandular atrophy and intestinal metaplasia were graded.	21940353
Hyalinosis, Systemic, Inflammation	Altered Intercellular Communication	Some clinicians think that HFS is a type of inflammation limited to the hands and feet and can be prevented with a COX-2 inhibitor (celecoxib).	21940785
Inflammation, Thrombosis	Altered Intercellular Communication	Thrombosis of the sac is thought to induce perianeurysmal brain inflammation, but such phenomena have never been studied in flow-diverter devices.	21940808
Inflammation, Vasogenic Edema	Altered Intercellular Communication	MR imaging revealed signs highly suggestive of perianeurysmal inflammation with vasogenic edema and blood-brain barrier breakdown.	21940808
ACSM3 gene, Inflammation, Subarachnoid Hemorrhage	Altered Intercellular Communication	Subarachnoid hemorrhage (SAH) pathophysiology involves neurovascular proteolysis and inflammation.	21940962
ACSM3 gene, Inflammation	Altered Intercellular Communication	Because pGSN is known to inhibit inflammatory mediators, these findings suggest that MMPs may reduce pGSN and exacerbate inflammation after SAH.	21940962
Inflammatory abnormality of the eye	Altered Intercellular Communication	These histopathologic findings provide evidence that TB penetrates the ocular surface, induces regression of OSN, and possibly moderates ocular inflammation.	21941176
Inflammation, cervical cancer, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	Of the 409 ASC-US, 42.1% showed inflammation; 50.9% had CIN 1, 6.1% had CIN 2, and three cases had CIN 3, one of which was cervical cancer.	21941964
Airway structure, Asthma	Altered Intercellular Communication	Association of airway inflammation with asthma control level evaluated by the asthma control test.	21942275
Airway structure, Asthma	Altered Intercellular Communication	The association between airway inflammation and asthma control level is not clear at present.	21942275
Airway structure	Altered Intercellular Communication	We also evaluated the association between the scores for each ACT question item and eosinophilic or neutrophilic airway inflammation.	21942275
Inflammation	Altered Intercellular Communication	Asthma control level evaluated by the ACT was not associated with airway eosinophilic or neutrophilic inflammation.	21942275
Inflammation	Altered Intercellular Communication	Considering that inflammation and oxidative stress are involved in HF evolution, we investigated lipoprotein-associated phospholipase A2 (LpPLA2), an enzyme involved in these pathophysiologic processes in relation to EF.	21942556
vascular inflammations	Altered Intercellular Communication	Confirming its role as a marker of vascular inflammation, LpPLA2 seems to be a biomarker constantly correlated with HF, regardless of etiology.	21942556
Inflammation, Periodontal Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Periodontal disease (inflammation of the tissues surrounding teeth) is also widespread, and may contribute to the risk of cardiovascular diseases via pathogenic inflammatory pathways.	21943132
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is associated with systemic inflammation.	21943856
ARCN1 gene, Inflammation, Atherosclerosis	Altered Intercellular Communication	These findings suggest that systemic inflammation may play a potential role in preclinical atherosclerosis in COPD.	21943856
Nasal Polyps, Eosinophilic disorder, Craniosynostosis, Nail-Patella Syndrome, Chronic sinusitis	Altered Intercellular Communication	Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with T(H)2-dominant inflammation, including eosinophilia, which is in contrast to chronic rhinosinusitis (CRS) without nasal polyps (NPs).	21943944
Inflammation	Altered Intercellular Communication	Overproduction of CCL18 might contribute to the pathogenesis of CRSwNP through its known activities, which include recruitment of lymphocytes and dendritic cells, activation of fibroblasts, and initiation of local inflammation.	21943944
Inflammation, Conventional (Clear Cell) Renal Cell Carcinoma	Altered Intercellular Communication	Many signaling pathways are implicated in clear cell renal carcinoma development, including the inflammation pathway.	21944129
Cessation of life, Inflammation, Conventional (Clear Cell) Renal Cell Carcinoma	Altered Intercellular Communication	Results suggest that inflammation gene expression may be significant prognostic biomarkers for the risk of recurrence (GADD45G) and death (CARD9, CIITA and NCF2) in patients with clear cell renal carcinoma.	21944129
Inflammation, Thickened, Blood Clot, Pannus, Tears body substance, Calcinosis	Altered Intercellular Communication	Cusp tears and thickening, calcification (at radiography), pannus formation, inflammation, and thrombus deposition were noted.	21944438
Inflammation	Altered Intercellular Communication	Extensive retroperitoneal inflammation extending into the paravisceral aorta was encountered.	21944481
Inflammation, Leucocytic infiltrate, Fibrosis Assessment, Aneurysm, Ruptured, Vessel perforation, Phlebitis, Infiltration	Altered Intercellular Communication	Histology demonstrated vessel wall rupture, adventitial fibrosis and inflammatory cell infiltration, obliterative phlebitis, lymphoid follicles, perineural inflammation, and immunoglobulin G4 (IgG4) plasma cell infiltration, consistent with a contained ruptured aneurysm associated with IgG4 periaortitis.	21944481
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	The purpose of this study was to identify local differences in inflammation and tissue degradation within the circumference of the abdominal aortic aneurysm (AAA).	21944916
HD Term Type, Inflammation	Altered Intercellular Communication	IL-21 is decreased in HD patients and is not affected by gender, age, inflammation, the vintage of HD, type of medication and type of used dialysis membrane.	21945025
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	TH1 and TH17 interactions in untreated inflamed mucosa of inflammatory bowel disease, and their potential to mediate the inflammation.	21945121
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Recently, a TH17 lineage has been introduced, but their role in the inflammation of CD and UC is not fully understood.	21945121
Inflammation, Cerebral Infarction	Altered Intercellular Communication	To investigate the effect of anti-Helicobacter pylori on the inflammation mediators and prognosis in patients with acute cerebral infarction.	21946199
Communicable Diseases, Inflammation	Altered Intercellular Communication	C-reactive protein (CRP) is a nonspecific parameter for infection and inflammation but might be employed as a trigger for diagnosis.	21947022
Communicable Diseases, Chemotherapy-Induced Febrile Neutropenia, Inflammation	Altered Intercellular Communication	(18)F-FDG PET/CT scanning during chemotherapy-induced febrile neutropenia and increased CRP is able to detect localized foci of infection and inflammation despite the absence of circulating neutrophils.	21947022
Inflammation	Altered Intercellular Communication	Associated chronic inflammation had resulted in the huge keloids.	21947163
Inflammatory abnormality of the eye	Altered Intercellular Communication	In addition, fungal DNA was also not detected in patients without ocular inflammation (controls).	21947326
Inflammation, Hypertriglyceridemia	Altered Intercellular Communication	Our data suggests that a hypertriglyceridemic state is associated with hs-CRP irrespective of BMI, LDL-C, and HDL-C, indicating that hs-CRP might represent chronic inflammation induced by hypertriglyceridemia in Japanese men with normal glucose tolerance.	21948178
Inflammatory abnormality of the eye	Altered Intercellular Communication	Although the costimulatory molecule OX40 promotes T-cell function and expansion, it is unclear whether OX40 is implicated in ocular inflammation.	21948545
Optimism, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Optimism in relation to inflammation and endothelial dysfunction in older men: the VA Normative Aging Study.	21949417
Inflammation, Endothelial dysfunction, Coronary heart disease	Altered Intercellular Communication	Higher overall optimism scores were associated with lower levels of inflammation and endothelial dysfunction in older men free of coronary heart disease.	21949417
Non-alcoholic Fatty Liver Disease, Hepatitis	Altered Intercellular Communication	In severe NAFLD patients, FGF21 concentration might decrease due to liver inflammation or injury.	21949781
Catapres, Inflammation, Pain Distress Question	Altered Intercellular Communication	She was taking Arthrotec (a combination of diclofenac and misoprostol - for pain and inflammation), Fosamax Plus D (alendronate with vitamin D3 - recently prescribed because of low bone density), and Catapres (clonidine - for menopausal symptoms).	21951026
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Amyloid plaques dissociate pentameric to monomeric C-reactive protein: a novel pathomechanism driving cortical inflammation in Alzheimer's disease?	21951392
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Beta-amyloid (Ab) plaques and local inflammation are central to the pathogenesis of Alzheimer's disease.	21951392
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	We hypothesized that Ab plaques induce the dissociation of pCRP to individual monomers (mCRP), which possess strong pro-inflammatory properties not shared with pCRP and localizing inflammation to Alzheimer's plaques.	21951392
Alzheimers Disease", Inflammation	Altered Intercellular Communication	The existence of mCRP but not pCRP in the brains of Alzheimer's disease patients strongly indicates that this newly described biological effect of Ab plaques is relevant in Alzheimer pathobiology; potentially localizing and amplifying inflammation via the strong pro-inflammatory effects of locally generated mCRP.	21951392
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Anti-cyclic citrullinated peptide antibodies (ACPA) seem to be produced locally at the site of joints inflammation in the first stage of rheumatoid arthritis (RA).	21952975
Inflammation, AAVS1 gene, Vasculitis, CTCAE	Altered Intercellular Communication	To identify biomarkers that distinguish between active antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and remission in a manner superior or complementary to established markers of systemic inflammation.	21953143
Inflammation	Altered Intercellular Communication	This study was undertaken to investigate the significance of residual inflammation in remission in relation to radiographic progression.	21953215
Inflammation, Arteritis	Altered Intercellular Communication	SVV was defined as inflammation of the small vessels external to the temporal artery adventitia, and VVV was defined as isolated inflammation of temporal artery vasa vasorum.	21953306
Inflammation, Coronary Artery Disease, Angina Pectoris	Altered Intercellular Communication	Reduced activity of systemic inflammation had a beneficial effect on the course of coronary artery disease (significant decrease in the functional class of stable angina).	21954641
vascular inflammations, Metabolic Syndrome X	Altered Intercellular Communication	Our data show that patients with the metabolic syndrome given a statin/TZD combination manifest greater reductions in markers of vascular inflammation and oxidant stress, 24-h ambulatory BP and increases in adiponectin as well as improved glycaemic indices.	21955403
Uveitis	Altered Intercellular Communication	All eyes showed no clinical signs of postoperative intraocular inflammation.	21955552
Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	Effects of conventional versus biocompatible peritoneal dialysis solutions on peritoneal and systemic inflammation, malnutrition and atherosclerosis in CAPD patients.	21955867
Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	Chronic inflammation, malnutrition and atherosclerosis (MIA syndrome) are important predictors of high mortality in continuous ambulatory peritoneal dialysis (CAPD) patients.	21955867
Inflammation	Altered Intercellular Communication	All patients underwent echocardiography and B-mode ultrasonography of common carotid arteries together with assessments of nutrition status and parameters of systemic and local inflammation.	21955867
Inflammation, Glioblastoma Multiforme Pathway	Altered Intercellular Communication	The postoperative therapy and the inflammation might have contributed to the severe change in morphological phenotype of the glioma.	21955926
Inflammation	Altered Intercellular Communication	Inflammation can affect the ventricles with an unknown mechanism, and QTc may be slightly prolonged as a result in the active phase of AS.	21955979
Orbital Pseudotumor, Blepharoptosis	Altered Intercellular Communication	Lyme-associated orbital inflammation presenting as painless subacute unilateral ptosis.	21956017
Lyme Disease, Orbital Pseudotumor	Altered Intercellular Communication	Lyme disease should be included in the differential diagnosis of orbital inflammation, especially in Lyme-endemic areas.	21956017
Inflammation, Atopy	Altered Intercellular Communication	Pediatric inflammatory vulvitis (PIV) is clinically characterized by itching, soreness and inflammation and can be due to both an infective process and a non-specific irritative process, especially in atopic patients.	21956267
Hypoestrogenism, Hypothalamic amenorrhea	Altered Intercellular Communication	Functional hypothalamic amenorrhea (FHA) related to hypoestrogenism and hormonal status may influence skeletal homeostasis and body composition.	21957879
Arterial Stiffness, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The association of specific metabolites of lipid metabolism with markers of oxidative stress, inflammation and arterial stiffness in men with newly diagnosed type 2 diabetes.	21958081
Arterial Stiffness, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus	Altered Intercellular Communication	To determine whether circulating metabolic intermediates are associated with inflammation, oxidative stress and arterial stiffness in men with newly diagnosed type 2 diabetes and investigate the circulating metabolic intermediates that may predict the risk of developing diabetes.	21958081
Arterial Stiffness, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Circulating lipid-related intermediate metabolites can be closely associated with inflammation, oxidative stress and arterial stiffness in early diabetes.	21958081
hearing impairment, Communicable Diseases, Inflammation, Ear Inflammation	Altered Intercellular Communication	Hearing loss was related to otitis (odds ratio [OR], 2.58; 95% confidence interval [CI], 1.66-4.02; p < 0.001) and inversely related to serotype 23 F infection (OR, 0.36; 95% CI, 0.13-0.98; p = 0.025), but not with parameters of disease severity or indicators of cerebrospinal fluid inflammation severity.	21958295
hearing impairment, Ear Inflammation	Altered Intercellular Communication	Otitis and resulting perilympathic inflammation contribute to meningitis-associated hearing loss.	21958295
Inflammation	Altered Intercellular Communication	The patient was given high-dose antibiotics due to the secondary inflammation involving the parietal peritoneum.	21959616
Inflammation, Primary malignant neoplasm, Psychological Distress	Altered Intercellular Communication	The aim of this study was to investigate the potential correlations between nutritional status, systemic inflammation, and psychological distress in cancer patients.	21959842
Inflammation, Anxiety, CTCAE 3.0, Depression, CTCAE	Altered Intercellular Communication	Mini Nutritional Assessment (MNA) was used for the evaluation of nutritional status, Glasgow Prognostic Score (GPS) for the estimation of systemic inflammation, and Hospital Anxiety and Depression Scale (HADS) for psychological assessment.	21959842
Inflammation	Altered Intercellular Communication	Probably, central venous catheters (CVCs) contribute to this resistance by inducing inflammation and oxidative stress.	21960369
Inflammation, Dental Plaque	Altered Intercellular Communication	We hypothesized that microbubbles are retained in areas of plaque inflammation, aiming to examine whether LP-CEUS signal reflects plaque biology.	21960570
Inflammation, Rupture	Altered Intercellular Communication	LP-CEUS reflects biological features of inflammation and angiogenesis, key features predisposing to plaque rupture.	21960570
Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	Further investigation of LP-CEUS as a tissue-specific marker of inflammation for risk stratification of carotid atherosclerosis is warranted.	21960570
Inflammation	Altered Intercellular Communication	The most common reason for open conversion was severe acute inflammation (38.7%).	21962732
Inflammation	Altered Intercellular Communication	Older patients have a higher likelihood of conversion with severe acute inflammation being the most common reason for conversion.	21962732
Inflammation, Aortic Aneurysm	Altered Intercellular Communication	Inflammation is associated with the formation of aortic aneurysm.	21962843
vascular inflammations, Arterial aneurysm	Altered Intercellular Communication	The Cys-X-Cys chemokine receptor 3 receptor is necessary for vascular inflammation and the formation of arterial aneurysms in mice.	21962843
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	Chronic inflammation has been reported to be associated with the pathogenesis of BPH and lower urinary tract symptoms (LUTS).	21962879
Inflammation	Altered Intercellular Communication	Chronic inflammation may play a role in the occurrence of residual urgency in BPH patients.	21962879
Pain Distress Question, Inflammation, Complication Aspects, Ocular Hypertension, Peripheral ulcerative keratitis, Uveitis	Altered Intercellular Communication	Clinical features (pain, scleral inflammation), ocular complications (decrease in vision, anterior uveitis, peripheral ulcerative keratitis, ocular hypertension), and disease associations.	21963265
Inflammation, Necrotizing Scleritis, Ocular Hypertension, Scleritis, Uveitis	Altered Intercellular Communication	Risk factors for decrease in vision in patients with scleritis included necrotizing scleritis (odds ratio [OR], 6.63; P<0.001), posterior scleritis (OR, 2.33; P = 0.042), degree of scleral inflammation of more than 2+ (range, 0-4+; OR, 3.60; P<0.001), anterior uveitis (OR, 1.78; P = 0.033), ocular hypertension (OR, 3.19; P<0.001), and associated disease (OR, 2.66; P<0.001), mainly infectious (OR, 4.44; P<0.001).	21963265
Inflammation, Necrotizing Scleritis, Ocular Hypertension, Communicable Diseases, Scleritis, Uveitis	Altered Intercellular Communication	Risk factors for decrease in vision in patients with scleritis include necrotizing scleritis, posterior scleritis, scleral inflammation of more than 2+, anterior uveitis, ocular hypertension, and associated infectious disease.	21963265
Communicable Diseases, Inflammation	Altered Intercellular Communication	Postoperatively, patients were followed for improvement in Snellen visual acuity, control of inflammation, and development of complications such as infection or uncontrolled intraocular pressure in the eyes.	21963487
Refractory anemias, Inflammation, Atherosclerosis	Altered Intercellular Communication	These prospective data provide evidence that inflammation is a contributor to the progression of subclinical atherosclerosis in RA and that it is potentially modified favorably by TNF inhibitors and detrimentally by glucocorticoids.	21965129
Inflammation, Hypertensive (finding), Damage, Obesity	Altered Intercellular Communication	The effect of inflammation on the development of hypertensive end organ damage may be associated with obesity, so that control of obesity may eliminate the inflammatory state in hypertensive patients and also hypertensive end organ damage.	21966945
Inflammation, osteoclast activating factor	Altered Intercellular Communication	Several factors are linked to postoperative AF (POAF), including advanced age and systemic inflammation.	21967453
Barrett Esophagus, Inflammation	Altered Intercellular Communication	Use of aspirin was not associated with nondysplastic Barrett's oesophagus when compared with population (OR=1.01, 95% CI 0.71-1.43) or inflammation controls (OR=1.16, 95% CI 0.80-1.68).	21967506
Autosomal Recessive Disorder, Inflammation, Cognitive disability, Vascular Diseases	Altered Intercellular Communication	Dysmorphic features, cognitive disability, chronic inflammation, and predisposition to vascular disease in two sisters: a new autosomal recessive disorder?	21968521
Inflammation, Carcinogenesis	Altered Intercellular Communication	Oxidative damage by reactive oxygen species (ROS) plays a major role in skin aging, carcinogenesis and inflammation.	21968658
Inflammation, Necrosis	Altered Intercellular Communication	However, additional studies are necessary to determine the clinical utility of GTE for decreasing skin cell ROS, necrosis and inflammation.	21968658
Inflammation	Altered Intercellular Communication	Interleukin-17-positive mast cells contribute to synovial inflammation in spondylarthritis.	21968742
Inflammation	Altered Intercellular Communication	We therefore undertook the present study to investigate the potential contribution of mast cells to synovial inflammation in SpA.	21968742
Inflammation	Altered Intercellular Communication	The specific and TNF-independent increase in IL-17-expressing mast cells may contribute to the progression of synovial inflammation in peripheral SpA.	21968742
Doxorubicin/Thiotepa/Vinblastine, Inflammation, Aortic Aneurysm	Altered Intercellular Communication	Immune response activation solely in the aortic media of TAV patients suggests that inflammation is involved in TAA formation in TAV but not in BAV patients.	21968790
Inflammation, Sarcopenia	Altered Intercellular Communication	Measures of sarcopenia are associated with lower cognitive functioning in older adults, and for females, this association may be partly due to systemic inflammation.	21968867
Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Induction of vascular GTP-cyclohydrolase I and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis.	21969008
Inflammation, Vascular Diseases	Altered Intercellular Communication	We hypothesized that induction of BH4 synthesis might be an endothelial defense mechanism against inflammation in vascular disease states.	21969008
Inflammation, Salmonella typhi	Altered Intercellular Communication	In Study 1, 20 healthy individuals were randomized to receive Salmonella typhi vaccine (a model of acute inflammation) or placebo in a double-blind study.	21969008
Inflammation	Altered Intercellular Communication	The ability to increase vascular GCH1 expression and BH4 synthesis in response to inflammation preserves endothelial function in inflammatory states.	21969008
Endothelial dysfunction	Altered Intercellular Communication	These novel findings identify BH4 as a vascular defense mechanism against inflammation-induced endothelial dysfunction.	21969008
Myocarditis	Altered Intercellular Communication	Pericardial inflammation may be a marker for reversibility.	21969014
Pericardial sac structure, Inflammation	Altered Intercellular Communication	Antiinflammatory therapy was associated with a reduction in pericardial and systemic inflammation and LGE pericardial thickness, with resolution of CP physiology and symptoms.	21969014
Overactive Bladder	Altered Intercellular Communication	Dysregulation of neurotransmitter receptors may contribute to bladder overactivity (OAB) symptoms.	21969132
Cholangiocarcinoma, Fibrosis Assessment, Intrahepatic bile duct, interstitial	Altered Intercellular Communication	It is speculated that peribiliary gland involvement by superficially spreading bile duct cancer and subsequent obstructive glandular inflammation with fibrosis might cause intrahepatic bile duct strictures even without interstitial cancer invasion.	21969205
Inflammation	Altered Intercellular Communication	MRI of her thigh muscles revealed serpiginous increased T-2 signals consistent with inflammation and a complex round mass in the left pelvis.	21969283
Minimal Disseminated Disease, Anhedonia, Depressive disorder	Altered Intercellular Communication	Anhedonia, a core symptom of major depressive disorder (MDD) and highly variable among adolescents with MDD, may involve alterations in the major inhibitory amino acid neurotransmitter system of g-aminobutyric acid (GABA).	21969419
Minimal Disseminated Disease, Anhedonia	Altered Intercellular Communication	These findings suggest that GABA, the major inhibitory neurotransmitter in the brain, may be implicated in adolescent MDD and, more specifically, in those with anhedonia.	21969419
Inflammation, Loading Technique	Altered Intercellular Communication	Our results suggest that plasma 24S-OH-Chol levels might be increased in the first stages of LOAD, and this phenomenon might be related with systemic inflammation.	21970714
Celiac Disease, Inflammation	Altered Intercellular Communication	Children with celiac disease (CD) are at risk for decreased bone mineral density (BMD) because of fat-soluble vitamin malabsorption, inflammation and/or under-nutrition.	21970944
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Chemerin is an adipokine associated with metabolic syndrome, systemic inflammation and innate immune system.	21971116
Alzheimers Disease", millicurie, Inflammation	Altered Intercellular Communication	In a total of 205 people with MCI, 77 of whom subsequently converted to Alzheimer's disease, we find biochemical markers of inflammation to be better predictors of conversion than APOE genotype or clinical measures (Area under the curve (AUC) 0.65, 0.62, 0.59 respectively).	21971479
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	As rheumatoid arthritis (RA) occurs more often in women than in men, it has been suggested that reproductive hormones may play an important role in the pathogenesis.	21972241
Inflammation, Thrombosis, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Intracardiac expression of markers of endothelial damage/dysfunction, inflammation, thrombosis, and tissue remodeling, and the development of postoperative atrial fibrillation.	21972893
Atrial Fibrillation, Inflammation	Altered Intercellular Communication	LAA and RAA tissue was excised during CABG in 100 patients free of AF and inflammation.	21972893
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Changes in thrombin generation, fibrinolysis, platelet and endothelial cell activity, and inflammation following endovascular abdominal aortic aneurysm repair.	21975058
APP gene, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Abdominal aortic aneurysm (AAA) is a chronic inflammatory condition associated with a prothrombotic, hypofibrinolytic diathesis that may increase the risk of cardiovascular events.	21975058
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Prognosis of patients with colorectal cancer (CRC) is associated with systemic inflammation, and anti-inflammatory drugs can reduce both CRC incidence and mortality.	21976545
Toxic effect, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Dose-limiting toxicities (stomatitis/mucosal inflammation events) were reported in the 800 mg (n = 1), 1200 mg (n = 1), and 1600 mg (n = 2) groups.	21976672
Inflammation, Leukopenia	Altered Intercellular Communication	The most commonly reported grade >= 3 events were febrile neutropenia (n = 24) and stomatitis/mucosal inflammation (n = 16).	21976672
Chronic Kidney Diseases	Altered Intercellular Communication	Ang-2 levels are associated with systemic markers/mediators of micro-inflammation in CKD patients.	21976741
Inflammation, Hypertension, CTCAE, Obesity	Altered Intercellular Communication	Lipocalin-2 is recently recognized as a biomarker of obesity and inflammation, which are both risk factors for hypertension.	21978028
Delirium, Inflammation	Altered Intercellular Communication	The purpose of this study was to investigate whether increased cerebral inflammation with microglial, astrocyte, and cytokine activation exists in patients with delirium compared to nondelirious patients.	21978081
Gastrointestinal inflammation	Altered Intercellular Communication	Intestinal inflammation was strongly associated with these elevations as they were absent during remission and significantly reduced with anti-inflammatory treatment.	21978578
Inflammation, Burn injury, Edema	Altered Intercellular Communication	Oxidative stress and inflammation generate edema in burns.	21978796
Inflammation, Metabolic Syndrome X, MS gene	Altered Intercellular Communication	No information is available on its presence in human adipocytes and its potential involvement in the chronic inflammation associated with metabolic syndrome (MS).	21978920
Inflammation, Atherosclerosis	Altered Intercellular Communication	Analysis of the leukocyte transriptome, in particular the Finkel-Biskis-Jinkins Osteosarcoma (c-Fos) gene, which has a prominent role in inflammation, provides new insights into atherosclerosis mechanisms.	21978922
Inflammation, Tooth Loss, Obesity	Altered Intercellular Communication	Obesity induced inflammation may promote periodontal tissue destruction and bone resorption inducing tooth loss.	21979390
Inflammation, Intracranial Aneurysm	Altered Intercellular Communication	Chronic inflammation is postulated as an important phenomenon in intracranial aneurysm wall pathophysiology.	21980208
airway disease, Inflammation	Altered Intercellular Communication	Previously, we have shown in other upper and lower airway diseases that immunoglobulin free light chains (FLCs) are increased and may be involved in initiating a local inflammation.	21980441
Pyelonephritis, Communicable Diseases, Chronic obstruction, Nephrolithiasis, NEXMIF gene	Altered Intercellular Communication	Xanthogranulomatous pyelonephritis (XPN) is a rare inflammatory condition usually secondary to chronic obstruction caused by nephrolithiasis and resulting in infection and irreversible destruction of the renal parenchyma.	21980741
Inflammation	Altered Intercellular Communication	As a result, the negative feedback regulation loop with miR-146a involving down-regulation of inflammation factors was interrupted in aged mice.	21981419
Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes inflammation and, in many cases, destruction of the joints.	21981664
Inflammation, Obesity, Atherosclerosis	Altered Intercellular Communication	Given these properties, chemerin may provide an interesting link between obesity, inflammation and atherosclerosis.	21981776
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Chronic low-grade inflammation is a possible risk factor for cancer that may be modifiable with long-term exercise.	21982875
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Marked systemic inflammation associated with acute coronary syndrome was reduced by 1-month therapy with high dose atorvastatin.	21983801
Inflammation, Malnutrition, Anemia	Altered Intercellular Communication	In addition, data on age, sex, disability status, comorbidities, anemia control, malnutrition and inflammation, calcium-phosphorus metabolism and hospitalization rate were collected.	21983989
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	von Willebrand factor and CECs (both P < 0.05) were significantly elevated in EA suggesting endothelial dysfunction and damage but were unrelated to classical laboratory markers of inflammation C-reactive protein, erythrocyte sedimentation rate or IL6.	21985471
Inflammation, Arthritis	Altered Intercellular Communication	Endothelial damage/dysfunction is present early in the course of inflammatory arthritis but is not directly related to inflammation markers.	21985471
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	: TNF-a mediated inflammation is thought to play a key role in the respiratory and systemic features of Chronic Obstructive Pulmonary Disease.	21985478
Inflammation	Altered Intercellular Communication	Thickening of the intimal layer of arteries characterized by expression of smooth muscle a-actin (SMaA), collagen deposition, and inflammation is an important pathophysiological change with aging assumed to be mediated by smooth muscle cells migrating from the medial layer.	21985896
Intraocular inflammation	Altered Intercellular Communication	This was followed by an acute increase in intraocular pressure (IOP) to 60 mm Hg despite open angles, no evidence of intraocular inflammation, and no corticosteroid use.	21986163
Inflammation, Weight decreased, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Baseline insulin-like growth factor-I plasma levels, systemic inflammation, weight loss and clinical outcome in metastatic non-small cell lung cancer patients.	21986483
Inflammation, Primary malignant neoplasm, Weight decreased	Altered Intercellular Communication	Cancer patients frequently suffer from weight loss and systemic inflammation in the context of advanced disease, which is related to adverse outcome.	21986483
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	IGF-I correlates with systemic inflammation and seems to play an independent predictive role in metastatic non-small cell lung cancer.	21986483
Unknown (origin) (qualifier value), Inflammation	Altered Intercellular Communication	Although previous large-vessel arteritis cannot be absolutely excluded, a diagnosis of idiopathic MAS was made, given the absence of any other clinical signs of inflammation (C-reactive protein <0.5 mg/dl; erythrocyte sedimentation rate 5 mm/h).	21986626
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Systemic inflammation and prediction of chemotherapy outcomes in patients receiving docetaxel for advanced cancer.	21986674
Inflammation, Vasogenic Edema	Altered Intercellular Communication	Two patients in the 200-mg group showed transient and focal areas of inflammation or vasogenic edema on magnetic resonance imaging scans at sites with the highest level of amyloid reduction.	21987394
Inflammation	Altered Intercellular Communication	Autophagy is a process of central importance for maintaining cell homeostasis, survival, and the regulation of inflammation.	21987459
Acute and chronic inflammation	Altered Intercellular Communication	We provide a model of how a dysfunction of the CD susceptibility genes, PTPN2 and/or ATG16L1, may contribute to the onset and perpetuation of chronic intestinal inflammation.	21987459
palladium, Inflammation, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	The majority of these differentially expressed proteins are known to be involved in processes that have been implicated in the pathogenesis of PD previously, including mitochondrial dysfunction, oxidative stress, protein misfolding, cytoskeleton dysregulation and inflammation.	21988495
Multiple Organ Failure, Inflammation, Respiratory Distress Syndrome, Adult, Inflammatory, Fracture	Altered Intercellular Communication	Systemic inflammation in response to a femur fracture and the additional fixation is associated with inflammatory complications, such as acute respiratory distress syndrome and multiple organ dysfunction syndrome.	21988742
Inflammation, Traumatic injury	Altered Intercellular Communication	This study intents to identify C1-esterase inhibitor as a safe and potent anti-inflammatory agent, that is capable of suppressing systemic inflammation in trauma patients.	21988742
Inflammation	Altered Intercellular Communication	This might facilitate early total care procedures by lowering the risk of inflammation in response to the surgical intervention.	21988742
Inflammation, Illness Behavior, Fatigue	Altered Intercellular Communication	Prior work has suggested that fatigue may be related to inflammation and its associated sickness behaviors; accordingly, our findings may be tapping into this same physiological substrate.	21988771
Inflammation	Altered Intercellular Communication	Local inflammation was more frequently noted when catheters were colonized (26.9% [95% CI, 15.2%-38.7%] versus 8.1% [95% CI, 4.2%-11.9%], P = 0.005).	21989151
Inflammation, Sarcopenia	Altered Intercellular Communication	Chronic inflammation is one of the most important physiologic correlates of the frailty syndrome and high levels of proinflammatory cytokines, related to both aging and increasing adiposity in older individuals are related to an increased risk of mortality, sarcopenia, reduced muscle strength and decreased mobility.	21989337
Inflammation, Muscle (organ)	Altered Intercellular Communication	The purpose of this narrative review is to inform the physical therapist of the effects of aging and increasing adiposity on chronic inflammation and the association of inflammation with muscle loss, strength, and mobility impairments in older adults; and to review the current evidence to provide clinical recommendations on physical activity and exercise regimes that may mitigate chronic inflammation in older adults.	21989337
Inflammation	Altered Intercellular Communication	Exercise is a potent preventive intervention strategy and countermeasure for chronic inflammation and adiposity.	21989337
Inflammation	Altered Intercellular Communication	Exercise can also benefit the frail older individual by combating the negative effects of chronic inflammation and optimally balancing the production of pro and anti-inflammatory cytokines.	21989337
Inflammation, muscle mass	Altered Intercellular Communication	In addition to providing an anti-inflammatory environment within muscle to mitigate the effects of chronic inflammation, exercise has the added benefit of improving muscle mass and function and decreasing adiposity in older adults.	21989337
Frailty	Altered Intercellular Communication	Frailty, a predisability condition with links to chronic inflammatory conditions, is estimated to affect 7% of individuals older than 60 years and 40% of people older than 80 years.	21989337
Degenerative polyarthritis, Inflammation, Vascular Alterations	Altered Intercellular Communication	Besides biomechanical mechanisms, the pathogenesis of osteoarthritis may involve inflammation, vascular alterations and dysregulation of lipid metabolism.	21989540
Inflammation	Altered Intercellular Communication	Whether this is due to burn-out of inflammation in late disease must be investigated further.	21989543
vascular inflammations, Optic Neuropathy, Ischemic	Altered Intercellular Communication	Our findings indicate that local expression of PTX3 is a feature of vascular inflammation in GCA; elevated circulating levels of PTX3 identify patients with very recent optic nerve ischemia or a recent diagnosis.	21989653
Inflammation, Takayasu Arteritis	Altered Intercellular Communication	The assessment of disease activity in Takayasu arteritis (TA) is difficult in clinical situations because clinical symptoms and laboratory parameters do not always reflect the actual inflammation of the arterial wall.	21989701
Inflammation	Altered Intercellular Communication	The intended delivery of AIS into the inflamed tissue could alleviate tissue destruction taking place during chronic inflammation, as well as facilitate the termination of these processes.	21990110
Fibrosis Assessment	Altered Intercellular Communication	Bioactive polyglycolic/polylactic acid (PGLA)-coated Matrix detachable coils were reported to incite intra-aneurysmal inflammation and fibrosis.	21990437
Inflammation, Dental Plaque, Calcinosis	Altered Intercellular Communication	Inflammation and angiogenesis are hypothesized to be important factors contributing to plaque vulnerability, whereas calcification is suggested to confer stability.	21990578
Inflammation, Dental Plaque, Calcinosis	Altered Intercellular Communication	We provide in vivo evidence that increased plaque metabolism is associated with increased biomarkers of angiogenesis and inflammation, whereas plaque calcification is inversely related to PET and histologic biomarkers of inflammation.	21990578
Inflammation, Nasal Polyps, Craniosynostosis	Altered Intercellular Communication	The majority of patients with CRS with nasal polyps (CRS with NP) are characterized by predominantly eosinophilic inflammation.	21991563
Craniosynostosis	Altered Intercellular Communication	However, Asian patients with CRS with NP show characteristics indicative of neutrophilic inflammation.	21991563
Inflammation, Craniosynostosis	Altered Intercellular Communication	Eosinophilic inflammation was found in 59.6% of patients with CRS with NP.	21991563
Balanitis	Altered Intercellular Communication	Plasma cell balanitis (PCB), also knows as Zoon balanitis, is a benign asymptomatic but chronic and erosive inflammatory condition of the glans penis and prepuce that generally affects uncircumcised men in later years.	21992223
Inflammation, Thrombophilia, Corneal Endothelial Cell Loss	Altered Intercellular Communication	Markers of the TF pathway, hypercoagulability, inflammation and endothelial cell damage were measured in plasma.	21993387
Inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Changes to the TF pathway were not associated with manifestations of SLE such as inflammation or endothelial cell damage.	21993387
Acute Lung Injury, Inflammation, Postoperative Complications, Respiratory Distress Syndrome, Adult	Altered Intercellular Communication	The con-tinuous improvement of surgical techniques has led to a decrease in surgical complications, whereas up to 30% of the patients develop postoperative pulmonary complications such as acute lung injury (ALI) or even the more severe acute respiratory distress syndrome (ARDS), which are characterized by an acute inflammation in the lung parenchyma and the airspace.	21993488
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Renal resistive index and low-grade inflammation in patients with essential hypertension.	21993489
Inflammation, Nephritis, Tubulointerstitial, Hypertension, CTCAE	Altered Intercellular Communication	In essential hypertension low-grade inflammation is associated with tubulo-interstitial damage evaluated by Doppler ultrasonography.	21993489
Granulomatous inflammation	Altered Intercellular Communication	However, bacteriological confirmation is essential because of the presence of various granulomatous inflammation.	21994193
Inflammation, Arteriopathic disease	Altered Intercellular Communication	The genotype may have an effect on systemic MMP-8 levels which could not, however, be seen in the arterial disease patients probably as a result of the strong inflammation involved in the disease pathogenesis.	21994255
Periodontal Diseases, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation associated with periodontal diseases, characterized by elevated pro-inflammatory cytokines, innate immune receptor expression, and cellular infiltrate was exacerbated in patients with T2D.	21996642
Inflammation, Hyperglycemia	Altered Intercellular Communication	In addition, a feed forward loop regulated by poor glycemic control was associated with a loss of mucosal barrier integrity and accumulation of innate immune receptor ligands resulting in an exacerbation of ongoing inflammation, where RAGE and TLR4 cooperated to induce responses in oral epithelial cells, which were exacerbated by hyperglycemia.	21996642
Inflammation, Pancreatitis	Altered Intercellular Communication	Acute pancreatitis is a form of inflammation with clinical features ranging from pancreatic inflammation to fatal systemic manifestations.	21997439
Inflammation, Endosalpingiosis	Altered Intercellular Communication	We propose a model for the development of ovarian and extraovarian low-grade serous proliferations (APST, noninvasive epithelial implants, and endosalpingiosis) that postulates that all of these lesions are derived from PTH, which appears to be induced by chronic inflammation.	21997682
Pneumonitis	Altered Intercellular Communication	Groups were initially compared for survival and subsequently for markers of pulmonary inflammation, influx of lymphocytes and neutrophils, and expression of PD-1 and its ligand-PD-L1.	21997806
Autoimmune Diseases, Monoclonal Gammopathy of Undetermined Significance, Infection	Altered Intercellular Communication	A personal history of all infections combined was associated with a significantly increased risk of MM (OR = 1.2; 95% CI, 1.1-1.3), and a personal history of all conditions in the categories infections (OR = 1.6; 95% CI, 1.5-1.7), inflammatory conditions (OR = 1.4; 95% CI, 1.2-1.5), and autoimmune diseases (OR = 2.1; 95% CI, 1.9-2.4) was associated with a significantly increased risk of MGUS.	21998210
Inflammation, Thrombosis, Tacca leontopetaloides	Altered Intercellular Communication	Though systemic inflammation and thrombosis are associated with TIA, further study may provide insight into TIA pathophysiology and possibly lead to the development of treatments specifically targeted to TIA.	21998319
Inflammation	Altered Intercellular Communication	These genes were associated with systemic inflammation, platelet activation, and prothrombin activation.	21998319
Pain Distress Question, Inflammation	Altered Intercellular Communication	Higher pain scores and more inflammation were reported with Nd:YAG laser; however, it was preferred by 29 volunteers (74%).	21999492
Hyperglycemia, Atherosclerosis, Plaque, Atherosclerotic	Altered Intercellular Communication	Although hyperglycemia is associated with an increased risk of atherosclerotic cardiovascular disease, there are no clinical data to show the preference of any specific oral hypoglycemic agents to prevent atherosclerotic plaque inflammation.	21999871
Inflammation	Altered Intercellular Communication	Plaque inflammation was measured by blood-normalized standardized uptake value, known as a target-to-background ratio.	21999871
Inflammation	Altered Intercellular Communication	Multiple stepwise regression analysis revealed that the increase in high-density lipoprotein cholesterol level was independently associated with the attenuation of plaque inflammation.	21999871
Plaque, Atherosclerotic, diabetic	Altered Intercellular Communication	Pioglitazone may be a promising strategy for the treatment of atherosclerotic plaque inflammation in impaired glucose tolerance or diabetic patients.	21999871
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	(Detection of Plaque Inflammation and Visualization of Anti-Inflammatory Effects of Pioglitazone on Plaque Inflammation in Subjects With Impaired Glucose Tolerance and Type 2 Diabetes Mellitus by FDG-PET/CT; NCT00722631).	21999871
hormone deficiency, Precocious Puberty	Altered Intercellular Communication	This syndrome has only once been associated with growth hormone deficiency and precocious puberty in the same patient.	22001135
Acromegaly, Diseases of mitral valve	Altered Intercellular Communication	Valvular disease in patients with acromegaly is associated with hormonal activity, and control of growth hormone and insulin-like growth factor I excesses is important in the long-term durability of mitral valve repair.	22001216
Acromegaly, Diseases of mitral valve	Altered Intercellular Communication	Valvular disease in patients with acromegaly is associated with hormonal activity, and control of growth hormone and insulin-like growth factor I excesses is important in the long-term durability of mitral valve repair.	22001216
Gastritis	Altered Intercellular Communication	Therefore, a lack of effectiveness in eradication therapy can lead to chronic stomach inflammation and promote cancerogenesis.	22001987
Mucous Membrane, polyps, Inflammation	Altered Intercellular Communication	The exact pathogenetic mechanism of polyp formation is unclear although it seems possible that the underlying cause is mucosal injury that is vascular in nature rather than being secondary to surface inflammation.	22002002
Vitritis, Inflammation, Fibrinous	Altered Intercellular Communication	There was a strong anterior segment inflammation with fibrinous exudates and a dense vitritis.	22003760
Inflammation, Asthma, Common Cold, Herpes Labialis	Altered Intercellular Communication	Five subjects reported five adverse events (secondary herpes labialis recurrences, n = 2; infectious rhinitis, n = 1; application site inflammation, n = 1; bronchial asthma, n = 1).	22004219
Inflammation	Altered Intercellular Communication	At the site of inflammation, macrophages and neutrophils are present as well as cytokines such as TNF-a and IFN-g.	22004597
Inflammation, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	There was not a significant association between the degree of the CIN and the staging of the SCC of the cervix and the degree of inflammation as assessed by the levels of inflammatory markers.	22004597
Inflammation, Diego blood group system, Dyskeratosis	Altered Intercellular Communication	Periadnexal inflammation was observed in 12 patients (80%) in the DI group vs 37 (84%) in the non-DI group, and basal layer liquefaction with dyskeratosis was seen in 15 patients (100%) in the DI group and in 37 (84%) in the non-DI group.	22004879
ARCN1 gene, Respiratory physiology, Inflammation	Altered Intercellular Communication	The progressive decline in lung function that occurs in COPD is a result of persistent inflammation of the airways and destruction of the lung parenchyma.	22005302
ARCN1 gene, Inflammation	Altered Intercellular Communication	Despite the key role of inflammation in the pathogenesis of COPD, treatment with corticosteroids - normally highly effective antiinflammatory drugs - has little therapeutic benefit.	22005302
Inflammation, Chronic graft-versus-host disease	Altered Intercellular Communication	Clinical laboratory markers of inflammation as determinants of chronic graft-versus-host disease activity and NIH global severity.	22005783
Stable chronic Graft vs Host Disease, Inflammation	Altered Intercellular Communication	We analyzed clinical markers of inflammation in the sera of patients with established cGVHD and correlated those with definitions of disease activity.	22005783
Stable chronic Graft vs Host Disease, Inflammation	Altered Intercellular Communication	This study identified common laboratory indicators of inflammation that can serve as markers of cGVHD activity and severity.	22005783
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Fucosylation is a crucial oligosaccharide modification in cancer and inflammation.	22006099
Inflammation, Laryngopharyngeal Reflux, Hypertrophy of adenoids, Bacterial Infections	Altered Intercellular Communication	Inflammation and enlargement of the adenoids is not likely due to ongoing bacterial infection arising from laryngopharyngeal reflux.	22006777
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	[The relationship between anaphylatoxin C3a and benign prostatic hyperplasia with inflammation].	22007489
Inflammation, Elastosis perforans serpiginosa	Altered Intercellular Communication	C3a levels in EPS of the BPH patients: severe inflammation group > mild inflammation group > normal control group (all P < 0.01).	22007489
Inflammation, Elastosis perforans serpiginosa	Altered Intercellular Communication	C3a levels in the EPS could be used to determine whether BPH combined inflammation, sensitivity : 0.97, specificity: 0.70.	22007489
Inflammation, Prostate	Altered Intercellular Communication	C3a is an ideal criteria to diagnose prostatic histological inflammation in BPH patients.	22007489
Cessation of life, Inflammation, Organ dysfunction syndrome, Communicable Diseases	Altered Intercellular Communication	The most important and common cause of death for the patients with FP is multiple organ dysfunction syndrome, which usually was the consequence of systemic inflammation response syndrome in the early stage, and the severe infection in the later stage, respectively.	22007499
Inflammation, Aortic Stiffness, Overweight	Altered Intercellular Communication	Serum aldosterone is associated with inflammation and aortic stiffness in normotensive overweight and obese young adults.	22007645
vascular inflammations	Altered Intercellular Communication	Circulating aldosterone may play an important role in vascular inflammation and aortic stiffening in normotensive overweight and obese adults.	22007645
Inflammation, Impaired cognition	Altered Intercellular Communication	These findings suggest that inflammation plays an important role in the development and presence of cognitive impairment.	22008268
Inflammation	Altered Intercellular Communication	Concentration of CSF CXCL10, CXCL11, CXCL12, CXCL13 and serum CXCL10, CXCL13 may be good biomarkers of CNS inflammation caused by TBEV.	22008312
Granulomatous inflammation, Fibrosis Assessment	Altered Intercellular Communication	In these 21 patients, severity of liver-test abnormalities was significantly associated with extensiveness of granulomatous inflammation (r=0.58, P=0.006) and degree of fibrosis (r=0.64, P=0.002).	22008629
Inflammation, Anemia, HIV Infections	Altered Intercellular Communication	Anemia, particularly iron deficiency anemia and anemia of inflammation, is highly prevalent among children with HIV infection.	22009132
Degenerative polyarthritis, Inflammation, Joint swelling	Altered Intercellular Communication	Ultrasound treatment significantly alleviates joint symptoms, relieving joint swelling, increasing joint mobility and reducing inflammation, in osteoarthritis patients.	22009649
Inflammation, KANTR gene, Obstruction, Traumatic injury, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Among the uncommon causes, such as spasm, obstruction, inflammation or trauma of the coronary arteries, carbon monoxide poisoning could be the cause of ACS.	22010452
Inflammation, Chronic heart failure	Altered Intercellular Communication	It was showed that cardiac resynchronization therapy had an impact on systemic inflammation and hormonal status in patients with chronic heart failure during short-term observation.	22010472
Inflammation, Chronic heart failure	Altered Intercellular Communication	It was showed that cardiac resynchronization therapy had an impact on systemic inflammation and hormonal status in patients with chronic heart failure during short-term observation.	22010472
Inflammation, Obesity	Altered Intercellular Communication	Obesity is a state of chronic low-grade inflammation.	22011432
Inflammation, Diabetes Mellitus, Atherosclerosis	Altered Intercellular Communication	Chronic low-grade inflammation is associated with the pathophysiology of both type-2 diabetes and atherosclerosis.	22011432
Inflammation, Obesity	Altered Intercellular Communication	Prevention or reduction of chronic low-grade inflammation may be advantageous in relation to obesity related co-morbidity.	22011432
Inflammation	Altered Intercellular Communication	Histology indicated absence of inflammation in 50 patients (48%).	22011584
Diastolic dysfunction, Inflammation, Hypertension, CTCAE, Heart failure	Altered Intercellular Communication	Changing from an ACEi or ARB to losartan/HCTZ is associated with a reduction in BP, improvement in LV relaxation, improvement in heart failure state and attenuation of systemic inflammation with few adverse effects in patients with hypertension and diastolic dysfunction.	22011686
vascular inflammations, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Few studies are available in human populations investigating involvement of vascular inflammation and oxidative stress-related dysfunctional transformation of high-density lipoprotein (HDL) in establishing cardiovascular disease (CVD) risk.	22011848
vascular inflammations	Altered Intercellular Communication	In conclusion, TSP-4, a matricellular protein involved in regulating vascular inflammation, plays a role in establishing recurrent coronary risk in post-infarction patients with high levels of HDL-C and CRP.	22011848
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	High dietary fiber intake is associated with decreased inflammation and all-cause mortality in patients with chronic kidney disease.	22012132
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease is considered an inflammatory state and a high fiber intake is associated with decreased inflammation in the general population.	22012132
Inflammation, Chronic Kidney Diseases, Kidney Diseases	Altered Intercellular Communication	Here, we determined whether fiber intake is associated with decreased inflammation and mortality in chronic kidney disease, and whether kidney disease modifies the associations of fiber intake with inflammation and mortality.	22012132
Inflammation, Kidney Diseases	Altered Intercellular Communication	The relationship of total fiber with inflammation and mortality differed significantly in those with and without kidney disease.	22012132
Inflammation, Kidney Diseases	Altered Intercellular Communication	Thus, high dietary total fiber intake is associated with lower risk of inflammation and mortality in kidney disease and these associations are stronger in magnitude in those with kidney disease.	22012132
Inflammation, Kidney Diseases	Altered Intercellular Communication	Interventional trials are needed to establish the effects of fiber intake on inflammation and mortality in kidney disease.	22012132
vascular inflammations, Calcinosis	Altered Intercellular Communication	Our results suggest that hemodynamic stress, vascular inflammation and calcification, and matrix remodeling may have a role in the pathogenesis and/or adverse consequences of increased pulse pressure.	22012208
Neoplasms	Altered Intercellular Communication	It is possible that the pattern of Cxs may contribute to tumor formation and growth, as it may indicate aberrant and/or reduced cell-to-cell communication ability.	22012769
Inflammation, Metabolic Syndrome X, Coronary heart disease	Altered Intercellular Communication	The relationships between FAM5C SNP (rs10920501) variability and metabolic syndrome and inflammation in women with coronary heart disease.	22013132
ARCN1 gene, Lung hyperinflation, Inflammation	Altered Intercellular Communication	Dynamic pulmonary hyperinflation and low grade systemic inflammation in stable COPD patients.	22013730
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	It is increasingly recognized that a low grade of systemic inflammation occurs in patients with advanced chronic obstructive pulmonary disease (COPD).	22013730
ARCN1 gene, Lung hyperinflation, DERMATITIS HERPETIFORMIS, FAMILIAL, Inflammation	Altered Intercellular Communication	The aim of the study was to assess if resting dynamic pulmonary hyperinflation (DH) is linked to the presence of systemic inflammation in COPD.	22013730
ARCN1 gene, Lung hyperinflation, Inflammation	Altered Intercellular Communication	These results show that the IC reduction is associated with higher serum levels of CRP in stable COPD patients, suggesting a potential role of dynamic pulmonary hyperinflation on development and maintenance of low grade systemic inflammation in COPD.	22013730
Inflammation, Fibrosis Assessment, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Although mast cells are regarded as important regulators of inflammation and tissue remodelling, their role in cystic fibrosis (CF) and idiopathic pulmonary fibrosis (IPF) has remained less studied.	22014187
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In the alveolar parenchyma in lungs from patients with CF, MCTC numbers increased in areas showing cellular inflammation or fibrosis compared to controls.	22014187
Cerebrovascular Disorders, Inflammation, Impaired cognition	Altered Intercellular Communication	Our findings suggest that inflammation and dysregulation of the fibrynolitic system may be involved in the pathological mechanisms underlying the WM damage seen in cerebrovascular disease and subsequent cognitive impairment.	22014619
Inflammation, Chronic disease	Altered Intercellular Communication	Epidemiological studies have reported associations between circulating inflammation markers and risk of chronic diseases.	22015105
Inflammation, Chronic disease, Hereditary Breast and Ovarian Cancer Syndrome	Altered Intercellular Communication	Our findings suggest that risk factors for chronic diseases (age, BMI, menopausal status, parity, NSAID use, family history of breast and ovarian cancer, and smoking) are associated with inflammation markers in healthy women.	22015105
Herpes Zoster Ophthalmicus, Complication Aspects, Inflammation, Scleritis	Altered Intercellular Communication	Patient characteristics (age, sex); ocular disease characteristics (laterality, type of scleritis, degree of scleral inflammation, ocular complications, delay in presentation, and follow-up period), systemic disease association (associated disease, potentially lethal associated disease); and anti-inflammatory and immunosuppressive medications were studied in patients with scleritis.	22015381
Inflammation, Complication Aspects	Altered Intercellular Communication	Successful response to treatment with NSAIDs was associated with idiopathic diffuse or nodular scleritis with a low degree of scleral inflammation (<= 2+) (odds ratio [OR] = 2.89, P < 0.001) and with idiopathic diffuse or nodular scleritis without ocular complications (OR = 3.13, P < 0.001).	22015381
Inflammation, Simian Acquired Immunodeficiency Syndrome	Altered Intercellular Communication	Successful treatment with SAIDs was associated with idiopathic diffuse or nodular scleritis with a high degree of scleral inflammation (>2+) (OR = 4.70, P = 0.001).	22015381
Inflammation, Complication Aspects	Altered Intercellular Communication	Patients with idiopathic diffuse or nodular scleritis with a low degree of scleral inflammation or without ocular complications may respond to NSAIDs.	22015381
Inflammation, Simian Acquired Immunodeficiency Syndrome	Altered Intercellular Communication	Patients with idiopathic diffuse or nodular scleritis with a high degree of scleral inflammation may respond to SAIDs.	22015381
Inflammation	Altered Intercellular Communication	The reverse dipper circadian pattern is associated with inflammation and constitutes an independent predictor of graft outcome.	22015441
Airway structure, Smooth muscle (tissue), Bronchial Hyperreactivity	Altered Intercellular Communication	Transforming growth factor (TGF) b1 increases pro-inflammatory cytokines and contractile protein expression by human airway smooth muscle (ASM) cells, which could augment airway inflammation and hyperresponsiveness.	22015454
Inflammation, Traumatic injury, Trichilemmal cyst	Altered Intercellular Communication	Proliferating trichilemmal cysts are rare, slowly growing, lobular masses inherited autosomal dominantly and localized on scalps, and believed to arise due to a complication of a trauma and inflammation, and 5-10% of people are reported to be effected.	22016280
Inflammation, Impaired cognition, Failure (biologic function), Trauma, Nervous System	Altered Intercellular Communication	The failure of highly active antiretroviral therapy (HAART) to eliminate cognitive dysfunction in HIV may be secondary to persistence of HIV-infected PBMCs which cross the blood-brain barrier, leading to perivascular inflammation and neuronal injury.	22016479
Inflammation, Weight decreased, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	The objective of the current study was to assess the value of osteopontin as a marker of weight loss in relation to systemic inflammation in non-small cell lung cancer (NSCLC) patients.	22017168
Inflammation, Weight decreased, Carcinoma of lung	Altered Intercellular Communication	In addition to being an indicator of systemic inflammation in lung cancer patients, osteopontin may also be an indicator of weight loss.	22017168
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Association between chronic inflammation and cancer is known and chronic inflammation is one of the characteristics of OLP.	22017396
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	A protein connected to inflammation and suggested to be involved in cancer development is cyclooxygenase-2 (COX-2) which can be inhibited by microRNA-26b (miR-26b).	22017396
Inflammation, Pulmonary Dysfunction	Altered Intercellular Communication	We concluded that inflammation has a close relation with pulmonary dysfunction in hemodialysis patients.	22017533
Inflammation	Altered Intercellular Communication	Inflammation may be a key inciting as well as propagating feature of DP neuropathology.	22017610
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Understanding systemic inflammation, oral hygiene, and cardiovascular disease.	22017776
Carcinoma of anal margin, Infection	Altered Intercellular Communication	Anal squamous cell carcinoma is rare and seems to be associated with chronic inflammatory conditions, infections and immunosuppression.	22018257
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The neutrophil to lymphocyte ratio (NLR), an index of systemic inflammation, is associated with outcome in several cancer types.	22018713
Inflammation, Non-Small Cell Lung Carcinoma, BDI - Functional Impairment	Altered Intercellular Communication	Pre-cachexia in patients with stages I-III non-small cell lung cancer: systemic inflammation and functional impairment without activation of skeletal muscle ubiquitin proteasome system.	22018880
Inflammation, Muscular Atrophy	Altered Intercellular Communication	Preclinical research indicates that systemic inflammation induces cachexia-related muscle wasting through muscular Nuclear Factor-kappa B (NF-kB) signaling and subsequent ubiquitin proteasome system (UPS)-mediated proteolysis.	22018880
Inflammation, Muscular Atrophy, Cachexia	Altered Intercellular Communication	The absence of muscular NF-kB-dependent inflammatory signaling supports the notion that transition of systemic to local inflammation is required to initiate UPS-dependent muscle wasting characteristic for (experimental) cachexia.	22018880
Inflammation, Muscular Atrophy, Cachexia	Altered Intercellular Communication	The absence of muscular NF-kB-dependent inflammatory signaling supports the notion that transition of systemic to local inflammation is required to initiate UPS-dependent muscle wasting characteristic for (experimental) cachexia.	22018880
Inflammation, Blood Vessel, Data types - Address	Altered Intercellular Communication	MPV is an index of platelet activation and may be a potential marker of inflammation to demonstrate the vascular damage in AD.	22019010
Inflammatory Bowel Diseases, Colitis	Altered Intercellular Communication	Colonic inflammation caused by inflammatory bowel disease, which has been suggested to stimulate endogenous nitrosation, did not influence fecal NOC excretion or fecal water genotoxicity.	22019696
Inflammation, Thrombosis, Heart, Brain Injuries	Altered Intercellular Communication	We drew blood soon after admission and measured markers of inflammation, thrombosis, cardiac strain, and cerebral damage.	22020034
Inflammation, Intimal proliferation, Chronic Kidney Diseases, Vascular System Injuries	Altered Intercellular Communication	Inflammation, oxidation and venous neointimal hyperplasia precede vascular injury from AVF creation in CKD patients.	22020525
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Not only does venous IH pre-exist, but inflammation and oxidation markers are present within veins used for the AVF conduit prior to its creation in CKD patients as early as one year before dialysis is commenced.	22020525
Multiple polyps, Inflammation, Tissue Adhesions	Altered Intercellular Communication	Disease recurrence and adverse wound healing in the form of inflammation, polyposis, adhesions, and middle turbinate lateralization may induce suboptimal outcomes following sinus surgery.	22020898
Inflammation, polyps, Tissue Adhesions	Altered Intercellular Communication	Efficacy was assessed by grading inflammation, polyp formation, adhesions, and middle turbinate position.	22020898
Inflammation, Tissue Adhesions	Altered Intercellular Communication	At 1 month, minimal degrees of inflammation and adhesions were observed, suggesting a positive clinical impact of local steroid delivery without evidence of ocular risk.	22020898
Inflammation, Mesenteric Venous Thrombosis, Vasculitis, CTCAE	Altered Intercellular Communication	Pathological examination confirmed chronic inflammation and vasculitis of intestinal connective tissue, combined with the formation of mesenteric vein thrombosis.	22020906
Myocarditis, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	MRI has become the primary tool for assessment of myocardial inflammation in patients with suspected acute myocarditis.	22021499
Inflammation, Chronic heart failure, Metabolic Syndrome X, Congestive heart failure	Altered Intercellular Communication	Gluco-metabolic syndrome, oxidative stress and inflammation are common in chronic heart failure (CHF).	22021702
allergic inflammation	Altered Intercellular Communication	Exhaled nitric oxide is associated with allergic inflammation in children.	22022176
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide (eNO) has been proposed as a noninvasive marker of airway inflammation in asthma.	22022176
Asthma, allergic inflammation, IL13 gene	Altered Intercellular Communication	The purpose of this study was to assess the possible relationship between eNO and allergic inflammation or sensitization in childhood asthma and allergic rhinitis.	22022176
Allergic sensitization, allergic inflammation	Altered Intercellular Communication	This study reveals that eNO level is associated with allergic inflammation and the degree of allergic sensitization.	22022176
Inflammation	Altered Intercellular Communication	Inflammation is thought to play a role in the pathogenesis of major adverse cardiovascular events (MACE).	22022185
Inflammation	Altered Intercellular Communication	It has been suggested that the measurement of markers of inflammation may aid in predicting the risk of such events.	22022185
Inflammation, Bursitis, Traumatic injury, Pain Distress Question	Altered Intercellular Communication	Trochanteric bursitis is a common disorder that is characterized by inflammation of the bursa, superficial to the greater trochanter of the femur, leading to pain in the lateral hip, and often occurs because of acute trauma or repetitive friction involving the iliotibial band, the greater trochanter, and the bursa.	22022680
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	In the elderly, GDF-15 reflects endothelial activation and vascular inflammation and thus, multiple pathways involved in the development and progression of atherosclerosis.	22023041
ARCN1 gene, Inflammation, Left ventricular diastolic dysfunction	Altered Intercellular Communication	In a cross-sectional design we aimed to evaluate the frequency of left ventricular diastolic dysfunction (LVdd) and its correlation with lung function, pulmonary arterial pressure and systemic inflammation in a selected population of COPD at an early stage of their disease.	22023769
Tendinitis, Inflammation, Musculoskeletal Diseases	Altered Intercellular Communication	The differential diagnoses include many musculoskeletal disorders like tendonitis and inflammation of ossicles.	22024638
Inflammation, Pelvic Pain, prostatitis, Pain Distress Question	Altered Intercellular Communication	Importantly, our study showed that OxS is also present in the case of NIH IIIb category prostatitis when the patients have just chronic pelvic pain but no inflammation in prostate-specific materials, as well as in the patients with just lower urinary tract symptoms without pain or overt inflammation.	22025397
Liver carcinoma, Neoplasm Metastasis	Altered Intercellular Communication	The role of polymeric immunoglobulin receptor in inflammation-induced tumor metastasis of human hepatocellular carcinoma.	22025622
Inflammation, Eales disease	Altered Intercellular Communication	Impact of interleukin-6 promoter polymorphism and serum interleukin-6 level on the acute inflammation and neovascularization stages of patients with Eales' disease.	22025890
Inflammation, Mediastinitis	Altered Intercellular Communication	This report describes three rare cases of mediastinitis caused by inflammation of the sternoclavicular joint.	22026087
Inflammation, Primary malignant neoplasm, Fibrosis Assessment, Heart failure, Kidney Diseases, Obesity	Altered Intercellular Communication	Galectin-3 is involved in fibrosis and inflammation and plays a role in heart failure, renal disease, obesity and cancer.	22026577
Inflammation, Liver Dysfunction	Altered Intercellular Communication	In patients undergoing hepatectomy, preoperative immunonutrition reduced inflammation and protected against liver dysfunction.	22027191
Steatohepatitis, Inflammation	Altered Intercellular Communication	Steatohepatitis was observed in seven patients (NAS >= 4) and (1)H MRS was able to predict it with 100% sensitivity and 89% specificity at threshold 10.9%, without knowing lobular inflammation or hepatocyte ballooning.	22027576
Inflammation, Fatty Liver Disease	Altered Intercellular Communication	Serum levels of IL-1RA, and liver mRNA expression of IL1RN are associated with NASH and the degree of lobular inflammation in liver (p<0.05).	22027586
Inflammation, Obesity	Altered Intercellular Communication	The decrease in serum IL-1RA level and expression of IL1RN after obesity surgery correlated with the improvement of lobular inflammation (p<0.05).	22027586
Non-alcoholic Fatty Liver Disease, Fatty Liver Disease	Altered Intercellular Communication	We developed a novel NAFLD Liver Inflammation Score, including serum Il-1RA concentration, which performed better to diagnose NASH than did previously published scores.	22027586
Nutritional Deficiency, Inflammation, Anemia	Altered Intercellular Communication	Many elderly patients have anemia due to nutritional deficiency, chronic inflammation, or comorbid diseases; however, in a significant fraction of the patients with anemia, the cause remains obscure.	22028153
Inflammatory Bowel Diseases, Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Patients with inflammatory bowel disease (IBD) have an increased risk of developing colorectal cancer due to chronic inflammation.	22028324
Inflammatory Bowel Diseases, Inflammation, SLC25A20 gene, Ulcerative Colitis-Associated Colorectal Adenocarcinoma	Altered Intercellular Communication	In IBD, chronic inflammation relies upon a TGFb signaling blockade, but its precise mechanistic relationship to colitis-associated colorectal cancer (CAC) remains unclear.	22028324
Inflammation, Liver carcinoma, Fibrosis Assessment, Hepatitis B, Hepatitis C, FAM126A gene, Liver Cirrhosis	Altered Intercellular Communication	Chronic inflammation caused by hepatitis B virus infection, hepatitis C virus infection, and/or heavy alcohol use can lead to fibrosis, cirrhosis, and eventually hepatocellular carcinoma (HCC).	22028407
Inflammation, Osteitis	Altered Intercellular Communication	Osteitis is associated with worse baseline measures of disease severity and inflammation.	22028948
Inflammation, Atherosclerosis	Altered Intercellular Communication	Lipoprotein-associated phospholipase A2 (LpPLA2) is a lipoprotein-bound enzyme involved in inflammation and atherosclerosis.	22029180
Inflammation, Carcinoma	Altered Intercellular Communication	Carcinomas are considered to be associated with increased cellular proliferation under antigenic stimulation and inflammation.	22029199
Inflammation, Squamous cell carcinoma of the head and neck	Altered Intercellular Communication	Therefore, the markers of increased cellular turnover such as adenosine deaminase and uric acid were estimated quantitatively along with markers of inflammation such as C-reactive protein in squamous cell carcinoma of head and neck region.	22029199
Granulomatous inflammation	Altered Intercellular Communication	A frozen section was taken from 16 patients but not the patient who received a CT-guided peritoneal biopsy, and all revealed granulomatous inflammation.	22030041
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Aortic Stiffness	Altered Intercellular Communication	Aortic stiffness, inflammation, denutrition and type 2 diabetes in the elderly.	22030242
Inflammation, Cerebral Small Vessel Diseases	Altered Intercellular Communication	To clarify the role of inflammation in the pathogenesis of cerebral small vessel disease (SVD), we investigated whether the gene encoding transforming growth factor-beta 1(TGF-beta 1) is a risk factor for cerebral SVD as a whole, and for two different SVD subtypes.	22030425
Inflammation, Hypertensive (finding), Overweight, Obesity	Altered Intercellular Communication	The results suggested that additional cardiovascular risk could be demonstrated by the high prevalence of being overweight and central obesity presented by the population and the presence of subclinical inflammation amongst hypertensive ones.	22030995
Inflammation, Postpoliomyelitis Syndrome	Altered Intercellular Communication	An increase in cytokine in the cerebrospinal fluid suggests that inflammation is pathophysiologically important in post-polio syndrome.	22031351
Arthralgia, Pain Distress Question, Inflammation, Neuralgia	Altered Intercellular Communication	The pain was classified according to the International Association for the Study of Pain criteria as neuropathic when it occurred in an area with decreased sensibility, or nociceptive when signs of inflammation and/or painful joints movements were present.	22031351
NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology, Inflammation, Fever, CTCAE, Vasculitis, CTCAE	Altered Intercellular Communication	We describe the case of an elderly male patient whose presentation with prolonged unexplained fever coupled with cutaneous, pulmonary and other systemic features of inflammation was finally diagnosed as having a primary myelodysplastic syndrome with associated vasculitis after a delay of 4 years.	22031795
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays an important role in the pathophysiology of atherosclerosis.	22032051
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Systemic inflammation and antibodies to citrullinated peptides in hand osteoarthritis.	22032420
Degenerative polyarthritis, Inflammation, 4-hydroxy-2-oxovalerate aldolase activity	Altered Intercellular Communication	To investigate systemic inflammation and autoimmune response to citrullinated peptides in patients with erosive and non erosive 'lone' hand osteoarthritis (HOA) with no hip/knee involvement and their relationship with radiographic structural damage.	22032420
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Our study underlines the lack of systemic inflammation and autoimmunity in 'lone' HOA and confirms the association between BMI and CRP levels.	22032420
Liver carcinoma, Infection, Virus Diseases, Hepatitis B, Hepatitis C, FAM126A gene, Hepatitis, Chronic, Primary Malignant Liver Neoplasm	Altered Intercellular Communication	Hepatocellular carcinoma (HCC) is the most common primary liver cancer, usually arising after years of chronic liver inflammation that could result from viral infections such as hepatitis B virus (HBV) and hepatitic C virus (HCV) infections.	22032643
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD) is a condition associated with inflammation and high levels of uremic toxins and reactive oxygen species.	22032827
Paresis, Fatigue	Altered Intercellular Communication	Inflammation-related muscle weakness and fatigue in geriatric patients.	22032874
Inflammation, Muscular Atrophy	Altered Intercellular Communication	Inflammation in older persons is associated with muscle wasting, leading to frailty and functional decline.	22032874
Chronic heart failure, Chronic inflammation, physiopathological	Altered Intercellular Communication	Chronic heart failure (HF) is characterised by a neurohormonal dysfunction associated with chronic inflammation.	22032915
Airway structure, Lung diseases	Altered Intercellular Communication	These findings indicate that IL-32 facilitates host defense against MAC organisms but may also contribute to the airway inflammation associated with MAC pulmonary disease.	22033195
Inflammation, Virus Diseases, Sensorineural Hearing Loss (disorder)	Altered Intercellular Communication	In addition, the occurrence of SNHL depends on the intensity and duration of the viral infection and inflammation.	22033878
Kidney Failure, Chronic, Inflammation, Cessation of life, Chronic Kidney Diseases	Altered Intercellular Communication	Associations between inflammation and ESRD and death in chronic kidney disease are well established.	22034503
Inflammation, Dysplasia, Ulcerative Colitis, Neoplasms	Altered Intercellular Communication	Whereas AID expression in UC-associated neoplasia was not correlated with the grade of dysplasia, expression in non-neoplastic mucosa of UC was correlated with the histological grade of inflammation.	22034886
Inflammation, Carcinogenesis, Ulcerative Colitis	Altered Intercellular Communication	AID is associated with inflammation in UC, whereas it may not specifically contribute to carcinogenesis in UC.	22034886
Chronic lymphocytic inflammation, Neoplasms	Altered Intercellular Communication	The inverse correlation of tumour buds with peritumoural lymphocytic inflammation suggests an interaction with specific immune responses.	22034888
Inflammation, Data types - Address	Altered Intercellular Communication	This is the first report that shows GMF, a mediator of central nervous system inflammation, is expressed in the brain regions affected in AD and that GMF is mainly localized in reactive astrocytes surrounding APs/NFTs.	22035352
Inflammation, Pustulosis of Palms and Soles, Acne, Synovitis, Osteitis, Musculoskeletal Diseases, Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome, Skin Abnormalities, Hyperostosis	Altered Intercellular Communication	SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, and osteitis) is a rare chronic inflammatory musculoskeletal disorder of unknown etiology observed in children and young adults, which involves both osteo-articular inflammation and skin abnormalities.	22035400
Inflammation, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Histopathology of the liver revealed diffuse granulomatous inflammation with confluent non-caseating granulomas compressing the centrolobular veins.	22035428
Airway structure	Altered Intercellular Communication	The flaw in the study is the higher doses of ICS in the control arms, but the implicit message remains: the essential need for enough ICS to control airway inflammation.	22035511
Inflammation, Squamous cell carcinoma of the head and neck	Altered Intercellular Communication	Loss of TGF-b signaling and PTEN promotes head and neck squamous cell carcinoma through cellular senescence evasion and cancer-related inflammation.	22037217
Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	To do so, we analyzed lung tissue from 21 cases of idiopathic pulmonary fibrosis and 21 (non-fibrotic, non-cancerous) controls for immune cell and inflammation-related markers.	22037258
Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	In summary, our study shows participation of innate and adaptive mononuclear cells in active-disease regions of idiopathic pulmonary fibrosis lung, where the regenerating epithelial cells appear to propagate inflammation.	22037258
Inflammation	Altered Intercellular Communication	Lipid diffusion into the joint cavity, which largely depends on the degree of inflammation, may contribute to modulating local inflammatory processes.	22037510
Inflammation, physiopathological	Altered Intercellular Communication	A senescent phenotype in endothelial cells is associated with increased apoptosis, reduced endothelial nitric oxide synthase (eNOS) and inflammation, which are implicated in arterial dysfunction and disease in humans.	22037549
Inflammation, Hematoma	Altered Intercellular Communication	Chemokines as markers of local inflammation and angiogenesis in patients with chronic subdural hematoma: a prospective study.	22037980
Inflammation	Altered Intercellular Communication	It is likely that these signaling modulators play an important role in promoting local inflammation.	22037980
vascular inflammations	Altered Intercellular Communication	Vascular inflammation and blood pressure response to acute exercise.	22038148
vascular inflammations	Altered Intercellular Communication	The purpose was to examine the association between systemic markers of vascular inflammation and exercise blood pressure (BP) responses.	22038148
Inflammation, Primary malignant neoplasm, Toxic liver disease, Cardiovascular Diseases	Altered Intercellular Communication	Even if the hypothesis of a possible hepatic toxicity of OTA in humans is yet to be verified, the positive association between plasma OTA and CRP may indicate a possible role of OTA in inflammation status and consequently in the genesis of cardiovascular diseases and cancer.	22038465
Inflammation, Spinal Cord Injuries	Altered Intercellular Communication	Fas/FasL-mediated apoptosis and inflammation are key features of acute human spinal cord injury: implications for translational, clinical application.	22038545
Inflammation, Stanford Cancer Institute	Altered Intercellular Communication	We found dramatically reduced inflammation and cytokines and chemokine expression in B6.MRL-Fas-lpr mice compared to Wt mice after SCI.	22038545
Inflammation, Dental Plaque, atherosclerotic	Altered Intercellular Communication	Distribution of inflammation within carotid atherosclerotic plaques with high-risk morphological features: a comparison between positron emission tomography activity, plaque morphology, and histopathology.	22038986
Inflammation, Thrombosis	Altered Intercellular Communication	Although plaque inflammation is also associated with atherothrombosis, the relationship between inflammation and number of HRM is not well understood.	22038986
atherosclerotic	Altered Intercellular Communication	Thirty-four patients underwent (18)flurodeoxyglucose positron emission tomography (FDG-PET) imaging, and carotid atherosclerotic inflammation was assessed (target-to- =0.0003) and increased with the number of HRM observed (P<0.001 for trend).	22038986
Inflammation, atherosclerotic	Altered Intercellular Communication	Similarly, inflammation within atherosclerotic specimens (% CD68 staining) was higher in plaques with (versus without) HRM (median [interquartile range]: 10 [0, 19.85] versus 0 [0, 1.55], P=0.01) and increased with the number of HRM observed (P<0.001 for trend).	22038986
Inflammation	Altered Intercellular Communication	Inflammation, as assessed by both FDG uptake and histology, is increased in plaques containing HRM and increases with increasing number of HRM.	22038986
Inflammation	Altered Intercellular Communication	These data support the concept that inflammation accumulates relative to the burden of morphological abnormalities.	22038986
Refractory anemias, Inflammation, Erosion lesion	Altered Intercellular Communication	This cytokine, as a downstream effector of TNFa and IL-1b, may contribute to inflammation and bone erosions in RA.	22039170
Inflammation	Altered Intercellular Communication	sADAM33 may be a biomarker of lung tissue inflammation and remodelling in sarcoid.	22040125
Gingivitis, Secondary caries, Abnormal color	Altered Intercellular Communication	Baseline and postcementation data were recorded for marginal integrity, marginal discoloration, secondary caries, retention, and gingival inflammation.	22040467
Gingivitis, Hemorrhage, Bone Diseases, Contusions, Petechiae	Altered Intercellular Communication	The condition presents itself by the formation of perifollicular petechiae and bruising, gingival inflammation and bleeding, and, in children, bone disease.	22041118
Inflammation, Sore to touch, Swelling, Inflammatory dermatosis	Altered Intercellular Communication	At midfoot level, clinical examination demonstrated signs suggestive for joint inflammation (tenderness and/or swelling) in at least one joint in 43/200 feet (21.5%) of 23 patients; US showed inflammatory abnormalities in 87/200 feet (43.5%) of 63 patients and structural lesions in 100/200 feet (50%) of 70 patients.	22041178
Nephritis	Altered Intercellular Communication	A number of chemokines and chemokine receptors are produced by intrinsic renal cells as well as by infiltrating cells during renal inflammation.	22041342
Nephritis	Altered Intercellular Communication	The CCR2 chemokine receptor mediates leukocyte chemoattraction in the initiation and amplification phase of renal inflammation.	22041342
Coughing, Inflammation, Chronic cough, MS4A2 wt Allele	Altered Intercellular Communication	FENO could be used as a inflammation marker of chronic cough because of its good correlation with sputum eosinophils, AHR, atopy, and cough symptoms.	22041775
Tears body substance, Inflammation, Keratoconjunctivitis Sicca, Inflammatory disorder	Altered Intercellular Communication	The use of punctal plugs in the treatment of keratoconjunctivitis sicca (KCS) in inflammatory eye disease remains controversial because of the potentially increased retention time of tears enriched with inflammatory cytokines that may aggravate eye inflammation.	22041848
Inflammatory abnormality of the eye	Altered Intercellular Communication	Punctal occlusion achieved a significant improvement in subjective symptoms and objective findings in ocular GvHD without increasing ocular inflammation.	22041848
Inflammation, Caseous necrosis, Granuloma	Altered Intercellular Communication	Various histologic features of nonreactive exudative inflammation were seen, along with granulomas containing Langhans giant cells with or without caseous necrosis in hypervascular organs, such as the lung, liver, and bone marrow.	22041877
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	It produces tumor-like masses of the mesentery composed of varying degrees of fibrosis, chronic inflammation, and fat necrosis.	22042424
Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	This study was designed to investigate the functional heterogeneity of human Th17 and how their plasticity shapes the nature of immune cell responses to inflammation and autoimmune diseases, such as systemic lupus erythematosus (SLE).	22042490
Pneumothorax, Pneumonitis	Altered Intercellular Communication	Effect of ageing and pulmonary inflammation on the incidence and number of cross-bridging structures in pneumothorax patients.	22042982
Inflammation, Obesity	Altered Intercellular Communication	The expression of specific microRNA species in obesity, which could also target and post-transcriptionally modulate cytokine mRNA, provides new insight into possible mechanisms of how risk factors might modify periodontal inflammation and may represent novel therapeutic targets.	22043006
Albumins	Altered Intercellular Communication	Malnutrition inflammation syndrome may contribute to a change of peritoneum, leading to high peritoneal membrane transport, peritoneal albumin loss, and increased glucose uptake into systemic circulation and decreased ultrafiltration (UF) volume.	22043574
Malnutrition	Altered Intercellular Communication	Subjective global assessment score (SGA), malnutrition inflammation score (MIS), and laboratory values were utilized to identify nutritional and inflammatory status.	22043574
Inflammation, Poliovirus Vaccine, Inactivated, Chronic disease	Altered Intercellular Communication	Lifetime occurrence of intimate partner violence (IPV) in women has been associated with increased prevalence of aging-related chronic diseases, including those with a pathophysiology involving inflammation.	22044065
Inflammation	Altered Intercellular Communication	IPV histories remitted for an average of 10 years were associated with biologic mediators of inflammation.	22044065
Inflammation, Dermatitis, Allergic Contact, Hypersensitivity	Altered Intercellular Communication	Allergic contact dermatitis (ACD) is a skin inflammation caused by an allergic reaction after contact with small external substances capable of being absorbed by the skin.	22044472
Inflammation, Thrombophilia	Altered Intercellular Communication	Storage lesions may promote inflammation and thrombophilia when transfused.	22044745
Pancreatitis, AURKAIP1 gene, Autoimmune Pancreatitis, Swelling, Waldenstrom Macroglobulinemia	Altered Intercellular Communication	Autoimmune pancreatitis (AIP), characterized by irregular narrowing of the main pancreatic duct, swelling of the pancreas, and histological evidence of lymphoplasmacytic inflammation by high serum immunoglobulin G4, is distinct from ordinary pancreatitis.	22045429
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation plays a significant role in Alzheimer's disease (AD) pathogenesis.	22045483
Inflammation	Altered Intercellular Communication	We hypothesized that older adults with periodontal inflammation (PI) or many missing teeth would show impaired cognition compared to subjects without PI or with few missing teeth, and among subjects with PI, those with many missing teeth would show impaired cognition compared to those with few missing teeth.	22045483
Inflammation, Hypotension, CTCAE	Altered Intercellular Communication	However, there is some controversy concerning whether antioxidants might attenuate oxidative damage and inflammation in humans after hypotension in the setting of critical illness.	22045831
Paclitaxel Injection Concentrate for Nanodispersion, Sepsis, Fever, Chronic idiopathic neutropenia, Hematological Disease, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Idiopathic chronic neutropenia (ICN) describes a heterogeneous group of hematologic diseases characterized by low circulating neutrophil levels often associated with recurrent fevers, chronic mucosal inflammation, and severe systemic infections.	22047626
Inflammation	Altered Intercellular Communication	The cooling and compression appeared to decrease inflammation, as indicated by a temperature-sensitive decrease in the PGE2 concentration.	22048090
Pain Distress Question, Inflammation	Altered Intercellular Communication	Since PGE2 is a marker of pain and inflammation, the postoperative local cooling and compression appeared to have a positive anti-inflammatory effect.	22048090
Inflammation, Pleurisy, Edema, Granuloma, Foreign-Body, Pleural Effusion, CTCAE	Altered Intercellular Communication	A lung biopsy was taken and revealed histologically: chronic non-specific inflammation in the pleuropulmonary border, intrapleural edema with eightfold pleural thickening in comparison to normal, angiogenesis in both the nutritive and functional intrapleural blood vessels, no abnormalities of lymphatic vessels with normal topographical distribution as detected by immunohistochemistry for antibody D2-40, granulomatous chronic foreign body reaction as a consequence of pleural effusion therapy by talcum pleurodesis.The histopathological findings of chronic non-specific pleuritis with angiogenesis and increased permeability of blood vessels led to massive intrapleural edema with pleural effusion.	22048329
Pregnancy Complications, Neoplastic, Communicable Diseases, Inflammation	Altered Intercellular Communication	Considering the features of this disease, they are probably secondary to chronic r infectious or immunological inflammation or paraneoplastic complications with angiogenesis (in about 19%).	22048329
Schizophrenia	Altered Intercellular Communication	Recent evidence suggests that schizophrenia may result from alterations of integration of signaling mediated by multiple neurotransmitter systems.	22048463
Inflammation, Carcinogenesis, Primary malignant neoplasm	Altered Intercellular Communication	Chronic oxidative stress and inflammation have been indicated as major mediators during carcinogenesis and cancer progression.	22048816
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	To explore the putative association of new-onset diabetes and the soluble urokinase plasminogen activator receptor (suPAR), which is a new and stable plasma marker of immune function and low-grade inflammation.	22050462
Inflammation, polyps, Colorectal Carcinoma	Altered Intercellular Communication	Important endoscopic diagnoses were defined as colorectal cancer (CRC), polyps, diverticuli and inflammation.	22050603
Finger joint structure, Inflammation	Altered Intercellular Communication	Sum scores evaluated by grayscale US showed that synovial inflammation in finger joints was detected significantly more frequently in the palmar aspect than on the dorsal side (p = 0.001).	22052070
Inflammation, Hypertension, CTCAE, Haiti	Altered Intercellular Communication	However, the influence of cardiovascular risk factors and inflammation on the urinary levels of this marker in hypertension (HT) has never evaluated.	22052073
Inflammation, Traumatic injury, Pain Distress Question	Altered Intercellular Communication	The diagnosis group displaying the highest injury prevalence was inflammation and pain in the gradual onset category (1-year prevalence, 20.9%; 95% CI, 16.2%-26.2%; and point prevalence, 23.2%; 95% CI, 18.4%-28.7%).	22053325
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Routine laboratory markers Alb, BPC and WBC were significantly correlated with hepatic histological inflammation grade and fibrosis stage.	22053373
Fitz-Hugh-Curtis syndrome, Chlamydia trachomatis, Inflammation, Pelvic Inflammatory Disease	Altered Intercellular Communication	Fitz-Hugh-Curtis syndrome is an inflammation of the liver capsule as a complication of pelvic inflammatory disease, whose etiologic agent is the most common C. trachomatis.	22054272
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	Type 2 diabetes mellitus and atherosclerosis are complex diseases sharing common antecedents like inflammation.	22055258
Inflammation, Atherosclerosis	Altered Intercellular Communication	CXCL16 is a chemokine involved in atherosclerosis by promoting inflammation, lipid accumulation and matrix degradation.	22055341
Fibrosis Assessment, Acute and chronic inflammation, Edema	Altered Intercellular Communication	Pancreatic duct size and index, fibrosis grade, fat content, edema, and signs of chronic and acute inflammation were measured in frozen sections of the resection margin and were then compared.	22056514
Granulomatous inflammation	Altered Intercellular Communication	Histopathological examination showed granulomatous inflammation in four patients.	22056858
Crohn Disease	Altered Intercellular Communication	The Lewis score (LS) and the Capsule Endoscopy Crohn's Disease Activity Index (CECDAI) have been developed to standardize the reporting of small-bowel inflammation.	22057284
Gastrointestinal inflammation	Altered Intercellular Communication	Fecal calprotectin (FC) represents a highly reliable biomarker of intestinal inflammation.	22057284
Inflammation, Cachexia	Altered Intercellular Communication	Inflammation in older persons is associated with frailty, cachexia, and disability.	22057579
Presenile dementia, Inflammation	Altered Intercellular Communication	Having eleven or more missing teeth seemed to be associated with a lower risk of dementia in people with lower education possibly owing to the suppression of source of chronic inflammation.	22059867
Inflammation	Altered Intercellular Communication	Interleukin (IL)-1b plays an important role in inflammation and has been associated with fibrotic remodelling.	22059992
vascular inflammations, Periodontitis, Atherosclerosis	Altered Intercellular Communication	It is suggested that periodontitis enhances the process of vascular inflammation leading to atherosclerosis.	22060049
Inflammation, physiopathological, Diabetes Mellitus, Non-Insulin-Dependent, Vascular Diseases	Altered Intercellular Communication	Adipose tissue dysfunction is associated with inflammation, type 2 diabetes mellitus and vascular diseases.	22064157
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	Tacrolimus (TAC) suppresses immune-inflammation by an intermediary inhibition of calcineurin activation in the treatment of rheumatoid arthritis (RA).	22065071
Inflammation, Ureteral obstruction, Hydronephrosis	Altered Intercellular Communication	(18)F-fluoro-2-deoxy-D: -glucose positron emission tomography (FDG-PET)/computed tomography (CT) clearly depicted an inflammation of the left peri-iliac arterial soft tissue, which was thought to be the cause of the ureteral obstruction and hydronephrosis.	22065104
Hydronephrosis, Arteritis	Altered Intercellular Communication	Our case shows that peri-iliac arterial inflammation occurs in GPA and causes hydronephrosis.	22065104
Inflammation, Traumatic injury, Corneal keloid	Altered Intercellular Communication	This report describes a very rare case of bilateral corneal keloid in the absence of trauma or inflammation that was diagnosed by histological and immunohistochemical examination and electron microscopy.	22067103
Exanthema, Stomatitis, Ulceration, CTCAE, Inflammatory disease of mucous membrane, Fatigue	Altered Intercellular Communication	Related adverse events were generally mild or moderate and consisted primarily of stomatitis, mucosal inflammation, mouth ulceration, rash, and fatigue.	22067397
Inflammation Mediators, Uveitis	Altered Intercellular Communication	To interrogate inflammation-mediated angiogenesis, we investigated experimental autoimmune uveoretinitis, an animal model for human uveitis.	22067906
Inflammation	Altered Intercellular Communication	Increased alveolar nitric oxide and systemic inflammation markers in silica-exposed workers.	22068172
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	High levels of fetuin-A has been linked to cardiovascular disease, possibly via modulating low-grade systemic inflammation.	22068809
Chemosis of conjunctiva, Inflammation, Ophthalmoplegia, Edema	Altered Intercellular Communication	Patients may present with preseptal inflammation, lid edema, chemosis, or ophthalmoplegia.	22070879
Inflammation, Primary malignant neoplasm, Infectious agent	Altered Intercellular Communication	Chronic inflammation associated with some infectious agents can lead to cancer.	22070917
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Vagal nerve activity may predict prognosis in cancer due to its roles in modulating inflammation, sympathetic activity and oxidative stress.	22070982
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Low-grade adipose tissue inflammation in patients with mild-to-moderate chronic obstructive pulmonary disease.	22071714
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Low-grade systemic inflammation is common in chronic obstructive pulmonary disease (COPD), but its source remains unclear.	22071714
ARCN1 gene, Inflammation, Hypoxia	Altered Intercellular Communication	Adipose tissue is a potent producer of inflammatory mediators and may contribute to systemic inflammation in COPD, possibly via hypoxia.	22071714
ARCN1 gene, Inflammation	Altered Intercellular Communication	We studied the influence of COPD and exercise-induced oxygen desaturation on adipose tissue inflammation (ATI) and its contribution to systemic inflammation.	22071714
ARCN1 gene, Inflammation	Altered Intercellular Communication	In COPD patients, mild-to-moderate COPD, per se, does not enhance ATI or its contribution to systemic inflammation compared with in well-matched healthy control subjects.	22071714
Refractory anemias, Inflammation	Altered Intercellular Communication	Construct validity and reliability of ultrasound disease activity score in assessing joint inflammation in RA: comparison with DAS-28.	22072084
Refractory anemias, Arthritis	Altered Intercellular Communication	To investigate the construct validity and reliability of US DAS compared with 28-joint DAS (DAS-28) in assessing joint inflammation and in prediction of structural damage in patients with RA.	22072084
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	A diagnosis of malignancy in the ampulla was only made after several ERCP attempts due to residual inflammation at the periampullary area.	22072249
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Low-grade inflammation and increased immunity related to cardiovascular diseases have been described in children and adults, however, studies in Mexican adolescents are being done at present.	22072361
Hyperammonemia, Inflammation, Impaired cognition	Altered Intercellular Communication	To assess the contribution of hyperammonemia and inflammation to induction of mild cognitive impairment (or MHE).	22072427
Nonalcoholic Steatohepatitis, Inflammation, Psoriasis, Hyperammonemia, Non-alcoholic Fatty Liver Disease, Liver Cirrhosis, Fatty Liver Disease	Altered Intercellular Communication	The study included patients with 1) liver cirrhosis, showing hyperammonemia and inflammation; 2) non-alcoholic fatty liver disease (NAFLD) showing inflammation but not hyperammonemia; 3) non-alcoholic steatohepatitis (NASH) showing inflammation and very mild hyperammonemia; 4) psoriasis, showing inflammation but not hyperammonemia; 5) keloids, showing both inflammation and hyperammonemia and 6) controls without inflammation or hyperammonemia.	22072427
Inflammation, Impaired cognition, Liver diseases, Hyperammonemia, Liver Cirrhosis	Altered Intercellular Communication	The data reported show that in patients with liver diseases, cognitive impairment may appear before progression to cirrhosis if hyperammonemia and inflammation are high enough.	22072427
Inflammation, Impaired cognition, Hyperammonemia, Liver Cirrhosis, Fatty Liver Disease	Altered Intercellular Communication	Five out of 11 patients with NASH, without liver cirrhosis, showed cognitive impairment associated with hyperammonemia and inflammation.	22072427
Hyperammonemia, Inflammation, Hepatobiliary Disorder, Impaired cognition	Altered Intercellular Communication	Patients with keloids showed cognitive impairment associated with hyperammonemia and inflammation, in the absence of liver disease.	22072427
Hyperammonemia, Inflammation, Hepatobiliary Disorder	Altered Intercellular Communication	Hyperammonemia or inflammation alone did not induce CI but the combination of certain levels of hyperammonemia and inflammation is enough to induce CI, even without liver disease.	22072427
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Circulating C-reactive protein (CRP), reflective of systemic chronic low-grade inflammation, is a marker associated with cardiovascular disease (CVD).	22072642
Inflammation	Altered Intercellular Communication	One of the mechanisms through which physical activity might promote cardiovascular health is by preventing changes in inflammation biomarkers, such as CRP.	22072642
Neurogenic Inflammation, Dental Plaque	Altered Intercellular Communication	The increased plaque and neuronal inflammation were accompanied by the generation of N(e)-carboxymethyl lysine in advanced glycation end products, a rapid marker of oxidative damage, induced by Sod1 gene-dependent reduction.	22072713
Gingivitis, Demographics Domain	Altered Intercellular Communication	DM subjects with a low educational background, having higher HbA1c% and males are more likely to experience gingival inflammation.	22073462
Pain Distress Question, Inflammation	Altered Intercellular Communication	Genetic factors play a role in the etiology of persistent pain conditions, putatively by modulating underlying processes such as nociceptive sensitivity, psychological well-being, inflammation, and autonomic response.	22074755
Synovitis, Inflammation, Rheumatoid Arthritis, Edema of bone marrow	Altered Intercellular Communication	Correlation between computer-aided dynamic gadolinium-enhanced MRI assessment of inflammation and semi-quantitative synovitis and bone marrow oedema scores of the wrist in patients with rheumatoid arthritis--a cohort study.	22075065
Refractory anemias, Inflammation, Synovitis, Edema of bone marrow	Altered Intercellular Communication	To test the correlation between assessment of inflammation using dynamic contrast-enhanced MRI (DCE-MRI) analysed by a novel computer-aided approach and semi-quantitative scores of synovitis and bone marrow oedema (BME) using the OMERACT-RA MRI Scoring (RAMRIS) system, in the wrist of patients with RA.	22075065
Inflammation	Altered Intercellular Communication	This technique may be useful for quick semi-automated assessment of joint inflammation, but needs further validation.	22075065
Inflammation, Myositis	Altered Intercellular Communication	The inflammatory myopathies (IMs) are a group of disorders characterised by weakness and inflammation of the skeletal muscles.	22075187
Chronic inflammation, Rheumatoid Arthritis, Crohn Disease, Inflammatory Breast Carcinoma, Disease	Altered Intercellular Communication	Transsignaling of interleukin (IL)-6 is a central pathway in the pathogenesis of disorders associated with chronic inflammation, such as Crohn disease, rheumatoid arthritis, and inflammatory colon cancer.	22075248
22q11.2	Altered Intercellular Communication	[Growth hormone deficiency associated with 22q11.2 deletion: a case report].	22075807
Hypoplasia of the pituitary gland, DiGeorge Syndrome, hormone deficiency, teratologic	Altered Intercellular Communication	We found growth hormone deficiency and pituitary hypoplasia associated with some of the anomalies shown above, thus we suspected and confirmed the 22q11.2 deletion syndrome.	22075807
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Neutrophilic airway inflammation is one of the key features of chronic obstructive pulmonary disease (COPD).	22076427
Inflammation	Altered Intercellular Communication	The chemokine receptors 1 (CXCR1) and 2 (CXCR2) are expressed in the bronchial mucosa during chronic inflammation and might be of importance for transepithelial migration of neutrophils.	22076427
Inflammation, Obesity	Altered Intercellular Communication	The results indicate that the two kinds of protein can modestly improve serum lipids and markers associated with obesity and inflammation.	22077928
Inflammation, Arthritis	Altered Intercellular Communication	Adiponectin is an adipokine that regulates energy metabolism and insulin sensitivity, but recent studies have pointed also to a role in inflammation and arthritis.	22077999
Cartilage destruction, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	The purpose of the present study was to investigate the association and effects of adiponectin on inflammation and cartilage destruction in osteoarthritis (OA).	22077999
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Lipoprotein(a) and inflammation in patients with atrial fibrillation after electrical cardioversion.	22078666
Pain Distress Question, Inflammation	Altered Intercellular Communication	Substance P (SP) and calcitonin gene-related peptide (CGRP) are released by the nociceptive sensory nerve and are involved in blood flow, pain and inflammation in the nasal mucosa.	22079125
Inflammation, Thrombosis, Peripheral Arterial Diseases, Cerebrovascular accident, Cerebrovascular Disorders, Hypertension, CTCAE	Altered Intercellular Communication	MPV is now considered a link between inflammation and thrombosis in multiple cardiovascular and cerebrovascular disorders including hypertension, peripheral artery disease, and stroke.	22079338
Airway structure, Asthma	Altered Intercellular Communication	The role of low-level lactate production in airway inflammation in asthma.	22080752
Inflammation, Asthma	Altered Intercellular Communication	The objective was to study aerobic glycolysis in human asthma and the role of this metabolic pathway in airway hyperreactivity and inflammation in a mouse model of asthma.	22080752
Airway structure, Asthma, Hyperreactivity	Altered Intercellular Communication	DCA also inhibited airway inflammation and hyperreactivity in a mouse model of asthma.	22080752
Bacteremia, Communicable Diseases, Inflammation	Altered Intercellular Communication	Significant improvements from H-Surg to H-IR catheters include the reduction in exit-site inflammation and infection (27.8% to 5.4%) and in bacteremic episodes (72.2% to 27.0%).	22080756
Inflammation, Granulation finding	Altered Intercellular Communication	Pathologic review showed non-necrotizing granulomatous inflammation with granulation tissue.	22082596
Inflammation, Atherosclerosis, Hyperglycemia, Obesity, Hypertension, CTCAE	Altered Intercellular Communication	High-sensitivity C-reactive protein (hs-CRP) is a marker for low-grade inflammation, as well as atherosclerosis, obesity, hyperglycemia and hypertension.	22082888
Phlebitis, Retractile Mesenteritis	Altered Intercellular Communication	Sclerosing mesenteritis is a rare, benign disorder characterized by non-specific and chronic inflammation of the mesenteric adipose tissue.	22082901
Hypercalcemia, CTCAE	Altered Intercellular Communication	[Hypercalcemia associated with parathyroid hormone-related protein(PTHrP)in a patient with diffuse large- type B-cell lymphoma(DLBCL)].	22083203
Inflammation, Squamous cell carcinoma	Altered Intercellular Communication	The importance of stromal inflammation in squamous cell carcinoma of the tongue.	22084865
Burn Specimen Source Codes, Pneumonitis	Altered Intercellular Communication	Pulmonary levels of suPAR are elevated in burn patients with inhalation trauma, and they correlate with pulmonary inflammation and coagulation.	22085408
Inflammation, Organ Dysfunction Scores, Critical Illness	Altered Intercellular Communication	We analyzed serum HA levels in 164 critically ill patients at a medical ICU and 61 healthy controls, with respect to organ dysfunction, systemic inflammation and mortality.	22085533
Inflammation, Atherosclerosis	Altered Intercellular Communication	Ageing is an important determinant of atherosclerosis development rate, mainly by the creation of a chronic low-grade inflammation.	22085595
Celiac Disease, Inflammation	Altered Intercellular Communication	Duodenum biopsy demonstrated short villi, chronic inflammation and an increase in the number of intraepithelial lymphocytes, all these was consistent with celiac disease Marsh 3.	22086322
Cardiovascular Diseases, Presenile dementia, Cerebrovascular accident, Vasculitis, Hypertension, CTCAE	Altered Intercellular Communication	Hypertension, a key risk factor for stroke, cardiovascular disease and dementia, is associated with chronic vascular inflammation, and although poorly understood, putative mechanisms include pro-inflammatory responses induced by mechanical stretching, with cytokine release and associated up-regulated expression of adhesion molecules.	22086659
Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn, Peritonitis	Altered Intercellular Communication	Acute respiratory distress syndrome (ARDS) occasionally occurs after gastrointestinal surgery involving severe inflammation such as diffuse peritonitis.	22086692
hearing impairment, Inflammation	Altered Intercellular Communication	Age-related hearing loss is a common disabling condition but its causes are not well understood and the role of inflammation as an influencing factor has received little consideration in the literature.	22086966
Granulomatous inflammation	Altered Intercellular Communication	The diagnosis may be problematic since the known causes of granulomatous inflammation must be excluded.	22087521
Inflammation, COL4A2 wt Allele	Altered Intercellular Communication	The role of inflammation in the pathophysiology of ICH is increasingly recognized.	22087759
Inflammation	Altered Intercellular Communication	These associations might be attributed to the chronic inflammation induced by excess adiposity.	22088365
Inflammation	Altered Intercellular Communication	A call for observations of such cases was sent to members of the French "Club rhumatismes et inflammation".	22088934
ARCN1 gene, Inflammation	Altered Intercellular Communication	Effect of fruit and vegetable intake on oxidative stress and inflammation in COPD: a randomised controlled trial.	22088966
ARCN1 gene, Inflammation	Altered Intercellular Communication	Increasing FV intake may attenuate the oxidative stress and inflammation associated with COPD.	22088966
ARCN1 gene, Inflammation	Altered Intercellular Communication	An exploratory randomised controlled trial to examine the effect of increased consumption of FV on oxidative stress and inflammation in moderate-to-severe COPD was conducted.	22088966
Airway structure, Inflammation	Altered Intercellular Communication	There were no significant changes in biomarkers of airway inflammation (interleukin-8 and myeloperoxidase) and systemic inflammation (C-reactive protein) or airway and systemic oxidative stress (8-isoprostane).	22088966
Inflammation, Dryness (characteristic), Irritation	Altered Intercellular Communication	Elevation in MUC1 and MUC16 mRNA and/or protein levels in postmenopausal women with non-Sjogren dry eye with a history of dry eye may be a compensatory response to irritation and inflammation associated with the disease.	22089171
Inflammation, Traumatic injury	Altered Intercellular Communication	Indices of systemic inflammation in this human inflammation model were compared with those of 12 trauma patients with a mean injury severity score of 19.	22089204
Inflammation, Endotoxemia, Traumatic injury	Altered Intercellular Communication	Neutrophil activation was present 3 h after onset of inflammation, both during experimental endotoxemia as well as in trauma patients.	22089204
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation is a distinctive pattern of chronic inflammatory reaction characterized by accumulation of epithelioid histiocytes and multinucleate giant cells.	22089785
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	Assessment of valvular calcification and inflammation by positron emission tomography in patients with aortic stenosis.	22090163
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	The pathophysiology of aortic stenosis is incompletely understood, and the relative contributions of valvular calcification and inflammation to disease progression are unknown.	22090163
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	Positron emission tomography is a novel, feasible, and repeatable approach to the evaluation of valvular calcification and inflammation in patients with aortic stenosis.	22090163
Inflammation, Atrial Fibrillation by ECG Finding, osteoclast activating factor, Postpericardiotomy Syndrome, Pericarditis, CTCAE	Altered Intercellular Communication	Inflammation and pericarditis may be contributing factors for postoperative atrial fibrillation (POAF), and both are potentially affected by antiinflammatory drugs and colchicine, which has been shown to be safe and efficacious for the prevention of pericarditis and the postpericardiotomy syndrome (PPS).	22090167
Inflammation, Graves Disease	Altered Intercellular Communication	Metallothioneins (MT) are small proteins induced by tissue stress that can contribute to restoring homeostasis of tissue inflammation and have been found to be increased in a transcriptomic analysis of Graves' disease (GD) glands.	22090273
Inflammation, Sinusitis, Meningitis	Altered Intercellular Communication	Ongoing inflammation in maxillary sinuses detected in brain MRI suggested that meningitis could be related to previous sinus infection.	22090306
Delirium, Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	In addition, frailty and delirium may have shared pathophysiology, such as inflammation, atherosclerosis, and chronic nutritional deficiencies, which will require further investigation.	22091571
Inflammation, Osteopenia, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Compared with patients with no significant stenosis, poor periodontal health including missing teeth, periodontal inflammation, and bone loss is associated with angiographically verified coronary artery narrowing in patients with stable CAD or ACS.	22092472
Inflammation	Altered Intercellular Communication	Bone loss was associated with complex multiple coronary lesions, beyond systemic inflammation.	22092604
Inflammation	Altered Intercellular Communication	An increase in cytokines at 48 h after the challenge was demonstrated and might, with further studies, give us a better understanding of the nature of inflammation in AKC.	22092652
Inflammation	Altered Intercellular Communication	Inflammation and oxidative stress are lower in physically fit and active adults.	22092747
Inflammation	Altered Intercellular Communication	These data indicate that an inverse relationship exists among chronic inflammation, oxidative stress, and pFIT and ExFreq at the community level even after adjustment for important confounders.	22092747
Inflammation, Psoriasis	Altered Intercellular Communication	Psoriasis is characterized by lower stratum corneum (SC) hydration and dermal inflammation.	22092918
Pain Distress Question, Inflammation	Altered Intercellular Communication	Statistically significant factors influencing this potential choice were number of episodes of pain (P=0.006, OR=1.23, 95% CI: 1.060-1.430) and number of attacks of inflammation (P=0.048, OR=1.27, 95% CI: 1.002-1.598).	22093049
Inflammation, Fibrosis Assessment, Calcinosis	Altered Intercellular Communication	Histopathology of pericardial specimens was reviewed and evaluated semiquantitatively on a 4-point scale for the extent of calcification, fibrosis, inflammation, and neovascularization.	22093269
Inflammation, Granulation finding	Altered Intercellular Communication	The DHE+ group had greater fibroblastic proliferation and neovascularization, as well as more prominent chronic inflammation and granulation tissue.	22093269
Inflammation	Altered Intercellular Communication	Fibroblastic proliferation and chronic inflammation correlated with DHE presence quantitated by DHE score (Spearman r = 0.578, p < 0.002, and r = 0.590, p < 0.002, respectively), but not with pericardial thickness.	22093269
Coronary Artery Disease	Altered Intercellular Communication	Prevalence and risk factors of carotid vessel wall inflammation in coronary artery disease patients: FDG-PET and CT imaging study.	22093271
Inflammation	Altered Intercellular Communication	Carotid inflammation was quantified in 82 CAD patients (age 62 +- 10 years) as the maximum target-to-background ratio ((wholevessel)TBR(max)).	22093271
Inflammation, Hypertension, CTCAE, Obesity	Altered Intercellular Communication	Carotid inflammation as revealed by FDG-PET is highly prevalent in the CAD population and is associated with obesity, age over 65 years, history of hypertension, smoking, and male gender.	22093271
helium, Hepatic Encephalopathy, Gastrointestinal inflammation, Bacterial peritonitis	Altered Intercellular Communication	Bacterial translocation, causing intestinal inflammation, is one of the key mechanisms in the pathogenesis of hepatic encephalopathy (HE) and spontaneous bacterial peritonitis (SBP) The presence of fecal calprotectin quantitatively relates to intestinal neutrophil migration and is therefore considered as a marker of intestinal inflammation.	22093455
Cirrhotic	Altered Intercellular Communication	FCCs were higher in cirrhotic subjects with additional extra-intestinal inflammation (P<0.01; sensitivity=0.65, specificity=0.8).	22093455
Inflammation, Cirrhotic	Altered Intercellular Communication	The Pearsons correlation coefficients were 0.190 and 0.164 revealing no influence (P=0.142 and P=0.207) of laboratory parameters of systemic inflammation on FCCs in cirrhotic subgroup.	22093455
Inflammation	Altered Intercellular Communication	In case of subcutaneous and intramuscular injection of metallic mercury we recommend marginal or wide excision of all contaminated tissue to prevent migration of mercury and chronic inflammation.	22093686
Primary sclerosing cholangitis, Gastrointestinal inflammation, Inflammatory Bowel Diseases	Altered Intercellular Communication	The relationship between site of intestinal inflammation and primary sclerosing cholangitis (PSC) development in inflammatory bowel disease (IBD) has not been studied extensively, but may be important in understanding the pathogenesis of PSC.	22094024
Inflammation	Altered Intercellular Communication	A higher release of polyethylene and metal particles is triggered, which leads to a slow but continuous process of inflammation.	22094154
Cough variant asthma, Inflammation, Coughing, Cerebrovascular accident, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	Cough variant asthma (CVA) is a phenotype of asthma presenting solely with coughing, characterized by airway hyperresponsiveness, eosinophilic inflammation and a cough response to bronchodilators.	22094623
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	The antitussive effect of montelukast in CVA may be attributed to the attenuation of eosinophilic inflammation rather than its bronchodilatory properties.	22094623
deficiency aspects	Altered Intercellular Communication	Hormonal deficiency may partially account for this finding.	22094737
Airway structure	Altered Intercellular Communication	However, the mode of the underlying chronic airway inflammation is different.	22094827
Deposition, Interstitial inflammation	Altered Intercellular Communication	We also correlated the presence/absence of interstitial inflammation and IgG subclasses in the TBM and vascular deposits.	22095887
Interstitial inflammation	Altered Intercellular Communication	Interstitial inflammation did not correlate with the presence of IgG staining or distribution of IgG subclasses in the TBM.	22095887
Interstitial inflammation	Altered Intercellular Communication	Interstitial inflammation was more common in biopsies of African-American patients than Caucasian patients.	22095887
Tubulitis Assessment, Interstitial inflammation, Glomerulitis (disorder)	Altered Intercellular Communication	Two pathologists, blinded to clinical data, reviewed biopsies from 30 patients according to a standardized protocol that included assessment of T cell, B cell, and plasma cell infiltration, as well as scoring for tubulitis, interstitial inflammation, and glomerulitis.	22095945
Inflammation, renal anemia	Altered Intercellular Communication	This study sought to determine whether high-flux dialysis would help improve markers of renal anemia, inflammation, and oxidative stress compared with low-flux dialysis.	22096040
Inflammation	Altered Intercellular Communication	Markers of inflammation, oxidative stress, or nutritional status also did not differ between groups.	22096040
Inflammation	Altered Intercellular Communication	Chronic inflammation, as reflected by increased level of acute phase protein such as C-reactive Protein (CRP) is highly prevalent in hemodialysis patients.	22097096
Inflammation	Altered Intercellular Communication	Our study provides further support for a role of inflammation in the pathophysiology of suicidality.	22098148
Inflammation, Fibrosis Assessment, Lesion of liver, Fatty Liver Disease	Altered Intercellular Communication	In morbid obese patients, NASH, particularly lobular inflammation and advanced fibrosis, associates with mild decreases in eGFR, suggesting a common inflammatory link between liver and renal lesion.	22098270
Inflammation, Destruction of tissue	Altered Intercellular Communication	In addition, the frequent poor tooth conservation and gingival inflammation tend to amplify tissue destruction and symptoms and may impair and confuse the correct diagnosis, thus delaying the onset of specific treatment.	22098533
High Density Lipoproteins, Inflammation, Nerve Degeneration	Altered Intercellular Communication	CSF showed signs of neurodegeneration without inflammation, and autopsy verified HDLS in Case 1.	22098561
Inflammation, Chronic liver disease	Altered Intercellular Communication	Inflammation is a major factor for the progression of chronic liver diseases.	22098627
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	Interactions between urokinase plasminogen activator (uPA) and its receptor (uPAR) have been functionally linked to hepatic inflammation and fibrosis in mice.	22098627
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Circulating suPAR closely correlated with liver function, fibrosis markers, but also with systemic inflammation and renal function.	22098627
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	In additional models adjustments were performed for the single components constituting the metabolic syndrome and for inflammation.	22098712
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	These relations were not influenced by the individual components of metabolic syndrome or by inflammation.	22098712
Prostate carcinoma, prostatitis	Altered Intercellular Communication	More evidence indicate that prostate inflammation can lead to prostate cancer development.	22098728
Urinary tract infection, prostatitis	Altered Intercellular Communication	Ciprofloxacin is an antibacterial agent used mainly in urinary tract infections and prostate inflammation.	22098728
Primary malignant neoplasm, prostatitis	Altered Intercellular Communication	Firstly, ciprofloxacin can stop the acute and chronic prostate inflammation which can lead to cancer development.	22098728
Gingivitis	Altered Intercellular Communication	A 18-year-old girl with gingival inflammation particularly in the maxillary insicor area was referred to the authors' department.	22099313
Inflammation, Inflammatory disorder	Altered Intercellular Communication	In addition, macrophage migration inhibitory factor (MIF) is a key upstream regulator of inflammation, and it is a significant regulator of inflammatory diseases.	22099602
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	Our findings provide additional evidence for the relation between systemic inflammation and AF.	22100030
Inflammation, Atherosclerosis	Altered Intercellular Communication	The interplay between oxidative stress and inflammation is crucial in the pathogenesis of atherosclerosis.	22100252
Inflammation	Altered Intercellular Communication	Inflammation may play an essential role in the decline of physical performance.	22100319
Inflammation, Congenital Heart Defects	Altered Intercellular Communication	Patients presenting with cardiac abnormalities and evidence of systemic inflammation should be screened for Wegener's by history, radiographic and laboratory assessment.	22100479
Inflammation, Data types - Address	Altered Intercellular Communication	Specifically, three hypotheses may explain the role of GSTO1-1 in the pathophysiology of AD: the antioxidant activity of GSTO1-1 may protect brain tissue against oxidative stress; GSTO1-1 activity regulate interleukin-1b activation and its genetic variation may act to modulate inflammation in AD; GSTO1-1 is involved in the arsenic biotransformation pathway and gene polymorphisms may be implicated in the modulation of arsenic neurotoxicity.	22100662
Autoimmune Diseases, Inflammation, "Sjogrens Syndrome	Altered Intercellular Communication	Decreased salivary sulphotransferase activity correlated with inflammation and autoimmunity parameters in Sjogren's syndrome patients.	22101162
Inflammation, Carcinogenesis	Altered Intercellular Communication	The mast cells participate in inflammation and possibly in carcinogenesis.	22102069
Cardiovascular system	Altered Intercellular Communication	It is not known whether state-level variation in cardiovascular inflammation exists or could be explained by traditional clinical risk factors and behavioral lifestyle factors.	22102899
Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Although there was less inflammation (p = 0.038) and fibrosis (p = 0.029), non-alcoholic steatohepatitis and fibrosis were present in 61% and 55% of the Lean-NAFLD group, respectively.	22103042
Inflammation, Non-alcoholic Fatty Liver Disease, Metabolic Syndrome X	Altered Intercellular Communication	Fish oil improves lipid metabolism and ameliorates inflammation in patients with metabolic syndrome: impact of nonalcoholic fatty liver disease.	22103753
Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Hepatitis, Liver Cirrhosis	Altered Intercellular Communication	NAFLD can lead to liver inflammation, fibrosis and cirrhosis.	22103753
Inflammation, Heart failure, Pathology	Altered Intercellular Communication	We analyzed in parallel the proteomic profile of subjects with cardiac heart failure to discriminate these two pathologies, which show similar pattern of systemic inflammation process.	22104004
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide has been promoted as a non-invasive measure of airway inflammation, with clinical utility for the diagnosis and management of asthma.	22104032
Airway structure	Altered Intercellular Communication	Airway inflammation as measured by exhaled nitric oxide in young New Zealand children is related to their level of specific IgE to aeroallergens.	22104032
Inflammation	Altered Intercellular Communication	Our results demonstrate that IGFBP-1 mRNA and protein is detected at increased levels in human carotid plaques, possibly as a consequence of plaque inflammation.	22104117
Inflammation	Altered Intercellular Communication	Patients with HF-REF or HF-PEF presenting similar symptoms and functional limitations exhibit similar concentrations of biomarkers of ECM and inflammation.	22104539
Pyelonephritis, Xanthogranulomatous, Pyelonephritis, Tuberculosis, Secondary malignant neoplasm of kidney, Renal abscess, Renal Cell Carcinoma Pathway	Altered Intercellular Communication	Focal xanthogranulomatous pyelonephritis (XGP) is a chronic inflammatory condition that can mimic other disease conditions such as pyelonephritis, tuberculosis, renal abscess, renal cell carcinoma, and renal metastasis.	22105452
Eosinophilic disorder	Altered Intercellular Communication	Kimura disease is an uncommon chronic inflammatory condition of unknown etiology and is characterized by painless subcutaneous nodules, usually affecting the head and neck, eosinophilia, and markedly elevated immunoglobulin E levels.	22106083
Inflammation	Altered Intercellular Communication	ANCA specific to several antigens may worsen inflammation by reducing antimicrobial capacity of neutrophil proteases and cationic proteins.	22107137
Gastrointestinal inflammation	Altered Intercellular Communication	Calprotectin is a calcium- and zinc-binding protein and a marker in faeces of gastrointestinal inflammation.	22108340
Inflammation	Altered Intercellular Communication	HIV-infected children older than 4 years had a median FC concentration above the reference value, and gut inflammation in the children with elevated values is likely.	22108340
Peripheral ulcerative keratitis, Keratitis	Altered Intercellular Communication	Peripheral ulcerative keratitis is a destructive process involving perilimbal corneal inflammation and an overlying epithelial defect.	22108363
Thrombus, Inflammation, Edema	Altered Intercellular Communication	Antithromboembolic stockings can help eliminate edema of the legs in MS patients, and may also reduce the thrombotic risk: the lower d-Dimer values suggest an effect on the activation of inflammation and coagulation resulting from stasis-induced endothelial damage.	22108480
Inflammation, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	Those proteins may be associated with oxidative stress, mitochondrial dysfunction, abnormal protein aggregation and inflammation.	22108571
Entity Risk - Corrosive, Inflammation, Esophageal reflux observation, Fibrosis Assessment, congenital stenosis, Stenosis, Esophageal Achalasia, Post-Traumatic Stress Disorder, Ulcer of esophagus	Altered Intercellular Communication	The strictures had a range of causes: postoperative anastomotic stricture, corrosive stricture, postradiation stricture, esophageal achalasia, esophageal reflux, congenital stricture, esophageal web, esophageal ulcer, medication fibrosis, chronic inflammation, and posttraumatic stricture (in descending order of frequency).	22109306
vascular inflammations	Altered Intercellular Communication	(18)F-Fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT has the potential to track vascular inflammation and monitor therapeutic response.	22109668
Arteritis	Altered Intercellular Communication	The medium dose of atorvastatin over a 12-week period resulted in a significant reduction of arterial inflammation as well as various circulating biomarkers.	22109668
Inflammation	Altered Intercellular Communication	Chronic low-grade inflammation and adipokines dysregulation are linked to mechanisms underscoring the pathogenesis of obesity-related metabolic disorders.	22110665
Secondary malignant neoplasm of lung, Amenorrhea, Aggressive course, Bothered by Vomiting, Phenotypic abnormality, Anemia, Nausea	Altered Intercellular Communication	Our case report suggest that PGC is a highly aggressive tumor that is often associated with liver and lungs metastasis without evidence of pelvic organ abnormality and is associated with some hormonal effects, such as amenorrhea, anemia, nausea and vomiting mimicking pregnancy in young adult female	22111476
Inflammation, Northeast, HIV Infections	Altered Intercellular Communication	The role of vaccination against HSV-2 in near future and elimination of HSV-2 viral shedding along with genital tract inflammation in high HIV/HSV-2 areas may be an option for initiating successful intervention strategies to reduce the transmission and acquisition of HIV infection in Northeast India.	22111810
Osteomyelitis, Inflammation	Altered Intercellular Communication	Fluorodeoxyglucose positron-emission tomography-computed tomography (FDG-PET-CT) revealed severe inflammation of the CVC wall and a picture consistent with osteomyelitis and severe destruction of the body of the 11th thoracic vertebra.	22111828
Inflammation, Osteoporosis	Altered Intercellular Communication	However, no direct association could be revealed between lower bone density and markers of inflammation or inflammatory cytokines, except of IL-6 witch was significantly higher in AS patients with osteoporosis/osteopenia than those without.	22112431
Inflammation, Osteopenia	Altered Intercellular Communication	Inflammation might contribute to the accelerated bone loss in AS through stimulation of bone degradation.	22112431
atherosclerotic	Altered Intercellular Communication	Altered expression of inflammation-related genes in human carotid atherosclerotic plaques.	22112851
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is a pivotal process in atherosclerosis development and progression, but the underlying molecular mechanisms remain largely obscure.	22112851
Tumor necrosis	Altered Intercellular Communication	The positive association of tumor necrosis factor-a and nuclear factor-kB might be involved in the potential anti-inflammation mechanism of fish oil.	22113064
Inflammation, Stomach Carcinoma, Infection caused by Helicobacter pylori, Herpes	Altered Intercellular Communication	The development of gastric cancer (GC) is closely related to chronic inflammation caused by Helicobacter pylori infection, and herpes virus entry mediator (HVEM) is a receptor expressed on the surface of leukocytes that mediates potent inflammatory responses in animal models.	22113134
Inflammation, Rheumatoid Factor, Anemia	Altered Intercellular Communication	Exams revealed mild anemia, elevation of the biological parameters of inflammation and aminotransferases, positive cryoglobulin and rheumatoid factor in serum, and a severe reduction in C4 complement fraction.	22113605
Product Withdrawals, Inflammation, Gastrointestinal symptom	Altered Intercellular Communication	Moderate gluten doses also triggered mucosal inflammation and more gastrointestinal symptoms leading to premature withdrawals in seven cases.	22115041
Inflammation, Corneal edema	Altered Intercellular Communication	Graft rejection was defined as findings of keratic precipitates with or without corneal edema, or anterior chamber cell and flare with or without corneal edema after the initial resolution of perioperative inflammation.	22115709
Lymphatic Invasion Assessment, Inflammation, Neoplasms	Altered Intercellular Communication	The corresponding pathology slides showed only 1 of the 12 patients had dermal lymphatic invasion, whereas the other 11 specimens showed peritumoral inflammation without evidence of tumor invasion.	22116117
Lymphatic Invasion Assessment, Inflammation	Altered Intercellular Communication	This study demonstrates that the linear areas of reticulation are most commonly caused by peritumoral inflammation and are not due to dermal lymphatic invasion.	22116117
Inflammation, Vitreous Hemorrhage, Retinal Detachment, Injury of lens, Endophthalmitis, CTCAE	Altered Intercellular Communication	No cases had marked inflammation, lens injuries, marked vitreous hemorrhage, retinal detachment, or endophthalmitis.	22116499
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	There were 29 lesions of different final diagnosis, including 17 recurrence rectal cancers, 4 fibrous masses, 6 stoma inflammations, 1 sinus and 1 abscess.	22116720
Inflammation, Swelling, Hyperemia	Altered Intercellular Communication	At presentation, mild anterior segment inflammation was observed, together with sheathing mainly of the veins as well as hyperemia and swelling of the optic disc in the fundus.	22117324
Retinal Vasculitis, Papilledema, Intraocular Lymphoma	Altered Intercellular Communication	Intraocular lymphoma may present with atypical findings of optic disk inflammation and retinal vasculitis.	22117324
Inflammation, Diabetic Retinopathy	Altered Intercellular Communication	Fundus examination showed no signs of inflammation, but both a narrowing of the retinal arterioles and non-active diabetic retinopathy were observed.	22117326
Inflammation, hepcidin	Altered Intercellular Communication	In conclusion, serum hepcidin levels are associated with iron status and microinflammation (defined as hsCRP < 15 mg/l, without clinical manifestation of inflammation) in maintenance haemodialysis patients.	22118000
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	Activity and inflammation were mostly moderate or severe, while intestinal metaplasia and atrophy were mostly absent at all three sites.	22118692
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	Atrophy and intestinal metaplasia are rare but activity and chronic inflammation are severe at the antrum, angulus and corpus in NG.	22118692
Fibrosis Assessment, Hepatic inflammation, Hepatitis B	Altered Intercellular Communication	Significant hepatic inflammation was found in 59.3% of these patients, and significant hepatic fibrosis was found in 62.1%, the latter being associated with hepatitis B e antigen status, ALT levels and serum HBV-DNA, but not with their age group or viral genotype.	22118698
Inflammation, Adverse Event Associated with Constitutional Symptoms, Musculoskeletal Pain, Anemia, Thrombocytosis	Altered Intercellular Communication	Compared with GCA patients with elevated markers of inflammation, a greater proportion of these patients had polymyalgia rheumatica symptoms (P = 0.008), whereas constitutional symptoms, anemia and thrombocytosis, were observed less often (P < 0.05).	22119103
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Vitamin A affects inflammation and immune function and is thus a factor of interest in relation to cardiovascular disease (CVD).	22119336
Parkinson Disease, Inflammation	Altered Intercellular Communication	Markers of inflammation in prevalent and incident Parkinson's disease in the Cardiovascular Health Study.	22119505
Parkinson Disease, Inflammation, palladium	Altered Intercellular Communication	Studies demonstrate existence of inflammation in prevalent Parkinson's disease (PD).	22119505
palladium, Inflammation	Altered Intercellular Communication	Although inflammation exists in PD, it may not represent an etiologic factor.	22119505
Inflammation	Altered Intercellular Communication	suPAR was significantly positively correlated with markers of systemic inflammation (i.e., high sensitive C-reactive protein (hsCRP) and white blood cells (WBC), but not to lipoprotein-associated phospholipase A2 (Lp-PLA(2)), a specific vascular inflammatory biomarker.87 subjects had a CVD event during follow-up (mean 14.1 years).	22119508
Inflammation, Intellectual Disability	Altered Intercellular Communication	Inflammation and oxidative stress as biomarkers of premature aging in persons with intellectual disability.	22119683
Inflammation, Intradermal Route of Drug Administration	Altered Intercellular Communication	Our hypothesis was that chronic inflammation in the bloodstream of persons with ID contributes to their "premature aging".	22119683
Inflammation, Intradermal Route of Drug Administration	Altered Intercellular Communication	Asymptomatic inflammation in the bloodstream of the older adults with ID might explain the "premature aging" of these individuals.	22119683
Primary CNS Vasculitis	Altered Intercellular Communication	Primary central nervous system vasculitis (PCNSV) is a rare and poorly described vascular inflammatory condition confined within the central nervous system (CNS).	22120304
Pancreatic Neoplasm, Inflammation	Altered Intercellular Communication	MHC class II expression in pancreatic tumors: a link to intratumoral inflammation.	22120497
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	The pathogenesis of coronary artery disease (CAD) is closely associated with inflammation, in which human leukocyte antigens (HLA), especially HLA-DR molecules, play important roles.	22122841
Refractory anemias, Inflammation	Altered Intercellular Communication	Overall, our findings suggest that CD4(+)CD28(-) T cells migrate in response to a chemotactic gradient of fractalkine to sites of inflammation, where they contribute to the inflammatory processes in a subgroup of patients with MS and RA.	22123179
Inflammation, Osseous metaplasia, Neoplasms, Skin, Osteoma cutis	Altered Intercellular Communication	Primary osteoma cutis arises in otherwise unaffected skin, often in patients with systemic conditions, whereas secondary osteoma cutis is associated with cutaneous neoplasms and inflammation (metaplastic ossification).	22123193
allergic inflammation	Altered Intercellular Communication	Insufficient Treg and Th1 cells may be associated with the allergic inflammation that may be attributed to the Th2 immune response in patients suffering from AR who are sensitive to olive pollen.	22123238
ARCN1 gene, Inflammation	Altered Intercellular Communication	Chronic inflammation plays an important role in both diseases: lung cancer and COPD.	22123552
Inflammation, Carcinoma of lung	Altered Intercellular Communication	However, it seems that inflammation is more pronounced in patients with lung cancer, as the CRP levels were significantly higher in these patients than other groups.	22123552
Orbital Pseudotumor	Altered Intercellular Communication	The differences of tear inflammatory cytokines between patients with active and inactive TAO indicated that orbital inflammation may be involved in the ocular surface damage of TAO.	22124787
Inflammation, Colorectal Carcinoma, Sinonasal Adenocarcinoma	Altered Intercellular Communication	Intestinal-type sinonasal adenocarcinoma (ITAC) is an epithelial cancer of the sinonasal sinuses that shows histological similarity to colorectal cancer (CRC) and share chronic inflammation as a possible etiological factor.	22125792
Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	Gingival inflammation index, plaque index, probing depth, periodontal attachment level (AL), and bleeding on probing were taken for each subject.	22126098
Inflammation	Altered Intercellular Communication	It occurs frequently in conditions characterized by immune activation and inflammation.	22126431
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Baseline NAS was associated with progressive disease in a univariate binary logistic regression analysis (p = 0.024), but no difference was seen in the multivariate analysis including the NAS, portal inflammation, and perisinusoidal fibrosis.	22126450
Communicable Diseases, Phlebitis of portal vein, Septic thrombophlebitis, Inflammation	Altered Intercellular Communication	Pylephlebitis is defined as septic thrombophlebitis of the portal venous system, usually secondary to infection or inflammation in the abdomen.	22126528
Intraventricular	Altered Intercellular Communication	Intraventricular inflammation may be one mechanism by which IVH exerts deleterious effects.	22126859
Inflammation, Refractory anemias, Rheumatoid Arthritis, Anemia, hepcidin	Altered Intercellular Communication	To explore the utility of the novel iron indices hepcidin, reticulocyte hemoglobin content (Ret-Hgb), and erythrocyte (red blood cell) hemoglobin content (RBC-Hgb) for detection of iron deficiency in rheumatoid arthritis (RA) patients with anemia and active inflammation and to compare these indices with conventional parameters of iron deficiency.	22127690
Inflammation, Anemia, idarubicin, Chronic disease	Altered Intercellular Communication	Forty patients were classified as having either iron deficiency anemia (IDA), anemia of chronic disease (ACD), their combination (IDA/ACD), or "other anemia" based on biochemical parameters for inflammation and iron deficiency.	22127690
Refractory anemias, Inflammation, hepcidin, Anemia	Altered Intercellular Communication	Serum hepcidin and, to a lesser extent, urine hepcidin, Ret-Hgb, and RBC-Hgb, are potential useful indicators for detecting iron deficiency in RA patients with anemia and active inflammation.	22127690
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Inflammation and autoantibody markers identify rheumatoid arthritis patients with enhanced clinical benefit following rituximab treatment.	22127691
Sample Size Calculation, vascular inflammations, Fibrosis Assessment, Connective Tissue Diseases	Altered Intercellular Communication	Systemic sclerosis (SSc) is a connective tissue disease characterized by vascular inflammation and fibrosis.	22127711
Barrett Esophagus, Inflammation, Acid reflux, Rough endoplasmic reticulum	Altered Intercellular Communication	Frequent gastroesophageal reflux (GER) causes chronic inflammation and damages esophageal mucosa, which can lead to Barrett's esophagus.	22128757
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Evidence suggests vitamin D deficiency, perturbed glucose homeostasis, and increased inflammation all play roles in the development of diabetes.	22129188
Tissue Congestion, Heart failure	Altered Intercellular Communication	We examined the hypothesis that renal congestion is responsible for the decline in renal function in patients with heart failure (HF) via tubulointerstitial inflammation.	22129502
Inflammation, Venous Engorgement	Altered Intercellular Communication	Venous congestion may contribute to HF-induced deterioration of renal function by augmenting oxidative stress-mediated inflammation in the tubulointerstitium.	22129502
Inflammation, Metabolic Syndrome X, Acute myocardial infarction, Thrombus, MS gene	Altered Intercellular Communication	Metabolic syndrome (MS) may lead to worsened left ventricular systolic function by causing recurrent thrombotic events and by aggravating systemic inflammation in the course of acute myocardial infarction.	22129921
Inflammation	Altered Intercellular Communication	A biopsy led to the diagnosis of non-specific inflammation.	22130730
Orbital Pseudotumor	Altered Intercellular Communication	This case shows that sudden periorbital hemorrhages can be a sign for idiopathic orbital inflammation.	22130730
Airway structure, Allergic asthma, Allergy - Charge Type Reason	Altered Intercellular Communication	Inhalant exposure reduction with TLA improves quality of life, airway inflammation and systemic allergy in patients with persistent atopic asthma.	22131290
Cytopenia, Dermatitis, Lupus Erythematosus, Systemic	Altered Intercellular Communication	These clinical associations with SNPs in the promoter and 3' UTR regions align with previously reported SLE-susceptibility SNPs in OPN and suggest potential roles for these variants in antibody-mediated cytopenias and skin inflammation in SLE.	22131818
Coma (genus), Inflammation, Phlegmon, Inflammatory Breast Carcinoma	Altered Intercellular Communication	Several hours of pressure on the right breast during a coma was the cause of inflammation which appeared to be phlegmon or inflammatory breast cancer.	22132625
Orbital Pseudotumor	Altered Intercellular Communication	Orbital inflammation: a rare association of common variable immunodeficiency.	22132851
Common Variable Immunodeficiency, Orbital Pseudotumor	Altered Intercellular Communication	We describe a unique case of a patient with CVID who developed orbital inflammation.	22132851
Abnormal ocular motility, Exophthalmos, Orbital Pseudotumor	Altered Intercellular Communication	The patient was successfully treated with a course of oral prednisolone which resulted in improvement of orbital inflammation, ocular movements and proptosis.	22132851
Common Variable Immunodeficiency, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	To our knowledge this is the first reported case of non-granulomatous orbital inflammation in association with CVID.	22132851
Inflammation, Exacerbation of asthma	Altered Intercellular Communication	Noninvasive testing of lung function and inflammation in pediatric patients with acute asthma exacerbations.	22133263
Inflammation, Exacerbation of asthma	Altered Intercellular Communication	There is limited information on performance rates for tests of lung function and inflammation in pediatric patients with acute asthma exacerbations.	22133263
Communicable Diseases, Inflammation	Altered Intercellular Communication	Higher CSF cytokine levels (IL-8, p = 0.003; TNF-a, p = 0.019) were associated with the infection, but systemic inflammation results were controversial.	22133280
Presenile dementia, Inflammation	Altered Intercellular Communication	It can be concluded that inflammation plays an important role in both types of dementia.	22133543
Refractory anemias, Inflammation	Altered Intercellular Communication	Multiple inflammatory pathways contribute to persistent chronic inflammation in RA.	22133625
Pneumonitis, Systemic Scleroderma	Altered Intercellular Communication	Latent pulmonary inflammation in patients with systemic sclerosis.	22133713
Pneumonitis	Altered Intercellular Communication	Induced sputum is a non-invasive method for studying pulmonary inflammation.	22133713
Pulmonary function tests, Pneumonitis, Systemic Scleroderma	Altered Intercellular Communication	To assess pulmonary inflammation by analysis of induced sputum specimens in patients with systemic sclerosis and lung involvement, and to determine whether there is a correlation with the pulmonary function alterations in these patients.	22133713
Pneumonitis, Systemic Scleroderma	Altered Intercellular Communication	Pulmonary inflammation was present in all patients with systemic sclerosis included in the study, regardless of the presence of documented signs of pulmonary involvement.	22133713
Presenile dementia, Inflammation	Altered Intercellular Communication	The findings indicate that chronic caregiving of those with dementia may result in increased inflammation and, thereby, possibly increased CVD risk.	22133914
Inflammation, Heart failure, Depression, CTCAE	Altered Intercellular Communication	Cognitive/affective and somatic/affective symptom dimensions of depression are associated with current and future inflammation in heart failure patients.	22134045
Inflammation, Heart failure, Bipolar Disorder	Altered Intercellular Communication	Little is known about whether cognitive/affective depressive symptoms or somatic/affective depressive symptoms are associated with inflammation in heart failure (HF), or that the relation is confounded with disease severity.	22134045
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Further studies are warranted to replicate these findings and to examine the association between depression dimensions, inflammation and prognosis in HF.	22134045
Inflammation, Uveal Effusion Syndrome	Altered Intercellular Communication	Due to the the presence of a nanophthalmic eye without any evidence of inflammation or malignant growth, the diagnosis uveal effusion syndrome could be made.	22134345
Inflammation, Androgenetic Alopecia	Altered Intercellular Communication	The role of inflammation and immunity in the pathogenesis of androgenetic alopecia.	22134564
Inflammation, Androgenetic Alopecia	Altered Intercellular Communication	Biopsies from men with androgenetic alopecia showed a similar pattern of inflammation and immunoreactant deposition.	22134564
Inflammation, Obesity, Metaphyseal irregularity	Altered Intercellular Communication	Obesity is associated with chronic low-grade inflammation, which contributes to systemic metabolic irregularities and obesity-linked metabolic disorders.	22134720
Inflammation, physiopathological	Altered Intercellular Communication	Orosomucoid (ORM), an acute phase reactant protein, was shown to be produced in response to metabolic and inflammatory signals in the adipose tissue of obese mice, which protects them from severe inflammation and subsequent metabolic dysfunction.	22134720
Inflammation	Altered Intercellular Communication	The close links of ORM and measures of adiposity, insulin resistance, and adipose tissue inflammation in humans reinforce previous experimental data and warrant further studies to explore a possible role of ORM in the pathogenesis of obesity-associated metabolic derangements.	22134720
Inflammation, physiopathological	Altered Intercellular Communication	Orosomucoid (ORM), an acute phase reactant protein, was shown to be produced in response to metabolic and inflammatory signals in the adipose tissue of obese mice, which protects them from severe inflammation and subsequent metabolic dysfunction.	22134720
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Consumption of antioxidant-rich foods may reduce the risk of stroke by inhibition of oxidative stress and inflammation.	22135074
Airway structure, Cystic Fibrosis	Altered Intercellular Communication	Bile acids in sputum and increased airway inflammation in patients with cystic fibrosis.	22135379
Airway structure	Altered Intercellular Communication	Aspiration of BA was associated with increased airway inflammation.	22135379
ARCN1 gene, Inflammation, Hypercapnia	Altered Intercellular Communication	Sleep-related hypoxemia and hypercapnia are well recognized in COPD and the development of systemic inflammation during sleep.	22135488
Inflammation, Weight decreased	Altered Intercellular Communication	Reduced chemerin expression and serum concentration may contribute to improved insulin sensitivity and subclinical inflammation beyond significant weight loss.	22136911
Inflammation, Neoplasms, Necrosis	Altered Intercellular Communication	Tumors grown in Se- mice were loosely packed and showed increased necrosis and inflammation as compared to those in Se and Se+ mice.	22137259
vascular inflammations	Altered Intercellular Communication	Association between sRAGE, esRAGE levels and vascular inflammation: analysis with (18)F-fluorodeoxyglucose positron emission tomography.	22137663
vascular inflammations	Altered Intercellular Communication	(18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) is a novel imaging technique for detecting vascular inflammation.	22137663
Inflammation, Vascular Diseases, Purpura, Agranulocytosis lab result, Vasculitis, CTCAE	Altered Intercellular Communication	Known side effects of cocaine-related levamisole ingestion have included agranulocytosis and a cutaneous acral purpura that is histopathologically characterized by a mixture of inflammation (vasculitis) and occlusion (vasculopathy).	22138808
Unknown (origin) (qualifier value), Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	It is usually associated with chronic interstitial inflammation and fibrosis but may occasionally be idiopathic.	22139352
Pain Distress Question, Inflammation	Altered Intercellular Communication	Only one patient with persistent back pain underwent surgery for stabilization of the spine after the improvement of inflammation.	22139720
Inflammation, Neoplasms, Crypt hyperplasia	Altered Intercellular Communication	Pathological conditions within the small bowel such as loss of villi, crypt hyperplasia, advanced neoplasia, or increased blood flow due to inflammation tissue could be successful visualized.	22139876
Inflammation	Altered Intercellular Communication	Lobular inflammation occurred in 20.8% of the livers and PT inflammation in 38.8%.	22139908
Inflammation, Heat-Shock Response	Altered Intercellular Communication	It is increasingly clear that some heat shock proteins (Hsps) play a role in inflammation.	22140545
Inflammation, HSPD1 wt Allele	Altered Intercellular Communication	Hsp60 induction by NFkB-p65 and its release by epithelial cells after oxidative stress can have a role in maintaining inflammation, e.g., by stimulating neutrophils activity.	22140545
ARCN1 gene, Inflammation, Cardiovascular Diseases, Chronic Obstructive Airway Disease, Inflammatory disorder	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is considered to be a systemic inflammatory disease, and systemic inflammation has been noted as a factor contributing to cardiovascular disease, which is one of the comorbidities associated with COPD.	22142478
Inflammation, Rheumatoid Vasculitis, Aortitis	Altered Intercellular Communication	Aortitis, inflammation of the aortic tissue, is most commonly caused by vasculitic rheumatic conditions, and less frequently infectious organisms.	22143340
Pain Distress Question, Inflammation	Altered Intercellular Communication	Analgesics and left-over antibiotics were used to ease pain and reduce inflammation.	22144453
Inflammation, Pathology	Altered Intercellular Communication	A central role of A2A and A3 adenosine receptors (ARs) in mechanisms of inflammation has been reported in different pathologies.	22146575
Arthritis	Altered Intercellular Communication	A2A and A3AR density inversely correlated with DAS28 and DAS suggesting a direct role of the endogenous activation of these receptors in the control of RA joint inflammation.	22146575
Coronary Arteriosclerosis	Altered Intercellular Communication	Serum concentrations of IgG4 and sIL-2R were increased in patients with angiographically-proven CAD, suggesting that IgG4-related immuno-inflammation may also have a role in the development and/or progression of coronary artery atherosclerosis.	22146599
Inflammation, Ulcer	Altered Intercellular Communication	Nevertheless, after having stopped the inflammation, the ulcers can be treated by split thickness skin grafts and simultaneous immunosuppression.	22146897
Inflammation, leukemia	Altered Intercellular Communication	Gingival inflammation and platelet count in patients with leukemia: preliminary results.	22147236
vascular inflammations	Altered Intercellular Communication	Recent findings indicate that at least 2 separate lineages of CD4+ T cells, Th1 and Th17 cells, participate in vascular inflammation.	22147555
Symptoms, Inflammation, Thyroid Gland	Altered Intercellular Communication	The data included demographics, indication for surgery, compressive symptoms, complications, diagnosis, volume of thyroid gland, presence of inflammation, and follow-up.	22147633
Symptoms, Inflammation	Altered Intercellular Communication	There was not a significant relationship between compressive symptoms and the presence of inflammation (P=.869).	22147633
ARCN1 gene, Inflammation, Skeletal muscle weakness, Cachexia	Altered Intercellular Communication	COPD is a multicomponent disease and systemic inflammation represents one of the possible mechanisms responsible for its systemic manifestations, including skeletal muscle weakness and cachexia.	22149400
ARCN1 gene, Inflammation	Altered Intercellular Communication	We hypothesized that the multidimensional BODE index, that reflects the multicomponent nature of COPD, might be related to biomarkers of systemic inflammation.	22149400
ARCN1 gene, Inflammation	Altered Intercellular Communication	Systemic inflammation was evaluated with the measurement of leptin, adiponectin, CRP, IL-6, and TNF-a in serum samples of COPD patients.	22149400
ARCN1 gene, Inflammation, Muscular Atrophy	Altered Intercellular Communication	The additional association of FFMI with TNF-a may further support a role of systemic inflammation in muscle wasting in COPD.	22149400
Inflammation, Exanthema, Eccrine Glands, hyponatremic	Altered Intercellular Communication	In patients with PHA1, miliaria rubra-like cutaneous eruptions are suggested to occur due to obstruction of eccrine sweat glands through inflammation caused by excessive sodium excretion in sweat during hyponatremic crises.	22150373
Inflammation	Altered Intercellular Communication	The operation had been started laparoscopically and converted to an open procedure because of severe chronic or acute inflammation.	22151444
Inflammation	Altered Intercellular Communication	Extreme vasculobiliary injuries tend to occur when fundus-down cholecystectomy is performed in the presence of severe inflammation.	22151444
Acute inflammation	Altered Intercellular Communication	Contractive inflammation thickens and shortens the cystic plate, making separation of the gallbladder from the liver hazardous.	22151444
Inflammation, Injury wounds	Altered Intercellular Communication	Both chronic wounds and impaired acute wounds are characterized by excessive inflammation, enhanced proteolysis, and reduced matrix deposition.	22151742
Intraocular inflammation	Altered Intercellular Communication	The diagnosis of PE was defined as severe intraocular inflammation requiring prompt vitreous sampling for culture.	22151787
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation is a prominent feature in Alzheimer's disease (AD).	22152162
Inflammation	Altered Intercellular Communication	It has been proposed that aging has an effect on the function of inflammation in the brain, thereby contributing to the development of age-related diseases like AD.	22152162
Inflammation, Data types - Address	Altered Intercellular Communication	However, the age-dependent relationship between inflammation and clinical phenotype of AD has never been investigated.	22152162
Inflammation, Injury of liver	Altered Intercellular Communication	COX-2 expressed in liver may be a marker to reflect the degree of inflammation and injury of liver tissue.	22152242
Vasculitis, AAVS1 gene, Inflammation	Altered Intercellular Communication	In anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides (AAV), persistent inflammation within the vessel wall suggests perturbed neutrophil trafficking leading to accumulation of activated neutrophils in the microvascular compartment.	22152684
Inflammation	Altered Intercellular Communication	Down-regulation of these chemokine receptors could increase neutrophil adhesion and impair its migration through the glomerular endothelium, contributing to neutrophil accumulation and, in concert with ANCA, persistent inflammation within the vessel wall.	22152684
Inflammation	Altered Intercellular Communication	Biopsy showed chronic inflammation without any suspicion of malignity.	22153213
Inflammation, Necrosis, Refractory anemias, Atherosclerosis, Rheumatoid Arthritis	Altered Intercellular Communication	To examine how treatment of rheumatoid arthritis (RA) with anti-tumour necrosis factor alpha antagonists (anti-TNF) and B-cell targeting rituximab influences novel markers of atherosclerosis and inflammation, such as atheroprotective natural IgM antibodies against phosphorylcholine (anti-PC), oxidised low-density lipoprotein (oxLDL) and apolipoproteins.	22153361
Inflammation, Atherosclerosis	Altered Intercellular Communication	Body fat percentage as a risk factor for atherosclerosis but not for inflammation for hemodialysis patients: differences between genders.	22153383
Inflammation, Peripheral Arterial Diseases, Coronary Artery Disease	Altered Intercellular Communication	Serum paraoxonase-3 concentration is associated with insulin sensitivity in peripheral artery disease and with inflammation in coronary artery disease.	22153698
Inflammation, atherosclerotic	Altered Intercellular Communication	In both atherosclerotic phenotypes, serum PON3 concentration was increased, but this was associated with decreased insulin sensitivity in PAD and with inflammation in CAD.	22153698
Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Systemic lupus erythematosus (SLE), a prototypical autoimmune disease, often results in comorbidities from exposure to medications as well as from chronic inflammation.	22153881
Irritation - emotion, Inflammation, Muscle hypertrophy, Necrosis	Altered Intercellular Communication	Based on our patient material, we suggest that chronic nerve irritation, such as compression, can lead to muscle hypertrophy which, when prolonged, provokes fibre necrosis and secondary inflammation.	22153989
Inflammation, "Brodies abscess	Altered Intercellular Communication	Although microbiologic analysis of the surgical specimen failed to reveal a causative microorganism, histopathologic inspection showed chronic inflammation, consistent with Brodie's abscess.	22154059
Crohn Disease, Colorectal Carcinoma, Ulcerative Colitis	Altered Intercellular Communication	Inflammatory processes, including, specifically, the inflammatory conditions Crohn's disease (CD) and ulcerative colitis (UC) predispose to colorectal cancer.	22154103
Chronic disease	Altered Intercellular Communication	Inflammation increases with age and is associated with many chronic diseases that are prevalent among older adults.	22155500
Inflammation, Bacterial Infections	Altered Intercellular Communication	Persistent pathogens such as latent herpesviruses and chronic bacterial infections can act as a source of inflammation.	22155500
Inflammation	Altered Intercellular Communication	EBV and CMV replication can induce proinflammatory cytokine production and thus could influence systemic inflammation.	22155500
Inflammation	Altered Intercellular Communication	Thus, reactivation of multiple herpesviruses may drive inflammation and could contribute to poorer health among older adults.	22155500
Crohn Disease	Altered Intercellular Communication	Inflammation profile of four early onset Crohn patients.	22155628
Inflammation, Prediabetes syndrome, Gingival Hemorrhage	Altered Intercellular Communication	Self-perceived gingival bleeding and clinical periodontal inflammation were severe in patients with prediabetes as compared with controls.	22157389
Prediabetes syndrome	Altered Intercellular Communication	Comparison of self-perceived oral health, periodontal inflammatory conditions and socioeconomic status in individuals with and without prediabetes.	22157389
Inflammation, Intradermal Route of Drug Administration	Altered Intercellular Communication	Use of CF to adjust for inflammation increased the prevalence of ID based on ferritin < 12 mg/L by 34% (from 27 to 41%).	22157541
Inflammation, Intradermal Route of Drug Administration	Altered Intercellular Communication	Although the use of CF to adjust for inflammation appears indicated, further work is needed to confirm that this approach improves the accuracy of assessment of ID.	22157541
Inflammation, Atherosclerosis	Altered Intercellular Communication	The mechanism linking inflammation to atherosclerosis is unknown.	22157685
Inflammation, Cardiovascular Diseases, Interferon-Related DNA Damage Resistance Gene Signature, Coronary Artery Disease, Inflammatory disorder	Altered Intercellular Communication	We have previously demonstrated a high occurrence of inflammation in the aortic adventitia of patients with coronary artery disease (CAD), which was more pronounced in patients with inflammatory rheumatic diseases (IRDs), and which might be involved in the pathogenesis of cardiovascular disease.	22157685
vascular inflammations, Infection, Atherosclerosis	Altered Intercellular Communication	In theory, infections might play a role in the pathogenesis of vascular inflammation or atherosclerosis, or both.	22157685
immunoglobulin A	Altered Intercellular Communication	Mycoplasma IgA was related to a lower occurrence of aortic adventitial inflammation.	22157685
Communicable Diseases, Fasciitis, Inflammation, Necrosis	Altered Intercellular Communication	Necrotising fasciitis is an uncommon but life-threatening soft tissue infection characterised by rapidly spreading inflammation and necrosis of skin, subcutaneous fat and fascia.	22157919
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Influence of immune inflammation on androgen receptor expression in benign prostatic hyperplasia tissue.	22157983
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	This study was designed to investigate the association between immune inflammation and androgen receptor (AR) expression in benign prostatic hyperplasia (BPH).	22157983
Inflammation	Altered Intercellular Communication	An immune inflammation score for each specimen was defined by combining three immunohistochemical markers (CD4, CD8 and CD20).	22157983
Inflammation	Altered Intercellular Communication	Total prostate volume (TPV) was higher in the immune inflammation group than in the non-immune inflammation group (62.7 ml vs. 49.2 ml, t=2.482, P<0.05).	22157983
Inflammation	Altered Intercellular Communication	Patients in the immune inflammation group had a higher serum prostate-specific antigen (PSA) than those in the non-inflammation group (7.5 ng ml(-1 )vs. 5.4 ng ml(-1), t=2.771, P<0.05).	22157983
Inflammation	Altered Intercellular Communication	Specifically, the immune inflammation group showed a higher rate of AR expression than the non-inflammation group (56.1% vs. 28.2%, kh(2)=7.665, P<0.05).	22157983
Lung diseases, Malignant Neoplasms	Altered Intercellular Communication	Solitary pulmonary nodules can represent different specific lung diseases, focal non-specific inflammations, and primary and secondary malignant tumours.	22159242
Inflammation, Anterior Ischemic Optic Neuropathy	Altered Intercellular Communication	Cellular inflammation in nonarteritic anterior ischemic optic neuropathy and its primate model.	22159678
Infarction, Inflammation	Altered Intercellular Communication	Cellular inflammation plays a major early role following white-matter (optic nerve) infarct, with both polymorphonuclear leukocyte and macrophage function involved in debris elimination and tissue remodeling.	22159678
Inflammation, Optic Neuropathy	Altered Intercellular Communication	The optic nerve in NAION and its primate model are associated with early cellular inflammation, previously unsuspected, that may contribute to postinfarct optic nerve damage.	22159678
Inflammation, Bronchiolitis	Altered Intercellular Communication	Airway IFN-g production during RSV bronchiolitis is associated with eosinophilic inflammation.	22160185
Inflammation, Bronchiolitis	Altered Intercellular Communication	These results suggest that IFN-g may play an important role in eosinophilic inflammation in RSV bronchiolitis.	22160185
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	The present results show that the PC1 score is closely associated with parameters of MetS, inflammation and insulin resistance.	22160241
Inflammation, Crohn Disease	Altered Intercellular Communication	Computed tomography enterography (CTE) may detect the presence, severity, and extent of bowel inflammation in patients with Crohn's disease (CD).	22160373
Inflammation	Altered Intercellular Communication	CTE-WE represents a comprehensive imaging technique which may demonstrate bowel inflammation and CD extraintestinal manifestations.	22160373
Inflammation, Neoplasms	Altered Intercellular Communication	Thus, further appraisal of this novel method with inclusion of different tumour entities, systemic conditions and inflammation in a larger study population appears highly valuable.	22160580
Inflammation	Altered Intercellular Communication	Persistent H. pylori infection may affect the mucosal expression profiles of miRNAs via chronic inflammation mediated by proinflammatory cytokines.	22161133
Inflammation	Altered Intercellular Communication	This involves inflammation, epidermal differentiation, lipid metabolism, cell signalling and adhesion in response to FLG-dependent skin-barrier dysfunction.	22164253
Inflammation, myocardial injury	Altered Intercellular Communication	Does tight glucose control prevent myocardial injury and inflammation?	22164453
Communicable Diseases, Inflammation, Traumatic injury	Altered Intercellular Communication	There was no history of trauma, inflammation, or infection, and no significant urologic history.	22165050
Inflammation	Altered Intercellular Communication	Ferritin-based diagnosis of iron deficiency in these patients is a challenging task, as serum ferritin level may be high due to chronic inflammation and mask iron deficiency.	22165676
Inflammation, Kidney Failure	Altered Intercellular Communication	This study showed measurement of serum ferritin in the presence of chronic inflammation induced by renal failure cannot be a credible indicator of body iron supply, while under this certain condition serum transferrin receptor can more appropriately reflect the amount of body iron supply.	22165676
Inflammatory Bowel Diseases, Inflammation, Chronic disease	Altered Intercellular Communication	Inflammatory bowel disease (IBD) represents a heterogeneous group of chronic disorders characterized by inflammation of gastrointestinal tract, typically with a relapsing and remitting clinical course of unknown etiology.	22166284
Inflammation	Altered Intercellular Communication	The pathogenesis of IPEH might be related to inflammation or mechanical stimulus such as irritation.	22167033
Tuberculoma, Granulomatous inflammation	Altered Intercellular Communication	At surgery, a nodular, avascular lesion was found and pathological examination confirmed granulomatous inflammation suspecting tuberculoma.	22167292
Inflammation, Postoperative Period	Altered Intercellular Communication	Supra-physiological rhBMP loads during spinal fusion may trigger local inflammation and post-operative radiculitis.	22167451
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	This distribution is associated with an increased risk of type 2 diabetes and cardiovascular disease that are linked to low-grade inflammation.	22168600
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Advanced glycation end products (AGEs) are produced and can accumulate during chronic inflammation, as might be present in patients with rheumatoid arthritis (RA).	22168993
Ultraviolet B radiation, Inflammation, Age related macular degeneration, methyldopa	Altered Intercellular Communication	Ultraviolet B (UVB) radiation may cause the inflammation of retinal pigment epithelium (RPE) cells and play a role in development of age-related macular degeneration (AMD).	22169226
APP gene, Inflammation, Aneurysm	Altered Intercellular Communication	The purpose of the present study was to investigate the relationship between systemic expression of biomarkers of inflammation and extracellular matrix remodeling and aneurysm size in AAA patients.	22169593
Inflammation, Bacterial Infections	Altered Intercellular Communication	Further studies are warranted whether hantaviruses are setting the stage for a secondary bacterial infection or cause an inflammation itself.	22169597
Intraocular inflammation, Lesion of conjunctiva	Altered Intercellular Communication	In both cases, incomplete excision of conjunctival SCC was followed by rapid regrowth of the conjunctival lesion and signs of intraocular inflammation.	22169876
Inflammation, Endothelial Cells, Edema, Keratomileusis, Laser In Situ	Altered Intercellular Communication	To report a case of severe interface inflammation, flap edema, and endothelial cell loss after laser-assisted in situ keratomileusis (LASIK).	22169878
Inflammation	Altered Intercellular Communication	Evolutionarily conserved functions of PlGF-1 for placental phenomena are obviously also present in synovial inflammation.	22170453
Inflammation	Altered Intercellular Communication	Regenerative potential of human muscle stem cells in chronic inflammation.	22171690
Inflammation	Altered Intercellular Communication	Chronic inflammation is a profound systemic modification of the cellular microenvironment which could affect survival, repair and maintenance of muscle stem cells.	22171690
Inflammation, Muscle (organ)	Altered Intercellular Communication	The aim of this study was to define the role of chronic inflammation on the regenerative potential of satellite cells in human muscle.	22171690
Refractory anemias, Inflammation, Rheumatoid Arthritis, Degenerative polyarthritis	Altered Intercellular Communication	As a model for chronic inflammation, 11 patients suffering from rheumatoid arthritis (RA) were included together with 16 patients with osteoarthritis (OA) as controls.	22171690
Refractory anemias, Inflammation	Altered Intercellular Communication	In the present study we found evidence that chronic inflammation in RA does not affect the in vitro regenerative potential of human satellite cells.	22171690
Inflammation, Virus Diseases, Septic Shock	Altered Intercellular Communication	Viral infections in septic shock (VISS-trial)-crosslinks between inflammation and immunosuppression.	22172138
Neurogenic Inflammation, Complex Regional Pain Syndromes	Altered Intercellular Communication	There is evidence demonstrating that neurogenic inflammation and activation of the immune system play a significant role in the pathophysiology of CRPS.	22172450
Inflammation, Calcification of coronary artery	Altered Intercellular Communication	Association of systemic inflammation markers with the presence and extent of coronary artery calcification.	22172511
Inflammation, Hepatobiliary Disorder	Altered Intercellular Communication	TLR4-positive hepatic progenitor cells and interlobular bile ducts were significantly correlated with the stage of liver disease (P<0.001), the grade of inflammation (P<0.001), and the activity of portal/septal myofibroblasts (P<0.001).	22173288
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	TLR4 expression positively correlated with fibrosis (P<0.05) and inflammation (P<0.05).	22173288
Inflammation, Neoplasms	Altered Intercellular Communication	We conclude that MR imaging patterns can be possible manifestations of intravascular-dominant infiltration by tumor cells with associated occlusion or inflammation, depending on the level of affected vessels.	22173763
Inflammation	Altered Intercellular Communication	Galectins are a family of b-galactoside-binding proteins; by binding various glycoproteins, they play important roles in the regulation of cellular functions in inflammation and immunity.	22173878
Inflammation, Heart failure	Altered Intercellular Communication	Markers of inflammation are associated with increased risk of heart failure, but data on differential white blood cell (WBC) count are lacking.	22173908
Inflammation, Heart failure	Altered Intercellular Communication	Inflammation as measured by WBC count was independently associated with incident heart failure in apparently healthy men but not women.	22173908
Inflammation, CDISC SDTM Lesion Complexity Terminology	Altered Intercellular Communication	Factorial structure change during healthy ageing was associated with a decrease in complexity but showed an increase in variability and inflammation.	22174010
Weakness, Hypercalcemia, CTCAE, Hypokalemia, Epigastric pain, Anorexia, Nausea, Hypomagnesemia, Fatigue	Altered Intercellular Communication	This ECG concerns a 60-year-old male presented with general fatigue, weakness, epigastric pain, anorexia, nausea and extreme hypercalcemia (serum total and ionized calcium levels 20.5 mg/dL and 12.02 mg/dl, respectively), hypokalemia and hypomagnesemia associated with elevated parathyroid hormone (1160 pg/ml) and normal serum vitamin D level (97 ng/ml) .	22174173
Inflammation, Rheumatoid Arthritis, Dyslipidemias	Altered Intercellular Communication	Apolipoprotein E gene polymorphisms are strong predictors of inflammation and dyslipidemia in rheumatoid arthritis.	22174202
Refractory anemias, Inflammation, Dyslipidemias	Altered Intercellular Communication	Dyslipidemia in RA may be driven by inflammation and genetic factors.	22174202
Refractory anemias, Inflammation	Altered Intercellular Communication	We compared the frequency of 2 ApoE single-nucleotide polymorphisms (SNP) in patients with RA and controls, and studied the relationship of ApoE genotypes with lipids and inflammation in RA.	22174202
Refractory anemias, Inflammation	Altered Intercellular Communication	ApoE genotypes are strongly linked to inflammation and lipid levels in RA, raising interest in the prognostic implications of ApoE genotypes.	22174202
Inflammation	Altered Intercellular Communication	Fatty acid binding protein 4 (FABP4) has been shown to play an important role in macrophage cholesterol trafficking and associated inflammation.	22174896
Retinal Detachment, Inflammation, Nerve Degeneration	Altered Intercellular Communication	This systematic analysis confirmed the occurrence of both neurodegeneration and inflammation during retinal detachment, and further identifies precisely the modification of expression of the different genes implicated in these two phenomena.	22174898
Retinal Detachment, Inflammation, Photoreceptors	Altered Intercellular Communication	Our data henceforth give a new insight into the disease process and provide a rationale for therapeutic strategies aimed at limiting inflammation and photoreceptor damage associated with retinal detachment and, in turn, improving visual prognosis after retinal surgery.	22174898
Cartilage destruction, Inflammation, Retinitis Pigmentosa, polychondritis	Altered Intercellular Communication	relapsing polychondritis (RP) is a rare multisystem disease of unknown etiology, characterized by recurrent episodes of inflammation and cartilage destruction.	22176820
Inflammation, Carcinogenesis	Altered Intercellular Communication	The nuclear factor k-light-chain enhancer of activated B-cells (NF-kB) signaling pathway is regarded as an important factor in inflammation and carcinogenesis.	22176836
Inflammation	Altered Intercellular Communication	Total self-reported weekday sitting time was associated with biomarkers linked to chronic low-grade inflammation and poor metabolic health in women, but not men, independent of physical activity.	22176839
Inflammation, Sedentary lifestyle, Atherosclerosis	Altered Intercellular Communication	Sedentary behavior and adiposity-associated inflammation: the Multi-Ethnic Study of Atherosclerosis.	22176840
Inflammation	Altered Intercellular Communication	To determine the associations between sedentary behavior and measures of adiposity-associated inflammation.	22176840
Inflammation, Sedentary lifestyle	Altered Intercellular Communication	Sedentary behavior is associated with unfavorable levels of adiposity-associated inflammation.	22176840
ARCN1 gene, Inflammation, Pulmonary Emphysema, Osteoporosis	Altered Intercellular Communication	Disturbance of the OPG/RANK/RANKL pathway and systemic inflammation in COPD patients with emphysema and osteoporosis.	22176920
Inflammation	Altered Intercellular Communication	Analysis supported selective up-regulation of genes in the Hunner lesion interstitial cystitis/bladder pain syndrome group (hypothesis 3), which were primarily associated with inflammation.	22177197
Encephalopathy, CTCAE 5.0, White matter lesions, Neoplasms, Mitochondrial encephalopathy, Communicable Diseases, Venous Thrombosis, Demyelinating Diseases, Glioblastoma Multiforme Pathway, vascular inflammations	Altered Intercellular Communication	Among them, mitochondrial encephalopathy and vein thrombosis lesions located in the cortex; metastatic tumor and blood-borne infection mainly involving junction of grey and white matter; glioma, radiation encephalopathy and demyelinating disease include white matter lesions; vascular inflammation showed cortical and subcortical white matter lesions.	22177243
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	Among the various renal manifestations of sarcoidosis, granulomatous inflammation confined to the tubulointerstitial compartment is the most commonly reported finding.	22177616
Necrotizing granulomatous inflammation, Interstitial inflammation, Granulomatous Angiitis	Altered Intercellular Communication	Kidney biopsy showed diffuse interstitial inflammation with noncaseating granulomas that exhibited the unusual feature of infiltrating the walls of small arteries with destruction of the elastic lamina, consistent with granulomatous vasculitis.	22177616
Pain Distress Question, Inflammation	Altered Intercellular Communication	Further studies are warranted to elucidate the relation between bE and pain thresholds secondary to stress, inflammation, and discectomy.	22177809
Ischemia, Inflammation	Altered Intercellular Communication	Following ischemia, inflammation is provoked and related to the clinical outcomes.	22178059
Inflammation, Data types - Address	Altered Intercellular Communication	In conclusion, our study provides evidence for the first time that the functionality of HDL is impaired in AD and that this alteration might be caused by AD-associated oxidative stress and inflammation.	22178419
Inflammation, Pain Distress Question	Altered Intercellular Communication	The changes in total reaction moments and GRFs for only the NSAID suggest that greater increases in joint loading occurs when joint inflammation is treated in addition to pain.	22179861
Inflammation	Altered Intercellular Communication	It is associated with an unusual growth of fibrotic tissue admixed with varying amounts of inflammation that displaces and compresses normal anatomic structures, resulting in dysfunction.	22180112
Squamous cell carcinoma of the head and neck	Altered Intercellular Communication	Clinical observations and epidemiologic studies suggest that the incidence of head and neck squamous cell carcinoma (HNSCC) correlates with dental hygiene, implying a role for bacteria-induced inflammation in its pathogenesis.	22180460
Inflammation, Squamous cell carcinoma of the head and neck, Neoplasms	Altered Intercellular Communication	Methylation analysis in four genes (MDR1, IL8, RARB, TGFBR2) previously linked to HNSCC or inflammation shows significantly increased methylation in tumor samples compared with normal oral mucosa.	22180460
Inflammation, Depressed mood	Altered Intercellular Communication	As there are few studies on inflammatory markers that distinguish between depressed and nondepressed smokers, it is unclear if there is a cumulative impact of these mediators of inflammation.	22180575
Inflammation	Altered Intercellular Communication	However, an increased (18)FDG-tracer uptake at the thickened anterior leaflet indicated active inflammation.	22180605
Inflammation, Bioprosthesis device	Altered Intercellular Communication	In conclusion, our case indicates that (18)FDG-PET with cardiac CT image fusion may be a useful tool in patients with unclear focus of inflammation and possible bioprosthesis infection.	22180605
Sepsis, Inflammation, Abnormality of mitochondrial metabolism, cell injury	Altered Intercellular Communication	A plasmatic factor such as nitric oxide, increased in inflammation and able to induce mitochondrial dysfunction, oxidative stress and apoptosis, may be responsible for cell damage in sepsis.	22180620
Corneal stromal opacities, Conjunctivitis	Altered Intercellular Communication	The two groups also did not differ in terms of corneal opacification, visual acuity, conjunctival inflammation, and surgical complications.	22180732
Inflammation, Periodontitis, Chronic Kidney Diseases, Chronic inflammatory disorder	Altered Intercellular Communication	BACKGROUND AND OBJECTVE: Chronic inflammatory diseases have been investigated as a possible source of inflammation in chronic kidney disease patients; however, there is a shortage of information about the prevalence of periodontitis in such individuals.	22181057
Inflammation, Thickened	Altered Intercellular Communication	Nodules, thickening and inflammation were the most common in the videolaryngoscopy exams.	22183280
Inflammation, Thickened	Altered Intercellular Communication	Laryngeal lesions were found in the videolaryngoscopy exams, stressing nodules, thickening and inflammation.	22183280
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Data were correlated with body composition, emphysema and systemic inflammation.	22183483
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is associated with pulmonary and systemic inflammation.	22183488
Refractory anemias, Inflammation	Altered Intercellular Communication	A US score was designed to determine the degree of inflammation in the shoulder, the elbow, the hip, and the knee joint in patients with RA (Sonography of Large Joints in Rheumatology [SOLAR] score).	22183834
Airway structure, Inflammation, Arthritis, Refractory anemias	Altered Intercellular Communication	Airways abnormalities that are consistent with inflammation are common in autoantibody-positive subjects without inflammatory arthritis and are similar to airways abnormalities seen in patients with early RA.	22183986
Refractory anemias, Pneumonitis	Altered Intercellular Communication	Further studies are needed to define the mechanistic role of lung inflammation in the development of RA.	22183986
Natriuresis	Altered Intercellular Communication	Activation of hormonal changes that regulate depressor responses to salt depletion may not have occurred with the 3-hour natriuresis of the short protocol.	22184320
Communicable Diseases, Inflammation	Altered Intercellular Communication	Reduced inflammation and altered innate response in neonates during paramyxoviral infection.	22185352
Inflammation	Altered Intercellular Communication	Importantly, the expression of the RIG-I-like receptors (RLRs) was delayed in the neonatal mice, which might have contributed to their reduced inflammation and differential cytokine expression.	22185352
Pneumonitis	Altered Intercellular Communication	Neonatal mice developed similar SeV titers and cleared the virus with similar efficiency despite developing a dramatically lower degree of pulmonary inflammation compared to adults.	22185352
Inflammation	Altered Intercellular Communication	This suggests that inflammation in the lung may not be required to control viral replication.	22185352
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	This study demonstrates that TLR2, TLR4, TLR8, and TLR9 expression increases in active UC patients, and that the mRNA levels positively correlate with the severity of intestinal inflammation as well as with inflammatory cytokines.	22185629
Multiple Myeloma, Hypercalcemia, CTCAE	Altered Intercellular Communication	A case of myeloma with hypercalcemia caused by high serum concentrations of both parathyroid hormone-related peptide (PTHrP) and macrophage inflammatory protein-1a (MIP-1a).	22185991
Inflammation, Takayasu Arteritis, Arteritis	Altered Intercellular Communication	Surgical repair of these lesions can be compromised by the chronic inflammation of Takayasu's arteritis.	22186452
Psoriasis, Psoriasiform lesion	Altered Intercellular Communication	Psoriasis and psoriasiform lesions were documented in 7 patients diagnosed with different rheumatic inflammatory conditions (1.56%).	22187056
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Increasing evidence supports a role for inflammation in promoting atrial fibrillation (AF) and statins have anti-inflammatory effects that may be relevant for the prevention of AF.	22187510
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Long-term outcome of patients with distal ulcerative colitis and inflammation of the appendiceal orifice.	22187699
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Skip inflammation of the appendiceal orifice has been described in distal UC (UC-IAO) but long-term clinical outcomes are poorly established.	22187699
Hepatic inflammation, Hepatitis	Altered Intercellular Communication	These results suggest that the reduced expression of B7-H3 in the livers might temper the inhibition of T-cell responses mediated by B7-H3 expressed on hepatocytes and thus promote the hepatic inflammation and hepatitis progression in the chronic HBV-infected patients.	22187944
Inflammation, Dental Plaque	Altered Intercellular Communication	Oral hygiene was registered with Mucosal-Plaque Score, an index based on assessment of plaque accumulation and mucosal/gingival inflammation.	22187971
Inflammation, Fracture, Bipolar Disorder	Altered Intercellular Communication	Results from these exploratory analyses support a role for inflammation in the pathophysiology of depressive symptoms after hip fracture.	22188073
Attention deficit hyperactivity disorder, Sleep disturbances	Altered Intercellular Communication	The high rate of occurrence of sleep disturbances in children with attention-deficit/hyperactivity disorder (ADHD) prompted the idea that structural and neurotransmitter changes might give rise to specific sleep pattern abnormalities.	22188114
Inflammation, Cerebral Infarction, Vasculitis, CTCAE	Altered Intercellular Communication	Multiple cerebral infarcts with a few vasculitic lesions in the chronic stage of cerebral amyloid angiopathy-related inflammation.	22188118
Cerebral Amyloid Angiopathy, Inflammation	Altered Intercellular Communication	We report a 75-year-old man with a 3.5-year history of cerebral amyloid angiopathy (CAA)-related inflammation.	22188118
Vasculitis, CTCAE	Altered Intercellular Communication	In conclusion, we consider that, although the association of PR3-ANCA with the pathogenesis of Ab-associated vasculitis remained unclear, the present case represents a rare example of CAA-related inflammation at the chronic stage.	22188118
Inflammation, atherosclerotic	Altered Intercellular Communication	Our understanding of chronic inflammation in CKD-5D and of its influence in the accelerated atherosclerotic process has greatly evolved.	22188694
Hypernatremia, Inflammation, Electrocardiogram: left ventricle hypertrophy (finding), Anemia	Altered Intercellular Communication	There is sufficient evidence to indicate that on-line hemodiafiltration has the potential to improve chronic inflammation, fluid overload, left ventricular hypertrophy, anemia and quality of life of CKD-5D patients.	22188694
Inflammation, Italy, Anemia	Altered Intercellular Communication	Here, we intend to present new insights obtained from a prospective observational study (RISCAVID, 'RISchio CArdiovascolare nei pazienti afferenti all'Area Vasta In Dialisi') performed on a large HD population in the northwestern region of Tuscany, Italy, on the assessment of the different parameters of chronic inflammation and gross/CV mortality and anemia management.	22188694
Impaired cognition, millicurie	Altered Intercellular Communication	Acetylcholine, the main neurotransmitter of the parasympathetic system may be deficient in mild cognitive impairment (MCI).	22188719
Inflammation, Intermittent fever (finding)	Altered Intercellular Communication	Incomplete Kawasaki disease with intermittent fever and retropharyngeal inflammation.	22189530
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Abundant evidence supports the hypothesis that inflammation plays an important role in the development of coronary artery disease (CAD).	22189538
Inflammation, Benign prostatic hypertrophy, Prostate carcinoma, Neoplasms	Altered Intercellular Communication	Serum levels of secreted group IIA phospholipase A(2) in benign prostatic hyperplasia and prostate cancer: a biomarker for inflammation or neoplasia?	22189868
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	In conclusion, these findings suggest that cancer-related changes are not exclusive factors contributing to elevated serum sPLA(2)-IIA levels and emphasize the utility of sPLA(2)-IIA as a circulating marker of inflammation in patients with BPH and PCa.	22189868
Inflammation, Necrosis, Fibrosis Assessment, Hyperplastic Polyp, Retractile Mesenteritis	Altered Intercellular Communication	I can be evaluated as a single disease with two pathological subgroups: MP, representing the very large majoritary subgroup where inflammation and fat necrosis predominate and Retractile Mesenteritis, rarely found, where fibrosis and retraction predominate.	22191288
Mesenteric Panniculitis, Hyperplastic Polyp	Altered Intercellular Communication	Mesenteric panniculitis (MP) is an uncommon benign inflammatory condition of unknown etiology that involves the adipose tissue of the mesentery.	22191288
Inflammation, Necrosis	Altered Intercellular Communication	A thoracoscopic lung biopsy of the upper left lobe revealed necrosis of lung tissue, with acute and chronic inflammation of the cavity wall and the presence of hyphae consistent with Aspergillus species.	22191319
Inflammation, dendritic lamellar body, Data types - Address	Altered Intercellular Communication	Correlations between HA levels and markers of inflammation and vascular changes were only detected in female AD patients but in both male and female DLB patients.	22191565
Airway structure, Wheezing	Altered Intercellular Communication	We demonstrated that 5 yr old children with persistent wheeze already had elevated exhaled inflammatory markers at preschool age compared to never wheezers, indicating augmented airway inflammation in these children.	22192238
Inflammation, Congestive heart failure	Altered Intercellular Communication	Diffuse inflammation is also prominent in CHF and a potent inhibitor of erythrocyte production.	22192286
Inflammation, Dysplasia, Carcinoma, Communicable Diseases, Squamous metaplasia	Altered Intercellular Communication	Chronic irritation, inflammation, and infection induce squamous metaplasia of the renal collecting system, which may progress to dysplasia and carcinoma in most of affected individuals.	22192451
Congenital Abnormality	Altered Intercellular Communication	We hypothesize whether transient arterial wall abnormalities, postpartum hormonal changes or subtle connective tissue aberrations play a similar role in the pathogenesis of these two associated conditions.	22192555
Inflammation, Observation Method - Coagulation, TYPHUS	Altered Intercellular Communication	Coagulation and inflammation in scrub typhus and murine typhus--a prospective comparative study from Laos.	22192733
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	The current understanding of coagulation and inflammation in the pathogenesis of these clinically very similar vasculotropic diseases is limited.	22192733
Inflammation, Damage	Altered Intercellular Communication	Functional mutations in the genes related to innate immune response exacerbate mucosal damage coupled with persistent inflammation.	22192785
Inflammation, Hydrarthrosis	Altered Intercellular Communication	To investigate which knee and probe position best identifies knee inflammation and to determine a cut-off level for abnormal synovial effusion.	22194046
Necrotizing granulomatous inflammation, Infectious Lung Disorder, Bronchiectasis	Altered Intercellular Communication	Bronchiectasis with cavity formation and necrotizing bronchocentric granulomatous inflammation predominated but extrapulmonary infection was absent.	22194586
Granulomatous inflammation	Altered Intercellular Communication	Miliary nodules and/or consolidation with poorly formed granulomatous inflammation were noted in the three disseminated patients with mycobacterial lung involvement.	22194586
Chronic inflammation	Altered Intercellular Communication	Excluding recent smoking is therefore important in clinical studies with chronic inflammation as primary focus.	22194931
Inflammation, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Recent studies have suggested that mast-cell activation and inflammation are important in obesity and diabetes.	22194960
Dryness of eye, Conjunctivitis	Altered Intercellular Communication	RAG1KO recipients of adoptively transferred CD4+T cells isolated from DS5 CD4-DNTGFbRII showed milder dry eye phenotype and less conjunctival inflammation than recipients of WT control.	22194977
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The relationship of these novel candidate biomarkers with cancer and inflammation suggests that they are truly associated with HL and therefore may be useful for the early detection of this cancer in susceptible populations.	22195036
Inflammation, Vegetation	Altered Intercellular Communication	The infected valve did not show vegetations or perforations, but histiocytic inflammation was seen along the endocardial surfaces of the valve.	22196518
SLC5A8 wt Allele, Cardiac dysfunction	Altered Intercellular Communication	AIT effectively improves oxygen uptake efficiency by enhancing cerebral/muscular hemodynamics and suppresses oxidative stress/inflammation associated with cardiac dysfunction, and also promotes generic/disease-specific qualities of life in patients with HF.	22197120
Inflammation, Corneal Ulcer, corneal melt	Altered Intercellular Communication	Two male patients, 80 and 60 years old, with persistent corneal ulcerations, corneal melting, and inflammation some months after an LS episode.	22197436
Inflammation, Metabolic Syndrome X, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation and oxidative stress plays a critical role in cardiovascular disease and metabolic syndrome often occurs with these two variables.	22197455
Parkinsonian Disorders	Altered Intercellular Communication	This post-hoc functional analysis identified early-onset changes in Parkinsonian, immune and alternative splicing pathways which shifted into late-onset or exposure-associated NFkB-mediated neuro-inflammation.	22198569
Stomach Carcinoma	Altered Intercellular Communication	Comparison of the prognostic value of various preoperative inflammation-based factors in patients with stage III gastric cancer.	22198641
Chronic lymphocytic inflammation, Inflammation, Necrosis	Altered Intercellular Communication	While MRI showed increased signal intensity on T2-weighted images of the leg muscles, indicating inflammation, muscle biopsy found widespread necrosis with only weak and focal lymphocytic infiltration.	22198662
Inflammation, Necrosis	Altered Intercellular Communication	A repeat MRI showed progression of inflammation, as well as necrotic foci.	22198662
ARCN1 gene, Inflammation	Altered Intercellular Communication	The association of low bone mineral density with systemic inflammation in clinically stable COPD.	22198912
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Inflammatory disorder	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is known to be a systemic inflammatory disease which affects the function of many organs, and the low bone mineral density (BMD) may be the result of systemic inflammation.	22198912
ARCN1 gene, Inflammation	Altered Intercellular Communication	The aim of the present study was to explore the association of BMD with systemic inflammation in patients with clinically stable COPD.	22198912
Inflammation, Osteoporosis	Altered Intercellular Communication	The patients were classified according to T scores, and the relationship between BMD with markers of systemic inflammation and that with other osteoporosis risk factors was assessed.	22198912
ARCN1 gene, Inflammation, Osteoporosis, Osteopenia	Altered Intercellular Communication	As the abnormality of BMD went severer, COPD patients with osteoporosis had significantly higher levels of systemic inflammation than those with either normal BMD or osteopenia.	22198912
ARCN1 gene, Inflammation	Altered Intercellular Communication	It can be concluded that systemic inflammation is a significantly independent predictor of low BMD in patients with clinically stable COPD.	22198912
Ocular Hypertension, Embolism, Amniotic Fluid, Inflammation, Keratomileusis, Laser In Situ	Altered Intercellular Communication	This case illustrates that interface fluid syndrome can develop more than 10 years after LASIK, triggered by ocular hypertension and inflammation after intraocular surgery.	22200509
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Neutrophil gelatinase-associated lipocalin (NGAL) in inflammatory bowel disease: association with pathophysiology of inflammation, established markers, and disease activity.	22200942
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Serum NGAL is elevated particularly in active IBD and correlates with established markers of inflammation and disease activity, implicating its role in the pathophysiology of IBD.	22200942
Inflammation, Infectious Lung Disorder, Bronchiectasis	Altered Intercellular Communication	Radiological progression of bronchiectasis and air trapping was associated with severe CFTR genotype, worsening neutrophilic inflammation and pulmonary infection.	22201161
Inflammation, Infectious Lung Disorder, Lung diseases	Altered Intercellular Communication	CT-detected structural lung disease identified in infants and young children with CF persists and progresses over 1 year in most cases, with deteriorating structural lung disease associated with worsening inflammation and pulmonary infection.	22201161
Inflammation	Altered Intercellular Communication	Evidence suggests that immunological response in chronic inflammation is dynamic, oscillating between active immunity and tolerance.	22201928
Malignant neoplasm of liver, Inflammation	Altered Intercellular Communication	Interactions between the activated lymphocytes and liver cancer cells increased levels of serum a1AG, an inflammation marker, but these levels normalized following the sixth and final administration.	22202430
Acute inflammation, Colorectal Carcinoma	Altered Intercellular Communication	DKT administration also significantly suppressed postoperative inflammation following surgery for colorectal cancer.	22202972
Sepsis, Postoperative sepsis, Peritonitis	Altered Intercellular Communication	Pro- and anti-inflammatory cytokine production was investigated in patients with postoperative sepsis, a murine peritonitis model and in vitro to further delineate the interaction of hyper- and hypo-inflammation in sepsis.	22204813
Inflammation	Altered Intercellular Communication	In 1309 joints that were not clinically involved, US detected signs indicative of joint inflammation in 9% (121/1309).	22206648
Inflammation, El Salvador	Altered Intercellular Communication	These studies demonstrate that markers of inflammation are upregulated in response to SV distention.	22206954
Inflammation, Narcolepsy, Dental Plaque	Altered Intercellular Communication	Studies showing an association between the neuropeptide orexin and AD/DLB-related processes such as amyloid-b (Ab)1-42 plaque formation, a-synuclein accumulation and inflammation indicate that orexin might play a pathogenic role similar to the situation in narcolepsy.	22207004
Gastrointestinal inflammation	Altered Intercellular Communication	Our findings suggest that different immunopathogenetic pathways underlie chronic intestinal inflammation with different clinical expressions.	22208453
Airway structure	Altered Intercellular Communication	Ventilatory lung function was measured by spirometry and airway inflammation by exhaled nitric oxide (eNO).	22208751
Inflammation, Muscular Atrophy	Altered Intercellular Communication	Inflammation is the main cause of disease-associated muscle wasting.	22208783
Inflammation	Altered Intercellular Communication	We hypothesized that NSAID treatment would preserve muscle performance better than antibiotic treatment alone, by reducing infection-associated inflammation and by increasing expression of cytoprotective Hsp.	22208783
Acute inflammation	Altered Intercellular Communication	Piroxicam improves clinically relevant measures of muscle performance and mobility in geriatric patients hospitalized with acute infection-induced inflammation.	22208783
Tumor necrosis, Inflammation, Zinc deficiency	Altered Intercellular Communication	Interleukin-6 and tumor necrosis factor-a overproduction was enhanced in old individuals, suggesting the presence of more marked zinc deficiency and chronic inflammation.	22209006
Inflammation	Altered Intercellular Communication	Evidence suggests that SCD1 activity may be positively associated with inflammation.	22209225
Inflammation	Altered Intercellular Communication	Overall, SCD1 activity and genetic variation have an important role in modulating the relationship between FA and inflammation in young adults.	22209225
Inflammation, Melanosis, Hyperplasia, Hemorrhage	Altered Intercellular Communication	There was no inflammation or hemorrhage, and no melanosis or melanocytic hyperplasia in the epithelium.	22209988
Inflammation, Burn injury	Altered Intercellular Communication	Characterizing the sensation and affective itch dimensions in conjunction with inflammation, burn injury, recovery, scar maturation, medication, and psychological status should better elucidate postburn itch.	22210065
Inflammatory abnormality of the eye	Altered Intercellular Communication	In this case, a 43-year-old male patient diagnosed with AOSD showed ocular inflammation after withdrawing from corticosteroid treatment.	22210274
Prostate carcinoma	Altered Intercellular Communication	Androgen deprivation, the cornerstone of treatment for patients with metastatic prostate cancer, has been shown to elicit prostate tissue apoptosis and lymphocytic inflammation.	22210552
Refractory anemias, Inflammation	Altered Intercellular Communication	The 6-joint ultrasonographic assessment: a valid, sensitive-to-change and feasible method for evaluating joint inflammation in RA.	22210661
Refractory anemias, Inflammation	Altered Intercellular Communication	A 6-joint US assessment may be a valid, sensitive-to-change and feasible method for evaluating joint inflammation in RA.	22210661
Inflammation, Keloid, Burn injury, Traumatic injury	Altered Intercellular Communication	Keloid represents an exuberant wound healing response, usually secondary to trauma, inflammation, surgery, or burns.	22210735
Inflammation, Fever, CTCAE, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Patients with myocarditis were younger and more often presented with signs of inflammation such as elevated C-reactive protein and fever.	22210737
Inflammation	Altered Intercellular Communication	In summary, binding of leukocytes to activated endothelium mediated by the interaction of CD97 with Thy-1 is involved in firm adhesion of PMNC during inflammation and may play a role in the regulation of leukocyte trafficking to inflammatory sites.	22210915
Inflammation	Altered Intercellular Communication	The number of DMBT1-positive HPCs increased in direct proportion to inflammation severity.	22211283
Head of pancreas, Perifolliculitis	Altered Intercellular Communication	Whipple specimens from two patients with a pancreatic head mass showed similar follicular inflammation histologically around bile ducts.	22211284
Pancreaticobiliary Maljunction, Primary sclerosing cholangitis, Autoimmune Pancreatitis, Waldenstrom Macroglobulinemia, Cholangitis	Altered Intercellular Communication	Biliary and pancreatic ductal systems can be involved in several lymphoplasmacytic inflammatory conditions, including primary sclerosing cholangitis, immunoglobulin G (IgG) 4-related cholangitis and autoimmune pancreatitis.	22211284
mucosa-associated lymphoid tissue, Inflammation, IgG4-Related Sclerosing Disease, Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	Making a differential diagnosis of IgG4-related disease from mucosa-associated lymphoid tissue (MALT) lymphoma or any other chronic inflammation is often challenging.	22211288
Inflammation, IgG4-Related Sclerosing Disease, Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	The number of IgG4-positive cells and the ratio of IgG4/IgG-positive cells were higher in patients with IgG4-related disease than in those with MALT lymphoma (P = 0.016; P < 0.001) and other types of inflammation (P < 0.001; P < 0.001).	22211288
Inflammation, IgG4-Related Sclerosing Disease, Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	Regulatory T-cell infiltration was higher in cases of IgG4-related disease than in MALT lymphomas (P < 0.001) and other types of inflammation (P = 0.006).	22211288
IgG4-Related Sclerosing Disease, Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	We investigated 14 cases of IgG4-related disease, nine MALT lymphomas and 12 other chronic inflammations involving the lacrimal gland and orbit.	22211288
IgG4-Related Sclerosing Disease, Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	Ocular adnexal IgG4-related disease: comparative analysis with mucosa-associated lymphoid tissue lymphoma and other chronic inflammatory conditions.	22211288
Inflammation, Atherosclerosis	Altered Intercellular Communication	Lipoprotein-associated phospholipase A2 (LpPLA2) is a lipoprotein-bound enzyme involved in inflammation and atherosclerosis.	22211481
Inflammation, Injury of kidney	Altered Intercellular Communication	Neutrophil gelatinase-associated lipocalin is a marker of kidney injury as well as matrix degradation and inflammation and has previously been shown to be increased in HF.	22211640
Inflammation, Musculoskeletal Pain, Collagen Diseases	Altered Intercellular Communication	Polymyalgia rheumatica (PMR) is a rheumatic disease that is characterized by intense activation of systemic inflammation.	22211720
Inflammation, Endothelium	Altered Intercellular Communication	Systemic inflammation has been associated with an imbalance between endothelial injury and repair, defined by an increased number of circulating endothelial microparticles (EMPs) and a reduced number of endothelial progenitor cells (EPCs).	22211720
Inflammation, Endothelium, Musculoskeletal Pain	Altered Intercellular Communication	Polymyalgia rheumatica is associated with a significant imbalance between endothelial injury and repair, which is dependent on the degree of systemic inflammation.	22211720
Inflammation, Fatty degeneration of heart, Hemorrhage of kidney, Fibrous, Bronchopneumonia	Altered Intercellular Communication	At autopsy chronic inflammation of the thyroid gland, bronchopneumonia, fibrous and fatty heart degeneration and kidney haemorrhagic infarcts were documented.	22212924
Inflammation, Carotid Stenosis, Coronary Arteriosclerosis, Coronary Artery Disease	Altered Intercellular Communication	In patients with severe carotid stenosis and nonsignificant coronary artery disease, inflammation is associated with atherosclerotic disease activity and a worse prognosis.	22212968
Pancreatitis, Acute, Inflammation, Observation Method - Coagulation, Single organ dysfunction	Altered Intercellular Communication	Being a central link between inflammation and coagulation, tissue factor (TF) and its inhibitor (TFPI) might be associated with the severity of acute pancreatitis (AP) and the development of organ failure (OF).	22213026
Fibrosis Assessment, Liver damage, Portal inflammation	Altered Intercellular Communication	Increased HH activity (evidenced by accumulation of HH-ligand-producing cells and HH-responsive target cells) strongly correlated with portal inflammation, ballooning, and fibrosis stage (each P < 0.0001), supporting a relationship between HH-pathway activation and liver damage.	22213086
Presenile dementia, Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Biomarkers for insulin resistance and inflammation and the risk for all-cause dementia and alzheimer disease: results from the Framingham Heart Study.	22213409
Presenile dementia, Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	To investigate the contribution of biomarkers of glucose homeostasis (adiponectin, glucose, glycated albumin, and insulin levels) and inflammation (high-sensitivity C-reactive protein and lipoprotein-associated phospholipase A(2) levels) to the risk of developing Alzheimer disease (AD) and all-cause dementia.	22213409
Inflammation	Altered Intercellular Communication	It has also been shown that ethnicity may be a factor in affecting systemic inflammation, and limited evidence suggests it may influence plasma LC-PUFA composition.	22215136
Inflammation	Altered Intercellular Communication	Ethnicity did not modify the associations of LC-PUFAs with markers of inflammation or endothelial activation (all P (interaction)>0.05).	22215136
Alzheimers Disease", Inflammation	Altered Intercellular Communication	Gene expression variation could be almost completely explained by four transcriptional biomarkers that we named BioAge (biological age), Alz (Alzheimer), Inflame (inflammation), and NdStress (neurodegenerative stress).	22216330
Inflammation, Necrosis	Altered Intercellular Communication	We propose that the underlying initial condition in its pathogenesis is reduced ability of the neonatal gut epithelial cells (NGECs) to clear oxidative stress (OS), and that when such a NGEC population is exposed to enteral feeding, the increased metabolic OS tips the population toward apoptosis, inflammation, bacterial activation, and eventual necrosis.	22217195
Necrotizing enterocolitis in fetus OR newborn, Inflammation, Necrosis	Altered Intercellular Communication	Reduction in OS clearance consistent with clinical NEC led to senescence, apoptosis, or inflammation, with disruption of tight junctions, but rarely to NGEC necrosis.	22217195
Necrotizing enterocolitis in fetus OR newborn, Inflammation, Necrosis	Altered Intercellular Communication	Our ABM incorporates known components of NEC and demonstrates that impaired OS management can lead to apoptosis and inflammation of NGECs, rendering the system susceptible to an additional insult involving regionalized mucus barrier failure and TLR-4 activation, which potentiates the necrosis outcome.	22217195
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	Histopathological examination of skin biopsies showed granulomatous inflammation, suggestive for sarcoidosis.	22217306
Inflammation, Asthma	Altered Intercellular Communication	These preliminary findings suggest that EMID2_BL1_ht2 may be a susceptibility marker of inflammation of the nasal passages among Korean asthma patients.	22217332
Orbital Pseudotumor	Altered Intercellular Communication	[Management of orbital inflammation in internal medicine: a retrospective case series of 29 patients].	22217923
Inflammation, Orbital Pseudotumor	Altered Intercellular Communication	To describe a case series of patients investigated in internal medicine for an inflammation of the orbit and to clarify the clinical and pathological features of patients with idiopathic orbital inflammatory syndrome (IOIS).	22217923
Inflammation, Aplasia of the parotid gland	Altered Intercellular Communication	Recurrent inflammation of accessory parotid tissue associated with unilateral parotid gland aplasia: diagnostic and therapeutic implications.	22218848
Inflammation, Fatty Liver Disease	Altered Intercellular Communication	NASH patients presented a weak negative correlation between lobular inflammation and Bcl-2 levels.	22219597
Pain Distress Question, Inflammation, Degenerative polyarthritis, Functional Disability, Impaired	Altered Intercellular Communication	Knee osteoarthritis (KOA), the most common type of osteoarthritis (OA), is associated with pain and inflammation of the joint capsule, impaired muscular stabilization, reduced range of motion and functional disability.	22220431
Inflammation, Psoriasis, Dermatitis, RANGAP1 wt Allele, Pruritus	Altered Intercellular Communication	As the inflammatory scalp conditions share similar clinical manifestations of scaling, inflammation, and pruritus, the differential diagnosis of these lesions; especially between scalp psoriasis (SP) and seborrheic dermatitis (SD) is sometimes difficult.	22220807
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Berberine ameliorates inflammation in patients with acute coronary syndrome following percutaneous coronary intervention.	22220931
Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation is central to the pathogenesis of acute coronary syndrome (ACS) and is associated with adverse clinical outcomes after percutaneous coronary intervention (PCI).	22220931
Multiple Organ Failure, Inflammation, Fracture	Altered Intercellular Communication	Early intramedullary nailing (IMN) of long bone fractures in severely injured patients has been evaluated as beneficial, but has also been associated with increased inflammation, multi organ failure (MOF) and morbidity.	22221511
Electrocardiogram: myocardial infarction (finding), Myocarditis	Altered Intercellular Communication	The aim of this study was to explore post-myocardial infarction (MI) myocardial inflammation.	22222080
Infarction, Inflammation	Altered Intercellular Communication	Cell depletion and isolation data confirmed that this largely reflected inflammation; CD11b(+) cells had 4-fold higher (18)FDG uptake than the infarct tissue from which they were isolated (p < 0.01).	22222080
Inflammatory abnormality of the eye, Panuveitis	Altered Intercellular Communication	Cases of ocular inflammation following penetration by urticating hairs from caterpillars and tarantulas have been previously reported and although rare, the condition is increasingly being recognised as a cause of chronic panuveitis.	22222718
vascular inflammations	Altered Intercellular Communication	Recent studies suggested an important role for regulatory T (Treg) cells in the inhibition of disease-related vascular inflammation.	22223728
vascular inflammations, Dental Plaque	Altered Intercellular Communication	Limitation of plaque progression was associated with reduced vascular inflammation and increased collagen content, indicative of plaque stabilization.	22223728
Inflammation, Atrial Fibrillation by ECG Finding, Diabetes Mellitus, Cerebrovascular accident, Endothelial dysfunction, Obesity	Altered Intercellular Communication	The increased risk of HF associated with elevated GGT persisted after adjustment for a wide range of established and novel risk factors for HF, including diabetes, stroke, obesity, systolic blood pressure, atrial fibrillation, lung function, inflammation (C-reactive protein), endothelial dysfunction (von Willebrand factor), leptin, and N terminal pro brain natriuretic peptide (adjusted hazard ratio [95% CI], 1.91 [1.07, 3.42]).	22223732
Inflammation, Joints, Synovitis	Altered Intercellular Communication	The presence of low-grade inflammation in OA joints is receiving increasing attention, with synovitis shown to be present even in the early stages of the disease.	22225630
Inflammation	Altered Intercellular Communication	How the synovial inflammation arises is unclear, but proteins in the synovial fluid of affected joints could conceivably contribute.	22225630
Inflammation	Altered Intercellular Communication	We identified 108 proteins in OA synovial fluid, including plasma proteins, serine protease inhibitors, proteins indicative of cartilage turnover, and proteins involved in inflammation and immunity.	22225630
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Our findings suggest that plasma proteins present in OA synovial fluid, whether through exudation from plasma or production by synovial tissues, could contribute to low-grade inflammation in OA by functioning as so-called damage-associated molecular patterns in the synovial joint.	22225630
Chronic inflammation, Abnormal degeneration	Altered Intercellular Communication	The accumulation of LPC (1-acyl 16:0) and PC (diacyl 16:0/20:4) in the VV intima and media may be associated with chronic inflammation, leading to VV tissue degeneration.	22226181
Helicobacter heilmannii, Acute and chronic inflammation	Altered Intercellular Communication	Chronic active inflammation was observed in 53(56%) (p = 0.001) of the patients with H. pylori infection alone as compared to 3(37%) (p = 0.73) coinfected with H. heilmannii and H. pylori and 3(60%) coinfected with H. felis and H. pylori (p = 0.66).	22226326
Inflammation, Spondylarthritis	Altered Intercellular Communication	Anterior chest wall inflammation by whole-body magnetic resonance imaging in patients with spondyloarthritis: lack of association between clinical and imaging findings in a cross-sectional study.	22226453
Cerebrovascular Disorders, Inflammation	Altered Intercellular Communication	Systemic arterial inflammation, measured with 18FDG-PET, is common amongst subjects with both recent and prior cerebrovascular disease.	22226631
Cerebrovascular Disorders, Inflammation, Tacca leontopetaloides, Ischemic stroke	Altered Intercellular Communication	To compare systemic arterial inflammation in subjects with recent ischaemic stroke or TIA and controls with prior cerebrovascular disease.	22226631
Cerebrovascular Disorders, Inflammation, Tacca leontopetaloides, Ischemic stroke	Altered Intercellular Communication	Systemic arterial inflammation was prospectively measured by (18)F-fluorodeoxygluose positron emission tomography in 11 cases with recent ischaemic stroke or TIA, and 11 sex matched controls with prior cerebrovascular disease.	22226631
Inflammation	Altered Intercellular Communication	Arterial inflammation was common, and appeared similar, in patients with recent stroke/TIA, and controls with stroke/TIA more than two years previously.	22226631
Inflammation	Altered Intercellular Communication	Interestingly, immunoglobulin free light chains (IgLC) are able to prolong the life of neutrophils; therefore, IgLC may contribute to the chronic state of inflammation.	22227380
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Previous studies suggest that inflammation plays an important part in the pathogenesis of diabetes.	22227739
Inflammation, Coronary heart disease	Altered Intercellular Communication	Inflammation plays a pivotal role in coronary heart disease.	22227998
Inflammation, Atherosclerosis	Altered Intercellular Communication	Dendritic cells (DCs) are principal players in inflammation and atherosclerosis.	22227998
Lymphoid nodule, Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The number of CD4(+), CD25(+), and Foxp3(+) cells, and the ratio of CD25(+)/CD4(+) and Foxp3(+)/CD4(+) cells, were associated with the histological grade of the specimens, including acute inflammation, chronic inflammation, lymphoid follicle number, and Helicobacter pylori infection.	22228968
Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	Pseudoseptic arthritis is primarily described in rheumatoid arthritis and other systemic inflammatory conditions.	22229599
Inflammation, Hematoma, Hemorrhage	Altered Intercellular Communication	On physical examination, a painful mass in the hypogastrium and intense inflammation in the thigh and the proximal portion of left knee were found.Emergent multiphase contrast computed tomography revealed a large nonhomogeneous hematoma neighboring the fractured left iliopubic rami, and contrast extravasation indicated arterial bleeding.	22229619
Inflammatory Bowel Diseases, Crohn Disease, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The newly described--multigene analysis test (DiBiCol) identifying 7 inflammatory bowel disease (IBD)-specific genes in colonic mucosal biopsy differentiating between ulcerative colitis (UC) and Crohn's disease (CD) with active inflammation--is a new addition to existing methods with a higher stated sensitivity and specificity.	22229803
Gastrointestinal inflammation	Altered Intercellular Communication	We suggest that fecal calprotectin may be a marker for subclinical intestinal inflammation in AS and should be measured after stopping NSAIDs, but further endoscopic studies are needed.	22229862
Refractory anemias, Inflammation	Altered Intercellular Communication	These findings suggest that HDL is significantly altered in the setting of chronic inflammation in active RA, with resultant loss of its antiinflammatory function.	22231638
Heart failure, Myocarditis	Altered Intercellular Communication	High-Mobility-Group Box 1 (HMGB1) has been established as an important mediator of myocardial inflammation and associated with progression of heart failure (HF).	22231645
Cessation of life, Inflammation	Altered Intercellular Communication	These findings might provide a molecular basis for new strategies targeting cell death pathways in apoptosis-resistant neutrophils during systemic inflammation.	22231730
Inflammation, Atherosclerosis	Altered Intercellular Communication	Chlamydophila pneumoniae phospholipase D (CpPLD) drives Th17 inflammation in human atherosclerosis.	22232679
Dermatitis, Atopic, Psoriasis, Dermatitis	Altered Intercellular Communication	Psoriasis and atopic dermatitis are associated with quantitative and qualitative changes of peripheral NK cells, mostly shared by both diseases, supporting a common process implicating these innate effectors in skin inflammation.	22233261
ARCN1 gene, Inflammation, Airway structure, Chronic Obstructive Airway Disease, Lung diseases	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a lung disease characterized with limitation of airflow that is not completely reversible, progressive deterioration of airways and systemic inflammation.	22233302
Inflammation, Asthma, Dermatitis, Atopic	Altered Intercellular Communication	The IL-33 induces T helper 2-type inflammatory responses and is considered to play a crucial rule in allergic inflammations, such as asthma and atopic dermatitis.	22233535
Inflammation, Pancreatitis, Necrosis	Altered Intercellular Communication	Both the ARFI-VTQ and eSie touch elasticity imaging techniques may be successfully adopted in order to diagnose acute pancreatitis, to assess extent of inflammation (whether focal or diffuse), to assess peripancreatic edema, to identify presence of necrotic areas and early pseudocyst formation, to early diagnose acute recurrent attacks and to monitor patient's response to treatment.	22233945
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Severity of inflammation may be a risk factor for negative outcome in non-operative therapy of appendicitis.	22234068
Inflammation, Anastomosis - action, Fibrosis Assessment	Altered Intercellular Communication	Anastomotic stenosis after PG is observed in some patients after approximately 1 to 2 postoperative weeks and is attributed to acute inflammation and fibrosis around the anastomosis.	22234082
Inflammation, Atherosclerosis	Altered Intercellular Communication	Based on its multiple roles in inflammation, atherogenesis and glucose homeostasis, we hypothesised that activin A could be related to coronary atherosclerosis in T2DM.	22234949
Inflammation, Fever, CTCAE, Arthralgia, Granulomatous, Malaise, Weight decreased, Myalgia, CTCAE 5	Altered Intercellular Communication	arthralgias, myalgia, malaise, fever, and weight loss), 3) detection of autoantibodies in patients' sera, 4) histological evidence of chronic inflammation and/or granulomatous reaction to foreign body.	22235042
Inflammation, Heart failure	Altered Intercellular Communication	Markers of inflammation, metabolic risk factors, and incident heart failure in American Indians: the Strong Heart Study.	22235819
Inflammation, Metabolic Syndrome X, Diabetes Mellitus, Heart failure, Obesity, MS gene	Altered Intercellular Communication	Inflammation may play a role in increased risk of heart failure (HF) that is associated with obesity, metabolic syndrome (MS), and diabetes.	22235819
Inflammation	Altered Intercellular Communication	This early microvascular impairment might be hypothesized as the consequence of prolonged and sustained systemic inflammation and might explain the increased cardiovascular risk conferred by Pso.	22236480
Asthma, allergic inflammation	Altered Intercellular Communication	Omalizumab may inhibit allergic inflammation and could contribute to decreasing airway remodeling in patients with asthma.	22236804
Airway structure	Altered Intercellular Communication	These findings suggest that omalizumab reduced airway wall thickness and airway inflammation.	22236804
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Elevated serum uric acid is not associated with endothelial dysfunction among healthy adults, but is inversely related to EID and EC MnSOD, and positively related to systemic inflammation.	22237152
Inflammation, Thrombosis, Endothelial dysfunction	Altered Intercellular Communication	Previous studies suggest that air pollution is related to thrombosis, inflammation, and endothelial dysfunction.	22237295
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Role of inflammation in early atrial fibrillation recurrence.	22237586
Inflammation	Altered Intercellular Communication	Baseline log(2) interleukin (IL)-6 [adjusted hazard ratio (HR) 1.3, 95% confidence interval (CI) 1.0-1.7, P= 0.02] and present or previous smoking (adjusted HR 3.6, 95% CI 1.2-10.9, P= 0.03) were independently associated with early AF recurrence, suggesting that inflammation played an important role in early recurrences.	22237586
Left Ventricular Hypertrophy, Inflammation, Hypertrophy, Uremia, Hypertensive (finding)	Altered Intercellular Communication	Markers of inflammation have previously been related to left ventricular (LV) hypertrophy (LVH) in uremic and hypertensive patients.	22237633
Inflammation	Altered Intercellular Communication	Further studies are motivated to investigate a pathogenetic role of inflammation for abnormal LV geometry and function.	22237633
vascular inflammations	Altered Intercellular Communication	Immunostaining against T-cells (CD3) and monocytes and macrophages (CD68) was used to explore a putative association between TGF-b and BMP signaling and vascular inflammation.	22237716
Vasculitis, Dental Plaque	Altered Intercellular Communication	No significant relationships were found between Smad phosphorylation and vessel wall inflammation or plaque vulnerability.	22237716
Proteinuria, Tubular atrophy, Interstitial inflammation	Altered Intercellular Communication	Increased epithelial syndecan-1 in allografts correlated with low proteinuria and serum creatinine, less interstitial inflammation, less tubular atrophy, and prolonged allograft survival.	22237752
Myelitis, Unspecified visual loss	Altered Intercellular Communication	The case of the Marquis de Causan (1804): an early account of visual loss associated with spinal cord inflammation.	22237820
Myelitis, Unspecified visual loss	Altered Intercellular Communication	Portal's report, which fascinated some of the most renowned 19th century pioneers in the field of neurology but fell into oblivion later, represents the first account of visual loss in a patient with spinal cord inflammation but no brain pathology in the Western literature known so far--published more than 60 years prior to Thomas Clifford Allbutt's much cited note on a patient with myelitis and a "sympathetic eye disorder".	22237820
Inflammation, Dental Plaque, atherosclerotic	Altered Intercellular Communication	Inflammation within atherosclerotic plaques is associated with instability of the plaque and future cardiovascular events.	22239891
Inflammation, Failure (biologic function), Atherosclerosis	Altered Intercellular Communication	Differences in lesion extraction technique, lesion size, the degree of inflammation, and imaging coregistration techniques may have been responsible for the failure to observe the strong correlations with vascular FDG uptake observed in previous studies of the carotid artery and in several animal models of atherosclerosis.	22239891
Inflammation, Hypersensitivity, Atherosclerosis	Altered Intercellular Communication	Other important morphological features such as fibrin accumulation, excessive inflammation (hypersensitivity), and in-stent atherosclerosis were characterized by OFDI; however, the similarly dark appearance of these tissues did not allow for direct visual discrimination.	22239896
Tumor necrosis, Inflammation, Adenocarcinoma Of Esophagus, Neoplasms	Altered Intercellular Communication	The relationship between tumour necrosis, tumour proliferation, local and systemic inflammation, microvessel density and survival in patients undergoing potentially curative resection of oesophageal adenocarcinoma.	22240784
Dysautonomia	Altered Intercellular Communication	Depending on the disease burden, MG patients may experience chronic dysregulation of both the hormonal stress axis and the immune system, consequently, aggravating the disease itself but also leading to secondary psychopathological abnormalities.	22240858
Inflammation, Liver Failure	Altered Intercellular Communication	Neither signs of hepatic or renal failure nor of inflammation or impaired acid-base balance allowed a prediction of survival in these patients.	22241001
Carotid Atherosclerosis, Inflammation, Hypotension, Orthostatic	Altered Intercellular Communication	In older nondiabetic adults only orthostatic hypotension seems to independently correlate with increased carotid atherosclerosis and systemic inflammation.	22241141
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Intestinal epithelial barrier disruption is a feature of inflammatory bowel disease (IBD), but whether barrier disruption precedes or merely accompanies inflammation remains controversial.	22241861
Inflammation, Ulcerative Colitis, Colitis	Altered Intercellular Communication	Our results revealed that lipid rafts were disrupted in IFN-g-treated cells, in the ilea of mice with subclinical colitis, and in UC patients with quiescent inflammation.	22241861
Inflammation, Rheumatic Fever	Altered Intercellular Communication	Rabbits received intra-articular injections of lipopolysaccharides (LPS) to induce inflammation that mimic rheumatic arthritis.	22242954
Inflammation	Altered Intercellular Communication	We examined and compared the bioceramic and control groups to see if bioceramic was capable of relieving inflammation in the joints by subtracting the final and initial uptake amount of FDG (max SUV).	22242954
Inflammation, S100A4 protein, human	Altered Intercellular Communication	Chronic inflammation, like in BE, markedly increase the risk of malignant transformation.	22243485
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Modulation of intestinal microbiota by non-digestible carbohydrates may reduce inflammation in inflammatory bowel disease (IBD).	22243836
Acute and chronic inflammation, Colitis	Altered Intercellular Communication	Colitis was significantly reduced in all FOS-fed rats compared to the control diet, whereas inulin decreased chronic intestinal inflammation in only half the number of animals.	22243836
Acute and chronic inflammation, Clostridium difficile colitis, Family Peptostreptococcaceae	Altered Intercellular Communication	In conclusion, FOS increased the abundance of Bifidobacterium spp., whereas both fructans reduced Clostridium cluster XI and C. difficile toxin gene expression, correlating with a reduction of chronic intestinal inflammation.	22243836
Inflammation, Hyperplastic Polyp, Observation Method - Coagulation	Altered Intercellular Communication	Microparticles (MP) are small membrane vesicles, released from activated, damaged and apoptotic endothelial cells (EMP) or platelets (PMP) that may actively modulate inflammation, coagulation and vascular function.	22245039
Malignant neoplasm of testis, Inflammation	Altered Intercellular Communication	It is important to distinguish this activity from other possible malignant and benign conditions such as lymph node activity, testicular cancer, metastatic disease activity, inflammation and urine skin contamination artefact.	22245311
Inflammation, Cardiovascular Diseases, Diabetes Mellitus, Obesity, Disease	Altered Intercellular Communication	APOE4) or involved in pathologic processes contributing to the disorder, including inflammation, diabetes, obesity and cardiovascular disease.	22245343
Refractory anemias, Inflammation	Altered Intercellular Communication	In RA, our results show a greater relative abundance of proteins related to complement activation, inflammation and the immune response, such as the major matrix metalloproteinases and several neutrophil-related proteins.	22245418
Gastroesophageal reflux disease, Primary malignant neoplasm, Adenocarcinoma Of Esophagus	Altered Intercellular Communication	Gastroesophageal reflux disease is a strong risk factor for esophageal adenocarcinoma, but it is not clear whether the mucosal inflammation that develops in patients with reflux disease promotes this cancer.	22245963
Inflammation, Adenocarcinoma Of Esophagus	Altered Intercellular Communication	Inflammation therefore might be an important factor in the progression from reflux to esophageal adenocarcinoma.	22245963
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	Treatment with intraperitoneal recombinant human (rh) ACE2 (2 mg/kg) for 21 days improved survival, exercise capacity, and lung function and decreased lung inflammation and fibrosis in male BLM-WT mice.	22246130
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Adipokines and systemic inflammation in weight-losing lung cancer patients.	22246553
Inflammation, Non-Small Cell Lung Carcinoma, Advanced Lung Non-Small Cell Squamous Carcinoma	Altered Intercellular Communication	The objective of the present study was to investigate the relationship of adipokines and systemic inflammation in weight-losing advanced-stage non-small-cell lung cancer (NSCLC) patients.	22246553
Inflammation	Altered Intercellular Communication	However, there was no correlation between adipokines and markers of systemic inflammation.	22246553
Inflammation, Cachexia	Altered Intercellular Communication	These results revealed a lack of association between adipokine levels and systemic inflammation with cancer cachexia.	22246553
Apolipoproteins B, vascular inflammations	Altered Intercellular Communication	Apolipoprotein B (ApoB) directly reflects the number of plasma atherogenic lipoproteins, and may play a major role in vascular inflammation.	22246850
Inflammation, Fibrosis Assessment, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	However, analyses of mice receiving bleomycin (BLM) as a model of IPF established the importance of preceding inflammation for the formation of fibrosis.	22246863
Malignant Lesion	Altered Intercellular Communication	Benign lesions comprised 102 (85.7%) cases, malignant lesions comprised 14 (11.8%) cases and inflammation/abscess was found in 3 (2.5%) cases.	22246926
Inflammation, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	The CA of histology- and OCT-based judgments suggests that the diagnostic process may be characterized in terms of two stochastically independent underlying ("latent") variables, the first of them reflecting the definiteness with which CIN classes are identified, the second reflecting a bias towards diagnosing inflammation on the side of the OCT-based judgments.	22246983
Inflammation	Altered Intercellular Communication	This finding is supported by the results of LDAs, where histology and OCT categorizations differ in particular with respect to the positions of inflammation and CIN1.	22246983
Inflammation, Meningitis	Altered Intercellular Communication	Symptoms of cerebral involvement or signs of systemic inflammation were rare in children with LM compared to children non-Lyme aseptic meningitis.	22247243
Inflammation, destruction joint, Rheumatoid Arthritis	Altered Intercellular Communication	IgG glycosylation changes and MBL2 polymorphisms: associations with markers of systemic inflammation and joint destruction in rheumatoid arthritis.	22247351
Refractory anemias, Inflammation, destruction joint, Rheumatoid Arthritis	Altered Intercellular Communication	To examine whether IgG glycosylation changes and MBL2 genotypes are associated with systemic inflammation and joint destruction in rheumatoid arthritis (RA).	22247351
Inflammation, Tumor necrosis	Altered Intercellular Communication	Systemic inflammation was assessed by serum levels of C-reactive protein (CRP), interleukin 6 (IL-6), and tumor necrosis factor-a (TNF-a).	22247351
Refractory anemias	Altered Intercellular Communication	Our results suggest that inflammation-associated decreased galactosylation of IgG combined with high expression MBL2 genotypes are involved in the pathophysiology of RA.	22247351
Interstitial inflammation	Altered Intercellular Communication	Interstitial inflammation was less severe in patients with PTU-induced AAV (p < 0.05).	22247359
nervous system disorder, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) brain shows an ongoing inflammatory condition and non-steroidal anti-inflammatories diminish the risk of suffering the neurologic disease.	22248049
Inflammation, Dyslipidemias	Altered Intercellular Communication	Hemodialysis patients had increased protein OS and associations of inflammation and dyslipidemia were also observed in these dialysis groups.	22248198
Calcified (qualifier), Inflammation	Altered Intercellular Communication	Klotho null mice are a model for premature aging and exhibit calcific nodules in the aortic valve hinge-region, but do not exhibit leaflet thickening, ECM disorganization, or inflammation.	22248532
Inflammation, FAM126A gene, TNM Staging System, Hypertension, CTCAE, Liver Cirrhosis	Altered Intercellular Communication	Decreased liver size and indirect evidence of more severe portal hypertension and earlier TNM stage compared with HBV monoinfection indicate that HDV infection causes HCC in a different way, possibly indirectly by inducing inflammation and cirrhosis.	22249087
Colitis, Ulcer	Altered Intercellular Communication	Ileocolonoscopy revealed colonic inflammation with ulcers and pseudopolyps.	22249306
Inflammation, Illness (finding), Traumatic injury	Altered Intercellular Communication	Heart rate variability (HRV) is a sensitive marker of altered sympathetic-parasympathetic function and is reduced in inflammation, illness, and trauma.	22249435
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Obstructive sleep apnea has been associated with generalized inflammation and nervous-endocrine, cardiovascular, and other systemic biophysiologic phenomena.	22249630
Airway structure	Altered Intercellular Communication	Low serum 25-hydroxyvitamin D (25-[OH]D) levels have been associated with lower FEV(1), impaired immunologic control, and increased airway inflammation.	22250141
Inflammation, Primary malignant neoplasm, FAM126A gene	Altered Intercellular Communication	HCC may be an unusual cancer affected by continuous inflammation that can lead to consistent upregulation of transforming growth factor-beta (TGF-beta).	22251470
Inflammation, Chronic cholecystitis, Nesidioblastosis	Altered Intercellular Communication	Endocrine cell hyperplasia may be related to longstanding inflammation as in chronic cholecystitis and all secreted hormones from the described ECs can support pathologic process in the choledochus, i.e.	22251519
Muscle Contraction, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	inflammation, increased mucus secretion, fibrosis, muscle contraction, etc.	22251519
Inflammation, Chronic cholecystitis, Nesidioblastosis	Altered Intercellular Communication	Endocrine cell hyperplasia may be related to longstanding inflammation as in chronic cholecystitis and all secreted hormones from the described ECs can support pathologic process in the choledochus, i.e.	22251519
Inflammation, Gallbladder Carcinoma	Altered Intercellular Communication	Chronic inflammation is a risk factor for gallbladder carcinoma.	22251522
Inflammation, Gallbladder Carcinoma	Altered Intercellular Communication	The molecular mechanisms linking inflammation and gallbladder carcinogenesis are incompletely understood.	22251522
Contracture of bladder neck, Urethral Stenosis, Prostate, prostatitis	Altered Intercellular Communication	Impact of asymptomatic prostatitis on re-operations due to urethral stricture or bladder neck contracture developed after TUR-P. To evaluate the relationship between pathologically proven prostatic inflammation (PI) and re-operation rates due to urethral stricture (US) or bladder neck contracture (BNC) after transurethral resection of prostate (TUR-P).	22252218
prostatitis	Altered Intercellular Communication	In logistic regression analysis, duration of initial TUR-P and PI were found to be independent risk factors for development of BNC or US after TUR-P. Prostatic inflammation on TUR-P pathology is an independent variable affecting the development of US or BNC.	22252218
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	Over half of chronic rhinosinusitis with nasal polyps (CRSwNP) patients in China show noneosinophilic inflammation.	22252861
Aneurysmal, Inflammation	Altered Intercellular Communication	We hypothesize that inflammation of the gland had weakened the wall of the adjacent facial vein, causing aneurysmal dilatation.	22253006
Inflammatory abnormality of the eye, Blepharoconjunctivitis	Altered Intercellular Communication	To compare the efficacy and safety of loteprednol etabonate 0.5%/tobramycin 0.3% (LE/T) and dexamethasone 0.1%/tobramycin 0.3% (DM/T) ophthalmic suspensions in a Chinese population with ocular inflammation associated with blepharokeratoconjunctivitis (BKC).	22256909
Chronic suppurative inflammation, Actinomycosis	Altered Intercellular Communication	After nephrectomy, sulfur granules with chronic suppurative inflammation were seen microscopically, and the histopathological diagnosis was renal actinomycosis.	22257547
Traumatic injury	Altered Intercellular Communication	In 1997, 43% of the total elbow arthroplasties were associated with trauma and 48%, with inflammatory conditions.	22257996
Communicable Diseases, Inflammation	Altered Intercellular Communication	Inflammation and infection are associated with premature birth and with activation of the fetal immune system.	22258123
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Cases of IA tend to have more histologically active inflammation except for a relatively normal erythrocyte sedimentation rate, localised lesions and milder intimal fibrosis than cases of TA.	22259176
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Deficient Food Intake	Altered Intercellular Communication	Whereas nutrition deficits are recognized as an expression of systemic inflammation in the elderly with diagnosed chronic obstructive pulmonary disease (COPD), if they occur in symptomatic elderly smokers, unfulfilled COPD criteria are not confirmed.	22259244
Inflammation, Cardiac complication, Depression, CTCAE, Chronic Kidney Diseases	Altered Intercellular Communication	Serum T3 depression predicts a negative outcome in chronic kidney disease (CKD) patients and may be associated with cardiovascular complications or chronic inflammation.	22260378
Inflammation	Altered Intercellular Communication	High C3 may be considered a hallmark of inflammation and C3 revealed the highest predictive value for response to anti-TNF.	22260811
Inflammation, Periodontal Route of Administration	Altered Intercellular Communication	Participants had widespread periodontal inflammation but limited periodontal destruction.	22261235
Inflammation, Periodontal Route of Administration	Altered Intercellular Communication	GCF cytokine levels were not strongly associated with serum cytokine levels in pregnant women with widespread periodontal inflammation but limited periodontal destruction.	22261235
Inflammation, Ulcerative Colitis, Mucosal ulcer, Chronic inflammatory disorder	Altered Intercellular Communication	Ulcerative colitis (UC) is a chronic inflammatory disease characterized by recurrent inflammation and ulcerations of colonic mucosa and an inappropriate and delayed healing.	22261534
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Correlation analysis was also performed between ADA and other inflammation markers of UC.	22261534
Ulcerative Colitis	Altered Intercellular Communication	Although ADA has been shown to increase in several inflammatory conditions, there are no literature data indicating an alteration in UC.	22261534
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Local inflammation in the brain following stroke is thought to enhance damage.	22261543
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Chronic inflammation and decreased frequency of regulatory T cells (Tregs) in visceral adipose tissue contribute to the propagation of insulin resistance to diabetes mellitus.	22262764
Inflammation, Adherence (attribute)	Altered Intercellular Communication	Because platelet adherence to leukocytes allows for both firm adhesion to endothelial cells and augmented transcellular conversion of leukotrienes, a disturbance in platelet-leukocyte interactions may be partly responsible for the respiratory tissue inflammation and the overproduction of cysLTs that characterize AERD.	22262771
Refractory anemias, Inflammation	Altered Intercellular Communication	COMP-C3b levels in RA decrease during TNF-a inhibition differently from those of CRP, suggesting that formation of COMP-C3b relates to disease features not reflected by general inflammation measures.	22264230
Pulmonary Emphysema	Altered Intercellular Communication	Targeted deletion of Jun/AP-1 in alveolar epithelial cells causes progressive emphysema and worsens cigarette smoke-induced lung inflammation.	22265050
Chronic Obstructive Airway Disease, Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	In this study, we report decreased expression levels of c-Jun mRNA and protein in the lung tissues of patients with advanced chronic obstructive pulmonary disease, and the genetic deletion of c-Jun specifically in alveolar epithelial cells causes progressive emphysema with lung inflammation and alveolar air space enlargement, which are cardinal features of emphysema.	22265050
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	These results demonstrate that the c-Jun/activator protein 1 pathway is critical for maintaining lung alveolar cell homeostasis and that loss of its expression can contribute to lung inflammation and progressive emphysema.	22265050
Inflammation, Necrosis	Altered Intercellular Communication	The severe peripheral flap inflammation resulted in stromal necrosis that was unresponsive to intensive topical steroid but improved rapidly on oral prednisone.	22265184
Inflammation	Altered Intercellular Communication	Two important protective factors for low-grade inflammation may be physical activity (PA) and fitness.	22265274
Inflammation	Altered Intercellular Communication	High PA in adolescence may play an indirect role on lessening low-grade inflammation through improvements in fitness.	22265274
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	There is evidence that chronic inflammation may promote atherosclerotic disease.	22265583
Asthma	Altered Intercellular Communication	Impact of add-on pranlukast in stable asthma; the additive effect on peripheral airway inflammation.	22265857
Airway structure, Asthma	Altered Intercellular Communication	The importance of airway inflammation has been highlighted in the pathophysiology of asthma.	22265857
Airway structure	Altered Intercellular Communication	Even in controlled asthmatics treated with inhaled corticosteroid (ICS), residual airway inflammation is reported.	22265857
Airway structure, Asthma	Altered Intercellular Communication	The addition of oral pranlukast to ICS or ICS + LABA therapy may improve asthma control with reducing distal airway inflammation.	22265857
Kidney Failure, Chronic, Chronic inflammation, Complications of Diabetes Mellitus, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Levels of proinflammatory cytokines associate with risk for developing type 2 diabetes but whether chronic inflammation contributes to the development of diabetic complications, such as ESRD, is unknown.	22266663
Inflammation, Musculoskeletal Pain, Aortic Stiffness	Altered Intercellular Communication	Polymyalgia rheumatica is associated with increased aortic stiffness which may improve upon reduction of systemic inflammation induced by treatment with glucocorticoids.	22267333
Inflammation, Atherosclerosis	Altered Intercellular Communication	It is not clear, however, whether periodontal inflammation may be associated with increased markers of atherosclerosis in these patients.	22267416
Arterial Stiffness, Inflammation, square decimeter	Altered Intercellular Communication	Periodontal inflammation in patients with DM2 seems to be associated with increased IMT and BP, but not with greater arterial stiffness.	22267416
Immunologic Deficiency Syndromes, Inflammation	Altered Intercellular Communication	In ART-naive patients, severe immune deficiency but not inflammation could be an early risk factor for altered insulin sensitivity.	22267473
Inflammation, Candidiasis	Altered Intercellular Communication	Oral candidiasis is often accompanied by severe inflammation, resulting in a decline in the quality of life of immunosuppressed individuals and elderly people.	22267663
Inflammation	Altered Intercellular Communication	Enhanced inflammation could contribute to persistent obstruction by impairing pulmonary vascular cell function in CTEPH.	22267767
Asthma	Altered Intercellular Communication	ASMC syndecan-4 production during Th1 inflammatory conditions may regulate chemokine activity and mast cell recruitment to the ASM in asthma.	22268118
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice.	22268122
Hyperactive behavior, Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	Genetic reduction of Stat3 hyperactivity in gp130(F/F):Stat3(-/+) mice prevented lung inflammation and excessive protease activity; however, emphysema still developed.	22268122
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	In support of these findings, Stat3 activation levels in human lung tissue correlated with the extent of pulmonary inflammation but not airflow obstruction in COPD.	22268122
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	Collectively, our data suggest that IL-6 promotes emphysema via upregulation of Stat3-independent apoptosis, whereas IL-6 induction of lung inflammation occurs via Stat3.	22268122
ARCN1 gene, Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	We propose that while discrete targeting of Stat3 may alleviate pulmonary inflammation, global targeting of IL-6 potentially represents a therapeutically advantageous approach to combat COPD phenotypes where emphysema predominates.	22268122
Epithelial Damage, Inflammation	Altered Intercellular Communication	CC is characterized histopathologically by an increase in the thickness of the subepithelial collagen layer to at least 10 mm, epithelial damage, and chronic inflammation of the lamina propria.	22269295
Amyotrophic Lateral Sclerosis, Inflammation, MS gene, Nerve Degeneration	Altered Intercellular Communication	Concurrent multiple sclerosis and amyotrophic lateral sclerosis: where inflammation and neurodegeneration meet?	22269588
Airway structure, Asthma, Arthritis, Infectious	Altered Intercellular Communication	Blood NKT cells decreased during infection-associated asthma exacerbation and were inversely associated with eosinophilic airway inflammation, suggesting that blood NKT cells might be mobilized to the airways and lungs during asthma exacerbation in humans.	22269676
Parkinson Disease, "Alzheimers Disease", palladium, Data types - Address	Altered Intercellular Communication	Monoamine oxidase-B (Mao-B) catalysing the breakdown of the neurotransmitter dopamine, is known to be involved in the pathophysiology of Parkinson's (PD) and Alzheimer's disease (AD).	22270014
Dissection of carotid artery, Labor (Childbirth), Traumatic injury	Altered Intercellular Communication	Intimal injury related to the Valsalva maneuver during labor as well as hemodynamic and hormonal changes related to pregnancy are presumed causes of peripartum spontaneous carotid artery dissection.	22270449
Hematoma, Subdural, Inflammation	Altered Intercellular Communication	We hypothesise that dural mast cells may contribute to neurogenic inflammation and the clinical features of subdural haemorrhage.	22270653
Inflammation	Altered Intercellular Communication	Although periportal and lobular necroinflammation vanished, portal inflammation persisted in 66%.	22271347
Inflammation	Altered Intercellular Communication	Despite ductular proliferation vanishing and lobular zonation restoration, portal inflammation and sinusoidal capillarization may not regress after viral eradication.	22271347
Inflammation, Fibrosis Assessment, Injury of liver	Altered Intercellular Communication	The deficiency of HIFs in macrophages did not affect liver injury or inflammation after BDL but reduced PDGF-B mRNA and protein, suggesting that HIF activation in macrophages may promote fibrosis by regulating the production of PDGF-B.	22271822
Granulomatosis with polyangiitis, Orbital Pseudotumor	Altered Intercellular Communication	Treatment of orbital inflammation with rituximab in Wegener's granulomatosis.	22272561
Orbital Pseudotumor	Altered Intercellular Communication	Ten WG patients with orbital inflammation were included in this case-series.	22272561
Orbital Pseudotumor	Altered Intercellular Communication	All patients had orbital inflammation demonstrated by CT-scan before treatment (3 had bilateral and 7 unilateral orbital involvement).	22272561
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	In Alzheimer's disease (AD) brain, the levels of these neurosteroids are known to be altered compared to age-matched non-demented controls.	22272612
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Pharmacological inhibition of PKR in APPswePS1dE9 mice transiently prevents inflammation at 12 months of age but increases Ab42 levels in the late stages of the Alzheimer's disease.	22272616
Inflammation, Data types - Address	Altered Intercellular Communication	Whether or not inflammation represents a possible cause of AD or occurs as a consequence of the disease process, or, alternatively, whether the inflammatory response might be beneficial to slow the disease progression remains to be elucidated.	22272623
Inflammation, Data types - Address	Altered Intercellular Communication	An important piece of evidence supporting a pathophysiologic role for inflammation in AD is the number of inflammatory mediators that have been found to be differentially regulated in AD patients, and specific ones may provide utility as part of a biomarker panel to not only aid early AD diagnosis, but follow its progression.	22272623
Inflammation, Carcinogenesis	Altered Intercellular Communication	One of COX-2 main metabolites is prostaglandin E2 (PGE2), which is involved both in inflammation and carcinogenesis.	22272632
Low Back Pain, Inflammation, LAURIN-SANDROW SYNDROME, Neurogenic claudication	Altered Intercellular Communication	Reports on LSS treatment with ESIs have not differentiated between neurogenic claudication, which is believed to result from nerve root compression, and lumbar radicular pain, thought to be caused by inflammation.	22272730
Inflammation	Altered Intercellular Communication	CT-guided biopsy revealed chronic inflammation of those pulmonary nodules, and laboratory studies disclosed elevated serum levels of carbohydrate antigen 19-9 (CA 19-9) and CA 125.	22273501
Inflammation, Erosion lesion, Rheumatoid Arthritis	Altered Intercellular Communication	Inter- and intra-observer agreement of high-resolution ultrasonography and power Doppler in assessment of joint inflammation and bone erosions in patients with rheumatoid arthritis.	22274131
Inflammation, Erosion of bone	Altered Intercellular Communication	Five members of the "Escuela de Ecografia del Colegio Mexicano de Reumatologia" tested their inter- and intra-observer reliabilities in the assessment of basic sonographic findings of joint inflammation and bone erosion.	22274131
Inflammation, Hyperplasia, Spondylitis	Altered Intercellular Communication	Evidence indicates that the hyperplasia and inflammation of synovial tissues are significantly related to the pathogenic process of ankylosing spondylitis (AS).	22274560
Irritation - emotion, Inflammation	Altered Intercellular Communication	Gingival irritation and inflammation due to poor oral hygiene were the major precipitating factors.	22274762
Inflammation, Arthritis	Altered Intercellular Communication	Link between traditional cardiovascular risk factors and inflammation in patients with early arthritis: results from a French multicenter cohort.	22275176
Inflammation, Arthritis, Each (qualifier value)	Altered Intercellular Communication	To compare the characteristics of traditional cardiovascular risk factors for untreated patients with early arthritis (EA) and healthy subjects, and to look for a link between cardiovascular risk factors and inflammation in EA patients.	22275176
Inflammation, Chronic disease	Altered Intercellular Communication	Controlled inflammation has become a central focus in chronic disease therapeutics.	22276585
Inflammation	Altered Intercellular Communication	Exaggerated inflammation is a common factor that contributes to matrix destruction, cellular senescence, and nonhealing in a variety of disease processes.	22276585
Inflammation	Altered Intercellular Communication	Efforts at controlling inflammation have traditionally concentrated on systemic antagonists to inflammation such as nonsteroidal anti-inflammatory agents.	22276585
Inflammation, Necrosis	Altered Intercellular Communication	Statistical correlation was evaluated for tumour histotype, mitotic count (MC), nuclear grade (NG), necrosis, lymphoid response (grade of inflammation) and desmoplasia with regard to survival.	22276610
Inflammation, Hypersensitivity, Diverticular Diseases	Altered Intercellular Communication	Visceral hypersensitivity in symptomatic diverticular disease and the role of neuropeptides and low grade inflammation.	22276853
Inflammation, Hypersensitivity, Diverticular Diseases	Altered Intercellular Communication	Patients with symptomatic diverticular disease exhibit visceral hypersensitivity, and this may be mediated by ongoing low grade inflammation and upregulation of tachykinins.	22276853
Inflammation, Terminal Osseous Dysplasia and Pigmentary Defects, Hypertension, CTCAE	Altered Intercellular Communication	Inflammation is a pathogenic factor for target-organ damage (TOD) in hypertension.	22277919
Inflammation	Altered Intercellular Communication	Inflammatory parameters are significantly and independently associated with UAE in prehypertensive subjects, suggesting that inflammation may be a pathogenic factor for the early vascular or TOD in these individuals.	22277919
Adrenocorticotropic hormone (ACTH) deficiency (disorder), Hashimoto Disease, Thyroid Crisis, Craniocerebral Trauma	Altered Intercellular Communication	Isolated adrenocorticotropic hormone deficiency associated with Hashimoto's disease and thyroid crisis triggered by head trauma.	22278027
Inflammation, Systemic disease, Disability, Damage, Arthritis, Psoriatic	Altered Intercellular Communication	Psoriatic arthritis is a chronic systemic disease in which patients develop persistent inflammation of the skin and joints, leading to disability and joint damage.	22278305
Inflammation, Neoplasms	Altered Intercellular Communication	The extracellular component hyaluronan (HA) plays an important role in regulatory processes such as inflammation, wound healing and tumour progression.	22278305
Inflammation	Altered Intercellular Communication	At any site of inflammation HA can be depolymerized to low-molecular weight fragments, which, in turn, induce an array of inflammatory mediators that can lead to chronic inflammation.	22278305
Inflammation, Hypertension, CTCAE, Endothelial dysfunction	Altered Intercellular Communication	In this Mongolian population, IR and elevated biomarkers of inflammation and endothelial dysfunction were related to hypertension and the coexistence of IR and elevated biomarkers of inflammation and endothelial dysfunction increased the risk of hypertension.	22278626
Sepsis, Inflammation, Communicable Diseases	Altered Intercellular Communication	Use of a weighted, automated analysis of the differential blood count to differentiate sepsis from non-infectious systemic inflammation: the intensive care infection score (ICIS).	22280231
Inflammation, Vitreous opacities	Altered Intercellular Communication	Immunocytochemical diagnosis as inflammation by vitrectomy cell blocks in patients with vitreous opacity.	22281090
Inflammation, Vitreous opacities	Altered Intercellular Communication	To describe the clinical and cytopathologic characteristics in patients with vitreous opacity of unknown cause or preceding inflammation, diagnosed cytopathologically as inflammation.	22281090
Inflammation, Vitreous opacities	Altered Intercellular Communication	Forty-three consecutive patients (61 eyes) who underwent vitrectomy for vitreous opacity of unknown cause or preceding inflammation and were diagnosed cytopathologically with inflammation at one institution in 6 years from 2005 to 2010.	22281090
Inflammation, Primary cerebral lymphoma, Vitreous opacities, Lymphoma	Altered Intercellular Communication	Inflammation was diagnosed in 2 patients with vitreous opacity who had a preceding onset of brain lymphoma or systemic lymphoma.	22281090
Inflammation, Vitreous opacities	Altered Intercellular Communication	The presence of macrophages, combined with small T lymphocytes, was a major sign in intravitreal inflammation, manifesting as vitreous opacity.	22281090
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Inflammation plays an important role in the pathophysiology of atherosclerosis and endothelial dysfunction, and occurs after percutaneous coronary intervention (PCI).	22281412
Mortality, Premature, Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Hyperadiponectinemia protects against premature death in metabolic syndrome model mice by inhibiting AKT signaling and chronic inflammation.	22281526
Inflammation, Impaired	Altered Intercellular Communication	We hypothesized that CAT scores at exacerbation relate to exacerbation severity as measured by exacerbation duration, lung function impairment, and systemic inflammation.	22281834
Inflammation, Endophthalmitis, CTCAE	Altered Intercellular Communication	There were three cases (0.3%) of endophthalmitis (inflammation of the internal coats of the eye).	22282278
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	In animal emphysema models, palovarotene reduced inflammation, promoted structural repair and functional improvement.	22282548
Uremia, Inflammation	Altered Intercellular Communication	These data suggest a potential link between the high levels of inflammation and cardiovascular mortality in uremia.	22282592
Malignant tumor of colon, Colorectal Carcinoma, Gastrointestinal inflammation	Altered Intercellular Communication	Because chronic intestinal inflammation is a risk factor for colorectal cancer, we hypothesized that genetic variants of inflammatory mediators, such as mannose-binding lectin 2 (MBL2), are associated with colon cancer susceptibility.	22282660
Refractory anemias, Inflammation, Rheumatoid Arthritis, Knee joint	Altered Intercellular Communication	To determine whether dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) evaluated using semi-automatic image processing software can accurately assess synovial inflammation in rheumatoid arthritis (RA) knee joints.	22283139
Refractory anemias, Inflammation	Altered Intercellular Communication	In 17 RA patients undergoing knee surgery, the average grade of histological synovial inflammation was determined from four biopsies obtained during surgery.	22283139
Inflammation	Altered Intercellular Communication	The IRE from the Quick ROI and the Precise ROI revealed high correlations to the grade of histological inflammation (Spearman's correlation coefficient (rho) = 0.70, p = 0.001 and rho = 0.74, p = 0.001, respectively).	22283139
Refractory anemias, Inflammation	Altered Intercellular Communication	DCE-MRI provides fast and accurate assessment of synovial inflammation in RA patients.	22283139
Sleep-Disordered Breathing, Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	An investigation into the relationship between sleep-disordered breathing, the metabolic syndrome, cardiovascular risk profiles, and inflammation between South Asians and Caucasians residing in the United Kingdom.	22283669
Sleep-Disordered Breathing, Inflammation	Altered Intercellular Communication	There was no independent association between SDB and markers of inflammation.	22283669
Pancreatic Neoplasm, Pancreatitis	Altered Intercellular Communication	K-ras mutations were extremely rare in pancreatic inflammation and other pancreatic tumors.	22284089
Autoimmune Diseases, Inflammation, Rheumatoid Factor	Altered Intercellular Communication	Protein citrullination is present in the rheumatoid synovium, presumably contributing to the perpetuation of chronic inflammation, in the presence of specific autoimmunity.	22284820
Refractory anemias, Inflammation	Altered Intercellular Communication	The presence of synovial CP was almost exclusive in RA compared with healthy synovium and correlated with the degree of local inflammation.	22284820
Inflammation	Altered Intercellular Communication	Synovial citrullination and PAD expression are dependent on local inflammation and targeted by glucocorticoids.	22284820
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The effects of fish oil supplementation on markers of inflammation in chronic kidney disease patients.	22285316
Inflammation, Traumatic injury	Altered Intercellular Communication	Early trauma and inflammation: role of familial factors in a study of twins.	22286843
Inflammation, Traumatic injury	Altered Intercellular Communication	Although early trauma (trauma in childhood) has been linked to adult inflammation and adult disease of inflammatory origin, it remains unknown whether this relationship is due to long-term consequences of early life stress or other familial factors.	22286843
Inflammation, Traumatic injury	Altered Intercellular Communication	The link between early trauma and inflammation is largely explained by familial factors shared by the twins because levels of inflammation were highest when both twins were exposed to trauma.	22286843
Inflammation	Altered Intercellular Communication	Clarification of familial factors associated with early stress and adult inflammation will be important to uncover correlates of stress and disease.	22286843
Tissue Adhesions	Altered Intercellular Communication	Inflammation/polyp recurrence, adhesions, and middle turbinate lateralization are causes of suboptimal outcomes following sinus surgery and lead to increased rates of revision.	22287304
Inflammation, polyps, Tissue Adhesions	Altered Intercellular Communication	Efficacy endpoints included assessment of inflammation, polyp formation, adhesions, and middle turbinate position.	22287304
Inflammation, Craniosynostosis	Altered Intercellular Communication	Persistence of respiratory viruses within the sinonasal mucosa is unlikely to be a cause of ongoing inflammation in CRS.	22287325
Inflammation, Paranasal Sinus Disorder	Altered Intercellular Communication	Collecting mucosal biopsies is invasive and creates additional inflammation, hampering a better understanding of nasal and sinus disease evolution and response to treatment.	22287327
Inflammation, Infection caused by Helicobacter pylori, Endothelium, Vascular	Altered Intercellular Communication	As default, Helicobacter pylori infection may cause systemic inflammation and vascular endothelial damage.	22287400
Inflammation, Helicobacter pylori, Prediabetes syndrome	Altered Intercellular Communication	Diabetics infected with Helicobacter pylori had significantly higher inflammation marker levels than non-infected patients (p<0.05).	22287400
Primary malignant neoplasm	Altered Intercellular Communication	Our findings suggested that ROS produced by neutrophils universally reflects the systemic inflammatory condition in cancer patients.	22287746
Liver carcinoma	Altered Intercellular Communication	Inflammation-based prognostic score for hepatocellular carcinoma patients on sorafenib treatment.	22287754
Malignant neoplasm of liver, FAM126A gene, Hypoalbuminemia	Altered Intercellular Communication	In 81 patients receiving sorafenib treatment for advanced HCC, we evaluated the prognostic significance of an inflammation-based prognostic score, the Glasgow prognostic score [evidenced by an elevated C-reactive protein level (>1.0 mg/dl) and hypoalbuminemia (<3.5 g/dl)] and compared it with Child-Pugh grade, Barcelona Clinic Liver Cancer staging system, Japan Integrated Staging (JIS) score, and the performance status by Cox-proportional analysis.	22287754
Inflammation, Granuloma, Tuberculosis, Fibrosis Assessment, Mycobacterium Infections	Altered Intercellular Communication	As opposed to tuberculosis the morphology of mycobacteriosis is more homogeneous and includes inflammation with epithelioid giant-cell granuloma and fibrosis, pneumogenic and bronchogenic cavernous cavities, mycobacterial endobronchitis.	22288163
Inflammation	Altered Intercellular Communication	[Influence of biological features of pathogens on maxillary sinus mucous chronic inflammation].	22288165
ARCN1 gene, Inflammation, Colonization, Necrosis, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic inflammation and reduced airways integrity in chronic obstructive pulmonary disease (COPD) potentially results from secondary necrosis as a result of impaired phagocytosis of apoptotic material by airway macrophages, and increased bacterial colonization.	22288725
ARCN1 gene, Inflammation, Exacerbation, Necrosis	Altered Intercellular Communication	Improved clearance of both apoptotic cells and bacteria in the airway may have a dual effect; reducing the risk of secondary necrosis and release of toxic cell contents that perpetuate inflammation as well as contributing to a reduction in the rate of exacerbations in COPD.	22288725
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is associated with systemic inflammation and oxidative stress.	22288943
Inflammation, Myeloid Leukemia, Chronic	Altered Intercellular Communication	N(e) -(carboxymethyl) lysine (CML), an advanced glycation end product (AGE) and the soluble decoy receptor, sRAGE, are exciting new molecules linked to oxidative stress and inflammation.	22288943
Inflammation, Myeloid Leukemia, Chronic	Altered Intercellular Communication	A lack of clear association between sRAGE, CML and systemic inflammation is furthermore evident.	22288943
Inflammation	Altered Intercellular Communication	Platelet-derived growth factor D (PDGF-D) plays an important role in angiogenesis, vessel remodeling, inflammation and repair in response to injury.	22289441
Communicable Diseases, Inflammation, Hepatitis C	Altered Intercellular Communication	Chronic inflammation from hepatitis C virus (HCV) infection is not considered to be one of these variables.	22289876
Inflammation, Liver Stiffness	Altered Intercellular Communication	In a multivariate analysis, inflammation (based on histologic analysis) and level of alanine aminotransferase (ALT) were associated with liver stiffness.	22289876
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	The chances of a patient having a level of stiffness that indicates cirrhosis increased with grade of inflammation and level of ALT.	22289876
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	By using a conservative 14.5-kPa cutoff for the diagnosis of cirrhosis, grade 3 inflammation had an odds ratio of 9.10 (95% confidence interval, 2.49-33.4).	22289876
Liver Stiffness	Altered Intercellular Communication	Inflammation should be considered a confounding variable in analysis of liver stiffness.	22289876
Inflammation, Sardinian language	Altered Intercellular Communication	A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation.	22291609
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Low sex hormone-binding globulin (SHBG) is associated with metabolic syndrome (MetS), but its relationship with inflammation is unclear.	22293276
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Low sex hormone-binding globulin (SHBG) is associated with metabolic syndrome (MetS), but its relationship with inflammation is unclear.	22293276
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	We investigated whether ELOVL polymorphisms are associated with adipose tissue fatty acids, serum lipids, inflammation and ultimately with nonfatal myocardial infarction (MI) in a Costa Rican population.	22293571
Inflammation, Hypercalcemia, CTCAE	Altered Intercellular Communication	Granulomatous inflammation of the skin and lymph nodes induced by intravenous or injectable silicone is a rare condition of hypercalcemia that is usually not within the scope of differential diagnosis.	22293885
Inflammation, Hypercalcemia, CTCAE	Altered Intercellular Communication	Topical applied liquid silicone by means of a focal ultrasound device induced extensive granulomatous inflammation of the skin and local lymph nodes, being the underlying cause for hypercalcemia in this case.	22293885
Necrotizing granulomatous inflammation	Altered Intercellular Communication	This is the first time that a transdermal silicone treatment has been reported to cause severe granulomatous tissue inflammation.	22293885
Airway structure	Altered Intercellular Communication	Airway inflammation is a critical regulator of disease outcome in RSV infected hosts.	22295065
Inflammation, Respiratory Syncytial Virus Infections, Bronchiolitis, Inflammatory disorder	Altered Intercellular Communication	Although "controlled" inflammation is required for virus clearance, aberrant and exaggerated inflammation during RSV infection results in development of inflammatory diseases like pneumonia and bronchiolitis.	22295065
Inflammation	Altered Intercellular Communication	Interleukin-1b (IL-1b) plays an important role in inflammation by orchestrating the pro-inflammatory response.	22295065
ARCN1 gene, Inflammation	Altered Intercellular Communication	25-HC production was enhanced in the airways of COPD patients and may play a role in neutrophilic inflammation.	22295989
Acute inflammation	Altered Intercellular Communication	Our data demonstrate that bacteria-related active inflammation results in a sharp increase of DMBT1 levels in enterocytes.	22296301
ARCN1 gene, Inflammation, Bronchial Obstruction	Altered Intercellular Communication	The results suggest that the relationships between reduced lung function, COPD and CVD are complex and not only linked to bronchial obstruction and low-grade systemic inflammation.	22296632
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Different MCAS presentations reflect elaboration of different mediators, some of which can induce inflammation and fibrosis.	22296862
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	Supplementation with Omega-3 fatty acids had no affect on platelet and endothelial activation or markers of inflammation in patients with peripheral arterial disease.	22296885
Inflammation, Caseous necrosis	Altered Intercellular Communication	The histopathology showed granulomatous inflammation with caseous necrosis.	22299474
Inflammation	Altered Intercellular Communication	Intimal thickness and cellularity, together with inflammation consisting of plasma cells were increased in C4d- as compared with C4d + (p < 0.05).	22300108
Tumor necrosis, Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Serum LCN2 levels were also compared with several indicators for metabolic syndrome, and with serum levels of interleukin (IL)-6 and tumour necrosis factor (TNF)-a, two markers of inflammation.	22300286
Inflammation, Psoriasis	Altered Intercellular Communication	Serum LCN2 levels are a general indicator for increased inflammation in the patients with psoriasis.	22300286
Conjunctivitis, Keratitis, Keratoconjunctivitis Sicca	Altered Intercellular Communication	Rarely, LP affects the conjunctiva, resulting in conjunctival inflammation, cicatrization and scarring of the subepithelium and cornea, causing keratitis and keratoconjunctivitis sicca.	22300330
ARCN1 gene, Tumor necrosis, Inflammation	Altered Intercellular Communication	This study sought to evaluate the systemic inflammatory profile associated with COPD and to assess the impact of tumor necrosis factor neutralization on systemic inflammation.	22300528
Inflammation, Necrosis	Altered Intercellular Communication	Because anti-tumor necrosis factor-alpha did not influence systemic inflammation, how to control the underlying pathology beyond symptom suppression remains unclear.	22300528
Inflammation, Transplant glomerulopathy	Altered Intercellular Communication	Microcirculation inflammation sum score predicted graft failure independently of time, C4d and transplant glomerulopathy.	22300601
Inflammation, Graft failure	Altered Intercellular Communication	Thus any degree of microcirculation inflammation in late kidney transplant biopsies strongly indicates presence of DSA and predicts progression to graft failure.	22300601
Inflammation	Altered Intercellular Communication	The dermis was notable for dilated eccrine ducts and absent inflammation.	22301047
Multiple polyps, Craniosynostosis, Tissue Adhesions, Acute inflammation, Chronic sinusitis	Altered Intercellular Communication	Endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS) may be compromised by postoperative inflammation, polyposis, and adhesions, often requiring subsequent intervention.	22301107
Inflammation	Altered Intercellular Communication	All of our patients had coexisting chronic illnesses associated with inflammation, as well as detectable HIV viral loads and CD4 count >200, suggesting a role for both HIV- and non-HIV-associated inflammation in HIV-HL pathogenesis in this population.	22302202
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Angiogenesis and inflammation are both important to the pathogenesis of malignancies.	22302227
Inflammation	Altered Intercellular Communication	Nuclear factor-kB (NF-kB) signaling plays critical roles in physiological and pathological processes such as responses to inflammation and oxidative stress.	22302838
Inflammation, Ischemic stroke, COL4A2 wt Allele	Altered Intercellular Communication	The results suggest that the relationships with inflammation for ischaemic stroke and ICH are different.	22303818
Inflammation, Swelling	Altered Intercellular Communication	Although eight-week old normal mice inoculated in the hind footpad developed no hind limb swelling with either virus, CHIKV-LR replicated in musculoskeletal tissues and caused detectable inflammation.	22305131
Inflammation, Dental Plaque	Altered Intercellular Communication	It has been suggested that these bacteria might contribute to inflammation and plaque instability.	22305832
Inflammation, Dental Plaque, Blood Circulation	Altered Intercellular Communication	We assumed that if periodontal bacteria induce inflammation of plaque, the bacteria would be released into the bloodstream when vulnerable plaque ruptures.	22305832
Inflammation, Dental Plaque	Altered Intercellular Communication	This raises the possibility that such bacteria are latently present in plaque and also suggests that these bacteria might have a role in plaque inflammation and instability.	22305832
vascular inflammations	Altered Intercellular Communication	Pentraxin-3 (PTX3) is an inflammatory marker thought to be more specific to vascular inflammation than C-reactive protein (CRP).	22305847
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Among persons with stable CHD, higher PTX3 concentrations were associated with increased risk for all-cause mortality, CV events, and incident HF independently of systemic inflammation.	22305847
Inflammation, Angina Pectoris	Altered Intercellular Communication	Platelet activation and inflammation have been recognized during AMI and stable angina (SA).	22306248
Inflammation, Fibrosis Assessment, Autoimmune Chronic Hepatitis, Hepatitis	Altered Intercellular Communication	Biopsy specimens showed not only centrizonal inflammation but also interface hepatitis and bridging fibrosis, which were characteristic of autoimmune hepatitis.	22306547
Inflammation	Altered Intercellular Communication	Surgical cardiac revascularization produces a high degree of systemic inflammation and the secretion of several cytokines.	22306617
Inflammation, Organ Dysfunction Scores, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Intensive postoperative inflammation may increase the incidence of postoperative atrial fibrillation and favor organ dysfunctions.	22306617
acetylglucosamine	Altered Intercellular Communication	Our results demonstrate that the absence of aGlcNAc triggers gastric tumorigenesis through inflammation-associated pathways in vivo.	22307328
Inflammation, Stomach Carcinoma, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Thus, aGlcNAc-terminated gastric mucin plays dual roles in preventing gastric cancer by inhibiting H. pylori infection and also suppressing tumor-promoting inflammation.	22307328
Inflammation, Atherosclerosis	Altered Intercellular Communication	Our results suggest the impact of PSGL-1 Met62Ile polymorphism on inflammation in advanced atherosclerosis.	22307784
Inflammation, Electrocardiogram: myocardial infarction (finding), Necrosis	Altered Intercellular Communication	Baseline NT-proBNP and biomarkers of inflammation and necrosis in patients with ST-segment elevation myocardial infarction: insights from the APEX-AMI trial.	22307842
Inflammation	Altered Intercellular Communication	This finding is consistent with pre-clinical and clinical research suggesting that systemic inflammation may influence NT-proBNP expression independently of myocardial stretch.	22307842
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Although inflammation appears to play a pivotal role in the pathophysiology of atrial fibrillation (AF), the source of inflammation is unknown.	22308085
Inflammation, Traumatic injury, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Whether TSP-2 may affect cardiac inflammation and injury, in particular during acute viral myocarditis, is completely unknown.	22308237
Inflammation, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Therefore, mortality, cardiac inflammation, and function were assessed in TSP-2-null (KO) and wild-type (WT) mice in human Coxsackie virus B3 (CVB3)-induced myocarditis.	22308237
Inflammation, Depressed mood, Traumatic injury, Cardiac dilatation	Altered Intercellular Communication	The absence of TSP-2 resulted in increased cardiac inflammation and injury at 14 days, which resulted in depressed systolic function [fractional shortening (FS); 34 +- 2.6 in WT vs. 24 +- 1.8 in KO mice, P< 0.05] and increased cardiac dilatation (end-diastolic dimensions, mm; 3.7 +- 0.09 in WT vs. 4.8 +- 0.06 in KO mice, P< 0.05) 35 days post-infection.	22308237
Communicable Diseases, Inflammation, Traumatic injury	Altered Intercellular Communication	Finally, overexpression of TSP-2 in WT hearts using cardiotropic vectors derived from adeno-associated virus serotype 9 (AAV9) inhibited cardiac inflammation and injury at 14 days and improved cardiac function at 35 days post-CVB3 infection when compared with control AAV9.	22308237
Inflammation, physiopathological, Traumatic injury, Acute myocarditis	Altered Intercellular Communication	TSP-2 has a protective role against cardiac inflammation, injury, and dysfunction in acute viral myocarditis.	22308237
Inflammation	Altered Intercellular Communication	A strong link between C5a, nucleosomes, and FSAP activity indicates that this new principle might be important in the regulation of inflammation.	22308306
Inflammation, Periodontitis, Gingival Hyperplasia	Altered Intercellular Communication	The incidence of chronic periodontitis in this age group is also high and the Ca antagonist medication in those individuals might substantially modify the clinical course of periodontal inflammation leading to gingival enlargement and hypertrophic pocket wall.	22308953
Achalasia, Inflammation, Neuropathy	Altered Intercellular Communication	The etiology of achalasia is believed to be the neuropathy associated with chronic inflammation of the nerve plexus, but the cause of plexus inflammation is unknown.	22309323
Superficial ulcer, Inflammation, Congenital hypotrichia, Fissure in skin, Ectoderm, Keratoderma, Palmoplantar, Fragile skin	Altered Intercellular Communication	Mutations in PKP1 may manifest with skin fragility and erosions, patches of scale crust on the trunk and limbs, peri-oral cracking and inflammation, hypotrichosis, palmoplantar keratoderma with painful fissuring and other somewhat variable ectodermal anomalies.	22309335
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP) is an acute-phase marker of systemic inflammation and considered an established risk marker for cardiovascular disease (CVD) in old age.	22309883
Necrotizing granulomatous inflammation, Necrosis	Altered Intercellular Communication	CD is characterized by a chronic granulomatous inflammation by necrotic scarring with aspects of full-thickness wall.	22309886
Inflammation, Malnutrition	Altered Intercellular Communication	The only significant determinants of SPhA were malnutrition (854%; P<00001) and inflammation (96 %; P<00001).	22309898
Inflammation, Malnutrition	Altered Intercellular Communication	In conclusion, next to the established predictors, malnutrition and inflammation have a strong impact on PhA in sick individuals, which partly explains its prognostic power.	22309898
Inflammation, Malnutrition	Altered Intercellular Communication	When investigating the SPhA, only malnutrition and inflammation were found to be significant predictors, as a result of which the SPhA is considered a more suitable indicator of nutritional and health status.	22309898
Myelolipoma, Hyperplasia, Adrenal Cortex Diseases	Altered Intercellular Communication	Patients with adrenal cortex disorders, such as hyperplasias and neoplasms, particularly when associated with hormonal imbalances, may have an increased risk of developing myelolipomas.	22309953
Inflammation, Non-ST Elevation Myocardial Infarction by ECG Finding	Altered Intercellular Communication	The results are in concordance with previous data on non-STEMI patients, implying that a HLA-DRB1*01--related haplotype increases the risk of CAD, possibly though increased inflammation.	22310063
Inflammation	Altered Intercellular Communication	The impact of insulin resistance and inflammation on the association between sarcopenic obesity and physical functioning.	22310233
Interstitial inflammation	Altered Intercellular Communication	Interstitial inflammation was present in 25 biopsy specimens.	22310621
Inflammation, Panuveitis	Altered Intercellular Communication	Medications such as corticosteroids and immunosuppressive agents are used to reduce inflammation in patients with posterior or panuveitis.	22310876
Inflammation	Altered Intercellular Communication	However, abnormal delayed enhancement MRI (consistent with inflammation) was present in both the thickened and the normal pericardial segments.	22311855
Inflammation	Altered Intercellular Communication	The corrected visual acuity OD dropped to 0.06 due to anterior chamber inflammation and the intraocular pressure increased to 26 mmHg.	22312815
Inflammatory Bowel Diseases, Colorectal Carcinoma	Altered Intercellular Communication	Associations are well established between intestinal infection/inflammation or inflammatory bowel diseases and colorectal cancer (CRC).	22314042
Pancreatitis, Acute, Inflammation	Altered Intercellular Communication	Systemic inflammation affects hemostasis during severe acute pancreatitis (SAP).	22314345
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	The main outcomes of the study were to assess whether IL28B rs12979860 and rs8099917 polymorphisms, together with PNPLA3 rs738409 C>G polymorphism, are associated with lobular inflammation and fibrosis, in NAFLD patients.	22314430
Inflammation, Fatty degeneration, Hyperuricemia	Altered Intercellular Communication	Multivariate logistic regression analysis showed that age (OR 1.043, 95% CI 1.012-1.075, p=0.007), triglycerides (OR 1.005, 95% CI 1.000-1.010, p=0.04), hyperuricemia (OR 5.027, 95% CI 1.839-13.742, p=0.002), IL28B rs12979860 TT/TC (OR 0.219, 95% CI 0.101-0.472, p<0.001), and steatosis grade (OR 1.704, 95% CI 1.048-2.773, p=0.03) were independently linked to moderate-severe lobular inflammation.	22314430
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Finally, IL28B rs12979860 CC was associated with severe fibrosis (F3-F4) on univariate analysis, even if only older age (OR 1.064, 95% CI 1.026-1.104, p=0.001), high HOMA (OR 1.213, 95% CI 1.068-1.377, p=0.003), and lobular inflammation (OR 3.181, 95% CI 1.438-7.036, p=0.004), remained associated in multivariate logistic regression analysis.	22314430
Inflammation, Overweight	Altered Intercellular Communication	In addition to adipose tissue, recent studies suggest that skeletal muscle may also be a source of low-grade inflammation, particularly in inactive and/or overweight individuals.	22314623
Parkinson Disease, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histological study confirmed the diagnosis of idiopathic Parkinson's disease, and there was striking, dense collagenous fibrosis at the distal end of the right DBS lead associated with focal hemosiderin deposition, chronic inflammation, and mild gliosis.	22314706
ACSM3 gene, Pituitary Hormones, Anterior	Altered Intercellular Communication	SAH is associated with anterior pituitary dysfunction and GH is the most frequently found deficient hormone in the patients.	22315089
Metabolic Syndrome X	Altered Intercellular Communication	Male sex hormones play an important role in ED and variety of TDS and may have influence on the development of metabolic syndrome.	22315154
Inflammation, diabetic	Altered Intercellular Communication	Enterovirus RNA was found in diabetic patients more frequently than in control subjects and was associated with a clear inflammation response in the gut mucosa.	22315304
Communicable Diseases, Inflammation, diabetic	Altered Intercellular Communication	The results suggest that a large proportion of type 1 diabetic patients have prolonged/persistent enterovirus infection associated with an inflammation process in gut mucosa.	22315304
IL13 gene	Altered Intercellular Communication	Allergic rhinitis is a common upper respiratory tract inflammation associated with a significant morbidity in all the age groups.	22315746
Inflammation, Meckel Diverticulum, Gangrene	Altered Intercellular Communication	Histopathological examination of these specimens confirmed 2 cases with inflammation, one with gangrene and one ulcerated gastric mucosa in the Meckel's diverticulum.	22315842
Delirium, Inflammation	Altered Intercellular Communication	The cholinergic system and inflammation: common pathways in delirium pathophysiology.	22316182
Communicable Diseases, Inflammation	Altered Intercellular Communication	Vaginal pH is related to genital tract inflammation and changes in the bacterial flora, both suggested cofactors for persistence of human papillomavirus (HPV) infection.	22316377
Inflammation, Hypercapnia, Carotid Intima-Media Thickness, Thrombophilia, Atherosclerosis, Hypoxia, Endothelial dysfunction, Hypertension, CTCAE, Hyperactive behavior	Altered Intercellular Communication	Its pathophysiological consequences (hypoxia, hypercapnia, micro-arousals, sympathetic hyperactivity, oxidative stress, systemic inflammation and hyper-coagulability) are implicated in the development of hypertension, endothelial dysfunction and higher intima-media thickness (IMT) values, all elements known to lead to atherosclerosis.	22317765
Inflammation, Inflammatory lung disease, Hemoptysis	Altered Intercellular Communication	Serum vascular endothelial growth factor and angiopoietin-2 are associated with the severity of systemic inflammation rather than the presence of hemoptysis in patients with inflammatory lung disease.	22318826
Inflammation, Hypoxia	Altered Intercellular Communication	Vascular endothelial growth factor (VEGF) and angiopoietin-2 (Ang-2) are major mediators of angiogenesis and are induced by tissue inflammation and hypoxia.	22318826
Inflammation, Inflammatory disorder, Hemoptysis	Altered Intercellular Communication	The purpose of this study was to investigate whether serum VEGF and Ang-2 are associated with the presence of hemoptysis and the extent of systemic inflammation in patients with inflammatory lung diseases.	22318826
Inflammation, Inflammatory disorder, Hemoptysis	Altered Intercellular Communication	Our study suggests that serum VEGF and Ang-2 levels are associated with PaO2 and the severity of inflammation rather than the presence of hemoptysis in patients with inflammatory lung diseases.	22318826
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Markers of inflammation and coagulation may be modulated by enteral feeding strategy.	22318965
Acute respiratory failure, Observation Method - Coagulation, Inflammation, Critical Illness	Altered Intercellular Communication	EN strategy in critically ill patients with acute respiratory failure does not significantly modify inflammation and coagulation by day 6, but trophic feeds may have some modest effects in attenuating inflammation and coagulation.	22318965
Inflammation	Altered Intercellular Communication	This gene dense region plays an important role in inflammation, immunity, and self-cell recognition.	22319020
Inflammation, Atherosclerosis	Altered Intercellular Communication	MHC genes regulate inflammation and T-cell responses that contribute importantly to the initiation and propagation of atherosclerosis.	22319020
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Recently, pentraxin-3 (PTX3) has been proposed to be a specific marker of vascular inflammation, yet its association with atherosclerosis is still unclear.	22319633
Inflammation, vascular inflammations	Altered Intercellular Communication	Unlike C-reactive protein, PTX3 is not a component of the classic acute phase response (systemic inflammation) but appears to be more specific for vascular inflammation.	22319633
Inflammation, Ulcer	Altered Intercellular Communication	The patient was in precarious hygienic condition, and was suffering from localized ulcerated foot ulcers with significant inflammation extending up to the knee.	22320020
Inflammation	Altered Intercellular Communication	In all these abnormalities, infection/inflammation has been implicated.	22321000
Rupture, Inflammation, Leucocytic infiltrate, Stenosis Morphology, Dental Plaque	Altered Intercellular Communication	The major morphological characteristics of vulnerable plaque are big lipid core, thin fibrous cap, inflammatory infiltration, neovascularization, severe stenosis, plaque rupture, and endothelial denudation suggesting inflammation performed an important role in the formation of vulnerable plaque.	22321226
Autoimmune Diseases, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	[Association between systemic inflammation and autoimmunity parameters and plasma lipid in patients with rheumatoid arthritis].	22321280
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The purpose of this study was to observe the association between inflammation status/autoimmune antibodies and plasma lipid in patients with rheumatoid arthritis (RA).	22321280
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	This study showed that rheumatoid arthritis is associated with an abnormal lipid profile, especially in patients with increased inflammation markers and autoimmune antibodies.	22321280
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	It is believed that the one cause of CVD is red blood cell extravasation and local iron overload that could generate free radicals and iron-dependent inflammation.	22321300
Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	[The clinical characteristics of intra-acinar pulmonary artery inflammation and its effect on clinical parameters in smokers with normal lung function and patients with chronic obstructive pulmonary disease].	22321324
ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	To study the pathological characteristics of intra-acinar pulmonary artery inflammation and its correlation with smoking index and disease progression in smokers with normal lung function and smokers with chronic obstructive pulmonary disease (COPD).	22321324
ARCN1 gene	Altered Intercellular Communication	(1) Pulmonary arterial inflammation appears in smokers with normal lung function and smokers with COPD patients.	22321324
Inflammation	Altered Intercellular Communication	The patients with greater SDIs had lower Z-scores, which suggests a direct association between chronic inflammation from disease and a reduced BMD.	22321657
Inflammation, Fibrosis Assessment, Compression, Distortion	Altered Intercellular Communication	We postulate that age-related CC may predispose to OD and stress-induced FRFx, and that inflammation, fibrosis, and anatomic distortion in the surrounding soft tissues may contribute to SCV compression.	22322117
Inflammation, Lupus Erythematosus, Systemic, Autoimmune Diseases, Tissue damage, Lupus Erythematosus	Altered Intercellular Communication	Systemic lupus erythematosus (SLE) is an autoimmune disease that results in inflammation and tissue damage.	22323338
Inflammation, Neoplasms	Altered Intercellular Communication	Pathologic analyses revealed that all of the resected or biopsied seminal vesicle tissues had chronic nonspecific inflammation in the seminal vesicle wall, and no tumors were identified.	22323622
Inflammation	Altered Intercellular Communication	A biopsy from the site revealed chronic caseating granulomatous inflammation, positive for BCG Tokyo-172 strain on the multiplex polymerase chain reaction.	22323874
Inflammatory abnormality of the eye, Papilledema	Altered Intercellular Communication	While the ocular inflammation responded to high doses of oral prednisolone, the disc edema showed little improvement.	22323889
Inflammatory abnormality of the eye, Papilledema	Altered Intercellular Communication	After oral administration of methotrexate, the disc edema and ocular inflammation were resolved, and the dose of oral corticosteroid could be reduced.	22323889
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Chronic inflammation in rheumatoid arthritis is associated with vascular endothelial dysfunction.	22324946
Refractory anemias, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	In RA, endothelial dysfunction is part of the disease process and is mediated by AGEs-induced inflammation.	22324946
Inflammation, Obesity	Altered Intercellular Communication	Epicardial fat, cardiac dimensions, and low-grade inflammation in young adult monozygotic twins discordant for obesity.	22325087
Inflammation, Obesity	Altered Intercellular Communication	We studied the relations among acquired obesity, low-grade inflammation, and genetic factors in the accumulation of epicardial fat.	22325087
Inflammation, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	The close relation between epicardial fat and low-grade inflammation is likely to contribute to the development of cardiovascular disease in obesity.	22325087
Gastrointestinal inflammation	Altered Intercellular Communication	The neutrophil protein calprotectin has been investigated as a surrogate marker for intestinal inflammation.	22325175
Refractory anemias, Inflammation, Atherosclerosis	Altered Intercellular Communication	Many studies have shown subclinical atherosclerosis in RA is associated with CV risk factors and inflammation.	22325679
Sleep Apnea, Obstructive, Erectile dysfunction	Altered Intercellular Communication	Literature review suggests that OSAS induces a spectrum of abnormalities in neural, hormonal and vascular regulation that contribute to the development of ED (erectile dysfunction).	22325836
Inflammation, Autistic Disorder, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	Oxidative stress, inflammation and mitochondrial dysfunction have all been suggested to play key roles in autism and may be linked via alterations in cellular redox homeostasis.	22325990
nervous system disorder, Inflammation, Complications of Diabetes Mellitus, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	Both MG and AGEs can induce oxidative stress, inflammation and mitochondrial dysfunction and are implicated in diabetic complications and multiple, age-related neurological diseases.	22325990
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The connection between cancer and inflammation is widely recognized, yet the underlying molecular mechanisms are poorly understood.	22326055
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	We report here that TIPE2 provides a molecular bridge from inflammation to cancer by targeting the Ras signaling pathway.	22326055
Inflammation, Primary malignant neoplasm, Inflammatory disorder	Altered Intercellular Communication	Thus, TIPE2 is an inhibitor of both inflammation and cancer, and a potential drug target for inflammatory and neoplastic diseases.	22326055
Inflammation, Endotoxemia, Metabolic Syndrome X	Altered Intercellular Communication	Endotoxemia, characterized by an excess of circulating bacterial wall lipopolysaccharide, is associated with systemic inflammation and the metabolic syndrome.	22326433
Inflammation, Endotoxemia, Gastrointestinal Diseases, Metabolic Syndrome X	Altered Intercellular Communication	Therapeutic reagents that reduce endotoxemia might reduce systemic inflammation in patients with gastrointestinal diseases or metabolic syndrome.	22326433
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Effusion status was determined by clinical examination, radiographs were scored for OA changes, and inflammation grading used haematoxylin and eosin stained sections of synovium.	22326896
Inflammation, Stomach Carcinoma, precancerous lesions	Altered Intercellular Communication	So, our results indicated that the IL-1RN*2 allele may increase the risk of gastric cancer and precancerous lesions in the Southeast Brazilian population, reinforcing the importance of host genetic factors in the susceptibility to gastric cancer and the participation of cytokines in both the inflammation and the carcinogenic process.	22327782
Necrotizing enterocolitis in fetus OR newborn, Inflammation, Necrosis	Altered Intercellular Communication	During NEC pathogenesis, bacteria are able to penetrate innate immune defenses and invade the intestinal epithelial layer, causing subsequent inflammation and tissue necrosis.	22328592
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Anti-apolipoprotein A-1 IgG in patients with myocardial infarction promotes inflammation through TLR2/CD14 complex.	22329401
vascular inflammations, Cardiovascular Diseases	Altered Intercellular Communication	Toll-like receptor (TLR)-mediated vascular inflammation, inducible by - amongst other factors - auto-antibodies, is increasingly recognized as a potential mediator of cardiovascular disease.	22329401
Inflammation	Altered Intercellular Communication	These auto-antibodies promote inflammation by stimulating the TLR2/CD14 receptor complex, probably because of molecular mimicry, which may contribute to atherosclerosis-related complications in patients.	22329401
Inflammation	Altered Intercellular Communication	In this respect, physical activity may promote neuronal resilience by reducing inflammation.	22329653
Familial spinal arachnoiditis, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Spinal arachnoiditis is a rare disease caused by fibrosis and adhesion of the arachnoid membrane due to chronic inflammation.	22330119
Gastroesophageal reflux disease	Altered Intercellular Communication	(3) Acid-related sensitization within the gastroesophageal reflux disease population is not dependant on mucosal inflammation.	22330131
Orbital Pseudotumor	Altered Intercellular Communication	To evaluate the outcomes of patients with idiopathic sclerosing orbital inflammation (ISOI) treated with radiotherapy with or without surgery.	22331004
Inflammation, Scleritis, Edema, Structure of lamina episcleralis, Rheumatoid Arthritis	Altered Intercellular Communication	Scleritis is a rare, progressive and serious disease, the signs of which are inflammation and edema of episcleral and scleral tissues and is greatly associated with systemic rheumatoid diseases.	22331111
Inflammation, Asthma, Wheezing	Altered Intercellular Communication	Nasal cell DNA methylation, inflammation, lung function and wheezing in children with asthma.	22332661
Glycation End Products, Advanced	Altered Intercellular Communication	S100A8/A9 complex is an inflammation-associated biomarker, which binds toll-like receptor 4 and was associated with the receptor for advanced glycation end-products.	22333479
ARCN1 gene, Inflammation, Pulmonary Hypertension, Tumor necrosis, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The levels of C-reactive protein (CRP), tumor necrosis factor (TNF)-a, brain natriuretic peptide (BNP) and endothelin-1 (ET-1) were investigated to analyze the systemic inflammation in chronic obstructive pulmonary disease (COPD) patients with and without pulmonary hypertension.	22333502
ARCN1 gene, Inflammation, Pulmonary Hypertension	Altered Intercellular Communication	The level of CRP, ET-1 and BNP were related to pulmonary hypertension in COPD patients, suggesting that systemic inflammation play a role in the pathogenesis of pulmonary hypertension in COPD.	22333502
Fibrosis, Liver, Portal inflammation, Hepatitis C	Altered Intercellular Communication	High prevalence of autoantibodies to C-reactive protein in patients with chronic hepatitis C infection: association with liver fibrosis and portal inflammation.	22333691
Inflammation, Fibrosis Assessment, Hepatitis C	Altered Intercellular Communication	We conclude that anti-CRP antibodies are frequently observed in chronic HCV infection and could be a useful marker of advanced fibrosis and portal inflammation.	22333691
Ulceration, CTCAE, Inflammatory abnormality of the eye	Altered Intercellular Communication	The patient subsequently reported a history of recurrent oral ulceration and intermittent occular inflammation.	22333754
Inflammation	Altered Intercellular Communication	They predominantly resulted from chronic inflammation of the middle ear.	22334160
Inflammation, Cerebral abscess	Altered Intercellular Communication	Cerebral abscesses remain one of the most severe complications related with inflammation of the middle ear.	22334160
Airway structure, Asthma	Altered Intercellular Communication	Chronic airway inflammation in asthmatic patients results in structural airway changes, including angiogenesis.	22336080
Inflammation, Tumor necrosis, Choline Dehydrogenase, Mitochondrial, Diabetes Mellitus	Altered Intercellular Communication	However, BC was positively associated with markers of inflammation in men with CHD (particularly vascular endothelial growth factor) and in men with diabetes (particularly interleukin-1b and tumor necrosis factor-a).	22336131
Inflammation, Choline Dehydrogenase, Mitochondrial, Diabetes Mellitus	Altered Intercellular Communication	In an elderly male population, estimated BC exposures were positively associated with markers of systemic inflammation but only in men with CHD or diabetes.	22336131
Crohn Disease, Inflammation	Altered Intercellular Communication	In Crohn's disease (CD), chronic gut inflammation leads to loss of mucosal barrier integrity.	22336288
Inflammation	Altered Intercellular Communication	Although previous studies have suggested that inflammation and lipid profile may be involved in those pathophysiological events, it remains controversial to date.	22336660
Inflammation, Nail Diseases	Altered Intercellular Communication	Our data suggest that DP inflammation is central in the development of psoriatic nail disease.	22337245
Inflammation, Injury of liver	Altered Intercellular Communication	Among HIV-infected individuals, independent of CD4, HIV-1 RNA, and age, hemoglobin and markers of liver and renal injury are associated with inflammation.	22337823
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	(2) Pathological inflammation and fibrosis Staging were no statistical difference between two groups patients.	22338213
Inflammation, Spondylitis	Altered Intercellular Communication	Investigation of two novel biochemical markers of inflammation, matrix metalloproteinase and cathepsin generated fragments of C-reactive protein, in patients with ankylosing spondylitis.	22339813
Inflammation, Sacroiliac joint structure, Spondylitis	Altered Intercellular Communication	Ankylosing spondylitis (AS) is a chronic inflammation of the spine and the sacroiliac joints.	22339813
Inflammation	Altered Intercellular Communication	These cleavage products may provide additional information on systemic inflammation as compared to that of full-length CRP.	22339813
Inflammation	Altered Intercellular Communication	These data suggest that different pools of CRP may provide insight into the inflammation processes in AS.	22339813
Inflammation	Altered Intercellular Communication	RATIONALE : Preclinical work demonstrates that the transcription factor peroxisome proliferator-activated receptor gamma plays an important role in augmenting phagocytosis while modulating oxidative stress and inflammation.	22340518
Coughing, Pain Distress Question, Inflammation, Bothered by Vomiting	Altered Intercellular Communication	Symptoms varied between the different anatomical systems, with cough as predominant when concerning aspiration, local pain or inflammation in inhalation and insertion, and vomiting in for the FBs ingestion cases.	22341887
Inflammation	Altered Intercellular Communication	Systemic inflammation has been considered as one of major pathophysiologic alterations in AECOPD.	22343073
Inflammation, Traumatic injury, Acute kidney injury	Altered Intercellular Communication	Kidneys with acute injury showed increased expression of 394 transcripts associated with the repair response to injury, including many epithelium-like injury molecules tissue, remodeling molecules, and inflammation molecules.	22343120
Inflammation	Altered Intercellular Communication	NF-kB is a family of transcription factors that play a central role in mediating cellular response to damage, stress, and inflammation.	22343279
Inflammation, diabetic	Altered Intercellular Communication	Plasma levels of soluble CD36, platelet activation, inflammation, and oxidative stress are increased in type 2 diabetic patients.	22343420
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation, oxidative stress, and platelet activation are involved in type 2 diabetes and its complications.	22343420
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	sCD36, platelet activation, inflammation, and oxidative stress are increased in type 2 diabetes.	22343420
Inflammation, Endothelial dysfunction, Stiff toe	Altered Intercellular Communication	Low-grade inflammation, but not endothelial dysfunction, is associated with greater carotid stiffness in the elderly: the Hoorn Study.	22343535
Inflammation, Endothelial dysfunction, Cardiovascular Diseases	Altered Intercellular Communication	Biomarkers of low-grade inflammation and endothelial dysfunction are associated with cardiovascular disease.	22343535
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Arterial stiffening may be a mechanism through which low-grade inflammation and (or) endothelial dysfunction lead to cardiovascular disease.	22343535
Inflammation, Endothelial dysfunction, Stiff toe	Altered Intercellular Communication	Therefore, we investigated whether low-grade inflammation and endothelial dysfunction were associated with greater carotid stiffness in a population-based cohort of elderly individuals.	22343535
Inflammation	Altered Intercellular Communication	These data suggest that low-grade inflammation, in the elderly, plays an important role in carotid artery remodelling and stiffening.	22343535
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Systemic inflammation and survival of patients with prostate cancer: evidence from the Glasgow Inflammation Outcome Study.	22343838
Inflammation, Prostate carcinoma	Altered Intercellular Communication	There is some evidence that systemic inflammation may be associated with survival in patients with prostate cancer; however, it is unclear whether this is independent of grade.	22343838
Prostate carcinoma	Altered Intercellular Communication	Inflammation-based prognostic scores predict outcome in patients with prostate cancer and should be added to their routine clinical assessment.	22343838
Malignant mesothelioma, Secondary malignant neoplasm of pleura, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	A definitive diagnosis was obtained in all cases: malignant mesothelioma in 13 cases, other malignancies (pleural metastases) in 8 cases and non-specific inflammation in 3 patients.	22345186
Inflammation, Asthma	Altered Intercellular Communication	The neutrophilic inflammatory phenotype is associated with systemic inflammation in asthma.	22345378
Inflammation, Asthma	Altered Intercellular Communication	The role of systemic inflammation in asthma is unclear.	22345378
Inflammatory, Inflammation, Asthma	Altered Intercellular Communication	The aim of this study was to compare systemic inflammation in subjects with stable asthma, categorized by airway inflammatory phenotype, with healthy control subjects.	22345378
neutrophilic, Asthma, Inflammation	Altered Intercellular Communication	The asthma (neutrophilic) group had increased systemic inflammation compared with the asthma (nonneutrophilic) and healthy control groups, with median (interquartile range) CRP levels of 5.0 (1.6-9.2), 1.8 (0.9-5.3), and 1.8 (0.8-4.1) mg/L (P = .011), respectively, and IL-6 levels of 2.1 (1.5-3.1), 1.4 (1.0-2.1), and 1.1 (0.8-1.5) pg/mL (P < .001), respectively.	22345378
Airway structure, Inflammation, Asthma	Altered Intercellular Communication	Systemic inflammation is increased in patients with asthma with neutrophilic airway inflammation and associated with worse clinical outcomes.	22345378
Inflammation	Altered Intercellular Communication	Systemic inflammation may contribute to the pathophysiology of neutrophilic asthma.	22345378
Inflammation, HIV-1 Infection Pathway, Pneumonia, Interstitial, Cessation of life, Respiratory Failure	Altered Intercellular Communication	Protective role of peroxisome proliferator-activated receptor-g. HIV-1-induced interstitial pneumonitis (IP) is a serious complication of HIV-1 infection, characterized by inflammation and cellular infiltration in lungs, often leading to respiratory failure and death.	22345580
Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Ongoing inflammation including activation of the complement system is a hallmark of systemic lupus erythematosus (SLE).	22345666
Chronic kidney disease stage 5, Kidney Failure, Chronic	Altered Intercellular Communication	In patients with end stage renal disease (ESRD) we observed protection from inflammation-associated mortality in CCR5D32 carriers, leading to CCR5 deficiency, suggesting impact of CCR5D32 on inflammatory processes.	22348061
Kidney Failure, Chronic	Altered Intercellular Communication	These differences may be involved in the previously observed protection from inflammation-associated mortality in ESRD patients carrying CCR5D32.	22348061
ARCN1 gene, Lung Diseases, Obstructive, Airway structure	Altered Intercellular Communication	Asthma and COPD are obstructive airway diseases related to chronic airway inflammation.	22348544
Inflammation	Altered Intercellular Communication	Potential antigens inducing sarcoid inflammation include mycobacterial and auto-antigens.	22349068
Gingivitis, Periodontal Diseases	Altered Intercellular Communication	Adjunctive use of slow-released chlorhexidine might be considered in the management of periodontal disease and gingival inflammation to reduce the need for periodontal surgery.	22350036
Inflammation, hepcidin	Altered Intercellular Communication	Surgical inflammation induces hepcidin production after abdominal surgery.	22350482
Inflammation, hepcidin	Altered Intercellular Communication	Hepcidin, a key regulator of iron homeostasis, is also a marker of acute inflammation.	22350482
Airway structure, ARCN1 gene	Altered Intercellular Communication	Alveolar nitric oxide (CA(NO)) has been suggested as a surrogate marker of distal airway inflammation in COPD.	22350679
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	The cytology patterns observed included granulomatous inflammation and necrosis with or without acid fast bacilli.	22351190
Inflammation, Nutritional anemia, Anemia, Cessation of life, Chronic Kidney Diseases	Altered Intercellular Communication	Of those with anemia (n = 862, deaths = 491), 24% had nutritional anemia, 11% had anemia of chronic renal disease, 26% had anemia of chronic inflammation, and 39% had unexplained anemia.	22351246
Inflammation, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	Compared to persons without anemia, we found the following RRs for the type of anemia: nutritional (2.34, p < 0.0001), chronic renal disease (1.70, p < 0.0001), chronic inflammation (1.48, p < 0.0001), and unexplained (1.26, p < 0.01).	22351246
Systemic disease	Altered Intercellular Communication	There have been many causes identified ranging from chronic aging joint changes to inflammatory conditions or systemic disorders.	22351538
Inflammatory abnormality of the eye, Candidiasis, Chronic Mucocutaneous, Stenosis of nasolacrimal duct	Altered Intercellular Communication	Given the strong association between erosive mucocutaneous LP and multisite scarring sequelae, it is not unexpected that ocular inflammation may lead to lacrimal duct stenosis.	22351823
Inflammation	Altered Intercellular Communication	The histological findings revealed chronic inflammation of the pleura on a hematoxylin-eosin (HE) stain, but treatment with an increased dose of corticosteroid did not improve his effusion.	22352049
Metabolic Diseases, Amenorrhea, Chromosome Aberrations, Hormone abnormality, teratologic, Gonadal Dysgenesis, Vulva	Altered Intercellular Communication	In general, primary amenorrhea is caused by gonadal dysgenesis, anomalies of internal or external genitalia with or without chromosomal anomalies, and sometimes by hormonal abnormalities that affect the hypothalamus, pituitary, ovaries, adrenals or thyroid, or by chronic or metabolic diseases.	22353374
Inflammation	Altered Intercellular Communication	Systemic inflammation is associated with vessel wall damage, upregulation of procoagulants, downregulation of anticoagulants, and suppression of fibrinolysis.	22353382
Inflammation	Altered Intercellular Communication	The activity and chronic inflammation scores were significantly decreased in regression group.	22353533
Inflammation	Altered Intercellular Communication	In non-regression group, there was no significant difference in activity scores, but the chronic inflammation score was significantly increased.	22353533
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	A 59-year-old man with a long history of under-treated diabetes mellitus presented with severe inflammation that had spread from the sinus to the left orbital cavity.	22354231
Sinusitis, Communicable Diseases, Inflammation	Altered Intercellular Communication	Based on the presence of central nervous system (CNS) inflammation and vascular involvements that spread from the sinusitis, we tentatively diagnosed this patient as having invasive fungal CNS infection, i.e.	22354231
Necrotizing granulomatous inflammation, Coagulative necrosis	Altered Intercellular Communication	Microscopically, the mass was composed of chronic granulomatous inflammation with extensive coagulation necrosis and parasite-like structure, which was revealed as parasitic vesicles and laminated layer delineated by periodic acid-Schiff (PAS) stain.	22355210
Catatonia, Familial episodic pain syndrome	Altered Intercellular Communication	Catatonia is an episodic syndrome characterized by specific affective, behavioral, and motor symptoms and thought to result from regional abnormalities in neurotransmitter function.	22356926
Arterial Stiffness, Diabetes Mellitus, Insulin-Dependent, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Arterial stiffness is increased in patients with type 1 diabetes without cardiovascular disease: a potential role of low-grade inflammation.	22357186
Arterial Stiffness, Inflammation, Diabetes Mellitus, Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	To investigate the relationship between arterial stiffness and low-grade inflammation in subjects with type 1 diabetes without clinical cardiovascular disease.	22357186
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	In men, multiple linear regression analysis showed that the following variables were associated independently with aPWV: age, BMI, type 1 diabetes, and low-grade inflammation (R(2) = 0.543).	22357186
Arterial Stiffness, Diabetes Mellitus, Insulin-Dependent, Inflammation	Altered Intercellular Communication	In men with type 1 diabetes, low-grade inflammation is independently associated with arterial stiffness.	22357186
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	While MetS is a proinflammatory state, there is a paucity of data on cellular inflammation in MetS.	22357188
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Low-grade inflammation seems to play a crucial role in development and progression of chronic heart failure (CHF).	22357441
methyldopa, Inflammation	Altered Intercellular Communication	Although pathogenic factors, such as oxidative stress, inflammation and genetics are thought to contribute to the development of AMD, little is known about the relationships and priorities between these factors.	22357958
Inflammation	Altered Intercellular Communication	Therefore, we propose a consecutive pathogenic pathway involving photic stress, oxidation of phospholipids and chronic inflammation, leading to angiogenesis.	22357958
methyldopa, Inflammation	Altered Intercellular Communication	These findings add to the current understanding of AMD pathology and suggest protection from oxidative stress or suppression of the subsequent inflammation as new potential therapeutic targets for AMD.	22357958
palladium, Inflammation, Anemia	Altered Intercellular Communication	Lower HMA level, which might be caused by chronic inflammation, anemia and accumulation of dialyzable uremic toxin(s), is closely related to serious CVD incidence among PD patients.	22358613
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	In addition, patients with NAFLD had significantly decreased circulating EPC levels (all P<0.05), attenuated EPC functions, and enhanced systemic inflammation compared to controls.	22359630
Inflammatory Bowel Diseases, Inflammation, Primary malignant neoplasm, Communicable Diseases, Crohn Disease, Reactive systemic amyloidosis	Altered Intercellular Communication	Secondary amyloidosis (AA) is a rare but serious complication that occurs in the context of cancer, chronic inflammation and chronic infectious diseases, including inflammatory bowel disease, mainly long-standing Crohn's disease.	22359896
ARCN1 gene, Inflammation, Osteoporosis	Altered Intercellular Communication	COPD patients have many risk factors for osteoporosis, such as low BMI, decreased activity, systemic inflammation, and use of corticosteroids.	22360380
Seizures, Cessation of life, Synaptic cleft, Respiratory arrest	Altered Intercellular Communication	The irreversible inhibition of AChE causes the neurotransmitter to accumulate in the synaptic cleft, leading to overstimulation of cholinergic receptors, seizures, respiratory arrest, and death.	22360473
Inflammation, Calcinosis	Altered Intercellular Communication	Reoperation is associated with increased morbidity and is not always successful because of underlying tissue friability, inflammation, or calcification.	22361595
Pleural Effusion, CTCAE, Inflammation, Fever, CTCAE	Altered Intercellular Communication	Thus, in patients with prolonged fever and systemic symptoms, a 'bland' left-sided pleural effusion may be a diagnostic clue to underlying inflammation of large thoracic arteries.	22362125
ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by the abnormal and chronic lung inflammation.	22363103
ARCN1 gene, Inflammation	Altered Intercellular Communication	Our data suggest that lung fibroblasts participate in the chronic inflammation in COPD by releasing IL-6 and IL-8, and low dose theophylline can alleviate the proinflammatory mediators' production by fibroblasts.	22363103
Inflammation, Stiff toe, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Pedometer-determined physical activity is linked to low systemic inflammation and low arterial stiffness in Type 2 diabetes.	22364114
Inflammation, Stiff toe, Obesity, Abdominal, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	We conclude that physical activity measured with pedometer was associated not only with less abdominal obesity, but also with decreased systemic low-grade inflammation as well as with low arterial stiffness, in people with Type 2 diabetes.	22364114
Inflammation, Renal calcium wasting, Zinc deficiency	Altered Intercellular Communication	Further studies should clarify whether inflammation related processes such as renal wasting contribute to zinc deficiency and underlie the adverse health consequences of low serum zinc levels.	22365070
Coinfection, Inflammation, Lyme Disease, Hepatitis	Altered Intercellular Communication	Although hepatitis complicating the course of Lyme disease has been described in literature, the marked inflammation in our patient led us to investigate the possibility of a co-infection.	22365471
Headache	Altered Intercellular Communication	The significant decrease in headache prevalence observed during pregnancy may be the result of a pregnancy-specific hormonal status.	22365591
Inflammation, Fracture	Altered Intercellular Communication	Chronic inflammation impairs recovery among the 1.6 million people who suffer from hip fracture annually.	22365613
Inflammation	Altered Intercellular Communication	The association weakened but remained statistically significant after additional adjustment for systemic markers of inflammation.	22366234
Hashimoto Disease, Chronic inflammation, Endothelial dysfunction, Haiti	Altered Intercellular Communication	The etiopathogenesis of Hashimoto's thyroiditis (HT) has not been clearly elucidated although the role of chronical inflammation and endothelial dysfunction has been established.	22366404
Inflammation, Traumatic	Altered Intercellular Communication	Lifetime exposure to traumatic psychological stress is associated with elevated inflammation in the Heart and Soul Study.	22366689
Inflammation	Altered Intercellular Communication	While the biological mechanisms of these effects are not known, inflammation may play a key role as it is both elevated by psychological stress and involved in the development and progression of CVD.	22366689
Inflammation, Traumatic injury	Altered Intercellular Communication	In a prospective study of patients with stable CVD (n=979), we examined if higher lifetime trauma exposure was associated with elevated levels of inflammation at baseline and at five-year follow-up, and with greater increases in inflammation over time.	22366689
Inflammation, Tumor necrosis	Altered Intercellular Communication	Inflammation was indexed by a composite score incorporating the inflammatory markers interleukin-6 (IL-6), tumor necrosis factor-a (TNF-a), C-reactive protein (CRP) and resistin.	22366689
Inflammation, Traumatic injury	Altered Intercellular Communication	Higher trauma exposure was associated with elevated inflammation at baseline (b=.09, p=.01) and at five-year follow-up (b=.09, p=.03).	22366689
Inflammation, Traumatic injury	Altered Intercellular Communication	While levels of inflammation increased from baseline to follow-up in the sample, there was no significant association between trauma exposure and rate of change in inflammation.	22366689
Inflammation, Mental disorders, Traumatic injury	Altered Intercellular Communication	Findings were robust to adjustments for sociodemographic factors and psychiatric disorders, but health behaviors appeared to contribute to the association between trauma and inflammation at follow-up.	22366689
Inflammation, Traumatic injury	Altered Intercellular Communication	This is the first large-scale demonstration of an association between lifetime trauma exposure and inflammation.	22366689
Inflammation, Traumatic	Altered Intercellular Communication	High lifetime exposure to traumatic stress may contribute to an accelerated rate of CVD progression through elevated inflammation.	22366689
Tissue injury, MS gene	Altered Intercellular Communication	Our data suggest that the inflammation-associated oxidative burst in activated microglia and macrophages plays an important role in demyelination and free radical-mediated tissue injury in the pathogenesis of multiple sclerosis.	22366799
Inflammation, Abnormal degeneration, Elastosis perforans serpiginosa	Altered Intercellular Communication	Processes associated with tissue degeneration but not with inflammation are highly prevalent among subjects with EPS.	22367046
Carcinogenic Chlorinated Hydrocarbon, Inflammation	Altered Intercellular Communication	CHC patients, irrespective of liver function, had higher frequencies of Tregs than healthy subjects; however, only CHC patients with inflammation showed enhanced immunosuppressive function of Tregs.	22367277
Inflammation	Altered Intercellular Communication	Associations of inflammation with age-related pathologies are documented; however, it is not understood how changes in inflammation over time impact healthy aging.	22367431
Inflammation, BDI - Functional Impairment	Altered Intercellular Communication	Although increases in inflammation markers over 9 years were associated with higher concurrent risk of functional impairment and subsequent CVD events and mortality, final levels of each biomarker appeared to be more important in determining risk of subsequent events than change over time.	22367431
Inflammation	Altered Intercellular Communication	We previously demonstrated that NF-kB, a transcription factor traditionally associated with inflammation, plays a unique protective role in the neonatal lung.	22367785
Psychotic Disorders, Impaired cognition, Inflammation, Schizophrenia	Altered Intercellular Communication	Severe psychosis and mild cognitive decline without other neurological features, meeting the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, text revision diagnostic criteria for schizophrenia, can result from brain inflammation associated with elevated serum anti-GADAbs.	22367838
Airway structure	Altered Intercellular Communication	Polymorphisms in nitric oxide synthase genes (NOS1, NOS2, and NOS3) have been suggested to have a major impact on fraction of exhaled nitric oxide (FENO), a biomarker of airway inflammation.	22368302
Familial spinal arachnoiditis, Inflammation	Altered Intercellular Communication	Spinal arachnoiditis describes inflammation of the meninges, subarachnoid space and, in most cases, also involve the pial layer.	22369357
Pregnancy loss, Amenorrhea	Altered Intercellular Communication	A novel luteinizing hormone/chorionic gonadotropin receptor mutation associated with amenorrhea, low oocyte yield, and recurrent pregnancy loss.	22369774
Communicable Diseases, Primary malignant neoplasm, Fever of Unknown Origin, Vasculitis, CTCAE	Altered Intercellular Communication	The causes of FUO in the other PET positive patients were: infection (n = 3), vasculitis (n = 3), non-infectious inflammatory conditions (n = 2) and cancer (n = 1).	22369860
Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Exanthema	Altered Intercellular Communication	Histological examination showed dermal-ipodermal inflammation with evidence of leukocytoclastic vasculitis principally interesting the small venules The cutaneous rash resolved after 2 weeks.	22370576
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	All IBD and non-IBD patients who had a FC measurement available before full endoscopic evaluation for suspected bowel inflammation were examined.	22370604
ACSM3 gene, Inflammation, Subarachnoid Hemorrhage, Aneurysmal, Vasospasm	Altered Intercellular Communication	Vasospasm is a major contributor to morbidity and mortality in aneurysmal subarachnoid hemorrhage (SAH), with inflammation playing a key role in its pathophysiology.	22370810
Inflammation, Gallbladder Biliary Intraepithelial Neoplasia, Fibrosis Assessment	Altered Intercellular Communication	Inflammation and fibrosis of the gallbladder wall were more common in tissue with gallbladder dysplasia/carcinoma than in benign tissue 12/25 (48%) versus 4/28 (12%) (p < 0.01) and in 13/21 (62%) versus 3/32 (9%) (p < 0.0001), respectively.	22370917
Lesion, Inflammation	Altered Intercellular Communication	Caries lesions on abutment teeth were seen in 31.6% of patients, and 35.6% showed inflammation of the periodontal tissue surrounding the abutment teeth.	22371834
Rheumatoid Arthritis, BDI - Functional Impairment, Swelling, Inflammatory disorder, Arthritis	Altered Intercellular Communication	Rheumatoid Arthritis is a chronic inflammatory disease resulting in joint inflammation (particularly joints of hands, wrists, feet, knees, ankles, and shoulder) that is manifested by swelling and functional impairment.	22372341
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	There was no clear-cut correlation between the pattern of alanine aminotransferase levels and changes in steatosis, inflammation, hepatocyte ballooning, or fibrosis stage over time.	22373863
Inflammation, Vascular Diseases	Altered Intercellular Communication	Blood vessels and soft tissues are injured by inflammation as the primary target of collagen vascular diseases.	22373989
Autoimmune Diseases, Inflammation, mitomycin	Altered Intercellular Communication	Inflammation due to autoimmune disease is believed to play an important role in the formation of MTC.	22374595
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	One of the mechanisms proposed by which H. pylori causes gastric cancer (GC) is through DNA damage due to chronic inflammation.	22374853
Inflammation, Pain, Postoperative	Altered Intercellular Communication	HA-CMC can decrease immediate postoperative pain arising from tissue adhesion and inflammation, thus reducing postoperative mastication pain.	22377324
Inflammation, Renal carcinoma	Altered Intercellular Communication	Prospective study of the role of inflammation in renal cancer.	22377628
Airway structure	Altered Intercellular Communication	Subclinical changes in airway inflammation can be measured by fractional exhaled nitric oxide (FeNO).	22377682
Inflammation, Obesity	Altered Intercellular Communication	Adiposity, traditional food intake, long-chain RBC PUFA status, and inflammation were positively associated with SF and food insecurity, smoking, and H. pylori seropositivity were negatively associated with SF.	22378332
Inflammation, Heart failure	Altered Intercellular Communication	Adipose tissue inflammation and adiponectin resistance in patients with advanced heart failure: correction after ventricular assist device implantation.	22379072
Inflammation, Heart failure	Altered Intercellular Communication	Heart failure (HF) is characterized by inflammation, insulin resistance, and progressive catabolism.	22379072
Degenerative polyarthritis, Inflammation, Osteoporosis	Altered Intercellular Communication	Recent evidence suggests that inflammation may play a role in osteoporosis (OP) and osteoarthritis (OA).	22380539
Nightmares, Migraine Disorders, Hay fever, Motion Sickness, Asthma, Epilepsy	Altered Intercellular Communication	Adolescent migraine is associated with inflammatory conditions such as asthma and seasonal allergies, as well as with epilepsy, persistent nightmares, and motion sickness.	22381023
Pneumonitis	Altered Intercellular Communication	Pulmonary inflammation is a substantive prognostic factor for Ivor Lewis operations.	22381051
Rheumatoid Arthritis, Temporomandibular Joint	Altered Intercellular Communication	Rheumatoid arthritis is a chronic inflammatory condition that can result in progressive destruction of the articular surfaces of the joints, including the temporomandibular joint.	22381496
Inflammation, Chronic disease, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is a progressive chronic disease, in which inflammation plays a key role.	22382154
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	The positive associations between D-dimer and vWF and incident stroke remained after additional adjustment for markers of inflammation (C-reactive protein, IL-6).	22382157
Orbital Pseudotumor	Altered Intercellular Communication	There are very few reports of WG with orbital inflammation and exorbitism.	22382229
Orbital Pseudotumor	Altered Intercellular Communication	We report a case of a female patient who presented with exorbitism related to orbital inflammation secondary to WG, with renal involvement.	22382229
Communicable Diseases, Inflammation	Altered Intercellular Communication	Chronic inflammation is correlated with percentage of body fat independent of the burden of infection.	22382515
Inflammation, Ruptured simple cyst	Altered Intercellular Communication	Histopathologic findings of the excised mass were consistent with an epidermal inclusion cyst with surrounding moderate chronic inflammation and cyst rupture.	22382849
Inflammation, Stomach Carcinoma, Hyperplasia	Altered Intercellular Communication	Development of gastric cancer in nonatrophic stomach with highly active inflammation identified by serum levels of pepsinogen and Helicobacter pylori antibody together with endoscopic rugal hyperplastic gastritis.	22383377
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Meanwhile, endoscopic findings revealed that 11.7% of subjects showed RHG reflecting localized highly active inflammation, and cancer risk was significantly higher in patients with RHG than in patients without.	22383377
Chronic Kidney Diseases	Altered Intercellular Communication	At baseline, compared with controls, fasting CKD subjects had higher parathyroid hormone and fibroblast growth factor 23 levels and greater fractional excretion of phosphate.	22383746
Inflammation, Malignant Female Reproductive System Neoplasm	Altered Intercellular Communication	[Changes in calprotectin concentration--inflammation marker in serum of women with gynecological cancer].	22384614
Inflammation, Neoplasms	Altered Intercellular Communication	There is a relation between an impaired immune system, especially the process of inflammation and the pathogenesis of these tumors.	22384614
Inflammation, Peripheral Nervous System	Altered Intercellular Communication	Although MS is mostly a multifocal chronic inflammation of the central nervous system, peripheral nervous system can also be involved.	22384779
Inflammation, Sensorineural Hearing Loss (disorder)	Altered Intercellular Communication	Although the etiology of idiopathic sudden sensorineural hearing loss (SSNHL) remains unclear, the pathologically increased permeability of blood vessels, elucidated by gadolinium-enhanced magnetic resonance imaging (MRI), suggests the involvement of inflammation.	22385075
Inflammation, Sensorineural Hearing Loss (disorder)	Altered Intercellular Communication	Because permeability of blood vessels in the inner ear is frequently increased in patients with SSNHL, inflammation of the inner ear might be involved.	22385075
fluorouracil/mitomycin/streptozocin, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Oral submucous fibrosis (OSMF) is associated with paan chewing, altered collagen metabolism, inflammation and the upregulation of numerous cytokines.	22385081
vascular inflammations, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Oxidative stress results from an imbalance of prooxidants and antioxidants and leads to endothelial dysfunction that promotes vascular inflammation and atherosclerosis.	22385338
Inflammation, Fatty degeneration, Hepatitis C	Altered Intercellular Communication	HCV infection is a risk factor for earlier and facilitated occurrence of CA via viral load and steatosis which modulate atherogenic factors such as inflammation and dysmetabolic milieu.	22385985
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Postoperative inflammation (48% vs 16%) and glaucoma (40% vs 16%) were seen more frequently in eyes with sutures as compared to eyes with glue.	22386370
Malignant neoplasm of urinary bladder, Inflammation	Altered Intercellular Communication	Influence of urinary tract instrumentation and inflammation on the performance of urine markers for the detection of bladder cancer.	22386412
Inflammation, Hematuria, CTCAE	Altered Intercellular Communication	To evaluate the impact of inflammation and sampling on cytology, immunocytology, and fluorescence in situ hybridization (FISH) in comparison with NMP22 in hematuria patients.	22386412
Inflammation	Altered Intercellular Communication	False-positive results were compared with regard to the presence or absence of inflammation and mechanical manipulation.	22386412
Inflammation	Altered Intercellular Communication	Inflammation led to a rise in false-positive NMP22 test results (85.3% vs 61.4%, P < .0001).	22386412
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Importantly, we showed that this association was independent of potential confounders, especially all of the MetS components and inflammation.	22386703
Primary malignant neoplasm	Altered Intercellular Communication	Therefore, this observation suggests that genetic variation in inflammation-related genes could be an important mediator of the complex interplay between ageing and cancer.	22387051
Inflammation, Autoimmune Atrophic Chronic Gastritis, Achlorhydria, Immune-mediated	Altered Intercellular Communication	Autoimmune atrophic gastritis (AIG) is characterized by immune-mediated chronic inflammation of the gastric body and fundus, leading to hypo-achlorhydria and vitamin B12 deficiency.	22387252
Peritonitis	Altered Intercellular Communication	Neutrophilic inflammation in experimental peritonitis in mice decreased iNKT cell T-box transcription factor 21 and GATA3 expression and a-galactosyl ceramide-induced cytokine production in vivo.	22387552
Inflammation	Altered Intercellular Communication	Our data reveal a novel regulatory axis whereby neutrophils reduce iNKT cell responses, which may be important in shaping the extent of inflammation.	22387552
Inflammation, exacerbation acute	Altered Intercellular Communication	One factor implicated in this process is systemic inflammation, an accompaniment of acute exacerbations.	22388793
Arthritis	Altered Intercellular Communication	Inflammation assessment in patients with arthritis using a novel in vivo fluorescence optical imaging technology.	22388997
Inflammation	Altered Intercellular Communication	Indocyanine green (ICG)-enhanced fluorescence optical imaging (FOI) is an established technology for imaging of inflammation in animal models.	22388997
Refractory anemias, Rheumatoid Arthritis, Inflammation, Cardiovascular morbidity	Altered Intercellular Communication	Rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity and mortality attributed to both classical risk factors and chronic inflammation.	22390577
Vasculitis	Altered Intercellular Communication	In late biopsies, high NK-cell transcript expression was associated with antibody-mediated rejection, correlating with microvascular inflammation and donor specific HLA antibody.	22390872
Tubulitis Assessment, Interstitial inflammation	Altered Intercellular Communication	However, some early biopsies with T cell-mediated rejection had high NK-cell transcript expression, as well as T cell transcripts, without evidence of antibody-mediated rejection or DSA, correlating with interstitial inflammation and tubulitis.	22390872
Inflammation, Atrophic, Natural Killer Cells	Altered Intercellular Communication	Both NK-cell and T cell transcripts were moderately increased in many kidneys with inflammation secondary to injury or atrophy scarring.	22390872
Inflammation, Atrophic	Altered Intercellular Communication	These results support the distinct role of NK cells in late antibody-mediated rejection, but indicate a role for NK-transcript expressing cells (NK cells or T cells with NK features) both in T cell-mediated rejection and in inflammation associated with injury and atrophy scarring.	22390872
Inflammation, Obesity, Abdominal	Altered Intercellular Communication	Overexpression of S100A8 and S100A9 in obese adipose tissue may be involved, at least partly, in not only high circulating levels of S100A8/A9 complex in abdominal obesity but also adipose and systemic tissue inflammation.	22390934
Inflammation, Necrosis	Altered Intercellular Communication	Muscle biopsy showed necrosis, inflammation, and positive HLA class I immunostaining.	22391471
Inflammation, Depression, CTCAE, Metabolic Syndrome X	Altered Intercellular Communication	Increased inflammation and lower platelet 5-HT in depression with metabolic syndrome.	22391518
Disease	Altered Intercellular Communication	For both disorders, impaired serotoninergic neurotransmission and inflammatory factors have been suggested.	22391518
Acute inflammation of orbit	Altered Intercellular Communication	This study reports 3 cases of acute orbital inflammation that occurred within 3 weeks of various dental procedures and offers a possible mechanism as to their cause.	22391741
Inflammation	Altered Intercellular Communication	The last individual had recurrent symptoms prompting lacrimal gland biopsy that demonstrated chronic, nongranulomatous inflammation without monoclonality.	22391741
Acute inflammation of orbit	Altered Intercellular Communication	The authors propose that a subset of acute orbital inflammation may represent an autoimmune response triggered by dental manipulation.	22391741
Communicable Diseases, Inflammation	Altered Intercellular Communication	These cases are suggestive of an atypical variant of noninfectious, microbe-induced inflammation.	22391741
Refractory anemias, Inflammation, Rheumatoid Arthritis, Peripheral	Altered Intercellular Communication	Chronic inflammation of the peripheral joints is a hallmark of rheumatoid arthritis (RA).	22391806
Inflammation, Microvascular Angina, Obesity	Altered Intercellular Communication	Obesity, inflammation and brachial artery flow-mediated dilatation: therapeutic targets in patients with microvascular angina (cardiac syndrome X).	22392186
Inflammation, physiopathological, Obesity	Altered Intercellular Communication	The results support the concept that low-grade inflammation and obesity may promote vascular dysfunction in these patients representing therapeutic targets for future research investigations.	22392186
Inflammation, Lupus Erythematosus, Systemic, Autoimmune Diseases, Acute and chronic inflammation, Lupus Erythematosus	Altered Intercellular Communication	Systemic lupus erythematosus (SLE) is an autoimmune disease with chronic or episodic inflammation in several organ systems, related to the presence of circulating and tissue-deposited immune complexes (ICs) that stimulate leukocytes through Fcg receptors (FcgR) with subsequent inflammation.	22392566
Inflammation, Retinitis Pigmentosa, polychondritis, Autoimmune Disorder, CTCAE	Altered Intercellular Communication	Relapsing polychondritis (RP) is a rare, generalized autoimmune disorder that is characterized by recurrent inflammation of various cartilaginous structures.	22392754
Inflammation	Altered Intercellular Communication	Pathological findings revealed chronic inflammation of the meninges, so prednisone was administered.	22392754
Inflammation, Neoplasms	Altered Intercellular Communication	In contrast to intestinal IFP, gastric tumours occur at higher age, show heavy inflammation and tend to be smaller.	22394371
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Biopsies showed denuded urothelium and inflammation of the submucosa without malignancy.	22394445
glycation, Inflammation	Altered Intercellular Communication	EN-RAGE is extracellular newly identified receptor for advanced glycation end-products binding protein playing a role in inflammation.	22394461
Atherosclerosis	Altered Intercellular Communication	Inflammation of the vascular wall is an essential event in the development of atherosclerosis, the main leukocytes of the inflammatory infiltrate being the monocyte/macrophages.	22395501
Inflammation	Altered Intercellular Communication	Therefore, it is particularly important to investigate the molecules involved in cardiac inflammation.	22395526
Rosacea	Altered Intercellular Communication	Papulopustular acne rosacea is a chronic inflammatory condition which can be difficult to treat.	22395584
Inflammation, Behcet Syndrome, irSD (Immune-Related Response Criteria)	Altered Intercellular Communication	Behcet's disease is known as a recurrent, multisystem inflammation and immune-related disease.	22396730
Inflammatory Bowel Diseases, Inflammation, Fracture, Ileum Perforation, CTCAE_3	Altered Intercellular Communication	He underwent abdominal CT, which revealed pelvis fractures, abnormal bowel wall of the terminal ileum (wall thickening and mucosal enhancement), peritoneal effusion within the pelvis, mesenteric nodes and extra-luminal gas within an area of mesenteric inflammation: these features were suggestive of ileum perforation associated with inflammatory bowel disease, most likely CD.	22398044
Granuloma, Inflammation, Specimen Type - Fistula, Fibrosis Assessment, Ileitis, Ulcer	Altered Intercellular Communication	Histological analysis revealed terminal ileitis with ulcers, non caseating granulomas and submucosal fibrosis, a transparietal fistula and a caecoappendicular inflammation, confirming CD.	22398044
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	This study suggests a potential role for Substance P serum levels in monitoring intestinal inflammation in patients with inflammatory bowel disease.	22398048
Inflammation	Altered Intercellular Communication	Inflammation was graded by endoscopic, clinical, histological and biochemical scoring.	22398079
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	However, our results demonstrate a significant association between TNF-a and renal function, suggesting a potential link between inflammation and the development of CKD.	22398717
Inflammation	Altered Intercellular Communication	These data also confirm the association between MAU and inflammation.	22398717
Inflammation, Neoplasms, Primary central nervous system lymphoma, Glioblastoma Multiforme Pathway, Cerebrovascular Disorders	Altered Intercellular Communication	There were 13 patients with PCNSL and 24 patients with other diseases such as glioma, metastatic tumor, inflammation, or cerebrovascular disease.	22399193
vascular inflammations, diabetic	Altered Intercellular Communication	Genistein prevents hyperglycemia-induced monocyte adhesion to human aortic endothelial cells through preservation of the cAMP signaling pathway and ameliorates vascular inflammation in obese diabetic mice.	22399524
vascular inflammations, Atherosclerosis, Diabetes Mellitus	Altered Intercellular Communication	Hyperglycemia-induced vascular inflammation resulting in the enhanced monocyte-endothelial cell (EC) interaction is the key event in the pathogenesis of atherosclerosis in diabetes.	22399524
vascular inflammations	Altered Intercellular Communication	We conclude that genistein improves diabetes-caused vascular inflammation, which may be mediated through promoting the cAMP/PKA pathway.	22399524
Rheumatoid Arthritis	Altered Intercellular Communication	Gene expression analysis of rheumatoid arthritis synovial lining regions by cDNA microarray combined with laser microdissection: up-regulation of inflammation-associated STAT1, IRF1, CXCL9, CXCL10, and CCL5.	22401175
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	The main histological change in rheumatoid arthritis (RA) is the villous proliferation of synovial lining cells, an important source of cytokines and chemokines, which are associated with inflammation.	22401175
Kidney Failure, Chronic, Periodontitis	Altered Intercellular Communication	Chronic periodontitis (CP) and end-stage renal disease (ESRD) are complex inflammatory conditions.	22401717
Tumor necrosis, Inflammation	Altered Intercellular Communication	[Tumor necrosis factor as an early marker of inflammation in healthy smokers].	22401725
Degenerative polyarthritis, Inflammation, Erosion lesion, 4-hydroxy-2-oxovalerate aldolase activity	Altered Intercellular Communication	Erosive osteoarthritis of the hand (EHOA) is thought to be an aggressive variant of hand osteoarthritis (HOA) characterised by prominent local inflammation and radiographic aspects of bone erosions in interphalangeal (IP) joints.	22401873
Chronic infectious disease, Inflammation, Epithelial ovarian cancer	Altered Intercellular Communication	The present study validates the theory of chronic infections and inflammation in the pathogenesis of epithelial ovarian cancer.	22402815
Inflammation, Dermatitis, Irritant	Altered Intercellular Communication	Genetic variations in genes coding for cytokines involved in skin inflammation may alter their expression, thus changing the susceptibility to irritant contact dermatitis (ICD).	22404198
Inflammation, Complication Aspects, Atherosclerosis, Communicable Diseases, Hepatitis C	Altered Intercellular Communication	Hepatitis C virus (HCV) infection is associated with systemic inflammation and metabolic complications that might predispose patients to atherosclerosis.	22404725
Inflammation	Altered Intercellular Communication	The presence of bowel inflammation and fistulas should not preclude such diagnosis.	22405176
Refractory anemias, Inflammation, Arthritis	Altered Intercellular Communication	In RA patients, chronic inflammation of this tendon or talonavicular joint arthritis can results in posterior tibial tendon rupture.	22405554
Refractory anemias, Rupture, Fibrinoid necrotizing inflammation	Altered Intercellular Communication	In a 61-year-old RA patient, ruptures of the posterior tibial tendon due to rheumatoid inflammation occurred bilaterally, with subsequent deviation and instability of the forefoot.	22405554
Neurogenic Inflammation	Altered Intercellular Communication	The aim of this investigation is to determine the correlation between neurogenic inflammation and nociception associated with OLP-R and OLP-E.	22406713
Inflammation, Leucocytic infiltrate	Altered Intercellular Communication	We found that 1) an increase in peripheral innervation was related to the size of the area of inflammatory cell infiltration from both OLP-R and OLP-E; 2) the pattern of PGP 9.5-immunoreactivity among OLP-R and OLP-E was not significantly different (P=0.23); and 3) the correlation between nociception and an increase in PGP 9.5-immunoreactivity was not found in OLP-E and in OLP-R. Our findings suggest that an increase in peripheral innervation may lead to increased inflammation, which is part of the immunopathogenesis of OLP.	22406713
Fibrosis Assessment	Altered Intercellular Communication	Hepatic allograft inflammation grade >=2 and fibrosis stage >=2 occurred in 221 (64%) and 140 (40%) patients, respectively.	22406819
Inflammation, Fibrosis Assessment, Cytomegalovirus	Altered Intercellular Communication	CMV disease was associated with increased risk of inflammation grade >=2 (RR, 3.40; P<0.001), and although not significant, with fibrosis stage >=2 (RR, 2.03; P=0.052).	22406819
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	As this classification does not consider segmental inflammation, backwash ileitis, or rectal sparing, an additional subgroup analysis was performed in 80 cases and 80 age- and sex-matched IBD controls, reviewing all endoscopy and pathology reports filed between 2000 and 2010.	22407885
Inflammation, Papilledema, Scotoma	Altered Intercellular Communication	Among the eyes with disc swelling, 13 eyes of 7 patients had visual field defects even after the inflammation subsided, and these patients were older, had a higher DM/DD ratio, and had a smaller C/D ratio than those without visual field defects.	22408010
Uveomeningoencephalitic Syndrome, Inflammation, Papilledema	Altered Intercellular Communication	The occurrence of disc swelling in VKH was significantly correlated with age and disc morphology, rather than the severity of inflammation.	22408010
ARCN1 gene, Inflammation, Muscular Atrophy	Altered Intercellular Communication	Oxidation levels of proteins, myosin heavy chain (MyHC) and myonuclei, superoxide anion, antioxidants, actin, creatine kinase, carbonic anhydrase-3, ubiquitin-proteasome system, redox-signalling pathways, inflammation and muscle structure, and damage were quantified in limb muscles of severe COPD patients with and without muscle wasting, and in sedentary controls.	22408199
Myositis	Altered Intercellular Communication	Muscle inflammation and glutathione levels did not differ between patients and controls.	22408199
Inflammation, Drug abuse, septic, Diabetes Mellitus	Altered Intercellular Communication	The source of the inflammation was septic lesions of the lower body, whereas the perdisposal factors were considered to be the diabetes mellitus, drug abuse and immunodeficiency.	22408805
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	The associations between inflammation, diabetes and insulin resistance remain controversial.	22409372
Inflammation, Vasculitis, CTCAE, Papilledema	Altered Intercellular Communication	When inflammation is present, it can be severe and frequently associated with other complications such vasculitis and papillitis.	22409567
Inflammation, Autoimmune Chronic Hepatitis, Insemination, Artificial, Homologous	Altered Intercellular Communication	To observe the expression change of signal regulatory protein alpha1 (SIRPalpha1) in autoimmune hepatitis (AIH) and approach the relationship between SIRPalpha1 and the extent of inflammation.	22409853
Inflammation, Ankylosis	Altered Intercellular Communication	Inhibition of inflammation but not ankylosis by glucocorticoids in mice: further evidence for the entheseal stress hypothesis.	22410100
Inflammation, Ankylosis, Spondylitis	Altered Intercellular Communication	Studies in the spontaneous ankylosis model in aging male DBA/1 mice and in patients with ankylosing spondylitis provide evidence that inflammation and new tissue formation leading to joint or spine ankylosis are likely linked but largely uncoupled processes.	22410100
Inflammation, Arthritis, Ankylosis	Altered Intercellular Communication	Here, we further investigated the relationship between inflammation and ankylosis by focusing on the early phase of the spontaneous arthritis model.	22410100
Inflammation, Ankylosis	Altered Intercellular Communication	Dexamethasone treatment did not affect incidence or severity of ankylosis, but led to an expected reduction in inflammation in the paws at week 15 as measured by PET tracer uptake.	22410100
Inflammation, Enthesitis, Ankylosis	Altered Intercellular Communication	BMP signaling may be a trigger for both inflammation and ankylosis in the spontaneous model of ankylosing enthesitis.	22410100
Inflammation, CNDP2 gene, Nerve Degeneration	Altered Intercellular Communication	Altogether, our findings support a key role of CNDP2 in PD neurodegeneration, by mechanisms that could involve oxidative stress, protein aggregation or inflammation.	22410244
Retinal Vasculitis	Altered Intercellular Communication	This case highlights the importance of considering connective tissue inflammatory conditions in any retinal vasculitis.	22410282
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Metabolic Syndrome X	Altered Intercellular Communication	Systemic inflammation has been suggested to be involved in the pathogenesis of chronic obstructive pulmonary disease (COPD) and metabolic syndrome.	22410468
Inflammation, Dystrophic calcification	Altered Intercellular Communication	Tonsilloliths are rare dystrophic calcification formed as a result of chronic inflammation of the tonsils.	22410514
Scleritis, Inflammatory disorder	Altered Intercellular Communication	To determine the clinical differences between sclerosing orbital inflammation (SOI) isolated to the orbit and SOI manifesting as part of systemic inflammatory disease.	22410659
Communicable Diseases, Inflammation, Acute infectious disease	Altered Intercellular Communication	Biomarkers of inflammation, including C-reactive protein (CRP) and a(1) -acid glycoprotein (AGP), have tremendous potential in anthropological, public health, and nutrition research as objective indicators of acute infection; however, their usage is limited by the lack of widely agreed upon, reliable cutpoints to define infection.	22411080
Carcinogenesis	Altered Intercellular Communication	These findings are consistent with research supporting the infectious/inflammation pathway in prostate carcinogenesis.	22411189
Inflammation, Breast Carcinoma, Fatigue	Altered Intercellular Communication	Fatigue, inflammation, and o-3 and o-6 fatty acid intake among breast cancer survivors.	22412148
Inflammation, Primary malignant neoplasm, Fatigue	Altered Intercellular Communication	Evidence suggests that inflammation may drive fatigue in cancer survivors.	22412148
Inflammation, Fatigue	Altered Intercellular Communication	Research in healthy populations has shown reduced inflammation with higher dietary intake of o-3 polyunsaturated fatty acids (PUFAs), which could potentially reduce fatigue.	22412148
Inflammation, Fatigue	Altered Intercellular Communication	Results link higher intake of o-3 PUFAs, decreased inflammation, and decreased physical aspects of fatigue.	22412148
ARCN1 gene, Airway structure	Altered Intercellular Communication	In subjects with COPD, nasal epithelial cells cannot substitute for in vitro bronchial epithelial cells in airway inflammation studies.	22412951
Exacerbation	Altered Intercellular Communication	Neutrophilic inflammation is prominent, worsened during infective exacerbations and is refractory to glucocorticosteroids (GCs).	22413009
Infertility, Tumor necrosis, Inflammation	Altered Intercellular Communication	In the testes of both infertile men and in a mouse model of inflammation associated infertility (aromatase-overexpressing transgenic mice), the fibrotic changes and increased numbers of tumour necrosis factor (TNF)-a-producing immune cells were shown to be associated with increased production of DCN.	22413766
Trismus, Inflammation, Toxic effect	Altered Intercellular Communication	Late toxicity occurred as grade 3 trismus in five and as grade 3 abacterial salivary gland inflammation in one patient, respectively.	22414284
Intraocular inflammation	Altered Intercellular Communication	Five cases of severe intraocular inflammation after intravitreal bevacizumab were documented.	22414958
Female Genital Diseases, Inflammation, Endometriosis, Atherosclerosis	Altered Intercellular Communication	Endometriosis, a chronic benign gynecological disorder, shows some characteristics, such as oxidative stress, systemic inflammation and a pro-atherogenic lipid profile, which could increase the risk of developing accelerated atherosclerosis.	22416009
Inflammation, Carotid Intima-Media Thickness, Atherosclerosis	Altered Intercellular Communication	The presence of subclinical atherosclerosis was investigated by ultrasound evaluation of common carotid intima-media thickness (ccIMT) and flow-mediated dilation (FMD); in addition, serum levels of lipids, inflammatory and coagulation parameters, as well as markers of endothelial inflammation and activation, were determined.	22416009
HD Term Type, Inflammation, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation, oxidative stress, and obesity are important features associated with pathogenesis of cardiovascular disease, a major contributor to the mortality of hemodialysis (HD) patients.	22417287
HD Term Type, Inflammation, Obesity	Altered Intercellular Communication	Thus, the purpose of this study was to analyze apelin plasma levels in HD patients and verify whether there is any relationship with inflammation, oxidative markers, and obesity.	22417287
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic Syndrome X, Cardiovascular Diseases	Altered Intercellular Communication	High sensitivity C-reactive protein (hs-CRP), a marker of systemic inflammation and a predictor of type 2 diabetes and cardiovascular disease, is associated with the metabolic syndrome and its separate components.	22417460
Uveal melanoma, Inflammation	Altered Intercellular Communication	A range of significantly elevated angiogenic, inflammatory, and chemotactic cytokines in eyes with uveal melanoma supports the link between inflammation and tumorigenesis.	22418780
Inflammation, Sleep Apnea, Obstructive, Psoriasis	Altered Intercellular Communication	In our study, we aimed to investigate the frequency of OSAS in patients previously diagnosed with psoriasis in order to investigate a potential association between chronic inflammation psoriasis and OSAS.	22418840
Hallucinations, Visual	Altered Intercellular Communication	The pathophysiology of visual hallucinations may involve enhanced serotonergic neurotransmission.	22419526
Rupture, Arteritis	Altered Intercellular Communication	Nonetheless, our findings suggest that imaging of coronary artery inflammation is feasible, and further work evaluating (18)F-FDG uptake in high-risk coronary plaques prior to rupture would be of great interest.	22419753
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Fibrinogen is a marker of systemic inflammation and may be important in the pathogenesis and progression of chronic obstructive pulmonary disease (COPD).	22419864
Pneumoconiosis due to talc, Inflammation, Pneumoconiosis	Altered Intercellular Communication	Talcosis, a granulomatous inflammation of the lungs caused by inhalation of talcum dust, is a rare form of pneumoconiosis.	22420484
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Periodontal Diseases	Altered Intercellular Communication	To determine the strength of association of type 2 diabetes mellitus and periodontal disease with the oral inflammatory burden, as assessed by markers of inflammation in saliva.	22420648
Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation and neurologic manifestations were controlled in all cases.	22420960
Intraocular Infection, Morbidity - disease rate, Inflammatory abnormality of the eye	Altered Intercellular Communication	Although ocular inflammation occurring after IOL implantation responds to corticosteroids, intraocular infections should always be taken into consideration to prevent severe ocular morbidity.	22421095
Rheumatoid Arthritis, Orchitis	Altered Intercellular Communication	Blockade of the interleukin-6 receptor (IL6R) with a monoclonal antibody (tocilizumab) licensed for treatment of rheumatoid arthritis reduces systemic and articular inflammation.	22421340
Inflammation, Rupture, Blood Clot, Plaque, Atherosclerotic, Embolism	Altered Intercellular Communication	Carotid artery-related stroke is largely an embolic disease that has been correlated with inflammation, plaque rupture, and thrombus formation in "vulnerable" atherosclerotic plaque.	22422179
Inflammation, Urinary Tract Physiology	Altered Intercellular Communication	Some lower urinary tract dysfunction (LUTD) subtypes may be associated with low-grade inflammation.	22422219
Granulomatous inflammation, Metallosis, Age related macular degeneration	Altered Intercellular Communication	ARMD is a spectrum of changes comprising of pure metallosis, ALVAL and granulomatous inflammation.	22422805
Prosthesis Failure, Necrosis	Altered Intercellular Communication	Lymphoid neogenesis documented in a variety of chronic inflammatory conditions most probably contributes to tissue necrosis and prosthetic failure seen in MoM hip arthroplasties.	22422805
Inflammation, Oligospermia	Altered Intercellular Communication	In addition, oligospermia, dilatation of the duct, and inflammation were frequently observed in the epididymides.	22423049
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Heightened levels of inflammation may be associated with an increased risk of depression, particularly among those with inflammatory medical conditions.	22424164
Chronic kidney disease stage 5, Inflammation, Kidney Failure, Chronic, Depression, CTCAE	Altered Intercellular Communication	Although elevated rates of both systemic inflammation and depression have been documented among patients with end stage renal disease (ESRD), the link between these factors has received little empirical evaluation.	22424164
Rheumatic inflammation, Failure (biologic function), Thickened, Congenital Abnormality	Altered Intercellular Communication	The major causes for failure of rheumatic mitral valve repair are the presence of ongoing rheumatic inflammation at the time of surgery, use of inappropriate techniques, technical failures requiring early reoperation, lack of concomitant ring annuloplasty, and progression of leaflet and chordal disease further resulting in more leaflet retraction, thickening, and deformity.	22424512
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	We tested whether diet-induced obesity, diabetes, and inflammation are associated with anti-bacterial IgG.	22424821
Appendage, Inflammation	Altered Intercellular Communication	Epiploic appendagitis is a rare, self-limiting inflammation of the epiploic appendices or omental appendices.	22424988
Inflammation, Thrombus, Ischemic stroke	Altered Intercellular Communication	The genetic basis of complex diseases like ischemic stroke probably consists of several predisposing risk factors, such as genes involved in inflammation and thrombotic pathways.	22425140
Inflammation, Paresthesia, Necrosis	Altered Intercellular Communication	Only transient complications of sclerotherapy were observed: local inflammation, perioral paresthesia in two patients, and necrosis of the mucosa of the cheek in one.	22425358
Inflammation, Disease remission, Insemination, Artificial, Homologous	Altered Intercellular Communication	However, we observed that the Treg frequency was significantly higher in those AIH patients with active disease than in those who were in a state of remission, suggesting that the Treg frequency may increase with the degree of inflammation.	22425700
Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is a multifactorial disorder with chronic inflammatory conditions in which immune cells play a significant role in its pathogenic process.	22426168
Inflammation	Altered Intercellular Communication	Oxidized-LDL (ox-LDL), high-sensitivity C-reactive protein (hs-CRP) and the soluble intracellular adhesion molecule (ICAM) were chosen as biomarkers for systemic inflammation and oxidative damage.	22426659
Pain Distress Question, Inflammatory abnormality of the eye	Altered Intercellular Communication	A 6-year-old child presented with watering in the right eye for 3 days without ocular inflammation or pain.	22427147
Inflammation, Sleep Disorders	Altered Intercellular Communication	We concluded that inflammation has a close relation with sleep disorders in hemodialysis patients.	22427289
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Because chronic obstructive pulmonary disease is characterized by low-grade systemic inflammation, we hypothesized that addition of inflammatory biomarkers to established predictive factors will improve accuracy.	22427534
Inflammation, Diabetic Retinopathy	Altered Intercellular Communication	Inflammation is a key causative factor in the pathogenesis of diabetic retinopathy.	22427566
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	We speculate that the increased expression of GPR109A and elevation of its ligand b-HB in diabetes are mechanisms by which the tissue attempts to fight inflammation in this disease.	22427566
Pleurisy, Pleural effusion associated with pulmonary infection	Altered Intercellular Communication	Hyaluronic acid (HA) is a component of extracellular matrix and may play a role in the pleural inflammation which is implicated in parapneumonic effusions.The aim of the current study was to investigate HA levels in serum and pleura in patients with parapneumonic effusions.	22428219
Inflammation	Altered Intercellular Communication	Matrix metalloproteinases (MMPs) induce leukocyte migration into inflammation sites that lead to either promotion or repression of inflammation by activating or inactivating cytokines.	22428754
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	Accumulating evidence suggests that inflammation may contribute to the development of BPH and LUTS.	22429766
Inflammation, Nocturia, Lower Urinary Tract Symptoms, Benign prostatic hypertrophy	Altered Intercellular Communication	To investigate the relationship between non-steroidal anti-inflammatory drug (NSAID) use and the incidence of benign prostatic hyperplasia (BPH)-related outcomes and nocturia, a lower urinary tract symptom (LUTS) of BPH, in light of accumulating evidence suggesting a role for inflammation in BPH/LUTS development.	22429766
Refractory Cytopenia of Childhood, Cystitis, Neoplasms	Altered Intercellular Communication	Up-regulated miRNA 15a can be measured in urine from patients with RCC but is nearly undetectable in oncocytoma, other tumors, and urinary tract inflammation.	22429968
Inflammation, immunoglobulin A	Altered Intercellular Communication	Chronic parodontit inflammation in elderly patients was found to be accompanied by inbalance of complement system; IgA (sIgA), IgA, IgG, IgM hyperproduction; the increase of IL-8, IL-1a concentration and decrease of IL-4 level; increase Hsp-70 antibodies.	22433635
PODXL2 gene, Inflammation, Gastroenteritis, Eosinophilic inflammation	Altered Intercellular Communication	Eosinophilic gastroenteritis (EG) is an inflammation of the digestive tract that is characterized by eosinophilic infiltration.	22433795
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Data of literature on the role of inflammation factors in the pathogenesis of stroke are presented.	22433805
Infarction, Inflammation	Altered Intercellular Communication	It has been shown that the activation of systemic inflammation and related oxidative stress recorded in the early acute phase of brain infarction needs pharmacological treatment.	22433805
Barrett Esophagus, Dysplasia, Esophagitis	Altered Intercellular Communication	Distribution of body fat and its influence on esophageal inflammation and dysplasia in patients with Barrett's esophagus.	22433923
Dysplasia, Esophagitis	Altered Intercellular Communication	We investigated the distribution of fat in subjects with BE and its association with esophageal inflammation and dysplasia.	22433923
Dysplasia, Esophagitis	Altered Intercellular Communication	Esophageal inflammation (based on a histologic score) and dysplasia grade were assessed from esophageal biopsies of BE cases by a gastrointestinal pathologist.	22433923
Dysplasia, Esophagitis	Altered Intercellular Communication	Visceral and GEJ fat were significantly greater in BE subjects with esophageal inflammation (compared with those without, P = .02) and high-grade dysplasia (compared with those without, P = .01), independent of BMI.	22433923
Dysplasia, Esophagitis	Altered Intercellular Communication	GEJ and visceral fat are associated with BE, and with increased esophageal inflammation and high-grade dysplasia in BE subjects, independent of BMI.	22433923
Liver carcinoma	Altered Intercellular Communication	A novel, externally validated inflammation-based prognostic algorithm in hepatocellular carcinoma: the prognostic nutritional index (PNI).	22433965
Inflammation, deficiency aspects	Altered Intercellular Communication	Inflammation was clearly associated with the observed TST deficiency.	22434643
Crohn Disease, Acute inflammation	Altered Intercellular Communication	Recent work provides evidence of a failure of acute inflammation in Crohn's disease (CD), and suggests that the primary defect operates at the level of the macrophage and cytokine release.	22434667
Inflammation, Bronchoconstrictor Agents	Altered Intercellular Communication	Although leukotriene D4 (LTD4) is a potent bronchoconstrictor, little is known about airway responsiveness to LTD4 in asthmatics with different inflammation phenotypes.	22435894
Inflammation, Fever, CTCAE, Abdominal guarding (finding)	Altered Intercellular Communication	There was no fever or muscular guarding, and no signs of inflammation in the blood screening.	22436521
Inflammation, Observation Method - Coagulation, Traumatic injury	Altered Intercellular Communication	Injured adult patients eligible for enrolment in the Activation of Coagulation and Inflammation in Trauma 2 study, and admitted to the intensive care unit between January 2008 and January 2010, were selected retrospectively for the study.	22437496
Osteopenia	Altered Intercellular Communication	Disuse is the primary cause for bone loss, although neural and hormonal changes may also contribute via different mechanisms.	22437628
Inflammation, Arteriosclerosis	Altered Intercellular Communication	Our results suggest that subjects who have mild inflammation related to arteriosclerosis have decreased regional gray matter volume in the posterior and lateral aspects of the left temporal cortex.	22438310
Inflammation	Altered Intercellular Communication	It is unclear whether these changes result from chronic inflammation or whether they represent early events in the gluten response.	22438948
ARCN1 gene, Inflammation	Altered Intercellular Communication	b2 long-acting and anticholinergic drugs control TGF-b1-mediated neutrophilic inflammation in COPD.	22440430
Cerebrovascular, "Alzheimers Disease	Altered Intercellular Communication	Early cerebrovascular inflammation in a transgenic mouse model of Alzheimer's disease.	22440674
Inflammation, Data types - Address, Nerve Degeneration	Altered Intercellular Communication	Inflammation contributes to neurodegeneration at later stages of AD, but it may also play a role in early disease pathogenesis.	22440674
Cerebrovascular, Dental Plaque, Data types - Address	Altered Intercellular Communication	We found that before plaque deposition, amyloid precursor protein (APP)/presenilin 1 (PSEN1) transgenic mice (PSAPP mice), a well-characterized model of AD, exhibit evidence of cerebrovascular inflammation.	22440674
Cerebrovascular	Altered Intercellular Communication	Our study indicates that MECA-32 may be a robust marker of cerebrovascular inflammation and compromised BBB integrity, triggered by soluble amyloid-b early in disease pathogenesis.	22440674
Pancreatitis, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Both GLP-1 receptor agonists and DPP-4 inhibitors are associated with increased levels of serum lipase more than serum amylase in many patients with type 2 diabetes, possibly suggesting the presence of pancreatic inflammation.	22440997
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Podocyte as a potential target of inflammation: role of pioglitazone hydrochloride in patients with type 2 diabetes.	22441004
Diabetes Mellitus, Non-Insulin-Dependent, Nephritis	Altered Intercellular Communication	Pioglitazone treatment revealed a podocyte-protective capacity in patients with type 2 diabetes, and the underlying mechanisms may be partly attributed to its effective suppression of excessive local renal inflammation.	22441004
Inflammation, Hypertensive (finding), Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Subclinical inflammation may be associated with delayed/inhomogeneous atrial activation in hypertensive patients affected by atrial fibrillation.	22441219
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	Inflammation may be implicated in the haemodynamic deterioration and in the development of complications in patients with cirrhosis.	22441510
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	High-sensitivity C-reactive protein (hsCRP) is a marker of low-grade inflammation, and predicts outcomes in patients at risk of ischaemic heart disease.	22441510
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	We investigated a possible association between markers of inflammation and splanchnic and systemic haemodynamics, complications and survival in patients with cirrhosis.	22441510
ARCN1 gene, Inflammation	Altered Intercellular Communication	Reduced nuclear factor-kB repressing factor: a link toward systemic inflammation in COPD.	22441735
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic systemic inflammation is implicated in the systemic manifestations and, probably, the excess mortality risk of chronic obstructive pulmonary disease (COPD).	22441735
ARCN1 gene, Inflammation	Altered Intercellular Communication	NRF expression is reduced in PBMCs of stable COPD patients, probably through oxidative stress, leading to increased production of IL-8/CXCL8 and potentially chronic systemic inflammation.	22441735
Airway structure, Allergic	Altered Intercellular Communication	Recent evidence shows that this treatment also improves airway inflammation in nonallergic patients.	22441741
Nephritis	Altered Intercellular Communication	Our data suggest that in the acute stage of the disease neutrophils may act as an important immediate-early innate source of IL-17 and may thereby initiate and promote ongoing renal inflammation.	22442208
Inflammation, diabetic	Altered Intercellular Communication	Systemic inflammation is thought to have a central role in diabetic long-term complications.	22442277
Data types - Address	Altered Intercellular Communication	Our results demonstrate increased IFN-g responses in skin of patients with AD and suggest involvement of multiple new apoptosis- and inflammation-related factors in the development of AD.	22445417
Intraocular inflammation	Altered Intercellular Communication	Upon starting anti-toxoplasmic therapy (ATT), her intraocular inflammation resolved with catastrophic damage to the disc and macula.	22446913
Inflammation, Carotid Stenosis, Dental Plaque	Altered Intercellular Communication	Our results show a close association between neovascularization, expression of angiogenic factors, inflammation, and plaque vulnerability in patients with advanced carotid stenosis.	22447000
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The developmental trajectory between early life stress and inflammation appears not to be mediated by metabolic syndrome associated factors in our sample.	22447087
Inflammation, Fibrosis Assessment, Hypertrophic Cardiomyopathy	Altered Intercellular Communication	Low-grade inflammation and the phenotypic expression of myocardial fibrosis in hypertrophic cardiomyopathy.	22447464
Inflammation, Fibrosis Assessment, Health maintenance, Hypertrophic Cardiomyopathy	Altered Intercellular Communication	To investigate the role of inflammation in the phenotypic expression of myocardial fibrosis in hypertrophic cardiomyopathy (HCM).	22447464
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Markers of inflammation and intracellular metabolism of neutrophils in patients with acute coronary syndrome and normal troponin T levels.	22448368
Inflammation, Acute Coronary Syndrome, Endothelial dysfunction	Altered Intercellular Communication	Markers of inflammation and intracellular metabolism of neutrophils were studied in 58 patients with acute coronary syndrome with different levels of troponin T. In patients with repeated coronary events within a year, more pronounced endothelial dysfunction associated with activation of oxygen-dependent metabolism of neutrophils and lipid peroxidation process was revealed at admission to the hospital.	22448368
Aneurysm, ASAH1 gene, Inflammation	Altered Intercellular Communication	Cerebral microdialysis probes were placed in brain parenchyma of the respective vascular territory of the aneurysm in 21 consecutive aSAH patients, enrolled in a prospective study on inflammation.	22449315
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Recent evidences suggest that inflammation contributes to the development and progression of osteoarthritis (OA).	22449335
Tumor necrosis, Leucocytic infiltrate, Data types - Address, Inflammation	Altered Intercellular Communication	Vascular endothelial growth factor (VEGF), transforming growth factor b (TGF-b), and tumor necrosis factor a (TNF -a) may play important roles in inflammation and angiogenesis through effects on inflammatory cell infiltration or neovascularization in AD pathogenesis.	22449478
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	It has been reported to be associated with inflammation and endothelial dysfunction.	22449661
Granulomatosis, Inflammation, Granulomatosis with polyangiitis, Systemic Vasculitis	Altered Intercellular Communication	A key feature of granulomatosis with polyangiitis (GPA; or Wegener's granulomatosis) is the granulomatous inflammation of the upper respiratory tract, which leads to the subsequent destruction of adjacent tissues.	22449947
Irvine-Gass Syndrome, Inflammation, Hyphema, Cataract	Altered Intercellular Communication	Twenty five-gauge group achieved a significantly lower anterior chamber inflammation and a lower incidence of postoperative cystoid macular edema (CME) (p=0.01), hyphema (p=0.000) and after cataract (p=0.000) than 20-gauge group.	22449995
Acute inflammation	Altered Intercellular Communication	The 25-gauge sutureless vitrectomy achieves rapid and higher visual improvement, less postoperative inflammation and complications than the 20-gauge vitrectomy in ERM surgery.	22449995
Inflammation	Altered Intercellular Communication	Taken together, these data suggest that valvular DNA-damage pathways may be associated with inflammation and the stenosis severity in tricuspid aortic valves.	22450322
Neurocognitive Disorders, Inflammation, Hand	Altered Intercellular Communication	In spite of antiretroviral therapy (ART), patients continue to be at risk for HIV-associated neurocognitive disorders (HAND), which might be related to persistence of inflammation.	22450616
Inflammation, liposarcoma, Pseudotumor	Altered Intercellular Communication	We believe that the inflammatory pseudotumor complicated in repairing the inflammation arising from the liposarcoma.	22450833
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Although appendicitis is one of the most common causes of emergency surgery, parasites are rarely found associated with inflammation of the appendix.	22450920
Inflammation	Altered Intercellular Communication	The findings suggest that YKL-40 might be implicated in the pathogenesis of the disease and could indicate the level of joint inflammation.	22451025
Inflammation, Dry cough	Altered Intercellular Communication	The 2 patients sought attention because of chronic dry cough associated with inflammation of unknown origin.	22451028
Seizures, Inflammation	Altered Intercellular Communication	Thirty-two patients with an exclusive (n=11) or predominant (n=21) seizure presentation in whom an autoimmune etiology was suspected (on the basis of neural autoantibody [91%], inflammatory cerebrospinal fluid [31%], or magnetic resonance imaging suggesting inflammation [63%]) were studied.	22451162
ARCN1 gene, Inflammation, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The objective of our study was to investigate whether the profile of eicosanoid lipid mediators in EBC can characterize the inflammation in asthma and chronic obstructive pulmonary disease (COPD).	22451217
Leukopenia, Septicemia	Altered Intercellular Communication	A significant influence on leukopenia and febrile septicemia has been shown for several comorbidities, especially chronic inflammation.	22451304
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	The mode of action of acetylcholinesterase inhibitors (AChEIs) in Alzheimer's disease (AD) is mainly by potentiating neuronal transmission.	22451323
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We found an association between donor liver fibrosis and patient survival (p = 0.016) as well as between graft survival and portal inflammation in the donor liver (p = 0.026).	22452366
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histopathological features, especially portal inflammation and stage of fibrosis, in the donor liver may deleteriously affect graft and patient survival following HCV-related liver transplantation.	22452366
Inflammation	Altered Intercellular Communication	Humoral mediators of inflammation, in particular the complement system, have been described to play an important role in atherogenesis.	22452399
glycation, Pneumonitis	Altered Intercellular Communication	Soluble receptor for advanced glycation end products (sRAGE) is present at high concentrations in the lungs of children and varies with age and the pattern of lung inflammation.	22452564
glycation, Inflammation	Altered Intercellular Communication	The soluble receptor for advanced glycation end products (sRAGE) plays an important role in inflammation.	22452564
Inflammation, Subarachnoid Hemorrhage	Altered Intercellular Communication	Repeated cranial CT did not show subarachnoid hemorrhage; CSF examination showed neither xanthochromia nor inflammation.	22453044
Inflammation, Fever of Unknown Origin, Fever, CTCAE, Vasculitis, CTCAE	Altered Intercellular Communication	PET/CT is starting to play an important role in evaluating fever of unknown origin (FUO), due to its ability to localize and delineate areas of high metabolic activity, such as neoplastic proliferation and inflammation, including vasculitis.	22453531
Stomach Carcinoma, Neoplasms	Altered Intercellular Communication	Chronic allergic-like inflammation in the tumor stroma of human gastric carcinomas: an ultrastructural study.	22455876
Inflammation, Intradermal Route of Drug Administration	Altered Intercellular Communication	Values either were adjusted for inflammation [as measured by C-reactive protein (> 5 mg/L) and a(1)-acid glycoprotein (> 1 g/L) before applying cutoffs for ID] or were unadjusted.	22456661
Inflammation, Intradermal Route of Drug Administration	Altered Intercellular Communication	TfR better estimates the prevalence of ID in preschoolers than do ferritin, ZP, and the TfR/ferritin index on the basis of multiple indexes in a high inflammation, resource-poor setting.	22456661
HD Term Type, Inflammation	Altered Intercellular Communication	VDRA supplementation may suppress chronic inflammation and have some advantage for mortality of HD patients with vitamin D deficiency.	22457088
Alzheimers Disease", Inflammation	Altered Intercellular Communication	Inflammation of the brain is strongly implicated in Alzheimer's disease which could be enhanced by systemic inflammation.	22458804
Inflammation, Periodontitis, "Alzheimers Disease	Altered Intercellular Communication	Periodontitis being a chronic inflammatory condition, which can cause systemic inflammation, the question is whether chronic periodontitis can initiate or hasten the rate of progression of Alzheimer's disease in susceptible individuals.	22458804
Inflammation, Periodontitis, "Alzheimers Disease	Altered Intercellular Communication	Periodontitis being a chronic inflammatory condition, which can cause systemic inflammation, the question is whether chronic periodontitis can initiate or hasten the rate of progression of Alzheimer's disease in susceptible individuals.	22458804
ARCN1 gene, Inflammation	Altered Intercellular Communication	Effect of bronchial colonisation on airway and systemic inflammation in stable COPD.	22458940
Bronchial brand of guaifenesin-theophylline, Inflammation, ARCN1 gene	Altered Intercellular Communication	The objective of this study was to determine the relationships between bronchial colonisation and both bronchial and systemic inflammation in stable COPD.	22458940
Inflammation, Lymphoma	Altered Intercellular Communication	The main reason for the development of these cysts might be the accompanying inflammation of the lymphoma.	22459556
Asthmatic Airway Remodeling	Altered Intercellular Communication	Asthma is common in elite canoe and kayak athletes, and classical signs of asthmatic airway inflammation are also found in asymptomatic athletes.	22459716
Inflammation, Albuminuria, Functional Disability, Cardiovascular Diseases	Altered Intercellular Communication	Chronic inflammation, albuminuria, and functional disability in older adults with cardiovascular disease: the National Health and Nutrition Examination Survey, 1999-2008.	22460050
Disability, Inflammation, Albuminuria	Altered Intercellular Communication	We found combined association of inflammation and albuminuria with disability and with metabolic risks.	22460050
Disability, Inflammation, Albuminuria	Altered Intercellular Communication	There is a combined association of inflammation and albuminuria on multiple domains of disability and metabolic risks, suggesting the presence of elevated UACR may amplify the association of inflammation with disability and with metabolic risk in older adults living with CVD.	22460050
Heart failure	Altered Intercellular Communication	Heart failure and malnutrition/inflammation are prognostic factors related to mortality in these patients on chronic hemodialysis.	22460181
Sepsis, Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	Asymmetric dimethylarginine was decreased in pediatric sepsis and was inversely associated with inflammation and organ dysfunction.	22460770
Inflammation, Prostate, Prostate carcinoma	Altered Intercellular Communication	Inflammation and preneoplastic lesions in benign prostate as risk factors for prostate cancer.	22460812
Inflammation, Prostatic Intraepithelial Neoplasias, Atrophic	Altered Intercellular Communication	Benign changes ranging from atrophy and inflammation to high-grade prostatic intraepithelial neoplasia (HGPIN) are common findings on prostate core needle biopsies.	22460812
Inflammation, Atrophic, Prostate carcinoma	Altered Intercellular Communication	Although atrophy and inflammation may be precursors of prostate cancer, only HGPIN is currently recommended to be included in surgical pathology reports.	22460812
Inflammation, Atrophic	Altered Intercellular Communication	The initial benign specimen was reviewed for presence of HGPIN, atrophy (simple, lobular, and partial) and inflammation (glandular and/or stromal).	22460812
Inflammation, Atrophic, Prostate carcinoma	Altered Intercellular Communication	In a model adjusted for prostate-specific antigen (PSA) level at cohort entry and inflammation, simple atrophy was associated with a 33% increased prostate cancer risk that was marginally significant (P=0.03).	22460812
Cerebrovascular accident	Altered Intercellular Communication	Carotid plaque inflammation on 18F-fluorodeoxyglucose positron emission tomography predicts early stroke recurrence.	22461139
Rupture, Thromboembolism	Altered Intercellular Communication	Current carotid imaging techniques rely on estimating plaque-related lumen narrowing but do not evaluate intraplaque inflammation, a key mediator of plaque rupture and thromboembolism.	22461139
Carotid Stenosis, Cerebrovascular accident	Altered Intercellular Communication	In recently symptomatic carotid stenosis, inflammation-related FDG uptake was associated with early stroke recurrence, independent of the degree of stenosis.	22461139
Diabetic Nephropathy, Inflammation, glycation	Altered Intercellular Communication	Effects of sevelamer on HbA1c, inflammation, and advanced glycation end products in diabetic kidney disease.	22461535
Inflammation	Altered Intercellular Communication	Increased inflammation and oxidative stress may be caused by proteins and lipids modified by cytotoxic advanced glycation end products (AGEs) in food.	22461535
Inflammation, Kidney Diseases, Diabetes Mellitus	Altered Intercellular Communication	Sevelamer carbonate significantly reduces HbA1c, fibroblast growth factor 23, lipids, and markers of inflammation and oxidative stress, and markedly increases antioxidant markers, independently of phosphorus in patients with diabetes and early kidney disease.	22461535
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Research into the etiology of breast cancer has recently focused on the role of the immunity and inflammation.	22461912
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The proinflammatory cytokines IL-17A and IL-17F can mediate inflammation and cancer.	22461912
Troponin T, Cardiac Muscle, Inflammation	Altered Intercellular Communication	Laboratory investigations revealed normal serum cardiac troponin T and serum potassium, and absence of inflammation signs.	22462353
Inflammation, Fibrosis Assessment, Atherosclerotic aneurysm	Altered Intercellular Communication	CT findings, laboratory tests and finally, histopathologic examination showed atherosclerotic aneurysm without inflammation and retroperitoneal fibrosis.	22462354
Chronic lymphocytic inflammation, Polyarteritis Nodosa	Altered Intercellular Communication	It was seen in a variable number of small- to medium-sized parenchyma arteries with segmental to transmural lymphocytic inflammation, within the morphological spectrum of a polyarteritis nodosa (PAN)-like lesion seen at the periphery of BPH nodules.	22462607
Inflammation, Dental Plaque	Altered Intercellular Communication	Chronic inflammation was found superficially in 59/125 plaques (47%) and deeply inside the plaque tissue in 103/125 plaques (83%).	22463585
Inflammation, Hemorrhage	Altered Intercellular Communication	Moreover, microvascular CD105 positivity correlated positively with plaque haemorrhage and deeply seated plaque inflammation.	22463585
Inflammation, Hemorrhage, Coronary Arteriosclerosis	Altered Intercellular Communication	Plaque inflammation and haemorrhages can be found at a high frequency throughout the coronary artery system of elderly patients with multivessel coronary atherosclerosis.	22463585
Inflammation, Herpetic Gastritis	Altered Intercellular Communication	Most patients with herpetic scleritis presented with acute (85.7%) and unilateral (80%) scleral inflammation.	22463821
Inflammation, Primary malignant neoplasm, Cancer Pain	Altered Intercellular Communication	Although recent studies have suggested a relationship between single nucleotide polymorphisms (SNPs) in several cytokine and inflammation genes with cancer prognosis, associations with cancer pain are not clear.	22464751
Inflammation, Dental Plaque, Atherosclerotic lesion	Altered Intercellular Communication	Inflammation plays an essential role in the development and progression of atherosclerotic lesions, and plaque disruption.	22465044
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Systemic inflammation, including fever, was a characteristic manifestation of the AEs in CTD patients, particularly those with anti-RNP antibody.	22466117
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Systemic inflammation, including fever, might be a characteristic feature of the AEs in CTD patients, particularly those with anti-RNP antibody.	22466117
Inflammation	Altered Intercellular Communication	Subsequently in reproductive age they are developed usually against hypoestrogenomia; however the physiological reduction in estrogen levels during menopause by itself contributes to impairment of metabolism and intensification of inflammation (inflammatory markers CPR, ALT), oxidative stress (O(2)(-), LOO*), hipoxia (HBNO) and all related compititions (increase vascular resistence, disorders in oxygen suplay in tissue and hypoxic compititions of there metabolism).	22466534
Inflammation, Myocardial	Altered Intercellular Communication	Leukocyte filtration of blood cardioplegia attenuates myocardial damage and inflammation.	22466697
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	We started steroid administration after the fourth PCI to reduce inflammation due to autoimmunity.	22466830
Inflammation, Malnutrition, palladium, Hypertension, CTCAE, Chronic Kidney Diseases	Altered Intercellular Communication	Overhydration as assessed by ECW/TBW is prevalent in adult PD patients, and is associated with loss of residual renal function, inflammation, malnutrition and hypertension - as assessed by antihypertensive medications.	22466994
Inflammation, Cachexia, Chronic Kidney Diseases	Altered Intercellular Communication	As this was a retrospective cross-sectional audit, whether loss of residual renal function, inflammation, and protein energy wasting lead to volume expansion remains to be determined in prospective longitudinal studies.	22466994
Inflammation, Perforation (observation)	Altered Intercellular Communication	In order to avoid imminent perforation, a hemicolectomy became necessary, and immediately the symptoms and inflammation markers normalized rapidly.	22467540
Inflammation, BRCA1 wt Allele	Altered Intercellular Communication	We assume that the severe inflammation was caused by an immune restoration inflammatory syndrome (IRIS).	22467540
Inflammation, Failure, pathologic fistula	Altered Intercellular Communication	Postoperative CD (pouch inflammation into the afferent limb or pouch fistula) or pouch failure (need for permanent diversion) were assessed.	22467562
Inflammation	Altered Intercellular Communication	Afferent limb inflammation developed in three (50%) of the six patients with pANCA+/OmpC- expression compared to none of the 11 patients without this serologic profile (P = 0.03).	22467562
Abnormal circulating valine concentration, Inflammation	Altered Intercellular Communication	Metabolic abnormality and systemic inflammation may be the risk factors.	22467841
Inflammation	Altered Intercellular Communication	The aspirin-induced bronchospasm is mediated by mast cell and eosinophilic inflammation.	22468095
Inflammation, Malnutrition	Altered Intercellular Communication	Malnutrition and inflammation are related to high rates of morbidity and mortality in hemodialysis patients.	22468100
Deposition	Altered Intercellular Communication	Kidney biopsy showed mesangial proliferation and IgA deposits with tubulointerstitial inflammation.	22468111
Inflammation, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	In men, obesity and the metabolic syndrome are accompanied by decreased testosterone levels, but little is known about the associations between visceral adipose tissue (VAT), VAT-related inflammation and sex steroids.	22469460
Inflammation, Hypogonadism, Metabolic Syndrome X	Altered Intercellular Communication	The significant inverse association between IL-6 and T suggests an important role of low-grade visceral fat inflammation in the central hypogonadism associated with the metabolic syndrome.	22469460
Inflammation, Tumor necrosis, Diverticular Diseases	Altered Intercellular Communication	Inflammation occurs in diverticular disease (DD), but there is little information on inflammatory cytokines such as tumour necrosis factor a (TNF-a).	22469482
Inflammation, Data types - Address	Altered Intercellular Communication	In particular, it appears to be overexpressed in DD with inflammation (AUD and SUDD) compared with DD without (AD).	22469482
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Fatigue	Altered Intercellular Communication	Fatigue symptoms relate to systemic inflammation in patients with type 2 diabetes.	22469909
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Fatigue	Altered Intercellular Communication	Chronic inflammation represents one characteristic of type 2 diabetes that may contribute to fatigue symptoms.	22469909
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Fatigue	Altered Intercellular Communication	These findings indicate that systemic low-grade inflammation relates to fatigue symptoms in patients with type 2 diabetes and suggest the involvement of inflammatory processes in the pathophysiology of diabetes-related fatigue.	22469909
Inflammation, Pain Distress Question	Altered Intercellular Communication	The cause is secondary to microabrasive wear and shedding of any portion of the prosthesis, and the microscopic foreign bodies activate inflammation which can lead to pain.	22470793
palladium, Tumor necrosis, Inflammation, Atherosclerosis	Altered Intercellular Communication	Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) can counteract inflammation and atherosclerosis, both common causes of morbidity in peritoneal dialysis (PD) patients.	22471587
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation may be a mechanism linking socioeconomic position (SEP) with cardiovascular disease.	22472036
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	A growing body of evidence indicates that inflammation is one of the earliest neuropathological events in Alzheimer's disease.	22472085
Inflammation	Altered Intercellular Communication	A higher concentration of CD34(+) cells and a lower degree of inflammation are associated with better clinical therapeutic responses.	22472173
Inflammation, Metabolic Diseases, Injury of liver	Altered Intercellular Communication	Associations between markers of liver injury and cytokine markers for insulin sensitivity and inflammation in middle-aged Japanese men not being treated for metabolic diseases.	22472283
Gastrointestinal Stromal Tumors, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Pathological examination revealed four cases of gastrointestinal stromal tumor and one case of inflammatory fibrosis caused by nonspecific inflammation.	22472403
Inflammation, Electrocardiogram: myocardial infarction (finding), Respiratory Failure, Pulmonary Edema, CTCAE	Altered Intercellular Communication	The role of inflammation associated with pulmonary edema as a cause of acute respiratory failure post-acute myocardial infarction remains to be determined.	22473400
Inflammation	Altered Intercellular Communication	Interleukin (IL)-22 is known to play a key role in promoting antimicrobial immunity, inflammation, and tissue repair at barrier surfaces by binding to the receptors, IL-10R2 and IL-22R1.	22473749
Inflammation, Weight decreased, Cachexia	Altered Intercellular Communication	We analyzed 129 single nucleotide polymorphisms (SNPs) in 80 genes for association with cachexia based on degree of weight loss (>5, >10, >15%) as well as weight loss in the presence of systemic inflammation (C-reactive protein, > 10 mg/l).	22473907
Malignant neoplasm of liver, Inflammation, Fibrosis Assessment, Hepatocarcinogenesis	Altered Intercellular Communication	The results showed that the altered genes in FXR(-/-) livers were mainly related to metabolism, inflammation, and fibrosis, which suggest that hepatocarcinogenesis in FXR(-/-) mice recapitulated the progression of human liver cancer.	22474109
diabetic	Altered Intercellular Communication	In conclusion, circulating progenitor cells of diabetic patients show a phenotypic drift toward a pro-calcific phenotype that may be driven by inflammatory signals.	22474430
Inflammation, Aortic valve calcification, Aortic Valve Stenosis	Altered Intercellular Communication	Aortic valve stenosis (AS) is an actively regulated pathobiological process which has an inflammation origin, and manifests as an accumulation of lipids and, ultimately, calcification of the aortic valve tissue.	22474738
Inflammation, Arteriopathic disease, Corneal Endothelial Cell Loss	Altered Intercellular Communication	We hypothesised that chronic condition of arterial disease engenders inflammation and endothelial damage in response to circulating cytokines released in the blood stream of PAD patients.	22475098
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Effective management of patients affected by retroperitoneal fibrosis (RPF) is an important issue because of lack of relevant parameters to objectively assess the degree of inflammation.	22475894
Inflammation, Bursitis	Altered Intercellular Communication	We propose diffuse uptake may reflect ligament inflammation with focal uptake in adjacent interspinous bursitis.	22475905
Esophagitis	Altered Intercellular Communication	All patients underwent an upper endoscopy to determine if esophageal inflammation was present or absent.	22476040
Inflammation, Pancreatic carcinoma	Altered Intercellular Communication	Comparison of the prognostic values of various inflammation based factors in patients with pancreatic cancer.	22476808
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Correlations between serum inflammation factors and left ventricular remodeling in acute ST segment elevation myocardial infarction.	22476992
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	To investigate the changes and correlations of the serum inflammation factors levels and left ventricular (LV) structure and function in patients with acute ST segment elevation myocardial infarction (STEMI).	22476992
Optic Neuritis, Optic perineuritis	Altered Intercellular Communication	Inflammation of the optic nerve (optic neuritis) and its sheath (optic perineuritis) can have similar initial clinical presentations.	22477734
Lynch Syndrome, Colorectal Carcinoma	Altered Intercellular Communication	Our study demonstrates that colorectal carcinoma is not infrequently diagnosed in patients <=40 years of age and is not frequently the result of underlying Lynch syndrome or associated with other cancer-predisposing genetic conditions or chronic inflammatory conditions.	22481281
Inflammation	Altered Intercellular Communication	Association between butyrylcholinesterase activity and low-grade systemic inflammation.	22481455
Inflammation, Acute inflammation	Altered Intercellular Communication	In male patients with subclinical chronic inflammation and hsCRP concentrations < 1 mg/L, a significant positive correlation was observed between BChE and hsCRP (p < 0.02); however, for hsCRP concentrations > 3 mg/L, the correlation between these variables in both sexes becomes significantly negative (p < 0.001), as in patients with acute inflammation (hsCRP > 10 mg/L).	22481455
Inflammation	Altered Intercellular Communication	The liver production of BChE and albumin occurs in a coupled fashion, and these biochemical variables may be considered as negative inflammatory reactants, whose serum levels are inversely associated with the increasing degree of subclinical inflammation.	22481455
Cholesteatoma, Inflammation	Altered Intercellular Communication	The middle ear cholesteatoma, an aural epidermal pathology characterized by keratinocyte hyperproliferation and chronic inflammation, may represent a model condition to study the epithelial-mesenchymal interactions.	22481617
Borrelia Infections, Inflammation, Tularemia, Tick-Borne Lymphadenopathy	Altered Intercellular Communication	However, resistance to antibiotics and the absence of inflammation militated against this diagnosis, and other possible diagnoses such as a tick-borne lymphadenopathy (TIBOLA), borreliosis and tularaemia were discussed.	22482480
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Angiopoietin-2 (Angpt2) has been implicated in the mediation and regulation of angiogenesis and inflammation which are believed to be critical mechanisms in the pathogenesis of both abdominal aortic aneurysm (AAA) and cardiovascular events.	22483260
Cessation of life, Inflammation	Altered Intercellular Communication	Given that the literature suggests a strong link between social relationships and mortality, and that inflammation plays an important role in the leading causes of death, we had expected to find consistent and moderately strong associations between social relationships and inflammatory markers.	22483707
Tolosa-Hunt Syndrome, Inflammation, Methylated spirit	Altered Intercellular Communication	Tolosa-Hunt syndrome (THS), a nonspecific chronic inflammation of the cavernous sinus, is a rarely needed surgical manipulation, even for diagnosis, because corticosteroid therapy is markedly effective against this condition.	22484067
Inflammatory abnormality of the eye, diabetic	Altered Intercellular Communication	Patients with ocular inflammation followed at 5 United States tertiary centers that initially were neither diabetic nor taking hypoglycemic medications.	22484116
Inflammatory abnormality of the eye	Altered Intercellular Communication	These results suggest that the absolute risk of corticosteroid-induced hyperglycemia that is detected and treated with hypoglycemic therapy in the tertiary ocular inflammation setting is low (an excess cumulative risk on the order of 1% within 1 year), although on a relative scale it is approximately 4.4-fold higher than in patients not treated with oral corticosteroids.	22484116
Intraocular inflammation	Altered Intercellular Communication	Optical coherence tomography (OCT) revealed a CMO with a central thickness of 561 mm OD and 488 mm OS; there were no signs of intraocular inflammation.	22484725
Choroiditis	Altered Intercellular Communication	In order to understand the properties of taxane drug-induced cystoid macular oedema (TDICMO) we compared the spectral OCT findings of our case to an inflammation-induced CMO of equal thickness and to a case of multifocal choroiditis.	22484725
Choroiditis	Altered Intercellular Communication	In contrast to inflammation-induced CMO where the four external bands were well identified, there was attenuation of these bands in TDICMO but no disruption of the layers as seen in multifocal choroiditis, indicating that the fluid in TDICMO had a high viscosity producing a shadow underneath.	22484725
Inflammation, Tumor necrosis, Inflammatory abnormality of the eye	Altered Intercellular Communication	Several soluble mediators of inflammation such as tumor necrosis factor alpha (TNF-a) have been implicated in the pathogenesis of ocular inflammation.	22484726
Carcinoma, Chronic inflammation	Altered Intercellular Communication	Although the colonoscopic examination was highly suggestive of a carcinoma, the histopathological examinations were consistent with chronic inflammation.	22486169
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Cytokines from different T helper (Th) cell subsets are elevated in inflamed mucosa of patients with ulcerative colitis (UC), contributing to the inflammation.	22486187
Inflammation	Altered Intercellular Communication	Effector memory T-helper (Th)17 (Th17(EM)) cells are thought to be essential for inflammation in Th17-mediated diseases, but have not been studied in detail.	22486269
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	Such upper gastrointestinal inflammation appears to be particularly common in patients with Crohn's disease.	22486730
Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	T2D nonnephrotic patients with glomerular filtration rate (GFR) >30 ml/min and without acute cardiovascular/inflammatory conditions were included.	22486808
Granuloma, Inflammation, Thick, Ulcerative Colitis	Altered Intercellular Communication	Human CD tissues typically exhibited destructive full thickness enteritis with severe lympho-plasma infiltration and scattered additional granulomas; UC lesions exhibited much less inflammation than CD lesions.	22486997
Inflammation, Appendix Perforation, CTCAE	Altered Intercellular Communication	Histolopathologic examination confirmed appendiceal perforation with focal inflammation secondary to a foreign body.	22487649
Inflammation, Sleep Apnea, CTCAE, Endothelial dysfunction, Cerebrovascular accident	Altered Intercellular Communication	Biomarkers of inflammation and endothelial dysfunction in stroke with and without sleep apnea.	22488018
Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis	Altered Intercellular Communication	The inflammatory bowel diseases (IBD), Crohn's disease (CD), and ulcerative colitis (UC), are chronic inflammatory conditions of the gastrointestinal tract whose pathogenesis is not completely understood.	22488632
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Neither steatosis nor inflammation had significant influence on HVRI-based estimation of fibrosis (1.45 +- 0.2; 1.26 +- 0.05; 1.06 +- 0.06; 0.87 +- 0.08; 0.46 +- 0.11 for F0-FIV, respectively).	22488634
Inflammation, Phlebitis of portal vein, Appendicitis, CTCAE, Diverticulitis, Phlebitis	Altered Intercellular Communication	Pylephlebitis is a very rare and dangerous complication of inflammatory abdominal processes, mainly appendicitis (1) and diverticulitis (2).We describe a case of peridiverticular inflammation leading to a extensive phlebitis of the adjacent sigmoid vein, extending to the inferior mesenteric vein up to the proximal portal vein, with distal embolus into the left portal vein.	22489402
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Systemic disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a complex systemic disorder characterized by both local pulmonary and systemic inflammation.	22489883
Ocular Hypertension, Inflammation	Altered Intercellular Communication	Benzalkonium chloride induces anterior chamber inflammation in previously untreated patients with ocular hypertension as measured by flare meter: a randomized clinical trial.	22489894
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Fibrinogen is a marker of systemic inflammation and may represent an important biomarker for the progression of chronic obstructive pulmonary disease (COPD).	22489912
Inflammation, Dental Plaque, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	An accepted hypothesis states that coronary atherosclerosis (CA) is initiated by endothelial dysfunction due to inflammation and high levels of LDL-C, followed by deposition of lipids and macrophages from the luminal blood into the arterial intima, resulting in plaque formation.	22490844
Inflammation, Atherosclerosis	Altered Intercellular Communication	According to this alternative proposal, coronary atherosclerosis is not related to inflammation and can occur in individuals with normal circulating levels of LDL, consistent with research findings.	22490844
Corneal endotheliitis, Inflammation	Altered Intercellular Communication	Corneal endotheliitis was not only the inflammation of endothelium, but also varied pathological changes of all layer of the cornea.	22490910
Diffuse Axonal Injury, Inflammation, Neuronal loss in central nervous system, Glycoproteins, Kearns-Sayre syndrome	Altered Intercellular Communication	Myelin-associated glycoprotein loss in Kearns-Sayre syndrome was associated with oligodendrocyte loss and nuclear translocation of apoptosis-inducing factor, whereas inflammation, neuronal loss, and axonal injury were minimal.	22491194
Central nervous system demyelination, Inflammation	Altered Intercellular Communication	Primary mitochondrial respiratory chain defects affecting the white matter, and unrelated to inflammation, are associated with MAG loss and central nervous system demyelination.	22491194
Inflammation, Edema, Chronic iridocyclitis	Altered Intercellular Communication	To investigate the adverse ocular effects of intravitreal ketorolac (4 mg) in patients with chronic uveitis and complications of chronic inflammation (macular edema).	22491916
Inflammation, septic	Altered Intercellular Communication	Septic patients with systemic inflammation and enhanced thrombin generation (n=60) exhibited increased MMP-10 and soluble CD40L levels associated with adverse clinical outcome.	22492089
Degenerative polyarthritis, Inflammation, Traumatic injury	Altered Intercellular Communication	Synovial inflammation, a feature of both osteoarthritis (OA) and meniscal injury, is hypothesized to be triggered in part via stimulation of Toll-like receptors (TLRs).	22492243
Inflammation	Altered Intercellular Communication	A 7-d consumption of red orange juice ameliorates endothelial function and reduces inflammation in nondiabetic subjects with increased cardiovascular risk.	22492368
Inflammation	Altered Intercellular Communication	However, during conditions of stress, such as inflammation, arginine availability can become limited, which may lead to a nonunion as a result of insufficient callus formation.	22492379
Inflammation	Altered Intercellular Communication	Although the overall contribution of this process to the underlying mechanisms for AS disease development remains unresolved, these observations suggest that modification of Sirt1 expression and/or activity could represent a novel approach against inflammation in AS.	22493735
Keratitis	Altered Intercellular Communication	Prolonged corneal inflammation associated with TSPK can cause visually significant scarring of the anterior corneal stroma.	22495026
Inflammation	Altered Intercellular Communication	The stronger associations in women suggest that sex differences might exist in the complex interplay between BP and inflammation.	22495106
Inflammation, Chronic heart failure	Altered Intercellular Communication	Such categories have been mainly designed by matching different molecules levels to different pathophysiological stages of chronic heart failure, and comprise biomarkers of inflammation, oxidative stress, extracellular-matrix remodeling, neurohormones, myocte injury and stress, with an additional group of new biomarkers not yet fully characterized.	22495170
Inflammation, Chronic heart failure	Altered Intercellular Communication	Such categories have been mainly designed by matching different molecules levels to different pathophysiological stages of chronic heart failure, and comprise biomarkers of inflammation, oxidative stress, extracellular-matrix remodeling, neurohormones, myocte injury and stress, with an additional group of new biomarkers not yet fully characterized.	22495170
Inflammation, Chronic disease	Altered Intercellular Communication	We also hypothesized an association of MPO with markers of other chronic diseases involving inflammation.	22495256
Inflammation, Myocardial Ischemia	Altered Intercellular Communication	However, the results support the third hypothesis and previously reported view that MPO is a marker of inflammation in patients of ischemic heart disease.	22495256
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is critical for atherosclerosis development and may be a target for risk-reduction therapy.	22496207
Inflammation	Altered Intercellular Communication	The presence of low-grade inflammation and absence of positive affect, rather than presence of negative affect, may be important determinants of subjective health.	22496462
Airway structure, Allergy - Charge Type Reason	Altered Intercellular Communication	A very significant finding was that most allergy sufferers may have lower airway inflammation.	22496703
Airway structure	Altered Intercellular Communication	A better diagnosis of lower airway inflammation could be substantial in the management of these patients.	22496703
Inflammation, Endothelial dysfunction, diabetic, Atherosclerosis	Altered Intercellular Communication	Endothelial dysfunction is a common feature in type-2 diabetic patients and is associated with inflammation, increased levels of circulating soluble adhesion molecules and atherosclerosis.	22497223
Inflammation, Cachexia	Altered Intercellular Communication	Nearly all forms of cachexia are closely associated with chronic inflammation and elevated levels of inflammatory and pro-inflammatory circulating factors, including C-reactive protein (CRP), which is considered a valid laboratory and clinical marker.	22497530
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by inflammation of lung parenchyma and pulmonary hypoxemia with a proven systemic component.	22497562
Kidney Failure, Chronic, Fibrosis Assessment, Hepatitis C, Hepatitis	Altered Intercellular Communication	We compared the degree of liver inflammation and fibrosis in AA and CA patients with HCV infection, with and without ESRD.	22497817
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Specimens were graded for inflammation and fibrosis using Knodell histological activity index.	22497817
Renal Insufficiency, Fibrosis Assessment	Altered Intercellular Communication	Patients with renal impairment had lower mean serum transaminases, a higher mean serum alkaline phosphatase levels (all P < 0.0001) and less hepatic necro-inflammation (Knodell histological activity index -I, II and III; P < 0.05) and fibrosis (Knodell histological activity index -IV; P < 0.0001).	22497817
Kidney Failure, Chronic, Fibrosis Assessment, Hepatic inflammation, Kidney Diseases	Altered Intercellular Communication	Thus, HCV patients with ESRD had a lower degree of hepatic inflammation and fibrosis compared to those without renal disease, independent of race.	22497817
APP gene, Aortic Aneurysm, Abdominal, Acute and chronic inflammation	Altered Intercellular Communication	Abdominal aortic aneurysm (AAA) is associated with chronic mural inflammation and a pro-thrombotic diathesis.	22497884
Inflammation	Altered Intercellular Communication	Cytology of the biopsy demonstrated benign T-lymphocytes and histiocytes suggestive of mild chronic inflammation only.	22498134
Inflammation	Altered Intercellular Communication	Clinical evaluation of disease activity is often difficult, because most patients develop recurrent inflammation while receiving corticosteroid treatment.	22498333
Inflammation	Altered Intercellular Communication	FDG-PET/CT is useful for detection of active inflammation not only in patients with active TA before treatment but also in relapsing patients receiving immunosuppressive agents.	22498333
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Overall, loss of reticulin is more common and more extensive with marked fatty change and does not seem to be linked to inflammation or fibrosis stage.	22498821
Inflammation, Hemorrhage, Pancreatic Pseudocyst	Altered Intercellular Communication	The predominant histologic features were those of pancreatic pseudocyst, including a fibrotic cyst wall lacking epithelium and instead composed of myofibroblastic proliferation, hemorrhage, and inflammation.	22498822
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	T2D is primarily characterized by insulin resistance, and growing evidence has indicated the causative link between adipose tissue inflammation and the development of insulin resistance.	22499789
Inflammation	Altered Intercellular Communication	CD44 likely plays a causative role in the development of adipose tissue inflammation and insulin resistance in rodents and humans.	22499789
Plaque, Atherosclerotic	Altered Intercellular Communication	Evidence supporting a key role of Lp-PLA2-generated lysophosphatidylcholine in human atherosclerotic plaque inflammation.	22499993
Inflammation, atherosclerotic	Altered Intercellular Communication	To determine whether the level of lysophosphatidylcholine (lysoPC) generated by lipoprotein-associated phospholipase A2 (Lp-PLA2) is associated with severity of inflammation in human atherosclerotic plaques.	22499993
Inflammation	Altered Intercellular Communication	According to in vitro studies, lysoPCs are proinflammatory but the association between their generation and plaque inflammation remains unknown.	22499993
Inflammation	Altered Intercellular Communication	The associations among Lp-PLA2, lysoPCs, LPA, and proinflammatory cytokines in human plaques suggest that lysoPCs play a key role in plaque inflammation and vulnerability.	22499993
ARCN1 gene, Inflammation	Altered Intercellular Communication	Effect of incremental exercise on airway and systemic inflammation in patients with COPD.	22500008
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Airway and systemic inflammation are features of chronic obstructive pulmonary disease (COPD), and there is growing interest in clarifying the inflammatory processes.	22500008
Inflammation	Altered Intercellular Communication	A statistically significant improvement in visual acuity (p < 0.05) and a high statistically significant decrease of inflammation of the worst affected eyes (p = 0.001) were detected.	22500372
HD Term Type, Inflammation, Cachexia	Altered Intercellular Communication	Patients on HD with a BMI lower than 23 kg/m2 did not present signs of energy wasting, whereas those with a BMI higher than 23 kg/m2 had more inflammation, probably because of a greater adiposity.	22503532
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The inflammatory system is implicated in every stage of chronic kidney disease, and we hypothesized an additional value of markers of systemic inflammation in predicting response after renal artery stenting.	22503569
Hyperglycemia, Inflammation	Altered Intercellular Communication	In midlife, however, it was related to abdominal adiposity in addition to general adiposity, fasting hyperglycemia, higher HbA1c and subtle systemic inflammation.	22504289
Inflammation, Neoplasms	Altered Intercellular Communication	Several evidences have been published linking polymorphism in genes involved in chronic or recurrent inflammation with increased tumor risk and progression.	22504414
Inflammation	Altered Intercellular Communication	Moreover, caution is particularly important in patients with preoperative evidence of inflammation.	22504895
Degenerative polyarthritis, Inflammation, Calcinosis	Altered Intercellular Communication	In OA, mitochondrial-associated signaling has been implicated in the molecular events leading to cartilage degradation, including oxidative stress, defective chondrocyte biosynthesis and growth responses, increased cytokine-induced chondrocyte inflammation and matrix catabolism, cartilage matrix calcification and increased chondrocyte apoptosis.	22504941
Trachoma	Altered Intercellular Communication	The unadjusted prevalence of trachoma inflammation-follicular (TF) in children aged 1-9 years was 70.5% (95% CI: 68.6-72.3).	22506082
Inflammation, Hypertrophy	Altered Intercellular Communication	Inflammation has been proposed to be an important causative factor in ligamentum flavum hypertrophy.	22506718
Inflammation, Dental Plaque	Altered Intercellular Communication	Plaque and gingival inflammation were highly correlated with this condition, while demographic characteristics and drug dosage did not relate significantly.	22506838
Alcohol abuse	Altered Intercellular Communication	Chronic alcohol abuse and dependence are associated with dysfunctional dopaminergic neurotransmission in mesocorticolimbic circuits.	22506971
Crohn Disease	Altered Intercellular Communication	Metastatic Crohn's disease is a rare and complex inflammatory condition distinguished by cutaneous granulomatous lesions outside the gastrointestinal tract.	22507210
Inflammation, Rupture	Altered Intercellular Communication	Fourteen novel markers quantifying cardiomyocyte damage, inflammation and/or plaque rupture, and neurohormonal activation were measured at presentation.	22507551
Steatohepatitis, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Liver needle biopsy was performed in two of these subjects, confirming hepatic steatosis with minimal inflammation or fibrosis.	22507979
Diastolic dysfunction, Inflammation, Critical Illness	Altered Intercellular Communication	Severe inflammation leads to cardiac diastolic dysfunction, an independent prognostic marker for the mortality of critically ill patients.	22508290
Inflammation, Obesity	Altered Intercellular Communication	In obesity, adipose tissue becomes a significant source of chemokines and inflammatory cytokines that are associated with chronic systemic low-grade inflammation and may lead to insulin resistance.	22508338
Tubular adenoma, Papilloma, Intraductal Hyperplasia, Neoplasms	Altered Intercellular Communication	Among the 172 lesions, there were 66 (38%) fibroadenomas, 31 (18%) sclerosing adenoses, 24 (14%) fibrocystic changes, 16 (9%) mastitis/inflammations, 9 (5.5%) intraductal papillomas, 8 (5%) focal fibroses, 4 (2.5%) atypical ductal hyperplasias, 4 (2.5%) fat necroses, 2 (1%) phyllodes tumors, 1 (0.5%) tubular adenomas, 1 (0.5%) epidermal inclusion cysts, and 6 (3.5%) "other benign lesions."	22508447
Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	The presence of extracellular and intracellular crystalline iron in the airway lumen and/or mucosa with associated varying degrees of ulceration and inflammation confirms the diagnosis.	22508539
Inflammation	Altered Intercellular Communication	Filarial lymphatic pathology is of multifactorial origin, with inflammation, lymphangiogenesis, and innate immune responses all playing important roles.	22508858
Inflammation, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Chronic inflammation is now thought to play a key pathogenetic role in the associations of obesity with insulin resistance and diabetes.	22509446
Inflammation, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Based on our recent findings on persistent organic pollutants (POPs) including the lack of an association between obesity and either insulin resistance or diabetes prevalence among subjects with very low concentrations of POPs, we hypothesized that POP concentrations may be associated with inflammation and modify the associations between inflammation and insulin resistance in non-diabetic subjects.	22509446
Inflammation, Eye pain	Altered Intercellular Communication	[Phase III open-label study of nepafenac ophthalmic suspension 0.1% for inflammation and ocular pain following ophthalmic surgery].	22509696
Cataract, Eye pain, Acute inflammation	Altered Intercellular Communication	To examine the efficacy and safety of nepafenac ophthalmic suspension 0.1% on postoperative inflammation and eye pain with intraocular surgery, other than cataract surgery.	22509696
Cataract, Eye pain, Acute inflammation	Altered Intercellular Communication	Nepafenac ophthalmic suspension 0.1% is considered safe and efficious not only following cataract surgery but also for postoperative inflammation and eye pain in intraocular surgery.	22509696
Carcinoma of lung, Pneumonia, Interstitial, Pulmonary Emphysema	Altered Intercellular Communication	We therefore investigated associations between SFTPD variations and lung cancer as well as emphysema and interstitial pneumonia, which are characterized by chronic inflammation from which lung cancer often arises.	22509983
Fibrosis Assessment, Dacryoadenitis	Altered Intercellular Communication	Here are 23 lesions of idiopathic lacrimal gland inflammation collected retrospectively, whose histopathologic types were classified based on different characteristics, while the fibrosis degrees were measured.	22510006
Inflammation	Altered Intercellular Communication	Blinded histologic evaluation revealed a trend toward normal elastic fiber appearance (P = 0.255), increased wound complications (P = 0.546), and mild inflammation (P = 0.462) in the surgical group.	22510895
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Our findings support the conclusion that adipokines involved in inflammation are associated with colorectal cancer risk, but that their effects may be mediated mostly by insulin, with leptin exerting an independent effect.	22511581
Anorexia Nervosa, Congenital Abnormality	Altered Intercellular Communication	Structural brain abnormalities in adolescent anorexia nervosa before and after weight recovery and associated hormonal changes.	22511729
Parotitis, Inflammation	Altered Intercellular Communication	Recurrent parotitis is an acute, severe inflammation of one or both parotid glands, the major salivary glands in young children.	22512231
Arterial Stiffness, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The effect of sitagliptin versus glibenclamide on arterial stiffness, blood pressure, lipids, and inflammation in type 2 diabetes mellitus patients.	22512265
Mycobacterium Infections, Asthma, Respiratory Hypersensitivity, Inflammation	Altered Intercellular Communication	BCG and other mycobacterial infections suppress airway hyper-responsiveness and inflammation in asthma models; however, its efficacy in human populations remains controversial.	22512632
Communicable Diseases, Chlamydia, Inflammation, Chronic disease of respiratory system	Altered Intercellular Communication	The current study sought to determine if infection with Chlamydia triggers the production of pathogen-specific IgE in children with chronic respiratory diseases which might contribute to inflammation and pathology.	22512977
Reactive airway disease, Chlamydia, allergic inflammation, Asthma	Altered Intercellular Communication	IgE antibodies play a central role in allergic inflammation; therefore production of Chlamydia-specific IgE may prove significant in the exacerbation of chronic, allergic airway diseases, thus highlighting a direct role for Chlamydia in asthma pathogenesis.	22512977
Inflammation, Squamous cell carcinoma	Altered Intercellular Communication	In other centers, she had undergone previous biopsies, the results of which were suggestive of squamous cell carcinoma and aspecific inflammation.	22513067
Inflammation	Altered Intercellular Communication	Transforming growth factor-beta1 (TGF-beta1) is a pleiotropic cytokine that plays important roles in immunity and inflammation.	22513132
Autoimmune Diseases, glycation, Inflammation	Altered Intercellular Communication	Interaction of advanced glycation end products (AGEs) with their receptors (RAGE) plays an important role in inflammation in auto-immune diseases.	22513366
Inflammation, Virus Diseases	Altered Intercellular Communication	Neutralization of Pellino-1 may therefore provide opportunities to inhibit potentially harmful neutrophilic inflammation of the airways induced by respiratory viruses, without loss of control of the underlying viral infection.	22514342
Chronic lymphocytic inflammation, Alopecia, CTCAE, Scleroderma	Altered Intercellular Communication	To our knowledge, this is the first report of alopecia with perineural lymphocytic inflammation as a presenting sign of linear scleroderma en coup de sabre.	22515223
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation and cancer: chemical approaches to mechanisms, imaging, and treatment.	22515568
Inflammation, Primary malignant neoplasm, Multiple Chronic Conditions, Cardiovascular Diseases	Altered Intercellular Communication	Chronic inflammation contributes to the etiology of multiple diseases, especially those associated with aging, such as cancer and cardiovascular disease.	22515568
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The current perspective summarizes our research on unsaturated fatty acid oxidation in the context of inflammation and cancer.	22515568
Alopecia Areata, Alopecia	Altered Intercellular Communication	Alopecia areata (AA) is a chronic inflammatory condition characterized by hair loss, most frequently from the scalp.	22515582
Vasculitis, Leukocytoclastic, Cutaneous, Inflammation	Altered Intercellular Communication	Cutaneous leukocytoclastic vasculitis (CLV) is a necrotizing inflammation of the small vessels in the dermis.	22515974
Inflammation, Coronary artery	Altered Intercellular Communication	The noninvasive assessment of coronary artery plaque biology would be a major advance particularly in the identification of vulnerable plaques, which are associated with specific pathological characteristics, including micro-calcification and inflammation.	22516444
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	(An Observational PET/CT Study Examining the Role of Active Valvular Calcification and Inflammation in Patients With Aortic Stenosis; NCT01358513).	22516444
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We will review the relative strengths and limitations of MRE as applied to clinical evaluation and therapeutic decisions, including the use of the unique capacity to delineate active inflammation and fibrosis in the submucosal and deeper enteric tissues, which is beyond the diagnostic reach of endoscopy and biopsy.	22517074
Intraocular inflammation, PDR gene, Retinal Diseases	Altered Intercellular Communication	Intraocular inflammation seems to be involved in PDR but does not seem to be prominent in early retinopathy stages, i.e.	22520269
Gastroesophageal reflux disease, Inflammation, Helicobacter pylori	Altered Intercellular Communication	Although gastroesophageal reflux disease and Helicobacter pylori are both associated with chronic inflammation of the adjacent cardia mucosa, it is not known whether these lead to derangements of the desmosomal complexes.	22521077
Inflammation	Altered Intercellular Communication	Nasal irrigations are often mentioned as measures for treating sinonasal inflammations.	22521235
Inflammation, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	Obstructive sleep apnea (OSA) has been associated with chronic inflammation.	22521311
Steatohepatitis, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Inflammation	Altered Intercellular Communication	Visceral adiposity is associated with hepatic steatosis, inflammation, and fibrosis in non-alcoholic fatty liver disease (NAFLD).	22521350
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	VAI was not associated with steatosis, lobular inflammation or fibrosis, but WC was associated with fibrosis (p=0.01).	22521350
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Fatty degeneration	Altered Intercellular Communication	In NAFLD, VAI is not associated with steatosis, inflammation or fibrosis.	22521350
Endocrine System Diseases, Traumatic injury	Altered Intercellular Communication	It may also result from injurious processes including frostbite, physical trauma, inflammatory conditions, and various endocrinopathies.	22522358
REM Sleep Behavior Disorder, palladium, RNA Recognition Motif, Parkinson Disease	Altered Intercellular Communication	Rapid eye movement sleep behavior disorder (RBD) is common in Parkinson disease (PD), but its relationship to the varied neurotransmitter deficits of PD and prognostic significance remain incompletely understood.	22522445
Inflammation	Altered Intercellular Communication	Combined significant (2+ or 3+) acute and chronic inflammation had a specificity of 98% and a negative predictive value of 97%.	22523211
Hematoxylin and eosin stain method, Inflammation	Altered Intercellular Communication	Our results show that, in our institution, HP can be seen relatively easily with H&E staining in the majority of cases; however, a small number of cases with significant inflammation can be missed if stains are not used.	22523211
Neoplasms	Altered Intercellular Communication	The interplay between p53 and p73 and HPV16 may lead to deregulation of cell cycle and apoptosis, through which inflammation/immune responses control the HPV clearance and escape of immune surveillance, and subsequently contribute to tumor HPV16 status.	22523600
Inflammation, Migraine Disorders, Atherosclerosis	Altered Intercellular Communication	There is a relationship between atherosclerosis and inflammation in migraine patients.	22524899
Inflammation, Hypertension, CTCAE, Obesity	Altered Intercellular Communication	Obesity and hypertension are associated with an adverse metabolic profile and systemic low-grade inflammation.	22525206
Lymphoid hyperplasia, Thyroid associated opthalmopathies, Parasitic Diseases, Eosinophilic granulomatosis with polyangiitis, Ocular Adnexal Lymphoma, Blepharitis, Granulomatosis with polyangiitis, Orbital Pseudotumor, "Sjogrens Syndrome	Altered Intercellular Communication	The differential diagnosis extends to thyroid eye disease; blepharitis; Sjogren's syndrome; Churg-Strauss vasculitis; Wegener's granulomatosis; Gleich syndrome; orbital and ocular lymphoid hyperplasia or adnexal lymphoma; idiopathic orbital inflammatory disease/idiopathic sclerosing orbital inflammation; rarely, orbital parasitosis; and IgG4-related diseases.	22525399
Inflammation, Pre-Eclampsia	Altered Intercellular Communication	Preeclampsia may be due to an excess of circulating anti-angiogenic growth factors derived from the placenta, but metabolic syndrome-like disorders may also set off a cascade of placental and systemic inflammation and oxidative stress.	22525475
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The differences between groups were compared by calculating the ratio of inflammation above G2 or fibrosis staging above S2.	22525497
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The percentages of the chronic HBV carriers with liver histopathology inflammation graded above G2 or fibrosis staging above S2 were 26.5% (36/136) in 11 to 29 year-old group, 39.4% (37/94) in 30-39 year-old group and 58.1% (36/62) in 40-60 year-old group.	22525497
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	39.4% (37/94) of chronic HBV carriers were found with inflammation graded above G2 or fibrosis staging above S2 in 30-39 year-old group, no statistically significant difference found between group 30-39 years old and group and 40-60 years old 58.1% (36/62) (P less than 0.01).	22525497
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	26.5% (36/136) of chronic HBV carriers under 30 years old were with inflammation graded above G2 or fibrosis staging above S2 as compared with the percentage of 46.8% (73/156) in the chronic HBV carriers over 30 years old group, and significant difference existed between the two groups (P less than 0.01).	22525497
Malignant tumor of extrahepatic bile duct, Inflammation	Altered Intercellular Communication	The significance of the presence of preoperative inflammation for the prognosis of patients with extrahepatic bile duct cancer (BDCA) was evaluated.	22526039
Inflammation, In-Stent Restenosis Indicator	Altered Intercellular Communication	Chronic continuous inflammation plays an important role after implantation of both types of stent with regard to in-stent restenosis in patients on hemodialysis.	22526379
Inflammation, Fracture	Altered Intercellular Communication	Low-grade inflammation, assessed by serum high-sensitivity C-reactive protein (hsCRP) concentration, is associated with higher fracture risk irrespective of areal bone mineral density (aBMD).	22527204
Noncommunicable Diseases, Inflammatory abnormality of the eye	Altered Intercellular Communication	Forty ocular samples from non-infectious patients without ocular inflammation were collected as controls.	22527320
Inflammation	Altered Intercellular Communication	However gut flora changes, inflammation and neuro-glial injury have been implicated.	22527995
helium, Inflammation	Altered Intercellular Communication	The correlation network showed Prevotella to be linked to improved cognition and decreased inflammation in patients without HE recurrence.	22527995
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	Relative contributions of inflammation and inadequate protein intake to hypoalbuminemia in patients on maintenance hemodialysis.	22528583
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	We hypothesize that these inadequate protein intake and inflammation contribute somewhat equally to hypoalbuminemia.	22528583
Idiopathic Inflammatory Myopathies, Atrophic, Myositis	Altered Intercellular Communication	Use of this strategy may prove useful in the study of idiopathic inflammatory myopathy and other diseases characterized by both muscle inflammation and atrophy.	22528929
Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Inflammation and adaptive immunity modulate atherosclerosis and plaque instability.	22529217
Inflammation, mitral annulus calcification	Altered Intercellular Communication	Association of mitral annulus calcification with high-sensitivity C-reactive protein, which is a marker of inflammation.	22529527
Inflammation, Premature calcification of mitral annulus, MARCKS wt Allele	Altered Intercellular Communication	There are limited clinical data revealing the relationship between mitral annular calcification (MAC) and systemic inflammation.	22529527
Inflammation, MARCKS wt Allele	Altered Intercellular Communication	Our study demonstrated that hs-CRP, which is a sensitive marker of systemic inflammation, increased in patients with MAC.	22529527
Inflammation, Hematuria, CTCAE	Altered Intercellular Communication	Inflammation, hematuria and smoking did not confound the results.	22530010
Inflammation	Altered Intercellular Communication	One important finding is that survivin was not influenced by confounders like inflammation and exhibited a relatively low number of false-positives.	22530010
Inflammation, Crohn Disease	Altered Intercellular Communication	This aspect was not suggestive of an active inflammation such as Crohn's disease, where a marked contrast medium enhancement should be expected.	22530462
Inflammation, Liver diseases, Chronic liver disease, Lymphoproliferative Disorder of the Skin	Altered Intercellular Communication	Based on the essential pathogenic role of inflammation for progression of liver diseases, we hypothesized that sIL-2R might be an indicator of inflammatory cell activation and disease severity in patients with chronic liver diseases (CLD).	22530792
Inflammation, Kidney Failure, Liver Dysfunction	Altered Intercellular Communication	In addition, renal failure was an important confounder of sIL-2R levels independent of liver dysfunction and inflammation.	22530792
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Hypocortisolism may contribute to increased risk of depressive symptoms as a result of the loss of glucocorticoid attenuation of stress-induced inflammation.	22531368
Inflammation, Hyperintensity of cerebral white matter on MRI	Altered Intercellular Communication	White matter hyperintensities, systemic inflammation, brain growth, and cognitive functions in children exposed to air pollution.	22531421
Inflammation, Cognition Disorders, Nerve Degeneration	Altered Intercellular Communication	Identification of biomarkers associating systemic inflammation to brain growth is critical for detecting children at higher risk for cognitive deficits and neurodegeneration, thereby warranting early implementation of neuroprotective measures.	22531421
Inflammation	Altered Intercellular Communication	The regulated upon activation, normal T cell expressed and secreted (RANTES) production in psoriatic lesions may amplify the inflammation in these lesions.	22531960
Nasal inflammation, Congestion	Altered Intercellular Communication	Therefore, especially in the management of AR-related nasal inflammation and congestion, nGCSs are considered the most appropriate treatment.	22532282
allergic inflammation	Altered Intercellular Communication	This review will discuss the pathophysiology of allergic inflammation in the nasal mucosa and the mechanism of action of nGCSs; also the efficacy and safety of nGCSs will be discussed by focusing on clinical evidence.	22532282
Gingival Hyperplasia, Inflammation	Altered Intercellular Communication	Gingival enlargement and inflammation had completely disappeared after nonsurgical treatment for the maxilla and after surgical treatment for the mandible.	22532949
Inflammation	Altered Intercellular Communication	HIV status, burden of comorbid disease, and biomarkers of inflammation, altered coagulation, and monocyte activation.	22534147
Inflammation, HIV, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Biomarkers of inflammation, altered coagulation, and monocyte activation are associated with mortality and cardiovascular disease (CVD) in the general population and among human immunodeficiency virus (HIV)-infected people.	22534147
Inflammation	Altered Intercellular Communication	These data suggest that ongoing HIV replication and immune depletion significantly contribute to increased prevalence of elevated biomarkers of inflammation, altered coagulation, and monocyte activation.	22534147
Inflammation	Altered Intercellular Communication	A link between androgen deficiency and fibrinolysis, protein synthesis deficiency, inflammation and trophicity is well documented in the literature.	22534310
Crohn Disease, Inflammation, Inflammatory disorder	Altered Intercellular Communication	Crohn's disease is a chronic transmural inflammatory disorder characterized by inflammation of the intestine.	22534313
Inflammation, Diabetes Mellitus, Insulin-Dependent	Altered Intercellular Communication	Urine a-Glutathione S-transferase, systemic inflammation and arterial function in juvenile type 1 diabetes.	22534514
Diabetes Mellitus, Insulin-Dependent, Inflammation, Vascular Diseases	Altered Intercellular Communication	To investigate in young patients with type 1 diabetes whether urine a-Glutathione S-transferase to creatinine ratio (a-GST:crea) relates to markers of systemic inflammation and subclinical vasculopathy.	22534514
Inflammation, Acute mediastinitis	Altered Intercellular Communication	Monitoring of biochemical markers of inflammation in acute mediastinitis (AM) can be useful in the modification of treatment.	22534711
Inflammation	Altered Intercellular Communication	The combination of the two processes can exacerbate inflammation, resulting in increases in both resistance to erythropoietin (EPO) and mortality.	22535158
Neurogenic Inflammation	Altered Intercellular Communication	These symptoms may be the cause of a phenomenon described in the literature as a neurogenic skin inflammation.	22535604
Inflammation, Hemochromatosis, Fatty Liver, Hyperferritinaemia, Malignant Neoplasms, HEMOCHROMATOSIS, TYPE 4, Juvenile-Onset Still Disease, Liver Cirrhosis	Altered Intercellular Communication	Even when inflammation, cirrhosis, Still's disease, fatty liver and malignancy are excluded, there remains a group of patients with unexplained hyperferritinaemia for whom rare forms of haemochromatosis (ferroportin disease) are a consideration.	22535864
Inflammation, Malnutrition	Altered Intercellular Communication	Malnutrition and chronic inflammation in dialysis patients negatively impacts prognosis.	22536073
Amyotrophic Lateral Sclerosis, Inflammation, Trauma, Nervous System	Altered Intercellular Communication	While free radicals and inflammation constitute major routes of neuronal injury occurring in amyotrophic lateral sclerosis (ALS), neither antioxidants nor non-steroidal anti-inflammatory drugs have shown significant efficacy in human clinical trials.	22537108
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	We examined the possibility that concurrent blockade of free radicals and prostaglandin E(2) (PGE(2))-mediated inflammation might constitute a safe and effective therapeutic approach to ALS.	22537108
Inflammation	Altered Intercellular Communication	Plasma CD40L, CXCL5, CCL5 and EGF are mainly platelet-derived, suggesting a role of platelets in immune responses and inflammation.	22537155
Acute Coronary Syndrome, Periodontitis, Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	An association exists between chronic infection-induced inflammation, such as periodontitis, and acute coronary syndrome (ACS).	22537345
Nonalcoholic Steatohepatitis, Inflammation, Hepatitis C	Altered Intercellular Communication	Circulating microparticles as disease-specific biomarkers of severity of inflammation in patients with hepatitis C or nonalcoholic steatohepatitis.	22537612
Carcinogenic Chlorinated Hydrocarbon, Inflammation, Hepatitis C, Chronic	Altered Intercellular Communication	Microparticles released into the bloodstream upon activation or apoptosis of CD4(+) and CD8(+) T cells correlate with inflammation as determined by histologic analysis in patients with chronic hepatitis C (CHC).	22537612
Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Inflammation, Fatty Liver Disease	Altered Intercellular Communication	We compared profiles of circulating microparticles from patients with NAFL and NASH (n = 67) to those of CHC (n = 42), with healthy individuals (controls) using flow cytometry; the profiles were correlated with inflammation grade and fibrosis stage based on histologic analyses.	22537612
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We assessed the ability of the profiles to determine the severity of inflammation and fibrosis based on serologic and histologic analyses.	22537612
Chronic liver disease, Hepatic inflammation	Altered Intercellular Communication	Quantification of immune cell microparticles from serum samples can be used to assess the extent and characteristics of hepatic inflammation in patients with chronic liver disease.	22537612
Refractory anemias, Inflammation	Altered Intercellular Communication	In immunohistochemistry, inflammation induced by RA/CyD was more moderate than that induced by RA.	22538278
Fibrous, Inflammation	Altered Intercellular Communication	Some of the extracted adherent tissue consisted of hyalinized fibrous tissue that had the appearance of soft tissue which had organized because of inflammation.	22538287
Inflammation, Mucous Membrane	Altered Intercellular Communication	To evaluate developmental changes in mucosal inflammatory response, we used trinitrobenzene sulfonic acid (TNBS)-induced inflammation as a nonspecific insult and compared mucosal injury in newborn vs. adult mice.	22538401
Inflammation, Thrombosis	Altered Intercellular Communication	Deficiencies in the protein C (PC) pathway components not only promote thrombosis, but also exacerbate inflammation.	22538795
Inflammation, Lymphoma	Altered Intercellular Communication	The expressions of miR-21, miR-155 and miR-210 were assayed by RT-PCR in plasma of 54 cases of lymphoma, 10 cases of lymphonode inflammation and 27 cases of normal controls.	22541087
Inflammation, Lymphoma	Altered Intercellular Communication	The results indicated that the expressions of miR-21, miR-155 and miR-210 in plasma of lymphoma patients were higher than those of control group and lymphonode inflammation group (P < 0.05).	22541087
Inflammation, Gastritis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	This study showed that CagA-positive H. pylori infection is associated with more severe gastritis and with increased bacterial density and inflammation in the biopsy specimens.	22541262
Inflammatory Bowel Diseases, Dysbiosis, Obesity, Hypersensitivity, Disease	Altered Intercellular Communication	Deviations from healthy microbial compositions (dysbiosis) have been linked with important human diseases, including inflammation-linked disorders, such as allergies, obesity, and inflammatory bowel disease.	22541361
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histologic evidence of inflammation as well as degree of subepithelial fibrosis at presentation was compared with most recent biopsies while receiving PPI therapy.	22541409
Inflammation, "Extra-osseous Ewings sarcoma	Altered Intercellular Communication	Patients with EoE treated with PPIs show an improvement in symptoms and z-scores despite persistent eosinophilic inflammation.	22541409
Communicable Diseases, Inflammation, Traumatic injury	Altered Intercellular Communication	Patients underwent penetrating keratoplasty (PK) (n = 142, 39.2%), anterior lamellar keratoplasty (ALK) (n = 127, 35.1%), or a peripheral corneoscleral patch graft (n = 93, 25.7%) most commonly for inflammation (n = 68, 18.8%), trauma (n = 66, 18.2%), or infection (n = 66, 18.2%).	22541633
Keratitis	Altered Intercellular Communication	Active corneal inflammation (hazard ratio [HR], 2.5; 95% CI, 1.4-4.4; P = 0.003) and larger donor and recipient graft sizes of >= 9 mm (HR, 17.9; 95% CI, 2.3-140.3; P = 0.006) were risk factors for physiologic graft failure in anatomically successful eyes with central tectonic grafts.	22541633
Keratitis	Altered Intercellular Communication	For anatomically successful cases with central tectonic grafts, active corneal inflammation and donor size >= 9 mm were risk factors for physiologic failure.	22541633
Inflammation, Myocardial Ischemia	Altered Intercellular Communication	Low-level exposure to ambient particulate matter is associated with systemic inflammation in ischemic heart disease patients.	22541720
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	In most eyes with uveitis and ERM, VA remains stable if ocular inflammation and comorbidities are addressed appropriately.	22541930
Tissue Factor-Derived Microparticle, Inflammation	Altered Intercellular Communication	Although there was a statistically significant decrease in TFMP, this decrease did not correlate with changes in markers of thrombin generation or inflammation.	22542362
Inflammation	Altered Intercellular Communication	In cardiac rehabilitation patients, particles were associated with subclinical decreases in parasympathetic modulation, prolongation of late repolarization duration, increased blood pressure, and systemic inflammation.	22542955
Associate of Engineering, Epiglottitis, Inflammation, Airway Obstruction	Altered Intercellular Communication	Acute epiglottitis (AE) is inflammation of the epiglottis and contiguous tissues, which carries a potential for complete airway obstruction.	22543595
Hepatitis, Hyperglycemia, Hypertriglyceridemia, Fatty degeneration, Obesity, Fibrosis, Liver	Altered Intercellular Communication	Obesity, hypertriglyceridemia, hyperglycemia, liver fibrosis, and liver inflammation were all independently associated with worse steatosis.	22543885
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Degrees of HS, iron deposition, inflammation, and fibrosis were analyzed in liver resection (n = 37) and biopsy (n = 19) specimens.	22543969
Inflammation	Altered Intercellular Communication	Nematode-induced low-grade chronic inflammation of the iris.	22543998
Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	The reported associations between metabolic syndrome (MetS) and systemic vascular inflammation/insulin resistance prompted the author to determine the predictive ability of markers for MetS in the occupational field.	22544164
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Many of these genes are involved in inflammation regulation and neurodegeneration, e.g.	22545106
Inflammation	Altered Intercellular Communication	Over-expression of genes associated with inflammation (CD86, CD209, CLEC4, EGFR2, TFF3, among others) was observed in the CSP group.	22545113
Inflammation	Altered Intercellular Communication	When the analysis was restricted to ECD kidneys, genes involved in inflammation were also differentially up-regulated in ECD kidneys undergoing CSP.	22545113
TNF protein, human, Chagas Cardiomyopathy, Myocarditis	Altered Intercellular Communication	These results indicate that reduced production of the cytokines IL-10 and IL-17 in association with high levels of IFN-g and TNF-a is correlated with the severity of the Chagas' disease cardiomyopathy, and the immunological imbalance observed may be causally related with deficient suppressor activity of regulatory T cells that controls myocardial inflammation.	22545173
Inflammation	Altered Intercellular Communication	Punch biopsy of the skin lesion showed ulceration and dense dermal acute and chronic inflammation.	22545328
Inflammation, Traumatic injury	Altered Intercellular Communication	The patient denied any history of trauma, rubbing, insect bite, or inflammation at the site.	22545327
Inflammation, Necrosis	Altered Intercellular Communication	The first biopsies were inconclusive, showing only necrotic cells and purulent inflammation with epithelial elements.	22545391
Inflammation, Myocardial Infarction	Altered Intercellular Communication	[The reactants of acute phase of inflammation and anti-inflammatory cytokines under various complications of cardiac infarction].	22545471
Inflammation	Altered Intercellular Communication	This is potentially associated with bacterial translocation from the gut leading to local and systemic inflammation.	22545716
Bacteremia, Inflammation, Endotoxemia, Peritonitis	Altered Intercellular Communication	Open appendectomy, in case of peritonitis, increased the incidence of bacteremia, endotoxemia, and systemic inflammation compared with laparoscopic appendectomy.	22546132
Sepsis, Inflammation	Altered Intercellular Communication	Early enhanced postoperative systemic inflammation may cause lower transient immunologic defense after laparotomy (decrease of HLA-DR), leading to enhanced sepsis in these patients.	22546132
Inflammation, "Alzheimers Disease", Periodontal Diseases, Data types - Address	Altered Intercellular Communication	Chronic inflammation in periodontal disease has been suggested as a potential risk factor in Alzheimer's disease (AD).	22546352
Inflammation, Chronic Obstructive Airway Disease, Premature aging syndrome	Altered Intercellular Communication	Chronic obstructive pulmonary disease/emphysema (COPD/emphysema) is characterized by chronic inflammation and premature lung aging.	22546858
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	Inhibition of lung inflammation by an NF-kB/IKK2 inhibitor did not have any beneficial effect on emphysema.	22546858
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Thus, SIRT1 protects against emphysema through FOXO3-mediated reduction of cellular senescence, independently of inflammation.	22546858
Inflammation	Altered Intercellular Communication	Both acute and chronic blood glucose variability can induce oxidative stress and chronic inflammation.	22547264
Tumor necrosis, precancerous lesions, Pneumonitis	Altered Intercellular Communication	Some inflammatory factors, such as tumor necrosis factor, interleukin 1 and interleukin 6, were upregulated in lung tissue of transgenic mice compared with that of wild-type mice, implying that long-term HER2 overexpression could induce serious lung inflammation and some precancerous lesions.	22547270
Inflammation, Carcinogenesis	Altered Intercellular Communication	This model would be useful for studying the mechanism of HER2 involvement in lung carcinogenesis and for understanding the relationship between carcinogenesis and inflammation.	22547270
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Chronic low-grade inflammation is crucial for the development of insulin resistance and type 2 diabetes mellitus (T2DM), and immunocompetent cells, such as T-cells, B-cells, mast cells and macrophages, regulate the pathogenesis of T2DM.	22547395
Inflammation	Altered Intercellular Communication	Our data indicated that a higher frequency of activated NK cells may participate in the obesity-related chronic inflammation involved in the pathogenesis of T2DM.	22547395
Refractory anemias, Inflammation	Altered Intercellular Communication	However, whether Cyr61 in turn regulates Th17 cell differentiation and further enhances inflammation of RA remained unknown.	22547695
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	Radiation alone induced acute pulmonary inflammation and lung fibrosis after 16 weeks associated with reduced life span.	22547771
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	VCT, MRI, and histology showed that LY2109761 markedly reduced inflammation and pulmonary fibrosis resulting in prolonged survival.	22547771
Inflammation	Altered Intercellular Communication	The markers of inflammation secreted by the adipose tissue (adiponectin, leptin, resistin) showed significant differences in patients from the case group (with PAOD) compared to the control group.	22547903
Inflammation, Glucocorticoid deficiency with achalasia, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Inflammation plays a key role in the pathophysiology of abdominal aortic aneurysms (AAAs).	22547907
Inflammation, palladium, Communicable Diseases, Obesity, Dental Plaque	Altered Intercellular Communication	Plaque index, reflecting dental plaque, and PD, closely linked with periodontal inflammation and infection, are statistically associated with high BMI and obesity, independently of dietary patterns and insulin resistance.	22548413
Refractory anemias, Inflammation	Altered Intercellular Communication	We have previously reported that high levels of antibodies specific for native human type II collagen (anti-CII) at the time of RA diagnosis were associated with concurrent but not later signs of inflammation.	22548748
Refractory anemias, Inflammation	Altered Intercellular Communication	In contrast, anti-cyclic citrullinated peptide antibodies (anti-CCP) were associated both with late inflammation and late radiological destruction in the same RA cohort.	22548748
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Plasma asymmetric dimethylarginine in active rheumatoid arthritis: links with oxidative stress and inflammation.	22549098
Inflammation, Neck stiffness, Globus Sensation, Neck Pain	Altered Intercellular Communication	Prevertebral tendinitis should be considered when patients suffer from neck pain, neck stiffness, and globus sensations despite low signs of inflammation in the laboratory report.	22549265
Inflammation, Hemorrhage, Obesity, Abdominal, Fibrosis Assessment	Altered Intercellular Communication	Conversion to laparotomy was required for seven patients (35 %) due to bleeding (n = 1), Roux loop venous congestion (n = 1), abdominal obesity (n = 2), and severe fibrosis and inflammation around the cyst (n = 3).	22549376
Inflammation, Neoplasms, Diverticular Diseases	Altered Intercellular Communication	Bowel cleansing, polyps, angioectasias, diverticular disease, inflammation, and neoplasm were also verified.	22549378
Late Onset Disorders, Inflammation, Protein Glycosylation	Altered Intercellular Communication	Glycosylation aberrancy was comparable in patients with and those without antinuclear antibodies and in both early- and late-onset disease and exhibited at most a weak correlation with markers of inflammation.	22549726
Gingivitis, Periodontal Diseases, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Patients with ACS had more severe periodontal disease and higher levels of gingival inflammation than the control group (p < 0.001).	22550814
Inflammation, Periodontal Ligament	Altered Intercellular Communication	Appearance of antibodies to HSP plays a role in immune reactions, which maintain chronic inflammation of periodontium.	22550879
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Subclinical inflammation and atrial stretch have been recognized as important contributors to atrial fibrillation (AF) onset and perpetuation.	22552174
Inflammation, Drowning, Lung Injury, Hypothermia due to exposure	Altered Intercellular Communication	These observations suggest characteristic molecular biological patterns of pulmonary injury involving suppression of pulmonary surfactants and activation of early-phase mediators of inflammation in drowning, with high mRNA expression levels of pulmonary surfactants in fatal hypothermia; however, there was no significant difference among these markers in immunohistochemical detection, except for SP-A.	22552475
Inflammation, Cholestasis	Altered Intercellular Communication	In histological findings, bile duct proliferation and cholestasis predominated in the low group and portal inflammation predominated in the high group.	22552497
Inflammation, Exacerbation	Altered Intercellular Communication	[Etiology and biomarkers of systemic inflammation in mild to moderate COPD exacerbations].	22552550
Inflammation, Exacerbation, Symptom aggravating factors	Altered Intercellular Communication	Compared to viral exacerbations, bacterial aggravations were associated with a systemic inflammation of higher magnitude.	22552550
Inflammation, Exacerbation	Altered Intercellular Communication	Biomarkers of systemic inflammation increase during mild to moderate COPD exacerbations.	22552550
Inflammation, Bacterial Infections, Exacerbation	Altered Intercellular Communication	The increase in systemic inflammation seems to be limited to exacerbations caused by bacterial infections.	22552550
Granulomatous inflammation	Altered Intercellular Communication	MALDI-IMS localized signals consistent with ESAT-6 only within sites of granulomatous inflammation, whereas P. acnes signals were distributed throughout the specimen.	22552860
Communicable Diseases, Inflammation	Altered Intercellular Communication	In the two investigated patients, there was no evidence of chronic HHV6 infection, minimal evidence of cerebral inflammation, and no significant improvement with pulse with intravenous methylprednisolone and immunoglobulin.	22554258
Inflammation, Disease	Altered Intercellular Communication	Low-grade inflammation in early childhood might protect from allergic diseases later in life.	22554299
Inflammation	Altered Intercellular Communication	However, our results suggest that the role played by the environmental factors in low-grade inflammation may differ between sensitized and non-sensitized children.	22554299
Inflammation, Fibrosis Assessment, Connective Tissue Diseases, Peyronie Disease	Altered Intercellular Communication	Peyronie 's disease is an acquired connective tissue disorder of the penile tunica albuginea with fibrosis and inflammation.	22555030
Inflammation, Demographics Domain, Coronary heart disease, Diabetes Mellitus, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Angiogenesis plays a role in the pathogenesis of coronary heart disease (CHD) and diabetes mellitus (DM) pathology, and certain angiogenic factors are increased by inflammation.	22555486
Inflammation, Demographics Domain, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Sixty-six hemodialysis patients were enrolled in the study, of whom 22 (33.3%) suffered from CHD , 22 (33.3%) from DM, and 28 (42.4%) from inflammation.	22555486
Inflammation, Demographics Domain, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	These markers were compared between hemodialysis patients with and without CHD, DM, and inflammation.	22555486
Inflammation, Demographics Domain, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Neither angiogenin nor VEGFA levels differed significantly between hemodialysis patients with and without CHD, DM, or inflammation.	22555486
Inflammation, Demographics Domain, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Plasma angiogenin and VEGFA levels are markedly increased in hemodialysis patients, but not associated with CHD, DM, or inflammation among hemodialysis patients.	22555486
Inflammation, Snowflake vitreoretinal degeneration, Aphakia, Diabetes Mellitus, Myopia, Pseudophakia, Senility	Altered Intercellular Communication	Several elements can be responsible for vitreous modifications, such as senility, myopia, aphakia, pseudophakia, diabetes, degeneration vitreous retinal hereditary, traumatisms, inflammation.	22555828
Acoustic Neuroma, Hemorrhage, Inflammation	Altered Intercellular Communication	Biological processes like intratumoral hemorrhage, cell proliferation, microvessel density, and inflammation were analyzed in order to determine their role in vestibular schwannoma development.	22555941
Inflammation, Neoplasms	Altered Intercellular Communication	Intratumoral hemosiderin, microvessel density, and inflammation were significantly positively correlated with tumor size and the tumor growth index.	22555941
Inflammation, Endothelial dysfunction, Metabolic Syndrome X	Altered Intercellular Communication	Connection between telomerase activity in PBMC and markers of inflammation and endothelial dysfunction in patients with metabolic syndrome.	22558213
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The present study tried to investigate the implications of telomerase activity with inflammation and impaired endothelial function in patients with metabolic syndrome.	22558213
Inflammation, Endothelial dysfunction, Diabetes Mellitus	Altered Intercellular Communication	In conclusion, in patients with MS characterised by a strong dyslipidemic profile and low diabetes prevalence, significant telomerase activity was detected in circulating PBMC, along with elevated markers of inflammation and endothelial dysfunction.	22558213
Metabolic Diseases, Metabolic Syndrome X, MS gene, Cardiovascular Diseases	Altered Intercellular Communication	Metabolic syndrome (MS) is a constellation of metabolic derangements associated with vascular endothelial dysfunction and oxidative stress and is widely regarded as an inflammatory condition, accompanied by an increased risk for cardiovascular disease.	22558213
Inflammation, Mass Behavior	Altered Intercellular Communication	PEA acts as an endogenous agent with an autacoid local inflammation antagonism and modulates mast cell behavior controlling both acute and chronic inflammation.	22558609
Inflammation, Ichthyosis Bullosa of Siemens, Irritable Bowel Syndrome	Altered Intercellular Communication	Recent studies suggest that irritable bowel syndrome (IBS) is associated with low-grade inflammation.	22558797
Inflammation, Bacterial Infections	Altered Intercellular Communication	Autoimmune triggering of inflammation and bacterial infection is hypothesized to be involved in the pathogenesis.	22560016
Inflammation, Dermatitis, Atopic	Altered Intercellular Communication	Topical corticosteroids are used to treat inflammation and relieve itching in atopic dermatitis, but their use is limited by adverse reactions.	22560125
Sexual Dysfunction	Altered Intercellular Communication	The relationship between the older antiepileptic drugs (AEDs) and sexual dysfunction has long been known and it is likely to be related to sexual hormonal changes.	22560189
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Patients with inflammatory bowel disease exhibited a very high risk of transfusion-induced red cell alloimmunization, possibly potentiated by inflammation.	22560809
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation and coagulation markers and kidney function decline: the Multi-Ethnic Study of Atherosclerosis (MESA).	22560844
Inflammation, Kidney Diseases	Altered Intercellular Communication	The strength and direction of the associations between inflammation and coagulation biomarkers with kidney disease onset and progression remain unclear, especially in a population-based setting.	22560844
Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation and coagulation biomarkers are associated with decreasing kidney function in ambulatory adults without established cardiovascular disease or chronic kidney disease.	22560844
Inflammation, Fibrosis Assessment, Retroperitoneal fibrosis	Altered Intercellular Communication	Idiopathic retroperitoneal fibrosis is an uncommon disease characterized by encasement of retroperitoneal structures by fibrosis and chronic inflammation.	22561019
Cessation of life, Tumor necrosis	Altered Intercellular Communication	Tumour necrosis factor receptor (TNFR)-associated death domain (TRADD) protein is a central adaptor in the TNFR1 signalling complex that mediates both cell death and inflammatory signals.	22561347
Inflammation, Toxic effect	Altered Intercellular Communication	The most serious acute toxicity was irradiated inflammation of mocosa with Grade 1 to 4 of 16.7%, 60%, 23.3% and 0, respectively.	22561435
Inflammation, Granuloma	Altered Intercellular Communication	Regarding muscle histopathological findings, in addition to inflammation, 13 patients had chronic myopathic changes and six had granulomatous lesions.	22561642
Inflammation, Muscular Atrophy, Chronic disease, Myositis	Altered Intercellular Communication	Statistical analysis showed that the clinical features of a chronic disease course, cardiac involvement and muscle atrophy, and the histopathological features of chronic myopathic changes and granulomatous inflammation, were significantly more frequently observed in patients with anti-mitochondrial antibody-positive inflammatory myopathy than in patients who were negative for anti-mitochondrial antibodies.	22561642
Granulomatous inflammation, Muscular Atrophy, Chronic disease, Myositis	Altered Intercellular Communication	Our study revealed that inflammatory myopathies associated with anti-mitochondrial antibodies were frequently found in patients with the clinical features of a chronic disease course, muscle atrophy and cardiopulmonary involvement, and the characteristic histopathological feature of granulomatous inflammation.	22561642
Inflammation, Infiltration	Altered Intercellular Communication	sPPP attenuates alveolar inflammation, as demonstrated by the lower neutrophilic/lymphocytic alveolar infiltration, and the secretion of anti-inflammatory rather than proinflammatory mediators.	22561658
Inflammation, Carcinogenesis, Neoplasms	Altered Intercellular Communication	Intercellular adhesion molecule-1 (ICAM-1), a cell adhesion molecule with a key role in inflammation and immunosurveillance, has been implicated in carcinogenesis by facilitating instability of the tumor environment.	22562265
Myocarditis	Altered Intercellular Communication	Its relationship with active myocardial inflammation, however, is not well understood.	22562417
Inflammation, Fibrosis Assessment, Myocardial Infarction, Myocardial, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Myocardial edema as a feature of inflammation and myocardial necrosis or fibrosis can be frequently observed in patients with acute myocarditis by cardiovascular magnetic resonance (CMR).	22562417
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Progression of benign prostatic hyperplasia (BPH) involves chronic inflammation and immune dysregulation.	22562653
Hypogonadism, prostatitis	Altered Intercellular Communication	Preclinical studies have demonstrated that prostate inflammation and tissue remodeling are exacerbated by hypogonadism and prevented by testosterone supplementation.	22562653
Inflammation, Hypogonadism	Altered Intercellular Communication	Even after adjusting for confounding factors, hypogonadism was associated with a fivefold increased risk of intraprostatic inflammation, which was also more severe than that observed in eugonadal BPH patients.	22562653
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	In advanced osteoarthritis, when we consider that the inflammatory episodes are expected findings, the early confirmation of the inflammation on US may be particularly valuable in the clinical setting.	22562715
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	Endoscopic biopsies from the esophagus, gastroesophageal junction and stomach were evaluated for inflammation, the presence of H. pylori and intestinal metaplasia.	22563195
Inflammation, Sarcopenia, Obesity	Altered Intercellular Communication	It has been suggested that insulin resistance, low-grade inflammation and vitamin D deficiency are associated with obesity and sarcopenia.	22563924
Inflammation	Altered Intercellular Communication	Insulin resistance, inflammation and vitamin D deficiency were associated with SO in a Korean adult population.	22563924
Inflammation, Primary malignant neoplasm, Chronic disease	Altered Intercellular Communication	Biomarkers of low-grade systemic inflammation are used to study the associations of inflammation with chronic diseases, including cancer.	22564866
Inflammation	Altered Intercellular Communication	interleukin-17(+ve) T cells, exhibit increased exofacial redox-regulating enzymes and that peroxiredoxin 2 may be involved in the persistence of pro-inflammatory cells in chronic inflammation.	22565169
Proctitis, Intestinal Diseases	Altered Intercellular Communication	Surrogate markers of colorectal inflammation are increasingly being recognized as important in differentiating organic from functional intestinal disorders.	22565607
Inflammation	Altered Intercellular Communication	We evaluated FC as an index of inflammation in consecutive outpatients referred for colonoscopy for chronic, nonbloody diarrhea.	22565607
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	MRI histology correlation was high for delayed-phase MRI versus fibrosis stage (95% confidence interval [CI] 0.941 < r < 0.976, P = 5 x 10(-7)), but lower for all other comparisons (delayed-phase vs. inflammation and arterial-phase vs. inflammation or fibrosis all showed a CI no greater than 0.64).	22566123
Inflammation, Chronic Kidney Diseases, Diabetes Mellitus	Altered Intercellular Communication	Inflammation, diabetes, and chronic kidney disease: role of aerobic capacity.	22566996
Inflammation, Hypersensitivity, Candida (fungus)	Altered Intercellular Communication	Relationship between systemic inflammation and delayed-type hypersensitivity response to Candida antigen in older adults.	22567155
Inflammation	Altered Intercellular Communication	Research has shown that aging is associated with increased systemic inflammation as well as a reduction in the strength of immune responses.	22567155
Blood Vessel, Necrosis with inflammation	Altered Intercellular Communication	Churge-Strauss Syndrome belongs to systematic, necrotic inflammation of medium and small vessels diseases.	22568182
Eosinophilic disorder, Inflammation	Altered Intercellular Communication	Base for recognition was clinical picture and laboratory tests which showed elevetion of inflammation parameters (CRP, ESR), eosinophilia (18%) and p-ANCA antibodies.	22568182
Airway structure	Altered Intercellular Communication	Alveolar nitric oxide (CA(NO)) is a potential biomarker of small airway inflammation.	22568828
Necrotizing granulomatous inflammation, Inflammation	Altered Intercellular Communication	Xanthogranulomatous inflammation is a rare form of chronic granulomatous inflammation.	22568924
Oophoritis, Inflammation, Uterine Fibroids, Endometriosis of pelvis, Bacterial Infections, Xanthogranulomatous salpingitis	Altered Intercellular Communication	Chronic inflammation due to inadequate treatment of bacterial infection, coupled with pelvic endometriosis and uterine leiomyoma may have led to xanthogranulomatous salpingitis and oophoritis.	22568924
Inflammation, S100A4 protein, human	Altered Intercellular Communication	Complete removal is necessary to prevent fulminant inflammation and disorders of function; furthermore the risk of a malignant transformation is seldom but present.	22570008
Inflammation, No metabolic abnormalities, Impaired cognition	Altered Intercellular Communication	There is increasing evidence from basic science and human epidemiological studies that inflammation, oxidative stress, and metabolic abnormalities are associated with age-related cognitive decline and impairment.	22570133
Inflammation	Altered Intercellular Communication	Our findings also suggest that autophagy preserves arterial endothelial function by reducing oxidative stress and inflammation and increasing NO bioavailability.	22570377
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	The importance of chronic inflammation in atherogenesis and cytokine involvement in all stages of atherosclerotic plaque development is now obvious.	22570926
Lacrimal gland cyst, Inflammation, Traumatic injury	Altered Intercellular Communication	Lacrimal duct cyst is a rare clinical entity and has been postulated to result from localized inflammation or trauma to conjunctiva.	22571599
Tracheobronchitis, Pneumonitis, Edema, Pneumonia	Altered Intercellular Communication	Common findings included pulmonary interstitial inflammation and edema, tracheobronchitis, and pneumonia.	22571830
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	As a result of mucosal inflammation in ulcerative colitis, oxidative stress can occur.	22572519
Inflammation	Altered Intercellular Communication	Polymorphisms in 15 genes involved in inflammation or responses to oxidative stress were characterized in the subjects.	22572643
Carcinoma of lung, Pneumonitis	Altered Intercellular Communication	The expression level of GRIM-19 was significantly different between lung cancer and lung inflammation.	22573109
Carcinoma of lung, Pneumonitis	Altered Intercellular Communication	Furthermore, we found GRIM-19 to be primarily located in the cytoplasm in lung inflammation tissues, but located in the nucleus in lung cancer tissues.	22573109
Inflammation, Pain Distress Question	Altered Intercellular Communication	We describe two cases of peristomal inflammation which resulted in pain, poor adhesion of the stoma bag and faecal leaking.	22573469
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Multistage analysis of variants in the inflammation pathway and lung cancer risk in smokers.	22573796
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Variants in multiple genes in inflammation pathways may contribute to risk of lung cancer.	22573796
Inflammation, Carcinoma of lung	Altered Intercellular Communication	We therefore conducted a three-stage comprehensive pathway analysis (discovery, replication, and meta-analysis) of inflammation gene variants in ever-smoking lung cancer cases and controls.	22573796
Inflammation, Dental Plaque	Altered Intercellular Communication	Telomere and telomerase may play key roles in the etiological factors such as inflammation and AS plaque.	22574607
Inflammation	Altered Intercellular Communication	Obesity-related early systemic inflammation might be involved in suboptimal bone accrual, particularly in overweight girls.	22574856
Inflammation, Chronic disease	Altered Intercellular Communication	The discovery of a form of low-grade systemic and chronic inflammation ("metaflammation"), linked to inducers (broadly termed "anthropogens") associated with modern man-made environments and lifestyles, suggests an underlying basis for chronic disease that could provide a 21st-century equivalent of the germ theory.	22575080
Inflammation	Altered Intercellular Communication	The Medtronic RHS may induce less systemic inflammation than conventional CPB systems, particularly when cardiotomy suction was used, but it did not result in improved clinical benefit.	22576032
Colorectal Carcinoma	Altered Intercellular Communication	Inflammation-based prognostic system predicts postoperative survival of colorectal cancer patients with a normal preoperative serum level of carcinoembryonic antigen.	22576063
Primary malignant neoplasm	Altered Intercellular Communication	On the other hand, inflammation-based prognosis, assessed by the Glasgow Prognostic Score (GPS), has been established as one of the important prognostic factors of survival after surgery for several types of cancer.	22576063
Inflammation, Breast Carcinoma, Obesity	Altered Intercellular Communication	These findings help to explain the link among obesity, low-grade chronic inflammation, and breast cancer with important clinical implications.	22576212
Inflammatory Bowel Diseases, Inflammation, Rheumatoid Arthritis, Spondylitis	Altered Intercellular Communication	Mean platelet volume (MPV) is inversely correlated with inflammation in inflammatory bowel diseases, rheumatoid arthritis, and ankylosing spondylitis as shown in the previous studies.	22576316
ARCN1 gene, Inflammation	Altered Intercellular Communication	The results suggest that assessment of MPV in COPD exacerbation may indicate systemic inflammation.	22576316
Inflammation, Lymphoma	Altered Intercellular Communication	[Malignant lymphoma presenting as inflammation of unknown origin].	22576571
Inflammation, Rheumatism	Altered Intercellular Communication	We classified underlying diseases presenting as inflammation of unknown origin in division of rheumatic diseases.	22576571
Inflammation, Rheumatism	Altered Intercellular Communication	ML ranked first among causes of inflammation of unknown origin at the division of Rheumatic Diseases, and FDG-PET/CT proved to be useful for biopsy site selection.	22576571
Nausea, Bothered by Vomiting, Headache, physiopathological	Altered Intercellular Communication	Its clinical symptoms are characterized by sudden onset of headache, nausea, vomiting, ophthalmic symptoms and hormonal dysfunction.	22576705
Myocarditis	Altered Intercellular Communication	Pericardial VEGF levels correlated positively with markers of pericardial inflammation, whereas pericardial bFGF levels showed a negative correlation.	22577248
Inflammation, Vasculitis, CTCAE, Endothelial dysfunction, Cardiovascular system	Altered Intercellular Communication	This is a rare generalized systemic vasculitis typical of the early childhood characterized by inflammation and endothelial dysfunction with a high risk for cardiovascular fatal events.	22578402
Inflammation, Lymphoma	Altered Intercellular Communication	[Lymphoma suspected cervical lymph node inflammation indicating secondary syphilis].	22579090
Inflammation	Altered Intercellular Communication	Initial fine needle aspirations and the following extirpation of a cervical lymph node revealed severe chronic inflammation.	22579090
Inflammation, Venous Thromboembolism, vinyltriethoxysilane	Altered Intercellular Communication	The pathogenesis of venous thromboembolism (VTE) is linked to inflammation and oxidant production, although specific markers for these pathways with pathological relevance to VTE have not been explored.	22580301
Inflammation, vinyltriethoxysilane	Altered Intercellular Communication	Therefore, nitrated fibrinogen may serve as a marker of inflammation and oxidative stress in VTE.	22580301
Inflammation, vinyltriethoxysilane	Altered Intercellular Communication	These data indicate that nitrated fibrinogen is an oxidative risk marker in VTE, providing a novel mechanistic link between oxidant production, inflammation, and VTE.	22580301
Vascular System Injuries, Inflammation, Atherosclerosis	Altered Intercellular Communication	Osteopontin (OPN) is a multifunctional protein associated with vascular injury and has been linked to atherosclerosis and inflammation.	22580396
Inflammation, Knee pain	Altered Intercellular Communication	Systemic inflammation is an independent predictor of worsening knee pain over 5 years.	22580582
Inflammation, Fibrosis Assessment, Malignant Neoplasms	Altered Intercellular Communication	Inhaled asbestos fibres are known to cause inflammation processes with the result of lung or pleural fibrosis and malignancies.	22580886
SLC5A8 wt Allele, Thyroiditis	Altered Intercellular Communication	The results indicate that TPOAb titer is associated with the degree of thyroid inflammation and that detection of TPOAb is a very specific means of diagnosing AIT.	22581205
Sepsis, Communicable Diseases, Inflammation	Altered Intercellular Communication	A classification model comprising these markers resulted in 80% and 70% correct classifications in a training set and a test set, respectively.This study demonstrates that acylcarnitines and glycerophosphatidylcholines may be helpful for differentiation of infectious from noninfectious systemic inflammation due to their significantly higher concentration in sepsis patients.	22581935
ARCN1 gene, Inflammation	Altered Intercellular Communication	At 1 year it decreased, never reaching normal values in the majority of our patients thus confirming the presence of a persistent inflammation in COPD.	22582486
Infarction, Inflammation, Blood Clot, Rupture	Altered Intercellular Communication	All tissue material was resectioned and stained with the immunohistochemical reagent, cytokeratin (AE1/AE3/PKC26), and that made it possible to divide the material into two different disease categories: (1) 36 biopsies from 30 cases had tissue inflammation after rupture of keratin-rich epidermal cysts, which we call 'horny cell inflammation', followed by extensive cutaneous thrombi and infarcts, and (2) 21 biopsies from 20 cases had 'apocrinitis' defined here as an inflammatory destruction of apocrine skin glands, and partly of close eccrine glands.	22583355
Inflammation	Altered Intercellular Communication	There were significant transient cardiac surgery-related fluctuations in 1,25-dihydroxyvitamin D and the aforementioned parameters of mineral metabolism, inflammation, and immune status.	22584760
Pain Distress Question, Inflammation, Primary gout, Exacerbation of cGVHD	Altered Intercellular Communication	Canakinumab provided significant pain and inflammation relief and reduced the risk of new flares in these patients with acute gouty arthritis.	22586173
Acute and chronic inflammation	Altered Intercellular Communication	A prospective comparative study with a pre-post design has been performed consecutively enrolling 33 (males 70 %) patients of both genders older than 12 years of age, affected by chronic sinonasal inflammation.	22588193
Inflammation, Necrosis	Altered Intercellular Communication	Typically, a pattern of acute inflammation occurs, with a predominantly lymphoid cellular infiltrate followed by necrosis.	22588424
Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	The effect of prostate tissue inflammation in benign prostatic hyperplasia on enhancer of zeste homolog 2 ribonucleic acid expression.	22588437
prostatitis	Altered Intercellular Communication	This supports the possible involvement of EZH2 mRNA overexpression in the development of prostate inflammation, and its new regulatory role in suppressing the expression of some inflammatory network genes.	22588437
Inflammation, Heart failure, Muscle Cells	Altered Intercellular Communication	We hypothesized that outdoor temperature in the Boston, Massachusetts, area (1- to 4-day moving averages) would be associated with higher levels of biomarkers of inflammation and myocyte injury in a repeated-measures study of individuals with stable heart failure.	22588803
Macular edema due to diabetes mellitus, dimethyl ether	Altered Intercellular Communication	Inflammation contributes significantly to the pathogenesis of diabetic macular edema (DME).	22589436
MIRLET7E gene	Altered Intercellular Communication	Among these, four microRNAs (hsa-miR-1, hsa-let-7e, hsa-miR-9, and hsa-miR-182) were known to be associated with the inflammatory signaling pathway.	22589448
Airway structure, Parenchyma, ARCN1 gene	Altered Intercellular Communication	These data suggest that cigarette smoke augments the expression and responses of TLR3 in human macrophages, and this may contribute to neutrophilic airway inflammation and parenchymal destruction in the lungs of smokers and patients with COPD.	22591330
Inflammation, Ischemic stroke	Altered Intercellular Communication	This stroke-specific gene expression profiling provides valuable information about the role of peripheral inflammation to the pathophysiological mechanism of ischemic stroke.	22591946
Inflammation	Altered Intercellular Communication	It is suggested that analysis of PISF may serve for detection of inflammation.	22592038
Inflammation	Altered Intercellular Communication	Our adolescent data suggest that greater consumption of dietary fiber is associated with lower visceral adiposity and multiple biomarkers implicated in inflammation.	22593589
Inflammation	Altered Intercellular Communication	Short-chain fatty acids (SCFAs) are important metabolic products of subgingival organisms and their concentrations are associated with the status of inflammation.	22594616
Trachoma	Altered Intercellular Communication	This integrated mapping was followed by a 20-cluster trachoma survey in each district that surpassed the WHO-defined threshold of 10% prevalence of trachomatous inflammation-follicular (TF).	22594642
Ischemia, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	These include ischemia and inflammation, pre-cancer and cancer.	22594983
Degenerative polyarthritis, Inflammation, Cartilage damage	Altered Intercellular Communication	Serum adipokines in osteoarthritis; comparison with controls and relationship with local parameters of synovial inflammation and cartilage damage.	22595228
Degenerative polyarthritis, Inflammation, Cartilage damage	Altered Intercellular Communication	The aim of this study is to compare serum adipokine levels between end-stage knee OA patients and controls and to relate these serum levels to local parameters of cartilage damage and synovial inflammation.	22595228
Inflammation, Degenerative disorder of cartilage	Altered Intercellular Communication	Cartilage and synovial tissue were collected at TKR surgery and assessed for cartilage degeneration and synovial inflammation by histochemistry and biochemical analyses.	22595228
Inflammation, Cartilage damage	Altered Intercellular Communication	No associations between serum levels of adipokines and cartilage damage (histochemistry, proteoglycan content) were found whereas weak but positive associations with synovial inflammation were found [adiponectin and interleukin-1b (IL-1b), stand beta = 0.172, P = 0.02; resistin and histology, stand beta = 0.183, P = 0.034, adjusted for demographics].	22595228
Degenerative polyarthritis, Inflammation, Cartilage damage	Altered Intercellular Communication	Associations of systemic adipokines with local synovial tissue inflammation were found, although not represented by similar relations with cartilage damage, suggesting that adipokines are of relevance in the inflammatory component of OA.	22595228
Inflammation, Ulceration, CTCAE, S100A4 protein, human, Gastric Adenoma	Altered Intercellular Communication	Gastric adenomyoma is usually asymptomatic but could cause obstruction, inflammation, ulceration, and malignant transformation.	22595594
Parkinson Disease, Tremor, CTCAE 3.0	Altered Intercellular Communication	We hypothesize that the serotonin neurotransmission system may also play a role as it does in tremor in Parkinson disease.	22595620
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Male sex hormones and systemic inflammation in Alzheimer disease.	22596080
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Male sex hormones and systemic inflammation in Alzheimer disease.	22596080
Autoimmune Diseases, Inflammation, Lymphoma	Altered Intercellular Communication	Marginal zone lymphomas are indolent B-cell lymphomas associated with autoimmunity and chronic inflammation.	22596180
Inflammation, Discitis, Bone structure of thoracic vertebra, Edema	Altered Intercellular Communication	Urgent MRI showed discitis at the disc between cervical vertebra seven (C7), thoracic vertebra one (T1) and lumbar vertebra three and four (L3-4), associated dural inflammation, stenosis of the cervical spinal canal and cervical cord oedema at the level of C3.	22605834
Ulcer, Granulomatous inflammation, Stenosis, Granuloma	Altered Intercellular Communication	Biopsy of the stricture revealed ulcer with granulomatous inflammation including well-formed granulomas and an infiltrate of histiocytes within the lamina propria.	22605846
Inflammation	Altered Intercellular Communication	Gene ontology analysis indicated that the over-expressed genes in CD90(+)CSCs were associated with inflammation, drug resistance and lipid metabolism.	22606345
Structure of temporalis muscle, Traumatic injury, Aplasia/Hypoplasia of the mandible	Altered Intercellular Communication	There are multiple theories as to the causes of coronoid process hyperplasia of the mandible, including trauma, temporalis muscle hyperactivity, hormonal stimulus, and genetic inheritance.	22606859
Inflammation, Anemia	Altered Intercellular Communication	Relationship between markers of inflammation and anaemia in children of Papua New Guinea.	22607654
Inflammation, Anemia	Altered Intercellular Communication	There are no expert group recommendations on whether to or how to account for markers of inflammation in presenting results on anaemia prevalence.	22607654
ARCN1 gene, Coughing, Airway structure	Altered Intercellular Communication	COPD is characterized by increased cough, mucus production, and airway inflammation.	22608352
Inflammation, Electrocardiogram: myocardial infarction (finding), Coronary Arteriosclerosis	Altered Intercellular Communication	With the growing understanding of the role of inflammation in patients with atherosclerotic disease, studies have focused on high-sensitivity C-reactive protein (hs-CRP) and other inflammatory markers in their association with outcomes in ST-segment elevation myocardial infarction.	22608360
Inflammation, Certified Midwife	Altered Intercellular Communication	Cryptococci and inflammation in the central nervous system may play important roles in the pathogenesis of CM.	22608531
Inflammation	Altered Intercellular Communication	Low intensity of inflammation and effective surgical CSF drains for increased intracranial pressure and cryptococci removal may contribute to lower mortality in HIV-infected patients.	22608531
Inflammation, Infection	Altered Intercellular Communication	One year of pomegranate juice intake decreases oxidative stress, inflammation, and incidence of infections in hemodialysis patients: a randomized placebo-controlled trial.	22609423
Inflammation, Atherosclerosis	Altered Intercellular Communication	Increased systemic inflammation and oxidative stress are well established as nontraditional key players in the pathogenesis of atherosclerosis and are also involved in the innate immunity dysregulation in hemodialysis (HD) patients.	22609423
Inflammation, Lupus Erythematosus, Systemic, Autoimmune Diseases, Refractory anemias, Tumor necrosis, Rheumatoid Arthritis, Lupus Erythematosus	Altered Intercellular Communication	Many cytokines are involved in the pathogenesis of autoimmune diseases and are recognized as relevant therapeutic targets to attenuate inflammation, such as tumor necrosis factor (TNF)-a in rheumatoid arthritis (RA) and interferon (IFN)-a/g in systemic lupus erythematosus (SLE).	22610275
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Excessive apoptosis and prolonged inflammation of alveolar cells are associated with the pathogenesis of pulmonary emphysema.	22610351
Inflammation, Postoperative Complications, Corneal edema	Altered Intercellular Communication	Postoperative complications included corneal edema (2 eyes), Descemet folds (1 eye), intraocular pressure elevations (3 eyes), and pronounced anterior segment inflammation (1 eye).	22610720
Liver carcinoma, Communicable Diseases, Hepatitis C, Acute and chronic inflammation, FAM126A gene	Altered Intercellular Communication	Hepatitis C virus (HCV) infection usually induces chronic hepatic inflammation, which favors the initiation and progression of hepatocellular carcinoma (HCC).	22610915
Inflammation	Altered Intercellular Communication	Moreover, microRNA-155 (miR-155) plays an important role in regulating both inflammation and tumorigenesis.	22610915
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	However, little is known about whether and how miR-155 provides the link between inflammation and cancer.	22610915
Inflammation	Altered Intercellular Communication	This could be attributed to the oxidative stress, inflammation neuronal apoptosis and an alteration in the activities of the signaling enzymes.	22610977
Inflammation, Thrombosis, Communicable Diseases, Damage, Thrombocytopenia	Altered Intercellular Communication	Recent studies suggest that DNA and histones are released during inflammation or infection and stimulate coagulation, thrombosis, thrombocytopenia, and organ damage in mice.	22611154
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histological inflammation grading and fibrosis staging were evaluated by H and E staining and Van Gieson's method.	22611323
Inflammation, Chronic small plaque psoriasis, Psoriasis	Altered Intercellular Communication	To explore the possible role of osteopontin (OPN) in chronic plaque psoriasis and understand the role of inflammation in psoriasis.	22611763
Disability or Permanent Damage, Traumatic	Altered Intercellular Communication	The extent of irreversible neuroaxonal damage is the key determinant of permanent disability in traumatic and inflammatory conditions of the central nervous system (CNS).	22612622
Inflammation, Pustulosis of Palms and Soles	Altered Intercellular Communication	Alitretinoin abrogates innate inflammation in palmoplantar pustular psoriasis.	22612660
Atherosclerosis	Altered Intercellular Communication	These data indicates that ABCA1, ABCG1, and SR-BI are reduced in various populations under subclinically inflammatory conditions, which may potentially lead to impairing reverse cholesterol transport and developing atherosclerosis.	22614118
Inflammation, Primary malignant neoplasm, Hypoproteinemia	Altered Intercellular Communication	Circulating myeloid-derived suppressor cells are increased and correlate to immune suppression, inflammation and hypoproteinemia in patients with cancer.	22614133
malignant disease, Inflammation	Altered Intercellular Communication	It has been reported that MDSCs are generated by malignant diseases or inflammation.	22614133
Inflammation, Hypoproteinemia	Altered Intercellular Communication	These data also suggest that they are related to chronic inflammation and that their levels are increased further in the terminal stages of patients whose nutritional status is impaired as observed in hypoproteinemia.	22614133
Inflammation	Altered Intercellular Communication	Furthermore, the inflammation score was significantly higher in H. pylori-infected del/del homozygotes compared to ins carriers.	22614238
Airway structure, Inflammation, Respiration Disorders	Altered Intercellular Communication	Although airway inflammation begins early in life in children with chronic respiratory diseases, current methods to assess this inflammation are invasive and entail significant risk.	22615171
Airway structure	Altered Intercellular Communication	The EBC AMP/Ado ratio correlates with measures of infant lung function and may be a less invasive means of monitoring airway inflammation in this population.	22615171
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	This pilot clinical trial identified the oral microflora of the peri-implant sulcus of cancer patients with jaw reconstruction and compared sites with and without clinical signs of inflammation.	22616064
Communicable Diseases, Colonization, allergic inflammation	Altered Intercellular Communication	It remains unanswered whether persistent allergic inflammation in nasal mucosa alters bacterial colonization and infection.	22616074
Pancreatic carcinoma	Altered Intercellular Communication	Inflammation marker and risk of pancreatic cancer: a nested case-control study within the EPIC cohort.	22617158
Inflammation	Altered Intercellular Communication	We hypothesized that increased RDW would be associated with isolated CAE because both are associated with inflammation.	22619398
Inflammation, Sclerosing peritonitis	Altered Intercellular Communication	Sclerosing peritonitis: a rare but fatal complication of peritoneal inflammation.	22619486
Inflammation, Sclerosing peritonitis	Altered Intercellular Communication	Sclerosing peritonitis is a rare form of peritoneal inflammation with an often fatal outcome.	22619486
Tuberculoma, Inflammation, Tuberculosis	Altered Intercellular Communication	The histopathological report was caseating granulomatous inflammation involving cerebellar parenchyma; suggestive of tuberculoma, PCR for M. Tuberculosis complex, using brain tissue from formalin-fixed paraffin-embeded block, yields positive result for M. Tuberculosis complex.	22619899
Lichen - organism, Inflammation, Localized scleroderma, Systemic Scleroderma	Altered Intercellular Communication	Histopathologically, perineural inflammation was observed in 49% of cases, and may serve, in addition to other features including lichen sclerosis-like changes (observed in exclusively nine cases of morphea), more diffuse dermal and less subcutaneous sclerosis, and intense inflammation, as clues favouring diagnosis of morphea over systemic sclerosis.	22620486
Lichen - organism, Inflammation, Localized scleroderma, Systemic Scleroderma	Altered Intercellular Communication	Histopathologically, perineural inflammation was commonly observed and may serve in addition to lichen sclerosis-like changes and intense inflammation as clues favouring diagnosis of morphea over systemic sclerosis.	22620486
Inflammatory abnormality of the eye, Dryness of eye	Altered Intercellular Communication	Patients with severe dry eye or any other condition that induces ocular inflammation were excluded.	22620852
Bacteremia, Meningitis	Altered Intercellular Communication	Mutant bacteria also induced markedly reduced meningeal inflammation and brain pathology compared with wild type, despite similar levels of bacteremia.	22622042
Inflammation	Altered Intercellular Communication	L-carnitine plays a critical role in fatty acid transport into the mitochondria and may thus influence inflammation and myocardial function.	22622056
Inflammation, Fibrosis Assessment, Atrial Fibrillation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Fibrosis and inflammation may play a significant role in the pathogenesis of atrial fibrillation (AF) recurrence.	22622138
Inflammation, Hyperglycemia	Altered Intercellular Communication	Low-grade inflammation in young adults exposed to intrauterine hyperglycemia.	22622155
Hyperglycemia, Inflammation, Overweight	Altered Intercellular Communication	Maternal overweight but not exposure to intrauterine hyperglycemia was associated with low-grade inflammation in adult offspring.	22622155
Inflammation, Neoplasms	Altered Intercellular Communication	Transient systemic inflammation accompanying surgery could be part of the metastatic tumor seeding process and could have been effectively blocked by perioperative anti-inflammatory agents.	22622810
Inflammation, Metabolic Syndrome X, MS gene	Altered Intercellular Communication	The metabolic syndrome (MS) is characterized by chronic inflammation.	22623143
Airway structure, Asthma	Altered Intercellular Communication	A high fraction of nitric oxide in exhaled breath (FeNO) has been suggested to be a marker of ongoing airway inflammation and poorly controlled disease in asthma.	22624949
Inflammation	Altered Intercellular Communication	Chronic inflammation as predictor of 1-year hospitalization and mortality in elderly population.	22624958
Inflammation	Altered Intercellular Communication	Systemic low-grade inflammation is thought to be associated with an increased risk of adverse clinical outcomes in elderly population.	22624958
Inflammation	Altered Intercellular Communication	Protein expression differences were found in debris from patients with high systemic inflammation compared with debris from patients with low systemic inflammation.	22626270
Crypt abscess, Ulcerative Colitis, Edema, Ulcer, Crypt, Erythema, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Their ileocolonoscopy showed diffuse mucosal erythema, oedema, friability and multiple irregular ulcers, and histopathological examination of colonic specimen revealed diffuse chronic mucosal inflammation, crypt distortion and crypt abscesses suggesting ulcerative colitis.	22626504
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	Inflammatory bowel disease, a chronic inflammation of the intestinal tract, presents in two variations, Ulcerative Colitis (UC) and Crohn's disease (CD).	22626506
Bronchial Hyperreactivity, Airway structure, AHR wt Allele, MS4A2 wt Allele, Asthma	Altered Intercellular Communication	We investigated the association between genetic variation in this region with asthma, lung function, airway inflammation, hyperresponsiveness (AHR), and atopy in a case-control study of United Kingdom adults.	22626592
Inflammation, Postoperative Period, Endothelial dysfunction, Obesity	Altered Intercellular Communication	Obesity increases oxidative stress, endothelial dysfunction, and inflammation, but the effect of obesity on postoperative AKI is not known.	22626819
Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation is closely associated with cardiovascular disease, the leading cause of mortality in patients with CKD.	22626963
Inflammation, Osteolysis, Necrosis, Failure (biologic function)	Altered Intercellular Communication	Therefore, peri-implant osteolysis in early TAR implant failure seems to be caused by the RANKL-driven chronic foreign body inflammation directed against, not implant-derived particles, but against necrotic autologous tissues.	22627031
Inflammation, Interstitial inflammation	Altered Intercellular Communication	Histopathologic examination (n = 14) showed predominantly neutrophilic perivascular and interstitial inflammation (57%) or predominantly mononuclear cell perivascular inflammation (29%), with eosinophils in 50% of cases.	22627038
Inflammation, Duodenitis, Esophagitis	Altered Intercellular Communication	Gastrointestinal endoscopy and biopsies revealed esophagitis with some eosinophils and duodenitis with eosinophilic inflammation.	22627372
Inflammatory Bowel Diseases, Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Type of IBD, gender, concomitant PSC, pseudopolyps, extent of inflammation, and medication use were not related to early CRC (p > 0.05).	22627504
Inflammation	Altered Intercellular Communication	Magnetic resonance imaging revealed inflammation around the sacroiliac joint with abscess formation.	22627656
Granulomatosis, Inflammation, Systemic Vasculitis	Altered Intercellular Communication	Granulomatosis with polyangiitis involves sustained mucosal inflammation that is rich in B-cell survival factors and autoantigen.	22627727
Airway structure	Altered Intercellular Communication	Elevated fractional excretion of exhaled nitric oxide (FENO) reflects airway inflammation, but few studies have established its normal values.	22628492
Refractory anemias, Arthritis, Cartilage damage, Damage	Altered Intercellular Communication	These results suggest a role of DC2C/CPII as a marker of ongoing structural joint damage with the least association with CRP, and that irreversible cartilage damage in established RA limits restoration of the C2C/CPII level, even with tight control of joint inflammation.	22629396
Icterus, Inflammation, Fibrosis Assessment, Biliary calculi	Altered Intercellular Communication	According to Courvoisier's law; if gallbladder is palpable in a jaundiced patient, it is unlikely to be due to gallstones, because stones would have given rise to chronic inflammation and subsequently fibrosis of gallbladder therefore, rendering it incapable of dilatation.	22630101
Retinal Detachment, Choroidal Detachment, Inflammation, Uveal Effusion Syndrome	Altered Intercellular Communication	Uveal effusion syndrome is characterized by annular ciliochoroidal detachment, shifting non-rhegmatogenous retinal detachment, unremarkable inflammation in the anterior eye segment and normal intraocular pressure.	22630106
Barrett Esophagus, Inflammation	Altered Intercellular Communication	The role of inflammation both in the development and in the advance of Barrett's esophagus (BE) has not been elucidated.	22630608
Inflammation, Esophagitis	Altered Intercellular Communication	Previous diagnosis of esophagitis correlated to the degree of inflammation.	22630608
Pain Distress Question, Blurred vision, Inflammation	Altered Intercellular Communication	In all, 90.7% of the patients presented with blurred vision, and 25.6% with pain or inflammation.	22633214
Inflammation, Total abdominal hysterectomy, Hemolysis (biological function)	Altered Intercellular Communication	The association of hemolysis, ineffective erythropoiesis, and inflammation with the TAH warrants further study.	22633300
Inflammation	Altered Intercellular Communication	These findings indicate an important interaction between sex and inflammation in the healing response of vein grafts for LEB.	22633420
vascular inflammations, Cardiovascular Diseases	Altered Intercellular Communication	Insulin and leptin are important markers of insulin resistance and vascular inflammation in metabolic and cardiovascular diseases.	22633795
Inflammation, Malnutrition	Altered Intercellular Communication	Malnutrition is common in dialysis patients and is attributed to decreased food intake, and/or chronic systemic inflammation linked to dialysis-related comorbidities and complications.	22633989
Intraocular inflammation, Pain Distress Question, Hyperemia	Altered Intercellular Communication	Decreased visual acuity, intraocular inflammation, pain and conjunctival hyperemia were found in all patients.	22634027
Inflammation, Neoplasms	Altered Intercellular Communication	Immunohistochemical assessment of markers of inflammation, cell cycle, and apoptosis was carried out on tumor biopsies.	22634319
Inflammation, Metabolic Syndrome X, Atherosclerosis	Altered Intercellular Communication	Prediction of vascular events in subjects with subclinical atherosclerosis and the metabolic syndrome: the role of markers of inflammation.	22634975
Inflammation, Atherosclerosis	Altered Intercellular Communication	These findings confirm a worst vascular outcome in subjects with more criteria for the diagnosis of the MS and further suggest the need of future research to understand the combined role of inflammation and the MS in the progression from subclinical to clinical atherosclerosis.	22634975
Inflammation, Observation Method - Coagulation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Patterns of markers of inflammation, coagulation and vasoconstriction during follow-up of abdominal aortic aneurysms.	22634983
Inflammation, Observation Method - Coagulation, Aortic Aneurysm, Abdominal, Endothelial dysfunction, APP gene	Altered Intercellular Communication	The etiology of abdominal aortic aneurysm (AAA) includes inflammation, coagulation, and endothelial dysfunction.	22634983
Inflammation, Antiphospholipid Syndrome	Altered Intercellular Communication	8-isoprostane, prostaglandin E2, C-reactive protein and serum amyloid A as markers of inflammation and oxidative stress in antiphospholipid syndrome: a pilot study.	22638905
Inflammation, Antiphospholipid Syndrome	Altered Intercellular Communication	To test the inflammation and oxidative stress hypothesis in antiphospholipid syndrome (APS) patients and to identify possible associations with clinical and laboratory features of the disease.	22638905
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP) is a central component of innate immune defenses, and high sensitivity CRP has emerged as an important biomarker of chronic inflammation and cardiovascular disease risk.	22639072
Inflammation	Altered Intercellular Communication	The application of current guidelines for the assessment of chronic inflammation failed to detect a single case of "high risk" CRP.	22639072
Inflammation	Altered Intercellular Communication	It documents a pattern of variation over time that is distinct from prior research, with no evidence for chronic low-grade inflammation.	22639072
Inflammation	Altered Intercellular Communication	These results may have substantial implications for research on inflammation and diseases of aging globally, as well as for scientific understandings of the regulation of inflammation.	22639072
Hashimoto Disease, Inflammation, Haiti	Altered Intercellular Communication	The relationship between inflammation, Hashimoto's thyroiditis (HT) and insulin resistance is still controversial.	22639339
Inflammation, Metabolic Syndrome X, Bipolar Disorder	Altered Intercellular Communication	Depressive symptoms in older people with metabolic syndrome: is there a relationship with inflammation?	22639424
Inflammation, ETV3 wt Allele, Bipolar Disorder	Altered Intercellular Communication	MetS and inflammation are independently associated with depressive symptoms in older people.	22639424
Inflammation	Altered Intercellular Communication	Low-grade chronic inflammation and superoxide anion production by NADPH oxidase are the main determinants of physical frailty in older adults.	22640231
Inflammation	Altered Intercellular Communication	Low-grade chronic inflammation and oxidative stress, mediated partly by the superoxide anion produced by NADPH oxidase, are closely linked and could be involved in age-related physical decline.	22640231
Inflammation	Altered Intercellular Communication	Superoxide production and inflammation markers, such as fibrinogen, were more important in slow walkers (p = 0.004 and p = 0.006, respectively).	22640231
Inflammation	Altered Intercellular Communication	Physical frailty in older people is associated with superoxide anion overproduction by NADPH oxidase and low-grade chronic inflammation.	22640231
Inflammation	Altered Intercellular Communication	Omega-3 supplementation lowers inflammation in healthy middle-aged and older adults: a randomized controlled trial.	22640930
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Observational studies have linked lower levels of omega-3 (n-3) polyunsaturated fatty acids (PUFAs) with inflammation and depression.	22640930
Inflammation, Overweight	Altered Intercellular Communication	Our data suggest that n-3 PUFAs can reduce inflammation in overweight, sedentary middle-aged and older adults, and thus could have broad health benefits.	22640930
Ischemia, Inflammation, Urinary bladder sphincter dysfunction	Altered Intercellular Communication	Involvement of TL1A and DR3 in induction of ischaemia and inflammation in urinary bladder dysfunction in the elderly.	22641456
Detrusor instability, Inflammation, Bladder dysfunction, Ischemia	Altered Intercellular Communication	Bladder dysfunction due to detrusor instability (caused by old age) is considered to be associated with chronic ischaemia and inflammation.	22641456
Inflammation	Altered Intercellular Communication	CRP association with ICT/SEC suggests that inflammation plays a role in ICT/SEC formation.	22641545
Blood Clot, Thrombophilia	Altered Intercellular Communication	Intra-cardiac thrombus (ICT) and spontaneous echo contrast (SEC) are considered hypercoagulable and inflammatory conditions.	22641545
Inflammation, Postthrombotic Syndrome	Altered Intercellular Communication	Markers of coagulation, fibrinolysis and inflammation in relation to post-thrombotic syndrome.	22642402
Inflammation, Thrombophilia	Altered Intercellular Communication	Persistent inflammation rather than hypercoagulability might be the most important etiological factor in PTS, and may be a target for future therapy.	22642402
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	YKL-40, a proposed marker of inflammation and endothelial dysfunction, is associated with atherosclerosis and an increased cardiovascular mortality in the general population.	22642467
Inflammation, Scleritis, Episcleritis	Altered Intercellular Communication	Initial inflammation control was achieved in 78-81% of scleritis patients and 73-80% episcleritis patients on COXIs (p > .05).	22642498
Abdominal Cramps	Altered Intercellular Communication	The relationship between abdominal cramps and hot flushes may be hormonal or sociocultural.	22642878
Meningioma, Hormone abnormality, Visual disturbance	Altered Intercellular Communication	Sellar meningiomas are technically challenging and carry a high risk for visual disturbance and pituitary hormonal abnormalities.	22644157
Adult Non-Hodgkin Lymphoma, Pseudolymphoma, Immunoglobulin G4-Related Disease, Orbital Pseudotumor	Altered Intercellular Communication	The breakdown of the 71 cases was: 45 cases of non-Hodgkin lymphoma, 16 cases of IgG4-ROD, 5 cases of reactive lymphoid hyperplasia, and 5 cases of idiopathic orbital inflammation.	22644450
Inflammatory Bowel Diseases, Inflammation, Weight decreased, Ulceration, CTCAE	Altered Intercellular Communication	This study reports the case of a 15-year-old male patient with extensive anal inflammation, cobblestone-like mucosa and areas of ulceration, loose bloody stool and weight loss for 8 weeks, suggestive of inflammatory bowel disease.	22645392
Chronic lymphocytic inflammation, Pontine structure	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids following influenza vaccination.	22646278
Chronic lymphocytic inflammation, Pontine structure, Clippers	Altered Intercellular Communication	We present the case of a patient with a newly described inflammatory process that primarily involves the pons and adjacent structures, which is called chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS).	22646278
Inflammation, Edema, Pain Distress Question	Altered Intercellular Communication	Complications such as mild edema, inflammation and pain were noted in three patients, which resolved within few days.	22646527
Presenile dementia, Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation has been associated with Alzheimer's disease (AD) and dementia.	22647255
Angiodysplasia, Inflammation	Altered Intercellular Communication	There are a variety of additional endoscopic IRC therapeutic utilities: endoscopic management of angiodysplasia, inflammation, hemostasis, and NOTES applications.	22648099
Hepatic inflammation, Hepatocarcinogenesis	Altered Intercellular Communication	Dietary long-chain fatty acid (LCFA) intake is an important risk factor for hepatic inflammation and hepatocarcinogenesis.	22648712
PHB2 gene, Communicable Diseases, Inflammation, Arthritis, Reactive	Altered Intercellular Communication	Reactive arthritis (ReA) is a sterile joint inflammation triggered by a remote infection and associated with human leucocyte antigen (HLA)-B27.	22651550
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is a pivotal process in the progression of atherosclerosis, which can be noninvasively imaged by FDG positron emission tomography (FDG-PET).	22651864
Eosinophilic cystitis	Altered Intercellular Communication	Eosinophilic cystitis is an inflammatory condition characterized by eosinophilic infiltration of whole layers of the bladder wall.	22652390
Inflammation, Anterior nares	Altered Intercellular Communication	The elevated levels of proinflammatory cytokines in NARES may indicate the chronic, self-perpetuating process of inflammation in NARES which seems to be more pronounced than in PAR.	22652688
Inflammation	Altered Intercellular Communication	Neutrophil gelatinase-associated lipocalin (NGAL), a protein involved in iron handling, has been recognized as a marker of inflammation.	22652747
Airway structure, Asthma	Altered Intercellular Communication	In asthmatic patients there is a relationship between EBC pH, ammonia and nitrite/nitrate concentrations and other recognized markers of airway inflammation.	22653320
Inflammation, Metabolic Diseases, Atherogenesis, Hypertension, CTCAE, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	It is thought that chronic inflammation results in metabolic diseases and proinflammatory cytokines give rise to the development of atherogenesis, peripheral insulin resistance, hypertension, and type 2 diabetes.	22654590
Pneumonitis, Neutrophil Infiltration	Altered Intercellular Communication	This Th2 bias and the eosinophilic reaction could be prevented by adding CpG to the vaccine formulation, which, however did not prevent pulmonary inflammation and neutrophil infiltration upon viral challenge.	22655066
Craniocerebral Trauma, Inflammation, Intracranial Hemorrhage, Meningitis, Chronic infectious disease, Traumatic injury, Pacchionian granulation	Altered Intercellular Communication	After tegmen dehiscence repair, ventriculoperitoneal shunting should be considered for patients with any combination of the following high-risk factors for recurrence: spontaneous CSF leak not caused by another predisposing condition (that is, trauma, chronic infections, or prior surgery), high-volume leaks, CSF opening pressure > 20 cm H(2)O, BMI > 30 kg/m(2), preoperative imaging demonstrating additional cranial base cortical defects (that is, contralateral tegmen or anterior cranial base) and/or an empty sella turcica, and any history of an event that leads to inflammation of the arachnoid granulations and impairment of CSF absorption (that is, meningitis, intracranial hemorrhage, significant closed head injury, and so forth).	22655695
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Increasing evidences have been obtained that immune activation and inflammation play critical roles in the pathogenesis of chronic heart failure (CHF).	22655909
Refractory anemias, Inflammation	Altered Intercellular Communication	It is, therefore, hypothesized that synovial TRAF6 is involved in the pathogenesis of synovial inflammation and osteoclast differentiation in RA.	22656185
Tumor necrosis	Altered Intercellular Communication	Tumor necrosis factor receptor-associated factor 6 (TRAF6) is one of the critical mediators both in inflammatory signal pathway and differentiation and resorption activity of osteoclasts.	22656185
Communicable Diseases, Inflammation	Altered Intercellular Communication	The number of dressing changes, incidence of blistering, leakage, appearance of inflammation, infection rate and the average stay in hospital was recorded for each patient.	22658450
Inflammation	Altered Intercellular Communication	The rate of inflammation and average length of stay in hospital was not significantly different between the two groups.	22658450
Inflammation	Altered Intercellular Communication	Surgical stress may cause excessive inflammation and lead to microcirculatory dysfunction.	22658494
Inflammation, Carotid Intima-Media Thickness	Altered Intercellular Communication	Low plasma testosterone and elevated carotid intima-media thickness: importance of low-grade inflammation in elderly men.	22658553
Inflammation	Altered Intercellular Communication	In elderly men, low plasma testosterone is associated with elevated carotid intima-media thickness only in those with low-grade inflammation.	22658553
palladium, Inflammation	Altered Intercellular Communication	The C8orf4 gene had small p values for both motor and cognitive outcomes, highlighting inflammation as a possible pathogenesis mechanism for progression in PD.	22658654
Inflammation, Neoplasms	Altered Intercellular Communication	Apart from previously recognized factors, such as histosubtype, tumor stage, and hemoglobin level difference, NLR, an index of systemic inflammation bears prognostic significance that shows that a snapshot of immune status is able to convey important prognostic information.	22658812
Inflammation, Etiology aspects, Colitis	Altered Intercellular Communication	"Pseudomembranous collagenous colitis" is a morphologic variant of collagenous colitis in which active inflammation with pseudomembrane formation is prominent and which has been associated with infectious, toxic, and ischemic etiologies.	22658854
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Bronchodilators modulate inflammation in chronic obstructive pulmonary disease subjects.	22659487
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by neutrophilic airway inflammation and oxidative stress.	22659487
Inflammation, Adolescence	Altered Intercellular Communication	From infancy to adolescence, critical illness seems to be a major determinant of midazolam clearance, which may result from reduced CYP3A4/5 activity due to inflammation.	22660604
Cartilage destruction, Inflammation, Refractory anemias	Altered Intercellular Communication	The positive association between S-COMP and ACPA suggests that these factors might interact, and could both be contributors to an unknown link between inflammation and cartilage destruction in patients with RA.	22660798
Airway structure, Rheumatoid Arthritis, Pulmonary Fibrosis	Altered Intercellular Communication	Improvements in cystic fibrosis lung disease and airway inflammation associated with etanercept therapy for rheumatoid arthritis: a case report.	22660986
TNF protein, human, Inflammation, Fibrosis Assessment, Tumor necrosis	Altered Intercellular Communication	Cystic fibrosis (CF) lung pathology is characterized by excessive neutrophilic inflammation and high tumor necrosis factor-alpha (TNF-a) levels.	22660986
Inflammation, Crohn Disease	Altered Intercellular Communication	To compare quantified terminal ileal (TI) motility during MR enterography (MRE) with histopathological severity of acute inflammation in Crohn's disease.	22661057
Inflammation	Altered Intercellular Communication	Wilcoxon rank sum test compared motility in subjects with and without histopathological inflammation.	22661057
Inflammation, Ischemia	Altered Intercellular Communication	New vessel formation contributes to organ development during embryogenesis and tissue repair in response to mechanical damage, inflammation, and ischemia in adult organisms.	22661514
Nephritis, Chronic Kidney Diseases	Altered Intercellular Communication	Indomethacin reduces glomerular and tubular damage markers but not renal inflammation in chronic kidney disease patients: a post-hoc analysis.	22662255
Airway structure, ARCN1 gene, Asthma	Altered Intercellular Communication	Sputum induction can be used as a non-invasive technique to investigate airway inflammation in asthma and COPD.	22662642
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Transbronchial lung biopsy revealed interstitial fibrosis, chronic inflammation and iron deposits.	22662643
Inflammation, Perforation (observation)	Altered Intercellular Communication	In the 4 months after the procedure, chronic inflammation of the retroperitoneal space caused a further perforation on the posterior wall of the aorta in the area of the bifurcation, distal to the graft.	22664288
Inflammation, Hyperplastic Polyp, atherosclerotic	Altered Intercellular Communication	The aim was to assess the release of MP and its association with inflammation and atherosclerotic burden.	22664782
Inflammation, ruptured disk, Hernia	Altered Intercellular Communication	Several possible aetiologies are also suggested, with disc rupture and inflammation followed by disc resorption and dural pocket formation being a possible mechanism predisposing to herniation at the extreme end of a clinicopathological spectrum.	22665931
Inflammation	Altered Intercellular Communication	Inflammation is a primary contributor to graft loss, and inhibiting pro-inflammatory cytokine activity can reverse inflammation mediated dysfunction of islet grafts.	22666480
Inflammation, atherosclerotic	Altered Intercellular Communication	Inflammation plays a crucial role in the progression of atherosclerotic plaques.	22669090
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	There were non-significant decreased risks with finasteride use (OR(adj advanced fibrosis) = 0.75, 95 % CI 0.39-1.45 and OR(adj advanced inflammation) = 0.74, 95 % CI 0.41-1.43).	22669204
Inflammation	Altered Intercellular Communication	White male methadone-users had 2.1-fold excess advanced inflammation risk (p = 0.15).	22669204
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Our preliminary study results suggest finasteride use is not significantly associated with a decreased risk of advanced hepatic fibrosis or inflammation in HCV+ males.	22669204
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The ethnically-divergent results for methadone associated fibrosis risk and finding of potentially increased inflammation risk in White males suggests the need for additional research.	22669204
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The histopathology report suggested inflammation with no evidence of malignancy.	22669871
Inflammation, Traumatic injury	Altered Intercellular Communication	No history of trauma was noted and he was systemically well with no clinical signs of acute inflammation.	22669928
polychondritis, Sweet Syndrome	Altered Intercellular Communication	Relapsing polychondritis and Sweet's syndrome are rare systemic inflammatory conditions.	22670004
Inflammation, diabetic	Altered Intercellular Communication	Within the limits of this study, our preliminary findings indicate that periodontal inflammation may influence circulating and GCF substance P levels in poorly controlled diabetic subjects.	22670254
Inflammation, Seborrheic dermatitis of scalp	Altered Intercellular Communication	Induced inflammatory genes were also enriched in dandruff uninvolved skin, suggesting the existence of predisposing factors associated with inflammation.	22670617
Inflammation	Altered Intercellular Communication	Systemic inflammation worsens outcomes in emergency surgical patients.	22673238
Inflammation	Altered Intercellular Communication	For surgeons whose practice is mostly elective, the significance of such systemic inflammation may be underappreciated.	22673238
Inflammation	Altered Intercellular Communication	This study sought to determine the influence of preoperative systemic inflammation on postoperative outcome in patients requiring emergent colon surgery.	22673238
Sepsis, Inflammation, Systemic Inflammatory Response Syndrome, Septic Shock	Altered Intercellular Communication	Four groups were defined by the presence and magnitude of the inflammatory response before operation: no inflammation, systemic inflammatory response syndrome (SIRS), sepsis, or severe sepsis/septic shock.	22673238
Inflammation	Altered Intercellular Communication	Thirty-day survival was significantly different (p < 0.0001) among the four groups; increasing magnitudes of preoperative inflammation had increasing probability of mortality (p < 0.0001).	22673238
Inflammation, Sepsis, Systemic Inflammatory Response Syndrome, Septic Shock, Cessation of life	Altered Intercellular Communication	Hazard ratios indicated that, compared with patients without preoperative systemic inflammation, the relative risk of death from SIRS was 1.9 (p < 0.0001), from sepsis was 2.5 (p < 0.0001), and from severe sepsis/septic shock was 6.7 (p < 0.0001).	22673238
Inflammation	Altered Intercellular Communication	Functional polymorphic sites in the promoter region of FCN1 regulate both the expression and synthesis of ficolin-1 and are associated with outcome in severe inflammation.	22673311
Inflammation, Ectopic ureter, Paratesticular mass	Altered Intercellular Communication	The patient was treated successfully with a radical orchiectomy and found to have ureteral ectopia inserting into the ipsilateral epididymis, resulting in this paratesticular mass caused by inflammation of the epididymis.	22673544
Inflammation	Altered Intercellular Communication	It is characterised by inflammation of the small blood vessels leading to damage in any number of organs.	22673710
Compression, Acute inflammation, Cleaved	Altered Intercellular Communication	Internal compression of the cleft by the haptic of a normal sized IOL along with postoperative inflammation led to scarring and closure of the cleft.	22673716
Inflammation	Altered Intercellular Communication	Ten weeks after the last injection, cartilage matrix turnover and synovial inflammation were analyzed.	22674062
Inflammation	Altered Intercellular Communication	Synovial inflammation was present only after intraarticular injections with coagulating blood.	22674062
Inflammation, Small vessel vasculitis, Myalgia, CTCAE 5	Altered Intercellular Communication	Primary small vessel vasculitis of the skeletal muscle should be considered in patients presenting with myalgia and signs of systemic inflammation in the absence of other organ manifestations.	22674106
Airway structure, Sleep Apnea, Obstructive	Altered Intercellular Communication	Analysis of systemic and airway inflammation in obstructive sleep apnea.	22674397
Airway structure, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	The presence of both systemic and airway inflammation has been suggested in obstructive sleep apnea (OSA) by increased levels of inflammatory biomarkers in the circulation and respiratory specimens.	22674397
Airway structure, Osage language	Altered Intercellular Communication	We aimed to investigate the relationship between systemic and airway inflammation in OSA.	22674397
Airway structure, Morbid obesity, Osage language	Altered Intercellular Communication	Systemic and airway inflammation in OSA might be differently regulated by OSA itself and comorbid obesity, depending on the type of cytokine.	22674397
Inflammation, HIV-1 Infection Pathway	Altered Intercellular Communication	We also saw a gradual decline of the CD4+T cell count, widespread immune activation, up-regulation of inflammation marker and microbial translocation after HIV-1 infection.	22675567
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) is a disease characterized by inflammation of the nasal mucosa and paranasal sinuses.	22676062
Inflammation, Fungal Colonization	Altered Intercellular Communication	This inflammation may result in part from decreased epithelial barrier and innate immune responses, leading to frequent bacterial and fungal colonization.	22676062
Inflammation, Obesity	Altered Intercellular Communication	Increased MIF concentrations were associated with increased markers of inflammation and obesity.	22676646
Inflammation, Obesity	Altered Intercellular Communication	Taken together with other markers, this indicates the presence of low-grade inflammation in these young subjects, possibly representing a link between obesity and related co-morbidities.	22676646
Liver carcinoma	Altered Intercellular Communication	An inflammation-based prognostic index predicts survival advantage after transarterial chemoembolization in hepatocellular carcinoma.	22677364
Inflammation, Atherosclerosis	Altered Intercellular Communication	No sign of atherosclerosis or inflammation was detected.	22678132
Airway structure, Asthma, Respiratory Hypersensitivity, Obesity	Altered Intercellular Communication	Obesity is a risk factor for asthma in the general population, but the effect of obesity on airway hyperresponsiveness (AFHR) or airway inflammation in asthma is not clear.	22678356
Kidney Failure, Chronic	Altered Intercellular Communication	Low free triiodothyronine (fT3) has been associated with the presence of malnutrition-inflammation syndrome in patients with end-stage renal disease (ESRD) and decreased overall survival in ESRD.	22678525
Abscess of aortic root	Altered Intercellular Communication	After careful consideration, it is likely that what was thought to be an aortic root abscess was instead an area of perivalvular inflammation.	22678733
Inflammation	Altered Intercellular Communication	Perivascular inflammation may have an important role in the processes of vascular remodeling, all of which may ultimately lead to increased pulmonary artery pressure.	22679007
ARCN1 gene, Inflammation, Mast cell infiltration, Pulmonary Emphysema, Hyperreactivity	Altered Intercellular Communication	Hence, we investigated mast cell infiltration, along with overall inflammation, and their relation with hyperreactivity and emphysema type in COPD.	22679009
Inflammation, Pulmonary Emphysema, Alveolar wall	Altered Intercellular Communication	We studied lung function, emphysema type, mast cells, and overall inflammation in small airways and alveolar walls, along with alveolar wall thickening in 67 subjects undergoing lung resection (59 smokers, 8 nonsmokers).	22679009
ARCN1 gene, Inflammation	Altered Intercellular Communication	The pathological phenotypes of COPD CLE and PLE show important differences in their overall inflammation with a protagonism of mast cells, which are related to airway reactivity.	22679009
Inflammation, Inflammatory colitis	Altered Intercellular Communication	Colonoscopy demonstrated inflammation up to the splenic flexure and histology confirmed inflammatory colitis.	22679163
Inflammation, Cronkhite-Canada Syndrome, Edema	Altered Intercellular Communication	Biopsies showed cystic glandular dilatation, lamina propria oedema and chronic inflammation consistent with Cronkhite-Canada syndrome (CCS).	22679262
Inflammation, ciliary vesicle	Altered Intercellular Communication	Inflammation in early life may play a causal role in the adult association between short LTL and CV disease.	22679311
Inflammation	Altered Intercellular Communication	It is characterised by inflammation, increased deposition of submucosal collagen and formation of fibrotic bands in the oral and paraoral tissues, which increasingly limit mouth opening.	22679326
Inflammation, Coronary heart disease	Altered Intercellular Communication	[Effects of naoxintong capsule on the inflammation and prognosis in borderline lesion coronary heart disease patients].	22679718
Inflammation, Fibrosis Assessment, Diverticular Diseases	Altered Intercellular Communication	Inflammation may be detected in diverticular disease (DD), and fibrosis may also develop.	22680042
Weight Gain	Altered Intercellular Communication	Other important morbidities were persistent hormonal disturbances and weight gain.	22680243
Granuloma, Periodontitis, Inflammation	Altered Intercellular Communication	The presence of granuloma in apical periodontitis (AP) is linked with inflammation and the synthesis of metabolites of AA.	22682033
Immunologic Deficiency Syndromes, Qualitative abnormality of granulocyte, Cystic Fibrosis	Altered Intercellular Communication	Currently it is thought more likely that the following factors are involved: progressive increase in dilatation of small bronchi, delayed diagnosis, morphological abnormalities of the thorax, hormonal factors, immune deficiency, genetic neutrophil dysfunction, and even heterozygous forms of cystic fibrosis.	22682598
Inflammation, anatomical bulb	Altered Intercellular Communication	Slit-lamp examination performed 2 weeks later showed severe inflammation and areas of ulceration along all 4 lids and complete, bilateral sloughing of bulbar and palpebral conjunctivae, including the limbus.	22683916
Obstructive chronic pancreatitis, Inflammation, Primary	Altered Intercellular Communication	Stenosis of the pancreaticoenterostomy induces obstructive chronic pancreatitis, which occurs due to primary stenosis or obstruction of the main pancreatic duct and causes in inflammation of the distal pancreas.	22683982
Inflammation, Sleeplessness, Coronary heart disease	Altered Intercellular Communication	Our results do not support the hypothesis that inflammation, as reflected by elevated levels of hsCRP, is an important factor linking insomnia to coronary heart disease.	22685243
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Delayed neutrophil apoptosis may be an important factor in the persistent inflammation associated with chronic obstructive pulmonary disease (COPD).	22686245
Inflammation, Anemia, Kidney Diseases	Altered Intercellular Communication	Major causes of persistent or recurrent anemia at follow up were renal disease (62%) and chronic inflammation (35%).	22686591
Intraocular inflammation	Altered Intercellular Communication	Subjects who received bevacizumab were 12 times more likely to develop severe intraocular inflammation following each injection than were those who received ranibizumab (OR = 11.71; 95% CI 1.5-93).	22687306
Unspecified visual loss	Altered Intercellular Communication	The 1 case of acute intraocular inflammation following ranibizumab injection was mild and not associated with vision loss.	22687306
Pheochromocytoma, Mass of pancreas	Altered Intercellular Communication	Imaging revealed a pancreatic mass with biliary and pancreatic ductal dilatation and a hormonal assay led to the diagnosis of functional pheochromocytoma.	22687375
Inflammation, Atherosclerosis	Altered Intercellular Communication	Effect of rosuvastatin on ROCK activity, endothelial function, and inflammation in Asian patients with atherosclerosis.	22687786
Renal Insufficiency, Inflammation, Hematuria, CTCAE	Altered Intercellular Communication	When hematuria was first discovered in 2008, renal dysfunction [creatinine (Cr), 1.2 mg/dL], inflammation [C-reactive protein (CRP), 12 mg/dL] and high myeloperoxidase anti-neutrophil cytoplasmic antibodies (MPO-ANCA) levels [546 ELISA units (EU)] were observed.	22687795
Inflammation	Altered Intercellular Communication	Chronic inflammation and long-term changes in expression of cytokines and growth factors after GKS may have triggered this case.	22688073
Inflammation, Diabetic foot ulcer, Failure (biologic function)	Altered Intercellular Communication	We examined the role of vascular function and inflammation in the development and failure to heal diabetic foot ulcers (DFUs).	22688339
Inflammation, Failure (biologic function)	Altered Intercellular Communication	We conclude that increased inflammation, expression of MMP-9, PTP1B, and aberrant growth factor levels are the main factors associated with failure to heal DFUs.	22688339
Inflammation, Fracture, Traumatic injury	Altered Intercellular Communication	Quantification of surgical trauma: comparison of conventional and minimally invasive surgical techniques for pertrochanteric fracture surgery based on markers of inflammation (interleukins).	22688402
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Reduction of oxidative stress and inflammation by blunting daily acute glucose fluctuations in patients with type 2 diabetes: role of dipeptidyl peptidase-IV inhibition.	22688551
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	MAGE reduction is associated with reduction of oxidative stress and markers of systemic inflammation in type 2 diabetic patients.	22688551
Hepatic inflammation	Altered Intercellular Communication	We investigated whether reduced hepatic inflammation was associated with clinical benefit in 834 patients with a baseline and follow-up biopsy 1.5 years after randomization to peginterferon or observation.	22688849
MS gene, Inflammation, White matter lesions	Altered Intercellular Communication	In multiple sclerosis (MS), gray matter pathology is characterized by less pronounced inflammation when compared with white matter lesions.	22689449
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver biopsy showed macrovesicularsteatosis without fibrosis or inflammation.	22689598
Inflammation, Metabolic Syndrome X, Chronic Kidney Diseases	Altered Intercellular Communication	Low-grade inflammation, metabolic syndrome and the risk of chronic kidney disease: the 2005 Korean National Health and Nutrition Examination Survey.	22690094
Renal Insufficiency, Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Either chronic inflammation or metabolic syndrome (MetS) is associated with renal impairment.	22690094
Inflammation, Chronic Kidney Diseases, ETV3 wt Allele	Altered Intercellular Communication	Low-grade inflammation is significantly associated with CKD stage 3 or more in subjects with MetS but not in those without MetS.	22690094
Neurogenic Inflammation, Otitis Media with Effusion	Altered Intercellular Communication	The etiology of OME is multifactorial, and neurogenic inflammation may play a significant role.	22691066
Asthma, allergic inflammation	Altered Intercellular Communication	Airways allergic inflammation and L. reuterii treatment in asthmatic children.	22691248
allergic inflammation	Altered Intercellular Communication	Recently, it has been hypothesized that the oral administration of specific live probiotic strains may have therapeutic potential in the treatment of allergic inflammation.	22691248
Asthma, Bronchitis	Altered Intercellular Communication	In conclusion, these data showed that L. reuteri (108 CFU) was effective in reducing bronchial inflammation in asthmatic children.	22691248
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	The cholinergic and glutamatergic neurotransmission systems are known to be severely disrupted in Alzheimer's disease (AD).	22691495
Inflammation, Pilomatrixoma	Altered Intercellular Communication	Pilomatricoma is uncommon in adults and an unusual cause for marked FDG uptake, likely due to foreign body inflammation.	22691514
Inflammation	Altered Intercellular Communication	This translational study opens new avenue to investigate ocular surface disorders by focusing on chemokine-related inflammation and immune cell trafficking in the ocular conjunctival mucosa.	22692452
Immune System Diseases	Altered Intercellular Communication	Inappropriate expression of the chemokine CX3CL1 is reportedly known to act on inflammatory conditions in extraocular immune diseases.	22692452
Inflammation, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	Chronic inflammation promotes atherosclerosis in cardiovascular disease and is a major prognostic factor for patients undergoing percutaneous coronary intervention (PCI).	22693633
Inflammation	Altered Intercellular Communication	The results failed to support that an Er:YAG laser may be superior to conventional debridement in the treatment of smokers with recurring chronic inflammation.	22694321
Inflammation	Altered Intercellular Communication	This appears to be the first time that repeated Er-YAG laser instrumentation has been compared with mechanical instrumentation of periodontal sites with recurring chronic inflammation over a clinically relevant time period.	22694321
vascular inflammations, Diabetes Mellitus	Altered Intercellular Communication	These results suggest inhibition of Rho/ROCK signaling may have therapeutic potential in preventing diabetes associated vascular inflammation and atherogenesis.	22694757
Myocarditis	Altered Intercellular Communication	Both the non-IMID and IMID DCM patients demonstrated increased myocardial inflammation compared to controls: 12.5 +- 1.8 and 14.0 +- 3.2 CD45-positive inflammatory cells, respectively, versus 5.1 +- 0.7 for the controls (P < 0.05 for both).	22695157
Inflammation	Altered Intercellular Communication	Histology results from the liver and omentum revealed necrotising granulomatous inflammation suggestive of TB.	22696746
Hepatitis C, Chronic, Hepatitis	Altered Intercellular Communication	Extent of liver inflammation in predicting response to interferon a & Ribavirin in chronic hepatitis C patients: a cohort study.	22697612
Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Hepatitis C, Hepatitis	Altered Intercellular Communication	Liver inflammation due to HCV infection leads to fibrosis, which is an independent predictor of treatment response to interferon therapy in Chronic Hepatitis C (CHC) patients.	22697612
Hepatitis	Altered Intercellular Communication	ALT is a less invasive test than liver biopsy for measuring liver inflammation.	22697612
Hepatitis	Altered Intercellular Communication	Diagnostic accuracy of pretreatment ALT for liver inflammation grades was determined by computing Area Under the Receiver Operator Curve (AUROC).	22697612
Hepatitis	Altered Intercellular Communication	Among them, 103 had high and 569 had low grades of liver inflammation.	22697612
Inflammation	Altered Intercellular Communication	Mean age was 36.9 (SD 9.1) years, with patients with high grades being older than those with low grades inflammation (p = 0.03).	22697612
Fibrosis, Liver, Hepatitis	Altered Intercellular Communication	High grades of liver inflammation was associated with ETR (RR 1.17, 95% CI 1.12-1.18) adjusting for age, Total Leukocyte count (TLC) and pretreatment levels of ALT, irrespective of liver fibrosis.	22697612
Inflammation	Altered Intercellular Communication	AUROC of pretreatment ALT for males and females was moderately accurate for severe inflammation compared to minimal inflammation and less accurate for high grades compared to low grades.	22697612
Fibrosis Assessment, Hepatitis, Liver Cirrhosis	Altered Intercellular Communication	ETR in patients with higher grades of liver inflammation was 17% higher than those with lower grades irrespective of fibrosis and 9% higher for bridging fibrosis and cirrhosis.	22697612
Inflammation	Altered Intercellular Communication	Pretreatment ALT was moderately accurate for severe inflammation only on liver biopsy in both males and females.	22697612
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	The biosynthetic interface between the patient and the circuit can significantly alter inflammation, coagulation, pharmacokinetics and disposition of trace elements.	22697617
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	We obtained preliminary data on inflammation, coagulation, histology, pharmacokinetics and trace element disposition during ECLS.	22697617
methyldopa, Inflammation, Age related macular degeneration	Altered Intercellular Communication	Oxidative stress and inflammation are known to be associated with age-related macular degeneration (AMD).	22698681
Inflammation, Brain Injuries, physiopathological	Altered Intercellular Communication	Cerebrospinal fluid markers of brain injury, inflammation, and blood-brain barrier dysfunction in cardiac surgery.	22698770
Inflammation	Altered Intercellular Communication	Cerebral microembolization, inflammation, blood-brain barrier (BBB) dysfunction, and impaired cerebral oxygenation are considered among possible etiologies.	22698770
Inflammation, Trauma, Nervous System, physiopathological, cell injury	Altered Intercellular Communication	Cardiac surgery with cardiopulmonary bypass causes cerebral inflammation, glial cell injury, and BBB dysfunction without biochemical signs of neuronal damage.	22698770
Inflammation	Altered Intercellular Communication	Inflammation induced by chemotherapy may contribute to hippocampal changes that underlie these deficits.	22698992
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Experimental data suggested that MRP8/14 is important in the initiation and progression of inflammation and cardiovascular diseases.	22699162
Inflammation, Skin Angiosarcoma	Altered Intercellular Communication	Angiosarcoma of the scalp diagnosed by the presence of neck inflammation: a case report.	22699262
Inflammation, Skin Angiosarcoma	Altered Intercellular Communication	This article describes a rare case of angiosarcoma of the scalp, presenting as neck inflammation.	22699262
Pain Distress Question, Swelling, Neck Pain	Altered Intercellular Communication	Although patients generally describe pain and swelling at the primary lesion site, this patient complained only of painful neck inflammation, without any indication of pain or swelling of the scalp.	22699262
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Blood Glucose	Altered Intercellular Communication	This novel IL-1b-neutralizing antibody improved glycemia, possibly via restored insulin production and action, and reduced inflammation in patients with type 2 diabetes.	22699287
Inflammation, Abnormality of the vasculature, Vascular Diseases	Altered Intercellular Communication	However, these vascular abnormalities are related to signs of systemic low grade inflammation, suggesting a common pathophysiological mechanism apparently present also in other vascular diseases but yet to be elucidated.	22699414
Hypotension, CTCAE, Inflammation	Altered Intercellular Communication	To evaluate the balance between arginine-vasopressin (AVP) and apelin during hemodialysis and its role in hypotension onset and in the inflammation status.	22699819
Inflammation, Tuberculosis	Altered Intercellular Communication	TEVAR was performed considering: (1) no preoperative ongoing inflammation, (2) no evidence of tuberculosis recurrence, and (3) risk factors, such as pulmonary impairments and high age.	22700454
Pneumonitis, alpha 1-Antitrypsin Deficiency	Altered Intercellular Communication	The variability of pulmonary inflammation in patients with a(1)-antitrypsin deficiency (A1ATD) is unknown.	22700846
Inflammation, Uveitis	Altered Intercellular Communication	Examination revealed perilimbal injection and anterior chamber inflammation in the left eye consistent with an anterior uveitis.	22701003
Hepatitis A, Inflammation	Altered Intercellular Communication	The rationale for seeking increased PA formation in chronic viral hepatitis is based on the involvement of activated macrophages in chronic viral hepatitis-associated inflammation.	22701277
Carcinogenic Chlorinated Hydrocarbon, Inflammation, Hepatitis C, Diabetes Mellitus	Altered Intercellular Communication	We assessed PA and high-sensitivity C-reactive protein (hsCRP) as a marker of inflammation in 51 patients with chronic hepatitis C infection (CHC), both with and without diabetes and 40 controls.	22701277
ARCN1 gene, Inflammation, Tissue injury	Altered Intercellular Communication	Systemic biomarkers of neutrophilic inflammation, tissue injury and repair in COPD patients with differing levels of disease severity.	22701684
Inflammation, Metabolic Diseases, Psoriasis	Altered Intercellular Communication	Both psoriasis and metabolic disorders are associated with systemic inflammation.	22702656
Immediate hypersensitivity, Data types - Address	Altered Intercellular Communication	IgE-mediated allergic inflammation may play an important role in the pathobiology of elderly AD, similar to other age groups of AD.	22702954
Idiopathic Inflammatory Myopathies, Paresis, Autoimmune reaction, Myositis	Altered Intercellular Communication	Idiopathic inflammatory myopathies (IIMs) are a rare group of autoimmune syndromes characterized by chronic muscle inflammation and muscle weakness with no known cause.	22703603
Inflammation	Altered Intercellular Communication	Endovascular repair for IAAA results in successful management with improvement of periaortic inflammation.	22703973
Inflammation, Pseudotumor, Necrosis	Altered Intercellular Communication	The resected mass consisted of necrotic tissue infiltrating inflammation cells, so it was diagnosed as pseudotumor.	22704029
Inflammation, vascular associated smooth muscle cell apoptotic process	Altered Intercellular Communication	Histologically AAAs are characterized by inflammation, vascular smooth muscle cell apoptosis, and extracellular matrix degradation.	22704053
Inflammation, Atherosclerosis	Altered Intercellular Communication	Stamp2 controls macrophage inflammation through nicotinamide adenine dinucleotide phosphate homeostasis and protects against atherosclerosis.	22704678
Inflammation	Altered Intercellular Communication	The six-transmembrane protein Stamp2 plays an important role in metabolically triggered inflammation and insulin action.	22704678
Diabetic Nephropathy, Inflammation	Altered Intercellular Communication	Chronic inflammation has emerged as being a key pathophysiology in the early stages of diabetic nephropathy.	22705282
Inflammation	Altered Intercellular Communication	YKL-40 has been established as an inflammatory marker in chronic inflammation.	22705282
Arterial Stiffness, Inflammation, Hypoxemia	Altered Intercellular Communication	If so, we examined the exaggeration of nocturnal hypoxemia and its related inflammation are related to this augmentation of increased arterial stiffness.	22705293
ARCN1 gene, Inflammation, Osage language, Hypoxemia, Arterial Stiffness	Altered Intercellular Communication	Thus, the overlap of COPD in patients with OSA augments increase in arterial stiffness without the exaggeration of nocturnal hypoxemia and inflammation.	22705293
Inflammation, Disease	Altered Intercellular Communication	Matrix metalloproteinase 9 (MMP-9) and the endogenous inhibitor to MMP-9, tissue inhibitor of metalloproteinase 1 (TIMP-1), have important roles in tissue remodelling and are implicated in a number of diseases related to inflammation.	22706255
Inflammation	Altered Intercellular Communication	Lipids which accumulate in the liver can stimulate inflammation, and the fatty acid derivatives, hydroxyeicosatetraenoic acids (HETEs) and hydroxyoctadecadienoic acids (HODEs), may play an important role in this process.	22706383
Inflammation, Diverticulitis	Altered Intercellular Communication	In most cases of diverticulitis, inflammation is mild, and the only treatment required is a clear liquid diet and antibiotics.	22706731
Nonalcoholic Steatohepatitis, Inflammation, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Fatty Liver Disease	Altered Intercellular Communication	An algorithm for segregating lesions into normal liver, NAFLD, or nonalcoholic steatohepatitis (NASH) was built based on semiquantitative evaluation of steatosis, hepatocellular ballooning, and lobular inflammation.	22707395
Inflammation, Fatty Liver Disease	Altered Intercellular Communication	The activity score (ballooning + lobular inflammation) enabled discriminating NASH because all patients with NASH had A >= 2, whereas no patients with A < 2 had NASH.	22707395
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Cachexia	Altered Intercellular Communication	Systemic inflammation may contribute to cachexia in patients with chronic obstructive pulmonary disease (COPD).	22708547
ARCN1 gene, Inflammation, Cachexia, TNF protein, human	Altered Intercellular Communication	This study does not support the hypothesis that systemic inflammation is the cause of accelerated loss of fat free mass in COPD patients, but suggests a role for TNF-a in already cachectic COPD patients.	22708547
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Arterial hypertension is characterised by increased oxidative stress and inflammation, which are associated with further cardiovascular risk.	22708640
Inflammation, Cytomegalovirus Infections	Altered Intercellular Communication	The age-related increase in low-grade systemic inflammation (Inflammaging) is not driven by cytomegalovirus infection.	22708923
Inflammation	Altered Intercellular Communication	Aging is accompanied by the development of low-grade systemic inflammation, termed 'inflammaging', characterized by raised serum C-reactive protein (CRP) and pro-inflammatory cytokines.	22708923
Presenile dementia, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	Importantly, inflammaging is implicated in the pathogenesis of several of the major age-related diseases including cardiovascular disease, type 2 diabetes, and dementia and is associated with increased mortality.	22708923
Inflammation, Cytomegalovirus Infections	Altered Intercellular Communication	The age-related increase in low-grade systemic inflammation (Inflammaging) is not driven by cytomegalovirus infection.	22708923
Inflammation	Altered Intercellular Communication	Aging is accompanied by the development of low-grade systemic inflammation, termed 'inflammaging', characterized by raised serum C-reactive protein (CRP) and pro-inflammatory cytokines.	22708923
Cytomegalovirus Infections, Inflammation	Altered Intercellular Communication	We conclude that CMV infection is not a primary causative factor in the age-related increase in systemic inflammation.	22708923
Inflammation	Altered Intercellular Communication	Chronic inflammation in older individuals is thought to contribute to inflammatory, age-related diseases.	22708967
Rosacea	Altered Intercellular Communication	Rosacea is a chronic inflammatory condition that affects the skin of the face and the eyes.	22709541
Inflammation, Neoplasms	Altered Intercellular Communication	CD8(+) T cells that produce interleukin (IL)-17 (Tc17 cells) promote inflammation and have been identified in tumors.	22710190
Inflammation, Data types - Address	Altered Intercellular Communication	The antioxidant vitamin complex was effective in reducing oxidative stress in PBMNC of AD patients by lowering ROS production, improving cellular antioxidant capacities and modifying cytokine induced inflammation.	22710805
Inflammation, Neoplasms	Altered Intercellular Communication	Focal inflammation around the tumor was observed at the exposed facial nerve.	22711394
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Osteopontin promotes inflammation in patients with acute coronary syndrome through its activity on IL-17 producing cells.	22711477
Acute Coronary Syndrome, Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Here we confirm the existence of a critical imbalance in the ratio of Th17 to Treg-cell populations in peripheral CD4(+) T cells from patients with acute coronary syndrome (ACS), which favors inflammation.	22711477
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	To our knowledge and beyond the disease context of ACS, this study constitutes the first demonstration of a critical role for OPN in the positive regulation of inflammation through increased IL-17 production by CD4(+) CD45RA(-) FOXP3(lo) cells.	22711477
Inflammation, Observation Method - Coagulation, Poor fine motor coordination	Altered Intercellular Communication	Inflammation, coagulation and risk of locomotor disability in elderly women: findings from the British Women's Heart and Health Study.	22711587
Inflammation, Observation Method - Coagulation, Poor fine motor coordination	Altered Intercellular Communication	This study investigated associations between chronic inflammation and coagulation and incident locomotor disability using prospective data from the British Women's Heart and Health Study.	22711587
Inflammation, Observation Method - Coagulation, Poor fine motor coordination	Altered Intercellular Communication	These results support the role of inflammation and coagulation in the development of locomotor disability in elderly women irrespective of their lifestyle factors and underlying age-related chronic diseases.	22711587
Renal Insufficiency, Inflammation, Pyelonephritis, Hydronephrosis	Altered Intercellular Communication	Bacterial inflammation was dominated symptom at the children with primary bacterial pyelonephritis, whereas children with hydronephrosis had low-grade clinical changes and significant renal functional impairment.	22712303
Inflammation, Dysplasia	Altered Intercellular Communication	The hystologic picture depends on lateralization of lesions: dysplasia of muscle layers is on the left side, mucous inflammation--on the right.	22712303
Sinusitis	Altered Intercellular Communication	Maxillary sinus inflammation, when untreated or incorrectly treated, may extend locoregionally, the remaining paranasal sinuses being the first affected anatomical structures.	22712359
helium, Inflammation	Altered Intercellular Communication	Laboratory indexes were obtained at the 30th, 60th, 90th days after gastric perfusion, which including state of mind, activity, fur, weight, joint swelling, largely image, hemorheology, inflammation and HE pathological appearance.	22712380
Degenerative polyarthritis, Inflammation, Cartilage injury	Altered Intercellular Communication	Knee osteoarthritis mainly show synovial inflammation at the early stage, inflammation at early stage is more severe than late; invigorating kidney and activating blood decoction can inhibit the knee cartilage injury, improve blood circulation and prevent local inflammatory reaction.	22712380
Toxic effect	Altered Intercellular Communication	Hyaluronidase toxicity: a possible cause of postoperative periorbital inflammation.	22712486
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	Periorbital inflammation following regional anaesthesia is commonly attributed to hyaluronidase allergy.	22712486
Cataract, Hypersensitivity, Toxic effect	Altered Intercellular Communication	Hyaluronidase toxicity, potentially related to concentration of hyaluronidase, may be a cause of postoperative periorbital inflammation after cataract surgery, rather than hypersensitivity.	22712486
Hypertension, CTCAE, Nephritis	Altered Intercellular Communication	Renal inflammation and oxidative stress are constantly present in experimental hypertension.	22713485
Stomach Carcinoma	Altered Intercellular Communication	Prognostic importance of the inflammation-based Glasgow prognostic score in patients with gastric cancer.	22713657
Neoplasms	Altered Intercellular Communication	The inflammation-based Glasgow prognostic score (GPS) has been shown to be a prognostic factor for a variety of tumours.	22713657
Inflammation, Carcinogenesis	Altered Intercellular Communication	A tissue microarray containing 115 core biopsies was constructed and stained for proteins involved in carcinogenesis, angiogenesis, inflammation, and cell-to-cell contact.	22715107
Inflammation, Carcinoma	Altered Intercellular Communication	We have demonstrated for the first time that proteins related to angiogenesis, inflammation, and cell proliferation are overexpressed in sebaceous gland carcinomas.	22715107
Inflammation, HIV Infections	Altered Intercellular Communication	Inflammation is a key feature of HIV infection and is correlated with long-term negative cardiovascular outcomes.	22715361
Limbic Encephalitis, Inflammation	Altered Intercellular Communication	In addition to temporal lobe involvement on the brain MRI and CSF inflammation, we propose EEG abnormalities as an additional diagnostic criterion for limbic encephalitis.	22715483
Low Vision, Orbital Pseudotumor	Altered Intercellular Communication	Despite an early response to treatment with intravenous amikacin, reactivation of left orbital inflammation led to eventual loss of vision.	22715939
Inflammatory abnormality of the eye	Altered Intercellular Communication	Regular ocular examinations revealed a mild to moderate transient ocular inflammation that resolved within 1 month of dosing in both species.	22716662
Inflammation, Dyslipidemias, Depression, CTCAE, Obesity, Anxiety Disorders	Altered Intercellular Communication	Increased dyslipidemia and (abdominal) obesity risk in patients with more severe anxiety disorders and depression may be partly explained by chronic low-grade inflammation and smoking.	22717171
Inflammation	Altered Intercellular Communication	Perioperative surgical outcomes, analgesic medication, and inflammation parameters were recorded.	22717549
Influenza-like illness, Heart failure, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Myocarditis is defined as acute inflammation of the myocardium, usually following a non-specific flu-like illness, and encompasses a wide range of clinical presentations ranging from mild or subclinical disease to heart failure.	22718060
Hypocomplementemia, Interstitial inflammation	Altered Intercellular Communication	Immunological tests revealed hypocomplementemia, and the renal biopsy specimen showed diffuse interstitial inflammation.	22718459
Hypercholesterolemia, Inflammation	Altered Intercellular Communication	There is a relationship among hypercholesterolemia, oxidative stress and inflammation in the atherogenesis.	22721254
Lipemia - observation, Inflammation, physiopathological	Altered Intercellular Communication	Postprandial lipemia has been associated with inflammation, oxidative stress and vascular dysfunction.	22721722
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	After adjustment for age and sex, RH-PAT was linked to condition, FFMI, myocardial infarction history, FEV(1), PaCO(2), heart rate, bicarbonates, inflammation and walking distance (p<0.10).	22721944
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Higher FFMI was associated with higher inflammation, oxidative stress and endothelial dysfunction.	22721944
Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Vascular Diseases	Altered Intercellular Communication	NO-deficient states are characterized by cell senescence, oxidative stress, inflammation, endothelial dysfunction, vascular disease, insulin resistance and type 2 diabetes mellitus.	22722323
Conjunctivitis	Altered Intercellular Communication	At diagnosis, 64/163 (39%) eyes had moderate/severe conjunctival inflammation, and 102/164 (62%) had symblepharon formation.	22722485
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Peripheral Neuropathy, Osage language	Altered Intercellular Communication	Because OSA is associated with inflammation and oxidative stress, we hypothesized that OSA is associated with peripheral neuropathy in type 2 diabetes.	22723291
Refractory anemias, Inflammation, Rheumatoid Arthritis, Tenosynovitis	Altered Intercellular Communication	To identify bilateral hand and wrist findings of synovial inflammation associated with progression to rheumatoid arthritis (RA) in very-early-RA cohort (VERA) (duration, <3 months) and early-RA cohort (ERA) (duration, <12 but >3 months), to test tenosynovitis as a magnetic resonance (MR) imaging additional parameter for improving diagnostic accuracy of the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) RA classification criteria, and to evaluate the symmetry of joint and tendon involvement.	22723498
Sialadenitis, Inflammation, Carcinoma, Structure of submaxillary duct, Malignant Neoplasms	Altered Intercellular Communication	Bilateral carcinoma in situ of Wharton's duct after chronic obstructive sialadenitis: inflammation as the cause of malignancy?	22724274
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	We discuss etiologic factors and chronic inflammation as a possible cause of malignancy.	22724274
Inflammation, Gastrointestinal mucositis	Altered Intercellular Communication	Oral mucositis is a serious complication of chemotherapy that results in painful debilitating inflammation, necessitating the administration of analgesics.	22724877
Inflammation, Fibrosis Assessment, Fatty degeneration, Portal inflammation	Altered Intercellular Communication	We took specimens from three different parts of each liver and recorded the degrees of steatosis, hepatocyte ballooning, lobular inflammation, portal inflammation, and fibrosis.	22724878
Inflammation	Altered Intercellular Communication	Fibrosis[intra-class correlation (ICC) = 0.87], lobular inflammation (kappa = 0.83), and portal inflammation (kappa = 0.83)were fairly uniformly distributed in the damaged liver.	22724878
Sepsis, Inflammation	Altered Intercellular Communication	Plasma leukocyte cell-derived chemotaxin 2 is associated with the severity of systemic inflammation in patients with sepsis.	22725643
Inflammatory disorder	Altered Intercellular Communication	The aim of the present study was to determine the correlations between leukocyte cell-derived chemotaxin 2 (LECT2) and inflammation-related variables in human inflammatory disease.	22725643
Sepsis, Inflammation	Altered Intercellular Communication	Thus, the LECT2 concentration correlates with the severity of systemic inflammation in patients with sepsis.	22725643
Hyperglycemia, Impaired T cell function, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Evaluate anti-interleukin-1b (IL-1b) antibody, canakinumab, in patients with type 2 diabetes and impaired glucose tolerance (IGT) in whom hyperglycaemia may trigger IL-1b-associated inflammation leading to suppressed insulin secretion and b-cell dysfunction.	22726220
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Comparative analysis of inflamed and non-inflamed colon biopsies reveals strong proteomic inflammation profile in patients with ulcerative colitis.	22726388
Inflammation, Bulla, Autoimmune Disorder, CTCAE	Altered Intercellular Communication	Mucous membrane pemphigoid (MMP) is an autoimmune blistering disorder characterized by inflammation, blistering, and scarring and predominantly occurring at mucous membranes.	22727107
Inflammation	Altered Intercellular Communication	Whereas with the PI no difference between the two groups was found (p = 0.9), the ACS-group showed significantly more signs of inflammation (GI) than the H-group (p = 0.045).	22727119
Inflammation, Tooth Loss, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Although, the state of oral health of the ACS-group differed only insignificantly from that of control, patients with ACS showed more signs of gingival inflammation and a higher loss of teeth.	22727119
Inflammation, Neuralgia, Leprosy	Altered Intercellular Communication	It can be nociceptive due to tissue inflammation occurring during episodes of immune mediated reactions, or neuropathic due to leprosy affecting the somatosensory system.	22727538
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Dietary energy density, inflammation and energy balance in palliative care cancer patients.	22727547
Inflammation	Altered Intercellular Communication	Thus, targeting systemic inflammation may be important in nutritional interventions in this patient group.	22727547
Collagenous Sprue, Inflammatory disease of mucous membrane, Villous atrophy	Altered Intercellular Communication	Intestinal biopsies showed both villous atrophy and variable degrees of mucosal inflammation in 15 patients, and marked subepithelial collagen deposition (collagenous sprue) in 7.	22728033
Inflammation, Acute myocardial infarction, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Activated inflammation is related to the incidence of atrial fibrillation in patients with acute myocardial infarction.	22728476
Atrial Fibrillation, Acute myocardial infarction, Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	The purpose of this study was to investigate the relationship between the new onset of atrial fibrillation (AF) and inflammation in the early phase of acute myocardial infarction (AMI).	22728476
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	Background Serial interaction between inflammation and the incidence of AF is not fully understood in the early phase of AMI.	22728476
Inflammation	Altered Intercellular Communication	MRI showed the inflammation in the sinus spread into the central nerve system.	22729220
Cholecystitis, Fibrosis Assessment, Inflammation, Inflammatory disorder	Altered Intercellular Communication	Xanthogranulomatous cholecystitis is an unusual inflammatory disease of the gallbladder characterised by severe proliferative fibrosis and the accumulation of lipid-laden macrophages in areas of destructive inflammation.	22729338
HD Term Type, Inflammation	Altered Intercellular Communication	Chronic inflammation is present in most HD patients.	22729528
Inflammation	Altered Intercellular Communication	Visual evoked potential (VEP) and multifocal electroretinogram (mfERG) in ocular syphilitic posterior segment inflammation.	22729668
Neurotransmitters, Movement Disorders, Neurologic Deficits, Impaired, Epilepsy	Altered Intercellular Communication	BH(4) deficiencies are a group of treatable pediatric neurotransmitter disorders that are characterized by motor dysfunction, mental retardation, impaired muscle tone, movement disorders and epileptic seizures.	22729819
Cholecystitis	Altered Intercellular Communication	In the present study we aimed to verify whether severe gallbladder inflammation would adversely affect the outcome of LCBDE.	22729830
Inflammation, Weight decreased, Malignant Head and Neck Neoplasm	Altered Intercellular Communication	Treatment of symptoms and systemic inflammation are important clinical targets to manage weight loss in patients with head and neck cancer, especially those treated with chemoirradiation.	22730077
Inflammation, Heart failure, Anemia	Altered Intercellular Communication	Inflammation and anaemia in a broad spectrum of patients with heart failure.	22730482
Inflammation, Anemia	Altered Intercellular Communication	Although inflammation is assumed to be an important cause of anaemia, the association between anaemia and inflammatory markers in patients with HF has not been well established.	22730482
Inflammation, Anemia	Altered Intercellular Communication	Anaemia is present in 40% of patients hospitalised for HF and is independently associated with inflammation.	22730482
Inflammation, Chronic Necrotizing Pulmonary Aspergillosis	Altered Intercellular Communication	Systemic biomarkers of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis.	22731696
2,3-Cyclic-Nucleotide Phosphodiesterases", Inflammation, Chronic Necrotizing Pulmonary Aspergillosis	Altered Intercellular Communication	The purpose of this study was to investigate mediators of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis (CNPA), a locally, destructive process of the lung due to invasion by Aspergillus species.	22731696
2,3-Cyclic-Nucleotide Phosphodiesterases", Inflammation, Thrombosis	Altered Intercellular Communication	Increased concentrations of circulating mediators of inflammation interleukin (IL)-6, IL-8, RANTES, TNF-a, ICAM-1 and mediators involved in endothelial activation and thrombosis (vWF, TF and PAI-1) were observed in patients with CNPA.	22731696
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	High-normal levels of liver enzymes, especially GGT, and systemic low-grade inflammation could be considered features of metabolic syndrome among children.	22731985
methyldopa, Inflammation	Altered Intercellular Communication	Oxidative damage and inflammation are related to the pathogenesis of age-related macular degeneration (AMD).	22732187
Primary malignant neoplasm	Altered Intercellular Communication	Prognostication in advanced cancer: a study examining an inflammation-based score.	22732417
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Biomarkers of systemic inflammation (C-reactive protein and albumin) combined in the modified Glasgow Prognostic Score (mGPS) have been used to assist prognostication in various cancer types.	22732417
Inflammation, Liver carcinoma	Altered Intercellular Communication	A novel and validated prognostic index in hepatocellular carcinoma: the inflammation based index (IBI).	22732513
Inflammation, FAM126A gene	Altered Intercellular Communication	As chronic inflammation is associated with the pathogenesis of HCC, we explored the prognostic impact of a panel of inflammatory based scores, including the modified Glasgow Prognostic Score (mGPS), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), in independent cohorts.	22732513
Inflammation, FAM126A gene	Altered Intercellular Communication	Systemic inflammation as measured by the mGPS, independently predicts overall survival in HCC.	22732513
Inflammation, FAM126A gene	Altered Intercellular Communication	These data enable formulation of a new prognostic system, the inflammation based index in HCC (IBI).	22732513
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	Obesity is associated with lowgrade systemic inflammation which has been linked to the increased risk of cardiovascular disease and Type 2 diabetes in obese patients.	22733212
Refractory anemias, Inflammation, Rheumatoid Arthritis, Destruction (action)	Altered Intercellular Communication	Recent studies point to important roles for IL-17 and Th17 cells in sustaining chronic inflammation and articular destruction in rheumatoid arthritis (RA).	22733231
Inflammation, Primary malignant neoplasm, Fatigue	Altered Intercellular Communication	Inflammation and fatigue dimensions in advanced cancer patients and cancer survivors: an explorative study.	22736424
Inflammation, Fatigue	Altered Intercellular Communication	Inflammation may underlie cancer-related fatigue; however, there are no studies that assess the relation between fatigue and cytokines in patients with advanced disease versus patients without disease activity.	22736424
Inflammation, Primary malignant neoplasm, Fatigue	Altered Intercellular Communication	In advanced cancer, inflammation seems to be associated with physical fatigue, but not to mental fatigue.	22736424
Inflammation, Primary malignant neoplasm, Fatigue	Altered Intercellular Communication	In cancer survivors, there was no convincing evidence that inflammation plays a major role in fatigue.	22736424
Acute viral encephalitis, Inflammation	Altered Intercellular Communication	The patient was treated for acute viral encephalitis because of the presence of inflammation.	22736758
Inflammation, Dyslipidemias, Hypertension, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	Rates of diabetes, dyslipidaemia, hypertension and inflammation are high and increased with age and were associated with urbanization.	22738663
Inflammation	Altered Intercellular Communication	PAI-1 synthesis in adipose tissue due to acute systemic inflammation may be a link between inflammation and impaired endogenous fibrinolysis.	22740034
Vitreous inflammatory cells	Altered Intercellular Communication	Marked resolution of the vitreous inflammation was observed in both eyes, and the serum b-D-glucan level was reduced.	22740188
Inflammation	Altered Intercellular Communication	Interestingly, white matter microglia from donors with peripheral inflammation displayed elevated CD45 levels and increased size and granularity, but were still distinct from macrophages.	22740309
Inflammation, Juvenile rheumatoid arthritis	Altered Intercellular Communication	Do patients with juvenile idiopathic arthritis in clinical remission have evidence of persistent inflammation on 3T magnetic resonance imaging?	22740386
Synovitis, Inflammation, Tenosynovitis	Altered Intercellular Communication	Over one-half of the patients in clinical remission had MRI evidence of persistent inflammation, defined as the presence of synovitis, tenosynovitis, or BMLs.	22740386
Traumatic injury	Altered Intercellular Communication	Bruises/contusions, strains, inflammation/swelling, and sprains were the most common types of injuries that occurred during both competition and training.	22743236
Inflammation, DLST wt Allele, Fatigue	Altered Intercellular Communication	DLTs were observed (fatigue, n = 2 and paronychial inflammation, n = 1) in three of 13 patients evaluated for DLTs.	22743295
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is suggested to influence atherosclerosis, but could also increase PP.	22743685
Arterial Stiffness, Inflammation	Altered Intercellular Communication	This suggests that both estimated arterial stiffness and inflammation contribute through different pathways to risk of CVD.	22743685
Granuloma, Inflammation	Altered Intercellular Communication	Complications of tumorigenesis by a lacrimal silicone plug are rarely reported and most of them were cases of granuloma due to chronic inflammation.	22743697
Inflammation, Myasthenia Gravis, Thyroid associated opthalmopathies	Altered Intercellular Communication	Other causes were inflammation (n = 7, 16 %), myasthenia gravis (n = 5, 11 %), and thyroid ophthalmopathy (n = 1, 2 %).	22743791
Sepsis, Inflammation	Altered Intercellular Communication	Alterations of adiponectin in the course of inflammation and severe sepsis.	22744305
Inflammation, Ischemic stroke	Altered Intercellular Communication	Evidence is emerging that inflammation plays a key role in the pathophysiology of ischemic stroke (IS).	22744645
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	We investigated the relationship between circulating markers of inflammation with brain and body temperature after stroke.	22744672
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Systemic inflammation after stroke is associated with elevated temperature in normal brain and the body but not with later ischemic brain temperature.	22744672
Airway structure, Colonization, Bronchiectasis, Damage	Altered Intercellular Communication	The vicious cycle hypothesis of bronchiectasis argues that bacterial colonization leads to airway inflammation and progressive lung damage.	22744718
Inflammation	Altered Intercellular Communication	Short- and long-term antibiotic treatments were associated with reductions in bacterial load, airways, and systemic inflammation.	22744718
Inflammation, Bronchiectasis, Exacerbation	Altered Intercellular Communication	High airway bacterial loads in non-CF bronchiectasis are associated with airway and systemic inflammation and a greater risk of exacerbations.	22744718
Inflammation, Tissue injury	Altered Intercellular Communication	Forkhead box P3 regulatory T cells control inflammatory responses, but it remains unclear whether they inhibit brain death-initiated inflammation and tissue injury in deceased kidney donors.	22745276
Inflammation	Altered Intercellular Communication	This suggests that NK cells respond to factors different from those driving T cell activation, but which are associated with inflammation in HIV patients.	22745371
Virus Diseases, Exacerbation	Altered Intercellular Communication	Thus our study demonstrates that in patients with COPD exacerbations, viral infection is directly associated with higher systemic levels of cytokines central to the development of the antiviral response, which are also known to contribute to inflammation-mediated tissue damage.	22746693
Percutaneous transhepatic cholangiography, Interstitial inflammation, Glomerulitis Assessment, Interstitial Fibrosis Assessment, Peritubular Capillaritis Assessment, Tubular atrophy	Altered Intercellular Communication	Peritubular capillaritis was present in 49 (84%), transplant glomerulitis was seen in 47 BS (81%), interstitial fibrosis and tubular atrophy in 47 (81%) and the thickening of the peritubular capillary (PTC) basement membrane (PTCBM) in 44 (76%), and interstitial inflammation was present in 26 BS (45%).	22747474
Inflammation	Altered Intercellular Communication	These results suggest that LRP-1 undergoes complex functional regulation following systemic inflammation which may depend on cell type, subcellular location, and post-translational modifications.	22747709
Inflammation, Data types - Address	Altered Intercellular Communication	Our findings that systemic inflammation causes deficits in both Ab transport and bulk flow like those observed in AD indicate that inflammation could induce and promote the disease.	22747709
Inflammation, Neurogenic Inflammation	Altered Intercellular Communication	However, there is no experimental evidence for a causal link between systemic inflammation or neuroinflammation and the onset of the disease.	22747753
Mesenteric Panniculitis, Fibrosis Assessment, Inflammation, Necrosis	Altered Intercellular Communication	Mesenteric panniculitis is a non-specific inflammation of the mesenteric adipose tissue, with varying degrees of fibrosis and fat necrosis.	22748362
Crohn Disease, Ulcerative Colitis	Altered Intercellular Communication	Several studies identified the presence of Epstein-Barr virus-infected B cells in the lesions of Crohn disease and ulcerative colitis suggesting that colon mucosa with chronic inflammation could be a potential site of Epstein-Barr virus replication.	22748471
Inflammation, Appendicitis, CTCAE, chronic diverticulitis	Altered Intercellular Communication	This density was similar to that observed in chronic diverticulitis but higher when compared with appendicitis, suggesting that chronic rather than acute inflammation facilitates the recruitment of Epstein-Barr virus-infected cells in diseased tissues.	22748471
Diabetes with coma (disorder), Inflammation	Altered Intercellular Communication	Expression of angiotensin-converting enzyme 2 and its end product angiotensin 1-7 is increased in diabetic atheroma: implications for inflammation and neovascularization.	22749485
Refractory anemias, Inflammation	Altered Intercellular Communication	PET/CT detection of inflammation in the ischial tuberosities, greater trochanters, and spinous processes discriminated between PMR and RA, but not between SpA and PMR.	22749663
Inflammation, Paresthesia, Nerve injury, Peri-Implantitis	Altered Intercellular Communication	For patients who experience transient paresthesia and recovery owing to nerve damage caused by the placement of an implant in the mandibular molar or premolar area, or in patients in whom the implant is close to the inferior alveolar nerve canal or the mental nerve, the spread of inflammation caused by peri-implantitis can induce paresthesia.	22749709
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	Methylation-dependent activation of CDX1 through NF-kB: a link from inflammation to intestinal metaplasia in the human stomach.	22749770
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Thrombin-activatable fibrinolysis inhibitor (TAFI), a procarboxypeptidase in plasma, plays a dual role in regulating both coagulation and inflammation.	22749979
Traumatic injury	Altered Intercellular Communication	This pilot study shows that TAFI levels are inversely correlated with inflammation-associated development of complications after major trauma.	22749979
palladium, Inflammation	Altered Intercellular Communication	Inflammation has been implicated in PD, and alpha-synuclein can initiate microglial activation; however, the kinetics and distribution of inflammatory responses to alpha-synuclein overexpression in vivo are not well understood.	22750327
Inflammation, Sarcopenia	Altered Intercellular Communication	Sarcopenia was positively associated with mobility impairment and inflammation and negatively with BMI.	22750356
Refractory anemias, Inflammation	Altered Intercellular Communication	The volume of inflammation was significantly higher in RA than in PsA for all the extensor compartments except the second, and in the joint synovial membrane.	22751591
PROS1 gene, Inflammation	Altered Intercellular Communication	The DCE-MRI indicators of the degree of inflammation were higher for PsA in the joint synovial membrane (p = 0.002 and p < 0.001, respectively).	22751591
Inflammation	Altered Intercellular Communication	There was a significant correlation between volume of inflammation but not its degree and 28-joint Disease Activity Score at the level of the wrist joint (r = 0.6; p = 0.01).	22751591
Inflammation, Sheehan Syndrome, pituitary dysfunction	Altered Intercellular Communication	High CD3 (+) DR (+) expression that correlates with the duration of illness in Sheehan's patients is suggestive of an ongoing inflammation accompanying the slow progression of pituitary dysfunction in Sheehan's syndrome.	22752347
Orbital Pseudotumor, Thyroid associated opthalmopathies	Altered Intercellular Communication	Our results suggest that the increased concentrations of CXCL9 (and CXCL10), at least in part, reflect the activity of orbital inflammation and therefore these chemokines could serve as a guideline in therapeutic decision-making in patients with Graves' orbitopathy.	22752955
Inflammation, Non-alcoholic Fatty Liver Disease, Fatty degeneration, Fatty Liver Disease	Altered Intercellular Communication	In NASH patients, VDR expression on cholangiocytes was inversely correlated with steatosis severity (P < 0.02), lobular inflammation (P < 0.01), and nonalcoholic fatty liver disease score (P < 0.03).	22753133
Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	In CHC subjects, fibrosis stage was associated with low hepatic CYP27A1 expression, whereas portal inflammation was significantly higher in patients with VDR-negative inflammatory cells (P < 0.009) and low VDR expression in hepatocytes (P < 0.03).	22753133
vascular inflammations	Altered Intercellular Communication	Epigallocatechin gallate reduces vascular inflammation in db/db mice possibly through an NF-kB-mediated mechanism.	22753231
vascular inflammations, Atherosclerosis, Diabetes Mellitus	Altered Intercellular Communication	Hyperglycemia-induced vascular inflammation resulting in the adhesion of monocytes to endothelium is a key event in the pathogenesis of atherosclerosis in diabetes.	22753231
vascular inflammations, Diabetes Mellitus	Altered Intercellular Communication	We investigated whether epigallocatechin gallate (EGCG), a major catechin found in green tea, reduces vascular inflammation in diabetes.	22753231
vascular inflammations, Diabetes Mellitus	Altered Intercellular Communication	EGCG may have a direct protective effect against vascular inflammation in diabetes.	22753231
Central hypothyroidism, Hypogonadism, Hyperprolactinemia	Altered Intercellular Communication	The most common hormonal features were gonadotropin deficiency (n=21), TSH deficiency (n=15) and hyperprolactinemia (n=12).	22753675
Inflammation, Hyperparathyroidism, Primary, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Primary hyperparathyroidism (PHPT) has been associated with low-grade inflammation and elevated risk of cardiovascular disease (CVD).	22757621
Arthritis, Headache	Altered Intercellular Communication	Arthritis, other inflammation-related musculoskeletal conditions, and headaches were associated with increased BPH risk (hazard ratio (HR) = 1.77 (95% confidence interval (CI): 1.37, 2.29), HR = 1.57 (95% CI: 1.14, 2.17), and HR = 1.40 (95% CI: 1.09, 1.80), respectively).	22759721
Hepatitis	Altered Intercellular Communication	We also found a positive correlation between the level of ferritin and liver inflammation during treatment (p<0.01).	22760008
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Although Th22 and Th17 cells have been reported to play critical roles during autoimmunity and inflammation, information on their role in cancer-immunity is limited.	22760549
Inflammation, Fibrosis Assessment, Edema, Lacrimal Duct Obstruction	Altered Intercellular Communication	Radioactive iodine uptake by nasolacrimal duct mucosa with subsequent inflammation, edema and fibrosis seems to have a relationship to lacrimal duct obstruction.	22760799
Vitritis, Vitreous opacities, Acute inflammation, Uveitis	Altered Intercellular Communication	25-gauge vitrectomy has proven its efficacy on cleansing vitreous opacities and improving visual acuity on patients with residual vitritis secondary to uveitis with minimal postoperative inflammation and complications.	22760801
Inflammation, Adenoma, Adenomatous Polyps	Altered Intercellular Communication	An initial exploration of a possible association of 5q loss with inflammation indicated that tumor-infiltrating lymphocytes were more abundant in the stroma of flat adenomas compared with that of polypoid adenomas.	22761468
Inflammation, Adenoma	Altered Intercellular Communication	Alterations more specific to flat adenomas, in particular 5q loss, may be associated with inflammation.	22761468
Inflammation	Altered Intercellular Communication	Eradicating HP reduces gastric inflammation, but does not eliminate it.	22761739
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	We speculate that this persistent inflammation might contribute to gastric mucosal pathology, for example, persistent increased gastric cancer risk despite eradication of HP.	22761739
Inflammation, Sepsis, Autoimmune Diseases, Communicable Diseases, Acute Coronary Syndrome, Rheumatoid Arthritis, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	The myeloperoxidase (MPO) content of circulating neutrophils was determined by flow cytometry in 330 subjects: 69 consecutive patients with acute coronary syndromes (ACS), 69 with chronic stable angina (CSA), 50 with inflammation due to either non-infectious (acute bone fracture), infectious (sepsis) or autoimmune diseases (small and large vessel systemic vasculitis, rheumatoid arthritis).	22761804
granulomatous uveitis, Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	Ocular inflammation was bilateral in 16 patients (69,6%), typical aspects of granulomatous uveitis were found in only 16 eyes over 39 (41%), posterior uveitis was found in 18 eyes (46.2%), with an averaged visual acuity of 5/10.	22763184
Inflammatory abnormality of the eye	Altered Intercellular Communication	The visual prognosis was good, with visual acuity greater than 6/10 in 96% of the cases if the ocular inflammation spared retina and choroid.	22763184
Intraocular inflammation, Sarcoidosis	Altered Intercellular Communication	Sarcoidosis may be revealed by an intraocular inflammation, with typical patterns in only 43% of the cases.	22763184
Inflammation, Overweight, physiopathological, Cardiovascular Diseases	Altered Intercellular Communication	Air pollution and autonomic and vascular dysfunction in patients with cardiovascular disease: interactions of systemic inflammation, overweight, and gender.	22763390
Inflammation, Overweight, physiopathological, Cardiovascular Diseases	Altered Intercellular Communication	The authors conclude that autonomic and vascular dysfunction may be one of the mechanisms through which air pollution exposure can increase cardiovascular disease risk, especially among persons with systemic inflammation and overweight.	22763390
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	C-reactive protein (CRP), an acute phase reactant and marker of inflammation, has been shown to be associated with CRP genetic variants and incident hypertension, but it is unclear whether this link is causal.	22763479
Inflammation	Altered Intercellular Communication	Chronic, low-grade inflammation involves general production of pro-inflammatory cytokines and inflammatory markers and is a typical feature of aging.	22763966
Sarcoidosis, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Patient underwent posterior fossa craniotomy with biopsy of left cerebellar lesion which revealed non-caseating chronic granulomatous inflammation, consistent with sarcoidosis.	22764471
hearing impairment, Inflammation, Perforation (observation), Otitis Media with Effusion	Altered Intercellular Communication	Secretory otitis media (SOM) is a chronic, nonpurulent inflammation of the middle ear, characterized by a long-term presence of liquids of different density in the middle ear for at least three consecutive months, different degrees of hearing loss and the absence of perforation of the eardrum.	22764543
Granuloma, Inflammation	Altered Intercellular Communication	A biopsy showed well formed granulomas, mixed inflammation with a predominance of neutrophils, and acid-fast bacilli.	22764735
Inflammation, Tumor necrosis	Altered Intercellular Communication	Inflammation, and especially tumour necrosis factor alpha (TNFa), has been associated with IR, and the administration of anti-TNFa agents is suggested to improve insulin sensitivity.	22765047
Endometriosis	Altered Intercellular Communication	Cutaneous deciduosis represents a rare manifestation of cutaneous endometriosis in which typical endometrial glands and stroma are morphologically and physiologically transformed under hormonal influence.	22765523
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	[Characteristics of stable chronic obstructive pulmonary disease related to systemic inflammation].	22766062
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by a systemic inflammation.	22766062
Myelofibrosis, Inflammation	Altered Intercellular Communication	In all specimens' area of bone, osteoid and remaining tissue were histomorphometrically determined and presence of cement particles, bone marrow fibrosis and signs of inflammation were recorded.	22766263
Inflammation, physiopathological, Thin-cap fibroatheroma	Altered Intercellular Communication	We hypothesized that microvascular dysfunction is associated with greater systemic inflammation and is a predictor of virtual histology-intravascular ultrasound (VH-IVUS)-defined coronary thin-cap fibroatheromas.	22766333
Inflammation, Brucellosis	Altered Intercellular Communication	Magnetic resonance imaging can detect thoracic inflammation due to familial Mediterranean fever.	22766764
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The IL28B genotype is predictive not only of SVR but also of the histologic diagnosis of posttransplant hepatitis C, with donor CC genotype favoring inflammation and fibrosis, and adverse outcomes during long-term follow-up.	22766768
Inflammation, Hepatitis, Necrosis	Altered Intercellular Communication	One key histological pattern in transplant liver pathology is spotty hepatocyte necrosis without significant lobular inflammation, which is typical of recurrent hepatitis C. Over the past years, we have observed several liver biopsies with a pattern of injury that mimicked the histological findings of early recurrent hepatitis C. This pattern consisted of increased lobular hepatocyte spotty necrosis without significant inflammation, but with the additional finding of numerous concurrent mitotic figures.	22766789
Inflammation	Altered Intercellular Communication	There was no significant difference between the study and the control groups in portal and lobular inflammation.	22766789
Inflammation, Liver Failure	Altered Intercellular Communication	In summary, our findings indicate that the histological pattern of concurrent increases in both hepatocyte mitosis and apoptosis in a post-transplant liver biopsy without significant lobular inflammation is strongly associated with hepatic arterial insufficiency and should prompt evaluation of the hepatic artery.	22766789
Inflammation, Sunburn	Altered Intercellular Communication	UV reactivation is an uncommon reaction characterized by recurrent inflammation in areas of prior sunburn or UV exposure following the administration of a triggering drug.	22768437
Communicable Diseases, Inflammation	Altered Intercellular Communication	Recently identified protein hepcidin synthesized in the liver, is thought to be a key regulator for iron homeostasis and is induced by infection and inflammation.	22768976
HD Term Type, Inflammation, Hepatitis C	Altered Intercellular Communication	We investigated the association of prohepcidin with inflammation and iron parameters in HD patients with and without chronic HCV infection.	22768976
Acute and chronic inflammation	Altered Intercellular Communication	The etiology is unclear, however it is considered to be secondary to chronic sinonasal inflammation.	22770260
Inflammation, MS gene	Altered Intercellular Communication	Correlations between serum uric acid level and disease activity, intrathecal inflammation reactivity in patients with multiple sclerosis.	22770406
Disability, Inflammation	Altered Intercellular Communication	In MS patients, UA levels might partly reflect the extent of disability and inflammation.	22770406
Inflammation	Altered Intercellular Communication	This may be related to differential contribution of neutrophil and lymphocyte to inflammation during AMI in diabetics vs. non-diabetics.	22771557
Renal Circulation, Inflammation, Injury of kidney	Altered Intercellular Communication	Renal vein blood from post-stenotic human kidneys has multiple markers reflecting active inflammation that portends kidney injury and reduced function.	22771675
Inflammation, Pain Distress Question, Fever, CTCAE, Brucellosis, Autosomal Recessive Disorder, Familial Mediterranean Fever	Altered Intercellular Communication	Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by recurrent attacks of fever and inflammation in the peritoneum, synovium, or pleura, accompanied by pain.	22771921
Inflammation	Altered Intercellular Communication	DNA-damage response associated with occupational exposure, age and chronic inflammation in workers in the automotive industry.	22772077
Ultraviolet B radiation, Sunburn, Carcinogenesis, Inflammation	Altered Intercellular Communication	Exposure to ultraviolet B (UVB) radiation from the sun can result in sunburn, premature aging and carcinogenesis, but the mechanism responsible for acute inflammation of the skin is not well understood.	22772463
Inflammation, Atherosclerosis, Cerebrovascular accident	Altered Intercellular Communication	Due to the fact that majority of carotid atheromatous plaques appear to be unstable or potentially unstable because of the inflammation and related mechanisms, the role of the inflammatory-immunologic component of atherosclerosis should be used in prophylaxis of stroke and the new therapeutic concepts worked out.	22773462
Inflammation	Altered Intercellular Communication	Bronchoalveolar lavage fluid from 66 was analyzed for the level of cellular inflammation, cytokines, and soluble leptin.	22773729
Inflammatory abnormality of the eye	Altered Intercellular Communication	No serious adverse event or ocular inflammation was reported in either group.	22775078
Gingivitis, Calculi, Dental Plaque	Altered Intercellular Communication	To analyze the diagnostic reliability of various partial-mouth recording systems (PMRS) for the simultaneous assessment of supragingival plaque, calculus, and gingival inflammation in a population of Portuguese adults.	22775296
Gingivitis, Calculi, Dental Plaque	Altered Intercellular Communication	A single examiner determined the levels of plaque, calculus, and gingival inflammation in 108 subjects using quantitative and dichotomous indices.	22775296
Degenerative polyarthritis, Rheumatoid Arthritis, Inflammation, Pain Distress Question	Altered Intercellular Communication	Rheumatoid arthritis and osteoarthritis are two diseases associated with severe pain, inflammation and limited activity.	22776021
Inflammation, Postpoliomyelitis Syndrome	Altered Intercellular Communication	Expression of inflammatory cytokines in cerebrospinal fluid (CSF) has led to the hypothesis of intrathecal chronic inflammation to explain the denervation observed in post-polio syndrome (PPS).	22776106
Inflammation, Calculus of cystic duct, anatomic, iatrogenic injury, Umbilical hernia	Altered Intercellular Communication	One hundred and ten patients (84.6%) underwent successful single-fulcrum LC, and 20 patients (15.4%) were converted to conventional surgery (n= 18) or required additional trocars (n= 2) during the procedure because of umbilical hernia (n= 3), severe inflammation or adhesion (n= 9), impacted cystic duct stone (n= 3), anatomical anomaly (n= 3) and iatrogenic injury (n= 2).	22776541
Inflammation, Overweight	Altered Intercellular Communication	Increased inflammation is present in obese compared with normal weight individuals, but inflammation characteristics of nonobese, overweight individuals are less clear.	22776879
Multiple Organ Failure, Cessation of life, Organ dysfunction syndrome, Shock, Hemorrhagic	Altered Intercellular Communication	Posttraumatic inflammation and excessive neutrophil activation cause multiple organ dysfunction syndrome (MODS), a major cause of death among hemorrhagic shock patients.	22777113
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	Traditional resuscitation strategies may exacerbate inflammation; thus, novel fluid treatments are needed to reduce such posttraumatic complications.	22777113
Inflammation, Staphylococcus aureus infection, Atopy, Exacerbation of cGVHD, Eczema	Altered Intercellular Communication	S aureus infection leads to exacerbation of eczema and may induce flares in atopic skin by mediating inflammation.	22777229
Inflammation, Pelvic Organ Prolapse, Irritation, Gastrointestinal mucositis	Altered Intercellular Communication	It is possible that pelvic organ prolapse caused irritation and inflammation of vaginal epithelium and contributed to the development of plasma cell mucositis in these areas.	22777378
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	Crohn disease (CD) is primarily considered an inflammatory condition of the small and large intestine although associated extraintestinal inflammation is relatively common.	22777510
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	Crohn disease (CD) is primarily considered an inflammatory condition of the small and large intestine although associated extraintestinal inflammation is relatively common.	22777510
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Glycoprotein 96 perpetuates the persistent inflammation of rheumatoid arthritis.	22777994
Refractory anemias, Arthritis	Altered Intercellular Communication	Supporting the role of gp96 in RA, joint tissue gp96 expression was induced in mice with the K/BxN serum-induced arthritis, and neutralizing antibodies to gp96 ameliorated joint inflammation, as determined by clinical and histologic examination.	22777994
Communicable Diseases, Inflammation, Neoplasms	Altered Intercellular Communication	FDG is not tumor specific; it can accumulate in inflammation, infection, and post-therapy settings.	22778055
Inflammation, Hemorrhage, Gangrene, Fibrosis Assessment, Edema, Malignant Neoplasms	Altered Intercellular Communication	Her histology described 'haemorrhage within the gallbladder wall along with oedema, fibrosis and patchy inflammation and no signs of malignancy or gangrene'.	22778467
Inflammation, Goblet Cells, Squamous metaplasia	Altered Intercellular Communication	Histological findings of inflammation for all specimen and mucous cell prosoplasia, squamous metaplasia, glandular epithelium for all DFs were stained with hematoxyline and eosin, periodic acid schiff, alcian blue, and mucin.	22778705
Inflammation, Goblet Cells, Squamous metaplasia	Altered Intercellular Communication	The histologic examinations showed 16% mucous cell prosoplasia, 54% squamous metaplasia, 20% glandular epithelium, 37% inflammation.	22778705
Inflammation	Altered Intercellular Communication	Inflammation was detected in all RCs and %62 in DF, %43 in DC and KCOT.	22778705
Inflammation	Altered Intercellular Communication	The results of this study indicated that the higher MCM-2 expressions in RC than the KCOT might be related to the inflammation and this protein might be more sensitive to inflammation.	22778705
Inflammation, Interstitial inflammation, Neoplasms, Pneumonitis, CTCAE, Fibrosis Assessment	Altered Intercellular Communication	The cases were categorised on the basis of histopathology into six patterns: (1) adequate biopsy without a specific diagnostic abnormality (n = 137, 22.3%); (2) acute pneumonitis (n = 29, 4.7%); (3) neoplasia (n = 109, 17.7%); (4) chronic interstitial inflammation with or without fibrosis (n = 138, 22.4%); (5) granulomatous inflammation, (n = 186, 30.2%); and (6) other specific causes (n = 16, 2.6%).	22779117
Inflammation, Periodontitis	Altered Intercellular Communication	Sites of inflammation were identified on subjects with moderate-to-severe chronic periodontitis, and were allocated to either patch placement or untreated controls, both for 24 hours.	22779219
Gingivitis	Altered Intercellular Communication	This pilot study indicates that a topical gingival patch promotes reduction of gingival inflammation.	22779219
Inflammation, Dental caries	Altered Intercellular Communication	The results demonstrated a relatively high caries experience, low level of gingival inflammation and relation between GI and DMFT, particularly in D component, and between GI and orthodontic anomalies.	22779381
Inflammation, Periodontal Diseases, Obesity	Altered Intercellular Communication	Alpha-defensins may play a role in gingival inflammation, and be involved in the higher susceptibility of obese patients to periodontal diseases.	22780105
Periodontal Infection	Altered Intercellular Communication	To investigate whether low-grade inflammation-related factors such as serum low-density (LDL-C) and high-density lipoprotein cholesterol (HDL-C) modify the association between periodontal infection and C-reactive protein.	22780440
Periodontal Infection	Altered Intercellular Communication	This study suggests that the relation of periodontal infection to the systemic inflammatory condition is more complicated than previously presumed.	22780440
Inflammation	Altered Intercellular Communication	Base excision repair gene polymorphisms are associated with inflammation in patients undergoing chronic hemodialysis.	22780951
Inflammation	Altered Intercellular Communication	Chronic inflammation may increase the risk of mortality for patients undergoing hemodialysis, while enhanced oxidative stress and DNA oxidative damage are involved in the inflammatory response.	22780951
Malignant neoplasm of esophagus, Inflammation, Hindi language, Intraepithelial Neoplasia	Altered Intercellular Communication	Among them, 88 were pathology-proven inflammation, 5 were pathology-proven esophageal cancers, 20 were pathology-proven low intraepithelial neoplasia (LIN) and 33 were pathology-proven high intraepithelial neoplasia (HIN) detected with NBI-ME.	22781948
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	By a per-lesion analysis, the accuracy of inflammation and cancer were 100% (88/88) and 7/7.	22781948
Primary malignant neoplasm, Esophagitis	Altered Intercellular Communication	Higher diagnostic accuracy of IPCL indicates the feasibility of NBI-ME for the efficacious diagnosis of esophageal inflammation and cancer.	22781948
Asthma	Altered Intercellular Communication	Chronic endobronchial inflammation is a hallmark of pediatric asthma and involves the arachidonic acid pathway.	22782807
Inflammation, Prostate carcinoma, Structure of posterior cerebral artery	Altered Intercellular Communication	Inflammation has been implicated in prostate cancer (PCa) pathogenesis.	22782910
Autoimmune Diseases, Endocrine System Diseases	Altered Intercellular Communication	Tests for autoantibodies indicating autoimmune disease were also negative, and hormonal assays for the detection of endocrine disease were normal.	22782959
Inflammation	Altered Intercellular Communication	Ultrasound showed no evidence of inflammation of pancreas.	22783000
Inflammation	Altered Intercellular Communication	11beta-HSD1 expression within bone also increases with age and inflammation.	22783780
Osteoporosis	Altered Intercellular Communication	This implicates locally produced glucocorticoids in age-related and inflammation-associated osteoporosis.	22783780
Inflammation	Altered Intercellular Communication	Activity increases with joint inflammation and could represent a local anti-inflammatory system.	22783780
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Chronic inflammation that occurs with aging is one of the risk factors for cardiovascular disease.	22784030
Cardiovascular morbidity, Inflammation	Altered Intercellular Communication	Regular exercise may prevent cardiovascular morbidity by decreasing chronic systematic inflammation.	22784030
Communicable Diseases, Inflammation, Stenosis	Altered Intercellular Communication	In adults, secondary proximal irreversible fibrotic strictures or bony changes around the nasolacrimal duct typically arise from chronic inflammation or low grade infection.	22784678
Neoplasms, Aspects of congenital malformations, Swelling, Diverticulum, Dermoid Cyst	Altered Intercellular Communication	The differential diagnosis of medial canthal swellings centered on the lacrimal sac spans malformations, diverticula, dermoid/epidermoid cysts, sac inflammations/infections causing swelling without generalized sac enlargement, encephaloceles and primary epithelial tumors, as well as extrinsic tumors impinging on the sac.	22784678
Sarcoidosis, Granulomatous, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Sarcoidosis is a non-caseating, granulomatous, epithelioid inflammation.	22784795
Muscle damage, Inflammation	Altered Intercellular Communication	Mini-midvastus versus medial parapatellar approach in TKA: muscle damage and inflammation markers.	22784897
Airway structure	Altered Intercellular Communication	Further, treatment children had a greater decrease in exhaled nitric oxide (-9.62 vs -0.39, P = .03), suggesting reduction in airway inflammation.	22785264
Inflammation	Altered Intercellular Communication	Low-grade inflammation offers a possible biological pathway, which has been confirmed in men but not in women.	22786845
Inflammation, Postoperative Complications, Extravasation of lymph, Lymphedema	Altered Intercellular Communication	Various postoperative complications (inflammation and wound dehiscence, lymphorrhoea, lymphocyst and limb lymphedema) developed in 9 (21.9%) and the local regional recurrence was recorded in 7 (17%) patients.	22788055
Inflammation, Hypereosinophilia, Unspecified visual loss	Altered Intercellular Communication	The present case strongly suggests that the occurrence of visual loss in the context of systemic inflammation with hypereosinophilia should lead to considering the diagnosis of CSS.	22789694
hearing impairment, Inflammation, Cochlear Nerve	Altered Intercellular Communication	We presume that the hearing impairment was due to auditory nerve neuritis related to extension of inflammation of the meninges.	22790140
allergic inflammation	Altered Intercellular Communication	These chemoattractants are selective for leukocyte subsets involved in acute inflammatory responses and allergic inflammation.	22790593
Sepsis, Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	REsearching severe Sepsis and Organ dysfunction in children: A gLobal perspective (RESOLVE), a phase III trial of drotrecogin alfa (activated) in pediatric severe sepsis, examined biomarker changes in inflammation and coagulation.	22791090
Inflammation, Observation Method - Coagulation, Congenital Abnormality	Altered Intercellular Communication	While children in the RESOLVE trial were similar to adults in that they showed a relationship between severity of coagulation and inflammation abnormalities and mortality, their pharmacodynamic response to drotrecogin alfa (activated) differed with respect to changes in protein C activity and systemic inflammation.	22791090
Airway structure	Altered Intercellular Communication	The data should be considered in the interpretation of FeNO levels in clinical practice and setting up FeNO screening criteria for identification of eosinophilic airway inflammation.	22791639
Myocarditis, Cardiomyopathies	Altered Intercellular Communication	Slowly resolving global myocardial inflammation/oedema in Tako-Tsubo cardiomyopathy: evidence from T2-weighted cardiac MRI.	22791656
Pain Distress Question, Arthritis, Inflammation, Federated States of Micronesia	Altered Intercellular Communication	The authors examined the incidence of secondary FM in an early inflammatory arthritis cohort, and assessed the association between pain, inflammation, psychosocial variables and the clinical diagnosis of FM.	22791744
Inflammation, Federated States of Micronesia, Pain Distress Question	Altered Intercellular Communication	Although inflammation was not associated with the clinical diagnosis of FM, pain severity and poor mental health were associated with the clinical diagnosis of FM.	22791744
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Pulmonary Emphysema	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) related to wood smoke exposure is characterized by important inflammation of the central and peripheral airways without significant emphysema.	22791990
Lung Injury, Diaphragmatic Hernia, Chronic lung disease	Altered Intercellular Communication	The development of chronic lung disease was caused by lung injury under high oxidative and inflammatory conditions in the setting of a diaphragmatic hernia.	22791992
palladium	Altered Intercellular Communication	PD has a complex profile of neurochemical deficits in which abnormalities of different neurotransmitter systems may play significant and differing roles in the development of non-motor features.	22792235
Inflammation, Organ Dysfunction Scores, Atherosclerosis	Altered Intercellular Communication	In summary, the altered plasma proteins in LHD implicated accelerated atherosclerosis, defective antioxidative activity, increased inflammation/infection, and organ dysfunction.	22792249
Perifolliculitis	Altered Intercellular Communication	In 1-9 year-olds, the prevalence of trachomatous inflammation-follicular (TF) was 17.5% (95% CI: 15.7-19.5%).	22792311
glycation, Inflammation, Endothelial dysfunction, Diabetic Angiopathies	Altered Intercellular Communication	Formation of advanced glycation endproducts (AGEs), endothelial dysfunction, and low-grade inflammation are intermediate pathways of hyperglycemia-induced vascular complications.	22792314
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Compared to placebo, benfotiamine did not result in significant reductions in plasma or urinary AGEs or plasma markers of endothelial dysfunction and low-grade inflammation.	22792314
Inflammation, Airway Obstruction	Altered Intercellular Communication	However, it is unclear, based on our current understanding of macrophage functional heterogeneity, if immature AM improve viral clearance or contribute to inflammation and airway obstruction in the IFNg-deficient neonatal lung environment.	22792355
Inflammation, Myocardial Ischemia, Atherosclerosis	Altered Intercellular Communication	We compared new non-lipid atherosclerosis indexes related to inflammation and macrophage stimulation (serum concentration of cystatin C, matrix metalloproteases and chitotriosidase activity) with common inflammatory (high sensitivity C reactive protein) and lipid markers in elderly persons and patients with atherosclerosis and ischemic heart disease who have undergone coronary bypass surgery.	22792735
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	It has been shown that changes of nitrite could be observed in acute inflammation of upper airways and in a person with diagnosed mild chronic obstructive pulmonary disease, while changes of other ions could also be observed.	22796027
Inflammation, Metabolic Syndrome X, Schizophrenia	Altered Intercellular Communication	Relationship between inflammation and metabolic syndrome following treatment with paliperidone for schizophrenia.	22796278
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome and antipsychotic medications are associated with inflammation.	22796278
Inflammation, Metabolic Syndrome X, Schizophrenia	Altered Intercellular Communication	This study investigated the relationship between inflammation and metabolic syndrome in patients with schizophrenia.	22796278
Schizophrenia, Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Schizophrenic patients with high levels of inflammation should be carefully monitored for metabolic syndrome.	22796278
Inflammation, Schizophrenia, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Moreover, strategies to reduce inflammation and obesity may prevent metabolic syndrome in patients with schizophrenia who take atypical antipsychotic medication.	22796278
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	Patients with noninfectious uveitis seen between 1979 and 2007 at 4 academic ocular inflammation specialty clinics.	22796306
Ocular Hypotension, Uveitis	Altered Intercellular Communication	The risk of hypotony is low among eyes with noninfectious uveitis, but is more frequently observed in cases with anterior segment inflammation.	22796306
Inflammation	Altered Intercellular Communication	Signs of present or past inflammation were associated with greater risk, suggesting excellent inflammatory control may reduce the risk of hypotony.	22796306
Hyperlipidemia, Hypertension, CTCAE, Inflammation, Atherosclerosis	Altered Intercellular Communication	There are many factors contributing to the progression of atherosclerosis, including hypertension, hyperlipidemia, the renin-angiotensin system, and inflammation.	22796540
Inflammation	Altered Intercellular Communication	In these patients, the chronic low-grade inflammation may predispose to vascular remodelling and arterial stiffening.	22796713
Inflammation	Altered Intercellular Communication	Upregulation of D6 in AMs could indicate that, besides its known scavenger activity in acute inflammation, D6 may have additional roles in chronic inflammatory conditions possibly promoting immune activation.	22797410
ARCN1 gene	Altered Intercellular Communication	We, therefore, investigated the involvement of D6 in the immune responses in COPD, a chronic inflammatory condition of the lung.	22797410
Inflammation	Altered Intercellular Communication	Upregulation of D6 in AMs could indicate that, besides its known scavenger activity in acute inflammation, D6 may have additional roles in chronic inflammatory conditions possibly promoting immune activation.	22797410
Inflammation, Acute infectious disease	Altered Intercellular Communication	On examination there was dried blood overlying the right ear drum and very mild inflammation of the canal but no obvious acute infection.	22797479
Behcet Syndrome	Altered Intercellular Communication	Inflammation surrounding the vertebral spinous processes as spondylarthritis in Behcet's disease.	22797948
Inflammation, Behcet Syndrome	Altered Intercellular Communication	Here, we present two Behcet's disease (BD) patients with an uncommon complication: inflammation surrounding the spinous processes revealed by positron emission tomography/computed tomography (PET/CT).	22797948
Inflammation, Spanish Language, Spondylarthritis	Altered Intercellular Communication	However, inflammation around the spinous processes should be regarded as a possible uncommon finding of seronegative spondyloarthropathy (SpA) in BD patients.	22797948
Pleurisy, Fever, CTCAE, Autosomal recessive inheritance, Brucellosis	Altered Intercellular Communication	Familial Mediterranean fever is an autosomal recessive disease characterized by recurrent fever and peritoneal and pleural inflammation.	22798132
Inflammation	Altered Intercellular Communication	Dissociation of pentameric CRP (pCRP) into pro-inflammatory monomers (mCRP) may directly link CRP to inflammation.	22798388
Vascular Diseases, Mucopolysaccharidosis I	Altered Intercellular Communication	MPs containing mCRP were able to bind to the surface of endothelial cells and generate pro-inflammatory signals in vitro, suggesting a possible role of MPs in transport and delivery of pro-inflammatory mCRP in vascular disease.	22798388
Inflammation, Complications of Diabetes Mellitus	Altered Intercellular Communication	Therefore, periodontal therapy could influence metabolic control or systemic inflammation leading to diabetic complications.	22799126
Keratitis	Altered Intercellular Communication	The features and extent of corneal inflammation, degree of involvement of subbasal nerve plexus and endothelial cell density were evaluated.	22799438
Inflammation, Myasthenia Gravis	Altered Intercellular Communication	It significantly distinguished from myasthenia gravis (MG) and local non-specific inflammation (F = 24.46, P = 0.000).	22800425
Inflammation	Altered Intercellular Communication	In addition, from the view of concomitant symptoms, local aching was very frequent in local non-specific inflammation (all 60 cases) and MVI (44 cases) patients (Chi2 = 36.346, P = 0.000).	22800425
Inflammation	Altered Intercellular Communication	MG, MVI and local non-specific inflammation are the most frequent causes.	22800425
Primary malignant neoplasm	Altered Intercellular Communication	Interleukin-l7 (IL-17), which exerts strong pro-inflammatory effects, has emerged as an important mediator in inflammation-associated cancer.	22800829
Inflammation, Virus Diseases, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Although 97% of children with clinically or biopsy-diagnosed myocarditis at presentation survived to transplantation, they had significantly higher posttransplantation mortality compared with children without myocarditis, raising the possibility that preexisting viral infection or inflammation adversely affects graft survival.	22800850
Nose Diseases, IL13 gene	Altered Intercellular Communication	Allergic rhinitis (AR) is a symptomatic disorder of the nose induced after allergen exposure by an IgE-mediated inflammation of the nasal mucosa.	22801008
Obstruction, Inflammatory disease of mucous membrane	Altered Intercellular Communication	These results suggest a relationship between nasal temperature and nasal mucosa inflammation and obstruction.	22801008
Inflammation, Craniosynostosis	Altered Intercellular Communication	A combination of oral and nasal FeNO measurements is useful to monitor the extent of inflammation in CRS patients.	22801009
Airway structure, Craniosynostosis	Altered Intercellular Communication	Reduction of oral FeNO levels may reflect a cessation of the underlying lower airway inflammation that is characteristic of ECRS.	22801009
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Research has found evidence that chronic inflammation may promote atherosclerotic disease.	22801014
Inflammation, Tuberculosis	Altered Intercellular Communication	The result of pathologic examination was reported as caseating granulomatous inflammation compatible with tuberculosis.	22801175
Inflammatory disease of mucous membrane, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	Cervical intraepithelial neoplasia is associated with genital tract mucosal inflammation.	22801340
Inflammation	Altered Intercellular Communication	The observed mucosal inflammation suggests a mechanism that may also contribute to the epidemiologic link between persistent HPV and HIV.	22801340
Hemangioma	Altered Intercellular Communication	Accuracy rates of them were not different in hemangioma (P=0.277) and infection-inflammation (P=0.470).	22801441
Hemangioma of liver, Fatty degeneration	Altered Intercellular Communication	Small needles can be successfully used as well as large ones in focal steatosis, infection-inflammation, and hemangioma of liver in unclear diagnosis.	22801441
Pulmonary Embolism	Altered Intercellular Communication	The possibility that pulmonary embolism arises de novo in the lungs, due to local inflammation-driven coagulation, needs to be considered.	22801962
Inflammation, Fibrosis Assessment, Retractile Mesenteritis	Altered Intercellular Communication	Histopathology of the mesentery and omentum showed chronic inflammation and fibrosis, supporting a diagnosis of sclerosing mesenteritis.	22802373
Infection, prostatitis	Altered Intercellular Communication	Prostatic inflammation is associated with infections penetrating through the urethra.	22803119
Calcinosis, atherosclerotic	Altered Intercellular Communication	These data suggest that while an intervention of this nature improves vascular tone, it does not exert significant effects on serum biomarkers related to atherosclerotic inflammation and calcification.	22803952
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	However, little is known about how LPS regulates pathogenesis of chronic rhinosinusitis with nasal polyps, a major form of eosinophilic inflammation in the upper airway.	22805469
Asthma, MS4A2 wt Allele, Bronchitis	Altered Intercellular Communication	To explore the association of different adiposity types with self-reported asthma, bronchial inflammation and lung function, accounting for possible effect modifiers, such as atopy and gender.	22805471
Inflammation	Altered Intercellular Communication	Of the 35 patients, 33 (94%) had at least one MD-CTE finding of active or chronic pouch inflammation and 27 patients (77%) had at least one MD-CTE finding of active pouch inflammation.	22805666
Inflammation	Altered Intercellular Communication	In patients who had IPAA surgery, findings on MD-CTE correlate positively with findings on pouch endoscopy and histopathology and are sensitive measures for pouch inflammation with high positive predictive value.	22805666
Inflammation, Obesity	Altered Intercellular Communication	Systemic inflammation in childhood obesity: circulating inflammatory mediators and activated CD14++ monocytes.	22806355
Inflammation	Altered Intercellular Communication	Muscle characteristics in patients with chronic systemic inflammation.	22806369
Inflammation, Muscular Atrophy	Altered Intercellular Communication	There is increasing clinical evidence for a strong correlation between chronic systemic inflammation and age-related muscle wasting.	22806369
Refractory anemias, Inflammation, Rheumatoid Arthritis, Degenerative polyarthritis	Altered Intercellular Communication	As a model for chronic systemic inflammation, we included 10 patients suffering from rheumatoid arthritis (RA) and 27 control patients suffering from osteoarthritis (OA).	22806369
Refractory anemias, Inflammation	Altered Intercellular Communication	These results suggest there is no association between chronic systemic inflammation in RA and age-related muscle characteristics.	22806369
Hepatic inflammation, fibrogenesis	Altered Intercellular Communication	Here we studied TGFb as well as other factors produced by HCV-specific intrahepatic lymphocytes (IHL) and peripheral blood cells in hepatic inflammation and fibrogenesis.	22806830
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	HCV-specific TGFb, not interleukin (IL)-10, inversely correlated with liver inflammation (R = -0.63, P = 0.008) and, unexpectedly, fibrosis (R = -0.46, P = 0.05).	22806830
Inflammation, Hyperplasia	Altered Intercellular Communication	This finding has been associated with either inflammation or hyperplasia in prior case series.	22807581
Inflammation, Brain Injury, Chronic	Altered Intercellular Communication	Despite a lack of a specific etiologic agent, evidence suggests multinucleated epithelial giant cells are the consequence of inflammation, chronic injury, or cellular degeneration.	22807581
HD Term Type, Inflammation, hepcidin	Altered Intercellular Communication	In conclusion, in the currently studied cohort of chronic HD patients, hepcidin-25 was a marker for iron stores and erythropoiesis and was associated with inflammation.	22808058
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Physical activity (PA) is beneficial to overall health, in part due to physiological changes that lower risk factors for cardiovascular disease, including reduced inflammation.	22808178
Inflammation, Carcinogenesis, Adenomatous Polyps	Altered Intercellular Communication	Expression of Abelson interactor 1 (Abi1) correlates with inflammation, KRAS mutation and adenomatous change during colonic carcinogenesis.	22808230
Inflammatory Bowel Diseases, Crohn Disease, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Clinical observations suggest that the lymphoid follicles (LFs) may play a crucial role in the pathogenesis of inflammatory bowel disease (IBD), especially in Crohn's disease (CD) as the site of initial mucosal inflammation.	22808293
Inflammation, Stricture of bile duct, Fibrosis Assessment, Primary sclerosing cholangitis, Bile Duct Neoplasms	Altered Intercellular Communication	Primary sclerosing cholangitis (PSC), which is characterized by inflammation and fibrosis and may lead to bile duct stricture over the intrahepatic or extrahepatic bile duct, is rare in children.	22808613
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Chronic inflammation in IBD is accompanied by an imbalance in the production of TX1 and Th2 cytokines.	22808797
Inflammation, Rupture, Coronary Artery Disease, Endothelial dysfunction, Dental Plaque	Altered Intercellular Communication	Inflammation plays an important role in coronary artery disease from the initiation of endothelial dysfunction to plaque formation to final rupture of the plaque.	22809439
Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Cardiovascular Diseases	Altered Intercellular Communication	Increasing evidence suggests that chronic, low-grade inflammation may be a common soil involving the pathogenesis of metabolic syndrome (MetS) and cardiovascular disease.	22810425
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Low-grade systemic inflammation, particularly elevated IL-6, predicts mortality in chronic obstructive pulmonary disease (COPD).	22811442
ARCN1 gene, Inflammation	Altered Intercellular Communication	Although altered body composition, especially increased visceral fat (VF) mass, could be a significant contributor to low-grade systemic inflammation, this remains unexplored in COPD.	22811442
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Cross-sectional associations between job strain and serum biomarkers of inflammation and endothelial dysfunction were investigated.	22813435
Inflammation	Altered Intercellular Communication	Secondary analyses explored the role of psychosocial/cardiometabolic risk factors as mediators of job stress associated inflammation in healthy workers.	22813435
Kidney Failure, Chronic, Inflammation, Cachexia	Altered Intercellular Communication	Protein-energy wasting and chronic inflammation are prevalent in patients with end-stage renal disease (ESRD).	22813921
Inflammation	Altered Intercellular Communication	An initial set of skin punch biopsies revealed extensive palisading granulomatous inflammation throughout the dermis, extending into the subcutis.	22814320
Arterial Stiffness, Inflammation	Altered Intercellular Communication	Pulsatile stress, inflammation and change in arterial stiffness.	22814403
Arterial Stiffness, Inflammation	Altered Intercellular Communication	These results demonstrate that both pulsatile stress and inflammation may be associated with arterial stiffness at any given moment in time, but change in pulsatile stress is a better predictor of change in arterial stiffness over time.	22814403
Wounds and Injuries	Altered Intercellular Communication	Chronic irritation of the skin, traumatic injury, and hormonal alterations seem to be implicated in the pathogenesis of PG.	22814624
Inflammation, Chronic disease, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Oxidative stress is associated with obesity, metabolic syndrome and inflammation, suggesting it could be an early event in the pathology of chronic diseases.	22816656
Inflammation, Malnutrition, Dyslipidemias, Atherosclerosis	Altered Intercellular Communication	In hemodialysis (HD) patients, dyslipidemia, malnutrition, inflammation and atherosclerosis are common.	22817124
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease progression has been linked to pro-inflammatory cytokines and markers of inflammation.	22817530
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Our preliminary data suggest that four genetic polymorphisms located in genes related to inflammation and immune processes could help to predict the risk of developing ESRD.	22817530
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Severe mental disorder and cardiovascular disease (CVD) are often associated, and inflammation is implicated in both disorders.	22817875
Inflammation, Schizophrenia, Bipolar Disorder	Altered Intercellular Communication	We investigated whether there is a relationship between CVD risk factors and inflammation in schizophrenia or bipolar disorder, and if second generation antipsychotics (SGA) interact.	22817875
Inflammation, Inflammatory disorder	Altered Intercellular Communication	The development of paradoxical inflammation in immune-mediated inflammatory diseases patients treated with anti TNF-a suggests that an unknown inflammatory pathway may be provoked by inhibiting TNF-a.	22818164
Inflammation, Bacterial Infections	Altered Intercellular Communication	Postmortem biochemical investigations confirmed the presence of inflammation associated with local bacterial infection.	22819527
Inflammation, Neck Soft Tissue Necrosis, CTCAE, Rupture of artery	Altered Intercellular Communication	Acute and chronic inflammation with tissue necrosis as well as post-actinic, fibrotic changes were also found in the tissues surrounding the ruptured artery wall.	22819527
Inflammation, Overweight	Altered Intercellular Communication	Lycopene intervention reduces inflammation and improves HDL functionality in moderately overweight middle-aged individuals.	22819555
Inflammation, Overweight	Altered Intercellular Communication	The management of overweight subjects by interventions aimed at reducing inflammation is highly desirable.	22819555
Inflammation	Altered Intercellular Communication	Therefore, this study examined lycopene's ability to lower systemic and high-density lipoprotein (HDL)-associated inflammation in moderately overweight middle-aged subjects.	22819555
Inflammation	Altered Intercellular Communication	Tissue inhibitor of metalloproteinases (TIMP)-3 is an inhibitor of matrix metalloproteinases, which regulates tissue inflammation, damage, and repair.	22819866
Gastrointestinal inflammation	Altered Intercellular Communication	We investigated the role of TIMP-3 in intestinal inflammation in human beings and mice.	22819866
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	To compare inflammation as assessed by ultrasound between patients with the subset erosive hand osteoarthritis (EOA) versus non-EOA.	22820060
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Levels of inflammation after treatment with TNFa antagonists are significantly associated with ADMA levels in patients with rheumatoid arthritis.	22820438
Inflammation, Infectious Endophthalmitis	Altered Intercellular Communication	Among 219 consecutive cases of 186 patients who had undergone IVTA injection for macular diseases, presumed noninfectious endophthalmitis was diagnosed if the patient showed severe inflammation in the anterior chamber and vitreous cavity within 7 days after injection but no organism was isolated on microbiological examination.	22820815
Degenerative polyarthritis, Inflammation, Clostridium	Altered Intercellular Communication	The decrease in Clostridia, a potent modulator of colonic Th17 and CD4+ regulatory T cells, was consistent with a decrease in inflammation; improved GSRS scores and OA symptoms for these OA participants.	22821424
Inflammation, Neurologic Dysfunction, Edema, Cell Death, Traumatic injury	Altered Intercellular Communication	Perturbation of neurovascular homeostasis causing oedema, inflammation and cell death is an important cause of acute and long-term neurological dysfunction after trauma.	22822039
ARCN1 gene, Inflammation	Altered Intercellular Communication	The aim of this work is to investigate if there was any correlation between inflammation factors and severity of COPD.	22822613
ARCN1 gene, Inflammation	Altered Intercellular Communication	Attenuation of systemic inflammation may offer new perspectives in the management of COPD and its comorbidities.	22822613
Neoplasms	Altered Intercellular Communication	Solitary paraspinal masses in the pediatric age group commonly occur secondary to spinal dysraphism, chronic inflammatory conditions, and tumors.	22823460
Refractory anemias, Inflammation	Altered Intercellular Communication	The most common lipid abnormality in RA is reduced levels of high-density lipoprotein (HDL) cholesterol, probably due to active inflammation.	22824166
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	This study undertakes a systematic and comprehensive analysis of brain gene expression profiles of immune/inflammation-related genes in aging and Alzheimer's disease (AD).	22824372
Data types - Address	Altered Intercellular Communication	First, immune/inflammation-related genes showed major changes in gene expression over the course of cognitively normal aging, with the extent of gene response far greater in aging than in AD.	22824372
Data types - Address	Altered Intercellular Communication	In contrast, far fewer immune/inflammation genes were significantly changed in the transition to AD (approximately 6% of immune-related probesets), with gene responses primarily restricted to the SFG and HC.	22824372
Data types - Address	Altered Intercellular Communication	Second, relatively few significant changes in immune/inflammation genes were detected in the EC either in aging or AD, although many genes in the EC showed similar trends in responses as in the other brain regions.	22824372
Data types - Address	Altered Intercellular Communication	Third, immune/inflammation genes undergo gender-specific patterns of response in aging and AD, with the most pronounced differences emerging in aging.	22824372
Inflammation, Data types - Address	Altered Intercellular Communication	Unexpectedly, the extent of innate immune gene upregulation in AD was modest relative to the robust response apparent in the aged brain, consistent with the emerging idea of a critical involvement of inflammation in the earliest stages, perhaps even in the preclinical stage, of AD.	22824372
Inflammation	Altered Intercellular Communication	Elevated plasma suPAR concentration is associated with increased mortality in various patient groups, and it is speculated that suPAR is a low-grade inflammation marker reflecting on disease severity.	22824423
Inflammation, Chronic disease	Altered Intercellular Communication	Asthma, especially among children aged 7-16 years, is usually a chronic disease and should, in many cases, be treated with anti-asthmatics counteracting inflammation.	22824566
Acute Lung Injury, Pneumonitis, Blood Coagulation Disorders	Altered Intercellular Communication	Transfusion-related acute lung injury in cardiac surgery patients is characterized by pulmonary inflammation and coagulopathy: a prospective nested case-control study.	22824931
Inflammation, Observation Method - Coagulation, Transfusion-Related Acute Lung Injury	Altered Intercellular Communication	The objective of the present study was to determine inflammation and coagulation pathways involved in the onset of transfusion-related acute lung injury.	22824931
Inflammation	Altered Intercellular Communication	In all patients, cardiac surgery was associated with systemic inflammation, evidenced by an increase in plasma levels of interleukin-6, interleukin-8, and elastase-a1-antitrypsin complexes compared with presurgery levels (p<.001).	22824931
Inflammation, Transfusion-Related Acute Lung Injury	Altered Intercellular Communication	Prior to onset of transfusion-related acute lung injury, there is systemic inflammation and neutrophil sequestration.	22824931
Acute Lung Injury, Pneumonitis	Altered Intercellular Communication	Transfusion-related acute lung injury is characterized by both systemic and pulmonary inflammation and activation of neutrophils, as well as enhanced coagulation and suppressed fibrinolysis.	22824931
Inflammation, Hepatic Vein Thrombosis, Pancreatitis, Alcoholic, Thrombophilia	Altered Intercellular Communication	Extrahepatic portal venous system thrombosis in recurrent acute and chronic alcoholic pancreatitis is caused by local inflammation and not thrombophilia.	22825367
Communicable Diseases, Inflammation, Traumatic injury, Rupture	Altered Intercellular Communication	The case of a patient who underwent an endovascular aortic repair for a spontaneous rupture of a non-aneurysmal subdiaphragmatic aorta without trauma, infection, or inflammation is reported.	22825863
Inflammation, Angina Pectoris	Altered Intercellular Communication	The independent relationship between systemic inflammation and fragmented QRS complexes in patients with stable angina pectoris.	22825938
Immediate-type hypersensitivity drug reaction, Airway structure	Altered Intercellular Communication	Challenge with K(2)PtCl(4) by a dosimeter method yielded a clear immediate-type reaction with an increase of exhaled nitric oxide from 32 to 156 ppb after 24 h indicating an increased airway inflammation.	22826048
Pleural Effusion, CTCAE, Pleurisy, Atelectasis	Altered Intercellular Communication	Chest X-ray revealed lower left lobe consolidation with pleural inflammation and chest CT showed extensive interstitial-alveolar changes in the left lung with atelectasis and pleural effusion causing a reduction in lung volume up to the fourth rib.	22826075
Bacteremia, HD Term Type, Inflammation	Altered Intercellular Communication	We retrospectively collected clinical data and healthcare costs from 15 months for 75 admitted catheter-dependent HD patients, to document the type of bacteremia (complicated or not), pathogen and inflammation.	22826145
Bacteremia, Inflammation, Anemia	Altered Intercellular Communication	Although, in patients starting dialysis on catheter (41 %) as compared to those using catheter as bridge angioaccess, inflammation (higher C-reactive protein; p = 0.006) and anemia (lower Hb; p = 0.008) were more pronounced, bacteremia occurred in a lower proportion (32 vs. 64 %, p = 0.007).	22826145
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Pathological examination demonstrated active inflammation with no evidence of malignancy.	22826630
Primary malignant neoplasm, Chronic inflammation	Altered Intercellular Communication	If cancer follows chronic inflammation, immunosuppression, or it is pure coincidence, is still a matter of debate.	22826971
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Recent studies have suggested that TH17 cells and its signature cytokine IL-17 are involved in the underlying pathogenic mechanisms leading to destructive inflammation and autoimmunity.	22827855
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Furthermore, the surgical success of glaucoma filtering surgery is compromised in patients with scarring and inflammation of the conjunctiva.	22828007
Inflammation, Compression, Swelling	Altered Intercellular Communication	Adhesiolysis was developed as a means of removing epidural scarring leading directly or indirectly to compression, inflammation, swelling, or a decreased nutritional supply of nerve roots.	22828693
Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a chronic, systemic and an autoimmune disease characterized by inflammation of the synovial membrane that affects approximately 1 % of the total world population.	22829412
ARCN1 gene, Inflammation	Altered Intercellular Communication	The etiology of COPD has been associated with apoptosis, oxidative stress, and inflammation.	22829758
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Chronic inflammation in IBD is accompanied by an imbalance in the production of Tx1 and Tx2 cytokines.	22830224
Necrotizing granulomatous inflammation, T-Cell Lymphoma, Hodgkin Disease	Altered Intercellular Communication	Cutaneous granulomatous inflammation can occur in patients with T-cell lymphoma and Hodgkin disease.	22830642
Histiocytosis, Granulomatous inflammation	Altered Intercellular Communication	Histopathology showed GA-like palisaded histiocytic infiltration, with subtle collections of lymphocytes interspersed among the granulomatous inflammation.	22830642
Granulomatous inflammation, Infiltration	Altered Intercellular Communication	Co-existence of a GA-like infiltrate and cutaneous B-CLL raises the possibility that granulomatous inflammation occurs as a secondary response to dermal infiltration by leukemic cells.	22830642
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation plays a role in the development of cardiovascular disease (CVD).	22831953
Inflammation, Obesity	Altered Intercellular Communication	Many inflammation parameters are associated with obesity, but few comparable data are found in youth.	22832157
Inflammation, Arthritis	Altered Intercellular Communication	Interleukin 1b (IL-1b) plays a central role in the pathogenesis of inflammation induced by calcium pyrophosphate crystals, and IL-1b blockade may be an effective treatment in patients with severe chronic calcium pyrophosphate crystal arthritis.	22832289
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Matrix metalloproteinase-9 (MMP-9) and its inhibitor tissue inhibitor of metalloproteinase-1 (TIMP-1) are involved in the pathogenesis of airway inflammation in patients with chronic obstructive pulmonary disease (COPD).	22832426
Airway structure	Altered Intercellular Communication	However, no study so far has addressed their value as noninvasive biomarkers of airways inflammation.	22832426
ARCN1 gene, Airway structure	Altered Intercellular Communication	Exhaled MMP-9 and TIMP-1 increased during COPD exacerbation and was negatively correlated with spirometric variables, which suggests the usefulness of their measurement in EBC for the monitoring of airways inflammation.	22832426
Depressive disorder, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Association of depressive disorders, depression characteristics and antidepressant medication with inflammation.	22832816
Inflammation, Depressed mood, Depression, CTCAE	Altered Intercellular Communication	After full adjustment, highest inflammation levels were found in depressed men with an older age of depression onset (CRP, TNF-a).	22832816
Inflammation, Depressed mood	Altered Intercellular Communication	In conclusion, elevated inflammation was confirmed in depressed men, especially those with a late-onset depression.	22832816
Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of autoantibodies and inflammation in multiple organ systems.	22833362
Inflammation, Cardiovascular Diseases, Obesity, Diabetes Mellitus	Altered Intercellular Communication	As discussed, understanding Hcy and genetic regulation is important, because Hcy may be related to inflammation, obesity, cardiovascular disease, and diabetes mellitus.	22833659
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Red cell distribution width and inflammation in patients with non-dipper hypertension.	22835009
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Non-dipper hypertension is associated with higher inflammation and worse prognosis.	22835009
Inflammation, Primary malignant neoplasm, Cardiovascular Diseases	Altered Intercellular Communication	Leukotrienes (LT) play a role in inflammation, cardiovascular diseases, and cancer.	22835628
Hyperhomocysteinemia, Arteriosclerosis Obliterans	Altered Intercellular Communication	[Inflammation of the vascular wall and hyperhomocysteinemia in patients with atherosclerosis obliterans of lower limb arteries].	22836325
Inflammation, Hyperhomocysteinemia, Ischemia, Endothelial dysfunction, Vasculitis	Altered Intercellular Communication	The comparative analysis revealed that patients with LLA had signs of chronic vascular inflammation accompanied in the majority of cases by hyperhomocysteinemia with endothelial dysfunction, as well as direct association between the degree of the vascular inflammatory reaction and severity of clinical manifestations of lower limb ischaemia.	22836325
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow limitation and chronic inflammation of airways and lung parenchyma.	22836613
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a progressive, inflammatory condition, involving airways and lung parenchyma.	22836615
Abnormality of the vasculature, Neoplasms	Altered Intercellular Communication	Orbital lesions include a broad spectrum of tumors, vascular abnormalities, and inflammatory conditions.	22836792
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	Assessment of pulmonary neutrophilic inflammation in emphysema by quantitative positron emission tomography.	22837375
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Neutrophilic inflammation is understood to be of pathogenetic importance in chronic obstructive pulmonary disease (COPD) and may be quantified using 18-fluorodeoxyglucose positron emission tomography-computed tomography ((18)FDG PET-CT) as a noninvasive, spatially informative biomarker.	22837375
ARCN1 gene, Pneumonitis, alpha 1-Antitrypsin Deficiency	Altered Intercellular Communication	To assess the potential usefulness of (18)FDG PET-CT as a surrogate measure of pulmonary neutrophilic inflammation in patients with usual COPD and a(1)-antitrypsin deficiency (AATD).	22837375
Inflammation, alpha 1-Antitrypsin Deficiency	Altered Intercellular Communication	(18)FDG uptake, lung physiology, lung density, and systemic markers of inflammation were compared for all groups at baseline and, in patients with AATD, at baseline and on treatment.	22837375
Inflammation, Hyphema	Altered Intercellular Communication	After resolution of hyphema, transient elevated intraocular pressure, and anterior chamber inflammation, best corrected visual acuity returned to 20/25 in each eye 6 months later.	22837630
Lichen Planus	Altered Intercellular Communication	Lichen planus is an autoimmune inflammatory condition in which autoreactive T lymphocytes attack keratinocytes.	22838091
Tolosa-Hunt Syndrome, Inflammation, Methylated spirit, Orbital fissure	Altered Intercellular Communication	Tolosa-Hunt syndrome (THS) is an uncommon disease caused by non-specific inflammation of the cavernous sinus, superior orbital fissure and the apex of the orbit.	22838177
Inflammation, Periodontal Diseases, Treponema	Altered Intercellular Communication	The relationship between different species of oral Treponemas and inflammation in periodontal disease progression is complex.	22838219
Inflammation, Pneumonia, Interstitial, Hyperplasia, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial pneumonia causing a loss of respiratory surface area due to a proliferative fibrotic response involving hyperplastic, hypertrophic, and metaplastic epithelium, cystic honeycomb change, septal expansion, and variable inflammation.	22838404
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	The increased risk of cardiovascular (CV) disease associated with rheumatoid arthritis (RA) is partly attributable to chronic inflammation, but traditional CV risk factors such as physical inactivity are also likely to be important.	22839595
Inflammation, atherosclerotic	Altered Intercellular Communication	Cytokines as regulators of activity of inflammation play significant role in mechanisms of formation of atherosclerotic plaques and in processes of their destabilization.	22839710
Inflammation, Fibrosis Assessment, ETV3 wt Allele	Altered Intercellular Communication	The current demonstration that MetS is associated with decrease of the pro-fibrotic PDGF cytokine is a completely novel finding, which adds complexity to the interplay between inflammation and fibrosis in patients affected by MetS.	22840561
Inflammation	Altered Intercellular Communication	Initially performed MRI of the pelvis shows predominant inflammation of the hip joint.	22840961
Immune-mediated	Altered Intercellular Communication	Accumulating evidence suggests that immune-mediated inflammation plays an important role in the pathophysiology of AMI, but the mechanism that triggers such immune responses is unknown.	22841473
Inflammation, Prediabetes syndrome	Altered Intercellular Communication	The obtained results suggest that metformin may inhibit monocyte secretory function and reduce systemic inflammation in statin-treated patients with prediabetes.	22841520
Dental Plaque	Altered Intercellular Communication	Inflammation within atheromatous plaques is a known risk factor for plaque vulnerability.	22841932
Autosomal Recessive Disorder, Inflammation, Fever, CTCAE, Brucellosis	Altered Intercellular Communication	Familial Mediterranean fever is an autosomal recessive disorder characterized by paroxysmal episodes of fever and serosal inflammation.	22842301
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	Resistin is a polypeptide hormone that was reported to be associated with insulin resistance, inflammation and risk of type 2 diabetes and cardiovascular disease.	22843503
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	Resistin is a polypeptide hormone that was reported to be associated with insulin resistance, inflammation and risk of type 2 diabetes and cardiovascular disease.	22843503
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Nuclear factor-kappa B (NFkB) is a major regulator of inflammation and variation in NFkB-associated genes could potentially be used as biomarkers to identify patients with increased risk of colorectal cancer (CRC) development, and/or a rapidly progressing disease.	22843550
Malignant neoplasm of urinary bladder	Altered Intercellular Communication	Utility of inflammation-based prognostic scoring in patients given systemic chemotherapy first-line for advanced inoperable bladder cancer.	22844127
Inflammation, Cicatricial ectropion	Altered Intercellular Communication	The eyelid inflammation decreased but severe scarring of the marginal eyelids persisted, resulting in cicatricial ectropion.	22845188
HD Term Type, Cardiac complication, Inflammation	Altered Intercellular Communication	Chronic inflammation in hemodialysis (HD) patients is associated with cardiovascular complications and mortality.	22845695
HD Term Type, Inflammation	Altered Intercellular Communication	We intended to test the feasibility of using a high cutoff (HCO) dialyzer in chronic HD patients and its influence on inflammation and monocyte activation.	22845695
Inflammation, Infant, Premature	Altered Intercellular Communication	In the rLD and sVD/PD groups, risk factors, such as prematurity and fetal inflammation, co-existed.	22845749
Inflammation	Altered Intercellular Communication	On the other hand, old birds showed imbalanced levels of inflammatory markers toward a pro-inflammatory status, thereby underlining the fact that aging is usually accompanied by systemic inflammation and inflammation-related chronic diseases.	22846077
Inflammation	Altered Intercellular Communication	We report here two cases of fatal lime sulfide poisoning with several related cases and in addition induced histological damage with acute inflammation in animal models under at similar concentrations.	22847057
Inflammation, Malaria, Anemia	Altered Intercellular Communication	We found high prevalence of anemia, malaria, inflammation, and deficiencies of iron, riboflavin, and vitamin A but low prevalence and intensities of soil-transmitted helminth and schistosome infections.	22848097
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Myocardial biopsies from Apoe(-/-) mice demonstrated signs of chronic inflammation with fibrosis, increased apoptosis and expression of IL-6, as compared to biopsies from C57BL/6J control mice.	22848603
Neoplasms	Altered Intercellular Communication	Tumor and stroma are additional sources of inflammation-related molecules.	22848630
Carcinogenesis, Colorectal Carcinoma, Adenoma of large intestine	Altered Intercellular Communication	Combined quantification of serum IL-8, MMP-9 and CRP, appears a reliable and advanced index of inflammation-related processes during malignant phase of colorectal carcinogenesis, since these molecules remain within normal range in colorectal adenoma bearing patients, while consistently increase in the blood of CRC patients, even if from stage II only.	22848630
Extrinsic allergic alveolitis, Granulomatous inflammation, Pneumonia, Interstitial, Chronic bronchiolitis	Altered Intercellular Communication	Her biopsy showed honeycomb change and fibroblast foci suggestive of usual interstitial pneumonia, but also showed areas of cellular interstitial pneumonia with chronic bronchiolitis and a pattern of granulomatous inflammation typical of hypersensitivity pneumonia.	22849736
Myocarditis	Altered Intercellular Communication	Different etiologies of pericardial inflammation did not influence the IFN-gamma levels.	22850905
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Genetic factors regulating inflammation and DNA methylation associated with prostate cancer.	22850906
Inflammation, Prostate carcinoma, Structure of posterior cerebral artery	Altered Intercellular Communication	Prostate cancer (PCa) displays a strong familiarity component and genetic factors; genes regulating inflammation may have a pivotal role in the disease.	22850906
Inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	The complement system plays an important role in tissue inflammation and damage in SLE patients.	22851413
Celiac Disease, Stenosis	Altered Intercellular Communication	SBCE findings were classified as clinically significant/sinister (small-bowel malignancy, significant/sinister inflammation and/or strictures and coeliac disease) or vascular, i.e., signifcant/angioectasias (P1/P2 lesions).	22852553
Inflammation, Primary malignant neoplasm, Depression, CTCAE	Altered Intercellular Communication	Interrelationship of depression, stress and inflammation in cancer patients: a preliminary study.	22854100
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Inflammation in the walls of asymptomatic abdominal aortic aneurysms is not associated with increased metabolic activity detectable by 18-fluorodeoxglucose positron-emission tomography.	22854268
Inflammation	Altered Intercellular Communication	The chronic inflammation observed in the wall of asymptomatic AAAs was not sufficiently metabolically active to result in an increased glucose metabolism detectable by FDG-PET by means of this standard protocol.	22854268
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Neutrophil to lymphocyte ratio (NLR), an index of systemic inflammation, has been associated with worse survival for many types of cancer.	22855161
Inflammation, Fever, CTCAE, Hypertrophy	Altered Intercellular Communication	They were affected by chronic hypertrophic tonsillitis with a recurrent fever and other symptoms that were related to oral inflammation.	22855380
Edema, Acute inflammation, Exudate	Altered Intercellular Communication	Minor complications included sore throat, moderate oedema, mild acute pharynx inflammation, slight peritonsillar exudate and local burning.	22855380
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Targeted folate receptor b fluorescence imaging as a measure of inflammation to estimate vulnerability within human atherosclerotic carotid plaque.	22855837
Inflammation, Depression, CTCAE, Atherosclerosis	Altered Intercellular Communication	Inflammation and atherosclerosis play an important role in the pathogenesis of depression.	22856651
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	One of the major pathophysiologies in advanced chronic obstructive pulmonary disease (COPD) has been attributed to systemic inflammation.	22857881
Dyssomnias, Inflammation, Primary malignant neoplasm, Depression, CTCAE	Altered Intercellular Communication	Sleep problems and depression are modifiable host factors that can influence inflammation and impact cancer progression and quality of life.	22858235
Electrocardiogram: myocardial infarction (finding), Ischemic stroke, Plaque, Atherosclerotic	Altered Intercellular Communication	Inflammation of an atherosclerotic plaque is a well-known risk factor in the development of ischemic stroke and myocardial infarction.	22859280
Inflammation, Dental Plaque	Altered Intercellular Communication	MR imaging is capable of characterizing inflammation by assessing plaque enhancement in both extracranial carotid arteries and coronary arteries.	22859280
Pain Distress Question, Inflammation, Primary gout	Altered Intercellular Communication	To evaluate the analgesic efficacy of high-dose celecoxib in the treatment of moderate to extreme pain and inflammation associated with acute gouty arthritis.	22859357
Pain Distress Question, Inflammation	Altered Intercellular Communication	Sympathetically maintained pain may occur when primary afferent neurons are excited by inflammation due to VZV infection.	22860307
Inflammation, Aggressive behavior, Hyponatremia	Altered Intercellular Communication	Furthermore, hyponatremia might be significantly associated with chronic inflammation and tumor aggressiveness.	22860625
Inflammation, zirconium oxide	Altered Intercellular Communication	No statistically significant difference in tissues adjacent to zirconia and titanium abutment surfaces were seen with respect to vascular density (20.5 SD 4.4 and 20.7 SD 3.2) or inflammation grading scale scores (3.2 SD 0.7 versus 3.1 SD 0.7).	22862854
Inflammation, Anemia, Chronic Kidney Diseases, Vitamin B 12 Deficiency	Altered Intercellular Communication	The five most prominent causes of anaemia were inflammation (62.1%), iron deficiency (30.5%), folic acid deficiency (21%), chronic renal failure (17.9%) and cobalamin deficiency (11.6%).	22863429
Inflammation, Acute Coronary Syndrome, Heart valve calcification	Altered Intercellular Communication	Association of serum fetuin-A levels with heart valve calcification and other biomarkers of inflammation among persons with acute coronary syndrome.	22863558
Inflammation, Hepatitis C, Liver Cirrhosis	Altered Intercellular Communication	The failure of the immune response to clear the Hepatitis C virus (HCV) results in chronic inflammation that leads to liver cirrhosis.	22863720
Inflammation, Calcification of coronary artery, SLC25A20 gene, Atherosclerosis	Altered Intercellular Communication	Several studies have demonstrated that inflammation plays a major role in the development of atherosclerosis and that the inflammatory process might also be involved in coronary artery calcification (CAC).	22864317
Diabetes Mellitus, Insulin-Dependent, Chronic inflammation	Altered Intercellular Communication	Systemic exposure to Pseudomonal bacteria: a potential link between type 1 diabetes and chronic inflammation.	22864910
Diabetic Nephropathy, Inflammation	Altered Intercellular Communication	Bacterial endotoxins have been associated with chronic inflammation and the development and progression of diabetic nephropathy.	22864910
Inflammation, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8	Altered Intercellular Communication	These findings indicate that recurrent or chronic Pseudomonal exposure may increase susceptibility to chronic inflammation in patients with T1D.	22864910
Inflammation, Non-communicable Chronic Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Low-grade chronic systemic inflammation is often associated with chronic non-communicable diseases, and its most frequently used marker, the C-reactive protein (CRP), has become an identifier of such diseases as well as an independent predictor for cardiovascular disorders and mortality.	22865000
Inflammation, Overweight, muscle mass	Altered Intercellular Communication	Intervention procedures to treat low-grade chronic inflammation in overweight women would mainly focus on restoring muscle mass and functions in addition to an antioxidant-rich diet.	22865000
Granulomatous Mastitis, Inflammation, Tuberculosis of breast	Altered Intercellular Communication	In 62 patients, there were benign lesions (fibroadenomas, fibrocysts), and four patients had inflammation (granulomatous mastitis in two patients, breast tuberculosis in two patients).	22865198
Inflammation	Altered Intercellular Communication	Yet, the role of inflammation following transcatheter aortic valve implantation (TAVI) has not been fully elucidated.	22865312
Communicable Diseases, Inflammation, Bacterial Infections	Altered Intercellular Communication	In intensive care unit (ICU) patients, signs of infection and inflammation are similar, making diagnosis of bacterial infections difficult.	22865497
Inflammation, Irritation, Dryness of eye, Eye pain	Altered Intercellular Communication	A number of ocular conditions, such as dry eye, are associated with inflammation on the surface of the eye leading to irritation and ocular pain.	22867431
vascular inflammations, Hypertensive (finding), Hypertension, CTCAE	Altered Intercellular Communication	Death-associated protein kinase 3 mediates vascular inflammation and development of hypertension in spontaneously hypertensive rats.	22868392
vascular inflammations, Hypertension, CTCAE	Altered Intercellular Communication	Pathogenesis of hypertension is modulated at least in part by vascular inflammation.	22868392
Inflammation, Hypertensive (finding), Hypertension, CTCAE, Hypertrophy	Altered Intercellular Communication	It is also suggested that DAPK3 mediates the development of hypertension in spontaneously hypertensive rats likely via ROS-dependent inflammation, hypertrophy, and hypercontractility.	22868392
Asthma	Altered Intercellular Communication	In elder patients with asthma, treatment with BUD/FM does not have any clinical disadvantage and may provide better efficacy in lung function, QOL, and possibly anti-inflammation compared with BUD plus Tulo treatment.	22868522
Inflammation, Primary malignant neoplasm, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation has been implicated in the pathogenesis of cardiovascular disease, type 2 diabetes mellitus and cancer.	22868815
Inflammation	Altered Intercellular Communication	However, as this case shows, it may primarily involve the posterior uvea without anterior inflammation and may recur.	22870033
Renal Cell Carcinoma Pathway, Bipolar Disorder	Altered Intercellular Communication	Depressive symptoms and cortisol rhythmicity predict survival in patients with renal cell carcinoma: role of inflammatory signaling.	22870317
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	Animal and pathological studies suggest that inflammation may contribute to amyotrophic lateral sclerosis (ALS) pathology and that non-steroidal anti-inflammatory drugs (NSAIDs) might be protective.	22871075
ARCN1 gene, Bronchitis	Altered Intercellular Communication	Cysteinyl leukotriene 1 receptor expression associated with bronchial inflammation in severe exacerbations of COPD.	22871757
Inflammation	Altered Intercellular Communication	Despite elevated macrophage carbon load, tunnel mice showed no overt pulmonary or systemic inflammation, yet manifested reduced pulmonary thrombomudulin expression and elevated endothelial von Willebrand factor (VWF) expression in lung capillaries.	22872007
Pneumonitis	Altered Intercellular Communication	Hence, continuous traffic-related air pollution did not trigger overt lung inflammation, yet modified pulmonary endothelial cell function and enhanced platelet activity.	22872007
Inflammation, Cartilaginous metaplasia	Altered Intercellular Communication	Each PCL was histologically evaluated for inflammation, mucinous changes, chondroid metaplasia, cystic changes and orientation of collagen fibres.	22872023
Inflammation, Metabolic Diseases, Obesity	Altered Intercellular Communication	Obesity and metabolic disorders are linked to inflammation via gut microbiota and/or gut permeability.	22872030
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Gut-derived endotoxin triggers inflammation leading to metabolic syndrome (MetS) and contributing to oxidative stress.	22872030
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Effects of active smoking on airway and systemic inflammation profiles in patients with chronic obstructive pulmonary disease.	22874622
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The markers that characterize local and systemic inflammation in chronic obstructive pulmonary disease (COPD) remain unclear, as do their correlations with smoking status and presence of disease.	22874622
ARCN1 gene, Inflammation, Smoking	Altered Intercellular Communication	Smoking is associated with higher systemic inflammation in patients with COPD.	22874622
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histologic assessment revealed curability of ESD and inflammation and fibrosis around EIS site.	22874708
Inflammation, Edema, Ulcer	Altered Intercellular Communication	At day 0, both lower legs had significant oedema and circumferential venous-lymphatic ulcers, and the left leg showed signs of inflammation.	22874827
Inflammation, Edema, Ulcer	Altered Intercellular Communication	However, at day 8, inflammation, oedema and ulcer area had reduced.	22874827
Inflammation	Altered Intercellular Communication	We also show that oxPL stimulation increases expression of genes involved in macrophage infiltration, inflammation, and neovascularization in the eye.	22875704
methyldopa, Inflammation	Altered Intercellular Communication	Together, these findings suggest that CFH influences AMD risk by modulating oxidative stress, inflammation, and abnormal angiogenesis.	22875704
Myocarditis	Altered Intercellular Communication	This technique holds major promise as a potential method for assessing cellular myocardial inflammation and left ventricular remodelling, which may have a range of applications in patients with MI and other inflammatory cardiac conditions.	22875883
Inflammation, polychondritis, Systemic disease	Altered Intercellular Communication	Relapsing polychondritis is a rare multisystemic disease, which is characterized by recurrent inflammation of the cartilaginous structures.	22876362
Inflammation, Cytopenia, Lymphohistiocytosis, Hemophagocytic	Altered Intercellular Communication	Macrophage activation in hemophagocytic lymphohistiocytosis (HLH) leads to severe inflammation resulting in cytopenias and multi-organ dysfunction.	22876565
Inflammation, Heart failure, Atherosclerosis	Altered Intercellular Communication	Systemic inflammation has been linked to the development of heart failure in population studies including Multi-Ethnic Study of Atherosclerosis (MESA), but little evidence exists regarding potential mechanism of this relationship.	22877812
Liver carcinoma	Altered Intercellular Communication	Comparison of the prognostic value of inflammation-based prognostic scores in patients with hepatocellular carcinoma.	22878374
Refractory anemias, Bone Marrow Diseases, Atlanto-Axial joint, Neck Pain	Altered Intercellular Communication	Furthermore, surgery was often recommended to RA patients, because of the neck pain induced by RA-related inflammation of the atlanto-axial joint, regardless of any underlying myelopathy.	22878378
Intraocular inflammation, Macular retinal edema	Altered Intercellular Communication	The aim of the present study was to determine SST concentration in the vitreous fluid of patients with chronic uveitic macular oedema (CUMO) and quiescent intraocular inflammation.	22878444
Intraocular inflammation	Altered Intercellular Communication	Intravitreous SST is decreased in patients with CUMO and quiescent intraocular inflammation.	22878444
Immunology	Altered Intercellular Communication	Increasing evidence indicates that AF may be associated with immunologic inflammation responses, but it remains unclear whether activation of peripheral blood CD3(+) T-lymphocytes plays a role in the pathogenesis of AF.	22878798
Pneumonitis	Altered Intercellular Communication	Prevention of hyperoxia-mediated pulmonary inflammation in neonatal rats by caffeine.	22878872
ARCN1 gene, Inflammation	Altered Intercellular Communication	Airway epithelial cell apoptosis and inflammation in COPD, smokers and nonsmokers.	22878876
Inflammation, Leukemoid Reaction, Hyperalgesia, Allodynia	Altered Intercellular Communication	Parallel to this leukemoid reaction, allodynia and hyperalgesia developed in the absence of tissue inflammation.	22878999
Inflammation, Sarcoidosis	Altered Intercellular Communication	The purpose of this study was to assess the utility of (18)F-FDG PET/CT for detection of inflammation in granulomatous sites and management of patients with chronic sarcoidosis.	22879080
Inflammation, Retinal thickening	Altered Intercellular Communication	Severity of inflammation at baseline predicts the amount of retinal thickening in affected eyes.	22879410
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Among participants with CKD, inflammation significantly modified the associations of total cholesterol and LDL-C with IMT (P values for interaction, P<0.01 and P<0.001, respectively).	22879436
Alzheimers Disease	Altered Intercellular Communication	Importantly, methylation plays a central role for neurotransmitter generation like acetylcholine pointing to a crucial relevance of our findings for Alzheimer's disease.	22879628
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	To determine whether the metabolic syndrome (MetS) or its components were more closely associated with disease states and inflammation in elderly adults.	22880886
Inflammation, Obesity, Abdominal, ETV3 wt Allele	Altered Intercellular Communication	The observation that MetS is associated with disease states and markers of circulating inflammation in the elderly is explained mainly by abdominal obesity and low HDL-C. Longitudinal data will further clarify these cross-sectional findings that MetS appears to be less than the sum of its parts in elderly adults.	22880886
Inflammation	Altered Intercellular Communication	PERIOD3 (PER3) polymorphisms have been associated with circadian disruption and changed secretion of cytokines involved in chronic inflammation.	22881285
ARCN1 gene, Chronic Obstructive Airway Disease, Bronchitis	Altered Intercellular Communication	Statin treatment may ameliorate viral infection-induced exacerbations of chronic obstructive pulmonary disease (COPD), which exhibit Th2-type bronchial inflammation.	22881993
ARCN1 gene, Inflammation	Altered Intercellular Communication	Thymic stromal lymphopoietin (TSLP), a hub cytokine switching on Th2 inflammation, is overproduced in viral and dsRNA-stimulated bronchial epithelial cells from COPD donors.	22881993
Inflammation	Altered Intercellular Communication	Oxidative stress induced by chronic inflammation could be a cause and antioxidants, including selenoproteins, may reduce the risk.	22882569
Inflammation	Altered Intercellular Communication	Oxidative stress produced by chronic inflammation could represent one of the causes, and antioxidants, including selenoproteins, may reduce the risk.	22882569
Liver Cirrhosis, Necrosis with inflammation	Altered Intercellular Communication	rtS106C, rtD134E/G/N/S and A-B interdomain mutations may be associated with necro-inflammation, immune response and cirrhosis development at ages older than 40.	22882650
Inflammation, myocardial injury	Altered Intercellular Communication	High-dose rosuvastatin loading before PCI significantly reduced periprocedural myocardial injury and periprocedural inflammation cytokines release and improved 3-month and 6-month clinical outcomes in female patients with NSTEACS who underwent PCI.	22882843
Inflammation	Altered Intercellular Communication	This was independent of age, sex, systemic inflammation and cytomegalovirus seropositivity.	22882906
Unknown (origin) (qualifier value), Inflammation	Altered Intercellular Communication	Bacterial biofilm does not seem to play a major role in the pathogenesis of idiopathic epistaxis in children (only positive in 7.1 % of cases by SEM) although a low-grade chronic inflammation is not infrequently present (37 % of cases detected by FISH).	22885868
Inflammation, With intensity	Altered Intercellular Communication	However, T2 hyperintensities in WM can also be caused by other mechanisms such as inflammation.	22886015
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) involves multiple pathological processes in the brain, including increased inflammation and oxidative damage, as well as the accumulation of amyloid-b (Ab) plaques.	22886019
Inflammation, Obesity, Abdominal, Hyperglycemia, Dyslipidemias, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	After adjustment for BMI, social-demographic, lifestyle and dietary factors and other TFAs, erythrocyte trans-18:1 was shown to be associated with a lower risk of type 2 diabetes (OR comparing extreme [first and fourth] quartiles 0.68, 95% CI 0.48, 0.97, p(trend) = 0.02), as well as 20-50% lower odds of central obesity, dyslipidaemia, hyperglycaemia, insulin resistance and chronic inflammation.	22886370
Tumor necrosis, Primary malignant neoplasm, Stomach Carcinoma, Inflammation	Altered Intercellular Communication	In tumor necrosis factor a-treated gastric cancer cells, HSP27 knockdown increased cell death and accumulation of the reactive oxygen species that link inflammation to cancer.	22886594
Gastrointestinal Hemorrhage, Intra-abdominal, Obstruction of biliary tree, Abdominal Pain, Intestinal Obstruction	Altered Intercellular Communication	Of 202 consultations, the diagnoses were wound problems (N = 39, 19%), bowel obstruction (N = 75, 37%), intra-abdominal inflammatory conditions (N = 36, 18%), abdominal pain of unclear etiology (N = 13, 6%), gastrointestinal hemorrhage (N = 15, 7%), malnutrition/feeding tube request (N = 14, 7%), and biliary obstruction (N = 10, 5%).	22886727
Inflammatory disease of mucous membrane	Altered Intercellular Communication	MMMS and FGMMS are equivalent in the amount of sinonasal mucosal inflammation and discomfort post endoscopic sinus surgery.	22888489
Inflammation, Pancreatitis Necrotizing	Altered Intercellular Communication	Results of the electron microscopic investigation of the pancreatic tissues biopsies, obtained intraoperatively from the demarcation inflammation focus, while operating 42 patients for an acute necrotic pancreatitis (ANP), were summarized.	22888547
deficiency aspects, Adenoma	Altered Intercellular Communication	Premenopausal women tended to have smaller adenomas than men, but neither adenoma size nor invasion was associated with multiple hormonal deficiency at presentation.	22889015
Inflammation	Altered Intercellular Communication	Systemic inflammation with inappropriate vasodilatation is observed in many patients with CS and may contribute to an excess mortality rate.	22889197
Inflammation, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Low-grade inflammation is linked to metabolic syndrome and obesity.	22889406
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Stat3 small interfering RNA suppressed indoxyl sulfate-induced expression of an inflammation marker gene (monocyte chemotactic protein-1), fibrosis marker genes (TGF-b(1), a-smooth muscle actin) and a subunit of nuclear factor-kB (p65), and attenuated a cellular senescence marker, senescence-associated b-galactosidase activity.	22889746
Stomach Carcinoma	Altered Intercellular Communication	Inflammation-based prognostic score predicts survival in patients with advanced gastric cancer receiving biweekly docetaxel and s-1 combination chemotherapy.	22890015
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Microglia manage immunosurveillance and mediate inflammation, both suggested to be important in Alzheimer's disease (AD).	22890100
Inflammation, Extravasation, Injury of kidney	Altered Intercellular Communication	: Mice with one functional angiopoietin-2 allele developed milder kidney and lung injury, less tissue inflammation, and less vascular leakage compared to wild-type counterparts.	22890252
Inflammation, Myocardial	Altered Intercellular Communication	MicroRNA levels were not associated with myocardial damage or activation of inflammation.	22890253
Inflammation, Psoriasis	Altered Intercellular Communication	Psoriasis vulgaris (PV) is associated with low-grade systemic inflammation.	22890310
Pseudotumor, Neoplasms	Altered Intercellular Communication	In one case we found coexistence foreign body (shot) and tumor--inflammation pseudotumor of the orbita.	22890536
Inflammation	Altered Intercellular Communication	Regular physical activity is associated with lower markers of inflammation over 10 years of follow-up and thus may be important in preventing the proinflammatory state seen with aging.	22891048
Inflammation, Metabolic Syndrome X, Cardiovascular Diseases	Altered Intercellular Communication	There is accumulating evidence suggesting that inflammation is the bridging link between cardiovascular disease and metabolic syndrome.	22891522
Exanthema, Triggered by, Fever, CTCAE	Altered Intercellular Communication	Cryopyrin-associated periodic syndromes (CAPS) are characterized by apparently unprovoked attacks of fever, rashes, and musculoskeletal and sensorineural inflammation accompanied by high acute-phase reactants.	22891689
Nephritis, Lupus Erythematosus, Systemic	Altered Intercellular Communication	To assess whether urinary HMGB1 reflects renal inflammation we determined serum levels of HMGB1 simultaneously with its urinary levels in SLE patients with and without LN in comparison to healthy controls (HC).	22892043
Inflammation, Nephritis	Altered Intercellular Communication	These data suggest that urinary HMGB1 might reflect both local renal inflammation as well as systemic inflammation.	22892043
Inflammation, Cellulitis, Ulcer	Altered Intercellular Communication	Cellulitis is an acute inflammation of dermis and subcutaneous tissue, usually complicating wounds, ulcers, or dermatosis.	22892081
Vitreous inflammatory cells	Altered Intercellular Communication	Of 141 eyes, 115 (81.56%) showed vitreous inflammation.	22892153
Vitreous inflammatory cells	Altered Intercellular Communication	It was frequently bilateral with vitreous inflammation and characterized by multifocal lesions that were noncontiguous to the optic disc and showed serpiginoid spread.	22892153
Inflammation, Conductive hearing loss	Altered Intercellular Communication	Chronic obliterative otitis externa is a rare cause of conductive hearing loss, characterised by stenosis of the deep ear canal secondary to chronic inflammation.	22892176
Multiple Organ Failure, Inflammation, Leukocytosis, Fever, CTCAE, Specimen Source Codes - Abscess, Communicable Diseases, Single organ dysfunction, Hypotension, CTCAE, Systemic Inflammatory Response Syndrome, Empyema, Bacteremia, Cholangitis	Altered Intercellular Communication	Illness severity was classified as follows: none (no infection or inflammation), systemic inflammatory response syndrome (fever, leukocytosis), severe (abscess, cholangitis, empyema), or multi-organ dysfunction syndrome (bacteremia, hypotension, organ failure).	22892201
Hepatic inflammation	Altered Intercellular Communication	Follow-up liver biopsy after recovery showed improvement of hepatic inflammation and reduction of giant hepatocyte formation.	22892492
Mucous Membrane, Inflammation	Altered Intercellular Communication	and no differences in mucosal atrophy or the degree of chronic or acute inflammation were observed between groups 1, 2, and 3 (p>0.45).	22892912
Mucous Membrane, Inflammation, Metaplasia, Pouchitis	Altered Intercellular Communication	The degree of mucosal atrophy, the presence of colonic metaplasia, and the degree of acute or chronic inflammation do not appear to constitute risk factors for the development of pouchitis.	22892912
Inflammation, Intermittent Claudication	Altered Intercellular Communication	Impact of exercise training on inflammation and platelet activation in patients with intermittent claudication.	22893497
Neurogenic Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Our results suggest that smoking may worsen OSAS through exacerbation of upper airway collapse at the level of the uvula, and that histological changes of the uvular mucosa correlated with smoking might be due to increased CGRP-related neurogenic inflammation.	22893766
Inflammation, Pathologic Neovascularization	Altered Intercellular Communication	CLSM was able to visualize features of cutaneous wound repair in epidermal and superficial dermal wounds, including aspects of inflammation, neovascularisation, and tissue remodelling in vivo.	22894499
Inflammation, Carcinogenesis	Altered Intercellular Communication	Chronic inflammation is a driving force for gastric carcinogenesis.	22894650
Granulomatous inflammation, Carcinoma	Altered Intercellular Communication	CBP were more sensitive than smears for both diagnoses of carcinoma (p = 0.01) and granulomatous inflammation (p = 0.048).	22895864
Granulomatous inflammation, Carcinoma, Breast cancer, lobular	Altered Intercellular Communication	Conversely, LBC was less sensitive than smears for granulomatous inflammation (p = 0.004), but the difference was not significant for carcinoma (p = 0.42).	22895864
Granulomatous inflammation, Carcinoma	Altered Intercellular Communication	CBP, as a complement to smears, increases diagnostic yield and sensitivity for both diagnoses of carcinoma and granulomatous inflammation.	22895864
Cholangitis	Altered Intercellular Communication	In conclusion, eosinophilic cholangitis is an uncommon, inflammatory condition that needs to be considered as a differential diagnosis for periampullary malignancies.	22895905
Inflammation, Arthritis	Altered Intercellular Communication	Because increased numbers of CD4+IL-17+ T cells are seen in both diseases, these observations imply that there are different mechanisms underlying chronic inflammation in these 2 forms of inflammatory arthritis.	22896020
Inflammation	Altered Intercellular Communication	Increased synovial inflammation and tendon degeneration at the time of surgery are correlated with the failed healing of rotator cuff tendons.	22896627
Communicable Diseases, Unknown (origin) (qualifier value), Vasculitis, CTCAE, Vasculitis, Hypersensitivity	Altered Intercellular Communication	Vasculitis in childhood is a result of a spectrum of causes ranging from idiopathic conditions with primary vessel inflammation to syndromes after exposure to recognized antigenic triggers, such as infectious agents and drugs causing hypersensitivity reactions.	22897379
Brucellosis, Infectious agent, Vasculitis, CTCAE, Vasculitis, Hypersensitivity, Henoch-Schoenlein Purpura	Altered Intercellular Communication	brucellosis, trigger agent, Henoch-Schonlein purpura, vasculitis, infectious agents, drug, hypersensitivity reactions, primary vessel inflammation.	22897379
Inflammation, Septic Shock	Altered Intercellular Communication	Viscoelastic and aggregometric point-of-care testing in patients with septic shock - cross-links between inflammation and haemostasis.	22897591
Sepsis	Altered Intercellular Communication	In the pathogenesis of sepsis, inflammation-induced changes in coagulation play a pivotal role.	22897591
Neurogenic Inflammation, Hypersensitivity	Altered Intercellular Communication	These findings suggest that visceral hypersensitivity in NERD patients is involved in neurogenic inflammation showing the increase in both substance P release and NK1R expression, which may be associated with the activation of TRPV1 and PAR2.	22899239
Inflammation, Biliary calculi	Altered Intercellular Communication	Among the factors contributing to the gallstones formation an important role belongs to the inflammation.	22899412
Sample Size Calculation, Damage, Vascular Diseases	Altered Intercellular Communication	Systemic sclerosis (SSc) is characterized by multisystem organ inflammation, endothelial wall damage, and vasculopathy.	22899452
Inflammation, Lyme Disease	Altered Intercellular Communication	Here we have analyzed pooled cerebrospinal fluid (CSF) allowing a deep view into the proteome for patients diagnosed with early disseminated Lyme disease and CSF inflammation.	22900834
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	To reveal specific gene activation in nitric oxide (NO)-related inflammation we studied differential gene expression in inflammatory bowel disease (IBD).	22900953
Pain Distress Question, Inflammation, Fatigue	Altered Intercellular Communication	This suggests that in addition to treatments to reduce disease activity, strategies for alleviating fatigue in AS should focus on pain management techniques and actively treating inflammation.	22901458
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	We aimed to investigate whether recognized hormonal predictors of rheumatoid arthritis (RA) also influence the severity of RA.	22901865
Airway structure, Exacerbation of asthma, Asthma	Altered Intercellular Communication	Some patients with severe asthma have recurrent asthma exacerbations associated with eosinophilic airway inflammation.	22901886
Airway structure	Altered Intercellular Communication	Early studies suggest that inhibition of eosinophilic airway inflammation with mepolizumab-a monoclonal antibody against interleukin 5-is associated with a reduced risk of exacerbations.	22901886
Exacerbation of asthma, Inflammation	Altered Intercellular Communication	Eligible patients were aged 12-74 years, had a history of recurrent severe asthma exacerbations, and had signs of eosinophilic inflammation.	22901886
Inflammation, Atherosclerosis	Altered Intercellular Communication	Regression analyses demonstrated that the increased levels of CD4(+)CD28(null) T cells were positively correlated to serum levels of C-reactive protein, suggesting systemic inflammation and atherosclerosis.	22902395
Inflammation, Stomach Carcinoma, Colorectal Carcinoma	Altered Intercellular Communication	The CRC thermograms were compared to those of healthy individuals and patients with gastric cancer and non-cancerous soft tissue inflammation.	22903026
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The calorimetric profiles of blood plasma from CRC patients are found to be distinct from those of healthy individuals and those of patients with soft tissue, non-cancerous inflammation.	22903026
Delirium, Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Associations of markers of inflammation and coagulation with delirium during critical illness.	22903241
Delirium, Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	To assess the associations between a priori-selected markers of inflammation and coagulation and delirium during critical illness.	22903241
Delirium, Inflammation	Altered Intercellular Communication	Two markers of inflammation and one of coagulation were significantly associated with delirium.	22903241
Delirium, Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	These results suggest that specific aspects of inflammation and coagulation may play a role in the evolution of delirium during critical illness and that these markers should be examined in larger studies of ICU patients.	22903241
Meningitis	Altered Intercellular Communication	In the absence of meningeal inflammation, the CSF-to-serum albumin ratio (QAlbumin) was significantly higher in older patients than in younger ones.	22903361
Inflammation, FAM126A gene	Altered Intercellular Communication	Chronic inflammation contributes to the up-regulation of JNK activity in HCC.	22903704
Psoriasis, Dermatitis	Altered Intercellular Communication	Generalized pustular psoriasis (GPP) is a rare, potentially life threatening, and aggressive form of psoriasis, which is characterized by sudden onset with repeated episodic skin inflammation leading to pustule formation.	22903787
Cessation of life, Inflammation, Infectious Lung Disorder	Altered Intercellular Communication	Compared to ST228-I, ST22-IV had a significantly higher capacity to invade the A549 cells and a higher virulence in a murine model of acute lung infection causing severe inflammation and determining death in all the mice within 60 hours.	22905220
Inflammation, Damage	Altered Intercellular Communication	In individuals suffering from TA, arterial inflammation progresses to stenosis and/or occlusion, leading to organ damage and affecting survival.	22905864
ARCN1 gene, Inflammation	Altered Intercellular Communication	In COPD, serum biomarkers of inflammation and repair are distinctly associated with important clinical parameters and survival.	22906131
Inflammation	Altered Intercellular Communication	Alkaline phosphatase may serve as a biomarker and potential modulator of post-operative support and inflammation following cardiothoracic surgery in infants.	22906145
Inflammation, Metabolic Syndrome X, Atherosclerosis	Altered Intercellular Communication	Subjects with metabolic syndrome may have a closer relationship between inflammation and oxidative stress than subjects without metabolic syndrome, possibly reflecting their increased predisposition to atherosclerosis.	22906280
MS gene, Meningitis	Altered Intercellular Communication	Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis.	22907116
Inflammation, MS gene	Altered Intercellular Communication	Inflammation in the leptomeninges has been identified as a key feature of secondary progressive multiple sclerosis and may contribute to the extensive cortical pathology that accompanies progressive disease.	22907116
MS gene, Meningitis	Altered Intercellular Communication	Our aim was to investigate the extent of perivascular and meningeal inflammation in primary progressive multiple sclerosis in order to understand their contribution to the pathogenetic mechanisms associated with cortical pathology.	22907116
Neurites, Meningitis	Altered Intercellular Communication	A variable extent of meningeal immune cell infiltration was detected and more extensive demyelination and neurite loss in the cortical grey matter was found in cases exhibiting an increased level of meningeal inflammation.	22907116
MS gene, Meningitis	Altered Intercellular Communication	Our data suggest that generalized diffuse meningeal inflammation and the associated inflammatory milieu in the subarachnoid compartment plays a role in the pathogenesis of cortical grey matter lesions and an increased rate of clinical progression in primary progressive multiple sclerosis.	22907116
Inflammation, RTEL1 gene	Altered Intercellular Communication	Serum lipid levels may serve as biomarkers of inflammation associated with NHL risk.	22907421
Inflammation, atherosclerotic, Chronic Kidney Diseases	Altered Intercellular Communication	Cytotoxic CD4+CD28 null T lymphocytes, systemic inflammation and atherosclerotic risk in patients with chronic kidney disease.	22907478
Inflammation, Perforation (observation)	Altered Intercellular Communication	A CT scan revealed what appeared to be a small bone impacted in a diverticulum with evidence of recent inflammation and a sealed perforation.	22907849
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The TAM receptors (tyro3, axl and mer) and their ligands (vitamin K-dependent proteins-Gas6 and Protein S) are crucial modulators of inflammation, which may be relevant in chronic kidney disease (CKD).	22907951
Inflammation, Thrombosis, Cerebral Atherosclerosis, Chronic Kidney Diseases	Altered Intercellular Communication	Gas6 and axl have multiple roles in mediating vascular atherosclerosis and injury, thrombosis and inflammation, yet nothing is known about the Gas6-axl pathway in humans with CKD.	22907951
Inflammation, Vascular Diseases	Altered Intercellular Communication	Given the prevalence of chronic inflammation and vascular disease in this population, we measured TAM ligands in patients with various levels of renal function.	22907951
Refractory Cytopenia of Childhood, Demographics Domain, Obesity	Altered Intercellular Communication	Our curdata suggest that insulin resistance may be inversely associated with RCC risk, independently of obesity, DM, lifestyle and hormonal confounding variables.	22908063
Inflammation, Benign neoplasm of prostate	Altered Intercellular Communication	Multicentre study on the efficacy and tolerability of an extract of Serenoa repens in patients with chronic benign prostate conditions associated with inflammation.	22908779
Inflammation, Depression, CTCAE	Altered Intercellular Communication	These findings support a unidirectional relationship in which depression is a risk-factor for inflammation.	22910686
Inflammation, Atherosclerosis	Altered Intercellular Communication	These results demonstrate that IL-27 might regulate the network of immunity and inflammation in the pathogenesis of atherosclerosis.	22911112
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	In cirrhotic liver, most platelets were present in the sinusoidal space of the periportal area with inflammation, where HSCs expressing PDGF receptor-b were frequently observed.	22911171
Inflammation, Adult Non-Hodgkin Lymphoma	Altered Intercellular Communication	A two-stage evaluation of genetic variation in immune and inflammation genes with risk of non-Hodgkin lymphoma identifies new susceptibility locus in 6p21.3 region.	22911334
Inflammation, Lung Diseases, Obstructive	Altered Intercellular Communication	Heavy metal exposure may contribute to increased oxidative stress and inflammation in the lungs, resulting in tissue destruction manifesting clinically as obstructive lung disease (OLD).	22911427
Human immunodeficiency virus 2 (HIV-2), Inflammation	Altered Intercellular Communication	It is not known whether markers of inflammation such as high-sensitivity C-reactive protein (hsCRP), interleukin 6 (IL-6), and soluble CD14 (sCD14) may predict disease progression among HIV-2 patients.	22911639
Inflammation, Resolvin	Altered Intercellular Communication	Resolvins and protectins are families of local lipid mediators generated from the n-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) during self-limited resolution of inflammation.	22912397
glycation, vascular inflammations	Altered Intercellular Communication	Positive association between serum level of glyceraldehyde-derived advanced glycation end products and vascular inflammation evaluated by [(18)F]fluorodeoxyglucose positron emission tomography.	22912424
Inflammation, Salmonella	Altered Intercellular Communication	Oral administration of a combination of select lactic acid bacteria strains to reduce the Salmonella invasion and inflammation of broiler chicks.	22912447
Meningitis	Altered Intercellular Communication	The three tests did not yield any better results in the subsets of children with moderate or severe meningeal inflammation, nor in relation to any of the causative pathogens.	22914116
Coughing, Inflammation, Fever, CTCAE	Altered Intercellular Communication	She presented with severe cough and fever, and bronchoscopy revealed inflammation of the trachea.	22914966
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Our case highlights the potential interest of (18)F-FDG PET for tracheal involvement of UC, allowing a non-invasive assessment of local inflammation.	22914966
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	There is significant evidence for a central role of inflammation in the development of Alzheimer disease (AD).	22915243
Inflammation, Intestines	Altered Intercellular Communication	Retrospectively, image quality (including motion artifact and bowel distention) and enteric inflammation were assessed.	22915428
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumour necrosis factor inhibition plus methotrexate is believed to inhibit radiographic progression independent of inflammation.	22915617
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	We investigated whether rheumatoid arthritis (RA)-related autoantibodies were associated with systemic inflammation in a prospective cohort of first-degree relatives (FDRs) of RA probands, a population without RA but at increased risk for its future development.	22915618
Refractory anemias, Inflammation, Autoimmune Diseases	Altered Intercellular Communication	In first-degree relatives of patients with RA, RA-related autoimmunity is associated with inflammation, as evidenced by associations with multiple cytokines and chemokines.	22915618
Inflammation	Altered Intercellular Communication	To establish a relationship between visible third molars (M3s) and increased periodontal probing depths on teeth other than M3s and to examine the hypothesis that the presence of M3s and/or increased probing depths and local inflammation associated with M3s was associated with increased levels of serum inflammatory markers.	22916700
Inflammation	Altered Intercellular Communication	Retention of M3s in the presence of periodontal inflammation was associated with significant increases in the serum interleukin-6, soluble intracellular adhesion molecule-1, and C-reactive protein levels.	22916700
Inflammation, Sleep Disorders	Altered Intercellular Communication	Moderate exercise training may be a modality of non-pharmacological treatment for sleep disorders and inflammation.	22917967
Inflammation	Altered Intercellular Communication	To compare inflammation and lung function in swine workers after periods with and without respiratory protection during work.	22918380
Icterus, Inflammation, Neoplasms	Altered Intercellular Communication	To find a possible relationship between inflammation and CA19-9 tumor marker by analyzing data from patients with benign jaundice (BJ) and malignant jaundice (MJ).	22919247
Inflammation, Uveitis	Altered Intercellular Communication	After the second dose, there were 10 of them, while after the third dose of bevacizumab, there were 5 suffusions and 3 cases of inflammation of the anterior eye segment, anterior uveitis.	22919878
Arterial Stiffness, Inflammation, Refractory anemias	Altered Intercellular Communication	Arterial stiffness improved significantly in patients with early RA after effective control of inflammation.	22920235
glycation, Vascular Stiffness, Inflammation	Altered Intercellular Communication	Increase in sRAGE level was associated with a decrease in AIx, suggesting that sRAGE may play an important role in the ligand-soluble receptor for advanced glycation end product interaction propagated inflammation and vascular stiffness in these patients.	22920235
Dermatitis, Atopic, Inflammation, Psoriasis	Altered Intercellular Communication	Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation.	22920495
Lesion, Inflammation	Altered Intercellular Communication	Acute AD lesions are associated with T(H)2 and eosinophilic inflammation, whereas psoriatic lesions are associated with T(H)1/T(H)17 and neutrophilic inflammation.	22920495
Inflammation, allergic inflammation, Data types - Address, GDC Comorbidity Terminology	Altered Intercellular Communication	These data are evidence that neutrophilic inflammation is a feature of lesional AD pathology comorbid with allergic inflammation.	22920495
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Skin biopsies revealed lobular inflammation of the subcutaneous fat with vasculitis.	22920648
Inflammation, Bacterial Infections	Altered Intercellular Communication	We hypothesize that BCG-induced inflammation may eradicate bacterial infection.	22921719
Inflammation, Metaplasia, Necrosis	Altered Intercellular Communication	Necrotic salivary glands and inflammation were universal microscopic features; ductal metaplasia was present in only 1 case.	22921832
Pancreatic stone, Arteritis	Altered Intercellular Communication	Pancreatic stone protein/regenerating protein (PSP/reg) serum levels are supposed to be increased in bacterial inflammation.	22922487
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	There is growing consensus in the literature that inflammation plays a significant role in the pathophysiology of Alzheimer's disease (AD).	22922667
Inflammation, Data types - Address	Altered Intercellular Communication	The results of this study suggested that inflammation plays a role in the pathogenesis of AD.	22922667
Weight Gain, Inflammation, Cardiac dysfunction	Altered Intercellular Communication	Supplementary ultrafiltration may improve inflammation and cardiac dysfunction in patients with high interdialytic weight gain.	22922813
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Epidemiologic and experimental evidences support the concept that inflammation promotes the development and progression of cancers.	22923190
Renal Insufficiency, Hypertension, Renovascular, Right Ventricular Hypertrophy	Altered Intercellular Communication	Renovascular hypertension (RVH) is characterized by chronic inflammation of the stenotic kidney and progressive renal dysfunction.	22923545
Inflammation, Right Ventricular Hypertrophy, Ischemia	Altered Intercellular Communication	Chronic RVH is associated with elevated NGAL levels, likely due to ongoing kidney and systemic inflammation and ischemia.	22923545
Inflammation, Right Ventricular Hypertrophy	Altered Intercellular Communication	These findings may also imply the occurrence of the inflammation process in chronic RVH, which might contribute to the poorer outcomes of RVH compared with EH patients.	22923545
Acute Kidney Injury, CTCAE, Ischemia	Altered Intercellular Communication	Neutrophil gelatinase-associated lipocalin (NGAL), an acute phase protein induced in inflammatory conditions and ischemia, is a novel biomarker for acute kidney injury.	22923545
Alveolar damage, Disability Assessment for Dementia Questionnaire	Altered Intercellular Communication	Double immunohistochemistry of CMV antigen and cellular markers showed that epithelial tropism was associated with a diffuse alveolar damage (DAD) pattern (CMVp-DAD) while stromal tropism was associated with a predominantly interstitial inflammation/fibrosis (IIF) (CMVp-IIF) or a combination of DAD and IIF (CMVp-complex).	22924849
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	There is an accumulating body of evidence indicating a strong association between inflammation and the pathogenesis of atrial fibrillation (AF).	22924939
Asthma, Bronchial Hyperreactivity, Bronchitis	Altered Intercellular Communication	Bronchial inflammation and hyperresponsiveness in well controlled asthma.	22925318
Bronchitis	Altered Intercellular Communication	Little research has been devoted to the characteristics of bronchial inflammation in patients with stable, well controlled asthma.	22925318
Bronchitis	Altered Intercellular Communication	A total of 59 patients had persistent bronchial inflammation: 28 cases were considered eosinophilic, 28 neutrophilic, and 3 mixed.	22925318
Inflammation	Altered Intercellular Communication	The geometric mean (95% CI) of the methacholine PC20 was 1.74 mg/mL (1.04-2.93) in patients with eosinophilic inflammation and 4.14 mg/mL (2.5-6.84) in those with neutrophilic inflammation (P = 0.03).	22925318
Inflammation, Bronchial Hyperreactivity	Altered Intercellular Communication	Inflammation and bronchial hyperresponsiveness persist in most patients with well controlled asthma.	22925318
Inflammation, Asthma, Bronchitis	Altered Intercellular Communication	The study demonstrates that eosinophilic or neutrophilic inflammation persisted in most well controlled asthma patients despite the fact that their condition was controlled and therefore, measurement of bronchial inflammation seems essential to achieve proper asthma control.	22925318
allergic inflammation	Altered Intercellular Communication	Hematopoietic progenitor cells, especially those committed to the Eo/B lineage, are known to contribute to allergic inflammation.	22925320
Inflammation	Altered Intercellular Communication	In vitro and animal studies suggest that vitamin D may play a crucial role in immune activation and inflammation.	22925537
Heart Diseases, Inflammation	Altered Intercellular Communication	This system is expressed also in adipose tissue, which could thus be involved in cardiac disorders through modulation of metabolically triggered inflammation.	22926037
Depression, CTCAE	Altered Intercellular Communication	These prospective data support the role of fatty acid status in depression vulnerability and indicate a potential role for omega-3 fatty acids in the prevention of inflammation-induced depression.	22926083
Inflammation, Panophthalmitis	Altered Intercellular Communication	Panophthalmitis is an acute, purulent inflammation of the eyeball that involves all its structures and extends into the orbit.	22926396
Inflammation	Altered Intercellular Communication	A novel sinonasal endoscopy scoring system: the discharge, inflammation, and polyps/edema (DIP) score.	22927217
Mesenteric Panniculitis	Altered Intercellular Communication	First described in 1924, mesenteric panniculitis is a benign inflammatory condition of the bowel mesentery.	22927274
Neuroblastoma, Neoplasms	Altered Intercellular Communication	Metastatic neuroblastomas had higher infiltration of TAMs than locoregional tumors, and metastatic tumors diagnosed in patients at age >= 18 months had higher expression of inflammation-related genes than those in patients diagnosed at age < 18 months.	22927533
Communicable Diseases, Inflammation, Neoplasms	Altered Intercellular Communication	Definite diagnoses were categorized into four groups: inflammation (84.4%); infection (5.8%); tumor (6.5%); and nonspecific (3.2%).	22928517
Inflammation, Erythema Nodosum	Altered Intercellular Communication	The most common cause in the inflammation group was erythema nodosum.	22928517
Infection, Neoplasms	Altered Intercellular Communication	Various inflammatory conditions, infections, and tumors can present as tender cutaneous nodules of the legs.	22928517
Stomach Diseases	Altered Intercellular Communication	Reactive gastropathy is associated with inflammatory conditions throughout the gastrointestinal tract.	22928604
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	We show that genetic variation in FXR is associated with IBD, further emphasizing the link between bile acid signaling and intestinal inflammation.	22929053
Inflammation, Depression, CTCAE	Altered Intercellular Communication	IDO-induced alterations in serotonergic function may offer one biologic explanation to the well-established associations between inflammation and depression.	22929065
Communicable Diseases, Inflammation	Altered Intercellular Communication	No evidence of infection or inflammation was detected.	22929158
Communicable Diseases, Inflammation	Altered Intercellular Communication	A puzzling case of increased serum clozapine levels in a patient with inflammation and infection.	22929408
Communicable Diseases, Inflammation	Altered Intercellular Communication	First, a downregulation of CYP enzyme activities, which primarily seems to be mediated by interleukin-6, takes place during infection and inflammation.	22929408
Communicable Diseases, Inflammation	Altered Intercellular Communication	Second, the concentration of the acute phase protein a1-acid glycoprotein (AGP; orosomucoid) increases during infection and inflammation.	22929408
Inflammation	Altered Intercellular Communication	These observations suggest that lubricin is able to bind to PMN via an L-selectin-dependent and -independent manner and may play a role in PMN-mediated inflammation.	22930755
Renal Insufficiency, Inflammation, Cardiac dysfunction	Altered Intercellular Communication	To analyse the relationship between objectively measured daily walking duration and cardiovascular biomarkers of inflammation, cardiac dysfunction and renal impairment.	22930799
Inflammation, Degenerative disorder, HIV Infections	Altered Intercellular Communication	In addition to residual HIV infection, immune activation (leading to immunodeficiency) and some antiretrovirals might contribute to low-grade systemic inflammation that could drive tissue senescence and provoke degenerative and proliferative disorders.	22930865
Coronary microvascular dysfunction, Inflammation, Pentalogy of Cantrell, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Subclinical coronary microvascular dysfunction can occur in SLE patients without traditional cardiovascular risk factors, probably associated with underlying inflammation and impairment of TAS.	22931164
Inflammation, Pancreatitis	Altered Intercellular Communication	Tumor-associated macrophages can be affected by cancer-related inflammation and pancreatitis and interact with important invasive behavior in a recurrent manner in pancreatic IDC.	22931216
Abnormal joint morphology, Coxitis	Altered Intercellular Communication	US examination found signs of hip joint abnormalities in 42% of the patients; US changes indicative of hip joint inflammation and damage were detected respectively in 24% and 32% of the cases.	22931581
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	[Structural and functional changes of the carotid artery and their relationship with subclinical inflammation in patients with H-type hypertension].	22931616
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	To investigate the changes in the structure and function of the carotid artery and their relationship with subclinical inflammation in patients with H-type hypertension.	22931616
Inflammation, Hyperhomocysteinemia	Altered Intercellular Communication	These changes might be attributed to the synergism of subclinical inflammation and hyperhomocysteinemia, for which active intervention may prove beneficial.	22931616
Inflammation, Atherosclerosis	Altered Intercellular Communication	Transforming growth factor beta1 (TGFb1) is a multifunctional cytokine involved in inflammation and pathogenesis of atherosclerosis.	22931704
Inflammation, diabetic	Altered Intercellular Communication	We present an atypical clinical course of CST in a 61-year-old male diabetic patient caused by a distant focus of inflammation.	22931741
Airway structure, Chronic cough	Altered Intercellular Communication	The method and the preliminary data may be used for research, diagnosis and treatment of patients with chronic cough and airway inflammation.	22932015
Mucous Membrane, Inflammation	Altered Intercellular Communication	For histological improvement, gefarnate showed both effective in decreasing mucosal chronic inflammation (57.7% vs. 24.8%, P < 0.001, intension-to-treat) and active inflammation (36.4% vs. 23.1%, P < 0.05, intension-to-treat) than the control.	22932084
Inflammation, Chronic erosive gastritis	Altered Intercellular Communication	Gefarnate demonstrates an effective outcome on the mucosal inflammation in patients with chronic erosive gastritis.	22932084
Pulmonary Emphysema, Pneumonitis, Pulmonary Fibrosis	Altered Intercellular Communication	Characteristics of pulmonary inflammation in combined pulmonary fibrosis and emphysema.	22932172
Pneumonitis	Altered Intercellular Communication	However, the pulmonary inflammation characteristics of CPFE are not well known, and the differences between CPFE and the other two diseases with regards to pulmonary inflammation need to be explored.	22932172
Airway structure, Idiopathic Pulmonary Fibrosis, Pneumonitis	Altered Intercellular Communication	The pulmonary inflammation of CPFE group is more similar to IPF group, while the distal airway inflammation is more significant in CPFE and IPF groups than in EA group.	22932172
Pathology	Altered Intercellular Communication	Considering these low concentrations proved effective in vitro, translation of these data to human research on inflammation-related pathologies can be envisaged.	22933405
Orbital Pseudotumor	Altered Intercellular Communication	A 55-year-old woman with orbital inflammation.	22933406
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Elderly- versus younger-onset rheumatoid arthritis: higher levels of ultrasound-detected inflammation despite comparable clinical disease activity.	22933417
Inflammation, Rheumatoid Arthritis, ER-overload response	Altered Intercellular Communication	To compare ultrasound-verified joint inflammation between elderly-onset rheumatoid arthritis (EORA) and younger-onset rheumatoid arthritis (YORA) patients.	22933417
Inflammation	Altered Intercellular Communication	The sonographic pattern of joint involvement was similar in both groups, with active inflammation most commonly presenting at the wrists.	22933417
prostatitis	Altered Intercellular Communication	[Aggressiveness and extent of prostatic inflammation relates with serum PSA levels in type IV prostatitis].	22934516
prostatitis	Altered Intercellular Communication	To investigate the relationship of the histopathologic grade and extent of prostatic inflammation with the level of serum PSA in patients with type IV prostatitis.	22934516
Aggressive behavior, prostatitis	Altered Intercellular Communication	We evaluated the relationship between prostatic inflammation and serum PSA levels based on the three-grade pathohistologic criteria for the extent, location and aggressiveness of prostatic inflammation.	22934516
Inflammation	Altered Intercellular Communication	Regarding the location of inflammation, 19 cases were grade I, 17 were grade II and 10 were grade II, with no significant differences in tPSA, fPSA and %fPSA among the three grades (P > 0.05).	22934516
Inflammation, Aggressive behavior	Altered Intercellular Communication	As for the aggressiveness of inflammation, 32 cases were grade I (tPSA: [8.37 +/- 4.07] microg/L; fPSA: [1.76 +/- 0.93] microg/L; PSAD: 0.14 +/- 0.11), 10 were grade II (tPSA: [13.30 +/- 5.69] microg/L; fPSA: [3.27 +/- 2.21] microg/L ; PSAD: 0.25 +/- 0.06) and 4 were grade III (tPSA: [21.05 +/- 7.58] microg/L; fPSA: [3.19 +/- 1.13] microg/L; PSAD: 0.42 +/- 0.19), with statistically significant differences among the three grades in the levels of tPSA (P = 0.002), fPSA (P = 0.024) and PSAD (P < 0.001).	22934516
Aggressive behavior, prostatitis	Altered Intercellular Communication	The aggressiveness and extent of prostatic inflammation in asymptomatic prostatitis patients are significantly correlated with the level of serum PSA, which may help pathologists to avoid unnecessary repeated biopsies for patients with high-grade prostatitis.	22934516
CLU protein, human, Ischemia, Inflammation	Altered Intercellular Communication	Chronic critical limb ischemia (CLI) is a severe condition of hypo-perfusion of lower limbs, which is associated with inflammation and a pro-coagulative state.	22936457
Inflammation, Calcinosis	Altered Intercellular Communication	In 4 cases calcification and in 19 cases inflammation was observed.	22936554
Exacerbation	Altered Intercellular Communication	PR3 activity was greater during exacerbations than in the stable state (p=0.037) and correlated with markers of neutrophilic inflammation.	22936713
Inflammation, Arthritis, Infectious	Altered Intercellular Communication	The joint fluid was inflammatory, with no crystals, and laboratory tests showed marked inflammation leading to antibiotic treatment for suspected septic arthritis.	22937184
Inflammation, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8	Altered Intercellular Communication	Western blot analyses from T1D SAMP8 mice showed elevated amyloid precursor protein processing and protein glycation along with increased inflammation.	22938075
Inflammation, Phimosis	Altered Intercellular Communication	Non HPV related risk factors are lack of circumcision, phimosis, chronic inflammation, and smoking.	22939906
Inflammation, Neoplasms	Altered Intercellular Communication	Prognostic importance of markers for inflammation, angiogenesis and apoptosis in high grade glial tumors during temozolomide and radiotherapy.	22940539
Glioma, Inflammation, Carcinogenesis	Altered Intercellular Communication	Angiogenesis, inflammation and apoptosis have an important place in the carcinogenesis of high-grade gliomas (HGG).	22940539
Aphthous Stomatitis, Inflammation, Fever, CTCAE, Tonsillitis	Altered Intercellular Communication	A 10-year-old boy presented with periodic fever, exudative tonsillitis, oral aphthous ulcer, and cervical lymph node inflammation.	22940910
Inflammation, Brain Injuries	Altered Intercellular Communication	Inflammation following ischemic brain injury is correlated with adverse outcome.	22942727
Autoimmune Diseases, Inflammation, Thromboangiitis Obliterans	Altered Intercellular Communication	Activation of cytokines corroborate with development of inflammation and autoimmunity in thromboangiitis obliterans patients.	22943198
Vasculitis	Altered Intercellular Communication	The immune system seems to play a critical role in the aetiology of TAO; however, knowledge of the aspects involved in the progression of vascular tissue inflammation and, consequently, the evolution of this disease is still limited.	22943198
Malignant neoplasm of urinary bladder, Inflammation, Hematuria, CTCAE, Benign Prostatic Hyperplasia	Altered Intercellular Communication	Among them, 54 were diagnosed as bladder cancer, and the remaining 196, which consisted of healthy individuals and patients with hematuria, inflammation/infection, or benign prostate hyperplasia, were assigned to the control group.	22944145
Pain Distress Question, Inflammation, Edema, Lipodermatosclerosis, Pigmentation	Altered Intercellular Communication	The analysis of clinical severity scores (pain, edema, pigmentation, lipodermatosclerosis, and inflammation) revealed significant improvement when comparing pre- and post-treatment results.	22944569
Intradermal Route of Drug Administration	Altered Intercellular Communication	ID is more common in OW children; this may be due to adiposity-related inflammation reducing iron absorption.	22945607
Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation was inactive during the study period.	22946454
Intraocular inflammation, Low Vision	Altered Intercellular Communication	In well-controlled intraocular inflammation, increase in the ERM thickness does not lead to loss of vision in a 2-year FU period.	22946454
vascular inflammations, Hypertension, CTCAE	Altered Intercellular Communication	The hallmark of vascular inflammation is the recruitment of circulating leucocytes, primarily monocytes, macrophages and T lymphocytes, into the vascular wall; however, the link between monocyte/macrophage activation and hypertension has not been established as yet.	22946776
ARCN1 gene, Inflammation, Impaired	Altered Intercellular Communication	We studied heart rate variability (HRV) in COPD patients at rest and during the 6-minute Walk Test (6mWT) and the association with lung function impairment taking into account systemic inflammation.	22946790
ARCN1 gene, Inflammation, Impaired	Altered Intercellular Communication	At rest and during submaximal exercise, COPD patients with moderate and severe disease had an abnormal cardiac autonomic modulation which was related to both systemic inflammation and lung function impairment.	22946790
Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is a chronic inflammatory condition that affects the arterial wall.	22947906
Inflammation, HIV-1	Altered Intercellular Communication	Chronic inflammation from persistent immune activation could contribute to this poor response, resulting in HIV-1 disease progression and the development of some non-HIV-1 comorbidities.	22948290
Waldenstrom Macroglobulinemia, Pleurisy	Altered Intercellular Communication	Pleural biopsy performed during the decortication procedure revealed fibrinous pleuritis with lymphoplasmacytic inflammation including IgG4-positive plasma cells.	22948582
Inflammation, Duodenitis	Altered Intercellular Communication	Of the 93 patients with endoscopic features of duodenitis an increase in histological markers of inflammation was found in 75 (81%).	22949941
Inflammation, Musculoskeletal Pain, Arthritis, Infectious	Altered Intercellular Communication	In particular, minocycline-induced pigmentation of periarticular bone may be accelerated by inflammation due to rheumatic or pyogenic arthritis.	22949948
Neurodegenerative Disorders, "Alzheimers Disease", Data types - Address, Inflammation	Altered Intercellular Communication	Alzheimer disease (AD) is the most common neurodegenerative disease, and inflammation has been associated with the pathogenesis of AD.	22950423
Airway structure	Altered Intercellular Communication	The use of bronchodilators (BD), and inhaled corticosteroids (IC) have been suggested for the management of airway inflammation in CF.	22950544
Inflammation	Altered Intercellular Communication	Antiretroviral agents and chronic inflammation may adversely affect glycemic control.	22951636
Rhinosinusitis, Acute sinusitis	Altered Intercellular Communication	10% of all cases with chronic inflammation of paranasal sinuses, were diagnosed with fungal rhinosinusitis.	22952104
Inflammation, Subarachnoid Hemorrhage, Cerebral Ischemia	Altered Intercellular Communication	Inflammation as a predictor for delayed cerebral ischemia after aneurysmal subarachnoid haemorrhage.	22952245
Inflammation, Compression neuropathy of ilioinguinal nerve	Altered Intercellular Communication	The results suggest that symptoms are related to tendon inflammation and ilioinguinal nerve compression, and can be abolished with pharmacological or radiofrequency treatment, without the need for surgery.	22952407
Inflammation, Metastatic hepatocellular carcinoma	Altered Intercellular Communication	Mesenchymal stem cells in inflammation microenvironment accelerates hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition.	22952657
Inflammation, Tissue injury	Altered Intercellular Communication	In response to inflammation, mesenchymal stem cells (MSCs) are known to migrate to tissue injury sites to participate in immune modulation, tissue remodeling and wound healing.	22952657
Inflammation, Liver carcinoma, Neoplasm Metastasis, FAM126A gene	Altered Intercellular Communication	Here, we demonstrate that MSCs promote human hepatocellular carcinoma (HCC) metastasis under the influence of inflammation.	22952657
Pneumonitis	Altered Intercellular Communication	LPS-induced lung inflammation in marmoset monkeys - an acute model for anti-inflammatory drug testing.	22952743
Inflammation, Inflammatory disorder	Altered Intercellular Communication	In the current study, a tiered acute lipopolysaccharide (LPS)-induced inflammation model was established in marmoset monkeys (Callithrix jacchus) to reflect crucial features of inflammatory lung diseases.	22952743
Inflammation, Ischemia, Cessation of life, Damage, Candidal endocarditis	Altered Intercellular Communication	Candidal endocarditis complications include heart damage, inflammation, and emboli with resulting ischemia and tissue death.	22953512
Inflammation, Eczema	Altered Intercellular Communication	It is characterized by chronic inflammation, eczema, and increasing intestinal permeability.	22955359
Sjogrens Syndrome", Inflammation, Autoimmune Diseases	Altered Intercellular Communication	Sjogren syndrome is a common, chronic autoimmune disease that typically produces inflammation and poor function of the salivary and lacrimal glands.	22955477
Inflammation	Altered Intercellular Communication	Diagnostic tests were significant for marked systemic inflammation.	22955481
Inflammation, atherosclerotic	Altered Intercellular Communication	Macrophages in atherosclerotic plaques secrete YKL-40, a new biomarker of acute and chronic inflammation in patients with stable CAD.	22955689
Inflammation	Altered Intercellular Communication	We hypothesized that YKL-40 may be a specific marker reflecting the burden of localized inflammation in myocardium and a predictor in patients with STEMI.	22955689
Inflammation	Altered Intercellular Communication	Interleukin-17A plays a role in tissue inflammation by inducing release of proinflammatory and neutrophil-mobilizing cytokines.	22955700
Inflammation, Blood Clot, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Local inflammation is associated with aortic thrombus formation in abdominal aortic aneurysms.	22955940
Inflammation, Observation Method - Coagulation, Blood Clot	Altered Intercellular Communication	Interplay between coagulation and inflammation, characterised by leukocyte infiltration and cytokine production, has been implicated in AAA thrombus formation.	22955940
Inflammation	Altered Intercellular Communication	Increased stromal chronic inflammation correlated with longer disease-free interval (r(2) = 0.38).	22956472
Inflammation	Altered Intercellular Communication	Increased stromal chronic inflammation correlates with improved disease outcome.	22956472
Inflammation, Craniosynostosis	Altered Intercellular Communication	In CRS patients, expression of 471 genes, including inflammation and oxidative stress related genes was different from healthy controls.	22957013
Inflammation, Craniosynostosis, Anemia	Altered Intercellular Communication	In stable, treated CRS patients with mild anemia, monocyte transcriptomes were modestly altered, and indicated imprints of inflammation and oxidative stress.	22957013
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	ESAM correlates with diabetes duration and control, inflammation and VEGF-A in patients with diabetes, but not in controls.	22957687
Inflammation, Prostate carcinoma, Neoplasms	Altered Intercellular Communication	Recent evidence suggests that CXCL16, a novel chemokine, is overexpressed in inflammation-associated tumors and mediates pro-tumorigenic effects of inflammation in prostate cancer.	22958742
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	While viscosity correlated with parameters of vascular inflammation, it showed no relationship with the presence and severity of central atherosclerosis.	22960302
Inflammation	Altered Intercellular Communication	We hypothesized that markers of MT, soluble CD14 (sCD14) and lipopolysaccharide (LPS) binding protein (LBP), may be a source of chronic inflammation in older persons and be associated with poorer physical function.	22960476
Inflammation	Altered Intercellular Communication	In healthy older individuals, LBP, a surrogate marker of MT, is associated with worse physical function and inflammation.	22960476
Inflammation, BDI - Functional Impairment	Altered Intercellular Communication	Additional study is needed to determine whether MT is a marker for or a cause of inflammation and the associated functional impairments.	22960476
Inflammation, Werner Syndrome	Altered Intercellular Communication	Aging-associated inflammation in healthy Japanese individuals and patients with Werner syndrome.	22960593
Inflammation, Williams Syndrome	Altered Intercellular Communication	Both normal aging and WS were associated with minor inflammation that can be evaluated by serum hsCRP.	22960593
Werner Syndrome, Williams Syndrome	Altered Intercellular Communication	To study the inflammatory condition associated with normal human aging, highly sensitive CRP (hsCRP) was examined in the sera collected from 217 healthy Japanese individuals aged between 1 and 100years and 41 mutation-proven Japanese Werner syndrome (WS) patients.	22960593
Fibrous, Fibrosis Assessment, Perifolliculitis	Altered Intercellular Communication	The most common follicular-related changes were infundibular dilatation (87%) followed by perifollicular fibrosis (77%), perifollicular lymphocytic inflammation (68%), thinning of the follicular infundibulum (55%), and fibrous tracts (28%).	22960818
Inflammation	Altered Intercellular Communication	Since inflammation is known to modulate the microcirculation, we investigated the hypothesis that changes in the local perfusion might be one of the earliest signs of lesion development.	22961546
Inflammation, Coronary Arteriosclerosis, Myocardial Ischemia, Atherosclerosis	Altered Intercellular Communication	Systemic inflammation increases the risk of atherosclerosis and ischaemic heart disease (IHD).	22961677
Inflammatory Bowel Diseases, Inflammation, Myocardial Ischemia	Altered Intercellular Communication	The increased long-term risk of IHD in IBD may be related to chronic inflammation, and interventions reducing the inflammatory burden may attenuate this risk.	22961677
Presenile dementia, vascular inflammations, Ischemic stroke	Altered Intercellular Communication	Lipoprotein phospholipase-A2 (Lp-PLA2) is a circulating enzyme marker of vascular inflammation associated with risk of ischemic stroke and dementia.	22961963
Inflammation, Myocarditis, CTCAE 5.0, Infiltrative Tumor Margin	Altered Intercellular Communication	CMR imaging showed patterns of late gadolinium enhancement supportive of infiltrative disease or inflammation in 6 patients with EMB-proven definite (n=3) or borderline (n=3) myocarditis, but failed to do so in two other patients with borderline and two with resolving myocarditis.	22963032
Inflammation	Altered Intercellular Communication	Together with the early involvement of neutrophils and the destruction of the basal lamina, we suggest that the binding of autoantibodies to the nonhemidesmosomal lamina lucida may induce inflammation with neutrophils, resulting in blister formation.	22963596
vascular inflammations, Mucocutaneous Lymph Node Syndrome	Altered Intercellular Communication	The pathophysiology of Kawasaki syndrome presumably involves vascular inflammation, causing plasma leakage from systemic microvessels.	22964445
Inflammation, Idiopathic Inflammatory Myopathies	Altered Intercellular Communication	Toll-like receptors promote inflammation in idiopathic inflammatory myopathies.	22964787
Stomach Carcinoma	Altered Intercellular Communication	Comparison of two inflammation-based prognostic scores in patients with unresectable advanced gastric cancer.	22964877
Stomach Carcinoma, Atypical Glandular Cell	Altered Intercellular Communication	The objective of this study was to compare the usefulness of two inflammation-based prognostic scores, neutrophil to lymphocyte ratio (NLR) and modified Glasgow Prognostic Score (mGPS), assessed at diagnosis in stage IV advanced gastric cancer (AGC).	22964877
Inflammation, Refractory anemias, Degenerative polyarthritis, Rheumatoid Arthritis, Haiti, Hypertension, CTCAE	Altered Intercellular Communication	In this study, we compare the prevalence of arterial hypertension (HT) in rheumatoid arthritis (RA) and osteoarthritis (OA) patients, exposed to high- and low-grade chronic inflammation, respectively, to assess the possible association between chronic inflammation and HT.	22965673
Inflammation, Sinusitis	Altered Intercellular Communication	No disease was identified on 25.1% of pre-SCT CT scans, mild sinus inflammation was identified on 60.7% of scans, 11.3% had moderate inflammation, and 2.9% had severe inflammation.	22965703
Inflammation, Psoriasis, Chronic disease	Altered Intercellular Communication	Psoriasis is a chronic disease characterized by inflammation of the skin.	22965812
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Both LAE and SAE, independent of traditional risk factors and inflammation, are associated with subclinical coronary atherosclerosis.	22965846
Inflammation, Aortic valve calcification, Chronic inflammatory disorder	Altered Intercellular Communication	Calcific aortic stenosis is a chronic inflammatory disease, and aortic valve interstitial cells (AVIC) play an important role in valvular inflammation.	22965987
Inflammation, Specimen Source Codes - Abscess	Altered Intercellular Communication	CT findings were: (i) nondiagnostic; (ii) moderate (peri-colic inflammation); and (iii) severe (abscess and/or extra-luminal gas and/or contrast).	22967027
Gastric mucosa, Gastritis	Altered Intercellular Communication	Increasing severity of gastric inflammation was observed in gastric mucosa infected with strains carrying RFLP-2, 3, 4, 5, and 6 (p = .037).	22967117
Intestinal metaplasia, Inflammation, Gland	Altered Intercellular Communication	All the scores for chronic inflammation, neutrophil activity, glandular atrophy, and intestinal metaplasia were significantly lower in H. pylori-positive Bangladeshis than in H. pylori-positive Japanese.	22967124
Inflammation, Thrombosis, myocardial injury	Altered Intercellular Communication	Myocardial injury was produced in CS-exposed marginal vitamin C-deficient guinea pigs as evidenced by release of cardiac Troponin-T and I in the serum, oxidative stress, inflammation, apoptosis, thrombosis and collagen deposition in the myocardium.	22970172
Inflammation, Carcinogenesis	Altered Intercellular Communication	We hypothesized that inflammation modulates carcinogenesis through senescence and DNA damage response (DDR).	22970173
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	Efficacy and safety of indomethacin 0.1% eye drops compared with ketorolac 0.5% eye drops in the management of ocular inflammation after cataract surgery.	22970738
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	To determine whether indomethacin 0.1% eye drops are at least as effective as ketorolac 0.5% eye drops in treating ocular inflammation following cataract surgery.	22970738
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	Indomethacin 0.1% was at least as effective as ketorolac 0.5% at Day 1 and more effective than ketorolac 0.5% at Day 7 in treating ocular inflammation after uncomplicated cataract surgery.	22970738
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The neutrophil-to-lymphocyte ratio (NLR), an inflammation marker, is prognostic in several cancers.	22971522
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Preoperative elevation of markers of systemic inflammation is associated with a poor outcome in several cancers.	22972002
PEA15 wt Allele	Altered Intercellular Communication	The corneal epithelial healing efficacy of PRP was compared with that of AS in patients with PED induced by post-infectious inflammation.	22972393
Synovitis	Altered Intercellular Communication	Disease-specific and inflammation-independent stromal alterations in spondylarthritis synovitis.	22972410
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The molecular processes driving the distinct patterns of synovial inflammation and tissue remodeling in spondylarthritis (SpA) as compared to rheumatoid arthritis (RA) remain largely unknown.	22972410
Inflammation	Altered Intercellular Communication	The fact that this stromal alteration appeared not to be downstream of local inflammation warrants further analysis of its functional role in the pathogenesis of the disease.	22972410
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Is inflammation a new risk factor of depression in haemodialysis patients?	22972567
Inflammation, Depression, CTCAE, Bipolar Disorder	Altered Intercellular Communication	The aim of the study was to estimate the prevalence of depressive symptoms in haemodialyzed patients in Upper Silesia region of Poland and the possible role of inflammation in depression development.	22972567
Inflammation, Depression, CTCAE	Altered Intercellular Communication	(2) Catheter placement and inflammation seem to play an important role in the pathogenesis of depression in haemodialysis patients.	22972567
Acute inflammation	Altered Intercellular Communication	RAM-CLs were found in a subset of patients with MS who also have more active WM inflammation and a less favorable disease course.	22972651
Coinfection, Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Persistent mucosal inflammation and microbial infection are characteristics of chronic rhinosinusitis (CRS).	22972842
Hepatitis	Altered Intercellular Communication	There was a close temporal correlation between IL-10 levels and fluctuations in viral load or liver inflammation.	22972930
Inflammation, Metabolic Syndrome X, Erectile dysfunction	Altered Intercellular Communication	Metabolic syndrome, hormone levels, and inflammation in patients with erectile dysfunction.	22973171
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Chronic inflammation found in patients with ED might explain the association between ED and metabolic syndrome.	22973171
Inflammation, Metabolic Syndrome X, Erectile dysfunction	Altered Intercellular Communication	Metabolic syndrome, hormone levels, and inflammation in patients with erectile dysfunction.	22973171
Inflammation, Lichenoid	Altered Intercellular Communication	Comparing by response, normalization of stratum corneum and epidermis, orthohyperkeratosis, decrease in linearly arranged cells, the lichenoid/patchy lichenoid infiltration, the loss of inflammation were statistically significant in responders group.	22973172
Malaria, Falciparum, Inflammation, Plasmodium vivax	Altered Intercellular Communication	Although Plasmodium vivax usually causes a relatively benign disease, this parasite has been suggested to elicit more host inflammation per parasitized red blood cell than P. falciparum.	22973442
Malaria, Falciparum, Infection, Tissue damage	Altered Intercellular Communication	Controlling fast-multiplying P. falciparum blood stages requires a strong inflammatory response to prevent fulminant infections, while reducing inflammation-related tissue damage with early regulatory cytokine responses may be a more cost-effective strategy in infections with the less virulent P. vivax parasite.	22973442
Sepsis, Inflammation	Altered Intercellular Communication	Alterations of leptin in the course of inflammation and severe sepsis.	22973876
Interstitial Cystitis	Altered Intercellular Communication	Interstitial Cystitis (IC) is a chronic inflammatory condition of the bladder with unknown etiology.	22974186
Fibrosis Assessment, Myocarditis	Altered Intercellular Communication	Putative mediators of myocardial inflammation and fibrosis, including macrophage migration inhibitory factor (MIF), were also measured.	22974800
Inflammation, Atherosclerosis	Altered Intercellular Communication	Effects of p38 mitogen-activated protein kinase inhibition on vascular and systemic inflammation in patients with atherosclerosis.	22974804
Central Nervous System	Altered Intercellular Communication	Here, we have explored Purkinje cell fusion and heterokaryon formation in the human brain and the influence of central nervous system inflammation.	22975392
Inflammation, Calcinosis, Hyperplasia, Uterine Fibroids	Altered Intercellular Communication	Histological study showed elongation of the leaflets by myofibrotic and fibrotic hyperplasia without calcification and inflammation in the aortic valve.	22975545
Adrenal Gland Neoplasms, epinephrine, Neoplasms	Altered Intercellular Communication	Adrenal GN is a rare benign tumor, and its hormonal activity and imaging characteristics are occasionally very similar to those of other adrenal tumors.	22975550
Inflammation, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Traumatic injury	Altered Intercellular Communication	Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis.	22975753
Inflammation, AAVS1 gene, Vasculitis, CTCAE	Altered Intercellular Communication	To identify circulating proteins that distinguish between active anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and remission in a manner complementary to markers of systemic inflammation.	22975753
Inflammation, Microbleeds	Altered Intercellular Communication	When patients display asymmetrical subcortical white matter lesions with microbleeds on T(2)* weighted imaging, amyloid angiopathy-related inflammation should be considered.	22975859
Inflammation	Altered Intercellular Communication	As inflammation has been associated with other brain MRI findings, we investigated whether interleukin-6 and C-reactive protein were associated with the severity of dVRS in the eldery.	22976070
Inflammation	Altered Intercellular Communication	We found that elevated interleukin-6 levels were associated with higher severity of dVRS in basal ganglia, suggesting that inflammation might be associated with the burden of dVRS in the elderly.	22976070
Multiple polyps, Disorder of small intestine, Peutz-Jeghers Syndrome, Communicable Diseases, Diverticular Diseases, Celiac Disease, Systemic Scleroderma, Vasculitis, CTCAE, Malignant Neoplasms, Congenital duplication of intestine	Altered Intercellular Communication	In addition, MR enterography has an evolving though less well documented role to play in the evaluation of other small-bowel diseases, including various benign and malignant neoplasms arising in isolation or in polyposis syndromes such as Peutz-Jeghers, inflammatory conditions such as vasculitis and treatment-induced enteritis, infectious processes, celiac disease, diverticular disease, systemic sclerosis, and bowel duplication.	22977028
Thrombosis, Primary malignant neoplasm, Thrombophilia, Unknown (origin) (qualifier value), MVT Regimen, Hypertension, CTCAE, Myeloproliferative disease	Altered Intercellular Communication	Primary MVT is idiopathic, whereas secondary MVT can result from a variety of underlying diseases and risk factors, including primary hypercoagulable states or prothrombotic disorders, myeloproliferative neoplasms, cancer (most frequently of the pancreas or liver), diverse inflammatory conditions, recent surgery, portal hypertension, and miscellaneous causes such as oral contraceptives or pregnancy.	22977032
Inflammation, Primary malignant neoplasm, Telangiectasis	Altered Intercellular Communication	An unusual form of cutaneous infiltration involving a mammary region bearing a post-mastectomy surgical skin scar is herein described: interestingly, such a cutaneous cancer involvement could not be included in the above classification, because it merely consisted of red-purple areas dealing with small telangiectasias, without any sign of inflammation.	22978058
Mycobacterium Infections, Inflammatory abnormality of the eye	Altered Intercellular Communication	Two mechanisms can be proposed at the origin of ocular inflammation: a local immune response or a direct choroidal mycobacterial infection as demonstrated by vitreous cultures.	22978181
Inflammation, Endothelial dysfunction, ETV3 wt Allele	Altered Intercellular Communication	The current study found that individuals with MetS have a higher degree of endothelial dysfunction and inflammation compared with individuals with multiple CV risk factors and may therefore have an increased CV risk beyond the contributions of multiple traditional risk factors.	22980166
Inflammation, Primary malignant neoplasm, Infection	Altered Intercellular Communication	Immunosenescence, the progressive decline of adaptive immunity and chronic inflammation with ageing has been demonstrated to be the main factor responsible for infections, cancer and autoimmune conditions in the elderly.	22980794
Inflammation, Dislocations	Altered Intercellular Communication	Clinical parameters (age, total number of dislocations, and period since initial dislocation) were statistically independent from histopathologic parameters (inflammation, lipomatous changes, vascular proliferation, tissue fragmentation, and cellularity).	22981356
Communicable Diseases, Inflammation	Altered Intercellular Communication	In particular, aging of the immune system is characterized by progressive dysregulation of immune responses, resulting in increased susceptibility to infectious diseases, impaired vaccination efficacy and systemic low-grade chronic inflammation.	22981370
Inflammation, Deficient Food Intake	Altered Intercellular Communication	We hypothesize that epigenetic alterations and nutritional deficits associated with aging may lead to zinc transporter dysregulation, resulting in decreases in cellular zinc levels and enhanced inflammation with age.	22981370
Inflammation	Altered Intercellular Communication	Our data suggested that age-related epigenetic dysregulation in zinc transporter expression may influence cellular zinc levels and contribute to increased susceptibility to inflammation with age.	22981370
Arterial Stiffness, Inflammation, Vascular calcification	Altered Intercellular Communication	Pulse wave velocity (PWV) constitutes a valid index of arterial stiffness osteoprotegerin (OPG) and osteopontin (OPN) which are well-established vascular calcification inhibitors, highly correlated with inflammation, and cardiovascular events incidence.	22982141
Inflammation, Non-Small Cell Lung Carcinoma, Loss, Malignant Neoplasms	Altered Intercellular Communication	The tissue inhibitor of metalloproteinase 3 (TIMP-3) is essential for limiting inflammation; therefore, we expected that TIMP-3 loss might induce chronic inflammation, thereby promoting tumor malignancy as well as poor survival and relapse in patients with HPV-infected non-small cell lung cancer.	22982189
Inflammation, Anxiety, CTCAE 3.0, Depression, CTCAE, Coronary heart disease	Altered Intercellular Communication	Inflammation and symptoms of depression and anxiety in patients with acute coronary heart disease.	22982340
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	ACS was associated with very high levels of inflammation, averaging 13.23x10(9)/l and 17.06 mg/l for white cell count and C-reactive protein respectively.	22982340
Inflammation, Depression, CTCAE, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	The study provides some support for the hypothesis that the marked inflammation during ACS contributes to later depression in a subset of patients, but the evidence is not conclusive.	22982340
Inflammation, Transcription Initiation	Altered Intercellular Communication	The gene variants of the chemokine and chemokine receptor genes associated with inflammation may be involved in cancer initiation and progression.	22982413
Schizophrenia, Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The metabolic syndrome is highly prevalent in patients with schizophrenia, and is associated with a state of chronic, low-grade inflammation.	22982547
Schizophrenia, Inflammation	Altered Intercellular Communication	Schizophrenia is also associated with increased inflammation, including aberrant blood levels of pro-inflammatory cytokines and high-sensitivity C-reactive protein (hsCRP).	22982547
Schizophrenia, Inflammation, metabolic disturbance	Altered Intercellular Communication	Our findings suggest that measurement of total and differential WBC counts and hsCRP blood levels may be germane to the clinical care of patients with schizophrenia and related disorders, and support an association between inflammation and metabolic disturbance in these patients.	22982547
Presenile dementia, Inflammation	Altered Intercellular Communication	Studies that have investigated the association between markers of inflammation and risk of dementia are conflicting.	22982688
methyldopa, Inflammation	Altered Intercellular Communication	The impact of inflammation to the antioxidant defense parameters in AMD patients.	22982945
methyldopa, Inflammation	Altered Intercellular Communication	Oxidative stress and inflammation are postulated to be involved in the pathogenesis of the age-related macular degeneration (AMD) although the mechanism linking the oxidation and inflammation is still unknown.	22982945
Inflammation, Traumatic, Internal anal sphincter, Ischemia	Altered Intercellular Communication	Idiopathic chronic anal fissure is believed to be a consequence of a traumatic acute anodermal tear followed by recurrent inflammation and poor healing due to relative tissue ischaemia secondary to internal sphincter spasm.	22983551
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Patients with chronic obstructive pulmonary disease (COPD) have evidence of systemic inflammation that may be implicated in the development of comorbidities.	22983959
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Although dopamine deregulation has been observed in Alzheimer's disease (AD) patients, the dysfunction of this neurotransmitter has not been investigated in animal models of AD.	22984283
Inflammation, Obesity	Altered Intercellular Communication	To investigate whether the association of tCys with body fat extends to children at particular risk of obesity, and whether tCys is associated with insulin resistance and obesity-associated inflammation.	22984471
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	The questionnaire items 'Red joints', 'Swollen joints', 'Warm joints' suggest differences in the level of inflammation between the groups although c-reactive protein (CRP) and rheumatoid factor (RHF) levels were equal.	22984493
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Previous studies implicated that IL23R and IL17 genes play an important role in autoimmune inflammation.	22984500
ARCN1 gene, Inflammation, Bronchitis	Altered Intercellular Communication	Long-term administration of low-dose inhaled corticosteroids decelerates the annual BMD loss in bronchitic patients, possibly by reducing both pulmonary and systemic chronic inflammation caused by COPD.	22985270
Sjogrens Syndrome", Inflammation, Autoimmune Disorder, CTCAE	Altered Intercellular Communication	The Sjogren's syndrome is a systemic autoimmune disorder characterized by chronic inflammation of the exocrine glands with extraglandular manifestations in up to 25% patients.	22985924
Benign Prostatic Hyperplasia, Inflammation	Altered Intercellular Communication	Pathogenic role of HIF-1a in prostate hyperplasia in the presence of chronic inflammation.	22986049
Inflammation, Large prostate	Altered Intercellular Communication	Although BPH is frequently accompanied by inflammation, it is unclear whether inflammation underlies prostate enlargement.	22986049
Large prostate	Altered Intercellular Communication	Therefore, we hypothesized that cytokines secreted from infiltrated macrophages under inflammatory conditions stimulate prostate enlargement by up-regulating HIF-1a.	22986049
Large prostate, prostatitis	Altered Intercellular Communication	Based on these results, we propose that HIF-1a mediates prostate enlargement under inflammatory conditions, and we suggest that HIF-1a be viewed as a promising target for blocking the transition from prostatitis to BPH.	22986049
Psoriatic Juvenile Idiopathic Arthritis, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	We hypothesize that chronic inflammation is the driving force that enhances the risk of malignancy in psoriatic patients and suspect that psoriatic patients have higher risks for developing cancers that are most prevalent in the studied population.	22986081
Inflammation	Altered Intercellular Communication	During disease progression, inflammation and oxidative stress may well invoke humoral immunity against pathological aggregates of PD-associated a-synuclein.	22986484
Inflammation, Endothelial dysfunction, Complications of Diabetes Mellitus	Altered Intercellular Communication	YKL-40 is a marker of inflammation and endothelial dysfunction, both of which play important roles in the progression of diabetic complications.	22986489
Inflammation, Primary malignant neoplasm, Tumor Cell Invasion, Neoplasms	Altered Intercellular Communication	The pathways of neoplasia, invasion and inflammation are inextricably linked in cancer and aberrations in several regulatory pathways for these processes have been identified.	22986533
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation is a critical participant in mediating all stages of cardiovascular disease.	22986554
Tracheitis	Altered Intercellular Communication	Short-term intubation in healthy patients resulted in significant tracheal inflammation.	22986720
Hyperglycemia	Altered Intercellular Communication	This association is absent in obese patients, who may be primed by obesity-induced inflammation to develop severe hyperglycemia even without experiencing the cytokine storm that is essential to GVHD pathogenesis.	22987342
Inflammation, Necrosis	Altered Intercellular Communication	Fibrinoid necrosis and intramural inflammation were observed in 8 cases.	22987379
Inflammation	Altered Intercellular Communication	Associations between arterial elasticity and markers of inflammation in healthy older women.	22987795
Inflammation, Optic Chiasms, Hypertrophy	Altered Intercellular Communication	MRI: diffuse enlargement of Optic Chiasm with inflammation of distal optic nerves bilateral.	22989339
Inflammation, Asthma	Altered Intercellular Communication	Airway responses and inflammation in subjects with asthma after four days of repeated high-single-dose allergen challenge.	22989372
Airway structure	Altered Intercellular Communication	Therefore, we designed a protocol for repetitive high-dose bronchial allergen challenges to generate clinical symptoms and airway inflammation.	22989372
Symptoms	Altered Intercellular Communication	Repeated high-dose bronchial allergen challenges resulted in severe asthma symptoms and marked Th-2-mediated allergic airway inflammation.	22989372
Fibrosis, Liver, Hepatitis, End Stage Liver Disease	Altered Intercellular Communication	Serum FSAP concentrations declined in patients with end-stage liver disease, and hepatic FSAP expression was decreased in patients with advanced liver fibrosis and liver inflammation.	22989567
Inflammation, Fibrosis Assessment, Injury of liver, Liver diseases	Altered Intercellular Communication	Lower FSAP expression is associated with enhanced liver fibrosis and inflammation in patients with chronic hepatic disorders and murine experimental liver injury.	22989567
Inflammation, Liver Cirrhosis, FAM126A gene	Altered Intercellular Communication	Severe inflammation in the background liver cirrhosis correlates with the development of poorly differentiated HCC in HCV-associated liver cirrhosis.	22989817
Inflammation, Liver carcinoma, Liver Cirrhosis, FAM126A gene	Altered Intercellular Communication	Whether severe inflammation in the background liver cirrhosis might correlate with the development of poorly differentiated human hepatocellular carcinoma (HCC) was studied in hepatitis C virus (HCV)-associated liver cirrhosis.	22989817
Inflammation	Altered Intercellular Communication	Inflammation in the background LC was evaluated by modified histology activity index (HAI).	22989817
Inflammation, Necrosis	Altered Intercellular Communication	To evaluate the inflammation, piece meal necrosis, intra lobular cellular degeneration and focal necrosis, portal cellular inflammation (each 0-4) were estimated.	22989817
Inflammation, Liver Cirrhosis, FAM126A gene	Altered Intercellular Communication	It is suggested that severe inflammation in the background cirrhosis accelerates the promotion in the HCC development from HCV-associated LC.	22989817
Airway structure, Wheezing	Altered Intercellular Communication	The role of bacteria, regulatory T (T(reg)) cells and their association with airway inflammation in preschool wheeze is largely unknown.	22990010
Airway structure, Wheezing	Altered Intercellular Communication	The analysis of EBC might serve as a helpful non-invasive tool to early assess airway inflammation in wheezing children.	22990010
Airway structure, Wheezing	Altered Intercellular Communication	The various elevated exhaled inflammatory markers indicate increased airway inflammation in wheezing preschool children.	22990010
Airway structure, Wheezing	Altered Intercellular Communication	In the presence of wheeze, we found no evidence for bacterial induced airway inflammation.	22990010
Inflammation, Swelling	Altered Intercellular Communication	It is characterized by inflammation of the "bronchial tree" that results in tissue swelling and excessive secretions of mucus into the bronchi, with progressive airflow limitation.	22990540
Inflammation	Altered Intercellular Communication	At points of contact with this material, destruction and severe polymorphic inflammation of the pulmonary parenchyma were noted.	22990635
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver biopsy showed lower inflammation [histological activity index (HAI) = 4] and fibrosis (F) (= 0) scores in genotype D than in genotypes A (HAI = 5, p < 0.001; F = 2, p = 0.008) or F (HAI = 5, p = 0.009; F = 2, p = 0.01).	22990965
Hyperglycemia, Inflammation	Altered Intercellular Communication	The main determinants of hyperglycaemia were an abnormal pre-pneumonia glucose metabolism and the intensity of the pneumonic inflammation.	22991982
Inflammation, Stomach Carcinoma, Neoplasms	Altered Intercellular Communication	PAR-1 has been involved in inflammation of the gastrointestinal tract, tumour cell growth and invasion of gastric carcinoma cells.	22993310
Inflammation, Tuberculosis, Unknown (origin) (qualifier value), Sarcoidosis, Orbital Myositis, Hyperthyroidism	Altered Intercellular Communication	Orbital myositis is inflammation of the extraocular muscles and can be either idiopathic, without a known etiology, or secondary to conditions such as tuberculosis, sarcoidosis, or hyperthyroidism.	22993891
Inflammation	Altered Intercellular Communication	Positive correlations were found between the markers of vascular endothelial activation and those of inflammation.	22994085
Sepsis, Inflammation, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is considered as a moderate systemic inflammation and we hypothesise that this chronic condition could have an impact on the outcome in sepsis.	22994591
Inflammation, physiopathological	Altered Intercellular Communication	We present a case of temporary cochlear nerve dysfunction due to endocochlear inflammation with subsequent recovery.	22995199
Inflammation	Altered Intercellular Communication	Continuous cochlear nerve stimulation at various levels may aid in function recovery after endocochlear inflammation.	22995199
Airway structure, Cystic Fibrosis	Altered Intercellular Communication	Although the increase in systemic inflammatory markers requires further evaluation, CXCR2 antagonism may be a useful approach for modulating airway inflammation in patients with cystic fibrosis.	22995323
Inflammation, Fibrosis Assessment, Edema, Lymphangiectasis	Altered Intercellular Communication	Microscopically, all cases exhibited stromal fibrosis and edema, multinucleated stromal cells, perivascular chronic inflammation, and lymphangiectasia.	22995331
Virus Diseases, Hepatitis, Chronic, FAM126A gene	Altered Intercellular Communication	The pathogenesis of HCC is closely associated with chronic liver inflammation fired by a variety of stimulates such as virus infection and metabolic stress.	22996042
Inflammation, Organ Dysfunction Scores, Bacterial Infections	Altered Intercellular Communication	During bacterial infection, activated polymorphonuclear leukocytes (PMNs) often cause inflammation and organ dysfunction in severely ill patients.	22996209
Inflammation	Altered Intercellular Communication	Inflammation is assumed to act in the pathogenesis of both diseases.	22996633
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Growth differentiation factor 15 (GDF15), a stress-responsive cytokine produced in cardiovascular cells under conditions of inflammation and oxidative stress, is emerging as an important prognostic marker in individuals with and without existing cardiovascular disease (CVD).	22997280
Leprosy	Altered Intercellular Communication	Leprosy is characterised by a chronic granulomatous inflammation of the skin and peripheral nerves.	22997696
Lung Diseases, Obstructive	Altered Intercellular Communication	[Comparative characteristic of the hormonal profile in men with stable obstructive pulmonary disease and smokers].	22997716
ARCN1 gene, Signs and Symptoms, Respiratory, Abnormal breathing, Chronic Obstructive Airway Disease, Bronchitis, Chronic	Altered Intercellular Communication	Comparative analysis of the hormonal profile was performed in 12 and 16 patients with mild and moderately severe chronic obstructive pulmonary disease (COPD) respectively, in 25 patients with chronic bronchitis, 13 smokers without respiratory symptoms and dysfunction of external respiration, and in healthy non-smokers.	22997716
Inflammation, antimony, Attack behavior, Arthritis, Calcium pyrophosphate deposition disease, Hypomagnesemia	Altered Intercellular Communication	Despite the rarity of this condition, it is important to know that hypomagnesaemia may be associated with calcium pyrophosphate crystal inflammatory arthritis (chondrocalcinosis) and that SBS patients may be prone to develop extreme hypomagnesaemia causing recurrent joint attacks without systemic inflammation.	22998213
Hashimoto Disease, Inflammation	Altered Intercellular Communication	Inflammation and increased myxovirus resistance protein A expression in thyroid tissue in the early stages of Hashimoto's thyroiditis.	22998463
Inflammation	Altered Intercellular Communication	Inflammation, expression of MxA, and the presence of the enteroviralcapsid protein (VP1) were characterized by immunohistochemistry.	22998463
Inflammation, Inflammatory disease of mucous membrane	Altered Intercellular Communication	In H. pylori-infected subjects, antral mucosal inflammation and activity improved significantly (P < 0.001) and stabilised after 3 years on esomeprazole while no change in inflammation was observed after LARS.	22998687
Inflammation, Peripheral visual field loss	Altered Intercellular Communication	Thus, the gradual relative loss of peripheral fat in aging humans may in part result from a defect in adipogenesis, which may be linked to inflammation and increased release of proinflammatory cytokines from fat tissue.	22999012
Inflammation	Altered Intercellular Communication	Unlike in many other inflammatory conditions, plasma suPAR levels do not reflect inflammation in AS.	22999906
Inflammation	Altered Intercellular Communication	Unlike in many other inflammatory conditions, plasma suPAR levels do not reflect inflammation in AS.	22999906
Osteoporosis	Altered Intercellular Communication	Interleukin-6 (IL-6) is produced by osteoblasts, and potently stimulates osteoclast activation playing a key role in normal bone resorption as well as in post-menopausal and inflammation-driven osteoporosis.	22999910
Osteoporosis	Altered Intercellular Communication	These data may provide further rationale for employing rosuvastatin to beneficially affect bone metabolism in post-menopausal women and possibly in inflammation-driven osteoporosis.	22999910
Inflammation, Venous Thromboembolism, vinyltriethoxysilane	Altered Intercellular Communication	Since venous thromboembolism (VTE) is associated with systemic inflammation and mortality as well, we have hypothesized that it is also associated with elevated vitamin B12 serum levels in elderly patients following major orthopedic surgery of the lower limb.	23000313
Inflammation, Fibrosis Assessment, Capsulitis, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Evidence suggests ACH may present in a similar progression through four stages as adhesive capsulitis of the shoulder (ACS) (from synovial inflammation to capsular fibrosis).	23000348
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, lung growth, Asthma	Altered Intercellular Communication	Persistent chronic inflammation and impaired lung growth due to asthma in childhood may have long-term impact on pulmonary function and increase susceptibility to chronic obstructive pulmonary disease (COPD) in later life.	23000796
Nonspecific interstitial pneumonia, Pneumonia, Interstitial, HIV, Interstitial inflammation	Altered Intercellular Communication	The term nonspecific interstitial pneumonia (NSIP) was first used in relation to a pattern of lung interstitial inflammation seen in association with human immunodeficiency virus (HIV) infection.	23001799
Interstitial inflammation, Pneumonia, Fibrosis Assessment, Bronchiolitis Obliterans, Pneumonia, Interstitial	Altered Intercellular Communication	In 1994 NSIP was used to indicate a group of subacute or chronic interstitial pneumonias characterized morphologically by interstitial inflammation or fibrosis or both, with preservation of the lung architecture and the absence of typical findings for any of the other main categories of IIP (mainly usual interstitial pneumonia, desquamative interstitial pneumonia, and bronchiolitis obliterans organizing pneumonia).	23001799
Malignant mesothelioma, Inflammation, effusion	Altered Intercellular Communication	Forty three effusion cytology CBs of 25 confirmed malignant mesotheliomas were compared to CBs of 23 benign mesothelial effusions without inflammation and 13 reactive mesothelial proliferations associated with inflammation.	23002041
Inflammation, Peyronie Disease	Altered Intercellular Communication	Peironimev-Plus(r) in the treatment of chronic inflammation of tunica albuginea (Peyronie's disease).	23004005
vascular inflammations, Cardiac fibrosis, Cardiovascular Diseases	Altered Intercellular Communication	Mineralocorticoid Receptor (MR) activation is involved in blood pressure regulation and the pathogenesis of cardiovascular diseases, such as cardiac fibrosis, vascular inflammation and arterial aging.	23006216
Inflammation, Asthma	Altered Intercellular Communication	Exogenous PD1 conferred protection against eosinophilic inflammation in animals with experimental asthma, although its endogenous cellular source and functions in human airways are of interest.	23006546
Inflammation, Asthma	Altered Intercellular Communication	These observations are a first indication that activated human eosinophils represent a major source of PD1, which can act as a self-resolving machinery in eosinophilic inflammation, whereas the production of PD1 is impaired in patients with severe asthma.	23006546
Seizures, Inflammatory disease of mucous membrane	Altered Intercellular Communication	In addition, a positive FIT (>=100 ng/ml) predicted mucosal inflammation (Mayo 2 or 3) with sensitivity 0.87 and specificity 0.60, respectively.	23007005
Inflammation, Myocardial Infarction, Myocardial dysfunction	Altered Intercellular Communication	Compared with MICE, HIIE demonstrated a higher exercise adherence and was well tolerated in patients with HFREF, while still providing a high-level physiological stimulus and leaving indices of inflammation (CRP), myocardial dysfunction (BNP), and myocardial necrosis (cTnT) unaffected.	23007142
Stomach Carcinoma	Altered Intercellular Communication	Significance of the inflammation-based Glasgow prognostic score for short- and long-term outcomes after curative resection of gastric cancer.	23007284
Inflammation, Data types - Address	Altered Intercellular Communication	AR-GG27(r) showed a beneficial action associated with high compliance and tolerability in dermatological skin conditions characterized by inflammation and tissue oxidative stress in children, as PA with mild and moderate AD.	23007324
Airway structure, Asthma	Altered Intercellular Communication	Patients and their parents were educated about this disease (mechanism of asthma, airway inflammation, and necessity of asthma medication) and instructed to visit clinics regularly every 30 days.	23007333
Colitis	Altered Intercellular Communication	The expression levels of CCL20 mRNA and protein were significantly increased in the model group compared with those in the control group (P<0.01) and positively correlated with the severity of colonic inflammation.	23008075
Inflammation, Rosacea	Altered Intercellular Communication	Although inflammation appears to play a pathogenic role in rosacea, initiating factors are largely unknown.	23009116
Acute inflammation, Edema	Altered Intercellular Communication	Seven immunocompetent patients experienced acute anterior inflammation with graft oedema and pigmented keratic precipitates after penetrating keratoplasty.	23009154
Communicable Diseases, Inflammation, Amyloidosis	Altered Intercellular Communication	Infection (n = 10; 58.8%) was the most common cause of secondary amyloidosis during the 1990s, whereas chronic inflammation (n = 14; 48.2%) was the most common cause in 2000s.	23009273
Inappropriate ADH Syndrome	Altered Intercellular Communication	[Gait instability revealing a syndrome of inappropriate antidiuretic hormone secretion associated to pregabalin].	23010093
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	As the lesion matures, inflammation becomes less intense and the fibrosis progresses with an onion-skin type perivascular fibrosis.	23010402
Infarction, Inflammation, Contusions	Altered Intercellular Communication	Compared with controls, patients who were monitored had more pathologic changes related to invasive EEG monitoring (n = 171 [75.7%] vs n = 12 [21.8%]; P < .0001) including meningeal or parenchymal chronic inflammation (n = 128 [56.4%] vs n = 11 [20.4%]; P < .0001) and acute contusion and/or acute/subacute infarct (n = 110 [48.5%] vs n = 0; P < .0001).	23010704
Inflammation	Altered Intercellular Communication	The most common pathologic changes related to invasive monitoring were chronic inflammation and contusion/infarct.	23010704
palladium, Inflammation	Altered Intercellular Communication	It is important to establish the definition of persistent inflammation in the peritoneal cavity at the cessation of peritoneal dialysis (PD).	23010754
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	It appears that PTX3 may be a new biomarker of peritoneal inflammation and progressive fibrosis.	23010754
Inflammation, Calcinosis	Altered Intercellular Communication	The process of calcification may be mediated by inflammation, which also may be related to multiple injections of air into the anterior chamber.	23010776
Inflammation, Arthritis, Hypersensitivity	Altered Intercellular Communication	Methylsulfonylmethane (MSM), which is one of the popular ingredients of so-called health foods in Japan, is expected to relieve inflammation in arthritis and allergies.	23011466
Primary immune deficiency disorder, Inflammation, Chronic granulomatous disease, Infection	Altered Intercellular Communication	Chronic Granulomatous Disease (CGD) is a rare primary immunodeficiency that predisposes to life-threatening infections and inflammation.	23011479
Inflammation, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	Untreated obstructive sleep apnoea (OSA) is characterised by elevated systemic and local oxidative stress and inflammation.	23011770
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Non-invasive measurement of metabolites and markers of inflammation in exhaled breath condensate (EBC) is of interest in the interpretation of systemic effects of severe obstructive sleep apnoea.	23011770
Inflammation, Osage language	Altered Intercellular Communication	This primarily represents a reduction of local inflammation and oxidative stress in the airways, but also indicates a positive effect on elevated oxidative stress in OSA.	23011770
Dystrophy, Inflammation	Altered Intercellular Communication	There were statistical significant differences between the types of dystrophy and inflammation (0.021), creatine kinase levels (p= 0.001), age (p=0.001), and gender (p < 0.001) of the patients.	23011829
Inflammation, Atherosclerosis	Altered Intercellular Communication	A-FABP (adipocyte fatty acid-binding protein), one of the most abundant proteins in adipocytes, plays a key role in obesity-related insulin resistance, inflammation and atherosclerosis in animals.	23013043
Granulomatous inflammation, Vegetation	Altered Intercellular Communication	The vegetations showed granulomatous inflammation but blood cultures and other biological specimen cultures were negative for any organisms.	23013220
Inflammation, Joint Tuberculosis, Degenerative polyarthritis, Rheumatoid Arthritis, Arthritis, Juvenile rheumatoid arthritis	Altered Intercellular Communication	Rice body formation is a nonspecific response to chronic synovial inflammation associated with tuberculous arthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, seronegative inflammatory arthritis, and even osteoarthritis.	23013846
Inflammation, Diabetic Angiopathies	Altered Intercellular Communication	Inflammation is postulated to play a role in diabetogenesis and its further vascular complications.	23014248
Inflammation, Dyslipidemias	Altered Intercellular Communication	Low grade systemic inflammation, in association with dyslipidemia, plays a role in diabetogenesis and its complications.	23014248
Inflammation, Atherosclerosis	Altered Intercellular Communication	Both neoangiogenesis and inflammation contribute in atherosclerosis progression.	23014482
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Histological assessment found CD68 positive multinucleated giant cells in a highly cellular fibroblastic matrix surrounding bony lamellar structures, without signs of inflammation or malignancy.	23015296
Inflammation, Primary malignant neoplasm, Neoplasm Metastasis	Altered Intercellular Communication	E-selectin plays an important role in the process of inflammation and is also involved in the mechanism of cancer metastasis regulating the adhesion of circulating cancer cells to the blood vessels.	23015400
Inflammation, Albuminuria	Altered Intercellular Communication	Inflammation, oxidative stress, glomerular filtration rate, and albuminuria in elderly men: a cross-sectional study.	23016573
Renal Insufficiency, Inflammation	Altered Intercellular Communication	The role of inflammation and oxidative stress in mild renal impairment in the elderly is not well studied.	23016573
Inflammation, Renal function	Altered Intercellular Communication	Our data indicate that cytokine-mediated inflammation is involved in the early stages of impaired kidney function in the elderly, but that cyclooxygenase-mediated inflammation does not play a role at this stage.	23016573
Parkinson Disease, Lewy Bodies, palladium, Inflammation	Altered Intercellular Communication	Lewy pathology affects the gastrointestinal tract in Parkinson's disease (PD) and data from recent genetic studies suggest a link between PD and gut inflammation.	23017648
palladium, Gastrointestinal inflammation	Altered Intercellular Communication	We therefore undertook the present survey to investigate whether gastrointestinal inflammation occurs in PD patients.	23017648
palladium, Inflammation	Altered Intercellular Communication	Our findings provide evidence that enteric inflammation occurs in PD and further reinforce the role of peripheral inflammation in the initiation and/or the progression of the disease.	23017648
Celiac Disease, Inflammation, Intestinal Diseases	Altered Intercellular Communication	Celiac disease is a permanent enteropathy caused by the ingestion of gluten, which leads to an immunemediated inflammation of the small intestine mucosa.	23018296
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Inflammation and circulating endothelial progenitor cells in patients with coronary artery disease and residual platelet reactivity.	23018312
Inflammation	Altered Intercellular Communication	Low-level HIV viremia is associated with microbial translocation and inflammation.	23018379
Inflammation, Heart Failure, Systolic	Altered Intercellular Communication	Increased low-grade inflammation is associated with lack of functional response to carvedilol in patients with systolic heart failure.	23018486
Inflammation, Heart failure, Ventricular Dysfunction	Altered Intercellular Communication	Increased inflammatory activation observed only in heart failure patients not improving left-ventricular function after carvedilol may indicate that inflammation, either as a direct cause or as a consequence, is associated with progressive ventricular dysfunction.	23018486
Inflammation	Altered Intercellular Communication	This study showed decreased proportions of T(reg) in SIgAD patients, particularly in those with signs of chronic inflammation.	23018812
Hyperprolactinemia, Hypopituitarism	Altered Intercellular Communication	On hormonal examination, hypopituitarism with mild hyperprolactinemia was noted.	23019401
Inflammation, Uveitis	Altered Intercellular Communication	Typically, uveitis was bilateral (89%), chronic (89%), intermediate (89%), and associated with previous inflammation (29%), with synechiae (65%), and granulomatous (44%).	23021230
Inflammation, Myocardial	Altered Intercellular Communication	Biomarkers of myocardial damage and inflammation (ie, troponin I, creatine kinase-MB, myoglobin, C-reactive protein) rose in serum 2- to 812-fold after ASA (P < .01).	23021916
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Experimental and epidemiological studies have revealed that chronic inflammation contributes to cancer progression and even predisposes to cellular transformation.	23023232
Inflammation	Altered Intercellular Communication	The activation of the above receptors results in the secretion of growth, chemotactic and angiogenic factors that contribute to chronic inflammation.	23023232
Inflammatory abnormality of the eye, Necrosis, Scleritis	Altered Intercellular Communication	After that, the introduction of an anti-tumor necrosis factor a drug (infliximab) completely resolved the severe scleritis and there was no recurrence of ocular inflammation.	23023405
Inflammation, Hemorrhage	Altered Intercellular Communication	anaesthetics, chemotherapy) or contrast media, bleeding, and inflammation.	23023442
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Consumption of omega-3 fatty acid supplements is highly recommended to alleviate inflammation caused by type 2 diabetes mellitus.	23023905
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Increased risk of mortality in patients with CKD has been attributed to inflammation.	23024164
Inflammation, Albuminuria, Chronic Kidney Diseases	Altered Intercellular Communication	However, the association between kidney function, albuminuria, and biomarkers of inflammation has not been examined in a large cohort of CKD patients.	23024164
TNF protein, human, Inflammation	Altered Intercellular Communication	An inflammation score was established based on plasma levels of IL-1b, IL-6, TNF-a, hs-CRP, and fibrinogen.	23024164
Inflammation, Albuminuria	Altered Intercellular Communication	Biomarkers of inflammation were inversely associated with measures of kidney function and positively with albuminuria.	23024164
Communicable Diseases, Inflammation	Altered Intercellular Communication	Fluorodeoxyglucose positron emission tomography-computed tomography (18FDG PET-CT) has recently gained enthusiasm for its ability to detect infection and inflammation.	23025952
Cholecystitis	Altered Intercellular Communication	18FDG PET-CT detected gallbladder inflammation in all but one patient with pathology-proven cholecystitis with a sensitivity and specificity of 0.90 and 1.00, respectively.	23025952
Hepatitis, Chronic, Disease	Altered Intercellular Communication	PMCs in both diseases had significantly increased TLR 9 expression perhaps implicating TLR9 expression in chronic liver inflammation.	23026026
Inflammation	Altered Intercellular Communication	Multilocular cystic structures accompanied by acute and chronic inflammation were observed in the remnant thymic tissues.	23026930
Multilocular Thymic Cyst, Malignant Neoplasms	Altered Intercellular Communication	Multilocular thymic cysts (MTCs) are considered to be acquired lesions associated with various inflammatory conditions and/or malignant tumors.	23026930
Inflammation, Neoplasms	Altered Intercellular Communication	(89)Sr accumulation seemed to be associated with bone turnover, in particular bone resorption, and vascularization due to inflammation or tumor growth.	23027203
Inflammation, Typhlitis, Epithelial, Edema, Hyperplasia	Altered Intercellular Communication	At 16 wpi, the ceca of H. bilis-infected Rag2(-/-) mice treated with control liposomes had significantly higher histopathological lesional scores (for cumulative typhlitis index, inflammation, edema, epithelial defects, and hyperplasia) and higher counts of F4/80(+) macrophages and MPO(+) neutrophils compared to H. bilis-infected Rag2(-/-) mice treated with clodronate liposomes.	23027534
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	These findings provide novel pathological evidence for inflammation and DDR in influencing non-metastatic progression of cancer in its microenvironment.	23027622
Inflammation	Altered Intercellular Communication	Associations may be modified by lifestyle factors that influence inflammation and oxidative stress.	23027623
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Only the rate of alveolar exudate/oedema in exudative phase cases (P = 0.003); those of alveolar histiocytic desquamation (P = 0.037), alveolar fibrosis (P = 0.017), chronic inflammation (P = 0.02), and alveolar fibrin (P = 0.001) in proliferative cases were significantly higher.	23028252
vascular inflammations, Rickettsia Infections	Altered Intercellular Communication	The pathophysiological hallmark of spotted fever group rickettsioses comprises vascular inflammation.	23028464
Inflammation, Rickettsia Infections	Altered Intercellular Communication	Based on the emerging importance of the wingless (Wnt) pathways in inflammation and vascular biology, we hypothesized that Dickkopf-1 (DKK-1), as a major modulator of Wnt signaling, could be involved in the pathogenesis in rickettsial infections.	23028464
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	Heparanase is an endo-b-glucuronidase that cleaves heparan sulfate side chains, leading to structural modifications that loosen the extracellular matrix barrier and associated with tumor metastasis, inflammation and angiogenesis.	23028487
Stomach Carcinoma	Altered Intercellular Communication	Our findings suggest that certain variants in the innate immunity and NHL-related genes affect the gastric cancer risk, perhaps by modulating infection-inflammation-immunity mechanisms that remain to be defined.	23028900
Inflammation, HIV-1 Infection Pathway	Altered Intercellular Communication	In progressive HIV-1 infection in horizontally infected adults, inflammation, T cell activation, and perturbed T cell differentiation lead to an "immune exhaustion", with decline in T cell effector functions.	23029209
Inflammation	Altered Intercellular Communication	A better understanding of the underlying molecular mechanisms causing systemic inflammation after CPB may aid in the development of new therapeutic approaches.	23029213
Inflammation, Atherosclerosis	Altered Intercellular Communication	T-cell phenotypes, apoptosis and inflammation in HIV+ patients on virologically effective cART with early atherosclerosis.	23029393
Inflammation	Altered Intercellular Communication	Chronic inflammation is a major contributing factor in the pathogenesis of many age-associated diseases.	23029496
Granulomatous inflammation, diabetic	Altered Intercellular Communication	We report a case of granulomatous inflammation in the prostate as a result of crypyococcus neoformans infection in a 70 year old immunocompetent patient, a non diabetic, which was diagnosed by transrectal ultrasound guided biopsy.	23029729
Inflammation, Vascular System Injuries	Altered Intercellular Communication	Osteoprotegerin (OPG) is known to regulate processes involved in vascular injury and inflammation.	23030274
Inflammation, Impaired T cell function	Altered Intercellular Communication	It was reported that anti-endothelial cell antibodies (AECAs) are associated with endothelial cell dysfunction and inflammation.	23030505
Salmonella enterica subsp. salamae, Granulomatosis, Cutaneous Small Vessel Vasculitis, Genus staphylococcus, Chronic necrotizing inflammation, Systemic Vasculitis	Altered Intercellular Communication	In granulomatosis with polyangiitis (GPA), a complex autoimmune small-vessel vasculitis frequently associated with chronic necrotizing inflammation of the nasal mucosa, elevated nasal Staphylococcus (S.) aureus carrier rates are a risk factor for relapse.	23031229
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Matrix metalloproteinases (MMPs) are implicated in the destruction of the joint and have been shown to be strongly associated with inflammation in rheumatoid arthritis (RA).	23031278
Inflammation, Leukocytosis, Brain Injuries	Altered Intercellular Communication	Leukocytosis at the time of ND correlates with poor functional outcomes and may represent a marker of greater cerebral damage through increased parenchymal inflammation.	23031742
Necrotizing granulomatous inflammation, Specimen Type - Fistula, Ulcer, Esophageal Stricture, Crohn Disease	Altered Intercellular Communication	The resected specimen and pathological results confirmed a deep linear ulcer, chronic and noncaseating granulomatous inflammation, as well as a circular stricture of the esophagus with fistula into the mediastinum due to isolated esophageal Crohn's disease.	23031794
Autoimmune Diseases	Altered Intercellular Communication	Those vesicles have recently been recognized as mediators of intercellular communication or as adjuvant in the pathogenesis of autoimmune diseases.	23031801
Granulomatous, Melanin pigmentation, Retroperitoneal fibrosis, Neoplasms	Altered Intercellular Communication	Retroperitoneal sclerosing PEComa with melanin pigmentation and granulomatous inflammation-a rare association within an uncommon tumor.	23032844
Granulomatous inflammation, Perivascular Epithelioid Cell Neoplasms, Neoplasms	Altered Intercellular Communication	Presence of melanin pigment and granulomatous inflammation in the present tumor constitute as novel histopathological findings in a sclerosing PEComa.	23032844
Glaucoma, CTCAE, Conjunctivitis	Altered Intercellular Communication	Conjunctival inflammation in patients under topical glaucoma treatment with indication to surgery.	23033136
Inflammation	Altered Intercellular Communication	Use of the retraction system failed in three out of five patients (60%) with intraoperative signs of chronic inflammation and in one out of 13 (7.1%) without such signs (p = 0.0441).	23033957
Extravasation of bile, Inflammation	Altered Intercellular Communication	Internal retraction enables a safe exposure of the Calot triangle avoiding bile spillage in cholecystectomies without intraoperative signs of inflammation.	23033957
Inflammation, Arteriosclerosis	Altered Intercellular Communication	Angiotensin receptor blockers (ARBs) are reported to provide direct protection to many organs by controlling inflammation and decreasing oxidant stress in patients without arteriosclerosis.	23034088
Inflammation, Pain Distress Question	Altered Intercellular Communication	We hypothesize that oxygen-ozone injections in paravertebral regions can induce a direct reduction of root inflammation with a corresponding reduction of pain.	23034266
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Pathology, Obesity	Altered Intercellular Communication	Chronic adipose tissue inflammation is a hallmark of obesity, triggering the development of associated pathologies, particularly type 2 diabetes.	23034965
Myocarditis, Lupus Erythematosus	Altered Intercellular Communication	The diagnostic role of cardiac magnetic resonance imaging in detecting myocardial inflammation in systemic lupus erythematosus.	23035042
Viral myocarditis, Lupus Erythematosus, Myocarditis, Lupus Erythematosus, Systemic	Altered Intercellular Communication	The objective of this paper is to evaluate the diagnostic role of cardiac magnetic resonance imaging (CMR) in detecting myocardial inflammation in systemic lupus erythematosus (SLE) and its differentiation from viral myocarditis.	23035042
Inflammation, Sepsis, Tissue damage, Single organ dysfunction, Intravascular Route of Drug Administration, Cessation of life	Altered Intercellular Communication	Severe sepsis is characterised by intravascular or extravascular infection with microbial agents, systemic inflammation and microcirculatory dysfunction, leading to tissue damage, organ failure and death.	23036162
Sepsis, Inflammation, physiopathological	Altered Intercellular Communication	Administration of MAT.Ang-1 after the onset of sepsis protects the microcirculation from endotoxemia-induced vascular dysfunction through reducing inflammation but without pro-angiogenic actions, thus representing a novel, potential pharmacotherapeutic agent for the treatment of sepsis.	23036162
Inflammation	Altered Intercellular Communication	After first assessment, GCA was considered unlikely, since the sedimentation rate, as a marker for inflammation, was only slightly elevated.	23036565
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Dendritic cells provide a potential link between smoking and inflammation in rheumatoid arthritis.	23036591
Inflammation, Nasal Polyps, Neoplasms	Altered Intercellular Communication	Isolated REAH, which may mimic a neoplasm, appears to be a different clinical entity than the more common form encountered in association with nasal polyps and inflammation.	23038055
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Inflammation was detected in over one-third of the participants, emphasizing the inflammatory component of OA and a possible important role for anti-inflammatory therapies in knee OA.	23039323
Inflammation	Altered Intercellular Communication	Our findings suggest that miR-21 may be a new biomarker of inflammation.	23041385
Intraocular inflammation	Altered Intercellular Communication	To investigate the posterior segment in cases of clinically evident intraocular inflammation for punctate reflections consistent with that expected to arise from inflammatory cells.	23042101
Intraocular inflammation	Altered Intercellular Communication	Eyes with intraocular inflammation had SD-OCT images of the vitreous containing punctate spots of a size consistent with that expected from inflammatory cells.	23042101
Inflammation	Altered Intercellular Communication	These results may imply a role for subclinical systemic inflammation and a beneficial effect of statins in the development of HPR in T2DM.	23042313
Inflammation, AMYOTROPHY, HEREDITARY NEURALGIC	Altered Intercellular Communication	Surgery and childbirth can trigger attacks of hereditary brachial plexus neuropathy (HBPN), and inflammation was suggested as a component of the pathogenesis.	23042485
Airway structure, Asthma	Altered Intercellular Communication	Clinical control of asthma associates with measures of airway inflammation.	23042704
Airway structure, Asthma	Altered Intercellular Communication	The Global Initiative for Asthma defined control by a composite measure of clinical findings and future risk but without using markers of airway inflammation, the hallmark of asthma.	23042704
Inflammation, Asthma	Altered Intercellular Communication	We investigated whether clinical asthma control reflects eosinophilic inflammation in a broad population.	23042704
Inflammation, Dental Plaque	Altered Intercellular Communication	At initial clinical examination, plaque accumulation, gingival inflammation and temporary restorations were noted.	23043885
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Genetic variation in innate immunity and inflammation pathways associated with lung cancer risk.	23044494
Carcinoma of lung, Pneumonitis	Altered Intercellular Communication	Pulmonary inflammation may contribute to lung cancer etiology.	23044494
Inflammation, Carcinoma of lung	Altered Intercellular Communication	The current findings add to evidence implicating inflammation and immunity in lung cancer etiology.	23044494
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Ultrasound joint inflammation in rheumatoid arthritis in clinical remission: how many and which joints should be assessed?	23044729
Refractory anemias, Arthritis, MTTP wt Allele	Altered Intercellular Communication	US assessment of the wrist, MCP, ankle, and MTP joints can be highly sensitive for detecting residual B-mode and Doppler joint inflammation in RA patients.	23044729
Inflammation, Infiltration, Edema	Altered Intercellular Communication	In addition, we used fat saturation to distinguish T2 changes caused by edema and inflammation from fat infiltration in muscles.	23044995
Inflammation	Altered Intercellular Communication	Integrin-linked kinase (ILK) is an intracellular protein implicated in chronic inflammation and neoplastic transformation.	23045294
Inflammation, Virus Diseases, Diffuse Large B-Cell Lymphoma	Altered Intercellular Communication	Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with an association with inflammation and viral infections.	23046110
Paroxysmal nocturnal hemoglobinuria, Pancytopenia, eculizumab	Altered Intercellular Communication	Eculizumab is efficacious in patients with PNH, but responses can vary and may depend on underlying marrow failure, underlying inflammatory conditions and red cell clone size following treatment.	23046169
Inflammation, Periodontitis	Altered Intercellular Communication	Chronic periodontitis (CP) is a chronic inflammation associated with elevations of several inflammatory and cardiac markers.	23046680
Chronic Kidney Diseases	Altered Intercellular Communication	Malnutrition-inflammation score is associated with handgrip strength in nondialysis-dependent chronic kidney disease patients.	23046737
Inflammation	Altered Intercellular Communication	Chronic inflammation may not severely affect the CTN in pediatric patients, resulting in higher incidences of CTN regeneration and gustatory function recovery after severing the nerve, compared with those in adult patients.	23047264
Inflammation	Altered Intercellular Communication	We analyzed the hospital stay, the morbidity, the cost, and the severity of the inflammation and compared the open appendicectomy [OA (78)] with the LA (57) approach.	23047396
Inflammation, Neoplasms	Altered Intercellular Communication	Multivariate analysis including HMGB1, tumor, liver and inflammation markers revealed HMGB1 and CRP as independent prognostic parameters.	23047645
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	A reduction in collagen III content, particularly away from the atherosclerotic lesions, might be explained by the systemic vascular changes in patients with MI, and inflammation and immune responses could be potential causes of these systemic transformations.	23049084
Spermatic Cord Torsion, Pain Distress Question, Inflammation, Erythema, Swelling, Testicular Neoplasms	Altered Intercellular Communication	Even though the common causes of scrotal erythema with local swelling and pain are orchiepididimitis and testicular torsion, a careful examination followed by a precise ultrasound can reveal a developing testicular tumor, which was complicated by inflammation.	23049638
Diabetic Nephropathy, Fibrosis Assessment, Nephritis, diabetic	Altered Intercellular Communication	At the end of 3-month SFN treatment, the diabetic nephropathy, shown by renal inflammation, oxidative damage, fibrosis, and dysfunction, was significantly prevented along with an elevation of renal Nrf2 expression and transcription in diabetes/SFN group compared with diabetic group.	23050040
Inflammation, Atherosclerosis	Altered Intercellular Communication	Consequently, inflammation and atherosclerosis and its complications are in good correlation.	23050404
Communicable Diseases, Inflammation	Altered Intercellular Communication	Tb4 likely acts to repair and regenerate wounds by promoting cell migration and stem cell mobilization and differentiation, and by inhibiting inflammation, apoptosis, and infection.	23050815
Inflammation, Endocardium, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Plasma proteins mediate thrombogenesis, inflammation, endocardial injury and structural remodelling in atrial fibrillation (AF).	23052711
Inflammation, Disorder of the optic nerve	Altered Intercellular Communication	Although two eyes showed LP(-) due to optic neuropathy, those eyes showed a remission in inflammation and an increase in IOP.	23052719
Communicable Diseases, Inflammation	Altered Intercellular Communication	Infection and inflammation were associated with development of hyperTG [C-reactive protein (CRP), r (2) = 0.19, p = 0.004].	23052949
Gastrointestinal Stromal Tumors, Inflammation	Altered Intercellular Communication	Elevated blood NLR appears to represent systemic inflammation in patients with high-risk GIST.	23054118
Inflammation	Altered Intercellular Communication	Hypertrophic scar (HS) is a cutaneous fibrotic disorder characterized by persistent inflammation, excessive proliferation of fibroblasts, and abundant accumulation of extracellular matrix (ECM) proteins.	23054143
palladium, Inflammation	Altered Intercellular Communication	Here we review evidence that a-synuclein activates glia inducing inflammation and that Nrf2-directed phase-II antioxidant enzymes play an important role in PD.	23054368
palladium, Inflammation	Altered Intercellular Communication	This complex a-synuclein-directed glial response highlights the importance of protein misfolding, oxidative stress and inflammation in PD and represents a potential locus for the development of novel therapeutics focused on induction of the Nrf2-directed antioxidant pathway and inhibition of protein misfolding.	23054368
Eosinophilic disorder, Inflammation, Neurologic Deficits	Altered Intercellular Communication	Biological markers of inflammation or eosinophilia were present in 5/8 and a progressive motor deficit (7/8) is suggestive of the diagnosis.	23054406
Inflammation, Dental Plaque	Altered Intercellular Communication	Plaque destabilization results from the synergy between intraplaque angiogenesis and inflammation.	23054554
Inflammation, Traumatic injury	Altered Intercellular Communication	Trauma and severe inflammation may be good indications for en masse lobectomy.	23054617
Tumor necrosis, Inflammation, Psoriasis	Altered Intercellular Communication	The tumor necrosis factor alpha-induced protein 3 (TNFAIP3) gene functions in negative-feedback regulation of inflammation, and its single nucleotide polymorphism is associated with psoriasis.	23054742
Inflammation, Impaired cognition, Data types - Address	Altered Intercellular Communication	Decreased adiponectin may be a surrogate marker of the pathological process in AD, linking clinical comorbidities, inflammation and cognitive dysfunction.	23055000
Inflammation, Primary malignant neoplasm, Pathology	Altered Intercellular Communication	UNC5B is a membrane-bound receptor of the neural guidance factor netrin-1 family, with important roles in angiogenesis, neurogenesis, embryonic development, cancer, inflammation and various pathologies.	23055195
Inflammation	Altered Intercellular Communication	Heme oxygenase-1 (HO-1), a rate-limiting enzyme in heme catabolism, is known to play a role in the protection of cells against oxidative stress, inflammation, anomalous proliferation and apoptosis.	23055342
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The aim of this study is to determine the role of aB-crystallin in chronic obstructive pulmonary disease (COPD) pathogenesis and inflammation.	23055712
Chronic Obstructive Airway Disease, Acute inflammation	Altered Intercellular Communication	The same could be observed comparing the group of patients with acute inflammation and non-COPD healthy smokers (P = 0.007).	23055712
ARCN1 gene, Inflammation	Altered Intercellular Communication	There was no statistically significant difference between patients with mild/moderate inflammation and those with severe COPD.	23055712
Inflammation, Neoplasms	Altered Intercellular Communication	Tumor endothelial inflammation predicts clinical outcome in diverse human cancers.	23056240
Disease, Inflammation, Malignant Neoplasms, Neoplasms	Altered Intercellular Communication	Vascular endothelial cells contribute to the pathogenesis of numerous human diseases by actively regulating the stromal inflammatory response; however, little is known regarding the role of endothelial inflammation in the growth of human tumors and its influence on the prognosis of human cancers.	23056240
Tumor necrosis, Inflammation	Altered Intercellular Communication	Using an experimental model of tumor necrosis factor-alpha (TNF-a)-mediated inflammation, we characterized inflammatory gene expression in immunopurified tumor-associated endothelial cells.	23056240
Neoplasms, Chronic inflammation, Disease	Altered Intercellular Communication	We report that expression of experimentally derived tumor endothelial genes distinguished pathologic tissue specimens from normal controls in several human diseases associated with chronic inflammation.	23056240
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	This study provides the first prognostic cancer gene signature derived from an experimental model of tumor-associated endothelial inflammation.	23056240
Airway structure	Altered Intercellular Communication	Airway inflammation defined by sputum neutrophils showed only a moderate repeatability.	23056262
Epilepsy	Altered Intercellular Communication	Epileptic men may experience hormonal changes that may alter semen quality and sexual function.	23057419
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Elevated markers of systemic inflammation are associated with impaired glucose tolerance and type 2 diabetes mellitus.	23057577
Biliary calculi, Biliary Tract Cancer	Altered Intercellular Communication	Genetic variants in inflammation-related genes have been associated with biliary stones and biliary tract cancers in previous studies.	23057767
Inflammation, Liver and Intrahepatic Biliary Tract Carcinoma, Biliary calculi	Altered Intercellular Communication	These findings provide additional support for the role of inflammation in biliary stones and biliary tract cancer risk and need further validation.	23057767
Chronic sinusitis, Nasal obstruction present finding, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Predicting which chronic rhinosinusitis patients have nasal obstruction due to reversible mucosal inflammation could prevent unnecessary surgery.	23057871
Inflammation, Atherosclerosis	Altered Intercellular Communication	Adipocyte fatty acid-binding protein (A-FABP) is expressed in adipocytes, macrophages and microvascular endothelial cells, and it plays a central role in inflammation, atherosclerosis and metabolic responses.	23057990
Chronic Kidney Diseases	Altered Intercellular Communication	Advanced chronic kidney disease is associated with perturbations in adipose-derived hormones (leptin, adiponectin, and resistin).	23058473
ARCN1 gene, Inflammation, Respiratory Failure	Altered Intercellular Communication	COPD patients who incur higher healthcare resource utilisation show reduced physical activity, increased respiratory failure and increased systemic inflammation.	23058483
Inflammation, Dental Plaque	Altered Intercellular Communication	Sex-related differences in carotid plaque features and inflammation.	23058720
Inflammation, Dental Plaque	Altered Intercellular Communication	Histologic analysis was performed, as well as measurements of plaque composition and inflammation.	23058720
Inflammation, Dental Plaque	Altered Intercellular Communication	Plaque inflammation analysis showed a lower concentration of inflammatory and, in particular, of macrophage foam cells in the plaque cap of women (both P < .05).	23058720
Inflammation, Myositis	Altered Intercellular Communication	Satellite cells and regenerating fibers were significantly increased in s-IBM similar to other inflammatory myopathies and correlated with the intensity of inflammation (R>0.428).	23058947
Inflammation	Altered Intercellular Communication	Our findings indicate profound myo-endothelial remodeling of s-IBM muscle concomitant to inflammation.	23058947
Cancer Pain	Altered Intercellular Communication	A panel of 168 inflammation-related and prostate cancer-related genes was assessed with optimised quantitative PCR to assess biomarkers predictive of survival.	23059047
Inflammation, Neoplasms	Altered Intercellular Communication	NO metabolites, and conventional inflammation and tumor markers were determined.	23059408
Carcinogenesis, Colorectal Carcinoma	Altered Intercellular Communication	Inflammation contributes to the pathogenesis of colorectal cancer (CRC), and cytokine levels are altered during colorectal carcinogenesis.	23059742
Stomach Carcinoma	Altered Intercellular Communication	Inflammation-based prognostic score as a predictor of postoperative gastric cancer recurrence.	23060589
Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	The inflammation-based prognostic score was significantly associated with tumor size and lymph node metastasis.	23060589
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation; from a pathophysiological point of view it involves many components, including mucus hypersecretion, oxidative stress and inflammation.	23061828
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	It has been hypothesized that flavonoids in foods and beverages may reduce cancer risk through antioxidation, inhibition of inflammation, and other antimutagenic and antiproliferative properties.	23061904
Inflammation	Altered Intercellular Communication	IgG4-positive ascending aortic wall was frequent in our study cohort (13%) and revealed aortic inflammation associated with dilatation.	23062412
Inflammation, hepcidin	Altered Intercellular Communication	Preoperative renal function and hemoglobin did not correlate with hepcidin indices whereas plasma markers of inflammation did.	23062413
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation plays a pivotal role in the pathophysiology of cardiovascular disease, (CVD) and leukotrienes may play a role in atherogenesis.	23063168
Inflammation, Malignant neoplasm of endometrium	Altered Intercellular Communication	Chronic inflammation may be an important factor in the initiation and promotion of endometrial cancer.	23063765
Cytomegalovirus Infections, Inflammation, Immune System Diseases	Altered Intercellular Communication	These findings indicate that chronic CMV infection alters the response of aged CD4+ T cells to IL-12 resulting in an increased secretion of IL-21 and that aging affects Tfh cell responses in humans which may contribute to age-associated inflammation and immune dysfunctions.	23064011
Osteogenesis, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	However, the findings appear to suggest that inflammation and fibrosis were associated with ossification.	23064569
Inflammation, Immune System Diseases	Altered Intercellular Communication	IL-9-producing CD4(+) T cells (Th9 cells) have been reported to be involved in inflammation and immune diseases.	23065014
Inflammation, HIV-1 Infection Pathway, HIV-1	Altered Intercellular Communication	Therefore, drivers of immune activation and inflammation in HIV-1 disease may alter monocyte subpopulations and activation phenotype, contributing to a pro-atherothrombotic state that may drive cardiovascular risk in HIV-1 infection.	23065151
Inflammation, hepcidin, Anemia	Altered Intercellular Communication	Hepcidin, an important regulator of iron homeostasis, is suggested to be causally related to anemia of inflammation.	23065507
Inflammation, hepcidin, Anemia, Kidney Diseases	Altered Intercellular Communication	Significantly higher hepcidin levels were found in participants with anemia of inflammation (P<0.01), in participants with anemia of kidney disease (P=0.01), and in participants with unexplained anemia (P=0.01) than in participants without anemia.	23065507
Inflammation, Anemia, hepcidin	Altered Intercellular Communication	In conclusion, older persons with anemia of inflammation have higher hepcidin levels than their counterparts without anemia.	23065507
Inflammation, Hemosiderin, Trauma, Nervous System, Axonal degeneration, Vasculitis, Ischemic	Altered Intercellular Communication	Nerve biopsies (11 upper and 11 lower limbs) showed ischaemic injury (axonal degeneration, multifocal fibre loss 15/22, focal perineurial thickening 16/22, injury neuroma 5/22) and increased inflammation (epineural perivascular inflammation 22/22, haemosiderin deposition 6/22, vessel wall inflammation 14/22 and microvasculitis 5/22).	23065793
Inflammation, Ichthyosis Bullosa of Siemens, NES gene	Altered Intercellular Communication	The pathogenesis of IBS seems to be multifactorial, with the following factors playing a central role in the pathogenesis of IBS: heritability and genetics, dietary/intestinal microbiota, low-grade inflammation, and disturbances in the neuroendocrine system (NES) of the gut.	23066308
NES gene, Inflammation	Altered Intercellular Communication	Alterations in the NES could be the result of one or more of the following: genetic factors, dietary intake, intestinal flora, or low-grade inflammation.	23066308
Pain Distress Question, Inflammation, Fever, CTCAE, Urticaria, Erythema, Dyspnea, Laryngeal Edema	Altered Intercellular Communication	Most clinical manifestations observed were: intense burning pain, urticaria, erythema and inflammation (100%), as well dyspnea with laryngeal edema and fever (19%).	23067562
Necrotizing granulomatous inflammation, Dental Plaque	Altered Intercellular Communication	Increased SUV group had 4 MPM, 5 benign pathology (3 chronic granulomatous inflammation, 2 benign asbestotic plaque).	23067687
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Decreased SUV group all had benign pathology (fibrosis, chronic inflammation, myofibrosis).	23067687
Inflammation, myonecrosis	Altered Intercellular Communication	Influence of platelet reactivity and inflammation on peri-procedural myonecrosis in East Asian patients undergoing elective percutaneous coronary intervention.	23068571
Carcinogenesis, hepatitis A virus	Altered Intercellular Communication	Chronic inflammatory conditions caused by persistent hepatitis virus infections and interferon (IFN)-g-related immunopathology are known to be related to carcinogenesis.	23069256
Inflammation, Rectal Prolapse, Rectal polyp	Altered Intercellular Communication	Mucosal prolapse along with chronic inflammation and tissue embedding artifact were the most common features that led to misdiagnosis in rectal serrated polyps.	23069257
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor alfa (TNF-a) is a cytokine with a central role in inflammation.	23069303
Inflammation, Dermatitis	Altered Intercellular Communication	A punch biopsy specimen demonstrated vacuolar interface dermatitis and lymphohistiocytic perivascular inflammation.	23069957
Inflammatory abnormality of the eye, Ocular Toxoplasmosis	Altered Intercellular Communication	Ocular inflammation does not mean reactivation of ocular toxoplasmosis.	23070707
Chronic liver disease, Portal inflammation	Altered Intercellular Communication	Six cases were associated with chronic liver disease and the remaining 4 cases showed mild fatty change in the parenchyma and/or minimal to mild portal inflammation.	23073321
Hyperglycemia, Inflammation, Complications of Diabetes Mellitus	Altered Intercellular Communication	Glucose ingestion-induced hyperglycemia has been known to induce inflammation, which is related to the pathogenesis of diabetic complications.	23073386
Inflammation, Complications of Diabetes Mellitus	Altered Intercellular Communication	We believe that these results will provide some basic insight into the role of leukocytes in hyperglycemia-induced inflammation and the pathogenesis of diabetic complications.	23073386
Inflammation, Osteopenia	Altered Intercellular Communication	A sufficient width of keratinized peri-implant mucosa is important to prevent peri-implant bone loss and inflammation.	23075057
Inflammation	Altered Intercellular Communication	Interleukin-18 (IL-18) is a member of the IL-1 cytokine family that affects chronic inflammation.	23075512
Inflammation, Craniosynostosis	Altered Intercellular Communication	These results suggest that the pro-inflammatory effect of IL-18 released by danger signals may be involved in the pathogenesis of CRS, which includes eosinophilic inflammation and NP formation, via the augmentation of both Th2- and Th1-associated cytokine production.	23075512
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Red blood cell distribution width (RDW) is a novel prognostic marker that reflects oxidative stress and chronic inflammation in patients with cardiovascular disease.	23075764
vascular inflammations, Diabetes Mellitus, Atherosclerosis	Altered Intercellular Communication	Diabetes mellitus increases oxidative stress and vascular inflammation, which accelerate atherosclerosis.	23075764
Fibrosis Assessment, Hepatitis, Chronic	Altered Intercellular Communication	Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice.	23076146
Tissue damage, Inflammation, Virus Diseases	Altered Intercellular Communication	The human body has a remarkable ability to regulate inflammation, a biophysical response triggered by virus infection and tissue damage.	23076146
Inflammation	Altered Intercellular Communication	Sirt6 is critical for metabolism and lifespan; however, its role in inflammation is unknown.	23076146
Hepatitis, Chronic	Altered Intercellular Communication	Here we show that Sirt6-null (Sirt6(-/-)) mice developed chronic liver inflammation starting at ~2 months of age, and all animals were affected by 7-8 months of age.	23076146
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Deletion of Sirt6 in T cells or myeloid-derived cells was sufficient to induce liver inflammation and fibrosis, albeit to a lesser degree than that in the global Sirt6(-/-) mice, suggesting that Sirt6 deficiency in the immune cells is the cause.	23076146
Inflammation, Anemia	Altered Intercellular Communication	Concurrent inflammation or anemia at the time of PET/computed tomography (CT) could be one of several causes of diffuse splenic (18)F-fluorodeoxyglucose ((18)F-FDG) uptake.	23076270
ARTERIAL TORTUOSITY SYNDROME, Inflammation, Venous Stroke, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is an important pathophysiological basis of atherothrombotic stroke (ATS), and inflammation plays a significant role in atherosclerosis formation.	23076369
Inflammation, Necrosis	Altered Intercellular Communication	Biomarkers of necrosis and inflammation have been found raised after radiofrequency ablation (RF).	23078110
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Interleukin-29 modulates proinflammatory cytokine production in synovial inflammation of rheumatoid arthritis.	23078630
Inflammation, Sepsis, Tissue damage, Single organ dysfunction, GTF2A1L wt Allele, Liver Failure, Acute	Altered Intercellular Communication	Systemic inflammation and susceptibility to developing sepsis is common in acute liver failure (ALF) resulting in tissue damage and organ failure.	23079896
Inflammation, Ectropion	Altered Intercellular Communication	Eye-washing methods without eyelid eversion are more effective in reducing conjunctival bacteria before surgery and anterior chamber inflammation after surgery than those with eyelid eversion.	23080269
Cessation of life, Steatohepatitis, Liver damage, Inflammation	Altered Intercellular Communication	Aging does not promote the development of hepatic steatosis but leads to increased hepatocellular injury and inflammation that may be due in part to sensitization to the Fas death pathway and increased M1 macrophage polarization.	23081825
Inflammation, Glucocorticoid deficiency with achalasia, Aortic Aneurysm, Abdominal, Rupture	Altered Intercellular Communication	Mycotic abdominal aortic aneurysms (AAAs) are a clinical challenge for vascular surgeons due to their critical location, surrounding inflammation, risk of rupture, and danger of reinfection following treatment.	23081891
Abdomen, Acute, Chief complaint (finding), Acute inflammation, Anisakiasis	Altered Intercellular Communication	In patients with a recent history of eating raw marine fish presenting with acute onset of abdominal complaints and CT features of acute small bowel inflammation the possibility of anisakiasis should be considered in the differential diagnosis of acute abdominal syndromes.	23082711
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Chronic asymptomatic inflammation of the prostate type IV and carcinoma of the prostate: is there a correlation?	23082817
Inflammation	Altered Intercellular Communication	Chronic inflammation was verified in 43.86% of the RPE group, compared to 70.74% of the BPH group (p < 0.001).	23082817
TNM Staging System, Inflammation, Neoplasms	Altered Intercellular Communication	Gleason score distribution (5-9) and tumour stage (TNM) were similar in the inflammation and non-inflammation groups (p < 0.99, p < 0.21).	23082817
Prostate carcinoma, prostatitis	Altered Intercellular Communication	No significant correlation between chronic prostatic inflammation and carcinoma of the prostate was detected.	23082817
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The NLR, an index of systemic inflammation, is associated with outcome in several cancer types.	23083797
Inflammation, Impaired lung function	Altered Intercellular Communication	Systemic inflammation is associated with impaired lung function.	23083841
Inflammation, Thromboembolic stroke	Altered Intercellular Communication	Higher NLR, an emerging marker of inflammation, is associated with thromboembolic stroke in non-valvular AF patients.	23084070
Intraocular inflammation	Altered Intercellular Communication	To describe an outbreak of intraocular inflammation caused by endotoxin-contaminated counterfeit bevacizumab in China.	23084126
Intraocular inflammation	Altered Intercellular Communication	The medical records and microbiology results of patients who presented with intraocular inflammation after injection with intravitreal counterfeit bevacizumab were reviewed.	23084126
Intraocular inflammation, Inflammation	Altered Intercellular Communication	The incidence of intraocular inflammation, results of pathogen cultures, and clinical features of inflammation.	23084126
Hypopyon, Vitreous inflammatory cells	Altered Intercellular Communication	Twenty-one patients with hypopyon and significant vitreous inflammation underwent vitrectomy.	23084126
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Chronic inflammation has been associated with endothelial dysfunction and altered coagulation status.	23085092
Inflammation	Altered Intercellular Communication	In cardiac patients positive affect has found to be associated with improved clinical outcomes, with reduced inflammation being one of the potential mechanisms responsible.	23085133
Inflammation, Heart failure	Altered Intercellular Communication	Positive affect is associated with reduced inflammation in patients with heart failure.	23085133
Inflammation, Brain Injuries, Osteochondritis Dissecans, Postoperative cognitive dysfunction	Altered Intercellular Communication	We hypothesized that different patterns of biomarkers of brain injury and inflammation exist in aged patients with postoperative cognitive dysfunction (POCD) after total hip-replacement with spinal anesthesia.	23085747
Inflammation, Carcinogenesis, Stomach Carcinoma	Altered Intercellular Communication	Chronic inflammation and gastric carcinogenesis show a close association, so gene polymorphisms that modify the intensity of the inflammatory response may contribute to variations in gastric cancer risk.	23086128
Pain Distress Question, Inflammation	Altered Intercellular Communication	Ibuprofen is a non-selective cyclo-oxygenase (COX)-1/COX-2 inhibitor used to treat pain conditions and inflammation.	23086696
Inflammation, Paraproteinemias, Autoinflammatory disorder, Urticaria	Altered Intercellular Communication	Schnitzler's syndrome is a chronic disabling autoinflammatory disorder, characterised by chronic urticaria, paraproteinemia and systemic inflammation.	23087179
Inflammation, acute diverticulitis	Altered Intercellular Communication	The value of inflammation markers and body temperature in acute diverticulitis.	23088216
Inflammation, Atherosclerosis	Altered Intercellular Communication	Fish consumption, omega-3 fatty acids, and environmental contaminants in relation to low-grade inflammation and early atherosclerosis.	23089109
Inflammation, Atherosclerosis	Altered Intercellular Communication	Our aim was to elucidate the associations of fish consumption, omega-3 PUFAs, environmental contaminants with low-grade inflammation, early atherosclerosis, and traditional CVD risk factors.	23089109
Inflammation, Depressed mood, Depression, CTCAE, Metabolic Syndrome X	Altered Intercellular Communication	Evidence for a differential role of HPA-axis function, inflammation and metabolic syndrome in melancholic versus atypical depression.	23089630
Mastitis, Inflammation, Caseous necrosis	Altered Intercellular Communication	Histopathological examination revealed features of mastitis with epithelioid histiocytes and Langhans giant cells and was characterized by the presence of caseous necrosis which suggested tuberculous inflammation.	23089809
Hypermobility, Inflammation	Altered Intercellular Communication	Further studies demonstrated hypermobility with adjacent soft-tissue reactivity and inflammation surrounding the right T5 transpedicle screw.	23089930
Inflammation	Altered Intercellular Communication	Compared to subcutaneous fat, visceral fat is more metabolically active, leading to chronic inflammation and tumorigenesis.	23090279
Refractory anemias	Altered Intercellular Communication	HR-pQCT provides new insight into inflammation-associated bone fragility in RA.	23090909
Tissue damage, Inflammation	Altered Intercellular Communication	"Surgical stress response" is tissue damage postsurgery, leading to a systemic response (inflammation, sympathetic upregulation, and release of vasoactive chemicals), which is typically measured by C-reactive protein (CRP).	23091271
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	Activation of the innate immune system and subsequent chronic low-grade inflammation are thought to be involved in the pathogenesis of atherosclerosis and type 2 diabetes.	23091345
Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is an inflammatory condition and increased blood levels of inflammatory biomarkers have been observed in acute coronary syndromes.	23091596
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Excess visceral fat causes local chronic low-grade inflammation and dysregulation of adipocytokines, which contribute in the pathogenesis of the metabolic syndrome.	23091619
Inflammation, Atherosclerosis	Altered Intercellular Communication	Assay panels for biomarkers associated with atherosclerosis biology (inflammation, angiogenesis, apoptosis, chemotaxis, etc.)	23092312
Aneurysm, CDIPT gene, Fever, CTCAE, Inflammation	Altered Intercellular Communication	In patients undergoing endovascular aneurysm repair (EVAR), the postimplantation syndrome (PIS), comprising fever and inflammation, occurs frequently.	23092643
CLU protein, human, Ischemia, Inflammation	Altered Intercellular Communication	We hypothesise that severe ischaemia and/or prolonged inflammation in CLI might lead to a paradoxical attenuation in the proinflammatory membrane pattern of circulating mononuclear cells, possibly hindering an adequate regulatory function of mDCs and pDCs and favouring the progression of disease.	23093299
Impaired T cell function	Altered Intercellular Communication	In conclusion, common variation in MAP4K4 is associated with insulin resistance and b-cell dysfunction, possibly via this gene's role in inflammatory signalling.	23094072
Inflammation, Metabolic Diseases, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	Protein-calorie malnutrition as well as systemic inflammation and metabolic disorders are common among patients with chronic renal failure undergoing renal replacement therapy (hemodialysis), which contributes to their morbidity and mortality.	23094520
Erectile dysfunction	Altered Intercellular Communication	Erectile dysfunctions (EDs) are in part caused by hormonal causes; but in men over 65 years of age, testosterone deficiency seems to play an important role.	23094956
Inflammation, Spondylitis, Pain Distress Question	Altered Intercellular Communication	At week 12 the Bath Ankylosing Spondylitis Disease activity spinal inflammation score decreased by 65% (P <0.001), the back pain score decreased by 50% (P <0.005), the Bath AS Functional Index (BASFI) score decreased by 47% (P <0.02), while the Childhood Health Assessment Questionnaire-Disability Index (CHAQ-DI) score improved by 65% (P <0.005).	23095307
Inflammation	Altered Intercellular Communication	Rebound of choroidal thickening was observed in three patients (five eyes) during corticosteroid tapering in the absence of other evidence of increased inflammation.	23095726
Choroiditis	Altered Intercellular Communication	Choroidal thickness as measured by EDI-OCT may serve as a marker for degree of choroidal inflammation in acute VKH disease.	23095726
Diabetic Retinopathy, Inflammatory abnormality of the eye	Altered Intercellular Communication	The pathogenesis of diabetic retinopathy has been suggested to be associated with ocular inflammation.	23095769
Tissue damage	Altered Intercellular Communication	Interleukins, interferons and oxidative DNA products are important biomarkers assessing the inflammations and tissue damages caused by toxic materials in the body.	23096020
Inflammation	Altered Intercellular Communication	Cytokines, such as interleukin 10 (IL10), play an important role in the process of inflammation.	23096091
ARCN1 gene, Inflammation, exacerbation acute	Altered Intercellular Communication	This raise may be related directly to COPD and its associated systemic inflammation or secondary to other factors such as smoking status, disease severity, acute exacerbations, or associated complications.	23096661
Sepsis, Communicable Diseases, Inflammation	Altered Intercellular Communication	In addition to their beneficial effects against infection, NK cells may play a detrimental role during systemic inflammation, causing lethality during sepsis.	23098236
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	[The role of markers of inflammation in assessment of prognosis in patients with ST-elevation myocardial infarction combined with disturbances of carbohydrate metabolism].	23098394
Inflammation, Low Grade Squamous Intraepithelial Neoplasia	Altered Intercellular Communication	MLBC was more sensitive in diagnosis of LSIL and more specific in the diagnosis of inflammation.	23098448
Inflammation, Apolipoprotein E	Altered Intercellular Communication	Apolipoprotein E (ApoE) is a multifunctional protein playing both a key role in the metabolism of cholesterol and triglycerides, and in tissue repair and inflammation.	23098561
Inflammation	Altered Intercellular Communication	In the following 12 months he required 5 major surgeries due to a process of systematic inflammation/infection throughout different locations of the DBS system.	23098765
Inflammation, Impaired cognition, Abnormality of the vasculature	Altered Intercellular Communication	Given these results, there is a possibility that inflammation and cerebrovascular abnormalities might be the cause of cognitive decline in this model.	23099816
Pneumonitis	Altered Intercellular Communication	Recovery of neutrophil apoptosis by ectoine: a new strategy against lung inflammation.	23100492
Pneumonitis	Altered Intercellular Communication	The life span of neutrophilic granulocytes has a determining impact on the intensity and duration of neutrophil driven lung inflammation.	23100492
Pneumonitis	Altered Intercellular Communication	Neutrophilic lung inflammation induced by single or multiple expositions of animals to environmental particles was reduced after the therapeutic intervention with ectoine.	23100492
Airway structure	Altered Intercellular Communication	Are these results related to changes in distinct markers of airway inflammation and extracellular remodelling?	23100503
Inflammation, Observation Method - Coagulation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Association of physical activity with insulin resistance, subclinical inflammation, coagulation, and fibrinolytic biomarkers among population at high risk for type 2 diabetes.	23101283
Inflammation, Observation Method - Coagulation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	TO investigate the association of physical activity with insulin resistance and biomarkers of inflammation, coagulation, and fibrinolysis in a population at high risk for type 2 diabetes.	23101283
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study.	23101478
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Mechanisms involved in metabolic syndrome (MetS) development include insulin resistance, weight regulation, inflammation and lipid metabolism.	23101478
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	The groups of inflammation and lipid SNPs were neither associated with presence of MetS nor with MetS score.	23101478
Ichthyosis Bullosa of Siemens, Functional disorder, Gastrointestinal inflammation, Irritable Bowel Syndrome	Altered Intercellular Communication	The traditional classification of irritable bowel syndrome (IBS) as a functional disorder has been challenged in recent years by evidence of ongoing low-grade gastrointestinal tract inflammation.	23102771
Inflammation, Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	Inflammation may alter gastrointestinal motility and thus be central to the pathogenesis of IBS.	23102771
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Is increased red cell distribution width (RDW) indicating the inflammation in Alzheimer's disease (AD)?	23103090
Inflammation, Data types - Address	Altered Intercellular Communication	Increasing evidence indicates that inflammation has a substantial role in the pathogenesis and progression of AD.	23103090
Inflammation, Data types - Address	Altered Intercellular Communication	Whereas elevated RDW value is usually considered as a novel biomarker of inflammation, the results of our study may support the role of inflammation in pathophysiology of AD.	23103090
Communicable Diseases, Inflammation, Leprosy	Altered Intercellular Communication	Identification of IL18RAP/IL18R1 and IL12B as leprosy risk genes demonstrates shared pathogenesis between inflammation and infectious diseases.	23103228
Uremia, Inflammation, Diabetic Angiopathies, Diabetes Mellitus	Altered Intercellular Communication	Carbonylation of the protein amino, guanidine, and thiol groups with a-oxoaldehydes (which are produced in higher quantities in diabetes, uremia, oxidative stress, aging, and inflammation) is one of the important causes of vascular complications.	23103397
Inflammation	Altered Intercellular Communication	Furthermore, MMP-2, MMP-9 (p < 0.04) and elastase in group B showed faster and greater decrease in levels, compared with group A, indicating a faster and superior reduction of inflammation.	23103485
Refractory anemias, Inflammation	Altered Intercellular Communication	For optimal RA management, the current recommendation is to adapt DMARD therapy to the level of inflammation and not only of patient complaints.	23104976
Tissue damage, Inflammation, Hyperpigmentation	Altered Intercellular Communication	Inflammation drives wound hyperpigmentation in zebrafish by recruiting pigment cells to sites of tissue damage.	23104990
Inflammation	Altered Intercellular Communication	We discuss the theoretical possibility that foreskin inflammation compromises the mucosal/epithelial barrier, thus playing a role in disease transmission.	23106553
Region of nasal process, Ear Inflammation, allergic inflammation, IL13 gene, effusion	Altered Intercellular Communication	Otitis media with effusion is closely associated with allergic rhinitis presumably caused by allergic inflammation, but not mechanical nasal mucosal swelling.	23106661
Malignant neoplasm of esophagus, Inflammation, Primary malignant neoplasm, Cancer-Related Death	Altered Intercellular Communication	Esophageal cancer is the seventh leading cause of cancer death in males in USA, and there is a strong link has been demonstrated between inflammation and esophageal cancer, interleukin (IL)-32 is a recently described pro-inflammatory cytokine characterized by the induction of nuclear factor NF-kB activation, the p38MAPK also plays an important role in key cellular processes related to inflammation and cancer.	23107826
Inflammation, Ischemia	Altered Intercellular Communication	We have found that oxidative stress and inflammation were increased and antioxidative defense was decreased, which resulted in increased levels of IMA, a biomarker of ischemia, in obese subjects.	23108391
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Biopsy samples from 18 patients (33%) showed nearly normal histology with no inflammation, fibrosis, or steatosis.	23109058
Inflammation, Fibrosis Assessment, Cholestasis	Altered Intercellular Communication	The fibrosis stage correlated negatively with serum prealbumin levels (r = -0.364, P = 0.007) and positively with chronic cholestasis (cytokeratin 7 staining; r = 0.529, P < 0.001) and portal inflammation (r = 0.350, P = 0.01).	23109058
Herpes Zoster Ophthalmicus, Orbital Myositis, Optic Neuritis	Altered Intercellular Communication	Painful ophthalmoplegia with simultaneous orbital myositis, optic and oculomotor nerve inflammation and trigeminal nucleus involvement in a patient with herpes zoster ophthalmicus.	23109414
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The role of metabolic syndrome, adiposity, and inflammation in physical performance in the Health ABC Study.	23109678
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Metabolic syndrome (MetS) and functional limitation have been linked, but whether and how specific components of MetS and associated factors, such as inflammation, drive this relationship is unknown.	23109678
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Recently, it has been hypothesized that inflammasomes could have a crucial role in the host response to silica and recent studies show that the inflammasome contributes to inflammation and pulmonary fibrosis.	23110140
Inflammation, Traumatic injury	Altered Intercellular Communication	The presence of thick attached keratinized tissue around implants may constitute a protective factor against marginal inflammation or trauma.	23110330
Congenital Abnormality	Altered Intercellular Communication	No signs of hormonal deficency was shown authorizing us to approach the disease as a congenital malformation due to an abnormality of intrauterine development.	23110911
Inflammation, Damage, Rheumatoid Arthritis, MTTP wt Allele	Altered Intercellular Communication	Low-field MRI versus ultrasound: which is more sensitive in detecting inflammation and bone damage in MCP and MTP joints in mild or moderate rheumatoid arthritis?	23111117
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The aim of the present paper is to determine if the ultrasound of hands and feet is comparable to the MRI of the dominant hand to detect erosive disease and inflammation in mild or moderate rheumatoid arthritis (RA).	23111117
Lymphoproliferative Disorders, Orbital Pseudotumor	Altered Intercellular Communication	To determine whether serologic factors correlate with early relapse in cases of IgG4-related orbital inflammation, a lymphoproliferative disorder.	23111178
Rheumatoid Factor, Orbital Pseudotumor	Altered Intercellular Communication	The serum rheumatoid factor level may correlate with proliferative activity in IgG4-related orbital inflammation.	23111178
Inflammation, Necrosis	Altered Intercellular Communication	Adequate biopsy is required for a diagnosis because this lymphoma frequently coexists with large amount of necrosis and inflammation.	23111392
HD Term Type, Inflammation	Altered Intercellular Communication	FID is present in a substantial proportion of patients on HD, who thus should be screened for reversible causes of inflammation.	23111696
Uremia, Inflammation	Altered Intercellular Communication	Thus, the higher concentration of cC characteristic for uremic patients may modulate acute inflammation through maintaining PMN longevity and inhibiting their respiratory burst and proinflammatory cytokine-related changes in cC release from PMNs.	23111743
Familial benign pemphigus, Inflammation, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	PCR was negative in HHD without inflammation while it was positive in 10 subjects with myocarditis (enterovirus in 3 cases, adenovirus 4, influenza virus 3).	23112000
Granulomatous inflammation	Altered Intercellular Communication	Histopathology of tracheobronchial nodules and bronchial mucosa biopsy specimen both showed granulomatous inflammation with proliferation of capillaries and inflammatory cells.	23112563
Hepatitis	Altered Intercellular Communication	Galectin-9 was detectable at increased concentrations in the sera of patients with active CHB-related liver inflammation (p = 0.02) and was strongly expressed by Kupffer cells within the liver sinusoidal network.	23112829
Immunologic Deficiency Syndromes, Inflammation, Traumatic injury	Altered Intercellular Communication	Authors draw attention to possibility of other etiological agents for BCC like local trauma, ageing, ionizing radiation, arsenic, chronic inflammation, and immune deficiency.	23113607
Arthritis	Altered Intercellular Communication	Maori and Pacific participants had earlier age of onset (by 9 years), higher flare frequency and more features of joint inflammation.	23114632
Inflammation	Altered Intercellular Communication	A dysfunction of the rich neural plexus around the ductules may play a role in the development of dacryops in conjunction with periductular inflammation and induced scarring.	23114708
Inflammation, Malignant neoplasm of gastrointestinal tract	Altered Intercellular Communication	Nutritional status, systemic inflammation and prognosis of patients with gastrointestinal cancer.	23114934
Communicable Diseases, Inflammation	Altered Intercellular Communication	High prevalence values were found for systemic inflammation (73%), a greater risk of infectious and/or inflammatory complication (43%) and worse prognosis (50%).	23114934
Inflammation, Malignant neoplasm of gastrointestinal tract	Altered Intercellular Communication	Nutritional status is related to inflammation markers and prognosis in patients with gastrointestinal cancer.	23114934
Inflammation, Nephrolithiasis	Altered Intercellular Communication	108 patients aged from 18 to 59 years (mean age - 40.26 +/- 10.09 years) with secondary CPN against dysmetabolic nephropathy and nephrolithiasis in a phase of active inflammation were observed.	23116015
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Dispositional hostility as measured by the Cook Medley Hostility (Ho) Scale has been associated with inflammation and cardiovascular disease (CVD) risk.	23116190
Colorectal Carcinoma	Altered Intercellular Communication	Inflammation-based prognostic system predicts survival after surgery for stage IV colorectal cancer.	23116639
Inflammation Mediators	Altered Intercellular Communication	Future research using these techniques will aid further understanding of the inflammation-mediated bony changes associated with development and progression of CN and other diseases.	23117208
Demographics Domain, Congenital Abnormality, Diabetes Mellitus, Ulceration, CTCAE, Neurogenic arthropathy, Peripheral Neuropathy	Altered Intercellular Communication	Charcot neuroarthropathy (CN), an inflammatory condition characterized by rapid and progressive destruction of pedal bones and joints, often leads to deformity and ulceration in individuals with diabetes mellitus (DM) and peripheral neuropathy (PN).	23117208
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The interleukin-6 (IL-6) pathway is one of the mechanisms that link inflammation and angiogenesis with malignancy.	23117246
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Since nuclear factor-kB (NF-kB) is a potential sign for inflammation, NF-kB has been associated with the progression of disease in various types of cancer.	23117246
Cataract, Inflammation	Altered Intercellular Communication	Additional complications observed were cataract progression requiring surgery (42%), persistent intraocular pressure elevation (36%), and transient inflammation (32%).	23117281
Neoplastic, Fibrosis Assessment, Inflammation, Anthracosis	Altered Intercellular Communication	A final diagnosis of fibrosis associated with anthracosis was made, and neither active inflammation nor neoplastic lesion was not demonstrated.	23117360
Damage	Altered Intercellular Communication	Inflammation-induced and stress-related cardiac damage are increasingly recognized in patients with critical illness.	23117374
Pain Distress Question, Swelling, Inflammation	Altered Intercellular Communication	Pain, swelling and inflammation are expected during the recovery from total knee arthroplasty (TKA) surgery.	23118406
Inflammation	Altered Intercellular Communication	Inflammation is part of a complex biological response of vascular tissue to pathogens or damaged cells.	23119050
Inflammation, Hypoxia	Altered Intercellular Communication	Hypoxia and p38-MAPK are associated with inflammation, and hypoxia inducible factor 1 (HIF-1) has been detected in inflamed tissues.	23119050
Inflammation, Primary malignant neoplasm, Non-Cancer Related Death	Altered Intercellular Communication	After endoscopy each patient was assigned into one of two groups: (1) non-cancer, including inflammation; (2) cancer group.	23119113
Inflammation, Esophageal carcinoma	Altered Intercellular Communication	The AFI displayed mucosal inflammation and carcinomas of esophagus and stomach as dark red color, the normal mucosa background was displayed as light green.	23119113
Inflammation, Hepatitis	Altered Intercellular Communication	The pattern of cytokines and chemokines in sera was linked to HBV viral load and was consistent with the level of inflammation during chronic hepatitis.	23121366
Pulmonary Emphysema, Inflammation, Atelectasis, Hyperemia	Altered Intercellular Communication	Early emphysema is associated with elevated tissue volume and FTV, consistent with hyperemia, inflammation or atelectasis.	23122057
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Diagnostic performance of conventional diffusion weighted imaging and diffusion tensor imaging for the liver fibrosis and inflammation.	23122674
Compact Disk Interactive, Inflammation, Fibrosis, Liver	Altered Intercellular Communication	To evaluate the diagnostic accuracy of liver apparent diffusion coefficient (ADC) measured with conventional diffusion-weighted imaging (CDI) and diffusion tensor imaging (DTI) for the diagnosis of liver fibrosis and inflammation.	23122674
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histopathologically, fibrosis of the liver parenchyma was classified with the use of a 5-point scale (0-4) and inflammation was classified with use of a 4-point scale (0-3) in accordance with the METAVIR score.	23122674
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Quantitatively, signal intensity and the ADCs of the liver parenchyma were compared between patients stratified by fibrosis stage and inflammation grade.	23122674
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver ADC values inversely correlated with fibrosis and inflammation but there was only statistically significant for inflammatory grading.	23122674
Compact Disk Interactive, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	CDI performed better than DTI for the diagnosis of fibrosis and inflammation.	23122674
Inflammation, NEUROTICISM, GDC Comorbidity Terminology, Conscious, Obesity	Altered Intercellular Communication	Adjustment for health behaviors diminished the magnitude of this association but did not eliminate it, suggesting that lower comorbid conditions and obesity may partly explain the lower inflammation of those high in both Conscientiousness and Neuroticism.	23123863
Inflammation	Altered Intercellular Communication	Using personality to identify those at risk may lead to greater personalization in the prevention and remediation of chronic inflammation.	23123863
Refractory anemias, Rheumatoid Arthritis, Inflammation, Pain Distress Question	Altered Intercellular Communication	Among rheumatoid arthritis (RA) patients, the intensity of pain may be out of proportion to the severity of peripheral inflammation.	23124650
Refractory anemias, Inflammation, Dyssomnias	Altered Intercellular Communication	Sleep problems, mental health, and inflammation were assessed as mediators of the relationship between RA and QST outcomes.	23124650
Inflammation	Altered Intercellular Communication	It is hypothesized that their appearance could be provoked by either increased erythropoiesis or bone marrow micro-architectural damage mostly caused by inflammation and/or decreased tissue oxygenation.	23126050
Inflammation, Primary malignant neoplasm, Communicable Diseases, Rheumatoid Arthritis, Reactive systemic amyloidosis	Altered Intercellular Communication	Secondary amyloidosis (AA) is a rare but serious complication that appears in the context of cancer, chronic inflammation, and chronic infectious disease, including rheumatoid arthritis.	23126056
ARCN1 gene, Inflammation, Lung Injury	Altered Intercellular Communication	Increased CD4(+)IL-17(+) cell number in lung tissue is involved in chronic inflammation of the lungs and parallels lung injury aggravation in COPD patients and in smokers without airway limitations.	23127823
Communicable Diseases, Inflammation	Altered Intercellular Communication	Any kind of infection or inflammation was an exclusion criterion.	23128367
Retinitis	Altered Intercellular Communication	These findings suggest that PEDF accelerated the recovery of tear secretion and also prevented neurotrophic keratouveitis and vitreoretinal inflammation.	23128960
Inflammation, Takayasu Arteritis	Altered Intercellular Communication	Takayasu arteriitis (TA) was clinically diagnosed and confirmed by MR angiography and FDG-PET scan showing inflammation of the aortic arch and the left subclavian artery.	23129041
Inflammation	Altered Intercellular Communication	Immunosuppression with glucocorticoids and methotrexate resulted in immediate clinical improvement and normalization of systemic markers of inflammation.	23129041
Inflammation	Altered Intercellular Communication	This case shows that vascular progress in TA patients may occur even when systemic inflammation is controlled, therefore patients have to be carefully observed for new vascular manifestations.	23129041
Electrocardiogram: myocardial infarction (finding), Depression, CTCAE	Altered Intercellular Communication	Disturbance of serotonergic neurotransmission in patients with postmyocardial infarction and depression.	23129293
ARCN1 gene, Inflammation, Sarcopenia, Osteopenia	Altered Intercellular Communication	Comorbidities of COPD include increased risk of cardiovascular (CV) disease, loss of bone mineral density (BMD) and loss of skeletal muscle mass and function, all linked to systemic inflammation.	23129800
Arterial Stiffness, Inflammation, Bronchiectasis	Altered Intercellular Communication	Patients with bronchiectasis had increased arterial stiffness (an indicator of increased CV risk), increased inflammation, reduced exercise capacity and bone thinning.	23129800
Inflammation	Altered Intercellular Communication	Survivors with MS have features of inflammation and prothrombotic state, increased carotid artery intima-media thickness.	23131388
Inflammation, Malnutrition, Xerostomia, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease is associated with inflammation, oxidative stress, malnutrition, poor oral health, and mouth dryness.	23131570
Inflammation, Osteoporosis	Altered Intercellular Communication	In conclusion, variation in inflammatory genes CIITA, CLEC-16A and INFG appear to contribute to bone phenotypes in elderly women and suggest a role for low-grade inflammation and MHC class II expression for osteoporosis pathogenesis.	23133532
Inflammation, Helicobacter pylori, Dysplasia, Communicable Diseases, Pancreatic aplasia, Intestinal metaplasia	Altered Intercellular Communication	The maximal lengths of CLE and superficial esophageal glands (SEG) and the presence or absence of chronic inflammation (CI), lymphoid follicles (LF), Helicobacter pylori (H. pylori) infection, intestinal metaplasia (IM), pancreatic metaplasia (PM) and dysplasia were analyzed and compared with those in the adjacent proximal gastric mucosa.	23134360
Cerebral Amyloid Angiopathy, Inflammation, Pathology, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) and cerebral amyloid angiopathy (CAA) are two common pathologies associated with b-amyloid (Ab) accumulation and inflammation in the brain; neither is well understood.	23134465
Communicable Diseases, Inflammation, Malignant Neoplasms, Disturbance	Altered Intercellular Communication	On the other hand, C-reactive protein (CRP) and serum amyloid A (SAA) are acute inflammatory biomarkers that increase in various conditions including infection, inflammation, malignancy and tissue disturbance.	23135313
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is a chronic condition characterised by the relapsing inflammation despite previous endoscopic and histological healing.	23135761
Inflammation, Neuropathy, Edema, Strangulation, Palsy	Altered Intercellular Communication	Bell palsy is considered to be an entrapment neuropathy resulting from inflammation, edema, and strangulation.	23136321
Stomach Carcinoma, Communicable Diseases, Helicobacter pylori, Inflammation	Altered Intercellular Communication	Gastric cancer is supposed to be a result of inflammation induced by Helicobacter pylori (H. pylori) infection.	23136938
Chronic neuropathic pain	Altered Intercellular Communication	Mediators produced by glial and immune cells are now believed to modulate neuronal transmission and promote chronic neuropathic pain.	23136965
Pneumonitis	Altered Intercellular Communication	Destructive pulmonary inflammation can leave patients with only a single functional lung, resulting in anatomical and physiological changes that may interfere with subsequent cardiac surgeries.	23137038
Inflammation, Inflammatory disorder	Altered Intercellular Communication	High-mobility group box-1 (HMGB1) is regarded as a central mediator of inflammation and involved in many inflammatory diseases.	23137435
Cessation of life, Inflammation	Altered Intercellular Communication	The p38 mitogen-activated protein kinase (MAPK) is a nexus point in inflammation, sensing, and stimulating cytokine production and driving cell migration and death.	23137494
Inflammation, Acute myocardial infarction, Atherosclerosis	Altered Intercellular Communication	The complement system is an important mediator of inflammation, which plays a pivotal role in atherosclerosis and acute myocardial infarction (AMI).	23137511
Inflammation, Hyperplasia, immunoglobulin A	Altered Intercellular Communication	Histology revealed eosinophilic inflammation with microabscesses and pseudoepitheliomatous hyperplasia, but she was negative on direct immunofluorescence for IgA, IgG and C3.	23138121
Metabolic Syndrome X, Cardiovascular Diseases, Dyslipidemias, ETV3 wt Allele, Diabetes Mellitus, Obesity, Hypertension, CTCAE	Altered Intercellular Communication	These abnormalities include obesity, dyslipidemia, hypertension, and insulin resistance and are collectively known as metabolic syndrome (MetS), a low-grade, systemic, inflammatory condition associated with an increased risk of cardiovascular disease, diabetes, and other adverse health outcomes.	23138631
Inflammation	Altered Intercellular Communication	In segments with acute inflammation, the mean MTR was slightly smaller (22.9 +- 2.2 %).	23138635
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Accumulation of amyloid-b (Ab) and neurofibrillary tangles in the brain, inflammation and synaptic and neuronal loss are some of the major neuropathological hallmarks of Alzheimer's disease (AD).	23138650
Extrahepatic Cholangiocarcinoma	Altered Intercellular Communication	Inflammation-based prognostic score is a useful predictor of postoperative outcome in patients with extrahepatic cholangiocarcinoma.	23138964
Malignant Neoplasms	Altered Intercellular Communication	Recent studies have revealed that the Glasgow prognostic score (GPS), an inflammation-based prognostic score, is useful for predicting outcome in a variety of cancers.	23138964
Uremia, Inflammation, Immune System Diseases	Altered Intercellular Communication	Pathophysiologically, the immune dysfunction, telomere attrition and the presence of low-grade inflammation in uremic patients also show parallels with the aging process.	23139404
Inflammation, Hematoma, SDSL gene	Altered Intercellular Communication	A considerable body of evidence indicates that inflammation and angiogenesis play a significant role in the development and progression of chronic subdural hematoma (CSDH).	23140147
Inflammation, Hematoma, SDSL gene	Altered Intercellular Communication	Given previous evidence indicating a role for PlGF in promoting angiogenesis, inflammatory cell chemotaxis, and stimulation, as well as its ability to amplify VEGF-driven signaling under conditions favoring pathological angiogenesis, enhanced expression of PlGF in hematoma fluid suggests the involvement of this factor in the mechanisms of inflammation and angiogenesis in CSDH.	23140147
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Serum C-reactive protein (CRP) is one particular marker of systemic inflammation, and an elevated CRP level is associated with poor outcome in various malignancies.	23141922
ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by pulmonary inflammation that persists after the cessation of smoking.	23142009
ARCN1 gene, Inflammation	Altered Intercellular Communication	T cells have a major role in driving inflammation in patients with COPD and are activated by specific antigens to produce mediators, such as cytokines.	23142009
ARCN1 gene, Inflammation	Altered Intercellular Communication	This proinflammatory profibrotic response might be a key cause of inflammation in patients with COPD and has implications for treatment.	23142009
Cessation of life, Inflammation, ARCN1 gene	Altered Intercellular Communication	Statins, systemic inflammation and risk of death in COPD: the Rotterdam study.	23142156
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Galectin-1 controls cardiac inflammation and ventricular remodeling during acute myocardial infarction.	23142379
Inflammation, Decreased cardiac function	Altered Intercellular Communication	Compared with their wild-type counterpart, Gal-1-deficient (Lgals1(-/-)) mice showed enhanced cardiac inflammation, characterized by increased numbers of macrophages, natural killer cells, and total T cells, but reduced frequency of regulatory T cells, leading to impaired cardiac function at baseline and impaired ventricular remodeling 7 days after nonreperfused AMI.	23142379
Inflammation	Altered Intercellular Communication	Taken together, our results indicate a protective role for Gal-1 in normal cardiac homeostasis and postinfarction remodeling by preventing cardiac inflammation.	23142379
Inflammation, Primary Biliary Cholangitis, Intrahepatic bile duct, Liver Failure, Immune-mediated	Altered Intercellular Communication	Primary biliary cirrhosis (PBC) is characterized by portal inflammation and immune-mediated destruction of intrahepatic bile ducts that often result in liver failure.	23142582
Inflammation	Altered Intercellular Communication	Tenascin-C levels in synovial fluid are elevated after injury to the human and canine joint and correlate with markers of inflammation and matrix degradation.	23142724
Inflammation, Arthropathy	Altered Intercellular Communication	The objective of the present study was to follow TN-C release into knee synovial fluid after acute joint injury or in joint disease, and to correlate TN-C levels with markers of cartilage matrix degradation and inflammation.	23142724
Inflammation, Anguilla island, Traumatic injury, Knee joint	Altered Intercellular Communication	We find highly elevated levels of TN-C in human knee joints after injury, AIA or OA that correlated with markers of cartilage degradation and inflammation.	23142724
Upgaze palsy, Parinaud Syndrome, Inflammation, Ischemia, Nystagmus, Compression	Altered Intercellular Communication	: Dorsal midbrain syndrome, which is characterized by upgaze paralysis, light-near dissociated pupils, eyelid retraction, and convergence retraction nystagmus, can be caused by compression, ischemia, inflammation, or injury to the dorsal midbrain.	23142879
Inflammation, Facial edema	Altered Intercellular Communication	Inflammation may cause facial nerve edema, and mechanical compression and ischemic change of the facial nerve may occur in the facial nerve canal.	23143560
Virus Diseases, Pneumonitis	Altered Intercellular Communication	CXCL10 may not be a bystander to the severe virus infection but may directly contribute to the pathogenesis of neutrophil-mediated, excessive pulmonary inflammation.	23144331
Pneumonitis	Altered Intercellular Communication	CXCL10-CXCR3 acts in an autocrine fashion on the oxidative burst and chemotaxis in the inflamed neutrophils, leading to fulminant pulmonary inflammation.	23144331
Airway structure, Asthma	Altered Intercellular Communication	Investigation of the association between dietary intake, disease severity and airway inflammation in asthma.	23145908
Inflammation, Asthma	Altered Intercellular Communication	Dietary intake is an important modifiable risk factor for asthma and may be related to disease severity and inflammation, through the effects of intake of anti-oxidant-rich foods and pro-inflammatory nutrients.	23145908
Airway structure, Asthma	Altered Intercellular Communication	It was found that asthmatics within the subgroup of severe persistent asthma have a different pattern of dietary intake as compared with healthy controls, which was associated with lower lung function and increased airway inflammation.	23145908
allergic inflammation	Altered Intercellular Communication	IgE is both a marker and mediator of allergic inflammation.	23146381
Inflammation, Pain Distress Question	Altered Intercellular Communication	Adverse events were found in 11.5% of the patients (inflammation and/or local pain), which were less frequent in men (8.9% versus 16.1%) and similar for both vaccines.	23146445
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Subjects presenting lesions of endodontic origin (LEOs) or pulpal inflammation had an increased risk of developing CHD.	23146639
Palate, Swelling, Inflammation	Altered Intercellular Communication	A 43-year-old male patient presented with port wine stain on the right side of the face, the entire hard and soft palates, the alveolar ridge, and buccal mucosa, and had an excessive accumulation of calcified masses in both supragingival and subgingival sites, with swelling and generalized inflammation throughout the gingiva and alveolar mucosa.	23147344
Malignant Neoplasms	Altered Intercellular Communication	The inflammation-based Glasgow Prognostic Score (GPS) is associated with outcome in a variety of cancers.	23147449
Inflammation, hepcidin, Anemia	Altered Intercellular Communication	The complex interaction between iron stores, hepcidin, inflammation and anemia is poorly comprehended.	23147477
Inflammation, Heart failure, Anemia, hepcidin	Altered Intercellular Communication	We tested the hypothesis that, in stable heart failure patients with anemia, hepcidin is associated with iron deficiency status irrespective of inflammation.	23147477
Inflammation, Heart failure, Anemia, hepcidin	Altered Intercellular Communication	In stable heart failure patients with anemia, hepcidin levels may be more importantly regulated by patients' iron stores than by inflammation.	23147477
Amyotrophic Lateral Sclerosis, Inflammation, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	Although the cause of ALS is unknown, oxidative stress, inflammation, and mitochondrial dysfunction have been identified as important components of its pathogenesis.	23147503
Inflammation, FRONTOMETAPHYSEAL DYSPLASIA 1, End Stage Liver Disease, Liver Failure	Altered Intercellular Communication	Conversely, FMD increased in parallel with Child-Pugh/Mayo Clinic Model for End-stage Liver Disease (MELD) score, bilirubin, serum sodium, plasma renin activity, leukocyte count, platelet count, and with lower arterial pressure, suggesting that enhanced FMD is a feature of advanced liver failure and inflammation.	23147518
vascular inflammations	Altered Intercellular Communication	Our study confirms the robust and widely studied role of CRP as an important marker of vascular inflammation.	23147687
Inflammation, melanoma	Altered Intercellular Communication	No active inflammation or melanoma cells were observed.	23148706
ARCN1 gene, Inflammation	Altered Intercellular Communication	An investigation of the resolution of inflammation (catabasis) in COPD.	23148928
Inflammation, Necrosis	Altered Intercellular Communication	The resolution of inflammation (catabasis) is a complex and highly regulated process where tissue resident macrophages play a key role since they phagocytose apoptotic cells (efferocytosis), preventing their secondary necrosis and the spill-over of their pro-inflammatory cytoplasmic content, and release pro-resolution and tissue repair molecules, such as TGFb, VEGF and HGF.	23148928
ARCN1 gene, Inflammation	Altered Intercellular Communication	Because inflammation does not resolve in COPD, we hypothesized that catabasis may be abnormal in these patients.	23148928
Depression, CTCAE	Altered Intercellular Communication	Although many factors may contribute to P3b amplitude differences - most notably depression and poor sleep quality, symptoms that are prevalent in the GW syndrome groups - our findings in context of previous studies on this population are consistent with the contention that dysfunction in cholinergic and dopaminergic neurotransmitter systems, and in white matter and basal ganglia may be contributing to impairments in GW veterans.	23149040
Inflammation, Pain Distress Question, Non-Small Cell Lung Carcinoma, Depressed mood, Fatigue	Altered Intercellular Communication	We applied novel statistical methods to assess whether variants of 37 inflammation genes may serve as biologic markers of risk for severe pain, depressed mood, and fatigue in non-Hispanic white patients with non-small cell lung cancer.	23149083
Inflammation, Pain Distress Question, Carcinoma of lung, Depressed mood, Fatigue	Altered Intercellular Communication	We used a generalized, multivariate, classification tree approach to explore the influence of single-nucleotide polymorphisms in the inflammation genes in pain, depressed mood, and fatigue in lung cancer patients.	23149083
Inflammation, Granulomatous inflammation	Altered Intercellular Communication	No inflammation around nerves was found in 12 specimens, abutting granulomatous inflammation was found in 1 specimen, and enveloping granulomatous inflammation was found in 1 specimen.	23149199
Necrotizing granulomatous inflammation, Leprosy, Granuloma Annulare	Altered Intercellular Communication	Perineural granulomatous inflammation resembling the perineural infiltrate of leprosy appears to be an uncommon characteristic of granuloma annulare.	23149199
Chronic lymphocytic inflammation, Vasculitis, Clippers	Altered Intercellular Communication	Atypical chronic lymphocytic inflammation with pontocerebellar perivascular enhancement responsive to steroids (CLIPPERS), primary angiitis of the CNS mimicking CLIPPERS or overlap syndrome?	23149266
Encephalomyelitis, Pontine structure, Clippers, Chronic lymphocytic inflammation	Altered Intercellular Communication	A novel type of encephalomyelitis was first described as chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) in 2010 and few additional patients were reported since then.	23149266
Inflammation	Altered Intercellular Communication	Influence of red pepper spice and turmeric on inflammation and oxidative stress biomarkers in overweight females: a metabolomics approach.	23150126
Inflammation, Retinitis Pigmentosa	Altered Intercellular Communication	These data indicate that 4-week supplementation with RP or TM at culinary levels does not alter oxidative stress or inflammation in overweight/obese females with systemic inflammation, or cause a significant shift in the global metabolic profile.	23150126
Inflammation, Pathologic Neovascularization, Dental Plaque	Altered Intercellular Communication	Plaque neovascularization is associated with inflammation and plaque progression.	23150534
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Soluble urokinase plasminogen activator receptor is associated with inflammation in the vulnerable human atherosclerotic plaque.	23150653
Inflammation, Dental Plaque	Altered Intercellular Communication	The aim of this study was to determine whether suPAR measured in the plaque is associated with symptomatic plaques and plaque inflammation.	23150653
Inflammation, Kidney Diseases	Altered Intercellular Communication	Inflammation appears to play important roles in development and/or progression of kidney disease in AAs.	23151275
Inflammation, Fatigue	Altered Intercellular Communication	Plasma CRP and IL-6 were prospectively associated with new-onset fatigue, supporting the hypothesis that low-grade inflammation has a role in the development of fatigue.	23151405
vascular inflammations, Huntington Disease, Endothelial dysfunction	Altered Intercellular Communication	Atherogeneis is a chronic progressive syndrome caused by endothelial dysfunction, vascular inflammation, vessel wall remodeling and eventual vascular flow compromise.	23151748
Inflammation	Altered Intercellular Communication	However, information is scant on the association of chronic systemic inflammation with arterial elasticity in young asymptomatic adults.	23151748
Inflammation	Altered Intercellular Communication	These findings support the role of systemic inflammation in early pathological changes in artery wall in atherogenesis.	23151748
Inflammation, Ischemia	Altered Intercellular Communication	Chronic wounds are characterized by prolonged inflammation, bacterial bioburden, and ischemia.	23151766
Pancreatitis	Altered Intercellular Communication	USP18 is a key regulator of the interferon-driven gene network modulating pancreatic beta cell inflammation and apoptosis.	23152055
Pancreatitis	Altered Intercellular Communication	We presently analyzed the role of ubiquitin-specific peptidase 18 (USP18), an interferon-stimulated gene 15-specific protease, on IFN-induced pancreatic beta cell inflammation and apoptosis.	23152055
Inflammation	Altered Intercellular Communication	Our findings indicate that USP18 inhibition induces inflammation by increasing the STAT signaling and exacerbates IFN-induced beta cell apoptosis by the mitochondrial pathway of cell death.	23152055
Cessation of life, Inflammation	Altered Intercellular Communication	The present study shows that USP18 is a key regulator of IFN signaling in beta cells and underlines the importance of this pathway in beta cell inflammation and death.	23152055
Inflammation, Fever, CTCAE, Kidney Failure	Altered Intercellular Communication	Following treatment with a proton pump inhibitor (PPI) the patient developed fever, signs of inflammation and oliguric renal failure.	23152072
Proteinuria, Fibrosis Assessment, Interstitial inflammation, Kidney Diseases	Altered Intercellular Communication	In adriamycin-induced nephropathic mice, sEH inhibitor did not ameliorate proteinuria or level of serum albumin but reduced the long-term elevated serum creatinine level, interstitial inflammation, fibrosis, and a-SMA expression.	23152298
Chronic liver disease, Inflammation, Liver diseases	Altered Intercellular Communication	miRNAs implicated in chronic liver disease and inflammation showed expression profiles that differed from those in NL and varied among the types and grades of liver diseases.	23152743
Fibrosis, Liver, Carcinogenic Chlorinated Hydrocarbon, Hepatitis	Altered Intercellular Communication	Additionally, we could link miRNA expression pattern with liver fibrosis stage and grade of liver inflammation in CHC.	23152743
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	Modest elevation in BNP in asymptomatic hypertensive patients reflects sub-clinical cardiac remodeling, inflammation and extracellular matrix changes.	23152884
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	Our data provide insight into the mechanisms behind the observed negative prognostic impact of modest elevations in BNP and suggest that in an asymptomatic hypertensive cohort a peripheral BNP measurement may be a useful marker of an early, sub-clinical pathological process characterized by cardiac remodeling, inflammation and ECM alterations.	23152884
Necrotizing granulomatous inflammation, Granulomatous prostatitis	Altered Intercellular Communication	Granulomatous prostatitis, characterized by chronic granulomatous inflammation in the prostate, is rare.	23154024
Granulomatous inflammation, prostatitis	Altered Intercellular Communication	Xanthogranulomatous prostatitis is an even rarer granulomatous inflammation.	23154024
Inflammation	Altered Intercellular Communication	Echocardiogram showed no inflammation vegetation or abnormality of mechanical valve function.	23154479
Pneumonitis	Altered Intercellular Communication	On the contrary, combined administration of RT and trastuzumab is likely to induce or provoke pulmonary inflammation.	23155270
Inflammation, Osage language	Altered Intercellular Communication	The identified SNPs all lie in genes associated with inflammation suggesting inflammation may play a role in OSA pathogenesis.	23155414
Inflammation, Asthma	Altered Intercellular Communication	Salt chamber treatment is ineffective in treating eosinophilic inflammation in asthma.	23157172
Minimal Disseminated Disease, Data types - Address	Altered Intercellular Communication	Further studies on the neurotransmitter systems affected by the genetic polymorphisms found to be associated with MDD in AD may help to elucidate the underlying pathomechanisms of MDD.	23157339
Inflammation, Nasal Polyps, Chronic sinusitis, IL13 gene	Altered Intercellular Communication	Chronic rhinosinusitis with nasal polyps (NP) and allergic rhinitis (AR) is characterized by local Th2 inflammation and up-regulation of IgE; however, IgE in NP is 'polyclonal' and allergen specific, whereas IgE in AR is 'oligoclonal' and allergen specific.	23157682
Inflammation, Nasal Polyps	Altered Intercellular Communication	RAG1 and RAG2 mRNA concentrations are increased in NP and correlated with the magnitude of inflammation and the presence of S. aureus enterotoxin (superantigen)-specific IgE in the nasal polyp mucosa.	23157682
Inflammation, Rupture	Altered Intercellular Communication	C-reactive protein induces expression of matrix metalloproteinase-9: a possible link between inflammation and plaque rupture.	23157807
Inflammation, Pain Distress Question	Altered Intercellular Communication	We asked if cytokine markers of inflammation in preoperative serum or knee synovial fluid (SF) would predict pain 2 years following TKA.	23157967
Inflammation, vinyltriethoxysilane	Altered Intercellular Communication	Thus far, a causal relationship between inflammation and VTE remains to be clarified and more prospective data are required.	23158132
Inflammatory disease of mucous membrane, Irritable Bowel Syndrome	Altered Intercellular Communication	[Relationship between intestinal mucosal inflammation and mental disorders in patients with irritable bowel syndrome].	23158482
Inflammation, Mental disorders, Irritable Bowel Syndrome, Ichthyosis Bullosa of Siemens, Comorbidity, Inflammatory disease of mucous membrane	Altered Intercellular Communication	To examine the relationship between inflammation and the comorbidity of mental disorders with irritable bowel syndrome (IBS) by comparing intestinal mucosa inflammatory biomarkers in patients with and without mental disorders.	23158482
Ichthyosis Bullosa of Siemens, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Mental disorders in the IBS patients may be associated with intestinal mucosal inflammation.	23158482
Inflammation, Superior limbic keratoconjunctivitis	Altered Intercellular Communication	Superior limbic keratoconjunctivitis (SLK) is an uncommon, painful inflammation of the ocular surface localized to the superior sectors of the cornea, limbus, and conjunctiva.	23158547
Inflammation, Ischemic stroke	Altered Intercellular Communication	Association of dimethylarginines and mediators of inflammation after acute ischemic stroke.	23158556
Presenile dementia, Behavioral syndrome associated with physiological disturbance and physical factors	Altered Intercellular Communication	Several neurotransmitter systems can be linked to one specific behavioral syndrome depending on the dementia subtype.	23159046
Inflammation, Atherosclerosis	Altered Intercellular Communication	Research has indicated that inflammation promote all phases of atherosclerosis.	23159230
Inflammation	Altered Intercellular Communication	Soluble urokinase plasminogen activator receptor (suPAR) serum concentrations have recently been described to reflect the severity status of systemic inflammation.	23159293
Inflammation, Hemorrhage	Altered Intercellular Communication	The first was the severe inflammation and the second was the control of hemorrhage from GDA.	23159354
Inflammation	Altered Intercellular Communication	IOFBs may be overlooked because a small penetrating wound may be accompanied by no signs of inflammation for many decades as in this patient's clinical course.	23159363
Inflammatory abnormality of the eye, Lung Neoplasms	Altered Intercellular Communication	We report a case of ocular inflammation and lung tumors in a patient of 84 years for which the diagnosis was made through immunolabelling with IgG4 in lesions biopsied.	23159548
Pain Distress Question, Inflammation, LAURIN-SANDROW SYNDROME, Radicular pain	Altered Intercellular Communication	Symptomatic LSS patients may also suffer from radicular pain, which is a persistent pain transmitted through neural pathways, and is associated with inflammation of the exiting nerve root.	23159960
Inflammation, Disease, Diabetes Mellitus	Altered Intercellular Communication	These results further link PON1 to diabetes and inflammation and may inform the role of HDL in human disease.	23160181
Inflammation	Altered Intercellular Communication	The serotonergic system may be involved in the chronic inflammation evident in psoriatic skin.	23161175
Inflammation, Psoriasis	Altered Intercellular Communication	Through modulating the levels of SERT, there might be a therapeutic possibility for reducing chronic inflammation in psoriasis.	23161175
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Biomarkers of inflammation are associated with colorectal cancer risk in women but are not suitable as early detection markers.	23161620
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	We here report the findings from a large prospective study with repeat measurements of CRP, as well as serum amyloid A (SAA), an additional biomarker of inflammation, and risk of CRC.	23161620
Fibrosis Assessment	Altered Intercellular Communication	Critical role of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the development of inflammation-driven dermal fibrosis in a mouse model of systemic sclerosis.	23161903
Inflammation, Decreased cardiac function	Altered Intercellular Communication	Sickness behavior in community-dwelling elderly: associations with impaired cardiac function and inflammation.	23162010
Inflammation, Hereditary, Choline Dehydrogenase, Mitochondrial, Endothelium, Dental Plaque	Altered Intercellular Communication	(3) By BioCarta and KEGG pathway analysis, we found the target pathways of the hereditary correlated differential genes of CHD BSS with significance were mainly involved in inflammation, plaque formation, endothelial injury, and so on.	23163136
Inflammation, Hereditary, Choline Dehydrogenase, Mitochondrial, Endothelium, Dental Plaque	Altered Intercellular Communication	The hereditary correlated differential genes of CHD BSS were closely associated with inflammation, plaque formation, and endothelial injury.	23163136
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	AFI could better reflect the inflammation degree of UC.	23163137
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome and lower urinary tract symptoms: the role of inflammation.	23165431
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Chronic inflammation has been proposed as a candidate mechanism at the crossroad between these two clinical entities.Aim of study is to examine the correlation among pre-operatory LUTS/BPH severity, MetS features and inflammatory infiltrates in prostatectomy specimens.	23165431
ETV3 wt Allele, prostatitis	Altered Intercellular Communication	In conclusion, MetS can be regarded as a new determinant of prostate inflammation and BPH progression.	23165431
Inflammation, Gastritis, Atrophic	Altered Intercellular Communication	Vitamin C supplementation in relation to inflammation in individuals with atrophic gastritis: a randomised controlled trial in Japan.	23167953
Uremia, Heart failure	Altered Intercellular Communication	[Observation and multifactor analysis of refractory medium-severe heart failure by micro-inflammation modification in uremic patients].	23168207
Uremia	Altered Intercellular Communication	Xuebijing injection can improve heart function in uremic patients by modifying micro-inflammation, whose accumulated dose and therapeutic effect show positive correlation.	23168207
Dyslipidemias	Altered Intercellular Communication	Elevated levels of intact parathyroid hormone (iPTH) may play an important role in the pathogenesis of the dyslipidemia in hemodialysis (HD) patients, but the underlying mechanisms are not clearly defined.	23168847
Atrophic, Inflammatory disease of mucous membrane	Altered Intercellular Communication	IL-1b-31C, IL-1b-511T variant alleles may accelerate gastric mucosal inflammation and atrophy, not only by themselves, but also through the interaction with co-factors.	23169178
Inflammation, Bone necrosis	Altered Intercellular Communication	These data suggest that patients with higher levels of inflammation are at an increased risk of osteonecrosis.	23169328
Inflammation, Squamous cell carcinoma, Fibrosis Assessment, Experimental Organism Basal Cell Carcinoma	Altered Intercellular Communication	The lesions were sorted into two groups: 22 squamous cell carcinomas and one basal cell carcinoma were assigned to group 1 (Marjolin ulcer), and 10 lesions of chronic ulcer with inflammation and fibrosis were assigned to group 2.	23169733
Burn Specimen Source Codes	Altered Intercellular Communication	PET/CT is useful in differentiating Marjolin ulcer from benign inflammatory conditions of chronic nonhealing ulcer in burn scars.	23169733
Inflammation, Atherosclerosis	Altered Intercellular Communication	The independent positive correlation with PAI-I indicates that oxLDL/b2GPI may serve as an early marker of low-grade inflammation and atherosclerosis initiation.	23171597
Inflammation, Fibrosis Assessment, Calcinosis	Altered Intercellular Communication	Native saphenous veins frequently showed fibrosis, but no calcification or active inflammation.	23171851
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Fibrosis can generally be regarded as an errant wound-healing process in response to chronic inflammation, and several studies have shown that the aging prostate tissue microenvironment is rich with inflammatory cells and proteins.	23173053
Inflammation, Bronchiectasis	Altered Intercellular Communication	[Non-cystic bronchiectasis: pathogenic correlations between the parameters of body composition, systemic inflammation and respiratory function].	23173377
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The results suggest that both MO and CRC have low-grade inflammation as part of their etiology.	23173608
Inflammation, Fibrosis Assessment, Connective Tissue Diseases, Peyronie Disease	Altered Intercellular Communication	Peyronie's disease is an acquired connective tissue disorder of the penile tunica albuginea with fibrosis and inflammation.	23173735
Hyponatremia	Altered Intercellular Communication	Severe hyponatremia caused by syndrome of inappropriate secretion of antidiuretic hormone developed as initial manifestation of human herpesvirus-6-associated acute limbic encephalitis after unrelated bone marrow transplantation.	23173742
Inflammation	Altered Intercellular Communication	Vitamin D deficiency is associated with risk for a first cardiovascular event in the general population, possibly because of inflammation, insulin resistance, and neurohumoral activation.	23174181
Inflammation, Fat-free mass, Bronchiectasis	Altered Intercellular Communication	Fat-free mass depletion and inflammation in patients with bronchiectasis.	23174686
Hyperglycemia, Dyslipidemias, Inflammation, Prediabetes syndrome	Altered Intercellular Communication	Pioglitazone slowed progression of CIMT, independent of improvement in hyperglycemia, insulin resistance, dyslipidemia, and systemic inflammation in prediabetes.	23175674
Inflammatory abnormality of the eye	Altered Intercellular Communication	Three hundred and eighty-eight patients (98.7%) presented as elective cases to the outpatient department while 5 (1.3%) presented as emergencies on account of associated ocular inflammation.	23175879
Hemorrhage, Perforation (observation), Peritonitis, Diverticulitis, Orchitis	Altered Intercellular Communication	It may be asymptomatic or complicated by diverticulitis (diverticular inflammation), bleeding, or perforation with peritonitis.	23175883
Inflammation	Altered Intercellular Communication	Changes in activities of daily living, nutrient intake, and systemic inflammation in elderly adults receiving recuperative care.	23176675
Inflammation, Macular Edema, Cystoid	Altered Intercellular Communication	Abolition of all evidence of active inflammation, visual acuity (VA), presence of cystoid macular edema at 6 months and 1 year, and adverse responses to infliximab.	23177362
Chronic disease	Altered Intercellular Communication	Inflammation markers (IM) have been associated with the development of chronic diseases.	23177481
Inflammation, Tachycardia by ECG Finding	Altered Intercellular Communication	Both elevated inflammatory activity and sustained tachycardia reflect unfavourable cardiovascular risk profiles, and there is evidence to suggest the deleterious effects of inflammation are amplified by increased heart rate.	23178644
Fibrosis Assessment, Hepatic inflammation, Hepatitis B	Altered Intercellular Communication	Influence of age and HBeAg status on the correlation between HBV DNA and hepatic inflammation and fibrosis in chronic hepatitis B patients.	23179154
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Liver pathology was regarded as the evaluation criteria to evaluate the correlation between serum HBV DNA level and the severity of liver inflammation and fibrosis.	23179154
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	Of the 215 patients, 136 were HBeAg-positive and 79 were HBeAg-negative; 134 patients had mild hepatic inflammation and fibrosis and 81 had significant hepatic inflammation and fibrosis in pathological diagnosis.	23179154
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	We found that positive correlation between the severity of hepatic inflammation and fibrosis and serum HBV DNA level was only present in HBeAg-negative patients but not HBeAg-positive patients (P < 0.001).	23179154
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	Patients' age was a key factor influencing the correlation between serum HBV DNA level and the severity of hepatic inflammation and fibrosis.	23179154
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	the cutoff values to predict the severity of hepatic inflammation and fibrosis were 33.5 and 36 years, respectively.	23179154
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	There was positive correlation between serum HBV DNA level and hepatic inflammation and fibrosis in both HBeAg-positive and HBeAg-negative patients' aged >= 35 years, but in patients aged <35 years, positive correlation was only observed in HBeAg-negative patients.	23179154
aggressive cancer, Inflammation, Prostate carcinoma, cell injury	Altered Intercellular Communication	In previous studies, we observed a positive association between Trichomonas vaginalis serostatus and risk of prostate cancer, particularly aggressive cancer, which we hypothesized might be due to T. vaginalis-mediated intraprostatic inflammation and cell damage.	23179660
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Although not statistically significant, TLR4 variation appeared to influence the association between T. vaginalis serostatus and prostate cancer risk consistent with the hypothesis that inflammation plays a role in this association.	23179660
Inflammation, Chronic periaortitis, Dilatation of aorta	Altered Intercellular Communication	The larger aortic diameter in male RPF patients may be due to periaortic inflammation with resulting aortic ectasia and supports the classification of RPF into the spectrum of chronic periaortitis.	23179671
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	These cytokines mediate inflammation and have been previously associated with the inflammatory process in several autoimmune diseases.	23179933
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Increased inflammation is common in patients with chronic kidney disease (CKD) and is associated with increased adverse cardiovascular events (CVE).	23180042
Inflammation	Altered Intercellular Communication	The downregulation of frataxin seems to be linked with uremic status, which is usually associated with chronic inflammation and the acceleration of oxidative stress.	23180044
Inflammation, Carcinogenesis	Altered Intercellular Communication	Interleukin 6 (IL6) encodes a cytokine protein, which functions in inflammation, maintains immune homeostasis and plays important roles in cervical carcinogenesis.	23180271
Hyperexplexia	Altered Intercellular Communication	To make a definite diagnosis of hyperekplexia, it may be useful to screen for genes that are involved in the glycinergic neurotransmission system.	23182654
Inflammation, Hematoma, SDSL gene	Altered Intercellular Communication	Inflammation and the coagulation system may influence the genesis of chronic subdural hematoma (CSDH).	23183075
Inflammation, Communicable Diseases, Cyst, Pseudocyst, Tissue Adhesions	Altered Intercellular Communication	Although the mechanism underlying the formation of abdominal pseudocyst remains to be clarified, several predisposing factors for cyst formation have been reported including changes in absorption of CSF due to inflammation or infection, peritoneal adhesions due to previous abdominal surgery, and increase in the protein content of the CSF.	23183082
Inflammation, Hemorrhage, idarubicin, Angiodysplasia, Crohn Disease	Altered Intercellular Communication	The small bowel diagnostic yield for IDA was 53% (n=35), including angiodysplasia 49% (n=17), nonspecific inflammation 34% (n=12), active bleeding 11% (n=4) and Crohn's disease 6% (n=2).	23183118
Inflammation, Myocardial Ischemia	Altered Intercellular Communication	Inflammation and pro- inflammatory cytokines are related to progression of IHD, but their level is seldom analyzed in association with self reported exercise tolerance.	23183510
Dyspnea, Inflammation, Myocardial Ischemia, Angina Pectoris	Altered Intercellular Communication	We have found associations of pro-inflammatory cytokines and inflammation markers with dyspnea or angina pectoris, but the relationship was not consistent in our patients with stable ischemic heart disease.	23183510
Inflammation, Ductal Carcinoma, Papilloma	Altered Intercellular Communication	Maximum and mean elasticity of invasive ductal carcinoma (IDC) were significantly higher than those of fibroadenoma (p<0.01), whereas the difference was not statistically significant with fibroadenosis, papilloma and inflammation (p>0.01).	23184245
Inflammation, Carcinogenesis	Altered Intercellular Communication	Inflammation is commonly observed in radical prostatectomy specimens, and evidence suggests that inflammation may contribute to prostate carcinogenesis.	23184509
prostatitis	Altered Intercellular Communication	Multiple microorganisms have been implicated in serving as a stimulus for prostatic inflammation.	23184509
Inflammation, Cardiovascular system	Altered Intercellular Communication	In renal patients undergoing hemodialysis, paricalcitol treatment significantly reduces oxidative stress and inflammation, two well known factors leading to cardiovascular damage.	23186077
Inflammation, Granulomatosis, Autoimmune Diseases, Granulomatosis with polyangiitis, Systemic Vasculitis	Altered Intercellular Communication	Granulomatosis with polyangiitis (GPA), also known as Wegener's granulomatosis, is an autoimmune disease characterized by inflammation of blood vessels most often seen in the upper respiratory tract, lungs, kidneys, and skin.	23186961
Intermittent	Altered Intercellular Communication	Mechanical traction induced an intermittent depression of EMG amplitudes as a sign of impaired propagation of axon potentials or synaptic transmission.	23188536
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Inflammation as a systemic process plays a central role in atherosclerotic plaque progression (PP).	23188564
Extrapyramidal Disorders	Altered Intercellular Communication	There is experimental evidence that blink rate is affected in extrapyramidal disorders affecting the balance of these neurotransmitters.	23188863
Inflammation, Colitis	Altered Intercellular Communication	FXR agonists have been shown to ameliorate inflammation in murine colitis models.	23189156
Inflammation, Hematoma	Altered Intercellular Communication	The most common primary complications of surgery were hematoma and inflammation.	23189300
Hematoma	Altered Intercellular Communication	Inflammation was the most common complication associated with ramus grafts, while hematoma occurred most often in cases with chin and tuberosity grafts.	23189300
methyldopa, Inflammation	Altered Intercellular Communication	Chronic oxidative stress, inflammation and accumulation of protein-rich deposits both in the retinal pigment epithelium lysosomes and under the retinal pigment epithelium herald the onset of AMD.	23190104
Inflammation, Fibrosis Assessment, Neoplasms	Altered Intercellular Communication	Tumor detection after inflammation or fibrosis on Mohs levels.	23190366
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In Mohs micrographic surgery (MMS), many surgeons will take an additional level based solely on the presence of inflammation or fibrosis.	23190366
Inflammation, Fibrosis Assessment, Neoplasms	Altered Intercellular Communication	The surgeons reviewed their own slides in cases where tumor was detected after a level was taken for inflammation or fibrosis.	23190366
Inflammation, Fibrosis Assessment, Neoplasms	Altered Intercellular Communication	An additional level was taken for inflammation or fibrosis in 6,233 cases (27.8%), resulting in tumor detection in 121 cases (1.9%).	23190366
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Additional levels were taken for inflammation in 66.6% and fibrosis in 63.0%.	23190366
Inflammation, Neoplasms	Altered Intercellular Communication	Fourteen collision tumors were identified and were preceded by inflammation in 71% of cases.	23190366
Inflammation, Neoplasms	Altered Intercellular Communication	The presence of dense inflammation may signal an adjacent collision tumor.	23190366
Inflammation, Fibrosis Assessment, Neoplasms	Altered Intercellular Communication	Taking an additional Mohs level when dense inflammation or fibrosis is present may be warranted to ensure complete tumor removal.	23190366
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Also, elevated oxidative stress and inflammation are the main contributors of endothelial dysfunction.	23190521
Refractory anemias, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The role of inflammation, the autonomic nervous system and classical cardiovascular disease risk factors on subendocardial viability ratio in patients with RA: a cross-sectional and longitudinal study.	23190682
Refractory anemias, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	The objective of the present study was to examine specific predictors of SEVR in RA patients, with a specific focus on inflammation and classical cardiovascular disease (CVD) risk factors.	23190682
Metabolic Diseases	Altered Intercellular Communication	As a potent antioxidant and anti-inflammation agent, kallistatin may also hold therapeutic promise in cardiometabolic disorders.	23190873
Refractory anemias, Inflammation, Rheumatoid Arthritis, Rheumatism	Altered Intercellular Communication	A decrease in high-density lipoprotein (HDL) cholesterol during inflammation is common in many rheumatologic diseases, including rheumatoid arthritis (RA).	23190940
Inflammation, Hemoglobin SS disease with crisis, Erythema Infectiosum, Infected	Altered Intercellular Communication	Given the recent reports of parvovirus B19 infection in Nigeria and the role of inflammation in sickle cell crisis, knowledge of the relationship between the two may be essential for deploying appropriate interventions in infected patients.	23192499
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Epidemiological and experimental evidence indicates chronic inflammation as a risk factor for colorectal cancer.	23192617
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Further adjustment for markers of inflammation (c-reactive protein), endothelial dysfunction (von Willebrand factor), fibrinolytic activity (d-dimer), and g-glutamyl transferase attenuated the increased risk, but risk remained significantly increased (adjusted hazard ratios, 1.73; confidence interval, 1.06-2.83]).	23192755
Inflammation, Damage, Rheumatoid Arthritis, Disease	Altered Intercellular Communication	Positive synovial vascularity in patients with low disease activity indicates smouldering inflammation leading to joint damage in rheumatoid arthritis: time-integrated joint inflammation estimated by synovial vascularity in each finger joint.	23192908
Inflammation, Damage, Disease	Altered Intercellular Communication	Smouldering inflammation reflected by positive synovial vascularity under low disease activity was linked to joint damage.	23192908
Unknown (origin) (qualifier value), Traumatic injury, Neuropathy	Altered Intercellular Communication	trauma, compressive events, inflammations, neuropathies, or it can be idiopathic.	23193847
Gastrointestinal inflammation, Spondylitis	Altered Intercellular Communication	Markers of intestinal inflammation in patients with ankylosing spondylitis: a pilot study.	23194008
Inflammation	Altered Intercellular Communication	Further studies are needed to determine whether fCAL can be used to identify and characterize a subgroup of AS patients whose disease might be driven by subclinical bowel inflammation.	23194008
Rheumatoid Arthritis, Inflammation, Autoimmune Disorder, CTCAE, Synovitis	Altered Intercellular Communication	Rheumatoid arthritis is an autoimmune disorder characterized by persistent synovitis and systemic inflammation.	23194101
Inflammation, fibrogenesis	Altered Intercellular Communication	Galectin-3 is a new biomarker involved in inflammation and fibrogenesis and could therefore contribute to myocardial remodeling.	23194488
Inflammation, Traumatic injury	Altered Intercellular Communication	Advantages include a more precise capsulotomy and more sufficient lensectomy and anterior vitrectomy, stable intraoperative IOP, and reduced surgical trauma and inflammation.	23195254
Inflammation, Necrosis	Altered Intercellular Communication	Fibrinoid necrosis and intramural inflammation were observed in eight cases.	23195911
Inflammation, Rosacea, Edema	Altered Intercellular Communication	Phyma is the last stage of rosacea and is due to chronic inflammation and edema.	23197212
Inflammation	Altered Intercellular Communication	Prediction of early HBeAg seroconversion by decreased titers of HBeAg in the serum combined with increased grades of lobular inflammation in the liver.	23197230
Inflammation	Altered Intercellular Communication	HBeAg levels < 100 PEIU/ml combined with grades of lobular inflammation >=2 are useful for predicting early HBeAg seroconversion.	23197230
Inflammation	Altered Intercellular Communication	In patients without liver biopsies, high ALT levels (>=200 IU/L) can substitute for lobular inflammation (grades >=2).	23197230
Inflammation, Liver carcinoma, Lymphoproliferative Disorder of the Skin, Malignant Neoplasms, FAM126A gene, Cessation of life, Chronic liver disease	Altered Intercellular Communication	Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to reduce chronic inflammation and risk of many cancers, but their effect on risk of hepatocellular carcinoma (HCC) and death due to chronic liver disease (CLD) has not been investigated.	23197492
aggressive cancer, Liver carcinoma, Hepatitis, FAM126A gene	Altered Intercellular Communication	Hepatocellular carcinoma (HCC) is a highly aggressive cancer that is linked to chronically dysregulated liver inflammation.	23197495
Conscious, Inflammation	Altered Intercellular Communication	The findings add some support to accumulating evidence for low conscientiousness being linked to higher levels of inflammation and poorer general health.	23197841
Airway structure, Gastroenteritis	Altered Intercellular Communication	Upper airway inflammation was seen in 68%, lower airway inflammation in 20% and gastroenteritis in 6%.	23198577
Airway structure	Altered Intercellular Communication	Lower airway inflammation decreased from 20% in 2009-2010 to 7% in 2010-2011.	23198577
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Testing the hypothesis of a relationship between aspirin resistance and vascular function, inflammation and coagulation, we recruited 175 stable CAD outpatients taking 75 mg aspirin daily.	23198725
skin damage, Inflammation	Altered Intercellular Communication	In BP, there is an interplay between inflammation and coagulation both locally, which contributes to skin damage, and systemically, which leads to a prothrombotic state.	23199326
Hemorrhagic, Waldenstrom Macroglobulinemia, Neoplasm Metastasis	Altered Intercellular Communication	Histologically, primary and metastasis comprised nodules of bland ovoid cells, with primary additionally showing hemorrhagic cavities, fibrous capsule, and lymphoplasmacytic inflammation.	23199525
Airway structure, Wheezing	Altered Intercellular Communication	Assessment of airflow limitation, airway inflammation, and symptoms during virus-induced wheezing episodes in 4- to 6-year-old children.	23199600
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	We sought to prospectively assess airflow limitation and airway inflammation in children 4 to 6 years old with episodic virus-induced wheeze.	23199600
Airway structure, Chronic Obstructive Airway Disease, Wheezing	Altered Intercellular Communication	Mild episodes of wheeze in preschoolers are characterized by enhanced airway inflammation, reversible airflow limitation, and asthma-related symptoms.	23199600
Inflammation, Asthma	Altered Intercellular Communication	Longitudinal follow-up suggests that symptoms, inflammation, and lung function correlate well in this phenotype of asthma.	23199600
ARCN1 gene, Inflammation	Altered Intercellular Communication	The increased oxidative stress in patients with COPD is the result of exogenous oxidants namely pollutants and cigarette smoke as well as endogenous oxidant production during inflammation.	23199890
Inflammation, Fever, CTCAE	Altered Intercellular Communication	After the EBUS-TBNA, all cases showed prolonged fever and systemic inflammation despite receiving a sufficient dose of broad-spectrum antibiotics.	23199981
Toxic nephropathy, Hemorrhage, Ulceration, CTCAE, Duodenal inflammation	Altered Intercellular Communication	Twenty patients had treatment-related duodenal toxicity events, such as duodenal inflammation, ulceration, and bleeding.	23200173
Inflammation	Altered Intercellular Communication	In 291 patients, endomyocardial biopsies from the right ventricle were performed upon first hospital admission for assessment of cardiac inflammation.	23200269
Inflammation, Cachexia	Altered Intercellular Communication	The white adipose tissue responds to cachexia with marked local inflammation and may be thus a relevant contributor to systemic inflammation.	23200412
Inflammation, Metabolic Problems	Altered Intercellular Communication	: inflammation, weathering, and metabolic problems in late life.	23201190
Inflammation, "Alzheimers Disease", Data types - Address, Nerve Degeneration	Altered Intercellular Communication	Inflammation has been proposed as a leading force in neurodegeneration and Interleukin (IL)-18 is a pro-inflammatory cytokine which is suggested to be implicated in Alzheimer's disease (AD).	23201485
Inflammation, Hyperautofluorescent retinal lesion	Altered Intercellular Communication	Direct sun-gazing may damage the retinal structures resulting in macular inflammation and increased focal metabolism, which explains the hyperautofluorescence.	23202400
Inflammation	Altered Intercellular Communication	In summary, RIPC regulates HIF-1a levels, apoptosis and inflammation in the myocardium of cardiosurgical patients and leads to increased concentrations of circulating cytokines.	23203207
Conjunctivitis	Altered Intercellular Communication	Seven days after the operation, the fibrin glue group showed milder conjunctival inflammation than the suture group (p = 0.000).	23204794
Inflammation, Swelling	Altered Intercellular Communication	There was no evidence of inflammation or swelling within the opening.	23204803
Inflammation, Postoperative infection	Altered Intercellular Communication	Normal range of the inflammation related laboratory findings and predictors of the postoperative infection in spinal posterior fusion surgery.	23205236
Gastritis, Fibrosis Assessment, Duodenal Ulcer, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Cystic fibrosis, gastroduodenal inflammation, duodenal ulcer, and H. pylori infection: the "cystic fibrosis paradox" revisited.	23206871
Inflammation, Gastric metaplasia	Altered Intercellular Communication	On duodenal histology, 94.5%, showed active inflammation and 66.7% gastric metaplasia.	23206871
Herpes Zoster Ophthalmicus	Altered Intercellular Communication	Incidence of herpes zoster ophthalmicus: results from the Pacific Ocular Inflammation Study.	23207173
Airway structure	Altered Intercellular Communication	Chronic airway inflammation is one of the proposed mechanisms to explain the formation of TO nodules.	23207265
Bronchial brand of guaifenesin-theophylline, Inflammation	Altered Intercellular Communication	The foreign body could not be identified under conventional bronchoscopy because of the presence of multiple bronchial stenoses due to chronic inflammation.	23207364
Granulomatous inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Granulomatous inflammation detected by endobronchial ultrasound-guided transbronchial needle aspiration in patients with a concurrent diagnosis of cancer: a clinical conundrum.	23207457
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation is occasionally identified in this setting and has unclear clinical implications.	23207457
Granulomatous inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Therefore, we set out to describe a cohort of patients found to have evidence of granulomatous inflammation during EBUS-TBNA done for diagnosis and/or staging of concurrent cancer.	23207457
Communicable Diseases, Sarcoidosis, Primary malignant neoplasm, Granulomatous inflammation	Altered Intercellular Communication	Patients with evidence of granulomatous inflammation during EBUS-TBNA that was not attributable to an infectious etiology or prior sarcoidosis and a concurrent diagnosis of cancer were included.	23207457
Granulomatous inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Granulomatous inflammation was identified in 154/1275 patients (12.1%), of whom 12/154 (7.8%) had a concurrent diagnosis of cancer.	23207457
Granulomatous inflammation, Malignant Neoplasms	Altered Intercellular Communication	Granulomatous inflammation is occasionally identified in mediastinal and/or hilar lymphadenopathy in patients with concurrent malignancy.	23207457
Granulomatous inflammation, Malignant Neoplasms	Altered Intercellular Communication	Although the clinical implications of this phenomenon remain to be clarified, these findings emphasize the importance of histologic confirmation of suspected lymph node involvement and suggest that the presence of granulomatous inflammation on EBUS-TBNA may occasionally be consistent with active malignancy and prompt further investigations.	23207457
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) has been linked to a state of cerebral and systemic inflammation.	23207486
Bronchial brand of guaifenesin-theophylline, Bronchiectasis, Airway structure	Altered Intercellular Communication	Bronchiectasis is classically defined as irreversible bronchial dilatation that represents the sequelae of chronic airway inflammation and is permanent, reflecting the presence of bronchiectasis.	23207538
Inflammation, Bulla, Erythema, Mixed Connective Tissue Disease, Toxic Epidermal Necrolysis, Adenocarcinoma of lung (disorder)	Altered Intercellular Communication	We present the case of a 58-year-old woman with history of Sharp's syndrome and adenocarcinoma of the lung, who developed toxic epidermal necrolysis after the first cycle of pemetrexed, including erythema, bullae, extensive skin denudation, subsequent systemic inflammation and severe deterioration in general condition.	23207626
Renal Insufficiency, Inflammation, Malnutrition, Anemia	Altered Intercellular Communication	The most common potential causes of anemia were inflammation, severe renal impairment, severe malnutrition, and iron deficiency; each of these causes was found in at least one-third of patients with anemia.	23207807
Inflammation, Obesity	Altered Intercellular Communication	The increased S100A9 reported for obesity and insulin resistance may be envisioned as a compensatory mechanism for inflammation.	23207880
Inflammation, Scleritis	Altered Intercellular Communication	Surgically induced necrotising scleritis (SINS) presents as a focal area of intense scleral inflammation next to the site of previous scleral or limbal excision.	23208487
Ischemia, Sensorineural Hearing Loss (disorder), Inflammation	Altered Intercellular Communication	In conclusion, HDVC may enhance hearing recovery in ISSNHL patients, which suggests that HDVC reduces levels of reactive oxygen metabolites produced by inner ear ischemia or inflammation, and that HDVC could be considered for the treatment of ISSNHL.	23208525
Inflammation, Ulcer	Altered Intercellular Communication	The ulcers heal due to the fact that the transplanted cells stimulate local regeneration processes, angiogenesis, ceased inflammation and apoptosis.	23210179
Inflammation	Altered Intercellular Communication	Reconstructive conjunctivo-sclerokeratoplasty resulted in arrest of inflammation and visual function recovery in 3 patients.	23210346
Inflammation, Anemia, Chronic disease	Altered Intercellular Communication	Once anemia is diagnosed, treatment should be based on etiology (most commonly, iron deficiency followed, in order of prevalence, by inflammation or chronic disease).	23210492
Inflammation, Periodontitis, Endothelial dysfunction	Altered Intercellular Communication	Chronic periodontitis (CP) is characterized with inflammation of the gingival tissues, which causes endothelial dysfunction in different organs.	23211042
Inflammation	Altered Intercellular Communication	Leptin plays not only an important role in regulation of food intake, but also in the mechanism of inflammation.	23211301
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Dysentery	Altered Intercellular Communication	We conclude that 1) the increased leptin in exacerbated UC is related to the increased serum proinflammatory cytokines IL-1b, TNF-a and IL-6 levels; 2) In patients with infectious diarrhea, the concentrations of leptin in intestinal mucosa correlates with serum concentrations of cytokines IL-1b, IL-6 and TNF-a and with an increased expression of leptin mRNA in intestinal mucosa but not with alterations in serum levels of this hormone; 3) leptin may serve as useful predictive marker of inflammation in inflammatory bowel disease (IBD).	23211301
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Dysentery	Altered Intercellular Communication	We conclude that 1) the increased leptin in exacerbated UC is related to the increased serum proinflammatory cytokines IL-1b, TNF-a and IL-6 levels; 2) In patients with infectious diarrhea, the concentrations of leptin in intestinal mucosa correlates with serum concentrations of cytokines IL-1b, IL-6 and TNF-a and with an increased expression of leptin mRNA in intestinal mucosa but not with alterations in serum levels of this hormone; 3) leptin may serve as useful predictive marker of inflammation in inflammatory bowel disease (IBD).	23211301
Inflammation, Metabolic Diseases	Altered Intercellular Communication	Recent findings have implicated the gut microbiota as a contributor of metabolic diseases through the modulation of host metabolism and inflammation.	23212374
Inflammation, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is associated with lipid accumulation and inflammation in the arterial wall, and bacteria have been suggested as a causative agent of this disease.	23212374
Inflammation, Schizophrenia	Altered Intercellular Communication	There is a growing body of evidence confirming the involvement of oxidative stress and inflammation in pathogenesis of schizophrenia.	23212700
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Inflammation and oxidative stress play a crucial role in the development of colorectal cancer (CRC) and interference with these mechanisms represents a strategy in CRC chemoprevention.	23213070
Dermatitis	Altered Intercellular Communication	Water influences skin inflammation of the external auditory canal.	23213950
Dermatitis	Altered Intercellular Communication	Water sport players had a higher risk for ear skin inflammation than football players.	23213950
Inflammation	Altered Intercellular Communication	Nasal inverted papilloma complicated with polyps may result from long-term inflammation that occurred in the surface of the epithelia of superficial papilloma.	23214313
Hepatitis B, Acute-On-Chronic Liver Failure, CRNKL1 wt Allele	Altered Intercellular Communication	Although regulatory T cells (Treg) and interleukin-17-producing CD4 T cells (Th17) have been demonstrated to play opposing roles in inflammation-associated diseases, their frequency and balance in different stages of hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACLF) remain unknown.	23215950
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The most common histopathologic finding was nonspecific inflammation with associated fibrosis.	23217503
Inflammation, Fibrosis Assessment, Lacrimal Duct Obstruction	Altered Intercellular Communication	Use of the lacrimal trephine to open canalicular obstructions provided tissue samples that revealed nonspecific inflammation and fibrosis as a common underlying histopathology.	23217503
deficiency aspects, Inflammation, Anemia	Altered Intercellular Communication	Multiple criteria models were used to determine the prevalence of Fe deficiency, anaemia and inflammation.	23218134
Inflammation, Kidney Failure, ETV3 wt Allele, Diabetes Mellitus	Altered Intercellular Communication	Multivariate analysis showed that old age, multi-vessel involvement, high levels of inflammation, diabetes and MetS were associated with 1-year composite MACE in patients with renal insufficiency.	23218489
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation was observed in 11 patients (61%) and was severe in 1.	23218689
Inflammation, Edema	Altered Intercellular Communication	Despite inflammation in several patients, there was prolonged edema reduction and improvement in vision in several patients.	23218689
Pain Distress Question, Acute inflammation	Altered Intercellular Communication	Loteprednol etabonate gel 0.5% was efficacious and safe in treating postoperative inflammation and pain.	23218817
Communicable Diseases, Inflammation	Altered Intercellular Communication	This result supports recent findings that inflammation and infection might play an important role in the pathogenesis of ARONJ.	23218978
Inflammation, hepcidin, Anemia, Crohn Disease	Altered Intercellular Communication	Hepcidin is a key mediator of anemia of inflammation in Crohn's disease.	23219355
Inflammation, Colonization	Altered Intercellular Communication	There is evidence that chronic inflammation due to bacterial wound colonization delays wound healing.	23220150
Inflammation, Clostridium difficile infection	Altered Intercellular Communication	Besides demonstrating the increasing incidence and severity of Clostridium difficile infection, prognostic factors such as co-morbidities and laboratory parameters of inflammation were also identified.	23220365
Polymyositis, Idiopathic Inflammatory Myopathies, Myositis	Altered Intercellular Communication	Polymyositis (PM) is an idiopathic inflammatory myopathy manifested by proximal limb muscles weakness, elevated creatinin kinase, electromyography changes, and muscle inflammation in biopsy.	23220804
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	The inflammation of IBD exposes plectin, stimulating a secondary immune response that may, in susceptible individuals, crossreact with the skin, provoking BP.	23221017
Cessation of life, Throat irritation, Inflammation	Altered Intercellular Communication	Chlorine is a respiratory irritant and can produce symptoms ranging from mild eye, nose, and throat irritation to severe inflammation of the lung, which can lead to death.	23222372
Sepsis, Inflammation	Altered Intercellular Communication	Obese patients had higher median C-reactive protein levels and a higher frequency of sepsis using the systemic inflammatory response syndrome criteria (72.4% versus 64.1%; p=0.03), than nonobese patients, suggesting greater systemic inflammation.	23222873
Inflammation	Altered Intercellular Communication	Contrast enhanced ultrasound (CEUS), based on the theory of inflammation and neoangiogenesis, seems to have a great potential for the detection of unstable plaques.	23222935
Inflammation, Hematoma	Altered Intercellular Communication	Nevertheless, the results of the morphological analysis demonstrate the early beginning of reparative process around the hematoma, securing the possibility of the septic inflammation.	23222978
Inflammation	Altered Intercellular Communication	The experience was successful in all cases but one, where the septic inflammation of the subcutaneous pocket developed.	23222983
Amyloidosis	Altered Intercellular Communication	Serum amyloid A (SAA) is best known for being the main component of amyloid in the inflammation-related disease amyloid A (AA) amyloidosis.	23223242
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Here we describe the role of myeloid-related protein Mrp14, a recently described amplifier of inflammation, in Alzheimer's disease and in the related amyloid precursor protein/presenilin1 (APP/PS1) mouse model.	23223301
Inflammation	Altered Intercellular Communication	Cardiometabolic profile and markers of inflammation are more severely altered in men and women with both IFG and IGT compared with those with IFG alone.	23223343
Inflammation, Anemia	Altered Intercellular Communication	Anemia and serum markers of inflammation were present in all cases.	23223599
Malignant neoplasm of urinary bladder, Inflammation, Neoplasms	Altered Intercellular Communication	Data from bladder cancer human biopsies revealed that B1 receptor expression was increased in all tumor samples and under conditions of chronic inflammation.	23224295
Granulomatous inflammation	Altered Intercellular Communication	Brimonidine-timolol fixed combination induced granulomatous inflammation of the eye.	23224363
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation resolved with the cessation of antiglaucomatous drugs and topical corticosteroid treatment.	23224363
Iritis, Conjunctivitis, Hyperemia	Altered Intercellular Communication	Hyperemia may be associated with other signs such as iritis and keratic precipitates or conjunctival inflammation.	23224363
Granulomatous inflammation	Altered Intercellular Communication	In such cases, granulomatous inflammation may be considered in the differential diagnosis.	23224363
Inflammation, Squamous cell carcinoma of esophagus	Altered Intercellular Communication	The authors isolated exosomes in serum samples from patients who had ESCC and from patients who had benign diseases without systemic inflammation.	23224754
Inflammation, Squamous cell carcinoma of esophagus	Altered Intercellular Communication	The expression levels of exosomal miR-21 were significantly higher in patients with ESCC than those with benign diseases with and without (C-reactive protein <0.3 mg/dL) systemic inflammation.	23224754
Inflammation, Squamous cell carcinoma of esophagus	Altered Intercellular Communication	The current results confirmed that exosomal miR-21 expression is up-regulated in serum from patients with ESCC versus serum from patients who have benign diseases without systemic inflammation.	23224754
Intraocular inflammation, Leukemia, Myelocytic, Acute	Altered Intercellular Communication	Timely anterior chamber aspiration and subsequent cytology is useful in differentiating leukemic hypopyon from true intraocular inflammation in AML patients.	23225088
Inflammation, Heart failure, Cardiovascular system	Altered Intercellular Communication	Acute cardiovascular toxicity of sterilizers, PHMG, and PGH: severe inflammation in human cells and heart failure in zebrafish.	23225114
Cessation of life, Acute inflammation	Altered Intercellular Communication	Zebrafish embryos, which were exposed to the sterilizer, showed early death with acute inflammation and attenuated developmental speed.	23225114
Atherogenesis, Inflammation	Altered Intercellular Communication	In conclusion, the sterilizers showed acute toxic effect in blood circulation system, causing by severe inflammation, atherogenesis, and aging, with embryo toxicity.	23225114
Inflammation, Aortic valve disorder	Altered Intercellular Communication	Inflammation is associated with the remodeling of calcific aortic valve disease.	23225202
Inflammation, Heart failure	Altered Intercellular Communication	Different monocytic subsets are important in inflammation and tissue remodelling, but although heart failure (HF) is associated with local and systemic inflammation, their roles in HF are yet unknown.	23226928
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Haemophilus influenzae is the most common colonizing bacteria of the bronchial tree in chronic obstructive pulmonary disease (COPD), and positive cultures for this potentially pathogenic microorganism (PPM) has been associated with local inflammation changes that may influence the relationships between H. influenzae and the bronchial mucosa.	23228114
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	The role of oxidative stress and inflammation in the early evaluation of acute non-ST-elevation myocardial infarction: an observational study.	23228975
Inflammation, Electrocardiogram: myocardial infarction (finding), Angina Pectoris	Altered Intercellular Communication	We aimed to assess the role of oxidative stress (OS) and inflammation in the early evaluation of initial acute non -ST -elevation myocardial infarction (NSTEMI) compared with unstable angina pectoris (USAP).	23228975
Inflammation, Necrotizing vasculitis, Eosinophilic disorder, Eosinophilic granulomatosis with polyangiitis, Asthma	Altered Intercellular Communication	Churg-Strauss syndrome is defined as an eosinophil-rich, granulomatous inflammation involving the respiratory tract, along with necrotizing vasculitis affecting small- to medium-sized vessels, and is associated with asthma and eosinophilia.	23229164
Skin necrosis, Inflammation	Altered Intercellular Communication	One patient developed skin necrosis at the edge of the incision in the dorsum of the foot and another whose sinus located in the toe suffered inflammation and exudation.	23230757
Acute Lung Injury, Inflammation	Altered Intercellular Communication	Recently, a new mediator of inflammation, HMGB1 protein has been identified that contributes to acute lung injury.	23231044
Renal Insufficiency, Inflammation	Altered Intercellular Communication	Inflammation appears to be associated with mineral stress even in the absence of renal dysfunction.	23231493
Oxyphilic Adenoma	Altered Intercellular Communication	Periductal inflammation/fibrosis was common in sialolipoma and oncocytic lipoadenoma.	23232852
Inflammation	Altered Intercellular Communication	Traffic pollution was related to increased inflammation for 3-, 7-, 14- and 30-day exposure periods.	23232970
Inflammation	Altered Intercellular Communication	The purpose of this investigation was to determine if the long pentraxin 3 (PTX-3) may be a useful marker of intradialytic inflammation since it is rapidly released in the vasculature.	23235124
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The association between nutritional status, antioxidant human paraoxonase-1 (PON1) activity and low grade inflammation in hemodialized (HD) patients with chronic kidney disease (CKD) is unclear.	23235285
Inflammation	Altered Intercellular Communication	In intraoperative findings, the tympanic segment of the fallopian canal was found to be eroded because of inflammation.	23235551
Inflammation, Glomerulonephritis	Altered Intercellular Communication	Hence, the sequela is continual glomerular deposition of complement factors with resultant inflammation and development of an 'atypical' postinfectious glomerulonephritis.	23235567
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The observed coronary LGE seems to be rather unspecific, and differentiation between coronary vessel wall fibrosis and inflammation still remains unclear.	23236382
Inflammation	Altered Intercellular Communication	Treatment was generally well tolerated, but moderately severe adverse events (i.e., body and face inflammation), were observed in four Schistosoma egg-negative children.	23236526
Inflammation, Cystadenocarcinoma, Xanthogranulomatous cholecystitis, Ulcer, Adenocarcinoma, Lobular Endocervical Glandular Hyperplasia, Adenoma	Altered Intercellular Communication	The frequency of histological lesions were as follows: acute gangrenous inflammation (8 cases, 1.5%), Rokitansky-Aschoff sinuses (RAS) (351 cases, 65%), microliths or inspissated bile in RAS (108 cases, 20%), adenomyomatous changes (16 cases, 3.0 %), focal abscess formations (12 cases, 2.2%), focal xanthogranulomatous changes (15 cases, 2.8%), mucosal ulcers (61 cases, 11.3%), cholesterosis (62 cases, 11%), cholesterol polyp (32 cases, 6%), pyloric gland metaplasia (292 cases, 54%), adenoma (7 cases, 1.3%), xanthogranulomatous cholecystitis (5 cases, 1%), invasive adenocarcinoma (12 cases, 2.2%), and cystadenocarcinoma (1 cases, 0.2%).	23236547
Inflammation, Mediastinitis	Altered Intercellular Communication	Mediastinitis after coronary artery bypass grafting (CABG) gives a longstanding chronic inflammation and has a detrimental negative effect on long-term survival.	23237029
Inflammation, Mediastinitis, Atherosclerosis	Altered Intercellular Communication	This may confirm the importance of inflammation as a major contributor to the pathogenesis of atherosclerosis and explain the negative effect of mediastinitis on a long-term survival.	23237029
Angina, Unstable	Altered Intercellular Communication	Exaggerated myocardial oxLDL amount and LOX-1 receptor over-expression associated with coronary microvessel inflammation in unstable angina.	23237633
Atherosclerosis	Altered Intercellular Communication	The purposes of this study are to investigate whether coronary microvessels are involved in coronary atherosclerosis and whether increased myocardial oxLDL amount can be associated with coronary microvessel inflammation.	23237633
Inflammation, Mitral Valve Stenosis, Angina Pectoris	Altered Intercellular Communication	A combination of immunohistochemical, RT-PCR and real-time PCR studies performed on myocardial biopsy specimens from patients with mitral stenosis (control hearts, CHs) and from unstable and stable angina patients (UAP and SAP), demonstrated that myocardial oxLDL was associated with a chronic low-grade inflammation in SAP and with a severe high grade inflammation in UAP.	23237633
Heart Diseases, Myocarditis	Altered Intercellular Communication	We report on two cases, where an endocardial and myocardial inflammation may be a relevant component of cardiac disease.	23238003
Myocarditis	Altered Intercellular Communication	Myocardial biopsy and MRI supported endocardial and myocardial inflammation.	23238003
Troponin T, Cardiac Muscle, Myocarditis	Altered Intercellular Communication	Elevated cardiac troponin T persisted in the presence of cyclophosphamide treatment, subsequent MRI suggested myocardial inflammation.	23238003
Myocarditis	Altered Intercellular Communication	We hypothesize that low-grade endocardial and myocardial inflammation may be more relevant in systemic sclerosis than appreciated previously.	23238003
Impaired cognition, Hepatitis, Visual Impairment, Congestive heart failure, Have Dizziness, Anemia, Polypharmacy, Kidney Failure	Altered Intercellular Communication	TEMs were anemia, congestive heart failure, liver inflammation, polypharmacy, renal insufficiency, cognitive impairment, dizziness, frequent mental distress, mobility difficulty, and visual impairment.	23238312
Inflammation, Waldenstrom Macroglobulinemia	Altered Intercellular Communication	The clinicopathologic study revealed intense lymphoplasmacytic and sclerosing inflammation, with IgG4-positive plasma cells and an IgG4:IgG ratio >40%.	23238395
Inflammation, Fibrosis Assessment, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Systemic inflammation, oxidative stress, and atrial fibrosis are identified as the main mechanisms for atrial fibrillation (AF).	23238698
Inflammation	Altered Intercellular Communication	One of the most controversial issues is the role of inflammation.	23238795
Inflammation	Altered Intercellular Communication	It is well known that inflammation involves an increased expression/activity of inflammatory mediators.	23238795
Inflammation, Varicose	Altered Intercellular Communication	The aim of this study was to investigate the presence or absence of mediators of inflammation in varicose as compared to healthy veins.	23238795
Inflammation, Varicose	Altered Intercellular Communication	No difference was observed for enzymes involved in inflammation and responsible for arachidonic acid metabolism such as the acute phase reactant secreted phospholipase A2-IIA and cyclooxygenase-2, as determined in varicose and healthy veins by Western blot and real-time qRT-PCR.	23238795
Inflammation, Varicose	Altered Intercellular Communication	Our experiments demonstrate no increase in the presence of mediators of inflammation in varicose as compared to healthy veins, suggesting that inflammation may not be an important contributor to the pathogenesis of varicose veins.	23238795
Inflammation, Lymphocytic hypopituitarism	Altered Intercellular Communication	Lymphocytic hypophysitis (LYH) is a chronic inflammation that primarily affects the pituitary gland.	23238905
Inflammation, Kit Ligand, human	Altered Intercellular Communication	RDW, markers of inflammation and stem cell factor (SCF) were determined.	23239558
Inflammation, Kit Ligand, human	Altered Intercellular Communication	RDW correlated to markers of inflammation and inversely to SCF.	23239558
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Research into the etiology of breast cancer has recently focused on the role of the immunity and inflammation.	23239971
Inflammation, Heart failure	Altered Intercellular Communication	Monocytes play important roles in inflammation, angiogenesis and tissue repair and may contribute to the pathophysiology of heart failure (HF).	23240665
Inflammation, Periodontitis, Osteopenia	Altered Intercellular Communication	Subjects were classified as follows: 1) healthy subjects with no attachment loss >1mm and no clinical signs of gingival or periodontal inflammation; 2) diseased subjects with mild periodontitis (less than 15%0 of global periodontal bone loss); 3) subjects with moderate periodontitis (less than 4 interproximal sites with bone loss = or >50 percent and mean bone loss between 15 and 30%); 4) subjects with severe periodontitis (more than 7 interproximal sites with >50% bone loss and mean bone loss >35%0).	23241110
Inflammation	Altered Intercellular Communication	A 69-year-old fisherman underwent laparoscopic cholecystectomy due to severe inflammation in the gallbladder.	23241376
Inflammation, Hypoxia-Ischemia, Brain, Hyperoxia	Altered Intercellular Communication	Hyperoxic resuscitation after hypoxia-ischemia induces cerebral inflammation that is attenuated by tempol in a reporter mouse model with very young mice.	23241583
Tissue damage, Inflammation	Altered Intercellular Communication	Mechanisms for tissue damage by hypoxia/ischemia in the extreme premature involve inflammation.	23241583
Inflammation, Brain Injuries	Altered Intercellular Communication	Tempol treatment attenuated inflammation but did not reduce the extent of histological cerebral damage.	23241583
Inflammation	Altered Intercellular Communication	Epigenetic modification, oxidative stress, and inflammation play an important role in the pathogenesis of the disease.	23242124
Inflammation, Impaired cognition, MS gene, Disability, Axon loss	Altered Intercellular Communication	Gray matter lesions are thought to play a key role in the progression of disability and cognitive impairment in multiple sclerosis (MS) patients, but whether gray matter damage is caused by inflammation or secondary to axon loss in the white matter, or both, is not clear.	23242282
Meningitis	Altered Intercellular Communication	In an analysis of postmortem brain samples from 44 cases of secondary progressive MS, 26 cases were characterized by meningeal inflammation with ectopic B-cell follicles and prominent gray matter pathology; subpial cortical lesions containing dense perivascular lymphocytic infiltrates were present in 11 of these cases.	23242282
Inflammation, Damage, White matter lesions	Altered Intercellular Communication	These findings indicate that both meningeal and intraparenchymal inflammation may contribute to cortical damage during MS progression, and that intracortical inflammation may be sustained by an EBV-driven immunopathologic response, similar to findings in white matter lesions and meninges.	23242282
Graves Disease, Chronic inflammation, Endothelial dysfunction	Altered Intercellular Communication	The etiopathogenesis of Graves' disease (GD) has not been clearly elucidated although the role of chronical inflammation and endothelial dysfunction has been established.	23242661
Inflammation, herpesvirus 3, human	Altered Intercellular Communication	Late VZV vasculopathy is distinguished by viral antigen without inflammation in media, revealing a human virus in an immunoprivileged arterial media.	23243076
Inflammation, herpesvirus 3, human	Altered Intercellular Communication	Association of thickened intima and inflammation in vaso vasorum vessels in early VZV vasculopathy support the role of virus-induced inflammation in vessel wall remodeling.	23243076
Inflammation, Pancreatic carcinoma	Altered Intercellular Communication	Although development of pancreatic cancer is associated with states of insulin resistance and chronic inflammation, the mechanistic basis of the associations is poorly understood.	23243202
Refractory anemias, Inflammation	Altered Intercellular Communication	The influence of inflammation on the myocardium in RA needs further studies.	23244227
Inflammation, MS gene	Altered Intercellular Communication	We hypothesized that due to chronic inflammation, MS patients would present with a higher levels of cardiovascular (CV) risk factors than non-MS patients.	23244431
Inflammation, Fibrous	Altered Intercellular Communication	The pathophysiology of this phenomenon remains unclear but could be related to chronic inflammation with development of a fibrous layer along the visceral pleura.	23244504
Inflammation, Malnutrition	Altered Intercellular Communication	Malnutrition and chronic inflammation in dialysis patients negatively impact their survival prognosis, and nutrients, such as omega-3 oils, are postulated to reduce proinflammatory response.	23244537
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	Pentraxin3 (PTX3), a recently discovered inflammatory mediator, is produced abundantly in various cells in atherosclerotic lesions, and therefore, its plasma level could reflect local inflammation at the site of atherosclerotic lesion.	23245734
Dermatitis, Mental disorders, Data types - Address	Altered Intercellular Communication	Strategies to prevent AD or to aggressively treat early skin inflammation might modify the risk of mental health disorders in at-risk children.	23245818
vascular inflammations, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Children's early development of cardiovascular disease (CVD) risk factors may include exposure to key biological components responsible for vascular inflammation in young adults.	23246302
Orbital Pseudotumor	Altered Intercellular Communication	Atypical idiopathic orbital inflammation in a young girl.	23247034
Orbital Pseudotumor	Altered Intercellular Communication	After a negative workup, she was diagnosed and treated for idiopathic orbital inflammation (IOI) with a brisk response to oral steroids.	23247034
Inflammation, Leukocytes	Altered Intercellular Communication	Blood data representing inflammation (WBC and CRP) showed marked differences, especially on postoperative day 7 (P = 0.0016 and P = 0.0061, respectively).	23247737
Cervical Soft Tissue Neoplasm, Inflammation, Necrotizing fasciitis	Altered Intercellular Communication	Necrotizing fasciitis is a potentially life-threatening complication of severe cervical soft tissue inflammation.	23247748
Cystic medial necrosis of aorta, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In contrast, TAV-associated ascending aortas were characterized by a significant severity of elastic fragmentation, cystic medial necrosis, medial fibrosis and inflammation.	23248206
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	They, combined with hypertension and age, significantly increase both the microscopic lesions and inflammation.	23248206
Seizures, Torticollis, Meningitis	Altered Intercellular Communication	Presentation with torticollis and simple partial seizures resulting from diffuse leptomeningeal inflammation is rare.	23249509
Seizures, Inflammation, neuroborreliosis, Torticollis	Altered Intercellular Communication	As illustrated by this case neuroborreliosis can manifest itself atypically with torticollis, seizures and diffuse leptomeningeal enhancement due to inflammation.	23249509
Inflammation	Altered Intercellular Communication	Neutrophil-to-lymphocyte ratio (NLR) is a novel inflammation index that has been shown to independently predict poor clinical outcomes.	23249602
Inflammation, Angina Pectoris, Variant	Altered Intercellular Communication	Aerobic interval exercise training in the afternoon reduces attacks of coronary spastic angina in conjunction with improvement in endothelial function, oxidative stress, and inflammation.	23249633
Inflammation, SLC5A8 wt Allele, Angina Pectoris, Variant	Altered Intercellular Communication	AIT in the afternoon suppressed the attacks in conjunction with improvement in endothelial function, oxidative stress, inflammation, and insulin resistance in patients with coronary spastic angina.	23249633
Inflammation, EVP-0015962, Dental Plaque, Memory impairment	Altered Intercellular Communication	Chronic treatment with EVP-0015962 was well tolerated in mice and lowered the production of Ab42, attenuated memory deficits, and reduced Ab plaque formation and inflammation in Tg2576 transgenic animals.	23249765
Inflammation, Muscle (organ)	Altered Intercellular Communication	Muscle lesions and inflammation in futsal players according to their tactical positions.	23249823
Inflammation, Muscle (organ)	Altered Intercellular Communication	Thus, the purpose of this study was to characterize muscle lesion and inflammation in futsal players according to their positions in an official match.	23249823
Inflammation, Muscle damage	Altered Intercellular Communication	Goalkeepers showed higher LDH and IL-6 than players occupying other tactical positions, leading to the conclusion that the tactical position of futsal goalkeeper causes more inflammation and muscle damage than other positions.	23249823
Uterine Cervical Neoplasm, Inflammation	Altered Intercellular Communication	[The prevalence of abnormal cytology and inflammation and their association with risk factors for uterine cervical neoplasms in Cauca, Colombia].	23250315
Uterine Cervical Neoplasm, Inflammation	Altered Intercellular Communication	Establishing the prevalence of abnormal and inflammation cytology reports and its association with risks factors for uterine cervical neoplasms amongst females from the Cauca department in Colombia.	23250315
Lymphoid nodule, Fibrous, Inflammation	Altered Intercellular Communication	Histological examination of the implant revealed degradation on the medial side of the implant while the mass consisted of fibrous tissue with chronic inflammation and lymphoid follicle formation around a foreign material.	23250330
Inflammation, Abscess	Altered Intercellular Communication	Forms 3 and 4 of this pathology manifest themselves in the early childhood; they are frequently associated with inflammation and recurrence as well as the development of abscesses.	23250530
Suppuration, Inflammation	Altered Intercellular Communication	It was shown that only the complete removal of congenital parotid fistula prevents its inflammation and suppuration.	23250530
Inflammation, OSTF1 gene, Fibrosis Assessment	Altered Intercellular Communication	Oral submucous fibrosis (OSF) is a precancerous condition of oral mucosa with inflammation and progressive fibrosis of the lamina propria and deeper connective tissue.	23250779
Inflammation	Altered Intercellular Communication	The hypermethylation of E-cadherin and cyclooxygenase 2 (COX-2) in chronic inflammation may demonstrate a mild lesion/mutation at epigenetic levels.	23250779
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The epigenetic changes presented in patients with chronic inflammation might demonstrate an irreversible destruction in the tissues or organs similar to the effects of cancer.	23250779
Inflammation, Neoplasms	Altered Intercellular Communication	A proinflammatory cytokine, interleukin 23 (IL-23), plays a role in tumor progression by inducing inflammation in the tumor microenvironment, although there is debate about its role in carcinogenesis.	23250909
Inflammation, Heart failure, Endothelial dysfunction	Altered Intercellular Communication	Resting heart rate and incident heart failure and cardiovascular mortality in older adults: role of inflammation and endothelial dysfunction: the PROSPER study.	23250912
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Increased heart rate is associated with increased systemic inflammation and endothelial dysfunction.	23250912
Inflammation, Gastritis, Atrophic	Altered Intercellular Communication	On the basis of the histological diagnosis, PCA-positive patients were divided into 4 groups: (1) 30 patients with chronic atrophic gastritis; they had high concentrations of PCA and gastrin and no detectable IFA; (2) 14 subjects with metaplastic gastric atrophy; they had high PCA, IFA, and gastrin; (3) 18 patients with nonspecific lymphocytic inflammation with increased PCA, normal gastrin levels, and absence of IFA; (4) 21 patients with multifocal atrophic gastritis with "borderline" PCA, normal gastrin, absence of IFA and presence of anti-Hp in 100% of the cases.	23251219
Communicable Diseases, Pleural Diseases, Inflammation	Altered Intercellular Communication	Ability of procalcitonin to discriminate infection from non-infective inflammation using two pleural disease settings.	23251353
Communicable Diseases, Inflammation	Altered Intercellular Communication	However, infection is often paralleled by tissue inflammation.	23251353
Pleurisy, effusion	Altered Intercellular Communication	Pleurodesis, often used to treat effusions, involves provocation of intense aseptic pleural inflammation.	23251353
Inflammation, Pleural Infection	Altered Intercellular Communication	1) Procalcitonin was significantly higher in patients with pleural infection compared with controls with non-infective effusions (n = 32 each group) that were case-matched for systemic inflammation as measured by CRP [median (25-75%IQR): 0.58 (0.35-1.50) vs 0.34 (0.31-0.42) ug/L respectively, p = 0.003].	23251353
Inflammation, talc	Altered Intercellular Communication	2) Talc pleurodesis provoked intense systemic inflammation, and raised serum CRP by 360% over baseline.	23251353
Communicable Diseases, Pleural Diseases, Inflammation	Altered Intercellular Communication	Procalcitonin is superior to CRP in distinguishing infection from non-infective pleural diseases, even when controlled for the level of systemic inflammation.	23251353
Acute Lung Injury, Inflammation	Altered Intercellular Communication	Inflammation and immune-related candidate gene associations with acute lung injury susceptibility and severity: a validation study.	23251429
Acute Lung Injury, Inflammation	Altered Intercellular Communication	Common variants in genes related to inflammation, innate immunity, epithelial cell function, and angiogenesis have been reported to be associated with risks for Acute Lung Injury (ALI) and related outcomes.	23251429
Acute Lung Injury, Inflammation	Altered Intercellular Communication	These associations provide further evidence that genetic factors in genes related to immunity and inflammation contribute to ALI pathogenesis.	23251429
Inflammation, Mental deterioration, Obesity, Abdominal, Impaired cognition	Altered Intercellular Communication	We investigated the relation between cognitive impairment and metabolic deteriorations, low physical fitness, low-grade inflammation and abdominal obesity in middle aged individuals.	23251434
Inflammation, Obesity	Altered Intercellular Communication	Measurements of blood glucose, obesity and inflammation were not associated with cognitive function.	23251434
Inflammation, Atherosclerosis, Immune System Diseases, HIV Infections	Altered Intercellular Communication	HIV infection is associated with an increased risk of age-related morbidity mediated by immune dysfunction, atherosclerosis and inflammation.	23251521
Eye, Infiltration, Inflammation	Altered Intercellular Communication	Multifocal intrastromal infiltration, with relatively quiet ocular reaction and mild inflammation were initially presented in all eyes.	23252209
Neoplasms, Chronic sclerosing sialadenitis	Altered Intercellular Communication	Kuttner tumor or chronic sclerosing sialadenitis is a benign inflammatory condition of the salivary gland.	23253027
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Inflammation plays a crucial role in the pathogenesis and prognosis of stroke.	23253530
Inflammation	Altered Intercellular Communication	Relative to plain images, the high negative per cent agreement for normal glands suggests that, if an abnormal finding is detected on CBCT images, then disease can be ruled in, and the high positive per cent agreement for glands with inflammatory changes suggests that inflammation can be ruled out if these changes are not seen on CBCT images.	23253564
Inflammation, Neoplasms	Altered Intercellular Communication	Nevertheless, this interesting hypothesis and the role of inflammation in tumor biology remain complex and incompletely sure.	23254959
Rheumatoid Arthritis, Osteitis, Synovitis	Altered Intercellular Communication	Synovitis and bone inflammation in early rheumatoid arthritis: high-resolution multi-pinhole SPECT versus MRI.	23255070
Rheumatoid Arthritis, Osteitis, Synovitis	Altered Intercellular Communication	We aimed to assess the relationship between bone inflammation in multi-pinhole single-photon emission computed tomography (MPH-SPECT) and synovitis detected by magnetic resonance imaging (MRI) in early rheumatoid arthritis patients.	23255070
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Presence of joint inflammation in MRI was investigated using the subscores of the rheumatoid arthritis MRI score.	23255070
Depressive disorder	Altered Intercellular Communication	One carbon metabolism in the CNS plays a critical role in the synthesis and release of neurotransmitters which are relevant to depressive disorder.	23255668
Inflammation, Neuromyelitis Optica	Altered Intercellular Communication	CSF high-mobility group box 1 is associated with intrathecal inflammation and astrocytic damage in neuromyelitis optica.	23255728
Inflammation, N-nitrosomorpholine	Altered Intercellular Communication	HMGB1 could play a key role in central nervous system inflammation in NMO patients.	23255728
Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Purpura	Altered Intercellular Communication	Leukocytoclastic vasculitis (LCV) usually presents palpable purpura characterized by inflammation of vessel walls and fragmentation of nuclei.	23255867
Acute and chronic inflammation	Altered Intercellular Communication	While traditional cardiovascular risk factors and the effects of HIV and chronic inflammation all play a role, the contribution of long-term exposure to antiretroviral (ARV) agents is becoming clear.	23256968
Inflammation, Sleep Apnea, Obstructive, Airway Obstruction, Enlargement of tonsil or adenoid	Altered Intercellular Communication	We identified more severe obstructive sleep apnoea in clinically referred children during winter and spring and suggest that inflammation from respiratory viruses may contribute to adenotonsillar hypertrophy, worsening airway obstruction.	23257064
Airway structure, ARCN1 gene	Altered Intercellular Communication	Inhaled pan-selectin antagonist Bimosiamose attenuates airway inflammation in COPD.	23257347
Airway structure	Altered Intercellular Communication	It led to an attenuation of airway inflammation (EudraCT 2009-017257-35; NCT ID: NCT01108913).	23257347
Inflammation, Benign prostatic hypertrophy, Obesity	Altered Intercellular Communication	Inflammation is postulated to link obesity and benign prostatic hyperplasia (BPH).	23257365
Inflammation, Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	The association of chronic inflammation with the development of MALT lymphomas has been widely accepted.	23257674
Inflammation, PDR gene, Vitreous strands	Altered Intercellular Communication	The elevated IL-6 and IL-8 levels in vitreous, but not in plasma, are evidence favouring local over systemic inflammation in PDR.	23257933
Inflammation	Altered Intercellular Communication	Increased apoptosis along with enhanced inflammation has been reported in hemodialysis and pre-dialysis patients.	23258075
Tumor necrosis, Inflammation	Altered Intercellular Communication	Serum levels of C-reactive protein, tumor necrosis factor-a (TNF-a), interleukin-6 and plasma levels of fibrinogen were measured as markers of inflammation.	23258075
Inflammation, PBK gene, Keratopathy	Altered Intercellular Communication	According to some studies, inflammation is a potential etiological factor in pseudophakic bullous keratopathy (PBK).	23258303
Inflammation, Gout	Altered Intercellular Communication	Acute gout is associated with a decrease in serum uric acid (SUA) that is considered to be in response to acute inflammation but it may be a feature of gout itself.	23258648
Inflammation	Altered Intercellular Communication	Histology showed that there was prominent histiocytic inflammation with granular acellular eosinophilic components.	23259725
Inflammation	Altered Intercellular Communication	Interestingly, out of the 26 patients with fibrotic changes, 22 (85%) had positive pulmonary PET findings, of whom 18/22 (82%) showed extrathoracic PET-positive lesions and 16/22 (73%) showed signs of serological inflammation.	23261309
Tissue Adhesions, Inflammation, Hemorrhage, Respiration Disorders, Injury of bile duct	Altered Intercellular Communication	The reasons for the conversion consisted of adhesions (15 cases), inflammation (8 cases), adhesion plus inflammation (9 cases), bleeding (8 cases), common bile duct injury (4 cases), suspected common bile duct injury (1 case), injury of the duodenal bulb (1 case) and respiratory disorder (1 case).	23263446
Cataract, Pain Distress Question, Inflammation	Altered Intercellular Communication	It typically presents within 24 h of uncomplicated cataract surgery with minimal or no pain and intense anterior segment inflammation (Monson et al.	23263731
vascular inflammations, Calcinosis	Altered Intercellular Communication	Our data demonstrated the longitudinal progressions of vascular inflammation and calcification of health-screening subjects.	23264081
Inflammation, Calcinosis	Altered Intercellular Communication	Inflammation and calcification were observed to progress significantly faster in the abdominal aorta than in the thoracic aorta.	23264081
vascular inflammations, Calcinosis	Altered Intercellular Communication	The progressions of vascular inflammation and calcification may be associated with different atherogenic risk factors.	23264081
Inflammation, Aneurysm, Ruptured	Altered Intercellular Communication	Assessment of the inflammation and neovascularization in the wall and thrombus of the AAA might be an important factor in monitoring the progression and the risk of aneurysm's rupture.	23264218
Inflammation	Altered Intercellular Communication	One of the essential changes in inflammation is adhesion of leukocyte to endothelium and transmigration of leukocytes to the sites of inflammation.	23264403
Cholangitis	Altered Intercellular Communication	Histological re-examination identified immunoglobulin G4-related sclerosing cholangitis (n = 2) and nonspecific fibrosis/inflammation (n = 3).	23265129
Inflammation, Tissue Adhesions	Altered Intercellular Communication	However, inflammation, adhesions, and anatomic difficulty continue to challenge the use and safety of this approach in a small number of patients.	23265130
Inflammation, Rupture	Altered Intercellular Communication	Histologically unstable asymptomatic carotid plaques have altered expression of genes involved in chemokine signalling leading to localised plaque inflammation and rupture.	23265682
Degenerative polyarthritis, Inflammation, Obesity	Altered Intercellular Communication	Obesity is associated with osteoarthritis and it is accompanied by chronic inflammation and elevated oxidative stress.	23266138
Inflammation, Pain Distress Question, Osteoarthritis, Knee	Altered Intercellular Communication	Isokinetic exercise produces minimal inflammation and pain in knee osteoarthritis patients, could be performed every 48h during rehabilitation, and up-regulates patients' antioxidant system.	23266138
Inflammation, Congenital arteriovenous malformation	Altered Intercellular Communication	Microvascular proliferations in arteriovenous malformations relate to high-flow characteristics, inflammation, and previous therapeutic embolization of the lesion.	23266341
Inflammation, Thrombosis	Altered Intercellular Communication	Resection specimens of 80 AVMs were clinically categorized as either high- or low-flow lesions, and histopathologically screened for the presence of microvessels, inflammation, thrombosis, or a combination of these.	23266341
Inflammation, Thrombosis	Altered Intercellular Communication	In high-flow lesions, which were embolized before surgery (30% of all), 88% showed microvascular proliferation, 88% inflammation, and 33% thrombosis.	23266341
Inflammation, Depression, CTCAE	Altered Intercellular Communication	CONTEXT The pathogenesis of depression is not fully understood, but studies suggest that low-grade systemic inflammation contributes to the development of depression.	23266538
malignant disease, Inflammation	Altered Intercellular Communication	MDSCs seem to play an important role in inflammation that is strongly related to advancing malignant diseases.	23267986
Inflammation	Altered Intercellular Communication	[The treatment of the patients presenting with chronic inflammation of the trepanation cavity with a preparation containing silver nanoparticles following sanitation surgery of the open type].	23268263
Inflammation, Malignant Neoplasms, Goblet cell of small intestine	Altered Intercellular Communication	A background of chronic inflammation increases the frequency of expression of an intestinal goblet-cell phenotype and p53 in the cancers.	23268317
Inflammation, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	Our results demonstrated that the cause of anemia was iron deficiency, chronic inflammation, or chronic kidney disease in 75% of the patients, and that anemia was improved in more than 80% of the patients after appropriate therapeutic treatment.	23268911
Granulomatous inflammation	Altered Intercellular Communication	The tonsils are uncommonly affected by granulomatous inflammation.	23269077
Necrotizing granulomatous inflammation	Altered Intercellular Communication	This study attempted to clarify the clinicopathological and immunohistochemical findings and presence or absence of Epstein-Barr virus (EBV) in tonsilar granulomatous inflammation.	23269077
Idiopathic Inflammatory Myopathies, Inflammation, Paresis, Myopathy	Altered Intercellular Communication	The idiopathic inflammatory myopathies (IIM) are acquired muscle diseases characterized by muscle weakness and inflammation on muscle biopsy.	23269233
Inflammation, Acute inflammation	Altered Intercellular Communication	A total of 82 % of patients had chronic low-grade inflammation of the gallbladder wall and 18.0 % had acute inflammatory exacerbations.	23270822
Inflammation	Altered Intercellular Communication	From our study, we found chronic and/or intermittent cystic duct obstructions and low-grade GB wall inflammation lead to GB epithelium hydrogen secretion dysfunction.	23270822
Inflammation, Hemorrhage, Dental Plaque, Rupture	Altered Intercellular Communication	Seven histological features of plaque instability (haemorrhage, large lipid core, chronic plaque inflammation, chronic cap inflammation, marked vascularity, cap rupture and many foam cells) were independently quantified and then correlated with recency of symptoms in patients undergoing CEA.	23270859
Inflammation, Hemorrhage, Rupture	Altered Intercellular Communication	However, there was then a marked increase in the prevalence of plaque haemorrhage (59% up to 65%), large lipid core (41% up to 78%), chronic plaque inflammation (71% up to 91%), cap rupture (35% up to 39%), many foam cells (24% up to 43%) and marked vascularity (71% up to 91%) in 23 patients undergoing CEA after 29 days had elapsed.	23270859
Inflammation, Corneal edema	Altered Intercellular Communication	In all patients, active inflammation and corneal edema resolved within 6 weeks, and visual outcome was 20/20.	23271338
Inflammation, Sacroiliac joint structure, Peripheral, Spondylitis	Altered Intercellular Communication	Ankylosing spondylitis (AS) is a chronic inflammation of the sacroiliac joints, spine and peripheral joints.	23272049
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Toll like receptor 4 (TLR4) has been related to inflammation and beta-amyloid deposition in Alzheimer's disease (AD) brain.	23272070
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Association of the innate immunity and inflammation pathway with advanced prostate cancer risk.	23272139
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Innate immunity and inflammation may increase the risk of prostate cancer.	23272139
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Our results suggest that the innate immunity and inflammation pathway may play a modest role in the etiology of advanced prostate cancer through multiple small effects.	23272139
Chronic infectious disease, Inflammation	Altered Intercellular Communication	Chronic infection may induce persistent inflammation of the tissue and secondarily, a cancerization process within a few years.	23272143
Inflammation	Altered Intercellular Communication	Eosinophils (Eo) are one type of the major proinflammatory cells of the chronic inflammation in the intestine.	23272174
Eosinophilic disorder, Inflammation, Fibrillary glomerulonephritis	Altered Intercellular Communication	After treatment with FGN intrarectally, mice with eosinophilia showed severe inflammation in the colon.	23272174
Gastrointestinal inflammation	Altered Intercellular Communication	The interaction of galectin 3 and CD98 can induce Eos to release chemical mediators that contributes to the initiation of the intestinal inflammation.	23272174
Necrotizing enterocolitis in fetus OR newborn, Gastrointestinal inflammation	Altered Intercellular Communication	Multiple pro- and anti-inflammatory cytokines have been identified as markers of intestinal inflammation, both in human patients with NEC and in models of immature intestine.	23272193
Inflammation, Dysbiosis, Necrotizing enterocolitis in fetus OR newborn	Altered Intercellular Communication	Specifically, IL-10 signaling attenuates intestinal responses to gut dysbiosis, and disruption of this pathway exacerbates inflammation in murine models of NEC.	23272193
Vascular insufficiency of intestine, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We have developed an accurate bioassay utilizing proteins representing four central pathogenetic modalities of the disease: lymphangiogenesis, inflammation, fibrosis, and lipid metabolism, suggesting that these proteins are directly related to the pathogenesis of the tissue pathology in lymphatic vascular insufficiency.	23272198
Inflammation, AHSG protein, human	Altered Intercellular Communication	Fetuin-A is a liver protein that may serve as an inhibitor of systemic inflammation in humans.	23272665
Inflammation, doxorubicin/procarbazine/vincristine protocol	Altered Intercellular Communication	PTX3 was not superior to CRP as a biomarker to diagnose VAP, but it was an early indicator of inflammation and had better prognostic value to predict mortality than CRP.	23273657
doxorubicin/procarbazine/vincristine protocol	Altered Intercellular Communication	The PTX3 values increase rapidly during multiple inflammatory conditions, but little is known about its characteristics in VAP.	23273657
Inflammation, Ischemic stroke, atherosclerotic	Altered Intercellular Communication	Our data show that M1 macrophage content of atherosclerotic plaques is associated with clinical incidence of ischemic stroke and increased inflammation or fibrinolysis.	23273713
Compartment syndromes, Inflammation, Myositis, CTCAE 5.0	Altered Intercellular Communication	The severity of the inflammation resulted in a forearm myositis secondarily causing a compartment syndrome that was treated with several prolonged courses of corticosteroids.	23274380
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Genetic variants of the serotonergic neurotransmitter system are potential contributing factors in the pathological processes underlying Alzheimer's disease (AD).	23274704
Granulomatous inflammation, Enteritis, Crohn Disease	Altered Intercellular Communication	Colonoscopy showed active enteritis with granulomatous inflammation consistent with Crohn's disease (CD).	23274739
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is associated with chronic severe airway inflammation and causes increasing global health problems.	23275209
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Inflammation might influence muscle strength in patients with knee OA.	23275388
Inflammation, Obesity	Altered Intercellular Communication	Moreover, the link between inflammation and obesity might explain the effect that BMI has in the associations between inflammatory markers (i.e.	23275388
Inflammation, Chronic diarrhea	Altered Intercellular Communication	Nonspecific changes (nonspecific chronic inflammation) in patients with chronic diarrhea represent the commonest diagnosis in colorectal biopsy interpretation, but these changes are of little clinical significance.	23276179
Inflammation, Eosinophilic inflammation	Altered Intercellular Communication	In AIG, inflammation was characterised by lymphocyte infiltration into the epithelium (98%), basal lymphoid aggregates (82.7%), basal predominance (59.6%), eosinophil infiltration [mean 34.5/high power field (HPF), >30 eosinophils/HPF in 46.1%] and neutrophil infiltration (44.2%).	23277173
Inflammation, Pancreatic aplasia, Eosinophilic inflammation	Altered Intercellular Communication	Compared to NGB, HPG, MAG and CG, AIG displayed more eosinophil infiltration (p < 0.001) and more frequent lymphocyte infiltration of the epithelium, basal predominant inflammation and pancreatic acinar metaplasia (all p > 0.05).	23277173
Inflammation, Compressed structure	Altered Intercellular Communication	If intravitreal antibiotics fail to control inflammation, early pars plana vitrectomy and silicone oil tamponade would be an appropriate option.	23277209
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The explanation for this chronic inflammation remains unclear, but may result from an impaired ability of alveolar macrophages to phagocytose apoptotic cells (a process termed 'efferocytosis'), as we have shown in chronic obstructive pulmonary disease (COPD).	23278878
ARCN1 gene, Inflammation, Asthma, Airway structure	Altered Intercellular Communication	Macrophage efferocytosis is impaired in non-eosinophilic asthma to a similar degree as that in COPD and may explain the persistent airway neutrophilia and chronic inflammation that characterizes this asthma subtype.	23278878
Inflammation, Diabetic Angiopathies	Altered Intercellular Communication	Complement-mediated chronic inflammation is associated with diabetic microvascular complication.	23280928
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Chronic inflammation is characteristic of type 2 diabetes mellitus (T2DM).	23280928
Inflammation, Microangiopathy, Diabetic	Altered Intercellular Communication	We investigated the association between diabetic microangiopathy and complement-mediated inflammation in 32 obese T2DM patients and 32 normal donors.	23280928
Inflammation	Altered Intercellular Communication	Activation of the alternative complement pathway occurs in obese T2DM patients and is enhanced in the post-prandial hyperchylomicronic condition, which induces overproduction of ASP and C3a-mediated tissue inflammation.	23280928
Inflammation, Microangiopathy, Diabetic, macroangiopathy	Altered Intercellular Communication	Therefore, complement-mediated inflammation may contribute to the acceleration of diabetic microangiopathy in addition to the development of macroangiopathy.	23280928
Inflammation	Altered Intercellular Communication	RRMS patients showed higher CST Cho concentration than controls, and higher CST Ins concentration than PPMS, suggesting greater inflammation and glial proliferation in the RR than in the PP course.	23281189
Disability, Inflammation	Altered Intercellular Communication	In PPMS, lower CST Cho and Cr concentrations correlated with greater disability, suggesting that in the progressive stage of the disease, inflammation declines and energy metabolism reduces.	23281189
Inflammation, Atherosclerosis	Altered Intercellular Communication	Associations among lung function, arterial elasticity, and circulating endothelial and inflammation markers: the multiethnic study of atherosclerosis.	23283358
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Endothelial dysfunction and inflammation could potentially decrease elasticity of both vasculature and lung tissue.	23283358
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Spirometric data and markers of endothelial dysfunction and inflammation (soluble intracellular adhesion molecule-1, fibrinogen, hs-C-reactive protein, and interleukin-6) were obtained.	23283358
Inflammation	Altered Intercellular Communication	Inflammation was generally more frequent in the metatarsophalangeal (MTP) joints (221/292; 76 %) than in the proximal metatarsal (47/292; 16 %) and tarsal bones (24/292; 8 %).	23283542
Refractory anemias, Inflammation	Altered Intercellular Communication	Progress of inflammation in the MTP 1 was more frequently found in ERA patients than in patients with established RA (disease duration >12 months) (p = 0.002).	23283542
Inflammation	Altered Intercellular Communication	As a key encoding protein gene of MRN (MRE11-RAD50-NBS1) complex, NBS1 plays a crucial role in maintaining genomic stability and preventing cell apoptosis, inflammation and tumorgenesis.	23283743
Inflammation, Psoriasis, Inflammatory dermatosis, Hyperplasia, Histopathologic Grade differentiation	Altered Intercellular Communication	Psoriasis, a common inflammatory skin disease, is characterized by epidermal hyperplasia, abnormal differentiation, angiogenesis, immune activation, and inflammation.	23283814
Inflammation, Sleep Apnea Syndromes, Coronary Artery Disease, Dyslipidemias	Altered Intercellular Communication	Sleep apnoea, a frequent comorbidity of T2DM women, is associated with central fat, atherogenic dyslipidaemia, inflammation, worsening b-cell function, poorer glycaemic control and coronary artery disease risk.	23283827
Inflammation, Peritonitis	Altered Intercellular Communication	Peritoneal protein leakage, systemic inflammation, and peritonitis risk in patients on peritoneal dialysis.	23284072
Inflammation, Peritonitis	Altered Intercellular Communication	Baseline peritoneal protein leakage was able to independently predict risk for peritonitis, which is not explained by systemic inflammation.	23284072
Inflammation, Atherosclerosis	Altered Intercellular Communication	The role of inflammation in atherosclerosis is widely appreciated.	23284878
Inflammation, Atherosclerosis	Altered Intercellular Communication	High mobility group box 1 (HMGB1), an injury-associated molecular pattern molecule acting as a mediator of inflammation, has recently been implicated in the development of atherosclerosis.	23284878
Cessation of life, Inflammation, Malnutrition	Altered Intercellular Communication	Furthermore, low s-Mg and high s-Ca levels were independently associated with malnutrition, inflammation, arterial stiffening and risk of death.	23285003
Conjunctivitis	Altered Intercellular Communication	Clinically visible conjunctival inflammation was associated with increased S100A7, IL1B, CXCL5, MMP9 and MMP12 expression.	23285311
Inflammation, Pleural effusion disorder	Altered Intercellular Communication	Pentraxin-3 (PTX-3) is a relatively new marker of inflammation that has not been previously tested in pleural effusions.	23286371
Autoimmune hypoparathyroidism	Altered Intercellular Communication	Late primary autoimmune hypothyroidism in a patient with postdelivery autoimmune hypopituitarism associated with antibodies to growth hormone and prolactin-secreting cells.	23286389
Inflammation, Spasm	Altered Intercellular Communication	Although nonculprit artery perfusion may be improved after successful primary PCI, it is still lower than that in the control group, and may be involved in inflammation and spasms.	23286472
Granulomatous inflammation, Infection	Altered Intercellular Communication	Diagnosis is by clinical and histopathologic exclusion of other entities, which include other causes of granulomatous inflammation such as infections and foreign-body reactions.	23286800
Inflammation, Myopathy	Altered Intercellular Communication	Distal myopathy with rimmed vacuoles and inflammation: a genetically proven case.	23287327
Weakness, Inflammation	Altered Intercellular Communication	We report the first genetically proven case of DMRV from India in a 23-year-old male with gradual onset, progressive distal weakness of both lower limbs with features of inflammation in muscle biopsy.	23287327
Inflammation, Degenerative disorder	Altered Intercellular Communication	Bowman lecture on the role of inflammation in degenerative disease of the eye.	23288138
Inflammation	Altered Intercellular Communication	Inflammation, in the pathogenesis of many diseases previously thought to be strictly genetic, degenerative, metabolic, or endocrinologic in aetiology, has gradually entered the framework of a general mechanism of disease.	23288138
Inflammation	Altered Intercellular Communication	However, inflammation itself is not easy to define, and some aspects of inflammation may be beneficial, in a process described as 'para-inflammation' by Medhzitov.	23288138
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	High-mobility group box 1 (HMGB1), a DNA-binding cytokine expressed mainly by macrophages, contributes to lesion progression and chronic inflammation within atherosclerotic plaque.	23288170
Inflammatory Bowel Diseases	Altered Intercellular Communication	Here, we hypothesize that overexpression of miR-155 and miR-21, two inflammation-related microRNAs that target core MMR proteins, may constitute a pre-neoplastic event for the development of MSI IBD CRCs.	23288924
Inflammation, Congenital Abnormality	Altered Intercellular Communication	Patients undergoing hemodialysis (HD) have low plasma levels of zinc (Zn), high plasma levels of copper (Cu), and exhibit increased oxidative stress, inflammation, and immune abnormalities.	23289009
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	As a result of clinical, radiological and laboratory studies of the patients with granulomatous inflammation, 13 (38.2%) patients had TB, 21 (61.7%) patients had sarcoidosis.	23289466
Inflammation, Fibrosis Assessment, Pneumonia, Interstitial	Altered Intercellular Communication	The computerised tomography guided lung biopsy was reported as nonspecific interstitial pneumonia, liver biopsy was reported as portal inflammation and fibrosis.	23289468
Sample Size Calculation, Arthritis, Inflammation	Altered Intercellular Communication	The distribution, the MRI pattern and the predilection for the lunate bone raise the hypothesis that arthritis in SSc may be caused not only by immunological inflammation but also by ischemic mechanisms.	23289906
Airway structure, Exacerbation of asthma	Altered Intercellular Communication	The combination of theophylline plus SFC may provide greater protection against asthma exacerbations, and its administration is accompanied by significant improvements in small airway function and airway inflammation.	23290154
Inflammatory abnormality of the eye	Altered Intercellular Communication	The severity of ocular inflammation identified ranged from mild to severe AAU and thus required several weeks of treatment.	23290982
Inflammation, Coronary Arteriosclerosis, physiopathological, Diabetes Mellitus	Altered Intercellular Communication	This study demonstrates a close association between elevated levels of highly pro-inflammatory eicosonoids, diabetes and EPC dysfunction in patients with cardiac ischemia, indicating that chronic inflammation impact negatively on EPC function and angiogenic capacity in diabetes.	23291334
Inflammation, Anemia	Altered Intercellular Communication	Effect of ultrapure dialysate on markers of inflammation, oxidative stress, nutrition and anemia parameters: a meta-analysis.	23291370
Inflammation, Malnutrition	Altered Intercellular Communication	Markers of inflammation are linked to malnutrition and confer an increased mortality risk in hemodialysis patients.	23291370
Inflammation	Altered Intercellular Communication	Other markers of inflammation and oxidative stress displayed similar significant improvements.	23291370
Inflammation	Altered Intercellular Communication	18F-fluorodeoxy glucose-positron emission tomography imaging showed significantly increased uptake by the LV and right ventricular walls, indicating active inflammation.	23291676
Acute inflammation, Cardiac sarcoidosis	Altered Intercellular Communication	The final diagnosis was thus cardiac sarcoidosis with acute inflammation.	23291676
Inflammation, Acute heart failure, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	This is a rare case in which acute inflammation led to acute heart failure mimicking acute myocarditis.	23291676
Arterial Stiffness, Inflammation	Altered Intercellular Communication	The AIx showed a significant positive correlation (r=0.28; p<0.001) with the serum high-sensitivity C-reactive protein concentration, as a marker of inflammation; with the urinary 8-iso-prostaglandin F2a concentration (r=0.31; p<0.001), as a marker of oxidative stress; and with the cardio-ankle vascular index (r=0.17; p<0.01), as a marker of systemic arterial stiffness.	23291840
Inflammation	Altered Intercellular Communication	These findings indicate that the AIx reflects inflammation, oxidative stress, and the urinary albumin concentration in patients with preserved kidney function.	23291840
Inflammation, Helicobacter pylori, Carcinogenesis	Altered Intercellular Communication	Chronic inflammation triggered by Helicobacter pylori causes altered DNA methylation in stomach mucosae, which is deeply involved in gastric carcinogenesis.	23292007
Gastritis	Altered Intercellular Communication	Methylation levels of the six CpG islands were consistently increased, and those of the two repetitive elements were consistently decreased in a stepwise manner with the activity of gastric inflammation as represented by serum marker levels.	23292007
Inflammation, Asthma	Altered Intercellular Communication	These novel findings suggest that rs12932187 and rs11074938 may constitute susceptibility markers of inflammation of the nasal passages in asthma patients.	23292525
Carcinoma of lung	Altered Intercellular Communication	Genetic single-nucleotide polymorphisms of inflammation-related factors associated with risk of lung cancer.	23292870
Orbital Pseudotumor	Altered Intercellular Communication	To identify and characterize patients with orbital masses in a monocentric cohort of 1142 GPA patients followed up from 1990 until the end of 2010 with regard to disease stage, local orbital inflammation, course of disease and outcome and to assess the efficacy of immunosuppressive treatment.	23293138
Inflammation, Autoimmune Chronic Hepatitis, Hepatitis	Altered Intercellular Communication	Liver biopsy was also typical of autoimmune hepatitis as attested by the presence of portal inflammation with predominant T-lymphocytes and plasma cells and interface hepatitis.	23293207
Inflammation, HIV Infections, SHD gene	Altered Intercellular Communication	SHD is frequent and correlates with inflammation in HIV infected patients.	23295013
Inflammation	Altered Intercellular Communication	The inflammation class (38% of ICCs) is characterized by activation of inflammatory signaling pathways, overexpression of cytokines, and STAT3 activation.	23295441
Inflammation	Altered Intercellular Communication	The inflammation class (38% of ICCs) is characterized by activation of inflammatory signaling pathways, overexpression of cytokines, and STAT3 activation.	23295441
Inflammation, Neoplasms	Altered Intercellular Communication	Inflammation is an important biological process involved in the development of many solid tumors.	23295727
Calculus of prostate, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	Lower urinary tract symptoms in benign prostatic hyperplasia patients: orchestrated by chronic prostatic inflammation and prostatic calculi?.	23295780
Calculus of prostate, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	This study aims to examine the relationship between chronic prostatic inflammation and prostatic calculi, and clinical parameters of benign prostatic hyperplasia (BPH).	23295780
Inflammation	Altered Intercellular Communication	Chronic inflammation was graded as 0 (n = 44), I (n = 54), II (n = 88) or III (n = 39) according to severity.	23295780
Inflammation, Calculi	Altered Intercellular Communication	The relationship between inflammation and calculus type was analyzed, and clinical parameters of BPH were compared for each group.	23295780
Inflammation, Calculi	Altered Intercellular Communication	There was no correlation between severity of inflammation and calculus type.	23295780
Inflammation	Altered Intercellular Communication	Prostatic volume increased with the severity of inflammation and showed significant differences between G2, G3 and G0.	23295780
Inflammation	Altered Intercellular Communication	The International Prostate Symptom Score also increased with increasing inflammation.	23295780
Calculus of prostate, Inflammation	Altered Intercellular Communication	Prostatic calculi had no significant association with chronic inflammation and clinical parameters of BPH.	23295780
Inflammation	Altered Intercellular Communication	Chronic inflammation was associated with the volume of the prostate and storage symptoms; thus, it is not only presumed to be related to the progression of BPH, but may also be one of the causes of lower urinary tract symptoms.	23295780
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	In recent years, evidence has emerged indicating that insulin resistance and diabetes mellitus type 2 are associated with inflammation of adipose tissue (AT).	23296264
Malignant neoplasm of urinary bladder, Inflammation, Obesity, Abdominal, Diabetes Mellitus	Altered Intercellular Communication	We also observed a synergistic interaction between diabetes and high WHR in bladder cancer development that might be explained by increased insulin resistance and inflammation related to abdominal obesity.	23296458
Respiratory Failure, Pneumonitis	Altered Intercellular Communication	FiO2 0.40 in mechanically ventilated patients without severe respiratory failure did not increase systemic or pulmonary inflammation.	23296630
Inflammation	Altered Intercellular Communication	Histological investigation of the appendix revealed transmural acute inflammation, with diffuse proliferation of inflammatory cells, with characteristic intranuclear inclusion surrounded by a clear halo.	23297526
Inflammation, Uveitis	Altered Intercellular Communication	The dexamethasone (Ozurdex) implant seems comparable to the fluocinolone acetonide (Retisert) implant in preventing recurrence of noninfectious uveitis and in improving inflammation and BCVA.	23297752
Degenerative polyarthritis, Inflammation, Chondromalacia Patellae, Pain Distress Question	Altered Intercellular Communication	Osteoarthritis is characterized by progressive articular cartilage degeneration, changes in subchondral bone and synovial inflammation, leading to pain and disability.	23298499
Liver and Intrahepatic Biliary Tract Carcinoma, Inflammation	Altered Intercellular Communication	The mechanisms of progression in biliary tract cancer (BTC) with inflammation, including epithelial-mesenchymal transition (EMT), are not well understood.	23298711
Malignant Neoplasms, Neoplasms	Altered Intercellular Communication	We focused on two inflammation-associated cytokines, interleukin-6 (IL-6) and transforming growth factor-beta 1 (TGF-b1), and investigated their expression and activity, as well as their relationship to key features of malignancy, in tumour samples from patients with BTC and in cultured BTC cells.	23298711
Juvenile arthritis, Inflammation, Temporomandibular Joint, Soft tissue rheumatism, Juvenile rheumatoid arthritis	Altered Intercellular Communication	To differentiate between temporomandibular joint (TMJ) inflammation and myofascial pain (MPD) in children with juvenile idiopathic arthritis (JIA).	23298802
Arthritis, Myalgia, Asymmetry	Altered Intercellular Communication	Patients with clinical evidence (joint pain/tenderness, asymmetry, limited motion) and radiographic evidence (condylar asymmetry, flattening, accentuated antegonial notch) of TMJ inflammation but without muscle pain were diagnosed with arthritis.	23298802
Arthritis	Altered Intercellular Communication	Patients with TMJ inflammation and muscle pain/tenderness were considered to have co-existing arthritis and MPD.	23298802
Inflammation, Demographics Domain	Altered Intercellular Communication	In patients with type 2 DM, 12 weeks oral supplementation of vitamin D did not significantly affect vascular function or serum biomarkers of inflammation and oxidative stress.	23298824
Inflammation	Altered Intercellular Communication	Serum prealbumin is associated with short-term energy intake independently of the presence of multiple-organ involvement and inflammation.	23298969
Inflammation, Renal function	Altered Intercellular Communication	Its serum levels should be always interpreted in light of its influencing factors, among which inflammation and liver and kidney functions appear predominant.	23298969
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The association between nutritional status and inflammation was assessed in patients with colorectal cancer and to verify their association with complications during anticancer treatment.	23298973
Inflammation	Altered Intercellular Communication	The nutritional status was defined by the SGA and the severity of inflammation was defined by the Glasgow Prognostic Score (GPS).	23298973
Inflammation, Adult Non-Hodgkin Lymphoma	Altered Intercellular Communication	Non-hodgkin lymphoma and circulating markers of inflammation and adiposity in a nested case-control study: the multiethnic cohort.	23300021
Inflammation, RTEL1 gene, Obesity, Adult Non-Hodgkin Lymphoma, Immune System Diseases	Altered Intercellular Communication	Because immune dysfunction is thought to underlie the development of non-Hodgkin lymphoma (NHL), obesity and chronic inflammation may be involved in its etiology.	23300021
Inflammation, RTEL1 gene	Altered Intercellular Communication	Although markers of inflammation and adiposity may provide new insights into the etiology of NHL, they need to be assessed many years before clinical diagnosis.	23300021
Inflammation, Adverse reaction to drug	Altered Intercellular Communication	A punch biopsy of skin from the patient's right lower abdomen revealed perivascular chronic inflammation with numerous eosinophils consistent with drug reaction.	23300150
Lactobacillus, Inflammation, Colitis	Altered Intercellular Communication	Finally, this Lactobacillus strain reduced inflammation in a murine model of colitis.	23300685
Inflammation, Injury of kidney, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation is a pathogenic factor in renal injury, but whether inflammation is related to renal outcome in chronic kidney disease (CKD) patients is little known.	23300770
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We thus assess the association of inflammation and renal outcome in an advanced CKD cohort.	23300770
Inflammation	Altered Intercellular Communication	Activated microglia is characterized by increased expression of the 18 kDa translocator protein (TSPO) in the brain and may be a useful biomarker of inflammation.	23300829
Inflammation, Elastosis perforans serpiginosa	Altered Intercellular Communication	Patients in this group exhibited a lower index of systemic inflammation and a longer symptomatic period than in EPS patients with biopsies of the "mixed" type (p<0.05).	23300922
Cytomegalovirus Infections, Inflammation	Altered Intercellular Communication	Collaborative studies suggested that both activating and inhibitory KIR and functionally relevant MBL2 haplotypes are important factors for control of CMV infection in the elderly and therefore for chronic low-grade inflammation.	23302099
Inflammation	Altered Intercellular Communication	Currently thoughts that environment factors and genes, oxidative damage, inflammation, immune reaction, imbalance between angiogenesis factors and anti-angiogenesis factors, etc.	23302236
Intraocular Infection, Intraocular inflammation	Altered Intercellular Communication	The intraocular infection of all 20 eyes was controlled, and the intraocular inflammation was relieved.	23302273
Granulomatous inflammation, Thrombosis, Vasculitis, CTCAE, Necrosis	Altered Intercellular Communication	Deep-seated necrosis, granulomatous inflammation against fungal organisms (3/19) and vasculitis with thrombosis (4/19) were not common.	23302306
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation against fungal organisms were identified (16/16).	23302306
Inflammation, Depressed mood	Altered Intercellular Communication	In according with the down-regulated level of M-CSF, the polarization from M1 macrophages into M2 is depressed, and the inflammation induced by M1 is sustained.	23302467
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Depression has been associated with inflammation, and inflammation may both influence and interact with growth factors such as brain-derived neurotrophic factor (BDNF).	23303061
Inflammation, Pancreatitis, Duodenal Ulcer	Altered Intercellular Communication	The spread of inflammation associated with the duodenal ulcer may have been one of the causes of groove pancreatitis.	23303234
Inflammation, Asthma, Eosinophilic granulomatosis with polyangiitis, Vasculitis, CTCAE	Altered Intercellular Communication	The Churg-Strauss syndrome (CSS), first described in 1951 and characterised by eosinophilic inflammation and necrotising vasculitis in patients with asthma can in principle affect any organ.	23303591
Inflammation, Rupture, Atherosclerotic lesion, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	sEH inhibition regulated FAS and inhibited inflammation in cultured PBMCs from ACS patients, a mechanism that might prevent rupture of atherosclerotic lesions and protect against development of ACS.	23305094
Sepsis, Liver Abscess, Inflammation	Altered Intercellular Communication	Hepatic abscess should be suspected in neonates with UVC with sepsis and persistent signs of inflammation in spite of adequate antibiotic treatment.	23305752
Inflammation, Congenital anomaly of coronary artery	Altered Intercellular Communication	Compared with patients with typical KD, patients with NFKD were older, had more severe inflammation, and had similar rates of coronary artery abnormalities and resistance to intravenous immune globulin.	23305955
vascular inflammations	Altered Intercellular Communication	Markers of vascular inflammation were measured - before surgery and three months afterwards.	23306174
Inflammation, Benign prostatic hypertrophy, Necrosis	Altered Intercellular Communication	The prognostic use of inflammation and tissue necrosis in benign prostatic hyperplasia.	23306308
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Evidence for the role of inflammation in benign prostatic hyperplasia (BPH) is conflicting.	23306308
Inflammation, Necrosis	Altered Intercellular Communication	Establishing the prognostic significance of local and systemic inflammation and tissue necrosis scoring systems in BPH may elucidate the potential of inflammatory pathways as a target of therapeutic intervention in these patients.	23306308
Inflammation, Necrosis, Failure (biologic function)	Altered Intercellular Communication	In 392 BPH patients, there was a trend for increased local inflammation and tissue necrosis to be associated with shorter time to failure of pre-operative medical treatment of BPH (p = 0.096 and 0.088, respectively).	23306308
Inflammation, Necrosis	Altered Intercellular Communication	The prognostic use of established scoring systems of systemic and local inflammation and tissue necrosis in BPH requires further investigation.	23306308
Inflammation	Altered Intercellular Communication	Periradicular injections of meloxicam (10 mg) appear to be a useful alternative to opioid and non-opiod analgesics for patients with intractable LBP due to nerve root inflammation.	23306395
Inflammation, Pain Distress Question	Altered Intercellular Communication	Adding steroid to local anaesthetics in local infiltration analgesia reduced inflammation both locally and systemically, resulting in significant early pain relief and rapid recovery in total knee arthroplasty.	23306715
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Therefore, it appears that the inflammation tends to subside with age in elderly patients with long-standing UC.	23306844
Inflammation, Cardiovascular Diseases, Left Ventricular Hypertrophy, Ventricular hypertrophy	Altered Intercellular Communication	Micro inflammation and cardiovascular disease such as left ventricular hypertrophy (LVH) are common in hemodialysis (HD) patients.	23306861
Acute cholangitis, Inflammation, Cholestasis	Altered Intercellular Communication	The diagnostic criteria of acute cholangitis have been revised as criteria to establish the diagnosis where cholestasis and inflammation demonstrated by clinical signs or blood test in addition to biliary manifestations demonstrated by imaging are present.	23307001
Inflammation, Dryness (characteristic)	Altered Intercellular Communication	Sensitivity and specificity of a point-of-care matrix metalloproteinase 9 immunoassay for diagnosing inflammation related to dry eye.	23307206
Inflammation, Dryness (characteristic)	Altered Intercellular Communication	Preoperative and perioperative management of inflammation related to dry eyes may reduce dry eyes that develop after laser in situ keratomileusis, improve wound healing, and reduce flap complications.	23307206
Cataract, Inflammation	Altered Intercellular Communication	Recognition of inflammation may allow for targeted perioperative therapeutic management of care for patients who undergo cataract and refractive surgery and improve outcomes.	23307206
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The prognostic, especially predictive, values of inflammation indexes in advanced colorectal cancer were not established.	23307251
Malignant neoplasm of gastrointestinal tract	Altered Intercellular Communication	Arachidonic acid metabolic pathway has been implicated in the inflammation-associated tumorigenesis of gastrointestinal cancers.	23307260
Inflammation, Sacroiliac joint structure, Peripheral, Spondylitis	Altered Intercellular Communication	Ankylosing spondylitis (AS) is a chronic inflammation of the sacroiliac joints, spine and peripheral joints.	23308121
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Inflammation and the metabolic syndrome: clustering and impact on survival in a Swedish community-based cohort of 75 year olds.	23308380
Unknown (origin) (qualifier value), Pneumonitis	Altered Intercellular Communication	The variation in accumulated DC-SIGN-positive cells might help to explain the differences in the development and maintenance of lung inflammation between idiopathic UIP and CVD-UIP.	23311128
palladium	Altered Intercellular Communication	Our study showed that PA declines significantly in PD patients, which might correlate with malnutrition-inflammation-atherosclerosis syndrome.	23311233
Airway structure, Lung diseases	Altered Intercellular Communication	Induced sputum is a non-invasive sampling technique for the analysis of airway inflammation in various lung diseases and comprises valuable potential for the identification of biomarkers and therapeutic targets by molecular methods.	23312618
Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Concomitant cytomegalovirus and non-necrotizing granulomatous inflammation were also observed.	23312917
Disability Assessment for Dementia Questionnaire, Hematoxylin and eosin stain method, Alveolar damage, Bronchiolitis, Acute Lung Injury, Vasculitis	Altered Intercellular Communication	The biopsy H&E slides were reviewed in a blinded fashion, and scored for presence of microvascular inflammation, acute rejection, bronchiolar inflammation and acute lung injury, as well as diffuse alveolar damage (DAD).	23313559
Vasculitis	Altered Intercellular Communication	Microvascular inflammation was graded by the presence of capillary neutrophils on a scale of 0 to 4(+).	23313559
Inflammation, Fatigue	Altered Intercellular Communication	Fatigue, low grip strength and markers of systemic inflammation were associated with short walking distance (P < 0.05).	23314651
Inflammation, Weight decreased, Fatigue	Altered Intercellular Communication	Weight loss, fatigue and markers of systemic inflammation were most strongly and consistently associated with adverse QoL, reduced functional abilities, more symptoms and shorter survival.	23314651
Conjunctival hyperemia	Altered Intercellular Communication	A second review of the false-positive cases' pCLE sequences (benign inflammatory) helped refine the existing classification by identifying four descriptive criteria specific to benign inflammatory conditions (Paris Classification): Vascular congestion, dark granular patterns with scales, increased inter-glandular space, and thickened reticular structure.	23314855
Inflammation	Altered Intercellular Communication	Decreased cingulate expression of EPHB2 may represent a compensatory mechanism minimizing excitotoxic injury in the face of chronic inflammation.	23314923
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Punch skin biopsy as well as sural nerve biopsy demonstrated chronic granulomatous inflammation without evidence of Mycobacterium.	23315459
Fibrosis Assessment, Chronic lung disease	Altered Intercellular Communication	Cystic Fibrosis (CF) is a chronic lung disease characterized by chronic neutrophilic airway inflammation and increased levels of neutrophil elastase (NE) in the airways.	23316069
Inflammation	Altered Intercellular Communication	Importantly, senescent cells can be proinflammatory and would perpetuate CF chronic inflammation.	23316069
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Inflammation may have a pathogenic role in the progression of nonalcoholic fatty liver disease (NAFLD); by contrast, the role of anti-inflammatory molecules has not been addressed.	23316084
Calcification of mitral valve, Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	Valve calcification and inflammation play key roles in the development of aortic stenosis (AS).	23316316
Idiopathic Inflammatory Myopathies, Granulomatous peritonitis	Altered Intercellular Communication	Granulomatous peritonitis may indicate a number of infectious, malignant, and idiopathic inflammatory conditions.	23318079
Lichen Planus, Inflammation, Leukoplakia	Altered Intercellular Communication	Remaining cases were leukoplakia (n = 28), lichen planus (n = 15) and local inflammation (n = 8).	23318121
Inflammation, Traumatic injury	Altered Intercellular Communication	As this defect will make it vulnerable to injury, inflammation, and destruction by acidic and weakly acidic refluxates, it may in part explain incidences of recurrence of BE following ablation.	23318477
Inflammation	Altered Intercellular Communication	Active surveillance: does serial prostate biopsy increase histological inflammation?	23318528
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Unpaired t-test and kh(2)-square analysis assessed variance in degree of inflammation and location of inflammation relative to cancer grade progression defined as Gleason sum increase.	23318528
Inflammation	Altered Intercellular Communication	A small, statistically significant increase in maximum chronic inflammation (CI) scores with greater number of repeat biopsies was observed.	23318528
Inflammation, Prostate carcinoma	Altered Intercellular Communication	In this pilot study of 56 men on AS for localized prostate cancer, degree of chronic histological inflammation increased with greater number of prostate biopsies, but was not associated with subsequent risk of grade progression.	23318528
Muscle damage, Actual blood loss, Acute inflammation	Altered Intercellular Communication	The use of a tourniquet during total knee arthroplasty was effective for reducing blood loss and avoiding excessive postoperative inflammation and muscle damage.	23318610
Inflammation, Liver Dysfunction	Altered Intercellular Communication	A total of 49 patients with unexplained liver dysfunction and undetermined inflammation were examined.	23318849
Inflammation, Klatskin Tumor	Altered Intercellular Communication	Resection for hilar cholangiocarcinoma: analysis of prognostic factors and the impact of systemic inflammation on long-term outcome.	23319395
Airway structure, ARCN1 gene, Asthma	Altered Intercellular Communication	In the subphenotype analysis, the differential expression of cytokines was more significant between eosinophilic and noneosinophilic airway inflammation than between asthma and COPD, according to both the ELISA and antibody array.	23321180
ARCN1 gene, Asthma, Airway structure	Altered Intercellular Communication	Differential expression of inflammatory mediators is present between patients with COPD or asthma, and eosinophilic or noneosinophilic airway inflammation, and contributes to understanding the cytokine network of airway inflammation.	23321180
Inflammation, Cirrhotic	Altered Intercellular Communication	Lipopolysaccharide (LPS)-expressing bacteria cause severe inflammation in cirrhotic patients.	23321315
Inflammation, Obesity	Altered Intercellular Communication	More research is essential to elucidate resistin's ontological role in the association between obesity, representing a chronic low-grade subclinical inflammation, and PBC.	23321342
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Platelet activation and inflammation are the related mechanisms of pathogenesis in obstructive sleep apnea syndrome (OSAS).	23322273
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	C-reactive protein (CRP) and red cell distribution width (RDW) in relation to the inflammation in OSAS might be increased.	23322273
Autoimmune Diseases, Portal inflammation, Primary Biliary Cholangitis	Altered Intercellular Communication	Primary biliary cirrhosis (PBC) is a slowly progressing autoimmune disease of the liver that is characterized by portal inflammation and immune-mediated destruction of the intrahepatic bile ducts.	23323253
Airway structure, Asthma, Depression, CTCAE	Altered Intercellular Communication	Airway inflammation and hypothalamic-pituitary-adrenal axis activity in asthmatic adults with depression.	23323569
Airway structure, Asthma, Depression, CTCAE	Altered Intercellular Communication	To investigate the features of airway inflammation and hypothalamic-pituitary-adrenal axis (HPAA) activity in patients with asthma accompanied by depression.	23323569
Inflammation, Disease, Atherosclerosis	Altered Intercellular Communication	Leukotriene-based inflammation has been demonstrated to play a crucial role in atherosclerosis, a major risk factor for several human diseases.	23324273
Inflammation, Hematoma, Malignant Neoplasms	Altered Intercellular Communication	The FDG-PET findings of chronic expanding hematomas, including FDG uptake in the peripheral rim of the mass as a result of inflammation, should be recognized as a potential interpretive pitfall that mimics a malignant tumor.	23324446
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Based on the recent studies that highlight the involvement of inflammation in the development of hypertension, we hypothesize that changes in DNA methylation of leukocytes are involved in the pathogenesis of hypertension.	23325143
Fibrosis, Liver, Inflammation, Hepatitis B, Chronic	Altered Intercellular Communication	Can mean platelet volume determine the severity of liver fibrosis or inflammation in patients with chronic hepatitis B?	23325286
Fibrosis, Liver, Inflammation	Altered Intercellular Communication	We aimed to determine whether mean platelet volume (MPV) is one of the variables that determine the severity of liver fibrosis and inflammation.	23325286
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The independent variables determining the severity of liver fibrosis and inflammation were investigated.	23325286
Hepatitis	Altered Intercellular Communication	The independent variables determining the severity of liver inflammation were serum HBV DNA, g-glutamyl transferase, and globulin levels and the MPV [odds ratio and P values were, respectively, 0.1001 and 0.046 for HBV DNA (x10); 1.016 and 0.004 for g-glutamyl transferase; 2.247 and 0.039 for globulin; and 1.488 and 0.004 for the MPV].	23325286
Hepatitis	Altered Intercellular Communication	The sensitivity, specificity, and positive predictive value and negative predictive value of the model predicting the severity of liver inflammation were 60.5, 83, 40.3, and 91.7%, respectively (area under the receiver-operating characteristic curve=0.775, P=0.0001).	23325286
Hepatitis	Altered Intercellular Communication	MPV may provide useful information to predict the degree of liver inflammation along with other markers.	23325286
glycation, Carcinogenesis, Injury of liver, Inflammation	Altered Intercellular Communication	Binding of advanced glycation end products (AGEs) to their receptor (RAGE) increases oxidative stress and inflammation and may be involved in liver injury and subsequent carcinogenesis.	23325627
helium, Liver Cirrhosis	Altered Intercellular Communication	Interestingly, many genes counteracting pro-inflammatory signaling and inflammatory cytokine expression were up-regulated in the cerebral cortex of patients with liver cirrhosis and HE.	23325665
Inflammation	Altered Intercellular Communication	The initial injury is characteristically acute inflammation of gastric mucosa.	23326152
Inflammation, Prehypertension	Altered Intercellular Communication	Whey protein lycosome formulation improves vascular functions and plasma lipids with reduction of markers of inflammation and oxidative stress in prehypertension.	23326213
Inflammation, Ischemic stroke, Cerebrovascular accident	Altered Intercellular Communication	The high levels of MMP-9 in acute ischemic stroke document the involvement of this enzyme in the regulation of inflammation in stroke.	23326959
Ischemia, Inflammation, Carcinoma of lung, Neoplasms	Altered Intercellular Communication	Because the increase in lucigenin concentration, which is due to tissue ischemia, is higher than the increase in luminol, which is directly related to the presence and severity of inflammation, ischemia may be more important than inflammation for tumor development in patients with lung cancer.	23327412
Inflammation, Rosacea, Abnormality of the vasculature	Altered Intercellular Communication	Rosacea has a number of pathophysiological components, chief of which are vascular abnormalities and inflammation.	23328356
Inflammation	Altered Intercellular Communication	Inflammation is consistently present, even in the early forms, strongly suggesting a dual inflammatory and vascular mechanism.	23328356
Inflammation, Diabetic Angiopathies	Altered Intercellular Communication	Biomarkers of inflammation and angiogenesis may detect the progression of diabetic vascular disease and may lead towards earlier interventions that would prevent systemic complications.	23328414
ARCN1 gene, Inflammation	Altered Intercellular Communication	PGE2 is a critical component of an amplifying and self-perpetuating circle inducing senescence and inflammation in COPD fibroblasts.	23328527
ARCN1 gene, Inflammation	Altered Intercellular Communication	Modulating the described PGE2 signaling pathway could provide a new basis to dampen senescence and senescence-associated inflammation in COPD.	23328527
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Inflammation is an important cause of tumorigenesis in various types of malignancy.	23328608
Carcinogenesis, Prostate carcinoma	Altered Intercellular Communication	Inflammation of the prostate may act on prostate carcinomas; particularly that involving M2 macrophage infiltration may play a significant role in prostate carcinogenesis.	23328608
Crohn Disease, Inflammation	Altered Intercellular Communication	Mucosal addressin cell-adhesion molecule (MAdCAM)-1, which is overexpressed on gut endothelium in active Crohn's disease (CD), promotes intestinal recruitment of integrin a(4)b(7)(*) T cells that sustain chronic inflammation.	23328772
Inflammation	Altered Intercellular Communication	Postoperative healing was rapid with no unexpected inflammation, and no palpable bony defects were appreciated in the reconstructed cases.	23328785
Inflammation	Altered Intercellular Communication	IL-17/Th17 mediated synovial inflammation is IL-22 independent.	23328939
Inflammation	Altered Intercellular Communication	Interleukin (IL)-17A and Th17 cells are critically involved in T cell-mediated synovial inflammation.	23328939
Inflammation	Altered Intercellular Communication	However, it remains unclear whether IL-22 and Th22 cells contribute to T cell-mediated synovial inflammation.	23328939
Inflammation, Arthritis	Altered Intercellular Communication	Therefore, we examined the potential of IL-22 and Th22 cells to induce synovial inflammation and whether IL-22 is required for T cell-mediated experimental arthritis.	23328939
Inflammation, Arthritis	Altered Intercellular Communication	The in vivo IL-22 contribution to synovial inflammation was investigated by inducing T cell-mediated arthritis in IL-22 deficient mice and wild-type mice.	23328939
Inflammation, Arthritis	Altered Intercellular Communication	In line with this, similar synovial inflammation and disease severity was found between IL-22 deficient and wild-type mice in T cell-mediated experimental arthritis.	23328939
Inflammation	Altered Intercellular Communication	These findings show that IL-17A/Th17 cell-mediated synovial inflammation is independent of IL-22 and Th22 cells.	23328939
Pain Distress Question, Inflammation	Altered Intercellular Communication	Graft nephrectomy should be indicated in case of graft-related pain or a chronic inflammation syndrome.	23328966
Inflammation	Altered Intercellular Communication	The stroma is often edematous or has a granulation tissue-like appearance with acute or chronic inflammation.	23328975
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Calprotectin is potentially a more sensitive biomarker of disease activity in rheumatoid arthritis (RA) than conventional acute-phase proteins such as the erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) because it directly reflects inflammation in the synovium and synovial fluid rather than systemic inflammatory activity.	23329363
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Our aim is to investigate how the chronic intraprostatic inflammation affect the course of the BPH (benign prostatic hyperplasia).	23329532
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	Between the dates of 2007-2011, the files of the patients who had TUR-P (transurethral resection of the prostate) and underwent open surgery were retrospectively reviewed because of BPH, and the patients were divided into two groups who were operated due to AUR (acute urinary retention) or LUTS (lower urinary tract symptoms) and the clinical data and pathology results of the two groups were compared in terms of chronic intraprostatic inflammation.	23329532
Inflammation	Altered Intercellular Communication	While there was chronic inflammation in 59 of the 130 patients, there was not in 71.	23329532
Inflammation	Altered Intercellular Communication	The risk of acute urinary retention is more frequent in patients with chronic inflammation than in those who lack.	23329532
Inflammation, Dental Plaque	Altered Intercellular Communication	In the margin and centre of the plaque the ratio appears skewed towards effector cells associated with inflammation.	23330679
Inflammation, Watery	Altered Intercellular Communication	Preceding symptoms of a watery eye with mucous discharge and a history or signs of inflammation are typical.	23330705
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	While the chronic inflammation related to autoimmune diseases is known to be associated with an increased cardiovascular risk, much less is known about cerebrovascular risks.	23330740
Coughing, Inflammation	Altered Intercellular Communication	Chronic cough related to eosinophilic inflammation has become an important cause of cough in recent years.	23331776
Inflammation	Altered Intercellular Communication	The clinical presentation of Amyand's hernia varies, depending on the extent of inflammation involved in the hernial sac and the presence or absence of a scrotal abscess.	23331784
Pain Distress Question, Temporal Arteritis, Ischemia	Altered Intercellular Communication	The reason for the gradual pain relief after SGB is unclear, but we believe it was effective for ischemia in temporal arteritis because it led to dilation of affected arteries or suppression of inflammation/edema of the vascular wall.	23332006
Inflammation, Carotid Artery Diseases	Altered Intercellular Communication	Markers of inflammation and CD8 T-cell activation, but not monocyte activation, are associated with subclinical carotid artery disease in HIV-infected individuals.	23332012
Inflammation	Altered Intercellular Communication	All subjects were adults on stable ART with evidence of heightened T-cell activation (CD8(+)CD38(+)HLA-DR(+) >= 19%) or increased inflammation (high-sensitivity C-reactive protein >= 2 mg/L).	23332012
Inflammation, Vascular Diseases	Altered Intercellular Communication	Participants in SATURN-HIV have a high level of inflammation and immune activation that is associated with subclinical vascular disease despite low serum LDL cholesterol.	23332012
Genus Pneumocystis, Airway structure	Altered Intercellular Communication	Pneumocystis colonization has been associated with airway inflammation and obstruction.	23333101
Diabetes, Autoimmune, Insulitis, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	NIT-hAAT has immunomodulatory properties, which delay the onset of autoimmune diabetes, reduce diabetes incidence, inhibit insulitis and b-cell apoptosis, and dampen transplant site inflammation.	23333354
Vasculitis	Altered Intercellular Communication	FDG-PET imaging could be more effective than CT-scan or magnetic resonance imaging in detecting the earliest stages of vascular wall inflammation.	23333520
Restless Legs Syndrome	Altered Intercellular Communication	Restless Legs Syndrome (RLS) is associated with impaired central dopaminergic neurotransmission.	23333538
Inflammation, Autonomic nervous system disorders	Altered Intercellular Communication	Increased body fat, autonomic dysfunction and low-grade chronic inflammation are interrelated risk factors implicated in the etiology of several chronic conditions normally presented by older adults.	23333772
Inflammation, Obesity	Altered Intercellular Communication	We previously demonstrated that angiopoietin-like protein 2 (Angptl2), a pro-inflammatory factor secreted by adipose tissue, promotes adipose tissue inflammation and subsequent systemic insulin resistance in obesity.	23333801
vascular inflammations, Intimal proliferation, Vascular System Injuries	Altered Intercellular Communication	Conversely, vascular inflammation and neointimal hyperplasia after endovascular injury were significantly attenuated in wild-type mice transplanted with Angptl2(-/-) mouse-derived perivascular adipose tissue compared to wild-type mice transplanted with wild-type tissue.	23333801
Communicable Diseases, Inflammation	Altered Intercellular Communication	FDG-PET/CT is useful for confirming the presence of graft infection by detecting high uptake around grafts and excluding other causes of inflammation.	23333838
Colitis	Altered Intercellular Communication	Incidental detection of colonic inflammation on PET/CT using 18F-FDG-labeled autologous leukocytes.	23334139
Inflammation, pseudomembranous colitis	Altered Intercellular Communication	While the pancreas showed no abnormal tracer uptake, colonic inflammation was incidentally detected, and a diagnosis of pseudomembranous colitis was subsequently confirmed on colonoscopy and biopsy.	23334139
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	It is also important to recognize that concurrent conditions requiring treatment with topical medications, such as glaucoma, may be complicated after treatment because of the inflammation and ocular surface irritation after RT.	23334313
Inflammation, Swelling, Edema	Altered Intercellular Communication	Histology commonly shows capillary proliferation, swelling of endothelial cells, perivascular edema, and chronic inflammation with sparse lymphocytic infiltrate.	23334520
Inflammation, Serous retinal detachment	Altered Intercellular Communication	We reviewed the literature and discuss the possibility that laser-induced inflammation could rouse an inflammatory cascade mediated by proinflammatory cytokines and PAI-1, leading to the exacerbation of retinal serous detachment in susceptible patients.	23335311
Inflammation, Intraocular inflammation, Tubulointerstitial nephritis and uveitis, Uveitis, Nephritis, Interstitial	Altered Intercellular Communication	Tubulointerstitial nephritis and uveitis (TINU) syndrome usually shows anterior segment intraocular inflammation, but severe posterior segment intraocular inflammation is rarely observed.	23335312
Inflammation, Macular subretinal hemorrhage	Altered Intercellular Communication	The girl showed development of CNV with subretinal macular hemorrhage along with the exacerbation of anterior chamber inflammation in her left eye.	23335312
Inflammation, Subretinal hemorrhage	Altered Intercellular Communication	The boy showed subretinal hemorrhage from CNV with severe anterior chamber inflammation in his left eye.	23335312
Inflammation, Fibrosis Assessment, Subretinal hemorrhage	Altered Intercellular Communication	With oral prednisolone, anterior chamber inflammation and subretinal hemorrhage disappeared, but shrunken subretinal fibrosis in the macula remained.	23335312
Inflammation, Observation Method - Coagulation, Hepatitis	Altered Intercellular Communication	Biomarkers of inflammation and coagulation are associated with mortality and hepatitis flares in persons coinfected with HIV and hepatitis viruses.	23335804
Cessation of life, Inflammation, Observation Method - Coagulation, Hepatitis	Altered Intercellular Communication	Among HIV-positive patients coinfected with HBV and/or HCV who are initiating ART, biomarkers of inflammation and coagulation are associated with an increased risk of death, whereas HBV coinfection and higher pre-ART interleukin 10 levels are associated with hepatitis flares.	23335804
Genus Fusobacterium, Adenoma, Colonic mucous membrane, Inflammation	Altered Intercellular Communication	These results support a link between the abundance of Fusobacterium in colonic mucosa and adenomas and suggest a possible role for mucosal inflammation in this process.	23335968
Sepsis, Inflammation, Multiple Organ Failure, Bacterial Infections	Altered Intercellular Communication	Levels of APRIL were further elevated in sepsis and significantly correlated with classical markers of inflammation, bacterial infection, or multiorgan failure.	23337484
nervous system disorder, Inflammation, Nerve Degeneration	Altered Intercellular Communication	Multiple sclerosis is a neurological disorder that presents with symptoms including inflammation, neurodegeneration, and demyelination of the central nervous system (CNS).	23339019
Inflammation, Depression, CTCAE, Liver Cirrhosis	Altered Intercellular Communication	Because AST is an important mediator of inflammatory process, further research is needed to delineate the role of inflammation in the cirrhosis comorbid with depression.	23339829
Inflammation, Fluid overload, Chronic Kidney Diseases	Altered Intercellular Communication	Accumulating evidence suggests an association between body volume overload and inflammation in chronic kidney diseases.	23340794
methyldopa, Inflammation	Altered Intercellular Communication	It is well established that oxidative stress, inflammation, and apoptosis play critical roles in pathogenesis of AMD.	23341606
methyldopa, Inflammation	Altered Intercellular Communication	Here we show that mice lacking c-Jun N-terminal kinase 1 (JNK1) exhibit decreased inflammation, reduced CNV, lower levels of choroidal VEGF, and impaired choroidal macrophage recruitment in a murine model of wet AMD (laser-induced CNV).	23341606
methyldopa, Inflammation	Altered Intercellular Communication	These results suggest that JNK1 plays a key role in linking oxidative stress, inflammation, macrophage recruitment apoptosis, and VEGF production in wet AMD and pharmacological JNK inhibition offers a unique and alternative avenue for prevention and treatment of AMD.	23341606
Malignant neoplasm of penis, human papillomavirus, Chronic inflammation, Phimosis	Altered Intercellular Communication	Penile cancer is associated with a number of established risk factors and associated diseases including phimosis with chronic inflammation, human papillomavirus (HPV) infection, poor hygiene and smoking.	23341933
Eosinophilic disorder, Granulomatous inflammation, Meningitis	Altered Intercellular Communication	Previously unreported AEs like drug rash with eosinophilia and systemic symptoms (DRESS), granulomatous inflammation of the central nervous system, and aseptic meningitis, were documented.	23341990
Inflammation, Osage language, Cardiovascular Diseases, Renal function, Sleep Apnea, Obstructive	Altered Intercellular Communication	Both obstructive sleep apnea (OSA) and a novel lipocalin, neutrophil gelatinase associated lipocalin (Ngal), have been reported to be closely linked with cardiovascular disease and loss of kidney function through chronic inflammation.	23342100
Inflammation, Mammary Neoplasms	Altered Intercellular Communication	These findings link telomere content in breast tumors to the expression of several telomere-associated proteins previously shown to be negative regulators of telomere length in cell lines and suggest a link between the expressions of the telomere-associated proteins and mediators of stress and inflammation.	23342266
Inflammation	Altered Intercellular Communication	The lingual cervical coverage did not precipitate the accumulation of anaerobic microorganisms, although it could potentially induce gingival inflammation.	23342333
Inflammation, Dermatitis	Altered Intercellular Communication	We hypothesized that heterozygous FLG mutation carriers who suffer from dermatitis will have strongly reduced or even absent filaggrin levels during episodes of inflammation, potentially increasing the penetration of contact allergens, and hence the risk of becoming sensitized.	23343419
Granulomatous inflammation	Altered Intercellular Communication	Chalazion is a subacute granulomatous inflammation of the eyelid caused by retention of tarsal gland secretions and it's the most common inflammatory lesion of the eyelid.	23343591
Inflammation, Anemia	Altered Intercellular Communication	Inflammation was present in 48.0% of children and 20.8% of women and anemia was diagnosed in 57.6% of children and 38.8% of women.	23343673
Inflammation, Intradermal Route of Drug Administration	Altered Intercellular Communication	Research is needed to clarify the relationships between iron status indicators, particularly in the presence of inflammation, to harmonize global data on prevalence of ID.	23343673
Fibrinoid necrotizing inflammation	Altered Intercellular Communication	MMP expression in rheumatoid inflammation: the rs11568818 polymorphism is associated with MMP-7 expression at an extra-articular site.	23343931
Fibrinoid necrotizing inflammation	Altered Intercellular Communication	Less is known of the involvement of MMPs at extra-articular sites of rheumatoid inflammation.	23343931
Refractory anemias, Destruction of tissue, Inflammation, Rheumatoid Factor	Altered Intercellular Communication	We assessed the relative contribution from MMP-1, MMP-3, MMP-7 and MMP-12 to joint and extra-articular tissue destruction and inflammation by comparing gene expression in joint synovia and subcutaneous rheumatoid nodules from RA patients.	23343931
Inflammation	Altered Intercellular Communication	The high MMP-7 expression in nodules was associated with the single-nucleotide polymorphism (SNP) rs11568818 (-181A>G, MMP-7 promoter) and more active inflammation within the nodule lesions.	23343931
Fibrinoid necrotizing inflammation	Altered Intercellular Communication	MMP-12 expression reflects the involvement of monocyte/macrophages in rheumatoid inflammation.	23343931
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The aim of the study was to compare the serum levels of GGT (which is considered a novel marker of oxidative stress) between patients with stable chronic obstructive pulmonary disease (COPD) and those with acute exacerbation of COPD, and the relationship of GGT with inflammation.	23344614
Inflammation, Edema	Altered Intercellular Communication	Consequently, a CT scan of her abdomen was performed which showed mucosal oedema and inflammation involving virtually the entire length of her large bowel (the 'accordion sign').	23345475
pseudomembranous colitis	Altered Intercellular Communication	In this case, the radiological appearance of the accordion sign which is traditionally known to be pathognomonic of pseudomembranous colitis, reveals that it may also be indicative of severe colonic luminal inflammation.	23345475
Granulomatous inflammation, Caseous necrosis	Altered Intercellular Communication	In both patients, diagnosis of TB-PE was established by demonstration of granulomatous inflammation, caseous necrosis and positive stain for acid-fast bacilli in pleural biopsy specimens.	23345502
Granulomatous inflammation, Congenital bronchogenic cyst	Altered Intercellular Communication	Pathological examination of the excised lobe showed a bronchogenic cyst combined with a destructive cavitary lesion with granulomatous inflammation.	23346002
Inflammation, Biliary calculi	Altered Intercellular Communication	Single-incision laparoscopic cholecystectomy (SILC) has been performed in patients with gallbladder stones without inflammation.	23347708
Inflammation, Specimen Type - Fistula, Fasciitis, septic	Altered Intercellular Communication	In 26 patients the diagnosis was a septic condition: abscess (12 patients), fistula (4), inflammation (9) and necrotizing fasciitis (1).	23347777
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	The protein C (PC) system is an important regulator of both coagulation and inflammation.	23348224
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	The NLRP1 gene product is implicated in inflammation, autoimmune disorders, and caspase mediated apoptosis.	23349227
vascular inflammations	Altered Intercellular Communication	While angiopoietin (Ang)-1 protects from vascular inflammation and leakage, Ang-2 disrupts endothelial barrier function.	23349297
Inflammation, Chronic Lymphocytic Leukemia	Altered Intercellular Communication	The monocytic population in chronic lymphocytic leukemia shows altered composition and deregulation of genes involved in phagocytosis and inflammation.	23349302
Inflammation, Chronic Lymphocytic Leukemia	Altered Intercellular Communication	In conclusion, altered composition and deregulation of genes involved in phagocytosis and inflammation were found in blood monocytes obtained from chronic lymphocytic leukemia patients, suggesting that leukemia-mediated "education" of immune elements may also include the establishment of a skewed phenotype in the monocyte/macrophage population.	23349302
Inflammation, Asthma	Altered Intercellular Communication	Airway and systemic inflammation in obese children with asthma.	23349447
Inflammation, Asthma	Altered Intercellular Communication	Obese asthma presents via altered airway and systemic inflammation in adults.	23349447
Inflammation, Asthma, Obesity	Altered Intercellular Communication	Obesity was not associated with significantly altered airway or systemic inflammation in asthmatic children.	23349447
Inflammation, Obesity	Altered Intercellular Communication	Low-grade inflammation in obesity is associated with accumulation of the macrophage-derived cytokine osteopontin (OPN) in adipose tissue and induction of local as well as systemic insulin resistance.	23349498
vascular inflammations	Altered Intercellular Communication	A clinical evaluation of statin pleiotropy: statins selectively and dose-dependently reduce vascular inflammation.	23349755
vascular inflammations	Altered Intercellular Communication	Statins are thought to reduce vascular inflammation through lipid independent mechanisms.	23349755
Malaria, Falciparum, Inflammation	Altered Intercellular Communication	Since UA is associated with endothelial inflammation in non-malaria diseases, we hypothesized that elevated UA levels contribute to the endothelial pathology of P. falciparum malaria.	23349902
Airway structure, Asthma	Altered Intercellular Communication	Fractional exhaled nitric oxide (FENO), a non-invasive marker of eosinophilic airway inflammation, is increasingly used for diagnostic and therapeutic decisions in adult and paediatric asthma.	23349918
Crohn Disease, Inflammation	Altered Intercellular Communication	Crohn's Disease (CD)-associated inflammation is supposed to be driven by T helper (Th)1/Th17 cell-derived cytokines, even though there is evidence that the mucosal profile of cytokine may vary with the evolution of the disease.	23349929
Granulomatous inflammation, Mycobacterium Infections, Caseous necrosis, Malignant Neoplasms	Altered Intercellular Communication	Biopsy of the axillar lymph node was performed because of suspected malignancy, and the results showed that the lymph node had granulomatous inflammation with caseous necrosis and Langhans giant cells, suggestive of mycobacterial infection.	23350517
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Evidence indicates that liver fibrosis contains uncontrolled inflammation as a part of its etiology.	23350952
Inflammation, Albuminuria, Congestive heart failure, Chronic heart failure, Vascular System Injuries	Altered Intercellular Communication	Albuminuria might be a marker of the various pathophysiologic changes, such as diffuse vascular injury and systemic inflammation, that arise in patients with chronic heart failure (CHF).	23351461
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Inflammation in young adulthood is associated with myocardial infarction later in life.	23351818
Inflammation	Altered Intercellular Communication	During Swedish national conscription tests from 1969 through 1978, the erythrocyte sedimentation rate, as a measure of inflammation, was measured in 433,577 young Swedish men.	23351818
Inflammation, Extraocular rectus muscle, Muscle of orbit, Thyroid associated opthalmopathies	Altered Intercellular Communication	In the treatment of Graves' ophthalmopathy, rectus muscle resections generally are avoided because of the concern of reaggravating inflammation and creating excessive extraocular muscle restriction.	23352720
Inflammation	Altered Intercellular Communication	Moreover, we report the novel finding that IRS1 variant G972R (rs1801278) may contribute to oxidative DNA damage and inflammation.	23353623
Degenerative polyarthritis, Pain Distress Question, Inflammation	Altered Intercellular Communication	This study shows the efficacy of an AGE inhibitor on decreasing pain and inflammation, and increasing daily activity and mobility in OA patients.	23354008
Inflammation, Lung Diseases, Interstitial, Vasculitis, CTCAE	Altered Intercellular Communication	Histological examination demonstrated the presence of an obliterative vasculitis with interstitial pulmonary perivascular inflammation.	23354025
Data types - Address	Altered Intercellular Communication	Because several evidences show that patients might display quite different concentrations of neurotransmitters in brain areas, assessing metabolites in different and well-characterized AD stages should be investigated further.	23354600
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Although the etiology of MS is still not known, inflammation and autoimmunity are considered to be the central components of this disease.	23354834
Nonalcoholic Steatohepatitis, Steatohepatitis, Inflammation	Altered Intercellular Communication	Presence and severity of hepatic steatosis, lobular inflammation, and hepatocyte ballooning were more common among nonalcoholic steatohepatitis patients (all p < 0.001).	23355033
Inflammation, Atrophic	Altered Intercellular Communication	Histopathological analyses of labial salivary gland biopsies showed deposition of gelsolin amyloid, atrophy and inflammation.	23356404
Inflammation	Altered Intercellular Communication	Despite experimental evidence, clinical demonstration of acute state of oxidative stress and inflammation during post-cardiac arrest syndrome is lacking.	23356570
Inflammation	Altered Intercellular Communication	Plasma level of thioredoxin (TRX), a redox-active protein induced under conditions of oxidative stress and inflammation, is increased in various critical care conditions.	23356570
Cardiac Arrest, Inflammation	Altered Intercellular Communication	Our data show for the first time that TRX levels were elevated early following cardiac arrest, suggestive of oxidative stress and inflammation occurring with this condition.	23356570
Inflammation, Pain Distress Question	Altered Intercellular Communication	Most frequent complication of abutments was periodontal pocket formation (52%), followed by the inflammation (29%), increase in mobility (27%) and pain (4%).	23356632
Inflammation, Tissue injury	Altered Intercellular Communication	in cases with scarring or inflammation induced by tissue injury.	23356949
Schizophrenia	Altered Intercellular Communication	Alterations in glutamate transporter expression may lead to abnormal glutamate neurotransmission contributing to the pathophysiology of schizophrenia.	23356950
Inflammation, Neoplasms	Altered Intercellular Communication	Nonmalignant conditions, mainly inflammation and some benign tumors, however, can cloud the clinical picture by taking up FDG and producing a false-positive result.	23357820
Airway structure	Altered Intercellular Communication	Estrogen has previously been shown to increase the bioactivation of several compounds in tobacco smoke, which may enhance smoke-induced airway inflammation in fertile women.	23357876
Acute inflammation	Altered Intercellular Communication	The preoperative diagnosis included a high rate of acute biliary tract inflammation (24 of 38, 63.2 %).	23359177
Inflammation, Carcinogenesis, Colorectal Carcinoma	Altered Intercellular Communication	Our study confirmed the hypothesis that inflammation has a major effect on carcinogenesis of CRC.	23359190
Inflammation, physiopathological	Altered Intercellular Communication	However, pretreatment with glycyrrhizin attenuated LPS-induced acute peritoneal inflammation and dysfunction in mice.	23359306
Dermatitis	Altered Intercellular Communication	Keratinocyte overexpression of IL-17C promotes psoriasiform skin inflammation.	23359500
Psoriasis, Dermatitis	Altered Intercellular Communication	These findings identify a role for IL-17C in skin inflammation and suggest a pathogenic function for the elevated IL-17C observed in lesional psoriasis skin.	23359500
Psoriasis	Altered Intercellular Communication	Psoriasis patients treated with etanercept rapidly decrease cutaneous IL-17C levels, suggesting IL-17C/TNF-a-mediated inflammatory signaling is critical for psoriasis pathogenesis.	23359500
Airway Obstruction, Inspiratory stridor	Altered Intercellular Communication	The different types of foreign body impaction in the throat and the inflammatory condition of throat or the inspiratory stridor due to upper airway obstruction were the main emergency situation recorded.	23360039
Inflammation, Pancreatic Ductal Adenocarcinoma	Altered Intercellular Communication	To test whether or not the association between inflammation and pancreatic ductal adenocarcinoma (PC) is facilitated by host susceptibility, specifically by genetic polymorphisms in inflammation-related genes.	23360921
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Effects of high-dose cholecalciferol on serum markers of inflammation and immunity in patients with early chronic kidney disease.	23361158
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We aimed to determine if high-dose cholecalciferol supplementation for 1 year in subjects with early chronic kidney disease (CKD) improved circulating markers of inflammation and immunity.	23361158
Inflammation, Squamous cell carcinoma	Altered Intercellular Communication	A single false-positive case was dense inflammation with squamous cells misinterpreted as squamous cell carcinoma (SCC) on cytology.	23361285
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Osteopontin: participation in inflammation or mucosal protection in inflammatory bowel diseases?	23361573
Inflammation, Colitis	Altered Intercellular Communication	OPN promoted the Th1 immune response and strengthened inflammation in the mouse colitis model.	23361573
Inflammation, Metabolic Diseases	Altered Intercellular Communication	Increased inflammation and oxidative stress are associated with insulin resistance (IR) and metabolic disorders.	23361591
Inflammation, Fibrosis Assessment, Crohn Disease	Altered Intercellular Communication	Detecting active inflammation and fibrosis in pediatric Crohn's disease: prospective evaluation of MR-E and CT-E.	23361877
Crohn Disease, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Symptoms of Crohn's disease (CD) can be due to active inflammation or fibrosis.	23361877
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The purpose of our study was to compare the ability of MR-E and CT-E to assess for active inflammation and mural fibrosis in patients with known CD as compared to a histologic reference standard.	23361877
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	These were evaluated by the pathologist for active inflammation and fibrosis.	23361877
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We found that while CT-E and MR-E were similar in their accuracies of depicting active inflammation, MR-E was significantly more sensitive in detecting fibrosis.	23361877
Fibrous, Inflammation, Dental Plaque, Calcinosis	Altered Intercellular Communication	Compared with plaques from patients with ocular events only, those from patients with cerebral events had significantly more large lipid core (odds ratio [OR], 1.38; 95% confidence interval [CI], 1.05-1.82; P=0.02), inflammation (OR, 1.32; 95% CI, 1.02-1.72; P=0.04) and overall plaque instability (OR, 1.37; 95% CI, 1.05-1.80; P=0.02), and less fibrous content (OR, 0.71; 95% CI, 0.54-0.92; P=0.01), and calcification (OR, 0.70; 95% CI, 0.54-0.91; P=0.008).	23362077
Inflammation	Altered Intercellular Communication	PRC also orchestrates a robust response to metabolic stress by promoting the expression of multiple genes specifying inflammation, proliferation, and metabolic reprogramming.	23364789
Sepsis	Altered Intercellular Communication	Sepsis is an excessive inflammatory condition with a high mortality rate and limited prediction and therapeutic options.	23365080
Inflammation, White matter degeneration, Traumatic	Altered Intercellular Communication	Inflammation and white matter degeneration persist for years after a single traumatic brain injury.	23365092
Inflammation, White matter degeneration, Traumatic	Altered Intercellular Communication	These data present striking evidence of persistent inflammation and ongoing white matter degeneration for many years after just a single traumatic brain injury in humans.	23365092
Inflammation, White matter degeneration	Altered Intercellular Communication	Future studies to determine whether inflammation occurs in response to or, conversely, promotes white matter degeneration will be important.	23365092
Inflammation, Spondylitis, Rheumatism	Altered Intercellular Communication	Inflammation driven connective tissue turnover is key in rheumatic diseases, such as ankylosing spondylitis (AS).	23365672
Inflammation	Altered Intercellular Communication	Type II collagen is the primary structural protein of cartilage and type III collagen of connective tissues, and obvious targets for the collagenalytic, which increase during tissue inflammation.	23365672
Inflammation, Irritation	Altered Intercellular Communication	Although orthopedic implants are known to cause irritation and inflammation, to our knowledge, this is the first case report to describe a patient with rice bodies secondary to an orthopedic implant.	23365810
Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	Acute Respiratory Distress Syndrome (ARDS) is characterized by inflammation, filling of the lung with fluid and the collapse of lung units.	23368982
Inflammation, Structure of parenchyma of lung	Altered Intercellular Communication	WNT signalling is activated during lung tissue damage and inflammation.	23370438
Airway structure, ARCN1 gene	Altered Intercellular Communication	As WNT-4 further increases CSE-induced pro-inflammatory cytokine release in bronchial epithelium, we propose that higher epithelial WNT-4 levels in combination with cigarette smoking may have important implications for the development of airway inflammation in COPD.	23370438
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	Chronic sub-acute inflammation contributes to the pathogenesis of type 2 diabetes mellitus and cardiovascular disease.	23370525
Inflammation	Altered Intercellular Communication	It resolved in five patients with well-controlled inflammation, but was progressive in all of the other patients.	23371008
Inflammation, Tissue injury	Altered Intercellular Communication	This is possibly due to the activation of cytoprotective pathways resulting in limitation of the tissue injury secondary to inflammation.	23371318
Inflammation	Altered Intercellular Communication	Because CXCL2 could represent a WAT-produced chemokine, we explored its role in obesity-associated inflammation.	23372021
Inflammation, Obesity	Altered Intercellular Communication	Activated neutrophils in obesity may influence vis WAT-ECs functions and contribute to WAT inflammation.	23372021
Inflammation, "Huntingtons Disease Pathway	Altered Intercellular Communication	A critical role of astrocyte-mediated nuclear factor-kB-dependent inflammation in Huntington's disease.	23372043
HD Term Type, Inflammation	Altered Intercellular Communication	Thus, HD glia might play an important role in chronic inflammation that accelerates disease progression in HD mice.	23372043
HD Term Type, Neurogenic Inflammation	Altered Intercellular Communication	Therapeutic interventions aimed at preventing neuronal inflammation may be an important strategy for treating HD.	23372043
Inflammation, Bacterial Infections	Altered Intercellular Communication	Down-regulation of miR-150 was recently linked to inflammation and bacterial infection.	23372743
Crohn Disease	Altered Intercellular Communication	Suppression of Crohn's disease inflammation potentially leads to the control of amyloid A production, assessed by a decrease of serum amyloid A. Kidney transplantation provides a long survival.	23373823
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Stump appendicitis is a rare disease characterized by inflammation of the appendiceal remnant.	23374389
Inflammation, Liver carcinoma	Altered Intercellular Communication	The Glasgow Prognostic Score, an inflammation based prognostic score, predicts survival in patients with hepatocellular carcinoma.	23374755
Inflammation, Elastosis perforans serpiginosa	Altered Intercellular Communication	The degree of inflammation in the EPS specimens progressively increased with age, education, and body mass index (P <.001 for trend for all).	23374811
vascular inflammations	Altered Intercellular Communication	Statins are frequently administered to reduce low-density lipoprotein cholesterol (LDL-C) and vascular inflammation, because LDL-C and high sensitive C-reactive protein (hs-CRP) are associated with high risk for cardiovascular events.	23374898
Inflammation, Pseudomembrane	Altered Intercellular Communication	Colonoscopy showed diffuse inflammation in the entire large bowel and pseudomembranes in the sigmoid colon.	23375026
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Chronic Kidney Diseases, Obesity	Altered Intercellular Communication	Chronic low-grade inflammation and/or obesity are suggested to induce chronic kidney disease (CKD) in patients with type 2 diabetes.	23375231
Inflammation, Tropical Spastic Paraparesis	Altered Intercellular Communication	HTLV-1-associated inflammatory myopathies: low proviral load and moderate inflammation in 13 patients from West Indies and West Africa.	23375238
Tissue damage, Inflammation	Altered Intercellular Communication	Muscle biopsies were used for a broad immunohistological evaluation of tissue damage and inflammation, as well as identification of infected cells through in situ hybridization.	23375238
Inflammation, Idiopathic eosinophilic myositis	Altered Intercellular Communication	Histological alterations and inflammation in patients muscles were mostly moderate, with classical features of idiopathic myositis and rare HTLV-1-infected infiltrating cells.	23375238
Myositis	Altered Intercellular Communication	We show here that muscle inflammation is moderate in HAIM, and accompanied by a low HTLV-1 proviral load, suggesting that the pathogenetic events do not exactly mirror those of other HTLV-1-associated inflammatory diseases.	23375238
Communicable Diseases, Inflammation	Altered Intercellular Communication	Lipocalin-2 (LCN-2), which is expressed in immunocytes as well as hepatocytes, is upregulated in cells under stress from infection or inflammation with increase in serum levels.	23375308
Inflammation, Hypoxia, Anemia, hepcidin	Altered Intercellular Communication	Hepcidin, produced by hepatocytes in response to anemia, hypoxia, or inflammation, is a key regulator of iron homeostasis.	23375326
Inflammation, Anemia, Chronic disease	Altered Intercellular Communication	This form of anemia in mTOR-treated OHT resembles the disorder of chronic disease, suggesting that OHT patients show low-grade inflammation, which should be investigated for underlying, potentially reversible causes.	23375326
Inflammation, Hypoxia, Anemia, hepcidin	Altered Intercellular Communication	Hepcidin is a small defensin-like peptide whose production by hepatocytes is modulated in response to anemia, hypoxia, or inflammation.	23375327
Inflammation, Corneal Endothelial Cell Loss	Altered Intercellular Communication	Impaired kidney function was strongly associated with endothelial damage and inflammation.	23375328
Granulomatous inflammation, Hyperplasia	Altered Intercellular Communication	Other histopathological features encountered included perieccrine infiltration (n = 5), focal subcutaneous involvement (n = 4), granulomatous inflammation (n = 3), epidermal hyperplasia (n = 2), and 1 each of infiltration of muscle bundles, numerous eosinophils in the infiltrate, and angiocentricity.	23375516
Inflammation, Cystitis, Granulomatous inflammation, Nephrogenic metaplasia, Squamous metaplasia	Altered Intercellular Communication	Of the 85 nonneoplastic cases, prominent morphologic findings included significant chronic inflammation (59), granulomatous inflammation including foreign body giant cell reaction (6), acute inflammation (7), squamous metaplasia (9), cystitis glandularis (10), and nephrogenic metaplasia (2).	23375647
Inflammation, Complications of Diabetes Mellitus	Altered Intercellular Communication	Advanced glycation end-products (AGEs) play a pivotal role in the development of diabetic complications by inducing inflammation.	23376161
Intraocular inflammation	Altered Intercellular Communication	Treatment outcome was ascertained by a composite endpoint comprised of visual acuity, intraocular inflammation, ability to taper immunosuppressives, and posterior segment imaging.	23376607
Intraocular inflammation	Altered Intercellular Communication	Clinical response was defined by improvement in at least one parameter, worsening in none, and well controlled intraocular inflammation.	23376607
Gastrointestinal inflammation	Altered Intercellular Communication	Fecal S100A12 has been reported as a novel marker of intestinal inflammation.	23377171
Tumor necrosis, Inflammation, Pain Distress Question	Altered Intercellular Communication	Despite treatment with a tumor necrosis factor blocking agent, the patient was not pain free and inflammation markers remained elevated.	23377199
Inflammation, Depression, CTCAE, Cerebrovascular accident	Altered Intercellular Communication	Sustained inflammation 1.5 years post-stroke is not associated with depression in elderly stroke survivors.	23378749
Inflammation, Depression, CTCAE, Cerebrovascular accident	Altered Intercellular Communication	Depression is common in elderly stroke survivors and has been associated with systemic inflammation.	23378749
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	We aimed to investigate an elderly population of Swedish stroke patients for evidence of sustained peripheral inflammation 18 months post-stroke and to identify if inflammation is associated with post-stroke depression at 18 months post-stroke.	23378749
Hepatic inflammation	Altered Intercellular Communication	The degree of hepatic inflammation was graded using the histological activity index (HAI).	23379437
Inflammation, Complete atrioventricular block	Altered Intercellular Communication	Peripheral Th17 cell frequency is associated closely with inflammation activity of liver tissues in paediatric patients with CHB.	23379437
Communicable Diseases, Inflammation	Altered Intercellular Communication	Our study shows that catheters might contribute to increased inflammation independent of infection, and support the avoidance of catheters and a timely conversion to fistulas with catheter removal.	23379491
Inflammation, Antigen T Cell Receptor, beta Chain	Altered Intercellular Communication	Hemodialysis (HD) patients are characterized by impaired T-cell function at least in part because of T-cell zeta-chain downregulation due to inflammation.	23379493
Inflammation, Periodontitis, Tooth Loss	Altered Intercellular Communication	Tooth loss and periodontitis by socio-economic status and inflammation in a longitudinal population-based study.	23379538
Inflammation, Periodontitis, Tooth Loss	Altered Intercellular Communication	To examine the associations between factors of socio-economic status (SES), systemic inflammation and the progression of periodontitis and incidence of tooth loss.	23379538
Sepsis, Inflammation	Altered Intercellular Communication	During sepsis, inflammation can be orchestrated by the interaction between circulating and vascular cells that, under activation, release MPs (microparticles).	23379624
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	Association between posttraumatic stress disorder and inflammation: a twin study.	23379997
Post-Traumatic Stress Disorder, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The association of posttraumatic stress disorder (PTSD) with cardiovascular disease risk may be mediated by inflammation.	23379997
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	Our objective was to examine the association between PTSD and measures of inflammation and to determine whether these associations are due to shared familial or genetic factors.	23379997
Cessation of life, Inflammation, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	There have been major advances in the understanding of mechanisms that contribute to nigral dopaminergic cell death, including mitochondrial dysfunction, oxidative stress, altered protein handling, and inflammation.	23380027
Inflammation	Altered Intercellular Communication	We investigated how loss of PTPN22 could contribute to chronic inflammation of the intestine.	23380085
Airway structure	Altered Intercellular Communication	Maternal smoking affects lung function and airway inflammation in young children with multiple-trigger wheeze.	23380219
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The presumed chronic inflammatory etiology of osteoarthritis suggests that nociceptive processes and neurogenic inflammation predominate in this condition.	23380268
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Immune activation and inflammation play significant roles in the pathogenesis of Alzheimer's disease (AD).	23380586
Communicable Diseases, Inflammation, Ear Inflammation	Altered Intercellular Communication	Toll-like receptors are considered to be important factors for clearance of infection and resolution of inflammation in otitis media.	23380629
Communicable Diseases, Inflammation	Altered Intercellular Communication	Although there was no definite infection or inflammation, careful follow-up was considered to be mandatory.	23381366
Orchitis	Altered Intercellular Communication	94% of patients with C-reactive protein values <10 mg/dl showed early stages of appendicular inflammation (p<0,05).	23381749
Hypertensive (finding)	Altered Intercellular Communication	N-terminal rather than full-length osteopontin or its C-terminal fragment is associated with carotid-plaque inflammation in hypertensive patients.	23382482
Inflammation, Hypertensive (finding), atherosclerotic	Altered Intercellular Communication	Hypertensive patients develop carotid atherosclerotic plaques with enhanced inflammation.	23382482
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	We conducted a study to examine whether plaque inflammation in hypertensive patients corresponds to the expression of OPN or of its cleaved forms or both.	23382482
Inflammation	Altered Intercellular Communication	Moderate to heavy staining for OPN characterized 87% of the plaques with high-degree inflammation but only 44% of those with low-degree inflammation, corresponding to the percentages of plaques that were heavily stained for the macrophage marker CD68 (93% versus 26%, respectively, P < 0.01).	23382482
Inflammation	Altered Intercellular Communication	The abundance of MMP-12 was significantly greater in the high- than in the low-degree plaque inflammation group (4.8 (range 1.9-8.8) vs. 1.1 (range 0.3-1.4), respectively; P = 0.03).	23382482
Hypertensive (finding)	Altered Intercellular Communication	The N-terminal fragment of osteopontin, rather than OPN-FL or OPN-C, is associated with carotid plaque inflammation in hypertensive patients.	23382482
CLU protein, human	Altered Intercellular Communication	The results of this study suggest that inflammation-induced BM exhaustion and a disturbed progenitor cell mobilization response due to reduced levels and activity of MMP-9 in the BM and alterations in the SDF-1a/CXCR4 interaction contribute to the attenuated neovascularization in CLI patients.	23383236
Inflammation, Structure of parenchyma of lung	Altered Intercellular Communication	In this progressive disease, chronic inflammation in the lung contributes to lung tissue destruction leading to the formation of chemotactic collagen fragments such as N-acetylated Proline-Glycine-Proline (N-ac-PGP).	23383243
Inflammation, Pulmonary Emphysema, Neutrophil Infiltration	Altered Intercellular Communication	This study indicates that neutrophils activated by cigarette smoke extract can breakdown collagen into N-ac-PGP and that this collagen fragment itself can activate neutrophils, which may lead in vivo to a self-propagating cycle of neutrophil infiltration, chronic inflammation and lung emphysema.	23383243
Pain Distress Question, Inflammation, Communicable Diseases, Swelling, Fracture, Infection of bone	Altered Intercellular Communication	Based on their experience and a review of the literature, the authors suggest that bone infection be considered for patients with closed fractures complicated by excessive or prolonged pain and swelling with evident signs of inflammation where no other obvious infection is apparent.	23383681
Barrett Esophagus, Inflammation	Altered Intercellular Communication	Barrett's esophagus (BE) is considered a complication of the inflammation provoked by acid and bile reflux.	23384184
Angiomyolipoma, Inflammation, Renal Cell Carcinoma Pathway	Altered Intercellular Communication	Pathology revealed angiomyolipoma (3), renal cell carcinoma (2), and chronic inflammation (1).	23384321
Gastrointestinal inflammation	Altered Intercellular Communication	Endoscopy should be decided based on clinical criteria, but also driven by noninvasive tests to assess the digestive absorptive functions and intestinal inflammation.	23384809
Inflammation	Altered Intercellular Communication	Robust shifts in S100a9 expression with aging: a novel mechanism for chronic inflammation.	23386971
Inflammation	Altered Intercellular Communication	These findings offer support for a novel mechanism by which a SPI1/PU.1-S100a9 axis sustains chronic inflammation during aging.	23386971
Inflammation, Infection	Altered Intercellular Communication	They are based on spreading infections from focal sources of inflammation in abdomen or damaged intestinal wall.	23387814
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	In 88,22+-1,67% of cases nodular prostatic hyperplasia was combined with diffuse or focal inflammation, engorgements of prostate gland secretion were observed in 81,76+-2,97%.	23388536
Inflammation	Altered Intercellular Communication	Inflammation is associated with future SBP in the Taiwanese population.	23388833
Hypertensive disease, Inflammation, Dyslipidemias	Altered Intercellular Communication	In summary, these data suggest a complex relationship between inflammation and HTN with dyslipidemia.	23388885
Inflammation	Altered Intercellular Communication	Diagnostic microdialysis can detect local inflammation and may predict the development of CLS early before severe clinical signs appear.	23389476
Hepatic inflammation	Altered Intercellular Communication	Here, we considered both liver fat burden measured by CT (FL) and the non-specific measure of hepatic inflammation -alanine aminotransferase (ALT).	23390892
palladium	Altered Intercellular Communication	Malnutrition-inflammation score predicts long-term mortality in Chinese PD patients.	23391316
palladium, Malnutrition	Altered Intercellular Communication	MIS is a promising marker for malnutrition inflammation assessment and an independent predictor of long-term mortality in Chinese PD patients.	23391316
Inflammation, Calcinosis, Atherosclerosis, Aortic Valve Stenosis	Altered Intercellular Communication	Aortic stenosis, atherosclerosis, and skeletal bone: is there a common link with calcification and inflammation?	23391586
Inflammation, Aortic valve calcification, Atherosclerosis	Altered Intercellular Communication	Using non-invasive imaging, we compared aortic valve calcification and inflammation activity with that measured in atherosclerosis and bone.	23391586
Acute and chronic inflammation	Altered Intercellular Communication	Subsequent increases in biliary leaks might contribute to the pathogenesis of chronic biliary inflammation in these patients.	23391819
Mastitis, Inflammation	Altered Intercellular Communication	Of the 51 cases with non-puerperal mastitis, 94.1% (48/51) were confirmed as having acute or chronic inflammation, and the other 3 had plasma cell mastitis; areola papillaris inflammation was found in 39.2% (20/51) of the cases.	23392197
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Reduction of inflammation should theoretically reduce the development of cancer.	23392347
Hypoalbuminemia	Altered Intercellular Communication	The Glasgow Prognostic Score (GPS), which is an inflammation-based prognostic factor, is defined by the presence of elevated C-reactive protein and hypoalbuminemia.	23392422
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Clusters of comorbidities based on validated objective measurements and systemic inflammation in patients with chronic obstructive pulmonary disease.	23392440
ARCN1 gene, Inflammation	Altered Intercellular Communication	The coexistence of objectively identified comorbidities and the role of low-grade systemic inflammation in the pathophysiology of COPD remain to be elucidated.	23392440
Inflammation	Altered Intercellular Communication	To cluster 13 clinically important objectively identified comorbidities, and to characterize the comorbidity clusters in terms of clinical outcomes and systemic inflammation.	23392440
methyldopa, Inflammation	Altered Intercellular Communication	This information might shed light on underlying pathological mechanisms involving inflammation and could be of clinical utility in the identification of persons at high risk of AMD who may benefit from increased adherence to lifestyle recommendations, eye examination schedules, and therapeutic protocols.	23392454
Inflammation	Altered Intercellular Communication	IL-34 seems to be involved in the pathogenesis of salivary gland inflammation in p-SS.	23392590
Paraneoplastic Syndromes, Osteomalacia, Hypophosphatemia	Altered Intercellular Communication	Oncogenic osteomalacia, a paraneoplastic syndrome associated with hypophosphatemia due to increased urinary phosphate excretion, is caused by excessive synthesis and secretion of fibroblast growth factor 23 (FGF23), a phosphaturic hormone that is normally produced by osteocytes.	23393166
Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Elevated serum uric acid has been associated with a variety of cardiovascular disease and with inflammation, but these have been little explored in chronic kidney disease (CKD).	23394103
HD Term Type, Inflammation, Atherosclerosis	Altered Intercellular Communication	These original data suggest that uric acid may have a role in inflammation and atherosclerosis in HD patients.	23394103
Eosinophilic inflammation	Altered Intercellular Communication	Suppression of mucosal eosinophilic inflammation is one of the pathways by which PLK DS improves pollinosis-induced nasal obstruction.	23394502
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	4D-PET/CT with [(11)C]-PK11195 and [(11)C]-(D)-deprenyl does not identify the chronic inflammation in asymptomatic abdominal aortic aneurysms.	23394769
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	The aim of this study was to investigate the relevance of inflammation in the pathogenesis of abdominal aortic aneurysm (AAA) in vivo with two novel positron emission tomography (PET) tracers: [(11)C]-PK11195 which targets the translocator protein (18 kDa) expressed on macrophages and [(11)C]-d-deprenyl with a yet unknown target receptor expressed in chronic inflammation.	23394769
Inflammation	Altered Intercellular Communication	The chronic inflammation observed in the vessel wall was not detectable with [(11)C]-PK11195 and [(11)C]-d-deprenyl.	23394769
Granulomatous inflammation	Altered Intercellular Communication	B. pseudomallei was isolated from purulent material, and histologic examination revealed granulomatous inflammation.	23395629
Granulomatous inflammation, Melioidosis	Altered Intercellular Communication	The present case highlights the need for an awareness of melioidosis as a new differential diagnosis for a nontuberculous, granulomatous inflammation in those living in or visiting tropical regions.	23395629
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Hepatic insulin resistance is a driving force in the pathogenesis of type 2 diabetes mellitus (T2DM) and is tightly coupled with excessive storage of fat and the ensuing inflammation within the liver.	23396210
Inflammation	Altered Intercellular Communication	Adiposity and fat distribution in relation to inflammation and oxidative stress in a relatively lean population of Chinese women.	23396296
Inflammation, Cirrhotic, Peritoneal Fluid (body substance)	Altered Intercellular Communication	Mean platelet volume is a useful indicator of systemic inflammation in cirrhotic patients with ascitic fluid infection.	23396741
Inflammation, Intestinal Microbiome	Altered Intercellular Communication	Biomarkers of chemotherapy-induced diarrhoea: a clinical study of intestinal microbiome alterations, inflammation and circulating matrix metalloproteinases.	23397098
Inflammation	Altered Intercellular Communication	Patients clinically responding to biologics might still have the potential of moderate/severe local joint inflammation, composed in particular of and possibly driven by the autoinflammatory TLR(+) cells.	23397147
Inflammation, Structure of beta Cell of islet, Diabetes Mellitus, Non-Insulin-Dependent, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	As chronic inflammation and mitochondrial dysfunction are key factors mediating pancreatic beta cell impairment in type 2 diabetes, we investigated the role of SIRT3 in the maintenance of beta cell function and mass in type 2 diabetes.	23397292
Inflammation, Obesity	Altered Intercellular Communication	Increased production of chemokines by adipose tissue and defective adipose tissue oxygenation as a result of obesity may induce leucocyte infiltration and subsequent systemic inflammation.	23398210
Anxiety, CTCAE 3.0, Inflammation, Neurobehavioral Manifestations, Depression, CTCAE	Altered Intercellular Communication	Differential association of somatic and cognitive symptoms of depression and anxiety with inflammation: findings from the Netherlands Study of Depression and Anxiety (NESDA).	23399050
Anxiety, CTCAE 3.0, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Depression and anxiety have been suggested to be associated with systemic inflammation upregulation.	23399050
Inflammation, Medically Unexplained Symptoms, Anxiety, CTCAE 3.0, Depression, CTCAE	Altered Intercellular Communication	There are some indications that associations with inflammation are mainly driven by somatic symptoms of depression and anxiety.	23399050
Anxiety, CTCAE 3.0, Inflammation, Neurobehavioral Manifestations, Depression, CTCAE	Altered Intercellular Communication	We therefore set out to evaluate the differential association of somatic and cognitive symptoms of depression and anxiety with inflammation, while adjusting for demographic, health related, and lifestyle related variables.	23399050
Anxiety, CTCAE 3.0, Medically Unexplained Symptoms, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Especially somatic symptoms of depression and anxiety are associated with inflammation.	23399050
Inflammation, Fibrosis Assessment, Injury of kidney	Altered Intercellular Communication	Activation of the CD40 receptor on the proximal tubular epithelium of the kidney results in fibrosis and inflammation in experimental models of kidney injury.	23399713
Inflammation, Periodontal Diseases	Altered Intercellular Communication	In vivo inflammation mapping of periodontal disease based on diffuse reflectance spectral imaging: a clinical study.	23400418
Inflammation, GDC Disease Response Terminology	Altered Intercellular Communication	The DR image ratio R620/R575 computed for each pixel (8-um resolution) from the monochrome images is pseudo-color-mapped to identify gingival inflammation sites.	23400418
Inflammation, GDC Disease Response Terminology	Altered Intercellular Communication	The DR image ratio values at each site are compared with clinical diagnosis to estimate the specificity and sensitivity of the DR imaging technique in inflammation mapping.	23400418
Inflammation, Periodontitis	Altered Intercellular Communication	The high diagnostic accuracy is utilized to detect underlying inflammation in six patients with a previous history of periodontitis.	23400418
Inflammation	Altered Intercellular Communication	Diffuse large B-cell lymphoma associated with chronic inflammation in metallic implant.	23401446
Chronic heart failure, Impaired exercise tolerance	Altered Intercellular Communication	Hormonal imbalance in relation to exercise intolerance and ventilatory inefficiency in chronic heart failure.	23402947
Inflammation, physiopathological, SMAD1 protein, human	Altered Intercellular Communication	Our study suggests that skin inflammation reduces the expression of FLG-like proteins, contributing to the AD-related epidermal barrier dysfunction.	23403047
Inflammation, Cholestasis, Necrosis	Altered Intercellular Communication	A variety of non-specific features such as fatty change, mild inflammation, cholestasis and focal necrosis were seen in the other UCD patients.	23403242
Behavioral and psychological symptoms of dementia, Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Biomarkers of vascular risk, systemic inflammation, and microvascular pathology and neuropsychiatric symptoms in Alzheimer's disease.	23403534
Inflammation, "Alzheimers Disease", Mental disorders, Data types - Address	Altered Intercellular Communication	Numerous serum and plasma based biomarkers of systemic inflammation have been linked to both neuropsychiatric disorders and Alzheimer's disease (AD).	23403534
Behavioral and psychological symptoms of dementia, Inflammation, Mental disorders, Data types - Address	Altered Intercellular Communication	A combination of biomarkers of systemic inflammation, microvascular pathology, and clinical biomarkers of cardiovascular risk can account for a significant portion of the variance in the occurrence of neuropsychiatric symptoms in AD supporting a vascular and inflammatory component of psychiatric disorders found in AD.	23403534
Helicobacter pylori, Gastritis	Altered Intercellular Communication	LAB extracts could inhibit the bacterial adhesion and invasion, gastric inflammation and DNA fragmentation induced by Helicobacter pylori.	23404362
Parkinson Disease, Inflammation, "Alzheimers Disease", Nervous system problem	Altered Intercellular Communication	Literature indicated that chronic inflammation might be a factor in developing neurological problems, including Alzheimer's, Parkinson's and other similar illnesses.	23404438
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Escalated levels of monocytes and neutrophils are hallmarks of chronic inflammation and may be precursor to Alzheimer's disease.	23404438
Inflammatory, Communicable Diseases	Altered Intercellular Communication	A low lymphocyte count specifies that the body's resistance to fight infection is substantially reduced, whereas low basophil levels indicates their over utilization due to chronic allergic inflammatory condition.	23404438
Inflammation, Obesity, Bipolar Disorder	Altered Intercellular Communication	Longitudinal associations between obesity, inflammation, and depressive symptoms amongst a cohort of older English adults over 4 years of follow-up were examined.	23404927
Inflammation, Obesity, Bipolar Disorder	Altered Intercellular Communication	These data suggest that chronic inflammation may be a key determinant of depressive symptoms in obesity.	23404927
Pain Distress Question, Inflammation	Altered Intercellular Communication	Expression level of signaling effectors was similar in control and diseased patients and did not correlate with measures of pain and inflammation.	23404938
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	High fat meal challenges are known to induce postprandial low-grade inflammation and endothelial dysfunction.	23405070
Tumor necrosis, Inflammation, Neoplasms	Altered Intercellular Communication	Thalidomide is a tumor necrosis factor alpha (TNFa) inhibitor which has been found to have abilities against tumor growth, angiogenesis and inflammation.	23405115
Sepsis, Inflammation, Fever, CTCAE, Suprapubic pain	Altered Intercellular Communication	We report the case of a 55-year-old woman who presented at the emergency department with hypogastric pain, fever, clinical signs of sepsis and a critical inflammation syndrome in her blood test values.	23405485
Acute Coronary Syndrome, vascular inflammations, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Vascular inflammation plays a key role in the development of acute coronary syndrome (ACS).	23406538
Inflammation	Altered Intercellular Communication	Pregnancy-associated plasma protein A (PAPP-A) and calprotectin are two of several novel promising markers of inflammation.	23406538
Inflammation	Altered Intercellular Communication	Plasma PON1 and TOS levels may serve as predictors of disease severity in children with AR and both of them appear to be attractive candidates for modulating inflammation in AR.	23406590
Erythema Multiforme, Inflammation, Fever, CTCAE	Altered Intercellular Communication	We report on the case of a 4 years old boy presenting high-grade fever associated with erythema multiforme and evidence of systemic inflammation who showed a good response to prompt treatment with intravenous immunoglobulins.	23406772
Bronchial Hyperreactivity, Airway structure, Chest tightness, Wheezing, Dyspnea	Altered Intercellular Communication	Asthma has been defined as a disease of chronic airway inflammation in which many cells and cellular products participate with variable degrees of airflow obstruction and hyperresponsiveness that lead to recurrent episodes of wheezing, breathlessness, chest tightness, and coughing.	23406941
Inflammation, Infiltration	Altered Intercellular Communication	All eyes showed mild stromal infiltration a few days after the procedure; however, the inflammation was resolved within 1 week.	23407323
Inflammation	Altered Intercellular Communication	Postoperative inflammation may play a crucial role in its pathogenesis.	23407323
Neoplasms	Altered Intercellular Communication	Whereas early surgical resection can significantly reduce tumor mass, there are few data available concerning the control of hormonal secretion and associated symptoms.	23407483
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Reduced antiplatelet effect of aspirin is associated with low-grade inflammation in patients with coronary artery disease.	23407706
Inflammation	Altered Intercellular Communication	NFkB as a potent regulator of inflammation in human adipose tissue, influenced by depot, adiposity, T2DM status, and TNFa.	23408599
Inflammation, Obesity	Altered Intercellular Communication	Central obesity and sub-clinical inflammation increase metabolic risk, this study examined the intracellular inflammatory pathways in adipose tissue (AT) that contribute to this risk.	23408599
Inflammation, Joint swelling, Joint tenderness	Altered Intercellular Communication	In the first year, patients with a high BMI had higher DAS and worse functional ability, with more tender joints and a higher visual analog scale global health, but not more swollen joints and similar systemic inflammation.	23408767
Pain Distress Question, Swelling, Inflammation	Altered Intercellular Communication	Patients with a high BMI experienced more pain, but not more swelling or systemic inflammation.	23408767
Pneumonitis	Altered Intercellular Communication	Overexpression of ApoA1 decreased silica-induced lung inflammation and fibrotic nodule formation.	23409054
Inflammation, Pain Distress Question, Poland Syndrome, Bursitis, Hypertrophy	Altered Intercellular Communication	Haglund's syndrome, which is an inflammation of the bursa and a bony enlargement on the back of the heel that most often leads to painful bursitis, is a rare cause of retrocalcaneal pain.	23409529
Inflammation, Muscular Dystrophy, Facioscapulohumeral	Altered Intercellular Communication	Muscle regeneration and inflammation in patients with facioscapulohumeral muscular dystrophy.	23410246
Inflammation, Muscle (organ)	Altered Intercellular Communication	Inflammation in muscle has been suggested by MRI studies in patients with FSHD1A.	23410246
Inflammation, Sleep Apnea, CTCAE, Hypoxia	Altered Intercellular Communication	Patients with sleep apnea sustain cessation of breath during sleep, leading to intermittent hypoxia, systemic inflammation, and sympathetic activation.	23410566
Inflammation	Altered Intercellular Communication	These results provide evidence that glucose ingestion affects systemic inflammation and oxidative stress.	23410727
Communicable Diseases, Myelitis, Myelitis, Transverse	Altered Intercellular Communication	Transverse myelitis is diagnosed based on the presence of spinal cord inflammation and the absence of infection to the central nervous system.	23411769
Inflammation	Altered Intercellular Communication	At autopsy the most important changes in the brain were focal sub cortical peri-vascular mononuclear inflammation of the cerebral vessels.	23412045
Inflammation	Altered Intercellular Communication	Chronic inflammation can be the cause of development of SCC.	23412122
ARCN1 gene, Inflammation	Altered Intercellular Communication	This novel type of immune remodelling, which predicts an increased capacity to respond to alveolar antigens, is suggested to contribute to aggravated inflammation in COPD.	23412435
Crohn Disease, Inflammation, Granuloma	Altered Intercellular Communication	Crohn's disease was characterized by transmural inflammation and epithelioid granulomas.	23412670
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The relationship between psychological factors, inflammation, and nutrition in patients with chronic renal failure undergoing hemodialysis.	23413658
melanoma	Altered Intercellular Communication	The significance of sarcoidal-type inflammation occurring during treatment of metastatic melanoma with a combination of BRAF and MEK inhibitors is unclear.	23413975
Granulomatous inflammation, Sarcoidosis, Eosinophilic granulomatosis with polyangiitis, Vasculitis, CTCAE	Altered Intercellular Communication	Although scar sarcoidosis is a well-described phenomenon, granulomatous inflammation and vasculitis seen in Churg-Strauss syndrome exclusively manifesting in well-healed surgical scars highlights the unique features seen in this case and draws attention to the concept of locus minoris resistentiae.	23414289
Granulomatous inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	This case also highlights how a skin biopsy in the setting of suspected systemic vasculitis can confirm the presence of vasculitis and/or granulomatous inflammation and obviate the need for more invasive, higher risk procedures such as lung biopsy.	23414289
Inflammation	Altered Intercellular Communication	CRP is synthesized in the liver and may represent a systemic response to local inflammation.	23414296
Inflammation, Vascular System Injuries	Altered Intercellular Communication	PTX3 is synthesized locally at the inflammatory sites and may represent a marker for local inflammation at sites of vessel injury.	23414296
Airway structure, Asthma	Altered Intercellular Communication	In this prospective study in a preschool children cohort, we assessed whether the fraction of exhaled nitric oxide (FeNO), a biomarker of airway inflammation, is associated with asthma at school age.	23414302
Inflammation, Impaired cognition, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation is involved in the pathogenesis of cardiovascular disease and cognitive decline.	23414490
Liver Cirrhosis	Altered Intercellular Communication	Liver biopsy was performed in 31.22%; varying grades of inflammation-fibrosis were found in 63.51% and cirrhosis was found in 12.84%.	23414836
Inflammation, Granulation finding	Altered Intercellular Communication	In all inflammation and granulation tissue developed over the stents, but this could be managed by scraping or balloon compression.	23414854
Sepsis, Inflammation	Altered Intercellular Communication	Elevated biomarkers of inflammation and endothelial cell activation have been associated with severity of sepsis.	23414982
Inflammation, Observation Method - Coagulation, Vascular System Injuries	Altered Intercellular Communication	Recent evidence suggests that circulating microparticles (MPs) contribute to inflammation, coagulation and vascular injury.	23415055
Minimal Disseminated Disease, Depressive disorder	Altered Intercellular Communication	Norepinephrine and glutamate are among several neurotransmitters implicated in the neuropathology of major depressive disorder (MDD).	23415275
Inflammation, Atherosclerosis	Altered Intercellular Communication	Risk factors for atherosclerosis may contribute to chronic low-grade inflammation.	23416719
Granulomatosis with polyangiitis	Altered Intercellular Communication	Wegener's granulomatosis is an uncommon multi-systemic disease characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tracts and general focal necrotizing vasculitis (commonly known as Wegener's triad).	23416832
Inflammation, Irritable Bowel Syndrome	Altered Intercellular Communication	Low-grade inflammation in the rectum of patients with sporadic irritable bowel syndrome.	23417076
Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	However, intestinal low-grade inflammation has been proposed as one of the factors contributing to the development of IBS.	23417076
Inflammation, Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	These findings oppose low-grade inflammation as a pathogenic factor in sporadic IBS.	23417076
Inflammation, Ichthyosis Bullosa of Siemens, Post-infectious disorder	Altered Intercellular Communication	Low-grade inflammation may, however, play an important role in the pathogenesis of a subset of IBS, namely post-infectious IBS (PI-IBS).	23417076
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	The histopathological examination of the right testis and lung biopsy revealed granulomatous inflammation consistent with sarcoidosis.	23417949
Inflammation, Respiratory Distress Syndrome, Newborn, Pneumonia, Viral, Influenza	Altered Intercellular Communication	It is postulated that excess inflammation and cytokine production in obese patients following severe influenza infection leads to viral pneumonitis and/or acute respiratory distress syndrome.	23418448
palladium, Inflammation, Fibrosis Assessment, Elastosis perforans serpiginosa	Altered Intercellular Communication	Encapsulating peritoneal sclerosis (EPS) is a devastating complication of peritoneal dialysis (PD), characterized by marked inflammation and severe fibrosis of the peritoneum, and associated with high morbidity and mortality.	23418565
Airway structure, Asthma	Altered Intercellular Communication	Aberrant apoptosis in asthma contributes to airway inflammation.	23418891
Airway structure	Altered Intercellular Communication	Early apoptosis and fragility of airway epithelial cells and delayed apoptosis of inflammatory lymphocytes can cooperate to increase airway inflammation.	23418891
Autoimmune Diseases, Polyarteritis Nodosa, Inflammation	Altered Intercellular Communication	Classical polyarteritis nodosa (cPN) is a rare autoimmune disease featuring systemic inflammation of middle- and small-sized arteries.	23419691
Inflammation, Frontotemporal Lobar Degeneration	Altered Intercellular Communication	Leukocytes mRNA levels of TMEM40 and LY6G6F and other genes mainly involved in inflammation were significantly higher in patients carrying GRN mutations compared with asymptomatic carriers and other FTLD.	23419701
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Enhanced inflammation associated with the onset of GRN disease might be either related to disease pathogenetic mechanism leading to neurodegeneration or to a compensatory pathway that counteracts disease progression.	23419701
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The endoscopic features of these cancers may be modified by controlling inflammation.	23420575
Granulomatous inflammation, Necrotizing Arteritis, Exudate	Altered Intercellular Communication	Fourteen patients had granulomatous inflammation surrounding a central necrotizing eosinophilic exudate identified in surgical pathology specimens from abdominal surgeries.	23421741
Folliculitis	Altered Intercellular Communication	Current evidence indicates that hair follicle inflammation in AA is caused by a T-cell-mediated autoimmune mechanism occurring in genetically predisposed individuals.	23422615
Inflammation, Edema, Urinary Bladder Fistula	Altered Intercellular Communication	Lack of the prominent inflammation and edema that characterizes both papillary and polypoid cystitis, and absence of a history of recent bladder catheterization and presence of vesical fistula may facilitate the decision to biopsy the lesion.	23423685
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	This study suggests a rapid slowdown of type II collagen degradation and joint inflammation after VS with Hylan G-20 and gives additional information for the validation of accurate biomarkers for OA.	23423846
Neoplasms	Altered Intercellular Communication	The Glasgow Prognostic Score (GPS), an inflammation-based prognostic score including C-reactive protein and albumin, shows significant prognostic value in several types of solid tumors.	23423859
Paranasal Sinus Disorder, Inflammation	Altered Intercellular Communication	CT of the head indicated sinus disease including mucoperiosteal-like thickening of the right maxillary sinus, left mastoid hypoaeration and sclerosis characteristics of chronic inflammation.	23424778
Inflammatory disease of mucous membrane	Altered Intercellular Communication	In this cohort of SBCD patients, clinical disease activity index was not reliable predictors of mucosal inflammation.	23425203
Inflammation, Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	They play an important role in normal tissue remodelling and growth, as well as in many destructive pathological conditions such as inflammation, tumour growth and metastasis.	23425881
Pulpitis	Altered Intercellular Communication	This investigation opens a new opportunity for one contemporary method for the diagnosis of pulp inflammations and monitoring of the inflammatory processes.	23425881
Inflammation, Hypertensive (finding), Metabolic Syndrome X	Altered Intercellular Communication	Irbesartan appears to exert beneficial effects on oxidative stress, inflammation, lipid metabolism and metabolic syndrome, indicating that it may be useful in high-risk hypertensive patients.	23425956
Colorectal Carcinoma	Altered Intercellular Communication	Inflammation underlies the etiology of colorectal cancer (CRC).	23426034
Inflammation, Hyperhomocysteinemia, Colorectal Carcinoma	Altered Intercellular Communication	Hyperhomocysteinemia is associated with inflammation and may be a risk marker for CRC.	23426034
Inflammation, Diverticulitis	Altered Intercellular Communication	Patients taking mesalazine have lower risk of diverticulitis recurrence than patients taking rifaximin because of the lower prevalence of persisting endoscopic and histological inflammation.	23426537
Inflammation, Familial Mediterranean Fever	Altered Intercellular Communication	Endogenous anti-oxidants Paraoxonase 1 and arylesterase levels are important in evaluating the inflammation at the remission period of FMF.	23426541
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In contrast, mucus on colon biopsy specimens from patients with UC with acute inflammation was highly penetrable.	23426893
Refractory anemias, Inflammation, Autoimmune Diseases	Altered Intercellular Communication	These results suggest that in patients with active RA, CD19(+)CD24(hi)CD38(hi) B cells with regulatory function may fail to prevent the development of autoreactive responses and inflammation, leading to autoimmunity.	23427243
Tissue Adhesions, Carcinoma of lung, Pneumonitis	Altered Intercellular Communication	Severe adhesions and lung inflammation are conditions that make lung cancer surgery difficult; a skillful and meticulous surgical technique is required in elderly patients.	23427311
Inflammation, Cerebral Aneurysm	Altered Intercellular Communication	The findings provide radiographic evidence of decreased inflammation in human cerebral aneurysms with daily intake of aspirin using macrophages as a surrogate marker for inflammation.	23428244
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Our new method seems promising since it has the ability to diagnose fibrosis even in the presence of inflammation.	23428852
Inflammation	Altered Intercellular Communication	Atypical presentation of tracheobronchopathia osteochondroplastica: is chronic inflammation a perpetrator?	23428943
Macular Edema, Cystoid, Inflammatory abnormality of the eye	Altered Intercellular Communication	Bromfenac sodium 0.1%, fluorometholone 0.1% and dexamethasone 0.1% for control of ocular inflammation and prevention of cystoid macular edema after phacoemulsification.	23429038
Macular Edema, Cystoid, Acute inflammation	Altered Intercellular Communication	To compare bromfenac sodium 0.1%, fluorometholone 0.1% and dexamethasone 0.1% for the control of postoperative inflammation and prevention of cystoid macular edema (CME) after phacoemulsification.	23429038
Inflammatory abnormality of the eye	Altered Intercellular Communication	Bromfenac sodium cleared the ocular inflammation more rapidly than fluorometholone and dexamethasone.	23429038
Inflammation	Altered Intercellular Communication	However, modified or oxidized albumin may lead to a cycle of accelerated oxidative stress and inflammation involving neutrophil activation.	23429046
Inflammation, Thrombosis, Coronary Artery Disease	Altered Intercellular Communication	Inflammation is implicated in the progression of coronary artery disease and the molecular processes of inflammation and thrombosis are closely intertwined.	23429252
Acute and chronic inflammation, Ulcerative Colitis	Altered Intercellular Communication	Chronic pouch inflammation and risk for new-onset extraintestinal cancers in patients with restorative proctocolectomy for ulcerative colitis.	23429461
Inflammation, Intestinal Cancer, Colitis	Altered Intercellular Communication	In the logistic regression model, older age (odds ratio [OR] = 1.5; 95% CI, 1.2-1.8), left-sided colitis (OR = 12.3; 95% CI, 2.2-67.8), and chronic pouch inflammation (OR = 4.4; 95% CI, 1.5-12.9) were associated with the risk for extraintestinal cancer.	23429461
Inflammation, Intestinal Cancer	Altered Intercellular Communication	Older age and chronic pouch inflammation may be associated with an increased risk for extraintestinal cancer in this cohort.	23429461
Inflammatory abnormality of the eye, Biocompatibility	Altered Intercellular Communication	The allografts were stable and biocompatibile in all 10 cases during the follow-up period, evidenced by maintained clarity of the corneal tissue, absence of clinical signs of immunologic rejection or ocular inflammation, and integrity of the sterile cornea and the conjunctiva over the graft.	23429612
Inflammation, Hemorrhage, Pathologic Neovascularization	Altered Intercellular Communication	Pericardioscopy excluded protrusions, petechial bleeding, neovascularization or inflammation.	23430127
Inflammation, Chronic Kidney Diseases, Coronary heart disease	Altered Intercellular Communication	ALP but not serum phosphate was associated with increased risk of coronary heart disease and overall CVD events which persisted after adjustment for CVD risk factors and markers of inflammation and after exclusion of men with chronic kidney disease (adjusted hazard ratio per SD, 1.19 [1.05, 1.34]; P=0.007 and 1.10 [1.01, 1.21]; P=0.04).	23430618
Inflammation, Autoimmune Lymphoproliferative Syndrome Type 2B	Altered Intercellular Communication	Inflammation is clearly involved in the pathogenesis of DEDs, and there is mounting evidence on the antioxidant and antiinflammatory properties of essential polyunsaturated fatty acids (EPUFAs).	23430672
Kidney Failure, Chronic, Inflammation, Uremia, Atherosclerosis	Altered Intercellular Communication	In summary, serum PBHCit, a footprint of protein carbamylation, predicts increased cardiovascular risk in patients with ESRD, supporting a mechanistic link among uremia, inflammation, and atherosclerosis.	23431074
Carcinogenesis, Stomach Carcinoma, Gastritis	Altered Intercellular Communication	These results have provided evidence that galectin-1 and mainly annexin-A1 are overexpressed in both gastritis and gastric cancer, suggesting a strong association of these proteins with chronic gastric inflammation and carcinogenesis.	23431236
Inflammation, Bacterial Infections, Liver Dysfunction, Liver Cirrhosis	Altered Intercellular Communication	Circulating suPAR levels were increased in patients with decompensated cirrhosis and correlated with the severity of liver dysfunction and systemic inflammation but were not indicative of bacterial infection.	23432143
Crohn Disease, Inflammation	Altered Intercellular Communication	While the Crohn's disease activity index (CDAI) is the gold standard for defining clinical endpoints in Crohn's disease (Crohn's) clinical trials, its ability to distinguish symptoms due to inflammation from those that are non-inflammatory has been questioned.	23432394
Tracheitis	Altered Intercellular Communication	This minimised tracheal inflammation and granulation tissue formation.	23433096
Inflammation, Neoplasms	Altered Intercellular Communication	Histological diagnosis of the facial nerve tumor was IPT probably caused by chronic external ear inflammation induced by epidermal nevi.	23433476
Rheumatoid Arthritis, vascular inflammations, Coronary Artery Disease	Altered Intercellular Communication	The aims were to evaluate the presence and extent of pentraxin 3 depositions in specimens from the outer layers of the aorta and from the internal thoracic artery of patients with coronary artery disease with and without rheumatoid arthritis and to search for relationships between pentraxin 3 and vascular inflammation.	23434196
Inflammation	Altered Intercellular Communication	Pentraxin 3 depositions in the outer aortic layers are common and are related to the local inflammation.	23434196
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Chronic inflammation around nerve bundles, sclerotic fibrosis, and prominent lymphoid follicles with plasma cells were the main features of the mass.	23434261
Diabetic Nephropathy	Altered Intercellular Communication	Tubulointerstitial inflammation plays a key role in the development of diabetic nephropathy (DN).	23434541
Interstitial inflammation	Altered Intercellular Communication	We investigated the role of ATP-P2X4 signaling in NLRP3 inflammasome activation and renal interstitial inflammation characteristic of DN.	23434541
Hypercalcemia, CTCAE, Neoplasms	Altered Intercellular Communication	On the basis of severe hypercalcemia (serum calcium 3.66 mmol/l) and high serum parathyroid hormone level (162.5 pmol/l) the diagnosis of a right sided parathyroid tumour was established.	23434885
Inflammation, Demographics Domain	Altered Intercellular Communication	The pathogenesis of skin inflammation in DM is not well understood.	23434970
Inflammation, Fibrosis Assessment, Anastomosis - action, Pancreatic duct, Pancreatic Anastomotic Leakage	Altered Intercellular Communication	Invagination with duct-to-mucosa anastomosis is a useful technique to prevent pancreatic leakage; however, it is difficult to prevent inflammation and fibrosis around the anastomotic site of PG, and this can lead to anastomotic stricture in patients with a remarkably dilated pancreatic duct (diameter >=7 mm).	23435147
Vitreous inflammatory cells	Altered Intercellular Communication	Vitreous inflammation scores at baseline and at 1 year were statistically significantly reduced in both eyes (p<0.001; p=0.001).	23435191
Inflammation, Kaposi Sarcoma	Altered Intercellular Communication	We compared markers of immunosenescence, naive T cells, activation, and inflammation in CD4+ and CD8+ T cells from antiretroviral-treated participants with new-onset Kaposi's sarcoma (cases, n = 19) and from treated individuals without Kaposi's sarcoma (controls, n = 47).	23435301
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Insulin resistance, inflammation and oxidative stress (OS), are among the mechanisms that have been implicated in pathogenesis of essential hypertension (EH).	23435396
ANOPHTHALMIA AND PULMONARY HYPOPLASIA, Pancreatitis, Pancreatic Ductal Adenocarcinoma	Altered Intercellular Communication	Chronic localized pancreatic inflammation in the form of chronic pancreatitis is an established risk factor for human pancreatic ductal adenocarcinoma (PDAC) development.	23435739
Malignant Neoplasms	Altered Intercellular Communication	Constitutive activation of inflammation-related signal transducer and activator of transcription (Stat)3 signaling has been implicated in the development and progression a number of malignancies, including PDAC.	23435739
Orbital Pseudotumor	Altered Intercellular Communication	Idiopathic orbital inflammation syndrome with retro-orbital involvement: a retrospective study of eight patients.	23437329
Orbital Pseudotumor	Altered Intercellular Communication	Seventy-three patients were diagnosed with idiopathic orbital inflammation syndrome based on clinicoradiological features, with pathological confirmation of nonspecific inflammatory conditions in 47 patients.	23437329
Cephalometric orbitale point, Orbital Pseudotumor	Altered Intercellular Communication	All 8 patients were diagnosed with idiopathic orbital inflammation syndrome after biopsy of the orbital lesion.	23437329
Inflammation	Altered Intercellular Communication	In all 8 patients with retro-orbital involvement, the inflammation spread through the superior orbital fissure.	23437329
Inflammation, Orbital Pseudotumor	Altered Intercellular Communication	The diffuse inflammation with marked sclerosis and hyalinization that we observed in the patients with retro-orbital involvement is consistent with the diagnosis of the sclerosing subtype of idiopathic orbital inflammation syndrome.	23437329
Orbital Pseudotumor	Altered Intercellular Communication	In patients with idiopathic orbital inflammation syndrome, it is important to perform MRI and CT scans to identify possible retro-orbital involvement.	23437329
Orbital Pseudotumor	Altered Intercellular Communication	Seventy-three patients were diagnosed with idiopathic orbital inflammation syndrome based on clinicoradiological features, with pathological confirmation of nonspecific inflammatory conditions in 47 patients.	23437329
Inflammation	Altered Intercellular Communication	Characterization of the role of distinct plasma cell-free DNA species in age-associated inflammation and frailty.	23438186
Inflammation, Cell Death	Altered Intercellular Communication	Plasma cell-free DNA (cf-DNA) has recently emerged as a potential biomarker of aging, reflecting systemic inflammation, and cell death.	23438186
Inflammation, Immunosenescence	Altered Intercellular Communication	We identified the relationships between these cf-DNA species and age-associated inflammation, immunosenescence, and frailty.	23438186
Airway structure, Inflammation, Chronic Obstructive Airway Disease, ARCN1 gene	Altered Intercellular Communication	We have suggested that chronic inflammation of other foregut derivatives might be associated with airway inflammation and amplification of the response to inhaled stimuli such as cigarette smoke leading to chronic obstructive pulmonary disease (COPD).	23438259
Gastritis, Acute and chronic inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	One of the commonest causes of chronic foregut inflammation is gastritis secondary to Helicobacter Pylori infection.	23438259
Airway structure, Inflammation, Asthma	Altered Intercellular Communication	Systemic inflammation is associated with differential gene expression and airway neutrophilia in asthma.	23438328
Airway structure, Inflammation, Asthma	Altered Intercellular Communication	Systemic inflammation is reported to be associated with neutrophilic airway inflammation in asthma, but mechanisms underlying this finding are not well understood.	23438328
Airway structure, Inflammation, Asthma	Altered Intercellular Communication	This study aimed to examine the molecular mechanisms of the airway neutrophilia that are associated with systemic inflammation in asthma.	23438328
Inflammation	Altered Intercellular Communication	Asthmatics with systemic inflammation (n=18, 36%) had a higher BMI, greater history of cigarette smoking, lower FVC% predicted, and increased sputum neutrophils compared to those without systemic inflammation (n=16, 32%).	23438328
Airway structure, Inflammation, Asthma	Altered Intercellular Communication	Systemic inflammation was associated with airway neutrophilia in asthma, and was related to a group of differentially expressed genes in the lung involving multiple cytokine pathways.	23438328
Inflammation	Altered Intercellular Communication	Our findings suggest that targeting systemic inflammation might provide a novel therapeutic strategy for neutrophilic asthma.	23438328
Inflammation, Pancreatitis	Altered Intercellular Communication	Acute pancreatitis is an initially localized inflammation of the pancreatic gland.	23438852
Hemorrhage	Altered Intercellular Communication	The concentric alternating zones of hypo/hyper/iso/intensities corresponded to zones of hemorrhage/fibrin-rich necrosis with edema/coagulative compact necrosis/inflammation with foamy histiocytes admixed with hemorrhage forming the outermost zone, respectively.	23440973
Inflammation, Hypercholesterolemia, Dysglycemia, Electrocardiogram: left ventricle hypertrophy (finding), Kidney Diseases, Hypertension, CTCAE	Altered Intercellular Communication	These associations became non-significant after adjusting for obesity-related conditions (hypertension, dysglycemia, hypercholesterolemia, left ventricular hypertrophy, kidney disease, and inflammation).	23441088
Airway structure, Allergic asthma, Asthma, Acid reflux	Altered Intercellular Communication	Pattern of airway inflammation and remodelling in mild persistent atopic asthma and in mild persistent asthma related to gastroesophageal reflux.	23441441
Airway structure, Asthma, Atopy	Altered Intercellular Communication	Atopic GER-related asthma showed two distinct patterns of airway inflammation.	23441441
Airway structure	Altered Intercellular Communication	The eosinophilic contribution to airway inflammation was systematically prevailing in the former group, such as: EOS = 10.7% +/- 13.4 sd vs 2.0% +/- 2.8 sd, p = 0.001; ECP = 344.9 mcg/l +/- 635.9 sd vs 59.2 mcg/l +/- 75.1 sd, p = 0.001.	23441441
Inflammation, Neoplasms	Altered Intercellular Communication	NIS expression in salivary glands is decreased during inflammation and tumor formation.	23441638
Inflammation, Psoriasis	Altered Intercellular Communication	Morphometric study of microvessels, epidermal characteristics and inflammation in psoriasis vulgaris with their correlations.	23442461
Inflammation, Psoriasis	Altered Intercellular Communication	Vascular proliferation, inflammation and epidermal changes are important features in the pathogenesis of psoriasis.	23442461
Inflammation, Psoriasis	Altered Intercellular Communication	Inflammation, microvessels and epidermal parameters were assessed in 50 newly diagnosed cases of psoriasis vulgaris (between 01 Nov 2008 and 31 Oct 2011) by morphometry.	23442461
Inflammation, Psoriasis	Altered Intercellular Communication	It is likely that inflammation is a key factor in the pathogenesis of psoriasis.	23442461
Inflammation, Asthma	Altered Intercellular Communication	Distribution of sputum cellular phenotype in a large asthma cohort: predicting factors for eosinophilic vs neutrophilic inflammation.	23442497
Airway structure, Asthma	Altered Intercellular Communication	Phenotyping asthma according to airway inflammation allows identification of responders to targeted therapy.	23442497
Airway structure, neutrophilic	Altered Intercellular Communication	Eosinophilic (>=3%) and neutrophilic (>=76%) airway inflammation were observed in 46% and 18% of patients respectively.	23442497
Inflammation, Tumor necrosis	Altered Intercellular Communication	SP suppressed the inflammation marker tumour necrosis factor-a in spleen tissue.	23442612
Communicable Diseases, Inflammation	Altered Intercellular Communication	These results suggest that major dietary proteins might affect infection and inflammation by L. monocytogenes.	23442612
Inflammation, Colorectal Carcinoma, Adenoma of large intestine	Altered Intercellular Communication	Given the evidence linking inflammation and colorectal cancer, we sought to determine if plasma endotoxin concentrations are associated with indicators of systemic or local inflammation and colorectal adenomas.	23442743
FAM126A gene	Altered Intercellular Communication	HCC may play an important role in protecting normal conjunctiva, and regulating inflammatory conditions of the anterior ocular surface.	23442876
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Inflammation is an important contributor to pediatric and adult neurodegeneration.	23443029
Inflammation, Impaired cognition, Cerebrovascular accident	Altered Intercellular Communication	Inflammation may contribute to cognitive impairment after stroke.	23444307
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	We tested whether markers of inflammation, erythrocyte sedimentation rate (ESR), and serum levels of C-reactive protein are associated with reduced hippocampal volume and poor cognitive performance among stroke survivors.	23444307
Inflammation	Altered Intercellular Communication	ESR remained unchanged in follow-up examinations, suggesting a chronic inflammation background in some patients.	23444307
skin damage, Inflammation	Altered Intercellular Communication	Exposure to ultraviolet (UV) radiation causes various forms of acute and chronic skin damage, including immunosuppression, inflammation, premature aging and photodamage.	23445687
Inflammation, Cirrhotic	Altered Intercellular Communication	Peripheral blood was obtained from 22 cirrhotic patients with systemic inflammation, 13 cirrhotic patients without systemic inflammation and 14 healthy controls.	23446058
Inflammation, Cirrhotic	Altered Intercellular Communication	These findings were most pronounced in cirrhotic patients with systemic inflammation but fell short of reaching statistical significance when comparing against cirrhotic patients without systemic inflammation.	23446058
Inflammation, Endotoxemia, Liver Cirrhosis	Altered Intercellular Communication	Our data suggest that bacterial translocation, endotoxaemia, inflammation and T cell activation in cirrhosis are accompanied by an increase in circulating anti-inflammatory cytokines, reduced monocytic MHC class II expression and attenuated cytokine production in T cells.	23446058
Inflammation, Infection	Altered Intercellular Communication	Patients become more susceptible to infections and to lymphoproliferation and granulomatous inflammation.	23446300
Communicable Diseases, Heart Septal Defects, Inflammation	Altered Intercellular Communication	The authors hypothesized that the patient had enlarged an existing nasal septal defect due to repetitive nose picking resulting in recurrent infection and inflammation of sinuses, leading to erosion of his medial orbital wall.	23446305
Inflammation, Primary acquired nasolacrimal duct obstruction	Altered Intercellular Communication	Pathological origin of primary acquired nasolacrimal duct obstruction (PANDO) is considered as inflammation of unknown causes; however, specific predisposing factors have not been fully addressed to date.	23446557
Infective conjunctivitis, Inflammation	Altered Intercellular Communication	Histories of infectious conjunctivitis and swimming pool exposure could be associated with the development of PANDO, although the pathogenesis of this condition has been considered as inflammation of unknown causes.	23446557
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Inflammation has been demonstrated to play a central role in the pathogenesis of chronic rhinosinusitis (CRS), and TNFa is a key pro-inflammatory cytokine with important functions in these processes.	23446846
Inflammation	Altered Intercellular Communication	Nerve pathology showed inflammation around the endoneurial microvessels and subperineurial edema and inflammation.	23447136
Inflammation, Fatty degeneration	Altered Intercellular Communication	Both serum and liver desmosterol levels correlated positively with steatosis and inflammation in the liver (P < 0.05).	23447451
Gastroenteritis, Gastrointestinal inflammation, Viral gastroenteritis	Altered Intercellular Communication	The data correlate to the severe inflammatory gastroenteritis seen in patients infected with C. jejuni/coli, whereas C. concisus-infected patients have a much lower intestinal inflammation which could be compared with viral gastroenteritis.	23448294
Inflammation, Bronchospasm	Altered Intercellular Communication	While a number of the consequences of mast cell degranulation within tissues have been documented including tissue-specific changes such as bronchospasm and the subsequent cellular infiltrate, there is little known about the immediate effects of mast cell degranulation on the associated vasculature, critical to understanding the evolution of mast cell dependent inflammation.	23451084
Inflammation, Chronic pain	Altered Intercellular Communication	The authors conducted study to analyze results of peri-articular steroid injection in the treatment of chronic pain from soft tissue inflammation after total knee arthroplasty (TKA).	23451438
Pain Distress Question, chronic, Inflammation	Altered Intercellular Communication	Local steroid injection is a safe and effective choice for treatment of pain from chronic soft tissue inflammation after TKA.	23451438
helium, Inflammation, Status Epilepticus	Altered Intercellular Communication	Occurrence of status epilepticus in HE could be related to the presence of active inflammation of cortical or para-cortical tissue, although such a hypothesis remains to be demonstrated.	23452828
Inflammation, Chronic infectious disease	Altered Intercellular Communication	IL-10-producing regulatory B cells suppress immune responses, and lack of these cells leads to exacerbated symptoms in mouse models of chronic inflammation, transplantation, and chronic infection.	23453135
Inflammation, Osteolysis, Tuberculosis, Osteoarticular	Altered Intercellular Communication	The first patient was followed up for 3 years, during which she experienced mutilating osteolysis of the fingers and very severe inflammation as assessed by osteoarticular ultrasonography.	23453469
Inflammation, Rheumatoid Arthritis, Superficial ulcer	Altered Intercellular Communication	The bone texture parameter Hmean is influenced by age, inflammation and local erosions in rheumatoid arthritis.	23453476
Inflammation	Altered Intercellular Communication	Host-induced antibodies and their contributions to cancer inflammation are largely unexplored.	23454746
Inflammation, Neoplasms, melanoma	Altered Intercellular Communication	Since Th2-biased inflammation is a hallmark of tumor microenvironments, we investigated the presence and functional implications of IgG4 in malignant melanoma.	23454746
Inflammation, Neoplasms	Altered Intercellular Communication	Consistent with Th2 inflammation, CD22+ B cells and IgG4(+)-infiltrating cells accumulated in tumors, and IL-10, IL-4, and tumor-reactive IgG4 were expressed in situ.	23454746
Inflammation, Neoplasms	Altered Intercellular Communication	These findings suggest that IgG4 promoted by tumor-induced Th2-biased inflammation may restrict effector cell functions against tumors, providing a previously unexplored aspect of tumor-induced immune escape and a basis for biomarker development and patient-specific therapeutic approaches.	23454746
Inflammation	Altered Intercellular Communication	One inflammation SNP, rs950286, was successfully replicated with a concordant odds ratio of 1.46 (1.14-1.87) in discovery, 1.37 (1.05-1.77) in replication, and a combined odds ratio of 1.40 (1.17-1.68).	23454887
Single organ dysfunction, Inflammation, cell injury	Altered Intercellular Communication	These symptoms seem to be due to extravasation of gasoline from vessels which lead to inflammation, cell damage and organ failure.	23456531
Refractory anemias, Inflammation	Altered Intercellular Communication	Despite a lack of effect on central BMD, the modest effect of anti-TNF on PIP BMD may provide evidence that BTM reflect specifically bone remodeling activity at periarticular sites of inflammation in RA and PsA.	23457381
Communicable Diseases	Altered Intercellular Communication	In addition, microRNAs affect all facets of the immune/inflammation responses to infection, which may control HPV clearance.	23457596
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	An increase in NLR has been associated with vascular endpoints reflecting inflammation in atherosclerotic lesions.	23457609
Airway structure	Altered Intercellular Communication	Many common diseases affecting the airways are characterized by airway inflammation.	23457675
Inflammation, Gastritis, Mucous Membrane, Conization, Intestinal metaplasia	Altered Intercellular Communication	The gastric biopsies of the patients were also histologically examined to ascertain the presence, nature and degree of the following histological variables of gastritis: colonisation by H. pylori; inflammation, intestinal metaplasia and mucosal atrophy.	23457877
Inflammation, Malaria	Altered Intercellular Communication	One of the main host genetic factors involved in inflammation, immune responses and pathogenesis of malaria is FcgRIIa (cd32) gene.	23458236
Inflammation, Injury of cardiac valve, Traumatic injury	Altered Intercellular Communication	The study aimed to determine if there was an early association between inflammation and secondary cardiac injury in trauma patients.	23459112
Cessation of life, Inflammation, Injury of cardiac valve	Altered Intercellular Communication	Biomarker evidence of cardiac injury and inflammation on admission is associated with a higher risk of in-hospital death.	23459112
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation is considered a central component of asthma and, therefore, international guidelines recommend antiinflammatory medications.	23460164
Inflammation, Endothelial dysfunction, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	We examined the association between job strain and coronary heart disease (CHD) and investigated the role of markers of inflammation and endothelial dysfunction as possible mediators of job strain-associated CHD risk.	23460721
Inflammation, Acquired Immunodeficiency Syndrome, HIV	Altered Intercellular Communication	Monocytes and myeloid dendritic cells (mDCs) are important orchestrators of innate and human immunodeficiency virus (HIV)-specific immune responses and of the generalized inflammation that characterizes AIDS progression.	23460749
Inflammation, hepcidin	Altered Intercellular Communication	Iron status and systemic inflammation, but not gut inflammation, strongly predict gender-specific concentrations of serum hepcidin in infants in rural Kenya.	23460869
Inflammation, Anemia	Altered Intercellular Communication	Prevalence of inflammation, anemia, and iron deficiency was 31%, 71%, 26%, respectively.	23460869
Inflammation, hepcidin	Altered Intercellular Communication	We propose gender-specific reference values for serum hepcidin in iron-replete infants without inflammation.	23460869
Granulomatous inflammation, Sarcoidosis, Lesion of vulva	Altered Intercellular Communication	Biopsy results showed non-caseous granulomatous inflammation consistent with sarcoidosis in the vulvar lesion.	23461079
Orbital Pseudotumor	Altered Intercellular Communication	It's a rare disease entity which runs as a idiopathic inflammation of retina and choroid.	23461159
Neoplasms	Altered Intercellular Communication	Most tumors (3/5) exhibited predominantly endocrine differentiation without hormonal production.	23462323
Pelvic abscess, Inflammation	Altered Intercellular Communication	In vivo MR-guided freehand drainage was prospectively performed in patients with increased systemic inflammation markers and abdominal, retroperitoneal, and pelvic abscess collections.	23462676
Inflammation, Pancreatic carcinoma	Altered Intercellular Communication	Chronic inflammation may play a role in the development of pancreatic cancer.	23462920
Inflammation, Pancreatic carcinoma	Altered Intercellular Communication	In conclusion, prediagnostic levels of circulating CRP, IL-6, and TNF-aR2 were not associated with the risk of pancreatic cancer, suggesting that systemic inflammation as measured by circulating inflammatory factors is unlikely to play a major role in the development of pancreatic cancer.	23462920
Postprandial Period	Altered Intercellular Communication	No consistent significant postprandial inflammation, oxidative stress or regulation of adiponectin was observed in this study.	23462948
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Elevated high-sensitivity C-reactive protein (hs-CRP), a marker of low-grade systemic inflammation, may be involved in the etiology of type 2 diabetes mellitus (T2DM).	23463453
Inflammation, Obesity	Altered Intercellular Communication	However, whether inflammation precedes development of T2DM independent of cigarette smoking and obesity remains to be confirmed.	23463453
Inflammation, Obesity	Altered Intercellular Communication	These findings imply that higher hs-CRP itself or existence of chronic systemic inflammation precedes onset of T2DM independent of obesity and smoking.	23463453
Inflammation, Carpal Tunnel Syndrome	Altered Intercellular Communication	Chondrocalcinosis was responsible for the systemic inflammation, the CTS, the pisotriquetral joint effusion, and the UDBM compression, which has not been reported previously.	23463648
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is associated with persistent inflammation and oxidative stress in susceptible individuals.	23463699
Pneumonitis	Altered Intercellular Communication	Analysis of bronchial biopsy samples showed a very strong correlation between Wnt4 and IL8 gene expression, suggesting that Wnt4 plays a role in chronic lung inflammation.	23463699
Inflammation, Neutrophil Infiltration	Altered Intercellular Communication	Wnt4, in turn, acts through the noncanonical pathway to activate epithelial cell remodeling and IL8 gene expression, leading to neutrophil infiltration and inflammation.	23463699
Inflammation, Acidosis	Altered Intercellular Communication	Cytokine secretion and markers of inflammation in relation to acidosis among chronic hemodialysis patients.	23463880
Vaginitis, Inflammation, Cervix Erosion	Altered Intercellular Communication	Gynecologic examinations revealed cervical erosion in 8 (1.6%), vaginitis in 193 (37.7%) and normal findings in 311 (60.7%); pathological evaluation reports of the smears were negative in 290 (56.6%), inflammation in 218 (42.6%) and ASC-US in 4 (0.8%), according to the 2001 Bethesda classification.	23464481
Granuloma, Inflammation	Altered Intercellular Communication	Granuloma cells in chronic inflammation express CD205 (DEC205) antigen and harbor proliferating T lymphocytes: similarity to antigen-presenting cells.	23464965
Granuloma, Granulomatous inflammation	Altered Intercellular Communication	Of these, the immune granulomas, a hallmark of granulomatous inflammation, are closely related to cell-mediated immune responses.	23464965
Inflammation	Altered Intercellular Communication	This may substantiate elevated s-TG and lowered s-HDL as markers or inducers of inflammation associated disease.	23465506
Inflammation, atherosclerotic	Altered Intercellular Communication	Our findings suggest interwoven actions of poor glycemic control, low grade inflammation and low HDL-c on atherosclerotic processes in type 2 diabetes.	23466074
vascular inflammations, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Collectively, these findings demonstrate that enhanced CYP o-hydroxylase and sEH metabolic function are associated with more advanced endothelial dysfunction and vascular inflammation, respectively, in patients with established atherosclerotic cardiovascular disease.	23466098
Inflammation, Crohn Disease	Altered Intercellular Communication	Endomicroscopic analysis of major axis/minor axis ratio allows the detection of microscopic residual inflammation with greater accuracy than standard endoscopy in Crohn's disease patients in clinical remission.	23466186
Inflammation, Anemia	Altered Intercellular Communication	In addition, pre- and post-menopausal women in the lower 25-hydroxyvitamin D group were at a higher risk of iron deficient anemia and anemia of inflammation.	23466602
Inflammation, Postmenopausal state	Altered Intercellular Communication	These data suggest that adipokines and systemic inflammation may be associated with the risk of postmenopausal breast cancer independently of BMI.	23466816
Inflammation, Contracture, Microbial Biofilms	Altered Intercellular Communication	It has been hypothesized that bacterial biofilms on breast implants may cause chronic inflammation leading to capsular contracture.	23468161
Inflammation, Ischemic stroke, Haiti	Altered Intercellular Communication	Identified genes correspond to differences in inflammation and coagulation that may predispose to HT in ischemic stroke.	23468366
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	In inflammatory bowel disease (IBD), genetic susceptibility together with environmental factors disturbs gut homeostasis producing chronic inflammation.	23468882
Inflammation	Altered Intercellular Communication	A meta-analysis including all available, comparable data was used to explore important aspects of IBD inflammation, thereby validating consistent gene expression patterns.	23468882
Respiratory Insufficiency, Inflammation	Altered Intercellular Communication	Respiratory impairment and systemic inflammation in cedar asthmatics removed from exposure.	23468925
Respiratory Insufficiency, Asthma, Inflammation	Altered Intercellular Communication	Years after exposure cessation, patients with Western red cedar asthma have persistent airflow obstruction and respiratory impairment, associated with systemic inflammation.	23468925
Inflammation, Albuminuria, Chronic Kidney Diseases	Altered Intercellular Communication	Although previous evidence has shown that angiopoietin-2 destabilizes vasculature and induces inflammation in different scenarios, further study will be required to delineate the role of angiopoietin-2 in albuminuria and microinflammation in CKD patients.	23469160
Inflammation, asthma chronic	Altered Intercellular Communication	Th17-related responses drive inflammation during late stages of chronic asthma and can also be blocked by ustekinumab.	23469809
Inflammatory Bowel Diseases, Inflammation, Rheumatoid Arthritis, Spondylitis	Altered Intercellular Communication	MPV is inversely correlated with inflammation in inflammatory bowel diseases, rheumatoid arthritis, and ankylosing spondylitis, as shown in the previous studies.	23469987
Degenerative polyarthritis, Inflammation, Synovitis	Altered Intercellular Communication	MPV levels may be considered as a marker of inflammation but further comprehensive prospective trials are needed in osteoarthritis associated with synovitis patients.	23469987
Inflammation, Obesity	Altered Intercellular Communication	In women, obesity is correlated with low-grade inflammation and recent data show that BMI is positively associated with thrombin generation.	23470648
Inflammation, Thrombus, Venous Thrombosis, Obesity	Altered Intercellular Communication	We explored the correlations between obesity, inflammation and thrombin generation in women with increased thrombotic risk by looking at a cohort of women with prior venous thrombosis.	23470648
Inflammation, Thrombosis, Obesity	Altered Intercellular Communication	This shows a possible link between obesity, low-grade inflammation and increased thrombin generation in women at increased risk for future thrombosis.	23470648
Inflammation, Choroidal ischemia	Altered Intercellular Communication	Fluorescence angiography and indocyanine green-angiography disclosed focal choroidal ischaemia in the area of inflammation.	23470676
Inflammation, Hereditary hemochromatosis, home health encounter, fibrogenesis	Altered Intercellular Communication	Hereditary hemochromatosis (HH) is characterized by accumulation of iron, oxidative stress, inflammation, and fibrogenesis in liver tissue.	23471031
Inflammation, Hyperparathyroidism	Altered Intercellular Communication	ESA requirements are independent of age when dose is scaled to body surface area, and ESA resistance is associated with inflammation, fluid retention, and hyperparathyroidism.	23471197
Coughing, ARCN1 gene, Airway structure	Altered Intercellular Communication	To quantify cough frequency in an unselected group of subjects with COPD and investigate the relationships between cough, reported sputum production, smoking, pulmonary function, and cellular airway inflammation.	23471467
Coughing, ARCN1 gene, Airway structure	Altered Intercellular Communication	Ambulatory objective monitoring provides novel insights into the determinants of cough in COPD, suggesting sputum production, smoking, and airway inflammation may be more important than sensitivity of the cough reflex.	23471467
Inflammation, therapeutic hemodilution, hafnium, Anemia, Renal Insufficiency	Altered Intercellular Communication	Contributors to the risk of anemia in HF include hemodilution, renal dysfunction and inflammation.	23472188
Kidney Failure, Chronic, Communicable Diseases, Inflammation, Chronic kidney disease stage 5	Altered Intercellular Communication	Inflammation induced by infectious and noninfectious triggers in the kidney may lead to end stage renal disease (ESRD).	23472199
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	Chronic rhinosinusitis with nasal polyps is characterized by B-cell inflammation and EBV-induced protein 2 expression.	23473835
Inflammation, Craniosynostosis	Altered Intercellular Communication	B cells and plasma cells are enriched in NPs, actively produce antibodies locally, and might contribute to chronic inflammation in patients with CRS.	23473835
Inflammatory abnormality of the eye	Altered Intercellular Communication	Apart from the abnormal vasculature, there were no signs of chronic ocular surface inflammation.	23474249
Inflammation, Data types - Address, CRNKL1 wt Allele, Liver Cirrhosis	Altered Intercellular Communication	We analyzed data from patients with cirrhosis and AD to establish diagnostic criteria for ACLF and showed that it is distinct from AD, based not only on the presence of organ failure(s) and high mortality rate but also on age, precipitating events, and systemic inflammation.	23474284
Inflammation, Osteolysis	Altered Intercellular Communication	Interleukin-17C was related to the inflammation of aseptic loosening, possibly by contributing to the inflammation and osteolysis in the tissues surrounding aseptic loosened implants.	23474800
Malignant tumor of colon, Adiponectin Deficiency	Altered Intercellular Communication	Mucus and adiponectin deficiency: role in chronic inflammation-induced colon cancer.	23474825
Malignant tumor of colon	Altered Intercellular Communication	This study aims to define the role of adiponectin (APN) in preventing goblet cell apoptosis and in differentiation of epithelial cells to goblet cell lineage resulting in greater mucus production and hence greater protection from chronic inflammation-induced colon cancer (CICC).	23474825
Inflammation	Altered Intercellular Communication	Chronic inflammation was induced in DSS and DSS + DMH group by administrating 2 % DSS in drinking water for 5 days followed by 5 days of normal drinking water and this constitutes one DSS cycle.	23474825
Inflammation	Altered Intercellular Communication	Three cycles of DSS were administered to induce chronic inflammation.	23474825
Refractory anemias, Inflammation	Altered Intercellular Communication	Colour Doppler activity is associated with the extent of inflammation present in the synovial biopsies from RA patients.	23475981
Inflammation	Altered Intercellular Communication	Recently, the chronic inflammation has been proposed to be involved in the pathogenesis of IR.	23476101
Inflammation, Progranulins, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	These results suggested that Plasma progranulin concentrations were higher in Chinese patients with type 2 diabetes and obesity and correlated closely with glycolipid metabolism, chronic inflammation and IR.	23476101
Inflammation	Altered Intercellular Communication	Retrospective reports of weight change and inflammation in the US National Health and Nutrition Examination Survey.	23476750
Weight Gain, Inflammation, Weight decreased	Altered Intercellular Communication	The increased risk of elevated CRP among individuals who experienced at least 10 kg of weight loss or weight gain was also observed for weight change that occurred over the past 10 years; however, weight loss over the 10-year period was no longer associated with high inflammation.	23476750
Inflammation, Weight decreased	Altered Intercellular Communication	These results suggest that adult respondents who retrospectively self-reported weight loss or gain had higher levels of inflammation relative to their weight stable counterparts.	23476750
trauma to the abdomen, Neoplasms	Altered Intercellular Communication	Chyloascites is a rare complication that can result from abdominal trauma, neoplasm, inflammatory conditions, or various abdominal surgeries.	23477184
Inflammatory Bowel Diseases	Altered Intercellular Communication	IBD is a chronic inflammatory condition that is usually diagnosed in young adulthood.	23477328
Stomach Carcinoma, Gastritis	Altered Intercellular Communication	This study is designed to assess the levels of CRH in gastric tissue of a group of patients with gastric cancer and gastric chronic inflammation.	23477585
Stomach Carcinoma, Gastritis	Altered Intercellular Communication	Fifty-two patients with gastric cancer (GC) and 213 patients with gastric chronic inflammation were recruited into this study.	23477585
Hepatic inflammation	Altered Intercellular Communication	The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study.	23477746
Non-alcoholic Fatty Liver Disease, Hepatic inflammation, Fatty degeneration, Liver Cirrhosis	Altered Intercellular Communication	Nonalcoholic fatty liver disease (NAFLD) ranges from simple steatosis to hepatic inflammation to cirrhosis.	23477746
Non-alcoholic Fatty Liver Disease, Hepatic inflammation	Altered Intercellular Communication	We sought to identify common genetic variants contributing to NAFLD, using CT measured fatty liver (FL), and alanine aminotransferase levels (ALT), as a biochemical marker of hepatic inflammation.	23477746
Hepatic inflammation	Altered Intercellular Communication	Our findings suggest ERLIN1-CHUK-CWF19L1 variants are associated with early stage of FL accumulation (measured by CT) to hepatic inflammation (ALT levels), and the association enhances when accounting for the correlations between their scans.	23477746
Steatohepatitis, Non-alcoholic Fatty Liver Disease, Fatty degeneration, Inflammation	Altered Intercellular Communication	CMA approach enhanced the ability to identify novel variants of the ERLIN1-CHUK-CWF19L1 influencing both simple steatosis and hepatic steatosis with inflammation, which suggest that this gene cluster may regulate the susceptibility of NAFLD in a wide spectrum of disease.	23477746
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	It is associated with type 2 diabetes mellitus and adipose inflammation.	23477808
Splenomegaly, Liver Dysfunction, Pneumonitis, Hyperferritinaemia, Pancytopenia, Pleural Effusion, CTCAE, Disorder of intra-abdominal lymph nodes	Altered Intercellular Communication	Admission examinations showed severe pancytopenia, liver dysfunction, hyperferritinemia, fibrinopenia, elevated lactalase dehydrase, bilateral pulmonary inflammation and pleural effusion, abdominal lymphadenopathy, and splenomegaly.	23478118
Data types - Address	Altered Intercellular Communication	MEG delta mapping might be a serious candidate for a "neural degeneration" marker of AD reflecting dysfunctional synaptic transmission.	23478303
Inflammation, Hypertension, CTCAE, Hypertrophy	Altered Intercellular Communication	We have shown that C-344T potentially predicts higher values of LVMI and concentric hypertrophy in untreated hypertension, independently of renal function and subclinical inflammation.	23479071
Inflammation, Malignant neoplasm of gastrointestinal tract	Altered Intercellular Communication	A strong link between inflammation and gastrointestinal cancer has been demonstrated.	23479179
Communicable Diseases, Stomatitis, Radiation injury, Dermatitis, Treatment-Emergent Adverse Event, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The most common grade 3/4 treatment-emergent adverse events were mucosal inflammation (73%); dermatitis (27%); and infection, radiation skin injury and stomatitis (23% each).	23479383
Inflammation, Pain Distress Question	Altered Intercellular Communication	MR imaging is sensitive for depicting tissue or fluid changes related to inflammation, a common process in causes of acute abdominopelvic pain.	23479698
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	An echogenic skin lesion is most likely benign and can occasionally have peripheral vascularity due to surrounding inflammation.	23479705
Myositis	Altered Intercellular Communication	[18F]FDG uptake in proximal muscles assessed by PET/CT reflects both global and local muscular inflammation and provides useful information in the management of patients with polymyositis/dermatomyositis.	23479721
Myopathy, Myositis	Altered Intercellular Communication	This study aimed to determine whether [(18)F]fluorodeoxyglucose-PET/CT ([(18)F]FDG-PET/CT) discriminates PM/DM from non-muscular diseases and also whether FDG uptake in proximal muscles reflects the activity and severity of muscular inflammation in PM/DM.	23479721
Inflammation	Altered Intercellular Communication	Our results suggest that [(18)F]FDG-PET/CT is useful in the diagnosis of PM/DM when inflammation in proximal muscles is globally assessed with quantitative measurements.	23479721
Inflammation	Altered Intercellular Communication	Our results also indicate that local FDG uptake in a proximal muscle reflects the activity of inflammation in the same muscle and provides useful information in determining the region for muscle biopsy.	23479721
Cataract, Inflammation	Altered Intercellular Communication	To evaluate anterior chamber inflammation in eyes with retained presumed intraocular cotton fibers after small-incision cataract surgery.	23480601
Cataract, Inflammation	Altered Intercellular Communication	Following cataract surgery, retained presumed intraocular cotton fibers did not cause any additional inflammation in the eye within the short term.	23480601
Cataract, Inflammation	Altered Intercellular Communication	In contrast to other intraocular foreign bodies, which may cause severe inflammation, retained intraocular cotton fibers seem to be well tolerated following cataract surgery.	23480601
Orbital Pseudotumor	Altered Intercellular Communication	IgG4 orbital inflammation in a 5-year-old child presenting as an orbital mass.	23480695
Orbital Pseudotumor	Altered Intercellular Communication	It can present as orbital inflammation or as an orbital mass.	23480695
Orbital Pseudotumor	Altered Intercellular Communication	Initially this was reported to be idiopathic orbital inflammation.	23480695
Inflammation, Granuloma, Foreign-Body	Altered Intercellular Communication	Histological reported chronic inflammation with granulomatous foreign body giant cell reaction confirming pre-operative diagnosis of tissue reaction to glue cast.	23480817
Bacteremia, Inflammation	Altered Intercellular Communication	The neutrophil-lymphocyte count ratio (NLR), a convenient marker of inflammation, has been demonstrated to be a useful biomarker for predicting bacteremia.	23482854
Inflammation, Corneal Ulcer	Altered Intercellular Communication	One week later, the inflammation subsided completely while the corneal ulcer healed and visual acuity improved dramatically.	23483491
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Osteoarthritis (OA) is a degenerative joint disease involving a combination of cartilage degradation and inflammation.	23483610
Inflammation, Damage	Altered Intercellular Communication	This paper aims to evaluate the relationship of patient-reported tender and swollen joints with active inflammation as detected by power Doppler (PDUS) and whether this relationship is affected by significant joint damage.	23484455
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Correlations of apelin serum levels with disease activity, systemic inflammation and metabolic syndrome were assessed.	23484462
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	No significant correlation between apelin concentration and demographic features, inflammation, adiposity and metabolic syndrome features was seen.	23484462
Inflammation, senile	Altered Intercellular Communication	(Immunity and inflammation are the defenses against invaders from the environment and responsible for repair of damaged and senile cells.)	23484675
Inflammation, MS gene	Altered Intercellular Communication	High levels of oxidative stress are associated with inflammation and play an important role in pathogenesis of multiple sclerosis.	23485514
Inflammation	Altered Intercellular Communication	In addition, HVC may lead to increased left ventricle mass index and pulmonary artery pressure and decreased ejection fraction, and low albumin levels may be attributable to inflammation.	23485537
Inflammation, Atherosclerosis	Altered Intercellular Communication	However, the mechanism underlying Th17 inflammation in atherosclerosis remains largely unknown.	23485611
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Thymic stromal lymphopoietin (TSLP) is a novel IL-7-like cytokine and mainly responsible for Th2 inflammation in many inflammatory diseases.	23485611
Inflammation, Atherosclerosis	Altered Intercellular Communication	TSLP induced by ox-LDL could promote Th17 immune response in vitro, which may be implicated in Th17 inflammation in atherosclerosis.	23485611
Communicable Diseases, Milroy Disease, Inflammation, Lymphedema	Altered Intercellular Communication	A clinical diagnosis of lymphedema of unknown etiology was made; the hypotheses were that the etiology was late congenital lymphedema of the penis or lymphedema aggravated by inflammation and/or infection.	23485846
Inflammation, Heart failure	Altered Intercellular Communication	In patients with heart failure, increased apoptosis, inflammation and activation of the transforming growth factor (TGF)-b cytokine system have been documented.	23486075
Granulomatous inflammation	Altered Intercellular Communication	This is based on a single colony of mycobacterium isolated, histologic finding revealing granulomatous inflammation, and the favorable response to rifampin.	23486124
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	High ALDO levels within normal range are related to the presence of subclinical inflammation in essential hypertension.	23486351
Appendage, Inflammation, Ischemia	Altered Intercellular Communication	The aim of this case report is to present typical US and CT features of epiploic appendagitis, characterized by the ischemia and inflammation of the epiploic appendices of the colon.	23486629
Clostridium difficile infection, Gastrointestinal inflammation	Altered Intercellular Communication	Markers of intestinal inflammation, not bacterial burden, correlate with clinical outcomes in Clostridium difficile infection.	23487367
Compact Disk Interactive, Inflammation, Communicable Diseases, Clostridium difficile enteritis, Clostridium difficile colitis	Altered Intercellular Communication	To assess the contribution of ongoing infection vs persistent inflammation, we examined the correlation between fecal cytokine levels, fecal C. difficile burden, and disease outcomes in C. difficile infection (CDI).	23487367
Compact Disk Interactive, Diarrhea, Gastrointestinal inflammation	Altered Intercellular Communication	Persistent diarrhea in CDI correlates with intestinal inflammation and not fecal pathogen burden.	23487367
Inflammation, Chronic heart failure	Altered Intercellular Communication	Chronic heart failure (HF) is in part characterized by immune activation and inflammation, and factors that regulate lymphocyte trafficking and inflammation may contribute to the progression of this disorder.	23487539
Cessation of life, Inflammation, Nerve Degeneration	Altered Intercellular Communication	Oxidative stress is a widely recognized cause of cell death associated with neurodegeneration, inflammation, and aging.	23487751
vascular inflammations, Endothelial dysfunction	Altered Intercellular Communication	Besides, its cholesterol-lowering effect, the ability of simvastatin to ameliorate endothelial dysfunction through increasing NO bioavailability and through suppression of oxidative stress and vascular inflammation may play an important role in these effects.	23488690
Inflammation, Alveolar Bone Loss	Altered Intercellular Communication	Oxidative burst activity of peripheral monocytes and granulocytes is elevated in DS affected individuals and may contribute to periodontal tissue inflammation and loss of periodontal attachment in this susceptible group.	23488730
Inflammation, VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding), Pruritus	Altered Intercellular Communication	A total of 125 patients with vitiligo, who showed lesions in particular locations, onset at an older age, and/or pre-existing inflammation or pruritus, were included.	23488983
Inflammation, Impaired cognition	Altered Intercellular Communication	Population-based studies have demonstrated the association of inflammation and cognitive impairment.	23489773
Inflammation, Craniosynostosis	Altered Intercellular Communication	Higher levels of oral and nasal FeNO in ECRS patients may reflect the persistence of eosinophilic inflammation in sinus mucosa with concomitant iNOS upregulation and accompanying deposition of oxidized NO metabolites.	23489830
Inflammation, Osteoporosis	Altered Intercellular Communication	The latest data suggests that inflammation plays a critical role in bone remodeling and in pathogenesis of osteoporosis.	23490023
Inflammation, Malignant Neoplasms, Inflammatory disorder	Altered Intercellular Communication	NLR is a simple, non-invasive and cost-effective marker of inflammation in various malignancies and inflammatory diseases.	23490023
Inflammation, Osteoporosis	Altered Intercellular Communication	Elderly people with osteoporosis have elevated NLR levels, suggesting that inflammation may play an important role in bone remodeling.	23490023
Increased insulin level, Inflammation, Hyperglycemia	Altered Intercellular Communication	A "Western" lifestyle characterized by physical inactivity and excess weight is associated with a number of metabolic and hormonal dysregulations, including increased circulating estrogen levels, hyperinsulinemia, hyperglycemia, and chronic inflammation.	23492765
Increased insulin level, Inflammation, Hyperglycemia	Altered Intercellular Communication	A "Western" lifestyle characterized by physical inactivity and excess weight is associated with a number of metabolic and hormonal dysregulations, including increased circulating estrogen levels, hyperinsulinemia, hyperglycemia, and chronic inflammation.	23492765
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Diabetes is associated with persistent inflammation and defective tissue repair responses.	23493576
Inflammation, Fever, CTCAE, Lymphadenopathy	Altered Intercellular Communication	All patients presented with fever, moderate to highly elevated signs of inflammation, and local lymphadenopathy.	23494111
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Impaired insulin sensitivity (SI) and b-cell function are the two main causes of type 2 diabetes (T2D) and are related to low-grade inflammation status.	23494740
Pain Distress Question, Inflammation, Anger	Altered Intercellular Communication	The majority of participants chose red to describe high-intensity pain; the reasons given were because red symbolized inflammation, fire, anger and the stop signal in a traffic light system.	23495128
Inflammation	Altered Intercellular Communication	Our data show that frailty and mortality rate were positively associated with chronic inflammation and with a down-regulation of multiple endocrine factors.	23496093
Inflammation, Postoperative delirium, Fluctuating consciousness, Inattention, Confusion	Altered Intercellular Communication	To determine whether intraoperative blood transfusion, a known trigger and amplifier of inflammation, is an independent risk factor for early postoperative delirium (POD), an acute state of confusion with fluctuating consciousness and inattention after surgery, in older adults undergoing surgery.	23496244
Inflammation, Helminthiasis	Altered Intercellular Communication	To evaluate systemic serum cytokine and chemokine markers for inflammation and Th1/Th2 responses in relation to multiple helminth infections, parasite burden and/or nutritional status of individuals.	23496801
pertussis vaccine	Altered Intercellular Communication	Furthermore, we measured fractional exhaled nitric oxide (FeNO) with regard to whether we could distinguish eosinophilic inflammation of the airway and pertussis.	23496900
Cerebral Amyloid Angiopathy, Inflammation	Altered Intercellular Communication	Corticosteroid therapy in a patient with cerebral amyloid angiopathy-related inflammation.	23497126
Inflammation	Altered Intercellular Communication	Computed tomography revealed bowel wall thickness and mesentery inflammation at the hepatic flexure of the colon and cecum.	23497155
Irritation - emotion, Urinary Bladder Calculi (disorder), Inflammation	Altered Intercellular Communication	Bladder calculus is associated with chronic irritation and inflammation.	23497224
Malignant neoplasm of urinary bladder, Inflammation, Carcinogenesis, Best Case Imputation Technique	Altered Intercellular Communication	As there is substantial documentation that inflammation can play a direct role in carcinogenesis, to date the relationship between stone formation and bladder cancer (BC) remains unclear.	23497224
Inflammation, Mood Disorders, Filariasis	Altered Intercellular Communication	Filariasis by inducing chronic inflammation and immunopathologic reactions seems to play a major role in infected affective disorders patients by changing levels of cytokines of the Th1 system or indirectly damaging the brain tissue.	23497411
Thrombosis, Sinusitis	Altered Intercellular Communication	Contrast enhanced CT showed dilated left superior ophthalmic vein, suggestive of thrombosis, contrast enhancement of the left cavernous sinuses, and dilation of cavernous sinus, indicating cavernous sinus inflammation.	23497466
Inflammatory abnormality of the eye	Altered Intercellular Communication	Genotypes were correlated with disease characteristics and severity of ocular inflammation.	23497844
Hyperlipidemia, Inflammation, Diabetes Mellitus, Uremia, Hypertension, CTCAE	Altered Intercellular Communication	We hypothesized that AMP patients would display a pro-inflammatory adipokine signature, and that certain clinical conditions (diabetes, hypertension, hyperlipidemia, high BMI, uremia) would independently drive elevated adipose inflammation.	23498310
Inflammation	Altered Intercellular Communication	Related to immunosenescence, a low-grade inflammation also develops with aging contributing also to increase carcinogenesis.	23503514
Pleural Diseases	Altered Intercellular Communication	Thus, dysfunction of both synaptic transmission and auditory neural function can be associated with abnormal loudness adaptation and the magnitude of the adaptation is significantly greater with ribbon synapse than neural disorders.	23503620
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Is perioperative systemic inflammation the result of insufficient cortisol production in patients with colorectal cancer?	23504123
Communicable Diseases, Inflammation, Discitis, Osteomyelitis of vertebra	Altered Intercellular Communication	Vertebral osteomyelitis or discitis is a condition characterised by inflammation to the vertebral disc space and is often related to infection.	23505083
Inflammation, Weight decreased, Metabolic Syndrome X	Altered Intercellular Communication	Effect of the Mediterranean diet with and without weight loss on markers of inflammation in men with metabolic syndrome.	23505168
Inflammation, Weight decreased, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	To investigate the impact of the MedDiet consumed under controlled feeding conditions before (-WL) and after weight loss (+WL) on markers of inflammation in men with metabolic syndrome (MetS).	23505168
Inflammation, Weight decreased	Altered Intercellular Communication	Thus, consuming MedDiet even in the absence of weight loss significantly reduces inflammation.	23505168
Inflammation, Weight decreased, ETV3 wt Allele	Altered Intercellular Communication	However, the degree of waist circumference reduction with weight loss magnifies the impact of the MedDiet on other markers of inflammation associated with MetS in men.	23505168
Inflammation, Fibrosis Assessment, Heart failure	Altered Intercellular Communication	Galectin-3 is a biomarker associated with inflammation and fibrosis that predicts adverse outcome and relates to biomarkers of extracellular matrix turnover in patients with heart failure, particularly when left ventricular (LV) systolic function is preserved.	23505301
Inflammation, Urinary tract infection	Altered Intercellular Communication	b-Hemolysin/cytolysin of Group B Streptococcus enhances host inflammation but is dispensable for establishment of urinary tract infection.	23505569
Inflammation, Urinary tract infection	Altered Intercellular Communication	Given the near ubiquity of bH/C-expressing strains in epidemiologic studies and the importance of local inflammation in dictating outcomes and sequelae of UTI, we hypothesize that bH/C-driven inflammatory signaling may be important in the clinical course of GBS-UTI.	23505569
Inflammation, Urinary tract infection	Altered Intercellular Communication	Given the near ubiquity of bH/C-expressing strains in epidemiologic studies and the importance of local inflammation in dictating outcomes and sequelae of UTI, we hypothesize that bH/C-driven inflammatory signaling may be important in the clinical course of GBS-UTI.	23505569
Inflammation, AHSG protein, human, Coronary Arteriosclerosis	Altered Intercellular Communication	Fetuin-A inhibits inflammation and has a protective effect against myocardial ischemia.	23505907
Inflammation, BDI - Functional Impairment, Swelling, Chronic inflammatory disorder, Arthritis	Altered Intercellular Communication	Arthritis is a chronic inflammatory disease resulting in inflammation of diarthrodial joints (particularly joints of hands, wrists, feet, knees, ankles, and shoulders), manifested by swelling and functional impairment.	23505920
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	In conclusion, our observations suggest that ACS shows an increase in both remodeling and inflammation markers.	23505923
Lymphocyte count decreased, Inflammation, Critical Illness, Bacteremia	Altered Intercellular Communication	The neutrophil/lymphocyte count ratio (NLCR) has been introduced as a parameter for systemic inflammation in critically ill patients and was found, together with lymphocytopenia, to be a better predictor of bacteraemia than routine parameters like C-reactive protein and total leukocyte count.	23506136
Granuloma, Granulomatous inflammation	Altered Intercellular Communication	Histopathological examination of sea urchin granulomas shows a non-specific granulomatous inflammation, in most cases of sarcoidal type.	23506168
Inflammation, Paronychia , Keloid	Altered Intercellular Communication	Histopathological analysis of the specimen revealed the presence of irregular, thick, glassy and dense collagen of keloid and inflammation of paronychia.	23506345
Inflammation	Altered Intercellular Communication	It is implied that if an ingrown nail is not controlled, it will result in the production of chronic inflammation and tension stress, which might trigger the formation of a secondary keloid.	23506345
Inflammation, Metabolic Diseases, Atherosclerosis	Altered Intercellular Communication	As an adipocytokine, resistin has been proposed as a link between inflammation, metabolic disorder and atherosclerosis.	23506578
vascular inflammations	Altered Intercellular Communication	Oxidative stress may link multiple mechanisms of AAA including vascular inflammation and increased metalloproteinase activity.	23506637
Inflammation	Altered Intercellular Communication	Uncoupled iNOS may link oxidative stress to inflammation in AAA.	23506637
Metabolic Process, Cellular, Inflammation, Obesity, Visceral	Altered Intercellular Communication	Evidence suggests that the systemic inflammation and dysmetabolism observed in visceral obesity underpins this association.	23507222
Inflammation	Altered Intercellular Communication	There were 35 positive false zones in 20 patients (11 normal parenquima and 9 chronic inflammation).	23507291
Vascular Diseases, Inflammation	Altered Intercellular Communication	Livedoid vasculopathy is a painful, ulcerating condition of the lower legs, ankles and feet with the typical histological feature of hyalinising vascular change of dermal blood vessels with minimal inflammation.	23508660
Inflammation, Obesity	Altered Intercellular Communication	Low-grade inflammation may be involved in the changes in thyroid function and morphology in obesity.	23509206
Gingivitis	Altered Intercellular Communication	Due to irregular periodontal maintenance and poor oral hygiene, severe gingival inflammation and deep pockets persisted in the permanent dentition of the patient.	23509838
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Our findings support the hypothesis that inflammation may be a mediator in the association between maternal depression and adverse perinatal outcomes.	23509887
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	Inflammation plays an essential role in the development and progression of atherosclerotic lesions.	23511026
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Chronic inflammation plays an important role on development and progression of Type 2 diabetes (T2DM) through immunologic inflammatory mechanisms.	23511196
Inflammation, Chronic disease, Malignant Neoplasms, Cardiovascular Diseases	Altered Intercellular Communication	NLR has recently been used as a systemic inflammation marker in chronic diseases as well as a predictor of prognosis in cardiovascular diseases and malignancies.	23511196
Gastrointestinal inflammation, Burn injury	Altered Intercellular Communication	Noninvasive measurement of intestinal inflammation after burn injury.	23511286
Multiple Organ Failure, Burn Specimen Source Codes, Wounds and Injuries, Gastrointestinal inflammation	Altered Intercellular Communication	Intestinal inflammation has been linked with multiorgan failure in patients with burn and other traumatic injuries.	23511286
Gastrointestinal inflammation	Altered Intercellular Communication	We hypothesized that markers of intestinal inflammation are detectible noninvasively.	23511286
Gastrointestinal inflammation, Burn injury	Altered Intercellular Communication	Our results suggest that markers of intestinal inflammation are measurable by noninvasive means and are increased after burn injury compared with controls.	23511286
Gastrointestinal inflammation	Altered Intercellular Communication	Of note, increased IL-8 correlated with increased MPO and elastase activity, suggesting a role for neutrophil activation in burn-mediated intestinal inflammation.	23511286
Gastrointestinal inflammation, Burn injury	Altered Intercellular Communication	Thus, these inflammatory cytokine profiles may be valuable biomarkers of intestinal inflammation after burn injury.	23511286
Inflammation, Traumatic injury, Neoplasms, Congenital Rubella Syndrome	Altered Intercellular Communication	Osseous metaplasia of the eyelid is a rare entity with diverse etiologies ranging from congenital syndromes to trauma, neoplasm, and inflammation.	23511997
Inflammation	Altered Intercellular Communication	Inflammation is associated with pancreatic b-cell apoptosis and reduced insulin sensitivity.	23514733
Pain Distress Question, Inflammation, Volume Measurement	Altered Intercellular Communication	Pain, chronic relapsing inflammation and loss of volume are typical sequels of this procedure.	23515594
Inflammation, Chronic pain	Altered Intercellular Communication	At the 10-month follow-up, no inflammation was observed and chronic pain was significantly reduced.	23515594
Inflammation, Retroperitoneal fibrosis	Altered Intercellular Communication	Idiopathic retroperitoneal fibrosis (IRPF) is a rare condition of unknown aetiology characterized by chronic non-specific inflammation of the retroperitoneum.	23515600
Schistosomiasis, Infertility, Pathology	Altered Intercellular Communication	Cases of infertility in endemic areas especially when there is no supply of potable water should raise suspicion of schistosomiasis among other pathologies and possible hormonal disturbances when the testes are involved.	23515635
Inflammation	Altered Intercellular Communication	Damage-associated molecular patterns derived from mitochondria may contribute to the hemodialysis-associated inflammation.	23515931
Inflammation, Necrosis	Altered Intercellular Communication	Mitochondrial damage-associated molecular patterns (DAMPs) are released during cell necrosis or apoptosis and induce inflammation.	23515931
HD Term Type, Inflammation	Altered Intercellular Communication	The mitochondrial protein cytochrome c, as a marker of released mitochondrial DAMPs, and interleukin-6 (IL-6), as a marker of inflammation, were evaluated in HD patients.	23515931
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	The term "neurogenic appendicopathy" has been used for patients operated on for acute appendicitis with their appendices lacking signs of acute inflammation.	23516073
Shock, Inflammation, Traumatic	Altered Intercellular Communication	Heat shock protein 90 (HSP90), a broadly distributed and conserved molecule, regulates inflammation under stressful and traumatic conditions.	23516526
Inflammation, Conjunctival scar	Altered Intercellular Communication	We have investigated host microRNA (miR) expression in health (N) and disease (conjunctival scarring with (TSI) and without (TS) inflammation) to determine if these epigenetic differences are associated with pathology.	23516655
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Although modifications in bowel preparation are needed, CCE-2 might be feasible for assessing the severity of mucosal inflammation in patients with UC.	23517279
Hepatitis, Chronic, FAM126A gene	Altered Intercellular Communication	The initiation and progression of HCC is closely associated with chronic liver inflammation.	23518600
Inflammation, Pathology	Altered Intercellular Communication	The regenerating islet-derived (REG) gene family encodes a group of proteins highly expressed in several human pathologies, many of which are associated with epithelial inflammation.	23519454
Inflammatory Bowel Diseases, Colitis	Altered Intercellular Communication	REGs are highly expressed during inflammatory bowel disease (IBD)-related colonic inflammation and the in vivo expression pattern of REG1A and REG4 has been localised by using immunohistochemistry.	23519454
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Samples drawn from an IBD cohort including both inflamed and un-inflamed colonic mucosa are described, as are samples from non-IBD inflammation and healthy controls.	23519454
Uveitis	Altered Intercellular Communication	Exacerbations of intraocular inflammation with transient IOP rise at the early postoperative period occurred in six patients (23 %), and were controlled with topical corticosteroid.	23519886
Inflammation, Percutaneous transhepatic cholangiography	Altered Intercellular Communication	Our results require replication but suggest that the SERPINA5 gene, which codes for the protein C inhibitor involved in many biological processes including inflammation, may be a new susceptibility locus for PTC.	23520464
Malnutrition	Altered Intercellular Communication	Nutritional counselling sessions resulted in statistically significant post-intervention improvements in Karnofsky performance scale scores, malnutrition inflammation scores and nutritional knowledge of the patients.	23520905
Airway structure, Respiration Disorders, Bronchial Hyperreactivity, Airway Obstruction	Altered Intercellular Communication	Asthma is a common respiratory disease that is characterized by bronchial hyperresponsiveness and airway obstruction due to chronic airway inflammation.	23521807
Non-alcoholic Fatty Liver Disease, Hepatic inflammation	Altered Intercellular Communication	NAFLD is associated with insulin resistance and hepatic inflammation.	23522007
Abscess	Altered Intercellular Communication	Their abscesses, located predominantly at the paracolic gutter region (P = 0.002) were associated with fistulae (P = 0.001) and caused by transmural bowel wall inflammation.	23522395
Inflammation, Hyphema, Traumatic injury	Altered Intercellular Communication	Anterior chamber inflammation and hyphema resolved 4 weeks after the trauma.	23522587
Inflammation	Altered Intercellular Communication	Subclinical injury or inflammation may play a role as possible causative factors for the development of the pigmentation.	23522629
Inflammation	Altered Intercellular Communication	Mast cell plays a role in the initiation of inflammation and therefore in poorer healing.	23522705
ARCN1 gene, Weight decreased, Muscular Atrophy, Inflammation	Altered Intercellular Communication	Weight loss and muscle wasting are common features reported in COPD patients and they are all related with systemic inflammation.	23523152
Inflammation, Dysplasia, Ulcerative Colitis	Altered Intercellular Communication	On multivariate analysis, duration of UC (Odds ratio [OR]=1.40; 95% confidence interval [CI], 1.08-1.81; P=0.01), number of random biopsies (per increase by 8) (OR=1.64; 95% CI, 1.18-2.28; P=0.003) and target biopsies during colonoscopy (OR=9.08; 95% CI, 3.18-26.0; P<0.001) independently predicted the presence of dysplasia; endoscopic features of prior inflammation did not.	23523416
Inflammation, Dysplasia, Ulcerative Colitis	Altered Intercellular Communication	Random biopsies significantly increase the yield of dysplasia in patients with PSC and UC even in the absence of endoscopic features of prior inflammation and significantly impact clinical outcomes.	23523416
helium, Inflammation, Communicable Diseases, Hepatic Encephalopathy, Liver Cirrhosis	Altered Intercellular Communication	A causal relationship between infection, systemic inflammation, and hepatic encephalopathy (HE) has been suggested in cirrhosis.	23523580
Inflammation, Ichthyosis Bullosa of Siemens, Diverticulitis, HAMA - Gastrointestinal Symptoms	Altered Intercellular Communication	Diverticulitis appears to predispose patients to long-term gastrointestinal and emotional symptoms after resolution of inflammation; in this way, postdiverticulitis IBS is similar to postinfectious IBS.	23524129
Inflammation, Steatohepatitis	Altered Intercellular Communication	Pioglitazone was more effective than glibenclamide in improving inflammation and hepatic steatosis indices.	23524525
Inflammation, Acute Cerebrovascular Accidents	Altered Intercellular Communication	Insulin resistance (IR) has effects on inflammation and oxidative stress which have importance in acute stroke.	23524624
Inflammation, Ischemic stroke, Cerebrovascular accident	Altered Intercellular Communication	Our aim was to investigate the relationships between IR, inflammation, oxidative stress and stroke severity in acute ischemic stroke patients.	23524624
Inflammation, Cerebrovascular accident, Acute Cerebrovascular Accidents	Altered Intercellular Communication	We examined the relationships between inflammation, oxidative stress and stroke severity in 75 acute stroke patients with and without IR.	23524624
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Inflammation and oxidative stress are more evident in acute stoke patients with insulin resistance which may cause worse stroke severity.	23524624
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	In patients recovering from coronary artery bypass (CABG), little is known about the relationship of 1) immune-mediated inflammation and resultant endothelial activation, and 2) cumulative exposure to infectious pathogens (pathogen burden (PB)) implicated in coronary atherosclerosis to exhaustion.	23524631
Communicable Diseases, Inflammation	Altered Intercellular Communication	The TCAs remained on participants' ears for an average total of 122 days, without causing signs of inflammation or infection, and there were no serious device-related adverse events.	23524632
Myositis	Altered Intercellular Communication	There were obvious ultrasonographic changes of the masseter muscle in females with MPD, which might be related to the muscle inflammation.	23524800
Inflammation	Altered Intercellular Communication	Local and chronic inflammation induced by amyloid-b (Ab) plays a central role in the development of age-related macular degeneration.	23525277
Inflammation	Altered Intercellular Communication	Our findings suggest that the degradation of TJ proteins such as zonula occludens-1, occludin and F-actin by MMP-9 secreted by Ab-stimulated cells constitutes an important mechanism in the breakdown of the barrier which contributes to chronic inflammation in the retina of age-related macular degeneration.	23525277
Inflammation, Cerebral Aneurysm	Altered Intercellular Communication	Evidence that acetylsalicylic acid attenuates inflammation in the walls of human cerebral aneurysms: preliminary results.	23525414
Inflammation, Thrombosis	Altered Intercellular Communication	VCAM and tPA may have greater specificity for processes reflecting inflammation and thrombosis in the epicardial arteries, which determine recurrent coronary events.	23525424
Inflammation	Altered Intercellular Communication	Adipose tissue inflammation and perturbation of adipokine secretion may contribute to the pathogenesis of CVD.	23525430
Inflammatory Bowel Diseases, Inflammation, Acute inflammation	Altered Intercellular Communication	PGP neutralisation in DSS-treated mice showed the importance of PGP-guided neutrophilic infiltration in the intestine and indicates a vicious circle in neutrophilic inflammation in IBD.	23525573
Inflammation, Epithelioid fibrous histiocytoma, Granuloma, Foreign-Body, Granuloma	Altered Intercellular Communication	Host histopathologic responses included nodule without foreign body reaction, nodule with chronic inflammation, granuloma with epithelioid histiocytic and multinucleated giant cell reaction.	23526034
Inflammation, Asthma	Altered Intercellular Communication	Bronchial asthma is associated with increased arterial inflammation beyond that estimated by current risk stratification tools.	23526296
Asthma	Altered Intercellular Communication	Bronchial asthma is a chronic inflammatory condition associated with increased cardiovascular (CV) events.	23526296
Sepsis, Inflammation, Coinfection	Altered Intercellular Communication	Sepsis, the syndrome of microbial infection complicated by systemic inflammation, is associated with significant morbidity and mortality.	23526732
Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	PET/CT visualises infection, inflammation and malignancy, all of which may cause elevated ESR.	23527049
Inflammation, Thrombosis	Altered Intercellular Communication	Thrombospondin-1 and -2 (TSP-1 and -2) have been implicated in the regulation of angiogenesis, thrombosis, and inflammation, which are believed to be critical in the pathogenesis of cardiovascular events.	23528028
Hirschsprung Disease, Inappropriate ADH Syndrome	Altered Intercellular Communication	The patient developed Hirschsprung disease and the syndrome of inappropriate antidiuretic hormone secretion (SIADH), which had not previously been described in TUBA1A mutation-associated disease.	23528852
Graft-vs-Host Disease, Inflammatory disease of mucous membrane	Altered Intercellular Communication	S100A9-short was detected in 20 patients with GVHD, in 9 patients without GVHD, and in 8 healthy volunteers (P = .01) Further studies are needed to clarify the role of these proteins as a marker of GVHD or as an index of mucosal inflammation.	23529013
Inflammation, Fibrosis Assessment, Fatty degeneration, Fatty Liver Disease	Altered Intercellular Communication	On liver biopsy specimens, performed in each patient, the NASH score, representing the sum of fibrosis, steatosis, lobular inflammation and ballooning, was calculated.	23529326
Pulmonary Emphysema, Centriacinar Emphysema, Pneumonitis	Altered Intercellular Communication	In vivo quantification of pulmonary inflammation in relation to emphysema severity via partial volume corrected (18)F-FDG-PET using computer-assisted analysis of diagnostic chest CT. Our aim was to quantify the degree of pulmonary inflammation associated with centrilobular emphysema using fluoro-18-2-fluoro-2-deoxy-D-glucose positron emission tomography ((18)F-FDG-PET) and diagnostic unenhanced computed tomography (CT) based image segmentation and partial volume correction.	23529388
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	These results support the notion that pulmonary inflammation plays an important role in the pathophysiology of emphysema.	23529388
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	This novel image analysis approach has great potential for practical, accurate, and precise combined structural-functional PET quantification of pulmonary inflammation in patients with emphysema or other pulmonary conditions, although further validation and refinement will be required.	23529388
Inflammation	Altered Intercellular Communication	NfL levels correlated with the Expanded Disability Status Scale (EDSS) score in patients with relapsing disease (r(s) = 0.31; p = 0.002), spinal cord relapses and with CSF markers of acute inflammation.	23529999
Inflammation, Pericardial Effusion, CTCAE, Diarrhea, Early-onset, Abdominal Pain	Altered Intercellular Communication	Here, we report the case of an 11-month-old boy with early-onset, recurrent episodes of unprovoked fever lasting 7 to 10 days and associated with pericardial effusion, abdominal pain, diarrhea, and inflammation.	23530176
Renal Insufficiency, Inflammation	Altered Intercellular Communication	Similarly to RDW, impaired renal function is also associated with inflammation and protein-energy wasting.	23530521
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The results were consistent in subgroups of patients with different levels of haemoglobin, chronic kidney disease status and various markers of inflammation and iron status.	23530521
Inflammation, Comorbidity	Altered Intercellular Communication	Lower eGFR is associated with higher RDW, independent of comorbidity, iron deficiency, inflammation and nutritional status in kidney transplant recipients.	23530521
Inflammation, Secondary malignant neoplasm of lung, Breast Carcinoma, Obesity	Altered Intercellular Communication	Increased levels of urinary PGE-M, a biomarker of inflammation, occur in association with obesity, aging, and lung metastases in patients with breast cancer.	23531446
Inflammation, Cardiac sarcoidosis	Altered Intercellular Communication	The PET/CT scan was performed to assess disease activity of cardiac sarcoidosis, and no active cardiac inflammation was detected.	23531736
Inflammation, Diabetes Mellitus, Cardiovascular Diseases	Altered Intercellular Communication	Omentin-1 is an adipokine implicated in diabetes, inflammation, and cardiovascular disease.	23532633
Airway structure	Altered Intercellular Communication	Measurement of the fraction of exhaled nitric oxide (FeNO) is a useful test to diagnose and/or monitor eosinophilic airway inflammation.	23532936
Immunocompromised Host	Altered Intercellular Communication	Listeria monocytogenes is a rare but relevant cause of systemic inflammations in immunocompromised patients.	23533043
Inflammation, Periodontitis, Chronic Kidney Diseases	Altered Intercellular Communication	Periodontitis is an important source of systemic inflammation in CKD patients.	23534529
Aneuploidy, Neoplasms	Altered Intercellular Communication	High S-phase fraction and aneuploidy were associated with tumours with higher grade of differentiation, greater size and negative hormonal receptors.	23534591
Azoospermia	Altered Intercellular Communication	Herein, we report an interesting case of a patient who spontaneously recovered from azoospermia due to a traffic injury and present in detail the results of the hormonal examination and semen analysis.	23534890
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	In this way, we can not only predict the occurrence of MetS with a relatively low-cost and routine lab test, but also can understand more about the relationships between low grade inflammation and MetS.	23534910
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	In the absence of an interrelationship between vascular function and thermoregulation, the contribution of inflammation to BTV was increased in subjects with diabetes (BTV, 0.59+-0.21degC for C-reactive protein [CRP] <0.08 mg/dl vs. 0.79+-0.28degC for CRP >0.08 mg/dl, P=0.014).	23535220
Endocrine System Diseases, Traumatic injury	Altered Intercellular Communication	Hormonal disturbances, trauma, immunosuppression, actinic damages and radiotherapy have been suggested as possible etiologic factors; however, the exact pathophysiology remains unclear.	23535945
Arterial Stiffness, Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Inflammation does not influence arterial stiffness and pulse-wave velocity in patients with coronary artery disease.	23535991
Inflammation	Altered Intercellular Communication	Developing evidence suggests that inflammation may be another risk factor.	23535991
Inflammation, Liver carcinoma, Adenocarcinoma of pancreas	Altered Intercellular Communication	It has been shown that MPV level is a sign of inflammation in hepatocellular carcinoma and pancreatic adenocarcinoma.	23537073
Inflammation, Diabetes Mellitus, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Magnesium influences endothelial function, inflammation, blood pressure, and diabetes, but a direct relation with coronary heart disease (CHD) risk has not been established.	23537810
Sepsis, Inflammation	Altered Intercellular Communication	A 9-month-old infant presented with fatal pneumococcal sepsis and attenuated inflammation indices.	23538514
Inflammation, Cystic Fibrosis	Altered Intercellular Communication	Cigarette smoke and smoking-induced inflammation decrease cystic fibrosis transmembrane conductance regulator (CFTR) activity and mucociliary transport in the nasal airway and cultured bronchial epithelial cells.	23538783
Inflammation	Altered Intercellular Communication	The NLRs indicative of the balance between host immunity and cancer-related inflammation were consistently lower in the PFS-long group than in the PFS-short group, suggesting that lower NLR is associated with better clinical response.	23539200
Inflammation, CEREBRAL AMYLOID ANGIOPATHY, ITM2B-RELATED, 1, HIV Infections	Altered Intercellular Communication	No differences in CRF2 expression profile were observed in distal/sigmoid intestinal biopsies from HIV infection and FBD patients, showing no signs of inflammation.	23539366
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The down-regulation of the CRF2 receptor in the distal/sigmoid biopsies of UC patients is indicative of change in CRF2 signalling associated with the process of inflammation.	23539366
Inflammation, Colonic Diverticulitis, Diverticulitis	Altered Intercellular Communication	Detection of endoscopic and histological inflammation after an attack of colonic diverticulitis is associated with higher diverticulitis recurrence.	23539385
Inflammation, Diverticulitis	Altered Intercellular Communication	The aim of our study was to investigate the role of endoscopic and histological inflammation as predictors for the recurrence of diverticulitis.	23539385
Inflammation	Altered Intercellular Communication	At the end of the follow-up period, endoscopic inflammation was still detected in 31 (27.67%) patients, and active histological inflammation in 41 patients (36.6 %).	23539385
Inflammation, Diverticulitis	Altered Intercellular Communication	Only detection of endoscopic and of histological inflammation during the follow-up was a predictor of diverticulitis recurrence (Log rank test, p = 0.0004).	23539385
Inflammation, Diverticulitis	Altered Intercellular Communication	Detection of endoscopic and histological inflammation after attack of AUD was identified as a predictor of diverticulitis recurrence.	23539385
Inflammation	Altered Intercellular Communication	Inhibition of release of inflammatory mediators by p38 inhibitors may be a useful treatment for chronic inflammation of the airways thought to underlie the pathogenesis of the disease.	23539534
Inflammation, Pain, Postoperative, Microorganism	Altered Intercellular Communication	Acute periapical inflammation is the most common cause of postoperative pain developing as a result of mechanical, chemical and/or microbial injury of periapical tissue.	23539905
Inflammation, Hemorrhage, Carotid Stenosis	Altered Intercellular Communication	Both magnetic resonance detected carotid plaque hemorrhage (MRI PH(+)) and features of inflammation are associated with increased risk of cerebrovascular events in patients with carotid stenosis.	23540670
Inflammation, Dental Plaque	Altered Intercellular Communication	To further assess the potential of MRI PH as a biomarker for complicated carotid plaque, its relationship with inflammation needs to be assessed.	23540670
Vasculitis, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	The densities of tumor-associated CD66b(+) neutrophils and CD163(+) macrophages in NSCLC were correlated with adverse prognostic factors and systemic blood inflammation markers, but not directly correlated with RFS or OS.	23540719
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Further research of chronic inflammation in NSCLC is warranted.	23540719
Inflammation, hepcidin	Altered Intercellular Communication	Inflammation plays an important role in the regulation of hepcidin expression.	23540794
Inflammation, Metaplasia, Urothelial Hyperplasia	Altered Intercellular Communication	Nonneoplastic processes were found in 70 of 108 patients (65%), including inflammation, metaplasia, and urothelial hyperplasia, with or without atypia/dysplasia.	23540860
Inflammation, Dysplasia, Metaplasia, Diverticulum	Altered Intercellular Communication	Inflammation, metaplasia, and dysplasia are commonly seen in vesical diverticula.	23540860
Inflammation, Exanthema, Communicable Diseases, Leukopenia, Thrombocytopenia	Altered Intercellular Communication	Mucosal inflammation, thrombocytopenia, neutropenia, infection, and skin rash were more frequent when everolimus was added to paclitaxel.	23541564
Hyperparathyroidism, Primary, Osteopenia	Altered Intercellular Communication	In primary hyperparathyroidism (PHPT), protracted elevation of serum parathyroid hormone (PTH) is held to be associated with cortical, but not trabecular, bone loss.	23541782
Inflammation, Gastrointestinal mucositis	Altered Intercellular Communication	Data comparing basal cells from buccal vs. gingival mucosa identified differential gene expression of host responses in relation to pathways relevant to oral mucositis pathogenesis, including responses to cancer-associated inflammation.	23541936
Inflammation	Altered Intercellular Communication	OxPL circulate in plasma, are transported by Lp(a), and deposit in the vascular wall and induce local inflammation.	23541965
Inflammation, Fibrosis Assessment, Renal cyst, Chronic Kidney Diseases, Enlarged kidney	Altered Intercellular Communication	The treatment with tolcapone markedly attenuated the loss of renal function, inhibited renal enlargement, shifted the size distribution of renal cysts and retarded cell proliferation, apoptosis, inflammation and fibrosis development in affected (cy/+) male and female PKD/Mhm and PKD/US rats.	23543593
Autoimmune Diseases, Inflammation, Frontotemporal dementia	Altered Intercellular Communication	Given the association between systemic inflammation and other neurodegenerative processes, links between autoimmunity and FTD need to be explored.	23543794
Inflammation, Disease, GRN wt Allele	Altered Intercellular Communication	These findings suggest a unique pattern of systemic inflammation in svPPA and PGRN and open new research avenues for understanding and treating disorders associated with underlying transactive response DNA-binding protein 43 aggregation.	23543794
Aneuploidy, Inflammation, Dysplasia	Altered Intercellular Communication	Neither a correlation between aneuploidy and inflammation (p = 0.916) nor between aneuploidy and dysplastic lesions (p = 0.159) could be observed.	23544594
Aneuploidy, Inflammation, Dysplasia	Altered Intercellular Communication	Furthermore, aneuploidy seems to be irrespective of inflammation or dysplasia.	23544594
Aneurysm, carotid disease, Carotid Artery Diseases, Intracranial Aneurysm	Altered Intercellular Communication	Although it is hypothesized that inflammatory signals and/or hemodynamic stress resulting from carotid disease increase the risk of aneurysm formation and growth, a relationship between intracranial aneurysms and extracranial carotid artery disease (ECAD) has not been explored.	23545151
Inflammation	Altered Intercellular Communication	Phospholipid transfer protein (PLTP) modulates lipoprotein metabolism and plays an important role in inflammation and oxidative stress.	23545183
Inflammation	Altered Intercellular Communication	Inflammation has also been linked with development of cardiovascular events (CVE) in T2DM.	23546612
Aggressive course, Inflammation	Altered Intercellular Communication	Intratumoral inflammation is associated with more aggressive prostate cancer.	23546767
Inflammation, Prostate carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Inflammation may play a role in the development and progression of many cancers, including prostate cancer.	23546767
Aggressive course, Inflammation, Prostate carcinoma	Altered Intercellular Communication	We sought to test whether histological inflammation within prostate cancer was associated with more aggressive disease.	23546767
Inflammation, Neoplasms	Altered Intercellular Communication	The area with the greatest tumor burden was scored in a blinded manner for the degree of inflammation: absent, mild, or marked.	23546767
Inflammation	Altered Intercellular Communication	No inflammation was found in 49 men (17%), while 153 (53%) and 85 (30%) had mild and marked inflammation.	23546767
Inflammation	Altered Intercellular Communication	On multivariate analysis, more inflammation was associated with greater risk of positive margins, capsular penetration, and seminal vesicle invasion (all p < 0.05).	23546767
Inflammation	Altered Intercellular Communication	Marked inflammation was associated with increased PSA recurrence risk when adjusting for preoperative features only (HR 2.08, 95% CI 1.02-4.24), but not after adjusting for pathologic features.	23546767
Aggressive course, Inflammation, Prostate carcinoma	Altered Intercellular Communication	Inflammation within prostate cancer was associated with more advanced disease, although it is unclear whether aggressive disease caused increased inflammation or inflammation caused aggressive disease.	23546767
ARCN1 gene, Inflammation, Abnormal renal function	Altered Intercellular Communication	We tested the hypothesis that COPD patients, even in those with mild-to-moderate airflow obstruction, are affected by systemic inflammation associated with abnormal renal functional reserve.	23547633
Renal Insufficiency, ARCN1 gene, Airway Obstruction, Inflammation	Altered Intercellular Communication	A greater impairment in renal functional reserve of COPD patients was correlated with more severe airway obstruction and inflammation.	23547633
Inflammation, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	In 3/5 with CMR positive for myocarditis, coronary arteries were normal, but endomyocardial biopsy revealed inflammation with normal PCR.	23547732
Anemia	Altered Intercellular Communication	The high prevalence of H. pylori exposure, together with dietary iron adequacy, suggests an inflammation-driven iron deficiency and mild anemia.	23547888
Inflammation, Asthma	Altered Intercellular Communication	Eosinophilic inflammation of the small airways is a key process in asthma that often smolders in treated patients.	23548532
Colitis, Short Bowel Syndrome	Altered Intercellular Communication	Gut microbial diversity is reduced and is associated with colonic inflammation in a piglet model of short bowel syndrome.	23549027
antimony, Inflammatory disease of mucous membrane, Short Bowel Syndrome, Malabsorption Syndrome, Bacterial resistance, Intestines, Small	Altered Intercellular Communication	Following small bowel resection (SBR), the luminal environment is altered, which contributes to clinical manifestations of short bowel syndrome (SBS) including malabsorption, mucosal inflammation and bacterial overgrowth.	23549027
Inflammation	Altered Intercellular Communication	This decrease in diversity was associated with an increase in colonic inflammation six weeks post-surgery.	23549027
Inflammatory disease of mucous membrane	Altered Intercellular Communication	SBR significantly decreased the diversity of the colonic microbiota and this was associated with an increase in colonic mucosal inflammation.	23549027
Inflammation, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Necrotizing vasculitis	Altered Intercellular Communication	Anti-neutrophil cytoplasmic antibody-associated (ANCA-associated) small vessel necrotizing vasculitis is caused by immune-mediated inflammation of the vessel wall and is diagnosed in some cases by the presence of myeloperoxidase-specific antibodies (MPO-ANCA).	23549081
Inflammation, Postoperative Complications, Glaucoma, CTCAE	Altered Intercellular Communication	Outcome measures include visual acuity, intraocular pressure, need for glaucoma surgery, postoperative complications, and control of inflammation.	23549097
airway disease, Bronchial Hyperreactivity, Airway structure	Altered Intercellular Communication	Asthma is a chronic airway disease characterized by airway inflammation, bronchial hyperresponsiveness and airflow obstruction.	23550166
Lipodystrophy, Inflammation	Altered Intercellular Communication	Lipodystrophy and inflammation predict later grip strength in HIV-infected men: the MACS Body Composition substudy.	23550976
Inflammation	Altered Intercellular Communication	Body fat changes in HIV-infected persons are associated with increased systemic inflammation and increased mortality.	23550976
Lipodystrophy, Inflammation	Altered Intercellular Communication	Inflammation, lower LBM, and lipodystrophy in HIV-infected men were associated with lower subsequent grip strength.	23550976
Inflammation	Altered Intercellular Communication	These findings suggest that inflammation may contribute to declines in functional performance, independent of age.	23550976
Limbic Encephalitis, Encephalitis, Inflammation, Autoimmune Diseases	Altered Intercellular Communication	Autoimmune epilepsy was suspected clinically when there was any of the following: (1) recognizable syndromes such as NMDAR encephalitis or limbic encephalitis, (2) evidence of CNS inflammation in cerebrospinal fluid or on magnetic resonance imaging (MRI), (3) the presence of other autoimmune diseases, or (4) positive response to immunotherapy.	23551014
Vasomotor instability, Neurogenic Inflammation, Allergic	Altered Intercellular Communication	Possible mechanisms include odor induced, emotional change, vasomotor instability, trigeminal-induced neurogenic inflammation, and allergic response.	23551212
Inflammation, Pruritus	Altered Intercellular Communication	The high prevalence of pruritus in elderly patients is attributed in part to the decline in the normal physiology of the advanced aging skin, and reflects poor hydration, impaired skin barrier, and altered neural function, all ultimately contributing to inflammation and pruritus.	23551366
vascular inflammations	Altered Intercellular Communication	Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an independent risk factor for CVD and has been proposed as a marker of vascular inflammation.	23551952
Granulomatous inflammation, Scleritis, Necrosis	Altered Intercellular Communication	The areas of scleritis showed complete disruption of sclera collagen, necrosis and infiltration with neutrophils, macrophages, lymphocytes, and granulomatous inflammation with MNGC.	23552359
Granulomatous inflammation, Scleritis	Altered Intercellular Communication	Granulomatous inflammation in ASK is probably responsible for the continuance and progression of the scleritis and management protocols should include immunosuppressive agents alongside amoebicidal drugs.	23552359
Follicle, Alopecia, CTCAE, Perifolliculitis	Altered Intercellular Communication	Biopsies revealed perifollicular lymphocytic inflammation and evidence of follicular injury but normal hair density, consistent with a nonscarring alopecia.	23552567
Inflammation, Alopecia, CTCAE	Altered Intercellular Communication	Nilotinib therapy may induce perifollicular inflammation and widespread persistent alopecia.	23552567
Inflammation, Fibrosis Assessment, Actinomyces israelii (bacteria), Squamous metaplasia	Altered Intercellular Communication	Histopathologic examination demonstrated chronic inflammation in 11 eyes (36.7%), fibrosis in 7 eyes (23.3%), chronic inflammation and fibrosis in 4 eyes (13.3%), squamous metaplasia in 3 eyes (10%), normal conjunctival mucosa in 3 eyes (10%), and Actinomyces israelii canaliculitis in 2 eyes (6.7%).	23552606
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Nearly all histopathologic specimens revealed findings consistent with inflammation, fibrosis, or both.	23552606
Inflammation, Stenosis of lacrimal punctum	Altered Intercellular Communication	These findings provide evidence to support the hypothesis that the many etiologic causes of punctal stenosis are linked by a common pathophysiologic mechanism involving inflammation.	23552606
allergic inflammation	Altered Intercellular Communication	An allergic inflammation was suspected to have occurred in the spermatic cord.	23552761
Inflammation, Neoplasms	Altered Intercellular Communication	A 51-year-old woman presented with a non-specific tumor of the iris and intraocular inflammation of the left eye.	23552857
Inflammation, Primary malignant neoplasm, Diabetes Mellitus, Cardiovascular Diseases	Altered Intercellular Communication	A high intake of trans fatty acids decreases HDL cholesterol and is associated with increased LDL cholesterol, inflammation, diabetes, cancer, and mortality from cardiovascular disease.	23553155
Inflammation, Myositis, CTCAE 5.0	Altered Intercellular Communication	Some PBC cases are complicated by myositis, which is difficult to confirm due to minimal histological evidence of inflammation in limb muscles.	23553600
Inflammation, Vascular Diseases, Atherosclerosis	Altered Intercellular Communication	Elevated rho-kinase activity as a marker indicating atherosclerosis and inflammation burden in polyvascular disease patients with concomitant coronary and peripheral arterial disease.	23553913
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The highest values of IL-6 were obtained in early cancer (more than 8-fold increase), which seems to confirm the presence of acute inflammation.	23554823
Inflammation	Altered Intercellular Communication	Residual inflammation at ICU discharge may have impact upon long-term mortality.	23555017
Communicable Diseases, Inflammation, septic	Altered Intercellular Communication	Since infection is a potent trigger of inflammation, we hypothesized that CRP levels at discharge would correlate with long-term mortality in septic patients and that the CRP/albumin ratio would be a better marker of prognosis than CRP alone.	23555017
Inflammation, Neoplasms	Altered Intercellular Communication	These findings implicate CAFs as an important target for blocking inflammation in the tumor microenvironment and reducing tumor growth.	23555186
Arthralgia, Inflammation, Chikungunya Fever	Altered Intercellular Communication	This study demonstrates that chronic arthralgia is a frequent complication of acute Chikungunya disease and suggests that it results from a local rather than systemic inflammation.	23556021
Hemorrhage, Hyponatremia	Altered Intercellular Communication	We describe herein the case of a 68-year-old female presenting with a bleeding rectal mass involving the anal canal, which case was associated with hyponatremia due to inappropriate serum levels of antidiuretic hormone.	23556266
Inflammation, Liver Cirrhosis, FAM126A gene	Altered Intercellular Communication	Inflammation in background cirrhosis evokes malignant progression in HCC development from HCV-associated liver cirrhosis.	23556482
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	It is accepted that inflammation promotes malignant progression in the development of cancers.	23556482
Inflammation, Necrosis	Altered Intercellular Communication	To evaluate the inflammation, piece meal necrosis, intra lobular cellular degeneration and focal necrosis, portal cellular inflammation (0-4, each) were estimated.	23556482
Inflammation, Cirrhotic, FAM126A gene	Altered Intercellular Communication	Inflammation in the background non-cancerous cirrhotic portion would evoke malignant progression in HCC development from HCV-associated LC.	23556482
methyldopa, Inflammation	Altered Intercellular Communication	Chronic inflammation is implicated in the pathogenesis of AMD.	23557734
Inflammation	Altered Intercellular Communication	The source of chronic inflammation is often attributed to the progressive activation of immune cells over time.	23557734
Inflammation	Altered Intercellular Communication	However, recent studies have shown that senescent cells can alter tissue microenvironment via secretion of growth factors, proteases, and inflammatory cytokines and might be an additional source of chronic inflammation.	23557734
methyldopa, Inflammation	Altered Intercellular Communication	We hypothesized that altered secretory pattern in Ab-induced senescent RPE cells may contribute to compromised RPE barrier integrity and chronic inflammation in AMD.	23557734
methyldopa, Inflammation	Altered Intercellular Communication	The altered secretory phenotype of senescent RPE cells may contribute to age-related inflammation in AMD.	23557734
Mood Disorders	Altered Intercellular Communication	Alterations in mu-opioid neurotransmission may underlie limbic system activity and mood disorders in IR-PCOS.	23557757
Inflammation, Meningoencephalitis, Meningitis	Altered Intercellular Communication	Of 117 cases in the database with a diagnosis of meningitis or meningoencephalitis, 39 had neutrophilic inflammation in the meninges.	23558577
Arthritis	Altered Intercellular Communication	Relaxin hormone may play a role in the development of arthritis at the thumb CMC joint.	23559157
Communicable Diseases, Inflammation	Altered Intercellular Communication	No evidence of infection or inflammation was detected.	23559361
BDI - Functional Impairment, Inflammation	Altered Intercellular Communication	Association of functional impairment with inflammation and immune activation in HIV type 1-infected adults receiving effective antiretroviral therapy.	23559466
BDI - Functional Impairment, Inflammation, HIV-1	Altered Intercellular Communication	The relationships of inflammation, immune activation, and immunosenescence markers with functional impairment in aging human immunodeficiency virus type 1 (HIV-1)-infected persons are unknown.	23559466
Inflammation, Thrombosis	Altered Intercellular Communication	The exact underlying mechanisms responsible for AVF failure are unknown but processes like proliferation, inflammation, vascular remodeling, and thrombosis are thought to be involved.	23559680
Inflammation, Mediastinal Emphysema	Altered Intercellular Communication	Initial chest computed tomography (CT) showed pneumomediastinum and local inflammation, but follow-up CT showed improved pneumomediastinum.	23560657
Inflammation, Malnutrition	Altered Intercellular Communication	In conclusion, these results suggest that the earthquake increased the incidence of HF in association with high blood pressure, interruption of drugs, inflammation, malnutrition, and fluid retention.	23561586
Vitreous inflammatory cells	Altered Intercellular Communication	Seven patients had anterior chamber and eight had vitreous inflammation.	23561607
Inflammation, Depressed mood	Altered Intercellular Communication	Despite immune suppression, PMNL transmigration was increased and p38 phosphorylation capacity was not depressed, which may contribute to end organ inflammation and dysfunction.	23561969
Inflammation, GDC Disease Response Terminology, Diabetes Mellitus	Altered Intercellular Communication	These genes are still of particular interest because they are involved in insulin regulation, inflammation, lipid signaling and apoptosis pathways, all of which are possibly involved with DR. Our finding nominates possible novel loci as potential DR susceptibility genes in the Chinese that are independent of the level of HbA1c and duration of diabetes and may provide insight into the pathophysiology of DR.	23562823
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Simvastatin suppresses vascular inflammation and atherosclerosis in ApoE(-/-) mice by downregulating the HMGB1-RAGE axis.	23564080
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	High mobility group box protein 1 (HMGB1) and receptor for the advanced glycation end product (RAGE) play pivotal roles in vascular inflammation and atherosclerosis.	23564080
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	The aim of this study was to determine whether the HMGB1-RAGE axis was involved in the actions of simvastatin on vascular inflammation and atherosclerosis in ApoE(-/-) mice.	23564080
Atherosclerosis	Altered Intercellular Communication	Vehicle-treated ApoE(-/-) mice exhibited significant increases in aortic inflammation and atherosclerosis as well as enhanced expression of HMGB1, RAGE, VCAM-1, and MCP-1 in aortic tissues as compared to the wild-type mice.	23564080
vascular inflammations, Atherosclerotic lesion	Altered Intercellular Communication	Administration with simvastatin in ApoE(-/-) mice markedly attenuated the vascular inflammation and atherosclerotic lesion area, and decreased the aortic expression of HMGB1, RAGE, VCAM-1, and MCP-1.	23564080
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Simvastatin inhibits vascular inflammation and atherosclerosis in ApoE(-/-) mice, which may be mediated through downregulation of the HMGB1-RAGE axis.	23564080
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Interleukin (IL)-17A, the signature cytokine of Th17 cells, was recently described to promote inflammation and fibrosis within the liver.	23564624
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	These data should prompt further studies investigating the link between pathogen responses, inflammation, and fibrosis in patients with PSC.	23564624
Prostate, Neoplasms	Altered Intercellular Communication	Conditional transgenic expression of PIM1 kinase in prostate induces inflammation-dependent neoplasia.	23565217
Lesion, Inflammation	Altered Intercellular Communication	Analysis of senescence induced in these prostatic lesions showed that the lesions induced in the presence of inflammation exhibited different behavior than those induced in the absence of inflammation.	23565217
Inflammation, vinyltriethoxysilane	Altered Intercellular Communication	Statins reduce levels of inflammation biomarkers; however, the mechanism for the reduction in VTE risk is unknown.	23565981
Fibrous, Obstruction, Inflammation	Altered Intercellular Communication	There were various sites of obstruction and various conditions such as oedematous thickening of the mucosa of the lacrimal duct and fibrous tissue because of chronic inflammation.	23566023
Inflammation, Gilbert Disease (disorder)	Altered Intercellular Communication	Protection from age-related increase in lipid biomarkers and inflammation contributes to cardiovascular protection in Gilbert's syndrome.	23566065
Sepsis, Inflammation, Traumatic, Cerebrovascular accident	Altered Intercellular Communication	Patients treated in one of the Intensive Care Units (ICU) at the University Hospital Bonn diagnosed with sepsis or systemic inflammatory response syndrome (n = 12) and patients who were treated due to traumatic brain injury, or stroke without clinical or laboratory signs of sepsis or major inflammation (n = 22) were included.	23566119
Left Ventricular Function	Altered Intercellular Communication	The influence of atorvastatin on parameters of inflammation left ventricular function, hospitalizations and mortality in patients with dilated cardiomyopathy--5-year follow-up.	23566246
Acute Kidney Injury, CTCAE, Inflammation, Anemia	Altered Intercellular Communication	Serum Soluble-Fas, Inflammation, and Anemia in Acute Kidney Injury.	23566289
Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	In multivariate analysis, after adjusting for markers of inflammation and iron stores, only serum sFas levels (P = 0.03) correlated negatively with Hb concentration in the AKI group.	23566289
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Immune activation and inflammation represent critical factors in the pathogenesis of Alzheimer's disease (AD) and are associated with increased blood concentrations of markers like neopterin and the kynurenine to tryptophan ratio (Kyn/Trp).	23566485
Behavioral and psychological symptoms of dementia	Altered Intercellular Communication	In chronic inflammatory conditions, also increased serum phenylalanine concentrations and phenylalanine to tyrosine ratios (Phe/Tyr) were reported and could relate to neuropsychiatric symptoms.	23566485
Inflammation, Neoplasms	Altered Intercellular Communication	These results suggest that EGFR-TKIs may suppress systemic inflammation and promote tumor shrinkage.	23566546
Inflammation, Hypertension, CTCAE, Obesity	Altered Intercellular Communication	Vitamin D (VD) may be implicated in obesity and its complications such as insulin resistance, hypertension, and low-grade inflammation.	23566943
Inflammation, Chronic Obstructive Airway Disease, Hypertension, CTCAE	Altered Intercellular Communication	[Biomarkers of systemic inflammation, oxidative stress and their interactions in patients with combined flow of chronic obstructive pulmonary disease and arterial hypertension].	23567304
Inflammation	Altered Intercellular Communication	Significant correlations between biomarkers of systemic inflammation and oxidative stress were found.	23567304
Inflammation, Aortic Valve Stenosis, Hypertrophic Cardiomyopathy	Altered Intercellular Communication	Myocardial hypertrophy is associated with inflammation and activation of endocannabinoid system in patients with aortic valve stenosis.	23567807
Inflammation, Fibrosis Assessment, Traumatic injury	Altered Intercellular Communication	Endocannabinoids and their receptors have been associated with cardiac adaptation to injury, inflammation and fibrosis.	23567807
Inflammation	Altered Intercellular Communication	Taken together, these results suggest a prominent role for MCPIP1 in the control of inflammation and immune homeostasis.	23567898
Acute inflammation, Inflammatory disease of mucous membrane, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Histopathological examination of the lesion revealed chronic mucosal inflammation with acute inflammation and H. pylori infection.	23569348
Acute inflammation, Inflammatory disease of mucous membrane, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Histopathological examination revealed chronic mucosal inflammation with acute inflammation and a very small amount of H. pylori infection.	23569348
Inflammation	Altered Intercellular Communication	H. pylori-associated severe inflammation can lead to neoplastic changes in histiocytes.	23569348
Steatohepatitis, Fibrosis Assessment, Fatty degeneration, Inflammation	Altered Intercellular Communication	The severity of hepatic steatosis increased in patients with hepatic steatosis, compared to those without steatosis (P < 0.01), but the severities of inflammation and fibrosis in the non-hepatic steatosis group were dramatically higher than those in the hepatic steatosis group (P < 0.01).	23569427
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis, comprise a group of diseases characterized by inflammation of the wall of small vessels.	23570759
Inflammation, Nasopharyngeal carcinoma	Altered Intercellular Communication	Chronic inflammation plays an important role in nasopharyngeal carcinoma (NPC) development and progression.	23571148
Degenerative polyarthritis, Inflammation, Knee joint	Altered Intercellular Communication	Standardized CDUS examinations were performed in 111 knee joints of 106 patients (70 women and 36 men) presenting with severe OA (n = 72) or confirmed IA (n = 39) of one or both knee joints to determine the degree of synovial inflammation in a semiquantitative fashion.	23571653
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	To improve the clinical utility of MPV and role of inflammation in the pathogenesis of atrial fibrillation, further studies are needed to be carried out.	23571683
Inflammation, Thrombosis	Altered Intercellular Communication	For example, they become procoagulant when undergoing apoptosis and may contribute to thrombosis or inflammation.	23571768
Inflammation, Psoriasis	Altered Intercellular Communication	Chemokines may contribute to the systemic inflammation that is linked to the increased risk of co-morbidities in patients with psoriasis.	23571825
Inflammation, Psoriasis	Altered Intercellular Communication	The sustained high expression of inflammatory chemokines is a potential link to systemic inflammation in psoriasis.	23571825
HD Term Type, Inflammation, Cardiovascular system	Altered Intercellular Communication	Chronic inflammation, as measured by higher serum IL-6 levels, in combination with high basal NO is associated with worse clinical outcomes in terms of all-cause and cardiovascular death in clinically stable prevalent HD patients.	23572414
Impaired cognition	Altered Intercellular Communication	This finding seems to suggest in humans the observation made in animal models that not only b-amyloid protein, but also tau and phospho-tau proteins, are involved in the aberrant regulation of neural transmission possibly contributing to EEG deterioration, cognitive decline and worse prognosis.	23574167
Inflammation, PEELING SKIN SYNDROME	Altered Intercellular Communication	Taken together, our findings suggest that these lower levels of SSA-specific memory B cells in PB and absence of SSA-specific memory B cells in SG of pSS patients could result from activation of these cells into plasma cells at the site of inflammation.	23574319
Inflammation, Obesity	Altered Intercellular Communication	Obstructed subjects exhibited greater evidence of systemic inflammation, abnormal glucose homeostasis, and central obesity than controls.	23574362
Inflammation, Asthma	Altered Intercellular Communication	Individuals with coexisting asthma and fixed airflow obstruction have heightened systemic inflammation.	23574362
Inflammation, Complex Regional Pain Syndromes, Pain Distress Question	Altered Intercellular Communication	Exaggerated inflammation and oxidative stress are involved in the pathogenesis of Complex Regional Pain Syndrome (CRPS).	23574939
Retinal Detachment, Inflammation	Altered Intercellular Communication	Chronic recurrent presentation was significantly associated with more severe anterior segment inflammation at presentation as indicated by presence of mutton-fat keratic precipitates, anterior chamber reaction >=2+, iris nodules and posterior synechiae (p < 0.001 for all comparisons), less exudative retinal detachment at presentation (p < 0.001), more complications during the follow-up period (p < 0.001) and a worse visual outcome (p < 0.001).	23575246
Retinal Detachment, Inflammation, Complication Aspects	Altered Intercellular Communication	Chronic recurrent VKH disease is significantly associated with more severe anterior segment inflammation and less exudative retinal detachment at presentation, more ocular complications and a worse visual outcome than initial-onset acute VKH disease.	23575246
Pleurisy, Pleural effusion disorder	Altered Intercellular Communication	CA-125 levels in benign pleural effusions may not be influenced by pleural inflammation or hydrostatic or oncotic pressure changes.	23575338
Inflammation, Tissue Adhesions	Altered Intercellular Communication	After conversion of the first case to laparoscopy because of severe inflammation and adhesions, the following 14 consecutive transgastric procedures were completed.	23575528
Hyperglycemia, Electrocardiogram: myocardial infarction (finding), Inflammation	Altered Intercellular Communication	Acute hyperglycaemia and inflammation in patients with ST segment elevation myocardial infarction.	23575781
Hyperglycemia, Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Acute hyperglycaemia in patients with ACS may be associated with increased systemic inflammation.	23575781
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Leukocytes are the major cellular mediators of inflammation and their elevated count is associated with higher CV event rate in ACS patients.	23575781
Intestinal Diseases, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Patients with enteropathy or intestinal mucosal inflammation (associated with dysmotility or short bowel) were significantly shorter than patients without enteropathy (P = 0.007).	23576042
Intestinal Diseases, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Children with enteropathy or intestinal mucosal inflammation are at greatest risk of growth failure.	23576042
Fibrosis Assessment, Myocarditis	Altered Intercellular Communication	Recently, galectin-3 emerged as a marker of myocardial inflammation and fibrosis which may influence LV remodelling after surgery.	23576289
Toxoplasma, Vitreous inflammatory cells	Altered Intercellular Communication	The absence of vitreous inflammation: one more challenge in diagnosing toxoplasma papillitis.	23576658
Inflammation, Precocious atherosclerosis, Lupus Erythematosus, Systemic	Altered Intercellular Communication	The reasons for the premature atherosclerosis in SLE are incompletely understood, although chronic inflammation is thought to play an important role.	23577189
Inflammation, Lupus Erythematosus, Atherosclerosis	Altered Intercellular Communication	This data suggests that the effects of MMF on the immune system may not only be beneficial for lupus, but also for inflammation driving lupus-associated atherosclerosis.	23577189
Inflammation, Calcinosis	Altered Intercellular Communication	An inverse correlation was found between the extension of calcification and cap inflammation (r(2) = 0.017; p = 0.003).	23578355
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Dendritic cells (DCs), the main actors of immune responses and inflammation, may play a role in Alzheimer's disease (AD).	23578995
Inflammatory abnormality of the eye	Altered Intercellular Communication	Mycobacterial ocular inflammation: delay in diagnosis and other factors impacting morbidity.	23579549
Mycobacterium Infections, Inflammatory abnormality of the eye, Tuberculosis	Altered Intercellular Communication	Tuberculosis and atypical mycobacterial infection should be in the differential diagnosis of ocular inflammation, regardless of patient ethnicity.	23579549
Inflammation, Calcinosis, Cerebrovascular accident	Altered Intercellular Communication	Five days after the stroke, a F-fluoride PET/CT to evaluate calcification and, 24 hours later, a F-FDG PET/CT to evaluate inflammation were carried out.	23579977
Tears body substance, Inflammation	Altered Intercellular Communication	Overall the protein modulation shown in POAG tears proves the involvement of biochemical networks linked to inflammation.	23580065
methyldopa, Inflammation, Choroidal Neovascularization	Altered Intercellular Communication	Inflammation and immune cells regulate choroidal neovascularization (CNV) and could become therapeutic targets in age-related macular degeneration (AMD).	23580489
Refractory anemias, Rheumatoid Arthritis, Inflammation, Necrosis	Altered Intercellular Communication	Anti-tumour necrosis factor-alpha (TNF-a) inhibitors provide fast, effective resolution of rheumatoid arthritis (RA) inflammation.	23581251
Inflammation, Intraocular inflammation	Altered Intercellular Communication	He was initially treated with intravitreal bevacizumab and had visual acuity improvement and resolution of the subretinal fluid on OCT. After 8 injections, he developed presumed mild inflammation secondary to intravitreal bevacizumab and was switched to combination intravitreal bevacizumab/dexamethasone in his left eye, which consistently demonstrated efficacy in stabilizing his vision and the CNVM without producing intraocular inflammation.	23581613
Sleep-Disordered Breathing, Inflammation, Chronic Kidney Diseases, Congestive heart failure	Altered Intercellular Communication	ASV improves the prognosis of CHF patients with CKD and SDB, with favorable effects such as the improvement of cardiorenal function and attenuation of inflammation and sympathetic nervous activity.	23582088
Uremia, Inflammation, physiopathological	Altered Intercellular Communication	Protein carbamylation, a posttranslational modification promoted during uremia and catalyzed by myeloperoxidase (MPO) at sites of inflammation, is linked to altered protein structure, vascular dysfunction, and poor prognosis.	23582087
Corneal Endothelial Cell Loss, Inflammatory abnormality of the eye, Cataract, PEX19 gene, Pseudoexfoliation	Altered Intercellular Communication	To compare corneal endothelial cell damage and ocular inflammation after cataract surgery in eyes with and without pseudoexfoliation (PXF).	23582364
Asthma	Altered Intercellular Communication	Switching from salmeterol/fluticasone to formoterol/budesonide combinations improves peripheral airway/alveolar inflammation in asthma.	23583566
Asthma, SFC (Brand Name)	Altered Intercellular Communication	To assess whether switching from SFC to FBC improves peripheral airway/alveolar inflammation in asthma (UMIN000009619).	23583566
Asthma, Complete Blood Count, SFC (Brand Name)	Altered Intercellular Communication	Switching therapy from SFC to FBC improves asthma control and peripheral airway/alveolar inflammation even though there is no improvement in pulmonary functions, and FeNO in asthmatic patients.	23583566
Wounds and Injuries	Altered Intercellular Communication	Recent experimental studies have suggested that chemokines, a subclass of chemoattractant cytokines which play an important role in regulating leukocyte migration and intercellular communication, participate in brain responses of traumatic injury.	23584220
Pain Distress Question, Cysticercosis, Inflammation, Blepharoptosis	Altered Intercellular Communication	Here, we present a case of ocular cysticercosis which presented with mild pain, ptosis, inflammation of upper eyelid and slightly restricted ocular motility.	23584662
Pain Distress Question, Inflammation, Blepharoptosis	Altered Intercellular Communication	A twelve-year-old girl presented with mild pain, unilateral ptosis and inflammation of the right upper eyelid for seven months.	23584662
Intraocular inflammation, Granule, Cytomegalovirus Retinitis, Necrosis of retina, Immune System Diseases	Altered Intercellular Communication	In patients with limited immune dysfunction, a mixed clinical picture of intraocular inflammation with panretinal occlusive vasculopathy, more characteristic of acute retinal necrosis, and peripheral slowly progressive granular retinitis, more characteristic of classic CMV retinitis, is observed.	23584702
Inflammation, Endocrine Glands	Altered Intercellular Communication	Pericardial adipose tissue (PAT), a visceral fat depot surrounding the heart, serves as an endocrine active organ and is associated with inflammation.	23584714
Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	There is growing evidence that atrial fibrillation (AF) is linked with inflammation, which in turn can be a promoter of left atrial remodeling.	23584714
Inflammation, Malnutrition, Cardiovascular Diseases	Altered Intercellular Communication	Malnutrition and inflammation are the most important causes of cardiovascular disease in hemodialysis patients.	23585319
Left ventricular systolic dysfunction, Myocarditis	Altered Intercellular Communication	On multivariate analyses there was no significant relationship between SBP and (1) wall-motion score index (as an index of left-ventricular systolic dysfunction) or (2) T2 enhancement on cardiac magnetic resonance imaging and peak N-terminal pro-brain natriuretic peptide (as indices of myocardial inflammation).	23585361
Hypotension, CTCAE, Orchitis, Systolic dysfunction	Altered Intercellular Communication	Importantly, initial hypotension does not imply severe left ventricular inflammation or systolic dysfunction.	23585361
Data types - Address	Altered Intercellular Communication	In individuals with AD, very limited evidence currently exists to support the hypothesis that AChEIs may influence inflammatory blood markers and function beyond the enhancement of neuronal transmission.	23585364
Inflammation	Altered Intercellular Communication	Such scores were also able to track changes in DAS28-CRP and were significantly associated with both joint inflammation measured by ultrasound and damage progression measured by radiography.	23585841
Atrial Fibrillation, Inflammation, Comorbidity, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Atrial fibrillation (AF) is associated with inflammation and a prothrombotic state; however, it is still unclear whether this is independent of ageing and comorbidity.	23586783
Inflammation, Acanthosis, Keratosis	Altered Intercellular Communication	The 23 biopsy samples of ARK were selected and pathological features were revised (keratosis, acanthosis, surface architecture, and inflammation).	23587097
Inflammation, Ototoxicity, Brain Injuries	Altered Intercellular Communication	HI brain damage was also associated with increases in excitotoxicity (increased glutamate/N-acetylaspartate ratio), oxidative stress (decreased glutathione/creatine ratio and increased protein carbonylation) and inflammation (increased brain IL-1 levels).	23587650
Inflammation, Cutaneous Small Vessel Vasculitis	Altered Intercellular Communication	A renal biopsy showed small-vessel vasculitis with normal glomeruli and inflammation in the interstitium.	23588339
Inflammation, Fibromyalgia, Federated States of Micronesia, Autonomic nervous system disorders, Endothelial dysfunction	Altered Intercellular Communication	Recent evidence suggests that patients with fibromyalgia (FM) have increased oxidative stress, inflammation, endothelial dysfunction and autonomic dysfunction.	23588409
Unconscious State, Wounds and Injuries, Traumatic injury, pituitary dysfunction	Altered Intercellular Communication	Hormonal imbalances may also be observed after mild but repeated trauma without loss of consciousness and should be considered in cases of isolated pituitary dysfunction, since such traumas may often occur in contacts sports such as boxing or intensive soccer play.	23589045
Inflammation, Neoplasm Metastasis, Structure of posterior cerebral artery	Altered Intercellular Communication	In conclusion, MF stromal cells from PCa participate in the progression and metastasis of PCa, modualting inflammation, angiogenesis and epithelial cancer cell proliferation.	23589051
Dehydration, Diarrhea, Inflammatory disease of mucous membrane, Colitis	Altered Intercellular Communication	In Arm2 (n = 33), LBY135 (1-40 mg/kg) plus capecitabine resulted in 3 DLTs (each grade 3): dehydration and mucosal inflammation (1 mg/kg), colitis (20 mg/kg), and diarrhea (40 mg/kg).	23589214
Osteomyelitis, Coxitis, Malignant Neoplasms	Altered Intercellular Communication	Arthrocentesis and needle biopsy of the femoral neck were not diagnostic for malignancy and revealed only mild hip joint inflammation, leading to a diagnosis of osteomyelitis.	23589809
Eosinophilic inflammation	Altered Intercellular Communication	Cluster 1 (n = 69) consisted of patients with severe eosinophilic inflammation-predominant asthma and persistent airflow limitation despite high-intensity anti-inflammatory treatment, with relatively low symptom scores.	23590217
Inflammation, Infection	Altered Intercellular Communication	Body temperature, inflammation, and infections may modify response to thrombolytic therapy.	23590464
Inflammation, Congestive heart failure	Altered Intercellular Communication	The robust association between NT-pro BNP, a diagnostic and prognostic marker in CHF, and sRAGE concentrations might suggest a possible BNP pathway of amplification of inflammation via the AGE/RAGE system.	23590548
Poor fine motor coordination, Parkinson Disease, palladium, Involuntary Movements, Bradykinesia	Altered Intercellular Communication	Parkinson's disease (PD) results from the depletion of dopamine and other neurotransmitters within the basal ganglia, and is typically characterized by motor impairment (e.g., bradykinesia) and difficulty initiating voluntary movements.	23591046
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Chronic inflammation may mediate risk of colorectal cancer (CRC); however, the association between circulating inflammatory markers and risk of CRC has been inconsistent.	23591192
Inflammation, Myocardial Ischemia, Atherosclerosis	Altered Intercellular Communication	Chronic low-grade inflammation is involved in the initiation and progression of atherosclerosis and ischemic heart disease.	23591413
Inflammation	Altered Intercellular Communication	A diet based on marine mammals from the Arctic does not reduce inflammatory activity and it may be speculated that markers of inflammation reflect the disease rather than the cause of the disease.	23591413
Inflammation, Stomach Carcinoma, Gastritis	Altered Intercellular Communication	Moreover, AID expression is highest in the antrum and correlated with severity of chronic inflammation and IM, suggesting an important role for AID in gastric cancer development through gastritis.	23591766
Inflammation, Gastric Intestinal-Type Adenocarcinoma	Altered Intercellular Communication	Local inflammation is a strong risk factor for the development of gastrointestinal adenocarcinomas.	23591979
Inflammation, Myocardial Infarction	Altered Intercellular Communication	The elevation of markers of inflammation and of myocardial necrosis after percutaneous coronary intervention may interfere with clinical outcome.	23592528
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	-374 T/A RAGE polymorphism could be associated with CKD progression and inflammation.	23593165
Inflammation	Altered Intercellular Communication	However, the HGF biologic activity at local inflammation sites was reduced, and this effect was associated with the amount of periodontal bacteria.	23594192
Atherogenesis, Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation has an important place in the formation of atherogenesis and atherosclerosis.	23594688
Inflammation, Arthritis, Membranoproliferative Glomerulonephritis, Type II	Altered Intercellular Communication	This established the diagnosis of CPP crystal deposition disease, while the inflammation of the pubic symphysis was considered as acute crystal deposition arthritis related to calcium pyrophosphate dihydrate crystal deposition.	23595192
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is associated with differential expression of genes involved in inflammation and tissue remodeling.	23595390
Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Micro-inflammation characterized by disturbed Treg/Teff balance with increasing sIL-2R in patients with type 2 diabetes.	23595796
Inflammation	Altered Intercellular Communication	To explore the significance of peripheral CD4(+) regulatory T cells and CD4(+) effector T cells in T2DM, we analyzed inflammation, humoral and cellular immune state in patients with T2DM.	23595796
immunoglobulin A	Altered Intercellular Communication	(1) micro-inflammation state in T2DM: Serum CRP, C3, IgA and plasma sIL-2 R were all significantly higher in T2DM than those in healthy control (HC) (all P<0.05).	23595796
Inflammation	Altered Intercellular Communication	Micro-inflammation state in T2DM was characterized by increased sIL-2 R, elevated CD3(+)CD4(+)T cells and the imbalance of Treg cells and Teff cells, which as one of the pathogeneses took part in inflammation reaction in T2DM.	23595796
Waldenstrom Macroglobulinemia, Pancreatic Intraductal Papillary Mucinous Neoplasm, Fibrosis Assessment, Neoplasms	Altered Intercellular Communication	Using the same criteria, we proceeded to a clinical review of 12 extra cases of IPMN in which the tumour or the surrounding pancreas showed significant lymphoplasmacytic inflammation and/or fibrosis.	23596150
Proteinuria, Inflammation, Glomerulonephritis	Altered Intercellular Communication	[The research on xiaochalhu decoction improving the inflammation of chronic glomerulonephritis patients and relieving the proteinuria].	23596780
Proteinuria, Inflammation, Cancer Genetics Network, Immune System Diseases	Altered Intercellular Communication	XD could improve the inflammation by regulating the immune disorder of CGN patients with Shaoyang disease, which proved that the theory of mediating Shaoyang meridian could be used to improve the inflammation of CGN patients, thus relieving the proteinuria.	23596780
Inflammation	Altered Intercellular Communication	NF-kB is a major regulator of inflammation that controls the expression of many genes involved in atherogenesis.	23597852
Inflammation, Atherosclerosis	Altered Intercellular Communication	Our study demonstrates that targeting NF-kB nuclear translocation hampers inflammation and atherosclerosis development and identifies cell-permeable NLS peptide as a potential anti-atherosclerotic agent.	23597852
ARCN1 gene, Inflammation	Altered Intercellular Communication	Assessments of lung function, allergen testing and sputum analysis for inflammation, bacteria and fungus were undertaken in COPD subjects and healthy smoking and nonsmoking controls.	23598955
Inflammation, Sleep Apnea Syndromes	Altered Intercellular Communication	Sleep apnoea, sleepiness, inflammation and insulin resistance in middle-aged males and females.	23598957
Inflammation, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	In obese males obstructive sleep apnoea (OSA) is associated with inflammation and insulin resistance; however, findings are confounded by adipose tissue, a hormone- and cytokine-secreting organ.	23598957
Inflammation, Osage language	Altered Intercellular Communication	In conclusion, OSA is associated with sleepiness, inflammation and insulin resistance, even in nonobese males, and this association is stronger in males than in females.	23598957
Inflammation, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	In obese males obstructive sleep apnoea (OSA) is associated with inflammation and insulin resistance; however, findings are confounded by adipose tissue, a hormone- and cytokine-secreting organ.	23598957
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Increased hematopoietic cell turnover, chronic inflammation, and reduced immune function have led to speculation that cancer risk may be higher in this group.	23599029
Damage, Acute inflammation	Altered Intercellular Communication	Iris damage, postoperative inflammation, and use of long-term corticosteroids were significantly greater in group I (p<0.001, p<0.001, p=0.005 respectively).	23599193
Inflammation, Traumatic injury, Musculoskeletal Pain, osteitis pubis, Spondylarthropathies	Altered Intercellular Communication	Osteitis pubis is a non-infective inflammation of the symphysis pubis, which is known to be associated with trauma, athletic exertion, urological or gynecological surgery, or with rheumatic conditions such as seronegative spondyloarthropathies.	23599946
Airway structure, Asthma	Altered Intercellular Communication	Respiratory mechanics and peripheral airway inflammation and dysfunction in asthma.	23600542
Airway structure	Altered Intercellular Communication	The correlation between respiratory impedance and spirometry has been reported; however, the association with airway inflammation and pulmonary function, in the lung periphery in particular, is unclear.	23600542
Asthma, physiopathological	Altered Intercellular Communication	To assess whether respiratory impedance is associated with peripheral airway inflammation and dysfunction in asthma.	23600542
Airway structure, Asthma	Altered Intercellular Communication	We sought to determine if the ALOX5 promoter SP1 tandem repeat polymorphism was associated with changes in cysteinyl leukotriene production, lung function, airway inflammation and asthma control score.	23600541
Inflammation, Primary malignant neoplasm, fibrogenesis	Altered Intercellular Communication	Compared with quiescent HSCs, peritumoral HSCs and intratumoral CAMFs expressed considerable up- and down-regulated genes associated with biological process, cellular component, molecular function and signaling pathways involved in fibrogenesis, inflammation and progress of cancer.	23601182
Inflammatory abnormality of the eye	Altered Intercellular Communication	The success rate in reducing corticosteroid to prednisone <= 10 mg/d within 6 months, while maintaining control of ocular inflammation, was 89.7% (95% confidence interval [CI], 81.1-93.5%).	23601800
Inflammation, Neoplasms	Altered Intercellular Communication	Clinical manifestations of XP include mild to extreme sensitivity to ultraviolet radiation resulting in inflammation and neoplasia in sun-exposed areas of the skin, mucous membranes, and ocular surfaces.	23601806
Inflammation, Neoplasms, Eye Abnormalities, Ocular surface disease, Abnormal cornea morphology	Altered Intercellular Communication	Structural eyelid abnormalities, neoplasms of the ocular surface and eyelids, tear film and tear production abnormalities, ocular surface disease and inflammation, and corneal abnormalities were present in this population.	23601806
methyldopa, Inflammation	Altered Intercellular Communication	Recently, complement activation and chronic inflammation have been implicated in the pathogenesis of AMD.	23601964
methyldopa, Inflammation, Disease	Altered Intercellular Communication	While AGEs have been shown to promote inflammation in other diseases, whether it plays a similar role in AMD is not known.	23601964
Inflammation	Altered Intercellular Communication	The main categories were inflammation (interferon-induced, immune response) and proteasome degradation, followed by caspase signaling.	23601964
methyldopa, Inflammation	Altered Intercellular Communication	The pathways and novel genes identified here highlight inflammation as a key response to AGE stimulation in primary culture of human RPE, and identify chemokine CXCL11 as putative novel agent associated with the pathogenesis of AMD.	23601964
Vascular anomaly, Inflammation, Fibrosis Assessment, Deformity	Altered Intercellular Communication	Intralesional injection of pingyangmycin for the treatment of orbital vascular malformations is an effective method that involves mild inflammation, fibrosis, and reduced vascularity of the malformation.	23603483
Communicable Diseases, Inflammation, Lymphoma, Malignant Neoplasms	Altered Intercellular Communication	Other differential diagnosis usually includes malignancy such as lymphoma or metastatic disease, infection, or sterile inflammation.	23603590
Neoplastic, Inflammation, Head and neck structure	Altered Intercellular Communication	To make clinicopathological correlation of head and neck lesions and to assess the frequency of incidences of different sites, age groups, sex, and distribution among inflammation and neoplastic lesion.	23603620
allergic inflammation	Altered Intercellular Communication	Although the high-affinity LTB4 receptor BLT1 has been shown to exert proinflammatory roles, the role of BLT2 in allergic inflammation has not been clarified.	23603839
Asthma	Altered Intercellular Communication	These findings indicate that BLT2 has a protective role in allergic airway inflammation and that diminished BLT2 expression in CD4(+) T cells may contribute to the pathophysiology of asthma.	23603839
Inflammation, Atherosclerosis	Altered Intercellular Communication	Low-grade inflammation plays an independent and important role in atherosclerosis.	23604041
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Association between chronic periodontal and apical inflammation and acute myocardial infarction.	23604464
Inflammation, Fibrosis Assessment, Blood-Retinal Barrier	Altered Intercellular Communication	Loss of blood-retinal barrier (BRB) integrity associated with vitreoretinal fibrin deposition, inflammation, fibrosis and neovascularization contribute to the pathophysiological processes in these disorders.	23604512
Vitreoretinal Area	Altered Intercellular Communication	Retinal pigment epithelial (RPE) cells are well recognized to contribute to vitreoretinal inflammation/fibrosis and are likely to encounter contact with coagulation factor upon loss of BRB integrity.	23604512
PDR gene, Retinitis, Fibrosis Assessment, methyldopa, Disorder of vitreous body	Altered Intercellular Communication	Our findings suggest that factor Xa and thrombin can drive vitreoretinal inflammation and fibrosis and should be considered as treatment targets in vitreoretinal disorders such as PVR, PDR and AMD.	23604512
Encrusted cystitis, Cystitis, Bacterial Infections	Altered Intercellular Communication	Encrusted cystitis is characterized by chronic inflammation of the bladder with encrustation of the mucosa, induced by urea-splitting bacterial infection.	23605319
Inflammation, Gastrointestinal mucositis	Altered Intercellular Communication	Radiotherapy in the head and neck region and chemotherapy might give rise to oral mucositis which is a severe and painful inflammation.	23605599
allergic inflammation	Altered Intercellular Communication	How long-lived Eos, despite the continued presence of GM-CSF or IL-5, eventually undergo apoptosis to end allergic inflammation remains unclear.	23606538
ARCN1 gene, Inflammation	Altered Intercellular Communication	Influence of age, past smoking, and disease severity on TLR2, neutrophilic inflammation, and MMP-9 levels in COPD.	23606791
ARCN1 gene, Inflammation	Altered Intercellular Communication	Efforts to understand the mechanisms of TLR2 signalling and subsequent MMP-9 production in COPD may assist in understanding neutrophilic inflammation in COPD.	23606791
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	There is increasing evidence that inflammation in the synovium plays a major role in the progression of osteoarthritis (OA).	23607395
Inflammation, Thrombosis	Altered Intercellular Communication	Mannan-binding lectin-associated serine proteases (MASPs) MASP-1 and MASP-2 of the complement lectin pathway contribute to clot formation and may represent an important link between inflammation and thrombosis.	23607747
Fibrosis Assessment, prostatitis	Altered Intercellular Communication	Periurethral fibrosis secondary to prostatic inflammation causing lower urinary tract symptoms: a prospective cohort study.	23608423
Fibrosis Assessment, Lower Urinary Tract Symptoms, prostatitis	Altered Intercellular Communication	To investigate the role periurethral fibrosis secondary to chronic prostatic inflammation as a potential contributing factor to the etiology of lower urinary tract symptoms (LUTS) in male patients.	23608423
Inflammation, Leucocytic infiltrate	Altered Intercellular Communication	Of the 30 patients, 21 (70%) presented with inflammatory infiltration and 9 (30%) had no inflammation.	23608423
Inflammation	Altered Intercellular Communication	The histologic evaluation showed a higher collagen quantity (P = .04) and lower, albeit not statistically significant, elastin amount (P = .19) in the inflammation group.	23608423
Lower Urinary Tract Symptoms, prostatitis	Altered Intercellular Communication	Prostate inflammation may induce fibrotic changes in periurethral prostatic tissues, and this may eventually promote urethral stiffness and LUTS.	23608423
palladium, Inflammation, deficiency aspects	Altered Intercellular Communication	It has recently been proposed that inflammation, suggesting as a causal factor for PD, is enhanced by Parkin deficiency.	23608757
Cessation of life, Inflammation	Altered Intercellular Communication	Here, we provide the evidence that Parkin suppresses inflammation and cytokine-induced cell death by promoting the proteasomal degradation of TRAF2/6 (TNF-a receptor-associated factor 2/6).	23608757
palladium, Inflammation	Altered Intercellular Communication	Our results strongly suggest that the reduction of Parkin or overexpression of TRAF2/6 by chronic inflammation would be the reason for occurrence of PD.	23608757
Polymyositis, Myositis, CTCAE 5.0, Abnormal degeneration, Myositis	Altered Intercellular Communication	Sporadic inclusion body myositis (sIBM) and polymyositis (PM) are characterized by muscle inflammation, with sIBM showing additional degenerative alterations.	23608825
Inflammation, Inflammatory disorder	Altered Intercellular Communication	S100A12 is overexpressed during inflammation and is a marker of inflammatory disease.	23611140
Inflammation	Altered Intercellular Communication	Furthermore, it has been ascribed to the group of damage-associated molecular pattern molecules that promote inflammation.	23611140
Sepsis, Inflammation	Altered Intercellular Communication	Human S100A12 is an endogenous TLR4 ligand that induces monocyte activation, thereby acting as an amplifier of innate immunity during early inflammation and the development of sepsis.	23611140
Inflammation	Altered Intercellular Communication	The frequency of iceA2 and its subtype iceA2_D were higher (p<0.015) in cases with moderate/severe granulocytic inflammation.	23611633
Gingivitis, Systemic Scleroderma	Altered Intercellular Communication	Factors associated with gingival inflammation among adults with systemic sclerosis.	23611650
Inflammation, Sample Size Calculation, Scleroderma , Systemic Scleroderma	Altered Intercellular Communication	To identify factors associated with increased gingival inflammation in adults with systemic sclerosis (SSc, scleroderma).	23611650
Degenerative polyarthritis, Inflammation, Pain Distress Question	Altered Intercellular Communication	Cyclooxygenase-2 (COX-2) is a major prostaglandin E2 (PGE2) synthetic enzyme and is involved in the pathogenesis of chronic inflammation and pain in osteoarthritis (OA).	23611898
Inflammation, Anxiety Disorders	Altered Intercellular Communication	Anxiety disorders and inflammation in a large adult cohort.	23612048
Inflammation, Metabolic Syndrome X, Anxiety, CTCAE 3.0, Depression, CTCAE, Anxiety Disorders	Altered Intercellular Communication	Although anxiety disorders, like depression, are increasingly being associated with metabolic and cardiovascular burden, in contrast with depression, the role of inflammation in anxiety has sparsely been examined.	23612048
Inflammation, Anxiety Disorders	Altered Intercellular Communication	In conclusion, elevated inflammation is present in men with current anxiety disorders.	23612048
Inflammation, Necrosis	Altered Intercellular Communication	Thus, the laparotomic wound inflammation and necrosis was 24% less, eventration frequency was 4 times less and the acute respiratory failure was 43% less.	23612338
Inflammation, Osteoporosis	Altered Intercellular Communication	The impact of systemic inflammation, vitamin D insufficiency, air pollution, urban violence and poverty may have long-term bone detrimental outcomes in exposed paediatric populations as they grow older, increasing the risk of low bone mass and osteoporosis.	23612523
Inflammation, Non-Malignant	Altered Intercellular Communication	Semen quality and associated reproductive indicators in middle-aged males: the role of non-malignant prostate conditions and genital tract inflammation.	23612791
Inflammation, Non-Malignant	Altered Intercellular Communication	To compare the associations between non-malignant prostate conditions, genital tract inflammation, and reproductive function in middle-aged men.	23612791
Inflammation	Altered Intercellular Communication	Semen quality and associated reproductive indicators, seminal inflammation, and prostate-related pathologies were evaluated.	23612791
Communicable Diseases, Inflammation, Prostate	Altered Intercellular Communication	According to our data, one of the possible pathways for impaired reproductive quality in male subjects >45 years could be related to infection and inflammation in the genital tract with subsequent (partial) obstruction and damage of prostate and other male accessory glands.	23612791
Proteinuria, Nephritis, Lupus Erythematosus, Systemic	Altered Intercellular Communication	The inverse correlations observed between anti-IFI16 positivity, proteinuria and C3 hypocomplementaemia suggest that anti-IFI16 antibodies do not contribute to renal inflammation in SLE; indeed they may even prevent complement consumption.	23612796
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The outcomes of colorectal cancer are determined by host factors, including systemic inflammation.	23612884
Malignant tumor of colon	Altered Intercellular Communication	The purpose of this study was to evaluate the prognostic significance of fibrinogen and inflammation-based scores, as markers of the inflammatory response, in colon cancer.	23612884
Cataract, Inflammation	Altered Intercellular Communication	Aqueous flare as a marker for inflammation and breakdown of the blood-retinal barrier is increased in patients with CME after cataract surgery.	23613514
Esophagitis	Altered Intercellular Communication	The cure rate of esophageal inflammation was 88.4% in the Nissen group and 67.7% in the Toupet group.	23614820
Inflammatory disease of mucous membrane, Toxic effect, Anorexia	Altered Intercellular Communication	No dose-limiting toxicities were reported; the most common drug-related adverse events were mucosal inflammation and anorexia.	23615181
Intraocular inflammation	Altered Intercellular Communication	Methotrexate proved effective in controlling intraocular inflammation and improving vision in 30 of 38 eyes (79%).	23615343
Inflammation, Benign prostatic hypertrophy, Structure of posterior cerebral artery	Altered Intercellular Communication	Because inflammation may be a common etiological risk factor between PCa and benign prostatic hyperplasia (BPH), the current study was conducted to investigate the association of rs103294 with BPH risk.	23615473
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Our results support a common role of inflammation in the development of PCa and BPH.	23615473
MTA2 gene, Inflammation, borderline ovarian tumor	Altered Intercellular Communication	Our results suggest that a history of PID is associated with an increased risk of ovarian borderline tumors, which may support the hypothesis that inflammation is an etiological factor.	23615817
Inflammation, Aortic Stiffness	Altered Intercellular Communication	Effect of cardiorespiratory fitness on acute inflammation induced increases in arterial stiffness in older adults.	23615823
Inflammation	Altered Intercellular Communication	We tested the hypothesis that acute inflammation may cause arterial stiffening in older adults.	23615823
Inflammation	Altered Intercellular Communication	The high cardiorespiratory fitness group had an attenuated increase in PWV as compared to the low cardiorespiratory fitness group after acute inflammation (p < 0.05).	23615823
Inflammation, Aortic Stiffness	Altered Intercellular Communication	These findings show that acute inflammation may cause significant increases in arterial stiffness in older adults, but these increases were attenuated in the high cardiorespiratory fitness group as compared to the low cardiorespiratory fitness group.	23615823
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	We sought to analyse monocyte polarisation status in type 2 diabetes, which is characterised by chronic inflammation.	23616239
Inflammation, Amyloidosis, Malignant Neoplasms	Altered Intercellular Communication	Retroperitoneal amyloidosis has been described in a few case reports and is typically a secondary manifestation of inflammation or malignancy.	23616327
Inflammation, Observation Method - Coagulation, Adherence (attribute)	Altered Intercellular Communication	Hemodynamics, augmentation index (AIX), leukocyte cell surface adhesion markers, and plasma cytokines involved in vascular adherence, coagulation, and inflammation were measured before and after consumption of the milkshakes.	23616512
ARCN1 gene, Inflammation	Altered Intercellular Communication	To characterize the phenotypes of COPD according to high-resolution computed tomography (HRCT) findings; and to correlate HRCT scores obtained using the modified Bhalla scoring system with clinical and physiological indicators of systemic inflammation.	23616965
Inflammation, Exacerbation	Altered Intercellular Communication	Patients with HRCT findings had lower spirometric measurements and higher levels of inflammation, and reported more exacerbations in the previous year compared with patients with no findings on HRCT.	23616965
Inflammation, Malnutrition, MRSA colonization, Malignant Neoplasms, Comorbidity	Altered Intercellular Communication	History of malignancy and an increased Charlson Comorbidity Index were significant predictors for nasal MRSA carriers, whereas traditional risk factors for MRSA colonization or markers of inflammation or malnutrition were not able to discriminate.	23617360
Manufactured sign, Oculovestibuloauditory syndrome, Orbital Pseudotumor	Altered Intercellular Communication	Typically the ocular signs involve the anterior segment; however there are no descriptions of orbital inflammation associated with Cogan's syndrome.	23617562
Inflammation, Diplopia, Intermittent, Traumatic injury	Altered Intercellular Communication	We report the case of a 52-year-old man who presented with a 10-day history of right eye and eyelid inflammation and intermittent diplopia following blunt trauma to the right eyebrow.	23617582
Narrow Band Imaging, Inflammation, Dysplasia, Thrombopoietin Receptor Agonist LGD-4665, HGD gene	Altered Intercellular Communication	All areas on NBI-DF were classified into three easily distinguishable mucosal patterns: (i) regular pits with regular microvasculature (no dysplasia); (ii) irregular pits with irregular microvasculature (early cancer/high-grade dysplasia [HGD]); and (iii) equivocal, where the endoscopist was not sure about the pattern (this could be areas with increased brownish discoloration on NBI overview and dilated vasculature but no change in caliber on NBI-DF [likely inflammation or low-grade dysplasia: LGD]).	23617668
Inflammation, Dysplasia, Primary malignant neoplasm, Thrombopoietin Receptor Agonist LGD-4665, HGD gene	Altered Intercellular Communication	The 38 areas that appeared suspicious on NBI overview were also further assessed with NBI-DF: seven of seven were accurately predicted as harboring no dysplasia; nine areas were predicted as irregular, of which four harbored early cancer, one HGD, three LGD and one inflammation on final histopathology assessment.	23617668
Inflammation, Thrombopoietin Receptor Agonist LGD-4665	Altered Intercellular Communication	Twenty-two areas were deemed to be equivocal (final histology: 18 LGD and four inflammation).	23617668
Intraocular inflammation, Uveitis	Altered Intercellular Communication	Periocular triamcinolone acetonide injections for control of intraocular inflammation associated with uveitis.	23617776
Intraocular inflammation, Uveitis	Altered Intercellular Communication	To describe the effectiveness of periocular corticosteroid injections for the control of intraocular inflammation associated with noninfectious uveitis.	23617776
Intraocular inflammation	Altered Intercellular Communication	Approximately half of the treated eyes had resolution of intraocular inflammation at 3 months after corticosteroid injection.	23617776
Inflammation, Ground Glass Opacity, Adenomatous hyperplasia, Lung Neoplasms, Bronchioloalveolar Adenocarcinoma	Altered Intercellular Communication	Lung tumors showing ground-glass opacities on high-resolution computed tomography indicate the presence of inflammation, atypical adenomatous hyperplasia, or localized bronchioloalveolar carcinoma.	23618098
Inflammation, Acute appendicitis NOS (disorder)	Altered Intercellular Communication	Interleukin 6 and lipopolysaccharide binding protein - markers of inflammation in acute appendicitis.	23618571
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Acute appendicitis illustrates inflammation development at digestive level and provides for a diagnostic and paraclinical exploration which continually upgrades.	23618571
Inflammation, Atherosclerosis, Carotid Intima-Media Thickness, Plaque, Atherosclerotic	Altered Intercellular Communication	Exposure to biomass fuel smoke has been associated with lung-mediated inflammation and oxidative stress, which may increase the risk of atherosclerosis as evaluated by carotid intima-media thickness (CIMT), carotid atherosclerotic plaque prevalence and blood pressure.	23619984
prostatitis	Altered Intercellular Communication	Fat boosts, while androgen receptor activation counteracts, BPH-associated prostate inflammation.	23620238
Inflammation	Altered Intercellular Communication	Chronic inflammation, a determinant pathogenic factor for BPH, is a putative link between the two conditions.	23620238
ETV3 wt Allele, prostatitis	Altered Intercellular Communication	In a multi-center cohort of BPH patients (n = 244) who underwent prostatectomy, we evaluated whether MetS is associated with prostatic inflammation in BPH specimens.	23620238
prostatitis	Altered Intercellular Communication	Among the different factors, oxidized low-density lipoprotein (oxLDL) showed the highest secretion of IL-8 (>10-fold)-a surrogate marker of prostate inflammation--as well as IL-6, and bFGF.	23620238
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	A pathologic study confirmed that the nonenhancing center of the rim enhancement pattern corresponded to caseous or liquefied necrosis, and homogeneously enhanced portions corresponded to granulomatous inflammation.	23620315
Inflammation, Trauma, Nervous System	Altered Intercellular Communication	In chronically HIV+ adults with long-term viral suppression, current CVD risk, past CVD and age are independent factors for neuronal injury and inflammation.	23620788
Chronic inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	This suggests a tripartite model of HIV, CVD and age likely driven by chronic inflammation.	23620788
Inflammation, Psoriasis	Altered Intercellular Communication	It has been found that many of the triggering factors for psoriasis initiate inflammation by activation of NF-kB.	23621342
Inflammation, Psoriasis, Hyperplasia	Altered Intercellular Communication	The study has demonstrated that translocation of NF-kB in the epidermis and basal cells is responsible for two of the key pathological features of psoriasis, epidermal hyperplasia, and inflammation.	23621342
Granulomatous inflammation, Lymphadenitis, Lymphadenopathy	Altered Intercellular Communication	Tuberculous lymphadenitis is the most common form of lymphadenopathy; its main histopathological finding is granulomatous inflammation.	23621948
Airway structure	Altered Intercellular Communication	Oxidative stress, perhaps modulated by adipokines, may increase airway inflammation in obese individuals.	23622004
Inflammation, Asthma, Obesity	Altered Intercellular Communication	To characterize associations between obesity and asthma in a low-income, urban, minority community and evaluate adipokines, biomarkers of inflammation, and oxidant-antioxidant balance in association with asthma and obesity.	23622004
Inflammation	Altered Intercellular Communication	Our results suggest that IL-21, IL-23, and TGF-b1 may play an important role in the development of site-specific Th17 cell-mediated inflammation in BSRC, which underscore the importance of systemic therapy and offer new insights into the potential of targeted treatments.	23622563
Crohn Disease, Inflammation	Altered Intercellular Communication	To determine the accuracy of high-resolution magnetic resonance enterography (HR-MRE) against surgical and histopathology standards in Crohn's disease, and to determine quantitative MRE findings that can differentiate minor from advanced bowel inflammation.	23622798
Inflammation	Altered Intercellular Communication	Grading of inflammation was compared with MRE parameters for correlation and discriminating power.	23622798
Inflammation, Ulcer	Altered Intercellular Communication	Regression analysis showed deep and superficial ulcers, ER > 1.85 and mural thickness >4.5 mm were independent predictors of advanced inflammation.	23622798
Inflammation, Ulcer	Altered Intercellular Communication	Bowel ulcers, mural enhancement ratio >1.85 are strong predictors of advanced inflammation.	23622798
Inflammation, Neuromyelitis Optica	Altered Intercellular Communication	Complement activation after binding of an IgG autoantibody to aquaporin 4 (AQP4) is thought to be a major determinant of CNS inflammation and astrocytic injury in neuromyelitis optica.	23623397
Inflammation, Neoplasms	Altered Intercellular Communication	Because MRI evaluation showed that the vertebral disc was maintained in this case, the presence of a tumor rather than inflammation should have been suspected.	23623631
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Tacrolimus is effective for the maintenance of refractory UC and can deliver sustained improvement in mucosal inflammation.	23623737
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	It has been reported that inflammation is associated with long-term maintenance of sinus rhythm after electrical cardioversion for non-valvular atrial fibrillation (AF).	23623817
Dimensions, Inflammation	Altered Intercellular Communication	Inflammation, in addition to left atrial dimension, may be associated with successful cardioversion using bepridil.	23623817
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Inflammation has a contributive role in the development and progression of chronic obstructive pulmonary disease (COPD).The present study was designed to determine the level and the distribution of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in COPD compared with controls.	23624662
Inflammation, Pulmonary Complication	Altered Intercellular Communication	Since inflammation has an important contribution in development of future pulmonary and extrapulmonary complications, serum CRP assessment will provide additional information beyond that achieved by conventional method of pulmonary function test.	23624662
Inflammation	Altered Intercellular Communication	BiA pacing is associated with reduction of ANP and markers of inflammation (hs-CRP, IL-6, and neopterin).	23625090
Inflammation, Vasogenic Edema, NRG1 protein, human, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Cerebral amyloid angiopathy-related inflammation (CAA-ri) is characterized by vasogenic edema and multiple cortical/subcortical microbleeds, sharing several aspects with the recently defined amyloid-related imaging abnormalities (ARIA) reported in Alzheimer's disease (AD) passive immunization therapies.	23625526
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Obesity-related immune mediated systemic inflammation was associated with the development of the metabolic syndrome by induction of the tryptophan (TRP)-kynurenine (KYN) pathway.	23625535
Inflammation	Altered Intercellular Communication	Biomarkers of rectal crypt proliferation and systemic inflammation are increased in morbidly obese patients compared with controls.	23625552
Inflammation, Fibrosis Assessment, Cardiovascular Diseases	Altered Intercellular Communication	In cardiovascular diseases including pressure overload-induced HF, perivascular inflammation and cardiac fibrosis are, in part, mediated by monocyte chemoattractant protein (MCP)1-driven monocyte migration.	23625718
Inflammation	Altered Intercellular Communication	rhIL-10-treated rat incisions healed with decreased inflammation, better scar histology, and better macroscopic scar appearance.	23627460
Inflammation, Cicatrization	Altered Intercellular Communication	IL-10 is an important cytokine in wound healing and its suppression of inflammation and scarring is demonstrated in mice and rats with a translational effect in humans.	23627460
Sepsis, Inflammation	Altered Intercellular Communication	A cut-off value of 98 ng/mL distinguished sepsis from systemic inflammation with high sensitivity (0.77) and specificity (0.79).	23627612
Inflammation	Altered Intercellular Communication	Computed tomography-guided biopsy of the bone was completed and revealed chronic inflammation with hematopoietic elements.	23628193
Inflammation, Fibrosis Assessment, Calcinosis, Pancreatitis Necrotizing	Altered Intercellular Communication	The presence of chronic inflammation, fibrosis, and calcification would suggest that this process had been present before birth.We report a 27-day-old newborn with acute necrotizing aortitis.	23629409
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Higher levels of physical activity are associated with lower colorectal carcinoma incidence and mortality, perhaps through influencing energy balance, cellular prosta7 systemic inflammation.	23629521
Inflammation, Pain Distress Question	Altered Intercellular Communication	The clycoxygenase (COX) enzyme forms locally active prostaglandins responsible for producing inflammation and pain.	23629578
Orbital Pseudotumor	Altered Intercellular Communication	Serum immunoglobulin G4 (IgG4)-related systemic disease is a newly found entity and should be considered as a further differential diagnosis to the big pool of unspecific orbital inflammation.	23629783
Orbital Pseudotumor	Altered Intercellular Communication	We retrospectively analyzed all patients with the diagnosis IgG4-related orbital inflammation who were examined in our outpatient clinic.	23629783
Orbital Pseudotumor	Altered Intercellular Communication	Extended unspecific orbital inflammation, especially when bilateral and associated with systemic disease should be considered to be IgG4-related.	23629783
Proteinuria, Inflammation, Hematuria, CTCAE, Anemia	Altered Intercellular Communication	On admission, laboratory findings showed signs of inflammation, anemia, proteinuria, and hematuria.	23631304
Uterine Cervicitis, Infection	Altered Intercellular Communication	Cervicitis is a syndrome of cervical inflammation and a common condition in female sex workers (FSW), a subpopulation vulnerable to sexually transmitted infections.	23631602
Kidney Failure, Chronic, Inflammation, Sarcopenia, Bipolar Disorder	Altered Intercellular Communication	We investigated the prevalence of sarcopenia in elderly patients with end-stage renal disease (ESRD) and its relationship with various markers of nutrition, cognitive function, depressive symptoms, inflammation and b2-microglobulin.	23631844
Inflammation, Fibrosis Assessment, SDSL gene	Altered Intercellular Communication	Inflammation and fibrosis indicate targets for further studies in the pathogenesis of CSDH.	23632762
Atherosclerosis	Altered Intercellular Communication	Resistin is a novel adipokine that is suggested to be involved in inflammatory conditions and atherosclerosis.	23633273
Inflammation, Hematoma, Granulation finding, Mesenteric Cyst	Altered Intercellular Communication	Histopathological investigation showed a mesenteric cyst incorporating a hematoma and tissue with signs of chronic inflammation and granulation.	23633278
Inflammation, Hematoma, Appendicitis, CTCAE, Peritonitis	Altered Intercellular Communication	In the presented case presented hematoma formation and chronic inflammation had presumably induced peritonitis and clinical signs of appendicitis.	23633278
vascular inflammations, Sleep Disorders	Altered Intercellular Communication	Vascular inflammation and sleep disordered breathing in a community-based cohort.	23633759
vascular inflammations	Altered Intercellular Communication	The pathophysiologic mechanisms remain unclear, but enhanced vascular inflammation is implicated.	23633759
Bacteremia, Inflammation, Acute Disease	Altered Intercellular Communication	In contrast, patients with a pulmonary infiltrate or bacteraemia had more inflammation (median C-reactive protein: no infiltrate and no bacteraemia 82 mg/L vs. infiltrate without bacteraemia 163 mg/L vs. bacteraemia 316 mg/L) and higher acute disease severity scores.	23634696
Bacteremia, Inflammation, Lower respiratory tract infection, Acute Disease	Altered Intercellular Communication	Still, there is a clinically important outcome gradient from LRTI patients with pneumococcal isolation only to those with detected pulmonary infiltrate or bacteraemia which is partly mediated by higher acute disease severity and inflammation.	23634696
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Toll-like receptors (TLRs) and the transcription factor nuclear factor-kB (NFkB) are important in inflammation and cancer.	23634849
Inflammation, Fluid overload, Chronic Kidney Diseases	Altered Intercellular Communication	Accumulating evidence suggests an association between body volume overload and inflammation in chronic kidney diseases.	23635012
Inflammation, Atherosclerosis	Altered Intercellular Communication	Pioglitazone, an anti-diabetic agent that improves insulin resistance, was also reported to decrease inflammation and protect against atherosclerosis.	23635096
Inflammation	Altered Intercellular Communication	Those at highest risk for conversion are elderly male patients with prior abdominal surgery who present emergently with laboratory evidence of biliary inflammation.	23635600
Eczematous drug eruption, Inflammation, Dermatitis, Eczema	Altered Intercellular Communication	A subgroup analysis on cases whose skin biopsy specimens showed a pattern of inflammation that is conventionally thought to be associated with eczematous drug eruptions (ie, eczematous and interface dermatitis) was also performed.	23636109
Inflammation	Altered Intercellular Communication	SIRT1 and PPARg, host defenses regulating inflammation and metabolic functions, are suppressed under chronic high oxidant stress and inflammation (OS/Infl) conditions.	23636469
Pain Distress Question, Fibromyalgia, Allodynia, Hyperalgesia, Pain Disorder	Altered Intercellular Communication	Fibromyalgia is a chronic widespread pain disorder in which, the neurogenic origin of the pain, featured by allodynia and hyperalgesia, results from an imbalance in the levels of neurotransmitters and consequently of the peripheral pro- and anti-inflammatory mediators.	23636794
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Pathology, Cardiovascular Diseases	Altered Intercellular Communication	Low grade systemic inflammation (LGSI) as well as androgen deficiency has in older men been associated with several pathologies, including cardiovascular disease (CVD).	23637840
Inflammation	Altered Intercellular Communication	These results demonstrated that local application of H(H2O)m may prevent UV-induced skin inflammation and can modulate intrinsic skin aging and photoaging processes.	23637886
Inflammation, Swelling, Synovitis	Altered Intercellular Communication	Concordance between swelling joint by clinical examination, synovitis thickening by B-mode (grade 1 or higher) and inflammation by power Doppler (grade 1 or higher) was assessed by computing the kappa coefficient.	23639595
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Acute and sub-acute effect of ferric carboxymaltose on inflammation and adhesion molecules in patients with predialysis chronic renal failure.	23640119
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Treatment with parenteral iron causes oxidative stress, inflammation and endothelial dysfunction.	23640119
Inflammation	Altered Intercellular Communication	In contrast, FDG uptake in chronic arthritic joint inflammation was diffuse and mild, without significant change over time, while FDG uptake in nonarthritic joints was at near-background level with decreased activity on delayed images.	23640221
Granuloma, Inflammation	Altered Intercellular Communication	Our finding indicates differential FDG uptake and clearance in active granulomas versus chronic inflammation.	23640221
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Evidence suggests that chronic low-grade inflammation and oxidative stress are related to cardiovascular disease (CVD) and mortality.	23640499
Inflammation, Tumor necrosis	Altered Intercellular Communication	We examined 11 established and novel biomarkers representing inflammation and oxidative stress (C-reactive protein, fibrinogen, interleukin-6, intercellular adhesion molecule-1, lipoprotein-associated phospholipase-A2 [mass and activity], monocyte chemoattractant protein-1, myeloperoxidase, CD40 ligand, P-selectin, and tumor necrosis factor receptor II [TNFRII]) in relation to incident major CVD and mortality in the community.	23640499
APP gene, Inflammation	Altered Intercellular Communication	These findings demonstrated lymphatic vessel involvement in end-stage AAA disease, which was associated with the degree of inflammation, and confirmed the involvement of neovascularization.	23640666
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Weekly EPO dose per kg of dry body weight was positively related to both VEGF-A and angiogenin, whereas no relation was detected among VEGF-A or angiogenin and hemoglobin, inflammation or presence of diabetes mellitus.	23640951
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	These relations among EPO dose and VEGF-A or angiogenin remained after adjustment for hemoglobin concentration or inflammation or presence of diabetes mellitus.	23640951
Inflammation, Demographics Domain, Cardiovascular Diseases, Diabetes Mellitus	Altered Intercellular Communication	Inflammation is a common feature in the majority of cardiovascular disease, including Diabetes Mellitus (DM).	23642086
Communicable Diseases, Inflammatory abnormality of the eye	Altered Intercellular Communication	Patients were tested for all endemic infectious diseases that can cause ocular inflammation by serology or molecular diagnostics.	23642374
Retinitis	Altered Intercellular Communication	The FFA revealed areas of retinal inflammation with indistinct borders, vascular and optic disc leakage, vessel wall staining, or capillary nonperfusion.	23642374
Choroiditis, diabetic	Altered Intercellular Communication	Indocyanine green angiography confirmed choroidal inflammation in 1 of the patients who was diabetic.	23642374
Inflammation, Atrophic retina, Layer of retina	Altered Intercellular Communication	The OCT scan of the macula revealed inner retinal layer edema in active inflammation and retinal atrophy in late stage.	23642374
Inflammation, Cystic Fibrosis	Altered Intercellular Communication	Eighteen patients with fibrotic disease and 19 patients with inflammation were examined.	23643057
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The fibrosis group had lower blood volume (0.9 vs. 3.4 mL per 100 mL tissue; p = 0.001) and flow (22.6 vs. 45.3 mL/min per 100 mL tissue; p = 0.003) compared with the inflammation group.	23643057
Neurogenic Inflammation, Dermatologic disorders, Rosacea	Altered Intercellular Communication	Rosacea is a common skin disease, involving neurogenic inflammation and neurovascular dysregulation.	23643255
Migraine Disorders, Inflammation	Altered Intercellular Communication	Migraine has been associated with vascular changes and sterile inflammation.	23643255
Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation markers predict zinc transporter gene expression in women with type 2 diabetes mellitus.	23643522
Inflammation, Demographics Domain, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The pathology of type 2 diabetes mellitus (DM) often is associated with underlying states of conditioned zinc deficiency and chronic inflammation.	23643522
Inflammation, Cerebral Ischemia	Altered Intercellular Communication	Pro-inflammatory cytokine network in peripheral inflammation response to cerebral ischemia.	23643982
Inflammation, Acute cerebral ischemia	Altered Intercellular Communication	The key circulating pro-inflammatory cytokines and their interaction in peripheral inflammation after acute cerebral ischemia are poorly understood.	23643982
Inflammation, Depression, CTCAE, Cerebral Ischemia	Altered Intercellular Communication	Pro-inflammatory cytokines up-regulation in plasma and compensatory immunity depression in leukocyte involve in peripheral inflammation response to cerebral ischemia.	23643982
Inflammation, Pancreatitis, Malnutrition, Liver Cirrhosis	Altered Intercellular Communication	Cirrhosis and chronic pancreatitis (CP) are accompanied by inflammation and malnutrition.	23644391
Inflammation	Altered Intercellular Communication	Cell cycle regulation, apoptosis, oxidative stress and inflammation response play critical roles in the development of smoking-induced lung cancer.	23644744
Inflammation	Altered Intercellular Communication	The imbalance between inflammation and anti-inflammation may be part of the mechanism.	23645243
Autoimmune Hypophysitis	Altered Intercellular Communication	Autoimmune hypophysitis (AH) is commonly believed to be a rare chronic inflammatory condition of the pituitary gland.	23645305
Inflammation, Respiration Disorders, Hypoxia	Altered Intercellular Communication	Serum uric acid is increased in respiratory disease, especially in the presence of hypoxia and systemic inflammation.	23645404
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is associated with systemic inflammation and oxidative stress.	23645408
Inflammation, Sleep Apnea, Central, Heart failure, Cardiac Arrhythmia	Altered Intercellular Communication	Central sleep apnoea and inflammation are independently associated with arrhythmia in patients with heart failure.	23645499
Malnutrition, HD Term Type, Inflammation	Altered Intercellular Communication	Resistance to erythropoietin (EPO) treatment has been associated with inflammation and malnutrition in hemodialysis (HD) patients.	23645578
Inflammation, Malnutrition, Depression, CTCAE, Bipolar Disorder	Altered Intercellular Communication	Depression has also been associated with both inflammation and malnutrition; however, the specific relationship between depressive symptoms and EPO resistance is not known.	23645578
Inflammation	Altered Intercellular Communication	Telomerase activity was independently associated with LTL (p = 0.007) and negatively modulated by inflammation and oxidative stress.	23646142
Inflammation	Altered Intercellular Communication	According to the last reports, the role of chronic minimal inflammation in colon mucosa is becoming more relevant.	23646443
Inflammation	Altered Intercellular Communication	Mild inflammation of colonic mucosa in lamina propria was observed in 92% patients, 34% presented other inflammatory cells.	23646443
Inflammation, Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	Low grade inflammation of lamina propria in colon was observed among patients with IBS.	23646443
Inflammation, Chronic disease	Altered Intercellular Communication	To test the hypothesis that changes in air pollution levels are associated with changes in biomarker levels reflecting inflammation, hemostasis, oxidative stress, and autonomic tone, we recruited and retained 125 nonsmoking adults (19 to 33 years old) free of cardiorespiratory and other chronic diseases.	23646463
Inflammatory disease of mucous membrane	Altered Intercellular Communication	The perioperative application of BLFNI could alleviate postoperative mucosal inflammation, shorten the cavity cleaning time, speed up the process of epithelization, improve the QOL, and elevate the operative efficacy.	23646471
Inflammation	Altered Intercellular Communication	Nucleic acid sensing has emerged as one of the important components of the immune system triggering inflammation.	23646855
Inflammation	Altered Intercellular Communication	This study highlights a possible role for nucleic acid receptors in periodontal inflammation.	23646855
Inflammation, Asthma	Altered Intercellular Communication	We suggest that the studied cytokines, with a stronger indication for leptin, can elicit asthmatic inflammation in obese phenotype of asthma that affects more frequently women.	23648099
Neurodegenerative Disorders, Inflammation, Abnormality of mitochondrial metabolism, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	These age-related neurodegenerative diseases including Alzheimer's disease (AD) are associated with mitochondrial dysfunction, oxidative stress, and inflammation.	23648515
Fatigue	Altered Intercellular Communication	We assessed serum and fecal markers of intestinal inflammation/injury and immune activation, and indices of fatigue.	23648697
Inflammation, Pancreatitis, Haemoconcentration	Altered Intercellular Communication	Early measures of hemoconcentration and inflammation are predictive of prolonged hospitalization from post- endoscopic retrograde cholangiopancreatography pancreatitis.	23648842
Inflammation	Altered Intercellular Communication	Senescent cells also secrete inflammatory cytokines such as IL-6, which promote age-associated inflammation and pathology.	23649808
Inflammation	Altered Intercellular Communication	Our findings identify senescence as a novel biological setting in which HMGB1 functions and link HMGB1 redistribution to p53 activity and senescence-associated inflammation.	23649808
Chronic lymphocytic inflammation, Pontine structure, B-Cell Lymphomas	Altered Intercellular Communication	Fatal B-cell lymphoma following chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids.	23649857
Chronic lymphocytic inflammation, Pontine structure, Clippers	Altered Intercellular Communication	Recent reports on chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) suggest that patients who have a relapse respond very well and that disease progression can be avoided if timely corticosteroid therapy is started.	23649857
Inflammation	Altered Intercellular Communication	DES showed an increase in inflammatory cytokines in the late phase after implantation in comparison with patients who received BMS, suggesting late-stage inflammation.	23649933
Presenile dementia, Inflammation, Bipolar Disorder	Altered Intercellular Communication	Longitudinal relationship of low leisure satisfaction but not depressive symptoms with systemic low-grade inflammation in dementia caregivers.	23650246
Inflammation, Depression, CTCAE, Bipolar Disorder	Altered Intercellular Communication	We hypothesized that both elevated depressive symptoms and a behavioral correlate of depression, low leisure satisfaction, are associated with systemic inflammation.	23650246
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Depressive symptoms did not mediate the relationship between leisure satisfaction and inflammation.	23650246
Inflammation, Leukemogenesis, Leukemia, Myelocytic, Acute	Altered Intercellular Communication	Although high miR-155 expression was not associated with a distinct microRNA expression profile, it was associated with a gene expression profile enriched for genes involved in cellular mechanisms deregulated in AML (eg, apoptosis, nuclear factor-kB activation, and inflammation), thereby supporting a pivotal and unique role of this microRNA in myeloid leukemogenesis.	23650424
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Despite the fact that low plasma zinc (Zn) levels play important roles in the oxidative stress, the relationships between lipid peroxidation and inflammation biomarkers with low plasma Zn levels have not been investigated in chronic kidney disease (CKD) patients.	23650973
HD Term Type, Inflammation	Altered Intercellular Communication	In conclusion, reduced Zn levels were associated with lipid peroxidation and inflammation, and we confirm here in a Brazilian cohort of HD patients that inflammation markers are strong predictors of CV death.	23650973
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Our study shows that ACS associates with low HDL-C and biomarkers of oxidative stress and inflammation.	23651064
Autoimmune Diseases, Inflammation, TRPV6 gene, Tropical Spastic Paraparesis	Altered Intercellular Communication	Moreover, because abrogation of OX40 signals ameliorates chronic inflammation in animal models of autoimmune disease, novel monoclonal antibodies against OX40 may offer a potential treatment for HTLV-1-associated diseases such as ATL and HAM/TSP.	23651542
Colitis, Inflammation, Diarrhea, Irritable Bowel Syndrome	Altered Intercellular Communication	Low prevalence of 'classical' microscopic colitis but evidence of microscopic inflammation in Asian irritable bowel syndrome patients with diarrhoea.	23651739
Inflammation, Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	There is increasing evidence for the role of microscopic inflammation in patients with IBS.	23651739
Inflammation, Ichthyosis Bullosa of Siemens, Diarrhea, Colitis	Altered Intercellular Communication	We aimed to examine the prevalence of microscopic colitis and inflammation in Malaysian IBS patients with diarrhoea (IBS-D).	23651739
Inflammation	Altered Intercellular Communication	However, the IBS-D patients had a higher prevalence of moderate microscopic inflammation (n = 11, 14.9%) compared to controls (n = 1, 2.2%) (p = 0.005).	23651739
Inflammation, Colitis	Altered Intercellular Communication	'Classical' microscopic colitis is uncommon in Malaysian patients with IBS-D but a significant number of adults showed evidence of microscopic inflammation.	23651739
Inflammation, Obesity	Altered Intercellular Communication	In a group of school-aged Mexican children, obesity increases cardiovascular risk and inflammation.	23652186
Inflammation, Cardiovascular system alteration, Obesity	Altered Intercellular Communication	More research is needed in order to explore the role of subclinical inflammation in the development of cardiovascular alterations that have already been described in Mexican children with obesity.	23652186
vascular inflammations	Altered Intercellular Communication	Peroxisome proliferator-activated receptor g (PPARg) is a ligand-activated transcription factor that regulates the gene expression of the key proteins involved in lipid metabolism, vascular inflammation, and proliferation.	23652363
Inflammation	Altered Intercellular Communication	Social isolation and adult mortality: the role of chronic inflammation and sex differences.	23653312
Inflammation	Altered Intercellular Communication	A high-risk fibrinogen level and cumulative inflammation burden may be particularly important in this link.	23653312
Hemorrhagic, Inflammation	Altered Intercellular Communication	Histopathological analysis revealed seminoma of the right testis and dilated right vesicula seminalis filled with hemorrhagic fluid and sings of chronic inflammation.	23654019
Inflammation, Numerous, Lupus Erythematosus, Systemic, Autoimmune Diseases, Lupus Erythematosus	Altered Intercellular Communication	Systemic lupus erythematosus (SLE) is a polymorphic and multigenic autoimmune disease that evolves into progressive and chronic inflammation of multiple joints and organs.	23656347
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Recent advances demonstrate a relationship between chronic/recurrent inflammation and prostate cancer (PCA).	23657238
Malignant Biliary Obstruction	Altered Intercellular Communication	Usefulness of an inflammation-based prognostic score (mGPS) for predicting survival in patients with unresectable malignant biliary obstruction.	23657751
Primary malignant neoplasm	Altered Intercellular Communication	An inflammation-based prognostic score, the modified Glasgow Prognostic Score (mGPS), has been established as a useful tool for predicting postoperative outcome in patients with cancer.	23657751
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Monocyte chemoattractant protein-1 (MCP-1) and its receptor CC chemokine receptor 2 (CCR2) play a major role in inflammation and proliferation of cancers.	23657965
Inflammation, Diabetic Angiopathies, Chronic Kidney Diseases	Altered Intercellular Communication	PTX3 may be involved in adipose tissue-orchestrated mechanisms that are restricted to the uremic milieu and modify inflammation and vascular complications in CKD patients.	23658833
Inflammation, Anemia, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Anemia developing in CHD patients may cause not only inflammation but also depletion of iron reserves.	23659067
Inflammation, Rheumatic Fever	Altered Intercellular Communication	Increased ischaemia-modified albumin is associated with inflammation in acute rheumatic fever.	23659227
Inflammation, Rheumatic Fever	Altered Intercellular Communication	The increased level of ischaemia-modified albumin in children with acute rheumatic fever seems to be associated with inflammation.	23659227
Axonal degeneration, Inflammation	Altered Intercellular Communication	A better understanding of the influence of the inflammation on sodium channels mediated axonal degeneration could offer therapeutic perspectives.	23659577
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Elevated circulating cytotoxic T lymphocyte-associated antigen-4 levels are related to lung function and inflammation in chronic obstructive pulmonary disease.	23659585
Inflammation	Altered Intercellular Communication	Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is involved in immune and inflammation regulation.	23659585
NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology, Inflammation, Cytopenia, Leukemia, Large Granular Lymphocytic	Altered Intercellular Communication	The final diagnoses included 17 patients with myelodysplastic syndrome, 9 patients with pure red cell aplasia (non-large granular lymphocytosis [LGL] in etiology], 15 patients with LGL (eight of whom had a single-lineage cytopenia only, whereas the other seven had multilineage cytopenias), and 7 patients with cytopenias associated with systemic inflammation from autoimmune conditions.	23660070
Inflammation, Cytopenia, Pancytopenia	Altered Intercellular Communication	Our data suggest that low BFU-E growth (less than 10 BFU-E per 10(5) marrow mononuclear cells) helps to exclude LGL, pure red cell aplasia, or cytopenias associated with systemic inflammation as a cause of pancytopenia with a sensitivity of 96.8%, specificity of 76.5%, and a predictive value of 88.2% (p = 0.0001).	23660070
Pain Distress Question, Acute inflammation	Altered Intercellular Communication	The pain and postoperative inflammation were successfully controlled with an analgesic and an anti-inflammatory drug.	23660343
Inflammation, Malignant neoplasm of sigmoid colon, Crohn Disease	Altered Intercellular Communication	After surgery, histopathology revealed acute/chronic diverticular inflammation only in 29 cases, and superimposed sigmoid cancer (n = 2) or Crohn's disease (n = 1) in 3 patients with a DDSS of 4.	23660775
Inflammation	Altered Intercellular Communication	The relationship between inflammation, degeneration (IVD), and cytokine upregulation is well established, but other mediators of the inflammatory cascade are not well characterized.	23660804
Carcinogenesis, Malignant Neoplasms	Altered Intercellular Communication	Although the role of microRNAs (miRs) in GBC have not been well documented, miR-155 is known to be associated with inflammation-associated carcinogenesis in various types of cancers.	23660842
Inflammation, Exfoliation Syndrome, Endothelial dysfunction	Altered Intercellular Communication	Serum YKL-40 levels as a novel marker of inflammation and endothelial dysfunction in patients with pseudoexfoliation syndrome.	23661157
Inflammation, Tuberculosis	Altered Intercellular Communication	The histology revealed caseating, transmural granulomatous inflammation consistent with tuberculosis.	23661658
Inflammation, Lupus Erythematosus	Altered Intercellular Communication	Invariant natural killer T cells are enriched at the site of cutaneous inflammation in lupus erythematosus.	23664188
Lupus Erythematosus	Altered Intercellular Communication	The deficiency in circulating iNKT cells in cutaneous lupus erythematosus is associated with an increase of iNKT cells at the site of cutaneous inflammation.	23664188
Malignant neoplasm of urinary bladder, Inflammation, Pyuria	Altered Intercellular Communication	To evaluate the significance of inflammation in non-muscle-invasive bladder cancer (NMIBC), we assessed the presence of pyuria at time of diagnosis.	23664207
Inflammation, Pterygium Of Conjunctiva And Cornea	Altered Intercellular Communication	Ocular demodicosis is a risk factor for pterygium recurrence, especially for conjunctival recurrence, presumably by perpetuating chronic inflammation mediated by T-helper (Th)17 lymphocytes.	23664471
Oropharyngeal, Inflammation, Lemierre Syndrome, Thrombosis	Altered Intercellular Communication	Severe oropharyngeal infection can result in Lemierre's disease, a syndrome with high mortality secondary to inflammation and thrombosis of cervical and intracranial veins with involvement of contiguous structures; however arterial involvement is rare.	23664903
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Aggregate risk score based on markers of inflammation, cell stress, and coagulation is an independent predictor of adverse cardiovascular outcomes.	23665099
Inflammation, Steatohepatitis, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Fatty Liver Disease	Altered Intercellular Communication	Disease progression in non-alcoholic fatty liver disease (NAFLD) is not well understood and there is controversy about whether non-alcoholic fatty liver (NAFL, i.e., steatosis alone or with mild inflammation not qualifying for steatohepatitis) can evolve towards steatohepatitis (NASH) with fibrosis.	23665288
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Patients with mild lobular inflammation or any degree of fibrosis were at higher risk of progression than those with steatosis alone.	23665288
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Even mild inflammation or fibrosis could substantially increase the risk of progression when compared to steatosis alone.	23665288
Inflammation, Glycation End Products, Advanced, Atherosclerosis	Altered Intercellular Communication	High sensitivity C-reactive protein (hsCRP) and advanced glycation end-products (AGEs) have been proposed as mediators in inflammation and atherosclerosis.	23665412
Inflammation, Colitis	Altered Intercellular Communication	Oral administration of d-limonene controls inflammation in rat colitis and displays anti-inflammatory properties as diet supplementation in humans.	23665426
vascular inflammations	Altered Intercellular Communication	Lectin-like oxidized low-density lipoprotein receptor-1 plays an important role in vascular inflammation in current smokers.	23665840
vascular inflammations	Altered Intercellular Communication	Smoking induces vascular inflammation and increases the risk of cardiovascular events.	23665840
Inflammation, Atherosclerosis	Altered Intercellular Communication	These findings suggest that LOX-1 may therefore play an important role in the onset of smoking-induced inflammation and atherosclerosis in humans.	23665840
Inflammation, Endothelial dysfunction, atherosclerotic	Altered Intercellular Communication	The ApoB/A1 ratio was associated with the d-ROMs, a marker of oxidative stress, endothelial dysfunction and inflammation, and could be useful as a residual atherosclerotic risk marker to help prevent CAD in statin-treated patients.	23665841
Inflammation, Infection	Altered Intercellular Communication	The mechanism responsible for such harmful association is probably indirect, and involves the weakening of platelet-neutrophil-endothelial crosstalk necessary to combat infections, and/or keep inflammation from spreading.	23665886
Hepatitis	Altered Intercellular Communication	Indeed, NKp46-rich NK populations were the most activated, correlating closely with the severity of liver inflammation.	23665989
Inflammation, Eisenmenger Complex	Altered Intercellular Communication	Inflammation may be an important contributing factor to the progression of Eisenmenger syndrome (ES).	23666048
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Neutrophil to lymphocyte ratio (NLR) is widely used as a marker of inflammation and an indicator of cardiovascular outcomes in patients with coronary artery disease.	23666299
Inflammation, Somnolence, Hemorrhagic, Cessation of life, Kidney Failure	Altered Intercellular Communication	The primary risk factors associated to death were kidney or respiratory failure, somnolence, hemorrhagic manifestations and a syndrome of systemic inflammation.	23666663
Inflammation	Altered Intercellular Communication	Age-related telomere uncapping is associated with cellular senescence and inflammation independent of telomere shortening in human arteries.	23666675
Inflammation, Arteritis	Altered Intercellular Communication	Arterial telomere dysfunction may contribute to chronic arterial inflammation by inducing cellular senescence and subsequent senescence-associated inflammation.	23666675
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Lysophosphatidic acid (LPA) is a bioactive lipid that binds to a group of cell surface G protein-coupled receptors (LPA receptors 1-6 [LPA1-6 ]) and has been implicated as an important mediator of angiogenesis, inflammation, and cancer growth.	23666827
Abscess, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Ultrasound scan revealed a necrotic abscess suspicious of malignancy and biopsy showed evidence of chronic inflammation.	23667218
Inflammation, MS gene, Nerve injury	Altered Intercellular Communication	Intense inflammation and nerve damage in early multiple sclerosis subsides at older age: a reflection by cerebrospinal fluid biomarkers.	23667585
Inflammation, Trauma, Nervous System, Axonal loss, Physical disability, MS gene	Altered Intercellular Communication	The extent of neuronal injury and axonal loss are associated with the degree of CNS inflammation and determine physical disability in multiple sclerosis (MS).	23667585
nervous system disorder, Inflammation	Altered Intercellular Communication	Levels of matrix metalloproteinase 9 (MMP9), chemokine (C-X-C motif) ligand 13 (CXCL13), osteopontin (OPN) and neurofilament-light chain (NFL) were measured by ELISA in 548 subjects comprising different MS subtypes (relapsing-remitting, secondary progressive and primary progressive), clinically isolated syndrome and persons with other neurological diseases with or without signs of inflammation/infection.	23667585
Renal Insufficiency, Inflammation, Calcinosis, Vascular calcification	Altered Intercellular Communication	The case demonstrates that while mechanisms of vascular calcification are poorly understood, inflammation per se might be sufficient to mediate increased mineral stress leading to vessel calcification, even in the absence of renal impairment.	23668269
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The oat-enriched diet had a modest impact on lipid lowering, but did not impact on oxidative stress or inflammation in these volunteers with Type 2 diabetes.	23668675
Gastrointestinal inflammation	Altered Intercellular Communication	LCN2 is a putative biomarker in faeces for intestinal inflammation, different from calprotectin due to its epithelial site of synthesis.	23668802
Pneumonitis	Altered Intercellular Communication	As quantified by blinded scoring of lung pathology, P. acnes-induced granulomatous pulmonary inflammation was markedly attenuated in TLR-2(-/-) mice compared to wild-type C57BL/6 animals.	23668840
Inflammation, Carcinoma, Squamous cell carcinoma, Squamous intraepithelial lesion, Cervical intraepithelial neoplasia grade 2, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	Cell smear findings suggested atypical squamous cells in 148 patients, low-grade squamous intraepithelial lesion in 62 patients, and high-grade squamous intraepithelial lesion in 107 patients, squamous cell carcinoma in 56 patients, and cervical biopsy-revealed inflammation in 89 patients, cervical intraepithelial neoplasia (CIN) I in 36 patients, CIN II in 43 patients, CIN III in 129 patients, and infiltrating carcinoma in 76 patients.	23669440
Inflammation, Communicable Diseases, Ductal Carcinoma, Cervical intraepithelial neoplasia grade 2, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	In the inflammation, CIN I, CIN II, CIN III, and infiltrating carcinoma groups, the infection rates of HR-HPV were 29.21%, 52.78%, 74.42%, 92.25%, and 93.42% (P < 0.01), respectively; the positive rates of hTERC gene amplification were 0.00%, 13.89%, 41.86%, 78.29%, and 89.47% (P < 0.01), respectively.	23669440
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP) is a well-known biomarker of systemic inflammation and cardiovascular disease.	23669654
Inflammation, Lymphohistiocytosis, Hemophagocytic	Altered Intercellular Communication	Familial hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening condition characterized by immune hyperactivation and clinical signs of extreme inflammation.	23669735
Inflammation, Superinfection	Altered Intercellular Communication	The critical feature is a skin barrier dysfunction that leads to epidermal inflammation and to bacterial superinfection.	23670066
Inflammation	Altered Intercellular Communication	Conjunctival inflammatory cell density and MG inflammation were increased in each group compared with those in controls (p < 0.001), with the highest values in SSI.	23670123
Inflammation, Hemorrhage, Gastrointestinal Pain, CTCAE, Pulmonary Embolism, Communicable Diseases, Diarrhea, Infection, Erythema, Peripheral edema, Deep thrombophlebitis	Altered Intercellular Communication	There were no significant differences in asymptomatic DVT, symptomatic DVT, symptomatic pulmonary embolism, or bleeding, but there were increases in other adverse events (including receipt of blood transfusion, erythema, peripheral edema, diarrhea, gastrointestinal or abdominal pain) and infections (including respiratory tract or lung infections, wound inflammation or infection, and extrasurgical-site infections), in patients with a BMI of 40 kg/m2 or greater compared with patients with a BMI less than 40 kg/m2.	23670675
Inflammation, Hemorrhage, Gastrointestinal Pain, CTCAE, Communicable Diseases, Diarrhea, Infection, Erythema, Postoperative Complications, Obesity, Peripheral edema, vinyltriethoxysilane	Altered Intercellular Communication	After THA or TKA, morbid obesity is not associated with an increased risk of VTE or bleeding but is associated with increased early postoperative complications, including erythema, peripheral edema, diarrhea and gastrointestinal or abdominal pain, wound inflammation or infection, extrasurgical-site infections, and respiratory tract or lung infections.	23670675
Inflammation, Cardiac complication, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Understanding the interplay between adiposity, inflammation, and cardiovascular complications in type 2 diabetes mellitus (T2DM) remains a challenge.	23670978
Inflammation, Cardiac complication	Altered Intercellular Communication	However, further understanding the interplay between adiposity, plasma lipids, and inflammation may prove important in the prediction and management of cardiovascular complications in T2DM.	23670978
Presenile dementia, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Many factors contribute to the etiology of depression and dementia, being inflammation one of those.	23671023
Inflammation, Inflammatory disorder, Coronary heart disease	Altered Intercellular Communication	The deletion variant allele of the NFKB1 - 94ins/delATTG promoter polymorphism leads to lower transcript levels of the p50 subunit, and the variant allele has been associated with the risk of several inflammatory diseases as well as coronary heart disease where inflammation is important in the pathogenesis.	23671649
Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	These changes are indicative of inflammation and may be involved in the prodromal processes leading to the development of neurodegenerative disease.	23671673
Inflammation, Urinary Calculi, Urolithiasis	Altered Intercellular Communication	We focused on alpha 1-antitrypsin (alpha1-AT), a protein verified to be present in urinary calculi, and which is considered as a protein of inflammation, comparing its presence in healthy subjects and patients with urolithiasis.	23672078
Communicable Diseases, Pneumonitis	Altered Intercellular Communication	The degrees of pulmonary inflammation and the number of organisms were much enhanced in T-bet-/- mice than in wild-type mice and T-bet tg/tg mice after MAC infection.	23672176
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Methylated arginines and nitric oxide in end-stage renal disease: impact of inflammation, oxidative stress and haemodialysis.	23672496
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	To determine whether inflammation (C-reactive protein, CRP), oxidative stress (malondialdehyde, MDA) or haemodialysis (HD) affect associations between asymmetric (ADMA), symmetric (SDMA) dimethylarginine, NG-monomethyl-L-arginine (L-NMMA) and nitrite/nitrate (NOx) in end-stage renal disease (ESRD).	23672496
Kidney Failure, Chronic, HD Term Type, Inflammation	Altered Intercellular Communication	HD, oxidative stress or inflammation did not significantly affect the positive associations between methylated arginines and NOx in ESRD.	23672496
Refractory anemias, Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Within RA, coagulation factors were assessed alongside several demographic, inflammation and metabolic indicators.	23673438
Refractory anemias, Inflammation	Altered Intercellular Communication	Imbalance of coagulation and fibrinolytic mechanisms is common in RA and associates with age, inflammation, and metabolic factors.	23673438
Inflammation, physiopathological	Altered Intercellular Communication	Further studies may determine whether these abnormalities are the consequence of acute inflammation or markers of vascular dysfunction.	23673438
Inflammation, Gastric Stump	Altered Intercellular Communication	The endoscopic severity of remnant gastritis, as well as histological inflammation and activity, were higher in H. pylori-positive patients than in H. pylori-negative patients.	23673508
Burn injury	Altered Intercellular Communication	Normal abdominal expansion that occurs as a result of hormonal actions during pregnancy may be prevented by the presence of excessive scar tissue in individuals who have received severe burns.	23673563
Rheumatoid Arthritis, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Rheumatoid arthritis and atypical cardiovascular disease: inflammation changing the clinical presentation.	23673587
Inflammation, Pulmonary Embolism, Thrombophilia, Cardiovascular Diseases	Altered Intercellular Communication	Although associated with adverse outcomes in other cardiovascular diseases, the prognostic value of an elevated white blood cell (WBC) count, a marker of inflammation and hypercoagulability, is uncertain in patients with pulmonary embolism (PE).	23674436
Chronic suppurative inflammation	Altered Intercellular Communication	Partial resection of the small intestine was performed, and pathological analysis suggested chronic suppurative inflammation in all layers of the ileal wall and mesentery.	23674862
Inflammation, Left ventricular diastolic dysfunction	Altered Intercellular Communication	Dissecting the mechanisms of left ventricular diastolic dysfunction and inflammation in peritoneal dialysis patients.	23675418
Inflammation	Altered Intercellular Communication	We hypothesized that adiposity might influence LV diastolic function through systemic inflammation in this specific group.	23675418
Diastolic dysfunction	Altered Intercellular Communication	Subjects with LV diastolic dysfunction had higher levels of the pro-inflammation cytokines and more visceral and peritoneal fat (all P<0.001) than control subjects.	23675418
Reduced FEV1/FVC ratio, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Systemic inflammation, depression and obstructive pulmonary function: a population-based study.	23676005
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Depression, CTCAE, Chronic disease	Altered Intercellular Communication	Levels of Interleukin-6 (IL-6) and C-creative protein (CRP) indicating systemic inflammation are known to be elevated in chronic diseases including chronic obstructive pulmonary disease (COPD) and depression.	23676005
Cataract, Inflammation	Altered Intercellular Communication	[Post-operational acute inflammation of an eye in patients with cataracts].	23676483
Inflammation, Endophthalmitis, CTCAE, Poisoning syndrome in animal	Altered Intercellular Communication	On the basis of obtained data is found that clinical symptomatology of autoimmune aseptic anterior uveitis, in particular, the eye inflammation associated with the broken syndrome of an eye anterior chamber-associated immune deviation (ACAID), considerably differs from clinical implications of acute endophthalmitis and a toxic syndrome of the anterior chamber of an eye.	23676483
Inflammation, Periodontal Diseases	Altered Intercellular Communication	Objective of our work: To carry out a comparative assessment of the expression level p53 protein and associate it with the degree of DNA damage in inflammation of periodontal disease.	23676490
Inflammation	Altered Intercellular Communication	It was established that acute inflammation in the periodontal tissues develop changes leading to DNA damage Acute inflammation is characterized by high levels of p53 Considerable damage to the nuclear DNA is called p53.	23676490
Abnormal inflammatory response	Altered Intercellular Communication	Topical steroids for chronic wounds displaying abnormal inflammation.	23676816
Inflammation, Hypertension, CTCAE, Atherosclerosis	Altered Intercellular Communication	Inflammation has a role in the pathogenesis of atherosclerosis, which causes hypertension.	23676848
Inflammation	Altered Intercellular Communication	The pharmacological action of metformin goes beyond mere glycemic control, decreasing markers of inflammation and contributing to the reduction of oxidative stress.	23677182
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	The role of individual monocyte subsets in inflammation and recovery post-myocardial infarction (MI) is insufficiently understood.	23677452
Pain Distress Question, Swelling, Inflammation	Altered Intercellular Communication	Pain, inflammation or swelling of soft tissues orjoints is often treated with oral or topical formulation of lbuprofen.	23678669
Pain Distress Question, Swelling, Traumatic injury, Inflammation	Altered Intercellular Communication	A total of 170 patients suffering either from pain, inflammation or swelling of soft tissues or joints or having experienced a blunt trauma were enrolled into this study.	23678669
Inflammation, HIV Infections	Altered Intercellular Communication	The possible influence of CRT on the inflammation state related to chronic HIV infection was also examined.	23678991
Autoimmune Diseases, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	IL-10, a pleiotropic cytokine produced by macrophages, T-helper-2 cells, and B lymphocytes, is thought to play a potential pathogenetic or therapeutic role in a number of human conditions, such as inflammation, autoimmunity and cancer.	23679256
Dermatitis	Altered Intercellular Communication	flowers extract against skin inflammation: antioxidant, anti-inflammatory and matrix metalloproteinases inhibitory activities.	23680157
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Associations between markers of inflammation and survival from lung cancer have been observed.	23680692
Inflammation, Hemorrhage, Sensorineural Hearing Loss (disorder)	Altered Intercellular Communication	Use of 3D-FLAIR MRI at 3 T may contribute to the elucidation of pathologic conditions in the inner ears of patients with ISSNHL and provide new radiologic indicators (mild hemorrhage, acute inflammation, presence or absence of BLB breakdown) that might assume the role of prognostic factors.	23681028
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	Our data suggest that FENO is a good surrogate marker of eosinophilic inflammation in COPD patients with exacerbations.	23681903
Myositis	Altered Intercellular Communication	Heightened muscle inflammation susceptibility may impair regenerative capacity in aging humans.	23681911
Myositis	Altered Intercellular Communication	We show for the first time that human aging is associated with muscle inflammation susceptibility (i.e., higher basal state of proinflammatory signaling) that is present in both tissue and isolated myogenic cells and likely contributes to the impaired regenerative capacity of skeletal muscle in the older population.	23681911
Inflammation, Cerebral white matter structure, Immune Reconstitution Inflammatory Syndrome, Meningitis, Cryptococcal	Altered Intercellular Communication	Cryptococcal meningitis accompanying lymphocytic inflammation predominantly in cerebral deep white matter: a possible manifestation of immune reconstitution inflammatory syndrome.	23683170
Inflammation, Cerebral white matter structure, Immune Reconstitution Inflammatory Syndrome, Meningitis, Cryptococcal	Altered Intercellular Communication	This is the first report of a case suggesting that cryptococcal meningitis can accompany lymphocytic inflammation predominantly in cerebral deep white matter as a possible manifestation of immune reconstitution inflammatory syndrome.	23683170
Inflammation, Prostatic Diseases, Benign prostatic hypertrophy	Altered Intercellular Communication	Effects of Serenoa repens, selenium and lycopene (Profluss(r)) on chronic inflammation associated with benign prostatic hyperplasia: results of "FLOG" (Flogosis and Profluss in Prostatic and Genital Disease), a multicentre Italian study.	23683667
Acute and chronic inflammation	Altered Intercellular Communication	To evaluate the efficacy of Profluss(r) on prostatic chronic inflammation (PCI).	23683667
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	The association of C-reactive protein, hypertension, and smoking with PWT is consistent with a role for inflammation or oxidative stress in determining treadmill walking performance.	23684414
Inflammation, Injury of bile duct	Altered Intercellular Communication	One theory regarding etiology is that bile duct injury is due to virus-induced autoreactive T cell-mediated inflammation.	23685050
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Regulatory T cell (Treg) abnormalities in BA could result in unchecked bystander inflammation and autoimmunity targeting bile ducts.	23685050
Inflammation, Anemia, Lupus Erythematosus, Systemic	Altered Intercellular Communication	As SLE is often associated with anaemia, we considered this factor in order to know whether RDW is related with inflammation, anaemia or both in SLE.	23686089
Inflammation, Anemia, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Our results indicate that SLE patients show higher RDW irrespectively of anaemia status, and that RDW is influenced by both anaemia and inflammation, but the influence of anaemia is stronger.	23686089
Airway structure	Altered Intercellular Communication	"Extended" (multiple-flow) measurements of exhaled nitric oxide (FeNO) potentially can distinguish proximal and distal airway inflammation, but have not been evaluated previously in large populations.	23687084
Airway structure	Altered Intercellular Communication	J'awNO and conventional FeNO provide similar information, probably reflecting proximal airway inflammation.	23687084
Inflammation, Demyelination, Nerve Degeneration	Altered Intercellular Communication	Although inflammation appears to play a role in their formation, the mechanisms leading to demyelination and neurodegeneration are poorly understood.	23687122
Inflammation, Meningitis, Nerve Degeneration, Chronic purulent otitis media, B-Cell Lymphomas, Rasmussen subacute encephalitis, Tuberculosis, Meningeal, Chronic inflammatory disorder, MS gene	Altered Intercellular Communication	In our study, we showed that the combination of inflammation, plaque-like primary demyelination and neurodegeneration in the cortex is specific for multiple sclerosis and is not seen in other chronic inflammatory diseases mediated by CD8-positive T cells (Rasmussen's encephalitis), B cells (B cell lymphoma) or complex chronic inflammation (tuberculous meningitis, luetic meningitis or chronic purulent meningitis).	23687122
Inflammation, dupilumab	Altered Intercellular Communication	Dupilumab reduced biomarkers associated with Th2-driven inflammation.	23688323
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with TH2-dominant inflammation.	23688414
Inflammation	Altered Intercellular Communication	TSLP and its metabolic products might play an important role in the inflammation seen in patients with CRSwNP.	23688414
Tumor necrosis, Inflammation	Altered Intercellular Communication	A simple additive index of serum interleukin-6 and soluble tumor necrosis factor-a receptor-1 best captures the effect of chronic inflammation on mortality in older adults among the 15 biomarkers measured.	23689826
Inflammation, Carcinogenesis	Altered Intercellular Communication	Many studies suggest that inflammation and pro-inflammatory factors may play a role in the carcinogenesis with an involvement of the transcription factor NF-kappaB which activity can be controlled by various environmental factors, including many cytokines.	23690221
Metabolic Syndrome X, Cardiovascular system	Altered Intercellular Communication	We measured eight risk factors: the metabolic syndrome, its five components, insulin resistance and cardiovascular inflammation.	23691005
Inflammation, Complex Regional Pain Syndromes	Altered Intercellular Communication	Inflammation appears to play a role in CRPS as, for example, cytokines (like TNF-a) are involved in the affected limb.	23692303
Inflammation, Complex Regional Pain Syndromes	Altered Intercellular Communication	The ongoing inflammation is probably responsible for the central sensitization that sometimes occurs in CRPS.	23692303
Inflammation	Altered Intercellular Communication	Thus, early start of a TNF-a antagonist may counteract inflammation, thereby preventing rest damage and leading to recovery of the disease.	23692303
Inflammation, Granulation finding, Nonspecific interstitial pneumonia	Altered Intercellular Communication	The degree of inflammation and granulation tissue were milder in AEF than in UIP and NSIP and CLE showed milder inflammatory cells than AEF.	23692421
Inflammation, Claudication (finding)	Altered Intercellular Communication	Monitored daily ambulatory activity, inflammation, and oxidative stress in patients with claudication.	23695338
Inflammation, Peripheral Arterial Diseases	Altered Intercellular Communication	We determined the association between daily ambulatory activity and markers of inflammation and oxidative stress in patients with peripheral artery disease (PAD) and claudication.	23695338
Inflammation, MS gene, Trauma, Nervous System	Altered Intercellular Communication	Normal-appearing white matter and GM, despite seeming normal in conventional magnetic resonance imaging (MRI), are important loci of widespread inflammation, neuronal damage, and source of progressive disability in multiple sclerosis (MS).	23695433
Granulomatous inflammation, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	The histological examination of a turbinectomy revealed a granulomatous inflammation with non-caseating granulomas.	23695850
Inflammation, Uveitis	Altered Intercellular Communication	One of her main symptoms was significant uveitis with a pronounced inflammation in the anterior chamber.	23695850
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Systemic inflammation and oxidative stress are the most important features of chronic obstructive pulmonary disease (COPD).	23697277
ARCN1 gene	Altered Intercellular Communication	The presence of oxidative stress in the airways of smokers, the largest population of COPD patients, is a consequence of direct inhalation of cigarette smoke and increased inflammation-related production of reactive oxygen species.	23697277
Inflammation	Altered Intercellular Communication	On the other hand, oxidative stress appears to be the key component of many processes associated with chronic inflammation.	23697277
ARCN1 gene	Altered Intercellular Communication	We showed an increase of serum CRP and GGT values in COPD patients, and we suggest that serum GGT activity might also represent an inflammation/oxidative stress marker.	23697277
Inflammation, Uveitis	Altered Intercellular Communication	Postsurgical uveitis was defined as persistent inflammation for >= 6 months after surgery.	23697858
Inflammation, Lung diseases	Altered Intercellular Communication	Glucose transporter-1 distribution in fibrotic lung disease: association with [18F]-2-fluoro-2-deoxyglucose-PET scan uptake, inflammation, and neovascularization.	23699745
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Thus, FDG-PET scan may detect inflammation and neovascularization in lung fibrosis.	23699745
Chronic sinusitis	Altered Intercellular Communication	Chronic rhinosinusitis is a common inflammatory condition in western countries.	23700266
Anorexia	Altered Intercellular Communication	Whether the association between dietary protein intake and survival is causal or a consequence of anorexia secondary to protein-energy-wasting/inflammation or other factors should be explored in interventional trials.	23700345
Inflammation	Altered Intercellular Communication	The main incriminated mechanisms are the iron deficiency and the chronic inflammation.	23700874
Inflammation, Anemia	Altered Intercellular Communication	The main cause identified was mixed type anemia, followed by iron deficiency and inflammation.	23700874
methyldopa, Inflammation, Retina, Lesion of retina	Altered Intercellular Communication	This study shows the role of oxidative stress and inflammation in retinal structural lesions in AMD and the importance of blood markers in early detection of oxidative stress and thus of retinal lesions in this disease.	23700902
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Inflammation and activation of the neuroendocrine systems comprise important aspects of stroke pathophysiology.	23701638
Inflammation, Fracture, Osteoporosis	Altered Intercellular Communication	It has been suggested that inflammation may have a role in osteoporosis and subsequent fracture risk.	23702388
Inflammation, Malignant neoplasm of endometrium	Altered Intercellular Communication	Chronic inflammation may be important in endometrial cancer etiology.	23702681
Epithelial Damage, Inflammation	Altered Intercellular Communication	Biopsies were evaluated for specific changes in the following general categories: acute inflammation, chronic inflammation, epithelial damage, and architectural distortion.	23702713
Inflammation, Blood Clot, Fracture	Altered Intercellular Communication	The pathologic changes are those of organizing thrombus with and without inflammation with minor complications of foot and strut fracture.	23703961
Pruritus, Purpura, Orbital Pseudotumor, Subconjunctival hemorrhage	Altered Intercellular Communication	A middle aged female patient presented with generalised palpable purpura associated with intense pruritus along with subconjunctival haemorrhage and orbital inflammation.	23704433
palladium, Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	Gingival inflammation (simplified gingival index, GI-S), plaque levels (plaque control record index, PCR), bleeding on probing (BOP) and probing depth (PD), were recorded for all participants before and after IVF.	23705534
Chronic lymphocytic inflammation, Pontine structure, Clippers	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) was first described in 2010 by Pittock and colleagues.	23706003
Inflammation, Amyloidosis	Altered Intercellular Communication	This suggests that chronic stimulation and inflammation of the skin lining the external auditory canal induced amyloidosis.	23706305
Communicable Diseases	Altered Intercellular Communication	These outcome differences in postpubertal children may reflect a hormonal influence on the response to infection or differences in underlying comorbidities, source of infection, or behavior.	23706357
Takayasu Arteritis	Altered Intercellular Communication	Takayasu arteritis is a rare, chronic idiopathic, occlusive inflammation of the aorta and its major branches.	23709154
Inflammation	Altered Intercellular Communication	Precancerous conditions which included polyps and non-specific bowel inflammations were observed in 491 and 52 patients, respectively.	23709378
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	HIV-infected patients are at increased risk for cardiovascular disease, which may be mediated in part by inflammation.	23709436
Hormone abnormality, Hypopituitarism	Altered Intercellular Communication	A detailed clinical history and a careful physical examination in children presenting with multiple clinical signs of hypopituitarism may lead to a timely diagnosis, avoiding clinical morbidity associated to untreated hormonal abnormalities.	23709551
Inflammation	Altered Intercellular Communication	The long-term ventilation and drainage disorder and recurrent inflammation attack may play an important role in occurrence, development and prognosis of MD.	23710863
Nasal inflammation, MS4A2 wt Allele	Altered Intercellular Communication	In addition, persistent nasal inflammation appears to increase the risk of BHR only in the presence of atopy.	23710946
Inflammation, Heart failure	Altered Intercellular Communication	Red cell distribution width is associated with physical inactivity and heart failure, independent of established risk factors, inflammation or iron metabolism; the EPIC-Norfolk study.	23711445
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Single nucleotide polymorphisms (SNPs) of EPHX2 alter sEH activity and are associated with increased [rs41507953 (K55R)] or reduced [rs751141 (R287Q)] cardiovascular risk via modulation of fibrosis, inflammation or cardiac ion channels.	23711456
Inflammation, HIV Infections, Atherosclerosis	Altered Intercellular Communication	Our findings suggest that HIV infection impairs endothelial function and predisposes to atherosclerosis through chronic inflammation and subsequent accumulation of ADMA.	23711612
Inflammation, Ventricular hypertrophy	Altered Intercellular Communication	Low grade inflammation and ECG left ventricular hypertrophy in urban African males: The SABPA study.	23711691
Hypernatremia, Inflammation, Left Ventricular Hypertrophy	Altered Intercellular Communication	Therefore, a novel investigation aimed to assess whether inflammation and pressure overload would have an additive association with ECG left ventricular hypertrophy (LVH).	23711691
Inflammation, Congenital Abnormality	Altered Intercellular Communication	Hyperdynamic blood pressure and inflammation acted in tandem as possible promoting factors to structural wall abnormalities in African men.	23711691
Inflammation, Nasal Polyps	Altered Intercellular Communication	Total and antigen- (fungi, mites and staphylococcal enterotoxins) specific IgEs in nasal polyps is related to local eosinophilic inflammation.	23711866
Inflammation, Nasal Polyps	Altered Intercellular Communication	Total and specific immunoglobulin E (IgE) in nasal polyps (NP) is related to local eosinophilic inflammation.	23711866
Inflammation	Altered Intercellular Communication	Local total IgE and antigen (fungi, mites and SEs)-specific IgEs in NP are related to the local eosinophilic inflammation of AFRS and CRSwNP.	23711866
TNF protein, human, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	This occurred despite high levels of B cell-intrinsic inflammation (TNF-a) in T2D patients, which was surprising as we had previously demonstrated this negatively impacts B cell function.	23711934
UBC protein, human, Inflammation, Malignant neoplasm of urinary bladder, Carcinoma of bladder	Altered Intercellular Communication	Here, we demonstrate that with the increased sensitivity of modern FTIR spectrometers, automatisation of sample preparation and modern bioinformatics, it is possible to identify and validate spectral biomarker candidates for distinguishing between urinary bladder cancer (UBC) and inflammation in suspected bladder cancer patients.	23712384
Inflammation, Swelling	Altered Intercellular Communication	Included cases presented with recurrent inflammation and swelling of a single major salivary gland, without identifiable etiology on examination and imaging.	23712592
Inflammation, Weight decreased	Altered Intercellular Communication	Clinicians concerned about inflammation and cardiovascular risk should recommend weight loss diets most likely to succeed for their patients.	23712970
Inflammation	Altered Intercellular Communication	There was evidence of inflammation in his right calcaneus and toe walking was noted.	23713331
Inflammation, Diplopia, Extraocular, Cysticercosis, Exophthalmos	Altered Intercellular Communication	Orbital cysticercosis commonly presents with signs of inflammation, diplopia, restricted extraocular motility and proptosis.	23713340
Orchitis, Tenosynovitis	Altered Intercellular Communication	When individual components of the PsAMRIS were evaluated, intra- and inter-reader agreement was poor to moderate, especially for tenosynovitis and periarticular inflammation.	23713482
Degenerative polyarthritis, Inflammation, Arthritis, Collagen Diseases	Altered Intercellular Communication	Patients were familiar with many of the terms such as arthritis, osteoarthritis, rheumatism, inflammation, etc.	23713971
Inflammation, Periodontal Route of Administration	Altered Intercellular Communication	Vegetarians revealed better periodontal conditions (less inflammation signs, less periodontal damage and a better dental home care).	23714722
Inflammation, Postoperative Complications	Altered Intercellular Communication	The most common postoperative complication was infection/inflammation (n = 12).	23714988
polyps, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Systemic steroid treatment is effective not only in decreasing polyp size but also in controlling mucosal inflammation.	23715001
Inflammatory abnormality of the eye, Corneal dystrophy, Corneal Diseases	Altered Intercellular Communication	Corneal dystrophy is defined as bilateral and symmetric primary corneal disease, without previous associated ocular inflammation.	23715139
Granulomatous inflammation, Syndrome	Altered Intercellular Communication	Cord colitis syndrome: a cause of granulomatous inflammation in the upper and lower gastrointestinal tract.	23715165
Chronicity, Granulomatous inflammation	Altered Intercellular Communication	CCS exhibits a peculiar histopathologic appearance, as it commonly manifests as granulomatous inflammation involving the upper and lower gastrointestinal tract, with features of chronicity in the colon.	23715165
Inflammation	Altered Intercellular Communication	Endoscopic biopsies of the stomach and colon revealed granulomatous inflammation, consisting of scattered ill-defined aggregates of epithelioid histiocytes, with associated mild neutrophilic inflammation and mildly increased epithelial cell apoptosis.	23715165
Granulomatous inflammation, Epithelial	Altered Intercellular Communication	In the colon, the granulomatous inflammation was associated with surface epithelial injury (including surface erosions) and contained occasional multinucleated epithelioid giant cells.	23715165
Inflammation, Neutrophilic urticaria	Altered Intercellular Communication	Neutrophilic urticaria with systemic inflammation: a case series.	23715523
Inflammation, Urticaria, Connective Tissue Diseases, Malignant Neoplasms	Altered Intercellular Communication	We describe 2 patients having neutrophilic urticaria with systemic inflammation (NUSI) without known connective tissue disorder or malignancy.	23715523
Inflammatory, Inflammation	Altered Intercellular Communication	We therefore sought to model the relationship between systemic inflammatory illness and lipid levels using C-reactive protein (CRP) as the prototypical marker of inflammation.	23716069
Edema, Cardiac, Myocardial	Altered Intercellular Communication	Myocardial oedema on CMR is a characteristic feature of acute TT-CMP, which reflects acute inflammation and acute myocardial injury.	23716287
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	However, the existence of T-cell-driven inflammation in human hypertension has not been confirmed.	23716586
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Immunosenescent CD8(+) T cells and C-X-C chemokine receptor type 3 chemokines are increased in human hypertension, suggesting a role for T-cell-driven inflammation in hypertension.	23716586
Presenile dementia	Altered Intercellular Communication	Since GQ1ba is present in the cerebral cortex and hippocampus, the presence of anti-GQ1ba antibodies may play an important role in disrupting cholinergic synaptic transmission and may participate in the pathogenesis of dementia.	23717411
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	However, the relationship between peritoneal inflammation, peritoneal transport properties and hypoalbuminaemia has not been fully elucidated.	23718260
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	Hypoalbuminaemia was attributable to both the increased peritoneal permeability and systemic inflammation, and intraperitoneal inflammation might contribute to developing these complications.	23718260
Inflammation	Altered Intercellular Communication	Endoscopy revealed severe inflammation and ulcerations of the entire colon.	23720057
Facioscapulohumeral muscular dystrophy 1a, Muscular Dystrophy, Facioscapulohumeral, Autosome	Altered Intercellular Communication	Magnetic resonance imaging of muscle shows short tau-inversion recovery (STIR) brightness in autosomal dominant facioscapulohumeral muscular dystrophy (FSHD1) suggestive of active inflammation/injury.	23720194
Inflammation, Saint Lucia, Colitis	Altered Intercellular Communication	a layer of subepithelial collagen band >= 10 mm in collagenous colitis (CC) with concomitant inflammation and at least 20 lymphocytes per 100 epithelial cells in lymphocytic colitis (LC).	23721118
Tubulitis Assessment, Viremia, Interstitial inflammation	Altered Intercellular Communication	The tubulitis score, extent of tubules with intraepithelial lymphocytes, and interstitial inflammation significantly increased from the time of increasing to decreasing viremia.	23721552
Inflammation, Postoperative infection, Malignant neoplasm of gastrointestinal tract	Altered Intercellular Communication	Correlation between preoperative systemic inflammation and postoperative infection in patients with gastrointestinal cancer: a multicenter study.	23722282
Inflammation, Postoperative infection, Malignant neoplasm of gastrointestinal tract	Altered Intercellular Communication	Our aim was to examine the association between postoperative infection and preoperative systemic inflammation in patients undergoing resection of gastrointestinal cancer.	23722282
Inflammation, Postoperative infection, Malignant neoplasm of gastrointestinal tract	Altered Intercellular Communication	Preoperative systemic inflammation is associated with postoperative infection in patients undergoing resection of gastrointestinal cancer.	23722282
malignant disease, Inflammation	Altered Intercellular Communication	It is well-known that the plasma level of group IIA phospholipase A2 (sPLA2-IIA) is increased in patients with malignant diseases, but whether the up-regulated enzyme expression is directly related to tumorigenesis or a consequence of tumor-associated inflammation remains unresolved.	23722320
Inflammation, Neurogenic Inflammation	Altered Intercellular Communication	Molecular imaging of neuroinflammation can be instrumental in the management of NORSE by guiding placement of intracranial electrodes or assessing the extent and severity of inflammation for antiinflammatory interventions.	23724839
Renal Insufficiency, Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Previous studies have shown that either metabolic syndrome (MetS) or chronic inflammation is related to renal impairment.	23725496
Proteinuria, Inflammation, Damage	Altered Intercellular Communication	Proteinuria (P) is a early sign of inflammation and renal damage.	23726637
Communicable Diseases, Virus Diseases, Myositis, CTCAE 5.0, Myositis	Altered Intercellular Communication	Although no infectious etiology was found, it seems that this semiological entity is a form of benign acute myositis (BAM), a benign muscular inflammation, arising from viral infection and occurring in school-age children, more frequently in males, between 6 and 12 years of age.	23726681
Multiple Organ Failure, Inflammation	Altered Intercellular Communication	Heatstroke (HS) is a life-threatening condition, manifested by systemic inflammation and multiorgan failure.	23726745
Dental Plaque	Altered Intercellular Communication	The plaque formation/morphology may depend on local environment and is independent of oxidative stress/inflammation observed on the level of the whole body.	23726810
TNF protein, human, Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	We compared systemic inflammatory profiles in CRC (n=99), health (n=98), high CRC-risk conditions (n=48) and overt inflammation (n=69) by multiplexed analysis of IL-1b, IL-6, IL-8, FGF-2, G-CSF, GM-CSF, MCP-1, MIP-1a, TNF-a, VEGF-A, and PDGF-B and CEA.	23726839
Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Diabetes Mellitus, Non-Insulin-Dependent, Hepatitis	Altered Intercellular Communication	In this phase 2 trial, administration of 25 or 50 mg OCA for 6 weeks was well tolerated, increased insulin sensitivity, and reduced markers of liver inflammation and fibrosis in patients with type 2 diabetes mellitus and nonalcoholic fatty liver disease.	23727264
Inflammation, Primary malignant neoplasm, Pathology, Diabetes Mellitus, Heart Diseases	Altered Intercellular Communication	This range of pathologies include general signs of premature aging, neuro-muscular dysfunctions, cancer, diabetes, various heart diseases, inflammation and other conditions not previously known to be related to mitochondrial function.	23727386
Inflammation, Disease	Altered Intercellular Communication	Analysis of the most increased (>=1.5 fold) and decreased (<=0.8 fold) proteins in the keratoconus corneal epithelial protein extracts identified proteins related to dermal diseases, inflammation, epithelial stratification and mesenchymal changes.	23727491
Communicable Diseases, Weight decreased, Pneumonitis	Altered Intercellular Communication	After infection with diverse strains of H1N1 influenza, treated mice showed minimal weight loss and lung inflammation.	23728362
Intraocular inflammation, Endophthalmitis, CTCAE	Altered Intercellular Communication	Endogenous endophthalmitis is a sight-threatening condition caused by microorganisms crossing the blood-ocular barrier and inducing profound intraocular inflammation.	23728762
Thyroid carcinoma	Altered Intercellular Communication	High serum thyroid-stimulating hormone (TSH) is associated with thyroid carcinoma in patients with thyroid nodules.	23728859
Diabetes Mellitus, Insulin-Dependent, Inflammation, Cardiomyopathies, Monogenic autoinflammatory syndrome	Altered Intercellular Communication	Pigmentary hypertrichosis and non-autoimmune insulin-dependent diabetes mellitus (PHID) syndrome is associated with severe chronic inflammation and cardiomyopathy, and represents a new monogenic autoinflammatory syndrome.	23729543
Inflammation, Cardiomyopathies	Altered Intercellular Communication	We report a new association of PHID syndrome with severe systemic inflammation, scleroderma-like changes, and cardiomyopathy.	23729543
Inflammation, Liver Dysfunction	Altered Intercellular Communication	Laboratory data showed mild inflammation and no liver or renal dysfunction.	23729712
Inflammation, Damage	Altered Intercellular Communication	At the same level of inflammation, the prognosis regarding joint damage is believed to be different for anticitrullinated protein antibody (ACPA)-negative and ACPA-positive patients.	23729803
Inflammation, Damage	Altered Intercellular Communication	At the same level of inflammation, ACPA-negative patients have less joint damage and lower probability for damage in newly affected joints than ACPA-positive patients.	23729803
Inflammation, Arthritis, Polyarthritis	Altered Intercellular Communication	To compare Doppler ultrasound (US) and 3.0-Tesla magnetic resonance imaging (3.0-T MRI) findings of synovial inflammation in the tendons and joints in an early polyarthritis cohort (patients who presented < 1 year after arthritis onset) using a bilateral hand and wrist evaluation.	23729806
Inflammatory abnormality of the eye	Altered Intercellular Communication	Decreased levels of tear IL-10, an anti-inflammatory cytokine, may lead to an inflammatory ocular surface environment, exacerbate ocular surface inflammation, and deteriorate tear function tests.	23730902
Rosacea, Inflammatory abnormality of the eye	Altered Intercellular Communication	A bigger sample size, including rosacea patients with corneal involvement, is needed to confirm the role of cytokines in the pathogenesis of rosacea-associated ocular inflammation.	23730902
Inflammation, Colonization, Acne	Altered Intercellular Communication	Inflammation, increased sebum production and P. acnes colonization are key factors in acne pathogenesis.	23731195
Inflammation, Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	It has been suggested that these symptoms are a reflection of occult inflammation rather than coexisting IBS.	23731196
Inflammation, Coronary Artery Vasospasm, Cardiac Arrhythmia	Altered Intercellular Communication	Intravenous nicorandil infusion dilates the coronary artery and reduces inflammation, coronary spasm, and arrhythmia.	23731922
Inflammation	Altered Intercellular Communication	Inflammation is thought to play a key role in many patients, characteristically with an increase in mast cells within the detrusor muscle of the bladder.	23732167
Inflammation	Altered Intercellular Communication	The IgG4-positive patients were of older age and had increased severe inflammation and decreased bladder capacity as compared with the IgG4-negative patients.	23732167
Barrett Esophagus, Inflammation, Esophagitis	Altered Intercellular Communication	At endoscopy 83% had evidence of chronic inflammation in the distal esophagus on histopathology, including 22% with moderate to severe esophagitis and 7% with Barrett's esophagus.	23732271
Inflammation, Illness (finding)	Altered Intercellular Communication	Because severe inflammation in adults increases CNP, we studied CNP peptides and inflammatory markers in children with acute illness.	23732776
Inflammation, Cardiotoxicity, Cardiovascular Diseases	Altered Intercellular Communication	These findings are important because MHC-Cre mice are widely used in cardiovascular research despite the limitations imposed by Cre-induced cardiac toxicity, and also because inflammation is an important pathological component of many human cardiovascular diseases.	23732814
Inflammation, Cardiac complication, Kidney Diseases, Diabetes Mellitus	Altered Intercellular Communication	Studies in recent years suggest a role for inflammation, proinflammatory cytokines in particular, the development of microvascular complications of diabetes, including nephropathy.	23734508
Airway structure	Altered Intercellular Communication	Relationship between airway pathophysiology and airway inflammation in older asthmatics.	23734667
Airway structure	Altered Intercellular Communication	Airway closure is also greater in older asthmatics, an observation that may be explained by differences in airway inflammation.	23734667
Airway structure, AHR wt Allele, Eosinophilic inflammation, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	We hypothesized that in older adult patients with asthma, neutrophil airway inflammation increases airway closure during bronchoconstriction, while eosinophil airway inflammation increases airway hyperresponsiveness (AHR).	23734667
Airway structure	Altered Intercellular Communication	Airway inflammation was assessed by induced sputum and exhaled nitric oxide (eNO).	23734667
Airway structure, Inflammation	Altered Intercellular Communication	Eosinophilic airway inflammation is associated with AHR while neutrophilic inflammation may be an important determinant of airflow limitation at rest and airway closure during bronchoconstriction.	23734667
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	To evaluate the efficacy of mesalazine suppositories in patients with ulcerative colitis (UC) and rectal inflammation; and in patient groups categorised by the extent of lesions.	23734840
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Mild-to-moderate UC patients with rectal inflammation were randomly assigned either a 1 g mesalazine or placebo suppository.	23734840
Inflammation, Granulomatous, Necrosis	Altered Intercellular Communication	A biopsy of the left temporal lesion showed a granulomatous and angiodestructive inflammation with infiltration of many CD4(+) T-lymphocytes and multinucleated giant cells and with fibrinoid necrosis of the arterial walls in the subarachnoid space.	23735532
Carotid Endarterectomy, Inflammation, Impaired cognition	Altered Intercellular Communication	Inflammation and cognitive dysfunction in type 2 diabetic carotid endarterectomy patients.	23735728
Cerebrovascular Disorders, Inflammation, Impaired cognition, diabetic	Altered Intercellular Communication	Type 2 diabetic patients have a high incidence of cerebrovascular disease, elevated inflammation, and high risk of developing cognitive dysfunction following carotid endarterectomy (CEA).	23735728
Inflammation, Impaired cognition, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	To elucidate the relationship between inflammation and the risk of cognitive dysfunction in type 2 diabetic patients, we aim to determine whether elevated levels of systemic inflammatory markers are associated with cognitive dysfunction 1 day after CEA.	23735728
Acanthosis Nigricans, Inflammation, Obesity	Altered Intercellular Communication	MSC-N showed strong positive genetic correlations with obesity, insulin resistance, inflammation, and acanthosis nigricans, and negative genetic correlation with physical fitness.	23736306
Communicable Diseases, Inflammation, Pathology	Altered Intercellular Communication	Inclusion criteria for the patients were presence of at least 2 mm of bone beyond the root apex, the absence of acute signs of infection or inflammation in the treatment area, and the absence of systemic pathologies that would contraindicate bone healing around implants.	23736310
Inflammation, Cardiac complication, Obesity	Altered Intercellular Communication	Childhood obesity is accompanied by low-grade systemic inflammation, which contributes to the development of insulin resistance and cardiovascular complications later in life.	23736361
Inflammation, Obesity	Altered Intercellular Communication	25(OH)D deficiency in childhood obesity was associated with enhanced systemic inflammation and reduced insulin sensitivity.	23736361
Inflammation, Disease, Orbital Neoplasms	Altered Intercellular Communication	Swelling of the upper eyelid in childhood is caused by a variety of diseases and is very often generated by inflammation but orbital tumors should always be considered in the differential diagnostics.	23736662
Inflammation	Altered Intercellular Communication	Cholecystectomy can become hazardous when inflammation develops, leading to anatomical changes in Calot's triangle.	23736889
Inflammation	Altered Intercellular Communication	The operations were performed laparoscopically irrespective of the grade of inflammation estimated preoperatively.	23736889
Inflammation	Altered Intercellular Communication	However, patients with severe inflammation of the gallbladder underwent LSC involving resection of the anterior wall of the gallbladder, removal of all stones and placement of an infrahepatic drainage tube.	23736889
Inflammation, Adduction	Altered Intercellular Communication	The resulting increase in adduction moment suggests greater medial compartment loads, which may combine with elevated levels of inflammation to contribute to the increased risk of medial OA in this population.	23737249
Infarction, Inflammation, Demyelination, Traumatic injury	Altered Intercellular Communication	Typical causes of internuclear ophthalmoplegia (INO) include arterial infarcts, demyelinating conditions, inflammation and trauma.	23737577
Proctitis	Altered Intercellular Communication	Inflammation mediators related to radiation proctitis are partially elucidated, and neovascularization is thought to play a key role.	23737650
Tissue injury	Altered Intercellular Communication	Our results showed that in postradiation rectal biopsy specimens neoangiogenesis seems to be inflammation-related and constitutes a significant postradiation component of the tissue injury.	23737650
Osteomyelitis, Inflammation	Altered Intercellular Communication	In this article, we report the case of acute pneumococcal osteomyelitis of the humerus in an immunocompetent and otherwise healthy 44-year-old male patient presenting with minor inflammation signs and misleading clinical features.	23738890
Pain Distress Question	Altered Intercellular Communication	Inflammation of lumbar bursae may be responsible for the low back pain reported by patients with PMR.	23739147
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Angiopoietin-like protein 2 (Angptl2) is an adipokine that promotes inflammation and endothelial dysfunction of the vessels.	23739531
Inflammation, Failure, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8	Altered Intercellular Communication	BBDR plasma cytokine levels mirrored the signatures showing early inflammation, followed by induction of a regulated state that correlated with failure of virus to induce T1D in older rats.	23739610
hearing impairment, Inflammation	Altered Intercellular Communication	Long-term assessment of systemic inflammation and the cumulative incidence of age-related hearing impairment in the epidemiology of hearing loss study.	23739996
hearing impairment, Inflammation, Disease	Altered Intercellular Communication	Although research has linked systemic inflammation to various diseases of aging, few studies have examined the potential role it may play in the development of age-related hearing impairment.	23739996
Pain Distress Question, Inflammation, Dyssomnias	Altered Intercellular Communication	Sleep disturbance and pain were found to be most important, although inflammation, as measured by CRP, was also associated.	23740186
Inflammation, Spondylitis	Altered Intercellular Communication	Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation.	23740229
Acute and chronic inflammation	Altered Intercellular Communication	Autophagy but not UPR was required to modulate the expression of IL-23 in isolated LPMCs of AS patients with chronic gut inflammation, CD patients and controls.	23740229
Inflammation, Arthritis	Altered Intercellular Communication	The impact of inflammation on metabolomic profiles in patients with arthritis.	23740368
Inflammation, Arthritis	Altered Intercellular Communication	In early arthritis, we were able to stratify the patients according to the level of current inflammation, with C-reactive protein correlating with metabolic differences in 2 separate groups (P < 0.001).	23740368
Loss, Inflammation	Altered Intercellular Communication	Biopsy of a lumbar dorsal sensory root showed myelinated fiber degeneration and loss, with endoneurial inflammation.	23740462
Inflammation	Altered Intercellular Communication	CTLA-4Ig treatment significantly reduces glandular inflammation in primary SS, induces several cellular changes, and increases saliva production.	23740889
Ischemia, Dryness (characteristic), Inflammation	Altered Intercellular Communication	Wavelet augmented ultrasound is sensitive to the organisational elements of choroidal microarchitecture relating to scatter and fluid tissue boundaries such as seen in ischaemia and inflammation, allowing statistically significant differentiation of dry, wet and non-AMD eyes.	23740965
ARCN1 gene, Inflammation	Altered Intercellular Communication	In addition, patients with mixed granulocytic or neutrophilic stable COPD remained at lower lung functions and higher levels of inflammation.	23741289
Inflammation	Altered Intercellular Communication	Patients with AECOPD display heterogeneous inflammation, and the profiles of sputum inflammatory cells may be used as valuable biomarkers for the classification of AECOPD patients.	23741289
Inflammation	Altered Intercellular Communication	Detection of subclinical synovial inflammation by microwave radiometry.	23741349
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	Of 40 RA and 20 osteoarthritis knees examined, ultrasound findings indicative of subclinical inflammation (fluid effusion and/or Doppler signal) were found in 24 and 12, respectively, in which the temperature was higher than healthy knees and DT was lower (-0.9+-0.7 in RA and -1.0+-0.5 in osteoarthritis versus -1.8+-0.2degC, p<0.001).	23741349
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	The 5 RA knees with power Doppler findings indicative of grade 2 inflammation had a DT 3 times lower compared to healthy (-0.6+-0.6, p = 0.007), whereas the 9 RA and the 7 osteoarthritis knees with additionally fluid effusion, had even lower DT (-0.4+-0.7, p<0.001).	23741349
Arthritis	Altered Intercellular Communication	Using a safe, rapid and easy-to-perform method, such as microwave radiometry, thermal changes within the knee joint may reflect non-clinically apparent joint inflammation.	23741349
Inflammation, Leprosy, Paucibacillary, Hypertrophy	Altered Intercellular Communication	Slow progression of disease, the lack of neural enlargement and the neural biopsies without inflammation suggest that most of these patients could have spontaneously cured PNL, as happens with other cases of paucibacillary leprosy.	23741881
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	By neutralizing CXCL13 in a mouse model of chronic cigarette smoke (CS) exposure, we aimed at interrogating the link between lymphoid follicles and development of pulmonary inflammation, emphysema, and airway wall remodeling.	23742729
Inflammation, Destruction (action)	Altered Intercellular Communication	Neutralization of CXCL13 partially protects mice against CS-induced inflammation in bronchoalveolar lavage and alveolar wall destruction.	23742729
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Fever is an important sign of inflammation recognized by health care practitioners and family caregivers.	23742739
Inflammation	Altered Intercellular Communication	Deficient production of immunomodulatory PGs may promote chronic inflammation and airway remodeling.	23742951
vascular inflammations	Altered Intercellular Communication	The strong negative association between exercise and Lp-PLA2 activity and the fact that the latter resulted to be the unique continuous variable that persisted associated with physical activity would add an additional benefit of exercise in early prevention of vascular inflammation and atherogenesis.	23743170
Inflammation, Neoplasms	Altered Intercellular Communication	There have been several reports that members of the regenerating gene (REG) family are highly expressed in chronic inflammation and in tumors of the digestive organs.	23743605
Inflammation, hepcidin	Altered Intercellular Communication	Hepcidin is a key regulator of iron homeostasis: downregulation in the presence of iron deficiency allows enteral iron resorption, while upregulation in case of chronic inflammation blocks it.	23743883
Inflammation, Impaired T cell function, Hypoxemia, Chronic Kidney Diseases	Altered Intercellular Communication	Nocturnal hypoxemia contributes to systemic inflammation, oxidative stress, endothelial cell dysfunction, and activation of the renin-angiotensin system, which are common pathologic mechanisms of CKD progression.	23744006
Coinfection, Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Coinfection with H. pylori and C. pneumoniae was significantly associated with hypertension compared with double seronegativity after adjustment for age, sex, chronic low-grade inflammation, and cardiovascular risk factors (OR = 1.68; 95% CI = 1.14-2.47; P = 0.008].	23744497
Coinfection, Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	However, coinfection with C. pneumoniae and H. pylori showed a significant association with essential hypertension, independent of cardiovascular risk factors and chronic low-grade inflammation.	23744497
Barrett Esophagus, Inflammation	Altered Intercellular Communication	Barrett esophagus develops in a scenario of chronic inflammation, linked to free radical formation and oxidative DNA damage.	23744553
Inflammation, Axonal loss, Neuronal loss in central nervous system	Altered Intercellular Communication	Peripheral nerve biopsies in 5 patients showed axonal loss without significant inflammation; a dorsal root ganglion biopsy in 1 patient showed neuronal loss and inflammatory infiltrate.	23744601
Inflammation, Granulation finding, Vascular System Injuries	Altered Intercellular Communication	Restenosis after stenting is an over-reaction of the wound-healing response after vascular injury, which is characterized by a sequence of inflammation, granulation, extracellular matrix remodeling, and smooth muscle cell proliferation and migration.	23744617
Inflammation	Altered Intercellular Communication	Endoscopies of the large bowel showed patchy inflammation from the rectum to the hepatic flexure with multiple tiny polyps.	23744856
Inflammation	Altered Intercellular Communication	A 13-year-old girl was initially observed for several months due to elevated sedimentation rate (ESR 75-90 mm/h) without signs of inflammation or other symptoms and disease signs.	23745349
Inflammation, Damage	Altered Intercellular Communication	The patients with more pronounced lung damage in the form of ABPA-CB and ABPA-CB-ORF had higher serological parameters suggestive of increased systemic inflammation.	23745673
Inflammation, Cardiovascular Diseases, Obesity, Blood Glucose	Altered Intercellular Communication	Obesity is a significant health issue worldwide and is associated with chronic, low-grade inflammation predisposing the individual to cardiovascular disease and impaired blood glucose homeostasis.	23746205
Inflammation	Altered Intercellular Communication	Anthocyanins and phenolic acids from purple carrots are effective at reversing inflammation and metabolic alterations in animal models, potentially through inhibition of inflammatory pathways.	23746205
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Histological inflammation and risk of subsequent prostate cancer among men with initially elevated serum prostate-specific antigen (PSA) concentration in the Finnish prostate cancer screening trial.	23746332
Inflammation, Prostate carcinoma, Structure of posterior cerebral artery	Altered Intercellular Communication	To assess whether histological signs of inflammation are associated with an increased risk of subsequent prostate cancer (PCa) in men with elevated serum prostate-specific antigen (PSA) concentrations and benign initial biopsy.	23746332
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Histological inflammation in a prostate biopsy among men with an initial false-positive screening test was not associated with an increased risk of subsequent PCa, but instead with a decreased risk which was of borderline significance.	23746332
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Inflammation in prostate biopsy is not a useful risk indicator in PCa screening.	23746332
HD Term Type, Inflammation	Altered Intercellular Communication	We have recently shown that 1 year of pomegranate juice (PJ) intake attenuated OS and inflammation in patients with HD.	23746559
Inflammation	Altered Intercellular Communication	Degranulation of PMNLs leads to the release of other cell moieties, such as inflammatory mediators and proteases that enhance inflammation.	23746559
Inflammation	Altered Intercellular Communication	We conclude that PJ intake attenuated the increase in systemic OS and inflammation induced by IV iron administration during the dialysis session.	23746559
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Gender differences in the prospective associations of self-reported sleep quality with biomarkers of systemic inflammation and coagulation: findings from the Heart and Soul Study.	23746737
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Systemic inflammation is proposed as a putative mechanism underlying the link between poor sleep and cardiovascular disease.	23746737
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Further research is necessary to elucidate the pathways that underlie gender-specific associations between subjective sleep quality and markers of inflammation and coagulation as this may help clarify gender disparities in CHD.	23746737
Inflammation, atherosclerotic	Altered Intercellular Communication	Leukotrienes are involved in the physiological mechanism of atherosclerotic events and inflammation.	23746795
Vascular Diseases, Inflammation, Neoplasms, GCA gene, Giant Cell Arteritis, Pituitary Apoplexy, Brain Infarction	Altered Intercellular Communication	In the group of patients who had vasculopathic risk factors only, with no other significant medical condition, 10% of patients (8/80) were found to have other causes, including midbrain infarction, neoplasms, inflammation, pituitary apoplexy, and giant cell arteritis (GCA).	23747163
Communicable Diseases, Inflammation	Altered Intercellular Communication	The data from this study showed that immunosuppression, the shift of the Th1/Th2 balance toward a Th2 response, increased Tregs, and related inflammatory cytokines are involved in the complex process of inflammation and infection caused by gut mucosal barrier dysfunction in patients with early SAP.	23747854
Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	The Plaque and Bleeding indices of both groups were comparable, and peri-implant inflammation scores in both groups were zero for all implants.	23748315
Inflammation, Thrombosis, Swelling, Body fluid retention, Achromia of skin	Altered Intercellular Communication	The method is efficient only in those pathological processes accompanied by variable skin depigmentation, water retention, inflammation, thrombosis, or swelling.	23748801
Chronicity, Granulomatous inflammation, Metaplasia, Chronic Active Colitis	Altered Intercellular Communication	CCS is histologically characterized by chronic active colitis with granulomatous inflammation and Paneth cell metaplasia suggesting chronicity.	23749110
Colitis, Cytomegaloviral colitis, Granulomatous inflammation, Metaplasia, Chronic Active Colitis, Graft-vs-Host Disease	Altered Intercellular Communication	Chronic active colitis with granulomatous inflammation and Paneth cell metaplasia was present in 12/33 (36%) patients with biopsy-proven GVHD, 4/6 (67%) patients with CMV colitis and 2/15 (13%) patients with nonspecific colitis.	23749110
Proteinuria, Nephritis, MPV17 gene, Kidney Diseases	Altered Intercellular Communication	MDM2 blockade with nutlin-3a could be a novel therapeutic strategy to prevent renal inflammation, podocyte loss, glomerulosclerosis, proteinuria, and progressive kidney disease.	23749457
Inflammation	Altered Intercellular Communication	Remission was defined as absence of clinically detectable joint inflammation on a 51-joint count.	23749581
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Systemic inflammation, as evidenced by the Glasgow prognostic score (GPS), predicts cancer-specific survival in various types of cancer.	23749931
Inflammation, Lymphoma	Altered Intercellular Communication	IgG4-related inflammation of the orbit simulating malignant lymphoma.	23749941
Inflammation, B-Cell Lymphomas	Altered Intercellular Communication	We report a case of IgG4-related inflammation of the orbit simulating extranodal marginal zone B-cell lymphoma (EMZL).	23749941
Inflammation, Neoplasms	Altered Intercellular Communication	Based on the clinicopathological findings, tumors 1 and 2 were diagnosed as IgG4-related inflammation and EMZL, respectively.	23749941
Airway structure, Asthma	Altered Intercellular Communication	It has been reported that fractioned exhaled nitric oxide (FENO) can be used for monitoring airway inflammation and for asthma management but conclusions drawn by different researchers are controversial.	23756211
Inflammation, Tumor necrosis, Colorectal Carcinoma	Altered Intercellular Communication	Cancer-associated inflammation, in the form of local and systemic inflammatory responses, appear to be linked to tumour necrosis and have prognostic value in patients with colorectal cancer.	23756867
Inflammation, Diabetes Mellitus, Insulin-Dependent, Destruction of tissue	Altered Intercellular Communication	The extent of periodontal inflammation and tissue destruction and the serum levels of sRANKL (pg/ml) and OPG (pg/ml) were determined in 80 subjects with type 1 diabetes mellitus (T1DM).	23758409
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome and abdominal fat are associated with inflammation, but not with clinical outcomes, in peritoneal dialysis patients.	23758640
Inflammation	Altered Intercellular Communication	In conclusion, these results suggest that BuChE enzymatic activity plays an important role in regulating intrinsic inflammation and activity of cholinoceptive glial cells and that this might be of clinical relevance.	23759148
Lymphoplasmacytic Infiltrate, Orbital Pseudotumor	Altered Intercellular Communication	High prevalence of IgG4-related lymphoplasmacytic infiltrative disorder in 25 patients with orbital inflammation: a retrospective case series.	23759440
Orbital Pseudotumor	Altered Intercellular Communication	25 patients with biopsy-proven idiopathic orbital inflammation examined from January 2006 through December 2011 were included.	23759440
Orbital Pseudotumor	Altered Intercellular Communication	Finally, 40% of patients with biopsy-proven orbital inflammation were classified as IgG4-RD, with typical histological features, but without specific clinical or radiological findings.	23759440
Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	It is well known that inflammation plays a key role in both initiation and propagation of acute coronary syndrome (ACS).	23760114
Inflammation	Altered Intercellular Communication	The inflammation assessed using WBC and its subtypes may be more important in young NSTE-ACS patients.	23760114
Vasculitis, Inflammation, Lupus Erythematosus	Altered Intercellular Communication	The implication of the idea that subclinical vessel inflammation is widespread in patients with lupus-and that this inflammation confers a significant part of the patients' risk of accelerated atherosclerosis-might be a lowering of the threshold for aggressive disease-modifying treatment of lupus, essentially a "treat-to-target" approach to systemic lupus.	23761181
Inflammation, Tuberculosis, Unknown (origin) (qualifier value), Electrocardiogram: myocardial infarction (finding), Pericarditis, Constrictive, Uremia	Altered Intercellular Communication	Aetiology of constrictive pericarditis was idiopathic in 49 patients (55%), prior cardiac surgery in 21 patients (23.6%), tuberculosis in 5 patients (5.6%), radiation treatment in 5 (5.6%), uraemia in 4 (4.5%), inflammation in 3 (3.5%) myocardial infarction in 2 (2.2%), and perioperative mortality was 7%.	23761416
Inflammation, Scleritis, Eye pain	Altered Intercellular Communication	Scleritis is an inflammation of the outer eye coating that manifests with redness and ocular pain, and tends to be more severe when associated with a systemic collagen disease.	23761504
Inflammation, Muscular Atrophy, Skeletal muscle structure	Altered Intercellular Communication	Systemic and tissue inflammation also accelerates skeletal muscle loss, but it is unknown whether inflammation is associated to inactivity-induced muscle atrophy in healthy older adults.	23761639
Inflammation, Prostate, Benign prostatic hypertrophy	Altered Intercellular Communication	We conclude that the signal detected by the nanodevice, in contrast to individual targets detected with antibodies used in this study, originates from multiple thioredoxin interacting protein partners that distinguish the M2 neutrophil and macrophage associated inflammatory response in prostate cancer-associated stroma from the CD4+ T-Lymphocyte linked inflammation in benign prostatic hyperplasia.	23762225
Inflammation, Asthma	Altered Intercellular Communication	Association of eosinophilic inflammation with FKBP51 expression in sputum cells in asthma.	23762334
Inflammation, Asthma	Altered Intercellular Communication	To evaluate the relationship between eosinophilic inflammation and FKBP51 expression in sputum cells in asthma.	23762334
Inflammation, Asthma	Altered Intercellular Communication	Lower FKBP51 expression in sputum cells may reflect eosinophilic inflammation and glucocorticoid responsiveness in steroid-naive asthmatic patients.	23762334
Inflammation, Cardiac complication, Diabetes Mellitus	Altered Intercellular Communication	Adaptive immunity, inflammation, and cardiovascular complications in type 1 and type 2 diabetes mellitus.	23762872
Inflammation	Altered Intercellular Communication	In our study, we investigated the role of systemic inflammation and T-cell subsets in T1- and T2DM and the possible mechanisms underlying the increased cardiovascular risk associated with these diseases.	23762872
Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints affecting multiple organs in the body.	23763224
Inflammation, Fibrosis Assessment, Branchioma, Necrosis	Altered Intercellular Communication	On the pathology report the pericardial mass resection showed mild chronic inflammation, extensive fibrosis, fat necrosis and branchial cyst surrounded with mild chronic inflammation.	23763224
Airway structure	Altered Intercellular Communication	However, abnormally elevated ATP levels have been reported in inflamed airways, suggesting that excessive ATP in ASL contributes to airway inflammation.	23763446
Airway structure, Fibrosis Assessment	Altered Intercellular Communication	In this study, links between cystic fibrosis (CF)-associated airway inflammation and airway epithelial ATP release were investigated.	23763446
Airway structure	Altered Intercellular Communication	We propose that CF airway inflammation up-regulates the capacity of airway epithelia to release ATP via Ca(2+)-dependent vesicular mechanisms not associated with mucin granule secretion.	23763446
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We investigated whether the effect of inflammation on C-reactive protein (CRP) and ferritin levels is being overlooked in indigenous patients with chronic kidney disease.	23763720
Inflammation, Hepatobiliary Disorder, Autoimmune Chronic Hepatitis, Insemination, Artificial, Homologous	Altered Intercellular Communication	Autoimmune hepatitis (AIH) is a chronic liver disease caused by inflammation of the liver.	23763817
Inflammation, Fibrosis Assessment, Neoplasms	Altered Intercellular Communication	It was correlated with tumor progression, but not with the degree of liver fibrosis and inflammation.	23764929
Chronic cholangitis, Inflammation, Primary Biliary Cholangitis	Altered Intercellular Communication	We have reported that fractalkine expression associated with chronic inflammation is observed in the damaged bile ducts and periductal vessels of PBC patients, which is closely associated with chronic cholangitis.	23765258
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	PDE5 inhibitors blunt inflammation in human BPH: a potential mechanism of action for PDE5 inhibitors in LUTS.	23765639
Inflammation	Altered Intercellular Communication	Chronic inflammation is one of the putative links between these diseases.	23765639
Inflammation, Prostate	Altered Intercellular Communication	In this study we investigate whether PDE5i could blunt inflammation in the human prostate.	23765639
Inflammation, Anger	Altered Intercellular Communication	Varieties of anger and the inverse link between education and inflammation: toward an integrative framework.	23766379
social inequality, Inflammation, Anger	Altered Intercellular Communication	To examine multiple aspects of anger experience and expression (frequency, outward expression, suppression, and control) as moderators of the association of social inequality, as measured by educational status, with inflammation and coagulation markers.	23766379
ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	The etiology of chronic obstructive pulmonary disease (COPD) is chronic lung inflammation.	23767419
Inflammation, Fever, CTCAE, Neurologic (qualifier value), Back Pain, Neuralgia	Altered Intercellular Communication	Apart of a chronic neuropathic foot wound, the patients reported severe or deteriorated dorsal pain (2 in the lumbal region, one in thoracic spine), had no new neurologic lesion in the beginning, some had fever, but all had high laboratory parameters of inflammation that did not correlate with local finding on the foot.	23767458
Dysmotility, Gastroparesis, Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The low prevalence of H. pylori infection in gastroparesis could be explained by higher rates of previous eradication, conditions unfavourable to the survival of H. pylori, or a protective effect of mucosal inflammation against the development of motility disorders.	23768443
Inflammation, Malignant neoplasm of larynx, Malignant Neoplasms	Altered Intercellular Communication	Chronic inflammation has been implicated in the pathogenesis of several cancers, including lung and laryngeal cancer.	23768737
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	Microscopic findings revealed micronodular cirrhosis with mixed inflammation in the portal areas.	23769108
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, fibrogenesis	Altered Intercellular Communication	Plasma galectin-3, a mediator of fibrogenesis and inflammation, its potential to associate with type 2 diabetes (T2DM) is poorly investigated.	23769567
Inflammation, anatomical bulb, Hyperemia	Altered Intercellular Communication	Objective tarsal conjunctiva inflammation, bulbar conjunctiva findings (such as hyperemia and thickening), cornea staining, and subjective symptoms were evaluated.	23770977
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We investigated whether such a pattern was also found in biopsies from ingrown toenails, which can be greatly distorted through inflammation and fibrosis.	23771067
Inflammatory abnormality of the eye	Altered Intercellular Communication	The ocular inflammation can be the first symptom of syphilis.	23771257
Primary central nervous system lymphoma, Inflammation, Demyelination, Lymphoproliferative Disorders	Altered Intercellular Communication	Dynamic susceptibility-weighted contrast-enhanced perfusion MRI using ferumoxytol showed low rCBV (ratio <1.0) in 3 cases of demyelination or inflammation, modestly elevated rCBV in 5 cases of CNS lymphoma or lymphoproliferative disorder (range: 1.3-4.1), and no measurable disease in one case.	23771486
Inflammation, Weight decreased, Overweight	Altered Intercellular Communication	To determine the independent effect of long-term physical activity (PA) and the combined effects of long-term PA and weight loss (WL) on inflammation in overweight and obese older adults.	23772804
Inflammation, Chronic granulomatous disease	Altered Intercellular Communication	These findings suggest that elevated BAFF in CGD subjects and healthy donors is a consequence of acute and chronic inflammation.	23773925
Inflammation, Aortitis	Altered Intercellular Communication	Medial inflammation was predominantly lymphohistiocytic and was marked in 3 cases but limited to the region adjacent to the dissection plane, unlike aortitis.	23774175
Inflammation, Traumatic injury, Rupture	Altered Intercellular Communication	Adventitial inflammation is prominent soon after intimal injury in aortic dissections before rupture of the false lumen.	23774175
Inflammation, Aortitis	Altered Intercellular Communication	The pattern of inflammation is distinct from aortitis and can be used to date early aortic dissections.	23774175
Inflammation, Atherosclerosis	Altered Intercellular Communication	Persistent inflammation plays a role in the pathogenesis of atherosclerosis.	23774275
Inflammation	Altered Intercellular Communication	We next delivered the AAVs to mouse brains neurosurgically, and demonstrated that Acat1-targeting AAVs could express viral proteins and effectively diminish ACAT activity in vivo, without inducing appreciable inflammation.	23774792
Inflammation, Fibrosis Assessment, Injury of liver	Altered Intercellular Communication	Experimental liver injury models have indicated that natural killer (NK) cells are critical regulators of inflammation and fibrosis.	23774822
Inflammation, Fibrosis Assessment, Cholestasis	Altered Intercellular Communication	By multiple regression analysis, bile ductular plugs, morphometric assessment of fibrosis, rosetting, portal tract inflammation and pattern of cholestasis were found to be significant in discriminating the two groups.	23775681
Inflammation, Early-onset	Altered Intercellular Communication	Greater inflammation may contribute to the precipitous disease course typically seen in early-onset patients.	23775979
Inflammation, Pouchitis	Altered Intercellular Communication	The natural history of anal transition zone inflammation and possible relationship to pouchitis: a long-term longitudinal study.	23777389
Inflammation, Infection, Immune System Diseases, Uveitis	Altered Intercellular Communication	Specific causes of uveitis included infections (34.4%), with syphilis responsible for 16.4% of all cases, and defined immunological disorders (27.0%); no cause for the inflammation was identified in 34.4% of persons.	23777456
Inflammation, Tuberculosis	Altered Intercellular Communication	Histological examination revealed granulomatouse inflammation with numerous acid fast bacilli consist with tuberculosis.	23777575
Communicable Diseases, Inflammation	Altered Intercellular Communication	(3) and (4) indicate intense inflammation caused by local infection.	23777595
Adenoma, Toxic effect	Altered Intercellular Communication	Genetic polymorphisms in multiple inflammation-related genes appear to interact with celecoxib on adenoma recurrence and its attendant toxicity, particularly cardiovascular toxicity/symptoms.	23778325
Inflammation, Dyslipidemias	Altered Intercellular Communication	Recent research has emphasized the strong association between inflammation and both P-wave dispersion and dyslipidemia.	23778479
Inflammation, Renal Cell Carcinoma	Altered Intercellular Communication	Markers of systemic inflammation predict survival in patients with advanced renal cell cancer.	23778526
Refractory Cytopenia of Childhood, Inflammation	Altered Intercellular Communication	Markers of systemic inflammation contribute significantly to prognostic classification in addition to established factors for pre-treated patients with advanced RCC.	23778526
Autistic behavior, Inflammation	Altered Intercellular Communication	Both ASD groups demonstrated significantly higher 3CT levels than control subjects, suggesting that chronic inflammation was present in both groups of children with ASD.	23778583
Inflammation, Periodontitis	Altered Intercellular Communication	The magnitude of the association between shift work and periodontitis attenuated with adjustment of mediators (smoking and a marker of inflammation).	23780580
Communicable Diseases, Tooth structure, Inflammation	Altered Intercellular Communication	During extraction of the tooth, infection, decay, and inflammation were discovered.	23780593
Gingivitis, Tooth structure, Dental caries	Altered Intercellular Communication	The dental assessment comprised the number of teeth, caries frequency (DMFT index), type and frequency of restorations, quality of oral hygiene (API), degree of gingival inflammation (SBI), probing depths and the presence of recessions.	23780856
Inflammation	Altered Intercellular Communication	Faecal calprotectin and a1-antitrypsin concentrations may be associated with mucosal permeability and inflammation.	23782263
Inflammation, Complication Aspects, Metabolic Syndrome X, ETV3 wt Allele, Non-alcoholic Fatty Liver Disease, Obesity, Overweight	Altered Intercellular Communication	Iron (Fe) sequestration is described in overweight and in its associated metabolic complications, i.e., metabolic syndrome (MetS) and non-alcoholic liver fatty disease (NAFLD); however, the interactions between Fe, obesity and inflammation make it difficult to recognize the specific role of each of them in the risk of obesity-induced metabolic diseases.	23783556
Primary malignant neoplasm	Altered Intercellular Communication	Recent studies have shown that the modified Glasgow Prognostic Score (mGPS), which is an inflammation-based prognostic score, is useful as a prognostic index for some cancer cases.	23784105
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The transcriptome changes in 3-month-old DMD pigs were in good concordance with gene expression profiles in human DMD, reflecting the processes of degeneration, regeneration, inflammation, fibrosis and impaired metabolic activity.	23784375
Necrotizing granulomatous inflammation, Pancreatitis, Malignant Neoplasms, Sarcoidosis	Altered Intercellular Communication	Histology showed changes of chronic pancreatitis and peripancreatic granulomatous inflammation with no evidence of malignancy and a diagnosis of sarcoidosis was made.	23784760
Neoplasms, Traumatic, Aneurysm, Posterior Communicating Artery, Hernia	Altered Intercellular Communication	They are ischaemic microangiopathy, posterior communicating artery aneurysm, uncal herniation, neoplasia, traumatic and inflammatory conditions.	23784767
Malignant - descriptor, Lymphoma, T-Cell, Cutaneous, Dermatitis	Altered Intercellular Communication	In leukemic cutaneous T-cell lymphoma (L-CTCL), malignant T cells accumulate in the blood and give rise to widespread skin inflammation.	23785046
Airway structure, Weight decreased	Altered Intercellular Communication	Systemic and airway inflammation did not change following weight loss.	23786284
Inflammation, Hypertension, CTCAE, IL13 gene, Disease	Altered Intercellular Communication	Whether the inflammation caused by allergic diseases such as allergic rhinitis can predispose to hypertension is controversial.	23786432
Inflammation	Altered Intercellular Communication	Hair characteristics and scalp inflammation were assessed by an interviewer-administered questionnaire.	23786579
Inflammation, Lipohypertrophy, CTCAE	Altered Intercellular Communication	Central lipohypertrophy was not associated with change in scalp hair texture or scalp inflammation in this cohort.	23786579
Inflammation, Thrombosis	Altered Intercellular Communication	Activated platelets play a role in atherogenesis, inflammation and atherothrombosis.	23786593
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Cyclooxygenase-2 (COX-2) is overexpressed during airway inflammation in chronic obstructive pulmonary disease (COPD) patients.	23786928
Multiple Organ Failure, Inflammation, SLC25A10 gene	Altered Intercellular Communication	The JAAM DIC patients were more seriously ill and exhibited more severe systemic inflammation, a higher prevalence of multiple organ dysfunction syndrome (MODS) and worse outcomes than the non-DIC patients.	23787004
Multiple Organ Failure, Inflammation	Altered Intercellular Communication	Disease severity, systemic inflammation, MODS and the mortality rate worsened in accordance with an increased JAAM DIC score on day 1.	23787004
Inflammation, Primary malignant neoplasm, Anemia, Toxic effect	Altered Intercellular Communication	Anemia, a frequent and deleterious condition in patients with cancer, is mainly caused by chemotherapy toxicity, iron deficiency, or inflammation.	23787470
Airway structure, airway disease	Altered Intercellular Communication	Sputum differential count is a useful tool to evaluate airway inflammation in chronic airway diseases.	23787521
Inflammation	Altered Intercellular Communication	Angiogenesis may be induced by intramyocardial injection of autologous bone marrow stem cells, intensified by inflammation around channels performed by laser.	23788089
Inflammation, Toxic effect, Hypotension, CTCAE, Syncope (amphibian), Abdominal Pain, Fatigue	Altered Intercellular Communication	Five patients experienced grade 3 non-haematological toxicity, including symptoms of urothelial inflammation, hypotension and syncope, fatigue and abdominal pain.	23789936
Cholecystitis, Cholestasis	Altered Intercellular Communication	We are reporting a rare case of obstructive cholestasis and cholecystitis due to CMV-related inflammation of the major duodenal papilla in a 60-year-old woman 3 months after renal transplantation.	23790000
Airway structure, Asthma	Altered Intercellular Communication	Persistent airway inflammation, detected by fractional exhaled nitric oxide (FENO), is occasionally observed in asthmatic patients, even in those treated with inhaled corticosteroids (ICS).	23790736
Inflammation, Hemorrhage, Meckel Diverticulum, Perforation (observation), Intestinal Obstruction	Altered Intercellular Communication	Meckel's diverticulum may give rise to bleeding, intestinal obstruction and inflammation; however, its perforation by a foreign body is an extremely rare life-threatening complication.	23790794
Chronic inflammation, Transitional epithelial cell of urinary bladder, Nephrogenic metaplasia	Altered Intercellular Communication	Nephrogenic adenoma is an uncommon urothelial lesion that has been associated with chronic inflammation and surgical manipulation of the urinary tract.	23791211
Inflammation, Comorbidity	Altered Intercellular Communication	Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort.	23791463
ARCN1 gene, Inflammation	Altered Intercellular Communication	Comorbidities, are common in COPD, have been associated with poor outcomes and are thought to relate to systemic inflammation.	23791463
Heart Diseases, Inflammation, Hypertension, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	The comorbidities of heart disease, hypertension and diabetes are associated with increased systemic inflammation.	23791463
Airway structure, Thickened, Eosinophilic inflammation	Altered Intercellular Communication	Periostin, an extracellular matrix protein, contributes to subepithelial thickening in asthmatic airways, and its serum levels reflect airway eosinophilic inflammation.	23791506
Inflammation, Obesity	Altered Intercellular Communication	The relationship between obesity, physical fitness, and inflammation was analyzed in a Polish population aged 12 to 18 years.	23792582
IgG4-Related Sclerosing Disease	Altered Intercellular Communication	IgG4-related disease (IgG4-RD) is a recently described inflammatory condition known to cause tumefactive lesions at myriad anatomical locations.	23793110
Inflammation	Altered Intercellular Communication	A higher degree of systemic inflammation, reflected by the ESR and CRP level, was associated with a smaller proportion of patients consuming alcohol.	23793744
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	These findings suggest the importance of inflammation and angiogenesis in the etiology of colorectal cancer and that genetic and lifestyle factors may be targets for modulating disease risk.	23794399
Airway structure	Altered Intercellular Communication	Increased induced sputum levels of NGAL might be a characteristic feature of overlap, suggesting enhanced neutrophilic airway inflammation and/or airway epithelial injury in COPD-asthma overlap.	23794464
Airway structure, Pneumonitis	Altered Intercellular Communication	Rosiglitazone and pioglitazone attenuated airway neutrophilia in a corticosteroid-resistant mouse model of pulmonary inflammation.	23794466
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	When compared with healthy controls, serum hyaluronan was significantly greater in patients with CIP and was positively correlated with serum biomarkers of inflammation and fibrosis, such as C-reactive protein and surfactant protein-D.	23795990
Hepatitis B, Acute and chronic inflammation, Liver Cirrhosis	Altered Intercellular Communication	Hepatitis B virus (HBV)-related cirrhosis is known to be associated with chronic hepatic inflammation.	23796976
Autoimmune Pancreatitis, Cardiomyopathies, Autoimmune reaction	Altered Intercellular Communication	[Peripartum cardiomyopathy, acute autoimmune pancreatitis and periadipose tissue inflammation - autoimmune reaction?].	23797439
Pancreatitis, Acute, Inflammation, Organ dysfunction syndrome, Cardiomyopathies	Altered Intercellular Communication	A case of 26 year-old female with peripartum cardiomyopathy, acute pancreatitis, periadipose tissue inflammation due to unknown cause and multiple organ dysfunction syndrome complication is presented.	23797439
Inflammation, Colorectal Carcinoma, Ulcerative Colitis	Altered Intercellular Communication	Earlier studies suggest that the severity of inflammation is an independent risk factor for CRC in ulcerative colitis (UC).	23797639
Inflammatory Bowel Diseases, Inflammation, Dysplasia, Colorectal Intraepithelial Neoplasia, Colorectal Carcinoma	Altered Intercellular Communication	We investigated the role of histological inflammation as a risk factor for colorectal dysplasia or CRC to better target dysplasia surveillance in IBD.	23797639
Inflammation, Dysplasia, Colorectal Carcinoma	Altered Intercellular Communication	Histological severe inflammation was present in 41.4% of patients with dysplasia and in 24.1% of patients with CRC, but in only 4.3% of controls.	23797639
Inflammation, Dysplasia, Carcinoma	Altered Intercellular Communication	Severe inflammation had an odds ratio (OR) of 31.8 [95% confidence interval (CI): 15.6-64.9] for dysplasia or carcinoma compared to patients with no inflammation.	23797639
Inflammation, Dysplasia, Colorectal Carcinoma	Altered Intercellular Communication	As conclusion, degree of inflammation and duration of disease cumulatively increase the risk for dysplasia and CRC.	23797639
Autoimmune Diseases, Idiopathic Inflammatory Myopathies, Myositis	Altered Intercellular Communication	Idiopathic inflammatory myopathies (IIM) are a rare group of autoimmune diseases characterized by muscle inflammation.	23797759
Airway structure, Asthma, Bronchial Hyperreactivity	Altered Intercellular Communication	Airway inflammation and bronchial hyperreactivity in steroid naive children with intermittent and mild persistent asthma.	23798479
Airway structure	Altered Intercellular Communication	To our knowledge, there is no study comparing airway inflammation between intermittent and mild persistent asthmatic children.	23798479
Airway structure	Altered Intercellular Communication	Eosinophilic airway inflammation and direct BHR may not be significantly different in intermittent asthmatic children from their peers with mild persistent disease.	23798479
Inflammation, Cell Death	Altered Intercellular Communication	In conclusion, mass spectrometric investigation of exudates from chronic wounds demonstrated dramatic impairment in wound repair with excessive inflammation, antiangiogenic environment, and accelerated cell death.	23798543
Arterial Stiffness, Left Ventricular Hypertrophy, Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Serum 25-hydroxyvitamin D level is associated with arterial stiffness, left ventricle hypertrophy, and inflammation in newly diagnosed hypertension.	23799341
Myocardial fibrosis, vascular inflammations, vascular smooth muscle cell proliferation	Altered Intercellular Communication	Vitamin D may modulate vascular inflammation, vascular smooth muscle cell proliferation, the renin-angiotensin system, and cardiomyocyte proliferation, myocardial fibrosis, and proliferation.	23799341
Arterial Stiffness, Left Ventricular Hypertrophy, Inflammation	Altered Intercellular Communication	Serum 25-hyroxyvitamin D is independently related with arterial stiffness, LVH, and inflammation.	23799341
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Comparison of the prognostic value of longitudinal measurements of systemic inflammation in patients undergoing curative resection of colorectal cancer.	23799846
Colorectal Carcinoma, Malignant Neoplasms	Altered Intercellular Communication	The systemic inflammation-based prognostic scores, modified Glasgow Prognostic Score (mGPS) and the neutrophil-lymphocyte ratio (NLR) are now recognised to be useful in predicting survival in a variety of solid organ malignancies, including colorectal cancer (CRC) before treatment.	23799846
Inflammation, Tooth structure	Altered Intercellular Communication	The tooth was mobile but with minimal inflammation.	23801078
Inflammation, Lymphoproliferative Disorders, Anemia, Angiolymphoid hyperplasia, Thrombocytosis	Altered Intercellular Communication	Multicentric Castleman's disease (MCD) is a polyclonal lymphoproliferative disorder that manifests as marked hyper-g-globulinemia, severe inflammation, anemia, and thrombocytosis.	23801138
Inflammation, Fever, CTCAE, Aplastic Anemia, Anasarca	Altered Intercellular Communication	Case 2: A 73-year-old man with a history of aplastic anemia and remission presented with fever, severe inflammation, and anasarca.	23801138
Inflammation, Atherosclerosis	Altered Intercellular Communication	C-reactive protein (CRP) is a marker of inflammation, which promotes atherosclerosis.	23801460
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Although researchers have consistently demonstrated systemic inflammation in chronic obstructive pulmonary disease (COPD), its origin is yet unknown.	23801879
Pain Distress Question, Psoriasis, Refractory anemias, Rheumatoid Arthritis, Pruritus	Altered Intercellular Communication	Symptoms of itch and pain in chronic inflammatory conditions of psoriasis (PS) and rheumatoid arthritis (RA) can highly affect patients' quality of life.	23802713
Pain Distress Question, Pruritus	Altered Intercellular Communication	This study directly compared whether patients with chronic inflammatory conditions associated with chronic itch or pain display a heightened sensitivity to itch and pain, respectively.	23802713
Refractory anemias, Pain Distress Question, Pruritus	Altered Intercellular Communication	In line with previous studies in other patient groups with chronic itch or pain, further support was found that somatosensory stimuli are processed in line with the patients' main symptom through generic sensitization processes, also in chronic inflammatory conditions such as PS and RA.	23802713
Inflammation, Prostatic Diseases, Prostate carcinoma, Benign prostatic hypertrophy, Structure of posterior cerebral artery	Altered Intercellular Communication	The role of inflammation in prostate diseases is suggested by the presence of inflammatory cells within the prostate in benign prostatic hyperplasia (BPH) and prostate cancer (PCa) patients.	23803120
Inflammation, Prostate	Altered Intercellular Communication	In addition, bacterial and viral infection may lead to chronic and recurrent inflammation of the prostate.	23803120
Human papilloma virus infection, Inflammation, Prostatic Diseases, Prostate carcinoma	Altered Intercellular Communication	Our data do not support a significant role of HPV infection in prostatic disease in Iranian patients, but demographic data indicated a probable association between presence of HPV DNA and risk of inflammation in prostate tissue which might lead to prostate carcinoma.	23803120
Inflammation, Cyst of vagina	Altered Intercellular Communication	Postpartum vaginal cystic lesions constitute a common situation that is caused either by inflammation or by accumulation of lymph.	23803247
Inflammation, Fibrosis Assessment, Fatty Liver Disease	Altered Intercellular Communication	Serum L-FABP levels are elevated in NASH and this elevation is positively correlated with the degree of fibrosis and inflammation.	23803374
Inflammation, Fibrosis Assessment, Fatty Liver Disease	Altered Intercellular Communication	L-FABP levels may aid as a non-invasive marker in determining the severity of fibrosis and inflammation in patients with NASH.	23803374
Inflammation, RTEL1 gene, Obesity	Altered Intercellular Communication	Obesity is associated with inflammation, a cytokine milieu conducive to lymphocyte proliferation, and has been associated with NHL risk in some epidemiologic studies.	23803416
Vitreous inflammatory cells	Altered Intercellular Communication	B-scan ultrasonography showed multiple clumplike echoes suggestive of vitreous inflammation.	23803484
Inflammation, Blood coagulation, Autonomic nervous system disorders	Altered Intercellular Communication	In conclusion, indoor air pollution is associated with inflammation, oxidative stress, blood coagulation and autonomic dysfunction.	23803502
Inflammation, Colorectal Neoplasms, Hereditary	Altered Intercellular Communication	Inherited variation in genes that regulate innate immunity and inflammation may contribute to colorectal neoplasia risk.	23803696
Colorectal Neoplasms	Altered Intercellular Communication	Although the results need to be replicated, our findings suggest that genetic variation in inflammation-related genes may be related to the risk of colorectal neoplasia.	23803696
Inflammation, Obesity, Abdominal	Altered Intercellular Communication	This dysfunction was best predicted by abdominal obesity, inflammation, glucose-intolerance, and systolic dyssynchrony.	23804526
Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Resistin is associated with local and systemic inflammatory conditions with a direct correlation with type 2 diabetes mellitus (T2DM).	23805816
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Correlations of ADMA serum levels with disease activity, systemic inflammation and metabolic syndrome were assessed.	23806325
Airway structure, Asthma	Altered Intercellular Communication	The majority of patients with severe adult-onset asthma are nonatopic and have persistent eosinophilic airway inflammation.	23806634
Inflammation, Metabolic Diseases, Schizophrenia	Altered Intercellular Communication	Inflammation can be a process significant to the development of schizophrenia and metabolic disorders that are frequently found in patients suffering from schizophrenia.	23806968
Eye pain, Inflammatory abnormality of the eye, Corneal edema	Altered Intercellular Communication	Ocular pain and visual acuity improved and corneal edema and ocular inflammation decreased after the surgery.	23807009
Inflammation, hepcidin	Altered Intercellular Communication	The synthesis of hepcidin is upregulated by high iron stores and inflammation.	23807042
Inflammation, hepcidin	Altered Intercellular Communication	It seems that the influence of inflammation on hepcidin levels in haemodialysed patients is not crucial and other factors (e.g.	23807042
Fibrous, Inflammatory Hepatocellular Adenoma, Inflammation, Focal Nodular Hyperplasia	Altered Intercellular Communication	Inflammatory hepatocellular adenoma can show overlapping histological features with focal nodular hyperplasia, including inflammation, fibrous stroma, and ductular reaction.	23807780
Inflammation	Altered Intercellular Communication	The Inflammatory Nutritional Index significantly varied in relation to nutritional status independent of the systemic inflammation (p=0.02).	23808449
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammatory Nutritional Index can be an adjuvant way for biochemical nutritional assessment and follow up in cancer patients with systemic inflammation.	23808449
Inflammation, Hepatitis	Altered Intercellular Communication	iNKT dominating rodent liver are implicated in inflammation, including in hepatitis models.	23808994
Inflammation, Edema	Altered Intercellular Communication	There was no imaging evidence of oedema or inflammation.	23809264
Inflammation, Edema	Altered Intercellular Communication	Imaging does not demonstrate inflammation or oedema in relation to these lesions.	23809264
Myocarditis	Altered Intercellular Communication	Because, myocardial-FDG uptake occurs with diverse physiology, it should be suppressed during evaluation of myocardial inflammation by FDG-PET/CT.	23810066
Heart Diseases, Coronary Arteriosclerosis	Altered Intercellular Communication	Cortisol, a key stress hormone, is associated with coronary atherosclerosis and may accentuate structural and functional cardiac disease.	23810896
Inflammation, Phlebitis, CCR8 protein, human	Altered Intercellular Communication	CCL1-CCR8 interaction may play a critical role in lymphocytic recruitment in IgG4-SC/AIP, leading to duct-centred inflammation and obliterative phlebitis.	23811304
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The influence of Toll like receptor 4 (TLR-4) gene polymorphisms on IL-17 production has also been revealed in UC patients and tissue inflammation in mice.	23811547
Inflammation, Demyelination	Altered Intercellular Communication	Open biopsy revealed inflammation and demyelination, but no malignant cells were detected.	23812076
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Thus, HPA axis hyperactivity in MS coincides with low inflammation and/or high neurodegeneration, and may impact on lesion pathology and molecular mechanisms in NAWM and thereby be of great importance for suppression of disease activity.	23812288
Acute Coronary Syndrome	Altered Intercellular Communication	Inflammation impairs eNOS activation by HDL in patients with acute coronary syndrome.	23812298
Carcinogenic Chlorinated Hydrocarbon	Altered Intercellular Communication	Our data indicated that the higher frequency of inhibitory NK cells combined with fewer activated NK cells may be associated with HCV-related chronic inflammation involved in CHC pathogenesis.	23813131
Inflammation, Cardiovascular morbidity	Altered Intercellular Communication	Persistent inflammation and oxidative stress play a pathogenic role in the high cardiovascular morbidity and mortality of hemodialysis patients.	23813560
Inflammation	Altered Intercellular Communication	Systemic inflammation as assessed by CRP has been associated with averse events after DES implantation.	23813627
Inflammation, Adult Non-Hodgkin Lymphoma	Altered Intercellular Communication	A prospective study of 67 serum immune and inflammation markers and risk of non-Hodgkin lymphoma.	23814017
Inflammation, Ulcer	Altered Intercellular Communication	Biopsy from the esophageal ulcers revealed dense inflammation infiltrated with lymphocytes and macrophages with clusters of strongly positive intracellular fungal spores with a clear area or "halo-like" zone suggestive of Histoplasma capsulatum invasion.	23816727
Infarction, Inflammation, Exophthalmos	Altered Intercellular Communication	Magnetic resonance imaging of the head and sinuses showed inflammation and mass in the ethmoid sinus and nose with partial septal destruction, proptosis, global destruction of the left eye, brain infarction and carotid artery obliteration.	23816728
Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	A study of inflammation-based predictors of tumor response to neoadjuvant chemoradiotherapy for locally advanced rectal cancer.	23816828
Acute Lung Injury, Inflammation, Endothelium	Altered Intercellular Communication	One-lung ventilation during esophagectomy is associated with inflammation, alveolar epithelial and systemic endothelial injury, and the development of acute lung injury (ALI).	23817506
Inflammation, Endothelium	Altered Intercellular Communication	In this proof of concept study, pretreatment with simvastatin in esophagectomy decreased biomarkers of inflammation as well as pulmonary epithelial and systemic endothelial injury.	23817506
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Whether guideline-oriented pharmacotherapy prevents the decline in pulmonary function or reduces systemic inflammation associated with chronic obstructive pulmonary disease (COPD) is uncertain.	23817861
ARCN1 gene, Inflammation, Alveolar	Altered Intercellular Communication	Guideline-oriented pharmacotherapy of COPD improves airflow limitation but does not prevent the alveolar destruction and systemic inflammation under real-world conditions in Taiwan.	23817861
Refractory anemias, Inflammation, physiopathological	Altered Intercellular Communication	Maintaining normal serum vitamin D levels may protect against IL-17-mediated inflammation and vascular dysfunction in RA.	23818717
Inflammation, Critical Illness	Altered Intercellular Communication	Critically ill patients experience severe stress, inflammation and clinical conditions which may increase the utilization and metabolic turnover of vitamin B-6 and may further increase their oxidative stress and compromise their antioxidant capacity.	23819116
Inflammation, Venous Thrombosis, Necrosis	Altered Intercellular Communication	Early complications were not observed, while late ones concerned 16.86% of patients and included: generalized bacteriemia (8.43%), local inflammation of the skin and of the subcutaneous tissue (1.2%), venous thrombosis (2.41%), migration of the catheter (1.2%), necrosis of the skin over the port's chamber (2.41%).	23819398
Neurodegeneration due to 3-hydroxyisobutyryl coenzyme A hydrolase deficiency, Arthritis	Altered Intercellular Communication	A global metabolic profile is identified from all arthritic patients, suggesting that there are common metabolic defects resulting from joint inflammation and lesion.	23819623
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Chronic inflammation was found to be correlated with coronary (CAC) and thoracic peri-aortic calcification (TAC) in end-stage renal disease (ESRD) patients.	23819627
Heart Diseases, Inflammation	Altered Intercellular Communication	Neutrophil-to-lymphocyte ratio (NLR) was introduced as a potential marker to determine inflammation in cardiac and noncardiac disorders.	23819627
Inflammation, Impaired lung function, Symptoms, Chronic Obstructive Airway Disease, Chronic disease, Disability	Altered Intercellular Communication	High rates of disability associated with chronic airway obstruction may be caused by impaired pulmonary function, pulmonary symptoms, other chronic diseases, or systemic inflammation.	23819728
Inflammation, Rupture, Atherosclerosis	Altered Intercellular Communication	Matrix metalloproteinase-9 (MMP-9) plays an important role in inflammation and matrix degradation involved in atherosclerosis and plaque rupture.	23819814
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation has a critical role in the pathogenesis and progression of cancer.	23820252
Inflammation, Muscle damage	Altered Intercellular Communication	While inflammation causes muscle damage in the early phase, metabolic alterations such as an impairment of oxidative metabolism seem to be responsible for the disability in the chronic phase of the disease.	23820876
Inflammation	Altered Intercellular Communication	Inflammation may be a common underlying cause or represents a final common pathway.	23821322
Inflammation, Retinitis Pigmentosa, Uveitis	Altered Intercellular Communication	Clinicians should be aware of various manifestations of RP, including mild inflammation, to avoid possible confusin with uveitis.	23822599
Inflammation, Fibrosis Assessment, Neoplasms, Vascular Tissue, Necrosis	Altered Intercellular Communication	However, final histology demonstrated fibroadipose tissue with fat necrosis and fibrosis, thickened vascular vessels, and diffuse chronic inflammation with lymphocytic infiltrates, which are more consistent with an atypical inflammatory vascular tumor.	23823059
Retinitis, diabetic	Altered Intercellular Communication	Recent findings have implicated the involvement of interferon-g (IFN-g), a part of the Th1 cytokine response, in the retinal inflammation of diabetic patients.	23823918
Hyperglycemia, Inflammation	Altered Intercellular Communication	It is possible that IFN-g production via IL-18 in the retinas of 60-week-old OLETF rats is caused by hyperglycemia, and plays a role in the inflammation of the OLETF rat retinas.	23823918
Inflammation, polyps	Altered Intercellular Communication	The histopathology showed benign polyp with non-specific inflammation.	23823964
Inflammation, Juxtapapillary focal retinitis AND retinochoroiditis	Altered Intercellular Communication	Bilateral anterior chamber inflammation was associated with neuroretinitis in the right eye.	23824660
Autoimmune Diseases, Inflammation, Primary malignant neoplasm, Malignant neoplasm of vulva	Altered Intercellular Communication	The toll-like receptor and the nuclear factor kB (NF-kB) signaling pathways have been implicated in inflammation, autoimmune disease and cancer, but whether common nucleotide variation in these pathways is associated with the risk of cervical and vulvar cancers has received little study.	23824834
Inflammation, Primary malignant neoplasm, Psychiatric, Depression, CTCAE, Psychological Distress	Altered Intercellular Communication	Studies of the biopsychosocial approach covering the psychological implications of cancer (e.g., prevalence of emotional distress, application of DSM/ICD classical, and more recent psychiatric classification systems), their psychobiological concomitants (e.g., inflammation and immune dysregulation mechanisms in depression and chronobiology of stress and cancer), and interpersonal issues (e.g., doctor-patient communication and role of neuron mirror system) are discussed.	23825038
Hypothalamic structure	Altered Intercellular Communication	MAP2K3 is associated with body mass index in American Indians and Caucasians and may mediate hypothalamic inflammation.	23825110
Obesity, Hypothalamic structure	Altered Intercellular Communication	We conclude that MAP2K3 is a reproducible obesity locus that may affect body weight via complex mechanisms involving appetite regulation and hypothalamic inflammation.	23825110
Inflammation, Primary malignant neoplasm, Cardiovascular Diseases	Altered Intercellular Communication	High blood concentrations of n-6 fatty acids (FAs) relative to n-3 FAs may lead to a "physiological switch" towards permanent low-grade inflammation, potentially influencing the onset of cardiovascular and inflammatory diseases, as well as cancer.	23825649
Lung hyperinflation, Inflammation	Altered Intercellular Communication	A significant correlation between E/A ratio and PaO2 was observed (r=0.26, p<0.05), but not with static lung hyperinflation, inflammation or right ventricle overload parameters.	23826360
Nonalcoholic Steatohepatitis, Inflammation, Diabetes Mellitus, Obesity, Liver Cirrhosis	Altered Intercellular Communication	Non-alcoholic steato-hepatitis is more common in the presence of diabetes, obesity, older age and increased inflammation, and is more likely to progress to cirrhosis.	23826593
Inflammation, Pyoderma	Altered Intercellular Communication	Total Count, ESR and CRP are not specific as they can also be elevated in non pyogenic causes of inflammation.	23826894
Bronchitis	Altered Intercellular Communication	Bronchial anthracofibrosis is a rare disease characterised by chronic bronchial inflammation, with bronchoscopic findings showing dark anthracotic pigmentation on the bronchial mucosa in conjunction with bronchial narrowing or obliteration which causes stenosis of the airways.	23827039
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Th17 cells representing novel subset of CD4(+) cells have well described roles in autoimmune diseases and inflammation.	23827655
Communicable Diseases, Inflammation, Neoplasms	Altered Intercellular Communication	It is important to closely monitor a G-CSF producing tumor, when a patient shows severe inflammation, but no infection.	23827867
Inflammation, Osteoarthritis, Knee	Altered Intercellular Communication	Connective tissue growth factor promotes interleukin-1b-mediated synovial inflammation in knee osteoarthritis.	23827951
Inflammation	Altered Intercellular Communication	VEGF predicts all-cause mortality, independent of inflammation, while an elevated sVEGFR-1 level increased the mortality risk in inflamed patients.	23828162
Inflammation, Renal function, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD) is characterized by a continuous reduction in kidney function, increased inflammation, and reduced antioxidant capacity.	23828329
Inflammation	Altered Intercellular Communication	Baseline data demonstrated elevated inflammation and low antioxidant levels.	23828329
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	This study demonstrates that mild and moderate CKD is associated with chronic inflammation and low antioxidant activity.	23828329
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Systemic inflammation and impaired antioxidant status may be greater in CKD populations with multiple comorbidities.	23828329
Ischemia, Inflammation, Perforation (observation), Small bowel obstruction, Adenocarcinoma of large intestine	Altered Intercellular Communication	To this end, 56 patients were assigned to the following groups according to their disease: bowel ischaemia (group 1: n = 14), small bowel obstruction (group 2: n = 12), acute inflammation (group 3: n = 6), perforation (group 4: n = 8), and colorectal adenocarcinoma (group 5: n = 16).	23828592
Cancer-related fatigue, Chronic inflammation	Altered Intercellular Communication	Muscular fitness, cardiorespiratory fitness (CRF) and fatness are mutually related with chronic inflammation.	23828843
Inflammation	Altered Intercellular Communication	Adolescents with higher levels of muscular fitness present a lower chronic inflammation, and this seems to be explained by lower levels of fatness.	23828843
Inflammation	Altered Intercellular Communication	Any concentration of secretory leukocyte protease inhibitor (SLPI) indicates the dominant hyperergic inflammation in periodontal tissues, accompanied by increased proteolysis.	23828974
Inflammation, Hemolysis (biological function)	Altered Intercellular Communication	Acute hemolysis after intravenous immunoglobulin amid host factors of ABO-mismatched bone marrow transplantation, inflammation, and activated mononuclear phagocytes.	23829192
Inflammation, Hemolysis (lab result)	Altered Intercellular Communication	Synergizing host factors (including obesity-unadjusted dosing and existing inflammation) marked this severe post-IVIG hemolytic crisis.	23829192
Inflammation	Altered Intercellular Communication	Multi-factorial causes of CSA-AKI involve oxidative stress and inflammation.	23829828
Inflammation, Cerebral Ischemia	Altered Intercellular Communication	Evidence in human and animal models shows BBB disruption is associated with activation of matrix metalloproteinase-9 (MMP-9) after cerebral ischemia and inflammation.	23829879
Inflammation	Altered Intercellular Communication	Adipocyte fatty acid-binding protein (A-FABP) plays a key role in obesity-related insulin resistance and inflammation which may be involved in the pathogenesis of sarcopenic obesity (SO).	23830287
Diabetic Neuropathies	Altered Intercellular Communication	Our study indicates that Munc13-1, on account of its role in both insulin and neurotransmitter exocytosis and through its binding properties, may be an important factor contributing to the development or progression of diabetic neuropathy.	23830992
Infection	Altered Intercellular Communication	Premature aging can impair lung function by different ways: by interfering specifically with tissue repair mechanisms after damage, thus perturbing the correct crosstalk between mesenchymal and epithelial components; by inducing systemic and/or local alteration of the immune system, thus impairing the complex mechanisms of lung defense against infections; and by stimulating a local and/or systemic inflammatory condition (inflammaging).	23831269
Infection	Altered Intercellular Communication	Premature aging can impair lung function by different ways: by interfering specifically with tissue repair mechanisms after damage, thus perturbing the correct crosstalk between mesenchymal and epithelial components; by inducing systemic and/or local alteration of the immune system, thus impairing the complex mechanisms of lung defense against infections; and by stimulating a local and/or systemic inflammatory condition (inflammaging).	23831269
Inflammation, Dental Plaque, physiopathological	Altered Intercellular Communication	Arginase-II (Arg-II) has been shown to promote vascular dysfunction and plaque vulnerability phenotypes in mice through uncoupling of endothelial nitric oxide synthase and activation of macrophage inflammation.	23832324
Oophoritis	Altered Intercellular Communication	Xanthomatous oophoritis is a rare inflammatory condition of the ovaries.	23833001
Airway structure, Airway Obstruction	Altered Intercellular Communication	Both are characterized by heterogeneous chronic airway inflammation and airway obstruction.	23833163
Inflammation, Calcinosis	Altered Intercellular Communication	Focal arterial inflammation precedes subsequent calcification in the same location: a longitudinal FDG-PET/CT study.	23833282
vascular inflammations	Altered Intercellular Communication	We sought to test the hypothesis that local vascular inflammation predisposes to subsequent arterial calcium deposition in humans.	23833282
Inflammation, Dental Plaque	Altered Intercellular Communication	Here, we provide first-in-man evidence that arterial inflammation precedes subsequent Ca deposition, a marker of plaque progression, within the underlying location in the artery wall.	23833282
Airway structure, Exacerbation	Altered Intercellular Communication	COPD exacerbations are associated with neutrophilic airway inflammation.	23834268
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	Relationships of different blood pressure categories to indices of inflammation and platelet activity in sustained hypertensive patients with uncontrolled office blood pressure.	23834704
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	In conclusion, in hypertensive patients with uncontrolled office BP, presence of non-dipping BP is associated with increased platelet activity and inflammation, which can be one of the underlying plausible mechanisms of non-dipping BP status.	23834704
Inflammation, Lower respiratory tract infection, Respiratory Tract Infections, Acute onset cough	Altered Intercellular Communication	Point-of-care C-reactive protein (POCCRP) is a biomarker of inflammation that offers clinicians a rapid POC test to guide antibiotic prescribing decisions for acute cough and lower respiratory tract infections (LRTI).	23834883
Inflammation, Neoplasms	Altered Intercellular Communication	Elevated FAP-a expression may be associated with inflammation and suppressed lymphocyte-dependent immune response, which then result in the tumor progression.	23835897
Coughing, Gastroesophageal reflux disease, Airway structure	Altered Intercellular Communication	We conclude that cough accompanying GERD is unlikely to be associated with the presence of co-morbid asthma, but rather suggests a mild airway inflammation developing as a sequel of GERD.	23835974
Autoimmune Diseases, Granulomatous inflammation, Pulmonary vascular system, Vasculitis, CTCAE	Altered Intercellular Communication	Pulmonary vasculitis is a potentially lethal autoimmune disease characterized by granulomatous inflammation of respiratory tract, necrotizing vasculitis affecting small-to medium-size vessels and antineutrophil cytoplasmic antibodies elevation.	23835997
Specimen Type - Fistula, Pelvic Inflammatory Disease	Altered Intercellular Communication	This simple treatment produced a cure of the pelvic inflammation and closure of the fistula without compromising a more aggressive secondary treatment which was not necessary in our series.	23836114
Inflammation, Schizophrenia	Altered Intercellular Communication	Inflammation and schizophrenia: alterations in cytokine levels and perturbation in antioxidative defense systems.	23836841
Inflammation, Schizophrenia	Altered Intercellular Communication	A relationship between inflammation and schizophrenia has been supported by abnormal cytokine production and altered antioxidant status.	23836841
Inflammation, Schizophrenia	Altered Intercellular Communication	We conclude that inflammation resulting from dysregulation of cytokines and altered antioxidant systems may play a critical role in the etiology of schizophrenia.	23836841
Schizophrenia, Virus Diseases, Abnormal synaptic transmission, Immune System Diseases	Altered Intercellular Communication	Although several theories have been proposed including developmental/neurodegenerative processes, neurotransmitter abnormalities, viral infection, and immune dysfunction, the exact causative factor of schizophrenia is unclear.	23836841
Inflammation	Altered Intercellular Communication	Fragmented cytokeratin-18 (CK-18) levels were positively correlated with NAS (r=0.401), as well as NAS components such as lobular inflammation (r=0.387) and ballooning (r=0.231).	23837136
Inflammation, Endothelial dysfunction, Diabetic Retinopathy	Altered Intercellular Communication	The role of inflammation and endothelial dysfunction in the pathogenesis of diabetic retinopathy.	23837221
Diabetic Retinopathy, Inflammation, Endothelial dysfunction, GDC Disease Response Terminology	Altered Intercellular Communication	The pathogenesis of diabetic retinopathy (DR) is insufficiently understood and presumed to possibly involve inflammation and endothelial dysfunction.	23837221
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The groups did not differ in the levels of inflammation markers, other markers of endothelial dysfunction and anthropometric parameters.	23837221
Inflammation, Obesity, GDC Disease Response Terminology	Altered Intercellular Communication	The study demonstrated that the association between obesity, inflammation and other risk factors plays an important role in endothelial impairment involved in the pathogenesis of DR.	23837221
Inflammation, Liver Stiffness	Altered Intercellular Communication	Multivariate analysis revealed no correlation between the grade of histologic inflammation and liver stiffness measured by magnetic resonance elastography (R2 = 0.265, p = 0.47).	23837611
Inflammation, Depression, CTCAE	Altered Intercellular Communication	These results are consistent with previous findings in this cohort for systemic inflammation, blood pressure, and ST segment depression.	23838152
Inflammation, Gland, Colitis	Altered Intercellular Communication	A surgical biopsy showed chronic colitis with inflammation extending to the muscularis mucosae, with areas of glandular atrophy.	23838945
ARCN1 gene, Inflammation	Altered Intercellular Communication	The MPR, which was independently associated with systemic inflammation and airflow limitation, was impaired in patients with COPD.	23839654
Pain Distress Question, Inflammation	Altered Intercellular Communication	In patients with CP, with opiate-dependent abdominal pain, circulating cytokine levels are low suggesting that pain in this disease is not simply a manifestation of inflammation.	23840145
Cystadenoma, Mucinous, Carcinoid Tumor, Granulomatous inflammation, Adenocarcinoma, Fibrous, Diverticulum, Adult Non-Hodgkin Lymphoma, Adenomatous Polyps	Altered Intercellular Communication	The unusual histopathological findings included fibrous obliteration (n = 62), enterobius vermicularis (n = 31), eosinophilic infiltration (n = 10), mucinous cystadenoma (n = 8), carcinoid tumor (n = 6), granulomatous inflammation (n = 5), adenocarcinoma (n = 4; one of them mucinous), and mucocele (n = 3), adenomatous polyp (n = 1), taenia sup (n = 1), ascaris lumbricoides (n = 1), appendiceal diverticula (n = 1), and B cell non-hodgkin lymphoma (n = 1).	23840147
Communicable Diseases, Neurologic Deficits, Inflammation, Trauma, Nervous System	Altered Intercellular Communication	Shortly after infection, HIV enters the brain and causes widespread inflammation and neuronal damage, which ultimately leads to neuropsychological impairments.	23840428
methyldopa, Inflammation	Altered Intercellular Communication	This paper outlines the importance of association between inflammation and AMD.	23840568
methyldopa, Inflammation	Altered Intercellular Communication	This provides further evidence for the link between A2E, inflammation, and the pathogenesis of AMD.	23840644
ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	In chronic obstructive pulmonary disease (COPD), primarily caused by cigarette smoke (CS), lung inflammation persists and smooth muscle tone remains elevated, despite ample amounts of nitric oxide that could activate sGC.	23841447
Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Neutrophilic dermatosis, Senile purpura	Altered Intercellular Communication	We studied 95 cases diagnosed as solar purpura and identified 10 cases (10.5%) in which significant neutrophilic inflammation was present, potentially simulating a leukocytoclastic vasculitis or neutrophilic dermatosis.	23842046
Inflammation, Damage	Altered Intercellular Communication	The classifier consists of 17 peptides derived from albumin, b2-microglobulin, CD99, fibronectin and various collagen a-chains, indicating inflammation, activation of T cells and changes in the extracellular matrix as early signs of GvHD-induced organ damage.	23842427
Inflammation, Obesity	Altered Intercellular Communication	Chronic inflammation, which is associated with obesity, may play a role in the etiology of several diseases.	23844105
Inflammation	Altered Intercellular Communication	These results suggest that posited anti-inflammatory drugs and behaviors may be less strongly associated with inflammation among the obese than among lower weight persons.	23844105
Data types - Address	Altered Intercellular Communication	Inflammation clearly occurs in pathologically vulnerable regions of the AD brain, with increased expression of acute phase proteins and pro-inflammatory cytokines.	23844688
ARCN1 gene, Inflammation	Altered Intercellular Communication	Because pathogenesis, disease activity and disease progression in COPD are believed to be partly dependent of neutrophil driven inflammation we decided to investigate whether plasma level of calprotectin (p-calprotectin) was associated with all-cause mortality in patients with COPD.	23844942
Hemospermia, Inflammation, Prostate	Altered Intercellular Communication	Hematospermia is usually caused by nonspecific inflammation of the prostate and seminal vesicles.	23845256
Inflammation, Traumatic injury	Altered Intercellular Communication	The initiating factor in internal root resorption is thought to be trauma or chronic pulpal inflammation, but other aetiological factors have also been suggested.	23845670
Inflammation, immunoglobulin A, Epithelial cyst	Altered Intercellular Communication	Histopathological examination showed immunoreactivity to IgA on the luminal surface of the epithelial ductal cyst and mild chronic inflammation in the underlying stroma or lacrimal gland.	23846204
Inflammation	Altered Intercellular Communication	Our results suggest that a multifactorial mechanism leads to dacryops including chronic inflammation, an immune response, and IgA hypersecretion with an osmotic effect, all contributing to the cyst formation.	23846204
Tissue damage, Inflammation	Altered Intercellular Communication	p.R482W-prelamin-A also induced oxidative stress, DNA damages, and inflammation.	23846499
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Lipidosterolic extract of serenoa repens modulates the expression of inflammation related-genes in benign prostatic hyperplasia epithelial and stromal cells.	23846725
Inflammation	Altered Intercellular Communication	These results suggest that LSESr may be useful to treat BPH that manifest inflammation characteristics.	23846725
Inflammation	Altered Intercellular Communication	This also supports a role for inflammation in BPH presumably by mediating the balance between apoptosis and proliferation.	23846725
Inflammation, Dyslipidemias, Lower Urinary Tract Symptoms	Altered Intercellular Communication	Dyslipidemia and chronic inflammation may play a role in the cause of lower urinary tract symptoms (LUTS) in older men.	23847173
Cardiac Hypertrophy, Inflammation	Altered Intercellular Communication	And also to explore the correlation of cardiac hypertrophy and inflammation.	23847952
Inflammation, Anemia, Chronic Kidney Diseases, Diabetes Mellitus	Altered Intercellular Communication	Our results also determined MCV as an independent predictor of composite CV events independent of anaemia, inflammation, diabetes and eGFR in patients with CKD.	23848392
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is present in every stage of the atherosclerosis process, therefore, inflammation hallmarks such as the fibrinogen can be related to the complications in which it intervenes, mortality is one of them.	23849212
Human papilloma virus infection, Sex Behavior, Uterine Cervicitis	Altered Intercellular Communication	HPV infection was associated with age, sexual behavior and chronic inflammation of the cervix and vagina.	23849649
Cataract, Inflammatory abnormality of the eye	Altered Intercellular Communication	To determine whether postoperative ocular inflammation is less after femtosecond laser-assisted cataract surgery than after conventional phacoemulsification (manual) cataract surgery.	23850229
Cataract, Inflammation	Altered Intercellular Communication	Anterior segment inflammation was less after femtosecond laser-assisted cataract surgery than after manual cataract surgery, and this appeared to be due to a reduction in phacoemulsification energy.	23850229
Inflammation	Altered Intercellular Communication	In 50 knees, 90% of capsular sites were involved by inflammation in comparison with 23% of intracapsular sites and 4.7% of extracapsular sites (P < 0.0001).	23850896
Pancreatitis, Acute, Inflammation, Pancreatitis, Cardiovascular Diseases	Altered Intercellular Communication	The low-grade inflammation that characterizes cardiovascular disorders may facilitate the development of pancreatitis; therefore, we investigated the connection between cardiovascular disorders and acute pancreatitis.	23851434
Hyperplasia, Traumatic injury	Altered Intercellular Communication	The etiology and pathogenesis of condylar hyperplasia remain uncertain, but it has been suggested that its etiology may be associated with hormonal factors, trauma, and hereditary hypervascularity, affecting both genders.	23851829
Inflammation	Altered Intercellular Communication	Apoptosis plays a critical role in the regulation of inflammation and host immune response which helps in tissue homeostasis, and a disturbance in this is often associated with disease.	23852253
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	Taken together, decreased 25(OH)D and increased ferritin serum levels indicate the severity of hepatic inflammation and fibrosis in patients infected chronically with HCV type 1.	23852677
muscle fibrosis, Inflammation, Edema	Altered Intercellular Communication	Magnetic resonance imaging (MRI) revealed muscle fibrosis in directly injected muscles, whereas in subcutaneous fat and within muscles of anterior and posterior compartments of both thighs, not directly injected, there were signal changes supportive of oedema and inflammation.	23853507
ARCN1 gene, Inflammation	Altered Intercellular Communication	Chronic inflammation and changes to the lung extracellular matrix (ECM) have been implicated in the pathogenesis of COPD, yet the mechanisms that lead to PH secondary to COPD remain unknown.	23855769
Inflammation, Metabolic Diseases, Depression, CTCAE	Altered Intercellular Communication	There is evidence that depression is accompanied by inflammation, oxidative and nitrosative stress (O&NS) and metabolic disorders.	23856278
Inflammation, Metabolic Diseases, Suicide	Altered Intercellular Communication	This study examines whether a history of suicide attempts is associated with inflammation, O&NS and metabolic disorders.	23856278
Inflammation, Fever	Altered Intercellular Communication	All had signs of local inflammation, three showed locoregional inflammation, three were febrile.	23856550
Communicable Diseases, Inflammation, Lymphadenopathy	Altered Intercellular Communication	In all cases, there was no sign of local inflammation, regional lymphadenopathy or systemic infection at the last follow-up.	23856550
Inflammation, Chagas Disease	Altered Intercellular Communication	While MMP-9 seems to be involved in the inflammation and cardiac remodeling of Chagas disease, MMP-2 does not correlate with inflammatory molecules.	23856618
Inflammation, atherosclerotic	Altered Intercellular Communication	However, inflammation due to overproduction of IL-6 persisted, and atherosclerotic vascular events occurred as critical complications, even though the serum levels of lipids were very low.	23857095
ARCN1 gene, Inflammation, Respiration Disorders, Simultaneous	Altered Intercellular Communication	Monitoring inflammation in the upper airways can be a useful tool for evaluating respiratory diseases in the elderly and in those with concomitant asthma and COPD, a clinical entity not yet fully understood.	23857681
Inflammation, Fracture	Altered Intercellular Communication	Epidemiological studies have shown low-grade inflammation measured by high-sensitivity C-reactive protein (hs-CRP) to be associated with fracture risk in women.	23857741
Inflammation, Impaired cognition	Altered Intercellular Communication	A significant rise in CRP concentrations over 12 months, but lack of significant association with cognition, provide no evidence for a relationship between systemic inflammation and cognitive decline in amnestic MCI.	23857873
Kidney Failure, Chronic, Inflammation, Malnutrition, Cardiac dysfunction	Altered Intercellular Communication	Little is known about the impact of low triiodothyronine (T3) levels on mortality in end-stage renal disease (ESRD) patients starting hemodialysis (HD) and whether this impact is mediated by malnutrition, inflammation, or cardiac dysfunction.	23857979
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	These data suggest that dietary factors involved in inflammation and oxidative stress interact with MAPK-signaling genes to alter risk of colorectal cancer.	23859041
Inflammation, Thrombosis, Pulmonary Embolism, Pneumonia, Pulmonary Emphysema	Altered Intercellular Communication	Of the CT findings on day 5, pneumonia, pulmonary embolism, portal or mesenteric thrombosis, operative area fat infiltration, peritoneal effusion, pneumoperitoneum, intra-abdominal collection, parietal inflammation or collection, and subcutaneous emphysema were observed in both groups without any significant difference.	23860629
Inflammation, hepcidin	Altered Intercellular Communication	Ferroportin in monocytes of hemodialysis patients and its associations with hepcidin, inflammation, markers of iron status and resistance to erythropoietin.	23860963
HD Term Type, Inflammation, hepcidin	Altered Intercellular Communication	Decreased ferroportin in monocytes of HD patients accompanies increased hepcidin, inflammation, decreased iron availability and is correlated with resistance to rHuEpo treatment.	23860963
Inflammation, Edema	Altered Intercellular Communication	Serum amyloid A as a major protein involved in the acute and chronic stages of inflammation, and IL-6 and bFGF were significantly associated with the extent of macular edema in patients with RVO.	23861862
Inflammation	Altered Intercellular Communication	Wine- or magenta-colored colloid and inflammation were found in one or both sides of the seminal vesicle in all the cases.	23862232
Hepatitis B, Hepatitis C, Hepatitis	Altered Intercellular Communication	To investigate the relationship between hepatitis B virus (HBV) genotypes and hepatitis B early antigen (HBeAg) as well as the hepatitis C antibody, alanine aminotransferase (ALT) levels and liver inflammation and damage in chronic patients of hepatitis B.	23862244
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	The degree of hepatic inflammation, fibrosis stage and alanine aminotransferase levels were similar in both the groups (p > 0.05).	23862244
Granuloma, Granulomatosis, Non-necrotizing granulomatous inflammation, Swelling, Vulva	Altered Intercellular Communication	Ano-genital granulomatosis is a rare chronic inflammatory condition and that can present as diffuse penile, scrotal, vulvar or ano-perineal swelling with non-caseating non-necrotising granulomas on histology.	23862402
Inflammation, Atherosclerosis, Cerebrovascular accident	Altered Intercellular Communication	Phosphodiesterase 4D (PDE4D), through the regulation of cyclic AMP, modulates inflammation and other processes that affect atherosclerosis and stroke.	23863764
Inflammation	Altered Intercellular Communication	This PDE4D genotype may lead to accelerated cyclic AMP degradation and subsequently elevated inflammation 1 day after CEA.	23863764
Inflammation, Primary malignant neoplasm, Obesity	Altered Intercellular Communication	Their dysfunctions are associated with aging, cancer, obesity, and inflammation.	23863811
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Several lines of evidence suggest the involvement of NPY in the regulation of rheumatoid arthritis (RA), and VIP has already been identified as a potent anti-inflammatory factor that reduces joint inflammation.	23864142
Inflammation, Necrosis	Altered Intercellular Communication	The muscle histology demonstrated pronounced acute inflammation and limited necrosis of muscle fibers confined to the right gluteal muscles.	23864208
Liver carcinoma, Complete atrioventricular block, Malignant Neoplasms, FAM126A gene, Hepatitis B, Chronic	Altered Intercellular Communication	Hepatocellular carcinoma (HCC) is an inflammation-related malignancy and chronic hepatitis B (CHB) predisposes to HCC.	23864279
Pancreatitis	Altered Intercellular Communication	Acute pancreatitis is well defined as pancreatic inflammation due to the activation of pancreatic enzymes secondary to several etiological factors.	23864450
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The pathology showed moderate chronic inflammation and erosion of the gastric body mucosa, with accompanying Helicobacter pylori infection.	23864452
Inflammation, Amyloidosis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The pathology showed chronic mild-moderate inflammation of the gastric body mucosa associated with interstitial amyloidosis, with accompanying Helicobacter pylori infection.	23864452
Benign Prostatic Hyperplasia, Inflammation, Prostatic Diseases, Prostate carcinoma, Prostate	Altered Intercellular Communication	Close links have been noted between chronic inflammation of the prostate and the development of human prostatic diseases such as benign prostate hyperplasia (BPH) and prostate cancer.	23864729
prostatitis	Altered Intercellular Communication	However, the molecular mechanisms that contribute to prostatic inflammation remain largely unexplored.	23864729
Inflammation, Prostate carcinoma, Prostatic Diseases, Prostatic Infection	Altered Intercellular Communication	Given that human prostatic infections are associated with chronic inflammation, the development of BPH is associated with an accumulation of senescent cells with a proinflammatory phenotype, and the development of prostate cancer is associated with the loss of IFN signaling, the role of AIM2 in mediating the formation of prostatic diseases was investigated.	23864729
Traumatic injury	Altered Intercellular Communication	Inflammation represents the immune system response to external or internal aggressors such as injury or infection in certain tissues.	23864770
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	The body's response to cancer has many parallels with inflammation and repair; the inflammatory cells and cytokines present in tumours are more likely to contribute to tumour growth, progression, and immunosuppression, rather than in building an effective antitumour defence.	23864770
Inflammation, Dysplasia, Malignant Neoplasms, Thrombopoietin Receptor Agonist LGD-4665, Atrophic, HGD gene	Altered Intercellular Communication	Histopathology revealed 10 inflammation, 14 atrophy, 10 metaplasia, 1 low grade dysplasia (LGD), 5 high grade dysplasia (HGD) and 3 cancers.	23864787
Inflammation, Fibrosis Assessment, Transplant glomerulopathy	Altered Intercellular Communication	Compared to no-AR, all histologic types of AR led to abnormal histology in 1 and 2 years protocol biopsies, including more fibrosis + inflammation (6.3% vs. 21.9%), moderate/severe fibrosis (7.7% vs. 13.5%) and transplant glomerulopathy (1.4% vs. 8.3%, all p < 0.0001).	23865852
Inflammation	Altered Intercellular Communication	In DSA negative recipients, early AR often leads to persistent graft inflammation and increases the risk of new DSA II production.	23865852
Inflammation, Gilbert Disease (disorder)	Altered Intercellular Communication	Haem catabolism: a novel modulator of inflammation in Gilbert's syndrome.	23865893
Inflammation, Gilbert Disease (disorder), Noncommunicable Diseases	Altered Intercellular Communication	Furthermore, reduced body mass index in Gilbert's syndrome individuals was linked to reduced inflammation status, which could be influenced by circulating haem oxygenase catabolites and contribute to reduced risk of noncommunicable diseases in this population.	23865893
Inflammation, Meckel Diverticulum, Peutz-Jeghers Syndrome, Disorder of small intestine, Crohn Disease, Henoch-Schoenlein Purpura	Altered Intercellular Communication	Of the 70 children, 58 (83%) had small bowel disease according to the single-balloon enteroscopy results, including 24 cases of non-specific inflammation, 12 cases of allergic purpura, 8 cases of Crohn's disease, 8 cases of Meckel's diverticulum, and 6 cases of Peutz-Jeghers syndrome.	23866276
Cataract, Inflammation, Uveitis	Altered Intercellular Communication	[Clinical research of anterior chamber inflammation after phacoemulsification surgery in patients with complicated cataract secondary to uveitis].	23866701
Inflammation, Uveomeningoencephalitic Syndrome, Behcet Syndrome	Altered Intercellular Communication	To investigate anterior chamber inflammation after phacoemulsification with intraocular lens (IOL) implantation in patients with Vogt-Koyanagi-Harada (VKH) syndrome or Behcet's disease (BD).	23866701
Inflammation, Uveomeningoencephalitic Syndrome	Altered Intercellular Communication	Anterior chamber inflammation reaches peak levels one week postoperatively in VKH and BD patients who receive phacoemulsification with IOL implantation.	23866701
Inflammation, Infectious Lung Disorder, Septic Shock	Altered Intercellular Communication	Pulmonary infection, and not systemic inflammation, accounts for increased concentrations of exhaled nitric oxide in patients with septic shock.	23867579
Inflammation, respiratory, Infectious Lung Disorder	Altered Intercellular Communication	To assess whether a pulmonary infection itself or systemic inflammation is responsible for NO production, we determined exhaled NO in ventilated patients with respiratory and non-respiratory septic shock and compared it with the concentration in ventilated intensive care patients without systemic inflammation.	23867579
Inflammation	Altered Intercellular Communication	The controls without systemic inflammation, as witnessed by the absence of systemic inflammatory response syndrome criteria and low levels of interleukin-6, had similar concentrations of NO as the patients with non-respiratory septic shock.	23867579
Inflammation	Altered Intercellular Communication	This can be a non-inflammatory process, but it may also result from chronic inflammation occurring in the suprachoroidal space.	23867717
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Inflammation plays a critical role in the pathogenesis of obstructive sleep apnea syndrome (OSAS).	23868710
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Within abnormal distal ileal segments, the mean contrast enhancement ratio of acute inflammation was 2.39 +- 0.59 compared with 1.82 +- 0.63 (P < 0.05) in segments with fibrosis only.	23869486
Inflammation, Hypertriglyceridemia, Endothelial dysfunction	Altered Intercellular Communication	Several authors have reported the association of postprandial hypertriglyceridemia with oxidative stress, systemic inflammation and endothelial dysfunction.	23869888
Inflammation, Hypersensitivity	Altered Intercellular Communication	Orbital inflammation secondary to a delayed hypersensitivity reaction to sub-Tenon's hyaluronidase.	23869964
Orbital Pseudotumor, Allergy - Charge Type Reason	Altered Intercellular Communication	We report a rare case of a delayed orbital inflammation with raised intraocular pressure as a result of hyluronidase allergy following sub-Tenon's anaesthesia.	23869964
Allergic, Orbital Pseudotumor	Altered Intercellular Communication	Here, we have shown evidence to prove the orbital inflammation to be an allergic response to hyluronidase with a skin patch test.	23869964
Allergic, Allergy - Charge Type Reason	Altered Intercellular Communication	This case demonstrates hyaluronidase allergy should be considered as a differential diagnosis among patients presenting with acute post-operative orbital inflammation, even if there is a history of previous exposure to hyaluronidase in the fellow eye with no subsequent allergic response.	23869964
Communicable Diseases, Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor alpha (TNF-a) plays an important role in inflammation, immunity, and defense against infection and clearance of human papillomavirus (HPV).	23870134
Acute Lung Injury, Inflammation, Multiple Organ Failure	Altered Intercellular Communication	Heparin-binding protein is released by neutrophils during inflammation and disrupts the integrity of the alveolar and capillary endothelial barrier implicated in the development of acute lung injury and systemic organ failure.	23870614
Alzheimers Disease", Inflammation	Altered Intercellular Communication	Alzheimer's disease treated patients showed different patterns for oxidative stress and inflammation markers.	23871825
Airway structure	Altered Intercellular Communication	Chronic airway inflammation can be mediated by an enhanced neutrophil oxidative burst.	23872721
Inflammation, Colonization	Altered Intercellular Communication	A markedly increased ROS production in sputum neutrophils during bacterial AECOPD shows an inflammatory response reflecting enhanced local inflammation, which can be mediated by bacterial colonization.	23872721
Inflammation, Chronic disease	Altered Intercellular Communication	Handgrip strength (HGS) has been shown to predict survival and is associated with changes in body composition, nutritional status, inflammation, and functional ability in several chronic disease conditions.	23872952
Communicable Diseases, Inflammation	Altered Intercellular Communication	Signs of infection and inflammation mostly resolved within 1 to 2 weeks after the treatment.	23873492
Inflammation, Thrombosis	Altered Intercellular Communication	Because of the critical role of neutrophils in inflammation associated thrombosis, we asked whether neutrophil tissue factor (TF) may be implicated in the thrombotic diathesis in AAV.	23873874
Inflammation, Thrombosis, Tissue Factor	Altered Intercellular Communication	Expression of TF in NETs and neutrophil derived MPs proposes a novel mechanism for the induction of thrombosis and inflammation in active AAV.	23873874
Sample Size Calculation, vascular inflammations	Altered Intercellular Communication	Global chemokine expression in systemic sclerosis (SSc): CCL19 expression correlates with vascular inflammation in SSc skin.	23873879
Sample Size Calculation, vascular inflammations	Altered Intercellular Communication	To characterise global chemokine expression in systemic sclerosis (SSc) skin in order to better understand the relationship between chemokine expression and vascular inflammation in this disease.	23873879
vascular inflammations	Altered Intercellular Communication	We tested correlations between the most regulated chemokines and vascular inflammation and macrophage recruitment.	23873879
vascular inflammations	Altered Intercellular Communication	Expression of CCL19 in dcSSc skin correlated with markers of vascular inflammation and macrophage recruitment.	23873879
Inflammation	Altered Intercellular Communication	Induction of CCL19 in macrophages but not structural cells indicates a role for skin-resident or recruited immune cells in perivascular inflammation.	23873879
Inflammation	Altered Intercellular Communication	This study demonstrates that CCL19 is a sensitive marker for the perivascular inflammation and immune cell recruitment seen in dcSSc skin disease.	23873879
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Pathological evaluation revealed chronic inflammation of the bronchial mucosa, submucosal carbon particle deposition, and mucosal or submucosal fibrosis.	23876887
Orthodontic, Inflammation, Dental Plaque	Altered Intercellular Communication	Plaque control is the major consensus during orthodontic treatment to prevent the occurrence of cavities and periodontal inflammation.	23876953
Granulomatosis with polyangiitis, Glomerulonephritis, Vasculitis, CTCAE	Altered Intercellular Communication	Wegener's granulomatosis or granulomatosis polyangiitis associated (GPA) is a granulomatous inflammation of the upper and lower respiratory tracts associated with necrotising vasculitis of small and medium-sized blood vessels and, frequently, necrotising glomerulonephritis.	23877415
Inflammatory Bowel Diseases, Inflammation, Defecation	Altered Intercellular Communication	Functional bowel symptoms in quiescent inflammatory bowel diseases: role of epithelial barrier disruption and low-grade inflammation.	23878165
Inflammatory Bowel Diseases, Inflammation, Irritable Bowel Syndrome	Altered Intercellular Communication	To determine the role of colonic barrier defects and low-grade inflammation in irritable bowel syndrome (IBS)-like symptoms in quiescent inflammatory bowel disease (IBD).	23878165
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	In quiescent IBD, IBS-like symptoms related to persistent subclinical inflammation associated with increased colonic paracellular permeability.	23878165
Inflammation, Hemorrhage	Altered Intercellular Communication	Thought to represent a reparative response to intrabony haemorrhage and inflammation, CGCG was once regarded as a reactive lesion.	23878288
Inflammation, Hepatitis A, Stomatitis, Cheilitis, Glossitis	Altered Intercellular Communication	Hepatitis A is known to be associated with inflammation of oral mucosa with stomatitis occurring in 78.5% of the patients, glossitis in 71.4%, cheilitis in 64.3%, marginal periodontal inflammation in 85.7%.	23879055
Inflammation	Altered Intercellular Communication	Genetic polymorphisms related to inflammation and lipid metabolism warrant further investigation for their associations with DKD.	23879411
Increased insulin level, Inflammation, Hyperglycemia, Diabetes Mellitus	Altered Intercellular Communication	The mechanisms through which diabetes is assumed to promote oncogenesis include insulin resistance and associated hyperinsulinemia, hyperglycemia, and inflammation.	23879470
Inflammation	Altered Intercellular Communication	The relative contribution of the local vs. peripheral inflammation to the atherothrombotic processes is unknown.	23880185
Airway structure	Altered Intercellular Communication	Early studies suggested that this might be explained by the presence of heterogeneous airway inflammation.	23880612
Inflammation, Malnutrition	Altered Intercellular Communication	Adiponectin as a novel indicator of malnutrition and inflammation in hemodialysis patients.	23880808
Inflammation, Protein-Energy Malnutrition	Altered Intercellular Communication	Protein-energy malnutrition and inflammation are common and overlapping conditions in hemodialysis patients, which are associated with increased risk of morbidity and mortality.	23880808
Inflammation, Choroidal Neovascularization, Exudate	Altered Intercellular Communication	Probably, vitreomacular adhesion alone is not able to induce age-related macular degeneration, but it may be associated with choroidal neovascularization development, it can contribute to exudate formation and choroidal neovascularization, it may induces or sustains a chronic low-grade inflammation in the macula region.	23882735
Inflammation, Have Shortness of Breath question, Wheezing, Bronchial Hyperreactivity	Altered Intercellular Communication	Asthma is a chronic multifactorial condition racterized by inflammation, bronchial hyperresponsiveness, narrowing of airway associated with wheezing and shortness of breath, where trials have evidenced that approximately 50% despite being on adequate treatment don't achieve optimal control.	23882969
Refractory anemias, Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a complex disease, the hallmark of which is synovial joint inflammation.	23883198
Communicable Diseases, Inflammation, Pseudoaneurysm, Traumatic injury	Altered Intercellular Communication	Disruption of arterial wall integrity as a result of trauma, iatrogeny, inflammation, or infection may result in pseudoaneurysm formation.	23883787
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Sinonasal inflammation and symptoms are often underdiagnosed in chronic obstructive pulmonary disease (COPD) patients.	23883807
Inflammation, Obesity	Altered Intercellular Communication	Assessment of iron deficiency in the context of the obesity epidemic: importance of correcting serum ferritin concentrations for inflammation.	23885047
Inflammation, Overweight	Altered Intercellular Communication	Inflammation (42.3%) was strongly linked with adiposity (20.1%, 37.6%, and 68.4% in normal, overweight, and obese subjects, respectively; P < 0.0001).	23885047
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The colonic mucosal miRNA transcriptome differs significantly between UC and controls, UC and CD, as well as between UC patients with mucosal inflammation and those without.	23885139
Inflammation, Intestinal Obstruction	Altered Intercellular Communication	In magnetic resonance imaging-Sellink, strong inflammation and intestinal obstruction of the terminal ileum were found.	23885155
Orbital Pseudotumor	Altered Intercellular Communication	Very mild infiltration was seen around the Left ophthalmic vein, with no other signs of orbital inflammation.	23885454
Peritonsillar Abscess, Acute suppurative inflammation	Altered Intercellular Communication	Fifty three of them suffered acute suppurative inflammation in the parapharyngeal region that developed as a result of paratonsillar abscess.	23887371
Inflammation	Altered Intercellular Communication	Endothelin (ET)-1 plays a role in vascular reactive oxygen species production and inflammation.	23887640
APP gene, Inflammation, Atherosclerosis	Altered Intercellular Communication	ET-1-induced reactive oxygen species and inflammation may contribute to atherosclerosis progression and AAA development.	23887640
Pterygium Of Conjunctiva And Cornea, Conjunctivitis	Altered Intercellular Communication	Main outcome measures included presence of conjunctival inflammation at 1 month postoperatively as well as recurrence of pterygium.	23887766
Conjunctivitis	Altered Intercellular Communication	At 1 month postoperatively, different grades of conjunctival inflammation were present in 11 (47.8%) of the steroid group and in 14 (56%) of the control group (P=0.39).	23887766
Pterygium Of Conjunctiva And Cornea, Conjunctivitis	Altered Intercellular Communication	In pterygium surgery with a bare-sclera technique and mitomycin C application, intraoperative triamcinolone injection did not significantly reduce postoperative conjunctival inflammation or pterygium recurrence.	23887766
Inflammation, Cerebral Aneurysm, Rupture	Altered Intercellular Communication	Inflammation may play an important role in the formation and rupture of cerebral aneurysms.	23887838
Inflammation, Neutrophil Infiltration	Altered Intercellular Communication	Pathological examination demonstrated necrotizing inflammation with preponderant neutrophil infiltration, variably atypical mononuclear and multinucleate histiocytes, and numerous mitoses.	23889356
Vasculitis of large artery, Giant Cell Arteritis, Arteritis, Occlusion of artery (disorder), Intimal proliferation	Altered Intercellular Communication	Giant cell arteritis is a primary large-vessel vasculitis characterized by an arterial wall inflammation associated with intimal hyperplasia leading to arterial occlusion.	23890680
Inflammation, Polymyositis	Altered Intercellular Communication	Administration of cathepsin B inhibitor CA-074Me reduces inflammation and apoptosis in polymyositis.	23890703
TNF protein, human, Inflammation, Tumor necrosis, Polymyositis, Infiltration	Altered Intercellular Communication	Consistently, the expression of CB, inflammation score, CD8(+) T-cell, CD68(+) cell, tumor necrosis factor-alpha (TNF-a) infiltration and apoptotic rate were significantly increased in the guinea-pig model of CVB1-induced polymyositis.	23890703
Inflammation, Polymyositis	Altered Intercellular Communication	Administration of CA-074Me reduced CB expression, decreased inflammation score and attenuated apoptosis in muscle tissues of the guinea-pig model of CVB1-induced polymyositis.	23890703
Inflammation, Asthma	Altered Intercellular Communication	Fraction of exhaled nitric oxide (Feno) and blood eosinophil count (B-Eos) values, markers of local and systemic eosinophilic inflammation, respectively, are increased in asthmatic patients.	23890753
Tissue damage, Inflammation	Altered Intercellular Communication	Thus, excessive or chronic inflammation initiated by numerous insults exacerbates tissue damage and - at least in some settings - promotes oncogenesis.	23891238
Scleritis, Episcleritis	Altered Intercellular Communication	Incidence of scleritis and episcleritis: results from the Pacific Ocular Inflammation Study.	23891336
Inflammation, Psoriasis, Plaque, Atherosclerotic	Altered Intercellular Communication	Sustained arterial wall inflammation mediated by common cytokines of psoriasis and atherogenesis precedes atherosclerotic plaque development.	23891393
Inflammation, Erythrocytosis	Altered Intercellular Communication	Constitutive excessive erythrocytosis causes inflammation and increased vascular permeability in aged mouse brain.	23892106
Gastrointestinal inflammation	Altered Intercellular Communication	Our findings identify RIP2 as a substrate for Pellino3 and Pellino3 as an important mediator in the Nod2 pathway and regulator of intestinal inflammation.	23892723
Inflammation, Hemorrhage, Edema, Necrosis	Altered Intercellular Communication	Following laparoscopic ileocecectomy, pathology demonstrated haemorrhage, inflammation, oedema and full thickness necrosis of the caecal wall.	23893271
Inflammation, Asthma	Altered Intercellular Communication	YKL-40 (chitinase-3-like-1) has been introduced as a marker of inflammation in asthma.	23893808
Inflammation, Bronchospasm, Inflammatory disorder	Altered Intercellular Communication	Asthma is a chronic inflammatory disorder of the airways, which is diagnosed by periodic symptoms of inflammation, bronchial spasm, and increased mucosal secretions.	23893809
Gingivitis, Dental Plaque, Dental caries	Altered Intercellular Communication	Dental plaque, gingival inflammation, mouth breathing, and dental caries were evaluated by one trained examiner according to World Health Organization [WHO] criteria.	23893809
allergic inflammation, Respiratory Tract Infections, Infection, Atopy	Altered Intercellular Communication	Allergic inflammation may influence the immunity against infections, so atopic individuals could be susceptible to respiratory infections.	23894319
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Chronic inflammation contributes to cardiac fibrosis, a crucial factor in HFpEF; however, inflammatory mechanisms and mediators involved in the development of HFpEF remain unclear.	23894370
Inflammation, Oral infection, Cardiovascular Diseases	Altered Intercellular Communication	The possible association between oral infection and chronic inflammation and cardiovascular disease risk has been studied intensively.	23895250
Granuloma, Inflammation, Granuloma Annulare, Necrosis	Altered Intercellular Communication	Excisional biopsy revealed ill-defined granulomas with central necrosis, chronic inflammation and sclerotic collagen; several features consistent with granuloma annulare.	23895369
Inflammation, Ascites	Altered Intercellular Communication	Laboratory examinations revealed marked inflammation, and abdominal computed tomography showed diffuse thickening of the small intestinal wall and peritoneum, and soft tissue infiltration of the mesentery, without ascites.	23898495
Inflammation, Cerebral Ischemia	Altered Intercellular Communication	Together, our data suggest that SIRT6 may serve as a potential therapeutic target for HMGB1-mediated inflammation after cerebral ischemia.	23899523
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Telomerase as a potential marker for inflammation and cancer detection in bronchial washing: a prospective study.	23899579
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Random 82 bronchial aspirates were obtained from patients undergoing bronchoscopy to diagnose any lung illness including inflammation and cancer.	23899579
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	A significant difference in telomerase activity average was noted between normal patients and those with inflammation and cancer.	23899579
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Discriminatory capacity of telomerase activity was: for cancer vs. non cancer, AUC =0.74 (95% CI: 0.62-0.84), sensitivity=78%, specificity=72%, Negative Predictive Value=87%, at cut-off >0.46 atmol/mg protein/20 min; for cancer vs. normal, AUC=0.87 (95% CI: 0.72-0.96), se=78%, sp=92%, NPV=71%, at cut-off >0.46; for cancer vs. inflammation, AUC=0.69 (95% CI: 0.55-0.80), se=74%, sp=70%, NPV=79%, at cut-off >1.03, and for inflammation vs. normal, AUC=0.76 (95% CI: 0.62-0.88), se=79%, sp=77%, NPV=59%, at cut-off >0.	23899579
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Telomerase activity in bronchial aspirates is a promising diagnostic marker for lung cancer and inflammation detection.	23899579
Inflammation	Altered Intercellular Communication	Angiopoietin-2 (Angpt-2), a marker of endothelial cell activation, has been proposed as a mediator of angiogenesis, which might play an important role in the regulation of endothelial integrity and inflammation.	23899926
Pulmonary arterial hypertension, Inflammation, Polycyclic Hydrocarbons, Aromatic	Altered Intercellular Communication	Pulmonary arterial hypertension (PAH) is a disease of progressive vascular remodeling, characterized by dysregulated growth of pulmonary vascular cells and inflammation.	23900048
Granulomatous inflammation, Carcinoma, Papillary, Medullary carcinoma	Altered Intercellular Communication	Simultaneous medullary carcinoma, papillary carcinoma and granulomatous inflammation of the thyroid.	23900477
Granulomatous inflammation, Thyroid carcinoma, Neoplasm Metastasis, C-cell hyperplasia of thyroid	Altered Intercellular Communication	We herein report the case of a 35-year-old man with a mixed medullary-papillary carcinoma of the thyroid, which presented with C-cell hyperplasia, granulomatous inflammation and metastasis to the cervical lymph nodes.	23900477
Inflammation	Altered Intercellular Communication	In conclusion, the increase of IL-6 in relation to the duration of the intubation indicates an increased risk of inflammation.	23900683
Inflammation, Neoplasms, Pathology, Vascular lesions, TDP-43 Proteinopathies, Brain Diseases, Metabolic	Altered Intercellular Communication	Further pathologies included a-synucleinopathies (24.9 %), non-Alzheimer tauopathies (23.2 %; including novel forms), TDP-43 proteinopathy (13.3 %), vascular lesions (48.9 %), and others (15.1 %; inflammation, metabolic encephalopathy, and tumours).	23900711
Inflammation, Nasal Polyps, Nasal congestion (finding)	Altered Intercellular Communication	Oral plus nasal corticosteroids improve smell, nasal congestion, and inflammation in sino-nasal polyposis.	23901043
Eosinophilic disorder, Nasal inflammation, Nasal congestion (finding)	Altered Intercellular Communication	Combined oral and intranasal corticosteroids improve smell and nasal congestion and decrease nasal inflammation, as measured by reduced tissue eosinophilia and increased detection of nNO.	23901043
Eosinophilic disorder, Inflammation, Anosmia, Nasal congestion (finding)	Altered Intercellular Communication	Severity of smell loss correlates with degree of nasal congestion but not with inflammation, as measured by tissue eosinophilia or nasally exhaled nNO.	23901043
Inflammation, Guillain-Barre Syndrome, Familial	Altered Intercellular Communication	Here, we analyze the role of human group IIA secreted phospholipase A2 (sPLA2-IIA), a bactericidal enzyme induced during acute inflammation, in innate immunity against GBS.	23901095
Inflammatory Bowel Diseases, Inflammation, Dysplasia, Carcinoma	Altered Intercellular Communication	NTSR1 in colonic epithelial cells is overexpressed in IBD, in a stepwise fashion with sequential progress from inflammation to dysplasia and carcinoma.	23901225
Inflammation, Ulcer	Altered Intercellular Communication	Levels of MMP-9 or TIMP-1 at the ulcer site were associated with the histological severity of activity and inflammation.	23901237
Hypernatremia, Inflammation, Hypertension, CTCAE, Electrocardiogram: left ventricle hypertrophy (finding)	Altered Intercellular Communication	Hypertension, fluid overload and micro inflammation are associated with left ventricular hypertrophy in maintenance hemodialysis patients.	23901794
Hypernatremia, Inflammation, Left Ventricular Hypertrophy, HD Term Type, Hypertension, CTCAE	Altered Intercellular Communication	These data support the main conclusions: hypertension, fluid overload and micro inflammation are associated with LVH in maintenance HD patients.	23901794
Inflammation, Cachexia	Altered Intercellular Communication	Experimental models of cancer cachexia have indicated that systemic inflammation induces muscle-protein breakdown and wasting via muscular nuclear transcription factor kB (NF-kB) activation.	23902785
Inflammation, Cachexia	Altered Intercellular Communication	Systemic and local inflammation was evident in cachexia and intermediate in precachexia, but the plasma of both patients groups caused ex vivo muscle NF-kB activation.	23902785
Inflammation, Heart failure, Depression, CTCAE	Altered Intercellular Communication	Researchers have proposed biological (inflammation) and psychological (depression) factors as potential mechanisms for poorer outcomes and readmissions in heart failure (HF) patients.	23904128
Inflammation, Bipolar Disorder	Altered Intercellular Communication	However, studies investigating the link between inflammation and depressive symptoms in these patients are few.	23904128
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Our findings add to a growing body of evidence supporting the proposition that heightened inflammation explains the effect depression has on HF.	23904128
Inflammation, hafnium, Depression, CTCAE	Altered Intercellular Communication	Health care providers should screen for depression in HF patients, as they may be at higher risk of augmented inflammation and poor outcomes.	23904128
Phagocyte Bactericidal Dysfunction, Musculoskeletal Pain	Altered Intercellular Communication	Phagocyte dysfunction in polymyalgia rheumatica and other age-related, chronic, inflammatory conditions.	23904438
Inflammation, Arteriovenous fistula	Altered Intercellular Communication	The relationship between arteriovenous fistula success and inflammation.	23906289
Kidney Failure, Chronic, HD Term Type, Inflammation, Electronic Source Report Form	Altered Intercellular Communication	In this study, the relationship between AVF success and inflammation in patients who had HD due to end-stage renal failure (ESRF) was investigated.	23906289
HD Term Type, Inflammation	Altered Intercellular Communication	As a result, we think that the evaluation of inflammation before creating AVF in HD patients is very important for increasing the success of AVF.	23906289
Mesenteric Panniculitis, Hyperplastic Polyp	Altered Intercellular Communication	Mesenteric panniculitis (MP) is an underdiagnosed inflammatory condition of mesenteric adipose tissue.	23906444
Inflammation, Cardiac Death	Altered Intercellular Communication	Inflammation and sudden cardiac death in a community-based population of older adults: the Cardiovascular Health Study.	23906927
Inflammation, Cardiac Death, SLC22A5 gene	Altered Intercellular Communication	Inflammation is linked to adverse cardiovascular events, but its association with sudden cardiac death (SCD) has been controversial.	23906927
Inflammation, SLC22A5 gene	Altered Intercellular Communication	The purpose of this study was to study the association between inflammation and SCD in a community-based population of older adults.	23906927
Inflammation, Electrocardiogram: myocardial infarction (finding), Heart failure, SLC22A5 gene	Altered Intercellular Communication	Greater burden of inflammation, assessed by IL-6 levels, is associated with SCD risk beyond traditional risk factors, incident myocardial infarction, and heart failure.	23906927
Communicable Diseases, Inflammation, Connective Tissue Diseases, Aneurysm	Altered Intercellular Communication	A histopathological examination of the aneurysm wall did not detect any significant background factors, such as connective tissue disease, inflammation or infection.	23906964
Inflammation, neuron death	Altered Intercellular Communication	Treadmill exercise represses neuronal cell death and inflammation during Ab-induced ER stress by regulating unfolded protein response in aged presenilin 2 mutant mice.	23907580
Neurodegenerative Disorders, Inflammation, Data types - Address, Apoptosis of neurons	Altered Intercellular Communication	ER stress is involved in neurodegenerative diseases including AD, but the molecular mechanisms of neuronal apoptosis and inflammation by Ab-induced ER stress to exercise training are not fully understood.	23907580
Inflammation, Atherosclerosis	Altered Intercellular Communication	Cyclooxygenase-2 (COX-2) catalyzes the formation of prostaglandins that contribute to the inflammation in atherosclerosis.	23907768
Inflammation, Neoplasm Metastasis, Tuberculosis	Altered Intercellular Communication	We present a unique case of disseminated tuberculosis presenting initially in the eye solely as a choroidal mass without any inflammation, mimicking choroidal metastasis.	23907976
Granulomatous inflammation	Altered Intercellular Communication	Fine needle aspiration cytology of the adnexal mass and ascitic fluid revealed granulomatous inflammation with a negative acid-fast bacilli stain.	23907976
Airway structure, Protease Inhibitors	Altered Intercellular Communication	25-hydroxyvitamin D (25(OH)D) may be associated with lung function through modulation of pulmonary protease-antiprotease imbalance, airway inflammation, lung remodelling and oxidative stress.	23908128
Fibrosis Assessment, Metabolic Syndrome X, prostatitis	Altered Intercellular Communication	Metabolic syndrome correlates with peri-urethral fibrosis secondary to chronic prostate inflammation: evidence of a link in a cohort of patients undergoing radical prostatectomy.	23909794
Fibrosis Assessment, Metabolic Syndrome X, prostatitis	Altered Intercellular Communication	To investigate the pathological relationship between metabolic syndrome and peri-urethral fibrosis status secondary to chronic prostate inflammation.	23909794
Symptoms, Inflammation, Bladder neck obstruction	Altered Intercellular Communication	A positive correlation was observed between inflammation, International Prostatic Symptoms Score, Bladder Outlet Obstruction Index and collagen amount, whereas inflammation was inversely correlated with elastin amount.	23909794
Fibrosis Assessment, Metabolic Syndrome X, prostatitis	Altered Intercellular Communication	On multivariate logistic regression analysis, prostate inflammation and metabolic syndrome were the only independent predictors of peri-urethral fibrosis (OR 1.73, 1.52, respectively).	23909794
Inflammation, Metabolic Syndrome X, prostatitis	Altered Intercellular Communication	The present findings suggest that metabolic syndrome might represent an independent risk factor for prostate inflammation and fibrotic changes secondary to inflammation within the peri-urethral prostatic tissue.	23909794
palladium, Peyronie Disease	Altered Intercellular Communication	Several studies describing the "natural history" of Peyronie's disease (PD) (Chronic Inflammation of the Tunica Albuginea-CITA) showed that untreated patients with PD seem to have spontaneous improvement.	23909888
Inflammation, Primary Biliary Cholangitis	Altered Intercellular Communication	Thus, IL-23 and IL-17 may play an important role in the pathogenesis of PBC by promoting inflammation.	23910013
Diabetes Mellitus, Insulin-Dependent, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8	Altered Intercellular Communication	The neurotransmitter Neuropeptide Y (NPY) was previously reported as a minor autoantigen in newly diagnosed type 1 diabetes (T1D) patients.	23910631
Sinusitis	Altered Intercellular Communication	But nasal and paranasal sinus inflammation is the relative contraindications of TSA.	23911235
Inflammation, Fibrosis Assessment, Granuloma	Altered Intercellular Communication	The histopathological evaluation comprised myofibroblast foci (MF), intensity of inflammation and fibrosis (Ashcroft score) and numbers of eosinophils and granulomas.	23911740
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Alveolar macrophages produce neutrophil chemoattractants; this cellular cross-talk contributes to neutrophilic airway inflammation in chronic obstructive pulmonary disease (COPD).	23912333
Fibrosis Assessment, Hepatotoxicity, Cholestasis, Fatty degeneration	Altered Intercellular Communication	Specific transcriptomic hepatotoxicity signatures were created for CPZ and consisted of inflammation/hepatitis, cholestasis, and liver proliferation in all five donors, as well as fibrosis and steatosis, which were observed in four of five donors.	23913027
Inflammation, Uveitis, Systemic disease, Herpes Zoster Ophthalmicus	Altered Intercellular Communication	Despite their side-effects and the advent of systemic immunosuppressives and biologics, the use of corticosteroids remains in the management of patients with uveitis, particularly when inflammation is associated with systemic disease or when bilateral ocular disease is present.	23914773
Inflammation	Altered Intercellular Communication	Perceiving ambivalence toward one's spouse in a support context was linked to greater inflammation even when considering health behaviors, relationship-specific romantic attachment style, spouse negativity/positivity ratings, and overall marital satisfaction.	23914811
Inflammation, Perforation of pharynx	Altered Intercellular Communication	Even though she had received conservative treatment, exacerbation of inflammation was observed and therefore we performed transoral surgery for closing the pharyngeal perforation.	23916242
Inflammation, Perforation of pharynx	Altered Intercellular Communication	The pharyngeal perforation smoothly closed and exacerbation of inflammation was not observed, even after oral ingestion began.	23916242
mucosa-associated lymphoid tissue, Lymphoma, Lymphoproliferative Disorders, Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	Of the 1,014 cases of orbital lymphoproliferative disorders 404 (39.8 %) had extranodal mucosa-associated lymphoid tissue (MALT) lymphoma, 156 (15.4 %) had other malignant lymphomas, 191 (18.8 %) had non-IgG4 orbital inflammation, 219 (21.6 %) had IgG4-related orbital inflammation, and 44 (4.3 %) had IgG4-positive MALT lymphoma.	23917985
Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	Median age of the IgG4-related orbital inflammation group was 62 years, which is significantly lower than that of the MALT lymphoma group (median 66 years) and higher than the non-IgG4 orbital inflammation group (median 57 years).	23917985
Inflammation, Chronic Obstructive Airway Disease, Carcinoma of lung	Altered Intercellular Communication	Local and systemic neutrophilic inflammation in patients with lung cancer and chronic obstructive pulmonary disease.	23919722
ARCN1 gene, Inflammation, Carcinoma of lung	Altered Intercellular Communication	The results from this study demonstrate higher degree of local and systemic neutrophilic inflammation in patients with lung cancer (with or without COPD) than in patients with COPD.	23919722
Inflammation, Asthma, Depression, CTCAE	Altered Intercellular Communication	Children with both asthma and depression are at risk for heightened inflammation.	23919906
Asthma, Depression, CTCAE	Altered Intercellular Communication	To test whether children and adolescents with co-occurring asthma and depression are at risk for elevated inflammation-concurrently and at the next assessment.	23919906
Inflammation, Asthma, Depression, CTCAE, Chronic disease	Altered Intercellular Communication	The co-occurrence of asthma and depression in childhood poses a risk for substantially elevated inflammation concurrently and over time, which could contribute to pathophysiological processes involved in the development of additional chronic diseases and also to asthma--related morbidity and mortality.	23919906
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	S100A12 induces vascular inflammation contributing to the development of atherosclerosis.	23921255
Airway structure, Asthma, Obesity	Altered Intercellular Communication	We found a positive correlation between BMI and FeNO level which suggests a link between obesity and increased airway inflammation in nonasthmatic children.	23921526
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Local inflammation after tubal ligation may affect ovarian function and breast cancer risk.	23922107
Inflammation, GDC Disease Response Terminology	Altered Intercellular Communication	Various cytokines associated with inflammation and angiogenesis may contribute to the pathogenesis of DR, and chemokines may be more closely related to the development of this disease.	23922491
Inflammation	Altered Intercellular Communication	Retinal vascular caliber is associated with cardiovascular biomarkers of oxidative stress and inflammation: the POLA study.	23923054
Inflammation	Altered Intercellular Communication	This case provides insight into the potential role of chronic inflammation and genetic instability in the pathogenesis of BIA-ALCL.	23923082
Inflammation, Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	Low-grade inflammation of the intestine may be one of the reasons for development of diarrhoea-predominant IBS (IBS-D).	23923350
Inflammation	Altered Intercellular Communication	Our results indicate that mild inflammation is involved in IBS-D patients as proinflammatory cytokines were increased although no difference in anti-inflammatory cytokine was observed.	23923350
Tubulitis Assessment, Inflammation, Interstitial inflammation	Altered Intercellular Communication	On the protocol biopsies, interstitial inflammation (Banff i scores) and tubulitis (Banff t scores) were more likely in the r-ATG group at one month, but at four and 12 months, both inflammation and tubulitis were more likely in the alemtuzumab group.	23924146
Pain Distress Question, Endophthalmitis, CTCAE, Inflammation	Altered Intercellular Communication	However, normal post-operative pain and inflammation may mask endophthalmitis and lead to delayed diagnosis and grave visual consequences.	23924462
Inflammation, Chronic disease	Altered Intercellular Communication	Intense marrow iron examination provides a useful iron status classification which is of particular importance in cases of chronic diseases and inflammation.	23924552
Inflammation, Inflammatory Myofibroblastic Tumor	Altered Intercellular Communication	The presence of ALK-1 positivity within the spindle cells, coupled with the prominent inflammation indicated a diagnosis of ALK-1 positive inflammatory myofibroblastic tumour (IMT-the neoplastic member of the so called inflammatory pseudotumours).	23927068
Inflammation, Ischemia	Altered Intercellular Communication	Oxidation of unsaturated lipids generates reactive aldehydes that accumulate in tissues during inflammation, ischemia, or aging.	23928303
Inflammation, Obesity	Altered Intercellular Communication	Severe obesity is associated with a state of chronic inflammation.	23928404
Inflammation, Weight decreased	Altered Intercellular Communication	Extensive weight loss increases sirtuin expression significantly both in adipose tissue and liver, probably as a consequence of reduced inflammation.	23928404
Inflammation, Anemia, Chronic Kidney Diseases, Diabetes Mellitus	Altered Intercellular Communication	Multivariate regression model revealed RDW as a significant predictor of FMD independent of major confounding factors, such as diabetes, inflammation, anemia and kidney function in CKD.	23928544
Inflammation, Calcinosis	Altered Intercellular Communication	Aortic valve (AV) calcification occurs via a pathophysiological process that includes lipoprotein deposition, inflammation, and osteoblastic differentiation of valvular interstitial cells.	23928865
Inflammation, Malnutrition, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Malnutrition and/or inflammation may modify the risk relationship of total cholesterol with cardiovascular disease in CKD patients.	23929929
Inflammation	Altered Intercellular Communication	With Masson staining, there was increased connective tissue and no inflammation.	23930362
Communicable Diseases, Inflammation	Altered Intercellular Communication	A low prime volume is expected to improve blood conservation and decrease donor exposure, prevent drawbacks of transfusion (immunomodulation, infection), increase the incidence of blood-free surgery in smaller babies, and decrease whole body systemic inflammation by decreasing surface of foreign material in contact with blood and inflammation associated with blood transfusion.	23930382
Inflammation	Altered Intercellular Communication	Chronic traffic pollution exposure is associated with eosinophilic, but not neutrophilic inflammation in older adult asthmatics.	23931679
Inflammation, Asthma	Altered Intercellular Communication	Poorly controlled asthma in older adults is associated with eosinophilic and neutrophilic inflammation.	23931679
Inflammation	Altered Intercellular Communication	Chronic residential traffic pollution exposure may be associated with eosinophilic, but not neutrophilic inflammation in older asthmatics.	23931679
Inflammation, Neoplasms	Altered Intercellular Communication	He underwent urgent resection and histological examination revealed tumor cells in a mucopolysaccharide matrix and bacterial colonies along with active inflammation.	23931763
Inflammation, Disorder of tendon	Altered Intercellular Communication	Peritendinous injection of corticosteroid is the commonly accepted strategy despite the absence of inflammation in tendinopathy.	23931981
Refractory anemias, Inflammation	Altered Intercellular Communication	TCZ8 strongly inhibited the biomarkers of joint tissue remodeling suggesting that TCZ actively suppresses key pathobiological processes at the site of inflammation in RA patients.	23932312
Inflammation	Altered Intercellular Communication	We examined thrombospondin-1 (THBS1, alias TSP-1) expression in human synovial tissue (ST) during the resolution phase of chronic inflammation and elucidated its transcriptional regulation by the orphan receptor 4A2 (NR4A2).	23933487
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Although histological steatosis, inflammation, and fibrosis did not change after treatment, liver fibrosis improved in seven patients (41.2%), progressed in five (29.4%), and remained unchanged in five (29.4%).	23933938
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Linear regression analysis confirmed an independent association of liver fibrosis, steatosis, inflammation, and hepatocyte ballooning with hepatic chemerin mRNA expression (P<0.05 respectively).	23935128
Hepatitis, Fatty Liver Disease	Altered Intercellular Communication	This is the first study to show that chemerin mRNA expression is significantly elevated in the liver of NASH patients and that CMKLR1 expression is upregulated in liver inflammation, whereby IL6 could play a causal role.	23935128
Sepsis, Inflammation, Multiple Organ Failure, physiopathological	Altered Intercellular Communication	In systemic inflammation and sepsis, endothelial activation and microvascular dysfunction are characteristic features that promote multiorgan failure.	23935249
Single organ dysfunction, Inflammation	Altered Intercellular Communication	SDMA levels closely correlated with disease severity scores, biomarkers of inflammation, and organ failure (renal, hepatic, and circulatory).	23935249
Non-alcoholic Fatty Liver Disease, Inflammation, Liver damage	Altered Intercellular Communication	Meanwhile, among subjects with NAFLD, index of liver damage, such as elevated ALT combined with genetic susceptibility to inflammation associated with increased SUA levels.	23935829
Inflammation, Ischemia	Altered Intercellular Communication	Inflammation occurring in the central nervous system (CNS) in association with ischemia is caused by immune cells including monocytes and involved in lesion expansion.	23936327
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	We showed that atherosclerotic plaque areas in the AngII-infused Apo E KO mice and markers of inflammation such as RAGE, ICAM-1, VCAM-1, and MCP-1 were increased in aorta compared to that of the Apo E KO mice.	23936343
Long-Term Synaptic Depression, Depression, CTCAE	Altered Intercellular Communication	These mice also show significant abnormalities in basal synaptic transmission, paired-pulse facilitation and long-term depression (LTD).	23936403
AICARDI-GOUTIERES SYNDROME, Gastritis	Altered Intercellular Communication	To identify the contributions of g-glutamyltranspeptidase and asparaginase to gastric cell inflammation, human gastric epithelial cells (AGS line) were infected with H. pylori wild-type and knockout strains and inflammatory responses evaluated by induction of interleukin-8 (IL-8).	23937242
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	These data suggest that g-glutamyltranspeptidase plays a significant role in the chronic inflammation caused by H. pylori infection.	23937242
Inflammation	Altered Intercellular Communication	Epicardial adipose tissue (EAT), deposited around subepicardial coronary vessels, may contribute directly to perivascular inflammation and smooth muscle cell proliferation.	23937273
Immunocompromised Host	Altered Intercellular Communication	We report an exaggerated dermatological inflammatory condition in an immunocompromised patient.	23937292
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	When CT shows focal inflammation anywhere within the abdomen, along with an abnormal SMA/SMV relationship, the position of the caecum should be ascertained and acute appendicitis ruled out.	23937823
Inflammation, Malignant Neoplasms, Necrosis	Altered Intercellular Communication	Necrosis is a common feature of various malignant tumors, which also has two opposing effects: pro-tumor by chronic inflammation and anti-tumor by effective cell clearance.	23938031
Primary malignant neoplasm	Altered Intercellular Communication	Prognostic factors in patients with advanced cancer: a comparison of clinicopathological factors and the development of an inflammation-based prognostic system.	23938289
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Biomarkers of systemic inflammation may have prognostic value in advanced cancer.	23938289
Primary malignant neoplasm	Altered Intercellular Communication	A systemic inflammation-based score, mGPS, and performance status predict survival in advanced cancer.	23938289
Inflammation, Tissue injury	Altered Intercellular Communication	The principal findings revealed almost exclusive inflammation and tissue injury in the hypothalamus.	23939463
Inflammation	Altered Intercellular Communication	Inflammation was associated with complete loss of hypocretinergic neurons.	23939463
Candida albicans, Inflammation, Candida (fungus)	Altered Intercellular Communication	Oral mucosa inflammation other than irradiation is mostly caused by Candida albicans, yeast of Candida genus.	23940987
Inflammation, Hepatitis B, Hepatocarcinogenesis	Altered Intercellular Communication	Persistent inflammation together with genetic/epigenetic aberrations is strongly associated with chronic Hepatitis B virus (HBV) infection-related hepatocarcinogenesis.	23941364
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Synovial fluid levels of bradykinin correlate with biochemical markers for cartilage degradation and inflammation in knee osteoarthritis.	23942063
Degenerative polyarthritis, Inflammation, Osteoarthritis, Knee	Altered Intercellular Communication	To determine the content of bradykinin (BK) and markers of cartilage degradation and inflammation in the synovial fluid (SF) of patients with knee osteoarthritis (OA), and to evaluate correlations with biomarkers or clinical parameters.	23942063
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The presence of BK in the knee OA SF and its correlations with cartilage degradation and inflammation markers of OA support its participation in OA pathology.	23942063
Ischemic stroke	Altered Intercellular Communication	An association between poor oral health and an increased risk of ischaemic stroke has been recognised through the oral infection-inflammation pathway.	23942139
Inflammation, Lower gastrointestinal hemorrhage, Endothelial dysfunction, Depression, CTCAE	Altered Intercellular Communication	Endothelial dysfunction (ED), low-grade inflammation (LGI) and oxidative stress (OxS) may be involved in the pathobiology of depression.	23942242
Inflammation, Obesity	Altered Intercellular Communication	Macrophage infiltration into adipose tissue during obesity and their phenotypic conversion from anti-inflammatory M2 to proinflammatory M1 subtype significantly contributes to develop a link between inflammation and insulin resistance; signaling molecule(s) for these events, however, remains poorly understood.	23943623
Alzheimers Disease", Inflammation Mediators, Nerve Degeneration	Altered Intercellular Communication	The results suggest that, in the long term, amyloid-b immunotherapy results in downregulation of microglial activation and potentially reduces the inflammation-mediated component of the neurodegeneration of Alzheimer's disease.	23943781
Inflammation	Altered Intercellular Communication	The mechanisms underlying the involvement of the complement system are not understood, although complement and inflammation have been implicated in drusen formation.	23943789
Inflammation	Altered Intercellular Communication	The NLRP-3 (nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3) inflammasome has recently emerged as a pivotal regulator of chronic inflammation.	23944632
Inflammation	Altered Intercellular Communication	Because anti-Neu5Gc Abs can promote chronic inflammation, the long-term safety of living and acellular pig tissue implants in recipients warrants further evaluation.	23945141
Sample Size Calculation	Altered Intercellular Communication	Biomarkers of inflammation/endothelial activation were generally increased among SSc patients.	23945149
Inflammation, Neoplasms	Altered Intercellular Communication	Chronic inflammation has been recognized to foster tumour development.	23945200
Inflammation, Abscess of testis	Altered Intercellular Communication	[A case of testicular abscess with low-grade inflammation].	23945330
Inflammation, Abscess of testis	Altered Intercellular Communication	We report a case of testicular abscess with low-grade inflammation.	23945330
Inflammation	Altered Intercellular Communication	The clinical course of this case was unusual because of the small extent of inflammation observed.	23945330
Inflammation, Abscess of testis	Altered Intercellular Communication	Typically, testicular abscess is characterized by severe systemic and local inflammation.	23945330
Inflammation, Inflammatory abnormality of the eye	Altered Intercellular Communication	To evaluate the high-speed anterior segment optical coherence tomography (AS-OCT) grading of the AS inflammation in patients with ocular inflammation.	23945636
Granulomatous inflammation	Altered Intercellular Communication	Histopathological study of the resected adenoid revealed caseating granulomatous inflammation.	23946986
Communicable Diseases, Inflammation, Optic Neuritis	Altered Intercellular Communication	Optic neuritis is an acute inflammation of the optic nerve and, in its atypical form, is caused by inflammation of the optic nerve as part of infectious, immune, granulomatous, or contiguity processes.	23947007
Communicable Diseases, Inflammation	Altered Intercellular Communication	We hypothesized that DNA condensation by cationic polypeptides in CF sputum would result in a better control of CF inflammation and infection.	23947381
Pseudomonas aeruginosa, Inflammation	Altered Intercellular Communication	It retains antimicrobial properties against Pseudomonas aeruginosa and Staphylococcus aureus at doses that induce no inflammation in the mouse lung after aerosol administration.	23947381
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Clinical experience with intravenous administration of ascorbic acid: achievable levels in blood for different states of inflammation and disease in cancer patients.	23947403
Inflammation, Neoplasms	Altered Intercellular Communication	The data indicate that, while potentially therapeutic plasma ascorbate concentrations can be achieved with IVC, levels attained will vary based on tumor burden and degree of inflammation (among other factors).	23947403
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Evidence suggests that IVC may be able to modulate inflammation, which in turn might improve outcomes for cancer patients.	23947403
Inflammation, Bursitis	Altered Intercellular Communication	Iliopsoas bursitis (IB) is characterized by inflammation and enlargement of the iliopsoas bursa.	23948843
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Synaptic alterations are reported to be seen in Alzheimer's disease (AD) and the suggested function of SLC10A4 as a vesicular transporter for cholinergic neurotransmitters proposes a link between this protein and AD.	23948907
Inflammation, Necrosis	Altered Intercellular Communication	Mild chronic inflammation, hemosiderin, and coagulative necrosis were also observed.	23948957
Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is one of the most common autoimmune diseases that result in chronic inflammation of the joints.	23949659
vascular inflammations	Altered Intercellular Communication	This may identify IL-19 as a novel therapeutic to limit vascular inflammation.	23950143
Pain Distress Question, Myelitis, neuromyelitis	Altered Intercellular Communication	Although spinal cord inflammation is a defining aspect of neuromyelitis, there is an almost complete lack of data on altered somatosensory function, including pain.	23951176
Inflammation, Endothelial dysfunction, Cardiovascular Diseases	Altered Intercellular Communication	Elevated plasma levels of asymmetric dimethylarginine (ADMA) have been reported to be associated with endothelial dysfunction, inflammation, and oxidative stress in multiple cardiovascular diseases.	23951217
Inflammation, Arthropathy	Altered Intercellular Communication	This exploratory investigation featuring a variety of joint disorders revealed that measuring the relative proportions of inflammatory cell types may aid in synovial tissue classification if the samples are also stratified according to the intensity of inflammation.	23951325
Inflammation, Chagas Disease, Liver damage	Altered Intercellular Communication	We investigated the pathological and diagnostic role of selected markers of inflammation, oxidant/antioxidant status, and cellular injury in human Chagas disease.	23951383
Gastroesophageal reflux disease, Inflammation	Altered Intercellular Communication	High levels of fractions of sialic acids were set, that was associated with the protein fructose, fractions of hydroxyproline in children with GERD compared with the patients with DG, which testify to the process of degradation of collagen and may be one of the factors contributing to the local inflammation of the esophagus and gastroduodenal zone of the digestive tract.	23951893
Inflammation, Dyslipidemias	Altered Intercellular Communication	The features of proatherogenic disorders connected with dominating types of dyslipidemias, the degree of chronic inflammation manifestation and some results of hormonal background were established for people with certain reproductive status.	23951911
Inflammation, Dyslipidemias	Altered Intercellular Communication	The features of proatherogenic disorders connected with dominating types of dyslipidemias, the degree of chronic inflammation manifestation and some results of hormonal background were established for people with certain reproductive status.	23951911
Inflammation	Altered Intercellular Communication	Pentraxin-3 (PTX3) is a multifactorial protein involved in immunity and inflammation, which is rapidly produced and released by several cell types in response to inflammatory signals.	23952075
Inflammation	Altered Intercellular Communication	It may be suggested that PTX3 is related with periodontal tissue inflammation.	23952075
Inflammation	Altered Intercellular Communication	Pentraxin-3 (PTX3) is a multifactorial protein involved in immunity and inflammation, which is rapidly produced and released by several cell types in response to inflammatory signals.	23952075
Hypertensive disease, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	[Effect of perindopril on the processes of subclinical inflammation in patients with arterial hypertension and type 2 diabetes mellitus].	23952947
ARCN1 gene, Inflammation, Carcinoma of lung	Altered Intercellular Communication	Oxidative stress and inflammation in the normal airways and blood of patients with lung cancer and COPD.	23954470
ARCN1 gene, Inflammation	Altered Intercellular Communication	Regardless of the presence of an underlying respiratory condition (COPD), protein oxidation, oxidatively damaged DNA, and inflammation were remarkably increased in the normal airways and blood of patients with LC.	23954470
Inflammation, Rheumatic Heart Disease	Altered Intercellular Communication	Aberrantly high levels of CD306 were found in the sera of pregnant women and patients with inflammation and rheumatic heart disease and in the urine of pregnant women.	23954474
Inflammation, Vascular calcification	Altered Intercellular Communication	Vascular calcifications and bone health seem to be etiologically linked via common risk factors such as aging and subclinical chronic inflammation.	23954758
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	Cystatin C was associated with the severity of regurgitation independent of renal function body composition chronic inflammation LV remodeling and diastolic function in hypertensive patients with mild-to-moderate AR.	23954770
Barrett Esophagus, Inflammation, Adenocarcinoma Of Esophagus	Altered Intercellular Communication	Barrett's esophagus (BE) is known to progress to esophageal adenocarcinoma in a setting of chronic inflammation.	23955118
Carcinogenesis	Altered Intercellular Communication	Toll-like receptor (TLR) 4 has been linked to inflammation-associated carcinogenesis.	23955118
Inflammation, Anastomosis - action	Altered Intercellular Communication	These findings suggest that barium was embedded in the submucosa and lamina propria with manipulation of the stapled anastomosis and that the barium trapped in the anastomotic site caused persistent inflammation, resulting in an anastomotic stricture.	23955478
Tissue damage, Inflammation	Altered Intercellular Communication	High-sensitivity C-reactive protein (hs-CRP) is an extremely sensitive systemic marker of inflammation and tissue damage, and increased levels of hs-CRP are strongly associated with inflammatory reactions.	23955613
palladium, Inflammation, Presenile dementia	Altered Intercellular Communication	It is known that inflammation plays a role in the pathogenesis of PD and dementia.	23955613
Inflammation, Asthma, Respiratory Hypersensitivity, Congenital Abnormality	Altered Intercellular Communication	Subjects with asthma with (3)He ventilation defects were older with significantly worse airway hyper-responsiveness, inflammation and airway remodelling but similar FEV1 as subjects with asthma without defects; hyperpolarised (3)He ventilation abnormalities were spatially and quantitatively related to abnormally remodelled airways.	23956019
Saint Lucia, GDC Molecular Consequence Terminology, Acute and chronic inflammation, Colitis	Altered Intercellular Communication	Dysregulated T cell responses in the intestine may lead to chronic bowel inflammation such as collagenous colitis (CC) and lymphocytic colitis (LC), together known as microscopic colitis (MC).	23956982
Inflammation	Altered Intercellular Communication	AGEs have been shown to contribute to chronic inflammation and oxidative stress in humans.	23957669
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Interactions between DCs and regulatory T cells (Treg), which regulate immune response by attenuating acute inflammation, are postulated to be involved in the pathogenesis of autoimmune diseases.	23958259
Inflammation	Altered Intercellular Communication	The results of our study provide novel insights in the direct interaction of mature DCs and Treg in plaque inflammation and stability.	23958259
HD Term Type, Inflammation	Altered Intercellular Communication	We hypothesized that the association of low IGF-1 with chronic inflammation may increase the mortality risk in HD patients.	23958273
Inflammation	Altered Intercellular Communication	It is suggested that local activation of these sensory nerves may involve dural mast cells as one factor in local inflammation, causing sensitization of meningeal nociceptors.	23958278
Toxic nephropathy, Nephritis	Altered Intercellular Communication	Moreover, renal inflammation is observed in CNI nephrotoxicity but the mechanisms are poorly understood.	23958496
Degenerative polyarthritis, Inflammation, Degenerative disorder of cartilage	Altered Intercellular Communication	Osteoarthritis (OA) is a complex disease characterized by cartilage degeneration, secondary synovial membrane inflammation and subchondral bone changes.	23958877
Inflammation, Hepatitis C, Liver Cirrhosis, Diabetes Mellitus	Altered Intercellular Communication	In hepatitis C, continuous inflammation mediated by TNF-a leads to liver cirrhosis and diabetes mellitus.	23961783
Inflammation, Hypertension, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	HCV+ psoriatic patients were less obese, but still had a higher frequency of diabetes mellitus and hypertension, possibly due to chronic inflammation in the liver and other organs.	23961783
Inflammation	Altered Intercellular Communication	Elevated MMP-to-TIMP ratios and MMP activity suggest an imbalance in tear MMP regulation that may explain the predisposition of these patients to demonstrate corneal melting and chronic complications associated with persistent inflammation.	23962653
Tears body substance, Inflammatory abnormality of the eye	Altered Intercellular Communication	Myeloperoxidase in tears may be a sensitive and specific marker for the quantification of ocular inflammation.	23962653
Liver Failure, Inflammation, Malnutrition, Failure (biologic function)	Altered Intercellular Communication	Chronic inflammation, malnutrition, and liver failure causing an impaired healing capacity are important reasons for failure.	23963028
Inflammation, Neck Pain	Altered Intercellular Communication	Non-steroidal anti-inflammatory drugs (NSAIDs) may be used to reduce neck pain and associated inflammation and facilitate earlier recovery.	23964752
Inflammation, hepcidin	Altered Intercellular Communication	Also relations between visfatin and hepcidin, demands for recombinant human erythropoietin (rHuEpo), inflammation, and situations characterized by insulin resistance were evaluated.	23964827
Inflammation, Anemia, Hyperferritinaemia	Altered Intercellular Communication	Seven patients appeared to have anemia of chronic inflammation, and in 5 patients, there was no clearly definable cause for hyperferritinemia.	23965472
Inflammation	Altered Intercellular Communication	In addition, extremely high ferritin levels can be found in patients with seemingly indolent disease or levels of chronic inflammation.	23965472
Adult-Onset Still Disease, Lymphohistiocytosis, Hemophagocytic, Systemic onset juvenile chronic arthritis	Altered Intercellular Communication	A markedly elevated serum ferritin level has been associated with inflammatory conditions such as adult-onset Still's disease, systemic juvenile idiopathic arthritis, and hemophagocytic lymphohistiocytosis/macrophage activation syndrome.	23965472
Inflammation, Subacute Bacterial Endocarditis, Fever, CTCAE	Altered Intercellular Communication	The diagnosis of infectious endocarditis caused by the HACEK group containing C. hominis may become difficult because the fever was not so high and inflammation was not so severe.	23965861
Inflammation, Carcinogenesis	Altered Intercellular Communication	Chronic inflammation may play a role in ovarian carcinogenesis.	23966559
ovarian neoplasm, Inflammation	Altered Intercellular Communication	Our results support the hypothesis that higher levels of circulating CRP are associated with increased risk of ovarian cancer, indicating that the role of inflammation in ovarian cancer requires further elucidation.	23966559
Primary malignant neoplasm, Ulcerative Colitis, Colitis	Altered Intercellular Communication	The aim of this work was to access the expression profile of proteins involved in colonic inflammation and cancer in samples from CD and UC.	23967107
Inflammation, Medically Unexplained Symptoms, Depression, CTCAE, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Only the somatic symptom dimension of depression was associated with CHD, biomarkers (inflammation, vascular function) and cardio-vascular risk factors.	23967272
Somatic, Inflammation, Depression, CTCAE, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Thus, our results partly confirm current models: Somatic, but not cognitive-affective symptom dimensions are responsible for the association between depression and CHD, inflammation, vascular function and cardiovascular risk factors in the general population.	23967272
Inflammation, Coronary Arteriosclerosis, Depression, CTCAE, physiopathological	Altered Intercellular Communication	However, our findings challenge the assumptions that somatic depression might be due to inflammation or vascular dysfunction as consequence of progressed atherosclerotic disease.	23967272
Inflammation, Intimal proliferation	Altered Intercellular Communication	However, the application and use of stent struts induces local and systemic inflammation, leading to intractable neointimal hyperplasia.	23968847
Inflammation, Arteriopathic disease	Altered Intercellular Communication	CD4(+) T cells are involved in artery stenosis diseases, but little is known about the influence of the CD4(+) T cells on the inflammation reaction after stent implantation.	23968847
Inflammation	Altered Intercellular Communication	We speculate that the maintenance of the frequency and function of Tregs controls the inflammatory response, which otherwise induces acute inflammation after stent implantation.	23968847
Chronic lymphocytic inflammation, Clippers	Altered Intercellular Communication	For the first time we describe and interpret Susceptibility Weighted Imaging (SWI) and Perfusion Weighted Imaging (PWI) findings in a case of Chronic Lymphocytic Inflammation with Perivascular Pontine Enhancement Responsive to Steroids (CLIPPERS).	23969198
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The study investigates whether productive activities by older adults reduce bodily inflammation, as indicated by C-reactive protein (CRP), a biomeasure associated with the risk of cardiovascular diseases.	23969258
Inflammation, Hypertension, CTCAE, Cardiovascular Diseases	Altered Intercellular Communication	Productive activities-and frequent volunteering in particular-may protect individuals from inflammation that is associated with increased risk of hypertension and cardiovascular disease.	23969258
Inflammation	Altered Intercellular Communication	The mean methylation level of the FHIT gene was associated with intratumoral inflammation.	23969757
physiopathological	Altered Intercellular Communication	We discuss the multifactorial origin, involving peripheral nerve dysfunction and hormonal dysfunction, as well as psychological traits.	23970045
Drug Eruptions, Communicable Diseases, Inflammation, Neoplasms	Altered Intercellular Communication	The patients were categorized into patients with infection, inflammation, neoplasm and drug-induced fever.	23970321
Inflammation, Neoplasms	Altered Intercellular Communication	The effectiveness of PET-CT and tissue biopsy for diagnosis was considerably high, particularly in the categories of neoplasm and nonspecific inflammation, respectively, though the effectiveness of bacterial culture was low.	23970321
Inflammation	Altered Intercellular Communication	Pyothorax-associated lymphoma (PAL) is a representative form of diffuse large B-cell lymphoma associated with chronic inflammation, in which the Epstein-Barr virus (EBV) genome is consistently detectable in the lymphoma cells of all PAL cases.	23972300
Inflammation, GRN wt Allele	Altered Intercellular Communication	In the in vitro inflammation models, PGRN suppressed both the neutrophil chemotaxis and ICAM-1 expression caused by TNF-a in endothelial cells.	23972823
Inflammation, GRN wt Allele	Altered Intercellular Communication	PGRN exerted ameliorative effects against I/R-induced inflammation, and these effects may be due to the inhibition of neutrophil recruitment into the I/R brain.	23972823
Inflammation	Altered Intercellular Communication	However, it is not clear if lower background exposure to PAHs is associated with inflammation in humans, independent of smoking, a major source of PAHs.	23972896
Degenerative polyarthritis, Pain Distress Question, Inflammation	Altered Intercellular Communication	Knee osteoarthritis (OA) pain is suggested to be associated with inflammation and detrimental mechanical loading across the joint.	23973128
Inflammation, Pain Distress Question	Altered Intercellular Communication	In this cross-sectional study, we simultaneously examined the inflammation and alignment of the lower limb and examined how the pain components varied depending on the disease progression.	23973128
Inflammation, Synovitis	Altered Intercellular Communication	The serum interleukin (sIL)-6 level reflecting synovitis, and the high sensitivity C-reactive protein (hs-CRP) level were measured to evaluate the severity of inflammation.	23973128
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Synovial material from patients with knee OA exhibited different degrees of inflammation.	23973153
Inflammation	Altered Intercellular Communication	Synovial material without inflammation exhibited a similar vascular and neuronal network as the normal knee joint from rat and sheep.	23973153
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Plasma CK-18 raised significantly with any increase in steatosis, inflammation and fibrosis, but there was a significant overlap across disease severity.	23973932
Inflammation, Fibrosis Assessment, Fatty degeneration, Metabolic Syndrome X	Altered Intercellular Communication	CK-18 correlated most strongly with ALT (r=0.57, p<0.0001) and adipose tissue IR (insulin-suppression of FFA: r=-0.43; p<0.001), less with steatosis, lobular inflammation and fibrosis (r=0.28-0.34, all p<0.001), but not with ballooning, BMI, metabolic syndrome or T2DM.	23973932
Inflammation, Lymphohistiocytosis, Hemophagocytic	Altered Intercellular Communication	Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and potentially life-threatening condition characterized by uncontrolled hyper inflammation caused by various inherited or acquired immune deficiencies.	23974460
Inflammatory, Inflammation, Uterine Cervicitis	Altered Intercellular Communication	Among the inflammatory lesions, chronic non-specific cervicitis was the most commonly encountered lesion constituting 72.2% of all inflammation.	23974733
Conjunctivitis	Altered Intercellular Communication	After a few recurrences of mild corneal and conjunctival inflammation, a second conjunctival biopsy was performed at a different site in the same eye, 30 months later.	23974895
Fibrosis Assessment, Conjunctivitis	Altered Intercellular Communication	Despite its rarity in the pediatric age group, MMP should be considered in the differential diagnosis of chronic conjunctival inflammation and fibrosis.	23974895
Inflammation, Macular edema due to diabetes mellitus, Dystonia, Dopa-Responsive, due to Sepiapterin Reductase Deficiency	Altered Intercellular Communication	The significant association of SRD with intravitreal IL-6 indicates that inflammation may play an important role in the development of SRD in diabetic macular edema.	23975003
Inflammation, Dental Plaque, Calcinosis, Vascular calcification	Altered Intercellular Communication	Vascular calcification correlates with inflammation and plaque instability in a dual manner, depending on the spotty/granular (micro) or sheet-like/lamellated (macro) pattern of calcification.	23975852
Inflammation, Calcinosis	Altered Intercellular Communication	Modified lipoproteins trigger both inflammation and calcification via receptors for advanced lipoxidation/glycation endproducts (ALEs/AGEs).	23975852
Osteogenesis, Inflammation	Altered Intercellular Communication	These data indicate a novel molecular mechanism by which galectin-3 and RAGE modulate in divergent ways, not only inflammation, but also vascular osteogenesis, by modulating Wnt/b-catenin signalling, and independently of ALEs/AGEs.	23975852
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Adiponectin has a central role in regulating glucose and lipid metabolism and controlling inflammation in insulin-sensitive tissues and low adiponectin levels have been linked to NAFLD.	23977033
Inflammation, Demyelination, Axonal loss, Demyelinating Diseases	Altered Intercellular Communication	Multiple sclerosis is the most frequent demyelinating disease in the human CNS characterized by inflammation, demyelination, relative axonal loss and gliosis.	23977356
Inflammation, Impaired cognition, glycation	Altered Intercellular Communication	We examined the clinical value of two serum markers of low-grade inflammation, C-reactive protein (CRP) and receptor of advanced glycation products (RAGE), as prognostic indices for cognitive decline.	23978069
Inflammation, Impaired cognition	Altered Intercellular Communication	Chronic low-grade inflammation is present in patients with cognitive impairment.	23978069
Inflammation, Failure (biologic function)	Altered Intercellular Communication	Better patient outcomes are achieved by treating CD at early inflammation stages; delayed treatment increases rates of treatment failure.	23978351
Inflammation, Hepatitis C	Altered Intercellular Communication	HIV and HCV infections contribute to chronic inflammation; however, reduced CRP possibly occurs through HCV-mediated mechanisms.	23978997
Vasculitis, Dental Plaque	Altered Intercellular Communication	Impact of cardiovascular risk factors on vessel wall inflammation and calcified plaque burden differs across vascular beds: a PET-CT study.	23979062
Vasculitis, Dental Plaque	Altered Intercellular Communication	Findings of this PET/CT study demonstrate that the impact of cardiovascular risk factors on vessel wall inflammation and calcified plaque burden differs across vascular territories.	23979062
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Increasing evidence indicates that inflammation contributes to the pathogenesis of atrial fibrillation (AF).	23979265
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	In this study, we investigated whether a local level of PTX3 might be a sensitive marker for the local inflammation of AF.	23979265
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	These data demonstrate that local PTX3 production in the left atrium might reflect the local inflammation of AF.	23979265
Uveomeningoencephalitic Syndrome	Altered Intercellular Communication	The medical records of consecutive patients with Vogt-Koyanagi-Harada disease without active intraocular inflammation were reviewed, and one eye was randomly chosen for analyses.	23979311
Uveomeningoencephalitic Syndrome, Hypopigmentation disorder, Choroiditis	Altered Intercellular Communication	The thinner choroid and larger PPA areas were correlated with the degree of depigmentation or disease duration and might be caused by latent choroidal inflammation in the convalescent stage of Vogt-Koyanagi-Harada disease.	23979311
Inflammation	Altered Intercellular Communication	These precursors would eventually migrate into the lamina propria to differentiate into aT/cB/PC, complying thereby with the immunological mucosal demands generated by the on-going chronic inflammation.	23979405
Mesenteric Panniculitis, Inflammation, Pseudotumor	Altered Intercellular Communication	Mesenteric panniculitis represents a cronic inflammation of the adipose tissue of the mesentery which can present sometimes with the imagistic aspect of one or multiples pseudotumors.	23979623
Inflammation, Obesity	Altered Intercellular Communication	Inflammation is a potential mechanism linking obesity and cardiometabolic risk.	23979951
Inflammation	Altered Intercellular Communication	XBJ was an effective therapeutic drug capable to control the in vivo inflammation reaction in patients with ALI/ARDS.	23980355
Benign Prostatic Hyperplasia, Inflammation	Altered Intercellular Communication	To determine whether low-grade systemic inflammation is associated with prostatic enlargement/benign prostatic hyperplasia.	23980666
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Chronic low-grade systemic inflammation might be involved in the etiology of benign prostatic hyperplasia.	23980666
Gingivitis, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Metabolic syndrome and gingival inflammation in Caucasian children with a family history of obesity.	23980866
Gingivitis, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	To investigate whether metabolic syndrome (MetS) and its components are associated with gingival inflammation in children.	23980866
Inflammation, Tumor necrosis, Gingival Hemorrhage	Altered Intercellular Communication	Gingival inflammation was defined by the level of gingival crevicular fluid (GCF) tumour necrosis factor alpha (TNF-a) and the extent of gingival bleeding.	23980866
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Sex-specific linear regression analyses estimated the associations between MetS and gingival inflammation, adjusting for potential confounders.	23980866
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	An association between MetS and gingival inflammation was observed as early as in childhood, and may differ by sex.	23980866
Inflammation, Spongiosis, Urticaria	Altered Intercellular Communication	Differently, in urticarial lesions, no specific features could be appreciated at confocal analysis beside the presence of signs of spongiosis and perivascular inflammation.	23981107
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	A significant correlation was seen between P53 immunoexpression and histologic grade (P = 0.047), but there was no significant correlation between P53 expression with lymph node metastasis and inflammation intensity.	23981150
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	No significant correlation between GB and P53 immunoexpression, lymph node metastasis, or inflammation intensity was seen.	23981150
Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Acute inflammation	Altered Intercellular Communication	Elevated serum M30-CK18, as an indicator of enhanced apoptosis of hepatocytes, parallels active hepatic inflammation and fibrosis but also biochemical activity in CHC; thus, it may serve as a comprehensive non-invasive marker of disease activity.	23981197
glucagon, human, Inflammation, Pyogenic granuloma, Giant Cell Granuloma	Altered Intercellular Communication	All cases showed microscopic evidence for inflammation; however, although 41% exhibited only nonspecific inflammation, 29.9% exhibited actinomyces-related inflammation, 18.8% pyogenic granuloma (PG), and 10.3% giant cell granuloma (GCG).	23981243
Inflammation	Altered Intercellular Communication	Lesions with simple inflammation could not be distinguished clinically or radiographically from the potentially destructive lesions.	23981243
Inflammation, Actinomycosis	Altered Intercellular Communication	There were no clinical features which could distinguish PI with simple inflammation from potentially destructive lesions mimicking PI, such as GCG, PG, and actinomycosis.	23981243
Inflammation, Actinomycosis	Altered Intercellular Communication	However, to control GCG and PG surgical procedures would be recommended, actinomycosis would indicate specific antibiotics, whereas in nonspecific inflammation, these measures may not be indicated.	23981243
Inflammation, Hypoxia	Altered Intercellular Communication	Pathways related to inflammation, hypoxia, and stress showed activation, and pathways that play roles in neurogenesis and myelination showed decreases.	23981442
Post-Traumatic Stress Disorder, Inflammation, Depression, CTCAE	Altered Intercellular Communication	The cortisol pathway dysregulation and increased inflammation identified here are seen in other stress-related conditions such as depression and post-traumatic stress disorder and most likely play a role in addiction.	23981442
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Correlations of ghrelin serum levels with disease activity, systemic inflammation and metabolic syndrome were assessed.	23981480
Inflammation, Primary malignant neoplasm, Cerebrovascular accident	Altered Intercellular Communication	Chronic inflammation and an activated coagulation system may contribute to the pathogenic mechanism of strokes, the extent of each depending on the activity and severity of cancer.	23981525
ARCN1 gene, Chronic Obstructive Airway Disease, Exacerbation	Altered Intercellular Communication	This increases corticosteroid-resistant airway inflammation in chronic obstructive pulmonary disease (COPD) and leads to exacerbations.	23981542
Airway structure, Bacterial Infections, Exacerbation	Altered Intercellular Communication	We conclude that HASMCs contribute to the increase in airway inflammation in COPD exacerbations caused by gram-positive bacterial infections.	23981542
Cholecystitis	Altered Intercellular Communication	Xanthogranulomatous cholecystitis (XGC) is a rare type of gallbladder inflammation.	23981609
Inflammation, Dental Plaque	Altered Intercellular Communication	The aim of the study was to determine if plaque neovascularization led to inflammation.	23981615
Inflammation	Altered Intercellular Communication	A target to background ratio (TBR) of >= 1.25 or < 1.25 served as the cutoff point for the presence and absence of inflammation, respectively.	23981615
Inflammation	Altered Intercellular Communication	This may be caused by less reduction in coronary circulatory platelet activation and inflammation.	23981616
Hepatic, Nia (fungus), Insemination, Artificial, Homologous, Autoimmune Chronic Hepatitis, Inflammatory, Traumatic injury, Waldenstrom Macroglobulinemia	Altered Intercellular Communication	Autoimmune hepatitis (AIH) after liver transplantation has been defined histologically as a "hepatitic" pattern of injury, characterized by lymphoplasmacytic inflammation with necroinflammatory activity (NIA), comparable with findings seen in native livers.	23982338
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	HIV-infected adults display increased cardiovascular disease, probably driven by inflammation and immune activation.	23982657
Postprandial Period	Altered Intercellular Communication	An Open-Label Randomized Crossover Trial of Lyophilized Black Raspberries on Postprandial Inflammation in Older Overweight Males: A Pilot Study.	23982695
Postprandial Period, Overweight	Altered Intercellular Communication	This study was a 14-day, outpatient, open-label randomized crossover trial of lyophilized black raspberries (BRBs) in older overweight or obese males to determine whether BRB consumption affects postprandial inflammation associated with consumption of a high-fat high-calorie (HFHC) meal.	23982695
Postprandial Period, Overweight	Altered Intercellular Communication	The findings of this pilot study suggest that consumption of lyophilized BRBs may attenuate postprandial inflammation in overweight or obese males consuming a HFHC meal.	23982695
Inflammation, Primary malignant neoplasm, Adenoma of large intestine	Altered Intercellular Communication	Chronic inflammation has been implicated in the etiology of colorectal adenoma and cancer; however, few key inflammatory genes mediating this relationship have been identified.	23982929
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Additional studies on the functional consequences of rs5995355 in NCF4 may help to clarify the mechanistic link between inflammation and colorectal cancer.	23982929
Inflammation, Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis Syndrome, Fever, CTCAE	Altered Intercellular Communication	PFAPA syndrome is characterized by recurrent attacks of fever and symptoms of inflammation consistent with the disease acronym.	23983059
Inflammation, Aggressive behavior, Benign prostatic hypertrophy	Altered Intercellular Communication	We evaluated the correlation between tPSA, fPSa, f/t PSA ratio, cPSA, MPV and extent and aggressiveness of inflammation in the surgical specimens of patients who underwent surgery for benign prostatic hyperplasia (BPH).	23983600
Inflammation, prostatitis	Altered Intercellular Communication	MPV values may be used as an inflammation marker in patients with prostatitis.	23983600
Inflammation, Ovalocytosis, Malaysian-Melanesian-Filipino Type	Altered Intercellular Communication	LAA had a stronger activation of inflammation than SAO in the pathogenesis, which was associated with the changes of CRP.	23983602
Observation Method - Coagulation, Cardiovascular Diseases	Altered Intercellular Communication	Comparison of cardiovascular disease risk markers in HIV-infected patients receiving abacavir and tenofovir: the nucleoside inflammation, coagulation and endothelial function (NICE) study.	23985706
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Among individuals assigned to ABC or TDF in randomized clinical trials there were no significant differences in FMD or markers of inflammation and coagulation.	23985706
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Whether ABC contributes to risk of CVD remains unclear, but our results suggest that endothelial dysfunction, heightened inflammation, and altered coagulation are unlikely to be mechanisms by which the drug could increase CVD risk above that seen with TDF.	23985706
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Chronic inflammation has been implicated in the pathogenesis of colorectal cancer.	23985781
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Tuberculosis, Diabetes Mellitus	Altered Intercellular Communication	Our data reveal that tuberculosis with diabetes is characterized by heightened cytokine responsiveness, indicating that chronic inflammation underlying type 2 diabetes potentially contributes to increased immune pathology and poor control in tuberculosis infection.	23987505
Inflammation, Intracranial Hypertension, Hydrocephalus, Meningitis	Altered Intercellular Communication	Cryptococcal choroid plexus inflammation is a particularly rare entity most often presenting with signs and symptoms of intracranial hypertension, hydrocephalus or meningitis due to a delayed diagnosis.	23988229
Inflammation, Congestive heart failure	Altered Intercellular Communication	Severe CSA in CHF patients is associated with elevated levels of CRP, a systemic marker of inflammation and cardiovascular risk.	23988380
Inflammation	Altered Intercellular Communication	Chronic, low grade inflammation is a characteristic of old age.	23988651
Inflammation	Altered Intercellular Communication	In summary, our data suggests that LiCl reduces inflammation in aged and young DCs via different mechanisms.	23988651
Sepsis, Inflammation, physiopathological, Hypoperfusion	Altered Intercellular Communication	Glycocalyx degradation may contribute to microvascular dysfunction and tissue hypoperfusion during systemic inflammation and sepsis.	23988876
Inflammation, Sensorineural Hearing Loss (disorder)	Altered Intercellular Communication	Recently, the cause of ISSNHL, which is still unclear, has been focused on chronic inflammation.	23988996
Airway structure	Altered Intercellular Communication	Determining the site of airways inflammation may lead to the targeting of therapy.	23989961
Refractory anemias	Altered Intercellular Communication	RA is associated with dysregulation of T-cell subsets (naive, regulatory (Treg) and inflammation-related cells (IRC)) early in the disease.	23989988
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Higher religion scores were associated with lower levels of inflammation in advanced cancer patients still undergoing ANTs.	23990104
Sepsis	Altered Intercellular Communication	Immune activation is a regular feature of sepsis, but the incidence and nature of the ensuing inflammation-resolving and immunosuppressive component is less well understood.	23990136
Ischemic stroke	Altered Intercellular Communication	Inflammation-induced catabolism of tryptophan and tyrosine in acute ischemic stroke.	23990339
Adrenocortical, Neoplasm, uncertain whether benign or malignant	Altered Intercellular Communication	Adrenocortical oncocytoma of borderline malignant potential with high FDG uptake may require long-term follow-up with clinical, hormonal, and imaging evaluations.	23990396
Infection caused by Onchocerca, Inflammation	Altered Intercellular Communication	All of the previously reported cases of O. lupi in both humans and dogs were more symptomatic than in our patient, Onchocerca infection should not be ruled out during the differential diagnosis of the subconjunctival and orbital cystic mass in instances where there is little to no inflammation.	23990437
Chronic kidney disease stage 5, Communicable Diseases, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Although procalcitonin (PCT) has been described as a marker of infection and inflammation, it has not been extensively studied in patients with chronic kidney disease (CKD), end stage renal disease, or renal transplant.	23990496
Inflammation, PLAU protein, human	Altered Intercellular Communication	Urokinase-type plasminogen activator receptor is a multifunctional glycoprotein, the expression of which is increased during inflammation.	23990945
Chronic lymphocytic inflammation, Lupus Erythematosus	Altered Intercellular Communication	Typical histologic features of cutaneous lupus, such as follicular plugging, angiocentric lymphocytic inflammation, and dermal mucin, are very helpful clues to the diagnosis of hypertrophic lupus erythematosus.	23991731
Inflammation, Observation Method - Coagulation, Traumatic injury	Altered Intercellular Communication	A2AP deficiency further was associated with exaggerated systemic inflammation and coagulation, increased distant organ injury, and enhanced lethality.	23992406
Periarticular Route of Administration	Altered Intercellular Communication	Imaging revealed articular or periarticular inflammation in many cases and bone lesions near 22% of affected joints.	23992800
Inflammation, Atherosclerosis of aorta	Altered Intercellular Communication	The present work favors a role for coinfection of both M pneumoniae and C pneumoniae in the development of aortic atherosclerotic aneurysm, with increased adventitial inflammation, inhibition of TIMP-1 activity, and increased collagen degradation.	23993112
Peripheral ulcerative keratitis, Inflammation	Altered Intercellular Communication	Peripheral ulcerative keratitis (PUK) is a sight-threatening condition characterized by an epithelial defect, crescent-shaped stromal inflammation, and progressive stromal thinning.	23993305
Sarcoidosis	Altered Intercellular Communication	We describe a case report of PUK associated with the inflammatory condition of sarcoidosis.	23993305
Hepatitis, Communicable Diseases, Keratitis, Syphilis, Fungal keratitis, Keratitis, Herpetic, "Moorens ulcer	Altered Intercellular Communication	PUK can also be associated with infectious and inflammatory conditions such as hepatitis, syphilis, herpes simplex keratitis, fungal keratitis, Mooren ulcer, and marginal keratitis.	23993305
Inflammation, Neuropathologist, "Alzheimers Disease", Tumor necrosis, senile	Altered Intercellular Communication	Alzheimer's disease is neuropathologically characterized by the accumulation of amyloid-b protein into senile plaques that are sites of chronic inflammation involving reactive microglia, astrocytes, and proinflammatory molecules, such as interleukin-1b and tumor necrosis factor-a.	23993701
Inflammatory disorder	Altered Intercellular Communication	The human CCAAT/enhancer-binding protein (CEBP) delta (CEBPD) is known to be induced in many inflammation-related diseases.	23993701
Inflammation, Osteolysis	Altered Intercellular Communication	We aimed to characterize the unknown pathophysiological effects of APN on wear particle-induced inflammation, apoptosis and osteolysis.	23994269
Inflammation, Osteolysis	Altered Intercellular Communication	Osteolysis and inflammation were quantified by histomorphometry and microcomputed tomography, apoptosis by immunohistochemistry and TUNEL assay.	23994269
Osteolysis	Altered Intercellular Communication	Administration of APN in mice significantly reduced wear particle-induced inflammation, osteolysis and the number of caspase-3-positive macrophages.	23994269
Communicable Diseases, Inflammation	Altered Intercellular Communication	Infection was the most common cause of LR (n = 83, 47.9%; 95% confidence interval, 40.7-55.4), followed by ischemia/stress (27.7%), inflammation (6.9%), and obstetric diagnoses (6.9%).	23994818
Inflammation, Infection	Altered Intercellular Communication	LR was found to have multiple etiologies including infections, stress, inflammation, and obstetric diagnoses.	23994818
Infection caused by Helicobacter pylori, Malignant neoplasm of gastrointestinal tract, Chronic gastritis	Altered Intercellular Communication	Epidemiological investigations indicated association of the Helicobacter pylori infections with the occurrence of inflammatory conditions of the gastric mucosa and development of chronic gastritis and intestinal type of gastric cancer.	23995914
Hypertensive disease, Inflammation, Refractory anemias	Altered Intercellular Communication	We examined the hypothesis that mediators of inflammation and markers of cardiovascular risk are associated with HTN in RA.	23996293
Hypertensive disease, Inflammation, Refractory anemias	Altered Intercellular Communication	HTN in patients with RA is not associated with generalized systemic inflammation or insulin resistance, but is associated with increasing concentrations of homocysteine and leptin.	23996293
allergic inflammation, Chronic sinusitis	Altered Intercellular Communication	It seemed that aspirin had positive effects in allergic inflammation at least in some subset of aspirin tolerant patients with chronic sinusitis.	23996718
Pneumonia, Lipid, Pneumonitis	Altered Intercellular Communication	Lipoid pneumonia (LP) is a chronic inflammation of the lung parenchyma with interstitial involvement due to the accumulation of endogenous or exogenous lipids.	23996884
Airway structure	Altered Intercellular Communication	Fractional exhaled nitric oxide (FeNO) measurement is an important noninvasive tool for evaluating eosinophilic inflammation of the airways.	23998240
Damage	Altered Intercellular Communication	Human mesenchymal stem/stromal cells (hMSCs) have been reported to improve neural damage via anti-inflammation and multi-differentiation abilities.	23998421
Pain Distress Question, Varicose Ulcer, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Patients with venous leg ulcers experience multiple symptoms, including pain, depression, and discomfort from lower leg inflammation and wound exudate.	23998779
Pain Distress Question, Inflammation, Dyssomnias, Exudate, Swelling, Depression, CTCAE, Fatigue	Altered Intercellular Communication	Exploratory factor analysis identified two symptom clusters: pain, depression, sleep disturbance, and fatigue; and swelling, inflammation, exudate, and fatigue.	23998779
Airway structure	Altered Intercellular Communication	Given previous evidence that exhaled isoprene is elevated in systemic inflammatory states, we hypothesized that exhaled isoprene would be positively associated with a breath biomarker of airway inflammation, the fractional concentration of exhaled nitric oxide (FENO).	23999846
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver biopsy showed patchy advanced fibrosis, mild inflammation, positive staining for copper, and a tissue copper concentration of 768 ug/g (10-35 mg/g).	23999958
Inflammation, Intradermal Route of Drug Administration	Altered Intercellular Communication	In adult CF patients iron deficiency (ID) is common and primarily functional due to chronic inflammation.	24000193
Inflammation, Lung diseases	Altered Intercellular Communication	Over the last decades onset of inflammation and pulmonary disease in children with CF is delayed by improved nutritional status.	24000193
Inflammation	Altered Intercellular Communication	Higher Fer values found in older children represent an increased state of inflammation, rather than an improved iron status, and might increase the relative contribution of functional ID.	24000193
Inflammation, Muscle Strength, Hyperuricemia	Altered Intercellular Communication	However, several studies have demonstrated that hyperuricemia is closely related to systemic inflammation and has oxidant properties effects, both of which may increase the risk of muscle strength loss.	24000893
Inflammation, LATS1 gene, Traumatic injury	Altered Intercellular Communication	The external examination revealed multiple warts in the perianal region, but no lesions, discharge, inflammation, or external signs of trauma were visible.	24001431
Inflammation, Tuberculous osteomyelitis	Altered Intercellular Communication	A 71-yr-old man presented with inflammation in the left elbow and he underwent a surgery under the suspicion of tuberculous osteomyelitis.	24003427
Inflammation, Arteriosclerosis, Autoimmune Diseases, Infection, Connective Tissue, Colagenosis, Disease	Altered Intercellular Communication	netic factors, infections, disorders in connective tissue (collagenosis), arteriosclerosis, inflammation, incorrect immune response (autoimmunity).	24003660
Inflammation, Blood Clot, Dental Plaque, Angina Pectoris	Altered Intercellular Communication	In conclusion, culprit lesions in STEMI patients showed a greater plaque burden, remodeling index, and more frequent thrombi with increased inflammation and neovascularization compared to the stable angina group, supporting the current concept of vulnerable plaques being responsible for STEMI.	24005982
Inflammation, Hyperplasia, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	Vascularization was combined in all eyes with SCC, in two of eight (25%) with CIN, in two of three with inflammation, and in none with hyperplasia.	24006080
Inflammation, Hyperplasia, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	Both cornea and conjunctiva were involved in ten of 11 eyes (90.9%) with SCC, in six of eight (75%) with CIN, in two of eight (25%) with hyperplasia, and in two of three (66.7%) with inflammation.	24006080
Inflammation, Hyperplasia	Altered Intercellular Communication	Hyperplasia or lesions with inflammation did not recur.	24006080
Hepatic inflammation, FAM126A gene	Altered Intercellular Communication	We hypothesized that long-term iron deficiency could attenuate the hepatic inflammation and lead to a lower incidence of HCC in India than expected.	24006121
Inflammation, Peripheral Arterial Diseases	Altered Intercellular Communication	Impaired vascular endothelial growth factor A and inflammation in patients with peripheral artery disease.	24006146
Inflammation, Peripheral Arterial Diseases, GDC Comorbidity Terminology	Altered Intercellular Communication	We compared apoptosis, cellular oxidative stress, and inflammation of cultured endothelial cells treated with sera from 130 patients with peripheral artery disease (PAD) and a control group of 36 patients with high burden of comorbid conditions and cardiovascular risk factors.	24006146
Additional	Altered Intercellular Communication	Additional alterations in phosphoproteins suggests dysregulation of mitochondria, synaptic transmission, vesicle trafficking, and innate immune pathways.	24006891
Inflammation, Muscle of orbit	Altered Intercellular Communication	Eyes with a clinical VISA inflammation score of <= 4 had an average extraocular muscle SUVmax of 3.09, and those with a score of >= 5 had an average SUVmax of 3.92 (P = 0.09), showing no clear correlation between clinically observed inflammation and 18-FDG uptake.	24007404
Inflammation, Muscle of orbit	Altered Intercellular Communication	We demonstrated a lack of correlation between 18-FDG extraocular muscle uptake and either clinical inflammation score or muscle diameter.	24007404
Uveitis	Altered Intercellular Communication	Incidence and prevalence of uveitis: results from the Pacific Ocular Inflammation Study.	24008391
Malnutrition	Altered Intercellular Communication	The time-averaged serum bacterial DNA level significantly correlated with malnutrition inflammation score (r = 0.550, p = 0.008) and inversely with subjective global assessment score (r = -0.543, p = 0.009), but not with PWV.	24008429
Inflammation, Vascular Stiffness	Altered Intercellular Communication	In hemodialysis patients, circulating endotoxin level is associated with vascular stiffness and systemic inflammation.	24008429
Inflammation	Altered Intercellular Communication	We suggest the use of this ratio for the assessment of aortic inflammation in GCA patients.	24008434
Inflammation, Hydronephrosis, Adenocarcinoma, Urolithiasis, Intestinal metaplasia	Altered Intercellular Communication	Although their pathogenesis is not well defined, adenocarcinomas are likely to originate from neoplastic transformation of the glandular cells of the urothelial intestinal metaplasia usually arising in response to chronic irritating stimuli, such as long-duration inflammation, urolithiasis, and hydronephrosis.	24008439
Tubulovillous adenoma, Primary malignant neoplasm, Inflammation, Adenocarcinoma, Adenoma, Villous, Intestinal metaplasia	Altered Intercellular Communication	Histological examination disclosed an infiltrating adenocarcinoma arising from a tubulovillous adenoma with the surrounding pelvic mucosa showing a sequence of intestinal metaplasia, low- and high-grade villous adenoma, and invasive adenocarcinoma, supporting the hypothesis of cancer progression due to chronic inflammation from the urothelium through the metaplasia step.	24008439
Inflammation, Infection caused by Helicobacter pylori, Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	Chronic inflammation, such as Helicobacter pylori infection, is considered to be a cause of MALT lymphoma.	24008643
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	We analysed the densities of eight types of inflammatory cells in a prospectively recruited group of 117 CRC patients and determined their interrelationships and contributions to Klintrup-Makinen (K-M) score of overall peritumoural inflammation.	24008661
Inflammation, Kidney Failure	Altered Intercellular Communication	Systemic inflammation, as evidenced by elevated inflammatory cytokines, is a feature of advanced renal failure and predicts worse survival.	24009237
Inflammation, Comorbidity	Altered Intercellular Communication	After adjustment for multiple covariates, systemic inflammation was associated with age and comorbidity and independently predicted patient survival in both incident and prevalent cohorts.	24009237
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Few studies have examined the changes in lipoproteins over time and how inflammation is associated with lipoprotein concentrations among patients with end-stage renal disease on dialysis.	24009290
Inflammation	Altered Intercellular Communication	Changes in inflammatory markers were associated with changes in apo A1, but not apo B over 1 year, suggesting that reductions in high-density lipoprotein cholesterol are associated with inflammation, either of which could mediate cardiovascular risk, but not supporting a hypothesis linking increased risk of low levels of apo B containing lipoproteins to the risk associated with inflammation.	24009290
Inflammation, Polyneuropathy	Altered Intercellular Communication	Association of subclinical inflammation with polyneuropathy in the older population: KORA F4 study.	24009302
Adrenal incidentaloma	Altered Intercellular Communication	Based on these findings, initial hormonal and radiographic evaluations for adrenal incidentalomas appear to be more important than follow-up tests because functional or malignant changes are rare.	24009451
Inflammation, SLC25A20 gene, Atherosclerosis	Altered Intercellular Communication	These results demonstrate that the degree of chronic adaptive immune activation is associated with both CAC and CC IMT in otherwise healthy individuals, consistent with the known role of CD4(+) T cells, and with innate immunity (inflammation), in atherosclerosis.	24009662
Inflammation, Atherosclerosis, Arteritis	Altered Intercellular Communication	As atherosclerosis is a disease characterized by chronic arterial inflammation, it is possible that moderate increases in CRP level reflect the presence of plaque inflammation.	24010553
Inflammation, Dental Plaque	Altered Intercellular Communication	To investigate this possibility, we compared plasma levels of hsCRP the day before carotid endarterectomy with the degree of inflammation in the excised plaque tissue.	24010553
Inflammation	Altered Intercellular Communication	The present findings strongly argue against hsCRP as a marker of plaque inflammation.	24010553
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Hence, it is more likely that elevated hsCRP is a sign of a subclinical systemic inflammation and this in turn may contribute to progression of cardiovascular disease.	24010553
Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Chronic Kidney Diseases	Altered Intercellular Communication	We investigated the relationships between dietary fat quality, the metabolic syndrome (MetS), insulin sensitivity and inflammation in individuals with CKD.	24011327
Inflammation, ETV3 wt Allele, Chronic Kidney Diseases	Altered Intercellular Communication	A serum fatty acid pattern reflecting low LA and high SFA was strongly associated with MetS, IR and inflammation in two independent surveys of elderly individuals with CKD.	24011327
Inflammation, Acne	Altered Intercellular Communication	Acne is a common disorder of the human pilosebaceous unit, yet the mechanisms underlying hyperkeratinisation and subsequent inflammation (comedogenesis) remain to be determined, although cutaneous pathogens are implicated.	24011352
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Chronic Kidney Diseases	Altered Intercellular Communication	Association of biomarkers of inflammation and oxidative stress with the risk of chronic kidney disease in Type 2 diabetes mellitus in North Indian population.	24012111
Inflammation, Damage, diabetic	Altered Intercellular Communication	increased MDA and decreased GSH and FRAP in DM-CKD suggest an important role of inflammation and oxidative stress in the pathogenesis of renal damage in diabetic patients.	24012111
Inflammation, Cachexia	Altered Intercellular Communication	Cancer cachexia is associated with impaired nutritional status and systemic inflammation.	24012284
Malignant neoplasm of esophagus, Inflammation	Altered Intercellular Communication	Impaired nutrition status, elevated energy expenditure, and higher inflammation status tend to be apparent in weight-losing patients with newly diagnosed esophageal cancer, which suggested that early recognition of body weight change and routine nutritional risk screening followed by adequate nutrition intervention should be applied in these patients.	24012284
Kit Ligand, human	Altered Intercellular Communication	Although within the normal range, the increased numbers of WBCs and neutrophils in patients with SCF suggest that SCF may be a subclinical inflammatory condition.	24012331
Neoplasms	Altered Intercellular Communication	Recruitment of immune cells to tumors is a complex process crucial for both inflammation-driven tumor progression and specific anti-tumor cytotoxicity.	24013383
Communicable Diseases, Inflammation, Neoplasms	Altered Intercellular Communication	The accuracy of CT-guided CNB for specific diagnosis of benign soft-tissue tumours as well as infection and inflammation was relatively low.	24014785
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Chronic inflammation is thought to be the leading cause of colorectal cancer, and interleukin-10 (IL10) has been identified as a potent immunomodulatory cytokine that regulates inflammatory responses in the gastrointestinal tract.	24015034
Inflammation, Diabetes Mellitus, Cardiovascular Diseases	Altered Intercellular Communication	Chemical modification of apoA-I, as may occur under conditions of inflammation or diabetes, can severely impair HDL function and is associated with the presence of cardiovascular disease.	24015188
Necrotizing granulomatous inflammation, Hemorrhage	Altered Intercellular Communication	A second biopsy revealed chronic granulomatous dermal inflammation and hemorrhage with foreign body giant cells non-infectious by stains.	24015784
HSPG2 wt Allele, Inflammation, Necrosis	Altered Intercellular Communication	SJS is a rare and acute, self-limited disease, characterized by severe inflammation and necrosis of two or more mucous membranes.	24016288
Inflammation, Vascular Invasion Assessment, FAM126A gene	Altered Intercellular Communication	We suggest that inflammation of hepatic microenvironment promote pathological degradation and microvascular invasion of HCC.	24018067
Inflammation, Demyelination, Experimental Autoimmune Encephalomyelitis, Nerve Degeneration	Altered Intercellular Communication	ASCs from older donors failed to ameliorate the neurodegeneration associated with EAE, and mice treated with older donor cells had increased central nervous system inflammation, demyelination, and splenocyte proliferation in vitro compared with the mice receiving cells from younger donors.	24018793
Inflammation	Altered Intercellular Communication	Laboratory investigations revealed an inflammation with increased C-reactive protein, elevated erythrocyte sedimentation rate and neutrophil count.	24021028
Inflammatory abnormality of the eye	Altered Intercellular Communication	The primary efficacy end point was cleared ocular inflammation, as measured by the summed ocular inflammation score of zero (anterior chamber cell count = 0 and absence of flare) by day 15.	24021896
Pain Distress Question, Inflammatory abnormality of the eye	Altered Intercellular Communication	Secondary end points included cleared ocular inflammation at day 15 and the number of subjects who were pain free at day 1.	24021896
Inflammatory abnormality of the eye	Altered Intercellular Communication	A significantly higher proportion of subjects treated with bromfenac 0.07% achieved complete clearance of ocular inflammation by day 15 and at day 15 compared with placebo (P < 0.0001).	24021896
Cataract, Pain Distress Question, Inflammatory abnormality of the eye	Altered Intercellular Communication	Bromfenac ophthalmic solution 0.07% dosed once daily was clinically safe and effective compared with placebo for the treatment of ocular inflammation and pain in subjects who had undergone cataract surgery and may be a beneficial addition to the current standard of care, which commonly includes ophthalmic antibiotics and corticosteroids.	24021896
Inflammation, Macular Edema, Cystoid, Papilledema, Periphlebitis	Altered Intercellular Communication	Examination revealed mild anterior chamber inflammation, optic disc swelling, cystoid macular edema and periphlebitis in both eyes.	24022644
Tinnitus, Sensorineural Hearing Loss (disorder), Headache, Inflammatory abnormality of the eye	Altered Intercellular Communication	About 6 months after subsequent treatment with an oral corticosteroid started, headache, tinnitus, and sensorineural hearing loss developed, and increased choroidal thickness was observed without other evidence of increased ocular inflammation.	24022645
Inflammation, Fibrosis Assessment, Edema	Altered Intercellular Communication	Endoscopic resection (ER) causes inflammation, edema, fibrosis of the stomach, and severe adhesions around the surrounding tissue.	24023345
Inflammation, Ischemic stroke	Altered Intercellular Communication	Inflammation exists in inception, progression, and reperfusion of acute ischemic stroke.	24023414
Inflammation, Fever, CTCAE, Epithelial, Acute Lung Injury, Endothelial dysfunction	Altered Intercellular Communication	Acute lung injury (ALI) is characterized by inflammation, leukocyte activation, neutrophil recruitment, endothelial dysfunction, and epithelial injury, which are all affected by fever.	24024608
Fat-Free Diet, vascular inflammations	Altered Intercellular Communication	In summary, TRP in fat-free milk may provide cardiovascular benefits beyond that of fPS by inducing more substantial decreases in LDL cholesterol and particle concentration, associated with declines in markers of vascular inflammation.	24024768
Sepsis, Inflammation	Altered Intercellular Communication	Systemic endotoxin activity correlates with clot formation: an observational study in patients with early systemic inflammation and sepsis.	24025340
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Inflammation and coagulation are closely linked, and both can be triggered by endotoxin.	24025340
Pain Distress Question, Inflammation, Sleep-Disordered Breathing, Sleep Fragmentation, Hypoxemia	Altered Intercellular Communication	On the basis of experimental and clinical evidence, the authors hypothesized that nocturnal hypoxemia would be associated with pain reports in subjects suffering from sleep-disordered breathing, independently of sleep fragmentation and inflammation.	24025612
Pain Distress Question, Sleep Fragmentation, Inflammation, Sleep-Disordered Breathing	Altered Intercellular Communication	Nocturnal arterial desaturation may be associated with an increased pain in subjects with sleep-disordered breathing, independently of sleep fragmentation and inflammation.	24025612
Inflammation	Altered Intercellular Communication	Ontology and pathway analyses showed inflammation as the principal biological function associated with these miRNAs.	24025639
Glomerulitis (disorder), Interstitial inflammation, Tubulitis Assessment, Infiltration, Intimal Arteritis Assessment	Altered Intercellular Communication	Pathological findings favoring AMR (PTC infiltration and glomerulitis) showed a greater risk of DSC compared with those favoring CMR (interstitial inflammation, intimal arteritis, and tubulitis).	24025693
Inflammation, Discitis	Altered Intercellular Communication	18F-FDG-PET is therefore an important tool in inflammation imaging and can be used in the diagnostic cascade of difficult cases with suspected spondylodiscitis.	24025917
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	This study shows that chronic inflammation plays a role in impaired HRQL in patients with cirrhosis irrespective of minimal HE.	24025977
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Diabetes damages major organ systems through disrupted glycemic control and increased inflammation.	24026562
Inflammation, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	Neutrophil-to-lymphocyte ratio (NLR), an inflammation index, is considered a prognostic predictor of hepatocellular carcinoma (HCC).	24026659
Inflammation, Neoplasms	Altered Intercellular Communication	STAT3 in epithelial cells regulates inflammation and tumor progression to malignant state in colon.	24027425
Inflammation, Neoplasms, Colorectal Carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Chronic inflammation is an important risk factor for the development of colorectal cancer; however, the mechanism of tumorigenesis especially tumor progression to malignancy in the inflamed colon is still unclear.	24027425
Neoplasms	Altered Intercellular Communication	Our data suggest that epithelial STAT3 plays a critical role in inflammation-induced tumor progression through regulation of leukocytic recruitment especially the infiltration of Treg cells in the large intestine.	24027425
Inflammation, Structure of achilles tendon, Abnormal degeneration	Altered Intercellular Communication	In the radiological study, 27 of the 52 MRI showed signs of Achilles tendon inflammation and/or degeneration, and the PF was 3.43 +- 0.48 mm thick (99%CI and SD = 0.95), as opposed to 2.09 +- 0.24 mm (99%CI, SD = 0.47) in the patients in which the MRI revealed no Achilles tendon diseases; this difference in thickness of 1.29 +- 0.57 mm (99%CI) was statistically significant (P < 0.001).	24028383
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Does decreased mean platelet volume predict inflammation in chronic renal failure, dialysis, and transplanted patients?	24028675
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Blood-based anti-amyloid-b (Ab) immunoglobulins (IgGs) and peripheral inflammation are factors correlating with development of Alzheimer's disease (AD).	24028868
Inflammation, Data types - Address	Altered Intercellular Communication	The differences observed between genders prior to the onset of AD may indicate a lower ability in females to suppress peripheral inflammation, which may lead to exacerbated disease progression.	24028868
Myelitis, Paraplegia, Illness (finding)	Altered Intercellular Communication	We describe a case of severe brainstem and spinal cord inflammation with paraplegia and sphincter involvement in a 48 year old woman following recovery from a Pf malarial illness.	24029237
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Vascular risk factors, and markers of inflammation and endothelial dysfunction predicted lower performance in several cognitive domains.	24029412
Inflammation, Impaired cognition, Endothelial dysfunction	Altered Intercellular Communication	These findings suggest that inflammation and endothelial dysfunction might play a role in the predementia cognitive impairment stages.	24029412
Histoplasmosis	Altered Intercellular Communication	Organ transplantation and increasing use of immunosuppressive agents for chronic inflammatory conditions in non-HIV patients now account for most of the cases of histoplasmosis.	24029651
Inflammation, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	We observed no evidence that obesity contributed to a decline in IQ, even among obese individuals who displayed evidence of the metabolic syndrome and/or elevated systemic inflammation.	24029684
Pituitary Neoplasms, Cerebrovascular accident	Altered Intercellular Communication	The hormonal and imaging data suggested that silent apoplexy of pituitary tumor led to spontaneous remission of CS.	24030190
Inflammation, Cardiac complication	Altered Intercellular Communication	Excess visceral fat is associated with chronic systemic inflammation and cardiovascular complications.	24030946
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	CXCL12 and its unique receptor CXCR4, play important roles in inflammation and cancer metastasis.	24032722
HMGCL gene, Inflammation, Hodgkin Disease, Lymphatic Vessel Tumors	Altered Intercellular Communication	Hodgkin lymphoma (HL) is a rare neoplasm of the lymphatic system, in which inflammation and allelic variants in cytokines have been proposed as etiological factors.	24033107
Airway structure, Inflammation, Exacerbation, myocardial injury	Altered Intercellular Communication	To investigate how COPD exacerbations and exacerbation frequency impact cardiovascular risk and myocardial injury, and whether this is related to airway infection and inflammation.	24033321
Arterial Stiffness, Inflammation	Altered Intercellular Communication	Increases in arterial stiffness are related to inflammation, and are slow to recover.	24033321
Perifolliculitis	Altered Intercellular Communication	The overall prevalence of trachomatous inflammation-follicular (TF) in children aged 1-9 years was 3.8% (95% CI 2.5-5.6), and the overall prevalence of trichiasis in adults aged >=15 years was 0.46% (95% CI 0.17-1.14).	24033501
Inflammation	Altered Intercellular Communication	Serum Helicobacter pylori CagA antibody titer as a useful marker for advanced inflammation in the stomach in Japan.	24033876
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Serum CagA antibody titer was also significantly correlated with mucosal inflammation in the corpus (P = 0.04).	24033876
Airway structure, Lung diseases	Altered Intercellular Communication	Exhaled nitric oxide (NO) is a noninvasive biomarker of airway inflammation in pulmonary diseases.	24033943
Airway structure, ARCN1 gene	Altered Intercellular Communication	The role of exhaled H2S in airway inflammation in COPD still needs further investigation.	24033943
Inflammation, Dental Plaque	Altered Intercellular Communication	Furthermore, at sites with similar amounts of plaque, less clinical signs of gingival inflammation were observed in the Magnolia group than in the control group.	24034670
Malignant neoplasm of urinary bladder, Inflammation, Neoplasms	Altered Intercellular Communication	Treatment of muscle-invasive bladder cancer with chemotherapy results in haemorrhagic inflammation, mimicking residual tumour on conventional MR images and making interpretation difficult.	24034835
Spinal rigidity, Arthritis, Inflammation, Spondylitis	Altered Intercellular Communication	Ankylosing spondylitis is a chronic immune-mediated inflammatory disease characterised by spinal inflammation, progressive spinal rigidity, and peripheral arthritis.	24035250
Inflammation, Sarcoidosis, Carcinoma of lung	Altered Intercellular Communication	Of 59 eligible patients, 41 patients had TB, 5 had lung cancer, 7 had inflammation, and 6 had sarcoidosis.	24035300
Inflammation	Altered Intercellular Communication	The MAR was independently and significantly inversely associated with CRP, suggesting diet is associated with the regulation of inflammation.	24035460
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	The association between smoking quantity and hypertension mediated by inflammation in Chinese current smokers.	24036901
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Previous studies indicated that cigarette smokers were more likely to develop hypertension, and both smoking and hypertension were associated with inflammation.	24036901
Inflammation	Altered Intercellular Communication	SIRT1 negatively regulates amyloid-beta-induced inflammation via the NF-kB pathway.	24036938
methyldopa, Inflammation	Altered Intercellular Communication	Chronic inflammation induced by amyloid-beta (Ab) plays a key role in the development of age-related macular degeneration (AMD), and matrix metalloproteinase-9 (MMP-9), interleukin (IL)-6, and IL-8 may be associated with chronic inflammation in AMD.	24036938
Retinal Degeneration, Inflammation, methyldopa	Altered Intercellular Communication	Our findings suggest a protective role for SIRT1 signaling in Ab-dependent retinal degeneration and inflammation in AMD.	24036938
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	These were compared with location-matched histopathological grading of inflammation (AIS) and fibrosis (FS) using Spearman correlation, Kruskal-Wallis and Chi-squared tests.	24037299
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	* Several MRI parameters correlate with inflammation and fibrosis scores from histopathology.	24037299
Structure of posterior cerebral artery, Infection, Sexually Transmitted Diseases, prostatitis	Altered Intercellular Communication	Number of sexual partners and a history of sexually transmitted infections (STIs) have been positively associated with PCa risk, and these associations may be related to pathogen-induced chronic prostatic inflammation.	24037734
prostatitis, Structure of posterior cerebral artery	Altered Intercellular Communication	These findings support a hypothesized biological mechanism whereby prostatic infection/inflammation may enhance risk of PCa.	24037734
Inflammation, Myositis	Altered Intercellular Communication	Seventy percent were inflammatory myopathies, and 2 had focal inflammation in the muscle.	24037820
Inflammation, Psoriasis, Myopathy	Altered Intercellular Communication	Myopathy or inflammation in muscle affects an average of 1.32 of every 1000 psoriasis patients.	24037820
Hypoglycemia, Neurotransmitters	Altered Intercellular Communication	OBJECTIVE/CONTEXT: Long-fasting hypoglycemia in children may be induced by neurotransmitter disorders.	24037885
Hypoglycemia, Neurotransmitters	Altered Intercellular Communication	Thus, neurotransmitter disorders should be considered in any patients presenting hypoglycemia with urine excretion of vanillactic acid.	24037885
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Liver biopsies from 63 C282Y homozygous patients were assessed for hepatic iron concentration (HIC) and graded for iron loading, fibrosis stage, steatosis, and inflammation.	24037895
Inflammation, MDFIC gene, GDC Disease Response Terminology	Altered Intercellular Communication	HIC, age, hepatocyte senescence and proliferation, portal inflammation, and excessive alcohol consumption all had significant associations with the extent of the DR.	24037895
Inflammation, GDC Disease Response Terminology, Fibrosis Assessment, replication fork arrest, Portal inflammation	Altered Intercellular Communication	In multivariate analysis, iron loading, hepatocyte replicative arrest, and portal inflammation remained independently and significantly associated with the DR. Of factors associated with fibrosis progression, the DR (odds ratio [OR] 10.86 P<0.0001) and the presence of portal inflammation (OR 4.31, P=0.028) remained significant after adjustment for cofactors.	24037895
Inflammation, Hemochromatosis, Fibrosis Assessment, GDC Disease Response Terminology	Altered Intercellular Communication	Portal inflammation occurs in hemochromatosis and is independently associated with the DR and fibrosis, and thus its role in this disease should be evaluated further.	24037895
Inflammation, Hemorrhage, Necrosis, Liver damage, Cholestasis	Altered Intercellular Communication	Liver histology from 128 patients presenting with hepatocellular injury had more severe inflammation, necrosis, and apoptosis and more frequently demonstrated lobular disarray, rosette formation, and hemorrhage than those with cholestasis.	24037963
Inflammation, Edema	Altered Intercellular Communication	In these discrepant cases, lung sections showed significant inflammation and edema, likely accounting for increased wet lung weight.	24039222
Inflammation	Altered Intercellular Communication	To compare the mucosal concentrations of 5-aminosalicylic acid (5-ASA) resulting from different pharmaceutical formulations and analyse the influence of inflammation on the mucosal concentrations.	24039359
Inflammation	Altered Intercellular Communication	Similar results were obtained when we compared patients with the histological appearance of remission and patients with active histological inflammation (67.53 +- 9.22 ng/mg vs 35.53 +- 5.63 ng/mg, P < 0.001).	24039359
Dual-affinity B7-H3/CD3-targeted Protein MGD009, Inflammation, Meibomian gland dysfunction	Altered Intercellular Communication	The inflammation seen in meibomian gland dysfunction (MGD) is part of its pathogenesis, and evidence of the antioxidant-inflammatory properties of omega-3 fatty acids suggests this to be an appropriate treatment for MGD.	24039409
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	C-reactive protein (CRP) is a biomarker of inflammation and a sensitive predictor of stroke, and high homocysteine (Hcy) is also associated with stroke.	24039853
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Our results demonstrate a novel role for c-Myc in the prevention of vascular pro-inflammatory phenotype, supporting an important physiological function as a central regulator of inflammation and endothelial dysfunction.	24039874
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Collectively, the findings a) indicate that interleukin expression is influenced by ras signaling and specific interleukins play an oncogenic promoter role in colorectal cancer, highlighting the molecular link between inflammation and tumorigenesis, and b) accentuate the interwoven molecular correlations as leads to new therapeutic approaches in the future.	24040001
Waldenstrom Macroglobulinemia	Altered Intercellular Communication	Fifteen cases (4%) showed variable lymphoplasmacytic inflammation thus qualifying as IAA.	24040436
Periaortitis	Altered Intercellular Communication	Variable sclerosing lymphoplasmacytic inflammation was seen either confined to the adventitia (periaortitis; mainly in males) or extending through all layers (mainly in females).	24040436
Loss, Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	In human fibrotic kidneys, tubular epithelial cells (TECs) with intact tubular basement membrane (TBM) showed loss or down-regulation of an epithelial marker (E-cadherin), de novo expression of mesenchymal markers (vimentin and fibronectin), and significant up-regulation of inducers and mediators controlling the EMT process (transforming growth factor-b1 (TGF-b1), p-Smad2/3, b1-integrin, p38 mitogen-activated protein kinase (MAPK), WNT5B and b-catenin) in the areas of interstitial inflammation and fibrosis, compared with their expression in control kidneys.	24040439
Inflammation, Left coronary artery structure	Altered Intercellular Communication	Increased inflammation and Lm (mean linear intercept) scores were observed in chronic exposed mice, indicating emphysematous changes were present in lungs of chronic exposed mice.	24040961
Inflammation	Altered Intercellular Communication	P53 expression showed significant association with H. pylori (P = 0.005), invasion depth (P = 0.029) and inflammation reaction (P = 0.008).	24042100
Inflammation, Helicobacter pylori Positive	Altered Intercellular Communication	Biopsy sections from H. pylori-positive gastritis patients revealed more severe inflammation than those of H. pylori-negative patients.	24042100
ARCN1 gene, Inflammation, Staphylococcus aureus infection, doxorubicin/procarbazine/vincristine protocol, Acute inflammation	Altered Intercellular Communication	In this study, the levels and possible processing of MK in relation to S. aureus infection of the airways were investigated, comparing COPD and VAP, thus comparing a state of disease with preceding chronic inflammation and remodeling (COPD) with acute inflammation (that is, VAP).	24043271
ARCN1 gene, Inflammation	Altered Intercellular Communication	Taken together, proteases of both bacteria and the host contribute to degradation of the antibacterial protein MK, resulting in an impaired defense of the airways, in particular, in COPD where the state of chronic inflammation could be of importance.	24043271
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Inflammation may be an important driver of residual cardiovascular risk in patients with coronary artery disease despite aggressive statin therapy.	24043299
Inflammation	Altered Intercellular Communication	Chronic inflammation as a determinant of future aging phenotypes.	24043651
Inflammation	Altered Intercellular Communication	The importance of chronic inflammation as a determinant of aging phenotypes may have been underestimated in previous studies that used a single measurement of inflammatory markers.	24043651
Inflammation	Altered Intercellular Communication	We assessed inflammatory markers twice over a 5-year exposure period to examine the association between chronic inflammation and future aging phenotypes in a large population of men and women.	24043651
Inflammation	Altered Intercellular Communication	Chronic inflammation, as ascertained by repeat measurements, was associated with a range of unhealthy aging phenotypes and a decreased likelihood of successful aging.	24043651
Inflammation	Altered Intercellular Communication	Our results suggest that assessing long-term chronic inflammation by repeat measurement of interleukin-6 has the potential to guide clinical practice.	24043651
Inflammation, Carcinogenesis	Altered Intercellular Communication	Nitric oxide (NO) is a signaling molecule that plays an important role in inflammation and carcinogenesis.	24044375
vascular inflammations	Altered Intercellular Communication	We identified by non-targeted proteomic approach and confirmed by the means of independent techniques, the differential expression of several proteins indicating significantly increased vascular inflammation response, disturbance in the lipid metabolism and in atherogenic plaques stability.	24044526
Macrovesicular hepatic steatosis, Nephritis	Altered Intercellular Communication	In adult rats, the FRU diet induced transient elevations of MAP and HR in the 6th week, and, at 13 weeks, increased fasting glucose, triglycerides, total cholesterol, AST and ALT; increased liver, kidneys and retroperitoneal fat weights; and induced macrovesicular and microvesicular NAFLD, the presence of fat cells in the kidney, glomerular sclerosis, and liver and kidney inflammation.	24044579
Communicable Diseases, Inflammation, Pseudoepitheliomatous hyperplasia	Altered Intercellular Communication	Pseudocarcinomatous hyperplasia (PH) is a marked proliferation of benign squamous epithelium lacking cytologic atypia and pleomorphism in response to chronic stimuli, such as inflammation, infection, irradiation, or an underlying neoplastic reaction.	24045190
Inflammation, home health encounter	Altered Intercellular Communication	GI inflammation was common in HH patients, which from the different perspective, supports the notion that iron overload may lead to GI inflammation.	24045277
Inflammation, Periodontitis, Ischemic stroke	Altered Intercellular Communication	Biomarkers of periodontitis and inflammation in ischemic stroke: A case-control study.	24045341
Inflammation, Endotoxemia, Periodontal Infection, Destruction of tissue	Altered Intercellular Communication	We conclude that controls more often had evidence of current periodontal infection with higher periodontal pathogen amount, endotoxemia, local inflammation and tissue destruction.	24045341
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Additionally, inflammatory burden may contribute to high systemic inflammation associated with elevated stroke susceptibility.	24045341
Inflammation, Adult Non-Hodgkin Lymphoma, RTEL1 gene	Altered Intercellular Communication	Compromised immunity and chronic inflammation are thought to contribute to the development of non-Hodgkin lymphoma (NHL).	24045922
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Genetic variation in the inflammation and innate immunity pathways and colorectal cancer risk.	24045924
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	It is widely accepted that chronic inflammation plays a role in the etiology of colorectal cancer.	24045924
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Using a two-stage design, we examined the associations between colorectal cancer and common variation in 37 key genes in the inflammation and innate immunity pathways.	24045924
Gingivitis, Anemia, Sickle Cell	Altered Intercellular Communication	There was a statistically significant association between having mild, moderate or severe gingival inflammation and the severity of sickle cell anemia (P = 0.028).	24046824
Airway structure	Altered Intercellular Communication	Fractional exhaled nitric oxide (FeNO) is a non-invasive marker of airway inflammation.	24046997
Airway structure, Asthma, IL13 gene	Altered Intercellular Communication	As FeNO is a marker of lower airway inflammation, significantly higher FeNO levels in atopic allergic rhinitis patients suggest that it may be a predictor for onset of asthma in these patients.	24046997
Inflammation, Hypertensive (finding), Hypertension, CTCAE, Metabolic Syndrome X	Altered Intercellular Communication	Chemerin is strongly associated with markers of inflammation and components of the metabolic syndrome in hypertensive subjects and was independently associated with hypertension after adjustment for age, gender and metabolic risk factors.	24047472
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Interleukin 6 (IL-6) signaling plays a role in inflammation, cancer, and senescence.	24047696
Inflammation, Malignant Pleural Mesothelioma, Pleural Tuberculosis, Empyema, Pleural Effusion, CTCAE, Secondary malignant neoplasm of pleura	Altered Intercellular Communication	The pathological diagnosis was as follows: pleural metastases in 899 (37.8%), primary pleural mesothelioma in 439 (18.4%), tuberculous pleurisy in 514 (21.6%), non-specific inflammation in 226 (9.5%), empyema in 190 (8.0%), hepatic pleural effusion in 36 (1.5%) and pleural effusion of unknown causes in 76 (3.2%) cases.	24047806
Pain Distress Question, Inflammation	Altered Intercellular Communication	The results suggest an effect of pain, which may be a possible marker of inflammation.	24047870
Giant Cell Arteritis, Inflammation, GCA gene, Autoimmune Disorder, CTCAE	Altered Intercellular Communication	Giant cell arteritis (GCA) is an autoimmune disorder characterized by the inflammation of medium to large vessels.	24048107
Inflammation	Altered Intercellular Communication	The lack of increased risk after one year suggests that an association based on shared risk factors or chronic inflammation is unlikely.	24049127
Inflammation, Calcium pyrophosphate deposition disease	Altered Intercellular Communication	All US findings indicative of peri-articular synovial inflammation were more frequently detected in patients with CPPD disease than in gouty patients.	24050142
Inflammation	Altered Intercellular Communication	In 50 out of 176 (28.4%) shoulders, US allowed the detection of at least one finding indicative of synovial inflammation.	24050142
Airway structure, Asthma	Altered Intercellular Communication	Preclinical studies suggest that interleukin-9 may be a central mediator in the development and maintenance of airway inflammation in asthma.	24050312
Inflammation, Heart failure	Altered Intercellular Communication	Oxidative stress and inflammation are hallmarks of the heart failure (HF) disease state.	24050409
Sepsis, Inflammation	Altered Intercellular Communication	Most importantly, levels of circulating U6 were significantly upregulated in sera of patients with critical illness and sepsis compared with controls and correlated with established markers of inflammation.	24052167
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Retroperitoneal fibrosis (RF) is a rare disease characterized by inflammation and fibrosis of retroperitoneal soft tissues.	24052251
Inflammation, Primary malignant neoplasm, Stomach Carcinoma	Altered Intercellular Communication	Chronic inflammation has been hypothesized to play a significant role in the aetiology of cancer, including gastric cancer.	24052422
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	In the present study, we sought to examine pre-diagnostic systemic cytokine levels in plasma, which can be seen as markers of aggregate inflammation, and risk of distal gastric cancer in a case-control study nested within the prospective Shanghai Men's Health Study.	24052422
Stomach Carcinoma	Altered Intercellular Communication	Circulating levels of eight inflammation-related cytokines were measured in the plasma collected at baseline for 180 incident cases of distal gastric cancer and 358 matched controls.	24052422
Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Systemic lupus erythematosus (SLE) is an autoimmune-mediated disease, characterized by inflammation of small arteries and arterioles.	24052468
Inflammation, Complication Aspects	Altered Intercellular Communication	Inflammation is a key component in the pathogenesis of sulfur mustard (SM)-induced skin complications.	24053005
Prostate carcinoma	Altered Intercellular Communication	RHAMM overexpression may contribute to the development of hormonal resistance in prostate cancer.	24053431
Communicable Diseases, Inflammation, Large prostate	Altered Intercellular Communication	A history of prostate enlargement or inflammation was significantly associated with higher rates of both infectious (odds ratio [OR] = 3.7) and non-infectious (OR = 2.2) complications.	24053621
Steatohepatitis, Inflammation	Altered Intercellular Communication	Loss of estrogen receptor-alpha (ER-a) in the liver is associated with hepatic steatosis and inflammation in animal models.	24054032
Inflammation, Asthma	Altered Intercellular Communication	Elevation of S100 calcium binding protein A9 in sputum of neutrophilic inflammation in severe uncontrolled asthma.	24054362
Asthma	Altered Intercellular Communication	Neutrophilic airway inflammation is frequently observed in severe uncontrolled asthma (UA) and controlled asthma (CA).	24054362
Asthma	Altered Intercellular Communication	To identify biomarkers of severe uncontrolled asthma with neutrophilic airway inflammation.	24054362
Inflammation	Altered Intercellular Communication	S100A9 in sputum may be a biomarker of neutrophilic inflammation in severe UA.	24054362
Inflammation, Osage language	Altered Intercellular Communication	CPAP therapy could partially suppress systemic inflammation in OSA patients, and substantial differences were present among the various inflammatory markers.	24054505
Inflammation	Altered Intercellular Communication	Bioabsorbable polymers on drug-eluting stents may lower the long-term risks of inflammation, delayed healing, and adverse events.	24055443
Inflammation, Ischemia	Altered Intercellular Communication	Potential role of erythropoietin receptors and ligands in attenuating apoptosis and inflammation in critical limb ischemia.	24055514
Inflammation	Altered Intercellular Communication	The in vitro experiments demonstrate that ARA 290 decreases inflammation and apoptosis of ischemic myotubes.	24055514
Inflammation, Endothelium, Renal glomerular disease	Altered Intercellular Communication	Acute transplant glomerulopathy refers to alloimmune mediated endothelial injury and glomerular inflammation that typically occurs early post-kidney transplantation.	24056179
Autoimmune Diseases, Inflammation, vasculogenesis	Altered Intercellular Communication	Unlike TGF-b1(-/-) mice, the TGF-b1(Lb3/Lb3) mice show neither embryonic lethality nor signs of multifocal inflammation, demonstrating that knock-in of the TGF-b3 ligand can prevent the vasculogenesis defects and autoimmunity associated with TGF-b1 deficiency.	24056369
Inflammation, Weight decreased	Altered Intercellular Communication	Inflammation, functional status, and weight loss during recovery from cardiac surgery in older adults: a pilot study.	24057224
BDI - Functional Impairment, Weight decreased, Inflammation	Altered Intercellular Communication	The impacts of weight loss, functional impairment, and inflammation during recovery on disability and frailty warrant further study.	24057224
Inflammation, Apoptosis, Ischemic stroke, Cerebrovascular accident	Altered Intercellular Communication	The data of this work suggests that inflammation may have a role in platelet apoptosis in stroke which may suggest a new aspect of the role of inflammation in the development of acute ischemic stroke.	24057255
Inflammation	Altered Intercellular Communication	Neutrophil-lymphocyte ratio, an emerging marker of inflammation, was independently associated with the presence of LA thrombus in patients with nonvalvular AF.	24057399
Sample Size Calculation, Fibrosis Assessment, Inflammation, AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1	Altered Intercellular Communication	Systemic sclerosis (SSc) is a multisystem autoimmune disease of unknown etiology characterized by inflammation, autoantibody production, and fibrosis.	24058548
Inflammation, Endotoxemia, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inulin controls inflammation and metabolic endotoxemia in women with type 2 diabetes mellitus: a randomized-controlled clinical trial.	24059649
Inflammation, Endotoxemia, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	It can be concluded that inulin supplementation seems to be able to modulate inflammation and metabolic endotoxemia in women with type 2 diabetes.	24059649
Inflammation, Kidney Failure, Injury of kidney	Altered Intercellular Communication	We analyzed two common genetic polymorphisms that have previously been linked to renal failure and inflammation, and have been supposed to be associated with cardiac surgery associated-acute kidney injury (CSA-AKI).	24059882
Kidney Failure, Chronic, Inflammation, Failure (biologic function)	Altered Intercellular Communication	[The effects of failure of low density lipoprotein receptor expression induced by inflammation on radial artery foam cell formation in patients with end-stage renal disease].	24059991
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	To investigate whether inflammation exacerbates lipid accumulation in the radial arteries of patients with end-stage renal disease (ESRD) and to explore its underlying mechanisms.	24059991
Inflammation	Altered Intercellular Communication	Confocal microscopy observation showed that inflammation enhanced the translocation of SCAP escorting SREBP-2 from endoplasmic reticulum to Golgi, thereby activating LDLr gene transcription.	24059991
Inflammation	Altered Intercellular Communication	Further analysis showed that dysregulation of LDLr pathway induced by inflammation was associated with increased protein expression of mTOR (r = 0.733, P < 0.05), especially with the enhanced co-expression of mTOR and SREBP-2(P < 0.05).	24059991
Kidney Failure, Chronic	Altered Intercellular Communication	Inflammation accelerates the progression of foam cell formation in ESRD patients via dysregulation of LDLr pathway, which might be partly through the activation of mTOR pathway.	24059991
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	Reciprocal relation between GADD153 and Del-1 in regulation of salivary gland inflammation in Sjogren syndrome.	24060278
Sjogrens Syndrome", Inflammation, GYPB gene	Altered Intercellular Communication	Accordingly, we tested the hypothesis that Sjogren's syndrome (SS) is associated with increased salivary gland expression of GADD153 and increased leukocyte infiltration in association with decreased Del-1 thereby contributing to inflammation and cell death.	24060278
Inflammation, Cell Death	Altered Intercellular Communication	Our collective observations suggested that GADD153 directly and/or indirectly through downregulation of Del-1 contributes importantly to salivary gland inflammation and cell death.	24060278
Inflammation	Altered Intercellular Communication	Collectively, the results indicate that GADD153 regulates inflammation and cell death in salivary gland in SS.	24060278
Sialadenitis	Altered Intercellular Communication	Further, Del-1 expression likely provides a mechanistic link between increased GADD153 and leukocyte infiltration and accompanying inflammation of salivary gland tissue in this condition.	24060278
Inflammation	Altered Intercellular Communication	Splenectomy was associated with reversals of increased pHb, RBC adhesion, reticulocytes, RBC marker expression and inflammation in HS.	24060729
Inflammation	Altered Intercellular Communication	In contrast to the normal tunica consisting of a thin fibrous wall lined by a monolayer of flattened bland mesothelium and no significant inflammation, all of our cases were characterized by background changes of fibroblastic organization and stromal chronic inflammation.	24061516
Vascular Diseases, Hemorrhage, Interstitial inflammation, Infarction, Tubular atrophy	Altered Intercellular Communication	One case showed only segmental tubular atrophy with interstitial inflammation and vasculopathy; no infarct or hemorrhage was identified.	24061519
Interstitial inflammation	Altered Intercellular Communication	Interstitial inflammation was seen adjacent to damaged testicular parenchyma in all 30 cases.	24061519
Vasculitis, CTCAE, Interstitial inflammation, Avascular Necrosis, CTCAE	Altered Intercellular Communication	All clinical acute torsion cases showed both parenchymal and fibrinoid vascular necrosis, and 10 had hemorrhage/hematoma; they lacked vasculitis, interstitial inflammation, and chronic vascular changes.	24061519
Inflammation, Heart failure, Bipolar Disorder	Altered Intercellular Communication	Inflammation may be a link between depressive symptoms and outcomes in patients with heart failure.	24062026
Inflammation, Heart failure, Bipolar Disorder	Altered Intercellular Communication	Our findings, in combination with prior researchers', suggest there is not a robust relationship between depressive symptoms and individual biomarkers of inflammation in heart failure.	24062026
Inflammation, Systemic Inflammatory Response Syndrome, Toxic effect	Altered Intercellular Communication	Patients with severe DFI, as by manifesting two or more signs of systemic inflammation or toxicity, had higher rates of major amputation and longer hospital stays and required more surgery and more subsequent admissions than patients who did not manifest SIRS.	24062324
Inflammation, Obesity	Altered Intercellular Communication	Chronic inflammation exists in population of PDC and obesity people.	24063213
Inflammation	Altered Intercellular Communication	Strict control of inflammation may result in closure of the macular hole and avoid the need for vitrectomy.	24063599
Inflammation, Behcet Syndrome	Altered Intercellular Communication	To evaluate the long-term efficacy and safety of intravitreal triamcinolone acetonide (IVTA) injection for posterior segment inflammation in Behcet disease (BD) patients.	24063666
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease is known to be associated with systemic inflammation.	24064740
Inflammation, Respiratory physiology	Altered Intercellular Communication	In the present study, we found longitudinal observational evidence that suggested that increases in systemic inflammation are associated with declines in lung function.	24064740
Inflammation, Overweight, Osteoarthritis, Knee	Altered Intercellular Communication	Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial.	24065013
TNF protein, human, Inflammation, Heart failure	Altered Intercellular Communication	TNF-a, a marker of inflammation, was significantly increased in heart failure (p = 0.004) but there was no difference between HF-D and HF-I groups; however, Galectin-3 was significantly increased in the HF-D group compared to the HF-I group (p = 0.005).	24065222
Inflammation, Carpal Tunnel Syndrome, Carotid Intima-Media Thickness	Altered Intercellular Communication	Chronic inflammation beyond the traditional cardiovascular risk factors might be related to increased carotid intima-media thickness in patients with carpal tunnel syndrome.	24065256
Inflammation, Chronic heart failure, square decimeter, Smoking	Altered Intercellular Communication	Smoking, chronic heart failure, and subclinical inflammation may be associated with high platelet reactivity in patients with DM2 treated with ASA.	24065375
Anemia	Altered Intercellular Communication	Inflammation markers were elevated (leukocytosis 22 100/ml, CRP 22 mg/dl ), there was mild anemia (hemoglobin 9.7 mg/dl) and digitoxin blood level was increased to 56 mg/l (therapeutic range 10-30 mg/l).	24065415
Pain Distress Question, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Folklore remedies for pain and inflammation in rheumatoid arthritis include the application of magnets and copper to the skin.	24066023
Fibrosis Assessment, Pneumoconiosis, Pneumonitis	Altered Intercellular Communication	Coal workers' pneumoconiosis (CWP) is characterized by chronic pulmonary inflammation and fibrotic nodular lesions that usually lead to progressive fibrosis.	24066042
Inflammation	Altered Intercellular Communication	Inflammation is the first step in the development of CWP.	24066042
Inflammation, transplantation aspects	Altered Intercellular Communication	Post-transplantation encapsulating peritoneal sclerosis without inflammation or radiological abnormalities.	24067112
Inflammation, Elastosis perforans serpiginosa	Altered Intercellular Communication	Systemic inflammation and abnormalities on an abdominal computed tomography (CT) scan are important hallmarks of EPS.	24067112
Inflammation, Elastosis perforans serpiginosa	Altered Intercellular Communication	To our knowledge, this is the first report of a case being diagnosed with late-onset post-transplantation EPS without systemic inflammation or abnormalities on a CT scan which could only be diagnosed by laparotomy.	24067112
Inflammation, Elastosis perforans serpiginosa	Altered Intercellular Communication	EPS may occur several years after kidney transplantation in the absence of inflammation and typical radiological abnormalities.	24067112
Neoplastic, Inflammation	Altered Intercellular Communication	Both angiogenesis and lymphogenesis vessels were more numerous in the areas where the inflammatory infiltrate was more abundant, which suggests that chronic inflammation plays the part of a promoter factor of neoplastic lesions.	24068414
Inflammation, Gout	Altered Intercellular Communication	Oxidized low density lipoprotein and inflammation in gout patients.	24068523
Inflammation, Gout	Altered Intercellular Communication	The changes in ox-LDL levels may be associated with enhanced inflammation in gout patients.	24068523
Communicable Diseases, Inflammation	Altered Intercellular Communication	Interestingly, although the bacteria could be found in consecutive samples taken at different points in time, there were no signs of advancing infection or inflammation.	24068980
Inflammation, Carcinogenesis, Neoplasms	Altered Intercellular Communication	Intercellular adhesion molecule (ICAM)-1, a cell adhesion molecule with a key role in inflammation and immunosurveillance, was implicated in carcinogenesis by facilitating instability in the tumor environment.	24069166
Lymphadenitis, Tuberculosis	Altered Intercellular Communication	Nasal tuberculosis is a specific inflammatory process which is, in most cases, joined by the inflammation of neck lymph nodes.	24069829
Autoimmune Diseases, Sample Size Calculation, Fibrosis Assessment, vascular inflammations	Altered Intercellular Communication	An abnormal generation of reactive oxygen species (ROS) is thought to contribute to systemic sclerosis (SSc), fostering autoimmunity, fibrosis, and vascular inflammation.	24070090
Vasculitis, Sample Size Calculation	Altered Intercellular Communication	Here we investigate whether oxidative stress regulates the cross-talk between leukocytes and platelets via HMGB1, thus contributing to vessel inflammation in SSc.	24070090
Inflammation, Osteopenia	Altered Intercellular Communication	Between-group differences were greater in patients with higher periodontal inflammation at baseline (mean -0.74 [95% CI: -1.29 to -0.19], p = 0.01) and in patients with severe bone loss at baseline (-0.61 [95% CI: -1.16 to -0.054], p = 0.03).	24070911
Inflammation	Altered Intercellular Communication	Furthermore, the changes in periodontal inflammation correlated with changes in carotid inflammation (R = 0.61, p < 0.001).	24070911
Inflammation, Periodontitis, Atherosclerosis	Altered Intercellular Communication	Given the concomitant changes observed in periodontal and arterial inflammation, these data raise the possibility that a portion of that beneficial impact of statins on atherosclerosis relate to reductions in extra-arterial inflammation, for example, periodontitis.	24070911
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	reduced caloric intake, inflammation and greater fat metabolism) may be present in older patients with cancer, along with poorer levels of functional capacity, compared to healthy controls.	24071543
Inflammation, Adverse reaction to drug, Pneumonia, Alveolar damage, Pulmonary cryptococcosis, Pneumonia, Interstitial	Altered Intercellular Communication	The increase in surface area and quality of biopsy samples translated to a high percentage of alveolated tissue (70 %) that enabled a clear histological detection of the following diagnoses: noncaseating granulomatous inflammation (n = 2), acute interstitial pneumonitis consistent with drug reaction (n = 5), nonspecific interstitial pneumonia fibrotic variant (n = 1), diffuse alveolar damage (n = 3), organizing pneumonia (n = 3), and pulmonary cryptococcal pneumonia (n = 1).	24071930
Sepsis, Inflammation	Altered Intercellular Communication	Further research is needed to determine how excess adiposity modulates inflammation from sepsis.	24072354
Malignant neoplasm of urinary bladder, Inflammation, Fibrosis Assessment, Neoplasms	Altered Intercellular Communication	To investigate the efficacy of diffusion-weighted MRI (DWI) in differentiating recurrent tumor from chronic inflammation and fibrosis after cystectomy or transurethral resection of bladder cancer.	24072383
Fibrosis Assessment, Acute inflammation, Neoplasms	Altered Intercellular Communication	The normalized apparent diffusion coefficients of recurrent tumors (0.697 +- 0.219) were significantly (P < 0.05) lower than those of postoperative inflammation or fibrosis (1.019 +- 0.143).	24072383
Bladder Neoplasm, Fibrosis Assessment, Acute inflammation	Altered Intercellular Communication	DWI is superior to DCE MRI for differentiating recurrent bladder tumors from postoperative inflammation or fibrosis.	24072383
Hyperplasia of pituitary gland, Hyperprolactinemia, Primary Hypothyroidism	Altered Intercellular Communication	Brain imaging findings showed pituitary hyperplasia; hormonal assessment revealed primary hypothyroidism and hyperprolactinemia.	24072579
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Interleukin-6 (IL-6) a pleiotropic cytokine is a central mediator of inflammation in the pathogenesis of coronary artery disease (CAD).	24072607
Inflammation, Anemia	Altered Intercellular Communication	Anemia related to inflammation dominated the different types of anemia.	24073709
Inflammation	Altered Intercellular Communication	A low-grade inflammation has been reported to occur in PI-IBS.	24073715
Constipation, Inflammation, Ichthyosis Bullosa of Siemens, Gastroenteritis	Altered Intercellular Communication	A 20-year-old female with a diagnosis of IBS with constipation (IBS-C), according to Rome III criteria, contracted Campylobacter-induced gastroenteritis, after which her symptom pattern changed to IBS-M. She showed an intestinal low-grade inflammation that was manifested by an increase in the number of intraepithelial and lamina propria leucocytes and lymphocytes and an increase in the density of mast cells in lamina propria.	24073715
Inflammation, Gastroenteritis, Post-infectious disorder	Altered Intercellular Communication	Gastroenteritis in patients with IBS-C causes a post-infectious, low-grade inflammation.	24073715
Data types - Address, Dermatitis	Altered Intercellular Communication	Collectively, our findings argue for early intervention strategies designed to mitigate skin inflammation in children with AD.	24074334
Keratoconjunctivitis, Vernal, Inflammation	Altered Intercellular Communication	Vernal keratoconjunctivitis (VKC) is a bilateral chronic, seasonally exacerbated inflammation of the ocular surface that especially affects male children and young boys.	24074451
Inflammation, Herpes zoster disease, Neuralgia	Altered Intercellular Communication	Deficiencies of these nutrients may induce dysregulated inflammation and oxidative damage leading to neuropathic pain in patients with herpes zoster.	24074834
Inflammation, SELENON gene, Cardiomyopathies	Altered Intercellular Communication	We present an original case of a 32-year-old woman with RSS with dilated a cardiomyopathy who on cardiac biopsy showed occasional hypertrophic and atrophic myocytes with no evidence of inflammation, abnormal sarcomeres and disintegration of the Z bands on ultrastructural analysis, abnormal desmin, and normal C9 immunoreactivity.	24075556
Autoimmune Diseases, Atherosclerosis	Altered Intercellular Communication	Cytotoxic CD4(+)CD28(null) cells are generated under inflammatory conditions and implicated in a variety of pathological processes like atherosclerosis and autoimmune diseases.	24075776
Inflammation	Altered Intercellular Communication	There is a low level of correlation between clinical and endoscopic and histologic subscores of patients with IPAA; clinical symptoms therefore might not reflect objective evidence of inflammation.	24075890
Inflammation	Altered Intercellular Communication	These findings, along with evidence of correlation between total scores and clinical symptoms, indicate that these indices do not accurately identify patients with pouch inflammation.	24075890
Inflammation	Altered Intercellular Communication	Further research is required to understand additional factors that contribute to clinical symptoms in the absence of objective signs of pouch inflammation.	24075890
Clinical Events Domain	Altered Intercellular Communication	CE was better than SBFT and equivalent to ileocolonoscopy in detecting small-bowel inflammation.	24075891
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus	Altered Intercellular Communication	Chronic low-grade systemic inflammation presented in Type 2 diabetes mellitus plays a major role in disease progression as well as development of micro- and macro-vascular complications of diabetes.	24076594
Inflammation, Complications of Diabetes Mellitus	Altered Intercellular Communication	Therefore, reducing inflammation can be beneficial in prevention of diabetes complications.	24076594
Inflammation, diabetic	Altered Intercellular Communication	Inflammation was associated with insulin resistance in diabetic patients.	24076594
Thrombotic Microangiopathies, Inflammation, Endocardium, Blood Clot	Altered Intercellular Communication	One of the proposed mechanisms of origin of these masses is organizing thrombi in the setting of endocardial injury and inflammation questioning a possible link to thrombotic microangiopathy.	24077148
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Oxidative stress, inflammation, and increased cholesterol levels are all mechanisms that have been associated with Alzheimer's disease (AD) pathology.	24077434
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Carotid intima media thickness, oxidative stress, and inflammation in children with chronic kidney disease.	24077647
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We evaluated the association between inflammation and oxidative stress with carotid intima media thickness (cIMT) and elasticity increment module (E(inc)) in pediatric patients with chronic kidney disease (CKD).	24077647
Inflammation	Altered Intercellular Communication	MMP-1 overexpression induced by IL-1b: possible mechanism for inflammation in degenerative lumbar facet joint.	24077757
Degeneration of lumbar intervertebral disc, Inflammation, Radiculopathy, Abnormal degeneration	Altered Intercellular Communication	More and more attention has been focused on the inflammation or degeneration caused by biochemical factors in radiculopathy during lumbar facet joint degeneration.	24077757
Inflammation, Laryngeal Nerve Paralysis	Altered Intercellular Communication	The mechanisms of vocal cord fixation can be classified into mechanical articular fixation, direct injury of the recurrent laryngeal nerve, or recurrent laryngeal nerve paralysis secondary to inflammation.	24077868
vascular inflammations, Thrombosis, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Different cell-derived MPs in CHD may indicate the different pathophysiological changes in vessels, and MPs may both participate in the development of thrombosis and enhance the vascular inflammation.	24078095
Inflammation, Pain Distress Question	Altered Intercellular Communication	In three cases, a sterile inflammation adjacent to the geneX(r) occurred, with delayed wound healing in two patients and local pain.	24078171
Inflammation, Pain Distress Question	Altered Intercellular Communication	We concluded from this series of patients that geneX(r) causes soft tissue inflammation and pain with its use.	24078171
ARCN1 gene, Inflammation	Altered Intercellular Communication	In conclusion, NLR could be considered as a new inflammatory marker for assessment of inflammation in COPD patients with its quick, cheap, easily measurable property with routine complete blood count analysis.	24078279
Vasculitis, Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Ab-related angiitis: comparison with CAA without inflammation and primary CNS vasculitis.	24078731
Cerebral Amyloid Angiopathy, Inflammation, Vasculitis, Granulomatous Angiitis	Altered Intercellular Communication	Specimens reviewed by a neuropathologist showed 40 with vascular Ab peptide without inflammation (cerebral amyloid angiopathy [CAA]), 28 with granulomatous vasculitis (Ab-related angiitis or ABRA), and 10 with perivascular CAA-related inflammation.	24078731
ARCN1 gene, Inflammation	Altered Intercellular Communication	Increased serum ox-LDL levels correlated with lung function, inflammation, and oxidative stress in COPD.	24078777
ARCN1 gene, Abnormal inflammatory response, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is associated with abnormal inflammation and high oxidative stress.	24078777
ARCN1 gene, Inflammation	Altered Intercellular Communication	This study compared serum levels of ox-LDL in 48 COPD patients and 32 health controls and correlated them with lung function, systematic inflammation, and oxidative stress.	24078777
ARCN1 gene, Inflammation	Altered Intercellular Communication	These results suggest that serum levels of ox-LDL are increased in COPD patients and that these levels are associated with lung function, inflammation, and oxidative stress in COPD.	24078777
Inflammation, Weight decreased	Altered Intercellular Communication	These results demonstrate that on a moderate carbohydrate background diet, accompanied by weight loss, the inclusion of whole eggs improves inflammation to a greater extent than yolk-free egg substitute in those with MetS.	24079288
Corneal epithelial defect, Inflammation, Infiltrate of cornea, Conjunctival hyperemia	Altered Intercellular Communication	In the development stage, marked conjunctival hyperaemia, a corneal epithelial defect, obvious corneal infiltration and progressive inflammation were seen; pathological changes comprised abundant inflammatory cells and a rounded cyst in the oedematous stroma, as well as a very small amount of neovascularization.	24079482
Inflammation, Stomach Carcinoma, Atrophic	Altered Intercellular Communication	Compared to a nongastric cancer group that was matched according to gender and age, the incidence of endoscopic atrophy (3.52 +- 1.45 vs. 4.85 +- 1.18, p < 0.001), histological atrophy at the greater curvature of the antrum (1.42 +- 0.80 vs. 1.95 +- 0.86, p = 0.0059), inflammation (2.05 +- 0.59 vs. 2.33 +- 0.66, p = 0.031), IM at the greater curvature of the corpus (0.06 +- 0.30 vs. 0.24 +- 0.54, p = 0.029), the ratio of OLGA-stage 0-II/III, IV (13/8 vs. 55/11, p = 0.038) were significantly higher for the gastric cancer group.	24079881
Inflammation, Stomach Carcinoma, Atrophic	Altered Intercellular Communication	Severe endoscopical atrophy, OLGA staging, histological atrophy at the antrum, inflammation, and particularly IM at the corpus, were identified as risk factors for gastric cancer development following H. pylori eradication.	24079881
Inflammation, Spondylitis	Altered Intercellular Communication	Macrophage phenotype in the subclinical gut inflammation of patients with ankylosing spondylitis.	24080254
Inflammation, Crohn Disease	Altered Intercellular Communication	Long-term evolution of subclinical gut inflammation to overt Crohn's disease (CD) has been described in AS patients.	24080254
Inflammation	Altered Intercellular Communication	The absence of CD14(+) macrophages together with the expansion of resolution phase and M2 macrophages is the immunological signature of subclinical ileal inflammation in AS.	24080254
Inflammation, Pain Distress Question	Altered Intercellular Communication	Targeting systemic inflammation in patients with obesity-related pain: Obesity- related pain: time for a new approach that targets systemic inflammation.	24080568
Pain Distress Question, Inflammation, Obesity, Disability, Weight decreased	Altered Intercellular Communication	We may be able to reduce pain, disability, and related comorbidities in obese patients by implementing modest weight loss and fitness interventions to address systemic inflammation.	24080568
Gallbladder Carcinoma	Altered Intercellular Communication	Evaluation of two inflammation-based prognostic scores in patients with resectable gallbladder carcinoma.	24081806
Primary malignant neoplasm	Altered Intercellular Communication	A number of inflammation-based prognostic scores have been established to help predict survival after surgery for several types of cancer.	24081806
Tissue Dissection, Inflammation	Altered Intercellular Communication	Consequently, during pedicle dissection, significant inflammation was found in the vicinity of the right portal vein.	24081808
Chronic lymphocytic inflammation, Pontine structure	Altered Intercellular Communication	CLIPPERS syndrome (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids) is an inflammatory process of the central nervous system whose distinguishing features are the enhancing punctiform lesions in the brainstem that appear in the magnetic resonance images.	24081890
Sleep-Disordered Breathing, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	Sleep disordered breathing (SDB) has been associated with oxidative stress, inflammation, and altered hormonal levels, all of which could affect the risk of cancer.	24082302
Sleep-Disordered Breathing, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	Sleep disordered breathing (SDB) has been associated with oxidative stress, inflammation, and altered hormonal levels, all of which could affect the risk of cancer.	24082302
Inflammation	Altered Intercellular Communication	These results provide additional evidence that inflammation is a factor in the mechanisms that cause incident mobility disability and suggest that a combined measure of inflammatory markers may improve prediction of functional prognosis.	24083386
methyldopa, Inflammation	Altered Intercellular Communication	Our data support the central role of inflammation in the pathogenesis of AMD and provide further evidence of a systemic involvement in AMD etiology.	24083687
Inflammation, Carcinoma of lung	Altered Intercellular Communication	In addition, smoking would be an important contributor to the processes of inflammation and lung cancer.	24083740
Inflammation	Altered Intercellular Communication	These results suggest that Yusho patients have dysregulated TH17 cell-mediated immune responses that may be linked to inflammation.	24083809
Inflammation, Heart failure, Endothelial dysfunction	Altered Intercellular Communication	Body mass index in chronic heart failure: association with biomarkers of neurohormonal activation, inflammation and endothelial dysfunction.	24083942
Arterial Stiffness, Inflammation, Hypertensive heart disease	Altered Intercellular Communication	Markers of inflammation and arterial stiffness were lowest in the normotensive group and highest in patients with hypertensive heart disease; endothelial markers were similar between groups.	24084214
Arterial Stiffness, Inflammation	Altered Intercellular Communication	In conclusion, markers of inflammation and arterial stiffness are independently related to BP.	24084214
Inflammation, Primary malignant neoplasm, Neoplasm Metastasis	Altered Intercellular Communication	The concept of the involvement of systemic inflammation in cancer progression and metastases has gained attraction within the past decade.	24084772
Pneumonitis	Altered Intercellular Communication	Global lung parenchymal glycolysis and lung parenchymal SUVmean may serve as potentially useful biomarkers to quantify lung inflammation on FDG PET/CT following thoracic radiation therapy.	24085504
Inflammation	Altered Intercellular Communication	Pre-diabetes is characterized by increased cardiovascular risk and chronic inflammation.	24085683
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Perceived stress and coping strategies may influence the risk of cardiovascular disease through their possible association with inflammation, but data remain controversial for perceived stress or scanty for coping strategies.	24085705
HIV Antigens, Atherosclerosis	Altered Intercellular Communication	Monocytes play a pivotal role in atherosclerosis, and may be major mediators of HIV-associated inflammation.	24086545
Inflammation, HIV Infections, Cardiovascular Diseases	Altered Intercellular Communication	Hyper-inflammatory IL-1b enriched monocytes may be a major source of IL-6 production and systemic inflammation in HIV-infected adults, and may contribute to the risk for all-cause mortality and cardiovascular disease in treated HIV infection.	24086545
Inflammation, Muscle degeneration	Altered Intercellular Communication	Transgenic FHL1 expression increased sarcolemmal membrane stability, reduced muscle degeneration, decreased inflammation and conferred protection from contraction-induced injury in mdx mice.	24087791
Airway structure, ARCN1 gene	Altered Intercellular Communication	Respiratory viral detection and small airway inflammation in lung tissue of patients with stable, mild COPD.	24088037
Airway structure	Altered Intercellular Communication	The two groups were compared for viral prevalence and load, and airway inflammation.	24088037
ARCN1 gene, influenza A virus	Altered Intercellular Communication	Lung tissue of COPD patients had a significantly higher prevalence of viral nucleic acid (particularly influenza A virus), and increased inflammation of small airways by macrophages and neutrophils versus controls.	24088037
ARCN1 gene, Inflammation	Altered Intercellular Communication	The lung tissue of patients with stable, mild COPD has a higher prevalence and load of respiratory viruses versus non-obstructed control subjects, and increased inflammation of small airways.	24088037
ARCN1 gene, Airway structure	Altered Intercellular Communication	Cigarette smoking is the major risk factor for COPD, leading to chronic airway inflammation.	24088173
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	We hypothesized that cigarette smoke induces structural and functional changes of airway epithelial mitochondria, with important implications for lung inflammation and COPD pathogenesis.	24088173
Inflammation, Cardiac dysfunction	Altered Intercellular Communication	Influence of cardiac dysfunction and systemic inflammation on pulmonary function and airway responsiveness in obese subjects.	24088331
Inflammation, Dyslipidemias, Dysglycemia	Altered Intercellular Communication	Altered cardiac function, dysglycemia and dyslipidemia do not seem to be significantly associated with AHR in severely obese subjects in contrast to systemic inflammation.	24088331
vascular inflammations	Altered Intercellular Communication	Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a specific biomarker specific for vascular inflammation.	24089018
Inflammation, Dental Plaque	Altered Intercellular Communication	Inflammation has a significant association with plaque progression.	24089018
HD Term Type, Inflammation, Cachexia, Overhydration	Altered Intercellular Communication	Protein-energy wasting (PEW), associated with inflammation and overhydration, is common in haemodialysis (HD) patients and is associated with high morbidity and mortality.	24089158
HD Term Type, Inflammation	Altered Intercellular Communication	Assess the relationship between nutritional status, markers of inflammation and body composition through bioimpedance spectroscopy (BIS) in HD patients.	24089158
glycation	Altered Intercellular Communication	The receptor for advanced glycation end products (RAGE) is an inflammation-perpetuating receptor, and soluble RAGE (sRAGE) is a marker of cellular RAGE expression.	24089588
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Recent studies have shown that the presence of systemic inflammation correlates with poor survival in various of cancers.	24089602
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	The latter can be considered as target for suppression of inflammation and achievement of stabilization of atherosclerotic plaque.	24090379
Inflammation	Altered Intercellular Communication	She also had myodesospsia, syphilids and syphilitic roseola, together with laboratory indicators of inflammation.	24090892
Inflammation, Hernia	Altered Intercellular Communication	The hernia sac can be used to repair the inguinal hernia because it's a patient's tissue with no inflammation and rejection.	24091173
ARCN1 gene, Inflammation	Altered Intercellular Communication	COPD is also characterized by low-grade systemic inflammation.	24091482
ARCN1 gene, Inflammation	Altered Intercellular Communication	However, the relationship between physical activity and systemic inflammation in COPD is unclear.	24091482
ARCN1 gene, Inflammation	Altered Intercellular Communication	These results provide the conceptual basis to study whether an intervention to promote walking will reduce systemic inflammation in people with COPD.	24091482
Inflammation, Mediastinitis	Altered Intercellular Communication	A two-staged strategy to treat postoperative mediastinitis was scheduled, i.e., the setting up of a vacuum-assisted closure system until the improvement of inflammation followed by wound closure with pedicled omental grafting.	24091537
Necrosis with inflammation	Altered Intercellular Communication	Inflammasome components and necro-inflammation were evaluated in acinar cells by immunofluorescence (IF), histology, and biochemical approaches.	24091659
Airway structure, ARCN1 gene	Altered Intercellular Communication	Airway inflammation, including excess nitric oxide generation in the peripheral airways, might be related to the pathophysiology of COPD.	24091810
Granulomatous inflammation, Sarcoidosis, Pulmonary Fibrosis	Altered Intercellular Communication	This may be useful in identifying exhaled biomarkers of granulomatous inflammation and pulmonary fibrosis in patients with sarcoidosis.	24091835
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	EBC markers of granulomatous inflammation are detectable at greater levels in patients with sarcoidosis compared to healthy controls subjects.	24091835
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	Our data demonstrate a previously unknown multi-targeted involvement of TNF-a in PDA lipogenesis and inflammation and metastasis and suggest that intratumoral introduction of TNF-a may have the potential as a novel therapeutic approach in human PDA.	24091913
Inflammation, Infection, Cerebrovascular accident	Altered Intercellular Communication	There is good evidence that respiratory and other infections that cause systemic inflammation can trigger strokes; however, the role of specific infections is unclear.	24092802
Joint laxity, CLEFT LIP/PALATE WITH ABNORMAL THUMBS AND MICROCEPHALY, Microspectrophotometry, Chronic musculoskeletal pain, Pain	Altered Intercellular Communication	Chronic musculoskeletal pain (MSP) is common in children and can be due to several non-inflammatory conditions such as the benign joint hypermobility syndrome (BJHS), and growing pains (GP).	24093536
Inflammation	Altered Intercellular Communication	There were cases of inflammation seen in axial images of a 3D T1-weighed gradient echo sequence not reflected in the perfusion data.	24093565
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Colliquation found on the ultrasound images led to a biopsy, the result of which indicated only an inflammation, without any malignancy.	24093821
Granulomatous inflammation	Altered Intercellular Communication	This excluded the presence of a foreign body but showed that the left main bronchus was partially obstructed with caseous material and showed significant signs of granulomatous inflammation on the wall.	24094042
Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Diabetes Mellitus, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	In view of recent evidence that serum creatinine and dysfunctional apolipoprotein (apo)A-I may serve as inflammation mediators in people with enhanced inflammation, we studied whether or not these molecules were interrelated and associated with coronary heart disease (CHD) likelihood even in subjects without metabolic syndrome (MetS) or type-2 diabetes.	24094290
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Multiple modified gene transcripts involved in inflammation, cytoprotection, and neurodegeneration were correlated with neurocognitive functioning.	24094461
Inflammation, Coronary Arteriosclerosis, Atrial Fibrillation by ECG Finding, Coronary Artery Disease	Altered Intercellular Communication	Predictors of postoperative atrial fibrillation in patients with coronary artery disease undergoing cardiopulmonary bypass: a possible role for myocardial ischemia and atrial inflammation.	24094564
Inflammation, Atrial Fibrillation by ECG Finding, Coronary Arteriosclerosis, osteoclast activating factor, Coronary Artery Disease	Altered Intercellular Communication	To evaluate the preoperative presence of C-reactive protein (CRP) and troponin T(hs-TnT) in patients with coronary artery disease (CAD) undergoing cardiopulmonary bypass (CPB) in order to better clarify the role of atrial inflammation and/or myocardial ischemia in the development of postoperative atrial fibrillation (POAF).	24094564
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Inflammation is considered as a mechanism leading to depression, but the association between inflammatory dietary pattern and depression risk is unknown.	24095894
Inflammation, Depression, CTCAE	Altered Intercellular Communication	This finding suggests that chronic inflammation may underlie the association between diet and depression.	24095894
Shock, Inflammation	Altered Intercellular Communication	Heat shock protein 70 (HSP70) plays a critical role in the process of inflammation and innate immunity response under environmental stress.	24095952
Inflammation, Primary malignant neoplasm, Necrosis	Altered Intercellular Communication	Therapeutic response was assessed histopathologically as grade 0 to 3, based on the degree of disappearance of cancer cells, displacement by necrotic and fibrotic tissue, and tumor-induced inflammation.	24096109
Inflammation, Obesity, Pain Distress Question	Altered Intercellular Communication	Association of obesity with inflammation and pain after total hip arthroplasty.	24096457
Inflammation, Obesity, Pain Distress Question	Altered Intercellular Communication	Larger studies exploring the specific impact of obesity and inflammation on surgical outcomes, including pain, are warranted.	24096457
Inflammation, Chronic sinusitis	Altered Intercellular Communication	Chronic rhinosinusitis is a symptomatic inflammation of the mucosa of the nose and paranasal sinuses lasting for at least 12 weeks.	24096817
Inflammation	Altered Intercellular Communication	One lesion was considered a benign finding from inflammation demonstrated by clinical follow-up.	24096999
Inflammation, Sarcopenia, Osteoporosis	Altered Intercellular Communication	Biological (inflammation, loss of hormones), clinical (sarcopenia, osteoporosis etc.	24097023
Inflammation, Sarcopenia, Osteoporosis	Altered Intercellular Communication	Biological (inflammation, loss of hormones), clinical (sarcopenia, osteoporosis etc.	24097023
Inflammation, Overactive bladder syndrome	Altered Intercellular Communication	Increased serum adipokines implicate chronic inflammation in the pathogenesis of overactive bladder syndrome refractory to antimuscarinic therapy.	24098552
Inflammation, Overactive Bladder	Altered Intercellular Communication	Recent studies have shown that chronic inflammation is involved in overactive bladder (OAB) syndrome.	24098552
Neurogenic Inflammation	Altered Intercellular Communication	OAB could be a subtype of neurogenic inflammation.	24098552
Inflammation	Altered Intercellular Communication	Adiponectin plays an important role in the regulation of tissue inflammation.	24099881
Inflammation, Fibrosis Assessment, Hypertrophy	Altered Intercellular Communication	We aimed to investigate telomere length in whole adipose tissue and isolated adipocytes in relation to adiposity, adipocyte hypertrophy and adipose tissue inflammation and fibrosis.	24100424
Inflammation, Units Of Measure - Siemens	Altered Intercellular Communication	Our results suggest that maintenance of high mitochondrial transcription and lack of inflammation in SAT are associated with low liver fat and MHO.	24100782
Stomach Carcinoma, Gastritis	Altered Intercellular Communication	In conclusion, functional polymorphisms of NFKB1 are associated with an increased risk of gastric cancer; in particular they are closely associated with the development of diffuse type of gastric cancer via severe gastric inflammation.	24101096
Inflammation, GDC Disease Response Terminology	Altered Intercellular Communication	The results require confirmation but are consistent with greater hypercoagulabilty and inflammation, as measured by higher levels of PAI-1 and fibrinogen, being related to DR and responsiveness to INT.	24101699
Inflammation, Swelling, Edema	Altered Intercellular Communication	Corticosteroid transdermal delivery to target swelling, edema and inflammation following facial rejuvenation procedures.	24101860
Inflammation, Swelling, Edema	Altered Intercellular Communication	The present study supports the use of Betesil(r) plaster immediately after facial cosmetic procedures in order to safely control swelling, edema, and inflammation.	24101860
Inflammation, Fibrosis Assessment, Coronary Artery Disease	Altered Intercellular Communication	Galectin-3, as a biomarker of inflammation and fibrosis, has been reported to be associated with coronary artery disease.	24102091
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	COPD is characterized by systemic inflammation, which is enhanced during exacerbations and may be assessed by measuring serum C-reactive protein (CRP).	24102428
Neoplasms	Altered Intercellular Communication	We found that tumour size, tumour weight, hormonal function and the Weiss system are all high-efficacy criteria for differentiating malignant from benign tumours (P < 0.001).	24102952
Inflammation, Ulceration, CTCAE, Scab	Altered Intercellular Communication	Monitoring during imiquimod treatment revealed impaired image quality most likely caused by inflammation, crusting and ulceration.	24103017
Inflammation, Neoplasms, Venous Invasion	Altered Intercellular Communication	Infiltration of T-cells was related to early tumour stage, expanding growth pattern and lower levels of venous invasion but was not influenced by host characteristics or degree of systemic inflammation.	24103145
Inflammation, Lipoma	Altered Intercellular Communication	These facts suggested some possibility of the relationship between inflammation and the occurrence, growth of lipoma.	24105121
Inflammation	Altered Intercellular Communication	Magnetic resonance scanning revealed a marked increase in inflammation of the brainstem (Figure 1c).	24105316
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Association of circulating vitamin D concentrations with intestinal but not systemic inflammation in inflammatory bowel disease.	24105392
Gastrointestinal inflammation	Altered Intercellular Communication	Despite total, free, and bioavailable 25(OH)D concentrations being similar to those in a healthy control population, they inversely correlated strongly with intestinal inflammation.	24105392
Inflammation, Cholelithiasis	Altered Intercellular Communication	Patients (n = 122) with symptomatic gallstone disease, intact papilla and no ongoing inflammation, were prospectively enrolled in this case-control designed study.	24106403
Inflammation	Altered Intercellular Communication	IL-33, a newly found cytokine which is involved in joint inflammation, could be blocked by a decoy receptor-sST2.	24106520
Periodontitis, Coronary heart disease	Altered Intercellular Communication	Periodontitis is the most common chronic inflammatory condition worldwide and is associated with incident coronary disease.	24106721
Cardiac valve calcification, Periodontal Diseases	Altered Intercellular Communication	In a multiracial population, we found a significant association between the degree of periodontal disease, a chronic inflammatory condition, and cardiac calcification.	24106721
Multiple Organ Failure, Inflammation, Observation Method - Coagulation, Disseminated Intravascular Coagulation, SLC25A10 gene	Altered Intercellular Communication	Disseminated intravascular coagulation (DIC) and multiple organ failure often occur via the crosstalk between inflammation and coagulation, which is mediated by High Mobility Group Box 1 (HMGB1).	24107274
Inflammation, Restenosis, Vascular System Injuries	Altered Intercellular Communication	We hypothesized that mechanical stress imposed on the stent edge would cause vessel wall injury and inflammation, which may consequently lead to edge restenosis.	24107326
Inflammation, Ischemic stroke	Altered Intercellular Communication	Increasing evidence shows that inflammation plays an important role in the occurrence and progression of acute ischemic stroke.	24107402
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	The polymorphisms at -374 and -429 loci did not influence the stroke risk and the above mentioned inflammation cytokines.	24107402
Inflammation, Ileitis, Crohn Disease	Altered Intercellular Communication	We aimed to evaluate the de novo inflammation developing in the ileal pouch, hypothesizing that it may be similar to ileitis in Crohn's disease (CD).	24108111
Inflammation, Tuberculosis, Leishmaniasis	Altered Intercellular Communication	Gene ontology analyses revealed multiple biological processes associated with pouch inflammation, including response to chemical stimulus, small molecule metabolic and immune system processes, and specific infection-related pathways such as Staphylococcus aureus, leishmaniasis, and tuberculosis.	24108111
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Gene alterations in pouch inflammation and CD overlap, suggesting that inflammatory bowel diseases is a spectrum, rather than distinct diseases.	24108111
Psychotic Disorders, Inflammation, Heart Diseases, Rheumatoid Arthritis, Juvenile psoriatic arthritis, Dissociative disorder, Delirium	Altered Intercellular Communication	Juvenile psoriasis was associated with numerous significant comorbidities such as rheumatoid arthritis and inflammation (2.1%); delirium, psychosis, and psychotic and dissociative disorder (1.1%); and heart disease (0.6%).	24111584
Inflammation, Pneumonia	Altered Intercellular Communication	Previous studies suggest that dendritic cells and macrophages play an important role in inflammation of eosinophilic pneumonia.	24111618
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In the NCRT group, patents with moderate to severe fibrosis or grade 2 inflammation had poorer survival than those with mild fibrosis (P = 0.04) or those with grade 0 or grade 1 inflammation (P = 0.003), respectively.	24111684
Fibrosis of pancreas, Cell Aggregation, Inflammation	Altered Intercellular Communication	Non-neoplastic pancreatic tissue from patients who received NCRT had a reduced density of high-grade PanIN lesions, more pancreatic fibrosis, and higher frequencies of neuroma-like nerve proliferation and islet cell aggregation, but less inflammation, compared to tissue from those who did not receive NCRT.	24111684
Inflammation	Altered Intercellular Communication	Increase in intraocular pressure (IOP) at the time of inflammation was seen in 10 cases (27.78%).	24111839
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Cigarette smoke induces an acute but persisting inflammation in peripheral blood and airway in chronic obstructive pulmonary disease (COPD), and CD8(+) Tc-lymphocytes are considered as a key role in this process.	24112150
Delirium, Inflammation	Altered Intercellular Communication	The relationship between inflammation and delirium remains to be determined.	24112153
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	However, whether this phenomenon persists in CHD patients, a disease related to inflammation, is unknown.	24112159
Inflammation, Hyaline degeneration, Neoplasms, Dense fibrous connective tissue, Osteogenesis, Calcinosis	Altered Intercellular Communication	Pathological examination yielded a diagnosis of fibrous connective tissue with hyaline degeneration, calcification and ossification with no indication of neoplasia or inflammation.	24112395
Inflammation	Altered Intercellular Communication	Unlike other ICK cases in which there is minimal stromal inflammation, the patient presented with an intense inflammatory reaction in the anterior chamber.	24113463
Arthralgia, Inflammation	Altered Intercellular Communication	Strenuous, high-volume exercise is often associated with inflammation and joint pain.	24113700
Inflammation	Altered Intercellular Communication	Immune cell-mediated inflammation and the early improvements in glucose metabolism after gastric banding surgery.	24114113
Inflammation	Altered Intercellular Communication	We hypothesised that early changes in glucose metabolism following gastric banding surgery may relate to systemic inflammation, particularly cell-mediated immunity.	24114113
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The contribution of immune cell-mediated inflammation to glucose homeostasis in type 2 diabetes and its improvement after bariatric surgery require further investigation.	24114113
Inflammation, atherosclerotic	Altered Intercellular Communication	Combined 18F-FDG PET-CT and DCE-MRI to assess inflammation and microvascularization in atherosclerotic plaques.	24114456
Inflammation, atherosclerotic	Altered Intercellular Communication	This study determines whether there is a correlation between inflammation and neovascularization in atherosclerotic carotid plaques.	24114456
Inflammation	Altered Intercellular Communication	The pathophysiology of this syndrome may relate to overuse and inflammation.	24114651
Diarrhea, Oral pain, Nausea, Inflammatory disease of mucous membrane, Fatigue	Altered Intercellular Communication	The most frequently occurring adverse events were nausea, oral pain, fatigue, diarrhea, and mucosal inflammation.	24114811
Inflammation, Primary malignant neoplasm, Nasopharyngeal carcinoma, Rhinosinusitis	Altered Intercellular Communication	Although it is already known that the inflammation process elevates the risk of developing cancer, to date the association between rhinosinusitis and nasopharyngeal carcinoma (NPC) remains unknown.	24114992
Urinary tract infection, Diabetes Mellitus	Altered Intercellular Communication	Preliminary results suggest that UTI levels could represent a useful marker of chronic inflammatory condition in type 1 and 2 diabetes.	24115191
Metabolic Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Strict vegetarian diet improves the risk factors associated with metabolic diseases by modulating gut microbiota and reducing intestinal inflammation.	24115628
Inflammation, physiopathological, Dysbiosis	Altered Intercellular Communication	Low-grade inflammation of the intestine results in metabolic dysfunction, in which dysbiosis of the gut microbiota is intimately involved.	24115628
Inflammation, Metabolic Diseases	Altered Intercellular Communication	This study underscores the benefits of dietary fibre for improving the risk factors of metabolic diseases and shows that increased fibre intake reduces gut inflammation by changing the gut microbiota.	24115628
Inflammation, Reperfusion Injury	Altered Intercellular Communication	Beyond this, McCord's career is distinguished for bridging the gap from basic science to clinical relevance by showing the application of SOD and superoxide to human physiology, and characterizing the physiological functions of superoxide in inflammation, immunological chemotaxis, and ischemia-reperfusion injury, among other disease conditions.	24117164
Celiac Disease, Gastrointestinal inflammation	Altered Intercellular Communication	The majority of deleterious health consequences of coeliac disease (CD) are most likely to be secondary to intestinal inflammation; hence, mucosal recovery is a desirable goal of therapy.	24117503
Inflammation	Altered Intercellular Communication	This defect in mucosal immunity is associated with eosinophilic, Th2-related inflammation.	24117840
Localized scleroderma, Inflammation, Scleroderma	Altered Intercellular Communication	Perineural inflammation in morphea (localized scleroderma): systematic characterization of a poorly recognized but potentially useful histopathological feature.	24117981
Localized scleroderma, Inflammation	Altered Intercellular Communication	The association between morphea and perineural inflammation has been reported sporadically but never studied systematically.	24117981
Localized scleroderma, Inflammation	Altered Intercellular Communication	Perineural inflammation was identified in 84% and 61% of morphea and control cases, respectively.	24117981
Localized scleroderma, Inflammation	Altered Intercellular Communication	Mean perineural inflammation score in morphea (0.65) was significantly higher than in the control group (0.23) (p < 0.0001) and the inflammation tended to show a concentric pattern with plasma cell neurotropism.	24117981
Localized scleroderma, Inflammation	Altered Intercellular Communication	Intraneural inflammation was limited to four morphea cases.	24117981
Localized scleroderma, Inflammation	Altered Intercellular Communication	Although perineural inflammation is common in morphea, it is not unusual to find this feature in other inflammatory conditions.	24117981
Localized scleroderma, Inflammation	Altered Intercellular Communication	Nevertheless, perineural inflammation can serve as an important diagnostic adjunct in difficult cases of morphea if one considers its greater intensity, predominantly concentric pattern and the tendency to show plasma cell neurotropism.	24117981
Localized scleroderma, Inflammation	Altered Intercellular Communication	Although perineural inflammation is common in morphea, it is not unusual to find this feature in other inflammatory conditions.	24117981
Psoriatic Juvenile Idiopathic Arthritis, Inflammation	Altered Intercellular Communication	Psoriatic patients are at greater risk of oxidative stress and inflammation which is associated with abnormal plasma lipid metabolism and lipid peroxidation.There is not any information about the clinical significance of relation between methylentetrahydrofolatereductase (MTHFR) 677-T allele with malondialdehyde (MDA), lipids, apolipoproteins and vascular adhesion protein-1 (VAP-1) partakes in the migration process of lymphocytes into sites of inflammation.	24118377
Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Chronic systemic inflammation, a non traditional risk factor of cardiovascular diseases, is associated with increasing mortality in chronic kidney disease, especially peritoneal dialysis patients.	24118730
Inflammation, Periodontitis	Altered Intercellular Communication	Periodontitis is a potential treatable source of systemic inflammation in peritoneal dialysis patients.	24118730
Inflammation, Periodontitis	Altered Intercellular Communication	Periodontitis is an important source of chronic systemic inflammation in peritoneal dialysis patients.	24118730
Inflammation, Periodontal Diseases	Altered Intercellular Communication	Treatment of periodontal diseases can improve systemic inflammation, nutritional status and erythropoietin responsiveness in peritoneal dialysis patients.	24118730
Inflammation, Neoplasms	Altered Intercellular Communication	MicroRNA-218 (miR-218) can function as a tumour suppressor and inactivate cancer-promoting inflammation.	24118778
Ulcerative Colitis	Altered Intercellular Communication	This may cause increased proliferation of C-cell cultures, a defining initiating feature in the inflammation-carcinoma pathway in UC.	24118792
Inflammatory abnormality of the eye	Altered Intercellular Communication	Visual acuity, intraocular pressure, corneal thickness, corneal endothelial cell and ocular inflammation were examined.	24119034
Fibrinoid necrotizing inflammation, Destruction (action)	Altered Intercellular Communication	This factor may have a pathological role in RA joint destruction caused by PMNs and coinciding with rheumatoid inflammation, which suggests that PMNs, via superoxide generation, play an important role in RA joint destruction.	24119062
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Hepcidin has emerged as a peptide with a key role in the regulation of iron homeostasis in patients with chronic kidney disease (CKD), having a strong dependence on inflammation.	24119290
Inflammation, hepcidin, Atherosclerosis	Altered Intercellular Communication	This study was performed to analyze the relation of hepcidin to markers of atherosclerosis and inflammation in patients on dialysis.	24119290
Inflammation, hepcidin, Atherosclerosis	Altered Intercellular Communication	This probably suggests that hepcidin may play a role to the progression of atherosclerosis and inflammation, but this hypothesis should be further evaluated.	24119290
Autoimmune Diseases, "Sjogrens Syndrome", Xerostomia, Keratoconjunctivitis Sicca, Chronic lymphocytic inflammation	Altered Intercellular Communication	Primary Sjogren's syndrome is an autoimmune disease that presents with xerostomia and keratoconjunctivitis sicca (due to chronic lymphocytic inflammation of the salivary and lacrimal glands) and in some cases extraglandular features.	24119527
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) is characterized by inflammatory cell migration into sinus tissue with resultant inflammation fueled by a milieu of cytokines.	24119601
Inflammation	Altered Intercellular Communication	Fibroblasts may contribute to inflammation through expression of leukocyte adhesion molecules such as vascular cell adhesion molecule (VCAM) and intercellular adhesion molecule (ICAM).	24119601
Inflammation, Data types - Address	Altered Intercellular Communication	However, a bubble is expected to entrap Nitric Oxide (NO), which leads theoretically to a decrease in its bioavailability, and is expected to trigger a guanylyl-cyclase-mediated inflammatory cascade, that could explain the inflammation in AD.	24119763
Inflammation, Complex Regional Pain Syndromes, Dystonia Disorders	Altered Intercellular Communication	Our findings point at a catabolic state in chronic CRPS patients with dystonia that is likely associated with inflammation.	24120462
Inflammation, Cerebral Hemorrhage	Altered Intercellular Communication	Visfatin is linked to inflammation and associated with clinical outcomes of intracerebral hemorrhage.	24120704
Airway structure, Asthma	Altered Intercellular Communication	Chronic airway inflammation is a central process in asthma.	24121577
Airway structure	Altered Intercellular Communication	Measurement of exhaled nitric oxide (eNO) is a non-invasive biomarker of eosinophilic airway inflammation.	24121577
Inflammation, Hypopituitarism	Altered Intercellular Communication	Patients were treated by high-dose corticosteroid therapy resulting in the resolution of local inflammation but not of pituitary deficiencies.	24122241
Inflammation	Altered Intercellular Communication	This effect modification suggests that the impact of chronic inflammation may be independent of excess body fat.	24122448
Colitis	Altered Intercellular Communication	Future research is recommended to confirm emerging data that elevated serologic CRP might reflect underlying colonic inflammation.	24122448
Malignant tumor of colon, Inflammation	Altered Intercellular Communication	AIM/ BACKGROUND: The neutrophil-to-lymphocyte ratio (NLR), a combined indicator of inflammation and immunology, is as yet unidentified regarding the clinical outcome of stage II and III colon cancer patients.	24123035
Inflammation, Metabolic Diseases, Obesity	Altered Intercellular Communication	Influenced by pathogen exposure and obesity, inflammation provides a critical biological pathway linking changing environments to the development of cardiometabolic disease.	24123588
Communicable Diseases, Inflammation, Acute inflammation, Overweight	Altered Intercellular Communication	History of infectious (RRR 1.28, 95%CI 1.08-1.52) and non-communicable (RRR 1.37, 95%CI 1.12-1.69) disease, overweight (RRR 1.66, 95%CI 1.45-1.89) and high waist circumference (RRR 1.63, 95%CI 1.42-1.87) were independently associated with a greater likelihood of moderate inflammation in adults while history of infectious disease (RRR 1.87, 95%CI 1.35-2.56) and overweight (RRR 1.40, 95%CI 1.04-1.88) were independently associated with acute inflammation.	24123588
Inflammation	Altered Intercellular Communication	Environmental pathogenicity was associated with a reduced likelihood of moderate inflammation, but a greater likelihood of acute inflammation in adults.	24123588
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	SNP rs2447867 might be related to the severity of gastric epithelial injury due to inflammation and, thus, to the risk of developing gastric cancer.	24124332
Inflammation	Altered Intercellular Communication	Increasing evidence indicates that inflammation is important in disease pathophysiology.	24124488
Pneumonitis	Altered Intercellular Communication	Future research should determine whether NF-kB activation is a driver or bystander of pulmonary vascular inflammation and if the former, its potential role as a therapeutic target.	24124488
Sepsis, Inflammation	Altered Intercellular Communication	Its importance in inflammation and human sepsis is unknown.	24124588
Sepsis, Inflammation	Altered Intercellular Communication	Further studies are required to clarify the role of the N/OFQ system in inflammation and sepsis, and the mechanisms involved.	24124588
glycation, vascular inflammations, Atherosclerosis	Altered Intercellular Communication	The receptor for advanced glycation end products (RAGE) has emerged as a central regulator of vascular inflammation and atherosclerosis.	24124651
HD Term Type, Inflammation	Altered Intercellular Communication	This study demonstrated that the circulating sRAGE level was inversely associated with VCS in HD patients independent of the S100A12 level and the severity of systemic inflammation.	24124651
Venous Thromboembolism	Altered Intercellular Communication	[Dynamic changes of inflammation-related indices in venous thromboembolism and the association between these indices and venous thromboembolism].	24124734
Venous Thromboembolism, vinyltriethoxysilane	Altered Intercellular Communication	To evaluate the dynamic changes of inflammation-related indices in blood during the development of venous thromboembolism (VTE) and the association between these indices and VTE.	24124734
vinyltriethoxysilane	Altered Intercellular Communication	Some inflammation-related indices frequently used in clinical settings become elevated in VTE patients.	24124734
Inflammation, Tumor necrosis, Obesity	Altered Intercellular Communication	Body image dissatisfaction uniquely predicted inflammation biomarkers, C-reactive protein and tumour necrosis factor-a, even when controlled for obesity indicators.	24125028
Inflammation	Altered Intercellular Communication	Results contribute to the knowledge base of the complex pathways in the association between psychological factors and physical illness and some important attempts were made to explain the psychological pathways linking cognitions with inflammation.	24125028
Inflammation	Altered Intercellular Communication	The causes are not fully known, but inflammation plays a pathogenic role.	24125405
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Biomarkers reflective of mucosal and bowel wall inflammation would be useful to monitor disease activity.	24126633
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Combinations of fecal calprotectin and serum MMP9 for UC, and combinations of fecal calprotectin, serum MMP9, and serum interleukin-22 in CD, demonstrated the strongest association with imaging/endoscopy-defined inflammation.	24126633
Diastolic dysfunction, Inflammation	Altered Intercellular Communication	We hypothesized that serum 25-hydroxyvitamin D [25(OH)D] levels would be inversely associated with inflammation and with diastolic dysfunction.	24126766
Inflammation, atherosclerotic, Necrosis	Altered Intercellular Communication	Rupture-prone atherosclerotic plaques are characterized by inflammation and a large necrotic core.	24126878
Inflammation, Dental Plaque, Necrosis	Altered Intercellular Communication	Therefore, we investigated whether plaque AGEs are increased in human carotid rupture-prone plaques and are associated with plaque inflammation and necrotic core formation.	24126878
Inflammation	Altered Intercellular Communication	Furthermore, this study suggests a cascade linking inflammation, reduced GLO-1, methylglyoxal- and AGE-accumulation, and subsequent apoptosis.	24126878
Refractory anemias, Inflammation	Altered Intercellular Communication	These data suggest that HTLV-I-positive patients with RA had higher inflammation and greater resistance to anti-TNF treatment than HTLV-I-negative patients.	24127184
Inflammation, Pain Distress Question, Rheumatoid Arthritis, Depression, CTCAE, Alexithymia	Altered Intercellular Communication	Alexithymia, depression, inflammation, and pain in patients with rheumatoid arthritis.	24127403
Inflammation, Pain Distress Question, Refractory anemias, Rheumatoid Arthritis, Depression, CTCAE	Altered Intercellular Communication	We previously reported that depression and inflammation have independent effects on pain severity in patients with rheumatoid arthritis (RA).	24127403
Alexithymia, Inflammation, Depression, CTCAE, Pain Distress Question	Altered Intercellular Communication	A broad association between alexithymia and various health problems has been suggested, including depression, inflammation, and pain.	24127403
Alexithymia, Inflammation, Depression, CTCAE, Pain Distress Question	Altered Intercellular Communication	The objective of this study was to examine the independent influence of alexithymia on pain perception and its relationship to depression and inflammation.	24127403
Alexithymia, Inflammation, Depression, CTCAE, Pain Distress Question	Altered Intercellular Communication	An interaction was observed among alexithymia, depression, and inflammation with regard to perceived pain.	24127403
Inflammation, Diffuse alveolar hemorrhage, Capillaritis	Altered Intercellular Communication	Causes of distal or diffuse alveolar hemorrhage are divided by the histologic presence or absence of capillaritis, which is characterized by inflammation of the alveolar interstitium and pulmonary capillary structure.	24127476
Inflammation	Altered Intercellular Communication	The epidermal growth factor also plays an important role in regulating multiple facets of cutaneous wound healing, including inflammation, wound contraction, proliferation, migration, and angiogenesis.	24127898
Inflammation, Psoriasis, Precocious atherosclerosis	Altered Intercellular Communication	Severe psoriasis has been associated with increase cardiovascular mortality, due to a higher prevalence of traditional cardiovascular risk factors and premature atherosclerosis, as a consequence of its systemic inflammation.	24128349
Inflammation, Epilepsy	Altered Intercellular Communication	Inflammation and iron metabolism in adult patients with epilepsy: does a link exist?	24128993
Inflammation, Epilepsy	Altered Intercellular Communication	Inflammation has been shown to play a key role in epilepsy, and may also affect both the iron status and metabolism.	24128993
Seizures, Inflammation, Epilepsy	Altered Intercellular Communication	Our findings demonstrate a relevant relationship between epilepsy and systemic inflammation, with a consistent link between seizures, inflammatory cytokines (IL-6 and TNF-a) and iron regulation and metabolism, as acute phase and antioxidant markers.	24128993
Tuberculosis of other urinary organs, Cancer of Urinary Tract, Urinary tract obstruction, Acute and chronic inflammation	Altered Intercellular Communication	Urinary tuberculosis (UTB) can cause chronic urinary tract inflammation, lead to obstructive uropathy, and potentially contribute to the development of urinary tract cancer.	24129236
Inflammation, Neoplasms	Altered Intercellular Communication	This multiple-receptor inhibition may explain why the peptide was also seen to be a powerful inhibitor of tumour growth and also a partial inhibitor of arthritic joint inflammation in vivo.	24129822
Inflammation, Obesity	Altered Intercellular Communication	During obesity, chronic inflammation of human white adipose tissue (WAT) is associated with metabolic and vascular alterations.	24130331
Inflammation, Morbid obesity	Altered Intercellular Communication	Therapeutic options targeting EC inflammation could prevent adipocyte alterations that contribute to obesity comorbidities.	24130331
Inflammation	Altered Intercellular Communication	Haptoglobin (Hp) is an acute phase protein, the synthesis of which is increased during inflammation.	24130793
Hepatocarcinogenesis, Hepatitis C, Hepatitis B, Chronic, Immune-mediated	Altered Intercellular Communication	Mechanisms of hepatic carcinogenesis in chronic hepatitis B and hepatitis C are incompletely defined but often assumed to be similar and related to immune-mediated inflammation.	24130799
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Loss of ANXA1 expression may support inflammation during IBD and can serve as a biomarker of disease progression.	24130820
Gastroesophageal reflux disease, Pharyngitis, Gorontalo Language	Altered Intercellular Communication	The more modern terms, globus sensation or globus pharyngeus, reflect recognition of one or more possible contributing anatomico-physiological factors, such as gastro-oesophageal reflux disease (GORD) or pharyngeal inflammation.	24130967
Inflammation, Disorders of Porphyrin Metabolism, Arthropathy	Altered Intercellular Communication	Chronic inflammation related to this patient's seronegative arthropathy, although atypical for porphyria, might have contributed to the development of AA amyloidosis.	24131077
Inflammation, Congestive heart failure	Altered Intercellular Communication	Inflammation is part of the pathophysiology of congestive heart failure (CHF).	24131549
Inflammation	Altered Intercellular Communication	In EHOA patients ANCA and anti-CCP antibodies might be either markers of inflammation involving neutrophils and/or markers of an underlying autoimmune process.	24131910
Inflammation, Calcinosis	Altered Intercellular Communication	Calcinosis has been associated with inflammation but information about its pathogeny continues to evolve as we learn more about the underlying processes.	24131911
Communicable Diseases, Inflammation	Altered Intercellular Communication	Although markers of inflammation and insulin resistance are also related to the onset of surgical infection, leptin correlates more closely with the risk of infection than does any other factor.	24132530
Barrett Esophagus, Carcinoma, Adenocarcinoma Of Esophagus	Altered Intercellular Communication	Esophageal adenocarcinoma (EAC) may develop through a process involving inflammation [reflux esophagitis (RE)] leading to metaplasia [Barrett's esophagus (BE)] and carcinoma.	24132576
Inflammation, Tissue injury	Altered Intercellular Communication	These data suggest a role for gut mucosal macrophages in HIV immune pathogenesis: infiltrated macrophages in the intestinal mucosa may promote local inflammation and tissue injury, whereas their low phagocytic activity prevents the efficient elimination of luminal antigens that cross the damaged intestinal barrier.	24133185
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	We suggest that eosinophilic inflammation may be involved in the pathogenesis of PVC-induced OA and that FeNO monitoring can be used for its diagnosis.	24133363
Crohn Disease, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Metastatic Crohn's disease (CD) is an extremely rare extragastrointestinal manifestation of CD, and is characterized histopathologically by the presence of non-caseating granulomatous inflammation.	24133609
Granulomatous inflammation, Swelling, gastrointestinal	Altered Intercellular Communication	However, a few cases of genital swelling associated with granulomatous inflammation prior to a diagnosis of gastrointestinal CD have been documented.	24133609
Inflammation	Altered Intercellular Communication	Abnormalities of liver function tests in Kawasaki disease patients may occur as a result of inflammation of both the biliary and portal systems.	24134764
Inflammation, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Comparing the highest with the lowest quintiles of dietary fiber intake, adjusted predicted marginal risk ratios (95% confidence interval) for the metabolic syndrome, inflammation, and obesity were 0.78 (0.69-0.88), 0.66 (0.61-0.72), and 0.77 (0.71-0.84), respectively.	24135514
Noninfiltrating Intraductal Carcinoma	Altered Intercellular Communication	Despite an evident lack of power, this study elicited neuroregulin 1, a vasoreactivity-, inflammation- and angiogenesis-related gene, as a possible candidate predictor of DCI.	24135536
Communicable Diseases, Inflammation, Bronchiectasis	Altered Intercellular Communication	In immunocompetent patients with bronchiectasis, key clinico-pathophysiological relationships exist between exacerbation frequency, lung function, health-status, infection and inflammation.	24136152
Inflammation, Bronchiectasis	Altered Intercellular Communication	It is also not known how local and systemic inflammation in PAD compares with that in immunocompetent (non-PAD) bronchiectasis patients.	24136152
Communicable Diseases, Inflammation, Bronchiectasis	Altered Intercellular Communication	We assessed symptoms, exacerbation frequency, health-status, lung function, CT, airway and systemic inflammation and infection in 33 PAD patients and 20 immunocompetent controls with bronchiectasis.	24136152
Inflammation	Altered Intercellular Communication	Despite less severe airflow obstruction, PAD patients had similar health-status impairment and greater airway (sputum log10 IL-6 2.71 vs. 1.81 pg/ml, p = 0.001) and greater systemic inflammation than immunocompetent bronchiectasis controls (serum log10 CRP 0.77 vs. 0.36 mg/l, p = 0.001).	24136152
Inflammation, Bronchiectasis	Altered Intercellular Communication	Finally, patients with PAD had greater airway and systemic inflammation than a control population with non-PAD bronchiectasis which may suggest a dysregulated airway immune response.	24136152
Inflammation, Asthma	Altered Intercellular Communication	NLRP3 inflammasome is upregulated in neutrophilic asthma and may regulate the inflammation process observed in this asthma phenotype through production of IL-1b.	24136334
Inflammation, Lymphoma, Neoplasms	Altered Intercellular Communication	Other changes were for lymphoma vs inflammation or lymphoma typing (n = 89) and for confirmation of or change in tumor type for benign (n = 36) or malignant (n = 69) tumors.	24136579
Steatohepatitis, Inflammation, Metabolic Syndrome X, Prehypertension	Altered Intercellular Communication	Prehypertension is associated with an increased prevalence of metabolic syndrome, hepatic steatosis and subclinical inflammation.	24136756
Inflammation, Eosinophilic granulomatosis with polyangiitis, Vasculitis, CTCAE	Altered Intercellular Communication	Churg-Strauss syndrome (CSS) is an anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis; it is extremely rare in childhood and defined according to the Chapel-Hill Consensus as an eosinophil-rich and granulomatous inflammation involving the respiratory tract and necrotizing vasculitis affecting small to medium-sized vessels.	24136903
Inflammation, Hypertension, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	CVD risk factor prevalence at follow-up ranged from 5.5% (diabetes) to 26.4% (hypertension) and 31.3% (inflammation); risk differed across BMI trajectories.	24136924
Inflammation, Psoriasis, Cardiovascular Diseases	Altered Intercellular Communication	Risk factors for cardiovascular disease in psoriasis: relation to inflammation assessed by the severity and duration of illness.	24138074
Inflammation, Psoriasis	Altered Intercellular Communication	To evaluate the epidemiological profile of patients with psoriasis, focusing on the risk factors for CVDs and inflammation.	24138074
Inflammation, HIV Infections	Altered Intercellular Communication	Systemic effects of inflammation on health during chronic HIV infection.	24138880
Inflammation, HIV Infections	Altered Intercellular Communication	Many markers of inflammation are elevated in HIV disease and strongly predictive of the risk of morbidity and mortality.	24138880
Inflammation	Altered Intercellular Communication	A conceptual model has emerged to explain this syndrome of diseases where HIV-mediated destruction of gut mucosa leads to local and systemic inflammation.	24138880
Inflammation	Altered Intercellular Communication	The combined effect of systemic inflammation and excess clotting on tissue function leads to end-organ disease.	24138880
Inflammation, HIV Infections, Chronic inflammatory disorder	Altered Intercellular Communication	It is likely that knowledge gained on how inflammation affects health in HIV disease could have implications for our understanding of other chronic inflammatory diseases and the biology of aging.	24138880
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Evidence is accumulating that chronic inflammation may have an important mechanism for the development and progression of lung cancer.	24139238
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Future studies involving larger control and case populations will undoubtedly lead to a more thorough understanding of the role of the polymorphisms involved in the inflammation pathway in lung cancer.	24139238
Scab, Earache, Hearing Loss, Partial, Inflammation	Altered Intercellular Communication	Itching, otalgia, and hypoacusis were the symptoms reported by the patients and the apparent signs were debris in the ear, scabs and inflammation of the external auditory meatus.	24139621
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor a (TNFa) plays a key role in orchestrating the complex events involved in inflammation and immunity.	24139907
Inflammation, Fatty Liver Disease	Altered Intercellular Communication	Despite similar circulating irisin levels between NAFL and NASH groups, irisin may be independently and positively associated with the presence of portal inflammation.	24140091
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Biomarkers of neurohormonal stimulation, inflammation, and endothelial dysfunction were measured.	24140097
Inflammation, Refractory anemias, Spinal stenosis of lumbar region, Facet joint arthrosis, Spondylitis	Altered Intercellular Communication	Lumbar canal stenosis in RA is caused not only by degeneration but also by RA-related spondylitis, which includes facet arthritis and inflammation around the vertebral endplate.	24140780
Inflammation	Altered Intercellular Communication	The etiology of this condition is not well understood; however, it is a form of chronic irritation and inflammation.	24141102
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	A lymphocyte association with incident diabetes, which was the strongest association among the major white cell types, was partially explained by insulin sensitivity rather than subclinical inflammation.	24141640
Inflammation, Nasal Polyps, Common Cold, Allergic	Altered Intercellular Communication	Although polyps seem to be a manifestation of chronic inflammation of nasal/paranasal sinus mucosa in both allergic and non-allergic subjects, the pathogenesis of nasal polyposis remains unknown.	24141678
Aggressive course, Inflammation, Hypoxia	Altered Intercellular Communication	Some extremely aggressive cancers are also associated with hypoxia, inflammation and high leukocyte infiltration.	24141779
Cessation of life, Inflammation	Altered Intercellular Communication	Brain death induces inflammation evidenced by the up-regulation of TNF in serum and pancreatic tissue.	24142035
Inflammation, Gall Bladder Diseases	Altered Intercellular Communication	Among them, 105 patients with uncomplicated gallbladder disease (no inflammation or no clinical symptoms) and another 105 patients who underwent CLC were selected for this study.	24142653
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Several inflammation biomarkers have been implicated in the pathogenesis and prognosis of acute coronary syndromes.	24142685
Photoreceptor degeneration, Atrophic condition of skin, Retinitis	Altered Intercellular Communication	CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice.	24142887
methyldopa, Inflammation, Nerve Degeneration	Altered Intercellular Communication	CCL2/CCR2 inhibition might represent a powerful tool for controlling inflammation and neurodegeneration in AMD.	24142887
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	TGF-b1 signal pathway in the regulation of inflammation in patients with atrial fibrillation.	24144036
Fibrillation, Atrial Fibrillation, Inflammation	Altered Intercellular Communication	AF is associated with inflammation, and the inflammation is also involved in the fibrillation and sustain of AF.	24144036
Granulomatous inflammation, Unspecified visual loss	Altered Intercellular Communication	The morphological similarity and the anatomical continuity between the meningeal and the perioptic tissues suggest that extension of granulomatous inflammation along such tissue planes accounted for visual loss in these two patients with WG.	24144064
Inflammation, Nasal Polyps, Granulomatosis, Eosinophilic granulomatosis with polyangiitis, Mononeuritis, Asthma, Hypereosinophilia, Systemic Vasculitis	Altered Intercellular Communication	However, on the basis of the past medical history of nasal polyposis, asthma, and hypereosynophilia as well as of further investigations (biopsy of the nasal mucosa showing granulomatous inflammation with a rich eosinophilic infiltrate, electromyography demonstrating, mononeuritis multiplex and positive p-ANCA), eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss syndrome, was diagnosed.	24144341
Inflammation, Demyelination, Trauma, Nervous System, Axonal degeneration, nervous system disorder	Altered Intercellular Communication	Multiple sclerosis (MS) is a neurological disease characterised by central nervous system inflammation, demyelination, axonal degeneration and neuronal injury.	24144874
Coronary Artery Disease	Altered Intercellular Communication	Coronary artery disease (CAD), as a lipid-driven and inflammation-driven disease, has threatened thousands of patients' lives.	24146036
Inflammation, Necrosis	Altered Intercellular Communication	The markers were associated with poor histologic type, high grade, necrosis, HR negativity, inflammation, and p53 expression (vessel size only).	24146798
HIV-1	Altered Intercellular Communication	Thus, IDO-induced immune-metabolism may be considered as a new inflammation-related marker for HIV-1 disease progression.	24147117
Inflammation, Atherosclerosis	Altered Intercellular Communication	However, there were no significant changes at T12 between groups N and H following rosuvastatin intake in group H. In conclusion, the quantitative analysis with 18F-FDG-PET/CT could be efficient in the localization of the inflammation and evaluation of its progression in atherosclerosis instead of global evaluations with systemic inflammation biomarkers.	24148785
Inflammation, Acute Cerebrovascular Accidents	Altered Intercellular Communication	Our results underline the deleterious role of inflammation in acute stroke patients.	24148838
Inflammation	Altered Intercellular Communication	Subclinical inflammation is detectable with increasing BMI and also WHtR.	24149444
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Elevated CNS inflammation in patients with preclinical Alzheimer's disease.	24149932
Inflammation, Data types - Address	Altered Intercellular Communication	Thus, brain inflammation occurs early at the preclinical stage of AD and may have an important role in pathology.	24149932
Inflammation	Altered Intercellular Communication	Diet of patients after pouch surgery may affect pouch inflammation.	24151365
Inflammation, Diverticulitis, Comorbidity	Altered Intercellular Communication	Data were collected with regard to age, sex, albumin level on admission, left or right inflammation site, the history of recurrent diverticulitis, preoperative comorbidity, smoking habits, medication, treatment policy, morbidity, and mortality.	24151389
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Moderate to severe mucosal inflammation was detected in 60.0% (18/30) of the control group.	24151905
Gastroesophageal reflux disease, Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The etiologies of cardiac inflammation were H. pylori infection and gastroesophageal reflux disease (GERD).	24151905
Helicobacter pylori Negative, Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	For antral H. pylori-negative participants, cardiac mucosal inflammation was correlated with esophageal mucosal inflammation (P < 0.05), while for those with antral H. pylori infection it was associated with antral mucosal inflammation (P < 0.01).	24151905
Inflammation	Altered Intercellular Communication	Normal-appearing cardiac mucosa under endoscopy might present with histopathologically moderate to severe cardiac inflammation.	24151905
Gastroesophageal reflux disease, Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The etiologies of cardiac inflammation were H. pylori infection and GERD.	24151905
Inflammation, Optic Neuropathy, Ischemic	Altered Intercellular Communication	Nerve ischemia due to inflammation and microvasculitis has been suggested as the pathophysiological mechanism for DLRPN.	24152254
Granulomatous inflammation	Altered Intercellular Communication	Histopathological examination revealed granulomatous inflammation in four cases.	24152503
Communicable Diseases, Acute inflammation, Patellofemoral osteoarthritis	Altered Intercellular Communication	Revision surgery was performed in 24/69 (34.8%) patients and confirmed the SPECT/CT diagnosis in 21 patients (seven loosening, one infection, two subchondral fractures, two postoperative inflammation and nine patellofemoral osteoarthritis).	24152807
Central Nervous System	Altered Intercellular Communication	Mycoplasma pneumoniae is associated with a variety of extrapulmonary manifestations, including central nervous system inflammation.	24153008
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) is characterized by local inflammation of the sinonasal tissues.	24153332
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Diet may be associated with the development of type 2 diabetes through its effects on low-grade inflammation.	24153342
Inflammation	Altered Intercellular Communication	A higher ADII was associated with a higher summary score for inflammation [b-adjusted = 0.04 per SD (95% CI: 0.01, 0.07 per SD)].	24153342
Inflammation, physiopathological	Altered Intercellular Communication	These findings confirm that the potential mechanism of AGEs on pancreatic dysfunction involves the induction of inflammation and the suppression of PDX-1 and GLUT2 expression.	24154804
Inflammation, Neoplasms	Altered Intercellular Communication	High CLR density associated with better survival and had prognostic value that was independent of stage, Klintrup-Makinen score for peritumoral inflammation and the numbers of tumor infiltrating T cells.	24154855
Neurogenic Inflammation	Altered Intercellular Communication	PET-scan shows peripherally increased neurokinin 1 receptor availability in chronic tennis elbow: visualizing neurogenic inflammation?	24155873
Pain Distress Question, Neurogenic Inflammation	Altered Intercellular Communication	The NK1 receptor and its primary agonist, substance P, also play a crucial role in peripheral tissue in response to pain, as part of neurogenic inflammation.	24155873
Inflammation	Altered Intercellular Communication	The increased NK1 receptor availability is interpreted as part of ongoing neurogenic inflammation and may have correlation to the pathogenesis of chronic tennis elbow.	24155873
Inflammation, Hypereosinophilia	Altered Intercellular Communication	Skin biopsy revealed dermal inflammation with presence of hypereosinophilia, thereby confirming ACHSS.	24156229
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	The Alzheimer's disease "inflammation hypothesis" has emerged only recently, suggesting the risk of developing AD might be influenced by variants of genes encoding for inflammatory mediators.	24156267
Sepsis, Inflammation, Respiratory Distress Syndrome, Adult	Altered Intercellular Communication	Biomarkers of lung epithelial injury and inflammation distinguish severe sepsis patients with acute respiratory distress syndrome.	24156650
Inflammation, Endothelium	Altered Intercellular Communication	A panel that included 11 biomarkers of inflammation, fibroblast activation, proteolytic injury, endothelial injury, and lung epithelial injury was measured in plasma from the morning of ICU day two.	24156650
Inflammation, Hypothyroidism	Altered Intercellular Communication	FT3 also had a moderate negative correlation with CRP (r = -0.475, P < 0.001), which might indicate that hypothyroidism may activate the inflammation response.	24157158
Inflammation, Metabolic Syndrome X, MS gene	Altered Intercellular Communication	Metabolic syndrome (MS) is suggested to be associated with a low grade inflammation state, but the relationship between inflammation biomarkers and the components of metabolic syndrome in adolescents are still lacking.	24160219
Inflammation, Metabolic Diseases	Altered Intercellular Communication	The association found between individual components of MS and CRP concentrations suggests that inflammation might be an early event in the development of metabolic disorders in adolescents.	24160219
Chronicity, Inflammation	Altered Intercellular Communication	Conicity index as a contributor marker of inflammation in haemodialysis patients.	24160234
HD Term Type, Inflammation	Altered Intercellular Communication	Abdominal fat mass is an important risk factor of inflammation in the general population as it is in haemodialysis (HD) patients.	24160234
HD Term Type, Inflammation	Altered Intercellular Communication	Results support the hypothesis that inflammation in HD patients has pleiotropic effects depending on abdominal body adiposity.	24160234
Acute inflammation	Altered Intercellular Communication	Efficacy and safety of intracameral triamcinolone acetonide to control postoperative inflammation after phacotrabeculectomy.	24160382
Inflammation, Inflammatory disorder	Altered Intercellular Communication	The aim of the present study was to test the hypothesis that inflammation affects the expression of Fe-related proteins in the duodenum and monocytes of patients with chronic inflammatory disorders, thus contributing to dysregulated Fe homeostasis.	24160450
methyldopa, Inflammation	Altered Intercellular Communication	Apoptosis and inflammation play important roles in AMD pathogenesis.	24160756
Scleral Diseases, Orbital Pseudotumor	Altered Intercellular Communication	Immunoglobulin G4-related sclerosing disease with orbital inflammation in a 12-year-old girl.	24160980
Scleral Diseases, Orbital Pseudotumor	Altered Intercellular Communication	Immunoglobulin G4-related sclerosing disease is a rare but potentially debilitating cause of orbital inflammation, with a predilection for older males.	24160980
Inflammation	Altered Intercellular Communication	N-terminal pro-brain natriuretic peptide levels were found to be a valuable determinant in indicating cardiac inflammation and haemodynamics.	24161016
Inflammation	Altered Intercellular Communication	Studies have indicated that human CAVD tissues are infiltrated by lipids and that inflammation may play a role in the pathobiology.	24161325
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Here, MnSOD mRNA negatively correlates with steatosis grade but not with extent of fibrosis or inflammation.	24161595
Inflammation, EIU	Altered Intercellular Communication	The LPLA2 activity in rat AH was significantly increased by EIU induction, and was correlated to the extent of inflammation in the AC.	24161624
Inflammation	Altered Intercellular Communication	These results demonstrate that the LPLA2 activity in the AH is augmented with the inflammation in the AC and suggest that the LPLA2 in the AH participates in the inflammation process in the AC.	24161624
myocardial injury	Altered Intercellular Communication	Loss of ACE2 exacerbates AngII-mediated inflammation, myocardial injury and dysfunction in ACE2-deficient hearts via activation of the CTGF-FKN-ERK and MMP signaling.	24161906
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Hypertension impairs left ventricular (LV) diastolic and systolic function, which might be aggravated by inflammation or neurohumoral activation.	24162729
Inflammation, Hypersensitivity	Altered Intercellular Communication	CoCr-EES showed a lower inflammation score (with no hypersensitivity) and less fibrin deposition versus SES and PES.	24163064
Inflammation, Thrombosis	Altered Intercellular Communication	CoCr-EES demonstrated greater strut coverage with less inflammation, less fibrin deposition, and less late and very late stent thrombosis compared with SES and PES in human autopsy analysis.	24163064
Hepatic Metabolism, Fibrosis Assessment, Acute inflammation	Altered Intercellular Communication	We hypothesize that presence of fibrosis, reduction of active inflammation, and decreased hepatic metabolism and function are potential causes of the lower FDG uptake in cirrhotic livers.	24163174
Inflammation, Peritonitis	Altered Intercellular Communication	As neutrophils treated with DAPKi also showed reduced recruitment to the site of inflammation in a mouse peritonitis model, DAPK2 may be a novel target for anti-inflammatory therapies.	24163421
Inflammatory, Inflammation, Inflammatory disorder	Altered Intercellular Communication	Recently, the increased knowledge in the field of auto inflammation highlighted shared immune mechanisms in the pathogenesis of both classical monogenetic and multifactorial auto inflammatory diseases and a broad spectrum of chronic age-related inflammatory pathologies.	24164192
Inflammation, Inflammatory disorder	Altered Intercellular Communication	In the light of these considerations, we propose an update of auto inflammatory diseases and a new interpretation of auto inflammation with both theoretical and clinical implications.	24164192
Communicable Diseases, Inflammation	Altered Intercellular Communication	Surgical site inflammation and infection were graded based on degree of inflammation, discharge, wound culture, and blood culture.	24164587
Communicable Diseases, Inflammation	Altered Intercellular Communication	Fifty-eight patients developed surgical site inflammation and infection.	24164587
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Multivariate logistic regression analysis showed that risk factors for significant CAD included age, diabetes, smoking and inflammation, whereas high serum Klotho values were associated with a lower risk for CAD.	24165855
Inflammation, Obesity	Altered Intercellular Communication	A meal replacement may be an effective strategy in the management of obesity to increase antioxidant intake, attenuating oxidative stress and inflammation.	24166510
Gastrointestinal inflammation	Altered Intercellular Communication	Patients with intestinal inflammation (n=20) had higher BMI SDS than those without, p=0.007.	24167070
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Multivariate path analysis of serum 25-hydroxyvitamin D concentration, inflammation, and risk of type 2 diabetes mellitus.	24167365
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Inflammation plays a crucial role in the development and progression of osteoarthritis (OA).	24167367
Sinusitis	Altered Intercellular Communication	Chronic sinusitis can be caused by many different diseases that share chronic inflammation of the sinuses as a common symptom.	24167940
Inflammation	Altered Intercellular Communication	Few studies have examined the association of nonexercise physical activity with markers of inflammation and oxidative stress.	24168102
Inflammation	Altered Intercellular Communication	Daily nonexercise physical activity is associated with lower levels of systemic inflammation.	24168102
Inflammation	Altered Intercellular Communication	There was no occurrence of systemic reaction, local inflammation or exudation.Wounds were healed at Phase I.	24169289
Inflammation, Carcinoma	Altered Intercellular Communication	Inflammation as a validated prognostic determinant in carcinoma of unknown primary site.	24169348
Malignant Neoplasms	Altered Intercellular Communication	Inflammation-based prognostic systems are stage-independent prognostic predictors in various malignancies.	24169348
Necrotizing granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	Tuberculosis was diagnosed by presence of acid fast bacilli in sputum smears, positive culture for Mycobacterium tuberculosis or demonstration of chronic caseating granulomatous inflammation in tissue specimens.	24169384
Inflammation	Altered Intercellular Communication	The histology showed a granulomatous inflammation of the epiglottis.	24169483
Tumor necrosis, Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Disturbed tumor necrosis factor system is linked with lower eGFR and chronic inflammation in hypertension.	24170558
Inflammation, Haiti	Altered Intercellular Communication	HT showed higher rates of insulin resistance and enhanced chronic inflammation compared with NT.	24170558
Renal Insufficiency, Inflammation, Haiti	Altered Intercellular Communication	Regression analysis indicated that the TNF-related parameters were closely linked with mild renal dysfunction both in NT and HT, and moderately related to chronic inflammation only in HT.	24170558
Inflammation, Haiti	Altered Intercellular Communication	These results suggest that the disturbed TNF system is closely linked with chronic inflammation rather than with insulin resistance in HT.	24170558
Inflammation, Metabolic Syndrome X, PPP1R12A gene, Depression, CTCAE, Somatic, Cardiovascular system	Altered Intercellular Communication	To investigate the association between depression, metabolic syndrome (MBS), somatic, particularly cardiovascular comorbidity, and low-grade chronic inflammation assessed using C-reactive protein (CRP).	24170724
Inflammation, Metabolic Syndrome X, Dirty Bombs, Depression, CTCAE, Comorbidity	Altered Intercellular Communication	We found some intriguing links between stress, depression, metabolic syndrome, and low grade inflammation, which may be relevant for the prevalence of somatic comorbidity in patients with RDD, but further studies are needed to confirm our results.	24170724
Hypercalcemia, Lupus Erythematosus, Systemic	Altered Intercellular Communication	On follow-up, the faster increase in FGF23 than in parathyroid hormone suggested that FGF23 might be involved in the pathogenesis of hypercalcaemia in SLE.	24171337
Laryngitis, Hoarseness	Altered Intercellular Communication	Objective detection of esophagopharyngeal reflux in patients with hoarseness and endoscopic signs of laryngeal inflammation.	24172180
Inflammation, Fibrosis Assessment, Acute respiratory failure	Altered Intercellular Communication	The activins A and B, members of the Transforming Growth Factor b family of proteins, and their binding protein, follistatin, have recently been shown to be important regulators of inflammation and fibrosis but no substantial data are available concerning their roles in ARF.	24172607
Inflammation, Neoplasms	Altered Intercellular Communication	Inflammation is a critical component of tumor progression.	24175807
Communicable Diseases, Inflammation, Irritation - emotion, Malignant Neoplasms	Altered Intercellular Communication	Many cancers arise from sites of infection, chronic irritation, and inflammation.	24175807
Inflammation, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	Increasing evidence correlates the presence of systemic inflammation with poor survival in patients with hepatocellular carcinoma (HCC).	24175853
Inflammation, Cardiovascular finding	Altered Intercellular Communication	Perioperative cardiovascular system failure in South Asians undergoing cardiopulmonary bypass is associated with prolonged inflammation and increased Toll-like receptor signaling in inflammatory monocytes.	24176205
Orbital Pseudotumor	Altered Intercellular Communication	Trochleitis is an unusual form of orbital inflammation localized to the superior oblique tendon and trochlea complex.	24176730
Rheumatoid Arthritis, Juvenile rheumatoid arthritis, Lupus Erythematosus	Altered Intercellular Communication	It has been associated with a number of systemic inflammatory conditions including systemic lupus erythematous, rheumatoid arthritis, and juvenile idiopathic arthritis.	24176730
Degenerative polyarthritis, Inflammation, Metabolic Diseases	Altered Intercellular Communication	Chronic low-grade inflammation is a feature shared by osteoarthritis and metabolic disorders and may contribute to the genesis of both.	24176735
MS gene, Inflammation, Demyelination, Neuronal loss in central nervous system	Altered Intercellular Communication	A substantial proportion of cases with secondary progressive multiple sclerosis have extensive inflammation in the leptomeninges that is associated with increased subpial demyelination, neuronal loss and an exacerbated disease course.	24176976
Musculoskeletal, Shoulder Injuries	Altered Intercellular Communication	F-FDG-PET/CT may be useful for the screening of musculoskeletal inflammation and injury of the shoulder region.	24177044
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) is the persistent inflammation of the sinus and nasal passages lasting over 3 months.	24177790
Malabsorption Syndrome, Gastrointestinal Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Cystic fibrosis gastrointestinal disease includes nutrient malabsorption and intestinal inflammation.	24178246
Malabsorption Syndrome, Fibrosis Assessment, Inflammation, Gastrointestinal dysfunction	Altered Intercellular Communication	We show that the abundances of Escherichia coli in fecal microbiota were significantly higher in young children with cystic fibrosis than in controls and correlated with fecal measures of nutrient malabsorption and inflammation, suggesting that E. coli could contribute to cystic fibrosis gastrointestinal dysfunction.	24178246
Overweight, atherosclerotic	Altered Intercellular Communication	We conducted a prospective study to evaluate the impact of overweight on atherosclerotic events (AE) in dialysis patients with special respect to the malnutrition/inflammation complex syndrome (MICS).	24179012
atherosclerotic	Altered Intercellular Communication	Furthermore, it appears to reflect aspects of atherosclerotic inflammation distinct from hsCRP concentration and may offer incremental information regarding cardiovascular risk.	24179183
Inflammation	Altered Intercellular Communication	In particular, the signal for serum IL-18 located on chromosome two is novel and potentially important in inflammasome triggered chronic activation of inflammation in older adults.	24182552
Inflammation, Diabetes Mellitus, Bipolar Disorder	Altered Intercellular Communication	Diabetes, depressive symptoms, and inflammation in older adults: results from the Health, Aging, and Body Composition Study.	24182629
Inflammation, Bipolar Disorder	Altered Intercellular Communication	This study examined the association between inflammation and both T2DM and elevated depressive symptoms.	24182629
Inflammation, Bipolar Disorder	Altered Intercellular Communication	These findings provide evidence that inflammation is associated with T2DM and elevated depressive symptoms.	24182629
Inflammation	Altered Intercellular Communication	Systemic low graded inflammation has been identified as a possible biological pathway in late-life depression.	24182633
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	EBV-encoded small RNA1 and nonresolving inflammation in rheumatoid arthritis.	24183354
Inflammation, Numerous, Refractory anemias, Autoimmune Diseases, Rheumatoid Arthritis	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by perpetuated inflammation in multiple joints.	24183354
Refractory anemias, Inflammation	Altered Intercellular Communication	To date, there is no cure for RA, and the causal factor for non-resolving inflammation in RA remains unclear.	24183354
Inflammation	Altered Intercellular Communication	In this study, we initially observed expression of Epstein-Barr virus-encoded small RNA1 (EBER1) in the synovial tissue of all five patients who showed nonresolving RA inflammation.	24183354
Degenerative polyarthritis	Altered Intercellular Communication	To confirm this finding, we conducted a second study on synovial tissue samples taken from 23 patients with nonresolving RA inflammation and 13 patients with OA.	24183354
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	All synovial samples from patients with nonresolving inflammation of RA showed positive expression of EBER1 (23/23, 100%), whereas none of the synovial samples from patients with OA showed expression of EBER1 (0/13, 0%; p < 0.001, by Fisher's exact test).	24183354
Inflammation	Altered Intercellular Communication	Taken together, these data strongly suggest that nonresolving RA inflammation is strongly related to the presence of EBER1, which might be, at least partially, responsible for synovial fibroblast interleukin-6 production.	24183354
Inflammation, Hepatitis B	Altered Intercellular Communication	Hepatitis B virus (HBV) can result in asymptomatic carrier (AsC) state or chronic inflammation of liver, which depends on the host immunity.	24183880
Inflammation, physiopathological, Obesity	Altered Intercellular Communication	the low degree of inflammation in obesity contributes to systemic metabolic dysfunction.	24184299
Aneurysm, Inflammation	Altered Intercellular Communication	Extensive work-up revealed a 3-cm SMA aneurysm (SMAA) with surrounding inflammation.	24184459
Arthralgia, Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain diminished after 3 months, while associations between painful joints and inflammation seem to increase, emphasizing the multifactorial aetiology of pain.	24185107
Inflammation, Primary Biliary Cholangitis	Altered Intercellular Communication	Chemokine-chemokine receptor CCL2-CCR2 and CX3CL1-CX3CR1 axis may play a role in the aggravated inflammation in primary biliary cirrhosis.	24185682
Inflammation, Bile duct structure, Primary Biliary Cholangitis	Altered Intercellular Communication	CCL2 and CX3CL1 produced by senescent BECs may promote infiltration of corresponding CCR2 and CX3CR1-expressing cells and further aggravate inflammation in bile duct lesion in PBC.	24185682
Airway structure, ARCN1 gene, Progranulins	Altered Intercellular Communication	Progranulin is a substrate for neutrophil-elastase and proteinase-3 in the airway and its concentration correlates with mediators of airway inflammation in COPD.	24186875
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, GRN wt Allele	Altered Intercellular Communication	Because dysregulated neutrophilic inflammation is implicated in the pathophysiology of chronic obstructive pulmonary disease (COPD), the possible influence of PGRN and digestion products may be of relevance to understanding and treating inflammation in the disease.	24186875
Airway structure, ARCN1 gene, Colonization, GRN wt Allele	Altered Intercellular Communication	The concentration of PGRN relates negatively to the amplified airway inflammation associated with bacterial colonization in clinically stable COPD.	24186875
Inflammation, destruction joint, Synovial Fluid	Altered Intercellular Communication	Our data confirm the evidence that synovial PD activity more accurately reflects active synovial inflammation (which actually causes joint destruction) than do conventional measures in patients treated with MTX.	24187096
Refractory anemias, Pain Distress Question, Inflammation	Altered Intercellular Communication	ChWP is a common feature in RA, more associated with high values for variables related to pain such as the DAS28 and HAQ than to indicators of ongoing inflammation such as swollen joint count, ESR, and CRP.	24187108
Chronic inflammation	Altered Intercellular Communication	Vitamin D receptor mRNA expression levels were significantly upregulated in H. pylori-infected patients and positively correlated with chronic inflammation scores.	24188043
Inflammation	Altered Intercellular Communication	Our results suggest a role of the oral microbiota in the development of inflammation in atherogenesis, particularly of A. actinomycetemcomitans.	24188425
Inflammation, Chronic disease	Altered Intercellular Communication	The relationship between high-sensitivity CRP and polyclonal free light chains as markers of inflammation in chronic disease.	24188493
Fibrosis Assessment, Hepatic inflammation, Fatty degeneration	Altered Intercellular Communication	A univariate analysis showed that the body mass index, platelet count, levels of albumin, aspartate aminotransferase, alanine aminotransferase and g-glutamyl transpeptidase, glucose metabolism, hepatic inflammation, fibrosis and steatosis were associated with elevated AFP levels.	24190142
Proteinuria, Diarrhea, Bothered by Vomiting, Nausea, Treatment-Emergent Adverse Event, Hypertension, CTCAE, Inflammatory disease of mucous membrane, Fatigue	Altered Intercellular Communication	The most common treatment-related treatment-emergent adverse events (all dosing cohorts) were fatigue 60 % (Grade >=3: 10 %), mucosal inflammation 50 %, proteinuria (Grade >=3: 15 %), diarrhea (Grade >=3: 10 %), vomiting (Grade >=3: 5 %), hypertension, and nausea, each 40 %.	24190702
Tissue damage, Inflammation	Altered Intercellular Communication	Crucially, aberrant migration may increase "bystander" tissue damage and heighten inflammation as a result of excess proteinase release during inaccurate chemotaxis, as well as reducing pathogen clearance.	24191150
Inflammation	Altered Intercellular Communication	We show evidence of increased neutrophil proteinase activity in older adults, namely, raised levels of neutrophil proteinase substrate-derived peptides and evidence of primary granule release, associated with increased systemic inflammation.	24191150
Inflammation, Infection	Altered Intercellular Communication	Targeting PI3K signaling may therefore offer a new strategy in improving neutrophil functions during infections and reduce inappropriate inflammation in older patients.	24191150
Inflammatory disorder	Altered Intercellular Communication	sIL-1R2 has potential to be a chemopreventive and/or immunotherapeutic agent in inflammation-related diseases.	24192010
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	High oxidative stress and chronic inflammation can contribute to the pathogenesis of coronary artery disease (CAD).	24192015
Celiac Disease, Gastrointestinal inflammation	Altered Intercellular Communication	Coeliac disease (CD) is a common T cell-mediated disease diagnosed by the presence of gluten-dependent intestinal inflammation and serology.	24192268
Inflammation, Pain Distress Question	Altered Intercellular Communication	Previously, we found that the inflammatory-related transcripts were elevated in growth plate and articular cartilages, indicating that inflammation plays an important role in the chondrocyte disease pathology and may contribute to the overall pain sequelae.	24194321
Inflammation	Altered Intercellular Communication	Important and novel findings were an increase in inflammatory proteins generally starting at P21 and that exercise exacerbates inflammation.	24194321
Inflammation, Tissue injury	Altered Intercellular Communication	In contrast, HIF-2a-deficient murine inflammatory neutrophils displayed increased sensitivity to nitrosative stress induced apoptosis ex vivo and increased neutrophil apoptosis in vivo, resulting in a reduction in neutrophilic inflammation and reduced tissue injury.	24196071
Inflammation	Altered Intercellular Communication	Expression of HIF-2a was temporally dissociated from HIF-1a in vivo and predominated in the resolution phase of inflammation.	24196071
Inflammation, Chronic inflammatory disorder	Altered Intercellular Communication	These data support a critical and selective role for HIF-2a in persistence of neutrophilic inflammation and provide a platform to dissect the therapeutic utility of targeting HIF-2a in chronic inflammatory diseases.	24196071
Inflammation	Altered Intercellular Communication	Whereas FDG PET/CT imaging has been widely used in periprosthetic infection, it cannot discriminate aseptic from septic inflammation.	24196917
Inflammation	Altered Intercellular Communication	It is therefore possible that senescent cells can differentially induce inflammation in the surrounding tissues, depending on the cause of senescence.	24198727
Inflammation, Disorder of eye, Neoplasms, Retinal Detachment, Communicable Diseases, Abnormality of the vasculature	Altered Intercellular Communication	Exudative retinal detachment as subretinal fluid accumulation occurs due to chorioretinal eye disease (inflammation, infection, tumor, vascular abnormalities) and in systemic diseases too.	24199273
Depression, CTCAE, Brain hemorrhage	Altered Intercellular Communication	To explore the relation between plasma neurotransmitters (Glutamic acid, GAA; g-aminobutyric acid, GABA; 5-hydroxytryptamine, 5-HT; and noradrenaline, NE) and depression in acute hemorrhagic stroke.	24199885
Inflammation, Injury of kidney	Altered Intercellular Communication	These positive results with inflammation biomarkers and lifespan studies suggest that the BPP can protect mice against LPS/GalN-induced liver, lung, and kidney injuries and inflammation by blocking oxidative stress and TNF-a production, thus increasing the survival of the toxic shock-induced mice.	24200110
Inflammation, Aneurysm, Infected	Altered Intercellular Communication	Infected aortic aneurysms are diagnosed on the basis of a positive bacterial blood culture, clinical evidence of inflammation, and morphologic findings on computed tomography (CT).	24200128
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Low Level Laser Therapy has already been demonstrated to mitigate amyloid-b peptide induced oxidative stress and inflammation, a key driver of Alzheimer's disease.	24200521
Inflammation	Altered Intercellular Communication	Lipoprotein properties were severely impaired in the AF group with increased extent of oxidation and inflammation.	24201066
Inflammation, Villous, Gastrointestinal symptom	Altered Intercellular Communication	Daily intake and long-term consumption of oats did not result in small-bowel mucosal villous damage, inflammation, or gastrointestinal symptoms.	24201240
Inflammation	Altered Intercellular Communication	Inflammaging is a phenomenon triggered by the conjunction of chronic repetitive and subclinical inflammation from external aggressors and internal inflammatory mechanisms due to the progressive degradation of systems such as the mitochondrial function.	24202618
Inflammation	Altered Intercellular Communication	Inflammaging is a phenomenon triggered by the conjunction of chronic repetitive and subclinical inflammation from external aggressors and internal inflammatory mechanisms due to the progressive degradation of systems such as the mitochondrial function.	24202618
methyldopa, Inflammation	Altered Intercellular Communication	Remarkable correlations have been documented between common or rare immunological/inflammatory gene polymorphisms and AMD, unequivocally indicating the involvement of inflammation and immune-mediated processes (complement activation) in the pathogenesis of this disease.	24202618
Inflammation, Specimen Type - Fistula	Altered Intercellular Communication	Chronic inflammation process will induce longer adhesion area between artery and ureter, which results in unusual fistula site and rigid iliac arteries.	24203347
Inflammation, Cardiac Arrhythmia, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation has recently emerged in the pathogenesis of several cardiovascular disorders, including arrhythmias.	24203349
glycation, Inflammation	Altered Intercellular Communication	The accumulation of advanced glycation end products (AGEs) has been reported to be a major contributor to chronic systemic inflammation.	24206165
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	We aimed to evaluate the presence of metabolic syndrome and to assess the insulin resistance associated with chronic inflammation in patients with PsA.	24206172
Inflammation	Altered Intercellular Communication	Evidence of increased inflammation was demonstrated by an increase in CRP and ESR (P <= 0.05, THR and TKR).	24206644
Inflammation	Altered Intercellular Communication	Elevated troponin I levels but not low grade chronic inflammation is associated with cardiac-specific mortality in stable hemodialysis patients.	24206774
Inflammation, Coronary Arteriosclerosis, myocardial injury	Altered Intercellular Communication	The mechanism for this risk is likely independent of inflammation, but may reflect chronic subclinical myocardial injury or unmask those with subclinical atherosclerotic heart disease.	24206774
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The metabolic syndrome is featured by enhanced low-grade systemic inflammation and oxidative stress.	24209691
Inflammation, Complete atrioventricular block	Altered Intercellular Communication	We investigated whether serum M30-antigen levels might help to characterize the various phases of CHB and predict the state of significant inflammation in patients with CHB.	24210327
Inflammation, Complete atrioventricular block	Altered Intercellular Communication	Serum M30 levels are associated with the presence of significant inflammation, especially in patients with normal or minimally elevated ALT in CHB patients.	24210327
Inflammation, Oculomotor Nerve Paralysis, Neoplasms, Traumatic injury	Altered Intercellular Communication	Common causes for acquired isolated oculomotor nerve palsy in children are trauma, inflammation, and neoplasia.	24210342
Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Systemic inflammation at the development of an acute coronary syndrome (ACS) might alter the high-density lipoprotein (HDL) components and function.	24210679
Inflammation	Altered Intercellular Communication	The ACS1 group showed a marked increase in high-sensitivity C-reactive protein and serum amyloid A, reflecting systemic inflammation.	24210679
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	The typical inflammation signs of the vascular wall demonstrated by the gadolinium-enhanced MRI strengthened the hypothesis of CNS vasculitis.	24211061
Inflammation, Uveitis	Altered Intercellular Communication	Of masquerade syndrome patients, 90% had posterior inflammation, compared with 63% of uveitis patients (P = 0.006).	24211361
Inflammation, Neoplastic masquerade syndrome	Altered Intercellular Communication	Patients with neoplastic masquerade syndromes were more likely to be older, male, or non-African American and to have posterior segment inflammation and unilateral disease.	24211361
Inflammation	Altered Intercellular Communication	Objective impairments correlated significantly with self-reported symptoms (p<0.05) as well as levels of the inflammation marker, C-reactive protein (p=0.001).	24211375
Gastrointestinal inflammation	Altered Intercellular Communication	However, little is known about these cells, their precursors, and their role in intestinal inflammation.	24212097
Airway structure	Altered Intercellular Communication	A few epidemiologic studies have shown elevations in the fraction of exhaled nitric oxide, a marker of airway inflammation, after exposure to traffic-related pollutants.	24213146
Airway structure	Altered Intercellular Communication	We examined whether short-term exposures to ozone (O3), oxides of nitrogen (NOx), or particulate matter <10 mm (PM10) were associated with proximal and distal airway inflammation.	24213146
Airway structure, Inflammation	Altered Intercellular Communication	Exposure to O3 was associated with a marker of distal airway inflammation, while the association was less obvious for inflammation of the proximal airways.	24213146
Sparganosis, Orbital Pseudotumor	Altered Intercellular Communication	Despite its rarity, ocular sparganosis should be considered as a possible cause of orbital inflammation in patients.	24215169
Inflammation, Acute Coronary Syndrome, Blood Vessel, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Long pentraxin 3 (PTX3) is a component of the pentraxin superfamily and a potential marker of vascular damage and inflammation, associated with negative outcome in patients with acute coronary syndromes (ACS).	24215445
Inflammation	Altered Intercellular Communication	Histologically, 24 (89%) of these had little inflammation, and 26 (96%) were negative for H. pylori by immunohistochemistry.	24215601
Inflammation, Spondylitis, Autoimmune Disorder, CTCAE	Altered Intercellular Communication	Ankylosing spondylitis (AS) is an autoimmune disorder characterized by inflammation of the spine and large joints.	24215664
Renal Insufficiency	Altered Intercellular Communication	We recently demonstrated involvement of the inflammatory classical NF-kB pathway in inflammation-induced impairments in muscle OXPHEN.	24215713
ARCN1 gene, Muscle (organ)	Altered Intercellular Communication	We hypothesised that inflammation-induced classical NF-kB activation contributes to loss of muscle OXPHEN in COPD by reducing IKK-a expression.	24215713
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Identification and characterisation of osteoarthritis patients with inflammation derived tissue turnover.	24216059
Degenerative polyarthritis, Arthritis, Degenerative disorder	Altered Intercellular Communication	Osteoarthritis (OA) is a degenerative disease with a subset of patients experiencing joint inflammation, but C-reactive protein (CRP) has shown limited use in OA as a diagnostic marker.	24216059
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	A bigger proportion of patients were elevated in CRPM compared to hsCRP, indicating MMP-derived inflammation as a component of OA.	24216059
Inflammation, Primary malignant neoplasm, Miller Dieker syndrome	Altered Intercellular Communication	Here we report that myeloid-derived suppressor cells (MDSC), which are classically linked to immunosuppression, inflammation, and cancer, were markedly expanded in the bone marrow of MDS patients and played a pathogenetic role in the development of ineffective hematopoiesis.	24216507
Neurogenic Inflammation, Traumatic, Ischemic stroke, Edema	Altered Intercellular Communication	SP has been implicated in the development of neurogenic inflammation and subsequent edema development following both traumatic brain injury and ischemic stroke.	24216617
Inflammation, Calcification of the aorta	Altered Intercellular Communication	Furthermore, FLC k and l levels were positively correlated with inflammation, aortic calcification and the levels of various uremic toxins levels.	24217396
Inflammation, Chronic Kidney Diseases, Vascular calcification	Altered Intercellular Communication	In conclusion, our results indicate that FLC k and l levels are elevated in CKD patients and are associated with inflammation, vascular calcification and levels of other uremic toxins.	24217396
Inflammation	Altered Intercellular Communication	Chronic inflammation has been associated with decreased physical function in the elderly and may also influence physical function in HIV-infected individuals.	24219874
Inflammation, Muscular Dystrophy, Myopathy, Myositis	Altered Intercellular Communication	Muscular dystrophies (MDs) and inflammatory myopathies (IMs) are debilitating skeletal muscle disorders characterized by common pathological events including myodegeneration and inflammation.	24220031
Excessive tearing, Inflammation, Stenosis Morphology	Altered Intercellular Communication	If the wounds are not managed properly, they can lead to scarring, stenosis, and inflammation, which may lead to symptomatic epiphora.	24220405
Inflammation, Irritation, Lacrimal Duct Obstruction, Granuloma	Altered Intercellular Communication	No complications related to the Mini-Monoka tube, such as punctual plug migration, eye irritation, inflammation, granuloma formation, or erosion, occurred during the follow-up period.The goal of reconstructing a lacerated canaliculus is accurate approximation of the injured end of the canaliculus to facilitate mucosal healing and to prevent a canalicular obstruction.	24220405
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Inflammation and immune response may have potential prognostic implications for breast cancer survivors.	24220913
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Acute inflammation status (CRP >= 10 mg/L) may be an important independent biomarker for long-term survival in breast cancer survivors.	24220913
Acute inflammation, Breast Carcinoma	Altered Intercellular Communication	Interventions to decrease circulating CRP concentrations in breast cancer survivors with acute inflammation may improve prognosis.	24220913
Inflammation	Altered Intercellular Communication	Systemic immune defects might reflect severely dysregulated control of chronic inflammation related to disease progression.	24221190
Inflammation	Altered Intercellular Communication	Disease activity was calculated on the basis of clinical and biochemical indices of inflammation (DAS28, ESR, CRP).	24221190
Refractory anemias, Inflammation	Altered Intercellular Communication	Although therapy induced clinical improvement in almost all patients, those with advanced RA remained with signs of inflammation.	24221190
Cessation of life, Inflammation	Altered Intercellular Communication	All three biomarkers of inflammation were associated with an increased risk of macrovascular events and death in analyses adjusted for age, sex, and treatment groups.	24222348
Refractory anemias, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Endothelial dysfunction has been detected in RA patients and seems to be reversed by control of inflammation.	24222719
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Th17 cells, a recently discovered subset of T helper cells that secrete IL-17A, can affect the inflammation process autoimmune and cancer diseases development.	24223764
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	With growing evidence on the role of inflammation in cancer biology, the presence of a systemic inflammatory response has been postulated as having prognostic significance in a wide range of cancer types.	24223776
Inflammation	Altered Intercellular Communication	Valvular calcification, inflammation, and mortality in dialysis patients.	24224425
Down Syndrome, Inflammation	Altered Intercellular Communication	A recent study has found that aerobic training reduced inflammation in obese women with Down syndrome.	24224738
Acute and chronic inflammation	Altered Intercellular Communication	A 3-month detraining period significantly impaired chronic inflammation in obese women with DS.	24224738
Inflammation, Periodontitis	Altered Intercellular Communication	Chronic periodontitis (CP) is a continuous, reversible source of inflammation with a potential impact on mortality in patients undergoing hemodialysis (HD).	24224959
Periodontal Infection, Bronchitis	Altered Intercellular Communication	Individuals with periodontal infection showed, approximately, five times more likelihood to have bronchial inflammation than those without such periodontal tissue infection.	24224961
Periodontitis, Asthma, Bronchitis	Altered Intercellular Communication	The findings demonstrate the influence of periodontitis on severe asthma, given that the frequency of periodontitis is higher in individuals with severe asthma than in those without a diagnosis of bronchial inflammation.	24224961
Intracranial Germinoma, Failure (biologic function)	Altered Intercellular Communication	[Intracranial germinoma masquerading as a granulomatous inflammation, diagnostic failure after brain biopsy].	24225569
Granulomatous inflammation, Pineal germinoma	Altered Intercellular Communication	We concluded that the possibility of germinoma should be considered in case granulomatous inflammation is observed in brain biopsy specimens.	24225569
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	And human medical evidence suggests a net aggravation of cancer risk from the sequestration of telomerase, because cells with short telomeres are at high risk of neoplastic transformation, and they also secrete cytokines that exacerbate inflammation globally.	24228928
Inflammation, Carcinoid Tumor, Parasitic Diseases, Taenia Saginata, Diverticulitis, Endometriosis	Altered Intercellular Communication	In the 88 specimens with unusual pathology, fibrous obliteration was observed in 57 specimens, carcinoid tumor in 11, Encheliophis vermicularis parasite infection in 8, granulatomous inflammation in 6, appendiceal endometriosis in 2, and 1 specimen each showed mucocele, eosinophilic infiltration, Taenia saginata parasite infection, and appendicular diverticulitis.	24229023
Inflammation, Delayed Hypersensitivity	Altered Intercellular Communication	Delayed-type hypersensitivity is induced by induction of inflammation via IL-1, TNF-a and IL-6.	24229039
Inflammation, Asthma	Altered Intercellular Communication	Systemic inflammation in asthma plays a significant role in the development of other diseases.	24229680
Hyperglycemia, Inflammation	Altered Intercellular Communication	These results suggest that high consumption of rice and noodles may contribute to hyperglycaemia through greater insulin resistance and that this relationship is independent of adiposity and systemic inflammation.	24229726
Arteritis, Diabetes Mellitus	Altered Intercellular Communication	Pioglitazone decreases coronary artery inflammation in impaired glucose tolerance and diabetes mellitus: evaluation by FDG-PET/CT imaging.	24229770
vascular inflammations	Altered Intercellular Communication	Recent studies have shown that FDG-PET combined with CT is a reliable tool to visualize and quantify vascular inflammation.	24229770
Demographics Domain, Electrocardiogram: myocardial infarction (finding), Coronary Arteriosclerosis, Arteritis, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Although pioglitazone significantly prevented the progression of coronary atherosclerosis and reduced the recurrence of myocardial infarction in patients with type 2 diabetes mellitus (DM), it remains unclear whether pioglitazone could attenuate coronary artery inflammation.	24229770
Inflammation	Altered Intercellular Communication	Our study indicated that pioglitazone attenuated left main trunk inflammation in patients with impaired glucose tolerance or DM in a glucose-lowering independent manner, suggesting that pioglitazone may protect against cardiac events in patients with impaired glucose tolerance or DM by suppressing coronary inflammation.	24229770
Inflammation	Altered Intercellular Communication	Nuclear factor-kB (NF-kB) regulates cellular responses to inflammation and aging, and alterations in NF-kB signaling underlie the pathogenesis of multiple human diseases.	24231355
vascular inflammations	Altered Intercellular Communication	HDF decreases uraemic toxins, vascular inflammation, and is associated with subsequent improvement in eNOS functionality.	24235073
Chronic Kidney Diseases	Altered Intercellular Communication	The inflammation-lipocalin 2 axis may contribute to the development of chronic kidney disease.	24235082
Inflammation, Chronic Kidney Diseases, Coronary heart disease	Altered Intercellular Communication	Chronic kidney disease (CKD) is an important risk factor for coronary heart disease, and previous studies indicated the involvement of low-grade inflammation in the pathogenesis of CKD.	24235082
Inflammation, Renal function, Chronic Kidney Diseases	Altered Intercellular Communication	Since an activated TNF system, as demonstrated by elevated sTNF-R2, and elevated uric acid were recently implicated in an elevated CKD risk, we conclude that inflammation could play an important role in the pathogenesis of CKD, and that lipocalin 2 is a potential universal marker for impaired kidney function.	24235082
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Reduced nasal nitric oxide production in cystic fibrosis patients with elevated systemic inflammation markers.	24236100
Inflammation	Altered Intercellular Communication	Interventions aimed at reducing chronic inflammation and immune activation in aging, HIV-infected patients may improve their response to vaccines.	24236161
Keratoconjunctivitis, Vernal, Inflammation, Chronic disease	Altered Intercellular Communication	Vernal keratoconjunctivitis (VKC) is a chronic disease affecting conjunctiva even though the immunopathogenetic mechanisms underlying this inflammation are unclear.	24236762
Inflammation	Altered Intercellular Communication	Our study gives a support to the definition of VKC as a systemic inflammation in which HMGB1 and its soluble receptors could play a role.	24236762
Inflammation, Hyperhomocysteinemia	Altered Intercellular Communication	Patients with hyperhomocysteinemia have increased risk for cardiovascular events that potentially involve enhanced inflammation.	24236948
Exfoliative cheilitis	Altered Intercellular Communication	Exfoliative cheilitis (EC) is a rare inflammatory condition affecting the vermilion of the lips and characterized by production of a thick keratin scale.	24237731
Inflammation, Asthma, MS4A2 wt Allele	Altered Intercellular Communication	The fraction of exhaled nitric oxide (FeNO) has been suggested as a non-invasive marker of eosinophilic inflammation in asthma, but lately rather as a biomarker of atopy than of asthma itself.	24237793
Inflammation, Asthma, Bronchiolitis	Altered Intercellular Communication	Asthma after bronchiolitis is common up to early adolescence, but the inflammation and pathophysiology may differ from other phenotypes of childhood asthma.	24237793
Inflammation, Exacerbation	Altered Intercellular Communication	The mechanism by which exacerbations occur remains undefined, however it is likely to be due to virus-induced inflammation.	24237854
Inflammation, Periapical Diseases	Altered Intercellular Communication	MicroRNAs (miRNAs) have been shown to play an important role in the regulation of inflammation and the immune response; however, their role in the pathogenesis of endodontic periapical disease has not been explored.	24238436
Cataract, Intraocular inflammation, Uveitis	Altered Intercellular Communication	To compare the incidence of long-term complications after cataract surgery with primary anterior chamber intraocular lens (AC IOL) implantation in uveitic patients and patients without a history of intraocular inflammation (control group).	24238942
Inflammation	Altered Intercellular Communication	A total of 41 cases was reviewed: periarterial inflammation was shown in 10.3% of patients; 92.9% had clear intima-media plane; and 85.4% had a good outcome.	24239104
Granulomatous inflammation, Tularemia, Necrosis	Altered Intercellular Communication	In particular, if granulomatous inflammation with necrosis is seen histopathologically, tularemia should be excluded before making the diagnosis of TCL.	24239221
Inflammation, neuroborreliosis, niobium	Altered Intercellular Communication	Knowledge of the role of chemokines in the inflammation during neuroborreliosis (NB) is limited.	24239846
Inflammation, Infectious Lung Disorder	Altered Intercellular Communication	Volatile organic compounds (VOCs) in breath may serve as biomarkers of pulmonary infection or inflammation.	24239875
acute diverticulitis, Diverticular Diseases, Colitis	Altered Intercellular Communication	Patients with symptomatic uncomplicated diverticular disease represent a spectrum of patients who report recurrent abdominal symptoms, however are lacking substantial colonic inflammation in contrast to patients with acute diverticulitis.	24240607
Gastrointestinal inflammation, acute diverticulitis	Altered Intercellular Communication	Patients with acute diverticulitis and symptoms suggestive of more severe intestinal inflammation were excluded.	24240607
Nerve Degeneration	Altered Intercellular Communication	Pro-inflammatory S100A9 protein is increasingly recognized as an important contributor to inflammation-related neurodegeneration.	24240735
Vasculitis	Altered Intercellular Communication	We reviewed medical records of 9 consecutive patients with noninfectious ocular or orbital inflammation treated with RTX.	24241484
Inflammation	Altered Intercellular Communication	Low-grade systemic inflammation induced by smoking may represent the link between these 2 conditions.	24244639
ARCN1 gene, Inflammation	Altered Intercellular Communication	Only smokers with COPD seem to have evidence of systemic inflammation.	24244639
Inflammation, Malnutrition, Carcinoma of lung	Altered Intercellular Communication	RDW is associated with several factors that reflect inflammation and malnutrition in lung cancer patients.	24244659
Inflammation	Altered Intercellular Communication	Low-grade systemic inflammation was suggested to participate to the decline of physiological functions and increased vulnerability encountered in older patients.	24244750
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Association between low-grade inflammation and geriatric conditions could be linked to underlying cardiovascular diseases.	24244750
Inflammation, Benign prostatic hypertrophy, Adenocarcinoma of prostate	Altered Intercellular Communication	In the study group, patients with prostatic hyperplasia or inflammation on the prostate biopsy had a significantly better result than in patients with prostatic adenocarcinoma, typically in the changes of Qmax and voided volume (p = 0.012 and p = 0.005, respectively).	24246211
Adenocarcinoma, Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	The changes in Qmax and voided volume after combination treatment were significantly greater in patients with prostatic hyperplasia or inflammation than adenocarcinoma.	24246211
prostatitis	Altered Intercellular Communication	Lower urinary tract symptom improvement after radical prostatectomy correlates with degree of prostatic inflammation.	24246320
prostatitis	Altered Intercellular Communication	To determine if prostatic inflammation at the time of radical prostatectomy (RP) was associated with the International Prostate Symptom Score (IPSS).	24246320
Inflammation	Altered Intercellular Communication	We reviewed pathology slides of those who had a change of 4 points or greater, as measured by the IPSS and correlated inflammation with change in IPSS.	24246320
Inflammation	Altered Intercellular Communication	Multivariate linear regression analyses were performed to determine the association of IPSS with degree of inflammation based on the number of inflammatory cells.	24246320
Inflammation	Altered Intercellular Communication	On univariate analysis, the average improvement in IPSS in patients with severe inflammation was (r = -6.02, 95% confidence interval [CI] -11.0 to -1.1, P = .018) after RP.	24246320
prostatitis	Altered Intercellular Communication	On multivariate analysis, adjusting for age, body mass index (BMI), year of surgery, history of prostatitis, Gleason score, prostate-specific antigen (PSA), prostate weight, and nerve sparing status, only patients with severe prostatic inflammation had significant improvement in their IPSS (r = -5.93, 95% CI -10.81 to -1.04, P = .004).	24246320
prostatitis	Altered Intercellular Communication	Prostatic inflammation measured in prostatectomy specimens is associated with worse baseline IPSS than matched cohorts.	24246320
Inflammation	Altered Intercellular Communication	Specifically, severe inflammation is an independent predictor of IPSS improvement at 1 year after RP.	24246320
Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Diabetes Mellitus, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Given that serum phospholipids (PL) may serve as inflammation mediators, we studied whether they predicted metabolic syndrome (MetS), type-2 diabetes or coronary heart disease (CHD) risk in people prone to enhanced low-grade inflammation.	24246837
Inflammation	Altered Intercellular Communication	This suggests that chronic inflammation and immune system over-activity may underlie the aging process of the human brain, and that potential anti-inflammatory treatments targeting those genes may slow down this process and alleviate its symptoms.	24247109
Inflammation, Chronic Kidney Diseases, Obesity	Altered Intercellular Communication	We hypothesized that the association of central obesity with CKD is modified by the presence of inflammation.	24247217
Inflammation, Obesity	Altered Intercellular Communication	Waist-to-height ratio (WHtR) was used as a central obesity index and C-reactive protein (CRP) was used as an index for inflammation.	24247217
Inflammation, Chronic Kidney Diseases, Obesity	Altered Intercellular Communication	Central obesity is also associated with inflammation and the presence of inflammation modifies the associations of central obesity and CKD.	24247217
Inflammation, Ischemic stroke	Altered Intercellular Communication	Here, the authors assessed this issue, in 48 patients without significant clinical history for major medical illnesses or other factors that promote inflammation, 72 hours after a first-ever acute ischemic stroke.	24247852
Blepharitis, Inflammation, Intermittent exacerbations	Altered Intercellular Communication	is blepharitis, a chronic inflammation of the eyelid margin with intermittent exacerbations, which is very common in ophthalmic practice.	24248163
Rosacea	Altered Intercellular Communication	Rosacea is a chronic inflammatory condition that affects the skin of the face and the eyes.	24248990
Inflammation, CST9 gene	Altered Intercellular Communication	After treatment for CLM with albendazole (800 mg/d for 3 days) and after resolution of perifocal edema and inflammation the typical serpiginous tracks became more obvious.	24249319
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Circulating inflammation markers and prospective risk for lung cancer.	24249745
Inflammation, Carcinogenesis, Carcinoma of lung	Altered Intercellular Communication	Despite growing recognition of an etiologic role for inflammation in lung carcinogenesis, few prospective epidemiologic studies have comprehensively investigated the association of circulating inflammation markers with lung cancer.	24249745
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Some circulating inflammation marker levels are associated with prospective lung cancer risk.	24249745
Inappropriate ADH Syndrome	Altered Intercellular Communication	Syndrome of inappropriate antidiuretic hormone associated with aripiprazole.	24249761
Inflammation, Choroidal Effusions	Altered Intercellular Communication	Examination revealed bilateral hypotony, right anterior chamber inflammation, and right choroidal effusion.	24251433
allergic inflammation	Altered Intercellular Communication	Further studies are needed to determine whether allergic inflammation contributes toward epileptogenesis.	24251558
Intracerebroventricular route	Altered Intercellular Communication	Treatment of congenital neurotransmitter deficiencies by intracerebral ventricular injection of an adeno-associated virus serotype 9 vector.	24251946
Orbital Pseudotumor	Altered Intercellular Communication	Immunohistochemical staining is used to diagnose IgG4-RD in patients with orbital inflammation.	24252013
Dacryoadenitis	Altered Intercellular Communication	Among the nine patients, eight had dacryoadenitis, one had infraorbital nerve swelling, and another one had IgG4-related orbital inflammation.	24252013
Stomatitis, Nasopharyngitis, Reduced	Altered Intercellular Communication	Frequent adverse events for 52 weeks in the iguratimod + MTX group were nasopharyngitis, upper respiratory tract inflammation, stomatitis, lymphocyte decrease, AST increase, ALT increase and blood iron decrease.	24252050
Senile Plaques, Inflammation, Cerebral Ischemia	Altered Intercellular Communication	Our results suggest that the reduction in ferroportin levels are likely associated with cerebral ischaemia, inflammation, the loss of neurons due to the well-characterised protein misfolding, senile plaque formation and possibly the ageing process itself.	24252754
Granulomatous inflammation	Altered Intercellular Communication	Histological examination revealed a necrotising granulomatous inflammation, culture showed a Mycobacterium avium complex (MAC).	24252838
Refractory anemias, Inflammation	Altered Intercellular Communication	Addition of pioglitazone to RA standard of care significantly improves aortic elasticity and decreases inflammation and disease activity with minimal safety issues.	24252844
Inflammation, Myopathy	Altered Intercellular Communication	Muscle biopsy showed a necrotizing myopathy with no inflammation or autoimmune changes.	24252882
Inflammation, Colorectal Carcinoma, Neoplasms	Altered Intercellular Communication	Progression of colorectal cancer (CRC) is strongly associated with inflammation and other desmoplastic reactions in the tumor cell-surrounding tissue.	24253852
Inflammation, Stomach Carcinoma, Neoplasms	Altered Intercellular Communication	Postoperative complications that can cause prolonged inflammation have an obvious impact not only on the OS but also on the DSM of patients with gastric cancer even if the tumor is resected curatively.	24254205
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Although nonalcoholic fatty liver disease (NAFLD) is conventionally assessed histologically for lobular features of inflammation, development of portal fibrosis appears to be associated with disease progression.	24254368
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, GDC Disease Response Terminology	Altered Intercellular Communication	The presence of portal inflammation in NAFLD was strongly correlated with disease severity (fibrosis stage) and the DR.	24254368
Inflammation, Non-alcoholic Fatty Liver Disease, Histopathologic Grade differentiation	Altered Intercellular Communication	Knowledge of the complex cellular composition of the portal inflammatory infiltrate and HPC/DR niche in NAFLD will shape future functional studies to elucidate the contribution of portal inflammation to HPC differentiation and NAFLD pathogenesis.	24254368
Dermatitis	Altered Intercellular Communication	Among them 20 cases went to see a doctor for painless mass, and two cases shown as skin inflammation.	24257306
Inflammation, Cardiovascular Diseases, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Altered microRNA expression has been reported in processes related to cardiovascular disease and PM exposure, such as systemic inflammation, endothelial dysfunction, and atherosclerosis.	24257509
Inflammation, Hyperplasia, Neoplasms	Altered Intercellular Communication	Stromal inflammation and increased microvessel density was evident in EAF2-deficient mice on a pure C57BL/6J background at an early age and preceded the development of the histologic epithelial hyperplasia and neoplasia found in the prostates of older EAF2(-/-) animals.	24260246
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Periostin links mechanical strain to inflammation in abdominal aortic aneurysm.	24260297
Inflammation, Glucocorticoid deficiency with achalasia, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Abdominal aortic aneurysms (AAAs) are characterized by chronic inflammation, which contributes to the pathological remodeling of the extracellular matrix.	24260297
APP gene, Inflammation	Altered Intercellular Communication	Although mechanical stress has been suggested to promote inflammation in AAA, the molecular mechanism remains uncertain.	24260297
Inflammation	Altered Intercellular Communication	Our findings indicated that periostin plays an important role in mechanotransduction that maintains inflammation via FAK activation in AAA.	24260297
Inflammation, diabetic	Altered Intercellular Communication	Diabetic patients could do as well as non-diabetic patients without inflammation on peritoneal dialysis.	24260402
palladium, Inflammation, diabetic	Altered Intercellular Communication	Diabetic patients on peritoneal dialysis (PD) have lower survival and are more likely complicated with inflammation than their non-diabetic counterparts.	24260402
palladium, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Here, we explored the interaction effects between diabetes and inflammation on the survival of PD patients.	24260402
palladium, Inflammation	Altered Intercellular Communication	Diabetics on PD were more likely to have inflammation than non-diabetics on PD, and they presented with elevated hsCRP (52.7% vs. 47.3%, P = 0.03) or decreased SA (77.9% vs. 62.7%, P < 0.001) levels.	24260402
Inflammation, diabetic	Altered Intercellular Communication	Diabetic patients could do as well as non-diabetic patients without inflammation on peritoneal dialysis.	24260402
palladium, Inflammation, diabetic	Altered Intercellular Communication	Active strategies should be implemented to improve inflammation status in diabetic patients on PD.	24260402
Diabetes Mellitus, Cardiovascular system	Altered Intercellular Communication	Then, several multivariable adjusted stratified Cox regression models were constructed for these groups to explore the predicted role of diabetes on all-cause or cardiovascular death under inflammatory or non-inflammatory conditions.	24260402
Inflammation	Altered Intercellular Communication	The role of inflammasomes in chronic inflammation has been the subject of intense research in recent years.	24260763
Inflammation, Acid reflux	Altered Intercellular Communication	Catheter substitution was necessary in three patients during the first year, because of stoma inflammation due to enteric reflux between the stoma and the catheter.	24261024
Inflammation	Altered Intercellular Communication	Inflammation may be important in contributing to EHG and warrants further investigation.	24262327
Inflammation	Altered Intercellular Communication	Patients with HFpEF often show signs of chronic systemic inflammation, and experimental studies have shown that interleukin-1 (IL-1), a key proinflammatory cytokine, impairs myocardial relaxation.	24262762
Granulomatosis, Systemic Vasculitis, Acute sinusitis	Altered Intercellular Communication	Although granulomatosis with polyangiitis (GPA) can affect a large number of organ systems and produce a broad spectrum of clinical symptoms, skeletal involvement is very rare, with the exception of facial bone involvement associated with destructive nasal and sinus inflammation.	24263148
Necrotizing granulomatous inflammation, Fibrinoid necrosis	Altered Intercellular Communication	A histopathologic analysis of the lung mass revealed chronic granulomatous inflammation with fibrinoid necrosis, and he was diagnosed with GPA.	24263148
Inflammation, Respiratory Hypersensitivity, Inflammatory disorder	Altered Intercellular Communication	Asthma is a chronic inflammatory disorder of the airways that is characterized by episodic and reversible airflow obstruction, airway hyper-responsiveness, and underlying inflammation.	24264497
Inflammation, Periodontitis, Infection, Pneumonia	Altered Intercellular Communication	The chronic infections associated with periodontitis can increase the risk for aspiration pneumonia in older adults and has been implicated in the pathogenesis of chronic inflammation that impairs general health.	24264502
Gingivitis, Attachment (action), Periodontal Diseases	Altered Intercellular Communication	The severity of periodontal disease can be categorized as mild, moderate, or severe on the basis of multiple measurements of periodontal pocket depth, attachment loss, and gingival inflammation around teeth.	24264502
Granulomatous inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Nasal biopsy revealed granulomatous inflammation and vasculitis involving small vessels.	24265538
Schistosomiasis mansoni, Nephritis	Altered Intercellular Communication	Monocyte chemotactic protein-1 (MCP-1) in patients with chronic schistosomiasis mansoni: evidences of subclinical renal inflammation.	24265821
Inflammation, Traumatic injury	Altered Intercellular Communication	This protein has a role in the recruitment of monocytes to injury and inflammation sites .	24265821
Nephritis	Altered Intercellular Communication	The increase of MCP-1 in the urine evidences that there is silent renal inflammation in these patients and the inflammatory status is not interrupted by specific treatment of the offending agent.	24265821
Necrotizing granulomatous inflammation, Glomerulonephritis, Vasculitis, CTCAE	Altered Intercellular Communication	It is manifested as granulomatous necrotizing inflammation of the upper and lower parts of the respiratory tract, glomerulonephritis and systemic vasculitis involving most frequently the skin and oral mucous membrane.	24266321
Inflammation, Diverticular Diseases	Altered Intercellular Communication	Since diverticular disease appeared slight and no inflammation signs were evident, colon resection was not performed.	24267118
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Inflammatory factors and low HDL-C relate to CHD risk, but whether inflammation attenuates any protective association of high HDL-C is unknown.	24267235
Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Compared to high HDL-C/low-inflammation categories (referent), adjusted HRs for incident CHD were increased for those with high HDL-C and high CRP (HR = 1.50, p < 0.01) or highest IL-6 tertile (HR = 1.40, p < 0.05), but not with highest Lp-PLA2 tertile.	24267235
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	The protective relation of high HDL-C for incident CHD appears to be attenuated by greater inflammation.	24267235
Inflammation, Heparin-induced thrombocytopenia, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Our data demonstrate that heparin-induced mobilization of vessel-bound MPO is closely linked to coronary plaque burden and thus further corroborate the evidence for the intimate involvement of this enzyme in vascular pathophysiology, as well as the importance of inflammation in atherosclerosis.	24267251
Hypertension, CTCAE, Dermatitis	Altered Intercellular Communication	Chronic skin inflammation may plays a role in the aetiology of hypertension in both disorders.	24267636
Primary malignant neoplasm, Colitis	Altered Intercellular Communication	In animal models, excess luminal iron exacerbates colonic inflammation and cancer development.	24267915
Inflammation	Altered Intercellular Communication	Inflammation is likely to play a role because steroids often improve these phenomena.	24267950
Idiopathic aortitis	Altered Intercellular Communication	Idiopathic aortitis (IA) is characterized by giant cell or lymphoplasmacytic inflammation of aorta without a secondary cause.	24268116
Inflammation, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Resistin is a peptide hormone that is secreted from lipid cells and is linked to type-2 diabetes, obesity, and inflammation.	24268420
Inflammation, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Resistin is a peptide hormone that is secreted from lipid cells and is linked to type-2 diabetes, obesity, and inflammation.	24268420
Arterial Stiffness, Mucopolysaccharidosis I	Altered Intercellular Communication	Although yet to be confirmed, increased cIMT and arterial stiffness in MPS I and II patients may be a consequence of inflammatory signaling pathways triggered by heparan or dermatan sulfate-derived oligosaccharides.	24268528
Osteomyelitis, Discitis	Altered Intercellular Communication	Gallium inflammation scan and magnetic resonance image of the spine disclosed osteomyelitis and discitis at the level of L4-5.	24269007
Inflammation, SDSL gene	Altered Intercellular Communication	Aberrant angiogenesis and localized inflammation contribute to the formation of CSDH.	24269089
Inflammation	Altered Intercellular Communication	Mesenchymal cells (fibroblasts) of the airway wall respond to cholinergic stimulation by releasing pro-inflammatory and chemotactic cytokines and may thus contribute to chronic inflammation of the lung.	24269928
Pulmonary arterial hypertension, Inflammation, Polycyclic Hydrocarbons, Aromatic	Altered Intercellular Communication	Pulmonary arterial hypertension (PAH) is associated with sustained inflammation known to promote DNA damage.	24270264
Tumor necrosis, Inflammation	Altered Intercellular Communication	Healthy PASMCs treated with a clinically relevant dose of tumor necrosis factor-a harbored a similar phenotype, suggesting that inflammation induces DNA damage and PARP-1 activation in PAH.	24270264
Arterial Stiffness, Inflammation, Dyslipidemias, Obesity	Altered Intercellular Communication	These findings suggest that EPA improves the arterial stiffness in association with an increase in the EPA/AA ratio and a decrease in inflammation in obese patients with dyslipidemia.	24270918
Inflammation	Altered Intercellular Communication	The transcription factor PPAR-g plays various roles in lipid metabolism, inflammation, cellular differentiation, and apoptosis.	24272485
Inflammation	Altered Intercellular Communication	Contrast medium suppresses FMD, probably through an increased production of oxygen-derived free radicals and inflammation although adequate hydration was given in type 2 diabetes.	24272602
N-formyl-13-dihydrocarminomycin, Inflammation, Presenile dementia	Altered Intercellular Communication	These findings demonstrate that microglial activation does not initiate or exacerbate NFD, and we conclude that CNS inflammation is unlikely to be causally involved in the development of NFD characteristic of AD dementia.	24272705
Infarction, Inflammation, Ischemic	Altered Intercellular Communication	Inflammation may not only be the consequence of brain infarction but it may also contribute to ischemic damage.	24273300
Inflammation, Dermatologic disorders, Toxic Epidermal Necrolysis, Necrosis	Altered Intercellular Communication	Toxic epidermal necrolysis (TEN) is an idiosyncratic, potentially life-threatening skin disease characterized by widespread inflammation and necrosis of the epidermis and mucous membranes.	24273804
Inflammation, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	The aim of the present study was to test the hypothesis whether serum resistin is associated with markers of malnutrition and inflammation in elderly non-diabetic adults in different stages of CKD including hemodialysis.	24273936
Chronic Kidney Diseases	Altered Intercellular Communication	These results indicate that resistin increases as GFR declines and may be involved in the malnutrition-inflammation state and the reverse epidemiology phenomenon present in elderly, non-diabetic patients with CKD.	24273936
Inflammation, Chronic sinusitis	Altered Intercellular Communication	Does eosinophilic inflammation affect the outcome of endoscopic sinus surgery in chronic rhinosinusitis in Koreans?	24274208
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	The implication of eosinophilic inflammation in chronic rhinosinusitis (CRS) has not been sufficiently studied in Asians.	24274208
Inflammation, Craniosynostosis	Altered Intercellular Communication	The results suggest that eosinophilic inflammation in CRS may not be related to the surgical outcome in Koreans.	24274208
Arthralgia, Inflammation, Knee pain	Altered Intercellular Communication	Patterns of change in SF-36, systemic inflammation biomarkers, and the 6-minute walk test did not differ significantly between groups during the 8-week study Results from this randomized, double blind, placebo-controlled community trial support the use of the Instaflex(tm) dietary supplement in alleviating joint pain severity in middle-aged and older adults, with mitigation of difficulty performing daily activities most apparent in subjects with knee pain.	24274358
Inflammation, Toxic effect	Altered Intercellular Communication	Concurrent chemoradiotherapy (CCRT) induces toxicities from inflammation and immunological suppression.	24274379
Inflammation, Squamous cell carcinoma of esophagus	Altered Intercellular Communication	The question is whether immunonutrition (IN) during CCRT reduces inflammation and improves the immune function in patients with esophageal squamous cell carcinoma (ESCC).	24274379
Crohn Disease, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Dysbiosis of gut fungal microbiota is associated with mucosal inflammation in Crohn's disease.	24275714
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Shifts of gut fungal microbiota composition may be associated with mucosal inflammation and disease activity of CD.	24275714
Toxic effect, Diarrhea, Leukopenia, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The toxicity profile was similar across age groups, with the exception of diarrhea, mucosal inflammation, and grade 3-4 neutropenia and leukopenia, which were slightly more common in elderly patients in both treatment arms.	24277116
Inflammation, Impaired, Uveitis	Altered Intercellular Communication	In Cohort 1, only one patient was symptomatic for ocular impairment, and uveitis without inflammation was the most common presentation.	24277596
Malnutrition, Pneumonitis, Osteopenia	Altered Intercellular Communication	The mechanism for early bone loss in CF patients are multifactorial: chronic pulmonary inflammation, malnutrition, reduced physical activity, delayed pubertal maturation.	24277958
Visual Impairment, Vasculitis, CTCAE, Vitreous inflammatory cells	Altered Intercellular Communication	Significant differences were found for size of active lesions, unilateral macular involvement, unilateral visual impairment, vitreous inflammation, synechiae, and vasculitis, with higher values observed throughout for Colombian patients.	24278490
Inflammation, Carcinogenesis	Altered Intercellular Communication	Other protein modifications related to carcinogenesis and inflammation and the various factors that may play a role in orchestrating complex interactions which influence tissue integrity following irradiation were investigated.	24279338
Inflammation, Obesity, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Chronic inflammation and risk factors, such as obesity, smoking, and high cholesterol, are well-established risk factors for CHD.	24279678
ARCN1 gene, Inflammation	Altered Intercellular Communication	COPD is characterized by chronic inflammation in the pulmonary compartment and in the systemic circulation.	24281671
Inflammation, Dental Plaque, Rupture	Altered Intercellular Communication	Biomarkers of endothelial inflammation (hsCRP), plaque destabilization, and rupture (sVCAM, MMP-9, PAPP-A, ADMA) were quantified.	24281903
Inflammation, thromboembolic, atherosclerotic, Atherosclerotic lesion	Altered Intercellular Communication	Identification of inflamed atherosclerotic lesions in vivo using PET-CT. Inflammation plays a major pathogenetic role in the development of atherosclerotic plaques and related thromboembolic events.	24282108
Inflammation	Altered Intercellular Communication	Fluorodeoxyglucose positron emission tomography (FDG-PET) has been shown to be useful for tracing inflammation within plaques.	24282108
Obstructive Ureterocele	Altered Intercellular Communication	This finding suggests that FDG uptake reflects the severity of atherosclerotic vessel wall inflammation, and in stenotic lesions, it could be an indicator of their vulnerability.	24282108
Dry Eye Syndromes, Diabetes Mellitus	Altered Intercellular Communication	Analysis of spectral counts of tear proteins showed that, compared to healthy controls, patients with diabetes and dry eye syndrome had increased expression of apoptosis-related proteins, like annexin A1, and immunity- and inflammation-related proteins, including neutrophil elastase 2 and clusterin, and glycometabolism-related proteins, like apolipoprotein A-II.	24282230
Gingivitis, Impaired cognition, Disease	Altered Intercellular Communication	The association of lower cognitive scores with edentulism suggests that past oral diseases may be a risk indicator for cognitive decline, whereas the association with gingival inflammation indicates a possible effect of cognitive decline on oral health.	24282266
Inflammation, Fibrosis Assessment, Atrophic	Altered Intercellular Communication	Tissue KIM-1 expression was determined immunohistochemically and KIM-1 staining was scored semiquantitatively, as well as tubulointerstitialis (TIN), inflammation, atrophy, and fibrosis.	24282337
Allergic asthma, physiopathological, Airway structure	Altered Intercellular Communication	Allergic asthma is characterized by airway inflammation in response to antigen exposure, leading to airway remodeling and lung dysfunction.	24283210
Inflammation, Vascular System Injuries	Altered Intercellular Communication	Deletion of thioredoxin-interacting protein preserves retinal neuronal function by preventing inflammation and vascular injury.	24283717
Retinal Ganglion Cells, Retinitis	Altered Intercellular Communication	Targeting TXNIP expression prevented early retinal ganglion cell death, glial activation, retinal inflammation and secondary neuro/microvascular degeneration and preserved retinal function.	24283717
Inflammation	Altered Intercellular Communication	Interleukin-1 plays a key role in inflammation and keratinocyte activation.	24283773
Inflammation, Fibrosis Assessment, Colonic Diverticulitis, Crohn Disease	Altered Intercellular Communication	Inflammation and fibrosis are present in both colonic diverticulitis and Crohn's disease (CD).	24283919
Inflammation	Altered Intercellular Communication	Lymphocytic and neutrophil inflammation scores were similar in both groups (P = 0.771 and P = 0.562).	24283919
Inflammation	Altered Intercellular Communication	The findings confirm that inflammation and its association with altered molecular patterns of mucosal healing may play an important role in the phenotype of the diseases.	24283919
Inflammation	Altered Intercellular Communication	eGFR level in CAD patients with normal serum creatinine is associated with coronary artery severity, inflammation level and serves as an independent predictor for MACCE in this patient cohort.	24284182
Refractory anemias, Inflammation, Rheumatoid Arthritis, Anemia	Altered Intercellular Communication	Anemia of inflammation (AI) is a common complication of rheumatoid arthritis (RA) and has a negative impact on RA symptoms and quality of life.	24286116
Inflammation, hafnium, Depression, CTCAE	Altered Intercellular Communication	Hence, the goal is to examine the relative importance of inflammation, disease severity and personality as predictors of depression in HF patients.	24286171
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Inflammation, brain natriuretic peptide and left ventricular ejection fraction were not related to depression over time.	24286171
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Personality factors, but not inflammation, were independent concomitants of depressive symptoms in patients with HF.	24286171
Refractory anemias, Rheumatoid Arthritis, Chronic inflammation, Atherosclerosis	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a complex polygenic disease associated with chronic inflammation, accelerated atherosclerosis and increased cardiovascular (CV) mortality.	24286297
methyldopa, Inflammation	Altered Intercellular Communication	Evidence indicates that the suppression of the ubiquitin-proteasome system (UPS) contributes to the accumulation of toxic proteins and inflammation in retinal pigment epithelium (RPE), the functional abnormalities and/or the degeneration of which are believed to be the initiators and major pathologies of AMD.	24286321
Refractory anemias, Rheumatoid Arthritis, Damage, Inflammation	Altered Intercellular Communication	Oncostatin M (OSM) has been implicated in the pathophysiology of rheumatoid arthritis (RA) through its effect on inflammation and joint damage.	24286335
Inflammation, Nephritis	Altered Intercellular Communication	These data suggest that serum levels of LL37 and IFN-a may reflect both local renal inflammation and systemic inflammation.	24286516
Inflammation, Immune dysregulation, Arthritis	Altered Intercellular Communication	However, some patients have persistent arthritis after spirochetal killing, which may result from excessive inflammation, immune dysregulation and infection-induced autoimmunity.	24286535
Inflammation, Arthritis	Altered Intercellular Communication	In patients with antibiotic-refractory arthritis, the frequencies of IFN-g-producing CD56bright and CD56dim NK cells remained high in SF, even after spirochetal killing, suggesting that these cells contribute to excessive inflammation and immune dysregulation in joints, and iNKT cells, which may have immunomodulatory effects, were often absent.	24286535
Chronic infectious disease, Inflammation, Traumatic injury, Neoplasms	Altered Intercellular Communication	Commonly mucoceles form secondary to obstruction of a sinus outflow tract or from mucosal gland entrapment from chronic infection, inflammation, iatrogenic trauma, external trauma, or neoplasm.	24286944
Inflammation, muscle mass	Altered Intercellular Communication	These findings in a limited group of individuals suggest that regular physical endurance activity may play a role in reducing some markers of systemic inflammation, even within the normal range, and in maintaining muscle mass with aging.	24287006
Inflammation, Ischemic stroke	Altered Intercellular Communication	Clinical and experimental data have demonstrated that inflammation plays fundamental roles in the pathogenesis of ischemic stroke.	24288444
Refractory anemias, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Classical CVD risk factors and inflammation are both implicated in causing endothelial dysfunction in RA.	24289091
Refractory anemias, Inflammation, Atherosclerosis	Altered Intercellular Communication	Classical CVD risk factors, but not RA disease-related inflammation, predicted microvascular endothelium-dependent and endothelium-independent function, macrovascular endothelium-independent function and carotid atherosclerosis.	24289091
Inflammation, Atherosclerosis	Altered Intercellular Communication	Cumulative inflammation was not associated with microvascular and macrovascular endothelial function, but a weak association was apparent between area under the curve for CRP and carotid atherosclerosis.	24289091
Refractory anemias, Inflammation	Altered Intercellular Communication	Classical CVD risk factors may be better long-term predictors of vascular function and morphology than systemic disease-related inflammation in patients with RA.	24289091
Inflammation, Global systolic dysfunction	Altered Intercellular Communication	Our study is the first to demonstrate an association between serum CA 125 levels and LV systolic dysfunction via inflammation in patients on maintenance HD.	24289262
Inflammation, Damage, Obesity, Abdominal, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Abdominal obesity and low-grade systemic inflammation as markers of subclinical organ damage in type 2 diabetes.	24290615
Sandawe language, Inflammation, Atherosclerosis, Obesity, Arterial Stiffness, Damage, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Both SAD and WC are feasible measures of obesity, and both provide information on inflammation, atherosclerosis and arterial stiffness in type 2 diabetes, while SAD appears to be slightly more robustly associated with subclinical organ damage than WC.	24290615
Inflammation, Periprosthetic Fractures, Osteolysis	Altered Intercellular Communication	Patient radiographs were scored for osteolysis and periprosthetic tissues were immunostained and imaged to quantify polyethylene wear, inflammation, and five osteoinflammatory and oxidative stress-responsive factors.	24290740
Inflammation, Osteolysis	Altered Intercellular Communication	Similar to wear debris and inflammation, osteolysis correlated with HMGB1.	24290740
Inflammation, Typhoid Fever	Altered Intercellular Communication	Further, the increase in albumin and haptoglobin in chronic typhoid carriers shows their role in free radical generation, inflammation, and monocyte cell signaling.	24291468
Inflammation, Pancreatitis, Necrosis	Altered Intercellular Communication	The infiltration of surrounding tissue and nearby organs by inflammation and fat necrosis in necrotizing pancreatitis has not been reported previously in a pediatric patient.	24292046
Inflammation	Altered Intercellular Communication	Inflammation has previously been shown to increase levels of extracellular b-nicotinamide adenine dinucleotide (NAD(+)).	24292505
Inflammation, Endothelial dysfunction, ETV3 wt Allele, Cardiovascular Diseases	Altered Intercellular Communication	Furthermore, we show that the presence of the MetS is characterized by endothelial dysfunction, as suggested by lower fRHI, as well as by endothelial inflammation, which likely contributes to the increased cardiovascular disease risk associated with the MetS.	24292639
Inflammation, Lymphoma, Leukemia, T-Cell	Altered Intercellular Communication	HTLV-I bZIP factor (HBZ), which is expressed in all adult T-cell leukemia cells, plays a critical role in the development of lymphoma and systemic inflammation.	24292748
Pneumonitis	Altered Intercellular Communication	HBZ and Foxp3 likely have a role in the development of lung inflammation.	24292748
Inflammation, Brain Injuries	Altered Intercellular Communication	It may contribute to chronic inflammation and tissues injury.	24292797
Inflammation, Osteoarthritis, Knee	Altered Intercellular Communication	Effect of low-dose oral prednisolone on symptoms and systemic inflammation in older adults with moderate to severe knee osteoarthritis: a randomized placebo-controlled trial.	24293578
Pain Distress Question, Inflammation	Altered Intercellular Communication	Outcome measures included pain reduction and improvement in function scores and systemic inflammation markers.	24293578
ARCN1 gene, Inflammation	Altered Intercellular Communication	Effect of high-dose N-acetylcysteine on airway geometry, inflammation, and oxidative stress in COPD patients.	24293993
Inflammation, Diverticulum, Diverticulosis	Altered Intercellular Communication	On the basis of morphological and immunological study of biopsies of the colon in patients with diverticulosis was revealed that microscopic inflammation of the mouth of the diverticulum is characterized by several features that include excessive proliferation of the epithelium, the predominance of macrophage reaction in the development of the immune response, increased cell adhesion and unusual ratio between the expression of cytokines and other regulatory molecules.	24294770
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Serum TNF-alpha and IL-6 have predictive value for development of inflammation and fibrosis in patients with AH and can be used as non-invasive markers of fibrosis.	24294778
Inflammation, hepcidin	Altered Intercellular Communication	This improvement correlates with the degree of suppression of systemic inflammation, reduction in hepcidin and haptoglobin and increase in iron-binding capacity.	24295403
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	Study of TLR4 and IL-8 gene polymorphisms in H.pylori-induced inflammation in gastric cancer in an ethnic Kashmiri population.	24295404
Inflammatory abnormality of the eye, Infection by human herpesvirus 6	Altered Intercellular Communication	Recurrent ocular surface inflammation associated with human herpesvirus 6 infection.	24296955
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Recent evidence suggests that angiogenesis and inflammation contribute to the development and progression of osteoarthritis (OA).	24297611
Inflammation, Non-Small Cell Lung Carcinoma, Neoplasms	Altered Intercellular Communication	Low-serum sodium concentration, which was associated with tumor status and inflammation, had negative prognostic influence in completely resected NSCLC.	24297635
Cerebral Vasospasm	Altered Intercellular Communication	Therefore, further research should focus on anti-inflammation as a therapeutic target against cerebral vasospasm and on the CSF as the optimum place where such inflammatory action practically brought about.	24297765
Autoimmune Diseases, Myasthenia Gravis	Altered Intercellular Communication	Myasthenia gravis (MG) is a severely debilitating autoimmune disease that is due to a decrease in the efficiency of synaptic transmission at neuromuscular synapses.	24297891
Communicable Diseases, Inflammation	Altered Intercellular Communication	The exposed tube was closed successfully without recurrence, graft thinning, or graft-related infection or inflammation over a 20-month follow-up period.	24299729
Inflammation	Altered Intercellular Communication	Acute inflammation was histologically proven in 18/18 specimens (100%) and additional chronic inflammation in 12/18 (66.7%).	24300350
Inflammation	Altered Intercellular Communication	Group One patients were found to have a significantly higher level of the marker of chronic inflammation IgG and IL-8, amounting respectively to 22.43+-0.75 mg/ml and to 6.34+-1.008 pg/ml and 16.35+-0.84 mg/ml (p=0.01) and 3.96+-0.399 pg/ml (p=0.01) in Group Two patients.	24300501
Communicable Diseases, Observation Method - Coagulation, Inflammation, HIV-1 Infection Pathway	Altered Intercellular Communication	Inflammation and coagulation biomarkers interleukin (IL)-6 and D-dimer are predictive of all-cause mortality in chronic HIV-1 infection; however, their predictive value in individuals with recent infection has not been described.	24300544
Acute inflammation, Chronic Acalculous Cholecystitis	Altered Intercellular Communication	Good results were obtained in 93% of patients with chronic calculous cholecystitis, as well as acute inflammation.	24300608
Schizophrenia, Chronic disease, Unipolar Depression	Altered Intercellular Communication	In chronic diseases such as schizophrenia and major depression, decrease in astroglial numbers and functional capabilities are, arguably, fundamental for pathological developments being responsible for neurotransmitter disbalance and failures in connectivity within neural networks.	24301046
Inflammation, SERPINB3 wt Allele	Altered Intercellular Communication	In conclusion, these results suggested that the G allele of the CCR5 59029 polymorphism might be a risk factor due to the loss of receptor function that might cause increased inflammation leading to the development of OSCC.	24301940
Inflammation, Phenylketonurias	Altered Intercellular Communication	Phenylketonuria is not a risk factor for gut mucosa inflammation: a preliminary observation.	24302186
Inflammation	Altered Intercellular Communication	In PKU high oxidative stress and inefficiency of free radical scavenging may lead to systemic chronic inflammation.	24302186
Inflammation, Obesity	Altered Intercellular Communication	Obesity is associated with insulin resistance and chronic low-grade inflammation.	24302564
Inflammation, Fibrosis Assessment, Fatty degeneration, FAM126A gene	Altered Intercellular Communication	A biopsy confirmed the suspected diagnosis of HCC; interestingly, the non-neoplastic liver was surrounded and characterized by the presence of steatosis and ballooning, and being absent of lobular inflammation and fibrosis.	24302697
Non-alcoholic Fatty Liver Disease, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Low serum sex hormone-binding globulin is associated with nonalcoholic fatty liver disease in type 2 diabetic patients.	24303796
Inflammation, Peyronie Disease	Altered Intercellular Communication	Long-term multimodal therapy (verapamil associated with propolis, blueberry, vitamin E and local diclofenac) on patients with Peyronie's disease (chronic inflammation of the tunica albuginea).	24304332
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Systemic inflammation has been implicated in cancer development and progression.	24306668
Inflammation, Carcinogenesis, Squamous cell carcinoma of esophagus	Altered Intercellular Communication	These results suggest, for the first time, that upregulation of PLCE1 is correlated with increased expression of NF-kB-related proteins in Kazakh patients with ESCC, suggesting that interaction between PLCE1 with the NF-kB signal pathway may be responsible for the carcinogenesis of ESCC, such as ESCC-related inflammation.	24307345
Acute myocardial infarction, Inflammation, Dental Plaque	Altered Intercellular Communication	The presence of CX3CR1 polymorphisms could influence the incidence and the outcome of acute myocardial infarction, altering the inflammation of the whole coronary tree by the impaired recruitment of Th1 polarized subpopulation in the coronary plaque.	24307998
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Recent studies suggest that chronic inflammation is crucial in the development and progression of prostate cancer (CaP).	24308236
Inflammation, Carcinogenesis	Altered Intercellular Communication	Interleukin-6 (IL-6) is a proinflammatory cytokine that plays an important role in intraprostatic inflammation and thus carcinogenesis.	24308236
Gingivitis	Altered Intercellular Communication	COPB subjects had significantly worse periodontal conditions than controls (p < 0.05) with regard to each parameter of periodontal condition, except for gingival inflammation.	24308240
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	An index of daily step count and systemic inflammation predicts clinical outcomes in chronic obstructive pulmonary disease.	24308588
Arterial Stiffness, ARCN1 gene, Inflammation	Altered Intercellular Communication	Arterial stiffness in patients with COPD: the role of systemic inflammation and the effects of pulmonary rehabilitation.	24311762
Arterial Stiffness, Inflammation, Chronic Obstructive Airway Disease, ARCN1 gene	Altered Intercellular Communication	Clear evidence for an association between systemic inflammation and increased arterial stiffness in patients with chronic obstructive pulmonary disease (COPD) is lacking.	24311762
Arterial Stiffness, ARCN1 gene, Inflammation	Altered Intercellular Communication	Arterial stiffness in COPD is not related to systemic inflammation and does not respond to state-of-the-art pulmonary rehabilitation.	24311762
Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease with unknown aetiology that causes the immune system to attack the joints (synoviums), leading to chronic inflammation.	24311851
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Liver inflammation and fibrosis, viral load and genotype did not correlate with BMD measurements.	24312334
Gastritis, Gastritis, Atrophic	Altered Intercellular Communication	These findings demonstrate that cholesteryl a-glucosides play critical roles in H. pylori-mediated gastric inflammation and precancerous atrophic gastritis.	24312443
Renal Insufficiency, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	In conclusion, in elderly men, GDF-15 improves prognostication of both cardiovascular, cancer mortality and morbidity beyond established risk factors and biomarkers of cardiac, renal dysfunction and inflammation.	24312445
Shock, Inflammation, Hypoxia	Altered Intercellular Communication	Trauma/hemorrhagic shock (T/HS) results in hepatic hypoxia that drives inflammation.	24312451
Inflammation, Idiopathic pulmonary hypertension	Altered Intercellular Communication	Markers of thrombogenesis and fibrinolysis and their relation to inflammation and endothelial activation in patients with idiopathic pulmonary arterial hypertension.	24312667
Inflammation, Idiopathic pulmonary hypertension	Altered Intercellular Communication	Fibrinolysis, inflammation, and endothelial activation were closely interrelated in IPAH.	24312667
Streptococcal Infections, Have Autoimmune or Inflammatory Condition, Encephalomyelitis, Acute Disseminated	Altered Intercellular Communication	We suggest that the pathophysiological mechanism in the present case was not necrotic/cytotoxic but autoimmune inflammation, which is compatible with acute disseminated encephalomyelitis associated with streptococcal infection.	24313006
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Strong evidence suggests that systemic inflammation and central adiposity contribute to and perpetuate metabolic syndrome.	24313349
Inflammation	Altered Intercellular Communication	Macroscopic evaluation of the joints during arthroscopy revealed a significant decrease of local inflammation mainly in good ACR50 responders.	24313444
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Circulating progenitor cells in rheumatoid arthritis: association with inflammation and oxidative stress.	24313545
Inflammation, Atherosclerosis, Refractory anemias, Vascular lesions, Rheumatoid Arthritis	Altered Intercellular Communication	To evaluate the association between inflammation, oxidative stress, and circulating progenitor cell (CPC) number and redox equilibrium, vascular lesions and accelerated atherosclerosis in rheumatoid arthritis (RA).	24313545
Arterial Stiffness, Inflammation, Refractory anemias	Altered Intercellular Communication	Our data show a link between inflammation, oxidative stress, and the impairment of the antioxidant system of CPCs and their number, and with arterial stiffness in RA subjects.	24313545
Inflammation, Malnutrition, Traumatic injury	Altered Intercellular Communication	Trauma patients with DWH frequently suffer from protein malnutrition and reduced plasma concentrations of several micronutrients probably due to inflammation, increased requirement, and oxidative burden.	24314073
prostatitis	Altered Intercellular Communication	Relationship of chronic histologic prostatic inflammation in biopsy specimens with serum isoform [-2]proPSA (p2PSA), %p2PSA, and prostate health index in men with a total prostate-specific antigen of 4-10 ng/ml and normal digital rectal examination.	24315305
Prostate carcinoma, Structure of posterior cerebral artery	Altered Intercellular Communication	To investigate the relationship between serum [-2]proPSA (p2PSA) and derivatives with chronic histologic prostatic inflammation (CHPI) in men undergoing prostate biopsy for suspected prostate cancer (PCa).	24315305
goal oriented behavior, Toxoplasmosis	Altered Intercellular Communication	Latent T. gondii infection may be of relevance to goal-directed behavior as it alters dopaminergic neural transmission.	24315729
Inflammatory Bowel Diseases	Altered Intercellular Communication	Inflammatory bowel disease (IBD) is a systemic inflammatory condition that affects the entire organism, not only the bowel.	24315776
Inflammation	Altered Intercellular Communication	Increasing evidence suggests that systemic inflammation is associated with many pathophysiological processes including frailty in older adults.	24316038
Inflammation, Diverticular Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation associated with diverticular disease could predispose to cardiovascular disease.	24316104
Proteinuria, Nephritis, Kidney Diseases	Altered Intercellular Communication	Urinary cytokines after HCT: evidence for renal inflammation in the pathogenesis of proteinuria and kidney disease.	24317123
Proteinuria, Inflammation, Albuminuria	Altered Intercellular Communication	After HCT, elevated urinary levels of pro-inflammatory cytokines are associated with development of albuminuria and proteinuria, suggesting early intra-renal inflammation as an important pathogenetic mechanism.	24317123
Inflammation	Altered Intercellular Communication	Eight patients showed inflammatory extension beyond the lacrimal gland, such as thickened rectus muscle (n = 6), inflammation of the optic nerve (n = 2), and retrobulbar inflammation (n = 3).	24318531
Inflammation, IgG4-Related Sclerosing Disease, Dacryoadenitis, Allergic	Altered Intercellular Communication	IgG4-related dacryoadenitis showed various ophthalmologic symptoms due to extensive inflammation beyond the lacrimal gland, frequent association with other IgG4-related disease or allergic phenomena, and steroid responsiveness.	24318531
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Polyneuropathy, Ulcer	Altered Intercellular Communication	Prospective studies should establish whether the pronounced reduction of cutaneous LCs detected in recently diagnosed type 2 diabetes could promote a cutaneous immunogenic imbalance toward inflammation predisposing to polyneuropathy and foot ulcers.	24319115
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD) is associated with inflammation.	24321183
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	CKD patients with inflammation treated with atorvastatin had significantly less eGFR decline.	24321183
Inflammation, SERPINB3 wt Allele	Altered Intercellular Communication	CPA is a common disease and the monitoring as well as the treatment of such a chronic oral inflammation may be beneficial in reducing one potential cause of OSCC.	24321243
Inflammation, Traumatic injury, Intraosseous Route of Drug Administration	Altered Intercellular Communication	The origin of this lesion is uncertain; however, factors such as local trauma, inflammation, intraosseous hemorrhage, and genetic abnormalities have been identified as possible causes.	24321310
Inflammation, Granuloma	Altered Intercellular Communication	The cavity wall showed chronic inflammation and occasional giant cells but no granulomas and no microorganisms.	24321524
Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Balloon Dilatation	Altered Intercellular Communication	Although there were no differences between groups in the histological severity of steatosis, inflammation, ballooning degeneration, NAFLD activity score, or histological grade, subjects with OSA/hypoxemia had significantly more severe hepatic fibrosis.	24321532
Steatohepatitis, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Increasing percentage of time with oxygen saturation <=90% was related to NAFLD inflammation grade (r = 0.44; P = .03), degree of hepatic steatosis (r = -0.50; P = .01), NAFLD activity score (r = 0.42; P = .04), aspartate aminotransferase level (r = 0.56; P = .004), and alanine aminotransferase level (r = 0.44; P = .03).	24321532
Familial spinal arachnoiditis, Inflammation	Altered Intercellular Communication	Spinal arachnoiditis is a disease characterized by inflammation and scarring of the arachnoid membrane of the spinal cord.	24321827
Inflammation, Hyperplasia	Altered Intercellular Communication	All along the treatment and after it, the hyperplasia and the gingival inflammation not only maintained but they even got worse.	24322040
Sarcoidosis, Inflammatory abnormality of the eye	Altered Intercellular Communication	Therefore, sarcoidosis should be kept in mind when evaluating a patient with ocular inflammation.	24322273
Fibrous, Inflammation	Altered Intercellular Communication	Pathological examination of thoracoscopic biopsy specimen showed fibrous tissue with mild inflammation and no malignant feature.	24322358
Inflammation	Altered Intercellular Communication	Based on our findings, we postulate that age-associated biochemical changes may accentuate the inflammation associated with OAB.	24323058
Prostate carcinoma, prostatitis	Altered Intercellular Communication	Baseline prostate inflammation is associated with a reduced risk of prostate cancer in men undergoing repeat prostate biopsy: results from the REDUCE study.	24323568
Prostate carcinoma, prostatitis, Structure of posterior cerebral artery	Altered Intercellular Communication	The current study was performed to evaluate whether baseline acute and chronic prostate inflammation among men with an initial negative biopsy for prostate cancer (PCa) increased the risk of subsequent PCa detection in a clinical trial with systematic biopsies.	24323568
Structure of posterior cerebral artery, prostatitis	Altered Intercellular Communication	PCa, acute prostate inflammation, and chronic prostate inflammation were assessed by central review.	24323568
Inflammation	Altered Intercellular Communication	Acute and chronic inflammation and both were detected in 46 baseline biopsies (1%), 3931 baseline biopsies (63%), and 892 baseline biopsies (14%), respectively.	24323568
Inflammation	Altered Intercellular Communication	Acute and chronic inflammation were found to be significantly associated with each other (P<.001).	24323568
Inflammation	Altered Intercellular Communication	Baseline acute and chronic inflammation were both found to be independently associated with a lower PCa risk.	24323568
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	From a clinical standpoint, inflammation in negative biopsies for PCa may lower the risk of subsequent PCa detection.	24323568
Degenerative polyarthritis, Inflammation, Obesity	Altered Intercellular Communication	The decrease in CRP levels in patients with SAP, combined with OA and obesity with concomitant therapy by the proposed method, indicates a decrease in systemic inflammation.	24323963
ARCN1 gene, Inflammation, Cardiovascular Diseases, Chronic Obstructive Airway Disease, physiopathological	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by low pulmonary function, inflammation, free radical production, vascular dysfunction, and subsequently a greater incidence of cardiovascular disease.	24324045
Colorectal Carcinoma, Primary Neoplasm	Altered Intercellular Communication	Prognostic value of preoperative inflammation-based prognostic scores in patients with stage IV colorectal cancer who undergo palliative resection of asymptomatic primary tumors.	24324099
Autoimmune Diseases, Chronic lymphocytic inflammation	Altered Intercellular Communication	Primary SS is an autoimmune disease characterized by chronic lymphocytic inflammation and ectopic germinal centre (GC) formation within salivary glands.	24324211
Tissue damage, Inflammation, Endothelial dysfunction, Carotid Atherosclerosis	Altered Intercellular Communication	The preferential proinflammatory Th1 activation suggests that actin could contribute to endothelial dysfunction, tissue damage, and systemic inflammation in carotid atherosclerosis.	24324294
Inflammation, Prostate carcinoma, Benign prostatic hypertrophy	Altered Intercellular Communication	[Differences in pathological features of histological inflammation between benign prostatic hyperplasia and prostate cancer].	24325107
Inflammation, Prostate carcinoma, Benign prostatic hypertrophy, Structure of posterior cerebral artery	Altered Intercellular Communication	To study the pathologic features and differences of tissue inflammation in benign prostatic hyperplasia (BPH) and prostate cancer (PCa).	24325107
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	The HE stained slice obtained by prostate biopsy from 143 BPH and 106 PCa were reviewed to determine whether the tissue inflammation existed.	24325107
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	There were 142 cases found tissue inflammation in 143 BPH patients and 104 cases in 106 PCa patients, so the incidences of tissue inflammation in BPH and PCa were 99.	24325107
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	The anatomical location of inflammation was significant difference between BPH and PCa group (P<0.	24325107
Interstitial inflammation	Altered Intercellular Communication	3%) was primary in BPH, and interstitial inflammation (56.7%) was the main pattern in PCa.	24325107
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	The incidences of tissue inflammation were high in both BPH and PCa, but the pathological features of tissue inflammation were different between BPH and PCa.	24325107
Inflammation, Thrombosis, Systemic Inflammatory Response Syndrome, Leukocytosis	Altered Intercellular Communication	Although inflammation is considered a risk factor for deep vein thrombosis, the prognostic significance of both systemic inflammatory response syndrome (SIRS) and leukocytosis has not been elucidated.	24325351
Inflammation, Edema, Ischemia	Altered Intercellular Communication	Inflammation and/or ischemia may increase vascular permeability and disrupt the blood-aqueous barrier by increasing levels of inflammatory factors in patients with CRVO and macular edema.	24325604
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The human gut microbiota and microbial influences on lipid and glucose metabolism, satiety, and chronic low-grade inflammation are known to be involved in metabolic syndrome.	24325907
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Several studies show that high serum C-reactive protein (CRP) levels are associated with an increased risk of diabetes, data that strongly supports a possible role for inflammation in diabetogenesis.	24326321
Inflammation, Carcinogenesis, Pancreatic carcinoma	Altered Intercellular Communication	Inflammation has been implicated in carcinogenesis and progression of pancreatic cancer.	24326841
Inflammation, Dental Plaque	Altered Intercellular Communication	The plaque composition, cellularity, severity of inflammation, and atheroma-associated macrophages and foam cells were compared with virtual histology.	24326894
Inflammation, Critical Illness	Altered Intercellular Communication	We investigated whether C-reactive protein (CRP) as indicator of acute inflammation is associated with maximal isometric handgrip strength in non-critically ill patients.	24327120
Inflammation, Granuloma, Retinal Detachment, Parasitic cyst, Retinal fibrosis	Altered Intercellular Communication	The eye examination in the hospital showed damage of the left eye, red eye, retinal fibrosis, retinal detachment, inflammation of the eye tissues, retinal granulomas, and a parasitic cyst inside.	24327783
Necrotizing granulomatous inflammation, Coagulative necrosis, Fibrous	Altered Intercellular Communication	Pathologically, chronic granulomatous inflammation composed of coagulation necrosis with rim of fibrous tissues and granulations was seen.	24327784
Inflammation	Altered Intercellular Communication	The profiles of mesenteric and pancreatic lymph nodes differ and often change reciprocally due to directed migration of T cells towards the site of inflammation.	24328490
Inflammation, Insulitis, Infiltration	Altered Intercellular Communication	CD25(-)FoxP3(+) Treg are markedly increased in the pancreatic infiltrates in late stages of inflammation, possibly an effort to counteract destructive insulitis.	24328490
Inflammation, Liver damage, Fatty degeneration	Altered Intercellular Communication	Mice were sacrificed after 3 weeks, and steatosis, inflammation, apoptosis, and liver damage were assessed.	24329600
Inflammation, Fatty degeneration	Altered Intercellular Communication	CHOP deficiency did not affect steatosis but significantly reduced apoptotic cells, inflammation scores, and serum liver enzymes.	24329600
Inflammation, Injury of liver, Steatohepatitis, Fibrosis Assessment, Carcinogenesis	Altered Intercellular Communication	CHOP deficiency attenuated apoptosis, inflammation, fibrosis, and tumorigenesis under fat-loading conditions, indicating that a therapeutic strategy targeting CHOP might be effective for fat-induced liver injury and protecting against promotion of carcinogenesis in patients with liver steatosis.	24329600
Inflammation, Hypertensive (finding), Albuminuria	Altered Intercellular Communication	sRAGE may play a role in the pathogenic processes that link albuminuria, chronic inflammation and oxidative stress in hypertensive patients.	24329736
Inflammation, Paresis, Myelitis, Transverse, Bladder Sphincter Dysfunction	Altered Intercellular Communication	Transverse myelitis (TM) is the inflammation of the spinal cord characterized by rapidly evolving muscle weakness in the lower extremities, defects in sensory level and sphincter dysfunction.	24330286
Inflammation	Altered Intercellular Communication	Altered expression profiling in SpA and AS samples demonstrates that disease pathogenesis is associated with both systemic inflammation as well as local tissue alterations that may underlie tissue damaging modelling and remodelling outcomes.	24330574
Inflammation, Spondylarthropathies	Altered Intercellular Communication	This supports the hypothesis that initial systemic inflammation in spondyloarthropathies transfers to and persists in the local joint environment, and might subsequently mediate changes in genes directly involved in the destructive tissue remodelling.	24330574
Communicable Diseases, Inflammation, Comorbidity	Altered Intercellular Communication	A prospective study: inflammation, infection and comorbidity in patients on long-term dialysis.	24330609
HD Term Type, Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Age, CVD and CVA are predictors for mortality in patients on HD patients, but the presence of C. pneumoniae IgG and inflammation are not.	24330609
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The NF-kB family of transcription factors is up-regulated in inflammation and different cancers.	24330732
Inflammation, Gangrene, Perforation (observation), Hernia	Altered Intercellular Communication	The diagnosis is always mistaken for the one of incarcerated or strangled hernia, the correct diagnosis being established intraoperatively, occasion which exposes the cecal appendix by opening the herniary bag, found in different morphological stages of inflammation that can go as far as gangrene or even perforation.	24331333
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Inflammation plays a key role in the development of benign prostatic hyperplasia.	24331343
Inflammation, Inflammatory pain	Altered Intercellular Communication	Prostaglandin E2 (PGE2) is an important inflammation factor found in enlarged prostatic tissue that can be the main cause of inflammatory pain.	24331343
Airway structure, Asthma	Altered Intercellular Communication	The process of airway inflammation in the lungs of nonsmokers who die of asthma (fatal asthma) has not been reported in detail.	24331389
Inflammation, Periodontitis, diabetic	Altered Intercellular Communication	Chronic inflammation of periodontitis aggravates glycemic control in type 2 diabetic patients through aggravation of insulin resistance.	24331774
Inflammation, Radicular Cyst	Altered Intercellular Communication	Several cytokines participate in the mechanisms of inflammation, tissue repair, and bone resorption associated with periapical cysts.	24331993
Inflammation	Altered Intercellular Communication	Mean number of mast cells on the superficial region of the fibrous capsule was higher in cysts showing intense superficial inflammation and exocytosis.	24331993
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	Eyes with uveitis, seen at 5 academic ocular inflammation centers in the United States, for which ME was documented to be currently present and the principal cause of reduced visual acuity (<20/40).	24332536
Inflammation, Damage	Altered Intercellular Communication	Evidence of significant ocular damage from inflammation (posterior synechiae and hypotony) portends a lower incidence of visual recovery.	24332536
Inflammation	Altered Intercellular Communication	Cancer-associated inflammation is increasingly recognised to be an important determinant of oncological outcome.	24332571
Cataract, Inflammation	Altered Intercellular Communication	To analyze the cause of fibrinous inflammation in eyes with capsular tension rings (CTRs) after cataract surgery.	24333013
Airway structure, Asthma	Altered Intercellular Communication	Patients with refractory asthma frequently have neutrophilic airway inflammation and respond poorly to inhaled corticosteroids.	24333186
Inflammation, Fibrosis Assessment, Nephrolithiasis	Altered Intercellular Communication	S100A8 and fibronectin, representatives of inflammation and fibrosis, respectively, were up-regulated in nephrolithiasis renal tissues.	24333391
Inflammation, Fibrosis Assessment, Kidney Calculi	Altered Intercellular Communication	Therefore, inflammation and fibrosis are suggested to be involved in the formation of kidney calculi.	24333391
Angina, Unstable, Arteritis	Altered Intercellular Communication	Plasma pentraxin 3 (PTX3) levels are increased in patients with arterial inflammation and especially unstable angina pectoris (UAP).	24333560
Inflammation	Altered Intercellular Communication	Four of them showed acute inflammation in the gallbladder while pathological signs of chronic inflammation in the gallbladder wall were detected in eight cases.	24333981
Inflammation	Altered Intercellular Communication	Fcg receptor upregulation is associated with immune complex inflammation in the mouse retina and early age-related macular degeneration.	24334446
methyldopa, Inflammation	Altered Intercellular Communication	Several lines of evidence suggest the involvement of antibodies and immune complex inflammation in AMD, a blinding disease with a strong inflammatory component.	24334446
methyldopa, Inflammation, Retinitis	Altered Intercellular Communication	To examine this further, we developed a novel experimental mouse model of retinal inflammation and evaluated whether inflammation associated with immune complex formation was present in eyes of AMD donors.	24334446
Inflammation	Altered Intercellular Communication	Colonoscopy showed inflammation of the descending colon and histopathology revealed patchy increase in intraepithelial lymphocytes.	24334470
Refractory anemias, Inflammation, Rheumatoid Arthritis, Disease	Altered Intercellular Communication	To assess the predictive value of magnetic resonance imaging (MRI)-detected subclinical inflammation for subsequent radiographic progression in a longitudinal study of patients with rheumatoid arthritis (RA) in clinical remission or low disease activity (LDA), and to determine cutoffs for an MRI inflammatory activity acceptable state in RA in which radiographic progression rarely occurs.	24334647
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Inflammation and disease activity are associated with high circulating cardiac markers in rheumatoid arthritis independently of traditional cardiovascular risk factors.	24334650
Inflammation	Altered Intercellular Communication	The association between HS-cTnT, NT-proBNP, and CRP, together with the correlation between HS-cTnT and disease activity, support the link between myocardial injury/dysfunction and inflammation.	24334650
Inflammatory abnormality of the eye	Altered Intercellular Communication	The patients with VKH disease were treated with high-dose systemic corticosteroids, which were tapered off gradually over a period of 6 months or more by the treating ophthalmologists according to the severity of the ocular inflammation.	24335059
Inflammation	Altered Intercellular Communication	In conclusion, as an inexpensive, simple, and accessible marker of inflammation, the NLR may be useful in predicting the presence and severity of MS in patients with RMVD.	24335245
Inflammation, Arthritis	Altered Intercellular Communication	Concordance between inflammation at physical examination and on MRI in patients with early arthritis.	24336009
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	MRI is increasingly used to measure inflammation in rheumatoid arthritis (RA) research, but the correlation to clinical assessment is unexplored.	24336009
Inflammation, Joints	Altered Intercellular Communication	This study determined the association and concordance between inflammation of small joints measured with MRI and physical examination.	24336009
Inflammation	Altered Intercellular Communication	The MRI data were first analysed continuously and then dichotomised to analyse the concordance with inflammation at joint examination.	24336009
Inflammation, Wrist joint	Altered Intercellular Communication	In 86% of the swollen MCP joints and in 92% of the swollen wrist joints any inflammation on MRI was present.	24336009
Inflammation	Altered Intercellular Communication	In 27% of the non-swollen MCP joints and in 66% of the non-swollen wrist joints any MRI inflammation was present.	24336009
Inflammation, MTTP wt Allele	Altered Intercellular Communication	Vice versa, of all MCP, wrist and MTP joints with inflammation on MRI 64%, 61% and 77%, respectively, were not swollen.	24336009
Inflammation	Altered Intercellular Communication	Inflammation on MRI is not only present in clinically swollen but also in non-swollen joints.	24336009
Inflammation	Altered Intercellular Communication	Chronic inflammation is frequently associated with tumorigenesis in elderly people.	24336323
Inflammation, Neoplasms	Altered Intercellular Communication	By contrast, young people without chronic inflammation often develop tumors considered independent of chronic inflammation but driven instead by mutations.	24336323
Inflammation, Neoplasms	Altered Intercellular Communication	Thus, whether inflammation has a significant role in tumor progression in tumors driven by mutations remains largely unknown.	24336323
Acute Coronary Syndrome, Inflammation, Platelet aggregation test result	Altered Intercellular Communication	MKC improved the prognosis of patients with acute coronary syndrome, possibly through inhibiting the platelet aggregation, fighting against inflammation, and protecting the vascular endothelial function.	24338186
Inflammation, Tuberculosis, Necrosis, Necrotizing granulomatous inflammation, Tuberculosis, Laryngeal, Caseous necrosis	Altered Intercellular Communication	We studied 19 cases of laryngeal tuberculosis with typical histopathology (chronic granulomatous inflammation with caseous necrosis and langhans-type giant cells) and 6 cases of laryngeal tuberculosis with atypical histopathology (chronic granulomatous inflammation or chronic inflammation without necrosis).	24338196
Inflammation, Malignant Neoplasms, Tuberculosis	Altered Intercellular Communication	The primary clinical diagnosis was malignancy in 17 cases, tuberculosis in 5 cases, and nonspecific inflammation in 3 cases.	24338196
Inflammation, Fibrosis Assessment, Heart failure	Altered Intercellular Communication	Galectin-3, a biomarker associated with fibrosis and inflammation, has been implicated in development and progression of heart failure (HF) and predicts increased mortality and morbidity in this condition.	24338533
Inflammation, Fibrosis Assessment, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	We studied the involvement of IL-13 in inflammation and fibrosis in UC and Crohn's disease (CD).	24338958
Inflammation	Altered Intercellular Communication	Hispanics had significantly lower SES, greater inflammation, as well as higher tender and swollen joint counts.	24339449
methyldopa, Inflammation	Altered Intercellular Communication	The present research supports the role of oxidative stress and inflammation in AMD and highlights the role of therapy directed against these risk factors.	24340512
Inflammation	Altered Intercellular Communication	The patient with p22 defect was diagnosed at two months of age; and gastric wall granuloma, inflammation in proximal femur was detected.	24341149
Inflammation, "Alzheimers Disease", Impaired cognition	Altered Intercellular Communication	Inflammation plays a crucial role in the pathophysiology of Alzheimer's disease and cognitive impairment.	24342014
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Obesity is frequently associated with low-grade inflammation of adipose tissue (AT), and the increase in adipose tissue macrophages (ATMs) is linked to an increased risk of type 2 diabetes.	24343232
Inflammation, Malaria, Intradermal Route of Drug Administration	Altered Intercellular Communication	Hemoglobin, iron deficiency (ID), vitamin A deficiency (VAD), inflammation, malaria, anthropometry, and STH ova were measured.	24343884
Perifolliculitis	Altered Intercellular Communication	The prevalence of trachomatous inflammation-follicular in children aged 1-9 years ranged from 0.3% in Sokoto South to 15.6% in Kalgo LGA.	24344228
Inflammation, Hemorrhage	Altered Intercellular Communication	These presentations result either from peritoneal inflammation and subsequent peritoneal bleeding or retroperitoneal cavity pathology rupturing into the peritoneal cavity.	24344496
Inflammation	Altered Intercellular Communication	On microscopy he had multiple foci of acute and chronic inflammation.	24344506
Orthodontic, Gingivitis, Dental Plaque	Altered Intercellular Communication	Orthodontic appliances can promote accumulation of dental plaque, with associated enamel decalcification or gingival inflammation.	24345204
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Compared with HC, the mucin chemotype in UC was less sulphated and inversely correlated with the degree of mucosal inflammation.	24345279
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Mucin composition strongly correlates with the degree of mucosal inflammation, and to a lesser extent with DSV burden.	24345279
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Decreased sulphation of mucins has been associated with inflammation in ulcerative colitis.	24345279
Moorens ulcer", Ulcerative inflammation	Altered Intercellular Communication	Mooren's ulcer is a severe ulcerative inflammation of the cornea.	24345289
Gastrointestinal inflammation	Altered Intercellular Communication	The involvement of NOPs in the pathophysiology of GI inflammation has been suggested, but due to the lack of selective NOP agonists, it never fully elucidated.	24345466
Cataract, Pain Distress Question, Inflammatory abnormality of the eye	Altered Intercellular Communication	Once-daily nepafenac ophthalmic suspension 0.3% to prevent and treat ocular inflammation and pain after cataract surgery: phase 3 study.	24345529
Cataract, Eye pain, Inflammation	Altered Intercellular Communication	To evaluate once-daily nepafenac 0.3% to prevent and treat ocular pain and inflammation after cataract surgery.	24345529
Inflammation	Altered Intercellular Communication	The primary endpoint was the percentage of patients with a cure for inflammation (score of 0 for both aqueous cells and flare) at day 14.	24345529
Inflammation, Pain Distress Question	Altered Intercellular Communication	Significantly more nepafenac 0.3% patients had no inflammation (68.4% versus 34.0%) and were pain free (91.0% versus 49.7%) at day 14 than vehicle patients (both P<.0001).	24345529
Cataract, Pain Distress Question, Inflammatory abnormality of the eye	Altered Intercellular Communication	Once-daily nepafenac 0.3% was noninferior to nepafenac 0.1% 3 times daily for prevention and treatment of ocular inflammation and pain following cataract surgery.	24345529
Inflammation, Appendicitis, CTCAE, Perforation (observation), Necrosis	Altered Intercellular Communication	Emergency surgery is performed on patients with appendicitis in the belief that inflammation of the appendix may progress to necrosis and perforation.	24345979
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Many cases of appendicitis, however, resolve with conservative treatment, and necrotic appendicitis may represent a different disease rather than the end result of inflammation of the appendix.	24345979
Inflammation, Necrosis	Altered Intercellular Communication	In addition, our findings add weight to the increasing volume of data showing that necrosis of the appendix is a disease different from simple inflammation.	24345979
Inflammation, Acne Vulgaris, Acne fulminans	Altered Intercellular Communication	We present the case of a 18-year-old male patient in whom acne fulminans evolved from acne vulgaris grade IV and after inflammation resolution started treatment with oral isotretinoin.	24346917
Inflammation, Observation Method - Coagulation, Primary malignant neoplasm	Altered Intercellular Communication	Increasing evidence indicates the involvement of inflammation and coagulation in cancer progression and metastases.	24347236
Inflammation	Altered Intercellular Communication	Children who are burned >40% total body surface area lose significant quantities of both bone and muscle mass because of acute bone resorption, inflammation, and endogenous glucocorticoid production, which result in negative nitrogen balance.	24347438
Inflammation, Dyslipidemias, Atherosclerosis	Altered Intercellular Communication	Chronic hemodialysis patients experience accelerated atherosclerosis contributed to by dyslipidemia, inflammation, and an impaired antioxidant system.	24348043
Inflammation, Gland, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Chronic inflammation, neutrophil activity and glandular atrophy showed statistically significant association with H. pylori infection.	24349327
Inflammation, Metabolic acidosis	Altered Intercellular Communication	This relationship between low bicarbonate levels and adverse outcome could be related to enhanced inflammation and a more rapid loss of RRF associated with metabolic acidosis.	24349396
Communicable Diseases, Additional, Inflammation	Altered Intercellular Communication	Additional sepsis biomarkers do not aid in discriminating inflammation from infection.	24349403
Inflammation, Protein-Energy Malnutrition	Altered Intercellular Communication	Inflammation but not dietary macronutrients insufficiency associated with the malnutrition-inflammation score in hemodialysis population.	24349471
Inflammation, Malnutrition, Protein-Energy Malnutrition	Altered Intercellular Communication	In conclusion, malnutrition is very common in South China hemodialysis population and these data indicated that inflammation but not dietary macronutrients insufficiency might be the candidate cause for malnutrition in hemodialysis population.	24349471
Inflammation, Cerebral Small Vessel Diseases	Altered Intercellular Communication	This study was designed to explore the relationship between low-grade inflammation and renal microangiopathy in T2DM.	24350298
Inflammation, Edema	Altered Intercellular Communication	It has been hypothesized that inflammation and edema in the surgery site has a major role in voice change after thyroidectomy.	24351352
Inflammation, Cardiac Death, Atherosclerosis	Altered Intercellular Communication	All of these foods and nutrients may affect cholesterol, inflammation, the development of atherosclerosis, and, therefore, risk of cardiac death.	24351877
Carcinogenesis, Acute and chronic inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Recently, it was reported that gene editing enzyme, activation-induced cytidine deaminase (AID), is expressed in precursor and cancer epithelial cells during carcinogenesis associated with chronic inflammation/infection and that this enzyme induces mutation of tumor-suppressor genes.	24351917
Inflammation	Altered Intercellular Communication	The leukocyte architecture observed in normal skin was distorted in inflammation and disease.	24352044
Inflammation	Altered Intercellular Communication	Advantages deriving from early control of joint inflammation may explain the maintenance of results at follow-up.	24352823
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Lymphatic dysregulation leads to inflammation, scarring, and fibrosis, but inadvertent injection of these vessels can be avoided with anatomical knowledge.	24353247
ARTERIAL TORTUOSITY SYNDROME, Inflammation, Hemorrhage, Atherosclerosis, Dental Plaque	Altered Intercellular Communication	Plaque hemorrhage, inflammation and microvessel density are key determinants of plaque vulnerability in native coronary atherosclerosis (ATS).	24354875
Inflammation, CAV1 gene	Altered Intercellular Communication	This study investigates the role of intraplaque hemorrhage (IPH) and its relation with inflammation and microvessels in cardiac allograft vasculopathy (CAV) in posttransplanted patients.	24354875
Inflammation	Altered Intercellular Communication	Intralesion inflammation, microvessels and IPH were assessed semi-quantitatively.	24354875
Inflammation, CAV1 gene	Altered Intercellular Communication	Inflammation was present in 31/35 (88.6%) of CAV lesions.	24354875
Inflammation, CAV1 gene, Microvessels	Altered Intercellular Communication	IPH, associated with microvessel damage and inflammation, is an important feature of CAV.	24354875
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Relationship between inflammation and infliximab pharmacokinetics in rheumatoid arthritis.	24354889
Refractory anemias, Inflammation	Altered Intercellular Communication	The influence of methotrexate and inflammation on infliximab clearance suggests that individual adjustment of infliximab doses according to disease activity may be useful in RA.	24354889
Inflammation	Altered Intercellular Communication	The clinical and histopathological findings of our reported case lend support to the possible role of inflammation in the pathogenesis of HH/HHE syndrome.	24355077
Inflammation, Obesity	Altered Intercellular Communication	Benefit of physical fitness against inflammation in obesity: role of beta adrenergic receptors.	24355098
Inflammation, Inflammatory disorder, Obesity	Altered Intercellular Communication	Evidence shows that both poor physical fitness and obesity are linked to low-grade inflammation and inflammatory diseases.	24355098
Inflammation	Altered Intercellular Communication	However, their relative roles on inflammation and underlying mechanisms remain unclear.	24355098
Inflammation, Overweight, Obesity	Altered Intercellular Communication	We examined circulating levels of inflammatory cytokines TNF, IL-1b, IL-6 and b-AR sensitivity of, 70 overweight or obese compared to 26 normal-weight, otherwise healthy individuals in order to investigate the associations among obesity, physical fitness, and low-grade inflammation and to examine the role of b-ARs in these relationships.	24355098
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Age, diabetes, and inflammation together explained the inverse association between HRV and PWV.	24356038
Inflammation	Altered Intercellular Communication	Inflammation may play a role in the pathogenesis of both low HRV and high PWV.	24356038
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Inflammation plays a crucial role in the pathogenesis and prognosis of stroke.	24356104
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Our data support the view that there is increased inflammation in CKD and DN.	24356550
Inflammation, hepcidin	Altered Intercellular Communication	Further studies should examine whether increased weight contributes towards hepcidin elevation in predialysis individuals, in whom there is a lesser burden of systemic inflammation.	24356769
Hernia of abdominal cavity, Inflammation	Altered Intercellular Communication	Prevalence of systemic inflammation and micronutrient imbalance in patients with complex abdominal hernias.	24356980
Hernia of abdominal cavity, Inflammation	Altered Intercellular Communication	To determine the prevalence of low-grade inflammation, micronutrient imbalances and associated clinical profiles in patients being evaluated for complex abdominal hernia repair.	24356980
Inflammation, Protein-Energy Malnutrition	Altered Intercellular Communication	In this comorbidity-rich population with known variability in surgical outcomes, the prevalence of chronic inflammation and micronutrient deficiency are high enough to warrant systemic preoperative evaluation given their possible effect on wound healing and convalescence.	24356980
Inflammatory, Inflammation	Altered Intercellular Communication	The correlation between the presence of leukocytes in the CSF of patients suffering from MS and the number of inflammatory lesions as detected by magnetic resonance imaging suggests that inflammation at the choroid plexus contributes to the disease, although in a yet unknown fashion.	24356983
Barrett Esophagus, Inflammation	Altered Intercellular Communication	Cyclooxygenase-2 and inflammation mediators have a crucial role in reflux-related esophageal histological changes and Barrett's esophagus.	24357184
Inflammation, Anemia, hepcidin	Altered Intercellular Communication	A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin.	24357728
Inflammatory, Inflammation, Anemia, hepcidin	Altered Intercellular Communication	Similarly to severe human anemia of inflammation, the B abortus model shows multifactorial pathogenesis of inflammatory anemia including iron restriction from increased hepcidin, transient suppression of erythropoiesis, and shortened erythrocyte lifespan.	24357728
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	With growing evidence on the role of inflammation in cancer biology, the systemic inflammatory response has been postulated as having prognostic significance in a wide range of different cancer types.	24357794
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation has a critical role in the pathogenesis and progression of cancer.	24357796
Airway structure	Altered Intercellular Communication	Pro-resolution mediator lipoxin A4 and its receptor in upper airway inflammation.	24358628
Inflammation	Altered Intercellular Communication	The resolution of inflammation is an active process controlled by several anti-inflammatory and pro-resolution mediators.	24358628
Inflammation	Altered Intercellular Communication	Lipoxin A4, an endogenous lipid mediator, is a potential pro-resolution mediator that could attenuate inflammation.	24358628
Airway structure	Altered Intercellular Communication	This study was conducted to elucidate the role of lipoxin A4 in upper airway inflammation.	24358628
Airway structure	Altered Intercellular Communication	These results indicate that lipoxin A4 may play a role in the resolution of upper airway inflammation.	24358628
palladium, Inflammation	Altered Intercellular Communication	In addition, sites with inflammation and PD >=5 mm had significantly greater odds of exhibiting Fas, sFasL, and caspase-3 expression compared with sites without inflammation and PD <5 mm (P <0.05).	24359166
Inflammation	Altered Intercellular Communication	The inter-relation between Ab, inflammation and cholinergic signaling is complex, with each feeding back onto the others to drive disease progression.	24359497
Conjunctivitis	Altered Intercellular Communication	We consider such treatment a very effective initial immunosuppressive alternative in patients with moderate conjunctival inflammation and in cases of rapid progression.	24359845
Nonalcoholic Steatohepatitis, Inflammation, Steatohepatitis, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Overall, 45% of the biopsy specimens analyzed had steatosis >=33%, 22% had grade >=2 lobular inflammation, 81% had portal inflammation, 29% had ballooned hepatocytes, 35% had "suspicious/borderline" steatohepatitis, 8% had definite nonalcoholic steatohepatitis, 34% had an NAFLD activity score >=4, and 46% had fibrosis (38% mild/moderate and 8% bridging/cirrhosis).	24360992
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Fatty degeneration	Altered Intercellular Communication	Marked steatosis (50% vs 24%) and fibrosis (54% vs 12%) were significantly more common in the patients with mildly elevated ALT compared with those with normal ALT, with no difference in ballooning, inflammation, or NAFLD activity score >=4 between the 2 groups.	24360992
Inflammation, Dyslipidemias, Abdominal aortic calcification	Altered Intercellular Communication	Osteoprotegerin, inflammation and dyslipidemia are associated with abdominal aortic calcification in non-diabetic patients on peritoneal dialysis.	24361071
Inflammation, Injury of pancreas	Altered Intercellular Communication	After pancreatic injury or inflammation, proteases such as trypsin activate the complement system and can potentially cause coagulation and leukoembolization of retinal precapillary arterioles.	24362324
Inflammation	Altered Intercellular Communication	Ineffectual antibody production with misdirected cytokine responses and excess inflammation in the airways are common to both groups.	24362692
Inflammation, Diabetic Retinopathy, Obesity, Disturbance, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation, haemostatic disturbance, and obesity: possible link to pathogenesis of diabetic retinopathy in type 2 diabetes.	24363502
Diabetic Retinopathy, Inflammation, GDC Disease Response Terminology	Altered Intercellular Communication	The pathogenesis of diabetic retinopathy (DR) is insufficiently understood but may possibly involve chronic, low-grade inflammation.	24363502
Inflammation, Diabetic Retinopathy, Endothelial dysfunction, Obesity, Disturbance	Altered Intercellular Communication	Interrelations between obesity, inflammation, haemostatic disturbance, and other risk factors may possibly play an important additional role in endothelial dysfunction involved in the pathogenesis of diabetic retinopathy.	24363502
Crohn Disease	Altered Intercellular Communication	Role of the advanced glycation end products receptor in Crohn's disease inflammation.	24363518
Inflammation	Altered Intercellular Communication	RAGE is up-regulated in CD, especially in inflamed areas, and it appears to play a role in the mechanisms involved in chronic inflammation.	24363518
Inflammation, Liver cyst, Hemangioma, Infiltration	Altered Intercellular Communication	The remaining 46 nodules were benign (28 were of hepatocyte origin, nine were hepatic cysts, seven were hemangiomas, one was chronic inflammation, and one was focal fat infiltration).	24363528
Inflammation, Abdominal Abscess	Altered Intercellular Communication	She developed an intra-abdominal abscess around the remnant pancreas head 31 d after the surgery, and computed tomography (CT) showed an occluded portal vein due to the spreading inflammation around the abscess.	24363537
Inflammation, Left ventricular systolic dysfunction	Altered Intercellular Communication	Hemodialysis-induced regional left ventricular systolic dysfunction and inflammation: a cross-sectional study.	24364893
Inflammation, Endothelium, Global systolic dysfunction	Altered Intercellular Communication	We tested the hypothesis that hemodialysis-induced regional LV systolic dysfunction is associated with inflammation and endothelial injury.	24364893
Inflammation, Global systolic dysfunction	Altered Intercellular Communication	Intradialysis courses of markers of inflammation, bioincompatibility, and endothelial function did not differ in patients with versus without hemodialysis-induced regional LV systolic dysfunction.	24364893
Inflammation, Calcification of coronary artery, Atherosclerosis	Altered Intercellular Communication	Coronary angiography or computed tomography for quantification of coronary calcifications in our patients was not performed; therefore, we could not relate markers of inflammation to the extent of atherosclerosis.	24364893
Synovitis, Inflammation, Osteoarthritis, Knee	Altered Intercellular Communication	Degree of synovitis on MRI by comprehensive whole knee semi-quantitative scoring method correlates with histologic and macroscopic features of synovial tissue inflammation in knee osteoarthritis.	24365722
Inflammation, Synovitis	Altered Intercellular Communication	To evaluate the association between synovitis on contrast enhanced (CE) MRI with microscopic and macroscopic features of synovial tissue inflammation.	24365722
Inflammation, Anal Fistula	Altered Intercellular Communication	The patient had received operations for anal fistula and inflammation three times.	24365737
Inflammation	Altered Intercellular Communication	CRSwNP is characterized by significant elevations in circulating moDCs, which is associated with systemic Th2-biased inflammation.	24367054
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Circulating moDCs are associated with mucosal inflammation on CT imaging in CRSsNP.	24367054
skin impairment, Inflammation, Diabetes Mellitus, Cardiovascular Diseases	Altered Intercellular Communication	We previously observed an association between these mutations and type 2 diabetes and hypothesized that an inherited impairment of skin barrier functions could facilitate low-grade inflammation and hence increase the risk of diabetes and cardiovascular disease.	24367652
Weight decreased, Inflammatory abnormality of the eye	Altered Intercellular Communication	While dynasore did not reduce ocular inflammation, it did provide significant protection against weight loss.	24367704
Multiple polyps, Inflammation, Ulcerative Colitis, Entrapment of Device, Stasis	Altered Intercellular Communication	Significantly, 7 of 10 cases with postoperative diagnoses of UC (70%) had Crohn's-like transmural inflammation exclusively within the polyposis segments attributed to fecal entrapment and stasis and accounting for the Crohn's-like clinical complications in these cases.	24368253
Inflammation, Fuchs Endothelial Dystrophy	Altered Intercellular Communication	Inflammation can be an etiologic factor of Fuchs' dystrophy according to previous studies.	24368317
Inflammation, Traumatic injury	Altered Intercellular Communication	Persistent inflammation, immunosuppression, and catabolism syndrome after severe blunt trauma.	24368353
Multiple Organ Failure, Inflammation	Altered Intercellular Communication	We recently proffered that a new syndrome persistent inflammation, immunosuppression, and catabolism syndrome (PICS) has replaced late multiple-organ failure as a predominant phenotype of chronic critical illness.	24368353
Inflammation, Traumatic injury	Altered Intercellular Communication	We performed a secondary analysis of the Inflammation and Host Response to Injury database of adults with severe blunt trauma.	24368353
Inflammation, Lung diseases	Altered Intercellular Communication	Bio-active trace metals have been identified in respiratory tract secretions of subjects with lung disease and may potentially influence bacterial virulence, inflammation and disease severity.	24369896
Inflammation, Necrosis	Altered Intercellular Communication	Elevated concentrations of sputum metal ions appear to be associated with cell/tissue necrosis and inflammation in subjects with CF and NCFB.	24369896
Communicable Diseases, Allergy - Charge Type Reason, Inflammation, Respiration Disorders	Altered Intercellular Communication	Non-invasive sampling of airway epithelial-lining-fluid by nasal lavage (NL) is an emerging method to monitor allergy, infection and inflammation in patients with respiratory diseases.	24370751
Chronic infectious disease, Inflammation	Altered Intercellular Communication	Influences of repeated NL, centrifugation setups, repeated freezing and thawing, and protease inhibitors on mediator concentration were evaluated in healthy controls and CF patients, which serve as a model for chronic bacterial infection and inflammation.	24370751
Cessation of life, Inflammation, Fibrosis Assessment, Chronic Kidney Diseases	Altered Intercellular Communication	Biomarkers of inflammation, fibrosis, cardiac stretch and injury predict death but not renal replacement therapy at 1 year in a Canadian chronic kidney disease cohort.	24371297
Inflammation, Fibrosis Assessment, Chronic Kidney Diseases	Altered Intercellular Communication	Newer biomarkers, reflective of biological processes, such as inflammation and fibrosis, cardiac stretch or damage and vascular health may be useful in understanding clinical events in chronic kidney disease (CKD).	24371297
Inflammation, Neoplasms	Altered Intercellular Communication	Interleukin-6 plays an important role in chronic inflammation as well as tumor growth and progression.	24371367
Inflammation, Lymphohistiocytosis, Hemophagocytic	Altered Intercellular Communication	Hemophagocytic lymphohistiocytosis (HLH) is a rare syndrome of extreme inflammation caused by pathologic activation of the immune system.	24371860
Inflammation, Lymphoma, Mucosa-Associated Lymphoid Tissue Lymphoma	Altered Intercellular Communication	Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) comprises 7-8% of B-cell lymphomas and commonly originates from a background of long-standing chronic inflammation.	24372375
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	States of advanced chronic kidney disease and dialysis are associated with a state of chronic inflammation.	24372974
vascular inflammations, Endothelial dysfunction	Altered Intercellular Communication	The effect of aspirin upon platelet function is well documented although experimental studies suggest that aspirin may also affect oxidative stress, vascular inflammation, endothelial dysfunction and dysglycaemia.	24372992
Inflammation, Erosion lesion	Altered Intercellular Communication	The presence of signs of inflammation, bone erosions or rotator cuff pathology was evaluated.	24373322
ARCN1 gene, Inflammation, Inflammatory lung disease	Altered Intercellular Communication	YKL-40 is a potential biomarker of inflammation and mortality in patients suffering from inflammatory lung disease, but its prognostic value in patients with COPD remains unknown.	24373580
Inflammation, physiopathological	Altered Intercellular Communication	Exposure to particulate air pollution increases respiratory and cardiovascular morbidity and mortality, especially in elderly, possibly through inflammation and vascular dysfunction.	24373585
Inflammation, Atherosclerosis	Altered Intercellular Communication	Two main features are involved in the progression of atherosclerosis, lipid retention and inflammation.	24373925
Inflammation, Atherosclerosis	Altered Intercellular Communication	12/15-lipoxygenases are involved in inflammation and have been implicated in atherosclerosis.	24373925
Inflammation, Acute Coronary Syndrome, Depression, CTCAE	Altered Intercellular Communication	Do platelet-derived microparticles play a role in depression, inflammation, and acute coronary syndrome?	24374086
Inflammation	Altered Intercellular Communication	Both abnormal platelet physiology and inflammation have been suggested as potential confounding variables.	24374086
Inflammation, Depression, CTCAE, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	We set out to examine platelet activation, inflammation, and levels of depression in hospitalized patients presenting with ACS.	24374086
Inflammation, Depression, CTCAE, Thrombosis of blood vessel	Altered Intercellular Communication	These results are intriguing in that a potential pathway to explain the connection between depression, inflammation, and increased cardiovascular thrombosis might be found when both platelet activation and inflammation are measured.	24374086
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Fecal hemoglobin and calprotectin are equally effective in identifying patients with inflammatory bowel disease with active endoscopic inflammation.	24374878
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Fecal calprotectin can be used as a noninvasive tool to assess inflammation in patients with inflammatory bowel disease (IBD).	24374878
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	We compared the efficacy of fecal hemoglobin and calprotectin as markers for endoscopic inflammation in patients with IBD.	24374878
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Fecal hemoglobin can identify patients with IBD with active inflammation with a predictive accuracy similar to calprotectin.	24374878
Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	Inflammation plays a role in the pathogenesis of carotid atherosclerosis.	24375839
Inflammation, Nucleolar Fibrillar Material, Congenital bilateral aplasia of vas deferens	Altered Intercellular Communication	While earlier studies demonstrated that alterations in fluid shear stress (FSS) on the fibrosa could trigger inflammation, the mechanisms of CAVD pathogenesis secondary to side-specific FSS abnormalities are poorly understood.	24376809
Polymyositis, Myositis, CTCAE 5.0, Myositis	Altered Intercellular Communication	Although not as common as polymyositis, inclusion body myositis (IBM) is a form of inflammatory myopathy characterized by chronic progressive muscle inflammation and often goes undiagnosed and untreated.	24377075
Inflammation, Fibromyalgia	Altered Intercellular Communication	Metal-induced inflammation triggers fibromyalgia in metal-allergic patients.	24378456
Inflammation, Federated States of Micronesia	Altered Intercellular Communication	This suggests that metal-induced inflammation might be an important risk factor in a subset of patients with FM.	24378456
Inflammation, Pericardial Effusion, CTCAE, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	The presence of pericardial effusion (PE) is considered to be suggestive of inflammation in suspected myocarditis.	24378485
Myocarditis, CTCAE 5.0, AMCN gene, Myocarditis	Altered Intercellular Communication	According to EMB results, PE was found in 86% of patients with AMC, 67% with chronic myocarditis, and 56% without evidence of myocardial inflammation.	24378485
Tissue damage, Inflammation, Inflammatory Bowel Diseases	Altered Intercellular Communication	Matrix metalloproteinases (MMPs), tissue inhibitors of metalloproteinases (TIMPs), a disintegrin and metalloprotease with thrombospondin motifs [ADAM(TS)s] and growth factors are involved in inflammation and tissue damage and repair, all occurring in inflammatory bowel disease (IBD).	24378596
Epithelial Damage, Inflammation	Altered Intercellular Communication	Our data suggest that suppression of inflammation results in the arrest of epithelial damage and subsequent mucosal healing.	24378596
Inflammation, Federated States of Micronesia	Altered Intercellular Communication	The Ex + PLA group showed significant changes in MMI (+0.33 kg/m, P <= 0.009) and FM compartments (waist circumference, -5.13 cm; % FM, -1.31%; P <= 0.001), whereas inflammation remained unchanged.	24378766
Psoriasis, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation contributes to the pathogenesis of psoriasis as well as atrial fibrillation.	24379001
palladium, Inflammation	Altered Intercellular Communication	In the PD group more advanced age had a decisive negative impact on survival whereas in the HD group the outlook was dependent on factors related to nutrition and inflammation.	24379248
Inflammation	Altered Intercellular Communication	These findings support the current concept of chronic Th17-cell mediated inflammation and provide evidence that links the Th17 signatures to ocular-specific immune responses in BSCR.	24379648
Primary malignant neoplasm, Supraventricular Tachycardia by ECG Finding, Unknown (origin) (qualifier value), Abdominal Infection, Liver Cirrhosis	Altered Intercellular Communication	Most common risk factors included cirrhosis (27.8%), solid cancer (22.3%), and intra-abdominal inflammation/infection (11.7%); in 27.4% of patients, SVT was idiopathic.	24381147
vascular inflammations, Restenosis	Altered Intercellular Communication	Greater vascular inflammation after ELA with spot stent resulted in earlier restenosis and inferior 1-year clinical outcomes than primary stenting.	24381515
Gingivitis, Ulcer, Calculi, Tooth structure, Dental Plaque, Alveolar Bone Loss	Altered Intercellular Communication	The clinical examination also showed that there were no statistically significant differences with respect to ulcerations, gingival recession, tooth mobility, gingival inflammation, periodontal bone loss, DMFT/T scores, plaque, and calculus levels.	24382366
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	The agreement between the donor hospital and study pathologists was substantial regarding evaluation of steatosis (k = 0.623) and fibrosis (k = 0.627) and moderate regarding inflammation (k = 0.495).	24382833
Inflammation, Anemia, Sickle Cell	Altered Intercellular Communication	Inflammation, leucocyte and red cell adhesion to the endothelium contribute to the pathogenesis of sickle cell anaemia.	24383847
Inflammation, Coronary Artery Disease, Diabetes Mellitus	Altered Intercellular Communication	The role played by T helper cytokines under chronic, low grade inflammation as seen in type-2 Diabetes Mellitus (T2DM) and Coronary Artery Disease (CAD) co-morbidity is less well studied.	24383855
Fibrosis Assessment, Tubular atrophy, Interstitial inflammation, MPV17 gene	Altered Intercellular Communication	Category 1: Interstitial fibrosis +- mild interstitial inflammation +- tubular atrophy; no glomerulosclerosis.	24385054
Fibrosis Assessment, Tubular atrophy, Interstitial inflammation, MPV17 gene	Altered Intercellular Communication	Category 2: Interstitial fibrosis +- mild interstitial inflammation +- tubular atrophy; glomerulosclerosis.	24385054
Interstitial inflammation, Fibrosis Assessment, Interstitial Fibrosis Assessment, MPV17 gene, Tubular atrophy	Altered Intercellular Communication	Category 3: Moderate or severe interstitial fibrosis, interstitial inflammation and tubular atrophy +- glomerulosclerosis; Category 4: Interstitial inflammation +- tubular atrophy +- glomerulosclerosis; no interstitial fibrosis.	24385054
Tubulitis Assessment, Interstitial inflammation	Altered Intercellular Communication	Category 5: The prominent change is interstitial inflammation with tubulitis.	24385054
Inflammation, Interstitial Fibrosis Assessment	Altered Intercellular Communication	Apart from category 0, all had interstitial fibrosis and in category 1, 62 (87.3%) had interstitial fibrosis without inflammation.	24385054
Interstitial inflammation	Altered Intercellular Communication	Severity of interstitial inflammation increased from category 1 to 3.	24385054
Fibrosis Assessment, Interstitial inflammation, Glomerulosclerosis (disorder)	Altered Intercellular Communication	The early disease among asymptomatic patients is characterized by interstitial fibrosis without significant interstitial inflammation and glomerular sclerosis with preserved glomerular function.	24385054
Interstitial inflammation	Altered Intercellular Communication	Although the role of interstitial inflammation in the initiation of the disease is not clear, it appears to have a role in the progression of the disease.	24385054
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	WNT signaling pathway gene polymorphisms and risk of hepatic fibrosis and inflammation in HCV-infected patients.	24386373
Inflammation, Fibrosis Assessment, Hepatitis C	Altered Intercellular Communication	This study aimed to determine if genetic variation in Wnt signaling pathway genes are associated with advanced hepatic fibrosis and inflammation risk in a hepatitis C virus (HCV) infected population.	24386373
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Among 425 chronically HCV-infected male veterans, 155 (37%) had advanced fibrosis and 180 (42%) had advanced inflammation.	24386373
Fibrosis, Liver, Inflammation	Altered Intercellular Communication	Polymorphisms in several genes involved in the Wnt signaling pathway were associated with hepatic fibrosis or inflammation risk in HCV-infected males.	24386373
Infarction, Acute retention of urine, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	To investigate the roles of prostatic infarction, prostatic inflammation and the type of prostatic hyperplasia in acute urinary retention (AUR) in patients with benign prostatic hyperplasia (BPH).	24386860
Infarction, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	We compared the incidences of prostatic infarction and prostatic inflammation, the types of prostatic hyperplasia, the patients' age, the level of prostate specific antigen (PSA), the prostate volume, and international prostate symptom score (IPSS) between the AUR and non-AUR groups.	24386860
Infarction, prostatitis	Altered Intercellular Communication	The incidence rate of AUR was 5.620 and 2.326 times higher in the BPH patients with prostatic infarction and prostatic inflammation respectively than in those without (P < 0.05).	24386860
Infarction, prostatitis	Altered Intercellular Communication	Prostatic infarction and prostatic inflammation are important risk factors of AUR in BPH patients.	24386860
Inflammation, Helicobacter pylori	Altered Intercellular Communication	Helicobacter pylori colonization of the gastric epithelium induces interleukin-8 (IL-8) production and inflammation leading to host cell damage.	24387083
Helicobacter pylori, Gastritis	Altered Intercellular Communication	Strain LP-XB7 contributed to a delay in the detection and colonization of H. pylori in rat stomachs, attenuated gastric inflammation, and ameliorated gastric histopathology.	24387083
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	These results suggest that L. plantarum XB7 produces secreted factors capable of modulating inflammation during H. pylori infection, and this probiotic Lactobacillus strain shows promise as an adjunctive therapy for treating H. pylori-associated disease.	24387083
Heart failure	Altered Intercellular Communication	Short-term changes of neurohormones can give important prognostic information in heart failure (HF) patients.	24388546
Inflammation, Obesity, Abdominal	Altered Intercellular Communication	Strong associations were found with systemic inflammation, abdominal obesity, and LV mass.	24388804
Sleep-Disordered Breathing, Inflammation, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	There are a few established risk factors but a number of further risk factors have been suggested including obesity, metabolic syndrome, sleep-disordered breathing, and inflammation.	24389686
Glucose Metabolism Disorders, Inflammation, Sleep-Disordered Breathing	Altered Intercellular Communication	However, recently suggested potential novel risk factors for AF (inflammation, sleep-disordered breathing, glucose/metabolic disorders) were not confirmed in this study.	24389686
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is fundamental to the development of atherosclerosis.	24390146
Tuberculosis, Pulmonary, Intraocular inflammation, "cytidylyl-(3-5)-cytidine	Altered Intercellular Communication	There was no exacerbation of intraocular inflammation, no postoperative hypotony and no phthisis bulbi in the 16 patients who underwent CPC.	24390401
Inflammation, Synovitis, Refractory anemias, Edema of bone marrow, Enthesitis	Altered Intercellular Communication	The aim of this study was to investigate the ability of whole-body MRI (WBMRI) to visualize inflammation [synovitis, bone marrow oedema (BME) and enthesitis] and structural damage in patients with RA.	24390938
Inflammation, Superficial ulcer, Peripheral, Synovitis, Enthesitis	Altered Intercellular Communication	Short Tau Inversion Recovery and pre- and post-contrast T1-weighted images were evaluated for readability and the presence/absence of inflammation (synovitis, BME and enthesitis) and structural damage (erosions and fat infiltrations) in 76 peripheral joints, 30 entheseal sites and in the spine.	24390938
Inflammation	Altered Intercellular Communication	Peripheral and axial inflammation and structural damage at joints and entheses was frequently identified by WBMRI, and more frequently than by clinical examination.	24390938
Refractory anemias, Inflammation	Altered Intercellular Communication	WBMRI is a promising tool for evaluation of the total inflammatory load of inflammation (an MRI joint count) and structural damage in RA patients.	24390938
Gastrointestinal inflammation	Altered Intercellular Communication	Macrophages regulate innate immunity to maintain intestinal homeostasis and play pathological roles in intestinal inflammation.	24391216
Gastrointestinal inflammation	Altered Intercellular Communication	This study was to investigate whether EGFR activation in macrophages regulates cytokine production and intestinal inflammation.	24391216
Gastrointestinal inflammation	Altered Intercellular Communication	Thus, although selective deletion of EGFR in macrophages leads to increases in both pro- and anti-inflammatory cytokines in response to inflammatory stimuli, the increase in the IL-10 level plays a role in suppressing proinflammatory cytokine production, resulting in protection of mice from intestinal inflammation.	24391216
Inflammation, Cardiomyopathies, Myocarditis, CTCAE 5.0, Influenza-like symptoms, Juvenile rheumatoid arthritis	Altered Intercellular Communication	A 20-year-old pregnant woman with a history of juvenile idiopathic arthritis presented with flu-like symptoms, systemic inflammation with myocarditis, and severe cardiomyopathy.	24391342
Malignant neoplasm of urinary bladder, Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	The relationship between inflammation and cancer is well established in several tumor types, including bladder cancer.	24391818
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	CHRNA7 encodes the a7 nicotinic acetylcholine receptor subunit, which is important to Alzheimer's disease (AD) pathogenesis and cholinergic neurotransmission.	24391883
Inflammation	Altered Intercellular Communication	Additionally, vascular function was associated with inflammatory markers, suggesting that the favourable influence of physical activity may be mediated by its effect on inflammation.	24392783
Inflammation, Epithelial	Altered Intercellular Communication	Salmeterol reduced some biomarkers of alveolar inflammation and epithelial injury.	24392848
Intraocular inflammation	Altered Intercellular Communication	Relationship between suspected reasons of intraocular inflammation and the results of diagnostic vitrectomy: an observational study.	24392961
Communicable Diseases, Inflammation, Inflammatory disorder	Altered Intercellular Communication	Intraocular inflammation of the posterior segment may be associated with neoplastic, infectious, and inflammatory diseases.	24392961
Intraocular inflammation	Altered Intercellular Communication	We therefore aimed to investigate the safety and usefulness of diagnostic vitrectomy in intraocular inflammation.	24392961
Inflammation	Altered Intercellular Communication	We hypothesized a strong association between HR at rest and subclinical inflammation, given their common interrelation with the autonomic nervous system.	24393259
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	In conclusion, an increased HR at rest was associated with a higher level of inflammation among an ethnically diverse group of subjects without known cardiovascular disease.	24393259
Inflammation	Altered Intercellular Communication	Mucosa-associated lymphoid tissue (MALT) lymphoma usually arises from chronic inflammation.	24395281
Inflammation, Blind Loop Syndrome	Altered Intercellular Communication	Gastrointestinal reconstruction may be responsible for underlying chronic inflammation via small intestinal bacterial overgrowth.	24395281
Slovenia, glycation, Inflammation, Diabetic Neuropathies	Altered Intercellular Communication	We asked whether the receptor of advanced glycation end products (RAGE) is related to dermal inflammation in nonsystemic vasculitic neuropathy (NSVN) and diabetic neuropathy (DN) and whether its presence in skin is comparable to that in sural nerve biopsies.	24395344
Inflammation	Altered Intercellular Communication	Dermal RAGE is increased in NSVN and DN, supporting the concept of a role of the RAGE pathway in the pathophysiology of dermal inflammation and skin denervation in NSVN and DN.	24395344
Inflammation, Atrophy of mucosa of stomach, Autoimmune Atrophic Chronic Gastritis	Altered Intercellular Communication	Atrophic autoimmune gastritis (AAG) is a condition of chronic inflammation and atrophy of stomach mucosa, for which development can be partially triggered by the bacterial pathogen Helicobacter pylori (HP).	24395566
Inflammation, Sensorineural Hearing Loss (disorder), Cholangitis, Facial paralysis	Altered Intercellular Communication	The conclusion is that sensorineural hearing loss and facial palsy in patients with MPO-ANCA related angitis occurred due to strong inflammation in the cochlea or facial nerve.	24397116
Rupture, Athletic Injuries, Inflammation, Hyaline degeneration, Necrosis, Giant Cell Tumors, Structure of achilles tendon	Altered Intercellular Communication	Of 9 cases, 6 were male and 3 were female with an average age of 43 years (range, 21-65 years), including 5 cases of chronic Achilles tendon ruptures caused by sport injury and 4 cases of Achilles tendon defects caused by resection of tendon lesion (2 cases of hyaline degeneration with necrosis, 1 case of giant cell tumor, and 1 case of chronic inflammation with hyaline degeneration).	24397131
Inflammation, Asthma	Altered Intercellular Communication	Aeroallergen and food IgE sensitization and local and systemic inflammation in asthma.	24397423
Airway structure, Sensitization (observable entity)	Altered Intercellular Communication	We recently reported an independent association between IgE sensitization to food allergens and increased airway inflammation, assessed by fraction of exhaled nitric oxide (FeNO), in a population-based study (J Allergy Clin Immunol, 130, 2012, 397).	24397423
Inflammation, Asthma, Sensitization (observable entity)	Altered Intercellular Communication	Independent effects of IgE sensitization to aeroallergens (furry animals and mould) and food allergens were found on both local and systemic markers of inflammation in asthma.	24397423
Inflammation, Asthma	Altered Intercellular Communication	The finding regarding food IgE sensitization is novel, and a clinical implication might be that even food sensitization must be assessed to fully understand inflammation patterns in asthma.	24397423
Inflammation, Atherosclerosis	Altered Intercellular Communication	Using MAP, several low abundance proteins implicated in atherosclerosis and inflammation were found on HDL.	24397693
Inflammation, Thrombosis, Angiogenic Process	Altered Intercellular Communication	Ramipril is associated with an increase in the biomarkers of angiogenesis/arteriogenesis and reduction in the markers of thrombosis, inflammation, and leukocyte adhesion.	24397981
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ultrasound biomicroscopy in chronic pseudophakic ocular inflammation associated with misplaced intraocular lens haptics.	24398393
Inflammation, Damage, Chemical injury	Altered Intercellular Communication	Results of all the nerve biopsies were abnormal, showing axonal damage (7 patients), inflammation (7 patients), signs of ischemic injury (7 patients), and nerve microvasculitis (6 patients).	24398433
Inflammation, Atherosclerosis	Altered Intercellular Communication	Liver X receptors (LXRs) are nuclear receptors whose activation protects against atherosclerosis by transcriptional regulation of genes important in promoting cholesterol efflux and inhibiting inflammation.	24398515
Inflammation	Altered Intercellular Communication	These needle-like crystals induce not only acute episodes of inflammatory process into the surrounding area, but also, in the long-term history of the disease, chronic inflammation that is associated with changes in articular and periarticular structures.	24399012
Inflammation, Neoplasms, Autoimmune Diseases, Unknown (origin) (qualifier value), Pachymeningitis	Altered Intercellular Communication	Pachymeningitis is a progressive disease resulting in a diffuse thickening of dura mater due to inflammation, tumor or autoimmune diseases, but most cases are idiopathic.	24399188
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Serum irisin levels were quantified by ELISA and correlated with anthropometric and biochemical parameters of renal function, glucose and lipid metabolism, as well as inflammation, in 532 patients with stages 1-5 of chronic kidney disease (CKD).	24399249
Inflammation, One Vessel Coronary Disease	Altered Intercellular Communication	Inflammation is a prominent pathological feature of small vessel disease.	24399375
PVR wt Allele, Inflammation	Altered Intercellular Communication	We examined the association between inflammation, PVS, and WMH in the Lothian Birth Cohort 1936 (N=634).	24399375
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	After accounting for age, sex, stroke, and vascular risk factors, PVS were significantly associated with WMH (b=0.47; P<0.0001); Inflammation was weakly but significantly associated with PVS (b=0.12; P=0.048), but not with WMH (b=0.02; P=NS).	24399375
Inflammation, One Vessel Coronary Disease	Altered Intercellular Communication	Longitudinal studies should examine whether visible PVS predate WMH progression and whether inflammation modulators can prevent small vessel disease.	24399375
Inflammation, Abdominal Pain, Hyponatremia	Altered Intercellular Communication	A 41-year-old woman, suffering from continuous abdominal pain, only presented a non-specific inflammation of the whole colon and an unclaryfied hyponatriaemia; in spite of the only doubtful explanation by an enormous elongation of the colon, it was partially resected.	24399476
Inflammation	Altered Intercellular Communication	Human butyrylcholinesterase (BuChE) and paraoxonase-1 (PON1) are two major bioscavenger enzymes that are associated with inflammation, oxidative stress and lipid metabolism.	24399815
Neurogenic Inflammation, Trigeminal nerve structure	Altered Intercellular Communication	It represents a unique proof of principle in that not only trigeminal nerve pain but also presumed neurogenic inflammation can be relieved by blockade of cervical nociceptive inputs.	24401103
Autoimmune Diseases, Inflammation, Dermatomyositis, Childhood Type	Altered Intercellular Communication	Juvenile dermatomyositis is a rare autoimmune disease that causes inflammation of the skin and muscles.	24401174
Inflammation, HIV Infections, Cardiovascular Diseases	Altered Intercellular Communication	HIV infection causes systemic immune inflammation, and increases the risk for cardiovascular (CVD) disease even among those on virologically suppressive anti-retroviral treatment (ART).	24401216
Intestinal metaplasia of gastric mucosa, Inflammation, Gastritis, Gastritis, Atrophic, Chronic gastritis	Altered Intercellular Communication	Among H pylori-positive participants, prevalence was 94% for acute gastritis, 100% for chronic gastritis, 21% for gastric atrophy and 11% for intestinal metaplasia of the gastric mucosa, while chronic inflammation severity was mild in 9%, moderate in 47% and severe in 43%.	24401722
Airway structure, Asthma, IL13 gene, Cerebrovascular accident	Altered Intercellular Communication	Perennial allergic rhinitis may be relevant for CVA patients as well as classic asthma patients by consistently augmenting eosinophilic lower airway inflammation.	24401902
Inflammation, Primary malignant neoplasm, Cachexia	Altered Intercellular Communication	Systemic inflammation contributes to both the development of cancer and of cachexia.	24402361
Inflammation, Low muscle mass, Endothelial dysfunction	Altered Intercellular Communication	Increasing physical activity, consuming a diet with a high proportion of energy from carbohydrates, and taking steps to prevent insulin resistance and reduce inflammation and endothelial dysfunction may help to reduce the risk of low muscle mass in older men.	24402385
Sleep Apnea, Obstructive	Altered Intercellular Communication	Abstract Inflammation plays a critical role in the pathogenesis of obstructive sleep apnea syndrome (OSAS).	24405178
Juvenile arthritis, Inflammation, Uveitis	Altered Intercellular Communication	Children with JIA are at risk of inflammation of the uvea in the eye (uveitis).	24405833
Inflammation, Uveitis	Altered Intercellular Communication	In the initial stages of mild to moderate inflammation the uveitis is asymptomatic.	24405833
HD Term Type, Inflammation	Altered Intercellular Communication	Inflammation and glycemic control are important prognosis-related factors for hemodialysis (HD) patients; moreover, inflammation affects insulin secretion.	24405885
Inflammation, Endothelium	Altered Intercellular Communication	Glomerular inflammation correlates with endothelial injury, monocyte influx, and IL-6 and IL-b secretion by circulating immune cells.	24406453
Inflammation, Comorbidity	Altered Intercellular Communication	Analyses were adjusted for demographics measures, disease severity indicators, inflammation, comorbidity and medication.	24407045
Cessation of life, Sepsis, Multiple Organ Failure, Inflammation	Altered Intercellular Communication	Death from sepsis in the intensive care unit (ITU) is frequently preceded by the development of multiple organ failure as a result of uncontrolled inflammation.	24408035
Coronary artery ectasia, Inflammation, CDE protocol-cyclophosphamide/doxorubicin/etoposide	Altered Intercellular Communication	Previous studies have demonstrated that inflammation, neurohormonal process and cardiovascular risk factors are associated with the development of coronary artery ectasia (CAE).	24408063
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The neutrophil to lymphocyte (N/L) ratio has recently emerged as a new inflammation marker for cardiovascular disease.	24408063
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	In this study, we hypothesised that CAE could be associated with more severe inflammation compared to obstructive coronary artery disease (O-CAD) with regard to N/L ratio values.	24408063
Inflammation, Subarachnoid Hemorrhage	Altered Intercellular Communication	ADMA levels and arginine/ADMA ratios reflect severity of disease and extent of inflammation after subarachnoid hemorrhage.	24408146
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	This might indicate that endothelial dysfunction, with ADMA as a marker, is induced by a systemic inflammation.	24408146
Cessation of life, Coronary Aneurysm, Inflammation, Myocardial Ischemia	Altered Intercellular Communication	We report an autopsy case of a coronary aneurysm with massive adventitial inflammation post-percutaneous coronary intervention with sirolimus-eluting stent (SES) insertion in the left circumflex (LCX) coronary artery for ischemic heart disease 3 years prior to death.	24408671
Coronary Aneurysm, Inflammation	Altered Intercellular Communication	Chronic inflammation can lead to the development of coronary artery aneurysms.	24408671
Inflammation	Altered Intercellular Communication	Furthermore, significantly high-grade inflammation and evidence of active H. pylori-induced gastritis was observed in the "DWP" type (P < 0.001).	24409067
Inflammation, Gastritis	Altered Intercellular Communication	CO whiteness detected via ME was associated with histological evidence of gastritis and helps to predict the severity of inflammation and H. pylori-induced activity.	24409067
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	An inflammation based score can optimize the selection of patients with advanced cancer considered for early phase clinical trials.	24409281
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	As inflammation is pathogenic and prognostic in cancer we investigated the prognostic performance of inflammation-based indices including the neutrophil (NLR) and platelet to lymphocyte ratio (PLR).	24409281
Inflammation	Altered Intercellular Communication	UVA rays present in sunlight are able to reach the dermal skin layer generating reactive oxygen species (ROS) responsible for oxidative damage, alterations in gene expression, DNA damage, leading to cell inflammation, photo-ageing/-carcinogenesis.	24409282
Communicable Diseases, Inflammation	Altered Intercellular Communication	Calcium binding-mediated sustained release of minocycline from hydrophilic multilayer coatings targeting infection and inflammation.	24409292
Communicable Diseases, Inflammation	Altered Intercellular Communication	Infection and inflammation are common complications that seriously affect the functionality and longevity of implanted medical implants.	24409292
Communicable Diseases, Acidosis	Altered Intercellular Communication	pH-responsive minocycline release was observed as the chelation between minocycline and Ca(2+) is less stable at acidic pH, enabling 'smart' drug delivery in response to infection and/or inflammation-induced tissue acidosis.	24409292
Inflammation, Psoriasis, Dyslipidemias, Coronary heart disease, Diabetes Mellitus, Psoriatic Juvenile Idiopathic Arthritis, Hypertension, CTCAE	Altered Intercellular Communication	Psoriatic patients have significantly greater risks of developing coronary heart disease than controls in relationship with psoriasis comorbidities such as hypertension, diabetes, dyslipidemia, inflammation and probably with psoriasis itself.	24409658
Inflammation, Periodontitis, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Serum C-reactive protein (CRP) is elevated in both periodontitis and type 2 diabetes mellitus through inflammation.	24410292
palladium, Inflammation, Periodontitis, Hyperglycemia	Altered Intercellular Communication	Logistic regression models with survey procedures were used to explore the roles of inflammation levels from serum CRP and periodontal pathogens on the relations with periodontitis, including PD, CAL, and hyperglycemia, and their joint associations with interaction terms.	24410292
Periodontitis	Altered Intercellular Communication	This may suggest that chronic inflammatory conditions could increase the impact of periodontitis on hyperglycemic status.	24410292
Inflammation, Gangrene, Perforation (observation), Specimen Source Codes - Abscess	Altered Intercellular Communication	The degree of inflammation of the resected specimens was grossly assessed and graded into acute inflammation, acute inflammation with complications (such as gangrene, perforation, abscess) and un-inflamed appendix.	24411549
Inflammation, Retinitis Pigmentosa, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	We assessed the association between RP and white blood cell (WBC) count, an established metric of systemic inflammation, after RT for non-small cell lung cancer.	24411603
Inflammation, Superficial ulcer	Altered Intercellular Communication	At diagnosis, colonoscopy showed modest inflammation and few superficial ulcerations and erosions in the ileo-cecal valve and the terminal ileum.	24411923
Inflammation, Dental Plaque, Atherosclerotic lesion	Altered Intercellular Communication	The integrin avb3 is expressed by macrophages and angiogenic endothelial cells in atherosclerotic lesions and thus is a marker of plaque inflammation and, potentially, of plaque vulnerability.	24412187
Inflammation	Altered Intercellular Communication	Based on these initial data, larger prospective studies are now warranted to evaluate the potential of molecular imaging of avb3 expression for assessment of plaque inflammation in patients.	24412187
Traumatic injury	Altered Intercellular Communication	Laboratory of Inflammation Biology and Surgical Science and multi-institution level 1 trauma centers.	24413577
Single organ dysfunction, Inflammation, Bacterial Infections	Altered Intercellular Communication	Correlation analyses revealed significant correlations of miR-133a with disease severity, classical markers of inflammation and bacterial infection, and organ failure.	24413579
Intraocular inflammation, Uveitis	Altered Intercellular Communication	Examination revealed an anterior uveitis and despite an initial response to topical steroids, the intraocular inflammation worsened with anterior and posterior uveitis development.	24413827
Intraocular inflammation	Altered Intercellular Communication	After improvement and tapering of this treatment, the intraocular inflammation reoccurred.	24413827
Fibrosis Assessment, Mucocele of appendix	Altered Intercellular Communication	In asymptomatic patients without appendiceal inflammation, the appendix can be dilated by intraluminal material such as inspissated succus in cystic fibrosis or mucus from benign appendiceal mucocele.	24414145
Appendicitis, CTCAE, Pathology	Altered Intercellular Communication	Attention to mural features, cecal configuration, and periappendiceal inflammation is essential to the correct prospective diagnosis of complicated appendicitis and less common appendiceal pathologies.	24414145
Inflammation, Cerebral Ischemia	Altered Intercellular Communication	Cerebral ischemia triggers a cascade of cellular processes, which induce neuroprotection, inflammation, apoptosis and regeneration.	24415059
Inflammation, Chronic Kidney Insufficiency, Chronic Kidney Diseases	Altered Intercellular Communication	Race modifies the association between adiposity and inflammation in patients with chronic kidney disease: findings from the chronic renal insufficiency cohort study.	24415732
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The race-specific association of inflammation with adiposity and muscle mass in subjects with chronic kidney disease (CKD) was examined.	24415732
Inflammation, ABCA4 gene	Altered Intercellular Communication	Race stratified analysis showed that the association between biomarkers and BFM and FFM differed by race, with Caucasians, demonstrating a stronger association with markers of inflammation than African Americans.	24415732
Inflammation, ABCA4 gene, Chronic Kidney Diseases	Altered Intercellular Communication	BFA and FFM are positively associated with markers of inflammation in patients with CKD.	24415732
Inflammation	Altered Intercellular Communication	Race stratified analysis showed that Caucasians have a stronger association with markers of inflammation compared to African Americans.	24415732
Inflammation	Altered Intercellular Communication	The reciprocal regulation between Del-1 and inflammation may contribute to optimally balance the protective and the potentially harmful effects of inflammatory cell recruitment.	24416060
Inflammation, Merkel cell carcinoma, Merkel cell polyomavirus	Altered Intercellular Communication	PD-L1 expression in the Merkel cell carcinoma microenvironment: association with inflammation, Merkel cell polyomavirus and overall survival.	24416729
Inflammation, Progranulins, Obesity	Altered Intercellular Communication	C1q/TNF-related protein-3 (CTRP-3), an adiponectin paralog, and progranulin were recently identified as novel adipokines which may link obesity with glucose dysregulation and subclinical inflammation.	24417980
Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	The immune response plays an unsettled role in the pathogenesis of idiopathic pulmonary fibrosis (IPF), the contribution of inflammation being controversial as well.	24418172
Communicable Diseases, Inflammation	Altered Intercellular Communication	At an age when infection, inflammation and airway wall remodeling are minimal, neonates with CF had an acidic nasal ASL compared to babies without CF.	24418186
Inflammation, Duodenal villous atrophy, Crypt	Altered Intercellular Communication	In the duodenal mucosa, total or subtotal duodenal villous atrophy, inflammation, crypt distortion, and increased apoptotic bodies were the most common features.	24418855
methyldopa, Inflammation, Visual Impairment, Blindness	Altered Intercellular Communication	Age-related macular degeneration (AMD) is the leading cause of irreversible visual impairment and blindness among persons aged 60 years and older and many theories exist and feature mechanisms of oxidative stress, atherosclerotic-like changes, genetic predisposition, and inflammation in development of AMD.	24418867
methyldopa, Inflammation, Atherosclerosis	Altered Intercellular Communication	Our data support the role of chronic inflammation in the development of AMD, however, further studies are needed to determine which common disease mechanisms of chronic inflammation and atherosclerosis contribute to the pathogenesis of AMD.	24418867
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Pleural biopsies were obtained through medical pleuroscopy that revealed mild chronic inflammation with prominent eosinophils and no evidence for malignancy.	24419196
Inflammation	Altered Intercellular Communication	The elevation of serum CEA might be attributed to the presence of local inflammation in the lung.	24419710
Inflammation, Fibrosis Assessment, FBN2 wt Allele, Infestation	Altered Intercellular Communication	Ov infestation caused chronic inflammation of the biliary tree by periductal fibrosis (PDF), which may subsequently lead to CCA development.	24420706
Injury of kidney	Altered Intercellular Communication	Transcriptional repressor activating transcription factor 3 (ATF3) is induced by various stress stimuli, including inflammation-induced renal injury.	24420912
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver and white adipose tissue (WAT) develop inflammation and fibrosis.	24423338
Inflammation	Altered Intercellular Communication	Knowledge about the interrelationship between adiposity and systemic low-grade inflammation during pubertal growth is important in detecting early signs of obesity-related metabolic disorders.	24423339
Inflammation	Altered Intercellular Communication	FM explained the variance of hsCRP during pubertal growth, but the reverse was not true, which suggests that FM contributes to low-grade inflammation and not vice versa.	24423339
ARCN1 gene, Colonization, Airway structure	Altered Intercellular Communication	Even in the absence of clinical exacerbation, colonization by bacterial pathogens in COPD was associated with a clinically significant moderate increase in daily symptoms, likely mediated by increased airway inflammation.	24423399
Inflammation, Atherosclerosis	Altered Intercellular Communication	Physical activity can prevent and/or attenuate atherosclerosis, a disease clearly linked to inflammation.	24423463
Inflammation	Altered Intercellular Communication	Discovery of molecular pathways mediating 1,25-dihydroxyvitamin D3 protection against cytokine-induced inflammation and damage of human and male mouse islets of Langerhans.	24424042
therapeutic hemodilution	Altered Intercellular Communication	CEA may be affected in obese individuals by several factors, including but not limiting to hemodilution, inflammatory conditions, and insulin resistance.	24425143
methyldopa, Age related macular degeneration	Altered Intercellular Communication	Oxidant- and inflammation-induced damage to retinal pigment epithelial (RPE) cells is central to the pathogenesis of age-related macular degeneration (AMD).	24426777
methyldopa, Inflammation	Altered Intercellular Communication	Given the crucial causative roles of oxidative stress and inflammation in AMD pathogenesis, knowing whether OTC might exhibit a similar benefit in this cell and tissue type has high clinical relevance; thus, we evaluated OTC in the present study.	24426777
Inflammation, Xanthomatosis	Altered Intercellular Communication	To provide further insights into the pathophysiology of NXG, we evaluated the plasma lipid phenotype, mechanisms involved in cellular cholesterol accumulation and role of MIg in an analysis of blood and plasma markers of inflammation in 16 patients with xanthomatosis [NXG (n = 8) and NX (n = 8)] associated with monoclonal IgG relative to the relevant controls.	24428816
Inflammation, Glomerulonephritis	Altered Intercellular Communication	Patients with ANCA-associated glomerulonephritis had significantly higher levels of suPAR compared with the other disease groups, which may be owing to their lower renal function and systemic inflammation.	24429394
Inflammation, Dysbiosis	Altered Intercellular Communication	It is unlikely that a single bacterium perpetuates inflammation in late stage CD; dysbiosis was common and we found no evidence of increased bacterial translocation.	24429583
Aphthous Stomatitis, Inflammation, Granuloma	Altered Intercellular Communication	We believe that future studies should focus on early disease and viable bacteria in nodes, aphthous ulcers and granulomas, as they may be more relevant in the initiation of inflammation in CD.	24429583
Inflammation, Microbleeds	Altered Intercellular Communication	T2-based imaging showed microbleeds and analysis of the apolipoprotein E (ApoE) genotype showed e4/e4; therefore, cerebral amyloid angiopathy-related inflammation was diagnosed.	24429648
ARCN1 gene, Inflammation	Altered Intercellular Communication	In models of COPD, environmental stressors induce innate immune responses, inflammasome activation and inflammation.	24430176
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	However, the interaction between these responses and their role in driving pulmonary inflammation in stable COPD is unknown.	24430176
Inflammation	Altered Intercellular Communication	Data on MRI inflammation were compared with clinical inflammation and baseline radiological erosions.	24431393
Superficial ulcer, Inflammation, Anti-Citrullinated Protein Antibodies, Trauma, Nervous System, Rheumatoid Factor	Altered Intercellular Communication	Baseline erosions were an independent predictor and not a mediator between symptom duration, systemic or local clinical inflammation (erythrocyte sedimentation rate (ESR), swollen joint count (SJC)) or autoantibodies (anti-citrullinated-peptide antibodies, rheumatoid factor) and radiological damage.	24431393
Inflammation, Superficial ulcer	Altered Intercellular Communication	Subclinical MRI inflammation was studied in relation to erosions, revealing that 83% of the non-swollen joints with baseline erosions had subclinical MRI inflammation compared with 25% of the non-swollen joints without baseline erosions (OR 15.2 95% CI 3.1 to 102.1).	24431393
Inflammation, Superficial ulcer	Altered Intercellular Communication	The association between MRI inflammation and baseline erosions was independent of symptom duration, ESR, SJC and autoantibodies.	24431393
Superficial ulcer, Damage, Inflammation	Altered Intercellular Communication	Baseline erosions are a predictor for future joint damage, independent of known predictors as time, autoantibodies or clinical measurable inflammation.	24431393
Inflammation	Altered Intercellular Communication	Subclinical inflammation is suggested as an underlying mechanism.	24431393
Communicable Diseases, Inflammation	Altered Intercellular Communication	Interleukin-1 (IL-1) is a cytokine critical to inflammation, immunological activation, response to infection, and bone marrow hematopoiesis.	24433038
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	The additive impact of periodic limb movements during sleep on inflammation in patients with obstructive sleep apnea.	24433139
Inflammation, Sleep Apnea, Obstructive, Sleep Disorders, Osage language	Altered Intercellular Communication	Both periodic limb movements during sleep (PLMS) and obstructive sleep apnea (OSA) are major causes of sleep disorders and have been associated with systemic inflammation and cardiovascular events.	24433139
Inflammation, Osage language	Altered Intercellular Communication	To investigate whether the presence of PLMS is associated with increased inflammation in patients suspected of having OSA.	24433139
Kidney Failure, Chronic, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Patients with end-stage renal disease (ESRD) are at an increased risk of cardiovascular disease due to many factors including inflammation and oxidative stress.	24434384
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD), low lung function independent of diagnosis and markers of inflammation are all associated with increased morbidity and mortality.	24435009
ETV3 wt Allele, Large prostate, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	In conclusion, in males of infertile couples, MetS is positively associated with prostate enlargement, biochemical (sIL8) and ultrasound-derived signs of prostate inflammation but not with prostate-related symptoms, which suggests that MetS is a trigger for a subclinical, early-onset form of benign prostatic hyperplasia.	24435050
Inflammation, Community acquired pneumonia	Altered Intercellular Communication	Bedside monitoring of ventilation distribution and alveolar inflammation in community-acquired pneumonia.	24435618
Pneumonitis	Altered Intercellular Communication	FENO could be a prospective supplementary tool to describe local lung inflammation as individual trend parameter.	24435618
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Serum prostate specific antigen (PSA) may be elevated in otherwise healthy men; systemic inflammation has been associated with cancer.	24435840
Inflammation, Prostatic Diseases	Altered Intercellular Communication	Markers of systemic inflammation were associated with elevated PSA in men without known prostatic disease.	24435840
Malnutrition	Altered Intercellular Communication	Malnutrition inflammation score at 6 months (P = .006) and erythropoietin (EPO) dose requirements were higher in the CON group (P = .012).	24436491
ARCN1 gene, Inflammation, physiopathological	Altered Intercellular Communication	Inactivity and systemic inflammation could play a role in the development of limb muscle dysfunction in COPD.	24438094
ARCN1 gene, Inflammation, physiopathological	Altered Intercellular Communication	The reduced level of daily activities and evidence of systemic inflammation in these individuals suggest that these factors precede the development of overt limb muscle dysfunction in COPD.	24438094
Crohn Disease, Inflammation	Altered Intercellular Communication	We examined the outcomes of consecutively performed laparoscopic-assisted ileocecectomy for Crohn's disease (CD), with particular focus on FT's effects in patients with underlying bowel inflammation.	24439590
Choroiditis	Altered Intercellular Communication	All 7 specimens displayed persistent choroidal inflammation, in 1 case 208 days after injection.	24439760
Retinal Detachment, Inflammation, Fibrous	Altered Intercellular Communication	Although no organisms were identified in the examined tissues, persistent inflammation was present in all cases, and fibrous proliferation resulted in cyclitic membrane formation and retinal detachment in all enucleated globes.	24439760
Inflammation	Altered Intercellular Communication	These findings suggest that potential globe-salvaging interventions must address a pattern of changes involving persistent, chronic inflammation and fibrovascular proliferation as key components.	24439760
Inflammation, Diabetes Mellitus, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Kidney donors comprise a highly screened population without risk factors such as diabetes and inflammation, which invariably confound the association between CKD and cardiovascular disease.	24439974
Airway structure, Cystic Fibrosis, Destruction (action)	Altered Intercellular Communication	Airway inflammation, mediated in part by LTB4, contributes to lung destruction in patients with cystic fibrosis (CF).	24440167
Airway structure	Altered Intercellular Communication	LTB(4)-receptor inhibition may reduce airway inflammation.	24440167
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	Studies about inflammation on percutaneous transluminal angioplasty with stent (PTA/stent) to treat peripheral arterial disease (PAD) in humans are scarce.	24440188
Communicable Diseases, Inflammation	Altered Intercellular Communication	Chronic cytomegalovirus (CMV) infection may contribute significantly to T-cell immunosenescence, chronic inflammation, and adverse health outcomes in older adults.	24440388
Inflammation, Defense, Certified Midwife	Altered Intercellular Communication	Host defense defects in the HBV-infected group may lead to a lower intensity of inflammation in the pathogenesis of CM compared with the HBV-uninfected patients and may account for these divergences between the two groups.	24440644
Inflammation, Fibrosis Assessment, Biliary cirrhosis, Liver Failure	Altered Intercellular Communication	It is characterized by progressive inflammation and fibrosis of the bile ducts leading to biliary cirrhosis and eventually liver failure.	24440929
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Subunits of calprotectin, a fecal marker of inflammation in inflammatory bowel disease, have been recently identified in bile.	24440929
Pharyngitis	Altered Intercellular Communication	Moreover, the expression rates of integrin av protein in NPC tissues was 76.92%, significantly higher than that of nasopharyngeal inflammation tissues (6.25%, P< 0.05).	24440971
Sprue, Inflammation	Altered Intercellular Communication	Histologic findings suggesting tropical sprue in the appropriate clinical context include incomplete duodenal villous blunting without development of flat mucosa, frequent involvement of the terminal ileum with more marked inflammation and villous blunting than in the duodenum, and a conspicuous eosinophil infiltrate in the lamina propria.	24441659
Inflammation, Carcinoma, Ulcerative Colitis, Granulomatous inflammation, Neoplastic Polyp, Non-Neoplastic Disorder	Altered Intercellular Communication	Out of 126 colonoscopic biopsies 34(27%) showed chronic nonspecific inflammation, followed by carcinoma 25(19.8%), non-neoplastic polyps 21(16.7%), granulomatous inflammation 14(11.1%), neoplastic polyps 8(6.3%), ulcerative colitis 4(3.2%).	24442164
Inflammation, Aggressive behavior, Hyperplasia	Altered Intercellular Communication	There were no features to suggest a reactive hyperplasia in response to inflammation or of aggressive behaviour.	24442176
Inflammation, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	There is evidence that the link between obesity and cardiovascular disease might relate to inflammation in both fat tissue and the arterial wall.	24442596
Vasculitis	Altered Intercellular Communication	(18)F-FDG uptake on PET is a surrogate marker of vessel wall inflammation.	24442596
Steatitis	Altered Intercellular Communication	Increasing body weight significantly predicted the level of fatty inflammation.	24442596
Increased insulin level, Inflammation, Malignant neoplasm of liver, Obesity, FAM126A gene	Altered Intercellular Communication	Elevated levels of biomarkers of inflammation and hyperinsulinemia are associated with a higher risk of HCC, independent of obesity and established liver cancer risk factors.	24443059
Inflammation, Adenoma of large intestine	Altered Intercellular Communication	Oxidative balance score, colorectal adenoma, and markers of oxidative stress and inflammation.	24443405
Sepsis, Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Inflammation and coagulation are closely interrelated pathophysiologic processes in the pathogenesis of sepsis.	24443891
Malignant Lesion, Nodular fasciitis	Altered Intercellular Communication	Nodular fasciitis is a rare and benign inflammatory condition; however, it can be misdiagnosed as a malignant lesion.	24445897
Inflammation, Atrial Fibrillation by ECG Finding, myocardial injury	Altered Intercellular Communication	Time course of inflammation, myocardial injury, and prothrombotic response after radiofrequency catheter ablation for atrial fibrillation.	24446024
Inflammation, Atrial Fibrillation by ECG Finding, Cerebrovascular accident, Atrial Fibrillation, Cardiac Arrhythmia	Altered Intercellular Communication	Inflammation has been linked to the genesis of stroke in atrial fibrillation (AF) and is implicated in early recurrent arrhythmia after AF ablation.	24446024
Inflammation, Atrial Fibrillation, myocardial injury	Altered Intercellular Communication	We aimed to define the time course of inflammation, myocardial injury, and prothrombotic markers after radiofrequency ablation for AF and its relation to AF recurrence.	24446024
Inflammation, Chronic disease	Altered Intercellular Communication	Inflammation is an important contributor to the development of chronic diseases.	24447090
Inflammation, Noncommunicable Diseases, Aortitis	Altered Intercellular Communication	To identify the frequency of immunoglobulin G4 (IgG4)-related aortitis in patients who undergo aorta surgery and are diagnosed by pathology as having chronic aortic inflammation and to compare IgG4-related aortitis with other non-infectious aortitises in terms of clinical characteristics.	24447903
Communicable Diseases, Primary malignant neoplasm, Acute and chronic inflammation, Atherosclerosis	Altered Intercellular Communication	In total, 41 had chronic aortic inflammation without atherosclerosis, cancer or infection.	24447903
Acute and chronic inflammation, Aortitis	Altered Intercellular Communication	In patients with chronic aortic inflammation, 7% had IgG4-related aortitis.	24447903
Hypometabolism, Vascular insufficiency	Altered Intercellular Communication	This suggested a state of hypometabolism and vascular insufficiency along with an inflammatory condition during VaD.	24448401
Inflammation, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	Adiponectin could protect against chronic inflammation, atherosclerosis, and cardiovascular diseases.	24449263
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	A novel p53/microRNA-22/Cyr61 axis in synovial cells regulates inflammation in rheumatoid arthritis.	24449575
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	We previously showed that Cyr61 acts to promote fibroblast-like synoviocyte (FLS) proliferation and Th17 cell differentiation, suggesting that Cyr61 plays an important role in mediating the joint inflammation and damage in rheumatoid arthritis (RA).	24449575
Arthritis	Altered Intercellular Communication	Global and locus-specific 5hmC levels and gene expression changes were monitored in normal chondrocytes stimulated with inflammatory cytokines to identify the effect of joint inflammation.	24449578
Hashimoto Disease, Inflammation	Altered Intercellular Communication	Hashimoto thyroiditis is the most common type of inflammation of the thyroid gland.	24449727
Inflammation, Acute appendicitis NOS (disorder)	Altered Intercellular Communication	Histological analysis showed acute inflammation consistent with acute appendicitis caused by T. saginata.	24450232
Inflammation, Hyperkeratosis	Altered Intercellular Communication	In the patients with OLP, the highest correlation was found between the level of hyperkeratosis and WCQ test (b = 0.53; P < 0.000), inflammation and results of BDI test (b = 0.33; P < 0.002), and results of dynia test and STAI test (b = 0.31; P < 0.004).	24450470
Coronary Aneurysm, vascular inflammations, Clinical Events Domain	Altered Intercellular Communication	Oxidative stress (OS) is related to vascular inflammation possibly, contributing to the development of coronary ectasia (CE).	24451144
Primary malignant neoplasm, Cardiovascular Diseases, Inflammatory disorder, Diabetes Mellitus	Altered Intercellular Communication	Shift workers are affected by diet- and inflammation-related diseases, including cardiovascular disease, diabetes, and cancer.	24451608
Inflammation, Dental Plaque	Altered Intercellular Communication	The cumulative plaque score was 19.7%; 83.8% of patients showed normal gingiva, 10.1% displayed mild inflammation, and 6.1% showed moderate inflammation.	24451866
Neoplasms	Altered Intercellular Communication	The inflammation-based Glasgow prognostic score (GPS) has been demonstrated to be prognostic for various tumors.	24452408
Inflammation, Pruritus	Altered Intercellular Communication	Biofilm formation by AD-associated staphylococci almost certainly plays a major role in the occlusion of sweat ducts and leads to inflammation and pruritus.	24452476
CDISC Integrated Basic Data Structure Dataset, Gastrointestinal inflammation	Altered Intercellular Communication	Metallothioneins have been linked to IBDs, but their role in intestinal inflammation is inconclusive.	24452846
Inflammation, Colitis	Altered Intercellular Communication	Biopsies of patients with active colitis showed infiltration of MT-positive cells in a pattern that correlated with the grade of inflammation.	24452846
Inflammation, Weight decreased, Colitis	Altered Intercellular Communication	MT knockout mice displayed less severe acute dextran sulphate sodium (DSS)-induced colitis compared to congenic wild-type mice based on survival, weight loss, colon length, histological inflammation and leukocyte infiltration.	24452846
Inflammatory Bowel Diseases, Inflammation, Colitis	Altered Intercellular Communication	Since antibody blockade of extracellular MT can reduce colitis in mice, MT may act as a danger signal and may represent a novel target for reducing leukocyte infiltration and inflammation in IBD patients.	24452846
Inflammation, Atherosclerosis, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Inflammation plays a key role in the pathogenesis of atherosclerosis that is an underlying cause of coronary heart disease (CHD).	24453409
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Since the 1990s, some studies have shown an association between H. pylori infection and CHD, which may be mediated by inflammation.	24453409
Hypernatremia, Inflammation, Fibrosis Assessment, Ischemia	Altered Intercellular Communication	Among the potential stimuli for NP in clinically stable patients are persistent occult fluid overload, wall stress, inflammation, fibrosis, and ischemia.	24453873
Inflammation	Altered Intercellular Communication	An extensive body of evidence indicates that oxidative stress and inflammation play a central role in the degenerative changes of systemic tissues in aging.	24454842
Inflammation	Altered Intercellular Communication	Taken together these data suggest a progressive age associated increase in oxidative damage, inflammation and reduced [NAD(H)] in the brain which may be exacerbated by alcohol intake.	24454842
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	Chronic inflammation is considered as one of the contributing mechanisms of lower urinary tract symptoms (LUTS).	24454896
Inflammation, Urinary Bladder Diseases, Lower Urinary Tract Symptoms	Altered Intercellular Communication	Serum CRP levels are associated with storage LUTS and sensory bladder disorders, suggesting chronic inflammation might play a role in the patients with storage predominant LUTS.	24454896
Sleeplessness, Bipolar Disorder	Altered Intercellular Communication	The etiology of depressive symptoms associated with the transition to menopause is still unknown; hormonal changes, serotonergic system or insomnia, could be a trigger to depressive symptomatology.	24456541
Dysplasia, Carcinoma, Transitional Cell, Chronic inflammation	Altered Intercellular Communication	Pathology from the subsequent surgery demonstrated urothelial carcinoma in the retained ureteral segment in 8 patients, dysplasia or atypia in 3 patients, and 1 patient with chronic inflammation.	24456786
Inflammation, Prediabetes syndrome, Diabetes Mellitus	Altered Intercellular Communication	Vitamin-D supplementation in vitamin-D insufficient/deficient prediabetes individuals is associated with significantly lower progression to diabetes (6/55 vs. 13/49; p=0.04) and higher reversal to normoglycemia (23/55 vs. 10/49; p=0.02), associated with decreased insulin resistance and systemic inflammation (TNFa and IL6).	24456991
Kidney Failure, Chronic, Inflammation, Malnutrition	Altered Intercellular Communication	Inflammation and malnutrition are important features in patients with ESRD; however, data on changes in these parameters over time are scarce.	24458074
Inflammation	Altered Intercellular Communication	Although evidence supports a role for inflammation in interstitial cystitis/bladder pain syndrome (IC/BPS), the mechanism remains unknown.	24458144
Inflammation	Altered Intercellular Communication	Bladder biopsies were obtained from 53 IC/BPS patients and 27 controls, and hematoxylin and eosin staining, immunostaining and Western blotting were performed to detect inflammation, TRPV1-immunoreactive and PGP9.5-immunoreactive nerve fibers, and NGF, respectively.	24458144
Inflammation	Altered Intercellular Communication	Our study revealed increased severity of inflammation correlated with a higher expression of TRPV1-immunoreactive nerve fibers and NGF in IC/BPS and correlated with clinical symptoms.	24458144
Inflammation, Venous Invasion	Altered Intercellular Communication	TSP was associated with CSS in patients with stage I-III disease [hazard ratio (HR) 1.84, 95% confidence interval (CI) 1.17-2.92, P = 0.009], independent of age, systemic inflammation, N stage, venous invasion and Klintrup-Makinen score.	24458470
Inflammation	Altered Intercellular Communication	We hypothesized that the neutrophil/lymphocyte ratio (NLR), thought to be an indirect manifestation of tumor-promoting inflammation, may be associated with response to abiraterone.	24458472
Inflammation	Altered Intercellular Communication	Our data may help understand the role of systemic inflammation in mCRPC and warrant further research.	24458472
Hereditary Diseases, Vascular Diseases, Emotional problems	Altered Intercellular Communication	It has been reported in association with vascular problems, inflammatory conditions, inherited diseases, tractional problems, intraocular surgery and medications.	24459457
Inflammation, Hypertension, CTCAE, Units Of Measure - Siemens	Altered Intercellular Communication	We conclude that MHO is associated with a low inflammation state, and family history of hypertension may play a role in the MHO phenotype.	24460218
Inflammation, Obesity	Altered Intercellular Communication	A negative association between a marker of bone formation and a marker of gingival inflammation was observed as early as childhood among Caucasian children with a family history of obesity.	24460774
Inflammation, Hypermetabolism, Cachexia	Altered Intercellular Communication	Cancer cachexia (CC) is a syndrome characterized by wasting of lean body mass and fat, often driven by decreased food intake, hypermetabolism, and inflammation resulting in decreased lifespan and quality of life.	24462323
Pain Distress Question, Fracture, Complex Regional Pain Syndromes	Altered Intercellular Communication	In the rat fracture model of CRPS, exaggerated sensory and sympathetic neural signaling stimulate keratinocyte and mast cell proliferation, causing the local production of high levels of inflammatory cytokines leading to pain behavior.	24462502
Inflammation, Electrocardiogram: left ventricle hypertrophy (finding), Hypertrophy, Congestive heart failure	Altered Intercellular Communication	Congestive heart failure is associated with cardiomyocyte hypertrophy, inflammation, and apoptosis, but the role of PKR in left ventricular hypertrophy and the development of congestive heart failure has not been examined.	24463368
Hypernatremia, Myocarditis, Congestive heart failure	Altered Intercellular Communication	PKR is a maladaptive factor upregulated in hemodynamic overload that contributes to myocardial inflammation, cardiomyocyte apoptosis, and the development of congestive heart failure.	24463368
Inflammation, Chronic disease	Altered Intercellular Communication	Chronic inflammation has been implicated in the etiology of various chronic diseases.	24463788
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Supra-physiological DPDZ nNOS expression significantly reduced myocardial fibrosis, inflammation and apoptosis.	24463882
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Metabolic changes and inflammation could promote or aggravate atrial fibrillation.	24463922
Inflammation	Altered Intercellular Communication	Chronic inflammation and sustained stress may be involved in the progression of nonculprit lesions in patients with STEMI.	24463926
Inflammation, Hypertension, CTCAE, Vascular System Injuries	Altered Intercellular Communication	Erythropoietin-induced hypertension and vascular injury in mice overexpressing human endothelin-1: exercise attenuated hypertension, oxidative stress, inflammation and immune response.	24463938
Tissue damage, Inflammation	Altered Intercellular Communication	Various cytokines activated by the inhalation of coal dust may mediate inflammation and lead to tissue damage.	24464026
Thyroid carcinoma, Chronic inflammation	Altered Intercellular Communication	The etiopathogenesis of thyroid cancer has not been clearly elucidated although the role of chronical inflammation and the imbalance between pro- and anti-inflammatory cytokines may play a role in the etiology.	24464184
Inflammation, Non-alcoholic Fatty Liver Disease, Fatty degeneration	Altered Intercellular Communication	OxNASH correlated with NAS and with the individual histologic features of NAFLD, namely, steatosis, inflammation, and ballooning (P < 0.05), with the strongest association being with inflammation [rho (r) 0.40, 95 % confidence interval 0.23, 0.57, P < 0.001].	24464211
Clostridium difficile, Gastrointestinal inflammation	Altered Intercellular Communication	Markers of intestinal inflammation have been proposed for inclusion in Clostridium difficile diagnostic algorithms.	24464697
Gastrointestinal inflammation, Clostridium difficile enteritis	Altered Intercellular Communication	Faecal calprotectin (f-Cp), a sensitive marker of intestinal inflammation, was evaluated for utility in C. difficile diagnosis in the hospital setting.	24464697
Airway structure, Inflammation	Altered Intercellular Communication	Non-invasive assessment of upper and lower airway infection and inflammation in CF patients.	24464968
Inflammation, Aortic Stiffness	Altered Intercellular Communication	Acute inflammation reduces flow-mediated vasodilatation and increases arterial stiffness in young healthy individuals.	24465022
Inflammation	Altered Intercellular Communication	Our results suggest that acute inflammation induced by influenza vaccination did not affect endothelial function in older adults.	24465022
Inflammation, Organ Dysfunction Scores, Bacterial Infections	Altered Intercellular Communication	During bacterial infections, activated polymorphonuclear leukocytes (PMNs) cause inflammation and organ dysfunction in severely ill patients.	24465168
Microcirculatory Bed, Inflammation Mediators, Endothelial dysfunction, Cerebral dysfunction	Altered Intercellular Communication	The association with immunological biomarkers, metabolic cerebral dysfunction and microvascular damage suggests a possible endothelial dysfunction of the cerebral microcirculation or a potential inflammation-mediated shift of the neurovascular coupling.	24465419
Spinal stenosis of lumbar region, Inflammation, Fibrosis Assessment, Hypertrophy	Altered Intercellular Communication	Chronic inflammation and subsequent fibrosis induced by mechanical stress play an important role in ligamentum flavum (LF) hypertrophy and degeneration in patients with lumbar spinal canal stenosis (LSCS).	24465594
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Platelet turnover in stable coronary artery disease - influence of thrombopoietin and low-grade inflammation.	24465602
Inflammation, IL13 gene, Squamous cell carcinoma of the head and neck	Altered Intercellular Communication	By focusing on inflammation, the present study was designed to compare the immune response induced by allergic rhinitis (AR) and head and neck squamous cell carcinoma (HNSCC).	24466243
Meningioma, Inflammation	Altered Intercellular Communication	Meningiomas with prominent inflammation are traditionally classified as "lymphoplasmacyte-rich meningioma" (LPM).	24467316
Meningioma	Altered Intercellular Communication	Additionally, plasma cells represented only a minor component in most examples, whereas macrophages predominated, suggesting that "inflammation-rich meningioma" may be a more accurate term.	24467316
Communicable Diseases, Inflammation	Altered Intercellular Communication	In this prospective study, we investigated whether HD catheters induce inflammation independent of infection.	24467342
Communicable Diseases, Inflammation	Altered Intercellular Communication	Hemodialysis patients with a catheter have a heightened state of inflammation independent of infection, and thus our study supports the avoidance of catheters and a timely conversion to AVFs with catheter removal.	24467342
Inflammation	Altered Intercellular Communication	Surgical removal of the tissue altered by inflammation leads to the development of defects of various sizes, often circular from the glans penis to the scrotum.	24467680
Inflammation, Ulceration, CTCAE, Necrosis	Altered Intercellular Communication	After the application developed severe inflammation with ulceration and necrosis around the penis.	24467680
Degenerative polyarthritis, Hypernatremia, Obesity, teratologic	Altered Intercellular Communication	Distinct risk factors for the development of osteoarthritis have been described: general, unmodifiable risk factors (age, sex, and genetic makeup), general, modifiable risk factors (obesity and hormonal factors) and local risk factors (prior joint anomalies and joint overload).	24467954
Inflammation, Fever, CTCAE, Coughing, Acute Coryza, Streptococcal Infections	Altered Intercellular Communication	A five-point score predicting the presence of A/C/G streptococci [FeverPAIN: Fever; Purulence; Attend rapidly (<= 3 days); severe Inflammation; and No cough or coryza] had moderate predictive value (bootstrapped estimates of area under receiver operating characteristic curve: 0.73 cohort 1, 0.71 cohort 2) and identified a substantial number of participants at low risk of streptococcal infection.	24467988
Hemorrhagic, Inflammation, Lymphoma	Altered Intercellular Communication	Colonoscopy demonstrated hemorrhagic mucosal erosion with partial ulceration, and the subsequent pathological findings at the inflammation site suggested malignant lymphoma histopathology in the colon.	24468017
Inflammation, Asthma, Thrombophilia	Altered Intercellular Communication	Evidence suggests that statins may decrease inflammation, airway hyperreactivity, and hypercoagulability while improving revascularization mediated by cholesterol-independent pathways.	24468035
Inflammation, diabetic	Altered Intercellular Communication	While inflammation has been proposed to contribute to the adverse cardiovascular outcome in diabetic patients, the specific pathways involved have not been elucidated.	24468151
Inflammation, Breast Carcinoma, Fatigue	Altered Intercellular Communication	Yoga's impact on inflammation, mood, and fatigue in breast cancer survivors: a randomized controlled trial.	24470004
Inflammation, Fatigue	Altered Intercellular Communication	To evaluate yoga's impact on inflammation, mood, and fatigue.	24470004
Inflammation	Altered Intercellular Communication	Chronic inflammation may fuel declines in physical function leading to frailty and disability.	24470004
Inflammation, Fatigue	Altered Intercellular Communication	If yoga dampens or limits both fatigue and inflammation, then regular practice could have substantial health benefits.	24470004
Aggressive course, Inflammation	Altered Intercellular Communication	Cytologic atypia limited to areas of significant acute inflammation may occur in CC and should, in the absence of aggressive stromal invasion, not preclude a diagnosis of CC.	24470056
Inflammation	Altered Intercellular Communication	Mitochondrial components, including mitochondrial DNA (mtDNA), when released extracellularly, can act as "damage-associated molecular pattern" (DAMP) agents and cause inflammation.	24470107
Inflammation	Altered Intercellular Communication	Our findings therefore show that circulating mtDNA increases with age, and can significantly contribute to the maintenance of the low-grade, chronic inflammation observed in elderly people.	24470107
Gout	Altered Intercellular Communication	Myeloid-related proteins 8 and 14 contribute to monosodium urate monohydrate crystal-induced inflammation in gout.	24470119
Inflammation, Gout	Altered Intercellular Communication	These endogenous TLR-4 ligands released by activated phagocytes contribute to the maintenance of inflammation in gout.	24470119
Inflammation, Biliary calculi, Cancer of Digestive System	Altered Intercellular Communication	Gallstones and cholecystectomy may be related to digestive system cancer through inflammation, altered bile flux, and changes in metabolic hormone levels.	24470530
Inflammation, Biliary calculi, Cancer of Digestive System	Altered Intercellular Communication	Gallstones and cholecystectomy may be related to digestive system cancer through inflammation, altered bile flux, and changes in metabolic hormone levels.	24470530
Inflammation, Autoimmune thyroid disease	Altered Intercellular Communication	The association between selenium and inflammation and the relevance of selenoproteins in follicular thyroid cell physiology have pointed to a putative role of selenoproteins in the pathogenesis of autoimmune thyroid diseases.	24471570
Arthralgia, Inflammation, CDISC SEND Laboratory Animal Species Terminology	Altered Intercellular Communication	No major clinicopathological differences could be identified between the genospecies, but neural inflammation and arthralgia were seen more often in lesions caused by invasive ospC strains.	24471698
Myocardial fibrosis, Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	Association of inflammation, myocardial fibrosis and cardiac remodelling in patients with mild aortic stenosis as assessed by biomarkers and echocardiography.	24471798
Inflammation, Fibrosis Assessment, Fluid overload	Altered Intercellular Communication	Myocardial fibrosis in mild AS is independently associated with three factors: LV volume overload, aortic valve pressure overload and inflammation.	24471798
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Therefore, the impact of anti-AT1R and anti-ETAR Abs on initiation of inflammation and fibrosis was analyzed.	24472528
Pharyngeal fistula, Inflammation, Esophageal	Altered Intercellular Communication	In all 12 cases, the oesophageal stoma remained stable, without any complications such as pharyngeal fistula or inflammation.	24472660
Inflammation, Endometriosis	Altered Intercellular Communication	A pathological assessment showed peritoneal tissue with focal dark pigment associated with mild chronic inflammation and deposition of tattoo pigment; there was no evidence of endometriosis in the specimens.	24473152
Inflammation, physiopathological	Altered Intercellular Communication	Adipose dysfunction resulting from chronic inflammation and impaired adipogenesis has increasingly been recognized as a major contributor to obesity-mediated insulin resistance, but the molecular mechanisms that maintain healthy adipocytes and limit adipose inflammation remain unclear.	24473437
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	These data suggest that the SK1-S1P axis could be an attractive target for the development of treatments to ameliorate adipose inflammation and insulin resistance associated with obesity and type 2 diabetes.	24473437
Angle Closure Glaucoma	Altered Intercellular Communication	Inflammation-related cytokines of aqueous humor in acute primary angle-closure eyes.	24474267
Senile cataract, Angle Closure Glaucoma, Humor	Altered Intercellular Communication	To measure levels of various inflammation-related cytokines in the aqueous humor of patients with acute primary angle-closure (APAC) and senile cataract.	24474267
Inflammation, Dissection of aorta	Altered Intercellular Communication	Acute aortic dissection (AAD) causes transient inflammation with occasional pleural fluid (PF) accumulation.	24474442
Inflammation	Altered Intercellular Communication	Peptides genetically selected for NF-kB activation cooperate with oncogene Ras and model carcinogenic role of inflammation.	24474797
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Chronic inflammation is associated with increased cancer risk.	24474797
Inflammation, Carcinogenesis	Altered Intercellular Communication	This system provides an in vitro model of NF-kB-driven carcinogenesis and suggests that the known carcinogenic effects of inflammation may be at least partially due to NF-kB-mediated abrogation of oncogene-induced senescence.	24474797
Sepsis, Inflammation	Altered Intercellular Communication	Because interferon-gamma (IFN-g) plays an important role in inflammation, this work assessed IFN-g single nucleotide polymorphism (SNPs) that may be associated with sepsis.	24475220
Conjunctivitis	Altered Intercellular Communication	To correlate subclinical conjunctival inflammation and trabeculectomy results.	24475869
Inflammation, Neoplasms	Altered Intercellular Communication	Chronic inflammation plays a role in the mechanism that promotes tumor initiation.	24475998
Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	This study aimed to investigate the association between recurrence outcome and chronic inflammation-related co-morbidities in early-stage resected NSCLC.	24475998
Communicable Diseases, Chronic infectious disease	Altered Intercellular Communication	Further research is required to determine whether a TB infection resembles other chronic infections and inflammatory conditions in having a potential to facilitate oncogenesis.	24476016
Inflammation, Arthrodermataceae	Altered Intercellular Communication	The initial dermatologic examination led to the clinical diagnosis of inflammation of the scalp, while mycological analysis revealed an uncommon dermatophyte agent, Microsporum gypseum, in the culture.	24476613
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	Waist-to-height ratio, inflammation and CVD risk in obese children.	24476930
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Endothelial dysfunction	Altered Intercellular Communication	To evaluate the association between waist-to-height ratio (WHtR) and specific biomarkers of inflammation, CVD risk and endothelial dysfunction in prepubertal obese children.	24476930
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Obesity	Altered Intercellular Communication	Our results lead to the hypothesis that changes in biomarker levels of insulin resistance, inflammation and CVD risk before puberty might induce metabolic consequences of obesity in obese children before reaching adulthood.	24476930
Inflammation, Muscle (organ)	Altered Intercellular Communication	Physical inactivity, inadequate dietary protein, and low-grade systemic inflammation contribute to age-related muscle loss, impaired function, and disability.	24477043
Presenile dementia, Inflammation, Thrombophilia	Altered Intercellular Communication	We further focused on the role of dementia and cardiovascular risk factors as well as inflammation (C-reactive protein, fibrinogen) and hypercoagulability (fibrin d-dimers, thrombin generation) in these associations.	24477111
Inflammation, Critical Illness	Altered Intercellular Communication	The critically ill have increased REE according to inflammation defined by CRP.	24477456
Inflammation, Renal Cell Carcinoma Pathway	Altered Intercellular Communication	Systemic inflammation has been suggested to impact on the prognosis of metastatic renal cell carcinoma (mRCC).	24477648
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Atrial fibrillation is associated with inflammation and oxidative stress.	24477817
Inflammation, Atrial Fibrillation by ECG Finding, osteoclast activating factor	Altered Intercellular Communication	Carvedilol and N-acetyl cysteine (NAC) combination decreases inflammation, oxidative stress, and postoperative atrial fibrillation (POAF) rates more than metoprolol or carvedilol.	24477817
Inflammation	Altered Intercellular Communication	Carvedilol plus NAC reduced oxidative stress and inflammation compared with metoprolol and decreased oxidative stress compared with carvedilol.	24477817
Inflammation, Corneal Endothelial Cell Loss	Altered Intercellular Communication	The association of higher sVCAM-1 levels with decreased survival suggests that targeted therapies to reduce endothelial damage and inflammation may also be beneficial.	24478166
Intraocular inflammation	Altered Intercellular Communication	Both groups had the highest values of intraocular inflammation at the 1-week postoperative visit, followed by a decline to barely traceable levels at 1 month.	24479722
Interstitial inflammation, Idiopathic Interstitial Pneumonias, Fibrosis Assessment, Nonspecific interstitial pneumonia, Pneumonia, Interstitial	Altered Intercellular Communication	Nonspecific interstitial pneumonia (NSIP) is a form of idiopathic interstitial pneumonia characterized histologically by varying degrees of interstitial inflammation and fibrosis that are temporally and morphologically homogeneous in comparison with usual interstitial pneumonia (UIP).	24480140
Inflammation, Mood Disorders, Depression, Bipolar	Altered Intercellular Communication	IFN-alpha-induced increases in glutamate in dACC and basal ganglia are consistent with MRS findings in bipolar depression and suggest that inflammatory cytokines may contribute to glutamate alterations in patients with mood disorders and increased inflammation.	24481242
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Markers of inflammation, oxidative stress, and endothelial dysfunction and the 20-year cumulative incidence of early age-related macular degeneration: the Beaver Dam Eye Study.	24481424
methyldopa, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	OBJECTIVE To examine the relationships of markers of inflammation, oxidative stress, and endothelial dysfunction to the 20-year cumulative incidence of early AMD.	24481424
Compression of optic nerve, Orbital Pseudotumor	Altered Intercellular Communication	After initial treatment with pulsed intravenous methylprednisolone, followed by rituximab and radiotherapy, there was a marked improvement in orbital inflammation and clinical and radiological improvement in the compressive optic neuropathy.	24481505
IgG4-Related Sclerosing Disease, Ocular adnexa structure	Altered Intercellular Communication	IgG4-related disease (IgG4-RD) is an inflammatory condition of unknown etiology that can cause tumefactive lesions in a number of tissues and organs, including the orbit and ocular adnexa.	24481505
Biliary Colic, Cholecystitis, Cholelithiasis	Altered Intercellular Communication	Diagnosis is made on the basis of symptoms of biliary colic in the absence of cholelithiasis and gallbladder inflammation.	24481806
Inflammation, Carotid Stenosis, Cerebrovascular accident	Altered Intercellular Communication	Plaque inflammation and unstable morphology are associated with early stroke recurrence in symptomatic carotid stenosis.	24481971
Inflammation, Dental Plaque, Cerebrovascular accident	Altered Intercellular Communication	We aimed to investigate the relationship between early stroke recurrence after initial symptoms and histological features of plaque inflammation and instability in resected carotid plaque.	24481971
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	On multivariable Cox regression, including OPS macrophage grade (>=3 or <3), age, and severity of stenosis (50%-69% or >=70%), plaque inflammation was the only variable independently predicting stroke recurrence (adjusted hazard ratio, 9; confidence interval, 1.1-70.6; P=0.04).	24481971
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Plaque inflammation and other vulnerability features were associated with highest risk of stroke recurrence and may represent therapeutic targets for future stroke prevention trials.	24481971
Waldenstrom Macroglobulinemia, Fibrosis Assessment	Altered Intercellular Communication	Endoscopic ultrasound biopsy found pancreatic tissue with lymphoplasmacytic inflammation and fibrosis.	24482076
Inflammation	Altered Intercellular Communication	Steroid-eluting spacers can improve local drug delivery immediately following endoscopic sinus surgery and reduce the recurrence of inflammation warranting systemic corticosteroids.	24482348
Inflammation, Smoking, Diabetes Mellitus, Obesity, Hypertension, CTCAE	Altered Intercellular Communication	Smoking, diabetes, hypertension, inflammation and obesity explained some but not all of the remaining association.	24482683
Inflammation, Lymphoplasmacytic Infiltrate, Neoplasms	Altered Intercellular Communication	Only lymphoplasmocytic infiltration differed significantly, with P+ tumors exhibiting more intense inflammation (P = .041).	24482787
Squamous cell carcinoma of tongue, Inflammation	Altered Intercellular Communication	Despite the limited number of cases, the results of this study suggest that painful OSCCs of the tongue may be associated with more intense inflammation.	24482787
Coronary Artery Disease	Altered Intercellular Communication	Immunoglobulin G4 (IgG4)-related immuno-inflammation may play a role in the development of coronary artery disease (CAD).	24482807
Inflammation, Mediastinitis	Altered Intercellular Communication	[A rapidly progressive case of mediastinitis in which the patient developed inflammation of the soft tissue surrounding the pulmonary artery].	24483022
Inflammation, Fever, CTCAE, Leukopenia, Thrombocytopenia	Altered Intercellular Communication	The fever persisted for 4 days and, because elevated hepatobiliary enzymes, leukocytopenia and thrombocytopenia were observed, along with chest CT findings of inflammation of the soft tissues surrounding the left pulmonary artery, the patient was admitted for further examination.	24483022
Cushing Syndrome	Altered Intercellular Communication	Hormonal tests suggested the presence of Cushing's syndrome due to ectopic ACTH production.	24483161
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Parenterally administered ascorbic acid modulates sepsis-induced inflammation and coagulation in experimental animal models.	24484547
Single organ dysfunction, Inflammation, Endothelium	Altered Intercellular Communication	Intravenous ascorbic acid infusion was safe and well tolerated in this study and may positively impact the extent of multiple organ failure and biomarkers of inflammation and endothelial injury.	24484547
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Chronic inflammation is a major risk factor for the development and metastatic progression of cancer.	24484937
Nasal Polyps	Altered Intercellular Communication	Decrease in the activity and specific activity concentration of the majority of examined lysosomal exoglycosidases (increasing in inflammations) in comparison to hypertrophic lower nasal conchae suggests electrolytes disorders and questions the inflammatory background of nasal polyps.	24484945
Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Because they regulate arterial inflammation and are closely related to atherosclerosis and plaque instability, these two mutated genes have become a research hotspot.	24485247
Presenile dementia, Inflammation, Impaired cognition, Endothelial dysfunction	Altered Intercellular Communication	Low-grade inflammation and endothelial dysfunction are related to cognitive decline and dementia, in a complex interplay with vascular factors and aging.	24485482
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	We investigated, in an older population, low-grade inflammation and endothelial dysfunction in relation to detailed assessment of cognitive functioning.	24485482
Inflammation, Endothelial dysfunction, Cardiovascular Diseases	Altered Intercellular Communication	Low-grade inflammation and endothelial dysfunction accounted for only 2.6% explained variance in cognitive functioning, on top of related vascular risk factors and cardiovascular disease.	24485482
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Bootstrapping analyses show that low-grade inflammation and endothelial dysfunction mediate the relation between vascular risk factors and cognitive functioning.	24485482
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	This study shows that low-grade inflammation and endothelial dysfunction contribute to reduced information processing speed and executive functioning in an older population.	24485482
Inflammation, Immediate hypersensitivity	Altered Intercellular Communication	MCS individuals displayed a distinct systemic immune mediator profile with increased levels of pro-inflammatory cytokines and interleukin-2 and inverse regulation of Th2 associated cytokines interleukin-4 and interleukin-13 suggestive of low-grade systemic inflammation, along with a deviating Th2-associated cytokine response not involving IgE-mediated mechanisms.	24485486
Granulomatous inflammation, Encephalopathy, CTCAE 5.0, Calcified (qualifier)	Altered Intercellular Communication	At autopsy, multicystic encephalopathy was confirmed with bilateral gliosis, granulomatous inflammation with multinucleated giant cells, and calcifications.	24485930
Inflammation	Altered Intercellular Communication	However, it was still unclear whether these genital mycoplasmas would contribute to the development of inflammation of the male urethra.	24486047
Upper Respiratory Infections	Altered Intercellular Communication	Impaired granulocyte PKA function in AERD may lead to dysregulated control of 5-lipoxygenase activity by PGE(2), whereas adherent platelets lead to increased production of LTs, which contributes to the features of persistent respiratory tract inflammation and LT overproduction.	24486071
Respiration Disorders	Altered Intercellular Communication	Aspirin-exacerbated respiratory disease (AERD) is an inflammatory condition of the respiratory tract and is characterized by overproduction of leukotrienes (LT) and large numbers of circulating granulocyte-platelet complexes.	24486071
Inflammation, Hypertensive (finding), Corneal Endothelial Cell Loss	Altered Intercellular Communication	The polymorphism rs836478 was associated with an increased expression in markers of inflammation and endothelial damage (MMP9 and IL-6) in pediatric subjects with a hypertensive genetic background.	24487980
Inflammation	Altered Intercellular Communication	Compared with type A gastric microstructure, types B and C gastric microstructure showed a significantly higher degree of inflammation (P < 0.001).	24488235
Gastritis	Altered Intercellular Communication	The sensitivity, specificity and accuracy of types B + C microstructure as a predictor of gastric inflammation were 85.4, 81.7 and 83.1 %, respectively.	24488235
Inflammation	Altered Intercellular Communication	Osteoprotegerin (OPG) may contribute to the link between systemic inflammation and increased cardiovascular risk.	24488413
Parotid Neoplasms, Inflammation	Altered Intercellular Communication	A retrospective evaluation was carried out for all patients with signs of inflammation in the parotid gland on the ground of a benign parotid tumor, as confirmed by permanent histology.	24488708
Inflammation, Facial paralysis, Malignant Neoplasms	Altered Intercellular Communication	Diverse clinical signs (inflammation signs, facial palsy), ultrasound and MRI findings (poorly defined lesion margins), and the presence of squamous metaplastic changes on cytology often raised the suspicion of parotid malignancy or abscess.	24488708
Kidney Diseases, Nephritis	Altered Intercellular Communication	Monocyte chemoattractant protein-1 (MCP-1), which is up regulated in kidney diseases, is considered a marker of kidney inflammation.	24489972
Salmonella enterica subsp. salamae, Inflammation, Septic Shock, Bacteremia	Altered Intercellular Communication	By multivariate analysis, the major predictors of complicated S. aureus-CLABSI were septic shock, catheter site inflammation, presence of peripherally inserted central catheter, anti-cancer chemotherapy within 10 days, and persistent bacteremia beyond 72 hours (P <= 0.02).	24491173
Inflammation, HIV-Associated Lipodystrophy Syndrome, Obesity	Altered Intercellular Communication	Inflammation, and specifically adipose tissue (AT) inflammation, is part of the pathophysiology of obesity and HIV-associated lipodystrophy.	24494803
Refractory anemias, Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	Rheumatoid synovial fibroblasts (RASFs) mediate joint inflammation and destruction in rheumatoid arthritis (RA).	24495480
palladium, Inflammation	Altered Intercellular Communication	In addition, inflammation has been proposed as one of the factors contributing to PD pathophysiology.	24495872
palladium, Inflammation	Altered Intercellular Communication	Although adipokines play important roles in inflammation, it seems that they are not implicated in the inflammatory response associated with PD.	24495872
Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	No other reproductive or hormonal factor was associated with survival after an NSCLC diagnosis.	24496005
Benign Paroxysmal Positional Vertigo	Altered Intercellular Communication	Data suggest that hormonal fluctuations (especially during menopause) may increase the tendency to develop BPPV.	24496089
Inflammation, Obesity	Altered Intercellular Communication	Childhood obesity has recently been linked to low-grade inflammation.	24497216
Refractory anemias, Inflammation	Altered Intercellular Communication	Composite measures used to assess RA are flawed, as they confound RA inflammation and patient distress, and more consideration should be given to disaggregated assessments.	24497433
Carcinogenesis, Primary malignant neoplasm	Altered Intercellular Communication	Smoking-related cancer of the respiratory tract was found to affect the expression of genes encoding xenobiotic biotransformation proteins, as well as proteins associated with crucial inflammation/immunity pathways and other processes that protect the airway from the chemicals in cigarette smoke or contribute to carcinogenesis.	24497500
Inflammation, Malignant neoplasm of endometrium	Altered Intercellular Communication	Inflammation plays an important role in endometrial cancer etiology.	24500149
Inflammation, Skeletal muscle structure, Dermatomyositis, Childhood Type	Altered Intercellular Communication	Juvenile dermatomyositis (JDM) is a multisystem disease characterized by non-purulent inflammation in the striated muscle and skin.	24500836
Inflammation, Hypertrophic Cardiomyopathy	Altered Intercellular Communication	Vitamin D deficiency has been associated with the development of myocardial hypertrophy and inflammation.	24500905
Inflammation, diabetic	Altered Intercellular Communication	In summary, xenogenic transplantation of human SVF did not induce systemic inflammation and successfully improved erectile function in diabetic mice through enhanced penile angiogenesis and neural regeneration.	24501171
Inflammation, Pterygium Of Conjunctiva And Cornea	Altered Intercellular Communication	Concomitant examination of inflammation and angiogenesis in the pathogenesis of primary moderate pterygium in a well-designed case-control study.	24502169
Inflammation	Altered Intercellular Communication	Chronic inflammation and angiogenesis are two major proposed mechanisms of the disease in the current literature.	24502169
Inflammation, Pterygium Of Conjunctiva And Cornea	Altered Intercellular Communication	This study indicates that both inflammation and angiogenesis play pivotal role, in parallel, in pathogenesis of pterygium.	24502169
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	To investigate whether an adverse body composition is associated with endothelial dysfunction (ED) and the extent to which any such association could be explained by low-grade inflammation (LGI) and/or insulin resistance (HOMA2-IR).	24503113
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Visualizing inflammation activity in rheumatoid arthritis with Tc-99 m anti-CD4-mAb fragment scintigraphy.	24503329
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The serum level of OPN is correlated with severity of inflammation in the OA patients.	24503399
ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	To study the association of free immunoglobulin light chain (FLC) with clinical manifestations and lung inflammation in smokers with normal lung function and chronic obstructive pulmonary disease (COPD) patients.	24503428
HD Term Type, Inflammation	Altered Intercellular Communication	These data suggest that the consumption of only one Brazil nut per day during 3 months was effective to reduce the inflammation, oxidative stress markers, and the atherogenic risk, thereby increasing the antioxidant defenses in HD patients.	24504745
Gastrointestinal inflammation	Altered Intercellular Communication	The relationship between intestinal inflammation and circulating components of the renin-angiotensin system (RAS) is poorly understood.	24505094
Compressed structure, Inflammatory abnormality of the eye, Serous retinal detachment, Dystonia, Dopa-Responsive, due to Sepiapterin Reductase Deficiency	Altered Intercellular Communication	To evaluate the effectiveness of silicone oil tamponade in patients with chronic serous retinal detachment (SRD) persisting for three months after the resolution of ocular inflammation.	24505198
Tuberculosis, Pulmonary, Inflammatory abnormality of the eye, Dystonia, Dopa-Responsive, due to Sepiapterin Reductase Deficiency	Altered Intercellular Communication	A total of 17 eyes of 17 patients diagnosed with chronic SRD persisting for three months after the resolution of ocular inflammation and with high risk of phthisis bulbi by secondary ocular hypotony and macular detachment by subretinal fibrous membrane formation were subjected to surgical intervention.	24505198
Eye pain, Inflammation	Altered Intercellular Communication	During the first cycle of chemotherapy (cyclophosphamide, doxorubicin, vincristine, and prednisolone), the patient complained of right ocular pain and inflammation.	24505208
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The aims of the present study are 1) to determine whether LVM is associated with mortality and various cardiovascular events and 2) to identify determinants of LVM including biomarkers of inflammation and fibrosis.	24505249
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	No relationship was found between LVM and markers of inflammation and fibrosis.	24505249
Inflammation, Cardiac dysfunction, Anemia	Altered Intercellular Communication	Low TSAT was a significant independent risk factor for adverse clinical outcome in incident dialysis patients with anemia, which may be partly attributed to cardiac dysfunction and inflammation.	24505281
Steatohepatitis, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Positive correlations were found between liver inflammation and baseline CD4 count, sVCAM and HGF; fibrosis stage and HGF; liver steatosis, BMI and leptin.	24506344
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	IL-6/Stat3-driven pulmonary inflammation, but not emphysema, is dependent on interleukin-17A in mice.	24506702
Pulmonary Emphysema	Altered Intercellular Communication	Pulmonary emphysema is linked to T cell-mediated autoimmune inflammation, although the pathogenic role of specific pro-inflammatory cytokines remains unclear.	24506702
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	We therefore evaluated a causal role for IL-17A in the IL-6-driven gp130(F/F) mouse model for spontaneous pulmonary inflammation and emphysema.	24506702
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	Importantly, genetic ablation of Il17a in gp130(F/F) : Il17a-/- mice prevented lung inflammation; however, emphysema still developed.	24506702
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Consistent with these findings, augmented IL17A expression was observed in emphysema patients presenting with inflammation compared with inflammation-free individuals.	24506702
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	Collectively, our data suggest that the integration of IL-17A into the IL-6/Stat3 signalling axis mediates lung inflammation, but not emphysema, and that discrete targeting of IL-17A may alleviate pulmonary inflammatory-related diseases.	24506702
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Inflammation was an important process in the development of hypertension.	24507232
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	WHtR is a sensitive index associated with chronic inflammation in obese hypertensive subjects.	24507240
Inflammation, Neoplasms, Gain of Chromosome 8q, Structure of lamina episcleralis, Ocular Melanoma with Extraocular Extension, Loss of Chromosome 3	Altered Intercellular Communication	Statistical analysis (log-rank test or Cox regression analysis) was performed to correlate MFS with tumor characteristics, extraocular extension, episcleral diameter of the extraocular extension, cell type, extracellular matrix patterns, inflammation, loss of chromosome 3, and gain of chromosome 8q.	24508790
Inflammation, Atherosclerosis, Kit Ligand, human, Motor Disorders, Endothelial dysfunction	Altered Intercellular Communication	The exact pathophysiology of slow coronary flow (SCF) phenomenon, characterized by delayed opacification of coronary arteries during coronary angiography, is still unknown, although endothelial dysfunction, inflammation, vasomotor disorders and atherosclerosis are shown.	24509324
Inflammation, Kit Ligand, human, Atherosclerosis	Altered Intercellular Communication	We conclude that SCF phenomenon appears to be associated with enhanced procoagulant state, which may support the role of inflammation and atherosclerosis in the pathogenesis of this phenomenon.	24509324
Traumatic injury	Altered Intercellular Communication	Trauma stress and neuro-inflammation caused by surgery/anaesthesia releases cytokines.	24509399
Inflammation, Pain Distress Question	Altered Intercellular Communication	Protease-activated receptors (PARs) are a unique class of receptors which are implicated in mediating inflammation, pain and other functions.	24509446
Inflammation	Altered Intercellular Communication	The addition of only one marker of inflammation led to an adequate level of significance (ASDAS-CRP, p = 0.0018; ASDAS-ESR, p = 0.003).	24509896
Inflammation, Peritonitis, Cellulitis, Hernia, Shock	Altered Intercellular Communication	We classified the degree of clinical and bowel morphological changes into 3 grades based on the incarceration time, intestinal morphology after damage, hernia sac integrity, degree of inflammation, and the presence/absence of bacterial growth, peritonitis signs, mechanical obstruction, cellulitis, and systemic shock.	24509901
Inflammation, NLRP3 gene, Amyloid nephropathy	Altered Intercellular Communication	Our data, though limited to only two patients, emphasize that therapeutic intervention with canakinumab, suppressing both inflammation and IL-1b-mediated manifestations, can contribute to improve kidney function in MWS with overt renal amyloidosis.	24510061
Inflammation, Observation Method - Coagulation, Osage language	Altered Intercellular Communication	Systemic inflammation and coagulation may be related to cardiovascular pathophysiology in patients with OSA.	24510497
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Fibrinogen is a major coagulation protein associated with inflammation, and long-term elevated plasma fibrinogen is associated with an increased risk of major cardiovascular diseases.	24510497
Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Targeting angiopoietin-2 to attenuate inflammation and collagen expression may provide a novel therapy for cardiovascular disease in CKD.	24511140
Inflammation, Neoplasms	Altered Intercellular Communication	PDGFs/PDGFRs play critical roles in angiogenesis and possibly in inflammation, and they contribute to the pathogenesis of RN, irrespective of the original tumor pathology and applied radiation modality.	24512807
Inflammation, Neoplasms	Altered Intercellular Communication	The tumors were consisted of darkly staining basaloid cells and shadow cells, which most cases associated with polynuclear giant cell reaction and chronic inflammation.	24513001
Inflammation, Neoplasms, Osteogenesis, Calcinosis, Pilomatrixoma	Altered Intercellular Communication	Pilomatrixoma is a benign neoplasm which is mainly consisted of basaloid cells and shadow cells, usually combined with inflammation, foreign body giant cells, calcification and ossification.If a child or young patient has a firm subcutaneous mass in the upper eyelid or eyebrow area, a pilomatrixoma should be suspected.	24513001
allergic inflammation, "Extra-osseous Ewings sarcoma", Disease	Altered Intercellular Communication	Our observations place iNKT cells at the center of allergic inflammation associated with EoE, which could have profound implications for our understanding, treatment and prevention of this and other human allergic diseases.	24513807
Inflammation	Altered Intercellular Communication	Poor self-rated health (SRH) and elevated inflammation and morbidity and mortality are robustly associated in middle- and older-aged adults.	24513874
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Prediction of relapse after discontinuation of biologic agents by ultrasonographic assessment in patients with rheumatoid arthritis in clinical remission: high predictive values of total gray-scale and power Doppler scores that represent residual synovial inflammation before discontinuation.	24515410
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	This prospective study aimed to determine whether the comprehensive ultrasonographic assessment of synovial inflammation predicts relapse after discontinuation of treatment with a biologic agent in patients with rheumatoid arthritis (RA) in clinical remission.	24515410
Refractory anemias, Inflammation	Altered Intercellular Communication	In RA patients in clinical remission receiving treatment with a biologic agent, residual synovial inflammation determined by comprehensive ultrasound assessment predicted relapse within a short term after discontinuation of the treatment.	24515410
Stomach Carcinoma	Altered Intercellular Communication	Value of preoperative inflammation-based prognostic scores in predicting overall survival and disease-free survival in patients with gastric cancer.	24515568
Stomach Carcinoma	Altered Intercellular Communication	This study was designed to identify which are the best preoperative inflammation-based prognostic scores in terms of overall survival (OS) and disease-free survival (DFS) in patients with gastric cancer.	24515568
Inflammation, Pain Distress Question, Muscle damage, Swelling, Actual blood loss	Altered Intercellular Communication	Compared with Groups A and B, both serum inflammation and muscle damage markers were lower in Group C. There were no significant differences between the groups in terms of HSS knee score, ROM, estimated blood loss, swelling ratio, VAS pain score and hospital stays.	24515866
Intraoperative Blood Salvage, Inflammation, Muscle damage	Altered Intercellular Communication	Using a tourniquet full time in minimally invasive TKA causes less intraoperative blood loss and more excessive inflammation and muscle damage.	24515866
Inflammation, Granulation finding	Altered Intercellular Communication	Antibiotics have been shown to decrease local inflammation and granulation tissue formation in the trachea.	24515969
Injury of liver, Hepatitis, Chronic	Altered Intercellular Communication	Recent studies suggest that ongoing chronic liver inflammation is responsible for the liver injury in HCV-infected patients.	24516541
Communicable Diseases	Altered Intercellular Communication	Compared with uninfected individuals, HCV infection and HCV/HIV-1 coinfection markedly altered expression of 59.5% and 50.0% of 84 inflammation-related genes tested, respectively.	24516541
Inflammation, Carcinogenesis	Altered Intercellular Communication	Cyclooxygenase-2 (COX-2) is a key enzyme in the conversion of arachidonic acid to prostanoids, and its activation is associated with carcinogenesis as well as inflammation.	24516579
Autoimmune Diseases, Inflammation, Cholestanes, Primary Biliary Cholangitis	Altered Intercellular Communication	Primary biliary cirrhosis (PBC) is a chronic cholestatic, autoimmune, liver disease produced by inflammation and destruction of the interlobular bile ducts.	24516954
Inflammation, Atrophic	Altered Intercellular Communication	Although the inflammation was reduced after treatment, atrophy of the ganglion cells continuted to progress.	24516982
Inflammation, Impaired	Altered Intercellular Communication	TNFa is suspected to play a role in inflammation and insulin resistance leading to higher risk of metabolic impairment.	24517151
Heterotopic Ossification, Malignant Childhood Neoplasm	Altered Intercellular Communication	Inactivating mutation of the GNAS gene is associated with several diseases, which commonly manifest heterotopic ossification and hormonal resistance; however, the development of malignant neoplasm has never been reported.	24517547
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Because her fever and inflammation persisted, therapeutic cholecystectomy was performed.	24517554
Inflammation, Sleep Apnea, Obstructive, HIV Infections	Altered Intercellular Communication	Association between systemic inflammation and obstructive sleep apnea in men with or at risk for HIV infection.	24518040
Human immunodeficiency virus (HIV) status, Inflammation, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	We sought to determine whether markers of systemic inflammation are associated with the presence of moderate/severe obstructive sleep apnea (OSA) and whether this association differs based on HIV and HIV treatment status.	24518040
Inflammation	Altered Intercellular Communication	Compared with HIV+/HAART men and HIV- men, markers of systemic inflammation were higher in HIV+/no HAART men.	24518040
Inflammation, Weight decreased	Altered Intercellular Communication	Iron status and inflammation were improved by weight reduction.	24518166
Inflammation, Head of pancreas, Stricture of bile duct	Altered Intercellular Communication	Both pancreatic head swelling and IgG4-related biliary inflammation affect lower bile duct stricture, which may be included in IgG4-related sclerosing cholangitis.	24518505
Inflammation, Dysplasia	Altered Intercellular Communication	MACC1 overexpression (H-score >100) was seen in 67% of conventional CAC but in 0% of dysplasia and 0% of inflammation or normal colon.	24518605
methionine, Dysplasia, Inflammation	Altered Intercellular Communication	MET expressions in inflammation, dysplasia, and conventional CAC were statistically similar.	24518605
Inflammation, Disease remission	Altered Intercellular Communication	T2, T1Gad SIRs and n-ADC of EOMs were compared in patients with active inflammation, those with inactive disease and 26 healthy controls, and correlated with clinical scores.	24519110
Acute inflammation	Altered Intercellular Communication	Dexamethasone intravitreal implant to control postoperative inflammation may take several days until it achieves high concentrations in the vitreous.	24519510
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Systemic inflammation among breast cancer survivors: the roles of goal disengagement capacities and health-related self-protection.	24519882
Inflammation, Breast Carcinoma	Altered Intercellular Communication	The study's findings suggest that goal disengagement capacities and health-related self-protection can work together in predicting systemic inflammation among breast cancer survivors.	24519882
Airway structure, Ulcerative Colitis	Altered Intercellular Communication	The A1AT level in the serum and the colon tissue obviously decreased in UC patients, indicating the pulmonary function impairment of UC patients might manifest as decreased A1AT levels correlated chronic airway inflammation, remodeling of airway, and obstructive changes.	24520781
Inflammation, Dental Occlusion, Traumatic	Altered Intercellular Communication	This indicates the need to continuously monitor risk factors, including inflammation and traumatic occlusion, during SPT.	24521550
Refractory anemias	Altered Intercellular Communication	This Treg subset with Th17 plasticity in peripheral blood retained suppressive functions and was associated with milder inflammatory conditions, suggesting that this Treg population works as a negative regulator in RA, but in RA synovial site it may be pathogenic.	24521740
Inflammation, Psoriasis, Inflammatory dermatosis	Altered Intercellular Communication	Psoriasis is a chronic inflammatory skin disease and various stress factors mediate inflammation.	24521827
Inflammation	Altered Intercellular Communication	HSP90 from keratinocytes and mast cells is a key regulator of psoriatic inflammation and HSP90 inhibitors may represent a novel therapeutic approach to the disease.	24521827
Inflammation, Hypoxia, Lung	Altered Intercellular Communication	Application of continuous positive airway pressure (CPAP) to the collapsed lung potentially reduces pulmonary damage, hypoxia, and consequent inflammation.	24523436
Inflammation	Altered Intercellular Communication	Tertiary lymphoid tissue (TLT) is an ectopic organized lymph node-like structure that typically forms at sites of chronic inflammation and is involved in adaptive immune responses.	24523438
Inflammation, Osteoporosis, Postmenopausal	Altered Intercellular Communication	Recent studies revealed that inflammation plays a critical role in bone remodeling and the pathogenesis of postmenopausal osteoporosis, a major health concern.	24524373
Inflammation	Altered Intercellular Communication	Neutrophil-lymphocyte ratio (NLR) is a cost-effective marker of inflammation that has been linked with several diseases.	24524373
Steatohepatitis, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	A serum AIM level of >= 1.2 mg/ml was independently associated with advanced hepatic fibrosis (F2 or F3) (odds ratio [OR], 5.612; 95% confidence interval [CI], 1.103-28.563; P = 0.038) based on a multivariate analysis, but there was no significant association between AIM and hepatic steatosis or inflammation.	24524410
Steatohepatitis, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Furthermore, a serum leptin level of >= 8.6 ng/ml was independently associated with the presence of hepatic steatosis (>= 5%) (OR, 6.195; 95% CI, 1.409-27.240; P = 0.016), but not hepatic fibrosis or inflammation.	24524410
Communicable Diseases, Inflammation	Altered Intercellular Communication	Leptin (LPT), a hormone secreted by adipocytes,plays a role in inflammation and infection.	24524473
Communicable Diseases, Inflammation	Altered Intercellular Communication	Leptin (LPT), a hormone secreted by adipocytes,plays a role in inflammation and infection.	24524473
Asthma, Eosinophilic inflammation	Altered Intercellular Communication	Concomitant systemic and bronchial eosinophilic inflammation contribute to poor asthma control.	24525441
Inflammation, Mycobacterium Infections	Altered Intercellular Communication	A biopsy of granulation tissue obtained from the right external auditory canal demonstrated chronic inflammation that was suggestive of mycobacterial infection.	24526478
vascular inflammations, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Role of endothelial cell-derived angptl2 in vascular inflammation leading to endothelial dysfunction and atherosclerosis progression.	24526691
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Efforts to develop effective therapeutic strategies have focused on vascular inflammation as a critical pathology driving atherosclerosis progression.	24526691
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Here, we ask whether angiopoietin-like protein 2 (Angptl2), a proinflammatory protein, contributes to vascular inflammation that promotes atherosclerosis progression.	24526691
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Angptl2 knockout in apolipoprotein E-deficient mice (ApoE(-/-)/Angptl2(-/-)) attenuated atherosclerosis progression by decreasing the number of macrophages infiltrating atheromatous plaques, reducing vascular inflammation.	24526691
vascular inflammations, Dental Plaque	Altered Intercellular Communication	Conversely, ApoE(-/-) mice crossed with transgenic mice expressing Angptl2 driven by the Tie2 promoter (ApoE(-/-)/Tie2-Angptl2 Tg), which drives Angptl2 expression in endothelial cells but not monocytes/macrophages, showed accelerated plaque formation and vascular inflammation because of increased numbers of infiltrated macrophages in atheromatous plaques.	24526691
vascular inflammations, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Endothelial cell-derived Angptl2 accelerates vascular inflammation by activating proinflammatory signaling in endothelial cells and increasing macrophage infiltration, leading to endothelial dysfunction and atherosclerosis progression.	24526691
Cataract, Inflammation	Altered Intercellular Communication	Are increased levels of systemic oxidative stress and inflammation associated with age-related cataract?	24527727
Cataract, Inflammation	Altered Intercellular Communication	Oxidative stress and inflammation may be involved in the etiology of age-related cataract.	24527727
Inflammation	Altered Intercellular Communication	These results may support a role of cell-mediated inflammation in bone metabolism.	24528145
Inflammation, Calcified (qualifier), Aortic Valve Stenosis, Atherosclerosis	Altered Intercellular Communication	The role of inflammation in fibrotic and calcific processes of atherosclerosis and aortic stenosis (AS) is similar.	24528173
Inflammation, Heart failure	Altered Intercellular Communication	Furthermore, a relationship between systemic inflammation and heart failure has been well demonstrated.	24528173
Inflammation	Altered Intercellular Communication	Recently, neutrophil/lymphocyte ratio (NLR) has been proposed as a predictive marker of systemic inflammation.	24528173
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Netrin-1 and its receptor UNC5B play important roles in angiogenesis, embryonic development, cancer and inflammation.	24528886
Inflammation	Altered Intercellular Communication	Chemerin and interleukin (IL)-8 are pro-inflammatory mediators whose role in joint inflammation and cartilage degradation has been demonstrated in in-vitro findings.	24529071
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	T-lymphocytes, including Th17-cells and T-cells expressing acetylcholine (ACh), are key components of systemic inflammation in chronic obstructive pulmonary disease (COPD).	24529390
ARCN1 gene, Inflammation	Altered Intercellular Communication	We concluded that ACh might promote the increased levels of Th17-cells in systemic inflammation of COPD.	24529390
Gliosis, Depressive disorder, Dopamine Measurement	Altered Intercellular Communication	These genes are involved in different aspects of the inflammatory and immune response, oxidative stress, cell cycle activation and/or DNA repair, apoptosis, cytoskeleton reorganization and/or astrogliosis, synaptic plasticity and/or neurotransmission, and depressive disorders and/or dopamine-, serotonin-, GABA-signaling.	24529500
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Resolution of inflammation is altered in Alzheimer's disease.	24530025
Inflammation, "Alzheimers Disease", Data types - Address, Failure (biologic function)	Altered Intercellular Communication	Failure may lead to chronic inflammation, which is known as part of the pathology in the brain of individuals with Alzheimer's disease (AD).	24530025
Inflammation	Altered Intercellular Communication	These data indicate that the alteration of Th1/Th2/Th17/Treg paradigm exists in T2DN patients, which may contribute to the enhanced immune activation and inflammation, and subsequent development and progression of T2DN.	24530745
Inflammation, AUTONOMIC NERVOUS SYSTEM DYSFUNCTION	Altered Intercellular Communication	Some of the inflammation markers and autonomic nervous system dysfunction were also independently correlated with carotid IMT increase.	24530790
Inflammation, Depression, CTCAE, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Depression symptoms are independently associated with an accelerated progression of carotid IMT in subjects with CHD risk factors, and inflammation may substantially modulate the association between depression and carotid IMT progression.	24530790
Inflammation, Chronic heart failure	Altered Intercellular Communication	Inflammation is associated with progression of chronic heart failure (HF).	24530944
Inflammation, Family history	Altered Intercellular Communication	Our findings may implicate a pathogenic role for inflammation and TNF related molecules in FH, and these findings suggest the possibility that novel treatment modalities beyond that of statins and lipid lowering drugs may be useful in FH subjects.	24530965
Inflammation, Communicable Diseases, Edema, Conjunctivitis, Dysuria, meatitis	Altered Intercellular Communication	We describe two cases showing that adenoviral infection should be reasonably hypothesized in men with dysuria and scant urethral discharge in addition to meatus inflammation and/or edema (meatitis) or conjunctivitis.	24531179
Inflammation	Altered Intercellular Communication	Scant urethral mucoid secretions, severe meatal inflammation of the male patient were revealed during physical examination.	24531179
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	The role of methotrexate in resolving ocular inflammation after specific therapy for presumed latent syphilitic uveitis and presumed tuberculosis-related uveitis.	24531737
Intraocular inflammation	Altered Intercellular Communication	No recurrence of intraocular inflammation was observed in 6 months to 18 months of follow-up period after cessation of MTX.	24531737
Intraocular inflammation, Macular Edema, Cystoid, Uveitis	Altered Intercellular Communication	Two eyes of two patients with presumed tuberculosis-related uveitis showed improved best-corrected visual acuity, suppression of intraocular inflammation, and resolution of cystoid macular edema after intravitreal injections of MTX.	24531737
Intraocular inflammation, Macular retinal edema, Uveitis	Altered Intercellular Communication	For the first time in the treatment of presumed latent syphilitic uveitis and presumed tuberculosis-related uveitis, we believe that MTX might have an adjunctive role to suppress intraocular inflammation, reduce uveitic macular edema, and prevent the recurrences of the diseases.	24531737
Inflammation, Glomerulitis (disorder)	Altered Intercellular Communication	Microcirculation inflammation, particularly glomerulitis, irrespective of C4d, is associated with a high risk of development of TxGN at 1 year.	24531821
Inflammation	Altered Intercellular Communication	All these conditions cause inflammation and oxidative stress.	24531854
Inflammation, PTEN gene, Corneal Endothelial Cell Loss	Altered Intercellular Communication	The results of this study indicate an increased inflammation, endothelial damage, and oxidative stress in PTE.	24531854
Sacroiliitis, Inflammation	Altered Intercellular Communication	Degree of inflammation was accessed by spondylopathy, sacroiliitis as well as acute phase reactant, erythrocyte sedimentation rate and C-reactive protein (CRP).	24532142
ARCN1 gene, Inflammation, Impaired cognition, Anxiety, CTCAE 3.0, Chronic Obstructive Airway Disease, Asthma	Altered Intercellular Communication	Depressiveness, symptoms of anxiety and cognitive dysfunctions in patients with asthma and chronic obstructive pulmonary disease (COPD): possible associations with inflammation markers: a pilot study.	24532256
Pneumonitis	Altered Intercellular Communication	Cathepsin G degradation of phospholipid transfer protein (PLTP) augments pulmonary inflammation.	24532668
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Since PLTP expression is increased in chronic obstructive pulmonary disease (COPD), this study aimed to determine how PLTP affects lung signaling and inflammation.	24532668
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Airway inflammation persists after smoking cessation in established chronic obstructive pulmonary disease (COPD), suggesting that other factors drive the airway inflammatory response.	24532969
Airway structure	Altered Intercellular Communication	This is associated with a reduction in neutrophilic airway inflammation in patients with high bacterial loads.	24532969
Inflammation	Altered Intercellular Communication	Conversely, age could contribute to the inflammation found in old individuals by increasing the percentage of cells producing pro-inflammatory cytokines.	24533103
Metabolic Syndrome X	Altered Intercellular Communication	Serum immunoglobulin M concentration is positively related to metabolic syndrome in an adult population: Tianjin Chronic Low-Grade Systemic Inflammation and Health (TCLSIH) Cohort Study.	24533139
Inflammation, Metabolic Syndrome X, Cardiovascular Diseases	Altered Intercellular Communication	Persistent low-grade systemic inflammation has been increasingly recognized as a common pathological process, and an important contributing factor to cardiovascular diseases and its risk factor, metabolic syndrome.	24533139
Polymyositis, Skeletal muscle structure, Inflammation, Myositis	Altered Intercellular Communication	Polymyositis (PM) is an inflammatory muscle disease characterized by chronic inflammation in skeletal muscle.	24533547
Inflammation, Pustulosis of Palms and Soles, Acne, Synovitis, Osteitis, Sapho, Hyperostosis	Altered Intercellular Communication	Severe inflammation associated with synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome was markedly ameliorated by single use of minocycline.	24533553
Inflammation, Synovitis	Altered Intercellular Communication	Ultrasonographic examination of the joints revealed synovitis and inflammation by B mode and power Doppler ultrasonography.	24533558
Inflammation	Altered Intercellular Communication	Peripheral inflammation acutely impairs human spatial memory via actions on medial temporal lobe glucose metabolism.	24534013
Neurodegenerative Disorders	Altered Intercellular Communication	Inflammation impairs cognitive performance and is implicated in the progression of neurodegenerative disorders.	24534013
Inflammation, BDI - Functional Impairment	Altered Intercellular Communication	These data demonstrate acute sensitivity of human MTL to mild peripheral inflammation, giving rise to associated functional impairment in the form of reduced spatial memory performance.	24534013
Neurodegenerative Disorders, Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Our findings suggest a mechanism for the observed epidemiologic link between inflammation and risk of age-related cognitive decline and progression of neurodegenerative disorders including Alzheimer's disease.	24534013
Inflammation, Endotoxemia	Altered Intercellular Communication	Defective autophagy increases mortality and lung inflammation after endotoxemia.	24535031
Gastroesophageal reflux disease, Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	We aimed to investigate differences between pH measured directly in the lung, and biomarkers of acute inflammation in patients with newly diagnosed IPF and in patients with newly diagnosed GERD.	24535066
Nausea, Fatigue, Inflammatory disease of mucous membrane, Anorexia	Altered Intercellular Communication	They mainly consisted of gastrointestinal and general symptoms, such as fatigue, anorexia, mucosal inflammation or nausea.	24535315
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Enthesopathies are frequently found in rheumatic inflammatory diseases, but can be observed also in absence of systemic inflammation.	24535409
Liver carcinoma	Altered Intercellular Communication	The inflammation-based scores to predict prognosis of patients with hepatocellular carcinoma after hepatectomy.	24535607
Malignant neoplasm of liver, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The association of inflammation scores with clinicopathological variables and overall survival (OS) was analyzed, and the concordance index (C-index) was calculated to compare the predictive ability of each inflammation scores and staging systems including Barcelona Clinic Liver Cancer (BCLC) and Cancer of the Liver Italian Program (CLIP) scores.	24535607
Inflammation, Neoplasms	Altered Intercellular Communication	All inflammation scores, except PNI, were associated with tumor size, major/microvascular invasion and clinical stages, and the GPS and mGPS had a higher C-index (0.608).	24535607
Inflammation, FAM126A gene	Altered Intercellular Communication	The prognostic ability of the GPS is superior to other inflammation scores for patients undergoing hepatectomy as initial treatment for HCC.	24535607
Inflammation, Stricture of artery	Altered Intercellular Communication	FDG uptake occurred in areas of significant arterial stenosis, irrespective of the degree of inflammation.	24536009
Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	Serum connective tissue growth factor levels were negatively associated with estimated glomerular filtration rate (r = -0.46, p<0.001) and positively associated with interstitial inflammation (r = 0.309, p = 0.002) and interstitial fibrosis (r = 0.287, p = 0.004).	24536044
Inflammation, Coronary microvascular dysfunction, Lung Diseases, Obstructive, Obesity	Altered Intercellular Communication	Systemic inflammation is related to coronary microvascular dysfunction in obese patients without obstructive coronary disease.	24548662
Inflammation, Obesity	Altered Intercellular Communication	Obesity, systemic inflammation and changes in the heart functions are associated with increased cardiovascular risk.	24548662
Inflammation, physiopathological	Altered Intercellular Communication	This microvascular dysfunction seems to be related to a chronic inflammation mediated by adipocytokines.	24548662
Inflammation, Asthma	Altered Intercellular Communication	The complex relationship between inflammation and lung function in severe asthma.	24549277
Airway structure, Inflammation, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	Airway inflammation is thought to contribute to asthma pathogenesis, but the direct relationship between inflammation and airway hyperresponsiveness (AHR) remains unclear.	24549277
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	This study investigates the role of inflammation in a steroid-insensitive, severe allergic airway disease model and in severe asthmatics stratified by inflammatory profile.	24549277
Tumor necrosis, Asthma, Pneumonitis	Altered Intercellular Communication	First, we used the T-helper (T(H))-17 cells adoptive transfer mouse model of asthma to induce pulmonary inflammation, which was lessened by tumor necrosis factor (TNF)-a neutralization or neutrophil depletion.	24549277
Inflammation	Altered Intercellular Communication	Overall, this work suggests that lung compliance may be linked with cellular inflammation in the airspace, whereas T-cell-driven AHR may be associated with tissue inflammation and other pulmonary factors.	24549277
Inflammation, FBN2 wt Allele	Altered Intercellular Communication	Inflammation is known to be a risk factor for CCA development, and we tested whether this might induce Wnt/b-catenin signaling.	24549785
Autoimmune Diseases, Arthritis	Altered Intercellular Communication	Our data clearly show that smoking can change gene expression in the joints, which can lead to the activation of signalling pathways that promote development of autoimmunity and chronic joint inflammation.	24550170
Inflammation, Albuminuria, Chronic Kidney Diseases, Diabetes Mellitus	Altered Intercellular Communication	Association of race/ethnicity, inflammation, and albuminuria in patients with diabetes and early chronic kidney disease.	24550221
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation plays a critical role in the pathogenesis of diabetes-related CKD.	24550221
Inflammation, Tissue Adhesions	Altered Intercellular Communication	Various foot fillet flaps may be used acutely as a free or an island pedicled flap, but dissection of the vascular pedicle may be difficult in a chronically inflamed wound because of inflammation and adhesions to surrounding tissue.	24550664
Inflammation, Edema	Altered Intercellular Communication	Significant differences were found when comparing the degree of inflammation with nuclear alterations (p=0.001) and the same results when comparing the degree of edema and nuclear changes (p<0.001).	24551281
Inflammation, Edema	Altered Intercellular Communication	In clinics the predisposition of female patients to greater degree of edema and inflammation should be accounted for.	24551281
Hiccough	Altered Intercellular Communication	It is hypothesized that having both GABA and phenylethylamine properties activates inhibitory neurotransmitters, most notably GABA, which may in turn block the hiccup stimulus.	24551889
Pericarditis, CTCAE, Disorder of pericardium, Myocarditis, Compressed structure	Altered Intercellular Communication	Effusive-constrictive pericarditis, an uncommon pericardial syndrome, is characterized by simultaneous pericardial inflammation and tamponade.	24552226
Inflammation, Prostate carcinoma	Altered Intercellular Communication	The EPICAP study will particularly focused on the role of circadian disruption, chronic inflammation, hormonal and metabolic factors in the occurrence of prostate cancer.	24552491
Inflammation, Prostate carcinoma	Altered Intercellular Communication	The EPICAP study will particularly focused on the role of circadian disruption, chronic inflammation, hormonal and metabolic factors in the occurrence of prostate cancer.	24552491
Breast Carcinoma	Altered Intercellular Communication	Consistent findings across case-control and cohort investigations, complemented by pooled analyses, indicated important roles for anthropometric and hormonal risk factors in the etiology of male breast cancer.	24552677
Tumor necrosis, Heat-Shock Response, Gastrointestinal inflammation	Altered Intercellular Communication	Targeted inhibition of heat shock protein 90 suppresses tumor necrosis factor-a and ameliorates murine intestinal inflammation.	24552830
Inflammation, Heat-Shock Response, Gastrointestinal inflammation	Altered Intercellular Communication	Given the critical role of the heat shock response in regulating inflammation, this study proposed to define the impact of selective inhibition of heat shock protein 90 (HSP90) on intestinal inflammation.	24552830
Inflammation	Altered Intercellular Communication	Peritoneal dialysis patients present chronic inflammation and Th1/Th2 imbalance, but the role of the Th17 response in peritoneal membrane damage has not been investigated.	24552849
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Studies in mice showed that repeated exposure to recombinant IL-17A caused peritoneal inflammation and fibrosis.	24552849
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	IL-17A neutralization diminished experimental peritoneal inflammation and fibrosis caused by chronic exposure to dialysis fluids in mice.	24552849
Inflammation, Arthropathy associated with infection, Communicable Diseases, Postoperative infection, Infection, Urinary tract infection	Altered Intercellular Communication	The types of postoperative infection were recorded and included lower or upper respiratory tract and lung infection, bone and joint infection, wound inflammation or infection, urinary tract infection, and other infections.	24553882
Inflammation	Altered Intercellular Communication	These data provide evidence that asymptomatic HSV-2 shedding contributes to chronic inflammation throughout the genital tract.	24554666
Inflammation	Altered Intercellular Communication	These findings suggest that widespread asymptomatic genital HSV-2 shedding is associated with a targeted host immune response and contributes to chronic inflammation throughout the genital tract.	24554666
Acute cholecystitis without calculus, Inflammation, Peritonitis	Altered Intercellular Communication	Ultrasonic versus standard electric dissection in laparoscopic cholecystectomy in patients with acute calculous cholecystitis, complicated by peritonitis: influence on the postoperative systemic inflammation and immune response.	24555909
Bacteremia, Inflammation, Biliary peritonitis, Ulcerative Colitis	Altered Intercellular Communication	Laparoscopic cholecystectomy after biliary peritonitis, conducted by ELC, increased the incidence of bacteremia and systemic inflammation compared with the UC group.	24555909
Sepsis, Inflammation	Altered Intercellular Communication	Early enhanced postoperative systemic inflammation may cause lower transient immunologic defense in the ELC group, leading to enhanced sepsis.	24555909
Chikungunya Fever	Altered Intercellular Communication	Inflammation of the external ear in acute chikungunya infection: Experience from the outbreak in Johor Bahru, Malaysia, 2008.	24556566
Inflammation, Feeling calm	Altered Intercellular Communication	Although cytological atypia of the melanocytes is not sufficient to ALM in situ, the melanocytic proliferation pattern, dermal inflammation, and correlation with clinical presentation would suffice in making the correct diagnosis of ALM in situ.	24556899
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	Chronic inflammation enhances NGF-b/TrkA system expression via EGFR/MEK/ERK pathway activation in Sjogren's syndrome.	24557415
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	Inflammation, especially the cytokine response of the IL-1 family, has been shown to influence susceptibility to gastric cancer.	24557417
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	Lysyl-tRNA synthetase (KRS) expression in gastric carcinoma and tumor-associated inflammation.	24558064
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	KRS-related inflammation can be identified in a subset of gastric cancer.	24558064
ARCN1 gene, Inflammation	Altered Intercellular Communication	Air pollution and biomarkers of systemic inflammation and tissue repair in COPD patients.	24558180
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The origin(s) of systemic inflammation in patients with chronic obstructive pulmonary disease (COPD) is unclear.	24558180
ARCN1 gene, Inflammation	Altered Intercellular Communication	These results show that exposure to ambient NO2 increases systemic inflammation in COPD patients, especially in former smokers.	24558180
Inflammation	Altered Intercellular Communication	Interleukin-17-producing CD4+ effector memory T (Th17) cells and CD4+CD25+Foxp3 regulatory T (Treg) cells both play critical roles in immune activation and inflammation.	24558316
ARCN1 gene, Airway structure, Communicable Diseases, Fibrosis Assessment, Chronic Obstructive Airway Disease	Altered Intercellular Communication	In human airways diseases, including cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD), host defense is compromised and airways inflammation and infection often result.	24558372
Pain Distress Question, Inflammation, Rheumatoid Arthritis, Depression, CTCAE, Inflammatory disorder, Fatigue	Altered Intercellular Communication	Poor sleep is prevalent in patients with systemic inflammatory disorders, including rheumatoid arthritis, and, in addition to fatigue, pain, depression and inflammation, is associated with an increased risk of co-morbidity and all-cause mortality.	24559487
Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Obesity, physiopathological	Altered Intercellular Communication	Inflammation, insulin resistance and vascular dysfunction characterize obesity and predict development of cardiovascular disease (CVD).	24559846
Inflammation	Altered Intercellular Communication	Progerin was found to be significantly increased in the media of the dilated wall in tricuspidy, also showing increased periaortic inflammation.	24560417
Orbital Pseudotumor	Altered Intercellular Communication	This study was designed to compare GPA with other causes of orbital inflammation and to identify the presenting clinical and imaging features most likely to predict GPA and its systemic spread.	24560566
Orbital Pseudotumor	Altered Intercellular Communication	A total of 247 patients who had undergone orbital biopsies for clinical presentations with orbital inflammation were identified from the Institute of Ophthalmology pathology database.	24560566
Inflammation, Thrombophilia	Altered Intercellular Communication	These findings not only support the hypothesis of an association between inflammation and hypercoagulability, but more importantly, highlight the role of neutrophils in this process.	24560897
Inflammation, Pancreatitis	Altered Intercellular Communication	Chronic pancreatitis is a gradual, long-term inflammation of the pancreas that results in alteration of its normal structure and function.	24560933
Inflammation, Pathology	Altered Intercellular Communication	An increase in plasma kynurenic acid (KYNA) concentration has been observed following surgery, inflammation, and cerebral pathologies.	24561546
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Imaging myocardium at risk and coronary inflammation in non-ST-segment elevation myocardial infarction: combined use of FDG PET and optical coherence tomography.	24561688
Inflammation	Altered Intercellular Communication	In this report (figure), we describe the potential utility of FDG PET in defining the myocardium at risk and to unravel coronary inflammation in one NSTEMI patient with normal level of C-reactive protein.	24561688
Pancreatitis	Altered Intercellular Communication	Abdominal computed tomography revealed pancreatic and peripancreatic inflammation.	24561842
Arthritis, Disease remission	Altered Intercellular Communication	Diminution of miR-146a expression was observed in particular in patients with active disease, and correlated with joint inflammation.	24562503
Inflammation	Altered Intercellular Communication	Repeated strenuous work in the heat may predispose firefighters to augmented immune responses and inflammation.	24563092
Venous Thrombosis	Altered Intercellular Communication	Oral hormonal contraceptives may increase the risk of vascular events, even in people without personal or family history of venous thrombosis.	24564051
Inflammation, Diabetic Angiopathies, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Monitoring of glycation, oxidative stress and inflammation in relation to the occurrence of vascular complications in patients with type 2 diabetes mellitus.	24564602
ARCN1 gene, Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	In COPD with emphysema, loss of lung tissue may counterbalance the expected increase in density due to inflammation.	24564813
Inflammation, Adenolymphoma	Altered Intercellular Communication	We previously reported a case of immunoglobulin (Ig)G4-related immune inflammation in Warthin tumor.	24565204
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Chronic inflammation plays a role in the development of colorectal cancer (CRC).	24565956
Gastrointestinal inflammation	Altered Intercellular Communication	Faecal calprotectin (FC) is a non-invasive marker of gastrointestinal inflammation.	24566170
Degenerative polyarthritis, Degenerative disorder	Altered Intercellular Communication	Osteoarthritis (OA) is a chronic degenerative joint disorder in which genetic, hormonal, mechanical and ageing factors affect its progression.	24566851
Inflammation, Data types - Address	Altered Intercellular Communication	The data identify a specific AGE (MG) as a modifiable risk factor for AD and MS, possibly acting via suppressed SIRT1 and other host defenses, to promote chronic oxidant stress and inflammation.	24567379
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histologically, the excised tissue demonstrated marked inflammation with fibrosis surrounded by mononuclear epithelial cells.	24568363
Inflammation, Lacrimal sac, Orbital Neoplasms	Altered Intercellular Communication	It is likely that IgG4-related inflammation occurs in a lacrimal sac diverticulum, which should be considered a differential diagnosis in inferior orbital tumors.	24568363
Stomach Carcinoma	Altered Intercellular Communication	Neutrophil count and the inflammation-based glasgow prognostic score predict survival in patients with advanced gastric cancer receiving first-line chemotherapy.	24568523
Malignant Neoplasms, septic	Altered Intercellular Communication	Malignancy, hormonal and septic workup were all unremarkable.	24569260
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Time course of inflammation resolution in patients with frequent exacerbations of chronic obstructive pulmonary disease.	24569299
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	When exacerbation of chronic obstructive pulmonary disease (AECOPD) occurs frequently, patients have high levels of airway and systemic inflammation and a poor quality of life.	24569299
Airway structure, Exacerbation	Altered Intercellular Communication	This study compared the nature and course of systemic and airway inflammation during AECOPD between patients who experienced frequent exacerbations and those with non-frequent exacerbations.	24569299
Refractory anemias, Inflammation	Altered Intercellular Communication	Women with anti-CCP-positive RA and anti-CCP-negative RA had different characteristics with regard to HLA shared epitope, cigarette smoking, and inflammation (cytokines).	24569640
Inflammatory Bowel Diseases, Inflammation, Primary malignant neoplasm, Specimen Type - Fistula	Altered Intercellular Communication	Our limited retrospective study demonstrates that rectal cancer in IBD patients can present as a circumferential wall thickening resembling inflammation and can occur in the absence of fistula or abscess.	24570133
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Low-dose continuous infusion of landiolol reduced the incidence of postoperative atrial fibrillation, and significantly suppressed inflammation.	24570490
Inflammation, Impaired cognition	Altered Intercellular Communication	Systemic inflammation has been implicated in the development of cognitive dysfunction following carotid endarterectomy (CEA).	24571940
Inflammation, Hypercholesterolemia, Family history, Atherosclerosis	Altered Intercellular Communication	A correlation has been clearly shown between inflammation markers and subclinical atherosclerosis markers in the early stages of atherogenesis in subjects with familial hypercholesterolemia (FH).	24572981
Inflammation, Family history, Atherosclerosis	Altered Intercellular Communication	The aim of this study was to investigate potential inflammation markers in the diagnosis of atherosclerosis in children with FH.	24572981
TNF protein, human, Inflammation	Altered Intercellular Communication	Inflammation and macrophage activation markers (hsCRP, myeloperoxidase, chitotriosidase, YKL-40, TNF-a, IL-6, IL-18, MMP-1 and MMP-9) and lipid parameters of all patients were measured.	24572981
Inflammation, Atherosclerosis	Altered Intercellular Communication	ChT and YKL-40 seem to be the more predictable markers of atherosclerosis even in early ages (<6 years old) than other classical inflammation markers such as hs-CRP, IL-6 and TNF-a.	24572981
Inflammation, Fever, CTCAE	Altered Intercellular Communication	However, it was safe and well tolerated and reduced fever duration, some markers of inflammation, left anterior descending coronary artery Z score, and intravenous immunoglobulin reaction rates.	24572997
Inflammation	Altered Intercellular Communication	US assessment of synovial pathologic features in joints with mild inflammation was less reproducible than that in joints with severe inflammation.	24574211
Inflammation	Altered Intercellular Communication	Assessment of synovial fluid accumulation was not reproducible (ICCs 0.20-0.42) and did not substantially influence the global assessment of synovial inflammation (b = 0.06).	24574211
Inflammation, Spondylarthritis	Altered Intercellular Communication	Spinal inflammation in the absence of sacroiliac joint inflammation on magnetic resonance imaging in patients with active nonradiographic axial spondyloarthritis.	24574227
Inflammation, Spondylarthritis	Altered Intercellular Communication	To evaluate the presence of spinal inflammation with and without sacroiliac (SI) joint inflammation on magnetic resonance imaging (MRI) in patients with active nonradiographic axial spondyloarthritis (SpA), and to compare the disease characteristics of these subgroups.	24574227
Inflammation	Altered Intercellular Communication	Positive evidence of inflammation on MRI was defined as a SPARCC score of >=2 for either the SI joints or the spine.	24574227
Inflammation	Altered Intercellular Communication	Assessment by experienced readers showed that spinal inflammation on MRI might be observed in half of patients with nonradiographic axial SpA without SI joint inflammation.	24574227
Inflammation, Squamous metaplasia	Altered Intercellular Communication	The most common morphological finding in the epithelium was squamous metaplasia with occasional intense inflammation visible in the underlying mucosa, including cicatrization.	24574420
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	ARFI correlated with fibrosis stage and hyaluronic acid but not with inflammation.	24574802
Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Fatty degeneration, Balloon Dilatation	Altered Intercellular Communication	Liver biopsy revealed mild steatosis, moderate inflammation, ballooning degeneration, and portal fibrosis with bridging fibrosis; on the basis of these findings, the diagnosis of nonalcoholic steatohepatitis was made.	24575585
Inflammation, Hypertension, CTCAE, Chronic Kidney Diseases	Altered Intercellular Communication	A positive association between inflammation and chronic kidney disease (CKD) has been reported but the impact of hypertension on this relation remains unclear.	24575880
Inflammation, Hypertensive (finding), Damage	Altered Intercellular Communication	Our data suggest that inflammation is strongly and independently associated with renal damage in hypertensive patients.	24575880
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Relative enhancement negatively correlated with the degree of lobular inflammation (r = -0.59, P < .0001), ballooning (r = -0.44, P < .0001), and fibrosis (r = -0.59, P <= .0001), but not with steatosis (r = -0.16, P = .15).	24576046
Inflammation, Nerve Degeneration	Altered Intercellular Communication	The increase in BDNF might reflect a compensatory mechanism against early neurodegeneration and seems to be related to inflammation.	24576746
Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	Debate remains regarding whether the systemic inflammatory response syndrome (SIRS) identifies patients with clinically important inflammation.	24576975
Pleurisy, Abnormality of the diaphragm	Altered Intercellular Communication	Endoscopic findings included diffuse parietal pleural inflammation in 26 patients (51%), parietal pleural studding in 19 patients (37.3%), a normal examination in three patients (5.9%), diffuse parietal pleural thickening in two patients (3.9%), and a diaphragmatic defect in one patient (2%).	24577099
Behavioral and psychological symptoms of dementia, Inflammation, "Alzheimers Disease	Altered Intercellular Communication	The impact of APOE status on relationship of biomarkers of vascular risk and systemic inflammation to neuropsychiatric symptoms in Alzheimer's disease.	24577461
Inflammation, Nail-Patella Syndrome, Data types - Address	Altered Intercellular Communication	Previous work has shown a relationship between serum biomarkers of vascular risk and inflammation and NPS in AD.	24577461
Inflammation, Data types - Address	Altered Intercellular Communication	Serum-based clinical biomarkers of vascular risk and biomarkers of inflammation related to AD were analyzed.	24577461
Stable chronic Graft vs Host Disease, Inflammation	Altered Intercellular Communication	Activation and migration of regulatory T cells (Treg) into tissue is critical in control of inflammation, but has not been examined extensively in chronic graft versus host disease (cGVHD).	24577531
Inflammation, Primary malignant neoplasm, Weight decreased	Altered Intercellular Communication	In male patients with cancer, low testosterone levels were associated with systemic inflammation, weight loss, increased symptom burden, and decreased survival.	24577665
Hepatitis	Altered Intercellular Communication	The result indicates that cellular immunology is involved in the pathogenesis of the liver inflammation process of FHB.	24579463
Inflammation	Altered Intercellular Communication	[Comparative study on the clinical characteristics of HBV infection patients with different pathologic inflammation grade].	24579472
Inflammation, Liver damage	Altered Intercellular Communication	The serum AST, TBil, ALB and PTA were different and can partly reflect the inflammation degree of liver damage in patients with HBV infection.	24579472
Inflammation	Altered Intercellular Communication	HBV DNA level and HBeAg status can not indicate the inflammation degree in HBV infection patients.	24579472
Inflammation, Cervix carcinoma, Condylomata Acuminata, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	Among 3197 cases, 58.6% cases with chronic inflammation, 26.1% cases with condyloma or CIN I, 14.1% cases with CIN II-III, and 1.2% cases with invasive cervical carcinoma.	24579473
Diabetic Nephropathy, Inflammation, Kidney Diseases, Chronic Kidney Diseases	Altered Intercellular Communication	Determination of oxidative stress and cellular inflammation in patients with diabetic nephropathy and non-diabetic nephropathy being administered hemodialysis treatment due to chronic renal failure.	24579657
ARCN1 gene, Inflammation	Altered Intercellular Communication	In COPD smokers a weak correlation between 2006/2007 sputum markers of neutrophilic inflammation and the 5 year change in FEV1/FVC was found.	24581181
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	The diabetes mellitus can affect various functions of the immune system of the individual, predisposing them to chronic inflammation, progressive degradation of tissues and decreased tissue repair.	24581189
Respiration Disorders, Bronchial Hyperreactivity	Altered Intercellular Communication	Asthma is a chronic respiratory disease characterized by hyper-responsiveness and bronchial inflammation.	24581194
Bronchitis	Altered Intercellular Communication	The bronchial inflammation in these patients can be monitored by measuring the fractional exhaled nitric oxide.	24581194
Inflammation, Neoplasms	Altered Intercellular Communication	Recent evidence indicates that tumor progression involves factors of systemic inflammation, such as platelets and lymphocytes.	24581872
Traditional Serrated Adenoma, Tubulovillous adenoma, Inflammation, Neoplasms, Tubular adenoma, Adenocarcinoma, Hyperplastic Polyp	Altered Intercellular Communication	Two hundred and fifty-eight biopsies revealed tubular adenomas (n = 91, one with intra-mucosal cancer), tubulovillous adenomas (n = 28), adenocarcinoma (n = 37), inflammation (n = 22), hyperplastic polyps (n = 54), serrated adenoma (n = 5), metastatic disease (n = 5), normal/benign mucosa or submucosal benign tumors (n = 13) or miscellaneous (n = 3).	24581969
Airway structure, Asthma	Altered Intercellular Communication	Airway inflammation is associated with asthma exacerbation risk, treatment response, and disease mechanisms.	24582314
Non-alcoholic Fatty Liver Disease, Inflammation, Obesity, Abdominal, Fatty degeneration	Altered Intercellular Communication	Nonalcoholic fatty liver disease (NAFLD), characterized by accumulation of hepatic triglycerides (steatosis), is associated with abdominal obesity, insulin resistance, and inflammation.	24582567
Inflammation	Altered Intercellular Communication	It was also significantly associated with severe intraplaque hemorrhage (P<.0001) and the prevalence of cap inflammation with macrophage (P=.03) and lymphocyte (P=.01) infiltration.	24582790
Diplopia, Inflammation, Eye Movements	Altered Intercellular Communication	Secondary outcome measures were changes in other parameters indicating the activity of TED, including soft tissue inflammation, diplopia, ocular motility restriction, and appearance.	24582992
Inflammatory abnormality of the eye	Altered Intercellular Communication	Although both groups experienced a significant reduction in periocular inflammation, the radiotherapy-treated group demonstrated a significantly greater improvement in ocular motility.	24582992
agep, Inflammation, Fever, CTCAE	Altered Intercellular Communication	Although rare, physicians should be aware that the administration of DAP can cause AGEP, which may complicate the clinical course of patients with a high fever and inflammation.	24583445
Gastrointestinal inflammation	Altered Intercellular Communication	Colonic expression of the peptide transporter PEPT1 is downregulated during intestinal inflammation and is not required for NOD2-dependent immune activation.	24583477
Inflammation	Altered Intercellular Communication	PEPT1 expression was consistently reduced under condition of acute or chronic experimental inflammation.	24583477
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	PEPT1 expression levels were also decreased in descending colon of patients with IBD during acute inflammation, but the rs2297322 single-nucleotide polymorphism was not associated with IBD susceptibility in the German cohort.	24583477
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	PEPT1 expression is reduced during intestinal inflammation and PEPT1 is neither required for MDP-induced immune response nor is the PEPT1 rs2297322 single-nucleotide polymorphism associated with IBD susceptibility in our German cohort.	24583477
Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	To differentially diagnose collagen disease, infection, malignancy, and inflammation of uncommon causes, we conducted brain and meningeal biopsies on the 15th hospital day.	24583589
Inflammation, Necrosis	Altered Intercellular Communication	Histopathological examination of the brain tissue showed mainly necrosis and inflammation.	24583589
Inflammation, Acute-On-Chronic Liver Failure, Bacterial Infections, CRNKL1 wt Allele, Liver Cirrhosis	Altered Intercellular Communication	According to the Acute-on-Chronic Liver Failure in Cirrhosis study, ACLF is now considered a new clinical entity because it is distinct from traditional decompensated cirrhosis, based not only on the presence of organ failure(s) and high mortality rate but also on younger age, alcoholic etiology of cirrhosis, higher prevalence of some precipitating events (bacterial infections, active alcoholism), and higher level of systemic inflammation.	24583872
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	Eosinophilic inflammation of chronic rhinosinusitis with nasal polyps is related to OX40 ligand expression.	24583911
Inflammation, Nasal Polyps	Altered Intercellular Communication	In conclusion, the thymic stromal lymphopoietin/OX40 ligand axis is up-regulated in nasal polyposis and is related to the intensity of eosinophilic inflammation.	24583911
Tuberculosis, Pulmonary	Altered Intercellular Communication	Despite increased pro-inflammation compared to the uninfected controls; there was no up-regulation of IFN-g or the T cell chemoattractant CCL5 in the lung of patients with pulmonary TB.	24584041
Inflammation, Recurrent sinopulmonary infections	Altered Intercellular Communication	It is hypothesized that BRVO occurred secondary to raised fibrinogen levels, a common feature in CF resulting from chronic pulmonary infection and inflammation.	24584306
Inflammation, Elastosis perforans serpiginosa, Anorexia	Altered Intercellular Communication	Anthropometrics reveal depleted fat and lean body mass in EPS patients, which might be a result of anorexia and inflammation, and the reason that albumin was not an accurate marker of nutrition.	24584612
Inflammation, Peritonitis, Elastosis perforans serpiginosa	Altered Intercellular Communication	We observed no differences in baseline data between the groups, but the group with EPS had been on PD longer (84 +- 53 months vs 39 +- 20 months, p = 0.002) and had a higher cumulative number of days of peritoneal inflammation from peritonitis (17.2 +- 11.1 days vs 9.8 +- 7.9 days, p = 0.015).	24584614
Infarction, Inflammation, Malignant Neoplasms, Necrosis	Altered Intercellular Communication	The cytopathologic features of infarction are necrosis and worrisome nuclear features, which are often misinterpreted as either inflammation or malignancy.	24585349
Inflammation	Altered Intercellular Communication	Increased serum globulin, a positive phase reactant of inflammation, was found significant independent risk factor for development of serous DME.	24585366
Inflammation, Cardiovascular Diseases, Dyslipidemias, Depressed mood, Disease	Altered Intercellular Communication	We conclude that this study contributes the first evidence of a correlation between marked dyslipidemia and worsened Cu/Zn ratios in HPs, implying an increased risk of diseases associated with elevated oxidative stress, inflammation, and depressed immune function, such as cardiovascular diseases.	24585396
Inflammation, Leucocytic infiltrate, Squamous cell carcinoma of the head and neck	Altered Intercellular Communication	Monocyte chemotactic protein-1 (MCP-1) recruits monocytes and macrophages to inflammation sites, and inflammatory infiltration correlates with the progression of head and neck squamous cell carcinoma (HNSCC).	24586454
Communicable Diseases, Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Inflammation and infection have been noted to increase stroke risk.	24586739
Inflammation, Dyslipidemias, HIV Infections, Atherosclerosis	Altered Intercellular Communication	The increased immune activation and inflammation of chronic HIV-infection and the characteristic dyslipidemias associated with HIV infection and antiretroviral therapy (ART) contribute to an increased risk of atherosclerotic vascular disease among HIV-infected adults.	24586854
Inflammation, Sleep Apnea, Obstructive, GDC Comorbidity Terminology, Osage language	Altered Intercellular Communication	Obstructive sleep apnea (OSA) is associated with systemic inflammation and induces various comorbid medical diseases.	24586942
Inflammation	Altered Intercellular Communication	Inflammation and adverse remodeling of the extracellular matrix may be involved in the pathogenesis.	24586994
Prostate, Carcinogenesis, Acute and chronic inflammation	Altered Intercellular Communication	Recent reports on Propionibacterium acnes (P. acnes) suggest that this bacterium is prevalent in the prostate, is associated with acute and chronic prostatic inflammation, and might have a role in prostate carcinogenesis.	24587325
Inflammation	Altered Intercellular Communication	The number of stromal macrophages with the bacterium correlated with the grade of chronic inflammation in both the PZ and TZ areas and with the grade of acute inflammation in the TZ area.	24587325
intraepithelial, Inflammation, Prostate, Prostate carcinoma	Altered Intercellular Communication	Immunohistochemical analysis with a novel monoclonal antibody for detecting P. acnes in the prostate suggested that intraepithelial P. acnes infection in non-cancerous prostate glands and inflammation caused by the bacterium may contribute to the development of prostate cancer.	24587325
Mental impairment, Neurotransmitters, Movement Disorders	Altered Intercellular Communication	This important and treatable neurotransmitter disorder must be considered in patients with a complex movement disorder with diurnal fluctuations with or without intellectual impairment.	24588500
Inflammation, Dental Plaque	Altered Intercellular Communication	Mediators of inflammation may control LOX expression in plaques and hence plaque stability.	24588843
Dyslexia, Asymmetry	Altered Intercellular Communication	PCDH11X, expressed in brain is implicated in cell-cell communication, verbal ability, cerebral asymmetry, and dendritic synaptic plasticity, may be regarded as a new candidate gene for dyslexia.	24591081
Granulomatous inflammation, AAVS1 gene, Vasculitis, CTCAE	Altered Intercellular Communication	Previous studies have reported that circulating HMGB-1 levels in patients with active antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) were associated with renal manifestations and burdens of granulomatous inflammation.	24591411
Tissue damage	Altered Intercellular Communication	High mobility group box 1 (HMGB-1), a kind of proinflammatory mediator, is associated with inflammatory conditions and tissue damage.	24591411
Degenerative polyarthritis, Inflammation, Obesity	Altered Intercellular Communication	Obesity is a major risk factor for the development of osteoarthritis (OA) that is associated with a state of low-grade inflammation and increased circulating levels of adipokines and free fatty acids (FFAs).	24591481
Inflammation, Periodontitis, Attachment (action), Periodontal Diseases	Altered Intercellular Communication	Chronic periodontitis (CP) is a multifactorial complex periodontal disease involving immune response, inflammation, alveolar bone resorption, and attachment loss.	24592910
Inflammatory Bowel Diseases, Inflammation, Sacroiliitis, Intestinal Diseases	Altered Intercellular Communication	Other factors such as type of IBD, disease duration and localisation of IBD, surgery history, biological inflammation, bowel disease activity and treatment were not associated with sacroiliitis.	24593050
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Although data suggest that the ratio of leptin/adiponectin correlates with insulin resistance and predicts cardiovascular disease (CVD), there is scanty data on the relationship between the retinol-binding protein-4 (RBP4)/adiponectin ratio with insulin resistance and inflammation.	24593134
Abnormal renal function, Fever	Altered Intercellular Communication	Colchicine resulted in not only an amelioration of the acute febrile attacks of FMF inflammation, but also an improvement in kidney dysfunction due to AA amyloidosis.	24593212
Inflammation	Altered Intercellular Communication	Moreover, inflammation of the vascular walls and an aneurism in the right subclavian artery were observed on MRI.	24593213
Inflammation, Spanish Language	Altered Intercellular Communication	We recommended that it is important to evaluate the aortic involvement in late-onset SpA patients, when elevated systemic inflammation is observed.	24593213
Fibrosis Assessment, Myocarditis	Altered Intercellular Communication	Subclinical myocardial inflammation and diffuse fibrosis are common in systemic sclerosis--a clinical study using myocardial T1-mapping and extracellular volume quantification.	24593856
Fibrosis Assessment, Myocarditis	Altered Intercellular Communication	Diffuse myocardial fibrosis can be detected non-invasively by T1 and extracellular volume (ECV) quantification, while focal myocardial inflammation and fibrosis may be detected by T2-weighted and late gadolinium enhancement (LGE), respectively, using cardiovascular magnetic resonance (CMR).	24593856
Sample Size Calculation, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	SSc patients had significantly higher native myocardial T1 values (1007 +- 29 vs. 958 +- 20 ms, p < 0.001), larger areas of myocardial involvement by native T1 >990 ms (median 52 vs. 3% in controls) and expansion of ECV (35.4 +- 4.8 vs. 27.6 +- 2.5%, p < 0.001), likely representing a combination of low-grade inflammation and diffuse myocardial fibrosis.	24593856
Sample Size Calculation, Myocarditis	Altered Intercellular Communication	Cardiac involvement is common in SSc even in the absence of cardiac symptoms, and includes chronic myocardial inflammation as well as focal and diffuse myocardial fibrosis.	24593856
Communicable Diseases, Pancreatic stone, Inflammation	Altered Intercellular Communication	Pancreatic stone protein (PSP)/regenerating protein 1-alpha (reg) is associated with inflammation, infection, and other disease-related stimuli.	24594294
Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Imaging of the vulnerable carotid plaque: biological targeting of inflammation in atherosclerosis using iron oxide particles and MRI.	24594295
Inflammation, Dental Plaque, Atherosclerotic lesion	Altered Intercellular Communication	Inflammation is a key process in plaque destabilization and the propensity of atherosclerotic lesions to cause clinical sequelae.	24594295
Inflammation	Altered Intercellular Communication	There is currently no clinical imaging technique available to assess the degree of inflammation associated with plaques.	24594295
Inflammation, atherosclerotic	Altered Intercellular Communication	Inflammation associated with human ex vivo atherosclerotic plaques could be imaged using dual antibody-conjugated SPIO by MRI.	24594295
Inflammation, Dental Plaque	Altered Intercellular Communication	The asymptomatic plaque population exhibited heterogeneity in terms of inflammation.	24594295
Myositis, CTCAE 5.0, Myositis	Altered Intercellular Communication	Sporadic inclusion body myositis (sIBM), the most frequent myositis in elderly patients, is characterized by the presence muscle inflammation and degeneration.	24594700
Pneumonitis	Altered Intercellular Communication	Moreover, the presence of either bilateral lung inflammation or pulmonary consolidation on chest imaging on admission was related with fatal outcome (OR = 7.00; 95%CI, 1.10-44.61).	24595034
Autoimmune Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	IL-17A has been shown to be a key mediator of inflammation in autoimmune diseases, transplant rejection and cancers.	24595078
Inflammation, Postoperative Period	Altered Intercellular Communication	This paradox may indicate that the contribution of inflammation to postoperative sequalae is less than commonly thought or that systemic doses are too low in their local concentration.	24595228
Inflammation, Erythema	Altered Intercellular Communication	Local skin reactions, consisting of mild to moderate erythema and flaking/scaling, were significantly improved by 1 week after peak inflammation and were not treated in most patients.	24595570
Inflammation	Altered Intercellular Communication	Magnetic resonance imaging (MRI) of the optic nerve revealed an inflammation of the left optic nerve with chiasmatic involvement, without any encephalic or medullar lesion.	24596142
Orbital Pseudotumor	Altered Intercellular Communication	Resolution of idiopathic granulomatous orbital inflammation with intraorbital triamcinolone.	24596409
Orbital Pseudotumor	Altered Intercellular Communication	Biopsy and histopathology of the lesion identified idiopathic granulomatous orbital inflammation.	24596409
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Such treatment may thus form an alternative to oral corticosteroid therapy in the management of granulomatous orbital inflammation.	24596409
Inflammation, Swelling	Altered Intercellular Communication	Initially, the inflammation was controlled successfully with corticosteroids but the swelling persists to this day.	24597112
Calcinosis, Aortic Valve Stenosis	Altered Intercellular Communication	Taken together, these results indicate that inflammatory signaling through LTB4 may be more closely linked to calcification and aortic stenosis than signaling through TGF-beta1 and MPs.	24597398
Neurogenic Inflammation, Hypersensitivity, Edema	Altered Intercellular Communication	Neurogenic inflammation involves vasodilation, oedema and sensory nerve hypersensitivity.	24597665
Malignant mesothelioma, Carcinogenesis, Inflammation	Altered Intercellular Communication	Asbestos causes lung cancer and malignant mesothelioma, and chronic inflammation is considered to participate in carcinogenesis.	24598051
Carcinogenesis	Altered Intercellular Communication	Reactive oxygen/nitrogen species are generated in biological systems under inflammatory conditions and may contribute to carcinogenesis by causing DNA damage.	24598051
Inflammation, Squamous cell carcinoma, Smoking, Adenocarcinoma, Small cell carcinoma of lung	Altered Intercellular Communication	We analyzed the presence of distinct inflammatory cells and the macrophage activation phenotype together with the levels of vascular endothelial growth factor (VEGF) and interleukin 8 (IL-8) within BALF from 54 smoking lung cancer patients including 36 squamous cell carcinoma (SCC), 9 adenocarcinoma (AC), and 9 small cell lung cancer (SCLC) in comparison with those from 13 non-smoking and 7 smoking patients with nonspecific chronic inflammation and 8 non-smoking normal controls.	24598169
Inflammation, Carcinoma of lung	Altered Intercellular Communication	We found a significantly lower percentage of total macrophages and a much higher percentage of neutrophils among all inflammatory cells in BALF from lung cancer and non-specific chronic inflammation patients.	24598169
Inflammation	Altered Intercellular Communication	Our results suggest that the detection of infiltrating inflammatory cells and pro-angiogenic factors in BALF will be helpful for diagnosis of cancerous inflammation in lungs.	24598169
palladium, Inflammation, Tissue injury, Peritonitis	Altered Intercellular Communication	Taken together these data suggest that the TWEAK/Fn14 system may promote inflammation and tissue injury during peritonitis and PD.	24599047
Inflammation, Demographics Domain, Diabetes Mellitus, Coronary Artery Disease	Altered Intercellular Communication	Both coronary artery disease (CAD) and diabetes mellitus (DM) are associated with inflammation.	24599246
Malignant Neoplasms	Altered Intercellular Communication	The COX2 rs5277 (306G>C) polymorphism has been associated with inflammation-associated cancers.	24599585
Vasculitis, CTCAE	Altered Intercellular Communication	These results suggest that, upon inflammatory conditions in GPA, renal MECs may contribute to the recruitment and activation of NK cells in the target vessel wall, which may participate in the necrotizing vasculitis of the kidney during this disease.	24600034
Inflammation, Hyperkeratosis	Altered Intercellular Communication	The most common complications observed were chronic inflammation (54.2%) and hyperkeratosis (48.2%).	24601858
Chronic inflammation, Communicable Diseases, Chronic osteomyelitis, Cerebrovascular accident, cyclophosphamide/methotrexate/vincristine protocol	Altered Intercellular Communication	In this study, it was assessed whether chronic osteomyelitis (COM), an infectious disease with chronic inflammation, increases stroke risk.	24602152
Inflammation, Demyelination, Axonal loss, MS gene	Altered Intercellular Communication	Chronic demyelination, on-going inflammation, axonal loss and grey matter neuronal injury are likely pathological processes that contribute to disease progression in multiple sclerosis (MS).	24602691
Eosinophilic inflammation	Altered Intercellular Communication	The results obtained in this in vitro model suggest that FF may reduce upper airway eosinophilic inflammation through decreasing cytokine secretion from epithelial cells and reducing eosinophil survival.	24603043
Inflammation	Altered Intercellular Communication	If symptoms and inflammation persist and no narrowing is appreciated, an elemental diet can be considered; however, the long-term use of this in older children and adults may be difficult.	24603397
Inflammation, Chronic disease, Obesity, Weight Gain, Overweight	Altered Intercellular Communication	Inflammation may constitute an underlying mechanism for increased risk of developing chronic diseases in later years, but few prospective studies have assessed the influence of low-grade inflammation on body weight gain, particularly among children in low- to middle-income settings with lower prevalence of overweight and obesity.	24603645
Inflammation, Skin, Human	Altered Intercellular Communication	Characterisation of leukocytes in a human skin blister model of acute inflammation and resolution.	24603711
Inflammation	Altered Intercellular Communication	There is an increasing need to understand the leukocytes and soluble mediators that drive acute inflammation and bring about its resolution in humans.	24603711
Inflammation	Altered Intercellular Communication	Quantification of NETs in bronchial aspirates may provide a new indicator of inflammation.	24603817
Inflammation, Pathologic Neovascularization, Fibrosis Assessment, Cicatrization	Altered Intercellular Communication	Histopathology analysis revealed inflammation, scarring, neovascularisation and extensive leaflet fibrosis in diseased mitral valve.	24603967
Inflammation, Diabetic Retinopathy, GDC Disease Response Terminology	Altered Intercellular Communication	Inflammation may contribute to the pathogenesis of diabetic retinopathy (DR).	24604308
Inflammation	Altered Intercellular Communication	Vitamin D deficiency is associated with inflammation in older Irish adults.	24606079
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Inadequate vitamin D status is common within elderly populations and may be implicated in the etiology of autoimmune disease and inflammation.	24606079
Hyperlipidemia, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Compared with lean control subjects, those with Type 2 diabetes had more deleterious profiles of hyperlipidaemia, vitamin D deficiency, inflammation and maximal oxygen uptake relative to body mass.	24606573
Airway structure, Asthma, IL13 gene	Altered Intercellular Communication	Ongoing allergic rhinitis impairs asthma control by enhancing the lower airway inflammation.	24607045
Airway structure, Asthma, IL13 gene, MS4A2 wt Allele	Altered Intercellular Communication	This observational study of patients with atopy indicates that the ongoing allergic rhinitis is related to worsening of asthma by enhancing the lower airway inflammation.	24607045
Inflammation	Altered Intercellular Communication	Chronic cadmium exposure may cause disease through induction of systemic oxidative stress and inflammation.	24607659
Inflammation, Chronic sinusitis, IL13 gene	Altered Intercellular Communication	Causes of use included acute inflammation (n=6), chronic rhinosinusitis (n=2), and allergic rhinitis (n=20) and unknown cause (n=5).	24608651
Inflammation	Altered Intercellular Communication	The patient exhibited an extreme increase in interleukin-17 (IL-17), one of the major regulatory cytokines for inflammation and neutrophil migration.	24609719
Pain Distress Question, Inflammation	Altered Intercellular Communication	Thus, we carried out a 1 week clinical trial to examine the extent to which UP446-a natural proprietary blend of S. baicalensis and A. catechu (UP446)-decreases knee joint pain, mobility, and biomarkers of inflammation in comparison to naproxen.	24611484
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	TWT was correlated with macroscopic IBD scores and histological inflammation scores.	24612000
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	There was a strong correlation of TWT with histological inflammation scores (UC: r = 0.43; CD: r = 0.69).	24612000
Ulcerative Colitis, Colitis	Altered Intercellular Communication	EUS can differentiate active UC from CD and quantify the level of colonic inflammation.	24612000
Periodontitis, atherosclerotic	Altered Intercellular Communication	Chronic periodontitis (CP) and atherosclerotic and aortic aneurysmal vascular diseases (VD) are inflammatory conditions that share a number of predisposing factors.	24612355
Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Adhesion molecules CD146 and its soluble form strongly correlated with the development of inflammation of atherosclerosis and plaque instability.	24612514
Renal Insufficiency, Inflammation	Altered Intercellular Communication	These cases can present significant technical and management challenges secondary to the underlying pathology, associated anatomic inflammation, and impaired functional status.	24612704
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Serum inflammation markers predicting successful initial catheter ablation for atrial fibrillation.	24613042
Idiopathic Interstitial Pneumonias, Fibrosis Assessment, Pneumonia, Interstitial, Interstitial inflammation	Altered Intercellular Communication	Idiopathic interstitial pneumonia (IIP) is characterized by chronic interstitial inflammation and fibrosis.	24613046
Arterial Stiffness, Inflammation, Diabetes Mellitus, Insulin-Dependent	Altered Intercellular Communication	No association of dietary fiber intake with inflammation or arterial stiffness in youth with type 1 diabetes.	24613131
Arterial Stiffness, Inflammation, Diabetes Mellitus, Insulin-Dependent, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8	Altered Intercellular Communication	To examine the association of dietary fiber intake with inflammation and arterial stiffness among youth with type 1 diabetes (T1D) in the US.	24613131
Arterial Stiffness, Inflammation	Altered Intercellular Communication	In multivariable analyses, fiber intake was not associated with inflammation or arterial stiffness.	24613131
Inflammation, Vascular Stiffness, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8	Altered Intercellular Communication	Among youth with T1D, fiber intake does not meet recommendations and is not associated with measures of systemic inflammation or vascular stiffness.	24613131
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Association between seven single nucleotide polymorphisms involved in inflammation and proteolysis and abdominal aortic aneurysm.	24613192
Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Patients with malignancy, pregnancy, concurrent inflammatory or infectious diseases, or concomitant use of any medication affecting inflammation status were excluded.	24613294
Inflammation, Impaired	Altered Intercellular Communication	The ability of HDL to attenuate endothelial inflammation is impaired in acute MI, and this metric of HDL function may serve as a predictor of new MACE, even independent of HDL cholesterol and apolipoprotein A-I.	24613518
Chronic inflammation of orbit, Inflammation	Altered Intercellular Communication	Biopsy-proven chronic orbital inflammation was present in all patients; this resembled reactive lymphoid hyperplasia (RLH) in 7 patients and immunoglobulin (Ig) G4-related sclerosing inflammation in 7 patients.	24613826
Tissue damage, Inflammation	Altered Intercellular Communication	Recovery after cardiac surgery is a complex process that has to compensate for both individual variability and extensive tissue damage in the context of systemic inflammation.	24614541
Inflammation	Altered Intercellular Communication	Protein glycosylation is essential in many steps of the inflammatory cascade, but due to technological limitations the role of individual variation in glycosylation in systemic inflammation has not been addressed until now.	24614541
Inflammation	Altered Intercellular Communication	Our results indicate that individual variation in IgG glycosylation changes during acute systemic inflammation associates with increased mortality risk and indicates new avenues for the development of personalized diagnostic and therapeutic approach.	24614541
Nasolacrimal Duct Obstruction, Inflammation, Lacrimal Duct Obstruction	Altered Intercellular Communication	Etiologies of lacrimal obstruction requiring a dacryocystorhinostomy (DCR) have been reviewed previously but most commonly are thought to result from "primary acquired" nasolacrimal duct obstruction, a process of chronic inflammation in a narrowed duct.	24614546
Inflammation, Fibrosis Assessment, Hepatitis, Chronic	Altered Intercellular Communication	The rate of clinical diagnosis matching the pathological diagnosis for fibrosis was higher than for inflammation (83.33 vs 54.76%), especially in moderate (83.33 vs 26.67%) and severe chronic hepatitis (66.67 vs 16.67%).	24615102
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In HBV carriers, the degree of inflammation and fibrosis in most cases was mild, and the younger the patients, the higher the ratios of G0 and S0.	24615102
Inflammation, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	The clinical diagnosis was correct in most cases, especially for inflammation and in mild chronic hepatitis; the patients who were diagnosed as HBV carriers actually already had inflammation and fibrosis.	24615102
Inflammation, Pulmonary granuloma, Fever, CTCAE, Cystitis	Altered Intercellular Communication	The most frequent complications of such treatment include fever and urinary bladder inflammation, while serious complications of haematogenous organ inflammation, especially inflammation of the lungs with the formation of pulmonary caseosus granulomas, are rarely seen.	24615200
Stomach Carcinoma	Altered Intercellular Communication	The most studied genetic susceptibility factors involved in gastric carcinoma (GC) risk are polymorphisms in the inflammation-linked genes interleukin 1 (IL1) B and IL1RN.	24615437
Inflammation, Metabolic Diseases	Altered Intercellular Communication	Serum plasmalogens (Pls) (1-O-alk-1'-enyl-2-acyl glycerophospholipids) are of particular interest for studies on metabolic disorders associated with oxidative stress and chronic inflammation.	24616482
Inflammation, Crohn Disease	Altered Intercellular Communication	The impact of inflammation on vitamin D and mineral metabolism has not been well-characterized in Crohn's disease (CD).	24617709
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The interaction between inflammation and cancer is well established.	24617829
Inflammation	Altered Intercellular Communication	Surrogate markers of systemic inflammation, such as the neutrophil/lymphocyte ratio (NLR), may be associated with the long-term oncological outcome.	24617829
ARCN1 gene, Inflammation, Lung Injury, Exacerbation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) exacerbations are accompanied with increased systemic inflammation, which accelerate the pulmonary function injury and impair the quality of life.	24618290
Inflammation, Exacerbation	Altered Intercellular Communication	The CAT is associate with the changes of systemic inflammation following COPD exacerbations.	24618290
Human papilloma virus infection, Immunocompromised Host	Altered Intercellular Communication	Rather in contemporary times, common risk factors include HPV infection, immunocompromised states, and chronic scrotal inflammatory conditions.	24618607
APP gene, Vasculitis, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Chronic vascular inflammation is a key hallmark in the pathogenesis of abdominal aortic aneurysm (AAA).	24618883
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Subclinical inflammation may be a mechanism linking air pollution with diabetes.	24619127
Inflammation, Neuronal loss in central nervous system, Cerebral atrophy	Altered Intercellular Communication	The successfully engrafted younger sibling had less brain inflammation, cortical atrophy, and neuronal loss on neuro-imaging and neuropathology compared to the untreated older sister.	24619150
White matter	Altered Intercellular Communication	Although HSCT did not halt the course of ACOX1 deficiency, it reduced the extent of white matter inflammation in the brain.	24619150
Pterygium Of Conjunctiva And Cornea, Conjunctivitis	Altered Intercellular Communication	Pterygium recurrence, ocular discomfort, persistent conjunctival inflammation, and graft complications were evaluated postoperatively.	24619168
Conjunctivitis	Altered Intercellular Communication	Persistent conjunctival inflammation was also significantly higher in the summer group than in the winter group (30.4% vs. 6.2%, P = 0.022).	24619168
Inflammation, Pterygium Of Conjunctiva And Cornea, Conjunctivitis	Altered Intercellular Communication	Pterygium recurrence was significantly higher in eyes with persistent conjunctival inflammation than in eyes without inflammation (66.6% vs. 4.3%, P < 0.001).	24619168
Granulomatous inflammation	Altered Intercellular Communication	Histological investigations showed an intense granulomatous inflammation with severe destruction of the parenchyma.	24619528
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Atypical distribution of inflammation in newly diagnosed ulcerative colitis is not rare.	24619632
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Appendiceal orifice inflammation (AOI) is a common 'skip lesion' in patients with ulcerative colitis (UC).	24619632
Inflammation	Altered Intercellular Communication	Prospective studies showed that chronic subclinical inflammation is a predictor of T2DM.	24619654
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	These data suggest that a value of a 1-h OGTT glucose >=155 mg/dl may be helpful to identify a subset of normal glucose tolerance individuals at risk for chronic subclinical inflammation, a predictor of T2DM, and cardiovascular diseases.	24619654
Inflammation, Paralysed, Herpes Simplex Infections, herpesvirus 3, human, Bell Palsy	Altered Intercellular Communication	The reactivation of latent herpes simplex virus (HSV) or varicella-zoster virus (VZV) with subsequent inflammation and entrapment of the facial nerve in the narrow labyrinthine segment has been implicated as a cause of facial paralysis, but the active role of these viruses in Bell's palsy is still discussed.	24619963
Communicable Diseases, Periodontitis, atherosclerotic	Altered Intercellular Communication	A persistent infection, such as chronic periodontitis, may influence changes in the systemic levels of HsCRP, LDL and HDL, which potentially have an impact on inflammation-associated atherosclerotic processes, such as CAD.	24620793
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Increased oxidative stress and inflammation has a role in the pathogenesis of chronic obstructive pulmonary disease (COPD).	24621680
Neurogenic Inflammation, Pain Disorder	Altered Intercellular Communication	The authors hypothesized that capsaicin-induced pain and neurogenic inflammation (skin perfusion and flare area) are increased in patients with complex regional pain syndrome compared with that in controls.	24621686
Pain Distress Question, Neurogenic Inflammation	Altered Intercellular Communication	The flare response to capsaicin was normal, suggesting that the increased pain response was not due to increased neurogenic inflammation.	24621686
Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	Genome-wide association studies (GWAS) have identified single-nucleotide polymorphisms (SNPs) associated with CRP concentrations and inflammation-related traits such as cardiovascular disease, type 2 diabetes mellitus, and obesity.	24622110
Inflammation, Heart failure	Altered Intercellular Communication	Soluble ST2 (sST2), a biomarker related to inflammation, is associated with outcomes of patients with heart failure.	24622243
Airway structure, ARCN1 gene, Asthma	Altered Intercellular Communication	However, airway inflammation is generally less responsive to steroids in COPD than in asthma.	24622644
Acute myocardial infarction, Upper Respiratory Infections	Altered Intercellular Communication	Three participants died: two before randomisation and one in the basal-bolus group (due to severe acute myocardial infarction and respiratory tract inflammation).	24622667
Plaque, Atherosclerotic	Altered Intercellular Communication	Imaging atherosclerotic plaque inflammation via folate receptor targeting using a novel 18F-folate radiotracer.	24622812
Inflammation, Rupture	Altered Intercellular Communication	In nascent lesions, they coordinate the scavenging of lipids and cellular debris to define the likelihood of plaque inflammation and eventually rupture.	24622812
Inflammation	Altered Intercellular Communication	Selectively targeting FR-b-positive macrophages through folate-based radiopharmaceuticals may be useful for noninvasive imaging of plaque inflammation.	24622812
Inflammation, Non-Small Cell Lung Carcinoma, Carcinoma of lung	Altered Intercellular Communication	Although the alterations of lipid profile in lung cancer have been documented, the prognostic value of serum HDL-C level and its correlation with inflammation in NSCLC remain unknown.	24625581
Autoimmune Diseases of the Nervous System	Altered Intercellular Communication	DARC shuttles inflammatory chemokines across the blood-brain barrier during autoimmune central nervous system inflammation.	24625696
Rheumatoid Arthritis, Tumor necrosis, Inflammation	Altered Intercellular Communication	In rheumatoid arthritis it is used because the cytokines that cause inflammation in this disease are regulated by tumor necrosis factor alpha and IL-1.	24626663
Inflammation, Osage language	Altered Intercellular Communication	The subgroup of patients with OSA and RFL have several factors that promote inflammation of the upper airway.	24626885
Inflammation, Acute heart failure	Altered Intercellular Communication	Previous studies have demonstrated the role of inflammation in acute heart failure.	24626945
Inflammation, Ischemic stroke	Altered Intercellular Communication	High-sensitivity C-reactive protein and interleukin-6-dominant inflammation and ischemic stroke risk: the northern Manhattan study.	24627113
Inflammation, Hyperuricemia, Hypertension, CTCAE, Metabolic Syndrome X	Altered Intercellular Communication	Interaction of inflammation, hyperuricemia, and the prevalence of hypertension among adults free of metabolic syndrome: NHANES 2009-2010.	24627417
Inflammation, Hypertension, CTCAE, Hyperuricemia	Altered Intercellular Communication	Hyperuricemia and markers of inflammation are correlated with the risk for hypertension.	24627417
Airway structure, Asthma	Altered Intercellular Communication	Th17-mediated neutrophilic airway inflammation has been implicated in decreased response to glucocorticoids in asthma.	24627531
Inflammation, Asthma	Altered Intercellular Communication	We show that glucocorticoids enhance CCL20 production by bronchial epithelium, which may constitute a novel mechanism in Th17-mediated glucocorticoid-insensitive inflammation in asthma.	24627531
Guinea (geographic area), Intraepithelial Neoplasia	Altered Intercellular Communication	Our results showed that 45 cases of intraepithelial neoplasia disappeared when chronic inflammation left, and 33 cases were given the original diagnoses and two cases developed into high-grade GIN.	24627924
Inflammation, Guinea (geographic area)	Altered Intercellular Communication	Results showed four cases of chronic inflammation, 11 cases with original diagnoses maintained, and three cases of high-grade GIN.	24627924
Intestinal metaplasia, Guinea (geographic area)	Altered Intercellular Communication	GIN occurred frequently in patients with more severe pathological inflammations under endoscope, which also had certain correlations with intestinal metaplasia.	24627924
Airway structure	Altered Intercellular Communication	Asian dust storms (ADS) contain various airborne particles that may augment airway inflammation by increasing the level of interleukin-8.	24628524
Airway structure	Altered Intercellular Communication	ADS airborne particles may increase airway inflammation through enhancement of interleukin-8 transcriptional activity.	24628524
vascular inflammations	Altered Intercellular Communication	Pentraxin 3 (PTX3) is probably a specific marker of vascular inflammation.	24628740
Inflammation, Atherosclerosis	Altered Intercellular Communication	These results support the hypothesis that PTX3 reflects different aspects of inflammation than CRP, and may provide additional insights into the development and progression of atherosclerosis.	24628740
Inflammation, Stomach Carcinoma, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Helicobacter pylori infection is a strong risk factor for gastric cancer, likely due to the extensive inflammation in the stomach mucosa caused by these bacteria.	24628819
Inflammation, Atherosclerosis	Altered Intercellular Communication	Neutrophil (PMN) leukocytes participate to the initial phases of atherosclerosis through the release of Interleukin 8 (CxCL8; IL-8) that contribute to amplification of inflammation.	24629144
Type 1 Autoimmune Pancreatitis, Colitis	Altered Intercellular Communication	Inflammation of colon adenoma in the setting of type 1 autoimmune pancreatitis.	24629174
Inflammation, Fibrosis Assessment, Colonic adenomas, Waldenstrom Macroglobulinemia, Adenoma, Phlebitis	Altered Intercellular Communication	Both colon adenomas from patients with (IgG4 adenomas) and without (Non-IgG4 adenomas) IgG4-RD were characterized by moderate to severe lymphoplasmacytic and eosinophilic inflammation without fibrosis or phlebitis.	24629174
Inflammation, Fatty degeneration, Shwachman syndrome, Neoplasms	Altered Intercellular Communication	The tumor was intermingled with two pathological changes characteristic of Shwachman-Diamond syndrome: fatty degeneration of the pancreas and inflammation of the villous stroma of the duodenum.	24629175
Inflammation, Carcinogenesis	Altered Intercellular Communication	Considering that SBDS protein regulates mitosis and its suppression causes genomic instability, this case might provide an example of carcinogenesis based on genomic instability, together with degenerative changes and chronic inflammation, at a very young age.	24629175
Inflammation, ME1 gene, Depression, CTCAE	Altered Intercellular Communication	Clinical investigators are encouraged to assess markers of inflammation and review detailed information on risk factors such as waist circumference for MeS in patients with depression.	24629898
Iron deficiency, Inflammation, Normocytic anemia	Altered Intercellular Communication	RTD was associated with normocytic anemia, accompanying iron deficiency and inflammation.	24630338
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Neutrophil/lymphocyte ratio (NLR), a marker of host inflammation, is prognostic in several cancers but has not been reviewed in large BTC series, or advanced BTC (ABTC) at diagnosis.	24630393
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Pretreatment neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that has been associated with adverse survival in a variety of malignancies.	24630414
Seizures, Abscess, Cerebral dysfunction	Altered Intercellular Communication	Brain abscesses often cause symptoms of brain dysfunction, including seizures, suggesting interference with normal neurotransmission.	24632003
Inflammation, Fatigue	Altered Intercellular Communication	Fatigue has been associated with inflammation and cytokine activity among adults, but this relationship has not been evaluated among adults living with HIV.	24632226
Inflammation, Fatigue	Altered Intercellular Communication	This study strengthens the evidence for an association between inflammation and fatigue.	24632226
Pneumonitis	Altered Intercellular Communication	We hypothesize that selective pulmonary perfusion (sPP) of the lungs leads to a reduction of pulmonary inflammation and a better clinical outcome.	24632426
Inflammation, Myocardial Ischemia	Altered Intercellular Communication	Also, we tested whether normal food intake or inflammation influenced lipoprotein(a)'s ability to predict ischemic heart disease.	24632508
Inflammation, Electrocardiogram: myocardial infarction (finding), Myocardial Ischemia	Altered Intercellular Communication	The ability of elevated lipoprotein(a) levels to predict ischemic heart disease and myocardial infarction in the general population was not affected by normal food intake or inflammation.	24632508
Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	Pulmonary coagulopathy may play a pathogenetic role in acute respiratory distress syndrome (ARDS), by contributing to alveolocapillary inflammation and increased permeability.	24632673
Drug Eruptions, Inflammation, Gingival Overgrowth	Altered Intercellular Communication	Gingival overgrowth (GO) frequently occurs in transplant patients receiving immunosuppressive drugs such as cyclosporine and this gingival inflammation might play an important role in the pathogenesis of drug-induced GO.	24632797
Inflammation, Behavioral Symptoms, Breast Carcinoma	Altered Intercellular Communication	Elevated inflammation predicts behavioral symptoms, disease progression, and mortality in patients with breast cancer and breast cancer survivors, although predictors of inflammation remain largely unknown.	24632893
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	However, little research has examined the association between childhood adversity and inflammation in the context of cancer, where inflammation is particularly relevant for health.	24632893
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Childhood adversity was associated with elevated markers of inflammation in breast cancer survivors, with potential negative implications for health and well-being.	24632893
Inflammation	Altered Intercellular Communication	Pentraxin 3 (PTX3) is an inflammatory protein produced at inflammation sites such as leukocytes and vascular endothelial cells.	24632958
Squamous cell carcinoma, Malignant Neoplasms, Childhood Angiosarcoma	Altered Intercellular Communication	Morphologically, PH may be confused with other lesions, from benign vasoformative neoplasms and reactive inflammatory conditions to malignancies such as angiosarcoma or squamous cell carcinoma.	24632981
Inflammation, Pain Distress Question, Gout	Altered Intercellular Communication	The administration of systemic corticosteroids relieved the joint inflammation and pain; however, the urate level increased to 28 mg/dL and the gout attacks recurred.	24633032
Diverticulosis of the duodenum, Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	Chronic inflammation predisposing to cancer metastasis: lesson learned from a chronically embedded foreign body in a duodenal diverticulum.	24633596
Inflammation, Chordoid meningioma, Chronic fatigue	Altered Intercellular Communication	Chordoid meningioma in an adult patient presenting with chronic fatigue and systemic inflammation.	24635333
Inflammation, Anemia, Neoplasms	Altered Intercellular Communication	Aspecific neurologic symptoms and biochemical indices of inflammation and anaemia triggered an MRI, revealing a tumor with compression of the medulla oblongata.	24635333
Inflammation, Weight decreased	Altered Intercellular Communication	Aerobic exercise and weight loss reduce vascular markers of inflammation and improve insulin sensitivity in obese women.	24635342
vascular inflammations, Obesity	Altered Intercellular Communication	Obesity and insulin resistance worsen markers of systemic and vascular inflammation.	24635342
Inflammation, Neurologic Symptoms	Altered Intercellular Communication	However, no correlation was found between the histological evidence and the degree of inflammation and neurological symptoms.	24635921
Inflammation, Neurologic Deficits, Pain Distress Question	Altered Intercellular Communication	However, the neuroradiological and histological evidence of peridiscal inflammation was not correlated with the severity of pain or sensorimotor deficits in our patients.	24635921
Inflammation, Intervertebral Disk Displacement	Altered Intercellular Communication	Additional research is needed because the occurrence of local inflammation may indicate an ongoing degradation of herniated fragments and thus be helpful in therapeutic decision-making.	24635921
Ulcer, Inflammation, Colitis	Altered Intercellular Communication	The extent of inflammation is a predictor for pouch-related complications in ileal pouches in patients with ulcerative or indeterminate colitis.	24635999
Inflammation	Altered Intercellular Communication	The presence of extension of the inflammation into the muscularis propria of the resected specimen was associated with an increased risk of pouch-related complications (P = 0.01).	24635999
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The extension of inflammation into the muscularis propria appears to predict pouch-related complications following restorative proctocolectomy for UC or IC.	24635999
Acute inflammation, Obesity	Altered Intercellular Communication	Obesity is associated with acute inflammation in a sample of adolescents.	24636574
Inflammation, Adolescent Obesity	Altered Intercellular Communication	To evaluate whether circulating neutrophils, markers of acute inflammation, are associated (quantitatively and qualitatively) with adolescent obesity and whether leptin modulates these associations.	24636574
Inflammation	Altered Intercellular Communication	Participants with increased adiposity had higher circulating neutrophil counts, suggesting acute inflammation.	24636574
Inflammation, Lung Diseases, Interstitial, Fibrosis Assessment	Altered Intercellular Communication	Interstitial lung diseases (ILDs) form a heterogeneous group of diseases with varying degrees of inflammation and fibrosis.	24636811
Inflammation, Carotid Intima-Media Thickness	Altered Intercellular Communication	In addition, inflammation models such as carotid intima-media thickness and serum inflammatory cytokines were analyzed in 58 taxi drivers with and without co-morbidity.	24637182
Inflammation, AHSG protein, human	Altered Intercellular Communication	Fetuin-A may contribute to exercise training-induced improvements in hepatic insulin resistance, CHO utilization, and inflammation in older obese adults.	24637346
Autoimmune Diseases, Inflammation, destruction joint	Altered Intercellular Communication	RA synovial fibroblasts (RASF) actively contribute to inflammation and joint destruction in this chronic inflammatory autoimmune disease.	24638860
Inflammation, Hemorrhage, Hypertrophy	Altered Intercellular Communication	Abnormal clinical presentation in Group A included altered pigmentation (35.6%), rapid enlargement (30.5%), keratotic changes (16.9%), inflammation (7.6%), ulceration (5.1%), and hemorrhage (4.2%).	24638865
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Animal studies link PAHs to inflammation and subsequent development of diabetes mellitus.	24638887
Inflammation, Nerve Degeneration	Altered Intercellular Communication	The objective of this paper is to determine whether progressive neurodegeneration occurs in MS eyes without clinically evident inflammation.	24639478
Inflammation	Altered Intercellular Communication	In RRMS eyes without clinically evident inflammation, progressive loss of RNFLT and GCIPT occurred, supporting the need for neuroprotection in addition to suppression of autoimmune responses and inflammation.	24639478
Bronchitis	Altered Intercellular Communication	Bronchial inflammation process in elderly patients (> 60 years) was characterized by significant higher content of neutrophils and lymphocytes as well as lower proportion of alveolar macrophages.	24640699
Chronic lymphocytic inflammation, Pontine structure, Clippers, Inflammatory disorder	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disease of the central nervous system that predominantly involves the pons and cerebellum and that improves with immunosuppressive treatment.	24641246
Cystic degeneration, Focal granulomatous inflammation	Altered Intercellular Communication	We report two cases of melanocytic matricoma in two elderly women with unusual histopathological features such as cystic degeneration and focal granulomatous inflammation, which are considered to be atypical for this entity.	24641267
Inflammation, Asthma	Altered Intercellular Communication	While clinically similar to eosinophilic asthma, patients with non-eosinophilic asthma have different responses to treatment and little is known about the triggers of symptoms and inflammation.	24641293
Inflammation, Chronic inflammatory disorder	Altered Intercellular Communication	To gain insight into the specificity of the psychophysiological stress response during chronic inflammation, we assessed autonomic and neuroendocrine responses to stress in different chronic inflammatory diseases.	24641720
Psoriasis	Altered Intercellular Communication	The altered neuroendocrine stress response in patients with psoriasis suggests that stressful events might have different physiological consequences for specific patient groups with chronic inflammatory conditions, possibly adversely affecting disease status.	24641720
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Recent studies have shown that the presence of systemic inflammation correlates with poor survival in various cancers.	24641770
Inflammation	Altered Intercellular Communication	the results suggest that GAG may be related to the ongoing process of inflammation and remodeling of the dysfunctional urothelium that is present in the PBS/IC.	24642152
Communicable Diseases, Inflammation, Febrile Neutropenia, CTCAE	Altered Intercellular Communication	Distinct inflammatory mediator patterns characterize infectious and sterile systemic inflammation in febrile neutropenic hematology patients.	24642872
Tissue damage, Inflammation, Infection, Fever, CTCAE	Altered Intercellular Communication	Invasive infections and sterile tissue damage can both give rise to systemic inflammation with fever and production of inflammatory mediators.	24642872
Communicable Diseases, Noncommunicable Diseases, Inflammation	Altered Intercellular Communication	We hypothesized that it would be possible to distinguish patterns of inflammatory mediators characterizing infectious and non-infectious causes of inflammation, respectively.	24642872
Inflammation, inflammation or infection	Altered Intercellular Communication	It is possible to separate patients with infectious inflammation from those with sterile inflammation based on inflammatory mediator patterns.	24642872
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP) is a heritable biomarker of systemic inflammation and a predictor of cardiovascular disease (CVD).	24643644
Shock, Inflammation	Altered Intercellular Communication	Heat shock proteins (Hsp) are highly conserved immunomodulatory molecules upregulated when cells are exposed to stressful stimuli, such as inflammation.	24643797
Inflammation, Brain Injuries, Cerebral Ischemia	Altered Intercellular Communication	We show that infection-induced systemic inflammation mediates its effects via increasing platelet activation and microvascular coagulation in the brain after cerebral ischemia, as confirmed by reduced brain injury in response to blockade of platelet glycoprotein (GP) Iba.	24644058
Communicable Diseases, Inflammation, Atherosclerosis	Altered Intercellular Communication	S. pneumoniae infection augments atherosclerosis and exacerbates ischemic brain injury via IL-1 and platelet-mediated systemic inflammation.	24644058
Inflammation, Fracture	Altered Intercellular Communication	Fracture healing is an active process with early changes in bone and inflammation.	24644096
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	These findings suggest that residual low-grade inflammation may influence the presence of IBS-like symptoms in UC patients in remission.	24646420
Balanitis, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD), characterized by senile inflammation, is a risk factor for cardiovascular disease.	24646648
Nephrosclerosis, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Coexistence of inflammation and conduit artery dysfunction may be closely related to renal small artery sclerosis in patients with CKD.	24646648
Inflammation, Primary malignant neoplasm, Hyperplasia	Altered Intercellular Communication	Observers also chose a final diagnosis from the categories of cancer, hyperplasia, inflammation, or normal.	24646882
Inflammation	Altered Intercellular Communication	Sphingolipids can alter synovial inflammation and the repair responses of damaged joints.	24646942
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Experimental studies showed that syndecan-1 is associated with inflammation in acute myocardial infarction and remodeling.	24647119
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Multivariable regression analyses showed a positive correlation between syndecan-1 levels and markers of fibrosis and remodeling but no correlation with inflammation markers.	24647119
Inflammation	Altered Intercellular Communication	Biomarkers of one-carbon metabolism are associated with biomarkers of inflammation in women.	24647390
Inflammation	Altered Intercellular Communication	Biomarkers of inflammation are associated with PLP, RBC folate, and homocysteine in women.	24647390
Periodontitis, Gastrointestinal mucositis	Altered Intercellular Communication	Periodontitis and radiation-induced oral mucositis are both inflammatory conditions which may be associated through a common underlying dysregulation of the inflammatory response.	24647487
Inflammation, Fat-free mass, Chronic Obstructive Airway Disease	Altered Intercellular Communication	To investigate the effects of elastic tubing training compared with conventional resistance training on the improvement of functional exercise capacity, muscle strength, fat-free mass, and systemic inflammation in patients with chronic obstructive pulmonary disease.	24647863
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Intermittent oxygen deficiency in cancers promotes prolonged inflammation, continuous angiogenesis, and increased drug resistance.	24648344
Inflammation	Altered Intercellular Communication	To better characterize this inflammatory response and to link inflammation to bone degradation, the local generation of proinflammatory and osteoclast-inducing cytokines was analysed, as was systemic T cell activation.	24650243
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	HIV-infected patients on antiretroviral therapy (ART) have an increased cardiovascular disease (CVD) risk as a result of heightened inflammation and immune activation, despite at times having normal lipids and few traditional risk factors.	24650269
Inflammation, HIV Infections	Altered Intercellular Communication	This study investigated the relationship between Lp-PLA2 and markers of CVD risk, systemic inflammation, immune activation, and coagulation in HIV infection.	24650269
Inflammation, Atherosclerosis	Altered Intercellular Communication	Subclinical atherosclerosis, endothelial function, inflammation, immune activation and fasting lipids were also evaluated.	24650269
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Novel fibrosis and inflammation markers in AF are correlated with atrial remodeling.	24651058
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Several unexplained mechanisms of atrial remodeling remain, but the present study has taken the first step in elucidating the mechanisms involving fibrosis and inflammation markers.	24651058
APP gene, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	The pathogenesis of abdominal aortic aneurysm (AAA) is characterized to be inflammation-associated degeneration of vascular wall.	24651519
Inflammation, Primary lymphoid organ, Obesity	Altered Intercellular Communication	In animal model studies, obesity compromises the T-cell immune system as a result of enhanced adipogenesis in primary lymphoid organs and systemic inflammation.	24651652
Inflammation, Obesity	Altered Intercellular Communication	This population study suggests that obesity with enhanced inflammation is involved in aging of the human T-cell immune system.	24651652
Trachoma , Fibrosis Assessment, Infection, Conjunctivitis	Altered Intercellular Communication	Infections of the conjunctiva cause the blinding disease trachoma, an immuno-pathological disease that is characterised by chronic conjunctival inflammation and fibrosis.	24651768
Orbital Pseudotumor	Altered Intercellular Communication	Orbital inflammation is a potentially blinding and disfiguring disease process that is often treated with systemic corticosteroids and immunosuppression; better treatments are needed.	24652467
Orbital Pseudotumor	Altered Intercellular Communication	To determine whether rituximab, a monoclonal antibody against the B-lymphocyte antigen CD20, is effective in the treatment of refractory orbital inflammation.	24652467
Orbital Pseudotumor	Altered Intercellular Communication	Ten individuals with orbital inflammation refractory to systemic corticosteroids and at least 1 other immunosuppressive agent were enrolled from January 2007 to March 2010.	24652467
Inflammation	Altered Intercellular Communication	Initial responders with recurrent inflammation after week 24 were permitted reinfusion with an additional cycle of 2 open-label 1000-mg rituximab infusions.	24652467
Inflammation, orbit (eye disorders)	Altered Intercellular Communication	The primary outcomes were reduction of inflammation measured with a validated orbital disease grading scale and corticosteroid dose reduction by at least 50%.	24652467
Inflammation	Altered Intercellular Communication	Four patients who were positive responders at the week 24 end point experienced breakthrough inflammation after week 24 and received reinfusions between 24 and 48 weeks.	24652467
Noncommunicable Diseases, Orbital Pseudotumor	Altered Intercellular Communication	Rituximab was safe and effective in 7 of 10 patients with noninfectious orbital disease, although 4 required reinfusion with rituximab to maintain control of orbital inflammation.	24652467
Orbital Pseudotumor	Altered Intercellular Communication	Rituximab should be considered in the treatment of refractory orbital inflammation.	24652467
Facial paralysis, Palsy	Altered Intercellular Communication	Facial nerve palsy results in the loss of facial expression and is most commonly caused by a benign, self-limiting inflammatory condition known as Bell palsy.	24652558
Inflammation	Altered Intercellular Communication	Our data support the role of chronic inflammation in the development of ARMD.	24654791
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Light microscopy showed fibrosis with abundant collagen deposition but no inflammation in all patients.	24655442
Inflammation	Altered Intercellular Communication	A smouldering low-grade inflammation favouring low TGF-b1 concentrations is postulated as the primary pathological process leading to PHSD.	24655442
Inflammation, N-nitrosomorpholine, DGCR2 gene, Neuromyelitis Optica, Demyelinating Diseases	Altered Intercellular Communication	Neuromyelitis optica (NMO) is a serious inflammatory demyelinating disease (IDD), characterized by the inflammation and demyelination of optic nerves and spinal cords, which subsequently leads to the loss of function.	24655566
Fibrosis of pancreas, Pancreatitis, Pancreatic carcinoma, Pancreatitis, Chronic	Altered Intercellular Communication	Patients with chronic painful pancreatitis due to HGP with a high lifetime risk of pancreatic cancer should be considered earlier for TP-IAT before pancreatic inflammation results in a higher degree of pancreatic fibrosis and islet cell function loss.	24655839
Granuloma, Interstitial Fibrosis Assessment	Altered Intercellular Communication	All IGO cases had an epithelioid granulomatous reaction confined to seminiferous tubules, an extensive interstitial lymphoplasmacytic inflammation, 3 of 6 had prominent interstitial fibrosis, and 3 of 6 cases had plasma cells with an IgG4+/IgG+ ratio >40%.	24656095
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Of the 4 UGO cases, most had predominantly interstitial with less intratubular granulomatous inflammation.	24656095
Inflammation, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Myocarditis is defined as inflammation of the myocardium.	24656318
Inflammation, Fever, CTCAE, Hyperimmunoglobulinemia D	Altered Intercellular Communication	HIDS is clinically characterized by recurrent episodes of fever and inflammation.	24656624
Communicable Diseases, Carcinogenesis, Inflammation	Altered Intercellular Communication	Chronic inflammation and infection are major risk factors for gastric carcinogenesis in adults.	24656654
Virilization, CTCAE, Vaginal Hemorrhage, Hyperestrogenism	Altered Intercellular Communication	Only 2 demonstrated hormonal manifestations, with vaginal bleeding due to hyperestrogenism in the 7 month old, and virilization in an 11-year-old female.	24656709
Inflammation, Observation Method - Coagulation, Endotoxemia	Altered Intercellular Communication	In a human endotoxemia model, microparticles expressing procoagulant TF (MP-TF) are released in blood concurrently with markers of inflammation and coagulation.	24657035
Inflammation, Carotid Intima-Media Thickness, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Patients with procoagulant-imbalance detected as ETP-ratio greater or PICI% lower than the median value of controls tended to have a higher risk of metabolic-syndrome, higher intima-media thickness, fibrosis, steatosis or lobular inflammation, all considered clinical manifestations of NAFLD.	24657400
vascular inflammations, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Systemic vascular inflammation in abdominal aortic aneurysm patients: a contrast-enhanced PET/CT study.	24658166
Inflammation, Atherosclerosis, Aortic Aneurysm, Abdominal, APP gene, vascular inflammations	Altered Intercellular Communication	The aim of this paper was to investigate the presence of systemic vascular inflammation and its relationship with risk factors and biomarkers of systemic inflammation related to atherosclerosis in asymptomatic abdominal aortic aneurysm (AAA) patients.	24658166
vascular inflammations	Altered Intercellular Communication	The present findings support the relevance of systemic vascular inflammation in all phases of atherosclerosis-related disorders.	24658166
Inflammation, Acute vascular insufficiency of intestine (disorder)	Altered Intercellular Communication	Moreover they confirm the concept that acute ischemic syndromes might represent the local result of a systemic inflammation rather than the focal involvement of a single arterial lesion.	24658166
ARCN1 gene, Inflammation	Altered Intercellular Communication	Impaired CTLA-4 responses in COPD are associated with systemic inflammation.	24658432
Pain Distress Question, Inflammation, Complex Regional Pain Syndromes, Hyperalgesia	Altered Intercellular Communication	Complex regional pain syndrome (CRPS) is characterized by signs and symptoms of peripheral inflammation, which leads to peripheral neural sensitization associated most frequently (in about 70%) with blunt pressure hyperalgesia.	24658473
Metabolic Diseases, Hypopituitarism	Altered Intercellular Communication	Decreased level of consciousness in neonates may result from different etiologies, including rare metabolic and hormonal disorder due to anterior pituitary insufficiency.	24658993
Hypopituitarism	Altered Intercellular Communication	Given the clinical findings and decreased level of consciousness, hormonal diagnostic tests and brain CT scan were performed for any evidence of hypopituitarism.	24658993
Inflammation, Immune dysregulation	Altered Intercellular Communication	Furthermore, relationship strain with family, friends and spouses was associated with greater levels of emotion dysregulation and chronic inflammation.	24659156
Inflammation	Altered Intercellular Communication	Neutrophils play a key role in the inflammatory responses where movement of neutrophils toward the site of inflammation depends on CD11b/CD18 expression as adhesion molecules on these cells.	24659162
Heart Diseases, Inflammation	Altered Intercellular Communication	Recent studies have shown that neutrophil lymphocyte ratio (NLR) is a strong indicator in determining inflammation in cardiac and non-cardiac diseases.	24659410
Arterial Stiffness, Inflammation	Altered Intercellular Communication	The main outcome measures were arterial stiffness, endothelial function, biomarkers of inflammation and oxidative stress, and cardiometabolic risk factors.	24659610
Neurotoxicity Syndromes	Altered Intercellular Communication	Although its pathogenesis is not fully understood, it is postulated that direct damage of methotrexate to the central nervous system plays a major part and elevated levels of homocysteine and its excitatory amino acid neurotransmitter metabolites (homocysteic acid and cysteine sulfinic acid) could mediate, in part, MTX-associated neurotoxicity.	24659737
Sample Size Calculation, Fibrosis Assessment, Inflammation, Vascular Diseases	Altered Intercellular Communication	RDW in SSc may represent an integrative measure of multiple pathological processes including extensive vasculopathy, fibrosis or ongoing inflammation.	24659752
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Synovial inflammation assessed by ultrasonography correlates with MRI-proven osteitis in patients with rheumatoid arthritis.	24659755
Refractory anemias, Inflammation	Altered Intercellular Communication	The aim of this study was to explore whether assessment of synovial inflammation by ultrasonography correlates with MRI-proven osteitis in patients with RA.	24659755
Granulomatous inflammation	Altered Intercellular Communication	Initial fine needle aspiration cytology (FNAC) of the cervical lymph node was suggestive of granulomatous inflammation; the chest radiograph was normal.	24660565
Granulomatous inflammation, Sarcoidosis, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	This time an excision biopsy of the lymph node was done which revealed discrete, non-caseating, reticulin rich granulomatous inflammation suggestive of sarcoidosis.	24660565
Inflammation	Altered Intercellular Communication	FNAC from this lymph node showed caseating granulomatous inflammation and the stain for acid-fast bacilli was positive.	24660565
Inflammation, Tuberculosis	Altered Intercellular Communication	It was also more often found in the tuberculosis group than in the inflammation group (P < 0.01).	24661424
Pneumonitis, Tuberculosis	Altered Intercellular Communication	It may also help distinguish tuberculosis from other causes of lung inflammation.	24661424
Inflammation	Altered Intercellular Communication	Regular exercise training has been shown to reduce systemic inflammation, but there is limited research directly comparing different types of training.	24662224
Pain Distress Question	Altered Intercellular Communication	These were pain (median rating, 10), loss of joint motion (median rating, 9), work loss (median rating, 7), and joint inflammation/swelling (median rating, 8).	24662554
Inflammation	Altered Intercellular Communication	These radiologic abnormalities occurred in more advanced stages of the otovestibular deterioration, supporting the hypothesis that these lesions might represent the end phase of a low-grade chronic inflammation or protein deposition.	24662630
Meningioma	Altered Intercellular Communication	Somatostatin receptor-positive granulomatous inflammation mimicking as meningioma on simultaneous PET/MRI.	24662657
Necrotizing granulomatous inflammation, Meningioma	Altered Intercellular Communication	We report a case of a somatostatin receptor-positive extra-axial necrotizing granulomatous inflammation mimicking as meningioma on simultaneous Ga DOTATATE PET/MRI.	24662657
Inflammation, Primary malignant neoplasm, Inflammatory disorder	Altered Intercellular Communication	While macrophage migration inhibitory factor (MIF) has been extensively studied in the context of inflammation and inflammatory disorders, less work has been devoted to its involvement in cancer, notably in neoplastic progression.	24663824
Inflammation	Altered Intercellular Communication	Impairment of the ubiquitin-proteasome pathway in RPE alters the expression of inflammation related genes.	24664704
Retinitis	Altered Intercellular Communication	These data suggest that impairment of the UPP in RPE may be one of the causes of retinal inflammation and abnormal functions of monocyte and the complement system during the pathogenesis of age-related macular degeneration.	24664704
Vasculitis, Giant Cell Arteritis	Altered Intercellular Communication	Positron emission tomography assessment of large vessel inflammation in patients with newly diagnosed, biopsy-proven giant cell arteritis: a prospective, case-control study.	24665112
Giant Cell Arteritis, GCA gene	Altered Intercellular Communication	Positron emission tomography (PET) scan is emerging as a promising imaging technique to detect large-vessel inflammation in giant cell arteritis (GCA).	24665112
Sepsis, Inflammation	Altered Intercellular Communication	We investigated PON1 activity in surgical patients with sepsis in relation to oxidative stress status, inflammation, disease severity, and survival.	24665146
Communicable Diseases, Inflammation, Valvular endocarditis	Altered Intercellular Communication	Patients with early infection were more likely to be female, on anticoagulation, and present with localized inflammation, whereas those with late infection were more likely to have CIED erosion or valvular endocarditis.	24665867
Airway structure, Acid reflux	Altered Intercellular Communication	The results support an association between gastroesophageal reflux and upper airway inflammation.	24665868
prostatitis	Altered Intercellular Communication	Patients with prostate inflammation had a statistically significant higher grade of AGA, together with higher PSA.	24665929
prostatitis	Altered Intercellular Communication	A novel finding of our study is that BPH patients with prostate inflammation had a significantly higher grade of AGA together with significantly higher PSA levels.	24665929
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	We have reported that second-generation colon capsule endoscopy (CCE-2) might be feasible for assessing the severity of mucosal inflammation in ulcerative colitis (UC).	24666340
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Assessment of tissue oxygenation of periodontal inflammation in patients with coronary artery diseases using optical spectroscopy.	24666796
Inflammation, Systemic disease	Altered Intercellular Communication	This study supports the hypothesis that optical spectroscopy can determine the periodontal inflammation in patients with certain systemic disorders like CAD.	24666796
Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Prognostic performance of inflammation-based prognostic indices in primary operable non-small cell lung cancer.	24667648
Inflammation, CNS disorder	Altered Intercellular Communication	Whether it is associated with CNS disease or a marker of inflammation requires further investigation.	24668125
Prostate carcinoma	Altered Intercellular Communication	Higher levels of inflammation-associated cytokines correlate with poorer prostate cancer outcomes and may guide strategies to improve prostate cancer therapy.	24668612
Airway structure, Bronchopulmonary Dysplasia	Altered Intercellular Communication	Airway inflammation is involved in the pathogenesis of bronchopulmonary dysplasia (BPD).	24668942
Atherosclerosis, Sepsis, Hypercholesterolemia, Cerebrovascular accident, Chronic heart failure, Hypertension, CTCAE	Altered Intercellular Communication	High ADMA levels have been shown to be related with disorders causing vascular inflammation such as hypertension, hypercholesterolemia, atherosclerosis, chronic heart failure, stroke and sepsis.	24669818
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	In addition, these data might suggest the higher ADMA levels in patients could be due to the perivascular inflammation and vasculitis in CA.	24669818
Inflammation	Altered Intercellular Communication	There was a positive correlation between increased sVCAM-1and reduced time required for walking 10 m. PPS might induce neurological improvement by inhibition of chronic inflammation in the spinal cord, through blocking the adhesion cascade by increasing serum sVCAM-1, in addition to rheological improvement of the microcirculation.	24671717
Inflammation, Erdheim-Chester Disease, Histiocytic syndrome	Altered Intercellular Communication	Erdheim-Chester disease (ECD) is a rare form of histiocytosis characterised by uncontrolled chronic inflammation.	24671772
Inflammation, Colitis	Altered Intercellular Communication	Diversion colitis is the inflammation of the excluded segment of the colon in patients undergoing ostomy.	24672659
Inflammation, ARIH1 wt Allele, Acute kidney injury	Altered Intercellular Communication	Oxidative stress and inflammation during cardiac surgery may be associated with acute renal injury (ARI).	24672814
Inflammation, Heart failure	Altered Intercellular Communication	Impaired resolution of inflammation in human chronic heart failure.	24673112
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	Ductal epithelial expression of Ro52 correlates with inflammation in salivary glands of patients with primary Sjogren's syndrome.	24673429
Psoriasis, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Psoriasis is associated with increased risk of cardiovascular disease (CVD), possibly due to chronic low-grade systemic inflammation.	24673617
Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	The UIP pattern or upper lobe fibrosis is remarkably different from GIP in distribution of hard metal elements, associated interstitial inflammation and fibrosis, and clinical features.	24674995
Inflammation, Aneurysm	Altered Intercellular Communication	Both the fragility of the sinus of Valsalva and the residual inflammation could have caused the patient's aneurysm formation.	24676407
Inflammation, Necrosis	Altered Intercellular Communication	Inflammation as well as angiogenesis may participate in the pathophysiology of brain radiation necrosis.	24676944
Inflammation	Altered Intercellular Communication	Both angiogenesis and inflammation might be caused by the regulation of HIF-1a, which is well known as a transactivator of VEGF and of the CXCL12/CXCR4 chemokine axis.	24676944
Fibrosis Assessment, Hepatitis B, Hepatitis, Chronic	Altered Intercellular Communication	Pathological functions of interleukin-22 in chronic liver inflammation and fibrosis with hepatitis B virus infection by promoting T helper 17 cell recruitment.	24677193
Fibrosis Assessment, Hepatitis, Chronic, Hepatitis	Altered Intercellular Communication	In an HBV transgenic (Tg) mouse model of T-cell-mediated chronic liver inflammation and fibrosis, blockade of IL-22 attenuated hepatic expression of chemokine (C-X-C motif) ligand 10 and chemokine (C-C motif) ligand 20 (CCL20) and subsequently reduced Th17 recruitment and liver inflammation and fibrosis progression.	24677193
Fibrosis Assessment, Hepatitis, Chronic	Altered Intercellular Communication	IL-22 plays a pathological role in exacerbating chronic liver inflammation and fibrosis by recruiting hepatic Th17 cells in HBV-infected patients and HBV Tg mice.	24677193
Inflammation, Disease, Obesity	Altered Intercellular Communication	Obesity is a disorder often accompanied by a heightened state of systemic inflammation and immunoactivation.	24678280
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Subsequently VZV-induced inflammation within the affected cerebral arteries leads to occlusion and stroke.	24678919
Inflammation	Altered Intercellular Communication	Inflammaging, a state of chronic inflammation in the elderly, is now thought to be a key element of the ageing process and contributor to age-related disease.	24679110
Inflammation, Presbycusis	Altered Intercellular Communication	Inflammation is associated with a worsening of presbycusis: evidence from the MRC national study of hearing.	24679110
Inflammation	Altered Intercellular Communication	Inflammaging, a state of chronic inflammation in the elderly, is now thought to be a key element of the ageing process and contributor to age-related disease.	24679110
Inflammation, Fibrosis Assessment, kyphosis, Immobile, Spondylitis	Altered Intercellular Communication	Ankylosing spondylitis is a disease in which inflammation of joints, most often in the axial skeleton, can lead to reactive fibrosis and eventual joint fusion with associated immobility and kyphosis.	24679210
Aortic Valve Insufficiency, Uveitis	Altered Intercellular Communication	The disease often involves extra-articular features, such as uveitis and aortic regurgitation, as well as associated inflammatory conditions of the intestines.	24679210
Inflammation, Mucinous, Neoplasms, Fibrosis Assessment, Bronchioloalveolar Adenocarcinoma	Altered Intercellular Communication	Post-mortem lung biopsies gave a diagnosis of mucinous and non-mucinous bronchiolo-alveolar carcinoma with typical lepidic growth pattern of tumor cells and discrete septal thickening but no fibrosis, inflammation or local invasion.	24680118
Pleurisy	Altered Intercellular Communication	Twenty-two of 86 patients (25.5%) had a possible identifiable cause of pleural inflammation (benign disease).	24681036
Inflammation, Obesity	Altered Intercellular Communication	Obesity is associated with systemic inflammation, alterations in the intestinal microbiome, and decreased epithelial integrity.	24681076
Inflammation, Colorectal Neoplasms, Carcinogenesis	Altered Intercellular Communication	MC has a reduced risk of colorectal neoplasia, suggesting that this model of chronic inflammation plays a protective effect against colorectal carcinogenesis.	24681653
granulomatous uveitis, Nongranulomatous uveitis, Steroid-induced myopathy	Altered Intercellular Communication	Seventy percent of OHT in granulomatous uveitis cases was inflammation-induced, while 76.7% in non-granulomatous uveitis cases was steroid-induced.	24682184
granulomatous uveitis, Pupillary block, Uveitis	Altered Intercellular Communication	OHT in non-granulomatous uveitis was mainly steroid-induced open-angle OHT with some cases of angle-closure OHT caused by pupillary block, while that in granulomatous uveitis was mostly inflammation-induced open-angle OHT with no pupillary block-related angle-closure OHT.	24682184
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Lipocalin-2 (Lcn-2) is expressed in human neutrophils and epithelial cells, particularly in the presence of inflammation or cancer.	24682311
Optic Neuritis	Altered Intercellular Communication	Abnormal nerve inflammation coexists and may play a role in pathogenesis.	24682967
Inflammation, Failure (biologic function)	Altered Intercellular Communication	When the cause of early implant failure was inflammation, the failure rate was significantly higher for implants in the anterior maxilla; implants with poor primary stability, a machined surface, or a length exceeding 15 mm; and implants placed with a reconstructive procedure and two-stage surgery.	24683555
Inflammation, Edema	Altered Intercellular Communication	Nasofibroscopic examination revealed a right arytenoid granuloma with oedema and inflammation, and bilateral arytenoid immobility.	24683823
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The physiological factors underlying the association are complex, and they may relate to melatonin excretion patterns, low-grade inflammation in cancer development process or disruptions in circadian rhythmicity.	24684747
tyramine-deoxysorbitol, Avitaminosis, Erectile dysfunction	Altered Intercellular Communication	To evaluate whether hormonal markers predict erectile dysfunction (ED) and symptoms of T deficiency syndrome (TDS), which are commonly found in the population of infertile men.	24684954
Inflammation, Coronary Lesions Treated	Altered Intercellular Communication	Advanced coronary lesions with lipid cores are associated with adventitial inflammation, but the early inflammatory process in human coronary adventitia is largely unknown.	24685316
Respiratory Distress Syndrome, Adult, Inflammation, Pneumonia, Burn Specimen Source Codes	Altered Intercellular Communication	Smoke inhalation, pneumonia and inflammation process are the major causes of ARDS in burn patients.	24685349
Data types - Address	Altered Intercellular Communication	These findings support the assumption that specific NPS features in AD might be (in)directly related to brain region-specific monoaminergic neurotransmitter alterations.	24685637
Inflammation, Chronic disease	Altered Intercellular Communication	A Mediterranean diet (MD) has been associated with reduced inflammation and mortality for major chronic diseases.	24687087
Dyspnea, Lymphocyte count increased, Bronchiolitis, Interstitial inflammation	Altered Intercellular Communication	A 30-year-old, nonsmoking, female baker was referred for progressive dyspnea on exertion, basal crackles on auscultation, restrictive lung function, decreased diffusing capacity of the lung for carbon monoxide, ground glass hyperdensities with a mosaic pattern on high-resolution CT scan, 25% lymphocytosis by BAL, and cellular chronic bronchiolitis with peribronchiolar interstitial inflammation by lung biopsy specimen.	24687706
Arthritis, Cartilage damage, Gout	Altered Intercellular Communication	Exploring cartilage damage in gout using 3-T MRI: distribution and associations with joint inflammation and tophus deposition.	24687845
Inflammation	Altered Intercellular Communication	If the healing process does not take place within a reasonable timeframe, the possibility of a pathologic process beyond localized infection/inflammation should be suspected.	24687889
Intestinal metaplasia, Acute and chronic inflammation	Altered Intercellular Communication	Severe chronic cardia inflammation increased the presence of cardia intestinal metaplasia 6.2 fold (OR=6.288; p<0.0001).	24689092
Inflammation, Atherosclerosis	Altered Intercellular Communication	A state of chronic inflammation is shared by them all, YKL-40 also being involved in the severity of chronic endothelial inflammation, which today is considered of crucial importance for the development of atherosclerosis.	24689875
Refractory anemias, Inflammation	Altered Intercellular Communication	The importance of apolipoproteins in the development of CVEs, in the context of lipids, haemostatic factors, and inflammation, was evaluated over 18 years in patients with RA.	24689997
Inflammation, Tissue injury, Breast Carcinoma	Altered Intercellular Communication	These findings suggest that urinary ADAM 12 may not correlate directly with the status and stage of breast cancer as previously thought; rather these increases may be a result of tissue injury and inflammation from biopsy and surgical resection.	24690292
Inflammation, Periodontitis	Altered Intercellular Communication	Periodontitis involves periodontal tissue destruction and is associated with chronic inflammation and ageing.	24690593
Inflammation, Pericarditis, CTCAE, Disease	Altered Intercellular Communication	Pericarditis is a common human disease defined by inflammation of the pericardium.	24690743
Inflammation	Altered Intercellular Communication	Our findings suggest that an elevated S100A12 level could play a crucial role in systemic inflammation and may be a promising biomarker for predicting cardiovascular events and perioperative complications in patients with TAD.	24691129
Inflammation, Carotid Intima-Media Thickness	Altered Intercellular Communication	Among those with a CAC score of zero, T-cell activation and systemic inflammation correlated with carotid intima-media thickness and brachial hyperemic velocity, respectively.	24691204
Inflammation, Pancreatic carcinoma	Altered Intercellular Communication	Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression.	24691445
Primary malignant neoplasm, Pancreatitis	Altered Intercellular Communication	Furthermore, evaluation of human pancreatic tissue and cancer cells revealed that Sin3B was decreased in control and PDAC samples, compared with samples from patients with pancreatic inflammation.	24691445
Inflammation	Altered Intercellular Communication	These results indicate that senescence-associated inflammation positively correlates with PDAC progression and suggest that SIN3B has potential as a therapeutic target for inhibiting inflammation-driven tumorigenesis.	24691445
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Complement activation and inflammation have been suggested in the pathogenesis of stroke; mannose-binding lectin (MBL) was found to have roles during the process.	24691546
Inflammation, Blood Clot	Altered Intercellular Communication	As evidence points towards an extensive "cross-talk" between the inflammatory and coagulation cascade, inflammation has been claimed as a possible mechanism through which different risk factors trigger venous thrombus formation.	24691730
Inflammation, Chronic heart failure	Altered Intercellular Communication	Elevated levels of serum sialic acid and high-sensitivity C-reactive protein: markers of systemic inflammation in patients with chronic heart failure.	24693572
Inflammation	Altered Intercellular Communication	Although it has been shown that inflammation occurs in HF, inflammatory markers have yet to be defined.	24693572
Inflammation, Chronic heart failure	Altered Intercellular Communication	Thus, TSA and hs-CRP would appear to be stable markers of systemic inflammation in chronic heart failure.	24693572
Inflammation, Hemorrhage, Gingival Hemorrhage	Altered Intercellular Communication	Both treatment groups experienced significant reductions in number of bleeding sites, gingival bleeding index (GBI), and gingival inflammation (MGI) relative to baseline (P < 0.001).	24693625
Inflammation, Hemorrhage, Obstruction, Meckel Diverticulum	Altered Intercellular Communication	Hemorrhage, obstruction and inflammation are the three main categories of complications resulting from Meckel's diverticulum.	24693872
Refractory anemias, Inflammation, ciliary vesicle	Altered Intercellular Communication	We sought to test the hypothesis that due to increased inflammation, CV disease and risk factors are associated with increased risk of future RA development.	24693947
Inflammation, Ascites	Altered Intercellular Communication	Continuous inflammation and ascites 10 months after the initiation of peritoneal dialysis.	24694494
palladium, Inflammation, Ascites	Altered Intercellular Communication	Based on these findings, in addition to the presence of continuous inflammation and ascites, a diagnosis of pre-encapsulating peritoneal sclerosis was suspected, and the treatment was switched from PD to hemodialysis.	24694494
Intraocular inflammation, Neurosyphilis, Vitelliform-like macular lesions	Altered Intercellular Communication	The patient received standard treatment for neurosyphilis with intravenous penicillin G. Two months later, the intraocular inflammation had resolved, but the resolution of the vitelliform lesions was more gradual.	24695048
Lymphoid neoplasm, Fibrosis Assessment, Liver damage, Cholestasis	Altered Intercellular Communication	INH was stopped, and she received N-acetyl cysteine and Vitamin K. Liver biopsy showed moderate to severe lymphocytic and plasmacytic portal and lobular inflammation, prominent ductal proliferation, moderate cholestasis (predominantly hepatocellular and canalicular), hepatocellular damage, and stage 3 bridging fibrosis.	24695480
Inflammation, Fibrosis Assessment, Liver damage, Cholestasis	Altered Intercellular Communication	Liver biopsy two years later showed mild portal inflammation, predominantly lymphocytitic, mild portal fibrosis without bridging, irregular bile ducts without cholestasis, and no significant hepatocellular damage; overall the later biopsy demonstrated significant improvement.	24695480
Hypophysitis, CTCAE, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Hypophysitis is a chronic inflammation of the pituitary gland of unknown (primary forms) or recognizable (secondary forms) etiology, such as the use of ipilimumab in cancer immunotherapy.	24695685
Inflammation, Parakeratosis	Altered Intercellular Communication	Changes in parakeratosis, inflammation and dermal collagen remodelling were also observed.	24696069
Inflammation, Helicobacter pylori, Stomach Carcinoma, Carcinogenesis	Altered Intercellular Communication	Considerable progress has been made in understanding the roles of Helicobacter pylori in inflammation and gastric cancer; however, far less is known about the roles of enterohepatic Helicobacter species (EHS) in carcinogenesis and their zoonotic or pathogenic potential.	24696515
Inflammation, Intestinal Cancer, Diarrhea	Altered Intercellular Communication	These results suggest that EHS may represent an aetiological agent mediating diarrhoea, chronic inflammation, and possibly intestinal cancer in non-human primates, and may play a role in similar disease syndromes in humans.	24696515
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Interestingly, near to the malformed vessels, a large area of necrosis with granulomatous inflammation was found.	24696743
Chronic meningitis, Inflammation	Altered Intercellular Communication	Chronic meningitis is inflammation of the meninges where signs and symptoms develop and last for at least four weeks without alleviation.	24696988
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation and immune activation have a crucial role in the pathogenesis of cardiovascular diseases.	24697114
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Our results are in line with a role of inflammation in coronary artery disease.	24697114
Presenile dementia, Inflammation	Altered Intercellular Communication	Compared with other studies of younger-old adults, this suggests that the effect of inflammation on dementia may differ in younger-old and the oldest-old individuals.	24697580
Inflammation, HIV Infections	Altered Intercellular Communication	How does monocyte metabolism impact inflammation and aging during chronic HIV infection?	24697644
Inflammation, Thyroid associated opthalmopathies	Altered Intercellular Communication	Six were excluded from further analysis due to relapse of their thyroid eye disease with increased inflammation.	24697978
Inflammation, Hepatocyte, Abnormal degeneration, Necrosis	Altered Intercellular Communication	Histological examination showed that liver cell edema, degeneration, necrosis, and inflammation were significantly relieved at 3, 6, and 12 months after transplantation.	24698673
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome and inflammation were also more common in young CAD patients than in non-CAD patients.	24698677
Inflammation, Edema	Altered Intercellular Communication	The clinically visible grooves and large edematic papillae clustered on the region of the fissures might be caused by the inflammation and edema underneath the epithelium.	24698850
Retinal Pigments, Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation and endoplasmic reticulum stress are attenuated by supplementation with grape polyphenols in human retinal pigmented epithelium cells and in C57BL/6 mice.	24699803
Inflammation, Diabetic Retinopathy	Altered Intercellular Communication	Inflammation and endoplasmic reticulum (ER) stress are common denominators for vision-threatening diseases such as diabetic retinopathy and age-related macular degeneration.	24699803
Inflammatory abnormality of the eye	Altered Intercellular Communication	In this study, we hypothesized that MGPs would also be effective in attenuating ocular inflammation and ER stress.	24699803
Inflammatory abnormality of the eye	Altered Intercellular Communication	Consistently, acute ocular inflammation and leukocyte infiltration were almost completely dampened (>95%) by MGP supplementation (100-200 mg/kg body weight) in C57BL/6 mice.	24699803
Inflammatory abnormality of the eye	Altered Intercellular Communication	Collectively, we have demonstrated that MGP is effective in attenuating ocular inflammation and ER stress.	24699803
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Systemic inflammation in patients with inflammatory joint diseases does not influence statin dose needed to obtain LDL cholesterol goal in cardiovascular prevention.	24699940
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	There is a lipid paradox in rheumatoid arthritis describing that despite low lipids related to systemic inflammation, there is an increased cardiovascular (CV) risk.	24699940
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Our aim was to evaluate if baseline lipid levels or baseline systemic inflammation were associated with the statin dose sufficient to achieve lipid targets in patients with inflammatory joint diseases.	24699940
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Whether the background inflammation in patients with inflammatory joint diseases over time influences the CV risk reduction related to statins is yet unknown.	24699940
Inflammation	Altered Intercellular Communication	Interleukin (IL) 17A is an inflammatory cytokine expressed by Th 17 cells and plays a role in tissue inflammation by inducing release of proinflammatory and neutrophil-mobilizing cytokines.	24699997
Intraocular inflammation, Mass in iris, Pupil	Altered Intercellular Communication	Anterior examination of the right eye revealed a vascularised iris mass causing pupillary distortion, intraocular inflammation and raised intraocular pressure.	24700045
Therapeutic immunosuppression, Inflammation, Cardiovascular Diseases, Immune System Diseases, Infection, Chronic Kidney Diseases	Altered Intercellular Communication	CKD is associated with a complex state of immune dysfunction characterized by immune depression, predisposing patients to infections, and immune activation, resulting in inflammation that associates with higher risk of cardiovascular disease.	24700875
Pain Distress Question, Inflammation	Altered Intercellular Communication	He initially had pain and inflammation and was treated with immobilization for two weeks.	24701775
Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain and inflammation persisted so plain films and MRI were ordered and they showed a lesion of the medial meniscus.	24701775
Intraocular inflammation, Corneal edema	Altered Intercellular Communication	In all cases corneal edema and intraocular inflammation ceased after vitrectomy.	24701817
Intraocular inflammation	Altered Intercellular Communication	Removal of retained intraocular lens fragments suspended the intraocular inflammation and normalized intraocular pressure in all cases.	24701817
Inflammation, Hypoxia	Altered Intercellular Communication	We observed that hypoxia treatment increased oxidative stress, exacerbated inflammation, and aggravated learning defects in aged APP/PS1 mice.	24702189
Inflammation, Colonization, Data types - Address, Exacerbation of cGVHD, Pruritus	Altered Intercellular Communication	The results of the study indicate that the 1-week stand-alone application of an emollient, tailored to target inflammation, pruritus, compromised barrier function and pathogenic bacterial colonization may offer benefit for the improvement of mild to moderately severe localized flares of AD.	24702445
Cataract, Inflammation	Altered Intercellular Communication	Femtosecond laser-induced macular changes and anterior segment inflammation in cataract surgery.	24702572
Airway structure	Altered Intercellular Communication	Airway inflammation correlates negatively with deep inhalation bronchoprotection against direct stimuli like methacholine.	24702886
Airway structure	Altered Intercellular Communication	We hypothesised that deep inhalation bronchoprotection to methacholine would be absent and airway inflammation would be present in individuals with AHR to inhaled mannitol.	24702886
Inflammation, Acute-On-Chronic Liver Failure	Altered Intercellular Communication	Systemic inflammation is associated with increased intrahepatic resistance and mortality in alcohol-related acute-on-chronic liver failure.	24703488
Multiple Organ Failure, Inflammation, Acute-On-Chronic Liver Failure, CRNKL1 wt Allele, Liver Cirrhosis	Altered Intercellular Communication	Acute-on-chronic liver failure (ACLF) is characterized by acute deterioration of cirrhosis, systemic inflammation and multi-organ failure.	24703488
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Inflammation is also key to the pathobiology of portal hypertension.	24703488
Multiple Organ Failure, Inflammation, CRNKL1 wt Allele	Altered Intercellular Communication	The disturbances in systemic and hepatic haemodynamics in alcohol-related ACLF are associated with dysregulated inflammation, multi-organ failure and marked activation of the sympathetic nervous system.	24703488
Data types - Address	Altered Intercellular Communication	Here we demonstrate AD is a proinflammatory modulator and indicate that MMP-independent mechanisms may play a role downstream of AD-induced inflammatory signaling in dysfunctional vascular remodeling.	24703604
Inflammation, Peripheral Arterial Diseases	Altered Intercellular Communication	Gender and racial differences in endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease.	24703977
Bladder Neoplasm, Inflammation, Cystitis, Calculi, Urethral Stenosis	Altered Intercellular Communication	Most had a negative cystoscopy finding, whereas in 67 of 185 (36.2%), the findings included bladder tumors in 18 (27%), hypervascularity in 18 (27%), radiation cystitis in 13 (19.4%), inflammation in 7 (10.4%), urethral stricture in 5 (7.5%), and calculus disease in 6 (8.9%).	24704325
Communicable Diseases, Granulomatous inflammation, Diarrhea, Chronic Active Colitis, Syndrome, Graft-vs-Host Disease	Altered Intercellular Communication	Cord colitis syndrome after umbilical cord blood transplantation (UCBT) involves late-onset diarrhea, absence of infection or GVHD, chronic active colitis, and granulomatous inflammation that responds to antibiotics.	24704386
Inflammation, Metabolic Syndrome X, Atherosclerosis, Diabetes Mellitus, Obesity	Altered Intercellular Communication	Chronic inflammation closely associates with obesity, metabolic syndrome, diabetes mellitus, and atherosclerosis.	24705587
Inflammation, Ulcer	Altered Intercellular Communication	Specifically, we investigated whether nutrition supply or inflammation affects the serum albumin level in 82 patients with pressure ulcers(s) (29 in whom pressure ulcer was present upon admission and 53 in whom pressure ulcer developed after hospital admission).	24705743
Pressure Ulcer, Inflammation	Altered Intercellular Communication	The serum albumin level appears to reflect inflammation, wound healing, and disease severity rather than nutrition supply in patients with pressure ulcer.	24705743
Inflammation	Altered Intercellular Communication	In joints with positive SV, changes in structural alteration did not relate to total SV values, which reflect total exposure to inflammation in an observational period.	24706991
Hepatic, Inflammation	Altered Intercellular Communication	The activity of periportal and lobular inflammation was scored 0 (none or minimal activity) to 4 (severe), and the degree of hepatitic rosette formation and emperipolesis was semiquantatively scored 0-3.	24707143
Inflammation, Hepatitis, FAM126A gene	Altered Intercellular Communication	Study findings are in accordance with the hepatocellular carcinogenic model where IL28B TT genotype, by promoting a persistent chronic hepatitis which leads to both hepatocyte injury and chronic inflammation, could facilitate HCC development.	24707497
Sepsis, Inflammation, Injury of kidney	Altered Intercellular Communication	In vivo EPC administration in sepsis increased plasma IL-10, suppressed lung vascular leakage, attenuated liver and kidney injury, and augmented miR-126 and -125b expression, which regulate endothelial cell function and/or inflammation.	24707934
Acute chest pain	Altered Intercellular Communication	EFN is a benign inflammatory condition frequently overlooked in the ED by physicians and radiologists but is an important factor in the differential diagnosis of patients with acute chest pain.	24707937
anaphylaxis, Chronic inflammation	Altered Intercellular Communication	Our report may provide a potentially effective therapeutic approach for the first time to other LP patients who are experiencing recurrent anaphylaxis and/or chronic inflammation.	24708644
Inflammation, Gout	Altered Intercellular Communication	Gout is characterized by episodes of intense joint inflammation in response to intra-articular monosodium urate monohydrate (MSU) crystals.	24708712
Inflammation, Fever, CTCAE, Hereditary	Altered Intercellular Communication	Hereditary periodic fever syndromes (HPFS) are rare diseases characterised by recurrent, self-limited episodes of fever and localised inflammation, which arise from monogenic defects.	24708999
Perineural spread, Inflammation, Tumor Cell Invasion	Altered Intercellular Communication	Of 239 patients (48%) with nerve invasion, 174 (73%) had perineural invasion, 65 (27%) intraneural invasion, and 37 (15%) perineural inflammation.	24710845
Communicable Diseases, Inflammation	Altered Intercellular Communication	They are related to intestinal energy, motility, and transport and to protective effects against infection and inflammation.	24711120
Inflammation, MS gene	Altered Intercellular Communication	Evaluating microglial activation with TSPO-binding PET ligands provides a unique tool to assess diffuse brain inflammation and perilesional activity in progressive multiple sclerosis in vivo.	24711650
Inflammation	Altered Intercellular Communication	Histology of the muscle showed non-specific inflammation of the external and internal oblique muscles.	24711865
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	As inflammation and oxidative stress were makedly encountered in the etiology, high cholesterol was also defined to provoke atrial fibrillation.	24712763
Inflammation, Fibrosis Assessment, Neoplasms, FAM126A gene	Altered Intercellular Communication	The proportion of CLC was significantly correlated with the degree of fibrosis (P < 0.01) and inflammation (P < 0.01), and inversely correlated with tumour size (P < 0.01) and histological grading of HCC (P < 0.05).	24712771
Deficiency of butyryl-CoA dehydrogenase, Connective Tissue Diseases, Vasculitis, CTCAE	Altered Intercellular Communication	Non-atherosclerotic SCAD is clearly associated with connective tissue disorders, vasculitis, and the peripartum period with its hormonal and haemodynamic changes.	24712892
Inflammation, Cholangitis	Altered Intercellular Communication	Patients with cholangitis may exhibit repeated and chronic inflammation of the biliary tract despite successful medical or surgical treatments.	24713207
Inflammation, Hemolysis (biological function)	Altered Intercellular Communication	Laboratory tests were consistent with haemolysis and inflammation.	24713708
Oculogyric crisis, Floppy infant syndrome, Diarrhea, Disturbance	Altered Intercellular Communication	In view of his infantile-onset hypotonia, oculogyric crises, and protracted diarrhoea, an autonomic disturbance related to neurotransmitters was suspected.	24714172
Refractory anemias, Rheumatoid Arthritis, Rheumatic Fever, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a chronic, autoimmune, systemic and inflammatory rheumatic disease that leads to inflammation of the joints and surrounding tissues.	24714506
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Aged JKAP-knockout mice spontaneously develop inflammation and autoimmunity.	24714587
Inflammation, Atherosclerosis	Altered Intercellular Communication	Systemic inflammation and brachial artery endothelial function in the Multi-Ethnic Study of Atherosclerosis (MESA).	24714919
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Inflammation and endothelial dysfunction have been implicated in the pathogenesis of atherosclerotic vascular disease.	24714919
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Elevated IL-6 levels may reflect a state that promotes vascular inflammation and development of subclinical atherosclerosis independent of traditional cardiovascular risk factors.	24714919
Inflammation	Altered Intercellular Communication	Low bone mineral density in young individuals is associated with greater gingival inflammation and recession.	24715239
Inflammation, Secondary osteoporosis, Gingival Hemorrhage	Altered Intercellular Communication	Significantly higher gingival recession (GR), gingival bleeding time index, and hence gingival inflammation were noted in patients with secondary osteoporosis compared to healthy subjects.	24715239
Inflammation	Altered Intercellular Communication	In conclusion, low BMD in young individuals was associated with greater gingival inflammation and recession when compared to those individuals with normal BMD values.	24715239
Inflammation, Nodular lesions, teratologic	Altered Intercellular Communication	Nodular lesions or masses were the most common anomalies detected during computed tomography scans, but disseminated inflammation and interstitial changes were also seen.	24715630
Inflammation	Altered Intercellular Communication	There is some evidence suggesting a relationship between inflammation and VSA.	24716416
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	We sought to demonstrate the relationship between high-sensitivity c-reactive protein (hs-CRP), a sensitive marker of inflammation, and the asymmetric dimethylarginine (ADMA)-induced endothelial dysfunction pathway in patients with VSA.	24716416
Inflammation	Altered Intercellular Communication	Six hours later, subjects underwent bronchoalveolar lavage (BAL) to quantify markers of alveolar inflammation and cell-specific injury.	24716610
Malignant neoplasm of urinary bladder, Inflammation, Granuloma	Altered Intercellular Communication	Prognostic value of inflammation or granuloma after intravesival BCG in non-muscle-invasive bladder cancer.	24717097
Malignant neoplasm of urinary bladder, Inflammation, Granuloma	Altered Intercellular Communication	To evaluate the prognostic value of inflammation or granuloma after intravesical bacille Calmette-Guerin (BCG) treatment in non-muscle-invasive bladder cancer (NMIBC).	24717097
Granuloma, Inflammation	Altered Intercellular Communication	Granuloma was identified in 60 patients and inflammation in 125 patients.	24717097
Granuloma, Inflammation	Altered Intercellular Communication	The progression-free survival rate was higher in the granuloma and inflammation groups (75 months [95% CI: 71-79] and 82 months [95% CI: 78-86], respectively) compared with the normal histology group (33 months [95% CI: 17-48]; log-rank P < 0.001).	24717097
Inflammation, Granuloma	Altered Intercellular Communication	Inflammation or granuloma in histology samples after intravesical BCG treatment for NMIBC are positive markers of response and their absence increases the risk of recurrence and progression.	24717097
Inflammation, Coronary Artery Disease, Aortic Valve Stenosis	Altered Intercellular Communication	Interleukin-6 receptor (IL-6R) gene Asp358Ala (A>C, rs2228145) polymorphism has been associated with lower circulating inflammation biomarkers in coronary artery disease (CAD), such as C-reactive protein (CRP) or fibrinogen, but its role in the pathogenesis of aortic valve stenosis (AS) remains unknown.	24717336
Airway structure, Pathogenesis	Altered Intercellular Communication	Pathogenesis is poorly understood, but excess neutrophilic airway inflammation is seen.	24717640
Sepsis, Inflammation, Pleural Infection, Pneumonia	Altered Intercellular Communication	However, such hospital caseload-outcome relationship (HCOR) has been seldom addressed in rare medical conditions, such as pleural infection, which is usually associated with pneumonia and may progress to systemic inflammation and severe sepsis.	24717777
Inflammation, Nasal Polyps, Inflammatory disorder	Altered Intercellular Communication	Nasal polyposis (NP) is a chronic inflammatory disease and the waste products of this inflammation are reactive oxygen species composed of free radicals.	24717866
Inflammation, MS4A2 wt Allele	Altered Intercellular Communication	The rural environment seems to protect from atopy, but its relation with nonatopic airway inflammations has been less investigated.	24717869
Nasal Polyps, Acute sinusitis	Altered Intercellular Communication	Nasal polyposis is a chronic inflammation of nasal and paranasal sinuses in the pathogenesis of which adhesion molecules may have a significant role.	24717873
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) mucosal inflammation is characterized by an accumulation of effector-memory T cells, but their immune regulatory potential has not been adequately examined.	24717938
Inflammation, Craniosynostosis, Allergy - Charge Type Reason	Altered Intercellular Communication	A higher percentage of CD4Treg and activated T-helper cells in CRS mucosa suggests increased inflammation in CRS, independent of the presence of allergy, microbial culture results, or eosinophilic mucus.	24717938
Inflammation, Neoplasms	Altered Intercellular Communication	The inflammatory healing process after tumor surgery differs from CRS inflammation and may explain the observed findings.	24717955
Mucous Membrane	Altered Intercellular Communication	In the other cases, the endoscopic findings were mucosal defect (18 %), redness/inflammation (16 %), suspicion for gastric heterotopia (5 %) and scar (3 %).	24718939
Arthralgia, Inflammation, Refractory anemias	Altered Intercellular Communication	Previous imaging studies in the arthralgia phase have shown that inflammation precedes RA development.	24718962
Arthritis	Altered Intercellular Communication	It is unknown which symptoms/characteristics relate to subclinical joint inflammation as measured by MRI.	24718962
Synovitis, Inflammation, Tenosynovitis	Altered Intercellular Communication	Symptoms and signs were related to MRI inflammation (based on MRI scores in symptom-free controls; a sum of synovitis, BME and tenosynovitis scores >=3 was considered positive).	24718962
Inflammation	Altered Intercellular Communication	Patients with MRI inflammation were older and were more frequently positive for anti-citrullinated peptide antibodies than patients without MRI inflammation (p<0.001 and 0.049).	24718962
Inflammation	Altered Intercellular Communication	A combination of symptoms/characteristics incompletely differentiated patients with and without MRI inflammation.	24718962
Autoimmune Diseases, Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The risk of damage by colorectal cancer (CRC) may increase due to autoimmune disease and cryptogenic inflammation.	24719038
Inflammation	Altered Intercellular Communication	This study showed that the IFP has a potential role in the induction of synovial inflammation in patients with severe knee OA.	24719336
Inflammation, Obesity	Altered Intercellular Communication	Efforts to reduce obesity and inflammation in this group may help correct abnormal levels of hsCRP and lipids.	24719979
Crohn Disease, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Serum NGAL levels in Crohn's disease and ulcerative colitis children did not correlate with age, gender, disease activity, and indices of the inflammation.	24720485
Inflammation, Demographics Domain, Chronic Kidney Diseases, Diabetes Mellitus	Altered Intercellular Communication	Inflammation may contribute to the high cardiovascular risk in diabetes mellitus (DM) and chronic kidney disease (CKD).	24720535
Inflammation, Congestive heart failure	Altered Intercellular Communication	Inflammation has been designated as a therapeutic target in CHF.	24720919
Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	This work expands what is known on the non-macrophage functions of CSF-1R and its role in solid tumors, and suggests that CSF-1R signaling may have a critical pathogenic role in a prototypical, inflammation-related cancer such as MPM and therefore may represent a promising target for therapeutic intervention.	24722292
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The effects of stress at work and at home on inflammation and endothelial dysfunction.	24722508
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	This study examined whether stress at work and at home may be related to dysregulation of inflammation and endothelial function, two important contributors to the development of cardiovascular disease.	24722508
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	While lack of findings related to inflammation are somewhat surprising, if replicated in future studies, these findings may suggest that endothelial dysfunction is an important biological mechanism linking stress at work with cardiovascular health outcomes in men.	24722508
Airway structure	Altered Intercellular Communication	The exhaled breath temperature (EBT) has been proven to be the expression of airways inflammation as well as of the increased vascularity.	24722795
Bacteremia, Inflammation, Aortitis	Altered Intercellular Communication	CT and PET scans revealed an aneurysmatic soft tissue inflammation which was interpreted as infectious aortitis in the context of salmonella bacteraemia.	24722933
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Systemic inflammation and increased matrix metalloproteinase (MMP) cause elastin degradation leading to abdominal aortic aneurysm (AAA) expansion.	24726061
melanoma, Lymphoma, Hamartoma, Lesion, Merkel cell carcinoma, Orbital Pseudotumor	Altered Intercellular Communication	The histologic subtype was idiopathic orbital inflammation in 2 lesions, lymphoma in 2, Merkel cell carcinoma in 1, hamartoma in 1 and 1 malignant melanoma.	24726395
Inflammation, Pelvic Pain	Altered Intercellular Communication	Pelvic pain and inflammation were assessed in the presence or absence of PAR2 expression and upon PAR2 neutralization.	24726923
Dental Plaque	Altered Intercellular Communication	Serum lipids associated with inflammation-related PET-FDG uptake in symptomatic carotid plaque.	24727313
Inflammation, Carotid Stenosis	Altered Intercellular Communication	We hypothesized that serum lipids, which experimental data suggest may be key initiators of carotid plaque inflammation, would be associated with plaque inflammation on (18)fluorodeoxyglucose (FDG)-PET in patients with acutely symptomatic carotid stenosis.	24727313
Inflammation, Dental Plaque, Rupture	Altered Intercellular Communication	Serum LDL and total cholesterol were associated with acutely symptomatic carotid plaque FDG uptake, supporting experimental data suggesting lipids may promote plaque inflammation, mediating rupture and clinical events.	24727313
Inflammation	Altered Intercellular Communication	However, the rs12692386 G ADAM17 allele is correlated with a higher expression of ADAM17 mRNA, which may play a role in increasing inflammation in IS patients.	24727681
Sepsis, Inflammation, Pulmonary Edema, CTCAE, Malignant Neoplasms	Altered Intercellular Communication	High-dose interleukin 2 therapy (HDIL-2) is an important protocol for advanced malignancies but is limited by systemic inflammation and pulmonary edema that is indistinguishable from sepsis.	24727870
Inflammation	Altered Intercellular Communication	All patients with acute local or systemic inflammation were excluded.	24728515
Inflammation, Anastomotic Leak	Altered Intercellular Communication	A preexisting low-grade inflammation represented by infiltrates of macrophages and neutrophils is a predictor for increased risk of developing colon anastomotic leakage.	24728515
Sepsis, Brain Injuries, Necrotizing Enterocolitis	Altered Intercellular Communication	IAIPs attenuate brain damage in young and adult subjects, decrease during sepsis and necrotizing enterocolitis in premature infants, and attenuate sepsis-related inflammation in newborn rats.	24728724
ARCN1 gene, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Disease	Altered Intercellular Communication	The association with type 2 diabetes mellitus was greater in patients with COPD respect to general population, and correlated with the increase in BMI and the presence of other comorbidities, suggesting that both diseases may be targets of systemic inflammation.	24728837
Vascular lesions, Arteritis	Altered Intercellular Communication	Since then he has been neurologically asymptomatic and control imaging showed only residual intracranial left VA stenosis, with no signs of temporal artery inflammation or new vascular lesions.	24728901
Communicable Diseases, Inflammation	Altered Intercellular Communication	It can spread via cerebral circulation to the central nervous system as a manifestation of a disseminated infection; particularly in patients with immune suppression, which can result in isolated ring-enhancing lesions and inflammation in the brain.	24730375
Macrovesicular hepatic steatosis, Inflammation, Balloon Dilatation	Altered Intercellular Communication	The livers of DIAR-MSG mice showed macrovesicular steatosis, lobular inflammation with neutrophils, and ballooning degeneration after 29 weeks.	24730643
Fibrosis Assessment, Hepatic inflammation, FAM126A gene	Altered Intercellular Communication	SF level, possibly reflecting the degree of hepatic inflammation and fibrosis, is a negative risk factor for survival and recurrence after percutaneous RFA in HCC patients.	24731153
Cessation of life, Inflammation, Tissue Factor	Altered Intercellular Communication	Under persistent stress, death and proliferation are mutually promoted and form the vicious circle that triggers, maintains, and augments the inflammation and progression of TF.	24731510
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Moreover, the vicious circle may be universal, underlying the development of inflammation and fibrosis in various organs and tissues.	24731510
Inflammation, Hyperphosphatemia, CTCAE, Diabetes Mellitus, Calcification of the aorta, Chronic Kidney Diseases	Altered Intercellular Communication	Hyperphospatemia, chronic inflammation, diabetes, and decreased GFR are associated significantly with the presence of aortic calcification in non-dialysis CKD patients.	24732137
Inflammation, Comorbidity	Altered Intercellular Communication	Longitudinal changes in NT-proBNP are associated with changes in inflammation, nutritional status, age and comorbidity.	24732340
Inflammation	Altered Intercellular Communication	Similarly, greater PA indices were also independently associated with a lower level of inflammatory cytokine z score as an index of overall inflammation.	24732722
Pathogenic organism	Altered Intercellular Communication	Inflammation derived from pathogen infection involves the activation of toll-like receptor (TLR) signaling.	24733511
Inflammation	Altered Intercellular Communication	Understanding the mechanism of AGE-mediated signaling leading to these consequences, like oxidative stress, inflammation, apoptosis, etc.	24733604
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The theory that chronic inflammation leads to cancer is well documented.	24734318
Adult T-Cell Lymphoma/Leukemia, Inappropriate ADH Syndrome	Altered Intercellular Communication	Syndrome of inappropriate antidiuretic hormone secretion associated with adult T-cell leukaemia/lymphoma.	24735057
Airway structure, Asthma	Altered Intercellular Communication	In subjects with moderate asthma who use ICS regularly, inhaled budesonide caused a transient dose-dependent vasoconstriction in the airway, thereby reversing one manifestation of airway inflammation.	24735128
Carcinogenic Chlorinated Hydrocarbon, Hepatic inflammation	Altered Intercellular Communication	CHC patients who underwent liver biopsies were subjected to Scheuer scoring analysis for scope of hepatic inflammation.	24736528
Inflammation	Altered Intercellular Communication	Innate immune responses have a critical role in regulating sight-threatening ocular surface (OcS) inflammation.	24736562
Inflammation, Atherosclerosis	Altered Intercellular Communication	Recent advances in basic science have established that inflammation plays a pivotal role in the pathogenesis of atherosclerosis.	24737117
vascular inflammations, Dental Plaque	Altered Intercellular Communication	Several literature studies experimented this new method to identify vascular inflammation, but few have effectively compared PET/CT results with plaque histological data and no studies had directly compared TBR to SUV.	24737136
Inflammation	Altered Intercellular Communication	TBR max and TBR mean values resulted higher in group A (respectively, 1.42 +- 0.32 and 1.34 +- 0.26) than in group B (respectively, 1.16 +- 0.19 and 1.03 +- 0.20) with a statistically significant differences between the two groups and carotid inflammation (respectively, p < 0.01 and p < 0.001).	24737136
Disease, Polyarteritis Nodosa, Inflammation, Vascular Diseases	Altered Intercellular Communication	Adenosine deaminase 2 (ADA2) deficiency due to CECR1 mutations is a recently defined disorder that involves systemic inflammation and vasculopathy often associated with polyarteritis nodosa.	24737293
Inflammation, Chronic disease	Altered Intercellular Communication	Many chronic diseases are characterised by low-grade systemic inflammation.	24737458
Inflammation	Altered Intercellular Communication	In vitro culture and animal experiments suggest oestrogens are anti-inflammatory and might thereby protect against low-grade systemic inflammation.	24737458
Inflammation, senile, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	In the clinical settings and in animal experiments the research was conducted on effectiveness and safety of treatment the benign prostatic hyperplasia, chronic prostatitis in the stage of active inflammation in elderly and senile patients.	24738261
Inflammation, Genus: Leishmania, Leishmaniasis	Altered Intercellular Communication	Cutaneous leishmaniasis was diagnosed by smear and histology, showing large amounts of leishmania amastigotes in subepidermal histiocytes and extensive lymphocyte and plasma cell inflammation.	24739742
Inflammation, Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation	Altered Intercellular Communication	AB103 is a safe, promising new agent for modulation of inflammation after NSTI.	24740134
ovarian neoplasm, Inflammation	Altered Intercellular Communication	Survival in epithelial ovarian cancer (EOC) is influenced by the host immune response, yet the key genetic determinants of inflammation and immunity that affect prognosis are not known.	24740199
Inflammation, Histology	Altered Intercellular Communication	These associations highlight the potential importance of genes associated with host inflammation and immunity in modulating clinical outcomes in distinct EOC histologies.	24740199
Inflammation, Diverticulitis	Altered Intercellular Communication	Diverticulosis can lead to diverticulitis, a colon condition involving inflammation and other complications.	24740401
Inflammation, Fibromyalgia	Altered Intercellular Communication	The finding of this pattern of altered cytokine milieu not only supports the role of inflammation in FMS but also may lead to more definitive diagnostic tools for clinicians treating FMS.	24741634
Inflammation, Chronic Obstructive Airway Disease, Lung diseases	Altered Intercellular Communication	Chronic obstructive pulmonary disease is a lung disorder characterized by chronic inflammation of the respiratory tract after exposure to pollutants, causing the obstruction of small respiratory tracts and the destruction of lung parenchyma.	24741796
Inflammation, Thrombosis	Altered Intercellular Communication	Evidence suggests that platelets play a significant role in inflammation in addition to their role in thrombosis.	24743560
ARCN1 gene, Inflammation	Altered Intercellular Communication	Systemic inflammation is linked to poor short and long term outcomes in COPD.	24743560
glycation, Inflammation	Altered Intercellular Communication	Dietary intake of advanced glycation end products did not affect endothelial function and inflammation in healthy adults in a randomized controlled trial.	24744309
Deficiency of micronutrients, Inflammation	Altered Intercellular Communication	Micronutrient deficiencies are common in 6- to 8-year-old children of rural Nepal, with prevalence estimates modestly affected by inflammation.	24744314
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The association between inflammation and CKD has been explored in several studies.	24745010
Inflammation, Isthmic spondylolisthesis, Abnormality of the vasculature	Altered Intercellular Communication	Based on previous reports about secondary spinal DAVFs, the abnormal vascular communication likely developed secondary to the microtrauma and inflammation on the left L-4 nerve root sleeve, which was attributable to the isthmic spondylolisthesis.	24745354
Inflammation, Traumatic injury	Altered Intercellular Communication	It is important to bear in mind that a spinal DAVF may develop as a consequence of any sort of trauma or inflammation involving nerve roots.	24745354
Inflammation, Depressed mood, Sleep disturbances	Altered Intercellular Communication	Inflammation, sleep disturbances, and depressed mood among community-dwelling older men.	24745777
Inflammation, Sleep disturbances	Altered Intercellular Communication	We sought to determine if sleep disturbances explain a portion of the putative inflammation - depression association among older adults.	24745777
Depression, CTCAE	Altered Intercellular Communication	We also tested whether inflammation-probable depression associations were moderated by age.	24745777
Inflammation, Hostility	Altered Intercellular Communication	The relation between hostility and concurrent levels of inflammation is sex, age, and measure dependent.	24745780
Inflammation, Hostility	Altered Intercellular Communication	Hostility may be associated with greater systemic inflammation.	24745780
Inflammation, Coronary Artery Disease, Hostility	Altered Intercellular Communication	Main and interactive effects of hostility with sex and/or age were evaluated on markers of inflammation, independently of traditional risk factors for coronary artery disease.	24745780
AVP gene, Panhypopituitarism	Altered Intercellular Communication	Further hormonal work-up revealed panhypopituitarism but no diabetes insipidus.	24746111
Inflammation, Diabetes Mellitus, Cardiovascular Diseases	Altered Intercellular Communication	Insulin resistance (IR) and inflammation have been implicated in pathogenesis of diabetes and cardiovascular disease.	24746438
Inflammation, Coronary Artery Disease, Diabetes Mellitus	Altered Intercellular Communication	Hence, we studied the association of dietary factors with IR and inflammation in known patients with diabetes mellitus and coronary artery disease with the hypothesis that carbohydrate and fat will be positively; and protein, fiber and mineral will be negatively associated with IR and inflammatory markers.	24746438
Hereditary Autoinflammatory Diseases, Fever, CTCAE, Cervical lymphadenitis, Aphthous Stomatitis, Pharyngitis	Altered Intercellular Communication	The periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome is an autoinflammatory disease characterized by regularly recurrent fever episodes due to seemingly unprovoked inflammation.	24746456
Inflammation, Ophthalmoplegia, Myositis, CTCAE 5.0, Pain	Altered Intercellular Communication	Ocular myositis is a rare disorder characterized by inflammation of single or multiple extra-ocular eye muscles presenting with painful diplopia and/or ophthalmoplegia.	24746476
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Nitric oxide (NO), mainly synthesized by inducible nitric oxide synthase (NOS2) in pathological conditions, plays an important role in cytotoxicity, inflammation and fibrosis.	24746566
Inflammation, Cachexia, Neoplasms	Altered Intercellular Communication	Inflammation is an important feature of the malignant phenotype and promotes angiogenesis, tumour invasiveness, metastases, and cachexia.	24746841
Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology, Rupture, Plaque, Atherosclerotic	Altered Intercellular Communication	Acute coronary syndrome (ACS) is caused by destabilization and rupture of atherosclerotic plaque in the coronary artery via mechanisms affecting leukocyte signaling, rolling, adhesion, extravasation and inflammation-promoting factors.	24748045
Inflammation, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	Serum g-glutamyltranspeptidase (GGT) level, which is often elevated in hepatocellular carcinoma (HCC), has now been found to be an oxidative stress marker which correlates with inflammation in the extracellular hepatic microenvironment.	24748164
Pulmonary Emphysema, Inflammation, Respiratory Tract Infections, Osteoporosis	Altered Intercellular Communication	In observational studies vitamin D deficiency has been associated with decreased pulmonary function, presence of emphysema and osteoporosis, upper respiratory tract infections, and systemic inflammation.	24748443
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Soluble TNF receptors are produced at sites of inflammation and are inversely associated with self-reported symptoms (WOMAC) in knee osteoarthritis.	24748490
Weight decreased, Bronchial Hyperreactivity, Pneumonitis, Airway Obstruction	Altered Intercellular Communication	hMPV-infected mice lacking AMs exhibited improved disease in terms of body weight loss, lung inflammation, airway obstruction, and hyperresponsiveness compared with AM-competent mice.	24749674
Communicable Diseases, Inflammation	Altered Intercellular Communication	In contrast, AM depletion in the context of RSV infection was characterized by an increase in viral replication, worsened disease, and inflammation, with increased airway neutrophils and inflammatory dendritic cells.	24749674
Pancreatic carcinoma	Altered Intercellular Communication	Prognostic value of systemic inflammation-based markers in advanced pancreatic cancer.	24750233
Malignant Neoplasms	Altered Intercellular Communication	The prognostic significance of various systemic inflammation-based markers has been explored in different cancers.	24750233
Inflammation, Fever, CTCAE, Acute prostatitis, Dysuria, Suprapubic pain	Altered Intercellular Communication	The present study reports the case of a 67-year-old man who was admitted to our transplant unit 3.5 months post transplantation with fever, dysuria, suprapubic pain, symptoms and signs of acute prostatitis, and elevated markers of inflammation and prostate-specific antigen.	24750300
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Systemic inflammation in patients with chronic obstructive pulmonary disease undergoing percutaneous coronary intervention.	24750361
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Coronary Artery Disease	Altered Intercellular Communication	Systemic inflammation plays an important role in both chronic obstructive pulmonary disease (COPD) and coronary artery disease (CAD).	24750361
Inflammation, Kidney Diseases	Altered Intercellular Communication	Protein-bound uremic toxins, inflammation and oxidative stress: a cross-sectional study in stage 3-4 chronic kidney disease.	24751327
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We undertook this study to investigate the associations between IS and PCS and both inflammation and oxidative stress in the chronic kidney disease (CKD) population.	24751327
Inflammation, Toxic effect	Altered Intercellular Communication	Inflammation and oxidative stress may contribute to the nephro- and cardiovascular toxicities of IS and PCS.	24751327
Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	A CT-guided biopsy of the L1-L2 vertebral bodies showed non-caseating granulomatous inflammation.	24751456
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Systemic inflammation has been implicated as an early marker for subclinical cardiovascular disease; however, findings have been inconsistent in the African-American population.	24751480
Inflammation, Periodontitis	Altered Intercellular Communication	Compared with healthy controls, the score of gingival tissue inflammation was significantly increased in the chronic moderate periodontitis (P=0.013) and chronic severe periodontitis (P<0.0001), and the densities (cells/mm(2)) of tryptase-TIM-3 double-positive MCs were significantly increased in both the chronic moderate (P=0.011) and severe periodontitis groups (P<0.0001).	24751779
Inflammation, Periodontitis	Altered Intercellular Communication	However, compared with the chronic moderate periodontitis group, both the score of gingival tissue inflammation (P=0.012) and the density of tryptase-TIM-3 double-positive MCs (P=0.011) in gingival tissue were significantly increased in the severe periodontitis groups.	24751779
Periodontitis	Altered Intercellular Communication	Significantly increased number of tryptase-TIM-3 double-positive MCs had the similar tendency as the severity of periodontitis inflammation in human chronic periodontitis.	24751779
Hypersensitivity	Altered Intercellular Communication	Mast cells (MCs) are implicated in the pathogenesis of allergic reactions and inflammatory conditions through the release of inflammatory mediators.	24751779
Inflammation, Fibrosis Assessment, Swelling, Thyroid associated opthalmopathies	Altered Intercellular Communication	Graves' orbitopathy (GO) is a disfiguring and sometimes blinding disease, characterised by inflammation and swelling of orbital tissues, with fibrosis and adipogenesis being predominant features.	24751986
Inflammation, Hand	Altered Intercellular Communication	Alterations in the CSF metabolome of HIV patients on ART suggest that persistent inflammation, glial responses, glutamate neurotoxicity, and altered brain waste disposal systems contribute to mechanisms involved in HAND that may be augmented with aging.	24752083
TNF protein, human, Inflammation, Depression, CTCAE	Altered Intercellular Communication	In addition, vascular risk factors, including high body mass index level, presence of inflammation markers (e.g., CRP, TNF-a, Hs-CRP, and IL-6), and lack of physical activity, were associated with depression.	24752391
Tissue damage, Acute inflammation	Altered Intercellular Communication	Deregulated and hyperactive inflammation contributes to tissue damage and parasite persistence.	24752514
Primary malignant neoplasm, Hepatic inflammation, FAM126A gene	Altered Intercellular Communication	These findings broaden the knowledge of hepatic inflammation and cancer initiation/progression, and also provide novel prognostic biomarkers and therapeutic targets for HCC.	24752868
Communicable Diseases, Inflammation	Altered Intercellular Communication	Discogenic back pain can be initiated by tissue disruption, and amplified by inflammation and infection.	24753325
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Polymorphism at the TNF-alpha gene interacts with Mediterranean diet to influence triglyceride metabolism and inflammation status in metabolic syndrome patients: From the CORDIOPREV clinical trial.	24753491
TG gene, Tumor necrosis, Inflammation, ETV3 wt Allele	Altered Intercellular Communication	These results suggest that the rs1800629 at the tumor necrosis factor alpha gene interacts with MedDiet to influence TG metabolism and inflammation status in MetS subjects.	24753491
Seizures, Inflammation	Altered Intercellular Communication	We hypothesized that TBI-induced inflammation likely contributes to seizure development.	24754437
Inflammation, Obesity	Altered Intercellular Communication	This corroborates the concept that complement contributes to the low-grade inflammation associated with obesity.	24754458
Inflammation, Impaired cognition, Osteochondritis Dissecans	Altered Intercellular Communication	Accumulating evidence has indicated that inflammation may act as a potential mechanism underlying post-operative cognitive dysfunction (POCD).	24754551
Inflammation, Heart failure	Altered Intercellular Communication	Various adipokines are reported to be associated with the development of heart failure (HF) through insulin resistance and chronic inflammation.	24755035
Inflammation	Altered Intercellular Communication	Long-term exposures to particulate matter air pollution (PM2.5 and PM10) and high traffic load have been associated with markers of systemic inflammation.	24755038
Inflammation, Atherosclerosis	Altered Intercellular Communication	Our previous in-vivo and in-vitro studies demonstrated that inflammation accelerated the progression of atherosclerosis via the dysregulation of the low-density lipoprotein receptor (LDLr) pathway.	24755105
Inflammation	Altered Intercellular Communication	Confocal microscopy showed that inflammation enhanced the translocation of SCAP escorting SREBP-2 from the endoplasmic reticulum to the Golgi, thereby activating LDLr gene transcription.	24755105
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Inflammation contributed to foam cell formation in the radial arteries of ESRD patients via the dysregulation of the LDLr pathway, which could be modulated by the activation of the mTOR pathway.	24755105
Inflammation, HIV, physiopathological	Altered Intercellular Communication	While inflammation predicts mortality in treated human immunodeficiency virus (HIV) infection, the prognostic significance of gut barrier dysfunction and phenotypic T-cell markers remains unclear.	24755434
Inflammation, Acquired Immunodeficiency Syndrome, HIV Infections	Altered Intercellular Communication	Gut epithelial barrier dysfunction, innate immune activation, inflammation, and coagulation-but not T-cell activation, senescence, and exhaustion-independently predict mortality in individuals with treated HIV infection with a history of AIDS and are viable targets for interventions.	24755434
Specimen Source Codes - Abscess	Altered Intercellular Communication	Autopsy revealed adrenal gland chronic inflammation and abscess.	24755510
Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Inflammation-related genetic variations and survival in patients with advanced non-small cell lung cancer receiving first-line chemotherapy.	24755914
Inflammation	Altered Intercellular Communication	We systematically investigated genetic variants within inflammation pathways as potential prognostic markers for advanced-stage NSCLC patients treated with first-line chemotherapy.	24755914
Inflammation	Altered Intercellular Communication	However, this signal is counteracted in noncirrhotic liver tissue (showing various levels of inflammation) by high availability of interleukin-12 and IFN-g, ultimately leading to complete, full Th1-like Treg differentiation.	24756990
Inflammation, Rheumatoid Arthritis, Rheumatoid Factor	Altered Intercellular Communication	Rheumatoid factor as a potentiator of anti-citrullinated protein antibody-mediated inflammation in rheumatoid arthritis.	24757134
Refractory anemias, Inflammation	Altered Intercellular Communication	The combined presence of ACPAs and IgM-RF mediates increased proinflammatory cytokine production in vitro and is associated with increased systemic inflammation and disease activity in RA.	24757134
Inflammation	Altered Intercellular Communication	The inflammation status of the synovial membrane was characterized according to macroscopic criteria and classified as normal/reactive or inflamed.	24757147
Inflammation, Disorder of tendon	Altered Intercellular Communication	The pathogenetic mechanisms underlying tendinopathy remain unclear, with much debate as to whether inflammation or degradation has the prominent role.	24757284
Inflammation, Cholestasis, pathologic cytolysis	Altered Intercellular Communication	The changes of standard indicators of cytolysis, cholestasis and protein metabolism were on average moderate in group with reliable increase of protein concentration of acute phase of inflammation.	24757856
Airway structure	Altered Intercellular Communication	Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state.	24759206
Airway structure, Respiration Disorders	Altered Intercellular Communication	Thus, age-associated alterations in DC-epithelial interactions contribute to chronic airway inflammation in the elderly, increasing their susceptibility to respiratory diseases.	24759206
Inflammation, Impaired cognition	Altered Intercellular Communication	Studies have suggested CD8 lymphocytes may be a possible marker for inflammation, which is believed to be a contributing factor to neurocognitive impairment.	24759562
Reproductive tract infection, Inflammation	Altered Intercellular Communication	Mycoplasma genitalium infection is associated with microscopic signs of cervical inflammation in liquid cytology specimens.	24759719
Inflammation, Uterine Cervicitis, Etiology aspects, Sexually Transmitted Diseases	Altered Intercellular Communication	In this study, we comparatively assessed inflammation among the common infectious etiologies of cervicitis and assessed the potential value of liquid cytology specimens for predicting STIs.	24759719
Primary malignant neoplasm, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	Hepatocellular carcinoma (HCC) is a classical example of inflammation-linked cancer and is characterized by hypervascularity suggesting rich angiogenesis.	24759835
Inflammation, Neoplasms	Altered Intercellular Communication	Nearly all tumors arose in regions of chronic inflammation and caused luminal narrowing with pre-stenotic dilatation.	24760323
Inflammation	Altered Intercellular Communication	Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling.	24760848
Inflammation, Ulcer	Altered Intercellular Communication	Tissue remission was defined by the absence of ulcer at endoscopy and/or absence of signs of acute inflammation at MRI.	24761690
Inflammatory Bowel Diseases, Inflammation, Venous Thromboembolism, Abnormality of coagulation	Altered Intercellular Communication	Literature on incidence of venous thromboembolism in inflammatory bowel disease (IBD) is reviewed as well as the possible pathogenetic mechanisms of this 'hypercoagulable state': role of acquired risk factors, inflammation, coagulation abnormalities and platelets.	24761694
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	IL-32 was involved in cigarette smoke-induced pulmonary inflammation in COPD.	24761997
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	This study revealed the critical role of IL-32 in pulmonary inflammation of COPD and smoker-associated diseases.	24761997
Inflammation	Altered Intercellular Communication	We hypothesized that genetically increased body mass index (BMI) is associated with telomere length shortening and that low-grade inflammation might contribute through elevated C-reactive protein.	24762112
Colorectal Carcinoma	Altered Intercellular Communication	Polymorphisms of inflammation-related genes and colorectal cancer risk: a population-based case-control study in China.	24762198
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The previous studies found that chronic inflammation related to an increased risk of colorectal cancer (CRC).	24762198
Malignant tumor of colon, Primary malignant neoplasm, Colorectal Carcinoma	Altered Intercellular Communication	Multivariate unconditional logistic regression was used to analyse the association of nine SNPs in inflammation-related genes with the risk of CRC, colon cancer and rectal cancer, respectively.	24762198
Colorectal Carcinoma	Altered Intercellular Communication	However, there is no interaction between inflammation-related genes on CRC risk.	24762198
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Both inflammation and mitochondrial DNA (mtDNA) mutation are thought to play a role in the many human cancers.	24762507
Gastritis	Altered Intercellular Communication	Gastric mucosa inflammation was significantly milder in the T group than that in the P group one year after Hp eradication and this persisted for 10 years.	24762588
Inflammatory disease of mucous membrane, Gastritis, Atrophic	Altered Intercellular Communication	Hp eradication may significantly diminish and help halt progression of gastric mucosal inflammation and delay the development of IM and atrophy gastritis.	24762588
Inflammation, Sore to touch	Altered Intercellular Communication	On examination, inflammation was noted over a bony mass associated with tenderness to palpation of the affected area.	24762849
Keratitis, Ulceration, CTCAE	Altered Intercellular Communication	Corneal inflammation and ulceration could not be controlled after 2 weeks of topical antiinflammation treatment.	24763125
Inflammation, Damage	Altered Intercellular Communication	CXCL13 levels were analysed in relation to cellular, molecular and clinical features of inflammation, lymphocyte activation and joint damage.	24764267
Inflammation	Altered Intercellular Communication	In patients with early disease (<12 months duration), CXCL13 expression correlated significantly with synovial markers of local disease activity and systemic inflammation.	24764267
Inflammation	Altered Intercellular Communication	Accordingly, synovial CXCL13 and the local receptor activator of nuclear factor kB ligand (RANKL)/osteoprotegerin (OPG) ratio significantly co-varied (r = 0.52, P < 0.01), independent of the level of local inflammation.	24764267
Inflammation, Disease	Altered Intercellular Communication	Synovial CXCL13 appears to be a marker of a more severe pattern of RA disease, characterized by increased lymphocyte activation and bone remodelling beyond the level of conventional markers of inflammation.	24764267
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Here, we examined the potential contributions of synovial Btk expression and activation to inflammation in rheumatoid arthritis (RA).	24764451
Inflammation, Metabolic Diseases, Necrosis, Communicable Diseases, Fibrosis Assessment, Fatty degeneration, Autoimmune Chronic Hepatitis, Celiac Disease	Altered Intercellular Communication	The disease was diagnosed if liver biopsy revealed steatosis, inflammation, ballooned hepatocytes, Mallory hyaline, or focal necrosis, varying degrees of fibrosis in the absence of clinical, serological, or histological findings of infectious liver diseases, autoimmune hepatitis, metabolic liver diseases, or celiac disease.	24764670
Inflammation, Thrombosis, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Cardiovascular disease (CVD) results from a combination of abnormalities in lipoprotein metabolism, oxidative stress, chronic inflammation, and susceptibility to thrombosis.	24766787
Inflammation, Heart failure, Coronary Artery Disease	Altered Intercellular Communication	Inflammation and future risk of symptomatic heart failure in patients with stable coronary artery disease.	24766981
Inflammation, Thyroid associated opthalmopathies, Diplopia, Disorder of the optic nerve, Muscle of orbit, Unspecified visual loss, Exophthalmos	Altered Intercellular Communication	The results were compared with clinical severity scores (clinical activity score, VISA (vision loss (optic neuropathy); inflammation; strabismus/motility; appearance/exposure) classification, modified NOSPECS (no signs or symptoms; only signs; soft tissue; proptosis; extraocular muscle; cornea; sight loss) score, Gorman diplopia scale, and European Group of Graves' Orbitopathy Classification).	24767223
Inflammation, Strabismus	Altered Intercellular Communication	Clinical scores indicating inflammation and strabismus in patients with TED were positively correlated with overall and visual function-related QOL (Spearman coefficient 0.21-0.38, p < 0.05).	24767223
Dysmotility, Inflammation	Altered Intercellular Communication	In multivariate analysis, age, soft-tissue inflammation, motility disorder of modified NOSPECS, and motility disorder of VISA classification had positive correlation with overall and function-related QOL.	24767223
Inflammation, Exophthalmos	Altered Intercellular Communication	Sex, soft-tissue inflammation, proptosis of modified NOSPECS, and appearance of VISA classification had correlation with appearance-related QOL.	24767223
Inflammation, Fibrosis Assessment, Cholestasis	Altered Intercellular Communication	Histopathology of a needle graft biopsy performed on POD 28 revealed FCH with extensive portal fibrosis accompanied by mild inflammation, hepatocyte ballooning, and ductular proliferation with cholestasis.	24767401
Respiratory Distress Syndrome, Adult, Inflammation, Lung Injury, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	The acute respiratory distress syndrome (ARDS) is a common, devastating complication of critical illness that is characterized by pulmonary injury and inflammation.	24767549
Inflammation	Altered Intercellular Communication	Increased metabolism in plaques, measured as FDG uptake in PET/CT examination, has been associated with markers of inflammation in histological samples.	24767629
Inflammation, Hypoxia, Dental Plaque	Altered Intercellular Communication	This indicates an association between vascularization and inflammation and/or hypoxia, supporting the use of CEUS as a non-invasive method to detect plaque vulnerability.	24767629
Cholesterolosis, Cholecystitis, Hyperplasia, Xanthogranulomatous inflammation	Altered Intercellular Communication	Histologic findings included chronic (91.1%) or acute (15.4%) cholecystitis, cholesterosis (10.9%), adenomyomatous hyperplasia (2.1%), xanthogranulomatous inflammation (2.02%), and "porcelain" gallbladder (0.2%).	24768494
Inflammation, Pancreatitis	Altered Intercellular Communication	Acute pancreatitis as a result of the hookworms migrating into the ampulla of Vater with chronic inflammation was a very rare complication.	24768664
Inflammation, Liver damage, Chronic disease	Altered Intercellular Communication	Th2-type inflammation under conditions of pre-existing chronic disease is associated with liver damage in patients with avian influenza H7N9 virus.	24769417
Inflammation, Chronic disease	Altered Intercellular Communication	Taken together, our results suggest that Th2-type inflammation in H7N9-infected patients with pre-existing chronic diseases likely contributes to the pathogenesis of H7N9 infection and is linked to poor clinical outcomes.	24769417
PROS1 gene, Psoriasis	Altered Intercellular Communication	The initial telomere size from PsA patients was higher than those with cutaneous psoriasis only (n = 53), possibly due to the inflammatory condition.	24769426
Inflammation, Atherosclerosis	Altered Intercellular Communication	Recent studies have suggested that proprotein convertase subtilisin/kexin type 9 (PCSK9) is associated with atherosclerosis and plays a potential role in inflammation.	24769476
Inflammation	Altered Intercellular Communication	These data demonstrate that the plasma PCSK9 levels are independently associated with the WBCC and its subsets, suggesting a potential interaction between PCSK9 and chronic inflammation in patients with CAD.	24769476
Cystic degeneration, Cardiovascular Diseases	Altered Intercellular Communication	Ascending aortic dilatation (AAD) is a common cardiovascular disease and is associated with aortic wall inflammation and cystic degeneration.	24769814
Inflammation	Altered Intercellular Communication	In patients with AAD, RDW and hs-CRP levels are increased, which may indicate the role of inflammation in the pathogenesis of AAD.	24769814
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation and prolonged QT time: results from the Cardiovascular Disease, Living and Ageing in Halle (CARLA) study.	24770373
Uveomeningoencephalitic Syndrome, Blurred vision, Headache, Inflammation	Altered Intercellular Communication	VKH presents as blurring of vision and eye inflammation, severe headaches, and meningismis.	24770410
Inflammation, Observation Method - Coagulation, Pulmonary Hypertension	Altered Intercellular Communication	Fibrinogen has a crucial role in both inflammation and coagulation, two processes pivotal for the pathogenesis of pulmonary hypertension.	24770447
Seizures, Inflammation, Subarachnoid Hemorrhage	Altered Intercellular Communication	Nonconvulsive seizures in subarachnoid hemorrhage link inflammation and outcome.	24771589
Seizures, Brain Injuries, Inflammation Mediators	Altered Intercellular Communication	Proinflammatory states are common after many brain injuries, and inflammation-mediated changes in blood-brain barrier permeability have been experimentally linked to seizures.	24771589
ACSM3 gene, Inflammation	Altered Intercellular Communication	In-hospital NCSz were independently associated with a proinflammatory state following SAH as reflected in clinical symptoms and serum biomarkers of inflammation.	24771589
ACSM3 gene, Inflammation	Altered Intercellular Communication	Our findings suggest that inflammation following SAH is associated with poor outcome and that this effect is at least in part mediated through in-hospital NCSz.	24771589
Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Atrial fibrillation (AF) is burdened by enhanced systemic inflammation and platelet activation, as documented by increased blood levels of soluble CD40L (sCD40L).	24771985
Inflammation, Thrombosis	Altered Intercellular Communication	Inflammation has been associated with insulin resistance, type 2 diabetes mellitus (T2DM), and atherothrombosis.	24772446
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation and prothrombotic state are present in people with T2DM lacking cardiovascular disease.	24772446
Inflammatory, Inflammation	Altered Intercellular Communication	Patients with pSS were classified accordingly with the grade of inflammatory lesions as I = low-grade (low focus score of 1 or 2), II = intermediate-grade (focus score of 3-6) and III = extensive inflammation in the MSG (high focus score of 12).	24772480
Inflammation, Primary malignant neoplasm, Anemia	Altered Intercellular Communication	Often due to a severe somatic condition of the patient, the presence of perifocal inflammation, anemia, age, it is not possible to perform neoadjuvant chemoradiotherapy for rectal cancer.	24772619
Inflammation, Leukocytosis, Fever, CTCAE, Ulcerative Colitis, Abdominal Pain	Altered Intercellular Communication	With increasing of clinical disease activity in patients with UC as well as CD was marked a significantly increased content of calprotectin in stool samples, which was accompanied by increase of indicators of inflammation acute phase: rising RRF, leukocytosis, an increase of frequency of stool with blood and mucus, fever and abdominal pain.	24772858
Inflammation, Transfusion-Related Acute Lung Injury	Altered Intercellular Communication	Patients with transfusion-related acute lung injury had evidence of more systemic inflammation with increases in circulating neutrophils and a decrease in platelets compared with controls.	24776608
Inflammation, Fatty infiltration	Altered Intercellular Communication	At univariate analysis, the IL28B CC genotype was associated with severe portal inflammation in HCV-1 patients (CC vs. 86% vs. 63%, p = 0.005), severe lobular inflammation in HCV-2 patients (CC vs. 44% vs. 23%, p = 0.03), and less fatty infiltration in HCV-1 patients (CC vs. 72% vs. 51%, p = 0.02).	24776764
Inflammation	Altered Intercellular Communication	At multivariate analysis, the genotype CC remained associated with severe portal inflammation in HCV-1, only (Odds Ratio (OR): 95% Confidence Interval (CI): 3.24 (1.23-8.51)).	24776764
Inflammation, Hepatitis C	Altered Intercellular Communication	IL28B genotype is associated with the histological features of chronic hepatitis C in a HCV genotype dependent manner, with CC genotype being independently associated with severe portal inflammation.	24776764
Communicable Diseases, Inflammation, Unspecified visual loss	Altered Intercellular Communication	Specifically, cerebrospinal fluid leak, visual loss, infection, or unanticipated inflammation were not encountered.	24777260
cervical cancer, Acute and chronic inflammation	Altered Intercellular Communication	No expression was detected in cervical cancer and chronic cervical inflammation.	24777814
Inflammation, Fibrosis Assessment, Calcified (qualifier)	Altered Intercellular Communication	Histology revealed chronic and acute inflammation, thick-walled occluded vessels, fibrosis and characteristic bi-refringent lamellar deposits of globotriaosylceramide and calcifications.	24778057
Inflammation, Asthma, Endothelial dysfunction, Coronary heart disease	Altered Intercellular Communication	[The features of risk factors, systemic inflammation, and endothelial dysfunction in patients with asthma concurrent with coronary heart disease].	24779068
Inflammation, Coronary heart disease, Endothelial dysfunction, Choline Dehydrogenase, Mitochondrial, Asthma	Altered Intercellular Communication	To identify risk factors (RFs), to evaluate the impact of systemic inflammation and endothelial dysfunction on the development of asthma concurrent with coronary heart disease (CHD), and to determine the degree of control of the disease.	24779068
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Advice to follow a low-carbohydrate diet has a favourable impact on low-grade inflammation in type 2 diabetes compared with advice to follow a low-fat diet.	24779961
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation may play an important role in type 2 diabetes.	24779961
Inflammation, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is an aging-related disease, the pathogenesis of which involves chronic inflammation and increased oxidative stress.	24780409
Myocarditis	Altered Intercellular Communication	In the remaining cases, PVB was considered to be a bystander with no or limited association to myocardial inflammation.	24781135
Communicable Diseases, Myocarditis	Altered Intercellular Communication	The detection of PVB in myocardial autopsy samples most likely represents a persistent infection with no or limited association with myocardial inflammation.	24781135
Myocarditis	Altered Intercellular Communication	The forensic investigation of myocardial inflammation demands a thorough examination, including special attention to non-viral causes and requires a multidisciplinary approach.	24781135
Myocarditis	Altered Intercellular Communication	In 28 patients, EMB revealed no myocardial inflammation (NM).	24781421
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is a chronic inflammation of the large intestine.	24781989
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Antibodies to IgG4 hinge can be found in rheumatoid arthritis patients during all stages of disease and may exacerbate chronic antibody-mediated inflammation.	24782178
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	In rheumatoid arthritis (RA), autoantibodies such as anti-citrullinated protein antibodies (ACPAs) develop in response to neoepitopes that are formed under conditions of chronic inflammation.	24782178
Inflammation	Altered Intercellular Communication	Since a significant proportion of ACPAs can be of the IgG4 subclass, the formation of anti-IgG4 hinge antibodies may represent one mechanism of ACPA-mediated inflammation.	24782178
Rheumatoid Arthritis, Inflammation, Pain Distress Question, Fatigue	Altered Intercellular Communication	Subgrouping of patients with rheumatoid arthritis based on pain, fatigue, inflammation, and psychosocial factors.	24782222
Inflammation, Central pain, Pain Distress Question, Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	Among patients with rheumatoid arthritis (RA), pain may be attributed to peripheral inflammation or other causes, such as central pain mechanisms.	24782222
Inflammation, Treatment/Psychosocial Effects, Pain Distress Question, Fatigue	Altered Intercellular Communication	Cluster 1 consisted of 89 individuals with low levels of inflammation, pain, fatigue, and psychosocial distress.	24782222
Inflammation, Treatment/Psychosocial Effects, Pain Distress Question, Fatigue	Altered Intercellular Communication	Cluster 2 consisted of 57 individuals with minimal inflammation but high levels of pain, fatigue, and psychosocial distress.	24782222
Inflammation, Pain Distress Question, Fatigue	Altered Intercellular Communication	Although most patients had low levels of inflammation, pain, and fatigue, 47.3% continued to report having moderate to high levels of pain and fatigue.	24782222
Inflammation, Fatigue, Dyssomnias, Pain Distress Question	Altered Intercellular Communication	Most of these patients had minimal signs of inflammation but high levels of fatigue, pain catastrophizing, and sleep disturbance, indicative of a chronic widespread pain syndrome.	24782222
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	CAP was not influenced by inflammation, fibrosis or aetiology.	24782622
Parkinson Disease	Altered Intercellular Communication	Essential change in Parkinson's disease is the impaired neurotransmission in basal ganglia.	24783912
Inflammation, IL13 gene	Altered Intercellular Communication	Allergic rhinitis is inflammation of the nasal mucosa following exposure to allergens.	24784773
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Social network ties and inflammation in U.S. adults with cancer.	24784985
Inflammation, Loss of facial adipose tissue, Sarcopenia, Anorexia	Altered Intercellular Communication	In some patients, inflammation induces anorexia and fat loss in combination with sarcopenia.	24785098
Inflammation, Sarcopenia	Altered Intercellular Communication	In others, appetite is maintained, despite activation of systemic inflammation, leading to sarcopenia with normal or increased BMI.	24785098
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The high prevalence of cardiovascular diseases and chronic inflammation remains a major cause of morbidity and mortality in haemodialysed patients.	24785111
ARCN1 gene	Altered Intercellular Communication	A possible link between increased metabolic activity of fat tissue and aortic wall inflammation in subjects with COPD.	24785152
ARCN1 gene, Inflammation, Cardiovascular system	Altered Intercellular Communication	Fat tissue, and particularly visceral fat, is known to play a role in low grade systemic inflammation in COPD, and is likely to contribute to the excess cardiovascular comorbidity in COPD.	24785152
Inflammation	Altered Intercellular Communication	The degree of visceral fat metabolic activity is associated with aortic inflammation.	24785152
Acute and chronic inflammation	Altered Intercellular Communication	Studies have also demonstrated pathological changes affecting the middle-ear mucosa associated with chronic sinonasal inflammation.	24785308
Inflammation	Altered Intercellular Communication	It may be related to inflammation of the orbit or paranasal sinuses.	24785747
Inflammation	Altered Intercellular Communication	The reversal of the molecular phenotype with CsA and the associated biomarkers can serve as a reference for the successful modulation of tissue inflammation with specific immune antagonists in future studies, contributing to the understanding of the specific cytokines involved in epidermal pathology.	24786238
Schizophrenia, Impaired cognition, Hyperprolinemia, Schizoaffective Disorder	Altered Intercellular Communication	l-Proline is a neuromodulator at glutamatergic synapses, and peripheral hyperprolinemia has been associated with decreased IQ, cognitive impairment, schizoaffective disorder, and schizophrenia.	24787057
Inflammatory Bowel Diseases, Colorectal Carcinoma, Colitis	Altered Intercellular Communication	Low fecal calprotectin accurately identifies inflammatory bowel disease patients without colonic inflammation in whom colorectal cancer surveillance is most effective.	24788218
Inflammation, Atherosclerosis	Altered Intercellular Communication	Varying correlation between 18F-fluorodeoxyglucose positron emission tomography and dynamic contrast-enhanced MRI in carotid atherosclerosis: implications for plaque inflammation.	24788973
Inflammation	Altered Intercellular Communication	(18)F-fluorodeoxyglucose positron emission tomography and dynamic contrast-enhanced MRI have been proposed to quantitatively assess plaque inflammation by probing macrophages and neovessels, respectively.	24788973
Inflammation	Altered Intercellular Communication	The moderate correlation shown only in symptomatic plaques indicates the presence of acute plaque inflammation with increased metabolic activity and cytokine production by inflammatory cells.	24788973
Inflammation	Altered Intercellular Communication	These results suggest efforts of the immune system to reduce inflammation and suppress an exaggerated Th2 response.	24789687
Inflammation, Edema	Altered Intercellular Communication	The severity of edema and subcutaneous inflammation, which was confirmed using ultrasonography, was significantly influenced by gravity.	24790031
Inflammation, Fibrosis Assessment, Primary Neoplasm	Altered Intercellular Communication	After surgery, the primary tumors were assessed histopathologically for fibrosis and inflammation.	24790431
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Cyclo-oxygenase-2 (COX-2), an inducible enzyme expressed in areas of inflammation, is a target of interest for colorectal cancer therapy.	24791632
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Necrosis	Altered Intercellular Communication	The interleukin (IL)-32/tumor necrosis factor (TNF) a pathway is supposed to play a key role in the amplification of the immune response in chronic obstructive pulmonary disease (COPD) inflammation.	24791863
Granulomatous inflammation, Fibrosis Assessment	Altered Intercellular Communication	A CT-guided biopsy revealed granulomatous inflammation, focal fibrosis and acid-fast bacilli consistent with Mycobacterium tuberculosis (TB).	24792024
Inflammation, Aortic Valve Insufficiency	Altered Intercellular Communication	After a detailed auscultation that unmasked a diastolic cardiac murmur, an acute severe aortic insufficiency was further confirmed by echocardiography, showing inflammation and thickening of the entire aorta wall.	24792026
Gastrointestinal inflammation	Altered Intercellular Communication	Faecal calprotectin is used as a sensitive marker for gastrointestinal mucosal inflammation.	24793248
Inflammatory Bowel Diseases, Inflammation, Impaired	Altered Intercellular Communication	The degree of motility impairment within inflammatory small bowel lesions does not significantly correlate with the extent of the lesion but with the motility measured in prelesionary, non-affected segments, suggesting an interdependent functional aspect of inflammation even in morphologically non-affected small bowel segments.	24794863
Inflammation	Altered Intercellular Communication	Soluble markers of inflammation and coagulation but not T-cell activation predict non-AIDS-defining morbid events during suppressive antiretroviral treatment.	24795473
Inflammation	Altered Intercellular Communication	Ovulation influences an increased in inflammation of epithelial ovarian cells as results of constant exposure of cells to ROS.	24795885
Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	The interaction between brain and systemic inflammation may be responsible for the neurodegenerative disease progression.	24795890
Inflammation, physiopathological, Obesity	Altered Intercellular Communication	Obesity is associated with metabolic dysfunction with sex differences and chronic, low-grade inflammation.We proposed that hepatic expression of immune complement C3 related receptors (C3aR, C5aR, and C5L2) would be associated with pre- or postmenopausal status and metabolic profile in severely obese women.	24796007
Inflammation, Chorioamnionitis	Altered Intercellular Communication	The peripheral Treg pool of preterm infants could be altered by prenatal exposure to inflammation and chorioamnionitis; however, the clinical implications of this finding are not yet understood.	24796788
Inflammation, Neoplasms	Altered Intercellular Communication	Intensity of gadolinium enhancement on MRI is useful in differentiation of intracochlear inflammation from tumor.	24797564
Inflammation, Labyrinth, Neoplasms	Altered Intercellular Communication	Intensity of gadolinium enhancement on MRI is useful in differentiation of inflammation from tumors; normalized T1 postgadolinium intensity ratio greater than 3 is strongly suggestive of intralabyrinthine tumor.	24797564
Gout	Altered Intercellular Communication	An MRI assessment of chronic synovial-based inflammation in gout and its correlation with serum urate levels.	24797771
Gout	Altered Intercellular Communication	The aim of this study was to determine the percentage of patients with inter-critical gout who have chronic synovial-based inflammation as evidenced by synovial pannus on a contrast-enhanced magnetic resonance imaging (MRI) of their most involved joint and determine if the presence and/or severity correlates with their serum urate levels.	24797771
Gout	Altered Intercellular Communication	The majority of patients with inter-critical gout have evidence of chronic synovial-based inflammation.	24797771
Inflammation	Altered Intercellular Communication	The healed phase had subtle histological features, sparse medial inflammation, marked medial attenuation, and chronic adventitial inflammation.	24798167
Inflammation, Traumatic injury, Neoplasms, Skin	Altered Intercellular Communication	Osteoma cutis encompasses a group of cutaneous ossifying disorders, more commonly secondary to trauma, inflammation or neoplasms.	24798356
Inflammatory Bowel Diseases, Inflammation, Colitis	Altered Intercellular Communication	In patients with IBD, histologically normal and inflamed colon were distinguishable with per-class accuracies of 0.83 and 0.89, respectively; histologically normal from inactive inflammation with accuracies of 0.73 and 0.89, respectively; and inactive from active colitis with accuracies of 0.87 and 0.84, respectively.	24798637
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Systemic metabolic signaling in acute and chronic gastrointestinal inflammation of inflammatory bowel diseases.	24799023
Gastrointestinal inflammation	Altered Intercellular Communication	Acute and chronic intestinal inflammation stimulates innate and adaptive immune systems, thereby increasing energy demand of activated immune cells.	24799023
Gastrointestinal inflammation	Altered Intercellular Communication	We wanted to find out how systemic metabolic mediators are affected during intestinal inflammation.	24799023
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Intestinal inflammation was accompanied by elevated systemic inflammatory para-meters such as IL-6 and CRP in UC and CD and, concomitantly, with elevated insulin levels and increased insulin/glucose ratio in patients with UC.	24799023
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	In addition, intestinal inflammation was associated with elevated levels of circulating free fatty acids in UC and CD, indicating an activation of the organism's appeal for energy-rich substrates (energy appeal reaction).	24799023
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	RBP-4 serum levels were also high in acute and chronic intestinal inflammation in UC and CD, which can support insulin resistance.	24799023
Inflammation	Altered Intercellular Communication	The organism's "energy appeal reaction" in response to acute and chronic inflammation provides free energy in the circulation, which is needed by inflammatory cells.	24799023
Inflammation	Altered Intercellular Communication	An interval of at least 3 months after surgery may be needed to decrease the inflammation of the peripancreas region after SAP.	24799280
Pleural Effusion, CTCAE, Inflammation, Fever, CTCAE	Altered Intercellular Communication	A 51-year-old man, who had undergone a TLPG at a referring hospital, was referred for fever, elevated inflammation markers, and pleural effusion on postoperative day 3.	24800528
Inflammation, Anastomotic Leak	Altered Intercellular Communication	A T-tube drainage and wrapping with the intercostal muscle flap is a useful choice of treatment for intrathoracic anastomotic leakage with severe inflammation.	24800528
Inflammation	Altered Intercellular Communication	Acute or chronic inflammation of soft tissue could be revealed pathologically.	24800552
Lichen - organism, Fibrosis Assessment, Alopecia, CTCAE, Perifolliculitis	Altered Intercellular Communication	Lichen planopilaris is a type of primary scarring alopecia that is characterized by perifollicular lymphocytic inflammation and fibrosis.	24800713
Inflammation, Bacterial Infections	Altered Intercellular Communication	Bacterial infection, airway and systemic inflammation and clinical outcomes before and after treatment of AECOPD, a longitudinal and cross-sectional study.	24800883
Communicable Diseases, Chronic Obstructive Airway Disease, Inflammation	Altered Intercellular Communication	Abstract Bacterial infection is a major cause of acute exacerbations of chronic obstructive pulmonary disease (AECOPD), which are associated with significantly increased airway and systemic inflammation.	24800883
ARCN1 gene, Inflammation	Altered Intercellular Communication	We measured the airway and systemic inflammation levels, the COPD assessment test (CAT) score and adverse outcomes between patients with and without potentially pathogenic microorganisms (PPM).	24800883
Inflammation	Altered Intercellular Communication	Our data suggest uncultivated bacteria and/or virus might also play important roles in causing inflammation and AECOPD.	24800883
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Chronic inflammation is a well-known risk factor for type 2 diabetes mellitus (T2DM).	24800930
Inflammation, Chronic heart failure	Altered Intercellular Communication	Immunosenescence and inflammation characterize chronic heart failure patients with more advanced disease.	24801091
Inflammation, Congestive heart failure	Altered Intercellular Communication	We hypothesized that patients with CHF may develop immunosenescence due to inflammation and that this may be associated with a worse stage of the disease.	24801091
Inflammation, Virus Diseases, Bacterial Infections, Malignant Head and Neck Neoplasm	Altered Intercellular Communication	The main risk factor for head and neck cancer is consumption of tobacco and alcohol as well as viral infection and bacterial infection by stimulation of chronic local inflammation.	24802266
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Fucosylation is an oligosaccharide modification associated with cancer and inflammation, which is catalyzed by fucosyltransferases.	24802742
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	The systemic chronic inflammation has been postulated to bridge the increased risk of cardiovascular disease and T2D.	24803740
Inflammation	Altered Intercellular Communication	Furthermore, the calprotectin levels and histological grading of both peri- and intra-tumoral inflammation was not correlated.	24803811
Vascular Diseases, Inflammation, diabetic	Altered Intercellular Communication	Relation of asymmetric dimethylarginine levels to macrovascular disease and inflammation markers in type 2 diabetic patients.	24804267
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	We aimed to determine the relation of asymmetric dimethyl arginine (ADMA) levels to atherosclerotic vascular disease and inflammation markers in type 2 diabetes.	24804267
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) has been associated with increased local inflammation in the affected brain regions, and in some studies also with elevated levels of proinflammatory cytokines in peripheral blood.	24804776
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Inflammation may play an important role in the pathogenesis of HFpEF because of its significant contribution to myocardial fibrosis.	24806206
Neurodegenerative Disorders, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Correlations between inflammation, coagulation activation and neurodegenerative disorders are here supported by the observed variations in plasma levels of markers of coagulation activation and endothelial dysfunction.	24806325
Inflammation, Abdomen, Renal mass	Altered Intercellular Communication	Abdominal and pelvic MRI revealed periaortic inflammation and a left renal mass, which were F-FDG avid on PET/CT.	24806606
Inflammation	Altered Intercellular Communication	Epidural biopsy showed chronic inflammation and scattered but not abnormal IgG4-positive cells, possibly related to posttreatment changes.	24806606
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Clusterin affects inflammation, immune responses, and amyloid clearance, which in turn may result in neurodegeneration.	24806679
Lacrimal gland cyst, Inflammation	Altered Intercellular Communication	Nine cases showed lacrimal ductal cysts with varying periductal inflammation, and the contents were pinkish, amorphous materials in 7 cases.	24807540
Inflammation	Altered Intercellular Communication	Inflammatory lesions of the lateral canthal subconjunctival area all originated from lacrimal gland ductules, showing a variable histopathologic spectrum of inflammation and cyst formation.	24807540
Inflammation, Osteopenia, Dysbiosis	Altered Intercellular Communication	In mice, C3 was required for maximal periodontal inflammation and bone loss, and for the sustenance of the dysbiotic microbiota.	24808362
Inflammation, Eye pain, Tuberculosis, Pulmonary	Altered Intercellular Communication	Complications that include visual acuity decline, prolonged anterior chamber inflammation, phthisis bulbi, scleral thinning and ocular pain were noted.	24811050
Inflammation	Altered Intercellular Communication	In this report, we propose eosinophilic inflammation as the precipitant for an aberrant conduction pathway.	24811559
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Bacteria play a role in the onset and perpetuation of intestinal inflammation in IBD.	24811995
Refractory anemias, Inflammation	Altered Intercellular Communication	To examine the relationship between inflammation and FoxO expression in RA, and to analyse the mechanisms and biological consequences of FoxO regulation in RA fibroblast-like synoviocytes (FLS).	24812285
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Abdominal aortic aneurysm (AAA) is characterized as a progressive dilation and degradation of the aortic wall, associated with activation of matrix metalloproteinases (MMPs) and inflammation.	24812324
APP gene, Inflammation	Altered Intercellular Communication	Our results demonstrate that angiotensin II-sensitive miR-712 and its human homolog miR-205 downregulate TIMP3 and RECK, which in turn stimulate aortic MMP activity and inflammation, leading to AAA development.	24812324
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes.	24812430
Inflammation, VWF wt Allele, Gingival Hemorrhage	Altered Intercellular Communication	Gingival bleeding in VWD patients (VWD) may be triggered by gingival inflammation and not a genuine symptom.	24814158
Sepsis, Inflammation	Altered Intercellular Communication	However, some questions remain unanswered, such as whether there is an association between plasma PAI-1 levels and sepsis severity and mortality, and inflammation state during the first week.	24814968
Inflammation, septic	Altered Intercellular Communication	The most interesting findings of our study, to our knowledge the largest series reporting PAI-1 levels during follow-up in septic patients, were that plasma PAI-1 levels during the first week were associated with inflammation, severity and mortality.	24814968
Inflammation	Altered Intercellular Communication	The predictors of interest for the ICU patients might be considerably different than those of the general population and other subgroups with systemic inflammation possibly having a pivotal role.	24814972
Inflammation	Altered Intercellular Communication	Histological inflammation improved after 1 year, (median HAI: 10 vs. 7, P = 0.01) with persistence in 4/5 patients at 3 years (median HAI: 7.5).	24815494
HTLV-I Infections, Inflammation	Altered Intercellular Communication	Also bitemporal lesions can be the consequence of intense and diffuse inflammation associated with HTLV-1 infection.	24815740
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	The cause of ALS is unknown, but inflammation may play a role.	24816788
Airway structure, ARCN1 gene	Altered Intercellular Communication	Exhaled nitric oxide predicts eosinophilic airway inflammation in COPD.	24816967
ARCN1 gene, Chronic Obstructive Airway Disease, Asthma, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) with eosinophilic airway inflammation may represent a unique phenotype, possibly with shared features of COPD and asthma.	24816967
ARCN1 gene, Airway structure	Altered Intercellular Communication	eNO is a good marker to identify COPD patients with eosinophilic airway inflammation.	24816967
Inflammation, Fracture	Altered Intercellular Communication	High levels of neopterin were associated with increased hip fracture risk, as were some of the kynurenines, suggesting a role of IFN-g-mediated inflammation in the processes leading to hip fracture.	24817202
Inflammation, Fracture, Osteopenia	Altered Intercellular Communication	Low-grade systemic inflammation has been associated with bone loss and risk of fractures.	24817202
Inflammation, Fracture	Altered Intercellular Communication	Risk of hip fracture was investigated in relation to markers of inflammation and metabolites in the kynurenine pathway (kynurenines).	24817202
Inflammation	Altered Intercellular Communication	A biopsy of the area revealed nonspecific, active, chronic inflammation.	24817241
Granulomatosis, Congenital Abnormality, Unknown (origin) (qualifier value), Infection, Granulomatosis with polyangiitis, polychondritis, Leprosy, Traumatic injury, Syphilis, Systemic Vasculitis	Altered Intercellular Communication	Saddle-nose deformity can occur as a result of trauma to the nose, but it has also been well described in the setting of infections such as leprosy and syphilis and idiopathic inflammatory conditions such as granulomatosis with polyangiitis (formerly known as Wegener granulomatosis) and relapsing polychondritis.	24817241
Peritonitis, Lymphadenitis, Acute and chronic inflammation, Malignant Neoplasms, Serositis	Altered Intercellular Communication	They included malignant tumors (39 cases), tuberculous peritonitis (28 cases), chronic hepatic inflammation (3 cases), necrotizing lymphadenitis (1 case), and eosinophilic serositis of the small intestine (1 case).	24818547
Orbital Pseudotumor	Altered Intercellular Communication	There was no evidence of orbital inflammation on history or ocular examination.	24819206
Communicable Diseases	Altered Intercellular Communication	Contribution of intestinal barrier damage, microbial translocation and HIV-1 infection status to an inflammaging signature.	24819230
Inflammation, HIV-1 Infection Pathway	Altered Intercellular Communication	Systemic inflammation is a characteristic of both HIV-1 infection and aging ("inflammaging").	24819230
HIV Antigens	Altered Intercellular Communication	Intestinal epithelial barrier damage (IEBD) and microbial translocation (MT) contribute to HIV-associated inflammation, but their impact on inflammaging remains unclear.	24819230
Inflammation, HIV-1 Infection Pathway	Altered Intercellular Communication	Systemic inflammation is a characteristic of both HIV-1 infection and aging ("inflammaging").	24819230
HIV Antigens	Altered Intercellular Communication	Intestinal epithelial barrier damage (IEBD) and microbial translocation (MT) contribute to HIV-associated inflammation, but their impact on inflammaging remains unclear.	24819230
Inflammation	Altered Intercellular Communication	We describe a novel IP that incorporates biomarkers of IEBD, MT, immune activation as well as inflammation.	24819230
Communicable Diseases, Inflammation	Altered Intercellular Communication	Radiographs revealed osseointegration and stable periimplant marginal bone level with no signs of infection or inflammation.	24819533
Inflammation, Primary malignant neoplasm, Cardiovascular Diseases	Altered Intercellular Communication	To determine whether resveratrol levels achieved with diet are associated with inflammation, cancer, cardiovascular disease, and mortality in humans.	24819981
Inflammation, Tumor necrosis, Cardiovascular Diseases	Altered Intercellular Communication	Secondary outcomes were markers of inflammation (serum C-reactive protein [CRP], interleukin [IL]-6, IL-1b, and tumor necrosis factor [TNF]) and prevalent and incident cancer and cardiovascular disease.	24819981
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Relationship between b-Secretase, inflammation and core cerebrospinal fluid biomarkers for Alzheimer's disease.	24820015
Inflammation, Impaired cognition, Trauma, Nervous System, Presenile dementia, "Alzheimers Disease", Anomia, Frontotemporal dementia	Altered Intercellular Communication	We measured markers of amyloid-b protein precursor (AbPP) processing (Ab42, sAbPPb, b-secretase activity), neuronal damage (total tau, p-tau), and inflammation (YKL-40) in CSF from 194 participants with the following diagnoses: subjective cognitive impairment or non-amnestic mild cognitive impairment (na-SCI, n = 44), amnestic mild cognitive impairment (aMCI, n = 45), dementia of the Alzheimer type (DAT, n = 59), frontotemporal dementia (FTD, n = 22), and 24 cognitively normal controls.	24820015
Inflammation, Data types - Address, Frontotemporal dementia	Altered Intercellular Communication	This suggests that inflammation is a common feature in AD and FTD.	24820015
Amyotrophic Lateral Sclerosis	Altered Intercellular Communication	These findings suggest that EPO may be a potential therapeutic candidate having ability to modulate immune-inflammation in ALS.	24820540
Inflammation, Sarcoidosis	Altered Intercellular Communication	Tartrate-resistant acid phosphatase 5a in sarcoidosis: further evidence for a novel macrophage biomarker in chronic inflammation.	24820632
Inflammation, Sarcoidosis	Altered Intercellular Communication	These findings further support our hypothesis that serum TRACP5a is derived from systemic inflammatory MPh and thereby may be a biomarker of inflammation for sarcoidosis and also reflect its disease activity.	24820632
Inflammation, Ascites	Altered Intercellular Communication	A diagnostic laparoscopy with multiple diagnostic biopsies was carried out, but no macroscopic cause of the ascites was found; histopathological examination showed minimal aspects of diffuse and non-specific chronic inflammation.	24820919
Heart Diseases, Communicable Diseases, Inflammation, Atherosclerosis	Altered Intercellular Communication	Evidence suggests that the inflammation caused by infection is associated with the development of atherosclerosis and heart disease.	24820983
Degenerative polyarthritis, Pain Distress Question, Inflammation	Altered Intercellular Communication	Knee pain and inflammation in the infrapatellar fat pad estimated by conventional and dynamic contrast-enhanced magnetic resonance imaging in obese patients with osteoarthritis: a cross-sectional study.	24821663
Inflammation, Knee pain, Osteoarthritis, Knee	Altered Intercellular Communication	To investigate the association between knee pain and signs of inflammation in the infrapatellar fat pad (IPFP) in obese patients with knee osteoarthritis (KOA).	24821663
Pain Distress Question	Altered Intercellular Communication	The bivariate association between KOOS pain and the DCE-MRI perfusion variable "Inflammation" showed a statistically significant correlation (r = -0.42, P < 0.0001).	24821663
Inflammation, Pain Distress Question	Altered Intercellular Communication	Perfusion variables on DCE-MRI reflecting the severity of inflammation in the IPFP and MOAKS Hoffa-synovitis were associated with the severity of pain in KOA.	24821663
Inflammation, Pain Distress Question	Altered Intercellular Communication	These results suggest that severe inflammation in the IPFP is associated with severe pain in KOA and that DCE-MRI is a promising method to study the impact of inflammation in KOA.	24821663
Liver carcinoma, Neoplasms	Altered Intercellular Communication	Comparison of inflammation-based prognostic scores as predictors of tumor recurrence in patients with hepatocellular carcinoma after curative resection.	24823966
FAM126A gene	Altered Intercellular Communication	Preoperative NLR is an independent predictor of RFS in patients with HCC after curative hepatectomy, and is superior to the other inflammation-based prognostic scores.	24823966
Inflammation, Overweight	Altered Intercellular Communication	Prevalence of tissue iron deficiency (sTfR >113.3 nmol/l; 30.6 vs 12.5%; P=0.002) and chronic inflammation (AGP >25 mmol/l; 19 vs 10%; P=0.025) were higher in overweight than in normal-weight children.	24824017
Overweight	Altered Intercellular Communication	The role of adiposity-related inflammation in tissue iron deficiency should be considered even when the prevalence of overweight is relatively low.	24824017
Liver parenchyma, Inflammation, Hepatitis B, Complete atrioventricular block, Hepatitis B, Chronic	Altered Intercellular Communication	To investigate the relationship between the expression of hepatitis B virus (HBV) core antigen and viral replication and liver tissue inflammation damage in chronic hepatitis B (CHB) patients, and to analyze the relationship of core antigen expression differences with clinical and pathological features in e antigen-negative and e antigen-positive CHB patients.	24824119
Inflammation, Fibrosis Assessment, Complete atrioventricular block	Altered Intercellular Communication	Also for the e antigen-positive CHB patients, the HBV DNA titer was positively correlated with the rank level of pulp karyotype in core antigen expression (r = 0.589, P = 0.003) but negatively correlated with lobular inflammation, interface inflammation, and fibrosis level (r = -0.552, P = 0.000; r = -0.381, P = 0.008; r = -0.555, P = 0.000); in addition, the level of peripheral blood lymphocytes was negatively correlated with lobular inflammation and fibrosis level (r = -0.361, P = 0.012; r = -0.356, P = 0.013).	24824119
ARCN1 gene, Airway structure, Chronic Obstructive Airway Disease, Lung Diseases, Obstructive, Asthma	Altered Intercellular Communication	Catalase (CAT) is a part of the active antioxidant defense system and has been studied with regard to its association with asthma and chronic obstructive pulmonary disease (COPD), which are heterogeneous obstructive pulmonary diseases characterized by chronic airway inflammation.	24824229
Airway structure	Altered Intercellular Communication	Asthma is characterized by chronic airway inflammation and remodeling.	24824230
Eosinophilic inflammation	Altered Intercellular Communication	Levels of serum high-sensitivity C-reactive protein (hs-CRP) reflect airway eosinophilic inflammation.	24824230
ARCN1 gene, Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Inflammation and oxidative stress play an essential role in the pathogenesis of chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD).	24824617
ARCN1 gene, Inflammation	Altered Intercellular Communication	The echocardiographic parameters of cardiac function correlate with the markers of inflammation in patients with COPD, which emphasizes the inflammatory background of CVD.	24824617
Inflammatory Bowel Diseases, Inflammation, hepcidin, Anemia	Altered Intercellular Communication	Hepcidin, a key mediator in this anemia, is up-regulated by high iron levels and inflammation, and serum levels are elevated in IBD.	24825446
Inflammation, Carcinogenesis, Disease, Hyperuricemia	Altered Intercellular Communication	Inflammation and hyperuricaemia, which are the major characteristics of gout disease, are thought to be associated with carcinogenesis and anti-carcinogenesis, respectively.	24825466
Sinusitis, Vasculitis, CTCAE	Altered Intercellular Communication	This case highlights the spectrum of vasculitic conditions that may be associated with cavernous sinus inflammation.	24827146
Inflammation, Critical Illness	Altered Intercellular Communication	Our results suggest that in nontrauma critically ill patients, acute alcohol exposure diminishes inflammation and increases numbers of circulating B and T lymphocytes.	24827394
Inflammation, polyps	Altered Intercellular Communication	We speculate that the compaction of the fecal mass in the appendix triggered mucosal inflammation, resulting in the formation of the polyp, which concealed both the feces and appendiceal orifice.	24827483
Inflammation, Arthritis, Psoriatic, atherosclerotic	Altered Intercellular Communication	Increased burden of inflammation over time is associated with the extent of atherosclerotic plaques in patients with psoriatic arthritis.	24827532
PROS1 gene, Inflammation, Arthritis, Psoriatic, Atherosclerosis	Altered Intercellular Communication	To investigate whether a higher burden of inflammation is associated with more severe atherosclerosis in patients with psoriatic arthritis (PsA).	24827532
Inflammation, Atherosclerosis	Altered Intercellular Communication	The association between inflammation over time and atherosclerosis was assessed by regression models adjusted for age, sex and cardiovascular risk factors.	24827532
Inflammation, Atherosclerosis	Altered Intercellular Communication	Exposure to an increased burden of inflammation is associated with more severe atherosclerosis in patients with PsA.	24827532
Inflammation, Tooth Loss, Obesity	Altered Intercellular Communication	Sex Differences of Tooth Loss and Obesity on Systemic Markers of Inflammation.	24828384
Inflammation, Periodontitis, Tooth Loss, Obesity	Altered Intercellular Communication	Sex-specific differences in the incidence of periodontitis and tooth loss may be related to different phenotypes of obesity and their associations with low-grade inflammation.	24828384
Inflammation, Electrocardiogram: myocardial infarction (finding), Occlusive vascular disease, Cerebrovascular accident	Altered Intercellular Communication	Inflammation plays a key role in the pathogenesis of vascular occlusive diseases, such as myocardial infarction and stroke.	24829443
Inflammation, Occlusive vascular disease	Altered Intercellular Communication	We hypothesized that the inflammation induced by surgery itself augments vascular occlusive disease.	24829443
Inflammation, Hypoperfusion	Altered Intercellular Communication	Furthermore, postoperative CRP elevation was associated with intraoperative parameters reflecting hypoperfusion and inflammation.	24829443
Inflammation	Altered Intercellular Communication	In conclusion, eosinophils triggered a more severe form of inflammation in CRSwNP compared with non-eosinophilic inflammatory cells.	24830325
Degenerative polyarthritis, Cartilage destruction	Altered Intercellular Communication	Supplementation with exogenous H2S sources can regulate the expression of relevant genes in OA pathogenesis and progression, counteracting IL1b pro-inflammatory signals that lead to cartilage destruction in part by reducing NFkB activation.	24831018
Orbital Pseudotumor	Altered Intercellular Communication	He first presented with right orbital inflammation that did not improve despite antibiotic treatment.	24831308
Inflammation	Altered Intercellular Communication	Computer tomography (CT) of the orbits showed a soft tissue mass along the roof of the orbit, which was biopsied, revealing acute on chronic inflammation.	24831308
Orbital Pseudotumor	Altered Intercellular Communication	There was complete resolution of his orbital inflammation within 2 weeks of initiating systemic steroid treatment.	24831308
Orbital Pseudotumor	Altered Intercellular Communication	He subsequently developed recurrent bouts of left orbital inflammation.	24831308
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Final histopathologic diagnosis of the lesion was confirmed as chronic granulomatous inflammation, combined with the neurosyphilis history, spinal dural syphilis granuloma was finally diagnosed.	24831378
Lung hyperinflation, Airway Obstruction, Hypoxemia, Inflammation	Altered Intercellular Communication	Airway obstruction, lung hyperinflation, markers of systemic inflammation and cardiovascular health, exacerbation frequency, smoking habits, and body composition were tested as possible predictors of PaO2 and first episode of hypoxemia.	24831555
Inflammation	Altered Intercellular Communication	Five patients had magnetic resonance imaging showing asymmetry of the vulva with no enhanced signaling associated with inflammation.	24832171
Inflammation, Weight decreased	Altered Intercellular Communication	Exercise training reduces systemic inflammation in weight-stable people, but concurrent diet-induced body weight loss is not well studied.	24832193
Inflammation, Overweight	Altered Intercellular Communication	These findings indicate that resistance training is an effective means for older, overweight adults to reduce systemic inflammation.	24832193
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Evaluating the role of inflammation in chronic airways disease: the ERICA study.	24832197
Pain Distress Question, Sinusitis	Altered Intercellular Communication	The authors present here a 56-year-old man who complained of isolated OD pain with no evidence of cerebral or sinus inflammation on imaging.	24833448
Inflammation, Thrombosis	Altered Intercellular Communication	Von Willebrand factor (VWF), a key player in hemostasis and thrombosis, is released from endothelial cells during inflammation.	24833640
Inflammation, Dental Plaque	Altered Intercellular Communication	Positron emission tomography employing [(18)F]fluorodeoxyglucose can visualize plaque inflammation; however, the question remains whether this is specific for plaque vulnerability.	24834996
Inflammation, Autoimmune Pancreatitis, Fibrosis Assessment	Altered Intercellular Communication	Autoimmune pancreatitis is a benign process characterized by inflammation and fibrosis.	24835039
Inflammation, Thyroid associated opthalmopathies, Strabismus	Altered Intercellular Communication	Thyroid ophthalmopathy activity was defined using the VISA (vision, inflammation, strabismus, and appearance/exposure) classification for TED.	24835350
Inflammation, Fever, CTCAE, Inflammatory disorder	Altered Intercellular Communication	Autoinflammatory diseases represent an expanding spectrum of genetic and non-genetic inflammatory diseases characterized by recurrent episodes of fever and systemic inflammation, affecting joints, skin and serosal surfaces.	24835548
Inflammatory abnormality of the eye	Altered Intercellular Communication	Severe ocular surface inflammation with fibrovascular tissue surrounded the PED in all 10 eyes.	24835597
Vitreous inflammatory cells	Altered Intercellular Communication	Objective measurement of vitreous inflammation using optical coherence tomography.	24835759
Vitreoretinal Area, Intraocular inflammation, Panuveitis, Uveitis, Vitreous haze	Altered Intercellular Communication	Thirty patients (30 eyes) with vitreous haze secondary to intermediate, posterior, or panuveitis; 12 patients (12 eyes) with uveitis but without evidence of vitreous haze; and 18 patients (18 eyes) without intraocular inflammation or vitreoretinal disease.	24835759
Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn, Single organ dysfunction	Altered Intercellular Communication	In the acute respiratory distress syndrome (ARDS), inflammation in the lungs and other organs can cause life-threatening organ failure.	24835849
Inflammation, fibroblast proliferation	Altered Intercellular Communication	Mammalian target of rapamycin (mTOR), a central mediator of inflammation, has been proposed as a novel target to block fibroproliferation.	24835866
Inflammation, Liver carcinoma	Altered Intercellular Communication	Radioembolization of hepatocellular carcinoma activates liver regeneration, induces inflammation and endothelial stress and activates coagulation.	24836705
Inflammation, Hepatobiliary Disorder, Thrombosis, Venoocclusive disease	Altered Intercellular Communication	Radioembolization may rarely induce liver disease resulting in a syndrome that is similar to veno-occlusive disease complicating bone marrow transplantation where inflammation, endothelial cell activation and thrombosis are likely involved.	24836705
Myofibrils, Inflammation, Vascular Diseases, Fibrosis Assessment, Hypertrophic Cardiomyopathy	Altered Intercellular Communication	Semi-quantitative histological analysis revealed no significant differences in the degree of myocardial hypertrophy, myofibrillar loss, fibrosis, small vascular disease, inflammation or fat invasion between LD/DM and non-LD cases.	24836730
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Physical activity influences inflammation, and both affect brain structure and Alzheimer's disease (AD) risk.	24836855
Inflammation, Data types - Address	Altered Intercellular Communication	TNFa, but not physical activity, was associated with regional volumes of the inferior parietal lobule, a region previously associated with inflammation in AD patients.	24836855
Tooth structure, Osteopenia, Pulpitis	Altered Intercellular Communication	This condition causes bone loss around the apex of the tooth, subsequent to pulp inflammation (pulpitis).	24837500
SNCG gene, Inflammation, palladium, Parkinson Disease	Altered Intercellular Communication	Increased gut permeability, inflammation, and colonic a-synuclein pathology are present in early Parkinson's disease (PD) and have been proposed to contribute to PD pathogenesis.	24838182
Inflammation, Atherosclerosis	Altered Intercellular Communication	Heat-shock protein 60 (Hsp60) has been shown to provoke inflammation, and anti-Hsp60 may facilitate the development of atherosclerosis.	24838263
Inflammation, Liver Dysfunction	Altered Intercellular Communication	Because of synthesis by the liver, production of CRP in response to inflammation may be attenuated in patients with liver dysfunction.	24838501
Inflammation, Arthritis	Altered Intercellular Communication	Inhibition of terminal FUTs reshapes the differentiation and functions of M1 macrophages, leading to resolution of inflammation in arthritis.	24838610
Inflammation, Thrombosis, Endothelial dysfunction	Altered Intercellular Communication	It is known that eosinophils play an important role in inflammation, endothelial dysfunction, and thrombosis.	24838897
FBN2 wt Allele	Altered Intercellular Communication	Prostaglandin E2 (PGE2) involves in progression of various chronic inflammation-related cancers including cholangiocarcinoma (CCA).	24839005
Inflammation, Primary malignant neoplasm, Chronic disease	Altered Intercellular Communication	Systemic measures of chronic inflammation, often based on a single blood draw, are frequently used to study the associations between inflammation and chronic diseases such as cancer.	24839050
Inflammation, Hypertrophy	Altered Intercellular Communication	The physical examination revealed marked enlargement with inflammation in his right hemiscrotum.	24841026
Atherogenesis, Inflammation, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Peroxisome proliferator-activated receptor g (PPARg) is a ligand-activated transcription factor involved in the regulation of lipid metabolism, diabetes, obesity, atherogenesis and inflammation.	24841086
Inflammation, Leukocytosis, Fever, CTCAE, Candida (fungus)	Altered Intercellular Communication	We identified patients who from January 2010 to June 2012 had signs of inflammation, such as fever and leukocytosis, and concomitant positive cultures of Candida spp.	24841623
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Matrix metalloproteinases (MMPs) appear to be responsible for much of the extracellular matrix (ECM) degradation observed in the progression of cancer, aging and inflammation.	24841706
Inflammation	Altered Intercellular Communication	Giant cells and chronic sclerosing inflammation were absent.	24841730
Right sided, Inflammation, Arthritis, Psoriatic	Altered Intercellular Communication	A 48-year-old woman who received injections of adalimumab for the treatment of psoriatic arthritis developed right-sided orbital pain and inflammation.	24841734
Inflammation, Swelling	Altered Intercellular Communication	We present a case of 35-year-old young man with diffuse swelling of 3.5x4 cm in the parotid region on the right side of the face with signs of inflammation.	24842360
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	While the presence of secondary signs of inflammation can be used to rule in appendicitis, statistical strength to rule out appendicitis in the absence of secondary signs is insufficient.	24842505
Muscle Rigidity, Inflammation, Fever, CTCAE	Altered Intercellular Communication	Crowned dens syndrome (CDS) is a clinical-radiological entity characterized by acute attacks of neck pain with fever, rigidity, general signs of inflammation, and calcification of the periodontoid articular structures.	24842523
Interstitial inflammation	Altered Intercellular Communication	The impact on graft survival of interstitial inflammation in borderline change of allograft kidneys.	24842816
Interstitial inflammation	Altered Intercellular Communication	In this study, we focused specifically on interstitial inflammation as a factor influencing outcome after diagnosis of BL.	24842816
Interstitial inflammation	Altered Intercellular Communication	Univariate analysis showed that the grade of interstitial inflammation was not a significant risk factor for developing acute rejection (P = 0.816).	24842816
Interstitial inflammation	Altered Intercellular Communication	Our results show that the level of interstitial inflammation does not have an effect on a progressive BL course.	24842816
Interstitial inflammation, Glomerulitis Assessment, Interstitial Fibrosis Assessment, Peritubular Capillaritis Assessment, Tubular atrophy	Altered Intercellular Communication	Peritubular capillaritis was present in 74 BS (86%), transplant glomerulitis in 65 (76%), interstitial fibrosis and tubular atrophy (IF/TA) in 71 (83%), thickening of the peritubular capillary (PTC) basement membrane in 72 (84%), and interstitial inflammation in 40 (47%).	24842817
Glomerulitis Assessment, Inflammation, Peritubular Capillaritis Assessment, Transplant glomerulopathy	Altered Intercellular Communication	We suggest that histopathological changes of transplant glomerulopathy might be accompanied by inflammation of the microvasculature, such as transplant glomerulitis and peritubular capillaritis, thickening of the peritubular capillary basement membrane, and circulating anti-HLA antibodies.	24842817
Tubulitis Assessment, Interstitial inflammation	Altered Intercellular Communication	In the latter, focal interstitial inflammation and severe tubulitis without cytopathic changes were identified outside of SV40-positive areas.	24842821
Inflammation, Bipolar Disorder, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus	Altered Intercellular Communication	The association between depressive symptoms and systemic inflammation in people with type 2 diabetes: findings from the South London Diabetes Study.	24842983
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Bipolar Disorder	Altered Intercellular Communication	Increased inflammation may be involved in the pathogenesis of depressive symptoms in type 2 diabetes and contribute to the increased risk of complications and mortality in this group.	24842983
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Inflammation has been hypothesized to play an important etiological role in the initiation or progression of prostate cancer.	24844401
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Circulating levels of the systemic inflammation marker C-reactive protein (CRP) have been associated with increased risk of prostate cancer.	24844401
Minimal Disseminated Disease, Inflammation, Bipolar Disorder	Altered Intercellular Communication	Significant associations between inflammation and depressive symptoms were found for CRP and IL-6, for the total group and the subgroup of patients with current MDD.	24845191
Inflammation, Rheumatoid Arthritis, Atherosclerosis	Altered Intercellular Communication	Systemic inflammation and cardiovascular risk factors predict rapid progression of atherosclerosis in rheumatoid arthritis.	24845391
Inflammation	Altered Intercellular Communication	CV risk factors may modify the role of systemic inflammation in determining IMT progression over time.	24845391
Sinusitis, Craniosynostosis, Chronic sinusitis	Altered Intercellular Communication	Twelve chronic rhinosinusitis (CRS) patients presenting with maxillary sinus inflammation requiring FESS were enrolled.	24845735
Inflammation, Data types - Address	Altered Intercellular Communication	This finding could be explained by inflammation and/or gliosis in early stages of AD.	24846203
Inflammation, Rheumatic mitral stenosis	Altered Intercellular Communication	In patients with rheumatic mitral stenosis (RMS), ongoing chronic inflammation may resultin the progression of valvular damage and the formation of spontaneous echocardiographic contrast (SEC).	24846361
Inflammation	Altered Intercellular Communication	The formation of SEC is associated with inflammation and NLR is an independent predictive risk factor for SEC.	24846361
Vasculitis	Altered Intercellular Communication	Vasculitides includes a heterogeneous group of disorders with the common histologic findings of vascular wall inflammation.	24846840
vascular inflammations, Vasculitis, CTCAE	Altered Intercellular Communication	Potential isolated gynecologic vasculitis causes include: previous surgical interventions and vascular inflammation secondary to local neoplasm.	24846840
vascular inflammations, Hypertriglyceridemia, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Obesity, hypertriglyceridemia and raised CRP are interrelated suggesting that obesity is not only linked to hypertriglyceridemia but vascular inflammation among pre-obese and obese without overt diabetes mellitus causes high CRP as well and this can be used as a marker to predict the future risk of CAD.	24848386
Inflammation	Altered Intercellular Communication	Recently, we identified novel roles of Substance-P (SP) in the suppression of the injury-mediated inflammation and also in stem cell mobilization.	24849674
Inflammation	Altered Intercellular Communication	Predicted metagenomes of particular microbiota members involved in these compositional shifts indicated exacerbation-associated loss of functions involved in the synthesis of antimicrobial and anti-inflammatory products, alongside enrichment in functions related to pathogen-elicited inflammation.	24850358
Inflammatory Bowel Diseases	Altered Intercellular Communication	Data indicate that SIRT1 is downregulated in IBD patients and colitic mice and suggest that SIRT1 activation can help attenuate inflammatory signals in the gut.	24850427
Inflammation	Altered Intercellular Communication	More needs to be learned about the complex interaction between stress, immune parameters and chronic inflammation.	24850878
Inflammation, Pancreatitis	Altered Intercellular Communication	Mild and moderate severe acute pancreatitis is an illness characterized with chemical inflammation which, in general, passes without major complications.	24851605
Inflammation, Carcinoma of lung, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation is involved in development of lung cancer and cardiovascular disease (CVD), and we hypothesize that self-reported CVD is an independent risk factor for lung cancer.	24852520
Granulomatous inflammation, Granulomatous prostatitis, prostatitis	Altered Intercellular Communication	Granulomatous prostatitis is an unusual form of prostatitis, and xanthogranulomatous prostatitis (XGP) is an even rarer granulomatous inflammation.	24852675
Inflammation, Hantavirus Infections, Sepsis, HHH syndrome, Hematological Disease	Altered Intercellular Communication	These findings suggest that HHH is a different entity from HPS and that it preferentially develops under conditions of excessive inflammation and its associated risks, such as hematological diseases and sepsis.	24852692
Fibrosis Assessment, Tubular atrophy, Albuminuria	Altered Intercellular Communication	Albuminuria may further lead to tubulointerstitial inflammation, fibrosis and tubular atrophy.	24853042
Inflammation, Gastrointestinal inflammation	Altered Intercellular Communication	Inhibition of inflammation with IFX would reduce the bacterial toxins via improvement of intestinal inflammation.	24853095
Inflammation	Altered Intercellular Communication	There was a significant persistent correlation between endoscopic inflammation and fecal calprotectin (p = 0.003 at inclusion and p < 0.001 at follow-up).	24853318
Inflammation	Altered Intercellular Communication	CRP was correlated to endoscopic inflammation at inclusion (p = 0.006), but not at follow-up.	24853318
Shock, Inflammation, Metabolic acidosis	Altered Intercellular Communication	We have identified two subphenotypes within ARDS, one of which is categorised by more severe inflammation, shock, and metabolic acidosis and by worse clinical outcomes.	24853585
Pseudotumor, Orbital Pseudotumor	Altered Intercellular Communication	IgG4-related orbital inflammation presenting as unilateral pseudotumor.	24854367
Swelling	Altered Intercellular Communication	It is an inflammatory condition of unknown etiology characterized by tumorous swelling of the organs, characteristic histopathologic changes and elevated IgG4: IgG plasma cells ratio.	24854367
Chronic Kidney Diseases	Altered Intercellular Communication	Soluble TM may play critical roles in the development of CKD, as a biomarker of endothelial cells damage, anticoagulation and anti-inflammation.	24854597
Inflammation, Acute inflammation, Pancreatitis, Alcoholic	Altered Intercellular Communication	The possibility of acute bacterial inflammation should be considered in all cases of chronic alcoholic pancreatitis who present with severe features of inflammation, even in the early stages of an attack.	24854608
Inflammation, Depression, CTCAE, Bipolar Disorder	Altered Intercellular Communication	Depressive symptoms are associated with inflammation yet the association between inflammation and different levels of depression remains unclear.	24856570
Inflammation	Altered Intercellular Communication	Among participants not taking anti-depressants, subsyndromal depression is not associated with inflammation.	24856570
Inflammation, Bipolar Disorder	Altered Intercellular Communication	However, depressive symptoms measured by CES-D>=16 are associated with a lower inflammation (CRP).	24856570
Inflammation, Neoplasms	Altered Intercellular Communication	Risk factors were identified in 92 patients (79%) including prior surgery, inflammation, and extensive tumor.	24857278
Prolactinoma, "Pituitary-dependent Cushings disease", Acromegaly	Altered Intercellular Communication	Hormonal remission was achieved in 16 patients with Cushing disease (84%), 18 patients with prolactinoma (78.2%), and 18 patients with acromegaly (85,7%).	24857341
Inflammation, Sinusitis	Altered Intercellular Communication	Sinusitis is defined as a condition manifested by inflammation of the mucous membrane of the nose & paranasal sinuses, fluid within this cavities and or underlying bone.	24858147
Degenerative polyarthritis, Inflammation, Cartilage damage	Altered Intercellular Communication	Altogether, our findings support a beneficial effect of HA/sorbitol in OA through the restoration of redox status and reduction of apoptosis, inflammation and catabolism involved in cartilage damage.	24858301
Inflammation	Altered Intercellular Communication	Telomere attrition has been associated with age-related diseases, although causality is unclear and controversial; low-grade systemic inflammation (inflammaging) has also been implicated in age-related pathogenesis.	24858709
Inflammation	Altered Intercellular Communication	Telomere attrition has been associated with age-related diseases, although causality is unclear and controversial; low-grade systemic inflammation (inflammaging) has also been implicated in age-related pathogenesis.	24858709
Sepsis, Inflammation, Hyperinsulinism, Hypoxia	Altered Intercellular Communication	However, its expression reportedly varies in response to a range of pathophysiological variables (inflammation, oxidative stress, hyperinsulinaemia, hypoxia) which feature prominently in sepsis.	24858725
Inflammation, Traumatic injury	Altered Intercellular Communication	Mediators of inflammation have been postulated as playing a key role in being responsible for life threatening complications of multiple trauma patients.	24858965
Inflammation, Dyssomnias, Medically Unexplained Symptoms, Bipolar Disorder, Fatigue	Altered Intercellular Communication	Our findings indicate that the link between depressive symptoms and systemic inflammation may be due to the somatic symptoms of sleep disturbance, fatigue, appetite changes, and psychomotor retardation/agitation and may be strongest among non-Hispanic Whites.	24859042
Inflammatory Bowel Diseases, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Expression stability of common housekeeping genes is differently affected by bowel inflammation and cancer: implications for finding suitable normalizers for inflammatory bowel disease studies.	24859296
Primary malignant neoplasm, Colitis	Altered Intercellular Communication	Colon inflammation affected HKG more pronouncedly than cancer with ACTB significantly down- and B2M upregulated.	24859296
Sleep-Disordered Breathing, Inflammation, Hypoxia, Cardiovascular Diseases	Altered Intercellular Communication	Sleep disordered breathing, hypoxia and inflammation: associations with sickness behaviour in community dwelling elderly with and without cardiovascular disease.	24859483
Inflammation, Pain Distress Question, Illness Behavior, Syndrome, Sleep disturbances, Bipolar Disorder, Fatigue	Altered Intercellular Communication	Inflammation can induce a cluster of symptoms, referred to as sickness behaviour (e.g., depressive symptoms, sleep disturbances, pain and fatigue).	24859483
Sleep-Disordered Breathing, Inflammation, Hypoxia, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	CVD is associated with an increased inflammatory activity and in SDB, hypoxia can also increase inflammation.	24859483
Inflammation, Hypoxia	Altered Intercellular Communication	The purpose of this study is to explore if SDB-related hypoxia is associated differently with inflammation and the presence of sickness behaviour in older adults with and without CVD.	24859483
Illness Behavior, Inflammation, Hypoxia, Bipolar Disorder	Altered Intercellular Communication	Structural Equation Modelling showed that SDB-related hypoxia was associated with inflammation (b > 0.40) which mediated indirect associations with sickness behaviour (b = 0.19) and depressive symptoms (b = 0.11), but only in those with CVD (n = 119).	24859483
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Considerable evidence has suggested that chronic inflammation is a causative factor in the development of human colorectal cancer (CRC).	24859972
Orchitis	Altered Intercellular Communication	The entheses represent the initial site of articular inflammation and the enthesis of the Achilles tendon is the first to be affected.	24861143
Chronic inflammation	Altered Intercellular Communication	Pentraxin (PTX) 3 is an acute phase protein known to be associated with chronic inflammation.	24861165
Inflammation, Spondylitis	Altered Intercellular Communication	This study was performed to test the hypothesis that serum PTX3 levels might be elevated as a marker of inflammation in patients with ankylosing spondylitis.	24861165
Inflammation, Spondylitis	Altered Intercellular Communication	These results are supportive of the hypothesis that levels of serum PTX 3 might be elevated in association with inflammation in patients with ankylosing spondylitis; however, results also demonstrate that there is no significant correlation with disease activity.	24861165
Inflammation, Pneumonia, Interstitial, Pulmonary Fibrosis	Altered Intercellular Communication	Interstitial pneumonia (IP) is characterized by various degrees of pulmonary fibrosis and inflammation.	24861259
Gingivitis, Periodontitis	Altered Intercellular Communication	In Case 1, generalized chronic periodontitis with severe gingival inflammation was treated with azithromycin before periodontal treatment.	24861402
Gingivitis	Altered Intercellular Communication	This property may be independent of the degree of baseline gingival inflammation.	24861402
Malignant neoplasm of urinary bladder, Transitional cell carcinoma of bladder, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	To assess whether polymorphisms of the interleukin-23 receptor (IL23R) gene are associated with bladder transitional cell carcinoma because chronic inflammation contributes to bladder cancer and the IL23R is known to be critically involved in the carcinogenesis of various malignant tumors.	24861772
Inflammation, Carcinogenesis, Neoplasms	Altered Intercellular Communication	Inflammation mediated by the immune system is known to be important in carcinogenesis and, specifically, T helper 17 cells have been reported to play a role in tumor progression by promoting neo-angiogenesis.	24861949
Airway structure, Asthma, Respiration Disorders	Altered Intercellular Communication	Bronchial asthma is a chronic respiratory disease characterized by airway inflammation.	24863266
Airway structure, Disease	Altered Intercellular Communication	There is increasing evidence that neurotrophins play an important role in the development and maintenance of neurogenic airway inflammation in chronic allergic diseases.	24863266
Hyperlipidemia, Hepatic inflammation	Altered Intercellular Communication	Consumption of trans-fat for 20 weeks resulted in remarkable hyperlipidemia, elevation of serum cholesteryl ester transfer protein activity, hepatic inflammation, and fatty liver changes.	24863413
Hyperlipidemia, Inflammation, Each (qualifier value), Toxic effect	Altered Intercellular Communication	In zebrafish, EA-rHDL resulted in acute embryonic toxicity, and consumption of EA caused remarkable hyperlipidemia, inflammation, and fatty liver changes.	24863413
Restless Legs Syndrome	Altered Intercellular Communication	The scarcity of this alpha-synuclein gain-of-function variant in RLS might suggest that a low alpha-synuclein function via the SNARE complex in presynaptic vesicle release and neurotransmission of the striatum contributes to RLS pathogenesis.	24863655
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Low-grade dietary-related inflammation and survival after colorectal cancer surgery.	24863751
Inflammation	Altered Intercellular Communication	Prolong inflammation is a central process observed in several chronic conditions and may be responsible for survival.	24863751
Inflammation	Altered Intercellular Communication	There is an increasing evidence showing the role of diet in inflammation and habitual diet may be responsible for low-grade inflammation.	24863751
Inflammation, Vasculitis, CTCAE, Systemic Vasculitis	Altered Intercellular Communication	Microscopic polyangiitis (MPA) is a systemic necrotizing vasculitis characterised by inflammation of the small blood vessels, the absence of granulommas on histopathological specimens, with few or no immune deposits and the presence of circulating anti-neutrophil cytoplasmic antibodies (ANCAs).	24863847
Chronic kidney disease stage 5, Kidney Failure, Chronic	Altered Intercellular Communication	Women with End Stage Renal Disease (ESRD) have hormonal imbalance leading to gynaecological and reproductive disturbances.	24864612
Inflammation	Altered Intercellular Communication	There was high prevalence of humoral immune alterations both in local and systemic response to chronic inflammation in the patients, which suggests that assessment of immunoglobulin before clinical evaluation and management could be important.	24864628
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic inflammation of the lung is a characteristic finding in chronic obstructive pulmonary disease (COPD).	24865134
Eosinophilic inflammation	Altered Intercellular Communication	Macroscopic examination of the pleura showed diffuse thickening with pleural plaques in eight patients, consistent with diffuse pleural eosinophilic inflammation histologically proven.	24865235
Inflammation, Fibrosis Assessment, Tubular atrophy	Altered Intercellular Communication	The light microscopy study of the renal parenchyma in the MMA kidney revealed extensive interstitial fibrosis, chronic inflammation, and tubular atrophy.	24865477
Orbital Pseudotumor	Altered Intercellular Communication	Effect of hemodiafiltration with endogenous reinfusion on overt idiopathic chronic inflammation in maintenance hemodialysis patients: a multicenter longitudinal study.	24865622
Orbital Pseudotumor	Altered Intercellular Communication	These features could be helpful in MHD patients affected by idiopathic chronic inflammation, but this issue remains to be elucidated.	24865622
Inflammation, Orbital Pseudotumor	Altered Intercellular Communication	In MHD patients affected by idiopathic chronic inflammation the switching from BHD to HFR is associated with improvement of inflammation.	24865622
Inflammation, Immunodeficiency-Related Disorder	Altered Intercellular Communication	This is attributed to inflammation and immunodepression due to medications.	24866077
Parkinson Disease, Nail-Patella Syndrome, palladium	Altered Intercellular Communication	Neuropsychiatric symptoms (NPS) in Parkinson's disease (PD) have been mostly attributed to neurotransmitter imbalances.	24866458
Airway structure, Asthma	Altered Intercellular Communication	The CRTH2 antagonist OC000459 has previously been demonstrated to reduce airway inflammation and improve lung function in moderate persistent asthma.	24866478
Inflammation	Altered Intercellular Communication	Protein malnutrition was identified as an additional factor associated with retinal venular dilatation beyond inflammation.	24867580
Pain Distress Question, Inflammation, Fever, CTCAE, Kyphoscoliosis deformity of spine, Congenital Abnormality, Structure of pelvic girdle, Symptoms, Erythema, Hallux structure	Altered Intercellular Communication	The clinical symptoms include pain and inflammation of the soft tissue, sometimes associated with fever and cutaneous erythema, joint symptoms--pain, stiffness most frequently concerning the scapular and pelvic girdle, bone malformations--short hallux, microdactilia, kyphoscoliosis, thorax malformations.	24868261
ARCN1 gene, Inflammation	Altered Intercellular Communication	The 13 lipids with a high fold change between smokers with and without COPD showed high correlations with lower lung function and inflammation in sputum.	24871890
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	There is an increased airway inflammation in the pathogenesis of chronic obstructive pulmonary disease (COPD), and it has been suggested that there may also be problem in the apoptosis and renewal of cells.	24871992
Inflammation, Granuloma	Altered Intercellular Communication	The pathological diagnoses of 14 false-positive cases by FDG-PET were chronic inflammation in 12 and non-specific granuloma in 2.	24872477
Inflammation, Infection	Altered Intercellular Communication	Cytokine production assays reveal discriminatory immune defects in adults with recurrent infections and noninfectious inflammation.	24872512
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic neutrophilic inflammation is a hallmark in the pathogenesis of chronic obstructive pulmonary disease (COPD) and persists after cigarette smoking has stopped.	24874071
ARCN1 gene, Inflammation	Altered Intercellular Communication	We investigated changes to the leukotriene A4 hydrolase (LTA4H)-proline-glycine-proline (PGP) pathway and chronic inflammation in the development of COPD.	24874071
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Mice exposed to cigarette smoke developed emphysema with increased PGP, neutrophilic inflammation, and selective inhibition of LTA4H aminopeptidase, which ordinarily degrades PGP.	24874071
Inflammation, Glaucoma, CTCAE, Ocular surface disease	Altered Intercellular Communication	Deep corneal vascularization (P = .012), preexisting active inflammation (P = .023), preexisting glaucoma drainage device (P = .023), and preexisting ocular surface disease (P = .037) were associated with reduced graft survival in a univariate analysis.	24875001
vascular inflammations	Altered Intercellular Communication	Estrogen effects on vascular inflammation are age dependent: role of estrogen receptors.	24876352
vascular inflammations	Altered Intercellular Communication	We hypothesize that E2 effects on vascular inflammation are age dependent.	24876352
Inflammation, Amyloidosis	Altered Intercellular Communication	Amyloidosis, inflammation, and oxidative stress in the heart of an alkaptonuric patient.	24876668
Inflammation	Altered Intercellular Communication	Immunofluorescence detected lipid peroxidation of the tissue and lymphocyte/macrophage infiltration causing inflammation.	24876668
Autoimmune Diseases, Inflammation, Acute myocardial infarction, Ischemic stroke	Altered Intercellular Communication	Autoimmune rheumatic diseases (ARD) are characterized by systemic inflammation and may affect multiple organs and cause vascular events such as ischemic stroke and acute myocardial infarction.	24877143
Inflammation, Fibrosis Assessment, Coronary Arteriosclerosis	Altered Intercellular Communication	The inflammation and fibrosis, in combination with concomitant atherosclerotic disease, resulted in severe stenosis of the coronary arteries.	24878025
Airway structure	Altered Intercellular Communication	However, the effect of ambient metals exposure on airway inflammation, and how these associations may be modified by seroatopy, has not been determined.	24878380
Airway structure	Altered Intercellular Communication	Fractional exhaled nitric oxide (FENO) is a reliable proxy marker of airway inflammation.	24878380
Communicable Diseases, Inflammation, HIV Infections, GRN wt Allele	Altered Intercellular Communication	PGRN production is also modulated by inflammation and infection, but no data are available on the production and role of PGRN during CNS HIV infection.	24878635
Inflammation, HIV Infections, GRN wt Allele	Altered Intercellular Communication	To determine the relationships between PGRN and HIV disease, neurocognition, and inflammation, we analyzed 107 matched CSF and plasma samples from CHARTER, a well-characterized HIV cohort.	24878635
Inflammation, Malnutrition	Altered Intercellular Communication	Free triiodothyronine in hemodialysis patients: link with malnutrition and inflammation.	24878944
Inflammation, Malnutrition	Altered Intercellular Communication	There is lack of data about the link between FT3 levels and malnutrition and inflammation in hemodialysis patients.	24878944
Comorbidity	Altered Intercellular Communication	Patients' comorbidity status was determined using the Charlson Comorbidity Index (CCI), and malnutrition-inflammation status was determined by Malnutrition-Inflammation Score (MIS).	24878944
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Of the 199 procedures, 4 appendectomies were negative (histologically normal), 182 were positive (primary appendicitis) and 13 were incidental (another primary process caused inflammation).	24879063
Tubulitis Assessment, Interstitial inflammation, Glomerulitis (disorder)	Altered Intercellular Communication	On 1-year protocol biopsies, the dnDSA group showed more interstitial inflammation, tubulitis, and glomerulitis.	24879384
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	In addition, 1 biopsy had lichenoid inflammation in the epidermis and the other had evidence of vasculitis.	24879511
Musculoskeletal Pain, Muscular stiffness, Ache	Altered Intercellular Communication	Polymyalgia rheumatica (PMR) is an idiopathic systemic inflammatory condition manifesting as aches and muscle stiffness of the proximal muscle groups.	24879730
Inflammation	Altered Intercellular Communication	Localization of PC (16:0/16:0) might reflect inflammation activity participating in the pathogenesis of War-T.	24880872
Airway structure, Acute asthma	Altered Intercellular Communication	A human monoclonal anti-TNF alpha antibody (adalimumab) reduces airway inflammation and ameliorates lung histology in a murine model of acute asthma.	24882395
Alveolus, Inflammation	Altered Intercellular Communication	Lung parenchyma, alveolus, peribronchial and perivascular inflammation were assessed.	24882395
Inflammation, Chronic purulent otitis media	Altered Intercellular Communication	Mucosae from the CSOM group presented chronic inflammation or suppurative inflammation in the rudimentary stroma, mainly with infiltration of monocytes and macrophages.	24882571
Inflammation, Chronic purulent otitis media	Altered Intercellular Communication	Reduced TLR levels in the middle-ear mucosa might cause weak host response to bacteria, persistent inflammation and susceptibility to CSOM.	24882571
Inflammation, Manufactured sign	Altered Intercellular Communication	Records from 181 patients with ocular signs and symptoms suggestive of TRU and intraocular inflammation of unknown etiology were reviewed.	24882956
Intraocular inflammation, Retinal Vasculitis, Uveitis	Altered Intercellular Communication	The positive predictive value of the IGRA among patients with intraocular inflammation was high (70%) when all of younger age (<= 40 years), posterior uveitis, and retinal vasculitis were present.	24882956
Acquired Immunodeficiency Syndrome, Myositis, Muscular Atrophy, Malignant Neoplasms, Chronic disease	Altered Intercellular Communication	Muscle wasting is frequently a result of cancers, AIDS, chronic diseases and aging, which often links to muscle inflammation.	24884473
Muscular Atrophy, Chronic inflammation, Muscle (organ)	Altered Intercellular Communication	GSE supplementation effectively prevents muscle wasting in IL10KO mice, showing that GSE can be used as an auxiliary treatment for muscle loss associated with chronic inflammation and frailty.	24884473
Refractory anemias, Autoimmune Diseases, Synovial joint structure, Rheumatoid Arthritis, Chronic destructive inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic destructive inflammation in synovial joints.	24884566
Retinal Vein Occlusion, Inflammation, Edema	Altered Intercellular Communication	Role of inflammation in previously untreated macular edema with branch retinal vein occlusion.	24884703
Inflammation, Edema	Altered Intercellular Communication	The relationship between the aqueous flare value and the vitreous fluid levels of vascular endothelial growth factor (VEGF), interleukin (IL)-6, monocyte chemotactic protein (MCP)-1, soluble intercellular adhesion molecule 1 (sICAM-1), and soluble VEGF receptor-2 (sVEGFR-2) was evaluated to investigate the role of inflammation in BRVO associated with macular edema.	24884703
Inflammation, Macular retinal edema	Altered Intercellular Communication	Inflammation may induce an increase of vascular permeability and disrupt the blood-aqueous barrier via release of inflammatory factors (VEGF, IL-6, MCP-1, and sICAM-1) in BRVO patients with macular edema.	24884703
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	A disadvantaged social position in childhood, as measured by father's manual occupation, was associated at conventional levels of statistical significance with an increased risk of type 2 diabetes in adulthood, both directly and indirectly through inflammation, adulthood social position and a risk score constructed from adult health behaviours including tobacco smoking and limited physical activity.	24884735
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	At the present stage of study of chronic obstructive pulmonary disease (COPD) one of the problem is the definition of new criteria for the topical and systemic chronic inflammation of this disease.	24884928
Amyotrophic Lateral Sclerosis, Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	The involvement of inflammation in the pathogenesis of neurodegenerative diseases, including ALS, is increasingly recognized but still not well understood.	24884937
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Antibiotic treatment reduced humoral inflammation, but failed to resolve her fever.	24885004
Immobile, Endocrine System Diseases, Chronic disease, Osteoporosis	Altered Intercellular Communication	Etiological factors responsible for osteoporosis secondary to chronic illness include immobility, pubertal delay and other hormonal disturbances.	24885558
Gestational Diabetes, Inflammation	Altered Intercellular Communication	Integrative analysis of the transcriptome profiles observed in type 1, type 2 and gestational diabetes mellitus reveals the role of inflammation.	24885568
Gestational Diabetes, Inflammation, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8	Altered Intercellular Communication	The functional analyses were able to discriminate between T1D and GDM patients based on genes involved in inflammation.	24885568
Inflammation, Bronchial Hyperreactivity, Familial Hypophosphatemic Rickets	Altered Intercellular Communication	A mutated vitamin D receptor in hereditary vitamin D-resistant rickets prevents induction of bronchial hyperreactivity and inflammation.	24885630
Inflammation, Familial Hypophosphatemic Rickets, Allergy - Charge Type Reason	Altered Intercellular Communication	The aim of the study was to determine the role of the VDR on lung functions, airways, and systemic markers of inflammation and allergy in HVDRR patients.	24885630
Inflammation	Altered Intercellular Communication	In this case, increased (18) F-FDG uptake is more likely to appear, particularly if the inflammation is predominant.	24885757
Pneumonitis	Altered Intercellular Communication	Altogether, the data reported here strongly suggest that welding-related NP could be responsible, at least in part, for the pulmonary inflammation observed in welders.	24885771
Neoplasm Metastasis	Altered Intercellular Communication	For shorter OS, synchronous metastasis (HR 3.05, 95% CI 1.07-11.94, p = 0.048) and inflammation-based prognostic score (HR 6.65, 95% CI 1.25-35.23, p = 0.026) were identified as independent prognostic factors.	24885814
Neurodegenerative Disorders, Inflammation, Cardiovascular Diseases, Diabetes Mellitus, Transient Ischemic Attack	Altered Intercellular Communication	The same biological responses thought to effect cardiovascular disease through air pollution-mediated systemic oxidative stress, inflammation and cerebrovascular dysfunction could also be relevant for diabetes and neurodegenerative diseases.	24886318
Inflammation, Arthritis, Gouty, Collagen Diseases	Altered Intercellular Communication	This study investigates the impact of serum uric acid, inflammation and traditional CV risk parameters on CV event risk in patients with gouty arthritis and patients with non-gouty rheumatic disease.	24886363
ARCN1 gene, Inflammation, Bronchiectasis, Airway structure, Bacterial Infections, Damage	Altered Intercellular Communication	In contrast to other chronic airway infections, associated with COPD and CF bronchiectasis, where polymicrobial communities have been implicated in lung damage due to the vicious circle of recurrent bacterial infections and inflammation, there is sparse information on the composition of bacterial communities in NCFBr.	24886473
Vascular Diseases, Inflammation, Atherosclerosis	Altered Intercellular Communication	If endothelial cells are excessively activated, it may lead to vasculopathic diseases, such as pathologic angiogenesis, inflammation, and atherosclerosis.	24886494
Inflammation, bone destruction, Synovitis	Altered Intercellular Communication	For example, MCP-1 and IL-6 were associated with both general inflammation and bone destruction, in contrast to MIP-1b, which was involved solely in general synovitis.	24886513
Myositis	Altered Intercellular Communication	To explore this hypothesis we compared IMAT and muscular inflammation in age-and BMI-matched older non-obese frail and non-frail adults.	24886741
Myositis	Altered Intercellular Communication	Non-obese, older, frail individuals have increased IMAT and muscular inflammation when compared to their non-frail, age- and BMI-matched peers.	24886741
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Biopsies were scored for presence of inflammation, necrotic muscle fibers, rimmed vacuoles, fibrosis, and immunohistochemical staining.	24886750
Inflammation	Altered Intercellular Communication	In addition, we found that necrotizing muscle fibers with inflammation characterize SSc-PM overlap in muscle biopsies.	24886750
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Further research should focus on underlying mechanisms causing necrosis, inflammation, and fibrosis and their relation to pulmonary involvement and mortality in patients with SSc-PM overlap.	24886750
Delirium, Critical Illness	Altered Intercellular Communication	Inflammation biomarkers and delirium in critically ill patients.	24886875
Delirium, Inflammation, Critical Illness, septic	Altered Intercellular Communication	The aim of this investigation was to study the relationship between systemic inflammation and the development of delirium in septic and non-septic critically ill patients.	24886875
Inflammation, Hemorrhage, Edema	Altered Intercellular Communication	Hemorrhages, vessel fibrinoid necrosis, perivascular fibrin exudation, edema and neutrophilic inflammation are early features, while perivascular demyelination, microglial foci and myelin-laden macrophages appear later.	24887055
Inflammation, Hemorrhage, Edema	Altered Intercellular Communication	Severe hemorrhages, edema and neutrophilic inflammation in the absence of circumscribed perivascular demyelination affected the temporal neocortex and white matter, hippocampus, cerebellar cortex and white matter, optic chiasm, mammillary bodies, brainstem, cranial nerve roots and leptomeninges.	24887055
Loss of myelin, Inflammation, Damage, MS gene	Altered Intercellular Communication	Inflammation and complement activation are firmly implicated in the pathology of multiple sclerosis; however, the extent and nature of their involvement in specific pathological processes such as axonal damage, myelin loss and disease progression remains uncertain.	24887075
Inflammation, Chronic active	Altered Intercellular Communication	Active, chronic active and chronic inactive multiple sclerosis plaques (35 in total) and non-plaque areas were examined.Multiple sclerosis plaques were consistently positive for complement proteins (C3, factor B, C1q), activation products (C3b, iC3b, C4d, terminal complement complex) and regulators (factor H, C1-inhibitor, clusterin), suggesting continuing local complement synthesis, activation and regulation despite the absence of other evidence of ongoing inflammation.	24887075
Inflammation, Hypoxia	Altered Intercellular Communication	The finding that the human carotid body releases cytokines in response to hypoxia adds to the growing body of information suggesting that the carotid body may play a role in detecting inflammation, providing a link between the immune system and the nervous system.	24887113
Hypoxemia, Pneumonitis	Altered Intercellular Communication	Furthermore, S100A12 levels were associated with increased levels of markers of pulmonary inflammation, prolonged cardiopulmonary bypass, hypoxemia and duration of mechanical ventilation.	24887223
Acute Lung Injury, Hypoxia, Pneumonitis	Altered Intercellular Communication	S100A12 is associated with duration of cardiopulmonary bypass, pulmonary inflammation, hypoxia and prolonged mechanical ventilation and may contribute to acute lung injury in cardiac surgery patients.	24887223
Proteinuria, Inflammation, Adult Non-Hodgkin Lymphoma	Altered Intercellular Communication	Proteinuria is a simple sign of systemic inflammation that leads to a poor prognosis in individuals affected with non-Hodgkin lymphoma.	24887301
Proteinuria, Inflammation, RTEL1 gene	Altered Intercellular Communication	Proteinuria is a simple sign of coexisting systemic inflammation due to NHL and a harbinger of a poor prognosis.	24887301
Inflammation, Pneumonia, Parkinson Disease, palladium, Delirium, Respiratory Tract Infections	Altered Intercellular Communication	In Parkinson disease (PD), systemic inflammation caused by respiratory infections such as pneumonia frequently occurs, often resulting in delirium in the advanced stages of this disease.	24887491
Symptoms, Inflammation	Altered Intercellular Communication	Inflammation causes rapid worsening of PD motor symptoms and signs, sometimes irreversibly in some, but not all, patients.	24887491
palladium, Inflammation	Altered Intercellular Communication	To identify factors associated with subacute motor deterioration in PD patients with systemic inflammation.	24887491
palladium, Inflammation, Motor deterioration	Altered Intercellular Communication	Of 80 PD patients with systemic inflammation, 26 with associated subacute motor deterioration were designated as cases and the remainder as controls.	24887491
Delirium, Inflammation, Motor deterioration	Altered Intercellular Communication	Multivariable logistic regression analysis showed that delirium and body temperature are significantly associated with motor deterioration after systemic inflammation (P = 0.001 for delirium and P = 0.026 for body temperature), the adjusted odds ratios being 15.89 (95% confidence interval [CI]: 3.23-78.14) and 2.78 (95% CI: 1.13-6.83), respectively.	24887491
palladium, Inflammation, Delirium, Motor deterioration	Altered Intercellular Communication	In patients with PD and systemic inflammation, delirium and high body temperature are strong risk factors for subsequent subacute motor deterioration and such deterioration can persist for over 6 months.	24887491
Inflammation, Hemorrhage, Obstruction, Perforation (observation)	Altered Intercellular Communication	Complications were defined as those that presented with inflammation, bleeding, obstruction, or perforation.	24887799
Inflammation, Hemorrhage, Cerebrovascular accident	Altered Intercellular Communication	Late diagnosis resulted in severe hemorrhage and postoperative cerebrovascular accident because of the impossibility of repairing the carotid artery due to severe local inflammation.	24887873
Communicable Diseases, Inflammation, Pneumonia	Altered Intercellular Communication	Pneumonia is a disease causing serious inflammation and infection of the lungs and accounts for >50,000 mortalities annually.	24888337
Inflammation, Pneumonia, Community acquired pneumonia	Altered Intercellular Communication	Pneumonia is more serious in the elderly than in any other age group due to the increased inflammation and risk of community-acquired pneumonia associated with aging.	24888337
NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology, Inflammation, Anemia, Miller Dieker syndrome	Altered Intercellular Communication	Interleukin-6 (IL-6) may play an important role in the pathophysiology of anemia of inflammation associated with myelodysplastic syndrome (MDS).	24888488
Extrinsic allergic alveolitis, Bronchitis	Altered Intercellular Communication	Bronchial inflammation in hypersensitivity pneumonitis after antigen-specific inhalation challenge.	24890329
Bronchitis	Altered Intercellular Communication	This study shows that bronchial inflammation is present in patients with HP evidenced by increases in sputum neutrophils and eosinophils following exposure to the offending antigen during SIC.	24890329
Waldenstrom Macroglobulinemia	Altered Intercellular Communication	Mild lymphoplasmacytic inflammation and few scattered lymphoid aggregates were present, but we found no pathognomonic histopathologic features of anti-EJ ARS syndrome.	24891607
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Lung diseases	Altered Intercellular Communication	COPD (chronic obstructive pulmonary disease) is a common lung disease characterized by airflow limitation and systemic inflammation.	24891763
Inflammation	Altered Intercellular Communication	Recently, adipose tissue mediated inflammation has gathered increasing interest in the pathogenesis of the disease.	24891763
ARCN1 gene, Inflammation	Altered Intercellular Communication	The present results introduce adipocytokines NUCB2/nesfatin-1 and visfatin as novel factors associated with systemic inflammation in COPD and suggest that visfatin may mediate impaired pulmonary diffusing capacity.	24891763
Inflammation, Orbital Cellulitis	Altered Intercellular Communication	Dacryops infection is a rare but important consideration in the differential of a mass lesion in the upper fornix associated with inflammation that may be confused with orbital cellulitis or abscess.	24892277
Inflammation, Infiltration, Edema	Altered Intercellular Communication	Electron microscopic features include blunted epithelial microvilli, numerous fibroblasts, extensive and irregularly arranged collagen bundles, mononuclear infiltration in the vicinity of fibroblasts or in between collagen bundles, and inter- and intracellular edema in areas of inflammation.	24892278
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Chronic inflammation and subsequent fibrosis appear to be the basic ultrastructural response to various noxious stimuli.	24892278
Perimenopausal state, Inflammation, Depression, CTCAE	Altered Intercellular Communication	This negative finding in perimenopausal depression indicates either the absence or a more complex nature of the interactions between acute-phase proteins, low-grade inflammation and depression.	24894416
Inflammation, Asthma	Altered Intercellular Communication	Inflammation in the small airways might contribute to incomplete asthma disease control despite intensive treatment in some subgroups of patients.	24894594
Inflammation, Asthma	Altered Intercellular Communication	Exhaled NO (FeNO) is a marker of inflammation in asthma and the estimated NO contribution from small airways (CalvNO ) is believed to reflect distal inflammation.	24894594
Myositis, CTCAE 5.0, Pneumonitis	Altered Intercellular Communication	A positive association was found between HLA-DQA10104 and DM (p = 0.01; corrected p (pcorr) NS; odds ratio (OR) = 2.58; 95% confidence interval (CI): 1.18-5.64), while an inverse correlation was noted between HLA-DQB10303 and myositis patients with interstitial lung inflammation (p = 0.01; pcorr NS; OR = 0.25; 95% CI: 0.07-0.73).	24894810
Inflammation, Jaw claudication	Altered Intercellular Communication	Jaw claudication correlated moderately with inflammation of the temporalis muscle (r = 0.31; p < 0.05) and the deep temporal artery (r = 0.38; p = 0.01).	24895039
Myositis	Altered Intercellular Communication	* Approximately 20 % of GCA patients presented with temporalis muscle inflammation.	24895039
Vasculitis, CTCAE, Myositis	Altered Intercellular Communication	* MRI is a suitable tool for the assessment of vasculitis and muscle inflammation.	24895039
Inflammation	Altered Intercellular Communication	These findings suggest a protective role of DC in post-MI inflammation and the subsequent healing process.	24895162
Inflammation, Fibrosis Assessment, Graves Disease	Altered Intercellular Communication	Histopathological analysis revealed chronic inflammation and fibrosis consistent with Graves disease.	24896772
Immediate hypersensitivity	Altered Intercellular Communication	Our results indicate that secondary allergen-specific IgE production and IgE-mediated allergic inflammation do not require a fully functional CD4+ T lymphocyte repertoire.	24896832
Inflammation, Squamous cell carcinoma of esophagus	Altered Intercellular Communication	Our results suggested that whole genome hypomethylation caused by chronic inflammation could initiate carcinogenesis of esophageal squamous cells through chromosomal instability.	24898425
Inflammation, Deep Vein Thrombosis, Venous Insufficiency	Altered Intercellular Communication	Inflammation may also be involved in venous insufficiency apart from deep-vein thrombosis.	24898679
Inflammation, Venous Insufficiency	Altered Intercellular Communication	We studied the association of inflammation markers with venous insufficiency in a general population sample.	24898679
Disorder of vein, Congenital Abnormality	Altered Intercellular Communication	Inflammation markers, C-reactive protein (CRP), fibrinogen, interleukin 1-beta (IL-1-beta), IL-8, IL-10, intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), E-selectin, monocyte chemoattractant-1 (MCP-1) and vascular endothelial cell growth factor (VEGF) were compared in 352 case participants with peripheral venous disease and 352 controls with no venous abnormalities frequency matched to cases by age, sex and race.	24898679
Disorder of vein, Inflammation	Altered Intercellular Communication	In conclusion, a subset of inflammation markers were associated with increased risk of peripheral venous disease, suggesting potential therapeutic targets for treatment.	24898679
Cerebrovascular accident	Altered Intercellular Communication	Our results strongly suggest that the abnormal expression of CD137L on monocytes may lead to dyregulated CD137L/CD137 signaling and consequently form part of a positive-feedback, inflammation-promoting circuit in stroke, while the elevated sCD137L protein levels may function as a self-regulatory mechanism of CD137/CD137L interaction and costimulation.	24899613
Inflammation	Altered Intercellular Communication	At low concentrations, oxypurinol should reduce inflammation, but high concentrations may contribute to oxidative stress.	24899662
Inflammation, Demyelination, Nerve Degeneration	Altered Intercellular Communication	Multiple sclerosis deep grey matter: the relation between demyelination, neurodegeneration, inflammation and iron.	24899728
Diffuse Axonal Injury, Inflammation	Altered Intercellular Communication	In addition, detailed analyses of inflammation, acute axonal injury, iron deposition and oxidative stress were performed.	24899728
Cerebral cortex	Altered Intercellular Communication	Deep grey matter inflammation was intermediate between low inflammatory cortical lesions and active white matter lesions.	24899728
Malignant - descriptor, Inflammation	Altered Intercellular Communication	However, in cases with more pronounced inflammation during treatment, targeted biopsies indicated very early malignant alterations.	24900953
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Our dedicated pathologist designed a score to quantify fibrosis and inflammation of pancreatic tissue.	24900974
Inflammation	Altered Intercellular Communication	Systemic low-grade inflammation may contribute to elevated serum Cu and decreased serum Zn concentrations in the elderly, and may represent an important confounder of the relationship between the serum trace elements and mortality in this population.	24901093
Acute inflammation	Altered Intercellular Communication	Laparoscopic surgery may decrease the risk of postoperative abdominal adhesion compared with open surgery by suppressing early postoperative inflammation.	24901144
Inflammation, Stomach Carcinoma, Infection caused by Helicobacter pylori	Altered Intercellular Communication	As chronic inflammation of the gastric mucosa is a consequence of Helicobacter pylori infection, we investigated the role of genetic polymorphisms and expression of genes involved in the NLR signalling pathway in H. pylori infection and related gastric cancer (GC).	24901306
Choroiditis	Altered Intercellular Communication	Thicker CT 1 week postoperatively after SBS may most likely be induced by scleral buckle reduced blood flow and increased haemostasis in the choroidal circulation and by scleral and choroidal inflammation after cryopexy versus laser photocoagulation after SBS versus PPV.	24901425
Inflammation	Altered Intercellular Communication	Circulating levels of IL-18, and other biochemical markers are parameters of inflammation and were measured in all three groups.	24901579
Inflammation, Calcinosis	Altered Intercellular Communication	Calcification and inflammation are among the important cases of exudative age-related macular degeneration (E-ARMD).	24901855
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	OPN may play a role in the neutrophilic inflammation and in the pathogenesis of emphysema.	24902063
Inflammation, Atrophic	Altered Intercellular Communication	Chronic inflammation was present only in complete atrophy.	24902359
Inflammation, Atrophic	Altered Intercellular Communication	Chronic inflammation may be a secondary phenomenon seen only in complete atrophy.	24902359
Weight decreased	Altered Intercellular Communication	Along with weight loss itself, changes in gut hormone profiles after surgery play an important role in the amelioration of glycemic control.	24902653
Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	While the specific role of PMN in systemic lupus erythematosus (SLE) and autoimmunity is still unclear, their importance in chronic inflammation is gaining more attention.	24902963
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Recently, PG and SS have been included among the autoinflammatory diseases, which are characterized by recurrent episodes of sterile inflammation, without circulating autoantibodies and autoreactive T cells.	24903614
Tissue damage, Inflammation	Altered Intercellular Communication	Fas/Fas ligand and CD40/CD40 ligand systems were over-expressed in PG (P = 00001 for Fas, P = 0009 for Fas ligand, P = 0012 for CD40, P = 00001 for CD40 ligand), contributing to tissue damage and inflammation, while their role seems to be less significant in SS.	24903614
Inflammation, Ischemic stroke	Altered Intercellular Communication	The changes of bilirubin and liver enzymes during ischemic stroke reflect two phenomena, which are both related to IV: 1) inflammation, with consequent increment of CRP, leukocytes and gGT, and decrease of haemoglobin and unconjugated bilirubin and 2) an unknown signal, independent from inflammation, leading to increasing GOT and GPT levels.	24903748
Hyperlipidemia, Inflammation, Diabetes Mellitus, Heart Diseases, Hypertension, CTCAE	Altered Intercellular Communication	Hypertension, hyperlipidemia, diabetes, cardiac diseases, inflammation, and smoking were recorded.	24904181
Non-alcoholic Fatty Liver Disease, Arteritis	Altered Intercellular Communication	Association between nonalcoholic fatty liver disease and carotid artery inflammation evaluated by 18F-fluorodeoxyglucose positron emission tomography.	24904182
Non-alcoholic Fatty Liver Disease, Arteritis	Altered Intercellular Communication	We assessed the association between nonalcoholic fatty liver disease (NAFLD) and carotid artery inflammation measured by (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography.	24904182
Inflammation, Haiti	Altered Intercellular Communication	Higher nBsAb levels were found to be associated with decreased inflammation in HT patients.	24905062
Inflammation, Coronary Artery Disease, Endothelial dysfunction, Diabetes Mellitus	Altered Intercellular Communication	Orosomucoid secretion levels by epicardial adipose tissue as possible indicator of endothelial dysfunction in diabetes mellitus or inflammation in coronary artery disease.	24905138
Inflammation, Fibrosis Assessment, Atrophic	Altered Intercellular Communication	The glands were routinely processed and semi-quantitatively analyzed for inflammation, acinar atrophy, fibrosis, and adipocyte infiltration.	24905142
Inflammation, Fibrosis Assessment, Atrophic	Altered Intercellular Communication	Acinar atrophy and fibrosis were negatively correlated with the parenchymal innervation and positively related to diffuse inflammation.	24905142
Inflammation, Endothelium, Psoriasis, Atherosclerosis	Altered Intercellular Communication	Systemic inflammation and imbalance between endothelial injury and repair in patients with psoriasis are associated with preclinical atherosclerosis.	24906366
Valvular regurgitation, Inflammation, Endothelium, Atherosclerosis	Altered Intercellular Communication	Systemic inflammation and imbalance between endothelial injury and repair, the latter referred to as vascular incompetence, are associated with atherosclerosis and cardiovascular risk.	24906366
Inflammation, Psoriasis, Carotid Intima-Media Thickness, Metabolic Syndrome X, Valvular regurgitation	Altered Intercellular Communication	We investigated whether, in psoriasis, inflammation and vascular incompetence are associated with carotid intima-media thickness (cIMT) irrespective of metabolic syndrome and other established cardiovascular risk factors.	24906366
Valvular regurgitation, Inflammation, Psoriasis, Atherosclerosis	Altered Intercellular Communication	Patients with psoriasis have an increased burden of cardiovascular risk, including inflammation, vascular incompetence and early atherosclerosis.	24906366
HD Term Type, Inflammation	Altered Intercellular Communication	The present study indicates that serum CRP and sICAM-1, as two CVD risk factors, increase in HD patients with PEW as compared to those without PEW and these increases occur in HD patients with PEW type IIa and IIb who have inflammation.	24906424
Inflammation, Edema	Altered Intercellular Communication	after the stage compromised by acute oedema and inflammation.	24906703
Sarcoidosis, Lymphoid hyperplasia, Lymphoma, Orbital Pseudotumor	Altered Intercellular Communication	The most common diagnoses included idiopathic orbital inflammation (IOI; n = 29; 30%), sarcoidosis (n = 19; 20%), prolapsed LG (n = 15; 15%), lymphoma (n = 11; 11%), lymphoid hyperplasia (n = 8; 8%), and dacryops (n = 5; 5%).	24907059
Pain Distress Question, Inflammation, Blepharoptosis	Altered Intercellular Communication	Inflammatory conditions were more likely in younger patients (P<0.05) and in those with pain (P<0.001) and mechanical blepharoptosis (P<0.01) at presentation, whereas lymphoma was more common in older patients (P<0.001) without active signs of inflammation at presentation.	24907059
Pain Distress Question, Inflammation, Blepharoptosis	Altered Intercellular Communication	Inflammatory conditions were more likely in younger patients (P<0.05) and in those with pain (P<0.001) and mechanical blepharoptosis (P<0.01) at presentation, whereas lymphoma was more common in older patients (P<0.001) without active signs of inflammation at presentation.	24907059
Inflammation, Macular retinal edema	Altered Intercellular Communication	Dexamethasone intravitreal implant in the treatment of persistent uveitic macular edema in the absence of active inflammation.	24907061
Adenocarcinoma, Inflammation, Mesothelioma	Altered Intercellular Communication	The definitive diagnoses were adenocarcinoma (n = 10), mesothelioma (n = 2) and chronic inflammation (n = 3).	24907385
Inflammation, Pain Distress Question	Altered Intercellular Communication	Inflammation and inflammatory control in interstitial cystitis/bladder pain syndrome: Associations with painful symptoms.	24907404
Inflammation, Genitourinary pain, Sex Behavior	Altered Intercellular Communication	In IC/BPS patients, inflammation after TLR-4 stimulation was associated with multiple symptoms, including genitourinary pain (P=.010), sexual pain (P=.002), and marginally with urinary symptoms (P=.068).	24907404
Inflammatory abnormality of the eye	Altered Intercellular Communication	Drug-related adverse events were reported by 13 (41%) of 32 patients; they included ocular inflammation in 11 patients (7 mild, 4 moderate in severity).	24907435
Inflammatory abnormality of the eye	Altered Intercellular Communication	A single injection of 1.0 or 2.0 mg MP0112 resulted in mean decreases in retinal thickness and leakage area despite ocular inflammation.	24907435
Inflammation	Altered Intercellular Communication	Flow cytometry-based analysis by Sysmex-UF1000i(r) is an alternative method in the assessment of periodontal inflammation.	24907666
Inflammation	Altered Intercellular Communication	We explored the value of flow cytometry of saliva in patients with periodontal inflammation.	24907666
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Our results support the hypothesis that air pollution increases systemic inflammation especially in susceptible populations which may aggravate atherosclerotic diseases and induce multi-organ damage.	24907704
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation is a hallmark of Alzheimer's disease (AD).	24907904
hydrocortisone, Inflammation, Data types - Address	Altered Intercellular Communication	Despite inflammation being a hallmark in AD and previous reports showing that the NLR can discriminate HC from AD patients, our results suggest that the sensitivity of the NLR itself is not robust enough for diagnostic utility.	24907904
Inflammation, Respiratory Hypersensitivity	Altered Intercellular Communication	Previously, we showed that, in ovalbumin (OVA)-sensitized and -challenged mice with allergic airway inflammation, rhinovirus (RV) infection increases type 2 cytokine production from alternatively-activated (M2) airway macrophages, enhancing eosinophilic inflammation and airways hyperresponsiveness.	24907978
Airway structure, neutrophilic, Inflammation	Altered Intercellular Communication	In contrast to OVA-treated wild-type mice with both neutrophilic and eosinophilic airway inflammation, OVA-treated IL-4R KO mice showed increased neutrophilic inflammation with few eosinophils in the airways.	24907978
Inflammation, Residual volume	Altered Intercellular Communication	RV infection of OVA-treated IL-4R KO mice further increased neutrophilic inflammation.	24907978
Airway structure, Allergic	Altered Intercellular Communication	OVA-treated IL-4R KO mice show neutrophilic airway inflammation constituting a model of allergic, type 1 cytokine-driven neutrophilic asthma.	24907978
Inflammation, Residual volume	Altered Intercellular Communication	In the absence of IL-4/IL-13 signaling, RV infection of OVA-treated mice increased type 1 cytokine and IL-17A production from conventionally-activated macrophages, augmenting neutrophilic rather than eosinophilic inflammation.	24907978
Residual volume	Altered Intercellular Communication	In mice with allergic airways inflammation, IL-4R signaling determines macrophage activation state and the response to subsequent RV infection.	24907978
Inflammation, Carcinoma of bladder	Altered Intercellular Communication	Of 12 (18)F-FDG-avid cases, 10 cases were confirmed to be primary bladder carcinoma, 2 false-positive cases were inflammation.	24908368
Inflammation, Psoriasis, Chronic disease	Altered Intercellular Communication	Psoriasis is a common chronic disease, mediated by type 1 and 17 helper T cell-driven inflammation.	24909271
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Literature on the relationship between depression and C-reactive protein (CRP), a biomarker of systematic inflammation, remains inconsistent.	24909972
Inflammation, Data types - Address	Altered Intercellular Communication	This study supports the role of infection/inflammation in the etiopathogenesis of AD.	24910016
Inflammation, Cytomegalovirus, Perforation (observation)	Altered Intercellular Communication	Pathologic examination of the resected appendiceal tissue demonstrated inflammation with perforation and cytopathic changes typical of CMV that were positive for CMV by immunostain.	24910267
Inflammation	Altered Intercellular Communication	Differences in chronic intragraft inflammation between positive crossmatch and ABO-incompatible kidney transplantation.	24911035
Inflammation, Renal glomerular disease	Altered Intercellular Communication	At 5 years, renal function was similar in ABOiKTx and conventional KTx, and both were higher than that of +XMKTx, which had higher rates of inflammation and chronic glomerulopathy on both 1- and 5-year biopsies.	24911035
Inflammation, graft loss	Altered Intercellular Communication	These data suggest that +XMKTxs have high rates of chronic inflammation at 1 and 5 years after transplantation, which may explain the higher rates of graft loss and lower renal function compared with other factors such as anti-donor antibody or intragraft complement deposition.	24911035
Autoimmune Diseases, Orbital Pseudotumor	Altered Intercellular Communication	An orbital biopsy showed a fibrotic idiopathic orbital inflammation (IOI) with, on immunohistochemical staining, an increased number of IgG4-positive plasma cells scored as >200 per high-power field, with IgG4/IgG ratio >0.50, indicating orbital IgG4 related autoimmune disease.	24911364
Inflammation, Hyperplasia	Altered Intercellular Communication	Microscopic evaluation of the excised lesion disclosed a pseudoadenomatous (pseudoglandular) hyperplasia of the conjunctival epithelium with myriad goblet cells and accompanying chronic inflammation.	24911539
Cessation of life, Inflammation, Blood Clot	Altered Intercellular Communication	The TIDE (Thrombus and Inflammation in sudden DEath) study.	24912925
Inflammation, Obesity	Altered Intercellular Communication	Telomere shortening is physiologically associated with ageing but it may be influenced by oxidative stress and chronic inflammation, linked to obesity.	24913239
Rheumatoid Arthritis, Pneumonitis	Altered Intercellular Communication	Rheumatoid arthritis-associated interstitial lung disease: lung inflammation evaluated with high resolution computed tomography scan is correlated to rheumatoid arthritis disease activity.	24913966
Inflammation, Refractory anemias, Fibrosis Assessment, Rheumatoid Factor, Rheumatoid Arthritis, Lung Diseases, Interstitial	Altered Intercellular Communication	To describe the association between rheumatoid arthritis disease activity (RA) and interstitial lung damage (inflammation and fibrosis), in a group of patients with rheumatoid arthritis-associated interstitial lung disease (RA-ILD).	24913966
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	Interstitial lung inflammation and fibrosis were determined by Kazerooni scale.	24913966
Pneumonitis, Disease	Altered Intercellular Communication	These results suggest a positive association between RA disease activity and lung inflammation in RA-ILD.	24913966
Communicable Diseases, Inflammation	Altered Intercellular Communication	Gut colonization, inflammation and pro-carcinogenic potential were assessed in a chronic infection model using CEABAC10 transgenic mice.	24914378
Malignant tumor of colon, Communicable Diseases, Epithelial Damage, Colitis	Altered Intercellular Communication	In addition, in vivo experiments using a chronic infection model of CEACAM6 expressing mice showed that B2 E. coli strain 11G5 isolated from colon cancer is able to highly persist in the gut, and to induce colon inflammation, epithelial damages and cell proliferation.	24914378
Malignant tumor of colon, Inflammation, Carcinogenesis	Altered Intercellular Communication	In conclusion, these data bring new insights into the ability of E. coli isolated from patients with colon cancer to establish persistent colonization, exacerbate inflammation and trigger carcinogenesis.	24914378
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histologic findings were consistent with a chronic inflammation with fibrosis.	24914690
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Endocrine System Diseases, Generalized amyotrophy	Altered Intercellular Communication	Skeletal muscle wasting commonly occurs in patients with chronic obstructive pulmonary disease (COPD) and has been associated with the presence of systemic inflammation and endocrinological disturbance.	24915195
Inflammation, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	Studies on inflammation biomarkers in serum and in exhaled breath condensate (EBC) in obstructive sleep apnea (OSA) have shown conflicting results.	24915890
Inflammation, Osage language	Altered Intercellular Communication	In mildly obese OSA patients, EBC biomarkers of inflammation or oxidative stress were normal at baseline and remained unchanged 3 months after UAS or CPAP.	24915890
Inflammatory abnormality of the eye	Altered Intercellular Communication	CD44 and RHAMM hyaluronan receptors in human ocular surface inflammation.	24916930
Inflammatory abnormality of the eye	Altered Intercellular Communication	The purpose of this research was to determine if CD44 and RHAMM are implicated in human ocular surface inflammation.	24916930
Inflammatory abnormality of the eye	Altered Intercellular Communication	Upper tarsal conjunctival epithelial samples from patients with active ocular surface inflammation (n = 17) and healthy controls (n = 14) were recovered by brush cytology.	24916930
Inflammation, Disease	Altered Intercellular Communication	Patients were evaluated by an ophthalmologist and classified in different groups according to the etiology (immune atopic diseases or immune non-atopic diseases) and inflammation intensity (mild/moderate or severe).	24916930
Inflammation, Disease	Altered Intercellular Communication	In immune atopic diseases, higher levels of CD44 and RHAMM mRNAs were present, reaching a 300 % increase for RHAMM in severe inflammation (p < 0.001).	24916930
Inflammatory abnormality of the eye	Altered Intercellular Communication	RHAMM may be implicated in severe ocular surface inflammation affecting the upper tarsal conjunctiva.	24916930
Inflammation	Altered Intercellular Communication	Histology showed mild chronic inflammation of the mucosa, but no ulceration.	24916983
Pleural Effusion, CTCAE, Inflammation, Hypertrophy	Altered Intercellular Communication	In February 2011, however, enlargement of the tumor with inflammation and right pleural effusion was found.	24917412
Inflammation, Hemorrhage, Neoplasms, Necrosis	Altered Intercellular Communication	Granulation due to old inflammation, precipitation of cholesterin crystals, hemorrhages, and necrosis were noted in the tumor.	24917412
Inflammation, Undifferentiated Connective Tissue Diseases	Altered Intercellular Communication	Our data suggest that the presence of inflammation and autoantibodies provoke endothelial cell activation and/or injury in UCTD patients.	24917564
Interstitial inflammation, Pneumonia	Altered Intercellular Communication	Radiological changes associated with both acute pneumonia and acute interstitial inflammation were observed in early H7N9 avian influenza cases.	24917607
Inflammation, Sleep Apnea, Obstructive, Dyslipidemias, Obesity	Altered Intercellular Communication	Obesity and obstructive sleep apnea tend to coexist and are associated with inflammation, insulin resistance, dyslipidemia, and high blood pressure, but their causal relation to these abnormalities is unclear.	24918371
Inflammation, Sleep Apnea, Obstructive, Hypertension, CTCAE	Altered Intercellular Communication	Obstructive sleep apnea is associated with hypertension, inflammation, and increased cardiovascular risk.	24918372
Inflammation, Pruritus	Altered Intercellular Communication	Instead, anti-inflammatory agents are used to reduce inflammation and therefore improve associated itch.	24918564
Inflammation	Altered Intercellular Communication	This supports the hypothesis that differences in growth rates and expression levels of complement, inflammation and apoptosis genes may result from population-specific, hereditary SNP variations in mtDNA.	24919117
Inflammation	Altered Intercellular Communication	The basic mechanism in obesity-related complications is chronic inflammation and increased oxidative stress.	24920129
Inflammation, Collagen Diseases, diabetic, Neuralgia, Eczema	Altered Intercellular Communication	Cocculus hirsutus (L.) Diels (Menispermaceae) is used in Indian folk system of alternative medicine for rheumatism, eczema, diabetics, inflammation, and neuralgia.	24920232
Inflammation, Endophthalmitis, CTCAE	Altered Intercellular Communication	Both patients had received other vascular endothelial growth factor inhibitors prior to aflibercept administration without signs of inflammation and both cases had sterile endophthalmitis.	24920511
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Despite a number of studies on biomarkers in chronic obstructive pulmonary disease (COPD), only a few disease-related markers have been identified, yet we still have no satisfactory markers specific to innate immune system and neutrophil activation, which is essential in airway inflammation in COPD.	24920892
Airway structure, ARCN1 gene	Altered Intercellular Communication	Recent biological studies indicated that lipocalins (LCNs) might be involved in airway inflammation and innate immunity; however, results from available studies on the association of LCNs with COPD are not consistent.	24920892
Asthma, Overweight, Obesity	Altered Intercellular Communication	Whether allergic airway inflammation mediates the association between overweight or obesity and childhood asthma is unknown.	24922361
Intraocular inflammation	Altered Intercellular Communication	Combined albendazole and corticosteroid therapy may reduce intraocular inflammation and recurrence.	24922534
Inflammation, Hemorrhage, Fibrosis Assessment, Congestion	Altered Intercellular Communication	Evaluation of each specimen was based on the presence of congestion, inflammation, hemorrhage and fibrosis.	24922681
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Several studies have shown that serum bilirubin has a protective effect against cardiovascular disease and that inflammation plays an important role in its pathogenesis.	24923275
Gastric Adenocarcinoma, Primary malignant neoplasm, Inappropriate ADH Syndrome	Altered Intercellular Communication	To our knowledge, this is the first report of an antidiuretic hormone-secreting advanced gastric adenocarcinoma associated with the syndrome of inappropriate antidiuretic hormone, showing cancer cells immunostained for the antidiuretic hormone.	24923603
Primary malignant neoplasm, Stomach Carcinoma	Altered Intercellular Communication	Although a strong relationship between gastric cancer and the syndrome of inappropriate antidiuretic hormone remains to be established, we suggest that gastric cancer could be included as a differential diagnosis of cancer that is associated with the syndrome of antidiuretic hormone.	24923603
Inflammation, Hypertension, CTCAE, GDC Comorbidity Terminology, Diabetes Mellitus	Altered Intercellular Communication	Inflammation in response to comorbid conditions, such as hypertension and diabetes, may play a proportionally larger role in HFPEF as compared to HF with reduced ejection fraction (HFREF).	24923671
Inflammation	Altered Intercellular Communication	Inflammation mediated through TNFa and its receptors, TNFR1 and TNFR2, may represent an important component of a comorbidity-induced inflammatory response that partially drives the pathophysiology of HFPEF.	24923671
Communicable Diseases, Vertical Talus, Inflammation	Altered Intercellular Communication	The causes of CVT may be categorized into three main groups: hypercoagulable states, conditions causing blood flow disturbances, and all causes of inflammation or infection.	24923843
Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	Malnutrition, inflammation, and atherosclerosis syndrome could be partially responsible for the observed association.	24923997
Chronic infectious disease, Allergic	Altered Intercellular Communication	Histopathology revealed abnormal lymphoplasmacytic inflammation of the mucosa in 4 of 5 biopsies of DS patients, consistent with chronic infection, allergic disease, or immune dysregulation.	24924273
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Sedentary time and markers of inflammation in people with newly diagnosed type 2 diabetes.	24925122
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	We investigated whether objectively measured sedentary time was associated with markers of inflammation in adults with newly diagnosed type 2 diabetes.	24925122
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Interventions to reduce sedentary time may help to reduce inflammation in women with type 2 diabetes.	24925122
Vasculitis, Dental Plaque, Cardiovascular Diseases	Altered Intercellular Communication	The effects of the mediterranean diet on biomarkers of vascular wall inflammation and plaque vulnerability in subjects with high risk for cardiovascular disease.	24925270
Inflammation, Lupus Nephritis, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Lupus nephritis is a manifestation of SLE resulting from glomerular immune complex deposition and inflammation.	24925725
Intraocular inflammation, Ocular syphilis	Altered Intercellular Communication	British Ocular Syphilis Study (BOSS): 2-year national surveillance study of intraocular inflammation secondary to ocular syphilis.	24925878
Intraocular inflammation	Altered Intercellular Communication	Case definition was any adult presenting with intraocular inflammation in ES.	24925878
Communicable Diseases, Inflammation, Obesity	Altered Intercellular Communication	Although animal studies suggest that adenovirus 36 (Ad36) infection is linked to obesity and systemic inflammation, human data are scant and equivocal.	24926952
Inflammation	Altered Intercellular Communication	In children, our data suggest that Ad36(+) may be associated with biomarkers implicated in inflammation but not with greater levels of fat mass.	24926952
Gingivitis	Altered Intercellular Communication	Time course analysis of brachial artery flow mediated dilatation in subjects with gingival inflammation.	24927022
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Nevertheless, possible relationship between gingival inflammation and endothelial dysfunction observed over this temporal threshold remains still unexplored.	24927022
Ultraviolet B radiation, Malignant neoplasm of skin	Altered Intercellular Communication	Ultraviolet B (UVB) irradiation may cause oxidative stress- and inflammation-dependent skin cancer and premature aging.	24927233
Hepatitis	Altered Intercellular Communication	These findings suggest that IGT and DM may be causally implicated with liver inflammation process.	24927611
Inflammation, Edema	Altered Intercellular Communication	Antisecretory factor (AF) and derivates thereof counteract brain edema and inflammation, and normalize ICP dynamics.	24928077
Refractory anemias, Rheumatoid Arthritis, Inflammation, Cardiovascular morbidity	Altered Intercellular Communication	Rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity and mortality attributed to traditional cardiovascular risk factors and/or the chronic systemic inflammation.	24928345
Inflammation, Metabolic Diseases	Altered Intercellular Communication	In recent years links among vitamin D deficiency, inflammation and cardio-metabolic disease were proposed.	24928661
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Synovial fluid levels of adipokines in osteoarthritis: Association with local factors of inflammation and cartilage maintenance.	24928914
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	For this purpose, we investigated in patients with OA the relationships between the joint levels of leptin, adiponectin and resistin and those of factors involved in inflammation and cartilage maintenance.	24928914
Autoimmune Diseases, Inflammation, Primary malignant neoplasm, Bacterial Infections	Altered Intercellular Communication	They were identified originally in cancer patients and have since been reported to occur also in chronic inflammation, autoimmunity, and even bacterial infections.	24929004
Stomach Carcinoma	Altered Intercellular Communication	Gastric cancer (GC) is a progressive process initiated by Helicobacter pylori-induced inflammation.	24929142
HIV, Chronic inflammation, Depression, CTCAE	Altered Intercellular Communication	Human Immunodeficiency Virus (HIV) infection has been frequently associated with chronic inflammation as well as depression.	24929193
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Further prospective study to confirm the role of inflammation in depression among HIV-positive people is warranted.	24929193
Inflammation, Atherosclerosis	Altered Intercellular Communication	Fractalkine (CX3CL1) is a chemokine associated with atherosclerosis and inflammation.	24930044
Fibrosis, Liver, Inflammation	Altered Intercellular Communication	All keratins were overexpressed in subjects with moderate vs. minimal inflammation, while K7, K8 and K18 were upregulated in patients with advanced liver fibrosis.	24930437
Parkinson Disease, Inflammation	Altered Intercellular Communication	Moderate-intensity interval training increases serum brain-derived neurotrophic factor level and decreases inflammation in Parkinson's disease patients.	24930517
Parkinson Disease, Inflammation	Altered Intercellular Communication	We have concluded that the improvement of health status of the Parkinson's disease patients after training could be related to the increase of serum BDNF level caused by the attenuated inflammation in those patients.	24930517
Renal Insufficiency, Inflammation, Fever, CTCAE, Polycystic Kidney, Autosomal Dominant, Pleural Effusion, CTCAE	Altered Intercellular Communication	A 64-year-old Japanese man with renal dysfunction caused by autosomal dominant polycystic kidney disease (ADPKD) was admitted to our hospital for evaluation of right back pain, fever, inflammation, and pleural effusion.	24930657
Pleural Effusion, CTCAE, Inflammation, Pain Distress Question	Altered Intercellular Communication	After drainage, the symptoms of inflammation, right back pain and right pleural effusion subsided.	24930657
Pleural Effusion, CTCAE, Inflammation, Communicable Diseases	Altered Intercellular Communication	The pleural effusion was due to the propagation of inflammation from the cyst infection.	24930657
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	Chronic rhinosinusitis with nasal polyps is generally characterized by local Th2 inflammation and is categorized into two subtypes in Japan: eosinophilic chronic rhinosinusitis (similar to chronic rhinosinusitis with nasal polyps in western countries) and non-eosinophilic chronic rhinosinusitis (characterized by Th1-dominant inflammation).	24931597
Inflammation, Basal-Like Breast Carcinoma	Altered Intercellular Communication	Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation.	24931643
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Inflammation is an important component of various cancers and its inflammatory cells and mediators have been shown to have prognostic potential.	24931643
Inflammation, Atherosclerosis	Altered Intercellular Communication	An abnormal profile in serum adipokines observed in AMI is related to systemic inflammation and the degree of atherosclerosis independently of glucose metabolism disturbances and heralds major adverse cardiovascular event occurrence in long-term observation.	24933198
Inflammation, Electrocardiogram: myocardial infarction (finding), Cardiovascular Diseases	Altered Intercellular Communication	Chemokines, including RANTES, play a crucial role in the processes of inflammation during cardiovascular disorders, including myocardial infarction, disease progression and complications.	24934326
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Oxidative stress and inflammation are two key mechanisms suggested to be involved in the pathogenesis of Alzheimer's disease (AD).	24934544
Inflammation, Prostate, Benign prostatic hypertrophy	Altered Intercellular Communication	Benign prostatic hyperplasia (both with and without inflammation) was the commonest prostatic lesion and accounted for 80.3% of all cases and 97.6% of all benign cases.	24935366
Osteomyelitis, Inflammation	Altered Intercellular Communication	Although the affected patients showed all clinical signs of acute inflammation, expression levels in acute and secondary chronic osteomyelitis in the jaws did not reveal statistically significant differences compared with healthy bone samples.	24935813
Pain Distress Question, Primary malignant neoplasm, Phlebitis	Altered Intercellular Communication	During chemotherapy of cancer patients, vein inflammation may develop which may lead to pain and difficulty in blood sampling.	24936574
Cancer-related fatigue, Inflammation, Low muscle mass, Obesity, Visceral	Altered Intercellular Communication	Previous studies have shown that low cardiorespiratory fitness (CRF), visceral obesity and low muscle mass may share pathophysiological mechanisms, such as insulin resistance and chronic inflammation.	24937121
Inflammation, Injury of liver	Altered Intercellular Communication	IL-1alpha may have important role as marker of both inflammation and hepatic injury, particularly in the course of hepatitis B.	24937930
Hepatitis	Altered Intercellular Communication	IL-1alpha was significantly elevated in inflammatory conditions of pronounced activity (PCR positive hepatitis).	24937930
Ulcerative Colitis, Colitis	Altered Intercellular Communication	The association between pulmonary function impairment and colon inflammation in ulcerative colitis patients: A scientific basis for exterior-interior correlation between lung and large intestine.	24938448
Inflammation, Rupture	Altered Intercellular Communication	The results suggest that macrophage-mediated inflammation is a key biological pathway for IA rupture.	24938844
Inflammation, Necrosis	Altered Intercellular Communication	As expected, the presence of valve necrosis and acute inflammation decreased with an increase in time with respect to symptomatic onset.	24939149
Streptococcal Infections, Have Autoimmune or Inflammatory Condition, Bacterial Endocarditis	Altered Intercellular Communication	Histologic findings that mimic autoimmune inflammation are frequent in infective endocarditis and associated with streptococcal infection.	24939149
Inflammation, Small vessel vasculitis, Structure of vasa vasorum	Altered Intercellular Communication	There were no significant differences in the frequencies of positive TAB for classic transmural inflammation (28% vs 18.2%) or for periadventitial small vessel vasculitis and/or vasa vasorum vasculitis (6% vs 14.5%) between the two groups.	24939678
Necrotizing granulomatous inflammation, Giant Cell Arteritis, GCA gene	Altered Intercellular Communication	This was confirmed by targeted temporal artery biopsy, which showed chronic granulomatous inflammation typical of giant cell arteritis (GCA).	24940569
Tracheobronchitis, Ulceration, CTCAE	Altered Intercellular Communication	Simple tracheobronchitis was considered when the bronchoscopy report described mucosal inflammation and mucus secretions and invasive tracheobronchitis when ulceration and pseudomembrane formation was reported.	24940892
Refractory anemias, Rheumatoid Arthritis, Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	The elevated risk of ischaemic heart disease in patients with rheumatoid arthritis (RA) has been linked to inflammation and disease severity.	24941916
Communicable Diseases, Inflammation, Biliary Dyskinesia	Altered Intercellular Communication	Biliary dyskinesia, inflammation or infection of the gallbladder was reported for 20 women (5%) and of those 13 had undergone gallbladder surgery.	24942262
Vasculitis, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is often associated with chronic vascular inflammation.	24942794
Malignant neoplasm of urinary bladder, Inflammation, Hyperplasia	Altered Intercellular Communication	Immunohistochemical staining for periplakin was shown to be significantly lower in bladder cancer tissues compared to non-cancerous tissues including inflammation,hyperplasia and normal urothelium.	24942859
Inflammation	Altered Intercellular Communication	The most common BAL cellular pattern was mixed inflammation with moderate lymphocytic and mild neutrophilic alveolitis.	24942974
Inflammation	Altered Intercellular Communication	Mixed inflammation with moderate lymphocytic and mild neutrophilic alveolitis is the most common BAL cellular pattern in patients with mAB-ILD.	24942974
Inflammation, Inflammatory Myofibroblastic Tumor	Altered Intercellular Communication	An inflammatory pseudotumor is a rare benign disease presenting with non-specific chronic inflammation, and reported occurrences involving the skull base are relatively rare.	24943507
Granuloma, Inflammation	Altered Intercellular Communication	Histologically, the oral pulse granuloma consists of multinucleated foreign body type giant cells, hyaline rings and chronic inflammation tissue.	24943674
Tolosa-Hunt Syndrome, Inflammation, Methylated spirit	Altered Intercellular Communication	Tolosa-Hunt syndrome (THS) is described as painful ophtalmoplegia caused by nonspesific inflammation of cavernous sinus or superior orbital fissure, which is response to steroid theraphy.	24943858
Vascular Diseases	Altered Intercellular Communication	This study aimed to observe the expression of inflammation-related factors in elderly T2DM patients with or without macrovascular disease (MVD).	24943964
Inflammation, Damage, Weight decreased	Altered Intercellular Communication	Magnesium deficiency significantly increased cisplatin-associated weight loss and markers of renal damage (plasma blood urea nitrogen and creatinine), histological changes, inflammation, and renal cell apoptosis and modulated signaling pathways (e.g., ERK1/2, p53, and STAT3).	24944268
Inflammation, Pancreatitis, Biliary calculi, Biliary Tract Neoplasm, Pancreatic Neoplasm	Altered Intercellular Communication	By analyzing the incidence of biliary stone and inflammation, pancreatitis, biliary duct tumors and pancreatic tumors between normal and abnormal types, significant differences existed.	24944495
Chronic folliculitis, Perifolliculitis	Altered Intercellular Communication	Histopathologic examination revealed perifollicular chronic and granulomatous inflammation, consistent with chronic folliculitis.	24945647
Inflammation, Pain, Postoperative	Altered Intercellular Communication	Antibiotics remove the local flora and reduce inflammation and thus may reduce postoperative pain after tonsillectomy.	24946226
Inflammation, Periodontitis, SMYD1 gene, Coronary heart disease	Altered Intercellular Communication	In coronary heart disease patients with periodontitis, BOP is strongly associated with systemic CRP levels; this association possibly reflects the potential significance of the local periodontal inflammatory burden for systemic inflammation.	24946826
Rupture, Hemorrhage, Inflammation, Blood Clot, Fibrous	Altered Intercellular Communication	Based on the presence and extent of histological features including haemorrhage, thrombus, fibrous tissue, lipid core, inflammation, neovascularity, foam cells, and cap rupture, 39 plaques were graded as predominantly stable, while 87 were predominantly unstable.	24947079
Communicable Diseases, Inflammation	Altered Intercellular Communication	Loss of cartilage will increase endplate permeability, facilitating endplate inflammation and disc infection.	24947181
Inflammation, Ovarian Cysts, Transcription Initiation	Altered Intercellular Communication	Given that chronic inflammation plays a central role in cancer initiation and progression, we selected and tested 15 cancer-related cytokines and growth factors in 38 ovarian cyst fluid samples.	24947406
Inflammation, Neoplasms, Ulcerative Colitis	Altered Intercellular Communication	The lack of correlation between well-known IBD-associated SNPs and UC-neoplasia demonstrated in this study suggests that the development of neoplasia in patients with UC is associated with genetic determinants other than those that predispose to inflammation or results from posttranslational modifications or epigenetic factors rather than germline polymorphisms.	24947639
Inflammation, Stomatitis, Denture	Altered Intercellular Communication	Denture stomatitis, inflammation and redness beneath a denture, affects nearly half of all denture wearers.	24947908
Inflammation, Hemorrhagic, Pain Distress Question	Altered Intercellular Communication	Main outcome measures were the incision inflammation rate, skin preparation time, presence of shaving-induced macroscopic haemorrhagic spots, verbal rating scale (VRS) pain score and satisfaction.	24948414
Inflammation, Dyslipidemias, Osteoporosis, Cardiovascular Diseases	Altered Intercellular Communication	The presence of common risk factors suggests that there is a relationship between osteoporosis and cardiovascular disease, possibly via dyslipidemia and inflammation.	24949440
Inflammation	Altered Intercellular Communication	A biopsy was taken and on histology, transmural granulomatous inflammation of numerous eosinophils, lymphocytes, plasmocytes and giant cells was seen.	24950873
Prostate carcinoma, prostatitis	Altered Intercellular Communication	Pentraxin 3: a novel biomarker for predicting progression from prostatic inflammation to prostate cancer.	24950910
Prostate carcinoma	Altered Intercellular Communication	Furthermore, we evaluated PTX3 serum concentrations in an independent set of patients with biopsy-proven inflammation/BPH (n = 61) and prostate cancer (n = 56).	24950910
Prostate, Prostate carcinoma	Altered Intercellular Communication	We found reduced PTX3 tissue expression in patients with prostatic inflammation/BPH compared with patients who developed prostate cancer.	24950910
Prostate carcinoma	Altered Intercellular Communication	PTX3 serum levels were also higher in patients with prostate cancer than in patients with inflammation/BPH.	24950910
Liver carcinoma	Altered Intercellular Communication	Usefulness of a new inflammation-based scoring system for prognostication of patients with hepatocellular carcinoma after hepatectomy.	24950991
Inflammation, Malnutrition, Communicable Diseases, malignant disease, Liver damage, Traumatic injury	Altered Intercellular Communication	Its serum level is reduced in many clinical conditions, such as liver damage, inflammation, injury, infection, malnutrition, and malignant disease.	24951323
Inflammation, Hemorrhage, Pain Distress Question	Altered Intercellular Communication	In addition to rapid bleeding control, the dressing causes minimal inflammation and pain and allows patients to quickly return to normal activities.	24952410
Cancer of Nasopharynx	Altered Intercellular Communication	Relationships between genetic polymorphisms in inflammation-related factor gene and the pathogenesis of nasopharyngeal cancer.	24952889
Inflammation, Hyperplasia, Chronic infectious disease	Altered Intercellular Communication	Pseudoepitheliomatous hyperplasia is a benign condition that may be caused by prolonged inflammation, chronic infection, and/or neoplastic conditions of the mucous membranes or skin.	24953614
Inflammation, Collagen Diseases	Altered Intercellular Communication	To determine the markers of systemic inflammation in soft tissue rheumatic disorders (STRDs).	24953920
Inflammation, Adiposis Dolorosa	Altered Intercellular Communication	Features of subtle systemic inflammation are positive in some cases of soft tissue rheumatism.	24953920
Inflammation, Arthritis, Psoriatic	Altered Intercellular Communication	S-calprotectin (S100A8/S100A9): a potential marker of inflammation in patients with psoriatic arthritis.	24955375
Inflammation, Obesity	Altered Intercellular Communication	Visceral adipose tissue (VAT) is a key contributor to chronic inflammation in obesity.	24955608
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	ALOX 12 may have a critical role in regulation of inflammation in VAT in obesity and T2D.	24955608
Inflammation, Obesity	Altered Intercellular Communication	Selective ALOX 12 inhibitors may constitute a new approach to limit AT inflammation in human obesity.	24955608
Meningism, Inflammation, Edema	Altered Intercellular Communication	During hospitalization the patient's neurological status deteriorated, presenting signs of meningeal irritation along with signs of inflammation and oedema of the right knee.	24955800
Necrotizing granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	Histopathological assessment unexpectedly revealed a chronic granulomatous inflammation compatible with tuberculosis.	24955803
Inflammation, Asthma	Altered Intercellular Communication	Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma.	24955983
Asthma	Altered Intercellular Communication	Such changes may have relevance to treatment-resistant severe asthma, particularly those with neutrophilic airway inflammation, as bacteria might be anticipated to activate the innate immune response, a process that is poorly steroid responsive.	24955983
Airway structure, Asthma, Airway Obstruction	Altered Intercellular Communication	Airway colonisation with potentially pathogenic micro-organisms in asthma is associated with more severe airways obstruction and neutrophilic airway inflammation.	24955983
Inflammation, Whole-Body Irradiation, Traumatic, Blood Coagulation Disorders	Altered Intercellular Communication	Traumatic brain injury (TBI) has a complex pathophysiology that involves coagulopathy and inflammation.	24956150
Inflammation	Altered Intercellular Communication	Life-course-persistent asthma is related to a proposed biomarker of accelerated aging, possibly via systemic eosinophilic inflammation.	24956257
Granulomatous inflammation	Altered Intercellular Communication	Histopathological results confirmed granulomatous inflammation in 38 patients (93%).	24956337
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Insulin resistance and systemic inflammation, but not metabolic syndrome phenotype, predict 9 years mortality in older adults.	24956526
Increased insulin level, Aggressive behavior, Inflammation	Altered Intercellular Communication	Adipokine secretion and AKT/mTOR activation play important roles in obesity-accelerated breast cancer aggressiveness in addition to hyperinsulinemia, estrogen signaling, and inflammation.	24957076
Communicable Diseases, Inflammation	Altered Intercellular Communication	Decreased CFTR expression and/or function lead to impaired airway surface liquid (ASL) volume homeostasis, resulting in accumulation of mucus, reduced clearance of bacteria, and chronic infection and inflammation.	24957904
Sepsis, Inflammation	Altered Intercellular Communication	Redox state of pentraxin 3 as a novel biomarker for resolution of inflammation and survival in sepsis.	24958171
Inflammation, Malignancy-associated membranous nephropathy, Edema	Altered Intercellular Communication	Solid-organ malignancy-associated CSVV was less likely to demonstrate papillary dermal oedema (P = 004), papillary dermal inflammation (P < 0001) and lymphocytes (P < 0001), and more likely to have plasma cells (P = 002).	24958433
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Single blinded pathologist interpretation was performed, with inflammation, fibrosis, neovascularization, foreign body (FB) reaction, and wall thickness assessed semi-quantitatively and scored from 0-3.	24958647
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Varying degrees of inflammation and fibrosis were common features at all times.	24958647
Amyloidosis, Nephrosis, Fibrinoid necrotizing inflammation	Altered Intercellular Communication	ABT improved rheumatoid inflammation and AA amyloidosis, one case showing clinical remission and the other demonstrating incomplete recovery of nephrosis but stable kidney function.	24959698
Fibrinoid necrotizing inflammation	Altered Intercellular Communication	One case showed complete regression of AA amyloid fibrils in serial upper gastrointestinal biopsies, but the other case still had AA amyloid deposits despite ABT-induced normalised rheumatoid inflammation, with polymorphonuclear leukocytes and macrophages infiltrating tissues containing AA amyloid.	24959698
Inflammation	Altered Intercellular Communication	The results do not necessarily reflect Doppler evaluation as being ineffective, but may be caused by DAS28 not being a perfect marker of inflammation.	24960526
Inflammation, Data types - Address	Altered Intercellular Communication	Aggregated amyloid-b (Ab), oxidative stress, and inflammation have pivotal roles in the pathogenesis of AD.	24960578
Periapical bone loss, Inflammation	Altered Intercellular Communication	In patients with periapical lesions and patients after root canal therapy, the concentrations of cytokines did not indicate for the systemic inflammation.	24960621
Chronic Kidney Diseases	Altered Intercellular Communication	Plasma concentrations of IL-6 and TNF-a appear to be more sensitive markers of odontogenic inflammation in CKD patients than CRP.	24960621
Low Back Pain, Inflammation	Altered Intercellular Communication	This produces common low back pain by causing inflammation and sensitization of the peridural membrane and periosteum that forms the boundaries of this compartment.	24961282
Inflammation, Liver Dysfunction	Altered Intercellular Communication	There was an even greater improvement when olive and fish oils were also added with higher incidence of resolution of abnormal liver function tests and reduced inflammation.	24961544
Inflammation	Altered Intercellular Communication	However, MRI may be helpful in showing typical findings including perivascular space inflammation and enhancement.	24962051
Sepsis, Inflammation	Altered Intercellular Communication	Persistent inflammation and T cell exhaustion in severe sepsis in the elderly.	24962182
Sepsis, Inflammation	Altered Intercellular Communication	Although aging is crucial in sepsis, the impact of aging on inflammation and immunosuppression is still unclear.	24962182
Sepsis, Inflammation	Altered Intercellular Communication	Persistent inflammation and T cell exhaustion may be associated with decreased survival in elderly patients and mice after sepsis.	24962182
palladium, Dysautonomia	Altered Intercellular Communication	Our goal is to report the cardiac sympathetic neurotransmission in de novo Brazilian patients with sporadic PD, without clinically defined dysautonomia.	24964109
palladium, Dysautonomia	Altered Intercellular Communication	We concluded that 123I cMIBG has been able to identify cardiac sympathetic neurotransmission disorder in Brazilian de novo PD patients without clinically defined dysautonomia.	24964109
Inflammation, Communicable Diseases, Thoracic Injuries, Pseudoaneurysm, Acute myocardial infarction, Myocardial rupture	Altered Intercellular Communication	Pseudoaneurysm is a very rare and unusual form of myocardial rupture, with complications such as chest trauma, inflammation, acute myocardial infarction, and infection.	24964750
Gingivitis, Periodontitis, Tooth Loss	Altered Intercellular Communication	Salivary cortisol levels in the patients with periodontitis were correlated with worse PI, higher gingival inflammation, and greater tooth loss.	24965061
Inflammation, Hematoma, Sinusitis	Altered Intercellular Communication	Orbital inflammation secondary to sinusitis is common in children, whereas orbital subperiosteal hematoma secondary to sinusitis is extremely rare, with only 11 reported cases, including one case in children.	24965687
Inflammation, Hematoma	Altered Intercellular Communication	Our review of literature shows that sudden onset, afebrile, and few signs of inflammation on blood test in patients with subperiosteal lesion may indicate subperiosteal hematoma.	24965687
Inflammation, Atrophic	Altered Intercellular Communication	Patients with cagA-positive H. pylori could be at higher risk for severe inflammation and atrophy.	24965801
Inflammation, Intracranial Aneurysm	Altered Intercellular Communication	As there is increasing evidence that inflammation is contributing significantly to the pathogenesis of intracranial aneurysms, melanocyte-like cells may be relevant in preventing age-related impairment of vessels.	24967348
Inflammation, No metabolic abnormalities, Hepatocarcinogenesis	Altered Intercellular Communication	Obesity-related metabolic abnormalities, including adipokine imbalance and chronic inflammation, are involved in liver carcinogenesis.	24968270
Inflammation	Altered Intercellular Communication	Chemerin, a novel adipokine, plays a critical role in adipogenesis, energy metabolism, and inflammation.	24968270
Inflammation, Atherosclerosis	Altered Intercellular Communication	DPP4 activity is an important predictor of the onset of inflammation and atherosclerosis in apparently healthy Chinese.	24968315
Inflammation, B-Cell Lymphomas	Altered Intercellular Communication	Serum lactate dehydrogenase with a systemic inflammation score is useful for predicting response and survival in patients with newly diagnosed diffuse large B-cell lymphoma.	24969101
HD Term Type, Inflammation	Altered Intercellular Communication	Also, inflammation is a common feature in HD patients.	24969183
Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	Therefore, a low level of fetuin-A seems to be associated with atherosclerosis, inflammation and malnutrition.	24969186
Crohn Disease, Intestinal Microbiome, Gastrointestinal inflammation	Altered Intercellular Communication	Recent studies indicate that persistent intestinal inflammation in patients with Crohn's disease (CD) might be caused by abnormal intestinal microbiota.	24969283
Inflammation, Perforation (observation)	Altered Intercellular Communication	The question of feasibility also arises in cases of advanced inflammation with perforation.	24969344
Inflammation, Neuroendocrine Tumors	Altered Intercellular Communication	Furthermore, there were two findings without inflammation, namely one neurogenic appendicopathy and one neuroendocrine tumor.	24969344
Narcolepsy, Sleep Disorders	Altered Intercellular Communication	These sleep problems partly resemble the core symptoms of narcolepsy, a sleep disorder caused by a general loss of the neurotransmitter hypocretin.	24969517
Inflammation, Depression, CTCAE, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus	Altered Intercellular Communication	Because of the absence of data on the direct association between inflammation and depression in patients with diabetes, we examined the association between hs-CRP levels and the high prevalence of depression in adult patients with type 2 diabetes.	24969579
Inflammation	Altered Intercellular Communication	Plasma neutrophil gelatinase-associated lipocalinin in the general population: association with inflammation and prognosis.	24969771
Data types - Address	Altered Intercellular Communication	The results suggest an early functional impairment of cholinergic neurotransmission in AD, which is associated to early changes in the excitability of the motor system.	24969819
Inflammation	Altered Intercellular Communication	IRIS consists in a sudden change in the dominant T-helper responses to inflammation, which is not balanced by anti-inflammatory response, playing a critical role in microbial pathogenesis.	24970001
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Inflammatory disorder, Cardiovascular Diseases	Altered Intercellular Communication	The risk of cardiovascular diseases and type 2 diabetes mellitus is increased across a range of organ-specific and multisystem chronic inflammatory disorders with evidence that risk is associated with severity of inflammation.	24970784
Refractory anemias	Altered Intercellular Communication	Recently, A20 was identified as a key negative regulator for T cell activation and inflammatory signaling and may be involved in RA pathogenesis.	24971370
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Sixteen polymorphisms in 13 genes involved in regulation of inflammation were associated with risk of CD and/or UC (p <= 0.05).	24971461
Inflammation, GRN wt Allele	Altered Intercellular Communication	Collectively, our findings suggest that circulating PGRN is significantly associated with systemic insulin sensitivity and autophagic activity in adipose tissue and support the notion that PGRN functions as a potential link between chronic inflammation and insulin resistance.	24971611
Ischemia, Inflammation, Neurotoxicity Syndromes	Altered Intercellular Communication	Plant hydroethanolic extracts were prepared and tested in a panel of phenotypic screening assays that reflect multiple neurotoxicity pathways relevant to AD-oxytosis in hippocampal nerve cells, in vitro ischemia, intracellular amyloid toxicity, inhibition of microglial inflammation and nerve cell differentiation.	24971794
Inflammation, Visceral Pain	Altered Intercellular Communication	Visceral pain is strongly associated with inflammation and distension of the gut.	24972070
Inflammation, Aortic Aneurysm, Abdominal, atherosclerotic	Altered Intercellular Communication	Atherosclerotic risk factors and atherosclerotic postoperative events are associated with low inflammation in abdominal aortic aneurysms.	24972144
Inflammation, Glucocorticoid deficiency with achalasia, atherosclerotic, Atherosclerotic lesion	Altered Intercellular Communication	Low amount of inflammation in AAAs is associated with more atherosclerotic risk factors, more advanced local atherosclerotic lesions and more postoperative atherosclerotic adverse events.	24972144
Peripheral Vascular Diseases	Altered Intercellular Communication	Autologous bone marrow mononuclear cell therapy improves symptoms in patients with end-stage peripheral arterial disease and reduces inflammation-associated parameters.	24972744
Inflammation	Altered Intercellular Communication	Autologous BM-MNC therapy in patients with end-stage PAD improves tissue perfusion indices and decreases markers of inflammation.	24972744
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Proteinase-activated receptor-1 (PAR-1) plays a key role in mediating the interplay between coagulation and inflammation in response to injury.	24973402
Inflammation	Altered Intercellular Communication	Laboratory data: elevated transaminases, markers of inflammation negative, all bacterial cultures negative.	24974673
Inflammation, Respiratory Failure, Thrombocytopenia	Altered Intercellular Communication	Subsequently, the inflammation, respiratory failure, and thrombopenia rapidly improved, and the patient was extubated on day 12.	24974932
Inflammation, Primary malignant neoplasm, Neoplasms, Muscle (organ)	Altered Intercellular Communication	There is limited information on the impact of age, sex, tumor type, and inflammation on muscle loss in the end of life of cancer patients.	24975045
Inflammation, Primary malignant neoplasm, Neoplasms, Muscle (organ)	Altered Intercellular Communication	Muscle loss in advanced cancer is related to age, sex, tumor type, and inflammation.	24975045
Inflammation, Fatigue	Altered Intercellular Communication	Among various psychological stress response variables, general fatigue may be a key determinant of low-grade inflammation as represented by increases of WBC and neutrophil counts.	24975105
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation was the most frequent histological finding (56%).	24975504
Inflammation, Obesity	Altered Intercellular Communication	High-oleic peanuts: new perspective to attenuate glucose homeostasis disruption and inflammation related obesity.	24975522
Inflammation, Deep thrombophlebitis	Altered Intercellular Communication	We found no evidence of systemic inflammation in patients with PTS at 63months since the last DVT.	24975586
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	Inflammation perpetuates individual tumor progression resulting in decreased survival in cancer patients.	24975677
Inflammation, Inflammatory disorder, Pyeloureteritis cystica	Altered Intercellular Communication	Pyeloureteritis cystica is described as a benign inflammatory disease of the urinary tract, resulting from chronic inflammation of the urothelium.	24975787
ARCN1 gene, Inflammation, alpha 1-Antitrypsin Deficiency	Altered Intercellular Communication	These data show that AATD COPD patients do not experience the same chronic systemic inflammation and exhibit reduced inflammation compared to non-AATD COPD patients.	24975928
Inflammation, Disease	Altered Intercellular Communication	Therefore, alterations in innate immunity could explain the inflammation and T-cell autoreactivity leading to the development of LP disease.	24976336
ARCN1 gene, Inflammation	Altered Intercellular Communication	Long-term home noninvasive mechanical ventilation (NIV) is beneficial in COPD but its impact on inflammation is unknown.	24976687
Pneumonitis	Altered Intercellular Communication	These findings challenge prior paradigms based on the assumption that pulmonary inflammation is per se detrimental.	24976687
Autoimmune Diseases, Arthralgia, Chemosis of conjunctiva, Xerostomia, Orbital Pseudotumor, Inflammatory disorder	Altered Intercellular Communication	Female gender, family history of autoimmune disease, self-reported joint pain or dry mouth, external signs of orbital inflammation, and conjunctival chemosis were more common in patients with inflammatory systemic disease as compared with that in patients with no identifiable condition (P < 0.05 for all).	24977987
Scleritis, Secondary glaucoma	Altered Intercellular Communication	Scleritis with secondary glaucoma, although usually associated with inflammatory conditions, can rarely be a manifestation of adult T-PLL.	24977988
Sialadenitis, Inflammation, Fibrosis Assessment, Atrophic	Altered Intercellular Communication	Subsequent biopsy of the left lacrimal gland revealed chronic inflammation with lymphoid aggregate formation, atrophy, and fibrosis consistent with chronic sialadenitis, and an incisional biopsy of the cervical lymph node showed salivary gland tissue with inflammation as well.	24978334
Cherubism, Inflammation, Osteopenia	Altered Intercellular Communication	Etanercept administration to neonatal SH3BP2 knock-in cherubism mice prevents TNF-a-induced inflammation and bone loss.	24978678
Cherubism, Inflammation, destruction joint, Erosion of bone	Altered Intercellular Communication	In a knock-in mouse model for cherubism, we previously demonstrated that homozygous mutant mice develop T/B cell-independent systemic macrophage inflammation leading to bone erosion and joint destruction.	24978678
Cherubism, Tumor necrosis, bone destruction, Inflammation	Altered Intercellular Communication	We identified a critical role of tumor necrosis factor a (TNF-a) in the development of autoinflammation by creating homozygous TNF-a-deficient cherubism mutants, in which systemic inflammation and bone destruction were rescued.	24978678
Inflammation, Osteopenia	Altered Intercellular Communication	However, inflammation and bone loss, which were successfully treated by etanercept administration, recurred after etanercept discontinuation.	24978678
Cherubism, Inflammation, Pneumonitis, Osteopenia	Altered Intercellular Communication	In contrast, when 10-week-old cherubism mice with fully active inflammation were treated with etanercept for 7 weeks, even the high-dose administration did not decrease bone loss or lung or liver inflammation.	24978678
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The relation of hepcidin to iron disorders, inflammation and hemoglobin in chronic kidney disease.	24978810
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We investigated its relation to iron disorders, inflammation and hemoglobin (Hb) level in 199 non-dialyzed, non-transplanted patients with CKD stages 1-5.	24978810
Sepsis, Inflammation	Altered Intercellular Communication	Age-related differences in biomarkers of acute inflammation during hospitalization for sepsis.	24978893
Sepsis	Altered Intercellular Communication	Adjustment or stratification by sepsis severity did not change the age-inflammation associations.	24978893
Sepsis, Inflammation, Septic Shock	Altered Intercellular Communication	Although older adults had higher levels of inflammation at presentation and an increased incidence of severe sepsis and septic shock, these age-related differences in inflammation largely resolved during the first 72 h of hospitalization.	24978893
Inflammation, selenium, Chaos	Altered Intercellular Communication	Our results suggest that SES moderates the detrimental effect of family chaos on systemic inflammation and interleukin-6 (B = -0.010, standard error [SE] = 0.004, p = .026), but not C-reactive protein (B = 0.009, SE = 0.006, p = .11), and on stimulated proinflammatory cytokine production (B = -0.098, SE = 0.044, p = .026) in adolescents, such that a chaotic family environment is positively associated with greater systemic inflammation and greater stimulated proinflammatory cytokine production in adolescents as family SES declines.	24979577
Inflammatory disorder	Altered Intercellular Communication	These findings indicate that living in chaotic family environments places youth who may be vulnerable based on socioeconomic factors at a potentially higher risk for inflammation-related diseases.	24979577
Inflammatory abnormality of the eye, Sensorineural Hearing Loss (disorder), Autoimmune vasculitis, Oculovestibuloauditory syndrome	Altered Intercellular Communication	Cogan's syndrome (CS) is a rare autoimmune vasculitis characterized by ocular inflammation and sensorineural hearing loss.	24979832
Autoimmune Diseases, Sensorineural Hearing Loss (disorder), Inflammatory abnormality of the eye	Altered Intercellular Communication	"Atypical" CS is conceivably a sort of "melting pot" of different forms of autoimmune diseases still characterized by ocular inflammation and sensorineural hearing loss but whose antigenic characteristics need to be further defined.	24979832
Inflammation	Altered Intercellular Communication	Dynamics of inflammation resolution and symptom recovery during AECOPD treatment.	24980048
Airway structure, ARCN1 gene	Altered Intercellular Communication	The association between increases in both systemic and airway inflammation and acute exacerbation of COPD (AECOPD) has been reported by many studies.	24980048
Dyspnea, Upper Respiratory Infections	Altered Intercellular Communication	Notably, lung function and dyspnea improved to the baseline level by day 4 as well, consistent with the resolution of respiratory inflammation.	24980048
Airway structure	Altered Intercellular Communication	In summary, we observed a time lag between the resolution of systemic and airway inflammation, which were correlated with the improvements of different clinical indices.	24980048
Inflammation, Impaired cognition	Altered Intercellular Communication	Disability was associated with the DC (crude odds ratio, OR: 2.1; 95% confidence interval, CI: 1.4-3.4), CCI (crude OR: 1.8; 95% CI: 1.2-2.7) and CIRS (crude OR: 4.0; 95% CI: 2.5-6.5); only the association with CIRS was independent of age, sex, chronic inflammation, impaired cognition and frailty (adjusted OR: 3.2; 95% CI: 1.7-5.8).	24980394
Inflammation, Impaired cognition, Frailty	Altered Intercellular Communication	Frailty was associated with CCI (crude OR: 2.4; 95% CI: 1.2-4.6) and CIRS (crude OR: 2.6; 95% CI: 1.3-5.3); adjusted for age, sex, chronic inflammation, impaired cognition and disability.	24980394
Migraine Disorders, Inflammation	Altered Intercellular Communication	We propose that in our patient the occipital neurocysticercosis lesions cause migraine without aura-like attacks via inflammation in the surrounding brain parenchyma leading to sensitization of the trigemino-vascular system.	24980846
Diverticulitis, Inflammatory disease of mucous membrane, Diverticular Diseases	Altered Intercellular Communication	Diverticular colitis is a newly established disorder of chronic segmental mucosal inflammation affected by diverticular disease.	24980998
Inflammation, Coronary Artery Disease, Diabetes Mellitus	Altered Intercellular Communication	Insights from a thermography-based method suggesting higher carotid inflammation in patients with diabetes mellitus and coronary artery disease.	24981292
Inflammation	Altered Intercellular Communication	Alterations in the pouch and the proximal SB were comparable, suggesting that inflammation may not be limited to the pouch, but that it extends to the proximal SB.	24982202
Inflammation, Rheumatoid Factor	Altered Intercellular Communication	Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation.	24982240
Refractory anemias, Inflammation	Altered Intercellular Communication	Additionally, MMP-9 stimulates RA synovial fibroblast-mediated inflammation and degradation of cartilage, whereas MMP-2 inhibits these parameters.	24982240
Malignant Biliary Obstruction	Altered Intercellular Communication	Inflammation-based prognostic score predicts biliary stent patency in patients with unresectable malignant biliary obstruction.	24982377
Primary malignant neoplasm	Altered Intercellular Communication	An inflammation-based prognostic score, the modified Glasgow prognostic score (mGPS), has been reported to be useful for predicting postoperative survival in patients with various types of cancer.	24982377
Inflammation, Malnutrition	Altered Intercellular Communication	Prealbumin and albumin may be sensitive indicators of disturbances in protein metabolism, and reflect inflammation activity and malnutrition.	24982401
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The neutrophil:lymphocyte ratio (NLR) has been reported to reflect systemic inflammation and to have independent prognostic value for patients with various cancers.	24982408
Inflammation	Altered Intercellular Communication	Noninfectious inflammation after intravitreal injection of aflibercept: clinical characteristics and visual outcomes.	24983791
Inflammation	Altered Intercellular Communication	To report the presenting features and clinical outcomes of a series of patients with noninfectious inflammation after intravitreal aflibercept injection.	24983791
Inflammation	Altered Intercellular Communication	Medical records of patients who presented with noninfectious inflammation after intravitreal aflibercept injection between November 18, 2011 and June 30, 2013 were retrospectively reviewed.	24983791
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Role of HMGB1 as a suitable biomarker of subclinical intestinal inflammation and mucosal healing in patients with inflammatory bowel disease.	24983978
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Noninvasive biomarkers of high- and low-grade intestinal inflammation and of mucosal healing (MH) in patients with inflammatory bowel disease are currently lacking.	24983978
Inflammation	Altered Intercellular Communication	We have recently shown that fecal high mobility group box 1 (HMGB1) protein is a novel biomarker of gut inflammation.	24983978
Inflammation	Altered Intercellular Communication	We aimed at investigating in a mouse model if HMGB1 was able to foresee both a clinically evident and a subclinical gut inflammation and if its normalization indicated MH.	24983978
Inflammation	Altered Intercellular Communication	Fecal HMGB1 increased by 5-, 11-, 18-, and 24-folds with dextran sodium sulphate doses of 0.25%, 0.50%, 1%, and 4%, respectively, showing that the protein detected a high-grade and a subclinical inflammation.	24983978
Inflammation	Altered Intercellular Communication	Fecal HMGB1 is a robust noninvasive biomarker of clinically overt and subclinical gut inflammation; it can also be a surrogate marker of MH.	24983978
Arterial Stiffness, Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Secondary endpoints included characteristics of the MetS, namely endothelial function, arterial stiffness and inflammation.	24984823
Inflammation, Obstructive sialadenitis, Rectal Obstruction, CTCAE	Altered Intercellular Communication	Obstructive sialadenitis of a transplanted submandibular gland: chronic inflammation secondary to ductal obstruction.	24985728
Inflammation, Obstructive sialadenitis, Rectal Obstruction, CTCAE	Altered Intercellular Communication	Obstructive sialadenitis of transplanted SMGs is a chronic inflammation secondary to ductal obstruction, which leads to insufficient ocular lubrication and potential treatment failure.	24985728
Communicable Diseases, Idiopathic bronchiectasis, Inflammation, Damage	Altered Intercellular Communication	Idiopathic bronchiectasis is a poorly defined disease characterised by persistent inflammation, infection and progressive lung damage.	24986480
Inflammation, Breast Carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Chronic inflammation is associated with increased risk of multiple cancers, including breast cancer.	24986698
Airway structure, Asthma, Respiratory Tract Infections	Altered Intercellular Communication	Vitamin D modifies airway inflammation and appears to be important in building immunity against respiratory infections, and so is potentially beneficial in asthma.	24986817
Refractory anemias, Inflammation, Tumor necrosis	Altered Intercellular Communication	Despite elevated systemic inflammation [interleukin (IL)-6, IL-18, tumor necrosis factor-a; p < 0.05 for all], persons with RA were not less insulin sensitive [SI geometric mean (SD): RA 4.0 (2.4) vs control 4.9 (2.1)*10(-5) min(-1)/(pmol/l); p = 0.39].	24986846
Refractory anemias, Inflammation	Altered Intercellular Communication	In established and treated RA, traditional risk factors, specifically excess adiposity, play more of a role in predicting skeletal muscle insulin sensitivity than do systemic inflammation or other disease-related factors.	24986846
Inflammation	Altered Intercellular Communication	There was a good correlation between CCE and colonoscopy in disease severity (k=0.79; 95% confidence interval: 0.62-0.96) and extent of inflammation (k=0.71; 95% confidence interval: 0.52-0.90) observed.	24987825
Inflammation, Refractory anemias, Rheumatoid Arthritis, Inflammatory disorder, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Type 2 diabetes is associated with chronic, low-grade inflammation and could potentially trigger the progression of other, more prominent inflammatory diseases such as rheumatoid arthritis (RA).	24988532
Refractory anemias, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Our findings were consistent with the hypothesis that chronic low-grade inflammation in type 2 diabetes may elicit the development of RA in genetically susceptible individuals.	24988532
Inflammation, Cachexia, Malignant Head and Neck Neoplasm	Altered Intercellular Communication	The purpose of this study was to evaluate the prognostic potential of the modified Glasgow prognostic score (mGPS), known to reflect the degree of tumor-associated inflammation and cancer cachexia, in patients with advanced head and neck cancer.	24989115
Inflammation, Chronic granulomatous disease	Altered Intercellular Communication	Clinically, dysregulated inflammation by excessive cytokine production due to loss of reactive oxygen species production is suggested as a cause of noninfectious inflammatory problems such as chronic granulomatous disease colitis.	24989247
Inflammation, Fibrosis Assessment, Insemination, Artificial, Homologous	Altered Intercellular Communication	Five remarkable points should be emphasized: (i) a long latency interval, despite the acute presentation; (ii) exacerbation of liver biochemical parameters, even after drug cessation; (iii) the paired liver biopsies indicating continuing inflammation and disappearance of toxic features; (iv) a positive DLST and the absence of fibrosis consistent with DIAIH and not AIH; and (v) a rare histological feature of MS. Intense immunoallergic reactions were likely triggers of MS in the current case.	24989642
Icterus, Inflammation	Altered Intercellular Communication	A possibility of DIAIH should be considered in cases of DILI which exhibit overt jaundice, autoantibodies, intense histological inflammation and a long latency period.	24989642
Eosinophilic inflammation	Altered Intercellular Communication	Nasal fluid release of eotaxin-3 and eotaxin-2 in persistent sinonasal eosinophilic inflammation.	24989688
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Despite enrichment of Treg cells in joints of rheumatoid arthritis (RA) patients, local inflammation persists.	24990235
Inflammation, Liver Cirrhosis, FAM126A gene	Altered Intercellular Communication	HCC predominantly develops in the condition of chronic inflammation that has led to liver cirrhosis.	24990270
Inflammation, Ischemic stroke	Altered Intercellular Communication	Immune responses and inflammation are key elements in the pathogenesis of ischemic stroke (IS).	24991091
Inflammation, HIV Infections	Altered Intercellular Communication	Chronic inflammation is a hallmark of HIV infection.	24991090
Pancreatitis	Altered Intercellular Communication	Our study demonstrated that cryptogenic pancreatic inflammation with fatty changes represents an important predisposing factor for PDAC.	24991971
Waldenstrom Macroglobulinemia, Fibrosis Assessment	Altered Intercellular Communication	Biopsy specimens taken from the parietal pleura revealed lymphoplasmacytic inflammation with fibrosis.	24992134
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Critical role of RIG-I-like receptors in inflammation in chronic obstructive pulmonary disease.	24992168
Airway structure, ARCN1 gene	Altered Intercellular Communication	Our results suggested that MDA-5, but not RIG-I, may play a critical role in airway inflammation in COPD.	24992168
Communicable Diseases, Postoperative Complications, Inflammation	Altered Intercellular Communication	A high preoperative CRP level predicts an increased rate of postoperative complication due to established inflammation and/or infection.	24992421
Histiocytosis, Langerhans-Cell, Inflammation	Altered Intercellular Communication	Oral manifestion of Langerhans cell histiocytosis mimicking inflammation.	24992857
Histiocytosis, Langerhans-Cell, Inflammation	Altered Intercellular Communication	A case of LCH in a 6-year-old girl involving the mid root level of developing first permanent molar with a floating developing tooth bud of permanent second molar mimicking an inflammation is reported.	24992857
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Fecal level of calprotectin identifies histologic inflammation in patients with ulcerative colitis in clinical and endoscopic remission.	24993368
Inflammation, Colorectal Neoplasms	Altered Intercellular Communication	Persistent active microscopic inflammation is associated with an increased risk of relapse and colorectal neoplasia.	24993368
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Histologic inflammation is common among patients with UC in clinical and endoscopic remission.	24993368
Inflammation, Eosinophilic esophagitis, Esophagitis	Altered Intercellular Communication	Markers of eosinophilic inflammation for diagnosis of eosinophilic esophagitis and proton pump inhibitor-responsive esophageal eosinophilia: a prospective study.	24993367
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Chronic Kidney Diseases	Altered Intercellular Communication	Long-term effects of moderate protein diet on renal function and low-grade inflammation in older adults with type 2 diabetes and chronic kidney disease.	24993749
Communicable Diseases, Inflammation	Altered Intercellular Communication	Osteopontin (OPN) and soluble urokinase plasminogen activator receptor (suPAR) have been proposed as markers of disease severity and risk-stratification in infection and inflammation.	24994498
Inflammation	Altered Intercellular Communication	Because of the acute onset and signs of acute inflammation, an X-ray was arranged.	24995443
Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation, oxidative stress, and diabetes are common in patients with chronic kidney disease (CKD), particularly in those with cardiovascular disease (CVD).	24995525
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	The coexistence of diabetes and oxidative stress independently affected CCL23 levels, while the presence of CVD and inflammation had no impact on its concentrations.	24995525
Inflammation, Prostate carcinoma	Altered Intercellular Communication	The neutrophil-to-lymphocyte ratio (NLR), a marker of inflammation, has been reported to be a poor prognostic indicator in prostate cancer.	24995769
Inflammation, Asteroids	Altered Intercellular Communication	A fine-needle cytology of the axillary lymph node showed extensive granulomatous inflammation, numerous histiocytes, and multinucleated giant cells containing star-shaped structures known as "asteroid bodies."	24995825
Carcinogenesis, Malignant Neoplasms, Pancreatitis	Altered Intercellular Communication	Regenerating islet-derived protein 3-alpha (Reg3A) has been reported overexpressed in pancreatic inflammation and associated with PaC malignancies, thus believed as a potential target in inflammation-linked pancreatic carcinogenesis.	24996521
Inflammation, Cyst	Altered Intercellular Communication	We drained the cyst using transesophageal endoscopic ultrasonography to control the inflammation and decrease the size of the cyst; we subsequently resected the cyst.	24996718
prostatitis, Erectile dysfunction	Altered Intercellular Communication	Asymptomatic prostatic inflammation in men with clinical BPH and erectile dysfunction affects the positive predictive value of prostate-specific antigen.	24996777
Sexual Dysfunction, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	To test the hypothesis that sexual dysfunction in elderly men with benign prostatic hyperplasia leads to prostatic inflammation, diagnosed by prostatic fluid interleukin-8 (IL-8), which lowers the positive predictive value of prostate-specific antigen (PSA).	24996777
Inflammation, Benign prostatic hypertrophy, Erectile dysfunction	Altered Intercellular Communication	Men with symptomatic benign prostatic hyperplasia and erectile dysfunction had significant inflammation of the prostate to cause spurious rise in PSA level resulting in an unnecessary biopsy.	24996777
Drug-induced, Psychogenic	Altered Intercellular Communication	The causes of ED was classified as psychogenic (59.2%), vasoculogenic (21.3%), neurogenic (4.1%), anatomical/structural (2.8%), hormonal (7.1%) or drug-induced (5.5%).	24996819
Inflammation	Altered Intercellular Communication	Aging is commonly accompanied by increased arterial and ventricular stiffness (determined by arterial elastance (Ea) and ventricular elastance (Elv)), augmented ventricular-vascular coupling ratios (Ea/Elv) and systemic inflammation.	24996847
Inflammation	Altered Intercellular Communication	Acute inflammation may impact ventricular-vascular coupling and predispose older adults to cardiovascular events.	24996847
Each (qualifier value)	Altered Intercellular Communication	Ea and Ea/Elv were maintained (p > 0.05), but Elv was reduced (p < 0.05) 24 h post-inflammation.	24996847
Inflammation	Altered Intercellular Communication	Older, but not younger, adults decreased central pressure during inflammation (p < 0.05).	24996847
Inflammation	Altered Intercellular Communication	Aging, not physical activity, appears to modulate cardiovascular responses to acute inflammation, except in the most active older adults.	24996847
Aggressive course, "Alzheimers Disease", Depressed mood	Altered Intercellular Communication	Monoaminergic neurotransmitter alterations in postmortem brain regions of depressed and aggressive patients with Alzheimer's disease.	24997673
APP gene, Inflammation, vascular associated smooth muscle cell apoptotic process, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	The pathogenesis of abdominal aortic aneurysm (AAA) formation includes inflammation, vascular smooth muscle cell apoptosis, extracellular matrix degradation, and oxidative stress.	24997808
Inflammation, Metabolic Syndrome X, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP) is a marker of inflammation which has been shown in multiple prospective epidemiological studies to predict the risk of cardiovascular disease and metabolic syndrome.	24998076
Inflammation, Disease, Obesity	Altered Intercellular Communication	Inflammation may accompany obesity and a variety of diseases, or result from excessive exercise.	24998353
Interstitial inflammation, Cyst, Pleurisy, Bronchiolitis, muscle hyperplasia, Infiltration	Altered Intercellular Communication	Pathologically, in the UIP/pSS group, interstitial inflammation, plasma cell infiltration, lymphoid follicles with germinal centers, cysts, bronchiolitis, and pleuritis were significantly more prominent, whereas smooth muscle hyperplasia and fibroblastic foci were milder (all P<0.05).	24998369
Airway structure, Residual volume	Altered Intercellular Communication	Formoterol and budesonide may inhibit RV infection by reducing the ICAM-1 levels and/or acidic endosomes and modulate airway inflammation associated with RV infections.	24998372
Inflammation	Altered Intercellular Communication	Elderly individuals usually present chronic low level inflammation, likely as the consequence of continued exposure to antigens combined with poor immune function, increases in production of pro-inflammatory cytokines by effector memory and senescent T cells and macrophages.	24998470
Inflammation	Altered Intercellular Communication	In this work we analyse NK cell subsets in the elderly in relation with markers of inflammation and health status.	24998470
Inflammation, Skin Basal Cell Carcinoma	Altered Intercellular Communication	We conclude that NLR, a basal cancer related inflammation marker, is associated with the resistance to bevacizumab- based treatments in mCRC patients.	24998541
Inflammation, Crohn Disease	Altered Intercellular Communication	To define the best independent predictors for active inflammation in patients with Crohn disease (CD) examined by contrast-enhanced magnetic resonance (MR) enterography.	24998692
Inflammation, With intensity	Altered Intercellular Communication	The bowel wall T2 hyperintensity and the length of the involved bowel tract were predictors of active inflammation in patients with CD examined by contrast-enhanced MR enterography.	24998692
Inflammation, Abnormal degeneration	Altered Intercellular Communication	Muscle biopsy typically reveals endomysial inflammation, invasion of mononuclear cells into non-necrotic fibers and rimmed vacuoles, suggesting inflammation and degeneration co-exist as part of the pathomechanism.	24998819
Inflammation, TP53 gene, Neoplasms	Altered Intercellular Communication	Loss of Cdh1 and Trp53 in the uterus induces chronic inflammation with modification of tumor microenvironment.	24998851
Inflammation, Neoplasms	Altered Intercellular Communication	These results indicate that absence of CDH1 and TP53 in endometrial cells initiates chronic inflammation, promotes tumor microenvironment development following the recruitment of macrophages and promotes aggressive ECs.	24998851
Inflammation, Hyperkeratosis, Koilocytotic atypia, Hypergranulosis, Acanthosis, Hyperplasia	Altered Intercellular Communication	Punch biopsy of the hallux nail bed revealed epidermal hyperplasia, acanthosis, hypergranulosis, hyperkeratosis, and regions of koilocytosis without significant inflammation.	24999548
Retinal Vasculitis, Inflammatory abnormality of the eye	Altered Intercellular Communication	Disease activity markers, including signs of ocular inflammation, evidence of retinal vasculitis, Swedish interactive threshold algorithm-short wavelength automated perimetry Humphrey visual field analysis, electroretinographic parameters, and optical coherence tomography were recorded.	24999722
Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation was present in 54.5, 9.9, 11.1, and 0% of patients at baseline, 6 months, 1 year, 2 years, 3 years, and beyond 3 years after receiving the implant, respectively.	24999722
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	The degree of inflammation within the atherosclerotic plaque can be detected non-invasively by positron emission tomography (PET) with 18F-fluorodeoxyglucose (18F-FDG).	25000124
Dermatitis, Eczema	Altered Intercellular Communication	Chronic hand eczema is defined as a persistent (>6 months' duration) noninfectious skin inflammation of the hands.	25000239
Inflammation	Altered Intercellular Communication	Russell body esophago-gastro-duodenitis is an unusual form of chronic inflammation, with only 22 cases being reported in PubMed.	25001185
Inflammation, Tooth structure, Tooth Loss, Osteopenia	Altered Intercellular Communication	Characteristics of AP are gingival inflammation, deep periodontal pockets, bone loss, tooth mobility and even tooth loss.	25001360
Gingivitis	Altered Intercellular Communication	A 4-year-old girl presented with signs of severe gingival inflammation.	25001360
Parotitis, Juvenile rheumatoid arthritis	Altered Intercellular Communication	Juvenile recurrent parotitis (JRP) is a nonobstructive, nonsuppurative parotid inflammation in young children.	25001449
Inflammation, Hemorrhage, Communicable Diseases, Cartilaginous exostosis, Irritation	Altered Intercellular Communication	It is well established that irregular bursae can form adjacent to an osteochondroma (bursa exostotica) as a result of mechanical irritation and that these bursae can be complicated by inflammation, hemorrhage, or infection.	25001874
Alzheimers Disease", Inflammation	Altered Intercellular Communication	Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction.	25002035
Impaired cognition, Data types - Address, physiopathological	Altered Intercellular Communication	Based on these findings we argue that chronically proinflammatory astrocyte and microglia phenotypes, showing a reduction of genes involved in neuronal support and neuronal signaling, are likely to contribute to the neuronal dysfunction and cognitive decline in AD.	25002035
Inflammation, COL4A2 wt Allele, Edema	Altered Intercellular Communication	We hypothesized that modulation of brain inflammation reduces edema, thus improving clinical outcomes in patients with ICH.	25003359
Inflammation, Acanthosis, Fibrosis Assessment	Altered Intercellular Communication	Pathology specimens from skin flaps showed extensive acute and chronic inflammation, microabscesses, fibrosis, and acanthosis, with depletion and degeneration of the pilosebaceous units.	25003411
Inflammation, Tumor necrosis, Pain Distress Question, MMP8 wt Allele	Altered Intercellular Communication	While studies suggest an association between chronic inflammation and pain, levels of inflammatory cytokines, such as C-reactive protein (CRP) and tumor necrosis factor-alpha (TNF-a), have not been correlated with pain in HNC patients who are not currently undergoing anticancer treatment.	25003634
Inflammation, Anemia, HIV Infections	Altered Intercellular Communication	Markers of inflammation and activation of coagulation are associated with anaemia in antiretroviral-treated HIV disease.	25003720
Inflammation, Anemia, Thrombophilia	Altered Intercellular Communication	Persistent inflammation and hypercoagulation appear to be associated with anaemia.	25003720
Left Ventricular Hypertrophy, Inflammation, Cardiomyopathies, Myocardial dysfunction, Atherosclerosis	Altered Intercellular Communication	Epicardial adipose tissue is related to coronary atherosclerosis, left ventricle hypertrophy, myocardial dysfunction, cardiomyopathy, and inflammation, which produces a variety of cytokines that influence key pathogenic mechanisms of atherogenesis.	25004239
Carcinomatosis, Inflammation	Altered Intercellular Communication	Inflammation plays a central role in peritoneal carcinomatosis (PC) etiology and progression, and circulating levels of inflammatory biomarkers prior to surgery predict progression-free and overall survival in PC patients.	25004281
Pain Distress Question, Inflammation	Altered Intercellular Communication	Her shoulder pain worsened, and examination demonstrated inflammation over the sternoclavicular joint.	25004310
Arthritis	Altered Intercellular Communication	Thus, anti-CII antibodies may both contribute to, as well as be the consequence of, local joint inflammation.	25005029
Inflammation	Altered Intercellular Communication	The present case reinforces the notion that Modic type I change corresponds to reversible local inflammation.	25005163
Communicable Diseases, Uveitis	Altered Intercellular Communication	We describe a rare case of extraocular inflammation secondary to scleral buckle infection with Alcaligenes xylosoxidans.	25005211
Celiac Disease, Inflammation, Crypt hyperplasia, Villous atrophy	Altered Intercellular Communication	The small-bowel mucosal damage characteristic of celiac disease (CD) develops from normal villus morphology to inflammation and finally to villus atrophy with crypt hyperplasia.	25005738
Ulcer, Inflammation, Crohn Disease	Altered Intercellular Communication	The VCE in May 2007 found patchy inflammation and superficial ulcers in the terminal ileum consistent with Crohn's disease.	25006053
Inflammation, Intraepithelial Lymphocytosis, Colitis	Altered Intercellular Communication	Nine years later, a colectomy revealed a form of microscopic colitis in which significant intraepithelial lymphocytosis and collagen plate thickening have disappeared while GCs persisted with diffuse mononuclear cells inflammation of the lamina propria.	25006169
Inflammation	Altered Intercellular Communication	Esophagogastric fistula is a rare complication related to severe inflammation at the gastroesophageal junction.	25007128
Inflammation	Altered Intercellular Communication	Macrophages are important components of the tumor-associated infiltrate and are qualified as one of the major players of the cancer-related inflammation.	25007179
Airway structure, ARCN1 gene	Altered Intercellular Communication	Eosinophilic airway inflammation is observed in 10-30% of COPD subjects.	25007795
Acute Coronary Syndrome	Altered Intercellular Communication	They represent an important mode of intercellular communication, and their number is increased in patients with acute coronary syndromes.	25007837
Inflammatory abnormality of the eye	Altered Intercellular Communication	Control of ocular inflammation was achieved in 38 of 40 (95%).	25007956
Traumatic, Thyrotoxicosis, Thyroiditis	Altered Intercellular Communication	Thyroid function tests confirmed the clinical suspicion of progressive thyrotoxicosis, with associated imaging consistent with thyroid inflammation secondary to band-like traumatic pressure to the lower half of the thyroid gland.	25008337
Inflammation, Contrast - Induced Nephropathy	Altered Intercellular Communication	The role of inflammation in contrast-induced nephropathy.	25009948
Inflammation, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	Ongoing inflammation doubles the likelihood of development of CIN.	25009948
Inflammation, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	This study highlights the importance of inflammation as a risk factor in the development of CIN.	25009948
Lower Urinary Tract Symptoms, prostatitis	Altered Intercellular Communication	Effects of prostatic inflammation on LUTS and alpha blocker treatment outcomes.	25010301
prostatitis	Altered Intercellular Communication	Prostatic inflammation was scored as none (0), mild (I), moderate (II), or marked (III).	25010301
Inflammation	Altered Intercellular Communication	Lower grade inflammation was related to higher urine flow rate at baseline.	25010301
Inflammation	Altered Intercellular Communication	Patients with higher inflammation grades had larger prostate volumes, larger total and transitional zone volumes, and higher PSA levels.	25010301
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	Eighty percent of patients with grade 0 inflammation, 73% of patients with grade I inflammation, and 92.3% of patients with grade II inflammation showed improvement of LUTS after treatment.	25010301
Inflammation, Prostate	Altered Intercellular Communication	Patients with high grade inflammation had lower flow rates and higher prostatic volumes than patients with low grade inflammation.	25010301
Acute inflammation, cell wall thickening	Altered Intercellular Communication	Of these 65 patients, 61 underwent scrotoscopy and minimal hydrocelectomy, two patients underwent open hydrocelectomy because thickening of hydrocele wall was identified; two patients with acute inflammation only underwent scrotoscopy.	25010305
Inflammation	Altered Intercellular Communication	There was a significant reduction in the area and severity of the palatal inflammation (P < .0001).	25010873
Inflammation, Chronic disease	Altered Intercellular Communication	Many biodemographic studies use biomarkers of inflammation to understand or predict chronic disease and aging.	25011077
Inflammation	Altered Intercellular Communication	chronic low-grade inflammation during aging, is commonly characterized by pro-inflammatory biomarkers.	25011077
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Simple therapeutic strategies targeted at attenuating the progression of chronic low-grade inflammation and insulin resistance are urgently required to prevent or slow the development of type 2 diabetes in susceptible individuals.	25011647
Weight Gain, Inflammation, Skeletal muscle structure	Altered Intercellular Communication	Despite similar weight gain, subjects with smaller fat cells at baseline had a greater decrease in insulin sensitivity, which was linked with upregulated skeletal muscle tissue inflammation.	25011943
Inflammation, Units Of Measure - Siemens	Altered Intercellular Communication	Expression of genes involved in inflammation and tissue remodeling in VAT and liver showed a similar alteration pattern in MHO and MAO individuals.	25011950
Inflammation, Fibrosis Assessment, Phlebitis	Altered Intercellular Communication	More than 80 % of the left thyroid lobe was effaced by fibrosis and inflammation (lymphocytes, 57 IgG4+ plasma cells per 1 high-power field, an IgG4/IgG ratio of 0.67, and eosinophils) with extension into the surrounding tissues and occlusive phlebitis.	25011997
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Prevalence of inflammation and benign prostatic hyperplasia on autopsy in Asian and Caucasian men.	25012523
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Inflammation has been suggested to be involved in the pathogenesis of benign prostatic hyperplasia (BPH).	25012523
Inflammation	Altered Intercellular Communication	We correlated the presence and grade of acute inflammation (AI) or chronic inflammation (CI) and BPH.	25012523
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	In this study, we looked at the prevalence of inflammation and benign prostatic hyperplasia (BPH) on autopsy in Asian and Caucasian men.	25012523
Inflammation	Altered Intercellular Communication	We found chronic inflammation in>70% of men on autopsy.	25012523
Inflammation	Altered Intercellular Communication	More chronic inflammation was associated with more BPH.	25012523
Psychotic Disorders	Altered Intercellular Communication	An overactive striatal dopaminergic neurotransmission is described in psychosis and may be associated with a state of aberrant salience attribution.	25012755
Inflammation	Altered Intercellular Communication	Chronic inflammation was thought to be more important than the other existing plausible hypotheses in the course of TO.	25013916
Traumatic, Pneumonitis, Pneumonia	Altered Intercellular Communication	In addition, survival and pulmonary inflammation were measured in mice undergoing traumatic brain injury with or without pneumonia.	25014065
Inflammation, Atherosclerosis	Altered Intercellular Communication	Soluble urokinase plasminogen activator receptor (suPAR), a marker of inflammation, has been associated with subclinical atherosclerosis.	25014213
Inflammation, Primary Biliary Cholangitis, Immune-mediated, Intrahepatic bile duct	Altered Intercellular Communication	PBC is characterized by portal inflammation and immune-mediated destruction of intrahepatic bile ducts in liver histology and the presence of antimitochondrial antibodies in the serum of nearly 95% of patients.	25014239
Inflammation	Altered Intercellular Communication	Angiotensin receptor 1 blockade reduces secretion of inflammation associated cytokines from cultured human carotid atheroma and vascular cells in association with reduced extracellular signal regulated kinase expression and activation.	25016365
Inflammation, Atheroma	Altered Intercellular Communication	Our findings suggest that ATR1 blockade downregulates atheroma tissue ERK1/2 expression leading to a reduction in cytokine production and that a non-AII agonist ATR1 signalling response may induce expression of these inflammation associated cytokines in the atheroma.	25016365
Inflammation, Thoracic Injuries	Altered Intercellular Communication	High-mobility group box 1 (HMGB1), a key late mediator of systemic inflammation, is a potentially useful biomarker for predicting outcome in patients with severe blunt chest trauma.	25016440
Inflammation, Carcinogenesis, Adenomatous Polyps	Altered Intercellular Communication	It has been shown that local chronic inflammation may lead to colorectal carcinogenesis via adenomatous polyps.	25016780
Inflammation, Neoplasms	Altered Intercellular Communication	Tumor necrosing factor-alpha (TNF-alpha), interleukin-6 (IL-6) and C-reactive protein (CRP) are biomarkers of inflammation and indicators of the immune response to tumors.	25016780
Inflammation, Fibrosis Assessment, Tissue injury, Bronchiectasis	Altered Intercellular Communication	Th17 cells play a crucial role in neutrophilic inflammation and tissue injury in non-cystic fibrosis (non-CF) bronchiectasis.	25016929
Inflammation	Altered Intercellular Communication	This grading system offers a means of assessing the degree of inflammation and facilitates speculation about the duration of VKH disease.	25017008
Carcinoma	Altered Intercellular Communication	The mean age of patients with severe dysplasia/carcinoma and invasive carcinoma was significantly older than that of inflammation/hyperplasia (F = 6.773, P < 0.05) .	25017219
Squamous Hyperplasia, Inflammation, Dysplasia, Carcinoma	Altered Intercellular Communication	In 138 patients, 85 patients (61.6%) were pathologically diagnosed as chronic inflammation or squamous epithelium hyperplasia, 18 patients (13.0%) as mild dysplasia, 10 patients (7.2%) as moderate dysplasia, 15 patients (10.9%) as severe dysplasia/carcinoma in situ and 10 patients (7.2%) as invasive carcinoma.	25017219
Dysplasia	Altered Intercellular Communication	68.5% vocal folds with inflammation/hyperplasia showed nearly normal mucosal waves, and 72.7% to 80.0% vocal folds with moderate or more severe dysplasia showed severe reduced mucosal waves.	25017219
Inflammation, Ocular Hypertension, Edema, Cataract, Glaucoma, CTCAE	Altered Intercellular Communication	Control of inflammation, improvement of visual acuity (VA) to >= 20/40, improvement of VA loss attributed to macular edema (ME), incident cataract affecting VA, cataract surgery, ocular hypertension, and glaucoma surgery.	25017415
Delirium, Inflammation	Altered Intercellular Communication	A possible neuroinflammatory basis for delirium is likely and C-reactive protein (CRP) as a marker for inflammation can possibly play a predictive role.	25017770
Childhood Leiomyosarcoma, Arteritis	Altered Intercellular Communication	Histologic findings showed an arterial leiomyosarcoma combined with elements of arterial inflammation.	25017783
Airway structure, Wheezing, Nasal allergies, Rhinitis	Altered Intercellular Communication	We assessed whether airway inflammation markers were associated with nasal allergies and self-reported symptoms of wheeze and rhinitis in 130 children 6-12 year old in an epidemiological context.	25019424
allergic inflammation	Altered Intercellular Communication	In conclusion, FeNO and nasal tryptase reflect allergic inflammation in the respiratory system.	25019424
Inflammation, Hostility	Altered Intercellular Communication	Trait hostility is associated with systemic inflammation in married couples: an actor-partner analysis.	25019591
Inflammation, Hostility, Anger, Coronary heart disease	Altered Intercellular Communication	Trait anger and hostility predict the development of coronary heart disease, and systemic inflammation may partly mediate this association.	25019591
Inflammation, Impaired cognition, Depressed mood	Altered Intercellular Communication	Although it is well established that late-life depression is associated with both systemic low-graded inflammation and cognitive impairment, the relation between inflammation and cognition in depressed older persons is still equivocal.	25019974
Inflammation, Fibrosis Assessment, Granuloma	Altered Intercellular Communication	We sought to determine whether anti-TNF-a therapy affects histologic inflammation, fibrosis, and granuloma formation.	25022570
Inflammation, Granuloma	Altered Intercellular Communication	Compared with controls, the group treated with anti-TNF-a showed a reduction in mucosal and submucosal inflammation (P < .05), a decrease in granuloma formation (P < .05), and an increase in duplication of the muscularis mucosae (P < .05).	25022570
Inflammation, Fibrosis Assessment, Granuloma	Altered Intercellular Communication	Resection specimens from patients with CD treated with anti-TNF-a therapy showed (a) reduced mucosal and submucosal inflammation; (b) a decrease in granuloma formation; and (c) a distinct pattern of submucosal hyaline fibrosis, with increased fibrosis in the muscularis mucosae and muscularis propria.	25022570
Locally Advanced Unresectable Colorectal Adenocarcinoma	Altered Intercellular Communication	Inflammation-based prognostic scores and nutritional prognostic index in patients with locally-advanced unresectable colorectal cancer.	25022764
Inflammation, Periodontitis, Osteopenia	Altered Intercellular Communication	This leads to inflammation of the pulp (pulpitis), soft tissue breakdown, and finally to bone loss around the root apex (apical periodontitis).	25022970
Inflammation	Altered Intercellular Communication	Inflammation contributes to hemopoiesis by lowering responses to epoetin (EPO) and to an increase in the mortality of patients on hemodialysis.	25023457
Inflammation	Altered Intercellular Communication	However, nutritional status might alter associations among inflammation, EPO responsiveness, and the risk of mortality.	25023457
Stillbirth, Spontaneous abortion, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Pregnancy loss	Altered Intercellular Communication	Metabolic, hormonal, and hemostatic changes associated with pregnancy loss (stillbirth and miscarriage) may contribute to the development of cardiovascular disease (CVD) in adulthood.	25024237
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Synaptosomal-associated protein of 25 kDa (SNAP-25) is an age-regulated vesicular SNARE protein involved in the exocytosis of neurotransmitters from synapses, a process that is altered in Alzheimer's disease (AD).	25024311
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	To investigate pro-atherosclerotic markers (endothelial dysfunction and inflammation) in patients one year after liver transplantation.	25024624
Swelling, Telangiectasis	Altered Intercellular Communication	At each visit, patients were evaluated for redness, swelling, wound healing, scar formation, tissue inflammation/atrophy, telangiectasis, and pigmentary disturbances.	25025385
Granulomatous inflammation, Necrosis, Pauci-Immune Glomerulonephritis - Renal Limited	Altered Intercellular Communication	A nephrectomy was performed that demonstrated a discrete lesion with extensive necrosis, granulomatous inflammation, and crescentic pauci-immune glomerulonephritis, findings consistent with GPA.	25025447
Inflammation, cyclosporine, Endothelial dysfunction, Angina Pectoris, Variant	Altered Intercellular Communication	Patients with coronary spastic angina (CSA) also have endothelial dysfunction and inflammation.	25025992
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Activation of PPAR-g improves endothelial dysfunction and inflammation.	25025992
Inflammation, glycation	Altered Intercellular Communication	Advanced glycation end products (AGEs) may promote inflammation by interacting with the receptor for advanced glycation end products.	25026914
Inflammation, Periodontal Diseases, Diabetes Mellitus	Altered Intercellular Communication	Periodontal disease is related to aging, smoking habits, diabetes mellitus, and systemic inflammation.	25026916
Xanthogranulomatous inflammation, Granulomatous Endometritis, Xanthogranulomatous salpingitis, Endometritis	Altered Intercellular Communication	Although xanthogranulomatous endometritis and xanthogranulomatous salpingitis of the female genital tract has been described previously, to the best of our knowledge, this is the first report of xanthogranulomatous inflammation with infiltration into the uterine myometrium from the perimetrium without endometritis.	25027857
Xanthogranulomatous inflammation	Altered Intercellular Communication	Histopathological findings revealed that the abscess was caused by xanthogranulomatous inflammation with the granulation tissue and chronic inflammatory cells that consisted of focal and sheets of foam cells.	25027857
Inflammation, Xanthoma	Altered Intercellular Communication	The inflammation destroyed the perimetrial elastic lamina, and the myometrium was deeply infiltrated by the xanthoma cells.	25027857
Salpingitis, Endometritis	Altered Intercellular Communication	Neither endometritis nor salpingitis was coexistent with the xanthogranulomatous inflammation.	25027857
Xanthogranulomatous inflammation	Altered Intercellular Communication	The patient was diagnosed as xanthogranulomatous inflammation, most likely arising from the perimetrium.	25027857
Inflammation, Left ventricular systolic dysfunction, Fluid overload	Altered Intercellular Communication	These are linked to the pathophysiological mechanisms pertaining to left ventricular systolic dysfunction and remodeling, systemic inflammation and volume overload.	25027873
Inflammation, Anemia, Fluid overload	Altered Intercellular Communication	Increased myocardial remodeling, inflammation, and volume overload are the hallmarks of patients with anemia and HF.	25027873
methyldopa, Inflammation	Altered Intercellular Communication	Inflammation, among many factors, has been suggested to play an important role in AMD pathogenesis.	25028103
Refractory anemias, Inflammation, Arthritis	Altered Intercellular Communication	Although patients with RA had higher scores of MRI inflammation and ACPA-positive patients had more BME, the severity of MRI inflammation assessed according to RAMRIS does not accurately differentiate patients with RA from other early arthritis patients.	25028382
Inflammation, Atrophic	Altered Intercellular Communication	Unlike pepsinogen II and pepsinogen I to II ratio that were affected by the severity of inflammation and atrophy in corpus in all groups, pepsinogen I generally did not change.	25028655
Inflammation, Fever, CTCAE	Altered Intercellular Communication	From the clinical and laboratory data investigated, 53.33% of the cases presented with fever, and all except one patient presented with increased measures in inflammation tests.	25029577
Communicable Diseases, Inflammation, Mucosal erosion	Altered Intercellular Communication	The rates of mucosal erosion and active inflammation with the presence of pure coccoid HP infection were 36.0% (9/25) and 44.0% (11/25), respectively, both higher than those without HP infection (13.5%, 10/74; 24.3%, 18/74), while lower than those infected with spiral HP (72.1%, 49/68; 79.4%, 54/68).	25030866
Communicable Diseases, Inflammation	Altered Intercellular Communication	The quantity of interstitial lymphocyte and inflammation severity were also higher than those without HP infection, while lower than those with spiral HP infection.	25030866
Synovial joint structure	Altered Intercellular Communication	Crystal presence is an obvious prerequisite for possible crystal induced-inflammation in these tissues, just as similar crystals elicit a gouty inflammatory cascade in synovial joints.	25031195
Klinefelter Syndrome, Trigonitis	Altered Intercellular Communication	Pseudomembranous trigonitis in a male with Klinefelter syndrome: a case report and evidence of a hormonal etiology.	25031763
Inflammation, Electrocardiogram: myocardial infarction (finding), Cerebrovascular accident, Peripheral Vascular Diseases, Dental Plaque	Altered Intercellular Communication	Inflammation promotes plaque instability and clinical disease, such as myocardial infarction, stroke and peripheral vascular disease.	25032953
Tumor necrosis, Inflammation, Atherosclerosis	Altered Intercellular Communication	Activation of CD137 (tumor necrosis factor receptor super family 9) promotes inflammation and disease development in murine atherosclerosis.	25032953
Inflammation, Gastritis	Altered Intercellular Communication	Although severe gastritis was not observed, activity and inflammation were significantly higher in patients positive for H. pylori than in patients negative for H. pylori.	25034254
ARCN1 gene, Chronic Obstructive Airway Disease, Tissue injury, Pneumonitis	Altered Intercellular Communication	Cigarette smoking is the main cause of chronic obstructive pulmonary disease (COPD) inducing oxidative stress and local tissue injury, resulting in pulmonary inflammation.	25034386
vascular inflammations, Vasculitis, CTCAE	Altered Intercellular Communication	Widespread vascular inflammation in a patient with antineutrophil cytoplasmic antibody-associated vasculitis as detected by positron emission tomography.	25034437
Clinical Events Domain, Coronary Arteriosclerosis	Altered Intercellular Communication	We undertook this study to determine the presence and levels of adhesion molecules as well as other inflammation-related markers and evaluate their invasive angiography findings to compare between patients with CE or atherosclerotic coronary artery disease (CAD).	25034460
Inflammation, Affection	Altered Intercellular Communication	The presence of high levels of these molecules, along with not uncommon multivessel and extensive coronary affection suggest the participation of subclinical inflammation, which may have an important role in the development of CE.	25034460
Inflammation, Gastrointestinal perforation	Altered Intercellular Communication	The electrocardiogram, esophagogram, and chest computed tomographic scan commonly revealed pericardial fluid and air and excluded a gastrointestinal perforation in late stage of severe inflammation.	25034497
Inflammation, Chronic thromboembolic pulmonary hypertension	Altered Intercellular Communication	Chronic thromboembolic pulmonary hypertension (CTEPH) is associated with chronic inflammation but the pathological mechanisms are largely unknown.	25034560
Inflammation, Fever, CTCAE	Altered Intercellular Communication	The newborn became touch-sensitive, cried a lot, had worsening laboratory test results, and increased inflammation parameters, but no fever was observed.	25035097
ARCN1 gene	Altered Intercellular Communication	The ratio of sputum-to-serum levels of H2S may provide a useful marker of COPD indicative of obstructive neutrophilic inflammation and of potential ongoing exacerbation.	25035127
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Inflammation has been proposed as the main cause for the high risk of atherosclerotic disease in DM II.	25035341
Inflammation, Fibrous	Altered Intercellular Communication	In this study, we compared markers of inflammation and fibrous repair in plaques from subjects with and without DM II.	25035341
Rupture, vascular inflammations, atherosclerotic	Altered Intercellular Communication	This study suggests that atherosclerotic plaques in subjects with DM II are more prone to rupture because of impaired repair responses rather than to increased vascular inflammation.	25035341
Inflammation, Premenstrual syndrome	Altered Intercellular Communication	Association of inflammation markers with menstrual symptom severity and premenstrual syndrome in young women.	25035435
Inflammation, POLYDACTYLY, POSTAXIAL, WITH PROGRESSIVE MYOPIA, Premenstrual syndrome	Altered Intercellular Communication	Are markers of chronic inflammation associated with menstrual symptom severity and premenstrual syndrome (PMS)?	25035435
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Chronic inflammation has been implicated in the etiology of depression and other disorders that share common features with PMS, but whether inflammation contributes to menstrual symptom severity and PMS is unknown.	25035435
Inflammation	Altered Intercellular Communication	7-Ketocholesterol-induced inflammation signals mostly through the TLR4 receptor both in vitro and in vivo.	25036103
Inflammation, Lipoproteins	Altered Intercellular Communication	It is suspected of causing chronic inflammation in tissues exposed to oxidized lipoprotein deposits.	25036103
Inflammation	Altered Intercellular Communication	Our results indicate that 7KCh-induced inflammation is mediated mostly though the TLR4 receptor with some cross-activation of EGFR-related pathways.	25036103
Inflammation	Altered Intercellular Communication	The 7KCh-induced inflammation also seems to involve a robust ER stress response.	25036103
Cell Death, Inflammation	Altered Intercellular Communication	Female gene expression was associated with cell death and survival, cell-cell signaling and inflammation.	25036109
Cell Death, Inflammation	Altered Intercellular Communication	Female gene expression was associated with cell death and survival, cell-cell signaling and inflammation.	25036109
Inflammation, Dental Plaque	Altered Intercellular Communication	Serum high-sensitivity C-reactive protein (hs-CRP) is a sensitive indicator of inflammation, which is closely related with the progress of plaque formation.	25036169
Inflammation, Infection associated with prosthesis of left hip joint	Altered Intercellular Communication	(18)F-fluorodeoxy glucose and (18)F fluoride PET for detection of inflammation focus in periprosthetic hip joint infection cases.	25036230
Myelitis	Altered Intercellular Communication	Cervical spinal cord inflammation was the most common.	25036359
Inflammation, Dacryocystitis, Bacterial Infections	Altered Intercellular Communication	Dacryocystitis is a common inflammation of the lacrimal sac, usually from an underlying bacterial infection.	25036545
Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain and function proved to be predictors of the outcome while some measures of inflammation were not.	25036855
Intraocular inflammation	Altered Intercellular Communication	A 15-year-old Hispanic girl was referred for bilateral intraocular inflammation.	25037015
Inflammation, Renal function	Altered Intercellular Communication	Baseline plasma concentrations of 25(OH)D and biomarkers of liver and kidney functions and inflammation were measured.	25037556
Inflammation, Intact	Altered Intercellular Communication	Activation of TLR9 signaling in the pocket epithelium was highly associated with periodontal inflammation and possibly with loss of tissue integrity.	25037760
HD Term Type, Inflammation	Altered Intercellular Communication	Circulating gelsolin can modulate inflammation and is correlated with HD mortality.	25039281
Fibrosis Assessment	Altered Intercellular Communication	Mesenchymal stromal cells (MSC), a key component of the stem cell niche in bone marrow and possibly other organs including lung, have been shown to enhance epithelial repair and are effective in preclinical models of inflammation-induced pulmonary fibrosis, but may be profibrotic in some circumstances.	25039426
Inflammation, Periodontal Diseases	Altered Intercellular Communication	It is important to address this deficiency in our knowledge as neutrophils are the primary immune cell present in the crevicular fluid and oral environment and previous work has suggested that they may be good indicators of overall oral inflammation and periodontal disease severity.	25040400
Inflammation, Epithelial cell abnormality	Altered Intercellular Communication	Cervical cytological screening results of 8,495 cases in Turkey--common inflammation but infrequent epithelial cell abnormalities?	25040962
Inflammation, Squamous Epithelial Cells	Altered Intercellular Communication	The most common diagnosis was found to be inflammation, 65.5 % (5,566 out of 8,495), and the least was squamous epithelial abnormalities 0.2% (13 out of 8,495).	25040962
vinyltriethoxysilane	Altered Intercellular Communication	Median pre-chemotherapy NLR (p = 0.015) and PLR (p = 0.040) were significantly higher in patients with intermediate risk class who developed symptomatic VTE with a twofold increased VTE risk for both inflammation-based markers (NLR: p = 0.022; PLR: p = 0.037) and a worst 1-year VTE-free survival for patients with high NLR or PLR.	25042739
Inflammation, Thrombosis	Altered Intercellular Communication	Durable polymer has been linked with persistent inflammation of vessel wall and delayed endothelial healing that may increase the risk of late and very late stent thrombosis.	25043067
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Peroxisome proliferator-activated receptors (PPARs) are transcriptional factors involved in several biological processes such as inflammation, cancer growth, progression and apoptosis that are important in lung and upper aero-digestive tract (UADT) cancer outcomes.	25043640
Inflammation, Epilepsy	Altered Intercellular Communication	Inflammation is a substantial indicator of epilepsy risk.	25043754
Inflammation, Acute and chronic inflammation	Altered Intercellular Communication	In 23%, the diagnosis was an acute inflammation (presence of granulocytes); in 33%, chronic active inflammation (presence of T lymphocytes); in 33%, low-grade inflammation (presence of CD68 cells, without T lymphocytes); and in 3%, a malignant process.	25043793
Inflammation, Myocardial	Altered Intercellular Communication	Inflammation and myocardial damage markers influence loss of residual renal function in peritoneal dialysis patients.	25043805
Inflammation, Cardiovascular system, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Evaluations included measurements of residual renal function, dialysis adequacy parameters, cardiovascular comorbidity, and measurements of biochemical markers of cardiovascular disease (CVD) and inflammation, as well as resting electrocardiography.	25043805
Retinal Detachment, Inflammation, Macular Edema, Cystoid	Altered Intercellular Communication	There were no postlaser complications such as increased intraocular pressure (IOP), severe inflammation, cystoid macular edema, or retinal detachment.	25044140
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Improvement in vitamin D status does not improve insulin resistance, blood pressure, inflammation or HbA1c, but might increase insulin secretion in patients with established type 2 diabetes.	25044176
Inflammation, Retinal Diseases, Endothelial dysfunction	Altered Intercellular Communication	Low-grade inflammation and endothelial dysfunction explain the association between retinopathy and left ventricular ejection fraction in men: an 8-year follow-up of the Hoorn Study.	25044234
Inflammation	Altered Intercellular Communication	Microvascular endothelial dysfunction ([ED] b -4.87 95% CI -13.40 to 3.67) and low-grade inflammation ([LGI] b -5.30 95% CI -13.72 to 3.12) both diminished the association.	25044234
Inflammation, hepcidin	Altered Intercellular Communication	Patients with inflammation respond less well to treatment with erythropoietin, possibly because the increased production of hepcidin reduces the availability of iron for hematopoiesis.	25044383
Inflammation, Carcinogenesis	Altered Intercellular Communication	In the CCA-hamsters, STATs expression was gradually increased along the carcinogenesis, especially at 30 days post-infection in which the inflammatory response was markedly observed, showing the correlation between the inflammation and STATs activation.	25044480
Inflammation, Carcinogenesis, FBN2 wt Allele	Altered Intercellular Communication	STAT3 is the major STAT, which plays roles in the inflammation that contributes to CCA carcinogenesis and progression and may serve as a marker for a poor prognosis of CCA.	25044480
Inflammation, Injury of kidney	Altered Intercellular Communication	Inflammation is an important factor in renal injury.	25045297
Refractory anemias, Inflammation	Altered Intercellular Communication	We found no association between REE and disease activity in RA patients, implying that energy metabolism in RA patients might be independent of RA-associated systemic inflammation.	25045300
Inflammation, Periodontitis, Atherosclerosis, Endothelial dysfunction, physiopathological	Altered Intercellular Communication	Oral inflammation, such as periodontitis, can lead to endothelial dysfunction, accelerated atherosclerosis, and vascular dysfunction.	25045683
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Egg intake during carbohydrate restriction alters peripheral blood mononuclear cell inflammation and cholesterol homeostasis in metabolic syndrome.	25045936
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	We further sought to determine whether egg yolk intake affects peripheral blood mononuclear cell (PBMC) inflammation and cholesterol homeostasis in MetS, as HDL and its associated lipid transporter ATP-binding cassette transporter A1 (ABCA1) reduce the inflammatory potential of leukocytes through modulation of cellular cholesterol content and distribution.	25045936
Granulomatous inflammation, Fibrosis Assessment, Infection	Altered Intercellular Communication	Imaging always identified dermal fillers in the oral region, distinguishing among infections, fibrosis, granulomatous inflammation and product migration.	25046237
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Vitamin D is a multi-functional immune regulator, and a low serum concentration of vitamin D promotes autoimmune inflammation.	25046415
Inflammation, Atherosclerosis	Altered Intercellular Communication	CD14 is a predictor of inflammation and associated with atherosclerosis.	25046588
Inflammation, Ischemic, Ischemia	Altered Intercellular Communication	Our findings highlight the key significance of inflammation in the early response to ischaemia during the transitory ischaemic episode.	25046654
Vaginitis	Altered Intercellular Communication	They were also more likely to show microscopic evidence of vaginal inflammation and vaginitis.	25046810
Inflammation	Altered Intercellular Communication	AMP-activated protein kinase (AMPK) inhibits chondrocyte procatabolic responses to inflammation and biomechanical injury.	25047750
Osteomyelitis, Inflammation, Bone necrosis	Altered Intercellular Communication	Patient records were searched for inflammatory conditions including unspecified inflammation, osteomyelitis, osteonecrosis due to drugs, and other osteonecrosis.	25047929
Osteomyelitis, Inflammation, Bone necrosis	Altered Intercellular Communication	Patient records were searched for inflammatory conditions including unspecified inflammation, osteomyelitis, osteonecrosis due to drugs, and other osteonecrosis.	25047929
Inflammation, Necrosis	Altered Intercellular Communication	Pathological examination revealed the presence of necrosis and chronic inflammation.	25048049
Inflammation	Altered Intercellular Communication	In conclusion, underweight status after treatment may be a poor prognostic factor in patients with advanced-stage ovarian cancer, which accompanies increased host inflammation and decreased immunity.	25050383
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Impact of Supplementation with Curcuminoids on Systemic Inflammation in Patients with Knee Osteoarthritis: Findings from a Randomized Double-Blind Placebo-Controlled Trial.	25050518
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Osteoarthritis (OA) is a degenerative joint disease associated with inflammation.	25050518
Autoimmune Diseases, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis a chronic inflammatory autoimmune disease with inflammation of the joint, leading to damage of bone and surrounding cartilage.	25050521
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Cardiovascular disease is the leading cause of mortality in hemodialysis patients and is associated with chronic inflammation.	25051062
Inflammation, Heart failure, Sarcopenia, Myocardial fibrosis, Hypertensive disease	Altered Intercellular Communication	In order to establish the prognostic value of age-related pathogenesis and the development of heart failure related to lipid peroxidation, endogenous subclinical inflammation, apoptosis, sarcopenia, interstitial myocardial fibrosis in the risk of mortality and survival rates, for the first time the results of echocardiography, enzyme immunoassay, bioimpedansmetry with the scale of the Seattle model of heart failure performed in 84 elderly patients with arterial hypertension stage II (middle age 68,3 +/- 1,8 years) were compared.	25051770
Inflammation, Periprosthetic osteolysis	Altered Intercellular Communication	Wear debris-induced inflammation is considered to be the main cause for periprosthetic osteolysis in total hip replacements (THR).	25051953
Osteolysis	Altered Intercellular Communication	Our findings indicate that wear particles of different chemical composition induced similar inflammatory responses, which suggests that particle size and load might be more important than the wear particle composition in periprosthetic inflammation and osteolysis.	25051953
Airway structure, Allergic, Asthma	Altered Intercellular Communication	Pollen exposure of allergic subjects with asthma causes increased nitric oxide (NO) in exhaled air (FENO) suggestive of increased airway inflammation.	25052059
Inflammation, Asthma	Altered Intercellular Communication	The aim of the present investigation was to analyze the relationship between central and peripheral components of FENO to clarify the distribution of pollen induced inflammation in asthma.	25052059
Allergic asthma, Airway structure	Altered Intercellular Communication	The findings may indicate that subjects with allergic asthma have airway inflammation without alveolar involvement outside the pollen season and pollen exposure causes a further increase of airway inflammation and in a few subjects obstruction of intra acinar airways causing impeded back diffusion.	25052059
Inflammation, Sacroiliac joint structure, Spondylarthritis	Altered Intercellular Communication	The aim of this study was to describe the use of (99m)Tc-anti-TNF-a scintigraphy for detecting inflammation of the sacroiliac joints in a patient with non-radiographic axial spondyloarthritis.	25052689
Inflammation, Morning stiffness - joint, Uveitis	Altered Intercellular Communication	A 47-year-old female patient, non-smoker and non-drinker, complained of a low back pain inflammation, which began 4 years before her condition have exacerbated to morning stiffness and anterior uveitis in the last 6 months.	25052689
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Advanced glycation end products (AGEs) accumulate in T2DM, resulting in inflammation, oxidative stress, and protein cross-linking, which are known contributors to neurodegeneration.	25053588
Airway structure, ARCN1 gene	Altered Intercellular Communication	Characterization of airway inflammation in patients with COPD using fractional exhaled nitric oxide levels: a pilot study.	25053884
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	To characterize fractional exhaled nitric oxide (FeNO) levels that may be indicative of Th2-mediated airway inflammation in patients with chronic obstructive pulmonary disease (COPD).	25053884
Airway structure, ARCN1 gene	Altered Intercellular Communication	Since FeNO is useful for identifying patients with airway inflammation who will have a beneficial response to treatment with an inhaled corticosteroid, these data may have important implications for the management of COPD patients.	25053884
Inflammation, Carcinogenesis, Neoplasms	Altered Intercellular Communication	Mounting evidence supports that chronic inflammation (such as chronic overactivation of IL-1 system) is a crucial event in carcinogenesis and tumor progression.	25054228
Glioblastoma Multiforme Pathway	Altered Intercellular Communication	While much attention is paid to specific anti-tumor immunity, little is known about the role of chronic inflammation/innate immunity in glioma pathogenesis.	25054228
Carcinoma of lung, Toxic effect	Altered Intercellular Communication	Inflammation-related genetic variants predict toxicity following definitive radiotherapy for lung cancer.	25054431
Esophagitis, Radiation Pneumonitis	Altered Intercellular Communication	We therefore conducted a pathway-based analysis to identify inflammation-related single-nucleotide polymorphisms associated with radiation-induced pneumonitis or esophagitis.	25054431
Toxic effect	Altered Intercellular Communication	We concluded that inflammation-related genetic variants could contribute to the development of radiation-induced toxicities.	25054431
Dose-Limiting, Toxic effect	Altered Intercellular Communication	However, radiation-induced toxicities (pneumonitis/esophagitis) are common dose-limiting inflammatory conditions.	25054431
Inflammation, neurological complication	Altered Intercellular Communication	H1N1 vaccination can result in important neurological complications probably secondary to post-vaccination inflammation.	25054980
Pain Distress Question, Inflammation, Neoplasms, Malignant neoplasm of skin, Perineural spread, Ulceration, CTCAE	Altered Intercellular Communication	Itch and pain associated with skin cancer at the time of excision ranked on an 11-point (score range, 0-10) numerical visual analog scale and histopathologic analysis for each neoplasm (assessment of the amount and type of inflammation, ulceration, perineural invasion, and depth of invasion).	25055194
Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain intensity was significantly associated with the degree of inflammation (mild or none vs moderate or marked; P < .001), presence of neutrophils in the inflammatory infiltrate (predominantly mononuclear vs mixed or neutrophilic; P = .003), presence of eosinophils (present vs absent; P = .007), ulceration (yes vs no; P = .003), perineural invasion (yes vs no; P < .001), depth of invasion (P = .001), and largest diameter length of skin lesion (P < .003).	25055194
Inflammation	Altered Intercellular Communication	Several published studies suggest that physical activity is a beneficial nonpharmacological intervention to reduce chronic inflammation.	25055246
Inflammation, Atherosclerosis	Altered Intercellular Communication	The hallmark of atherosclerosis is chronic inflammation in the vessel wall.	25056169
Inflammation	Altered Intercellular Communication	Midkine, a multifunctional cytokine, fulfils different roles in inflammation and promotion of neoangiogenesis.	25056169
Inflammation, Hypertension, CTCAE, Traumatic injury	Altered Intercellular Communication	The glomerulus contains well-developed capillaries, which are at risk of injury due to high hydrostatic pressure, hyperfiltration, hypertension and inflammation.	25056826
Inflammation, Carcinogenesis	Altered Intercellular Communication	Chronic inflammation is known to be one of the main steps in carcinogenesis.	25057172
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Identification of those with chronic inflammation may help identify subjects at risk of cancer.	25057172
Inflammation, Atherosclerosis	Altered Intercellular Communication	A crucial role for CDC42 in senescence-associated inflammation and atherosclerosis.	25057989
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Risk factors for atherosclerosis accelerate the senescence of vascular endothelial cells and promote atherogenesis by inducing vascular inflammation.	25057989
Inflammation	Altered Intercellular Communication	We identified CDC42 signaling as a mediator of chronic inflammation associated with endothelial senescence.	25057989
Inflammation, Dental Plaque, atherosclerotic	Altered Intercellular Communication	Likewise, endothelial-specific deletion of Cdc42 significantly attenuated chronic inflammation and plaque formation in atherosclerotic mice.	25057989
Inflammation	Altered Intercellular Communication	While inhibition of NF-kB suppressed the pro-inflammatory responses in acute inflammation, the influence of Cdc42 deletion was less marked.	25057989
Inflammation	Altered Intercellular Communication	These findings indicate that the CDC42 pathway is critically involved in senescence-associated inflammation and could be a therapeutic target for chronic inflammation in patients with age-related diseases without compromising host defenses.	25057989
Inflammation	Altered Intercellular Communication	Repetitive microtrauma within the pes anserinus may lead to chronic inflammation and later result in development of degenerative changes in this region.	25058106
Inflammation, FBN2 wt Allele	Altered Intercellular Communication	CCA arises via chronic inflammation which may be associated with autoantibodies production.	25058392
allergic inflammation	Altered Intercellular Communication	Hence, the activation of apical TLR9 on IECs, potentially by microbiota-derived signals, may play an important role in the prevention of allergic inflammation.	25058467
Inflammation, Psoriasis, Eczema	Altered Intercellular Communication	We observed a strong clinical inflammation with a mixed psoriasis and eczema phenotype in histology.	25058585
Inflammation, talc	Altered Intercellular Communication	Predictive value of systemic and local inflammation parameters in talc pleurodesis assessment.	25059234
Fibrosis Assessment	Altered Intercellular Communication	Then, we assessed the efficacy of MR16-1 in tight skin-1 (Tsk-1) mice, an inflammation-independent model of skin fibrosis.	25059342
Inflammation, Thrombosis	Altered Intercellular Communication	The safety of drug-eluting stents (DES) vs. bare metal stents (BMS) in the perioperative setting, a heightened state of inflammation and thrombosis is not well defined.	25059742
Inflammation, Dissection of aorta, Data types - Address	Altered Intercellular Communication	Inflammation has been reported to be associated with aortic dissection (AD), from the development to the prognosis of AD.	25059935
Inflammation	Altered Intercellular Communication	The inflammation associated with DNM may involve the heart, which produces acute changes in the electrocardiogram (ECG).	25060009
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Pepsinogen levels in plasma are increased by inflammation in the gastric mucosa, including inflammation resulting from Helicobacter pylori infection.	25060199
Inflammation, Allergic rhinitis (disorder)	Altered Intercellular Communication	Allergic fungal rhinosinusitis (AFRS) is a disease demonstrating substantial eosinophilic inflammation and characteristic radiographic bony erosion/expansion.	25060295
Hemorrhage	Altered Intercellular Communication	Physical, histological and endoscopic examination revealed neither focus of active bleeding nor signs of active inflammation.	25060698
Inflammation, Myocardial Ischemia	Altered Intercellular Communication	Reciprocal effects of systemic inflammation and brain natriuretic peptide on adiponectin biosynthesis in adipose tissue of patients with ischemic heart disease.	25060790
Inflammation, Myocardial Ischemia	Altered Intercellular Communication	To explore the role of systemic inflammation in the regulation of adiponectin levels in patients with ischemic heart disease.	25060790
Inflammation, Atherosclerosis	Altered Intercellular Communication	This study demonstrates the regional variability in the responsiveness of human adipose tissue to systemic inflammation and suggests that BNP (not systemic inflammation) is the main driver of circulating adiponectin in patients with advanced atherosclerosis even in the absence of HF.	25060790
Airway structure	Altered Intercellular Communication	Asthma management in an outpatient setting is best accomplished by clinical evaluation coupled with spirometry and symptom evaluation, but these assessments do not provide information about airway inflammation.	25060819
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide (fraction of exhaled nitric oxide [FeNO]) measures T-helper cell type 2-mediated airway inflammation and may be a useful adjunct in asthma management.	25060819
Airway structure	Altered Intercellular Communication	Without FeNO, the clinician's assessment of airway inflammation was incorrectly classified in 50% of subjects.	25060819
Airway structure, Asthma	Altered Intercellular Communication	Measurement of FeNO augments routine clinical assessment of asthma by measuring airway inflammation.	25060819
Inflammation, Diabetes Mellitus, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation and oxidative stress appear to play some role in the mechanisms underlying aging, diabetes, cardiovascular disease, and other complications of diabetes.	25060886
Intraocular inflammation	Altered Intercellular Communication	Control of intraocular inflammation, defined as complete lack of clinical and angiographic signs of inflammatory activity, was achieved in 16 of 24 patients (67%).	25061107
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The association between cardiopulmonary reserve and inflammation was tested by multivariable regression analysis with covariates including anaerobic threshold (AT) and malignancy.	25061264
Inflammation, Heart failure	Altered Intercellular Communication	Poor exercise capacity in patients without a diagnosis of heart failure is independently associated with markers of inflammation.	25061264
Inflammation	Altered Intercellular Communication	These observations suggest that preoperative inflammation associated with impaired cardiorespiratory performance may contribute to the pathophysiology of postoperative outcome.	25061264
Inflammation of orbit	Altered Intercellular Communication	Thus, the pathogenesis of GD and GO may correlate with different genetic backgrounds, which has been confirmed by studies of correlations between GO and polymorphisms in cytokines involved in orbit inflammation.	25061884
Inflammation	Altered Intercellular Communication	These findings suggest that inflammation plays a possible role in the pathophysiology of RHTN.	25061978
Inflammation, Metabolic Syndrome X, Cyclophosphamide/Vincristine/Dacarbazine Regimen, ETV3 wt Allele, Diabetes Mellitus	Altered Intercellular Communication	The Metabolic Syndrome, (MetS) a global epidemic, is a state of low grade chronic inflammation and confers an increased risk for diabetes and CVD.	25063948
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, ETV3 wt Allele, Diabetes Mellitus	Altered Intercellular Communication	Thus, we make the novel observation that sCD14 reflects increased monocyte TLR4 protein and activity in nascent MetS and by contributing to increased cellular inflammation could explain, in part, the increased risk for diabetes and CVD.	25063948
Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Inflammation, Fatty degeneration	Altered Intercellular Communication	Pirfenidone for two years benefits CHC patients and improves inflammation, fibrosis and steatosis in higher number of patients as previously shown for 12-months treatment with PFD.	25064094
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Emerging evidence indicates that low-grade inflammation is part of the clinical picture of OA and that there is a need to identify soluble biomarkers of ongoing inflammation in the joint from a translational aspect.	25065008
Vasculitis, Vasculitis, CTCAE	Altered Intercellular Communication	Cutaneous vasculitis (CV) encompasses a wide group of entities characterized by inflammation of skin blood vessels.	25065012
Inflammation, Carcinogenesis	Altered Intercellular Communication	Systemic inflammation plays an important role in the initiation, promotion, and progression of lung carcinogenesis.	25065540
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Expression analysis of miRNAs was performed by qPCR, and they were analysed for differences between patient gender and age, genotypes, stage of fibrosis, grade of inflammation, serum level of liver enzymes, serum viral load, the presence of steatosis and mode of transmission.	25065618
Inflammation, Chronic Kidney Diseases, Obesity	Altered Intercellular Communication	To investigate the relative associations of renal function, obesity, and inflammation with serum leptin levels in children with chronic kidney disease (CKD).	25066063
Inflammation, Diabetic Retinopathy	Altered Intercellular Communication	Chronic inflammation has a role in the pathogenesis of diabetic retinopathy.	25066224
Communicable Diseases, Inflammation	Altered Intercellular Communication	Infection with intracellular organisms may incite chronic inflammation.	25066224
Inflammation	Altered Intercellular Communication	MRI examination revealed no changes in the painful region in a majority of patients with AO, suggesting that inflammation was not present.	25068217
Airway structure	Altered Intercellular Communication	In conclusion, sputum IL-6 and IL-8 may play a role in neutrophilic airway inflammation seen in patients undergoing HSCT.	25068427
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Further studies should determine if chronic, dysregulated inflammation may accelerate hypertension in this population.	25070128
Uremia, Inflammation, Chronic Kidney Diseases, Vascular lesions	Altered Intercellular Communication	Our results indicate that sclerostin levels are elevated in CKD patients and are associated with inflammation, vascular lesions, uremia and (potentially) mortality.	25070604
Inflammation, Necrosis	Altered Intercellular Communication	The pancreas was divided into head, body, and tail, and each segment was classified according to image features: pattern 1, normal; pattern 2, mild inflammation; and pattern 3, necrosis.	25070771
Inflammation, Juvenile polyposis syndrome	Altered Intercellular Communication	Serum C-reactive protein (CRP) is a general marker of inflammation, and recent studies suggest that measurement of CRP in synovial fluid may be a more accurate method for diagnosing periprosthetic joint infection (PJI).	25070920
Inflammation, Bacterial Infections	Altered Intercellular Communication	Upregulated CD64 expression on neutrophils is the most useful marker for acute bacterial infections and systemic inflammation.	25071912
polychondritis, Orbital Pseudotumor	Altered Intercellular Communication	This led to rapid improvement in orbital symptoms and signs, and a diagnosis of specific orbital inflammation secondary to relapsing polychondritis was made.	25072220
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Intraoperative near-infrared imaging can distinguish cancer from normal tissue but not inflammation.	25072388
Vasculitic Ulcer	Altered Intercellular Communication	Thirty-four patients affected by other than vascular ulcers, neoplastic or inflammatory conditions, were excluded.	25072681
Inflammation, Pleural effusion disorder	Altered Intercellular Communication	The capillary leaks secondary to inflammation result in a larger pleural pore-size, which allows the large-sized lipoproteins to accumulate in exudative pleural effusions.	25072840
Inflammation, Nephritis	Altered Intercellular Communication	Low pre-transplant serum MBL levels are associated with more severe inflammation and increased apoptosis in early surveillance renal allograft biopsies suggesting that MBL modulates renal inflammation after transplantation.	25073029
Inflammation, Fever, CTCAE, Autosomal recessive inheritance, Brucellosis, Familial Mediterranean Fever	Altered Intercellular Communication	Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurrent episodes of fever and serosal, synovial, or cutaneous inflammation, caused by a dysfunction of pyrin as a result of mutation within the MEFV gene.	25073670
Communicable Diseases, Inflammation	Altered Intercellular Communication	Although tattooing is widely used and relatively safe, the presented case indicates the risk of infection or inflammation by tattooing.	25073671
Inflammation, Fatty degeneration	Altered Intercellular Communication	Elevated ferritin levels pointed to a higher incidence of steatosis (48 vs. 10% for normal ferritin, p < 0.001) and inflammation (87 vs. 62% for normal ferritin, p = 0.004).	25074257
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Elevated AST and ferritin levels were associated with steatosis, inflammation and fibrosis on liver biopsies.	25074257
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We evaluated circulating S100A12 and sRAGE in relation to clinical characteristics, nutritional status, inflammation and mortality risk in chronic kidney disease (CKD) Stage 5 patients starting on dialysis.	25074436
Inflammation, Comorbidity	Altered Intercellular Communication	Furthermore, S100A12 correlated with high-sensitivity C-reactive protein (hsCRP) levels (r = 0.53; P < 0.001) and a 1-SD higher level of S100A12 associated with increased all-cause mortality risk (hazard ratio 1.32, 95% confidence interval 1.01-1.73) after adjustment for age, sex, comorbidity, nutritional status and inflammation (hsCRP).	25074436
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	In CKD 5 patients, an increased concentration of S100A12 are associated with inflammation, comorbidities and increased mortality risk whereas no such associations were observed for sRAGE.	25074436
Inflammation	Altered Intercellular Communication	Oxidative stress and systemic inflammation as modifiers of cardiac autonomic responses to particulate air pollution.	25074558
Inflammation, Autonomic nervous system disorders	Altered Intercellular Communication	The role of oxidative stress and systemic inflammation on the association between personal exposures to ambient fine particulate matter <= 2.5 mm in diameter (PM2.5) and cardiac autonomic dysfunction, indicated by reduction in heart rate variability (HRV), has not been examined.	25074558
Inflammation	Altered Intercellular Communication	MRI-detected subclinical joint inflammation is associated with radiographic progression.	25074691
Inflammation, Arthritis	Altered Intercellular Communication	We recently demonstrated that MRI inflammation is prevalent in clinically non-swollen joints of early arthritis patients.	25074691
Inflammation, Joint swelling	Altered Intercellular Communication	Of all non-swollen joints (n=932), 232 joints (26%) had subclinical inflammation (>=1 MRI-inflammation feature present).	25074691
Inflammation	Altered Intercellular Communication	Radiographic progression was present in 4% of non-swollen joints with subclinical inflammation compared to 1% of non-swollen joints without subclinical inflammation (relative risks (RR) 3.5, 95% CI 1.3 to 9.6).	25074691
Inflammation	Altered Intercellular Communication	Radiographic progression was infrequent, but joints with subclinical inflammation had an increased risk of radiographic progression within year 1.	25074691
Inflammation	Altered Intercellular Communication	This demonstrates the relevance of MRI-detected subclinical inflammation.	25074691
Inflammation, Low muscle mass	Altered Intercellular Communication	Old age, comorbidities, protein-energy wasting, physical inactivity, low albumin, and inflammation associated with low muscle strength, but not with low muscle mass (multivariate ANOVA interactions).	25074839
Inflammation, Low muscle mass	Altered Intercellular Communication	Low muscle strength was more strongly associated with aging, protein-energy wasting, physical inactivity, inflammation, and mortality than low muscle mass.	25074839
Carcinogenesis, Neoplasms, prostatitis	Altered Intercellular Communication	There are accumulating epidemiological, experimental, and genetic data supporting that prostate inflammation may contribute to prostate carcinogenesis, and several inflammatory-related molecules have been linked to tumorigenesis and prognosis in several tumors.	25075566
Chronicity, Inflammation	Altered Intercellular Communication	A peritoneal biopsy showed morphological changes of acute inflammation and chronicity.	25076189
Inflammation, Pain Distress Question	Altered Intercellular Communication	Of the 30 patients, 25 have had no postoperative problems and five had mild inflammation, of which three patients developed intractable pain and underwent soft-tissue reduction.	25076228
Inflammation, Neoplasms, Diabetes Mellitus	Altered Intercellular Communication	Animal models have shown that hyperinsulinemic state underlying diabetes promotes tumor formation through stimulation of insulin-IGF-1 pathway; a possible role of inflammation is also proposed.	25076332
Inflammation, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Obesity and insulin resistance are hallmarks of the metabolic syndrome, which is associated with low-grade chronic inflammation.	25076422
Inflammation	Altered Intercellular Communication	Therefore, the circulating clusterin level may be a surrogate marker for obesity-associated systemic inflammation.	25076422
Glucose Metabolism Disorders, Inflammation, Cardiovascular Diseases, Communicable Diseases, Mood Disorders, Weight Gain, MS gene	Altered Intercellular Communication	Vitamin D deficiency has been known as a global health problem and there were reported moderate to strong inverse associations between 25(OH) D concentrations and cardiovascular diseases, serum lipid concentrations, inflammation, glucose metabolism disorders, weight gain, infectious diseases, multiple sclerosis, mood disorders, declining cognitive function, impaired physical functioning, and all-cause mortality.	25076695
Inflammation, Neoplasms, Colorectal Carcinoma, Ulcerative Colitis	Altered Intercellular Communication	It appears that tumor suppressor gene-VEGF axis have dual role on immune response in inflammation of UC and tumor growth and progression of CRC.	25076849
Inflammation, Hypothermia due to exposure, Necrosis	Altered Intercellular Communication	He developed muscarinic and nicotinic symptoms with hypothermia, inflammation in the site of the pesticide injection without necrosis.	25078103
Sacroiliitis, vascular inflammations, Arthritis, Psoriatic, Atherosclerosis	Altered Intercellular Communication	Psoriatic arthritis and sacroiliitis are associated with increased vascular inflammation by 18-fluorodeoxyglucose positron emission tomography computed tomography: baseline report from the Psoriasis Atherosclerosis and Cardiometabolic Disease Initiative.	25078679
Sacroiliitis, vascular inflammations, PROS1 gene	Altered Intercellular Communication	Because the presence of sacroiliitis may portend more severe PsA, we hypothesized that sacroiliitis defined by computed tomography (CT) would be associated with increased vascular inflammation defined by 18-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT), which is an established measure of CVD.	25078679
PROS1 gene, vascular inflammations, Sacroiliitis	Altered Intercellular Communication	Linear regression (with b-coefficients (b) and P-values reported for PsA and sacroiliitis) was used to adjust for CVD risk factors to determine associations of PsA or sacroiliitis with vascular inflammation.	25078679
Sacroiliitis, vascular inflammations	Altered Intercellular Communication	Vascular inflammation (measured as SUVmax) was greater (P < 0.001) in patients with sacroiliitis (mean +- SD = 7.33 +- 2.09) defined by CT compared to those without sacroiliitis (6.39 +- 1.49, P = 0.038).	25078679
PROS1 gene, Inflammation, Sacroiliitis	Altered Intercellular Communication	There were associations between PsA and aortic inflammation (b = 0.124, P < 0.001) and between sacroiliitis and aortic inflammation (b = 0.270, P < 0.001) after adjusting for CVD risk factors.	25078679
Sacroiliitis, vascular inflammations, Cyclophosphamide/Vincristine/Dacarbazine Regimen, PROS1 gene	Altered Intercellular Communication	Sacroiliitis predicted vascular inflammation beyond PsA and CVD risk factors (kh2 = 124.6, P < 0.001).	25078679
Sacroiliitis, vascular inflammations, Sacroiliac joint structure	Altered Intercellular Communication	Sacroiliitis is associated with increased vascular inflammation detected by FDG-PET/CT, suggesting that sacroiliac joint disease may identify patients at greater risk for CVD.	25078679
Inflammation	Altered Intercellular Communication	Upon histological examination, the degree of inflammation was subjectively graded as mild, moderate, or severe by 2 separate investigators.	25079201
Inflammation, Eczema of nipple, Data types - Address	Altered Intercellular Communication	Although nipple eczema may accompany AD, we found no definite differences in the degree or pattern of inflammation and cytokine expression level regardless of whether AD was present or not.	25079201
palladium, Gingivitis	Altered Intercellular Communication	In summary, this investigation supports salivary levels of IL-1ra and IL-6 as potential indicators for PD changes during induced gingival inflammation.	25079398
Inflammation, physiopathological	Altered Intercellular Communication	The detected transcriptional abnormalities also support robust inflammation, profound extracellular matrix impairments, broad metabolic dysfunction, aberrant oxidative stress, DNA damage, and cell death.	25079797
Inflammation	Altered Intercellular Communication	The data suggest that early treatment with prednisolone may modulate not only inflammation but also autoimmunity-associated pathogenetic mechanisms.	25079933
Inflammation, Colitis	Altered Intercellular Communication	Administration of the butyrate (a fermentation product of gut microbes) increases intestinal VDR expression and suppresses inflammation in a colitis model.	25080448
Inflammation, Anemia	Altered Intercellular Communication	EPO is a sensitive indicator of iron status across gestation, is not affected by systemic inflammation, and may better predict risk of anemia at term.	25080540
Inflammatory abnormality of the eye	Altered Intercellular Communication	Long-standing prosthetic eye wearing induces ocular surface inflammation.	25081289
Inflammation	Altered Intercellular Communication	Limited data exist on the presence and function of immune-competent cells in chronic tendinopathic tendons and their potential role in inflammation and tissue healing as well as in predicting long-term outcome.	25081311
Inflammation, Carcinogenesis, Nasopharyngeal carcinoma	Altered Intercellular Communication	Inflammation has been demonstrated to be widely involved in the carcinogenesis of nasopharyngeal carcinoma (NPC).	25081376
Inflammation, Coronary heart disease	Altered Intercellular Communication	Genetic and environmental influences on the prospective correlation between systemic inflammation and coronary heart disease death in male twins.	25082230
Cessation of life, Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Because of lack of evidence, we aimed to examine to what degree low-grade systemic inflammation and coronary heart disease (CHD) death shared common genetic and environmental substrates.	25082230
Inflammation	Altered Intercellular Communication	Low-grade systemic inflammation, measured by IL-6, and long-term CHD death share moderate genetic substrates that augment both traits.	25082230
Inflammation, Exudate	Altered Intercellular Communication	Specimens with conspicuous inflammation showed narrowed portions in the nasolacrimal duct, in which severe inflammation and exudate in the lumen was observed.	25082889
Inflammatory abnormality of the eye	Altered Intercellular Communication	Topical cyclosporine a 1% for the treatment of chronic ocular surface inflammation.	25083780
Inflammation, Periodontitis	Altered Intercellular Communication	The results of this study confirm the association between periodontal inflammation and increased cardiovascular risk shown by impaired vascular health in case of severe periodontitis.	25084111
Tumor necrosis, Inflammation	Altered Intercellular Communication	The decoy receptor 3 (DcR3) is a member of the tumour necrosis factor (TNF) receptor superfamily and may regulate inflammation.	25084482
Inflammation, Traumatic injury	Altered Intercellular Communication	Further, inflammation has been implicated in the long-term progression and severity of HI injury.	25084519
Communicable Diseases, Inflammation	Altered Intercellular Communication	Recently, inter-alpha inhibitor proteins (IAIPs) have been shown to attenuate inflammation in models of systemic infection.	25084519
Hyperlipidemia, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	Since hyperlipidemia, inflammation, insulin resistance and obesity increase breast cancer risk, elevating GH may serve to exacerbate cancer progression.	25085903
Inflammation	Altered Intercellular Communication	BMEP regions showed significantly increased bone density and structures as well as perfusion measures, suggesting bone remodeling and active inflammation.	25086074
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Visfatin correlates with inflammation and its levels in peripheral blood are associated with some inflammatory diseases.	25086268
Inflammation, Acute Cholecystitis	Altered Intercellular Communication	Thus, high plasma levels of visfatin are associated with systemic inflammation, and may independently predict conversion of laparoscopic cholecystectomy to open surgery in acute cholecystitis.	25086268
Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Hypothalamic structure	Altered Intercellular Communication	These results reveal an atypical, mRNA metabolism-driven hypothalamic nuclear factor-kB activation, a mechanism that links obesity as well as aging to hypothalamic inflammation and ultimately to type 2 diabetes.	25086906
Neuromyelitis Optica, Extrapontine Myelinolysis, Inappropriate ADH Syndrome	Altered Intercellular Communication	[Case of neuromyelitis optica spectrum disorder associated with central pontine and extrapontine myelinolysis preceded by syndrome of inappropriate antidiuretic hormone secretion].	25087556
Chronic lymphocytic inflammation, Pontine structure, Swelling, Clippers	Altered Intercellular Communication	[Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) associated with swelling in the brainstem: a case report].	25087561
Chronic lymphocytic inflammation, Pontine structure, Clippers	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a rare central nervous system inflammatory disease characterized by the punctate gadolinium enhancement peppering the pons and the cerebellar peduncles as neuroimaging.	25087561
Inflammation	Altered Intercellular Communication	Dietary and endogenous fatty acids could play a role in low-grade inflammation.	25087591
Inflammation, Dysplasia, Abnormal Epithelial Cell	Altered Intercellular Communication	Biopsies are classified as indefinite for dysplasia (IND) when the significance of epithelial abnormalities is uncertain due to inflammation or sampling.	25087917
Cerebral Infarction	Altered Intercellular Communication	In light of the increased risk of further progression of cerebral infarction, we decided to perform surgical revascularization in spite of her active inflammatory condition.	25088171
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation is one possible mechanism underlying the associations between mental disorders and cardiovascular diseases (CVD).	25088287
SYN2 gene	Altered Intercellular Communication	Synapsin II (SynII), a neuron specific phosphoprotein plays a major role in synaptogenesis and neurotransmitter release.	25088614
Inflammation, Asthma	Altered Intercellular Communication	Vitamin D is hypothesized to have some roles in innate and adaptive immunity, inflammation reduction, and remodeling; therefore, it is supposed to affect the asthma phenotype, severity, and response to inhaled corticosteroid (ICS).	25091714
Inflammation	Altered Intercellular Communication	Thus, glycans may potentially be triggering or perpetuating inflammation.	25092526
Cardiac Arrest, Inflammation	Altered Intercellular Communication	The kynurenine pathway (KP) is the major route of tryptophan (TRP) catabolism and is activated by inflammation and after cardiac arrest in animals.	25092787
Impaired cognition	Altered Intercellular Communication	The data suggest that ammonia toxicity and HE are associated with premature astrocyte senescence, which may impair neurotransmission and contribute to persistence of cognitive disturbances after resolution of episodes of overt HE.	25092802
Decreased glomerular filtration rate, Inflammation, Anemia	Altered Intercellular Communication	The pathogenesis of anemia was multifactorial, with decreased renal function (glomerular filtration rate <60 mL/min/1.73 m(2)), signs of inflammation, and functional iron deficiency detected in 11.4% of anemic patients.	25092968
Renal Insufficiency, Inflammation	Altered Intercellular Communication	A complex and heterogeneous interplay of chronic inflammation, functional iron deficiency, and renal impairment was identified in a large proportion of patients.	25092968
Inflammation, Anxiety, CTCAE 3.0, Depression, CTCAE, Sleep disturbances	Altered Intercellular Communication	Cross-sectional associations of complaints of sleep disturbances with cardiovascular risk factors and disease, biomarkers of inflammation, depression, anxiety, and physical health status were analyzed.	25093413
Inflammation, FAM126A gene	Altered Intercellular Communication	These data suggest that inflammation via the NFkB pathway play an important role in modulating gene expression of HCC patients through methylation.	25093504
Inflammation, Ulcer	Altered Intercellular Communication	Detected somewhat smaller difference in the degree of risk in the treatment of existing and improved schemes ulcer and neasotsiyovanoyi it when the underlying disease complicated by chronic inflammation, in our opinion, due to greater perfection, adapted first for this category of patients, among other options.	25095689
Vascular Diseases, Interstitial inflammation, Fibrosis Assessment, Tubulitis Assessment, Arteriolar Hyaline Thickening Assessment	Altered Intercellular Communication	The mean scores of interstitial inflammation (interstitial inflammation and tubulitis), scarring (interstitial fibrosis/tubular atrophy), and vascular disorders (arteriolar hyaline thickening and vascular intimal fibrosis) were significantly higher in late than early acute cellular rejection.	25095709
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation has a prominent role in the development of atherosclerosis.	25095741
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	Type 2 diabetes could contribute to atherosclerosis development by promoting inflammation.	25095741
Intermittent Claudication, Peripheral Arterial Diseases, Musculoskeletal Physiological Phenomena	Altered Intercellular Communication	Inflammation contributes to the development of peripheral artery disease (PAD) and may contribute to intermittent claudication by adversely affecting vascular and skeletal muscle function.	25095746
Inflammation, Impaired health, Intermittent Claudication	Altered Intercellular Communication	Systemic inflammation, as indicated by TNF-a inflammatory gene expression in peripheral blood monocytes and by circulating biomarker levels, is associated with impairment in walking time in patients with PAD and intermittent claudication.	25095746
Inflammation, Thrombosis	Altered Intercellular Communication	Galectin-3, a biomarker linking oxidative stress and inflammation with the clinical outcomes of patients with atherothrombosis.	25095870
Inflammation, Thrombosis	Altered Intercellular Communication	Galectin-3 (Gal-3) participates in different mechanisms involved in atherothrombosis, such as inflammation, proliferation, or macrophage chemotaxis.	25095870
Rupture, Inflammation, Atherosclerosis	Altered Intercellular Communication	Gal-3 extracellular levels could reflect key underlying mechanisms involved in atherosclerosis etiology, development, and plaque rupture, such as inflammation, infiltration of circulating cells and oxidative stress.	25095870
ARCN1 gene, Specific antibody deficiency, Inflammation	Altered Intercellular Communication	We hypothesised that functional defects in Tregs may promote increased inflammation contributing to the pathogenesis of COPD.	25097153
ARCN1 gene, Inflammation, Obesity	Altered Intercellular Communication	Obesity and/or perturbed homeostasis of Treg subsets may explain this defect and therefore contribute to increased inflammation observed in COPD.	25097153
Inflammation, Keratitis	Altered Intercellular Communication	Acanthamoeba keratitis was defined as the presence of AK with concurrent ipsilateral scleral inflammation.	25097155
Inflammation, Pain Distress Question	Altered Intercellular Communication	Control of scleral inflammation and pain was achieved in all but 2 eyes (2 enucleations).	25097155
methyldopa, Inflammation, Hypertension, CTCAE, Communicable Diseases	Altered Intercellular Communication	The new evidence strongly suggests a relationship between AMD development and hypertension (p < 0.001; r = +0.30, P < 95%) as well as between AMD progression and hypertension accompanied by chronic inflammation with predominantly intracellular localization of the infectious agent (p < 0.05 for the predisciform stage, p < 0.001 for the disciform and cicatrical stages; r = +0.30, P < 95%).	25098114
methyldopa, Inflammation, Hypertension, CTCAE, Communicable Diseases	Altered Intercellular Communication	AMD progression is associated with hypertension accompanied by chronic inflammation with predominantly intracellular localization of the infectious agent as well as impairment of the interferon response (systemic decrease of IFNalpha and IFNgamma with local increase of IFNalpha).	25098114
Inflammation, Presenile dementia, Chronic osteomyelitis, cyclophosphamide/methotrexate/vincristine protocol, Disease	Altered Intercellular Communication	The role of chronic osteomyelitis (COM), a disorder characterized by persistent inflammation, in dementia development has not been fully explored.	25098680
Inflammation, Myositis, CTCAE 5.0	Altered Intercellular Communication	Upregulation of immunoproteasome subunits in myositis indicates active inflammation with involvement of antigen presenting cells, CD8 T-cells and IFNG.	25098831
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome criteria as predictors of insulin resistance, inflammation and mortality in chronic hemodialysis patients.	25099153
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Diagnosis of metabolic syndrome by HMetS was simultaneously capable of revealing both inflammation and IR, whereas NCEP ATP III and IDF criteria were only able to identify IR.	25099153
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	IR and inflammation predict metabolic syndrome only when diagnosed by HMetS criteria.	25099153
Inflammation, Necrosis, Blood Clot, Bulla, Vasculitis, CTCAE	Altered Intercellular Communication	Premortem and autopsy skin biopsies demonstrated epidermal necrosis, subepidermal bullae, and fibrin thrombi within small cutaneous vessels with minimal perivascular lymphocytic inflammation and without accompanying vasculitis.	25099358
Gastrointestinal inflammation, Colitis	Altered Intercellular Communication	In CD colitis mice, intestinal inflammation via CD4(+) T cell hyperactivation was induced by food antigens associated with high serum IgG levels and was ameliorated by the elimination of food antigens.	25099432
Hyponatremia	Altered Intercellular Communication	Patients with new-onset severe hyponatremia and no obvious pharmacologic or systemic cause should undergo pituitary hormonal evaluation and brain imaging.	25100360
Tyrosine Transaminase Deficiency Disease, hyponatremic	Altered Intercellular Communication	Surgical resection and correction of hormonal deficiencies are associated with resolution of recurrent hyponatremic episodes.	25100360
Alzheimers Disease	Altered Intercellular Communication	Is Alzheimer's Disease Autoimmune Inflammation of the Brain That Can be Treated With Nasal Nonsteroidal Anti-Inflammatory Drugs?	25100747
Alzheimers Disease", Have Autoimmune or Inflammatory Condition, MS gene	Altered Intercellular Communication	Like Alzheimer's, multiple sclerosis, an autoimmune inflammation of the central nervous system, has a female to male ratio of 2.3.	25100747
Inflammation, Diverticulum	Altered Intercellular Communication	Laboratory parameters revealed inflammation signs, and instrumental examinations showed the presence of diverticula in the ascending colon.	25100894
Inflammation, Atherosclerosis	Altered Intercellular Communication	Chronic inflammation and immunosenescence result in early onset of conditions associated with aging, including atherosclerosis and frailty.	25101530
Inflammation	Altered Intercellular Communication	These changes correlate with inflammation and disease duration and suggest that disconnection of oligodendrocytes from reactive astrocytes may play a role in failed remyelination and disease progression.	25101702
Inflammation, Intracranial Aneurysm, Rupture	Altered Intercellular Communication	Chronic inflammation contributes to remodeling, degeneration, and rupture of saccular intracranial artery aneurysms.	25101705
Inflammation, Oral infection, Periodontitis, Endothelium	Altered Intercellular Communication	These findings further support the notion that oral infections have extraoral effects and document that periodontitis is associated with a mobilization of EPCs from the bone marrow, apparently in response to systemic inflammation and endothelial injury.	25101916
Inflammation, Obesity	Altered Intercellular Communication	In non-diabetic subjects, a mechanism has been proposed in which chronic inflammation associated with obesity increases albumin metabolism and negatively regulates GA levels.	25102071
Inflammation	Altered Intercellular Communication	BMI was significantly positively correlated with CRP, but CRP was not significantly correlated with GA. HOMA-b was significantly positively correlated with BMI and significantly negatively correlated with GA. Multivariate analysis showed that HOMA-b was a significant explanatory variable for GA, but not CRP and HOMA-R. Our findings suggest that insulin secretion plays a greater role than chronic inflammation in the mechanism by which BMI negatively regulates GA in T2DM patients.	25102071
Inflammation, Chronic disease	Altered Intercellular Communication	Inflammation is implicated in the development of chronic diseases and increases the risk of mortality.	25102453
Inflammation	Altered Intercellular Communication	Daily positive events may serve a protective role against inflammation.	25102453
Ulcerative Colitis, Colitis	Altered Intercellular Communication	Whole Fusobacterium species, but not F. nucleatum, are common in UC patients and have a role in persistence of colonic inflammation in UC.	25102986
Airway structure, ARCN1 gene	Altered Intercellular Communication	Association between pathogens detected using quantitative polymerase chain reaction with airway inflammation in COPD at stable state and exacerbations.	25103335
Airway structure, ARCN1 gene	Altered Intercellular Communication	Relationships between airway inflammation and respiratory potentially pathogenic microorganisms (PPMs) quantified using quantitative polymerase chain reaction (qPCR) in subjects with COPD are unclear.	25103335
Airway structure, ARCN1 gene	Altered Intercellular Communication	Our aim was to evaluate mediators of airway inflammation and their association with PPMs in subjects with COPD at stable state and during exacerbations.	25103335
Airway structure, ARCN1 gene	Altered Intercellular Communication	At stable state, H influenzae is associated with increased airway inflammation in COPD.	25103335
Airway structure	Altered Intercellular Communication	The relationship between bacterial load changes of specific pathogens and airway inflammation at exacerbation and recovery warrants further investigation.	25103335
TG gene, Inflammation	Altered Intercellular Communication	Patients with isolated TG were older (52 +- 14 vs. 35 +- 14; p = 0.0048), received grafts from older donors (54 +- 16 vs. 41 +- 18; p = 0.0554), and displayed a lower inflammation in the glomerular (g-score: 0.5 +- 0.5 vs. 1.0 +- 0.9; p = 0.0865; CD3 positive cells/glomeruli: 1.5 +- 2.9 vs. 4.4 +- 4.1; p = 0.0147), interstitial (i-score: 1.2 +- 0.9 vs. 1.9 +- 1.0; p = 0.0685; CD45 positive cells/hpf: 18 +- 11 vs. 57 +- 68; p = 0.0132), and peritubular capillary (ptc-score 0.2 +- 0.6 vs. 1.1 +- 0.9; p = 0.0089; CD45 positive cells/hpf: 3.7 +- 3.1 vs. 10.1 +- 7.4; p = 0.0290) compartments.	25103874
TG gene, Inflammation	Altered Intercellular Communication	Isolated TG is associated with less severe allograft inflammation and with a better outcome than chronic AMR.	25103874
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) defines a group of disorders characterized by persistent inflammation of the sinonasal tract.	25104359
Inflammation	Altered Intercellular Communication	Features of epithelial dedifferentiation towards a mesenchymal phenotype are observed in CRSwNP and CRSsNP and correlate with airway fibrosis and inflammation.	25104359
Myelitis, Tropical Spastic Paraparesis	Altered Intercellular Communication	Human T-lymphotropic virus type 1 (HTLV-1) can cause chronic spinal cord inflammation, known as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).	25104771
TNF protein, human, Inflammation, Hypertension, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	The present studies have demonstrated an independent association of higher PP with higher TNF-a, a marker of insulin resistance, and neutrophil count in community-living elderly women and suggest that insulin resistance and chronic low-grade inflammation may in part be responsible for the association between high PP and incident type 2 diabetes found in elderly patients with hypertension.	25105150
Acute heart failure	Altered Intercellular Communication	The systemic inflammation-based Glasgow Prognostic Score as a prognostic factor in patients with acute heart failure.	25105282
Inflammation	Altered Intercellular Communication	The GPS, which is based on systemic inflammation, is useful for predicting the prognoses of hospitalized patients with ADHF.	25105282
Inflammation	Altered Intercellular Communication	The objective of this study was to compare epidemiology, causative pathogens, outcome, and levels of laboratory markers of inflammation of community-onset (i.e.	25105287
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is increasingly being recognized as an important factor in the pathogenesis of atherosclerosis and outcome of percutaneous coronary intervention (PCI).	25105946
Inflammatory Bowel Diseases	Altered Intercellular Communication	The impact of hormonal contraception on disease-related cyclical symptoms in women with inflammatory bowel diseases.	25105949
Barrett Esophagus, Inflammation, Adenocarcinoma Of Esophagus	Altered Intercellular Communication	Inflammation and oxidative stress markers and esophageal adenocarcinoma incidence in a Barrett's esophagus cohort.	25106775
Inflammation, Adenocarcinoma Of Esophagus, Malignant Neoplasms	Altered Intercellular Communication	Prediagnostic inflammation markers predict several cancers, but their role in predicting esophageal adenocarcinoma is unknown.	25106775
Barrett Esophagus, Inflammation, Adenocarcinoma Of Esophagus	Altered Intercellular Communication	Further research is needed to evaluate the role of inflammation and associated markers in esophageal adenocarcinoma development in persons with Barrett's esophagus.	25106775
Inflammation, Adenocarcinoma Of Esophagus	Altered Intercellular Communication	This prospective study suggests that inflammation markers, particularly CRP and IL6, may help identify persons at higher risk of progression to esophageal adenocarcinoma.	25106775
Cardiovascular morbidity, Hypopituitarism	Altered Intercellular Communication	Chronic hypopituitarism, particularly growth hormone (GH) deficiency is related to the increased cardiovascular morbidity and mortality.	25107344
Inflammation	Altered Intercellular Communication	This difference may ensource from deterioration of the balance of these substances due to oxidative stress and inflammation.	25107374
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Association between serum uric acid and inflammation in rheumatoid arthritis: perspective on lowering serum uric acid of leflunomide.	25108207
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The association between serum uric acid concentrations and inflammation in patients with rheumatoid arthritis (RA) has been still controversial.	25108207
Refractory anemias, Inflammation	Altered Intercellular Communication	This implies that uric acid may not influence systemic inflammation in RA.	25108207
Inflammation, Nephritis	Altered Intercellular Communication	We then divided this population again into group 3 (n = 20) with <= 25% inflammation and group 4 (n = 18) with >26% inflammation based on the Banff score for renal parenchyma inflammation.	25109692
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The accuracy of ZC in determining moderate cortical fibrosis and moderate inflammation was examined by receiver operating characteristic analysis.	25109692
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The area under the receiver operating characteristic curve was 0.992 +- 0.010 for fibrosis and 0.988 +- 0.021 for inflammation.	25109692
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	ZC is a new strain marker that could be straightforward to interpret and perform, making it a potentially practical approach for monitoring progression of cortical fibrosis or inflammation in renal allografts.	25109692
Crohn Disease	Altered Intercellular Communication	Crohn's disease (CD) is a lifelong, relapsing and remitting inflammatory condition of the intestine.	25110044
Inflammation, Diverticulitis	Altered Intercellular Communication	Furthermore, left-sided disease was significantly associated with a higher incidence of complicated diverticulitis (89.2% vs 57.5%, P < 0.01), combined resection due to extensive inflammation (21.6% vs 5.0%, P < 0.05), operative complications (51.4% vs 27.5%, P < 0.05), and in-hospital mortality (10.8% vs 0%, P < 0.05), along with longer post-operative hospitalization duration (21.3 +- 10.2 d vs 10.6 +- 8.1 d, P < 0.05).	25110438
Inflammation	Altered Intercellular Communication	Modeling the association between lifecourse socioeconomic disadvantage and systemic inflammation in healthy adults: The role of self-control.	25110854
Inflammation	Altered Intercellular Communication	Results showed that lower self-control primarily operated through higher abdominal adiposity to associate with greater inflammation.	25110854
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Gender, diabetes, glomerular filtration rate (GFR), hemoglobin, PTH, markers of mineral metabolism, inflammation, iron status and nutrition were variables of adjustment in univariate and multivariate analysis.	25113067
Hyperparathyroidism, Anemia	Altered Intercellular Communication	Parathyroid hormone (PTH) has been associated with anemia only in dialysis patients with severe hyperparathyroidism.	25113067
Leishmaniasis, Visceral, Renal tubular disorder, Nephritis	Altered Intercellular Communication	Preliminary study on tubuloglomerular dysfunction and evidence of renal inflammation in patients with visceral leishmaniasis.	25114011
Nephritis	Altered Intercellular Communication	Urinary MCP-1 and MDA are elevated in patients with VL, which suggests renal inflammation and incipient renal damage.	25114011
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The role of interleukins in the severity and clinical profile of chronic obstructive pulmonary disease (COPD) is not known, but evidence supports the contribution of systemic inflammation to disease pathophysiology.	25114519
Fitz-Hugh-Curtis syndrome, Inflammation, Pelvic Inflammatory Disease	Altered Intercellular Communication	Fitz-Hugh-Curtis syndrome (FHCS) is caused by inflammation of perihepatic capsules associated with pelvic inflammatory disease.	25115526
Inflammation	Altered Intercellular Communication	NTM infection can cause various clinical manifestations, which in the present case, overlapped with the symptoms of perihepatic inflammation seen in FHCS.	25115526
Inflammation, Bothered by Vomiting, Diarrhea, Asthenia, Fatigue	Altered Intercellular Communication	A total of 85.8 % of all patients experienced at least one AE: fatigue (56.7 %), vomiting (40.1 %), diarrhea (33.7 %), asthenia (32.8 %), and mucosal inflammation (20.8 %).	25115744
Inflammation	Altered Intercellular Communication	On multivariate logistic regression analysis, oxidative stress index (b = 0.868, 95% confidence interval [CI] = 0.806-0.934, P < .001), neutrophil to lymphocyte ratio, uric acid, mean platelet volume, Killip 2 to 4 class, and initial SYNTAX score were independently associated with SR. Oxidative stress as well as inflammation may play a pivotal role in the pathogenesis of SR in patients with STEMI.	25115763
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	Growth differentiation factor 15 (GDF-15), a member of the transforming growth factor superfamily, is produced by cardiomyocytes and atherosclerotic lesions under stress conditions such as inflammation.	25117302
Malnutrition, HD Term Type, Inflammation, Atherosclerosis	Altered Intercellular Communication	The relationship between serum GDF-15, mortality, and carotid artery thickening suggests that GDF-15 may be a novel marker of atherosclerosis, inflammation, and malnutrition in HD patients.	25117302
Inflammation, Fibrosis Assessment, Calcified (qualifier)	Altered Intercellular Communication	Histologically, they contained variable amounts of hyaline ribbons and rings, inflammation, foreign body giant cells, calcifications, and food; larger lesions displayed circumferential stellate fibrosis (12/22).	25118813
Cataract, Inflammation	Altered Intercellular Communication	Surgical inflammation associated with cataract surgery caused a significant increase of macular thickness in control and DR eyes that were not treated with intravitreous bevacizumab.	25118827
Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	Cardiac surgery is accompanied by an increase of oxidative stress, a significantly reduced antioxidant (AOX) capacity, postoperative inflammation, all of which may promote the development of organ dysfunction and an increase in mortality.	25118980
Inflammation, Hematuria, CTCAE	Altered Intercellular Communication	Laboratory tests revealed evidence of an inflammation and a hematuria.	25119306
Neurodegenerative Disorders, Inflammation, Nerve Degeneration, Mitochondria, Neuronal loss in central nervous system	Altered Intercellular Communication	Despite exhibiting different clinical profiles and selective neuronal loss, common features such as abnormal protein deposition, dysfunctional cellular transport, mitochondrial deficits, glutamate excitotoxicity, iron accumulation and inflammation are observed in many neurodegenerative disorders, suggesting converging pathways of neurodegeneration.	25119539
Multiple Organ Failure, Inflammation, Lung Injury, Hypoxemia	Altered Intercellular Communication	It causes inflammation of the lung parenchyma leading to impaired gas exchange with a systemic release of inflammatory mediators, causing consequential lung tissue injury, hypoxemia and frequently multiple organ failure.	25120850
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	A therapeutic regimen reducing FABP4 expression within the atherosclerotic plaque may promote lesion stability through modulation of endoplasmic reticulum stress signaling, and attenuation of apoptosis, lipid burden, and inflammation.	25122052
Inflammation	Altered Intercellular Communication	Nevertheless, in some reports, electrode extrusion, chronic inflammation, and even soft failure of the implant system have been attributed to a tissue response to the electrode.	25122600
Inflammation, Impaired cognition	Altered Intercellular Communication	Long-term systemic inflammation and cognitive impairment in a population-based cohort.	25123210
Inflammation, Impaired cognition	Altered Intercellular Communication	Evidence suggests inflammation is associated with cognitive impairment, but previous epidemiological studies have reported conflicting results.	25123210
Inflammation, Impaired cognition	Altered Intercellular Communication	Further studies of long-term inflammation and cognitive impairment are needed.	25123210
Inflammation, Asthma	Altered Intercellular Communication	The small airways are an important site of inflammation in asthma.	25123492
Refractory anemias, Inflammation	Altered Intercellular Communication	We studied the usefulness of magnetic resonance imaging (MRI) in detecting subclinical inflammation in patients with asymptomatic RA and tested the hypothesis of interleukin (IL)-18 as a marker of disease activity.	25123522
Refractory anemias, Superficial ulcer, Inflammation	Altered Intercellular Communication	MRI is more sensitive in detecting erosions compared with X-rays, and is superior in its ability to detect subclinical inflammation in RA patients.	25123522
Inflammation, Bodily secretions	Altered Intercellular Communication	Induced sputum allows to measure mediators of asthmatic inflammation in bronchial secretions.	25123806
Intraocular inflammation, Humor, Atrophic iris	Altered Intercellular Communication	Among the three groups of patients, the characteristic features of those with VZV-AU were severe intraocular inflammation, as shown by severe aqueous flare, highest viral load in the aqueous humor, and presence of segmental iris atrophy.	25124341
Intraocular inflammation	Altered Intercellular Communication	In comparison, patients with CMV-AU had the mildest intraocular inflammation, lowest corneal endothelial cell density, and highest IOP.	25124341
Delirium, Inflammation	Altered Intercellular Communication	This study provides novel evidence of CNS inflammation involving the IL-1b family in delirium and suggests a rise in CSF IL-1b early in delirium pathogenesis.	25124807
Delirium, Inflammation	Altered Intercellular Communication	Future larger CSF studies should examine the role of CNS inflammation in delirium and its sequelae.	25124807
Inflammation, Endothelial dysfunction, Coronary Lesions Treated	Altered Intercellular Communication	Ongoing low-grade inflammation and endothelial dysfunction persist in children with coronary lesions diagnosed with Kawasaki disease (KD).	25124974
Coronary Aneurysm, Inflammation	Altered Intercellular Communication	Pravastatin improves endothelial function and reduces low-grade chronic inflammation in patients with coronary aneurysms due to KD.	25124974
Inflammatory abnormality of the eye	Altered Intercellular Communication	In this observational small case series, data were collected successively from May 1, 2012, through February 31, 2013, from patients with clinical signs of ocular inflammation treated with vemurafenib at the Department of Ophthalmology, Cochin-Hotel-Dieu Hospital.	25125216
Inflammation, Panuveitis, Retinal Detachment, Uveitis, Manufactured sign	Altered Intercellular Communication	The mean (SD) time until the appearance of ocular signs was 5.6 (2.3) months (range, 19 days to 7 months), and inflammation ranged from mild or low-grade anterior uveitis to severe explosive panuveitis complicated by retinal detachment.	25125216
Inflammation, Primary malignant neoplasm, Chronic Obstructive Airway Disease, Chronic disease, Muscle (organ)	Altered Intercellular Communication	This is important because a number of age-related clinical circumstances trigger acute and chronic muscle loss including cancer, chronic obstructive pulmonary disease, hospitalization, acute and chronic illness, and diseases in which systemic inflammation occurs.	25125716
Airway structure, Inflammation	Altered Intercellular Communication	It results from chronic inflammation and causes irreversible airway damage.	25125975
ARCN1 gene, Inflammation	Altered Intercellular Communication	Levels of different serum cytokines could be surrogate biomarkers for inflammation and lung function in COPD.	25125975
Inflammation, Periodontitis, Demographics Domain	Altered Intercellular Communication	Periodontitis in these patients is characterized by severe inflammation and tissue breakdown, and its diagnosis is important for cures of periodontitis and DM.	25126693
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Accumulation of b-amyloid (Ab) and resultant inflammation are critical pathological features of Alzheimer disease (AD).	25126727
Burn Specimen Source Codes	Altered Intercellular Communication	Ascorbic acid (vitamin C) decreases systemic inflammation and lowers fluid requirements after thermal injury; therefore it has been adopted in many burn centers as an adjunct to resuscitation.	25127026
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Potential utility of a new ulcerative colitis segmental endoscopic index combining disease severity and the extent of inflammation.	25127112
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	To investigate the potential utility of a new scoring system, the Ulcerative Colitis Segmental Endoscopic Index (UCSEI), which combines measures of disease severity and extent of inflammation.	25127112
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	UCSEI, reflecting disease severity and extent of inflammation, provides useful information for UC management that is not available with MES.	25127112
Intraocular inflammation, Unspecified visual loss	Altered Intercellular Communication	In the perioperative period following the second of the two surgeries, both patients developed severe, bilateral intraocular inflammation and profound vision loss.	25127533
Appendicitis, CTCAE	Altered Intercellular Communication	The proposed CT criterion of the DWC is not affected by normal distension or periappendiceal inflammation but only by true appendicitis.	25127845
Inflammation, Depression, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	Further investigation into this relationship could aid in understanding the mechanisms underlying inflammation, depression, and diabetes.	25128285
Hepatitis A, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver biopsy samples were classified into five levels of inflammation (G) and fibrosis (S) stages, according to the Chinese guidelines for prevention and treatment of viral hepatitis.	25128299
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Two multivariable ordinal regression models were performed to determine associations between AFP, GGT, and APRI (AST/PLT ratio) and stages of inflammation and fibrosis.	25128299
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Significant positive and moderate correlations were shown between AFP levels and inflammation stages and between AFP levels and fibrosis stages (r = 0.436 and 0.404, p < 0.001).	25128299
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Receiver operating characteristic (ROC) curve analyses revealed that the areas under the curves (AUCs) were 0.685, 0.727, and 0.755 (all p <0.001) for judging inflammation stages of G >= 2, G >= 3, G = 4 by AFP; and 0.691, 0.717, and 0.718 (all p <0.001) for judging fibrosis stages of S >= 2, S >= 3, and S = 4 by AFP.	25128299
Inflammation, Fibrosis Assessment, Complete atrioventricular block	Altered Intercellular Communication	Serum AFP levels increased as pathological levels of inflammation and fibrosis increased in CHB patients.	25128299
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Our data showed the clinical significance of serum AFP levels in diagnosing liver inflammation and fibrosis.	25128299
Inflammation, Paresis, Paralysed	Altered Intercellular Communication	This leads to nerve inflammation and damage that can cause muscle weakness and/or paralysis, including foot drop.	25128306
Inflammation, Autoimmune Diseases, Exocrine Glands, "Sjogrens Syndrome", PEELING SKIN SYNDROME	Altered Intercellular Communication	Characterized by chronic inflammation, dysfunction of exocrine glands, and systemic autoimmunity, primary Sjogren syndrome (pSS) is a common autoimmune disease in elderly women.	25128511
Sepsis, Communicable Diseases, Inflammation	Altered Intercellular Communication	Differentiating sepsis from other noninfectious causes of systemic inflammation is often difficult in the elderly.	25130150
Inflammation, Acute depression, Bipolar Disorder	Altered Intercellular Communication	Persistent inflammation and its relationship to leptin and insulin in phases of bipolar disorder from acute depression to full remission.	25130211
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Patients with bipolar disorder in depressive episodes may exhibit persistent inflammation with elevated levels of hs-CRP, IL-1Ra, sTNF-R1, and sIL-2R but not sIL-6R from the acute phases to full remission.	25130211
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Rejection episodes and graft failure were recorded, together with preoperative risk factors (glaucoma, neovascularization and active inflammation).	25130326
Inflammation, Overweight, Cardiovascular Diseases	Altered Intercellular Communication	Research investigating dietary influences on inflammation has focused primarily on the relationship between dietary characteristics, CRP elevation and BMI in the populations at greatest risk for cardiovascular disease, namely those in the overweight and obese ranges, often in clinical settings and/or among those middle aged or older, leaving little information about normal to underweight populations of reproductive age in ecological settings.	25130535
Xanthogranulomatous inflammation, Blood Clot, Necrosis	Altered Intercellular Communication	Histology of the resected unhealthy graft showed an arterial thrombus with xanthogranulomatous inflammation and necrosis.	25131097
Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Endothelial dysfunction, Hypertension, CTCAE	Altered Intercellular Communication	High serum uric acid (SUA) levels are present in patients with metabolic syndrome (MetS), when the latter is associated with endothelial dysfunction, inflammation, and hypertension.	25131560
Inflammation	Altered Intercellular Communication	In order to avoid further displacement due to the inflammation, 61 was extracted at the first appointment.	25131644
Inflammation, Electrocardiogram: myocardial infarction (finding), Rupture	Altered Intercellular Communication	Acute myocardial infarction (AMI), is related to a diffuse active inflammation of the coronary tree associated with rupture of one of the multiple vulnerable plaques.	25131923
Inflammation, Dental Plaque	Altered Intercellular Communication	The presence of soluble mediators of inflammation with their synergic or antagonistic actions coordinates the physiological response determining the plaque fate and the fatal event.	25131923
Acute myocardial infarction, Inflammation	Altered Intercellular Communication	The presence of CX3CR1 polymorphisms is significantly correlated with the incidence and the outcome of acute myocardial infarction inducing in the whole coronary tree a strong recruitment of Th1 polarized inflammation that is directly correlated to PTX3 expression.	25131923
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	YKL-40 as a novel factor associated with inflammation and catabolic mechanisms in osteoarthritic joints.	25132728
Inflammation, Asthma, Rheumatoid Arthritis, Tissue injury	Altered Intercellular Communication	YKL-40 is associated with tissue injury and inflammation, and consequently to diseases in which these mechanisms lead to tissue degradation, for example, asthma and rheumatoid arthritis.	25132728
Cartilage destruction, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	The present study introduces YKL-40 as a cartilage-derived factor associated with mediators of inflammation and cartilage destruction involved in the pathogenesis of OA.	25132728
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	CAP was not correlated with inflammation degree and fibrosis degree (r = -0.025, P > 0.05; r = 0.	25132779
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Relationship between methylation and colonic inflammation in inflammatory bowel disease.	25132780
Inflammatory Bowel Diseases, Colitis	Altered Intercellular Communication	To investigate the relationship between the methylation status in the SLIT2 and TGFB2 promoters and colonic inflammation in inflammatory bowel disease patients.	25132780
Inflammation	Altered Intercellular Communication	SLIT2 methylation was also higher in samples with acute inflammation (56.5%) than in samples with chronic (24%) or absent inflammation (15%) (P < 0.001).	25132780
Inflammation	Altered Intercellular Communication	In the multivariate analysis, only inflammation status (and not disease duration or extension) was independently associated with SLIT2 methylation [OR = 6.6 (95%CI: 1.65-27.36), P = 0.009].	25132780
Inflammation	Altered Intercellular Communication	Endoscopic and histological inflammation are predictive for SLIT2 methylation.	25132780
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	We are often confronted with patients in the "gray zone" (prostate-specific antigen [PSA]<10 ng/mL) whose biopsies reveal no malignancy but only inflammation.	25132947
Inflammation, Prostate carcinoma	Altered Intercellular Communication	We investigated the relationship between histological inflammation and total PSA (tPSA), free PSA (fPSA), and percentage of free PSA (f/tPSA) levels in patients without prostate cancer (PC).	25132947
Inflammation, prostatitis	Altered Intercellular Communication	Subclinical inflammation has a significant influence on fPSA in patients with tPSA<10 ng/mL but without PC or clinical prostatitis.	25132947
Inflammation	Altered Intercellular Communication	Subclinical inflammation is not characterized by elevated tPSA alone but also by a decreased fPSA, a tendency similar to that in PC.	25132947
Coinfection, Inflammation	Altered Intercellular Communication	Coinfection with human herpesvirus 8 is associated with persistent inflammation and immune activation in virologically suppressed HIV-infected patients.	25133669
Communicable Diseases, Inflammation	Altered Intercellular Communication	Infection with co-pathogens is one of the postulated factors contributing to persistent inflammation and non-AIDS events in virologically-suppressed HIV-infected patients.	25133669
Coinfection, Inflammation, human herpesvirus 8	Altered Intercellular Communication	In virologically suppressed HIV-infected patients, coinfection with HHV-8 is associated with increased inflammation and immune activation.	25133669
Anxiety, CTCAE 3.0, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Patients experiencing depression or anxiety and those with elevated inflammation may be at particular risk for poor sleep.	25133898
Communicable Diseases, Noncommunicable Diseases, Inflammation	Altered Intercellular Communication	Serum procalcitonin is commonly used to differentiate systemic inflammation due to infection from non-infectious causes.	25134378
Acute inflammation	Altered Intercellular Communication	Patients at low risk for postoperative inflammation were recruited and randomized to the nepafenac group or to the control group.	25135542
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histopathology of the grafts of eyes that required repeat DSAEK showed no inflammation, no foreign-body deposit, and no fibrosis.	25135544
Autosomal Recessive Disorder, Inflammation	Altered Intercellular Communication	Leukocyte adhesion deficiency type 1 (LAD-1) is an autosomal recessive disorder, caused by the absence or reduced expression of the beta-2 integrins on granulocytes, and characterized by the inability of these cells to emigrate from the bloodstream towards the sites of tissue inflammation.	25135596
ARCN1 gene, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Persistent systemic inflammation and symptoms of depression among patients with COPD in the ECLIPSE cohort.	25135745
ARCN1 gene, Inflammation, Depression, CTCAE	Altered Intercellular Communication	The relationship of depression with systemic inflammation in COPD remains unknown.	25135745
Primary malignant neoplasm, Gastrointestinal inflammation	Altered Intercellular Communication	Faecal calprotectin (FC) is a surrogate marker for intestinal inflammation but not cancer.	25135754
Inflammation, CNS disorder	Altered Intercellular Communication	Conversely, in other CNS disorders signals from stressed cells may help control inflammation and inhibit degeneration.	25135977
Inflammation, liposarcoma, Lipoma, Hyperplasia	Altered Intercellular Communication	It was found that Eag1 was aberrantly expressed in over 67% liposarcomas, with a higher frequency than in lipoma, hyperplasia, inflammation, and normal adipose tissues.	25136578
Inflammation, Epithelial, Corneal Opacity, Corneal Neovascularization	Altered Intercellular Communication	We analyzed the best corrected visual acuity, epithelial defects, inflammation, corneal opacity, and corneal neovascularization.	25136628
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Elevated endostatin levels in CRC correlate with systemic inflammation and invasion through the muscularis propria.	25137019
Inflammation	Altered Intercellular Communication	Thus, iron detection with MRI might provide a biomarker for chronic inflammation within lesions.	25137340
Esophageal Stricture, Inflammation	Altered Intercellular Communication	Repeated blister formation and ulceration, coupled with chronic inflammation, result in scarring and development of esophageal strictures.	25138121
Inflammation, Pathology	Altered Intercellular Communication	In the non-industrialized countries of Africa and Asia obstetric fistulas are more frequently caused by prolonged labour, whereas in countries with developed healthcare systems they are generally the result of complications of gynaecological surgery or, rarely, benign pathologies like inflammation or foreign bodies.	25138359
Communicable Diseases, Inflammation, Anemia	Altered Intercellular Communication	Further research is needed on the effect of chronic inflammation and infectious disease on anaemia in elderly women in rural China.	25138800
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The main indications for PET/CT were: characterization of an indeterminate mass on radiological imaging, suspicion or staging of malignancy, and suspicion of inflammation.	25139518
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Vital exhaustion, but not inflammation, partly mediated the association between a small social network and incident stroke.	25139878
Inflammation, Diabetes Mellitus, Non-alcoholic Fatty Liver Disease, Napping, Fatty Liver Disease	Altered Intercellular Communication	Both longer habitual day napping and Non-Alcoholic Fatty Liver Disease (NAFLD) are associated with diabetes and inflammation, but the association between day napping and NAFLD remains unexplored.	25140521
Vasculitis, Fibrosis Assessment	Altered Intercellular Communication	The histopathological findings comprise bizarre basophilic multinucleated cells (MC), small vessel inflammation, mild dermal fibrosis, and a sparse lymphohistiocytic infiltrate.	25140659
Inflammation, Hemorrhage, Drug Implant, Dental Plaque, Osteopenia	Altered Intercellular Communication	Gender, age, plaque index, gingival inflammation, keratinized mucosa, probing depth, bleeding, and implant loss data were recorded, and periapical radiographs were obtained for measurement of marginal bone loss.	25141015
Gingivitis, Dental Plaque, Osteopenia	Altered Intercellular Communication	Correlations were found between bone loss and plaque index and between bone loss and gender, but bone loss did not correlate with gingival inflammation, keratinized mucosa, probing depth, or age.	25141015
Pancreatitis	Altered Intercellular Communication	Consistently high serum ghrelin values during pancreatic inflammation suggest that ghrelin may be used as an adjunctive parameter in the monitoring of the course of the disease.	25141321
Inflammation	Altered Intercellular Communication	The positive stains were often located in deep pyloric glands and associated with chronic inflammation patterns (p = 0.045).	25141489
Barrett Esophagus, Inflammation	Altered Intercellular Communication	A more advanced form of inflammation and Barrett's esophagus was found only in patients over 45 years of age.	25141579
Inflammation	Altered Intercellular Communication	The presence of H. pylori infection was varied in the different types of inflammation.	25141579
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	In all patients, in whom biopsy specimens were taken from normal duodenal mucosa (14% of patients), histopathological examination revealed the presence of non-specific inflammation, regardless of the coexistence of H. pylori infection.	25141579
Inflammation, Abnormal degeneration	Altered Intercellular Communication	We examined serum for 20 biomarkers of inflammation, tissue degeneration, and repair.	25141594
Inflammation, Disorder of tendon	Altered Intercellular Communication	These results suggest that early onset tendinopathy with concurrent inflammation may be occurring in prolific texters.	25141594
Inflammation, Diabetes Mellitus, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation and vagally mediated heart rate variability (vmHRV) have been implicated in a number of conditions including diabetes and cardiovascular disease.	25141771
Inflammation, Disease	Altered Intercellular Communication	Interventions targeted at vmHRV might be useful in the prevention of diseases associated with elevated systemic inflammation.	25141771
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	Antrum samples presented higher degrees of atrophy, intestinal metaplasia, chronic inflammation and neutrophil activity.	25142169
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	CagA genotype was significantly associated with higher degrees of intestinal metaplasia, neutrophil activity, chronic inflammation and OLGIM stages.	25142169
Refractory anemias, Inflammation	Altered Intercellular Communication	It indicates that CyPA may be involved in the regulation of the onset and development of inflammation process of RA.	25142855
Communicable Diseases, Inflammation	Altered Intercellular Communication	The presence of active inflammation or infection as suggested by an elevated ESR may negatively impact mobilization.	25143186
Gastrointestinal inflammation	Altered Intercellular Communication	Iron fortification adversely affects the gut microbiome, increases pathogen abundance and induces intestinal inflammation in Kenyan infants.	25143342
Diarrhea, Gastrointestinal inflammation	Altered Intercellular Communication	Secondary outcomes included faecal calprotectin (marker of intestinal inflammation) and incidence of diarrhoea.	25143342
Gastrointestinal inflammation	Altered Intercellular Communication	In this setting, provision of iron-containing MNPs to weaning infants adversely affects the gut microbiome, increasing pathogen abundance and causing intestinal inflammation.	25143342
Non-alcoholic Fatty Liver Disease, Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	Nonalcoholic fatty liver disease (NAFLD) - a new factor that interplays between inflammation, malnutrition, and atherosclerosis in elderly hemodialysis patients.	25143715
Malnutrition, Obesity	Altered Intercellular Communication	In contrast to the general population for whom overnutrition or obesity is associated with increased cardiovascular risk, for patients who are maintained on hemodialysis (HD), malnutrition and malnutrition-inflammation complex syndrome are associated with poor outcome.	25143715
Inflammation, Malnutrition, Atherosclerosis, HD Term Type, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Our results indicated that NAFLD probably interplays between inflammation, malnutrition, and atherosclerosis in elderly HD patients.	25143715
Inflammation, Lymphoma	Altered Intercellular Communication	Despite its success in diagnosing and staging lymphoma, F-FDG PET/CT can be falsely positive in areas of posttreatment inflammation.	25144214
Inflammatory Bowel Diseases, Crohn Disease, Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn's disease (CD), is an uncontrolled chronic inflammation of the gastrointestinal tract caused by an interaction of diverse genes and environmental factors.	25145003
Inflammation	Altered Intercellular Communication	Histologically, the lesion showed chronic inflammation with a deposition of fiber-like foreign bodies.	25145411
Inflammation	Altered Intercellular Communication	The origin of these fiber-like foreign bodies remains unclear but might be related to chronic inflammation resulting from intratracheal intubations.	25145411
Inflammation, Endothelial dysfunction, Chronic Kidney Diseases	Altered Intercellular Communication	In CKD, uremic solutes may induce endothelial dysfunction, inflammation, and oxidative stress, leading to increased cardiovascular risk.	25145928
Suppuration, Granulomatous inflammation	Altered Intercellular Communication	Histology showed florid, suppurative, granulomatous inflammation in the dermis, with central microabscess formation surrounded by epithelioid histiocytes, scattered giant cells, and a small number of lymphocytes.	25147085
ARCN1 gene, airway disease, Airway structure, Chronic Obstructive Airway Disease, Bronchitis	Altered Intercellular Communication	Chronic Obstructive Pulmonary Disease (COPD) is a progressive airway disease characterised by neutrophilic airway inflammation or bronchitis.	25148049
Granuloma, Sarcoidosis, Inflammation	Altered Intercellular Communication	Granulomas consisting of macrophages with multinucleated giant cells and sparse lymphocytic inflammation are confined to the subcutaneous tissue, rather than to their usual location within the dermis in typical lesions of cutaneous sarcoidosis.	25148276
Inflammation	Altered Intercellular Communication	The data suggest that intrathecal administration of novel therapeutic agents targeting immune cells outside of the proliferation cycle may be necessary to effectively eliminate intrathecal inflammation in progressive MS.	25148387
Refractory anemias, BARRIER	Altered Intercellular Communication	In vitro modeling of reactive astrocytes resulted in increased expression of RALDH2, enhanced RA synthesis, and a protective role for astrocyte-derived RA on BBB function during inflammation-induced barrier loss.	25149081
Refractory anemias	Altered Intercellular Communication	Furthermore, RA induces endothelial immune quiescence and decreases monocyte adhesion under inflammatory conditions.	25149081
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Human amylin oligomerizes quickly when oversecreted, which is toxic, induces inflammation in pancreatic islets and contributes to the development of T2D.	25149184
Communicable Diseases, Inflammation, Ischemic stroke, Neoplasms	Altered Intercellular Communication	The following causes were evaluated and ruled out: tumor, infection, ischemic stroke, non-infectious inflammation.	25149958
Colitis	Altered Intercellular Communication	P-317 (0.1mg/kg, ip and 1mg/kg, po) alleviated colonic inflammation in TNBS- and DSS-treated mice in the opioid receptor-dependent manner.	25149976
Depressive disorder, Depression, CTCAE	Altered Intercellular Communication	Clinical characteristics of inflammation-associated depression: Monocyte gene expression is age-related in major depressive disorder.	25150007
Eosinophilic inflammation	Altered Intercellular Communication	The FeNO levels in healthy school-aged children may reflect airway eosinophilic inflammation levels, and was affected by eosinophil count and age significantly.	25150075
Inflammation	Altered Intercellular Communication	RHEUMDOC: a one-page RHEUMatology DOCtor form with four physician global estimates for overall status, inflammation, damage, and symptoms based on neither inflammation nor damage.	25150341
Inflammation, Fibromyalgia, Chronic pain, Somatization	Altered Intercellular Communication	We sought to clarify a global summary of patient status by supplementing DOCGL with three additinal separate (0-10) physician global estimates for inflammation (DOCINF), damage (DOCDAM), and neither inflammation nor damage (DOCNON) (often fibromyalgia, but may be other chronic pain or somatization syndromes).	25150341
Inflammation	Altered Intercellular Communication	These data indicate face validity of the three physician global estimates on subscales for inflammation, damage, and symptoms due to neither inflammation nor damage.	25150341
Inflammation, Demyelination	Altered Intercellular Communication	Stereotactic brain biopsy revealed acute demyelination and B-cell dominated inflammation.	25150761
Cholecystitis, Inflammation	Altered Intercellular Communication	All 10 AC patients coexisted with GBC harbored "significantly inflamed' gallbladders, and about 83.49% AC patients were judged with "significant inflammation."	25151466
Autoimmune Diseases, Myositis	Altered Intercellular Communication	Polymyositis/dermatomyositis (PM/DM) is an autoimmune disease characterised by skin and muscle inflammation, internal organ involvement and serum disease-specific autoantibodies.	25151986
Inflammation, Contracture	Altered Intercellular Communication	Inflammation and skin-involvement are significant contributing factors for the development of contractures.	25152080
Corneal Neovascularization, Keratitis, Glaucoma, CTCAE, Ocular surface disease	Altered Intercellular Communication	Multivariate Cox regression analysis was performed, which adjusted for: age, sex, risk factors for graft failure (corneal neovascularization, ocular surface disease, glaucoma, active corneal inflammation, anterior synechiae), donor endothelial cell count, and repeat donor size.	25152499
Inflammation, Nasal Polyps, Common Cold, Allergic	Altered Intercellular Communication	Although polyps seem to be a manifestation of chronic inflammation in both allergic and non-allergic subjects, the pathogenesis of nasal polyposis remains unknown.	25153104
Hypergammaglobulinemia, Chronic inflammation	Altered Intercellular Communication	Protein electrophoresis revealed hypergammaglobulinemia consistent with chronic inflammation.	25153278
ARCN1 gene, Inflammation, Comorbidity, Obesity	Altered Intercellular Communication	To characterize the distribution of BMI in a population-based sample of COPD patients and to evaluate the impact of obesity on their health status, exercise tolerance, systemic inflammation and comorbidity.	25153331
ARCN1 gene, Inflammation, Obesity, Cardiovascular system	Altered Intercellular Communication	Furthermore, obesity affects the clinical manifestations, quality of life and exercise tolerance of COPD patients, and it may contribute to a phenotype characterized by increased systemic inflammation and greater frequency of cardiovascular comorbidity.	25153331
Inflammatory abnormality of the eye	Altered Intercellular Communication	The authors report two cases of chronic ocular inflammation with a novel sign of a prefoveal white vitreous condensation.	25153658
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor (TNF)-a, a key inflammatory cytokine responding to chronic inflammation of GBC, has been reported to stimulate the expression of VEGF-C in some nonneoplastic cells.	25154789
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Studies have shown that both cystatin C and metabolic syndrome (MetS) are associated with inflammation.	25155006
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is associated with local and systemic inflammation.	25155252
Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis	Altered Intercellular Communication	Crohn's disease (CD) and ulcerative colitis (UC) are the two major forms of inflammatory bowel diseases (IBD), which are defined as relapsing inflammations of the gastrointestinal tract.	25155925
Inflammation, Diabetic Polyneuropathies, Impaired	Altered Intercellular Communication	Higher levels of soluble CD163 in people with diabetic polyneuropathy suggest that inflammation plays a role in the development of neural impairment.	25156085
Inflammation, Hypothyroidism, Atherosclerosis	Altered Intercellular Communication	Recent studies have shown associations of hypothyroidism with arterial blood pressure, atherosclerosis, and inflammation.	25156414
Inflammation, Atherosclerosis, Hypothyroidism, Hypertension, CTCAE, Microcirculatory Bed, GTP-Binding Nuclear Protein Ran, Human	Altered Intercellular Communication	Based on these pathways, there might also be an association between hypothyroidism and retinal arteriolar narrowing (RAN), a marker of microvascular damage from hypertension, atherosclerosis, and inflammation.	25156414
Inflammation, Hypertension, CTCAE, atherosclerotic	Altered Intercellular Communication	Potential mechanisms explaining this association are long-term hypertension, atherosclerotic processes, and inflammation.	25156414
Inflammation, Gastritis, Atrophic	Altered Intercellular Communication	There was significantly more inflammation and atrophy in H. pylori-positive patients, but PGV did not influence the grade of gastritis.	25157752
Inflammation, ovarian neoplasm	Altered Intercellular Communication	Pre-diagnostic serum levels of inflammation markers and risk of ovarian cancer in the prostate, lung, colorectal and ovarian cancer (PLCO) screening trial.	25158036
ovarian neoplasm	Altered Intercellular Communication	Pre-diagnostic serum levels of 46 inflammation-related biomarkers (11 with a priori hypotheses; 35 agnostic) were measured in 149 incident ovarian cancer cases and 149 matched controls.	25158036
Inflammation, GYPB gene, Dry Eye Syndromes	Altered Intercellular Communication	In conclusion, dry eye syndrome in SS patients is associated with an altered proteomic profile with dysregulated expression of proteins involved in a variety of important cellular process including inflammation, immunity, and oxidative stress.	25159733
Inflammation, Arthritis, Obesity	Altered Intercellular Communication	This study suggests that there may be interplay between obesity, inflammation, and otherwise unexplained arthritis and highlights a previously unrecognized complication of childhood obesity.	25160015
Cholelithiasis, Colitis	Altered Intercellular Communication	Metabolic phenotyping was also able to distinguish between cholelithiasis and colonic inflammation among the heterogeneous non-AP group.	25160714
Inflammation, Malnutrition, Anemia	Altered Intercellular Communication	No features suggestive of malnutrition, severe anemia, inflammation, or inadequate dialysis were detected.	25161116
Inflammation, Doxorubicin/Thiotepa/Vinblastine	Altered Intercellular Communication	All BAV patients showed significantly less inflammation (P < 0.001) and an altered intima/media ratio when compared with TAV patients.	25161185
Inflammation	Altered Intercellular Communication	We hypothesized that Sirt6, which is a nuclear, chromatin-bound protein critically involved in many pathophysiologic processes such as aging and inflammation, may have a role in oxidative stress-induced vascular cell senescence.	25162034
Pneumonitis, Neoplasms	Altered Intercellular Communication	A variety of 25 cytokines linked to pulmonary inflammation and tumor development were found significantly associated with Asb-workers and MM patients compared with healthy controls.	25162674
Inflammation, Inflammatory cardiomyopathy	Altered Intercellular Communication	Intramyocardial inflammation is considered an adverse prognostic factor in inflammatory cardiomyopathy (CMi).	25163698
Myocarditis	Altered Intercellular Communication	In EMBs, myocardial inflammation was assessed by histology and immunohistology.	25163698
Inflammation, Mucoid degeneration, Hemosiderin	Altered Intercellular Communication	The PCLs were graded histologically in terms of parallel orientation of collagen fibres, mucoid degeneration, inflammation, and haemosiderin deposition.	25163942
Inflammation	Altered Intercellular Communication	Most commonly, it is the result of epithelial proliferation, but it can also be caused by inflammation or obstruction of the appendix.	25163976
Inflammation	Altered Intercellular Communication	ER stress may trigger both inflammation and oxidative stress processes.	25164487
Inflammation, Chronic disease	Altered Intercellular Communication	Therefore, interventions that reduce chronic disease risk factors (i.e., blood pressure, chronic inflammation, and cortisol) are important in this population.	25164513
Infection, Pneumonia	Altered Intercellular Communication	Pneumonia is an inflammatory condition of lung caused by infections, which may be triggered and exacerbated by PMc exposure.	25164925
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Inflammation is a major risk factor for development of colorectal cancer (CRC).	25166592
Inflammation	Altered Intercellular Communication	Prostaglandin synthase cyclooxygenase-2 (COX-2) encoded by the PTGS2 gene is the rate limiting enzyme in prostaglandin synthesis and therefore plays a distinct role as regulator of inflammation.	25166592
Airway structure, Asthma	Altered Intercellular Communication	However, the relationship between exhaled H2 S and airway inflammation phenotypes in asthma remains unclear.	25168466
neutrophilic, Inflammation	Altered Intercellular Communication	The eosinophilic, neutrophilic, mixed granulocytic and paucigranulocytic inflammation groups included 57 (38.5%), 28 (18.9%), 23 (15.5%) and 40 (27%) subjects, respectively.	25168466
Airway structure, Asthma	Altered Intercellular Communication	Exhaled H2 S may be a useful marker of airway inflammation in asthma.	25168466
Pain Distress Question, Inflammation, Knee pain	Altered Intercellular Communication	To assess the association between pain mechanisms (sensitization) and biochemical markers for cartilage, bone, and inflammation in patients with knee pain.	25168637
Inflammation, Central pain	Altered Intercellular Communication	This study showed significant correlations between central pain sensitization and CRPM as a possible measure for chronic inflammation.	25168637
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver fibrosis stage and inflammation grade were evaluated by Metavir and Scheuer scoring systems, respectively.	25168642
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	The severity of liver inflammation was independently related to moderate to severe fibrosis (F >=2).	25168642
Fibrosis, Liver, Hepatitis	Altered Intercellular Communication	Liver inflammation is closely related to the development of moderate to severe liver fibrosis.	25168642
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	These glycans also correlated significantly with lobular inflammation, ballooning, and fibrosis, but not with steatosis.	25168691
Neuromyelitis Optica, Myelitis, Transverse, N-nitrosomorpholine, Optic Neuritis	Altered Intercellular Communication	Neuromyelitis optica (NMO) is an autoimmune inflammatory condition of the central nervous system that is characterized by circulating anti-aquaporin-4 antibodies, transverse myelitis and optic neuritis.	25169022
Inflammation, Atherosclerosis	Altered Intercellular Communication	Increased microvascularization and vessel permeability associate with active inflammation in human atheromata.	25170063
Hereditary Autoinflammatory Diseases, Inflammation, Ventricular arrhythmia, Atherosclerosis, Brucellosis, Familial Mediterranean Fever	Altered Intercellular Communication	Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disease associated with subclinical inflammation, which includes atherosclerosis arising from endothelial inflammation, which in turn increases the risk of atrial or ventricular arrhythmias.	25170297
Prostate carcinoma, prostatitis	Altered Intercellular Communication	Prostate volume index and chronic inflammation of the prostate type IV with respect to the risk of prostate cancer.	25170543
Inflammation, Injury of cardiac valve, Electrocardiogram: myocardial infarction (finding), No-Reflow Phenomenon, Neurocirculatory Asthenia	Altered Intercellular Communication	Improved endothelial function, reduced low grade inflammation and decreased thrombotic diathesis might reduce cardiac injury, diffuse cardiac necrosis, myocardial infarction and no-reflow phenomenon.	25170586
Barrett Esophagus, Inflammation, Gastro-esophageal reflux disease with esophagitis, Intestinal metaplasia	Altered Intercellular Communication	Reflux esophagitis (RE) is characterized by inflammation of the squamous epithelium (SQ) of the esophagus and may progress to Barrett's esophagus (BE) characterized by intestinal metaplasia.	25170842
Inflammation	Altered Intercellular Communication	The role of inflammation in this transition has been postulated but lacks experimental evidence.	25170842
Kidney Failure, Chronic, Inflammation, Immunologic Deficiency Syndromes	Altered Intercellular Communication	End-stage renal disease (ESRD) is simultaneously associated with immune activation, systemic inflammation and immune deficiency.	25171218
Neoplasms, Autoimmune limbic encephalitis	Altered Intercellular Communication	Autoimmune limbic encephalitis is an inflammatory condition often associated with an underlying neoplasm.	25171259
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Attenuated expression of BRINP3 in UC was independent of current inflammation, unrelated to phenotype or treatment, and remained low at rebiopsy an average of 22 months later.	25171508
Inflammation	Altered Intercellular Communication	Low levels of this gene could predispose or contribute to the maintenance of the characteristic mucosal inflammation seen in this condition.	25171508
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	These Th17 cells are considered important in intestinal inflammation, such as seen in Crohn's disease (CD).	25172498
Forsythia	Altered Intercellular Communication	Furthermore, hemoglobin levels were associated with the detection of T. forsythia and neutrophil activation/inflammation markers.	25173070
Inflammation, Injury of liver	Altered Intercellular Communication	Our results suggested that decreased serum fibronectin levels in patients with ACHBLF were correlated to hepatic injury and inflammation.	25173344
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	The aim of this study was to determine whether physical activity level was associated with inflammation or insulin resistance during a 5-year period in outpatients with known CHD.	25173442
Inflammation	Altered Intercellular Communication	Lipoprotein-associated phospholipase A2 (Lp-PLA2) has been hypothesized to be involved in atherogenesis through pathways related to inflammation.	25173516
Fibrosis Assessment	Altered Intercellular Communication	Thus, periostin might play an important role in a vicious circle (aging-fibrosis-inflammation-aging) of heart through promoting myocardial fibrosis and cardiomyocyte senescent simultaneously.	25173938
Inflammation, Carcinogenesis, Injury of liver	Altered Intercellular Communication	Haematopoietic cell-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injury.	25173965
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	Inflammation is a common event in the pathogenesis of liver cirrhosis.	25173967
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	The inflammasome pathway has acquired significant relevance in the pathogenesis of inflammation, but its role in the inflammatory response in patients with decompensated cirrhosis remains unexplored.	25173967
Acute inflammation	Altered Intercellular Communication	Evaluation of hepatocyte growth factor as a local acute phase response marker in the bowel: the clinical impact of a rapid diagnostic test for immediate identification of acute bowel inflammation.	25174881
Inflammation	Altered Intercellular Communication	It has high affinity to sulfated glycan, and this binding affinity is lost during chronic inflammation.	25174881
Acute inflammation	Altered Intercellular Communication	HGF is a good local acute phase response marker of acute bowel inflammation.	25174881
Intraocular inflammation, Aniridia	Altered Intercellular Communication	Compared to patients with KPro retention, those requiring KPro explantation were associated with aniridia (P = .0038), sterile keratolysis (P < .001), retroprosthesis membrane (P = .02), and intraocular inflammation (P = .04).	25174898
Alzheimers Disease	Altered Intercellular Communication	One case of Alzheimer's disease for which a brain biopsy was performed showed CAA-related inflammation.	25175137
Inflammation, Fever, CTCAE, Brucellosis, Autosomal Recessive Disorder, Familial Mediterranean Fever	Altered Intercellular Communication	Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by periodic fever and serosal inflammation.	25175140
Inflammation, Mesothelioma	Altered Intercellular Communication	Because asbestos can cause chronic inflammation at the pleural and peritoneal surfaces we hypothesised that NSAID and COX-2 inhibitors would inhibit the development of asbestos-induced mesothelioma.	25175318
ARCN1 gene, Inflammation	Altered Intercellular Communication	Mobile-phone-based home exercise training program decreases systemic inflammation in COPD: a pilot study.	25175787
Inflammation	Altered Intercellular Communication	Decreased systemic inflammation may contribute to these clinical benefits.	25175787
Communicable Diseases, Neurologic Deficits, Inflammation, Deformity of facial bone	Altered Intercellular Communication	The majority of complications were infection and inflammation (36.4%), followed by neurological deficit (24.0%), physiological dysregulation (11.6%) and facial bone deformity (8.3%).	25176495
Arthritis	Altered Intercellular Communication	Distribution of interleukin-10 family cytokines in serum and synovial fluid of patients with inflammatory arthritis reveals different contribution to systemic and joint inflammation.	25178435
Inflammation	Altered Intercellular Communication	Therefore, IL-19 seems to be involved mainly in the joint inflammation, whereas IL-20 and IL-24 appear to participate mainly in the systemic responses.	25178435
Primary gout, Gout	Altered Intercellular Communication	Based on the role of apoA-I in anti-inflammation, our observational data in acute gout support the hypothesis that apoA-I expression can be induced under the condition of a high concentration of UA and its elevated level may be implicated in the spontaneous resolution of acute gouty arthritis.	25178483
Inflammation, Electrocardiogram: myocardial infarction (finding), Angina Pectoris	Altered Intercellular Communication	Differences determined by optical coherence tomography volumetric analysis in non-culprit lesion morphology and inflammation in ST-segment elevation myocardial infarction and stable angina pectoris patients.	25178981
Inflammation	Altered Intercellular Communication	The novel OCT-based 3-D quantification of the FC and macrophage demonstrated thinner FC thickness and larger areas of TCFA coupled with more inflammation in non-culprit sites of STEMI compared with SAP.	25178981
Inflammation, Heart failure, Bipolar Disorder	Altered Intercellular Communication	Depressive symptoms and the relationship of inflammation to physical signs and symptoms in heart failure patients.	25179036
Inflammation, Heart failure, Bipolar Disorder	Altered Intercellular Communication	Depressive symptoms in patients with heart failure can affect the relationship between physical signs and symptoms and inflammation.	25179036
Inflammation, Heart failure, Bipolar Disorder	Altered Intercellular Communication	Both depressive symptoms and inflammation should be considered along with physical signs and symptoms in patients with heart failure.	25179036
Inflammation, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is a disease characterized by inflammation in the arterial wall.	25179298
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Evidences indicate that oxidative stress and inflammation are important processes in the development of destructive synovial tissue in rheumatoid arthritis (RA).	25179377
Inflammation	Altered Intercellular Communication	The two major bioscavenger enzymes that are associated with inflammation and oxidative stress are human-butyrylcholinesterase (BuChE) and paraoxonase-1 (PON-1).	25179377
Refractory anemias, Rheumatoid Arthritis, Inflammation, Hyperplasia	Altered Intercellular Communication	Rheumatoid arthritis (RA) is characterized by chronic synovial inflammation and hyperplasia.	25179850
Inflammation, Osteopenia	Altered Intercellular Communication	Cements that tend to leave more undetected excess have a higher prevalence for peri-implant inflammation and cause a more severe peri-implant bone loss.	25180598
Cessation of life, Inflammation	Altered Intercellular Communication	Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation.	25180606
Cessation of life, Inflammation, Peritonitis	Altered Intercellular Communication	Pharmacological inhibition or knockdown of PR3 delayed neutrophil death in vitro and consistently delayed neutrophil death and augmented neutrophil accumulation at sites of inflammation in a murine model of peritonitis.	25180606
Inflammation, Fibrosis Assessment, IgG4-Related Sclerosing Disease	Altered Intercellular Communication	IgG4-related disease (IgG4-RD) is a new disease entity characterized by type 2 helper T (Th2)-dominant inflammation and progressive fibrosis.	25180614
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In conclusion, we found the remarkable infiltration of C/EBPa(+)M2 macrophages in cases of chronic inflammation with fibrosis, including IgG4-RD.	25180614
Inflammation, Osage language, Cardiovascular Diseases	Altered Intercellular Communication	The increment of systemic inflammation in OSA has been considered as the major pathogenic mechanism leading to cardiovascular diseases.	25180986
Inflammation, Osage language, Cardiovascular Diseases	Altered Intercellular Communication	Elevated plasma MPO activity and sTNF-R1 levels in the OSA patients indicate increased systemic inflammation and oxidative stress which might contribute to the higher incidence of cardiovascular diseases.	25180986
Granulomatous inflammation, Myxoma	Altered Intercellular Communication	Histopathologic examination of valve tissue and the myxoma revealed granulomatous inflammation and large numbers of organisms in most specimens.	25181311
Fibrosis Assessment, Hepatitis B, Hepatitis	Altered Intercellular Communication	Soluble CD163 is an indicator of liver inflammation and fibrosis in patients chronically infected with the hepatitis B virus.	25181653
Fibrosis Assessment, Hepatitis, Hepatitis B, Chronic	Altered Intercellular Communication	The aim of the current study was to investigate whether serum sCD163 levels correlate with liver inflammation and fibrosis in patients with chronic hepatitis B virus (HBV) infection.	25181653
Deafness, Sudden	Altered Intercellular Communication	The slight asymmetry might indicate a greater vulnerability of the left inner ear in women, suggesting hormonal factors in the genesis of sudden deafness.	25181661
Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Congestive heart failure, Dystrophic calcification, Chronic heart failure	Altered Intercellular Communication	Inflammation and dystrophic calcification have been associated with cardiovascular disease (CVD) and chronic heart failure (CHF).	25181915
Inflammation	Altered Intercellular Communication	Dietary fats have been shown to promote the translocation of bacterial endotoxins from the gut into circulation, which may induce systemic inflammation and modulate the inflammatory response of circulating immune cells.	25182144
Inflammation, Encephalopathy, CTCAE 5.0, DHDDS gene	Altered Intercellular Communication	HMGB1, as an important late mediator of inflammation, is involved in the inflammatory reaction in delayed encephalopathy, and is positively correlated with HDS and ADL scores, indicating that it can be used as one of the major indicators in monitoring carbon monoxide poisoning.	25182828
vascular inflammations, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Platelet-derived products appear to dominate the inflammatory response during ACS, adding to the emerging evidence that ACS per se may promote vascular inflammation.	25183015
Inflammation	Altered Intercellular Communication	Serum ALT and AST, but not plasma M30 showed a significant trend with increasing grades of ballooning and lobular inflammation.	25184298
IgG4-Related Sclerosing Disease, Pseudolymphoma, Immunoglobulin G4-Related Disease, Orbital Pseudotumor	Altered Intercellular Communication	To determine the proportion of idiopathic orbital inflammation (IOI) and orbital benign lymphoid hyperplasia (OBLH) accounted for by immunoglobulin (Ig)G4-related orbital disease (IgG4-ROD) using the comprehensive diagnostic criteria for IgG4-related disease published by Umehara et al and the consensus diagnostic criteria published by Deshpande et al.	25185258
Lymphoid hyperplasia, IgG4-Related Sclerosing Disease, Orbital Pseudotumor	Altered Intercellular Communication	An analysis of IgG4-related disease (IgG4-RD) among idiopathic orbital inflammations and benign lymphoid hyperplasias using two consensus-based diagnostic criteria for IgG4-RD.	25185258
Inflammation, Molluscum Contagiosum, Sezary Syndrome, Eczema	Altered Intercellular Communication	We report the original observation of a patient with stage IV Sezary syndrome, who presented multiple molluscum contagiosum, spread and surrounded by a pale halo, without inflammation, eczema or disappearance of melanocytes.	25186152
Inflammation, Molluscum Contagiosum	Altered Intercellular Communication	This halo could be due to the secretion of a protein by molluscum contagiosum inhibiting inflammation around this MC.	25186152
Inflammation	Altered Intercellular Communication	These features might help to quantify the degree of inflammation in inflammatory skin conditions.	25186162
Inflammation, Hyperglycemia, Diabetes Mellitus	Altered Intercellular Communication	Inflammation and hyperglycemia mediate Deaf1 splicing in the pancreatic lymph nodes via distinct pathways during type 1 diabetes.	25187368
Inflammation, Hyperglycemia	Altered Intercellular Communication	Inflammation and hyperglycemia independently drive Deaf1 splicing through activation of the splicing factors Srsf10 and Ptbp2, respectively.	25187368
Inflammation	Altered Intercellular Communication	Inflammation induced by injection of activated splenocytes increased Deaf1-Var1 and Srsf10, but not Ptbp2, in the PLNs of NOD.SCID mice.	25187368
Inflammation, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8, Hyperglycemia	Altered Intercellular Communication	These data suggest that during the progression of T1D, inflammation and hyperglycemia mediate the splicing of DEAF1 and loss of PTA expression in LNSCs by regulating the expression of SRSF10 and PTBP2.	25187368
Inflammation	Altered Intercellular Communication	Clinical evaluation of multiple inflammation biomarkers for diagnosis and prognosis for patients with systemic inflammatory response syndrome.	25187630
Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	A multiplexed biomarker bundle consisting of nine different inflammation markers was evaluated regarding their diagnostic and prognostic performances in 159 adult systemic inflammatory response syndrome (SIRS) patients enrolled at the emergency department.	25187630
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Cumulative inflammation associates with asymmetric dimethylarginine in rheumatoid arthritis: a 6 year follow-up study.	25187642
Refractory anemias, Inflammation	Altered Intercellular Communication	Two hundred and one RA patients [155 females, median age 67 years (range 59-73)] were assessed at baseline (2006) for the presence of classical CVD risk factors and determination of systemic inflammation by CRP and ESR.	25187642
Hidradenitis Suppurativa, Inflammation	Altered Intercellular Communication	Hidradenitis suppurativa (HS) is a disease characterized by chronic follicular occlusion and secondary inflammation of the apocrine glands.	25188457
Inflammation, Cryptitis	Altered Intercellular Communication	The most common finding on small intestinal biopsy (13/25 cases, 52%) was villous blunting, expansion of the lamina propria by mixed but predominantly mononuclear inflammation, and neutrophilic cryptitis with or without crypt microabscesses.	25188868
Inflammation, Acute GVH disease	Altered Intercellular Communication	Increased crypt apoptosis with minimal inflammation, resembling acute graft-versus-host disease, was observed in 4 cases (16%).	25188868
Inflammation, Intraepithelial Lymphocytosis, Acute GVH disease	Altered Intercellular Communication	Findings in non-small intestinal sites were variable and included mixed active and chronic inflammation, chronic inflammation alone, intraepithelial lymphocytosis, and increased apoptosis resembling acute graft-versus-host disease.	25188868
Inflammation, Enteritis	Altered Intercellular Communication	In summary, AIE most commonly presents as an active enteritis with villous blunting and expansion of the lamina propria by mixed inflammation.	25188868
Inflammation, Ketoacidosis	Altered Intercellular Communication	This inflammation led to poor insulin absorption, poorly controlled blood glucose and subsequently to ketoacidosis.	25188930
Inflammation, Primary malignant neoplasm, Carcinoma of lung, Inflammatory disorder	Altered Intercellular Communication	Similar fibroblast phenotypes in inflammatory diseases and cancer tissues suggested a correlation between inflammation and cancer and implied a common mechanism underlying the formation of fibroblasts in inflammatory diseases and lung cancer.	25189096
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Adipose tissue inflammation and perturbation of adipokine secretion may contribute to the pathogenesis of cardiovascular diseases (CVD).	25189569
vascular inflammations	Altered Intercellular Communication	EETs are potent endogenous vasodilators and inhibitors of vascular inflammation.	25189712
Klinefelter Syndrome, SLC22A5 gene	Altered Intercellular Communication	We can presume that adult men with SCD showed clinical hypoandrogenism with normal testicular hormonal function, a fact inconsistent with the hypothesis of primary hypogonadism.	25190051
Tumor necrosis, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Independent pathologic review of tumor necrosis and normal liver tissue grading of fibrosis and inflammation after resection was performed.	25190114
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In nontumor-bearing liver, fibrosis grade (0-4) and inflammation score (0-4) was 2 or less in all specimens.	25190114
Liver carcinoma	Altered Intercellular Communication	The C-reactive protein/albumin ratio, a novel inflammation-based prognostic score, predicts outcomes in patients with hepatocellular carcinoma.	25190127
FAM126A gene	Altered Intercellular Communication	The CRP/Alb ratio might be an independent prognostic marker in patients with HCC, and may have comparable prognostic ability to other established inflammation-based prognostic scores.	25190127
Primary malignant neoplasm	Altered Intercellular Communication	The prognostic value of this novel inflammation-based prognostic score needs to be verified in patients with other types of cancer.	25190127
Inflammation, Bacterial Infections	Altered Intercellular Communication	Similar to mucin O-glycosylation, protein N-glycosylation appears to be regulated primarily as a secondary effect of bacterial infection and inflammation rather than the CF pathogenesis in sputum.	25190359
Inflammation, Metabolic Syndrome X, Atherosclerosis, Chronic inflammatory disorder, Spondylitis	Altered Intercellular Communication	Since ankylosing spondylitis (AS) is a chronic inflammatory disease associated with accelerated atherosclerosis, we aimed to assess whether OPG levels correlate with disease activity, systemic inflammation, metabolic syndrome, adipokines and biomarkers of endothelial cell activation in patients with AS undergoing TNF-a antagonist therapy.	25190453
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Correlations of OPG levels with disease activity, clinical characteristics, systemic inflammation, metabolic syndrome features, adipokines and biomarkers of endothelial activation were assessed.	25190453
Inflammation, Depressive disorder, Metabolic Syndrome X, Schizophrenia	Altered Intercellular Communication	Metabolic syndrome and inflammation markers in patients with schizophrenia and recurrent depressive disorder.	25191767
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The levels of inflammation markers (i.e., C-reactive protein and PAI-1) were significantly higher among patients with metabolic syndrome.	25191767
Schizophrenia, Inflammation, Depressive disorder, Metabolic Syndrome X	Altered Intercellular Communication	Patients with schizophrenia and recurrent depressive disorder demonstrate a high prevalence of metabolic syndrome that is also related to inflammation processes.	25191767
ovarian neoplasm, Pelvic Inflammatory Disease	Altered Intercellular Communication	Pelvic inflammation and the pathogenesis of ovarian cancer: a cohort study.	25191876
ovarian neoplasm, Malignant Neoplasms, Pelvic Inflammatory Disease	Altered Intercellular Communication	The aim of this study was to determine whether pelvic inflammation contributes to the pathogenesis of ovarian cancer or other malignancies.	25191876
Malignant Neoplasms, Pelvic Inflammatory Disease	Altered Intercellular Communication	Eight hundred eighty-eight women with past pelvic inflammation, as diagnosed by characteristic findings at fertility surgery, and 552 women without were compared for the subsequent development of malignancy, during the period of 1981 to 2012.	25191876
ovarian neoplasm, Inflammation	Altered Intercellular Communication	The adjusted odds ratio for ovarian cancer, after past inflammation, was 5.56 (95% confidence interval, 0.52-59.40).	25191876
ovarian neoplasm, Pelvic Inflammatory Disease	Altered Intercellular Communication	Age-adjusted ovarian cancer incidence was significantly elevated among women with previous pelvic inflammation (standardized incidence ratio, 3.99; 95% confidence interval, 1.46-8.68).	25191876
ovarian neoplasm, Pelvic Inflammatory Disease	Altered Intercellular Communication	The rate of ovarian cancer was not significantly elevated in women with past pelvic inflammation compared with the controls.	25191876
ovarian neoplasm, Pelvic Inflammatory Disease	Altered Intercellular Communication	However, a significantly increased risk for ovarian cancer was apparent among women with pelvic inflammation when compared with the general population.	25191876
ovarian neoplasm, Pelvic Inflammatory Disease	Altered Intercellular Communication	Pelvic inflammation may be a contributory factor in the pathogenesis of ovarian cancer.	25191876
FCGR3A gene	Altered Intercellular Communication	Importantly, a single dose of NP001 caused a dose-dependent reduction in expression of monocyte CD16, a marker of monocyte activation/inflammation.	25192333
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	The potential for modulation of inflammation in the context of ALS disease progression will require further study with long-term follow-up.	25192333
Keratitis, Infiltration	Altered Intercellular Communication	Because other signs of corneal inflammation, such as stromal infiltration and ciliary injection, were lacking, the condition was left untreated.	25192915
Cardiac Arrest, Reperfusion Injury	Altered Intercellular Communication	The whole body ischaemia-reperfusion after cardiac arrest (CA) induces a systemic inflammation-reperfusion response.	25193800
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Interleukin 8 (IL-8), as a member of the CXC chemokine family, has a regulatory role in joint inflammation and cartilage degradation, and contribute to the pathophysiology of osteoarthritis.	25194757
Inflammation, Acute infectious disease	Altered Intercellular Communication	There is a positive correlation between the parameters of inflammation and glucoregulation in diabetics with acute infection.	25195343
Inflammation, Fibrosis Assessment, Prediabetes syndrome, Skeletal muscle structure	Altered Intercellular Communication	When well-matched for clinical parameters (BMI, total adiposity, or prevalence of prediabetes/type 2 diabetes), no significant differences were observed among groups in terms of skeletal muscle, hepatic, or adipose tissue insulin sensitivity, the amount of liver fat by (1)H-MRS, or the severity of histological inflammation, ballooning, or fibrosis.	25195551
metabolic disturbance	Altered Intercellular Communication	Impact of metabolic disturbances and malnutrition-inflammation on 6-year mortality in Japanese patients undergoing hemodialysis.	25196142
Sepsis, Inflammation, Breast Fibrocystic Change, Non-Proliferative Type, Communicable Diseases	Altered Intercellular Communication	Our results suggest predominance of a non-proliferative effector subset of gdT cells in patients with sepsis, which retain functional activity and may contribute towards the host response to inflammation and infection.	25196852
Primary malignant neoplasm, Chronic sinusitis, Craniosynostosis, Cancer of Nasopharynx	Altered Intercellular Communication	Although epidemiological and laboratory studies report that chronic inflammatory conditions contribute to the pathogenesis of cancer, it remains controversial whether chronic rhinosinusitis (CRS) results in nasopharyngeal cancer (NPC).	25197911
Malignant Lesion, Neoplasms	Altered Intercellular Communication	The median ADC value for the malignant lesions was 0.6 x 10(-3), whereas that for the inflammatory conditions was 1.6 x 10(-3) and that for the benign tumors was 1.5 x 10(-3) with a highly significant difference (p < .001).	25198015
Inflammation, myonecrosis, Reperfusion Injury	Altered Intercellular Communication	The postprocedural state after cardiac revascularization interventions is characterized by intense inflammation and activation of inflammatory cytokines due to myonecrosis and ischemia/reperfusion injury.	25198111
Hip joint pain, Bursitis	Altered Intercellular Communication	We hypothesised that trochanteric bursitis may not however have an inflammatory component and that accordingly, bursal inflammation has no role in lateral hip pain.	25198303
Inflammation, Long-term	Altered Intercellular Communication	Nineteen eyelids had implant-related complications: 7 with cyst formation, 7 with exposure/rejection, 2 with long-term pain, 2 with transient inflammation, and 3 with irregular implant contour.	25198397
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In addition, target gene prediction showed that these five altered miRNAs are involved in affecting various aspects of cardiac or vascular remodeling, especially in the pathway involving inflammation and fibrosis.	25198728
Inflammation, Dentigerous Cyst	Altered Intercellular Communication	There is an association between persistent, prolonged inflammation of a primary tooth and the development of an inflammatory dentigerous cyst involving the succedaneous tooth.	25198956
Inflammation, Colorectal Carcinoma, Colonic Polyps	Altered Intercellular Communication	Moreover, the cell wall of this bacterium may have low pathogenicity as well as cause chronic inflammation in the large intestine mucous membrane, colonic polyps, and colorectal cancer.	25199383
Inflammation, Unknown (origin) (qualifier value), iatrogenic injury, Traumatic injury, Deformity	Altered Intercellular Communication	Its etiology varies, including space occupying lesions, trauma, inflammation, anatomic deformity, iatrogenic injury, and idiopathic and systemic causes.	25199522
Sepsis, Inflammation, Thrombosis	Altered Intercellular Communication	The adjusted odds ratios for thrombosis were 2.5 (2.4 to 2.6) in patients with systemic inflammatory response syndrome, 3.3 (3.1 to 3.4) in patients with sepsis, and 5.7 (5.4 to 6.1) in patients with severe sepsis, compared with patients without any systemic inflammation.	25199629
Inflammation, Diffuse Large B-Cell Lymphoma, Chronic inflammation, Aggressive Non-Hodgkin Lymphoma	Altered Intercellular Communication	Diffuse large B-cell lymphoma (DLBCL) associated with chronic inflammation is a recently adopted category of DLBCL, which describes an aggressive B-cell lymphoma raised in the setting of non-immune chronic inflammation.	25199714
Inflammation, Pancreatic intraepithelial neoplasia	Altered Intercellular Communication	Lactate and taurine remained unchanged in inflammation and in pre-cancerous metaplasia but increased significantly in pancreatic intraepithelial neoplasia to 266 +- 61% (p = 0.0001) and 999 +- 174% (p < 0.00001) of controls, respectively.	25199993
Inflammation, Pancreatitis, Pancreatic intraepithelial neoplasia, Neoplasms	Altered Intercellular Communication	Based on these findings, we propose that a drop in lipid levels could serve to inform on pancreatitis and cancer-associated inflammation, whereas elevated lactate and taurine could serve to identify the presence of pancreatic intraepithelial neoplasia and invasive tumor.	25199993
Inflammation, Sleep Apnea, Obstructive, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	[Lower grade chronic inflammation is associated with obstructive sleep apnea syndrome in type 2 diabetes mellitus].	25200039
Inflammation, Sleep Apnea, Obstructive, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	To investigate whether the existence of obstructive sleep apnea syndrome (OSAS) in patients with type 2 diabetes (T2DM) is associated with low grade chronic inflammation.	25200039
Inflammation, Disorder of eye due to diabetes mellitus	Altered Intercellular Communication	BMP7 reduces inflammation and oxidative stress in diabetic tubulopathy.	25200314
Diabetic Nephropathy	Altered Intercellular Communication	Our results demonstrate that BMP7 attenuates tubular pro-inflammatory responses in diabetic kidney disease by suppressing oxidative stress and multiple inflammatory signalling pathways including p38 and p44/42 MAPK.	25200314
Inflammation	Altered Intercellular Communication	Interleukin-33 (IL-33) is an inflammatory cytokine that is constitutively expressed in barrier tissues such as skin and lung and up-regulated in inflammation.	25200795
Data types - Address	Altered Intercellular Communication	A growing awareness exists that pro-oxidative state and neuro-inflammation are both involved in AD.	25201785
Bacterial Translocation, Inflammation	Altered Intercellular Communication	Compared with OHAVR, TAVI was associated with decreases in bacterial translocation and inflammation.	25202829
Respiratory Hypersensitivity, allergic inflammation	Altered Intercellular Communication	Chronic low dose chlorine exposure aggravates allergic inflammation and airway hyperresponsiveness and activates inflammasome pathway.	25202911
Airway structure, Respiratory Hypersensitivity	Altered Intercellular Communication	Studies were undertaken to define the effects and mechanisms of chronic low-dose chlorine exposure in the pathogenesis of airway inflammation and airway hyperresponsiveness (AHR).	25202911
Airway structure	Altered Intercellular Communication	Airway inflammation and AHR were evaluated by bronchoalveolar lavage (BAL) cell recovery and non-invasive phlethysmography, respectively.	25202911
Airway structure, AHR wt Allele	Altered Intercellular Communication	Chronic low dose chlorine exposure significantly augmented airway inflammation and AHR in OVA-sensitized and challenged mice.	25202911
Allergic, AHR wt Allele, Inflammation	Altered Intercellular Communication	Chronic low dose exposure of chlorine aggravates allergic Th2 inflammation and AHR potentially through activation of inflammasome danger signaling pathways.	25202911
Inflammation, Liver damage	Altered Intercellular Communication	Heme oxygenase-1 (HO-1) is an inducible, detoxifying enzyme that is critical for limiting oxidative stress, inflammation, and cellular injury within the CNS and other tissues.	25202977
Inflammation	Altered Intercellular Communication	The skin biopsy showed a granulomatous inflammation with prominent plasma cells, consistent with granulomatous infiltrate.	25203547
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic systemic inflammation is common in patients with chronic kidney disease on dialysis (CKD5D) and has been considered a key mediator of the increased cardiovascular risk in this patient population.	25204316
Sjogrens Syndrome", Inflammation, Disease, PEELING SKIN SYNDROME	Altered Intercellular Communication	The red blood cell distribution width (RDW) and neutrophil/lymphocyte ratio (NLR) are increased in various inflammation related diseases, but their clinical significance in primary Sjogren's syndrome (pSS) has not been reported.	25204965
Inflammation, Pain Distress Question	Altered Intercellular Communication	Systemic biochemical markers of joint metabolism and inflammation in relation to radiographic parameters and pain of the knee: data from CHECK, a cohort of early-osteoarthritis subjects.	25205017
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	To investigate associations of biochemical markers of joint metabolism and inflammation with minimum joint space width (JSW) and osteophyte area (OP area) of knees showing no or doubtful radiographic osteoarthritis (OA) and to investigate whether these differed between painful and non-painful knees.	25205017
Inflammation, Fibrous, Necrosis	Altered Intercellular Communication	On histologic examination, there were regions of fat necrosis without inflammation or increased vascularity, surrounded by fibrous walls.	25205027
Bone Cysts, Fibrous, Inflammation, Necrosis	Altered Intercellular Communication	In contrast to previous reports that described a mucoid composition of intracarpal bone cysts with occasional foamy macrophages, our observations support the concept that these lesions reflect a spectrum of fat necrosis and fibrous changes, without inflammation or hypervascularity.	25205027
Inflammation, Albuminuria	Altered Intercellular Communication	Chronic inflammation despite potent antiretroviral treatment may contribute to higher rates of albuminuria among HIV-infected patients.	25205472
Sepsis, Pancreatic stone, Inflammation	Altered Intercellular Communication	Pancreatic stone protein/regenerating protein has recently emerged as an interesting diagnostic and prognostic marker of inflammation and sepsis in the clinical field.	25205512
Orchitis	Altered Intercellular Communication	Autoantibodies against protein disulfide isomerase ER-60 are a diagnostic marker for low-grade testicular inflammation.	25205753
Azoospermia, Orchitis	Altered Intercellular Communication	In sera from infertile azoospermic patients with histologically confirmed low-grade testicular inflammation, significantly elevated titers of autoantibodies against disulfide isomerase family A, member 3 (ER-60) were found.	25205753
Communicable Diseases, Inflammation	Altered Intercellular Communication	Infection and inflammation of the genital tract are supposed to be responsible for up to 15% of cases among infertile males.	25205753
Orchitis	Altered Intercellular Communication	Proteins in lysates of normal testicular tissue were separated by high-resolution 2D gel electrophoresis and probed with sera of 13 patients with histologically confirmed chronic testicular inflammation.	25205753
Orchitis	Altered Intercellular Communication	The newly established ELISA detected significantly elevated titers of autoantibodies against ER-60 in the sera from infertile men with histologically confirmed chronic testicular inflammation (median 8.6; P < 0.01) compared with the control groups.	25205753
Inflammation, Acute epididymo-orchitis, Reproductive tract infection	Altered Intercellular Communication	Moreover, elevated levels of anti-ER-60 titers were detected in patients suffering from acute epididymo-orchitis (median 3.3; P < 0.05) as compared with healthy normozoospermic men (median 2.13; P < 0.001), male blood donors with unknown fertility status (median 2.72; P < 0.01), patients with impaired semen quality but no infection/inflammation (median 2.59; P < 0.001) and patients with symptoms of genital tract infections and/or inflammation (median 2.18; P < 0.001).	25205753
Orchitis	Altered Intercellular Communication	Significantly lower levels of anti-ER-60 antibodies were measured in sera from patients after application of anti-inflammatory pharmacotherapy (median 1.9; P < 0.01) compared with those with histologically confirmed chronic testicular inflammation.	25205753
Orchitis	Altered Intercellular Communication	Measurement of ER-60 autoantibody titers in serum could be a novel non-invasive marker for the diagnosis of asymptomatic testicular inflammation causing male fertility disturbances.	25205753
Infertility, Communicable Diseases, Inflammation	Altered Intercellular Communication	and A.M. are supported by the LOEWE focus group 'MIBIE' (Male infertility during infection and inflammation).	25205753
Inflammation, Cervical lymphadenopathy, Lymphadenopathy, Dirty Bombs, Sinus histiocytosis	Altered Intercellular Communication	Sinus histiocytosis with massive lymphadenopathy (also known as Rosai-Dorfman disease [RDD]) is a benign but chronic cervical lymphadenopathy associated with systemic inflammation.	25207593
Cocaine Abuse, Dacryoadenitis	Altered Intercellular Communication	A 45-year-old female patient with a long history of cocaine abuse presented with bilateral bacterial dacryoadenitis and upper lid inflammation with purulent discharge from a palpebral wound of the right upper lid.	25208047
Gastrointestinal inflammation	Altered Intercellular Communication	Our data suggest that during intestinal inflammation, the TNF-a-mediated activation of IRF1 is related to the subsequent suppression of OPN expression, further reducing p-AKT, p-P38, and p-ERK activities and resulting in aggravation of the injury to intestinal epithelial cells.	25208103
Inflammation	Altered Intercellular Communication	Cystic dilatation within the lacrimal gland is thought to be related to chronic inflammation and scarring of the lacrimal gland ductules.	25208223
Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	Following a baseline examination for plaque, gingival inflammation and bleeding, 75 qualified healthy adult males and females, ages 18-70 were selected to participate in the study.	25208366
Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	The results showed statistically significant reductions in plaque index, gingival inflammation and bleeding on probing.	25208366
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is associated with eosinophilic airway inflammation in 10-20% of patients.	25208464
Tyrosine Transaminase Deficiency Disease, Adrenal cortical hypofunction	Altered Intercellular Communication	This remarkable sign is easily checked, and should prompt a higher index of suspicion towards adrenal insufficiency and other hormonal deficiencies.	25209544
Pituitary Adenoma	Altered Intercellular Communication	However, hormonal changes or the association of PTA with other sellar lesions, such as pituitary adenomas, are extremely rare.	25211451
Inflammation, Urolithiasis, Chronic pyelonephritis	Altered Intercellular Communication	108 patients (89 women and 19 men) aged from 18 to 59 years with chronic pyelonephritis (CP) on the background of urolithiasis in a phase of active inflammation were evaluated.	25211919
Celiac Disease, Inflammation, Autoimmune Diseases	Altered Intercellular Communication	Coeliac disease is an autoimmune disease characterized by inflammation localized to the small bowel, but less is known about systemic signs of inflammation.	25212572
Celiac Disease, Inflammation	Altered Intercellular Communication	A prolonged systemic inflammation may, in turn, contribute to long-term complications known to be associated with untreated coeliac disease.	25212572
Necrotizing granulomatous inflammation	Altered Intercellular Communication	A biopsy was taken and it showed transmural granulomatous inflammation.	25213739
Inflammation, Retinitis Pigmentosa, polychondritis	Altered Intercellular Communication	Relapsing polychondritis (RP) is a rare multisystem disease characterised by progressive inflammation and destruction of cartilaginous structures.	25213785
Inflammation	Altered Intercellular Communication	Age-related macular degeneration in the aspect of chronic low-grade inflammation (pathophysiological parainflammation).	25214719
methyldopa, Inflammation	Altered Intercellular Communication	The products of oxidative stress trigger chronic low-grade inflammation (pathophysiological parainflammation) process in AMD patients.	25214719
methyldopa, Drusen, Inflammation	Altered Intercellular Communication	In early AMD, soft drusen contain many mediators of chronic low-grade inflammation such as C-reactive protein, adducts of the carboxyethylpyrrole protein, immunoglobulins, and acute phase molecules, as well as the complement-related proteins C3a, C5a, C5, C5b-9, CFH, CD35, and CD46.	25214719
methyldopa, Inflammation, Dryness (characteristic)	Altered Intercellular Communication	The complement system, mainly alternative pathway, mediates chronic autologous pathophysiological parainflammation in dry and exudative AMD, especially in the Y402H gene polymorphism, which causes hypofunction/lack of the protective complement factor H (CFH) and facilitates chronic inflammation mediated by C-reactive protein (CRP).	25214719
methyldopa, Immune-mediated	Altered Intercellular Communication	Many autoantibodies (antibodies against alpha beta crystallin, alpha-actinin, amyloid, C1q, chondroitin, collagen I, collagen III, collagen IV, elastin, fibronectin, heparan sulfate, histone H2A, histone H2B, hyaluronic acid, laminin, proteoglycan, vimentin, vitronectin, and aldolase C and pyruvate kinase M2) and overexpression of Fcc receptors play role in immune-mediated inflammation in AMD patients and in animal model.	25214719
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Joint calcium-vitamin D supplementation might improve systemic inflammation through decreasing IL-6 and TNF-a concentrations in vitamin D-insufficient people with type 2 diabetes.	25215557
Inflammation, Vasculitis of large artery, Structure of vasa vasorum	Altered Intercellular Communication	On the basis of the localization of the inflammation, positive TABs were further classified into 4 categories: small vessel vasculitis (SVV), in which inflammation was limited to small periadventitial vessels devoid of muscular coat, with sparing of the temporal artery (32 cases, 9% of the positive biopsies); vasa vasorum vasculitis (VVV), in which inflammation was limited to the adventitial vasa vasorum (23 cases, 6.5% of the positive biopsies); inflammation limited to adventitia (ILA), in which inflammation extended from a strictly perivascular localization to the surrounding adventitia, without medial involvement (25 cases, 7% of the positive biopsies); and transmural inflammation (TMI), in which inflammation crossed the external elastic lamina and extended to the media (274 cases, 77.5% of the positive biopsies).	25216320
Malignant Neoplasms	Altered Intercellular Communication	The Glasgow Prognostic Score (GPS), an inflammation-based score, has been used to predict the biologic behavior of malignant tumors.	25216413
Cholecystitis, Fibrosis Assessment, Inflammation, Chronic cholecystitis	Altered Intercellular Communication	Xanthogranulomatous cholecystitis is a rare variant of chronic cholecystitis characterized by severe proliferative fibrosis and accumulation of lipid-laden macrophages in regions of destructive inflammation.	25216427
Inflammation	Altered Intercellular Communication	High serum concentrations of cortisol were associated with a state of inflammation and independently identified a subgroup of chronic hemodialysis patients at a high mortality risk.	25216457
Demyelination, Meningitis, Encephalomyelitis, Acute Disseminated	Altered Intercellular Communication	Meningeal inflammation and demyelination in a patient clinically diagnosed with acute disseminated encephalomyelitis.	25216555
Airway structure, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	Comprehensive studies of the pathophysiologic characteristics of elderly asthma, including predominant site of disease, airway inflammation profiles, and airway hyperresponsiveness, are scarce despite their clinical importance.	25216975
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	8/9 had non specific upper gastrointestinal symptoms and 3/9 had rectocolic inflammation evoking inflammatory bowel disease.	25217048
palladium, Inflammation, Peritonitis	Altered Intercellular Communication	As PD CA125 increases during peritoneal inflammation, we wished to determine whether measuring PD CA125 during peritonitis provided additional information in determining outcome of peritonitis.	25217152
Inflammation	Altered Intercellular Communication	Aging delays resolution of acute inflammation in mice: reprogramming the host response with novel nano-proresolving medicines.	25217168
Inflammation	Altered Intercellular Communication	Specialized proresolving lipid mediators (SPMs) are endogenous autacoids that actively promote resolution of inflammation.	25217168
Inflammation	Altered Intercellular Communication	In this study, we investigated resolution of acute inflammation in aging and the roles of SPMs.	25217168
Inflammation	Altered Intercellular Communication	These findings provide evidence for age-dependent resolution pathways in acute inflammation and novel means to activate resolution.	25217168
Inflammation, Ear Inflammation	Altered Intercellular Communication	Staged CI was performed in 6 ears, after radical mastoidectomy with closure of the EAC in 3 ears and after intact canal wall mastoidectomy in 3 ears, due to active inflammation or complications related to otitis media.	25217370
Airway structure	Altered Intercellular Communication	Airway inflammation and plasma fibrinogen, but not C-reactive protein, were greater in samples with PPM detection (p < 0.001, p = 0.049 and p = 0.261, respectively).	25218165
Inflammation	Altered Intercellular Communication	Increasing total bacterial load was associated with increasing airway (p < 0.01) but not systemic inflammation (p > 0.05).	25218165
Airway structure	Altered Intercellular Communication	Samples with high total bacterial loads had significantly higher airway inflammation than both samples without PPM detection and those with lower loads.	25218165
ARCN1 gene, Inflammation	Altered Intercellular Communication	Airway and systemic inflammation, as measured by fibrinogen, is greater in stable COPD patients with PPMs detected using the culture-independent qPCR technique.	25218165
Discordance, Inflammation	Altered Intercellular Communication	However, discordance between inflammation and health status was observed.	25218165
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Recent evidence indicates that inflammation is an essential component of pathogenesis and progression of cancer.	25218270
Inflammation, Malnutrition	Altered Intercellular Communication	Periodontal status, inflammation, and malnutrition in hemodialysis patients - is there a link?	25218877
Inflammation, Malnutrition, HD Term Type, Periodontal Diseases, Pervasive Development Disorder	Altered Intercellular Communication	Periodontal disease (PDD) was associated with inflammation, malnutrition, and higher mortality in hemodialysis (HD) patients.	25218877
Inflammation, Malnutrition, Pervasive Development Disorder	Altered Intercellular Communication	Patients with PDD were older; higher percentages of them were smokers, diabetics, had malnutrition, and inflammation.	25218877
Inflammation, Pervasive Development Disorder, Anemia	Altered Intercellular Communication	The prevalence is higher in malnourished and in inflamed patients; inflammation seems to accompany PDD and to influence anemia response to treatment.	25218877
Inflammation, Obesity	Altered Intercellular Communication	Obesity in adolescents from urban and rural areas--a comparison of physical fitness and markers of inflammation.	25219832
Inflammation, Obesity	Altered Intercellular Communication	Obesity entails serious health consequences associated with the development of inflammation in the body and it has an impact on physical fitness.	25219832
Inflammation, Obesity	Altered Intercellular Communication	Obesity is not only related to the development of inflammation in the body, but it is a condition involving the production of proinflammatory cytokines.	25219832
Inflammation, Overweight, Obesity	Altered Intercellular Communication	The study demonstrated inferior results of fitness tests and the presence of features of inflammation in adolescents in both age groups, compared with their peers who had no problems with overweight or obesity.	25219832
Inflammation, Obesity	Altered Intercellular Communication	Young people from rural areas are more at risk of metabolic consequences of obesity than their peers from urban areas, due to poorer fitness and already visible markers of inflammation.	25219832
Inflammation, Gingiva, Periodontal Diseases	Altered Intercellular Communication	Additionally, previous evidence indicates that GroEL from P. gingivalis may possess biological activities involved in systemic inflammation, especially inflammation involved in the progression of periodontal diseases.	25220060
Neoplasms, Ulceration, CTCAE, Catheter-Related Inflammation	Altered Intercellular Communication	Infiltration of tumors with greater number of macrophages and gene expression pathways associated with wound healing and up-regulation of pro-inflammatory cytokines suggests that ulceration is associated with tumor-related inflammation.	25220403
Inflammation, Neoplasms	Altered Intercellular Communication	The relative benefit from interferon reported in patients with ulcerated tumors may reflect modification of signaling pathways involved in inflammation.	25220403
Inflammation, Osage language, Atherosclerosis, Endothelial dysfunction, Sleep Apnea, Obstructive, Hypertension, CTCAE	Altered Intercellular Communication	Accumulated evidence implicates sympathetic activation as inducing oxidative stress and systemic inflammation, which in turn lead to hypertension, endothelial dysfunction, and atherosclerosis in obstructive sleep apnea (OSA).	25221387
Inflammation, Osage language	Altered Intercellular Communication	Statins through their pleiotropic properties may modify inflammation, lipid profile, and cardiovascular outcomes in OSA.	25221387
Inflammation, Pouchitis, Ulcerative Colitis	Altered Intercellular Communication	Of patients with UC, one group (n = 5) was followed longitudinally over the first year after ileostomy closure, another group had pouchitis (n = 15), and another group no inflammation (n = 18).	25222658
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Abnormalities were found in TJP expression in the pouch of patients with UC, in particular, increased expression of the pore-forming claudin 2 as an early event in the development of pouch inflammation and an aberrant DC phenotype was characterized in the ileal pouch of patients with UC.	25222658
Hyperglycemia, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Diabetes is a metabolic pro-inflammatory disorder characterized by chronic hyperglycaemia and increased levels of circulating cytokines suggesting a causal role for inflammation in its aetiology.	25222779
Communicable Diseases, Schistosoma haematobium, Cystitis	Altered Intercellular Communication	Pathological changes due to infection with Schistosoma haematobium include cytokine-mediated urinary tract inflammation.	25223302
Salmonella enterica subsp. salamae, Communicable Diseases, Cystitis	Altered Intercellular Communication	Urinary IL-6 was positively correlated to and IL-10 was negatively correlated to infection intensity and urinary tract inflammation in S. haematobium-infected children.	25223302
Inflammation, Inflammatory cardiomyopathy, Heart failure	Altered Intercellular Communication	Cardiac inflammation has been suggested to play a critical role in the pathogenesis of inflammatory cardiomyopathy as well as in progressive heart failure (HF).	25223819
Infarction, Coagulative necrosis, Skeletal muscle structure, Inflammation	Altered Intercellular Communication	A muscle biopsy demonstrated coagulation necrosis in the skeletal muscle with inflammation and infarction in the walls of small blood vessels.	25224194
Inflammation, Lower Urinary Tract Symptoms, Obesity	Altered Intercellular Communication	Chronic inflammation and obesity may contribute to the genesis or progression of BPH and BPH-associated lower urinary tract symptoms (LUTS).	25224558
Communicable Diseases, Inflammation	Altered Intercellular Communication	A (99m)Tc-labeled antigranulocyte antibody scintigraphy was negative for infection or inflammation.	25224667
Communicable Diseases, Inflammation	Altered Intercellular Communication	This should be considered in patients with such bone replacement materials that are increasingly used, in order to avoid false diagnosis of inflammation or infection.	25224667
Waldenstrom Macroglobulinemia, Portal inflammation, Autoimmune Chronic Hepatitis	Altered Intercellular Communication	Liver biopsies showed a pattern compatible with drug-induced autoimmune hepatitis, featured by severe portal inflammation and lymphoplasmacytic infiltrate.	25224696
Drug-Induced Liver Disease, Inflammation, Autoimmune Chronic Hepatitis, Necrosis	Altered Intercellular Communication	Severe portal inflammation, prominent portal-plasma cells, rosette formation and severe focal necrosis were significantly more frequent in drug-induced autoimmune hepatitis as compared to drug-induced liver injury.	25224696
Behavioral and psychological symptoms of dementia, Neurogenic Inflammation, Data types - Address	Altered Intercellular Communication	The findings indicate a relationship between neuroinflammation and neuropsychiatric symptoms in AD in which anti-inflammatory signalling by IL-10 is beneficial from a mental health perspective.	25224917
Hemangioma, Cavernous, Sarcoidosis, Squamous cell carcinoma, Lymphoma, Fibrous, Orbital Pseudotumor, Central neuroblastoma	Altered Intercellular Communication	Final diagnosis included lymphoma (3), squamous cell carcinoma (1), neuroblastoma (1), amyloid (1), fibrous tissue (1), sarcoidosis (1), cavernous hemangioma (1), and idiopathic orbital inflammation (1).	25226099
Osteomyelitis, Inflammation, Communicable Diseases	Altered Intercellular Communication	Osteomyelitis is an inflammation of the bone caused by an infection.	25226718
Asthma, allergic inflammation	Altered Intercellular Communication	Novel immune-regulatory mechanisms in childhood asthma identified increased Treg cells in patients with AA compared with those in HCs but not those in NA and decreased innate immunity genes for patients with AA, the first potentially indicating a counterregulatory mechanism to suppress cytokines yet not sufficient to control allergic inflammation.	25226851
Inflammation	Altered Intercellular Communication	Very distinctly, patients with NA showed an IL-17-shifted proinflammatory immunity, promoting neutrophil inflammation and less functional Treg cells.	25226851
Specimen Source Codes - Abscess, Meningitis, Cellulitis	Altered Intercellular Communication	We discuss the case of a 33-year-old woman who presented to our emergency department with the signs and symptoms of meningeal inflammation after being prescribed TMP/SMX 3 days earlier for an abscess with cellulitis.	25227653
Ascus (fungus), Postcoital bleeding, Uterine Cervicitis	Altered Intercellular Communication	Colposcopy indications were ASCUS and higher lesions at cervical smear, macroscopic suspicious lesions, post-coital bleeding history with suspicious smear, and repeated cervical inflammation.	25227835
Inflammation	Altered Intercellular Communication	The most common colposcopy indication was ASCUS, and the most common biopsy result was inflammation.	25227835
Inflammation	Altered Intercellular Communication	Sirtuin 1 (SIRT1) is a class III histone deacetylase that may play a critical role in several biological functions, including lifespan, stress, and inflammation.	25228047
Inflammation, Osteoporosis	Altered Intercellular Communication	The potential role of inflammation in bone resorption in patients with osteoporosis was also studied.	25228047
Psoriasis, Metabolic Syndrome X, Hidradenitis Suppurativa, ETV3 wt Allele, Rheumatoid Arthritis, Dermatitis, Chronic inflammatory disorder	Altered Intercellular Communication	IMPORTANCE An association between the metabolic syndrome (MetS) and chronic inflammatory diseases, such as psoriasis or rheumatoid arthritis, has been suggested.Hidradenitis suppurativa (HS), a more localized chronic inflammation of the skin, has been speculated to have a similar association.	25229996
Inflammation, Demyelinating Diseases	Altered Intercellular Communication	Inflammation was greater in the demyelinating diseases compared to non-neurologic controls.	25230202
Inflammation, Demyelination	Altered Intercellular Communication	Olfactory bulb/tract axonal loss was most severe in MS where it correlated significantly with the extent of demyelination (r = 0.610, P = 0.009) and parenchymal inflammation (r = 0.681, P = 0.003).	25230202
Inflammation, Tissue damage, glycation, Hyperglycemia, Infection, Diabetes Mellitus, Chronic disease, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Hyperglycemia induces tissue damage and complications by mechanisms that produce advanced glycation end-products (AGEs) and inflammation.To investigate the factors associated with the progression of complications in Type 2 diabetes patients.We recruited 157 patients (110 women and 47 men) with diabetes for more than 5 years who were non-smokers and did not have current infections or chronic diseases.	25230243
Inflammation, Brain Damage, Chronic, Kidney Diseases, Cardiovascular system	Altered Intercellular Communication	While chronic renal damage is a condition with low-grade inflammation, the potential role of inflammation in kidney disease as a marker of cardiovascular damage is of current interest.	25230678
Renal Insufficiency, Inflammation, Electrocardiogram: myocardial infarction (finding), Coronary Arteriosclerosis	Altered Intercellular Communication	This study analyzed the relationship between renal dysfunction, chronic inflammation, and extension of coronary atherosclerosis in patients with non-ST-segment elevation myocardial infarction (NSTEMI).	25230678
Inflammation, Obesity	Altered Intercellular Communication	Metabolic phenotypes of obesity influence triglyceride and inflammation homoeostasis.	25231836
TG gene, Inflammation, Obesity	Altered Intercellular Communication	Our findings showed that certain types of the metabolic phenotypes of obesity are more favourable modulating phenotypic flexibility after a dynamic fat load test, through TG metabolism and inflammation homoeostasis.	25231836
Inflammation, Crypt hyperplasia, Villous atrophy	Altered Intercellular Communication	In a significant proportion of the remaining study subjects, duodenal biopsy showed villous atrophy, crypt hyperplasia, and lamina propria inflammation, not accompanied by raised intraepithelial lymphocytes (IELs); this was seen more commonly in cases as compared to controls.	25231910
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	In addition to inflammation, coagulation is also induced in vital wounds.	25233021
Inflammation, Lymphohistiocytosis, Hemophagocytic	Altered Intercellular Communication	Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition of uncontrolled immune activation leading to extreme inflammation.	25233452
Inflammation, Chronic granulomatous disease, Actinomycosis, Communicable Diseases, Abscess	Altered Intercellular Communication	Actinomycosis is an uncommon chronic granulomatous infection first described by Bollinger in 1 877.The infection is caused by actinomyces species and it is characterized by slow contiguous spread and suppurative inflammation, formation of multiple abscesses and sinus tracts with possible drainage of "sulfur granules".	25233694
Inflammation	Altered Intercellular Communication	It is characterized by diffuse granulomatous inflammation involving various organs including eye.	25233979
Airway structure	Altered Intercellular Communication	The measurement of the peak exhaled breath temperature (EBT) during multiple tidal breaths offers an easy, non-invasive tool for monitoring airway inflammation.	25234010
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is linked to airway inflammation, which is further aggravated by exacerbations of the disease.	25234010
ARCN1 gene, Airway structure	Altered Intercellular Communication	The peak exhaled breath temperature, recorded during multiple tidal breaths, increases with an acute exacerbation of COPD, and may be related to accelerated airway inflammation.	25234010
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Increased neutrophil-to-lymphocyte ratio (NLR), an index of systemic inflammation, is associated with poor outcome for various types of cancers.	25234022
Carcinogenic Chlorinated Hydrocarbon, HD Term Type, Inflammation	Altered Intercellular Communication	CHC in HD patients was significantly milder according to stage (P = 0.033), grade and its parameters (periportal activity, portal inflammation and lobular activity) (P < 0.001).	25234282
Communicable Diseases, Inflammation, Irritation - emotion, Malignant Neoplasms	Altered Intercellular Communication	Inflammation is a critical component of tumorigenesis, and many cancers arise from sites of infection, chronic irritation, and inflammation.	25234356
Inflammation, Atherosclerosis	Altered Intercellular Communication	Coronary endothelial dysfunction is associated with inflammation and vasa vasorum proliferation in patients with early atherosclerosis.	25234815
Inflammation, Dental Plaque	Altered Intercellular Communication	Inflammation and vasa vasorum play a pivotal role in the pathophysiology of plaque initiation, development, and complications.	25234815
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	The current study further supports the role of inflammation and vasa vasorum proliferation in the early stage of coronary atherosclerosis.	25234815
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The septal inflammation and fibrosis and airspace organization observed in the first biopsies were replaced by less cellular subpleural fibroelastosis within 3-12 years.	25234959
Acute Lung Injury, Interstitial inflammation	Altered Intercellular Communication	Interstitial inflammation or acute lung injury may be an initial step in the development of PPFE.	25234959
Pleurisy, Mesothelial hyperplasia, Malignant Pleural Mesothelioma	Altered Intercellular Communication	Analysis of microRNA expression signatures in malignant pleural mesothelioma, pleural inflammation, and atypical mesothelial hyperplasia reveals common predictive tumorigenesis-related targets.	25236577
Malignant Pleural Mesothelioma, Pleurisy, Pancreatic Polypeptide, Mesothelial hyperplasia, 1-methyl-1-piperidinomethane sulfonate	Altered Intercellular Communication	Pleural chronic inflammation (PP) and mesothelial hyperplasia (HP) may be critical to the development of malignant pleural mesothelioma (MPM).	25236577
Inflammation, square decimeter, Obesity	Altered Intercellular Communication	Chronic inflammation is linked to disorders of obesity, insulin resistance and DM2.	25236830
Inflammation, Peripheral Arterial Diseases	Altered Intercellular Communication	Step-monitored home exercise improves ambulation, vascular function, and inflammation in symptomatic patients with peripheral artery disease: a randomized controlled trial.	25237048
Inflammation, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	This study investigated morning levels of pentraxin3 (PTX3) as a sensitive biomarker for acute inflammation in patients with obstructive sleep apnea (OSA).	25237185
Acute inflammation, Osage language	Altered Intercellular Communication	Based on these results, morning PTX3 levels reflect OSA-related acute inflammation and are a useful marker for improvement in OSA following CPAP therapy.	25237185
Inflammation, Hemorrhage, Calculi, Dental Plaque	Altered Intercellular Communication	Outcome measures were: implant survival; radiographic bone changes; plaque accumulation; bleeding tendency; peri-implant inflammation; presence of dental calculus; biological and technical complications; and patients' satisfaction.	25237669
Communicable Diseases, Atherosclerosis, Inflammatory disorder, Cerebrovascular accident	Altered Intercellular Communication	CCL11 (Eotaxin-1) is an important inflammatory cytokine belonging to the CC family of chemokines associated with a number of infection or inflammation-related diseases such as atherosclerosis and stroke.	25237944
Pain Distress Question, Inflammation	Altered Intercellular Communication	Reduction in Pain and Inflammation Associated With Chronic Low Back Pain With the Use of the Medical Food Theramine.	25237981
Chronic back pain, Inflammation, Back Pain	Altered Intercellular Communication	Treatment with amino acid precursors was associated with substantial improvement in chronic back pain, reduction in inflammation, and improvement in back pain correlated with increased amino acid precursors to neurotransmitters in blood.	25237981
Neurotransmitters	Altered Intercellular Communication	Neurotransmitter deficiency may be related both to increased turnover rate and inadequate neurotransmitter precursors from the diet, particularly for essential and semi-essential amino acids.	25237981
Chronic back pain, Inflammation, Back Pain	Altered Intercellular Communication	Treatment with amino acid precursors was associated with substantial improvement in chronic back pain, reduction in inflammation, and improvement in back pain correlated with increased amino acid precursors to neurotransmitters in blood.	25237981
Inflammation, Thyroid associated opthalmopathies	Altered Intercellular Communication	Novel thermal imaging analysis technique for detecting inflammation in thyroid eye disease.	25238202
Inflammation, Wells syndrome	Altered Intercellular Communication	Eosinophilic cellulitis is an inflammation of, until now, unknown etiology that was first described by George Wells in 1971.	25238447
Pain Distress Question, Erythema, Inflammation, Tonsillitis	Altered Intercellular Communication	The treatment group had a statistically significant improvement in the following symptoms compared with the placebo group: pain associated with tonsillitis, pain on swallowing, erythema and inflammation of the pharynx, and tonsil size.	25238506
Inflammation, Thickened	Altered Intercellular Communication	The LAD showed significant intimal thickening with strong lymphocytic inflammation at the edge of the thickening.	25239164
Inflammation, Anemia	Altered Intercellular Communication	The role of inflammation, iron, and nutritional status in cancer-related anemia: results of a large, prospective, observational study.	25239265
Multiple Organ Failure, Inflammation, Immune System Diseases	Altered Intercellular Communication	Severe injury initiates an inflammatory response that can perpetuate immunological dysfunction, uncontrolled inflammation, and subsequent multisystem organ failure.	25239329
Inflammation, Pancreatic duct	Altered Intercellular Communication	This association is in part due to inflammation from pancreatic ductal obstruction.	25239347
Inflammation, Pancreatitis, Pancreatic Intraductal Papillary Mucinous Neoplasm, Malignant Neoplasms	Altered Intercellular Communication	We hypothesized that serum pancreatic enzymes, markers of inflammation, are a better predictor of malignancy than pancreatitis in patients with IPMN.	25239347
Ulcer, Inflammation, diabetic	Altered Intercellular Communication	We have previously reported that topically applied propolis reduces inflammation and improves cutaneous ulcer healing in diabetic rodents.	25239451
Airway structure, Asthma, Obesity	Altered Intercellular Communication	Obesity is associated with inflammatory processes, which could influence the airway inflammation that is found in patients with asthma.	25239583
Neurodegenerative Disorders, Impaired cognition, Inflammation, Nerve Degeneration	Altered Intercellular Communication	To address whether underlying neurodegenerative pathology increased susceptibility to acute cognitive change, mice at three stages of neurodegenerative disease progression (ME7 model of neurodegeneration: controls, 12 weeks, and 16 weeks) were assessed for acute cognitive dysfunction upon systemic inflammation induced by bacterial lipopolysaccharide (LPS; 100 mg/kg).	25239680
Inflammation, Hypoglycemia, Adverse event, Diabetes Mellitus	Altered Intercellular Communication	Association between severe hypoglycemia, adverse macrovascular events, and inflammation in the Edinburgh Type 2 Diabetes Study.	25239782
Inflammation, Hypoglycemia, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	To determine whether a history of severe hypoglycemia was associated with an increased risk of subsequent macrovascular events in people with type 2 diabetes and to explore possible mediation of this association by inflammation.	25239782
Refractory anemias, Inflammation	Altered Intercellular Communication	These findings suggest that RDW can be considered as a surrogate marker of inflammation and, consequently, CV risk in RA patients.	25239880
Inflammation, Noncommunicable Diseases, Periodontal Diseases	Altered Intercellular Communication	A high frequency of consumption of added sugars is associated with periodontal disease, independent of traditional risk factors, suggesting that this consumption pattern may contribute to the systemic inflammation observed in periodontal disease and associated noncommunicable diseases.	25240081
Inflammation, Dental Plaque	Altered Intercellular Communication	The incidence of cardiovascular events increases with age and inflammation is generally considered to be the main cause of increased plaque vulnerability.	25240113
Inflammation	Altered Intercellular Communication	However, the relationship between age and plaque inflammation has not yet been fully clarified.	25240113
Inflammation, Dental Plaque	Altered Intercellular Communication	The aim of our study was to determine if age-dependent plaque vulnerability is associated with increased plaque inflammation.	25240113
Inflammation, Dental Plaque	Altered Intercellular Communication	Our data imply that increased plaque vulnerability in the symptomatic elderly patients is associated with increased lipid accumulation and impaired tissue repair, rather than with increased plaque inflammation, compared to younger individuals.	25240113
Inflammation, Depression, CTCAE	Altered Intercellular Communication	At the same time, increased inflammation might be of importance in the pathophysiology of depression and suicide.	25240206
Inflammation, Hepatobiliary Disorder, Fibrosis Assessment, Chronic liver disease	Altered Intercellular Communication	The senescent hepatocyte gene signature included changes in cell cycle regulation, morphology, inflammation, signal transduction, metabolism and stellate cell activation, which alongside impaired synthetic function in senescence in vitro were consistent with manifestations of clinical liver disease, suggesting a close relation between hepatocyte senescence and manifestations of chronic liver disease including fibrosis and impaired synthetic function.	25240687
Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	A wide range of recent studies have detected inflammation as one of the most influent factors in the appearance and spreading of neurodegenerative brain diseases.	25240941
Behavior, Periodicity	Altered Intercellular Communication	Hormonal contraception induces artificial cyclicity, which does not, like natural cyclicity, reflect normal, physiological ovarian behaviour.	25241057
Inflammation, Anastomotic Leak	Altered Intercellular Communication	Accurate prediction of anastomotic leakage after colorectal surgery using plasma markers for intestinal damage and inflammation.	25241234
Inflammation, Damage, Anastomotic Leak	Altered Intercellular Communication	Markers of inflammation and gut damage might be suitable, as these are hallmarks of anastomotic leakage.	25241234
Inflammation, Fibrosis Assessment, GDC Disease Response Terminology	Altered Intercellular Communication	In the second cohort of 37 individuals, the DR and the number of HPCs similarly correlated with fibrosis and inflammation after LT.	25241637
Inflammation, Hemorrhage	Altered Intercellular Communication	An intra-operative cystoscopy revealed a distended bladder showing signs of inflammation with diffuse, widespread bleeding.	25241838
Carcinoma, Carcinoma of lung	Altered Intercellular Communication	Lung cancer is an inflammation-associated epithelial carcinoma.	25242236
Inflammation, Disease	Altered Intercellular Communication	Relationship between low grade systematic inflammation and H. pylori should be investigated to find out new predictors for diseases associated with inflammation.	25243160
Inflammation, Asthma	Altered Intercellular Communication	The effect appears to be associated with non-atopic asthma with general increased systemic inflammation.	25243322
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Oxidative damage and inflammation are both implicated in the genesis of hypertension; however, the mechanisms by which these stimuli promote hypertension are not fully understood.	25244096
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Mechanisms involved in the vicious circle of MetS including inflammation, endothelial vasculature and iron metabolism remain to be elucidated.	25245337
Inflammation, Atherosclerosis	Altered Intercellular Communication	Increased CRP and homocysteine might be a key molecule linking inflammation to oxidative stress in atherosclerosis.	25245648
Inflammation, glycation, Overweight, Obesity, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Impact of glycemic control on advanced glycation and inflammation in overweight and obese patients with type 2 diabetes mellitus.	25246279
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Overweight, Obesity	Altered Intercellular Communication	In this study we tried to investigate the impact of glycemic control on parameters of glycation and inflammation in overweight and obese patients with type 2 diabetes mellitus.	25246279
Inflammation	Altered Intercellular Communication	But inflammation is a contributing factor for development of AVF stenosis.	25246339
Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	Systemic and pulmonary inflammation is independent of skeletal muscle changes in patients with chronic obstructive pulmonary disease.	25246784
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Nutritional depletion is an important manifestation of chronic obstructive pulmonary disease (COPD), which has been related to systemic inflammation.	25246784
Airway structure	Altered Intercellular Communication	It remains unclear to what degree airway inflammation contributes to the presence or progression of nutritional depletion.	25246784
ARCN1 gene, Colonization, Airway structure, Muscular Atrophy, Weight decreased	Altered Intercellular Communication	To determine whether airway inflammation and lung bacterial colonization are related to nutritional status or predict progressive weight loss and muscle atrophy in patients with COPD.	25246784
Airway structure, Colonization	Altered Intercellular Communication	There were no differences in airway inflammation and bacterial colonization in patients with and without nutritional depletion.	25246784
Airway structure, Colonization, Muscular Atrophy, Nutritional	Altered Intercellular Communication	Nutritional depletion and progressive muscle atrophy are not related to airway inflammation or bacterial colonization.	25246784
ARCN1 gene, Muscular Atrophy, Pneumonitis	Altered Intercellular Communication	Overspill of pulmonary inflammation is not a key driver of muscle atrophy in COPD.	25246784
allergic inflammation	Altered Intercellular Communication	The step further to understand the role of cytosolic phospholipase A2 alpha and group X secretory phospholipase A2 in allergic inflammation: pilot study.	25247183
Airway structure, Exacerbation of asthma, Bacterial Infections	Altered Intercellular Communication	Allergens, viral, and bacterial infections are responsible for asthma exacerbations that occur with progression of airway inflammation.	25247183
Airway structure	Altered Intercellular Communication	cPLA2 a and sPLA2X are responsible for delivery of arachidonic acid for production of eicosanoids-one of the key mediators of airway inflammation.	25247183
allergic inflammation	Altered Intercellular Communication	However, cPLA2 a and sPLA2X role in allergic inflammation has not been fully elucidated.	25247183
allergic inflammation	Altered Intercellular Communication	sPLA2X seems to be one of important PLA2 isoform in allergic inflammation, especially caused by house dust mite allergens.	25247183
Inflammation, Thrombosis	Altered Intercellular Communication	Our aim was to investigate the association of circulating proteins, the biomarkers of inflammation, blood-brain barrier (BBB) dysfunction, and thrombosis with WMH in non-stroke individuals.	25248031
Inflammation	Altered Intercellular Communication	These antibodies might be a novel marker of chronic inflammation among CD patients non adhering to GFD.	25248239
Inflammation	Altered Intercellular Communication	Based on this characteristic appearance, we diagnosed esophageal intramural pseudodiverticulosis and inflammation of a narrow segment of the esophagus.	25248429
Inflammation, Obesity	Altered Intercellular Communication	Epidemiologic studies examining circulating levels of inflammatory markers in relation to obesity and physical inactivity may aid in our understanding of the role of inflammation in obesity-related cancers.	25249326
Inflammation, Anxiety, CTCAE 3.0	Altered Intercellular Communication	Recently, associations between inflammation and anxiety were identified.	25249351
Juvenile arthritis, Arthritis, Juvenile rheumatoid arthritis	Altered Intercellular Communication	Juvenile Idiopathic Arthritis (JIA) is the most common cause of non-infectious joint inflammation in children.	25249820
Inflammation, Swelling, Pain Distress Question	Altered Intercellular Communication	Synovial inflammation results in pain, swelling and stiffness.	25249820
Inflammation, Pain Distress Question	Altered Intercellular Communication	Animal and adult human studies indicate that localized joint-associated inflammation may produce generalized changes in pain sensitivity.	25249820
Juvenile arthritis, Inflammation	Altered Intercellular Communication	QST data collected from joints were compared within JIA patients: active vs. inactive inflammation; and data from the contralateral thenar eminence were compared between JIA and healthy control cohorts in Europe [EU, (n = 151)] and the US (n = 92).	25249820
Intestinal metaplasia of gastric mucosa, Epithelial hyperplasia, Dysplasia, Inflammation, Primary malignant neoplasm, Exophytic Polypoid Lesion	Altered Intercellular Communication	Age, gender, histopathological wall thickness of gallbladder, reporting rates of acute inflammation, cholesterolosis, polypoid lesions, epithelial hyperplasia, gastric or intestinal metaplasia, dysplasia and incidental cancer were investigated and compared between patients with and without cholesterolosis.	25250528
Polyp of gallbladder, Inflammation, Epithelial hyperplasia	Altered Intercellular Communication	Reported histopathological findings were presented as acute inflammation in 46 (10.7%), cholesterolosis in 79 (18.4%), gallbladder polypoid lesions in 7 (1.6%), epithelial hyperplasia in 16 (3.7%), metaplasia of any type in 34 (7.9%) of 429 patients.	25250528
Wounds and Injuries	Altered Intercellular Communication	Life-threatening traumatic injuries lead to a complex inflammation-driven pathophysiology.	25250597
Inflammation, Disorder of skeletal system	Altered Intercellular Communication	To assess markers of inflammation and bone turnover at presentation and at resolution of Charcot osteoarthropathy.	25251588
Limbic Encephalitis, Inflammation	Altered Intercellular Communication	Limbic encephalitis (LE) is an inflammation of structures of limbic system.	25253433
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Hyperlipidemia	Altered Intercellular Communication	Low-grade inflammation, characterized by increased pro-inflammatory cytokine levels, is present in patients with obesity-linked insulin resistance, hyperglycemia and hyperlipidemia and considered to play a leading role to progression into type 2 diabetes (T2D).	25254631
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	In adipose tissue in obese patients and in pancreatic islets in T2D patients cellular inflammation is present.	25254631
Gastroesophageal reflux disease, Inflammation, Bipolar Disorder	Altered Intercellular Communication	Studies have shown that chronic inflammation may play a vital role in the pathophysiology of both gastroesophageal reflux disease (GERD) and bipolar disorder.	25255080
ARCN1 gene, Aneurysm, Inflammation, Arterial Occlusive Diseases	Altered Intercellular Communication	Here we show that COPD is significantly more prevalent in aneurysm patients compared to arterial occlusive disease patients, independent of smoking, other clinical risk factors and inflammation.	25255451
ARCN1 gene, Inflammation, Aneurysm	Altered Intercellular Communication	Our experimental data identify genetic susceptibility to extracellular matrix degradation and secondary inflammation as the common mechanisms in both COPD and aneurysm formation.	25255451
Small cell carcinoma of lung	Altered Intercellular Communication	A systemic inflammation-based prognostic scores (mGPS) predicts overall survival of patients with small-cell lung cancer.	25256672
Inflammation, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Biopsies were systematically reviewed for inflammation, fibrosis and the presence of interface hepatitis, plasma cells, rosettes and emperipolesis with a well-defined assessment method.	25257662
Infarction, Inflammation	Altered Intercellular Communication	Downregulation of serum brain specific microRNA is associated with inflammation and infarct volume in acute ischemic stroke.	25257664
Inflammation, Hyperreactivity, Chronic inflammatory disorder	Altered Intercellular Communication	Asthma is a highly prevalent chronic inflammatory disease characterised by reversible airflow obstruction and hyperreactivity and inflammation of the airways.	25258133
Inflammation, Parkinson Disease, Presenile dementia, Coronary heart disease, Cerebrovascular accident, Diabetes Mellitus, Depression, CTCAE, Hypertension, CTCAE	Altered Intercellular Communication	In depression patients who do not exhibit risk factors, including hypertension, diabetes, coronary heart disease, stroke, Parkinson's disease and dementia, particularly in young people, inflammation is a likely risk factor for depression.	25258357
Depression, CTCAE	Altered Intercellular Communication	Inflammatory processes, which provoke alternations of neurotransmitter metabolism, neuroendocrine function, and neuroplasticity in the brain, might promote depression.	25258357
Pain Distress Question, Inflammation, Retinal Detachment, Secondary Infections, Endophthalmitis, CTCAE, Conjunctival hemorrhage	Altered Intercellular Communication	Other adverse events, such as conjunctival hemorrhage, eye pain, secondary infection, endophthalmitis, noninfectious inflammation, retinal detachment, and implant migration, were also recorded during follow-up.	25258512
Inflammation	Altered Intercellular Communication	Topical ketorolac may reduce the inflammation caused by photocoagulation and improve visual outcome.	25259426
Inflammation, Retinal damage	Altered Intercellular Communication	It is characterized by intraocular neovascularization, inflammation and retinal damage which can be ameliorated through intraocular injections of glucocorticoids.	25259682
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	There is evidence that chronic inflammation is associated with the progression/development of chronic renal failure; however, relations in subjects with preserved renal function remain insufficiently understood.	25259714
Inflammation, Kidney Failure	Altered Intercellular Communication	To examine the association of inflammation with the development of renal failure in a cohort of the elderly general population.	25259714
Inflammation, Overhydration	Altered Intercellular Communication	Study on overhydration in dialysis patients and its association with inflammation.	25259812
HD Term Type, Chronic Kidney Diseases	Altered Intercellular Communication	Patients with chronic kidney disease receiving haemodialysis (HD) have permanent variations in hydration status that may affect their survival. To analyse hydration status and body composition in patients on haemodialysis and its relation to inflammation. We included 128 prevalent clinically stable patients on haemodialysis.	25259812
Granulomatous inflammation, Scedosporium apiospermum	Altered Intercellular Communication	The biopsy revealed granulomatous inflammation with numerous fungal hyphae, which were IDentified as Scedosporium apiospermum by PCR.	25260303
Sepsis, Inflammation, Liver damage	Altered Intercellular Communication	Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation.	25260379
Inflammation, Liver damage, septic	Altered Intercellular Communication	Histone levels in septic patients are significantly increased and might mediate disease aggravation by cellular injury and inflammation via TLR4 signaling, which potentially results in multiple organ failure and fatal outcome.	25260379
Inflammation	Altered Intercellular Communication	Elaboration is also needed on the mechanisms by which social disadvantage may cause chronic inflammation.	25260501
Inflammation	Altered Intercellular Communication	Inflammation, including complement activation, plays an important role in tumorigenesis.	25261356
Communicable Diseases, Inflammation	Altered Intercellular Communication	IL-17A is a proinflammatory cytokine, which modulates immune cell trafficking and is involved inflammation in (auto)immune and infectious diseases.	25261478
Chronic inflammation	Altered Intercellular Communication	The MPO concentration is likely to increase in patients with chronic inflammation.	25261597
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	Here, we determined serum MPO levels in rheumatoid arthritis (RA) and other autoimmune or inflammatory conditions, and investigated the associations between MPO levels and disease activity indicators in RA.	25261597
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	Inflammation plays an important role in gastric cancer (GC) development and progression.	25261987
Per Visual Field, Inflammation, Vessel Failure Indicator	Altered Intercellular Communication	Inflammation plays a key role in the multi-factorial process eventually leading to target vessel failure (TVF) after drug-eluting-stent (DES) implantation.	25262477
Inflammation, Cerebral Hemorrhage	Altered Intercellular Communication	YKL-40 is associated with inflammation and severity of intracerebral hemorrhage, and may independently predict long-term clinical outcomes of intracerebral hemorrhage.	25262987
Skeletal muscle atrophy	Altered Intercellular Communication	The E3 ubiquitin ligase TRIM62 and inflammation-induced skeletal muscle atrophy.	25263070
Inflammation	Altered Intercellular Communication	Inflammation and acute-phase response occur directly within myocytes and contribute to ICUAW.	25263070
Inflammation	Altered Intercellular Communication	We observed that tripartite motif-containing 62 (TRIM62), an E3 ubiquitin ligase and modifier of inflammation, is increased in the skeletal muscle of ICUAW patients.	25263070
Inflammation	Altered Intercellular Communication	It could play a role in the pathogenesis of ICUAW by activating and maintaining inflammation in myocytes.	25263070
Diabetic Nephropathy, Inflammation, Metabolic Diseases, Fibrosis Assessment	Altered Intercellular Communication	Klotho may participate in the development of DKD pathological mechanism such as oxidative stress related to inflammation, renal fibrosis, lipid metabolic disorders, modulating the pathological process of diabetic kidney tissue.	25263500
Orchitis	Altered Intercellular Communication	It was found instead a higher diverticular inflammation degree in patients treated for DD compared with those treated for ADK associated with DD.	25263945
Inflammation, Burn injury	Altered Intercellular Communication	Serum albumin levels correlate with inflammation rather than nutrition supply in burns patients: a retrospective study.	25264055
Inflammation, Burn injury	Altered Intercellular Communication	To clarify whether provision of nutrition or presence of inflammation affects serum albumin levels, we studied serum albumin levels, C-reactive protein (CRP) levels and caloric intake over time in 30 patients with burns.	25264055
Inflammation	Altered Intercellular Communication	Increased permeability and uptake of proinflammatory bacterial endotoxins from gut microbiota has been suggested as a mechanism for obesity-associated chronic inflammation that causes obesity-associated insulin resistance.	25264329
Inflammation	Altered Intercellular Communication	We hypothesized that intestinal barrier function may be restored after Roux-en-Y gastric bypass (RYGB) surgery and thereby contribute to decreased inflammation.	25264329
Inflammation, Toxic effect	Altered Intercellular Communication	No significant difference was reached in toxicity, inflammation, and oxidative stress markers.	25265206
Inflammation	Altered Intercellular Communication	It triggers systemic inflammation, the role of which remains unclear.	25265569
Sepsis, Inflammation	Altered Intercellular Communication	In the current study, we investigated the induction of microRNA (miRNA) during sepsis and their role in the regulation of inflammation.	25265569
Sepsis, Inflammation	Altered Intercellular Communication	The current study demonstrates that miRNA dysregulation correlates with clinical manifestations and inflammation, and therefore remains a potential therapeutic target against sepsis.	25265569
Inflammation, Sarcoidosis	Altered Intercellular Communication	Microscopically, cutaneous sarcoidosis may exhibit a grenz zone and may show perineural inflammation and foreign bodies.	25265873
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Chemokines and their receptors acts as mediators of migration of immune cells to the site of inflammation and deregulated inflammatory response is associated with increased risk of cancer.	25266801
Inflammation, Hypertensive (finding), Hypertension, CTCAE	Altered Intercellular Communication	Associations of daytime, nighttime, and 24-hour heart rate with four distinct markers of inflammation in hypertensive patients: the Styrian Hypertension Study.	25266946
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	The transcription factor NF-kB is indispensable for intestinal immune homeostasis, but contributes to chronic inflammation and inflammatory bowel disease (IBD).	25267258
Esophagitis	Altered Intercellular Communication	The median CReSS total in volunteers (4) was significantly lower (P < .002) than in ear, nose, and throat (ENT) patients (26) or EGD patients with (42) or without (32) esophageal inflammation.	25267601
Acute inflammation	Altered Intercellular Communication	All corneas were clear and only mild postoperative inflammation was observed.	25268083
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	These findings suggest that IL-35 may very probably be involved in the Th2 and Th17 mediated inflammation process of asthma and COPD.	25268338
Airway structure, Asthma	Altered Intercellular Communication	The most important way to achieve and maintain asthma control is to reduce airway inflammation.	25268339
Communicable Diseases, Inflammation, Neoplasms	Altered Intercellular Communication	Thus, the assessment of the HCMV expression in tumours of various origins and pathologically altered tissue in conditions such as inflammation, infection, and even degeneration should certainly be facilitated.	25268364
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Elevations in soluble markers of inflammation and changes in leukocyte subset distribution are frequently reported in patients with coronary artery disease (CAD).	25268632
Infection caused by Helicobacter pylori	Altered Intercellular Communication	It was shown that GM inflammation in patients with DU and BA is associated not only with H. pylori infection but also with the phase of BA.	25269182
Inflammation	Altered Intercellular Communication	Growing density of eosinophil, neutrophil and mast cell infiltration of fundal and antral GM as well as increased total number of cells in the antrum reflects active immune-mediated inflammation in GM lamina propria.	25269182
Inflammation	Altered Intercellular Communication	One of the possible factors determining combination of H. pylori-associated duodenal ulcer with BA is chronic hyperergic inflammation and marked structural changes in GM.	25269182
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	In sarcoidosis, an antigen specific immune response is a putative mechanism, resulting in granulomatous inflammation.	25269709
Airway structure	Altered Intercellular Communication	It increases airway inflammation and influences outcomes negatively.	25269711
Refractory anemias, Inflammation, destruction joint, Rheumatoid Arthritis	Altered Intercellular Communication	Synovial inflammation and joint destruction in rheumatoid arthritis (RA) may progress despite clinical remission.	25270553
Refractory anemias, Inflammation	Altered Intercellular Communication	Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is increasingly used to detect synovial inflammation in RA.	25270553
Inflammation	Altered Intercellular Communication	Perfusion imaging of synovial tissue in RA finger joints employing DCE-MRI reflects histological synovial inflammation.	25270553
Carcinoma, Chronic osteomyelitis	Altered Intercellular Communication	Inflammation- and tumor-free alveolar bone sections from human mandibles (n = 31) with previously diagnosed carcinoma, chronic osteomyelitis or cysts were analyzed histomorphologically and histomorphometrically as to the dimension of trabeculae in cancellous areas.	25271067
Liver carcinoma	Altered Intercellular Communication	Systemic immune-inflammation index predicts prognosis of patients after curative resection for hepatocellular carcinoma.	25271081
Liver carcinoma, FAM126A gene	Altered Intercellular Communication	We developed a novel systemic immune-inflammation index (SII) based on lymphocyte, neutrophil, and platelet counts and explored its prognostic value in hepatocellular carcinoma (HCC).	25271081
Inflammation, Chronic frontal sinusitis, Frontal Sinusitis	Altered Intercellular Communication	The goal of this study was to identify these anatomical factors and inflammation areas relating to chronic frontal sinusitis by comparing radiological presentations in patients with and without frontal sinusitis.	25271525
Chronic frontal sinusitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	It provides evidence that mucosal inflammation disease in these two areas is a very important factor leading to chronic frontal sinusitis.	25271525
Inflammation, Traumatic injury	Altered Intercellular Communication	The molecular dynamics governing immune cell recruitment to sites of injury and disease in the CNS during sterile inflammation remain poorly defined.	25271625
Inflammation, Contracture, Microbial Biofilms	Altered Intercellular Communication	The etiology is uncertain, but bacterial biofilms have been suggested as trigger for chronic peri-implant inflammation, eventually leading to capsular contracture.	25272211
Inflammation, Injury of cardiac valve	Altered Intercellular Communication	We hypothesize that biomarkers for inflammation, neurohumoral activation, and cardiac injury can predict appropriate shocks and all-cause mortality in patients with primary prevention ICDs.	25273351
Cessation of life, Inflammation, Shock, myocardial injury	Altered Intercellular Communication	An increase in serum biomarkers of inflammation, neurohumoral activation, and myocardial injury increased the risk for death but poorly predicted the likelihood of an ICD shock.	25273351
Inflammation, Carotidynia	Altered Intercellular Communication	Carotidynia is characterised by inflammation limited to the common carotid artery, which has been recognised as a distinct disease entity by advanced vascular imaging.	25273942
Inflammation	Altered Intercellular Communication	We report a ventriculo-atrial defect due to a paravalvular aortic prosthetic defect, secondary to inflammation, a novel third type of a Gerbode defect.	25274005
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	YKL-40 is a novel biomarker in diseases with inflammation, fibrosis and tissue remodelling.	25274153
Inflammation, Smoking	Altered Intercellular Communication	Smoking is associated with a broad range of alterations in systemic immune and inflammation marker levels among older, long-term smokers.	25274579
Refractory anemias, Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	To determine whether macrophage targeting by (R)-11C-PK11195 positron emission tomography (PET) can visualize subclinical joint inflammation in patients with rheumatoid arthritis (RA) without clinical arthritis during or after treatment, with flare as clinical outcome measure.	25274888
Rheumatoid Arthritis	Altered Intercellular Communication	Patients with rheumatoid arthritis in clinical remission manifest persistent joint inflammation on histology and imaging studies.	25274900
Refractory anemias, Rheumatoid Arthritis, Inflammation, Synovitis	Altered Intercellular Communication	The purpose of our study was to test the hypothesis that synovitis on magnetic resonance imaging (MRI) and ultrasound (US) observed in patients with rheumatoid arthritis (RA) who meet remission criteria reflects active inflammation on histopathology.	25274900
Inflammation, Hyperplasia	Altered Intercellular Communication	Histological specimens were scored for hyperplasia of synovial lining and synovial stroma, inflammation, lymphoid follicles, and vascularity.	25274900
Stomach Carcinoma	Altered Intercellular Communication	Improvement of high-sensitivity inflammation-based Glasgow prognostic score by gastrectomy is a favorable prognostic factor in patients with gastric cancer.	25275076
Bronchitis	Altered Intercellular Communication	However, little is known about the role of prostacyclin in neutrophilic bronchial inflammation.	25275218
Carcinoma of lung	Altered Intercellular Communication	Prognostic significance of systemic inflammation-based lymphocyte- monocyte ratio in patients with lung cancer: based on a large cohort study.	25275631
Inflammation	Altered Intercellular Communication	The relatively benign-appearing radiograph and biopsy report of chronic inflammation resulted in curettage and nailing of the lesion.	25275985
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Inflammation and growth in young children with obstructive sleep apnea syndrome before and after adenotonsillectomy.	25276051
Inflammation	Altered Intercellular Communication	Our findings imply that systemic inflammation may have an important role in this OSA-related morbidity.	25276051
Inflammation, Chronic disease	Altered Intercellular Communication	The 0.5% Jussara supplementation reverses the adverse effects of perinatal TFAs, improving lipid profiles, glucose levels, body composition, and gut microbiota and reducing low-grade inflammation in the colon of 21-day-old offspring, and could contribute to reducing chronic disease development.	25276060
Alzheimers Disease", Inflammation	Altered Intercellular Communication	In Alzheimer's disease, the contribution of inflammation is still controversially discussed.	25277040
Primary malignant neoplasm, Depression, CTCAE	Altered Intercellular Communication	Cancer patients under maintenance hemodialysis: relationship between quality of life, depression, sleep quality and malnutrition-inflammation score.	25277248
methyldopa, Polypoidal choroidal vasculopathy	Altered Intercellular Communication	To determine the genetic association of an inflammation-related gene, formyl peptide receptor 1 (FPR1), in exudative age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV).	25277308
Inflammation, Hypercholesterolemia	Altered Intercellular Communication	Nonpharmacological lipoprotein apheresis reduces arterial inflammation in familial hypercholesterolemia.	25277610
Arteritis	Altered Intercellular Communication	There was a significant reduction of arterial inflammation after lipoprotein apheresis (TBR: 2.05 +- 0.31 vs. 1.91 +- 0.33; p < 0.02).	25277610
Inflammation, Family history	Altered Intercellular Communication	The arterial wall of FH patients is characterized by increased inflammation, which is markedly reduced after lipoprotein apheresis.	25277610
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Fish oil for the reduction of atrial fibrillation recurrence, inflammation, and oxidative stress.	25277614
Inflammation	Altered Intercellular Communication	Furthermore, fish oil does not reduce inflammation or oxidative stress markers in this population, which may explain its lack of efficacy.	25277614
Inflammation, Demyelination, MS gene, Nerve Degeneration	Altered Intercellular Communication	Oxidative stress induced by lipid peroxidation is related with inflammation of demyelination and neurodegeneration in multiple sclerosis.	25277682
Inflammation	Altered Intercellular Communication	Inflammation can lead to oxidative stress and vice versa.	25277682
Inflammation, Demyelination, MS gene, Nerve Degeneration	Altered Intercellular Communication	Thus, oxidative stress is involved in the inflammation leading demyelination and neurodegeneration in the pathogenesis of multiple sclerosis.	25277682
Inflammation	Altered Intercellular Communication	All underwent abdominal CT which showed ovoid fat inflammation along the course of the perigastric ligaments (gastrohepatic, gastrosplenic, and falciform).	25278036
Inflammation	Altered Intercellular Communication	Although the inflammation was correctly described, the specific diagnosis was not made on initial interpretation in five patients.	25278036
Inflammation	Altered Intercellular Communication	Radiologists should be aware of the entity to avoid unnecessary intervention, and recognize the CT findings of ovoid fat inflammation in the distribution of the perigastric ligaments.	25278036
Inflammation	Altered Intercellular Communication	Dynamic, contrast-enhanced magnetic resonance imaging (DCE MRI) provides quantitative, novel measures of synovial inflammation.	25278070
Inflammation	Altered Intercellular Communication	The association between EER and symptomatic response to IACS may reflect a closer relation of this biomarker to synovial inflammation than with volumetric assessment.	25278070
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The degree to which these features reflect "active inflammation" is questionable and they may be better considered as part of the total organ pathology in OA.	25278071
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Imaging of (peri)articular structures and inflammation with Ultrasonography (US) during the course of osteoarthritis (OA) might contribute to knowledge about early diagnosis of OA, prognosis and possibly the effect of disease modifying drugs.	25278074
Synovial Hypertrophy	Altered Intercellular Communication	Inflammation like effusion and synovial hypertrophy does occur in over 40% of patients at some time in the year of follow up and shows a fluctuating pattern.	25278074
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	MUS examination for knee OA consists of five separate domains assessing (1) predominantly morphological changes in the medial compartment, (2) predominantly inflammation in the medial compartment, (3) predominantly morphological changes in the lateral compartment, (4) predominantly inflammation in the lateral compartment, and (5) effusion.	25278077
Alopecia Areata, Dacryoadenitis	Altered Intercellular Communication	The association of lacrimal gland inflammation with alopecia areata.	25280049
Alopecia Areata, Dacryoadenitis	Altered Intercellular Communication	To describe the association of lacrimal gland inflammation with alopecia areata.	25280049
Alopecia, CTCAE, Dacryoadenitis	Altered Intercellular Communication	We reviewed the medical records of 4 patients diagnosed with lacrimal gland inflammation who had an antecedent or subsequent episode of alopecia.	25280049
Alopecia, CTCAE, LACRIMAL INFLAMMATION	Altered Intercellular Communication	Two developed alopecia after presentation for lacrimal inflammation.	25280049
Alopecia Areata, Dacryoadenitis	Altered Intercellular Communication	Lacrimal gland inflammation and alopecia areata are autoimmune processes that can be seen in association with each other.	25280049
Hypoparathyroidism, Primary Hypoparathyroidism, Hypocalcemia	Altered Intercellular Communication	Primary hypoparathyroidism is a rare condition caused by parathyroid hormone deficiency and characterized by hypocalcemia.	25280468
Abnormal renal function, Inflammation	Altered Intercellular Communication	In the United States population, high dietary fiber intake has been associated with a lower risk of inflammation and mortality in individuals with kidney dysfunction.	25280496
Communicable Diseases, Inflammation, Aspergillus fumigatus allergenic extract	Altered Intercellular Communication	Trans-sphenoidal surgery with biopsy showed inflammation was caused by infection with Aspergillus fumigatus.	25280605
Inflammation, Observation Method - Coagulation, Viremia	Altered Intercellular Communication	Activation, senescence, exhaustion and differentiation stage in CD4+ and CD8+ T lymphocyte subsets, markers of monocyte activation, microbial translocation, inflammation, coagulation and low-level viremia were assessed.	25280865
Inflammation	Altered Intercellular Communication	Monocyte activation was independently associated with markers of inflammation (IL-6, p=0.006), microbial translocation (LBP, p=0.01) and low-level viremia (p=0.01).	25280865
Neurodegenerative Disorders, Abnormality of mitochondrial metabolism, Disturbance	Altered Intercellular Communication	Thus, neurosteroids may act upon neuronal bioenergetics in a delicate balance and an age-related steroid disturbance might be involved in mitochondrial dysfunction underlying neurodegenerative disorders.	25281013
Airway structure, Asthma	Altered Intercellular Communication	Few data are available on the proportion of asthmatics achieving a good asthma control (according GINA guidelines) and on the level of airway inflammation during omalizumab treatment.	25281265
Aggressive course, Malignant neoplasm of endometrium	Altered Intercellular Communication	In endometrial cancer loss of progesterone receptor (PR, gene name PGR) is associated with aggressive disease and altered response to hormonal treatment.	25281525
Inflammation	Altered Intercellular Communication	Compare the efficacy of inhaled budesonide and systemic methylprednisolone on systemic inflammation of AECOPD.	25281894
Inflammation	Altered Intercellular Communication	To compare the efficacy of inhaled budesonide and systemic methylprednisolone on systemic inflammation of AECOPD.	25281894
Inflammation	Altered Intercellular Communication	Inhaled budesonide and systemic methylprednisolone have the same effects on systemic inflammation of AECOPD.	25281894
Inflammation, atherosclerotic, Atherosclerosis	Altered Intercellular Communication	We demonstrated that sRAGE and esRAGE are associated with atherosclerotic risk factors in early-stage atherosclerosis, suggesting that their levels evolve in correlation with those of metabolic components and inflammation.	25282185
Refractory anemias, Inflammation	Altered Intercellular Communication	The S100A12 protein was significantly associated with other inflammatory markers, clinical assessments as well as sum US scores, indicating that S100A12 is a potential marker of inflammation in RA patients.	25282581
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Galectin-3 has been recently recognized as a biomarker of cardiovascular fibrosis and inflammation.	25282685
Inflammation	Altered Intercellular Communication	[Odontogenic inflammations of head and neck area treated in the Department of Otolaryngology in St. Lukasz Regional Hospital - five years observation].	25283320
Inflammation	Altered Intercellular Communication	That's why treatment of odontogenic inflammations is often difficult and prolonged.	25283320
Inflammation	Altered Intercellular Communication	The authors reveal a cost burden in a public health care as a result of odontogenic inflammations.	25283320
Inflammation, Swelling	Altered Intercellular Communication	Three patients with remote filler injection (hyaluronic acid and polyalkylimide), not volunteered on initial history, presented with peri-orbital swelling and/or inflammation that was suspicious in each case for more serious pathology.	25284105
Inflammation, Sarcoidosis, Psoriasis, Chronic inflammatory disorder	Altered Intercellular Communication	Like psoriasis, sarcoidosis is a chronic inflammatory disorder with Th1/Th17-driven inflammation.	25285443
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Chronic inflammation is a key feature of the pathology present in Alzheimer's disease (AD)-affected brains resulting from responses to amyloid plaques or neurofibrillary tangles, the pathological hallmarks of AD.	25286386
Hypernatremia, Inflammation, Fibrosis Assessment, Heart Ventricle	Altered Intercellular Communication	Sex-dependent regulation of fibrosis and inflammation in human left ventricular remodelling under pressure overload.	25287281
Adenocarcinoma, Inflammation, Specimen Source Codes - Abscess	Altered Intercellular Communication	The pathologic report showed severe inflammation with abscess formation and an unexpected adenocarcinoma that appeared to invade the perimuscular connective tissue.	25287623
Inflammation, Macular degeneration	Altered Intercellular Communication	The significant associations of mCNV in highly myopic eyes with elevated levels of vascular endothelial growth factor or inflammatory cytokines and maculopathy lesions strongly suggest an involvement of inflammation in the etiology of mCNVs.	25289657
Inflammation, Non-Small Cell Lung Carcinoma, pulmonary toxicity	Altered Intercellular Communication	Lung inflammation leading to pulmonary toxicity after radiotherapy (RT) can occur in patients with non-small cell lung cancer (NSCLC).	25289758
Toxic effect, Gastrointestinal inflammation, Leukopenia, Maculopapular Lesion, DLST wt Allele	Altered Intercellular Communication	Dose-limiting toxicities (DLTs) for dalotuzumab/MK-2206 included grade 4 neutropenia and grade 3 serum sickness-like reaction, maculopapular rash, and gastrointestinal inflammation.	25290091
Sepsis, Thrombosis of jugular vein, septic	Altered Intercellular Communication	Septic internal jugular vein thrombosis should always be included in the differential diagnosis of local neck inflammation and systemic sepsis in intravenous drug users.	25290582
Malignant tumor of colon, Inflammation, Inflammatory Bowel Diseases, Colitis, Primary sclerosing cholangitis, Colorectal Carcinoma	Altered Intercellular Communication	Colon cancer risk in IBD increases with longer duration and greater anatomic extent of colitis, the presence of primary sclerosing cholangitis, family history of CRC and degree of inflammation of the bowel.	25292045
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Interleukin-12 (IL-12) as an antitumor and interleukin-6 (IL-6) as an inflammatory cytokine, are immunomodulatory products that play important roles in responses in cancers and inflammation.	25292079
Stomach Carcinoma	Altered Intercellular Communication	Prognostic value of preoperative inflammation-based prognostic scores on hospital mortality after gastric cancer surgery.	25292085
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	Previous studies demonstrated relationships between gastric cancer and chronic inflammation.	25292085
Venous Thromboembolism, Cerebrovascular accident	Altered Intercellular Communication	Inflammation markers and incident venous thromboembolism: the REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort.	25292154
Inflammation, Venous Thromboembolism, vinyltriethoxysilane, Obesity	Altered Intercellular Communication	Inflammation biomarkers are associated with the venous thromboembolism (VTE) risk factors obesity and age; however, the relationships of inflammation with VTE risk remain controversial.	25292154
Inflammation, vinyltriethoxysilane, Obesity	Altered Intercellular Communication	These data suggest that inflammation may be a potential mechanism underlying the relationship between obesity and VTE risk.	25292154
Non-alcoholic Fatty Liver Disease, Impaired health	Altered Intercellular Communication	This impairment may affect HSP70-dependent anti-inflammation, with consequent oxidative stress and insulin resistance in advanced stages of NAFLD.	25292174
Prostate carcinoma, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	Prostatic inflammation is of considerable importance to urologic research because of its association with benign prostatic hyperplasia and prostate cancer.	25292180
Inflammation	Altered Intercellular Communication	However, the mechanisms by which inflammation leads to proliferation and growth remain obscure.	25292180
Inflammation, Hyperplasia	Altered Intercellular Communication	Using genetic models and in vivo IGF receptor blockade, we demonstrate that the hyperplastic response to inflammation depends on interleukin-1-driven IGF signaling.	25292180
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	We show that human prostatic hyperplasia is associated with IGF pathway activation specifically localized to foci of inflammation.	25292180
Hyperplasia	Altered Intercellular Communication	This demonstrates that mechanisms of inflammation-induced epithelial proliferation and hyperplasia involve the induction of developmental growth factors, further establishing a link between inflammatory and developmental signals and providing a mechanistic basis for the management of proliferative diseases by IGF pathway modulation.	25292180
Refractory anemias, Inflammation, Damage	Altered Intercellular Communication	Combination of HR-pQCT and MRI modalities may provide powerful tools to evaluate joint inflammation and bone damage in RA.	25293500
Candida albicans, Inflammation, Dental Plaque	Altered Intercellular Communication	In addition, those who wore dentures during sleep were more likely to have tongue and denture plaque, gum inflammation, positive culture for Candida albicans, and higher levels of circulating interleukin-6 as compared with their counterparts.	25294364
Primary malignant neoplasm, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	Hepatocellular carcinoma (HCC) is a prototype of inflammation-associated cancer.	25294684
Hepatocarcinogenesis	Altered Intercellular Communication	The finding of IL-1b/IRAK-1 signaling promoting Gankyrin expression through JNK and NF-Y/p300/CBP complex provides a fresh view on inflammation-enhanced hepatocarcinogenesis.	25294684
Hepatocarcinogenesis	Altered Intercellular Communication	Interleukin-1b/Iinterleukin-1 receptor-associated kinase 1 inflammatory signaling contributes to persistent Gankyrin activation during hepatocarcinogenesis.	25294684
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	DPP4 activity is an important predictor of the onset of inflammation and MAU in Chinese apparently without diabetes.	25294850
ovarian neoplasm, Pelvic Inflammatory Disease, Endometriosis	Altered Intercellular Communication	We performed here a comprehensive immune gene expression analysis of pelvic inflammation in endometriosis and endometriosis-associated ovarian cancer (EAOC).	25294912
Inflammation, Endometriosis	Altered Intercellular Communication	One third of the patients with endometriosis revealed a tumor-like inflammation profile, suggesting that cancer-like immune signatures may develop earlier, in patients classified as clinically benign.	25294912
Inflammation, Endometriosis	Altered Intercellular Communication	These findings reveal new characteristics of inflammation in precursor lesions and point to previously unknown roles of complement in endometriosis and EAOC.	25294912
Inflammatory, Inflammation	Altered Intercellular Communication	Angiopoietin-like protein 2 (ANGPTL2) is a mediator of chronic inflammation and inflammatory carcinogenesis.	25294915
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Leptin, a possible mediator between energy homeostasis, inflammation and cardiovascular disease (CVD), acts via leptin receptors.	25296580
Endocrine System Diseases, Acne, Inflammatory acne	Altered Intercellular Communication	The stereotype of adult female acne being due to hormonal disturbances presenting as inflammatory acne localized only to the mandibular area was not found in the majority of this large group.	25296739
Inflammation, Schistosoma, Colonic Polyps	Altered Intercellular Communication	However, colon polyps associated with Schistosoma in the absence of inflammation have rarely been reported, especially in young people; this is the first case with the following presentation.	25296942
Giant Cell Arteritis, Granulomatous inflammation, GCA gene, Autoimmune Diseases	Altered Intercellular Communication	Giant cell arteritis (GCA) is an autoimmune disease characterized by granulomatous inflammation in the wall of medium-sized and large-sized arteries, and it usually occurs in patients over 50 years of age.	25297504
Inflammation, Bacterial Endocarditis	Altered Intercellular Communication	Inflammation in infective endocarditis (IE) is a complex network including interactions of inflammatory cytokines and other components of host response.	25299518
Inflammation, Alpha one fetoprotein measurement, Myelitis, Acute flaccid paralysis	Altered Intercellular Communication	In August 2012, the California Department of Public Health (CDPH) was contacted by a San Francisco Bay area clinician who requested poliovirus testing for an unvaccinated man aged 29 years with acute flaccid paralysis (AFP) associated with anterior myelitis (i.e., evidence of inflammation of the spinal cord involving the grey matter including anterior horn cell bodies) and no history of international travel during the month before symptom onset.	25299608
Inflammation, Obesity	Altered Intercellular Communication	Human SC WAT increases thermogenic genes seasonally and acutely in response to a cold stimulus and this response is inhibited by obesity and inflammation.	25299843
Inflammation, atherosclerotic	Altered Intercellular Communication	Measurement of high sensitivity CRP (hsCRP) and lipoprotein-associated phospholipase A2 (LpPLA2) provides information on systemic inflammation and stability of atherosclerotic plaques.	25300684
ARCN1 gene, Airway structure	Altered Intercellular Communication	Extracellular ATP is increased in the COPD affected lung and may play a key role in driving CS-induced airway inflammation, but the mechanism involved in ATP release has eluded researchers.	25301060
Airway structure	Altered Intercellular Communication	Mice were exposed to mainstream CS and airway inflammation assessed.	25301060
ARCN1 gene, Inflammation	Altered Intercellular Communication	This suggests a role of systemic inflammation in the early induction phase of COPD.	25301367
Inflammation, Carcinogenesis	Altered Intercellular Communication	S100/calgranulins (S100A8, S100A9 and S100A12) are key players of innate immune function and elevated levels are a characteristic feature of acute and chronic inflammation, and inflammation-associated carcinogenesis.	25302747
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We observed a significant association of rs58542926 and disease severity (P = 0.027), but not lobular inflammation or fibrosis; rs58542926 was not associated with levels of liver enzymes.	25302781
Cataract	Altered Intercellular Communication	Discrepant expression of cytokines in inflammation- and age-related cataract patients.	25303043
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	Studies suggest that hormonal states affect disease characteristics in women with rheumatoid arthritis (RA).	25303739
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Pentraxin 3 as a novel biomarker of inflammation in chronic obstructive pulmonary disease.	25303877
Inflammation, Ocular Hypotension, Hyphema	Altered Intercellular Communication	Two subjects developed mild transient hyphema, and none exhibited prolonged inflammation, persistent hypotony, or hypotony maculopathy.	25304276
Inflammation, Brain Injuries	Altered Intercellular Communication	Because inflammation is a strong mediator of secondary brain injury, a blunted proinflammatory response after rewarming may be beneficial.	25304549
Inferior vena cava structure, Inflammation	Altered Intercellular Communication	Early onset of periaortic inflammation after EVAR with inferior vena cava involvement: a case report.	25304907
Inflammation	Altered Intercellular Communication	Instead, the onset of periaortic inflammation after EVAR is a rare event with an unclear pathogenesis, time of onset, and clinical presentation.	25304907
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	To investigate whether polymorphisms of genes related to inflammation are associated with pathologic response (primary endpoint) in patients with rectal cancer treated with primary chemoradiation therapy (PCRT).	25304949
Rectal Carcinoma	Altered Intercellular Communication	If confirmed, an inflammation-related radiogenetic profile might be used to select patients with rectal cancer for preoperative combined-modality treatment.	25304949
Inflammation, Chronic disease, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation plays an important role in the cause of cardiovascular diseases and may contribute to the association linking an unhealthy diet to chronic age-related diseases.	25305231
Inflammation	Altered Intercellular Communication	These data suggest that maintaining and improving adherence to healthy dietary recommendations may reduce the risk of long-term inflammation.	25305231
Gastrointestinal inflammation	Altered Intercellular Communication	Central to the study is the hypothesis that enteropathogen infection contributes to undernutrition by causing intestinal inflammation and/or by altering intestinal barrier and absorptive function.	25305287
Inflammation, Bacterial Infections	Altered Intercellular Communication	The role of bacterial infection in stone formation is unclear but may include alteration of urinary components, acting as a nidus for crystallization, or inducing inflammation.	25306481
Airway structure, Asthma, Exacerbation	Altered Intercellular Communication	Persistent eosinophilic airway inflammation in asthma increases the risk of exacerbations.	25306557
ARCN1 gene, Inflammation	Altered Intercellular Communication	The results concerning IL-4 and IL-6 levels can be indicative of an attempt to control inflammation after the 6MWT in COPD patients.	25306916
Inflammation	Altered Intercellular Communication	Chronic transmural inflammation and mucosal regeneration probably facilitated epithelial misplacement, which secondarily developed cytologic atypia.	25307411
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Early administration of high-dose statin therapy in patients with ACS appears to improve biomarkers of inflammation within 8 h, which may translate into fewer ischemic events.	25307674
Sleeplessness, Inflammation, Depression, CTCAE, Anxiety, CTCAE 3.0	Altered Intercellular Communication	Sleep duration, insomnia, and markers of systemic inflammation: results from the Netherlands Study of Depression and Anxiety (NESDA).	25307717
Inflammation, Anxiety Disorders, Bipolar Disorder	Altered Intercellular Communication	Systemic inflammation has emerged as a potential pathway linking depressive and anxiety disorders with disease risk.	25307717
Sleeplessness, Inflammation, Psychiatric	Altered Intercellular Communication	Short and long sleep duration, as well as insomnia, are common among psychiatric populations and have previously been related to increased inflammation.	25307717
Sleeplessness, Inflammation	Altered Intercellular Communication	There were no clear associations between insomnia symptoms and levels of inflammation.	25307717
Inflammation, Psychiatric	Altered Intercellular Communication	Relationships between sleep duration and inflammation did not vary as a function of psychiatric diagnostic status.	25307717
Inflammation, Anxiety Disorders, Bipolar Disorder	Altered Intercellular Communication	These findings suggest that elevated levels of systemic inflammation may represent a mechanism linking long sleep duration and disease risk among those with and without depressive and anxiety disorders.	25307717
Anxiety, CTCAE 3.0, Inflammation, Bipolar Disorder, Atherosclerosis	Altered Intercellular Communication	Depressive symptoms and anxiety are predictive of prognosis, and have been associated with markers of inflammation that play a role in atherosclerosis.	25307791
Inflammation	Altered Intercellular Communication	The location of mast cells in different areas, their association with lymphocytes, fibroblasts, endothelial cells, and the phenomenon of degranulation helps to appreciate the release of various mediators and multiple interactions among these cells, leading to increased vascular permeability, angiogenic response, collagen synthesis, regulation of inflammation, bone resorption, and extracellular matrix destruction, thus contributing to the pathogenesis of these inflammatory lesions.	25307810
Hepatitis, Toxic effect	Altered Intercellular Communication	Gene-modified T cells survived, expanded and mediated a reduction in HBsAg levels without exacerbation of liver inflammation or other toxicity.	25308176
Airway structure, ARCN1 gene	Altered Intercellular Communication	We previously showed that low-dose azithromycin reduced airways inflammation in COPD subjects and we hypothesized that it would also reduce granzyme B production by CD8 T cells.	25308201
ARCN1 gene, Inflammation	Altered Intercellular Communication	We provide further evidence for the application of low-dose azithromycin as an attractive adjunct treatment option for controlling epithelial cell apoptosis, abnormal airway repair and chronic inflammation in COPD.	25308201
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Chronic inflammation has been postulated to be one mediating mechanism explaining the association between low socioeconomic position (SEP) and cardiovascular disease (CVD).	25309988
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is characterized by increased epithelial cell death and subsequent breakdown of the intestinal epithelial barrier, which perpetuates chronic intestinal inflammation.	25310532
Inflammation, Leukocytosis	Altered Intercellular Communication	In one of these cases, the patient presented with chronic intermittent polyarthritis, systemic inflammation, and leukocytosis.	25311252
Inflammation, Skeletal muscle structure	Altered Intercellular Communication	The influence of systemic inflammation on skeletal muscle in physically active elderly women.	25311555
Glaucoma, CTCAE, Conjunctivitis	Altered Intercellular Communication	Chronic conjunctival inflammation, caused by various reasons, for example long-term use of topical drugs and/or their preservatives, affects the outcome of glaucoma surgery by interfering with wound healing.	25312247
Inflammation, Mycobacterium Infections	Altered Intercellular Communication	To obtain a more definitive diagnosis, the patient underwent a CT-guided biopsy, which showed caseating granulomatous inflammation strongly suggestive of Mycobacterium infection.	25312889
melanoma, Inflammation	Altered Intercellular Communication	Melanoma BM showed considerable lymphocytic infiltrates and expression of PD-L1 in the majority of investigated specimens, with high PD-L1 expression found predominantly in regions of abundant inflammation.	25314639
Inflammation, Sacroiliac joint structure	Altered Intercellular Communication	Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were elevated (35 mm/h and 9.4, respectively) and Mennel's sign was present on both sides, indicating possible inflammation of the sacroiliac joints.	25315123
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) may be involved in the regulation of chronic inflammation in chronic obstructive pulmonary disease (COPD).	25315616
Intraocular inflammation, Endophthalmitis, CTCAE	Altered Intercellular Communication	There were no cases of intraocular inflammation or endophthalmitis.	25315663
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Epicardial adipose tissue inflammation is related to vitamin D deficiency in patients affected by coronary artery disease.	25315671
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	increased fat thickness and inflammation) have been described in coronary artery disease (CAD) patients.	25315671
Inflammation	Altered Intercellular Communication	Whether EAT inflammation may be linked to vitamin D deficiency is still unknown.	25315671
Inflammation	Altered Intercellular Communication	Whether maintaining an optimal vitamin D status may be helpful to reduce EAT inflammation and to prevent CAD and its progression needs further investigation.	25315671
Inflammation	Altered Intercellular Communication	All those protein aggregopathies show a state of chronic inflammation with microglia activation and production of proinflammatory cytokines.	25315814
Inflammation	Altered Intercellular Communication	In this context, it is hypothesized that the severity of the surrounding inflammation substantially contributes to disease progression and accelerated disease courses as seen in rpAD.	25315814
Communicable Diseases, Inflammation, Thalassemia	Altered Intercellular Communication	This information may be used to predict coexistent iron deficiency in b-thalassemia traits, in which concomitant infection or inflammation leads to normal ferritin levels.	25316665
Inflammation, Progranulins, Haploinsufficiency, Primary malignant neoplasm	Altered Intercellular Communication	All cause haploinsufficiency of progranulin, a protein involved in inflammation, tissue repair, and cancer.	25317628
Inflammation	Altered Intercellular Communication	In suspicious inflammation a further extended laboratory testing may become necessary (incl.	25317649
Inflammation	Altered Intercellular Communication	C-reactive protein (CRP) is a marker of arterial inflammation while lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is related to plaque instability.	25317678
Pneumonitis, Pneumonia	Altered Intercellular Communication	Female and estrogen-treated male mice show greater resistance to pneumococcal pneumonia, seen as greater bacterial clearance, diminished lung inflammation, and better survival.	25317947
Inflammation, Infiltration, Necrosis	Altered Intercellular Communication	Typically, there is no necrosis or acute inflammation, and giant cell infiltrates are frequent.	25318988
Inflammation, Neoplasm Metastasis, Traumatic injury	Altered Intercellular Communication	A relationship between inflammation and peritoneal metastasis has been reported; thus, we speculated that local inflammation resulting from chronic stimulus of mesh plugs and peritoneal trauma caused peritoneal metastasis at the repair sites.	25319214
Inflammation	Altered Intercellular Communication	In vitro experiments on monocytes and macrophages indicated that RA-SF promoted the acquisition of pro-inflammatory markers (INHBA, MMP12, EGLN3, CCR2) but led to a significant reduction in the expression of genes associated with homeostasis and inflammation resolution (FOLR2, SERPINB2, IGF1, CD36), thus confirming the pro-inflammatory polarization ability of RA-SF.	25319955
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Metabolic syndrome (MetS) is associated with low-grade inflammation, which may harmfully affect bone.	25322274
Littr√© hernia, Inflammation, Necrosis	Altered Intercellular Communication	The definition of Littre's hernia is based upon the protrusion of a MD through a potential abdominal opening accompanied in some cases by incarceration, inflammation, or necrosis.	25323188
RANGAP1 wt Allele, Inflammation, Spongiosis	Altered Intercellular Communication	The following distinctive confocal features for SD have been identified: spongiosis, dermal inflammation and horizontal orientation of dilated blood vessels.	25323385
palladium, Inflammation	Altered Intercellular Communication	These findings suggest that local peritoneal inflammation could contribute to poor clinical outcomes in PD patients.	25323428
Inflammation, Acute appendicitis NOS (disorder)	Altered Intercellular Communication	The severity of appendix inflammation was observed and rated using ARFI imaging in patients diagnosed with acute appendicitis.	25323836
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	ARFI imaging may be useful in guiding the clinical management of acute appendicitis, by helping its diagnosis and determining the severity of appendix inflammation.	25323836
Inflammation, Rosacea	Altered Intercellular Communication	Samples from 40 patients with clinicopathologic diagnosis of rosacea and facial skin tissue samples from 20 patients with no specific findings or milium without inflammation were retrieved.	25323904
Communicable Diseases, Inflammation	Altered Intercellular Communication	Inflammation is an essential protective part of the body's response to infection, yet many diseases are the product of inflammation.	25323997
Inflammation, Autoimmune Diseases, Tissue damage, Diabetes Mellitus, Heart Diseases, Rheumatoid Arthritis	Altered Intercellular Communication	For example, inflammation can lead to autoimmune disease and tissue damage, and is a key element in chronic health conditions such as heart disease, diabetes, rheumatoid arthritis, and also drives changes associated with aging.	25323997
Inflammation, Psychiatric Res. Interview f. Substance and Mental Disorders	Altered Intercellular Communication	Animal models therefore provide a prism through which the role of inflammation in health and disease can be viewed, and are important means by which to dissect mechanisms and identify potential therapies to be tested in the clinic.	25323997
Inflammation, Disease	Altered Intercellular Communication	The main goal was to bring together experts from biotechnology and academic organizations to examine and describe critical pathways in inflammation and place these pathways within the context of human disease.	25323997
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Interleukin-33 (IL-33) is a newly discovered proinflammatory cytokine belonging to the IL-1 cytokine family and involved in the development of chronic inflammation and cancer.	25324197
Inflammation, Neoplasms	Altered Intercellular Communication	Forty-nine patients were confirmed to have tumor recurrence and 13 patients were confirmed to have inflammation by pathology.	25324947
Inflammation, Myocarditis, CTCAE 5.0, Cardiomyopathies	Altered Intercellular Communication	Eosinophilic myocarditis is a rare condition in which inflammation of the heart results in an infiltrative cardiomyopathy that is often difficult to diagnose in the acute setting.	25325192
vascular inflammations, Obesity	Altered Intercellular Communication	Enhanced vascular inflammation is implicated as a pathophysiologic mechanism but obesity is confounding.	25325463
Slow shallow breathing, Inflammation, Hypoxemia, Apnea	Altered Intercellular Communication	The intermittent hypoxemia, rather than the number of apneas and hypopneas, appears to be primarily associated with enhanced inflammation.	25325463
Communicable Diseases, Inflammation, Dyssomnias	Altered Intercellular Communication	Sleep disturbance and aging are associated with increases in inflammation, as well as increased risk of infectious disease.	25325509
Inflammation, sleep loss	Altered Intercellular Communication	Older adults exhibit reduced toll-like receptor 4 stimulated cellular inflammation that, unlike in younger adults, is not activated after a night of partial sleep loss.	25325509
Communicable Diseases, Inflammation, Inflammatory disorder, sleep loss	Altered Intercellular Communication	Whereas sleep loss increases cellular inflammation in younger adults and may contribute to inflammatory disorders, blunted toll-like receptor activation in older adults may increase the risk of infectious disease seen with aging.	25325509
Inflammation	Altered Intercellular Communication	For patients with T2DM and CP, hyperglycemic status may exacerbate the inflammation state of gingival tissue by activating the NLRP3 pathway, and this abnormal host inflammatory response may contribute to further tissue breakdown.	25325516
Inflammation, diabetic	Altered Intercellular Communication	Compared with nondiabetic plaques, diabetic plaques had more inflammation and oxidative stress, along with a lesser SIRT6 expression and collagen content.	25325735
Inflammation, Polyneuropathy	Altered Intercellular Communication	Differential association between biomarkers of subclinical inflammation and painful polyneuropathy: results from the KORA F4 study.	25325880
vascular inflammations	Altered Intercellular Communication	Painful DSPN is linked to systemic subclinical and vascular inflammation in the older population independent of anthropometric, lifestyle, and metabolic confounders.	25325880
Inflammation, Hepatitis	Altered Intercellular Communication	Hepatitis is a descriptive term given for any inflammation of the liver.	25325934
Vasculitis, Haiti, Blood Vessel, Atherosclerosis	Altered Intercellular Communication	HT is associated with chronic vascular inflammation and remodeling, contributing to progressive vascular damage, and atherosclerosis.	25326158
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	We present a case of a 21-year-old woman who underwent colectomy for ulcerative colitis and later presented with new onset severe reversible inflammation of the upper respiratory tract.	25326560
Mesenteric Panniculitis, Mesentery, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Mesenteric panniculitis pertains to a group of uncommon disorders named sclerosing mesenteritis that present with different levels of inflammation and fibrosis of the small bowel mesentery.	25326572
Communicable Diseases, Inflammation	Altered Intercellular Communication	Circulating lipopolysaccharides (LPSs), associated with both infection and inflammation, may arise from the gastrointestinal tract microbiota, and the levels may be affected by daily nutrition.	25326898
Inflammation, Neoplasms	Altered Intercellular Communication	It may be originated from a desmoplastic reaction of the retroperitoneum to the presence of malignant cells, to the action of cytokines secreted by the tumor or a reactive inflammation.	25327326
Gastroesophageal reflux disease, Inflammation, Barrett Esophagus	Altered Intercellular Communication	The severity of abnormal acid reflux occuring parallel with the incompetent function of the damaged LES triggers not only inflammation in the gastroesophageal junction (GEJ), but also metaplastic process, and the development of Barrett's esophagus.	25327403
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	We tested a mediational model in which chronic financial strain among African American women contributes to elevated serum inflammation markers, which, in turn, lead to increased haemoglobin A1C (HbA1c) levels and risk for type 2 diabetes.	25327694
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Findings have implications for interventions that boost economic security and foster effective coping as well as medical interventions that reduce serum inflammation to prevent the onset of type 2 diabetes.	25327694
Vascular Diseases, Pterygium Of Conjunctiva And Cornea, Conjunctivitis, Glaucoma, CTCAE, Disease	Altered Intercellular Communication	Cases with a history of glaucoma or glaucoma suspect, prior pterygium surgery, pterygium with concurrent ocular surface and lid disease, conjunctival inflammation and scarring, pseudo-pterygium or collagen vascular disease were excluded.	25327918
Liver carcinoma	Altered Intercellular Communication	Dynamic changes of the inflammation-based index predict mortality following chemoembolisation for hepatocellular carcinoma: a prospective study.	25327965
FAM126A gene	Altered Intercellular Communication	The inflammation-based index (IBI) has previously been shown to independently predict overall survival (OS) in all stages of HCC.	25327965
Inflammation, Ischemia	Altered Intercellular Communication	No signs of inflammation during knee surgery with ischemia: a study involving inhaled nitric oxide.	25328284
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by chronic pulmonary and systematic inflammation.	25329073
Inflammation, Lung Neoplasms	Altered Intercellular Communication	Lung tumors showed higher inflammation than gastrointestinal ones.	25329228
Inflammation, Urolithiasis, physiopathological	Altered Intercellular Communication	Urothelial dysfunction and increased suburothelial inflammation of urinary bladder are involved in patients with upper urinary tract urolithiasis--clinical and immunohistochemistry study.	25329457
Inflammation, Urolithiasis, physiopathological	Altered Intercellular Communication	To investigate the urothelial dysfunction and inflammation of urinary bladder in patients with upper urinary tract (UUT) urolithiasis through the results of cystoscopic hydrodistension and immunohistochemistry study.	25329457
Inflammation, Urolithiasis, physiopathological, Urinary Bladder	Altered Intercellular Communication	Urothelial dysfunction and increased suburothelial inflammation and apoptosis are highly prevalent in the bladders of UUT urolithiasis patients, indicating inflammation cross-talk between UUT and urinary bladder.	25329457
Inflammation, Overweight	Altered Intercellular Communication	Dietary patterns differently associate with inflammation and gut microbiota in overweight and obese subjects.	25330000
Inflammation, Pustulosis of Palms and Soles	Altered Intercellular Communication	Vesicular LL-37 contributes to inflammation of the lesional skin of palmoplantar pustulosis.	25330301
Gingivitis, Inflammation, Attachment (action)	Altered Intercellular Communication	The second group consisted of 28 patients, 41-70 years of age, with overt signs of gingival inflammation but no attachment loss (gingivitis group).	25330403
Airway structure, Allergy - Charge Type Reason	Altered Intercellular Communication	Evaluation of high-sensitivity serum CRP levels compared to markers of airway inflammation and allergy as predictors of methacholine bronchial hyper-responsiveness in children.	25331535
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To evaluate associations between lipid levels, inflammation, and rheumatoid arthritis (RA) disease activity, at baseline and during treatment, with the risk of major adverse cardiovascular events (MACE) in tocilizumab-treated patients with RA.	25332171
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor-a (TNF) and toll-like receptors (TLR) are important mediators of inflammation.	25332681
Inflammation, Dental Plaque	Altered Intercellular Communication	The level of plaque accumulation and gingival inflammation with the use of lingual plate and bar dentures were determined and compared.	25335375
Inflammation, Granulation finding, Malignant Neoplasms	Altered Intercellular Communication	Clinical diagnosis based on 2-[18F]fluoro-2 deoxy-D glucose uptake is sometimes limited by the fact that 2-[18F]fluoro-2 deoxy-D glucose is taken up by not only malignant tumor cells but also macrophages and tissues with granulation or inflammation.	25335527
THANATOPHORIC DYSPLASIA, TYPE I (disorder), Tardive Dyskinesia	Altered Intercellular Communication	Overactivity of dopaminergic neurotransmission is a putative mechanism of tardive dyskinesia (TD).	25336319
ARCN1 gene	Altered Intercellular Communication	Exhaled Hydrogen Sulfide Predicts Airway Inflammation Phenotype in COPD.	25336529
Airway structure, ARCN1 gene	Altered Intercellular Communication	The role of exhaled H2S as a marker of airway inflammation and its relationship with COPD severity remain to be determined.	25336529
Airway structure, ARCN1 gene	Altered Intercellular Communication	Airway inflammation was classified in 77 COPD subjects based on the presence of inflammatory cells in induced sputum.	25336529
Hepatic schistosomiasis, Granulomatous inflammation, Pancreatitis, Hypermetabolism	Altered Intercellular Communication	F-18 FDG hypermetabolism in mass-forming focal pancreatitis and old hepatic schistosomiasis with granulomatous inflammation misdiagnosed by PET/CT imaging.	25337288
Hepatic schistosomiasis, Granulomatous inflammation, Pancreatitis	Altered Intercellular Communication	Postoperative pathology was consistent with chronic pancreatitis and old hepatic schistosomiasis associated with granulomatous inflammation of the liver.	25337288
Hepatic schistosomiasis, Granulomatous inflammation, Pancreatic carcinoma	Altered Intercellular Communication	This case of mass-forming pancreatitis and granulomatous inflammation in old hepatic schistosomiasis mimicked metastatic pancreatic cancer on PET/CT.	25337288
TNM Staging System, Neoplasms, Thyroid carcinoma, Inflammation	Altered Intercellular Communication	ER-alpha and ER-beta expression in differentiated thyroid cancer: relation with tumor phenotype across the TNM staging and peri-tumor inflammation.	25338203
Inflammation, Thyroid carcinoma	Altered Intercellular Communication	Thyroid cancer may express estrogen receptors (ERs) and various grades of peri-tumor inflammation.	25338203
Meningitis	Altered Intercellular Communication	The MRI performed showed pachymeningeal and leptomeningeal inflammation.	25338348
palladium, Inflammation	Altered Intercellular Communication	We previously reported that lower serum magnesium is associated with poorer nutrition status, impaired cellular health, and increased inflammation in peritoneal dialysis (PD) patients.	25338428
Inflammation, Primary malignant neoplasm, Breast Carcinoma	Altered Intercellular Communication	Chronic inflammation is suggested to be associated with specific cancer sites, including breast cancer.	25339205
Inflammation	Altered Intercellular Communication	Complete decompression of the pancreatic ducts in the head of pancreas and full length drainage of the main pancreatic duct from the head of pancreas to the tail may be important in the Frey procedure to prevent recurrence of acute inflammation.	25339262
Uremia, Inflammation	Altered Intercellular Communication	To explore the relation between high leptin and inflammation in uremic patients.	25339482
Uremia, Inflammation	Altered Intercellular Communication	The high level of leptin and correlated inflammation were involved in the initiation and development of uremia; moreover, leptin was an important mediator.	25339482
Hepatic inflammation	Altered Intercellular Communication	FXR agonist GW4064 alleviates endotoxin-induced hepatic inflammation by repressing macrophage activation.	25339829
Hepatic inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	To examine the effect of farnesoid X receptor (FXR) activation by GW4064 on endotoxin-induced hepatic inflammation in nonalcoholic fatty liver disease (NAFLD) and the underlying mechanism.	25339829
Hepatic inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Activation of FXR by GW4064 alleviated hepatic inflammation induced by endotoxin in a murine NAFLD model fed an HF diet as reflected by reduced serum levels of aspartate aminotransferase and alanine aminotransferase.	25339829
Hepatic inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	FXR activation attenuates LPS-induced hepatic inflammation in murine NAFLD by reducing expression of proinflammatory cytokines in macrophages.	25339829
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The importance of inflammation is increasingly noticed in cancer.	25340395
ARCN1 gene, Alveolar, Colonization, Airway structure, Tissue damage	Altered Intercellular Communication	Colonization by bacteria may further synergize, amplify, or trigger pathways of tissue damage started by cigarette smoke, contributing to the characteristic airway inflammation and alveolar destruction of COPD.	25340840
Inflammation	Altered Intercellular Communication	are present in more severe COPD disease, and increase inflammation in a mouse model of smoke exposure.	25340840
vascular inflammations, Hypertension, CTCAE, Endothelial dysfunction	Altered Intercellular Communication	Interleukin 17 drives vascular inflammation, endothelial dysfunction, and arterial hypertension in psoriasis-like skin disease.	25341795
Inflammation, physiopathological	Altered Intercellular Communication	We aimed to test the hypothesis that overproduction of IL-17A in the skin leading to dermal inflammation may systemically cause vascular dysfunction in psoriasis-like skin disease.	25341795
Inflammation, Obesity	Altered Intercellular Communication	These findings point to the adaptive immune system as a potential mediator between obesity and insulin resistance or inflammation.	25341798
Inflammation	Altered Intercellular Communication	The formyl peptide receptor (FPR) subtype FPR2/ALX transduces pro-inflammatory responses and participates in the resolution of inflammation depending on activation.	25341894
Inflammation, Intracranial Aneurysm	Altered Intercellular Communication	Evidence has shown that inflammation acts as a critical contributor to the pathogenesis of intracranial aneurysm (IA), a potentially devastating clinical problem.	25342285
Inflammation	Altered Intercellular Communication	T cell immunoglobulin and mucin protein 3 (Tim-3) is a negative regulatory molecule and plays important roles in the inflammation process.	25342285
Uveomeningoencephalitic Syndrome, Inflammation	Altered Intercellular Communication	This study was set up to investigate the expression of IL-37 in Vogt-Koyanagi-Harada (VKH) disease and to explore its possible regulatory role during inflammation.	25343528
Uveomeningoencephalitic Syndrome, Intraocular inflammation	Altered Intercellular Communication	VKH patients treated with corticosteroids combined with CsA showed a regression of the intraocular inflammation, and treatment was associated with an enhanced IL-37 production.	25343528
Inflammation, Primary malignant neoplasm, Prostate carcinoma	Altered Intercellular Communication	In recent years the role of inflammation in cancer etiology has gained attention and several studies have suggested that acetylsalicylic acid and other nonsteroidal anti-inflammatory drugs may have chemopreventive activity and reduce the risk of prostate cancer.	25343540
Inflammation	Altered Intercellular Communication	Serum HMGB1 is elevated in patients with MG and may play a key role in the inflammation of the neuromuscular junction.	25344065
Inflammation, Neurogenic arthropathy, Diabetic Foot	Altered Intercellular Communication	Charcot neuro-osteoarthropathy (CN) is a rare complication of diabetic foot syndrome associated with chronic inflammation of the foot and severe, limb-threatening musculoskeletal deformities.	25344769
Communicable Diseases, Cardiac complication, Inflammation	Altered Intercellular Communication	Therefore, the aim of our study was to examine the influence of intimal infection and systemic inflammation on cardiovascular complications after coronary intervention.	25344890
Inflammatory Bowel Diseases	Altered Intercellular Communication	Non-invasive monitoring of inflammatory bowel disease is an unmet clinical need as patients in clinical remission may have residual mucosal inflammation preceding clinical relapse.	25344905
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The postoperative material was assessed by the patologist, and it was described focal chronic inflammation of the head of pancreas with fibrosis involving the wall of the duodenum.	25345278
Hepatic inflammation	Altered Intercellular Communication	Histopathologically, platelet area of the liver tissues was positively correlated with hepatic inflammation (P = 0.02).	25345682
Hypersplenism, Hepatic inflammation, Thrombocytopenia	Altered Intercellular Communication	Hepatic inflammation contributes to the accumulation of platelets in liver; therefore, in patients with high serum ALT level, improvement of thrombocytopenia by the elimination of hypersplenism was limited.	25345682
Necrotizing granulomatous inflammation, Inflammation, Bacterial Infections	Altered Intercellular Communication	A biopsy of the ileal mucosa revealed inflammation with noncaseating granulomas possibly due to bacterial infection.	25346193
Intraocular inflammation	Altered Intercellular Communication	Subconjunctival injection of XG-102, a JNK inhibitor peptide, in patients with intraocular inflammation: a safety and tolerability study.	25347151
Coma, Post-Head Injury, Inflammation	Altered Intercellular Communication	Twenty patients with post-surgery or post-traumatic intraocular inflammation were assigned to 1 of the 4 dose escalating (45, 90, 450, or 900 mg XG-102) groups of 5 patients each.	25347151
Intraocular inflammation	Altered Intercellular Communication	All patients experienced a decrease in intraocular inflammation as of 24 h post-administration and this decrease was sustained up to 28 days thereafter.	25347151
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Cystic fibrosis airway epithelium remodelling: involvement of inflammation.	25348090
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Chronic inflammation is a hallmark of cystic fibrosis (CF) lung disease and airway epithelium damage and remodelling are important components of lung pathology progression in CF.	25348090
Inflammation, Basal cell hyperplasia	Altered Intercellular Communication	In comparison to non-CF epithelium, CF epithelium regeneration in the absence of exogenous inflammation was higher and exhibited basal cell hyperplasia.	25348090
Inflammation, Nesidioblastosis	Altered Intercellular Communication	This remodelling, together with goblet cell hyperplasia induced by exogenous inflammation and alteration of ciliated cell differentiation, may worsen mucociliary clearance impairment, leading to injury.	25348090
Inflammation	Altered Intercellular Communication	Inflammation may represent a common physiological pathway linking both short and long sleep duration to mortality.	25348127
Inflammation, Pneumonia	Altered Intercellular Communication	Since aged pneumonia patients often have repeated episodes of aspiration pneumonia, the pathogenesis may involve chronic inflammation.	25348279
Inflammation, Pneumonia	Altered Intercellular Communication	No previous studies have examined chronic inflammation or vascular changes in aspiration pneumonia or its mouse models.	25348279
Inflammation	Altered Intercellular Communication	In the lung, the aspiration model showed the presence of chronic inflammation and exaggerated lymphangiogenesis.	25348279
Inflammation	Altered Intercellular Communication	Human lung samples also showed the presence of chronic inflammation and exaggerated lymphangiogenesis, suggesting the relevance of the model to the disease.	25348279
Kidney Failure, Chronic, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Patients with end-stage renal disease, especially those with inflammation, are at an increased risk of premature mortality, primarily because of cardiovascular disease.	25348369
Inflammation, Bronchopulmonary Dysplasia	Altered Intercellular Communication	The role of inflammation in the bronchopulmonary dysplasia (BPD) survivors is indistinct.	25348705
Inflammation, Carcinogenesis, Infection	Altered Intercellular Communication	Infections and inflammation in the prostate play a critical role in carcinogenesis, and S100A8 and S100A9 are key mediators in acute and chronic inflammation.	25348783
Inflammation, Brain Injuries	Altered Intercellular Communication	IATH did not affect biological markers of inflammation or brain damage or clinical outcome.	25348858
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Systemic inflammation as evidenced by the Glasgow prognostic score (GPS) predicts cancer-specific survival in various types of cancer.	25348884
Hippocampal atrophy	Altered Intercellular Communication	This study shows an association between calcified cysticerci and hippocampal atrophy and raises the possibility of an inflammation-mediated hippocampal damage as the responsible mechanism for these findings.	25349375
Inflammatory Bowel Diseases, Inflammation, Neoplasms, Colorectal Neoplasms, CRNKL1 wt Allele	Altered Intercellular Communication	Chronic inflammation plays a key role in the pathogenesis of colorectal neoplasia (CRN) associated with inflammatory bowel disease, but it is not clear whether inflammation is a cause or an effect of tumours in sporadic CRN.	25350634
Inflammation, Cerebral Infarction	Altered Intercellular Communication	Mounting evidence has suggested that inflammation associated with interleukin (IL)-6 and T-helper (Th)17 cells, has a role in the development of atherosclerotic cerebral infarction (ACI).	25351283
Inflammation	Altered Intercellular Communication	IGF-I plays a role in the regulation of immunity, bone metabolism and inflammation.	25352179
Stomatitis, Deglutition Disorders, Inflammation	Altered Intercellular Communication	Most common grade >=3 adverse events (AEs) were dysphagia (30%), stomatitis (33%), and mucosal inflammation (27%).	25352401
Inflammation	Altered Intercellular Communication	This reinforces the important role of inflammation on the outcomes of this group of patients.	25352506
Inflammation, physiopathological	Altered Intercellular Communication	The lifestyle intervention reversed this insulin-induced vascular dysfunction in parallel to decreased inflammation level.	25353072
Inflammation, Neoplasms	Altered Intercellular Communication	Chronic inflammation is considered to be one of the hallmarks for tumor initiation and progression.	25353097
Inflammation, Atherosclerosis	Altered Intercellular Communication	Although both are novel cardiovascular risk factors associated with inflammation and atherosclerosis, the specific relationship between MBPS and serum GGT is unknown.	25355010
Diarrhea, Bronchospasm, Neoplasms, Abdominal Pain	Altered Intercellular Communication	Her tumor is functional, meaning it demonstrates hormonal hypersecretion which causes flushing, diarrhea, bronchospasm, and abdominal pain.	25355025
Inflammation, Critical Illness	Altered Intercellular Communication	In this pilot cohort of critically ill children, transfusion with older prestorage leukoreduced RBCs was associated with persistence of innate immune suppression and systemic inflammation.	25355535
Inflammation	Altered Intercellular Communication	Biopsy specimens from the oral mucosa revealed detachment of epithelial basement membrane and subepithelial lamina propria with slight chronic inflammation.	25355555
Necrotizing granulomatous inflammation, Necrosis	Altered Intercellular Communication	A biopsy of this lesion, taken through the duodenal wall, showed a histiocytic granulomatous inflammation with necrosis.	25355744
Nephritis, Interstitial, Tubulointerstitial nephritis and uveitis, Uveitis	Altered Intercellular Communication	Tubulointerstitial nephritis and uveitis (TINU) syndrome is characterized by tubulointerstitial and ocular inflammation.	25356569
Inflammation, Kit Ligand, human	Altered Intercellular Communication	There is accumulating evidence that inflammation plays a major role in the development of the slow coronary flow (SCF) phenomenon.	25356814
Immunologic Deficiency Syndromes, Chronic inflammation	Altered Intercellular Communication	Four patients with immune deficiency showed signs and symptoms of chronic inflammation.	25356955
Inflammation, Chronic abdominal pain, Ulcerative Colitis	Altered Intercellular Communication	We undertook a study to test the hypothesis that inflammation alters peripheral sensory mechanisms, thereby contributing to chronic abdominal pain in ulcerative colitis (UC).	25358061
Inflammation, Pain Distress Question	Altered Intercellular Communication	Mucosal nerve fiber density did not correlate with any measures of inflammation or pain.	25358061
Refractory anemias, Tumor necrosis, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor (TNF) and, possibly, lymphotoxin alpha (LTa) signaling contribute to inflammation and rheumatoid arthritis (RA) pathogenesis.	25359150
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The associations between S100A4 levels, inflammation, disease activity, muscle strength and cancer development were evaluated.	25359220
Malignant neoplasm of prostate, Kaposi Sarcoma, Prostate carcinoma, prostatitis, Structure of posterior cerebral artery	Altered Intercellular Communication	Human herpesvirus type 8 (HHV-8), a gamma herpesvirus associated with Kaposi's sarcoma, has been proposed as a candidate risk factor for prostate cancer (PCa) because of its detection in benign and malignant prostate specimens, and its relation with histologic prostatic inflammation.	25359302
Inflammation	Altered Intercellular Communication	Chronic inflammation in a long-term cohort of HIV-infected patients according to the normalization of the CD4:CD8 ratio.	25360575
Inflammation, Immunosenescence	Altered Intercellular Communication	As CD4:CD8 inversion is considered a marker of immune-senescence, we aimed to assess if it was associated with the chronic inflammation state in aging patients with HIV.	25360575
Inflammation	Altered Intercellular Communication	Chronic inflammation in patients aging with HIV does not seem to be directly dependent on the CD4:CD8 ratio.	25360575
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Chronic inflammation is often related to the occurrence and growth of various malignancies.	25360699
Airway structure	Altered Intercellular Communication	The wingless/integrated (Wnt) signaling pathways are responsible for several cellular processes, including airway inflammation and remodeling while cAMP-PKA cascade can activate the Wnt signaling.	25360795
Inflammation	Altered Intercellular Communication	Endothelial dysfunction associated with systemic inflammation can contribute to organ injury/failure following cardiac surgery requiring cardiopulmonary bypass (CPB).	25360813
Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	Plasma and endothelial markers of inflammation [interleukin (IL) -6, -8, -10: von Willibrand factor (vWF) and angiopoeitin-2 (Ang-2)] and the AKI marker, neutrophil gelatinase-associated lipocalin (NGAL), were also measured by ELISA.	25360813
Inflammation, Necrosis, Pathological Dilatation, Stenosis Morphology, Occluded, Vasculitis, CTCAE	Altered Intercellular Communication	Coronary vasculitis is a group of conditions occurring either independently or associated with another diseases characterized by an inflammation of the blood vessel's wall and subsequent fibrinoid necrosis, occlusion, stenosis, or aneurismal dilatations.	25361059
Inflammation, Hematoma, Ischemia, Discitis, Hypersensitivity	Altered Intercellular Communication	No major complications like inflammation (especially spondylodiscitis), large haematomas requiring surgery, severe allergic reactions or spinal ischaemia occurred.	25363255
Inflammation, Prostate carcinoma, prostatitis	Altered Intercellular Communication	Prostate cancer patients with prostatitis showed significantly higher IL-2R expression than those without inflammation (p < 0.03).	25363611
Hyperparathyroidism, Secondary, Chronic Kidney Diseases, HYPERPARATHYROIDISM, NEONATAL SEVERE	Altered Intercellular Communication	Secondary hyperparathyroidism (SHPT) is one of the major complications of chronic kidney disease (CKD) and is associated with elevated serum intact parathyroid hormone (iPTH).	25363733
Granuloma, Intraocular inflammation	Altered Intercellular Communication	A large granuloma infiltrating optic nerve head was visible at funduscopic examination along with diffuse intraocular inflammation.	25363855
Inflammation, Observation Method - Coagulation, Musculoskeletal	Altered Intercellular Communication	Activation of markers of inflammation, coagulation and fibrinolysis in musculoskeletal trauma.	25364904
Inflammation, Observation Method - Coagulation, Wounds and Injuries	Altered Intercellular Communication	Traumatic injury induces changes in mediators of inflammation and coagulation, but the pivotal roles of inflammation and coagulation has not been precisely clarified.	25364904
Inflammation, Observation Method - Coagulation, Musculoskeletal	Altered Intercellular Communication	Therefore we have studied markers of inflammation and coagulation after a standardized musculoskeletal trauma like total hip replacement surgery.	25364904
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Major musculoskeletal surgery causes changes of the inflammatory, coagulatory and fibrinolytic cascades in stable patients, but with no correlations between inflammation and coagulation and fibrinolysis.	25364904
Inflammation, Osseous metaplasia, Retinal Detachment, Tuberculosis, Pulmonary, Traumatic injury	Altered Intercellular Communication	Osseous metaplasia may occur in phthisis bulbi, usually caused by long-standing retinal detachment, ocular trauma, or inflammation.	25364973
Inflammation, Rupture, Plaque, Atherosclerotic	Altered Intercellular Communication	Biomechanics and inflammation in atherosclerotic plaque erosion and plaque rupture: implications for cardiovascular events in women.	25365517
Rupture, Inflammation, Dental Plaque	Altered Intercellular Communication	Given obvious differences in morphology between plaque erosion and rupture, we hypothesized that inflammation in general as well as the association between local mechanical strain and inflammation known to exist in plaque rupture may not occur in plaque erosion.	25365517
Inflammation, Dental Plaque	Altered Intercellular Communication	Using lesion-specific computer modeling of solid mechanics, we calculated the stress and strain distribution for each plaque and determined if there were any relationships with markers of inflammation.	25365517
Rupture, Inflammation, Dental Plaque	Altered Intercellular Communication	In contrast to classic plaque rupture, plaque erosion was not associated with markers of inflammation and mechanical strain.	25365517
Inflammation	Altered Intercellular Communication	It is hypothesized that unphysiologically increased loading in the AAA wall triggers biological tissue reaction, such as inflammation or regenerative processes, causing elevated FDG-metabolic activity.	25365658
Airway structure	Altered Intercellular Communication	Exhaled nitric oxide is a noninvasive measure of airway inflammation that can be detected by a handheld device.	25366981
Inflammation, HIV Infections	Altered Intercellular Communication	Our results show that HIV infection is associated with increased glucose metabolism in monocytes and that Glut1 expression by proinflammatory monocytes is a potential marker of inflammation in HIV-infected subjects.	25367121
Inflammation	Altered Intercellular Communication	PGC-1b overexpression leads to the attenuation of macrophage-mediated inflammation.	25367151
Refractory anemias, Inflammation, Rheumatoid Arthritis, Synovitis	Altered Intercellular Communication	To intra-individually assess the association of inflammation severity and cartilage composition measured by RAMRIS synovitis sub-score and delayed gadolinium-enhanced magnetic resonance imaging of the cartilage (dGEMRIC) of metacarpophalangeal (MCP) joints in patients with rheumatoid arthritis (RA).	25367672
Inflammation, Cartilage damage, Synovitis	Altered Intercellular Communication	To test the association of inflammation severity and cartilage damage and in order to eliminate inter-patient confounders, each patient's MCP 2 and 3 were dichotomized into the joint with more severe synovitis versus the joint with less severe synovitis for a paired Wilcoxon test of dGEMRIC value.	25367672
Inflammation	Altered Intercellular Communication	We have previously shown that chronic inflammation results in immunosuppression associated with CD247 downregulation in T lymphocytes.	25368105
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Type 2 diabetes mellitus (T2DM) is known to be associated with chronic inflammation.	25368105
Inflammation, diabetic	Altered Intercellular Communication	Our results suggest the use of CD247 as a biomarker in diabetic patients for evaluating the state of chronic inflammation that contributes to morbidity and mortality in this disease and for the prediction of future cardiovascular events.	25368105
Inflammation	Altered Intercellular Communication	In the extracellular compartment, it exhibits cytokine-/adipokinelike properties, suggesting that it stands at the crossroad between metabolism and inflammation.	25368373
Tumor necrosis, Inflammation, Peptic Ulcer	Altered Intercellular Communication	Tumor necrosis factor a (TNF-a) encoded by TNFA is a key mediator in inflammation, a precursor condition for peptic ulceration.	25368751
Inflammation, Coronary Artery Disease, Non-cardiac chest pain	Altered Intercellular Communication	Inhibition of inflammation mediates the protective effect of atorvastatin reload in patients with coronary artery disease undergoing noncardiac emergency surgery.	25369444
Inflammation, Carcinogenesis, Papillary Urothelial Neoplasm	Altered Intercellular Communication	Chronic inflammation in the papillary urothelial neoplasm of low malignant potential (PUNLMP)may contribute to carcinogenesis, including that of BCa, via poorly understood mechanisms.	25369740
Acute and chronic inflammation	Altered Intercellular Communication	The cause is unknown but is associated with low estrogen levels and chronic vulval inflammation.	25369765
Airway structure, ARCN1 gene	Altered Intercellular Communication	Genetic variants in ADAM33 are associated with airway inflammation and lung function in COPD.	25369941
ARCN1 gene, Inflammation, Genes, Recessive	Altered Intercellular Communication	We found that T1, T2 and Q-1 were significantly associated with the changes of pulmonary function and components of cells in sputum of COPD, and T1 and Q-1 were significantly associated with cytokines and mediators of inflammation in airway of COPD in recessive models.	25369941
Airway structure	Altered Intercellular Communication	10 haplotypes were significantly associated with transfer factor of the lung for carbon monoxide in the disease state, 4 haplotypes were significantly associated with forced expiratory volume in one second, and other haplotypes were associated with airway inflammation.	25369941
ARCN1 gene, Airway structure	Altered Intercellular Communication	We confirmed for the first time that ADAM33 was involved in the pathogenesis of COPD by affecting airway inflammation and immune response in an East Asian population.	25369941
Inflammatory Bowel Diseases, Inflammation, Colitis	Altered Intercellular Communication	Histological inflammation was found in 45 (68%) patients: 24 had a diagnosis of inflammatory bowel disease (IBD) while 21 reported miscellaneous conditions (5 microscopic colitis, 2 eosinophilic colitis, and 14 nonspecific chronic colitis).	25369978
Inflammation, Ichthyosis Bullosa of Siemens, Irritable Bowel Syndrome	Altered Intercellular Communication	The diagnosis in the 21 (32%) patients without inflammation was irritable bowel syndrome (IBS).	25369978
Inflammation	Altered Intercellular Communication	Median FC values were 268 ug/g (95% CI, 151-343) and 49 ug/g (95% CI, 23-101) in patients with and without inflammation, respectively (p = 0.0001).	25369978
Inflammatory Bowel Diseases, Inflammation, Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	AUC value of FC was 0.811 (Se = 68.9%, Sp = 71.4%, PPV = 83.8%, and NPV = 56.3% with a cutoff value of 100 ug/g) for discriminating between patients with and without inflammation and 0.931 (Se = 87.5%, Sp = 90.5%, PPV = 91.3%, and NPV = 86.4% with a cutoff value of 150 ug/g) for discriminating between patients with IBS and IBD.	25369978
Gastrointestinal inflammation	Altered Intercellular Communication	FC appears to be a reliable noninvasive biomarker of intestinal inflammation useful to improve the appropriateness of colonoscopy requests.	25369978
Cessation of life, Inflammation, Sepsis	Altered Intercellular Communication	Nucleosomes are markers of cell death, and extracellular cell-free DNA has been suggested to play an important role in inflammation and has been demonstrated to correlate with severity and outcome in sepsis patients.	25370187
Inflammation, Ischemic stroke	Altered Intercellular Communication	Incremental predictive value of carotid inflammation in acute ischemic stroke.	25370590
Inflammation, Infiltration, diabetic	Altered Intercellular Communication	And there wss a lot of inflammation and foam cell infiltration in the radial artery intima of the diabetic patients.	25370764
Inflammation, diabetic	Altered Intercellular Communication	Gene sets upregulated in diabetic myotubes were associated predominantly with inflammation.	25370850
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In other words, fibrosis had advanced from the time of extensive cell infiltration in patients with IgG4-RKD and inflammation was relieved by corticosteroid.	25371379
Breast Carcinoma	Altered Intercellular Communication	Hormonal influences at critical periods may contribute to morphologic differences in the breast associated with breast cancer risk later in life.	25371447
Inflammation, Atherosclerosis	Altered Intercellular Communication	Leukotrienes (LTs), highly bioactive lipid mediators play a major role in inflammation, wound healing and in the development of atherosclerosis.	25371530
Inflammation, Translucent	Altered Intercellular Communication	Computed tomography showed gingival inflammation and lucencies of several teeth.	25372197
Communicable Diseases, Inflammation	Altered Intercellular Communication	Because there were no signs of infection or inflammation, surgical intervention was avoided.	25372198
Chorea Gravidarum	Altered Intercellular Communication	Both a genetic mutation and pregnancy-induced hormonal changes played possible roles in the development and progress of unilateral generalized KP in this patient.	25372256
Inflammation, Choroiditis, Multifocal	Altered Intercellular Communication	Idiopathic multifocal choroiditis with peripapillary zonal inflammation: a multimodal imaging analysis.	25372332
Unknown (origin) (qualifier value), Inflammation, Choroiditis, Chorioretinal atrophy	Altered Intercellular Communication	To report a case of idiopathic multifocal choroiditis with transient peripapillary zonal inflammation that was followed with multimodal imaging and explain the mechanism by which chorioretinal atrophy may occur.	25372332
Inflammation, Choroiditis, Chorioretinal atrophy, Inflammatory disorder, Atrophic	Altered Intercellular Communication	Multifocal choroiditis is an inflammatory disorder affecting the outer photoreceptors, ellipsoid layer, retinal pigment epithelium, and choroid; and areas of acute inflammation may improve over time but can also leave permanent chorioretinal atrophy including focal lesions or peripapillary zonal atrophy.	25372332
Vasculitis, Thrombophilia	Altered Intercellular Communication	Combined cases have mostly been attributed to rheological causes like thrombophilia, vessel wall inflammation, and mechanical compression.	25372333
Inflammation, Necrosis, Drug Allergy	Altered Intercellular Communication	An oral mucosal biopsy revealed V-shaped coagulative necrosis, intraepithelial and superficial acute and lymphoplasmacytic inflammation, consistent with drug hypersensitivity reaction.	25372334
Inflammatory abnormality of the eye	Altered Intercellular Communication	At 6 months of follow-up, her vision in the left eye was stable at 6/24 (Snellen) with no ocular inflammation.	25372437
Retinal Detachment, Inflammation, Hemorrhage	Altered Intercellular Communication	There was no retinal detachment, inflammation, or hemorrhage.	25372445
Inflammation, Vasculitis, CTCAE, Granuloma	Altered Intercellular Communication	Pulmonary biopsy disclosed chronic inflammation with no evidence of granuloma formation or vasculitis.	25372516
Intraocular inflammation, Endophthalmitis, CTCAE, Keratitis caused by infection	Altered Intercellular Communication	Chronic endophthalmitis should be suspected in patients who develop persistent intraocular inflammation after infectious keratitis.	25372524
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are two commonly used measures of inflammation in rheumatoid arthritis (RA).	25373740
Refractory anemias, Inflammation	Altered Intercellular Communication	As current RA treatment guidelines strongly emphasize early and aggressive treatment aiming at fast remission, optimal measurement of inflammation becomes increasingly important.	25373740
Inflammation, Polymyositis, Necrosis	Altered Intercellular Communication	We report on a novel finding whereby five of the seven patients who underwent multiple biopsies throughout their disease demonstrated a transformation of their histological diagnosis, with four progressing from having myofibre necrosis with minimal or no inflammation to a diagnosis of polymyositis.	25373816
Inflammation	Altered Intercellular Communication	PTX3 may represent a rapid marker of local inflammation.	25373851
ARCN1 gene, Inflammation	Altered Intercellular Communication	Cigarette smoking promotes inflammation in patients with COPD by affecting the polarization and survival of Th/Tregs through up-regulation of muscarinic receptor 3 and 5 expression.	25375131
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The progress of inflammation and oxidative stress in patients with chronic kidney disease.	25375354
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The variations and their correlation of inflammation and oxidative stress in chronic kidney disease (CKD) have not been thoroughly understood.	25375354
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Biomarkers of inflammation and oxidative stress were measured in a cohort of 176 patients with CKD ranging from stage 1 to 5 and 67 healthy controls.	25375354
Inflammation, Kidney Diseases	Altered Intercellular Communication	Correlation analysis in levels between inflammation and oxidative stress was also performed with estimated glomerular filtration rate (eGFR) using the Modification of Diet in Renal Disease (MDRD) formula.	25375354
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation and oxidative stress interacted with each other and played pivotal roles in the development of CKD.	25375354
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Variation in eGFR was parallel with the changes of oxidative stress and inflammation when CKD developing.	25375354
Inflammation	Altered Intercellular Communication	The lack of relationship between fecal M2-PK and calprotectin suggests that contributing factor(s) other than inflammation may be present.	25376228
Acute inflammation	Altered Intercellular Communication	Postoperative ghrelin administration is safe and may suppress protracted postoperative inflammation in patients who undergo esophagectomies.	25377269
Inflammation, Peri-Implantitis	Altered Intercellular Communication	Lhe research also revealed high prevalence of obligate piriodontak pathogens in areas of inflammation during periimplantitis.	25377581
intraepithelial, Inflammation, Hyperemia	Altered Intercellular Communication	It was shown that adenoids of the patients with complicated chronic adenoiditis less frequently exhibit markers of active inflammation, such as hyperemia, intraepithelial infiltration, and hemosiderophages.	25377676
Inflammation, Abnormal cardiovascular function, Disorder of mineral metabolism	Altered Intercellular Communication	Our results suggest that patients undergoing MHD with severe CCC or AAC have high degree of mineral metabolism disorder, inflammation, and cardiovascular function disorder.	25377787
APP gene, Inflammation	Altered Intercellular Communication	Therefore, we hypothesized that the inflammasome is a key mediator of initial inflammation in AAA formation.	25378412
Alveolar damage, Respiratory Failure, Lymphopenia, Pneumonitis	Altered Intercellular Communication	Our findings suggest that H7N9 influenza virus induced an immunological response towards overt pulmonary inflammation and systemic lymphopenia which led to intense alveolar damage and respiratory failure.	25378539
Inflammation, respiratory	Altered Intercellular Communication	It is strongly associated with complications, principally respiratory sepsis, and systemic inflammation.	25379848
Primary malignant neoplasm, Chronic inflammation, Malignant Neoplasms	Altered Intercellular Communication	Cross-sectional studies show that the degree of the defect may be associated with risk in some types of cancer, especially cancers associated with chronic inflammation.	25379950
Inflammation, Hypoxia, Anemia, hepcidin	Altered Intercellular Communication	Hepcidin is a small defensin-like peptide whose production by hepatocytes is modulated in response to anemia, hypoxia, or inflammation.	25380934
Inflammation, Disease	Altered Intercellular Communication	However, analysis of clinical response data showed that patients achieving low disease activity or remission seem to have a protective lipid profile, suggesting that better control of inflammation and disease activity can affect lipid metabolism.	25381986
Inflammation	Altered Intercellular Communication	The available evidence indicates that high inflammation interferes with lipid metabolism, whereas good control of the chronic inflammatory state may positively influence the lipid profile and cardiovascular risk.	25381986
Necrotizing granulomatous inflammation, Takayasu Arteritis	Altered Intercellular Communication	Takayasu arteritis is caused by an autoimmune process that results in chronic granulomatous inflammation.	25383863
Inflammation, Retinal ischemia	Altered Intercellular Communication	Optical coherence tomography can be useful in detecting retinal ischemia and the degree of inflammation in Takayasu retinopathy especially at the early stage.	25383863
Communicable Diseases, Thrombocytopenia	Altered Intercellular Communication	Spontaneous heparin-induced thrombocytopenia syndrome without any proximate heparin exposure, infection, or inflammatory condition: Atypical clinical features with heparin-dependent platelet activating antibodies.	25383922
Inflammation, Blood Clot, Hypoxia	Altered Intercellular Communication	A large proportion of AAA develops an intraluminal thrombus, which contributes to hypoxia, inflammation and tissue degradation.	25384012
Tumor necrosis	Altered Intercellular Communication	Monocytes and dendritic cells (DC) produce tumour necrosis factor (TNF)a during inflammatory processes, but secrete interleukin (IL)-10 simultaneously in order to balance the pro-inflammation.	25384561
Inflammation, Hyperlipidemia, Plaque, Atherosclerotic, Obesity, Dental Plaque	Altered Intercellular Communication	We concluded that sP-selectin, induced by systemic inflammation in conditions including obesity and hyperlipidemia, promoted atherosclerotic plaque and neointimal formation, plaque rapture and neointimal bleeding, further leading to AMI.	25384966
Cholesteatoma, Inflammation	Altered Intercellular Communication	Cholesteatoma represents progressive expansion of the keratinizing squamous epithelium in the middle ear with subsequent chronic inflammation in subepithelial connective tissues.	25385222
Cholesteatoma, Inflammation, Necrosis	Altered Intercellular Communication	The data suggest that in cholesteatoma, HMGB1 released from stressed or necrotic epithelial cells and binding to RAGE overexpressed in keratinocytes initiates molecular signaling that culminates in pro-inflammatory cytokine release and chronic inflammation.	25385222
Inflammation, Haiti	Altered Intercellular Communication	There may be a compensatory expansion of Treg at the sites of inflammation in tissues of PTC with HT contributing to the immune response suppression.	25387566
Tissue damage, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	This finding provides a link among neutrophils, inflammation and tissue damage in diabetes.	25387570
Inflammation	Altered Intercellular Communication	Soluble urokinase plasminogen activator receptor (suPAR) is a highly sensitive marker that reflects increased inflammation and is positively correlated with pro-inflammatory biomarkers.	25387618
Inflammation	Altered Intercellular Communication	Our results underscore the importance of T lymphocytes during adipose tissue expansion, and the presence of potential compensatory mechanisms that may work to counteract adipose tissue inflammation, possibly through an increased number of T-regulatory cells.	25388403
Inflammation, Arthritis, Osteoporosis, Diabetes Mellitus	Altered Intercellular Communication	Compound A (CpdA), a selective glucocorticoid receptor agonist, reduces inflammation in murine arthritis models and does not induce diabetes or osteoporosis, thus offering an improved risk:benefit ratio in comparison with glucocorticoids.	25389358
Inflammation	Altered Intercellular Communication	Enhanced NO production increases the activities of the transcription factors p53 and nuclear factor kB (NF-kB) in several models of disease-associated inflammation.	25389371
Parkinson Disease, Inflammation, Muscular Atrophy	Altered Intercellular Communication	In rodent models of systemic inflammation, Parkinson's disease, or aging-related muscular atrophy, S-nitrosylation of SIRT1 correlated with increased acetylation of p53 and p65 and activation of p53 and NF-kB target genes, suggesting that S-nitrosylation of SIRT1 may represent a proinflammatory switch common to many diseases and aging.	25389371
Inflammation, Muscular Dystrophy, Duchenne, Doctor of Dental Medicine, muscle injury	Altered Intercellular Communication	In Duchenne muscular dystrophy (DMD), a genetic disruption of dystrophin protein expression results in repeated muscle injury and chronic inflammation.	25390038
Inflammation	Altered Intercellular Communication	Histology indicates that hyper-intense MRI foci correspond to areas of dystrophic lesions containing inflammation as well as regenerating, degenerating and hypertrophied myofibers.	25390038
Inflammation, Hypertrophy	Altered Intercellular Communication	In summary, we show that adipocyte hypertrophy is linked to increased inflammation in AT in obese children, thereby providing evidence that obesity-associated AT dysfunction develops in early childhood and is related to insulin resistance.	25392242
Inflammation	Altered Intercellular Communication	Complications in both groups were typically rare and self-limited, with recurrent inflammation being most common.	25393037
Inflammation, Obesity	Altered Intercellular Communication	Obesity, characterized by low-grade inflammation both in blood and white adipose tissue (WAT) is associated with increased C-reactive protein (CRP), a well-known acute phase protein.	25393045
Inflammation, AKAP4 protein, human	Altered Intercellular Communication	We also compared the same parameters after separating patients with "high" inflammation (HI, CRP>=20 mg/L, n=52) and with "low" inflammation (LI, CRP<20 mg/L, n=622).	25393045
Inflammation, Obesity	Altered Intercellular Communication	Our results suggest that WAT inflammation is a major contributor to increased CRP in obesity.	25393045
Nasopharyngeal carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Several inflammation-based prognostic scoring systems, including Glasgow Prognostic Score (GPS), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) have been reported to predict survival in many malignancies, whereas their role in metastatic nasopharyngeal carcinoma (NPC) remains unclear.	25393117
methyldopa, Inflammation	Altered Intercellular Communication	AMD is a multifactorial disorder but complement-mediated inflammation at the level of the retina plays a pivotal role.	25393287
Inflammation, Granulation finding	Altered Intercellular Communication	Microscopically, the lamina propria in all 12 cases contained inflammation and granulation tissue.	25393329
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	It is still controversial which cell types are responsible for synovial inflammation in osteoarthritic (OA) joints.	25393692
Inflammation, Pseudolymphoma	Altered Intercellular Communication	In the spleen, NIAM(m/m) mice had prominent white pulp expansion which correlated with enhanced increased reactive lymphoid hyperplasia and evidence of systemic inflammation.	25393878
Inflammation, Fatty degeneration	Altered Intercellular Communication	Inflammation and steatosis did not show any correlation with SWE values except for values from the left lobe, which showed correlation with steatosis (r = 0.24, P = .004).	25393946
Intraocular inflammation	Altered Intercellular Communication	Frequency and characteristics of intraocular inflammation after aflibercept injection.	25394166
Intraocular inflammation	Altered Intercellular Communication	To report the frequency and characteristics of intraocular inflammation after intravitreal aflibercept injection.	25394166
Intraocular inflammation	Altered Intercellular Communication	There were 28 cases of intraocular inflammation after a total of 5,905 aflibercept injections among 1,660 patients.	25394166
Inflammation, Critical Illness	Altered Intercellular Communication	Systemic inflammation often leads to complications in critically ill patients.	25394242
glycation, Damage, Inflammation	Altered Intercellular Communication	Activation of the receptor for advanced glycation end-products (RAGE) generates inflammatory cytokines, proteases, and oxidative stress and may link inflammation to subsequent organ damage.	25394242
Vasculitis, vascular inflammations	Altered Intercellular Communication	In contrast, patients with vascular inflammation detectable at imaging had higher PTX3 concentrations (P = 0.016) than those in which vessel inflammation was not evident, while CRP levels were similar.	25394473
Inflammation, Arteritis	Altered Intercellular Communication	These results support the contention that PTX3 reflects different aspects of inflammation than CRP and might represent a biomarker of actual arteritis in TA.	25394473
Dyspnea, Deglutition Disorders, Hyperostosis, Diffuse Idiopathic Skeletal	Altered Intercellular Communication	Progressive dysphagia and dyspnoea presenting after major neck trauma can occasionally be secondary to post-traumatic inflammation and mass effect associated with a calcified osteophytic anterior longitudinal ligament, a frequent finding in diffuse idiopathic skeletal hyperostosis, though rarely enough to cause such symptoms.	25394498
Inflammation, Peritonitis	Altered Intercellular Communication	Besides peritonitis, the most common complication, indicators of chronic inflammation are also present in patients treated by peritoneal dialysis.	25394528
Inflammation, Kidney Failure	Altered Intercellular Communication	There is an increased mortality risk in long-term hemodialysis patients of renal failure due to the chronic inflammation.	25394530
Cancer-related fatigue, Inflammation, Amyloidosis, MEFV gene	Altered Intercellular Communication	The current results indicate the germ-line mutations in both genetic biomarkers (MEFV and SAA1 genes) that are related to inflammation and amyloidosis processes may play a crucial role in CRF pathogenesis due to the long-term chronic inflammation.	25394530
Myelofibrosis, Chronic inflammation, Malignant Peripheral Nerve Sheath Tumor, Thrombocytosis, Polycythemia Vera	Altered Intercellular Communication	The Philadelphia-negative chronic myeloproliferative neoplasms - essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF) (MPNs) - have recently been shown to be associated with chronic inflammation, oxidative stress and accumulation of reactive oxygen species (ROS).	25397683
Gammopathy, Inflammation, Urticaria	Altered Intercellular Communication	The patients had chronic urticaria, IgM gammopathy and an elevation of the serum levels of inflammation markers.	25398167
Inflammation	Altered Intercellular Communication	Sonoelastography--a useful adjunct for parotid gland ultrasound assessment in patients suffering from chronic inflammation.	25398237
Sjogrens Syndrome", Inflammation, "Stensens duct", PEELING SKIN SYNDROME	Altered Intercellular Communication	Prospective analysis included 78 consecutive patients with parotid gland pathology: sialolithiasis (33), Stensen's duct stenosis (15), chronic inflammation (10), and primary Sjogren syndrome (pSS) (20) treated at the Department of Otolaryngology, Head and Neck Surgery of PUMS.	25398237
Inflammation, "Stensens duct	Altered Intercellular Communication	Mean elasticity values for pSS (111 Kilopascals (kPa), Stensen's duct stenosis (63 kPa), sialolithiasis (82 kPa), and chronic inflammation (77 kPa) were significantly higher than the mean value for healthy patients (24 kPa).	25398237
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In pSS the parenchyma was almost twice as stiff as in chronic inflammation (p=0.02), although subjective complaints were mostly mild or moderate, and the ultrasonographic picture did not present features of fibrosis.	25398237
Inflammation	Altered Intercellular Communication	Sonoelastography, by improving routine ultrasonographic assessment, might be a useful tool for parotid evaluations during the course of chronic inflammation.	25398237
Inflammation	Altered Intercellular Communication	Sputum induction is a non-invasive method for obtaining measurements of inflammation in the airways.	25398249
Inflammation, Liver Failure	Altered Intercellular Communication	Steroid treatment might be an option to prevent progress of life-threatening liver failure and liver transplantation in patients with hepatitis E-induced acute liver injury and high-grade inflammation.	25398314
Inflammation	Altered Intercellular Communication	No overall changes were observed in synovial inflammation score or the presence of T cells, B cells or macrophages.	25398374
Symptoms, Inflammation, Dryness of eye	Altered Intercellular Communication	These findings indicate that oxidative stress is associated with dry eye and that hyaluronic acid/vitamin B12 eye drops may attenuate oxidative stress and inflammation, improving dry eye symptoms.	25398660
Gingivitis	Altered Intercellular Communication	Moreover, the mean gingival index was 1.68+-0.31, which indicates a moderate gingival inflammation.	25399215
Inflammation	Altered Intercellular Communication	In fact, males showed more severe signs of gingival inflammation compared with females (p=0.001).	25399215
Inflammation, Dental Plaque	Altered Intercellular Communication	Interestingly, the age was not related either to the gingival inflammation (p=0.13), or to the amount of plaque accumulation (p=0.17).	25399215
Osteolysis	Altered Intercellular Communication	Genetic variation within inflammatory signaling and bone turnover pathways may play a role in susceptibility to osteolysis.	25399506
Inflammation, Mild cognitive disorder, millicurie, Data types - Address	Altered Intercellular Communication	Positron emission tomography studies detected Ab deposition and inflammation in the brains of subjects with amnestic mild cognitive impairment (MCI) before the onset of AD.	25399811
Inflammation, Data types - Address	Altered Intercellular Communication	Given the role of a7 nAChR in Ab deposition and inflammation, tropisetron represents an attractive potential therapeutic drug to delay or prevent MCI and AD.	25399811
Inflammation, Prostate carcinoma	Altered Intercellular Communication	The possible relationship of inflammation derived from dietary exposures with prostate cancer risk has not been investigated.	25400225
Inflammation, Dermatologic disorders, Dermatitis	Altered Intercellular Communication	Bullous pemphigoid (BP) and dermatitis herpetiformis (DH) are skin diseases associated with inflammation.	25400334
Tissue damage, Inflammation	Altered Intercellular Communication	Mast cells may play an essential role in activating inflammation, which ultimately contributes to the tissue damage observed in BP and DH.	25400334
Communicable Diseases, Hemorrhage, Inflammation	Altered Intercellular Communication	No bleeding, inflammation or infection occurred in these patients.	25400740
Inflammation	Altered Intercellular Communication	TLR4 and TLR9 show significant correlation with the severity of inflammation.	25400780
Inflammation, Stomach Carcinoma, Gastritis	Altered Intercellular Communication	In superficial gastritis and atrophy/intestinal metaplasia the inflammation was predominately mediated by TLR4, while in gastric cancer the inflammation was mainly mediated by TLR9.	25400780
UBC protein, human, Inflammation	Altered Intercellular Communication	The patients enrolled in the study were both oncological patients with UBC and non-oncological patients with inflammation (14 patients).	25400813
Virus Diseases	Altered Intercellular Communication	Innate immunity to viral infection involves induction of the type I IFN response; however, dysfunctional regulation of this pathway leads to inappropriate inflammation.	25401470
Inflammation, Uveitis	Altered Intercellular Communication	Uveitis, or inflammation of the uveal tract (i.e., iris, ciliary body, and choroid), results from a heterogeneous collection of disorders of varying etiologies and pathogenic mechanisms.	25403035
Inflammation, melanoma	Altered Intercellular Communication	25-Hydroxyvitamin D2 /D3 levels and factors associated with systemic inflammation and melanoma survival in the Leeds Melanoma Cohort.	25403087
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The Global Initiative defines COPD for chronic obstructive lung disease as an entirely preventable and treatable disease characterized by sputum production, bacterial colonisation, neutrophilic bronchial airway inflammation and poor health status.	25403149
Inflammation, Primary malignant neoplasm, Carcinoma of lung, Carcinogenesis	Altered Intercellular Communication	The present results indicate that associations of vitamin B6 with cancer may be related to increased catabolism of vitamin B6, in particular for lung cancer where inflammation may be largely involved in carcinogenesis.	25404109
Inflammation, Dysplasia, Primary malignant neoplasm, Thrombopoietin Receptor Agonist LGD-4665, HGD gene	Altered Intercellular Communication	The cases were divided into different groups according to the pathological diagnosis of normal bronchial mucosa, inflammation, low-grade dysplasia (LGD), high-grade dysplasia (HGD), and invasive cancer.	25404270
Inflammation, Primary malignant neoplasm, Thrombopoietin Receptor Agonist LGD-4665	Altered Intercellular Communication	The Y values were different and statistically different between invasive cancer and LGD (P<0.001) and invasive cancer and inflammation (P=0.040), respectively.	25404270
Inflammation, Primary malignant neoplasm, Thrombopoietin Receptor Agonist LGD-4665	Altered Intercellular Communication	Similarly, the V values between invasive cancer and LGD and inflammation and normal bronchial mucosa were different.	25404270
Inflammation, HGD gene	Altered Intercellular Communication	Lastly, the V values between normal bronchial mucosa and HGD and inflammation and normal bronchial mucosa were different.	25404270
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Strategies to mitigate age-dependent dysregulation in glycemia should therefore target systemic and/or local inflammation and fibrosis of the aged islet vasculature.	25404292
Systemic Inflammatory Response Syndrome, Pneumonia	Altered Intercellular Communication	Decreased TLR-2 expression was associated with the occurrence of SIRS and pneumonia, suggesting a role in the cause of postoperative inflammatory conditions.	25405275
Inflammation, Parasitic Diseases	Altered Intercellular Communication	Anthropometry, hemoglobin, serum ferritin, transferrin receptors, retinol-binding protein and zinc concentrations, inflammation status, urinary iodine concentration and parasite infection were measured.	25405764
Inflammation, Anemia, Sickle Cell	Altered Intercellular Communication	Here, we evaluate Epo level vs. renal function, oxygenation, and markers of inflammation for patients treated for sickle cell disease at our institution.	25405915
Inflammation, Hemolysis (biological function)	Altered Intercellular Communication	Higher Epo levels were seen in patients receiving hydroxyurea (HU), but no correlation with oxygenation, hemolysis, renal function, or inflammation was observed.	25405915
Inflammation, Peri-Implantitis	Altered Intercellular Communication	The levels of typical bone matrix molecules, including SPP1, BGLAP, and COL9A1, in patients with peri-implantitis were reduced, while the inflammation marker interleukin 8 (IL8) was highly expressed.	25406169
Autoinflammatory Syndrome, Inflammation, Pancreatitis, Bacterial sepsis, Gout, Candidemia, Infectious Mononucleosis, Infection, Rheumatoid Arthritis, Endotoxemia, Crohn Disease, Respiratory Tract Infections	Altered Intercellular Communication	The release of sTLR2 and sTLR4 was studied in in-vitro stimulations, as well as in-vivo during experimental human endotoxemia (n = 11, 2 ng/kg LPS), and in plasma of 394 patients with infections (infectious mononucleosis, measles, respiratory tract infections, bacterial sepsis and candidemia) or non-infectious inflammation (Crohn's disease, gout, rheumatoid arthritis, autoinflammatory syndromes and pancreatitis).	25406630
Communicable Diseases, Inflammation	Altered Intercellular Communication	sTLR4 had a similar area under the ROC curve [AUC] for differentiating infectious and non-infectious inflammation compared to CRP: 0.72 (95% CI 0.66-0.79) versus 0.74 (95% CI 0.69-0.80) [P = 0.80], while sTLR2 had a lower AUC: 0.60 (95% CI 0.54-0.66) [P = 0.0004].	25406630
Sepsis, Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Activation of inflammation and coagulation was closely related and mutually interdependent in sepsis.	25407675
Inflammation, Diabetic Retinopathy	Altered Intercellular Communication	Circulating markers of inflammation and endothelial function, and their relationship to diabetic retinopathy.	25407692
Inflammation, Diabetic Retinopathy	Altered Intercellular Communication	To examine the relationships of serum markers of inflammation and endothelial function to diabetic retinopathy.	25407692
Inflammation, Obesity, Abdominal, Metabolic Syndrome X, ETV3 wt Allele, Glucose Intolerance (disease), Ventricular Dysfunction	Altered Intercellular Communication	Growing evidence demonstrates subtle left ventricular myocardial dysfunction in patients with metabolic syndrome (MetS), with central obesity, glucose intolerance and inflammation emerging as important contributors.	25407698
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Biological markers of MetS and inflammation as well as RV GLS (-21.8 +- 3.8 vs -24.3 +- 3.0%, P = 0.009) and systolic (P = 0.003) and early diastolic (P = 0.01) SR, but not TDI indexes, significantly improved after diet and exercise training, and vector velocity imaging data in MetS following the lifestyle intervention no longer differed from controls.	25407698
Hyperglycemia, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	In type 2 diabetes, acute hyperglycemia worsens endothelial function and inflammation,while resistance to GLP-1 action occurs.	25407792
Inflammation, Data types - Address	Altered Intercellular Communication	The crucial step in AD pathogenesis is the production of amyloid-b42 peptide, which causes chronic inflammation.	25408215
Abdominal Pain	Altered Intercellular Communication	Here we present a rare case of a 9 year old girl referred by her general practitioner due to severe right lower quadrant abdominal pain with a presumed diagnosis of acute appendiceal inflammation.	25408729
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Exacerbation	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) exacerbations are acute events of worsened respiratory symptoms and enhanced inflammation partly mediated by NF-kB activation.	25409035
ARCN1 gene, Inflammation	Altered Intercellular Communication	RelB, an NF-kB family member, suppresses cigarette smoke-induced inflammation but its expression in COPD is unknown.	25409035
Inflammation, Neoplasms	Altered Intercellular Communication	The platelet count, as an inflammation marker, is involved in the progress of tumor invasion.	25409616
Inflammation	Altered Intercellular Communication	We propose that low levels of haCBG in chronic inflammation may limit the availability of cortisol to inflammatory sites, perpetuating the inflammatory process.	25409953
Granulomatous inflammation	Altered Intercellular Communication	Imaging demonstrated an invasive process and a biopsy was taken, which showed granulomatous inflammation that stained positively for mycobacteria.	25410031
Refractory anemias, Rheumatoid Arthritis, Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Taking autoimmune inflammation of rheumatoid arthritis as entry point, this paper discussed the clinical effect of horsetail mixture on rheumatoid arthritis (RA) and its mechanism.	25410066
Lupus Erythematosus, Discoid	Altered Intercellular Communication	Discoid lupus erythematosus may lead to significant orbital inflammation syndrome.	25410119
Inflammation, Lupus Erythematosus, Discoid	Altered Intercellular Communication	Ocular manifestations related to discoid lupus erythematosus are uncommon and few cases of eye inflammation are reported.	25410119
Inflammation	Altered Intercellular Communication	Inflammation may contribute to the pathophysiology underlying impaired bone metabolism.	25410434
Inflammation, Hemorrhage, Condylomata Acuminata, High-Grade Squamous Intraepithelial Lesions, Trichomonas Vaginitis	Altered Intercellular Communication	Risk factors for HSIL included being in age group of 46-55 years (adjusted odds ratio [aOR] = 1.15, 95% CI: 1.07-1.44, compared with the 25-35 age group), bleeding after intercourse (aOR = 2.08, 95% CI: 1.40-3.10), and presence of trichomonas vaginalis infection (aOR = 2.62, 95% CI: 1.35-5.07), cervical inflammation (aOR = 4.22, 95% CI: 3.39-5.26), and genital warts (aOR = 3.89, 95% CI: 2.54-7.70).	25410572
Hemorrhage, Condylomata Acuminata, High-Grade Squamous Intraepithelial Lesions, Trichomonas Vaginitis, Uterine Cervicitis	Altered Intercellular Communication	Women aged 46-55 years, those with a lower education level, those reporting bleeding after intercourse, and those affected by Trichomonas vaginalis infection, cervical inflammation and genital warts are at higher risk for HSIL.	25410572
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Peroxisome proliferator-activated receptor-g (PPARg) was implicated in several pathological conditions including diabetes and inflammation.	25410618
Deficiency of micronutrients, Malaria, Inflammation	Altered Intercellular Communication	Adjusting indicators of iron and vitamin A status based only on APP may inaccurately estimate the prevalence of micronutrient deficiencies in settings with a high prevalence of malaria and inflammation.	25411038
Crohn Disease, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Multiple micronutrient (MN) deficiency morphologically mimics EE, and o-3 (n-3) polyunsaturated fatty acids reduce mucosal inflammation in Crohn disease.	25411039
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Increased plasma DPP4 activity predicts new-onset hypertension in Chinese over a 4-year period: possible associations with inflammation and oxidative stress.	25411054
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	This finding may have important implications for understanding the effects of DPP4 in promoting inflammation and oxidative stress in the pathogenesis of hypertension.	25411054
palladium, Inflammation, Degenerative disorder	Altered Intercellular Communication	Central to this is the knowledge that inflammation is a known hallmark of PD and of many other degenerative diseases.	25411230
Inflammation, Fibrosis Assessment, Diabetes Mellitus, Hypertension, CTCAE, Chronic Kidney Diseases	Altered Intercellular Communication	Uncontrolled diabetes, inflammation, and hypertension are key contributors to progressive renal fibrosis and subsequent loss of renal function.	25411467
Inflammation, Aortic Aneurysm, atherosclerotic, Atherosclerosis	Altered Intercellular Communication	Unlike adults, in whom atherosclerosis, inflammation, and advanced age are typically contributing factors, aortic dissection in children is usually due to nonatherosclerotic causes.Aortic aneurysms can be asymptomatic when small but, when significantly enlarged, can compromise organ function and dissect, resulting in high mortality rates.	25411855
Necrotizing granulomatous inflammation, Sarcoidosis, Systemic disease, Obesity, Overweight	Altered Intercellular Communication	Sarcoidosis, a systemic disorder characterized by chronic granulomatous inflammation, occurs more frequently among US black women, as do overweight and obesity.	25411869
Inflammation, Sarcoidosis, Overweight, Obesity	Altered Intercellular Communication	Little is known about the relation of overweight and obesity, which induce chronic inflammation, to incidence of sarcoidosis.	25411869
Inflammation	Altered Intercellular Communication	Xanthogranulomatous inflammation (XGI) is a rare chronic inflammatory condition most commonly involving the kidneys and gallbladder.	25412596
Inflammation	Altered Intercellular Communication	Xanthogranulomatous inflammation (XGI) is a rare chronic inflammatory condition most commonly involving the kidneys and gallbladder.	25412596
Inflammation, Coronary Stenosis, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Multiple inflammatory pathways influence plaque stability, but direct assessment of endothelial inflammation at the site of coronary artery stenosis has largely been limited to pathology samples or animal models of atherosclerosis.	25413339
vascular inflammations, Electrocardiogram: myocardial infarction (finding), Dental Plaque	Altered Intercellular Communication	We conclude that increased VCAM-1 expression on EC and formation of EMP at the site of coronary plaque is positively correlated with the extent of vascular inflammation in patients with myocardial infarction.	25413339
Inflammation, Brucellosis, Lupus Erythematosus, Systemic, Lupus Erythematosus	Altered Intercellular Communication	Familial Mediterranean fever gene (MEFV) mutations and disease severity in systemic lupus erythematosus (SLE): implications for the role of the E148Q MEFV allele in inflammation.	25413357
Inflammation, Lupus Nephritis	Altered Intercellular Communication	In this regard, absence of the E148Q mutation in SLE nephritis may serve as a clue for further investigation into its role as a general modulatory polymorphism for inflammation.	25413357
Dermatitis, Atopic, Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Open-angle glaucoma associated with severe atopic dermatitis (atopic glaucoma) tends to be severe and difficult to treat because of ocular surface/eye lid inflammation.	25415644
Inflammation, atherosclerotic	Altered Intercellular Communication	Stable phase post-MI patients have elevated VEGF levels correlated with inflammation markers, but not with atherosclerotic burden.	25417001
Inflammation, atherosclerotic	Altered Intercellular Communication	Furthermore, we investigated whether the values of VEGF correlate to either inflammation markers or the atherosclerotic burden.	25417001
Inflammation, atherosclerotic	Altered Intercellular Communication	We found that plasma levels of VEGF are increased in the stable phase after MI and correlate with inflammation cytokines, but not with the atherosclerotic burden.	25417001
Enteritis	Altered Intercellular Communication	MRE images were reviewed for presence of intestinal wall inflammation.	25417129
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Inflammation and cardiovascular risk assessment in Moroccan obese patients with and without metabolic syndrome: importance of lipoproteins ratios.	25417430
Inflammation, Cardiovascular Diseases, Obesity, Atherosclerosis	Altered Intercellular Communication	Inflammation, reported as a link between obesity and cardiovascular disease, contributes to the development of atherosclerosis.	25417430
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	In patients with MetS, lipoprotein profile alterations and low-grade inflammation were observed.	25417430
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Our study shows that Moroccan obese adults with MetS have altered lipoproteins profiles and suffer from low-grade inflammation.	25417430
Inflammation, Myocardial	Altered Intercellular Communication	Myocardial edema indicating acute inflammation was seen in one (14.3%) patient.	25417517
Inflammation	Altered Intercellular Communication	This may represent inflammation and a change in airway integrity, rather than increased secretion of this peptide.	25417673
Hypokalemia, Inflammation, Esophagitis, Toxic effect	Altered Intercellular Communication	Dose-limiting toxicities (Grade 2 esophagitis; Grade 3 aspartate aminotransferase increased, mucosal inflammation and hypokalemia) were reported at starting dose (1.5 mg trametinib/50 mg afuresertib once daily continuously), exceeding the MTD.	25417902
Fibrosis Assessment, Cardiovascular system	Altered Intercellular Communication	Galectin-3 is a marker of myocardial fibrosis and mediates aldosterone-induced cardiovascular inflammation and fibrosis.	25418979
Chronic lymphocytic inflammation, Pontine structure	Altered Intercellular Communication	Case 212: chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids.	25420171
Inflammatory abnormality of the eye	Altered Intercellular Communication	Gene delivery of a viral anti-inflammatory protein to combat ocular inflammation.	25420215
methyldopa, Diabetic Retinopathy, Disease, Uveitis	Altered Intercellular Communication	Inflammation of the retina is a contributing factor in ocular diseases such as uveitis, diabetic retinopathy, and age-related macular degeneration (AMD).	25420215
Autoimmune Diseases, Inflammation, Systemic Vasculitis, Granulomatosis	Altered Intercellular Communication	Granulomatosis with polyangiitis (GPA or Wegener) is a systemic autoimmune disease with inflammation of small- and medium-size vessels.	25420293
Erythema, Orchitis	Altered Intercellular Communication	Then he experienced bilateral auricular inflammation and painful erythema of the ankle.	25420560
Granulomatous inflammation	Altered Intercellular Communication	Pathological findings of the meninges in WG has been reported to be granulomatous inflammation.	25420562
Inflammation, Psoriasis	Altered Intercellular Communication	The elevation of plasma YKL-40 in psoriasis can be associated not only with inflammation of the disease, but also with ED.	25421412
Allergic sensitization, Airway structure	Altered Intercellular Communication	We screened for risk factors from children's and their families' histories, and assessed the usefulness of common markers of allergic sensitisation of the airway as surrogates for airway inflammation and increased risk for adverse respiratory events.	25421587
Inflammation, Demyelination, Nerve Degeneration	Altered Intercellular Communication	Demyelination and neurodegeneration of cortical grey matter contribute to a more severe disease, and inflammation of the forebrain meninges associates with pathology of the underlying neocortical grey matter, particularly in deep sulci.	25421634
Demyelination, Arachnoiditis, Meningitis	Altered Intercellular Communication	We assessed the extent of meningeal inflammation of the cerebellum, another structure with a deeply folded anatomy, to better understand the association between subarachnoid inflammation and grey matter pathology in progressive MS. We examined demyelinating and neuronal pathology in the context of meningeal inflammation in cerebellar tissue blocks from a cohort of 27 progressive MS cases previously characterized on the basis of the absence/presence of lymphoid-like aggregates in the forebrain meninges, in comparison with 11 non-neurological controls.	25421634
Demyelination, Meningitis	Altered Intercellular Communication	Demyelination and meningeal inflammation of the cerebellum was greatest in those cases previously characterized as harbouring lymphoid-like structures in the forebrain regions.	25421634
Meningitis	Altered Intercellular Communication	Meningeal inflammation was mild to moderate in cerebellar tissue blocks, and no lymphoid-like structures were seen.	25421634
Inflammation	Altered Intercellular Communication	These data suggest that chronic inflammation is widespread throughout the subarachnoid space and contributes to a more severe subpial demyelinating pathology in the cerebellum.	25421634
Lymphohistiocytosis, Hemophagocytic, Acute inflammation, Chronic granulomatous disease	Altered Intercellular Communication	Infection-triggered hemophagocytic lymphohistiocytosis (HLH), which manifests itself as pathologic hyperactive inflammation, has been observed in subjects with CGD.	25422023
Science of Etiology, Acute inflammation	Altered Intercellular Communication	The initial diagnostic evaluation demonstrated pathologic hyperactive inflammation, meeting the HLH-2004 diagnostic criteria without an identified infectious etiology.	25422023
Immunologic Deficiency Syndromes, Communicable Diseases, Lymphohistiocytosis, Hemophagocytic, Acute inflammation	Altered Intercellular Communication	It serves as a reminder that both immunodeficiency and inflammatory disorders may share features of pathologic hyperactive inflammation and highlights the conundrum that clinicians face when treating HLH in the setting of an unresolved infection.	25422023
Adult Non-Hodgkin Lymphoma	Altered Intercellular Communication	Polymorphic variation of inflammation-related genes and risk of non-Hodgkin lymphoma for Uygur and Han Chinese in Xinjiang.	25422198
Adult Non-Hodgkin Lymphoma, RTEL1 gene	Altered Intercellular Communication	Polymorphisms of inflammation-related genes have been found to be associated with non-Hodgkin lymphoma (NHL) or some of its subtypes, but only a few relevant data have been reported in China.	25422198
RTEL1 gene	Altered Intercellular Communication	Our results showed that polymorphic variations of inflammation-related genes could be important to the NHL etiology of the Han population, and that these may only have limited influence on the Uygur population.	25422198
Granulomatous, Chronic inflammation, Necrotizing, Ulcer	Altered Intercellular Communication	Two biopsies of the ulcer were taken and reported as granulomatous, necrotising, with chronic inflammation (first), and as hyperplasic epidermis with linfocitary infiltrate and the presence of plenty of plasmatic cells (second).	25422341
Inflammation	Altered Intercellular Communication	Toll-like receptors (TLRs) are damage-associated molecular patterns receptors, which are essential in the activation of the inflammasome cascade, required for the initiation of inflammation.	25423559
Inflammation, Erythema	Altered Intercellular Communication	Deep erythema and inflammation after re-epithelialization of superficial wounds is a sign of scar formation.	25424054
Inflammation	Altered Intercellular Communication	Corticosteroids may prevent scarring by suppression of inflammation and fibroblast activity.	25424054
Inflammation, Pancreatitis, Pain Distress Question, Fibrosis Assessment, Exocrine pancreatic insufficiency, Atrophic	Altered Intercellular Communication	Chronic pancreatitis is characterized by inflammation, atrophy, fibrosis with progressive ductal changes, and functional changes that include variable exocrine and endocrine insufficiency and multiple patterns of pain.	25424572
Gastrointestinal tract structure	Altered Intercellular Communication	We investigated HIF-1a expression in chronic ischemic and inflammatory conditions of the human gastrointestinal (GI) tract.	25425478
Synovitis, Edema of bone marrow, Skin lesion, Orchitis, Tenosynovitis	Altered Intercellular Communication	We determined the apparent improvement of synovitis, periarticular inflammation, tenosynovitis and/or bone marrow edema by MRI after anti-TNF-a treatments in all the patients together with the improvement of skin lesions.	25425546
Inflammation, Vegetation, Necrosis, Bacterial Endocarditis	Altered Intercellular Communication	Of 47 patients, 33 (70.2%) had either very small or no vegetations but had focal necrosis and inflammation of valve tissue that supported the diagnosis of infective endocarditis.	25425980
Pancreatitis	Altered Intercellular Communication	The interleukin (IL)-23/IL-17 axis plays an important role in various inflammatory conditions but its function in acute pancreatitis (AP) is not well understood.	25426616
Inflammation, Chronic Periodontitis	Altered Intercellular Communication	The prevalence of gingival inflammation was 86%, and nearly 7% of the adolescents had chronic periodontitis.	25427260
Inflammation, Calculi	Altered Intercellular Communication	The prevalence of gingival inflammation was high, and both the debris and calculus levels were strongly associated with gingival status in these adolescents.	25427260
Periodontitis	Altered Intercellular Communication	Increased C-reactive protein levels have been found in all active inflammations, including periodontitis.	25427270
Inflammation, Periodontitis	Altered Intercellular Communication	Two-week treatment with a 0.1% chlorhexidine mouthwash slightly reduced the gingival inflammation associated with periodontitis.	25427325
Inflammation, GYPB gene, Sweet Syndrome	Altered Intercellular Communication	Sweet syndrome (SS) is a relatively rare pediatric diagnosis, with fewer than 80 pediatric cases reported in the literature, characterized by tender erythematous plaques and nodules associated with systemic inflammation.	25427755
Inflammation, Fever, CTCAE	Altered Intercellular Communication	All had fever, elevated markers of systemic inflammation, and typical skin lesions.	25427755
Inflammation, Observation Method - Coagulation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	The results suggest that levels of plasma TF and interleukin 18 are significantly increased in patients with ACS, and there is significant correlation between the two, indicating an interaction between inflammation and coagulation in patients with ACS and an important role of these two in the occurrence and development of such disease.	25427791
Cardiovascular morbidity, Inflammation, Obesity	Altered Intercellular Communication	Obesity is associated with increased cardiovascular morbidity and mortality, inflammation, and elevated cortisol levels.	25429009
Acute lymphocytic leukemia, Arteritis	Altered Intercellular Communication	Changes of sulfur dioxide, nuclear factor-kB, and interleukin-8 levels in pediatric acute lymphoblastic leukemia with bacterial inflammation.	25430458
Inflammation, leukemia, Gas Gangrene	Altered Intercellular Communication	Bacterial inflammation is a common complication in patients with leukemia, and sulfur dioxide (SO2) is a bioactive molecule in modulating Gram-negative bacilli infection.	25430458
Inflammation	Altered Intercellular Communication	SO2 may play an anti-inflammatory role during the process of inflammation by inhibiting the activation and transcription of NF-kB.	25430458
Inflammation, Vegetation	Altered Intercellular Communication	Moreover, in the absence of vegetations, detection of delayed enhancement representing endothelial inflammation of the cardiovascular structures can contribute to the diagnosis and treatment planning of IE.	25430531
Inflammation, Left ventricular systolic dysfunction, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	This study evaluated the relationship between physical activity status and the development of left ventricular systolic dysfunction (LVSD) according to inflammation and sex in elderly patients who had had an ACS.	25432196
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Osteoarthritis (OA) is defined by signs and symptoms of inflammation within the affected joint.	25432384
Inflammation, Renal cyst	Altered Intercellular Communication	Computed tomography findings were consistent with complex renal cysts and perilesional inflammation.	25433426
Inflammation, Fibromyalgia, Hepatobiliary Disorder, Abdominal Pain, Chronic liver disease	Altered Intercellular Communication	If abdominal pain was included in the model, etiology became nonsignificant, indicating that it may be central sensitization due to abdominal pain in patients with chronic liver disease that explains fibromyalgia symptoms rather than the etiology of liver disease or inflammation.	25433921
Necrosis, Fibrosis Assessment, Inflammatory disorder, Waldenstrom Macroglobulinemia, Retractile Mesenteritis	Altered Intercellular Communication	Sclerosing mesenteritis (SM) is a rare, benign inflammatory disorder of unknown etiology, affecting the membranes of the digestive tract that involves lymphoplasmacytic inflammation, fat necrosis, and fibrosis of the mesentery.	25434322
Dysplasia, Parakeratosis, Autofluorescence, Inflammatory disease of mucous membrane	Altered Intercellular Communication	We found no dysplasia, which emphasises that autofluorescence detects non-dysplastic lesions caused by mucosal inflammation and parakeratosis.	25434724
Reproductive dehiscence, Inflammation, Neoplasms, Communicable Diseases, Coma, Post-Head Injury, Lipoma, Myositis Ossificans, Aspects of congenital malformations, Hemangioendothelioma, Hemangioma, Malignant Neoplasms, Vascular anomaly	Altered Intercellular Communication	Final diagnoses were formally established through simple standard clinical and radiological evaluation in 19 patients (11.8%; benign tumors, seven patients; malformations, eight patients; post-traumatic lesions, two patients; infection and inflammation, one patient each); ultrasound exam in five patients (3.1%; hemangioendotheliomas, two patients, fascial dehiscence, hemangioma, and vascular malformation, one patient each); MRI in four patients (2.5%; three vascular malformations and one lipoma); CT in two cases (1.2%; vascular malformation and myositis ossificans), and radiological examinations associated with cell aspiration in 15 cases (9.3%; ten benign tumors and five malignant tumors).	25435271
Inflammation, Ischemia	Altered Intercellular Communication	Our data seems to support the role of chronic inflammation and ischemia in the development of RVO.	25435748
Inflammation, Obesity	Altered Intercellular Communication	Taken together, these results confirm the previously established notion of chronic low grade inflammation in obesity and further suggests a role for the LT pathway in obesity-associated development of insulin resistance in humans.	25437865
Inflammation, Osteoporosis, Cardiovascular Diseases	Altered Intercellular Communication	Osteoporosis and cardiovascular disease may share common biological pathways, with inflammation playing a role in the development of both.	25437881
Inflammation, Diabetes Mellitus, Insulin-Dependent	Altered Intercellular Communication	Inflammation in childhood type 1 diabetes; influence of glycemic control.	25437887
Diabetes Mellitus, Insulin-Dependent, Inflammation, Cardiovascular Diseases, Atherosclerosis	Altered Intercellular Communication	Patients with type 1 diabetes have increased mortality from cardiovascular disease, and inflammation is important in the development of atherosclerosis.	25437887
Inflammation, Atherosclerosis, Diabetes Mellitus	Altered Intercellular Communication	Our aim was to evaluate the extent of inflammation and the influence of glycemic control in the early phases of atherosclerosis in childhood type 1 diabetes.	25437887
Inflammation, Diabetes Mellitus, Insulin-Dependent, Hyperglycemia, Atherosclerosis	Altered Intercellular Communication	Our results indicate that inflammation may play an important role in the accelerated atherosclerosis in early type 1 diabetes, and that this process seems primarily driven by hyperglycemia.	25437887
Inflammation	Altered Intercellular Communication	To examine if overall diet quality is associated with cellular and soluble biomarkers of systemic inflammation in middle-aged individuals.	25437888
Inflammation, Primary malignant neoplasm, Cardiovascular Diseases	Altered Intercellular Communication	As the incidence of cardiovascular disease and cancer is directly correlated with the levels of inflammation, our findings might indicate a protective role of high-quality diet.	25437888
Inflammation, Sleep Apnea, Obstructive, Ischemic stroke	Altered Intercellular Communication	Association of inflammation and oxidative stress with obstructive sleep apnea in ischemic stroke patients.	25439077
Inflammation, "Reinkes edema	Altered Intercellular Communication	Cyclic tensile strain on vocal fold fibroblasts inhibits cigarette smoke-induced inflammation: implications for Reinke edema.	25439508
Reinkes edema", Carcinoma, Carpal Tunnel Syndrome, Inflammation	Altered Intercellular Communication	Our results demonstrate that Reinke edema patients have more extrovert personality characteristics in comparison to carcinoma patients and, importantly, CTS attenuates CSC-induced inflammation in HVFF.	25439508
Inflammation, Uveitis	Altered Intercellular Communication	In 19 nonglaucomatous, uveitic eyes with active inflammation, mean global and all sectoral RNFL measurements were greater than the normative 95th percentile.	25439601
Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is a chronic inflammatory condition.	25440769
Inflammation, Endothelial dysfunction, Pulmonary Hypertension	Altered Intercellular Communication	Chronic exposure to biomass fuel smoke has been implicated in the development of pulmonary hypertension and right ventricular pressure/volume overload through activation of inflammation, increase in vascular resistance, and endothelial dysfunction.	25440802
Inflammation, Female Genital Diseases, Unknown (origin) (qualifier value), Communicable Diseases, Fecal Impaction, nervous system disorder	Altered Intercellular Communication	Causes of urinary retention were mechanical obstruction in 14 patients (25%), infection or inflammation in 10 (18%), fecal impaction in 7 (13%), neurologic disorders in 6 (11%), gynecologic disorders in 4 (7%), and behavioral processes in 3 patients (5%); 12 patients (21%) were idiopathic.	25440826
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The aim of this study was to determine the association between iron parameters and inflammation in obese individuals with and without type 2 diabetes mellitus (T2DM).	25441587
Inflammation, Polymorphonuclear Cell Infiltrate, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis and vascular remodeling after injury are driven by inflammation and mononuclear cell infiltration.	25441669
Inflammation, Malnutrition, HD Term Type, Arterial Occlusive Diseases, CLU protein, human	Altered Intercellular Communication	Malnutrition or chronic inflammation was associated with poor outcome in HD patients with CLI due to infrapopliteal occlusive disease.	25441673
Allergic asthma, Inflammation	Altered Intercellular Communication	Allergic asthma is characterized by inflammation and airway remodeling.	25443138
Nonalcoholic Steatohepatitis, Inflammation	Altered Intercellular Communication	The indole derivative NecroX-7 improves nonalcoholic steatohepatitis in ob/ob mice through suppression of mitochondrial ROS/RNS and inflammation.	25443620
Post-Traumatic Stress Disorder, Trauma, Nervous System	Altered Intercellular Communication	Heavy drinking in PTSD is associated with partially neutralized neurotransmitter imbalance, but also with neuronal injury commonly observed in AUD.	25444536
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Inflammation is essential for the progression of fibrosis.	25445207
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	The urokinase plasminogen activator and its receptor have been associated with hepatic inflammation and fibrosis in mice.	25445207
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	High serum concentrations of soluble urokinase plasminogen activator receptor (suPAR) are suggested to be involved in inflammation, tissue remodeling, and cancer metastasis.	25445207
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	suPAR levels were associated with the severity of fibrosis, particularly in NAFLD, but did not correlate with inflammation.	25445207
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	However, this is the first study to investigate suPAR as a biomarker in NAFLD, and the results indicate that suPAR may constitute a severity marker related to fibrosis and prognosis rather than reflecting inflammation.	25445207
Inflammation	Altered Intercellular Communication	Pulmonary colonization with periopathogens seems to be associated with increased local inflammation.	25445885
Inflammatory Bowel Diseases, Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Inflammation plays a critical role in the pathophysiology of both inflammatory bowel disease and acute coronary syndrome.	25446295
Inflammation, Frailty, Cardiovascular Diseases	Altered Intercellular Communication	Frailty, geriatric conditions, cardiovascular diseases and WBC count have also been associated with low grade inflammation.	25446500
Inflammation, Disease	Altered Intercellular Communication	In this study, we observed that differential and total WBC counts do not seem to be associated with geriatric conditions but with CV diseases, low-grade inflammation and telomere length.	25446500
Inflammation, Tumor necrosis	Altered Intercellular Communication	Mucosal inflammation induced the overexpression of GPR40, GPR120, and several inflammatory cytokines, with correlations between ileal concentrations of tumor necrosis factor (TNF)-a and GPR expression levels; however, inflammation did not induce the expression of proglucagon, a precursor of GLP-2 in CD patients.	25447053
Inflammatory abnormality of the eye	Altered Intercellular Communication	Panuveitis was the most common type of ocular inflammation (28 eyes), independent of HIV status.	25447116
Inflammatory abnormality of the eye	Altered Intercellular Communication	Syphilis is an uncommon cause of ocular inflammation in both HIV-negative and HIV-positive patients.	25447116
Inflammation, Fibrosis Assessment, Injury of kidney	Altered Intercellular Communication	Effects of left ventricular assist device support on biomarkers of cardiovascular stress, fibrosis, fluid homeostasis, inflammation, and renal injury.	25447345
Inflammation, Fibrosis Assessment, Myocardial, Injury of kidney	Altered Intercellular Communication	Changes in markers of myocardial stress, fibrosis, inflammation, fluid homeostasis, and renal injury in this setting are unknown.	25447345
Inflammation, Dental Pulp Necrosis	Altered Intercellular Communication	In many cases, the crack extended to the pulp, leading to reactions with intensities ranging from acute inflammation to total pulpal necrosis.	25447500
Inflammation, Coronary Artery Vasospasm, Atherosclerosis	Altered Intercellular Communication	Differences and interactions between risk factors for coronary spasm and atherosclerosis--smoking, aging, inflammation, and blood pressure.	25447646
Inflammation, Injury of kidney	Altered Intercellular Communication	Label-free quantitative proteomics by nanoLC-MS/MS was applied to urine of severe AP patients and found that severe AP is accompanied with kidney injury and inflammation.	25447703
TAO brand of troleandomycin, Uveitis	Altered Intercellular Communication	Extraocular muscle inflammation in TAO improved with treatment.	25448468
Alzheimers Disease", Data types - Address, physiopathological	Altered Intercellular Communication	Since glutamate neurotransmission is disrupted in Alzheimer's disease (AD), NPR levels measured from plasma represent a potential biomarker for synaptic dysfunction associated with AD.	25449907
Hyperglycemia, Inflammation, Obesity	Altered Intercellular Communication	Further research is needed to harness this novel and beneficial property of E4orf1 to improve hyperglycemia despite chronic inflammation that is commonly present in aging and obesity.	25450249
Inflammation, Cystic Fibrosis	Altered Intercellular Communication	It is known that patients with cystic fibrosis have a chronic inflammation status and that b pancreatic cells are very sensitive to oxidative stress.	25450813
Degenerative polyarthritis, Inflammation, Weight decreased	Altered Intercellular Communication	To describe associations between total and regional body fat mass loss and reduction of systemic levels of inflammation (C-reactive protein (CRP) and interleukin-6 (IL-6)) in obese, older adults with osteoarthritis (OA), undergoing intentional weight loss.	25450847
Abdominal Fat, Inflammation	Altered Intercellular Communication	Loss of abdominal fat volume was also associated with reduced inflammation, independent of total body fat mass; although models containing measures of total adiposity yielded the best fit.	25450847
Inflammation, Mycoses, Lobomycosis	Altered Intercellular Communication	Jorge Lobo's disease is a rare mycosis characterized by chronic inflammation, which causes skin lesions in the absence of visceral dissemination.	25450888
Inflammation, Impaired cognition, millicurie	Altered Intercellular Communication	CHF5074 (CSP-1103) has been shown to improve cognition and reduce brain inflammation in patients with mild cognitive impairment (MCI).	25450955
Inflammation, Haemoconcentration	Altered Intercellular Communication	More volume was administered in younger patients and in patients with evidence of hemoconcentration and inflammation.	25451185
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Association between metabolically unhealthy overweight/obesity and chronic kidney disease: the role of inflammation.	25451190
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation might mediate at least part of the association between metabolic changes and CKD prevalence.	25451190
Inflammation, sleep loss	Altered Intercellular Communication	Sleep loss activates cellular inflammation and signal transducer and activator of transcription (STAT) family proteins in humans.	25451613
Inflammation, Cardiovascular Diseases, Dyssomnias, Diabetes Mellitus, Malignant Neoplasms, Arthritis	Altered Intercellular Communication	Sleep disturbance and short sleep duration are associated with inflammation and related disorders including cardiovascular disease, arthritis, diabetes mellitus, and certain cancers.	25451613
Inflammation, Inflammatory disorder, Malignant Neoplasms	Altered Intercellular Communication	Treatments that target short sleep duration have the potential to constrain inflammation and reduce the risk for inflammatory disorders and some cancers in humans.	25451613
Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation-induced atrial fibrillation: pathophysiological perspectives and clinical implications.	25453387
Inflammation	Altered Intercellular Communication	Growing evidence suggests that inflammation plays a significant role in the onset and recurrence of AF.	25453387
Inflammation	Altered Intercellular Communication	The role of inflammation in the pathogenesis of AF has important clinical implications of which many practitioners are unfamiliar.	25453387
Appendicitis, CTCAE	Altered Intercellular Communication	In this article, we describe a case of a 29-year-old male, who presents the emergency department with inflammation-induced AF, secondary to acute appendicitis.	25453387
Inflammation, High Sensitivity C-Reactive Protein Measurement	Altered Intercellular Communication	Subgroup analysis showed 40 participants without signs of low-grade inflammation (hsCRP<3 mg/l, subgroup 1) and 21 participants with low-grade inflammation at baseline (hsCRP>=3 mg/l, subgroup 2).	25453395
Inflammation, Multiple Sclerosis, Liver Dysfunction	Altered Intercellular Communication	It is unknown whether diets with a high dietary total antioxidant capacity (TAC) can modify oxidative stress, low-grade inflammation, or liver dysfunction, all of which are risk factors for multiple sclerosis disease.	25453518
Pancreatitis, Infectious colitis	Altered Intercellular Communication	Computed tomography scan of her abdomen was performed and revealed findings consistent with infectious colitis, without signs of pancreatic inflammation or other findings associated with pancreatitis.	25453861
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Morphological studies included analysis of growth pattern, cell proliferation (Ki-67/MIB1 expression) and parameters of intra- and peri-tumoral remodelling (inflammation, fibrosis and necrosis).	25454198
Granuloma, Pneumonia, Interstitial	Altered Intercellular Communication	Based on our findings in this series and the most recent publications of the subject, we propose the following set of diagnostic criteria for PPFE: multilobar subpleural and/or centrilobular fibrous interstitial pneumonia characterized by an extensive (>80%) proliferation of elastic fibers in nonatelectatic lung, along with absent to mild chronic inflammation, and absent to rare granulomas.	25454481
Inflammation	Altered Intercellular Communication	However, severity of inflammation appears to be a critical factor in disease pathogenesis.	25454482
Inflammation, Ischemic	Altered Intercellular Communication	Carotid inflammation on 18F-fluorodeoxyglucose positron emission tomography associates with recurrent ischemic lesions.	25454641
Inflammation, Ischemic stroke	Altered Intercellular Communication	Inflammation plays an important role in the development of ischemic stroke.	25454641
Inflammation, Ischemic, Carotid Atherosclerosis	Altered Intercellular Communication	We hypothesized that inflammation of carotid atherosclerosis, as measured by (18)F-fluorodeoxyglucose (FDG) uptake on positron emission tomography (PET), associates with the early recurrent ischemic lesions (ERILs).	25454641
Carotid Atherosclerosis	Altered Intercellular Communication	Increased carotid plaque inflammation, as measured by FDG uptake on PET, may be a useful marker for identifying patients with symptomatic carotid atherosclerosis who are at risk of recurrence.	25454641
Inflammation, cervical cancer	Altered Intercellular Communication	Elevated TLR9 levels without HPV clearance in persistently infected women could drive inflammation thereby contributing to cervical cancer risk.	25454809
Inflammation, Asthma	Altered Intercellular Communication	The lack of predictive value of any pathologic measure in infancy, reported here for the first time to our knowledge, demonstrates that pathologic processes determining the inception of asthma, which are as yet undescribed, are different from the eosinophilic inflammation associated with ongoing disease.	25455519
Airway structure	Altered Intercellular Communication	This study suggests that FENO values higher than 27ppb are likely to be abnormal and would reflect airway inflammation in children as those in the present study.	25456527
Cardiovascular morbidity, Inflammation	Altered Intercellular Communication	In addition, we examined the impact of physical activity changes over time on 2 known mediators of cardiovascular morbidity: parasympathetic tone and inflammation.	25456561
Inflammation, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	In this cohort of patients with severe asthma, the majority displayed indices of persistent airflow limitation and eosinophilic inflammation despite high-dose corticosteroids, suggesting potential for eosinophil-targeted biotherapies.	25456708
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation is a key factor in the onset and progression of Alzheimer's disease (AD).	25456845
Inflammation, Hypertension, CTCAE, Liver Cirrhosis	Altered Intercellular Communication	Inflammation, collagen deposition and tissue remodelling are involved in the pathogenesis and complications of cirrhosis with portal hypertension.	25457205
vascular inflammations	Altered Intercellular Communication	Galectin-3, a member of galectines, a family of b-galactoside-specific lectins, has been reported to propagate vascular inflammation.	25457298
Neurogenic Inflammation, Myalgia, CTCAE 5	Altered Intercellular Communication	It is also known as centrally mediated myalgia associated with neurogenic inflammation.	25457825
Inflammation, Endothelial dysfunction, Kidney Diseases	Altered Intercellular Communication	Incipient nephropathy was associated with more pronounced alterations in vitamin B6 metabolism and stronger indications of endothelial dysfunction and inflammation.	25458341
Inflammation, Primary malignant neoplasm, Ulceration, CTCAE, Traumatic injury	Altered Intercellular Communication	This hierarchical model of stem cell genesis leads to a very low prevalence of cancer, unless the orderly progression of the hierarchy is disturbed by inflammation, ulceration or trauma.	25459141
Inflammation, neuroborreliosis, Polyneuritis	Altered Intercellular Communication	A unique case of adolescent neuroborreliosis presenting with multiple cranial neuritis and cochlear inflammation on magnetic resonance imaging.	25459362
Inflammation, Polyneuritis	Altered Intercellular Communication	Neuroimaging demonstrated cranial polyneuritis and right-sided cochlear inflammation.	25459362
hearing impairment, Inflammation, neuroborreliosis	Altered Intercellular Communication	Additionally, cochlear inflammation along with cranial nerve VIII inflammation may contribute to hearing loss in patients with neuroborreliosis.	25459362
Inflammation, Failure (biologic function)	Altered Intercellular Communication	Other major reasons for failure were inappropriate length of tube insertion in the primary group and inflammation in the revision group.	25459376
Inflammation, Failure (biologic function)	Altered Intercellular Communication	The most common cause of failure was medial migration of the Jones tube; however, inappropriate tube insertion in primary surgery and severe inflammation in revision may also be concerns.	25459376
Airway structure, ARCN1 gene	Altered Intercellular Communication	Clinical characteristics and airway inflammation profile of COPD persistent sputum producers.	25459449
ARCN1 gene, Airway structure	Altered Intercellular Communication	We hypothesized that COPD patients with persistent sputum production have a different profile of airway inflammation, and more severe clinical characteristics.	25459449
Airway structure, ARCN1 gene	Altered Intercellular Communication	To compare the airway inflammation profile and clinical characteristics of COPD persistent and non-persistent sputum producers.	25459449
Diastolic dysfunction, Inflammation, Heart failure, Monocytosis	Altered Intercellular Communication	Exaggerated inflammation and monocytosis associate with diastolic dysfunction in heart failure with preserved ejection fraction: evidence of M2 macrophage activation in disease pathogenesis.	25459685
Inflammation, Fibrosis Assessment, Heart failure, Myocardial lymphocytic infiltration	Altered Intercellular Communication	Heart failure with preserved ejection fraction (HFPEF) is a major health problem associated with myocardial leukocyte infiltration, inflammation, and fibrosis.	25459685
Inflammation, Monocytosis	Altered Intercellular Communication	Increased peripheral inflammation, monocytosis, and monocyte differentiation to anti-inflammatory/profibrotic M2 macrophages likely associate with HFPEF and its precedent asymptomatic LVDD phase.	25459685
Inflammation, Hypertension, CTCAE, Metabolic Syndrome X	Altered Intercellular Communication	No relationship of anti-ox LDL level with cognition, hypertension, metabolic syndrome, inflammation indicators and serum lipid levels was observed.	25459919
Inflammation, Pain Distress Question, Psychiatric, Disability, Liver Cirrhosis	Altered Intercellular Communication	Inflammation, psychiatric symptoms, and opioid use are associated with pain and disability in patients with cirrhosis.	25460019
Pain Distress Question, Inflammation, Psychiatric, Disability, Liver Cirrhosis	Altered Intercellular Communication	We investigated whether the pain and disability in patients with cirrhosis are associated with systemic inflammation and psychiatric symptoms.	25460019
Pain Distress Question, Inflammation, Psychiatric, Disability, Liver Cirrhosis	Altered Intercellular Communication	Pain and disability are common among patients with cirrhosis, and are associated with inflammation, psychiatric symptoms, and opioid use, which potentially are modifiable.	25460019
Pain Distress Question, Inflammation, Psychiatric	Altered Intercellular Communication	Although opioids are used commonly to treat pain, psychiatric symptoms and inflammation also might be treatment targets in this population.	25460019
Inflammation, Obesity, Abdominal, metabolic disturbance, Bipolar Disorder	Altered Intercellular Communication	The longitudinal association between inflammation and incident depressive symptoms in men: the effects of hs-CRP are independent of abdominal obesity and metabolic disturbances.	25460540
Inflammation, Obesity, Abdominal, metabolic disturbance, Bipolar Disorder	Altered Intercellular Communication	This cohort study evaluates whether the association between low-grade inflammation and incident depressive symptoms is independent of abdominal obesity and metabolic disturbances.	25460540
Obesity, Abdominal, metabolic disturbance	Altered Intercellular Communication	Further investigation into the role of abdominal obesity and metabolic disturbances in the inflammation-depression hypothesis is warranted.	25460540
Inflammation, Fracture	Altered Intercellular Communication	Low-grade inflammation is associated with fractures, while the relationship between inflammation and bone mineral density (BMD) is less clear.	25460573
Inflammation, Fracture	Altered Intercellular Communication	We infer that inflammation influence fracture risk in both women and men, although the biological mechanisms may differ between the genders.	25460573
Hepatitis C, Chronic, Hepatitis	Altered Intercellular Communication	Absolute quantification of serum microRNA-122 and its correlation with liver inflammation grade and serum alanine aminotransferase in chronic hepatitis C patients.	25461662
Hepatitis	Altered Intercellular Communication	However, there was no significant association between microRNA-122 and ALT serum levels or liver inflammation grades.	25461662
Carcinogenic Chlorinated Hydrocarbon, Injury of liver, Hepatitis	Altered Intercellular Communication	However, this biomarker for acute liver injury did not reflect the liver inflammation activity in CHC patients.	25461662
Inflammation	Altered Intercellular Communication	Prevention of ERM formation by aggressive control of inflammation is important.	25462433
Aneurysm, Inflammation, Iliac Aneurysm	Altered Intercellular Communication	Progression of perianeurysmal inflammation after endovascular aneurysm repair for inflammatory abdominal aortic and bilateral common iliac artery aneurysms.	25462547
Aneurysm, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	The use of endovascular aneurysm repair (EVAR) to treat inflammatory abdominal aortic aneurysms (IAAAs) has been reported, and this procedure appears to be preferable to open surgical repair because of intraoperative difficulties related to inflammation.	25462547
Inflammation	Altered Intercellular Communication	The perianeurysmal inflammation worsened postoperatively, requiring the placement of a ureteric stent.	25462547
Inflammation	Altered Intercellular Communication	The only risk factor for IAA was the intraoperative grade of inflammation (P=0.028).	25462984
Inflammation	Altered Intercellular Communication	ASA score (odds ratio: 1.992, P=0.032) and the intraoperative grade of inflammation (odds ratio: 1.573, P=0.006) remained significant in the multivariate analysis for SSI.	25462984
vascular inflammations	Altered Intercellular Communication	Positive correlation between malondialdehyde-modified low-density lipoprotein cholesterol and vascular inflammation evaluated by 18F-FDG PET/CT.	25463065
vascular inflammations	Altered Intercellular Communication	Vascular inflammation, was measured as blood-normalized standardized (18)F-FDG uptake value, known as the target-to-background ratio (TBR) of carotid arteries.	25463065
vascular inflammations, atherosclerotic	Altered Intercellular Communication	Circulating MDA-LDL may be a more useful clinical biomarker for vascular inflammation within the atherosclerotic plaques than hsCRP or ADMA.	25463065
Inflammation, Endothelial dysfunction, Injury of kidney	Altered Intercellular Communication	Low density lipoprotein cholesterol (LDL-C) is associated with endothelial dysfunction, inflammation and increased vasoconstriction, which are involved in the development of contrast-induced acute kidney injury (CI-AKI).	25463073
Inflammation, Blood Clot	Altered Intercellular Communication	Coronary thrombus composition: links with inflammation, platelet and endothelial markers.	25463088
Vascular Diseases, Congenital Abnormality	Altered Intercellular Communication	Preliminary evidence suggests that intact parathyroid hormone (iPTH) and bone mineral abnormalities may contribute to the development of vascular disease and are associated with reduced survival in the general population.	25463096
Inflammation, Atherosclerosis	Altered Intercellular Communication	inflammation (CXCR4, CXCL2, PTGS2), immune imbalance (IL-8, IL-Iss, CCL3), and active atherosclerosis (DUSP-1, OSM, ATF3).	25463097
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Altered lipidome and antioxidative activity of small, dense HDL in normolipidemic rheumatoid arthritis: relevance of inflammation.	25463101
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Such activities are enriched in small, dense HDL and can be compromised under conditions of chronic inflammation like rheumatoid arthritis (RA).	25463101
Refractory anemias, Inflammation, Hemophilia A	Altered Intercellular Communication	These data revealed that (i) despite normolipidemic state, the lipidome of small, dense HDL was altered in RA and (ii) high levels of inflammation can be responsible for the functional deficiency of small, dense HDL in RA.	25463101
Inflammation, Thrombosis	Altered Intercellular Communication	At the light of a literature review, we discussed our surgical strategy and the inflammation of the aortic wall as local factor of thrombosis that has never been previously described.	25463334
Inflammation	Altered Intercellular Communication	Since inflammation is very limited in these wounds reduced numbers or even absence of immune cells might be responsible for scarless foetal wound healing.	25463905
Inflammation	Altered Intercellular Communication	Systemic oxidative stress and inflammation levels were also increased in both patient groups compared to controls (p<0.005, both).	25464271
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Major adverse cardiovascular events (MACEs) in patients with or without cardiovascular disease (CVD) are greatly affected by various factors associated with metabolism and inflammation.	25464435
Respiratory Syncytial Virus Infections, Pneumonitis	Altered Intercellular Communication	Importantly, the interaction of PD-1 with its ligand PD-L1 is vital to restrict the pro-inflammatory activities of lung effector T cells in situ, thereby inhibiting the development of excessive pulmonary inflammation and injury during RSV infection.	25465101
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Inflammation may reduce hippocampal volume by blocking neurogenesis and promoting neurodegeneration.	25465168
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	Posttraumatic stress disorder (PTSD) has been linked with both elevated inflammation and reduced hippocampal volume.	25465168
Inflammation, hepcidin, Anemia	Altered Intercellular Communication	Hepatic hepcidin-25 production is stimulated by systemic inflammation, and it interferes with the body's utilization of iron, leading to anemia.	25465232
Fibrosis Assessment, Thyroiditis, Haiti	Altered Intercellular Communication	IgG4-related HT is a new subtype characterized by thyroid inflammation rich in IgG4-positive plasma cells and marked fibrosis.	25465611
Inflammation, Triple-Negative Breast Cancer Finding, Neoplasms	Altered Intercellular Communication	Gene expression of cancer-adjacent tissues shows that triple-negative (Claudin-low or basal-like) tumors exhibit increased expression of genes involved in inflammation and immune response.	25465802
Chemoradiotherapy, Inflammation, Non-Small Cell Lung Carcinoma, Esophagitis	Altered Intercellular Communication	We sought to investigate whether three serum miRNAs related to immunity or inflammation were associated with esophagitis induced by chemoradiation therapy (CRT) for non-small cell lung cancer (NSCLC).	25466375
Pharyngitis, Abdominal Pain	Altered Intercellular Communication	The dominant symptoms at the department were abdominal pain and throat inflammation.	25466421
Inflammation, Acute Disease	Altered Intercellular Communication	An acute disease is regularly associated with inflammation, decreased food intake, and low physical activity; the consequence is loss of muscle mass.	25466662
Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding, Obesity	Altered Intercellular Communication	Also, given the strong relationship between atrial fibrillation (AF), obesity and inflammation, the purpose of this study was to investigate the association of non-valvular AF with epicardial and periatrial fat.	25466809
Inflammation, Corneal Opacity	Altered Intercellular Communication	Examination of the left eye revealed multiple corneal opacities, deep stromal neovascularization and anterior chamber inflammation.	25467290
Arthritis, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Even SLE patients without clinical signs of joint inflammation demonstrated US abnormalities.	25467390
Kidney Failure, Chronic, Renal function, Albuminuria	Altered Intercellular Communication	Inflammation-related microvasculr disease, albuminuria, and rapid deterioration of renal function can accelerate the development of end-stage renal disease (ESRD).	25468738
Kidney Failure, Chronic, Inflammation, Fracture, Disease	Altered Intercellular Communication	The role of hip fracture (HFr), a disorder that involves inflammation, in the development of ESRD has not been fully investigated.	25468738
Kidney Failure, Chronic, Inflammation, Microvascular Angina, Chronic disease	Altered Intercellular Communication	This study is the first to report that HFr, in combination with underlying osteoporosis-related chronic illness, microvascular disease and chronic inflammation, is associated with an increased risk of ESRD, particularly among relatively younger people.	25468738
Inflammation, Anastomotic Leak, Abdominal Abscess	Altered Intercellular Communication	Amplification of inflammation and angiogenesis might be one of the mechanisms responsible for the higher recurrence rate observed in patients with anastomotic leakage or intra-abdominal abscess.	25468742
Inflammation, Abscess of lacrimal gland, Dacryoadenitis	Altered Intercellular Communication	Dacryoadenitis, a condition defined as inflammation of the lacrimal gland, has many etiologies; rarely is it associated with a lacrimal gland abscess.	25469005
Tuberculosis, Leishmaniasis, Granulomatous inflammation, Aspergillosis, Acute suppurative inflammation	Altered Intercellular Communication	In this study, there were 13 cases of tuberculosis, 25 cases of granulomatous inflammation, 10 cases of acute suppurative inflammation, and one case each of leishmaniasis, aspergillosis and extramedullary hematopoiesis.	25469450
Inflammation, Obesity, Abdominal, Impaired cognition	Altered Intercellular Communication	Abdominal obesity contributes to neurocognitive impairment in HIV-infected patients with increased inflammation and immune activation.	25469522
Inflammation, Obesity, Abdominal	Altered Intercellular Communication	Abdominal obesity, inflammation, and central nervous system immune activation are potential therapeutic targets for NCI in HIV-positive patients.	25469522
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	Although chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by Th2 inflammation, the mechanism underlying the onset and amplification of this inflammation has not been fully elucidated.	25469646
Inflammation, Myeloid	Altered Intercellular Communication	Myeloid DCs thus may indirectly contribute to the inflammation observed in CRSwNP.	25469646
Inflammation	Altered Intercellular Communication	These results support growing evidence showing that inflammation is associated with cancer-related symptoms, and they suggest that racial/ethnic factors contribute to this association.	25469832
Refractory anemias, Inflammation	Altered Intercellular Communication	Systemic inflammation is proposed to play a fundamental role in the altered lipid metabolism associated with RA; however, the underlying mechanisms are unknown.	25470338
Inflammation, Malaria, Tuberculosis	Altered Intercellular Communication	Based on demonstrated roles in up-regulating innate immunity, decreasing inflammation, and reducing the severity of disease in illnesses such as tuberculosis and influenza, we hypothesized that poor vitamin D status would be associated with severe malaria.	25470777
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	As many mesothelial cells are simultaneously exposed to asbestos fibers and to asbestos-induced inflammation, it may be possible that more than one cell undergoes malignant transformation during the process that gives rise to MM, and result in a polyclonal malignancy.	25471750
Inflammation	Altered Intercellular Communication	Inflammation could be an underlying confounding factor explaining the increased mortality in these patients.	25472577
MCC protocol, Inflammation	Altered Intercellular Communication	Evidence is emerging that inflammation and immune response play a role in the pathogenesis of CCM.	25472749
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Chronic inflammation is a key feature of colorectal cancer (CRC), meaning that inflammatory biomarkers may be useful for its diagnosis.	25472811
vascular inflammations, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	ACE inhibitors potently reduce vascular inflammation, results of an open proof-of-concept study in the abdominal aortic aneurysm.	25474105
APP gene, vascular inflammations	Altered Intercellular Communication	ACE inhibition quenches multiple aspects of vascular inflammation in AAA.	25474105
Inflammation, Asthma, Wheezing	Altered Intercellular Communication	To assess whether exhaled biomarkers, expression of inflammation genes, and early lung function measurements can improve a reliable asthma prediction in preschool wheezing children.	25474185
Inflammation, Asthma	Altered Intercellular Communication	Adding information on exhaled VOCs and possibly expression of inflammation genes to the API significantly improves an accurate asthma diagnosis in preschool children.	25474185
Inflammation, Atherosclerosis, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	A considerable amount of evidence indicates that inflammation is responsible for the development of atherosclerosis in patients with ACS.	25474223
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	These findings demonstrate for the first time that sAxl does have a role in ACS, presumably connected to the inflammation.	25474223
Airway structure, ARCN1 gene	Altered Intercellular Communication	Supplementing defect in club cell secretory protein attenuates airway inflammation in COPD.	25474370
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Citrullination of proteins is well described in rheumatoid arthritis (RA), and hypercitrullination of proteins may be related to inflammation in general.	25475141
Inflammation, CRNKL1 wt Allele, Liver Cirrhosis	Altered Intercellular Communication	Whereas expression of iron-regulatory genes was markedly down-regulated, genes related to endoplasmic reticulum stress, apoptosis, and inflammation were up-regulated in ACLF patients, compared to patients with cirrhosis.	25475192
Inflammation, Squamous cell carcinoma, SERPINB3 wt Allele	Altered Intercellular Communication	An inflammation, which is innate in the carcinogenesis of oral squamous cell carcinoma (OSCC), frequently complicates the image analysis because of the limitations of (18)F-FDG and maximum standardized uptake values (SUV(max)).	25476535
Inflammation, Neoplasms	Altered Intercellular Communication	The whole tumor dissected from surgery was measured and sectioned for pathologic analysis of tumor inflammation grade and Ki-67 labeling index.	25476535
Inflammation, Inflammatory Myofibroblastic Tumor, Neoplasms	Altered Intercellular Communication	The SUV(max )ratio of (18)F-FDG to (18)F-FAMT was higher in inflammatory tumors (P < 0.05) whereas the corresponding value in tumors with a low inflammation grade was kept low.	25476535
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Patients were classified based on final histopathological findings into the groups: no appendiceal inflammation, non-perforated appendicitis and perforated appendicitis.	25476715
Inflammation, Appendicitis, CTCAE, Appendicitis Perforated, CTCAE	Altered Intercellular Communication	Of 493 analysed patients, 125 (25%) had no appendiceal inflammation, 312 (64%) had non-perforated appendicitis and 56 (11%) had perforated appendicitis.	25476715
Inflammation, Hyperbilirubinemia, Appendicitis, CTCAE	Altered Intercellular Communication	Hyperbilirubinaemia is present in acute appendicitis but has a low diagnostic accuracy in discriminating between any appendicitis versus no appendiceal inflammation and perforated versus non-perforated appendicitis and is, therefore, of limited value in clinical routine.	25476715
Inflammation, Dental caries	Altered Intercellular Communication	Cytokines are associated with levels of inflammation and are involved in caries, pulpal, and periapical tissue destruction.	25476976
Inflammation, Obesity	Altered Intercellular Communication	Human adenovirus type 36 (Ad36) as an obesity agent induces adiposity by increasing glucose uptake and promoting chronic inflammation in fat tissues; in contrast, exercise reduces total body fat and inflammation.	25479564
Inflammation, Weight decreased	Altered Intercellular Communication	Similarly, Ad36-infected mice were resistant to weight loss and exhibited chronic inflammation of their adipose tissues despite frequent exercise.	25479564
ARCN1 gene, Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Participants were divided into 5 groups: 1) no COPD, no CHD; 2) COPD without inflammation, no CHD; 3) COPD with inflammation, no CHD; 4) CHD only, and 5) CHD + COPD.	25480156
ARCN1 gene, Inflammation	Altered Intercellular Communication	A novel "inflammatory" COPD designation included those with COPD and clinical evidence of inflammation (i.e., CRP >=95.24 nmol/L).	25480156
ARCN1 gene, Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	For total mortality, the risk was significant for the four groups: the non-inflammatory COPD group; the COPD with inflammation group, the CHD group, and the COPD + CHD group.	25480156
ARCN1 gene, Inflammation, GDC Comorbidity Terminology, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Moreover, given that COPD results from inflammation, the systemic inflammation associated with COPD may have worsened comorbid conditions and may have lead to the increased total mortality found in the COPD with inflammation and COPD + CHD groups which requires further investigation.	25480156
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	The complex pathogenesis of Alzheimer's disease (AD) involves multiple contributing factors, including amyloid b (Ab) peptide accumulation, inflammation and oxidative stress.	25481013
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	[Expression of cadherin-11 in rheumatoid arthritis synovium and its correlation with inflammation].	25481189
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To explore the pattern of cadherin-11 expression and its relationship with synovial inflammation in rheumatoid arthritis (RA), and study the regulatory effects of cytokines on cadherin-11 expression on RA fibroblast-like synoviocytes (RAFLS).	25481189
Synovitis	Altered Intercellular Communication	After HE staining, synovitis score was determined according to Rooney's inflammation score system.	25481189
Refractory anemias	Altered Intercellular Communication	The expression of cadherin-11 in RA synovium was semi-quantified by immunohistochemical staining, and its correlations with Rooney's inflammation score and systematic inflammatory markers were analyzed statistically.	25481189
Pain Distress Question, Inflammation	Altered Intercellular Communication	No pain or any other signs of inflammation were observed.	25481274
Inflammation	Altered Intercellular Communication	We also showed that behavioural factors contributed the most to SES differences in inflammation.	25482420
Inflammation, GDC Disease Response Terminology	Altered Intercellular Communication	Inflammation plays a considerable role in the pathogenesis of T2DM and DR.	25483847
Inflammation	Altered Intercellular Communication	There is a question of closing tissue defects after the elimination period of acute inflammation.	25484157
Inflammation, Blood Vessel, Hypoxemia, Pre-Eclampsia	Altered Intercellular Communication	Faulty placentation manifests in the mother as preeclampsia with vascular damage, enhanced systemic inflammation, and insulin resistance; in the placenta as oxygen and nutrient transfer restriction and oxidative stress; and in the fetus as growth restriction and progressive hypoxemia.	25485869
Inflammation, Gallbladder	Altered Intercellular Communication	Percutaneous cholecystostomy (PC) is a safe treatment for acute inflammation of the gall bladder.	25487543
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	It is unknown whether joint inflammation precedes other articular tissue damage in osteoarthritis.	25488799
Communicable Diseases, Inflammation, Infection	Altered Intercellular Communication	Finely tuned to respond quickly to infections, neutrophils have amazing abilities to migrate fast and efficiently towards sites of infection and inflammation.	25489947
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	The risk of incident type 2 diabetes in a Korean metabolically healthy obese population: the role of systemic inflammation.	25490279
Inflammation, Units Of Measure - Siemens, Diabetes Mellitus	Altered Intercellular Communication	This study sought to investigate whether the metabolically healthy obese (MHO) phenotype is associated with an increased risk of incident type 2 diabetes in a Korean population and, if so, whether systemic inflammation affects this risk in MHO individuals.	25490279
Inflammation, Units Of Measure - Siemens	Altered Intercellular Communication	However, the risk of the MHO group varied according to the degree of systemic inflammation.	25490279
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Compared with the MHNO/low systemic inflammation group, the risk of type 2 diabetes in the MHO/low systemic inflammation group was not significantly elevated (multivariate-adjusted HR, 1.61; 95% CI, 0.77-3.34).	25490279
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	However, the MHO/high systemic inflammation group had an elevated risk of incident type 2 diabetes (multivariate-adjusted HR, 3.73; 95% CI 2.36-5.88).	25490279
Autoimmune Diseases, Idiopathic Inflammatory Myopathies, Myositis	Altered Intercellular Communication	Idiopathic inflammatory myopathies (IIM) are a rare group of autoimmune diseases characterized by muscle inflammation.	25490616
Inflammation, Primary malignant neoplasm, Neoplasm Metastasis, Laryngeal Squamous Cell Carcinoma	Altered Intercellular Communication	Inflammation and cancer: role of annexin A1 and FPR2/ALX in proliferation and metastasis in human laryngeal squamous cell carcinoma.	25490767
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	After surgery, fibrosis, steatosis, lobular inflammation, portal inflammation, and ballooning in the background liver were assessed.	25490872
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a common health problem and it is associated with oxidant/antioxidant imbalance and systemic inflammation.	25491624
Communicable Diseases, Inflammation	Altered Intercellular Communication	HP+ GC appeared to show a higher proliferative capacity, more extensive spread, and more rapid progression, and inflammation associated with HP infection was suggested to be involved in the proliferation of this type of GC.	25491775
Communicable Diseases, Helicobacter pylori, Inflammation, Malignant neoplasm of stomach	Altered Intercellular Communication	Stomach cancer can occur during chronic inflammation from Helicobacter pylori (HP) infection, and its occurrence can be suppressed by eradication of HP.	25491907
Inflammation, MS gene	Altered Intercellular Communication	Astroglial PGC-1alpha increases mitochondrial antioxidant capacity and suppresses inflammation: implications for multiple sclerosis.	25492529
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Our findings suggest that increased astrocytic PGC-1a in active MS lesions might initially function as an endogenous protective mechanism to dampen oxidative damage and inflammation thereby reducing neurodegeneration.	25492529
Prostate carcinoma, Structure of posterior cerebral artery	Altered Intercellular Communication	Long-term exposure to persistent pollutants with hormonal properties (endocrine-disrupting chemicals; EDCs) may contribute to the risk of prostate cancer (PCa).	25493337
Inflammation	Altered Intercellular Communication	Pulmonary function, physical fitness (6MWD) and asthmatic inflammation (FENO) were measured at T0 and T1.	25494552
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Association of altered hemorheology with oxidative stress and inflammation in metabolic syndrome.	25494675
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	The objective of the study was to find out if the altered hemorheology shown in MetS in our previous study is associated with chronic inflammation and oxidative stress in the same subjects.	25494675
Inflammation	Altered Intercellular Communication	We found a significant association of altered hemorheology with chronic inflammation and oxidative stress in MetS.	25494675
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Alterations of hemorheology in MetS are probably due to the effect of chronic inflammation and oxidative stress.	25494675
Inflammation	Altered Intercellular Communication	The negative effects of chronic inflammation and oxidative stress on the cardiovascular system could be due to the resulting altered hemorheology.	25494675
Thrombosis, Postthrombotic Syndrome	Altered Intercellular Communication	Inflammation markers and their trajectories after deep vein thrombosis in relation to risk of post-thrombotic syndrome.	25495610
Metabolic Syndrome X	Altered Intercellular Communication	These results provide new evidence that the relatively rarely-studied active hormonal form of vitamin D, 1,25(OH)2D, is associated with metabolic syndrome and its components, and confirm prior findings for 25(OH)D. The finding that 1,25(OH)2D is related to high-density lipoprotein, while 25(OH)D is not, suggests that there may be an independent mechanism of action for 1,25(OH)2D in relation to metabolic dysregulation.	25496802
Inflammation, Papillon-Lefevre Disease	Altered Intercellular Communication	Results showed that periodontal inflammation of PLS peaked at teenage years, but declined with time.	25497043
Inflammation, Traumatic injury, Multiple Trauma	Altered Intercellular Communication	During sterile inflammation, polytrauma and burn trauma patients initially present with high serum concentrations of myeloid-related proteins (MRPs).	25497086
Inflammation, Infection	Altered Intercellular Communication	Our data therefore indicate that alarmin-triggered phagocyte tolerance represents a regulatory mechanism for the susceptibility of neonates during systemic infections and sterile inflammation.	25497086
Inflammation	Altered Intercellular Communication	Moreover, cardiac inflammation did not influence Nampt expression, and Nampt concentrations did not modulate cardiac inflammation in DCMi.	25498756
THANATOPHORIC DYSPLASIA, TYPE I (disorder), Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	Altered Intercellular Communication	This report confirms and expands the spectrum of inflammatory demyelinating conditions associated with IVF and suggests possible hormonal influence in the development of TD.	25499758
Multiple Organ Failure, Pancreatitis	Altered Intercellular Communication	Cytokine coadministration resulted in higher pancreatic and lung inflammation than caerulein alone, but only triolein coadministration caused peripancreatic fat stranding, higher cytokines, UFAs, multisystem organ failure (MSOF) and mortality in 97% animals, which were prevented by orlistat.	25500204
Inflammation, Lipolysis	Altered Intercellular Communication	However, UFAs generated via peripancreatic fat lipolysis causes worse inflammation and MSOF, converting mild AP to SAP.	25500204
Central Nervous System	Altered Intercellular Communication	Inflammation-induced alterations in central nervous system (CNS) metabolism have focused on glutamate.	25500218
Inflammation, Depression, CTCAE, Disease	Altered Intercellular Communication	Increased glutamate has also been found in depression, a disorder associated with increased inflammation.	25500218
Autoimmune Diseases, Tumor necrosis, Inflammation	Altered Intercellular Communication	The tumor necrosis factor receptor-associated factor 1/complement C5 (TRAF1/C5) genes have been suggested as two candidate genes for conferring susceptibility to autoimmunity and inflammation.	25500258
Inflammation, Swelling, Obstruction	Altered Intercellular Communication	chronic swelling or obstruction and inflammation of the salivary duct.	25500629
Inflammation, Necrosis	Altered Intercellular Communication	Nongranulomatous inflammation with fibrinoid necrosis of medium-sized vessels occurred equally in both groups (>90%).	25500710
Myositis	Altered Intercellular Communication	Visual grading of the bone scans had a sensitivity and specificity of 74 and 90.9 %, respectively, for the assessment of muscle inflammation.	25501462
Parkinson Disease, Inflammation, Parkinsonian Disorders	Altered Intercellular Communication	Parkinson's disease and atypical forms of parkinsonism occur mainly in the elderly, with oxidative stress and inflammation in afflicted cells.	25501556
Inflammation	Altered Intercellular Communication	If the patient has undergone previous intra-abdominal operations or chronic inflammation of the pancreas is found, special care of the spleen during the operation is necessary.	25501876
Inflammation	Altered Intercellular Communication	CCL18 is a chemokine that is primarily expressed in monocytes, macrophages and immature dendritic cells and plays a crucial role in immune and inflammation responses.	25502147
Inflammation	Altered Intercellular Communication	These results suggest that the effect of losartan on insulin resistance is associated with the reduction of oxidative stress and inflammation in patients with type 2 DKD as well as the activation of insulin signal pathway in insulin-resistance 3T3-L1 adipocytes through modulation of PI3K pathway.	25502581
palladium	Altered Intercellular Communication	The lack of modulations of bilateral arm coordination suggests that additional neurotransmitters may also be involved in arm swing changes in PD.	25502948
Communicable Diseases, Inflammation, Traumatic injury	Altered Intercellular Communication	Increased local skin temperature is a classic sign of wound infection, repetitive trauma, and deep inflammation.	25502971
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Comparison of prostate cancer gene 3 score, prostate health index and percentage free prostate-specific antigen for differentiating histological inflammation from prostate cancer and other non-neoplastic alterations of the prostate at initial biopsy.	25503144
Stomach Carcinoma	Altered Intercellular Communication	Clinical significance of an inflammation-based prognostic system for gastric cancer patients with a preoperative normal serum level of carcinoembryonic antigen.	25503152
Primary malignant neoplasm	Altered Intercellular Communication	On the other hand, the GPS has been established as a valuable inflammation-based prognostic system for cancer patients.	25503152
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The molecular mechanism underlying the development of colorectal cancer (CRC) is not yet fully-understood, but there is evidence that inflammation plays a key role.	25503158
Inflammation	Altered Intercellular Communication	Radiation recall refers to chemotherapy-triggered inflammation in healthy areas previously exposed to irradiation.	25503169
Inflammation	Altered Intercellular Communication	MMP-8 could play an important role in the inflammation processes during the development of periapical lesions.	25503342
Hemorrhagic, Inflammation, Endothelial dysfunction, Ischemic stroke	Altered Intercellular Communication	Our results suggest that NURR1 upregulation by r-tPA during ischemic stroke is associated with endothelial dysfunction and inflammation and the enhancement of hemorrhagic complications associated to thrombolysis.	25503547
glycation, Inflammation, Chronic disease	Altered Intercellular Communication	A receptor for advanced glycation end products (RAGE) and its ligand high mobility group box 1 (HMGB1) protein has been linked to several chronic diseases, and acts as a trigger for inflammation signaling.	25503556
Malaria, Falciparum, Communicable Diseases, Inflammation	Altered Intercellular Communication	Our findings underscore the complex role of inflammation during infection with P. falciparum, and suggest a potential pathogenic role for IL-8 and IP-10.	25503583
Cessation of life, Hepatic inflammation	Altered Intercellular Communication	Waterborne exposure of zebrafish in cage water containing AA (300 ppm) resulted in acute death within 26 h along with elevation of body weight, blood glucose, triglyceride, and hepatic inflammation.	25503949
Herpes, Angiolymphoid hyperplasia, Hyponatremia	Altered Intercellular Communication	We hypothesize that non-osmotic release of plasma antidiuretic hormone is a cause of hyponatraemia in human herpes virus-8-associated multicentric Castleman's disease and that relapsing and remitting hyponatraemia could be correlated with plasma human herpes virus-8 viral load.	25504830
Refractory anemias, Inflammation, Rheumatoid Arthritis, Atherosclerosis	Altered Intercellular Communication	Systemic inflammation and insulin resistance (IR) are linked, yet the determinants of IR and its impact on atherosclerosis in rheumatoid arthritis (RA) are incompletely understood.	25504899
Inflammation, Malnutrition, Anemia	Altered Intercellular Communication	A cohort of 199 fit hemodialysis patients free of overt inflammation and malnutrition were treated for anemia with parenteral iron-sucrose and an erythropoesis-stimulating agent (darbepoetin), in keeping with current clinical guidelines.	25506921
Gastrointestinal inflammation	Altered Intercellular Communication	Calprotectin is a cytoplasmatic protein of neutrophilic granulocytes and it is an established marker for the assessment of localized intestinal inflammation.	25509200
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Chronic inflammation and immunosuppressive treatment are risk factors for epithelial and lymphoid malignancies.	25509562
Inflammation, Chronic heart failure, Ventricular Dysfunction	Altered Intercellular Communication	[Biomarkers of iron metabolism and inflammation in patients with chronic heart failure and various types of left ventricular dysfunction].	25510083
Inflammation, Perforation (observation)	Altered Intercellular Communication	Therefore a formal term from the moment of perforation can not be the index of degree of inflammation (bacterial contamination) of peritoneum.	25510091
Weight Gain, Inflammation	Altered Intercellular Communication	Inflammation and weight gain in reproductive-aged women.	25510294
Inflammation, Synovitis, Refractory anemias, Edema of bone marrow, Rheumatoid Arthritis, Tenosynovitis	Altered Intercellular Communication	Magnetic resonance imaging (MRI) is a sensitive method to detect inflammation in rheumatoid arthritis (RA), visualizing synovitis, bone marrow edema, and tenosynovitis.	25510520
Inflammation	Altered Intercellular Communication	Vitamin D is associated with skeletal muscle physiology and function and may play a role in intramuscular inflammation, possibly via the vitamin D receptor (VDR).	25510525
Inflammation, Actinomycosis	Altered Intercellular Communication	Endometrial/endocervical specimens showed marked chronic inflammation with sulfur granules, with a colony of filamentous organisms consistent with Actinomyces infection.	25510706
Inflammation, Intracranial Aneurysm, Rupture	Altered Intercellular Communication	Inflammation plays a key role in formation and rupture of intracranial aneurysms.	25510828
vascular inflammations, Intracranial Aneurysm	Altered Intercellular Communication	Because hepatocyte growth factor (HGF) protects against vascular inflammation, we sought to assess the role of endogenous HGF in the pathogenesis of intracranial aneurysms.	25510828
Inflammation, Aneurysm, Ruptured	Altered Intercellular Communication	HGF signaling through c-Met may decrease inflammation in endothelial cells and protect against intracranial aneurysm rupture.	25510828
Hyperglycemia, Inflammation	Altered Intercellular Communication	In PBMC of T2DM without glycemic target achievement, there is an activation of the UPR and of the ER apoptosis, which may be related to the chronic exposure to hyperglycemia, to the augmented inflammation, and to the augmented oxidative stress, without a corresponding Nrf2/ARE defense activation.	25511473
Inflammation, Immune-mediated, Nerve Degeneration	Altered Intercellular Communication	Multiple Sclerosis (MS) is an immune-mediated disease of the Central Nervous System with two major underlying etiopathogenic processes: inflammation and neurodegeneration.	25512202
Inflammation, HIV, GDC Comorbidity Terminology	Altered Intercellular Communication	Elite controllers spontaneously suppress human immunodeficiency virus (HIV) viremia but also demonstrate chronic inflammation that may increase risk of comorbid conditions.	25512624
Metabolic Syndrome X	Altered Intercellular Communication	Walk-run training improves the anti-inflammation properties of high-density lipoprotein in patients with metabolic syndrome.	25514103
ETV3 wt Allele	Altered Intercellular Communication	This study was designed to investigate whether walk/run training without any specific diet could enhance anti-inflammation capacity of HDL from MetS patients.	25514103
ETV3 wt Allele	Altered Intercellular Communication	The anti-inflammation capacities of HDL3 (HDL subfractions) from MetS patients with or without exercise were investigated by co-incubating with TNF- a-injured endothelial cells in vitro.	25514103
ETV3 wt Allele	Altered Intercellular Communication	Walk/run training leads to a significant improvement in HDL anti-inflammation capacity in subjects with MetS without restricted diet, the mechanism underlying which at least partially is due to increased PON1 activity in HDL, NO production, and eNOS expression in endothelial cells.	25514103
eosinophil, Asthma	Altered Intercellular Communication	These findings support the requirement of CLC3 in the activation and migration of human blood eosinophils and may provide a potential novel therapeutic target to regulate eosinophil hyperactivity in allergic airway inflammation in asthma.	25514499
ACSM3 gene, Subarachnoid Hemorrhage, Aneurysmal, Hypothalamo-Hypophyseal System	Altered Intercellular Communication	Impaired systemic hormonal activity caused by hypothalamic and pituitary injury may contribute to neuropsychologic disturbances and poor quality of life after aneurysmal subarachnoid hemorrhage (SAH).	25514615
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation with central caseous necrosis surrounded by edematous brain with reactive gliosis and acid-fast bacilli were revealed on histopathologic analysis.	25515023
Inflammation, Specimen Type - Fistula	Altered Intercellular Communication	Immunohistochemical staining revealed decreases in membrane E-cadherin and b-catenin and a significant increase in the cytoplasmic fraction, depending on the severity of inflammation in the fistula tissue.	25515126
Inflammation, Pancreatic carcinoma	Altered Intercellular Communication	However, the possible relationship between diet-related inflammation and the risk of pancreatic cancer has not yet been investigated.	25515552
Inflammation, Neoplasms	Altered Intercellular Communication	The neutrophil-to-lymphocyte ratio (NLR), a marker of host inflammation, has been associated with poor outcome in several solid tumors.	25515657
Malignant neoplasm of esophagus	Altered Intercellular Communication	The inflammation-based modified Glasgow prognostic score (mGPS) has been shown to be a prognostic factor for esophageal cancer, but its changes in relation to neoadjuvant chemotherapy (NAC) have never been discussed.	25515972
Inflammation	Altered Intercellular Communication	The findings suggest that coagulation leads to functional decline and mortality s that inflammation does not explain.	25516032
Degenerative disorder, Neoplasms	Altered Intercellular Communication	These concepts are relevant to issues in modern human longevity, including inflammation-induced neoplasia and degenerative diseases of the elderly, which are a legacy of human evolution.	25516618
Degenerative disorder, Neoplasms	Altered Intercellular Communication	The hypothesis that we present provides new bases for modern medical problems, such as inflammation-induced neoplasia and degenerative diseases of the elderly.	25516618
Inflammation, Acute myocardial infarction	Altered Intercellular Communication	Inflammation in the setting of acute myocardial infarction (MI) has been linked to risk stratification; however, the release kinetics of inflammatory biomarkers in patients with acute MI has been difficult to establish.	25516775
Airway Obstruction, Pulmonary Emphysema, Bronchitis	Altered Intercellular Communication	Among others, the identified genes are also involved in emphysema, airway obstruction, and bronchial inflammation.	25517131
Inflammation, Medial degeneration	Altered Intercellular Communication	We previously showed that the metabolically active areas displayed adventitial inflammation, medial degeneration and molecular alterations prefacing wall rupture.	25517227
Inflammation, Acute appendicitis NOS (disorder)	Altered Intercellular Communication	Correlation between the serum and tissue levels of oxidative stress markers and the extent of inflammation in acute appendicitis.	25518019
IL13 gene, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Allergic rhinitis is a disease that affects the upper airways and causes inflammation of the nasal mucosa and it is mediated by IgE antibodies produced after sensitization to environmental allergens.	25518031
Ulcerative Colitis	Altered Intercellular Communication	Sixty-two patients with ulcerative colitis underwent colonoscopy for classification of mucosal inflammation [Mayo endoscopic subscore].	25518057
Vasculitis	Altered Intercellular Communication	Its anti-inflammation effects suppress vascular wall inflammation of KD at acute phase.	25518411
Inflammation	Altered Intercellular Communication	It was found that the number of lymphocytes and neutrophils located in the lamina and intraepithelial increases, which is associated with the degree of inflammation.	25518455
Inflammation	Altered Intercellular Communication	Intensity of leukocyte infiltration is directly correlated with the increased prevalence of inflammation.	25518455
Inflammation	Altered Intercellular Communication	Cellular composition of the infiltrate is an objective characteristic of chronic inflammation in the gastric mucosa.	25518455
Inflammation, senile, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Problems with insulin secretion lead to oxidative stress, chronic inflammation, and type II diabetes, which can be regarded as one of the forms of senile phenoptosis.	25519059
Inflammation, Neoplasms, Colon diverticulum anatomic structure, Hemorrhoids, CTCAE 5.0, Colonic Polyps	Altered Intercellular Communication	Data collected were patient demographic and significant colonoscopy findings such as the presence of hemorrhoids, colonic polyps, colonic diverticula, inflammation, and tumor mass.	25520108
Crohn Disease, Inflammation, Ulcerative Colitis, Cryptitis	Altered Intercellular Communication	CLE findings in patients with Crohn's disease, showed significantly more discontinuous inflammation (87.5 % vs. 5.1 %), focal cryptitis (75.0 % vs. 12.8 %), and discontinuous crypt architectural abnormality (87.5 % vs. 10.3 %) than in ulcerative colitis (P < 0.0001).	25521573
methyldopa, Inflammation, Atrophic	Altered Intercellular Communication	Whether this physiologic deviation that occurs in AMD is related to atrophy, inflammation, or changes in autoregulatory factors or growth factors remains to be determined.	25521616
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	Histological changes, including chronic inflammation, activity, atrophy, and intestinal metaplasia, were evaluated using the updated Sydney system.	25521735
Inflammation	Altered Intercellular Communication	Chronic inflammation scores were improved after eradication at both the lesser (mean scores +- SD: before eradication, 2.9+-0.5; 1 year after, 2.3+-0.4; 3 years, 1.8+-0.3; 5 years, 1.5+-0.3; 7 years, 1.3+-0.3; and 9 years, 1.0+-0.3) and greater curvatures (before, 2.9+-0.4; 1 year after, 1.9+-0.3; 3 years, 1.4+-0.4; 5 years, 1.3+-0.3; 7 years, 1.1+-0.2; and 9 years, 0.6+-0.3).	25521735
Inflammation, Atrophic	Altered Intercellular Communication	Atrophy scores improved more quickly after eradication than chronic inflammation scores at both the lesser (before, 2.4+-0.5; 1 year after, 1.8+-0.4; 3 years, 0.8+-0.3; 5 years, 0.3+-0.1; 7 years, 0.0; and 9 years, 0.0) and greater curvatures (before, 2.2+-0.4; 1 year after, 1.3+-0.3; 3 years, 0.5+-0.3; 5 years, 0.0; 7 years, 0.0; and 9 years, 0.0).	25521735
Alzheimers Disease", Periodontitis, Inflammation, Data types - Address	Altered Intercellular Communication	Periodontitis and Alzheimer disease (AD) are associated with systemic inflammation.	25522313
Chronic Kidney Diseases	Altered Intercellular Communication	Diagnostic validation and prognostic significance of the Malnutrition-Inflammation Score in nondialyzed chronic kidney disease patients.	25523451
Inflammation, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	Malnutrition and inflammation are highly prevalent and intimately linked conditions in chronic kidney disease (CKD) patients that lead to a state of protein-energy wasting (PEW), the severity of which can be assessed by the Malnutrition-Inflammation Score (MIS).	25523451
Inflammation, Malnutrition	Altered Intercellular Communication	A structural equation model with two latent variables (assessing simultaneously malnutrition and inflammation factors) demonstrated good fit to the observed data.	25523451
Psoriatic Juvenile Idiopathic Arthritis, Diamond-Blackfan Anemia 1, Certified Midwife	Altered Intercellular Communication	To investigate whether the serum levels of inflammation-related cytokines might be different between the healthy individuals and the psoriatic patients diagnosed of three varied Chinese medicine (CM) syndromes [blood-stasis syndrome (BSS), blood-dryness syndrome (BDS) and wind-heat syndrome (WHS)].	25523599
Inflammation, Extravasation, Chronic Spontaneous Urticaria	Altered Intercellular Communication	As Th2-initiating cytokines play a role in mast cell activation, inflammation and vascular leakage in CSU, these findings may also have therapeutic implications.	25523947
Inflammation, Rheumatoid Arthritis, Cardiovascular system	Altered Intercellular Communication	Serum amyloid A as a marker of persistent inflammation and an indicator of cardiovascular and renal involvement in patients with rheumatoid arthritis.	25525305
Inflammation	Altered Intercellular Communication	Recurrent assessment of SAA may facilitate searching patients with persistent inflammation and risk of extra-articular complications.	25525305
Calcinosis, Aortic valve structure	Altered Intercellular Communication	Early aortic valve inflammation precedes calcification: a longitudinal FDG-PET/CT study.	25525744
Inflammation, Calcinosis	Altered Intercellular Communication	Recent data shows a relationship between aortic valve (AV) inflammation and calcification.	25525744
Endocarditis	Altered Intercellular Communication	However, direct evidence linking early valve inflammation (prior to hemodynamic compromise) to subsequent calcium (Ca) deposition is lacking in humans.	25525744
Inflammation	Altered Intercellular Communication	We sought to test the hypothesis whether local AV inflammation predisposes to subsequent AV Ca deposition.	25525744
Inflammation	Altered Intercellular Communication	AV inflammation was determined by measuring FDG uptake (maximum standardized uptake value, SUVmax) within the AV on baseline PET/CT.	25525744
Inflammation, doxorubicin/vincristine protocol, Calcinosis	Altered Intercellular Communication	Moreover, AV inflammation (AV SUVmax) independently predicted subsequent calcification after adjusting for cardiovascular risk factors [OR (95%CI): 4.99 (1.30-19.15), p = 0.02].	25525744
Sclerosis, Inflammation	Altered Intercellular Communication	The findings suggest that early AV inflammation may predispose to AV sclerosis.	25525744
Inflammation, Hydrocephalus	Altered Intercellular Communication	We report the unique case of a 9-month-old infant with progressive internal hydrocephalus of unknown origin and developmental delay due to a history of>200 days of inflammation of the central nervous system.	25525814
Inflammation, Hydrocephalus, Ureaplasma	Altered Intercellular Communication	In preterm infants, in particular, internal hydrocephalus of unknown origin and sustained CSF inflammation are highly suggestive of Ureaplasma meningitis.	25525814
Vitritis, Vitreous inflammatory cells	Altered Intercellular Communication	A retrospective chart review was performed of keratoprosthesis recipients at Massachusetts Eye and Ear Infirmary, from January 2000 to August 2013, for demographic data, indication(s) for surgery, timing and presentation of vitreous inflammation, and best-corrected visual acuity at baseline, on presentation, and after resolution of vitritis.	25526075
Orbital Pseudotumor	Altered Intercellular Communication	Twenty-three (23 eyes) of 346 patients developed idiopathic vitreous inflammation after keratoprosthesis implantation.	25526075
Unknown (origin) (qualifier value), Inflammation, Infectious Endophthalmitis, Pain Distress Question	Altered Intercellular Communication	However, idiopathic vitritis after keratoprosthesis can also mimic infectious endophthalmitis with pain and external signs of inflammation.	25526075
Inflammation	Altered Intercellular Communication	Vitritis may be a part of a common pathway of chronic inflammation after keratoprosthesis.	25526075
Necrotizing granulomatous inflammation	Altered Intercellular Communication	For each patient, other etiologies of nonnecrotizing granulomatous inflammation were excluded.	25526097
Inflammation, Obesity	Altered Intercellular Communication	Diet-induced obesity can induce low-level inflammation and insulin resistance.	25526310
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Interleukin-1b (IL-1b) is one of the key proinflammatory cytokines that contributes to the generation of insulin resistance and diabetes, but the mechanisms that regulate obesity-driven inflammation are ill defined.	25526310
Hepatitis, Neoplasms, Fibrosis Assessment, Somatic mutation, Liver Cirrhosis	Altered Intercellular Communication	Here we sequence tumour and matching control sample pairs of a large cohort of 103 ICC patients in China, resulting in the identification of an ICC-specific somatic mutational signature that is associated with liver inflammation, fibrosis and cirrhosis.	25526346
Inflammation, Prostate Cancer Outcomes Study	Altered Intercellular Communication	The sirtuin 1 level, which is associated with inflammation, the immune system and insulin metabolism, was higher in the PCOS patients than in the healthy controls.	25526506
Malignant tumor of colon, Inflammation	Altered Intercellular Communication	The ethiology of colon cancer is largely dependent on inflammation driven oxidative stress.	25526641
Acute Lung Injury, Inflammation, Alveolar	Altered Intercellular Communication	Acute lung injury (ALI) is characterized by alveolar injury and uncontrolled inflammation.	25526715
Adenoma, Chromophobe, Pituitary Adenoma	Altered Intercellular Communication	Further evaluations including hormonal screening revealed a clinically non-functioning pituitary adenoma (chromophobe adenoma).	25526868
Airway structure, Asthma	Altered Intercellular Communication	Occupational exposures, smoking and airway inflammation in refractory asthma.	25526871
Inflammation, polychondritis	Altered Intercellular Communication	Relapsing polychondritis is a rare disease characterised by inflammation of cartilaginous and proteoglycan rich structures.	25527201
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	AGEs have been associated with insulin resistance, oxidative stress, and chronic inflammation in patients with diabetes.	25527756
Fibrous, Inflammation, Calcified (qualifier)	Altered Intercellular Communication	The essence of the disease, whose etiology and pathogenesis remains unclear, is the fibrous tissue infiltration and diffuse inflammation with focal calcifications.	25527808
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	In addition, several pathognomonic features of KS, not related to skin fragility such as aging, inflammation and cancer predisposition have been strongly associated with oxidative stress.	25528446
vascular inflammations	Altered Intercellular Communication	Vascular inflammation in metabolically abnormal but normal-weight and metabolically healthy obese individuals analyzed with 18F-fluorodeoxyglucose positron emission tomography.	25529544
vascular inflammations, Dental Plaque	Altered Intercellular Communication	(18)F-fluorodeoxyglucose (FDG) positron emission tomography is a useful imaging technique for detecting vascular inflammation that may reflect plaque vulnerability.	25529544
vascular inflammations	Altered Intercellular Communication	Therefore, we analyzed which body size phenotypes cause the increased vascular inflammation using FDG positron emission tomography.	25529544
vascular inflammations, Units Of Measure - Siemens	Altered Intercellular Communication	In conclusion, the present study suggests that unique subsets of body size phenotype, such as MHO or metabolically abnormal but normal weight, may have distinct effects on vascular inflammation.	25529544
Inflammation, Asthma attack, Exacerbation	Altered Intercellular Communication	These results suggest that IL-8 may be more important in airway and systemic inflammation in COPD exacerbations than in asthma attacks.	25530067
Inflammation, Prostate carcinoma	Altered Intercellular Communication	A total of 274 patients (58.8%) had prostate cancer, 88 patients (18.9%) inflammation, and 104 patients (22.3%) had benign pathology.	25530382
Inflammation	Altered Intercellular Communication	The combined case finding strategy identified 3160 patients with sIBM compatible ICD-10 codes, and a largely overlapping cohort of 500 patients having muscle biopsies encoded with inflammation.	25530508
Extrinsic allergic alveolitis, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Fibrocytes contribute to inflammation and fibrosis in chronic hypersensitivity pneumonitis through paracrine effects.	25531246
Extrinsic allergic alveolitis, Pneumonitis	Altered Intercellular Communication	Hypersensitivity pneumonitis (HP) represents a lung inflammation provoked by exposure to a variety of antigens.	25531246
Inflammation, metabolic disturbance	Altered Intercellular Communication	[Associations between basic indicators of inflammation and metabolic disturbances].	25531700
Inflammation, Complications of Diabetes Mellitus, metabolic disturbance	Altered Intercellular Communication	Inflammation is involved in initiation and progression of diabetic complications related to cell damage of tissues, especially endothelial cells, and deepening of metabolic disturbances.	25531700
Hepatosplenomegaly, Exanthema, Fever, CTCAE, Arthralgia, Arthritis, Juvenile-Onset Still Disease, Myalgia, CTCAE 5	Altered Intercellular Communication	Adult-onset Still's disease is a rare inflammatory condition of unknown origin characterized by high spiking fever, arthralgia, arthritis, myalgia, salmon-colored evanescent rash, and hepatosplenomegaly.	25532568
Inflammation, Carcinogenesis	Altered Intercellular Communication	Unique database study linking gingival inflammation and smoking in carcinogenesis.	25533098
Gingivitis, Carcinogenesis, Primary malignant neoplasm	Altered Intercellular Communication	We investigated statistical association between gingival inflammation and cancer in a group of patients followed up for 26 years with the hypothesis that gingival inflammation affects carcinogenesis.	25533098
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Gingival index, marker of gingival inflammation, was higher in the cancer group than in subjects with no cancer.	25533098
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Hence, our present findings showed that together with smoking, gingival inflammation indeed associated with the incidence of cancer in this cohort.	25533098
Hepatitis	Altered Intercellular Communication	Liver inflammation correlated with mRNA expression of genes regulating ketolysis in the liver (Spearman correlation 0.379-0.388, P < 0.0006 for ACAT1, ACSS2 and BDH1).	25533197
Ichthyosis Bullosa of Siemens, Gastrointestinal inflammation	Altered Intercellular Communication	Low-grade intestinal inflammation plays a role in the pathophysiology of IBS.	25533646
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Accumulating evidence indicates that systemic inflammation response is associated with the prognosis of various cancers.	25533822
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	The predictive role of renal function and systemic inflammation on the onset of de novo atrial fibrillation after cardiac surgery.	25534011
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Both systemic inflammation and oxidative stress play a role in the initiation of postoperative atrial fibrillation after cardiac surgery.	25534306
Inflammation, Attack behavior	Altered Intercellular Communication	The child had a sustained remission of febrile attacks and inflammation after transplant, and during a 5-year follow-up period, psychomotor and neurologic development were normal, without signs of underlying disease or late transplant-related effects.	25535259
Anxiety, CTCAE 3.0, Inflammation, error	Altered Intercellular Communication	In comparison, basal pulse primarily depended on general physiological parameters and reduced cholinergic control over anxiety and inflammation, together indicating that consistent exposure to terror threats ignites fear-induced exacerbation of preexisting neuro-immune risks of all-cause mortality.	25535364
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Patients with CD are twice as likely as UC patients to experience EIM, and more extensive distribution of inflammation in UC increases the risk of EIM.	25535653
Inflammation, Fatigue	Altered Intercellular Communication	Sicca symptoms of the mouth and eyes, salivary gland capacity, tear secretion, minor salivary gland inflammation, serum autoantibodies, and fatigue were also investigated.	25535773
Inflammation, Dyssomnias	Altered Intercellular Communication	Sleep disturbance has been associated with inflammation and cytokine activity, and we previously described genetic associations between cytokine polymorphisms and sleep maintenance and duration among adults with HIV/AIDS.	25535857
Inflammation, Dyssomnias	Altered Intercellular Communication	This study strengthens the evidence for an association between inflammation and sleep disturbance, particularly self-report of habitual SOI.	25535857
Inflammation, Sleep Apnea, CTCAE	Altered Intercellular Communication	Gender differences in the association of sleep apnea and inflammation.	25535861
Inflammation, Sleep Apnea, CTCAE	Altered Intercellular Communication	Over the last 15years, many studies have established an association of sleep apnea with inflammation and metabolic aberrations.	25535861
Inflammation, ASF1A gene, Erosion of bone	Altered Intercellular Communication	Incidence and severity of CIA and histological parameters (inflammation, cartilage degradation, and bone erosion) were not different in WT and CRAMP-/- mice.	25535966
Inflammation, trauma to the abdomen, Intra-abdominal	Altered Intercellular Communication	Excessive systemic inflammation after abdominal injury or intra-abdominal sepsis is associated with poor outcomes.	25536308
Decompensation, Inflammation, Liver Dysfunction	Altered Intercellular Communication	However, significantly lower levels were observed during admission for acute decompensation suggesting an impact of systemic inflammation or liver dysfunction on 25(OH)D levels.	25536647
Cerebral Amyloid Angiopathy, "Alzheimers Disease", Inflammation	Altered Intercellular Communication	Prodromal Alzheimer's disease presenting as cerebral amyloid angiopathy-related inflammation with spontaneous amyloid-related imaging abnormalities and high cerebrospinal fluid anti-Ab autoantibodies.	25537009
Inflammation, NRG1 protein, human, "Alzheimers Disease", Data types - Address, Vasculitis, CTCAE	Altered Intercellular Communication	Cerebral amyloid angiopathy-related inflammation (CAA-ri), a rare form of vasculitis associated with amyloid-b (Ab) deposition in vessel walls, has been proposed as a spontaneous human model of the amyloid-related imaging abnormalities (ARIA) occurring after anti-Ab immunotherapy for the treatment of Alzheimer's disease (AD).	25537009
Inflammation, Fatty degeneration, Acute and chronic inflammation	Altered Intercellular Communication	Initial biopsies demonstrated steatosis 77 %, lobular inflammation 39 %, and chronic portal inflammation 56 %.	25537957
Inflammation, Acute and chronic inflammation, Fatty degeneration, Steatohepatitis	Altered Intercellular Communication	On post-bariatric biopsy, steatosis resolved in 75 %, lobular inflammation resolved in 75 %, chronic portal inflammation resolved in 49 %, and steatohepatitis resolved in 90 %.	25537957
Inflammation, Prostate carcinoma	Altered Intercellular Communication	The neutrophil-lymphocyte ratio (NLR), proposed as an indicator of cancer-related inflammation, has known prognostic value in prostate cancer.	25538172
Communicable Diseases, Inflammation	Altered Intercellular Communication	Evidence of central nervous system inflammation in the absence of direct infection suggests an immune-mediated pathophysiology.	25538215
Cardiovascular system	Altered Intercellular Communication	Pentraxin-3 (PTX3) is an inflammatory marker thought to be more specific to cardiovascular inflammation than C-reactive protein (CRP).	25538378
Gastrointestinal inflammation, Cystic Fibrosis	Altered Intercellular Communication	Intestinal inflammation and impact on growth in children with cystic fibrosis.	25539196
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	Faecal samples for markers of intestinal inflammation, calprotectin, S100A12, and osteoprotegerin, were collected from children with CF, healthy controls (HCs), and Crohn disease (CD).	25539196
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	The pattern of intestinal inflammation in CF is unique and distinct from inflammatory bowel disease, with elevated faecal calprotectin but normal faecal S100A12 and osteoprotegerin concentrations.	25539196
Gastrointestinal inflammation	Altered Intercellular Communication	The severity of intestinal inflammation, based on faecal calprotectin, significantly correlates with poor growth.	25539196
Airway structure, ARCN1 gene	Altered Intercellular Communication	Airway inflammation and tiotropium treatment in stable COPD patients.	25539549
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults.	25539758
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The study examines the association of neighborhood socioeconomic deprivation and metabolic syndrome with inflammation.	25539758
Inflammation, Lung Diseases, Interstitial	Altered Intercellular Communication	TREM-1 and TLR's likely affect patterns of inflammation in various interstitial lung diseases.	25540922
Tissue damage, Inflammation	Altered Intercellular Communication	Brain lesions observed in patients with CDR, as well as the higher density of cells immunostained with anti-IL17 at these sites, suggest that this cytokine was increasing local inflammation with subsequent tissue damage due to inflammation.	25541242
Esophagitis	Altered Intercellular Communication	Furthermore, the higher density of mast cells in the esophagus and large bowel of these subjects suggests that these cells might play a major role in esophageal and intestinal inflammation.	25541242
Autoimmune Diseases, Communicable Diseases, Inflammation	Altered Intercellular Communication	Apoptosis of the lymphocytes plays an essential role in the regulation of inflammatory/immune responses and its abnormalities may contribute to a chronic infection, persistent inflammation and autoimmunity.	25541498
Diabetic Nephropathy, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	The role of inflammation in both diabetes and diabetic kidney disease (DKD) is becoming more widely accepted.	25542095
Inflammation, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease is associated with malnutrition and inflammation.	25542415
Inflammation, Immunocompromised Host	Altered Intercellular Communication	Impact of inflammation and concomitant glucocorticoid administration on plasma concentration of triazole antifungals in immunocompromised patients.	25542532
Schizophrenia, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Our findings provide further evidence that measurement of total and differential WBC counts may be germane to the clinical care of patients with schizophrenia and related disorders, and support an association between inflammation and cardiovascular disease risk in these patients.	25542737
Inflammation	Altered Intercellular Communication	We explored the possibility that PSF is related to systemic inflammation by investigating polymorphisms in 2 genes that affect the immune response.	25542762
Gynecologic, Inflammation, Endometriosis	Altered Intercellular Communication	Endometriosis is a chronic gynaecological disorder that is accompanied by inflammation and oxidative stress.	25543526
Inflammation, Endometriosis	Altered Intercellular Communication	We also measured markers of inflammation and oxidative stress in women with endometriosis.	25543526
Intravascular Route of Drug Administration, Inflammation, Pulmonary Infarction, Vasculitis, CTCAE	Altered Intercellular Communication	Within affected lung, associated histopathologic changes included occlusive intravascular or perivascular inflammation (89%), intravascular fibrous response (56%), microthrombus formation (44%), vasculitis (28%), and/or pulmonary microinfarction (28%).	25543660
Degenerative polyarthritis, Arthralgia, Arthritis	Altered Intercellular Communication	To evaluate the ability of the macrophage markers CD163 and CD14 to predict different osteoarthritis (OA) phenotypes defined by severity of joint inflammation, radiographic features and progression, and joint pain.	25544994
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	These data support the central role of inflammation as a determinant of OA severity, progression risk, and clinical symptoms, and they suggest a means of readily identifying a subset of patients with an active inflammatory state and worse prognosis.	25544994
Inflammation, In Cerebrospinal Fluid	Altered Intercellular Communication	Further exploration of the mechanistic explanation is needed, but we suggest this may be from a combination of obstruction of cerebrospinal fluid pathways by blood products and inflammation in the choroid plexus resulting in increased cerebrospinal fluid production.	25545809
Colorectal Carcinoma, Gastrointestinal inflammation	Altered Intercellular Communication	Toll-like receptor (TLR) 9 plays a role in intestinal inflammation that, in turn, is related to the tumorigenesis of colorectal cancer.	25546690
Communicable Diseases, Inflammation, Lower Urinary Tract Symptoms, Pain Distress Question	Altered Intercellular Communication	Patients with LUTS (Lower Urinary Tract Symtoms--inflammation, infection, pain) were excluded.	25546927
Inflammation, Gastroenteritis	Altered Intercellular Communication	Eosinophilic gastroenteritis is a rare condition where eosinophilic inflammation occurs in the gastrointestinal tract in the absence of secondary causes.	25547198
Communicable Diseases, Inflammation	Altered Intercellular Communication	Neutrophils are rapidly recruited in response to local tissue infection or inflammation.	25548073
Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Inflammation-based scoring is a useful prognostic predictor of pulmonary resection for elderly patients with clinical stage I non-small-cell lung cancer.	25548132
Inflammation, Anemia, Sickle Cell, SLC22A5 gene	Altered Intercellular Communication	Previous studies on the role of inflammation in the pathophysiology of sickle cell disease (SCD) suggested that the CCR5D32 allele, which is responsible for the production of truncated C-C chemokine receptor type 5 (CCR5), could confer a selective advantage on patients with SCD because it leads to a less efficient Th1 response.	25548430
Septic Shock	Altered Intercellular Communication	Inflammation markers were decreased after the treatment of septic shock in both groups (p<0.05).	25549485
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	A role for inflammation in the atrial remodeling as well as development and recurrence of AF is known.	25549592
Inflammation, Carcinogenesis, Colorectal Carcinoma	Altered Intercellular Communication	Inflammation is a process central to carcinogenesis and in particular to colorectal cancer (CRC).	25549833
Autoimmune Diseases, Inflammation, polychondritis	Altered Intercellular Communication	Relapsing polychondritis is a rare autoimmune disease causing inflammation in cartilaginous structures and other tissues throughout the body.	25550527
Inflammation, Neoplasms, Malignant Neoplasms	Altered Intercellular Communication	Inflammation and tumor immunology are important in the prognosis of various cancers.	25550569
Inflammation, Fibrosis Assessment, Stenosis	Altered Intercellular Communication	Strictures develop as a consequence of tissue remodelling and fibrosis due to chronic inflammation.	25550777
Autoimmune Diseases, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The interleukin-1 receptor associated kinases 1 (IRAK1) is a down stream effector molecule of the toll like receptor (TLR) signaling pathway, which is involved in inflammation, autoimmunity and cancer.	25550857
Granuloma, Granulomatous inflammation, Sarcoidosis, Squamous cell carcinoma, Silicosis, Adenocarcinoma of lung (disorder), Pneumonia, Viral, Hyperplasia	Altered Intercellular Communication	The first patient had squamous cell carcinoma in the left upper lobe of the lung with surrounding necrotizing granulomas and concurrent with silicosis and granulomatous inflammation in the lymph nodes; the second presented with symptoms of viral pneumonia, which was pathologically diagnosed as a lung adenocarcinoma, stage IA, concurrent with sarcoidosis involving the lymph nodes; the last case was diagnosed as squamous cell carcinoma in the right upper lobe of the lung, but lymph nodes showed reactive hyperplasia.	25550877
Inflammation	Altered Intercellular Communication	Chronic and acute inflammation can be found, and diseases that impair the immune system and pregnancy have been associated with this condition.	25551590
Malignant Neoplasms	Altered Intercellular Communication	Non-steroidal anti-inflammatory drugs use is associated with reduced risk of inflammation-associated cancers: NIH-AARP study.	25551641
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Chronic inflammation has been linked to cancers, and use of non-steroidal anti-inflammatory drugs (NSAIDs) has been associated with reduced risk of several cancers.	25551641
vascular inflammations, Platelet aggregation measurement	Altered Intercellular Communication	Mean platelet volume (MPV) is a determinant of platelet functionality and increased MPV is associated with an increased risk of vascular inflammation.	25552162
Inflammation, Cholesteatoma	Altered Intercellular Communication	Additional control of inflammation was performed in 2 patients at second-stage surgery for cavity problem and cholesteatoma, respectively.	25552887
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Inflammation is thought to be involved in the pathogenesis of obstructive sleep apnea syndrome (OSAS).	25553801
Inflammation	Altered Intercellular Communication	Declines in inflammation predict greater white matter microstructure in older adults.	25554492
Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	Protracted systemic inflammation has been associated with adverse effects on cognition and brain structure and may accelerate neurodegenerative disease processes; however, it is less clear whether changes in inflammation are associated with brain structure.	25554492
Inflammation	Altered Intercellular Communication	These include genes involved in neurogenesis (NPDC1) and inflammation (HERC5), as well as alcoholism-associated genes ADCY9, CKM, and PHOX2A.	25555412
Inflammation	Altered Intercellular Communication	The pathophysiology is poorly understood, but low-grade systemic inflammation has been suggested as an important component.	25555530
Inflammation, Chronic Fatigue Syndrome	Altered Intercellular Communication	Adolescent CFS patients are burdened by symptoms that might suggest low-grade systemic inflammation, but plasma levels of individual cytokines as well as cytokine network measures were not different from healthy controls, and there were no associations between symptoms and cytokine expression in the CFS group.	25555530
Communicable Diseases, Inflammation, Tonsillitis	Altered Intercellular Communication	Chronic tonsillitis is the persistent inflammation of the tonsillar tissue that occurs due to recurrent, acute or subclinical infection.	25555639
Tonsillitis, Hypertrophy	Altered Intercellular Communication	The recurrent and chronic inflammation of palatine tonsils sometimes results in hypertrophy.	25555639
Inflammation, Thrombosis	Altered Intercellular Communication	Activated platelets play a key role in inflammation and atherothrombosis, with mean platelet volume (MPV) is an early marker of platelet activation.	25556499
Inflammation, Ischemic stroke	Altered Intercellular Communication	Recombinant T-cell receptor ligand RTL1000 limits inflammation and decreases infarct size after experimental ischemic stroke in middle-aged mice.	25556831
Ischemic stroke	Altered Intercellular Communication	These findings suggest that RTL1000 protects against ischemic stroke in middle-aged male mice by limiting post-ischemic inflammation.	25556831
Hyperammonemia, Inflammation, Impaired cognition	Altered Intercellular Communication	Our observations lead to the hypothesis that oxidative stress and increased peroxynitrite formation would mediate the synergistic effects of hyperammonemia and inflammation on cognitive and motor impairment in MHE.	25557123
Inflammation, muscle mass	Altered Intercellular Communication	Ageing is also associated with low grade inflammation (LGI), which has been negatively correlated with muscle mass and strength.	25557160
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	TGF-b-activated protein kinase 1 (TAK1) is a critical mediator in inflammation, immune response and cancer development.	25557171
Inflammation, Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	There is mounting evidence that immune cells may trigger various mechanisms that enhance tumor growth and metastasis, but no data on the peritumoral inflammation is available for PeCa.	25557886
Inflammation, Ischemic stroke	Altered Intercellular Communication	Inflammation plays an important role in acute ischemic stroke.	25558553
Inflammation, Ischemic stroke	Altered Intercellular Communication	Relationships between higher levels of inflammation markers, especially serum amyloid A, and the severity of acute ischemic stroke were shown.	25558553
Inflammation, Pulmonary Embolism	Altered Intercellular Communication	Preliminary evidence suggests that inflammation plays a role in the development and prognosis of pulmonary embolism (PE).	25558558
Chronic inflammation, Disease	Altered Intercellular Communication	Profiling phospholipid (PL) FAs and their respective oxylipids could predict which obese individuals are more likely to suffer from diseases associated with chronic inflammation or oxidative stress.	25559239
Hepatitis A, Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	We observed heavy ethanol consumption, 12.0%; viral hepatitis, 26.5%; steatosis without heavy ethanol consumption, 43.4%; inflammation, 45.6%; fibrosis, 26.2% and bridging fibrosis/cirrhosis, 29.4%.	25559280
Inflammation, Prostate carcinoma	Altered Intercellular Communication	A close relationship between aging, inflammation, and prostate cancer is widely accepted.	25560177
Inflammation, Carcinogenesis	Altered Intercellular Communication	NF-kB increases inflammation, carcinogenesis and metastatic potential in the prostate.	25560177
Deficit, Impaired cognition	Altered Intercellular Communication	We suggest that the cognitive impairment due to hormonal deficit in the postmenopausal period could be emphasized by the early structural decline of gray matter in female DS subjects.	25560246
Inflammation	Altered Intercellular Communication	This may be a consequence of inflammation on the fibrous trigones and surrounding annulus.	25560735
Inflammation, Primary malignant neoplasm, Ulcerative Colitis	Altered Intercellular Communication	Clinical factors were independently associated with low 5-MeC levels after adjusting for age and sex, including cancer stages II-IV, presence of UC in situ, and marked inflammation.	25561224
Inflammation, Hepatitis, Liver Cirrhosis	Altered Intercellular Communication	Bone Mineral Density, Bone Turnover, and Systemic Inflammation in Non-cirrhotics with Chronic Hepatitis C. Whether chronic HCV, a disease characterized by systemic inflammation, impacts bone mineral density (BMD) independent of cirrhosis is unknown.	25563723
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	We aimed to evaluate the association between BMD, systemic inflammation, and markers of bone turnover in chronic HCV without cirrhosis.	25563723
Inflammation, Rupture	Altered Intercellular Communication	This leads to adventitial inflammation via IL-6 and results in aortic expansion and rupture.	25563839
Disease Progression, Pancreatic Intraductal Papillary Mucinous Neoplasm	Altered Intercellular Communication	To evaluate the association of tumor-associated neutrophils (TANs) with malignant progression in intraductal papillary mucinous neoplasms (IPMNs) and to study the cyst fluid from these lesions for biomarkers of the inflammation-carcinogenesis association.	25563865
Inflammation	Altered Intercellular Communication	A multiplexed assay was performed to evaluate 87 different cyst fluid proteins, including cyst fluid inflammatory markers (CFIMs), as possible surrogate markers for parenchymal inflammation.	25563865
Inflammation, Anger	Altered Intercellular Communication	Expression of anger and ill health in two cultures: an examination of inflammation and cardiovascular risk.	25564521
Inflammation, Leishmaniasis, Visceral, Rheumatoid Factor, Collagen Diseases	Altered Intercellular Communication	African patients with Leishmania donovani infections have signs of strong systemic inflammation and high levels of circulating immune complexes (IC) and rheumatoid factor (RF), all serologic markers of rheumatic disease.	25565324
Inflammation, Genus: Leishmania	Altered Intercellular Communication	As inflammation in general is associated with citrullination, we sought to investigate ACPA responses in Sudanese Leishmania patients.	25565324
Inflammation, Fibrosis Assessment, Schistosoma mansoni, Intestine Resection	Altered Intercellular Communication	Histological examination of the resected bowel revealed Schistosoma mansoni eggs within the mucosa, submucosa of the ileum, caecum and ascending colon, granulomatous inflammation with foreign body giant cells accompanied by fibrosis and eosinophilic infiltrate into the mucosa.	25566612
Infection caused by Helicobacter pylori	Altered Intercellular Communication	We suggested that IDA/ID associated with H. pylori infection might be mediated by inflammation-driven hepcidin production.	25567795
Inflammation, Acute infectious disease	Altered Intercellular Communication	There is a positive correlation between the parameters of inflammation and glucoregulation in diabetics with acute infection.	25568525
Malaria, Vivax, physiopathological	Altered Intercellular Communication	Parasite biomass-related inflammation, endothelial activation, microvascular dysfunction and disease severity in vivax malaria.	25569250
Inflammation, Malaria, Vivax	Altered Intercellular Communication	Peripheral vivax parasitemia correlated with endothelial activation (angiopoietin-2, von-Willebrand-Factor [VWF], E-selectin), whereas markers of total vivax biomass correlated only with systemic inflammation (IL-6, IL-10).	25569250
Inflammation, Malaria, Vivax, physiopathological	Altered Intercellular Communication	Endothelial activation, associated with circulating parasites, and systemic inflammation may contribute to pathology in vivax malaria, with microvascular dysfunction likely contributing to impaired tissue perfusion.	25569250
Inflammation, Calcinosis, Atherosclerosis	Altered Intercellular Communication	Histological findings in patients with CAS extremely resemble those of atherosclerosis and include accumulation and modification of lipoproteins, inflammation, extracellular matrix remodeling, and calcification.	25569379
Inflammation, Cicatricial ectropion	Altered Intercellular Communication	The delicate local anatomy of the lower eyelid region makes this region particularly susceptible for complications after silicone augmentation including local inflammation, tissue retraction, and consecutive cicatricial ectropion leading to lagophthalmus and ocular surface irritation.	25569426
Inflammation	Altered Intercellular Communication	The CH success rate of carious primary molar DPC justifies further research based on careful initial diagnosis ofpulp inflammation reversibility.	25571680
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Agonists of PPARg inhibit inflammation and reduce generation of cartilage degradation products both in vitro and in vivo, and reduce the development/progression of cartilage lesions in OA animal models.	25572230
Inflammation, Hyperplasia	Altered Intercellular Communication	Periostin plays an important role during epidermal hyperplasia in IMQ-induced skin inflammation, independently of the IL-23-IL-17/IL-22 axis.	25572557
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	High mobility group box 1 (HMGB1) has been proved to be implicated in a variety of cell physiological and pathological behaviors including immune response, inflammation and cancer.	25572734
Inflammation, Atherosclerosis	Altered Intercellular Communication	Cigarette smoking and cardiovascular events: role of inflammation and subclinical atherosclerosis from the MultiEthnic Study of Atherosclerosis.	25573855
Inflammatory Bowel Diseases	Altered Intercellular Communication	These findings propose FSPs as potential novel class of inflammation-associated antigens and this in turn may have implications for screening, diagnosis as well as clinical management of patients suffering from IBD and other inflammatory conditions.	25574094
Inflammatory Bowel Diseases	Altered Intercellular Communication	These findings propose FSPs as potential novel class of inflammation-associated antigens and this in turn may have implications for screening, diagnosis as well as clinical management of patients suffering from IBD and other inflammatory conditions.	25574094
Inflammation, Infection, Tissue injury	Altered Intercellular Communication	Inflammation is a normal host defense reaction to infections and tissue injury.	25574748
Inflammation	Altered Intercellular Communication	The results showed that depending on the period of the disease, the process of inflammation is deregulated in different ways.	25574748
Inflammation, HIV Antibodies	Altered Intercellular Communication	To determine associations between circulating markers of immune activation, immune cell senescence, and inflammation with HIV-associated abnormalities of pulmonary function.	25574956
Inflammation, HIV Antibodies, Lung diseases, HIV Infections	Altered Intercellular Communication	Immune activation, immune senescence, and chronic inflammation are characteristics of chronic HIV infection that have been associated with other HIV-associated comorbidities and may be related to pulmonary disease in this population.	25574956
Colorectal Carcinoma, Neoplasms	Altered Intercellular Communication	Colorectal Cancer, Systemic Inflammation, and Outcome: Staging the Tumor and Staging the Host.	25575264
Inflammation	Altered Intercellular Communication	By modulating the gene expression of immune cells, immunonutrition could make it easier for the organism to adapt to the systemic inflammation and oxidative stress induced by RCT.	25575640
Inflammation, Mediastinal Emphysema	Altered Intercellular Communication	Subsequent abdominal imaging showed inflammation in the right iliac fossa, retroperitoneal air pockets with inflammation, and signs of pneumomediastinum.	25576508
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Histopathological examination of the resected specimen revealed intense inflammation of the caecum and no signs of malignancy.	25576508
Inflammation, Periodontitis, Alveolar Bone Loss	Altered Intercellular Communication	IL-6 plays critical roles in bone resorption and the pathogenesis of periodontitis in both inflammation and alveolar bone loss.	25576892
atherosclerotic	Altered Intercellular Communication	Pre-clinical data suggest the existence of a cardiosplenic axis, wherein activation of hematopoietic tissues (notably in the spleen) results in liberation of proinflammatory leukocytes and accelerated atherosclerotic inflammation.	25577441
Inflammation, Arteritis	Altered Intercellular Communication	Splenic activity increased after ACS and was significantly associated with multiple indices of inflammation: 1) up-regulated gene expression of proinflammatory leukocytes; 2) increased C-reactive protein; and 3) increased arterial wall inflammation (FDG uptake).	25577441
Granuloma, Interstitial inflammation	Altered Intercellular Communication	Bronchoscopy showed ill-defined granulomas and chronic interstitial inflammation.	25577532
Inflammation, Obesity, Abdominal, Liver damage, Antihypertensive Agents	Altered Intercellular Communication	After feature selection was performed, several metabolites and cardiometabolic risk markers, including abdominal obesity and markers of liver damage, inflammation, and oxidative stress were significantly perturbed in Quintile 5 (hypertensives) compared with Quintile 1 (P < .05).	25577962
Inflammation, Polyposis, Gastric	Altered Intercellular Communication	The majority of gastric polyps are asymptomatic, occurring secondary to inflammation.	25578789
Inflammation, Dermatitis, Atopic	Altered Intercellular Communication	Interestingly, omalizumab appeared to induce lymphocyte polarisation toward a type 2 immune response and to be able to quench eosinophil-mediated inflammation, particularly in atopic dermatitis patients.	25578818
Inflammation, Asthma, Impaired lung function	Altered Intercellular Communication	Children and adults with asthma and impaired lung function have been reported to have low-grade systemic inflammation, but it is unknown whether this inflammation starts before symptoms and in particular whether low-grade inflammation is present in asymptomatic neonates with reduced lung function.	25579483
Airway structure	Altered Intercellular Communication	Roxithromycin can reduce airway inflammation and airway thickness of dilated bronchus in patients with NCFB.	25580060
Inflammation, Osage language, Hypoxia, Diabetes Mellitus, Obesity, Hypogonadism	Altered Intercellular Communication	Some are shared with obesity, including hypogonadism, altered adrenergic tone, inflammation, oxidative stress, vitamin D deficiency and diabetes mellitus; others are specific to OSA, such as hypoxia and altered glucocorticoids regulation.	25580607
Pigmented lesions, Abnormal color, Malignant Neoplasms	Altered Intercellular Communication	The main diagnostic categories included benign exophytic lesions (45.3%), white benign lesions (13.5%), potentially malignant lesions/disorders (10.1%), intrabony lesions (9.8%), mucosal discoloration (7.8%), benign pigmented lesions (7.3%), chronic trauma/inflammation (3.9%), and oral malignancy (2.1%).	25580799
Thyroid stimulating hormone measurement	Altered Intercellular Communication	Diagnosis of amiodarone-induced thyroid dysfunction was based on hormonal dosages of TSH, FT4 and FT3, endocrinological examination and thyroid ultrasound.	25581954
Inflammation, Primary malignant neoplasm, hypopharynx	Altered Intercellular Communication	Enhanced contact endoscopy allows for predicting histologic changes of laryngeal and hypopharyngeal lesions from inflammation to cancer on based on fine evaluation of the neoangiogenetic changes of the chorion.	25582112
Inflammation, FBN2 wt Allele, Bacterial Infections	Altered Intercellular Communication	Inflammation induced by bacterial infections might play a role in the pathogenesis of CCA.	25582431
Polymyositis, Dermatomyositis, Rhabdomyositis	Altered Intercellular Communication	Clinical values of FDG PET in polymyositis and dermatomyositis syndromes: imaging of skeletal muscle inflammation.	25582454
Inflammation, Total Clearance Predicted Normalized by Dose, Lymphoproliferative Disorders, Pseudoepitheliomatous hyperplasia	Altered Intercellular Communication	The pathogenetic mechanism of CD30(+) cutaneous lymphoproliferative disorders (CLPD) associated with pseudocarcinomatous hyperplasia (PCH) and granulocytic inflammation surrounding atypical CD30(+) lymphocytes remains unclear.	25582534
Inflammation	Altered Intercellular Communication	Ninety-eight subjects aged 10-24 yr with newly-diagnosed T2DM had general inflammation, anthropometric, laboratory and CIMT data collected, and were divided into three groups based on TG/HDL-C tertiles.	25582650
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Interleukin-32 (IL-32) is a novel cytokine involved in inflammation and cancer development.	25583360
Inflammation, Neoplasm Metastasis, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Unraveling the functional role of OPN isoforms in systemic inflammation is essential to understanding their significance as therapeutic targets in diabetes and obesity, and during metastasis development in PDA.	25583441
Airway structure	Altered Intercellular Communication	Asthma is characterized by chronic airway inflammation that is associated with structural changes termed airway remodeling.	25584916
Inflammation	Altered Intercellular Communication	Recently, cytokines/mediators that augment inflammation have been attracting attention in this field.	25584916
Inflammation	Altered Intercellular Communication	This process may lead to inflammation, destabilization of blood vessels, and trigger remodeling.	25584916
Cessation of life, Inflammation, Atrial Fibrillation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Modeled as a continuous variable, after adjustment for anthropomorphic measures, traditional risk factors, markers of inflammation, and other adipokines, significant associations were noted for HF (HR 1.4, CI 1.0-2.0), hard and all CVD (HR 1.3, 1.1-1.7 and 1.3, 1.1-1.6, respectively), and CHD (HR 1.31, 1.0-1.6), but not for AF or death.	25585029
Inflammation	Altered Intercellular Communication	Systemic inflammation and oxidative stress in hemodialysis patients are associated with down-regulation of Nrf2.	25585822
Inflammation, Cardiac complication, Chronic Kidney Diseases	Altered Intercellular Communication	Oxidative stress and inflammation are common features and the main mediators of progression of chronic kidney disease (CKD) and its cardiovascular complications.	25585822
Inflammation	Altered Intercellular Communication	Acute inflammation is necessary to initiate proper wound healing, while chronic inflammation abrogates wound healing.	25586463
Inflammation	Altered Intercellular Communication	Sustained signalling of TLR9 and TLR7 contributes to chronic inflammation by activating the plasmacytoid dendritic cells.	25586463
Inflammation, Sleep Apnea, Obstructive, Metabolic Syndrome X	Altered Intercellular Communication	Sleepiness, inflammation and oxidative stress markers in middle-aged males with obstructive sleep apnea without metabolic syndrome: a cross-sectional study.	25586501
Inflammation, Osage language	Altered Intercellular Communication	Both conditions, if present in OSA, have been reported to be associated with inflammation and disruption of oxidative stress balance that impair the cardiovascular system.	25586501
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	Inflammation plays an important role in tumor proliferation and survival in cancer patients.	25586599
Inflammation	Altered Intercellular Communication	An accelerated tryptophan breakdown rate is associated with inflammation and immune activation.	25586781
Parkinson Disease, Inflammation, palladium	Altered Intercellular Communication	Inflammatory mediators may reflect a role of systemic inflammation in the neurodegenerative process of Parkinson's disease (PD).	25587378
Diabetic Nephropathy, Inflammation	Altered Intercellular Communication	Recent evidence suggests that chronic subclinical inflammation plays a key role in the pathogenesis and progression of diabetic nephropathy.	25587544
Microalbuminuria, Inflammation, Demographics Domain, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Aim of the present study was to investigate possible correlation between the presence and degree of microalbuminuria and markers of inflammation in patients with type 2 diabetes mellitus (DM).	25587544
Inflammation	Altered Intercellular Communication	Despite the use of HAART to control HIV, systemic immune activation and inflammation persists with the consequence of developing serious non-AIDS events.	25587909
Inflammation, Gastrointestinal dysfunction	Altered Intercellular Communication	Gene expression was correlated with systemic markers of intestinal barrier dysfunction and inflammation and intestinal microbiota composition.	25587909
Arteritis, Dental Plaque, Cerebrovascular accident	Altered Intercellular Communication	Carotid artery plaque inflammation is thought to be an important marker of plaque vulnerability and increased stroke risk.	25588553
Inflammation, Dental Plaque	Altered Intercellular Communication	The level of agreement between (18)F-FDG uptake (mean SUVmax and SUVmax ), and target-to-background ratio, symptoms, plaque echolucency, and histological evidence of inflammation was assessed.	25588553
Inflammation	Altered Intercellular Communication	The amount of (18)F-FDG uptake in plaques and the amount of inflammation on histological assessment were significantly correlated (r = 0521, P = 0003).	25588553
Inflammation	Altered Intercellular Communication	(18)F-FDG uptake on PET/CT correlated with histological assessments of inflammation and was higher in patients with symptomatic compared with asymptomatic carotid artery plaques.	25588553
Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	These results support the use of (18)F-FDG PET/CT in the detection inflammation in carotid atherosclerosis, which may be of help in the detection of vulnerable plaques.	25588553
Inflammation, N-Acetylneuraminic acid storage disease	Altered Intercellular Communication	NSD and granulometry index showed the highest accuracy in identifying a significant plaque inflammation, especially if used together in a two-step algorithm.	25588802
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Conventional oral corticosteroids are effective at reducing inflammation associated with ulcerative colitis (UC); however, systemic adverse effects limit their use.	25588902
Inflammation, Optic Neuritis	Altered Intercellular Communication	Optic neuritis (ON) is an acute episode of inflammation in the visual pathway (VP).	25588974
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Furthermore, protein fragments associated with progression of CKD originated mostly from proteins related to inflammation and tissue repair.	25589610
Inflammation, Impaired cognition, Nerve Degeneration	Altered Intercellular Communication	Whether chronic inflammation plays a causal role in cognitive decline in aging and neurodegeneration has not been established.	25589773
Inflammation, Cognition Disorders	Altered Intercellular Communication	Here we report a mechanistic link between chronic inflammation and aging microglia and a causal role of aging microglia in neurodegenerative cognitive deficits.	25589773
Abscess, Inflammation	Altered Intercellular Communication	One week and 6 weeks after surgery, the presence of suture abscesses and focal inflammation was assessed at the entrance and exit of the sutures.	25590472
Intraocular inflammation	Altered Intercellular Communication	Postmarketing analysis of aflibercept-related sterile intraocular inflammation.	25590968
Low Vision, Intraocular inflammation, Hypopyon, Pain Distress Question	Altered Intercellular Communication	Most cases consisted of initial loss of vision and intraocular inflammation without prominent redness, severe pain, or hypopyon.	25590968
Inflammation, Unspecified visual loss	Altered Intercellular Communication	Although final vision was overall unchanged, some patients developed permanent vision loss, which may have resulted from inflammation and/or progression of the underlying disease.	25590968
Inflammation, Infectious Endophthalmitis	Altered Intercellular Communication	Distinguishing sterile inflammation and infectious endophthalmitis at the time of presentation may often be difficult, and cautious evaluation and management of these patients are warranted.	25590968
Inflammation, Papilledema	Altered Intercellular Communication	Besides a unilateral papillary edema, serological investigations revealed elevated inflammation parameters with a positive (cytoplasmic) anti-neutrophil cytoplasmic autoantibodies (c-ANCA) titer.	25591900
Inflammatory Bowel Diseases, Inflammation, Damage	Altered Intercellular Communication	Plain magnetic resonance imaging as an alternative in evaluating inflammation and bowel damage in inflammatory bowel disease--a prospective comparison with conventional magnetic resonance follow-through.	25592192
Inflammation, Non-Small Cell Lung Carcinoma, Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	Recent evidence demonstrated an enhanced metastasis of non-small cell lung cancer (NSCLC) cells induced by lipopolysaccharide (LPS) stimulation, which reflected an important role of inflammation in tumor progression.	25592377
Hyperglycemia, Inflammation	Altered Intercellular Communication	Increased plasma DPP4 activities predict new-onset hyperglycemia in Chinese over a four-year period: possible associations with inflammation.	25592717
Inflammation, Hyperglycemia	Altered Intercellular Communication	Our objective was to determine whether DPP4 acts as a link between low-grade chronic inflammation and hyperglycemia.	25592717
Inflammation, Chronic Kidney Diseases, Diabetes Mellitus	Altered Intercellular Communication	Inflammation plays an important role in the pathogenesis of chronic kidney disease (CKD) and diabetes mellitus.	25592836
Inflammation, Pterygium Of Conjunctiva And Cornea	Altered Intercellular Communication	Chronic inflammation is a critical process in pterygium development and progression, including promotion of angiogenesis.	25593504
Communicable Diseases, Inflammation	Altered Intercellular Communication	C-reactive protein (CRP) and the erythrocyte sedimentation rate (ESR) are often ordered together in patients with suspected infection or inflammation.	25594234
ARCN1 gene, Inflammation	Altered Intercellular Communication	Collectively, these findings suggest that IL-33 expression levels are increased in COPD and related to airway and systemic inflammation.	25595648
Inflammation, Hypertension, CTCAE, Liver Cirrhosis	Altered Intercellular Communication	Liver cirrhosis is associated with inflammation which is aggravated by portal hypertension.	25595667
Inflammation	Altered Intercellular Communication	Inflammation is believed to play a pivotal role in the etiology of postoperative AF.	25596472
Inflammation, Subarachnoid Hemorrhage, Aneurysmal	Altered Intercellular Communication	Inflammation, negative nitrogen balance, and outcome after aneurysmal subarachnoid hemorrhage.	25596503
ACSM3 gene, Inflammation, Subarachnoid Hemorrhage	Altered Intercellular Communication	To analyze the impact of inflammation and negative nitrogen balance (NBAL) on nutritional status and outcomes after subarachnoid hemorrhage (SAH).	25596503
ACSM3 gene, Inflammation	Altered Intercellular Communication	Negative NBAL after SAH is influenced by inflammation and associated with an increased risk of HAI and poor outcome.	25596503
ACSM3 gene, Inflammation	Altered Intercellular Communication	Underfeeding and systemic inflammation are potential modifiable risk factors for negative NBAL and poor outcome after SAH.	25596503
Deglutition Disorders, Radiation injury, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The most frequent grade 3-4 adverse events were mucosal inflammation (25 [40%] of 62 patients in the chemoradiotherapy group vs 37 [42%] of 89 patients in the radiotherapy plus panitumumab group), dysphagia (20 [32%] vs 36 [40%]), and radiation skin injury (seven [11%] vs 21 [24%]).	25596659
Deglutition Disorders, Radiation injury, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The most frequent grade 3-4 adverse events were dysphagia (17 [27%] of 63 patients in the chemoradiotherapy group vs 35 [40%] of 87 in the panitumumab plus chemoradiotherapy group), mucosal inflammation (15 [24%] vs 48 [55%]), and radiation skin injury (eight [13%] vs 27 [31%]).	25596660
Frontotemporal dementia	Altered Intercellular Communication	This study suggests that glutamate excitotoxicity may play a role in the pathogenesis of bvFTD and that [(11)C]ABP688 may prove a suitable marker of glutamatergic neurotransmission in vivo.	25596865
Inflammation, hepcidin, Anemia	Altered Intercellular Communication	Mass spectrometry evaluation of the hepcidin-25 assay in the differential diagnosis of iron deficiency anaemia with concurrent inflammation and anaemia of inflammation in elderly patients.	25598191
Inflammation, hepcidin, Intradermal Route of Drug Administration	Altered Intercellular Communication	Receiver operating characteristics curve analysis revealed that mass spectrometry analysis of hepcidin-25 does not appear to be superior to ferritin in the diagnosis of ID in elderly anaemic patients with concurrent inflammation.	25598191
Inflammation, Metabolic Diseases	Altered Intercellular Communication	Elevated g-glutamyltransferase (GGT) is an important risk factor for cardiometabolic diseases, which may result from chronic low-grade inflammation.	25598349
Inflammation, Metabolic Diseases	Altered Intercellular Communication	Leukocyte count is widely considered a marker of inflammation and is also an independent predictor of cardiometabolic diseases.	25598349
Inflammation	Altered Intercellular Communication	These findings indicate that serum GGT may be closely related with subclinical low-grade inflammation in children and adolescents.	25598349
ARCN1 gene, Inflammation, Neoplasms	Altered Intercellular Communication	Inflammation might have a key pathogenetic role linking the above tumor markers with the severity of COPD.	25598350
Inflammation, Epilepsy, Trauma, Nervous System	Altered Intercellular Communication	It has been demonstrated that inflammation may contribute to epileptogenesis and cause neuronal injury in epilepsy.	25598431
Inflammation, Hepatic Insufficiency, physiopathological, Hypertension, CTCAE, Liver Cirrhosis	Altered Intercellular Communication	In patients with cirrhosis, serum ferritin levels are associated with markers of liver insufficiency, inflammation, and circulatory dysfunction but not portal hypertension.	25599219
Inflammation, Extracellular Matrix, Autoinflammation, Nasal cartilage loss	Altered Intercellular Communication	Biochemical markers indicative for autoinflammation and immunity (VICM, CRP, and CRPM), synovial inflammation (CIIIM), cartilage loss (CIIM), and bone degradation (CIM) were analyzed.	25599306
Pain Distress Question, Inflammation	Altered Intercellular Communication	DNA collected from saliva was genotyped for a priori selected genes involved with pain modulation (COMT and AVPR1A) and inflammation (IL1B and TNF/LTA).	25599310
Degenerative polyarthritis, Inflammation, Lower extremity pain	Altered Intercellular Communication	Osteoarthritis (OA) of the knee is a progressive disease that is associated with inflammation of the joints and lower extremity pain.	25599456
Inflammation	Altered Intercellular Communication	Oxidative stress resulting from the accumulation of ROS and/or defective removal of ROS by antioxidants has detrimental effects on cellular functions and may contribute to chronic inflammation.	25599773
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Although our data suggest that expression of the gene encoding p22phox is not associated with chronic inflammation in patients with UC, other mechanisms can affect oxidative stress in these patients.	25599773
Inflammation, Fibrosis Assessment, Substance, Hernia, Incisional hernia	Altered Intercellular Communication	Primitive hernia with loss of substance and big incisional hernia repair requires a prosthetic material which not induce, especially in the area of visceral peritoneal contact, chronic inflammation and fibrosis.	25600559
Inflammation, herpesvirus 1, human	Altered Intercellular Communication	Our clinical and microbiological data suggest that severe HSV-1 infection is the driver of periodontal inflammation in this case.	25600604
Refractory anemias, Inflammation	Altered Intercellular Communication	The contribution of patient-reported components to high DAS28 should inform decisions on disease-modifying or pain-management approaches in the treatment of RA when inflammation may be well controlled.	25600850
Liver parenchyma, Inflammation, Fibrosis Assessment, Intrahepatic Large Bile Duct, Hyperplasia	Altered Intercellular Communication	Histologic examination of resection specimens revealed markedly dilated large intrahepatic bile ducts with variable degrees of mural fibrosis, periductal gland hyperplasia, inflammation, and liver parenchymal atrophy.	25600951
Inflammation, Obesity	Altered Intercellular Communication	Long-term consumption of fatty foods is associated with obesity, macrophage activation and inflammation, metabolic imbalance, and a reduced lifespan.	25601202
Myelofibrosis, Bone Marrow	Altered Intercellular Communication	Assessment of bone marrow inflammation in patients with myelofibrosis: an 18F-fluorodeoxyglucose PET/CT study.	25601337
Myelofibrosis, Bone Marrow, Hematopoietic Neoplasms, Extramedullary Hematopoiesis Function	Altered Intercellular Communication	Myelofibrosis is a haematopoietic stem cell neoplasm characterized by bone marrow inflammation, reactive marrow fibrosis and extramedullary haematopoiesis.	25601337
Myelofibrosis, Bone Marrow	Altered Intercellular Communication	(18)F-FDG PET/CT is as a promising technique for the quantitation of bone marrow inflammation in myelofibrosis.	25601337
Atrophic, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Atrophy was confined to the oxyntic mucosa in 10 patients, with intramucosal inflammation in a diffuse or basal-predominant pattern.	25602795
Inflammation, Depressed mood	Altered Intercellular Communication	C-reactive protein (CRP) is a heritable biomarker of systemic inflammation that is commonly elevated in depressed patients.	25603415
Impaired cognition, Pathology	Altered Intercellular Communication	Multivariable analyses adjusted for socio-demographic characteristics, smoking, ischemic pathologies, cognitive impairment and inflammation-related chronic pathologies.	25603415
Inflammation	Altered Intercellular Communication	It is thought that some of these preformed crystals within articular cartilage spill over into the joint space and trigger an acute attack of inflammation.	25603588
Inflammation, Calcifying Fibrous Pseudotumor	Altered Intercellular Communication	Surgical exploration revealed multiples solid nodules of the vaginal wall, with, at frozen section analysis, fibroblastic tissue, vessels and chronic inflammation without malignity, suggestive of fibrous pseudotumor of the tunica vaginalis.	25603639
Peripheral Arterial Diseases	Altered Intercellular Communication	Endothelial Cell Inflammation and Antioxidant Capacity are Associated With Exercise Performance and Microcirculation in Patients With Symptomatic Peripheral Artery Disease.	25603804
Inflammation, Peripheral Arterial Diseases	Altered Intercellular Communication	We determined whether exercise performance and lower extremity microcirculation were associated with endothelial cell inflammation, oxidative stress, and apoptosis and with circulating biomarkers of inflammation and antioxidant capacity in 160 patients with symptomatic peripheral artery disease (PAD).	25603804
Inflammation, Apolipoprotein E	Altered Intercellular Communication	Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration.	25604058
Inflammation	Altered Intercellular Communication	Our results underline the inflammatory role of APOE in sterile inflammation in the immunosuppressive subretinal space.	25604058
methyldopa, Inflammation	Altered Intercellular Communication	They provide rationale for the implication of IL-6 in AMD and open avenues toward therapies inhibiting pathogenic chronic inflammation in late AMD.	25604058
Coinfection, Inflammation, Hepatitis C	Altered Intercellular Communication	Notably, the levels of immune activation and inflammation in patients with previous VL were not related to the time of VL diagnosis, the number of VL relapses, or hepatitis C virus (HCV) coinfection.	25604328
Inflammation, Takayasu Arteritis	Altered Intercellular Communication	Th1 and Th17 cytokines drive inflammation in Takayasu arteritis.	25604824
vascular inflammations	Altered Intercellular Communication	The nature of the T cells driving vascular inflammation and the effects of glucocorticoids on the systemic components of TAK are not understood.	25604824
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Chronic inflammation may be related to breast cancer risk through a mechanism involving the percent of breast area that is dense (percent MD).	25604866
Inflammation, Pulmonary Fibrosis	Altered Intercellular Communication	Hypoxic epithelial necrosis triggers neutrophilic inflammation via IL-1 receptor signaling in cystic fibrosis lung disease.	25607238
Inflammation, Hypoxia, Cystic Fibrosis	Altered Intercellular Communication	Although hypoxia is common in airways from patients with cystic fibrosis (CF), its role in neutrophilic inflammation remains unknown.	25607238
Inflammation, Airway Obstruction, Necrosis	Altered Intercellular Communication	We recently demonstrated that hypoxic epithelial necrosis caused by airway mucus obstruction precedes neutrophilic inflammation in Scnn1b-transgenic (Scnn1b-Tg) mice with CF-like lung disease.	25607238
Airway structure, Obstruction, Lung diseases, Necrosis	Altered Intercellular Communication	To determine the role of epithelial necrosis and IL-1R signaling in the development of neutrophilic airway inflammation, mucus obstruction, and structural lung damage in CF lung disease.	25607238
airway disease, Inflammation, Bacterial Infections	Altered Intercellular Communication	Our results support an important role of hypoxic epithelial necrosis in the pathogenesis of neutrophilic inflammation independent of bacterial infection and suggest IL-1R as a novel target for antiinflammatory therapy in CF and potentially other mucoobstructive airway diseases.	25607238
Inflammation, Periodontitis, Diabetes Mellitus, diabetic	Altered Intercellular Communication	There is scientific data to support the existence of a two-way relationship between diabetes and periodontitis, with diabetes increasing the risk for periodontitis, and periodontal inflammation negatively affecting the diabetic status.	25607396
Peritonitis, Acute appendicitis NOS (disorder), Gastrointestinal Hemorrhage, Diverticulitis, Intestinal Obstruction, Hernia, Inguinal	Altered Intercellular Communication	Of the 29 S MD cases, 14 had intestinal obstruction, seven cases showed lower gastrointestinal bleeding, five cases presented acute inflammation (diverticulitis) and three cases were complicated with peritonitis; 15 cases of AS MD were discovered during surgical interventions for acute appendicitis (14 cases) or inguinal hernia (one case).	25607401
ARCN1 gene, Pulmonary Emphysema, Airway structure	Altered Intercellular Communication	High-resolution computed tomography (HRCT) phenotypes of COPD may reflex the pathological basis of COPD indirectly by evaluating the small airway inflammation and emphysema.	25607515
Dermatitis	Altered Intercellular Communication	Preclinical mouse studies have demonstrated efficacy of abobotulinumtoxinA in improving psoriasiform skin inflammation.	25607710
Inflammation, Biliary calculi	Altered Intercellular Communication	In conjunction with the patient's history of laparoscopic cholecystectomy 1 year prior, the findings were consistent with inflammation around a migrated subdiaphragmatic gallstone.	25608158
Communicable Diseases, Inflammation	Altered Intercellular Communication	A similar pattern is noted for inflammation (N = 3,537, 78%), infection (N = 2,451, 54%) and injury (N = 3,401, 75%).	25608728
Neuralgia	Altered Intercellular Communication	Our investigation revealed a clear shift of T-cell subsets towards anti-inflammation in patients with neuropathic pain.	25608762
malignant disease, Granulomatous inflammation	Altered Intercellular Communication	Our results show that great caution should be exercised when evaluating FDG-avid PET-CT nodes in patients with known malignant disease, as a significant proportion of these lesions may be benign, particularly in geographic locations with a high background prevalence of granulomatous inflammation.	25608976
Hyperlipidemia, Rheumatoid Arthritis, Inflammation, Coronary heart disease	Altered Intercellular Communication	Association of hyperlipidaemia, inflammation and serological status and coronary heart disease among patients with rheumatoid arthritis: data from the National Veterans Health Administration.	25609412
Inflammation, Refractory anemias, Coronary heart disease, Cerebrovascular accident, Rheumatoid Arthritis, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	To examine the association of serum lipids, inflammation and seropositivity on coronary heart disease (CHD) and stroke in patients with rheumatoid arthritis (RA).	25609412
Refractory anemias, Inflammation, Cerebrovascular accident, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	CRP and ESR were similarly associated with increase MI risk and stroke, reflecting the prominent role of inflammation in CHD risk in RA.	25609412
Inflammation, Metabolic Diseases, Obesity	Altered Intercellular Communication	Accurate identification of obesity, systemic inflammation, and atherogenic lipid profile is key to assessing the risk of cardiometabolic diseases.	25609936
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	C-reactive protein (CRP) is a marker of systemic inflammation that has been associated with the incidence and prognosis for a number of different cancers.	25613115
Malignant neoplasm of liver, Inflammation, Hepatobiliary Disorder	Altered Intercellular Communication	Our findings suggest that levels of systemic inflammation may serve as a long-term marker of liver cancer and liver disease.	25613115
Inflammation, Brain Injuries	Altered Intercellular Communication	Levels of LBP, Il-10, IL-6 and CRP, as well as S100B, were measured as markers of inflammation and brain damage by commercially available immunometric tests.	25613713
Inflammation	Altered Intercellular Communication	Our data show that blood levels of inflammation markers may be used as early predictors of stroke-associated infection.	25613713
Inflammation, Primary malignant neoplasm, Malnutrition, Fatigue	Altered Intercellular Communication	Is glutamine deficiency the link between inflammation, malnutrition, and fatigue in cancer patients?	25614125
Inflammation, Primary malignant neoplasm, Neoplasms, Fatigue	Altered Intercellular Communication	Evaluation of potential associations between plasma glutamine levels and the incidence of cancer related fatigue, physical performance, poor nutritional status, and inflammation in patients with solid tumors.	25614125
Inflammation, Primary malignant neoplasm, Malnutrition, Fatigue	Altered Intercellular Communication	The data support our working hypothesis that in cancer patients systemic inflammation maintains a catabolic situation leading to malnutrition symptoms and glutamine deprivation, the latter being associated with cancer related fatigue.	25614125
Airway structure	Altered Intercellular Communication	Ceramide-1-phosphate inhibits cigarette smoke-induced airway inflammation.	25614161
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	We aimed to clarify the role of C1P in the pathogenesis of CS-triggered pulmonary inflammation and emphysema in humans and mice.	25614161
Pulmonary Emphysema, Acute and chronic inflammation	Altered Intercellular Communication	C1P reduced CS-induced acute and chronic lung inflammation and development of emphysema in mice, which was associated with a reduction in nSMase and NF-kB activity in the lungs.	25614161
Pneumonitis	Altered Intercellular Communication	Our results suggest that C1P is a potential target for anti-inflammatory treatment in CS-induced lung inflammation.	25614161
Granulomatous inflammation	Altered Intercellular Communication	Pathologist awareness of this rare cause of granulomatous inflammation aids recognition of BCG-osis and facilitates prompt initiation of antimycobacterial therapy.	25614462
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation, endothelial activation and oxidative stress have been established as key events in the initiation and progression of atherosclerosis.	25614985
Inflammation, Atherosclerosis, Coronary heart disease	Altered Intercellular Communication	High-density lipoprotein cholesterol (HDL-c) is protective against atherosclerosis and coronary heart disease, but its association with inflammation, endothelial activation and oxidative stress is not well established.	25614985
Inflammation	Altered Intercellular Communication	Subjects with low HDL-c had greater concentrations of inflammation, endothelial activation and oxidative stress biomarkers compared to controls.	25614985
Inflammation, Atherosclerosis	Altered Intercellular Communication	It is also an independent predictor for enhanced inflammation and endothelial activation, which are pivotal in the pathogenesis of atherosclerosis and atherosclerosis-related complications.	25614985
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	No association between vitamin D levels and inflammation markers in patients with acute coronary syndrome.	25615956
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	This study demonstrates that calcidiol levels are not associated with the inflammation markers in patients with acute phase ACS.	25615956
Inflammation, Observation Method - Coagulation, Atherosclerosis	Altered Intercellular Communication	Markers of inflammation and coagulation after long-term exposure to coarse particulate matter: a cross-sectional analysis from the multi-ethnic study of atherosclerosis.	25616153
Inflammation, Observation Method - Coagulation, Atherosclerosis	Altered Intercellular Communication	Here we examine long-term associations with inflammation and coagulation in the Multi-Ethnic Study of Atherosclerosis.	25616153
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Our cross-sectional analysis provided some evidence that long-term PM10-2.5 exposure was associated with inflammation and coagulation, but associations were modest and depended on particle composition.	25616153
Inflammation	Altered Intercellular Communication	Specialized proresolving mediators (SPMs) induce resolution of inflammation.	25616438
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) is associated with brain inflammation and reduced levels of SPMs.	25616438
Inflammation, Osteoporosis, Atherosclerosis	Altered Intercellular Communication	Elevated plasma DMG levels are associated with atherosclerotic cardiovascular disease and inflammation, which in turn are related to osteoporosis.	25616506
Arterial Stiffness, Inflammation, Carotid Intima-Media Thickness, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis was evaluated by assessing carotid intima-media thickness by ultrasound, arterial stiffness by Young's modulus and inflammation by C-reactive protein.	25616705
Arterial Stiffness, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Serum levels of methylglyoxal-derived hydroimidazolone-1 in diabetes patients are increased and associated with low-grade inflammation, but not yet arterial stiffness or wall thickness.	25616705
Airway structure	Altered Intercellular Communication	Vitamin D reduces eosinophilic airway inflammation in nonatopic asthma.	25617224
Airway structure	Altered Intercellular Communication	Vitamin D supplementation reduced eosinophilic airway inflammation in patients with nonatopic asthma with severe eosinophilic airway inflammation, but did not affect sputum neutrophils.	25617224
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The neutrophil-to-lymphocyte ratio (NLR), an easily determinable marker of systemic inflammation, has been associated with clinical outcome in various cancer entities.	25617235
Inflammation	Altered Intercellular Communication	Adjuvant treatment with crude rhubarb for patients with systemic inflammation reaction syndrome/sepsis: a meta-analysis of randomized controlled trials.	25617260
Inflammation, Obesity	Altered Intercellular Communication	In addition to its important role as marker of iron stores, serum ferritin is a marker of systemic inflammation, and obesity has been associated with chronic inflammation.	25617548
Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	The diagnosis can be easily mistaken for other neurodegenerative diseases, which are often accompanied by inflammation and the production of cytokines.	25617881
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Wholegrain (WG) consumption is associated with reduced risk of cardiovascular disease, but clinical data on inflammation and immune function is either conflicting or limited.	25618418
Inflammation, Neoplasms	Altered Intercellular Communication	C-reactive protein (CRP) is a sensitive marker of inflammation that has been linked with prognosis in various solid tumours.	25618827
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	The impact of inflammation suppressor pathways on Alzheimer's disease (AD) evolution remains poorly understood.	25619654
Neoplasms, Lymphoma, Conjunctivitis	Altered Intercellular Communication	In three patients a conjunctival tumor of unknown origin, in one case each a papillomatous alteration of the conjunctiva, a conjunctival granulomatous inflammation, and a lymphoma were assumed respectively.	25619666
Inflammation, Electrocardiogram: myocardial infarction (finding), Venous Stroke, Corneal Endothelial Cell Loss	Altered Intercellular Communication	The aim of our study was to characterize and compare the short- and long-term mobilization of endothelial progenitor cells and circulating endothelial cells after acute myocardial infarction or atherothrombotic stroke, and to determine the relationship between these cell counts and plasma concentrations of vascular cell adhesion molecule (VCAM-1) and Von Willebrand factor (VWF) as surrogate markers of endothelial damage and inflammation.	25619946
Inflammation, Neoplasms, Malignant Neoplasms	Altered Intercellular Communication	Pentraxin-3 (PTX3), a modulator of tumor-associated inflammation, is known to be positively correlated with tumor grade and severity of malignancies, but the function and molecular underlying mechanisms of PTX3 remain unclear.	25620175
Communicable Diseases, Inflammation	Altered Intercellular Communication	Both features were attributed to a chronic inflammation because of an abscess in the right iliopsoas caused by infection due to bilateral hip replacement which underwent revision surgery.	25621695
Inflammation, Necrosis	Altered Intercellular Communication	Pathomorphological examination of the testicular tissue revealed focal necrosis and diffuse suppurative inflammation of the testicular tunic.	25623185
Cessation of life, Communicable Diseases, Inflammation, Bacterial Infections	Altered Intercellular Communication	In noninfectious causes of death with decomposition, postmortem investigations failed to reveal results consistent with generalized inflammation or bacterial infections at the time of death.	25623190
Inflammation, Demographics Domain, Cardiovascular Diseases	Altered Intercellular Communication	POD has been associated with systemic inflammation, a known risk factor for cardiovascular and bone disease, both of which are more common in patients with DM.	25623292
Inflammation, Complication Aspects	Altered Intercellular Communication	However, there is mixed evidence that treatment of POD reduces inflammation, improves DM control, and reduces DM complications.	25623292
Inflammation	Altered Intercellular Communication	Clinical evaluation and assessment of synovial inflammation by contrast-enhanced ultrasound (CEUS).	25623520
Inflammation, Arthritis, Psoriatic	Altered Intercellular Communication	Despite the efficacy of TNF inhibitors, most patients with psoriatic arthritis maintain a residual synovial inflammation.	25623520
Inflammation	Altered Intercellular Communication	The secondary outcome was to assess synovial inflammation in hand joints detected by contrast-enhanced ultrasound.	25623520
Inflammation	Altered Intercellular Communication	Synovial inflammation detected by contrast-enhanced ultrasound, analysed by a software system, was also assessed.	25623520
Inflammation, Hemophilic arthropathy, Congenital Abnormality	Altered Intercellular Communication	Point-of-care musculoskeletal ultrasound is critical for the diagnosis of hemarthroses, inflammation and soft tissue abnormalities in adult patients with painful haemophilic arthropathy.	25623830
Inflammation, Hemophilia A, Congenital Abnormality	Altered Intercellular Communication	Using high resolution MSKUS, employing grey scale and power Doppler, we sought to retrospectively (i) investigate soft tissue abnormalities in painful haemophilic joints and (ii) to determine to what extent MSKUS findings, functional or radiographic joint scores correlate with biomarkers of inflammation in PWH.	25623830
Tendinitis, Inflammation, Synovitis, Bursitis, Enthesitis	Altered Intercellular Communication	The most prominent findings (66.5%) pertained to inflammatory soft tissue changes including synovitis, tendinitis, enthesitis, bursitis and fat pad inflammation.	25623830
Data types - Address	Altered Intercellular Communication	The human butyrylcholinesterase (BChE) is an enzyme that has specific roles in cholinergic neurotransmission and it has been associated with AD.	25624079
Asthma, Sinusitis, Chronic sinusitis	Altered Intercellular Communication	Sinus and adenoid inflammation in children with chronic rhinosinusitis and asthma.	25624129
airway disease, Paranasal Sinus Disorder, Airway structure, Asthma, asthma chronic	Altered Intercellular Communication	This observation is consistent with the hypothesis that asthma in these patients is caused or exacerbated by severe upper airway disease and supports the concept that treating sinus disease is paramount in the management of chronic asthma in children using, for the first time, direct measurements of airway inflammation in children.	25624129
Inflammation, Asthma	Altered Intercellular Communication	Leukotriene B4 (LTB4) is an important disease marker, but its role in inflammation of the small airways in asthma has not been established yet.	25624130
IL13 gene	Altered Intercellular Communication	Allergic rhinitis (AR) is an inflammatory condition of the nasal mucosa characterized by symptoms of nasal discharge, itching, sneezing, and congestion.	25624132
Inflammation	Altered Intercellular Communication	Although rectal inflammation was detected, no polyps were found in the rectum.	25624746
Inflammation, Coronary Artery Disease, Atherosclerosis	Altered Intercellular Communication	Abnormal blood rheology and chronic low grade inflammation: possible risk factors for accelerated atherosclerosis and coronary artery disease in Lewis negative subjects.	25626016
Inflammation, Precocious atherosclerosis	Altered Intercellular Communication	To test the hypothesis that abnormal hemorheology and chronic low-grade inflammation are more prevalent in Lewis negative individuals, possibly contributing to premature atherosclerosis.	25626016
Inflammation, Leukocytes	Altered Intercellular Communication	However, markers of inflammation (WBC, hs-CRP, ESR) were significantly elevated and rheological parameters (RBC aggregation, plasma viscosity) were abnormal in Lewis negative subjects, especially when compared to the Le(a-b+) group.	25626016
Autoimmune Diseases, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Aberrant RIG-I signaling leads to inflammation, autoimmune diseases and cancer.	25626059
Inflammation, Pathology, Edema	Altered Intercellular Communication	Ultrasound is useful for non-invasive visualization of focal nerve pathologies probably resulting from demyelination, remyelination, edema or inflammation.	25626722
Inflammation	Altered Intercellular Communication	Surgery induces inflammation and pro-inflammatory cytokines are associated with post-operative complications.	25626738
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Rho kinase (ROCK) is associated with VEGF-driven angiogenesis, as well as with inflammation and fibrosis.	25626969
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Outcome was assessed by analysis of inflammation (CD45), angiogenesis (FITC-dextran), vessel leakage (Texas Red-conjugated Dextran and FITC-labeled lectin) and fibrosis (Sirius Red/Collagen I).	25626969
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	05), whereas DC101 had no effect on inflammation nor on fibrosis.	25626969
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The results suggest that targeting ROCK with AMA0428 not only reduces neoangiogenesis, but also blocks inflammation and fibrosis (contrary to VEGF suppression).	25626969
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Gene and protein expressions related to fibrosis, inflammation, and chondrogenesis were analyzed by quantitative reverse transcription-polymerase chain reaction and immunohistochemistry.	25627290
Inflammation	Altered Intercellular Communication	Symptoms caused by this pathogen are accompanied by intense local and systemic inflammation.	25627751
Airway structure, Nose symptoms	Altered Intercellular Communication	Mucociliary clearance, airway inflammation and nasal symptoms in urban motorcyclists.	25628001
Airway structure	Altered Intercellular Communication	There is evidence that outdoor workers exposed to high levels of air pollution exhibit airway inflammation and increased airway symptoms.	25628001
Inflammation, Traumatic injury	Altered Intercellular Communication	We suggest that these findings may be used to develop new therapeutics to treat the devastating inflammation and cell destruction evoked by CNS injuries.	25628216
Inflammation, Granulation finding	Altered Intercellular Communication	Histological and immunohistochemical examinations of the resected and infarcted neonatal hearts revealed inflammation and granulation tissue formation.	25628406
Inflammation, Postoperative Period	Altered Intercellular Communication	Changes in the Concentrations of Mediators of Inflammation and Oxidative Stress in Exhaled Breath Condensate During Liver Transplantation and Their Relations With Postoperative ARDS.	25628453
eosinophil	Altered Intercellular Communication	Wogonin induces eosinophil apoptosis and attenuates allergic airway inflammation.	25629436
eosinophil, allergic inflammation	Altered Intercellular Communication	To investigate the ability of the flavone wogonin to induce eosinophil apoptosis in vitro and attenuate eosinophil-dominant allergic inflammation in vivo in mice.	25629436
Pneumonitis	Altered Intercellular Communication	Allergic lung inflammation was modeled in mice sensitized and challenged with ovalbumin.	25629436
eosinophil, Respiratory Hypersensitivity	Altered Intercellular Communication	Wogonin administration attenuated allergic airway inflammation in vivo with reductions in BAL and interstitial eosinophil numbers, increased eosinophil apoptosis, reduced airway mucus production, and attenuated airway hyperresponsiveness.	25629436
eosinophil, allergic inflammation	Altered Intercellular Communication	Wogonin induces eosinophil apoptosis and attenuates allergic airway inflammation, suggesting that it has therapeutic potential for the treatment of allergic inflammation in humans.	25629436
Communicable Diseases, Inflammation	Altered Intercellular Communication	However, fracture-related inflammation can make investigations used in the diagnosis of infection less reliable.	25631172
Inflammation, One Vessel Coronary Disease	Altered Intercellular Communication	We investigated the association between circulating biomarkers of inflammation and MRI markers of small vessel disease.	25632086
Inflammation, Cerebral Infarction, Hemorrhagic, Tumor necrosis, Cerebral Small Vessel Diseases, Cerebral microbleeds, vascular inflammations	Altered Intercellular Communication	We performed a cross-sectional study relating a panel of 15 biomarkers, representing systemic inflammation (high-sensitivity C-reactive protein, interleukin-6, monocyte chemotactic protein-1, tumor necrosis factor a, tumor necrosis factor receptor 2, osteoprotegerin, and fibrinogen), vascular inflammation (intercellular adhesion molecule 1, CD40 ligand, P-selectin, lipoprotein-associated phospholipase A2 mass and activity, total homocysteine, and vascular endothelial growth factor), and oxidative stress (myeloperoxidase) to ischemic (white matter hyperintensities/silent cerebral infarcts) and hemorrhagic (cerebral microbleeds) markers of cerebral small vessel disease (CSVD) on MRI in 1,763 stroke-free Framingham offspring (mean age 60.2 +- 9.1 years, 53.7% women).	25632086
Inflammation, Hemorrhagic	Altered Intercellular Communication	Our study supports a possible role for inflammation in the pathogenesis of CSVD, but suggests that differing inflammatory pathways may underlie ischemic and hemorrhagic subtypes.	25632086
Airway structure, Cystic Fibrosis	Altered Intercellular Communication	Patients with cystic fibrosis (CF) lung disease have chronic airway inflammation driven by disrupted balance of T-cell (Th17 and Th2) responses.	25632992
Inflammation, Infectious Lung Disorder	Altered Intercellular Communication	Modulation of Tregs represents a novel strategy to rebalance T-cell responses, dampen inflammation, and ultimately improve outcomes for patients with infective CF lung disease.	25632992
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Higher MMP-8 in MetS is possibly mediated through mechanisms both dependent and independent of chronic low grade inflammation.	25633268
Dental Plaque, CEL gene	Altered Intercellular Communication	The fibroblast activation protein alpha (FAP) was recently proposed as inflammation-induced protease involved in the process of plaque vulnerability.	25633335
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Chronic Kidney Diseases	Altered Intercellular Communication	Effect of paricalcitol on endothelial function and inflammation in type 2 diabetes and chronic kidney disease.	25633573
Inflammation	Altered Intercellular Communication	Vitamin D and its analogs may play a role in regulation of endothelial function and inflammation.	25633573
Alzheimers Disease", Neurotoxicity Syndromes, Data types - Address	Altered Intercellular Communication	This excitatory neurotransmitter is thought to contribute to neurotoxicity in neurodegenerative conditions such as Alzheimer's disease (AD) but the expression of hBCAT in this disease has not previously been investigated.	25633671
Pneumonitis	Altered Intercellular Communication	Microinhalation of gastric secretions might induce lung inflammation leading to OP and relapse.	25633753
Gastrointestinal inflammation	Altered Intercellular Communication	The development of MC is often associated with intestinal inflammation and/or microsatellite instability (MSI).	25634199
Gastrointestinal inflammation	Altered Intercellular Communication	Intestinal inflammation due to IS occurs by the destruction of colonic microvilli and induces chronic diarrhea.	25634199
Gastrointestinal inflammation	Altered Intercellular Communication	It seemed that the cause of MC development was not MSI but intestinal inflammation.	25634199
Gastrointestinal inflammation, Neoplasms	Altered Intercellular Communication	This report provides evidence for an association between neoplasm and IS-induced intestinal inflammation.	25634199
Granulomatous inflammation	Altered Intercellular Communication	From 83 fine-needle aspiration (FNA) specimens, 54.8% (40/73) showed granulomatous inflammation, 62.5% (40/64) had positive mycobacterial culture, and 73.3% (11/15) tested positive with Xpert MTB/RIF (Cepheid, Sunnyvale, CA).	25634205
Granulomatous inflammation	Altered Intercellular Communication	From 62 biopsy samples, 96.8% (60/62) showed granulomatous inflammation, 64.6% (31/48) had positive mycobacterial culture, and 46.1% (6/13) tested positive with Xpert MTB/RIF.	25634205
Conjunctivitis, Allergic Conjunctivitis	Altered Intercellular Communication	Clinical characteristics associated with conjunctival inflammation in allergic rhinoconjunctivitis.	25634218
Conjunctivitis, Radiation Arc	Altered Intercellular Communication	The cytological characteristics of conjunctival inflammation in patients with ARC were assessed and then correlated to clinical characteristics.	25634218
Inflammation, Nasal inflammation	Altered Intercellular Communication	Patients were subdivided into 3 groups on the basis of cytological phenotype: (1) nasal and conjunctival inflammation, (2) nasal inflammation only, and (3) no mucosal inflammation.	25634218
Conjunctivitis	Altered Intercellular Communication	Male sex (odds ratio, 8.4; P = .005) and eye itching (odds ratio, 1.3; P = .019) significantly correlated with conjunctival inflammation.	25634218
Conjunctivitis	Altered Intercellular Communication	The odds of exhibiting conjunctival inflammation, at multivariate analysis, increased 13-fold for men and 1.5-fold for each point on the eye itching scale.	25634218
Conjunctivitis	Altered Intercellular Communication	A cutoff value of 3 or more for eye itching effectively identified patients with conjunctival inflammation.	25634218
Radiation Arc, Conjunctivitis	Altered Intercellular Communication	Our study demonstrates that some clinical manifestations of ARC correlate well with conjunctival inflammation.	25634218
Inflammation, Parkinsonian Disorders	Altered Intercellular Communication	Inflammation mediated by inducible nitric oxide synthase may possibly contribute to the association between welding fume and parkinsonism, but requires verification in a longitudinal study.	25634431
Inflammation, Hemorrhage	Altered Intercellular Communication	The incidence of delayed complications was 1.6 per 1000 procedures (95% confidence interval, 0.3-3.0), which comprised five post-polypectomy bleeds and one post-polypectomy inflammation.	25634931
Inflammation	Altered Intercellular Communication	C1q/TNF-related protein 1 (CTRP-1), a novel adipocyte factor, may participate in the mechanisms of metabolism and inflammation.	25635749
Inflammation, Choline Dehydrogenase, Mitochondrial, Atherosclerosis	Altered Intercellular Communication	The variation of plasma CTRP-1 and IL-6 concentrations may play an important role in reflecting the degree of inflammation in CHD and the severity of coronary arterial atherosclerosis.	25635749
Inflammation, Pancreatic Ductal Adenocarcinoma, Diabetes Mellitus	Altered Intercellular Communication	Analysis of global gene expression profiles suggests a role of acute inflammation in type 3C diabetes mellitus caused by pancreatic ductal adenocarcinoma.	25636208
Inflammation, Fibrosis Assessment, Chronic liver disease, Lymphoproliferative Disorder of the Skin	Altered Intercellular Communication	Angiogenesis and inflammation have been involved in the progression of fibrosis in patients with chronic liver disease (CLD).	25636502
Pain Distress Question, Inflammation, Neuralgia	Altered Intercellular Communication	MicroRNAs are found to be involved in the generation and maintenance of pain in animal models of inflammation and neuropathic pain.	25636687
Refractory anemias, Inflammation, Disease	Altered Intercellular Communication	Our findings show substantial detrimental role of exposure to RA flare and cumulative burden of RA disease severity in CVD risk in RA, suggesting important cardiovascular benefits associated with tight inflammation control and improved flare management in patients with RA.	25637001
Inflammatory abnormality of the eye	Altered Intercellular Communication	Mean BCVA at the onset of ocular inflammation was 0.253 +- 0.424.	25637181
Inflammatory abnormality of the eye	Altered Intercellular Communication	Mean BCVA after treatment was 0.036 +- 0.242, significantly better than at the onset of ocular inflammation (P < .05).	25637181
Syphilitic, Inflammatory abnormality of the eye	Altered Intercellular Communication	Retrospective, descriptive and non-comparative study of a series of patients hospitalized between 2007 and 2013 in our department of ophthalmology for management of ocular inflammation associated with a positive syphilitic serology.	25637233
Inflammatory abnormality of the eye	Altered Intercellular Communication	Every structure of the eye may be involved with syphilis; therefore, syphilis must be systematically sought during the etiologic assessment of ocular inflammation even in the absence of historical risk factors.	25637233
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The association between reduction in inflammation and changes in lipoprotein levels and HDL cholesterol efflux capacity in rheumatoid arthritis.	25637346
Inflammation	Altered Intercellular Communication	Patients with bacterial LRTI showed significant overexpression of inflammation and neutrophil genes (bacterial > bacterial-viral > viral), and those with viral LRTI displayed significantly greater overexpression of interferon genes (viral > bacterial-viral > bacterial).	25637350
Inflammation	Altered Intercellular Communication	In comparison with both control and HTN(-)HFpEF, patients with HTN(+)HFpEF had increased left ventricular end-diastolic pressure, left atrial volume, N-terminal propeptide of brain natriuretic peptide, total, collagen-dependent, and titin-dependent stiffness, insoluble collagen, increased titin phosphorylation on PEVK S11878(S26), reduced phosphorylation on N2B S4185(S469), and increased biomarkers of inflammation.	25637629
Inflammation	Altered Intercellular Communication	Aging is associated with an increase in a chronic, low-grade inflammation.	25638154
Inflammation, Chronic disease, Heavy Chain Disease	Altered Intercellular Communication	Our findings also suggest a possibility that systemic inflammation associated with chronic diseases may explain accelerated aging phenomenon previously observed among the patients with heavy disease burden.	25638154
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Lactosylceramide-accumulation in lipid-rafts mediate aberrant-autophagy, inflammation and apoptosis in cigarette smoke induced emphysema.	25638276
Inflammation, Nasal sinus, Odontogenic Cysts	Altered Intercellular Communication	The most common cause of unilateral paranasal sinusitis was odontogenic infection, as seen in 138 cases (72.6%), followed by chronic inflammation in 43 cases (22.6%).	25638394
Sepsis, Inflammation	Altered Intercellular Communication	IL-17 was helpful for inflammation in severe sepsis.	25638510
Sarcoidosis	Altered Intercellular Communication	Rarely, it can be caused by systemic inflammatory conditions such as sarcoidosis.	25638512
Inflammation, Vitreous opacities	Altered Intercellular Communication	On presentation, diffuse keratic precipitates, anterior chamber inflammation and snowball-like vitreous opacity were observed.	25639036
Inflammation, Arthrodermataceae, Bryozoa	Altered Intercellular Communication	Anthropophilic dermatophytes resulted in a score of 1.82 points for the severity of inflammation and a score of 1.84 points for the extent of lesions while zoophilic dermatophytes resulted in a score of 2.14 points for the severity of inflammation and a score of 1.50 points for the extent of lesions.	25639303
Inflammation, Chronic sinusitis	Altered Intercellular Communication	Level of secreted HMGB1 correlates with severity of inflammation in chronic rhinosinusitis.	25639490
Inflammation, Chronic sinusitis	Altered Intercellular Communication	The purpose of this study was to determine the relationship between the HMGB1 level in nasal secretions and the severity of inflammation in chronic rhinosinusitis.	25639490
Inflammation, Chronic sinusitis	Altered Intercellular Communication	Our results showed that HMGB1 is secreted into the extracellular area space in the upper airway, and HMGB1 levels in nasal lavage fluid correlate with severity of inflammation, as assessed by the Lund-Mackay staging system for chronic rhinosinusitis.	25639490
Inflammation	Altered Intercellular Communication	Inflammation can cause endoplasmic reticulum (ER) stress and therefore activates the unfolded protein response (UPR).	25640174
Inflammation	Altered Intercellular Communication	These findings suggest that MANF may be a negative regulator of inflammation and mediate the crosstalk between the NF-kB pathway and ER stress.	25640174
Inflammation	Altered Intercellular Communication	Further experiments reveal the possible mechanisms for the anti-calcification of PC crosslinking including (1) inhibiting inflammation cell attachment, and secretion of inflammatory factors such as MMPs and TNF-a, (2) preventing elastin degradation by elastase, and (3) direct inhibition of mineral nucleation in elastin.	25641644
Inflammation, Pancreatic Ductal Adenocarcinoma	Altered Intercellular Communication	Cancer-associated inflammation is a key molecular feature of pancreatic ductal adenocarcinoma.	25641673
Celiac Disease, Malabsorption Syndrome, Gastrointestinal inflammation	Altered Intercellular Communication	Celiac disease, characterized by intestinal inflammation and malabsorption, occurs in 1 per cent of the population and is often undiagnosed.	25642877
Inflammation	Altered Intercellular Communication	Bonar scores and synovial inflammation grade were checked 5 weeks after the injection.	25643855
prostatitis	Altered Intercellular Communication	Smoking Is Associated with Acute and Chronic Prostatic Inflammation: Results from the REDUCE Study.	25644151
prostatitis	Altered Intercellular Communication	As prostate inflammation is common, we hypothesized smoking could contribute to prostate inflammation.	25644151
prostatitis	Altered Intercellular Communication	Prostate inflammation was assessed by systematic central review blinded to smoking status.	25644151
Chronic inflammation	Altered Intercellular Communication	In contrast, current smoking was linked with chronic inflammation in the baseline biopsy, but not at 2- and 4-year biopsies.	25644151
prostatitis	Altered Intercellular Communication	Acute and chronic prostate inflammations were identified in 1,261 (15%) and 6,352 (78%) baseline biopsies, respectively.	25644151
prostatitis	Altered Intercellular Communication	In conclusion, among men undergoing prostate biopsy, current smoking was independently associated with acute and possibly chronic prostate inflammations.	25644151
Inflammatory abnormality of the eye	Altered Intercellular Communication	The main outcome measures were control of ocular inflammation, progression of disease, and surgical success.	25644537
Inflammatory abnormality of the eye	Altered Intercellular Communication	Control of ocular inflammation before lid surgery was achieved in all cases.	25644537
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Dysbiosis gut microbiota associated with inflammation and impaired mucosal immune function in intestine of humans with non-alcoholic fatty liver disease.	25644696
Inflammation, Non-alcoholic Fatty Liver Disease, Impaired health, Dysbiosis	Altered Intercellular Communication	We postulate that aside from dysbiosis of the gut microbiota, gut microbiota-mediated inflammation of the intestinal mucosa and the related impairment in mucosal immune function play an important role in the pathogenesis of NAFLD.	25644696
Airway structure, Hypoxia, Osage language	Altered Intercellular Communication	Increased alveolar NO concentration was related to the severity of nocturnal oxygen desaturation in patients with OSA, linking the distal airway inflammation to intermittent hypoxia.	25645200
Inflammation, Atherosclerosis	Altered Intercellular Communication	Purinergic signaling plays an important role in inflammation and vascular integrity, but little is known about purinergic mechanisms during the pathogenesis of atherosclerosis in humans.	25645301
Inflammation, Demographics Domain, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Previous studies reported beneficial effects of cocoa or chocolate on insulin resistance, oxidative stress, and inflammation, which are important risk factors of type 2 diabetes mellitus (DM).	25646334
Granulomatous inflammation, Malignant Neoplasms	Altered Intercellular Communication	Differentiation between granulomatous inflammation and malignancy is challenging with 18F-FDG-PET/CT because of a large number of false-positive findings.	25646704
Gastrointestinal inflammation, Dysbiosis	Altered Intercellular Communication	Fecal microbial transplant (FMT) is a potential therapeutic option for individuals with CD based on the hypothesis that changing the fecal dysbiosis could promote less intestinal inflammation.	25647155
Inflammation, ovarian neoplasm	Altered Intercellular Communication	We prospectively examined the association between HPA activity, tumor-associated inflammation, and survival in ovarian cancer patients prior to treatment.	25647344
Inflammation, Congenital Abnormality	Altered Intercellular Communication	HPA abnormalities may reflect poor endogenous control of inflammation, dysregulation caused by tumor-associated inflammation, broad circadian disruption, or some combination of these factors.	25647344
Inflammation, Inflammatory disorder, HIV Infections	Altered Intercellular Communication	Chronic inflammation and immune activation occur in both HIV infection and normal aging and are associated with inflammatory disease.	25647525
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Inflammation, and more generally, the immune response are thought to influence the development of prostate cancer.	25648070
Inflammation, Cardio-Renal Syndrome, Craniosynostosis, Atherosclerosis	Altered Intercellular Communication	To determine levels of interleukin-8 (IL-8) and plasminogen activator inhibitor-1 (PAI-1) in different cardiorenal syndrome (CRS) modalities and to compare findings to some already investigated direct and indirect parameters of inflammation and atherosclerosis.	25648331
hepcidin, Nephritis	Altered Intercellular Communication	Urinary monocyte chemoattractant protein-1 (MCP-1) and hepcidin are potential biomarkers of renal inflammation.	25648911
Inflammation, Hyperuricemia	Altered Intercellular Communication	Hyperuricaemia causes a shift in the IL-1b/IL-1Ra balance produced by PBMCs after exposure to MSU crystals and TLR-mediated stimuli, and this phenomenon is likely to reinforce the enhanced state of chronic inflammation.	25649144
Granulomatous inflammation, Malignant Neoplasms, Actinomycosis	Altered Intercellular Communication	Histological study showed a polymorphous granulomatous inflammation without signs of malignancy with actinomycotic grains.	25649200
Multimorbidity	Altered Intercellular Communication	Inflammation Partially Mediates the Association of Multimorbidity and Functional Limitations in a National Sample of Middle-Aged and Older Adults: The MIDUS Study.	25649677
Multimorbidity, Inflammation	Altered Intercellular Communication	Here we examine the role of inflammation in mediating the relationship between multimorbidity and disability.	25649677
Multimorbidity, Inflammation	Altered Intercellular Communication	After adjustment for potential confounds, multimorbidity was positively associated with inflammation (p < .001) and functional limitations (p < .001), and inflammation partially mediated the link between multimorbidity and functional limitations (p < .01).	25649677
Disability, Inflammation	Altered Intercellular Communication	Inflammation may be an important biological mechanism through which chronic medical conditions are linked to disability in later life.	25649677
Inflammation, Common Compensatory Fascial Pattern	Altered Intercellular Communication	The rheumatologist findings had 94.2% sensitivity and 84.6% specificity for inflammation; corresponding values were 80.7% and 100% for MSU microcrystals and 66.7% and 93.2% for CCP microcrystals.	25649725
Crohn Disease, Inflammation	Altered Intercellular Communication	Crohn's disease of the small bowel: evaluation of ileal inflammation by diffusion-weighted MR imaging and correlation with the Harvey-Bradshaw index.	25650083
Inflammation, Crohn Disease	Altered Intercellular Communication	This study was undertaken to determine the diagnostic capabilities of diffusion-weighted magnetic resonance imaging (DWI) in detecting ileal inflammation in Crohn's disease (CD), and to verify the correlation between the DWI sequences and the Harvey-Bradshaw index (HBI).	25650083
Inflammation, Uveitis	Altered Intercellular Communication	These algorithms were then applied to OCT images obtained from uveitis patients with active anterior chamber inflammation.	25650415
Gastric Cardia Carcinoma	Altered Intercellular Communication	Chronic inflammation-related DNA damage response: a driving force of gastric cardia carcinogenesis.	25650663
Aggressive course, Chronic inflammation, Gastric Cardia Carcinoma	Altered Intercellular Communication	Gastric cardia cancer (GCC) is a highly aggressive disease associated with chronic inflammation.	25650663
Inflammation, Cardia of stomach, Gastric Cardia Carcinoma	Altered Intercellular Communication	To investigate the relationship between DNA damage response (DDR) and chronic inflammation, we collected 100 non-tumor gastric cardia specimens of Chaoshan littoral, a high-risk region for esophageal and gastric cardia cancer.	25650663
Inflammation	Altered Intercellular Communication	A significantly higher proportion of severe chronic inflammation was found in dysplastic epithelia (80.9%) in comparison with that in non-dysplastic tissues (40.7%) (P<0.001).	25650663
Inflammation	Altered Intercellular Communication	Immunohistochemical analysis demonstrated that DNA damage response was parallel with the chronic inflammation degrees from normal to severe inflammation (P<0.05).	25650663
Gastric Cardia Carcinoma	Altered Intercellular Communication	These findings provide pathological evidence that persistent chronic inflammation-related DNA damage response may be a driving force of gastric cardia carcinogenesis.	25650663
Inflammation, De Quervain Disease	Altered Intercellular Communication	Inflammation is present in de Quervain Disease--correlation study between biochemical and histopathological evaluation.	25650747
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Previous studies consistently reported that the pathological change of this condition is thought to be primarily an extensor retinaculum thickened by fibrosis and angiogenesis instead of inflammation.	25650747
Glaucoma, Primary Open Angle, Failure, Infection, Conjunctivitis	Altered Intercellular Communication	Being a contributor to low-grade conjunctival inflammation, latent conjunctival CT, and BF infections in primary open-angle glaucoma patients represent risk factors for posttrabeculectomy bleb failure.	25651208
Communicable Diseases, Inflammation, Dermatomycoses	Altered Intercellular Communication	As TLR2 expression acts to limit the inflammatory process and preserves the epidermal structure, its preserved expression may also contribute to the persistent infection and limited inflammation that are characteristic of dermatophytic infections.	25651327
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Prostate cancer has become a public health problem in many countries and there is evidence which indicates that inflammation and oxidative stress play a key role in the pathogenesis of this disease.	25651717
Inflammation, Diabetic Foot	Altered Intercellular Communication	Diabetic foot disease: grading inflammation by apolipoprotein A-I, C-reactive protein and serum amyloid A.	25651728
ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis, Exacerbation	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterised by chronic pulmonary inflammation punctuated by periods of viral exacerbations.	25652132
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Elevated concentrations of inflammatory mediators are characteristic of autoimmune disease accompanied by chronic or recurrent inflammation.	25652333
Inflammation, Lupus Erythematosus, Systemic, Refractory anemias, Rheumatoid Arthritis, Inflammatory disorder, Lupus Erythematosus	Altered Intercellular Communication	We examined the hypothesis that mediators of inflammation known to be elevated in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are associated with genetic polymorphism previously identified in studies of inflammatory disease.	25652333
Refractory anemias, Inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Some genetic associations are more apparent in healthy controls than in SLE or RA, suggesting dysregulation of the principal mediators of chronic inflammation in disease.	25652333
Hyperglycemia, Bothered by Vomiting, Nausea, Inflammatory disease of mucous membrane, Fatigue	Altered Intercellular Communication	The most common treatment-related adverse events (AE) were mucosal inflammation/stomatitis (58.4%), nausea (42.9%), hyperglycemia (26%), decreased appetite (24.7%), fatigue (24.7%), and vomiting (24.7%).	25652454
ARCN1 gene, Inflammation	Altered Intercellular Communication	Loss of GD1-positive Lactobacillus correlates with inflammation in human lungs with COPD.	25652802
Pneumonitis	Altered Intercellular Communication	Primary outcome measure was GD1 positivity within each group and whether or not this impacted quantitative histological measures of lung inflammation.	25652802
ARCN1 gene, Inflammation	Altered Intercellular Communication	Secondary outcome measures included Lactobacillus presence and quantification, and quantitative histological measurements of inflammation and remodelling in early COPD.	25652802
Inflammation, Anxiety, CTCAE 3.0, Depression, CTCAE, Dyspnea, Fatigue	Altered Intercellular Communication	Fatigue, dyspnoea, depression and anxiety, symptom burden, body composition, physical capacity (lung function, exercise capacity, muscle strength), exacerbation rate and systemic inflammation were assessed.	25653122
Anxiety, CTCAE 3.0, Inflammation, Depression, CTCAE	Altered Intercellular Communication	No relationship was found between depression, anxiety, body composition, exacerbation rate or systemic inflammation and PA.	25653122
Low Back Pain, Inflammation, Intervertebral Disk Displacement	Altered Intercellular Communication	Earlier studies indicate that lumbar radicular pain after disc herniation may be associated with a local inflammation induced by leakage of nucleus pulposus (NP) into the spinal canal and neuroforamen.	25653193
Inflammation, Blood coagulation, Headache	Altered Intercellular Communication	Short-term increases in air pollution exposure may trigger headache by increasing pulmonary and systemic inflammation, increasing blood coagulability or altering endothelial function.	25653308
Airway structure	Altered Intercellular Communication	Airway inflammation and ammonia exposure among female Palestinian hairdressers: a cross-sectional study.	25653315
Airway structure	Altered Intercellular Communication	Little is known about the working conditions and airway inflammation in hairdressers in Palestine.	25653315
Airway structure	Altered Intercellular Communication	We aimed to investigate if hairdressers in Palestine have a higher level of airway inflammation as compared to a control group.	25653315
Airway structure	Altered Intercellular Communication	Compared to unexposed controls, the hairdressers had signs of neutrophilic airway inflammation, higher eNO levels and higher CRP.	25653315
Pneumoconiosis, Pneumonitis	Altered Intercellular Communication	Coal workers' pneumoconiosis (CWP) is characterized as a chronic inflammation of the lung associated with activation of macrophages and endothelial cells in the lung.	25653483
Inflammation, CEL gene, Ulcerative Colitis	Altered Intercellular Communication	In contrast, functional analyses of aberrantly expressed genes between UC and FAP samples, irrespective of mucosal inflammation status, revealed multiple pathways and terms that were linked to changes in immune response.	25654358
CEL gene, Ulcerative Colitis	Altered Intercellular Communication	Interestingly, the comparison of uninflamed UC and FAP samples identified a set of 29 altered probe sets, including an inflammation-related transcript encoding a Charcot-Leyden crystal (CLC) protein.	25654358
Inflammation, CEL gene, Ulcerative Colitis	Altered Intercellular Communication	Our study confirmed that alterations in immune responses can be found between patients who underwent surgery for UC and FAP, independent of the pouch inflammation status.	25654358
Inflammation, Acanthosis, Fibrosis Assessment, Hyperplasia	Altered Intercellular Communication	The wound was debrided and pathology showed epithelial hyperplasia, acanthosis, hyperkatosis accompanied by mild inflammation, and fibrosis without any malignant transformation.	25654781
Sinusitis	Altered Intercellular Communication	Nasal endoscopy showed only an intranasal mucosal contact point between the septal crest and the right inferior turbinate, without other signs of sinus inflammation.	25655316
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Patients with increased inflammatory parameters, nonspecific signs and symptoms without fever and without a diagnosis after a variety of diagnostic procedures are a diagnostic dilemma and are referred to as having inflammation of unknown origin (IUO).	25655485
Inflammation, Immune System Diseases	Altered Intercellular Communication	Zinc deficiency results in immune dysfunction and promotes systemic inflammation.	25656040
Inflammation, Humoral immune defect	Altered Intercellular Communication	This work is potentially relevant to the aging population given that age-related immune defects, including chronic inflammation, coincide with declining zinc status.	25656040
Inflammation	Altered Intercellular Communication	Our results suggested potential interactions between zinc status, epigenetics, and immune function, and how their dysregulation could contribute to chronic inflammation.	25656040
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	In the patients with H. pylori infection there was a significant relationship between cagA positivity and neutrophil activity (P = 0.004) and chronic inflammation (P = 0.013) and with H. pylori density (P = 0.034).	25656240
Pancreatitis	Altered Intercellular Communication	Pancreatitis-an inflammation of pancreas-is a severe and costly disease.	25656921
Inflammation, Cellulitis	Altered Intercellular Communication	In this pilot study, we evaluated whether levels of YKL-40, an acute-phase reactant, and mean platelet volume (MPV), which occurs secondary to inflammation in cellulitis, increase compared to healthy subjects.	25657159
Inflammation, Ventricular Dysfunction	Altered Intercellular Communication	The presence of central abdominal fat and systemic inflammation seems implicated in the pathogenesis of vascular dysfunctions in MetS.	25657309
Inflammation, Heart Failure, Systolic	Altered Intercellular Communication	The heart has close interactions with other organs' functions and concomitant systemic factors such as oxidative stress, nitric oxide (NO), inflammation, and nutrition in systolic heart failure (HF).	25658112
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	To identify biomarkers that correlate with pouch inflammation, ulcerative colitis pouch patients were prospectively recruited and underwent clinical, endoscopic, and histologic evaluations.	25659085
Pain Distress Question, Chronic pain	Altered Intercellular Communication	Relationship between blood- and cerebrospinal fluid-bound neurotransmitter concentrations and conditioned pain modulation in pain-free and chronic pain subjects.	25659204
Inflammation	Altered Intercellular Communication	We also found that CMV-seropositivity is associated with increased levels of B cell-intrinsic inflammation and these both correlate with lower B cell function.	25659271
Inflammation, Primary malignant neoplasm, Neoplastic Cell Transformation	Altered Intercellular Communication	Inflammation plays an important role in promoting ovarian tumorigenesis and cancer progression.	25659662
Sepsis, Inflammation, Damage	Altered Intercellular Communication	Excessive inflammation is a major cause of organ damage during sepsis.	25659903
Sepsis, Pneumonitis	Altered Intercellular Communication	In summary, our results suggest that Sirt1 suppresses acute lung inflammation during sepsis by controlling inflammasome activation pathway.	25659903
Inflammation, Abnormality of the hair shaft, Hypergranulosis, Hyperkeratosis	Altered Intercellular Communication	Major histologic and dermatoscopic findings of KP were hyperkeratosis, hypergranulosis, mild T helper cell type 1-dominant lymphocytic inflammation, plugging of follicular orifices, striking absence of sebaceous glands, and hair shaft abnormalities in KP lesions but not in unaffected skin sites.	25660180
Inflammation	Altered Intercellular Communication	L-92 may contribute to the suppression of Th2-dominant inflammation.	25660281
Tissue damage, Tumor necrosis, Chronic disease	Altered Intercellular Communication	Tumor necrosis factor (TNF), a potent inflammatory cytokine, and mitochondrial DNA (mtDNA), a product of inflammation-induced tissue damage, increase with age ("inflammaging") and many chronic diseases.	25660689
Tissue damage, Tumor necrosis, Chronic disease	Altered Intercellular Communication	Tumor necrosis factor (TNF), a potent inflammatory cytokine, and mitochondrial DNA (mtDNA), a product of inflammation-induced tissue damage, increase with age ("inflammaging") and many chronic diseases.	25660689
Inflammation, Inflammatory disorder, Gout	Altered Intercellular Communication	Gout is a polygenic auto-inflammatory disease, in which inflammation plays an important role in disease pathogenesis.	25661540
Inflammation, Immune System Diseases	Altered Intercellular Communication	The cytokine interleukin (IL)-23 promotes inflammation and helps to guide inflammatory cells, while studies have shown that the IL-23R gene is associated with susceptibility to several immune-related diseases.	25661540
Blood capillaries, Blood Clot, Vasculitis, CTCAE	Altered Intercellular Communication	The kidney biopsy revealed diffuse endocapillary proliferation and leukocyte exudation with focal intraluminal hyaline thrombi, prominent tubulointerstitial inflammation, and vasculitis.	25661680
methyldopa, Inflammation	Altered Intercellular Communication	In the pathogenesis of AMD, degeneration of RPE cells by multiple factors including increased oxidative stress and chronic inflammation precedes the irreversible loss of photoreceptors and central vision.	25662315
Inflammation	Altered Intercellular Communication	Here, we report that the plant-derived polyphenol, quercetin, increases viability and decreases inflammation in stressed human ARPE-19 cells after exposure to the lipid peroxidation end product 4-hydroxynonenal (HNE).	25662315
Parkinson Disease, Inflammation, REM Sleep Behavior Disorder	Altered Intercellular Communication	Parkinson disease with REM sleep behavior disorder: features, a-synuclein, and inflammation.	25663225
Parkinson Disease, Inflammation, palladium, REM Sleep Behavior Disorder	Altered Intercellular Communication	To investigate clinical features and potential mechanisms involving a-synuclein oligomer and inflammation in patients with Parkinson disease (PD) and probable REM sleep behavior disorder (PRBD).	25663225
Communicable Diseases, Inflammation	Altered Intercellular Communication	Autophagy, a degradation pathway in which cytoplasmic content is engulfed and degraded by lysosomal hydrolases, plays a pivotal role in infection and inflammation.	25664588
Gastrointestinal inflammation	Altered Intercellular Communication	Heme oxygenase-1 confers protection and alters T-cell populations in a mouse model of neonatal intestinal inflammation.	25665053
Vasculitis	Altered Intercellular Communication	Whole-body CE-MRI with vessel wall imaging detected luminal changes and vessel wall inflammation in TA.	25665823
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	The brains of Alzheimer's disease (AD) patients are characterized by deposits of Abeta peptides and by accompanying chronic inflammation.	25666182
Colitis	Altered Intercellular Communication	Prostaglandin E2 (PGE2) is the dominant prostaglandin in the colon and is associated with colonic inflammation.	25666316
Colitis	Altered Intercellular Communication	Information about the involvement of 15-PGDH in colonic inflammation is sparse.	25666316
Inflammation	Altered Intercellular Communication	With respect to DD, alterations of PGE2-related enzymes suggest that a low PGE2 level may precede the onset of inflammation, thus providing new insight into the pathogenesis of DD.	25666316
Pain Distress Question, Inflammation	Altered Intercellular Communication	The sodium chloride formulation was further tested in rabbits and did not show acute clinical signs of pain or inflammation.	25666331
Inflammation, Dysautonomia, Familial	Altered Intercellular Communication	In addition, biological pathways mainly affected by FD are related to immune response, inflammation, and energetic metabolism.	25666440
Inflammation, Dysautonomia, Familial, Kidney damage	Altered Intercellular Communication	In particular, the up-regulation of uromodulin, prostaglandin H2 d-isomerase and prosaposin in the urine of FD patients was demonstrated; these proteins might be involved in kidney damage at the tubular level, inflammation and immune response.	25666440
Inflammation	Altered Intercellular Communication	Recent studies have suggested that inflammation is a major contributor to WNV encephalitis morbidity.	25667322
Inflammation, Coronary Artery Disease, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a key role in coronary artery disease (CAD) and other manifestations of atherosclerosis.	25668619
Inflammation	Altered Intercellular Communication	Recently, urinary proteins were found to be useful markers for reflecting inflammation status of different organs.	25668619
Gastrointestinal Hemorrhage, Inflammation, Malignant Neoplasms, Neoplasms	Altered Intercellular Communication	To compare Tf and Hb as markers of gastrointestinal hemorrhage, we conducted a quantitative enzyme-linked immunosorbent assay (ELISA) for both proteins in 53 cases, with subsequent analysis based on lesion groups (malignant tumor, benign tumor, or inflammation).	25669034
Autoimmune Diseases, Communicable Diseases, Malignant Neoplasms	Altered Intercellular Communication	The erythrocyte sedimentation rate (ESR) has been used as an index for inflammatory conditions, such as infectious diseases, autoimmune diseases, and malignancies.	25669035
Communicable Diseases, Granulomatous, Pneumonitis	Altered Intercellular Communication	However, increased 18 F-FDG uptake was also seen in benign lesions such as active pulmonary inflammation or infection, granulomatous processes and fibrotic lesions.	25669335
Inflammation, Native Valve Endocarditis	Altered Intercellular Communication	Performing a reoperative root replacement in cases of prosthetic valve endocarditis (PVE) can often be challenging due to significant inflammation and scarring.	25669643
Inflammation, Autistic Disorder	Altered Intercellular Communication	The etiology of autism is poorly understood, the evidence indicates that inflammation may play a key role.	25669692
Inflammation, Autistic Disorder, Abnormal digestive tract function	Altered Intercellular Communication	In autism a high prevalence of gastrointestinal disturbances is reported, that are linked to a low-grade chronic inflammation of the intestinal mucosa.	25669692
Inflammation, Autistic Disorder	Altered Intercellular Communication	Results of the study support the involvement of the systemic low-grade inflammation in the pathomechanisms of autism and its possible association with GI symptoms.	25669692
Liver carcinoma, FAM126A gene	Altered Intercellular Communication	Several papers have shown that preoperative inflammation-based prognostic scores and/or immunonutritional status are associated with survival in patients with hepatocellular carcinoma (HCC).	25670038
Inflammation, diabetic	Altered Intercellular Communication	Data reported in the present study, together with the results of previous studies, further support a relationship between glycemic control and periapical inflammation in diabetic patients.	25670246
Inflammation, Cardiac function	Altered Intercellular Communication	Characteristics regarding general condition, inflammation, and cardiac and renal function were the decisive factors of NT-proBNP (P<0.05 for all).	25670892
Airway structure, ARCN1 gene	Altered Intercellular Communication	Airway inflammation in Japanese COPD patients compared with smoking and nonsmoking controls.	25670894
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	To assess the importance of inflammation in chronic obstructive pulmonary disease (COPD) by measuring airway and systemic inflammatory biomarkers in Japanese patients with the disease and relevant control groups.	25670894
ARCN1 gene, Inflammation, Airway Obstruction	Altered Intercellular Communication	These results provide evidence for the first time that COPD in Japanese patients is a multicomponent disease, involving both airway and systemic inflammation, in addition to airway obstruction.	25670894
Inflammation, Panniculitis, Systemic disease	Altered Intercellular Communication	Panniculitis is an inflammation of the subcutaneous adipose tissue and can be associated with systemic diseases.	25671441
Inflammation, Neoplasms	Altered Intercellular Communication	Galectins affect diverse physiological and pathophysiological processes such as development, inflammation, and tumor growth.	25672239
Sepsis, Inflammation	Altered Intercellular Communication	Although there seems to be some connection between vaspin and inflammation, its role in human sepsis needs to be evaluated further.	25672472
Inflammation, Tuberculosis	Altered Intercellular Communication	Interventions that decrease inflammation while promoting cellular immune recovery during ART should be considered in patients co-infected with HIV and tuberculosis.	25672566
Airway structure, Aortic Stiffness	Altered Intercellular Communication	Aortic stiffness, an independent predictor of cardiovascular risk, and systemic and airway inflammation are increased in patients with the disease.	25673981
Airway structure, Chronic Obstructive Airway Disease, Aortic Stiffness	Altered Intercellular Communication	A proof-of-principle, double-blind, randomized trial determined if 6 weeks of simvastatin 20 mg once daily reduced aortic stiffness and systemic and airway inflammation in patients with chronic obstructive pulmonary disease.	25673981
ARCN1 gene, Inflammation, Osteoporosis, Osage language, Sleep Apnea, Obstructive	Altered Intercellular Communication	Worse systemic inflammation and reduced exercise capacity have been reported in COPD patients with obstructive sleep apnea (OSA), implying that OSA may be an independent factor for osteoporosis in COPD patients.	25673983
Deglutition Disorders, Neck muscle weakness, Dysarthria, CTCAE, Mitochondrial Myopathies	Altered Intercellular Communication	After treated with prednisone, the symptoms of dysphagia, dysarthria and neck muscle weakness were significantly improved, and the second biopsy showed only mitochondrial myopathy pathology but the inflammations disappeared.	25674260
Inflammatory Bowel Diseases	Altered Intercellular Communication	Inflammatory bowel disease (IBD) is an inflammatory condition of the digestive tract not caused by infectious agents.	25674731
Cessation of life, Pathology	Altered Intercellular Communication	The implication of the neuromodulator serotonin also in the aetiology of sudden unexplained fetal and infant death syndromes and the demonstration in these pathologies of developmental alterations of the superior olivary complex (SOC), a group of pontine nuclei likewise involved in hearing, prompted us to investigate whether the inferior colliculus may somehow contribute to the pathogenetic mechanism of unexplained perinatal death.	25674737
vascular inflammations, Iliac Aneurysm	Altered Intercellular Communication	Vascular inflammation in a growing iliac artery aneurysm.	25674872
Inflammation	Altered Intercellular Communication	The combined PET and MRI evaluation of inflammation that we present here is a novel approach to vascular imaging that is well suited for emerging hybrid PET/MRI systems.	25674872
Inflammation, Anemia, Comorbidity	Altered Intercellular Communication	Most anaemias are due to a deficiency, chronic inflammation or comorbidity.	25675644
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) and tumor necrosis factor superfamily member 15 (TNFSF15), members of the TNF superfamily, play important roles in the modulation of inflammation and neovascularization.	25676319
Inflammation, PDR gene	Altered Intercellular Communication	Our findings suggest that TNFSF15 and the TWEAK/Fn14 pathway are novel mediators involved in persistent inflammation and modulation of pathological neovascularization associated with PDR.	25676319
Inflammation	Altered Intercellular Communication	Adiposity Alters Genes Important in Inflammation and Cell Cycle Division in Human Cumulus Granulosa Cell.	25676576
Inflammation, Obesity	Altered Intercellular Communication	To determine whether obesity alters genes important in cellular growth and inflammation in human cumulus granulosa cells (GCs).	25676576
Inflammation, Obesity	Altered Intercellular Communication	Adiposity is associated with changes in the expression of genes important in cellular growth, cell cycle progression, and inflammation.	25676576
Inflammation	Altered Intercellular Communication	The mechanisms leading to systemic inflammation after chloroform intoxication are currently unclear.	25676899
Inflammation, Scotoma, Central, Retinitis Pigmentosa	Altered Intercellular Communication	These results suggest a close relationship between inflammation and central vision loss in RP.	25677184
Cataract, Intraocular inflammation	Altered Intercellular Communication	Monitoring of best-corrected visual acuity, intraocular inflammation, cataract progression, and retinal structure by spectral domain optical coherence tomography was done at 1 day and 1 week after injection.	25677668
methyldopa, Intraocular inflammation, retinal toxicity	Altered Intercellular Communication	There were no signs of retinal toxicity, intraocular inflammation or change in lens status in four eyes with AMD and two eyes with DME.	25677668
Inflammation, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	On the other hand, lower SALs are due to obesity, inflammation and presence of already 2 components of metabolic syndrome.	25677829
Inflammation, Neoplasms	Altered Intercellular Communication	* Focal marginal uptake can be due to recurrent tumour or inflammation.	25678079
Inflammation	Altered Intercellular Communication	Evidence suggests that the COX-2 pathway, an important component of inflammation, may be involved in the disease.	25679523
Neurodegenerative Disorders, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) is a neurodegenerative disorder involving impaired cholinergic neurotransmission and dysregulation of nicotinic acetylcholine receptors (nAChRs).	25680266
Malnutrition	Altered Intercellular Communication	Malnutrition was evaluated through subjective global assessment (SGA) and malnutrition inflammation score (MIS).	25680525
Inflammation, Malignant Neoplasms, Squamous cell carcinoma of the head and neck	Altered Intercellular Communication	Change of maximum standardized uptake value slope in dynamic triphasic [18F]-fluorodeoxyglucose positron emission tomography/computed tomography distinguishes malignancy from postradiation inflammation in head-and-neck squamous cell carcinoma: a prospective trial.	25680593
Cholecystitis, Fibrosis Assessment, Phlebitis	Altered Intercellular Communication	Immunoglobulin (Ig)G4-associated cholecystitis is also a newly described cholecystitis variant characterized by transmural or extramural lymphoplasmacytic inflammation, lymphoid follicles, storiform fibrosis, phlebitis, and increased tissue IgG4-positive plasma cells.	25680903
Inflammation	Altered Intercellular Communication	Hypo-osmotic shock-induced subclinical inflammation of skin in a rat model of disrupted skin barrier function.	25681269
Shock, Dermatitis	Altered Intercellular Communication	We conducted the present study to test the hypothesis that hypo-osmotic shock of epidermal cells induces skin inflammation and elongation of C-fibers by nerve growth factor b (NGFb) as a basic mechanism of APE.	25681269
ARCN1 gene, Chronic Obstructive Airway Disease, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by neutrophil-dominated airway mucosal inflammation and elevated neutrophil counts in sputum and lung tissue.	25681277
Inflammation, Fatty degeneration	Altered Intercellular Communication	Nonspecific abnormalities alone were seen in 22 (35%) subjects, including mild steatosis, mild to moderate inflammation, and evidence of drug adaptation.	25681381
Interstitial inflammation	Altered Intercellular Communication	Histologic plugs were similar in UA and CaOx SF, although CaOx SF demonstrated greater interstitial inflammation on endoscopic biopsy.	25681832
Inflammation, Atherosclerosis	Altered Intercellular Communication	Autoimmune responses against oxidized-LDL (oxLDL) have been suggested to modulate inflammation in atherosclerosis.	25682025
Inflammation, Peripheral Arterial Diseases, Coronary Artery Disease	Altered Intercellular Communication	Systemic inflammation is higher in peripheral artery disease than in stable coronary artery disease.	25682027
Inflammation, Peripheral Arterial Diseases, Coronary Artery Disease	Altered Intercellular Communication	The knowledge on the level of systemic inflammation in peripheral artery disease (PAD) is less well established than that in coronary artery disease (CAD).	25682027
Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Atherosclerosis	Altered Intercellular Communication	Systemic inflammation frequently coincides with atherosclerosis, but also with various traits of the metabolic syndrome (MetS).	25682027
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	The individual contribution of CAD, PAD, and the MetS to inflammation is not known.	25682027
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Low grade systemic inflammation is independently associated with both the MetS and PAD.	25682027
Inflammation, Cardiovascular Diseases, Atherosclerosis	Altered Intercellular Communication	Relationship of pericardial fat with biomarkers of inflammation and hemostasis, and cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis.	25682037
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Pericardial fat may increase the risk of cardiovascular disease (CVD) by increasing circulating levels of inflammation and hemostasis biomarkers.	25682037
Inflammation, Obesity, Abdominal, Periodontal Diseases	Altered Intercellular Communication	Abdominal obesity and periodontal diseases are believed to share close relation through commonality of chronic inflammation.	25682300
Inflammation, Breast Carcinoma	Altered Intercellular Communication	To investigate the possible role of deleted in breast cancer 1 (DBC1) in adipocyte and adipose tissue inflammation.	25682741
Inflammation, Metabolic Syndrome X, Atherosclerosis, Non-alcoholic Fatty Liver Disease, Obesity	Altered Intercellular Communication	The association of nonalcoholic fatty liver disease, obesity, and metabolic syndrome, with systemic inflammation and subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis (MESA).	25683387
Inflammation, Metabolic Syndrome X, Atherosclerosis, Non-alcoholic Fatty Liver Disease, Obesity	Altered Intercellular Communication	We characterized the association of 3 metabolic conditions - obesity, metabolic syndrome, and nonalcoholic fatty liver disease (NAFLD) - with increased inflammation and subclinical atherosclerosis.	25683387
Inflammation, SLC25A20 gene, Atherosclerosis	Altered Intercellular Communication	Increased inflammation was defined as high sensitivity C-reactive protein (hsCRP) >=2 mg/L and subclinical atherosclerosis as coronary artery calcium (CAC) > 0.	25683387
Inflammation, SLC25A20 gene	Altered Intercellular Communication	We studied the association of a stepwise increase in number of these metabolic conditions (0-3) with increased inflammation and CAC, stratifying results by gender and ethnicity.	25683387
Inflammation, SLC25A20 gene, Metabolic Syndrome X, Non-alcoholic Fatty Liver Disease, Obesity	Altered Intercellular Communication	NAFLD is associated with increased inflammation and CAC independent of traditional risk factors, obesity and metabolic syndrome.	25683387
Inflammation, SLC25A20 gene, Metabolic Syndrome X, Non-alcoholic Fatty Liver Disease, Obesity	Altered Intercellular Communication	There is a graded association between obesity, metabolic syndrome, and NAFLD with inflammation and CAC.	25683387
Inflammation, Depression, CTCAE, Coronary heart disease	Altered Intercellular Communication	Insufficient glucocorticoid signaling and elevated inflammation in coronary heart disease patients with comorbid depression.	25683698
Inflammation, Depression, CTCAE, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	In conclusion, CHD patients with depression had elevated levels of inflammation in the context of HPA axis hypoactivity, GR resistance, and increased activation of the kynurenine pathway.	25683698
Neoplasms, Colitis	Altered Intercellular Communication	Immunohistochemical expression of SP-NK-1R-EGFR pathway and VDR in colonic inflammation and neoplasia.	25684939
Weight Gain, Inflammation	Altered Intercellular Communication	Relationship between relative interdialytic weight gain and serum leptin levels, nutrition, and inflammation in chronic hemodialysis patients.	25685870
HD Term Type, Inflammation	Altered Intercellular Communication	We aimed to assess the relationship between RIDWG and appetite, nutrition, inflammation parameters of chronic HD patients.	25685870
Inflammation, Dental Plaque, Dental caries, Osage language	Altered Intercellular Communication	OSA subjects had less dental caries, plaque deposition, and gingival inflammation and better oral hygiene.	25685971
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular hypotony in PHA was thought to be due to intra-ocular inflammation.	25686066
Unknown (origin) (qualifier value), Inflammation, Cerebellar Ataxia	Altered Intercellular Communication	Acute or subacute cerebellar inflammation is mainly caused by postinfectious, toxic, neoplastic, vascular, or idiopathic processes and can result in cerebellar ataxia.	25686577
Inflammation, Virus Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Increased risk of cardiovascular disease in patients infected with HIV has been attributed to immune activation, inflammation, and immunosenescence, all of which are linked to chronic immune activation by viral infections, particularly cytomegalovirus (CMV).	25686677
Inflammation, Intestines, Small	Altered Intercellular Communication	Xanthogranulomatous inflammation of terminal ileum: report of a case with small bowel involvement.	25686705
Inflammation	Altered Intercellular Communication	Xanthogranulomatous inflammation is a rare pathological condition most frequently detected in the kidney and gallbladder.	25686705
Xanthogranulomatous inflammation	Altered Intercellular Communication	Reported herein is a case of xanthogranulomatous inflammation in a 51-year-old male presenting as a mass-forming lesion in the terminal ileum with mucosal ulceration.	25686705
Xanthogranulomatous inflammation, gastrointestinal	Altered Intercellular Communication	This is a report of the condition involving the terminal ileum with mucosal ulceration and full-thickness involvement of bowel wall which are uncommon features of xanthogranulomatous inflammation in previously reported lower gastro-intestinal tract lesions.	25686705
Sarcoidosis, Inflammatory abnormality of the eye	Altered Intercellular Communication	Sarcoidosis in the national veteran population: association of ocular inflammation and mortality.	25687027
Sarcoidosis, Inflammatory abnormality of the eye, Orbital Pseudotumor, Uveitis	Altered Intercellular Communication	The sarcoidosis patients were divided into those with uveitis or orbital inflammation (defined as ocular inflammation for this study) and those without uveitis or orbital inflammation.	25687027
Inflammatory abnormality of the eye	Altered Intercellular Communication	Association between ocular inflammation and 1-year mortality.	25687027
Anterior uveitis, Inflammatory abnormality of the eye, Orbital granuloma	Altered Intercellular Communication	Most patients were diagnosed with anterior uveitis (n = 1013; 80.7% of ocular inflammation), and the least common diagnosis was orbital granuloma (n = 28; 2.2% of ocular inflammation).	25687027
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation was associated with a decrease in 1-year all-cause mortality (simple model: hazard ratio, 0.36; P = 0.0015; complex model: hazard ratio, 0.35; P = 0.013).	25687027
Inflammatory abnormality of the eye	Altered Intercellular Communication	Veterans with ocular inflammation had significantly lower 1-year all-cause mortality than those without documented ocular inflammation.	25687027
Airway structure, Asthma	Altered Intercellular Communication	Our objective was to determine what impact the level of air pollutants had on the control of their asthma and the degree of airway inflammation.	25687770
Airway structure, Asthma	Altered Intercellular Communication	Disease control was assessed using asthma control test (ACT) scores, and airway inflammation using fraction of exhaled nitric oxide (FeNO) values.	25687770
Airway structure	Altered Intercellular Communication	We found no relationship between pollutants and airway inflammation.	25687770
Inflammation, Disorder of the optic nerve	Altered Intercellular Communication	A retrospective chart review was conducted on patients with glaucomatous optic neuropathy, chronic anterior or posterior segment inflammation, and >=6 months postoperative follow-up.	25688057
Inflammation	Altered Intercellular Communication	Inflammation plays an important role in the pathophysiology of CI-AKI.	25688117
Inflammation, Malnutrition, Atherosclerosis, HD Term Type, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	NAFLD may be the missing link that causally ties malnutrition, inflammation, and atherosclerosis syndrome to the morbidity and mortality in patients undergoing HD.	25688578
Inflammatory disease of mucous membrane	Altered Intercellular Communication	CCR6 is a chemokine receptor involved in homing memory T cells, particularly Th17 cells, to sites of mucosal inflammation.	25690781
Inflammation, Hydronephrosis	Altered Intercellular Communication	We hypothesize that the obstruction and absence of hydronephrosis were caused by extrinsic compression and subsequent inflammation due to the fibrin glue.	25694019
Giant Cell Arteritis, vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Both atherosclerosis and giant cell arteritis cause vascular inflammation, but distinguishing the two may be difficult.	25695092
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	An antagonist (MK-7123) of the cytokine receptor CXCR2 reduces neutrophil chemotaxis and thus may alleviate airway inflammation in chronic obstructive pulmonary disease (COPD).	25695403
Inflammation, Malignant neoplasm of endometrium, Endometriosis	Altered Intercellular Communication	Nonetheless, endometriosis may also be associated with endometrial cancer because of shared etiological mechanisms of both estrogen stimulation and chronic inflammation; however, the association between these 2 disorders has rarely been investigated.	25695548
Inflammation, Metabolic Diseases, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	Body fat distribution and inflammation may play a role in metabolic derangements and cardiovascular disease in obesity.	25695885
Hypertensive disease, Inflammation	Altered Intercellular Communication	[Serum markers of inflammation and lipid-releasing ability of leukocytes in patients with arterial hypertension and angina of effort].	25696963
Inflammation, Hypertension, CTCAE, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	The aim of the present work was to investigate serum markers of inflammation and LRAL in arterial hypertension (AH) without coronary heart disease (CHD) or AH + angina of effort.	25696963
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Inflammation and angiogenesis play an important role in atherosclerotic plaque rupture.	25698472
Edema	Altered Intercellular Communication	Macular edema (ME) resulted to be associated to chronic postoperative inflammation (r = 0.6; p = 0.00) and mostly related to patients who presented more than one postoperative relapse/year (r = 0.2; p = 0.02).	25700154
Inflammatory abnormality of the eye	Altered Intercellular Communication	There was no case in which ocular inflammation was exacerbated by surgical stress.	25700328
Ocular sarcoidosis, Inflammatory abnormality of the eye	Altered Intercellular Communication	Improvement of visual acuity and resolution of ocular inflammation could be achieved by MIVS using wide-viewing system for complications of ocular sarcoidosis.	25700328
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Inflammation is increasingly implicated as a mediating factor relating stress to physical disease and is strongly linked to depression.	25700535
Inflammation	Altered Intercellular Communication	Inflammation may, therefore, be implicated in processes associated with excess mortality and morbidity during unemployment.	25700535
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	There is no correlation between peripheral inflammation and cognitive status at diagnosis in Alzheimer's disease.	25700558
Inflammation	Altered Intercellular Communication	C-reactive protein >10 mg/L and any acute or chronic inflammation were considered as exclusion criteria.	25700558
Generalized osteoarthritis, Inflammation, Degenerative polyarthritis, Metabolic Syndrome X	Altered Intercellular Communication	Generalized, polyarticular osteoarthritis and local, monoarticular osteoarthritis appear to be two different profiles; the former is a feature of osteoarthritis co-morbid with inflammation or the metabolic syndrome, while the latter is more typical of post-trauma osteoarthritis, especially in cases with severe malalignment.	25701074
Inflammation, Pseudoepitheliomatous hyperplasia	Altered Intercellular Communication	Histological examination showed pseudoepitheliomatous hyperplasia and severe submucosal inflammation with ovoid budding yeasts by Grocott's stain.	25701260
Coronary Artery Disease	Altered Intercellular Communication	Inflammation mediators have been recognized as risk factors for the pathogenesis of coronary artery disease (CAD).	25701337
Inflammation, Endothelial dysfunction, metabolic disturbance	Altered Intercellular Communication	At elevated concentrations, circulating leptin has been associated with metabolic disturbances, namely insulin resistance, elevated blood pressure, inflammation, and endothelial dysfunction.	25701340
Inflammation, Necrosis	Altered Intercellular Communication	Stage I was defined by focal inflammation without necrosis (n = 2); stage II by focal clusters of micro-abscesses appearing to coalesce (n = 41); and stage III by a single cavity with or without capsule (n = 64).	25701525
Inflammation	Altered Intercellular Communication	Histology of the biopsies from this site revealed chronic inflammation and reactive changes.	25701830
Inflammation, Intestine Resection, Malignant Neoplasms	Altered Intercellular Communication	Postoperatively, histology of resected bowel revealed chronic inflammation and no evidence of malignancy.	25701830
Hypernatremia, Inflammation, CORO1A gene, Transfusion Reaction, Transfusion-Related Acute Lung Injury	Altered Intercellular Communication	We hypothesized that biologic markers of inflammation could be used in conjunction with clinical predictors to distinguish transfusion-related acute lung injury (TRALI), transfusion-associated circulatory overload (TACO), and possible TRALI.	25702590
Inflammation, CORO1A gene, Transfusion-Related Acute Lung Injury	Altered Intercellular Communication	Before transfusion, there is evidence of systemic inflammation in patients who develop TRALI and possible TRALI but not TACO.	25702590
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Glycemic control, inflammation, and cognitive function in older patients with type 2 diabetes.	25703191
Inflammation, Musculoskeletal torsion, function	Altered Intercellular Communication	We postulate that the constriction caused by inflammation is the precursor of torsion and that development of nerve torsion is facilitated by the rotational movements of limbs.	25703205
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The posterior falx and tentorium showing a hypointense center ("fibrosis") and enhancing periphery ("active inflammation") together mimicking "Eiffel-by-night" sign was found to be more commonly associated with IHP (60% vs 12.5%, p=0.03).	25703277
Increased insulin level, Inflammation, Neoplasms, Obesity	Altered Intercellular Communication	Obesity is associated with increased bioavailability of estrogen, hyperinsulinemia, and chronic inflammation, all of which may promote tumor growth.	25703993
Inflammation, Muscular Dystrophy, Facioscapulohumeral	Altered Intercellular Communication	We found no difference in the frequency of inflammation between FSHD types 1 and 2.	25704033
Inflammation, PLAU protein, human, Lung Injury	Altered Intercellular Communication	Urokinase-type plasminogen activator (uPA) augments inflammation and tissue remodeling during lung injury and repair.	25706093
Inflammation, Electrocardiogram: myocardial infarction (finding), Atherosclerosis	Altered Intercellular Communication	SIRT1 exerts protective effects against endothelial cells dysfunction, inflammation and atherosclerosis, indicating an important role on myocardial infarction (MI) pathogenesis.	25706717
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Serum albumin is a widely acceptable method of assessing nutritional and inflammation status in cancer patients.	25706773
Inflammation, Infection	Altered Intercellular Communication	Immunity-related GTPase family M (IRGM) is a human protein highlighted for its contribution to autophagy upon inflammation and infections.	25707354
Inflammation, Fracture	Altered Intercellular Communication	We hypothesized that intraarticular fracture would alter the synovial environment and lead to increased local and systemic inflammation.	25707992
Inflammation, Intra-Articular Fractures, Synovitis	Altered Intercellular Communication	Articular fracture of the ankle increased acute local inflammation, as indicated by increased synovitis, increased macrophage infiltration into synovial tissue, and increased SF concentrations of biomarkers of inflammation.	25707992
vascular inflammations	Altered Intercellular Communication	Vaspin is an adipokine implicated in vascular inflammation and remodeling.	25708680
Inflammation, Chronic Obstructive Airway Disease, heart overload	Altered Intercellular Communication	Even in patients with stable chronic obstructive pulmonary disease, the serum troponin T concentration was controlled by at least three major factors, ie, systemic inflammation, advancing age, and right cardiac overload.	25709425
Bacterial Infections	Altered Intercellular Communication	Soluble urokinase-type plasminogen activator receptor (suPAR) levels increase in acute viral and bacterial infections and in diseases involving chronic inflammation.	25709430
ARCN1 gene, Chronic Obstructive Airway Disease, exacerbation acute	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory condition, and progresses with acute exacerbations.	25709430
Inflammation, Herpes	Altered Intercellular Communication	HCMV, like all other herpes viruses, has the ability to remain latent within the body of the host and can contribute in chronic inflammation.	25710012
Presenile dementia, Inflammation	Altered Intercellular Communication	Cerebral Amyloid Angiopathy-related Inflammation Presenting With Rapidly Progressive Dementia, Responsive to IVIg.	25710131
Inflammation, Observation Method - Coagulation, Atherosclerosis	Altered Intercellular Communication	Long-term exposure to air pollution and markers of inflammation, coagulation, and endothelial activation: a repeat-measures analysis in the Multi-Ethnic Study of Atherosclerosis (MESA).	25710246
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Air pollution is associated with cardiovascular disease, and systemic inflammation may mediate this effect.	25710246
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	We assessed associations between long- and short-term concentrations of air pollution and markers of inflammation, coagulation, and endothelial activation.	25710246
vascular inflammations	Altered Intercellular Communication	Diverging trajectory patterns of systemic versus vascular inflammation over age in healthy Caucasians and African-Americans.	25710295
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Age and inflammation are risk factors for cardiovascular disease but the impact of inflammation on cardiovascular risk across the lifespan is not understood.	25710295
Inflammation, vascular inflammations	Altered Intercellular Communication	The composite z-score for systemic inflammation increased with age, while the composite z-score for vascular inflammation declined with age, irrespective of ethnicity.	25710295
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Interleukin (IL-15), a pro-inflammatory cytokine has been studied as a possible marker of Alzheimer's disease (AD); however its exact role in neuro-inflammation or the pathogenesis AD is not well understood yet.	25710473
Adenocarcinoma, Inflammation, Serrated adenocarcinoma	Altered Intercellular Communication	Moreover, morphologic features significantly associated with BRAF mutation were: serrated adenocarcinoma subtype, adenocarcinomas with a mucinous component, high histologic grade, pushing margins, stromal inflammation.	25710585
Interictal epileptiform activity	Altered Intercellular Communication	Periodic lateralized epileptiform discharges may arise by synchronization of preexisting local field potentials, through a variable combination of enhancement of excitatory neurotransmission and inactivation of inhibitory neurotransmission provoked by the PLED-associated disease process.	25710632
Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Purpura	Altered Intercellular Communication	Leukocytoclastic vasculitis (LCV), a disease characterized by inflammation of the small vessels, presents with palpable purpura, especially in the lower extremities.	25711253
Allergic sensitization, Inflammation	Altered Intercellular Communication	Both facilitated allergen sensitization and secondary degradation of filaggrin following T-helper cell 2 inflammation might be key elements to understanding this relationship.	25712346
Inflammation, Primary malignant neoplasm, Hypoxia	Altered Intercellular Communication	Excess visceral adipose tissue may promote cancer development and progression via an obesity-related metabolic derangements, including adipocytokine-related inflammation, insulin resistance, and hypoxia.	25712800
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Regular aspirin use may decrease cancer risk by reducing chronic inflammation.	25713025
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Additional studies are needed to better understand the relationship between aspirin use, chronic inflammation, and cancer risk.	25713025
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Neopterin may be relevant for colorectal cancer (CRC) development, as a biomarker of cellular immune activity exerting pleiotropic effects on cellular ageing, oxidative stress, and inflammation.	25713165
Inflammation, Blood Clot	Altered Intercellular Communication	Moreover, the nonhomogeneous ISR image visualized by OCT may show chronic inflammation and fibrin thrombi.	25714072
Hypernatremia, Inflammation, physiopathological, Obesity, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Lipid overload in obesity and type 2 diabetes is associated with adipocyte dysfunction, inflammation, macrophage infiltration, and decreased fatty acid oxidation (FAO).	25714670
Inflammation, Comorbidity	Altered Intercellular Communication	Within-person variation was unaffected by dialysis modality, hydration status, inflammation, or cardiac comorbidity.	25714960
Esophageal Stricture, Inflammation, Acid reflux	Altered Intercellular Communication	We present a novel finding of multinucleated histiocytes associated with acute and chronic inflammation secondary to gastroesophageal reflux in a patient with a history of esophageal stricture, representing the first documented case after a review of the literature.	25715818
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	The rats exposed to PHMG-phosphate aerosol particles in nanometer size showed pulmonary inflammation and fibrosis including inflammatory cytokines and fibronectin mRNA increase, as well as histopathological changes.	25716161
Destruction of tissue, Inflammation	Altered Intercellular Communication	A simultaneous state of tissue destruction and inflammation caused by PHMG-phosphate had whipped up a "perfect storm" in the respiratory tract.	25716161
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Factors such as inflammation, the presence of heart fibrosis, stress and cardiomyocyte apoptosis, have all been associated with AF.	25716679
Vasculitis	Altered Intercellular Communication	The existing donor-specific antibodies or moderate microvascular inflammation or C4d-positive staining or intensive tubulointerstitial inflammation played a less significant role on the long-term graft survival.	25719260
Inflammation, Overweight	Altered Intercellular Communication	Glucosamine and chondroitin supplementation may lower systemic inflammation and alter other pathways in healthy, overweight individuals.	25719429
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation is critical to the pathogenesis and progression of cancer, with a high neutrophil-lymphocyte ratio (NLR) associated with poor prognosis.	25719834
Communicable Diseases, Inflammation	Altered Intercellular Communication	Focal exuberant soft-tissue proliferation around the buckle was present in all patients, suggesting chronic inflammation and infection.	25719983
Granulomatous inflammation, Endophthalmitis	Altered Intercellular Communication	Evaluation of the 16 enucleated inciting eyes (blind and painful) disclosed that 9 of the 16 had typical histology, fulfilling the criteria for sympathetic ophthalmia of diffuse granulomatous inflammation.	25719985
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Many lymph nodes showed histologic findings of granulomatous inflammation with necrosis.	25720029
Inflammation, Data types - Address	Altered Intercellular Communication	Inflammation and immune alterations have been linked to AD, suggesting that the peripheral immune system plays a role during the asymptomatic period of AD.	25720398
Mastitis, Menopause	Altered Intercellular Communication	Menopause is a determinant of breast adipose inflammation.	25720743
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Chronic inflammation is recognized as a risk factor for the development of several malignancies.	25720743
Inflammation, Malignant neoplasm of breast	Altered Intercellular Communication	The associated increased levels of aromatase in the breast provide a plausible mechanistic link between WAT inflammation and estrogen-dependent breast cancers.	25720743
Mastitis, Neoplasms	Altered Intercellular Communication	Thus, breast WAT inflammation could be relevant for explaining the high incidence of estrogen-dependent tumors with aging despite diminished circulating estrogen levels after menopause.	25720743
Mastitis	Altered Intercellular Communication	In multivariable analyses adjusted for BMI, the postmenopausal state was independently associated with the presence (P = 0.03) and severity of breast WAT inflammation (P = 0.01).	25720743
Mastitis	Altered Intercellular Communication	Our findings demonstrate that breast WAT inflammation, which is associated with elevated aromatase levels, is increased in association with the postmenopausal state independent of BMI.	25720743
Mastitis, Neoplasms	Altered Intercellular Communication	Breast WAT inflammation, a process that can potentially be targeted, may help to explain the high incidence of estrogen-dependent tumors in postmenopausal women.	25720743
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Immediate postoperative inflammation is an important prognostic factor in breast cancer.	25721153
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation is associated with worse outcomes in cancer.	25721153
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Immediate postoperative inflammation is an important prognostic marker in breast cancer patients.	25721153
Inflammation, Degenerative disorder	Altered Intercellular Communication	The rate of inflammation increases in elderly individuals, a phenomenon called inflammaging, and is associated with degenerative diseases.	25721217
Inflammation	Altered Intercellular Communication	Number of sons contributes to ageing-associated inflammation.	25721217
Inflammation, Degenerative disorder	Altered Intercellular Communication	The rate of inflammation increases in elderly individuals, a phenomenon called inflammaging, and is associated with degenerative diseases.	25721217
Inflammation, Intradermal Route of Drug Administration	Altered Intercellular Communication	Using the higher SF cut-off method resulted in the highest ID prevalence (52.1%), followed by using two different cut-offs (31.8%), using CFs (21.9%) and excluding subjects with inflammation (17.6%).	25721990
Fatty Liver, Inflammation, Metabolic Diseases, Obesity	Altered Intercellular Communication	Obesity is a major risk factor for many chronic metabolic diseases such as inflammation, insulin resistance (IR) and fatty liver injury.	25723054
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	Our results suggest that SpA can regulate the pathogenesis of enterotoxin-induced inflammation in patients with chronic rhinosinusitis with nasal polyps through coupling to immunoglobulins.	25724120
Inflammation, Demyelination, MS gene, response to axon injury	Altered Intercellular Communication	Differentiation and quantification of inflammation, demyelination and axon injury or loss in multiple sclerosis.	25724201
Inflammation, Demyelination, Multiple Sclerosis, Pathology	Altered Intercellular Communication	Axon injury/loss, demyelination and inflammation are the primary pathologies in multiple sclerosis lesions.	25724201
Inflammation, Demyelination, MS gene	Altered Intercellular Communication	An imaging modality capable to effectively detect, differentiate and individually quantify axon injury/loss, demyelination and inflammation, would not only facilitate the understanding of the pathophysiology underlying multiple sclerosis progression, but also the assessment of treatments at the clinical trial and individual patient levels.	25724201
Vasogenic Edema	Altered Intercellular Communication	Through the multiple-tensor modelling of diffusion weighted magnetic resonance imaging signals, diffusion basis spectrum imaging resolves inflammation-associated cellularity and vasogenic oedema in addition to accounting for partial volume effects resulting from cerebrospinal fluid contamination, and crossing fibres.	25724201
Edema	Altered Intercellular Communication	Diffusion basis spectrum imaging-derived radial diffusivity (myelin integrity marker) and non-restricted isotropic diffusion fraction (oedema marker) correlated with magnetization transfer ratio, supporting previous reports that magnetization transfer ratio is sensitive not only to myelin integrity, but also to inflammation-associated oedema.	25724201
Inflammatory disease of mucous membrane, Protein-Losing Enteropathies	Altered Intercellular Communication	An abdominal dynamic scintigraphy and colonoscopy findings indicated protein-losing enteropathy with nonspecific mucosal inflammation.	25724370
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Effects of nondipping pattern on systemic inflammation in obstructive sleep apnea.	25724552
Inflammation	Altered Intercellular Communication	These results demonstrate that MAA adducts are associated with AAA and suggest that they may play a role in either initiating or propagating chronic inflammation in AAA.	25724613
Myocarditis	Altered Intercellular Communication	Although this might reflect continued emotional stress, myocardial inflammation and accentuated brain-type natriuretic peptide (BNP) release persist for at least 3 months.	25724780
Myocarditis	Altered Intercellular Communication	In conclusion, despite normalization of left ventricular ejection fraction, GLS remains impaired for at least 3 months, possibly as a result of residual myocardial inflammation.	25724780
Inflammation, Dental Plaque	Altered Intercellular Communication	Examination demonstrated a fluffy white infiltrate and epithelial defect with subsequent endothelial plaque formation and anterior chamber inflammation.	25725025
Respiratory complication, Inflammation, Airway structure, Fibrosis Assessment, Hemoptysis	Altered Intercellular Communication	Cystic fibrosis (CF) is characterized by airway infection and inflammation resulting in respiratory complications including hemoptysis.	25725985
Inflammation, Metabolic Diseases, Chronic Kidney Diseases	Altered Intercellular Communication	Protein calorie malnutrition as well as systemic inflammation and metabolic disorders are common among patients with chronic renal failure undergoing renal replacement therapy (haemodialysis), which contributes to its morbidity and mortality.	25726228
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Assessment of the reliability and consistency of the "malnutrition inflammation score" (MIS) in Mexican adults with chronic kidney disease for diagnosis of protein-energy wasting syndrome (PEW).	25726233
Inflammation, Malnutrition, Anorexia, Cachexia, Chronic Kidney Diseases	Altered Intercellular Communication	The protein-energy wasting syndrome (PEW) is a condition of malnutrition, inflammation, anorexia and wasting of body reserves resulting from inflammatory and non-inflammatory conditions in patients with chronic kidney disease (CKD).One way of assessing PEW, extensively described in the literature, is using the Malnutrition Inflammation Score (MIS).	25726233
Inflammation, Malnutrition, Anorexia, Cachexia, Chronic Kidney Diseases	Altered Intercellular Communication	The protein-energy wasting syndrome (PEW) is a condition of malnutrition, inflammation, anorexia and wasting of body reserves resulting from inflammatory and non-inflammatory conditions in patients with chronic kidney disease (CKD).One way of assessing PEW, extensively described in the literature, is using the Malnutrition Inflammation Score (MIS).	25726233
Inflammation, Rectocolitis, Ulcerative	Altered Intercellular Communication	Ulcerative rectocolitis is characterized by diffuse mucosal inflammation and oxidative stress.	25726244
Refractory anemias, Inflammation, Ischemic stroke	Altered Intercellular Communication	A better control of inflammation by new anti-rheumatic treatments will protect the RA patients of deleterious effects of ischemic stroke.	25726631
Inflammation, Tumor necrosis	Altered Intercellular Communication	There was a significant increase in the activity/content of acute inflammation stage proteins: a1-proteinase inhibitor and C-reactive protein as well as anti-inflammatory interleukin-10 compared to the controls while the activity of other inflammatory molecules (leukocyte elastase, tumor necrosis factor alpha, interleukin-1 receptor antagonist) was not changed.	25726782
Inflammation, Schizophrenia	Altered Intercellular Communication	The results suggest that inflammation does not play a significant role in the remote stages of schizophrenia, in contrast to earlier stages of the disease, and the activity of the pathological process decreased in the late stages.	25726782
Inflammation	Altered Intercellular Communication	Acute and chronic inflammation was present around the salivary gland.	25727303
Inflammation	Altered Intercellular Communication	Not only are instances of symptomatic ectopic salivary glands rare, but this was also the first case detected to be caused by the pathophysiology involving the leakage of secretions from an ectopic salivary gland and associated inflammation.	25727303
Inflammation, Hyperlipidemia	Altered Intercellular Communication	Simvastatin treatment could inhibit inflammation and senescence-associated genes in older patients with hyperlipidemia, suggesting its application in inflammatory and age-related diseases.	25727911
Bacteremia, Inflammation	Altered Intercellular Communication	Lipid mediators of inflammation as novel plasma biomarkers to identify patients with bacteremia.	25727996
Bacteremia, Inflammation	Altered Intercellular Communication	Plasma lipid mediators of inflammation can distinguish bacteremia cases from non-bacteremia controls.	25727996
Inflammation, Apathy, Depression, CTCAE	Altered Intercellular Communication	Low-grade inflammation differentiates between symptoms of apathy and depression in community-dwelling older individuals.	25729001
Inflammation, Apathy, Depression, CTCAE	Altered Intercellular Communication	Systemic low-grade inflammation has repeatedly been associated with depression in old age, but the relationship with apathy is less clear.	25729001
Inflammation, Apathy, Depression, CTCAE	Altered Intercellular Communication	This suggests a differential effect of inflammation on apathy and depression.	25729001
Inflammation, Apathy	Altered Intercellular Communication	In older persons, symptoms of apathy may be a behavioral manifestation of concurrent low-grade inflammation.	25729001
Autoimmune Diseases, Inflammation, polychondritis	Altered Intercellular Communication	Relapsing polychondritis is a rare autoimmune disease characterized by inflammation of cartilaginous tissues.	25729816
Inflammation	Altered Intercellular Communication	Increased inflammation and oxidative stress, as well as decreased secretion of cardiac protective factors, may be associated with the simultaneous onset of HHD and CAD.	25729940
Refractory anemias, Inflammation	Altered Intercellular Communication	Deregulation of the MEFV gene is likely to result in uncontrolled inflammation as observed in RA.	25730039
Inflammation, Bacterial Infections	Altered Intercellular Communication	Visual analogue scale of ear complaints, cavity inflammation, and bacterial infection.	25730446
Delirium, Inflammation, Osteochondritis Dissecans	Altered Intercellular Communication	The mechanism of POCD and delirium has been suggested to be associated with inflammation, but its details are unknown.	25731050
Inflammation, Primary malignant neoplasm, Endometriosis	Altered Intercellular Communication	Excluded cases with other cancer or previous cancer treatment, major abdominal pathology or inflammation, endometriosis.	25731151
Inflammation	Altered Intercellular Communication	After the inflammation improved by abscess drainage, we conducted ileocecal resection and fenestrated the abscess.	25731289
Inflammation, Necrosis	Altered Intercellular Communication	Pathological examination of the surgical specimen revealed autolysis of the superficial layer with progression to necrosis and associated inflammation.	25731411
Secondary malignant neoplasm of lung, Secondary malignant neoplasm of liver, Inflammation, Intrahepatic bile duct	Altered Intercellular Communication	However, after completion of the first course of treatment, the patient experienced exacerbation of the liver metastases, pulmonary metastasis, and inflammation of the intrahepatic bile ducts.	25731545
Inflammation, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	Inflammation is particularly strong in huge hepatocellular carcinoma (HCC).	25731733
Inflammation, Neoplasms	Altered Intercellular Communication	However, histology showed no tumor recurrence, but strong inflammation and foreign-body reaction towards Dermabond.	25731826
Inflammation, Data types - Address, Pathology	Altered Intercellular Communication	In AD mice deficient for TREM2, the CD45(hi)Ly6C(+) macrophages are virtually eliminated, resulting in reduced inflammation and ameliorated amyloid and tau pathologies.	25732305
Inflammation Mediators	Altered Intercellular Communication	NOD1 is an intracellular immune receptor that senses peptidoglycan from Gram-negative bacteria and responds by inducing autophagy and activating NF-kB, leading to inflammation-mediated bacterial clearance; however chronic pathogens can evade NOD1-mediated clearance by altering peptidoglycan structure.	25732381
Inflammation, Malignant Lesion, Primary malignant neoplasm	Altered Intercellular Communication	Infection of Mongolian gerbils with an H. pylori pgdA(-) mutant strain led to significantly decreased levels of inflammation and malignant lesions in the stomach; however, preactivation of NOD1 before bacterial challenge reciprocally suppressed inflammation and cancer in response to wild-type H. pylori.	25732381
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	The stimulus for the increase in inflammation in diabetes is still under investigation; however, reactive oxygen species might be a primary source.	25732517
Hemorrhagic Fever, Crimean, Inappropriate ADH Syndrome	Altered Intercellular Communication	Syndrome of inappropriate antidiuretic hormone associated with Crimean-Congo hemorrhagic fever.	25732889
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Reasons for this high co-prevalence include endothelial dysfunction, inflammation, oxidative and emotional stress associated with AF.	25733318
Inflammation, Endothelial dysfunction, Cardiovascular Diseases	Altered Intercellular Communication	A healthy diet is associated with less endothelial dysfunction and less low-grade inflammation over a 7-year period in adults at risk of cardiovascular disease.	25733469
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Endothelial dysfunction and low-grade inflammation play important roles in CVD.	25733469
Inflammation, Thrombosis, Endothelial dysfunction	Altered Intercellular Communication	These data suggest that the dietary modification of endothelial dysfunction and low-grade inflammation, processes that are important in atherothrombosis, is possible.	25733469
Acquired Immunodeficiency Syndrome, HIV Infections	Altered Intercellular Communication	Conversely, markers of HIV infection, current CD4 or CD8 values, CD4 nadir, CD4/CD8 ratio, AIDS stage at initiation of PIs, current viral load and duration of ART were not associated with immune activation/inflammation markers.	25733587
Inflammation, Anemia	Altered Intercellular Communication	Anemia results from inflammation, preventing iron recycling and decreasing dietary iron absorption.	25733630
Ancylostomatoidea, Inflammation, Schistosoma hematobium infection, Malaria, hepcidin	Altered Intercellular Communication	The objective was to measure inflammation biomarkers, hepcidin, iron absorption, and utilization pre- and posttreatment in children with afebrile malaria, hookworm, and Schistosoma haematobium infection.	25733630
Inflammation, Malaria, hepcidin	Altered Intercellular Communication	Treatment of afebrile malaria reduced inflammation (P < 0.001) and serum hepcidin (P = 0.004) and improved iron absorption (P = 0.003).	25733630
Inflammation, Hookworm Infections, hepcidin	Altered Intercellular Communication	In school-age children, hookworm infection does not produce inflammation or increase serum hepcidin, and it does not influence iron absorption or utilization.	25733630
Inflammation, Malaria	Altered Intercellular Communication	In contrast, afebrile malaria causes inflammation, increases hepcidin, and reduces iron absorption but not utilization.	25733630
HD Term Type, Inflammation	Altered Intercellular Communication	Expressions of proteins for neuroprotection, angiogenesis, and inflammation in the brain tissue of R6/2 HD mice were compared by using immunostaining and Western blotting techniques.	25733809
Neurodegenerative Disorders, HD Term Type, Ototoxicity, Inflammation	Altered Intercellular Communication	We suggest that the herbal formula B401 can be developed as a medical supplement for ameliorating neurodegenerative diseases of HD via reducing mutant huntingtin aggregation and excitotoxicity, enhancing neuroprotection and angiogenesis, and alleviating inflammation in the brain.	25733809
Inflammation, Squamous cell carcinoma	Altered Intercellular Communication	Manuka honey proved a safe, effective, palliative treatment to reduce odor and inflammation in wounds secondary to squamous cell carcinoma of the oral cavity in this patient.	25734464
Inflammation	Altered Intercellular Communication	Kidney-specific accumulation was found in Ga scintigraphy, which suggested chronic inflammation.	25735087
Deficiency of testosterone biosynthesis	Altered Intercellular Communication	Hypoandrogenism is common among infertile men, and routine hormonal evaluation may identify hypoandrogenism in many infertile men with otherwise normal semen analysis.	25735445
Inflammation, Hypertrophy	Altered Intercellular Communication	Chronic inflammation is thought to cause ligamentum flavum (LF) degeneration and hypertrophy in lumbar spinal canal stenosis (LSCS).	25735609
Inflammation, Abnormal degeneration, Hypertrophy	Altered Intercellular Communication	Angptl2 promotes inflammation in LF tissue by activating IL-6 expression, leading to LF degeneration and hypertrophy.	25735609
Inflammation, Obesity	Altered Intercellular Communication	Inflammation but not obesity or insulin resistance is associated with increased plasma fibroblast growth factor 23 concentration in the elderly.	25736796
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Microscopic examination of the lungs following post-mortem examination revealed occlusive granulomatous inflammation of the pulmonary arterial vasculature by crystalline material.	25737334
Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by chronic inflammation.	25738154
Inflammation, Capillaritis	Altered Intercellular Communication	Focal and diffuse peritubular capillaritis (inflammation over 50% of cortical peritubular capillaries) was diagnosed in 10.5 or 14.4% of cases, respectively.	25738252
Inflammation	Altered Intercellular Communication	Inflammation is an important factor in the pathogenesis of FA cardiomyopathy but may be more evident in advanced stages of the disease.	25738292
Inflammatory disease of mucous membrane	Altered Intercellular Communication	A longer disease remission, previous less severe mucosal inflammation, and immunosuppressant use are associated with MH.	25738375
Inflammation, Fever, CTCAE	Altered Intercellular Communication	The predictive value of C-reactive protein and erythrocyte sedimentation rate for 18F-FDG PET/CT outcome in patients with fever and inflammation of unknown origin.	25738560
Inflammation, Fever, CTCAE	Altered Intercellular Communication	In patients with fever of unknown origin or inflammation of unknown origin, compared with elevated ESR levels, elevated CRP levels more often indicate a true positive (18)F-FDG PET/CT outcome.In addition, (18)F-FDG PET/CT, compared with CRP and ESR, shows the highest discrimination of patients with possible disabling disease.	25738560
Brucellosis	Altered Intercellular Communication	Cytokines play a critical role in the regulation of the immune response against brucellosis infection, and mediate production of many pro- and anti-inflammatory signals.	25738611
Inflammation, Neoplasms	Altered Intercellular Communication	The present findings suggest that inflammation may promote angiogenesis and consequently contribute to tumor progression.	25738867
Autistic Disorder	Altered Intercellular Communication	Prediction of autism by translation and immune/inflammation coexpressed genes in toddlers from pediatric community practices.	25739104
Inflammation, Hypertension, CTCAE, Atherosclerosis	Altered Intercellular Communication	T cell-driven inflammation in human hypertension and atherosclerosis has recently been revealed.	25739534
Inflammation, Malignant neoplasm of endometrium	Altered Intercellular Communication	Inflammation may be important in endometrial cancer development.	25739930
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Long-chain o-3 (n-3) polyunsaturated fatty acids (LCo-3PUFAs) may reduce inflammation and, therefore, reduce cancer risk.	25739930
Inflammation, Malignant neoplasm of endometrium	Altered Intercellular Communication	Because body mass is associated with both inflammation and endometrial cancer risk, it may modify the association of fat intake on risk.	25739930
Myocarditis	Altered Intercellular Communication	Five patients had nonischemic late gadolinium enhancement (LGE) lesions within the left ventricular (LV) myocardium, and 3 patients demonstrated CMR evidence of myocardial inflammation.	25740233
Fibrous, Inflammation, Dental Plaque, Coronary heart disease	Altered Intercellular Communication	%CD14 and %CD163 had a significant positive correlation with %NC (%CD14: r = 0.40, P = 0.01 and %CD163: r = 0.45, P = 0.01), but only %CD163 was negatively correlated with %Fibrous (%CD163: r = -0.48, P = 0.01).These findings suggest that the presence of CD14- and CD163-positive macrophages may reflect plaque inflammation, NC expansion, and plaque vulnerability in patients with coronary heart disease.	25740391
Inflammation, Malnutrition	Altered Intercellular Communication	Transthyretin (TTR), a sensitive indicator of malnutrition and inflammation, has been shown to be associated with mortality in elderly population.	25740746
Inflammation	Altered Intercellular Communication	Subclinical low-grade inflammation, elevated serum copper and decreased hemoglobin were associated with decreased serum TTR in community-living elderly Japanese women and may represent important confounders of the relationship between low TTR and mortality in the elderly.	25740746
Inflammation, Hepatitis B	Altered Intercellular Communication	Hepatitis B virus and hepatitis C virus do not cause aggressive activation of an oncogenic pathway, but they transactivate a broad array of genes, cause chronic inflammation, and, through interference with mitotic processes, lead to mitotic error-induced chromosome instability (ME-CIN).	25740822
Colorectal Carcinoma	Altered Intercellular Communication	The metabolism of PUFAs may play an important role in the evolution of inflammation-driven tumorigenesis in CRC and may be considered a potential marker for prognosis.	25741148
Sepsis, Inflammation, Inflammatory disorder	Altered Intercellular Communication	Mean platelet volume (MPV) is suggested as an index of inflammation, disease activity, and anti-inflammatory treatment efficacy in chronic inflammatory disorders; however, the effect of MPV on sepsis mortality remains unclear.	25742300
Inflammation, Glomerulonephritis	Altered Intercellular Communication	Urinary thrombin: a novel marker of glomerular inflammation for the diagnosis of crescentic glomerulonephritis (prospective observational study).	25742509
Inflammation, Glomerulonephritis	Altered Intercellular Communication	Crescentic glomerulonephritis (CresGN), an uncommon rapidly progressive disease, is characterized by severe glomerular inflammation with fibrin deposition.	25742509
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Thrombinuria was specific for glomerular inflammation, was unaffected by systemic inflammation or coagulation, and demonstrated good diagnostic accuracy for CresGN including ANCA-negative cases.	25742509
Inflammation, Gall Bladder Diseases	Altered Intercellular Communication	Gallbladder disease is highly related to inflammation, but the inflammatory processes are not well understood.	25743242
Chorioretinitis, Intraocular inflammation, Inflammation	Altered Intercellular Communication	At initial ocular examination (baseline), 30 patients (9.9%) had intraocular inflammation only (anterior chamber cells and flare, vitreous inflammatory reactions, retinal whitening), without clinically apparent necrotizing retinochoroiditis.	25743338
Alzheimers Disease", vascular inflammations	Altered Intercellular Communication	The amyloid beta peptide is the major protein constituent of neuritic plaques in Alzheimer disease and appears to play a central role in vascular inflammation pathophysiology.	25744007
Autoimmune Diseases, Inflammation, Pericarditis, CTCAE	Altered Intercellular Communication	Pleuritis and pericarditis, inflammation of the pleura and pericardium, may represent manifestations of autoimmune disorders especially in female subjects.	25744068
Allergy - Charge Type Reason	Altered Intercellular Communication	Interleukin 10 (IL-10) is an immunoregulatory cytokine with biological functions of anti-inflammation, immunosuppression, allergy, and anti-agenesis.	25744234
Inflammatory Bowel Diseases	Altered Intercellular Communication	Inflammatory bowel disease is a group of chronic inflammatory conditions affecting gastrointestinal tract.	25744728
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Despite typical POV architecture was preserved, signs of inflammation were found in glaucoma groups.	25744981
Inflammation, Vascular Diseases, Atherosclerosis	Altered Intercellular Communication	Relationship of cigarette smoking with inflammation and subclinical vascular disease: the Multi-Ethnic Study of Atherosclerosis.	25745060
Inflammation, Cardiovascular Diseases, Atherosclerosis	Altered Intercellular Communication	We sought to assess the impact of smoking status, cumulative pack-years, and time since cessation (the latter in former smokers only) on 3 important domains of cardiovascular disease: inflammation, vascular dynamics and function, and subclinical atherosclerosis.	25745060
vascular inflammations, Hypertensive (finding), Damage	Altered Intercellular Communication	The relationship between vascular inflammation and target organ damage in hypertensive crises.	25745795
vascular inflammations	Altered Intercellular Communication	Monocyte chemoattractant protein-1 (MCP-1) is responsible for the recruitment of monocytes to sites of vascular inflammation.	25745795
vascular inflammations, Hypertensive (finding), Terminal Osseous Dysplasia and Pigmentary Defects	Altered Intercellular Communication	According to our results, we suggest that increased vascular inflammation and MCP-1 levels might be associated with the development of TOD in hypertensive crisis.	25745795
NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology, Inflammation, Miller Dieker syndrome, Vasculitis, CTCAE	Altered Intercellular Communication	Paraneoplastic inflammation of the large vessels is a rare complication of myelodysplastic syndrome (MDS), and patients with MDS and systemic vasculitis have a poor prognosis.	25745966
Inflammation	Altered Intercellular Communication	Longitudinal assessment of inflammation in recipients of continuous-flow left ventricular assist devices.	25746024
Inflammation	Altered Intercellular Communication	Despite improvements in LV dimensions and BNP levels, markers of inflammation remained higher in CF-LVAD recipients.	25746024
Inflammation, Heart failure	Altered Intercellular Communication	High levels of inflammation in CF-LVAD recipients may result from heart failure preconditioning or the long-term device support, or both.	25746024
Inflammation	Altered Intercellular Communication	Because inflammation may be detrimental to CF-LVAD recipients, future studies should determine whether inflammatory pathways are reversible.	25746024
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Ceramide is involved in apoptosis, inflammation, and stress responses, which are among the pathogenic components of chronic heart failure (CHF).	25746025
Inflammation, Giant Cell Arteritis	Altered Intercellular Communication	A biopsy of superficial temporal artery showed the characteristic findings of glanulomatous inflammation indicative of giant cell arteritis.	25746074
Inflammation	Altered Intercellular Communication	Magnetic resonance imaging of the brain early in his illness showed focal inflammation in the periaqueductal gray matter and hypothalamus.	25746964
neutrophilic, Asthma, Inflammation	Altered Intercellular Communication	TH17 cells and gd-17 cells, proposed drivers of neutrophilic inflammation, were not strongly associated with asthma, even in severe neutrophilic forms.	25746968
Inflammation, Brain Injuries, Dental Plaque, "Alzheimers Disease	Altered Intercellular Communication	The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease.	25747037
Cessation of life, Inflammation, Necrosis	Altered Intercellular Communication	Receptor-interacting protein kinase-3 (RIP3 or RIPK3) is an essential part of the cellular machinery that executes "programmed", or "regulated", necrosis and has a key role in spontaneous cell death and inflammation in keratinocytes under certain conditions.	25748555
Inflammation, Dyssomnias	Altered Intercellular Communication	Sleep disturbance is associated with activation of systemic and cellular inflammation, as well as proinflammatory transcriptional profiles in circulating leukocytes.	25748580
Inflammation, Sleeplessness	Altered Intercellular Communication	Whether treatments that target insomnia-related complaints might reverse these markers of inflammation in older adults with insomnia is not known.	25748580
Sleeplessness, Inflammation	Altered Intercellular Communication	Among older adults with insomnia, CBT-I reduced systemic inflammation, TCC reduced cellular inflammatory responses, and both treatments reduced expression of genes encoding proinflammatory mediators.	25748580
Sleeplessness, Inflammation, Inflammatory disorder	Altered Intercellular Communication	The findings provide an evidence-based molecular framework to understand the potential salutary effects of insomnia treatment on inflammation, with implications for inflammatory disease risk.	25748580
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	An increased faecal load in the colon with or without delayed transit will increase bacterial counts and create a chronic inflammation of the colonic mucosa, which is a risk factor for cancer onset.	25748875
Breast Carcinoma, Inflammation, Sleeplessness	Altered Intercellular Communication	Tai chi, cellular inflammation, and transcriptome dynamics in breast cancer survivors with insomnia: a randomized controlled trial.	25749595
Inflammation, Hypercapnia	Altered Intercellular Communication	Under intravenous anesthesia, therapeutic hypercapnia inhibits local and systematic inflammation and improves respiratory function after OLV in lobectomy patients without severe complications.	25751232
Structure of lamina episcleralis, Exophthalmos, Orbital Pseudotumor, Carotid-Cavernous Sinus Fistula	Altered Intercellular Communication	A 4-month-old male infant with proptosis and episcleral injection initially thought to have orbital inflammation was found to have an indirect carotid-cavernous sinus fistula.	25751239
Refractory anemias, Inflammation, Damage	Altered Intercellular Communication	Therefore, we aimed to examine the effects of ALA on serum biomarkers of joint damage and inflammation in women with RA.	25751300
Atrophic, Necrosis	Altered Intercellular Communication	Muscle biopsy showed necrotic fibers, focal sparse perivascular inflammation/perifascicular atrophy, endomysial/epimysial vessel wall thickening with luminal narrowing.	25751473
ARCN1 gene, Communicable Diseases, Pneumonitis	Altered Intercellular Communication	Infected mice with experimental COPD also had more severe infection (increased viral titer and pulmonary inflammation, and compromised lung function).	25751541
Inflammation, Vitreous strands	Altered Intercellular Communication	The number of vitreous cells increased significantly in the cases with clinically active inflammation (2297 versus 207 cells/ml, respectively, p < 0.01, Mann-Whitney U-test).	25752226
Vasculitis	Altered Intercellular Communication	However, inhibition of 5-LO with VIA-2291 is not associated with significant reductions in vascular inflammation (by FDG-PET) or in blood inflammatory markers.	25752438
Communicable Diseases, Helicobacter pylori, Inflammation, Peptic Ulcer	Altered Intercellular Communication	The eradication rate of Helicobacter pylori (H. pylori) infection might be affected by the degree of inflammation of gastric mucosa represented by the endoscopic stage of peptic ulcer disease (PUD).	25752487
Inflammation, Observation Method - Coagulation, Prediabetes syndrome, Endothelial dysfunction	Altered Intercellular Communication	Inflammation, coagulation, endothelial dysfunction and oxidative stress in prediabetes--Biomarkers as a possible tool for early disease detection for rural screening.	25753569
Inflammation, Obesity	Altered Intercellular Communication	Interventions targeting obesity might improve sedentary behavior and physical activity, whereas interventions targeting inflammation might improve physical activity in these populations.	25753603
Inflammation	Altered Intercellular Communication	Early life course inflammation and cardiovascular reactivity are important candidate pathways through which the repeated exposure to discrimination for minority group members contributes to racial and economic health inequities in adulthood.	25753652
Inflammation, ABCA4 gene, muscle mass	Altered Intercellular Communication	The decrease in fat free mass (FFM), muscle mass (MM) and increase in visceral fat is associated with an elevated secretion of cytokines which promote systemic inflammation.	25754053
ARCN1 gene, Inflammation	Altered Intercellular Communication	Body compositions abnormality and higher activity of systemic inflammation could therefore be a negative prognostic factor in COPD patients.	25754053
Inflammation, Thyroid associated opthalmopathies	Altered Intercellular Communication	Medics initially thought the presentation was related to an intracranial pathology but through subsequent tests and examination, ophthalmologists diagnosed a severe case of thyroid eye disease with intense inflammation.	25754167
Neoplasms	Altered Intercellular Communication	Macroadenoma can lead to atypical hormonal test results and complete removal of the tumour is unlikely.	25754284
Attention deficit hyperactivity disorder, Mood Disorders, Neurodevelopmental Disorders, Behavior Disorders	Altered Intercellular Communication	Models adjusted for sociodemographic correlates, other physical and mental disorders, and false discovery and revealed broad patterns of associations between neurodevelopmental disorders with behavior disorders (odds ratio [OR]: 1.5; 95% confidence interval [CI]: 1.3-1.8; P < .004) and attention-deficit/hyperactivity disorder (OR: 3.1; 95% CI: 2.7-3.6; P < .0001), and neurologic/central nervous system conditions (OR: 1.3; 95% CI: 1.1-1.9; P < .05) with mood disorders and attention-deficit/hyperactivity disorder (OR: 1.3; 95% CI: 1.1-1.5; P < .001), and autoimmune/inflammatory conditions with mood disorders (OR: 1.4; 95% CI: 1.1-1.8, P < .05).	25755242
Granulomatous inflammation, FGFR1OP gene, Acute infectious disease	Altered Intercellular Communication	With respect to secondary FOP, acute infection and granulomatous inflammation are the main causes.	25755741
Inflammation	Altered Intercellular Communication	Transforming growth factor-beta-induced (TGFBI) serves as a linker protein and plays a role in the activation of morphogenesis, cell proliferation, adhesion, migration, differentiation and inflammation.	25755764
Communicable Diseases, Xanthogranulomatous inflammation	Altered Intercellular Communication	Given that some types of xanthogranulomatous inflammation (XGI) are associated with pathogens, infection should be considered as a possible cause of XGG.	25755811
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	These findings suggest that MIG may be used as a novel biomarker for T-cell inflammation and atherosclerotic plaque burden in humans.	25756330
Cardiac Arrest, Inflammation	Altered Intercellular Communication	The aim was to investigate the association between level of systemic inflammation and mortality in survivors after out-of-hospital cardiac arrest treated with targeted temperature management.	25756419
Inflammation, Carcinogenesis, Malignant Neoplasms	Altered Intercellular Communication	It has been proposed that carcinogenesis is a result of asbestos-induced inflammation but it is not clear what contributes to the differences observed between incidences of these two cancers.	25757056
Gingivitis	Altered Intercellular Communication	Furthermore, there was a significant difference in Modified Gingival Index (MGI, P = 0.02) between the two groups with the study group having less gingival inflammation.	25757137
Inflammation	Altered Intercellular Communication	RAGE is a transmembrane receptor expressed on immune and endothelial cells, whose binding with its ligands, the S100 calgranulins, leads to chronic inflammation.	25757448
Sjogrens Syndrome", Inflammation	Altered Intercellular Communication	MUC1/SEC and MUC1/Y overexpression is associated with inflammation in Sjogren's syndrome.	25757505
Neurodegenerative Disorders, "Alzheimers Disease", Data types - Address, Inflammation	Altered Intercellular Communication	In addition, it has been shown that the pathogenesis of neurodegenerative disorders, such as Alzheimer's disease (AD), involves inflammation as well as oxidative stress.	25758069
Inflammation, Abnormal degeneration, Equilibration disorder	Altered Intercellular Communication	An increased calcium-phosphate product level was suspected as an etiology, although degeneration, inflammation and/or mineral balance disorders may also induce the development of CAT.	25758074
HMGCL gene	Altered Intercellular Communication	A personal prior history of chronic inflammatory condition was not associated with an increased risk of HL (0.94; 0.71-1.14).	25758095
Inflammation, Diabetic Angiopathies	Altered Intercellular Communication	Inflammation and complement activation initiated by mannose-binding lectin (MBL) may be implicated in the pathogenesis of diabetic vascular complications.	25758771
Malnutrition, HD Term Type, Inflammation	Altered Intercellular Communication	It can be concluded that, in addition to old age, malnutrition (low GNRI) and inflammation (high ferritin) are identified as significant independent risk factors that predict all-cause mortality in HD patients.	25758879
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Circulating angiogenic factors (AF) reflect tissue healing capacity, although some AF can also contribute to inflammation and are indicative of endothelial dysfunction.	25759146
Inflammation, Amyloidosis, Familial, Atherosclerosis	Altered Intercellular Communication	In contrast to hereditary amyloidosis, wherein specific mutations of apoA-I cause protein destabilization and amyloid deposition, oxidative conditions similar to those promoted by local inflammation in atherosclerosis are sufficient to transform full-length wild-type apoA-I into an amyloidogenic protein.	25759391
Inflammation, Diabetic foot ulcer	Altered Intercellular Communication	In conclusion, following wound bed preparation for diabetic foot ulcers, MDR bacteria numbers were increased and antibiotic sensitivity was decreased; inflammation was decreased.	25759414
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	HBsAg levels were compared among different liver inflammation grades, as well as different hepatic fibrosis stages.	25759544
Inflammation, Hepatitis B	Altered Intercellular Communication	In hepatitis B e antigen-negative chronic hepatitis B, serum HBsAg levels in liver histological inflammation grades 1-4 were 3.66 +- 0.40, 3.74 +- 0.35, 3.74 +- 0.26 and 3.71 +- 0.34 log10 COI (cut off index), respectively, and there were no differences before apportion (P = 0.640).	25759544
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Serum HBsAg levels apportioned by the same HPCV (hepatic cell quantities), rather than serum HBsAg levels, increase with liver inflammation grades and hepatic fibrosis stages.	25759544
Inflammation, Hemorrhage, Schistosoma japonicum, Necrosis	Altered Intercellular Communication	Histopathological examination revealed mucosal necrosis and hemorrhage with a large number of infiltrating eosinophils and neutrophils, and acute submucosal inflammation with a large number of infiltrating eosinophils and neutrophils associated with Schistosoma japonicum (S. japonicum) eggs.	25759563
Inflammation	Altered Intercellular Communication	An additional 10 (29.4%) specimens contained a combination of acute and chronic inflammation.	25760207
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Recent studies have revealed that cancer cells are exacerbated by chronic inflammation.	25761055
Inflammation, Anemia	Altered Intercellular Communication	The first axis was associated with anemia, inflammation, and low levels of calcium and albumin.	25761112
Fibrosis, Liver, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Red blood cell distribution width levels correlate with liver fibrosis and inflammation: a noninvasive serum marker panel to predict the severity of fibrosis and inflammation in patients with hepatitis B.	25761184
Fibrosis, Liver, Inflammation, Hepatitis B	Altered Intercellular Communication	A total of 446 hepatitis B virus-infected patients who underwent liver biopsy were divided into 2 groups: absent or mild and moderate-severe according to the severity of liver fibrosis and inflammation.	25761184
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The independent variables that determine the severity of liver fibrosis and inflammation were explored.	25761184
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	RDW values increased with progressive liver fibrosis and inflammation.	25761184
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	After adjustments for other potent predictors, liver fibrosis (moderate-severe) was independently associated with RDW, platelet, and albumin (odds ratio = 1.121, 0.987, and 0.941, respectively), whereas increased odds ratios of significant inflammation were found for RDW, alanine aminotransferase, albumin, and PLT (odds ratio = 1.146, 1.003, 0.927, and 0.990, respectively).	25761184
Hepatitis	Altered Intercellular Communication	The sensitivity and specificity of model B were 66.1% and 79.4% for predicting advanced liver inflammation (AUC = 0.765, P < 0.001).	25761184
Renal Insufficiency, Interstitial inflammation	Altered Intercellular Communication	The density of CCL18(+) cells correlated with crescent formation, interstitial inflammation, and impairment of renal function.	25762060
Nephritis	Altered Intercellular Communication	In summary, our data indicate that CCL18 drives renal inflammation through CCR8-expressing cells and could serve as a biomarker for disease activity and renal relapse in ANCA-associated crescentic GN.	25762060
Pain Distress Question, Inflammation	Altered Intercellular Communication	Based on the number of non-invasive methods, to reduce muscle tension, mute pain and alleviation of inflammation.	25763584
Inflammation, Calcification of coronary artery	Altered Intercellular Communication	Association of systemic inflammation with epicardial fat and coronary artery calcification.	25763815
Inflammation	Altered Intercellular Communication	While it is postulated to be an independent risk factor, a possible mechanism is local or systemic inflammation.	25763815
Inflammation, Atherosclerosis	Altered Intercellular Communication	We analyzed the relationship between coronary atherosclerosis, quantified by coronary calcium in CT, epicardial fat volume and systemic inflammation.	25763815
Inflammation, SLC25A20 gene	Altered Intercellular Communication	The progression of CAC was significantly correlated with the extent of EFV (P < 0.001) while there was no significant correlation between progression of EFV or CAC with systemic inflammation markers.	25763815
Inflammation, SLC25A20 gene	Altered Intercellular Communication	While both baseline EFV and CAC displayed significant correlations with systemic inflammation markers, biomarkers were not predictive of the progression of CAC or EFV.	25763815
Pneumonitis, Metapneumovirus	Altered Intercellular Communication	Human metapneumovirus infection activates the TSLP pathway that drives excessive pulmonary inflammation and viral replication in mice.	25763996
Pneumonitis	Altered Intercellular Communication	Here, we evaluated whether the thymic stromal lymphopoietin (TSLP) pathway contributes to lung inflammation upon hMPV infection.	25763996
Pain Distress Question, Inflammation	Altered Intercellular Communication	Those patients had developed symptoms of pain and local knee inflammation six years after total knee replacement.	25764647
palladium, Inflammation, Mesothelial cell	Altered Intercellular Communication	Inflammation cooperates with high GDP PD fluids to promote mesothelial cell death, which is resistant to several therapeutic approaches.	25765663
Inflammation, Metabolic Diseases, Diabetes Mellitus	Altered Intercellular Communication	Diabetes is a serious metabolic disorder and oxidative stress and inflammation contribute to its pathogenesis and complications.	25765835
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Omentin is a member of the adipokines, and has a protective effect against vascular inflammation and pathological remodeling leading to atherosclerosis as well as a vasodilatory effect.	25766303
vascular inflammations	Altered Intercellular Communication	These results suggest that a loss of omentin-dependent protection against vascular inflammation and remodeling may be related to pathological vascular events of early dcSSc.	25766303
Inflammation, Injury of cardiac valve, Myocardial Infarction, Myocardial Stunning, Ischemic	Altered Intercellular Communication	Ischaemic haemodialysis (HD)-induced cardiac injury (myocardial stunning) is common and is associated with markers of myocardial necrosis, inflammation, cardiovascular events and mortality.	25766334
Inflammation	Altered Intercellular Communication	Increased CXCL-1 levels may be indicative of mild inflammation in the detached retina and the adjacent vitreous.	25766782
Inflammation	Altered Intercellular Communication	Additionally, increased inflammation in patients with ERM probably requires more frequent injections.	25768251
Inflammation	Altered Intercellular Communication	Overall, we see a shift in the transcriptome from immunity and inflammation to repair and recovery during the course of a DENV infection.	25768297
Inflammation, Dengue Fever	Altered Intercellular Communication	Time since onset of disease associates with the shift in transcriptome signatures from immunity and inflammation to cell cycle and repair mechanisms in patients with non-severe dengue.	25768297
Communicable Diseases, Inflammation	Altered Intercellular Communication	C-reactive protein (CRP), a marker of infection and inflammation, is produced mainly in the liver.	25769586
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The platelet-to-lymphocyte ratio (PLR) has been proposed as an easily assessable marker of systemic inflammation and has been shown to represent a prognostic marker in different cancer entities.	25769845
Inflammation, Dysautonomia	Altered Intercellular Communication	The pathophysiological mechanisms underlying this association remain poorly understood, although several candidates including inflammation, cardiac autonomic dysregulation, and behavioural factors are viewed as of key importance.	25770081
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Association of serum total bilirubin level with severity of coronary atherosclerosis is linked to systemic inflammation.	25770689
Scleritis	Altered Intercellular Communication	We included a total of 30 eyes of 30 patients with unilateral anterior scleral or episcleral inflammation.	25771347
Inflammation, Chronic multifocal osteomyelitis	Altered Intercellular Communication	Histopathology demonstrated only non-specific chronic inflammation compatible with CRMO.	25771734
Tick-borne encephalitis vaccine, herpesvirus 3, human, Inflammation, Enterovirus meningitis	Altered Intercellular Communication	Ninety-six patients with clinically and laboratory proven tick-borne encephalitis (TBE) and 77 patients with a confirmed diagnosis of enteroviral meningitis (EVM), along with a control group of 107 patients without evidence of inflammation in the CSF were retrospectively tested by nested PCR for the presence of DNA of the neurotropic herpesviruses HSV1, HSV2, VZV, and HHV6 in the CSF.	25771938
Inflammation, glycation, Necrosis	Altered Intercellular Communication	The high motility group box 1 (HMGB1) protein triggers inflammation, cell proliferation and cell survival through its receptor for advanced glycation end products (RAGE) upon release from stressed or necrotic cells.	25772690
Inflammation, Fibrosis Assessment, Biatrial enlargement, Necrosis	Altered Intercellular Communication	In parallel with AF, KO mice developed progressive biatrial enlargement with inflammation, heterogeneous fibrosis, and loss of cardiomyocyte population with apoptosis and necrosis.	25773299
Inflammation, Necrosis	Altered Intercellular Communication	Fibrocartilage exhibited reactive features including increased extracellular myxoid matrix, binucleation, and focal necrosis, without cellular inflammation.	25774101
Inflammation, Metabolic Syndrome X, Microalbuminuria, ETV3 wt Allele, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Odds ratios (ORs) examining the association between intermediate endpoints (metabolic syndrome [MetS], nonalcoholic fatty liver disease [NAFLD], systemic inflammation, and microalbuminuria) and the two metabolic phenotypes were evaluated.	25774664
Microalbuminuria, Inflammation, Non-alcoholic Fatty Liver Disease, ETV3 wt Allele	Altered Intercellular Communication	After multivariable adjustment, compared to the insulin-sensitive group, the insulin-resistant group had higher odds of having MetS (OR, 5.47; 95% confidence interval [CI]: 1.72, 17.35; p=0.004) and NAFLD (OR, 8.66; 95% CI, 2.48, 30.31; p=0.001), but not systemic inflammation (OR, 1.06; 95% CI: 0.56, 2.03; p=0.86) or microalbuminuria (OR, 1.71; 95% CI, 0.49, 6.04; p=0.403).	25774664
Inflammation	Altered Intercellular Communication	Moreover, CTD in patients with cardiovascular involvement was more likely to be complicated by ILD (p < 0.01), which manifested as a higher alveolar inflammation score (p < 0.05).	25775471
Inflammation	Altered Intercellular Communication	Cardiovascular involvement is increased in CTD patients, and is associated with ILD with a higher alveolar inflammation score.	25775471
Inflammation, Data types - Address	Altered Intercellular Communication	Increasing evidence implicates inflammation in AD, the origins of which are not completely understood.	25775543
Inflammation, Data types - Address	Altered Intercellular Communication	We investigated whether circulating Ab could initiate inflammation in AD via the plasma contact activation system.	25775543
Inflammation	Altered Intercellular Communication	These findings suggest that delayed vascular healing and persistent peristent inflammation may be present even at 12 months after Zilver PTX implantation.	25775679
Osteomyelitis, Inflammation, Thrombophlebitis	Altered Intercellular Communication	The inflammation process spreads from sinuses by valveless diploic veins of the skull as thrombophlebitis or by direct extension of osteomyelitis.	25775820
Inflammation, Bacterial Endocarditis	Altered Intercellular Communication	The mechanisms that underlie valvular inflammation in streptococcus-induced infective endocarditis (IE) remain unclear.	25776751
Sepsis, Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Inflammation and coagulation are closely interrelated processes in the pathogenesis of sepsis.	25776897
Inflammation, Diverticulosis	Altered Intercellular Communication	It remains unclear whether diverticulosis, absent inflammation, is responsible for chronic bowel symptoms.	25777157
Inflammation, Neoplasms	Altered Intercellular Communication	An increased peripheral blood neutrophil to lymphocyte ratio (NLR) is a marker of systemic inflammation and is linked to poor prognosis in some solid tumors.	25777682
Inflammation, Bronchiolitis Obliterans, Fibrosis Assessment, Lung Diseases, Obstructive	Altered Intercellular Communication	Bronchiolitis obliterans (BO) was defined as a nonreversible obstructive lung disease in which the bronchioles are always compressed and narrowed by fibrosis or inflammation.	25777978
Inflammation	Altered Intercellular Communication	Tartrate-resistant acid phosphatase 5a (TRACP5a) is proposed to be related to chronic inflammation.	25778334
Refractory anemias, Inflammation, ciliary vesicle	Altered Intercellular Communication	Since inflammation and Endothelial Progenitor Cells (EPCs) imbalance have been reported in RA patients to be related to CV disease, we wondered whether RDW could be linked to endothelial repair failure in RA.	25778627
Pain Distress Question, Inflammation, Exudate, Edema, Bipolar Disorder, Fatigue	Altered Intercellular Communication	The EFA identified two distinct symptom clusters: a 'systemic symptom cluster' consisting of pain, fatigue and depressive symptoms; and a 'localised-leg symptom cluster' including pain, fatigue, oedema, lower limb inflammation and exudate.	25779851
Inflammation	Altered Intercellular Communication	Abrogation of mesenchymal TGFb signalling markedly attenuated bleomycin-induced fibrotic pathology, which was independent of altered early inflammation.	25779936
Chronic Periodontitis, Inflammation	Altered Intercellular Communication	Chronic periodontal diseases involve bacteria-induced inflammation of the tissues supporting the teeth.	25780017
Inflammation, Hypertension, CTCAE, Dental Plaque	Altered Intercellular Communication	Hypertension was also associated with high level of dental plaque [OR = 1.90, 95% CI = 1.55-2.33], dental calculus [OR = 1.18, 95% CI = 1.07-1.29] and gingival inflammation [OR = 1.56, 95% CI = 1.35-1.80] Moreover, in this subset <65 years, the risk of hypertension increases with the number of dental exposure.	25780017
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	The present study indicates that insufficient masticatory function, poor oral hygiene, and oral inflammation are associated with hypertension in subject <65.	25780017
Inflammation, Crohn Disease	Altered Intercellular Communication	Fecal calprotectin (fCal) is widely used as marker of gut inflammation and is strongly associated with the severity of endoscopic lesions in Crohn's disease (CD).	25781366
Increased insulin level, Endocrine System Diseases, Hypothyroidism, Diabetes Mellitus	Altered Intercellular Communication	They may be associated with endocrine disorders, including hypothyroidism, diabetes mellitus, hyperinsulinemia and growth hormone (GH) deficiency.	25781523
Narrow Band Imaging, Granulomatosis, Autoimmune Diseases, Granulomatosis with polyangiitis, vascular inflammations, Systemic Vasculitis	Altered Intercellular Communication	Because granulomatosis with polyangiitis (GPA) (Wegener granulomatosis) is an autoimmune disease defined by vascular inflammation, we examined patients with GPA and with NBI to evaluate whether disease-specific mucosal vascular patterns were present.	25781561
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Variants at the interleukin 6 receptor (IL6R) gene regulate inflammation and are associated with risk of coronary heart disease (CHD).	25781951
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Amplified inflammation persists in the airways of patients with chronic obstructive pulmonary disease (COPD); however, the underlying mechanism is still unclear.	25782336
Abnormal inflammatory response	Altered Intercellular Communication	Th17/T regulatory cells (Treg) imbalance may exist in the airways and contribute to this abnormal inflammation.	25782336
Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	Inflammation in the aging brain increases risk for neurodegenerative disease.	25784210
Herpes Simplex Infections, Inflammation, primary infection nos, Traumatic injury	Altered Intercellular Communication	Herpes simplex virus (HSV) primary infection and reactivation has been associated with the inflammation and transient decrease in immunocompetence after surgery and local trauma.	25785383
Inflammation	Altered Intercellular Communication	To further improve the clinical signs and symptoms and decrease chronic inflammation, rebamipide was added to diquafosol.	25785527
Inflammation, Metaplasia, Squamous metaplasia	Altered Intercellular Communication	Nasal cytology analysis demonstrated a higher percentage of neutrophilic inflammation and squamous cell metaplasia and mucous cell metaplasia in treated patients (p < 0.05).	25785741
Crohn Disease, Inflammation	Altered Intercellular Communication	Crohn's disease-related inflammation is characterized by reduced activity of the immunosuppressive cytokine transforming growth factor b1 (TGF-b1) due to high levels of SMAD7, an inhibitor of TGF-b1 signaling.	25785968
Malignant Neoplasms, Colitis	Altered Intercellular Communication	Elective colonoscopy was considered in cases in which typical colonic wall thickening was observed on CT, suggesting colonic inflammation or malignancy (239 patients; 27%).	25786443
Histiocytosis, Langerhans-Cell, Inflammation	Altered Intercellular Communication	Rather than coincidence, we hypothesize that agminated flexural melanocytic nevi are a late sequela of LCH, possibly resulting from immune tolerance or a reaction to local inflammation.	25787131
vascular inflammations, Dental Plaque	Altered Intercellular Communication	Placental growth factor (PlGF) contributes to atherogenesis through vascular inflammation and plaque destabilization.	25788536
Inflammatory abnormality of the eye	Altered Intercellular Communication	Inclusion criteria were positive syphilis serology, ocular inflammation on clinical examination and appropriate syphilis treatment.	25788666
Inflammation, HIV Coinfection	Altered Intercellular Communication	Rates of HIV coinfection were high, with patients exhibiting both anterior and posterior segment inflammation.	25788666
allergic inflammation, Gastrointestinal Diseases	Altered Intercellular Communication	Eosinophilic disorders of the gastrointestinal tract are an emerging subset of immune pathologies within the spectrum of allergic inflammation.	25789989
Sjogrens Syndrome", GYPB gene, Autoimmune Diseases	Altered Intercellular Communication	Sjogren's syndrome (SS) is a rheumatic autoimmune disease characterized by inflammation of exocrine glands.	25790192
Sepsis, Inflammation	Altered Intercellular Communication	Clinical manifestations of sepsis are not caused directly by the invading pathogens, but rather mostly by systemic inflammation that leads to activation of the coagulation system.	25790536
Inflammation, Bacterial Infections	Altered Intercellular Communication	The occurrence of a bacterial infection during anti-viral treatment was defined as the onset of local or systemic inflammation as a result of pathogenic bacteria.	25790806
Macular Edema, Cystoid, Inflammation	Altered Intercellular Communication	Intravitreal dexamethasone implant for cystoid macular edema and inflammation after scleral buckling.	25790811
Irvine-Gass Syndrome, Inflammation	Altered Intercellular Communication	Inflammation may be the major causative factor in the development of postoperative cystoid macular edema.	25790811
Retinal Detachment, Macular Edema, Cystoid, Choroiditis	Altered Intercellular Communication	A 59-year-old phakic woman treated with scleral buckling for macula-off retinal detachment presented 2 months after surgery with cystoid macular edema with choroidal inflammation.	25790811
Macular Edema, Cystoid, Choroiditis, Edema	Altered Intercellular Communication	Cystoid macular edema and choroidal inflammation are difficult to treat, but the improvement observed in this case of post scleral buckling macular edema and choroidal inflammation showed how a dexamethasone implant proved to be useful during the 6-month follow-up.	25790811
Inflammation	Altered Intercellular Communication	Response of biomarkers of inflammation and coagulation to short-term changes in central site, local, and predicted particle number concentrations.	25791025
Inflammation	Altered Intercellular Communication	Only central site PNC increased blood markers of inflammation while near-highway and predicted residential values did not.	25791025
Inflammation, Exacerbation	Altered Intercellular Communication	These data together suggest a potential role for this MAPK in Th2 inflammation and possibly during COPD exacerbations.	25791156
Inflammation, Alkalosis	Altered Intercellular Communication	The use of CD is safe and effective in OL-HDF, and it improves dialysis efficacy, postdialysis alkalosis, and inflammation.	25791278
Hepatitis	Altered Intercellular Communication	Invariant natural killer T cell deficiency leads to the development of spontaneous liver inflammation dependent on gdT cells in mice.	25791517
Hepatitis	Altered Intercellular Communication	We measured liver inflammation and the cytokine profiles of liver mononuclear cells in BALB/c wild-type (WT) mice and BALB/c Ja18-deficient (KO) mice lacking iNKT cells.	25791517
Hepatitis	Altered Intercellular Communication	Spontaneous liver inflammation, hepatocyte damage, and anti-nuclear-antibody production occurred in Ja18 KO mice but not in WT mice.	25791517
Hepatitis	Altered Intercellular Communication	In Ja18 KO mice, the administration of anti-gdT-cell-receptor antibody abolished liver inflammation, hepatocyte damage, and IL-17 production.	25791517
Inflammation, Autonomic nervous system disorders	Altered Intercellular Communication	Our findings suggest a joint effect of IR and inflammation on cardiac autonomic dysfunction.	25791914
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	The rates of growth of medically treated abdominal aortic aneurysms (AAA) are difficult to determine, and relationships with parietal inflammation and with metabolic parameters from (18)F-FDG PET remain unclear.	25791991
Gastrointestinal Diseases, Hepatitis, Neuropathy, Colitis, Hypophysitis, CTCAE, Diarrhea, Hypothyroidism, Dermatitis	Altered Intercellular Communication	These specific AEs include dermatitis, gastrointestinal disorders (diarrhea, colitis), hepatitis, hypophysitis, hypothyroidism, neuropathy, and iritis/inflammation of the ciliary body.	25792081
Respiratory Hypersensitivity, AHR wt Allele, Airway structure	Altered Intercellular Communication	There is increasing interest in the role of indirect bronchial challenges because clinical studies have shown that indirect airway hyperresponsiveness (AHR) reflects underlying airway inflammation better than direct AHR.	25792296
Airway structure	Altered Intercellular Communication	Fractional exhaled nitric oxide (FeNO) appears to be a useful clinical tool for assessing airway inflammation noninvasively.	25792296
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Unhealthy lifestyle may increase later depression via inflammation in older women but not men.	25795094
Inflammation, Bipolar Disorder	Altered Intercellular Communication	The findings raise the possibility that unhealthy lifestyle and psychosocial stress may drive inflammation and subsequent depressive symptoms.	25795094
Inflammation, Atherosclerosis	Altered Intercellular Communication	The presence of proinflammatory monocytes/macrophages (CD14+CD16+) has been documented in conditions of inflammation, such as atherosclerosis.	25795161
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP) is increasingly measured as a marker of systemic inflammation that predicts elevated risk for cardiovascular disease.	25795257
Inflammation, Hypercholesterolemia, Endothelial dysfunction	Altered Intercellular Communication	Cowpea protein reduces LDL-cholesterol and apolipoprotein B concentrations, but does not improve biomarkers of inflammation or endothelial dysfunction in adults with moderate hypercholesterolemia.	25795948
Inflammation, Data types - Address	Altered Intercellular Communication	Increasing evidence indicates that inflammation in the brain is a powerful factor in AD progression.	25796175
Inflammation	Altered Intercellular Communication	HF is an acute stress that triggers a state of inflammation which may affect immune responses and physical recovery.	25797136
Inflammation, Opportunistic Infections	Altered Intercellular Communication	Our data showed that the stress caused by HF negatively affects initial PMN responses shortly after the event and that may negatively influence clinical outcomes such as resolving long-term inflammation and recovery, as well as explaining susceptibility to opportunistic infections.	25797136
ARCN1 gene, Inflammation, Cardiovascular system	Altered Intercellular Communication	Evaluation of Markers of Inflammation and Oxidative Stress in COPD Patients with or without Cardiovascular Comorbidities.	25797323
ARCN1 gene, Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Although both chronic obstructive pulmonary disease (COPD) and cardiovascular diseases (CVD) are characterised by chronic, systemic inflammation, their reciprocal interactions are poorly understood.	25797323
ARCN1 gene, Inflammation	Altered Intercellular Communication	Although systemic inflammation coexists with COPD, it is not elevated in COPD patients with CVD.	25797323
Primary malignant neoplasm, Demographics Domain, Myositis, Symptoms, Abnormal pectoral muscle morphology	Altered Intercellular Communication	Also, muscle inflammation can precede the clinical muscle symptoms, and paraneoplastic DM should be considered as a possible differential diagnosis in the assessment of cancer patients who present with abnormal muscle tracer uptake in PET-CT scans.	25797574
Inflammation, Neoplasms	Altered Intercellular Communication	Tumor development and inflammation were determined by endoscopy.	25797700
Inflammation, Waldenstrom Macroglobulinemia, physiopathological	Altered Intercellular Communication	IgG4 related diseases (IgG4-RD) are characterized mainly by organic dysfunction and inflammation with lymphoplasmacytic cells infiltration.	25797707
Inflammation, Atherosclerosis	Altered Intercellular Communication	These findings may provide insight into the role of HCMV in the pathogenesis of atherosclerosis and chronic inflammation in elderly individuals.	25797894
Inflammation	Altered Intercellular Communication	Inadequate separation of vessel and nerve or adhesive inflammation surrounding the nerve root may cause recurrence.	25798798
Refractory anemias, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	This study suggests that inflammation induced by the IL-33/ST2 axis may play a significant role in the development of cardiovascular disease in RA.	25798875
Inflammation, Cushing Syndrome, Dyslipidemias	Altered Intercellular Communication	Dyslipidemia and chronic inflammation markers are correlated with telomere length shortening in Cushing's syndrome.	25799396
Inflammation	Altered Intercellular Communication	Telomere length (TL) shortening is a novel CVR marker, associated with inflammation biomarkers.	25799396
Inflammation, Hypertension, CTCAE, Obesity	Altered Intercellular Communication	TL is shortened in dyslipidemic CS patients, further worse if hypertension and/or obesity coexist and is negatively correlated with increased inflammation markers.	25799396
Inflammation	Altered Intercellular Communication	Increased lipids and a "low" grade inflammation may contribute to TL shortening and consequently to premature ageing and increased morbidity in CS.	25799396
Neurotransmitters, physiopathological	Altered Intercellular Communication	Olfactory dysfunction and neurotransmitter disturbance in olfactory bulb of transgenic mice expressing human A53T mutant a-synuclein.	25799501
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The presence of chronic inflammation in young adults with AP may cause early endothelial dysfunction documented by the reduced EFR.	25799534
Chronic Bacterial Prostatitis, Inflammation, Sexual Dysfunction	Altered Intercellular Communication	An open, prospective, comparative, randomized, placebo-controlled study on the evaluation of the efficacy and safety of combined drug prolit super in patients with chronic abacterial prostatitis without signs of inflammation (NIH 3B category), complicated by sexual dysfunction, was performed.	25799722
Chronic Bacterial Prostatitis, Inflammation, Sexual Dysfunction	Altered Intercellular Communication	The results of the study allows to recommend the appointment of prolit super.in routine clinical practice for patients with chronic abacterial prostatitis without signs of inflammation, complicated by sexual dysfunction.	25799722
Granulomatous inflammation	Altered Intercellular Communication	Out of 28 (59.57%) cases with positive yield 21 (44.68%) were found to have granulomatous inflammation and 10 (21.28%) cases were malignant.	25799803
Pituitary Gland, physiopathological, Congenital Abnormality	Altered Intercellular Communication	Most pituitary lesions are detected during the investigation of symptoms associated with hormonal dysfunction and vision abnormalities.	25800168
Pituitary Diseases, physiopathological	Altered Intercellular Communication	Hormonal dysfunction is quite prevalent, including symptomatic presentations, which suggests that there seems to be a low sensitivity for the diagnosis of pituitary disease.	25800168
Vasculitis	Altered Intercellular Communication	A significant increase of microbiological investigations, imaging techniques and blood inflammation markers were noted after consulting the ID specialist.	25800800
Inflammation, Chronic ulcer, Ulcer, Fracture, Damage	Altered Intercellular Communication	Magnetic resonance imaging, computed tomography as well as bone scintigraphy showed fractures of the right back rib adjacent to the ulcer, which was thought to be attributable to bone damage due to X-ray radiation and/or persistent secondary inflammation of the chronic ulcer.	25800815
Inflammation, Asthma, Psoriasis	Altered Intercellular Communication	Psoriasis and asthma are disorders driven by inflammation.	25801416
Inflammation, Obesity	Altered Intercellular Communication	Obesity has been associated with both changes in adipose tissue lipid metabolism and inflammation.	25801691
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Gamma-delta T lymphocytes and 25-hydroxy vitamin D levels as key factors in autoimmunity and inflammation: the case of zoledronic acid-induced acute phase reaction.	25801887
Autoimmune Diseases, Inflammation, Osteoporosis	Altered Intercellular Communication	Zoledronic acid (ZA) infusion for osteoporosis is frequently associated with the onset of an acute phase reaction (APR) secondary to the activation of gd T cell receptor (TCR) lymphocytes (gd T cells) and to low vitamin D levels, similar to what is observed in chronic inflammation and autoimmunity.	25801887
Inflammation, Miller Dieker syndrome	Altered Intercellular Communication	The present study provides genetic evidence that inflammation and immune dysregulation responses that involve the interferon signaling pathway in the BM microenvironment are associated with MDS pathogenesis, which suggests BM MSCs as a possible therapeutic target in MDS.	25803272
Localized scleroderma, Inflammation	Altered Intercellular Communication	We report a previously well 7-year-old Chinese girl presenting with early facial morphea mimicking an acquired PWS with unusual histologic features of perineural inflammation.	25803570
Localized scleroderma, Inflammation, Inflammatory	Altered Intercellular Communication	The presence of cutaneous perineural inflammation may be seen in a small percentage of cases of morphea and appears to be a feature of early inflammatory morphea.	25803570
Inflammation, Weight decreased	Altered Intercellular Communication	In vivo, however, the virulence and replicative capacity of the different HMPV strains did not appear to be solely dependent on the F gene but also on the viral background, with the strains containing the C-85473 background inducing more weight loss as well as increased lung viral titers, pro-inflammatory cytokines and inflammation than strains containing the CAN98-75 background.	25803584
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Although it is clear that chronic inflammation is a risk factor for colorectal cancer, the details remain uncertain.	25804623
Pancreatic Trypsin Secretory Inhibitor, Kazal, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	Evidence suggests that SPINK1 is an important growth factor that connects chronic inflammation and cancer.	25804623
Grisels syndrome	Altered Intercellular Communication	Grisel's syndrome, an inflammation-mediated atlanto-axial instability occurs rarely in children after adenoidectomy.	25805067
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	The levels of SAMSN1 mRNA in noncancerous liver were not affected by background liver inflammation or fibrosis.	25805236
Myopia, Duane Retraction Syndrome, Cataract	Altered Intercellular Communication	High myopia has long been recognized as an inflammation-related disease, and high myopic eyes are thought to have a proinflammatory internal microenvironment, which might predispose to the occurrence of certain inflammation-related complications such as fibrotic capsular contraction syndrome after cataract surgery.	25805322
Aneurysmal, Inflammation, Necrosis	Altered Intercellular Communication	The aneurysmal wall following clipping showed granulomatous inflammation with necrosis, and occluded aneurysmal walls were found with collagenous fibrous tissue.	25805535
Sarcoidosis	Altered Intercellular Communication	Sarcoidosis is a multisystem chronic inflammatory condition of unknown etiology that has the potential to involve every tissue in the body.	25805948
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	We therefore sought to investigate the associations of inflammation, endothelial dysfunction and cardiovascular risk factors with platelet activation and monocyte-platelet aggregate (MPA) formation in 330 patients undergoing angioplasty with stent implantation for atherosclerotic cardiovascular disease.	25807315
Inflammation, Musculoskeletal Pain	Altered Intercellular Communication	Polymyalgia rheumatica: inflammation suppression with low dose of methylprednisolone or modified-release prednisone.	25807425
Metabolic Diseases, Urinary Calculi	Altered Intercellular Communication	[Hormonal and metabolic disorders as systemic factor for the formation of urinary calculi].	25807757
vascular inflammations, Psoriasis	Altered Intercellular Communication	Subclinical systemic and vascular inflammation detected by (18) F-fluorodeoxyglucose positron emission tomography/computed tomography in patients with mild psoriasis.	25807844
Psoriasis, Arteritis	Altered Intercellular Communication	The association between psoriasis and arterial inflammation, however, has been noted mostly in patients with moderate to severe psoriasis.	25807844
Inflammation, Psoriasis, Cardiovascular Diseases	Altered Intercellular Communication	Therefore, it is still not clear whether mild psoriasis also increases the arterial inflammation and cardiovascular disease.	25807844
Inflammation, Psoriasis	Altered Intercellular Communication	The "candy cane sign", which represents typical arterial inflammation of the thoracic aorta, was noted upon PET in the majority of psoriasis cases.	25807844
Psoriasis, Arteritis	Altered Intercellular Communication	In conclusion, mild psoriasis is also associated with arterial and hepatic inflammation, which can be readily demonstrated by using FDG-PET/CT.	25807844
Secondary malignant neoplasm of liver	Altered Intercellular Communication	Prognostic performance of inflammation-based prognostic indices in patients with resectable colorectal liver metastases.	25807934
Nevus, Inflammation, Lichen Sclerosus et Atrophicus	Altered Intercellular Communication	Histopathologic and immunohistochemical examination performed after topical treatment, showed a compound melanocytic naevus with an underlying inflammation consistent with lichen sclerosus.	25808039
Inflammation, MS gene	Altered Intercellular Communication	Cerebrospinal fluid markers reveal intrathecal inflammation in progressive multiple sclerosis.	25808056
Inflammation, Immune System Diseases	Altered Intercellular Communication	The management of complex patients with neuroimmunological diseases is hindered by an inability to reliably measure intrathecal inflammation.	25808056
Inflammation, Immune System Diseases	Altered Intercellular Communication	The cell-specific biomarkers of intrathecal inflammation may improve diagnosis and management of neuroimmunological diseases and provide pharmacodynamic markers for future therapeutic developments in patients with intrathecal inflammation that is not captured by imaging, such as in progressive MS.	25808056
Inflammation	Altered Intercellular Communication	Such cement remnants may favor the development of inflammation in the peri-implant tissue.	25808842
Inflammation, Neoplasms	Altered Intercellular Communication	UBC with HER2 amplification presented with a broad variety of histological variants (median 2 vs. 1), frequently featured micropapillary tumor components (77 % vs. 8 %) and demonstrated a high amount of tumor associated inflammation.	25809292
Eosinophilic esophagitis, "Extra-osseous Ewings sarcoma	Altered Intercellular Communication	Eosinophilic esophagitis (EoE) is an antigen/allergy-mediated chronic inflammatory condition.	25809945
CLU protein, human, Ischemia, Inflammation, Communicable Diseases	Altered Intercellular Communication	Hemodialysis (HD) patients with critical limb ischemia (CLI) suffer chronic inflammation and repeated infection, require intervention, and may have a protracted hospital stay.	25810351
Inflammation	Altered Intercellular Communication	In HIV+ only, higher adiponectin and IL-6 were associated with worse NP test scores, supporting a role for chronic inflammation and adipocytokine imbalance in neurocognitive decline in HIV+ persons.	25810377
Sepsis, Inflammation, Critical Illness, Bacterial Infections	Altered Intercellular Communication	Strikingly, no differences in miR-223 levels were found in critically ill patients with or without sepsis, and serum levels of miR-223 did not correlate with classical markers of inflammation or bacterial infection.	25810564
Inflammation, Obesity	Altered Intercellular Communication	Associations of fibroblast growth factor-23 with markers of inflammation, insulin resistance and obesity in adults.	25811862
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Prior studies have shown that FGF23 concentrations are associated with markers of inflammation and insulin resistance but they have been limited by a focus on persons with chronic kidney disease (CKD) and lack of race and sex diversity.	25811862
Vascular lesions, Inflammation, Neoplasms	Altered Intercellular Communication	The sensitivity and specificity of CT extravasation and nonvascular findings for predicting vascular lesions and inflammation or tumors were 37.8 and 88.9 and 81.3 and 80.9%, respectively.	25812518
Inflammation, Neoplasms	Altered Intercellular Communication	Contrast-enhanced CT in acute LGIB settings was safe and correctly identified the presence and location of active bleeding, as well as severe inflammation or tumor stenosis, facilitating decision making.	25812518
Autoimmune Diseases, Thrombus, Antiphospholipid Antibodies	Altered Intercellular Communication	Antiphospholipid antibodies (aPL) are heterogeneous group of antibodies found in patients with autoimmune diseases and inflammatory conditions and are associated with thrombotic events.	25812700
Inflammation, Cerebral Aneurysm, Rupture	Altered Intercellular Communication	A growing body of evidence suggests that inflammation actively participates in cerebral aneurysm initiation, progression, and rupture.	25813065
Dermatitis, Atopic, Inflammation, Data types - Address, Allergy - Charge Type Reason	Altered Intercellular Communication	Atopic dermatitis (AD) is a chronic inflammation of the skin recognised to be one of the first clinical signs of allergy.	25813073
Anxiety, CTCAE 3.0, Inflammation	Altered Intercellular Communication	Recent evidence has suggested that anxiety has a genetic basis and is associated with inflammation.	25813148
Gall Bladder Diseases, Postoperative Complications, Actual blood loss, Acute inflammation, Acute Cholecystitis	Altered Intercellular Communication	These findings suggest that when compared to SILC for gallbladder diseases without acute inflammation, SILC for acute cholecystitis was associated with a longer operative time, increased blood loss, higher rate of additional trocar requirement, higher rate of postoperative complications, and longer hospital stay.	25813307
Inflammation, Acute Cholecystitis	Altered Intercellular Communication	The difficulties associated with SILC for acute cholecystitis were affected by the timing of surgery and the grade of inflammation.	25813307
Inflammatory abnormality of the eye	Altered Intercellular Communication	Systemic ATT led to significant improvement and resolution of the ocular inflammation.	25813375
Inflammation, Chronic disease, Obesity	Altered Intercellular Communication	Obesity, defined by an excess amount of body fat or a percent body fat higher than 30 % for women is a complex chronic disorder with multifactorial etiology and is accompanied by chronic low-grade inflammation, which results in elevated pro-inflammatory cytokines.	25813986
Inflammation	Altered Intercellular Communication	The presence of MSC in EMB, cardiac inflammation, and SDF-1a mRNA expression were detected via immunohistochemistry and real-time PCR.	25814787
Inflammation	Altered Intercellular Communication	There was a 29.9% (P < 0.01) transcardiac reduction of circulating MSC in patients with CMi, correlating with the extent of cardiac inflammation (P < 0.05, multivariate analysis).	25814787
Inflammation	Altered Intercellular Communication	Endogenous MSC continuously migrate to the heart in patients with CMi triggered by cardiac inflammation.	25814787
Hepatitis	Altered Intercellular Communication	The frequency of M-MDSCs, however, had no correlation with HCV RNA loads, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and the level of liver inflammation degree.	25815313
Retinitis, Diabetes Mellitus	Altered Intercellular Communication	MicroRNA-146b-3p regulates retinal inflammation by suppressing adenosine deaminase-2 in diabetes.	25815338
Diabetic Retinopathy, Retinitis, GDC Disease Response Terminology	Altered Intercellular Communication	Hyperglycemia- (HG-) Amadori-glycated albumin- (AGA-) induced activation of microglia and monocytes and their adherence to retinal vascular endothelial cells contribute to retinal inflammation leading to diabetic retinopathy (DR).	25815338
Diabetes Mellitus	Altered Intercellular Communication	However, because ADA2 gene has not been identified in mouse genome, how diabetes alters adenosine-dependent anti-inflammation remains unclear.	25815338
Retinitis, Diabetes Mellitus	Altered Intercellular Communication	These results suggest a regulatory role of miR-146b-3p in diabetes related retinal inflammation by suppressing ADA2.	25815338
Inflammation, Electrocardiogram: myocardial infarction (finding), Atherosclerosis	Altered Intercellular Communication	Inflammation and genetics have key roles in the pathogenesis of atherosclerosis, and the etiology of myocardial infarction (MI).	25815703
Inflammation	Altered Intercellular Communication	Examination of the right eye showed vitreous cells, suggesting inflammation of the central retinal vein leading to a CRVO as the presumed mechanism.	25815857
Inflammation, Chronic disease	Altered Intercellular Communication	The overall burden of chronic disease, inflammation and cardiovascular risk increases with age.	25815855
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	A composite z-score for systemic inflammation increased significantly with age in subjects without metabolic syndrome (P=0.004 and P<0.006 for Caucasians and African Americans, respectively) but not in subjects with metabolic syndrome (P=0.009 for difference in age trend between metabolic syndrome and non-metabolic syndrome).	25815855
vascular inflammations	Altered Intercellular Communication	In contrast, no similar age trend was found in vascular inflammation.	25815855
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Our results underscore that already at a young age, presence of a metabolic burden enhances inflammation to a level that appears to be similar to that of decades older people without metabolic syndrome.	25815855
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	In this study we evaluated whether annual exposure to ambient air pollution is associated with systemic inflammation, which is hypothesized to be an intermediate step to cardiovascular disease.	25816055
Inflammation, Dysbiosis	Altered Intercellular Communication	could be evaluated as a dysbiotic reaction, and the presence of opportunistic microflora against the background of high IFNg content with CI of above 10 c.u.--as a development of systemic inflammation due to translocation of dysbiotic microflora into the bloodflow.	25816517
Helicobacter pylori	Altered Intercellular Communication	Thus, in patients with H. pylori inflammation was noted mainly in the antral mucosa and dystrophic changes--in the duodenal mucosa.	25816643
Inflammation	Altered Intercellular Communication	In the presence of viruses the inflammation was expressed more in the fundal stomach and duodenum.	25816643
Hypernatremia	Altered Intercellular Communication	NT-proBNP is a cardiac neurohormone secreted from the ventricles in response to ventricular volume expansion and pressure overload and may also be elevated in the setting of reduced myocardial perfusion.	25816778
Inflammation, Atherosclerosis	Altered Intercellular Communication	Iron, inflammation and atherosclerosis risk in men vs. perimenopausal women.	25817132
Inflammation, Atherosclerosis	Altered Intercellular Communication	Iron homeostasis and inflammation in the arterial wall microenvironment warrants further investigation as a potential early target for interventions that mitigate atherosclerosis risk.	25817132
Inflammation	Altered Intercellular Communication	Activated factor X (FXa) plays a key role in the coagulation cascade, whereas accumulating evidence suggests that it also contributes to the pathophysiology of chronic inflammation on the vasculature.	25817329
Communicable Diseases, Inflammation, Dryness of eye	Altered Intercellular Communication	In conclusion, changes in TLR expression occur in dry eye and could have an important role in ocular surface susceptibility to inflammation and infection.	25817729
Inflammation, Neoplasms	Altered Intercellular Communication	Systemic inflammation and immune response play a crucial role in tumor growth, and the neutrophil to lymphocyte ratio (NLR) may be a simple way to assess the host inflammatory response.	25818659
Inflammation, Rheumatic Heart Disease	Altered Intercellular Communication	The pathogenesis of LA calcification in patients with rheumatic heart disease is unknown; however, possible mechanisms include chronic strain force in the atrial wall and inflammation.	25819539
Asthma	Altered Intercellular Communication	Inflammatory phenotype classification using induced sputum appears attractive as it can be applied to inflammation-based management of the patients with asthma.	25821354
Inflammation	Altered Intercellular Communication	Our findings indicate that oxidative stress is a potential therapeutic target, as it promotes inflammation by ROS/RNS-linked pathogenesis.	25821554
Inflammation, Hand	Altered Intercellular Communication	HIV-induced systemic and localized inflammation is considered to be one of the mechanisms of HAND.	25821806
Addison Disease, Hypogonadism	Altered Intercellular Communication	Hormonal profiling variously showed a normal gonadotrope-testicular axis, gonadotropin deficiency, or primary testicular insufficiency.	25822101
Granulomatosis, Inflammation, Systemic Vasculitis	Altered Intercellular Communication	In particular, differential diagnosis from secondary chronic inflammation including granulomatosis with polyangiitis (GPA) is difficult in some cases.	25822111
Airway structure	Altered Intercellular Communication	Hs-CRP may be useful in monitoring airway inflammation resolution and improvement of health status during AECOPD treatment.	25822151
Airway structure, Inflammation, Fibrosis Assessment, Bronchiectasis	Altered Intercellular Communication	Non-cystic fibrosis (CF) bronchiectasis is characterised by chronic airway infection and neutrophilic inflammation, which we hypothesised would be associated with Th17 pathway activation.	25822228
Renal Insufficiency, Inflammation, Hypoxia, Heart failure	Altered Intercellular Communication	We hypothesized that the frequency of GT(n) repeats in pediatric heart failure (HF) reflects plasma biomarkers of different disease processes: the soluble receptor for advance glycation end products (sRAGE, marking cellular activation), oxLDL (oxidative stress), NGAL (impaired renal function), HIF-1a (hypoxia) and hsCRP (inflammation).	25822459
Inflammation, Pain Distress Question	Altered Intercellular Communication	The participants had radiographic confirmation of clinical OA of the knee, clinical signs of localized inflammation in the knee, and knee pain during walking (score >4 on a scale of 0 to 10).	25822572
Inflammation, Primary malignant neoplasm, Malignant neoplasm of stomach	Altered Intercellular Communication	This retrospective study examines the association of preneoplastic conditions and inflammation of the gastric mucosa with GOJ cancer at different locations and compares them with nonjunctional gastric cancers.	25822856
Intestinal metaplasia, Inflammation, Stomach Carcinoma, Gland	Altered Intercellular Communication	A total of 520 patients with junctional and nonjunctional gastric cancer were assessed for the presence and degree of intestinal metaplasia, glandular atrophy and inflammation in the stomach.	25822856
Intestinal metaplasia, Gastritis	Altered Intercellular Communication	Gastric inflammation and preneoplastic conditions were scored according to the updated Sydney classification and further stratified into respective operative link on gastritis assessment (OLGA) and operative link on gastritis assessment on intestinal metaplasia (OLGIM) stages.	25822856
Meningitis	Altered Intercellular Communication	It has been suggested that this may be due to the effects of pathology outside the brain parenchyma, in particular meningeal inflammation or through cerebrospinal fluid mediated factors.	25823475
Gingivitis	Altered Intercellular Communication	Among the 100 subjects, only 39% correctly identified that hormonal changes contribute to pregnancy gingivitis.	25823479
Inflammation	Altered Intercellular Communication	Some literatures supported that genes involved in both oxidative stress and prostaglandin metabolism play an important role in the process of inflammation.	25823564
Inflammation	Altered Intercellular Communication	Here we perform a study of the inflammatory response following injury in Xenopus larvae, which are able to achieve scarless wound healing and to regenerate appendages, as a preamble into understanding the role that inflammation plays during tissue repair and regeneration in this organism.	25823652
Communicable Diseases, Inflammation, Traumatic injury	Altered Intercellular Communication	Using this approach we found that the inflammatory response following injury and infection in Xenopus larvae is very similar to that seen in humans, suggesting that this model provides an easily tractable and medically relevant system to investigate inflammation following injury and infection in vivo.	25823652
Biliary Atresia, Inflammation, Fibrosis Assessment, Cholestasis	Altered Intercellular Communication	Liver histology: CMV IgM+ve biliary atresia was characterised by a greater degree of inflammation (P < 0.0001) and fibrosis (P = 0.02), whereas CMV IgM-ve isolated biliary atresia had a higher degree of lobular cholestasis (P = 0.001).	25824438
Degenerative polyarthritis, Inflammation, Synovitis	Altered Intercellular Communication	Cadherin-11 expression in OA synoviums and its correlation with synovitis score and systemic inflammation markers were explored.	25824718
Inflammation, Primary malignant neoplasm, Squamous cell carcinoma of esophagus	Altered Intercellular Communication	Preoperative LMR better predicts cancer survival compared with the cellular components of systemic inflammation in patients with ESCC undergoing esophagectomy.	25824745
Inflammation	Altered Intercellular Communication	Regarding pathogenesis, it is thought that disruption of kinetics through T lymphocyte-mediated development of chronic inflammation may be involved.	25824754
Inflammation	Altered Intercellular Communication	Although the Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) regulates important processes for inflammation such as MMP-release, its expression and regulation on monocyte subsets has not been characterized.	25824988
Ischemia, Inflammation, Necrosis	Altered Intercellular Communication	We suppose that the early complications that often occur in such cases might result from a nonspecific, inflammatory reaction induced by acute tissue ischemia and necrosis, and the late local complications that occur years later may relate more to chronic inflammation, due to nonvascularized tissue, than to immunologic rejection.	25825423
Inflammation, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	Inflammation plays a critical role in the development and progression of obstructive sleep apnea (OSA).	25825846
Neoplasms	Altered Intercellular Communication	Expression profiling of a panel of 184 inflammation-related genes was performed in 15 chemoresistant and 19 chemosensitive HGSC tumours using the NanoString nCounter platform.	25826225
Periodontitis, Bacterial Infections	Altered Intercellular Communication	Periodontitis represents a chronic bacterial infection that induces immuno-inflammatory conditions affecting gingiva and tooth-supporting tissues.	25826490
Tumor necrosis, Carcinogenesis, Inflammation, Neoplasms	Altered Intercellular Communication	The tumor necrosis factor alpha (TNF-a) represents an important inflammation mediator associated to carcinogenesis and even to tumor progression.	25826493
Inflammation	Altered Intercellular Communication	Inflammation was determined by the local microbial flora enhanced by the action of prosthetic appliances or by the prolonged edentulous state.	25826498
Inflammation	Altered Intercellular Communication	Gingival inflammation is highly prevalent among adult populations in all regions of the world.	25826499
Inflammation, Periodontal Diseases	Altered Intercellular Communication	The methods for assessing the gingival inflammation and periodontal disease would need more precision and less user-dependence.	25826499
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Synovial inflammation in patients with different stages of knee osteoarthritis.	25826502
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The overexpression of mediators of inflammation and the increased mononuclear cell infiltration were seen in early OA, compared with late OA.	25826502
Inflammation	Altered Intercellular Communication	Topographic associations and density of inflammatory elements analyzed in relation with neoforming vessels suggest their implication in reparatory angiogenesis characteristic to chronic inflammation.	25826509
Pericardial Effusion, CTCAE, Acute inflammation	Altered Intercellular Communication	Cardiac Magnetic Resonance (CMR) allows evaluation of the functional and flow changes in pericardial constriction as well as detection of acute pericardial inflammation, fusion and thickening of pericardial layers and pericardial effusion.	25827067
Pericarditis, CTCAE, Acute inflammation, Pericarditis, Constrictive	Altered Intercellular Communication	The diagnosis of CP was confirmed in 53 patients while 12 patients presented signs of predominant pericardial active inflammation suggesting a diagnosis of transient constrictive pericarditis and five presented effusive-constrictive pericarditis.	25827067
Inflammation, Chronic pericarditis	Altered Intercellular Communication	A multiparametric CMR approach allowed to distinguish between active inflammation, chronic pericarditis with constriction and effusion without inflammation.	25827067
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	(i) Endoscopically normal appearing colonic mucosa of patients with UC-IR remains abnormal: CLE demonstrates impaired crypt regeneration, persistent inflammation, distinct abnormalities in angioarchitecture and increased vascular permeability; molecular imaging showed increased COX2 and mtDNA mutations; (ii) CLE may serve as a new gold standard for the assessment of mucosal healing in UC.	25827810
Degenerative polyarthritis, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Comparative immunohistochemical evaluation of the zonal distribution of extracellular matrix and inflammation markers in human meniscus in osteoarthritis and rheumatoid arthritis.	25827912
Degenerative polyarthritis, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The distribution patterns of the extracellular matrix components as well as the CD44-positive cells and the inflammation markers in the peripheral zone resembled the distribution in synovial tissue, indicating that both synovia and meniscus were involved in pathological changes in osteoarthritis and rheumatoid arthritis.	25827912
Degenerative polyarthritis, Rheumatoid Arthritis, Inflammation, Arthropathy	Altered Intercellular Communication	the distribution of extracellular glycoconjugates and of cells modulating their synthesis showed similar results in both arthropathies, not enabling a differentiation between rheumatoid arthritis and osteoarthritis but underlining the role of these markers in inflammation and degradation in human meniscus.	25827912
Inflammation, Schizophrenia	Altered Intercellular Communication	Inflammation appears to play significant role in schizophrenia.	25827958
Inflammation, Chronic Obstructive Airway Disease, Smooth muscle (tissue), Abnormality of mitochondrial metabolism	Altered Intercellular Communication	Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease.	25828268
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Inflammation and oxidative stress play critical roles in patients with chronic obstructive pulmonary disease (COPD).	25828268
Respiratory Hypersensitivity, Pneumonitis	Altered Intercellular Communication	Mice were exposed to ozone, and lung inflammation, airway hyperresponsiveness (AHR), and mitochondrial function were determined.	25828268
AHR wt Allele, Pneumonitis, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	Mice exposed to ozone, a source of oxidative stress, had lung inflammation and AHR associated with mitochondrial dysfunction and reflected by decreased mitochondrial membrane potential (DPsm), increased mitochondrial oxidative stress, and reduced mitochondrial complex I, III, and V expression.	25828268
Inflammation, AHR wt Allele, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	Reversal of mitochondrial dysfunction by the mitochondria-targeted antioxidant MitoQ reduced inflammation and AHR.	25828268
ARCN1 gene, Inflammation, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	Mitochondrial dysfunction in patients with COPD is associated with excessive mitochondrial ROS levels, which contribute to enhanced inflammation and cell hyperproliferation.	25828268
Hypophysitis, CTCAE, Inflammation	Altered Intercellular Communication	Hypophysitis is a rare chronic inflammation of the pituitary gland corresponding currently to six histopathological subtypes.	25828777
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Prostate Biopsy Markers of Inflammation are Associated with Risk of Clinical Progression of Benign Prostatic Hyperplasia: Findings from the MTOPS Study.	25828974
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	We measured inflammatory markers from prostate biopsies to study if inflammation is related to clinical progression of benign prostatic hyperplasia.	25828974
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Inflammation as measured by CD45, CD4 and CD68 increased the risk of clinical progression of benign prostatic hyperplasia.	25828974
Inflammation	Altered Intercellular Communication	CD4 showed the highest risk where men in the highest tertile of moderate/severe inflammation were at twice the risk of progression compared to men in the lower 2 tertiles combined (HR 2.03, p=0.001).	25828974
Inflammation, Incontinence	Altered Intercellular Communication	Inflammation was more strongly associated with progression defined by acute urinary retention or incontinence (HR ranging from 2.39 [CD8, p=0.03] to 3.08 [CD4, p=0.01]) than an AUA symptom score increase (CD4, HR 1.86, p=0.01).	25828974
Inflammation	Altered Intercellular Communication	Although our data show that inflammation increases the risk of progression, our findings suggest that inflammation has a greater role in men who have conditions requiring anti-inflammatory medications.	25828974
Inflammation, Anemia	Altered Intercellular Communication	Baseline anemia prevalence was 51% with 15% prevalence of concurrent anemia and inflammation.	25828994
Inflammation, Anemia, Failure (biologic function)	Altered Intercellular Communication	In analysis of clinical failure, multivariate-adjusted hazard ratios were 6.41 (95% confidence interval [CI], 2.82-14.57) for concurrent anemia and inflammation, 0.77 (95% CI, .37-1.58) for anemia without inflammation, and 0.45 (95% CI, .11-1.80) for inflammation without anemia compared to those without anemia and inflammation.	25828994
Inflammation, Anemia	Altered Intercellular Communication	ART-naive, HIV-infected individuals with concurrent anemia and inflammation are at particularly high risk of failing treatment, and understanding the pathogenesis could lead to new interventions.	25828994
Inflammation, Anemia, HIV Infections	Altered Intercellular Communication	Reducing inflammation and anemia will likely improve HIV disease outcomes.	25828994
Inflammation, Opportunistic Infections, Anemia	Altered Intercellular Communication	Alternatively, concurrent anemia and inflammation could represent individuals with occult opportunistic infections in need of additional screening.	25828994
Airway structure, Signs and Symptoms, Respiratory	Altered Intercellular Communication	Respiratory symptoms and airway inflammation positively correlated to UFP content in EBC of symptomatic children.	25830607
Cardiovascular morbidity, Chronic Kidney Diseases	Altered Intercellular Communication	The risk for cardiovascular morbidity and mortality is increased in chronic kidney disease; in this process micro-inflammation plays an essential role.	25830914
Ulcer, Inflammation, Necrosis	Altered Intercellular Communication	In addition, bronchoscopy showed ulcers in the trachea, and histopathology disclosed findings of necrosis and inflammation of the subepithelial tissue of the trachea.	25832936
Inflammation, Crohn Disease	Altered Intercellular Communication	Recent studies suggest that markers of mesenteric inflammation, such as increased adipose tissue, may be associated with poor outcomes in Crohn's disease (CD).	25833139
Inflammation, Hypertriglyceridemia	Altered Intercellular Communication	Hypertriglyceridemia, low HDL cholesterol and DM may be good markers of local and systemic inflammation as seen in CD.	25833139
PROS1 gene, Inflammation, Calcium pyrophosphate deposition disease, Degenerative polyarthritis, Arthritis, Psoriatic	Altered Intercellular Communication	According to recent hypothesis, the inflammation has a pivotal role in the onset and progression of erosive hand osteoarthritis (EHOA), psoriatic arthritis (PsA) and chondrocalcinosis (CC)/pseudogout.	25833145
Inflammation, Fibrosis Assessment, Neoplasms	Altered Intercellular Communication	Response assessment after stereotactic ablative body radiotherapy (SABR) in lung can be confounded by radiation-induced inflammation, fibrosis and subsequent alteration of tumour motion.	25833329
Inflammation	Altered Intercellular Communication	A proinflammatory diet is associated with systemic inflammation and reduced kidney function in elderly adults.	25833776
Inflammation	Altered Intercellular Communication	We tested whether the Adapted Dietary Inflammatory Index (ADII) is associated with kidney function and whether effects of diet on chronic low-grade inflammation explain this association.	25833776
Inflammation	Altered Intercellular Communication	A proinflammatory diet was associated with systemic inflammation as well as with reduced kidney function in a combined analysis of 2 community-based cohorts of elderly individuals.	25833776
Sepsis, Inflammation	Altered Intercellular Communication	Low zinc and selenium concentrations in sepsis are associated with oxidative damage and inflammation.	25833826
Sepsis, Inflammation	Altered Intercellular Communication	Oxidative stress with dysregulated inflammation are hallmarks of sepsis.	25833826
Sepsis, Inflammation, Critical Illness	Altered Intercellular Communication	Zinc, selenium, and a series of biomarkers of oxidative stress and inflammation were measured in plasma from critically ill patients with and without sepsis.	25833826
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Peritoneal inflammation and fibrosis are responses to the uremic milieu and exposure to hyperosmolar dialysis fluids in patients on peritoneal dialysis.	25834072
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Ultrasound-detected inflammation predicts radiographic progression in hand osteoarthritis after 5 years.	25834142
Inflammation, Swelling	Altered Intercellular Communication	Significant associations were also observed between ultrasound inflammation and progression of all individual radiographic features, and between clinical soft tissue swelling at baseline and radiographic progression.	25834142
Inflammation, Weight decreased	Altered Intercellular Communication	Factors associated with greater reductions in BMI over time and a greater risk of weight loss were higher inflammatory markers, smoking, older age, higher BMI, and less subsequent improvement in inflammation.	25834210
Inflammation	Altered Intercellular Communication	Four days subsequent to the procedure, the patient showed a systemic inflammation response syndrome.	25834343
Inflammation, Carcinogenesis, Colorectal Carcinoma	Altered Intercellular Communication	Inflammation is known to contribute to carcinogenesis in human colorectal cancer.	25834404
Inflammation, Arthritis, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Association between mean platelet volume levels and inflammation in SLE patients presented with arthritis.	25834502
Meibomian Cyst, Inflammation	Altered Intercellular Communication	Histopathological diagnoses were chalazion and inflammation with mixed cells, respectively.	25834990
Inflammation, Illness (finding)	Altered Intercellular Communication	Inflammation associated with any acute illness can lead to poor appetite and low food intake in older people.	25835231
Uveitis	Altered Intercellular Communication	Association between Smoking and Uveitis: Results from the Pacific Ocular Inflammation Study.	25835263
Inflammation	Altered Intercellular Communication	In AS, inflammation upregulates the expression of BMPs in PBMCs which may lead to the radiographic progression with new bone formation.	25835314
Inflammation, Depression, CTCAE, Cardiovascular system	Altered Intercellular Communication	This study investigated whether inflammation may explain the relationship between depression and incident cardiovascular hospitalisations.	25835436
Inflammation, ovarian neoplasm	Altered Intercellular Communication	One of the proposed mechanisms behind these associations is systemic inflammation, which has also been implicated in ovarian cancer etiology.	25837263
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	The increase in the concentration level of calprotectin in serum (ICP) in patients with inflammatory bowel disease (IBD) is closely associated with increased rates of acute phase of inflammation and combined with worsening of clinical and endoscopic disease activity.	25842402
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Application of the method guarantees complete excision of the rectal stump mucosa, what excludes the risk of the stump inflammation occurrence, as a sign of residual ulcer colitis in immediate and late postoperative period.	25842878
Inflammation	Altered Intercellular Communication	Contribution of microbial sensibilization and latent inflammation in the development and destabilization of atherogenesis-associated diseases seems evident.	25842957
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Adventitial VV initiates the development of coronary artery diseases as an outside-in supply route of inflammation.	25843557
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Neuropathological findings include frank vasculitis and/or perivascular inflammation with mononuclear or multinucleated giant cells that are associated with amyloid-beta (Ab)-laden vessels.	25846442
Inflammation, Liver carcinoma, Liver Cirrhosis, FAM126A gene	Altered Intercellular Communication	Hepatocellular carcinoma (HCC) tends to develop in the liver when there is a high level of background inflammation (cirrhosis).	25847009
Inflammation, Neoplasms	Altered Intercellular Communication	Connective tissue growth factor (CTGF) is a matricellular protein involved in inflammation, tumour growth and angiogenesis.	25847009
Steatohepatitis, Hepatitis	Altered Intercellular Communication	Age-related sensitivity to endotoxin-induced liver inflammation: Implication of inflammasome/IL-1b for steatohepatitis.	25847140
Hepatitis	Altered Intercellular Communication	We also observed severe liver inflammation in aged rats as indicated by increased ALT levels in serum and increased Kupffer cells in the liver.	25847140
Overactive, Hepatitis	Altered Intercellular Communication	In summary, we demonstrated that LPS-induced liver inflammation and lipid accumulation were associated with a chronically overactive inflammasome/IL-1b pathway in aged rat livers.	25847140
Inflammation, Metaplasia, Adenocarcinoma Of Esophagus	Altered Intercellular Communication	Ductal metaplasia in oesophageal submucosal glands is associated with inflammation and oesophageal adenocarcinoma.	25847432
prostatitis	Altered Intercellular Communication	Prostatic inflammation is widespread in the male population.	25847892
prostatitis	Altered Intercellular Communication	Two groups of 50 patients each with symptoms of prostatic inflammation and ecocolorDoppler indicative of prostatitis were identified.	25847892
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Home-based pulmonary rehabilitation improves clinical features and systemic inflammation in chronic obstructive pulmonary disease patients.	25848241
ARCN1 gene, Inflammation	Altered Intercellular Communication	COPD is characterized by pulmonary and systemic inflammation.	25848241
Inflammation, Diffuse alveolar hemorrhage, Interstitial Fibrosis Assessment	Altered Intercellular Communication	Serial imaging revealed progressive interstitial fibrosis secondary to recurrent alveolar hemorrhage and inflammation from crack cocaine.	25848717
Inflammation, Lower gastrointestinal hemorrhage, Endothelial dysfunction	Altered Intercellular Communication	We also evaluated to which extent these associations could be explained by low-grade inflammation (LGI) or endothelial dysfunction (ED).	25848912
Inflammation	Altered Intercellular Communication	Lung function, symptoms and inflammation during exacerbations of non-cystic fibrosis bronchiectasis: a prospective observational cohort study.	25849856
Inflammation, Clonal Anergy	Altered Intercellular Communication	Recent studies have initiated a paradigm shift to comprehend the immunological interactions of Wolbachia and its antigens in inflammation, apoptosis, lymphocyte anergy, etc.	25849993
Chronic dacryocystitis, Suppurative inflammation, Congenital lacrimal fistula	Altered Intercellular Communication	Therefore, we present an 8-week-old child, suffering recurrent purulent inflammation due to an amniotocele (1), a 5-year-old child having a congenital lacrimal fistula (2) and another 5-year-old child with a severe chronic dacryocystitis of both eyes after several lacrimal duct surgeries showing remaining intrasaccal silicone tubes (3).	25851053
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Biopsy specimens were scored for histological fibrosis and inflammation.	25851300
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	For VTQ, both histological fibrosis (P < 0.0001) and inflammation (P = 0.04) scores were significant predictors of shear wave speed (model adjusted R (2) = 0.49).	25851300
Inflammation, Diverticulitis	Altered Intercellular Communication	Complicated cecal diverticulitis is managed surgically and the type of resection depends mainly on the extent of inflammation.	25851946
Inflammation, Complications of Diabetes Mellitus	Altered Intercellular Communication	Inflammation is regarded as one of the main reasons for the progression of diabetes complications.	25853704
Inflammation, Diabetic Retinopathy, Kidney Diseases	Altered Intercellular Communication	We aimed to evaluate the association of neutrophil to lymphocyte ratio (NLR) as indicator of systemic inflammation with diabetic retinopathy and nephropathy.	25853704
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	This study aimed at a systematic evaluation of soluble HLA-G (sHLA-G) in plasma of rheumatoid arthritis (RA) patients with long-lasting chronic inflammation.	25853899
Refractory anemias, Inflammation	Altered Intercellular Communication	Thus, in a substantial number of late RA patients, the circulating sHLA-G molecules are impaired regarding LILRB1 recognition, meaning that although increased levels are observed; these molecules are not qualified to exert their protective functions against inflammation.	25853899
Inflammation	Altered Intercellular Communication	Intraventricular fibrinolysis with tissue plasminogen activator is associated with transient cerebrospinal fluid inflammation: a randomized controlled trial.	25853905
Inflammation	Altered Intercellular Communication	Adjusting for age, gender, and smoking, a higher symptom burden was associated with increased sinonasal inflammation as captured by the MLM (b = 0.453, p < 0.013).	25854318
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	[Etanercept inhibits synovial inflammation and reduces the expression of adhesion related molecules in synovial tissues of patients with rheumatoid arthritis].	25854571
Inflammation, Rheumatoid Arthritis, Tumor necrosis	Altered Intercellular Communication	To observe the changes of synovial inflammation score and expression of related molecular markers in patients with rheumatoid arthritis treated with tumor necrosis factor (TNF) antagonist etanercept.	25854571
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Etanercept could effectively inhibit proliferation of synoviocytes and infiltration of lymphocytes in synovium of rheumatoid arthritis, and decrease the expressions of proliferation-and adhesion-related molecular markers, which histologically alleviated the synovial inflammation of rheumatoid arthritis.	25854571
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	We have previously shown that the cartilage DNA methylome delineates two clusters of osteoarthritic (OA) hip patients, characterised by differential methylation of inflammatory genes, while others have demonstrated a link between zinc homeostasis and inflammation in OA.	25854584
Degenerative polyarthritis	Altered Intercellular Communication	One of the OA clusters is characterised by the promoter hypomethylation and increased expression of inflammation-associated genes including IL1A and TNF.	25854584
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	The main histopathological features of abdominal aortic aneurysm (AAA) are tissue proteolysis mediated by matrix metalloproteinases (MMPs) and inflammation.	25854712
Inflammation	Altered Intercellular Communication	Mean inflammation score; serum levels of 3 serum markers were then compared.	25854786
Inflammation, Chronic gastritis	Altered Intercellular Communication	The combination of triple therapy with CoQ10 demonstrated an effective outcome on the mucosal inflammation, and stress oxidative in patients with chronic gastritis.	25854786
Celiac Disease, Gluten, Inflammation	Altered Intercellular Communication	Gluten consumption is associated with increased plasma a2-macroglobulin in young adults, which appears to be independent of celiac disease, suggesting possible effects of gluten on inflammation.	25855121
Inflammation, myonecrosis	Altered Intercellular Communication	Statin-associated NAM is characterized by irritable myopathy on electromyography (EMG) and muscle necrosis with minimal inflammation on muscle biopsy.	25855481
Inflammation, Carcinogenesis, Neoplasms	Altered Intercellular Communication	Evidence suggests an etiologic role for inflammation in ovarian carcinogenesis and heterogeneity between tumor subtypes and anthropometric indices.	25855626
Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	Inflammation has an integral role in the pathophysiology of AKI.	25855775
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Additional adjustment for putative mediators, including subclinical CVD, diabetes, lipids and inflammation, did not significantly affect these estimates.	25855796
Sepsis, vascular inflammations	Altered Intercellular Communication	Angiopoietin-2 is an endothelial-derived protein that potentiates vascular inflammation and leakage and may be involved in sepsis pathogenesis.	25855898
Inflammation	Altered Intercellular Communication	The genes hypomethylated in athero-prone arteries to compare with atherosclerotic-resistant arteries were predominately involved in regulation of inflammation and immune processes, as well as development.	25856389
Pain Distress Question, Endophthalmitis, CTCAE, Retinal Hemorrhage, Inflammation	Altered Intercellular Communication	A 70-year-old woman presented with signs of acute-onset endophthalmitis within 24 hours of surgery, with retinal hemorrhages and vascular changes in the absence of pain or significant inflammation.	25856829
Inflammation, Endophthalmitis, CTCAE, Retinal Vasculitis, Hemorrhage	Altered Intercellular Communication	Although rarely, acute-onset postoperative endophthalmitis can present as retinal vasculitis with intraretinal hemorrhages and mild inflammation.	25856829
Autoimmune Diseases, Rheumatoid Arthritis, Orchitis	Altered Intercellular Communication	Rheumatoid arthritis is an autoimmune disease of unknown etiology, characterized by articular inflammation.	25857584
Inflammation	Altered Intercellular Communication	High level of ICAM-1 may be indicative of systemic inflammation and portends increase risk of incipient DKD.	25857767
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Preclinical data suggest these cells improve vascular density, which would be expected to decrease fibrosis and inflammation.	25857908
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	There were no significant differences in fibrosis or inflammation between groups; however, density of activated fibroblasts was decreased in both CD34+ and CD34- injected areas.	25857908
Refractory anemias, Inflammation	Altered Intercellular Communication	Biopsies were also obtained from patients with RA with longer symptom duration (>12 weeks) and individuals with no clinically apparent inflammation.	25858640
Inflammation, Asthma	Altered Intercellular Communication	Some patients with refractory asthma have evidence of uncontrolled eosinophilic inflammation in the distal airways.	25858909
Airway structure, Asthma	Altered Intercellular Communication	Specifically treating distal airway inflammation may improve asthma control.	25858909
Eosinophilic disorder, Inflammation	Altered Intercellular Communication	These data demonstrate that patients with ongoing eosinophilic inflammation are not truly refractory, and that suppression of airway eosinophilia may be maintained with additional inhaled corticosteroid.	25858909
Inflammation, Neoplasms, Communicable Diseases, Congenital vascular anomaly, Disease	Altered Intercellular Communication	Solitary pulmonary nodules (SPNs) can be manifested in a variety of disorders including neoplasms, infection, inflammation, and vascular or congenital abnormalities.	25860214
Inflammation, Arthritis	Altered Intercellular Communication	All rheumatology and internal medicine practitioners belonging to the Club Rhumatismes et Inflammation in France were sent newsletters asking for reports of HEV infection and inflammatory arthritides.	25860212
Inflammation, MS gene	Altered Intercellular Communication	Biomarkers of inflammation and axonal degeneration/damage in patients with newly diagnosed multiple sclerosis: contributions of the soluble CD163 CSF/serum ratio to a biomarker panel.	25860354
MS gene	Altered Intercellular Communication	Expression of soluble CD163 (sCD163), a macrophage/microglia biomarker, is increased in inflammatory conditions, and sCD163 levels in the cerebrospinal fluid (CSF) have recently been shown to be elevated in patients with multiple sclerosis (MS): the sCD163 CSF/serum ratio was elevated in patients with relapsing-remitting MS (RRMS), primary progressive MS (PPMS), and clinically isolated syndrome (CIS) compared with symptomatic controls.	25860354
Saccular Aneurysm, Rupture, Blood Clot	Altered Intercellular Communication	Although several studies have suggested that aneurysmal wall inflammation and laminar thrombus are associated with the rupture of saccular aneurysms, the mechanisms leading to the rupture remain obscure.	25860660
Aneurysmal, Inflammation, Endothelial dysfunction, Rupture	Altered Intercellular Communication	These findings suggest that subintimal fibrin deposition and chronic inflammation have a strong impact on degeneration of the aneurysmal wall leading to their rupture, and this finding may be caused by endothelial dysfunction.	25860660
Inflammation, Ulcer	Altered Intercellular Communication	We studied the eventual apoptosis of epithelial cells from the point of view of ulcer and inflammation.	25861801
Inflammation, Structure of vasa vasorum	Altered Intercellular Communication	IL-17 overexpression was observed mainly in arteries with transmural inflammation and vasa vasorum vasculitis.	25862016
Inflammation, Cutaneous Small Vessel Vasculitis	Altered Intercellular Communication	IL-9 overexpression and Th9 polarization predominated in arteries with transmural inflammation and small-vessel vasculitis.	25862016
Inflammation, Cutaneous Small Vessel Vasculitis	Altered Intercellular Communication	IL-4, TGF-b and thymic stromal lymphopoietin, which are involved in the differentiation of Th9 cells, were overexpressed in arteries with transmural inflammation and small-vessel vasculitis.	25862016
Inflammation	Altered Intercellular Communication	IL-9R was also overexpressed in GCA arteries with transmural inflammation and was accompanied by increased expression of IL-8.	25862016
Inflammation, Carcinoma of lung	Altered Intercellular Communication	The high expression of PD-L1 in EBV and inflammation associated LELC may provide a rationale for immunotherapy in this subtype of lung cancer.	25862146
SLC25A20 gene, Colitis	Altered Intercellular Communication	Females show a lower incidence probably related to hormonal factors; therefore, a role of estrogen receptors (ERs) has been supposed in carcinoma-associated colitis (CAC) development.	25862314
Alzheimers Disease", Inflammation, Data types - Address, Dyslipidemias	Altered Intercellular Communication	Epidemiological findings suggest a relationship between Alzheimer disease (AD), inflammation, and dyslipidemia, although the nature of this relationship is not well understood.	25862742
Inflammation, Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	Axillary lymph node metastasis was not associated with age, menopausal status, primary tumor size or its location, the degree of inflammation within the tumor or mitotic count.	25862826
Parkinson Disease, Inflammation	Altered Intercellular Communication	Potential of the cannabinoid CB(2) receptor as a pharmacological target against inflammation in Parkinson's disease.	25863279
Parkinson Disease, Inflammation, palladium	Altered Intercellular Communication	Inflammation is an important pathogenic factor in Parkinson's disease (PD), so that it can contribute to kill dopaminergic neurons of the substantia nigra and to enhance the dopaminergic denervation of the striatum.	25863279
Infiltration	Altered Intercellular Communication	Parkinsonian inflammation can be reproduced experimentally in rodents by intrastriatal injections of lipopolysaccharide (LPS) which, through an intense activation of glial elements and peripheral infiltration, provokes a rapid deterioration of the striatum that may extend to the substantia nigra too.	25863279
ACSM3 gene, Inflammation, Subarachnoid Hemorrhage	Altered Intercellular Communication	Subarachnoid haemorrhage (SAH) is associated with sympathetic nervous activation and inflammation.	25864536
Inflammation	Altered Intercellular Communication	Although there is emerging evidence that these sulphur compounds stimulate immune cells and induce the inflammatory cascade, the immunological mechanisms of local and systemic inflammation have not been described.	25864743
Inflammation, Critical Illness, Blood Coagulation Disorders	Altered Intercellular Communication	The role of platelet-derived microparticles (PDMPs) in the crosstalk between coagulopathy and inflammation in critically ill patients remains unclear.	25864886
Diabetic Nephropathy, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Inflammation and fibrosis play important roles in the progression of diabetic nephropathy.	25865428
Inflammation, Retinitis Pigmentosa, polychondritis, Autoimmune Disorder, CTCAE	Altered Intercellular Communication	Relapsing polychondritis (RP) is a rare systemic autoimmune disorder characterized by the episodic and progressive deterioration of cartilage inflammation.	25867227
Inflammation	Altered Intercellular Communication	Among the GFM lesions, GNAS mutations were more common in lesions without active inflammation.	25867268
Inflammation	Altered Intercellular Communication	Innate immunity plays a pivotal role in obesity-induced low-grade inflammation originating from adipose tissue.	25867514
Inflammation, Obesity	Altered Intercellular Communication	In vivo, TLR-3 deficiency did not significantly influence HFD-induced obesity, insulin sensitivity or inflammation.	25867514
Inflammation	Altered Intercellular Communication	However, TLR-3 appears to play a redundant role in obesity-induced inflammation and insulin resistance.	25867514
Sepsis, Tumor necrosis, Communicable Diseases	Altered Intercellular Communication	Monocyte Tumor Necrosis Factor-a-Converting Enzyme Catalytic Activity and Substrate Shedding in Sepsis and Noninfectious Systemic Inflammation.	25867908
Acute Kidney Tubular Necrosis, Interstitial Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	Renal biopsy indicated severe acute tubular necrosis with a significant striped interstitial fibrosis and mild interstitial inflammation.	25868963
Inflammation, Neoplasms	Altered Intercellular Communication	The prognostic nutritional index (PNI), an indicator of nutritional status and systemic inflammation, is associated with survival in several types of tumors.	25869028
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	There is accumulating evidence that inflammation is linked to cancer development and progression.	25869448
Inflammation	Altered Intercellular Communication	These interfaces among inflammation and thrombogenesis have been suggested as targets for pharmacological intervention to reduce disease progression.	25869506
Vitritis, Intraocular inflammation, Abnormally opaque structure (morphologic abnormality), Uveitis	Altered Intercellular Communication	Intermediate uveitis is a subset of intraocular inflammation where vitritis is the most consistent sign, with or without snowball opacities or snow banks over the pars plana.	25870216
Candida albicans, Inflammation, Uveitis	Altered Intercellular Communication	Oral fluconazole and intravitreal amphotericin B injection had failed to resolve her inflammation when Candida albicans was identified as the cause of her persistent intermediate uveitis.	25870216
Inflammation, Knee joint	Altered Intercellular Communication	Does subclinical inflammation contribute to impairment of function of knee joints in aged individuals?	25870315
Inflammation, Impaired	Altered Intercellular Communication	These data suggest a substantial contribution of inflammation in progressive impairment of joint function with age.	25870315
Inflammation	Altered Intercellular Communication	Pre-exposure to Ti particles attenuated NF-kB activation in LPS-stimulated macrophages, indicating that wear particles suppress immune response, which may lead to chronic inflammation.	25871260
Inflammation	Altered Intercellular Communication	Wear particles induce ROS generation through the NOX signaling pathway, resulting in persistent inflammation and delayed loosening.	25871260
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Diet is a strong moderator of systemic inflammation, an established risk factor for colorectal cancer (CRC).	25871645
Inflammation, Colorectal Carcinoma, Chronic disease	Altered Intercellular Communication	The DII may serve as a novel way to evaluate dietary risk for chronic disorders associated with inflammation, such as CRC.	25871645
Degenerative polyarthritis, Inflammation, Bone Marrow	Altered Intercellular Communication	Based on pathological, magnetic resonance imaging (MRI) and arthroscopy studies, progressive osteoarthritis involves all tissues of the joint and includes bone marrow lesions, synovial proliferation, fat pad inflammation, and high subchondral bone turnover.	25872665
Inflammation	Altered Intercellular Communication	Osteopontin (OPN) can recruit macrophages to the site of inflammation and promote tumorigenesis.	25872762
Acute Coronary Syndrome, Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	In acute coronary syndrome (ACS), inflammation and redox response are associated with increased residual platelet reactivity (RPR) on clopidogrel therapy.	25873769
Autosomal Recessive Disorder, Inflammation, Calcinosis, Hyperpigmentation, CTCAE 3	Altered Intercellular Communication	Ochronosis, an autosomal recessive metabolic disorder, causes an excess of homogentisic acid that results in adverse pigmentation, calcification, and inflammation of cartilaginous and other tissues.	25873809
Inflammation, Abnormal degeneration	Altered Intercellular Communication	Calcified human aortic valves showed side-specific elevation of superoxide in the endothelium, co-localized with high VCAM1 expression, linking oxidative stress, inflammation, and valve degeneration.	25874717
Inflammation	Altered Intercellular Communication	TNFa-driven VEC oxidative stress causes loss of endothelial protective function, chronic inflammation, and fibrogenic and osteogenic activation, mitigated differentially by BH4 and peg-SOD.	25874717
Inflammation, Agoraphobia	Altered Intercellular Communication	Evidence for chronic low-grade systemic inflammation in individuals with agoraphobia from a population-based prospective study.	25875094
Inflammation, Anxiety Disorders, Coronary heart disease	Altered Intercellular Communication	Anxiety disorders have been linked to an increased risk of incident coronary heart disease in which inflammation plays a key pathogenic role.	25875094
Inflammation, Agoraphobia	Altered Intercellular Communication	Our results suggest an increase in chronic low-grade inflammation in agoraphobia over time.	25875094
Colorectal Carcinoma	Altered Intercellular Communication	Laparoscopic surgery for colorectal cancer is not associated with an increase in the circulating levels of several inflammation-related factors.	25875151
Colorectal Carcinoma	Altered Intercellular Communication	To test this hypothesis, the levels of multiple inflammation-related circulating factors were analyzed in patients undergoing surgery for colorectal cancer.	25875151
Primary malignant neoplasm, Colorectal Carcinoma	Altered Intercellular Communication	These findings suggest that expression levels of several cytokines are higher in colorectal cancer patients compared to control subjects and no significant increase in several inflammation-related circulating factors is observed following laparoscopic surgery for cancer.	25875151
Gastritis, Neoplasms	Altered Intercellular Communication	Contrast-enhanced computed tomography (CT) revealed that the tumor had a cystic component and marked perigastric inflammation.	25875550
Inflammation	Altered Intercellular Communication	The lesion was diagnosed as gastric heterotopic pancreas with inflammation of the pancreatic tissue.	25875550
Inflammation, Pathology	Altered Intercellular Communication	In human epidemiology studies, the low-grade and chronic systemic inflammation in elderly has been correlated with the development of aging related pathologies.	25875575
Inflammation	Altered Intercellular Communication	By studying the Drosophila fat body and gut, we have uncovered a mechanism by which lamin-B loss in the fat body upon aging induces age-associated systemic inflammation.	25875575
Inflammation, Hyperplasia	Altered Intercellular Communication	This chronic inflammation results in the repression of gut local immune response, which in turn leads to the over-proliferation and mis-differentiation of the intestinal stem cells, thereby resulting in gut hyperplasia.	25875575
Inflammation, Fibrosis Assessment, Heart failure	Altered Intercellular Communication	Galectin-3 (Gal-3) is an emerging biomarker in heart failure that is involved in fibrosis and inflammation.	25875595
Rectovaginal Fistula, Inflammation	Altered Intercellular Communication	Pelvic MRI demonstrated a possible rectovaginal fistula with inflammation surrounding the right sciatic nerve plexus.	25876521
Inflammation, IgG4-Related Sclerosing Disease, Head and neck structure	Altered Intercellular Communication	Role of F-18 FDG PET/CT in assessing IgG4-related disease with inflammation of head and neck glands.	25877159
Inflammation, Atherosclerosis, Refractory anemias, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Rheumatoid Arthritis	Altered Intercellular Communication	This prospective followup study investigated subclinical atherosclerosis in relation to traditional cardiovascular disease (CVD) risk factors and inflammation in patients with rheumatoid arthritis (RA) recruited at diagnosis compared with controls.	25877503
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Low-grade inflammation predicts persistence of depressive symptoms.	25877654
Muscle damage, Inflammation, Pain Distress Question	Altered Intercellular Communication	Comparison of markers for muscle damage, inflammation, and pain using minimally invasive direct anterior versus direct lateral approach in total hip arthroplasty: A prospective, randomized, controlled trial.	25877694
Inflammation, Kaposi Sarcoma, OXSM gene	Altered Intercellular Communication	Inflammation and reactive oxygen species (ROS) production have recently considered as key mechanisms in the pathogenesis of Kaposi's sarcoma (KS).	25879916
Sarcoidosis, Inflammatory abnormality of the eye	Altered Intercellular Communication	Sarcoidosis is a major cause of ocular or periocular inflammation.	25880323
Sepsis, Inflammation	Altered Intercellular Communication	Despite a medical treatment and surgical debridement, the sepsis was not controlled, and severe inflammation developed.	25880377
Inflammation, polyps	Altered Intercellular Communication	Although USD is most likely to represent chronic inflammation, there exists a fair likelihood of finding malignant pathology, particularly in cases where patients have a unilateral polyp.	25880633
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Aortic iron overload with oxidative stress and inflammation in human and murine abdominal aortic aneurysm.	25882069
Tissue damage, Inflammation	Altered Intercellular Communication	Although iron is an essential element for maintaining physiological function, excess iron leads to tissue damage caused by oxidative stress and inflammation.	25882069
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Oxidative stress and inflammation play critical roles for the development of abdominal aortic aneurysm (AAA).	25882069
Inflammation	Altered Intercellular Communication	However, it has not been investigated whether iron plays a role in AAA formation through oxidative stress and inflammation.	25882069
Inflammation, Atheroma	Altered Intercellular Communication	Atheroma may be associated with mild chronic inflammation present in the intima or associated with plaques and adventitia.	25882155
Inflammation, Osteoporosis, Atherosclerosis	Altered Intercellular Communication	Systemic inflammation may be a common mechanism for the development of osteoporosis (OP) and atherosclerosis.	25882272
Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	Primary Tumor Resection in Patients With Metastatic Colorectal Cancer Is Associated With Reversal of Systemic Inflammation and Improved Survival.	25882598
ARCN1 gene, Inflammation, Wheezing, Hypoxemia, Asthma	Altered Intercellular Communication	Airflow obstruction was correlated with the patient's age at diagnosis, as well as the presence of combined COPD and asthma, and wheezing on auscultation, which also resulted in more severe systemic inflammation and hypoxemia.	25882894
Inflammation	Altered Intercellular Communication	Brain morphology links systemic inflammation to cognitive function in midlife adults.	25882911
Inflammation, Impaired cognition	Altered Intercellular Communication	Inflammation is linked to cognitive decline in midlife, but the neural basis for this link is unclear.	25882911
Presenile dementia, Inflammation	Altered Intercellular Communication	One possibility is that inflammation associates with adverse changes in brain morphology, which accelerates cognitive aging and later dementia risk.	25882911
Inflammation	Altered Intercellular Communication	Higher peripheral inflammation was associated with poorer spatial reasoning, short term memory, verbal proficiency, learning and memory, and executive function, as well as lower cortical gray and white matter volumes, hippocampal volume and cortical surface area.	25882911
Inflammation	Altered Intercellular Communication	Exploratory analyses of body mass suggested that adiposity may be a source of the inflammation linking brain morphology to cognition.	25882911
Inflammation, Impaired cognition	Altered Intercellular Communication	Inflammation and adiposity might relate to cognitive decline via influences on brain morphology.	25882911
Intraocular inflammation	Altered Intercellular Communication	Visual acuity was 20/20, there was no intraocular inflammation and the posterior vitreous was not detached.	25884156
Inflammation	Altered Intercellular Communication	Six cases were remission-relapsing type and six were chronic inflammation type.	25884202
Tissue damage	Altered Intercellular Communication	High mobility group box-1 (HMGB1), a kind of pro-inflammatory mediator, is associated with inflammatory conditions and tissue damage.	25884225
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation is one of the major hallmarks of cancer.	25884401
Inflammation, Adenoma of large intestine	Altered Intercellular Communication	These findings suggest colorectal adenoma prevalence may not be associated with significant alterations in systemic inflammation.	25884547
Communicable Diseases, Inflammation	Altered Intercellular Communication	Tertiary lymphoid structures (TLS) are highly organized immune cell aggregates that develop at sites of inflammation or infection in non-lymphoid organs.	25884667
Inflammation, Carcinogenesis, Neoplasms	Altered Intercellular Communication	Inflammation plays an integral role in carcinogenesis and tumor progression.	25885254
Granulomatous inflammation, Caseous necrosis, Tuberculosis	Altered Intercellular Communication	Excisional biopsies performed from two different sites revealed swellings in muscular layers and histopathology showed granulomatous inflammation with caseous necrosis consistent with tuberculosis.	25885776
Inflammation, Spondylitis, Inflammatory disorder	Altered Intercellular Communication	Ankylosing spondylitis (AS) is an inflammatory disease with documented elevated cardiovascular (CV) risk due to systemic inflammation and a higher prevalence of CV risk factors.	25886634
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Hostile individuals with Type 2 diabetes may be susceptible to stress-induced increases in inflammation.	25886832
Stomach Carcinoma, Gastrointestinal inflammation	Altered Intercellular Communication	The FJI procedure promotes nutritional recovery and decreases post-operative complications in gastric cancer patients after total gastrectomy, which may be through ameliorating intestinal inflammation and damage and reducing ICC loss to preserve food reservoir function and intestinal motility.	25886854
Communicable Diseases, Inflammation	Altered Intercellular Communication	Urinary ATP as an indicator of infection and inflammation of the urinary tract in patients with lower urinary tract symptoms.	25886951
Communicable Diseases, Inflammation	Altered Intercellular Communication	We tested the potential of urinary ATP in the assessment of lower urinary tract symptoms, infection and inflammation, and validated sampling methods for clinical practice.	25886951
Urologic Diseases	Altered Intercellular Communication	Adenosine-5'-triphosphate (ATP) is a neurotransmitter and inflammatory cytokine implicated in the pathophysiology of lower urinary tract disease.	25886951
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Further, the aberrant miRNA expression profiles indicate that miRNAs may be contributory to IBD pathogenesis, or at least reflect the underlying inflammation.	25886994
Inflammation, Dental Plaque	Altered Intercellular Communication	Local production of C-reactive protein (CRP) in human coronary arterial plaque was reported as a possible marker for local inflammation and vulnerable plaque.	25886998
Inflammation, Dental Plaque	Altered Intercellular Communication	Integrated backscatter intravascular ultrasound (IB-IVUS) plaque tissue characterization may detect vulnerable plaque with high local plaque inflammation.	25886998
Migraine Disorders, Inflammation, Neuronal Hyperexcitability	Altered Intercellular Communication	Recent insights into the pathogenesis of migraine headache substantiate a neuronal hyperexcitability and inflammation involving compressed peripheral craniofacial nerves, and these trigger points can be eliminated by surgery.	25887206
Inflammation	Altered Intercellular Communication	The mechanism of IR may be associated with inflammation, whereas the neutrophil-lymphocyte ratio (NLR) is a new indicator of subclinical inflammation.	25887236
Sepsis, Inflammation, Acute Lung Injury, Cessation of life	Altered Intercellular Communication	Sepsis refers to severe systemic inflammation leading to acute lung injury (ALI) and death.	25887405
Inflammation, Peri-Implantitis	Altered Intercellular Communication	Peri-implantitis is a chronic inflammation, resulting in loss of supporting bone around implants.	25887438
Inflammation, GDC Disease Response Terminology	Altered Intercellular Communication	Inflammation is supposed to participate in the development of DR.	25887518
Respiratory Distress Syndrome, Adult, Pneumonitis	Altered Intercellular Communication	Recent studies have revealed that lung inflammation mediated by CD4+ T cells may contribute to the pathogenesis of acute respiratory distress syndrome (ARDS).	25887535
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	The imbalance between CD4 + CD25 + Foxp3 + regulatory T (Treg) cells and T helper (Th)17 cells has been found in a number of different inflammation and autoimmune diseases, while the role of the Th17/Treg balance in ARDS remains largely unknown.	25887535
Inflammation, Depression, CTCAE, Atherosclerosis	Altered Intercellular Communication	Growing evidence suggests that there is an intricate interplay between atherosclerosis, inflammation and depression.	25888123
Minimal Disseminated Disease, Inflammation	Altered Intercellular Communication	The aim of this study was to investigate the role of atherosclerosis-induced inflammation in the mediation of MDD.	25888123
Inflammation, Hypertension, CTCAE, Obesity	Altered Intercellular Communication	We investigated the relation between inflammation and incident hypertension, independent of obesity, and tested the associations of cardiorespiratory fitness (fitness) and indexes of inflammation for the development of hypertension in 2,475 normotensive men.	25888302
Inflammation, Carcinoma of lung, Lung, HIV Infections	Altered Intercellular Communication	Our data suggest that pulmonary damage and inflammation associated with HIV infection may be causative for the increased risk of lung cancer.	25888645
Inflammation, Fever, CTCAE, Trap medical device	Altered Intercellular Communication	TRAPS is clinically characterized by recurrent episodes of long-lasting fever and systemic inflammation.	25888769
Degenerative polyarthritis, Arthritis	Altered Intercellular Communication	Based on our data, cathepsin activity monitored by ABPs correlated well with OA severity and joint inflammation, directing towards a novel etiological target for OA, which possesses significant translational potential in developing means for non-invasive detection of early signs of OA.	25889265
Degenerative polyarthritis	Altered Intercellular Communication	Lysosomal cathepsins have been reported to contribute to Osteoarthritis (OA) pathophysiology due to their increase in pro-inflammatory conditions.	25889265
Inflammation, Atherosclerosis	Altered Intercellular Communication	Pitavastatin not only improved the atherosis as measured by IMT and cIBS values but also attenuated inflammation of plaques as measured by max SUV at the same site.	25889304
Vascular Diseases, Inflammation	Altered Intercellular Communication	Vascular disease is promoted by systemic inflammation that can arise from sites distal to the affected vessels.	25890092
Inflammation, Exanthema, Polymyositis, Idiopathic Inflammatory Myopathies, Dermatomyositis	Altered Intercellular Communication	Dermatomyositis and polymyositis are both types of idiopathic inflammatory myositis characterized by inflammation and weakness of proximal skeletal muscles and skin rash.	25890160
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Obstructive Sleep Apnea (OSAS) is a disease associated with the increase of cardiovascular risk and it is characterized by repeated episodes of Intermittent Hypoxia (IH) which inducing oxidative stress and systemic inflammation.	25890226
Refractory anemias, Rheumatoid Arthritis, Hormone abnormality	Altered Intercellular Communication	Rheumatoid arthritis (RA) is characterized by decreased androgen levels, which was the first hormonal abnormality described.	25890314
Inflammation, Rheumatoid Arthritis, Calcium pyrophosphate deposition disease	Altered Intercellular Communication	Extensor digitorum tendon (EDT) tear in the wrist is frequently associated with inflammation (rheumatoid arthritis, chondrocalcinosis) or distal radio-ulnar osteoarthritis.	25890810
methyldopa, Inflammation, Age related macular degeneration	Altered Intercellular Communication	Dysfunction of the retinal pigment epithelium (RPE) resulting from chronic inflammation is implicated in the pathogenesis of age-related macular degeneration (AMD).	25890876
Seizures, Inflammation, Epilepsy	Altered Intercellular Communication	Recently, a growing body of evidence has suggested that microRNA-146a (miR-146a) is upregulated in the brains of epilepsy patients and of mouse models; furthermore, miR-146a may be involved in the development and progression of seizures through the regulation of inflammation and immune responses.	25891929
Crohn Disease, Inflammation	Altered Intercellular Communication	Two patients had established Crohn's disease, both with long segments (>95 mm) of transmural inflammation located >100 mm from the diverticulum.	25892011
Inflammation, Carcinogenesis, Malignant Neoplasms	Altered Intercellular Communication	Inflammation is an important hallmark of all types of cancers with a well-established role in carcinogenesis.	25892571
Inflammation, Intervertebral Disc Degeneration	Altered Intercellular Communication	Chronic inflammation is a key component of painful intervertebral disc degeneration.	25893355
Sepsis, Inflammation	Altered Intercellular Communication	Plasma Neutrophil Gelatinase-Associated Lipocalin Is Primarily Related to Inflammation during Sepsis: A Translational Approach.	25893429
Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	Plasma neutrophil gelatinase-associated lipocalin (plasma-NGAL) is discussed as new biomarker for AKI diagnosis, but during inflammation its function and diagnostic impact remain unclear.	25893429
Sepsis, Inflammation, Injury of kidney	Altered Intercellular Communication	Plasma-NGAL levels were stronger associated with inflammation markers including IL-6 (Sepsis: r = 0.785 P < 0.001; chronic inflammation after anti-TNF: r = 0.558 P < 0.001), IL-8 (Sepsis: r = 0.714 P<0.004; healthy controls after exercise r = 0.786 P < 0.028; chronic inflammation before anti-TNF: r = 0.429 P < 0.041) and IL-10 (healthy controls before exercise: r = 0.791 P < 0.028) than with kidney injury or function.	25893429
Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	For clinical relevance, it might not only be useful for AKI detection during severe inflammation - indeed it has to be interpreted carefully within this setting - but additionally might offer therapeutic potential.	25893429
Communicable Diseases, Inflammation	Altered Intercellular Communication	Thus, our data suggest that persistent HPV16/18 infection in the cervix due to the presence of the HLA-DQB1 A-allele and chronic inflammation due to the presence of the IL-1b -511 T-allele might predispose women to CaCx development.	25893807
Inflammation	Altered Intercellular Communication	Oxidative stress and chronic inflammation are factors accelerating telomere loss.	25894013
Inflammation	Altered Intercellular Communication	Chronic hemodialysis, typically accompanied by oxidative stress and inflammation, may be also associated with replicative senescence.	25894013
Inflammation, Amyloidosis	Altered Intercellular Communication	Bone marrow biopsy provides important information in renal transplant recipients, especially in cases of neoplastic bone marrow involvement, specific inflammation, and amyloidosis, which are uncommon in this patient group.	25894168
Inflammation	Altered Intercellular Communication	It may be explained by reduced erythropoietin (EPO) synthesis, but recent data suggest that EPO-resistance and diminished iron availability due to inflammation contribute significantly.	25894587
Albrights hereditary osteodystrophy", Parathyroid Hormone Resistance	Altered Intercellular Communication	Reports of patients with mild POH with Albright hereditary osteodystrophy (AHO), specifically pseudohypoparathyroidism type Ia (PHP Ia) with hormonal resistance, suggest the possibility of a common molecular basis.	25894639
Inflammation, Liver damage	Altered Intercellular Communication	The importance of these prognostic variables suggests a close relationship between inflammation, iron overload, liver damage and the extension of the disease.	25895906
Intraocular inflammation	Altered Intercellular Communication	High risk was defined as a history of graft rejection, three or more quadrants of vascularization, or the presence or history of intraocular inflammation.	25896110
Inflammation, Essential Hypertension	Altered Intercellular Communication	Impact of administration of folic acid on selected indicators of inflammation in patients with primary arterial hypertension.	25897102
Inflammation, Essential Hypertension	Altered Intercellular Communication	The results of epidemiological and clinical tests have shown that in patients with primary arterial hypertension, a chronic mild inflammation develops.	25897102
Inflammation	Altered Intercellular Communication	Inflammation and inflammatory biomarkers have emerged as integral components and predictors of incident cardiovascular (CV) disease.	25897795
Inflammation	Altered Intercellular Communication	3-h exposure to DE caused no genotoxicity, oxidative stress or inflammation in PBMCs, whereas exposure to noise might cause oxidatively damaged DNA.	25898780
Waldenstrom Macroglobulinemia, Haiti	Altered Intercellular Communication	Patients with a clinical diagnosis of HT had increased lymphoplasmacytic inflammation, but the relative proportion of IgG4+ plasma cells was not increased compared to patients without HT.	25898816
Vasculitis, Coronary Arteriosclerosis	Altered Intercellular Communication	Influence of cardiovascular risk factors and vessel wall inflammation on atherosclerotic disease progression was analyzed.	25898891
Airway structure, Asthma, Allergy - Charge Type Reason	Altered Intercellular Communication	In our group of children with asthma, no correlation was found between the level of vitamin D and the degree of airway reactivity, airway inflammation, and allergy.	25899478
Inflammation	Altered Intercellular Communication	In a relatively small cohort of clinically stable MHD patients, the veterans showed equivalent nutrition status and dietary intake and less inflammation than the nonveterans, thus not supporting the possibility that veteran MHD patients may have worse nutrition than the nonveteran counterpart.	25899538
Inflammation	Altered Intercellular Communication	Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are two new inflammatory markers used in the assessment of systemic inflammation.	25900081
Inflammation, osteoclast activating factor	Altered Intercellular Communication	Elevated CRP levels, indicating profound inflammation, may be associated with significantly increased risk of POAF in patients with CAD who underwent coronary artery bypass graft.	25901664
Inflammation	Altered Intercellular Communication	Thus, these results provide an additional line of evidence that IWT is advantageous in promoting health from an epigenetic perspective by ameliorating susceptibility to inflammation.	25901949
Inflammatory Bowel Diseases, Acute and chronic inflammation	Altered Intercellular Communication	Monocyte and M1 Macrophage-induced Barrier Defect Contributes to Chronic Intestinal Inflammation in IBD.	25901973
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Lamina propria monocytes and M1 macrophages invading intestinal tissues directly contribute to disrupting the epithelial barrier through deregulation of tight junction proteins and induction of epithelial cell apoptosis, thus driving intestinal inflammation in IBD.	25901973
Inflammation, Asthma	Altered Intercellular Communication	Definition of the overlap syndrome was based on the coexistence of post-bronchodilation FEV1/FVC < 70% and, either, an asthmatic history before the age of 40, or, at least, two functional and immune-inflammatory asthmatic traits : 1) significant FEV1 reversibility to inhaled bronchodilator (FEVI change >/= 200 ml and >/= 12% after bronchodilation), 2) eosinophilic inflammation : sputum eosinophils >= 3%,blood eosinophils >= 400/ml, or FENO >= 45 ppb, 3) clinical history of airway allergy, or total serum IgE >= 113 KU/l, or RAST >= 0,35 KU/l against major aeroallergens.	25902605
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk.	25902778
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	The role of inflammation in coronary artery disease (CAD) pathogenesis is well recognized.	25902778
Inflammation, Atherosclerosis	Altered Intercellular Communication	Multivariate analysis showed an increase in the EPA/AA ratio, but not in the DHA/AA ratio, was associated with effects on atherosclerosis-related markers, especially triglyceride-rich lipoproteins, high-density lipoprotein cholesterol (HDL-C) containing apolipoprotein A-1, and leukocyte count in an anti-atherogenic direction.The results suggest a higher EPA/AA ratio, but not a higher DHA/AA ratio, might be associated with a lower prevalence of CAD and improvements of triglyceride metabolism and HDL metabolism, and systemic inflammation.	25902881
Inflammation, Adenoma, Serrated Nodule, Colorectal Carcinoma	Altered Intercellular Communication	The candidate markers were analyzed in colonic tissue specimens from patients with colorectal cancer (n = 15), adenomas (n = 76), serrated lesions (n = 13), chronic inflammation (n = 10) and normal mucosal samples (n = 9).	25902909
Malignant tumor of colon	Altered Intercellular Communication	The methylation markers ITGA4 and TFPI2 seem to be suitable risk markers for inflammation-associated colon cancer.	25902909
Cholecystitis, Acute Cholecystitis	Altered Intercellular Communication	Is gallbladder inflammation more severe in male patients presenting with acute cholecystitis?	25903474
Cholecystitis	Altered Intercellular Communication	The extent of gallbladder inflammation has been shown to influence surgical outcome.	25903474
Cholecystitis, Acute Cholecystitis	Altered Intercellular Communication	The aim of this study was to investigate whether or not gallbladder inflammation is more severe in male patients presenting with acute cholecystitis.	25903474
Cholecystitis, Gangrene	Altered Intercellular Communication	Severe gallbladder inflammation (gangrenous and necrotizing cholecystitis) was seen in a significant portion of the male population compared to the female population (p = 0.002).	25903474
Cholecystitis	Altered Intercellular Communication	The male gender is a risk factor for severe gallbladder inflammation.	25903474
Degenerative polyarthritis, Inflammation, Disease	Altered Intercellular Communication	The Cx43 protein is overexpressed in several human diseases and inflammation processes and in articular cartilage from patients with osteoarthritis (OA).	25903580
Refractory anemias, Inflammation	Altered Intercellular Communication	These data from a large unselected population suggest that elevated RDW levels in RA patients should prompt physicians to aggressively screen and treat their patients for modifiable cardiovascular (CVS) risk factors, in addition to treating RA inflammation.	25903822
Sepsis, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD) and systemic inflammation are risk factors for sepsis.	25903849
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	While often viewed as a marker of chronic kidney disease, Cystatin C (Cyst-C) may also reflect systemic inflammation.	25903849
Epithelial Damage, Inflammation, Hypoxia	Altered Intercellular Communication	In a murine model of intratracheal lipopolysaccharide challenge, dietary-induced vitamin D deficiency resulted in exaggerated alveolar inflammation, epithelial damage and hypoxia.	25903964
Disability, Inflammation	Altered Intercellular Communication	although recent studies have suggested that inflammation may play an important role in the process of ageing and in the development of disabilities, knowledge about the role of inflammation in physical performance decline among middle-aged and older people in the context of developing countries is limited.	25904444
Inflammation	Altered Intercellular Communication	Cyclic pressurization of segmentally stiffened aortic segments ex vivo increases the expression of genes related to inflammation and extracellular matrix remodeling.	25904646
Inflammation, Glioblastoma Multiforme Pathway	Altered Intercellular Communication	Polymorphisms in inflammation, DNA repair, and metabolism pathways are associated with neurocognitive function in glioma patients and may affect clinical outcomes.	25904748
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Impact of a low-glucose peritoneal dialysis regimen on fibrosis and inflammation biomarkers.	25904773
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The impact of a low-glucose peritoneal dialysis (PD) regimen on biomarkers of peritoneal inflammation, fibrosis and membrane integrity remains to be investigated.	25904773
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Disruption of Sirtuin 1-Mediated Control of Circadian Molecular Clock and Inflammation in Chronic Obstructive Pulmonary Disease.	25905433
ARCN1 gene, Cessation of life, Chronic Obstructive Airway Disease, Abnormal inflammatory response	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is the fourth most common cause of death, and it is characterized by abnormal inflammation and lung function decline.	25905433
Hypogonadism, AVP gene, Meibomian gland dysfunction	Altered Intercellular Communication	The most common hormonal dysfunctions were diabetes insipidus (n = 7) and hypogonadism (n = 7).	25906106
Hyperglycemia, Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Association of stroke clinical outcomes with coexistence of hyperglycemia and biomarkers of inflammation.	25906929
Hyperglycemia, Inflammation, Ischemic stroke	Altered Intercellular Communication	To investigate the association of short-term clinical outcomes with coexistence of hyperglycemia and elevated biomarkers of inflammation among acute ischemic stroke (AIS) patients.	25906929
Hyperglycemia, Inflammation	Altered Intercellular Communication	This study indicated that hyperglycemia and elevated biomarkers of inflammation were associated with short-term clinical outcomes, and individuals with coexistence of hyperglycemia and elevated biomarkers of inflammation had higher risk of poor clinical outcomes among AIS patients.	25906929
Inflammation, Observation Method - Coagulation, Atherosclerosis, myocardial injury	Altered Intercellular Communication	In this population-based cohort, variables obtained by CV imaging and biomarkers of inflammation, coagulation, atherosclerosis, myocardial injury and stress, and cardiac collagen turnover were associated with YAL, an important outcome that integrates physical ability and longevity in older persons.	25907126
Inflammation	Altered Intercellular Communication	TL1A is a TNF-like cytokine which has been shown to co-stimulate TH1 and TH17 responses during chronic inflammation.	25908025
Inflammation, Carcinogenesis	Altered Intercellular Communication	Biologic activities of functional mediators activate downstream transducers regulating inflammation and carcinogenesis.	25908103
Inflammation, Malignant Neoplasms, Obesity	Altered Intercellular Communication	Obesity and vitamin D deficiency are associated with risk for several cancers, possibly through inflammation and adipokine-related pathways.	25908506
Inflammation, Arthritis	Altered Intercellular Communication	Magnetic resonance imaging (MRI) is useful for detecting joint inflammation and damage in the inflammatory arthropathies.	25908527
Cartilage damage, Gout, Refractory anemias, Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	This study aimed to investigate MRI cartilage damage and its associations with joint inflammation in patients with gout compared with a group with rheumatoid arthritis (RA).	25908527
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	The high incidence of cardiovascular disease (CVD) in chronic kidney disease (CKD) is related partially to chronic inflammation.	25908532
Inflammation	Altered Intercellular Communication	Specialized Proresolving Lipid Mediators (SPMs) derived from the n-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) actively promote the resolution of inflammation.	25908532
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	This may have important implications for limiting ongoing low grade inflammation in CKD.	25908532
Tumor necrosis, Inflammation, Deterioration	Altered Intercellular Communication	There is a direct relationship between valve deterioration and the patient's inflammatory status and cytokines: interleukin-6, interleukin-1, tumor necrosis factor, and C-reactive protein, involved in this major state of inflammation.	25909210
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Association between Inflammation and Cardiac Geometry in Chronic Kidney Disease: Findings from the CRIC Study.	25909952
Granulomatous inflammation, Granulomatosis with polyangiitis, Systemic disease, Necrotizing vasculitis	Altered Intercellular Communication	Wegener's granulomatosis (WG) is a multisystemic disease of unknown etiology characterized by necrotizing vasculitis and granulomatous inflammation.	25910303
Inflammation, Actual blood loss, Kidney Failure, Acute	Altered Intercellular Communication	The first CPB haematocrit was independently associated with AKI in the MCPB group (Relative Risk [RR]=0.484, 95% Confidence Interval [CI]=0.268-0.876, p=0.016); post-operative blood loss and inflammation were independently associated with AKI in the CCPB group (RR=1.005, 95%CI=1.003-1.007, p<0.001; RR=1.018, 95%CI=1.010-1.028, p<0.001).	25910838
Discordance, Inflammation	Altered Intercellular Communication	Discordance (LDL-PNMR > apoB) was associated with insulin resistance, smaller LDL particle size, increased systemic inflammation, and low circulating levels of "traditional" lipids, whereas discordance (apoB > LDL-PNMR) was associated with larger LDL particle size, and elevated levels of lipoprotein(a) and lipoprotein-associated phospholipase A2 (Lp-PLA2).	25911082
Inflammation, Cystic Fibrosis	Altered Intercellular Communication	Heart involvement in children and adults with cystic fibrosis: correlation with pulmonary indexes and inflammation markers.	25911142
Renal Insufficiency, Inflammation, Respiratory physiology	Altered Intercellular Communication	We hypothesise that such cardiac impairments may gradually arise due to preceding chronic inflammation related to prior degeneration of lung function and thus it is very important to keep patients clinically stable and address chronic inflammation as early as possible in the progression of CF.	25911142
Inflammation	Altered Intercellular Communication	Joint inflammation detected at extremity MRI was the secondary outcome.	25911456
MTTP wt Allele	Altered Intercellular Communication	With MRI-detected inflammation as outcome, the sensitivity and specificity were 39% and 86% and 31% and 69% for the test at the MCP and MTP joints, respectively.	25911456
Inflammation	Altered Intercellular Communication	A positive squeeze test is associated with local joint inflammation but the sensitivity is low, indicating a high percentage of swollen joints with a negative squeeze test.	25911456
Inflammation, Nasopharyngeal carcinoma	Altered Intercellular Communication	Increasing evidences suggest that NO promotes inflammation induced growth of nasopharyngeal carcinoma (NPC).	25912222
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	We investigated established diabetes biomarkers that could implicate potential mechanistic pathways, including C-reactive protein (CRP), a marker of systemic inflammation; gamma glutamyl transferase (GGT), a liver enzyme associated with oxidative stress; and adiponectin, an adipokine modulating glucose regulation and fatty acid oxidation.	25913152
Inflammation, Thrombosis, atherosclerotic	Altered Intercellular Communication	p38MAPK is an important element of inflammatory pathways in atherothrombosis and its inhibition may lead to reduced inflammation within atherosclerotic plaques.	25913664
Inflammatory Bowel Diseases, Inflammation, Carcinoma	Altered Intercellular Communication	Our data demonstrate a high rate of pre-operatively undetected high-grade IENs and carcinoma and a frequent multifocal occurrence in IBD patients with long-standing inflammation of the colon.	25913799
Gingivitis, Dental Plaque	Altered Intercellular Communication	Performance of a light fluorescence device for the detection of microbial plaque and gingival inflammation.	25914048
Gingivitis, Dental Plaque	Altered Intercellular Communication	The SOPROCARE fluorescence tool in perio-mode provides reliable evaluation of microbial plaque and gingival inflammation for the dental clinician.	25914048
Inflammation, Liver carcinoma, Liver Cirrhosis, Liver Failure	Altered Intercellular Communication	The final sequalae of cirrhosis, liver failure and hepatocellular carcinoma are often the result of inflammation driven by intrahepatic lymphocytes.	25914090
Orchitis	Altered Intercellular Communication	Nineteen proteins were altered by nicotine in the model of articular inflammation, including several cytokines and proteases.	25914226
Inflammation, Breast Carcinoma, Pain Distress Question	Altered Intercellular Communication	Consequently, the purpose of our work is to identify some biochemical parameters involved in the events cascade associated with inflammation and pain in breast cancer female patients, monitored in dynamics of anesthesia and surgical procedure.	25914735
Eyelid Diseases, Inflammatory abnormality of the eye, Dryness (characteristic), Ocular Surface Disease Index, Eyelid Neoplasms	Altered Intercellular Communication	Common ophthalmological problems are found in patients with eyelid tumors and include ocular surface diseases, such as dry eyes, eyelid disorders, excessive tearing and ocular inflammation.	25914748
Colonic Polyps	Altered Intercellular Communication	Low Prevalence of Colon Polyps in Chronic Inflammatory Conditions of the Colon.	25916222
Colonic Polyps	Altered Intercellular Communication	Chronic inflammatory conditions of the colon are associated with a decreased prevalence of colon polyps.	25916222
Inflammation	Altered Intercellular Communication	The histological analysis demonstrated low to moderate inflammation, displaying areas of inflammatory infiltrate in the bone marrow.	25916730
Sample Size Calculation, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Systemic sclerosis (SSc) is characterized by chronic inflammation and fibrosis.	25917089
Inflammation, N-Formylmethionine	Altered Intercellular Communication	N-Formyl peptide (fMLF) receptors (FPRs) are chemotactic receptors involved in inflammation.	25917089
Inflammation, Acute inflammation, prostatitis	Altered Intercellular Communication	The number of IELs in both around and inside inflammation areas correlated to the grade and location of HP (P < 0.0001 and P < 0.0003), the presence of acute glandular inflammation (P < 0.0001), the scattered stromal lymphocytes (P = 0.029), and BPH and PIN associated prostatic inflammation (P < 0.0001).	25917232
Inflammation, Asthma	Altered Intercellular Communication	Exhaled breath temperature (EBT) reflects airways (both eosinophilic and neutrophilic) inflammation in asthma and thus may aid the management of children with asthma that are treated with anti-inflammatory drugs.	25917297
Airway structure	Altered Intercellular Communication	A new EBT monitor has become available that is cheap and easy to use and may be a suitable monitoring device for airways inflammation.	25917297
Airway structure, Asthma	Altered Intercellular Communication	Little is known about how EBT relates to asthma treatment decisions, disease control, lung function, or other non-invasive measures of airways inflammation, such as exhaled nitric oxide (ENO).	25917297
Inflammation, Carcinoma of lung	Altered Intercellular Communication	The present findings add to the evidence implicating inflammation in lung cancer etiology.	25917613
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Leucine-rich a2 -glycoprotein as a potential biomarker for joint inflammation during anti-interleukin-6 biologic therapy in rheumatoid arthritis.	25917892
Refractory anemias, Inflammation, Arthritis	Altered Intercellular Communication	Under conditions of IL-6 inhibition, LRG was more useful than other biomarkers in discriminating between active and inactive disease in human RA and in detecting joint inflammation in experimental arthritis.	25917892
Inflammation, Encrusted cystitis, Bacterial Infections, Corynebacterium	Altered Intercellular Communication	Encrusted cystitis is a rare condition characterized by encrustation of the bladder mucosa with associated chronic inflammation induced by urea-splitting bacterial infection--most commonly, Corynebacterium urealyticum.	25918192
Hepatitis, Chronic, Hepatocarcinogenesis	Altered Intercellular Communication	Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis.	25918251
Liver carcinoma, Hepatitis, Chronic, FAM126A gene	Altered Intercellular Communication	Chronic liver inflammation precedes the majority of hepatocellular carcinomas (HCC).	25918251
Inflammation, FAM126A gene	Altered Intercellular Communication	Here, we explore the connection between chronic inflammation and DNA methylation in the liver at the late precancerous stages of HCC development in Mdr2(-/-) (Mdr2/Abcb4-knockout) mice, a model of inflammation-mediated HCC.	25918251
Inflammation	Altered Intercellular Communication	Chronic inflammation did not change global levels of DNA methylation in Mdr2(-/-) liver, but caused a 2-fold decrease of the global 5-hydroxymethylcytosine level in mutants compared to controls.	25918251
Hepatitis, Chronic	Altered Intercellular Communication	Our findings demonstrate that chronic liver inflammation causes hypermethylation of specific CGIs, which may affect both hepatocytes and non-hepatocyte liver cells.	25918251
Hyperparathyroidism, Structure of thick cushion of skin on foot	Altered Intercellular Communication	Neither hyperparathyroidism nor inflammation malnutrition syndrome was found to contribute to the formation of oral tori in chronic hemodialysis patients.	25918724
Communicable Diseases, Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation is considered an immune mechanism against infection or certain non-neoplastic conditions.	25918980
Inflammation, Corneal Endothelial Cell Loss	Altered Intercellular Communication	Activated leukocytes may produce free oxygen radicals and endothelial damage, and, thereby, increased inflammation and thrombogenesis.	25919135
Reduction mammaplasty, Inflammation, Pain, Postoperative	Altered Intercellular Communication	Pulsed electromagnetic fields have been shown to reduce postoperative pain, inflammation, and narcotic requirements after breast reduction and augmentation surgical procedures.	25919263
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding, Heart failure	Altered Intercellular Communication	There is mounting evidence to support the influence of inflammation and oxidative stress in the pathogenesis of atrial fibrillation (AF) and heart failure (HF).	25919281
Inflammation, Complications of Diabetes Mellitus, Diabetes Mellitus	Altered Intercellular Communication	Chronic inflammation from diabetes mellitus effects glycemic control and increases risk of diabetes complications.	25920299
Inflammation, Fibrosis Assessment, Edema	Altered Intercellular Communication	Fibroblast proliferation, fibrosis, perivascular inflammation, oedema, vascular proliferation and vascular wall thickness were determined and scored in all specimens.	25920601
Inflammation, Fibrosis Assessment, Hyperplasia, Tenosynovitis	Altered Intercellular Communication	Synovial hyperplasia, fibrosis and perivascular inflammation were not observed in tenosynovial analysis of both groups.	25920601
Inflammation, Fibrosis Assessment, Edema	Altered Intercellular Communication	There was no oedema, fibrosis and perivascular inflammation of the epineurium in specimens of either group.	25920601
Inflammation, Interneurons, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	Localised selective GABAergic interneuron loss in layers IV and VI was related to GMLs but was not explained by the presence of inflammation or by mitochondrial dysfunction within Type I GMLs.	25921040
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Chronic inflammation could affect the occurrence and development of malignant tumors.	25921150
Small cell carcinoma of lung, Primary malignant neoplasm	Altered Intercellular Communication	Advanced Lung Cancer Inflammation Index, a New Prognostic Score, Predicts Outcome in Patients With Small-Cell Lung Cancer.	25922292
Acute Lung Injury, Primary malignant neoplasm, Small cell carcinoma of lung	Altered Intercellular Communication	This report is the first to use the value of the Advanced Lung Cancer Inflammation Index (ALI) to predict the overall survival in patients with small-cell lung cancer.	25922292
Acute Lung Injury, Primary malignant neoplasm, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	A recent study indicated that the Advanced Lung Cancer Inflammation Index (ALI) could predict overall survival (OS) in patients with non-small-cell lung cancer.	25922292
Inflammation, Plasma/serum xenobiotic	Altered Intercellular Communication	Plasma/serum levels of several biomarkers of inflammation and oxidative stress and nitrite/nitrate were assessed upon admission and 24 h after STEMI onset in patients treated by primary percutaneous coronary intervention.	25922551
Inflammation, Macular edema due to diabetes mellitus	Altered Intercellular Communication	A variety of cytokines associated with inflammation and angiogenesis may contribute to the pathogenesis of diabetic macular edema, and both anti-inflammatory and antiangiogenic agents should be included in the treatment of ME simultaneously.	25923230
Cholesteatoma, Inflammation	Altered Intercellular Communication	Postoperatively, cholesteatoma samples were analyzed by immunostaining for MPO positivity as a marker for acute inflammation.	25923274
Inflammation	Altered Intercellular Communication	Transcription factor Kruppel-like factor 6 (KLF6)-myeloid-specific conditional deficient mice exhibit this aortic phenotype when subjected to aortic inflammation.	25923510
Pancreatic calcification, Inflammation, Pancreas, Diabetes Mellitus	Altered Intercellular Communication	Fibrocalculous Pancreatic Diabetes is a unique entity wherein pancreatic calcification and chronic inflammation lead to exocrine and endocrine failure of the pancreas.	25924662
Acute Q fever, Chronic Q Fever, Fever, CTCAE	Altered Intercellular Communication	To identify the immune mechanisms responsible for ineffective clearance of Coxiella burnetii in patients who developed chronic Q fever, we compared serum concentrations of 47 inflammation-associated markers among patients with acute Q fever, vascular chronic Q fever, and past resolved Q fever.	25924761
Inflammation, Angina Pectoris, Electrocardiogram: myocardial infarction (finding), Dyslipidemias, atherosclerotic	Altered Intercellular Communication	Inflammation and dyslipidaemia may play an important role in the development of atherosclerotic complications, for example myocardial infarction and angina pectoris.	25924966
HD Term Type, Inflammation	Altered Intercellular Communication	PTX3 may be considered a novel biomarker of inflammation in HD patients.	25924996
vascular inflammations, Depression, CTCAE, Cardiomyopathies	Altered Intercellular Communication	However, patients with more frequent wine consumption had a significantly better perception of health status (Kansas City Cardiomyopathy Questionnaire score, adjusted P<0.0001), less frequent symptoms of depression (Geriatric Depression Scale, adjusted P=0.01), and lower plasma levels of biomarkers of vascular inflammation (osteoprotegerin and C-terminal proendothelin-1, adjusted P<0.0001, and pentraxin-3, P=0.01) after adjusting for possible confounders.	25925415
vascular inflammations, Chronic heart failure, Depression, CTCAE	Altered Intercellular Communication	We show for the first time in a large cohort of patients with chronic heart failure that moderate wine consumption is associated with a better perceived and objective health status, lower prevalence of depression, and less vascular inflammation, but does not translate into more favorable clinical 4-year outcomes.	25925415
Inflammation	Altered Intercellular Communication	Nuclear enzyme poly(ADP-ribose) polymerase 1 (PARP-1) is associated with inflammation response.	25926140
Inflammation	Altered Intercellular Communication	These data suggested that PARP-1 inhibition prevents IL-1b-induced inflammation response at least partly by inhibiting the IL-1R/NF-kB signaling pathway in human articular chondrocytes.	25926140
Prostate carcinoma	Altered Intercellular Communication	Association between Serum Phospholipid Fatty Acids and Intraprostatic Inflammation in the Placebo Arm of the Prostate Cancer Prevention Trial.	25926387
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Inflammation may play an etiologic role in prostate cancer.	25926387
Degenerative polyarthritis, Arthritis	Altered Intercellular Communication	The purpose of this study was to evaluate synovial fluid from knees with and without OA for potential markers of joint inflammation and degradation and to correlate these findings with radiographic severity of disease.	25927354
Inflammation, animal organ regeneration	Altered Intercellular Communication	Specifically, the aged mice showed systemic inflammation and organ degeneration.	25927599
Inflammation, Degenerative disorder	Altered Intercellular Communication	These findings showed for the first time that arginine 213 in the HBD of SOD3 is critical for maintaining proper organ function through moderating the normal innate immune response, which would otherwise lead to chronic inflammation and degenerative diseases in aged mice.	25927599
Degenerative polyarthritis, Inflammation, Facet joint structure	Altered Intercellular Communication	In this study we conducted an in situ analysis of IL-6 expression at different sites of inflammation in zygapophyseal joints of patients with AS in comparison to osteoarthritis autopsy controls (CO).	25928402
Inflammation	Altered Intercellular Communication	The relevance of pro-inflammatory agents in axial SpA might be studied better in situ in bony specimens at the primary site of inflammation.	25928402
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	The expression of Th1-specific cytokines, known to be associated with autoimmune inflammation (i.e.	25928531
Limbic Encephalitis, Inflammation, Immune-mediated	Altered Intercellular Communication	Limbic encephalitis, an immune-mediated encephalitis, results from inflammation in the medial temporal lobes.	25929634
Inflammation, Intracranial Aneurysm, Rupture, Aneurysm	Altered Intercellular Communication	Inflammation and degeneration of the intracranial saccular aneurysm wall play a major role in aneurysm formation, development and subsequent rupture.	25929881
Inflammation	Altered Intercellular Communication	TLR4 gene polymorphism may take part in the development of chronic inflammation in women after menopause, which is the cause of severe bone resorption.	25931355
Chronic kidney disease stage 5, Inflammation, Kidney Failure, Chronic, Immunologic Deficiency Syndromes	Altered Intercellular Communication	Patients with end stage renal disease (ESRD) suffer from chronic inflammation, leading to a secondary, uremic immunodeficiency associated with alterations in monocyte subpopulations with increased proinflammatory capacities.	25931358
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	This indicates that chronic inflammation may substantiate the biased consistence of monocyte subpopulations leading to profound alteration in DC generation and maturation in ESRD.	25931358
Chronic abscess, hormone deficiency	Altered Intercellular Communication	A chronic abscess state may be the most important factor associated with permanent hormone deficiency.	25932567
Inflammation, Malnutrition, Pellagra, Flaky paint dermatosis	Altered Intercellular Communication	In this case series we provide evidence that malnourished patients with flaky paint dermatosis and infection/inflammation shown laboratory data suggestive of indoleamine 2,3-dioxygenase (IDO) activation, besides decreased urinary excretion of N1-methylnicotinamide (N1 MN), a marker of pellagra.	25933499
Communicable Diseases, Inflammation, Flaky paint dermatosis	Altered Intercellular Communication	We study nine adult patients showing flaky paint dermatosis and clinical features of infection or inflammation, and increased serum C-reactive protein, characteristic of the presence of acute phase response syndrome.	25933499
Cerebellar Diseases	Altered Intercellular Communication	The alteration in GABAA receptor-dependent neurotransmission is a potential mechanism for ethanol-induced cerebellar dysfunction.	25933648
Inflammation, Hypertension, CTCAE, Cardiovascular Diseases	Altered Intercellular Communication	Hypertension and inflammation may contribute to the increased risk of cardiovascular disease in individuals with suboptimal sleep, but large prospective studies are lacking.	25934538
Squamous cell carcinoma of esophagus	Altered Intercellular Communication	A novel inflammation-based prognostic score in esophageal squamous cell carcinoma: the C-reactive protein/albumin ratio.	25934640
Primary malignant neoplasm	Altered Intercellular Communication	Plenty of studies have demonstrated the prognostic value of various inflammation-based indexes in cancer.	25934640
Squamous cell carcinoma of esophagus	Altered Intercellular Communication	The CRP/Alb ratio is a novel but promising inflammation-based prognostic score in esophageal squamous cell carcinoma.	25934640
Airway structure, Asthma	Altered Intercellular Communication	Future studies should investigate the impact of exercise intensity and exercise training on airway inflammation in those with asthma.	25935433
Inflammation, Cardiac sarcoidosis	Altered Intercellular Communication	Inflammation and oxidative stress play a crucial role in the pathogenesis of cardiac sarcoidosis (SAR).	25935620
Vasculitis, Leukocytoclastic, Cutaneous	Altered Intercellular Communication	Cutaneous small vessel vasculitis is a severe neutrophilic vascular inflammation mediated by immune complexes that involves the dermal postcapillary venules.	25935914
Pyelonephritis, Chronic inflammation, Obstruction, Kidney Diseases, Kidney Calculi	Altered Intercellular Communication	Xanthogranulomatous pyelonephritis is an uncommon disorder of the kidney that is characterised by chronic inflammation and extensive destruction of the involved kidney usually associated with renal calculus and obstruction.	25935947
Inflammation, Arthritis, Psoriasis, Skin lesion	Altered Intercellular Communication	In conclusion, H2 administration reduced inflammation associated with psoriasis in the three cases examined and it may therefore be considered as a treatment strategy for psoriasis-associated skin lesions and arthritis.	25936373
Heart Diseases, Inflammation	Altered Intercellular Communication	The aim of this study was a prospective evaluation of the inflammation parameters in patients with different forms of AF without structural heart disease.	25936571
Inflammation, Left Bundle-Branch Block, Myocardial	Altered Intercellular Communication	Of 92 patients, 34 developed LBBB without more advanced myocardial damage or inflammation biomarkers in comparison with patients without LBBB.	25937352
Inflammation, Left Bundle-Branch Block, Myocardial	Altered Intercellular Communication	In conclusion, after TAVI, 37% of patients developed new LBBB without more advanced myocardial damage or inflammation biomarkers.	25937352
vascular inflammations, Muscle, Smooth, Vascular	Altered Intercellular Communication	SM22a inhibits vascular inflammation via stabilization of IkBa in vascular smooth muscle cells.	25937534
Vascular Diseases	Altered Intercellular Communication	SM22a may be a novel therapeutic target for human vascular diseases and other inflammatory conditions.	25937534
Airway structure, ARCN1 gene	Altered Intercellular Communication	These longitudinal changes may be due to increasing airway inflammation or to progression of COPD.	25938279
Inflammation, Electrocardiogram: myocardial infarction (finding), Aortic Valve Stenosis	Altered Intercellular Communication	Elevated Lipoprotein(a) Does Not Cause Low-Grade Inflammation Despite Causal Association With Aortic Valve Stenosis and Myocardial Infarction: A Study of 100,578 Individuals from the General Population.	25938632
Inflammation, Electrocardiogram: myocardial infarction (finding), Aortic Valve Stenosis	Altered Intercellular Communication	We tested the hypothesis that elevated lipoprotein(a) is observationally and causally associated with low-grade inflammation together with aortic valve stenosis and myocardial infarction.	25938632
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	Elevated levels of lipoprotein(a) were not causally associated with increased low-grade inflammation as measured through CRP despite a causal association with increased risk of aortic valve stenosis and MI.	25938632
Inflammation, Intestinal Microbiome	Altered Intercellular Communication	The current model for disease suggests that genetically susceptible patients develop intolerance to gut microflora, and chronic inflammation develops as a result of environmental insults.	25939040
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Intraprostatic inflammation is positively associated with serum PSA in men with PSA <4 ng ml(-1), normal DRE and negative for prostate cancer.	25939516
Inflammation, Prostate carcinoma	Altered Intercellular Communication	However, the influence of intraprostatic inflammation on serum PSA in men without biopsy indication and negative for prostate cancer has not been described in detail.	25939516
Inflammation	Altered Intercellular Communication	Median percentage of tissue area with inflammation increased from 2 to 5 to 9.5% across PSA tertiles (P-trend <0.0001).	25939516
Inflammation	Altered Intercellular Communication	Median extent and intensity scores increased across PSA tertiles in luminal and intraepithelial compartments for acute inflammation and in stromal and intraepithelial compartments for chronic inflammation (all P-trend <=0.05).	25939516
Inflammation, Prostate carcinoma	Altered Intercellular Communication	In men without clinical suspicion of prostate cancer, greater overall inflammation, luminal and intraepithelial acute inflammation and stromal and intraepithelial chronic inflammation were associated with higher serum PSA.	25939516
Lesion Restenosis Indicator, Inflammation	Altered Intercellular Communication	On histopathology, the restenosis lesion at the SES-deployed site showed greater inflammation and less re-endothelialization than that at the BMS-deployed site.	25939630
Inflammation, Atherosclerosis	Altered Intercellular Communication	Drug-eluting stents still have problems of persistent inflammation, inappropriate neointima formation, and neoatherosclerosis.	25939630
Inflammation, Cardiac valve calcification, Malnutrition, Atherosclerosis	Altered Intercellular Communication	Periaortic Fat Tissue: A Predictor of Cardiac Valvular Calcification, Malnutrition, Inflammation, and Atherosclerosis Components in Hemodialysis Patients.	25940595
Kidney Failure, Chronic, Inflammation, Cardiac valve calcification, Malnutrition, Atherosclerosis, Calcinosis	Altered Intercellular Communication	Cardiac valvular calcification (CVC) in end-stage renal disease is shown to be a component of malnutrition, inflammation, atherosclerosis, calcification (MIAC) syndrome.	25940595
HD Term Type, Inflammation	Altered Intercellular Communication	In this study, T-PAFT showed a positive correlation with inflammation, CVC, and MIAC score in HD patients.	25940595
Inflammation, Rosacea	Altered Intercellular Communication	Recombinant erythroid differentiation regulator 1 inhibits both inflammation and angiogenesis in a mouse model of rosacea.	25940661
Abnormal inflammatory response, Hyperactive behavior, Rosacea, Inflammatory disorder	Altered Intercellular Communication	Rosacea is a chronic inflammatory skin disorder that is characterized by abnormal inflammation and vascular hyperactivity of the facial skin.	25940661
Inflammation, Erythema, Telangiectasis	Altered Intercellular Communication	LL-37 injection induced typical rosacea features, including erythema, telangiectasia and inflammation.	25940661
Inflammation, Rosacea	Altered Intercellular Communication	Taken together, our findings suggest that rErdr1 may be involved in attenuating the inflammation and angiogenesis associated with the pathogenesis of rosacea.	25940661
Inflammation, Lymphocytic infiltration, Necrosis, Osteolysis	Altered Intercellular Communication	These tribocorrosion-related tissue reactions are characterized by marked necrosis and lymphocytic infiltration, which contrasts sharply with the macrophagic and foreign body giant cell inflammation associated with polyethylene wear particle induced peri-implant osteolysis.	25940887
Inflammation, Cutaneous, Lupus Erythematosus	Altered Intercellular Communication	They also develop spontaneous skin inflammation similar to the cutaneous lesions common in human lupus erythematosus.	25941899
Proteinuria, Glomerular filtration, Nephritis	Altered Intercellular Communication	The Y group showed the greatest decrease in anti-dsDNA antibodies, organ weight, degree of kidney inflammation and glomerular infiltration of C3, and incidence rate of severe proteinuria; the E, L, and CT treatment groups showed better results than the C group.	25941899
Inflammation, Sensitization (observable entity)	Altered Intercellular Communication	The beryllium bronchoalveolar lavage lymphocyte proliferation test: indicator of beryllium sensitization, inflammation or both?	25942054
Pneumonitis, Sensitization (observable entity)	Altered Intercellular Communication	The objective was to describe the contribution of the BeBALLPT to classification of workers with respect to beryllium sensitization (BeS) and beryllium-induced lung inflammation.	25942054
Granulomatous inflammation	Altered Intercellular Communication	We analyzed factors influencing BeBALLPT outcome, and its relation to blood-determined BeS and granulomatous inflammation.	25942054
Pneumonitis	Altered Intercellular Communication	Positive BeBALLPTs contributed evidence of BeS in subjects without prior positive beryllium blood lymphocyte proliferation tests (BeBLPTs) and of pulmonary inflammation in persons without granulomata evident on lung biopsy.	25942054
Granuloma, Pneumonitis	Altered Intercellular Communication	A positive BeBALLPT is closely linked to the presence of granulomata on lung biopsy and can be considered as an indicator of lung inflammation in addition to BeS.	25942054
Pneumonitis	Altered Intercellular Communication	It is not recommended that a positive BeBALLPT be considered sufficient evidence for both lung inflammation and BeS.	25942054
ARCN1 gene, Inflammation	Altered Intercellular Communication	Heightened inflammation, including expression of COX-2, is associated with COPD pathogenesis.	25943190
ARCN1 gene, Inflammation	Altered Intercellular Communication	Our data indicate that RelB attenuates COX-2 expression in lung structural cells, such that loss of pulmonary RelB may be an important determinant in the aberrant, heightened inflammation associated with COPD pathogenesis.	25943190
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Furthermore, we found a clear correlation between stromal caspase-4 and -5 expression levels, inflammation and disease activity in ulcerative colitis patients.	25943872
Inflammatory Bowel Diseases, Colorectal Carcinoma, Gastrointestinal inflammation	Altered Intercellular Communication	Deregulated intestinal inflammation in IBD patients is associated with an increased risk of developing CRC.	25943872
Proteinuria, Cardiac fibrosis, Nephritis, Tumor necrosis, Glomerulosclerosis (disorder)	Altered Intercellular Communication	This fluid retention was associated with an increase in blood pressure, proteinuria, renal inflammation with macrophage infiltration and tumor necrosis factor-a overexpression, glomerular sclerosis, and cardiac fibrosis.	25944876
Inflammation, Neoplasms	Altered Intercellular Communication	GROb (CXCL2) is a chemokine produced by endotoxin-treated macrophages that mediates inflammation and tumor development.	25944970
Inflammation, Atrophic	Altered Intercellular Communication	On the other hand, normal mucosa was defined as mucosa not demonstrating histological abnormalities, including inflammation and atrophy.	25945015
Inflammation, Burn injury	Altered Intercellular Communication	Matrix metalloproteinases (MMPs) -8 and -9 are released from neutrophils in acute inflammation and may contribute to permeability changes in burn injury.	25945788
Inflammation, Atherosclerosis	Altered Intercellular Communication	NLRP3 is involved in inflammation that leads to atherosclerosis.	25946654
Data types - Address	Altered Intercellular Communication	Blood platelets contain the neurotransmitter serotonin and amyloid-precursor protein (APP), and may thus be useful as a peripheral biomarker for AD.	25947203
Inflammation, Pathologic Neovascularization, GDC Disease Response Terminology	Altered Intercellular Communication	Persistent inflammation and impaired neovascularisation may be important contributors to the development of DR. A recent study showed that toll-like receptor 4 (TLR4) polymorphisms were associated with DR.	25947554
IgG4-Related Sclerosing Disease, Orbital Pseudotumor	Altered Intercellular Communication	IgG4-related disease in idiopathic sclerosing orbital inflammation.	25947555
Inflammation, Rheumatoid Arthritis, Primary malignant neoplasm	Altered Intercellular Communication	What is the impact of chronic systemic inflammation such as rheumatoid arthritis on mortality following cancer?	25948597
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Emerging evidence links inflammation and immune competence to cancer progression and outcome.	25948597
Inflammation, Obesity	Altered Intercellular Communication	The environmental and behavioral risk factors associated with central obesity and/or inflammation in populations exposed to both obesogenic and pathogenic environments remain unclear.	25948781
Symptoms, Inflammation	Altered Intercellular Communication	Men with high WHtR with inflammation had higher odds of infectious symptoms than those with high WHtR without inflammation (OR: 1.73; 95% CI: 1.15, 2.61).	25948781
Gynecomastia	Altered Intercellular Communication	Hormonal work ups for gynaecomastia all turned out normal, thus isolating the drug as the cause.	25948845
Inflammation	Altered Intercellular Communication	We also determined whether baseline levels of inflammation markers and immune activation were independently associated with BMD loss.	25948863
Inflammation	Altered Intercellular Communication	Inflammation and immune activation/senescence before ART initiation independently predicted subsequent BMD loss.	25948863
ARCN1 gene	Altered Intercellular Communication	Airway IL-1b and Systemic Inflammation as Predictors of Future Exacerbation Risk in Asthma and COPD.	25950204
ARCN1 gene, Inflammation, Asthma, Exacerbation	Altered Intercellular Communication	This study aimed to investigate airway innate immune activation and systemic inflammation as predictors of exacerbations in asthma and COPD.	25950204
Airway structure, Inflammation, Exacerbation	Altered Intercellular Communication	The relationships among airway inflammation, systemic inflammation, and future exacerbations were examined using path analysis.	25950204
Inflammation, Asthma	Altered Intercellular Communication	Systemic inflammation was also associated with increased exacerbation risk in asthma.	25950204
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	Airway IL-1b and systemic inflammation are associated with frequent exacerbations and may mediate a vicious cycle between previous and future exacerbations in COPD.	25950204
Macular Edema, Cystoid, Acute inflammation	Altered Intercellular Communication	Although it is presumed to be associated with an inflammatory cascade and possible postoperative inflammation, only 2 cases of SLT complicated by cystoid macular edema have been previously reported.	25950662
Inflammation, Chronic disease	Altered Intercellular Communication	Our findings did not corroborate any anti-inflammatory effects of testosterone or corresponding potentially protective effects of testosterone on chronic diseases resulting from reduced low-grade systemic inflammation.	25950910
Inflammation, Damage	Altered Intercellular Communication	Rarefaction significantly increases peripheral resistance which results in elevated blood pressure, leads to vessel damage and induction of inflammation.	25951297
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	The hypertensive group was also characterized by elevated levels of CRP, VEGF and IL-8 that are the hallmarks of inflammation.	25951297
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Presented results show that hypertension is characterized by imbalance of pro-angiogenic and anti-angiogenic factors in the background of inflammation.	25951297
Parkinsonian Disorders	Altered Intercellular Communication	However, Parkinson pathology is more widespread in the brain, affecting also other dopaminergic pathways and neurotransmitter systems, but these changes are less well characterized.	25952735
Degenerative polyarthritis, Inflammation, Atherosclerosis	Altered Intercellular Communication	This might suggest an association between atherosclerosis and knee OA through low-grade systemic inflammation in women.	25953699
Ischemia, Observation Method - Coagulation, Inflammation, Cerebrovascular accident	Altered Intercellular Communication	BAIPC may safely inhibit stroke recurrence, protect against brain ischemia, and ameliorate plasma biomarkers of inflammation and coagulation in octo- and nonagenarians with SIAS.	25956401
Ulcerative Colitis	Altered Intercellular Communication	The Impact of Endoscopic Inflammation and Mucosal Healing on Health-related Quality of Life in Ulcerative Colitis Patients.	25956537
Inflammation, Colitis	Altered Intercellular Communication	Clinical disease activity was assessed by the Simple Clinical Colitis Activity Index [SCCAI], endoscopic inflammation by the Mayo Endoscopic Subscore [MES], and HRQoL by the Short Inflammatory Bowel Disease Questionnaire [SIBDQ] and Short Health Scale [SHS].	25956537
Inflammation	Altered Intercellular Communication	Not only clinical disease activity but also endoscopic inflammation and disease extent were associated with decreased HRQoL.	25956537
Inflammatory Bowel Diseases, Crohn Disease, Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are characterized by chronic intestinal inflammation due to immunological, microbial, and environmental factors in genetically predisposed individuals.	25956706
Inflammation	Altered Intercellular Communication	In multivariate analysis, older age (>=50 versus 30-<40 years: prevalence ratio [PR], 2.36; 95% confidence interval [CI], 1.45-3.84, p for trend = 0.001), lower CD4 + cell counts (<100 versus >=200 cells/mm(3): PR, 1.55; 95% CI, 1.01-2.36, p for trend = 0.03) and cervical inflammation (PR, 1.73; 95% CI, 1.16-2.60, p = 0.008) were associated with an increased risk of cervical SIL.	25957324
Bone Diseases, Protein-Energy Malnutrition	Altered Intercellular Communication	Changes in mineral bone disease, protein-energy wasting/inflammation, and occurrence of adverse events after 1 year.	25958079
Protein-Energy Malnutrition	Altered Intercellular Communication	There was no evidence of protein-energy wasting/inflammation or aluminum toxicity, and fewer participants randomly assigned to ferric citrate had serious adverse events.	25958079
Pharyngitis, Atlantoaxial, Syndrome, Joint Subluxations	Altered Intercellular Communication	Grisel syndrome is a nontraumatic rotatory subluxation of the atlantoaxial joint, following nasopharyngeal inflammation or ear, nose, and throat (ENT) procedures.	25959249
Necrotizing granulomatous inflammation, Propionibacterium	Altered Intercellular Communication	These findings suggest that propionibacteria might be associated with sarcoidosis granulomatous inflammation.	25959360
Arterial Stiffness, Inflammation, Endothelial dysfunction, glycation	Altered Intercellular Communication	Arterial stiffness is related to inflammation, oxidative stress, advanced glycation end products (AGEs), and endothelial dysfunction.	25959807
Gingivitis, Inflammation, Bacteremia	Altered Intercellular Communication	We hypothesized that in the development of gingival inflammation, systemic markers of inflammation and bacteremia would increase.	25960104
Inflammation	Altered Intercellular Communication	Inflammation is important for initiation and progression of the disease.	25960616
airway disease, Airway Obstruction, Airway structure	Altered Intercellular Communication	The high collapsibility in patients with predominant airway disease, mild airway obstruction, and in women with this phenotype may reflect chronic airway inflammation.	25960647
Airway structure, Smooth muscle (tissue)	Altered Intercellular Communication	We assessed airway inflammation, reticular basement membrane (RBM) thickness, airway smooth muscle (ASM), mucus gland area, vascularity, and epithelial integrity.	25961111
Inflammation, Wheezing	Altered Intercellular Communication	Airway morphometrics and inflammation were similar in viral and multiple-trigger wheezers.	25961111
Inflammation, Wheezing, MS4A2 wt Allele	Altered Intercellular Communication	In preschoolers with severe recurrent wheeze, markers of remodeling and inflammation are unrelated, and atopy is associated with ASM.	25961111
Inflammation	Altered Intercellular Communication	Albumin concentration is associated with nutrition and inflammation.	25961608
Inflammation, NCI CTEP SDC Retinoblastoma Sub-Category Terminology	Altered Intercellular Communication	Anterior inflammation is a rare form of masquerade syndrome associated with retinoblastoma; however, it tends to be associated with diffuse posterior segment retinoblastoma when it does occur.	25961779
Primary malignant neoplasm, Focal acute inflammation, Intestinal Obstruction, Obesity	Altered Intercellular Communication	There are advantages in case of obesity presence (IMT more than 30 kg/m2), in significant shortening of the mesocolon and mesentery, high fixation of splenic flexure and intimate fixation of the spleen, in case of bad preparation of the bowels in partial intestinal obstruction or in case of emergency operation, big cancer size, expressed perifocal inflammation.	25962296
Primary sclerosing cholangitis, Inflammation, Neoplasms	Altered Intercellular Communication	The risk of neoplasia was not significantly associated with the type of lesion (P = .94 from log-rank test), primary sclerosing cholangitis (P = .94), or active inflammation (P = .41) in this cohort.	25962315
Inflammation	Altered Intercellular Communication	We hypothesise that longer standing chronic inflammation and older age may cause a less prompt and effective response to treatment in SA when compared with their genetically related controls.	25962691
Inflammation	Altered Intercellular Communication	Primary outcome measures assessing joint health were serum cartilage oligomeric matrix protein (sCOMP) and knee joint synovial inflammation (Doppler ultrasound colour fraction; CF).	25962747
Inflammation, Intervertebral Disk Displacement	Altered Intercellular Communication	Markers of inflammation and fibrinolysis in relation to outcome after surgery for lumbar disc herniation.	25962814
Inflammation, Back Pain, Sciatica	Altered Intercellular Communication	The role of inflammation and fibrinolysis for the development of back pain and sciatica has been discussed.	25962814
Endothelial dysfunction, Diabetic Angiopathies, Diabetes Mellitus	Altered Intercellular Communication	Pro-inflammatory conditions induced by products of protein glycation in diabetes substantially enhance the risk of endothelial dysfunction and related vascular complications.	25963575
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Tertiary lymphoid structures (TLSs) in chronic inflammation, including rheumatoid arthritis (RA) synovial tissue (ST), often contain high endothelial venules and follicular dendritic cells (FDCs).	25963989
Inflammation	Altered Intercellular Communication	We established a strong link between NIK(+) ECs, (pre)FDCs, and the presence of TLSs, indicating that NIK(+) ECs may not only be important orchestrators of lymph node development but also contribute to the formation of TLSs in chronic inflammation.	25963989
Inflammation	Altered Intercellular Communication	In conclusion, our findings indicate that mtDNA variants can mediate methylation profiles and transcription for inflammation, angiogenesis and various signaling pathways, which are important in several common diseases.	25964427
Inflammation, Behavior Disorders	Altered Intercellular Communication	This may not only delay aging and prolong a youthful healthy life but also delay or prevent onset of several lifestyle-related diseases, of which oxidative stress and inflammation are the chief cause.	25964984
Inflammation	Altered Intercellular Communication	APN was an important factor for antagonizing inflammation and mitigating IR.	25966055
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Sulfatides have been shown to play a role in atherogenesis and vascular inflammation, resulting in atherosclerosis.	25966258
Inflammation, Inflammatory lesion	Altered Intercellular Communication	The Glasgow Prognostic Score (GPS) measures inflammation and proves its prognostic value in patients with extranodal natural killer (NK)/T-cell lymphoma (ENKTL) which is commonly combined with inflammatory lesion.	25966773
Tuberculoma, Inflammation, Primary malignant neoplasm, Inflammatory Myofibroblastic Tumor, Neoplasms, Tuberculosis	Altered Intercellular Communication	The corresponding pathological classification results (fungal inflammation, tuberculosis and tuberculoma, inflammatory pseudotumor, tumor middle differentiation, cancer) of quantized patients were treated as dependent variables.	25967875
Inflammation, Thrombosis, Hyperviscosity, Cerebral Infarction, Diabetic Ketoacidosis, Dehydration	Altered Intercellular Communication	Especially in patients who are genetically prone to thrombosis, cerebral infarction may develop due to inflammation, dehydration, and hyperviscocity secondary to DKA.	25968433
Glucose Intolerance (disease), Rhabdomyositis	Altered Intercellular Communication	MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling, and glucose intolerance.	25968578
Inflammation	Altered Intercellular Communication	Elevated inflammation and ceramide biosynthesis have been implicated in metabolic disruption and are linked to Toll-like receptor (TLR)/myeloid differentiation primary response 88 (MyD88) signaling.	25968578
Diabetes Mellitus	Altered Intercellular Communication	Interaction between Erythrocyte Phospholipid Fatty Acids Composition and Variants of Inflammation-Related Genes on Type 2 Diabetes.	25969153
Inflammation, Premature Obstetric Labor, Intestinal Obstruction	Altered Intercellular Communication	A 22-year -old woman, at 26 weeks of pregnancy, was admitted for premature labour, intestinal obstruction and systemic inflammation.	25969480
Cytomegalovirus Infections, Intraocular inflammation	Altered Intercellular Communication	The patient had a confirmed CMV infection as a cause of her intraocular inflammation via PCR DNA testing of an aqueous sample.	25969485
diabetic	Altered Intercellular Communication	One Egg per Day Improves Inflammation when Compared to an Oatmeal-Based Breakfast without Increasing Other Cardiometabolic Risk Factors in Diabetic Patients.	25970149
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	However, we have previously shown that eggs reduce inflammation in patients at risk for T2DM, including obese subjects and those with metabolic syndrome.	25970149
Inflammation	Altered Intercellular Communication	In contrast, eggs reduce AST and TNF-a in this population characterized by chronic low-grade inflammation.	25970149
Coronary Artery Disease	Altered Intercellular Communication	Recent studies suggest that the inflammation-associated protein calprotectin may be implicated in the pathogenesis of coronary artery disease (CAD).	25970343
Airway structure, Asthma, Obesity	Altered Intercellular Communication	Obesity is considered a risk factor for asthma, due to the induction of changes in airway mechanics and altered airway inflammation.	25970463
Granulomatous inflammation, Granulomatous	Altered Intercellular Communication	Specimens from patients with acute HZ were found to have small numbers of perineural plasma cells and most had subtle granulomatous inflammation, in patterns similar to the group with late granulomatous reactions.	25970643
Inflammation, Cardiovascular Diseases, Atherosclerosis	Altered Intercellular Communication	Cardiovascular disease is the leading cause of morbidity and mortality in hemodialysis patients; the increased risk of cardiovascular disease is due to accelerated atherosclerosis, inflammation and impaired lipoprotein metabolism.	25971848
Lesion, Fibrosis Assessment	Altered Intercellular Communication	Plasmin activity was observed almost exclusively in the TI space (mainly in the interstitium and partly in the tubular epithelial cells) and was significantly stronger in patients with TI lesion (tubular atrophy/interstitial fibrosis and tubulointerstitial inflammation) than in those without TI lesion.	25971850
Inflammation, Fibrosis Assessment, IGA Glomerulonephritis	Altered Intercellular Communication	These data suggest that TI plasmin is associated with TI inflammation leading to renal fibrosis, and can cause the decline in renal function seen in patients with IgAN.	25971850
Inflammation, Pain Distress Question, Autoimmune Diseases, Rheumatoid Arthritis, Spondylitis, Arthritis, Abnormal degeneration	Altered Intercellular Communication	Rheumatoid arthritis (AR), psoriatic arthritis (PSA) and ankylosing spondylitis (AS) are autoimmune systemic diseases characterized by inflammation, pain and joint degeneration.	25972066
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	The flavonoids epicatechin (in cocoa and tea) and quercetin (in tea) probably play a role by reducing endothelial dysfunction and inflammation, 2 main determinants of atherosclerosis.	25972527
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Plasma biomarkers of endothelial dysfunction and inflammation were measured at the start and end of each 4-wk intervention period.	25972527
Inflammation, Fibrosis Assessment, Diabetes Mellitus, Non-Insulin-Dependent, Kidney Diseases	Altered Intercellular Communication	A novel panel of biomarkers representing different pathways of renal disease progression including inflammation, fibrosis, angiogenesis, and endothelial function improved prediction of eGFR decline on top of established risk markers in type 2 diabetes.	25973922
Inflammation, Traumatic injury	Altered Intercellular Communication	Most injuries occur when anatomy is unclear due to the presence of anatomic variations, acute inflammation, or adhesions.	25974072
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Inflammation has received increasing attention as a cause of stroke.	25974422
Refractory anemias, Rheumatoid Arthritis, Inflammatory disorder	Altered Intercellular Communication	Both neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are reported to be increased in various inflammation-related diseases, but their clinical significance in rheumatoid arthritis (RA) remains unclear.	25974992
Inflammation, Carcinogenesis, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation contributes to human carcinogenesis and cancer progression.	25975177
Inflammation, Chronic sinusitis	Altered Intercellular Communication	Interleukin-25 and interleukin-33 as mediators of eosinophilic inflammation in chronic rhinosinusitis.	25975248
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	The initiating mediators of T-helper 2 inflammation, often seen in eosinophillic chronic rhinosinusitis (CRS), remains poorly understood.	25975248
Eosinophilic disorder, Inflammation	Altered Intercellular Communication	Interleukin (IL) 25, IL-33, and thymic stromal lymphopoietin (TSLP) are epithelial-derived cytokines implicated in the initiation of T-helper 2 inflammation and eosinophilia in other diseases.	25975248
Inflammation, Craniosynostosis	Altered Intercellular Communication	The expression of these cytokines was compared with phenotypic and histopathologic markers to investigate the factors that may drive eosinophilic inflammation in CRS.	25975248
Inflammation	Altered Intercellular Communication	Similar overexpression was seen in eosinophilic dominated inflammation (IL-25, p = 0.01; IL-33, p = 0.02) and patients with greater inflammatory severity.	25975248
Inflammation, Craniosynostosis	Altered Intercellular Communication	IL-25 and IL-33 overexpression was observed in eosinophilic CRS, The release of these cytokines by dysfunctional endothelium may perpetuate the eosinophillic inflammation in CRS.	25975248
Granulomatosis, Autoimmune Diseases, Airway structure, Vasculitis, CTCAE, Systemic Vasculitis	Altered Intercellular Communication	Granulomatosis with polyangiitis (GPA) is an autoimmune disease characterized by necrotizing granulomatous airway inflammation and vasculitis.	25975251
Sepsis, Inflammation	Altered Intercellular Communication	Soluble VE-cadherin is involved in endothelial barrier breakdown in systemic inflammation and sepsis.	25975259
Joint laxity, CLEFT LIP/PALATE WITH ABNORMAL THUMBS AND MICROCEPHALY, Unknown (origin) (qualifier value), Microspectrophotometry, Chronic musculoskeletal pain	Altered Intercellular Communication	Chronic Musculoskeletal Pain (MSP) in children can be due to non-inflammatory conditions, such as the benign joint hypermobility syndrome (BJHS) or idiopathic MSP (IMSP).	25976338
Inflammation, hepcidin, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	To explore the probable association of serum hepcidin and haemoglobin levels with iron and inflammation statuses in patients of chronic kidney disease stage 4 with anaemia.	25976565
ARCN1 gene, Inflammation	Altered Intercellular Communication	In summary, serum ITIH4 may be a PM10-specific biomarker in COPD and may be related to inflammation.	25977605
Inflammation	Altered Intercellular Communication	In addition, chronic inflammation produced by Gaucher cells induces the production of several cytokines, which leads to direct changes in the bone remodelling process and can also affect the process indirectly through other immune cells.	25978039
Inflammation, Electrocardiogram: myocardial infarction (finding), Anemia	Altered Intercellular Communication	Anemia and Inflammation in ST-Segment Elevation Myocardial Infarction.	25978119
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Immune semaphorins are a large family of proteins involved in the pathogenesis of inflammatory diseases through the regulation of immune homeostasis and tissue inflammation.	25978359
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	We aim to assess the possible involvement of semaphorin3A (sema3A) and 4A (sema4A) in peripheral immune responses and bowel tissue inflammation of patients suffering from Crohn's disease (CD) and ulcerative colitis (UC).	25978359
Inflammatory Bowel Diseases, Inflammation, Failure (biologic function)	Altered Intercellular Communication	Altered % of Tregs expressing sema3A in patients with inflammatory bowel diseases (IBD) is partially responsible for their failure in preventing CD4+ effector T cell induced inflammation in IBD in peripheral blood.	25978359
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The increased expression of sema4A in bowel biopsies from CD and UC patients is suggestive of its central role in regulating local tissue inflammation in the bowel.	25978359
Inflammation, Hypoxia	Altered Intercellular Communication	Proteins related to hypoxia, angiogenesis, and inflammation were significantly elevated in the vitreous of CRVO patients.	25978399
Inflammation, Swelling	Altered Intercellular Communication	There was no history of inflammation or swelling of the eyelid.	25978533
Inflammation, Eales disease, PDR gene, Diabetic Retinopathy, Polypoidal choroidal vasculopathy, Retinal Diseases, Retinal Vein Occlusion	Altered Intercellular Communication	To examine the expression of pro-interleukin-1b (pro-IL-1b) and interleukin-1b (IL-1b) in the vitreous body of patients with neovascular age-related macular degeneration(nAMD), polypoidal choroidal vasculopathy (PCV), proliferative diabetic retinopathy (PDR), retinal vein occlusion (RVO) or Eales' disease to further elucidate the role of IL-1b and inflammation in the pathogenesis of neovascular retinal disease.	25978536
Crohn Disease, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	New cases of ulcerative colitis (UC) and Crohn's disease (CD) were retrieved by thorough review of all small and large intestinal pathology reports with any type of inflammation from all the pathology departments in Iceland for the period 1995-2009.	25979112
Eosinophilic disorder, Eosinophilic Granuloma, Inflammation, Systemic Vasculitis	Altered Intercellular Communication	Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare eosinophil-rich disorder characterised by necrotising granulomatous inflammation affecting small to medium sized vessels.	25979957
Cessation of life, Inflammation, Malnutrition	Altered Intercellular Communication	In Cox analyses, T3 level was a significant predictor of all-cause mortality (per 10-unit increase, adjusted hazard ratio [HR], 0.86; 95% confidence interval [95% CI], 0.78 to 0.94; P=0.002), CV death (per 10-unit increase, adjusted HR, 0.84; 95% CI, 0.75 to 0.98; P=0.01), and sudden death (per 10-unit increase, adjusted HR, 0.69; 95% CI, 0.56 to 0.86; P=0.001) after adjusting for well known risk factors including inflammation and malnutrition.	25979970
Inflammation, Esophageal diverticulum	Altered Intercellular Communication	Other reasons, such as compression of the tracheal intubation balloon and repeated inflammation of the oesophageal diverticulum, may also have contributed to the recanalisation.	25980770
Inflammation, Rheumatism	Altered Intercellular Communication	In the case of rheumatic diseases, the synovial joint cavity represents a secluded area of inflammation which could harbor etiological agents.	25980837
Communicable Diseases, Inflammation	Altered Intercellular Communication	IL-1a plays an important role in inflammation, immunity and defense against infection.	25981582
Inflammation, Pulmonary Edema, Alveolar Epithelial Cells, Hemorrhage	Altered Intercellular Communication	DAD is characterized by hyaline membrane formation, lung edema, inflammation, hemorrhage and alveolar epithelial cell injury.	25981598
Pain Distress Question, Knee pain, Depression, CTCAE, Bipolar Disorder	Altered Intercellular Communication	Among the potential contributors, we hypothesized that coexisting depressive symptoms might increase the severity of knee pain because the increased cytokine levels and neurotransmitter changes related to depression are known to influence the threshold of physical pain perception.	25982621
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Acute myocardial infarction activates distinct inflammation and proliferation pathways in circulating monocytes, prior to recruitment, and identified through conserved transcriptional responses in mice and humans.	25982896
Inflammation	Altered Intercellular Communication	Patterns of gene expression associated with inflammation and proliferation appear to be switched on prior to their infiltration of injured myocardium suggesting that the specific targeting of inflammatory and proliferative processes in these immune cells in humans are possible therapeutic strategies.	25982896
Inflammation, Gastritis, Myocarditis, CTCAE 5.0, Nephritis	Altered Intercellular Communication	However, the GSH level in erythrocytes from people who had inflammation (myocarditis, nephritis and gastritis) was generally higher than that from the healthy people.	25983061
Inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Serum Cyr61 is associated with clinical disease activity and inflammation in patients with systemic lupus erythematosus.	25984669
Inflammation, Lupus Erythematosus, Systemic	Altered Intercellular Communication	In conclusion, serum Cyr61 was increased in patients with SLE which was associated with clinical disease activity and inflammation in SLE, suggesting Cyr61 may be a novel potential auxiliary marker for the diagnosis of SLE.	25984669
Inflammatory Bowel Diseases, Gingivitis, Dental Plaque	Altered Intercellular Communication	Children with IBD compared with controls had a statistically significant (P < 0.001) higher dmf-t (2.95 versus 0.91) or DMF-T (5.81 versus 2.04) index and a higher gingival inflammation (simplified gingival, 40% versus 24%) although the respectively dental plaque index showed no significant difference (plaque control record, 42% versus 41%).	25985243
Airway structure, Bronchial Hyperreactivity	Altered Intercellular Communication	However, an ACT does not include assessment of airway inflammation, which is better reflected when measuring nonspecific bronchial hyperresponsiveness (BHR).	25985789
Glomerulonephritis, Interstitial inflammation	Altered Intercellular Communication	He had a renal biopsy, which revealed acute immune complex glomerulonephritis with interstitial inflammation.	25986232
Inflammation	Altered Intercellular Communication	Overall, concordance between endoscopic and histological remission was moderate (k=0.56, 95% CI 0.36 to 0.77); 24% patients had persistent inflammation despite endoscopic remission.	25986946
Primary malignant neoplasm	Altered Intercellular Communication	Systemic inflammatory response was shown to play an important role in development and progression of many cancer types and different inflammation-based indices were used for determining prognosis.	25987075
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The higher levels of p21 in OA MPCs are also correlated with a decreased chondrogenic differentiation capacity and synovial inflammation, however, there was no evidence of senescence in the OA cells.	25987237
Hepatitis B Virus-Related Hepatocellular Carcinoma, Inflammation	Altered Intercellular Communication	Inflammation scores predict survival for hepatitis B virus-related hepatocellular carcinoma patients after transarterial chemoembolization.	25987783
Hepatitis B Virus-Related Hepatocellular Carcinoma, Inflammation, FAM126A gene	Altered Intercellular Communication	To compare the prognostic ability of inflammation scores for patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) undergoing transarterial chemoembolization (TACE).	25987783
Inflammation, FAM126A gene	Altered Intercellular Communication	The prognostic ability of GPS is superior to other inflammation scores for HCC patients undergoing TACE.	25987783
Refractory anemias, Arthralgia, Inflammation	Altered Intercellular Communication	CVD incidence was increased in women with RA versus women with no reported RA at almost all risk factor levels, except for low levels of joint pain or inflammation.	25988241
Refractory anemias, Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Among women with RA, inflammation was more strongly associated with fatal CVD and total mortality than with CHD or CVD.	25988241
Arthralgia, Inflammation	Altered Intercellular Communication	CVD risk was strongly associated with CVD risk factors, joint pain severity, and inflammation, but not with anti-CCP positivity or RF positivity.	25988241
Arterial Stiffness, Inflammation, Rheumatoid Arthritis, Carotid Intima-Media Thickness	Altered Intercellular Communication	There was no correlation between arterial stiffness index and common carotid intima-media thickness with markers of inflammation and disease activity in hypertensive rheumatoid arthritis patients.	25990366
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Reduced bacterial colony count of anaerobic bacteria is associated with a worsening in lung clearance index and inflammation in cystic fibrosis.	25992575
Orthodontic, Inflammation, Dental Plaque	Altered Intercellular Communication	Alterations in plaque accumulation and gingival inflammation promoted by treatment with self-ligating and conventional orthodontic brackets.	25992985
Chronic inflammation	Altered Intercellular Communication	However, here we hypothesized that a tonsillolith can also be formed by chronic saliva stasis in the tonsillar tissue, without any signs of chronic inflammation.	25993312
Inflammation, Obesity	Altered Intercellular Communication	Activation of adipose tissue inflammation is associated with obesity caused by lipid accumulation in adipocytes.	25993353
Inflammation, Carcinogenesis	Altered Intercellular Communication	In addition to its role as a transport protein, the vitamin D binding protein (DBP) may also affect lipid metabolism, inflammation and carcinogenesis.	25993554
ARCN1 gene, Inflammation	Altered Intercellular Communication	COPD is a progressive disease of the airways that is characterized by neutrophilic inflammation, a condition known to promote the excessive formation of neutrophil extracellular traps (NETs).	25994149
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Type-2 diabetes is associated with systemic inflammation and higher C-reactive protein (CRP) levels.	25994228
Inflammation, Diabetes Mellitus, Cardiovascular Diseases	Altered Intercellular Communication	Understanding such associations may shed light on the role of inflammation in development of type-2 diabetes and its complications such as cardiovascular diseases.	25994228
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	In this study we found longitudinal observational evidence suggesting that increase in systemic inflammation is associated with an increase in HbA1c and thus systemic inflammation may have a role in development of type-2 diabetes and its complications.	25994228
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Monocyte-to-HDL ratio (M/H ratio) is a recently emerged indicator of inflammation and oxidative stress which have been only studied in patients with chronic kidney disease.	25995388
Inflammation	Altered Intercellular Communication	A 58-year-old woman presented painful chronic inflammation of the outside skin of the bilateral soles.	25997079
Inflammation, Stanford Cancer Institute	Altered Intercellular Communication	](Ct)) method in subclinical inflammation (SCI, n=10), clinical inflammation in acute T-cell mediated rejection (CI, n=10) and no rejection samples (n=9).	25997515
Inflammation, PTAFR gene	Altered Intercellular Communication	Clinical inflammation group showed a increased expression of genes for chemotaxis mediating cytokines (CCL1, CCL17, CCL24, CCL25, CCL26), cytokine receptors (CCR1, CCRL2, IL1RAPL2, CXCR5), proinflammatory cytokines (IL12A, LTA), inflammatory mediator (PTAFR), complement protein C3, executioner protein of apoptosis (CASP7), growth factor (TGFA), colony stimulating factor (CSF-2), proteins involved in dendritic cells differentiation and interaction (CD209, LAMP3), regulation of immune response (LILRB2, LILBRB4).	25997515
Nephritis	Altered Intercellular Communication	Subclinical acute kidney inflammation has transcriptional profile of immune injury of lower extend compared to clinical acute inflammation.	25997515
Symptoms, Inflammation	Altered Intercellular Communication	Child maltreatment, inflammation, and internalizing symptoms: Investigating the roles of C-reactive protein, gene variation, and neuroendocrine regulation.	25997771
Symptoms, Inflammation	Altered Intercellular Communication	Our findings highlight the importance of the timing of child maltreatment and have important implications for characterizing variability in inflammation and internalizing symptoms among youth.	25997771
ARCN1 gene, Chronic inflammation, airway disease, Chronic Obstructive Airway Disease, Asthma	Altered Intercellular Communication	Obstructive airway diseases, such as asthma and chronic obstructive pulmonary disease (COPD), have airflow limitation associated with chronic inflammation.	25998444
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Abnormal levels of microRNA (miR)-155, which regulate inflammation and immune responses, have been demonstrated in the colonic mucosa of patients with inflammatory bowel diseases (IBD), although its role in disease pathophysiology is unknown.	25998827
Renal Insufficiency, Inflammation, Anemia, hepcidin	Altered Intercellular Communication	In the absence of overt renal impairment, anemia in T2DM is associated with chronic inflammation, inducing elevation of hepcidin and GDF15 levels independently of the erythropoietin level.	25998917
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Cigarette smoking is a major risk factor in the progression of atherosclerosis and has been shown to cause endothelial dysfunction, inflammation, and modification of lipid profile.	25999135
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Improved insulin sensitivity and reduced inflammation are among the hypothesized mechanisms by which coffee drinking may affect cancer risk; however, associations between coffee drinking and systemic levels of immune and inflammatory markers have not been well characterized.	25999212
Inflammation, diabetic	Altered Intercellular Communication	Is vitamin D deficiency related to accumulation of advanced glycation end products, markers of inflammation, and oxidative stress in diabetic subjects?	26000307
Inflammation, Primary malignant neoplasm, Atherosclerosis	Altered Intercellular Communication	Our current understanding of the patholobiology of these fundamental disorders suggests that inflammatory processes may differentially affect them; thus, atherosclerosis can be largely driven by inflammation, where as cancer often flourishes as inflammatory responses are modulated.	26000958
Neoplasms	Altered Intercellular Communication	Furthermore, this correlation is not uniformly associated with anti-neoplastic treatment, suggesting that the inverse relationship may be in part attributable to an individual's intrinsic inflammatory propensity, and/or to inflammation-modulatory properties of neoplasms.	26000958
Refractory anemias, Inflammation	Altered Intercellular Communication	These results suggest that thrombin can exacerbate inflammation in RA by impairing the MPO inhibitory function of CP via proteolysis and by competitively inhibiting CP ferroxidase activity.	26001728
Inflammation, Necrosis of retina, Retinal Vasculitis, Vitreous body structure	Altered Intercellular Communication	Progressive outer retinal necrosis is characterized clinically as showing minimal or no inflammation in the aqueous and vitreous humors, absence of retinal vasculitis, and patches of yellowish spots located deep in the retina.	26002429
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	The protein related with this gene is accumulated within the endoplasmic reticulum of hepatocytes causing their damage, inflammation and cirrhosis.	26003074
Infection, Helicobacter Infections	Altered Intercellular Communication	Rare Helicobacter pylori organisms accounted for 58.0% of all atypical infections; the next most common atypical Helicobacter infection was that with minimal or no gastric inflammation (23.3% of atypical infections).	26003395
Inflammation, Pain Distress Question, Necrosis, Edema, Hypertrophy	Altered Intercellular Communication	Histologically, hypertrophy and inflammation of the tendon and hypertrophy, inflammation, oedema and necrosis of the subacromial bursa were directly associated with pain (P < 0.05).	26003482
Asthma, IL13 gene	Altered Intercellular Communication	Accumulating evidence is indicating that hormonal factors play a role in new-onset allergic rhinitis and asthma after puberty.	26003905
Osteolysis	Altered Intercellular Communication	The pharmacological targeting of ER-stress-mediated inflammatory signaling pathways might be an appealing approach for alleviating or preventing particle-induced osteolysis in at-risk patients.	26004143
Airway structure, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Patients with chronic obstructive pulmonary disease and chronically colonized with Haemophilus influenzae during stable disease phase have increased airway inflammation.	26005341
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure, Colonization	Altered Intercellular Communication	Some patients with chronic obstructive pulmonary disease (COPD) show increased airway inflammation and bacterial colonization during stable phase.	26005341
Airway structure	Altered Intercellular Communication	The difference in airway inflammation seen during stable phase in patients chronically colonized with H. influenzae was not observed during exacerbations.	26005341
ARCN1 gene, Airway structure	Altered Intercellular Communication	Some COPD patients who were chronically colonized with H. influenzae during stable phase showed increased airway inflammation and reduced lung volumes when compared with non-chronically colonized patients.	26005341
Myocarditis	Altered Intercellular Communication	Imaging of myocardial inflammation with somatostatin receptor based PET/CT - A comparison to cardiac MRI.	26005805
Myocarditis, CTCAE 5.0, Myocarditis	Altered Intercellular Communication	Acute myocarditis as well as post-ischemic myocardial inflammation are generally associated with a profound activation of the immune system.	26005805
Sepsis, Inflammation	Altered Intercellular Communication	Matrix metalloproteinases (MMPs)-8 and -9 are released from neutrophils and activated in sepsis to participate in inflammation in several ways.	26008138
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Cluster of differentiation 93 (CD93) is involved in apoptosis and inflammation and has a suggested role in angiogenesis, and all of which are involved in the development and dissemination of cancer.	26008729
One Vessel Coronary Disease, Inflammation, Atherosclerosis	Altered Intercellular Communication	Background Various pathophysiological mechanisms such as microvascular and endothelial dysfunction, small vessel disease, diffuse atherosclerosis, and inflammation have been held responsible in the etiology of coronary slow flow.	26008865
Acute and chronic inflammation	Altered Intercellular Communication	On recent admission, blood tests, endoscopies and CT scans indicated chronic colonic inflammation.	26009604
Inflammation	Altered Intercellular Communication	Treatment strategies for bowel inflammation were unsuccessful and the patient was subsequently discussed at a multidisciplinary team meeting with surgeons for consideration of colectomy.	26009604
Inflammation, Diarrhea, Peptic Ulcer	Altered Intercellular Communication	It is important that clinicians are aware of the link between pharmacotherapy, specifically nicorandil and gastrointestinal ulceration and inflammation causing severe diarrhoea.	26009604
Respiratory Distress Syndrome, Adult, Inflammation	Altered Intercellular Communication	The results suggest that the peak in plasma MMP-9 activity may precede the peak of neutrophil inflammation in the airways and lung tissue in the setting of ARDS.	26009816
Traumatic injury	Altered Intercellular Communication	Impact of Injury Severity on Dynamic Inflammation Networks Following Blunt Trauma.	26009819
Inflammation, Nonpenetrating Wounds	Altered Intercellular Communication	We hypothesized that dynamic networks of systemic inflammation manifest differently as a function of injury severity in human blunt trauma.	26009819
Inflammation, Superficial ulcer	Altered Intercellular Communication	Based on clinical observation, inflammatory markers, and radiographic reports, in the follow-up visits, they remain with no signs of inflammation and no new erosions on radiograph.	26010182
Inflammation, Asthma	Altered Intercellular Communication	Secondary outcome measures were symptoms, episodes of poor asthma control, Asthma Control Test score (range, 5-25; higher scores indicate better control), and systemic and airway biomarkers of inflammation.	26010632
Delirium, Inflammation, Critical Illness	Altered Intercellular Communication	We investigated whether exposure to medication with anticholinergic properties increases the probability of transitioning to delirium in critically ill adults and whether this relationship is affected by age or the presence of acute systemic inflammation.	26010688
Inflammation, Cardiac complication, Hemodynamic instability	Altered Intercellular Communication	Patients with SCM and systemic inflammation with hemodynamic instability might be susceptible to TAWT, which is often associated with cardiac complications.	26011273
Hyperlipidemia	Altered Intercellular Communication	Evidence in obese children: contribution of hyperlipidemia, obesity-inflammation, and insulin sensitivity.	26011530
Inflammation, Dyslipidemias, Obesity	Altered Intercellular Communication	Evidence shows a high incidence of insulin resistance, inflammation and dyslipidemia in adult obesity.	26011530
Inflammation, Overweight	Altered Intercellular Communication	The overweight subjects only exhibited significant insulin resistance and low-grade inflammation.	26011530
palladium, Inflammation, Acute peritonitis, Peritonitis	Altered Intercellular Communication	We enrolled 53 PD patients: 30 without any history of systemic inflammation or peritonitis in the last 3 months (group A) and 23 with acute peritonitis (group B).	26012380
Inflammation, Osteopenia, Peri-Implantitis	Altered Intercellular Communication	Eighteen individuals diagnosed with peri-implantitis (clinical signs of inflammation and progressive bone loss) on at least two implants were included.	26013241
Inflammation, Bipolar Disorder	Altered Intercellular Communication	The association between depressive traits and CVD may be moderated by low-grade inflammation.	26013320
Inflammation, Fibrosis Assessment, Thrombosis	Altered Intercellular Communication	However, the inflammation also leads to progressive fibrosis and occlusion of the veins without thrombosis.	26013364
Inflammation, Calcinosis	Altered Intercellular Communication	Significant correlations were found between prostatic calcification and the severity of inflammation (P<0.02) as well as the NIH-CPSI subdomain of urinary symptoms (P<0.02).	26013949
Inflammation, Obesity	Altered Intercellular Communication	The inverse association of carotenoids with obesity measures may reflect reduced micronutrient concentrations owing to inflammation associated with obesity.	26014267
Sunburn, Skin Carcinogenesis, Inflammation	Altered Intercellular Communication	Increasing evidence has identified ultraviolet radiation (UVR) as the skins most potent mutagen as over exposure results in sunburn, inflammation and DNA damage, thus contributing to a photo-ageing phenotype and possibly skin carcinogenesis.	26014614
Inflammation, Obesity	Altered Intercellular Communication	Obesity was associated with systemic inflammation, greater leg fat mass, and patterns of mRNA expression consistent with muscle deconditioning, whereas leg lean mass, strength, and work done during maximal exercise were no different.	26015550
Tendinitis	Altered Intercellular Communication	This tendinitis may also occur in patients with systemic inflammatory conditions and is classified as posterior tibial tendon dysfunction stage I.	26016290
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Stroke patients had lower HDL-cholesterol than controls and a remarkable fall in PON1 activity (control group-227U/L, survivors-42U/L, lethal outcome group-61U/L, p < 0.001), along with more prominent inflammation.	26016451
Inflammation, Arteritis	Altered Intercellular Communication	Regulation of Inflammation and Angiogenesis in Giant Cell Arteritis by Acute-Phase Serum Amyloid A.	26016600
Inflammation, vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Acute-phase serum amyloid A (A-SAA) is an acute-phase reactant, but is also produced at sites of inflammation and may contribute to vascular inflammation in atherosclerosis.	26016600
Arteritis	Altered Intercellular Communication	Our findings demonstrate a functional role for A-SAA in regulating temporal artery inflammation, angiogenesis, and invasion, all key processes in the pathogenesis of GCA.	26016600
ARCN1 gene, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Preliminary studies have shown that both airflow obstruction and systemic inflammation may contribute to endothelial dysfunction in COPD.	26016823
Inflammation, Kidney Diseases	Altered Intercellular Communication	Serum retinol--a VAD marker--increases in kidney disease and decreases in inflammation, which can partly be attributed to alterations in the vitamin A-transport proteins retinol-binding protein 4 (RBP4) and prealbumin.	26016862
Abnormal renal function, Inflammation, Hypertension, CTCAE, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Kidney dysfunction and inflammation commonly accompany T2D and hypertension.	26016862
Inflammation, Hypertension, CTCAE, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Among urban Ghanaians, we investigated the associations of T2D and hypertension with serum retinol as well as the importance of kidney function and inflammation in this regard.	26016862
Intraocular inflammation, Abscess	Altered Intercellular Communication	He received an empirical antibiotic and antiviral agent intravenously followed by oral prednisolone until the etiology was identified; however, intraocular inflammation in the left eye continued to worsen, followed by the development of subretinal abscess in the contralateral eye.	26017191
Inflammation, Respiratory Tract Infections, Equilibration disorder	Altered Intercellular Communication	The onset of the balance disorder was preceded by respiratory infection: common cold with symptoms of inflammation of the mucous membrane in the nose and throat.	26017723
Inflammation, hafnium	Altered Intercellular Communication	We hypothesized that mitochondrial respiratory dysfunctions of peripheral blood mononuclear cells (PBMCs) may be associated with inflammation and oxidative stress in early-stage HF patients complicated with cardiometabolic risk factors.	26018291
Inflammation, Congenital Heart Defects, hafnium	Altered Intercellular Communication	It showed that excessive inflammation and reduced antioxidant capacity were closely associated with cardiac abnormalities in early-stage HF patients.	26018291
Inflammation, Disturbance	Altered Intercellular Communication	Our study indicated that cardiometabolic risk factor-mediated mitochondrial respiratory dysfunctions of PBMCs link with the cellular inflammation / oxidative stress and cardiac disturbance in early-stage HF.	26018291
Inflammation, Prostate carcinoma	Altered Intercellular Communication	A guided biopsy by ultrasonography was performed revealing a prostate carcinoma and inflammation in both prostatic lobes.	26018697
Renal Insufficiency, Inflammation	Altered Intercellular Communication	Our results demonstrate a stage-dependent plasma Ab increase that is augmented by loss of glomerulotubular integrity, low body weight, and inflammation, demonstrating a multifaceted role of renal dysfunction in Ab retention.	26019016
Allergic, Acute and chronic inflammation	Altered Intercellular Communication	The integrity of the epithelial layer in the gastrointestinal tract protects organisms from exposure to luminal antigens, which are considered the primary cause of chronic intestinal inflammation and allergic responses.	26019243
Inflammation, Colitis	Altered Intercellular Communication	Our findings support the hypothesis that a luminal factor triggers the inflammation observed in collagenous colitis.	26019474
Lymphadenopathy	Altered Intercellular Communication	The Kimura disease is a benign rare inflammatory condition of the soft tissue, especially of the head and neck region presenting as painless nodule with or without lymphadenopathy.	26020715
Inflammation, Gastrointestinal mucositis, Peri-Implantitis	Altered Intercellular Communication	A controlled, cross-sectional exploratory study on markers for the plasminogen system and inflammation in crevicular fluid samples from healthy, mucositis and peri-implantitis sites.	26021226
Inflammation, Gastrointestinal mucositis, Peri-Implantitis	Altered Intercellular Communication	Markers for the plasminogen system and inflammation could be used to distinguish between mucositis and peri-implantitis.	26021226
Inflammation, Gastrointestinal mucositis, Peri-Implantitis	Altered Intercellular Communication	The results suggested that the plasminogen system was sufficiently upregulated allowing for resolution of inflammation and healing at the inflamed implant site in subjects with mucositis, whereas such upregulation was insufficient resulting in impaired healing and prolonged inflammation in subjects with peri-implantitis.	26021226
Inflammation, Osteopenia	Altered Intercellular Communication	The combination of tissue inflammation and low levels of tPA was a strong predictor of marginal bone loss in this study.	26021226
Inflammation	Altered Intercellular Communication	This case demonstrates that masses in the craniocervical junction can be varied in pathology and when there is evidence of systemic inflammation, HP should be considered.	26021381
Fibrosis Assessment, Thickened	Altered Intercellular Communication	Histology showed densely collagenous tissue with scanty psammoma bodies and multinucleate giant cells, consistent with hypertrophic pachymeningitis (HP)-a rare, chronic inflammatory condition, characterised by thickening and fibrosis of the dura.	26021381
Granulomatosis, Inflammation, Vasculitis, CTCAE, Systemic Vasculitis	Altered Intercellular Communication	Granulomatosis with polyangiitis (GPA) is a systemic necrotizing vasculitis, associated with antineutrophil cytoplasmic autoantibody-associated systemic vasculitis, and it can affect many organ systems via the inflammation of small-to-medium-sized vessels.	26021454
Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Current evidence links atrial fibrillation (AF) to the inflammation.	26021499
Inflammation	Altered Intercellular Communication	However, the role of inflammation in the atrial electrophysiological remodeling indexed by P-wave dispersion (P d ) remains unclear.	26021499
Inflammation	Altered Intercellular Communication	The interaction between hs-CRP and AF may be mediated by P d , suggesting an important role of inflammation in the atrial electrophysiological remodeling predisposing to AF.	26021499
Orchitis, Malignant Neoplasms	Altered Intercellular Communication	Currently, 64-slice multidetector CT scanners are capable of providing higher-resolution images and may be able to distinguish malignancy from diverticular inflammation.	26022155
Inflammation, COL4A2 wt Allele, Cerebral Hemorrhage	Altered Intercellular Communication	Inflammation may provoke cerebral arteriolar ectasia, inducing microaneurysm formation and further promoting intracerebral hemorrhage (ICH).	26024006
Sepsis, Inflammation	Altered Intercellular Communication	Peptide 19-2.5 inhibits heparan sulfate-triggered inflammation in murine cardiomyocytes stimulated with human sepsis serum.	26024383
Sepsis, Inflammation, Myocardial dysfunction	Altered Intercellular Communication	Myocardial dysfunction in sepsis has been linked to inflammation caused by pathogen-associated molecular patterns (PAMPs) as well as by host danger-associated molecular patterns (DAMPs).	26024383
Myocarditis	Altered Intercellular Communication	Based on these findings, peptide 19-2.5 is a novel anti-inflammatory agent interacting with both PAMPs and DAMPs, suggesting peptide 19-2.5 may have the potential for further development as a broad-spectrum anti-inflammatory agent in sepsis-induced myocardial inflammation and dysfunction.	26024383
Inflammation, Fibrosis Assessment, Hepatitis B	Altered Intercellular Communication	Chronic Hepatitis B Virus Infection: The Relation between Hepatitis B Antigen Expression, Telomere Length, Senescence, Inflammation and Fibrosis.	26024529
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We also investigated the relation between inflammation, fibrosis and cell cycle phase.	26024529
Granulomatosis, Inflammation, Systemic Vasculitis, Atherosclerosis	Altered Intercellular Communication	The interface of inflammation and subclinical atherosclerosis in granulomatosis with polyangiitis (Wegener's): a preliminary study.	26024800
Inflammation, Atherosclerosis	Altered Intercellular Communication	The cumulative burden of systemic inflammation in GPA correlated with the development of subclinical atherosclerosis.	26024800
Inflammation, Mucopolysaccharidosis I, Atherosclerosis	Altered Intercellular Communication	The findings of increased levels of circulating leukocyte-derived MPs and enhanced platelet reactivity during relapse suggest possible roles for MPs and platelets in disease pathogenesis and support a growing literature that links inflammation, atherosclerosis, and platelet activation.	26024800
Inflammation	Altered Intercellular Communication	No significant difference regarding anterior chamber inflammation and discomfort was observed between the 3 groups.	26025033
Intraocular inflammation	Altered Intercellular Communication	There was no difference in intraocular pressure reduction, intraocular inflammation or ocular discomfort post-SLT when comparing the 3 treatment modalities.	26025033
Sepsis, Inflammation	Altered Intercellular Communication	Sepsis is a lethal outcome of the inflammation and coagulation process.	26025100
Sepsis, Tumor necrosis, Inflammation	Altered Intercellular Communication	Human interleukin (IL)-6 and tumor necrosis factor (TNF) a are well-known inflammation factors closely associated with sepsis.	26025100
Inflammation, Ototoxicity	Altered Intercellular Communication	During inflammation, the kynurenine pathway (KP) metabolises the essential amino acid tryptophan (TRP) potentially contributing to excitotoxicity via the release of quinolinic acid (QUIN) and 3-hydroxykynurenine (3HK).	26025142
Inflammation, Fibrosis Assessment, Bronchioles, Pneumonia, Interstitial	Altered Intercellular Communication	Almost 60% of UIP/IPF explants showed NSIP areas and 41% peribronchiolar fibrosis; inflammation, bronchiolar metaplasia, and vascular changes were more frequent in UIP/IPF explants; and Desquamative Interstitial Pneumonia (DIP)-like areas were not common (18%-27%).	26025258
Cholecystitis	Altered Intercellular Communication	This was verified in an in vivo model using a pathogenic E. coli isolated from one of the patients in guinea pigs and observed marked gallbladder inflammation and morphologic changes.	26025761
Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain scores were higher at the laparoscopic port incision sites than in upper abdominal sites distant from incisions or expected inflammation, mean (SD) 3.3 (2.3) and 1.1 (1.8), respectively (p < .0001).	26025797
Inflammation	Altered Intercellular Communication	Pouch Inflammation Is Associated With a Decrease in Specific Bacterial Taxa.	26026389
Inflammation, Crohn Disease	Altered Intercellular Communication	Because the inflammation occurs in a previously normal small bowel, studies of this process might provide information about the development of Crohn's disease.	26026389
Inflammation	Altered Intercellular Communication	Patients were assigned to groups based on their degree and type of pouch inflammation.	26026389
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Reductions in protective bacteria and increases in inflammatory bacteria are associated with pouch inflammation in patients with UC who underwent pouch surgery.	26026389
Inflammation, Carcinogenesis, Colorectal Carcinoma	Altered Intercellular Communication	Patients with colorectal cancer (CRC) have high circulating levels of macrophage inhibitory cytokine-1 (MIC1 or growth differentiation factor 15), a marker of inflammation that might be involved in carcinogenesis.	26026393
malignant disease, Inflammation	Altered Intercellular Communication	Mast cells play an important role in inflammation and angiogenesis in malignant diseases.	26026586
Inflammation, Chronic disease	Altered Intercellular Communication	Inflammation increases the risk of chronic diseases, but the links between emotional responses to daily events and inflammation are unknown.	26030309
Inflammation	Altered Intercellular Communication	Women who experience increased negative affect when faced with minor stressors may be at particular risk of elevated inflammation.	26030309
Adrenocorticotropic hormone (ACTH) deficiency (disorder)	Altered Intercellular Communication	Hormonal investigations showed partial corticotropic and thyrotropic deficiencies.	26030326
Inflammation	Altered Intercellular Communication	Activin A, a member of the TGF-b superfamily, plays an important role in inflammation and remodeling in the lower airways, although its expression and release in the upper airways remain undescribed.	26030615
Inflammation, Malnutrition, Restless Legs Syndrome	Altered Intercellular Communication	Relationships Between Malnutrition, Inflammation, Sleep Quality, and Restless Legs Syndrome in Hemodialysis Patients.	26031339
Kidney Diseases	Altered Intercellular Communication	Temporal serum creatinine increase and exacerbation of tubulointerstitial inflammation during the first two months in resolving polyomavirus BK nephropathy.	26031586
Inflammation, Primary Graft Dysfunction	Altered Intercellular Communication	Temporal graft dysfunction and increased inflammation, called immune reconstitution, were observed at 2 months.	26031586
Vasculitis, Endarteritis, Glomerulitis (disorder), Peritubular Capillaritis Assessment	Altered Intercellular Communication	Microvascular inflammation, such as glomerulitis, peritubular capillaritis, and arteriole endarteritis were also detected.	26031589
Inflammation	Altered Intercellular Communication	A 1-hour protocol biopsy revealed C4d-positivity and mild peritubular capillary inflammation.	26031595
Glomerulitis (disorder), GPR182 gene, Inflammation	Altered Intercellular Communication	A second graft biopsy was performed, which showed overt AMR with glomerulitis, peritubular capillary inflammation and no C4d deposition.	26031595
Inflammation, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	Angiogenesis and chronic inflammation are known to be co-dependent in atherosclerosis and cardiovascular diseases.	26032258
Inflammation, Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	Inflammation plays a crucial role in tumor growth, metastasis, and survival.	26032829
Communicable Diseases, Inflammation, Intoxication	Altered Intercellular Communication	In patients who exhibit signs of inflammation or infection with increased C-reactive protein values during psychopharmacological treatment, especially under clozapine and risperidone, therapeutic drug monitoring is recommendable in order to minimize the risk of intoxications due to elevated drug concentrations.	26032842
Respiratory Distress Syndrome, Adult, Inflammation, Endothelium	Altered Intercellular Communication	In the multicenter study, patients with direct ARDS also had lower levels of von Willebrand factor antigen and IL-6 and IL-8, markers of endothelial injury and inflammation, respectively.	26033126
Nonalcoholic Steatohepatitis, Inflammation, Cholangitis	Altered Intercellular Communication	Two cases did not fit into the above 2 histologic groups: 1 showed portal inflammation with cholangitis, and the other showed morphologic features indistinguishable from nonalcoholic steatohepatitis.	26034866
Inflammation, Fracture	Altered Intercellular Communication	Polymorphisms in inflammation associated genes ALOX15 and IL-6 are associated with bone properties in young women and fracture in elderly.	26036173
Inflammation, Fracture	Altered Intercellular Communication	This study suggests that variation in inflammation related genes ALOX15 and IL6 was associated with bone microarchitecture and density in young adult women, but appears to be less important in the elderly, despite an observed association with CRP as a marker of inflammation and incident fracture.	26036173
Inflammation, Fibromyalgia, Endothelial dysfunction	Altered Intercellular Communication	Recent evidence suggests that fibromyalgia syndrome (FS) is associated with inflammation and endothelial dysfunction.	26036530
Sandawe language, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Considering the significant association of visceral fat with inflammation and cardiovascular disease, estimating visceral fat by means of SAD could be a useful tool to stratify cardiovascular risk as well as graft function in renal transplant recipients.	26036544
Pancreatic Trypsin Secretory Inhibitor, Kazal, Carcinogenesis, Inflammation	Altered Intercellular Communication	Serine protease inhibitor Kazal type-1 (SPINK1), a trypsin kinase inhibitor, is involved in inflammation, cell proliferation and carcinogenesis.	26037168
Inflammation, Arterial calcification, Chronic Kidney Diseases	Altered Intercellular Communication	The objective of the study was to determine the relationship between common carotid artery intima-media thickness (CCA-IMT) and histologically assessed calcification of radial artery in relation to clinical features and laboratory markers of bone and mineral metabolism, inflammation, and oxidative stress in patients with stage 5 chronic kidney disease (CKD).	26037625
Traumatic injury	Altered Intercellular Communication	Imaging data were recorded for eight examinations: head (trauma, shunt), temporal bone, paranasal sinuses, chest (mass) and chest HRCT (high-resolution CT), and abdomen/pelvis (mass/inflammation).	26037714
Gastritis	Altered Intercellular Communication	The carriage of the C allele of IL-6 may lead a susceptibility to chronic gastric inflammation after contamination with H. pylori.	26039006
Inflammation, Fracture, Neoplasms	Altered Intercellular Communication	Axial, multiplanar, and 3D-volume-rendered images were reviewed by 3 reviewers for the property of the lesions (fracture, tumor, and tumor-like lesions or inflammation).	26039118
Inflammation	Altered Intercellular Communication	For the diagnosis of inflammation lesions, average accuracy was 100% for all the 3 image formats.	26039118
Inflammation, Fracture, Neoplasms	Altered Intercellular Communication	Interobserver agreement independence of imaging formats was high.Multiplanar and 3D-volume-rendered images were superior to axial images in diagnosis of fracture, tumor, and tumor-like lesions; however, for the evaluation of inflammation lesions, there were no difference by 3 image formats.	26039118
Inflammation, Endothelium	Altered Intercellular Communication	Valvular calcification occurs via ongoing endothelial injury associated with inflammation.	26039365
ARCN1 gene, Inflammation	Altered Intercellular Communication	IL-17A is central for neutrophilic inflammation and has been linked to COPD pathogenesis.	26039632
Injury of liver, Inflammation, Liver damage, Hepatitis	Altered Intercellular Communication	IL-1a may have important role as marker of both inflammation and hepatic injury, particularly in the course of hepatitis C. Results suggest that inflammatory and immune parameters, analyzed together can significantly contribute to the understanding and predicting of chronic liver damage.	26040073
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Inflammation and cell-mediated immune activation are attributed to the pathogenesis and pathophysiology in depression.	26041659
Inflammation, Depression, CTCAE	Altered Intercellular Communication	This indicated that the elevated neopterin levels may play a significant role in the pathology of depression and that the pathways leading to inflammation and cell-mediated immune activation warrant further exploration.	26041659
Inflammation, Atherosclerosis	Altered Intercellular Communication	These are key participants in the leukocyte adhesion and transmigration that play a major role in the inflammation and pathophysiology of CVD, including atherosclerosis.	26042828
Dehydration, Atherosclerosis	Altered Intercellular Communication	Elevated sodium and dehydration stimulate inflammatory signaling in endothelial cells and promote atherosclerosis.	26042828
Inflammation, Intradermal Route of Drug Administration	Altered Intercellular Communication	Inflammation, but not neurohormonal activation is associated with ID in systolic HF.	26043148
Ear Inflammation, Acute inflammation, Perforation (observation), Otitis Media with Effusion	Altered Intercellular Communication	Otitis media with effusion (OME) is characterized by the prolonged presence of fluid (longer than 12 weeks) of different viscosity in the middle ear, without perforation of the eardrum or signs of acute inflammation.	26043589
Inflammation, Atherosclerosis	Altered Intercellular Communication	Finally, LEx were not associated with aging, atherogenic risk factors, atherosclerosis, inflammation, or thrombogenesis.	26044080
Inflammation	Altered Intercellular Communication	Systemic inflammation appears to be an important contributor to the diseased microvascular network of these patients.	26044235
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	Helicobacter pylori (n = 154 vs 325, P < 0.001), neutrophil activity (n = 176 vs 367, P < 0.001), intestinal metaplasia (n = 35 vs 14, P < 0.001) and inflammation (n = 230 vs 386, P < 0.001) were present significantly more often in group II compared with group I.	26044795
Inflammation, Chronic venous insufficiency	Altered Intercellular Communication	Sulodexide suppresses inflammation in patients with chronic venous insufficiency.	26044841
Inflammation, Central visual impairment, Tissue injury, Venous Insufficiency	Altered Intercellular Communication	According to previously performed studies, inflammation plays a crucial role in vein wall and leg tissue injury related to chronic venous insufficiency (CVI) development.	26044841
Inflammation, Chronic Obstructive Airway Disease, Pathology	Altered Intercellular Communication	Data identify novel molecular targets for therapeutic strategies aimed at dampening inflammation in pathologies such as chronic obstructive pulmonary disease, in which reduced intracellular HDAC2 levels have been described.	26044852
HD Term Type, Inflammation	Altered Intercellular Communication	Systemic inflammation is highly prevalent in HD patients and is associated with ESA hyporesponsiveness.	26045064
HD Term Type, Inflammation	Altered Intercellular Communication	Further research is needed to test whether interventions that successfully decrease oxidative stress and inflammation in patients undergoing maintenance HD improve ESA responsiveness.	26045064
Inflammation, FAM126A gene	Altered Intercellular Communication	The dlDNA proportion can be regulated by inflammatory cytokines, suggesting an association among inflammation, increased production of HBV dlDNA and development of HCC.	26045139
Inflammation, Vitreous inflammatory cells	Altered Intercellular Communication	Both anterior segments were without inflammation, but fundoscopy showed mild vitreous inflammation and multiple inflammatory choroidal lesions.	26045521
Pain Distress Question, prostatitis	Altered Intercellular Communication	CD-163 correlated with symptoms (pain or discomfort) of prostatic inflammation.	26045748
prostatitis	Altered Intercellular Communication	The purpose of this study is to identify significant immune-system related for symptom of patients with prostatic inflammation in order to investigate the etiology of prostatic inflammation which may relate to potentially chronic prostatitis (CP).	26045748
Primary malignant neoplasm, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	We investigated the expression of immune system-related biomarkers such as Interleukin (IL) -6 (humoral immunity), CD-3 (T-lymphocyte), and CD-163 (macrophage) in prostate biopsy (PBx) specimens from patients with prostatic inflammation (without cancer) which had been neither clinically diagnosed benign prostatic hyperplasia nor chronic prostatitis.	26045748
Pain Distress Question, prostatitis	Altered Intercellular Communication	Our results showed CD-163 (macrophage) reflected pain or discomfort on NIH-CPSI scores (P=0.0389 and r=0.3307) in the patients with prostatic inflammation; however, the control patients had no significant correlation between symptom scores and those immune-related markers' expression.	26045748
Pain Distress Question, prostatitis	Altered Intercellular Communication	These results suggest that pain or discomfort related to macrophages in the relationship between immune-system and the symptom of prostatic inflammation.	26045748
Pain Distress Question, Lower Urinary Tract Symptoms, prostatitis	Altered Intercellular Communication	In conclusion, CD-163, related to immune-system (macrophage), correlated with symptoms (pain or discomfort) of prostatic inflammation and might represent a significant immune-system related biomarker for pain or LUTS score in potentially CP.	26045748
Inflammation, Abscess, Fasciitis	Altered Intercellular Communication	This case represents an unusual complication of a common disease and we should bear in mind that retroperitoneal inflammation and/or abscesses may cause necrotizing fasciitis through lumbar triangles.	26045863
Inflammation, Infection	Altered Intercellular Communication	Infections and inflammation of the lower limb skin, soft tissues, and vessels are more common than in other body regions.	26046245
Inflammation, Dysautonomia, Familial	Altered Intercellular Communication	In addition to accumulation of a-galactosidase A substrates, other mechanisms may be involved in FD pathophysiology, such as inflammation and oxidative stress.	26046974
Inflammation, Bronchiectasis, Fibrosis Assessment, Repeat, Lung diseases	Altered Intercellular Communication	Lung disease in cystic fibrosis (CF) involves excessive inflammation, repetitive infections and development of bronchiectasis.	26047144
Inflammation, Prostate carcinoma	Altered Intercellular Communication	We previously found that inflammation in benign prostate tissue is associated with an increased odds of prostate cancer, especially higher-grade disease.	26047319
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Our findings generally support the role of inflammation in the etiology of prostate cancer.	26047319
ACSM3 gene, Inflammation, Subarachnoid Hemorrhage, Aneurysm, Ruptured, Brain Injuries	Altered Intercellular Communication	Attempts to clarify mechanisms of early brain injury in subarachnoid hemorrhage (SAH) revealed a high-mobility group box 1 (HMGB1) protein involvement in sterile inflammation initiated by aneurysm rupture.	26047599
Inflammation	Altered Intercellular Communication	Low-tube-voltage 80 kVp neck CT provides increased enhancement of soft-tissue inflammation, CNR, raCNR, and improved abscess delineation in patients with PTA compared to standard 120 kVp acquisition while resulting in a significant reduction of radiation exposure.	26050533
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Diet and inflammation have been suggested to be important risk factors for colorectal cancer (CRC).	26050563
Ulcerative Colitis	Altered Intercellular Communication	Level of Fecal Calprotectin Correlates With Endoscopic and Histologic Inflammation and Identifies Patients With Mucosal Healing in Ulcerative Colitis.	26051392
HD Term Type, Inflammation	Altered Intercellular Communication	Our study suggests that R-S-Y-R-T could decrease chronic inflammation and increase the life quality in HD patients.	26051571
Inflammation, Endothelial dysfunction, Ischemic stroke	Altered Intercellular Communication	Thromboinflammatory molecules connect the prothrombotic state, endothelial dysfunction, and systemic/local inflammation in the acute phase of ischemic stroke.	26051664
Inflammation, Psoriasis	Altered Intercellular Communication	Nonattenuation corrected FDG-PET images may be useful and preferable to AC images in assessing skin inflammation in psoriasis.	26053710
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular Inflammation in the Setting of Concomitant Systemic Autoimmune Conditions in an Older Male Population.	26053887
Pain Distress Question, Irritation, Inflammation	Altered Intercellular Communication	PerioPatch(tm) is an approved device product that has been developed as an oral adhesive barrier for promoting healing in inflamed oral/gingival tissues and reducing pain, irritation, and the symptoms of inflammation.	26053922
Periodontitis, Periodontal Diseases	Altered Intercellular Communication	Periodontal disease (periodontitis) is a common inflammatory condition affecting the deep, supporting tissues around teeth.	26053922
Inflammation	Altered Intercellular Communication	MFAP5 is related to obesity-associated adipose tissue and extracellular matrix remodeling and inflammation.	26054006
Inflammation	Altered Intercellular Communication	Low-grade inflammation is involved in adipose tissue (AT) and extracellular matrix (ECM) remodeling and induces deposition of ECM proteins in AT.	26054006
Inflammation	Altered Intercellular Communication	Our results demonstrate that factors involving low-grade inflammation modulate MFAP5 expression and that the modified expression of MFAP5 may further regulate AT inflammation.	26054006
vascular inflammations, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Increased oxidative stress and vascular inflammation are implicated in increased cardiovascular disease (CVD) incidence with age.	26054376
Inflammation	Altered Intercellular Communication	Systemic inflammation as a predictor of clinical outcomes after lower extremity angioplasty/stenting.	26054584
Inflammation, Failure (biologic function)	Altered Intercellular Communication	Although the global influence of angioplasty/stenting on systemic inflammation was modest, circulating cytokine and monocyte genome analyses support a pattern of early inflammation that is associated with ultimate intervention success vs failure.	26054584
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Chronic stress and chronic low-grade inflammation are prominent risk factors for T2D development in pre-diabetic subjects.	26055228
Inflammation, Prediabetes syndrome, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	However, molecular mechanisms mediating effect of stress and inflammation on development of T2D from pre-diabetes remain unknown.	26055228
Inflammation, Prediabetes syndrome, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Our results provide further support of "kynurenine hypothesis of insulin resistance and its progression to T2D" that suggested that overproduction of diabetogenic KP metabolites, induced by chronic stress or chronic low-grade inflammation, is one of the mechanisms promoting development of T2D from pre-diabetes.	26055228
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Vascular endothelial inflammation and enhanced oxidative stress are important factors in the pathogenesis of obstructive sleep apnea syndrome (OSAS).	26055465
Schizophrenia, Rhabdomyositis, Tropical pyomyositis, Necrosis	Altered Intercellular Communication	Owing to serial increases (up to 1310 U/L) in serum creatine kinase and a history of local intramuscular paliperidone injections for management of schizophrenia, surgical exploration was performed and identified necrotising skeletal muscle inflammation and extensive fat necrosis with an organising abscess, consistent with pyomyositis.	26055607
Inflammation, Psoriasis	Altered Intercellular Communication	Leukocyte-derived koebnerisin (S100A15) and psoriasin (S100A7) are systemic mediators of inflammation in psoriasis.	26055798
Inflammation	Altered Intercellular Communication	In the skin, the antimicrobial proteins koebnerisin (S100A15) and psoriasin (S100A7) are overexpressed in the epidermis of psoriatic lesions and mediate inflammation as chemoattractants for immune cells.	26055798
Ulceration, CTCAE, Gastrointestinal mucositis	Altered Intercellular Communication	Ten patients with plasma cell-rich chronic inflammatory conditions of the oral mucosa were identified (seven--plasma cell mucositis and three--non-specific diffuse oral mucosal inflammation with ulceration).	26056156
Ulceration, CTCAE, Gastrointestinal mucositis	Altered Intercellular Communication	Ten patients with plasma cell-rich chronic inflammatory conditions of the oral mucosa were identified (seven--plasma cell mucositis and three--non-specific diffuse oral mucosal inflammation with ulceration).	26056156
vascular inflammations, Hypertension, CTCAE, Endothelial dysfunction	Altered Intercellular Communication	Soluble vascular cell adhesion molecule-1 (sVCAM-1) is associated with hypertension, vascular inflammation, and systemic endothelial dysfunction.	26056332
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Several studies have been performed to validate the association between depression and inflammation in haemodialysis patients.	26057312
HD Term Type, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Although IL-6 level was higher in HD compared to CAPD patients, the relationship between depression and presence of inflammation parametars were observed in CAPD, but not in HD patients.	26057312
Inflammation, Microvascular Angina	Altered Intercellular Communication	Does Inflammation Have a Role in the Pathogenesis of Cardiac Syndrome X?	26058672
Inflammation, Liver carcinoma	Altered Intercellular Communication	Imbalance in systemic inflammation and immune response following transarterial chemoembolization potentially increases metastatic risk in huge hepatocellular carcinoma.	26058874
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	Inflammation plays a critical role in tumor metastasis.	26058874
Liver carcinoma, Neoplasm Metastasis, FAM126A gene	Altered Intercellular Communication	However, few inflammation-related biomarkers are currently available to predict the risk of metastasis for advanced hepatocellular carcinoma (HCC).	26058874
Inflammation, Neoplasm Metastasis, FAM126A gene	Altered Intercellular Communication	Our findings suggest the potential contribution of treatment-related inflammation to metastasis in advanced HCC.	26058874
Inflammation	Altered Intercellular Communication	Intracranial delivery of the IL13-zetakine(+) CTL clones into the resection cavity of 3 patients with recurrent disease was well-tolerated, with manageable temporary brain inflammation.	26059190
Cancer of Urinary Tract, Cerebrovascular accident	Altered Intercellular Communication	In contrast, DRGs 14 (stroke), 79 (respiratory infections/ inflammations), and 320 (kidney/urinary infections) had a smaller reduction in dementia-associated adjusted odds ratio (0.41-0.46) for home discharge.	26059911
Inflammation, Metabolic Syndrome X, Refractory anemias, ETV3 wt Allele, Degenerative polyarthritis, Rheumatoid Arthritis	Altered Intercellular Communication	The purpose of the study was to examine whether rheumatoid arthritis (RA) patients have higher prevalence of metabolic syndrome (MetS) than osteoarthritis (OA) patients in association with a higher level of chronic systemic inflammation in rheumatoid arthritis.	26059944
Inflammation	Altered Intercellular Communication	Rebamipide improves chronic inflammation in the lesser curvature of the corpus after Helicobacter pylori eradication: a multicenter study.	26060821
Inflammation	Altered Intercellular Communication	Chronic inflammation affecting the lesser curvature of the corpus was significantly improved in the rebamipide group compared to in the untreated group (1.12 +- 0.08 versus 1.35 +- 0.08; P = 0.043).	26060821
Inflammation	Altered Intercellular Communication	Rebamipide treatment after H. pylori eradication alleviated chronic inflammation in the lesser curvature of the corpus compared to that in the untreated group.	26060821
Abscess, Inflammation	Altered Intercellular Communication	The initial pathology report of the excised specimen confirmed the presence of nonspecific abscesses and inflammation.	26061492
Inflammation, Tissue injury	Altered Intercellular Communication	Positive end-expiratory pressure (PEEP) improves gas exchange and respiratory mechanics, and it may decrease tissue injury and inflammation.	26061818
Intraocular inflammation	Altered Intercellular Communication	[Incidence of endogenous intraocular inflammation patients who visited Nippon Medical School Hospital during the 8 years from 2004 to 2012].	26062391
Intraocular inflammation	Altered Intercellular Communication	To report the clinical statistical analysis of patients with endogenous intraocular inflammation who visited Nippon Medical School Hospital during the 8 years from 2004 to 2012.	26062391
Intraocular inflammation	Altered Intercellular Communication	This retrospective study involved 759 new patients with endogenous intraocular inflammation who visited Nippon Medical School Hospital during the 8 years from April 2004 to April 2012.	26062391
Uveomeningoencephalitic Syndrome, Sarcoidosis, Scleritis, Intraocular inflammation	Altered Intercellular Communication	Sarcoidosis, scleritis and Vogt-Koyanagi-Harada disease were frequent intraocular inflammations in ophthalmologic patients at Nippon Medical School Hospital.	26062391
Granulomatous inflammation, GCA gene, Giant Cell Arteritis, Vasculitis, Takayasu Arteritis	Altered Intercellular Communication	Takayasu arteritis (TA) and giant cell arteritis (GCA) are large vessel vasculitides (LVV) that usually present as granulomatous inflammation in arterial walls.	26062541
Inflammation, Neoplasms	Altered Intercellular Communication	Time-Course Changes of Cardiac-Specific Inflammation in a Patient With Left Ventricular Calcified Amorphous Tumor.	26062949
Autoimmune Diseases, Rheumatoid Arthritis, Have Autoimmune or Inflammatory Condition, Refractory anemias	Altered Intercellular Communication	In autoimmune diseases such as rheumatoid arthritis (RA), regulatory T cells (Tregs) fail to constrain autoimmune inflammation; however, the reasons for this are unclear.	26062995
Hypertension, CTCAE, Hepatitis, Liver Cirrhosis	Altered Intercellular Communication	Abnormally high plasma levels of Nogo-B are associated with hepatic cirrhosis and Child-Pugh score, but not correlated with the grade of liver inflammation or portal hypertension.	26063954
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	A skeletal muscle biopsy demonstrated vacuolar myopathic changes (acid phosphatase negative) accompanied by focal endomysial fibrosis and chronic inflammation.	26067541
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Diabetes mellitus type 2 (DMT2) is accompanied by systemic low-grade inflammation with elevated levels of interleukin-6 (IL-6), which is encoded by a gene (IL-6) previously shown to be regulated by DNA methylation.	26067576
Interstitial Fibrosis Assessment, Interstitial inflammation, Tubular atrophy	Altered Intercellular Communication	Those of interstitial fibrosis and tubular atrophy classes 0, 1, 2, and 3 were 0, 7, 9, and 11, and those of interstitial inflammation classes 0, 1, and 2 were 0, 3, and 4, respectively.	26067713
Inflammation	Altered Intercellular Communication	Nuclear factor kappa B (NF-kB) pathway proteins play an important role in modulating inflammation and other carcinogenic processes.	26068031
Colon Carcinoma, Inflammation, Neoplasms	Altered Intercellular Communication	Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis.	26068398
Orbital Pseudotumor	Altered Intercellular Communication	Slides were reviewed by a masked ocular pathologist who evaluated the level of orbital inflammation.	26068557
Granulomatous inflammation, Inflammation	Altered Intercellular Communication	Histopathology demonstrated foci of granulomatous inflammation in the orbit of the patient and similar inflammation in the rat orbits injected with retrobulbar alcohol.	26068557
Inflammation, Orbital Pseudotumor	Altered Intercellular Communication	Our findings in this preclinical pilot study suggest that retrobulbar alcohol injections incite significant orbital inflammation, whereas retrobulbar chlorpromazine induces little or no inflammation.	26068557
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Low-grade inflammation, as measured by hs-CRP level, may have an important role in the development of diabetes among African Americans with a lesser degree of insulin resistance.	26068864
Carpal Tunnel Syndrome, Inflammation	Altered Intercellular Communication	Carpal tunnel syndrome (CTS), can also occur in BD patients secondary to inflammation in the connective tissues, vessels, and tendons, as well as nerve involvement in BD itself.	26069125
Carpal Tunnel Syndrome, Inflammation	Altered Intercellular Communication	CTS can occur as a result of the inflammation associated with BD and can also be the presenting symptom of nerve involvement in BD.	26069125
Inflammation	Altered Intercellular Communication	Vascular access (VA) devices may contribute to chronic inflammation in hemodialysis (HD).	26070095
Urinary tract infection, prostatitis	Altered Intercellular Communication	In our study, suprapubic trocar placement (11/12), chronic prostatic inflammation (9/12), previous UTI (3/12) and extended resection (2/12) were overrepresented.	26070659
Inflammation, Restless Legs Syndrome	Altered Intercellular Communication	Association of restless legs syndrome with oxidative stress and inflammation in patients undergoing hemodialysis.	26070856
Inflammation, Dysplasia of anus	Altered Intercellular Communication	Morphologic evaluation of anal dysplasia remains problematic, especially in cases with limited biopsy samples or obscuring inflammation.	26071469
Prostate carcinoma, prostatitis	Altered Intercellular Communication	Is histological prostate inflammation in an initial prostate biopsy a predictor of prostate cancer on repeat biopsy?	26071871
Inflammation, Prostate carcinoma	Altered Intercellular Communication	To investigate whether histological inflammation detected in an initial prostate biopsy can predict the risk of prostate cancer on a repeat biopsy.	26071871
Aggressive behavior, prostatitis, Primary malignant neoplasm	Altered Intercellular Communication	Prostate inflammation grade (p = 0.005) and aggressiveness (p = 0.001) in the initial biopsy were significantly different between the cancer and noncancer groups.	26071871
Prostate carcinoma	Altered Intercellular Communication	Factors associated with the risk of prostate cancer at the repeat biopsy were age [odds ratio (OR) 1.08; 95 % confidence interval (CI) 1.03-1.14], prostate-specific antigen density (OR 24.30; 95 % CI 9.3-62.9), prostate-specific antigen velocity (OR 1.05; 95 % CI 1.01-1.09), and inflammation aggressiveness (OR 0.05; 95 % CI 0.01-0.27).	26071871
Inflammation, Biliary calculi, Fibrosis Assessment, Pancreas, Obstruction of biliary tree, Calcinosis, Phlebitis, Cortical irregularity	Altered Intercellular Communication	Pathologically, the average inflammatory mass diameter was 3.8 +- 3.3 cm, biliary obstruction occurred in 36 cases, gall stones in 70 cases, calcification in 88 cases, ductal dilatation in 61 cases, side branch dilatation in 32 cases, ductal irregularity in 10 cases, lymphocytic inflammation in 23 cases, obliterative phlebitis in 14 cases, extra pancreatic lesion in 19 cases and fibrosis in 142 cases.	26072078
Sepsis, Communicable Diseases	Altered Intercellular Communication	Sepsis is the syndrome of body-wide inflammation triggered by infection and is a major public health problem.	26072206
Communicable Diseases, Inflammation, Hypersensitivity	Altered Intercellular Communication	It may cause some adverse effects such as local inflammation, infection, and allergic reactions on the skin and even systemic adverse effects such as sarcoidal reactions.	26073118
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Chinese patients with obesity and type II diabetes have significantly lower plasma CTRP-3 concentrations than healthy subjects do, and plasma CTRP-3 is strongly associated with glucose and lipid metabolism, chronic inflammation, and insulin resistance.	26073386
Inflammation	Altered Intercellular Communication	Runners with exercise-induced high blood pressure have recently been reported to exhibit higher levels of cardiac markers, vasoconstrictors, and inflammation.	26073606
Inflammation, Rupture	Altered Intercellular Communication	Inflammation is a key factor in the development of plaque rupture and acute cardiovascular events.	26074318
Inflammation, Hypoxia, Colorectal Carcinoma, Neoplasms	Altered Intercellular Communication	Summarizing, our results link Nampt/PBEF/visfatin with tumor metastatic potential and point at inflammation and hypoxia as key inducers of its upregulation in CRC.	26075243
Conjunctivitis	Altered Intercellular Communication	A third patient presented with nodular conjunctival inflammation, which initially had been treated with topical ciprofloxacin and corticosteroids without improvement.	26075451
Inflammation, Inflammatory disorder	Altered Intercellular Communication	NF-kB, a central regulator of inflammation, is involved in various inflammatory diseases.	26075620
Inflammation	Altered Intercellular Communication	The interaction between fatness, fitness, and C-reactive protein (CRP) in adolescents is not well characterized but may be important to prevent low grade inflammation.	26075745
Inflammation, Primary malignant neoplasm, Metabolic Syndrome X, Cardiovascular Diseases, Diabetes Mellitus	Altered Intercellular Communication	The role of Clusterin in attenuation of inflammation and reverse cholesterol transfer makes this molecule a potential candidate as a marker for cancer, cardiovascular disease, diabetes mellitus, and metabolic syndrome.	26076476
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	The Relationship Among Perceived Stress, Symptoms, and Inflammation in Persons With Inflammatory Bowel Disease.	26077178
Gastrointestinal inflammation	Altered Intercellular Communication	The association between perceived stress and gastrointestinal inflammation is not well described.	26077178
Inflammation, Gastrointestinal inflammation	Altered Intercellular Communication	Intestinal inflammation was determined through measurement of fecal calprotectin (FCAL), with a level exceeding 250 mg/g indicating significant inflammation.	26077178
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	There was no significant association between perceived stress and intestinal inflammation for either CD or UC.	26077178
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Active symptoms (MIBDI <=3) were associated with intestinal inflammation in UC (odds ratio (OR) 3.94, 95% CI 1.65-9.43), but not in CD (OR 0.98, 95% CI 0.51-1.88).	26077178
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Symptomatic disease activity was unrelated to intestinal inflammation in CD and only weakly associated in UC.	26077178
Gastrointestinal inflammation	Altered Intercellular Communication	Although there was a strong relationship between perceived stress and gastrointestinal symptoms, perceived stress was unrelated to concurrent intestinal inflammation.	26077178
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Longitudinal investigation is required to determine the directionality of the relationship between perceived stress, inflammation, and symptoms in IBD.	26077178
Inflammation, Non-alcoholic Fatty Liver Disease, Psoriasis	Altered Intercellular Communication	Nonalcoholic fatty liver disease, spleen and psoriasis: New aspects of low-grade chronic inflammation.	26078565
Inflammation, Atherosclerosis	Altered Intercellular Communication	Intercellular adhesion molecule-1 (ICAM-1) displays an important role in the development of the inflammation reaction and atherosclerosis.	26078712
Inflammation, Primary malignant neoplasm, Breast Carcinoma	Altered Intercellular Communication	Breast cancer is the most common cancer among women, and both low-grade inflammation and cathepsins might have important roles in breast cancer.	26079659
Inflammation, Data Type -Character	Altered Intercellular Communication	Clinical symptoms (Harvey-Bradshaw Index [HBI]), disease character, serological markers of inflammation [C-reactive protein], and endoscopic evaluation were collected and reviewed by two independent IBD-specialty physicians.	26079723
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The severity of inflammation at onset of ulcerative colitis is not associated with IBS-like symptoms during clinical remission.	26079726
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The severity and extent of inflammation at onset of UC do not seem to affect the development of IBS-like symptoms in UC patients during clinical remission.	26079726
Inflammation	Altered Intercellular Communication	This technique could avoid autogenous bone grafting or permanent alloplastic implantation, which may cause a foreign body reaction, chronic inflammation, and migration.	26080197
Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Diagnosis of Gorham-Stout can only be made after excluding other common causes of bony resorption such as those caused by infection, inflammation, malignancy, and endocrine.	26080240
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Macrophage and dendritic cell subsets in IBD: ALDH+ cells are reduced in colon tissue of patients with ulcerative colitis regardless of inflammation.	26080709
Cardiovascular Diseases	Altered Intercellular Communication	Almonds reduce cardiovascular disease risk via cholesterol reduction, anti-inflammation, glucoregulation, and antioxidation.	26080804
Inflammation, Feeling calm	Altered Intercellular Communication	A randomized, controlled, crossover trial was conducted in Boston, MA to test whether as compared to a control NCEP Step 1 diet absent nuts (CON), incorporation of almonds (85 g/day) into the CON diet (ALM) would improve vascular function and inflammation.	26080804
Barrett Esophagus, Adenocarcinoma Of Esophagus	Altered Intercellular Communication	We also evaluated expression in the precursor lesion of esophageal adenocarcinoma, Barrett's esophagus, which emerges following gastric reflux-induced esophageal inflammation, and found PD-L2 expression in Barrett's esophagus but not in non-Barrett's esophagus esophagitis.	26081225
Human papilloma virus infection, Primary malignant neoplasm, Uterine Cervicitis, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	The HPV infection rates for the patients with cervical inflammation, CIN, and cancer were 18.18%, 64.71%, and 100%, respectively.	26081269
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation and atherosclerosis are associated with many age-related conditions and atherosclerosis has been associated with olfactory decline in middle-aged adults.	26082178
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	To study the expression pattern of microRNAs and mRNAs related to inflammation in T2D monocytes.	26083362
muscle mass, Myositis	Altered Intercellular Communication	In view of the lack of accretion of muscle mass in response to the alpine skiing intervention, we hypothesize that local muscle inflammation and oxidative stress may have blunted the anabolic response to training and promoted muscle breakdown in this elderly post-TKA population.	26083700
Arthritis	Altered Intercellular Communication	The up-regulated CD64(+) monocytes seem to be have an important role in psoriatic joint inflammation.	26084203
vascular inflammations, Vessel perforation	Altered Intercellular Communication	The e4 allele is considered to promote Ab deposition on the vessel wall, and e2 is speculated to trigger vessel ruptures or vascular inflammation.	26084230
vascular inflammations, Calcification of coronary artery	Altered Intercellular Communication	Elevated serum uric acid is associated with vascular inflammation but not coronary artery calcification in the healthy octogenarians: the Brazilian study on healthy aging.	26084248
Inflammation, Calcification of coronary artery, SLC25A20 gene	Altered Intercellular Communication	We evaluated the association of SUA, highly sensitive C-reactive protein (hs-CRP, a marker of vascular and systemic inflammation), and coronary artery calcification (CAC, a marker of subclinical CVD) in a cohort of Brazilian octogenarians (>=80 years) free from known clinical CVD.	26084248
vascular inflammations, Coronary Arteriosclerosis, SLC25A20 gene	Altered Intercellular Communication	In the healthy octogenarians, higher SUA levels are associated with vascular inflammation (hs-CRP) but not with coronary atherosclerosis (CAC); markers for the subclinical CVD.	26084248
Sepsis, vascular inflammations, Cardiovascular Diseases	Altered Intercellular Communication	Our results provide insight into the control of vascular inflammation by IL-35 and suggest that IL-35 is an attractive novel therapeutic reagent for sepsis and cardiovascular diseases.	26085094
Inflammation, Apoptosis, Impaired Circulation	Altered Intercellular Communication	The intrinsic risk factors of rotator cuff disease (RCD) include degeneration, inflammation, oxidative stress, and circulation impairment.	26085191
Inflammation	Altered Intercellular Communication	However, mini-implants may cause injury to adjacent teeth or anatomical structures and may lead to tissue inflammation.	26085484
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	First step in the development of an ultrasound joint inflammation score for rheumatoid arthritis using a data-driven approach.	26085490
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To develop and validate candidate sets of joints and tendons for assessment of ultrasound (US) joint inflammation in rheumatoid arthritis (RA).	26085490
Inflammation	Altered Intercellular Communication	Neopterin has been considered as an important marker of cellular inflammation.	26086324
Communicable Diseases, Inflammation	Altered Intercellular Communication	Numerous studies have been suggested that even in the absence of acute infection ageing associated with chronic low-grade inflammation and the underlying cause of this process may be an immunosenescence as well as shifts production of cytokines levels.	26087730
Hyperlipidemia	Altered Intercellular Communication	It is well-known that permanent stimulation of immune responses may lead to hyperlipidemia that, in its turn, may evoke immune disturbances and affect the auto-inflammation processes.	26087731
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	However, the initiation of inflammation and progression to IBD pathogenesis in a given individual is poorly understood.	26088200
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	The patient presented with a severe onset of disease, which was first suspected to be ulcerative colitis on outpatient examination and was later corrected to IBD with Crohn's-like features due to high systemic inflammation, mixed lymphocytic-granulocytic infiltrates in gastric biopsies, and further characteristics suggestive of Crohn's disease.	26088200
Inflammation, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	We investigated the correlation between the red cell distribution width (RDW) and RDW-to-platelet ratio (RPR) with the degree of inflammation and fibrosis in chronic hepatitis patients with different etiologies and in native and transplanted liver.	26088296
Fibrosis Assessment, Hepatitis, Liver Cirrhosis, End Stage Liver Disease	Altered Intercellular Communication	The correlation among the RDW, RPR, and model for end-stage liver disease (MELD) score with the degree of liver inflammation, fibrosis, and cirrhosis in separate groups of native and transplanted liver was calculated.	26088296
Symptoms, Inflammatory abnormality of the eye	Altered Intercellular Communication	In vivo detection of clinically non-apparent ocular surface inflammation in patients with meibomian gland dysfunction-associated refractory dry eye symptoms: a pilot study.	26088680
Symptoms, Keratitis, Meibomian gland dysfunction	Altered Intercellular Communication	The utility of in vivo confocal microscopy (IVCM) in the investigation of palpebral conjunctival and corneal inflammation in patients with meibomian gland dysfunction (MGD)-associated refractory dry eye symptoms following gland expression, despite objective clinical improvement.	26088680
Inflammation	Altered Intercellular Communication	MGD-associated refractory symptoms and the symptom-sign disparity may be explained by clinically non-apparent, active inflammation of the palpebral conjunctiva as detected by IVCM.	26088680
Airway structure	Altered Intercellular Communication	qPCR identifies a significant number of patients with potentially bacteria-associated neutrophilic airway inflammation and disease that are not identified by traditional culture-based methods.	26089657
Communicable Diseases, Inflammation, "Grisels syndrome", Subluxation of atlantoaxial joint	Altered Intercellular Communication	Grisel's syndrome is a nontraumatic atlantoaxial subluxation, usually secondary of an infection or an inflammation at the head and neck area, or after surgery in the same area.	26090020
Degenerative polyarthritis, Inflammation, Pain Distress Question	Altered Intercellular Communication	OA is closely associated with angiogenesis and the inhibition of angiogenesis presents a novel therapeutic approach to reduce inflammation and pain in OA.	26090403
Inflammation	Altered Intercellular Communication	Hr-anxA1 may offer pharmacological means to treat chronic atherogenesis by reducing FPR-2 dependent neutrophil rolling and adhesion to activated endothelial cells and by reducing total plaque inflammation.	26090792
Inflammation, Dental Plaque	Altered Intercellular Communication	Interestingly, inflammation was significantly correlated with neovessel formation (r=0.43, p=0.0008), hemosiderin spots (r=0.62, p<0.0001), and IPH (r=0.349, p=0.0097), suggesting that inflammation may be a key factor in plaque vulnerability.	26090834
Inflammation, Carotid Stenosis	Altered Intercellular Communication	Communication of inwardly projecting neovessels with the lumen and inflammation synergistically contribute to IPH and symptomatic presentations in patients with carotid stenosis and are more specific than the vasa vasorum.	26090834
Inflammation	Altered Intercellular Communication	This condition could be a new therapeutic target, and regression of luminal neovessel sprouting and inflammation may help to prevent IPH development and a symptomatic presentation.	26090834
Necrotizing granulomatous inflammation, Pseudolymphoma, Malignant Neoplasms	Altered Intercellular Communication	The most common lymph node pathologies in CHBAH are malignancies, nonspecific reactive lymphoid hyperplasia, necrotizing granulomatous inflammation and HIV reactive nodes.	26091519
Inflammation, Mucous Membrane	Altered Intercellular Communication	It is well established that secondary scar formation caused by inflammation and mucosal injury are the main mechanisms by which stenosis occurs.	26091844
Cessation of life, Hypertrophy	Altered Intercellular Communication	Progressive cardiac remodelling was stimulated through hypertrophy and death of individual cardiomyocytes, with infiltration, proliferation and activation of fibroblast and inflammatory cells, leading to increased angiogenic and inflammatory signalling.	26092119
selenium, Epilepsy, Status Epilepticus	Altered Intercellular Communication	Inflammation-related epilepsy is increasingly recognized; however, studies on status epilepticus (SE) are very infrequent.	26092915
Inflammatory abnormality of the eye	Altered Intercellular Communication	Outcome measures include ocular surface inflammation, fornix reformation, and restoration of ocular motility.	26093286
Periodontal Diseases	Altered Intercellular Communication	Evidence exists that periodontal disease treatment may reduce inflammatory mediators in gingival crevicular fluid (GCF) and the risk of inflammation-associated pregnancy complications.	26093363
Inflammation, Urethral Stenosis	Altered Intercellular Communication	Urethral strictures in transplant patients may arise due to many factors, such as repetitive urethral catheterization and inflammation.	26093713
Inflammation, Carotid artery calcification, Diabetes Mellitus	Altered Intercellular Communication	Diabetes modifies the relationships among carotid plaque calcification, composition and inflammation.	26093886
Inflammation, Calcinosis, Dental Plaque, Diabetes Mellitus	Altered Intercellular Communication	Though plaque composition and calcification were not quantitatively affected, diabetes modified the relationships between plaque calcium, composition and inflammation.	26093886
Inflammation, Lymphedema	Altered Intercellular Communication	The attack frequency of inflammation of lymphatic vessels, the stage of lymphedema disease, and leg circumference were observed before and after the care.	26094422
Inflammation, Chronic liver disease	Altered Intercellular Communication	In 3 patients, liver biopsy was performed and revealed signs of inflammation and chronic liver disease, as enlarged densely infiltrated portal tracts with mild-to-moderate interface hepatitis.	26094550
Paresis, Myositis, CTCAE 5.0, Myositis	Altered Intercellular Communication	Sporadic inclusion body myositis (sIBM) is a systemic disease that is characterized by substantial skeletal muscle weakness and muscle inflammation, leading to impaired physical function.	26095885
Brain Injuries, Ischemic stroke	Altered Intercellular Communication	Nine previously reported stroke-associated miRNAs (miR-21, miR-23a, miR-29b, miR-124, miR-145, miR-210, miR-221, miR-223 and miR-483-5p) were measured by quantitative real time-PCR, and plasma high-sensitivity C-reactive protein (hs-CRP) and serum interleukin 6 (IL-6), the pro-inflammation markers in brain injury, were examined by enzyme-linked immunosorbent assay in 146 acute ischemic stroke patients and 96 healthy blood donors.	26096228
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	We aimed to investigate the importance of neutrophil-lymphocyte ratio (NLR) in patients with chronic obstructive pulmonary disease (COPD) for identifying the severity of inflammation and recognition of acute exacerbation.	26096858
ARCN1 gene, Inflammation	Altered Intercellular Communication	Elevated NLR can be used as a marker similar to CRP, WBC and ESR, in the determination of increased inflammation in acutely exacerbated COPD.	26096858
Inflammation, bone destruction, Arthritis, Collagen-Induced	Altered Intercellular Communication	In vivo effects of aGalCer-stimulated NKT cells on inflammation and bone destruction were determined in mice with collagen-induced arthritis.	26097058
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	This study suggests that TV viewing was unfavourably associated with several markers of inflammation and endothelial dysfunction.	26097139
Inflammation, Kit Ligand, human, atherosclerotic, Atherosclerosis	Altered Intercellular Communication	An accumulating body of evidence suggests that slow coronary flow (SCF) phenomenon seems to be an early-form of atherosclerosis and low-grade inflammation plays a major role in the atherosclerotic vascular processes.	26097597
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Inflammation is now believed to be responsible for coronary heart disease (CHD).	26098632
Ear discharge	Altered Intercellular Communication	In the article we described a case of 22 year old, mentally impairment women with bilateral otorrhea, in the past treated for external ear canal inflammation.	26098654
Pneumonitis	Altered Intercellular Communication	The microbiomes of humans are associated with liver and lung inflammation.	26099252
Inflammation, Primary malignant neoplasm, Carcinogenesis	Altered Intercellular Communication	Chronic inflammation, due to the disease itself, generates a microenvironment able to promote cancer development, but it is still controversial whether immunosuppressive therapy may contribute to carcinogenesis.	26099279
Pain Distress Question, Inflammation	Altered Intercellular Communication	Metallosis as a cause of pain and inflammation in a patient with a knee replacement: A case description.	26099454
Communicable Diseases, Inflammation	Altered Intercellular Communication	As well as standard diagnostic procedures, patients will undergo whole body PET CT scan to localise infection or inflammation.	26101020
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	T, B, and NKT Cells in Systemic Inflammation in Obstructive Sleep Apnoea.	26101459
Inflammation, Osage language	Altered Intercellular Communication	The grade of OSA complication score correlated with systemic inflammation markers and the proportion of B cells.	26101459
Iron-Refractory Iron Deficiency Anemia, Inflammation, Leukocytosis	Altered Intercellular Communication	Laboratory findings revealed inflammation with an increased C-reactive protein level (127 mg/L [1209 nmol/L]), leukocytosis (13 800/mm(3)), and microcytic anemia (hemoglobin level, 7.2 g/dL).	26101924
Prostatic Intraepithelial Neoplasias, Interstitial inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Of the remaining 13 patients, 6 were found to be histologically positive for Benign Prostatic Hypertrophy and 7 Chronic Interstitial Inflammation or High Grade Prostatic Intraepithelial Neoplasia.	26102053
Inflammation, Peripheral vascular alteration	Altered Intercellular Communication	12 (12/34) patients found to have no peripheral alterations in their prostate on 3T MRSI, none were positive for ADK or inflammation on histology.	26102053
Inflammation, Bone necrosis	Altered Intercellular Communication	Focal bone necrosis and inflammation were infrequent MRI findings.	26102409
Inflammation, Data types - Address	Altered Intercellular Communication	There is relatively little information about inflammation in the DS brain and how the genetics of DS may alter inflammatory responses and modify the course of AD pathogenesis in this disorder.	26103884
Inflammation, Intestinal Diseases	Altered Intercellular Communication	Environmental enteropathy is subclinical inflammation of the upper gastrointestinal tract associated with reduced linear growth in developing countries.	26103960
Gastrointestinal inflammation, Intestinal Diseases	Altered Intercellular Communication	Serum endotoxin core antibody (EndoCab) concentration is a potential indicator of intestinal inflammation and integrity, and thus may be useful to predict environmental enteropathy.	26103960
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	The reported results support the role of Mediterranean diet as a promising dietary tool for the primary prevention of diabetes, by attenuating inflammation and fostering total antioxidant capacity.	26104243
Inflammation, Metabolic Diseases	Altered Intercellular Communication	This dietary pattern may have therapeutic potential for many cardiometabolic disorders associated with inflammation and/or oxidative stress.	26104243
Erythema Multiforme, Hyperglycemia, Edema, Hyponatremia, DLST wt Allele, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The DLTs included mucosal inflammation, hyponatremia, face edema, erythema multiforme, and hyperglycemia.	26104654
Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Non-transferrin-bound iron is associated with biomarkers of oxidative stress, inflammation and endothelial dysfunction in type 2 diabetes.	26104728
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Fenofibrate reduces inflammation in obese patients with or without type 2 diabetes mellitus via sirtuin 1/fetuin A axis.	26105582
Inflammation, Granuloma	Altered Intercellular Communication	Histopathology of the biopsy collected from the left thigh upper ulcer and occipital nodule both demonstrated chronic inflammation with granuloma formation and yeast-like elements.	26105618
Hair follicle structure, Perifolliculitis, Keratinization, function	Altered Intercellular Communication	The presence of D. folliculorum was strongly associated with hair follicle duct dilatation and hyperkeratinization and with perifollicular nongranulomatous inflammation (p = 0.00).	26108058
Inflammation, Keratinization, function	Altered Intercellular Communication	Hair follicle duct dilatation, hyperkeratinization, and perifollicular inflammation were also independently associated with chalazia (p = 0.040 and 0.031, respectively).	26108058
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	Levels of high-sensitivity C-reactive protein (hs-CRP) and adiponectin, reflecting chronic inflammation, are associated with cardiovascular disease in type 2 diabetes.	26109470
Inflammatory abnormality of the eye, Dry Eye Syndromes	Altered Intercellular Communication	Subconjunctival injection of 100 mL 25 mg/mL bevacizumab is a safe and efficient treatment for ocular surface inflammation of dry eye disease.	26109847
Inflammation	Altered Intercellular Communication	Ecor-LDC inhibitors other than lysine analogs may maintain sufficient lysine levels and attachment integrity to prevent periodontal inflammation.	26110450
Vasculitis, Takayasu Arteritis	Altered Intercellular Communication	Takayasu arteritis is a rare disease that expresses chronic, large vessel inflammation.	26110486
Inflammation, Synovial Hypertrophy, Hydrarthrosis, Refractory anemias, Erosion of bone, Enthesitis, Tenosynovitis	Altered Intercellular Communication	Among RA patients, 82 (67.21%) were diagnosed with joint effusion, 78 (63.93%) were synovial thickening and 59 (48.36%) were bone erosion, while no tenosynovitis, soft tissue inflammation or enthesitis was found.	26110744
PROS1 gene, Inflammation, Synovial Hypertrophy, Hydrarthrosis, Erosion of bone, Enthesitis, Tenosynovitis	Altered Intercellular Communication	However, among the patients with PsA, 75 (60.97%) were diagnosed with joint effusion, 68 (55.28%) were synovial thickening, 71 (57.72%) were bone erosion, 71 (57.72%) were tenosynovitis, 44 (35.77%) were soft tissue inflammation and 39 (31.70%) were enthesitis.	26110744
PROS1 gene, Inflammation, Enthesitis	Altered Intercellular Communication	HFU proved valuable in detecting soft tissue inflammation and enthesitis in the fingers of PsA patients.	26110744
Inflammation, moisture	Altered Intercellular Communication	To resolve these clinical challenges, it is essential clinicians implement the TIME framework (tissue, inflammation/infection, moisture, edge of wound) as a model of effective wound bed preparation.	26110987
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Immunomodulation by interleukin-33 is protective in stroke through modulation of inflammation.	26111431
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Cerebral stroke induces massive Th1-shifted inflammation both in the brain and the periphery, contributing to the outcome of stroke.	26111431
Multiple Organ Failure, Inflammation	Altered Intercellular Communication	OPN concentrations were related to disease severity and significantly correlated with established prognosis scores and classical as well as experimental markers of inflammation and multi-organ failure.	26111529
Inflammation, Postoperative Period	Altered Intercellular Communication	The rim sign was thought to be the result of reactive inflammation in the hepatic tissue adjacent to a postoperative abscess within the gallbladder fossa.	26111711
Myocarditis, Complete atrioventricular block, Cardiac sarcoidosis, Heart Block	Altered Intercellular Communication	Complete heart block (CHB) caused by myocardial inflammation is a serious consequence of cardiac sarcoidosis (CS) that requires early diagnosis for effective anti-inflammatory treatment.	26111805
Myocardial fibrosis, Myocarditis	Altered Intercellular Communication	We defined abnormal (18)F-FDG uptake on (18)F-FDG PET and increased T2-weighted signal on cardiac MRI as signs of myocardial inflammation and delayed enhancement (DE) on cardiac MRI as a sign of myocardial fibrosis.	26111805
Inflammation, Complete atrioventricular block	Altered Intercellular Communication	Focal inflammation in the interventricular septum was associated with CHB and might predict recovery from CHB after corticosteroids if it coexists with preserved wall thickness.	26111805
Inflammation, Ductal Carcinoma	Altered Intercellular Communication	Dense chronic inflammation surrounding ductal carcinoma in situ was associated with a high score (P = 0.034).All 13 cases with PR >= 90%, <= 1 mitotic figure and absence of dense chronic inflammation around ductal carcinoma in situ had a low score (100% specificity).	26111975
Inflammation, Ductal Carcinoma	Altered Intercellular Communication	A low score was not observed in any case with at least two of the following--negative PR, >1 mitotic figure, and/or presence of dense chronic inflammation around ductal carcinoma in situ (100% specificity).	26111975
Arterial calcification, Cerebrovascular accident, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	Elevated fibroblast growth factor 23 (FGF23), a hormone that regulates phosphate homeostasis, has been associated with mortality, cardiovascular events, and stroke, and to arterial calcification in chronic kidney disease, but its role in atherosclerosis is unclear and population-based studies are lacking.	26112008
Communicable Diseases, Inflammation, Skin irritation	Altered Intercellular Communication	There were no complications such as skin irritation and wound infection, except for 1 case of chronic inflammation.	26112405
Asthma, Bronchitis	Altered Intercellular Communication	Exhaled breath temperature (EBT) has recently been proposed as a noninvasive marker of bronchial inflammation in patients with asthma.	26113222
Asthma, Bronchial Obstruction, Bronchitis	Altered Intercellular Communication	We performed a comprehensive study to determine whether EBT is related to asthma control, disease severity, bronchial obstruction, or bronchial inflammation.	26113222
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Inflammation triggered by alarmins plays a role in NSCLC pathogenesis.	26113410
Inflammation	Altered Intercellular Communication	Inflammation plays an important role in the pathophysiological process after carotid artery stenting (CAS).	26113783
Cessation of life, Inflammation	Altered Intercellular Communication	Thus, the lysosomal galectin puncta assay opens up new possibilities to study LMP in cell death and its role in other cellular processes such as autophagy, senescence, aging, and inflammation.	26114578
Inflammation, Postoperative infection	Altered Intercellular Communication	Dynamics of inflammation biomarkers C-reactive protein, leukocytes, neutrophils, and CD64 on neutrophils before and after major surgical procedures to recognize potential postoperative infection.	26114621
Inflammation	Altered Intercellular Communication	Operation time was significantly shorter (P = .0007), while immediate postoperative inflammation was significantly more severe (P = .001), in the iris fixation than in the scleral fixation group.	26116261
Astigmatism, Acute inflammation	Altered Intercellular Communication	Although operation time was shorter for iris fixation, it had several disadvantages, including induced astigmatism, immediate postoperative inflammation, earlier recurrence, and less stable refraction.	26116261
Fish-Eye Disease, Inflammation, Cytokeratin	Altered Intercellular Communication	Inflammation (ie, conjunctival injection, presence of keratic precipitates and intraocular signs) at the time of surgery for patients with FED was significant for developing rejection: 3.5 times greater compared with those with no inflammation (P = .02).	26116262
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are associated with increased airway and systemic inflammation.	26116425
Airway structure	Altered Intercellular Communication	There is evidence that erdosteine accelerates recovery from AECOPD by reducing airway inflammation.	26116425
Renal Insufficiency	Altered Intercellular Communication	Corrected Neutrophil Gelatinase-Associated Lipocalin (NGAL) Level Adjusted by the Scoring System of an Inflammation Index for Screening Renal Dysfunction in Patients with Systemic Inflammation.	26116587
Renal Insufficiency, Inflammation	Altered Intercellular Communication	This study investigated the use of corrected neutrophil gelatinase-associated lipocalin (cNGAL) values to screen renal dysfunction in patients with systemic inflammation.	26116587
Renal Insufficiency, Inflammation	Altered Intercellular Communication	A measurement of cNGAL may provide helpful information for assessing patients with renal impairment, particularly in association with systemic inflammation.	26116587
Inflammation, Endothelial dysfunction, Intermittent Claudication	Altered Intercellular Communication	Increased oxidative stress and inflammation contribute to impaired walking capacity and endothelial dysfunction in patients with intermittent claudication (IC).	26116711
Unknown (origin) (qualifier value), Inflammation	Altered Intercellular Communication	Expression of IL-18 was statistically higher in the aqueous of patients with HLA-B27 associated AAU in comparison to either idiopathic AAU or controls, but this may reflect greater inflammation in this patient group.	26116905
Inflammation	Altered Intercellular Communication	The specific signature of inflammation may potentially be useful in developing new future therapies for AAU.	26116905
Minimal Disseminated Disease, Depressive disorder, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Major depressive disorder (MDD) is a common consequence of interferon alpha (IFNa) treatment and important supporting evidence of a role of inflammation in the aetiology of depression.	26117091
palladium, Inflammation	Altered Intercellular Communication	Increased FA in the SN in PD indicates gliosis and inflammation in the nuclei, but possibly also intrusion of surrounding fibres into the shrinking structure.	26118635
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Pentraxin-2 (PTX-2), a serum protein, inhibits inflammation and fibrosis, and recombinant PTX-2 is being tested as an anti-fibrotic agent.	26119353
Inflammation, Primary angiitis of the central nervous system	Altered Intercellular Communication	PACNS is an uncommon condition causing inflammation and destruction of the blood vessels of the central nervous system.	26119979
Inflammation, Helicobacter pylori	Altered Intercellular Communication	Furthermore, the sensitivity, specificity, and positive and negative predictive values of type 3, 4, or 5 morphologies for predicting Helicobacter pylori positive were 94.28%, 96.66%, 98.50%, and 87.87%, respectively, correlated well with inflammation grading according to the Sydney classification (P < 0.01).	26120585
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Our study suggests that gastric mucosal morphologic patterns in the Helicobacter pylori infected gastric mucosa can be reliably identified using C-NBI gastroscopy with good correlation with inflammation grading.	26120585
Inflammation, Choroiditis	Altered Intercellular Communication	Macular serpiginouschoroiditis is a rare variant of serpiginous choroiditis characterized by a severe recurrent inflammation of both central choroid and retinal pigment epithelium.	26120655
Parkinson Disease, Inflammation, Chronic Fatigue Syndrome, palladium	Altered Intercellular Communication	To study clinical characteristics of fatigue syndrome in patients with Parkinson's disease (PD) and a role of inflammation in its development.	26120984
Inflammation, Pregnancy Complications, Infectious, Liver Cirrhosis	Altered Intercellular Communication	We here investigated if low vitamin D levels might be associated with prognosis, inflammation and infectious complications in patients with cirrhosis.	26121590
Airway structure, Inflammation, Bronchial Obstruction, Bronchiectasis	Altered Intercellular Communication	The triplet of airway infection, inflammation and bronchial wall destruction associated with excessive matrix metalloproteinases (MMP) release and imbalance of tissue inhibitor metalloproteinase-1 (TIMP-1) is implicated in bronchiectasis.	26122009
Inflammation, Bronchiectasis	Altered Intercellular Communication	For bronchiectasis patients, baseline measurements consisted of sputum inflammation and MMP measurements, bacterial culture, spirometry and chest high-resolution computed tomography (HRCT).	26122009
Carcinoma, Ovarian Epithelial, Ascites	Altered Intercellular Communication	Inflammation-regulating factors in ascites as predictive biomarkers of drug resistance and progression-free survival in serous epithelial ovarian cancers.	26122176
Inflammation, Chronic Obstructive Airway Disease, Carcinoma of lung, Primary malignant neoplasm	Altered Intercellular Communication	Expansion of myeloid-derived suppressor cells in chronic obstructive pulmonary disease and lung cancer: potential link between inflammation and cancer.	26122358
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) is characterised by deficits in cholinergic neurotransmission and subsequent receptor changes.	26122542
Inflammation	Altered Intercellular Communication	Moderate correlation was found between MRI activity index and eAIS, mural enhancement degree and eAIS; and poor correlation was found between mesenteric inflammation score and eAIS, MRI activity index and AIS, however they were not statistically significant.	26123842
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Portal inflammation during NAFLD is frequent and associated with the early phases of putative hepatic progenitor cell activation.	26124313
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	We investigated whether portal tract inflammation observed in non-alcoholic fatty liver disease (NAFLD) is associated with hepatic progenitor cell compartment activation, as thoroughly evaluated with different markers of the staminal lineage.	26124313
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	NAFLD activity score, fibrosis and portal inflammation were histologically evaluated.	26124313
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Portal inflammation was absent in a minority of patients, mild in 40% of cases and more than mild in about half of patients, showing a strong correlation with fibrosis (r=0.76, p<0.001).	26124313
Inflammation, Portal inflammation	Altered Intercellular Communication	Lobular inflammation, ballooning, myofibroblast activity and hepatic progenitor cell compartment activation were associated with portal inflammation by univariate analysis.	26124313
Portal inflammation	Altered Intercellular Communication	In the multivariate model, the only variable independently associated with portal inflammation was hepatic progenitor cell compartment activation (OR 3.7, 95% CI 1.1 to 12.6).	26124313
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Portal inflammation is frequent during NAFLD and strongly associated with activation of putative hepatic progenitor cells since the first steps of their differentiation, portal myofibroblast activity and fibrosis.	26124313
Airway structure, Chronic Obstructive Airway Disease, Bronchial Hyperreactivity	Altered Intercellular Communication	Bronchial hyperresponsiveness, airway inflammation, and reversibility in patients with chronic obstructive pulmonary disease.	26124655
Airway structure, ARCN1 gene	Altered Intercellular Communication	To evaluate the relationship between BHR, lung function, and airway inflammation in COPD patients.	26124655
chronic inflammatory response	Altered Intercellular Communication	Consequently, the current diagnostic utility of plasma cfDNA quantification has not been thoroughly validated in subjects with chronic respiratory inflammation.	26125447
chronic inflammatory response, Sarcoidosis, Chronic Obstructive Airway Disease, Non-Small Cell Lung Carcinoma, Asthma	Altered Intercellular Communication	We measured plasma cfDNA concentrations in 50 resectable NSCLC patients, 101 patients with chronic respiratory inflammation (chronic obstructive pulmonary disease, sarcoidosis, or asthma) and 40 healthy volunteers using real-time PCR.	26125447
Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	We found significantly higher plasma cfDNA levels in NSCLC patients than in subjects with chronic respiratory inflammation and healthy individuals (P<0.0001).	26125447
chronic inflammatory response	Altered Intercellular Communication	There were no significant differences in plasma cfDNA levels between patients with chronic respiratory inflammation and healthy volunteers.	26125447
Non-Small Cell Lung Carcinoma, Upper Respiratory Infections	Altered Intercellular Communication	The receiver-operating characteristics curve distinguishing NSCLC patients from subjects with chronic respiratory inflammation indicated 56% sensitivity and 91% specificity at the >5.25-ng ml(-1) cutoff (AUC=0.76).	26125447
IGA Glomerulonephritis, Glomerulonephritis, immunoglobulin A, Kidney Diseases	Altered Intercellular Communication	Immunoglobulin A (IgA) nephropathy (IgAN) is a common form of primary glomerulonephritis characterized by diffuse glomerular mesangial IgA1 deposition leading to mesangial proliferation and chronic glomerular inflammation.	26125729
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Knowledge of xanthogranulomatous inflammation is essential to avoid misdiagnosis of malignancy and excessive surgical intervention.	26126317
Gastric Ulcer, CTCAE 5, Carcinoma, Acute and chronic inflammation	Altered Intercellular Communication	H. pylori iceA type 2 was dominant and associated with cagA, chronic active inflammation, gastric ulcer and carcinoma.	26126322
Interstitial inflammation	Altered Intercellular Communication	We selected 480 interstitial inflammation samples for light and electron microscopy and immunohistochemistry of CD138, IgG and IgG4 test.	26126500
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	To describe potential mechanisms by which pepsin induces inflammation in refractive chronic rhinosinusitis (CRS).	26127000
Inflammation, Acute HIV infection	Altered Intercellular Communication	However, in patients who initiated cART during acute HIV infection, mucosal CD4(+) T-cell numbers were fully preserved and markers of microbial translocation and inflammation reversed to normal.	26129649
Inflammation	Altered Intercellular Communication	The aorta in MFS was similar to the aorta in dilated TAV with regard to the presence of medial degeneration and apoptosis, while other markers for degeneration and aging like inflammation and progerin expression were low in MFS, comparable to BAV.	26129868
Colorectal Carcinoma, Gastrointestinal inflammation	Altered Intercellular Communication	The mucosal immune response in the setting of intestinal inflammation contributes to colorectal cancer.	26130064
Inflammation, COL4A2 wt Allele	Altered Intercellular Communication	Inquiry into monocyte-mediated pathways of inflammation and apoptosis may elucidate the basis for the observed association and may be targets for ICH neuroprotection.	26130090
Inflammation, Chronic disease	Altered Intercellular Communication	Dietary components that are known to affect chronic inflammation have been implicated in the etiology and prognosis of these chronic diseases.	26130324
Inflammation, Primary malignant neoplasm, Breast Carcinoma	Altered Intercellular Communication	Inflammation has been linked to cancer but its role in breast cancer is unclear.	26130675
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Iron deficiency is common in patients with inflammatory bowel disease (IBD), but can be difficult to diagnose in the presence of inflammation because ferritin is an acute phase reactant.	26131803
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	IBD activity was assessed on markers of inflammation (C-reactive protein, endoscopy, fecal calprotectin).	26131803
Inflammation, Phlegmon, Fever, CTCAE, Lymphadenitis	Altered Intercellular Communication	Moreover, the finding of fever and lymphadenitis with intense local signs of inflammation and phlegmon is rarely seen as the initial manifestation of Kawasaki disease.	26132362
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	A major component of increased mortality risk in people with chronic kidney disease (CKD) is associated with non-traditional cardiovascular risk factors including markers of inflammation.	26132658
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We studied whether a novel marker of systemic inflammation, elevated serum combined polyclonal immunoglobulin free light chains (cFLC), was an independent risk factor for increased all-cause mortality in people with CKD stage 3.	26132658
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	To conclude, high cFLC levels predict increased mortality in people with stage 3 CKD, independent of established risk factors and other markers of inflammation.	26132658
Airway structure, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	Airway Inflammation in Chronic Rhinosinusitis with Nasal Polyps and Asthma: The United Airways Concept Further Supported.	26132710
Airway structure, Asthma, Bronchitis	Altered Intercellular Communication	We aimed to test two hypotheses: (i) upper and lower airway inflammation in CRSwNP is uniform in agreement with the united airways concept; and (ii) bronchial inflammation exists in all CRSwNP patients irrespective of clinical asthma status.	26132710
Asthma, Bronchitis	Altered Intercellular Communication	Our findings support the united airways concept; however, we did not find evidence for subclinical bronchial inflammation in CRSwNP patients without asthma.	26132710
Airway structure, Nasal Polyps	Altered Intercellular Communication	Finally, this study indicates for the first time that nasal polyps potentially play an important role in the airway inflammation rather than being a secondary phenomenon.	26132710
Inflammation, Fibrosis Assessment, Injury of liver	Altered Intercellular Communication	Histological alterations were shown in 60% of patients, without serious liver injuries (no case of inflammation or significant fibrosis).	26133749
Inflammation, Neoplasms	Altered Intercellular Communication	Chronic inflammation as an important epigenetic and environmental factor for putative tumorigenesis and tumor progression may be associated with specific activation of Toll-like receptors (TLR).	26134824
Pancreatic carcinoma, Neoplasms	Altered Intercellular Communication	Functional analysis in human pancreatic cancer cells point to a significant role of both TLRs in chronic inflammation-mediated TLR7/TLR8 signaling leading to tumor cell proliferation and chemoresistance.	26134824
Inflammation	Altered Intercellular Communication	The ALHE was defined as an EH with a vascular "blow-out" pattern associated with a variable degree of inflammation.	26135557
Inflammation	Altered Intercellular Communication	Studies suggest that inflammation is associated with unfavorable outcome.	26135695
Calcinosis, Atherosclerosis	Altered Intercellular Communication	This signaling cascade is tightly involved in bone formation and mineralization, but may also propagate pathological extraosseous calcification conditions such as calcifying inflammation and atherosclerosis.	26135899
Infectious agent, prostatitis	Altered Intercellular Communication	Exposure to infectious agents has been considered to induce prostatic inflammation and cancerous transformation.	26136219
Brain Abscess, Meningitis	Altered Intercellular Communication	The brain abscess was accompanied by mild meningeal inflammation with negative blood and cerebrospinal fluid cultures.	26137921
Inflammation	Altered Intercellular Communication	In CD, E. coli-laden macrophages expressed high IL-10 & CD163 and lower TNFa, IL-23 & iNOS irrespective of macroscopic inflammation.	26137941
Inflammation	Altered Intercellular Communication	Persistence of E. coli within LP macrophages may provide a stimulus for chronic inflammation.	26137941
Inflammation	Altered Intercellular Communication	Interestingly, SFs from grade 1 and non-OA patient could reduce released NO to 27.10 +- 2.2 mM/ml showing potency to alleviate inflammation.	26138240
Inflammation, Squamous cell carcinoma, Dysplasia, Hyperplasia	Altered Intercellular Communication	The physiologic and pathologic mucosa was described in five obvious vascular patterns observed at Enhanced Contact Endoscopy ranging from normal to squamous cell carcinoma, passing through inflammation, hyperplasia, and dysplasia.	26138390
Inflammation, Dysplasia, Carcinoma, Hyperplasia	Altered Intercellular Communication	Sensitivity, specificity, positive predictive value, and negative predictive value in the differentiation between healthy mucosa and inflammation versus pathologic hyperplasia, dysplasia, and carcinoma were, respectively, 96.6, 93.3, 98.2, 87.5, and 95.9 %.	26138390
Nonalcoholic Steatohepatitis, Hepatitis, Liver Failure, Obesity, Fatty Liver Disease	Altered Intercellular Communication	Non-alcoholic steatohepatitis (NASH) is an obesity associated common cause of liver inflammation and there are concerns that it may turn out to be the most common cause of liver failure as prevalence of obesity increases.	26138508
Inflammation, Postoperative Complications	Altered Intercellular Communication	The mechanisms linking BMI to pediatric postoperative complications are unclear, but cytokine mechanisms or changes in the response to inflammation have been postulated.	26139160
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Low-grade inflammation and endothelial dysfunction scores were computed by averaging Z-scores of six low-grade inflammation markers and four endothelial dysfunction markers respectively.	26139210
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	BclI was not associated with systolic blood pressure, cIMT, low-grade inflammation, endothelial dysfunction, and prevalent CVD.	26139210
Inflammation	Altered Intercellular Communication	Senescent Vascular Smooth Muscle Cells Drive Inflammation Through an Interleukin-1a-Dependent Senescence-Associated Secretory Phenotype.	26139463
Inflammation	Altered Intercellular Communication	Whether senescent VSMCs can actively contribute to atherogenic processes, such as inflammation, is unknown.	26139463
Inflammation, Atherosclerosis	Altered Intercellular Communication	Senescent VSMCs may actively contribute toward the chronic inflammation associated with atherosclerosis through the interleukin-1a-driven senescence-associated secretory phenotype and the priming of adjacent cells to a proatherosclerotic state.	26139463
Inflammation, Atherosclerosis	Altered Intercellular Communication	These data also suggest that inhibition of this potentially important source of chronic inflammation in atherosclerosis requires blockade of interleukin-1a and not interleukin-1b.	26139463
Inflammation, Kit Ligand, human	Altered Intercellular Communication	Previous studies proposed that both inflammation, oxidative stress, and impaired endothelial dysfunction have a significant role in occurrence of slow coronary flow (SCF).	26139836
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	monocyte-to-high density lipoprotein cholesterol ratio (MHR) is a recently emerged indicator of inflammation and oxidative stress, which have been studied only in patients with chronic kidney disease.	26139836
Inflammation, Kit Ligand, human	Altered Intercellular Communication	Higher MHR which indicates an enhanced inflammation and oxidative stress was significantly and independently associated with the presence of SCF.	26139836
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	(18)F-FDG and (18)F-NaF PET/CT demonstrate coupling of inflammation and accelerated bone turnover in rheumatoid arthritis.	26140472
Pituitary Apoplexy, Visual disturbance	Altered Intercellular Communication	Pituitary apoplexy is a rare and potentially life-threatening disorder that is most commonly characterized by a combination of sudden headache, visual disturbance, and hypothalamic/hormonal dysfunction.	26140487
Inflammation, Tacca leontopetaloides, Metabolic Syndrome X	Altered Intercellular Communication	TIA is often associated with metabolic syndrome (causing chronic inflammation), resulting in a proinflammatory- and procoagulant-environment.	26140921
Inflammation, Anemia	Altered Intercellular Communication	Secondary outcomes included CRBSI rate, catheter patency, and biomarkers of inflammation and anemia.	26141306
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	These results suggest that down-regulation of inflammation in active IBD patients might be based on the increased expression of IL-35 and IL-37.	26141420
Inflammation, Atherosclerosis	Altered Intercellular Communication	Obesity-associated inflammation and atherosclerosis might play roles in this association.	26141694
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is a potential pathogenic factor for atherosclerosis and ICVA.	26142261
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Association of metabolic syndrome with testosterone and inflammation in men.	26142486
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Therefore, our objective was to examine the relationship between metabolic syndrome, testosterone and inflammation.	26142486
Inflammation	Altered Intercellular Communication	Subclinical inflammation might play a role in the pathophysiology of storage symptoms.	26142598
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) is a multifactorial disease of unknown cause characterized by sinonasal inflammation, increased mucus production, and defective mucociliary clearance.	26143180
Inflammation, Craniosynostosis	Altered Intercellular Communication	TH2-mediated pendrin expression is increased in NPs of patients with CRS and might lead to increased inflammation, mucus production, and decreased mucociliary clearance.	26143180
Osteomyelitis, Inflammation	Altered Intercellular Communication	Osteomyelitis is an inflammation of the bone marrow mainly caused by bacteria such as Staphylococcus aureus.	26146361
Granulomatous inflammation, Lymphoma	Altered Intercellular Communication	EBUS-TBNA results were categorized as lymphoma, specific nonlymphoma diagnosis, granulomatous inflammation, or adequate or inadequate lymphocytes with no specific diagnosis.	26146788
Granulomatous inflammation, Lymphoma	Altered Intercellular Communication	Granulomatous inflammation diagnosed on the basis of EBUS-TBNA was associated with a low likelihood of lymphoma being present (likelihood ratio, 0.00; 95% confidence interval [CI], 0.00-0.276).	26146788
Inflammation, Neoplasms	Altered Intercellular Communication	The NLRP3 inflammasome complex, an important regulatory factor of inflammation and cell apoptosis, has attracted considerable attention in the development of tumor.	26146985
Inflammation, Pathology	Altered Intercellular Communication	Thus, rapamycin might ameliorate age-related pathologies, including late-life cancer, by suppressing senescence-associated inflammation.	26147250
Heart Diseases, Inflammation, "Dents disease	Altered Intercellular Communication	IFG was an intermediary condition for heart disease, inflammation, and oxidative stress in elderly adults but not for 2-year incident disease or all-cause mortality.	26147402
Inflammation, Calcinosis	Altered Intercellular Communication	Active calcification and inflammation of the carotid atheroma were assessed and compared in symptomatic and asymptomatic plaques by 18F-NaF and 18F-FDG PET/CT.	26147617
Inflammation, Calcinosis	Altered Intercellular Communication	Active calcification and inflammation are simultaneous processes in the symptomatic and asymptomatic carotid atheroma.	26147617
Inflammation, Calcinosis	Altered Intercellular Communication	However, active calcification seems predominant over inflammation in both groups.	26147617
Inflammatory disorder, Gout	Altered Intercellular Communication	Gout is a common inflammation disease resulting from an increase in serum uric acid.	26147675
Inflammation, Breast Carcinoma, Necrosis	Altered Intercellular Communication	Inflammation and cell necrosis are one of the consequences that accompany breast cancer.	26148597
Inflammation, Necrosis	Altered Intercellular Communication	However, inflammation and cell necrosis are well known to be involved in stimulation of cellular and humeral immunity.	26148597
Inflammation, Glomerulonephritis, Vasculitis, CTCAE	Altered Intercellular Communication	ANCA vasculitis encompasses several autoimmune conditions characterised by destruction of small vessels, inflammation of the respiratory tract and glomerulonephritis.	26149790
ARCN1 gene, Inflammation	Altered Intercellular Communication	Non-anaemic iron deficiency is common in COPD and appears to be driven by inflammation.	26150144
Arthralgia, Inflammation	Altered Intercellular Communication	The remaining 88.4% of ultrasound examinations performed in 2011 were intended to investigate inflammation in 25.8%, differential diagnosis of arthralgia in 17.1%, enthesis in 12.6% and temporal arteries in 17.3%, and to conduct ultrasound-guided procedures in 10.6% and study microcrystalline pathologies in 4.7%.	26150268
Inflammation, Pleural effusion disorder, Anemia, Hypoalbuminemia	Altered Intercellular Communication	Larger bilateral pleural effusions in patients with ABAD were associated with hypoalbuminaemia and potentially with anaemia and inflammation, and may increase the length of intensive care unit stay.	26150676
Chronic Obstructive Airway Disease	Altered Intercellular Communication	Effect on Proline-Glycine-Proline and Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease.	26151090
ARCN1 gene, Inflammation	Altered Intercellular Communication	The self-propagating acetyl-proline-glycine-proline (AcPGP) pathway is a novel means of neutrophilic inflammation that is pathologic in the development of COPD.	26151090
Pneumonitis	Altered Intercellular Communication	Roflumilast reduces pulmonary inflammation through decreasing prolyl endopeptidase activity and AcPGP.	26151090
Communicable Diseases, Unknown (origin) (qualifier value)	Altered Intercellular Communication	It can be secondary to an inflammatory condition or infectious disease, however many cases of onychodystrophy are idiopathic in nature.	26151794
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	The inflammation of asthma typically is different than that of COPD, and the degree of inflammation and cellular damage varies with asthma severity.	26152317
Edematous skin, Lichen Sclerosus et Atrophicus, Waldenstrom Macroglobulinemia	Altered Intercellular Communication	The classic histopathologic features of lichen sclerosus et atrophicus (LS) include lymphoplasmacytic inflammation below a zone of dermal edema and sclerosis.	26152335
Inflammation	Altered Intercellular Communication	Trace elements are essential for the functioning of different processes in the body, including the immune system and associated responses to infection/inflammation.	26152852
Inflammation, Thoracic aortic dissection	Altered Intercellular Communication	Because inflammation may be part of the pathogenesis of thoracic aortic dissection, we investigated whether trace element changes associated with inflammation occur in serum and tissue samples during the disease.	26152852
Inflammation	Altered Intercellular Communication	The Cu/Zn ratio in the serum, a marker of infection/inflammation, did not change in the patients.	26152852
Inflammation, Thoracic aortic dissection	Altered Intercellular Communication	Concerning trace element changes in the serum and tissue, our data do not support the hypothesis that inflammation is involved in the pathogenesis of thoracic aortic dissection.	26152852
Sepsis, Inflammation	Altered Intercellular Communication	Expression of CD11c and EMR2 on neutrophils: potential diagnostic biomarkers for sepsis and systemic inflammation.	26153037
Inflammation, Carcinoma of lung, Hamartoma	Altered Intercellular Communication	The (18)F-alfatide RGD PET/CT analysis correctly recognized 17 patients with lung cancer, 4 patients (hamartoma) as true negative, and 5 patients (4 chronic inflammation and 1 inflammatory pseudotumour) as false positive.	26153145
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Association of subclinical inflammation with deterioration of glycaemia before the diagnosis of type 2 diabetes: the KORA S4/F4 study.	26155746
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	The role of biomarkers of subclinical inflammation in the early deterioration of glycaemia before type 2 diabetes is largely unknown.	26155746
Inflammation	Altered Intercellular Communication	T-wave axis deviation is associated with biomarkers of low-grade inflammation.	26155907
Inflammation	Altered Intercellular Communication	These results suggest that a low-grade inflammation likely contributes to the pathogenesis of T- wave axis deviation.	26155907
Inflammation, Ischemic stroke	Altered Intercellular Communication	Evidence is emerging that inflammation plays a key role in the pathophysiology of ischemic stroke (IS).	26156202
Communicable Diseases, Inflammation	Altered Intercellular Communication	TIB pattern reflects endobronchiolar inflammation due mainly but not exclusively to an infectious cause.	26156310
Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation-associated declines in cerebral vasoreactivity and cognition in type 2 diabetes.	26156513
Inflammation, Executive Function	Altered Intercellular Communication	Inflammation may further impair cerebral vasoregulation, which consequently accelerates decline in executive function and daily activities performance in older people with T2DM.	26156513
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	We identified markers of inflammation in VAT, which supports prior evidence regarding the role of visceral adiposity and cancer.	26156741
Inflammation, ELN gene	Altered Intercellular Communication	As ELN correlates with the degree of tissue inflammation, we investigated whether ELN was associated with specific cytokine profiles.	26156866
Organ Dysfunction Scores, Obesity, Fatty infiltration	Altered Intercellular Communication	Obesity is a chronic inflammatory condition and is strongly linked to raised levels of pro-inflammatory factors and may lead to fatty infiltration of multiple internal organs including the gallbladder and liver, causing organ dysfunction.	26158139
Inflammation	Altered Intercellular Communication	For each eye, the grader documented the presence or absence of follicular trachoma (TF) and intense trachomatous inflammation (TI) according to the WHO simplified grading system.	26158573
Follicle, Inflammation, Tissue Factor	Altered Intercellular Communication	A 2-stage cluster-random sampling design selected 30 households from each of 30 clusters per evaluation unit; all residents aged 1 year and older in selected households were examined for evidence of follicular trachoma (TF), intense trachomatous inflammation (TI), and trachomatous trichiasis (TT).	26158575
Airway structure	Altered Intercellular Communication	Interleukin-33 promotes inflammatory cytokine production in chronic airway inflammation.	26158865
Airway structure, ARCN1 gene	Altered Intercellular Communication	Its role in chronic airway inflammation that develops into COPD is widely unknown.	26158865
Airway structure, ARCN1 gene	Altered Intercellular Communication	Thus, the IL-33 is a promoter of chronic airway inflammation that contributes to COPD development.	26158865
Inflammation, Data types - Address	Altered Intercellular Communication	Monocytes are involved in inflammation in AD and are recruited to the diseased brain.	26159193
Inflammation, Eosinophilic esophagitis, Inflammatory disorder, Esophageal Diseases, "Extra-osseous Ewings sarcoma	Altered Intercellular Communication	Eosinophilic esophagitis (EoE) is an inflammatory immune-mediated disease with predominant eosinophilic inflammation characterized by the presence of esophageal dysfunction symptoms.	26159479
vascular inflammations	Altered Intercellular Communication	The detection of vascular inflammation had an important impact, and led to a change of treatment in a high percentage of patients with LVV.	26159505
Inflammation	Altered Intercellular Communication	Although his laboratory data were indicative of severe inflammation, an abdominal examination and a computed tomography (CT) scan did not produce any significant findings.	26160462
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Iron Status and Inflammation in Early Stages of Chronic Kidney Disease.	26160488
Inflammation, Anemia	Altered Intercellular Communication	Novel biomarkers of iron metabolism might be useful to distinguish iron deficiency anemia connected with inflammation and absolute iron deficiency.	26160488
Inflammation, Blood Vessel, Chronic Kidney Diseases	Altered Intercellular Communication	Molecular pathway analysis confirmed the modification of known processes involved in CKD complications, including decreased haemostasis and increased inflammation, complement activation and vascular damage.	26160894
Sepsis, Inflammation	Altered Intercellular Communication	Measurement of circulating levels of the histone H3 provides additional information to that of the conventional indicators of inflammation for determining the severity of sepsis.	26161427
Inflammation, Fracture	Altered Intercellular Communication	Chronic inflammation may increase the risk of fracture, and omega-3 polyunsaturated fatty acids (PUFAs) may reduce fracture risk via down-regulation of inflammatory cytokine gene expression and other mechanisms.	26161450
Inflammation, Fracture	Altered Intercellular Communication	The odds ratio of hip fracture comparing the highest to lowest quartiles was 2.24 (95% confidence interval, 1.05-4.79; P for linear trend, .048) for TNFa-sR1 and 2.83 (95% confidence interval, 1.34-5.99; P for linear trend, .011) for TNFa-sR2, adjusted for FRAX hip fracture score, nutritional variables, and selected factors impacting inflammation; there was a gradient of risk by increasing quartile in TNFa-sR1.	26161450
Inflammation, Helicobacter pylori, Duodenal Diseases	Altered Intercellular Communication	The goal of this study was to analyze the role of Toll-like receptor 4 polymorphisms +896 (rs4986790) and +1196 (rs4986791) in the pathogenesis of Helicobacter pylori related gastroduodenal diseases in relation to gastric secretion and inflammation.	26161647
Gastritis	Altered Intercellular Communication	Toll-like receptor 4 genotypes did not show any association with Helicobacter pylori positivity or the features of gastric inflammation.	26161647
Communicable Diseases, Inflammation	Altered Intercellular Communication	In the aftermath of an ocular bee sting, close surveillance for inflammation and infection is essential.	26161915
prostatitis	Altered Intercellular Communication	PHI was the only determinant for prostatitis vs. BPH, whereas no biomarkers could differentiate prostate inflammation from HG-PIN.	26162485
vascular inflammations, Inflammatory disorder, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is considered to be a systemic vascular inflammatory disease, and oxidative stress is known to be a contributor to vascular inflammation.	26162942
vascular inflammations	Altered Intercellular Communication	Vascular inflammation and oxidative stress are associated with the presence of ELC.	26162942
Inflammation, Intervertebral Disc Degeneration, Pain Distress Question	Altered Intercellular Communication	Our current study strongly demonstrates the potential of TSA for the treatment of inflammation and followed pain in degenerative disc disease.	26163178
Inflammation	Altered Intercellular Communication	In several studies, exposure to fine particulate matter (PM) has been associated with inflammation, with inconsistent results.	26163546
Necrotizing granulomatous inflammation, Mycobacterium Infections, Tuberculosis	Altered Intercellular Communication	Our aim was to determine the clinical usefulness of PCR for differential diagnosis of tuberculosis and nontuberculous mycobacterial infection in lung tissue that show chronic granulomatous inflammation.	26163897
Aortic Diseases, Aortic Aneurysm, Lupus Erythematosus	Altered Intercellular Communication	In patients with a history of systemic lupus erythematosus, with or without active inflammation, screening for aortic disease should be selectively performed if other risk factors for aortic aneurysm are present.	26164362
Inflammation, Chronic Obstructive Airway Disease, hepcidin, Exacerbation	Altered Intercellular Communication	Systemic inflammation up-regulates serum hepcidin in exacerbations and stabile chronic obstructive pulmonary disease.	26164540
Inflammation, Hypoxia	Altered Intercellular Communication	Hepcidin is the main regulator of systemic iron homeostasis and its expression is modulated by iron status, hypoxia, erythroid factors and inflammation.	26164540
ARCN1 gene, Inflammation, Hypoxia, Exacerbation, hepcidin	Altered Intercellular Communication	The aim of our study was to examine a relationship between level of hepcidin and iron status, erythropoietic activity, hypoxia and inflammation in exacerbations and stable COPD patients.	26164540
ARCN1 gene, Inflammation, Hypoxia, hepcidin	Altered Intercellular Communication	We hypothesized that hepcidin concentration is changed in COPD patients and is substantially influenced by inflammation and/or hypoxia.	26164540
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	Systemic inflammation and elevated values of IL-6 present in exacerbations and stabile COPD might be responsible for the observed increased hepcidin level.	26164540
Coronary Arteriosclerosis	Altered Intercellular Communication	Immunoglobulin G4 (IgG4)-related immuno-inflammation has been suggested to affect the development of coronary artery atherosclerosis.	26164687
Dental Plaque	Altered Intercellular Communication	Serum IgG4 concentrations were significantly associated with NCP, especially with LDP, suggesting that IgG4-related immuno-inflammation may play a role in coronary plaque vulnerability.	26164687
Inflammation, Cellulitis, Erythema, Swelling, Skin Infection, CTCAE	Altered Intercellular Communication	In the very next day, initial signs of skin infection appeared including local inflammation, erythema, swelling and cellulitis restricted to saphenectomy site.	26165059
Prostate, Atrophic, Acute and chronic inflammation	Altered Intercellular Communication	Patients with atrophy were older and had a larger prostate, and more acute and chronic prostate inflammation.	26165588
Gingivitis, Dental Plaque, Periodontal Route of Administration	Altered Intercellular Communication	No periodontal destruction, signs of gingival inflammation or increased plaque accumulation was observed.	26165864
ARCN1 gene, Chronic Obstructive Airway Disease, Bronchiolitis	Altered Intercellular Communication	Inflammation of the small airways (bronchiolitis) contributes to airflow limitation by narrowing and obliterating the airway lumen in patients with chronic obstructive pulmonary disease (COPD).	26165891
vascular inflammations	Altered Intercellular Communication	CD4+CD25+FOXP3+ regulatory T cells (Tregs) play a role in the modulation of vascular inflammation.	26166019
Pancreatic Diseases, Pancreatitis	Altered Intercellular Communication	Acute pancreatitis (AP) is the most common pancreatic disease and consists of an acute inflammation of the pancreas.	26166112
Kidney Failure, Chronic, Inflammation, Endothelial dysfunction, Cerebral Atherosclerosis	Altered Intercellular Communication	Inflammation, which initiates endothelial dysfunction, vascular atherosclerosis, and oxidative stress, may negatively influence renal function and accelerate the development of end-stage renal disease (ESRD).	26166123
Inflammation, Congenital Abnormality, Communicable Diseases, Head Injuries, Penetrating, Facial paralysis, Infiltration	Altered Intercellular Communication	Bilateral facial nerve palsy may result from cranial trauma, congenital abnormalities, inflammation, infiltration, or infection, but is rarely associated with syphilis.	26166431
Refractory anemias, Cartilage destruction, Autoimmune Diseases, Rheumatoid Arthritis, Abnormal inflammatory response	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by abnormal inflammation, angiogenesis, and cartilage destruction.	26166764
Inflammation, Carcinoma of lung	Altered Intercellular Communication	It is also suggested that TB predicts raised lung cancer risk likely related to chronic inflammation in the lungs.	26166791
Inflammation, Neoplasms	Altered Intercellular Communication	In two patients, routine inspection was unable to discern whether the lesions were inflammation or tumors.	26167082
Inflammation, Impaired cognition, diabetic, Bipolar Disorder	Altered Intercellular Communication	Serum Soluble Adhesion Molecules and Markers of Systemic Inflammation in Elderly Diabetic Patients with Mild Cognitive Impairment and Depressive Symptoms.	26167502
Inflammation, millicurie, Depressed mood, diabetic	Altered Intercellular Communication	We first demonstrated that elderly diabetic patients with MCI, particularly those with depressive mood have higher levels of soluble adhesion molecules and markers of low-grade systemic inflammation.	26167502
Peripheral Neuropathy, Inflammation, Chemical injury	Altered Intercellular Communication	Non-systemic vasculitic peripheral neuropathy is a rare condition characterized by necrotizing inflammation resulting in luminal narrowing of the vasa nervorum, leading to ischemic injury to peripheral nerves.	26167722
Inflammation, Pain Distress Question	Altered Intercellular Communication	Elevated markers of inflammation in the absence of a possible explanation should prompt the clinician to perform a nerve biopsy; however, it is an invasive procedure and is associated with complications of post-neuropathic pain and delayed wound healing.	26167722
Inflammation, Intestinal Mucosa	Altered Intercellular Communication	We showed a correlation between secreted IFN-g/IL-18 levels, and caspase-1 activation, with inflammation intensity of intestinal CD mucosa explants.	26168332
Multiple Myeloma, Inflammation	Altered Intercellular Communication	Interrelationship between angiogenesis, inflammation and oxidative stress in Indian patients with multiple myeloma.	26169214
Inflammation, Infectious Lung Disorder, Bronchiectasis, Chronic disease	Altered Intercellular Communication	Bronchiectasis is a chronic disorder characterised by permanent and irreversible abnormal dilation of the bronchi and bronchioles, primarily caused by repeated cycles of pulmonary infections and inflammation, which lead to reduced mucociliary clearance and to the excessive production of sputum.	26169808
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Prostaglandins are a group of lipid compounds involved in inflammation and cancer.	26170067
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation is a well-defined factor in Alzheimer's disease (AD).	26170148
Benign prostatic hypertrophy	Altered Intercellular Communication	Benign prostatic hyperplasia is one of the chronic inflammatory conditions in ageing male populations.	26172054
Inflammation, Hypersensitivity, Abnormal digestive tract function, Intestinal infectious disease (disorder)	Altered Intercellular Communication	Etiological factors include gastrointestinal peristalsis disturbances, visceral hypersensitivity, chronic inflammation of the mucous membrane, dysbacteremia, intestinal infections, psychosomatic and nutritional factors.	26172165
Sepsis, Inflammation	Altered Intercellular Communication	His general shape was severe, abdomen was tender at palpation in hypogastrium, peritoneal signs were positive, and blood tests showed highly elevated markers of inflammation, including procalcitonin, what suggested the sepsis.	26172168
Tumor necrosis, Inflammation, Vasogenic Edema, Necrosis	Altered Intercellular Communication	Coexpression of Sur1 and Trpm4 in necrotic endothelial cells was also associated with vasogenic edema indicated by upregulated perivascular tumor necrosis factor, extravasation of serum immunoglobulin G, and associated inflammation.	26172285
Inflammation	Altered Intercellular Communication	There was also no evidence of reduced indicators of inflammation or oxidative stress.	26172395
Asbestos-Related Lung Disorder, Pneumonitis	Altered Intercellular Communication	Further studies should determine the conditions required to increase levels of total anti-oxidant capacity in the blood and in the lungs of subjects with either asbestos-related diseases or subclinical lung inflammation.	26172395
Migraine Disorders	Altered Intercellular Communication	During development, hormonal changes may act on predetermined brain circuits, increasing the probability of migraine.	26172552
Crohn Disease, Inflammation	Altered Intercellular Communication	Clinical remission was defined as Crohn's Disease Activity Index (CDAI) < 150 and endoscopic remission as CDAI < 150 + absence of mucosal lesions + no signs of active inflammation on ileocolonoscopy.	26173493
Inflammation, alpha 1-Antitrypsin Deficiency	Altered Intercellular Communication	Alpha-1 antitrypsin (AAT) encoded by SERPINA1 is an acute-phase inflammation marker, and AAT deficiency (AATD) is known as one of the common genetic disorders in European populations.	26174136
Airway structure	Altered Intercellular Communication	Fraction of exhaled nitric oxide (FeNO) is a marker of eosinophilic airway inflammation.	26174797
Inflammation, Unspecified visual loss	Altered Intercellular Communication	In all three cases, the cause of inflammation was not clear from clinical examination alone and prompt treatment was required to prevent permanent vision loss.	26174811
Inflammation, Ischemic stroke	Altered Intercellular Communication	Immune responses and inflammation play an important role in the pathogenesis of ischemic stroke.	26175305
Inflammation, Thrombosis	Altered Intercellular Communication	The thrombosis probably resulted from inflammation in the adjacent diverticulum.	26176578
Inflammation, Sarcopenia, Obesity	Altered Intercellular Communication	Research suggests that inflammation has an important role in the pathogenesis of obesity and sarcopenia.	26177029
Inflammation, VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)	Altered Intercellular Communication	Association of Angiotensin-Converting Enzyme (ACE) Gene Polymorphism with Inflammation and Cellular Cytotoxicity in Vitiligo Patients.	26177100
Inflammation	Altered Intercellular Communication	Angiotensin converting enzyme (ACE) plays an important role in the physiology of the vasculature, blood pressure and inflammation.	26177100
Neurodegenerative Disorders, Inflammation, Parkinson Disease, "Alzheimers Disease", Neurotoxicity Syndromes, Acute kidney injury, Mental disorders	Altered Intercellular Communication	Brain inflammation results after both acute injury and also with the appearance of mutated proteins or endogenous neurotoxic metabolites associated with slow neurodegenerative diseases such as Alzheimer's and Parkinson's diseases and some psychiatric disorders.	26177578
Inflammation	Altered Intercellular Communication	Microglia play a key role in brain inflammation by the release of pro-inflammatory cytokines and with ageing, microglia exhibit 'priming' leading to increased basal release of the pro-inflammatory cytokines.	26177578
Inflammation, Infection	Altered Intercellular Communication	Preliminary Outcomes of Distal IMAP and SEAP Flaps for the Treatment of Unstable Keloids Subject to Recurrent Inflammation and Infections in the Lower Sternal and Upper Abdominal Areas.	26177690
Inflammation, Neoplasms, Necrosis, Vascular Invasion Assessment, Ulceration, CTCAE	Altered Intercellular Communication	During the pathological process histologic subtype, Breslow thickness and Clark level, tumor cell type, mitotic rate, peritumoral inflammation, as well as ulceration, regression, necrosis, vascular invasion and presence of satellite were analyzed and related to clinical data.	26177701
Airway structure	Altered Intercellular Communication	There were also no significant changes in bacterial load measured by 16S qPCR or in airway inflammation.	26179246
Parkinson Disease, Aggregation, palladium, Colitis	Altered Intercellular Communication	We showed that Parkinson's disease (PD) patients have alpha-synuclein (a-Syn) aggregation in their colon with evidence of colonic inflammation.	26179554
palladium, Dysbiosis	Altered Intercellular Communication	This report provides evidence that proinflammatory dysbiosis is present in PD patients and could trigger inflammation-induced misfolding of a-Syn and development of PD pathology.	26179554
parathyroid hormone secretion, Hyperparathyroidism, Primary	Altered Intercellular Communication	Primary hyperparathyroidism is an endocrinopathic condition characterized by hypersecretion of parathyroid hormone.	26179753
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Amyloid precursor protein metabolism and inflammation markers in preclinical Alzheimer disease.	26180139
Inflammation, Data types - Address, Nerve Degeneration	Altered Intercellular Communication	Our findings suggest that inflammation in the CNS increases in normal aging and is intimately related to markers of neurodegeneration in the preclinical stages of AD and SNAP.	26180139
Inflammation, Overweight	Altered Intercellular Communication	a-Galacto-oligosaccharides Dose-Dependently Reduce Appetite and Decrease Inflammation in Overweight Adults.	26180243
Inflammation, Overweight	Altered Intercellular Communication	Consumption of a-GOSs for 14 d dose-dependently reduced appetite, food intake, and inflammation in overweight adults with no impact of a-GOS composition.	26180243
Inflammation, Spinal Cord Injuries	Altered Intercellular Communication	Cross-sectional associations of pulmonary function with systemic inflammation and oxidative stress in individuals with chronic spinal cord injury.	26180939
Inflammation	Altered Intercellular Communication	Systemic inflammation, and to a lesser extent oxidative stress, have been associated with reduced pulmonary function.	26180939
Inflammation, Spinal Cord Injuries, Stanford Cancer Institute	Altered Intercellular Communication	Our objective was to evaluate the associations between biomarkers of inflammation (C-reactive protein (CRP), interleukin-6 (IL-6)) and novel makers of global oxidative stress (fluorescent oxidation products (FLOx)) with spirometric and lung volume measures in individuals with chronic spinal cord injury (SCI).	26180939
Inflammation	Altered Intercellular Communication	Increased systemic inflammation was associated with reductions in FEV1 and FVC independent of a number of covariates.	26180939
Inflammation, Pulmonary function tests, Stanford Cancer Institute	Altered Intercellular Communication	Although the mechanism is uncertain, these results suggest that reductions in pulmonary function in SCI are associated with systemic inflammation.	26180939
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Persons living with HIV are at increased risk for cardiovascular disease in part because of persistent inflammation and coagulation activation.	26181818
Inflammation, Malnutrition, Anemia	Altered Intercellular Communication	A cohort of 212 hemodialysis patients free of overt inflammation or malnutrition, were treated for anemia with parenteral iron-sucrose and an erythropoesis-stimulating agent, in keeping with current clinical guidelines.	26182077
Inflammation, Hemolysis (biological function)	Altered Intercellular Communication	However, days of storage duration poorly correlated (R(2) <0.10) with all measured indicators of hemolysis and inflammation.	26183122
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Weekly body mass index (BMI), histopathological examination and quantitative real-time PCR analysis on genes involved in lipid metabolism, inflammation and fibrosis were performed.	26183212
Inflammation, precancerous lesions, Pancreatitis, Chronic	Altered Intercellular Communication	As chronic inflammation has been recently demonstrated to promote dissemination of in situ precancerous lesions, we investigated the prognostic significance of PanINs associated with chronic pancreatitis (CP) in PDAC patients.	26183380
Inflammation	Altered Intercellular Communication	PanIN-3 in association with CP is a significant prognostic factor for decreased survival in PDAC patients, suggesting that chronic inflammation may accelerate the progression of preinvasive high-grade PanIN.	26183380
Granuloma	Altered Intercellular Communication	Previous reports have mentioned that pyogenic granulomas in the oral cavity were associated with the female hormonal receptor, vascular endothelial growth factor, and proliferative immune markers; however, no significant staining was observed in our patient.	26184018
Inflammation, Hepatitis	Altered Intercellular Communication	A liver biopsy demonstrated heavy portal tract inflammation, associated interface hepatitis, and numerous necroinflammatory foci throughout the liver parenchyma.	26184021
Inflammation, Acromion, Bursitis	Altered Intercellular Communication	Subacromial bursitis is caused by inflammation of the bursa that separates the superior surface of the supraspinatus tendon from the overlying coraco-acromial ligament and acromion.	26184525
Prostate carcinoma, Neoplasms, prostatitis	Altered Intercellular Communication	Chronic baseline prostate inflammation is associated with lower tumor volume in men with prostate cancer on repeat biopsy: Results from the REDUCE study.	26184556
Prostate carcinoma, prostatitis	Altered Intercellular Communication	To evaluate whether baseline acute and chronic prostate inflammation among men with initial negative biopsy for prostate cancer (PC) is associated with PC volume at the 2-year repeat prostate biopsy in a clinical trial with systematic biopsies.	26184556
Inflammation, Neoplasms	Altered Intercellular Communication	Acute and chronic inflammation and tumor volume were determined by central pathology.	26184556
Inflammation	Altered Intercellular Communication	Acute and chronic inflammation were significantly associated with each other (P < 0.001).	26184556
Inflammation	Altered Intercellular Communication	Chronic inflammation was associated with larger prostate (P < 0.001) and lower pre-repeat biopsy PSA (P = 0.01).	26184556
Inflammation, Neoplasms	Altered Intercellular Communication	At 2-year biopsy, baseline chronic inflammation was associated with lower mean tumor volume (2.07 ul vs. 3.15 ul; P = 0.001), number of biopsy cores involved (1.78 vs. 2.19; P < 0.001), percent of cores involved (17.8% vs. 22.8%; P < 0.001), core involvement (0.21 ul vs. 0.31 ul; P < 0.001), and overall percent tumor involvement (1.40% vs. 2.01%; P < 0.001).	26184556
Inflammation, Neoplasms	Altered Intercellular Communication	Baseline acute inflammation was not associated with any tumor volume measurement.	26184556
Inflammation	Altered Intercellular Communication	In a cohort of men with 2-year repeat prostate biopsy positive for PC after a negative baseline biopsy, baseline chronic inflammation was associated with lower PC volume.	26184556
Inflammation, Postmenopausal state, Breast Carcinoma, Obesity	Altered Intercellular Communication	Adipokines and inflammation may provide a mechanistic link between obesity and postmenopausal breast cancer, yet epidemiologic data on their associations with breast cancer risk are limited.	26185195
Granuloma, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is defined as a chronic inflammatory condition causing continuous mucosal inflammation of the colon without granulomas on biopsy.	26185880
Granuloma, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is defined as a chronic inflammatory condition causing continuous mucosal inflammation of the colon without granulomas on biopsy.	26185880
Inflammation, Neoplasms	Altered Intercellular Communication	This chronic inflammation may lead to a modest increase in neoplasia risk.	26185881
Heart Diseases, Depressive disorder, Chronic heart failure, Depression, CTCAE	Altered Intercellular Communication	Inflammation Markers and Major Depressive Disorder in Patients With Chronic Heart Failure: Results From the Sertraline Against Depression and Heart Disease in Chronic Heart Failure Study.	26186432
Inflammation, Depressive disorder, Congestive heart failure, Minimal Disseminated Disease, Chronic heart failure	Altered Intercellular Communication	Major depressive disorder (MDD) and chronic heart failure (CHF) have in common heightening states of inflammation, manifested by elevated inflammation markers such as C-reactive protein.	26186432
Minimal Disseminated Disease, Inflammation, Depression, CTCAE, Congestive heart failure	Altered Intercellular Communication	MDD in patients with CHF was associated with altered inflammation marker levels compared with patients with CHF who had no depression.	26186432
Inflammation, polychondritis	Altered Intercellular Communication	Relapsing polychondritis is a rare disease characterized by cartilage inflammation.	26187053
Inflammation	Altered Intercellular Communication	Younger African-Americans initially had the highest GFR but showed a steep age-related decrement that was associated with elevated inflammation.	26187318
Perihilar Cholangiocarcinoma	Altered Intercellular Communication	Evaluation of inflammation-based prognostic scores in patients undergoing hepatobiliary resection for perihilar cholangiocarcinoma.	26187429
Primary malignant neoplasm	Altered Intercellular Communication	Inflammation-based prognostic scores have prognostic value in several kinds of cancer.	26187429
Perihilar Cholangiocarcinoma	Altered Intercellular Communication	We evaluated whether inflammation-based prognostic scores are associated with survival of patients with perihilar cholangiocarcinoma.	26187429
Perihilar Cholangiocarcinoma	Altered Intercellular Communication	Inflammation-based scores (i.e., the modified Glasgow Prognostic Score (mGPS), neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, and prognostic nutritional index) were retrospectively evaluated in 534 patients who underwent resection for perihilar cholangiocarcinoma.	26187429
Inflammation, Fracture, Osteopenia	Altered Intercellular Communication	Low grade inflammation is associated with lower velocity of sound and broadband ultrasound attenuation in older men, but not with bone loss or fracture risk in a longitudinal aging study.	26188108
Bone Density, Inflammation, Fracture	Altered Intercellular Communication	Our objective was to investigate whether low grade systemic inflammation was associated with bone markers, bone quality, bone mass and fracture risk in a population of older persons.	26188108
Inflammation, Vitality	Altered Intercellular Communication	Transcriptomic and epigenetic analyses reveal a gender difference in aging-associated inflammation: the Vitality 90+ study.	26188803
Malignant neoplasm of esophagus, Inflammation	Altered Intercellular Communication	Diet-related inflammation and oesophageal cancer by histological type: a nationwide case-control study in Sweden.	26189130
Malignant neoplasm of esophagus, Inflammation	Altered Intercellular Communication	This project sought to test the role of diet-related inflammation in modulating the risk of oesophageal cancer.	26189130
Malignant neoplasm of esophagus, Inflammation	Altered Intercellular Communication	Diet-related inflammation appears to be associated with an increased risk of oesophageal cancer, regardless of histological type.	26189130
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Local inflammation plays a role in the pathophysiology of osteoarthritis (OA) and chemokines exert catabolic effects on articular cartilage either through paracrine and/or autocrine mechanisms.	26189947
Inflammation, Lupus Nephritis	Altered Intercellular Communication	Glomerular deposition of immune complexes and inflammation induce podocyte injury in lupus nephritis (LN).	26191151
Primary malignant neoplasm	Altered Intercellular Communication	There is increasing evidence that the presence of an inflammation-based prognostic score (modified Glasgow prognostic score, mGPS) could predict survival in patients with advanced cancer.	26191228
Autoimmune necrotizing myopathy, Inflammation, Necrosis	Altered Intercellular Communication	Necrotizing autoimmune myopathy (NAM) is characterized pathologically by necrotic muscle fibers with absent or minimal inflammation.	26192196
Inflammation, Prostate carcinoma, Benign prostatic hypertrophy, Prostatic Intraepithelial Neoplasias, Atrophic	Altered Intercellular Communication	Computer-identified features for each of the noncancerous disease categories (eg, benign prostatic hyperplasia [BPH], prostatic intraepithelial neoplasia [PIN], inflammation, and atrophy) and prostate cancer were extracted.	26192734
Inflammation, Primary malignant neoplasm, Atrophic	Altered Intercellular Communication	The focal appearance of lesions on dynamic contrast-enhanced images may help discriminate atrophy and inflammation from cancer.	26192734
Inflammation, Sarcoidosis	Altered Intercellular Communication	Sarcoidosis is a systemic disease characterized by noncaseating granulomatous inflammation with tremendous clinical heterogeneity and uncertain pathobiology and lacking in clinically useful biomarkers.	26193069
Inflammation, Periodontitis, Tooth structure, Premature tooth loss	Altered Intercellular Communication	Progressing as a chronic inflammation at the level of tooth support tissues, untreated chronic periodontitis may lead to a premature loss of the dental organ.	26193206
Hepatitis A, Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	The percutaneous liver biopsy performed on the patients with chronic viral hepatitis C showed a series of histological alterations, the most frequent being: portal inflammation, periportal necrosis, lobular inflammation, focal necrosis, and hepatic fibrosis (scarring).	26193211
Squamous cell carcinoma, Ulcerative inflammation	Altered Intercellular Communication	The first lesion appeared in 2003, it was excised and the histopathological result showed squamous cell carcinoma with undifferentiated areas and chronic ulcerative inflammation.	26193225
Vulvar Lichen Sclerosus, Ulcerative inflammation	Altered Intercellular Communication	The patient underwent radiation therapy remaining at the end of it a small-ulcerated lesion at the superior vulvar commissure, which was biopsied in 2004 showing chronic ulcerative inflammation with reparatory areas of squamous immature benign metaplasia In April 2014, a dermatological consult described vulvar scleroatrophic lichen confirmed by a biopsy.	26193225
Inflammation, Atherosclerosis	Altered Intercellular Communication	Pretransplant malnutrition, inflammation, and atherosclerosis affect cardiovascular outcomes after kidney transplantation.	26194096
Kidney Failure, Chronic, Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	Malnutrition, inflammation, and atherosclerosis (MIA) syndrome is associated with a high mortality rate in patients with end-stage renal disease.	26194096
Acute inflammation	Altered Intercellular Communication	Energized dissection adds to the cytokine-mediated postoperative inflammation.	26194253
prostatitis	Altered Intercellular Communication	Patients With Prostatic Inflammation Undergoing Transurethral Prostatic Resection Have a Larger Early Improvement of Storage Symptoms.	26194294
Metabolic Syndrome X, ETV3 wt Allele, prostatitis	Altered Intercellular Communication	To evaluate the association between prostate inflammation, metabolic syndrome (MetS), and postoperative lower urinary tract symptoms in patients treated with transurethral resection of the prostate (TURP).	26194294
prostatitis	Altered Intercellular Communication	Patients with prostate inflammation presented a 50% risk reduction of postoperative storage urinary symptoms.	26194294
ETV3 wt Allele, prostatitis	Altered Intercellular Communication	We confirmed the association between MetS and prostate inflammation.Patients with inflammatory infiltrates mostly benefit from TURP, particularly regarding storage symptoms.	26194294
Chronic lymphocytic inflammation, Pontine structure, Clippers	Altered Intercellular Communication	Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS Syndrome) was first described in 2010.	26195048
Atherosclerosis	Altered Intercellular Communication	IRF2BP2 Reduces Macrophage Inflammation and Susceptibility to Atherosclerosis.	26195219
Atherosclerosis	Altered Intercellular Communication	Inflammation impairs macrophage cholesterol clearance from vascular tissues and promotes atherosclerosis.	26195219
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Low-grade inflammation in symptomatic knee osteoarthritis: prognostic value of inflammatory plasma lipids and peripheral blood leukocyte biomarkers.	26195278
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	These findings may reflect low-grade inflammation in OA and may be useful as diagnostic and prognostic biomarkers in clinical development of disease-modifying OA drugs.	26195278
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Platelet to lymphocyte ratio as a novel indicator of inflammation is correlated with the severity of metabolic syndrome: A single center large-scale study.	26196312
Inflammation, Blood coagulation	Altered Intercellular Communication	Increased visceral adiposity activates the important pathways connecting low-grade chronic inflammation, oxidative stress and blood coagulation.	26196312
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	In conclusion, our findings showed that increased PLR was significantly associated with both the presence and severity of MetS which was linked to systemic inflammation based on the correlation between PLR and CRP.	26196312
Inflammation	Altered Intercellular Communication	The result was consistent with erosive mucosa with granulation tissue formation and acute inflammation in favor of EM.	26196523
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	However, a systematic analysis of various colonic subcompartments in the pathogenesis of UC before inflammation remains elusive.	26197452
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Our results thus provide new insights into the development of inflammation and relapse in UC and suggest that the stem cell niche in the colon may influence pathogenesis of the disease.	26197452
Inflammation, Physical disability, Sarcopenia	Altered Intercellular Communication	Sarcopenia has been associated with increased systemic inflammation and risk of physical disability in older adults.	26197717
Inflammation, Fever, Lymphohistiocytosis, Hemophagocytic, Hyperferritinaemia	Altered Intercellular Communication	The diagnosis of HLH should be considered in patients who are systemically ill with unexplained fevers and hyperferritinemia who have evidence of inflammation in the CNS.	26198020
Data types - Address	Altered Intercellular Communication	Neurosteroids have recently shown promise in alleviating cognitive and neuronal sequelae of AD.	26198711
Arteritis	Altered Intercellular Communication	Carotid artery inflammation associated with gemcitabine-based therapy: a special report.	26198835
Inflammation, Vasculitis, CTCAE, Thickened	Altered Intercellular Communication	Vasculitis is an inflammation that can present as acute or chronic in nature, which causes changes in the walls of blood vessels, including thickening, weakening, narrowing and scarring.	26198835
Pain Distress Question, Inflammation	Altered Intercellular Communication	Despite adequate pain control, thoracotomy was still associated with significant central and peripheral inflammation.	26198932
Granuloma, Inflammation	Altered Intercellular Communication	CNGM was characterized by lobulocentric granulomas with mixed inflammation and clear vacuoles lined by neutrophils within granulomas.	26200100
Inflammation, Carcinoma of lung, Tuberculosis, Pulmonary	Altered Intercellular Communication	It may usually be misdiagnosed as inflammation including pulmonary tuberculosis, even lung cancer, because its clinical symptoms and signs are often nonspecific.	26200643
Inflammation	Altered Intercellular Communication	Inflammation was suspected, but malignance cannot be excluded.	26200643
Obesity	Altered Intercellular Communication	Obesity Is a Positive Modulator of IL-6R and IL-6 Expression in the Subcutaneous Adipose Tissue: Significance for Metabolic Inflammation.	26200663
Inflammation	Altered Intercellular Communication	The role of IL-6R/IL-6 axis in metabolic inflammation remains controversial.	26200663
Inflammation, Obesity	Altered Intercellular Communication	It was, therefore, concluded that obesity was a positive modulator of IL-6R and IL-6 expression in the adipose tissue which might be a contributory mechanism to induce metabolic inflammation.	26200663
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Relationship Between Physical Frailty and Low-Grade Inflammation in Late-Life Depression.	26200706
Inflammation, Depression, CTCAE	Altered Intercellular Communication	To determine whether physical frailty is associated with low-grade inflammation in older adults with depression, because late-life depression is associated with physical frailty and low-grade inflammation.	26200706
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Only performance-based physical frailty is associated with low-grade inflammation in late-life depression, which might point to a specific depressive subtype.	26200706
Arterial Stiffness, Inflammation, Prediabetes syndrome, Diabetes Mellitus	Altered Intercellular Communication	Arterial stiffness and endothelial inflammation in prediabetes and newly diagnosed diabetes patients.	26201008
Arterial Stiffness, Inflammation, Prediabetes syndrome, Diabetes Mellitus	Altered Intercellular Communication	We aimed to study e-selectin levels, and their associations with serum markers of inflammation and arterial stiffness in prediabetes and newly diagnosed diabetes patients in this study.	26201008
Inflammation, physiopathological	Altered Intercellular Communication	Serum e-selectin may be a good marker of endothelial inflammation and dysfunction increasing in parallel with serum glucose levels, predicting future cardiovascular events.	26201008
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Excessive	Altered Intercellular Communication	COPD (chronic obstructive pulmonary disease) is associated with sustained inflammation, excessive injury, and accelerated lung aging.	26201096
Inflammation	Altered Intercellular Communication	Moreover, KL depletion increased cell sensitivity to cigarette smoke-induced inflammation and oxidative stress-induced cell damage.	26201096
ARCN1 gene, Inflammation	Altered Intercellular Communication	Reduced KL expression in COPD airway epithelial cells was associated with increased oxidative stress, inflammation and apoptosis.	26201096
Inflammation, Chronic sinusitis, Craniosynostosis, Obesity	Altered Intercellular Communication	Both obesity and chronic rhinosinusitis (CRS) are characterized by inflammation.	26201473
Dermatitis, Atopic, Psoriasis	Altered Intercellular Communication	Expression of Neuropeptides, Neurotrophins, and Neurotransmitters in the Skin of Patients with Atopic Dermatitis and Psoriasis.	26201903
Gingivitis, Dental Plaque	Altered Intercellular Communication	Secondary end points were levels of dental plaque and gingival inflammation.	26202995
Bacteremia, Hypotension, CTCAE, Inflammation, Renal Insufficiency	Altered Intercellular Communication	The main clinical predictors of bacteremia were antibiotic use, hypotension, renal dysfunction and systemic inflammation.	26203565
Blepharitis, Conjunctivitis	Altered Intercellular Communication	Sixteen patients with posterior blepharitis and conjunctival inflammation due to MGD were treated with azithromycin, 1%, drops for 4 weeks.	26204109
Arthralgia, Inflammation, Pericarditis, CTCAE, Raynaud Phenomenon	Altered Intercellular Communication	A 17-year-old adolescent girl was admitted with chronic arthralgia, Raynaud phenomenon, pericarditis, and evidences of chronic diffuse inflammation.	26204208
Inflammation, Kidney Failure	Altered Intercellular Communication	Is there a connection between inflammation, telomerase activity and the transcriptional status of telomerase reverse transcriptase in renal failure?	26204404
Sarcopenia	Altered Intercellular Communication	This process, known as "inflamm-aging," is associated with physical frailty and sarcopenia.	26204934
Inflammation	Altered Intercellular Communication	Increased inflammation but similar physical composition and function in older-aged, HIV-1 infected subjects.	26204934
Inflammation, HIV-1 Infection Pathway, Physical impairment	Altered Intercellular Communication	The purpose of our study was to determine if inflammation during treated HIV-1 infection worsens physical impairment in older individuals.	26204934
Inflammation	Altered Intercellular Communication	Despite careful balancing for age, BMI, medications and co-morbidities, the HIV-infected group still displayed evidence of significant chronic inflammation, including elevated sCD14, CRP, IL-6 and CD57(+) T cells, although the magnitude of this inflammation was unrelated to physical impairment.	26204934
Inflammation, Injury of kidney	Altered Intercellular Communication	No significant difference was observed in the levels of biomarkers for renal injury and systemic inflammation response.	26205311
Acute Coronary Syndrome, Electrocardiogram: myocardial infarction (finding), Inflammation	Altered Intercellular Communication	(Comparison of Biomatrix Versus Gazelle in ST-Elevation Myocardial Infarction [STEMI] [COMFORTABLE]; NCT00962416; and Inflammation and Acute Coronary Syndromes [SPUM-ACS]; NCT01000701).	26205445
Emphysematous cystitis	Altered Intercellular Communication	Emphysematous cystitis is an unusual inflammatory condition characterised by the presence of air within the bladder wall and lumen.	26206783
Acute Kidney Injury, CTCAE, Inflammation, Traumatic injury, Clostridium difficile enteritis	Altered Intercellular Communication	Analysis of severe blunt trauma patients with C. difficile, as compared with non-CDI patients, reveals evidence of increased inflammation, immunosuppression, worse acute kidney injury, higher NISS, greater days in the hospital and on the ventilator, higher organ injury scores, and prolonged clinical courses.	26207402
CX3CL1 wt Allele, Inflammation, Traumatic injury, Communicable Diseases	Altered Intercellular Communication	FKN is multifactorial in origin: androgens, inflammation, trauma, ingrowing hairs and secondary infection have all been implicated in its aetiology.	26207661
Inflammation, Squamous cell carcinoma of esophagus	Altered Intercellular Communication	Diet and inflammation have been suggested to be important risk factors for esophageal squamous cell cancer (ESCC).	26208592
Inflammation, Cardiovascular Diseases, Refractory anemias, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Rheumatoid Arthritis, Haiti, Hypertension, CTCAE	Altered Intercellular Communication	Both nocturnal hypertension (HT) and systemic inflammation underlying rheumatoid arthritis (RA) have been shown to be independent predictors of cardiovascular disease (CVD), although little is known on the relationship between nocturnal blood pressure (BP) and disease activity in RA patients.	26208672
Glaucoma, CTCAE, Acute inflammation	Altered Intercellular Communication	Glaucoma cases were more likely to have postoperative inflammation (OR 1.73, P < .0001), prolonged elevated intraocular pressure (OR 2.96, P = .0003), and additional surgery within 30 days (OR 1.92, P = .03).	26210863
Inflammatory abnormality of the eye	Altered Intercellular Communication	Fourteen patients (56%) presented with ocular surface inflammation.	26210866
Inflammation	Altered Intercellular Communication	Though typically noninflammatory, a variant form characterized by prominent inflammation exists.	26210866
Inflammation	Altered Intercellular Communication	When inflammation was intense, covering ileostomy was performed, and an omental plasty was placed between the bowel anastomosis and bladder.	26211219
Diastolic dysfunction, Inflammation, Renal function, Renal Insufficiency	Altered Intercellular Communication	Our main findings were that (i) HF patients had significantly higher serum DLL1 levels than healthy control subjects, (ii) DLL1 levels were significantly correlated with neurohormonal activation, systemic inflammation, and impaired kidney function, (iii) high DLL1 levels were associated with diastolic dysfunction and reduced exercise capacity, but not with impaired systolic function, and (iv) in univariate analysis, but not after multivariable adjustment, high levels of DDL1 were associated with adverse outcome.	26211721
Inflammation, Fibrosis Assessment, Injury of liver	Altered Intercellular Communication	Chemokines, such as CXCR3-ligands, have been identified to play an important role during hepatic injury, inflammation and fibrosis.	26212075
Lichen Planus	Altered Intercellular Communication	Lichen planus (LP) is an autoimmune inflammatory condition of the skin and mucous membranes, of unknown aetiology, that infrequently involves the eye.	26212185
Synaptic Transmission, Epileptic Syndromes, Syndrome, Intellectual Disability	Altered Intercellular Communication	Syntaxin Binding Protein 1 (STXBP1) mutations determine a central neurotransmission dysfunction through impairment of the synaptic vesicle release, thus causing a spectrum of phenotypes varying from syndromic and non-syndromic epilepsy to intellectual disability of variable degree.	26212315
Refractory anemias, Degenerative polyarthritis	Altered Intercellular Communication	Mixed synoviocytes in RA and OA possessed all major Gas-coupled neurotransmitter receptors.	26212359
Inflammation, Heart failure, Bipolar Disorder	Altered Intercellular Communication	NGAL and other markers of inflammation as competitive or complementary markers for depressive symptom dimensions in heart failure.	26212793
Communicable Diseases	Altered Intercellular Communication	Sixteen T-Ports had been explanted due to 15 stoma reactions (14 inflammations and one infection) and one tilting of the T-Port.	26213103
Inflammation, Aortic Aneurysm	Altered Intercellular Communication	PPAR-g agonist attenuates inflammation in aortic aneurysm patients.	26213347
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	All 3 laboratory indices of fibrosis accurately reflected liver fibrosis in patients with SVR for 5 years despite the normalization of serum liver transaminase activity and the lack of liver inflammation.	26214180
Inflammation, dystrophic, Fibrosis Assessment, Muscle fiber necrosis, Paresis, Cachexia	Altered Intercellular Communication	The disease phenotype is characterized by muscle weakness and wasting, and dystrophic features including muscle fiber necrosis, inflammation and fibrosis.	26214262
Inflammation, Malnutrition, Toxic effect, Malignant Head and Neck Neoplasm, Mental disorders	Altered Intercellular Communication	Effect on long-term survival of psychiatric disorder, inflammation, malnutrition, and radiotherapy-related toxicity in patients with locally advanced head and neck cancer.	26214644
Inflammation, Malnutrition, Toxic effect	Altered Intercellular Communication	Inflammation, malnutrition and RT-related toxicity had no significant impact on OS.	26214644
Communicable Diseases, Inflammation, Hepatitis C	Altered Intercellular Communication	It is generally accepted that inflammation that occurs in response to hepatocyte infection by the hepatitis C virus (HCV) is the main mechanism that triggers myofibroblast differentiation and stimulation in chronic hepatitis C. The aim of this study was to determine if HCV might infect human liver myofibroblasts (HLMF) and directly stimulate their fibrogenic activities.	26214688
Liver carcinoma, Hepatitis, Chronic	Altered Intercellular Communication	Chronic liver inflammation and immune/inflammatory response promote hepatocellular carcinoma.	26215124
Neoplasms	Altered Intercellular Communication	High densities of liver-infiltrating lymphocytes in HCV-HCC cirrhotic parenchyma prevail inflammatory conditions and could contribute to tumorigenesis and tumour recurrence.	26215124
Intraocular inflammation, Infiltration, Vitreous opacities	Altered Intercellular Communication	In these patients, intraocular inflammation and vitreous opacities resolved, and chorioretinal infiltrates evolved into fibrotic scars.	26215152
Inflammation	Altered Intercellular Communication	The intervening stroma showed granulation tissue with severe active chronic inflammation.	26216921
Intestinal metaplasia, Inflammation, Gland	Altered Intercellular Communication	Chronic inflammation, neutrophil activity, glandular atrophy, and intestinal metaplasia scores were significantly lower in Mongolian compared to Japanese H. pylori-positive patients (P < 0.0001), with the exception of the intestinal metaplasia score of specimen from the greater curvature of the upper body.	26217093
Hashimoto Disease, Inflammation, Endothelial dysfunction, Haiti	Altered Intercellular Communication	The etiopathogenesis of Hashimoto's thyroiditis (HT) - has not been clearly elucidated although the role of chronic inflammation, endothelial dysfunction, and imbalance between pro- and anti-inflammatory cytokines has been established.	26218277
Inflammation, Blood Vessel	Altered Intercellular Communication	C-reactive protein (CRP) is a biomarker of inflammation, and high levels of CRP correlate with vascular death.	26218286
Neurodegenerative Disorders, Inflammation, Nerve Degeneration	Altered Intercellular Communication	Chronic inflammation is considered to be involved in neurodegeneration, although there is no evidence linking it with the process of neurodegenerative diseases.	26218286
palladium, Inflammation	Altered Intercellular Communication	The associations were independent from PD duration, PD severity, cognitive function, ages, and nutritional conditions, suggesting the possibility that subclinical chronic inflammation is associated with a neurodegenerative process in PD.	26218286
Inflammation, Clostridium perfringens, Necrosis	Altered Intercellular Communication	The microbiology report of blood culture revealed clostridium perfringens, while her pathology showed necrosis and acute inflammation of fibroadipose tissue, skeletal muscle, and fat.	26218953
Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	Adiposity is an inflammatory condition contributing to the morbidity and mortality of several disorders, including type 2 diabetes mellitus (T2D) and cardiovascular disease.	26219155
Fibrosis Assessment, Calcinosis, Acute and chronic inflammation, Pericarditis, Constrictive	Altered Intercellular Communication	Constrictive pericarditis (CP) is an uncommon disease resulting from chronic pericardial inflammation, fibrosis and calcification.	26219528
Proctitis, Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	More work is needed to determine whether IL-6 is a valid marker of colorectal inflammation and whether such inflammation contributes to colon and rectal cancer risk.	26220152
Inflammation	Altered Intercellular Communication	Prognostic value of (18)F-fluorodeoxyglucose PET-CT imaging in acute aortic syndromes: comparison with serological biomarkers of inflammation.	26220267
Carcinoma of lung	Altered Intercellular Communication	Circulating Inflammation Markers, Risk of Lung Cancer, and Utility for Risk Stratification.	26220734
Inflammation, Carcinoma of lung	Altered Intercellular Communication	The incorporation of an inflammation score combining these four markers did not improve the sensitivity (77.6% vs 75.8%, P = .33) or specificity (56.1% vs 56.1%, P = .98) of risk-based lung cancer models.	26220734
ovarian neoplasm, Carcinogenesis, Inflammation, Carcinoma of lung	Altered Intercellular Communication	Circulating levels of CRP, SAA, sTNFRII, and CXCL9/MIG were reproducibly associated with lung cancer risk in two independent studies within the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial, underscoring an etiologic role for inflammation in lung carcinogenesis, though replication is needed in other populations.	26220734
Inflammation, Pneumoconiosis	Altered Intercellular Communication	The interleukin 17A (IL-17A) which is located on chromosome 6p and has been linked to chronic inflammation, is an important candidate gene conferring coal workers' pneumoconiosis (CWP).	26223249
Inflammation, Malnutrition, Communicable Diseases, malignant disease, Liver damage, Traumatic injury	Altered Intercellular Communication	Its serum level is reduced in many clinical conditions, such as liver damage, inflammation, injury, infection, malnutrition, and malignant disease.	26223693
Inflammation, Colonization	Altered Intercellular Communication	We hypothesized bacterial colonization promotes inflammation and that might be associated with renal outcome.	26223871
Inflammation	Altered Intercellular Communication	Also these diseases are associated with chronic inflammation.	26224042
Inflammation, Acromegaly	Altered Intercellular Communication	Our study results suggest that subclinical inflammation may play a role in increased incidence of mortality and morbidity, which depends on uncontrolled IGF-1 levels in patients with acromegaly.	26224042
Inflammation, Obesity	Altered Intercellular Communication	Low-grade chronic inflammation is a salient feature of obesity and many associated disorders.	26224080
Inflammation, Obesity	Altered Intercellular Communication	Understanding how obesity is related to inflammation may allow the development of therapeutics aimed at improving metabolic parameters in obese patients.	26224080
Inflammation	Altered Intercellular Communication	These novel findings suggest that the deregulated hyper-responsiveness to hypoxic stimulus of ASC from visceral AT of obese subjects may contribute via paracrine mechanisms to low-grade chronic inflammation, which has been implicated in obesity-related morbidity.	26224080
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Low-grade chronic inflammation plays a pathogenic role in cardiovascular disease.	26224329
Infectious Lung Disorder, Pneumonitis	Altered Intercellular Communication	Exhaled nitric oxide (eNO) and carbon monoxide (eCO) are markers of pulmonary inflammation associated with acute graft rejection and lung infections in lung transplant (LTX) recipients.	26224473
Airway structure	Altered Intercellular Communication	LTX patients affected by BOS showed higher levels of FeNO 150 and 350, and CalvNO than non-BOS LTX patients, probably due to chronic airway inflammation and fibrotic remodelling.	26224473
Inflammation, Dental Plaque	Altered Intercellular Communication	These findings suggest that the limited capacity of MSCs to differentiate into macrophages could possibly result in decreased macrophage density within the arterial plaque, reduced inflammation, and subsequently enhance plaque stability.	26224580
palladium, Inflammation, Malnutrition, diabetic	Altered Intercellular Communication	Baseline 25(OH)D level was 16.15 (12.13 - 21.16) nmol/L, which was closely associated with diabetic status, longer PD duration, malnutrition, and inflammation.	26224791
Chronic myeloproliferative disorder	Altered Intercellular Communication	Evaluation of Inflammation Parameters in Philadelphia Negative Chronic Myeloproliferative Neoplasia Patients.	26225646
Inflammation, Chronic myeloproliferative disorder	Altered Intercellular Communication	Recent studies have suggested that chronic inflammation can be a triggering factor in the clonal change in chronic myeloproliferative neoplasia (CMPN).	26225646
Inflammation	Altered Intercellular Communication	Nepalese patients infected with strains belonging to hpEurope showed higher inflammation in the antrum than strains from the Nepalese specific population (P = 0.05).	26226153
ARCN1 gene, Airway structure	Altered Intercellular Communication	COPD is characterized by chronic airway inflammation and remodeling, with serious modifications of the extracellular matrix (ECM).	26226411
Airway structure	Altered Intercellular Communication	AECOPDs are associated with increased HYAL activity in BAL and subsequent degradation of HA, which may contribute to airway inflammation and subsequent lung function decline during exacerbations.	26226411
Orbital Pseudotumor	Altered Intercellular Communication	Periprosthetic Tissue Loss in Patients With Idiopathic Vitreous Inflammation After the Boston Keratoprosthesis.	26226472
Inflammation	Altered Intercellular Communication	Blood-cell bioenergetics are associated with physical function and inflammation in overweight/obese older adults.	26226578
Exanthema, Fever, CTCAE, Interstitial inflammation, Dysplasia of anus, Nephritis, Interstitial, Tubulitis Assessment, Acute Kidney Injury, CTCAE	Altered Intercellular Communication	Acute interstitial nephritis (AIN) presents with acute kidney injury, with evidence of interstitial inflammation and tubulitis on histology, and the presence of fever, rash, and eosinophiluria.	26226951
Inflammation	Altered Intercellular Communication	Plasma TNF-a Is Associated with Inflammation and Nutrition Status in Community-Dwelling Japanese Elderly.	26226964
Malnutrition, Disability, Inflammation, Obesity	Altered Intercellular Communication	Inflammation has been suggested to play an important role in age-related chronic diseases and disability, and it is associated with nutritional status including obesity and malnutrition.	26226964
Inflammation, Malnutrition	Altered Intercellular Communication	The results of this study suggest that plasma TNF-a is associated with inflammation and insulin resistance in both Japanese elderly men and women, and a prominent association of TNF-a with malnutrition status was observed in elderly women.	26226964
physiopathological	Altered Intercellular Communication	These results suggest that PCDH1 is important for airway function as a physical barrier, and its dysfunction is involved in the pathogenesis of allergic airway inflammation.	26227965
Intraocular inflammation	Altered Intercellular Communication	Visual acuity improved in 12 eyes (86 %) and intraocular inflammation decreased in 13 eyes (93 %) from 1 week to 3 months after the first injection.	26228441
Malignant - descriptor, Inflammation	Altered Intercellular Communication	In patients with complete or near eradication of malignant T cells, residual clinical inflammation was associated with cytokine production by benign T cells.	26228486
Inflammation, Carcinoma of lung	Altered Intercellular Communication	From January 2010 to May 2012, we retrospectively studied 459 metastatic lymph nodes in 298 lung cancer patients and 176 reactive lymph nodes in 90 patients with nonspecific inflammation.	26228606
Inflammation, Obesity	Altered Intercellular Communication	Educational level and chronic inflammation in the elderly--the role of obesity: results from the population-based CARLA study.	26230620
Inflammation, Obesity	Altered Intercellular Communication	General obesity mediates roughly one-third of the association of education with chronic inflammation in the elderly.	26230620
Inflammation, Impaired cognition, Hyponatremia	Altered Intercellular Communication	Fifty patients (10.5%) had hyponatremia; these patients tended to be older and less educated, to have less inflammation, and to have the higher prevalence of cognitive impairment.	26231192
Inflammation, Interstitial inflammation	Altered Intercellular Communication	The rA2-19F strain in neonatal mice caused substantial lung pathology including interstitial inflammation and airway mucus production, while A2 caused minimal inflammation and mucus production.	26231396
Pneumonitis	Altered Intercellular Communication	Pulmonary inflammation was characterized by enhanced Th2 and reduced Th1 and effector CD8(+) T cells compared to A2.	26231396
Presenile dementia, Inflammation, Atherosclerosis	Altered Intercellular Communication	Age-related diseases, such as atherosclerosis and dementia, are associated with oxidative stress and chronic inflammation.	26231485
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	Pleiotropic effect of the proton pump inhibitor esomeprazole leading to suppression of lung inflammation and fibrosis.	26231702
Pulmonary Emphysema, Pneumonitis	Altered Intercellular Communication	Bilirubin treatment suppresses pulmonary inflammation in a rat model of smoke-induced emphysema.	26232645
Airway structure, Pulmonary Emphysema	Altered Intercellular Communication	Cigarette smoking is a significant risk factor for emphysema, which is characterized by airway inflammation and oxidative damage.	26232645
Arthritis, Joints	Altered Intercellular Communication	In RA joints, FDG uptake was seen mostly by inflammatory cells; therefore, FDG uptake reflected joint inflammation.	26232929
Alzheimers Disease", Impaired cognition	Altered Intercellular Communication	Disruption of cholinergic neurotransmission exacerbates Ab-related cognitive impairment in preclinical Alzheimer's disease.	26233262
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Disruption in cholinergic neurotransmission is one of the earliest neuropathological changes in preclinical Alzheimer's disease (AD) and may be associated with abnormal beta-amyloid (Ab) accumulation.	26233262
Cognition Disorders, Data types - Address	Altered Intercellular Communication	Therefore, disruption of cholinergic neurotransmission with scopolamine may unmask otherwise undetectable cognitive deficits in preclinical AD.	26233262
Inflammation, Behcet Syndrome	Altered Intercellular Communication	Lower CYP2C9 activity in Turkish patients with Behcet's disease compared to healthy subjects: a down-regulation due to inflammation?	26233334
Sepsis, Inflammation	Altered Intercellular Communication	These findings tend to support previous reports that indicated that Gas6 behaves as an acute phase reactant and can be considered a general marker of inflammation rather than a specific biomarker of sepsis.	26233610
Inflammation, Chronic disease, Nerve Degeneration	Altered Intercellular Communication	Multiple sclerosis (MS) is a chronic disease of the central nervous system characterized by inflammation and accompanied and followed by neurodegeneration.	26233805
Nephritis, Interstitial, Inflammation, Kidney Diseases, Renal glomerular disease	Altered Intercellular Communication	Postoperatively, an elevation of the serum IgG4 level was confirmed at 403 mg/dL; however, there was no evidence of tubulointerstitial nephritis or glomerulopathy, including membranous nephropathy, and the urothelium of the renal pelvis was intact without inflammation.	26234232
Granulomatosis, Granulomatosis with polyangiitis, Systemic Vasculitis	Altered Intercellular Communication	Granulomatosis with polyangiitis (GPA; formerly Wegener's) can present with clinical and histopathological features similar to those of immunoglobulin-G4 related disease (IgG4-RD), a recently described fibro-inflammatory condition.	26234733
Airway structure, Asthma, Smooth muscle (tissue), Airway Obstruction	Altered Intercellular Communication	In asthma condition, the airway inflammation accompanied by bronchial smooth muscle spasm cause airway obstruction.	26234928
Malignant neoplasm of esophagus	Altered Intercellular Communication	Impact of inflammation-based prognostic score on survival after curative thoracoscopic esophagectomy for esophageal cancer.	26235238
Alzheimers Disease	Altered Intercellular Communication	Nilotinib and bosutinib modulate pre-plaque alterations of blood immune markers and neuro-inflammation in Alzheimer's disease models.	26235435
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) brains exhibit plaques and tangles in association with inflammation.	26235435
Data types - Address	Altered Intercellular Communication	The non-receptor tyrosine kinase Abl is linked to neuro-inflammation in AD.	26235435
Inflammation	Altered Intercellular Communication	In addition, interleukin-6 (IL-6), albumin, C-reactive protein, and neutrophil gelatinase-associated lipocalin (NGAL) were measured as markers of inflammation.	26235932
Inflammation, Fibrosis Assessment, Kidney Diseases	Altered Intercellular Communication	In both diseases, the identified peptides were linked to pathways recognized to contribute to nephropathy, including fibrosis, inflammation, angiogenesis, and mineral metabolism.	26237555
Idiopathic hypertrophic pachymeningitis	Altered Intercellular Communication	Idiopathic hypertrophic pachymeningitis is a rare inflammatory condition with diffuse thickening of the dura mater, which may cause a compressive effect or vascular compromise.	26238133
Communicable Diseases, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	NLR gene polymorphisms may shift the balance between pro- and anti-inflammatory cytokines and modulate the risk of infection, chronic inflammation, and cancer.	26238283
Inflammation, Obesity, Cerebrovascular accident	Altered Intercellular Communication	Epigenetic mechanisms could be involved in obesity, inflammation and stroke.	26238466
Inflammation, Urinary tract infection, Pain Distress Question	Altered Intercellular Communication	The same enzymes contributing to the synthesis of leukotrienes LTB4 and LTC4, mediators of inflammation and pain, were found in the UTI and ASB cohorts.	26238715
Inflammation, Lung diseases, Bacterial Infections	Altered Intercellular Communication	Chronic inflammation of the airways is a central component in lung diseases and is frequently associated with bacterial infections.	26239109
Pneumonitis	Altered Intercellular Communication	In vivo imaging indicated that VR1 strain, releasing in its culture supernatant metalloproteases and other virulence factors, induced lung inflammation while the VR2 strain presented with a severely reduced pro-inflammatory activity.	26239109
Pain Distress Question, Inflammation	Altered Intercellular Communication	Two-thirds of the patients reported either no pain or only mild intensity pain and moderate inflammation, two days after surgery.	26241450
Inflammation, Hyperemia	Altered Intercellular Communication	The postoperative conjunctival hyperemia, eye irritation signs and inflammation reactions were mild.	26241526
Inflammation, Tumor Cell Invasion	Altered Intercellular Communication	It allows the evaluation of periosteal invasion and therefore bone invasion to be reliably distinguished from inflammation or compression.	26241670
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Elevated inflammatory parameters and inflammation scores are associated with poor prognosis in patients undergoing pulmonary metastasectomy for colorectal cancer.	26242317
Carcinoma, Transitional Cell	Altered Intercellular Communication	The Prognostic Significance of Inflammation-Associated Blood Cell Markers in Patients with Upper Tract Urothelial Carcinoma.	26242371
Electrocardiogram: myocardial infarction (finding), allergic inflammation	Altered Intercellular Communication	Allergic Inflammation Is Associated With Coronary Instability and a Worse Clinical Outcome After Acute Myocardial Infarction.	26243785
Acute Coronary Syndrome, allergic inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	The role of allergic inflammation in acute coronary syndromes (ACS) has not been clearly defined to date.	26243785
Inflammation, Immune dysregulation, Rosacea	Altered Intercellular Communication	Although its etiology is not well defined, rosacea is associated with immune dysregulation and inflammation potentiated by external factors.	26244354
Retinal Edema, Retinitis, Inflammatory abnormality of the eye	Altered Intercellular Communication	The interaction of photoreceptors with the aging RPE, as well as possible low-grade ocular inflammation causing diffuse inner retinal edema, may be the key to the progressive vision changes in HIV-positive patients without overt retinitis.	26244973
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Intestinal fibrosis is a process driven by chronic inflammation leading to increased presence of myofibroblasts and collagen deposition.	26245217
Inflammation	Altered Intercellular Communication	Severity of inflammation was scored according to the Geboes score on haematoxylin and eosin stainings.	26245217
Inflammation	Altered Intercellular Communication	Colectomy specimens from patients with acute UC showed significantly more inflammation than those with longstanding disease [19 vs 9 points, p = 0.01].	26245217
Inflammation, Edema, Nodularity	Altered Intercellular Communication	She underwent flexible sigmoidoscopy, which demonstrated "patchy inflammation and an isolated area of severe deep ulceration with nodularity and oedema".	26245287
Nephritis	Altered Intercellular Communication	Deletion of angiotensin-converting enzyme 2 exacerbates renal inflammation and injury in apolipoprotein E-deficient mice through modulation of the nephrin and TNF-alpha-TNFRSF1A signaling.	26245758
Abnormal renal function, Nephritis, Injury of kidney	Altered Intercellular Communication	More importantly, rhACE2 treatment significantly reversed Ang II-induced renal inflammation, superoxide generation, kidney dysfunction and adverse renal injury in ApoEKO mice with suppression of the NOX4 and TNF-alpha-TNFRSF1A signaling.	26245758
Nephritis, Injury of kidney	Altered Intercellular Communication	ACE2 deficiency exacerbates kidney inflammation, oxidative stress and adverse renal injury in the ApoE-mutant mice through modulation of the nephrin, NOX4 and TNF-alpha-TNFRSF1A signaling.	26245758
Renal Insufficiency, Inflammation, Kidney Glomerulus	Altered Intercellular Communication	While rhACE2 supplementation alleviates inflammation, renal dysfunction and glomerulus injury in the ApoE-mutant mice associated with upregulations of Ang-(1-7) levels and nephrin expression and suppression of the TNF-alpha-TNFRSF1A signaling.	26245758
Tumor necrosis, Progranulins, Inflammation	Altered Intercellular Communication	Progranulin is a growth factor that is active in wound repair and is an antagonist of tumor necrosis factor (TNF) receptors, regulating fibroblast activation, angiogenesis, and inflammation.	26245842
Inflammation, Pathology	Altered Intercellular Communication	Taken together, our results underscore the importance of NEIL2 in protecting mammals from the development of various pathologies that are linked to genomic instability and/or inflammation.	26245904
Kidney Failure, Chronic, Inflammation, Atherosclerosis, Diabetes Mellitus, Hypertension, CTCAE	Altered Intercellular Communication	Aside from traditional factors (e.g., diabetes, age, and hypertension), some hematological parameters, such as neutrophil-to-lymphocyte ratio (NLR), red blood cell distribution width (RDW), and mean platelet volume (MPV), have increasingly been reported as measures of systemic inflammation and atherosclerosis in patients with end-stage renal disease (ESRD).	26246038
Communicable Diseases, Inflammation	Altered Intercellular Communication	Recent research has revealed that although elderly subjects have increased baseline inflammation as compared with their younger counterparts, the elderly do not respond to severe infection or injury with an exaggerated inflammatory response.	26246141
Refractory anemias, Rheumatoid Arthritis, Inflammation, atherosclerotic	Altered Intercellular Communication	Results of a recent study suggested that the excess cardiovascular (CV) risk observed in patients with rheumatoid arthritis (RA) could be partially explained by the presence of immune complexes of antibodies against citrullinated proteins that locally promote and perpetuate inflammation and progression of atherosclerotic plaques.	26246227
Inflammation, Obesity	Altered Intercellular Communication	A secondary aim is to determine whether these relationships are mediated by a reduction in underlying subclinical inflammation associated with obesity.	26246241
Inflammation, Atrophy of cerebellum	Altered Intercellular Communication	Cerebrospinal fluid showed continuous inflammation and magnetic resonance imaging (MRI) revealed cerebellar atrophy and hot cross-bun sign.	26248690
Fibrosis Assessment, Pneumonitis	Altered Intercellular Communication	Our findings suggest that increased Gal-9 levels in the lung have a protective role against lung inflammation and fibrosis in patients with COP through the induction of Tregs in the lung and CD44-dependent inhibitory effects on lung fibroblast cells.	26249221
Hereditary Diseases, Inflammation, Disease	Altered Intercellular Communication	The clinical diseasome is a network representation of the relationships between diseases, in which diseases are connected if they co-occur more than expected at random; in the molecular diseasome, diseases are linked if they share associated genes or interaction between proteins.The results showed that about half of the disease pairs identified in the clinical diseasome had a biological counterpart in the molecular diseasome, particularly those related to inflammation and vascular tone regulation.	26250499
Acute inflammation	Altered Intercellular Communication	The agreement between unenhanced MRE vs. CE-MRE in interpreting active bowel inflammation was 96% (123/128 bowel segments; one-sided 95% confidence interval [CI], >94.4%).	26250897
Inflammation, Traumatic injury	Altered Intercellular Communication	Periodontal inflammation is characterized by injuries in collagen, epithelial, bone tissues.	26251029
Inflammation	Altered Intercellular Communication	Acute 98.2%, and chronic 89.28% inflammation was a significant positive for myeloperoxidase.	26251029
Inflammation	Altered Intercellular Communication	The results indicate that the pathogenesis of periodontal inflammation might involve inhibition of cell death, through the overexpression of bcl-2, due to identifying factors myeloperoxidase (result in the DNA damage by the product of catalysis).	26251029
Inflammation	Altered Intercellular Communication	The highest levels of s100 activity have been found at sites with chronic inflammation.	26251029
Inflammation, Liver carcinoma, Neoplasms, FAM126A gene	Altered Intercellular Communication	While the roles of HMGB1 in inflammation and cell differentiation have been previously reported, its role in tumor cell migration and invasion, particularly in hepatocellular carcinoma (HCC), has remained elusive.	26252226
Chronic lymphocytic inflammation, Pontine structure, Clippers, Inflammatory disorder	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disorder of the central nervous system; it has only recently been defined and to date has received only limited attention.	26252983
Granulomatous inflammation	Altered Intercellular Communication	He will remain under our care to ensure that any further complications such as granulomatous inflammation are managed and documented.	26252991
Inflammation	Altered Intercellular Communication	For now we can only speculate as to the long-term consequences, but these may include carcinogenic change or granulomatous inflammation.	26252991
Inflammation, Dyslipidemias, Cerebrovascular accident	Altered Intercellular Communication	Apoptotic markers and DNA damage are related to late phase of stroke: Involvement of dyslipidemia and inflammation.	26253215
Inflammation, Brain Injuries, Acute Cerebrovascular Accidents	Altered Intercellular Communication	Oxidative stress and brain inflammation are thought to contribute to the pathophysiology of cerebral injury in acute stroke, leading to apoptosis and cell death.	26253215
Inflammation, Acute Cerebrovascular Accidents	Altered Intercellular Communication	Lipid accumulation may lead to progression of carotid plaques and inflammation, contributing to increased acute stroke risk.	26253215
Dermatitis, Atopic, Data types - Address, Immune-mediated	Altered Intercellular Communication	Atopic dermatitis (AD) is characterized by epidermal barrier failure and immune-mediated inflammation.	26253344
Inflammation, Eating	Altered Intercellular Communication	EAT is suggested to promote CAD by paracrine mechanisms and local inflammation.	26253562
Inflammation, Damage, Cerebrovascular accident	Altered Intercellular Communication	IL-10 expression limits inflammation and restricts the size of CNS damage from stroke.	26253723
Inflammation	Altered Intercellular Communication	Angiopoietin-like protein-2 (ANGPTL2) mediates chronic inflammation.	26254352
Primary malignant neoplasm	Altered Intercellular Communication	The Glasgow Prognostic Score (GPS), an inflammation-based prognostic score, has been shown to predict the clinical outcomes of a variety of cancer types.	26254380
Unresectable Colorectal Carcinoma, Neoplasms	Altered Intercellular Communication	Significance of Markers of Systemic Inflammation for Predicting Survival and Chemotherapeutic Outcomes and Monitoring Tumor Progression in Patients with Unresectable Metastatic Colorectal Cancer.	26254405
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Markers of systemic inflammation, such as the neutrophil to lymphocyte ratio (NLR), C-reactive protein (CRP) level and Glasgow prognostic score (GPS), have been reported to be useful prognostic indicators for various types of cancers.	26254405
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	However, most of the existing reports investigated the preoperative status, and the significance of markers of systemic inflammation remains unclear in patients with unresectable metastatic colorectal cancer.	26254405
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Pre-treatment markers of systemic inflammation are useful for predicting prognosis in patients with unresectable metastatic colorectal cancer who receive palliative chemotherapy.	26254405
Diabetic Nephropathy, Inflammation	Altered Intercellular Communication	Recent research has implicated that the inflammation may be a key pathophysiological mechanism in diabetic nephropathy (DN).	26255081
Inflammation, Dengue Fever	Altered Intercellular Communication	These results suggest that inflammation and endothelial activation are important pathways in the pathogenesis of dengue and sICAM-1 levels may identify individuals at risk of plasma leakage.	26255888
maltoheptaose binding, Inflammation	Altered Intercellular Communication	S-maltoheptaose targets syndecan-bound effectors to reduce smoking-related neutrophilic inflammation.	26256047
Airway structure	Altered Intercellular Communication	The antagonistic actions of SM against syndecan-1 binding of NE and CINC-1 in smoke-exposed airways suggest new therapeutic opportunities for modulating airway inflammation in smokers with SM delivery.	26256047
Senile Plaques, Inflammation	Altered Intercellular Communication	The inclusion criteria were: penile plaque volume <1 cm(3); clinical characteristics and ultrasonographic appearance compatible with active inflammation; and penile curvature <45deg.	26257044
Inflammation	Altered Intercellular Communication	Several protein plasma levels and protein isotypes related to inflammation and thrombo-coagulating phenomena were independently associated with the risk of future CVD death.	26258425
Inflammation	Altered Intercellular Communication	Microbial translocation and chronic inflammation may contribute to non-AIDS morbidity in patients with HIV.	26258571
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Probiotic intervention seemed to reduce markers of coagulation and inflammation without overt changes in microbial translocation.	26258571
Inflammation, Lymphoplasmacytic Infiltrate	Altered Intercellular Communication	Definite histopathological findings and immunohistochemistry revealed profound chronic inflammation, showing lymphoplasmacytic IgG-positive infiltration of a resected part of a common bile duct, highly suggestive for the diagnosis of IAC.	26259410
Inflammation, Malignant Pleural Mesothelioma, 1-methyl-1-piperidinomethane sulfonate	Altered Intercellular Communication	Chronic inflammation plays a key role in the pathogenesis of malignant pleural mesothelioma (MPM) as a result of asbestos exposure.	26259877
Airway structure, Carcinoma of lung	Altered Intercellular Communication	Lung cancer may be associated with airway acidification due to enhanced airway inflammation and oxidative stress.	26260979
Nephritis	Altered Intercellular Communication	And investigations into mechanisms underlying renal inflammation may provide new insight into novel therapeutic targets for patients with DN.	26261550
Inflammation, Squamous cell carcinoma	Altered Intercellular Communication	Granulomatous inflammation of pulmonary squamous cell carcinoma: a rare phenomenon.	26261667
Inflammation, Neoplasms	Altered Intercellular Communication	In other instances, granulomatous inflammation is observed in the lymph nodes draining a tumor.	26261667
Granulomatous inflammation, Squamous cell carcinoma	Altered Intercellular Communication	Herein, we report of a 75-year-old man with pulmonary squamous cell carcinoma (SCC), where granulomatous inflammation was observed extensively at the primary site.	26261667
Airway structure, neutrophilic, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic Obstructive Pulmonary Disease exacerbations are associated with worsening of airway inflammation, the nature of which may be neutrophilic, eosinophilic, or both.	26263037
Airway structure, Exacerbation	Altered Intercellular Communication	The primary objective was to examine the cellular nature of airway inflammation in successive COPD exacerbations in order to ascertain if they changed in individual patients.	26263037
Inflammation	Altered Intercellular Communication	These results indicate that folate and Cbl concentrations may influence the levels of oxidative damage, inflammation, and NAD(H), both systemically and within the CNS.	26263423
Inflammation	Altered Intercellular Communication	Sustained concentrations of inflammation in young women, not their response to stress, may contribute to their adverse outcomes post-MI.	26263552
Inflammation	Altered Intercellular Communication	However, environmental factors, such as chronic comorbidities and chronic inflammation, are at least in part responsible for the association between factor VIII and mortality.	26264493
Ischemia, Inflammation, Cardiac dysfunction	Altered Intercellular Communication	Oxidative stress following ischaemia and reperfusion, as well as inflammation, are thought to be important for the development of cardiac dysfunction after cardiac surgery.	26265068
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Chronic inflammation plays a key role in cancer etiology.	26265203
Inflammation	Altered Intercellular Communication	The results suggest that aluminum-induced CRP may in part contribute to a pathophysiological state associated with a chronic systemic inflammation of the human vasculature.	26265215
Inflammation, senile, Data types - Address, "Alzheimers Disease	Altered Intercellular Communication	It is assumed that IL-4 may involve in the inflammation pathology of surrounding senile plaques in Alzheimer's disease (AD) patients.	26265379
Inflammation, Perforation (observation)	Altered Intercellular Communication	Barium esophagram and esophagogastroduodenoscopy revealed no signs of perforation or inflammation.	26266352
Inflammation, Fibrosis Assessment, IgG4-Related Sclerosing Disease	Altered Intercellular Communication	IgG4-related disease (IgG4-RD) is a rare entity consisting of inflammation and fibrosis that has been described in multiple organs.	26266361
Pneumonitis, Alveolar wall	Altered Intercellular Communication	Interestingly, prophylactic BAFFR-Fc administration significantly attenuated pulmonary inflammation and destruction of alveolar walls.	26266827
Alveolar, Pneumonitis	Altered Intercellular Communication	Antagonizing BAFF in CS-exposed mice attenuates pulmonary inflammation and alveolar destruction.	26266827
Inflammation, Prostate Cancer Outcomes Study, Polycystic Ovary Syndrome	Altered Intercellular Communication	Selenium supplementation could be effective on reproductive outcomes, biomarkers of inflammation, and oxidative stress among women with polycystic ovary syndrome (PCOS).	26267328
Inflammation, Metabolic Syndrome X, Atherosclerosis, Cardiovascular Diseases, Sarcopenia, MS gene	Altered Intercellular Communication	evidences have shown a strongly association between metabolic syndrome (MS), cardiovascular diseases and chronic low-grade inflammation, being this last, related with the occurrence of sarcopenia and atherosclerosis.	26268113
SLC25A20 gene, Pulmonary Emphysema, HIV Infections, Chronic inflammatory disorder	Altered Intercellular Communication	In this cross-sectional study of HIV-infected patients, there was an independent association between emphysema and CAC, after adjustment for traditional cardiovascular risk factors, suggesting a common pathogenesis of these chronic inflammatory conditions in a chronic inflammatory disease such as HIV infection.	26268373
physiopathological	Altered Intercellular Communication	Active nasal and paranasal sinus inflammation in GPA leads to olfactory dysfunction, the patients are often unaware of.	26269029
Arteriosclerosis, Interstitial inflammation, Edema, Interstitial Fibrosis Assessment, Tubular atrophy	Altered Intercellular Communication	Scoring was done from 0-3 for interstitial edema, interstitial fibrosis and tubular atrophy (IFTA), interstitial inflammation and arteriosclerosis.	26269223
Malignant tumor of colon, Inflammation	Altered Intercellular Communication	Analysis of local chronic inflammatory cell infiltrate combined with systemic inflammation improves prognostication in stage II colon cancer independent of standard clinicopathologic criteria.	26270488
Inflammation, 2000, Stage II Colon Cancer AJCC v7	Altered Intercellular Communication	In order to evaluate the potential clinical utility of inflammatory markers in Stage II colon cancer, we examined local and systemic inflammation in a consecutive series of patients with resected Stage II colon cancer between 2000 and 2010 who were identified from a prospective clinical database.	26270488
Inflammation, Chronic pain	Altered Intercellular Communication	By using peripheral inflammation in rats as a chronic pain model, the authors identified the deregulation of proteases and their inhibitors as a hallmark of chronic pain development using a genome-wide screening approach.	26270939
Inflammation	Altered Intercellular Communication	Endothelial activation and inflammation have been suggested to play an important role in the pathogenesis of cSVD.	26271106
Esophageal Stricture, Inflammation, Esophagitis	Altered Intercellular Communication	Peptic esophageal strictures due to chronic reflux-associated inflammation were revealed in 0.2% of examined patients (3.7% of patients with erosive esophagitis).	26271421
Inflammation	Altered Intercellular Communication	Sternoclavicular joint resection was performed usually in 2-3 months after subsidence of inflammation.	26271565
Cancer-related fatigue, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation and oxidative stress are involved in the process of chronic renal failure (CRF).	26271951
Cancer-related fatigue, Inflammation, Sleep disturbances	Altered Intercellular Communication	CRF patients show indication of sleep disturbances, and the melatonin rhythm, which modulates sleep, is abnormal in these patients; however, it is still unclear whether inflammation could be related to the blockage of melatonin production and sleep disturbances in this population.	26271951
Inflammation, Ventricular arrhythmia, Cardiomyopathies	Altered Intercellular Communication	Incidence of abnormal positron emission tomography in patients with unexplained cardiomyopathy and ventricular arrhythmias: The potential role of occult inflammation in arrhythmogenesis.	26272522
Ventricular arrhythmia, Myocarditis, Cardiomyopathies	Altered Intercellular Communication	The incidence of myocardial inflammation in patients with unexplained cardiomyopathy referred for ventricular arrhythmias (VAs) is unknown.	26272522
Inflammation, Sarcoidosis	Altered Intercellular Communication	When biopsy was performed, histologic diagnosis revealed nongranulomatous inflammation in 6 patients and sarcoidosis in 18 patients.	26272522
Myocarditis, Cardiomyopathies	Altered Intercellular Communication	Nearly 50% of patients referred with unexplained cardiomyopathy and VA demonstrate ongoing focal myocardial inflammation on FDG PET.	26272522
Inflammation, Chronic Fatigue Syndrome	Altered Intercellular Communication	Comparison of Q fever fatigue syndrome (QFS) and chronic fatigue syndrome (CFS) patients, with a focus on markers of inflammation and fatigue-related cognitive-behavioural variables.	26272528
Inflammation	Altered Intercellular Communication	Japanese adults (n = 245) aged 80 years were classified into quartiles based on periodontal inflamed surface area (PISA), which quantifies the degree of periodontal inflammation.	26272677
Parkinson Disease, Inflammation	Altered Intercellular Communication	Amyloid fibrils are the molecular trigger of inflammation in Parkinson's disease.	26272943
palladium, Inflammation	Altered Intercellular Communication	Although the presence of amyloid deposits of a-synuclein (a-syn) is the main pathological feature, PD brains also present a severe permanent inflammation, which largely contributes to neuropathology.	26272943
Inflammation, Fibrosis Assessment, Calcinosis	Altered Intercellular Communication	Studies suggest that the progression of CAVS is actively regulated with valve endothelial injury leading to inflammation, fibrosis and calcification.	26273067
Inflammation, Damage	Altered Intercellular Communication	Such metabolic damage signals may activate inflammasome and trigger chronic inflammation.	26273672
Diabetic Retinopathy, Acute inflammation	Altered Intercellular Communication	Short Pulse Duration High-Power Laser Photocoagulation during Vitrectomy for Diabetic Retinopathy Reduces Postoperative Inflammation.	26273824
Inflammation, GDC Disease Response Terminology	Altered Intercellular Communication	The significant lower inflammation after short pulse duration PC than conventional PC indicates that the short pulse duration PC protocol should be considered to treat DR.	26273824
vascular inflammations, Abnormally opaque structure (morphologic abnormality)	Altered Intercellular Communication	The imaging and intraoperative observations suggest that the opacities behaved like infiltrates and were associated with vitreous rather than vascular inflammation.	26273931
Refractory anemias, Inflammation	Altered Intercellular Communication	These findings persisted despite adjustment for markers of inflammation (C-reactive protein and interleukin-6 levels) and were seen only in RA, not in controls (adjusted multiplicative interaction P = 0.001-0.077).	26274015
vascular inflammations	Altered Intercellular Communication	There were no statistically significant differences between the effects of K-MBSR, walking, and patient education on stress, glycemic control, or vascular inflammation.	26275164
Vascular System Injuries, Inflammation, Pancreatitis Necrotizing	Altered Intercellular Communication	However, this technique must be performed very cautiously due to the risk of vascular injury which can be difficult to repair in the context of severe local inflammation related to pancreatic necrosis.	26275532
Neuromuscular hamartoma	Altered Intercellular Communication	Neuromuscular and Vascular Hamartoma of the Small Intestine: An Exuberant Reparative Process Secondary to Chronic Inflammation.	26275621
Inflammation	Altered Intercellular Communication	Our findings, together with current observations in the field, provide a rationale to identify adipocyte-lymphocyte cross-talk that instigates adipose inflammation.	26276010
Inflammation, Psoriasis	Altered Intercellular Communication	S100A7 (psoriasin) is overexpressed in psoriasis, suggesting a determinant role of this protein in inflammation and keratinocyte differentiation.	26276441
Inflammation, Cholangiocarcinoma	Altered Intercellular Communication	Association between variants in inflammation and cancer-associated genes and risk and survival of cholangiocarcinoma.	26276523
Inflammation, Carcinogenesis, FBN2 wt Allele	Altered Intercellular Communication	This study shows a lack of association between variants of genes related to inflammation and carcinogenesis and CCA risk and survival.	26276523
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	The correlation between CRP and UA in the patients with ACS indicates the association of oxidative stress and inflammation intensity in damaged cardiomyocytes.	26276649
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Correlation between UA and CRP in apparently healthy individuals indicates a possible role of UA as a marker of low-grade inflammation and its potential in risk assessment in cardiovascular diseases.	26276649
Inflammation, Abnormal degeneration	Altered Intercellular Communication	Joint degeneration is considered to result from the direct effects of blood components on cartilage and indirectly from synovial inflammation.	26276670
Inflammation, Empyema, Tuberculosis	Altered Intercellular Communication	Histopathology revealed 79 (37.6%) cases were tuberculosis, 64 (30.5%) were malignant (primary from lung and other sites), 62 (29.5%) were non-specific inflammation and 5 (2.4%) were empyema.	26277666
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Inflammation is an important hallmark of all cancers.	26277868
Inflammation	Altered Intercellular Communication	Inflammation and increased erythropoiesis stimulating agents (ESA) requirement are frequently associated in patients on dialysis.	26278270
Inflammation	Altered Intercellular Communication	The observed reduction in ESAdose requirement is independent either on convection or diffusion, but is directly associated to the concomitant reduction of inflammation.	26278270
Inflammation, Data types - Address	Altered Intercellular Communication	It is accepted that inflammation contributes to the pathogenesis of AD.	26278415
Granulomatous inflammation, Pneumonia, Interstitial	Altered Intercellular Communication	Significance of granulomatous inflammation in usual interstitial pneumonia.	26278696
Inflammation	Altered Intercellular Communication	Recently mesenchymal stem cells derived from periodontal ligament (PDLSCs) have been utilized to reconstruct tissues destroyed by chronic inflammation.	26278788
Inflammation, Endothelial dysfunction, Cerebrovascular accident	Altered Intercellular Communication	We measured biomarkers of inflammation, endothelial dysfunction and hemostasis for >1 month after stroke and compared biomarker levels between stroke subtypes.	26279056
Inflammation, Thrombosis	Altered Intercellular Communication	These results indicate that, in terms of AMI pathophysiology, the sCD40L cannot be consider just as being involved in thrombosis and inflammation but also as having a relevant role in vascular and endothelial dysfunction.	26279254
Inflammation, Rheumatoid Arthritis, Cardiovascular Diseases	Altered Intercellular Communication	Antibodies to high-density lipoproteins are associated with inflammation and cardiovascular disease in rheumatoid arthritis patients.	26279255
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Several lines of evidence suggest that chronic inflammation and immune dysregulation are related to altered lipid profiles in rheumatoid arthritis (RA), but the actual mechanisms are still unclear.	26279255
Inflammation	Altered Intercellular Communication	We determined that aging and amyloid pathology are associated with inflammation and impaired synaptic function in the hippocampal CA1 region as the result of epigenetic-dependent alterations in gene expression.	26280576
Inflammation	Altered Intercellular Communication	In both amyloid and aging models, inflammation was associated with increased gene expression linked to a subset of transcription factors, while plasticity gene deregulation was differentially mediated.	26280576
Heart Diseases, Inflammation, Bothered by Vomiting, Headache	Altered Intercellular Communication	This is a case of a 10-year-old girl suffering from cyanotic heart disease that was presented with subacute onset of headache, vomiting, and some signs of inflammation.	26280627
Communicable Diseases, Inflammation, Intraventricular, Neoplasms	Altered Intercellular Communication	Neuroradiologists suspected an intraventricular tumor, but cardiac history and signs of inflammation led to lumbar puncture and evidence of CNS infection, and intraventricular abscess was suspected.	26280627
Diabetic Nephropathy, Inflammation	Altered Intercellular Communication	The findings confirm the concept that chronic inflammation is involved in the development of diabetic kidney disease.	26281195
Inflammation, Uveitis	Altered Intercellular Communication	The primary anatomical location of inflammation is either in the anterior segment or pan uveitis.	26281489
Sepsis	Altered Intercellular Communication	Analysis of whether patients with primary, secondary and tertiary sepsis, defined by the presence or absence of recent systemic inflammation-inducing events before the onset of sepsis, differ in clinical presentation, microbiological test results, treatment received and outcome.	26282255
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation plays a crucial role in different stages of cancer development and has long been associated with various types of cancer.	26282902
Malignant neoplasm of urinary bladder, Cystitis	Altered Intercellular Communication	For this study, 3 groups of subjects were considered: patients harboring bladder cancer, subjects affected by bladder inflammation (CTR1), and healthy subjects (CTR0).	26282902
Inflammation, Behavior Disorders, Obesity, Diabetes Mellitus	Altered Intercellular Communication	The promotion of adipose tissue inflammation by lifestyle-related diseases such as obesity and diabetes accelerates atherogenesis; however, the underlying mechanisms remain incompletely understood.	26282945
Inflammation	Altered Intercellular Communication	Nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 (NLRP3) inflammasome contributes to chronic inflammation in adipose tissue.	26282945
Inflammation, Infection, Cardiovascular Diseases, Atherosclerosis	Altered Intercellular Communication	Periodontal infections have been linked to cardiovascular disease, including atherosclerosis, and systemic inflammation has been proposed as a possible mediator.	26282947
Inflammation, Diverticulitis	Altered Intercellular Communication	The groups were equivalent for sex, age, status of diverticulitis, the presence of acute inflammation in the specimen, and the percentage of teaching operations, but the percentage of patients with accompanying diseases was significantly more frequent in groups 2, 3, and 4 (p = 0.04, 0.008, and 0.018, respectively).	26283162
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Microglia are involved in immune surveillance in intact brains and become activated in response to inflammation and neurodegeneration.	26283879
Inflammation	Altered Intercellular Communication	The source of this chronic inflammation is due to the repeated and progressive activation of immune cells.	26284585
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	Our results indicate that age-induced lung inflammation is further elevated after CS exposure in old mice, potentially via an age-induced change in immune cell susceptibility to CS thereby accelerating the pathophysiological hallmarks of COPD.	26284585
prostatitis	Altered Intercellular Communication	Transition Zone Prostate-specific Antigen Density Could Better Guide the Rebiopsy Strategy in Men With Prostate Inflammation at Initial Biopsy.	26284593
prostatitis	Altered Intercellular Communication	To assess the role of transition zone prostate-specific antigen density (TZPSAD) in determining rebiopsy strategy in men with prostate inflammation at initial biopsy.	26284593
Inflammation, Prostate	Altered Intercellular Communication	Eligible patients were divided into 2 groups based on the presence of chronic inflammation in prostate.	26284593
Inflammation	Altered Intercellular Communication	Group 1 consisted of 920 patients with histopathologic evidence of chronic inflammation and group 2 consisted of 1287 patients with no evidence of inflammation.	26284593
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Chronic inflammation at initial biopsy was associated with a significant decrease in the likelihood of cancer detection during rebiopsy (odds ratio, 0.42; 95% confidence interval, 0.18-0.99).	26284593
Inflammation, Prostate	Altered Intercellular Communication	Applying TZPSAD is advantageous in determining rebiopsy strategy in patients with proven inflammation of prostate at initial biopsy.	26284593
Necrotizing granulomatous inflammation, Malignant Neoplasms	Altered Intercellular Communication	Mediastinal Granulomatous Inflammation and Overall Survival in Patients with a History of Malignancy.	26284901
Necrotizing granulomatous inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Investigators have postulated that mediastinal granulomatous inflammation is associated with prolonged overall survival in patients with cancer.	26284901
Necrotizing granulomatous inflammation, Primary malignant neoplasm	Altered Intercellular Communication	We sought to determine whether mediastinal granulomatous inflammation affects overall survival in patients with a history of treated cancer.	26284901
Mediastinal lymphadenopathy, Granuloma, Primary malignant neoplasm, Necrotizing granulomatous inflammation	Altered Intercellular Communication	Patients with a history of treated cancer who underwent endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) for evaluation of mediastinal or hilar lymphadenopathy were grouped based on whether they had mediastinal granulomatous inflammation or benign mediastinal lymphadenopathy without granulomas.	26284901
Necrotizing granulomatous inflammation, Mediastinal lymphadenopathy	Altered Intercellular Communication	We reviewed the records of 106 patients (44 with mediastinal granulomatous inflammation and 62 with benign mediastinal lymphadenopathy).	26284901
Necrotizing granulomatous inflammation, Mediastinal lymphadenopathy	Altered Intercellular Communication	The 3-year survival rate was 90% overall and 93 and 88% in patients with mediastinal granulomatous inflammation and benign mediastinal lymphadenopathy, respectively (P=0.40).	26284901
Necrotizing granulomatous inflammation, Mediastinal lymphadenopathy, Cancer-Related Death	Altered Intercellular Communication	After multivariate adjustment, whether patients had mediastinal granulomatous inflammation or benign mediastinal lymphadenopathy did not significantly affect the risk of cancer death (mediastinal granulomatous inflammation to benign mediastinal lymphadenopathy hazard ratio, 1.27; P=0.76).	26284901
Necrotizing granulomatous inflammation, Primary malignant neoplasm, Mediastinal lymphadenopathy	Altered Intercellular Communication	These results suggest that patients who develop mediastinal granulomatous inflammation after cancer treatment do not have an increased overall survival when compared with patients who develop benign mediastinal lymphadenopathy.	26284901
Airway structure	Altered Intercellular Communication	Systemic response to bacterial colonisation and immune complex deposition secondary to chronic airway inflammation is thought to be underlying mechanism of the disease.	26284926
Inflammation, Sarcopenia	Altered Intercellular Communication	Previous studies have found inflammation, growth factors, and androgen signaling pathways all contribute to sarcopenia.	26286594
Inflammation, Uveitis	Altered Intercellular Communication	The patients had statistically significant fewer episodes of anterior uveitis, shorter duration of episodes and fewer total days of inflammation per year while on topical cyclosporine 0.05%.	26286822
Inflammation, Asthma	Altered Intercellular Communication	TSLP may be used as a biomarker for inflammation in pediatric asthma patients.	26287664
Airway structure	Altered Intercellular Communication	Fractional concentration of exhaled nitric oxide (FeNO) is a known marker of airway inflammation.	26287987
Inflammation	Altered Intercellular Communication	These data indicate that 20 min of intradialytic exercise have modest effect in systemic inflammation.	26288101
Airway structure, Craniosynostosis	Altered Intercellular Communication	Fractionated exhaled nitric oxide (FeNO) levels were reportedly elevated in some asthmatics with CRS after adequate treatment, suggesting that residual eosinophilic airway inflammation or ECRS might affect FeNO levels.	26288109
airway disease, Asthma, Craniosynostosis, Eosinophilic inflammation	Altered Intercellular Communication	There is a possibility of having comorbid ECRS, particularly in asthmatics with high FeNO levels even after adequate treatment, including ICS, suggesting that asthma and ECRS may be closely associated as one airway disease with eosinophilic inflammation.	26288109
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD) may lead to reduced concentrations of high-density lipoprotein (HDL) and its subfractions (HDL2 and HDL3), and damage them via inflammation and oxidative stress.	26289085
Inflammation, Necrotizing Scleritis, Avascular Necrosis, CTCAE	Altered Intercellular Communication	Necrotizing scleritis is an immune-mediated ocular inflammatory process, characterized by an area of avascular necrosis and a profound inflammation of the sclera and episclera.	26290030
Intestinal metaplasia, Inflammation, Carditis, Atrophic	Altered Intercellular Communication	Histologically, the columnar epithelium of squamocolumnar junction, presence and severity of acute and chronic inflammation, atrophy, intestinal metaplasia, and presence of carditis were evaluated.	26290639
Inflammation, Carditis, Gastro-esophageal reflux disease with esophagitis, Certified Midwife	Altered Intercellular Communication	The inflammation of CM, "carditis", showed a statistically significant association with endoscopic diagnosis of reflux esophagitis according to the LA classification (P = 0.008).	26290639
Inflammation, Hemorrhage, Superficial ulcer, Numerous, Anastomosis - action, Edema, Exudate	Altered Intercellular Communication	Endoscopic examination revealed an anastomotic stricture; signs of inflammation, including redness, erosion, edema, bleeding, friability, and exudate with white plaques; and multiple depressions in the residual esophagus.	26290650
Inflammation	Altered Intercellular Communication	Seven weeks later, endoscopic examination revealed improvement in the mucosal inflammation; only the pseudodiverticulosis remained.	26290650
Inflammation, Stenosis	Altered Intercellular Communication	At the latest follow-up, the patient was symptom-free and the pseudodiverticulosis remained in the residual esophagus without any signs of stricture or inflammation.	26290650
Intestinal metaplasia, Inflammation, Calf muscle pseudohypertrophy	Altered Intercellular Communication	Upon review of these 18 biopsies, the most common histologic findings were heavy full-thickness or deep lamina propria chronic inflammation (12), inflammatory destruction of oxyntic glands (12), metaplasia (intestinal, pyloric, or pancreatic acinar) (10), prominent lamina propria eosinophils (8), and parietal cell pseudohypertrophy (4).	26291507
Inflammation, Metaplasia	Altered Intercellular Communication	When metaplasia, full-thickness chronic inflammation, and/or oxyntic destruction are seen, a note suggesting laboratory testing and/or close clinical follow-up in this subset of patients may be warranted.	26291507
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Increasing evidence suggests a close relationship between systemic inflammation and cancer development and progression.	26292807
Inflammation, Prostate carcinoma	Altered Intercellular Communication	We investigated the influence of markers of systemic inflammation such as leucocyte counts and metabolic co-morbidities on overall survival (OS) after radiotherapy for localized prostate cancer.	26292807
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Neutrophil count, as a possible marker of systemic inflammation, appear to be an independent prognostic factor for overall mortality in localized prostate cancer.	26292807
Inflammation, Psoriasis	Altered Intercellular Communication	RBP-4 might have a protective role in terms of chronic inflammation and comorbidities of psoriasis.	26293108
Inflammation, Impaired cognition, Data types - Address	Altered Intercellular Communication	The cognitive impairment caused by AD is associated with abnormal accumulation of amyloid-b (Ab) and hyperphosphorylated tau, which are accompanied by inflammation.	26293123
Primary malignant neoplasm, Chronic inflammation	Altered Intercellular Communication	Patients with chronic inflammation, such as cancer, have been shown to have pathological clot structures with modulated mechanical properties.	26293709
Inflammation, Behavior, Neoplasms	Altered Intercellular Communication	Nevertheless, the tumorous behavior points to a continuity between inflammation and neoplasia.	26293797
Gingivitis, Hemorrhage	Altered Intercellular Communication	One hundred twenty participants (non-dental students) with a moderate gingival inflammation (bleeding on probing at 40-70 % of test sites) were included in this randomized controlled double blind clinical trial.	26293981
Cytomegalovirus Infections, Inflammation	Altered Intercellular Communication	Histological features of CMV graft infection include: (1) stromal keratocytes with cytopathic changes; (2) lack of inflammation, only occasional macrophages present and (3) absence of vascularisation.	26294107
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Inflammation and the bone-vascular axis in end-stage renal disease.	26294291
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Parameters of inflammation and mineral metabolism were assessed in 81 ESRD patients (55 +- 13 year, 68 % male) referred for renal transplantation.	26294291
Inflammation, Calcification of the aorta, Diabetes Mellitus	Altered Intercellular Communication	Low bone area associated with aortic calcification, independent of age, diabetes, and inflammation.	26294291
Inflammation, Calcification of the aorta	Altered Intercellular Communication	Low bone area and inflammation associates with aortic calcification, independent of each other and traditional risk factors.	26294291
Schizophrenia, Inflammation	Altered Intercellular Communication	The chronic schizophrenia group showed significant elevations in the combined inflammation score compared with controls.	26294704
Schizophrenia, Inflammation	Altered Intercellular Communication	Consistent with these findings, the chronic schizophrenia group had significantly increased odds of a combined inflammation score greater than the 75th and the 90th percentile of that of the controls.	26294704
Inflammation, Atherosclerosis	Altered Intercellular Communication	Life course socioeconomic status and DNA methylation in genes related to stress reactivity and inflammation: The multi-ethnic study of atherosclerosis.	26295359
Inflammation, Prostatic Intraepithelial Neoplasias	Altered Intercellular Communication	Twelve biopsies yielded nonmalignant results (60%): high-grade prostatic intraepithelial neoplasia (n = 3) or benign prostatic tissue with or without inflammation (n = 9).	26295644
Intraocular inflammation, Edema	Altered Intercellular Communication	Associated ocular features included retinal pigment epithelial changes (67%), intraocular inflammation (55%), subretinal fluid (50%), macular edema (50%), and choroidal folds (30%).	26296144
Intraocular inflammation	Altered Intercellular Communication	It can produce intraocular inflammation in 50% of the cases and may be painless in 25%.	26296144
Gingivitis, Dental caries	Altered Intercellular Communication	Negative binomial regression model of permanent tooth caries found higher rates of caries in children who were from non-fluoridated areas (RR 2.1); Aboriginal (RR 2.4); had gingival inflammation (RR 1.5); lower ICSEA level (RR 1.4); and recalled at more than 24-month interval (RR 1.8).	26296432
Malignant tumor of colon, Inflammation, Neoplasms	Altered Intercellular Communication	In colon cancer, IL-17-driven inflammation promotes tumor progression, whereas IFN-g production is essential for antitumor immunity.	26297765
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Visfatin has been described as a marker of inflammation and endothelial dysfunction, but whether circulating visfatin levels are predictive to a subsequent decline in renal function remains unclear.	26298010
Inflammation	Altered Intercellular Communication	The diverticulum in our case appeared to have a thickened wall on imaging but no signs of acute inflammation were present on the CT scan or noticed intraoperatively.	26298012
Inflammation, Abscess	Altered Intercellular Communication	Ultimately, the surgical pathology revealed acute inflammation and focal abscess.	26298012
Inflammation, Hyponatremia	Altered Intercellular Communication	Hyponatremia was associated with inflammation, NT-proBNP, low muscle mass and alkaline phosphatase; these factors contributed to the increased total mortality associated with hyponatremia but did not explain the increased risk of CVD events associated with hyponatremia or low normal sodium concentration.	26298426
Inflammation, Refractory anemias, Autoimmune Diseases, Synovial joint structure, Rheumatoid Arthritis	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation and destruction of synovial joints.	26298564
Kidney Failure, Chronic, Inflammation, Sarcopenia, Cardiovascular Diseases	Altered Intercellular Communication	In end-stage renal disease, deleterious effect of sarcopenia on cardiovascular disease has been explained mainly by chronic inflammation.	26298738
Airway structure, Chronic Obstructive Airway Disease, Sleep Apnea, Obstructive	Altered Intercellular Communication	Obstructive sleep apnea exacerbates airway inflammation in patients with chronic obstructive pulmonary disease.	26298789
ARCN1 gene, Airway structure	Altered Intercellular Communication	It has an increased rate of hospitalization due to COPD exacerbation which is believed to indicate a worsening of the underlying chronic airway inflammation.	26298789
Airway structure, ARCN1 gene, Osage language	Altered Intercellular Communication	Therefore, the aim of this prospective study was to explore whether OSA exacerbates airway inflammation in subjects with COPD by examining the bronchoalveolar lavage (BAL) fluid.	26298789
Airway structure	Altered Intercellular Communication	After CPAP treatment, airway inflammation was found to decrease significantly.	26298789
Airway structure, Hypoxemia	Altered Intercellular Communication	CPAP treatment can improve nocturnal hypoxemia and decrease airway inflammation.	26298789
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Growing evidence indicated inflammation was linked to the progression and prognosis of many malignancies.	26299079
Inflammation, Thyroid Diseases, Malignant Neoplasms	Altered Intercellular Communication	Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), as two inflammation markers, reported frequently in the incidence and progress of solid cancers, but little research has concerned these markers in thyroid disease.	26299079
Edema of bone marrow	Altered Intercellular Communication	Fifty-six other RA-patients of the EAC-cohort underwent baseline MRIs of wrist, MCP and MTP-joints; MRI-inflammation (RAMRIS-synovitis plus bone marrow edema) was also evaluated in mediation analyses.	26299443
Damage	Altered Intercellular Communication	The association of age with joint damage (b=1.032, p=0.004) decreased after also including the MRI-inflammation-score (b=1.025, p=0.021), suggesting partial mediation.	26299443
Damage	Altered Intercellular Communication	RA-patients presenting at higher age have more severe joint damage; this might be partially explained by more severe MRI-detected inflammation at higher age.	26299443
Inflammation, Neoplasms	Altered Intercellular Communication	Chronic inflammation triggers DNA damage and oncogenic mutations and causes tumor formation and tumor progression.	26299699
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Beta-adrenergic receptor mediated inflammation control by monocytes is associated with blood pressure and risk factors for cardiovascular disease.	26300225
Amyotrophic Lateral Sclerosis	Altered Intercellular Communication	Complex Inflammation mRNA-Related Response in ALS Is Region Dependent.	26301107
Refractory anemias, Inflammation	Altered Intercellular Communication	Further, increased expression of Sema4A is required to promote inflammation of RA.	26303122
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	In people with type 2 diabetes, variations in the proportion of fat and carbohydrates of the diet, within the relatively narrow ranges recommended by different nutritional guidelines, significantly impact on the metabolic profile and markers of low-grade inflammation.	26303195
Inflammation, Hypoxia	Altered Intercellular Communication	The Human Carotid Body Gene Expression and Function in Signaling of Hypoxia and Inflammation.	26303502
Inflammation, Hypoxia	Altered Intercellular Communication	We conclude that by releasing pro- and anti-inflammatory cytokines during hypoxia the human carotid body displays a structural and functional capacity to participate in sensing and mediating systemic inflammation.	26303502
Ischemia, Thrombosis, Hemorrhage, Rupture, Meningitis	Altered Intercellular Communication	The mechanism appears to be the spread of meningeal inflammation to involve the walls of intracranial vessels, resulting in arterial thrombosis with ischemia or rupture with hemorrhage.	26304069
Inflammation, Carcinogenesis	Altered Intercellular Communication	Inflammation and oxidative stress play important roles in colorectal carcinogenesis.	26304464
Inflammation, Adenoma of large intestine	Altered Intercellular Communication	Overall, our results provide no evidence that calcium supplementation favorably modulates concentrations of circulating biomarkers of inflammation or oxidative stress over 4 months among patients with a previous colorectal adenoma.	26304464
Inflammation, Hypertension, CTCAE, Diarrhea	Altered Intercellular Communication	The most frequent AEs were diarrhea (cohort A, 74%; cohort B, 67%), mucosal inflammation (cohort A, 49%; cohort B, 60%), and hypertension (cohort A, 52%; cohort B, 45%).	26304872
Inflammation, Neuritis, Skin lesion, Swelling, physiopathological	Altered Intercellular Communication	Type 1 reactions are typical of borderline cases and occur in 30% of patients and present as swelling and inflammation of existing skin lesions, neuritis, and nerve dysfunction.	26304919
methyldopa, Inflammation, Blindness	Altered Intercellular Communication	Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the elderly of industrialized nations, and there is increasing evidence to support a role for chronic inflammation in its pathogenesis.	26305120
Gastrointestinal inflammation	Altered Intercellular Communication	FOXP3+ regulatory T cells (Tregs) are critical for preventing intestinal inflammation.	26305224
Radiofrequency Ablation, Inflammation, FAM126A gene	Altered Intercellular Communication	These data demonstrate that circulating histones are excessively released in HCC patients treated with RFA, which may lead to systemic inflammation by stimulating neutrophil activation and promoting cytokine production.	26305424
Radiofrequency Ablation, Inflammation	Altered Intercellular Communication	Circulating histones may act as a novel marker to indicate the extent of inflammation related to RFA.	26305424
Cataract	Altered Intercellular Communication	Molecular Inflammation in the Contralateral Eye After Cataract Surgery in the First Eye.	26305528
Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	Chronic prostatic inflammation (CPI) could be a cause of symptomatic or complicated benign prostatic hyperplasia (BPH).	26306400
Acute Coronary Syndrome, Cerebrovascular accident	Altered Intercellular Communication	Concurrent Carotid Inflammation in Acute Coronary Syndrome as Assessed by (18)F-FDG PET/CT: A Possible Mechanistic Link for Ischemic Stroke.	26306455
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	During follow-up, 3 cerebrovascular events occurred in ACS patients (including 1 early IS in a patient with severe baseline carotid inflammation), whereas none in CSA patients (P = .057).	26306455
GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	This study provided in vivo evidence that ACS survivors might experience concurrent carotid arterial inflammation.	26306455
Inflammation, physiopathological, Cardiovascular Diseases	Altered Intercellular Communication	Vascular endothelial function declines with advancing age, due in part to increased oxidative stress and inflammation, and this age-related vascular dysfunction has been identified as an independent risk factor for cardiovascular diseases.	26306566
Inflammation, Enophthalmos	Altered Intercellular Communication	CT showed right enophthalmos, a post-inflammatory change and chronic inflammation.	26306741
Inflammation, Atherosclerosis, Hyperglycemia, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation plays a critical role in the progression of atherosclerosis, and hyperglycemia is a common feature in patients with ACS.	26307104
Inflammation, GDC Disease Response Terminology	Altered Intercellular Communication	DR pathogenesis has not been fully elucidated, but inflammation is widely accepted to play an important role.	26308022
Inflammation	Altered Intercellular Communication	Chronic inflammation and oxidative stress might be considered the key mechanisms of aging.	26308091
palladium, Nerve Degeneration	Altered Intercellular Communication	However, the association between long-term systemic inflammations and neurodegeneration has not been assessed in PD patients.	26308525
palladium, Presenile dementia, Nerve Degeneration	Altered Intercellular Communication	These associations were independent of sex, age, PD severity, dementia, and anti-Parkinsonian agents, suggesting that subclinical systemic inflammations could accelerate neurodegeneration in PD.	26308525
Inflammation	Altered Intercellular Communication	The association between subgingival periodontal pathogens and systemic inflammation.	26309048
Inflammation, Periodontal Diseases	Altered Intercellular Communication	To investigate associations between periodontal disease pathogens and levels of systemic inflammation measured by C-reactive protein (CRP).	26309048
Inflammation	Altered Intercellular Communication	The association between interleukin 8 with nonphysical domains in patients with 6MWD < 350 m suggests that inflammation may play a larger role in the perceptive domain than previously recognized.	26309192
Inflammation, Myocardial	Altered Intercellular Communication	Abundant myocardial edema without evidence of acute inflammation was detected in cardiac tissue postmortem in one patient.	26310790
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	OA synovium was stratified by histological inflammation grade using index tissue sections.	26311062
Inflammation, Atherosclerosis	Altered Intercellular Communication	Arterial wall properties and inflammation are key players in atherosclerosis development.	26311225
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Role of inflammation in benign prostatic hyperplasia development among Han Chinese: A population-based and single-institutional analysis.	26311564
Asymptomatic Inflammatory Prostatitis, prostatitis	Altered Intercellular Communication	In terms of histopathological analysis, benign prostatic hyperplasia/asymptomatic inflammatory prostatitis patients were more likely to show mild (53%), focal (67%) and stromal (40%) prostatic inflammation in our study.	26311564
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Analysis of distribution and severity of inflammation in patients with osteoarthitis compared to rheumatoid arthritis by ICG-enhanced fluorescence optical imaging and musculoskeletal ultrasound: a pilot study.	26311723
Inflammation	Altered Intercellular Communication	Joint inflammation can be visualised by fluorescence optical imaging (FOI) and musculoskeletal ultrasound (US).	26311723
Inflammation	Altered Intercellular Communication	Joint inflammation was graded by a semiquantitative score (0-3) for each imaging method.	26311723
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	US and FOI detected inflammation in both RA and OA highlighting the inflammatory component in the course of OA.	26311723
Inflammation, Acute Cholecystitis	Altered Intercellular Communication	Imaging features of acute cholecystitis have been described in the literature and are variable, depending on the stage of inflammation.	26311909
Communicable Diseases, Lichen Sclerosus et Atrophicus	Altered Intercellular Communication	The etiology of lichen sclerosus is multifactorial, with participation of genetic, autoimmune, infectious and hormonal factors.	26312692
Polyarteritis Nodosa, Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Polyarteritis nodosa is a rare vasculitis in children characterized by necrotizing inflammation in small and medium size arteries.	26312712
Inflammation, Damage, Rheumatoid Arthritis	Altered Intercellular Communication	MRI evidence of persistent joint inflammation and progressive joint damage despite clinical remission during treatment of early rheumatoid arthritis.	26313244
Inflammation, Superficial ulcer	Altered Intercellular Communication	MRI at baseline detected inflammation in joints and tendons in all patients as well as erosions in 10 out of 13 patients.	26313244
Damage	Altered Intercellular Communication	The MRI changes showed that joint damage started early and continued in the presence of persistent synovial and tenosynovial inflammation.	26313244
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Inflammatory bowel disease (IBD) is characterized by a chronic inflammation of the gut, partly driven by defects in the innate immune system.	26313692
palladium, Inflammation, Malnutrition, Periodontal Diseases	Altered Intercellular Communication	Periodontal disease (PD) is prevalent and correlated with malnutrition and inflammation in patients on hemodialysis (HD).	26313800
Primary hypogonadism	Altered Intercellular Communication	The gonads also have poor hormonal activity (hypergonadotropic hypogonadism) in most of the pubertal/adult patients.	26314751
Refractory anemias, Inflammation, Rheumatoid Arthritis, Diabetes Mellitus	Altered Intercellular Communication	Low-grade inflammation conditions, e.g., type 2 diabetes, have been shown to be associated with an increased risk of rheumatoid arthritis (RA).	26314811
Dermatitis, Atopic, Asthma, IL13 gene	Altered Intercellular Communication	However, the association between other chronic inflammatory conditions, e.g., asthma, allergic rhinitis, and atopic dermatitis, is still unclear.	26314811
Inflammation, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	Previous studies have shown a relationship between obstructive sleep apnea (OSA) and erythrocyte sedimentation rate (ESR), a representative marker for inflammation.	26315467
Inflammation, Asthma, Allergic	Altered Intercellular Communication	Adiponectin does not protect against the development of inflammation in the setting of asthma and may in fact exacerbate the disease via its anti-TH1 inflammatory effects, allowing for increased TH2 differentiation and a more severe allergic response.	26315710
Inflammation, Brain	Altered Intercellular Communication	The gradually evolving focal neurological signs and underlying immunosuppression raised the possibility of localized cerebral infection or inflammation.	26315723
Cancer-related fatigue, Inflammation	Altered Intercellular Communication	There was no difference in PWV, cIMT, CRF or in markers of systemic inflammation in the patients with KD (CAA+ or CAA-) compared with HC.	26316045
Refractory anemias, Inflammation	Altered Intercellular Communication	We emphasize the unusual spontaneous and sustained joint remission without specific treatment, and the development of severe extra-articular manifestations of RA in absence of concomitant articular activity, as well as the importance of controlling inflammation.	26316106
Inflammation, Gastritis, Atrophic	Altered Intercellular Communication	Positive relationship between p42.3 gene and inflammation in chronic non-atrophic gastritis.	26316259
Stomach Carcinoma, Neoplasms	Altered Intercellular Communication	Gastric cancer (GC) is a typical type of inflammation-related tumor.	26316259
Gastritis	Altered Intercellular Communication	We aimed to explore the relationship between gastric inflammation and p42.3 gene in vitro and in vivo.	26316259
Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	In addition, p42.3 gene expression was positively associated with the severity of gastric mucosal inflammation and H. pylori infection (P = 0.000).	26316259
Gastritis	Altered Intercellular Communication	Its expression was significantly more common in severe gastric inflammation and in H. pylori-infected cases.	26316259
Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane	Altered Intercellular Communication	p42.3 gene expression is associated with gastric mucosal inflammation that can be upregulated by TNF-a and H. pylori infection.	26316259
Electrocardiogram: myocardial infarction (finding), atherosclerotic	Altered Intercellular Communication	Systemic Atherosclerotic Inflammation Following Acute Myocardial Infarction: Myocardial Infarction Begets Myocardial Infarction.	26316523
atherosclerotic	Altered Intercellular Communication	The presence and extent of MI is associated with increased aortic atherosclerotic inflammation and early recurrent MI.	26316523
Dental Plaque, atherosclerotic	Altered Intercellular Communication	This finding supports the hypothesis that acute MI exacerbates systemic atherosclerotic inflammation and remote plaque destabilization: MI begets MI.	26316523
Inflammation, Sleep Apnea, Obstructive, Endothelial dysfunction	Altered Intercellular Communication	There is growing research evidence suggesting the presence of endothelial dysfunction and systemic inflammation in patients with obstructive sleep apnea syndrome (OSAS).	26316731
Prediabetes syndrome, Bipolar Disorder	Altered Intercellular Communication	Hormonal determinants of the severity of andropausal and depressive symptoms in middle-aged and elderly men with prediabetes.	26316733
palladium, Bipolar Disorder	Altered Intercellular Communication	Hormonal determinants of andropausal and depressive symptoms are different in middle-aged and elderly patients, but endocrine tests are necessary in all men with PD.	26316733
Inflammatory Bowel Diseases, Inflammation, Leukocytosis, Fever, CTCAE, Primary Biliary Cholangitis, Cryopyrin-Associated Periodic Syndromes, "Sjogrens Syndrome", Arthritis, Juvenile-Onset Still Disease, Lupus Erythematosus	Altered Intercellular Communication	Included were cases of Schnitzler syndrome, Still disease, systemic lupus erythematosus, Sjogren syndrome, cryopyrin-associated periodic syndrome, primary biliary cirrhosis, inflammatory bowel disease, and those that had signs of systemic inflammation not otherwise specified, that is, fever, arthritis, leukocytosis, and elevated erythrocyte sedimentation rate.	26317390
Icterus, Inflammation, Illness (finding), TYPHUS	Altered Intercellular Communication	In murine typhus, nucleosome levels associated with pro-inflammatory cytokines and the duration of illness, while ELA complexes correlated strongly with inflammation markers, jaundice and increased respiratory rates.	26317419
Hyperglycemia, Inflammation, Hyperlipidemia, Atherosclerosis	Altered Intercellular Communication	Hyperglycemia, insulin resistance, dislipidemia, oxidative stress and inflammation are well-documented risk factors for subclinical atherosclerosis.	26318108
Hyperlipidemia, Inflammation	Altered Intercellular Communication	The ORs for insulin resistance, dislipidemia, oxidative stress and inflammation were higher with increasing DPP4 quartiles (P < 0.001 for trend).	26318108
Anxiety, CTCAE 3.0, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Participants completed self-reported measures of family and marital functioning, anxiety and depression (biobehavioral reactivity), number of chronic health conditions, number of prescribed medications, and a biological protocol in which the following indices were obtained: cardiovascular functioning, sympathetic and parasympathetic nervous system activity, hypothalamic pituitary adrenal axis activity, inflammation, lipid/fat metabolism, and glucose metabolism.	26318212
Cessation of life, Inflammation, Data types - Address	Altered Intercellular Communication	Multiple cellular processes including regulation of amyloid-b peptide, tau, inflammation, and cell death have been suggested to associate with AD, but it remains largely unknown if long noncoding RNAs (lncRNAs) may be playing a role in AD pathogenesis.	26318290
Inflammation, Restenosis	Altered Intercellular Communication	The molecular basis of restenosis is intensively associated with inflammation.	26318748
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	due to the relevance of inflammation in individuals with chronic kidney disease (CKD), inflammation should be taken into account in the interpretation of the clinical-nutritional status.	26319862
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	assess the association between inflammation, nutritional and clinical parameters in patients with CKD.	26319862
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	In the group with inflammation, 05 (33%) had hypoalbuminemia as compared with 05 (6.5%) in the group without inflammation (p = 0.002).	26319862
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	inflammation was associated with changes in the total cholesterol and LDL levels and with an increased incidence of hypoalbuminemia.	26319862
Postoperative endophthalmitis, Retinal Detachment, Acute inflammation, Suprachoroidal hemorrhage	Altered Intercellular Communication	There were no cases of postoperative endophthalmitis, suture erosion/breakage, retinal detachment, suprachoroidal haemorrhage, uveitis-glaucoma-hyphema syndrome or persistent postoperative inflammation in the follow-up period.	26319945
Inflammation, Injury of liver	Altered Intercellular Communication	Endocannabinoid System Contributes to Liver Injury and Inflammation by Activation of Bone Marrow-Derived Monocytes/Macrophages in a CB1-Dependent Manner.	26320250
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	In vivo, inhibition of CB1 attenuated the inflammatory cytokine level through real-time RT-PCR and cytometric bead array, ameliorating hepatic inflammation and fibrosis.	26320250
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	In this study, we identify inactivation of BMM-expressed CB1 as a therapeutic strategy for reducing hepatic inflammation and fibrosis.	26320250
Inflammation	Altered Intercellular Communication	As such, the cerebral capillary endothelium represents an important target for the peripheral estrogen neuroprotective functions, leading us to hypothesize that estrogen can limit BBB breakdown following the onset of peripheral inflammation.	26321046
Myelofibrosis, Colonization, Bone necrosis, Suppurative inflammation, Osteonecrosis of Jaw, Actinomyces	Altered Intercellular Communication	The typical histological aspects of ONJ were predominantly osteonecrosis, bone marrow fibrosis, and bacterial colonization (Actinomyces) with suppurative inflammation.	26321065
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by neutrophilic airway inflammation.	26321138
Airway structure	Altered Intercellular Communication	WNT/b-catenin signaling regulates cigarette smoke-induced airway inflammation via the PPARd/p38 pathway.	26322419
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The mechanisms of WNT/b-catenin signaling involved in airway inflammation of chronic obstructive pulmonary disease (COPD) remain unknown, although recent observations have suggested an important contribution of the pathway in pulmonary parenchymal tissue repair and airway epithelium differentiation.	26322419
Airway structure, ARCN1 gene	Altered Intercellular Communication	Taken together, our findings indicate that the reduced activity of WNT/b-catenin signaling induced by CS may promote inflammatory cytokine production in airway epithelium and have an essential role in airway inflammation in COPD by PPARd/p38 MAPK pathway.	26322419
Crohn Disease	Altered Intercellular Communication	Contrast Enhanced Abdominal Ultrasound in the Assessment of Ileal Inflammation in Crohn's Disease: A Comparison with MR Enterography.	26322970
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Optimal diagnostic accuracy in CEUS was obtained at a peak intensity value of 10%, showing 100% sensitivity, 92% specificity and an accuracy of 99% in demonstrating ileal mucosal inflammation.	26322970
Inflammation, Carcinogenesis	Altered Intercellular Communication	Chronic inflammation plays an important role in lung carcinogenesis.	26323323
Inflammation, Carcinoma of lung, Obesity	Altered Intercellular Communication	Few prospective studies have examined associations between lung cancer, serum C-reactive protein (CRP), a measure of systemic inflammation, and inflammatory lifestyle factors, such as smoking and obesity.	26323323
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Is the exhaled breath temperature in lung cancer influenced by airways neoangiogenesis or by inflammation?	26323590
Inflammation, Primary malignant neoplasm, Fatigue	Altered Intercellular Communication	Fatigue in Patients With Advanced Terminal Cancer Correlates With Inflammation, Poor Quality of Life and Sleep, and Anxiety/Depression.	26324072
Inflammation, Primary malignant neoplasm, Fatigue	Altered Intercellular Communication	In patients with advanced cancer, fatigue is a common symptom associated with the presence of inflammation, poor quality of sleep, depression/anxiety, and poor quality of life.	26324072
Inflammation, Anemia	Altered Intercellular Communication	Anemia in this setting appears multifactorial such that chronic inflammation and iron deficiency need to be addressed together as part of integrated management of childhood anemia.	26324733
Inflammation, Atrial Fibrillation, Hyperuricemia, Gout	Altered Intercellular Communication	Recent studies suggest an association between inflammation, hyperuricaemia and AF, but little is known whether gout is associated with AF risk.	26324846
Inflammation	Altered Intercellular Communication	The role of inflammation in psychopathology has received great attention over the past decades.	26325024
Inflammation, Psychiatric	Altered Intercellular Communication	Results show elevated inflammation markers from the innate immune system across C&A acute psychiatric diagnosis, and suggest a link between psychopathology, inflammation and stress.	26325024
Inflammation, Carcinogenesis	Altered Intercellular Communication	Immune response-related genes play a major role in colorectal carcinogenesis by mediating inflammation or immune-surveillance evasion.	26325386
PROS1 gene, Arthritis, Arthritis, Psoriatic	Altered Intercellular Communication	This study aims to evaluate the application of fIRI in Psoriatic Arthritis (PsA) assessment, evaluating the thermoregulatory alterations due to joint inflammation in PsA patients both in basal conditions and after a mild functional (isometric) exercise; fIRI outcomes were compared with those provided by Power Doppler Ultrasonography (PWD-US).	26327581
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Oxidative stress linked with chronic inflammation is associated with etiology of the colorectal cancer.	26329524
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Urinary DNA modifications may reflect the oxidative stress/chronic inflammation in colorectal cancer but diagnostic performance for early-detection is moderate.	26329524
Inflammation, Atresia, Tuberculosis	Altered Intercellular Communication	The atresia of the superior segmental bronchus was histologically considered to be acquired atresia due to the inflammation from tuberculosis.	26329627
Inflammation, Nephrotic Syndrome, Minimal Change	Altered Intercellular Communication	Inflammation is a key part in the etiology and progression of idiopathic nephrotic syndrome (INS), we hypothesize that removing pro-inflammatory cytokines with intermittent high-volume hemofiltration (IHVHF) could improve the outcome in INS patients.	26329674
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Long-Term Telbivudine Treatment Results in Resolution of Liver Inflammation and Fibrosis in Patients with Chronic Hepatitis B.	26329749
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	After antiviral treatment (median duration: 261 weeks), liver histology improved with increased proportions of patients with absence/minimal liver inflammation (Knodell necroinflammatory score <=3), from 16% (9/57) at baseline to 98% (56/57), and absence/minimal fibrosis (Ishak score <=1), from 25% (14/57) at baseline to 84% (48/57).	26329749
Gastrointestinal inflammation, Visceral Pain	Altered Intercellular Communication	Recent studies implicate TRPV4 receptors in visceral pain signaling and intestinal inflammation.	26330151
Pain Distress Question, Gastrointestinal inflammation	Altered Intercellular Communication	* Recent studies implicate TRPV4 in pain signaling and intestinal inflammation.	26330151
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The matrix metalloproteinase-7 (MMP-7) and osteopontin (OPN) are both multifunctional proteins with roles in inflammation, cell proliferation, tissue remodeling and so on, implicated in the pathogenesis of numerous conditions including pulmonary fibrosis.	26330178
methyldopa, Inflammation	Altered Intercellular Communication	The pathogenesis of age-related macular degeneration (AMD) is associated with systemic and local inflammation.	26330750
Retinitis, Bacterial Infections	Altered Intercellular Communication	Various studies suggested that viral or bacterial infection may aggravate retinal inflammation in the aged retina.	26330750
Retinitis	Altered Intercellular Communication	The data also suggest that selective inhibition of distinct signal transduction pathways or individual transcription factors may not be effective to inhibit viral retinal inflammation.	26330750
Inflammation, Neoplasms	Altered Intercellular Communication	CD4 (+) T helper 17 (Th17) cells play critical roles in inflammation and tumor development.	26331819
Chronic Obstructive Airway Disease, Carcinoma of lung	Altered Intercellular Communication	The involvement of Th17 cells in chronic obstructive pulmonary disease (COPD)-type inflammation-associated lung cancer has also been confirmed in animal models.	26331819
Inflammation, Hyperferritinaemia, Malignant Neoplasms	Altered Intercellular Communication	Hyperferritinemia is common in states of iron overload, inflammation, and malignancy.	26332484
Inflammation	Altered Intercellular Communication	Uncontrolled complement activation and the release of cell-free heme may result in systemic inflammation, neutrophil activation, and the release of procoagulant neutrophilic proteases.	26333021
Paroxysmal nocturnal hemoglobinuria, Thrombosis, Inflammation, Cell Death	Altered Intercellular Communication	The increased nucleosome levels in PNH patients with a history of thrombosis suggest systemic inflammation and/or cell death.	26333021
Primary sclerosing cholangitis, Inflammation, Fibrosis Assessment, Injury of bile duct	Altered Intercellular Communication	Primary sclerosing cholangitis (PSC) is characterized histologically by portal inflammation, bile duct injury and regeneration and concentric periductal fibrosis.	26333410
Inflammation, Calcinosis, Epithelial cyst	Altered Intercellular Communication	The patients we examined all had scrotal epidermoid cysts in varying stages of inflammation coexisted with scrotal calcinosis.	26333550
Inflammation, Villous atrophy	Altered Intercellular Communication	It is characterized by chronic inflammation of small intestine associated with villous atrophy.	26333587
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	B. pseudocatenulatum CECT7765 induces a morphologic, phenotypic and functional transition towards an anti-inflammatory profile in GM-CSF monocyte-derived and AF macrophages from patients with cirrhosis that may help in controlling sustained inflammation in decompensated cirrhosis.	26334579
RETINOSCHISIS 1, X-LINKED, JUVENILE	Altered Intercellular Communication	Resistant starch (RS) decreases intestinal inflammation in some settings.	26334878
RETINOSCHISIS 1, X-LINKED, JUVENILE, Inflammation	Altered Intercellular Communication	We tested the hypothesis that gut inflammation will be reduced with dietary supplementation with RS in rural Malawian children.	26334878
RETINOSCHISIS 1, X-LINKED, JUVENILE, Inflammation	Altered Intercellular Communication	Our findings do not support the hypothesis that RS reduces gut inflammation in rural Malawian children.	26334878
Inflammation, Vascular calcification, Calcinosis, Cerebral Atherosclerosis, Arterial Stiffness	Altered Intercellular Communication	This occurs not only due to hemodynamic factors but also by systemic ones related to vascular atherosclerosis, inflammation and calcification, which has developed a simple vascular calcification score (SVCS) predictor of vascular calcification and arterial stiffness.	26336882
Demographics Domain, "Alzheimers Disease", Data types - Address, Inflammation Mediators, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The aim of the present study was to evaluate whether there was an inflammation-mediated link between Alzheimer's disease (AD) and type 2 diabetes mellitus (DM) status.	26337250
Inflammation, Tumor necrosis	Altered Intercellular Communication	Serum inflammation status was evaluated by the determination of serum C-reactive protein (CRP), tumor necrosis factor-alpha, interleukin (IL)-1b and IL-6 levels.	26337250
Inflammation, Data types - Address	Altered Intercellular Communication	Our findings support the presence of a low-grade systemic inflammation link between AD and DM.	26337250
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The identified genetic variants imply contribution of biological pathways observed in osteoarthritis as well as new pathways, influencing skeletal development and inflammation.	26337638
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	MicroRNA (miR)-146a and miR-21 have been reported to participate in inflammatory reactions and fibrosis.Excessive inflammation and cardiac fibrosis may play important roles in the development of left ventricular remodeling(LVR).	26337652
Connective Tissue Diseases	Altered Intercellular Communication	Patients with known connective tissue disorders, systemic inflammatory conditions, dissection, or prior heart surgery were excluded.	26338050
Abnormal renal function, Inflammation	Altered Intercellular Communication	Hemodialysis patients face oxidative stress and inflammation induced by both kidney dysfunction and hemodialysis procedure.	26338165
Sepsis, Inflammation, Traumatic injury	Altered Intercellular Communication	Burn injuries are associated with strong inflammation and risk of secondary sepsis which both may affect the function of the glucocorticoid receptor (GR).	26338204
Refractory anemias, Inflammation	Altered Intercellular Communication	To investigate the effect of suppressing inflammation on retinal microvascular health in patients with RA.	26338663
Refractory anemias, Inflammation	Altered Intercellular Communication	We demonstrated that suppression of inflammation in RA is associated with a reduction of retinal venular calibre, suggesting that therapies targeting inflammation could improve vascular health in RA.	26338663
Crohn Disease, Inflammation	Altered Intercellular Communication	This study supports the hypothesis that in Crohn's disease, enteric neurons and glial cells form a functional unit reacting to inflammation by producing PGD2.	26338799
Crohn Disease	Altered Intercellular Communication	We investigated the expression of PGD2 metabolic pathway actors in Crohn's disease (CD) and the ability of the enteric nervous system (ENS) to produce PGD2 in inflammatory conditions.	26338799
Inflammation, Endothelium, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8, GDC Disease Response Terminology	Altered Intercellular Communication	The circulating markers of inflammation, endothelial injury, and TNF signaling are significantly associated with DR in patients with T1D.	26339132
Refractory anemias, Inflammation, BDI - Functional Impairment, GRN wt Allele	Altered Intercellular Communication	This study demonstrates increased PGRN expression at local sites of inflammation and association between PGRN levels, disease activity, and functional impairment in patients with RA.	26339140
ARCN1 gene, Inflammation	Altered Intercellular Communication	Although COPD patients exhibited increased inflammation it was not associated with serum retinol.	26339144
Inflammation, Heart failure, Myocarditis, CTCAE 5.0, Shock, Cardiogenic	Altered Intercellular Communication	Fulminant myocarditis has been defined as the clinical manifestation of cardiac inflammation with rapid-onset heart failure and cardiogenic shock.	26339181
Peripheral Vascular Diseases, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Effects of percutaneous lower-extremity arterial interventions on endothelial function and inflammation response in patients with both type 2 diabetes and lower-extremity peripheral arterial disease.	26339379
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Fecal lactoferrin, a marker of intestinal inflammation in children with inflammatory bowel disease.	26339799
Inflammation, Malnutrition	Altered Intercellular Communication	Multivariate Cox proportional analysis showed that the hazards ratio for all-cause mortality was 1.02 (95% CI 1.01-1.04, p=0.006) per 1 mg/l increase in b2-M after adjustment for multiple confounding factors that relate to malnutrition and inflammation marker.	26339999
Inflammation, Meningitis	Altered Intercellular Communication	These findings suggest that TAFI plays an important role during pneumococcal meningitis, which is likely to be mediated through inhibition of the complement system, and influences the occurrence of systemic complications and inflammation.	26340319
Inflammation, Primary malignant neoplasm, Cardiovascular Diseases	Altered Intercellular Communication	The concentration, origin and procoagulant properties of circulating microparticles are reported to differ according to pathological settings (inflammation, cancer and cardiovascular diseases).	26341361
ARCN1 gene, Inflammation	Altered Intercellular Communication	Effective NPPV impacts on systemic inflammation in COPD patients.	26341549
Cerebral Amyloid Angiopathy, Inflammation, Cerebral microbleeds	Altered Intercellular Communication	The aim of this study is to describe a case of pathologically proven cerebral amyloid angiopathy-related inflammation (CAA-I) without cerebral microbleeds (CMBs) and its clinical course.	26341733
Inflammation, Fibrosis Assessment, Balloon Dilatation	Altered Intercellular Communication	Thirty-eight (74.5 %) patients had inflammation and 48 (94.1 %) had ballooning degeneration on histology; 29 had fibrosis, of whom 11 had >=F2 fibrosis.	26341864
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Markers of systemic inflammation are correlated with patient survival in various cancers.	26341881
Inflammation, Giant Cell Arteritis	Altered Intercellular Communication	MicroRNA markers of inflammation and remodelling in temporal arteries from patients with giant cell arteritis.	26342092
Sepsis, Inflammation	Altered Intercellular Communication	IL-35 is elevated in clinical and experimental sepsis and mediates inflammation.	26342538
Communicable Diseases, Inflammation, Carcinoma of lung	Altered Intercellular Communication	Interleukin (IL)-33 protects against infection and inflammation; however, few studies have explored the relevance of IL-33 in lung cancer patients.	26342550
Inflammation	Altered Intercellular Communication	Decreased effectiveness of ischemic heart preconditioning in the state of chronic inflammation.	26342834
Inflammation, Osage language, Atherosclerosis, Hypoxia, physiopathological, Sleep Apnea, Obstructive	Altered Intercellular Communication	Obstructive sleep apnea (OSA) is characterized by repetitive intermittent hypoxia and reoxygenation during sleep with elevated oxidative stress and promotes the development of atherosclerosis, as demonstrated by vascular dysfunction and chronic inflammation.	26343754
Inflammation	Altered Intercellular Communication	An increased neutrophil to lymphocyte ratio (NLR) has been recognized to be a novel inflammatory biomarker for systemic inflammation.	26343754
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The role of endothelial dysfunction and inflammation in this pathophysiological process is not yet clear.	26343780
ARCN1 gene, Inflammation	Altered Intercellular Communication	Our results showed negative association between peripheral muscle mass (evaluated by CT) and muscle strength and that systemic inflammation has a negative influence in the strength of specific groups of muscles in individuals with stable COPD.	26345641
Inflammation, Data types - Address	Altered Intercellular Communication	In conclusion, PS decreased cholinesterase, improved memory, and improved hippocampal inflammation injury in AD brains by increasing SOD and OH(-) levels.	26345866
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	EBV replication induced by chronic inflammation in patients with autoimmune diseases might explain the higher risk of EBV-positive HL.	26346543
Inflammation, Prediabetes syndrome, Sensory neuropathy, Diabetes Mellitus	Altered Intercellular Communication	Role of inflammation in sensory neuropathy in prediabetes or diabetes.	26346888
Inflammation, Neuropathy, Prediabetes syndrome, Peripheral Neuropathy	Altered Intercellular Communication	The pro-inflammatory stage and the high incidence of neuropathy in patients with prediabetes may suggest a possible causative effect; however, the potential role of inflammation in the pathogenesis of peripheral neuropathy needs further clarification.	26346888
Inflammation, Tracheobronchial	Altered Intercellular Communication	A postmortem examination with histology found evidence of active and chronic inflammation as well as destruction of cartilage, in keeping with a diagnosis of relapsing tracheobronchial polychonditis.	26347233
Inflammation, Lung Diseases, Interstitial	Altered Intercellular Communication	Childhood interstitial lung diseases are rare disorders of largely unknown etiology characterized by variable types and degrees of parenchymal inflammation.	26347438
Inflammation, Liver Dysfunction	Altered Intercellular Communication	However, IGF-1 is reduced by factors such as inflammation, oxidative stress and liver dysfunction.	26348017
Inflammation, Liver Dysfunction, Metabolic Syndrome X	Altered Intercellular Communication	But the relationship was dependent on oxidative stress, liver dysfunction and inflammation, suggesting underlying processes by which the metabolic syndrome attenuates IGF-1.	26348017
Ear Inflammation	Altered Intercellular Communication	Influence of Pneumococcal Conjugate Vaccine on Acute Otitis Media with Severe Middle Ear Inflammation: A Retrospective Multicenter Study.	26348230
Inflammation, Acute otitis media	Altered Intercellular Communication	In addition, this vaccine may help prevent acute otitis media with severe middle ear inflammation in 1-year-old infants.	26348230
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Increased oxidative stress and chronic inflammation participate in the pathogenesis of diabetes.	26348351
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Our results provide genetic evidence for a functional cross-talk of Nrf2 and NF-kB/RelA in hepatocytes, which protects the liver from necrosis, inflammation and fibrosis.	26348541
Typhlitis, Diarrhea	Altered Intercellular Communication	At baseline, Tox-/PCR+ patients had lower C difficile bacterial load and less antibiotic exposure, fecal inflammation, and diarrhea than Tox+/PCR+ patients (P < .001 for all).	26348734
Inflammation, Primary malignant neoplasm, Malignant Pulmonary Vein Neoplasm	Altered Intercellular Communication	There is a well-established link between inflammation and cancer of various organs, but little data are available on inflammation-associated markers of diagnostic and prognostic clinical utility in pulmonary malignancy.	26348770
Inflammation	Altered Intercellular Communication	MIF mRNA expression was increased in acutely inflamed adipose tissue indicating the activation of MIF gene transcription in response to adipose tissue inflammation.	26348853
Inflammation	Altered Intercellular Communication	Our results indicate that increased MIF expression and rapid activation of the MIF gene in fat tissue adjacent to acute wound healing disorders may play a role in cell recruitment to the site of inflammation and wound healing.	26348853
Sepsis, Inflammation	Altered Intercellular Communication	Hemoadsorption using CytoSorb has gained attention as a potential immunotherapy to control systemic inflammation and sepsis.	26349530
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Prospective data from the Women's Health Initiative on depressive symptoms, stress, and inflammation.	26349616
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Combined with previous research, this suggests the relationship between depression, stressful life events and inflammation attenuates with time.	26349616
Inflammation	Altered Intercellular Communication	Postinfectious, chronic inflammation of the retroperitoneum acts on the ureteral and peri-ureteral tissues, inducing an inflammatory and then a fibrotic process.	26350043
Blood Glucose, Diabetes Mellitus	Altered Intercellular Communication	Fluctuation in glycemia due to hormonal changes, growth periods, physical activity, and emotions make diabetes management difficult during adolescence.	26350209
Inflammation, Traumatic injury	Altered Intercellular Communication	These changes reflect apparently platelet response to the inflammatory process associated with the surgical trauma and confirm the role of NOx as a mediator of inflammation.	26350744
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Mechanistic links shared by T2D, AId and life-style factors such as obesity, perhaps through chronic inflammation, may drive autoimmune activation of T2D and many AIds.	26350756
Inflammation, Nerve Degeneration	Altered Intercellular Communication	This second part shows that immunological phenomena are increasingly more present in the pathogenesis of the disease, and that the interaction between inflammation and neurodegeneration is becoming more apparent.	26350778
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver biopsy samples from patients were obtained and used to calculate the METAVIR score to define the stage of fibrosis and inflammation grade.	26350896
Inflammation, Pancreatic carcinoma	Altered Intercellular Communication	Ruxolitinib plus capecitabine was generally well tolerated and may improve survival in patients with metastatic pancreatic cancer and evidence of systemic inflammation.	26351344
Inflammation, Osteoporosis, Cardiovascular morbidity	Altered Intercellular Communication	Records included demographics, inflammation markers, SpA clinical characteristics, treatment regimes, associated osteoporosis and cardiovascular morbidity.	26351533
Inflammation, Nephritis, ENL Protein, Neuritis, Osteitis, Skin lesion, Lymphadenitis, Dactylitis, Arthritis, Orchitis	Altered Intercellular Communication	ENL is associated with skin lesions, neuritis, arthritis, dactylitis, eye inflammation, osteitis, orchitis, lymphadenitis and nephritis.	26351858
Autoimmune Diseases, Communicable Diseases, Neoplasms	Altered Intercellular Communication	Interleukin-17A-producing T cells (IL-17A+ T) (IL-17A+CD4+ Th17, IL-17A+CD8+ Tc17 and IL-17A+ gdT17 cells) and associated cytokines (IL-17A, IL-23 and IL-1b) play crucial roles in inflammation-associated diseases, such as infection, autoimmunity and tumors.	26352729
Inflammation, Necrosis	Altered Intercellular Communication	No evidence of inflammation, cartilaginous vascularization, or necrosis was identified in any graft.	26352748
Inflammation, Necrosis	Altered Intercellular Communication	Mild to moderate degrees of chondrocytic dropout in the absence of necrosis and inflammation are probably attributable to the thick and coarsely textured collagen of the fibrous pseudoperichondrial capsule that may impede diffusion of nutrients into the center of the graft.	26352748
Inflammation, PDR gene, Diabetic Retinopathy, Diabetes Mellitus	Altered Intercellular Communication	Macrophages are involved in low-grade inflammation in diabetes, and play pathogenic roles in proliferative diabetic retinopathy (PDR) by producing proinflammatory cytokines.	26352837
Airway structure, Pain Distress Question, Laryngeal Edema	Altered Intercellular Communication	Three months after the therapy, the patient had an upper airway inflammation, and then laryngeal edema and pain occurred.	26355161
Inflammation, Colorectal Neoplasms, Ulcerative Colitis	Altered Intercellular Communication	Patients with ulcerative colitis (UC) are at increased risk of colorectal neoplasia (CRN) presumably because of chronic inflammation.	26355468
Inflammation, HIV-1 Infection Pathway, Dysbiosis	Altered Intercellular Communication	HIV-1 infection is characterized by altered intestinal barrier, gut microbiota dysbiosis, and systemic inflammation.	26355675
Inflammation	Altered Intercellular Communication	10 units increase in PAC-score was associated with 5-8% decrease in the likelihood of higher low-grade inflammation status (i.e.	26355794
Brain Injuries	Altered Intercellular Communication	[Clinical syndromes of neurotransmitter system dysfunction in severe brain injury].	26356514
Deficit	Altered Intercellular Communication	The following clinical syndromes of neurotransmitter system dysfunction were singled out: excess or insufficiency of glutamate, cholinergic deficit, excess or insufficiency of dopamine.	26356514
Sleep-Disordered Breathing, Inflammation	Altered Intercellular Communication	Sleep Related Breathing Disorders and Inflammation - The Missing Link?	26356577
Double-Stranded RNA Binding Motif, Inflammation, Obesity, Abnormal breathing	Altered Intercellular Communication	Sleep related breathing disorders (SRBD) are associated with both obesity and systemic inflammation.	26356577
Double-Stranded RNA Binding Motif, Inflammation, Obesity	Altered Intercellular Communication	While the relationship between obesity and SRBD is established, the causality between inflammation and SRBD remains unclear.	26356577
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Local and systemic inflammation often present in chronic obstructive pulmonary disease (COPD).	26356719
ARCN1 gene, Inflammation	Altered Intercellular Communication	In conclusion, circulating CTRP-5 was associated with the severity of airflow obstruction and systemic inflammation in patients with COPD, which suggests that it may be used as a potential novel inflammatory biomarker in COPD.	26356719
Inflammation, Depression, CTCAE, Psychiatric	Altered Intercellular Communication	Inflammation and depression: combined use of selective serotonin reuptake inhibitors and NSAIDs or paracetamol and psychiatric outcomes.	26357585
Arterial Stiffness, Inflammation, ETV3 wt Allele, Atherosclerosis	Altered Intercellular Communication	MetS may contribute to the development of atherosclerosis by significantly increasing inflammation levels and arterial stiffness and decreasing circulating EPCs.	26359174
Sarcopenia	Altered Intercellular Communication	Although the "anti-aging hormone" klotho is associated with sarcopenia in mice, the relationship between klotho and muscle strength in older adults is not well known.	26359247
Inflammation, Neuromyelitis Optica, Cerebral atrophy	Altered Intercellular Communication	However, severe intrathecal inflammation and massive destruction of neuroglia could cause a secondary progressive clinical course associated with cerebral atrophy in neuromyelitis optica patients.	26359279
Coughing	Altered Intercellular Communication	A 46-year-old woman presented with cough for over 20 days, unrelieved by anti-inflammation treatment.	26359558
Inflammation, Retractile Mesenteritis	Altered Intercellular Communication	Biopsy of the mesentery revealed xanthogranulomatous inflammation, consistent with sclerosing mesenteritis.	26359565
Degenerative polyarthritis, Inflammation, Obesity	Altered Intercellular Communication	These findings highlight an important link between obesity and inflammation in knee osteoarthritis.	26359653
Inflammatory Bowel Diseases, Gastrointestinal inflammation, Intestinal Diseases	Altered Intercellular Communication	Fecal calprotectin is a noninvasive marker of intestinal inflammation used to distinguish between functional and organic bowel diseases and to evaluate disease activity among patients with Inflammatory Bowel Disease (IBD).	26359672
Hyperthyroidism, Levator palpebrae superioris structure	Altered Intercellular Communication	A 78-year-old woman with quiescent hyperthyroidism had clinical and radiological evidence of levator palpebrae superioris inflammation without superior rectus involvement.	26359702
Inflammation, Loss of facial adipose tissue, muscle mass	Altered Intercellular Communication	Anti-Fn14 antibodies prevented tumor-induced inflammation and loss of fat and muscle mass.	26359988
Inflammatory Bowel Diseases, Inflammation, Increase	Altered Intercellular Communication	The chronic inflammation of the intestinal mucosa, the extra-intestinal manifestations of the disease and the immunosuppressive treatment of inflammatory bowel disease may increase cancer risk.	26361018
Inflammation	Altered Intercellular Communication	Histopathological analysis of the bioptic pericardium showed a specific chronic inflammation.	26361701
Inflammation, Traumatic injury	Altered Intercellular Communication	Both blood exposure and trauma are known to induce cell death and inflammation and to enhance proteoglycan release in cartilage.	26362437
Inflammation, Inflammatory disorder	Altered Intercellular Communication	'Relapsing-remitting tumefactive inflammation' seems to have the features of a distinct inflammatory CNS disease.	26362889
Inflammation, Atherosclerosis	Altered Intercellular Communication	In conclusion, o-6-rHDL and o-3-rHDL show different physiological activities in atherosclerosis, inflammation, and cellular senescence.	26363928
Hyperglycemia, Inflammation	Altered Intercellular Communication	Our results showed the association of hyperglycemia with increased DNA damage and aberrant expression of miRNAs and genes related to several biological processes, such as inflammation, DNA repair, ROS production and antioxidant defense, highlighting the importance of proper glycemic control.	26364207
AATF wt Allele, Dry Eye Syndromes	Altered Intercellular Communication	Lifitegrast is an integrin antagonist that decreases T-cell-mediated inflammation associated with dry eye disease (DED).	26365210
Inflammation, Gastrointestinal dysfunction, Dysbiosis, Irritable Bowel Syndrome	Altered Intercellular Communication	Microbial dysbiosis and prolonged immune activation resulting in low-grade inflammation and intestinal barrier dysfunction have been suggested to be underlying causes of post-infectious irritable bowel syndrome (PI-IBS).	26366730
Epithelial hyperplasia, Pneumonitis	Altered Intercellular Communication	Importantly, pulmonary interstitial inflammation and epithelial hyperplasia that were significantly elevated in immunosuppressed animals were reduced by RI-002 administration.	26367224
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Main determinants for APD resistance were a worse control of the diabetes and higher baseline levels of inflammation (mean CRP 26.4 +- 56.0 vs. 9.3 +- 21.0; p < 0.01).	26367525
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	However, the high frequency of APD resistance and its association with inflammation and stroke severity are confirmed.	26367525
Communicable Diseases, PLEURAL EFFUSION, BLOODY, Inflammation, Hemoptysis	Altered Intercellular Communication	Intravenous administration of antibiotics and thoracic drainage successfully controlled the infection and inflammation until day 16, when the patient began to exhibit hemoptysis and bloody pleural effusion.	26369260
Granulomatous inflammation	Altered Intercellular Communication	Biopsy samples obtained from the right upper and left lower paratracheal nodes by mediastinoscopy revealed granulomatous inflammation.	26369493
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	The association of MetS with elevated IL-1beta level suggests that inflammation plays an important role in its pathogenesis.	26370103
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	We assessed associations among glycemic control, inflammation, and CP with cerebral structure on MRI and with cognitive performance in 268 high-risk African Americans with type 2 diabetes.	26370382
Cessation of life, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	The predictive value of HDL particle subclasses and inflammatory markers was studied for noncardiovascular, noncancer chronic inflammation-related death and hospitalization, and for incident cardiovascular disease (CVD).	26370448
Cessation of life	Altered Intercellular Communication	Small- plus medium-diameter HDL particles were inversely associated with diagnostic code-based noncardiovascular, noncancer chronic inflammation-related death and hospitalization (n=1054) independent of covariates: relative risk per SD 0.85 (95% CI: 0.79 to 0.91, P<0.0001).	26370448
Cessation of life, Coronary heart disease	Altered Intercellular Communication	Small- plus medium-diameter HDL particles are an independent predictor for noncardiovascular, noncancer chronic inflammation-related death and hospitalization and for coronary heart disease events in subjects initially free of overt CVD.	26370448
Inflammation	Altered Intercellular Communication	Corticosteroids may be able to successfully treat such inflammation or disruption of the blood ocular barrier.	26370869
Diego blood group system, Colitis	Altered Intercellular Communication	The hypothesis is that DI constituted a source of colonic inflammation, sending out bacterial antigenic stimuli that resulted in PG through deposition of circulating immune complexes.	26372545
Airway structure	Altered Intercellular Communication	Serum chitinases may be novel biomarkers of airway inflammation and remodeling, but less is known about factors regulating their levels.	26372680
Granulomatosis, Orofacial, Inflammation, Pathology	Altered Intercellular Communication	Orofacial granulomatosis represents a group of pathologies characterized by a granulomatous inflammation of the face and the oral mucosa.	26372981
Inflammation, Pathology	Altered Intercellular Communication	Since the macrocheilitis resulting from an inflammation could be associated to different pathologies, an accurate diagnosis has to be established.	26372981
Refractory anemias, Inflammation	Altered Intercellular Communication	Active RA (28-joint Disease Activity Score >= 2.6: OR 3.4, 95% CI 1.3-9.8) was an independent risk factor of HF, as well as systemic inflammation (erythrocyte sedimentation rate > 16 mm/h: OR 5.4, 95% CI 2.1-16; C-reactive protein > 10 mg/l: OR 2.6, 95% CI 0.8-8.0) and RA duration > 10 years (OR 2.6, 95% CI 1.2-5.8).	26373561
Refractory anemias, Inflammation	Altered Intercellular Communication	These results suggest that calprotectin might be superior to CRP for monitoring ultrasound-determined synovial inflammation in RA patients.	26373925
vascular inflammations	Altered Intercellular Communication	ERN/LRP reduces LDL-associated mediators of vascular inflammation, but has varied effects on HDL functionality and LDL quality, which may counter its HDL-C-raising effect.	26374297
Airway structure	Altered Intercellular Communication	She had additional airway inflammation leading to a TEF at the site of esophageal ulceration, requiring tracheostomy.	26374667
Inflammation, IgG4-Related Sclerosing Disease	Altered Intercellular Communication	Role of interleukin-32 in the mechanism of chronic inflammation in IgG4-related disease and as a predictive biomarker for drug-free remission.	26375328
Inflammation	Altered Intercellular Communication	In immunoglobulin (Ig) G4-related disease (IgG4-RD), the mechanism of chronic inflammation and predictive factors for drug-free remission is still unclear.	26375328
Inflammation	Altered Intercellular Communication	A characteristic pattern of symmetrical, extracapsular inflammation, adjacent to greater trochanter, acetabulum, ischial tuberosity and/or symphysis pubis, was observed in 14/22 of the PMR cases.	26376658
Inflammation	Altered Intercellular Communication	A subset of patients with rheumatologist-diagnosed PMR had a characteristic, extracapsular pattern of MRI inflammation, associated with elevated IL-6/CRP and with complete patient-reported glucocorticoid responsiveness.	26376658
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Moreover, a LC-MS/MS approach revealed 49 serum proteins with different abundances between healthy donors and cancer patients (predominantly proteins associated with inflammation and acute phase response).	26376850
Inflammation, Periodontitis, Sleeplessness	Altered Intercellular Communication	Periodontitis causes chronic discomfort and inflammation, and little is known about its impact on insomnia.	26377351
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Regulatory B cells (Bregs) play a critical role in inflammation and autoimmune disease.	26378021
Inflammation, Social security number, Leukoplakia	Altered Intercellular Communication	Signs more frequent in OSSN included feeder vessels (odds ratio [OR], 5.8 [95% CI, 3.2-10.5]), moderate inflammation (OR, 3.5 [95% CI, 1.8-6.8]), corneal involvement (OR, 2.7 [95% CI, 1.8-4.0]), leukoplakia (OR, 2.6 [95% CI, 1.7-3.9]), papilliform surface (OR, 2.1 [95% CI, 1.3-3.5]), pigmentation (OR, 1.5 [95% CI, 1.0-2.2]), temporal location (OR, 2.0 [95% CI, 1.2-3.2]), circumlimbal location (6.7% vs 0.3%; P < .001), severe inflammation (6.7% vs 0.3%; P < .001), and larger mean (SD) diameter (6.8 [3.2] vs 4.8 [2.8] mm; P < .001).	26378395
Inflammation	Altered Intercellular Communication	As exercise is associated with reduced systemic inflammation, we hypothesized that suppression of the pro-inflammatory transcription factor nuclear factor k B (NFkB) may mediate this process.	26378681
IgG4-Related Sclerosing Disease, Scleritis	Altered Intercellular Communication	Recent investigation suggests that many cases of sclerosing orbital inflammation are a manifestation of IgG4-related disease; however, most patients reported have been Asian, and it is not clear whether the results of studies from the Far East can be reliably extrapolated to draw conclusions about Western patients.	26379149
Soft tissues of orbit, Chronic dacryoadenitis, Orbital Pseudotumor, Scleritis	Altered Intercellular Communication	We evaluated 38 cases previously diagnosed as orbital inflammatory pseudotumor or chronic dacryoadenitis to determine whether our cases fulfill the criteria for IgG4-RD (IgG4-related dacryoadenitis when involving the lacrimal gland, and IgG4-related sclerosing orbital inflammation when involving orbital soft tissue).	26379149
Dacryoadenitis, Orbital Pseudotumor	Altered Intercellular Communication	Fifteen patients had IgG4-related dacryoadenitis or orbital inflammation.	26379149
Inflammation, Granulomatosis, Fibrosis Assessment, Systemic Vasculitis, Disease	Altered Intercellular Communication	These patients had a variety of diseases, including granulomatosis with polyangiitis (3 cases), Rosai-Dorfman disease (1 case), nonspecific chronic inflammation and fibrosis involving lacrimal gland or soft tissue (12 cases), and others.	26379149
Inflammation, Periostitis, Vasculitis, CTCAE, Myositis, CTCAE 5.0	Altered Intercellular Communication	Myositis, periostitis, (peri-) vasculitis and axillary inflammation were confirmed by magnetic resonance imaging.	26379162
Inflammation, Pneumonitis	Altered Intercellular Communication	However, MAp2009-induced lung inflammation was sustained until the end of the study (day 14), while there was no sign of inflammation in the PR8-infected group by day 10.	26381265
Inflammation, Tumor necrosis	Altered Intercellular Communication	Additionally, inflammation is associated with M1-polarizated macrophages, which secrete cytokines such as tumor necrosis factor-a, interleukin-1, and interleukin-12, and present antigens through phagocytosis.	26382585
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	The glycoprotein YKL-40 is a new marker of early inflammation and endothelial dysfunction.	26382922
Stomach Carcinoma	Altered Intercellular Communication	It is involved in the regulation of inflammation-mediated carcinogenesis in human organs, including gastric cancer.	26383107
Inflammation	Altered Intercellular Communication	We diagnosed a broad, multiloculated mesenteric and retroperitoneal cyst, associated with intensive inflammation, in a 4-year-old girl.	26384119
Inflammation, Muscular Atrophy, Bipolar Disorder	Altered Intercellular Communication	Inflammation related to depressive symptoms may also contribute to muscle atrophy.	26384322
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Links between inflammation, amygdala reactivity, and social support in breast cancer survivors.	26384778
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	To date, however, little is known about the upstream neural processes that may link psychosocial stressors and inflammation in cancer patients and survivors.	26384778
Inflammation, Breast Carcinoma	Altered Intercellular Communication	These data suggest the possibility of a stronger "neural-immune pipeline" among breast cancer survivors, such that peripheral inflammation is more strongly associated with neural activity in threat-related brain regions.	26384778
Inflammation, Cardiac Death, Atherosclerosis	Altered Intercellular Communication	A case of sudden cardiac death due to eosinophilic coronary periarteritis: possible significance of coexisting atherosclerosis and eosinophilic inflammation of the esophagus.	26385173
Inflammation, Atherosclerosis	Altered Intercellular Communication	A short segment of the left anterior descending artery had ECPA with dense eosinophilic inflammation of the adventitia and mild atherosclerosis.	26385173
Inflammation	Altered Intercellular Communication	In addition, eosinophilic inflammation of the esophagus without mucosal involvement was present.	26385173
Inflammation	Altered Intercellular Communication	The eosinophilic inflammation of the coronary artery and esophagus was accompanied by an increased number of mast cells.	26385173
Inflammation, Atherosclerosis	Altered Intercellular Communication	This case suggests that ECPA and atherosclerosis may act synergistically by induction of inflammation and vasa vasorum neovascularization.	26385173
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	As low-grade inflammation predicts a poor outcome, the present study explored the potential associations between Type A and plasma levels of C-reactive protein (CRP) in diabetes.	26385557
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	This lower level of inflammation might explain the better clinical outcomes associated with Type A personality in patients with diabetes.	26385557
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Klotho Reduction in Alveolar Macrophages Contributes to Cigarette Smoke Extract-induced Inflammation in Chronic Obstructive Pulmonary Disease.	26385922
ARCN1 gene, Respiratory physiology, Abnormal inflammatory response, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Abnormal inflammation and accelerated decline in lung function occur in patients with chronic obstructive pulmonary disease (COPD).	26385922
ARCN1 gene, Inflammation	Altered Intercellular Communication	Our findings suggest that Klotho plays a role in sustained inflammation of the lungs, which in turn may have therapeutic implications in COPD.	26385922
Inflammation, Frailty, HIV Infections, Aspects of mortality statistics	Altered Intercellular Communication	Frailty, Inflammation, and Mortality Among Persons Aging With HIV Infection and Injection Drug Use.	26386010
Inflammation	Altered Intercellular Communication	Serum markers of inflammation increase with age and have been strongly associated with adverse clinical outcomes among both HIV-infected and uninfected adults.	26386010
Inflammation	Altered Intercellular Communication	Cytokines play important roles in the inflammation pathways.	26386715
Refractory anemias, Inflammation, Pain Distress Question	Altered Intercellular Communication	PA can improve physical function in RA, decrease chronic inflammation and reduce pain, without adversely affecting disease activity.	26386844
Inflammation, Edema, Myositis, CTCAE 5.0, Neoplasms	Altered Intercellular Communication	Knowledge of the imaging features of intramuscular migration of hydroxyapatite deposits is important in order to avoid the erroneous diagnosis of other causes of muscle edema and inflammation such as myotendinous injury, myositis, subacute denervation, and neoplasm.	26386846
Sepsis, Inflammation, Hypoxia, Septic Shock	Altered Intercellular Communication	Our data suggest a possible role for CXCL12 as a prognostic marker in severe sepsis/septic shock and give background evidence for larger trials to evaluate the pathophysiologic and clinical role of CXCL12 in sepsis, with respect to other markers of inflammation and hypoxia.	26387470
Inflammation, Central pain	Altered Intercellular Communication	Since the choroid plexus can mediate interaction between peripheral and brain inflammation, our findings pinpoint the choroid plexus as an important target for future research of central pain mechanisms.	26388497
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Coronary atherosclerosis in the young commonly shows an eccentric distribution with associated inflammation.	26390307
Inflammation, Pain Distress Question	Altered Intercellular Communication	The role of transient receptor potential vanilloid-1 (TRPV1) in the initiation of neurogenic inflammation and transduction of pain is well established.	26390894
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Betulinic acid inhibits IL-1b-induced inflammation by activating PPAR-g in human osteoarthritis chondrocytes.	26391061
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	In conclusion, these results suggested that BA inhibited IL-1b-induced inflammation in osteoarthritis chondrocytes by activating PPAR-g.	26391061
Synovitis, Inflammation, Hoarseness, Cartilage injury	Altered Intercellular Communication	However, some patients with hoarseness due to mucosal inflammation of the larynx might have accompanying synovitis and subsequent cartilage injury in the CA joint.	26391093
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Several cross-sectional, but few prospective, studies suggest that inflammation may be involved in the development of hypertension.	26391130
Inflammation, Atherosclerosis	Altered Intercellular Communication	High-sensitivity C-reactive protein (hsCRP), a marker of systemic inflammation, may promote atherosclerosis, particularly among adults with elevated blood pressure; however, data are sparse.	26391131
Inflammation, Neoplasms	Altered Intercellular Communication	Besides blocking inflammation, SOCS1 tumour suppressor activity involves Met receptor inhibition and enhancement of p53 tumour suppressor activity.	26391193
Refractory anemias, Rheumatoid Arthritis, destruction joint, Inflammation	Altered Intercellular Communication	Because MFG-E8 also controls bone metabolism, we investigated its role in rheumatoid arthritis (RA), focusing on inflammation and joint destruction.	26391522
Refractory anemias, Inflammation	Altered Intercellular Communication	The regulation of MFG-E8 by inflammation was assessed in vitro using osteoblasts, in arthritic mice and in patients with RA.	26391522
Inflammation, Liver carcinoma, Intrahepatic Cholangiocarcinoma, Malignant neoplasm of liver, FAM126A gene	Altered Intercellular Communication	Chronic inflammation plays a pivotal role in the pathogenesis of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC), the two most common types of liver cancer.	26391917
Autoimmune Diseases, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Th17 cells, a subset of IL-17-producing T cells distinct from Th1 or Th2 cells, have been described as key players in inflammation and autoimmune diseases as well as cancer development.	26392085
Inflammation, Immune System Diseases	Altered Intercellular Communication	Oxidative stress and chronic low-grade inflammation in the lungs are associated with aging and may contribute to age-related immune dysfunction.	26392224
Inflammation	Altered Intercellular Communication	To maintain lung homeostasis, chronic inflammation is countered by enhanced expression of proresolving/antiinflammatory factors.	26392224
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Inflammation, Depression, and Slow Gait: A High Mortality Phenotype in Later Life.	26392405
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Inflammation, slow gait, and depression individually are associated with mortality, yet little is known about the trajectories of these measures, their interrelationships, or their collective impact on mortality.	26392405
Inflammation, Impaired health, Depression, CTCAE	Altered Intercellular Communication	For each outcome, low-probability (n inflammation = 1,656, n slow gait = 1,471, n depression = 1,458), increasing-probability (n inflammation = 847, n slow gait = 880, n depression = 1,062), and consistently high-probability (n inflammation = 572, n slow gait = 724, n depression = 555) trajectories were identified, with 22% of all participants classified as having increasing or consistently high-probability trajectories on inflammation, slow gait, and depression (meaning probability of impairment on each outcome increased from low to moderate/high or remained high over 10 years).	26392405
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Trajectories of slow gait were associated with inflammation (r = .40, p < .001) and depression (r = .49, p < .001).	26392405
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Although worsening trajectories of inflammation were independently associated with mortality (p < .001), the association between worsening trajectories of slow gait and mortality was only present in participants with worsening depression trajectories (p < .01).	26392405
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Participants with increasing/consistently high trajectories of depression and consistently high trajectories of inflammation and slow gait (n = 247) have an adjusted-morality rate of 85.2%, greater than all other classification permutations.	26392405
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Comprehensive assessment of older adults is warranted for the development of treatment strategies targeting a high-mortality risk phenotype consisting of inflammation, depression, and slow gait speed.	26392405
Inflammation, Chronic Obstructive Airway Disease, Impairment of balance	Altered Intercellular Communication	Balance impairment and systemic inflammation in chronic obstructive pulmonary disease.	26392759
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Impairment of balance	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD), especially in severe forms, is commonly associated with systemic inflammation and balance impairment.	26392759
ARCN1 gene, Inflammation, Lower Extremity Paresis, Impairment of balance	Altered Intercellular Communication	According to this study, COPD in advanced and acute stages is associated with an increased history of falls, systemic inflammation, balance impairment, and lower extremity muscle weakness.	26392759
Data types - Address	Altered Intercellular Communication	Inflammation would induce autophagy in the PBMCs of AD patients while an anti-inflammatory environment could inhibit their autophagic response.	26393801
Inflammation, GTF2A1L wt Allele, Bacterial Infections	Altered Intercellular Communication	While PCT appears to be a robust assay for detecting bacterial infection in the general population, there was poor discrimination between ALF patients with or without bacterial infection presumably because of the massive inflammation observed.	26393924
Inflammation, GTF2A1L wt Allele, Necrosis	Altered Intercellular Communication	Severe hepatocyte necrosis with inflammation results in elevated PCT levels, rendering this biomarker unreliable in the ALF setting.	26393924
Inflammation, Actual blood loss, Anemia, Kidney Failure	Altered Intercellular Communication	Several mechanisms have been implicated in the etiology of anemia in this setting, including inflammation, blood loss, and the presence of comorbidities such as renal failure.	26394493
Inflammation, Erythema, Fissure	Altered Intercellular Communication	We developed an Isotretinoin Cheilitis Grading Scale (ICGS) incorporating the following four characteristics: erythema, scale/crust, fissures and inflammation of the commissures.	26395167
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	It is more predominant in patients with Chronic Kidney Disease in comparison to healthy subjects, which can also be diagnosed in non-elderly individuals and be associated with innumerous causes such as muscle strength, body composition and inflammation.	26395776
Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	Processes unrelated to kidney function such as acute inflammation have a significant effect on post-CPB changes in these biomarkers, and may result in significant increases in serum cystatin C that could erroneously be interpreted as AKI.	26396066
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	While sequestration of parasitized erythrocytes is thought to be critical, the roles of inflammation and coagulation are controversial.	26396242
Inflammation, HIV Infections, Certified Midwife	Altered Intercellular Communication	Because HIV infection is associated with dysregulated inflammation and platelet activation, we performed immunohistochemistry analysis for monocytes, platelets, and neutrophils in brain tissue from HIV(+) and HIV-uninfected children with fatal CM.	26396242
Inflammation, Observation Method - Coagulation, Certified Midwife	Altered Intercellular Communication	Brain histopathology supports the hypotheses that inflammation and coagulation contribute to the pathogenesis of pediatric CM and that immune dysregulation in HIV(+) children exacerbates the pathological features associated with CM.	26396242
Inflammation, Malaria, Observation Method - Coagulation, Certified Midwife	Altered Intercellular Communication	Our findings raise the possibility that HIV(+) children at risk for malaria may benefit from targeted malaria prophylaxis and that adjunctive treatments targeting inflammation and/or coagulation may improve CM outcomes.	26396242
Hypercholesterolemia, Inflammation	Altered Intercellular Communication	We aimed to elucidate the underlying mechanism of NR4A1 expression in monocytes during hypercholesterolaemia, and reveal the potential role of NR4A1 in hypercholesterolaemia-induced circulating inflammation.	26396259
Hypercholesterolemia, Inflammation	Altered Intercellular Communication	Thus we conclude that histone acetylation contributes to the regulation of NR4A1 expression in hypercholesterolaemia, and that NR4A1 expression reduces hypercholesterolaemia-induced inflammation.	26396259
Inflammation, Metabolic Diseases	Altered Intercellular Communication	Our results demonstrate a higher circulating ANGPTL2 level in patients with HF, and the upregulating ANGPTL2 levels might be associated with metabolic derangements and inflammation.	26397985
Granulomatous inflammation, Crohn Disease	Altered Intercellular Communication	Granulomatous inflammation consistent with Crohn's disease was found on histopathological examination.	26398073
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation, Endothelial Dysfunction and Increased Left Ventricular Mass in Chronic Kidney Disease (CKD) Patients: A Longitudinal Study.	26398099
Inflammation, Endothelial dysfunction, Chronic Kidney Diseases	Altered Intercellular Communication	The results suggest that in predialysis CKD patients, inflammation as well as endothelial dysfunction may play an important role towards the increase in LVMI.	26398099
Inflammation, Coronary Artery Disease, Bipolar Disorder	Altered Intercellular Communication	It is well known that inflammation contributes to the development of coronary artery disease (CAD) and depressive symptoms.	26398164
Inflammation, Depression, CTCAE, Bipolar Disorder	Altered Intercellular Communication	We hypothesized that inflammation contributes to depression in patients with CAD and statin function as an anti-inflammation therapy for those depressive patients.	26398164
Inflammation, Depression, CTCAE	Altered Intercellular Communication	It suggested that depression in patients with CAD is associated with inflammation.	26398164
Depression, CTCAE	Altered Intercellular Communication	Statin may function as an anti-inflammation therapy for depression in patients with CAD by downregulation of IL-1b.	26398164
Inflammation, Coronary heart disease, Atrial Fibrillation by ECG Finding, Cerebrovascular accident	Altered Intercellular Communication	Inflammation and hemostasis in atrial fibrillation and coronary heart disease: The REasons for Geographic And Racial Differences in Stroke study.	26398291
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	To determine if alterations in hemostasis or inflammation explain the association between AF and CHD.	26398291
Inflammation, Atrial Fibrillation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Using a case-cohort approach, Cox models examined whether inflammation or hemostasis biomarkers explained the association between AF and CHD.	26398291
Inflammation, Pouchitis, Crohn Disease	Altered Intercellular Communication	Sixty-one percent of respondents had pouch inflammation (pouchitis, N = 35; cuffitis, N = 14; and Crohn's disease of the pouch, N = 35), 20% had IPS (N = 27) and 19% (N = 26) had asymptomatic normal pouches.	26398708
Inflammation, Malnutrition, Crohn Disease	Altered Intercellular Communication	Systemic inflammation and nutritional deficiencies are characteristics of Crohn's disease (CD) and have been suggested to influence cognitive performance.	26398711
Airway structure, Asthma	Altered Intercellular Communication	These results suggest that airway inflammation aggravated by ADS exposure may induce a decrease in pulmonary function in some adult patients with asthma.	26399354
Inflammation	Altered Intercellular Communication	Increased serum levels of CRP and serum and aqueous levels of TNF-a in DME suggest that inflammation is involved in the pathogenesis of DME.	26400051
Neurodegenerative Disorders, Primary malignant neoplasm, Inflammation, Autoimmune Diseases, Diabetes Mellitus	Altered Intercellular Communication	Chronic inflammation negatively impacts all physiological functions, causing an array of degenerative conditions including diabetes; cancer; cardiovascular, osteo-articular, and neurodegenerative diseases; autoimmunity disorders; and aging.	26400428
Inflammation	Altered Intercellular Communication	We attempted relief of symptoms by reducing scalp inflammation and eliminating hair follicles through radiation.	26400479
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	The pro-inflammatory cytokine IL-17, which is produced by T-helper 17 (Th17) cells, has been reported to be involved in the glucose metabolism and pathogenesis of diabetes via the induction of low-grade inflammation.	26400516
Inflammation, Squamous cell carcinoma of esophagus	Altered Intercellular Communication	Diet and inflammation have been suggested to be important risk factors for esophageal squamous cell carcinoma (ESCC).	26400625
Inflammation	Altered Intercellular Communication	Similarly, vocal fold injection of silicone elastomer (Silastic) can result not only in a false-positive FDG uptake on PET/CT, but also in chronic inflammation.	26401671
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Peripheral inflammation has been suggested to influence the development of Alzheimer's disease (AD).	26402013
Inflammation, atherosclerotic	Altered Intercellular Communication	Based on our in vivo and in vitro findings we suggest that NAMPT could contribute to systemic and plaque inflammation in atherosclerotic disorders at least partly through effect on macrophages.	26402139
Inflammation, Data types - Address	Altered Intercellular Communication	Inflammation is involved in AD and it is suggested that anti-inflammatory interleukin-10 (IL-10) may partly antagonize these processes.	26402514
Inflammation, Vasogenic Edema	Altered Intercellular Communication	Neuroradiological evidence of cerebral inflammation (vasogenic edema) and sulcal superficial siderosis or multiple areas of cortical/subcortical microhemorrhages (MHs) were evaluated based upon fluid-attenuated inversion recovery and T2 *-weighted gradient echo or susceptibility weighted imaging, respectively.	26402633
HIV Infections	Altered Intercellular Communication	We thus identified adipose tissue as a crucial cofactor in both viral persistence and chronic immune activation/inflammation during HIV infection.	26402858
Inflammation	Altered Intercellular Communication	These observations open up new therapeutic strategies for limiting the size of the viral reservoir and decreasing low-grade chronic inflammation via the modulation of adipose tissue-related pathways.	26402858
Inflammation	Altered Intercellular Communication	Collectively, results indicated that elevated serum FLCs reflects increased B cell activity in relation to inflammation.	26402865
Inflammation, Hematoma, Cerebral Hemorrhage	Altered Intercellular Communication	CD163/Hemoglobin Oxygenase-1 Pathway Regulates Inflammation in Hematoma Surrounding Tissues after Intracerebral Hemorrhage.	26403367
Inflammation, Hematoma, Hemorrhage	Altered Intercellular Communication	The highest inflammation level in tissues surrounding ICH hematomas occurred 2-3 days after bleeding onset, but was accompanied by an anti-inflammatory factor IL-10 expression enhancement.	26403367
Inflammation, Glucose Intolerance (disease), Obesity, Hyperlipidemia	Altered Intercellular Communication	Epidemiological evidence indicates an inverse association between nut consumption and obesity, inflammation, hyperlipidaemia and glucose intolerance.	26404365
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is characterized by chronic synovial inflammation due to unknown causes.	26404390
Inflammation, Traumatic injury, Pruritus, Pain Distress Question	Altered Intercellular Communication	Keloids may follow local skin trauma or inflammation leading to pruritus, pain, restriction of movement or cosmetic disfigurement.	26404425
Inflammation	Altered Intercellular Communication	The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4.	26404840
Inflammation	Altered Intercellular Communication	GATA4 accumulates in multiple tissues, including the aging brain, and could contribute to aging and its associated inflammation.	26404840
Upper Respiratory Infections, Congenital Abnormality, Communicable Diseases, Respiration Disorders, Lung diseases	Altered Intercellular Communication	We examined associations between FOT outcomes and the presence and progression of respiratory inflammation, infection and structural lung disease.Children with CF who had pronounced respiratory disease, including free neutrophil elastase activity, infection with pro-inflammatory pathogens and structural lung abnormalities had similar FOT outcomes to those children without detectable lung disease.	26405283
Inflammation, Chronic Kidney Diseases, Glomerulonephritis, Toxic nephropathy	Altered Intercellular Communication	Their increased risk of CKD may be attributed to glomerulonephritis, chronic inflammation, comorbidities, and renal toxicity of antirheumatic drugs.	26406879
Inflammation, Uveitis	Altered Intercellular Communication	Uveitis was classified based on the anatomic location of inflammation (IUSG classification).	26408195
Inflammation, Panuveitis, Scleritis, Uveitis, Retinal Vasculitis, Traumatic injury, Anterior uveitis, Endophthalmitis, CTCAE	Altered Intercellular Communication	Out of 980 patients with uveitis, 413 (42.14 %) patients had anterior uveitis, 131 (13.36 %) had intermediate uveitis, 165 (16.83 %) had posterior uveitis, 91 (9.2 %) had panuveitis, 47 (4.7 %) had retinal vasculitis, 22 (2.24 %) had scleritis, 17 (1.7 %) had masquerade syndromes, 8 (0.8 %) had keratouveitis, 22 (2.24 %) had sclerokeratouveitis, 19 (1.9 %) had endophthalmitis and 45 (4.5 %) had other causes of inflammation including trauma and intraocular surgery.	26408195
Inflammation	Altered Intercellular Communication	Receptor binding leads to activation of the vascular endothelium and increased inflammation in the vessel wall.	26408307
Arterial Stiffness, Inflammation, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8	Altered Intercellular Communication	The results show a possible protective effect of high levels of sRAGE at baseline against inflammation 5 years later, but not on arterial stiffness or wall thickness, in this cohort of adolescents and young adults with T1D.	26408307
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Nerve growth factor and its receptors, TrkA and p75NTR, are involved in inflammation and airways diseases, but their role in chronic obstructive pulmonary disease is still unclear and not well investigated.	26408608
Inflammation, Anemia	Altered Intercellular Communication	Fifty-four could not be classified: 12 were anaemic with findings, other than normal CRP values, indistinguishable from those with anaemia of inflammation and 42 were non-anaemic with reduced MCH values.	26408651
Dermatitis, Atopic, Data types - Address	Altered Intercellular Communication	Atopic dermatitis (AD) is defined as a chronic, highly pruritic inflammatory condition of skin.	26408885
Trismus, Inflammation	Altered Intercellular Communication	Clinical examination revealed palpable crepitus at the level of the head, neck and pre-sternal region but no inflammation, trismus or fluid collection was detected.	26409565
Inflammation, Angioedemas, Hereditary	Altered Intercellular Communication	C1 inhibitors are approved for hereditary angioedema but may show promise in alleviating inflammation associated with ACE inhibitor angioedema.	26409672
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	FLS via eotaxin-1 and its receptor CCR3 plays an important role in the pathogenesis of OA, which strengthen the concept that OA is likely an inflammation related disease.	26409848
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Increasing evidence suggests that inflammation plays an important role in initiation and maintaining of atrial fibrillation (AF).	26411136
Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	A strong interdependence is known between atrial fibrillation (AF), inflammation and thrombogenesis.	26411420
Inflammation, Fatty degeneration, Cachexia, Pancreatic carcinoma	Altered Intercellular Communication	Patients with pancreatic cancer have a poor prognosis, are often cachectic, and frequently demonstrate features of systemic inflammation, which may contribute to the phenomenon of myosteatosis.	26411749
Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Atrial fibrillation is associated with hematopoietic tissue activation and arterial inflammation.	26411879
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation is associated with the development of atrial fibrillation (AF).	26411879
Inflammation, Arteritis	Altered Intercellular Communication	Activity in hematopoietic tissues, which produce inflammatory leukocytes, is closely related to systemic inflammation, arterial inflammation and cardiovascular events, but its relationship to AF is unknown.	26411879
vascular inflammations	Altered Intercellular Communication	Using 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) imaging, we examined the relationships between AF, splenic metabolic activity and vascular inflammation.	26411879
Vasculitis	Altered Intercellular Communication	Splenic metabolic activity and vascular aortic inflammation were measured by the mean FDG maximum standard uptake values (SUV Max) by PET.	26411879
Inflammation	Altered Intercellular Communication	Aortic inflammation was also higher in AF participants [2.22 (SD 0.44) vs. 1.91 (SD 0.44), p = 0.004], and remained significant on multivariable analysis.	26411879
Inflammation	Altered Intercellular Communication	Aortic inflammation and splenic activity were highly correlated (Pearson R = 0.61, p < 0.001).	26411879
Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Atrial fibrillation is associated with higher hematopoietic tissue activation and arterial inflammation.	26411879
Inflammation, Endothelial dysfunction, Vascular Alterations	Altered Intercellular Communication	They are caused by cardiovascular risk factors including low-grade inflammation process, endothelial dysfunction, oxidative stress, and hemodynamic and vascular alterations.	26412411
Inflammation, Nasal Polyps, Sinusitis	Altered Intercellular Communication	To analyze the differential expression of miRNAs in chronic sinusitis, with or without nasal polyps (nasal polyps, NP), seven miRNAs (miR- 181b, miR-26b, miR-155, miR-146a, miR-125b, miR-124 and miR-92a) that are associated with inflammation were selected to be quantifying by RT-qPCR in 40 clinical samples and 5 controls.	26413631
Inflammation, Craniosynostosis	Altered Intercellular Communication	The RT-qPCR results indicate that the miRNAs were differentially expressed in CRS patients and various inflammation severities could lead to this difference.	26413631
Inflammation	Altered Intercellular Communication	Chronic inflammation and risk of colorectal and other obesity-related cancers: The health, aging and body composition study.	26413860
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Evidence of the association between chronic inflammation and the risk of colorectal cancer (CRC) and other obesity-related cancers (OBRC) remains inconsistent, possibly due to a paucity of studies examining repeated measures of inflammation.	26413860
Inflammation, Atherosclerosis	Altered Intercellular Communication	The relationship between inflammation and neoangiogenesis of epicardial adipose tissue and coronary atherosclerosis based on computed tomography analysis.	26414208
Inflammation, Atherosclerosis	Altered Intercellular Communication	We evaluated the relationship between EAT pathology, represented by inflammation and neoangiogenesis, and coronary atherosclerosis on computed tomography (CT) images.	26414208
Inflammation, Calcification of coronary artery, Coronary Arteriosclerosis, Eating	Altered Intercellular Communication	Inflammation and neoangiogenesis in EAT independently correlate with moderate coronary calcification and presence of NCP, suggesting that these two factors may have a role in promoting coronary atherosclerosis.	26414208
Degenerative polyarthritis, Inflammation, Superficial ulcer	Altered Intercellular Communication	Brief Report: Association of Inflammation With Development of Erosions in Patients With Hand Osteoarthritis: A Prospective Ultrasonography Study.	26414489
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	To investigate the association between features of ultrasound-detected inflammation and development of erosive disease in patients with hand osteoarthritis (OA) over 2.3 years of followup.	26414489
Inflammation, Superficial ulcer	Altered Intercellular Communication	Persistent inflammation was particularly associated with the development of erosions.	26414489
Degenerative polyarthritis, Inflammation, Superficial ulcer	Altered Intercellular Communication	Ultrasound-detected features of inflammation are associated with the development of erosions in patients with hand OA, suggesting that inflammation plays a role in the pathogenesis of hand OA and could be a therapeutic target.	26414489
Inflammation, Tumor necrosis, HIV Infections	Altered Intercellular Communication	Chronic inflammation marked by elevated interleukin (IL)-6, soluble tumor necrosis factor (TNF)-a receptor (sTNFR)-1, and sTNFR-2 levels may play a detrimental role in aging and HIV infection.	26414536
Inflammation, HIV Infections	Altered Intercellular Communication	These findings provide initial insight into the in vivo relationship between TNF-a activation and IL-6 and a basis for further investigations into potential mechanisms underlying chronic inflammation in aging and HIV infection.	26414536
Inflammation	Altered Intercellular Communication	When acting as allergens to induce type I responses, microscopic agents other than parasites in the intestinal tract could induce eosinophilic inflammation in the liver.	26414822
Inflammation, Brain Injury, Chronic, Fibrosis Assessment	Altered Intercellular Communication	It protects kidney against acute and chronic injury, inflammation and fibrosis.	26415312
Inflammation	Altered Intercellular Communication	A 71-year-old man was referred to our department due to inflammation in the right scrotum.	26415366
Inflammation, Inflammatory dermatosis	Altered Intercellular Communication	AA patients have a higher incidence of various T-cell-driven inflammatory skin diseases than the normal population, a phenomenon which might relate to over-activation of skin-homing T cells and to specific immune triggers as the primary cause of inflammation.	26416203
Inflammation	Altered Intercellular Communication	The results indicate that terrein has an alleviative function of age-related inflammation characterized as an anti-oxidant.	26416516
Cerebral Small Vessel Diseases, Inflammation	Altered Intercellular Communication	Perivascular spaces (PVS) are associated with ageing, cerebral small vessel disease, inflammation and increased blood brain barrier permeability.	26416614
Canaliculitis, Inflammation, Lacrimation	Altered Intercellular Communication	Among the 14 patients, lacrimal punctal granuloma formation occurred in 3 patients, tearing occurred in 6 patients, canaliculitis occurred in 3 patients, and chronic inflammation of the ocular surface occurred in 2 patients.	26418430
Inflammation	Altered Intercellular Communication	During wound healing after surgery, physiological inflammation leads to an increase in soft tissue perfusion.	26419379
Inflammation, Neurogenic Inflammation, Cirrhotic, Liver Failure	Altered Intercellular Communication	The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients.	26420028
Inflammation, Cirrhotic	Altered Intercellular Communication	Levels of several pro-inflammatory cytokines and those of NO/cGMP homeostasis metabolites were measured in PCS rats and cirrhotic patients to conclude on the role of PREP in inflammation.	26420028
Inflammation	Altered Intercellular Communication	Low haemoglobin levels contribute to low grip strength independent of low-grade inflammation in Japanese elderly women.	26420185
Inflammation, Carcinogenesis, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Chronic inflammation of gastric mucosa by Helicobacter pylori infection can initiate gastric carcinogenesis.	26420253
Inflammation, Carcinogenesis, Stomach Carcinoma	Altered Intercellular Communication	As angiopoietin-like protein 2 (ANGPTL2) mediates inflammation and inflammation-associated carcinogenesis, we investigated the functional and clinical significance of ANGPTL2 in human gastric cancer (GC).	26420253
Inflammation, Diabetic Retinopathy, GDC Disease Response Terminology	Altered Intercellular Communication	Inflammation is one important mechanism of diabetic retinopathy (DR).	26420914
Inflammation, Disorder characterized by fever	Altered Intercellular Communication	Inflammation can occur during the febrile illness or months later and can manifest in a variety of ways.	26421893
Chikungunya Fever, Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	Given the wide variety of presentations, chikungunya fever-related uveitis should be included in the differential diagnosis of all at-risk patients presenting with acute ocular inflammation, particularly those traveling from endemic regions.	26421893
Inflammation, Primary malignant neoplasm, Atrophic	Altered Intercellular Communication	Prevalences of cancer, HGPIN, atrophy, or inflammation posttreatment were similar; however, more extensive atrophy and less extensive HGPIN was more common in the lycopene group.	26422197
Inflammation, HIV Antigens	Altered Intercellular Communication	Whether the reported high risk of age-related diseases in HIV-infected people is caused by biological ageing or HIV-associated risk factors such as chronic immune activation and low-grade inflammation is unknown.	26423253
Inflammation, Squamous cell carcinoma of esophagus	Altered Intercellular Communication	The clinical significance of systemic inflammation score in esophageal squamous cell carcinoma.	26423404
Squamous cell carcinoma of esophagus	Altered Intercellular Communication	SIS was a novel and promising inflammation-based prognostic score than PNI in ESCC patients who underwent esophagectomy.	26423404
Inflammation, Folliculitis	Altered Intercellular Communication	The widespread dermis inflammation was more frequent in severe EPPEs and in patients treated with cetuximab, while the hair follicle inflammation was observed only in mild/moderate EPPEs.	26423594
Granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	Therefore, we proceeded with laparoscopy which showed multiple nodular deposits on abdominal wall, bowel and omentum and peritoneal biopsy revealed granulomatous inflammation with caseous type necrosis compatible with mycobacterium tuberculosis infection.	26423615
Inflammation, Portal Vein Thrombosis, Tuberculosis	Altered Intercellular Communication	This was confirmed by tuberculosis genome identification on the biopsy sample confirming a diagnosis of peritoneal tuberculosis with secondary portal vein thrombosis and cavernous formation due to local inflammation.	26423615
Hepatic inflammation	Altered Intercellular Communication	Serum levels of hepatic inflammation enzymes along with fatty liver changes were significantly elevated by DEP exposure.	26423653
Inflammation, Dental Plaque, Ischemic stroke, Atherosclerosis	Altered Intercellular Communication	Cytochrome P450s (CYP450) enzymes regulate inflammation and atherosclerosis and can affect carotid plaque stability in patients with ischemic stroke (IS).	26423716
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic Obstructive Pulmonary Disease (COPD) is characterized by lung and systemic inflammation as well as airway goblet cell hyperplasia (GCH).	26424214
Inflammation, Peri-Implantitis	Altered Intercellular Communication	The present data suggest that the increased levels of the selected PICF-derived biomarkers of periodontal tissue inflammation, matrix degradation/regulation, and alveolar bone turnover/resorption combined with site-specific microbial profiles may be associated with peri-implantitis and could have potential as predictors of peri-implant diseases.	26424287
Inflammation, Non-Small Cell Lung Carcinoma, Malignant Neoplasms	Altered Intercellular Communication	The immunological status, consisting of "inflammation status" and "nutritional condition," is important for the survival of patients with various cancers, including non-small cell lung cancer (NSCLC).	26424708
Inflammatory Bowel Diseases, Anxiety, CTCAE 3.0, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Mind-body interventions, such as BBMW, which emphasize Voluntarily Regulated Breathing Practices, may have significant long-lasting benefits for IBD symptoms, anxiety, depression, quality of life, and inflammation.	26426148
Retinal Detachment, Oculovestibuloauditory syndrome, Choroiditis	Altered Intercellular Communication	This is the first known case of a serous neurosensory retinal detachment from suspected choroidal inflammation associated with Cogan syndrome.	26426408
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Among seven patients undergoing colonoscopy because of a suspicion of inflammatory bowel disease, five were free of pathological signs and two patients with pathological endoscopy findings had nonspecific inflammation as documented by histopathological examination.	26426964
Inflammation, Nephrogenic metaplasia	Altered Intercellular Communication	Nephrogenic adenoma, also referred to nephrogenic metaplasia, is a benign proliferative lesion of urothelium, usually associated with chronic physical stimuli or inflammation.	26428868
Inflammation, Vesico-Ureteral Reflux, Nephrogenic metaplasia	Altered Intercellular Communication	There is a possibility that control of inflammation caused by the surgery for vesicoureteral reflux in the local site didn't work well on the background of heterozygous mutation of MEFV gene, and as a result, nephrogenic adenoma appeared.	26428868
Inflammation	Altered Intercellular Communication	Regulation of HBV-specific CD8(+) T cell-mediated inflammation is diversified in different clinical presentations of HBV infection.	26428923
Malignant neoplasm of liver, Acute and chronic inflammation, Liver Cirrhosis	Altered Intercellular Communication	Chronic HBV infection is the leading cause of liver cirrhosis and hepatic cancer, but the individual responses toward HBV infection are highly variable, ranging from asymptomatic to chronic active hepatitis B inflammation.	26428923
Inflammation	Altered Intercellular Communication	In this study, we hypothesized that the different individual responses to HBV infection was associated with differences in HBV-specific CD8(+) T cell-mediated inflammation and cytotoxicity.	26428923
Inflammation, Molluscum Contagiosum	Altered Intercellular Communication	The microscopic examination revealed bud-like proliferation of the epidermis, molluscum bodies and moderate chronic inflammation of the dermis.	26429183
Inflammation, Smoking	Altered Intercellular Communication	Smoking is a well-known risk factor for inflammation.	26429291
Inflammation, HIV	Altered Intercellular Communication	Low zinc levels and chronic inflammation are common in individuals infected with human immunodeficiency virus (HIV).	26429417
Inflammation	Altered Intercellular Communication	Zinc deficiency may promote systemic inflammation, but research on the role of zinc in inflammation among HIV-positive individuals taking account of anti-retroviral therapy is lacking.	26429417
Degenerative polyarthritis	Altered Intercellular Communication	These include intra-articular structures (degenerative arthritis, and inflammatory conditions) as well as extra-articular structures (ligaments, muscles, etc.	26431131
Fever, CTCAE	Altered Intercellular Communication	Fever appeared to be aggravated by acetaminophen and more related to the elevation of hepatic enzymes than to the change in the inflammation-related cytokines.	26431202
Parkinson Disease, Inflammation, RNA Recognition Motif	Altered Intercellular Communication	Investigation on Abnormal Iron Metabolism and Related Inflammation in Parkinson Disease Patients with Probable RBD.	26431210
Parkinson Disease, Inflammation, palladium, REM Sleep Behavior Disorder	Altered Intercellular Communication	To investigate potential mechanisms involving abnormal iron metabolism and related inflammation in Parkinson disease (PD) patients with probable rapid eye movement sleep behavior disorder (PRBD).	26431210
Inflammation, Chronic Kidney Diseases, Metabolic Syndrome X	Altered Intercellular Communication	Chronic Kidney Disease in Non-Diabetic Older Adults: Associated Roles of the Metabolic Syndrome, Inflammation, and Insulin Resistance.	26431218
Inflammation, Metabolic Syndrome X, Chronic Kidney Diseases	Altered Intercellular Communication	We also explored two possible pathways linking the metabolic syndrome with CKD: inflammation as measured by high sensitivity C-Reactive Protein (hsCRP) and insulin resistance as measured by HOMA-IR.	26431218
Dyslipidemias, Metabolic Syndrome X	Altered Intercellular Communication	A Larger Body Mass Index is Associated with Increased Atherogenic Dyslipidemia, Insulin Resistance, and Low-Grade Inflammation in Individuals with Metabolic Syndrome.	26431271
ARCN1 gene, Inflammation, Hypoxia	Altered Intercellular Communication	Our study indicated that serum IMA, ox-LDL, and TOS may be increased as a result of chronic hypoxia, inflammation, and oxidative stress in patients with severe and very severe stable COPD.	26431591
Pain Distress Question, Peritoneal Diseases, Tenosynovitis	Altered Intercellular Communication	Peroneal tendon disorders, including the tendon sheath inflammatory condition tenosynovitis, are a major cause of chronic lateral ankle pain.	26432083
Inflammation, Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	Inflammation can promote tumor growth, invasion, angiogenesis and even metastasis.	26432433
Inflammation, Damage, Demyelination	Altered Intercellular Communication	Secondary outcomes were other CSF biomarkers of inflammation, axonal damage and demyelination; clinical scores; magnetic resonance imaging measures of disease activity, magnetization transfer ratio (MTR) and diffusion tensor imaging (DTI); motor evoked potentials; and bone density scans.	26432857
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Inflammation plays a central role in the pathogenesis of chronic rhinosinusitis (CRS), and TNFa is a key pro-inflammatory cytokine in the pathogenesis of this disease.	26433033
Inflammation	Altered Intercellular Communication	SCC/MCC is aggressive, arising within elderly patients' chronically ultraviolet-exposed skin, often in the setting of immunosuppression or inflammation.	26433246
Inflammation, CHOP regimen, Arthritis, Psoriatic	Altered Intercellular Communication	Effect of tight control of inflammation in early psoriatic arthritis (TICOPA): a UK multicentre, open-label, randomised controlled trial.	26433318
Inflammation, Rheumatoid Arthritis, Arthritis, Psoriatic	Altered Intercellular Communication	Early intervention and tight control of inflammation optimise outcomes in rheumatoid arthritis but these approaches have not yet been studied in psoriatic arthritis.	26433318
Airway structure, Asthma, Atopy	Altered Intercellular Communication	Meanwhile, fractional exhaled nitric oxide (FeNO) concentration, used in assessing airway inflammation in bronchial asthma, is known to be affected by atopic disposition.	26433532
Hyperplasia, Arteritis	Altered Intercellular Communication	These failures are primarily due to the development of neointimal hyperplasia, resulting from arterial wall inflammation.	26433546
Inflammation, Depression, CTCAE, Endothelial dysfunction	Altered Intercellular Communication	Association of Type D personality with increased vulnerability to depression: Is there a role for inflammation or endothelial dysfunction?	26433759
Inflammation, Depression, CTCAE, Endothelial dysfunction	Altered Intercellular Communication	We examined whether (1) Type D is a vulnerability factor for depression in general, (2) Type D is associated with inflammation or endothelial dysfunction, and (3) these biomarkers alter the possible association between Type D and depression.	26433759
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Multivariable regression analyses showed that Type D was associated with inflammation (b=0.228, p=0.014) and endothelial dysfunction (b=0.216, p=0.022).	26433759
Inflammation, Depression, CTCAE, Endothelial dysfunction	Altered Intercellular Communication	Type D personality may be a vulnerability factor for depression, irrespective of levels of inflammation or endothelial dysfunction.	26433759
Dyspnea, Inflammation	Altered Intercellular Communication	This study set out to examine the relative importance of potential contributors to dyspnea, ie, disease severity, inflammation and psychologic distress in a large prospective cohort of chronic HF patients.	26435096
ARCN1 gene, Inflammation, Anxiety, CTCAE 3.0, Chronic Obstructive Airway Disease, Depression, CTCAE, Dyspnea	Altered Intercellular Communication	Linear mixed modeling analysis with maximum likelihood estimation showed that when determinant clusters were entered separately, comorbid chronic obstructive pulmonary disease (COPD) was significantly associated with dyspnea complaints (P = .039), as were depression (P < .001) and anxiety (P < .001), whereas inflammation did not significantly affect dyspnea complaints.	26435096
Inflammation, Medically Unexplained Symptoms, hafnium, Dyspnea, Overweight	Altered Intercellular Communication	The experience and report of dyspnea in HF is determined foremost by somatic symptoms of psychologic distress, being of older age, being overweight, and having comorbid COPD, with disease severity and systemic inflammation levels playing an ancillary role.	26435096
Inflammation	Altered Intercellular Communication	Interleukin- (IL-) 37 is a novel anti-inflammatory cytokine that suppresses immune response and inflammation.	26435567
glycation, Inflammation	Altered Intercellular Communication	The S100 family and receptor for advanced glycation end products (RAGE) participate in regulating inflammation, even in the production of matrix metalloproteinases (MMPs).	26436377
Inflammation, Hyperkeratosis	Altered Intercellular Communication	No subungual debris, hyperkeratosis, or paronychial inflammation was present in the affected nail.	26437286
Inflammation, Chronic lung disease	Altered Intercellular Communication	It has gained interest as a biological marker in chronic lung diseases because of its presumed relationship to inflammation.	26439880
Inflammation	Altered Intercellular Communication	PRX5 elevation in MG could be related to the neuromuscular junction breakdown and plays a pivotal role in the pathogenic inflammation of MG.	26439955
T-Lymphocyte, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic	Altered Intercellular Communication	T lymphocyte hyperactivity and progressive inflammation in systemic lupus erythematosus (SLE) patients results in over-expression of human leucocyte antigen (HLA)-Ib on the surface of lymphocytes.	26440212
Inflammation	Altered Intercellular Communication	These are shed into the circulation upon inflammation, and may augment production of antibodies promoting pathogenicity of the disease.	26440212
Inflammation, Stanford Cancer Institute, Immune System Diseases, Infection	Altered Intercellular Communication	These data support additional functional studies of T cells isolated from individuals with chronic SCI, where alterations in T cell homeostasis may contribute to immune dysfunction, such as immunity against infections or the persistence of chronic inflammation.	26440591
Inflammation, Coronary microvascular dysfunction, Coronary Artery Disease, CAMPOMELIC DYSPLASIA, Chronic inflammatory disorder	Altered Intercellular Communication	Chronic inflammatory disease (CID) is a complex multisystem disease characterized by chronic inflammation, which can lead to coronary microvascular dysfunction (CMD) and can also predispose to coronary artery calcium deposition, even in the absence of obstructive coronary artery disease.	26443046
Airway structure	Altered Intercellular Communication	Fractional exhaled nitric oxide (FeNO) is a noninvasive biomarker of eosinophilic airway inflammation.	26443435
Prediabetes syndrome, Erectile dysfunction	Altered Intercellular Communication	Hormonal determinants of erectile dysfunction and lower urinary tract symptoms in middle-aged and elderly men with prediabetes.	26444448
Inflammation, Neoplasms	Altered Intercellular Communication	Inflammation is a critical component of tumor progression.	26444485
Stomach Carcinoma	Altered Intercellular Communication	It has been widely accepted that gastric cancer is an inflammation-driven cancer.	26444485
Inflammation, physiopathological	Altered Intercellular Communication	Potentially, the increase of SBPV will aggravate venous wall inflammation and may play a role in AVF dysfunction.	26444591
Inflammation, Lower Urinary Tract Symptoms, Depression, CTCAE	Altered Intercellular Communication	Inflammation has recently been identified as an independent risk factor for LUTS and depression.	26445118
Anxiety, CTCAE 3.0, Inflammation, Lower Urinary Tract Symptoms, Depression, CTCAE	Altered Intercellular Communication	This study aimed to assess the association between depression, anxiety and LUTS, and the moderating influence of systemic inflammation, in the presence of other biopsychosocial confounders.	26445118
Acute inflammation, Hemorrhagic diarrhea	Altered Intercellular Communication	It causes bouts of acute intestinal inflammation, in an unpredictable relapsing-remitting course, with bloody diarrhoea and extreme urgency to access a toilet.	26445224
Inflammation	Altered Intercellular Communication	We speculate that the former may be due to systemic inflammation and the latter to a higher socio-economic status.	26446117
Inflammation	Altered Intercellular Communication	BT alteration in these patients may be associated with brain perfusion and metabolism rather than other factors such as systemic inflammation and body temperature.	26446147
Retinitis	Altered Intercellular Communication	APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration.	26446211
Inflammation, Hyperplastic Polyp	Altered Intercellular Communication	In the context of APOE-dependent subretinal inflammation in Cx3cr1(GFP/GFP) mice, the APOE4 allele led to diminished APOE and CCL2 levels and protected Cx3cr1(GFP/GFP) mice against harmful subretinal MP accumulation observed in Cx3cr1(GFP/GFP)TRE3 mice.	26446211
methyldopa, Inflammation, Abnormal degeneration	Altered Intercellular Communication	Our study is the first to show how APOE2 provokes and APOE4 inhibits the cardinal AMD features, inflammation, degeneration, and exaggerated neovascularization.	26446211
methyldopa, Inflammation	Altered Intercellular Communication	They emphasize the role of APOE in inflammation and inflammation in AMD.	26446211
Kimura Disease	Altered Intercellular Communication	Kimura's disease is a rare, chronic inflammatory condition of unknown etiology; with a predilection in the head and neck region.	26446335
Inflammation, Islet Cell Tumor	Altered Intercellular Communication	FP PET/CT results were due to unspecific liver uptake, post-surgical inflammation and pancreatic neuroendocrine tumour.	26446694
Pain Distress Question, Inflammation, hyperthermia treatment	Altered Intercellular Communication	However, we report the unusual aspect of the bone scan in a 3-year-old child who was referred to explore an isolated pain of his lower left limb, with hyperthermia and markers of inflammation.	26447375
Communicable Diseases, Aortitis	Altered Intercellular Communication	Aortitis is a generic term defined as an inflammatory condition involving the aortic wall, of infectious or noninfectious origin.	26447376
Inflammation, gastrointestinal, Granuloma	Altered Intercellular Communication	Anisakis can produce persistent local inflammation and granuloma, and larvae have been incidentally found in gastrointestinal (GI) tumors.	26448021
Bone Diseases, HD Term Type, Inflammation, Calcinosis	Altered Intercellular Communication	The markers studied here may be involved in the calcification of vessels seen in HD patients due to a combination of inflammation and bone disease.	26448366
Inflammation, Morbidity - disease rate	Altered Intercellular Communication	Mini-extracorporeal circulation (MECC) units were developed to reduce postoperative morbidity, transfusion requirements, and inflammation associated with conventional on-pump coronary artery bypass (ONCAB) surgery without the technical demands of the off-pump (OPCAB) technique.	26448506
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	IL-1b is involved in the induction and maintenance of chronic inflammation in rheumatoid arthritis (RA).	26448682
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	We are first to observe a selective increase in monocyte p38 mitogen-activated protein kinase activity in metabolic syndrome and suggest it as a pivotal molecular target for ameliorating insulin resistance and inflammation.	26449239
Inflammation, Neoplasms, S100A4 protein, human, Communicable Diseases, Virus Diseases	Altered Intercellular Communication	It has been estimated that 15%-20% of human tumours are driven by infection and inflammation, and viral infections play an important role in malignant transformation.	26449432
Inflammation, Osteoporosis, Postmenopausal	Altered Intercellular Communication	Given the important role of IL-31 in inflammation, we measured its serum levels in postmenopausal osteoporotic patients.	26449657
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Adipose tissue inflammation contributes to the development of complications, such as insulin resistance and type 2 diabetes mellitus.	26449750
Inflammation, Myeloid Leukemia, Chronic	Altered Intercellular Communication	We previously reported that plasma levels of N(e)-(carboxymethyl)lysine (CML) were decreased in obese subjects resulting from CML accumulation in adipose tissue and that this CML accumulation plays an important role in adipose tissue inflammation.	26449750
Inflammation, Myeloid Leukemia, Chronic, Obesity, Abdominal, Obesity	Altered Intercellular Communication	Obesity, in particular central obesity, is characterized by greater levels of LGI but by lower levels of circulating CML; the latter significantly explaining a portion of the positive association between central obesity and inflammation.	26449750
Inflammation	Altered Intercellular Communication	The avb6 integrin is a cell surface adhesion molecule that plays critical roles in the injury and inflammation processes.	26449830
Inflammation	Altered Intercellular Communication	Elevated risperidone serum concentrations during acute inflammation, two cases.	26449925
Seizures, Inflammation, selenium, Status Epilepticus	Altered Intercellular Communication	Acute-phase proteins, such as procalcitonin (PCT), C-reactive protein (CRP) and albumin, may relate with course and outcome in status epilepticus (SE), as seizures bring about inflammation, changes of cytokine levels and blood-brain barrier breakdown.	26450065
Inflammation, Urinary tract infection	Altered Intercellular Communication	As urinary tract infection (UTI) represents a common source of inflammation during pregnancy, we tested whether presence of UTI during pregnancy increased the odds of developing PE.	26450405
Inflammation, hypertensive nephropathy	Altered Intercellular Communication	Inflammation mediated by nuclear factor-kB (NF-kB) plays a critical role in the pathogenesis of hypertensive nephropathy (HN).	26450610
Inflammation, Atherosclerosis	Altered Intercellular Communication	Convincing evidence has identified inflammation as an initiator of atherosclerosis, underpinning CVD.	26450630
Inflammation	Altered Intercellular Communication	We investigated (i) whether dietary inflammation, as measured by the 'dietary inflammatory index (DII)', was predictive of 5-year CVD in men and (ii) its predictive ability compared with that of SFA intake alone.	26450630
vascular inflammations	Altered Intercellular Communication	CVD clinical guidelines and public health recommendations may have to expand to include dietary patterns in the context of vascular inflammation.	26450630
Communicable Diseases, Noninfiltrating Intraductal Carcinoma, Inflammation	Altered Intercellular Communication	Development of DCI is multifactorial, and inflammation, with or without infection, is one of the factors independently associated with development of DCI and poor outcome.	26450848
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Etiologies were divided into 3 prognostic categories: Group 1, chemical injuries (7 eyes); Group 2, immune-based inflammation (4 eyes); and Group 3, noninflammatory diseases (9 eyes).	26451369
Communicable Diseases, Inflammation, Parasitemia, Skeletal muscle structure	Altered Intercellular Communication	Consistent with these data, Gal-1 deficient (Lgals1-/-) mice showed increased parasitemia, reduced signs of inflammation in heart and skeletal muscle tissues, and lower survival rates as compared to wild-type (WT) mice in response to intraperitoneal infection with T. cruzi Tulahuen strain.	26451839
Takayasu Arteritis	Altered Intercellular Communication	Contrast-enhanced ultrasonography in Takayasu arteritis: watching and monitoring the arterial inflammation.	26452525
Vasculitis	Altered Intercellular Communication	This pathological enhancement indicates neovascularisation of the arterial wall, which is supposed to correlate with active vascular inflammation.	26452525
Refractory anemias, Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	In rheumatoid arthritis (RA), treat-to-target strategies require instruments for valid detection of joint inflammation.	26452538
Inflammation	Altered Intercellular Communication	We developed and validated within the same cohort an algorithm for detection of joint inflammation by OST with US as reference.	26452538
Refractory anemias, Inflammation	Altered Intercellular Communication	In this pilot study, OST performed moderately in the detection of joint inflammation in patients with RA.	26452538
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Breast cancer risk reduction may be possible for U.S. women with dietary consumption of higher o-3, which has anti-inflammatory properties, in concert with lower o-6, which induces inflammation.	26452606
Inflammation, Fever, CTCAE, Anemia	Altered Intercellular Communication	We discuss the clinical and pathologic features of this lesion suggesting that its regressive changes may be associated with inflammation and can cause systemic symptoms such as fever and anemia.	26453091
Airway structure	Altered Intercellular Communication	Airway inflammation and proinflammatory mediators in lung tissue and BAL fluid were determined.	26453516
HD Term Type, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Emerging evidence highlights the strong correlation of oxidative stress with chronic inflammation and cardiovascular disease, which are highly prevalent in most patients on maintenance haemodialysis (HD) and are a major risk factor for mortality in this population.	26453922
Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Diabetes Mellitus, Fatty Liver Disease	Altered Intercellular Communication	Nine hundred and thirty-nine participants in the Edinburgh Type 2 Diabetes Study underwent investigation including liver ultrasound and non-invasive measures of non-alcoholic steatohepatitis (NASH), hepatic fibrosis and systemic inflammation.	26454513
Inflammation, Fibrosis Assessment, Chronic liver disease, Fatty Liver Disease	Altered Intercellular Communication	Higher levels of systemic inflammation, NASH and hepatic fibrosis markers were associated with both unknown prevalent and incident clinically significant chronic liver disease (allP < 0.001).	26454513
Diabetes Mellitus	Altered Intercellular Communication	Brain-derived neurotrophic factor (BDNF) is associated with systemic inflammatory conditions, such as diabetes.	26454822
Cholangiocarcinoma, FBN2 wt Allele, Malignant Neoplasms, Inflammation	Altered Intercellular Communication	Cholangiocarcinoma (CCA), which is a poor prognosis malignancy that arises from the malignant transformation of cholangiocytes, is associated with chronic inflammation of the biliary epithelium.	26455324
Inflammation, FBN2 wt Allele	Altered Intercellular Communication	Thus far, the molecular mechanisms of the origin and neoplastic processes of CCA that are promoted by inflammation are still unclear and need to be fully elucidated.	26455324
Inflammation, Primary malignant neoplasm, FBN2 wt Allele	Altered Intercellular Communication	Surprisingly, let-7c/miR-99a/miR-125b cluster also significantly decreased the ability of CCA cells for cancer stem cell-like mammosphere generation by downregulating CD133 and CD44, which suggests the pivotal roles of let-7c, miR-99a and miR-125b in CCA by regulating both inflammation and stem-like properties.	26455324
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Levels of High-Density Lipoprotein Cholesterol are Associated With Biomarkers of Inflammation in Patients With Acute Coronary Syndrome.	26456205
Pain Distress Question, Inflammation	Altered Intercellular Communication	Emerging evidence proposes a link between immune changes and pain, which is consistent with the inflammation theory of aging and the increased incidence of age-related diseases.	26456458
Inflammation, Pain Distress Question	Altered Intercellular Communication	Sterile inflammation after intravitreal aflibercept injection typically presents without pain, and the visual outcomes are generally favorable.	26457038
Inflammation, Atherosclerosis	Altered Intercellular Communication	Circulating and coronary CTRP9 plays an important role in the inflammation and coronary atherosclerosis of CAD patients.	26457306
Inflammation	Altered Intercellular Communication	Distinct lymphocyte subpopulations have been implicated in the regulation of glucose homeostasis and obesity-associated inflammation in mouse models of insulin resistance.	26458065
vascular inflammations	Altered Intercellular Communication	[A case of MPO-ANCA positive hypertrophic pachymeningitis associated with vascular inflammation in the kidney biopsy].	26458570
vascular inflammations	Altered Intercellular Communication	The presence of vascular inflammation in the kidney biopsy led us to consider that this patient may show progression to the systemic type of MPO-ANCA-positive hypertrophic pachymeningitis.	26458570
Inflammation, Rosacea	Altered Intercellular Communication	The intensity of perifollicular inflammation and the presence of follicular inflammatory reactions were dependent on the severity of rosacea in both subtype groups.	26460622
Mesenteric Panniculitis	Altered Intercellular Communication	Mesenteric panniculitis is an underdiagnosed inflammatory condition of unknown etiology that involves the mesenteric adipose tissue.	26462046
Inflammation, Ischemia	Altered Intercellular Communication	Inflammation is associated with a reduced number of pro-angiogenic Tie-2 monocytes and endothelial progenitor cells in patients with critical limb ischemia.	26462497
CLU protein, human, Ischemia, Inflammation	Altered Intercellular Communication	Critical limb ischemia (CLI) is characterized by a severe, chronic inflammatory response; thus, progression of the disease might be related to the deleterious effects of inflammation on pro-angiogenic cells.	26462497
CLU protein, human, Inflammation	Altered Intercellular Communication	We found a strong association of diverse inflammatory markers with a reduced proportion of pro-angiogenic TEM or EPC in patients with CLI, giving rise to the speculation that a severe chronic inflammation might lead to deleterious effects on TEM and EPC, possibly interfering with angiogenesis, thus promoting an aggravation of the disease.	26462497
Inflammation, Diverticulitis, Diverticulum	Altered Intercellular Communication	He was diagnosed with diverticular colitis based on findings of redness around diverticula in the sigmoid colon and biopsy findings of non-specific inflammation.	26464173
Interstitial inflammation, Swelling, Syphilis, Dermatitis, Acanthosis	Altered Intercellular Communication	Combinations of endothelial swelling, interstitial inflammation, irregular acanthosis, and elongated rete ridges should raise the possibility of syphilis, along with the presence of vacuolar interface dermatitis with a lymphocyte in nearly every vacuole and lymphocytes with visible cytoplasm.	26464219
Inflammation, Asthma	Altered Intercellular Communication	In asthma, inflammation affects both the proximal and distal airways and may induce significant hyperinflation (HI).	26466328
ARCN1 gene, Inflammation, Pancreatitis, Sarcoidosis, Chronic Obstructive Airway Disease, Inflammatory disorder, MS gene	Altered Intercellular Communication	To further discriminate between disease-specific and general inflammation we included miRNA expression data from other inflammatory diseases (inflammation controls (IC): 24 chronic obstructive pulmonary disease (COPD), 23 multiple sclerosis, 38 pancreatitis and 45 sarcoidosis cases) as well as 70 healthy controls from previous studies.	26466382
Inflammation, Cerebral Aneurysm, Rupture	Altered Intercellular Communication	A growing body of evidence suggests that inflammation plays a crucial role in cerebral aneurysm initiation, progression, and rupture.	26466586
Inflammation, Nephrosclerosis, Brucellosis	Altered Intercellular Communication	The present case demonstrates that persistent subclinical inflammation can lead to malignant nephrosclerosis in familial Mediterranean fever patients with this genotype.	26466703
Adult-Onset Still Disease, Orbital Pseudotumor	Altered Intercellular Communication	Orbital inflammation has been rarely associated with adult-onset Still's disease (AOSD).	26466709
Inflammation, Enlargement of lacrimal gland	Altered Intercellular Communication	We herein describe two AOSD patients who developed lacrimal gland enlargement with inflammation spreading to the contiguous tissues in the orbit.	26466709
Dacryoadenitis, Orbital Pseudotumor	Altered Intercellular Communication	We speculate that dacryoadenitis and orbital inflammation are manifestations of AOSD.	26466709
Autoimmune Diseases, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis is an autoimmune disease characterized by joint inflammation that affects approximately 1% of the general population.	26466969
Inflammation, Neoplasms	Altered Intercellular Communication	Comparisons of CD66b and the CD66b/CD3 ratio according to N status, tumour location, recurrence, inflammation grade, and histological grade did not reach statistical significance.	26467671
methyldopa, Inflammation	Altered Intercellular Communication	Our results show that SNPs associated with complement activation and inflammation significantly contribute to AMD risk, separately from the risk explained by the 19 known risk SNPs.	26467978
Inflammation	Altered Intercellular Communication	Tangeretin from Citrus reticulate Inhibits Respiratory Syncytial Virus Replication and Associated Inflammation in Vivo.	26468759
Pneumonitis	Altered Intercellular Communication	Moreover, a luminex assay indicated tangeretin relieved RSV-induced lung inflammation by attenuating interleukin (IL)-1b secretion.	26468759
Inflammation, Respiratory Syncytial Virus Infections, Pneumonitis	Altered Intercellular Communication	This study demonstrates that tangeretin inhibited RSV replication and RSV-induced lung inflammation in vivo and may be useful in preventing and treating RSV infections and inflammation.	26468759
Inflammation, Chronic Obstructive Airway Disease, Failure (biologic function)	Altered Intercellular Communication	Chronic obstructive pulmonary disease is characterized, in part, by chronic inflammation that persists even after smoking cessation, suggesting that a failure to resolve inflammation plays an important role in the pathogenesis of the disease.	26468975
Inflammation, Chronic Obstructive Airway Disease, Pulmonary Emphysema	Altered Intercellular Communication	Here, we report that proresolving signaling and metabolic pathways are disrupted in lung tissue from patients with chronic obstructive pulmonary disease, suggesting that supplementation with proresolving lipid mediators might reduce the development of emphysema by controlling chronic inflammation.	26468975
Cessation of life, Inflammation, Pulmonary Emphysema, Hypertrophy	Altered Intercellular Communication	Resolvin D1 was associated with a reduced development of cigarette smoke-induced emphysema and airspace enlargement, with concurrent reductions in inflammation, oxidative stress, and cell death.	26468975
Inflammation, Oral pain	Altered Intercellular Communication	ECC might negatively affect children's nutritional status, which might be mediated by the depth of decay, chronic inflammation, and mouth pain.	26469655
Diabetes Mellitus	Altered Intercellular Communication	Diabetes is already considered as an inflammatory condition with different cytokines being implicated in its physiopathology.	26469782
Inflammation, Dirofilariasis	Altered Intercellular Communication	The most frequent presentation of human dirofilariasis is a single submucosal nodule without signs of inflammation.	26470974
Inflammation, Scleritis	Altered Intercellular Communication	Bilateral posterior scleritis is an uncommon but severe inflammation of the posterior sclera.	26471249
Presenile dementia, Inflammation	Altered Intercellular Communication	Cerebral amyloid angiopathy-related inflammation: A potentially reversible cause of dementia with characteristic imaging findings.	26471406
Cerebral Amyloid Angiopathy, Inflammation	Altered Intercellular Communication	Cerebral amyloid angiopathy with inflammation (CAA-I) is a less well-recognized clinically and radiologically distinct subtype of CAA.	26471406
Inflammation	Altered Intercellular Communication	Contrast-enhancing MS lesions are important markers of active inflammation in the diagnostic work-up of MS and in disease monitoring with MR imaging.	26471751
Inflammation, Neoplasms	Altered Intercellular Communication	The occurrence of hyaluronan in smokers may have implications in the development of vocal fold inflammation and tumor initiation as hyaluronan is an important molecule in these processes.	26471808
Inflammation, Retinal Hemorrhage, Ocular Toxoplasmosis	Altered Intercellular Communication	To report a case with unilateral preexisting ocular toxoplasmosis (OT) and newly occurred active retinochoroidal inflammation associated with white-centered retinal hemorrhages (Roth spots) in the healthy eye.	26472315
Chorioretinitis	Altered Intercellular Communication	OT may be one differential diagnosis of patients suffering Roth spots in association with retinochoroidal inflammation.	26472315
Inflammation, Eosinophilic disorder, Communicable Diseases, Respiratory Syncytial Virus Infections, Respiratory Hypersensitivity	Altered Intercellular Communication	Blocking IL-33 with antibodies or using an IL-33 receptor knockout mouse during infection was sufficient to inhibit RSV immunopathogenesis (i.e., airway hyperresponsiveness, Th2 inflammation, eosinophilia, and mucus hyperproduction); whereas administration of IL-33 to adult mice during RSV infection was sufficient to induce RSV disease.	26473724
Refractory Cytopenia of Childhood, Inflammation, Pituitary Adenoma	Altered Intercellular Communication	Repeated chronic inflammation, such as under circumstances of ruptured Rathke's cleft cyst (RCC), is known as the fundamental basis of various pathological changes including neoplastic change, therefore to examine accurate incidence of pituitary adenomas is important for the preventive medicine.	26473987
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	There is a complicated relationship between adipokines and low-grade inflammation in obesity and cardiovascular disease (CVD).	26474157
Inflammation, Diabetes Mellitus, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Health-Related Quality of Life in Relation to Obesity Grade, Type 2 Diabetes, Metabolic Syndrome and Inflammation.	26474291
Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Obesity, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	These conditions are i) grade of obesity with and without type 2 diabetes (T2D), ii) metabolic syndrome (MetS), and iii) level of inflammation.	26474291
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, ETV3 wt Allele, Obesity	Altered Intercellular Communication	The impact of obesity on an individual's quality of life is enhanced by grade of obesity, T2D, MetS and inflammation and are mainly related to reduced physical health.	26474291
Inflammation, Pancreatic carcinoma	Altered Intercellular Communication	Impact of Intratumoral Inflammation on Survival After Pancreatic Cancer Resection.	26474423
Cessation of life, Inflammation, Neoplasms	Altered Intercellular Communication	We sought to evaluate whether inflammation in the primary tumor was associated with early death after surgical resection.	26474423
Inflammation, Neoplasms	Altered Intercellular Communication	Future studies evaluating the host response in multiple tumor compartments with advanced histologic techniques is needed to further elucidate the role of inflammation in PaC.	26474423
methyldopa, Retinitis	Altered Intercellular Communication	Wnt signaling may be disturbed in AMD patients, which could contribute to the retinal inflammation and increased A2E levels found in AMD.	26476672
Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Complement activation contributes significantly to inflammation-related damage in the heart after acute myocardial infarction.	26476955
Inflammation, Exophthalmos	Altered Intercellular Communication	His right eye showed exophthalmos, inflammation in the anterior chamber and iris neovascularization.	26477069
Inflammation, Cardiac sarcoidosis	Altered Intercellular Communication	The present study investigated whether (18)F-fluorodeoxyglucose-positron emission tomography (FDG-PET) uptake as an index of active inflammation in patients with cardiac sarcoidosis (CS) is associated with BMIPP and TL findings, and whether dual single-photon emission computed tomography (SPECT) can facilitate diagnosis of CS.	26477356
Inflammation, Hemophilic arthropathy	Altered Intercellular Communication	Inflammation and degeneration play roles in the pathogenesis of hemophilic arthropathy.	26479992
Sleeplessness	Altered Intercellular Communication	[Expressions of neurotransmitters in patients of insomnia differentiated as liver stagnation transforming into fire treated with acupuncture].	26480548
Inflammation, Anemia	Altered Intercellular Communication	Children living with HIV in India have a high prevalence of anemia mediated by iron deficiency, vitamin A deficiency and chronic inflammation.	26482352
Inflammation, Facial edema, Granuloma	Altered Intercellular Communication	Axial computed tomography (CT) scan of the paranasal sinuses showed a clear left facial swelling chronic inflammation and granulomata.	26482354
Inflammation, Obesity	Altered Intercellular Communication	These observations and the increasing global prevalence of obesity justify ongoing efforts to understand the role of obesity-induced inflammation in the pathogenesis and management of AP.	26482857
Inflammation	Altered Intercellular Communication	Inflammation resulted in the reduced colonic expression of ERBB2, GRB7, MIEN1, and PGAP3 (P = 1.0 x 10(-4)-1.0 x 10(-9)) and the increased colonic expression of IKZF3 and CSF3 (P = 2.4 x 10(-7)-3.5 x 10(-8)).	26484354
HD Term Type, Inflammation	Altered Intercellular Communication	Increased LIAT and inflammation were found to be closely associated with 2 years combined CV events and all-cause mortality in HD patients.	26484658
Gastrointestinal inflammation, Intestinal Diseases, Enterocytes	Altered Intercellular Communication	This study demonstrated enterocyte damage and intestinal inflammation in CF patients, and provides evidence for an inverse correlation between enteropathy and lung function.	26484665
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Increased MIF plasma levels promote vascular inflammation and development of atherosclerosis.	26485680
Proteinuria	Altered Intercellular Communication	TLR2-MyD88-NF-kB pathway is involved in tubulointerstitial inflammation caused by proteinuria.	26485683
Proteinuria	Altered Intercellular Communication	Several studies have suggested that proteinuria initiates tubulointerstitial inflammation, while the mechanisms have not been fully understood.	26485683
Proteinuria	Altered Intercellular Communication	In this study, we hypothesized whether the activation of the TLR2-MyD88-NF-kB pathway is involved in tubulointerstitial inflammation induced by proteinuria.	26485683
Proteinuria, Moist	Altered Intercellular Communication	In summary, we demonstrated that proteinuria may exhibit an endogenous danger-associated molecular pattern (DAMP) that induces tubulointerstitial inflammation via the TLR2-MyD88-NF-kB pathway activation.	26485683
Inflammation	Altered Intercellular Communication	However, the connection between this lysosomal storage and inflammation is not clear.	26486234
Parkinson Disease, Inflammation	Altered Intercellular Communication	Moreover, this link between lysosomal storage, impaired autophagy, and inflammation may have implications relevant to both Parkinson disease and the aging process.	26486234
Cholecystitis, Acute Cholecystitis	Altered Intercellular Communication	Does the Tokyo guidelines predict the extent of gallbladder inflammation in patients with acute cholecystitis?	26486453
Inflammation	Altered Intercellular Communication	The preoperative severity grades were compared with the histological extent of inflammation.	26486453
Cholecystitis	Altered Intercellular Communication	43, p = 0.01) between the preoperative severity grade and the extent of gallbladder inflammation on histopathology.	26486453
Inflammation	Altered Intercellular Communication	However, the Tokyo guidelines may have a tendency to underestimate the extent of inflammation in male patients with severity grade I and over estimate the difficulty of dissection in severity grade II.	26486453
Inflammation, Fibrosis Assessment, Neoplasms	Altered Intercellular Communication	Accuracy of T-staging was significantly worse after CRT (0.16) than after CT (0.43), obviously due to difficulty in distinguishing residual tumor from treatment-associated fibrosis and inflammation.	26487231
Proteinuria, Inflammation, Kidney Failure, Chronic Kidney Diseases	Altered Intercellular Communication	Lact supplementation mitigated the systemic inflammation and proteinuria associated with renal failure, suggesting that in the gut microbiota, Lact plays a protective role against the progression of CKD.	26487672
Inflammation	Altered Intercellular Communication	It aids in delineating severe inflammation requiring surgery without substantial delay.	26488396
Airway structure, Tissue damage	Altered Intercellular Communication	Asthma is characterized by airway inflammation, and bronchial airways are particularly susceptible to oxidant-induced tissue damage.	26490046
Inflammation, Cholesteatoma	Altered Intercellular Communication	It might suggest that the higher the expression of MMP-9 the stronger the inflammation -accompanied cholesteatoma.	26490574
Inflammation, Neoplasms, Malignant Neoplasms	Altered Intercellular Communication	Inflammation and tumor immune microenviroment are critical factors for prognosis in numerous cancers.	26490984
Inflammation, Disease	Altered Intercellular Communication	The CFs from a published meta-analysis were appropriate for use in this population with a high prevalence of Hb disorders and inflammation.	26491125
Renal Insufficiency, Inflammation	Altered Intercellular Communication	Significance of Neutrophil Gelatinase-Associated Lipocalin Level-to-Serum Creatinine Ratio for Assessing Severity of Inflammation in Patients with Renal Dysfunction.	26491688
Renal Insufficiency, Inflammation	Altered Intercellular Communication	In short, the NGAL/sCr ratio may offer useful information when screening patients with both systemic inflammation and renal dysfunction.	26491688
Inflammation, Calcinosis	Altered Intercellular Communication	Tissue sections were stained with hematoxylin and eosin, Masson trichrome, and Movat pentachrome, and were graded for inflammation, tissue substitute degeneration, neointima formation, and calcification.	26492092
Inflammation	Altered Intercellular Communication	Inflammation and tissue degeneration were greater in PhotoFix pericardium compared to autologous pericardium but were no more than moderate.	26492092
Inflammation, Calcinosis, Abnormal degeneration	Altered Intercellular Communication	PhotoFix bovine pericardium is associated with more inflammation and material degeneration but calcification, and neointima formation are similar to autologous pericardium.	26492092
Coinfection, Inflammation, Ear Inflammation	Altered Intercellular Communication	External otitis is a diffuse inflammation around the external auditory canal and auricle, which is often occurred by microbial infection.	26492256
Inflammation, Metabolic Syndrome X, Carotid Intima-Media Thickness	Altered Intercellular Communication	Childhood metabolic syndrome, inflammation and carotid intima-media thickness.	26492305
Inflammation, ETV3 wt Allele, Atherosclerosis	Altered Intercellular Communication	MetS in childhood is associated with subclinical atherosclerosis in an Australian Aboriginal population and the effects appear to be mediated by increased inflammation.	26492305
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with Th2-dominant inflammation.	26492334
Parkinson Disease, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Thiazolidinediones, a class of medications indicated for the treatment of type 2 diabetes mellitus, reduce inflammation and have been shown to provide a therapeutic benefit in animal models of Parkinson disease.	26493264
Inflammation, Neoplasms	Altered Intercellular Communication	NLR may reflect host immunity and systemic inflammation that facilitates tumor growth.	26493696
palladium, Vascular Diseases, Inflammation	Altered Intercellular Communication	We evaluated circulating S100A12 and sRAGE in relation to vascular disease, inflammation, nutritional status, and mortality risk in peritoneal dialysis (PD) patients.	26493750
palladium, Inflammation, Vascular Diseases	Altered Intercellular Communication	Soluble RAGE was inversely related to body mass indices while S100A12 associated with increased inflammation, PCVD, and mortality, suggesting that S100A12 may identify PD patients at high risk for vascular disease and increased mortality.	26493750
Primary malignant neoplasm	Altered Intercellular Communication	Incidental adrenal masses detected in the presence history of cancer should always be subjected to hormonal evaluation.	26494041
Inflammation, atherosclerotic	Altered Intercellular Communication	Rather, g' fibrinogen concentrations seem to reflect general inflammation that accompanies and may contribute to atherosclerotic CVD, instead of g' fibrinogen being a causal risk factor.	26494231
Sepsis, Inflammation, Observation Method - Coagulation, Communicable Diseases	Altered Intercellular Communication	Sepsis is characterized by systemic activation of inflammation and coagulation in response to infection.	26494232
Inflammation, hepcidin, Anemia	Altered Intercellular Communication	Hepcidin-25 production is stimulated by systemic inflammation, and it interferes with iron utilization, leading to anemia.	26496240
Inflammation, Hemorrhage, Neoplasms, Hookworm Infections, Lymphoma, Ulcer, Vascular anomaly, Crohn Disease	Altered Intercellular Communication	Patients who underwent single-balloon enteroscopy were found to have neoplasms (most common age group: 14-45 years, most common lesion location: jejunum), lymphoma (46-59 and 60-74 years, ileum), protuberant lesions (45-59 years, jejunum), inflammation (14-45 and 46-59 years, ileum), benign ulcers (14-45 years, jejunum), diverticulum (14-45 years, ileum), vascular malformations (60-74 years, jejunum), polyps (14-45 years, jejunum), Crohn's disease (14-45 years, jejunum), hookworm infection (14-45 years, jejunum), lipid pigmentation (14-45 and 46-59 years, jejunum), undetermined bleeding (46-59 years, ileum), or undetermined stenosis (31 years, duodenum).	26496270
Cessation of life, Inflammation, Malnutrition	Altered Intercellular Communication	The mortality rates and causes of death were analyzed.The analytic results demonstrated patients in the high BCL group had a significantly higher prevalence of malnutrition and inflammation than patients in the low and intermediate BCL groups.	26496294
Cancer of Urinary Tract, Inflammation	Altered Intercellular Communication	Recently, many studies explored the role of inflammation parameters in the prognosis of urinary cancers, but the results were not consistent.	26496339
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The modified Glasgow Prognostic Score (mGPS), a systemic inflammation marker, is a prognostic marker in various types of cancers.	26496339
Inflammation	Altered Intercellular Communication	An MRI score >= 4 indicated the best results, with sensitivity of 86%, specificity of 79%, positive predictive value of 80%, negative predictive value of 85%, and accuracy of 82% for pouch inflammation.	26496569
Inflammation	Altered Intercellular Communication	In patients who have undergone IPAA surgery, the MRE findings strongly correlate with the pouch endoscopic findings with high sensitivity and positive predictive value for pouch inflammation.	26496569
Inflammation, Hemorrhage, Vasculitis, CTCAE	Altered Intercellular Communication	The four subjects had manifestations of vasculitis including hemorrhage within the cochlea and vestibule, and inflammation and occlusion of vessels in the lateral cochlear wall and the vasa nervorum of the facial nerve.	26496669
Inflammation, Brain Injuries, Postoperative cognitive dysfunction	Altered Intercellular Communication	Postoperative cognitive dysfunction after inhalational anesthesia in elderly patients undergoing major surgery: the influence of anesthetic technique, cerebral injury and systemic inflammation.	26497059
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Estrogens have a complex role in inflammation and growing evidence suggests that these hormones may impact IBD pathogenesis.	26497217
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Estrogens have a complex role in inflammation and growing evidence suggests that these hormones may impact IBD pathogenesis.	26497217
Inflammation, Damage, Muscular Atrophy	Altered Intercellular Communication	Muscle atrophy results from a range of physiological conditions, including immobilization, spinal cord damage, inflammation and aging.	26497270
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Synovial angiogenesis and inflammation are observed across the full range of OA severity.	26497299
Communicable Diseases, Inflammation	Altered Intercellular Communication	C-reactive protein (CRP) is a common marker of acute or chronic inflammation and infection.	26497919
Inflammation, Pain, Postoperative	Altered Intercellular Communication	The new robotic single-site platform might offer potential benefits on local inflammation and postoperative pain due to its technological advantages.	26497946
Myocarditis	Altered Intercellular Communication	Immunohistological examination revealed myocardial inflammation in 2 individuals (4%).	26498214
ARCN1 gene, Inflammation	Altered Intercellular Communication	Alternative treatment options such as combined theophylline with low-dose CsA, that inhibit these pro-inflammatory cells, may reduce systemic inflammation in COPD.	26498345
Inflammation, Squamous cell carcinoma of vulva	Altered Intercellular Communication	Chronic inflammation induced by lichen sclerosus (LS) or human papilloma virus (HPV) precedes vulvar squamous cell carcinoma (vulvar SCC).	26499936
Autoimmune Diseases, Inflammation, Cerebral Atherosclerosis, Atherosclerosis	Altered Intercellular Communication	Higher circulating anti-Hsp60 is associated with advanced cerebrovascular atherosclerosis as a consequence of the autoimmunity part of the inflammation and bursting of atherosclerosis.	26500006
Pancreatic carcinoma	Altered Intercellular Communication	Prognostication by inflammation-based score in patients with locally advanced pancreatic cancer treated with chemoradiotherapy.	26500167
Inflammation, Hypoxemia	Altered Intercellular Communication	Results Even though patients exhibited systemic inflammation and anemic hypoxemia, dCA was similar to healthy volunteers (gain: 1.24 [0.94-1.49] vs. 1.22 [1.06-1.34] cm mm Hg-1 s-1, p = 0.97; phase: 0.33 [0.15-0.56] vs. 0.69 [0.50-0.77] rad, p = 0.09).	26501221
Inflammation, Surgical incisions, Acute onset pain	Altered Intercellular Communication	Persistent incisional pain is common after cardiac surgery and is believed to be in part related to inflammation and poorly controlled acute pain.	26501386
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Abdominal aortic aneurysms are associated with chronic inflammation within the aortic wall, and previous studies have suggested that chronic inflammation may be a consequence of a dysregulated and persistent autoimmune response.	26501863
Inflammation, Postoperative Complications, GDC Comorbidity Terminology	Altered Intercellular Communication	These patients had similar comorbid conditions compared with patients without inflammation but significantly greater numbers of major postoperative complications after EVAR (23.5% vs 3.6%; P = .02) and overall postoperative complications after EVAR (27.5% vs 7.1%; P = .03).	26501863
Inflammatory abnormality of the eye, Vitreous strands	Altered Intercellular Communication	Scores obtained using the VHRF algorithm may be obtained from OCT images that include the vitreous and could provide a rapid, noninvasive clinical correlate for ocular inflammation.	26502148
Autoimmune Diseases, Myocarditis	Altered Intercellular Communication	In addition, the association of LVDD with myositis-specific or -associated autoantibodies and high cardiac (99m) Tc-PYP uptake supports the notion of underlying autoimmunity and myocardial inflammation in patients with PM/DM.	26502301
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Cancer-related inflammation affects many aspects of malignancy, including proliferation and survival of malignant cells, angiogenesis, and therapeutic response.	26502851
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Some biomarkers representing the degree of systemic inflammation, such as the Glasgow prognostic score, NLR and PLR, have been shown to have prognostic value in many kinds of cancer patients.	26502851
Inflammation, Chronic disease	Altered Intercellular Communication	The red cell distribution width-platelet ratio (RPR), a novel inflammatory marker is currently used to predict inflammation in chronic diseases.	26503078
Inflammation, Carcinogenesis	Altered Intercellular Communication	As inflammation and androgen pathways are implicated in prostate carcinogenesis, additional studies of anti-inflammatory medications in relation to these PCa subtypes are warranted.	26503111
Inflammation	Altered Intercellular Communication	Such changes in other brain structures may explain gliosis, dendritic volume increase, or inflammation.	26503297
Acute inflammation	Altered Intercellular Communication	Patients undergoing lung resection and one-lung ventilation exhibited significant postoperative inflammation and oxidative damage.	26503312
Pneumonitis	Altered Intercellular Communication	Preoperative administration of N-acetylcysteine did not attenuate postoperative systemic or pulmonary inflammation or oxidative damage after lung resection.	26503312
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	Inflammation is a hallmark of cancer, yet the mechanisms that regulate immune cell infiltration into tumors remain poorly characterized.	26503598
Inflammation, Neoplasms	Altered Intercellular Communication	However, because the passive accumulation of ICG could not be used to discriminate tumours with inflammation, tumour-targeted fluorescence should be developed to solve this problem in the future.	26503731
Inflammation, Eosinophilic esophagitis, Immune-mediated	Altered Intercellular Communication	Eosinophilic esophagitis is an immune-mediated disease resulting in inflammation of the esophagus.	26505065
Inflammation, Metabolic Syndrome X, Cardiovascular Diseases, ETV3 wt Allele, Diabetes Mellitus	Altered Intercellular Communication	Metabolic syndrome (MetS) predisposes to both diabetes and cardiovascular disease, and inflammation is pivotal in MetS.	26505293
osteitis pubis, Inflammation	Altered Intercellular Communication	Osteitis pubis or symphysitis pubis is a rare occurring non-infectious inflammation of the symphysis, the adjacent pubic bones and surrounding tissue.	26506827
Inflammation, Malignant neoplasm of endometrium	Altered Intercellular Communication	The relation between inflammation deriving from diet and endometrial cancer risk has not yet been investigated.	26507451
Inflammation, Lymphovascular	Altered Intercellular Communication	Delay in diagnosis, depth of invasion, marked inflammation, lymphovascular invasion, and regional lymph node status are important prognostic factors.	26508372
Inflammation, Progranulins	Altered Intercellular Communication	Whereas resistin represents a systemic marker of inflammation, CSF progranulin levels strongly depend on the underlying disease and dysfunction of blood-CSF barrier.	26509463
Inflammation, Communicable Diseases, Granulation finding, Scab, Mucous membrane edema	Altered Intercellular Communication	Objective data was obtained by blinded endoscopic scoring to rate mucosal edema, inflammation, granulation, crusting, infection, and synechiae formation on postoperative weeks 1, 3, and 6.	26509639
Scab, Inflammation	Altered Intercellular Communication	In objective measures, CMC gel nearly reaches significance for more postoperative debridement, with increased crusting and inflammation.	26509639
Crohn Disease, Abdominal symptom	Altered Intercellular Communication	Inflammation-related enteric dysmotility has been postulated as a cause for abdominal symptoms in Crohn's disease (CD).	26509756
Abdominal symptom	Altered Intercellular Communication	Reduced motility variance in morphologically normal SB is associated with patient symptoms and fecal calprotectin levels, supporting the hypothesis that inflammation-related enteric dysmotility may explain refractory abdominal symptoms in CD.	26509756
Inflammation, Data types - Address	Altered Intercellular Communication	We therefore conclude that S. aureus may cause and promote inflammation in the skin of AD children through concomitant Th2 activation and the silencing of resident Treg cells.	26510097
Inflammation, Lung Diseases, Interstitial, Fibrosis Assessment	Altered Intercellular Communication	Interstitial lung disease (ILD) includes a diverse group of respiratory conditions characterised by inflammation and fibrosis of the interstitium.	26510140
palladium, Inflammation	Altered Intercellular Communication	Incident PD patients treated with low GDP solution have less severe systemic inflammation but trends of less ultrafiltration, and more fluid accumulation.	26510186
Necrotizing granulomatous inflammation, Squamous cell carcinoma	Altered Intercellular Communication	Histological examination of a mass of few fused lymph nodes, isolated from left laterocervical lymphadenectomy, showed metastatic squamous cell carcinoma with concomitant granulomatous inflammation.	26510425
Inflammation, Neurogenic Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Voxel-wise correlation analysis suggests that neuroinflammation is associated with localized amyloid deposition and glucose metabolism over time, however, the level of inflammation could also occur independently of amyloid pathology, especially in the later stages of Alzheimer's disease.	26510952
Inflammation, Ischemia, Guillain-Barre Syndrome, Familial, Acute Infective Polyneuritis	Altered Intercellular Communication	Both chronic inflammation and nerve ischaemia in DM may intervene in the disease course of GBS, which is a prototype of acute inflammatory neuropathy.	26511168
ARCN1 gene, Inflammation	Altered Intercellular Communication	As C/EBPb exerts pro-inflammatory effects in the context of cigarette smoke, the elevated C/EBPb in advanced COPD may be an indication of a breakdown of regulatory mechanisms and excessive inflammation.	26511475
Intraocular inflammation	Altered Intercellular Communication	A 78-year-old, immunocompetent woman presented with subacute intraocular inflammation with high intraocular pressure, mimicking phacolytic glaucoma.	26511718
Cataract, Inflammation	Altered Intercellular Communication	Even though the cataract extraction was uneventful and adequate anti-inflammatory drugs were given, the inflammation did not subside as expected.	26511718
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	Obesity may contribute to cardiovascular disease (CVD) risk by eliciting chronic systemic inflammation and impairing the immune response to additional stressors.	26511907
Orbital Pseudotumor	Altered Intercellular Communication	Patients who were diagnosed with AAPOX at a French academic referral center for orbital inflammation between November 1996 and March 2013 were enrolled.	26512617
Acute Kidney Injury, CTCAE, Inflammation	Altered Intercellular Communication	Additional blood test showed inflammation and acute kidney injury Rifle category failure.	26512791
Granulomatous inflammation	Altered Intercellular Communication	A skin and kidney biopsy indicated a granulomatous inflammation.	26512791
Granulomatous inflammation	Altered Intercellular Communication	A complete workup for other causes of granulomatous inflammation was negative.	26512791
Inflammation, Primary malignant neoplasm, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	The association between number of teeth and low-grade systemic inflammation deserves consideration within the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam since the association between number of teeth and myocardial infarction has been established.	26513265
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	This study shows that number of teeth has a weak association with hsCRP, if any, thereby excluding this marker of low-grade systemic inflammation as a possible explanation for the association between number of teeth and myocardial infarction.	26513265
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	In NAFLD, serum b-trophin was related to liver fibrosis and inflammation.	26513612
Sepsis, Blood Coagulation Disorders	Altered Intercellular Communication	Sepsis is invariably accompanied by altered coagulation cascade; however, the precise role of phosphatidylserine (PS) in inflammation-associated coagulopathy in sepsis has not been well elucidated.	26513704
Inflammation, Gastrointestinal Neoplasms	Altered Intercellular Communication	Inflammation plays a major role in the development and progression of gastric and other gastrointestinal tumors.	26514504
Inflammation, Observation Method - Coagulation, Myocardial dysfunction, Immune dysregulation, Renal Insufficiency	Altered Intercellular Communication	In addition, blood markers potentially linked to frailty and related to the processes of inflammation, coagulation, hormonal dysregulation, nutrition, renal dysfunction, and heart dysfunction were determined.	26514748
Inflammation, Observation Method - Coagulation, Myocardial dysfunction, Immune dysregulation, Renal Insufficiency	Altered Intercellular Communication	In addition, blood markers potentially linked to frailty and related to the processes of inflammation, coagulation, hormonal dysregulation, nutrition, renal dysfunction, and heart dysfunction were determined.	26514748
Inflammation, Malignant Head and Neck Neoplasm, Fatigue	Altered Intercellular Communication	Fatigue is associated with inflammation in patients with head and neck cancer before and after intensity-modulated radiation therapy.	26515035
Inflammation, Primary malignant neoplasm, Fatigue	Altered Intercellular Communication	Although inflammation has been proposed as one of the potential mechanisms of fatigue in cancer patients, findings have not been consistent, and there is a dearth of longitudinal studies.	26515035
Inflammation, Fatigue, MMP8 wt Allele	Altered Intercellular Communication	In conclusion, our findings support the hypotheses that inflammation is associated with fatigue over time in HNC patients.	26515035
Inflammation, Fatigue	Altered Intercellular Communication	Future studies on how inflammation contributes to fatigue as well as strategies targeting inflammation to reduce fatigue are warranted.	26515035
Inflammation, Metabolic Syndrome X, Atherosclerosis	Altered Intercellular Communication	There is a widely approved influence of novel risk factors like the body fat distribution and the associated metabolic syndrome, subclinical inflammation, insulin resistance and prediabetic disturbances in glucose metabolism on the progression of atherosclerosis.	26515221
Inflammation	Altered Intercellular Communication	Inflammation induced by HBV infection presented a positive association with HPCs activation (P < 0.05).	26515593
Presenile dementia, Dementia, Vascular, VAD I protocol	Altered Intercellular Communication	Conversely, the involvement of central cholinergic neurotransmission in vascular dementia (VaD) is still under debate and data on Vascular Cognitive Impairment--No Dementia (VCI-ND) at risk for future VaD are lacking.	26515786
Gingivitis, Necrosis, Bothered by Vomiting, Diarrhea, Ulcer, Dental Plaque	Altered Intercellular Communication	As well as diarrhoea and vomiting, she had a very aggressive gingival inflammation with multiple ulcerations in both jaws and wide areas of necrotic bone, affecting the attached gingiva, and seemingly unrelated to dental plaque.	26516027
Inflammation, Infiltration, Monocytosis	Altered Intercellular Communication	Angiotensin II-infused Hmox1-/- mice had amplified endothelial inflammation in vivo, significantly increased aortic infiltration of pro-inflammatory CD11b+ Ly6C(hi) monocytes and Ly6G+ neutrophils and were marked by Ly6C(hi) monocytosis in the circulation and an increased blood pressure response.	26516175
Cushing Syndrome, hypothalamic-pituitary-adrenal axis	Altered Intercellular Communication	Hormonal assays were compatible with hypothalamic-pituitary-adrenal axis suppression, and iatrogenic Cushing's syndrome due to ritonavir-fluticasone interaction was considered.	26516245
Communicable Diseases, Inflammation	Altered Intercellular Communication	suspected infection, 2 or more criteria for systemic inflammation, and either systolic blood pressure <90 mmHg after a fluid bolus or lactate >4 mmol/liter.	26517062
ARCN1 gene, Inflammation, Exacerbation, Virus Diseases, Immune System Diseases	Altered Intercellular Communication	This study has established a signal of cytotoxic immune dysfunction and aberrant immune regulation in the COPD lung that may explain both the susceptibility to viral infection and the excessive inflammation associated with exacerbations.	26517304
Traumatic injury	Altered Intercellular Communication	Twenty-eight-day longitudinal HDAC leukocyte gene expression profiles in 172 blunt trauma patients were extracted from the Inflammation and the Host Response to Injury (Glue Grant) data set.	26517778
Waldenstrom Macroglobulinemia, Fibrosis Assessment	Altered Intercellular Communication	Histopathologic examination revealed marked lymphoplasmacytic inflammation and inter-lobular fibrosis, which were more severe in the superficial than deep portion of the affected glands.	26518180
N-formyl-13-dihydrocarminomycin, Inflammation	Altered Intercellular Communication	However, there are significant caveats associated with the idea that inflammation directly causes either a-synuclein pathology or neurofibrillary degeneration (NFD).	26518296
Inflammation	Altered Intercellular Communication	Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs.	26518879
deficiency aspects, Inflammation	Altered Intercellular Communication	Our data demonstrate for the first time that telomerase deficiency triggers alveolar stem cell replicative senescence-associated low-grade inflammation, thereby driving pulmonary premature aging, alveolar sac formation, and fibrotic lesion.	26518879
Inflammation, Data types - Address, physiopathological	Altered Intercellular Communication	Most processes associated with AD pathogenesis, such as inflammation, synaptic dysfunction, and hyper-phosphorylation of tau are dependent on protein kinase activity.	26519433
Inflammation, Acute-On-Chronic Liver Failure	Altered Intercellular Communication	Treatment with non-selective beta blockers is associated with reduced severity of systemic inflammation and improved survival of patients with acute-on-chronic liver failure.	26519600
Inflammation, Acute-On-Chronic Liver Failure, CRNKL1 wt Allele	Altered Intercellular Communication	Acute-on-chronic liver failure (ACLF) is characterized by systemic inflammation and high mortality.	26519600
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Haemodialysis patients suffer from chronic systemic inflammation and high incidence of cardiovascular disease.	26519693
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Prediabetes is associated with low-grade chronic inflammation that increases the risk for developing type 2 diabetes (T2D) and cardiovascular disease (CVD).	26520413
Inflammation, physiopathological	Altered Intercellular Communication	Selective modulation of the intestinal microbiota with prebiotics reduces intestinal permeability and endotoxin concentrations, inflammation, and metabolic dysfunction in rodents.	26520413
Tissue damage, Inflammation	Altered Intercellular Communication	Chemokines and cytokines play a pivotal role in the regulation of mucosal inflammation by promoting leukocyte migration to sites of inflammation ultimately leading to tissue damage and destruction.	26520877
Tissue damage, Gastrointestinal inflammation, Inflammatory Bowel Diseases	Altered Intercellular Communication	These data clearly indicate an increase in circulating levels of specific chemokines and cytokines that are known to modulate systemic level through immune cells results in affecting local intestinal inflammation and tissue damage in IBD patients.	26520877
Inflammation, Metabolic Syndrome X, Bipolar Disorder	Altered Intercellular Communication	Low physical activity, inflammation, metabolic syndrome and vascular risk factors were associated with elevated depressive symptoms.	26521086
Inflammation, Impaired cognition, Diabetes Mellitus, Bipolar Disorder, Hypertension, CTCAE	Altered Intercellular Communication	Low physical activity (z=2.16, p=0.03) and inflammation (z=2.3, p=0.02) mediated the relationship between depressive symptoms and cognitive decline while hypertension, diabetes and smoking also contributed.	26521086
Inflammation, Impaired cognition, Bipolar Disorder	Altered Intercellular Communication	The relationship between depressive symptoms and cognitive decline in later life appears to be mediated by low physical activity, increased inflammation and vascular risk factors that may be amenable to modification.	26521086
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	This study will help identify new therapeutic strategies for OA, especially the targeting of IL-22 to decrease inflammation.	26521730
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Associations of markers of matrix metabolism, inflammation markers, and adipokines with superior cam deformity of the hip and their relation with future hip osteoarthritis.	26521735
Rotator cuff syndrome, Inflammation, Congenital Abnormality	Altered Intercellular Communication	Some markers of inflammation (pLeptin, pAdiponectin, and erythrocyte sedimentation rate) were lower in presence of cam deformity and cam impingement, but high-sensitivity C-reactive protein was not.	26521735
Rotator cuff syndrome, Inflammation, Congenital Abnormality	Altered Intercellular Communication	Subjects with cam deformity and cam impingement surprisingly showed lower levels of inflammation markers and adipokines.	26521735
Degenerative polyarthritis, Inflammation, Erosion lesion	Altered Intercellular Communication	Ultrasound detected inflammation is associated with the development of new bone erosions in hand osteoarthritis: a longitudinal study over 3.9 years.	26521738
Degenerative polyarthritis, Inflammation, Erosion lesion, 4-hydroxy-2-oxovalerate aldolase activity	Altered Intercellular Communication	To evaluate the association between ultrasound (US) detected inflammation at baseline and the subsequent development of new bone erosions at follow-up in patients with hand osteoarthritis (HOA).	26521738
Inflammation	Altered Intercellular Communication	US detected synovial inflammation features were scored as present/absent.	26521738
Inflammation, Erosion lesion	Altered Intercellular Communication	Synovial inflammation as detected by PDS was associated with the appearance of new bone erosions.	26521738
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Inflammation plays a major role in OA, particularly through the cytokine Interleukine-1b, promoting reactive oxygen species (ROS) generation and matrix metalloproteinases (MMP) synthesis by the chondrocytes, orchestrating matrix proteolysis.	26521743
Inflammation	Altered Intercellular Communication	Taken together, we propose that SIRT1 forms an anti-inflammatory complex with HMGB1, allowing cells to bypass the response to inflammation.	26522327
Inflammation, Squamous cell carcinoma	Altered Intercellular Communication	The association and prognostic relevance of cancerous inhibitor of protein phosphatase 2A and inflammation in tongue squamous cell carcinoma.	26522733
Inflammation, Primary malignant neoplasm, Hyperplasia	Altered Intercellular Communication	CIP2A was similarly detected in tongue cancer and tongue hyperplasia, whereas local inflammation was stronger in cancer (p = 0.000).	26522733
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Cancer patients aged >=60 with increased inflammation predicted poor survival (p = 0.037).	26522733
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	CIP2A and inflammation might play a role in progression of tongue cancer.	26522733
Inflammation	Altered Intercellular Communication	Inflammation is a common link between metabolic dysregulation and aging.	26522807
allergic inflammation, Helminths	Altered Intercellular Communication	The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.	26522986
Synovitis, Edema, Erosion of bone, Orchitis, Tenosynovitis	Altered Intercellular Communication	Images were scored blindly twice by 3 independent readers according to the PsAMRIS (for synovitis, tenosynovitis, periarticular inflammation, bone edema, bone erosion, and bone proliferation).	26523032
Orchitis, Tenosynovitis	Altered Intercellular Communication	Baseline interreader ICC were good (ICC 0.72-0.96) for all features, except periarticular inflammation and bone proliferation in the hand and tenosynovitis in the foot (ICC 0.25-0.44).	26523032
Parkinson Disease, palladium, MULTISYSTEM DISORDER	Altered Intercellular Communication	Parkinson's disease (PD) is a multisystem disorder, involving several monoaminergic neurotransmitter systems resulting in a broad range of motor and non-motor symptoms.	26523794
Postprandial Period, Chylomicrons	Altered Intercellular Communication	In vivo evidence for chylomicrons as mediators of postprandial inflammation.	26523991
Postprandial Period	Altered Intercellular Communication	The postprandial chylomicron response may be a stronger mediator of postprandial inflammation than postprandial triglyceridemia.	26523991
Atherosclerosis	Altered Intercellular Communication	The postprandial situation is a pro-inflammatory condition most likely linked to the development of atherosclerosis.	26523991
Inflammation, Asthma, AHR wt Allele	Altered Intercellular Communication	This study aims to determine whether in utero ETS exposure alters DNA methylation patterns and increases airway hyperreactivity (AHR) and inflammation.	26525176
AHR wt Allele, Pneumonitis	Altered Intercellular Communication	Collectively, these data suggest that in utero ETS exposure increases the risk of pulmonary inflammation and AHR through altered DNA methylation, but additional studies are needed to fully determine the causal link between changes in methylation and cytokines levels, as well as AHR.	26525176
Inflammation	Altered Intercellular Communication	Post-cardiac arrest syndrome (PCAS) is characterized by systemic inflammation, however data on the prognostic value of inflammatory markers is sparse.	26525271
Cardiac Arrest, Inflammation, Comatose	Altered Intercellular Communication	We sought to investigate the importance of systemic inflammation, assessed by interleukin-6 (IL-6) in comatose survivors of out-of-hospital cardiac arrest.	26525271
Inflammation, Injury wounds, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Increased expression of TLR9 associated with pro-inflammatory S100A8 and IL-8 in diabetic wounds could lead to unresolved inflammation in type 2 diabetes mellitus (T2DM) cases with impaired wound healing.	26525587
Inflammation, Ulcer	Altered Intercellular Communication	Immune dys-regulation is the hallmark of T2DM that could contribute to prolonged inflammation causing transformation of wounds into non-healing chronic ulcers.	26525587
Inflammation	Altered Intercellular Communication	We hypothesized that pro-inflammatory S100A8 and IL-8 proteins could cause persistent inflammation in chronic wounds like diabetic foot ulcer (DFU) and may contribute to impaired wound healing in T2DM patients.	26525587
ARCN1 gene, Bacterial Infections, Airway structure	Altered Intercellular Communication	Smoking-induced COPD is characterized by chronic airway inflammation, which becomes enhanced by bacterial infections resulting in accelerated disease progression called exacerbation.	26526351
Inflammation, Progranulins, Subarachnoid Hemorrhage	Altered Intercellular Communication	Decreased progranulin levels in patients and rats with subarachnoid hemorrhage: a potential role in inhibiting inflammation by suppressing neutrophil recruitment.	26527034
Progranulins, GRN wt Allele	Altered Intercellular Communication	Progranulin (PGRN) is known to be involved in various biological functions, such as anti-inflammation and tissue repair.	26527034
Inflammation, Asthma	Altered Intercellular Communication	We demonstrate that eosinophil-dominant inflammation starts in ethmoidal sinus clinicopathogenetically in CRS with asthma.	26527517
Inflammatory abnormality of the eye	Altered Intercellular Communication	Quantifying Ocular Surface Inflammation and Correlating It With Inflammatory Cell Infiltration In Vivo: A Novel Method.	26529042
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	C-reactive protein (CRP), an acute phase protein synthesized primarily in the liver, is a marker for inflammation and for the progression of many cancers.	26529498
Hemangioma, Cavernous	Altered Intercellular Communication	[Granulomatous inflammation in the bed of resected cerebral cavernoma in a child, caused by a hemostatic agent].	26529626
Granuloma, Hemangioma, Cavernous, Inflammation	Altered Intercellular Communication	The study presents a clinical observation of foreign body granuloma, which is rare productive inflammation, developed on treatment with a hemostatic material upon removal of cerebral cavernoma.	26529626
Inflammation, Granuloma	Altered Intercellular Communication	Inflammation was accompanied by the formation of foreign body granulomas, and, in some areas, had immune nature with signs of focal destructive vasculitis, delayed maturation of the granulation tissue, and disturbance of the current organization and encapsulation processes.	26529626
Granulomatous inflammation, Neoplasms	Altered Intercellular Communication	It is worth noting that granulomatous inflammation around a hemostatic material in the brain has no specific features during introscopy and mimics an abscess or tumor recurrence.	26529626
Granulomatous inflammation	Altered Intercellular Communication	To prevent granulomatous inflammation, removal of a hemostatic material, if possible, from the surgical field is recommended when reliable hemostasis is achieved.	26529626
Inflammation, Muscle of pelvic diaphragm, Bacterial Infections, Brain Damage, Chronic	Altered Intercellular Communication	Pelvic floor muscle abnormalities, altered neuroendocrine pathways, chemically induced inflammation, bacterial infection, autoimmune processes, dysfunctional voiding as well intraprostatic ductal reflux mechanisms have all been identified in men with chronic pelvic pain syndrome.	26529825
Trachoma	Altered Intercellular Communication	The overall prevalence of active trachoma among children aged 1-9 years were 23.1 % (Trachomatous inflammation-Follicular, in 22.5 % (95 % CI: 22.3-22.69 %); Trachomatous inflammation-Intense, in 0.6 % (95 % CI: 0.4-0.79 %).	26530131
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Signs of immune activation and local inflammation are present in the bronchial tissue of patients with untreated early rheumatoid arthritis.	26530319
Primary malignant neoplasm	Altered Intercellular Communication	The Glasgow Prognostic Score (GPS), calculated from the serum levels of CRP and albumin, is well known to be a valuable inflammation-based prognostic system for several types of cancer.	26530445
Colorectal Carcinoma	Altered Intercellular Communication	CAR is as useful for predicting the postoperative survival of patients with CRC as previously reported inflammation-based prognostic systems, such as GPS and NLR.	26530445
Hereditary Autoinflammatory Diseases, Inflammation, NLRP3 gene	Altered Intercellular Communication	Muckle-Wells-syndrome (MWS) is an autoinflammatory disease characterized by systemic and organ-specific inflammation due to excessive interleukin (IL)-1 release.	26531310
Inflammation, Sensorineural Hearing Loss (disorder)	Altered Intercellular Communication	Inner ear inflammation results in irreversible sensorineural hearing loss, if untreated.	26531310
Inflammation, NLRP3 gene	Altered Intercellular Communication	Early inner ear inflammation in MWS primarily affects the high frequencies, beyond the range of standard otologic assessment tools.	26531310
Intraocular inflammation, Hemorrhagic	Altered Intercellular Communication	Examination disclosed intraocular inflammation, along with plain white peripheral non-exudative lesions with sparse haemorrhaging.	26531739
Inflammation, Atherosclerosis, Cardiovascular Diseases, Endothelial dysfunction, Ischemic stroke	Altered Intercellular Communication	Chronic inflammation that triggers endothelial dysfunction and atherosclerosis may promote the evolution of cardiovascular diseases, including acute ischemic stroke (AIS).	26534741
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	We hypothesized that air pollution, an inflammation progenitor, can be associated with stroke incidence in young patients in whom the usual risk factors for stroke are less prevalent.	26534971
Inflammation	Altered Intercellular Communication	The inflammation results from the phagocytosis of monosodium urate crystals (MSU) and the release of inflammatory cytokines within the joint.	26535601
Inflammation	Altered Intercellular Communication	A biopsy identified chronic inflammation of the mucosa and tissue.	26535832
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Fecal calprotectin is a reliable noninvasive marker for intestinal inflammation usable for monitoring patients with inflammatory bowel disease.	26535869
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	The CalproSmart test performed by patients with inflammatory bowel disease for fast assessment of gut inflammation seems a reliable alternative to ELISA and presents a new way of monitoring patients by eHealth.	26535869
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	CCL20 and CCR6 mRNA abundances were increased during active inflammation (CCL20 5.4-fold in ulcerative colitis and 4.2-fold in Crohn's disease; CCR6 1.8 and 2.0, respectively).	26536229
Inflammation	Altered Intercellular Communication	CCL20 and CCR6 mRNA positive immune cells in lamina propria were more numerous, and CCL20 immunoreactivity increased massively in the epithelial cells during active inflammation for both diseases.	26536229
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	The CCL20-CCR6 axis is involved during active inflammation in both ulcerative colitis and Crohn's disease.	26536229
Inflammation, Rupture, Periodontal Diseases, Dental Plaque, Periodontal Ligament	Altered Intercellular Communication	Periodontal disease has been associated with cardio- and cerebrovascular events, and inflammation in the periodontium is suggested to increase the systemic inflammatory level of the host, which may in turn influence plaque composition and rupture.	26536303
Inflammatory abnormality of the eye	Altered Intercellular Communication	Visual acuity and ocular inflammation scores before and 6 months after surgery were compared.	26536452
Inflammation, Uveitis	Altered Intercellular Communication	In granulomatous uveitis, the mean inflammation scores decreased significantly both in the anterior segment and in the posterior segment.	26536452
Inflammation, Uveitis	Altered Intercellular Communication	In nongranulomatous uveitis, the mean inflammation score in the posterior segment decreased significantly, although it did not change in the anterior segment.	26536452
ARCN1 gene, Communicable Diseases, Tooth Loss, Inflammation	Altered Intercellular Communication	An increased understanding of causal mechanisms linking cigarette smoking, oral health, and COPD, particularly the role of tooth loss, infection, and subsequent inflammation, is essential to reduce the burden of COPD.	26537367
Inflammation, Hemorrhage, Trauma, Nervous System, Seizures, Cessation of life	Altered Intercellular Communication	The iCKO mice developed severe seizures accompanied by neuronal injury, multiple brain petechial hemorrhages, and central nervous system inflammation, and all had postictal death.	26538583
Seizures, Inflammation, physiopathological, Brain hemorrhage	Altered Intercellular Communication	The results suggest that BBB dysfunction secondary to defective b-catenin transcription activity is a key pathogenic factor in hemorrhagic stroke, seizure activity, and central nervous system inflammation.	26538583
Inflammation, Fibrosis Assessment, Hepatitis, Liver Dysfunction	Altered Intercellular Communication	For any degree of fibrosis, >= moderate inflammation on histology or HCV hepatitis accompanying with abnormal liver function, we treated with pegylated interferon and ribavirin.	26539000
Mediastinitis	Altered Intercellular Communication	Esophageal reconstruction was performed after controlling the mediastinal inflammation.	26539019
Aneurysm	Altered Intercellular Communication	Activation of Endocannabinoid System Is Associated with Persistent Inflammation in Human Aortic Aneurysm.	26539497
Inflammation, Aortic Aneurysm	Altered Intercellular Communication	Human aortic aneurysms have been associated with inflammation and vascular remodeling.	26539497
Inflammation, Aortic Aneurysm	Altered Intercellular Communication	Since the endocannabinoid system modulates inflammation and tissue remodeling, we investigated its components in human aortic aneurysms.	26539497
Inflammation, Aortic Aneurysm	Altered Intercellular Communication	Our data provides evidence for endocannabinoid system activation in human aortic aneurysms, associated with persistent low-level inflammation and vascular remodeling.	26539497
Inflammation	Altered Intercellular Communication	Hepcidin and neutrophil-gelatinase associated lipocalin (NGAL) are induced by inflammation and these proteins may take role in ESA resistance.	26539647
Inflammation, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	Interleukin-17A Is Associated With Alveolar Inflammation and Poor Outcomes in Acute Respiratory Distress Syndrome.	26540401
Inflammation, Lung Injury	Altered Intercellular Communication	Interleukin-17A is a proinflammatory cytokine known to play a role in host defense and pathologic inflammation in murine models of lung injury.	26540401
Inflammation, Lung Injury	Altered Intercellular Communication	The relationship between interleukin-17A and inflammation in human lung injury is unknown.	26540401
Respiratory Distress Syndrome, Adult, Inflammation, Traumatic injury	Altered Intercellular Communication	Our primary objective was to determine whether interleukin-17A levels are associated with alveolar measures of inflammation and injury in patients with acute respiratory distress syndrome.	26540401
Peripheral Vascular Diseases, Inflammation, Myocardial Ischemia, Malignant Neoplasms	Altered Intercellular Communication	Neutrophil-lymphocyte ratio (NLR) is a marker of systemic inflammation that has been shown to predict mortality in patients with malignancies, ischemic heart disease and peripheral vascular disease.	26540580
Inflammation, AATF wt Allele	Altered Intercellular Communication	These changes, which reflect the degree of immune activation and inflammation in DED, can be used for clinical practice and endpoints in clinical trials.	26540656
Degenerative polyarthritis, Inflammation, physiopathological	Altered Intercellular Communication	However, there is no scientific evidence that regular swimming reduces vascular dysfunction and inflammation and elicits similar benefits compared with land-based exercises such as cycling in terms of reducing vascular dysfunction and inflammation in patients with OA.	26541906
Common Variable Immunodeficiency	Altered Intercellular Communication	Common variable immunodeficiency (CVID) is an antibody deficiency treated with immunoglobulin; however, patients can have noninfectious inflammatory conditions that lead to heightened morbidity and mortality.	26542033
Inflammation, Fibrosis Assessment, Neuronal loss in central nervous system	Altered Intercellular Communication	Pathology specimens were graded on degree of neuronal loss, inflammation, fibrosis, and muscle changes.	26542087
Inflammation, Fibrosis Assessment, Muscular Atrophy	Altered Intercellular Communication	On histopathology, complete ganglion cell loss occurred in 74% of specimens, inflammation in 17%, fibrosis in 11%, and muscle atrophy in 2%.	26542087
Achalasia, Inflammation, Pyloric Stenosis, Neuronal loss in central nervous system	Altered Intercellular Communication	The spectrum of histopathologic findings - from complete neuronal loss to lymphocytic inflammation to apparently normal histopathology - emphasizes that 'achalasia' represents a pathogenically heterogeneous patient group with the commonality being EGJ outflow obstruction.	26542087
Chronic disease	Altered Intercellular Communication	Increased oxidative stress (OS) has been implicated in a variety of chronic diseases, inflammatory conditions, aging, and even following intense physical exercise.	26542596
Inflammation, Thrombophilia	Altered Intercellular Communication	Correlation of Inflammation and Lipoprotein (a) with Hypercoagulability in Hemodialysis Patients.	26543308
Inflammation, ciliary vesicle	Altered Intercellular Communication	Classical CV disease risk factors were recorded and systemic inflammation was determined by the measurement of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR).	26543327
Inflammation, Necrosis	Altered Intercellular Communication	Pathological assessment of necrosis, inflammation and proliferation index was also performed.	26544728
Inflammation, Mesothelioma, Necrosis	Altered Intercellular Communication	Sarcomatoid/biphasic and epithelioid mesotheliomas showed different MDM2 and HIF1alpha expression levels and were characterized by different levels of necrosis, proliferation and inflammation.	26544728
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The neutrophil-to-lymphocyte ratio (NLR) is considered an indicator of systemic inflammation and may predict prognosis in colorectal cancer.	26544755
Inflammation, Spinal Cord Injuries	Altered Intercellular Communication	Targeting inflammation to influence mood following spinal cord injury: a randomized clinical trial.	26545369
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Due to the limited sample size, results should be interpreted with caution; however, they are worthy of further examination due to the potential impact of inflammation on depression.	26545369
Weight Gain	Altered Intercellular Communication	the hormonal decline that is characteristic of the menopause, in conjunction with the associated weight gain, is considered a determinant factor of cardiovascular risk.	26545524
Esophageal and Gastric Varices, Duodenal inflammation	Altered Intercellular Communication	Esophageal, gastric, and duodenal inflammation were detected in 21%, 74%, and 37% of patients, respectively.	26545803
Inflammation	Altered Intercellular Communication	Interleukin (IL)-17 has been shown to play an important role in tissue inflammation and in the pathogenesis of immune-related liver damage.	26546176
Inflammation, Heart failure	Altered Intercellular Communication	Patients with heart failure (HF) have evidence of chronic systemic inflammation.	26546248
Inflammation, hafnium, Impaired exercise tolerance	Altered Intercellular Communication	Whether inflammation contributes to the exercise intolerance in patients with HF is, however, not well established.	26546248
Inflammation, Myocardial Ischemia	Altered Intercellular Communication	In conclusion, the intensity of systemic inflammation, measured as CRP plasma levels, is associated with cardiopulmonary exercise performance, in patients with ischemic heart disease and chronic systolic HF.	26546248
Communicable Diseases, Chronic pulmonary aspergillosis, Inflammation	Altered Intercellular Communication	Response to vaccination has not been studied in chronic lung conditions characterised by ongoing infection or inflammation like chronic pulmonary aspergillosis (CPA).	26546263
Small cell carcinoma of lung, Inflammation, Sarcopenia	Altered Intercellular Communication	Sarcopenia and inflammation are independent predictors of survival in male patients newly diagnosed with small cell lung cancer.	26546456
Inflammation, Sarcopenia	Altered Intercellular Communication	Sarcopenia is suggested to be associated with cancer-related inflammation.	26546456
HD Term Type, Hypokinesia	Altered Intercellular Communication	These results identify impairment of cortico-striatal synaptic transmission and dopamine release as a potential basis of hypokinesia in HD.	26546830
Nasopharyngitis, Diarrhea, Folliculitis	Altered Intercellular Communication	The most common AE in the brodalumab groups were nasopharyngitis (12.4% vs. 7.9% for placebo), diarrhea (5.3% vs. 0%), upper respiratory tract inflammation (3.5% vs. 0%), and folliculitis (3.5% vs. 0%).	26547109
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Chronic inflammation increases the risk of development of human malignancies.	26547585
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	GlycA is a recently developed glycoprotein biomarker of systemic inflammation that may be predictive of incident type 2 diabetes mellitus (T2DM).	26549655
Inflammation, Infectious Lung Disorder, Pulmonary Valve Insufficiency, Cystic Fibrosis	Altered Intercellular Communication	After repeated cycles of lung infection and inflammation, patients with cystic fibrosis (CF) evolve to respiratory insufficiency.	26551917
Inflammation, Aortitis, Granuloma	Altered Intercellular Communication	The final diagnosis of tuberculous aortitis was made on the basis of macroscopic appearance of inflammation and microscopic confirmation of caseating granuloma.	26553119
Inflammation, Asthma	Altered Intercellular Communication	The ADAM family is involved in some pathologic processes, such as inflammation and asthma.	26553447
Degenerative polyarthritis, Pain Distress Question	Altered Intercellular Communication	Association of Joint Inflammation With Pain Sensitization in Knee Osteoarthritis: The Multicenter Osteoarthritis Study.	26554395
Degenerative polyarthritis, Inflammation, Bone Marrow, Synovitis	Altered Intercellular Communication	We examined whether inflammation, assessed as synovitis and effusion on magnetic resonance imaging (MRI), or mechanical load, assessed as bone marrow lesions (BMLs), was associated with sensitization in knee OA.	26554395
Inflammation, Pain Distress Question, Synovitis, Degenerative polyarthritis, effusion	Altered Intercellular Communication	Inflammation, as evidenced by synovitis or effusion, is associated with pain sensitization in knee OA.	26554395
Degenerative polyarthritis, Inflammation, Pain Distress Question	Altered Intercellular Communication	Early targeting of inflammation is a reasonable strategy to test for prevention of sensitization and through this, reduction of pain severity, in knee OA.	26554395
Hepatic inflammation, Hepatitis B, Chronic	Altered Intercellular Communication	The macrophage activation marker CD163 is associated with IL28B genotype and hepatic inflammation in chronic hepatitis C virus infected patients.	26554542
Communicable Diseases, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Recent data highlighted the association of the macrophage activation marker CD163 with histological inflammation and fibrosis in chronic hepatitis C virus (HCV) infection.	26554542
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In the multivariate logistic regression analyses, sCD163 was independently associated with histologically determined inflammation (P = 0.043) but not with fibrosis (P = 0.091).	26554542
Inflammation, Clear-cell metastatic renal cell carcinoma	Altered Intercellular Communication	Interleukin-6 (IL-6) is the major cytokine that induces transcriptional acute and chronic inflammation responses, and was recently incorporated as a recurrence prognostication signature for localised clear-cell renal cell carcinoma (ccRCC).	26554658
Inflammation	Altered Intercellular Communication	As pelvic enthesitis indicates active inflammation, it may play a role in assessment of the inflammatory status.	26554668
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation and hemostasis contribute to the etiology of cardiovascular disease.	26554758
Juvenile arthritis, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	The purpose of this study was to investigate the presence of bacterial DNA in synovial fluid, and to compare this with clinical and immunological findings in children with JIA, adults with persistent JIA, and adults with rheumatoid arthritis, in order to detect whether bacteria contribute to inflammation in TMJ arthritis.	26554824
Inflammation	Altered Intercellular Communication	Finally, global knee inflammation (GKI) for each knee joint was calculated as the sum of cMVP mean in all segmented regions.	26555103
Inflammation, Degenerative disorder	Altered Intercellular Communication	As degenerative disease is age-related and inflammation is implicated in its pathogenesis, our findings further support this association.	26555103
Inflammation, Arthropathy	Altered Intercellular Communication	These preliminary data suggest that this approach can potentially provide a means to objectively quantify the degree of inflammation in various joint disorders, and possibly in other knee degenerative/inflammatory diseases.	26555103
Inflammation	Altered Intercellular Communication	Moreover, the possible causal relationship between calcifying vascular smooth muscle cells and inflammation was explored in vitro.	26555788
Inflammation, Calcinosis	Altered Intercellular Communication	In vitro experiments using human vascular smooth muscle cells (hVSMCs) were performed to evaluate causal relationships between calcification and inflammation.	26555788
Inflammation, Calcinosis, Failure (biologic function)	Altered Intercellular Communication	Our findings suggest that loss of calcification inhibitors and/or failure of inhibitory capacity is causative for the early precipitation of calcium, with concomitant increased inflammation followed by osteochondrogenic transdifferentiation of VSMCs.	26555788
Inflammation, De Quervain Disease	Altered Intercellular Communication	The greater the levels of ER-b expression, tissue inflammation, and angiogenesis are, the more severe de Quervain's disease is.	26556342
Malignant neoplasm of liver, Inflammation, FAM126A gene	Altered Intercellular Communication	Inflammation and diet have been suggested to be important risk factors for hepatocellular cancer (HCC).	26556602
Refractory anemias, Inflammation	Altered Intercellular Communication	The amelioration of inflammation, particularly via IL-17 antagonism, might be a new therapeutic approach for enhancing intrinsic cartilage repair mechanisms in RA patients.	26558442
Inflammation, Non-cirrhotic	Altered Intercellular Communication	Lobular inflammation was present in 63.6 % of non-cirrhotic patients.	26558795
Helicobacter pylori, Gastritis	Altered Intercellular Communication	Helicobacter pylori (H. pylori) -induced gastric inflammation impacts the functions of leptin- and ghrelin-producing cells in the gastroduodenum.	26559190
Inflammation, Primary malignant neoplasm, Blood Vessel	Altered Intercellular Communication	Cancer and its treatment may affect cognitive function through a number of direct and indirect pathways including inflammation, lipid metabolism, vascular damage, and changes in the blood-brain barrier.	26559193
Inflammation, Neoplasms	Altered Intercellular Communication	Increasing emphasis is put on the concept that inflammation is a key player in tumor progression.	26560001
Follicular conjunctivitis, Pseudolymphoma	Altered Intercellular Communication	When a chronic follicular conjunctivitis is refractory to treatment, it is essential to perform an incisional biopsy to establish the histopathological diagnosis that can range from chronic inflammation, reactive lymphoid hyperplasia to lymphoma.	26560164
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	The metabolic syndrome (MetS) is associated with a chronic low-grade inflammatory state and may be affected by the ability to resolve inflammation, which is an active process that involves specialized proresolving lipid mediators (SPMs) derived from n-3 (o-3) fatty acids.	26561623
Malignant neoplasm of liver, Inflammation, Primary malignant neoplasm, Liver damage	Altered Intercellular Communication	The association of coffee intake with liver cancer risk is mediated by biomarkers of inflammation and hepatocellular injury: data from the European Prospective Investigation into Cancer and Nutrition.	26561631
Inflammation, Liver damage, FAM126A gene	Altered Intercellular Communication	These data suggest that the inverse association of coffee intake with HCC risk was partly accounted for by biomarkers of inflammation and hepatocellular injury.	26561631
Inflammation, Liver neoplasms	Altered Intercellular Communication	Exposure to fine particulate matter (PM2.5) may promote hepatic tumorgenesis through low-grade inflammation.	26561636
Malignant neoplasm of liver, Hepatitis	Altered Intercellular Communication	Long-term PM2.5 exposure increased the risk for liver cancer, and chronic inflammation of the liver may underlie the pathogenesis.	26561636
Fibrillation, Inflammation, Myopathy, Myositis	Altered Intercellular Communication	Electromyography revealed myopathy with fibrillation potentials; 78% of biopsies had active necrotizing myopathy with minimal inflammation, and 17% had inflammatory myopathy.	26561982
Intraocular inflammation, Unknown (origin) (qualifier value), Dermatitis, Atopic, Data types - Address, Congenital MeSH qualifier, Traumatic injury, Myopia	Altered Intercellular Communication	The most common aetiology for RRD was idiopathic (28.6%), followed by high myopia (24.5%), atopic dermatitis (AD) (18.4%), congenital and developmental abnormalities (16.3%), trauma (8.2%), and intraocular inflammation (4.1%).	26563656
Inflammation, Anemia	Altered Intercellular Communication	Therefore, we examined the association between frailty and a range of serum markers on inflammation, anaemia, the metabolic system, micronutrients and renal functioning.	26563885
Inflammation, Anemia	Altered Intercellular Communication	Frailty appears associated with inflammation (IL-6 and CRP), anaemia, metabolic markers (glucose, cholesterol and albumin) and renal functioning (cystatin-C and creatinine).	26563885
Inflammation, Dental Plaque	Altered Intercellular Communication	We hypothesised that patients with unstable carotid plaque have higher levels of circulating microparticles compared to patients with stable plaques, and may correlate with serum markers of plaque instability and inflammation.	26564003
Renal Insufficiency, Inflammation, Cognition Disorders, Data types - Address	Altered Intercellular Communication	J147 reduced cognitive deficits in old SAMP8 mice, while restoring multiple molecular markers associated with human AD, vascular pathology, impaired synaptic function, and inflammation to those approaching the young phenotype.	26564964
Inflammatory Bowel Diseases	Altered Intercellular Communication	Taken together, our GWAS-based analysis and in vitro and in vivo studies have demonstrated that Nur77 is an important regulator of TRAF6/TLR-IL-1R-initiated inflammatory signalling, and loss of Nur77 may contribute to the development of IBD, suggesting Nur77 as a potential target for the prevention and treatment of IBD.	26564988
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Metabolic syndrome (MetS) has been identified to be associated with a state of chronic, low-grade inflammation in adipose tissue.	26565966
Hyperglycemia, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Type 2 diabetes and critical illness have phenotypical similarities, such as hyperglycaemia, insulin resistance and systemic inflammation.	26567860
Thrombotic Microangiopathies, Inflammation, Breast Carcinoma	Altered Intercellular Communication	The Potential Role of Inflammation Associated with Interaction between Osteopontin and CD44 in a Case of Pulmonary Tumor Thrombotic Microangiopathy Caused by Breast Cancer.	26568002
Inflammation	Altered Intercellular Communication	These findings suggest that inflammation associated with the interaction between osteopontin and CD44 may play an important role in PTTM.	26568002
Inflammation, Specimen Source Codes - Abscess	Altered Intercellular Communication	Recovery was uneventful until he experienced inflammation of the groin, and required open drainage three times for a refractory abscess in his right groin.	26568391
Inflammation	Altered Intercellular Communication	The mesh was successfully removed under general anesthesia, and the inflammation in the groin resolved.	26568391
Inflammation, Metabolic Diseases, Hyperuricemia, Gout	Altered Intercellular Communication	Gout is a common metabolic disorder characterized by hyperuricemia and chronic inflammation.	26568484
Inflammation	Altered Intercellular Communication	Inflammation, Oxidative Stress, and Antioxidants Contribute to Selected Sleep Quality and Cardiometabolic Health Relationships: A Cross-Sectional Study.	26568665
Inflammation	Altered Intercellular Communication	Our results provide initial evidence of a potential role for inflammation, oxidative stress, and antioxidants in the pathway between poor sleep quality-cardiometabolic decline.	26568665
Carcinoma of bladder	Altered Intercellular Communication	Predictive value of pretreatment inflammation-based prognostic scores (neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and lymphocyte-to-monocyte ratio) for invasive bladder carcinoma.	26568792
Inflammation	Altered Intercellular Communication	Psychological distress may contribute to chronic activation of acute-phase inflammation.	26569541
Inflammation, Colorectal Carcinoma, Ulcerative Colitis	Altered Intercellular Communication	Prolonged inflammation of colon in UC patients increases the risk of developing colorectal cancer.	26569605
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	MiRNA are reported as a connecting link between inflammation and cancer.	26569605
Airway structure, Asthma, Bronchial Hyperreactivity	Altered Intercellular Communication	The pathophysiology of asthma is multifaceted, and is characterized by restriction of airflow into and out of the lungs, airway inflammation with increased mucus production, and bronchial hyper-reactivity caused by exposure to environmental irritants and chemicals, often referred to as triggers, which in some cases are modifiable.	26571284
Hyperuricemia	Altered Intercellular Communication	Lowering Uric Acid With Allopurinol Improves Insulin Resistance and Systemic Inflammation in Asymptomatic Hyperuricemia.	26571421
Inflammation, Hyperuricemia	Altered Intercellular Communication	Allopurinol lowers uric acid and improves insulin resistance and systemic inflammation in asymptomatic hyperuricemia.	26571421
TNF protein, human, Tumor necrosis, Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Tumor necrosis factor-alpha (TNF-a) contributes in inflammation and has been implicated in the development of colorectal cancer (CRC).	26572151
Inflammation	Altered Intercellular Communication	Recent advances have highlighted the essential role of inflammation in the development of the disease.	26572732
Inflammation, Failure, Angular, Data types - Address	Altered Intercellular Communication	Multiple genes and molecular mechanisms have been implicated in AD, including ss-amyloid deposition in the brain, neurofibrillary tangle accumulation of hyper-phosphorylated Tau, synaptic failure, oxidative stress and inflammation.	26573292
Airway structure, Allergic asthma	Altered Intercellular Communication	Accordingly, knockdown of CCR2 in UCB-MSCs significantly improved their therapeutic ability to alleviate airway inflammation in an experimental allergic asthma model.	26573462
Peripheral arterial occlusive disease, Inflammation, Ulcer	Altered Intercellular Communication	For PEDIS single criteria, significantly lower overall complication rates were found for patients without signs of occlusive peripheral artery disease, an ulcer extent <0.9 cm(2), ulcer depth including erosion and inflammation of the skin and subcutaneous tissues only.	26573860
Inflammation	Altered Intercellular Communication	Inflammation and oxidative stress improved significantly in the liraglutide group compared to the placebo group.	26573925
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Fibrosis was more frequently classified as inflammation with MR-E compared with PET/MR-E [p = 0.019].	26574490
Inflammation, Atherosclerosis	Altered Intercellular Communication	Associations Between Cardiovascular Risk Factors, Inflammation, and Progression of Carotid Atherosclerosis Among Smokers.	26574552
Inflammation	Altered Intercellular Communication	It also stimulates cell migration and structural support, provides moisture environment, decreases inflammation, and induces cell proliferation and cellular attachments.	26574754
Heredity, Inflammation, contagion	Altered Intercellular Communication	Ninety-six percent of the patients believed that there were also medical causes (such as an illness, brain insult, inflammation, heredity, contagion), and a similar proportion believed that there were also religious causes.	26575254
Inflammation, Insemination, Artificial, Homologous	Altered Intercellular Communication	By contrast, levels of circulating miR-21 showed a significant correlation with the histological grades of inflammation in AIH.	26575387
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, physiopathological, Bipolar Disorder	Altered Intercellular Communication	Elucidating the Biological Mechanisms Linking Depressive Symptoms With Type 2 Diabetes in Men: The Longitudinal Effects of Inflammation, Microvascular Dysfunction, and Testosterone.	26575859
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, physiopathological, Bipolar Disorder	Altered Intercellular Communication	This prospective cohort study sought to examine key biological measures linking depressive symptoms with Type 2 diabetes, specifically inflammation, microvascular dysfunction, and androgens.	26575859
Craniocerebral Trauma, Cognition Disorders	Altered Intercellular Communication	A single-nucleotide polymorphism in catechol-o-methyltransferase (COMT), an enzyme which degrades catecholamine neurotransmitters, may influence cognitive deficits following moderate and/or severe head trauma.	26576546
Macular Edema, Cystoid, Vitreous inflammatory cells	Altered Intercellular Communication	Best-corrected visual acuity (VA), complications, resolution of cystoid macular edema (CME), and anterior chamber and vitreous inflammation were assessed.	26576712
Vitreous inflammatory cells	Altered Intercellular Communication	There were no significant differences in baseline VA, anterior chamber and vitreous inflammation, presence of CME, and prior use of regional corticosteroid injections.	26576712
Inflammation	Altered Intercellular Communication	T cell inflammation plays pivotal roles in obesity-associated type 2 diabetes (T2DM).	26576827
Inflammation	Altered Intercellular Communication	The identification of dominant sources of T cell inflammation in humans remains a significant gap in understanding disease pathogenesis.	26576827
Inflammation	Altered Intercellular Communication	It was hypothesized that cytokine profiles from circulating T cells identify T cell subsets and T cell cytokines that define T2DM-associated inflammation.	26576827
Inflammation	Altered Intercellular Communication	Multivariate analyses indicated that B cells support Th17 inflammation in T2DM but not control samples, while monocytes supported Th17 inflammation regardless of T2DM status.	26576827
Inflammation, Hyperglycemia	Altered Intercellular Communication	Among various T cell subsets, Th17 cells are major contributors to inflammation and hyperglycemia and are uniquely supported by B cells in obesity-associated T2DM.	26576827
Mycosis Fungoides, Inflammation	Altered Intercellular Communication	Mycosis fungoides (MF) and parapsoriasis display increased inflammation, which may be associated with increased risk of arterial cardiovascular events.	26576854
Malabsorption Syndrome, physiopathological, Growth Disorders	Altered Intercellular Communication	Environmental enteric dysfunction (EED), a pervasive chronic subclinical inflammatory condition among children that develops when complementary foods are introduced, places them at high risk of stunting, malabsorption, and poor oral vaccine efficacy.	26578308
Granulomatosis, Scleritis, Sudden Visual Loss, Orbital Pseudotumor, Vasculitis, Systemic Vasculitis	Altered Intercellular Communication	A 24-year-old woman with a clinical history of granulomatosis with polyangiitis who presented with acute vision loss was found to have frosted branch angiitis with concurrent posterior scleritis and orbital inflammation.	26579594
MTA2 gene, Inflammation, Chronic pelvic pain of female, Pelvic Inflammatory Disease	Altered Intercellular Communication	Pelvic inflammatory disease (PID) has been investigated in Western countries and identified to be associated with chronic pelvic pain and inflammation.	26579800
Inflammation, Pelvic Pain	Altered Intercellular Communication	Chronic pelvic pain is a main symptom of BPS/IC, and chronic inflammation is a major etiology of BPS/IC.	26579800
Inflammation	Altered Intercellular Communication	KLIP should not be considered a variant of classical KFD, but rather as an elementary pattern of cutaneous inflammation, that might be the expression of the same cytotoxic process within skin infiltrates as that involved in KFD.	26579818
Critical Illness	Altered Intercellular Communication	In critically ill mechanically ventilated patients, in whom microbial colonization of the upper airways is constant, collection of aEBC could considerably add to the ability of monitoring alveolar inflammation.	26581173
Inflammation, Fibrosis Assessment, Leucocytic infiltrate	Altered Intercellular Communication	In sub-acute phase, 18F-fluorodeoxyglucose positron emission tomography showed no evidence of inflammation, and repeat EMB showed a significant decrease in the inflammatory infiltration and fibrosis, including absence of giant cells.	26581394
Chagas Disease, Myocarditis	Altered Intercellular Communication	On pathology Chagas' heart disease is characterized by chronic myocardial inflammation and extensive myocardial fibrosis.	26581396
Colorectal Carcinoma	Altered Intercellular Communication	A typical inflammation-related CRC mouse model was generated using azoxymethane-dextran sodium sulfate (AOM-DSS), and TIFs were collected from these mice in four stages during CRC development.	26581642
Inflammation, Primary malignant neoplasm, Cardiovascular Diseases, Depression, CTCAE, Asthma	Altered Intercellular Communication	Stress is strongly associated with several mental and physical health problems that involve inflammation, including asthma, cardiovascular disease, certain types of cancer, and depression.	26581830
Inflammation, SDSL gene	Altered Intercellular Communication	It is believed that aberrant angiogenesis and intracapsular inflammation contribute to the development of CSDH.	26581842
Chronic lymphocytic inflammation, Pontine structure, Hepatitis B, Clippers	Altered Intercellular Communication	Chronic hepatitis B infection presenting with chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS): a case report.	26582039
Brain Stem, Diplopia, Pontine structure, Dysarthria, CTCAE, Facial paralysis, Chronic lymphocytic inflammation, Cerebellar Ataxia	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids is a brainstem disorder characterized by perivascular pathologic reaction with lymphocyte infiltration and leading to diplopia, facial palsy, dysarthria, and gait ataxia.	26582039
Chronic lymphocytic inflammation, Pontine structure, Hepatitis B, Chronic	Altered Intercellular Communication	Patients with chronic hepatitis B infection may develop the syndrome of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids.	26582039
Chronic lymphocytic inflammation, Pontine structure, Hepatitis B	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids was diagnosed, with increased hepatitis B viral load at the same time.	26582039
Chronic lymphocytic inflammation, Pontine structure, Hepatitis B	Altered Intercellular Communication	Hepatitis B virus infection may induce central nervous system autoimmune reactions, including chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids.	26582039
Inflammation, Adenocarcinoma of lung (disorder)	Altered Intercellular Communication	Thus, we aimed to analyze whether chronic inflammation or immunosuppression predominates at the systemic level in lung adenocarcinoma patients, and several cytokines and Th17 and Treg cells were studied.	26582240
Inflammation	Altered Intercellular Communication	Conclusions The magnitude of acute exercise-induced inflammation following upper-body resistance exercise in women with BCRL does not vary between resistance exercise loads.	26582633
Tegumentary leishmaniasis susceptibility	Altered Intercellular Communication	Unfettered inflammation is thought to play critical role in the development of different clinical forms of tegumentary leishmaniasis.	26582954
Inflammation, Autoimmune Diseases, Fibrosis Assessment, Sample Size Calculation, Microcirculatory Bed	Altered Intercellular Communication	Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by microvascular damage, inflammation, and fibrosis.	26584613
Inflammation	Altered Intercellular Communication	It has become increasingly evident that platelets, beyond regulating hemostasis, are important in inflammation and innate immunity.	26584613
Inflammation, neuron death	Altered Intercellular Communication	SOD1(G93A) mice treated with ASC-CM for 7 days showed reduced levels of phosphorylated p38 (pp38) in the spinal cord, a mitogen-activated protein kinase that is involved in both inflammation and neuronal death.	26586020
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Relationship between Inflammation and Aspirin and Clopidogrel Antiplatelet Responses in Acute Ischemic Stroke.	26586373
Inflammation, Pleuropneumonia	Altered Intercellular Communication	A CT angiography scan of the chest and abdomen showed intralumen emboli in medial lobe segmen of right pulmonary artery, right pleuropneumonia with segmental lession in segmen 10 right lobe and inflammation process along right lateral wall of the abdomen.	26586389
Inflammation, MDFIC gene	Altered Intercellular Communication	Substantial lymphoplasmacytic inflammation (>=200 cells/mm2) was observed in 93% of HIC specimens, whereas only 8% of NHIC specimens were inflamed.	26587589
Neurodegenerative Disorders, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	The critical role of neuro-inflammation and oxidative stress in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease (AD) has become evident.	26587902
Inflammation, Hemorrhage, Edema, Dermatitis, Hypergranulosis, Solar elastosis	Altered Intercellular Communication	Major differences between LK and LE, respectively, included perivascular inflammation (11%, 90%), high Civatte bodies (44%, 7%), solar elastosis (84%, 33%), a predominate pattern of cell-poor vacuolar interface dermatitis (7%, 73%), compact follicular plugging (11%, 50%), hemorrhage (22%, 70%), mucin (0%, 77%), hypergranulosis (44%, 17%), and edema (7%, 60%).	26588332
Inflammation, Hemorrhage, Edema	Altered Intercellular Communication	Perivascular inflammation, cell-poor vacuolar interface, compact follicular plugging, mucin, hemorrhage, and edema favored LE.	26588332
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In patients with UC with endoscopic evidence of inflammation, more (86.9 %) had FC > 200 mcg/g (cut-off for disease activity in our laboratory) than had ESR >20 mm in the first hour (60.6 %) or positive CRP (65.6 %) (< 0.01); FC levels increased with increasing endoscopic Mayo score (p = 0.001) and Truelove-Witt's clinical severity score (p = 0.006), but did not correlate with disease extent (p = 0.7).	26589229
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In patients with UC with inflammation, FC > 200 mcg/g is more often positive than raised ESR or CRP; it also correlates with clinical and endoscopic activity but not with disease extent.	26589229
Pulmonary arterial hypertension, Inflammation, Polycyclic Hydrocarbons, Aromatic	Altered Intercellular Communication	A proliferative endothelial cell phenotype, inflammation, and pulmonary vascular remodeling are prominent features of pulmonary arterial hypertension (PAH).	26589479
Inflammation, Reperfusion Injury	Altered Intercellular Communication	[Effect of Shenxiong injection on inflammation injury of ischemia-reperfusion injury rats].	26591534
Inflammation	Altered Intercellular Communication	Moreover, CRP, Complement-3 (C3), C4 IL-4, IL-5, IL-1b and IL-17A levels of serum were investigated as an apoptotic marker and a negative marker for inflammation.	26592187
Inflammation, Allergic	Altered Intercellular Communication	In contrast to STAT3-HIES, DOCK8-HIES patients showed more severe inflammation with regard to allergic manifestations, elevated activation markers (HLA-DR, CD69, CD86, and CD154), and significantly increased inflammatory cytokines (IL1-beta, IL4, IL6, and IFN-gamma).	26592211
Inflammation, Primary malignant neoplasm, Pathology, Benign prostatic hypertrophy, Acute retention of urine, Structure of posterior cerebral artery	Altered Intercellular Communication	To explore the spectrum of pathologies diagnosed in prostatic biopsies of Saudi men, and test whether the frequency of diagnosing the malignant fraction has been changed over the last 15 years, and assess the association between chronic inflammation (CI) with both benign prostatic hyperplasia (BPH) and cancer (PCa), and investigate the histological findings of cases presented with acute urinary retention (AUR) clinically.	26593165
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Chronic inflammation is more related to BPH than to PCa.	26593165
Inflammation, Hypoxia	Altered Intercellular Communication	Adipose tissue hypoxia appears to play a role in promoting chronic inflammation and the development of obesity-related cardiovascular and metabolic diseases, yet the underlying mechanisms are not well understood.	26593323
Inflammation	Altered Intercellular Communication	Sirtuins are a class of proteins with important physiologic roles in metabolism and inflammation.	26595549
pathologic fistula, Complication, Inflammatory disease of mucous membrane, Ulcer	Altered Intercellular Communication	Denovo CD was diagnosed when mucosal inflammation (5 or more ulcers) involved the small bowel mucosa proximal to the ileal pouch any time after surgery and/or when a pouch fistula or other perianal complication developed more than 3 months after ileostomy closure.	26595552
Inflammation, Diarrhea	Altered Intercellular Communication	Patients who developed denovo CD had an increased incidence of nonbloody diarrhea (n = 12; 29%) compared with patients who had no evidence of pouch inflammation (n = 25; 16%) (P = 0.03).	26595552
Inflammation, Weight decreased	Altered Intercellular Communication	In contrast, the incidence of weight loss was not significantly increased in patients with denovo CD (n = 7; 17%) compared with patients who never had pouch inflammation (n = 16; 10%) (P = 0.12).	26595552
Inflammation, Atherosclerosis	Altered Intercellular Communication	Lower heart rate variability (HRV) is associated with the inflammation that is linked with the progression of atherosclerosis.	26595902
Inflammation, Abnormal sudomotor regulation	Altered Intercellular Communication	Lowered HRV, primarily due to parasympathetic dysfunction, was associated with elevated inflammation, independent of weight, insulin sensitivity, and other related factors.	26595902
Inflammation, Pancreatitis, Pancreatic carcinoma	Altered Intercellular Communication	Diffusion-weighted MR imaging of pancreatic cancer and inflammation: Prognostic significance of pancreatic inflammation in pancreatic cancer patients.	26596539
Poi serotype, Postoperative ileus, Inflammation	Altered Intercellular Communication	Postoperative ileus (POI) is a frequent complication after abdominal surgery, resulting from an inflammation of the muscularis externa (ME).	26596561
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	These findings indicate that pathogenic memory T cell responses are controlled by both CD28 and CTLA-4/PD-L1 cosignals in vivo and that selectively targeting CD28 would help to promote remission of autoimmune diseases and control chronic inflammation.	26597009
Inflammation, Pancreatitis, Pancreatic carcinoma	Altered Intercellular Communication	Subclinical Inflammation and Endothelial Dysfunction in Patients with Chronic Pancreatitis and Newly Diagnosed Pancreatic Cancer.	26597191
Inflammation, Adenocarcinoma of pancreas, Endothelial dysfunction	Altered Intercellular Communication	We studied endothelial dysfunction and subclinical inflammation in patients with newly diagnosed pancreatic adenocarcinoma and CP.	26597191
Inflammation, Diverticulum	Altered Intercellular Communication	Two observers analyzed MR images for the presence, location, number, and size of diverticula, wall thickness, and mural and extramural patterns of inflammation.	26597545
Diverticulitis	Altered Intercellular Communication	Diverticulitis occurred in 3/7 patients (43 %) showing asymmetric bowel wall thickening and focal mesenteric inflammation.	26597545
Inflammation, Multiple diverticula	Altered Intercellular Communication	Asymmetric, focal mesenteric and mural inflammation and presence of multiple diverticula are keys to diagnosis.	26597545
Bowel diverticulosis, Diverticulitis, Diverticulum, Diverticulitis of small intestine	Altered Intercellular Communication	* Small bowel diverticulosis and diverticulitis is rare and often missed in imaging * Acquired small bowel diverticula are variable in size and number * Small bowel diverticulitis demonstrates characteristic features on MR enterography/enteroclysis * A focal or segmental asymmetric small bowel inflammation should prompt the search for diverticula.	26597545
Inflammation	Altered Intercellular Communication	Importantly, we found that the skewing of circulating Tfh toward the Th1/Th17-like cells was directly correlated with B cell inflammation and low density lipoprotein level in CAD patients.	26597829
Inflammation	Altered Intercellular Communication	Together, our data demonstrated a skewing of blood Tfh composition in CAD patients, which resulted in significant changes in B cell inflammation.	26597829
Inflammation, Uveitis	Altered Intercellular Communication	All patients underwent slit lamp examination by a uveitis specialist, and the degree of scleral inflammation was recorded.	26597942
Inflammation, Secondary malignant neoplasm of liver, Primary malignant neoplasm	Altered Intercellular Communication	A positive association between hepatic metastasis (P = 0.004), primary lung cancer (P = 0.021), PC only (P < 0.001), lower Karnofsky Performance Status (P < 0.001), and higher systemic inflammation (mGPS 1/2) was found.	26598040
Minimal Disseminated Disease, Inflammation	Altered Intercellular Communication	These data demonstrate that the AA/EPA+DHA ratio moderates the effect of poor sleep on risk for developing IFN-MDD and may have broader implications for predicting and preventing MDD associated with inflammation.	26598106
Arthralgia, Rheumatoid Arthritis, Functional Disability	Altered Intercellular Communication	Rheumatoid arthritis is a chronic inflammatory condition characterized by joint pain, stiffness, and functional disability.	26598284
Inflammation, Autoinflammatory disorder	Altered Intercellular Communication	Taken together, our data envision a novel role for adaptive immunity in the pathogenesis of TNFR-associated periodic syndrome involving both CD4(+) conventional T cells and Tregs, suggesting a novel mechanism of inflammation in the context of autoinflammatory disorders.	26598380
Inflammation, Non-alcoholic Fatty Liver Disease, Metabolic Syndrome X	Altered Intercellular Communication	In addition, the incidence of metabolic syndrome and non-alcoholic fatty liver disease (NAFLD) is closely linked with the increase in inflammation and the disorders of lipid metabolism.	26598837
Inflammation, Phylum Nematoda	Altered Intercellular Communication	Nematode carcasses may remain preserved in the human eye for extended periods without ongoing inflammation.	26599254
Acute Kidney Injury, CTCAE, Inflammation, Cardiac dysfunction, Sepsis	Altered Intercellular Communication	TLR2, associated with deleterious systemic inflammation, cardiac dysfunction, and acute kidney injury, acts synergistically in sepsis.	26599367
Inflammation, diabetic	Altered Intercellular Communication	Coronary inflammation and healing influence outcomes of diabetic patients treated with Percutaneous coronary revascularization (PCI).	26599681
Inflammation	Altered Intercellular Communication	Stents covered with biodegradable polymers (bp) may offer advantages over nonerodible polymer ones, because polymer reabsorption extinguish coronary inflammation and favours healing.	26599681
Airway structure, Bronchiolitis Obliterans	Altered Intercellular Communication	We found no statistically significant association with acute cellular rejection, airway inflammation, or bronchiolitis obliterans and the presence or absence of antibodies.	26601715
Acute Lung Injury, Alveolar damage	Altered Intercellular Communication	However, biopsy specimens with DSAs had a statistically significant difference vs NABs in the setting of acute lung injury, with or without diffuse alveolar damage (p = 0.0008), in the presence of capillary neutrophilic inflammation (p = 0.0014), and in samples with endotheliitis (p = 0.0155).	26601715
Acute Lung Injury, Inflammation	Altered Intercellular Communication	Capillary inflammation, acute lung injury, and endotheliitis significantly correlated with DSAs.	26601715
Inflammation	Altered Intercellular Communication	Coronary artery bypass grafting (CABG) with conventional cardiopulmonary bypass (CPB) induces systemic inflammation.	26602006
Inflammation, Ground Glass Opacity	Altered Intercellular Communication	The inflammation promptly decreased, and follow-up chest CT revealed the disappearance of the ground-glass opacities.	26602404
Inflammation, Cholecystitis	Altered Intercellular Communication	The endoscopic retrograde cholangiopancreatography findings revealed obstruction of the cystic duct and stenosis of the hilar bile duct due to inflammation of the cystic duct or inflammation of the clamping type by cholecystitis.	26602408
Inflammation, Swyer-James Syndrome, Fibrosis Assessment, Bronchiolitis Obliterans	Altered Intercellular Communication	Swyer-James syndrome is a complication of post-infectious bronchiolitis obliterans that causes inflammation and fibrosis of the bronchial walls.	26603001
Chronic granulomatous disease, Gastrointestinal inflammation	Altered Intercellular Communication	Subclinical intestinal inflammation in chronic granulomatous disease patients.	26603166
Gastrointestinal inflammation	Altered Intercellular Communication	Fecal calprotectin concentration is a marker for intestinal inflammation.	26603166
Chronic granulomatous disease, Gastrointestinal inflammation	Altered Intercellular Communication	We sought to determine whether subclinical intestinal inflammation occurs in asymptomatic chronic granulomatous disease patients.	26603166
Retinal Detachment, Inflammation, Macular Edema, Cystoid, Eye Hemorrhage	Altered Intercellular Communication	Postoperative complications included elevated intraocular pressure (13.8%), optic capture (12.3%), persistent anterior chamber inflammation (6.2%), IOL tilt (4.6%), cystoid macular edema (3.1%), recurrent ocular hemorrhage (3.1%), and retinal detachment (1.5%).	26603392
Inflammation, Impaired cognition	Altered Intercellular Communication	Despite significantly increased inflammation observed in the older group, none of the inflammatory markers were associated with neurocognitive impairment among older HIV+ individuals (p > 0.05).	26603568
Inflammation, Asthma, Atherosclerosis	Altered Intercellular Communication	ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) is a universally confirmed susceptibility gene for asthma and has recently emerged as a crucial modulator in lipid metabolism, inflammation and endoplasmic reticulum (ER) stress-the mechanisms also closely involved in atherosclerosis (AS).	26603569
Inflammation, Colitis	Altered Intercellular Communication	IL-9 antibody injection suppresses the inflammation in colitis mice.	26603936
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Diverse T help (Th) cells play a crucial role in the processing and maintaining of chronic inflammation as seen in ulcerative colitis (UC).	26603936
Inflammation, Colitis	Altered Intercellular Communication	Anti-IL-9 antibody injection for 2 weeks reduced the severity of inflammation in DSS induced colitis mice.	26603936
Colorectal Carcinoma	Altered Intercellular Communication	Comparison of selected inflammation-based prognostic markers in relapsed or refractory metastatic colorectal cancer patients.	26604648
Colorectal Carcinoma	Altered Intercellular Communication	To investigate the impact of systemic inflammation-based prognostic markers on overall survival in relapsed/refractory metastatic colorectal cancer (mCRC) patients.	26604648
Inflammation, Dryness (characteristic)	Altered Intercellular Communication	The occurrence of repetitive dry eye is accompanied by inflammation.	26604661
Inflammation	Altered Intercellular Communication	Erdosteine reduces inflammation and time to first exacerbation postdischarge in hospitalized patients with AECOPD.	26604731
Airway structure	Altered Intercellular Communication	ER significantly reduced airway inflammation, improved the symptoms of AECOPD, and prolonged time to first exacerbation.	26604731
ARCN1 gene, Inflammation	Altered Intercellular Communication	Chronic low-grade systemic inflammation and oxidative stress play a significant role in CAD and COPD.	26605517
Inflammation, hepcidin	Altered Intercellular Communication	In our observation, IV iron infusion does not induce more nontransferrin bound iron, lipid, or protein oxidation in patients compared with volunteers, despite higher inflammation, oxidative stress, and hepcidin levels and lower antioxidant at baseline.	26605680
Inflammation, Joint tenderness	Altered Intercellular Communication	Following rotation, loadings indicated that factor 1 comprised markers of peripheral inflammation: change in ESR, swollen joints, tender joints, and global health.	26605992
Inflammation	Altered Intercellular Communication	This distinct loading led to factor 1 being labeled peripheral inflammation.	26605992
Pain Distress Question, Inflammation, Fatigue	Altered Intercellular Communication	Conversely, factor 2 comprised change in pain, fatigue, and global health and an absence of peripheral inflammation markers and was therefore labeled central inflammation.	26605992
Pain Distress Question, Inflammation, Fatigue	Altered Intercellular Communication	Following anti-TNF therapies, reductions in fatigue and pain appear to reflect improvements in central, rather than peripheral, inflammation.	26605992
Inflammation	Altered Intercellular Communication	This may result in prolonged survival of P gingivalis, possibly driving autoantibody formation and a self-perpetuating loop of chronic inflammation.	26606260
Lymphoma	Altered Intercellular Communication	Cases were patients who developed lymphoma after diagnosis of primary SS and were mainly recruited through the Club Rhumatismes et Inflammation network.	26606524
Mucous Membrane, Inflammation	Altered Intercellular Communication	Short-chain fatty acids, mainly butyrate, are the major fuel source for the epithelium and their absence in the diverted tract may produce mucosal atrophy and inflammation.	26607831
Inflammation, Atrophic	Altered Intercellular Communication	To investigate whether the administration of sodium butyrate enemas (Naburen((c)), Promefarm, Italy) could prevent mucosal inflammation and atrophy and affect gene expression profiles after ileo/colostomy.	26607831
Osteoporosis	Altered Intercellular Communication	Age-related osteoporosis is thought to be determined by a number of intrinsic factors including genetics, hormonal changes, changes in levels of oxidative stress, or an inflammatory status associated with the aging process.	26608808
Refractory anemias, Inflammation	Altered Intercellular Communication	Thus, MBDA score may be a useful objective measure for identifying RA patients with active inflammation when CRP is low (1.0 mg/dl), including RA patients with concomitant FM.	26608972
ARCN1 gene, Inflammation	Altered Intercellular Communication	Increased serum TRAIL and DR5 levels correlated with lung function and inflammation in stable COPD patients.	26609227
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is associated with abnormal systemic inflammation, and apoptosis is one of the pathogenic mechanisms of COPD.	26609227
ARCN1 gene, Inflammation	Altered Intercellular Communication	Then, serum levels of TRAIL and DR5 in 57 COPD patients with 35 healthy controls were compared and correlated with lung function and systemic inflammation.	26609227
ARCN1 gene, Inflammation	Altered Intercellular Communication	Our results suggested that circulating TRAIL and DR5 increased in COPD patients and were associated with lung function and systemic inflammation in COPD.	26609227
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Increased inflammation in rheumatoid arthritis patients living where farm soils contain high levels of copper.	26610397
hearing impairment, Inflammation	Altered Intercellular Communication	Low-grade inflammation and microvessel pathology may be responsible for initiating or exacerbating some of the hearing loss associated with aging.	26611434
Inflammation	Altered Intercellular Communication	A shared etiological pathway may include a role of inflammation, alongside vascular determinants.	26611434
Inflammation, Acute appendicitis NOS (disorder)	Altered Intercellular Communication	CT of the abdomen and pelvis showed evidence of inflammation in the peritoneal soft tissues adjacent to an enlarged and thick-walled appendix, an appendicolith, no abscess formation and a slightly thickened caecum consistent with acute appendicitis.	26611488
Inflammation	Altered Intercellular Communication	The role of inflammation in the development of age-related diseases is widely recognized.	26611787
Inflammation	Altered Intercellular Communication	Our findings suggest that, in contrast to inflammation, immunosenescence appears to be highly dependent on HIV-infection and is only to a small extent associated with age-related parameters in well-treated HIV-infection.	26611787
Inflammation, Necrosis	Altered Intercellular Communication	The presence of zirconia particles results in frustrated digestion attempts by macrophages, liberation of inflammatory mediators, and necrosis leading to aseptic inflammation and osteolyses.	26612414
Cessation of life, Inflammation	Altered Intercellular Communication	Cellular inflammation, mainly consisting of functional cytotoxic T lymphocytes, was observed together with adipocyte cell death in human atria.	26612579
Inflammation	Altered Intercellular Communication	Murine IL-29 counterpart induces skin T-cell infiltration and inflammation in mice.	26612594
Inflammation, Fibrosis Assessment, Hallopeau-Siemens Disease	Altered Intercellular Communication	The purpose of this investigation was to elucidate the mechanisms of impaired wound healing and pseudosyndactyly occurring in RDEB patients by studying the role of known inflammation and fibrosis markers in RDEB pseudosyndactyly tissue.	26612796
Inflammation, Fibrosis Assessment, Epidermolysis Bullosa Dystrophica	Altered Intercellular Communication	Our results confirm inflammation and fibrosis in recessive dystrophic epidermolysis bullosa, especially in scars, suggesting major roles for these processes in pseudosyndactyly.	26612796
Necrotizing granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	Open liver biopsy yielded chronic granulomatous inflammation compatible with pathological findings of tuberculosis infection.	26613227
Deficit, Neurodegenerative Disorders, Disease, Hypoperfusion	Altered Intercellular Communication	Both disorders appear to involve inflammation-related hyper-histaminemia, oxidative stress, autoimmune response, capsulothalamic hypoperfusion and BBB opening, and a deficit in melatonin metabolic availability; suggesting a risk of chronic neurodegenerative disease.	26613326
Inflammation, Joints	Altered Intercellular Communication	This study describes for the first time, in a large cohort of healthy subjects, the prevalence and location of US signs of joint inflammation and of structural damage in small joints of hands and feet.	26613767
Inflammation	Altered Intercellular Communication	This suggests that subclinical inflammation is present and that natural anticoagulant/thrombomodulin activity is important after transplant.	26614396
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Coffee may reduce mortality risk by favorably affecting inflammation, lung function, insulin sensitivity, and depression.	26614599
Inflammatory abnormality of the eye, Dry Eye Syndromes, Congenital stationary cone dysfunction	Altered Intercellular Communication	Ocular surface inflammation is one of the primary mechanisms associated with dysfunctional tear syndrome (DTS), also known as dry eye disease.	26615568
Inflammation, Mental disorders, Traumatic injury	Altered Intercellular Communication	Particularly strong evidence indicates that childhood adversity and adulthood trauma exposure increase risk for physical and psychiatric disorders, and there is emerging evidence that inflammation may play a key role in these relationships.	26616398
Inflammation	Altered Intercellular Communication	Our study demonstrates the prevalence of trauma-related inflammation in the general population and suggests that childhood adversity and adulthood trauma are independently associated with elevated inflammation.	26616398
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Neutrophilic inflammation plays a causal role in Chronic Obstructive Pulmonary Disease (COPD).	26616678
ARCN1 gene, Inflammation	Altered Intercellular Communication	It was thus reasoned that doxycycline may attenuate neutrophil-mediated inflammation in COPD.	26616678
Inflammation	Altered Intercellular Communication	In order to exclude inflammation by bacterial colonisation patients must have 2 negative sputum cultures in the previous year.	26616678
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	It has been observed from the experiment which was designed on the basis of the correlation between inflammation reaction and essential hypertension that the content of urine UMOD protein of essential hypertension patients who is in stage I was (28.71 +- 10.53) mg/24 h and when compared with the control group's content (30.15 +- 14.10 mg/24 h), the difference was not obviously; The content of urine UMOD protein of essential hypertension patients who's in stage II and III was (18.24 +- 6.12) mg/24 h and (9.43 +- 3.16) mg/24 h, respectively, which were obviously lower than that of the control group (P<0.01).	26617860
Malignant neoplasm of urinary bladder, Inflammation, Carcinoma	Altered Intercellular Communication	Their bladder mucosal tissues were taken from the random biopsy of bladder cancer suspected patients without any finding such as inflammation or carcinoma in situ.	26617941
Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation has gained a pivotal role in the pathophysiology of Acute Coronary Syndrome (ACS).	26618233
Inflammation, Pancreatic carcinoma	Altered Intercellular Communication	Vagal nerve activity predicts overall survival in metastatic pancreatic cancer, mediated by inflammation.	26618335
Inflammation	Altered Intercellular Communication	Here we describe how different sialylation statuses of IgG autoantibodies contribute to the complex inflammatory network that regulates chronic inflammation.	26618514
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Studies suggest that tumour-infiltrating lymphocytes (TILs) and inflammation markers have independent roles in non-small cell lung cancer (NSCLC), but the relationship between the two pronostic factors remains unclear.	26619201
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Increased CD3+ and low CD5+ was observed in patients with poor prognosis; the two molecules were correlated with NLR, suggesting that inflammation might be used as improve therapeutic efficacy to immunotherapy for advanced NSCLC.	26619201
Inflammation, Immune System Diseases	Altered Intercellular Communication	Importantly, exercise did not exacerbate systemic inflammation or immune dysfunction; intradialytic exercise was well tolerated.	26619202
Inflammation, 4-hydroxy-2-oxovalerate aldolase activity, Joint tenderness	Altered Intercellular Communication	The higher frequency of joint tenderness in erosive HOA was at least partly explained more structural damage and inflammation.	26620088
hyperthermia treatment, Inflammation, Intracranial Hemorrhage, Intracranial Hypertension, Hypoxia, Cerebral Edema, Hypotension, CTCAE, Hypothermia due to exposure, Shock, Brain Injuries	Altered Intercellular Communication	Secondary brain injury occurs several hours or days after primary brain injury and is the result of factors including shock, systemic hypotension, hypoxia, hypothermia or hyperthermia, intracranial hypertension, cerebral oedema, intracranial bleeding or inflammation.	26620118
Inflammation	Altered Intercellular Communication	The study data indicate that inflammation is the most important cause of secondary insults.	26620118
Inflammation, Telangiectasis, Raynaud Phenomenon, CREST Syndrome, Sclerodactyly, Calcinosis, Laryngitis	Altered Intercellular Communication	The second patient was a 67-year-old woman with severe vocal fold inflammation related to laryngitis and calcinosis, Raynaud's phenomenon, esophagean dysmotility, sclerodactyly, and telangiectasia (CREST) syndrome.	26620260
Inflammation	Altered Intercellular Communication	YKL-40 is an extracellular matrix glycoprotein with a significant role in tissue inflammation and remodeling.	26620310
Airway structure	Altered Intercellular Communication	Airway inflammation was assessed with the fraction of exhaled nitric oxide (FeNO) and participants exhaled at various exhalation flows to determine alveolar and bronchial NO.	26620577
Airway structure, Obesity	Altered Intercellular Communication	Obesity does not influence airway inflammation as measured by FeNO.	26620577
Inflammation, Atherosclerosis	Altered Intercellular Communication	Positive association of plasma sCD36 with insulin resistance has been reported, and it has been proposed that sCD36 might represent a marker of macrophage activation and inflammation leading to atherosclerosis.	26620683
Inflammation	Altered Intercellular Communication	Our findings confirmed a central role for inflammation and proteases in plaque instability, and highlighted haemoglobin metabolism and bone resorption as important pathways.	26620734
Inflammation, Calcinosis	Altered Intercellular Communication	Subgroup analysis suggested prolonged inflammation following the symptoms of plaque instability and calcification as a possible stabilizing mechanism by statins.	26620734
Inflammation	Altered Intercellular Communication	HO-1 (3.91 vs. 5.67; p < 0.05) and HO-2 (1.06 vs. 1.37; p < 0.05) were significantly reduced in patients with high intra-prostatic inflammation (Irani score >=4).	26621207
Inflammation	Altered Intercellular Communication	MetS-induced inflammation may play a key role in BPH.	26621207
Osteomyelitis, Inflammation, Necrosis	Altered Intercellular Communication	Articular MRI showed inflammation and necrosis of both knees and ankles, and left hip and right elbow (compatible with osteomyelitis).	26621903
Inflammation, Neoplasms	Altered Intercellular Communication	Imaging findings of residual cervical tumor after chemoradiotherapy can closely resemble those of post-irradiation inflammation.	26622060
Inflammation	Altered Intercellular Communication	Eleven out of 41 (27%) patients showed inflammation with false positive post-chemoradiotherapy MRI and 1/41 (2%) had a false negative post-chemoradiotherapy MRI.	26622060
Inflammation, Neoplasms	Altered Intercellular Communication	The differentiation of residual tumor from post-irradiation inflammation with early post- chemoradiotherapy MRI (within 28-60 days) is difficult with a high risk of false positive results.	26622060
Inflammation, Kidney Diseases	Altered Intercellular Communication	The progression of kidney disease is significantly associated with inflammation, which could in the future be useful in prognostic and therapeutic purposes.	26622082
Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Connection of CKD with inflammation and proven connection of inflammation with cardiovascular risk indicates the potential value of some biomarkers, which could in the future identify as predictors of outcome and could have the benefit in the early diagnosis and treatment of cardiovascular disease in CKD.	26622082
Granulomatous inflammation, Sarcoidosis, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	The biopsy specimen exhibited non-caseating, granulomatous inflammation and many multinucleated giant cells, strongly suggesting sarcoidosis.	26624970
Coinfection	Altered Intercellular Communication	HIV co-infection (aOR=3.44, p<0.001) and hormonal contraception (aOR=1.97, p=0.007) were associated with increased HPV prevalence.	26625088
Inflammation, Autoimmune hemolytic anemia	Altered Intercellular Communication	Laboratory tests show signs of autoimmune hemolytic anemia, elevated liver function tests, and moderate laboratory signs of inflammation.	26625239
Inflammation	Altered Intercellular Communication	Pathological changes due to inflammation were observed in the biopsy and esophagography.	26625471
Inflammation, Diabetic Retinopathy	Altered Intercellular Communication	Altered circulating mitochondrial DNA and increased inflammation in patients with diabetic retinopathy.	26625720
Diabetic Retinopathy, Inflammation	Altered Intercellular Communication	Our data show that circulating MtDNA levels are independently associated with diabetic retinopathy, showing an increase in DR-m and decrease in DR-s with a parallel increase in MtDNA damage and inflammation.	26625720
Inflammation, Diabetic Retinopathy, Diabetes Mellitus	Altered Intercellular Communication	Hyperglycemia-induced changes in MtDNA in early diabetes may contribute to inflammation and progression of diabetic retinopathy.	26625720
PROS1 gene, Inflammation	Altered Intercellular Communication	In addition, flare of joint inflammation in PsA patients has also been reported.	26626908
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	In CKD, interleukin-6 and hypersensitive C-reactive protein are known to be used for the evaluation of inflammation and serum levels increase with decreased creatinine clearance.	26627016
Inflammation, hepcidin	Altered Intercellular Communication	Inflammation related hepcidin and NGAL weakly correlated with creatinine clearance.	26627016
Inflammation, hepcidin, Chronic Kidney Diseases	Altered Intercellular Communication	Our results demonstrated that serum NGAL and hepcidin levels might be valuable for the evaluation of inflammation in CKD, and these new inflammation parameters are not related through iron metabolism.	26627016
hepcidin	Altered Intercellular Communication	Neutrophil gelatinase-associated lipocalin (NGAL) and hepcidin are also considered to be effective in the assessment of inflammatory conditions.	26627016
Genus Axis, HIV Infections	Altered Intercellular Communication	Inflammation Perturbs the IL-7 Axis, Promoting Senescence and Exhaustion that Broadly Characterize Immune Failure in Treated HIV Infection.	26627102
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	In histopathological evaluation of biopsy specimens according to Sydney criteria, chronic inflammation, activity, atrophy, intestinal metaplasia and helicobacter pylori parameters were used.	26627512
Inflammation	Altered Intercellular Communication	The degree of activation and severity of inflammation increased significantly with increasing helicobacter pylori positivity(r=0.459'p<0.0001; r=0.475'p<0.0001).	26627512
Inflammation	Altered Intercellular Communication	There was also a statistically significant correlation between severity of inflammation and activation and the number of eosinophils (r=0.313;p=0.002;r=0.245;p=0.016).	26627512
Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	The development of acute respiratory distress syndrome (ARDS) is associated with dys-regulated inflammation.	26627982
Interstitial inflammation	Altered Intercellular Communication	Specifically, hESC-MSC treatment prevented disease-associated interstitial inflammation, protein cast deposition, and infiltration of CD3(+) lymphocytes in the kidneys.	26628350
Inflammation, Liver carcinoma, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Liver Cirrhosis	Altered Intercellular Communication	Nonalcoholic fatty liver disease (NAFLD) represents a spectrum of disorders from simple steatosis to inflammation leading to fibrosis, cirrhosis, and even hepatocellular carcinoma.	26629307
Inflammation, Damage	Altered Intercellular Communication	No correlation was observed between the intensity and type of dermal inflammation and the degree of epidermal damage or the culprit drug.	26630685
Inflammation, Bladder Adenocarcinoma	Altered Intercellular Communication	Cystoscopy and biopsy revealed an adenocarcinoma of the anterior bladder and stoma with extensive associated mucin production and a background of acute and chronic inflammation.	26630940
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	High-dose omega-3 fatty acids did not reduce arterial PWV or markers of inflammation among patients within a Latino-predominant population with hypertension.	26631058
Inflammation, proIslet peptide, human	Altered Intercellular Communication	Apigenin Attenuates Inflammation in Experimentally Induced Acute Pancreatitis-Associated Lung Injury.	26631908
Conjunctivitis	Altered Intercellular Communication	Treatment with doxycyline, dapsone, and mycophenolate mofetil was unsuccessful and treatment with rituximab has led to partial remission of the conjunctival inflammation.	26632795
Inflammation, Neoplasms	Altered Intercellular Communication	Infiltrating neutrophils, lymphocytes, macrophages, and cytokines constitute a state of chronic inflammation within the tumor microenvironment.	26632898
Inflammation	Altered Intercellular Communication	Tartrate-resistant acid phosphatase 5a (TRACP5a) protein, a novel product of activated macrophage, is postulated to be a biomarker for systemic inflammatory burden in states of chronic inflammation.	26632898
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	High levels of serum long chain saturated fatty acids (LCSFAs) have been associated with inflammation in type 2 diabetes.	26633920
Gastrointestinal inflammation	Altered Intercellular Communication	Faecal (f-) calprotectin is a biomarker of intestinal inflammation.	26634305
ARCN1 gene, Chronic Obstructive Airway Disease, Carcinoma of lung, Airway structure	Altered Intercellular Communication	Asthma and COPD (chronic obstructive pulmonary disease) lead to persistent airway inflammation and are associated with lung cancer.	26634452
Inflammation, Fibrosis Assessment, Injury of liver	Altered Intercellular Communication	Primary outcome measures include change in hepatic injury (fibrosis and inflammation) and liver fat.	26635079
Inflammation, Atherosclerosis, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology, vascular inflammations	Altered Intercellular Communication	Vascular inflammation plays a key role in the development of atherosclerosis and acute coronary syndrome (ACS), and pentraxin 3 (PTX3) is one of several novel, promising markers of inflammation.	26635361
atherosclerotic	Altered Intercellular Communication	Serum cyclin-dependent kinase 9 is a potential biomarker of atherosclerotic inflammation.	26636538
Inflammation, Atherosclerosis	Altered Intercellular Communication	Altogether, These findings indicate that CDK9 represent an important role for inflammation in the pathogenesis of atherosclerosis.	26636538
atherosclerotic	Altered Intercellular Communication	It may be a potential biomarker of atherosclerotic inflammation and offer insights into the pathophysiology and targeted therapy for atherosclerotic CAD.	26636538
Inflammation	Altered Intercellular Communication	Inflammation is a condition stemming from complex host defense and tissue repair mechanisms, often simply characterized by plasma levels of a single acute reactant.	26636573
HD Term Type, Inflammation	Altered Intercellular Communication	The role of inflammation and the significance of non-neuronal involvement in HD pathogenesis suggest anti-inflammatory therapeutics may offer important opportunities in treating HD.	26636579
Inflammation, Disease, Candida (fungus)	Altered Intercellular Communication	The proof of multiresistant pathogens or Candida, as well as the level of inflammation markers, have an impact on the prognosis of the underlying tumor disease.	26637394
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Fungus-driven inflammation is proposed to play an important role in the pathogenesis of chronic rhinosinusitis (CRS).	26637583
Inflammation, AHSP gene, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation plays a prominent role in the etiology of the early recurrence of atrial fibrillation (ERAF).	26638872
Ischemia, Metabolic Diseases, Inflammation, Demyelination, Neoplasms, Communicable Diseases, Phenylketonurias	Altered Intercellular Communication	Cerebral white matter lesions (CWMLs), identified in magnetic resonance imaging (MRI), are related to various clinical conditions including ischemia, inflammation, demyelination, infection, a tumor, and metabolic disorders such as phenylketonuria.	26639091
Cholesteatoma, bone destruction, Inflammation	Altered Intercellular Communication	TLR4 drives the pathogenesis of acquired cholesteatoma by promoting local inflammation and bone destruction.	26639190
Inflammation, Acute-On-Chronic Liver Failure, CRNKL1 wt Allele	Altered Intercellular Communication	Activation of liver macrophages plays a key role in liver and systemic inflammation and may be involved in development and prognosis of acute-on-chronic liver failure (ACLF).	26639396
Cerebral Amyloid Angiopathy, Inflammation	Altered Intercellular Communication	We report a biomarker and genetic evaluation of four patients with cerebral amyloid angiopathy-related inflammation (CAA-ri) treated with corticosteroids.	26639966
Inflammation, Data types - Address, Memory impairment	Altered Intercellular Communication	These results suggest that OCGP may prevent memory impairment in AD by inhibiting Ab accumulation and inflammation in the brain.	26639976
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Elevated Biomarkers of Inflammation and Coagulation in Patients with HIV Are Associated with Higher Framingham and VACS Risk Index Scores.	26641655
Inflammation, Observation Method - Coagulation, Psychological suppression	Altered Intercellular Communication	Despite viral suppression and immunological stability, biomarkers of inflammation and coagulation remain elevated in a significant number of patients with HIV and are associated with higher scores on risk stratification indices.	26641655
ARCN1 gene, Inflammation	Altered Intercellular Communication	Haemophilus influenzae frequently colonizes the airways of COPD patients, where it enhances inflammation.	26642881
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) affects many central nervous structures and neurotransmitter systems.	26643357
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation and leukocyte infiltration are hallmarks of atherosclerosis.	26643521
Mouth Diseases, Gingivitis, Periodontitis, bone destruction	Altered Intercellular Communication	Chronic periodontitis is an oral disorder characterized with gingival inflammation and bone destruction.	26643602
Inflammation, Units Of Measure - Siemens, Metabolic Syndrome X	Altered Intercellular Communication	Second, MHO was defined as being free of all metabolic syndrome criteria, insulin resistance and inflammation.	26643813
Inflammation, Units Of Measure - Siemens	Altered Intercellular Communication	Associations between dietary components and MHO were weak and inconsistent, while physical activity and inflammation were not associated with MHO in male and female adolescents for both definitions (p > 0.05).	26643813
Inflammation	Altered Intercellular Communication	Zinc dyshomeostasis may lead to an augmented production of proinflammatory cytokines promoting chronic inflammation and increasing the susceptibility to age-related diseases.	26643924
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	C-reactive protein (CRP), a biomarker of inflammation, may correlate with prognosis in several malignancies.	26643974
FAM126A gene	Altered Intercellular Communication	Early postoperative serum CRP may serve as a useful inflammation-based biomarker of outcome in liver transplant patients with HCC.	26643974
Communicable Diseases, Carcinogenesis, Inflammation, Infective vaginitis	Altered Intercellular Communication	Vaginal infections may affect susceptibility to and clearance of human papillomavirus (HPV) infection and chronic inflammation has been linked to carcinogenesis.	26644228
Kidney Failure, Chronic, Inflammation, Malnutrition, Diabetes Mellitus, Systemic disease, Hypertension, CTCAE	Altered Intercellular Communication	In this cohort of incident end-stage renal disease patients with diabetes, poor glycemic control was independently associated with younger age, Native American race, Hispanic ethnicity, higher body mass index, and clinical risk factors including atherogenic lipoprotein profile, hypertension, inflammation, and markers indicative of malnutrition and a more serious systemic disease.	26645204
Sepsis, Inflammation	Altered Intercellular Communication	A Molecular Host Response Assay to Discriminate Between Sepsis and Infection-Negative Systemic Inflammation in Critically Ill Patients: Discovery and Validation in Independent Cohorts.	26645559
Sepsis, Inflammation	Altered Intercellular Communication	Systemic inflammation is a whole body reaction having an infection-positive (i.e., sepsis) or infection-negative origin.	26645559
Inflammation, Eating	Altered Intercellular Communication	EAT in CAD is characterized by changes in the regulation of metabolism and inflammation with miR-103-3p/CCL13 pair as novel putative actors in EAT function and CAD.	26645979
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Detailed cytological examination revealed necrotizing granulomatous inflammation as most common pattern (43%).	26646425
Inflammation, anatomical bulb, conjunctiva	Altered Intercellular Communication	Conjunctival sensation was tested by Cochet-Bonnet aesthesiometer in four quadrants of the bulbar conjunctiva plus the area(s) of active or previously active inflammation; sensation was compared with the contralateral eye.	26647348
Inflammation, Scleritis, conjunctiva	Altered Intercellular Communication	Conjunctival sensation is decreased in areas of previously active inflammation from scleritis.	26647348
Inflammation, Herpetic Gastritis, conjunctiva	Altered Intercellular Communication	Eyes with herpetic scleritis had reduced conjunctival sensation, even in areas without previous active inflammation.	26647348
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Asthma is a chronic inflammatory disorder of the airways where bacteria may act as protagonists of chronic inflammation.	26647445
Airway structure	Altered Intercellular Communication	Little is known about the relation of airway inflammation to the presence of specific bacterial taxa.	26647445
Crohn Disease, Inflammation, Spondylitis	Altered Intercellular Communication	Distinct immune signatures in the colon of Crohn's disease and ankylosing spondylitis patients in the absence of inflammation.	26647966
Inflammatory Bowel Diseases, Crohn Disease, Inflammation	Altered Intercellular Communication	Crohn's disease (CD) is an inflammatory bowel disease characterized by patchy inflammation of the gastrointestinal tract.	26647966
Inflammation, Spondylitis	Altered Intercellular Communication	Ankylosing spondylitis (AS) is primarily characterized by inflammation of the lower vertebral column, and many patients with AS present with inflammatory gut symptoms.	26647966
Bone Diseases, Inflammation, Acidosis	Altered Intercellular Communication	The evaluation of acid-basic status should be routinely implemented in dialysis patients by considering the negative effects of acidosis on the nutritional status, inflammation and bone disease.	26648495
Inflammation, thromboembolic, Necrotizing, Cerebrovascular accident	Altered Intercellular Communication	The release of necrotizing factor and interleukins may cause inflammation of the endothelial lining, creating a prothrombotic surface that triggers thromboembolic events, including stroke.	26648966
Inflammation, Sarcoidosis, Pulmonary	Altered Intercellular Communication	Pulmonary sarcoidosis is classically defined by T-helper (Th) cell type 1 inflammation (e.g., IFN-g production by CD4(+) effector T cells).	26649486
vascular inflammations	Altered Intercellular Communication	In all three patients receiving interleukin-6 blockade, laboratory markers and clinical scores normalized despite persistent vascular inflammation in one patient which was disclosed by MRI.	26649990
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation in the brain is a prominent feature in Alzheimer's disease (AD).	26650044
Inflammation, Failure (biologic function)	Altered Intercellular Communication	Recent studies suggest that chronic inflammation can be a consequence of failure to resolve the inflammation.	26650044
levamisole, Inflammation, Data types - Address	Altered Intercellular Communication	Resolution of inflammation is mediated by a family of lipid mediators (LMs), and the levels of these specialized pro-resolving mediators (SPMs) are reduced in the hippocampus of those with AD.	26650044
Inflammation, Calcification of coronary artery, Cardiovascular Diseases, Microalbuminuria, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Markers of inflammation and endothelial dysfunction are associated with incident cardiovascular disease, all-cause mortality, and progression of coronary calcification in type 2 diabetic patients with microalbuminuria.	26651261
Inflammation, SLC25A20 gene, Cardiovascular Diseases, Microalbuminuria, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Coronary Artery Disease, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	We evaluated markers of inflammation and endothelial dysfunction and their associations with incident cardiovascular disease (CVD), all-cause mortality and progression of coronary artery calcium (CAC) in patients with type 2 diabetes (T2D) and microalbuminuria but without known coronary artery disease (CAD).	26651261
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Higher composite z-scores including all markers of inflammation and endothelial dysfunction were associated with CVD and all-cause mortality (p<=0.008).	26651261
Inflammation, SLC25A20 gene, Microalbuminuria, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	In patients with T2D and microalbuminuria without known CAD and receiving multifactorial treatment, biomarkers of inflammation and endothelial dysfunction were independently associated with CVD, all-cause mortality and CAC progression.	26651261
Inflammation, Gastrointestinal symptom, Chronic Kidney Diseases, Hypoalbuminemia	Altered Intercellular Communication	Gastrointestinal symptoms, inflammation and hypoalbuminemia in chronic kidney disease patients: a cross-sectional study.	26651991
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Our goal in this paper is to study how GI symptoms relate to serum albumin levels in CKD, especially in the context of and compared with inflammation.	26651991
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	But our data do not support GI symptoms/decreased protein intake or inflammation as being the main determinants of serum albumin level in CKD patients.	26651991
HMGCL gene, Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	A small increased risk of HL following appendicitis (rather than appendectomy per se) could reflect a true association, or shared susceptibility to infection/inflammation among individuals prone to develop HL.	26652908
Arthritis	Altered Intercellular Communication	Two types of self-reported symptoms, chronic joint inflammation and worn out joints, were used for the analyses.	26653129
Blindness, Communicable Diseases, Inflammation	Altered Intercellular Communication	The mass delivery of antibiotics is highly beneficial for the clearance of infection, inflammation and prevention of subsequent scarring, but needs to be supplemented with sustained reductions in transmission and surgery to consider realistically the elimination of blindness by the year 2020.	26653262
Inflammation, Rathke Cleft Cysts, Rupture, Aneurysm	Altered Intercellular Communication	The severe inflammation around the vasculature after rupture of the Rathke cleft cyst might have been involved in aneurysm formation.	26654927
Eye pain, Blurred vision, anatomical bulb, Intraocular inflammation	Altered Intercellular Communication	None of the patients complained of blurred vision, ocular pain, or bulbar injection at any of the follow-up visits, nor was intraocular inflammation noted.	26655620
Airway structure	Altered Intercellular Communication	Blocking b-catenin expression with a specific siRNA attenuated airway inflammation and airway remodeling.	26655831
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	Growing evidence showed that inflammation response plays an important role in cancer development and progression, and absolute lymphocyte count (ALC), absolute monocyte count (AMC), and lymphocyte to monocyte ratio (LMR) have been used as parameters of systemic inflammation in several tumors.	26656374
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	It has been reported nutritional status and systemic inflammation were associated with the outcome of patients with malignancies.	26656866
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Based on the knowledge that chronic obstructive pulmonary disease (COPD) starts in the small airway epithelium, we hypothesized that chronic inflammation modulates peripheral exhaled particle SP-A and albumin levels.	26656890
Inflammation, Observation Method - Coagulation, Injury of kidney	Altered Intercellular Communication	Acute kidney injury in high-risk cardiac surgery patients: roles of inflammation and coagulation.	26657082
Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	Cardiopulmonary bypass elicits coagulation and inflammation activation and oxidative stress, all involved in AKI but never simultaneously assessed.	26657082
Communicable Diseases, FBN2 wt Allele, Inflammation	Altered Intercellular Communication	Chronic inflammation and oxidative stress induced by liver fluke, Opisthorchis viverrini, infection has been recognized as the major cause of CCA in this area.	26657242
Inflammation	Altered Intercellular Communication	Removal should be considered, however, if there is a risk of it becoming infected due to implantation-induced inflammation.	26657524
Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Variants of the Coagulation and Inflammation Genes Are Replicably Associated with Myocardial Infarction and Epistatically Interact in Russians.	26658659
Inflammation	Altered Intercellular Communication	This applies as well to the genes involved in inflammation and coagulation processes, which play a crucial role in the disease etiopathogenesis.	26658659
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Simvastatin, an HMG-coA reductase inhibitor, is known to attenuate inflammation and prevent certain cancers.	26658759
Inflammation	Altered Intercellular Communication	Application of the proposed Consensus Conference grading revealed inflammatory activity in all patients with mild (33 %), moderate (44 %), or severe inflammation (23 %).	26659079
Communicable Diseases, Inflammation	Altered Intercellular Communication	Adequate suppression of cardiac glucose metabolism increases the interpretability and diagnostic reliability of (18)F-FDG PET studies performed to detect cardiac inflammation and infection.	26659348
Communicable Diseases, Inflammation	Altered Intercellular Communication	Group 1 included oncologic indications, and groups 2 and 3 infection or inflammation detection.	26659348
Communicable Diseases, Inflammation	Altered Intercellular Communication	Cardiac segments for which inflammation or infection foci had been confirmed on other imaging modalities were excluded from the analysis.	26659348
Inflammation, Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Thus, IS may play an important role in the development of cardiovascular disorders in kidney diseases during inflammation by increasing endothelial expression of E-selectin.	26659566
Acute Kidney Injury, CTCAE, Kidney Failure, Acute, Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Uremic toxins are considered a risk factor for cardiovascular disorders in kidney diseases, but it is not known whether, under inflammatory conditions, they affect adhesion molecule expression on endothelial cells, which may play a critical role in acute kidney injury (AKI).	26659566
ARCN1 gene, Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Long-term benefits of ICS on lung function decline in patients with moderate-to-severe COPD are most pronounced in patients with fewer packyears, and less severe emphysema and inflammation.	26659582
Inflammation	Altered Intercellular Communication	Systemic and intestinal levels of factor XIII-A: the impact of inflammation on expression in macrophage subtypes.	26660730
Gastrointestinal inflammation	Altered Intercellular Communication	The objective was to evaluate the consequences of intestinal inflammation on resident mucosal macrophages, focusing on the level and distribution of FXIII-A.	26660730
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Intestinal inflammation in UC induces loss of M2 macrophages with subsequent loss of FXIII-A synthesis.	26660730
Sepsis	Altered Intercellular Communication	Loss of plasma FXIII-A has been reported after surgery, sepsis, and inflammatory conditions.	26660730
Inflammation, Calcified (qualifier), Cardiovascular Diseases	Altered Intercellular Communication	Lower levels of ES and OPN in physically active patients might be a sign of increased angiogenesis and decreased inflammation and calcifying activity and therefore contribute to the understanding of the damaging effect of physical inactivity in cardiovascular disease.	26661073
Inflammation, Sample Size Calculation, Systemic Scleroderma	Altered Intercellular Communication	Cathepsin L (CTSL) is a lysosomal proteolytic enzyme involved in inflammation and vascular and extracellular matrix remodelling, which are the three cardinal pathological events associated with systemic sclerosis (SSc).	26661692
Airway structure, Bronchial Hyperreactivity	Altered Intercellular Communication	(2) To assess the relationships between sputum clusterin levels and airway inflammation, pulmonary function, and bronchial hyperresponsiveness.	26661728
Airway structure, Asthma	Altered Intercellular Communication	Clusterin may be a marker that reflects airway inflammation and severity of symptoms, and it can be used in the assessment and management of childhood asthma.	26661728
Inflammation, GDC AJCC Clinical Stage Terminology, Atherosclerosis	Altered Intercellular Communication	These findings indicate that the decrease of the frequency of Treg cells in the peripheral blood of patients with ACS might destroy the balance of tolerance of the peripheral immune system and might activate inflammation, thus participating in the occurrence and development of the pathological processes of atherosclerosis.	26662384
Inflammation, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	After excluding 121 participants with three most common causes of anaemia (chronic kidney disease, inflammation, iron deficiency), anaemia was found in 4*7% of euthyroid participants.	26662849
Esophageal	Altered Intercellular Communication	No patient in histological remission showed symptom relapse, but half of patients with relapsing oesophageal inflammation were in clinical remission.	26662868
Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation in response to oxidized lipoproteins is thought to play a key role in acute coronary syndromes (ACS), but the pattern of immune activation has not been fully characterized.	26663396
Inflammation, Portal Vein Thrombosis	Altered Intercellular Communication	This case suggests that inflammation around the portal vein as a result of C. sinensis infection has the potential to evoke portal vein thrombosis.	26663478
Inflammation	Altered Intercellular Communication	Alteration of Urothelial Inflammation, Apoptosis, and Junction Protein in Patients with Various Bladder Conditions and Storage Bladder Symptoms Suggest Common Pathway Involved in Underlying Pathophysiology.	26663690
Inflammation, Urinary Tract Physiology, physiopathological	Altered Intercellular Communication	This study investigated urothelial dysfunction and chronic inflammation in the urothelium in different types of lower urinary tract dysfunction (LUTD), which causes bladder storage symptoms.	26663690
Inflammation	Altered Intercellular Communication	Increased urothelial inflammation and urothelial cell apoptosis seem to share common pathophysiologies of various LUTDs that cause similar bladder symptoms.	26663690
Prostate	Altered Intercellular Communication	Dramatic Enlargement of the Prostate due to Xanthogranulomatous Inflammation.	26663733
Adenocarcinoma, Inflammation, Prostate	Altered Intercellular Communication	Xanthogranulomatous inflammation of the prostate is a rare condition that can cause lower urinary tract symptoms and may be mistaken for adenocarcinoma.	26663733
Inflammation	Altered Intercellular Communication	We present a case of a 78-year-old man found to have a 318 g prostate secondary to xanthogranulomatous inflammation.	26663733
Complication Aspects, Keratitis, Uveitis	Altered Intercellular Communication	A diverse spectrum of ocular complications was observed with corneal inflammation and opacification in 77% followed by anterior uveitis in 65%.	26663773
Myocardial fibrosis, Inflammation	Altered Intercellular Communication	Tenascin-C (Tn-C) and matrix metalloproteinase-9 (MMP-9) are extracellular matrix proteins associated with myocardial fibrosis and wall remodeling because of inflammation.	26663885
ARCN1 gene, Inflammation	Altered Intercellular Communication	Severe COPD patients with LVDD showed a different inflammatory pattern, suggesting a link between low-grade inflammation and the presence of LVDD.	26663885
Exacerbation of asthma, Asthma, Inflammation, Respiratory Tract Infections	Altered Intercellular Communication	Respiratory infections are a major cause of asthma exacerbations where neutrophilic inflammation dominates and is associated with steroid refractory asthma.	26663987
Pachymeningitis, Inflammatory Myofibroblastic Tumor, Neurosarcoidosis	Altered Intercellular Communication	We report a case of a 55-year-old female who had probable isolated neurosarcoidosis based on magnetic resonance imaging findings of relapsing pachymeningitis with an inflammatory process in the apex of the right orbit and pseudotumor inflammation of the superior and lateral recti of the right eye.	26666108
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	Toll-like receptor 3 (TLR3) is expressed in upper airways, however, little is known regarding whether Toll-like receptor 3 (TLR3) signals exert a regulatory effect on the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP), especially on eosinophilic inflammation.	26666485
Interstitial inflammation	Altered Intercellular Communication	An autopsy revealed diffuse interstitial inflammation of both lungs consistent with drug-induced inflammation.	26666606
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Neutrophil to lymphocyte ratio (NLR) has emerged as a marker of inflammation in neoplastic and cardiovascular disorders.	26666737
Inflammation, Anorexia	Altered Intercellular Communication	Chronic inflammation of the stomach that results in the loss of appetite and, dysregulation of neuroendocrine hormones such as leptin, and ghrelin are the probable reasons of this negative association.	26667121
Inflammation, Anorexia	Altered Intercellular Communication	Chronic inflammation of the stomach that results in the loss of appetite and, dysregulation of neuroendocrine hormones such as leptin, and ghrelin are the probable reasons of this negative association.	26667121
Inflammation	Altered Intercellular Communication	We found a loss of CD4(+) T cell subset balance that was likely to promote a higher state of inflammation in IA, which may exacerbate the disease through a positive feedback loop.	26667180
Inflammation	Altered Intercellular Communication	Cryopyrin-associated periodic syndrome (CAPS) is a heterogeneous group of diseases characterized by excessive IL-1b release resulting in severe systemic and organ inflammation.	26667214
Inflammation, Atherosclerosis	Altered Intercellular Communication	Resistin is associated with inflammation, atherosclerosis and cardiovascular (CV) disease.	26667298
Inflammation, Malnutrition, Organ Dysfunction Scores	Altered Intercellular Communication	critical illness is characterized by a high degree of stress and accelerated degradation of proteins that cause malnutrition, systemic inflammation and organ dysfunction, with a significant association between albumin, ferritin and transferrin.	26667743
Inflammation, Ulcer	Altered Intercellular Communication	In fact, endoscopic, histological and endomicroscopic assessment demonstrated exacerbation of mucosal inflammation and ulcer formation upon anti-IL-6R therapy.	26668517
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Mechanistic studies revealed that tocilizumab treatment failed to suppress intestinal IL-6 production, impaired epithelial barrier function and induced production of pro-inflammatory cytokines such as TNF, IL-21 and IFN-g. Inhibition of IL-6 by tocilizumab had no clinical benefit in this patient with intractable ulcerative colitis and even led to exacerbation of mucosal inflammation.	26668517
Conjunctivitis, Strabismus	Altered Intercellular Communication	The MISS technique was similar to the fornix approach in the early postoperative period with respect to VA, conjunctival inflammation, and operating time in pediatric horizontal strabismus surgery.	26669420
Osteomyelitis, Inflammation, Fracture, Diabetes Mellitus	Altered Intercellular Communication	In this case report we present the dramatic course of a 64-year old female patient treated with five immediate post-extractive dental implants in the mandible, who developed osteomyelitis, which manifested initially as local peri-implant inflammation and progressed into a spontaneous jaw fracture, despite repeated surgical interventions and antibiotic courses over a 3-year period, until diabetes was diagnosed.	26669550
Pulmonary hemorrhage, Interstitial inflammation	Altered Intercellular Communication	Pulmonic interstitial inflammation gradually improved while resting the lung under ECMO support; however, effective ventilation volume decreased critically because a massive pulmonary hemorrhage occurred at 2 and 9 days after the initiation of ECMO.	26670317
Hematoxylin and eosin stain method, Inflammation, Synovitis	Altered Intercellular Communication	Two to three paraffin slides were used to quantify inflammation using haematoxylin and eosin (H&E) staining (synovitis score 0-9), and numbers of mast cells (per 10 high-power fields) using double immunofluorescence for CD117 and tryptase.	26671522
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Due to its crucial roles in inflammation and autoimmunity, STAT4 may have promise as an effective therapeutic target for axSpA.	26671920
Acute inflammation	Altered Intercellular Communication	It accurately differentiates patients who have chronic transmural (fibrotic) disease and thus may require an operation from those with acute inflammation, whose symptoms may improve with aggressive medical therapy alone.	26672581
Nephritis, Interstitial, Inflammation, Guinea (geographic area)	Altered Intercellular Communication	The granulomatous inflammation is rarely but often manifests as a form of a granulomatous interstitial nephritis (GIN) in the kidney.	26674186
Inflammation	Altered Intercellular Communication	Control of inflammation will inform the design of surface modification procedures to direct the immune response and enhance the success of implanted materials.	26675126
vascular inflammations, atherosclerotic	Altered Intercellular Communication	Chemokines appear to be involved in the development of these alterations given that they occur early in the atherosclerotic pathway as mediators of vascular inflammation.	26675251
Anemia, Sickle Cell, Inflammation, Thalassemia, Erythroblastosis, Fetal	Altered Intercellular Communication	Hemolytic diseases, such as sickle cell anemia and thalassemia, are characterized by enhanced release of hemoglobin and heme into the circulation, heme-iron loading of reticulo-endothelial system macrophages, and chronic inflammation.	26675351
Inflammation, Anemia, Sickle Cell	Altered Intercellular Communication	Taken together, our data suggest that therapeutic administration of hemopexin is beneficial to counteract heme-driven macrophage-mediated inflammation and its pathophysiologic consequences in sickle cell disease.	26675351
Inflammation, Hypomyelination, Neurologic Dysfunction	Altered Intercellular Communication	This leukodystrophy causes severe hypomyelination with progressive inflammation, leading to neurological dysfunctions and shortened life expectancy.	26676415
Sacroiliitis, Arthritis, Spondylitis, Enthesitis	Altered Intercellular Communication	Spondyloarthropathy (SpA) is a group of inflammatory conditions that include spondylitis, sacroiliitis, asymmetrical peripheral arthritis and enthesitis.	26677159
Inflammation, Asthma, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) and asthma describe inflammation of the upper and lower airway, respectively.	26678021
Inflammation	Altered Intercellular Communication	Our results suggest that NFkB, STAT1 and STAT3 underlie transcriptional changes and chronic inflammation in the aging human kidney.	26678048
Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Follicle-stimulating hormone is associated with non-alcoholic fatty liver disease in Chinese women over 55 years old.	26678239
Inflammation, Atrial Fibrillation by ECG Finding, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation has been associated with cardiovascular disease and the burden of atrial fibrillation (AF).	26678637
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Diagnostic nasal endoscopy is a routine measure of sinonasal inflammation in patients with chronic rhinosinusitis (CRS).	26678860
prostatitis	Altered Intercellular Communication	We sought to determine the influence of young adult-onset IM on the prostate by measuring prostate-specific antigen (PSA) as a marker of prostate inflammation/damage among U.S. military members.	26678984
Communicable Diseases, Inflammation, Prostate	Altered Intercellular Communication	To explore the specificity of our findings for prostate as opposed to systemic inflammation, we performed a post hoc comparison of other infectious disease cases without genitourinary involvement (n = 90) and controls (n = 220).	26678984
Inflammation, Prostatic Infection	Altered Intercellular Communication	These findings suggest that, in addition to rising because of prostate infection, PSA may also rise because of systemic inflammation, which could have implications for PSA interpretation in older men.	26678984
Inflammation, Necrosis	Altered Intercellular Communication	A previous oral biopsy described fibrinoid necrosis, mixed inflammation, and granulation tissue.	26679365
Saint Lucia	Altered Intercellular Communication	CC seems to be a more severe type of bowel inflammation and LC tends to occur earlier in life.	26679722
Architectural Distortion, Inflammation, Colitis	Altered Intercellular Communication	Histologic examination showed patchy chronic colitis with crypt architectural distortion and mild-moderate inflammation activity.	26680092
Inflammation, Primary malignant neoplasm, Malnutrition	Altered Intercellular Communication	Preoperative albumin-globulin ratio (AGR) reflects both malnutrition and systemic inflammation in cancer patients.	26681341
Inflammation, Neoplasms, Malignant Neoplasms	Altered Intercellular Communication	In particular, systemic inflammation has been reported to contribute to tumor progression and poor oncological outcome in various malignancies.	26681341
ARCN1 gene, Airway structure, Chronic Obstructive Airway Disease, Obstruction, Asthma	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) and asthma are both characterized by heterogeneous chronic airway inflammation and obstruction as well as oxidative stress (OS).	26681451
Barrett Esophagus, Esophagitis, Adenocarcinoma	Altered Intercellular Communication	Epidemiologic data regarding coffee and tea consumption and risk of esophageal inflammation, Barrett's esophagus (BE), and adenocarcinoma are sparse and inconclusive.	26681488
Inflammation, Chronic heart failure, Venous Engorgement, Congestive heart failure	Altered Intercellular Communication	The goal of this study was to measure the presence of pathogenic gut flora and intestinal permeability (IP) and their correlations with disease severity, venous blood congestion, and inflammation in patients with chronic heart failure (CHF).	26682791
Inflammation, Blood Circulation	Altered Intercellular Communication	Evidence suggests that translocation of gut flora and/or their toxins from the intestine to the bloodstream is a possible trigger of systemic CHF inflammation.	26682791
Inflammation, Venous Engorgement, Congestive heart failure	Altered Intercellular Communication	However, the relation between pathogenic gut flora and CHF severity, as well as IP, venous blood congestion as right atrial pressure (RAP), and/or systemic inflammation (C-reactive protein [CRP]), is still unknown.	26682791
Inflammation, Congestive heart failure, Yersinia , Campylobacter, Candida (fungus)	Altered Intercellular Communication	Compared with normal control subjects, the entire CHF population had massive quantities of pathogenic bacteria and Candida such as Campylobacter (85.3 +- 3.7 CFU/ml vs. 1.0 +- 0.3 CFU/ml; p < 0.001), Shigella (38.9 +- 12.3 CFU/ml vs. 1.6 +- 0.2 CFU/ml; p < 0.001), Salmonella (31.3 +- 9.1 CFU/ml vs 0 CFU/ml; p < 0.001), Yersinia enterocolitica (22.9 +- 6.3 CFU/ml vs. 0 CFU/ml; p < 0.0001), and Candida species (21.3 +- 1.6 CFU/ml vs. 0.8 +- 0.4 CFU/ml; p < 0.001); altered IP (10.2 +- 1.2 mg vs. 1.5 +- 0.8 mg; p < 0.001); and increased RAP (12.6 +- 0.6 mm Hg) and inflammation (12.5 +- 0.6 mg/dl).	26682791
Inflammation, Venous Engorgement, Congestive heart failure, Overgrowth, Candida (fungus)	Altered Intercellular Communication	This study showed that patients with CHF may have intestinal overgrowth of pathogenic bacteria and Candida species and increased IP associated with clinical disease severity, venous blood congestion, and inflammation.	26682791
Inflammation, Heart failure, Left ventricular diastolic dysfunction, Hypertrophy	Altered Intercellular Communication	The present study investigated whether systemic, low-grade inflammation of metabolic risk contributed to diastolic left ventricular (LV) dysfunction and heart failure with preseved ejection fraction (HFpEF) through coronary microvascular endothelial activation, which alters paracrine signalling to cardiomyocytes and predisposes them to hypertrophy and high diastolic stiffness.	26682792
Astrocytoma, Inflammation	Altered Intercellular Communication	Several microRNAs found to be up-regulated in pilocytic astrocytomas are predicted to target the ERK/MAPK and NF-kB signaling pathways as well as genes involved in senescence-associated inflammation and cell cycle control.	26682910
Inflammation, Signs and Symptoms, Respiratory, Failure (biologic function)	Altered Intercellular Communication	Reasons for failure to meet the diagnostic criteria in 75 cases were lack of radiographic evidence in 60/75; lack of evidence of inflammation in 42/75, and lack of respiratory signs or symptoms in 13/75; 35/75 (47%) of cases lacked evidence in two or more domains.	26683049
Inflammation, Periodontitis	Altered Intercellular Communication	The up-regulated genes in periodontitis were related to inflammation, wounding and defense response, and apoptosis, whereas down-regulated genes were related to extracellular matrix organization and structural support.	26686060
Periodontitis, Ulcerative Colitis, Cardiovascular Diseases, Refractory anemias, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Rheumatoid Arthritis	Altered Intercellular Communication	Here, we analyzed the global transcriptome of periodontitis and compared its gene expression profile with those of other inflammatory conditions, including cardiovascular disease (CVD), rheumatoid arthritis (RA), and ulcerative colitis (UC).	26686060
Osteoporosis	Altered Intercellular Communication	Osteoporosis is a chronic inflammatory condition that is characterized by the loss of bone mineral density (BMD).	26686359
Gout, Inflammatory, Rheumatoid Arthritis, Hereditary Diseases, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Interleukin-1b (IL-1b) is a key cytokine involved in inflammatory illnesses including rare hereditary diseases and common chronic inflammatory conditions as gout, rheumatoid arthritis, and type 2 diabetes mellitus, suggesting reduction of IL-1b activity as new treatment strategy.	26686385
Inflammation, Virus Diseases	Altered Intercellular Communication	Saffold virus was detected in the myocardium, lung tissue and blood of one child and was accompanied by histopathological inflammation in the heart and lungs, which was supportive of a viral infection.	26687438
Inflammation, Hypoxia	Altered Intercellular Communication	Comparable correlations were exhibited in the ex-vivo explant tissue between metabolism, p53, hypoxia, inflammation and angiogenesis (P < 0.05).	26688097
Inflammation, Decline in functional status, Renal mass	Altered Intercellular Communication	To investigate association of C-reactive protein (CRP), a marker of systemic inflammation, with renal functional decline patients undergoing partial nephrectomy (PN) for renal mass.	26688138
ARCN1 gene, Inflammation, Atherosclerosis	Altered Intercellular Communication	At the same time STEMI and COPD patients demonstrated higher CRP levels, which reflected the activity of inflammation--one of mechanisms of atherosclerosis development.	26688922
Inflammation, Biliary Fistula	Altered Intercellular Communication	The impacted stones and surrounding inflammation can lead to a biliobiliary fistula.	26688996
Inflammation, Squamous cell carcinoma of esophagus	Altered Intercellular Communication	Prognostic nomogram integrated systemic inflammation score for patients with esophageal squamous cell carcinoma undergoing radical esophagectomy.	26689680
Inflammation, Neoplasms	Altered Intercellular Communication	Growing evidence indicates that nomogram combined with the biomarkers of systemic inflammation response could provide more accurate prediction than conventional staging systems in tumors.	26689680
Inflammation, Spondylarthritis	Altered Intercellular Communication	At present, there are no studies that have established a microRNA (miRNA)-based signature profile in patients with radiographic axial spondyloarthritis (rad-axial SpA), and we hypothesized that these patients may have aberrantly expressed circulating miRNAs reflective of underlying disease and inflammation.	26689798
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Ageing, inflammation, and oxidative stress: final common pathways of cardiovascular disease.	26690751
Inflammation, Preterm premature rupture of membranes (disorder), Rupture	Altered Intercellular Communication	In women with preterm premature rupture of the membranes (PPROM), increased oxidative stress may accelerate premature cellular senescence, senescence-associated inflammation and proteolysis, which may predispose them to rupture.	26690900
Communicable Diseases, Hepatic inflammation	Altered Intercellular Communication	Future research should focus on interventions to promote abstinence and on treatments that suppress the hepatic inflammation without increasing susceptibility to infection.	26691209
Inflammation, Hypercholesterolemia, Thrombus	Altered Intercellular Communication	We conclude that smoking exacerbated the chronic inflammation induced by hypercholesterolemia, causing changes in his erythrocyte morphology and platelet activation, and suggest that ultrastructure here explains the clinical manifestations of the thrombotic state of this patient.	26691215
Drug-induced uveitis, Inflammatory abnormality of the eye	Altered Intercellular Communication	Drug-induced uveitis is a well-known effect of ocular inflammation that has been reported with many medications.	26692064
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	Ophthalmologists should keep in mind that drugs are always a possible cause of ocular inflammation in patients presenting with uveitis.	26692064
Gingivitis, Dental Plaque	Altered Intercellular Communication	The use of each of the three tested toothpastes caused a significant reduction in gingival inflammation and amount of plaque.	26694786
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Both are associated with inflammation, which may be partially triggered by oxidative stress, especially in cardiovascular disease.	26695510
Fatty Liver	Altered Intercellular Communication	Oxidative reactions are thought to play a role in the inflammatory condition called fatty liver.	26695550
Vasculitis	Altered Intercellular Communication	Orbital incisional biopsy suggested necrotising small vessel inflammation.	26695609
Inflammation, Gastritis, Chronic gastritis, Atrophic	Altered Intercellular Communication	Appropriate biopsy sampling is important for the classification of gastritis, yet the extent of inflammation and atrophy of different regions of the stomach with chronic gastritis have been addressed only in a few studies.	26697568
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	Non-Invasive Assessment of Inflammation and Treatment Response in Patients with Crohn's Disease and Ulcerative Colitis using Contrast-Enhanced Ultrasonography Quantification.	26697572
Crohn Disease, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Novel biological therapies in Crohn's disease (CD) or Ulcerative colitis (UC) require a proper follow-up for the assessment of bowel inflammation.	26697572
Inflammation, physiopathological, Obesity	Altered Intercellular Communication	Recent work has found that older adults with obesity and systemic inflammation have associated metabolic dysfunction but do not have associated lower lean mass or strength.	26698153
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Pathological findings showed only non-specific inflammation ; however, fever persisted postoperatively and blood test results showed no improvement.	26699892
orbit (eye disorders), Orbital Pseudotumor	Altered Intercellular Communication	IgG4-related orbital disease is a recognised cause for orbital inflammation.	26700191
Inflammation, Heart failure	Altered Intercellular Communication	Heart failure (HF) is associated with inflammation characterized by the formation of the inflammasome, which triggers maturation of inflammatory cytokines.	26700661
Inflammation, Rheumatoid Factor, immunoglobulin A	Altered Intercellular Communication	A significant decrease in IgG, IgA, IgM (p < 0.001 each), anticardiolipin antibodies IgG and IgM (p = 0.02), and beta-2 microglobulin (p = 0.004) was observed post-LT. HCV patients had higher IgG (p = 0.005), rheumatoid factor (p = 0.044) before LT; elevated IgM was associated with increased inflammation in the explant (p = 0.007).	26700965
Inflammation	Altered Intercellular Communication	Some immunological markers are associated with HCV recurrence and advanced inflammation on explant.	26700965
Inflammation, Muscle of orbit	Altered Intercellular Communication	Risk factors for an incomplete treatment response were male sex (P = .01) and inflammation extending to extraocular muscle (P = .01).	26701269
Inflammation	Altered Intercellular Communication	However, it may compromise aesthetics and contribute to gingival inflammation.	26701991
Inflammation	Altered Intercellular Communication	Given that B7-H3 expression on human monocytes and dendritic cells is enhanced by inflammatory cytokines, its potential inmmunoregulatory role at sites of inflammation has been suggested.	26702052
Airway structure, Virus Diseases, Herpes Simplex Infections	Altered Intercellular Communication	Th2 biased upper airway inflammation is associated with an impaired response to viral infection with Herpes simplex virus 1.	26702454
Inflammation, Acute infectious disease	Altered Intercellular Communication	We demonstrate for the first time in a human ex-vivo mucosal model that the inadequate response of CRSwNP may be associated with a deeper intrusion of viruses into the mucosal tissue, and may contribute to more and longer symptoms upon acute infection, but also to the persistence of inflammation in CRSwNP tissue.	26702454
Inflammation	Altered Intercellular Communication	This implies that mtDNA content might be a potential biomarker associated with oxidative stress and inflammation.	26702630
Acute inflammation	Altered Intercellular Communication	The topical NSAIDs ketorolac 0.4%, bromfenac 0.09%, and nepafenac 0.1% were effective for the reduction of postoperative inflammation following phacoemulsification.	26703278
Cataract, Pain Distress Question, Inflammatory abnormality of the eye	Altered Intercellular Communication	Sustained-release dexamethasone for the treatment of ocular inflammation and pain after cataract surgery.	26703279
Cataract, Inflammation, Pain Distress Question	Altered Intercellular Communication	Sustained-release dexamethasone provided elution of drug for up to 1 month after cataract surgery, providing clinically significant reductions in inflammation and pain.	26703279
Intraocular inflammation, Corneal edema, Edema	Altered Intercellular Communication	Postoperative CDVA, IOP, corneal edema, persistent intraocular inflammation, macular edema, and need for additional surgery were analyzed for the first postoperative year.	26703285
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation has shown to be an independent predictor of cardiovascular disease (CVD) and growing evidence suggests Non-Hispanic Blacks (NHBs) and certain Hispanic subgroups have higher inflammation burden compared to Non-Hispanic Whites (NHWs).	26703686
Inflammation, Psoriasis	Altered Intercellular Communication	Psoriasis has been shown to accompany systemic inflammation.	26704718
Psoriatic Juvenile Idiopathic Arthritis, Inflammation	Altered Intercellular Communication	In conclusion, serum CRP levels can be used to assess disease severity in Japanese psoriatic patients as a marker of systemic inflammation.	26704718
Communicable Diseases, Inflammation	Altered Intercellular Communication	It is potentially a better biomarker to follow post-operative inflammation or early infection after TKA.	26704797
Inflammation	Altered Intercellular Communication	Functional studies are warranted to understand how specific monocyte subsets and systemic inflammation may contribute to ADHF pathophysiology.	26705751
Inflammation, Disability or Permanent Damage, Ischemic stroke	Altered Intercellular Communication	Acute ischemic stroke, the most frequent cause of permanent disability in adults worldwide, results from transient or permanent reduction in regional cerebral blood flow and involves oxidative stress and inflammation.	26706245
Inflammation, Hypertension, CTCAE, Serum LDL cholesterol measurement, Obesity	Altered Intercellular Communication	In multivariate regression including male gender, hypertension, smoking status, HOMA score, obesity, LDL-cholesterol, lipoprotein (a) or markers of inflammation, serum PCSK9 remained an independent predictor of mean carotid IMT (P<0.001).	26706651
Conjunctivitis	Altered Intercellular Communication	The conjunctival inflammation was mild in most of the cases at postoperative day 4.	26706777
Pain Distress Question, Fibromyalgia	Altered Intercellular Communication	These findings provide further support for a disruption of dopaminergic neurotransmission in FMS and implicate DA as important neurochemical moderator of differences in pain perception in FMS patients with and without co-morbid depression.	26708319
Intraocular inflammation, Uveitis	Altered Intercellular Communication	Anterior uveitis is the most common type of intraocular inflammation.	26708737
Multiple Myeloma, PMF Regimen	Altered Intercellular Communication	The expression of fibrosis-, inflammation-, and angiogenesis-associated genes was analyzed in a total of 52 bone marrow biopsies: PMF patients (n = 14) before and after ASCT and, for control purposes, post-ASCT multiple myeloma patients (n = 14) and non-neoplastic hematopoiesis (n = 10).	26708839
Inflammation, Hypertrophy	Altered Intercellular Communication	Inflammation is associated with prostatic enlargement and resistance to 5a-reductase inhibitor (5ARI) therapy.	26709083
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Activation of the nuclear factor-kappa B (NF-kB) pathway is linked to both inflammation and ligand-independent prostate cancer progression.	26709083
Waldenstrom Macroglobulinemia, Immunoglobulin G4-Related Disease	Altered Intercellular Communication	IgG4 disease has been characterised by lymphoplasmacytic inflammation, rich in IgG4 plasma cells, elevated serum IgG4 and clinical improvement with steroid therapy.	26710480
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) may influence not only abdominal fat, but also whole body adiposity, since it is associated with chronic inflammation and disability.	26710499
Coronary artery ectasia, Inflammation	Altered Intercellular Communication	Gamma glutamyltransferase, inflammation and cardiovascular risk factors in isolated coronary artery ectasia.	26711537
Pain Distress Question, Inflammation, Intervertebral Disc Degeneration	Altered Intercellular Communication	Our current study strongly supports the potential of thalidomide for the treatment of pain and inflammation in degenerative disc disease.	26711561
Parkinson Disease, Inflammation, palladium	Altered Intercellular Communication	Parkinson's disease (PD) is characterised by low-level systemic inflammation, which may be at least partly due to pathophysiological activation of immunity.	26711571
Inflammation	Altered Intercellular Communication	A high proportion of older people is infected with cytomegalovirus (CMV), which acts as a chronic antigenic stressor that could also contribute to increased inflammation.	26711571
Inflammation, Lesion of retina	Altered Intercellular Communication	Ophthalmic examination a month and a half later showed almost all retinal lesions had disappeared and inflammation markers had returned to normal.	26711674
Breast Carcinoma	Altered Intercellular Communication	Systemic Correlates of White Adipose Tissue Inflammation in Early-Stage Breast Cancer.	26712688
Mastitis	Altered Intercellular Communication	In cohorts 1 and 2, breast WAT inflammation was detected in 52 of 100 (52%) and 52 of 127 (41%) patients, respectively.	26712688
Mastitis, Hyperlipidemia, Hypertension, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	In cohort 2, breast WAT inflammation was associated with hyperlipidemia, hypertension, and diabetes (P < 0.05).	26712688
Mastitis, Inflammation	Altered Intercellular Communication	Compared with patients without breast WAT inflammation, the adjusted HR for dRFS was 1.83 (95% CI, 1.07-3.13) for patients with inflammation.	26712688
Inflammation, Breast Carcinoma, Metabolic Syndrome X	Altered Intercellular Communication	WAT inflammation, a clinically occult process, helps to explain the relationship between metabolic syndrome and worse breast cancer prognosis.	26712688
Colorectal Carcinoma	Altered Intercellular Communication	Prognostic Inflammation Score in Surgical Patients with Colorectal Cancer.	26713054
Inflammation, HIV Infections	Altered Intercellular Communication	Recent studies suggest that increased immune activation and inflammation may contribute to excess risk for CVD in the context of HIV infection.	26713505
Inflammation, Demographics Domain, Degenerative polyarthritis, Obesity, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Obesity is a state of chronic inflammation that is associated with insulin resistance and type 2 diabetes mellitus (DM), as well as an increased risk of osteoarthritis (OA).	26713606
Degenerative polyarthritis, Inflammation, Tumor necrosis	Altered Intercellular Communication	This study was undertaken to define the links between obesity-associated inflammation, insulin resistance, and OA, by testing the hypotheses that 1) tumor necrosis factor (TNF) is critical in mediating these pathologic changes in OA, and 2) insulin has direct effects on the synovial joint that are compromised by insulin resistance.	26713606
Inflammation, Endotoxemia, diabetic	Altered Intercellular Communication	Our data indicate that diabetic HD-patients are particularly prone to splanchnic ischemia and might therefore have an increased risk for bacterial translocation, endotoxemia and systemic inflammation.	26713734
Degenerative polyarthritis, Inflammation, Hypertension, CTCAE, Obesity	Altered Intercellular Communication	Participants with OA had more potential CVD risk factors, including obesity, hypertension, high levels of low-density lipoprotein, greater severity of inflammation, and worse renal function, than did those without OA.	26714002
Airway structure, Asthma	Altered Intercellular Communication	We sought to compare coagulation and fibrinolysis parameters between healthy subjects and patients with mild, severe, and prednisolone-dependent asthma under stable conditions and to investigate whether hemostatic markers correlate with airway inflammation.	26714414
Weight Gain, Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Association of weight gain with coronary artery disease, inflammation and thrombogenicity.	26714821
Weight Gain, Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Little is known about association of long-term weight gain to development of coronary artery disease (CAD), inflammation and thrombogenicity.	26714821
Weight Gain, Inflammation	Altered Intercellular Communication	Our data suggest that maximal weight gain since age 17 years is associated with heightened thrombogenicity, inflammation and a poorer lipid profile but not an increased risk for severe CAD development.	26714821
Necrotizing granulomatous inflammation, Lesion of breast	Altered Intercellular Communication	Histologic examination of the palatal and breast lesions showed chronic granulomatous inflammation.	26714880
Inflammation, Neoplasms	Altered Intercellular Communication	Moreover, supernatant from tumor B cells suppressed T cell inflammation.	26715281
Inflammation, Disease	Altered Intercellular Communication	Although both diseases have been linked with systemic inflammation, studies on their potential bidirectional association are lacking.	26715401
Inflammation	Altered Intercellular Communication	This case report describes a 16-month-old boy of Hispanic/African American ethnicity who had extensive inflammation of and discharge from his right ankle.	26715611
Inflammation, Refractory anemias, Rheumatoid Arthritis, Inflammatory disorder, Disability	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease characterized by synovial inflammation and joint disability.	26716989
Refractory anemias, Inflammation	Altered Intercellular Communication	Curcumin is known to be effective in ameliorating joint inflammation in RA.	26716989
Shock, Inflammation, Damage, Septic Shock	Altered Intercellular Communication	Plasma Nuclear and Mitochondrial DNA Levels, and Markers of Inflammation, Shock, and Organ Damage in Patients with Septic Shock.	26717107
Shock, Inflammation, Damage, Septic Shock	Altered Intercellular Communication	Our aim was to determine whether plasma levels of nDNA and mtDNA are related to the markers of inflammation, severity of shock, and organ damage in septic shock patients.	26717107
Sepsis, Inflammation, Endotoxemia	Altered Intercellular Communication	Moreover, we investigated the relationship between plasma levels of nDNA/mtDNA and inflammatory cytokines during experimental human endotoxemia, a model of systemic inflammation in humans in vivo mimicking some of the hallmarks of early sepsis.	26717107
methyldopa, Inflammation, Limited stage (cancer stage)	Altered Intercellular Communication	Consistent with other evidence supporting the role of inflammation and the immune system in AMD pathogenesis, AAbs were identified in AMD sera, including early-stage disease.	26717306
Inflammation, Periodontitis, Chronic Kidney Diseases	Altered Intercellular Communication	Sources of chronic systemic inflammation (including periodontitis) may be important contributors to mortality in patients with CKD.	26717883
Autoimmune Diseases, Inflammation, Malignant Peripheral Nerve Sheath Tumor, Atherosclerosis	Altered Intercellular Communication	It is discussed if chronic inflammation in relation to autoimmunity and atherosclerosis might elicit mutations in the hematopoietic stem cell resulting in MPNs, or whether this association actually reflects a long-lasting pre-MPN-diagnosis phase, in which the MPN-disease per se contributes to a chronic inflammatory state and immune deregulation.	26718091
Communicable Diseases, Inflammation	Altered Intercellular Communication	Non-typeable Haemophilus influenzae (NTHi) is a human restricted commensal and pathogen that elicits inflammation by adhering to and invading airway epithelia cells: transcytosis across these cells can result in systemic infection.	26718097
Intraocular inflammation	Altered Intercellular Communication	In this case, its inert nature did not cause any further intraocular inflammation.	26718222
Inflammation, FBN1 gene, Disease remission, Granulomatosis, Subglottic stenosis, Systemic Vasculitis	Altered Intercellular Communication	Subglottic stenosis (SGS) in granulomatosis with polyangiitis (GPA) may result from active disease or from chronic recurrent inflammation.	26718390
Inflammation, Diabetic Retinopathy, GDC Disease Response Terminology	Altered Intercellular Communication	Inflammation plays an important role in the pathogenesis of diabetic retinopathy (DR).	26718887
Weight Gain, Inflammation	Altered Intercellular Communication	The findings suggest that weight gain in adulthood is associated with low-grade inflammation in late midlife.	26718895
Airway structure, ARCN1 gene, Inflammation	Altered Intercellular Communication	Because airway inflammation is a hallmark of COPD, it has been proposed that measuring exhaled nitric oxide, a marker of inflammation, in exhaled breath condensate could prove to be an inexpensive and efficient method to detect COPD in outpatient settings.	26718918
ARCN1 gene, Inflammation	Altered Intercellular Communication	The findings of this study do not support use of eNO as a biomarker of inflammation in diagnosis and management of COPD.	26718918
Refractory anemias, Inflammation	Altered Intercellular Communication	These findings emphasise the adverse effects of chronic inflammation on the durability of PCI and provide further support for aggressive anti-inflammatory treatment in patients with RA.	26719360
Inflammation	Altered Intercellular Communication	The ION-enlarged group showed a higher percentage of the patients with diffuse inflammation (66.7%, p<0.001).	26719493
Inflammation, Hypertrophy	Altered Intercellular Communication	Repetitive inflammation (recurrence >=3) with steroid dependency was found only in 19.5% patients without ION enlargement but in 66.7% patients with ION enlargement.	26719493
Inflammation	Altered Intercellular Communication	Further insights in understanding their role in corneal wound inflammation may help design new therapeutic strategies.	26720440
Inflammation, Postoperative Hemorrhage	Altered Intercellular Communication	In conclusion, postoperative bleeding is reduced in patients who continued aspirin, likely due to a reduction in postoperative inflammation.	26721653
Ruptured behavior, Inflammation, Cholesteatoma	Altered Intercellular Communication	We sought to investigate if second-look procedures after endoscopic-assisted surgery could safely be performed only in children at a high risk of residual disease (extensive inflammation, spontaneously ruptured or fragmented cholesteatoma, residual disease intentionally left).	26721891
Inflammatory Bowel Diseases, Inflammation, Abdominal Pain	Altered Intercellular Communication	In a post hoc analysis of pooled data from two randomized controlled trials we assessed the association between demographic data (gender, age, smoking habits, family history of inflammatory bowel disease), clinical variables (duration of symptoms, mean number of stools/watery stools per day, abdominal pain, clinical remission) and histological data (thickness of the collagen band, inflammation of the lamina propria, total numbers of intraepithelial lymphocytes, degeneration).	26721941
Inflammation, Mood Disorders	Altered Intercellular Communication	The role of inflammation in mood disorders has received increased attention.	26721949
Depression, CTCAE	Altered Intercellular Communication	Glucocorticoid Receptors, Brain-Derived Neurotrophic Factor, Serotonin and Dopamine Neurotransmission are Associated with Interferon-Induced Depression.	26721949
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Patients with end stage renal failure (ESRD) report low quality of life and inflammation may be one of the contributing factors.	26722560
Inflammation, Metabolic Diseases	Altered Intercellular Communication	Further adjustment for metabolic disease slightly reduced the associations while adjustment for inflammation markedly reduced the associations.	26724528
Inflammation, Metabolic Diseases	Altered Intercellular Communication	In older adults, higher resistin levels are associated with CVD events independently of clinical risk factors and metabolic disease markers, but markedly attenuated by inflammation.	26724528
Inflammation, Calcinosis	Altered Intercellular Communication	These alterations correlated with oxidative stress, inflammation, senescence and calcification (all p < 0.05).	26724531
Inflammation, Calcinosis	Altered Intercellular Communication	ZMPSTE24 silencing in native VSMCs recapitulated the mutant LMNA- and PI-induced accumulation of farnesylated prelamin A, oxidative stress, inflammation, senescence and calcification.	26724531
Inflammation	Altered Intercellular Communication	In multivariate analysis, parameters that affected gastric emptying T 1/2 time were found as serum gastrin level (OR 1.002, 95 % CI 1.001-1.004, p < 0.001, chronic inflammation (OR 3.689, 95 % CI 1.44-9.39, p < 0.001), and increase in the degree of the atrophy of the gastric mucosa (OR 8.96, 95 % CI 2.98-26.93, p < 0.001).	26725066
Craniocerebral Trauma, Inflammation	Altered Intercellular Communication	However in animal models brain inflammation, which can be initiated by head trauma, has been shown to produce PD-like effects.	26725141
palladium, Inflammation	Altered Intercellular Communication	Furthermore, animal studies have found that early life inflammation in particular is of relevance for PD pathology.	26725141
Inflammation, Pulpitis	Altered Intercellular Communication	Differentiation between reversible pulpitis (savable pulp) and irreversible inflammation of the pulp tissue (nonsavable pulp) based only on clinical and radiographic diagnoses has proven to be difficult.	26725178
Inflammation, Depression, CTCAE, HIV Infections	Altered Intercellular Communication	These findings suggest that SSRI treatment, independent of depression status, downregulates HIV receptor and coreceptor expression and may reduce susceptibility of immune cells to HIV infection and decrease inflammation.	26725193
Inflammation, Impaired cognition, Cerebral Small Vessel Diseases, Atherosclerosis	Altered Intercellular Communication	Inflammation is implicated in atherosclerosis, cerebral small-vessel disease (SVD) as well as cognitive impairment.	26725994
Renal Insufficiency, Reperfusion Injury, Kidney Failure, Acute, Nephritis	Altered Intercellular Communication	When subjected to ischemia-reperfusion (IR)-induced AKI, AIM-deficient mice exhibited abrogated debris clearance and persistent renal inflammation, resulting in higher mortality than wild-type (WT) mice due to progressive renal dysfunction.	26726878
Sepsis, Inflammation, Traumatic injury	Altered Intercellular Communication	In severe trauma, overwhelming systemic inflammation can result in additional damage and the development of complications, including sepsis.	26727089
Sepsis, Inflammation	Altered Intercellular Communication	Transcriptome profiling of the discovery set revealed the strongest changes between patients with either systemic inflammation or sepsis in gene expression of the heme degradation pathway.	26727089
Sepsis, Inflammation	Altered Intercellular Communication	Upregulation of HP was associated with the severity of systemic inflammation and the development of sepsis.	26727089
palladium, Inflammation	Altered Intercellular Communication	Serum and drained dialysate concentrations of VEGF in PD patients were connected with poorer metabolic profile, while the role of inflammation and treatment agents should be studied further.	26727866
Chronic Kidney Diseases	Altered Intercellular Communication	Intact FGF23 and a-Klotho during acute inflammation/sepsis in CKD patients.	26728476
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	High FGF23 and low a-Klotho levels associate with systemic inflammation and reduced nitric oxide (NO) bioavailability, but the dynamics of this relationship in patients with CKD has not been investigated.	26728476
Sepsis, Inflammation, Chronic kidney disease mineral and bone disorder, Chronic Kidney Diseases	Altered Intercellular Communication	We sequentially measured serum intact FGF23 and carboxyl-terminal (iFGF23, cFGF23), the iFGF23/cFGF23 ratio, aKlotho, biomarkers of inflammation (hs-CRP, IL-6 and TNF-a) and sepsis (procalcitonin), nitrotyrosine (reflecting NO synthesis and oxidative stress), serum iron and ferritin and CKD-MBD biomarkers, PTH, 25(OH)VD, 1,25(OH)2 VD at peak of intercurrent sepsis and after complete resolution in a series of 17 patients with CKD.	26728476
Communicable Diseases	Altered Intercellular Communication	At peak infection, biomarkers of inflammation/sepsis, ferritin and nitrotyrosine were all very high (all P < 001) and declined towards the normal range thereafter (P < 001).	26728476
Sepsis, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	iFGF23 downregulation and a-Klotho upregulation during acute sepsis may participate into the counter-regulatory response to severe inflammation in CKD patients with sepsis.	26728476
Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	This was associated with less renal cortical fibrosis and interstitial inflammation compared to nontransplanted mice as shown by reduction in murine CD4, CD68, and CD45.2 cells.	26728561
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The cardiovascular magnetic resonance study (CMR) included evaluation of function, inflammation and fibrosis.	26728774
Inflammation, Metabolic Syndrome X, MS gene	Altered Intercellular Communication	Inflammation plays an important role in the pathogenesis of metabolic syndrome (MS).	26728949
Inflammation, FAM126A gene	Altered Intercellular Communication	Recently, neutrophil-to-lymphocyte ratio (NLR), a marker of systemic inflammation that is associated with tumor-associated macrophages (TAMs), was suggested to be a prognostic marker of HCC treated with RFA.	26729319
Inflammation, Mycobacterium Infections	Altered Intercellular Communication	Histology of his pleural biopsy identified multiple non-confluent necrotising granulomatous inflammation with very occasional acid-alcohol-fast bacilli-like organisms, highly suspicious for mycobacterial infection.	26729824
ARCN1 gene, Eosinophilic inflammation	Altered Intercellular Communication	COPD patients with increased airway eosinophilic inflammation show a favorable response to inhaled corticosteroids (ICS) in combination with a long-acting bronchodilator.	26730185
ARCN1 gene	Altered Intercellular Communication	Cigarette smoke-induced lung inflammation in COPD mediated via LTB4/BLT1/SOCS1 pathway.	26730186
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Long-term cigarette smoke exposure induced SOCS1 degradation and LTB4 accumulation, which was associated with emphysema and inflammation.	26730186
Intraocular inflammation	Altered Intercellular Communication	No evidence of additional intraocular inflammation was present.	26731215
Fibrosis Assessment, Hepatitis, Chronic, Splenomegaly	Altered Intercellular Communication	Schistosoma eggs cause chronic liver inflammation and a complex disease characterized by hepatic fibrosis (HF) and splenomegaly (SplM).	26731721
Schistosomiasis, Inflammation	Altered Intercellular Communication	FOXP3+ Tregs could regulate inflammation, but it is unclear where these cells are produced and what roles they play in human schistosomiasis.	26731721
Schistosomiasis, Inflammation	Altered Intercellular Communication	In most cases, Tregs migrate to the Th1-infiltrated liver and the lower levels of CXCR3+ Tregs in the blood of patients with severe schistosomiasis suggest that decreases in Treg migration sites of inflammation may aggravate the disease.	26731721
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Fine particles, genetic pathways, and markers of inflammation and endothelial dysfunction: Analysis on particulate species and sources.	26732377
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Our findings suggest that particles derived from oil combustion may be associated with inflammation and endothelial dysfunction, and it is likely that oxidative stress plays a role in the associations.	26732377
methyldopa, Inflammation	Altered Intercellular Communication	Age-related macular degeneration (AMD) risk variants in the complement system point to the important role of immune response and inflammation in the pathogenesis of AMD.	26733291
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Adiponectin, markers of subclinical inflammation and nerve conduction in individuals with recently diagnosed type 1 and type 2 diabetes.	26733478
Endothelial dysfunction	Altered Intercellular Communication	These findings suggest that positive and negative psychological factors affect DNA methylation of selected genes involved in chronic immune/inflammatory processes and inflammation-related endothelial dysfunction.	26733571
Vaginitis	Altered Intercellular Communication	The cause of the adhesion was considered to be vaginal inflammation induced by anticancer agents themselves.	26735150
Inflammation, Cerebral dysfunction	Altered Intercellular Communication	Systemic inflammation on postnatal days 21 and 28 and indicators of brain dysfunction 2years later among children born before the 28th week of gestation.	26735345
Inflammation, Mental disorders	Altered Intercellular Communication	Systemic inflammation during the first two postnatal weeks in extremely preterm newborns (<28weeks gestation) has been associated with an increased risk of neurodevelopmental dysfunctions.	26735345
Inflammation	Altered Intercellular Communication	Little is known, however, about the relationship between systemic inflammation during the third and fourth postnatal weeks and subsequent development.	26735345
Inflammation, Cerebral ventriculomegaly, Microcephaly	Altered Intercellular Communication	Top quartile concentrations of CRP, SAA, IL-6, TNF-R2, IL-8, and ICAM-1 were associated with mental development index (MDI) of the Bayley-II<55, while top quartile concentrations of CRP, TNF-a (inversely), IL-8, and ICAM-1 were associated with psychomotor development index (PDI)<55 CONCLUSION: Extremely preterm newborns who had systemic inflammation during the third and fourth postnatal weeks were at increased risk of ventriculomegaly during the months after birth, and of microcephaly, and low Bayley Scale scores at 2years old.	26735345
Inflammation	Altered Intercellular Communication	A severe local inflammation with raised CRP levels, however, might affect accurate 18F-FDG quantification in CRC tumors.	26735530
Cessation of life, Inflammation	Altered Intercellular Communication	Pathway analysis demonstrated that these genes are involved in cell death, inflammation, cardiac remodeling and nervous system function.	26735598
Alzheimers Disease", Inflammation	Altered Intercellular Communication	Alzheimer disease, inflammation, and novel inflammatory marker: resistin.	26738345
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation may play an important role in Alzheimer disease (AD) pathogenesis.	26738345
Inflammation	Altered Intercellular Communication	The fractional exhaled nitric oxide concentration (FENO) is used as a noninvasive biomarker for asthmatic inflammation.	26738370
nervous system disorder	Altered Intercellular Communication	This presynaptic high-voltage-gated channel couples neuronal excitation to the vesicular release of neurotransmitter and is implicated in several neurologic disorders.	26739101
Hepatitis, FAM126A gene	Altered Intercellular Communication	Our data suggest that CTGF could be involved in oncogenic pathways promoting non-viral HCC associated with metabolic risk factors via induction of liver inflammation and is expected to be a novel HCC risk biomarker and potential therapeutic target.	26739296
Inflammation, Lymphohistiocytosis, Hemophagocytic	Altered Intercellular Communication	Hemophagocytic lymphohistiocytosis (HLH) is a fatal clinical syndrome characterized by excessive immune activation and inflammation.	26739581
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	As a surrogate marker of systemic inflammation, the lymphocyte-to-monocyte ratio (LMR) is an independent prognostic factor for various malignancies.	26740116
Inflammation, Encephalomyelitis, Acute Disseminated	Altered Intercellular Communication	Of 105,557 patients screened, 774 (0.7%) fulfilled entry criteria for CNS infection/inflammation, with 114 cases ascertained as ADEM.	26741581
Inflammation, Encephalomyelitis, Acute Disseminated	Altered Intercellular Communication	Parechoviruses were detected in 2.5% of patients with CNS infection/inflammation, including 1 case fulfilling ADEM case criteria with the highest level of diagnostic certainty.	26741581
Inflammation	Altered Intercellular Communication	Inflammation is an important reaction underlying lumbar disc herniation (LDH).	26742440
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	It plays important roles in chronic inflammation and autoimmune diseases.	26742440
Inflammation, Pain Distress Question	Altered Intercellular Communication	Enhanced production of IL-21 in disc tissues of LDH patients was also confirmed using immunohistochemical analyses.We concluded that inflammation was responsible for the pain associated with LDH, and that increased IL-21 expression may be associated with the pathogenesis of LDH.	26742440
Inflammation, Hepatitis B	Altered Intercellular Communication	Pre-vaccination inflammation and B-cell signalling predict age-related hyporesponse to hepatitis B vaccination.	26742691
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Inflammation and fibrosis were analysed with histological criteria and SPK1 expression was determined by individual immunohistochemical staining.	26742972
Inflammatory abnormality of the eye	Altered Intercellular Communication	Despite the aggressive course of ocular inflammation, her visual acuity remained good.	26743185
Inflammation, Periodontal Diseases	Altered Intercellular Communication	Cyclooxygenase-2 and matrix metalloproteinase-9 expressions correlate with tissue inflammation degree in periodontal disease.	26743292
Gingivitis, Inflammation, Periodontitis, Periodontal Diseases, Chronic inflammatory disorder	Altered Intercellular Communication	The aim of our study was to correlate the intensity of inflammation with MMP-9 and Cox-2 expression in the periodontal tissue of patients with chronic inflammatory disease (gingivitis and chronic periodontitis) in order to determine the role of these two biomarkers in the progression of periodontal disease.	26743292
Inflammation	Altered Intercellular Communication	In these three groups, we graded the intensity of inflammation in the lamina propria and the immunohistochemical expression of MMP-9 and Cox-2.	26743292
Gingivitis, Inflammation, Periodontitis	Altered Intercellular Communication	The presence of a large number of inflammatory cells in the lamina propria in patients with gingivitis or chronic periodontitis (Groups II and III) correlated with the clinically diagnosed inflammation of the gingival tissue.	26743292
Gingivitis, Inflammation, Periodontitis	Altered Intercellular Communication	The expression of Cox-2 in periodontitis was also higher compared to gingivitis (p=0.05, Mann-Whitney U-test) and to controls (p=0.001, Mann-Whitney U-test).The inflammation score could be positively correlated to the MMP-9 and Cox-2 expression scores at the overall study group, but not separately on gingivitis and periodontitis patients.	26743292
Communicable Diseases, Inflammation	Altered Intercellular Communication	Infection or inflammation (a1-acid glycoprotein >12 g/l) was present in 302 % (n 184) of children.	26743501
Inflammation, Peritubular Capillaritis Assessment, Glomerulitis (disorder)	Altered Intercellular Communication	The key lesions in antibody-mediated kidney transplant rejection (ABMR) are microcirculation inflammation (peritubular capillaritis and/or glomerulitis lesions, abbreviated "pg") and glomerular double contours (cg lesions).	26743766
Inflammation, disc disorder	Altered Intercellular Communication	These findings suggest that LBP subjects have low-grade systemic inflammation, and biochemical profiling of circulating cytokines may assist in refining personalized diagnoses of disc diseases.	26743937
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Natural IgM antibodies (nIgM) are polyreactive autoantibodies that have diverse roles in regulating autoimmunity, systemic inflammation and removal of oxidized low-density lipoproteins (oxLDL).	26744098
Inflammation, Microalbuminuria, Cerebrovascular accident, Leukoencephalopathy, Chronic Kidney Diseases	Altered Intercellular Communication	The primary aim is to characterize the association between (1) baseline and incident stroke, white matter disease, estimated glomerular filtration rate (eGFR), inflammation, microalbuminuria, and dialysis initiation and (2) cognitive decline over 3 years in a CKD cohort with a mean eGFR<45 mL/min/1.73 m(2).	26744128
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Baseline as well as cumulated values of markers reflecting systemic inflammation, lymphocyte activation, endothelial dysfunction and oxidative stress were not correlated with carotid subclinical atherosclerosis.	26744355
Amyotrophic Lateral Sclerosis, Inflammation, Pathology	Altered Intercellular Communication	In amyotrophic lateral sclerosis, we have shown that transplanted spinal neural stem cells (NSCs) integrate into the spinal cord, form synapses with the host, improve inflammation, and reduce disease-associated pathologies.	26744412
Thyroiditis	Altered Intercellular Communication	A correlation between globus pharyngeus and thyroid gland inflammation has been mentioned in previous studies.	26744863
Inflammation, Swelling, Contusions	Altered Intercellular Communication	Other injection site reactions included nodules (38%), swelling (28%), bruising (16%), scar tissue (8%) and inflammation (7%).	26744896
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Our results add to the evidence that chronic inflammation is a candidate mechanism at the crossroad between MetS and BPH/LUTS, and the presence of elevated MPV may serve as a predictor of MetS-induced inflammation in the progression of BPH/LUTS.	26745140
Inflammation	Altered Intercellular Communication	They are shed from nearly every activated or preapoptotic cell and may exhibit biologic activities in inflammation or apoptosis settings.	26746017
Inflammation, Arthritis	Altered Intercellular Communication	GPs mainly used classical signs of inflammation to diagnose inflammatory arthritis.	26747844
Inflammation	Altered Intercellular Communication	Background Endocan (endothelial cell-specific molecule-1) is a proteoglycan and plays an important role in angiogenesis and inflammation.	26748103
Gastroesophageal reflux disease, Inflammation, Autonomic neuropathy	Altered Intercellular Communication	The results are consistent with a growing body of evidence that cardiac autonomic neuropathy as measured by HRV is associated with gastro-esophageal reflux disease and also suggest that successful treatment of the inflammation can lead to reversal of the deterioration of autonomic tone associated with that inflammation.	26748487
Degenerative polyarthritis, Pain Distress Question, Inflammation	Altered Intercellular Communication	In patients with knee OA, serum hsCRP is associated with knee BML scores and, to a lesser extent, pain both cross-sectionally and longitudinally, suggesting that inflammation is linked with BMLs and their associated pain.	26748954
Inflammation, OED gene	Altered Intercellular Communication	Gene ontology enrichment revealed LAF in OEH was mostly due to changes in inflammation, cell cycle regulation and apoptosis, while in OED was due to inflammation, angiogenesis and extracellular matrix remodelling.	26749103
Inflammation, Coombs positive hemolytic anemia	Altered Intercellular Communication	The blood test shows Coombs-positive hemolytic anemia and inflammation.	26749635
ARCN1 gene, Chronic Obstructive Airway Disease, Pulmonary Emphysema, Airway structure	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease with small airway inflammation and emphysema.	26749913
Achondroplasia	Altered Intercellular Communication	Dwarfism may be due to achondroplasia or hormonal growth disorders.	26750695
Kidney Failure, Chronic, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	To assess the contribution of TMAO to inflammation and mortality in chronic kidney disease (CKD) patients ranging from mild-moderate to end-stage disease and 1) associations with glomerular filtration rate (GFR) 2) effect of dialysis and renal transplantation (Rtx) 3) association with inflammatory biomarkers and 4) its predictive value for all-cause mortality.	26751065
Upper Respiratory Infections	Altered Intercellular Communication	Although respiratory reactions following ingestion of ASA and other nonsteroidal anti-inflammatory drugs (NSAIDs) are considered a hallmark of the condition, respiratory inflammation persists despite patients' avoidance of NSAIDs.	26751262
TNF protein, human, Tumor necrosis, Inflammation	Altered Intercellular Communication	The C-reactive protein (CRP) and the tumor necrosis factor-alpha (TNF-a) are considered markers of inflammation and have been shown to predict the risk of incident cardiovascular events.	26751459
Inflammation, Mean mid-expiratory flow rate, Anemia	Altered Intercellular Communication	MMFR combined with non-nutritional approaches addressing anemia and inflammation should be further investigated.	26751473
Pain in elbow	Altered Intercellular Communication	Humeral epicondylitis, a relatively common disease, is classified among inflammatory conditions of soft tissues and is frequently associated with elbow pain.	26751747
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Natural killer (NK) cells are swiftly mobilized to organs targeted by autoimmunity and typically undergo numerical contraction when inflammation wanes.	26752157
ARCN1 gene	Altered Intercellular Communication	The MIF Antagonist ISO-1 Attenuates Corticosteroid-Insensitive Inflammation and Airways Hyperresponsiveness in an Ozone-Induced Model of COPD.	26752192
ARCN1 gene, AHR wt Allele	Altered Intercellular Communication	MIF and HIF-1a levels are elevated in COPD BAL macrophages and inhibition of MIF function blocks corticosteroid-insensitive lung inflammation and AHR.	26752192
Inflammation, Centers for Disease Control and Prevention (U.S.)	Altered Intercellular Communication	Resolution of tendinoses reversed the inflammation causing the CDC.	26752490
Multiple Organ Failure, Inflammation, Pancreatitis, Organ dysfunction syndrome, Cessation of life	Altered Intercellular Communication	Acute pancreatitis (AP) is a common and devastating inflammatory condition of the pancreas that is considered to be a paradigm of sterile inflammation leading to systemic multiple organ dysfunction syndrome (MODS) and death.	26752518
Multiple Organ Failure, Inflammation, Pancreatitis, Organ dysfunction syndrome, Cessation of life	Altered Intercellular Communication	Acute pancreatitis (AP) is a common and devastating inflammatory condition of the pancreas that is considered to be a paradigm of sterile inflammation leading to systemic multiple organ dysfunction syndrome (MODS) and death.	26752518
ARCN1 gene, Lung Injury, Pneumonitis, Impaired	Altered Intercellular Communication	Mitochondrial iron chelation also alleviated CS-induced impairment of MCC, CS-induced pulmonary inflammation and CS-associated lung injury in mice with established COPD, suggesting a critical functional role and potential therapeutic intervention for the mitochondrial-iron axis in COPD.	26752519
Malignant Neoplasms	Altered Intercellular Communication	Modified inflammation-based score was identified as an independent predictor of malignancies in patients with pulmonary fGGOs.	26752624
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a key role in the pathophysiology of atherosclerosis.	26752692
Multiple polyps, Rhinosinusitis, Airway structure, Asthma, Respiration Disorders	Altered Intercellular Communication	Aspirin-exacerbated respiratory disease (AERD), formerly known as Samter's Triad, is a syndrome of airway inflammation characterized by rhinosinusitis with polyposis, asthma, and nonsteroidal anti-inflammatory drug (NSAID) intolerance.	26753248
Pain Distress Question, Inflammation, Swelling, Lymphedema, Disability	Altered Intercellular Communication	Lymphedema, typically presents symptoms of swelling, pain, inflammation, and itching, and it can generate, over the years, acute disability in the affected limbs.	26753640
Photoreceptor degeneration, Inflammation	Altered Intercellular Communication	Here, we identify IL-33 as a key regulator of inflammation and photoreceptor degeneration after retina stress or injury.	26755704
Electrocardiogram: myocardial infarction (finding), Myocarditis	Altered Intercellular Communication	We report the case of a 62-year-old woman with a history of ST-elevation myocardial infarction who underwent 68Ga-Pentixafor PET/CT for characterization of postinfarct myocardial inflammation.	26756098
Inflammation, Fracture	Altered Intercellular Communication	The local enhanced activity was associated with the development of clinical complications such as chest wall inflammation and rib fracture.	26756408
Alzheimers Disease", Inflammation	Altered Intercellular Communication	Cerebrospinal Fluid Alzheimer's Disease Biomarkers in Cerebral Amyloid Angiopathy-Related Inflammation.	26757185
Respiratory Distress Syndrome, Adult, Pneumonitis, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	Leukocyte-mediated pulmonary inflammation is a key pathophysiological mechanism involved in acute respiratory distress syndrome (ARDS).	26757701
Inflammation	Altered Intercellular Communication	Here, we approach this problem from an immunological perspective by examining CD19(+)CD24(hi)CD38(hi) B cells, an important participant in acute and chronic inflammation.	26758063
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Influence of pre-existing inflammation on the outcome of acute coronary syndrome: a cross-sectional study.	26758266
Inflammation, Acute Coronary Syndrome, Coronary Artery Disease, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation is a well-established risk factor for the development of coronary artery disease (CAD) and acute coronary syndrome (ACS).	26758266
Inflammation, Acute myocardial infarction, Angina, Unstable, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	The aim of this study was to determine if blood biomarkers of inflammation were associated specifically with acute myocardial infarction (MI) or unstable angina (UA) in patients with ACS.	26758266
Inflammation, Chest Pain, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	When adjusted for smoking, age, sex and duration of chest pain, concentrations of plasma biomarkers of inflammation (high-sensitivity C reactive protein>2 mg/L (OR=1.40 (1.00 to 1.96) and fibrinogen (p for trend=0.035)) analysed at admission were found to be associated with MI over UA, in an event of ACS.	26758266
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Our results show that, in patients with ACS, the blood cell profile and degree of inflammation at admission was associated with the outcome.	26758266
Inflammation	Altered Intercellular Communication	Furthermore, our data suggest that a pre-existing low-grade inflammation may dispose towards MI over UA.	26758266
Inflammation, Gastritis	Altered Intercellular Communication	Association between serum levels of high sensitive C-reactive protein and inflammation activity in chronic gastritis patients.	26758551
Inflammation, Gastritis	Altered Intercellular Communication	This study aimed to determine any relationship between high sensitive C-reactive protein (hs-CRP) and inflammation activity among patients with gastritis.	26758551
Inflammation	Altered Intercellular Communication	The relation between active inflammation and other variables was evaluated by logic link function model.	26758551
Inflammation	Altered Intercellular Communication	The prevalence of mild, moderate and severe inflammation activities was 66.5%, 23.8% and 9.6% respectively.	26758551
Inflammation	Altered Intercellular Communication	Relationship between hs-CRP and inflammation activities (p < 0.01) was significant.	26758551
Inflammation, Plaque, Amyloid, neuron death, Data types - Address	Altered Intercellular Communication	We aimed at deciphering the modifications occurring in vivo during the very early stages of AD, before the development of amyloid deposits, neurofibrillary tangles, neuronal death and inflammation.	26759118
Refractory anemias, Inflammation, Rheumatoid Arthritis, Infiltration	Altered Intercellular Communication	Synovial infiltration of monocytes is commonly associated with inflammation in rheumatoid arthritis (RA).	26759164
Refractory anemias, Inflammation	Altered Intercellular Communication	Toll-like receptors (TLRs) are innate sensors that recognize cell debris and microbial components in host, a process contributing to maintain chronic inflammation in RA.	26759164
Inflammation, Vascular Diseases, Muscle (organ)	Altered Intercellular Communication	In addition to being a fatal complication, clinicians should be aware of these complications, as immunosuppression used to control the muscular and cutaneous inflammation may not control the GI vasculopathy.	26759443
methyldopa, Inflammation, Apoptosis of neurons	Altered Intercellular Communication	Inflammation and oxidative stress are involved in age-related macular degeneration (AMD) and possibly associated with an activation of neuronal apoptosis inhibitor protein/class II transcription activator of the Major Histocompatibility Complex (MHC)/heterokaryon incompatibility/telomerase-associated protein 1, leucine-rich repeat or nucleotide-binding domain, leucine-rich repeat-containing family, and pyrin domain-containing 3 (NLRP3) inflammasome.	26760997
Inflammation, Toxic effect	Altered Intercellular Communication	RT can induce cytokine responses that could play a role in mediating radiation toxicity by increasing inflammation.	26761561
Inflammation, Bipolar Disorder	Altered Intercellular Communication	The Predictive Value of Depressive Symptoms for All-Cause Mortality: Findings From the PRIME Belfast Study Examining the Role of Inflammation and Cardiovascular Risk Markers.	26761713
Inflammation	Altered Intercellular Communication	The level of protein expression appears to be different between muscle, knee joint and serum, suggesting that inflammation is regulated differently within these tissues.	26762130
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	While IL-15 protein expression in the muscle was lower in the knee OA group, no correlation was found between the expression of IL-15 protein in the muscle, joint and serum, which suggests that inflammation is regulated differently within these tissues.	26762130
Sepsis, Respiratory Failure, diabetic	Altered Intercellular Communication	A case report of a 68-year-old male obese diabetic patient with an abscess of left femoral region, and diffuse inflammation of abdominal wall and genital region developing sepsis, respiratory and renal failure.	26762496
Inflammation, Ocular Motility Disorders	Altered Intercellular Communication	Blueberries have been recognized to possess protective properties from inflammation and various diseases, but not for eye and ocular disorders.	26762881
Inflammation, Dryness (characteristic)	Altered Intercellular Communication	Our findings demonstrate that PS protects human cornea from hyperosmolarity-induced inflammation and oxidative stress, suggesting protective effects of PS on dry eye.	26762881
Atrial Fibrillation, Inflammation	Altered Intercellular Communication	These results demonstrate for the first time a dependency of MPAs and CD11b expression on monocytes in the presence of AF and support the notion of a close relationship between AF, thrombogenesis and inflammation.	26763077
vascular inflammations, Vascular calcification	Altered Intercellular Communication	This study investigated noncoronary vascular calcification and its influence on changes in vascular inflammation.	26764069
vascular inflammations, Calcinosis	Altered Intercellular Communication	Finally, baseline calcification was related to changes in vascular inflammation.	26764069
vascular inflammations, Calcinosis, Vascular calcification	Altered Intercellular Communication	The presence of vascular calcification at baseline is associated with progressive calcification; in the carotid arteries, calcification appears to influence vascular inflammation.	26764069
Calcinosis, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is an inflammatory condition with calcification apparent late in the disease process.	26764069
Inflammation, Primary malignant neoplasm, vinyltriethoxysilane	Altered Intercellular Communication	In this prospective cohort study of 1,070 cancer patients, decreased serum albumin was a marker for risk of VTE and mortality, independent of kidney or liver function and inflammation markers.	26764252
Inflammation, Presenile dementia, Coronary heart disease, Cerebrovascular accident, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Past research has linked low socio-economic status (SES) to inflammation, metabolic dysregulation, and various chronic and age-related diseases such as type 2 diabetes, coronary heart disease, stroke, and dementia.	26765221
Inflammation, Osage language, Cardiovascular Diseases, Hypoxia, Sleep Apnea, Obstructive	Altered Intercellular Communication	Obstructive sleep apnea (OSA), characterized by repetitive episodes of apnea/hypopnea and hypoxia, is associated with systemic inflammation and induces metabolic, endocrine, and cardiovascular diseases.	26765405
Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	Inflammation might have an impact on neurodegenerative diseases.	26765405
Inflammation, Primary malignant neoplasm, Neoplasms, Hypercalcemia, CTCAE, Weight decreased	Altered Intercellular Communication	Serum PTHrP Predicts Weight Loss in Cancer Patients Independent of Hypercalcemia, Inflammation, and Tumor Burden.	26765580
Inflammation, Hypercalcemia, CTCAE, Neoplasms	Altered Intercellular Communication	Serum PTHrP levels predicted cancer-associated WL independent of the presence of hypercalcemia, inflammation, tumor burden, and other comorbidities.	26765580
Arteritis	Altered Intercellular Communication	Brain large artery inflammation associated with HIV and large artery remodeling.	26765935
Inflammation	Altered Intercellular Communication	To test the hypothesis that brain arteries from HIV+ cases have a greater degree of inflammation than brain arteries from HIV- cases, and that inflammation is associated with brain arterial remodeling.	26765935
Inflammation, herpesvirus 3, human	Altered Intercellular Communication	Arteries from HIV+ cases had a higher inflammation score (B = 0.36, P = 0.05) compared with arteries from HIV- cases, although the association was attenuated after controlling for demographic variables, vascular risk factors, and latent VZV (B = 0.20, P = 0.18).	26765935
Inflammation	Altered Intercellular Communication	Although intimal inflammation was similar in cases with and without HIV, adventitial inflammation was associated with HIV.	26765935
Inflammation, Intracranial Atherosclerosis	Altered Intercellular Communication	Intimal inflammation was associated with intracranial atherosclerosis independent of HIV status, but adventitial inflammation was associated with HIV-associated dolichoectasia in arteries with a thin media.	26765935
Inflammation, Intracranial Atherosclerosis, Vertebrobasilar Dolichoectasia	Altered Intercellular Communication	Adventitial inflammation is associated with HIV and dolichoectasia independent of intracranial atherosclerosis.	26765935
Inflammation	Altered Intercellular Communication	Ly6C+ monocytes from old (18-22 mo) mice and CD14+CD16+ intermediate/inflammatory monocytes from older adults also contributed to this "age-associated inflammation" as they produced more of the inflammatory cytokines IL6 and TNF in the steady state and when stimulated with bacterial products.	26766566
Inflammation	Altered Intercellular Communication	Thus, with age TNF impairs inflammatory monocyte development, function and promotes premature egress, which contribute to systemic inflammation and is ultimately detrimental to anti-pneumococcal immunity.	26766566
Inflammation, Neoplasms	Altered Intercellular Communication	Tumour budding with and without admixed inflammation: two different sides of the same coin?	26766735
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Marked overall peritumoural inflammation has been associated with favourable outcome and may lead to the presence of isolated cancer cells due to destruction of invading cancer cell islets.	26766735
Inflammation, Colorectal Carcinoma, Neoplasms	Altered Intercellular Communication	We assessed the prognostic significance of tumour budding and peritumoural inflammation in a cohort of 381 patients with CRC applying univariate and multivariate analyses.	26766735
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Scattering of invading cancer cell islets by marked overall peritumoural inflammation seems to have a minor role.	26766735
Inflammation, septic, Cerebral dysfunction	Altered Intercellular Communication	We hypothesized that in non-severe septic patients, blood biomarkers of inflammation, endothelial activation, coagulation, and brain function would be different when compared to patients with and without brain dysfunction.	26768428
Steatohepatitis, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	The Distribution of Liver Steatosis, Fibrosis, Steatohepatitis and Inflammation Activity in Alcoholics According to FibroMax Test.	26768633
Necrotizing granulomatous inflammation, Bone Tuberculosis	Altered Intercellular Communication	The diagnosis was confirmed as tubercular osteomyelitis after the biopsy, which showed chronic granulomatous inflammation, and the culture was positive for Mycobacterium tuberculosis.	26768706
Paresis, Myositis, CTCAE 5.0, Myositis	Altered Intercellular Communication	The inclusion body myositis is an inflammatory myopathy that leads to chronic muscle inflammation associated with muscle weakness.	26768933
Inflammation, Blood Clot, Hypoxia	Altered Intercellular Communication	This might be accounted for by factors such as hypoxia, thrombus formation, increased vasoendothelial growth factor release and inflammation affecting both the visible retinal and the unobserved cerebral microvasculature.	26771382
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Therefore, our data reveal that PTB-DM or LTB-DM is characterized by alterations in the systemic levels of adipocytokines, indicating that altered adipose tissue inflammation underlying Type 2 diabetes potentially contributes to pathogenesis of TB disease.	26771473
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Key genes involved in the immune response are generally not associated with intraprostatic inflammation in men without a prostate cancer diagnosis: Results from the prostate cancer prevention trial.	26771888
Inflammation, Prostate carcinoma	Altered Intercellular Communication	We previously reported that both intraprostatic inflammation and SNPs in genes involved in the immune response are associated with prostate cancer risk and disease grade.	26771888
Inflammation	Altered Intercellular Communication	After creating a genetic risk score from the three SNPs possibly associated with inflammation, the odds of inflammation increased with increasing number of risk alleles (P-trend = 0.008).	26771888
Inflammation, Prostate carcinoma	Altered Intercellular Communication	While our findings do not generally support a cross-sectional link between individual SNPs in key genes involved in the immune response and intraprostatic inflammation in men without a prostate cancer diagnosis, they do suggest that some of these variants when in combination may be associated with intraprostatic inflammation in benign tissue.	26771888
Inflammation, atherosclerotic	Altered Intercellular Communication	Inflammation is involved in all stages of development of atherosclerotic plaques.	26771969
Interstitial inflammation	Altered Intercellular Communication	Despite lack of active urinary tract infection, interstitial inflammation was more prevalent in struvite SFs compared to CaOx SFs (43.5% vs 7.3%, P = .0001).	26772639
Inflammation, Dental Plaque	Altered Intercellular Communication	Struvite SFs have less plaque formation than CaOx SFs, but demonstrate evidence of severe parenchymal inflammation compared to other SFs.	26772639
Interstitial inflammation	Altered Intercellular Communication	The role of this prominent interstitial inflammation requires further study.	26772639
Inflammation	Altered Intercellular Communication	The constitutive inflammation that characterizes advanced age is termed inflamm-aging.	26772806
Inflammation	Altered Intercellular Communication	The constitutive inflammation that characterizes advanced age is termed inflamm-aging.	26772806
Inflammation	Altered Intercellular Communication	Testosterone associated inversely with weight, the degree of inflammation (i.e.	26772984
Sepsis, Inflammation	Altered Intercellular Communication	The results of our study provide indirect hint that control of inflammation is a major therapeutic approach in sepsis, and may facilitate to ameliorate the progressive cardiovascular collapse.	26772992
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	These results suggested that adzuki beans attenuate lipid accumulation and oxidative stress-induced inflammation by suppressing hepatic messenger RNA expression of lipogenic and inflammatory mediators in NAFLD.	26773785
Pneumonitis	Altered Intercellular Communication	Previously, in an experimental animal model, we found that simvastatin (Sv) pretreatment was effective in preventing ROFA induced lung inflammation.	26773838
Vasculitis, Dental Leakage	Altered Intercellular Communication	Microvascular inflammation in 5xFAD mice presented with sporadic FITC-albumin leakages at M4 becoming more prevalent at M9 and M12.	26774030
Cerebral Amyloid Angiopathy, Vasculitis, Dental Plaque	Altered Intercellular Communication	Cerebral amyloid angiopathy and microvascular inflammation occur in 5xFAD mice concomitantly to parenchymal plaque deposition.	26774030
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Peptic ulceration connected with chronic inflammation in gastrointestinal mucosa could be induced by Helicobacter pylori infection.	26774268
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor alpha (TNF-a) encoded by TNFA gene is a key mediator in the inflammation process.	26774268
Airway structure, Asthma	Altered Intercellular Communication	Bronchial asthma is characterised by airway inflammation and remodelling with a decline of lung function.	26774356
Inflammation, Obesity	Altered Intercellular Communication	Obesity is characterised by chronic, low-grade systemic inflammation.	26774499
Airway structure, Asthma, Lung diseases	Altered Intercellular Communication	Elevated FeNO levels reflect airway inflammation in various lung diseases including asthma.	26774499
Endocrine System Diseases, Traumatic injury, Hereditary	Altered Intercellular Communication	The exact etiology remains unclear, but trauma, hormonal disturbances, pregnancy, genetic and hereditary factors are postulated to be in association with its' development.	26774632
Inflammation, Malnutrition	Altered Intercellular Communication	Serum pregnancy-associated plasma protein A correlates with inflammation and malnutrition in patients treated with maintenance hemodialysis.	26774806
Bone Diseases, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	Advanced chronic kidney disease (CKD) leads to complications such as anemia, electrolyte abnormalities, bone and mineral disorder, and malnutrition-inflammation-atherosclerosis (MIA) syndrome, that result in high cardiovascu- lar mortality.	26774806
Inflammation	Altered Intercellular Communication	One of the biomarkers associated with inflammation and cardiovascular events is pregnancy-associated plasma protein A (PAPP-A).	26774806
Inflammation, Malnutrition	Altered Intercellular Communication	It positively correlated with N-terminal pro-brain natriuretic peptide (NT-proBNP), serum sodium, and the markers of inflammation and malnutrition.	26774806
Seizures, Acute inflammation, Rasmussen Syndrome	Altered Intercellular Communication	Absence of seizures in Rasmussen encephalitis with active inflammation.	26775150
Seizures, Inflammation, Neurologic Deficits, Epilepsy	Altered Intercellular Communication	Our patient's quite remarkable neurologic deficits along with active inflammation in the absence of epilepsy supports that, at least in some individuals, unilateral hemispheric progressive inflammation can occur without active seizure activity.	26775150
TNM Staging System, Rupture	Altered Intercellular Communication	Receipt of mitotane was associated with hormonal secretion (58% vs 32%; p = 0.001), advanced TNM stage (stage IV: 42% vs 23%; p = 0.021), adjuvant chemotherapy (37% vs 5%; p < 0.001), and adjuvant radiation (17% vs 5%; p = 0.01), but was not associated with tumor rupture, margin status, or N-stage.	26775162
Vascular Diseases, Inflammation	Altered Intercellular Communication	Furthermore, we tested whether (1) cognitive slowing and (risk factors for) vascular diseases, (2) a marker of chronic inflammation, and (3) specific somatic conditions could explain this association.	26775581
Inflammation, Degenerative polyarthritis, Chronic Obstructive Airway Disease, Chronic disease, Comorbidity	Altered Intercellular Communication	Specific somatic comorbidity (number of chronic diseases, chronic obstructive pulmonary disease, osteoarthritis) or inflammation influenced the odds ratio.	26775581
Inflammation, Asthma	Altered Intercellular Communication	Eosinophilic inflammation is frequently associated with increased asthma severity.	26775606
Inflammation	Altered Intercellular Communication	Association of synovial inflammation and inflammatory mediators with glenohumeral rotator cuff pathology.	26775747
Inflammation	Altered Intercellular Communication	We hypothesized that patients with full-thickness rotator cuff tears would have greater synovial inflammation compared with those without rotator cuff tear pathology, with gene expression relating to histologic findings.	26775747
Tears body substance, Inflammation	Altered Intercellular Communication	Patients with full-thickness rotator cuff tears have greater levels of synovial inflammation, angiogenesis, and MMP-3 upregulation compared with controls.	26775747
Iron deficiency anemia, Inflammation, Anemia, idarubicin	Altered Intercellular Communication	Of the 2401 participants, 18.9% had anaemia, 1.9% had anaemia related to inflammation (AI), and 1.3% had iron-deficiency anaemia (IDA).	26775754
Necrotizing granulomatous inflammation, Inflammation, Abscess, Pseudoepitheliomatous hyperplasia	Altered Intercellular Communication	The most common histopathological findings were chronic granulomatous inflammation, suppurative inflammation, sinus and abscess formation, pseudoepitheliomatous hyperplasia, transepidermal elimination and scarring.	26776602
Arterial Stiffness, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Low-Grade Inflammation and Increased Arterial Stiffness in Chinese Youth and Adolescents with Newly-Diagnosed Type 2 Diabetes Mellitus.	26777037
Arterial Stiffness, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	To investigate the relationship between low-grade inflammation (LI) and increased arterial stiffness in Chinese youth and adolescents with newly-diagnosed type 2 diabetes mellitus (T2DM).	26777037
Inflammation	Altered Intercellular Communication	Ninety-eight subjects aged 10 to 24 years with newly-diagnosed T2DM were investigated for findings of general inflammation.	26777037
Hypersensitivity	Altered Intercellular Communication	These findings suggest that Resveratrol as a therapeutic agent could inhibit PGD2-mediated inflammation but would be ineffective against histamine-mediated allergic reactions.	26777630
allergic inflammation	Altered Intercellular Communication	However, Resveratrol could potentially exacerbate or promote allergic inflammation by enhancing IgE-dependent TNF production from mast cells in human skin.	26777630
Inflammation, Pulmonary Hypertension	Altered Intercellular Communication	Serum levels of interleukin-18-binding protein isoform a: Clinical association with inflammation and pulmonary hypertension in systemic sclerosis.	26777734
Inflammation, Sample Size Calculation, Pulmonary Hypertension	Altered Intercellular Communication	These results suggest that the inhibition of IL-18 signaling by IL-18BPa may be involved in the development of pulmonary vascular involvement leading to pulmonary hypertension and modulate the systemic inflammation in SSc.	26777734
Communicable Diseases, Inflammation, Neoplasms, Paralysed	Altered Intercellular Communication	Acute flaccid paralysis is associated with inflammation, infection, or tumors in the spinal cord or peripheral nerves.	26778096
Inflammation, Nonarteritic anterior ischemic optic neuropathy (NAION), Thrombophilia, Atherosclerosis	Altered Intercellular Communication	Associations between thrombophilic risk factors and determinants of atherosclerosis and inflammation in patients with non-arteritic anterior ischaemic optic neuropathy.	26778257
Inflammation, Thrombophilia, Atherosclerosis	Altered Intercellular Communication	We analyzed thrombophilic risk factors and determinants of atherosclerosis and inflammation in 109 consecutive patients and 109 age- and sex-matched volunteers using a case-control design.	26778257
Inflammation	Altered Intercellular Communication	Inflammation influences cognitive development in infants and older adults, however, how inflammation may affect academic development during childhood and adolescence remains to be elucidated.	26778777
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Latest data suggests that inflammation plays a critical role in the pathogenesis of OA.	26780447
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Blood neutrophil-lymphocyte ratio (NLR) is a simple non-invasive and cost-effective marker of inflammation in various systemic diseases, but it has not been investigated in OA yet.	26780447
Refractory anemias, Inflammation, Osteoporosis	Altered Intercellular Communication	We herein assessed serum FGF23 and its relationship to inflammation and osteoporosis in patients with RA.	26781009
Refractory anemias, Inflammation	Altered Intercellular Communication	Conclusion In patients with RA, serum FGF23 is correlated with inflammation, the disease activity of RA, and bone absorption markers.	26781009
Inflammation	Altered Intercellular Communication	Serum FGF23 may be associated with abnormal bone absorption related to RA inflammation.	26781009
Inflammation, Necrosis, Fibrosis Assessment, Mesenteric Panniculitis, Hyperplastic Polyp	Altered Intercellular Communication	Mesenteric panniculitis (MP) is a benign fibroinflammatory process characterized by the presence of fat necrosis, chronic inflammation and fibrosis in the mesentery.	26781011
Malignant Neoplasms	Altered Intercellular Communication	Although various causal factors, such as malignancy, chronic inflammatory conditions and autoimmune processes, have been identified, the precise etiology remains unknown.	26781011
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow limitation and inflammation.	26781464
Diabetes Mellitus, Atherosclerosis	Altered Intercellular Communication	Parathyroid hormone is associated with incident diabetes in white, but not black adults: The Atherosclerosis Risk in Communities (ARIC) Study.	26782010
Refractory anemias, Rheumatoid Arthritis, destruction joint, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is characterized by chronic synovial inflammation and subsequent joint destruction.	26782362
Prostate carcinoma, prostatitis	Altered Intercellular Communication	Greater extent of prostate inflammation in negative biopsies is associated with lower risk of prostate cancer on repeat biopsy: results from the REDUCE study.	26782712
Prostate carcinoma, prostatitis, Structure of posterior cerebral artery	Altered Intercellular Communication	To evaluate whether the extent of baseline acute prostate inflammation (API) and chronic prostate inflammation (CPI) was associated with risk of prostate cancer (PCa) at 2-year repeat prostate biopsy in a clinical trial with systematic biopsies independent of PSA.	26782712
Inflammation, Chronic heart failure	Altered Intercellular Communication	Nutritional Status is Associated with Inflammation and Predicts a Poor Outcome in Patients with Chronic Heart Failure.	26782970
Inflammation, Atherosclerosis, Congestive heart failure	Altered Intercellular Communication	These data indicate that a poor nutritional status as assessed using the CONUT score and atherosclerosis as indicated by CIMT is significantly associated with inflammation and predicts poor outcomes in patients with CHF.	26782970
Inflammation, Colitis	Altered Intercellular Communication	Most colonoscopies showed ulcerations involving the rectum and sigmoid, 66% of patients had extensive colitis, 55% had patchy distribution and 20% had ileal inflammation.	26783344
Inflammation, FAM126A gene	Altered Intercellular Communication	Serum IL-10 and IL-12 were elevated significantly with disease progression (P < 0.0001) and a positive correlation coefficient was detected between IL-10, IL-12 (r = 0.785, P < 0.0001), and transaminase values suggesting their possible role in chronic inflammation progression leading to HCC.	26783377
Inflammation, FAM126A gene	Altered Intercellular Communication	IL-10 and IL-12 might be involved in chronic inflammation progression leading to HCC and their evaluation could be used as new biomarkers to reflect the degree of inflammation in HCC development.	26783377
Psoriasis	Altered Intercellular Communication	Consistently, in human psoriasis and in a mouse model of a psoriasis-like skin inflammation, epidermal vaspin expression was significantly down-regulated.	26783881
Psoriasis	Altered Intercellular Communication	Down-regulation of vaspin in KCs resulted in decreased expression of differentiation-associated genes and up-regulation of interferon-inducible and inflammation-associated psoriasis signature genes.	26783881
Myeloid Progenitor Cells	Altered Intercellular Communication	Consequently, the application of vaspin inhibited myeloid cell infiltration in a mouse model of a psoriasis-like skin inflammation.	26783881
Tissue damage, Inflammation	Altered Intercellular Communication	MIF reflects tissue damage rather than inflammation in post-cardiac arrest syndrome in a real life cohort.	26784134
Orbital Pseudotumor	Altered Intercellular Communication	The authors describe a case of a 61-year-old woman, initially diagnosed with idiopathic orbital inflammation refractory to multiple immunosuppressive agents.	26784550
Corneal epithelial defect, Inflammation, Xerophthalmia	Altered Intercellular Communication	He exhibited bilateral conjunctival xerosis with complete corneal melt in the right eye and a large corneal epithelial defect with underlying anterior chamber inflammation in the left eye.	26785304
Inflammation, Hypoxia	Altered Intercellular Communication	Furthermore, they delineate the relationship of measurable tissue hypoxia within the STK and markers of inflammation in human ARAS.	26787779
Inflammation, Hypertrophy	Altered Intercellular Communication	Increased expression of receptor for advanced glycation end products (RAGE) in adipose tissue has been associated with inflammation, adipocyte hypertrophy, and impaired insulin signal.	26788516
Airway structure, Allergic asthma, Exacerbation, Symptoms	Altered Intercellular Communication	Omalizumab, an anti-immunoglobulin E (IgE) monoclonal antibody, inhibits the binding of circulating IgE to mast cells and basophils, resulting in fewer episodes of airway inflammation, asthma symptoms and exacerbations in patients with severe allergic asthma.	26790100
Diabetes with coma (disorder), Inflammation	Altered Intercellular Communication	Laboratory data suggested acute inflammation and hyperosmolar hyperglycemic syndrome.	26790763
Inflammation	Altered Intercellular Communication	The patient was finally discharged after complete recovery from severe inflammation.	26790763
Inflammation, Hemoptysis	Altered Intercellular Communication	After 48 h, the patient became unwell with frank haemoptysis and features of systemic inflammation.	26791127
Diabetic Retinopathy, Inflammation	Altered Intercellular Communication	"Association between platelet activating factor acetylhydrolase and diabetic retinopathy: Does inflammation affect the retinal status?".	26791393
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Galectin-1 Couples Glycobiology to Inflammation in Osteoarthritis through the Activation of an NF-kB-Regulated Gene Network.	26792806
Degenerative polyarthritis, Inflammation, Degenerative disorder of cartilage	Altered Intercellular Communication	Because inflammation is critical to cartilage degeneration in osteoarthritis, this report reveals an intimate relation of glycobiology to osteoarthritic cartilage degeneration.	26792806
Granulomatous inflammation, Focal necrosis, Vasculitis, CTCAE	Altered Intercellular Communication	A right nasal biopsy was performed which revealed granulomatous inflammation with focal necrosis and vasculitis.	26793412
Encephalitis, Inflammation	Altered Intercellular Communication	Encephalitis is a brain inflammation, which could involve also the meninges.	26793848
Lipogranuloma	Altered Intercellular Communication	Adult-onset xanthogranuloma (AOX) of the corneoscleral limbus is a rare inflammatory condition of unknown aetiology.	26794218
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	In conclusion, higher mtDNA copy number associated with lower incidence of CKD independent of traditional risk factors and inflammation biomarker levels in this cohort.	26794963
Inflammation	Altered Intercellular Communication	As GDF-15 is a marker of chronic inflammation and oxidative stress, our finding of increased serum GDF-15 in patients with NP supports the hypothesis that its pathogenesis involves chronic inflammation and oxidative stress.	26795264
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	We sought to evaluate the relationship between (18)F-FDG uptake in supraclavicular BAT in relation to arterial inflammation and subsequent cardiovascular disease (CVD) events in humans.	26795284
Arteritis	Altered Intercellular Communication	BAT activity negatively correlated with arterial inflammation (r = -0.178, P < 0.01), a relationship that persisted after correcting for age and BMI (r = -0.147, P < 0.01).	26795284
Arteritis	Altered Intercellular Communication	Our results suggest that increased supraclavicular BAT activity is inversely associated with arterial inflammation, independently of age and BMI.	26795284
Communicable Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The most common large-bowel pathologies included malignancy (51%), inflammation (15%), and infection (15%).	26795889
Communicable Diseases, Inflammation	Altered Intercellular Communication	This might be that the antimicrobial PHMB component of the novel dressing played a role to reduce infection and inflammation reaction.	26796543
Vascular Diseases, Malignant Neoplasms	Altered Intercellular Communication	Specific note was made of cases with active malignancy, vascular disorders, or inflammatory conditions with an increased risk of vasculopathy.	26797023
Granulomatous inflammation	Altered Intercellular Communication	Histologically, numerous eggs of F. hepatica were noted with acute and chronic granulomatous inflammations in the subserosa and pericolic adipose tissues.	26797440
Inflammation, Diabetes, Autoimmune	Altered Intercellular Communication	Administration with SGAD65190-315 /IL-10 blocked the onset of autoimmune diabetes in NOD mice, significantly suppressed islet inflammation, inhibited the apoptosis of islet b cells, induced immune tolerance to autoantigen GAD65 and proinsulin and shifted the Th1/Th2 balance towards Th2.	26797873
Inflammation, Toxic effect	Altered Intercellular Communication	At 30 mg, a dose-limiting toxicity (grade III mucosal inflammation) was observed.	26798966
Inflammation, Neoplasms	Altered Intercellular Communication	Under different inflammation states, proinflammatory cytokine intensity, in addition to tumor stage, independently predicted PFSR in patients with CRP <5 mg/L, whereas tumor stage was the only independent predictor of PFSR in patients with CRP >=5 mg/L.	26799163
Inflammation, Polypoidal choroidal vasculopathy, Humor	Altered Intercellular Communication	The Features of Inflammation Factors Concentrations in Aqueous Humor of Polypoidal Choroidal Vasculopathy.	26799405
Inflammation, Necrosis	Altered Intercellular Communication	A necrotic background with paucity of inflammation was frequently seen in lung FNA.	26800146
Inflammation, Arthritis, Periodontitis	Altered Intercellular Communication	We examined the efficacy of ProCT and hsCRP as biomarkers of periodontitis in the saliva and serum of patients with arthritis, which is characterized by variable levels of systemic inflammation that potentially can confound the interpretation of inflammatory biomarkers.	26800284
Refractory anemias, Inflammation, Periodontitis, Degenerative polyarthritis	Altered Intercellular Communication	Any elevation in salivary and serum hsCRP due to periodontitis apparently was overshadowed by differences among these patients in factors that influence CRP, such as the extent of inflammation between RA and OA, the extent of adipose tissue, the use of anti- inflammatory medications and smoking status.	26800284
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Because no inflammation was present upon examination, we observed the patient without prescribing any additional medications except for the eye drop treatment for glaucoma.	26800888
Hepatobiliary Disorder	Altered Intercellular Communication	The liver disease (D) variable did not account for four patients with inflammation/cirrhosis.	26801328
Crohn Disease	Altered Intercellular Communication	MicroRNA-124 Promotes Intestinal Inflammation by Targeting Aryl Hydrocarbon Receptor in Crohn's Disease.	26802080
Gastrointestinal inflammation	Altered Intercellular Communication	These findings suggest that miR-124 induces intestinal inflammation by inhibiting AHR to modulate pro-inflammatory cytokine production and thereby promotes the pathogenesis of CD.	26802080
Inflammation, MS gene	Altered Intercellular Communication	Differences between adult white and grey matter miRNA expression included higher expression of pro-inflammatory miRNAs in the former, potentially contributing to differences in inflammation between grey and white matter plaques in multiple sclerosis.	26802178
Inflammation, Dyslipidemias, Atherosclerosis	Altered Intercellular Communication	Dyslipidemia and low-grade inflammation are integral in the pathogenesis of atherosclerosis.	26803431
Chronic laryngitis, Inflammation, Amyloidosis	Altered Intercellular Communication	Chronic subglottic laryngitis with inflammation or another condition such as amyloidosis was initially suspected.	26803452
Hemorrhage, Neoplasms, Epistaxis, Acute hemorrhage, Malignant Neoplasms	Altered Intercellular Communication	Altogether 27/52 patients were treated for malignant tumors, 25/52 were attributable to acute haemorrhage due to epistaxis, after tonsillectomy, benign tumors and bleeding attributable to inflammations.	26803587
Inflammation, Sleep Apnea, Obstructive, Obesity, Osage language	Altered Intercellular Communication	The effect of obesity and medication on the relationship between obstructive sleep apnoea (OSA) and lipidaemia and systemic inflammation is not fully understood for various reasons.	26804247
airway disease, Inflammation	Altered Intercellular Communication	Neutrophil extracellular traps are associated with inflammation in chronic airway disease.	26804470
Inflammation, Neoplasms, Gallbladder Carcinoma	Altered Intercellular Communication	The tumor was initially considered to be unresectable locally advanced gallbladder carcinoma with inflammation, and she received 6 courses of chemotherapy with gemcitabine plus cisplatin.	26805152
Inflammation, Secondary malignant neoplasm of liver, Neoplasms	Altered Intercellular Communication	Subsequently, the inflammation was extinguished, and CT showed the main tumor shrunk and the Glisson's sheath infiltration disappeared; however, a liver metastasis existed in segment 5.	26805152
Inflammation, Carcinoma	Altered Intercellular Communication	There was carcinoma in situ in the main pancreatic duct surrounding chronic inflammation.	26805362
Inflammation, Angiolymphoid hyperplasia	Altered Intercellular Communication	Multicentric Castleman disease (MCD) describes a heterogeneous group of disorders involving systemic inflammation, characteristic lymph node histopathology, and multi-organ dysfunction because of pathologic hypercytokinemia.	26805758
Inflammation, Thrombophilia, Atherosclerosis	Altered Intercellular Communication	We evaluated relationships between DefS, sub-clinical atherosclerosis, low-grade inflammation and hypercoagulation in a bi-ethnic sex cohort.	26806201
Inflammation, Dental Plaque	Altered Intercellular Communication	Ambulatory BP, vascular structure (left carotid cross-sectional wall area (L-CSWA) and plaque counts), and markers of coagulation and inflammation were quantified.	26806201
Inflammation, Hypertensive (finding), Dental Plaque, Thrombophilia	Altered Intercellular Communication	A hypertensive state, less plaque, low-grade inflammation, and hypercoagulation were more prevalent in DefS Africans (27-84%) than DefS Caucasians (18-41%).	26806201
Inflammation, Hyperkinetic, Thrombophilia	Altered Intercellular Communication	Novel findings revealed hypercoagulation, low-grade inflammation and hyperkinetic BP (physiological loss-of-control responses) in DefS African men.	26806201
Crohns disease of the ileum", Colitis	Altered Intercellular Communication	We report three cases of patients with isolated Crohn's ileitis associated with PSC and in whom colonic inflammation was never documented.	26806276
Inflammatory Bowel Diseases, Ileitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Our three cases of PSC with isolated CD ileitis and long-term follow-up without any sign of colonic involvement argue against the concept that colonic mucosal inflammation is critical for the pathogenesis of PSC in inflammatory bowel disease.	26806276
Communicable Diseases, Orgasm induced epilepsy	Altered Intercellular Communication	We describe seizure-induced inflammation-like responses and discuss how these changes may be distinguished from those associated with infection.	26806580
Seizures, Communicable Diseases	Altered Intercellular Communication	We investigated the occurrence of inflammation-like responses, characteristics of the seizures, neurological status at the initial visit, outcomes, and clinical findings to determine the presence of infection.	26806580
Communicable Diseases	Altered Intercellular Communication	An inflammation-like response was observed in 56.3% of all visits and 19.3% were diagnosed with concurrent infection.	26806580
Communicable Diseases	Altered Intercellular Communication	Among the visits with inflammation-like response, 34.7% were shown to have an infection.	26806580
Inflammation, Fibrosis Assessment, Chronic Kidney Diseases, Pathology	Altered Intercellular Communication	Renal fibrosis is a common pathological consequence of chronic kidney disease (CKD) with tissue fibrosis closely associated with chronic inflammation in numerous pathologies.	26806834
Inflammation, Fibrosis Assessment, Chronic Kidney Diseases	Altered Intercellular Communication	Here, we determine whether there is a molecular link between chronic inflammation and tissue fibrosis in CKD progression.	26806834
Inflammation, Fibrosis Assessment, Chronic Kidney Diseases	Altered Intercellular Communication	Our study provides insight into molecular mechanisms underlying chronic inflammation and tissue fibrosis and identifies potential therapeutic targets for CKD treatment.	26806834
Granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	Microbial genes encoding enzymes that can be targeted by currently available antimycobacterial antibiotics are present in sarcoidosis specimens and localize to sites of granulomatous inflammation.	26807608
cervical cancer	Altered Intercellular Communication	Adherence to current cervical cancer screening guidelines should minimize the increased risk of CC associated with these hormonal risk factors.	26808155
Inflammation, Levator palpebrae superioris structure	Altered Intercellular Communication	Levator palpebrae superioris enlargement from inflammation or scar is a factor in thyroid eye disease-related ULR.	26808176
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	In addition, specimens demonstrated varying degrees of fibrosis (8 cases, 66.7%), necrosis (6 cases, 50%), spongiosis (5 cases, 41.7%), and perifollicular inflammation (6 cases, 50%).	26808178
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The MFB has been indicated as a culprit in chronic inflammation and fibrosis.	26808567
Inflammation	Altered Intercellular Communication	The reduction of HDAC2 expression not only directly enhances the expression of inflammatory genes, but may account for the activation of NF-kB mediated inflammation.	26809128
Inflammation, Malnutrition, Hematological Disease	Altered Intercellular Communication	Erythrocyte morphology changes not only by primary hematological diseases but also by systemic inflammation, ineffective erythropoiesis and nutritional deficiencies.	26809230
Inflammation	Altered Intercellular Communication	PET scans indicated increased standardized uptake values, and 7/8 patients were correctly diagnosed with benign inflammation.	26809651
Vaginitis, Vaginal Diseases	Altered Intercellular Communication	Bacterial vaginosis, aerobic vaginitis, vaginal inflammation and major Pap smear abnormalities.	26810061
Inflammation, doxorubicin/vincristine protocol, Abnormality of the cervical spine	Altered Intercellular Communication	On the other hand, moderate or severe inflammation (msI) (41.0 % vs. 28.8 %, p = 0,04), moderate or severe AV (msAV) (16.9 % vs. 7.2 %, p = 0.009) and msAV/BV (37.3 % vs. 20.0 %, p = 0.001) were more common in women with such major cervical abnormalities.	26810061
Communicable Diseases, Dystrophic calcification, Inflammation, Traumatic injury	Altered Intercellular Communication	We present a case of dystrophic calcification occurring entirely within the parotid gland in a 7-year-old girl without apparent inciting inflammation, infection, or trauma.	26810287
Inflammation, Keratosis	Altered Intercellular Communication	Topical corticosteroid has no influence on inflammation or efficacy after ingenol mebutate treatment of grade I to III actinic keratoses (AK): A randomized clinical trial.	26810403
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Inflammation and oxidative stress play important roles in the pathogenesis of obstructive sleep apnoea syndrome (OSAS).	26810494
Inflammation	Altered Intercellular Communication	We investigate if Ado system, that plays an important role in central nervous system, in vascular system, and also in inflammation, is involved in pathophysiology of iNPH disease.	26810542
Inflammation, Pineal germinoma, Demyelinating Diseases	Altered Intercellular Communication	In this report, we describe the case of a 13-year-old boy with a bilateral thalamic germinoma which initially mimicked tumefactive demyelinating disease with inflammation, based on the clinical symptoms, imaging results and histology of a biopsy specimen obtained endoscopically.	26811911
Inflammation, Opportunistic Infections	Altered Intercellular Communication	These changes may impact clinical outcomes of HF with respect to inflammation, opportunistic infections and physical recovery.	26812523
Inflammation, Chlamydia trachomatis, Corneal pannus	Altered Intercellular Communication	Can corneal pannus with trachomatous inflammation--follicular be used in combination as an improved specific clinical sign for current ocular Chlamydia trachomatis infection?	26812948
Trachoma , Perifolliculitis	Altered Intercellular Communication	Mass drug administration (MDA) for trachoma control is administered based on the population prevalence of the clinical sign of trachomatis inflammation - follicular (TF).	26812948
Ulcerative Colitis, Colitis	Altered Intercellular Communication	IL-36a expression is elevated in ulcerative colitis and promotes colonic inflammation.	26813344
Inflammatory Bowel Diseases, Psoriasis, Gastrointestinal inflammation	Altered Intercellular Communication	Although significant mechanistic overlap can exist between psoriasis and inflammatory bowel disease (IBD), to date there have been no reports investigating the IL-36 family in gastrointestinal inflammation.	26813344
Inflammatory disease of mucous membrane	Altered Intercellular Communication	This elevated expression is mirrored in the inflamed colonic mucosa of mice, wherein IL-36 receptor deficiency confirmed this pathway as a mediator of mucosal inflammation.	26813344
Inflammatory Bowel Diseases, Colitis	Altered Intercellular Communication	These data identify a novel role for IL-36 signaling in colonic inflammation and indicate that the IL-36R pathway may represent a novel target for therapeutic intervention in IBD.	26813344
Inflammation, Adenocarcinoma, Clear Cell, Neoplasms	Altered Intercellular Communication	We reviewed 109 unselected ovarian clear cell carcinomas for specific tumor characteristics (architecture, nuclear atypia, signet ring cells, stromal hyalinization, background precursor) and inflammatory response (peritumoral lymphocytes found along the leading edge of the tumor, intratumoral stromal inflammation found within the tumor, percentage of plasma cells in the intratumoral stromal inflammation, tumor-infiltrating lymphocytes) and performed immunohistochemistry for all 4 MMR proteins.	26813747
Chronic lymphocytic inflammation, Pontine structure, Clippers, Inflammatory disorder	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a recently described inflammatory disease of the central nervous system, distinguished by brainstem- and spinal cord-centered lesions with a characteristic contrast enhancement on MRI, a lymphocytic perivascular infiltrate on pathological exam, and a dramatic response to and dependence on steroids therapy.	26813773
ARCN1 gene, Upper Respiratory Infections	Altered Intercellular Communication	Exhaled and non-exhaled non-invasive markers for assessment of respiratory inflammation in patients with stable COPD and healthy smokers.	26814886
ARCN1 gene, Chronic Obstructive Airway Disease, Upper Respiratory Infections	Altered Intercellular Communication	We aimed at comparing exhaled and non-exhaled non-invasive markers of respiratory inflammation in patients with chronic obstructive pulmonary disease (COPD) and healthy subjects and define their relationships with smoking habit.	26814886
ARCN1 gene, Upper Respiratory Infections	Altered Intercellular Communication	An approach combining different types of outcomes can be used for assessing respiratory inflammation in patients with COPD.	26814886
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	We sought to characterize the relationship between fat radiodensity and quantity in subcutaneous, visceral, and intermuscular fat depots, and its role in inflammation, insulin resistance, and metabolic syndrome (MetS).	26817938
Inflammation, Ischemia	Altered Intercellular Communication	Similar electrophysiological findings were observed in our study and we propose that this may be due to oxidative stress, and inflammation that occurs secondary to chronic ischemia.	26818163
Inflammation	Altered Intercellular Communication	Specific members of the RING finger [RNF] protein family serve as E3 ubiquitin ligases and play important roles in the regulation of inflammation.	26818663
Gastrointestinal inflammation	Altered Intercellular Communication	RNF183 promoted intestinal inflammation via the activation of the NF-kB pathway by increasing the ubiquitination and degradation of IkBa.	26818663
Gastrointestinal inflammation	Altered Intercellular Communication	RNF183, which is negatively regulated by miR-7, is a novel regulator promoting intestinal inflammation by increasing the ubiquitination and degradation of IkBa, thereby inducing NF-kB activation.	26818663
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Co-morbidity in patients with early rheumatoid arthritis - inflammation matters.	26818851
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation is important for the development of cardiovascular disease, but little is known on its relationship with other co-morbidities.	26818851
Refractory anemias, Inflammation	Altered Intercellular Communication	We investigated the role of inflammation for the development of new comorbidities in early RA.	26818851
Communicable Diseases, Primary malignant neoplasm, "Richters syndrome	Altered Intercellular Communication	After comprehensive evaluation, the etiology of neurological symptoms was: central nervous system chronic lymphocytic leukemia in 18 patients (10% evaluated by imaging and/or lumbar puncture, 0.4% overall cohort); central nervous system Richter Syndrome in 15 (9% evaluated, 0.3% overall); infection in 40 (23% evaluated, 1% overall); autoimmune/inflammatory conditions in 28 (16% evaluated, 0.7% overall); other cancer in 8 (5% evaluated, 0.2% overall); and another etiology in 63 (37% evaluated, 1.5% overall).	26819053
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Mesenchymal stromal cells (MSCs) may reduce inflammation and promote tissue repair in pulmonary emphysema.	26819296
Inflammation, Damage	Altered Intercellular Communication	Early recognition is important as ongoing fibrosing inflammation may result in organ damage.	26819361
Bronchiectasis	Altered Intercellular Communication	Neutrophilic Bronchial Inflammation Correlates with Clinical and Functional Findings in Patients with Noncystic Fibrosis Bronchiectasis.	26819500
Bronchiectasis, Bronchitis	Altered Intercellular Communication	Neutrophilic bronchial inflammation is a main feature of bronchiectasis, but not much is known about its relationship with other disease features.	26819500
Inflammation, Colonization	Altered Intercellular Communication	Sputum neutrophilic inflammation and biomarkers of oxidative stress in EBC can be considered good biomarkers of disease severity in NCFB patients, as confirmed by pulmonary function, disease duration, bacterial colonization, BSI score, and exacerbation rate.	26819500
Anxiety, CTCAE 3.0, Perimenopausal state	Altered Intercellular Communication	Anxiety sensitivity (dimension of psychological concerns) might be an important vulnerability factor in the experience of perimenopausal distress among women closer to menopause, whereas the predisposition to an anxiety response might contribute to perimenopausal distress near the beginning of reproductive hormonal changes.	26821968
Inflammation, Cardiovascular Diseases, Diabetes Mellitus	Altered Intercellular Communication	Ingenuity pathway analysis and gene set enrichment analysis revealed that inflammation, cardiovascular disease and diabetes signal transduction pathways and amyloid b metabolism were major components of the neuronal response to glutamate excitotoxicity.	26822027
Diabetic peripheral neuropathy, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	A high thyroid stimulating hormone level is associated with diabetic peripheral neuropathy in type 2 diabetes patients.	26822260
Inflammation, Carcinoma	Altered Intercellular Communication	Histology of the resection specimen confirmed active inflammation in the colon and rectum and a carcinoma in situ was identified in the sigmoid colon without invasive growth.	26822612
Inflammation, MS gene, Cerebral atrophy	Altered Intercellular Communication	Laquinimod had beneficial effects on inflammation, brain atrophy and disease progression in multiple sclerosis (MS) in two phase III clinical trials.	26823290
Inflammation, Primary malignant neoplasm, Cardiovascular Diseases	Altered Intercellular Communication	Plasma Biomarkers of Inflammation, the Kynurenine Pathway, and Risks of All-Cause, Cancer, and Cardiovascular Disease Mortality: The Hordaland Health Study.	26823439
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	In this general population, plasma biomarkers of inflammation and kynurenines were associated with risk of all-cause, cancer, and CVD mortality.	26823439
Atrial Fibrillation by ECG Finding, Metabolic Syndrome X, Fibrosis Assessment, Rheumatic Heart Disease, Diabetes Mellitus, Obesity, Atrial Fibrillation	Altered Intercellular Communication	Fibroblast growth factor-21 (FGF-21) has been discovered as a strong hormone, plays an important role in lipid metabolism, glucose metabolism, associated with several diseases such as obesity, metabolic syndrome, diabetes mellitus, and cardiovascular events; however, no evidence is available concerning the relationship of FGF-21 and atrial fibrosis in patients with atrial fibrillation (AF) and rheumatic heart disease (RHD).	26823820
Inflammation, Hyperpigmentation	Altered Intercellular Communication	Biopsy showed groups of apoptotic keratinocytes, basal hyperpigmentation, and slight dermal inflammation.	26825158
Inflammation, Urticaria, Sweet Syndrome	Altered Intercellular Communication	These 2 histopathologic patterns of ND, early and late, resemble neutrophilic urticarial dermatitis (also known as neutrophilic dermatitis with systemic inflammation) and Sweet syndrome, respectively.	26825166
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Association between diet-related inflammation, all-cause, all-cancer, and cardiovascular disease mortality, with special focus on prediabetics: findings from NHANES III.	26825592
Inflammation, Primary malignant neoplasm, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus	Altered Intercellular Communication	Chronic inflammation is associated with increased risk of cancer, cardiovascular disease (CVD), and diabetes.	26825592
Inflammation, Diabetic Ketoacidosis, Diabetes Mellitus	Altered Intercellular Communication	Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes mellitus and the novel systemic inflammation marker platelet-to-lymphocyte ratio (PLR) may be associated with clinical outcome in patients with DKA.	26825908
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays an important role in the pathogenesis of atherosclerosis.	26825917
Inflammation	Altered Intercellular Communication	Recent studies suggest that the neutrophil-lymphocyte ratio (NLR) as a marker of inflammation is associated with mortality in surgical patients.	26825931
Ulcerative Colitis	Altered Intercellular Communication	Cigarette smoke suppresses inflammation-induced apoptosis in intestinal epithelial cells (DLD-1), which may explain its protective effect in UC.	26826017
Inflammation, Liver Dysfunction, Heart Diseases, Systemic disease, Malignant Neoplasms	Altered Intercellular Communication	Patients with systemic diseases, including structural heart disease, hepatic or renal dysfunction, collagen disease, malignancy, and inflammation were excluded.	26826137
Inflammation	Altered Intercellular Communication	D-dimer is a manifestation of endogenous fibrinolytic activity and associated with inflammation process.	26826394
ARCN1 gene, Inflammation	Altered Intercellular Communication	D-dimer is increased in COPD patients, and could be considered as an inflammatory marker for the assessment of inflammation in the progression of COPD.	26826394
Inflammation, Liver Cirrhosis, FAM126A gene	Altered Intercellular Communication	HCV is suspected to induce HCC primarily through chronic inflammation and promotion of cirrhosis, a well-known pre-neoplastic condition.	26827631
Inflammation, Impaired cognition, Data types - Address, Nerve Degeneration	Altered Intercellular Communication	CSF YKL-40, a biomarker of glial inflammation, is associated with a cerebral structural signature distinct from that related to p-tau neurodegeneration at the earliest stages of cognitive decline due to AD.	26827642
Inflammation	Altered Intercellular Communication	Histological remission was defined as absence of active inflammation (Geboes score <3.1) and absence of basal plasmacytosis.	26829408
Inflammation, Hemolysis (biological function)	Altered Intercellular Communication	Multivariate logistic regression and receiver operating characteristics (ROC) analysis revealed a significant association between increased risk of breakthrough hemolysis and prolonged dosing intervals of 17 days or more and concomitant inflammation: odds ratios (OR) and 95% confidence intervals (CIs) were 1.6 (1.3-2.0, p<0.01) and 5.5 (1.3-22.8, p=0.02), respectively.	26830487
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Objective Although chronic obstructive pulmonary disease (COPD) is characterized by systemic inflammation, the association between the neutrophil to lymphocyte ratio (NLR; an indicator of inflammation) and the clinical status of COPD has not been well studied.	26831014
ARCN1 gene, Asthma, Airway structure	Altered Intercellular Communication	As patients with COPD and asthma already have a compromised respiratory function and chronic airway inflammation, they are expected to be at increased risk for adverse respiratory health effects.	26831047
Inflammation, Angiolymphoid hyperplasia, Lymphadenopathy	Altered Intercellular Communication	Multicentric Castleman's disease (MCD) is a pre-malignancy that presents with lymphadenopathy and features of systemic inflammation.	26831502
Ischemia, Inflammation	Altered Intercellular Communication	Magnetic resonance imaging showed diffusion restriction concerning for ischemia with areas of ring enhancement suggestive of inflammation.	26831951
fibroma, Inflammation, Granuloma	Altered Intercellular Communication	There was a significant correlation between mast cell count and the intensity of inflammation in the irritation fibroma and pyogenic granuloma groups.	26832178
Inflammation, Damage	Altered Intercellular Communication	Serum 14-3-3e protein is a joint-derived biomarker that up-regulates cytokines and enzymes that perpetuate local and systemic inflammation and may contribute to joint damage.	26832367
Inflammation, Psoriasis, Metabolic Syndrome X, Cardiovascular Abnormalities	Altered Intercellular Communication	The inexorable inflammation in patients of psoriasis predisposes to various disorders, notably, a cluster of cardiovascular and metabolic abnormalities christened 'metabolic syndrome'.	26832843
Granulomatous inflammation	Altered Intercellular Communication	Results showed a 2 mm-long whitish nematode spiralised in muscular layer of colon mucosa surrounded by granulomatous inflammation.	26832924
Dermatitis, Atopic, Inflammation	Altered Intercellular Communication	First-line treatments for atopic eczema focus on maintaining and repairing the skin barrier (emollients) and reducing inflammation (topical steroids); allergen and irritant avoidance are also important to achieve disease control.	26833520
Acute and chronic inflammation	Altered Intercellular Communication	The patients with chronic sinonasal inflammation were treated with fluticasone nasal spray for 14 days.	26833624
Communicable Diseases, Helicobacter pylori, Inflammation	Altered Intercellular Communication	Its development is closely linked to an infection with Helicobacter pylori and chronic, cytokine-driven inflammation.	26835712
Inflammation, Data types - Address	Altered Intercellular Communication	Inflammation interacted with AD pathology, such that greater MCP-1 and lower Ab42 was associated with altered microstructure in bilateral frontal and right temporal lobe and that greater MCP-1 and greater P-Tau181 was associated with altered microstructure in precuneus.	26836182
Inflammation, Damage, Data types - Address	Altered Intercellular Communication	Inflammation may play a role in neural damage in preclinical AD.	26836182
Airway structure	Altered Intercellular Communication	Antiviral type I IFN production is impaired in those with neutrophilic airway inflammation and in those prescribed high doses of inhaled corticosteroids.	26836898
allergic inflammation	Altered Intercellular Communication	SP-D also regulates allergic inflammation and promotes the removal of apoptotic cells.	26836907
Inflammation, Inflammatory disorder	Altered Intercellular Communication	However, associating inflammatory diseases with specific microbial members of the microbiota is challenging, because clinically detectable inflammation and its treatment can alter the microbiota's composition.	26837003
Inflammation, Chronic disease	Altered Intercellular Communication	Because low-grade inflammation may precede chronic diseases, following an overall healthy lifestyle may help lower risk of these diseases.	26838054
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Biomarkers of inflammation and risk of cardiovascular events in anticoagulated patients with atrial fibrillation.	26839066
Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding, Cerebrovascular accident	Altered Intercellular Communication	Atrial fibrillation (AF) is a risk factor for stroke and mortality and the prothrombotic state has been linked to inflammation.	26839066
Inflammation, Fibrous, Necrosis	Altered Intercellular Communication	Symptomatic patients had a larger volume of embolic debris, mean particle size, and the biomarkers associated with inflammation, necrotic core, and diminished fibrous cap.	26839124
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The IL6/STAT3 axis promotes inflammation, angiogenesis, and cancer.	26839145
Inflammation, Atrial Fibrillation by ECG Finding, Coronary Artery Disease, Endothelial dysfunction, Atrial Fibrillation	Altered Intercellular Communication	Atrial fibrillation (AF) can be associated with an increased risk of developing coronary artery disease (CAD) due to mechanisms of inflammation, endothelial dysfunction and adverse atrial remodelling.	26839165
Creutzfeldt-Jakob disease	Altered Intercellular Communication	By contrast, human growth hormone-associated cases of iatrogenic CJD (iCJD) in the United Kingdom (UK) are associated with exposure to an exogenous source of PrP(Sc).	26840342
Inflammation, Chronic Kidney Insufficiency, Atrial Fibrillation, Chronic Kidney Diseases	Altered Intercellular Communication	In this study, we examined the association between inflammation and AF in 3,762 adults with CKD, enrolled in the Chronic Renal Insufficiency Cohort (CRIC) study.	26840403
Anemia of chronic disease, Anemia, Chronic disease	Altered Intercellular Communication	Its cause is multifactorial and mostly associated with absolute iron deficiency (iron deficiency anemia) and/or functional iron deficiency (inflammation anemia or anemia of chronic disease).	26840464
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	A significant association was observed between s1m1cagA+ strains and a higher degree of inflammation, neutrophil activity and development of intestinal metaplasia.	26840466
Vasculitis, Communicable Diseases	Altered Intercellular Communication	We stress usefulness of this method in large vessel inflammation and infection.	26841377
vascular inflammations, Infection	Altered Intercellular Communication	The literature exploration was focusing on vascular inflammation and infections and 18-FDG PET.	26841377
Inflammation, Atherosclerosis, Plaque, Atherosclerotic	Altered Intercellular Communication	From this work inflammation associated with atheromatic process and vulnerable atherosclerotic plaque we excluded.	26841377
Inflammation, Infection	Altered Intercellular Communication	18F-FGD PET/CT is a sensitive metabolic, reliable, non-invasive imaging modality suitable for diagnosis and follow-up of inflammation and infections in vascular system.	26841377
Inflammation	Altered Intercellular Communication	Toll-like receptors (TLRs) are important mediators of adipose tissue inflammation and they are able to recognize endogenous products released by damaged cells.	26841679
Inflammation, Hypertrophy	Altered Intercellular Communication	Our findings suggested that EAT hypertrophy in CAD promotes adipocyte degeneration and drives local inflammation through increased infiltration of macrophages which are mainly polarized towards an M1 state and express both TLR-2 and TLR-4.	26841679
Clinical Events Domain, Menstrual epilepsy, Epilepsy	Altered Intercellular Communication	Catamenial epilepsy (CE) is a commonly observed phenomenon among women with epilepsy, the management of which is both hormonal and non-hormonal.	26841950
Necrotizing granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	A mediastinoscopy was diagnostic as histology revealed necrotizing granulomatous inflammation and the presence of acid-fast bacilli, indicating mediastinal tuberculosis.	26842759
Chlamydia trachomatis, Conjunctivitis	Altered Intercellular Communication	Inverse relationship between microRNA-155 and -184 expression with increasing conjunctival inflammation during ocular Chlamydia trachomatis infection.	26842862
Inflammation	Altered Intercellular Communication	Alternative p38 mitogen-activated kinases (p38g and p38d) have been shown to contribute to inflammation in different diseases.	26843485
Inflammation, Fatty degeneration, Neutrophil Infiltration	Altered Intercellular Communication	We further show that neutrophil infiltration in wild-type mice contributes to steatosis development by means of inflammation and liver metabolic changes.	26843485
Refractory anemias, Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	Rheumatoid arthritis (RA) is characterized by chronic joint inflammation and associates with HLA-DRB1*04.	26844284
Edema Limbs, CTCAE 5, Inflammation, Fever, CTCAE, Shock, Calusterone, Capillary Leak Syndrome	Altered Intercellular Communication	Because fever and raised inflammation parameters are not observed in idiopathic capillary leak syndrome (SCLS; Clarkson disease), a diagnosis of SCL-like syndrome was made.Albumin solution, high-dose methylprednisolone and intravenous immunoglobulins (IVIG) infusion were administered with a rapid improvement of her clinical condition.The prompt treatment with steroids and IVIG likely prevented the life-threatening shock syndrome that can occur in SCLS, with acute hypotensive attacks, and severe limbs edema requiring fasciotomy.All clinical and laboratory findings supported autoinflammation as the underlying pathogenic mechanism of the syndrome.	26844485
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Characterization of preclinical systemic inflammation could contribute to the understanding of the biology of IBD and, ultimately, facilitate development of strategies for early disease detection and intervention.	26844874
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Subclinical levels of systemic inflammation may be a feature of an early disease state that precedes the development of symptomatic IBD.	26844874
Airway structure, Allergic asthma	Altered Intercellular Communication	Inhaled allergen increases DCs in bone marrow and trafficking of DCs into the airway, which is associated with the development airway inflammation in subjects with allergic asthma.	26844926
Inflammatory abnormality of the eye, Cornea	Altered Intercellular Communication	Based on previous studies, RGTA seems to be a promising therapeutic agent for controlling ocular surface inflammation and promoting corneal healing.	26845313
Upper Respiratory Infections	Altered Intercellular Communication	Asthma is a heterogeneous multifactorial disease that is characterized in most cases by chronic respiratory tract inflammation.	26845862
Cataract, Inflammation, Uveitis	Altered Intercellular Communication	Absolute and long-lasting control of ocular, and possibly systemic, inflammation predisposes uveitis patients to satisfactory results after cataract extraction and intraocular lens implantation.	26846356
Granulomatosis, Autoimmune Diseases, Vasculitis of large artery, Necrotizing granulomatous inflammation, Systemic Vasculitis	Altered Intercellular Communication	Granulomatosis with polyangiitis (GPA) is a rare autoimmune disease characterized by necrotizing granulomatous inflammation and small vessel vasculitis that primarily involves the upper airways, lungs, and kidneys.	26847102
vascular inflammations	Altered Intercellular Communication	In 3 of the 12 patients occult areas of vascular inflammation were identified that were not previously appreciated on usual organ screening in GPA.	26847102
Inflammation, Chronic disease	Altered Intercellular Communication	Thus, in Molina risk factors typical of both under-developed and developed countries coexist, generating a unique profile associated with inflammation, oxidative stress and chronic diseases.	26847446
Diabetes Mellitus	Altered Intercellular Communication	Older Age, Higher Body Mass Index and Inflammation Increase the Risk for New-Onset Diabetes and Impaired Glucose Tolerance in Patients on Peritoneal Dialysis.	26847585
palladium, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Traditional and uremic-related risk factors, such as older age, higher BMI, and inflammation, contribute to new-onset diabetes and impaired glucose tolerance in PD patients.	26847585
Schizophrenia	Altered Intercellular Communication	g-aminobutyric acid (GABA), the major inhibitory neurotransmitter in adult mammalian brain, plays a major role in normal brain development, and has been strongly implicated in the pathobiology of schizophrenia.	26848839
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Pretreatment and follow up biopsies were scored for inflammation, fibrosis, bile ductal injury and ductular reaction.	26849025
Data types - Address, Inflammatory disorder	Altered Intercellular Communication	Sphingolipids are widely known to have roles in the pathogenesis of inflammatory diseases, where the precise roles for sphingolipids in inflammation-associated pathogenesis of AD are not well understood.	26849355
Inflammation, Data types - Address	Altered Intercellular Communication	The results of our analysis suggest the following two prospects about inflammation in AD: (1) ceramide could play important roles in both inflammatory and anti-inflammatory pathways of AD, and (2) several factors such as Sphingomyelinase and Siglec-11 may be associated with ceramide related inflammation and anti-inflammation pathways in AD.	26849355
Nasal Polyps	Altered Intercellular Communication	Age-Related Decline of Neutrophilic Inflammation Is Associated with Better Postoperative Prognosis in Non-eosinophilic Nasal Polyps.	26849431
Dermatomyositis, Polymyositis, Myositis	Altered Intercellular Communication	Background Dermatomyositis and polymyositis (DM/PM) are inflammatory myopathies characterized by muscle inflammation/weakness.	26850074
Cerebral Amyloid Angiopathy, Inflammation	Altered Intercellular Communication	Pseudotumoral presentation of cerebral amyloid angiopathy-related inflammation.	26850981
Cerebral Amyloid Angiopathy, Inflammation	Altered Intercellular Communication	To identify the clinical and radiologic features that should raise suspicion for the pseudotumoral presentation of cerebral amyloid angiopathy-related inflammation (CAA-I).	26850981
Mycosis Fungoides, Inflammation, Lymphoma, T-Cell, Cutaneous	Altered Intercellular Communication	Sustained inflammation is a key feature of mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma (CTCL).	26851186
Stiff-Person Syndrome, Autoimmune Diseases of the Nervous System, SMS gene	Altered Intercellular Communication	Stiff person syndrome (SPS) is a rare autoimmune neurological disorder with antibodies against antigens involved in neurotransmission of gamma-aminobutyric acid (GABA).	26851693
Inflammation, Asthma	Altered Intercellular Communication	Our data underline a disconnect between clinical features and underlying inflammation, suggest IL-5 production is relatively steroid insensitive, and highlight the expression of YKL-40 in patients with neutrophilic inflammation and the expression of MMPs in patients with severe asthma.	26851968
Inflammation, Perforation of nasal septum	Altered Intercellular Communication	This indicates that presence of different strains of S. aureus can maintain a chronic inflammation in symptomatic nasal septal perforations.	26852671
Allergic asthma, Inflammation, Kit Ligand, human	Altered Intercellular Communication	These findings suggest that both SCF and IL-31 play an important role in mediating inflammation and enhancing severity of atopic asthma.	26853551
Inflammation, Liver damage	Altered Intercellular Communication	In the course of the UVB phototherapy, spongiosis and pleomorphy as parameters of inflammation and cellular damage did not show significant changes.	26853735
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Electrolyte abnormalities, chronic inflammation, and medication use (such as Infliximab) that are associated with IBD are all independent risk factors for QT interval prolongation.	26853794
Crohn Disease, Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Fecal calprotectin (FC) and myeloperoxidase (MPO) indicate intestinal inflammation in ulcerative colitis (UC) and Crohn's disease (CD).	26854205
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Increasing evidence supports an association between systemic inflammation and cancer development and progression.	26854438
Inflammation, Neoplasms	Altered Intercellular Communication	The neutrophil to lymphocyte ratio (NLR) is used as a basic parameter of systemic inflammation in some tumors.	26854438
Inflammatory abnormality of the eye	Altered Intercellular Communication	Severe Ocular Inflammation Following Ranibizumab or Aflibercept Injections for Age-Related Macular Degeneration: A Retrospective Claims Database Analysis.	26855278
Ocular Motility Disorders, Inflammatory abnormality of the eye	Altered Intercellular Communication	Intravitreal injections of anti-vascular endothelial growth factor (VEGF) agents including ranibizumab and aflibercept are used to treat patients with ocular disorders such as neovascular age-related macular degeneration (nAMD); however, the injections are associated with rare instances of severe ocular inflammation.	26855278
Inflammatory abnormality of the eye	Altered Intercellular Communication	This study compared severe ocular inflammation rates in patients treated with ranibizumab versus aflibercept.	26855278
Inflammatory abnormality of the eye	Altered Intercellular Communication	The primary analysis compared severe ocular inflammation event rates per 1000 injections.	26855278
Inflammatory abnormality of the eye	Altered Intercellular Communication	No significant change occurred in the rate of severe ocular inflammation claims over time following ranibizumab treatment.	26855278
Inflammation, Complete atrioventricular block, Disease remission	Altered Intercellular Communication	TGF-b signalling is activated in CHB patients with active disease, while SMAD7 is up-regulated during the resolution of inflammation after successful treatment.	26856334
Inflammation	Altered Intercellular Communication	AIH-induced spinal plasticity is inhibited by systemic inflammation in animal models.	26856344
Inflammation, Stanford Cancer Institute, Insemination, Artificial, Homologous	Altered Intercellular Communication	Since SCI is frequently associated with systemic inflammation in humans, we tested the hypothesis that pretreatment with the anti-inflammatory agent ibuprofen enhances the effects of AIH.	26856344
Inflammation, Acute Coronary Syndrome	Altered Intercellular Communication	Red cell distribution width (RDW) and mean platelet volume (MPV) are novel markers of inflammation and oxidative stress and were associated with poor clinical outcomes in acute coronary syndrome.	26857117
Inflammation, Overweight, Metabolic Syndrome X	Altered Intercellular Communication	Overweight and obese individuals have an increased risk of developing the metabolic syndrome because of subsequent chronic inflammation and oxidative stress, which the antioxidant nutrient lycopene can reduce.	26857614
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Peritoneal inflammation and fibrosis in C-reactive protein transgenic mice undergoing peritoneal dialysis solution treatment.	26857687
palladium, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Peritoneal dialysis (PD) is known to cause peritoneal inflammation and fibrosis.	26857687
palladium, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We compare the degree of peritoneal inflammation and fibrosis in wild-type (WT) and CRP-transgenic (Tg) mice after PD treatment.	26857687
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Parietal peritoneal and omental tissues were collected for the assessment of inflammation and fibrosis.	26857687
palladium, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	CRP-Tg mice have significantly more inflammation and fibrosis than WT mice after PD treatment.	26857687
palladium, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Our results suggest that CRP play a role in inflammation and fibrosis induced by PD.	26857687
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation is associated with cancer but there are conflicting reports on associations of biomarkers of inflammation with cancer risk and mortality.	26860264
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Our study suggests that inflammation is associated with cancer risk and mortality, and combining inflammatory biomarkers into a score is a robust method of elucidating this association.	26860264
Intraocular inflammation, Disease, Uveitis	Altered Intercellular Communication	The uveitis masquerade syndromes (UMS) are a group of ocular diseases that may mimic chronic intraocular inflammation.	26860883
Acute and chronic inflammation	Altered Intercellular Communication	High-Potency Topical Steroids: An Effective Therapy for Chronic Scalp Inflammation in Rapp-Hodgkin Ectodermal Dysplasia.	26861896
Inflammation, Orf virus	Altered Intercellular Communication	We also note marked similarities between this scalp inflammation and "erosive pustular dermatosis of the scalp," a condition more typically found in elderly individuals with severe scalp sun damage, and speculate about possible shared pathogenetic mechanisms.	26861896
Airway structure, Inflammatory Bowel Diseases, Intestinal Diseases	Altered Intercellular Communication	FeNO level, a marker of airway inflammation, is elevated in children with inflammatory bowel diseases irrespective of their intestinal disease activity.	26862933
Prostate carcinoma, prostatitis	Altered Intercellular Communication	Serum Autoantibodies in Chronic Prostate Inflammation in Prostate Cancer Patients.	26863016
Inflammation, Non-Malignant	Altered Intercellular Communication	Chronic inflammation is frequently observed on histological analysis of malignant and non-malignant prostate specimens.	26863016
Prostate carcinoma, prostatitis	Altered Intercellular Communication	We aimed to identify and validate prostate inflammation associated serum autoantibodies in prostate cancer patients and evaluate the expression of corresponding autoantigens.	26863016
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Radical prostatectomy specimens of prostate cancer patients (N = 70) were classified into high and low inflammation groups according to the amount of tissue infiltrating lymphocytes.	26863016
Prostatic Neoplasms	Altered Intercellular Communication	All three autoantigens were differentially expressed in primary and/or castration resistant prostate tumors when analyzed in an inflammation-independent tissue microarray.	26863016
prostatitis	Altered Intercellular Communication	This supports evaluation of autoantibodies as non-invasive markers for prostate inflammation.	26863016
Cessation of life, Inflammation	Altered Intercellular Communication	The long-term consequences of increased inflammation in DBD and increased cell death in DCD allografts are unknown and warrant further investigation.	26863224
Inflammatory abnormality of the eye, Stevens-Johnson Syndrome, CTCAE	Altered Intercellular Communication	A 61-year-old man developed bilateral symblephara and severe ocular surface inflammation from Stevens-Johnson syndrome/TEN secondary to allopurinol.	26863497
Ventricular Arrhythmia, CTCAE 5.0, Coronary Artery Disease, Metabolic Syndrome X	Altered Intercellular Communication	Inflammation markers are associated with metabolic syndrome and ventricular arrhythmia in patients with coronary artery disease.	26864064
Inflammation, Coronary Artery Disease, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a major role in the development and progression of atherosclerosis and coronary artery disease (CAD).	26864064
Ventricular Arrhythmia, CTCAE 5.0, Inflammation	Altered Intercellular Communication	Their strong association with life-threatening ventricular arrhythmia emphasizes the proarrhythmic role of inflammation in the increased cardiovascular risk of CAD patients.	26864064
Crohn Disease, Opportunistic Infections	Altered Intercellular Communication	Since his paradoxical inflammations were not severe and opportunistic infections were excluded, IFX was cautiously continued for refractory Crohn's disease.	26864464
Inflammation, Blood Vessel	Altered Intercellular Communication	The coexistence of increased obesity-related subclinical inflammation and decreased antioxidant capacity can be observed even in prepubescence, and may eventually increase the risk of long-term vascular damage.	26865084
Inflammation, Tissue Congestion, Chronic heart failure, Anorexia, Ventricular Dysfunction, Cachexia	Altered Intercellular Communication	Intestinal congestion and right ventricular dysfunction: a link with appetite loss, inflammation, and cachexia in chronic heart failure.	26865478
Inflammation, Cachexia	Altered Intercellular Communication	Logistic regression analysis showed that BWT was associated with cachexia, even after adjusting for cardiac function, inflammation, and stages of HF (odds ratio 1.4, 95% CI: 1.0-1.8; P-value = 0.03).	26865478
Dermatitis, Atopic, Pruritus, Inflammation, physiopathological	Altered Intercellular Communication	Atopic dermatitis is a common pruritic skin disease in which barrier dysfunction and cutaneous inflammation contribute to pathogenesis.	26865566
Sialadenitis, Fibrosis Assessment	Altered Intercellular Communication	This dysfunction was associated with more pronounced labial salivary glandular inflammation but not fibrosis.	26867144
Inflammation, HIV Infections, Atherosclerosis, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	Persistent inflammation and immune activation has been hypothesized to contribute to increased prevalence of subclinical atherosclerosis and cardiovascular disease (CVD) risk in patients with chronic HIV infection.	26867220
Pain Distress Question, No ocular symptoms, Inflammatory abnormality of the eye, Lacrimation, Pruritus	Altered Intercellular Communication	The initial ocular symptoms prior to the use of TEM were mainly those of ocular surface inflammation: tearing (77.4%), redness (74.9%), itchiness (71.6%) and pain (70.3%).	26867254
Interstitial inflammation	Altered Intercellular Communication	A renal biopsy was performed and the pathology revealed viral cytopathic changes in the tubular epithelium with interstitial inflammation.	26867385
Vasculitis, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic disease	Altered Intercellular Communication	According to previous studies, sulodexide suppresses intravascular inflammation when used in patients with chronic venous disease (CVD).	26868135
APP gene, Inflammation, Asthma, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Both asthma and abdominal aortic aneurysms (AAA) involve inflammation.	26868210
Inflammation	Altered Intercellular Communication	Surgical intervention should be performed in a quiescent period of disease if possible given that biological inflammation at the time of intervention increases the complication rate.	26870600
Pneumonitis	Altered Intercellular Communication	Delayed clearance of the bacteria and stronger lung inflammation observed in infected CS-exposed mice were associated with an altered production of IL-17 and IL-22 by innate immune cells.	26870795
Microalbuminuria, Inflammation	Altered Intercellular Communication	Exposure to PM, VOCs and PAHs in indoor air and presence of urinary PAHs metabolites may lead to inflammation, which can cause microalbuminuria in kitchen workers, as observed in the present study.	26871707
Arterial Stiffness, HD Term Type, Inflammation	Altered Intercellular Communication	In HD, inflammation is one of the major causes of increased arterial stiffness.	26871812
Inflammation, peripheral blood	Altered Intercellular Communication	We analyzed clinical test data pertaining to peripheral blood T cells, antibodies, inflammation markers, and cerebral spinal fluid (CSF) completed during the disease onset phase and 5 years following diagnosis.	26871820
Intestinal metaplasia, Inflammation, Atrophic	Altered Intercellular Communication	Scores for chronic inflammation and activity declined significantly (P<0.001) 3 months after treatment, whereas those for atrophy and intestinal metaplasia showed no significant change.	26871968
Hyperlipidemia, Disorder of soft tissue, Diabetes Mellitus, Icterus, Acute Coronary Syndrome, Hepatobiliary Disorder, Traumatic injury, Malignant Neoplasms, Acute and chronic inflammation, Kidney Failure	Altered Intercellular Communication	Patients with any condition (diabetes, icterus, hyperlipidemia, physical, or surgical trauma, acute coronary syndrome, pregnancy, renal insufficiency, liver disease, malignancy, collagen tissue disease, chronic or acute inflammation, drug use affecting thrombocyte function) that could affect plasma VWF antigen or ADAMTS-13 levels were excluded.	26872106
Inflammation, Acute inflammation	Altered Intercellular Communication	A high-fat meal (HFM) induces an increase in blood lipids (postprandial lipemia; PPL), systemic inflammation, and acute airway inflammation.	26872295
Airway structure, Inflammation	Altered Intercellular Communication	Our purpose was to determine the effects of an acute bout of exercise on airway inflammation post-HFM and to identify whether any protective effect of exercise on airway inflammation was associated with a reduction in PPL or systemic inflammation.	26872295
Airway structure, Lipemia - observation	Altered Intercellular Communication	In summary, an acute bout of moderate-intensity exercise performed 12 h prior to an HFM did not change postprandial airway inflammation or lipemia in healthy, 18- to 29-year-old men.	26872295
Inflammation, Chronic disease	Altered Intercellular Communication	Both self-rated health (SRH) and inflammation are implicated in chronic diseases and premature mortality.	26872420
Uterine Fibroids	Altered Intercellular Communication	Traditional management with high-dose hormonal regimens may not be as effective when used in women with fibroids.	26872761
Inflammation, Pancreatic carcinoma	Altered Intercellular Communication	Basophil Recruitment into Tumor-Draining Lymph Nodes Correlates with Th2 Inflammation and Reduced Survival in Pancreatic Cancer Patients.	26873846
Inflammation, Neoplasms, Pancreatic carcinoma	Altered Intercellular Communication	Our results show how basophils recruited and activated in TDLNs under the influence of the tumor microenvironment regulate tumor-promoting Th2 inflammation in PDAC, helping in illuminating a key element of the immune milieu of pancreatic cancer.	26873846
Peripheral Vascular Diseases, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	A low body-mass index, peripheral arterial disease, chronic kidney disease and inflammation were predictive for 3-year all-cause mortality.	26874209
Inflammation, Disease remission, Ulcerative Colitis	Altered Intercellular Communication	We evaluated the performance of blood and faecal biomarkers for differentiating between endoscopic inflammation and mucosal healing, and clinically active disease and sustained clinical remission, and determined the predictive value for a flare in patients with ulcerative colitis [UC].	26874351
Inflammation, Disease remission	Altered Intercellular Communication	Median levels for active disease confirmed by EI [n = 35] vs clinical remission with endoscopic inflammation [n = 37] vs mucosal healing [n = 107] for FLA were 44/37/4 ug/g, CAL 25/20/10 ug/g [both p < 0.0001], PMN-e 0.06/0.03/0.02 ug/g, CRP 0.7/0.2/0.2mg/dl [both p < 0.001], and WBC 7.0/6.5/6.4/nl [p = 0.1].	26874351
Histiocytes, Inflammation, Arteritis	Altered Intercellular Communication	T-lymphocytic inflammation with little neutrophil and histiocyte infiltration may be a pathological feature of necrotizing arteritis observed in pulmonary sequestration.	26874730
Inflammation, Impaired cognition	Altered Intercellular Communication	Dietary pattern, inflammation and cognitive decline: The Whitehall II prospective cohort study.	26874911
Inflammation, Impaired cognition	Altered Intercellular Communication	Low-grade inflammation appears to play an etiological role in cognitive decline.	26874911
Inflammation, Impaired cognition	Altered Intercellular Communication	We aimed to investigate dietary patterns associated with inflammation and whether such diet is associated with cognitive decline.	26874911
Steatohepatitis, Injury of liver, Inflammation	Altered Intercellular Communication	This, however, was more pronounced upon long-term ALA intake, leading to hepatic steatosis and liver injury, as indicated by increased inflammation and disruption of the general hepatic architecture.	26876280
Inflammation, Plaque, Atherosclerotic, Atherosclerosis	Altered Intercellular Communication	The presence of bacteria and other microorganisms in atherosclerotic plaque has long been known, however, the cause of chronic inflammation and the role of bacteria/viruses in atherosclerosis have not been studied in detail.	26878370
Inflammation, atherosclerotic	Altered Intercellular Communication	The objective of this study was to clarify the cause of the chronic inflammation within atherosclerotic plaques, and determine if any bacteria and/or viruses are involved in the inflammatory pathway.	26878370
Inflammation, Plaque, Atherosclerotic, Atherosclerosis	Altered Intercellular Communication	While the presence of bacterial biofilm structures in atherosclerotic plaque does not prove that biofilm is the proximate cause of atherosclerosis, it could contribute to the persistent inflammation associated with it.	26878370
Neuronal degeneration, Inflammation, palladium, Nerve Degeneration	Altered Intercellular Communication	CSF biomarkers reflecting Lewy body pathology and neurodegeneration (a-synuclein), neuronal degeneration (tau, phosphorylated tau, and neurofilament light), and inflammation (YKL-40) increase significantly over 2 years in PD.	26878815
Autoimmune Diseases, Inflammation, Juvenile Myelomonocytic Leukemia	Altered Intercellular Communication	Chronic inflammation and autoimmunity as risk factors for the development of chronic myelomonocytic leukemia?	26879691
Autoimmune Diseases, Inflammation, Juvenile Myelomonocytic Leukemia, Leukemia, Myelomonocytic, Chronic	Altered Intercellular Communication	In this study, we investigate if chronic inflammation and autoimmunity might be related to the development of chronic myelomonocytic leukemia (CMML).	26879691
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Subjects with a history of chronic inflammation or autoimmune disorders were retrieved and odds ratios (ORs) calculated.	26879691
Sepsis, Inflammation, Communicable Diseases	Altered Intercellular Communication	Sepsis induces inflammation in response to infection and is a major cause of mortality and hospitalization in children.	26880005
Inflammation, Obesity	Altered Intercellular Communication	Obesity induces chronic inflammation leading to many clinical manifestations.	26880005
Inflammation, Metabolic Syndrome X, Capsulitis	Altered Intercellular Communication	Adhesive capsulitis: An age related symptom of metabolic syndrome and chronic low-grade inflammation?	26880627
Inflammation, Primary malignant neoplasm, Pain Distress Question, Demographics Domain, Nervous System Physiological Phenomena, Metabolic Syndrome X, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus, Obesity	Altered Intercellular Communication	Obesity and metabolic syndrome, which are strongly associated with chronic low grade inflammation, are becoming increasingly understood to underlie a raft of morbid states including upper limb pain syndromes, diabetes (DM), cardiovascular disease (CVD), cancer and central nervous system dysfunction and degeneration.	26880627
Inflammation, Demographics Domain, Metabolic Syndrome X, Fibrosis Assessment, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	The hypothesis argues that similar to DM and CVD, the inflammation and capsular fibrosis seen in AC is precipitated by metabolic syndrome and chronic low grade inflammation.	26880627
Inflammation, polyps, Cutaneous Precancerous Condition, "Reinkes edema", Cyst, Leukoplakia	Altered Intercellular Communication	The fifty-two tissue specimens, including 10 samples of cancerous lesion, 10 adjacent normal tissue, 10 chronic inflammation, eight cyst, three leukoplakia, four polyp, and seven Reinke's edema, were obtained during laryngological procedures.	26881757
Inflammation	Altered Intercellular Communication	Our results reveal that more severe inflammation, based on high levels of IL-6, is associated with lower expression of VPAC1 (p<0.001) and conversely with increased expression of VPAC2 (p<0.001).	26881970
Inflammation	Altered Intercellular Communication	Patients with more severe inflammation and higher disease activity show lower levels of VPAC1 expression, which is associated with patient-reported impairment.	26881970
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Of the 33 children, 28 (85%) had gut mucosal inflammation, mostly affecting the colon (80%).	26882369
Eosinophilic inflammation	Altered Intercellular Communication	There was a negative association with the use of immunomodulators and the presence of eosinophil inflammation.	26882369
Juvenile arthritis, Inflammation, Colitis	Altered Intercellular Communication	The majority of children with JIA and GI symptoms have histological evidence of mild nonspecific inflammation, but some having active colitis and prominent eosinophil infiltrate.	26882369
Cessation of life, Inflammation, Brain Injuries	Altered Intercellular Communication	Dysregulated inflammation post-TBI exacerbates secondary brain injury and contributes to unfavorable patient outcomes including death.	26883121
Multimorbidity, Inflammation, Chronic disease	Altered Intercellular Communication	Multimorbidity is the co-occurrence of chronic diseases associated with low-grade chronic inflammation of connective tissue.	26883337
Multimorbidity	Altered Intercellular Communication	The alterations in plasma FN molecular status were associated with micro-inflammation and micro-coagulation, as well as multimorbidity of subjects and their physiological aging.	26883337
Eosinophilic Granuloma, Systemic Vasculitis	Altered Intercellular Communication	Asthma Control and Airway Inflammation in Patients with Eosinophilic Granulomatosis with Polyangiitis.	26883543
Airway structure, Rhinosinusitis, Asthma	Altered Intercellular Communication	Although low systemic disease activity was documented in the large majority of patients, poorly controlled asthma and rhinosinusitis with eosinophilic airway inflammation were demonstrated in almost all patients.	26883543
Inflammation, Mycoses, oral fungal infection	Altered Intercellular Communication	Since fungal oral infections have not yet been studied in this respect, the aim of our study is to determine whether the local inflammation caused by oral fungal infection of the palatal tissue (denture stomatitis-DS) is associated with the systemic inflammatory response.	26883670
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Chronic low-grade inflammation contributes to the pathology and complications of type 2 diabetes (T2D).	26883847
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	We examined the ability of IL10 to inhibit inflammation in human T2D immune cells and explored underlying mechanisms using macrophage models.	26883847
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	This data supports the idea that IL10 hyporesponsiveness may contribute to chronic inflammation in T2D.	26883847
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	These novel findings suggest that strategies aimed to overcome IL10 hyporesponsiveness may hold therapeutic potential for reducing inflammation in T2D.	26883847
Acute Kidney Injury, CTCAE, Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	Systemic inflammation is involved in the development of acute kidney injury (AKI) after cardiac surgery with cardiopulmonary bypass (CPB).	26884251
Inflammation, Specimen Type - Fistula, Cellulitis	Altered Intercellular Communication	Dermoid cyts are often innocent, however complications such as inflammation of the fistula or preseptal cellulitis are occasionally seen.	26885559
Inflammation	Altered Intercellular Communication	Considering the important roles that SIRT6 plays in the cardiovascular system, inflammation, and lipid and cholesterol metabolism, genetic variants were hypothesized to contribute to MI development.	26886147
Blindness, Inflammation	Altered Intercellular Communication	Although not individually significant, transmural inflammation (p=0.11), luminal thrombus (p=0.17) and giant cells (p=0.20) were more frequent in patients who suffered blindness, whereas fragmentation of the internal elastic lamina (p=0.04), and intimal thickening (p=0.02) were more frequent in patients without blindness.	26886472
Inflammation	Altered Intercellular Communication	The presence of giant cells was associated with transmural inflammation (p=0.06), jaw claudication (p=0.02), and higher inflammatory markers.	26886472
Aggressive course, Inflammation	Altered Intercellular Communication	Giant cells are strongly associated with jaw claudication and systemic markers of inflammation, perhaps reflecting more acute and aggressive disease.	26886472
Inflammation, Abnormality of mitochondrial metabolism	Altered Intercellular Communication	Mitochondrial dysfunction may play an important role in abnormal glucose metabolism and systemic inflammation.	26886611
Ichthyosis Bullosa of Siemens, Liver carcinoma	Altered Intercellular Communication	A Novel and Validated Inflammation-Based Score (IBS) Predicts Survival in Patients With Hepatocellular Carcinoma Following Curative Surgical Resection: A STROBE-Compliant Article.	26886627
Inflammation, Ichthyosis Bullosa of Siemens, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	As chronic inflammation is involved in the pathogenesis and progression of hepatocellular carcinoma (HCC), we investigated the prognostic accuracy of a cluster of inflammatory scores, including the Glasgow Prognostic Score, modified Glasgow Prognostic Score, platelet to lymphocyte ratio, Prognostic Nutritional Index, Prognostic Index, and a novel Inflammation-Based Score (IBS) integrated preoperative and postoperative neutrophil to lymphocyte ratio in 2 independent cohorts.	26886627
Chronic liver disease, Hepatitis	Altered Intercellular Communication	Natural killer (NK) cells are important mediators of liver inflammation in chronic liver disease.	26887815
Refractory anemias, Osteopenia	Altered Intercellular Communication	In conclusion, gene expression of human osteocyte-specific proteins and cytokines was affected by RA-serum, and exogenous recombinant cytokines treatment suggesting that osteocytes could provide a new target to prevent systemic inflammation-induced bone loss in RA.	26887974
Inflammation, Neuropathy	Altered Intercellular Communication	These data suggest that ML may contribute to TNF-mediated inflammation and focal demyelination by rendering SCs more sensitive to TNF within the nerves of patients with leprous neuropathy.	26888306
Inflammation, Gout	Altered Intercellular Communication	Although the genetic variants in IL-17 we studied in this research do not appear to be involved in the development of gout in male Chinese Han individuals, the IL-17 cytokine family may participate in gouty inflammation in an undefined way, which requires further validation.	26890073
Inflammation, Coronary heart disease	Altered Intercellular Communication	This study evaluates the relationship between locally activated PMCs and intracoronary inflammation in stable and unstable coronary disease.	26890234
Fibrosis Assessment, Hepatitis, FAM126A gene	Altered Intercellular Communication	The risk to develop HCC increases with the severity of liver inflammation and hepatic fibrosis.	26890368
Cessation of life, Encephalitis, Inflammation, Illness (finding)	Altered Intercellular Communication	Encephalitis, a brain inflammation leading to severe illness and often death, is caused by >100 pathogens.	26890626
Inflammation, Dry Eye Syndromes	Altered Intercellular Communication	Inflammation aggravated by vitamin D deficiency results in an altered epithelial profile, Bowman layer damage, recruitment of dendritic cells, and altered subbasal nerve plexus features in patients with chronic dry eye disease.	26890669
Inflammation	Altered Intercellular Communication	Inflammation, represented by CD8 T-cell levels, and persistent C-reactive protein elevation are independent predictors of angiographic restenosis and should therefore be closely monitored in HIV patients undergoing PCI.	26891035
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The reciprocal links between synaptophysin serum levels and the prevalence of metabolic syndrome according to selected low-grade inflammation indices and age-related androgen serum level changes in men.	26891429
Celiac Disease	Altered Intercellular Communication	Coeliac disease is a chronic immune-mediated inflammation of the small intestine elicited by the gluten ingestion in genetically susceptible people.	26891431
Inflammation, Communicable Diseases, Chronic otitis, Prolonged, cyclophosphamide/methotrexate/vincristine protocol	Altered Intercellular Communication	Chronic otitis media (COM) describes a variety of symptoms and physical findings that result from prolonged damage to the middle ear by infection and inflammation.	26891542
vascular inflammations, Mucopolysaccharidosis I	Altered Intercellular Communication	In a model of vascular inflammation, mCRP induced endothelial shedding of MPs and was proinflammatory, while pCRP was anti-inflammatory.	26891844
Oropharyngeal, Inflammation, Squamous cell carcinoma of the head and neck	Altered Intercellular Communication	Systemic inflammation is an independent predictive marker of clinical outcomes in mucosal squamous cell carcinoma of the head and neck in oropharyngeal and non-oropharyngeal patients.	26892430
vascular inflammations, Calcification of coronary artery	Altered Intercellular Communication	Association of pooled cohort risk scores with vascular inflammation and coronary artery calcification in Korean adults.	26892510
vascular inflammations, Calcinosis	Altered Intercellular Communication	The relationship of this new risk scoring system with vascular inflammation and calcification has yet to be examined.	26892510
vascular inflammations, Calcinosis	Altered Intercellular Communication	The pooled cohort risk equation exhibited significant positive correlations with vascular inflammation but not with calcification in Asian subjects without CVD, suggesting that this novel risk equation may detect early inflammatory changes preceding the structural modification of vessel walls.	26892510
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Metabolic Syndrome X	Altered Intercellular Communication	However, metabolic syndrome is often associated with non-alcoholic fatty liver disease, which leads to liver fibrosis and inflammation that may decrease VLDL production.	26892520
Inflammation, Impaired cognition, "Alzheimers Disease	Altered Intercellular Communication	The Independent Role of Inflammation in Physical Frailty among Older Adults with Mild Cognitive Impairment and Mild-to-Moderate Alzheimer's Disease.	26892578
Arterial Stiffness, Calcified (qualifier)	Altered Intercellular Communication	Influence of Thoracic Aortic Inflammation and Calcifications on Arterial Stiffness and Cardiac Function in Older Subjects.	26892585
Arterial Stiffness, Calcified (qualifier), Hypertensive (finding)	Altered Intercellular Communication	To determine the influence of thoracic aortic inflammation and calcifications on arterial stiffness and cardiac function in hypertensive and normotensive older subjects.	26892585
Calcinosis	Altered Intercellular Communication	Local thoracic aortic inflammation and calcification were measured by 18 F-fluorodeoxyglucose positron emission tomography/computed tomography imaging.	26892585
Calcified (qualifier), Inflammation	Altered Intercellular Communication	In the overall population, calcifications of the thoracic descending aorta and inflammation of the ascending aorta accounted for respectively 18.1% (p=0.01) and 9.6% (p=0.07) of AoPWV variation.	26892585
Calcified (qualifier), Inflammation	Altered Intercellular Communication	Individuals with high levels of calcifications and/or inflammation had higher AoPWV (p=0.003).	26892585
Inflammation, Hypertension, CTCAE, Calcified (qualifier)	Altered Intercellular Communication	This study highlights the importance of local ascending aortic inflammation as a potential major actor in the determination of PPA while calcifications and hypertension are more linked to AoPWV.	26892585
Inflammation	Altered Intercellular Communication	Assessment of PPA in the very elderly could provide complementary information to improve diagnostic and therapeutic strategies targeting ascending aortic inflammation.	26892585
ARCN1 gene, Inflammation	Altered Intercellular Communication	Chronic inflammation associated with COPD is thought to contribute to this risk.	26893553
ARCN1 gene, Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Exacerbations of COPD are associated with a rise in inflammation, suggesting that there may be an association between exacerbation frequency and the risk of stroke.	26893553
Inflammation, Fibrosis Assessment, Lung diseases	Altered Intercellular Communication	Pulmonary disease is the main cause of morbidity and mortality in cystic fibrosis (CF) patients due to exacerbated inflammation.	26894321
Pneumonitis	Altered Intercellular Communication	Overall, sulindac decrease lung inflammation by a mechanism independent of cycolooxygenase.	26894321
Inflammation, Aspects of mortality statistics	Altered Intercellular Communication	Actigraphy- and Polysomnography-Measured Sleep Disturbances, Inflammation, and Mortality Among Older Men.	26894325
Inflammation	Altered Intercellular Communication	Medical and life-style factors also substantially attenuated most sleep-mortality associations, suggesting complex relations between sleep, inflammation, and disease.	26894325
Liver and Intrahepatic Biliary Tract Carcinoma	Altered Intercellular Communication	Preoperative biliary drainage-related inflammation is associated with shorter survival in biliary tract cancer patients.	26894390
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	An association between inflammation and patient prognosis has been reported in various types of cancer.	26894390
Liver and Intrahepatic Biliary Tract Carcinoma	Altered Intercellular Communication	Preoperative biliary drainage-related inflammation was an independent prognostic factor for shorter OS in biliary tract cancer patients.	26894390
Inflammation, Bell Palsy	Altered Intercellular Communication	Inflammation is thought to play an important role in the pathogenesis of Bell's palsy (BP).	26894418
Granulomatosis, Orofacial, Granulomatous inflammation	Altered Intercellular Communication	Orofacial granulomatosis (OFG) is characterized by granulomatous inflammation in the orofacial region.	26894770
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Component steatosis, inflammation and ballooning scores, and fibrosis staging were correlated with SWV, and diagnostic accuracy of ARFI for fibrosis was assessed.	26895403
Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Obesity	Altered Intercellular Communication	The mean SWV was neither significantly different nor correlating with the obesity classes based on body mass index (BMI), steatosis grades, inflammation grades, ballooning grades, and fibrosis stages of NAFLD.	26895403
Inflammation, Asthma	Altered Intercellular Communication	Periostin is considered to be a marker of eosinophilic inflammation in patients with asthma.	26895432
Inflammation, Aortic Stiffness	Altered Intercellular Communication	There appears to be no causal relationship between endothelial function and aortic stiffness, suggesting that they occur in parallel, although they may share common risk factors such as inflammation.	26896473
Rheumatoid Arthritis, Endothelial dysfunction	Altered Intercellular Communication	Rheumatoid arthritis is a systemic inflammatory condition associated with increased cardiovascular risk that may be due to underlying endothelial dysfunction and subsequent aortic stiffening.	26896473
Fibrosis Assessment, Hepatitis, Chronic, Lymphoproliferative Disorder of the Skin	Altered Intercellular Communication	Taken together, our results demonstrate that infiltrating monocytes may play a pathological role in exacerbating chronic liver inflammation and fibrosis in CLD.	26896599
Fibrosis Assessment, Hepatitis, Lymphoproliferative Disorder of the Skin	Altered Intercellular Communication	MCP-1 may be involved in the monocyte infiltration and progression of liver inflammation and fibrosis in CLD.	26896599
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Regarding the stage of fibrosis, patients with advanced fibrosis were older and had more insulin resistance and more inflammation compared with patients that had mild fibrosis.	26896689
Fibrosis of pancreas, Pancreatitis, Inflammation, Exocrine Pancreas Cell	Altered Intercellular Communication	Chronic pancreatitis (CP), a common background of PDAC occurrence, is morphologically defined as progressive pancreatic fibrosis and inflammation accompanied by pancreatic exocrine cell atrophy.	26897254
ANOPHTHALMIA AND PULMONARY HYPOPLASIA, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	We recently found that inflammation and fibrosis are independent characteristic histological changes in noncancerous lesions in PDAC patients despite the absence of a past history of clinical CP.	26897254
Inflammation, Skin Infection, CTCAE, Cellulitis	Altered Intercellular Communication	Hence, AAT may have a role in the healing process in chronic and acute inflammation including skin infection, such as cellulitis.	26897780
Inflammation, Cellulitis	Altered Intercellular Communication	This possibly suggests a role AAT activity may have in the inflammation cascade in patients with cellulitis.	26897780
Inflammation, Dental caries, Pain Distress Question	Altered Intercellular Communication	Furthermore, when pathological processes such as caries affect teeth and produce inflammation of the pulp, the pain experienced can be quite intense and debilitating.	26898566
Inflammation, Squamous cell carcinoma of the head and neck, Neoplasms	Altered Intercellular Communication	In patients with HNSCC, reduced expression of ADO may contribute to excessive inflammation and tumor growth.	26898925
Inflammation, Periodontitis, Metabolic Syndrome X, palladium, MS gene	Altered Intercellular Communication	Metabolic Syndrome (MS) and chronic oral condition (periodontitis [PD]) are state of inflammation.	26899213
Inflammation, Neoplasms	Altered Intercellular Communication	Systemic inflammation is a key factor in tumor growth.	26899471
Inflammation	Altered Intercellular Communication	C-reactive protein and albumin are parameters of systemic inflammation from the Glasgow Prognostic Score (GPS).	26899471
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Clusterin (CLU) is recognized as a secreted protein that is related to the processes of inflammation and immunity in the pathogenesis of Alzheimer's disease (AD).	26899953
Inflammation	Altered Intercellular Communication	This trend may be affected by the secular increase in height and the sharp upswing in adolescent overweight; these drive increased insulinlike growth factor 1 and chronic inflammation, which may play an etiologic role.	26900677
Inflammation, Acute-On-Chronic Liver Failure, Septicemia, CRNKL1 wt Allele, Bacterial peritonitis, Encephalopathy, CTCAE 5.0	Altered Intercellular Communication	BactDNA was associated with spontaneous bacterial peritonitis and blood stream infections (SBP/BSI), acute-on-chronic liver failure (ACLF), encephalopathy and markers of inflammation.	26901072
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Increased inflammation might be a risk factor of AEMD and LA mechanical dysfunction in ESRD patients.	26905405
Inflammation, Pancreatic carcinoma, Diabetes Mellitus	Altered Intercellular Communication	Epidemiologic studies show strong associations between pancreatic cancer (PC) and inflammatory stimuli or conditions such as cigarette smoking and diabetes, suggesting that inflammation may play a key role in PC.	26905587
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Studies of dietary patterns and cancer outcomes also suggest that diet might influence an individual's risk of PC by modulating inflammation.	26905587
Choroiditis	Altered Intercellular Communication	The L/S ratio measured by binarisation of EDI-OCT images was predictive factor for the progression of PPA, subsequent chronic recurrences and total dose of corticosteroid, and may serve as a marker for degree of choroidal inflammation in the VKH disease.	26906951
Colorectal Carcinoma	Altered Intercellular Communication	Usefulness of Inflammation-Based Prognostic Score in Patients Undergoing Lung Metastasectomy for Colorectal Carcinoma.	26908239
Acute Kidney Injury, CTCAE, Negative Regulation of Cell Cycle	Altered Intercellular Communication	These divergent patterns of inflammatory signals are consistent with cell cycle arrest (TIMP-2, IGFBP7) and relative protection from acute kidney injury after imaging and stenting.	26908767
Inflammation, Acute lymphocytic leukemia	Altered Intercellular Communication	ERG is a key regulator of cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis and has recently been found to be overexpressed in acute myeloid and lymphoblastic leukemia.	26909589
Sialadenitis, Inflammation	Altered Intercellular Communication	During intraoperative consultation, the lesions were identified as benign, atrophic salivary gland with chronic inflammation, or sialadenitis with atypical glands.	26909791
Chronic sclerosing sialadenitis	Altered Intercellular Communication	Chronic sclerosing sialadenitis (CSS) is a benign chronic inflammatory condition of the salivary gland.	26909791
Inflammation, Fibrosis Assessment, Neurogenic arthropathy, Ulcer	Altered Intercellular Communication	Three significant local conditions influencing selection and transfer of the flap include (1) distally located forefoot ulcers, (2) extensive subcutaneous fibrosis secondary to frequent inflammation, and (3) Charcot arthropathy.	26910652
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	In middle-aged and older samples, perceived subjective socioeconomic status (SSS) is a marker of social rank that is associated with elevated inflammation and cardiovascular disease risk independent of objective indicators of SES (oSES).	26910797
Inflammation, Stenosis Morphology, Necrosis	Altered Intercellular Communication	Biliary vessel pathology due to alveolar echicococcosis (AE) results in variable combinations of stenosis, necrosis and inflammation.	26910822
Inflammation, Intervertebral Disc Degeneration, DGCR2 gene	Altered Intercellular Communication	P38MAPK mediates cytokine induced inflammation in nucleus pulposus (NP) cells and involves in multiple cellular processes which are related to intervertebral disc degeneration (IDD).	26911458
Inflammation, DGCR2 gene	Altered Intercellular Communication	Hence, Our study suggests that selectively targeting p38 isoforms could ameliorate the inflammation in IDD and regard IDD progression.	26911458
Granulomatous inflammation	Altered Intercellular Communication	However, among nodes with granulomatous inflammation, ca-TBFB exhibited higher sensitivity (90%) than TBNA (33%).	26912301
Inflammation, Amyloidosis, Data types - Address	Altered Intercellular Communication	This activation, correlating positively with the amyloid load, implies a relationship between amyloidosis and inflammation in the PS2APP AD mouse model.	26912428
Inflammation	Altered Intercellular Communication	Administration of the adjuvants led to an influx of activated inflammatory cells into the muscle but to little systemic inflammation measured by serum cytokine levels.	26912628
Communicable Diseases, Inflammation, cell injury	Altered Intercellular Communication	We chose to target the inflammasome, a molecular complex capable of detecting infection and cell damage and of triggering IL-1b-driven inflammation.	26912628
Inflammation	Altered Intercellular Communication	The most common benign diagnosis was chronic inflammation (94 patients) by pericardial biopsy.	26913680
Chronic pain, Chronic inflammation	Altered Intercellular Communication	We did not experience any other mesh-related complications, such as protrusion, chronic pain, or chronic inflammation, during the follow-up period.	26913817
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The authors conclude that CK-903 is a useful adjunctive tool that will allow for a quicker, less costly, and more accurate diagnosis of LPP given its ability identify colloid bodies even in the setting of significant inflammation and fibrosis and its advantages over direct immunofluorescence of low cost, short preparation time, and lack of need for a specialized fluorescent microscope.	26913845
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Chronic activation of the complement system and induced inflammation are associated with neuropathology in Alzheimer's disease (AD).	26914463
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Final diagnosis was IgG4-RD in 28, malignancy in 29, IgG4-unrelated inflammation in 35, and undetermined cause in 2 subjects.	26914555
Inflammation, T-Cell Receptors delta-Chain	Altered Intercellular Communication	The MCP-1 concentration was markedly elevated at the second vitrectomy, implying an association between the prolonged inflammation after vitrectomy and complications, especially TRD.	26915745
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Results suggest that targeting emotion regulation may help to break the cycle between inflammation and sickness symptoms in women with breast cancer.	26916219
ARCN1 gene, Inflammation	Altered Intercellular Communication	Increased daily movement associates with reduced mortality among COPD patients having systemic inflammation.	26916560
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Emerging research demonstrates an interrelationship between systemic inflammation, physical activity and premature all-cause mortality among chronic obstructive pulmonary disease (COPD) patients.	26916560
ARCN1 gene, Inflammation	Altered Intercellular Communication	Physical activity may help to promote survival among COPD patients, particularly those with elevated inflammation.	26916560
Inflammation	Altered Intercellular Communication	The inflammatory responses evoked by artificial organs and implantation of devices like biosensors and guide wires can lead to acute and chronic inflammation, largely limiting the functionality and longevity of the devices with negative effects on patients.	26916758
Inflammation	Altered Intercellular Communication	Increased peripheral inflammation in asymptomatic leucine-rich repeat kinase 2 mutation carriers.	26917005
Inflammation	Altered Intercellular Communication	The results suggest that peripheral inflammation is higher in a percentage of subjects carrying the LRRK2 G2019S mutation.	26917005
Inflammation, Asthma	Altered Intercellular Communication	Serum periostin is a potential biomarker of response to therapies that target type 2 inflammation in asthma.	26917610
Inflammation, Neoplasm Metastasis, Appendiceal Neoplasms	Altered Intercellular Communication	Chronic inflammation masquerading as an appendiceal tumour with peritoneal metastasis: the challenge of diagnosis and the lessons learnt.	26917796
Communicable Diseases, Neoplasms	Altered Intercellular Communication	The differential diagnosis includes neoplasms, inflammatory conditions, infectious conditions, and scar.	26918968
Pain Distress Question, Pleurisy, Pneumothorax	Altered Intercellular Communication	Specifically, 0.6% was pneumothorax, 0.3% was cytotoxic agent-induced pleural inflammation, 0.5% was pain at puncture location, and 0.3% was failure of HIPEC procedure.	26919243
Parkinson Disease, Inflammation, palladium	Altered Intercellular Communication	Previous studies have suggested that chronic systemic inflammation increases the risk of Parkinson's disease (PD).	26919462
Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Positron Emission Tomography and Magnetic Resonance Imaging of Cellular Inflammation in Patients with Abdominal Aortic Aneurysms.	26919936
APP gene, Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Inflammation is critical in the pathogenesis of abdominal aortic aneurysm (AAA) disease.	26919936
APP gene, vascular inflammations	Altered Intercellular Communication	Both (18)F-FDG PET-CT and USPIO-MRI uptake identify vascular inflammation associated with AAA.	26919936
Inflammation, Fatigue	Altered Intercellular Communication	Thus, extracellular HSPs, particularly HSP90a, may signal fatigue in chronic inflammation.	26921255
Inflammation	Altered Intercellular Communication	In summary, our results suggest that IFN-a-driven, early regulatory T cell depletion contributes to the development of antiviral immunity, ultimately resulting in the resolution of type 1 inflammation.	26921346
Inflammation, Cytomegalovirus Infections, Refractory anemias, Arthritis, Immunosenescence	Altered Intercellular Communication	Considering the signs of premature T-cell immunosenescence in arthritis patients, the known effect of CMV latency on speeding up many of these signs in an age-dependent manner and the role of CMV on IFNg-mediated inflammation in healthy elderly and RA, we hypothesized that latent CMV infection accelerates TCR repertoire restriction, loss of CD28, peripheral T-cell proliferation and aberrant IFNg responses in arthritis patients.	26921739
Inflammation	Altered Intercellular Communication	Serum free light chains are reduced in endurance trained older adults: Evidence that exercise training may reduce basal inflammation in older adults.	26921802
Inflammation	Altered Intercellular Communication	These findings suggest that long-term endurance training may be beneficial in reducing basal inflammation in older adults as well as elevated FLCs present in inflammatory and autoimmune conditions, often associated with ageing.	26921802
Chronic Obstructive Airway Disease	Altered Intercellular Communication	Lack of Correlation Between Pulmonary and Systemic Inflammation Markers in Patients with Chronic Obstructive Pulmonary Disease: A Simultaneous, Two-Compartmental Analysis.	26921918
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The origin of systemic inflammation in chronic obstructive pulmonary disease (COPD) patients remains to be defined, but one of the most widely accepted hypothesis is the 'spill over' of inflammatory mediators from the lung to the circulation.	26921918
ARCN1 gene, Inflammation	Altered Intercellular Communication	To evaluate the relationship between pulmonary and systemic inflammation in COPD quantifying several inflammatory markers in sputum and serum determined simultaneously.	26921918
ARCN1 gene, Inflammation	Altered Intercellular Communication	We found no correlation between pulmonary and systemic inflammation in patients with stable COPD, suggesting different pathogenic mechanisms.	26921918
Pain Distress Question, Exophthalmos, Binocular diplopia, Inflammation	Altered Intercellular Communication	A case is presented of a right frontoethmoidal osteoma with intraorbital invasion in a 43-year-old male, who was seen in the clinic with a proptosis, retro-orbital pain, peri-palpebral inflammation, and binocular diplopia due to muscular route limitation.	26922136
Inflammation, Cholecystitis, Acute Cholecystitis	Altered Intercellular Communication	Because acute cholecystitis has a different prognosis according to the degree of inflammation, early detection and prompt operation of severe cholecystitis are critical to the success of treatment.	26922627
Diabetic Nephropathy, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Determinants of visfatin in type 2 diabetes patients with diabetic kidney disease: Relationship to inflammation, adiposity and undercarboxylated osteocalcin.	26922969
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The main determinant of visfatin in T2D patients with DKD is inflammation; in normoalbuminuric patients, a positive link to adiposity and altered glycemic control and a trend towards a negative correlation to uOC was observable; the latter relationship was evident in patients without DKD.	26922969
Depression, CTCAE	Altered Intercellular Communication	Inflammation mediates the association between fatty acid intake and depression in older men and women.	26923510
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Antioxidants and fatty acids are associated with depression and inflammation, and inflammation appears to predict depression risk; hence, the associations between these nutrients and depression may be mediated by inflammation.	26923510
Inflammation, Osteoporosis, Postmenopausal	Altered Intercellular Communication	Postmenopausal osteoporosis may be caused, in part, by oxidative stress and inflammation.	26923532
Inflammation, Venous Engorgement, Abnormality of coagulation, Liver Failure	Altered Intercellular Communication	Increased INR is an independent predictor of all-cause mortality in ADHF patients without anticoagulation, reflecting coagulation abnormalities and hepatic insufficiency, possibly through systemic inflammation, neurohormonal activation and venous congestion.	26924077
Inflammation, Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	This pathway is known to play a role in inflammation, tumor growth, invasiveness and metastasis, inhibition of apoptosis and angiogenesis.	26925639
Vascular Diseases, Inflammation, Somatic dysfunction of lower limb, Acute lymphocytic leukemia, Renal Insufficiency, Dyspnea	Altered Intercellular Communication	Heart and vascular disease (H), objectively measured lower extremity dysfunction (O), systemic inflammation (S), dyspnea (P), impaired renal function (I), and tobacco exposure (T) were independent predictors for all-cause hospitalization (ALL).	26926337
ARCN1 gene, Inflammation	Altered Intercellular Communication	In the airways of COPD subjects, fibroblast-derived PGE2 may regulate angiogenesis and inflammation through the production of VEGF and IL-8 respectively, suggesting that the increase in expression of COX-2, EP2 and EP4 observed in COPD fibroblasts may contribute to steering the role of PGE2 from homeostatic to pro-inflammatory.	26926362
Pneumonitis	Altered Intercellular Communication	CD81 and CD48 show different expression on blood eosinophils in systemic sclerosis: new markers for disease and pulmonary inflammation?	26926492
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We hypothesized that eosinophils may be activated in the peripheral circulation, thereby increasing their recruitment to affected tissues and contributing to inflammation and fibrosis.	26926492
Inflammation	Altered Intercellular Communication	In patients with short disease duration, increased CD48 expression was associated with alveolar inflammation as measured by an increased concentration of alveolar nitric oxide (r = 0.76, p = 0.003).	26926492
Sample Size Calculation, Pneumonitis	Altered Intercellular Communication	Blood eosinophils change phenotype during disease evolution in SSc, and CD48 expression may be used as a biomarker for pulmonary inflammation.	26926492
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Here, we report that in monocytes and macrophages of patients with atherosclerotic coronary artery disease (CAD), overutilization of glucose promotes excessive and prolonged production of the cytokines IL-6 and IL-1b, driving systemic and tissue inflammation.	26926996
Inflammation, physiopathological, Cardiovascular Diseases	Altered Intercellular Communication	In essence, PKM2 serves a previously unidentified role as a molecular integrator of metabolic dysfunction, oxidative stress and tissue inflammation and represents a novel therapeutic target in cardiovascular disease.	26926996
Cardiovascular Diseases	Altered Intercellular Communication	Abnormal glucose metabolism and enhanced oxidative stress accelerate cardiovascular disease, a chronic inflammatory condition causing high morbidity and mortality.	26926996
Intracerebral, Inflammation, Ischemic stroke	Altered Intercellular Communication	In summary, we provide the first histologic description of mechanically retrieved intracerebral thrombi regarding biomarkers relevant for inflammation in ischemic stroke.	26927082
Inflammation, diabetic	Altered Intercellular Communication	Associations between Vitamin B-12 Status and Oxidative Stress and Inflammation in Diabetic Vegetarians and Omnivores.	26927168
Inflammation, Crypt abscess, Superficial ulcer, Cryptitis, Exacerbation of cGVHD	Altered Intercellular Communication	In contrast, patients with any of 5 histologic features of active inflammation (erosions, cryptitis, crypt abscess, increased neutrophils, or increased eosinophils in the lamina propria) had more flares than patients without those changes (P<0.05).	26927490
Inflammatory abnormality of the eye	Altered Intercellular Communication	Syphilis, although an uncommon cause of ocular inflammation, is a highly contagious, but curable disease.	26927522
Inflammation, Idiopathic pulmonary hypertension	Altered Intercellular Communication	Chemokine CXC ligand 13 (CXCL13) has been implicated in perivascular inflammation and pulmonary vascular remodeling in patients with idiopathic pulmonary artery hypertension (IPAH).	26927848
Crohn Disease	Altered Intercellular Communication	Eosinophils Contribute to Intestinal Inflammation via Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells, CRTH2, in Experimental Crohn's Disease.	26928963
Inflammation	Altered Intercellular Communication	Eosinophils contribute to the severity of the inflammation, which is improved by a selective CRTH2 antagonist.	26928963
HD Term Type, Inflammation	Altered Intercellular Communication	One of the most important causes of ESA resistance is chronic inflammation in hemodialysis (HD) patients.	26929254
HD Term Type, Inflammation	Altered Intercellular Communication	Neutrophil/lymphocyte (NLR) ratio and platelet/lymphocyte ratio (PLR) were also found to be associated with inflammation in HD patients.	26929254
ARCN1 gene, Inflammation	Altered Intercellular Communication	This provides further evidence that COPD is a multicomponent disease, involving both airway and systemic inflammation.	26929615
physiopathological, Bladder neck obstruction	Altered Intercellular Communication	Urothelial Dysfunction, Suburothelial Inflammation and Altered Sensory Protein Expression in Men with Bladder Outlet Obstruction and Various Bladder Dysfunctions: Correlation with Urodynamics.	26930253
Inflammation, Bladder dysfunction, Bladder neck obstruction	Altered Intercellular Communication	We investigated urothelial integrity, suburothelial inflammation and the expression of sensory proteins in the bladder urothelium of male patients with bladder outlet obstruction and various bladder dysfunctions.	26930253
Inflammation, Bladder dysfunction, Bladder neck obstruction, physiopathological	Altered Intercellular Communication	Urothelial dysfunction, suburothelial inflammation, cellular apoptosis and alterations in sensory proteins are prominent in bladder dysfunction secondary to bladder outlet obstruction.	26930253
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Evidence suggests that chronic subclinical inflammation plays an important role in the pathogenesis of type 2 diabetes (T2DM).	26930607
Inflammation, Bile Ducts, Extrahepatic	Altered Intercellular Communication	Differential diagnosis between inflammation and cancer of the extrahepatic biliary tract is a complex task.	26931011
methyldopa, Inflammation	Altered Intercellular Communication	Inflammation has been implicated in age-related macular degeneration (AMD).	26931413
Acanthamoeba	Altered Intercellular Communication	Acanthamoeba and their proteins can elicit severe allergic airway inflammation in experimental mice.	26932171
Acute Kidney Tubular Necrosis, Interstitial inflammation	Altered Intercellular Communication	A relapse in the AAV was suspected but a diagnostic kidney biopsy showed acute tubular necrosis, patchy interstitial inflammation, and calcium phosphate deposits.	26932179
Cholecystitis, Chronic cholecystitis	Altered Intercellular Communication	Gall stones (GS) cause inflammation of the gall bladder (GB) i.e., chronic cholecystitis (CC) and xantho-granulomatous cholecystitis (XGC) which can result in a thick walled GB (TWGB).	26932432
Inflammation	Altered Intercellular Communication	Increasing evidence indicates that inflammation plays a vital role in tumorigenesis and progression.	26933932
Airway structure	Altered Intercellular Communication	Obstructive Sleep Apnoea Modulates Airway Inflammation and Remodelling in Severe Asthma.	26934051
Asthma	Altered Intercellular Communication	The role of OSA-related systemic and airway neutrophilic inflammation in asthma bronchial inflammation or remodelling has been rarely investigated.	26934051
Inflammation, Asthma, Osage language	Altered Intercellular Communication	The aim of this study was to compare hallmarks of inflammation in induced sputum and features of airway remodelling in bronchial biopsies from adult patients with severe asthma with and without OSA.	26934051
Critical Illness, Pneumonitis	Altered Intercellular Communication	These may suggest subtle pulmonary inflammation and support application of real time breath analysis for molecular monitoring in critically ill patients.	26934167
Inflammation, Nasopharyngeal carcinoma, Neoplasms	Altered Intercellular Communication	Primary tumor inflammation in gross tumor volume as a prognostic factor for nasopharyngeal carcinoma patients.	26934649
Pneumonitis	Altered Intercellular Communication	A double immunization of Fluzone(r) adjuvanted with CpG elicited the highest level of protection in young adult mice which was associated with increases in influenza specific IgG, elevated HAI titres, reduced viral titres and lung inflammation.	26934728
Communicable Diseases, Helicobacter pylori, Inflammation, Cognition Disorders	Altered Intercellular Communication	Helicobacter pylori (H. pylori) infection is associated with cognitive deficits in humans, an association potentially mediated or moderated by folate concentration or inflammation.	26935014
Inflammation, Liver Dysfunction, Arthritis, Pain of right shoulder joint, septic	Altered Intercellular Communication	A 43-year-old Japanese man presented with severe right shoulder pain and a body temperature of 38degC.Blood tests showed inflammation and liver dysfunction, although magnetic resonance imaging did not indicate septic shoulder arthritis.	26935440
Inflammation, Fibrosis Assessment, Fatty degeneration, Fatty Liver Disease	Altered Intercellular Communication	Simple steatosis (SS) was found in 18 subjects (54.5%), in another 15 (45.5%) signs of inflammation and fibrosis (NASH) were observed.	26935501
Inflammation	Altered Intercellular Communication	However, the function of group V phospholipase A2 in human M2 activation and T-helper-2 inflammation is ill-defined.	26936936
Transglutaminases, Nasal Polyps, Eosinophilic inflammation	Altered Intercellular Communication	We report that group V phospholipase A2 and transglutaminase-2 colocalized in macrophages of human nasal polyp tissue obtained from patients with T-helper-2 eosinophilic inflammation, and their coexpression positively correlated with the number of eosinophils in each tissue specimen.	26936936
Inflammation, Hypoxemia	Altered Intercellular Communication	Prolonged intradialytic hypoxemia was associated with laboratory indicators of inflammation, higher erythropoietin requirements, and higher all-cause hospitalization and mortality.	26936946
Inflammation, Arthritis	Altered Intercellular Communication	A secondary outcome was an assessment of knee function by Western Ontario and McMaster Universities Arthritis Index and Lequesne Index, knee ROM, and two inflammation markers (C-reactive protein and erythrocyte sedimentation rate).	26937646
Inflammation	Altered Intercellular Communication	Patterns of inflammation were defined according to the extent and distribution of inflammatory infiltrates within the artery.	26937893
Inflammation, Cerebrovascular accident, Mental disorders, Atherosclerosis	Altered Intercellular Communication	Neuropsychiatric diseases might enhance stroke development, possibly through inflammation and atherosclerosis.	26937918
Vitreous inflammatory cells	Altered Intercellular Communication	To compare anterior chamber and vitreous inflammation after intravitreal injection of ranibizumab or aflibercept.	26938579
Vitreous inflammatory cells, Uveitis	Altered Intercellular Communication	An examiner masked to medication graded anterior chamber and vitreous inflammation 1-2 and 5-7 days after injection according to the Standardization of Uveitis Nomenclature grading scheme.	26938579
Vasculitis	Altered Intercellular Communication	Biopsy enables early histological proof of a dermal vasculitic inflammation pattern and PCR analysis before subsequent serological controls and proofs.	26939104
Inflammatory Bowel Diseases	Altered Intercellular Communication	Vitamin D deficiency has been reported in patients with chronic inflammatory conditions, such as rheumatic and inflammatory bowel diseases (IBD).	26939587
Acute inflammation	Altered Intercellular Communication	Thus, we hypothesized that urinary sCD163 shed by crescent macrophages correlates with active glomerular inflammation.	26940094
Inflammation	Altered Intercellular Communication	Here we describe the crucial role of SIRT6 in aging and inflammation.	26940461
Inflammation	Altered Intercellular Communication	These findings confirm the key status of CR and disclose the critical role of SIRT6 on aging and inflammation.	26940461
Inflammation, Diabetic Retinopathy, GDC Disease Response Terminology	Altered Intercellular Communication	The role of inflammation in pathogenesis of diabetic retinopathy (DR) is getting increasingly recognized.	26940815
vascular inflammations	Altered Intercellular Communication	Macrophages are key players in atherogenesis, promoting vascular inflammation and arterial remodeling through cysteine cathepsin proteases.	26941255
HD Term Type, Inflammation, Bone Mineralization	Altered Intercellular Communication	Gelsolin is an actin-binding protein that can modulate inflammation, correlated inversely with hemodialysis (HD) mortality and involved in bone calcification homeostasis.	26941566
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Here, some markers of oxidative stress, systemic inflammation, and endothelial dysfunction are analysed in men younger and older than 45 years and in pre- and postmenopausal women.	26941571
Primary malignant neoplasm	Altered Intercellular Communication	Endothelial cell senescence is characterized by acquisition of senescence-associated secretory phenotype (SASP), able to promote inflammaging and cancer progression.	26943583
Inflammation, MS gene	Altered Intercellular Communication	YKL-40 is a CSF biomarker of intrathecal inflammation in secondary progressive multiple sclerosis.	26943959
Inflammation, Atherosclerosis	Altered Intercellular Communication	Hp-induced inflammation may be a risk factor for atherosclerosis in patients with VD.	26944122
Inflammation, Rupture, Plaque, Atherosclerotic	Altered Intercellular Communication	Progressive inflammation may contribute to the rupture of an atherosclerotic plaque.	26944327
Inflammation, Traumatic injury	Altered Intercellular Communication	Plasma galectin-3 concentrations have close relation to inflammation, trauma severity and clinical outcome, suggesting that galectin-3 should have the potential to be a good prognostic biomarker after STBI.	26944570
Inflammation, Atherosclerosis	Altered Intercellular Communication	BACKGROUND Regulated upon activation, normal T cells expressed and secreted (RANTES) is associated with inflammation and atherosclerosis.	26944934
Malignant Neoplasms	Altered Intercellular Communication	F-fluorodeoxyglucose positron emission tomography--an established modality for evaluating malignancies--exhibits increased uptake under inflammatory conditions.	26945389
Fever, CTCAE	Altered Intercellular Communication	No statistically significant difference in patients' characteristics, or in incidence of inflammation- or infection-related symptoms was seen between the two groups; nor any significant difference among those who developed fever and those who did not.	26945658
Pain Distress Question, Inflammation	Altered Intercellular Communication	DNA was genotyped for a priori selected genes involved with pain modulation (ADRB2, OPRM1, AVPR1A, GCH1, and KCNS1) and inflammation (IL1B, TNF/LTA, and IL6).	26945673
Inflammation, Helicobacter pylori, Carcinogenesis, S100A4 protein, human	Altered Intercellular Communication	Helicobacter pylori cause chronic inflammation favouring gastric carcinogenesis, and its eradication may prevent malignant transformation.	26945693
Inflammation, Visual Impairment, Atherosclerosis	Altered Intercellular Communication	Hearing and visual impairment were not associated with mortality after adjusting for subclinical atherosclerosis and inflammation.	26946102
Inflammation, Tooth Loss	Altered Intercellular Communication	We determined anthropometric measures, attachment loss, tooth loss and markers of systemic inflammation.	26946142
Inflammation, Tooth Loss	Altered Intercellular Communication	Systemic inflammation was associated with tooth loss in men but not in women even in women with wide girth.	26946142
Delirium	Altered Intercellular Communication	Accumulating evidences suggest that the pathophysiology of delirium results from multiple neurotransmitter system dysfunctions.	26946964
Delirium	Altered Intercellular Communication	Altogether, these results suggest that delirium rats induced by scopolamine may be correlated with an increased cerebral concentration of 5-HT and dopamine neurotransmitters system; the selective 5-HT(1A) antagoniszts can reverse the delirium symptoms at some extent through tendering PI3K/Akt/mammalian target of rapamycin complex 1 (mTOR) activation-induced NLRP3 activity and then reducing IL-1b release.	26946964
Muscle Spasticity, Cerebrovascular accident	Altered Intercellular Communication	However, 200-Hz TENS led to plasticity of synaptic transmission from the antagonist to spastic muscles in stroke survivors.	26949041
Inflammation, Basal cell hyperplasia	Altered Intercellular Communication	The biopsies illustrated significant eosinophilic inflammation, eosinophilic microabscesses and basal cell hyperplasia.	26949147
Inflammation, Virus Diseases, Impaired T cell function	Altered Intercellular Communication	Persistent viral infections are characterized by the simultaneous presence of chronic inflammation and T cell dysfunction.	26950238
Inflammation, Virus Diseases, Impaired T cell function	Altered Intercellular Communication	Targeted immunological interventions to disrupt the TNF-mediated link between chronic inflammation and T cell dysfunction might therefore lead to therapies to overcome persistent viral infection.	26950238
Inflammation	Altered Intercellular Communication	Metformin may play a role in reducing the FGF-21 levels in patients with T2DM, likely through the amelioration of glucose-lipid metabolism and inflammation.	26950284
Inflammatory Bowel Diseases	Altered Intercellular Communication	Inflammatory bowel disease (IBD) is a heterogeneous chronic inflammatory condition requiring significant healthcare expenditure.	26950309
Inflammation, Anemia, Chronic disease	Altered Intercellular Communication	Chronic inflammation can lead to anaemia of chronic disease due to the sequestration of iron caused by inflammatory cytokines and the protein hepcidin.	26950401
Inflammation, Arthritis	Altered Intercellular Communication	There is a link between joint and gut inflammation of unknown etiology in arthritis.	26950480
Refractory anemias, Arthritis	Altered Intercellular Communication	In separate studies, the accumulation of advanced glycation end-products has been associated with joint inflammation in RA.	26950480
Swollen Lymph Node, Inflammation	Altered Intercellular Communication	There were no signs of inflammation, no grip on the penile shaft, and no urethral discharge or enlargement of lymph nodes.	26951088
Ischemia, Inflammation, hearing impairment, Sleep Apnea, CTCAE, AKAP4 protein, human	Altered Intercellular Communication	Sleep apnea (SA) may promote hearing impairment (HI) through ischemia and inflammation of the cochlea.	26951413
Malignant neoplasm of urinary bladder, Inflammation, Carcinoma, Transitional Cell	Altered Intercellular Communication	Proteins involved in immunity, negative regulation of endopeptidase activity, and inflammation were more prevalent in UGS patients with bladder cancer, whereas proteins with roles in renal system process, sensory perception, and gas and oxygen transport were more abundant in subjects with urothelial carcinoma not associated with UGS.	26951512
Myocarditis	Altered Intercellular Communication	Cardiac Magnetic Resonance Reveals Signs of Subclinical Myocardial Inflammation in Asymptomatic HIV-Infected Patients.	26951603
Myocardial fibrosis, Myocarditis, Aortic Stiffness	Altered Intercellular Communication	CMR protocol allowed for the determination of cardiac function, myocardial inflammation, myocardial fibrosis, aortic stiffness, and pericardial fat volume.	26951603
Myocarditis	Altered Intercellular Communication	CMR parameters indicating myocardial inflammation were elevated in HIV-infected patients (native T1 relaxation times, 1128.3+-53.4 ms versus 1086.5+-54.5 ms; P=0.009; relative T2 signal intensity ratio, 1.6+-0.3 versus 1.4+-0.3; P=0.046; early gadolinium enhancement ratio, 3.1+-1.2 versus 2.1+-0.6; P=0.003).	26951603
Cardiovascular morbidity, Myocarditis, HIV Infections	Altered Intercellular Communication	Subclinical myocardial inflammation as detected by CMR may be a potential precursor of the increased cardiovascular morbidity and mortality observed in patients with chronic HIV infection.	26951603
Tissue damage, Inflammation	Altered Intercellular Communication	MST1R is predominantly expressed in the tissue-resident macrophages and is critical for innate immunity that protects organs from tissue damage and inflammation.	26951679
HD Term Type, Inflammation	Altered Intercellular Communication	Neutrophil-lymphocyte ratio (NLR), defined as the neutrophil count divided by lymphocyte count, is increasingly recognized as a marker of systemic inflammation, but its prognostic value in HD patients is unknown.	26951970
Ulcer, Vasculitis of large artery, Granulomatous inflammation	Altered Intercellular Communication	Histology of tissue biopsied from the ulcer indicated small vessel vasculitis and granulomatous inflammation.	26952849
vascular inflammations, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	Endothelial dysfunction, vascular inflammation and oxidative stress have been integrally linked to the pathogenesis of both type 2 diabetes and cardiovascular disease.	26954484
vascular inflammations, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	This study tested the hypothesis that AGE may improve endothelial function, oxidative stress, vascular inflammation and insulin resistance in high risk cardiovascular subjects with type 2 diabetes.	26954484
Depressed mood, Dyssomnias	Altered Intercellular Communication	Preexisting mild sleep disturbance as a vulnerability factor for inflammation-induced depressed mood: a human experimental study.	26954978
Inflammation	Altered Intercellular Communication	Systemic inflammation has been suggested as a potential mechanism of this association.	26954978
Dyssomnias, Depressed mood, Depression, CTCAE, Disease susceptibility	Altered Intercellular Communication	Inflammation-induced depressed mood was considerably more severe among females reporting mild sleep disturbance compared with those reporting no sleep disturbance, suggesting that even mild sleep disturbance may increase vulnerability for inflammation-induced depression in females.	26954978
Inflammation, Atherosclerosis	Altered Intercellular Communication	In silico pathway analysis on PM2.5-associated evmiRNAs identified several key CVD-related pathways including oxidative stress, inflammation, and atherosclerosis.	26956024
IgG4-Related Sclerosing Disease	Altered Intercellular Communication	IgG4-related disease (IgG4-RD) is a newly recognized fibro-inflammatory condition which disrupts the TJ associated epithelial barrier.	26956365
Refractory anemias, Inflammation	Altered Intercellular Communication	DcR3 and IL-23 may interact in a feedback loop that aggravates local inflammation in patients with RA.	26956410
Inflammation, Tuberculosis, Myelolipoma, Genus Histoplasma	Altered Intercellular Communication	There were total of 15 cases comprising of 5 tuberculosis, 5 Histoplasma, 2 acute inflammation, 2 granulomatous inflammation, and 1 myelolipoma.	26956774
septic	Altered Intercellular Communication	The C-reactive protein to albumin (CRP/Alb) ratio, a novel inflammation-based prognostic score, is associated with outcomes in septic patients.	26956901
Tissue damage, Inflammation	Altered Intercellular Communication	Neutrophil/lymphocyte ratio (NLR) is shown as a good prognostic marker for inflammation due to tissue damage in recent clinical trials.	26957274
Inflammation, Sarcopenia	Altered Intercellular Communication	Together, these effects contribute to limit the onset and the progression of sarcopenia, due to the major role played by inflammation in the pathophysiology of this disease.	26957282
Inflammation, Illness Behavior, Fatigue	Altered Intercellular Communication	Our analyses revealed that inflammation, neurotransmitter regulation, and energy metabolism are likely mechanisms associated with evening fatigue severity; that CTX may contribute to fatigue seen in oncology patients; and that the patterns of gene expression may be shared with other models of fatigue (e.g., physical exercise and pathogen-induced sickness behavior).	26957308
Inflammation, Illness Behavior, Fatigue	Altered Intercellular Communication	Our analyses revealed that inflammation, neurotransmitter regulation, and energy metabolism are likely mechanisms associated with evening fatigue severity; that CTX may contribute to fatigue seen in oncology patients; and that the patterns of gene expression may be shared with other models of fatigue (e.g., physical exercise and pathogen-induced sickness behavior).	26957308
Inflammation, Pain Distress Question	Altered Intercellular Communication	Experimental and clinical data suggest a close relationship between inflammation and pain perception.	26958751
Inflammation, Sepsis, BDI - Functional Impairment, Chronic pain, septic	Altered Intercellular Communication	Since sepsis is the most severe form of systemic inflammation, the primary objective was to evaluate chronic pain states and functional impairment of septic and nonseptic patients 6 months after discharge from ICU.	26958751
Sepsis, Hyperglycemia, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Admission hyperglycemia is associated with adverse outcome of sepsis irrespective of the presence or absence of preexisting diabetes by a mechanism unrelated to exaggerated inflammation or coagulation.	26958752
Ischemia, Inflammation, Diarrhea	Altered Intercellular Communication	It is hypothesized that the diarrhea might be due to ischemia in bowel mucosa or inflammation, but the exact underlying pathophysiological mechanism of the diarrhea is still unknown.	26959411
Inflammation, Colitis, Ischemic	Altered Intercellular Communication	The results showed endoscopically normal mucosa in the lower GI tract in seven patients without signs of ischemic colitis or inflammation.	26959411
Hepatocellular Adenoma	Altered Intercellular Communication	Hepatocellular adenomas may enlarge during pregnancy due to marked hormonal stimulation.	26959805
Inflammation, metabolic disturbance	Altered Intercellular Communication	This first GWAS on CUP provide preliminary evidence that germline genes relating to inflammation (LTA4H), metastatic promotion (TIAM1) in association with lipid metabolic disturbance (chromosome 11 cluster) may contribute to the risk of CUP.	26959888
Uveal melanoma, Inflammation, Edema	Altered Intercellular Communication	Hyperreflective spots increase in number with increasing central subfield thickness and could be considered as a new clinical biomarker of intraretinal inflammation in patients affected by macular edema secondary to irradiation for uveal melanoma.	26960014
glycation, vascular inflammations, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis	Altered Intercellular Communication	The receptor for advanced glycation end products (RAGE) plays a key role in the development of vascular inflammation and acceleration of atherosclerosis in type 2 diabetes.	26960737
methyldopa, Inflammation	Altered Intercellular Communication	Inflammation and immune-mediated processes are pivotal to the pathogenic progression of age-related macular degeneration (AMD).	26961257
methyldopa, Inflammatory abnormality of the eye	Altered Intercellular Communication	Although plasma levels of C-reactive protein (CRP) have been shown to be associated with an increased risk for AMD, the pathophysiological importance of the prototypical acute-phase reactant in the etiology of the disease is unknown, and data regarding the exact role of CRP in ocular inflammation are limited.	26961257
Inflammation, Abdominal Pain	Altered Intercellular Communication	The patient was discharged from the hospital on day 4 after the procedure, with no abdominal pain and no peritoneal signs of inflammation.	26961561
Inflammation, Respiratory Syncytial Virus Infections	Altered Intercellular Communication	The pathological features induced by RSV infection in HIS mice included peribronchiolar inflammation, neutrophil predominance in the bronchioalveolar lavage fluid, and enhanced airway mucus production.	26962219
Presenile dementia, Inflammation, Depression, CTCAE, Cardiovascular Diseases	Altered Intercellular Communication	Several studies have indicated that early inflammation, cardiovascular disease, and depression in patients were associated with a considerably increased risk of dementia.	26962833
Inflammation, Swelling	Altered Intercellular Communication	NSAIDs facilitate alleviating RA-associated chronic pain, inflammation, and swelling.	26962833
Alzheimers Disease", Periodontitis, Impaired cognition, Inflammation	Altered Intercellular Communication	Our data showed that periodontitis is associated with an increase in cognitive decline in Alzheimer's Disease, independent to baseline cognitive state, which may be mediated through effects on systemic inflammation.	26963387
Inflammation, Data types - Address	Altered Intercellular Communication	Inflammation in AD mice was alleviated by CLN treatment, including the accumulation of GFAP positive cells and the inflammatory cytokines.	26964005
Fibrosis Assessment, Calcinosis	Altered Intercellular Communication	Microscopic examination of the mass revealed a nodular focus of calcification and fibrosis with focal chronic inflammation of the atrial endocardium.	26964029
HSPG2 wt Allele, Inflammatory disease of mucous membrane	Altered Intercellular Communication	In patients receiving chemoradiotherapy showing severe oral mucosal inflammation outside the irradiation area or oral mucosal inflammation associated with skin lesions throughout the body, it is necessary to bear in mind the possibility of SJS.	26964396
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) patients exhibit chronic inflammation, both in the lung parenchyma and the airways, which is characterised by an increased infiltration of macrophages and T-lymphocytes, particularly CD8+ cells.	26965295
Inflammation	Altered Intercellular Communication	Resolvin E1 may play a key role in the resolution of acute inflammation when immunonutrition is supplemented with EPA.	26965712
Cholecystitis	Altered Intercellular Communication	The IR correlated significantly with the presence of acute gallbladder inflammation (p = 0.043).	26965715
Malnutrition	Altered Intercellular Communication	Dialysis Malnutrition and Malnutrition Inflammation Scores: screening tools for prediction of dialysis-related protein-energy wasting in Malaysia.	26965758
Plaque, Atherosclerotic	Altered Intercellular Communication	Apolipoprotein B-100 Antibody Interaction With Atherosclerotic Plaque Inflammation and Repair Processes.	26965851
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	This study investigated the association between p45 IgG autoantibodies and plaque inflammation in subjects with advanced cardiovascular disease.	26965851
Inflammation, Dental Plaque	Altered Intercellular Communication	In a subcohort of 195 subjects, endarterectomy samples were analyzed by immunohistochemistry and ELISA to determine plaque constituents and inflammation.	26965851
Dental Plaque, Plaque, Atherosclerotic	Altered Intercellular Communication	This study confirms previous experimental findings of anti-inflammatory properties of apolipoprotein B-100 p45 antibodies and provides the first clinical evidence of associations between p45 IgG autoantibody levels and atherosclerotic plaque inflammation, plaque repair as well as prevalent and incident cardiovascular events in carotid endarterectomy patients.	26965851
Malignant tumor of colon, Inflammation, Acute and chronic inflammation	Altered Intercellular Communication	Chronic intestinal inflammation is closely associated with colon cancer development and STAT3 seems to take center stage in bridging chronic inflammation to colon cancer progress.	26965998
Malignant tumor of colon	Altered Intercellular Communication	Consequently, this study proposes that inflammation-induced Jak-STAT3 signaling leads to colon cancer development through proteasomal degradation of DICER1 by ubiquitin ligase complex of CUL4A(DCAF1), which suggests a novel therapeutic opportunity for colon cancer.	26965998
Inflammation, Uveal Effusion Syndrome	Altered Intercellular Communication	Presence of uveal effusion and increased number of recurrences of inflammation are significant risk factors.	26967258
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Systemic inflammation may play a role in the link between particulate matter and cardiovascular disease.	26967353
Breast Carcinoma, Bipolar Disorder	Altered Intercellular Communication	Val66Met BDNF polymorphism as a vulnerability factor for inflammation-associated depressive symptoms in women with breast cancer.	26967918
Depression, CTCAE	Altered Intercellular Communication	Inflammation contributes to the development of depression in a subset of individuals, but risk factors that render certain individuals particularly vulnerable to inflammation-associated depression are undetermined.	26967918
Breast Carcinoma, Cognitive	Altered Intercellular Communication	The BDNF Met allele may be a risk factor for inflammation-associated cognitive depressive symptoms among breast cancer survivors.	26967918
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histologically, it showed a chronic inflammation and fibrosis.	26968047
Congenital cataract	Altered Intercellular Communication	An inflammatory condition may occur in eyes with congenital cataract.	26968721
Inflammation, Breast Carcinoma	Altered Intercellular Communication	In brief, our results suggested that resveratrol chemosensitizes doxorubicin in combination, through inhibiting breast cancer cells proliferation and invasion, and inducing apoptosis via suppression of chronic inflammation and autophagy.	26969377
Airway structure, Coughing, Acute upper respiratory infection	Altered Intercellular Communication	Eosinophilic airway inflammation is common in subacute cough following acute upper respiratory tract infection.	26969485
Coughing, Eosinophilic inflammation	Altered Intercellular Communication	Patients presenting with refractory postinfectious cough may respond to glucocorticosteroids but it is unclear whether airway eosinophilic inflammation exists in those patients.	26969485
Airway structure, Coughing, Acute upper respiratory infection	Altered Intercellular Communication	We aimed to determine the airway inflammation and causes of subacute cough following acute upper respiratory tract infection (AURTI).	26969485
Coughing, Airway structure	Altered Intercellular Communication	Subacute cough following AURTI can be attributed to different entities, eosinophilic airway inflammation is common.	26969485
Inflammation	Altered Intercellular Communication	The activity of the vaccine involves boosting the immune system through the stimulation of the inflammation in the bladder.	26969570
Inflammation, Endothelial dysfunction, Depression, CTCAE	Altered Intercellular Communication	Associations of low grade inflammation and endothelial dysfunction with depression - The Maastricht Study.	26970354
Inflammation, Depression, CTCAE, Endothelial dysfunction	Altered Intercellular Communication	The pathogenesis of depression may involve low-grade inflammation and endothelial dysfunction.	26970354
Inflammation, Endothelial dysfunction, Depressive disorder, Depressive Symptoms	Altered Intercellular Communication	We aimed to evaluate the independent associations of inflammation and endothelial dysfunction with depressive symptoms and depressive disorder, and the role of lifestyle factors in this association.	26970354
Inflammation, Endothelial dysfunction, Depressive disorder, Depressive Symptoms	Altered Intercellular Communication	Biomarkers of inflammation (hsCRP, TNF-a, SAA, sICAM-1) and endothelial dysfunction (sICAM-1, sE-Selectin) were univariately associated with depressive symptoms and depressive disorder.	26970354
Inflammation, Endothelial dysfunction, Depressive disorder, Cardiovascular Diseases	Altered Intercellular Communication	The sum scores of inflammation and endothelial dysfunction were associated with depressive disorder after adjustment for age, sex, type 2 diabetes, kidney function and prior cardiovascular disease (OR 1.54, p=0.001 and 1.40, p=0.006).	26970354
Inflammation, Endothelial dysfunction, Depressive Symptoms	Altered Intercellular Communication	The sum score of inflammation was also independently associated with depressive symptoms, while the sum score of endothelial dysfunction was not.	26970354
Inflammation, Endothelial dysfunction, Depressive disorder	Altered Intercellular Communication	Inflammation and endothelial dysfunction are both associated with depressive disorder, independent of lifestyle factors.	26970354
Inflammation, Endothelial dysfunction, Depression, CTCAE	Altered Intercellular Communication	Our results might suggest that inflammation and endothelial dysfunction are involved in depression.	26970354
ARCN1 gene, Airway structure, mucus secretion, Chronic Obstructive Airway Disease, Lung diseases	Altered Intercellular Communication	Chronic Obstructive Pulmonary Disease (COPD) is a chronic and progressive lung disease characterized by irreversible airflow obstruction, airway inflammation, oxidative stress and, often, mucus hypersecretion.	26970503
Cytomegalovirus Infections, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Cytomegalovirus Infection in Ulcerative Colitis is Related to Severe Inflammation and a High Count of Cytomegalovirus-positive Cells in Biopsy Is a Risk Factor for Colectomy.	26971053
Inflammation	Altered Intercellular Communication	The course and severity of the disease were analysed, with inflammation graded histologically across the range 0-3.	26971053
Inflammation	Altered Intercellular Communication	The CMV IHC-positive patients had lower haemoglobin [median 11.0g/dl vs 12.0; p = 0.028] and albumin [median 29.5g/l vs 33.1; p = 0.038] levels and more intense histological inflammation [p = 0.020] compared with CMV IHC-negative patients.	26971053
Cytomegalovirus Infections, Inflammation	Altered Intercellular Communication	CMV infection was related to more severe inflammation.	26971053
Inflammation, Fibrosis Assessment, Disease	Altered Intercellular Communication	These active, terminally differentiated, cytokine-secreting effector CD4(+) T cells are now linked to a human disease characterized by chronic inflammation and fibrosis.	26971690
Granulomatous inflammation, Tuberculosis, Pulmonary	Altered Intercellular Communication	An immunosuppressive condition might inhibit air-space pneumonia to become granulomatous inflammation as an initial stage of pulmonary tuberculosis.	26972247
Inflammation, Swelling, Bulla, ACTH Deficiency, Isolated	Altered Intercellular Communication	Typically IAD presents as inflammation of the skin surface characterised by redness, and in extreme cases, swelling and blister formation.	26972998
Coughing	Altered Intercellular Communication	Objective Cough Frequency, Airway Inflammation, and Disease Control in Asthma.	26973014
Airway structure, Coughing, Bronchial Hyperreactivity	Altered Intercellular Communication	Asthma control is thought to be determined by the degree of airway inflammation and hyperresponsiveness but how these factors relate to cough frequency is unclear.	26973014
Coughing, Asthma, Airway structure	Altered Intercellular Communication	The goal of this study was to investigate the relationships between objective cough frequency, disease control, airflow obstruction, and airway inflammation in asthma.	26973014
Coughing, Symptoms, Asthma, Airway structure	Altered Intercellular Communication	Ambulatory cough frequency monitoring provides an objective assessment of asthma symptoms that correlates with standard measures of asthma control but not airflow obstruction or airway inflammation.	26973014
Inflammation, Valve Device, Abnormal degeneration	Altered Intercellular Communication	The etiologic relation of SS to the valve lesions is not clear pathologically in this case, however, chronic inflammation related to immunologic reactions in SS could have some effect on exacerbation for degeneration of the valve tissue.	26973276
Inflammation	Altered Intercellular Communication	Platelet-to-lymphocyte ratio (PLR) was proposed as a novel indirect marker of inflammation.	26974393
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Histopathologic findings were chronic mucosal inflammation (87.3%), ulceration (74.5%), lymphocytic aggregation (69.1%), and granulomatous fusion (58.2%).	26974755
Inflammation, Hepatobiliary Disorder, Malnutrition	Altered Intercellular Communication	Predictors of mortality included the following: functional status (odds ratio [OR] = 2.87), liver disease (OR = 3.61), malnutrition (OR = 1.43), age greater than 65 years (OR = 2.39), American Society of Anesthesiologists 4 or higher (OR = 2.90), systemic inflammation (OR = 1.99), and contamination (OR = 2.15).	26975662
Communicable Diseases, Inflammation	Altered Intercellular Communication	These data suggest roles for tryptophan metabolism, infectious burden, activation of host defense, and detoxification through CYP1A-mediated pathways in mechanisms related to elevated inflammation, whereas CYP-mediated o-oxidation and PPAR-a activation may be related to decreased inflammation in older adults.	26975982
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation has been reported to play an important role in cancer progression, and several inflammatory markers, such as the neutrophil to lymphocyte ratio (NLR) and modified Glasgow prognostic score (mGPS), have been reported to be prognostic markers.	26976989
Chronic Obstructive Airway Disease	Altered Intercellular Communication	Controlled Mechanical Ventilation Attenuates the Systemic Inflammation of Severe Chronic Obstructive Pulmonary Disease Exacerbations.	26977971
Eosinophilic inflammation	Altered Intercellular Communication	The airway eosinophilic inflammation markers (FeNO more than 25 ppb and eosinophil counts of more than 150 cells/u) were elevated in 63% of the patients.	26978414
Eosinophilic inflammation	Altered Intercellular Communication	Traditional treatment is not always effective, as many patients, despite their treatment, have uncontrolled SA and continuously increased markers of airways eosinophilic inflammation.	26978414
Cessation of life, Inflammation	Altered Intercellular Communication	Despite complex treatment inflammation progressed in 5 of 8 patients followed by death.	26978620
Inflammation, Community	Altered Intercellular Communication	Psychological Resources Are Independently Associated with Markers of Inflammation in a Middle-Aged Community Sample.	26979423
Inflammation, Granuloma	Altered Intercellular Communication	High airway-centered FF score was associated with airway-centered acute inflammation (P=.028) and peribronchiolar granulomas (P=.042).	26980038
Metabolic Syndrome X	Altered Intercellular Communication	Intracellular metabolism of glucocorticoid hormones plays an important role in the pathogenesis of metabolic syndrome and regulates, among many physiological processes, collagen metabolism in skin.	26980090
Inflammation	Altered Intercellular Communication	The inflammatory involvement of vital organs may represent a dangerous and life-threatening situation: in particular, the inflammation of the myocardial tissue of the heart may lead to severe consequences since the clinical history of the disease may be completely asymptomatic, any clinical sign may be lacking, thus preventing correct diagnosis and treatment.	26980245
Inflammation	Altered Intercellular Communication	Patients with AFRS experienced a more-prolonged QoL benefit from surgical and targeted medical intervention compared with those with CRSsNP, which may reflect the severity of inflammation that they presented with compared with other CRS subtypes.	26980383
Smoking, Diabetes Mellitus	Altered Intercellular Communication	Smoking, diabetes mellitus and inflammatory conditions did not influence the results.	26980433
Inflammation	Altered Intercellular Communication	Our data suggest that the immune cell composition of the synovium and the IFP is similar, and includes activated cells that could contribute to inflammation through secretion of proinflammatory cytokines.	26980579
Inflammation, Pathology, Atherosclerosis	Altered Intercellular Communication	Endocan is a marker for vascular pathologies and an important mediator of angiogenesis, strongly associated with inflammation, vascular endothelial dysfunction, and atherosclerosis.	26980772
Inflammation, Neoplasms	Altered Intercellular Communication	However, IDO expression associated with poor survival in the sub-groups with primary tumor stage T2-T4 and in the sub-group with strong inflammation in tumors' invasive front.	26982018
Refractory anemias, Inflammation, Pain Distress Question	Altered Intercellular Communication	Previous studies have suggested a link between inflammation and central sensitization of pain in patients with RA.	26983452
Airway structure, Nephrotic Syndrome, Hypertension, CTCAE	Altered Intercellular Communication	We herein report the case of an 18-year-old boy who developed nephrotic syndrome and hypertension after upper airway inflammation.	26984084
Inflammation, Chronic disease	Altered Intercellular Communication	Diets rich in fruits and vegetables (FV), which contain (poly)phenols, protect against age-related inflammation and chronic diseases.	26984113
Inflammation	Altered Intercellular Communication	These results suggest that (poly)phenols derived from onions, turmeric, red grapes, green tea and acai berries may help reduce the release of pro-inflammatory mediators in people at risk of chronic inflammation.	26984113
Data types - Address	Altered Intercellular Communication	Our findings provide evidence for a modulatory role of inflammation-induced Ab phagocytosis and degradation by newly recruited peripheral immune cells in the pathophysiology of AD.	26984535
Inflammation, Primary malignant neoplasm, Diabetes Mellitus, Heart Diseases, Lung diseases	Altered Intercellular Communication	Protein S-glutathionylation, the formation of a mixed disulfide between glutathione and protein thiols, is an oxidative modification that has emerged as a new signaling paradigm, potentially linking oxidative stress to chronic inflammation associated with heart disease, diabetes, cancer, lung disease, and aging.	26984580
Inflammation, Fibrosis Assessment, Hypertrophy	Altered Intercellular Communication	However, transforming growth factor b and bone morphogenetic protein receptor II signaling, and hypertrophy, apoptosis, fibrosis, capillary density, inflammation, and cardiac metabolism, as well, were similar between mutation carriers and noncarriers.	26984938
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Polycystic Ovary Syndrome	Altered Intercellular Communication	Soluble CD163, which is identified as a marker of inflammation and type II diabetes, is elevated in polycystic ovary syndrome.	26985764
Inflammation, Impaired cognition, Immune System Diseases, HIV Infections	Altered Intercellular Communication	Microbial translocation from the gut is associated with immune dysfunction, persistent inflammation, and likely plays a role in the pathogenesis of neurocognitive dysfunction during HIV infection.	26986173
Inflammation, MUCOPURULENT CERVICITIS, Infertility, Prostate Cancer Outcomes Study, Endometriosis, Polycystic Ovary Syndrome	Altered Intercellular Communication	Our data showed that genital C. trachomatis infection was associated with infertility issues, inflammation in the reproductive tract (mucopurulent cervicitis or endometriosis), irregular menstrual cycles and polycystic ovarian syndrome (PCOS).	26987367
Cerebral Angiitis, Inflammation, Ischemic stroke, Structure of intracranial artery	Altered Intercellular Communication	In patients with ischemic stroke of unknown cause cerebral vasculitis is a rare but relevant differential diagnosis, especially when signs of intracranial artery stenosis are found and laboratory findings show systemic inflammation.	26988083
Giant Cell Arteritis, Arteritis	Altered Intercellular Communication	Temporal artery biopsy confirmed the suspected diagnosis of a giant cell arteritis and dedicated vessel wall MRI performed later supported the suspected intracranial large artery inflammation.	26988083
Inflammation	Altered Intercellular Communication	Inflammation has been suggested to play a vital role in the pathogenesis.	26988292
allergic inflammation, Craniosynostosis, Chronic sinusitis	Altered Intercellular Communication	Interleukin (IL)-9 and IL-17C have been known to play a role in allergic inflammation, yet, their roles in chronic rhinosinusitis (CRS) are not well defined.	26989880
Carcinoma, Tuberculosis, Xanthogranulomatous cholecystitis, Acute suppurative inflammation, Adenocarcinoma	Altered Intercellular Communication	The lesions diagnosed on FNA cytology included carcinoma (predominantly adenocarcinoma), xanthogranulomatous cholecystitis (XGC), acute suppurative inflammation and tuberculosis.	26990137
Granulomatous inflammation, Fibrosis Assessment, Granuloma, Necrosis	Altered Intercellular Communication	A skin biopsy specimen showed dermal fibrosis and patchy granulomatous inflammation in the upper-to-mid dermis that was associated with a perivascular, lymphohistiocytic infiltrate along with granulomas and necrosis in the subcutaneous fat.	26990341
Communicable Diseases, Inflammation, Enterobius vermicularis, Acute appendicitis NOS (disorder)	Altered Intercellular Communication	vermicularis in acute appendicitis has previously been questioned, with some studies identifying infection as a precursor for inflammation of the appendix, with others refuting such a link.	26990375
Inflammation, Infestation	Altered Intercellular Communication	Appendices were categorized by degree of inflammation and infestation with E .	26990375
Inflammation, Enterobius vermicularis	Altered Intercellular Communication	vermicularis did not have concurrent acute inflammation of the appendix on histological examination.	26990375
Appendicular colic, Inflammation, Infestation, Acute appendicitis NOS (disorder)	Altered Intercellular Communication	The question remains as to whether infestation is protective of inflammation or whether infestation causes appendiceal colic and subsequent appendicectomy of a non-inflamed appendix, thereby protective of the morbidity of acute appendicitis.	26990375
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Additionally, CK18 showed a significant correlation with the presence and the degree of hepatic fibrosis (p = 0.003) and inflammation (p<0.001) in liver histology.	26990427
Polyomavirus, Renal tubular disorder, Interstitial inflammation, Tubulitis Assessment	Altered Intercellular Communication	Polyomavirus nephropathy is characterized histopathologically by evidence of viral replication and acute tubular injury with interstitial inflammation, tubulitis, and intranuclear inclusions.	26992480
Inflammation, Perfusion (biological), Vascular occlusion, Amniotic Fluid	Altered Intercellular Communication	Placentas were analyzed for gross and histologic variables including maternal malperfusion, amniotic fluid infection sequence, chronic inflammation, and fetal vascular obstruction.	26992676
MS gene, Inflammation, Atrophic retina, Optic Nerve	Altered Intercellular Communication	Retinal atrophy in multiple sclerosis (MS) is secondary to optic nerve focal inflammation and to injury of the posterior visual pathway.	26993116
Inflammation, Microvascular Angina	Altered Intercellular Communication	Sex differences in the impact of CYP2C19 polymorphisms and low-grade inflammation on coronary microvascular disorder.	26993229
Inflammation, Microvascular Angina	Altered Intercellular Communication	We examined sex differences in the impact of the CYP2C19 genotype and low-grade inflammation on coronary microvascular disorder (CMVD).	26993229
Inflammation	Altered Intercellular Communication	CYP2C19 PM genotype may be a new candidate risk factor for CMVD via inflammation exclusively in the female population.	26993229
Inflammation, Prostate carcinoma	Altered Intercellular Communication	It remains to be established whether the link between inflammation and BPH progression supported by our findings reflects a progressive failure of the immune system leading to decreased immune surveillance and development of prostate cancer.	26993768
Inflammation, Pain Distress Question	Altered Intercellular Communication	While a myriad of chemical factors in the cytokine network stimulate local joint inflammation and pain, Interleukin 1 (IL-1) is widely recognized as a key offender and a potential therapeutic target.	26994310
Inflammation, Nerve Degeneration	Altered Intercellular Communication	These findings indicate an important role of ferritin light chains in neurodegeneration, that is linked to chronic inflammation processes and the associated activation of the microglia rich of L chains.	26994418
Colitis	Altered Intercellular Communication	All forms of colonic inflammation presented a dramatic decrease in apoptosis compared with healthy colon.	26995182
Gastrointestinal inflammation	Altered Intercellular Communication	Care has to be taken when analysing immune response in intestinal inflammation, as location-specific differences may be relevant.	26995182
Inflammation	Altered Intercellular Communication	Oligoclonal immunoglobulin G bands (OCBs) restricted to the cerebrospinal fluid indicate intrathecal inflammation.	26995358
Gastrointestinal inflammation	Altered Intercellular Communication	Fecal calprotectin (CPT) has been widely used in gastrointestinal inflammation, but comprehensive data in GI-GVHD are lacking.	26995779
Inflammation	Altered Intercellular Communication	Because hsCRP was related to FGF-21 and TNF-a was associated with leptin, these findings suggest a link between increased levels of these adipokines and hepatokines and chronic inflammation.	26996723
Inflammation, Migraine Disorders	Altered Intercellular Communication	Increased levels of C-reactive protein (CRP) have been considered as a marker in assessing neurogenic inflammation of migraine patients.	26996761
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	CXCL12 and its receptor CXCR7 may contribute to eosinophilic inflammation in patients with chronic sinusitis and nasal polyps.	26996902
Inflammation, Helicobacter pylori Positive	Altered Intercellular Communication	For Helicobacter pylori-positive patients, acute inflammation was more severe in the lesser curvature of the antrum compared with the greater curvature.	26997223
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	Inflammation is most severe in the lesser curvature of the antrum, which corresponds to a higher predilection to develop intestinal metaplasia at this site.	26997223
Pneumonitis	Altered Intercellular Communication	Chemokine CCL18, which has been linked to pulmonary inflammation, is an interesting candidate, but data have not been consistent.	26997242
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	The outcome was favorable with corticosteroids alone with regression of the clinical signs, disappearance of inflammation, and control of hypertension.	26997400
Inflammation, Malnutrition	Altered Intercellular Communication	Inflammation seems to affect prognosis more than malnutrition in this setting and may therefore guide clinicians' attitude towards therapeutic choices.	26999249
Inflammation, Traumatic injury	Altered Intercellular Communication	The relative size of the MPh populations differed between kidneys: the pDC population was bi-modally distributed being less than 2% of DC in two kidneys without severe injury and over 35% in the remaining three with low grade injury in the absence of morphological evidence of inflammation.	26999595
Inflammation	Altered Intercellular Communication	Systemic inflammation may be responsible for the rise in endocan levels following CPB.	26999704
Inflammation	Altered Intercellular Communication	Circulating levels of thioredoxin (Trx), a potent anti-oxidant that modulates inflammation, cell growth and apoptosis, are increased in various critical care conditions.	27000227
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Arterial Stiffness	Altered Intercellular Communication	We tested the hypothesis that in elderly COPD patients airflow limitation is associated with arterial stiffness and the relationship, if any, is related to endothelial function and systemic inflammation.	27000864
Inflammation, Thrombosis, Avian ventriculitis, Infarction, Cerebral Hemorrhage, Cerebritis	Altered Intercellular Communication	Observed pathological processes were inflammation of medium-large arteries in 30 brains (97 %), cerebral haemorrhage in 24 (77 %), cerebritis in 24 (77 %), thrombosis in 21 (68 %), infarction in 19 (61 %) and ventriculitis in 19 (of 28 cases, 68 %).	27001057
Vascular occlusion	Altered Intercellular Communication	Inflammation of medium-large arteries led to obstruction of the vascular lumen in 14 (of 31 cases, 45 %).	27001057
Infarction, vascular inflammations, Thrombosis	Altered Intercellular Communication	Vascular inflammation was associated with infarction and thrombosis of brain parenchymal vessels.	27001057
Airway structure	Altered Intercellular Communication	Asthma is a complex disease with heterogeneous features of airway inflammation and remodeling.	27001157
Airway structure, Hypertrophy	Altered Intercellular Communication	ASM enlargement occurred independently of features of airway inflammation and remodeling, whereas it was associated with PAR-2 overexpression and higher alveolar tryptase (P <= .02) and KLK14 (P <= .03) levels.	27001157
Hemorrhage, Neoplasms, Necrosis, Neurilemmoma, Osteogenesis, Intravascular papillary endothelial hyperplasia, Adrenal Cortical Adenoma	Altered Intercellular Communication	The adrenocortical adenomas (size, 1-13 cm; 25%-95% hemorrhage) showed clear cell change in the neoplastic area (10%-80% of the tumor), 19 showed focal calcification (1 with ossification), 11 showed areas of papillary endothelial hyperplasia, 10 showed scattered lymphoplasmacytic inflammation, 6 showed benign cortical tissue extending beyond the adrenal capsule into soft tissue, 1 showed necrosis in the form of ghost cells, 2 showed lipomatous change, and 6 were associated with incidental benign lesions (1 cortical cyst, 1 schwannoma, and 4 myelolipomas).	27001431
Inflammation	Altered Intercellular Communication	Findings suggest that mediation pathways for the overall association between chronic inflammation and QoL may differ markedly across particular outcome constructs.	27001461
Disability, Inflammation, Pain Distress Question	Altered Intercellular Communication	Pain and disability linked to chronic inflammation appear to play a small but significant mediating role in the overall reduction in QoL observed among older adults with biomarker evidence of chronic inflammation.	27001461
Deficit, Acute lymphocytic leukemia	Altered Intercellular Communication	The findings suggest that survivors of ALL should receive counseling regarding lifestyle and undergo screening for hormonal deficits to minimize the risk of low BMD and frailty.	27001572
Pancreatitis	Altered Intercellular Communication	Duct obliteration can lead to recurrent episodes of pancreatic inflammation mimicking acute and chronic pancreatitis.	27001600
ARCN1 gene, Chronic Obstructive Airway Disease, Inflammatory disorder	Altered Intercellular Communication	Chronic Obstructive Pulmonary Disease (COPD) is a chronic inflammation disease of the respiratory tract.	27001650
Inflammation, Asthma	Altered Intercellular Communication	The study of gene-environment interactions enables us to further understand the pathogenesis of asthma and inflammation.	27001655
Delirium, Inflammation	Altered Intercellular Communication	Unadjusted and adjusted odds ratios (95% CI) of delirium for residents exposed to at least one inflammation antagonist medication were 0.53 (0.34, 0.81) and 0.60 (0.38, 0.92), respectively.	27001903
Inflammation, Vestibular Diseases	Altered Intercellular Communication	The inflammatory responses and possible resolution obstacles of inflammation participated in persistent vestibular function disorders after irradiation.	27002826
Inflammation, Heart failure	Altered Intercellular Communication	Relationships Among Cognitive Function and Cerebral Blood Flow, Oxidative Stress, and Inflammation in Older Heart Failure Patients.	27002943
Inflammation, Impaired cognition	Altered Intercellular Communication	We investigated the relative contributions of cerebral blood flow velocity (BFV), oxidative stress, and inflammation to HF-associated cognitive impairment.	27002943
Inflammation, Serous, Traumatic injury, Hereditary	Altered Intercellular Communication	No differences in tubal injury or inflammation were seen when comparing the sporadic serous cancer group and the control group or within the hereditary group.	27003156
Inflammation, Brain Injury, Chronic	Altered Intercellular Communication	This small study, no correlation with chronic tubal injury or inflammation was identified.	27003156
Inflammation, Calcinosis, Abnormal degeneration, Aortic valve disorder	Altered Intercellular Communication	Calcific aortic valve disease is associated with inflammation and calcification, thus the osteoprotegerin (OPG), receptor activator of nuclear factor kB (RANK) and its ligand (RANKL) system involved in osteoclastogenesis and inflammation may play a significant role in valve degeneration.	27003233
Inflammatory abnormality of the eye	Altered Intercellular Communication	In total, 32 patients with ocular inflammation were treated with adalimumab.	27003323
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Adalimumab was moderately effective in controlling inflammation in a group of highly pre-treated cases of ocular inflammatory disease.	27003323
Inflammation, Hypertensive (finding), Aneurysm	Altered Intercellular Communication	NLR as a marker of chronic low-grade inflammation may play a role in the pathogenesis of aneurysm of the ascending aorta in hypertensive patients.	27003944
Inflammation, Dysplasia, Squamous cell carcinoma, Parasitic Diseases, Pemphigus Vulgaris, Lichen Planus, Keratosis	Altered Intercellular Communication	Histologically Lichen Planus was the most common lesion (32.5%), followed by chronic nonspecific inflammation in (22.5%), keratosis without dysplasia (10%), keratosis with dysplasia (8.8%), Pemphigus vulgaris (7.5%), fungal infestation (5%) and Squamous cell carcinoma (3.8%).	27004341
Inflammation, Endothelium	Altered Intercellular Communication	In conclusion, among patients with low-grade systemic inflammation, an oral NC significantly improved cholesterol profile and attenuated the degree of systemic inflammation and endothelial injury.	27004462
Inflammation, Metabolic Diseases, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Type 2 diabetes mellitus (T2D) is a metabolic disease with inflammation as an important pathogenic background.	27007651
Inflammation, Coin lesion of lung	Altered Intercellular Communication	We examined Aspergillus-specific IgG levels in patients who met the following criteria: (i) chronic (duration of >3 months) pulmonary or systemic symptoms, (ii) radiological evidence of a progressive (over months or years) pulmonary lesion with surrounding inflammation, and (iii) no major discernible immunocompromising factors.	27008878
ARCN1 gene, Inflammation, Cardiovascular Diseases, Atherosclerosis, Pulmonary Emphysema, Arterial Stiffness, Cardiovascular system	Altered Intercellular Communication	In an independent cohort of 186 patients with COPD and 110 control subjects, pDES levels were higher in COPD patients with cardiovascular disease and correlated with arterial stiffness (p<0.05).In COPD, excess elastin degradation relates to cardiovascular comorbidities, atherosclerosis, arterial stiffness, systemic inflammation and mortality, but not to emphysema or emphysema progression.	27009168
Acute Coronary Syndrome, Observation Method - Coagulation, Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	The aim of this study was to determine whether markers of inflammation and coagulation are associated with short-term particulate matter exposure and predict major adverse cardiovascular events at 360 d in patients with acute coronary syndrome (ACS).	27009348
Inflammation, Scleritis, Necrotizing, Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Serum IL-22 levels from patients with active scleritis were correlated with type of scleritis (non-necrotizing and necrotizing), degree of inflammation (0-4+ :<=2+ and >2+), and associated systemic disease.	27009382
Inflammation, Scleritis	Altered Intercellular Communication	There was no statistical association with scleritis type, degree of inflammation, or associated systemic disease.	27009382
Inflammation, Laminar necrosis, Necrosis, Calcified (qualifier), Intimal proliferation	Altered Intercellular Communication	Histopathologic features evaluated were: the severity of inflammation and intimal hyperplasia, both graded on a semiquantitative scale (mild = 1, moderate = 2, severe = 3), the presence of intraluminal acute thrombosis, calcifications, giant cells, fibrinoid necrosis and laminar necrosis.	27009904
Nasal inflammation, Necrosis	Altered Intercellular Communication	Additionally, they often coexist with nasal inflammation and mucosal necrosis.	27010643
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	One of the factors that contribute to Alzheimer's disease (AD) is the DNA damage caused by oxidative stress and inflammation that occurs in nerve cells.	27010693
Inflammation, Liver carcinoma	Altered Intercellular Communication	Dynamic change of the systemic immune inflammation index predicts the prognosis of patients with hepatocellular carcinoma after curative resection.	27010778
Inflammation, Gout, Spondylarthritis, Rheumatoid Arthritis, Inflammatory disorder	Altered Intercellular Communication	In our study, we analyzed power Doppler signals in inflammatory joint diseases including gout, calcium pyrophosphate deposition disease, rheumatoid arthritis, spondyloarthritis and others and correlated power Doppler signals with synovial white blood count and with serologic markers of inflammation.	27010839
Inflammation, Parasitic Diseases, Septicemia, Boundary Shift Integral	Altered Intercellular Communication	An association between blood stream infections (BSI) and HTLV-1 seropositivity in Indigenous Australians might result from HTLV-1 mediated inflammation and parasite coinfections that provide portals of entry for bacteria.	27011343
Inflammation	Altered Intercellular Communication	We hypothesize that airway LXA4 levels increase to compensate bronchoconstriction and suppress acute inflammation, and that spontaneous bronchodilatation after EIB may be due to LXA4.	27012012
Cogan-Reese syndrome, Inflammation, Anemia	Altered Intercellular Communication	Anemia Due to Inflammation in an Anti-Coagulated Patient with Blue Rubber Bleb Nevus Syndrome.	27012056
Inflammation, Fever, CTCAE	Altered Intercellular Communication	At admission, the patient also presented fever and increased laboratory parameters of systemic inflammation (ferritin 308 mcg/L, C-reactive protein (CRP) 244 mg/L).	27012056
Inflammation, Anemia	Altered Intercellular Communication	Unexpectedly, chronic severe anemia due to systemic inflammation was diagnosed in an old anticoagulated patient with BRNBS.	27012056
Inflammation, Fever, CTCAE, Gastrointestinal Hemorrhage	Altered Intercellular Communication	Fever and inflammation disappeared without any acute gastrointestinal bleeding and improvement of hemoglobin levels at three-month follow up.	27012056
Inflammation, Anemia, Gastrointestinal Hemorrhage	Altered Intercellular Communication	Surprisingly, anemia was mainly caused by systemic inflammation instead of chronic gastrointestinal bleeding.	27012056
Inflammation, Heart failure, Depression, CTCAE	Altered Intercellular Communication	Depression and markers of inflammation as predictors of all-cause mortality in heart failure.	27013355
Inflammation, Heart failure	Altered Intercellular Communication	In patients with heart failure (HF) depressive symptoms have been associated with mortality, as well as biological risk factors, including inflammation, nitric oxide (NO) regulation, and oxidative stress.	27013355
Inflammation, Bipolar Disorder	Altered Intercellular Communication	We investigated the joint predictive value of depressive symptoms, inflammation and NO regulation on all-cause mortality in patients with HF, adjusted for covariates.	27013355
Inflammation, Bipolar Disorder	Altered Intercellular Communication	When combined, both depressive symptoms and markers of inflammation and NO regulation remained significantly associated with all-cause mortality.	27013355
Inflammation, Heart failure, Bipolar Disorder	Altered Intercellular Communication	Depressive symptoms and markers of inflammation and NO regulation are codominant risk factors for all-cause mortality in heart failure.	27013355
Inflammation	Altered Intercellular Communication	Our findings suggest that inflammation has the potential to influence expression of genes, and potentially intestinal proteins, important to drug disposition and response.	27013401
Inflammation, Hypoxia	Altered Intercellular Communication	Angiotensinogen expression is down regulated in human ileal CD, particularly in the presence of inflammation and current cigarette smoking, implicating the mesenteric vasculature and mucosal hypoxia as co-factors in ileal CD pathogenesis.	27014752
Inflammation, Atrial Fibrillation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation plays a role in increased incidence of AF in patients with chronic kidney disease (CKD); reactive oxygen species and inflammatory markers which are increased in patients with CKD were found to affect the proper functioning of the intracellular ion channels, connexions (transmembrane proteins found in intercellular gap junctions), and electrical homogeneity of the extracellular matrix which are essential for electrical stability and proper conduction of electrical impulses in the atrium.	27015175
Hepatitis	Altered Intercellular Communication	The serum BAFF levels were significantly stratified in each 2 liver inflammation stage.	27015216
Hepatitis	Altered Intercellular Communication	Similarly, the serum IP-10 levels were significantly stratified in each 2 liver inflammation stage.	27015216
Fibrosis Assessment, Hepatitis, Insemination, Artificial, Homologous	Altered Intercellular Communication	In patients without advanced fibrosis (F3 or more), the serum BAFF level significantly correlated with serum IP-10 level (rs = 0.658, P < 0.001), whereas in patients with advanced fibrosis, the serum BAFF level significantly correlated with serum IP-10 level (rs = 0.542, P < 0.001).In conclusion, both BAFF and IP-10 are useful for predicting the degree of liver inflammation activity in AIH.	27015216
Hepatitis, Insemination, Artificial, Homologous	Altered Intercellular Communication	BAFF and IP-10 may have the common clinical implication for liver inflammation activity for AIH patients.	27015216
Inflammation	Altered Intercellular Communication	PCSK9 in relation to coronary plaque inflammation: Results of the ATHEROREMO-IVUS study.	27015246
Inflammation, physiopathological	Altered Intercellular Communication	The receptor of AGEs (RAGE) has an essential contribution to cellular dysfunction driven by chronic inflammatory responses while TGF-b1 is critical in both dermal homeostasis and inflammation.	27015414
Psoriasis	Altered Intercellular Communication	Psoriasis Skin Inflammation-Induced microRNA-26b Targets NCEH1 in Underlying Subcutaneous Adipose Tissue.	27015452
Dermatitis	Altered Intercellular Communication	However, the mechanistic links between psoriatic skin inflammation and systemic comorbidities remain largely unknown.	27015452
Psoriasis	Altered Intercellular Communication	MicroRNAs (miRNAs) are recently discovered gene regulators that play important roles in psoriasis skin inflammation.	27015452
Dermatitis	Altered Intercellular Communication	We conclude that this miRNA may serve as a mechanistic link between psoriatic skin inflammation and its systemic comorbidities.	27015452
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	To summarize, the inflammatory cytokines and steroid hormones may reflect the degree of inflammation in betel nut-chewing males and the oral cancer subjects.	27016129
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	To summarize, the inflammatory cytokines and steroid hormones may reflect the degree of inflammation in betel nut-chewing males and the oral cancer subjects.	27016129
Granulomatous inflammation, Carcinoma	Altered Intercellular Communication	EBUS-TBNA provided a definitive diagnosis (predominantly carcinoma and granulomatous inflammation) in 71%.	27016425
Inflammation, Atherosclerosis	Altered Intercellular Communication	Peroxisome proliferator-activated receptor-g (PPARg), liver X receptor-a (LXRa), and PPARg co-activator-1a (PGC-1a) are nuclear factors that regulate lipid metabolism and inflammation implicated in atherosclerosis.	27016616
Aneurysm, Dissecting, Vasculitis	Altered Intercellular Communication	Although vessel wall inflammation is suspected as one of the causes of cerebral arterial dissection, there have been few reports regarding the application of HRMR-VWI to arterial dissection.	27017283
Inflammation, Hemorrhage, Disease	Altered Intercellular Communication	In markers of periodontal inflammation, bleeding on probing was correlated with disease activity score 28 (r = 0.128, p = 0.041), RA disease duration (r = 0.211, p = 0.001), erythrocyte sedimentation rate (ESR; r = 0.141, p = 0.023), anti-cyclic citrullinated peptide antibody (r = 0.183, p = 0.009), and anti-citrullinated a-enolase peptide-1 antibody (r = 0.143, p = 0.025).	27017391
Inflammation, Disease	Altered Intercellular Communication	Periodontal inflammation was correlated with RA disease duration, ESR, and anti-citrullinated protein antibodies.	27017391
Inflammation	Altered Intercellular Communication	Serum androgens and inflammation might not contribute to insulin resistance in these women.	27018331
Inflammation, Hyperplasia, Neoplasms	Altered Intercellular Communication	Microscopic findings showed that the tumor consisted of inflammation of a lymph node, lymphoid follicles with hyperplasia of germ center and granulomatous inflammation with giant cells, and there was no malignant finding.	27018406
Inflammation, Atherosclerosis	Altered Intercellular Communication	Self-reported experiences of discrimination and inflammation among men and women: The multi-ethnic study of atherosclerosis.	27018725
Overactive, physiopathological, diabetic	Altered Intercellular Communication	Urothelial Dysfunction and Chronic Inflammation in Diabetic Patients with Overactive Bladder.	27018971
Inflammation, diabetic, physiopathological, Overactive Bladder	Altered Intercellular Communication	To investigate urothelial dysfunction, suburothelial inflammation, and muscarinic receptor expression in diabetic patients with overactive bladder (OAB).	27018971
Inflammation, physiopathological	Altered Intercellular Communication	Urothelial dysfunction and chronic suburothelial inflammation may contribute to the pathogeneses of OAB.	27018971
Inflammation	Altered Intercellular Communication	However, DM does not aggravate the severity of urothelial inflammation in OAB patients.	27018971
Inflammation, Cholangitis	Altered Intercellular Communication	Liver sclerostin was associated with the severity of cholangitis (p = 0.02) and indirectly with the degree of lobular inflammation (p = 0.03).	27019303
ARCN1 gene, Airway structure	Altered Intercellular Communication	The airways of COPD patients are often colonized with bacteria leading to increased airway inflammation.	27019597
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	An investigation of vago-regulatory and health-behavior accounts for increased inflammation in posttraumatic stress disorder.	27020074
Post-Traumatic Stress Disorder, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Posttraumatic stress disorder (PTSD) has been linked to chronic inflammation, a condition that poses a risk for cardiovascular disease.	27020074
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	Attenuated vagal activity has been proposed as a potential mediator of PTSD and inflammation, although associated behavioral health risks-namely cigarette smoking and alcohol dependence-might also account for that link.	27020074
Post-Traumatic Stress Disorder, Inflammation, Tumor necrosis	Altered Intercellular Communication	Inflammation was quantified by fasting serum concentrations of C-reactive protein (CRP), tumor necrosis factor (TNF)-a, interleukin (IL)-10, and thymus- and activation-regulated chemokine (TARC)/CCL17 collected from 85 participants with PTSD and 82 without PTSD.	27020074
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	PTSD symptom severity was associated with increased inflammation (b=.18, p=.02).	27020074
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	Together, RSA, smoking status, and lifetime alcohol dependence accounted for 95% of the effect of PTSD symptom severity on inflammation.	27020074
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Since major depression is associated with inflammation, we examined whether GDF-15 levels are elevated in patients with late-life depression.	27020076
Inflammation, Seminoma	Altered Intercellular Communication	OCT4 staining increases the detection of lymphatic/vascular invasion in pure seminoma of the testis obscured by prominent lymphohistiocytic inflammation.	27020494
Inflammation, Neoplasms, Testis, Seminoma, Lymphovascular Invasion 1	Altered Intercellular Communication	Lymphatic/vascular invasion (LVI) is an important prognostic feature in pure seminoma of the testis, a tumour that may be associated with lymphohistiocytic inflammation (LHI).	27020494
Autoimmune Diseases, Dermatitis, Atopic, Nephritis, Interstitial, Autoimmune Thyroid Disease Pathway	Altered Intercellular Communication	This particular pattern has not been associated with systemic autoimmune rheumatic disorders (SARD) but has been associated with other inflammatory conditions such as interstitial nephritis, autoimmune thyroid disease and atopic eczema as well as being found in healthy individuals.	27020500
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	One-hundred and twenty-four KAs were characterized with respect to age of the lesions both clinically and histopathologically, in addition to phenotypic characteristics such as cellular atypia, infiltration, inflammation and fibrosis.	27020606
Sepsis, Inflammation, Heat-Shock Proteins 70, Aplastic	Altered Intercellular Communication	Neither radiochemotherapy, nor inflammation or sepsis during aplasia induced HSP70 release into the serum.	27020764
Pain Distress Question, Inflammation	Altered Intercellular Communication	An abrupt onset was a consistent feature, with pain, complete loss of function, and local evidence of inflammation.	27020953
Inflammation, Fever, CTCAE	Altered Intercellular Communication	A single patient had a fever and 6 patients had laboratory evidence of systemic inflammation.	27020953
Inflammation	Altered Intercellular Communication	However, the clinical roles of plaque-related vulnerability and inflammation remain unclear.	27021042
Inflammation, Dental Plaque	Altered Intercellular Communication	Plaque inflammation and neovascularization have both been shown as important characteristics in vulnerable plaque.	27021564
Inflammation, Cerebral Infarction, Dental Plaque	Altered Intercellular Communication	Acute cerebral infarction patients showed intense contrast enhancement and inflammation in carotid plaque, and different types of plaque had various degrees of enhancement, suggesting that contrast-enhanced ultrasound and hs-CRP might be used for plaque risk stratification.	27021564
Inflammation, Wheezing, Pulmonary Dysfunction	Altered Intercellular Communication	Airways inflammation may precede pulmonary dysfunction in wheezing individuals.	27021575
Degenerative polyarthritis	Altered Intercellular Communication	The lincRNA p50-associated cyclooxygenase 2-extragenic RNA (PACER) and 2 novel chondrocyte inflammation-associated lincRNAs (CILinc01 and CILinc02) were differentially expressed in both knee and hip OA cartilage compared to non-OA cartilage.	27023358
Degenerative polyarthritis, Degenerative disorder of cartilage	Altered Intercellular Communication	Differential expression of CILinc01 and CIinc02 in hip and knee OA cartilage, and their role in modulating cytokine production during the chondrocyte inflammatory response, suggest that they may play an important role in mediating inflammation-driven cartilage degeneration in OA.	27023358
Inflammation, Venous Thromboembolism	Altered Intercellular Communication	Increased inflammation as reflected by higher circulating IL-6 and increased homocysteine concentrations may represent mechanisms linking 25(OH)D deficiency to greater risks of CVD and perhaps venous thromboembolism.	27023449
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	We further showed histone deacetylase 4 (HDAC4) is a direct target of miR-365, which mediates mechanical stress and inflammation in OA pathogenesis.	27023516
Inflammation, Pneumonia, Interstitial, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	IPF is a form of chronic, progressive fibrosing interstitial pneumonia and has more scarring, less inflammation, and poorer prognosis than most other ILD forms.	27023695
Thrombus, Inflammation	Altered Intercellular Communication	Most of the cutaneous manifestations of APS have been found to be thrombotic on histopathology without evidence of perivascular inflammation.	27024977
Inflammation, Atherosclerosis, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	The arachidonate 5-lipoxygenase enzyme plays a crucial role in mediating inflammation to maintain homeostasis, yet certain allelic variants of the 5-lipoxygenase gene, ALOX5, may increase risk of atherosclerosis and coronary heart disease (CHD).	27025886
Inflammation, Endometriosis, Female Genital Diseases, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Endometriosis is a prevalent gynecologic disease associated with systemic chronic inflammation, heightened oxidative stress, and atherogenic lipid profile that may increase women's risk for coronary heart disease (CHD).	27025928
nervous system disorder	Altered Intercellular Communication	The present case illustrates a possible link between auto-inflammation and auto-antibody-mediated neurological diseases.	27026266
Adenocarcinoma	Altered Intercellular Communication	Many adenocarcinomas and inflammatory conditions exhibit increased expression of ADAMs, 'a disintegrin and metalloproteinases'.	27026568
Inflammation	Altered Intercellular Communication	This is important because older adults regularly experience acute increases in systemic inflammation that may predispose older adults to cardiovascular events through dysregulation of blood pressure.	27027865
Arterial Stiffness, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Ageing is characterized by chronic, low-grade inflammation that is related to endothelial dysfunction and arterial stiffness.	27027865
Inflammation, Cardiovascular Physiological Phenomena	Altered Intercellular Communication	Physical activity can protect older adults (OAs) from cardiovascular dysfunction and increased inflammation.	27027865
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Acute inflammation causes transient endothelial dysfunction and arterial stiffening in younger adults (YAs), but may not have the same effect in OAs.	27027865
Inflammation, Impaired	Altered Intercellular Communication	We hypothesized that acute inflammation would increase blood pressure (BP) and endothelial impairment to a greater extent in OAs versus YAs, but that physical activity would be protective.	27027865
Inflammation, FRONTOMETAPHYSEAL DYSPLASIA 1	Altered Intercellular Communication	We conclude that acute inflammation reduced FMD only in YAs and reduced BP only in OAs.	27027865
Cardiac complication, Inflammation Mediators	Altered Intercellular Communication	Clinicians should be aware that all OAs are vulnerable to inflammation-mediated reductions in BP and cardiovascular complications.	27027865
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Improvement of insulin resistance and inflammation is a basic strategy in the management of type 2 diabetes.	27028002
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	In conclusion, resistant dextrin supplementation can modulate inflammation and improve insulin resistance in women with type 2 diabetes.	27028002
Esophageal carcinoma	Altered Intercellular Communication	Chronic inflammation-associated genomic instability paves the way for human esophageal carcinogenesis.	27028857
Inflammation, Primary malignant neoplasm, Esophageal carcinoma	Altered Intercellular Communication	Chronic inflammation is associated with increased risk of cancer development, whereas the link between chronic inflammation and esophageal carcinogenesis is still obscure heretofore.	27028857
Inflammation, Squamous cell carcinoma of esophagus	Altered Intercellular Communication	Endoscopic esophageal biopsies from 109 individuals from Chaoshan littoral, a high-risk region for esophageal squamous cell carcinoma (ESCC), were examined to evaluate the association between chronic inflammation and histological severity, while additional 204 esophageal non-tumor samples from patients with ESCC were collected.	27028857
Inflammation	Altered Intercellular Communication	Significantly positive correlation was observed between degree of chronic inflammation and esophageal precursor lesions (rs = 0.37, P < 0.01).	27028857
Inflammation	Altered Intercellular Communication	Immunohistochemical analysis showed that oxidative DNA damage level was positively correlated with the degree of chronic inflammation (rs = 0.21, P < 0.05).	27028857
Inflammation, precancerous lesions	Altered Intercellular Communication	We found that the extent of DSBs was progressively increased with inflammation degree (P < 0.01) and the progression of precancerous lesions (P < 0.001).	27028857
Esophageal carcinoma	Altered Intercellular Communication	Collectively, these findings provide evidence linking chronic inflammation-associated genomic instability with esophageal carcinogenesis and suggest possibilities for early detection and intervention of esophageal carcinogenesis.	27028857
Inflammatory abnormality of the eye	Altered Intercellular Communication	Thus, we demonstrated that CNV lesions trigger a systemic immune response, augmenting local ocular inflammation via the infiltration of IL-17-producing gdT-cells, which are presumably recruited to the eye in a C5a-dependent manner.	27029558
Refractory anemias, Inflammation	Altered Intercellular Communication	Therefore, the precise cellular distribution of PDPN and it's relationships with inflammation was studied in RA treated with biologic disease-modifying anti-rheumatic drugs (DMARD) or conventional DMARDs (cDMARD).	27030253
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	PDPN+ cells were immunostained by NZ-1 mAb, and scored (3+; >50%/ area, 2+; 20%- 50%, 1+; 5%-20%, 0: <5%) in synovial tissues from RA treated with biologic DMARDs (BIO, n=20) or cDMARD (n=20) for comparison with osteoarthritis (OA, n=5), followed by cell grading of inflammation and cell-typing.	27030253
Refractory anemias, Arthritis, Joints	Altered Intercellular Communication	PDPN may have potential of a new marker of residual arthritis in local joints for inflammation-associated severe RA.	27030253
Intraocular inflammation	Altered Intercellular Communication	There were no signs of intraocular inflammation, or change in lens status or increase in intraocular pressure throughout the study.	27030277
Inflammation	Altered Intercellular Communication	Xanthogranulomatous inflammation, which is known to occur in several viscera, is rarely found to affect the pancreas.	27030447
Pneumonitis	Altered Intercellular Communication	Conversely, immunization with a formalin-inactivated RSV (FI-RSV) vaccine induced high levels of inflammatory chemokines and cytokines of the Th2- and Th17-mediated types of immune responses, as well as severe lung inflammation and histopathology.	27030590
Inflammation, Uterine Fibroids, Hamartoma, Granuloma	Altered Intercellular Communication	Seven (3.8%) cases had significant lesions, including leiomyoma (n=2), endobronchial tuberculosis (n=2), chronic inflammation (n=1), hamartoma (n=1) and benign granuloma (n=1).	27030677
Dental Plaque	Altered Intercellular Communication	Our results suggest the possible existence of a new mechanism of intercellular communication in the plaque milieu.	27031176
Viral myocarditis, Myocarditis, Erectile dysfunction	Altered Intercellular Communication	Based on studies pointing to a role for the proinflammatory cytokine interleukin-1 in myocardial inflammation and contractile dysfunction, we treated a patient with fulminant viral myocarditis with the interleukin-1 receptor blocking agent anakinra.	27031379
Heart failure, Myocarditis, Erectile dysfunction	Altered Intercellular Communication	Clinical and experimental evidence suggests that interleukin-1 blockade is effective against myocardial inflammation and contractile dysfunction, thus representing a promising candidate for the treatment of inflammatory heart failure.	27031379
Inflammation, Physiologic Intraocular Pressure	Altered Intercellular Communication	Graft and nongraft-associated complications such as graft detachment, graft failure, graft rejection, anterior chamber inflammation, and intraocular pressure decompensation did not differ significantly between first and fellow eyes (P > 0.05, respectively).	27032023
Inflammation, Impaired cognition	Altered Intercellular Communication	Inflammation, Oxidation, Caloric Expenditure and Cognitive Impairment in Brazilian Elderly Assisted at Primary Care.	27033057
Inflammation, Specimen Type - Fistula, Diverticulitis	Altered Intercellular Communication	The fistula was of a primary vascular enteric type and was accentuated by the inflammation arising from the diverticulitis.	27033287
Inflammation, Fasciitis, Myositis, CTCAE 5.0	Altered Intercellular Communication	CT scan revealed fasciitis and myositis of the right rectus abdominis muscle with subcutaneous inflammation involving the fasciae and muscle.	27033292
Inflammation, Arthritis	Altered Intercellular Communication	Specialised pro-resolving mediators of inflammation in inflammatory arthritis.	27033423
Inflammation, Arthritis	Altered Intercellular Communication	They promote resolution of inflammation and may contribute to the beneficial effects of n-3FA in patients with arthritis.	27033423
Pain Distress Question, Arthritis, Inflammation, SCAPULOPERONEAL MYOPATHY, X-LINKED DOMINANT	Altered Intercellular Communication	SPM are present in chronic knee effusions and although the levels are lower than in plasma, the association between synovial fluid RvE2 and reduced pain scores suggests that synthesis of SPM at the site of inflammation is a relevant mechanism by which n-3FA alleviate the symptoms of arthritis.	27033423
Gastrointestinal inflammation	Altered Intercellular Communication	Little is known about the mechanisms that cause persistent intestinal inflammation in these patients.	27033429
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Immunoglobulin G4-related disease (IgG4-RD) represents a group of disorders that share features of inflammation, plasma cell infiltrates, and fibrosis.	27033871
Cholangitis, Sclerosing, Inflammation, Cholestasis, Cicatrization	Altered Intercellular Communication	Sclerosing cholangitis is a disorder involving inflammation, scarring, and destruction of the bile ducts.	27033871
Cardiac sarcoidosis, Myocarditis, Atherosclerosis	Altered Intercellular Communication	Patients with cardiac sarcoidosis (CS) suffer from myocardial inflammation, but atherosclerosis is not infrequent in these patients.	27035112
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic airway inflammation and airway remodeling are the major pathophysiological characteristics of chronic obstructive pulmonary disease (COPD).	27035424
vascular inflammations, Thrombosis, Cardiovascular Diseases	Altered Intercellular Communication	The function of platelets have extended way beyond the horizon of haemostasis and thrombosis, and are recognised as active participants in vascular inflammation, as well as in prothrombotic complications of cardiovascular diseases.	27036108
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Visfatin is an adipocytokine involved in cellular metabolism, inflammation, and cancer.	27036136
Inflammation	Altered Intercellular Communication	Moreover, CD16-triggered cytokine production by CD56(dim) NK cells may contribute to systemic inflammation as seen in SP arthralgia and SP RA.	27036380
Inflammation, Atherosclerosis	Altered Intercellular Communication	Protein-Protein interaction analysis evidenced a network among differentially expressed proteins in which vitronectin seems to represent a potentially pivotal node among fibrinolysis, complement dependent immune responses and inflammation in accordance with a number of in vitro and in vivo evidences for a contributory role of these proteins to the development of diabetic atherosclerosis.	27037039
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Clinical and paraclinical criteria were used to blindly determine evidence for autoimmune inflammation in both groups.	27037230
Have Autoimmune or Inflammatory Condition, LGI1 protein, human	Altered Intercellular Communication	Evidence for autoimmune inflammation was present in 7 (28%) of the VGKC-positive patients lacking LGI1 and Caspr2, compared to 9 (18%) of the VGKC-negative controls (p = 0.38).	27037230
Encephalomyelitis, Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Evidence for autoimmune inflammation was mainly found in patients with limbic encephalitis/encephalomyelitis (57%), but not in other clinical phenotypes (5%, p < 0.01).	27037230
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	However, antibodies to Caspr2 could also be detected in patients with inconclusive low VGKC titer, while many VGKC-positive patients had no evidence for autoimmune inflammation.	27037230
Have Autoimmune or Inflammatory Condition, LGI1 protein, human	Altered Intercellular Communication	VGKC positivity in the absence of antibodies to LGI1 and Caspr2 is not a clear marker for autoimmune inflammation and seems not to contribute in clinical practice.	27037230
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	No cutoff value for the VGKC titer was appropriate to discriminate between patients with and without autoimmune inflammation.	27037230
Inflammation, Psoriasis, Inflammatory dermatosis	Altered Intercellular Communication	Psoriasis is a common inflammatory skin disease, and inflammation may affect suicidal behaviour.	27038335
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Histological examination of spinal biopsy samples revealed lesions of necrosis, granulomatous inflammation and septate hyphae with acute-angle branching.	27038797
Inflammation	Altered Intercellular Communication	Recent findings suggest that increased visceral fat deposition is a modifier of inflammation.	27038807
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	They are associated with adverse clinical conditions such as atherosclerosis, endothelial dysfunction, inflammation and abnormal blood pressure variability.	27039198
Communicable Diseases, Inflammation	Altered Intercellular Communication	It is difficult to make a distinction between inflammation and infection.	27039298
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Association between biomarkers of tissue inflammation and progression of osteoarthritis: evidence from the Rotterdam study cohort.	27039382
Gastrointestinal inflammation	Altered Intercellular Communication	Consumption of milk containing A1 b-casein was associated with increased gastrointestinal inflammation, worsening of PD3 symptoms, delayed transit, and decreased cognitive processing speed and accuracy.	27039383
Inflammatory abnormality of the eye	Altered Intercellular Communication	The ocular inflammation is usually temporary and resolves with topical ocular steroids.	27039491
Inflammation, Epithelial metaplasia	Altered Intercellular Communication	The histological features of AILI sought were lobule-based alveolar wall thickening (myxomatous or fibrous) with epithelial metaplasia and negligible inflammation.	27040641
Communicable Diseases, Inflammation, Infection	Altered Intercellular Communication	Different markers of inflammation and/or infection in joint fluid have been proposed for diagnosis of these infections.	27040804
Inflammation, Rheumatic Heart Disease	Altered Intercellular Communication	Pathohistological Evidence of Smoldering Inflammation in Rheumatic Heart Disease with Massive Left Atrial Calcification.	27041159
Adaptive Immunity, Liver damage, Chronic inflammation	Altered Intercellular Communication	This may be due to accumulated cellular damage, decreases in adaptive immunity, and chronic inflammation.	27042933
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	GDF-15, iron, and inflammation in early chronic kidney disease among elderly patients.	27043030
Inflammation, Electrocardiogram: myocardial infarction (finding), Dental Plaque	Altered Intercellular Communication	p38 Mitogen-activated protein kinase (MAPK)-stimulated inflammation is implicated in atherogenesis, plaque destabilization, and maladaptive processes in myocardial infarction (MI).	27043082
Chronic Lymphocytic Leukemia	Altered Intercellular Communication	Biopsies of these nodules did not reveal the usual Th2 milieu of chronic lymphocytic leukemia but instead exhibited a Th1-rich lymphocytic infiltrate with resultant neutrophil and granulomatous inflammation.	27043332
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Colonoscopy, performed on the 40th day after termination of drug therapy, revealed diffuse inflammation in the distal aspect of the colon, with histologic findings consistent with ulcerative colitis.	27043835
Inflammation, Asthma	Altered Intercellular Communication	Detailed analysis of sputum and systemic inflammation in asthma phenotypes: are paucigranulocytic asthmatics really non-inflammatory?	27044366
Inflammation, Asthma, Inflammatory disorder	Altered Intercellular Communication	This study demonstrates that a significant eosinophilic inflammation is present across all categories of asthma, and that paucigranulocytic asthma may be seen as a low grade inflammatory disease.	27044366
Inflammation	Altered Intercellular Communication	Lifetime very high LTPA is associated with increased lowgrade inflammation and may, therefore, exert an atherogenic effect.	27044376
Inflammation, Primary malignant neoplasm, Cardiovascular Diseases, Hepatobiliary Disorder, Obesity, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Obesity is a global health problem presenting serious risk of disease fuelled by chronic inflammation, including type 2 diabetes mellitus, cardiovascular disease, liver disease and cancer.	27046081
Inflammation	Altered Intercellular Communication	We propose that chemokine-mediated trafficking of pro-inflammatory cells to the omentum and liver contributes to local and subsequent systemic inflammation.	27046081
Inflammation, Primary malignant neoplasm, Gastroesophageal Junction Adenocarcinoma, Obesity	Altered Intercellular Communication	Oesophagogastric adenocarcinoma (OAC) is an exemplar model of obesity and inflammation driven cancer.	27046081
Inflammation, Leucocytic infiltrate, Omentum, Obesity, Obesity-Associated Insulin Resistance	Altered Intercellular Communication	These novel data suggest that chemokine receptor antagonism may have therapeutic potential to reduce inflammatory T cell infiltration to the omentum and liver and in doing so, may ameliorate pathological inflammation in obesity and obesity-associated cancer.	27046081
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Mechanisms driving persistent airway inflammation in chronic obstructive pulmonary disease (COPD) are incompletely understood.	27046438
ARCN1 gene, Airway structure	Altered Intercellular Communication	As secretory immunoglobulin A (SIgA) deficiency in small airways has been reported in COPD patients, we hypothesized that immunobarrier dysfunction resulting from reduced SIgA contributes to chronic airway inflammation and disease progression.	27046438
Inflammation	Altered Intercellular Communication	The pathologic report revealed chronic inflammation due to the presence of a foreign body.	27048126
Asthma	Altered Intercellular Communication	In children with asthma, web-based monitoring and inflammation-driven therapy may lead to improved asthma control and reduction in medications.	27048197
Inflammation	Altered Intercellular Communication	The inflammation in gastric mucosa was analyzed with histology.	27048452
Inflammation	Altered Intercellular Communication	The H. pylori-infected gastric mucosa had more severe inflammation than uninfected samples.	27048452
Inflammatory abnormality of the eye	Altered Intercellular Communication	Chronic recurrent or persisting ocular inflammation was present in 15 of 19 patients (78.9%).	27048999
Obesity	Altered Intercellular Communication	Its etiology is unknown but in analogy to central obesity, chronic low-level inflammation in adipose tissue has been suggested.	27049087
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic Obstructive Pulmonary Disease (COPD) is characterised by increased neutrophilic inflammation.	27049289
Inflammation, Cirrhotic	Altered Intercellular Communication	This study did not find indications for oxidative stress and low-grade inflammation in the small and large intestine of stable compensated cirrhotic patients.	27049494
Inflammation, Cholestasis	Altered Intercellular Communication	Ursodeoxycholic acid (UDCA) is the first choice medication for most cholestatic hepatopathies, due to its capability to counteract inflammation and bile-acid-induced liver damage, two common features in cholestasis.	27049500
Stomach Carcinoma	Altered Intercellular Communication	The interleukin-6 (IL-6)/JAK/STAT3 signaling pathway plays a central role in inflammation-mediated cancers, including gastric cancer (GCa).	27049718
Inflammation, Graft dysfunction, Hyperglycemia	Altered Intercellular Communication	Severe inflammation leads to increased graft immunogenicity and risk of graft dysfunction; while acute hyperglycemia aggravates the inflammatory response and increases the risk of morbidity and mortality.	27050068
Refractory anemias, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In active RA, myocardial T1 relaxation times are prolonged suggesting diffuse inflammation or fibrosis.	27050802
Inflammation	Altered Intercellular Communication	Local myocardial scars and inflammation, visible as LGE, are also common, as are impairments of LV systo-diastolic function.	27050802
Refractory anemias, Inflammation, Rheumatoid Arthritis, Disease	Altered Intercellular Communication	To investigate the presence of biomechanical abnormalities and ultrasound (US)-detected inflammation and damage in low disease or remission status rheumatoid arthritis (RA) patients with foot complaints.	27050868
Inflammation, Acute onset pain, Postsurgical Stage I	Altered Intercellular Communication	Poor acute pain control and inflammation are important risk factors for Persistent Postsurgical Pain (PPSP).	27051077
Inflammation, Atherosclerosis	Altered Intercellular Communication	Linking CD11b (+) Dendritic Cells and Natural Killer T Cells to Plaque Inflammation in Atherosclerosis.	27051078
Inflammation, Atherosclerosis	Altered Intercellular Communication	To investigate whether the dynamics of leukocyte (sub)populations could be predictive for plaque inflammation during atherosclerosis, we analyzed innate and adaptive immune cell distributions in blood, plaques, and lymphoid tissue reservoirs in apolipoprotein E-deficient (ApoE(-/-)) mice and in blood and plaques from patients undergoing endarterectomy.	27051078
Inflammation, Dental Plaque	Altered Intercellular Communication	Secondly, a strong inverse correlation was observed between CD11b(+) cDC or natural killer T (NKT) cells in blood and markers of inflammation in the plaque (including CD3, T-bet, CCR5, and CCR7).	27051078
Inflammation, Obesity	Altered Intercellular Communication	Obesity stimulates chronic inflammation in adipose tissue, which is associated with insulin resistance, although the underlying mechanism remains largely unknown.	27051864
Intradermal Route of Drug Administration, Inflammation, Anemia	Altered Intercellular Communication	Correction for inflammation based on CRP and AGP did not markedly change the overall prevalence of ID and ID anemia.	27052301
Inflammation, Diabetes Mellitus, Hepatic Complication	Altered Intercellular Communication	Intake of polyphenols and polyphenol-rich fruit extracts has been shown to reduce markers of inflammation, diabetes, and hepatic complications that result from the consumption of a high-fat (HF) diet.	27052533
Inflammation	Altered Intercellular Communication	However, training at high external load also increased anti-inflammatory IL-1ra in male participants, which might be beneficial in combating low-grade inflammation.	27052561
Inflammation, Colitis	Altered Intercellular Communication	Hematoxylin and eosin stained tissue sections from colonic biopsies were classified histologically as normal or colitis (active/inactive), and scored for the degree of inflammation present (0-3, inactive/absent to severe).	27053850
Inflammatory Bowel Diseases, Inflammation, Crohn Disease	Altered Intercellular Communication	Histologic inflammation was significantly higher in visually diseased mucosa from IBD patients (1.95 +- 0.25) than in normal-appearing mucosa from control patients (0.25 +- 0.08, P < 0.01) and from IBD patients (0.65 +- 0.36, P < 0.05) and correlated inversely with VDR expression in visually diseased colonic tissue from IBD patients (r = -0.44, P < 0.05) and from IBD patients with Crohn's disease (r = -0.69, P < 0.05), but not in normal-appearing colonic tissue from control patients or IBD patients.	27053850
Vitreous inflammatory cells	Altered Intercellular Communication	At baseline, anterior chamber and vitreous inflammation were present in 6 (50%) and 7 (58.3%) of the eyes.	27054359
Vitreous inflammatory cells	Altered Intercellular Communication	Besides reduction anterior chamber and vitreous inflammation, we observed a reduction of OCT values, from 330.4+-58.5 mm at the onset of the biological agent to 273+-50 mm at month 12 (p=0.06).	27054359
Ruptured behavior, Cyst, Inflammation, Pain Distress Question	Altered Intercellular Communication	If ruptured, an inflammatory response can occur in the area surrounding the cyst, which can also induce pain, while the locations around intracranial and intraspinal extensions have a higher risk of inflammation; therefore, a definitive diagnosis is important.	27054417
Inflammation, Hemorrhage, Solitary diverticulum of cecum, Perforation (observation)	Altered Intercellular Communication	Solitary cecum diverticulum is a benign formation, but it can be complicated with inflammation, perforation and bleeding.	27054646
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Systemic inflammation plays an important role in the pathogenesis of atrial fibrillation (AF).	27055157
Neoplasms, Necrosis	Altered Intercellular Communication	Inflammation of the liver occurs after treatment as a result of radiation doses from the ion beam, and the tumor reaches a state of necrosis.	27055451
Inflammation	Altered Intercellular Communication	This study shows for the first time that sphingolipids and particularly glucosylceramide are associated with and are possible inducers of plaque inflammation and instability, pointing to sphingolipid metabolic pathways as possible novel therapeutic targets.	27055903
Inflammation	Altered Intercellular Communication	High MBL may contribute to low cIMT, whereas the association of MBL with low-grade inflammation was nonlinear.	27055907
Inflammation, Metabolic Diseases, Data types - Address	Altered Intercellular Communication	FABP5 is a biomarker of adiposity-associated metabolic derangements that include AD thus underscoring the concomitant presence of inflammation.	27055964
ARCN1 gene, Inflammation, Hypoalbuminemia	Altered Intercellular Communication	We demonstrated that poor periodontal health was associated with hypoalbuminemia, suggesting poor nutritional status and inflammation in COPD.	27056058
Inflammation, Primary malignant neoplasm, Demographics Domain, Atherosclerosis, Diabetes Mellitus	Altered Intercellular Communication	Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor ss family and has been associated with inflammation, cancer, aging, diabetes mellitus (DM) and atherosclerosis.	27056183
Hyperglycemia, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	In patients with CAD undergoing PCI with stent implantation, GDF-15 is determined by advanced age, acute and chronic hyperglycemia, inflammation and CKD.	27056183
Anemia, Syndrome	Altered Intercellular Communication	Furthermore, low T3 syndrome is closely associated with both malnutrition-inflammation complex syndrome (MICS) and anemia.	27056188
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a nonreversible inflammatory condition of the lungs.	27056359
Hyperplasia, Parathyroid Adenoma, Hyperparathyroidism, Primary, Malignant Neoplasms	Altered Intercellular Communication	Primary hyperparathyroidism is a rare disease characterized by excessive secretion of parathyroid hormone from parathyroid adenoma, hyperplasia, or malignancy.	27056365
Chorioretinitis, Glaucoma, CTCAE	Altered Intercellular Communication	Rare causes of neovascular glaucoma are multiple and are due to VEGF synthesis associated with chorioretinal inflammations or degenerations.	27057253
Crohn Disease, Inflammatory disorder	Altered Intercellular Communication	Can Dynamic Contrast-Enhanced MRI (DCE-MRI) and Diffusion-Weighted MRI (DW-MRI) Evaluate Inflammation Disease: A Preliminary Study of Crohn's Disease.	27057860
Inflammation, Neoplasms	Altered Intercellular Communication	Systemic inflammation and immune response were associated with prognosis of tumors.	27057867
Mycobacterium Infections, Lymphoid hyperplasia, Inflammation, Carcinoma of lung	Altered Intercellular Communication	Lung cancer was diagnosed in 12 lesions, nontuberculous mycobacterial disease in 1 lesion, lymphoid hyperplasia in 1 lesion, and inflammation in 3 lesions.	27058710
Inflammation	Altered Intercellular Communication	It has been suggested that chronic inflammation may be involved in the pathogenesis of frailty.	27058767
Nerve palsy, Inflammation, Seizures, Neuroleptic Malignant Syndrome, Cerebral Hemorrhage, malignant syndrome nos, Meningoencephalitis	Altered Intercellular Communication	Of the 31 patients with altered sensorium, 15 (40%) had meningoencephalitis, three (8%) had seizures, two (5%) had cerebral haemorrhages, one (2%) had a presentation likened to neuroleptic malignant syndrome (NMS) and one (2%) had a 6th nerve palsy with inflammation of the right cavernous sinus.	27059055
Inflammation Mediators, Neuropathy	Altered Intercellular Communication	Many cases of CTP are thought to be associated with neuropathy and recent data suggest an inflammation-mediated process is more common among patients with CTP.	27059628
Refractory anemias, Inflammation	Altered Intercellular Communication	The differential citrullinated proteins identified in RA SFs suggested potential autoantigens were targeted for ACPAs response and might contribute to the induction and perpetuation of complement activation and joint inflammation in RA.	27060082
Inflammation	Altered Intercellular Communication	In the false-positive cases, the number of tumor-infiltrating inflammatory cells at the primary skin site was highest among the four groups, suggesting that inflammation contributed to the false-positive uptake of FDG.	27060693
Inflammation, Neutrophil Infiltration	Altered Intercellular Communication	Neutrophil elastase plays an important role in skin inflammation induced by neutrophil infiltration.	27060697
Fibrosis Assessment, Hepatic inflammation, Hypertension, CTCAE, Liver Cirrhosis	Altered Intercellular Communication	To investigate whether the combination of sCD163 as a hepatic inflammation marker and the fibrosis markers of the Enhanced Liver Fibrosis score (ELF) can predict portal hypertension in patients with cirrhosis.	27061098
Refractory anemias, Inflammation	Altered Intercellular Communication	Hence, impaired CBG-mediated delivery of endogenous cortisol may perpetuate chronic inflammation in RA.	27061835
Inflammation, Hemochromatosis	Altered Intercellular Communication	The associations were not explained by inflammation and haemochromatosis genotype was not associated with QT interval length.	27062493
Inflammation, Hemochromatosis	Altered Intercellular Communication	In conclusion, increased iron stores, independent of haemochromatosis genotype and inflammation, are associated with prolongation of the QTc interval in men.	27062493
Acute Kidney Injury, CTCAE, Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	Plasma Neutrophil Gelatinase Associated-Lipocalin (NGAL) is a promising biomarker for acute kidney injury (AKI) detection; however, it is also increased with inflammation and few studies have been conducted in non-Caucasian populations and/or in developing economies.	27062515
Inflammation, glycation, diabetic	Altered Intercellular Communication	Pioglitazone alleviates inflammation in diabetic mice fed a high-fat diet via inhibiting advanced glycation end-product-induced classical macrophage activation.	27062545
Inflammation, diabetic	Altered Intercellular Communication	Classically activated macrophages (M1) are associated with inflammation in diabetic patients.	27062545
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Inflammation is a known risk factor in diabetes.	27062545
Inflammation, glycation, diabetic	Altered Intercellular Communication	The present study tested the hypothesis that pioglitazone (PIO) alleviates inflammation in diabetic mice fed a high-fat diet by inhibiting advanced glycation end-product (AGE)-induced classical macrophage activation.	27062545
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Therefore, we conclude that PIO blocks classical activation of macrophages and attenuates inflammation in mouse models of diabetes.	27062545
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation plays a pivotal role in cancer development and progression.	27062567
Inflammation, Carcinogenesis	Altered Intercellular Communication	HMGB1 is an extracellular signalling molecule that plays a role both in inflammation and carcinogenesis.	27062570
ARCN1 gene, Respiratory physiology, Chronic Obstructive Airway Disease, Inflammation	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by progressive loss of lung function and local and systemic inflammation, in which CD8+ T-cells are believed to play a key role.	27064034
ARCN1 gene, Inflammation	Altered Intercellular Communication	Peripheral Tc17 cells are increased and more likely to convert to Tc17/IFN-g cells in COPD, suggesting that Tc17 cell plasticity may be involved in persistent inflammation of the disease.	27064034
Inflammation, Diabetic Foot, Ulcer	Altered Intercellular Communication	To verify the reliability and validity of FLIR ONE, a device connected to a smartphone, for the assessment of inflammation based on relative temperature increase compared with the thermography routinely used in pressure ulcer (PU) and diabetic foot assessment.	27064366
Inflammation, Diabetic Foot	Altered Intercellular Communication	This pilot study suggests that FLIR ONE can work as an alternative device for assessing subclinical inflammation in PUs and the diabetic foot in clinical settings.	27064366
Inflammation, Non-Small Cell Lung Carcinoma, Necrotizing	Altered Intercellular Communication	Does Every Necrotizing Granulomatous Inflammation Identified by NSCLC Resection Material Require Treatment?	27064420
Necrotizing granulomatous inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Patients who had NSCLC surgery between 2009 and 2013 were included and patient records were reviewed for the presence of necrotizing granulomatous inflammation (NGI) in resected specimens.	27064420
Granulomatosis, Granulomatous inflammation, Necrotizing vasculitis, Systemic Vasculitis	Altered Intercellular Communication	Granulomatosis with polyangiitis (GPA), extremely rare in children, is a disease characterized by granulomatous inflammation and necrotizing vasculitis that involves medium and small vessels.	27066798
RECIL MR, Sinusitis	Altered Intercellular Communication	MR in the last episode indicated bilateral sphenoid sinus inflammation adjacent to the left optical nerve.	27066798
Refractory anemias, Inflammation	Altered Intercellular Communication	RA and CVD both have inflammation as part of the underlying biology.	27067270
Refractory anemias, Inflammation	Altered Intercellular Communication	In RA, greater GlycA associated with disease activity (DAS-28; RDAS-28 = 0.5) and inflammation (RESR = 0.7, RhsCRP = 0.7, RIL-6 = 0.3: P < 0.05 for all); in BMI-matched controls, these inflammatory associations were absent or weaker (hsCRP), but GlycA was related to IL-18 (RhsCRP = 0.3, RIL-18 = 0.4: P < 0.05).	27067270
Celiac Disease, Malabsorption Syndrome, Atrophic	Altered Intercellular Communication	Coeliac disease (CD) is a gluten-induced autoimmune inflammation of small bowel villi, leading to atrophy and malabsorption.	27067921
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	(18)F-FDG PET/CT has a promising role in grading inflammation in patients with large arteries vasculitis.	27068039
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Future studies should focus on social and genetic determinants of inflammation and their association with CKD in this ethnicity.	27068267
Inflammation, Malignant Pleural Mesothelioma, 1-methyl-1-piperidinomethane sulfonate	Altered Intercellular Communication	Inflammation plays a role in malignant pleural mesothelioma (MPM) prognosis and symptoms.	27068290
Inflammation, Carcinogenesis, Ovarian Carcinoma	Altered Intercellular Communication	Our data suggest that TNF-a expression in ovarian carcinoma varies by histologic subtype and provides some support for the role of inflammation in ovarian carcinogenesis.	27068525
Barrett Esophagus, Acid reflux, "Barretts Adenocarcinoma	Altered Intercellular Communication	Barrett's esophagus (BE) caused by gastroesophageal reflux is a major risk factor of Barrett's esophageal adenocarcinoma (BEA), an inflammation-related cancer.	27069317
Tissue damage, Inflammation	Altered Intercellular Communication	Chronic inflammation and following tissue damage may activate progenitor cells under reactive oxygen/nitrogen species-rich environment.	27069317
Primary malignant neoplasm, Inflammation Mediators	Altered Intercellular Communication	Our results suggest that BE columnar epithelial cells with CD133 expression in apical surface undergo inflammation-mediated DNA damage, and mutated cells acquire the property of cancer stem cells with cytoplasmic CD133 expression.	27069317
Inflammation, Platelet aggregation test result	Altered Intercellular Communication	However, mediators of inflammation (C-reactive protein, Txnip) did not correlate significantly with LASp nor did extent of ADP-induced platelet aggregation or platelet NO response.	27069318
Inflammation, Platelet aggregation	Altered Intercellular Communication	These results suggest that the thrombogenic risk associated with LA stasis is independent of secondary effects on platelet aggregability or inflammation.	27069318
Intraocular inflammation, Uveitis	Altered Intercellular Communication	Uveitis reactivation was ascribed to clinically quiescent patients who developed reactivation of intraocular inflammation within 6 months.	27070110
Inflammation, Uveitis	Altered Intercellular Communication	A total of 606 consecutive patients with uveitis were screened for etiologies and classified according to the anatomic sites of inflammation.	27070829
Inflammation	Altered Intercellular Communication	However, little is known about the biomarker role of telomere length (TL) for predicting inflammation and glucose alterations.	27071798
Obesity	Altered Intercellular Communication	Relationship Between Measures of Adiposity, Arterial Inflammation, and Subsequent Cardiovascular Events.	27072302
Arteritis	Altered Intercellular Communication	VAT volume (r=0.290; P<0.001) and VAT/SAT ratio (r=0.208; P<0.001) were positively correlated with arterial inflammation.	27072302
Inflammation	Altered Intercellular Communication	The findings suggest that arterial inflammation may explain some of the CVD risk associated with adiposity.	27072302
Refractory anemias, Arthritis	Altered Intercellular Communication	Ultrasound-detected joint inflammation and B cell count: related variables for rituximab-treated RA patients?	27072348
Inflammation	Altered Intercellular Communication	The age-dependent increase in CSF-[KYNA] may reflect a compensatory response to age-related inflammation, which may be deficient in KATII-TT-carriers.	27072370
Inflammation	Altered Intercellular Communication	The lesion was biopsied in the outpatient setting and demonstrated ulceration with marked acute and chronic inflammation in addition to granulation tissue.	27072732
Inflammation, Apocrine sweat gland structure, Chronic disease	Altered Intercellular Communication	Fox-Fordyce disease (FFD) is a rare chronic disorder characterised by persistent inflammation because of the obstruction of apocrine sweat glands, which is a key factor of pathogenesis.	27072751
Inflammation, Stenosis of lacrimal punctum	Altered Intercellular Communication	Recent studies have highlighted inflammation in punctoplasty specimens in patients with punctal stenosis.	27073206
Cerebrovascular accident	Altered Intercellular Communication	Obstructive Sleep Apnea in Acute Stroke: A Role for Systemic Inflammation.	27073238
Inflammation, Osage language, Thrombophilia, Cerebrovascular accident	Altered Intercellular Communication	We prospectively evaluated clinical characteristics and laboratory markers of inflammation and coagulability associated with OSA severity during the acute post stroke period.	27073238
Inflammation, diabetic	Altered Intercellular Communication	Insulin Resistance in Relation to Lipids and Inflammation in Type-2 Diabetic Patients and Non-Diabetic People.	27073920
Airway structure, Asthma, Bronchial Hyperreactivity	Altered Intercellular Communication	Previous studies on association between level of asthma control, markers of airway inflammation and the degree of bronchial hyperresponsiveness (BHR) have yielded conflicting results.	27074221
Inflammation, Fatty degeneration	Altered Intercellular Communication	Serum miR-122 levels (calibrated relative to the median levels of patients) partly affected severity of steatosis, ballooning, lobular inflammation, and stage.	27074850
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	However, whereas VB-201 inhibited the development of fibrosis and, to some extent, liver inflammation, VB-703 significantly lessened both liver inflammation and fibrosis.	27074921
Inflammation, Blood Coagulation Disorders	Altered Intercellular Communication	Blood examination showed inflammation reaction and slight disseminated intravascular coagulopathy.	27075151
Inflammation, Acute appendicitis NOS (disorder)	Altered Intercellular Communication	Evaluation of mediators of oxidative stress and inflammation in patients with acute appendicitis.	27075266
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Plasma variation and reproducibility of oxidized LDL-cholesterol and low-grade inflammation biomarkers among participants of the Malmo Diet and Cancer cohort.	27075407
Inflammation, Hypertriglyceridemia, Obesity	Altered Intercellular Communication	The Association Between Obesity and Cognitive Function in Older Persons: How Much Is Mediated by Inflammation, Fasting Plasma Glucose, and Hypertriglyceridemia?	27075896
Inflammation, Hypertriglyceridemia, Obesity	Altered Intercellular Communication	There is a weak positive association between obesity and cognitive performance in older persons, which is partially antagonized by inflammation and elevated fasting plasma glucose, but not hypertriglyceridemia.	27075896
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Role of noninvasive biomarkers of intestinal inflammation in evaluation of patients with UC is not well understood.	27076259
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Although it is well-recognized that SJS/TEN is associated with severe ocular mucosal inflammation and cicatrizing, potentially blinding, sequelae, this association has not been described in relation to other SCARs.	27078005
Inflammatory abnormality of the eye	Altered Intercellular Communication	The ocular surface inflammation was addressed with intensive topical corticosteroid ointment.	27078005
Inflammatory disease of mucous membrane	Altered Intercellular Communication	The development of severe ocular surface mucosal inflammation and denudation with cicatrizing sequelae in a patient carrying a diagnosis of DRESS/DIHS has diagnostic and therapeutic implications for the ophthalmologist.	27078005
Parkinson Disease, Inflammation	Altered Intercellular Communication	The levels of IL-8 and TNF-a were significantly lower in serum of Parkinson's disease patients, which suggested that inflammatory factors might exert their effect and more specifically, inflammation might play crucial role in Parkinson's disease.	27078697
Inflammation, Atherosclerosis	Altered Intercellular Communication	Autophagy dysfunction in mouse atherosclerosis models has been associated with increased lipid accumulation, apoptosis and inflammation.	27079462
Granulomatous inflammation	Altered Intercellular Communication	These findings on LSFG and ICGA clearly demonstrated subclinical involvement as well as post-treatment improvement of choroidal circulation impairment due to granulomatous inflammation in eyes with the anterior recurrence of VKH disease.	27079805
Meningioma	Altered Intercellular Communication	Meningiomas can present during pregnancy as the result of hormonal as well as fluid changes.	27080233
Inflammation, Toxic effect, Communicable Diseases, Leukopenia, Anaphylactoid Reaction	Altered Intercellular Communication	Subjects will receive a 2- to 6-week course of anakinra by daily subcutaneous injection and will be assessed for resolution of inflammation and dose limiting toxicities (leukopenia, anaphylactoid reaction, or severe infection).	27080929
Middle Age, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	In middle-age group, a multivariate-forward logistic regression analysis showed that male sex (2.169 [1.029, 4.574], P = 0.042), inflammation (4.167 [2.043, 8.498], P < 0.001), cardiovascular disease (2.92 [1.019, 8.402], P = 0.046), serum creatinine level (0.639 [0.538, 0.758], P < 0.001), and cholesterol level (0.984 [0.975, 0.993], P = 0.001) were associated with serum albumin level <3.6 g/dL.	27082584
Inflammation, Arteriovenous fistula, Hepatitis C	Altered Intercellular Communication	Hepatitis C virus infection (1.911 [1.186, 3.077], P = 0.008), HDF (2.143 [1.298, 3.540], P = 0.003), inflammation (2.309 [1.549, 3.440], P < 0.001), use of arterio-venous fistula (0.518 [0.327, 0.820], P = 0.005), Kt/V (0.395 [0.193, 0.809], P = 0.011), nonanuria (0.542 [0.337, 0.870], P = 0.011), serum creatinine level (0.744 [0.669, 0.828], P < 0.001), and cholesterol level (0.993 [0.987, 0.998], P = 0.013) were associated with serum albumin level <4 g/dL.	27082584
Airway structure, ARCN1 gene, Asthma	Altered Intercellular Communication	Exhaled nitric oxide (eNO) has been documented as a marker of airway inflammation in asthma, but not in COPD.	27082615
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	We conclude that asthma with FAO may represent residual inflammation in the airways, while dynamic hyperinflation in COPD may retain NO in the distal airspace.	27082615
ARCN1 gene	Altered Intercellular Communication	In this study, we sought to differentiate an IL-1b-associated sputum signature from other inflammation-associated COPD phenotypes.	27083436
Inflammation	Altered Intercellular Communication	Sputum IL-1b levels showed no significant association (p > 0.05, spearman) with known markers of other major COPD inflammation phenotypes.	27083436
Tissue damage, Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	Tissue damage volume predicts organ dysfunction and inflammation after injury.	27083966
Multiple Organ Failure, Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	Multiply injured patients (MIPs) are at risk to develop multiple-organ failure (MOF) and prolonged systemic inflammation response syndrome (SIRS).	27083966
Inflammation, Squamous cell carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Squamous cell carcinomas are malignant tumours of epithelial origin that can appear on sites subjected to chronic inflammation after a period of several years.	27083971
Inflammation, Juvenile rheumatoid arthritis, Uveitis	Altered Intercellular Communication	To describe the clinical and visual outcomes of juvenile idiopathic arthritis (JIA)-associated uveitis in adults and to examine risk factors for ongoing inflammation in adulthood.	27084082
Cataract, Inflammation	Altered Intercellular Communication	The presence of posterior synechiae, hypotony, cataract at presentation, and a history of cataract surgery prior to presentation were predictive of ongoing inflammation in adulthood in univariate analysis.	27084082
Inflammation, Visual Impairment, Complication Aspects, Uveitis	Altered Intercellular Communication	JIA-associated uveitis may be associated with ongoing inflammation, ocular complications, and severe visual impairment in adulthood.	27084082
Inflammation, Peripheral demyelinating neuropathy, Edema	Altered Intercellular Communication	Sonography of peripheral nerves can depict alteration of nerve sizes that could reflect inflammation and edema in inflammatory and demyelinating neuropathies.	27084237
Arterial Stiffness, Inflammation, Metabolic Diseases	Altered Intercellular Communication	The mechanisms linking air pollution and cardio-metabolic disorders may be associated with the increased systemic inflammation and oxidative stress, reduced insulin sensitivity and elevated arterial stiffness and blood pressure.	27084335
Inflammation, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Acute myocarditis in its arrhythmic phenotype is probably characterized by a significant inflammation of conduction tissue.	27084370
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Oral lichen planus (OLP) is a common T-cell-dominated oral chronic inflammatory disease occurring in periods of remission, quiescence, activity with pronounced inflammation, and acute ulceration.	27084447
Inflammation	Altered Intercellular Communication	These findings suggest that inflammation may be important for understanding mortality disparities by socioeconomic status.	27085072
Inflammation, Perforation (observation), Peritonitis	Altered Intercellular Communication	In patients with perforation, absence of CT findings suggestive of surrounding inflammation or peritonitis would help in choosing non-surgical management.	27085213
Pancreatitis, Acute, Inflammation	Altered Intercellular Communication	In this study, we show that B10 cells can inhibit inflammation of severe acute pancreatitis (SAP).	27085321
Inflammation, Cardiac complication	Altered Intercellular Communication	Gender difference in obesity-associated cardiovascular complication could be derived from divergent chronic inflammation.	27086574
Inflammation	Altered Intercellular Communication	In conclusion, Innate signals were differentially expressed in male and female adipose tissues, suggesting that the depot- and gender-specific signals could be related to gender difference in chronic inflammation.	27086574
Inflammation, Structure of right colic lymph node, Gallbladder	Altered Intercellular Communication	Eosinophilic inflammation was present through this rigid wall of the descending duodenum, accompanied by perienteric inflammation, which infiltrated the anterior pararenal space, gall bladder, and right colic flexure.	27086704
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Thus, in order to prevent cancer from developing, appropriate medical therapy aiming not only to relieve the clinical symptoms, but also to suppress chronic inflammation appears to be necessary.	27086804
Inflammation	Altered Intercellular Communication	In patients without complete resolution of mucosal inflammation, careful surveillance colonoscopy should be initiated in the early phase.	27086804
Inflammation	Altered Intercellular Communication	This case suggests the possibility that eosinophilic inflammation can occur concomitantly in the central airway and distal airway.	27086960
Cessation of life, Inflammation	Altered Intercellular Communication	The objective of this study is to characterize the cell death and cell survival response of the prostatic epithelium in response to inflammation.	27088546
Inflammation, Psoriasis	Altered Intercellular Communication	Meanwhile, the expression of IL-8 significantly decreases with clinically more severe psoriasis, perhaps making these factors candidate prognostic factors for psoriatic inflammation.	27088930
Inflammation, Arthritis	Altered Intercellular Communication	Sclerostin effectively blocked TNFa- but not interleukin-1-induced activation of p38, a key step in arthritis development, pointing to a previously unrealized protective role of sclerostin in TNF-mediated chronic inflammation.	27089204
Refractory anemias, Inflammatory	Altered Intercellular Communication	The possibility of anti-sclerostin antibody treatment worsening clinical RA outcome under chronic TNFa-dependent inflammatory conditions in mice means that caution should be taken both when considering such treatment for inflammatory bone loss in RA and when using anti-sclerostin antibodies in patients with TNFa-dependent comorbidities.	27089204
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Recently, lymphocyte-to-monocyte ratio (LMR) has emerged as a new indirect marker of inflammation which is associated with adverse outcomes in oncology and cardiovascular diseases.	27089433
Inflammation, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	A semisynthetic diterpenoid lactone inhibits NF-kB signalling to ameliorate inflammation and airway hyperresponsiveness in a mouse asthma model.	27089844
Inflammation, Asthma, Respiratory Hypersensitivity	Altered Intercellular Communication	SRS27 is the first known DDAG analogue effective in ameliorating inflammation and airway hyperresponsiveness in the ovalbumin-induced mouse asthma model.	27089844
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Immunity and inflammation processes are known to be of central importance in chronic heart failure (CHF).	27090038
Inflammation, Tauopathies, Dental Plaque, Trauma, Nervous System	Altered Intercellular Communication	RGNs are areas of concentrated neuronal injury, inflammation, and tauopathy and display unique features around b-amyloid plaque types.	27090093
Data types - Address	Altered Intercellular Communication	Leptin did not seem to be associated with IgE-mediated inflammation in AD.	27090367
Sleep Apnea, Obstructive	Altered Intercellular Communication	Oxidative Stress and Inflammation Differentially Elevated in Objective Versus Habitual Subjective Reduced Sleep Duration in Obstructive Sleep Apnea.	27091532
Inflammation	Altered Intercellular Communication	We postulate that oxidative stress and systemic inflammation biomarkers will be elevated in relation to short-term and long-term sleep duration reduction.	27091532
Inflammation, Obesity, Osage language	Altered Intercellular Communication	Even after consideration of obesity and OSA severity, inverse significant findings were observed such that reduced PSG-TST was associated with elevated MPO levels and SR-HSD with ox-LDL, suggesting differential up-regulation of oxidative stress and pathways of inflammation in acute versus chronic sleep curtailment.	27091532
Fever, CTCAE, Allergy - Charge Type Reason, Dyssomnias, Asthma, allergic inflammation, Speech Disorders	Altered Intercellular Communication	Children with asthma, hay fever, and food allergy may have several factors that increase their risk of speech disorder, including allergic inflammation, ADD/ADHD, and sleep disturbance.	27091599
Muscle tenderness, Inflammation, Certified Midwife	Altered Intercellular Communication	Expression of proinflammatory genes (eg, CCL8, TLR2) in the calvarial periosteum significantly increased in CM patients attesting to muscle tenderness, whereas expression of genes that suppress inflammation and immune cell differentiation (eg, IL10RA, CSF1R) decreased.	27091721
Inflammation, Sarcopenia	Altered Intercellular Communication	Sarcopenia, sarcopenic obesity and inflammation: Results from the 1999-2004 National Health and Nutrition Examination Survey.	27091774
PROS1 gene, Inflammation, Arthritis, Psoriatic	Altered Intercellular Communication	To investigate the association between clinical and ultrasonographic (US) evidence of inflammation in psoriatic arthritis (PsA), as well as to compare clinical and US remission criteria.	27091837
Inflammation	Altered Intercellular Communication	IL-15 is known to play an important role in neutrophil migration during inflammation.	27093372
Lymphoma	Altered Intercellular Communication	EBV-associated Peripheral T-Cell Lymphoma of Gastrointestinal Tract Presented With Widespread Chronic Inflammation: A Case Report.	27093448
Gastric Obstruction, Gastrointestinal tract structure, Gastrointestinal inflammation	Altered Intercellular Communication	We report a case of Epstein-Barr virus (EBV)-associated T-cell lymphoma of gastrointestinal (GI) tract from a 70-year-old white woman who initially presented with a widespread GI inflammation and gastric obstruction.	27093448
Inflammation	Altered Intercellular Communication	Initial biopsies of the GI tract showed severe chronic inflammation in the esophagus, stomach, and the small intestine.	27093448
T-Cell Lymphoma, Inflammation	Altered Intercellular Communication	Age-related immune senescence may have contributed to the uncontrolled GI inflammation and subsequent transformation to T-cell lymphoma.	27093448
Gingivitis, Inflammation	Altered Intercellular Communication	The gingival scores showed a mild inflammation and the prevalence of gingivitis was 91%.	27093564
Asthma, allergic inflammation	Altered Intercellular Communication	The mechanism of air pollution is not a classic allergic inflammation and could have differential effect on late-onset and early-onset asthma.	27094099
Psoriasis	Altered Intercellular Communication	Interleukins are involved in the development of psoriasis lesions through Th-17-associated inflammation.	27094154
Inflammation	Altered Intercellular Communication	Peripheral inflammation has been associated with adverse effects on cognition and brain structure in late life, a process called 'inflammaging.'	27094339
Inflammation	Altered Intercellular Communication	Peripheral inflammation related to lower fMRI activation during a working memory task and resting functional connectivity among older adults: a preliminary study.	27094339
Inflammation	Altered Intercellular Communication	Peripheral inflammation has been associated with adverse effects on cognition and brain structure in late life, a process called 'inflammaging.'	27094339
Inflammation, Impaired cognition	Altered Intercellular Communication	Identifying biomarkers of preclinical cognitive decline is critical in the development of preventative therapies, and peripheral inflammation may be able to serve as an indicator of cognitive decline.	27094339
Inflammation	Altered Intercellular Communication	However, little is known regarding the relationship between peripheral inflammation and brain structure and function among older adults.	27094339
Inflammation	Altered Intercellular Communication	Long-term subclinical inflammation may be the mechanism of this extraordinary aggressive clinical course.	27094461
Inflammation, Malnutrition, Hyponatremia	Altered Intercellular Communication	Unraveling the relationship between mortality, hyponatremia, inflammation and malnutrition in hemodialysis patients: results from the international MONDO initiative.	27094625
Inflammation, Malnutrition, Fluid imbalance, Hyponatremia	Altered Intercellular Communication	It is not well known to which extent the comorbidities, malnutrition, fluid status imbalance and inflammation are related to hyponatremia and affect outcomes.	27094625
Inflammation, Hyponatremia	Altered Intercellular Communication	Hyponatremia and inflammation were defined as serum sodium levels <135 mEq/l and C-reactive protein levels>6.0 mg/l, respectively.	27094625
Hypernatremia, Inflammation, Malnutrition, Hyponatremia	Altered Intercellular Communication	Hyponatremia was predicted by the presence of malnutrition (odds ratio (OR)=1.49 (95% confidence interval (CI)=1.30-1.70), inflammation (OR=1.44 (95% CI=1.26-1.64)) and fluid overload ((>+1.1 l to +2.5 l) OR=0.73 (95% CI=0.62-0.85)) but not by fluid depletion (OR=1.34 (95% CI=0.92-1.96)).	27094625
Hypernatremia, Inflammation, Malnutrition, Hyponatremia	Altered Intercellular Communication	Malnutrition, inflammation, fluid overload, fluid depletion and hyponatremia (hazard ratio=1.70 (95% CI=1.46-1.99)) were independent predictors for all-cause mortality.	27094625
Hypernatremia, Inflammation, Malnutrition, HD Term Type, Hyponatremia	Altered Intercellular Communication	In HD patients, hyponatremia is associated with malnutrition, inflammation and fluid overload.	27094625
Inflammation, Malnutrition, Hyponatremia, Congenital Abnormality	Altered Intercellular Communication	Hyponatremia maintained predictive for all-cause mortality after adjustment for malnutrition, inflammation and fluid status abnormalities.	27094625
Thyroid Diseases, Diabetes, Autoimmune, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Common autoimmune biomarkers, thyroid hormonal abnormalities, and beta cells dysfunction in patients with latent autoimmune diabetes in adults with type II diabetes mellitus.	27094870
Inflammatory, Inflammatory abnormality of the eye, Behcet Syndrome	Altered Intercellular Communication	Behcet's disease is a progressive diffuse inflammatory vasculitis characterized by recurrent oral and genital ulceration and ocular inflammation.	27095010
Inflammatory abnormality of the eye, Diarrhea	Altered Intercellular Communication	She also had a history of recurrent diarrhea with a single episode of ocular inflammation in the recent past.	27095010
Inflammation, Injury of gastrointestinal tract, immunoglobulin A, Colitis	Altered Intercellular Communication	Adult mice colonized with LGG showed increased IgA production and decreased susceptibility to intestinal injury and inflammation induced in the dextran sodium sulfate model of colitis.	27095077
Inflammation, Injury of gastrointestinal tract, immunoglobulin A	Altered Intercellular Communication	Thus, neonatal colonization of mice with LGG enhances intestinal functional maturation and IgA production and confers lifelong health consequences on protection from intestinal injury and inflammation.	27095077
Respiratory Distress Syndrome, Adult, Inflammation, Lung Injury, Respiratory Distress Syndrome, Newborn, Pneumonia	Altered Intercellular Communication	Acute respiratory distress syndrome (ARDS) is a heterogeneous syndrome that occurs as a result of various risk factors, including either direct or indirect lung injury, and systemic inflammation triggered also by severe pneumonia (SP).	27095254
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Complications of Diabetes Mellitus	Altered Intercellular Communication	Low-grade systemic inflammation is considered to participate in the progression of type 2 diabetes (T2D) and in diabetic complications.	27095356
Inflammation, Histologic type, Pain Distress Question	Altered Intercellular Communication	No significant correlations between the degree of inflammation, the histotype or invasiveness of SCCs, and the intensity of pain were found.	27096539
Inflammation, Dentition, Mixed, Granulomatous disorder, Vasculitis, CTCAE, Orbital Pseudotumor	Altered Intercellular Communication	Thirty-three (47.1%) had specific inflammation of the following subtypes: idiopathic sclerosing inflammation (n = 9), granulomatous disorders (n = 8), transitional lesions (n = 5), vasculitis (n = 4), and others (n = 7).	27097061
Granulation procedure, Neoplasms, Common wart, Granulomatous inflammation, Squamous cell carcinoma, Cutaneous Fibrous Histiocytoma	Altered Intercellular Communication	The changes of CPH overly traumatized neoplasms [ie, a poroma, squamous cell carcinoma (2), dermatofibroma], verruca vulgaris (3), inflammatory processes (lichen amyloid and granulomatous inflammation secondary to a ruptured infundibular cyst), and scar and fibrosing granulation tissue from previous procedures.	27097239
Hidradenitis Suppurativa, Abscess, Inflammation	Altered Intercellular Communication	Hidradenitis suppurativa (HS) is characterized by chronic inflammation, recurrent abscesses, and scarring.	27097631
Inflammation, Hypertension, CTCAE, Dyssomnias	Altered Intercellular Communication	Linking childhood abuse and hypertension: sleep disturbance and inflammation as mediators.	27098168
Inflammation, Hypertension, CTCAE, Dyssomnias	Altered Intercellular Communication	Childhood abuse was significantly related to both body mass index and sleep disturbance, which, both in turn, were significantly associated with inflammation, which was subsequently associated with hypertension status.	27098168
Inflammation, Hypertension, CTCAE, Dyssomnias	Altered Intercellular Communication	Sleep disturbance, body mass, and inflammation may be independent, intermediate steps between childhood abuse and subsequent hypertension that may be amenable to biobehavioral interventions.	27098168
Inflammation	Altered Intercellular Communication	Paleolithic and Mediterranean Diet Pattern Scores Are Inversely Associated with Biomarkers of Inflammation and Oxidative Balance in Adults.	27099230
Inflammation, Primary malignant neoplasm, Chronic disease	Altered Intercellular Communication	Chronic inflammation and oxidative balance are associated with poor diet quality and risk of cancer and other chronic diseases.	27099230
Discordance	Altered Intercellular Communication	A diet-inflammation/oxidative balance association may relate to evolutionary discordance.	27099230
Inflammation	Altered Intercellular Communication	These findings suggest that diets that are more Paleolithic- or Mediterranean-like may be associated with lower levels of systemic inflammation and oxidative stress in humans.	27099230
Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Elevated serum fibroblast growth factor-23 (FGF23), an endogenous hormone, is associated with disturbed mineral homeostasis, cardiovascular disease, and chronic kidney disease.	27100793
glycation, Myeloid Leukemia, Chronic, Inflammation	Altered Intercellular Communication	Receptor for advanced glycation end products (RAGE) expressed on adipocytes and immune cells can bind to ligand N(e)-(carboxymethyl)-lysine (CML) and trigger dysregulation of adipokines and chronic inflammation.	27100837
Inflammation, Coronary Artery Disease, Atherosclerosis	Altered Intercellular Communication	Chronic inflammation promotes atherosclerosis and is a prognostic factor in coronary artery disease (CAD).	27101443
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Increased oxidative stress and inflammation may play an important role in the high mortality of individuals with metabolic syndrome.	27101758
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Lifecourse socioeconomic status and type 2 diabetes: the role of chronic inflammation in the English Longitudinal Study of Ageing.	27101929
Inflammation, Ulceration, CTCAE, Dental Plaque, Cerebrovascular accident	Altered Intercellular Communication	Carotid intraplaque hemorrhage is associated with stroke, plaque thickness, stenosis, ulceration, and adventitial inflammation.	27102316
Inflammation, Eating	Altered Intercellular Communication	Change in serum lipids and markers of inflammation did not predict EAT progression.	27102490
Autoimmune Diseases, Vasculitis, AAVS1 gene	Altered Intercellular Communication	Anti-neutrophil cytoplasmic antibodies associated vasculitides (AAV) is a group of autoimmune diseases, characterized by small vessel inflammation.	27102815
Inflammation	Altered Intercellular Communication	During inflammation, P-selectin expressed on activated endothelial cells and platelets mediates rolling adhesion of leukocytes.	27102967
Inflammation, Damage	Altered Intercellular Communication	Soluble CD14 in cerebrospinal fluid is associated with markers of inflammation and axonal damage in untreated HIV-infected patients: a retrospective cross-sectional study.	27103116
Inflammation, Impaired cognition	Altered Intercellular Communication	Inflammation in the cerebrospinal fluid (CSF) has been associated with cognitive impairment, and CSF neurofilament light chain protein (NFL) and CSF neopterin concentrations are increased in those patients.	27103116
Inflammation, HIV Infections	Altered Intercellular Communication	Microbial translocation in HIV infection has been suggested to contribute to chronic inflammation, and lipopolysaccharide (LPS) and soluble CD14 (sCD14) are markers of microbial translocation and the resulting monocyte activation, respectively.	27103116
Inflammation, Damage, HIV Infections	Altered Intercellular Communication	We hypothesised that microbial translocation contributes to inflammation and axonal damage in the central nervous system (CNS) in untreated HIV infection.	27103116
Inflammation, Damage	Altered Intercellular Communication	CSF sCD14 were associated with markers of CNS inflammation and axonal damage.	27103116
Inflammation	Altered Intercellular Communication	This suggest that microbial translocation might be a driver of systemic and CNS inflammation.	27103116
Inflammation, Bothered by Vomiting, Diarrhea, Nausea, Dysgeusia, CTCAE, Fatigue	Altered Intercellular Communication	The most common treatment-related adverse events associated with gedatolisib were nausea (53%), mucosal inflammation (50%), decreased appetite (40%), diarrhea (38%), fatigue (35%), and dysgeusia and vomiting (each 30%).	27103175
Inflammation, Metabolic Syndrome X, Hyperglycemia, Hypertriglyceridemia, Hypertension, CTCAE	Altered Intercellular Communication	This association was robust to adjustments for other components of the metabolic syndrome (hypertriglyceridaemia, hypertension, hyperglycaemia and systemic inflammation).	27103388
Inflammation, Weight decreased, Obesity	Altered Intercellular Communication	Continued research into racial and sex differences in the relationship between obesity, inflammation, and health risks may ultimately lead to more personalized weight loss recommendations.	27103770
Granuloma, Swelling, Foreign-Body Reaction, Inflammation	Altered Intercellular Communication	In our opinion the painful swelling of the knee was due to a displacement of the pin that had been accidentally lodged in the soft tissues instead of the bone causing a foreign-body reaction resulting in granuloma formation with local inflammation.	27104331
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Vitamin D is suggested to play a role in airway and systemic inflammation in chronic obstructive pulmonary disease (COPD).	27105006
Inflammation	Altered Intercellular Communication	In addition, the increased expression of two major inflammatory cytokines in the EF in the L group may indicate that SEL is causally related to chronic inflammation.	27105459
Communicable Diseases, Gastrointestinal tract vascular insufficiency, Inflammation, Non-obstructive	Altered Intercellular Communication	The most frequent cause of PI was intestinal ischemia (n = 80,53.7 %), followed by infection (n = 18,12.1 %), obstructive (n = 12,8.1 %) and non-obstructive (n = 10,6.7 %) bowel dilatation, unknown aetiologies (n = 8,5.4 %), drugs (n = 8,5.4 %), inflammation (n = 7,4.7 %), and others (n = 6,4 %).	27106233
Malignant neoplasm of esophagus, Inflammation	Altered Intercellular Communication	Endoscopic ultrasonography suggested esophageal cancer, and chest computed tomography showed a mass in the lower esophagus surrounded by inflammation.	27106429
Inflammation, Metabolic Diseases, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Epidemiological and genetic studies have identified metabolic disorders and inflammation as risk factors for Alzheimer's disease (AD).	27106634
Inflammation, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Evidence in obesity and type-2 diabetes suggests a role for a metabolic inflammasome ("metaflammasome") in mediating chronic inflammation in peripheral organs implicating IKKb (inhibitor of nuclear factor kappa-B kinase subunit beta), IRS1 (insulin receptor substrate 1), JNK (c-jun N-terminal kinase), and PKR (double-stranded RNA protein kinase).	27106634
Inflammation	Altered Intercellular Communication	Inhibition of both TLR and IL signaling pathways may prevent joint inflammation and destruction.	27108590
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	CONCLUSIONS In treating persistent inflammation in the course of glaucoma, antiglaucoma drugs may increase the permeability of the blood-ocular barrier, which may be connected with the lower concentration of serum ceruloplasmin in the glaucoma patients group.	27109647
ARCN1 gene, Inflammation, Lung diseases	Altered Intercellular Communication	The German COPD cohort study COSYCONET ("COPD and SYstemic consequences-COmorbidities NETwork") investigates the interaction of lung disease, comorbidities and systemic inflammation.	27109808
methyldopa, Inflammation	Altered Intercellular Communication	Chronic oxidative stress and subacute inflammation have been implicated as causes of age-related macular degeneration (AMD).	27110092
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Angiopoietins (Angs) play a pivotal role in angiogenesis and inflammation, and are associated with prognosis in malignancies.	27111031
Inflammation	Altered Intercellular Communication	Background Previous studies proposed that inflammation, oxidative stress, and impaired endothelial dysfunction have a crucial role in occurrence of saphenous vein graft (SVG) disease (SVGD).	27111497
Refractory anemias, Inflammation	Altered Intercellular Communication	Since SNS and HPA axis are activated in RA, inflammation might be accompanied by water retention.	27112146
Orbital Pseudotumor	Altered Intercellular Communication	Idiopathic orbital inflammation or orbital pseudotumor is rare in the pediatric population and may present with ocular findings not normally seen in the adult population.	27112170
Panuveitis, Orbital Pseudotumor	Altered Intercellular Communication	The authors report the case of a 14-year-old boy with idiopathic orbital inflammation who presented with bilateral panuveitis to highlight the features that make this diagnosis more difficult in the pediatric population.	27112170
Inflammation, Ischemic stroke	Altered Intercellular Communication	Low triiodothyronine: A new facet of inflammation in acute ischemic stroke.	27112304
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Inflammation is recognized as a key contributor to the pathophysiology of stroke.	27112304
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Low fT3 concentrations may be involved in the pathogenic pathway linking inflammation to stroke severity in AIS patients.	27112304
Inflammation, Asthma	Altered Intercellular Communication	We have shown that simultaneously increased local (Feno) and systemic (blood eosinophil) markers of type 2 inflammation related to a higher likelihood of BHR and uncontrolled asthma in a large cohort of young asthmatic patients.	27113848
Inflammation, vascular inflammations, SLC16A1 wt Allele	Altered Intercellular Communication	Serum hs-CRP, a systemic inflammation marker, and sVCAM-1, a vascular inflammation marker, reduced significantly in the flaxseed oil group at the end of week 8 compared to baseline (P < 0.05), and the reductions were significant in comparison with the MCT oil group (P < 0.05).	27115157
methyldopa, Age related macular degeneration, Chronic inflammation	Altered Intercellular Communication	Our previous study indicated that Ab-induced Retinal Pigment Epithelial (RPE) cell senescence may be associated with chronic inflammation in age-related macular degeneration (AMD).	27115165
methyldopa, Inflammation	Altered Intercellular Communication	In this AMD mouse model, Ab deposition and RPE senescence may be associated with AMD development, and RPE senescence is likely a mechanistic link between Ab deposition and inflammation.	27115165
Cessation of life, Chagas Disease, Cerebrovascular accident	Altered Intercellular Communication	Inflammation Enhances the Risks of Stroke and Death in Chronic Chagas Disease Patients.	27115869
Inflammation, Brain Injuries	Altered Intercellular Communication	Inflammation has been recognized as a key component in all ischemic processes, including the intravascular events triggered by vessel interruption, brain damage and repair.	27115869
Communicable Diseases, Inflammation	Altered Intercellular Communication	Given this, it is of particular importance to control intraoperative and postoperative intraocular pressure, infection, and inflammation which will contribute to decrease in the incidence of vitreoretinal complications after PK.	27115992
Inflammation	Altered Intercellular Communication	Its dysfunction associated with inflammation also binds to systemic complications.	27116855
Breast Carcinoma, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Obesity and metabolic syndrome are risk and prognostic factors for breast cancer (BC) and are associated with chronic inflammation.	27117160
Inflammation, Triple Negative Breast Neoplasms, Obesity	Altered Intercellular Communication	Before menopause, triple-negative cancers were related to obesity and chronic inflammation, and aggressive luminal subtypes to abdominal adiposity.	27117160
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Systemic inflammation is an important risk factor for cardiovascular diseases and inequalities by race/ethnicity, gender, and education have been documented.	27117593
ARCN1 gene, Airway structure, Pulmonary Emphysema, Chronic Obstructive Airway Disease, Chronic lung disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a chronic lung disease characterized by chronic airway inflammation and emphysema, and is caused by exposure to noxious particles or gases, e.g.	27117828
Inflammation, Trichinellosis	Altered Intercellular Communication	Matrix metalloproteinase (MMP)-9: A realiable marker for inflammation in early human trichinellosis.	27117947
Inflammation	Altered Intercellular Communication	In conclusion, MMP-9 might be considered as a marker of inflammation in T. britovi patients.	27117947
Inflammation, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Autoimmune reaction, Necrosis	Altered Intercellular Communication	ANCA-associated vasculitis are severe autoimmune pathologies that are characterized by inflammation and necrosis of the small vessels.	27118022
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	In collagenase-induced OA knees, analyses of CatWalk, 2-deoxyglucose-probed fluorescence imaging, and mCT revealed that affected knees of TgHSP60 mice showed minor footprint irregularity, joint inflammation, and osteophyte formation.	27118120
Coronary Artery Disease, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	MHR as a novel inflammation-based marker seemed to be an independent predictor of severity of coronary artery disease and future cardiovascular events in patients with ACS.	27118231
Inflammation	Altered Intercellular Communication	As a result of the relapsing B. cereus peritonitis diagnosis and a CT scan showing contraction of the peritoneum after longstanding inflammation, the peritoneal catheter was removed and the patient converted to haemodialysis.	27118739
Communicable Diseases, Inflammation	Altered Intercellular Communication	We aimed to explore the contribution of persisting inflammation to recovery, and investigated the potential role of human cytomegalovirus (HCMV) infection in its pathogenesis.	27118812
Renal Insufficiency, Inflammation, Chronic heart failure	Altered Intercellular Communication	Galectin-3 in patients with chronic heart failure: association with oxidative stress, inflammation, renal dysfunction and prognosis.	27119370
Abnormal renal function, Inflammation	Altered Intercellular Communication	Galectin-3 shows positive correlation with markers of oxidative stress, inflammation and kidney dysfunction.	27119370
Cessation of life, Inflammation	Altered Intercellular Communication	The patients had increased levels of most inflammatory biomarkers, albeit not all statistically significant, both at study entry and close to death, indicating ongoing inflammation.	27119533
Inflammation, Fibrosis Assessment, Heart failure	Altered Intercellular Communication	Galectin-3 (Gal-3) is involved in cardiac inflammation and fibrosis, and is in use as a biomarker that indicates increased risk in heart failure.	27120522
ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by slowly progressive airflow limitaion, chronic lung inflammation and associated systemic manifestations.	27121518
ARCN1 gene, Tumor necrosis, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The objective of this preliminary study was to investigate the levels of high sensitivity C reactive protein (hs CRP) and tumour necrosis factor-a (TNF-a) as markers of systemic inflammation and assessment of systemic vascular reactivity that may play an important role in development of cardiovascular disease in COPD patients.	27121518
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumour necrosis factor-a (TNF-a) and hs CRP were measured as markers of inflammation.	27121518
Inflammation, Impaired cognition	Altered Intercellular Communication	Pro-inflammatory markers like matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) and S-100 Beta (S100B) may have a role in the early inflammation and cognitive decline following CEA.	27121520
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Inflammation in arterial walls leads to coronary artery disease (CAD).	27121596
Vasculitis, Coronary Arteriosclerosis, Coronary Artery Disease	Altered Intercellular Communication	Together, they suggest that low vascular SPMs may enable progression of chronic vascular inflammation predisposing to coronary atherosclerosis and to thrombosis.-Elajami, T. K., Colas, R. A., Dalli, J., Chiang, N., Serhan, C. N., Welty, F. K. Specialized proresolving lipid mediators in patients with coronary artery disease and their potential for clot remodeling.	27121596
Neurodegenerative Disorders, Inflammation, Presenile dementia, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Notably, inflammation, MMPs, and AMPs are also involved in the etiopathogenesis of neurodegenerative disorders including certain forms of dementia such as Alzheimer disease (AD).	27121663
Refractory anemias, Arthritis	Altered Intercellular Communication	Early RA management should address psychosocial factors and comorbidities, as well as joint inflammation.	27121777
Pyogenic granuloma, Injury of nose	Altered Intercellular Communication	Our data further supports prior studies, suggesting that altered hormonal activity and nasal injury may increase the risk of developing nasal pyogenic granuloma.	27122134
methyldopa, Inflammation, Humor	Altered Intercellular Communication	Elevated levels of inflammation-related chemokines, including CXCL10, CCL14, CXCL16, CXCL7, and CCL22, in the aqueous humor of AMD patients may suggest a pathogenic role for inflammation.	27122966
Pituitary Neoplasms, OXSM gene, Acromegaly	Altered Intercellular Communication	As the simultaneous occurrence of KS and acromegaly is rare, and the association between them remains unclear, we suggest that complete pituitary hormonal screening and conventional pituitary MRI should be essential for patients with KS to screen for pituitary tumor.	27124035
Metastatic Gastric Adenocarcinoma	Altered Intercellular Communication	A Prognostic Model Using Inflammation- and Nutrition-Based Scores in Patients With Metastatic Gastric Adenocarcinoma Treated With Chemotherapy.	27124056
Sepsis, Inflammation, Bacterial Infections	Altered Intercellular Communication	Concentrations of TWEAK (but not GITRL) were further decreased in patients with sepsis and correlated with routinely used markers of inflammation and bacterial infection such as C-reactive protein, procalcitonin and Interleukin-6.	27124414
Retinal Detachment, Inflammation	Altered Intercellular Communication	On examination, anterior segment examination was quiet without any inflammation, anterior vitreous face showed 1+ cells, and dilated funduscopy revealed bilateral symmetrical serous retinal detachments along the posterior pole.	27124790
Inflammation, Fibrosis Assessment, Cutaneous Small Vessel Vasculitis	Altered Intercellular Communication	Histopathologic findings of small-vessel vasculitis, dermal fibrosis, and plasma cell infiltrates were uniformly present, and eosinophilic inflammation was frequent.	27124923
Inflammation	Altered Intercellular Communication	The evolving disease shows chronic inflammation of the synovium, which is a self-maintained process and an immunologically induced phenomenon.	27125075
Inflammation, Damage, Peripheral	Altered Intercellular Communication	The chronic inflammation of the synovium forms granulation tissue that invades peripheral joints towards the center and causes ligament cartilage and bone damage.	27125075
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	In atlas and axis joints, rheumatoid arthritis causes the inflammation of bursa, synovium and joint capsule and leads to synovial pannus formation.	27125075
Hyponatremia	Altered Intercellular Communication	This study provides data supporting the view that mild hyponatremia during acute illnesses is related to a systemic inflammatory condition.	27125438
Arthritis	Altered Intercellular Communication	There was marked reduction in gut and peripheral joint inflammation, and less IFNg-producing and IL-17-producing CD8+ T cells, in Tbx21-/- compared with wild-type SKG mice.	27125523
APP gene, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Inflammation of the aortic wall is recognised as a key pathogenesis of abdominal aortic aneurysm (AAA).	27126477
Necrotizing granulomatous inflammation, B-Cell Lymphomas	Altered Intercellular Communication	Diffuse large B cell lymphoma with chronic granulomatous inflammation.	27126666
Granuloma, Neoplasms, Necrotizing granulomatous inflammation, Lymphoma, B-Cell Lymphomas	Altered Intercellular Communication	We report a case of diffuse large B cell lymphoma with chronic granulomatous inflammation to highlight awareness of obscure tumour cells within the granuloma, to avoid delay in diagnosis and management of lymphoma.	27126666
Necrotizing granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	Chest X-ray showed an anterior mediastinal mass and computed tomography (CT)-guided biopsy was reported as chronic granulomatous inflammation suggestive of tuberculosis.	27126666
ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	Wingless/integrase-1 (WNT) signalling is associated with lung inflammation and repair, but its role in chronic obstructive pulmonary disease (COPD) pathogenesis is unclear.	27126693
vascular inflammations	Altered Intercellular Communication	Reduced miR-126 expression was accompanied by increased vascular inflammation as evident from the levels of vascular adhesion molecule-1 and fibrinogen, as well as leukocyte counts.	27127202
Airway structure, ARCN1 gene	Altered Intercellular Communication	Erythromycin was beneficial and reduced airway inflammation in COPD patients.	27127346
Airway structure	Altered Intercellular Communication	Underlying mechanisms may involve inhibition of IL-17 and IL-23 mediated airway inflammation.	27127346
Inflammation, Injury of kidney	Altered Intercellular Communication	So we hypothesized that the infiltration of neutrophils, inflammation factors, and aging markers , which were modulated by functional networks, induced the immune response and renal injury.	27127888
Inflammation	Altered Intercellular Communication	Inflammasome activation, with subsequent release of pro-inflammatory cytokines interleukin-1b (IL-1b) and IL-18, has recently been implicated in atherosclerosis-associated inflammation.	27129183
Inflammation	Altered Intercellular Communication	An immune phenotype characterized by increased immune activation, systemic inflammation, and accumulation of late-differentiated memory CD57(+) CD28(-) T cells has been associated with comorbidities in the elderly.	27129782
Inflammation	Altered Intercellular Communication	Periostin levels and eosinophilic inflammation in poorly-controlled asthma.	27130294
Inflammation, dupilumab	Altered Intercellular Communication	Dupilumab, a fully human anti-interleukin-4 receptor a monoclonal antibody, inhibits interleukin-4 and interleukin-13 signalling, key drivers of type-2-mediated inflammation.	27130691
Inflammation	Altered Intercellular Communication	Broccoli sprouts (BS) are the richest source of sulforaphane (SFN), which is a potent inducer of phase II enzymes, which play a critical role in preventing oxidative stress (OS) and inflammation.	27130714
Asthma, Pneumonitis, Atopy	Altered Intercellular Communication	Ingestion of whole BS for 3 days does not appear to improve eosinophilic pulmonary inflammation, inflammatory and OS biomarkers, or clinical features of asthma among atopic adults with asthma despite resulting in a marked increase in serum SFN levels.	27130714
Autoimmune Diseases, Inflammation, Thickening of left ventricular wall, Mitral Valve	Altered Intercellular Communication	Immunological and inflammatory processes in systemic autoimmune disease may not only cause pericardium inflammation, but may also cause mitral valve deterioration and left ventricular wall thickening.	27131766
Sandawe language, Inflammation	Altered Intercellular Communication	Immunological and inflammatory processes in SAD may not only cause pericardium inflammation, but may also cause MV deterioration and LV wall thickening.	27131766
Vascular Diseases, Dysplasia, Inflammation, Brain Neoplasms	Altered Intercellular Communication	Physiological (11)C-Met uptake, anatomical variations, vascular disorders, non-tumorous lesions such as inflammation or dysplasia, benign brain tumors and patient condition during (11)C-Met PET examination can potentially affect the image interpretation and cause false positives and negatives.	27134530
Acute and chronic inflammation	Altered Intercellular Communication	Chronic active mucosal inflammation accompanied 37.5% of the cases.	27136106
Inflammation, Ulceration, CTCAE, Distortion, Congestion	Altered Intercellular Communication	No statistically significant difference was found between parasite subspecies regarding presence of inflammation, lymphoid aggregates, architectural distortion, congestion, ulceration and increase of eosinophils.	27136106
Inflammation, Granuloma	Altered Intercellular Communication	Parasites induce nonspecific inflammation, slight mucosal architectural changes, mild eosinophilic infiltrate or granuloma formation.	27136106
Lichen - organism, Inflammation, Tinea Capitis	Altered Intercellular Communication	Endothrix tinea capitis owing to Trichophyton tonsurans commonly produces generalized scaling and localized perifollicular inflammation reminiscent of lichen planopilaris.	27136624
Inflammation, Transplant glomerulopathy, graft loss	Altered Intercellular Communication	Human leukocyte antigens (HLA) class II donor-specific antibodies (DSAs) are associated with microcirculation inflammation, transplant glomerulopathy and ultimately graft loss.	27137749
Inflammation, Radiculopathy, Polyneuropathy	Altered Intercellular Communication	On multivariate logistic regression analysis duration of symptoms since the onset (OR 1.007; 95 % CI 1-28, p = 0.01), polyneuropathy and radiculopathy (OR 5.4; 95 % CI 1.002-1.013, p = 0.044), cerebrospinal fluid (CSF)/serum glucose rate (OR 0.001; 95 % CI 000-0.067, p = 0.001), and CSF protein (OR 2.5; 95 % CI 2.3-2.7, p = 0.0001) were associated with diffuse inflammation.	27138335
Inflammatory abnormality of the eye, metabolic deficiency	Altered Intercellular Communication	Metabolic deficiency of o-3 tear film lipids may be a driver of chronic ocular surface inflammation in DE.	27138739
Inflammation, Thrombosis	Altered Intercellular Communication	Recently, platelet-to-lymphocyte ratio (PLR) has emerged as a new marker of worse outcomes linking inflammation and thrombosis.	27138871
Inflammation, Non-Small Cell Lung Carcinoma, Hypoxia, Neoplasms	Altered Intercellular Communication	Prognostic value of blood-biomarkers related to hypoxia, inflammation, immune response and tumour load in non-small cell lung cancer - A survival model with external validation.	27139126
Inflammation, Non-Small Cell Lung Carcinoma, Hypoxia, Neoplasms	Altered Intercellular Communication	Improve the prognostic prediction of clinical variables for non-small cell lung cancer (NSCLC), by selecting from blood-biomarkers, non-invasively describing hypoxia, inflammation and tumour load.	27139126
Diabetic Nephropathy, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Common risk predictors included increasing age, cardiovascular disease history, primary diabetic nephropathy, low blood pressure, and inflammation.	27140339
Inflammation	Altered Intercellular Communication	Our study demonstrates that the targeted increase of gland permeability not only resulted in the restoration of secretory gland function but also resolved the hallmark salivary gland inflammation and systemic inflammation associated with disease.	27140635
Thrombosis	Altered Intercellular Communication	In contrast to patients without device thrombosis, all patients with device thrombosis had a pre-existing systemic inflammatory condition.	27140700
Thrombosis	Altered Intercellular Communication	Patients with pre-existing systemic inflammatory conditions are at risk of device thrombosis during DT.	27140700
Inflammation, Hypoglycemia, Obesity	Altered Intercellular Communication	Significant correlations were found between E-selectin and age, markers of glycaemia and inflammation, central obesity and lipid variables.	27141013
Inflammation, Corneal edema	Altered Intercellular Communication	Clinical improvement of coin-shaped lesions, other types of keratic precipitates, corneal oedema, and anterior chamber inflammation was confirmed at the 4-week visit in all seven eyes.	27142389
Inflammation, Friedreich Ataxia	Altered Intercellular Communication	Dorsal root ganglia in Friedreich ataxia: satellite cell proliferation and inflammation.	27142428
Multiple Organ Failure	Altered Intercellular Communication	Immunoglobulin G4-related disease (IgG4-RD) is a recently recognized inflammatory condition with single- or multi-organ involvement.	27142509
Inflammation, Shock, Cardiogenic	Altered Intercellular Communication	Extracellular peroxiredoxin 1 (Prdx1) has been implicated to play a pivotal role in regulating inflammation; however, its function in tissue hypoxia-induced inflammation, such as severe cardiogenic shock patients, has not yet been defined.	27142532
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Increased Kappa/Lambda Hybrid Antibody in Serum Is a Novel Biomarker Related to Disease Activity and Inflammation in Rheumatoid Arthritis.	27143816
Refractory anemias	Altered Intercellular Communication	The increased k/l hybrid antibodies were associated with inflammatory conditions in RA.	27143816
Inflammation, Lymphoma	Altered Intercellular Communication	In five of seven patients with multiple biopsies at different time-intervals, the lymphoma was misinterpreted as representing chronic inflammation on an earlier biopsy.	27144366
Inflammation, Hyperplasia	Altered Intercellular Communication	In sinonasal biopsies with predominantly small lymphocytic infiltrates with admixed chronic inflammation, focal hypercellularity, focal surface ulceration or microscopic bone invasion by small lymphoid cells should alert pathologists to the possibility of small-cell predominant ENKTCL.	27144366
Inflammation, Obesity	Altered Intercellular Communication	Bisphenol A Promotes Adiposity and Inflammation in a Nonmonotonic Dose-response Way in 5-week-old Male and Female C57BL/6J Mice Fed a Low-calorie Diet.	27145005
Inflammation	Altered Intercellular Communication	BPA exposure increased circulating inflammatory factors and the local inflammation in white adipose tissues in both genders fed a chow diet, but not under high-fat diet.	27145005
Inflammation, Obesity	Altered Intercellular Communication	Obesity and Age-Related Changes in Markers of Oxidative Stress and Inflammation Across Four Generations.	27145150
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a condition characterized by systemic low-grade inflammation that could increase the production of nitric oxide (NO), of which arginine is the sole precursor.	27146652
Inflammation, Neoplasms	Altered Intercellular Communication	Inflammation is a critical component involved in tumor progression.	27146881
Massive Osteolyses, Inflammation, Prostate carcinoma, Gall Bladder Diseases	Altered Intercellular Communication	Chronic inflammation and abnormal cholesterol metabolism are involved in the pathogenesis of gallbladder stone disease (GSD) and that of prostate cancer in experimental studies.	27147576
Communicable Diseases, Fibrosis Assessment, Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Profiling analyses indicated that HCV infection differentially regulated the expression of 72 miRNAs by at least 2-fold, including miRNAs that were previously described to target genes associated with inflammation, fibrosis, and cancer development.	27147737
Colorectal Carcinoma	Altered Intercellular Communication	Relationship Between Chronic Inflammation and the Stage and Histopathological Size of Colorectal Carcinoma.	27147782
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	The association of inflammatory reactions with almost all types of cancer supports the concept that inflammation is a critical component of tumor progression.	27147782
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The present study aimed to evaluate the relationship of serum markers of chronic inflammation with the stage of and histopathological size of colorectal carcinoma (CRC).	27147782
Inflammation, Colorectal Carcinoma, Neoplasms	Altered Intercellular Communication	It was confirmed that increasing markers of inflammation followed increasing stages of colorectal cancer, depth of tumor invasion and the occurrence of metastatic disease.	27147782
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The study results point to an increase in the degree of chronic inflammation throughout the progression of colorectal cancer.	27147782
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The most consistent marker of chronic inflammation that accompanies the progression of colorectal carcinoma is CRP.	27147782
Pancreatic carcinoma	Altered Intercellular Communication	Clinical Implication of Inflammation-Based Prognostic Score in Pancreatic Cancer: Glasgow Prognostic Score Is the Most Reliable Parameter.	27149487
Pancreatic carcinoma	Altered Intercellular Communication	A variety of systemic inflammation-based prognostic scores have been explored; however, there has been no study to clarify which score could best reflect survival in resected pancreatic cancer patients.Between 2002 and 2014, 379 consecutive patients who underwent curative resection of pancreatic cancer were enrolled.	27149487
Duodenum, Neoplasms, Tumor Cell Invasion, Pancreatic carcinoma	Altered Intercellular Communication	There was also statistically significant correlation between the GPS score and tumor location (head), tumor size (>=2.0 cm), bile duct invasion, and duodenal invasion.Our study demonstrated that the GPS could be an independent predictive marker and was superior to other inflammation-based prognostic scores in patients with resected pancreatic cancer.	27149487
Inflammation	Altered Intercellular Communication	The patients with adult-onset inflammation of the middle ear, inner ear or both should undergo careful examinations, and they should be closely followed even if the diagnosis is uncertain.	27149708
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	We studied activation of hemostatic reactions together with mechanisms of systemic inflammation and genetic factors responsible for thrombogenic risk in 65 patients suffering exacerbation of chronic obstructive pulmonary disease with 2 or 3 positive criteria proposed by N.Anthonisen at al.	27149808
Inflammation, Tumor necrosis, Thrombin Time Test Device	Altered Intercellular Communication	The levels of indicators of systemic inflammation, such as C-reactive protein and tumour necrosis factor-alpha, increased concurrently with those of homocysteine, endothelin-1, Willebrand factor plasminogen activator inhibitor type 1, and thrombin-antithrombin complex (marker of thrombinemia).	27149808
Colorectal Carcinoma, peripheral blood, Colitis	Altered Intercellular Communication	CES-2 expression was analyzed by immunohistochemistry in colorectal cancer (CRC) compared to colonic inflammation as well as in liver and peripheral blood.	27149931
Primary malignant neoplasm, Gastrointestinal inflammation	Altered Intercellular Communication	Further studies should elucidate the role of CES-2(+) plasma cells in intestinal inflammation and cancer.	27149931
Inflammation, Necrosis, Eosinophilic Granuloma, Vasculitis, CTCAE, Systemic Vasculitis	Altered Intercellular Communication	A biopsy of the left peroneus brevis muscle showed active vasculitis with inflammation extending into muscle fascicles and fibrinoid necrosis of the vessel wall, consistent with eosinophilic granulomatosis with polyangiitis (EGPA).	27150880
Eosinophilic Granuloma, Systemic Vasculitis, Inappropriate ADH Syndrome	Altered Intercellular Communication	Syndrome of Inappropriate Antidiuretic Hormone Associated with Eosinophilic Granulomatosis with Polyangiitis.	27150880
Squamous cell carcinoma, Esophageal carcinoma	Altered Intercellular Communication	Inflammation-based prognostic system predicts postoperative survival of esophageal carcinoma patients with normal preoperative serum carcinoembryonic antigen and squamous cell carcinoma antigen levels.	27151090
Malignant Neoplasms	Altered Intercellular Communication	The Glasgow Prognostic Score (GPS) is an established inflammation-based system that is used to predict the prognosis for several types of malignancies.	27151090
Inflammation, multiorgan injury, Disease	Altered Intercellular Communication	Systemic inflammation has emerged as a key pathophysiological process that induces multiorgan injury and causes serious human diseases.	27151398
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Endothelium is critical in maintaining cellular and inflammatory homeostasis, controlling systemic inflammation, and progression of inflammatory diseases.	27151398
Inflammation, physiopathological	Altered Intercellular Communication	To identify endothelial cell-released soluble factors that protect against endothelial barrier dysfunction and systemic inflammation.	27151398
Inflammatory	Altered Intercellular Communication	Candida-associated denture stomatitis is an infectious inflammatory condition of the oral mucosa, with frequent recurrences.	27151707
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	CpG methylation at novel genes sheds light on new molecular pathways, which can be potentially exploited as a biomarker or targeted to attenuate inflammation and fibrosis.	27152124
Inflammation, Pancreatic carcinoma	Altered Intercellular Communication	A novel systemic inflammation response index (SIRI) for predicting the survival of patients with pancreatic cancer after chemotherapy.	27152949
Inflammation, Diabetic foot ulcer	Altered Intercellular Communication	Studies have emerged to demonstrate bidirectional changes in circulating cytokines of inflammation in active diabetic foot ulcers (DFU).	27153203
Inflammation, Colorectal Carcinoma, Neoplasms	Altered Intercellular Communication	Colorectal cancer (CRC) is one of the most common solid tumors worldwide, often associated with inflammation.	27153562
Colorectal Carcinoma	Altered Intercellular Communication	The microbes in the human intestine have a key role in inflammations and CRC.	27153562
chitotriose	Altered Intercellular Communication	Chitotriose renders growth advantage to some bacteria, especially some pathogens, and thus has a role in inflammations.	27153562
Epilepsy	Altered Intercellular Communication	Glutamate transporters manage glutamate levels and excitatory neurotransmission, and they have been associated with both epilepsy and TBI.	27153812
Inflammation, Skeletal muscle structure, Demographics Domain, Dermatomyositis, Disease	Altered Intercellular Communication	Dermatomyositis (DM) is a polygenic disorder characterized by inflammation of skeletal muscle and skin.	27153935
Airway structure, Asthma	Altered Intercellular Communication	Expression of miR-223-3p, miR-142-3p, and miR-629-3p is increased in sputum of patients with severe asthma and is linked to neutrophilic airway inflammation, suggesting that these miRNAs contribute to this asthma inflammatory phenotype.	27155035
Inflammation, Traumatic injury	Altered Intercellular Communication	Increased plasma nesfatin-1 concentrations are associated closely with inflammation, trauma severity and clinical outcomes, indicating that nesfatin-1 might be involved in inflammation and become a good prognostic biomarker following TBI.	27155585
Airway structure, SFC (Brand Name)	Altered Intercellular Communication	The use of SFC step-down resulted in somewhat better respiratory function, with no worsening of airway inflammation.	27155753
Inflammation	Altered Intercellular Communication	Adventitial inflammation was increased in CA IX-positive samples as compared with CA IX-negative ones (p < 0.01).	27157093
APP gene, Inflammation	Altered Intercellular Communication	This study demonstrates differential expression of transcripts in peripheral blood of individuals with AAA, with functional roles in proteolysis, inflammation, and apoptotic processes.	27157464
Intraocular inflammation, Uveitis	Altered Intercellular Communication	Uveitis is an intraocular inflammation affecting the highly vascularized uveal tissue.	27159029
Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Immune Inflammation and Disease Progression in Idiopathic Pulmonary Fibrosis.	27159038
Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	In conclusion an innate and adaptive inflammation appears to be a prominent feature in the lung of patients with IPF and could contribute to determining of the rate of disease progression.	27159038
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Activating transcription factor 3 (Atf3) has been implicated in the pathogenesis of various diseases, including cancer and inflammation, as well as in the regulation of cell proliferation and differentiation.	27159257
Inflammation, Foreign-Body Reaction	Altered Intercellular Communication	Histologic examination of the failed graft revealed skin with surface ulceration, focal abscess formation, deep penetrating acute and chronic inflammation with numerous eosinophils, and granulomatous changes demonstrating a foreign body-type reaction to fungal hyphae (highlighted by periodic acid-Schiff staining, Figures 1A-E).	27159513
vascular inflammations, Fibrosis Assessment	Altered Intercellular Communication	The profibrotic mediator Galectin-3 (Gal-3) has been associated with aldosterone-mediated vascular inflammation, fibrosis, and stiffness.	27159890
Airway structure, Asthma	Altered Intercellular Communication	A key therapeutic approach to asthma, which is characterized by chronic airway inflammation, is inhaled corticosteroid (ICS).	27160342
Airway structure, Symptoms	Altered Intercellular Communication	BHR to AMP may better reflect the relationship between improved airway inflammation due to ICS treatment and asthma symptoms.	27160342
Hyperplastic Polyp, Waldenstrom Macroglobulinemia	Altered Intercellular Communication	Compared with the hyperplastic polyps that lack the organisms, H pylori associated hyperplastic polyps more commonly had dense lymphoplasmacytic inflammation (P = .0001) and neutrophils within gastric epithelium (P = .036).	27160432
Acute Lung Injury, Inflammation	Altered Intercellular Communication	Acute lung injury (ALI) is characterized by rapid induction of inflammation at the alveolar-capillary membrane, and immunosuppressive mechanisms were shown to contribute to its resolution.	27161112
Inflammation, Ectogenesis, Epilepsy	Altered Intercellular Communication	Inflammation may be involved in the ictogenesis and development of some partial epilepsies.	27161531
Inflammation	Altered Intercellular Communication	Neutrophil-mediated inflammation may be important in the aetiopathogenesis of CSE.	27161531
Tremor	Altered Intercellular Communication	Mechanisms underlying VPA-induced tremors may involve abnormalities of DA and NE neurotransmitters.	27161592
Chronic Obstructive Airway Disease	Altered Intercellular Communication	Sarcopenic Obesity, Functional Outcomes, and Systemic Inflammation in Patients With Chronic Obstructive Pulmonary Disease.	27161848
Inflammation, Cardiac Hypertrophy	Altered Intercellular Communication	Recent studies have suggested that serum uric acid (SUA) induces oxidative stress and inflammation, which are involved in the mechanism of cardiac hypertrophy.	27162100
Inflammation, Arterial aneurysm, Intestinal necrosis	Altered Intercellular Communication	Mesenteric lesions involved intense arterial remodeling, progressive inflammation, occluded lumens, and less frequently intestinal necrosis and multiple visceral arterial aneurysms.	27162120
Atheroma, Atherosclerosis	Altered Intercellular Communication	Imaging Intraplaque Inflammation in Carotid Atherosclerosis With 18F-Fluorocholine Positron Emission Tomography-Computed Tomography: Prospective Study on Vulnerable Atheroma With Immunohistochemical Validation.	27162131
Atheroma	Altered Intercellular Communication	We hypothesized that (18)F-FCH could similarly be a valuable imaging tool to identify vulnerable plaques and associated intraplaque inflammation and atheroma cell proliferation.	27162131
Chronic tubulointerstitial nephritis, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Inflammation in Early Kidney Allograft Surveillance Biopsies With and Without Associated Tubulointerstitial Chronic Damage as a Predictor of Fibrosis Progression and Development of De Novo Donor Specific Antibodies.	27163535
Inflammation, Fibrosis Assessment, Tubular atrophy, Interstitial inflammation	Altered Intercellular Communication	Interstitial fibrosis and tubular atrophy (IFTA) associated with interstitial inflammation in nonscarred areas (IFTA+i) is associated with poorer graft outcome than inflammation without IFTA or IFTA without inflammation.	27163535
Inflammation	Altered Intercellular Communication	The histological diagnosis at 6 weeks was: normal (n = 206), inflammation (n = 29), IFTA (n = 255), and IFTA+i (n = 108).	27163535
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Moderate/severe interstitial fibrosis (ci>=2) at 1 year was observed in 4.2% of patients with prior (6 weeks) normal histology, in 3.4% with inflammation, in 13.8% with IFTA, and in 24.5% with IFTA+i (P = 0.0001).	27163535
Chronic tubulointerstitial nephritis, Inflammation	Altered Intercellular Communication	Early subclinical inflammation in surveillance biopsies with or without tubulointerstitial chronic lesions is associated with an increased risk of dnDSA development.	27163535
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Amylin from humans (but not rodents) has an increased propensity to aggregate into pancreatic islet amyloid deposits that contribute to b-cell mass depletion and development of type-2 diabetes by inducing oxidative stress and inflammation.	27163815
Celiac Disease, Inflammation, Hypertransaminasaemia, immunoglobulin A	Altered Intercellular Communication	According to ESPGHAN guidelines the finding of hypertransaminasemia as sign of celiac hepatic inflammation, a more than 10-fold increase of tTG IgA and a high-risk HLA would permit diagnosis of celiac disease but histological examination done due to mismatch between paucity of clinical sings and a "multiple risk combination" excluded it, allowing diagnosis of potential celiac disease.	27163902
Gastrointestinal inflammation	Altered Intercellular Communication	Upon recovery, fecal calprotectin, a marker of intestinal inflammation, was lower.	27163928
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	As observed in cancer immunotherapy, MDSCs could be a novel component in multimodality immunotherapy targeting detrimental inflammation and immunosuppression after SS/SS to improve currently observed dismal long-term outcomes.	27163951
Retinal Vasculitis, Vitreous inflammatory cells	Altered Intercellular Communication	Vision improved to 20/20 1 month postoperatively with complete resolution of vitreous inflammation and retinal vasculitis.	27164507
Pain Distress Question, vascular inflammations, Arthritis	Altered Intercellular Communication	Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation.	27165180
Inflammation	Altered Intercellular Communication	A role for TRPC5 in inflammation has not been previously shown in vivo.	27165180
Inflammation, Hyperalgesia	Altered Intercellular Communication	Genetic deletion or pharmacological blockade of TRPC5 results in an enhancement in joint inflammation and hyperalgesia.	27165180
Rheumatoid Arthritis	Altered Intercellular Communication	Fibroblast-like synoviocytes (FLS) in rheumatoid arthritis (RA-FLS) contribute to joint inflammation and damage characteristic of the disease.	27165430
Psoriatic Juvenile Idiopathic Arthritis, Inflammation, Psoriasis	Altered Intercellular Communication	Lipocalin-2 might be a marker of psoriasis and convey cardiovascular or metabolic risk in psoriatic patients, but may not be a reliable indicator of inflammation, severity of psoriasis nor efficacy of antipsoriatic treatment.	27165470
Inflammation, Traumatic injury	Altered Intercellular Communication	He had no noteworthy medical or family history, and was not aware of any history of trauma or inflammation in his head or neck area.	27165640
Communicable Diseases, Inflammation	Altered Intercellular Communication	We administered antibiotics and non-steroidal anti-inflammatory drugs because we suspected that his symptoms were the result of inflammation caused by an infection.	27165640
Inflammation, chronic inflammatory response	Altered Intercellular Communication	HLA-DR/DQ testing revealed a multisusceptible haplotype for development of chronic inflammation, and serum chronic inflammatory response syndrome (CIRS) biomarker testing was positive for highly elevated TGF-beta and a clinically undetectable level of vasoactive intestinal peptide (VIP).	27165859
Inflammation, Coronary Artery Disease, Collagen Diseases	Altered Intercellular Communication	Rheumatologic disorders are characterised by inflammation and an increased risk of coronary artery disease (CAD).	27166320
Inflammation, Antiphospholipid Antibodies, Lupus Erythematosus, Systemic, Corneal Endothelial Cell Loss	Altered Intercellular Communication	Changes to fibrinolysis in patients with systemic lupus erythematosus are associated with endothelial cell damage and inflammation, but not antiphospholipid antibodies.	27167859
Inflammation, Lupus Erythematosus, Systemic, Antiphospholipid Antibodies, ATRICHIA WITH PAPULAR LESIONS, Lupus Erythematosus	Altered Intercellular Communication	We investigated whether changes to fibrinolysis were associated with other manifestations of systemic lupus erythematosus (SLE), including antiphospholipid (APL) antibody status, endothelial damage, and inflammation.	27167859
Inflammation, Lupus Erythematosus, Systemic, Corneal Endothelial Cell Loss	Altered Intercellular Communication	This study has demonstrated that fibrinolysis is significantly altered in patients with SLE compared to controls, and associated with endothelial cell damage and inflammation, but not APL antibody status.	27167859
Kidney Failure, Acute	Altered Intercellular Communication	Generally AKI is not induced by MCNS in youth, but it may occur under severe inflammatory conditions.	27169260
Inflammation, Ochronosis, Autosomal Recessive Disorder, Calcinosis, Alkaptonuria	Altered Intercellular Communication	Alkaptonuria, or ochronosis, a rare autosomal recessive metabolic disorder, causes an excess of homogentisic acid that results in dark pigmentation, calcification, and inflammation of cartilaginous and other tissues.	27169295
Inflammation	Altered Intercellular Communication	Inflammation may contribute to an increase in cardiac wall stress through pathways related to cardiac remodeling.	27169396
Inflammation, Myocytes, Cardiac	Altered Intercellular Communication	We sought to explore associations among cardiac remodeling, inflammation and myocardial cell injury in a bi-ethnic cohort of South African men and women.	27169396
Inflammation, Heart Ventricle	Altered Intercellular Communication	The susceptibility for cardiac wall remodeling appears to increase with hyperpulsatile pressure, low-grade systemic inflammation and ventricular stress, and may lead to the development of future cardiovascular events in African men.	27169396
Inflammation, Endothelial dysfunction, Atherosclerosis, Erectile dysfunction	Altered Intercellular Communication	Chronic inflammation may cause endothelial dysfunction and atherosclerosis, resulting in subsequent erectile dysfunction (ED).	27169492
Inflammation, Communicable Diseases, Local-Regional anatomy, Cacosmia Plant, Headache	Altered Intercellular Communication	The clinical signs of infection were: headache, locoregional pain, cacosmia, inflammation of the oral buccal mucosa and rhinorrhea or unilateral nasal discharge.	27169511
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Low vitamin B-6 status has been related to increased risk of coronary artery disease (CAD), which is a condition that is associated with inflammation.	27169836
Inflammation, Non-alcoholic Fatty Liver Disease, Prediabetes syndrome	Altered Intercellular Communication	Subclinical inflammation in relation to insulin resistance in prediabetic subjects with nonalcoholic fatty liver disease.	27169860
Metabolic Diseases, Non-alcoholic Fatty Liver Disease, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Nonalcoholic fatty liver disease (NAFLD) is a metabolic disease commonly associated with obesity, type 2 diabetes, and inflammation-all features of insulin resistant syndrome.	27169860
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	However, very limited data are available regarding the association of subclinical inflammation and insulin resistance with NAFLD in a prediabetic state.	27169860
Inflammation, Non-alcoholic Fatty Liver Disease, Prediabetes syndrome	Altered Intercellular Communication	Subclinical chronic inflammation and insulin resistance seem to be independent mediators of the association between NAFLD and prediabetes.	27169860
Dyslipidemias, Prediabetes syndrome	Altered Intercellular Communication	The data also indicate that the inflammatory condition and insulin resistance are associated with each other and these, in turn, are affected by adiposity and dyslipidemia in prediabetic subjects.	27169860
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor alpha (TNF-a), a multifunctional cytokine, is involved in apoptosis, cell proliferation, cell survival, and inflammation.	27170003
Inflammation	Altered Intercellular Communication	This process is mainly driven by chronic inflammation and an altered activity of a multitude of different chemokines and cytokines, resulting in the infiltration by immune cells (especially macrophages) and increase of matrix-expressing cell types.	27170396
Inflammation, Brain Damage, Chronic	Altered Intercellular Communication	The hepatic capacity to remodel scar tissue and to revert into a normal liver follows specific mechanistic principles that include the termination of chronic tissue damage, shifting the cellular bias from inflammation to resolution, initiation of myofibroblast apoptosis or senescence and, finally, fibrinolysis of excess scar tissue.	27170396
Inflammation	Altered Intercellular Communication	Another target is galectin-3 that acts at various stages along the continuum from acute to chronic inflammation.	27170396
methyldopa, vascular inflammations	Altered Intercellular Communication	Moreover, lipoprotein-associated phospholipase A2 activity, a marker of vascular inflammation, was decreased in AMD subjects (MD -24.1, p<0.01).	27171197
Bronchiectasis, Pulmonary Emphysema, Thickening of pleura, Calcinosis, Pneumonitis, Pneumonia, Interstitial	Altered Intercellular Communication	Preoperative chest CT was retrospectively reviewed to assess pleural thickening or calcification, pulmonary calcified nodules, active pulmonary inflammation, extent of emphysema, interstitial pneumonitis, and bronchiectasis in the operated thorax.	27171235
Calcinosis, Pneumonitis	Altered Intercellular Communication	Localized pleural thickening was found in 8 patients (6.5%), localized pleural calcification in 8 (6.5%), pulmonary calcified nodules in 28 (22.6%), and active pulmonary inflammation in 22 (17.7%).	27171235
allergic inflammation, Fever, CTCAE	Altered Intercellular Communication	Lower Tregs and increased SOCS3 in combined heterozygotes and minor allele homozygotes may be relevant for hay fever development, pointing towards dysbalanced immune regulation and insufficient control of allergic inflammation.	27171815
Inflammation, Thrombosis, Coronary Artery Disease	Altered Intercellular Communication	Involvement of soluble CD40 ligand (sCD40L) in thrombosis and inflammation on the context of coronary artery disease is currently being revised.	27172386
Inflammation, Primary malignant neoplasm, Cardiovascular event, Cessation of life, Cardiovascular system	Altered Intercellular Communication	Comparison of the Predictive Value of GlycA and Other Biomarkers of Inflammation for Total Death, Incident Cardiovascular Events, Noncardiovascular and Noncancer Inflammatory-Related Events, and Total Cancer Events.	27173011
Inflammation, Chronic Kidney Diseases, Cerebrovascular accident	Altered Intercellular Communication	There are hypotheses that novel non-traditional risk factors, like chronic inflammation and oxidative stress, are involved in chronic kidney disease, affecting the cerebral microvasculature that would in turn lead to stroke.	27173119
Inflammation, Herpes encephalitis	Altered Intercellular Communication	A study on viral CNS inflammation beyond herpes encephalitis.	27173398
Inflammation, Malignant neoplasm of gallbladder, Biliary calculi	Altered Intercellular Communication	Most gallbladder cancer (GBC) cases arise in the context of gallstones, which cause inflammation, but few gallstone patients develop GBC.	27173614
Biliary calculi	Altered Intercellular Communication	We explored inflammation/immune-related markers measured in bile and serum in GBC cases compared to gallstone patients to better understand how inflammatory patterns in these two conditions differ.	27173614
Inflammation, Biliary calculi	Altered Intercellular Communication	GBC is associated with inflammation above and beyond that generated by gallstones alone.	27173614
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	Telomere shortening in non-neoplastic mucosa was associated with chronic inflammation (P = 0.0018) and intestinal metaplasia (P < 0.0001).	27173780
Pneumonitis	Altered Intercellular Communication	Secondary outcomes included patient activation, prescribing, adherence, spirometry, lung inflammation and health service contacts after 12 weeks.	27173807
Inflammation, Hormone refractory prostate cancer	Altered Intercellular Communication	As an acute-phase protein synthesized in response to systemic inflammation, the C-reactive protein (CRP) has been shown to be an independent prognostic factor for patients with castration-resistant prostate cancer (CRPC).	27174032
Inflammation	Altered Intercellular Communication	Our data suggest that both low and high birth weights are associated with greater visceral adiposity and biomarkers implicated in insulin resistance and inflammation in adolescents.	27174144
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	In addition to its classical endocrine character known for hemodynamic regulation, the renin-angiotensin system (RAS) can be associated with inflammation, wound healing, and cancer.	27174460
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Influences on plasminogen activator inhibitor-2 polymorphism-associated recurrent cardiovascular disease risk in patients with high HDL cholesterol and inflammation.	27174532
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	To investigate this issue, we have studied a group of post-myocardial infarction patients with high levels of C-reactive protein as an indicator of chronic inflammation and with concurrently high levels of HDL cholesterol.	27174532
Inflammation, emotional dependency	Altered Intercellular Communication	These included racial dependency, platelet clot initiation and propagation, oxidative stress, inflammation effects on HDL metabolism and coagulation, and induction and termination of fibrinolysis.	27174532
Airway structure, MS4A2 wt Allele	Altered Intercellular Communication	In the active asthma model, the percentage of mediation was 28.6% for pulmonary function, 18.1% for atopy and 5.7% for airway inflammation.	27174886
Fibrosis Assessment, Interstitial inflammation, Neoplasms	Altered Intercellular Communication	The reasons for frozen section errors and deferrals included larger tumour volume, tumour located close to the visceral pleura, interstitial inflammation or fibrosis, absence of prominent atypia and differential morphology in the deeper levels of the paraffin block.	27174927
Inflammation, Fever, CTCAE, Exacerbation of cGVHD	Altered Intercellular Communication	Fever at diagnosis and severity of inflammation at TAB appear to predict the development of disease flares.	27175649
APP gene, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Although the precise mechanisms underlying the pathogenesis of abdominal aortic aneurysm (AAA) remain unclear, aortic wall inflammation has been implicated in AAA development.	27175690
Rupture	Altered Intercellular Communication	The scans revealed chronological changes in aortic wall inflammation leading to progress and eventual rupture.This case supports a notion that aortic wall inflammation plays a role in AAA progression and rupture.	27175690
Gingivitis, VWF wt Allele, Gingival Hemorrhage, von Willebrand Disease, Type 3	Altered Intercellular Communication	Gingival bleeding in VWD patients may be triggered by gingival inflammation, but it is not a genuine symptom of mild type 1 VWD.	27177144
Inflammation, Toxic effect	Altered Intercellular Communication	Aerosol IL-2 selectively increased infiltration, retention, and proliferation of infused NK cells in the lung, and there was no local inflammation or toxicity in the lungs or any other organ.	27177675
Varices of ovary, Endometriosis	Altered Intercellular Communication	Ovarian varices may evolve with oxidative stress in the function of the ovary, provoking an imbalance in its genetic, hormonal, and immunologic aspects and provoking the chronic inflammatory process particular to endometriosis.	27177709
Inflammation, FAM126A gene	Altered Intercellular Communication	Survivin deficiency results in mitosis defect-associated senescence in HCC cells, which triggers local inflammation and increased TNFa.	27177758
Cholecystitis	Altered Intercellular Communication	Surgical outcomes depend among other factors on the extent of gallbladder inflammation.	27177953
Inflammation, Sleep Disorders	Altered Intercellular Communication	Sleep disorders (SDs), particularly sleep deprivation, may alter the immune system and induce systemic inflammation.	27178314
RANGAP1 wt Allele, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	SD individuals with moderate-to-high gingival inflammation showed a significantly increased risk of cardiovascular disease (1.39 [1.04-1.84]) compared to SD individuals with low or no gingival inflammation.	27178314
Gingivitis	Altered Intercellular Communication	Individuals with self-report SDs are at increased risk of gingival inflammation.	27178314
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The coexistence of SDs and gingival inflammation is associated with an increased risk of cardiovascular diseases.	27178314
Airway structure, Asthma	Altered Intercellular Communication	Periostin may be a useful biomarker of T-helper type 2 eosinophilic airway inflammation and has been linked to remodeling in asthma.	27178891
Inflammation, Asthma	Altered Intercellular Communication	Serum periostin may be a candidate for a novel biomarker for not only eosinophilic inflammation but as a marker for airway remodeling in asthma.	27178891
Inflammation	Altered Intercellular Communication	Re-transfusion of lipid particles and activated leucocytes with shed mediastinal blood (SMB) can aggravate cardiopulmonary bypass-associated inflammation and increase the embolic load.	27178989
Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation biomarkers and mortality prediction in patients with type 2 diabetes (ZODIAC-27).	27179179
Inflammation, Venous stasis, International Classification of Disease, Ninth Revision	Altered Intercellular Communication	The National Inpatient Sample was queried to identify all Caucasian and African-American patients with a primary International Classification of Diseases, Ninth Revision (ICD-9) diagnosis code for venous stasis with ulceration (454.0), inflammation (454.1), or complications (454.2) from 1998 to 2011.	27179983
Communicable Diseases, vascular inflammations	Altered Intercellular Communication	Although interferon (IFN)-g-induced protein 10 (IP-10)/CXCL10 is induced during vascular inflammation, data on CXCL10 in R. conorii infection is scarce.	27180202
Inflammation	Altered Intercellular Communication	Two had histological features of chronic non specific inflammation.	27180374
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Epigenetics is now considered to be crucially involved in normal genetics and differentiation and in pathological conditions, such as cancer, aging, and inflammation.	27180790
Inflammation	Altered Intercellular Communication	Our results suggest that epigenetic changes participate in chronic inflammation and aging in the palatine tonsils.	27180790
Inflammation, Infection, Kidney Diseases	Altered Intercellular Communication	Although the results do not lead to a direct treatment, the epigenetic pathogenesis of chronic inflammation, such as immunoglobulin A nephropathy, by focal infections will be described in greater detail in future studies, which will lead to new treatments being developed.	27180790
Inflammation, Acne, Synovitis, Osteitis, Sapho, Hyperostosis, Pustulosis of Palms and Soles	Altered Intercellular Communication	In consideration of subcutaneous humps in the sterno-clavicular area and palmoplantar pustulosis, we diagnosed him as having synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome and speculated that it induced peri-osteal chronic inflammation in the sterno-clavicular area, resulting in occlusion of the adjacent bilateral subclavian veins.	27181039
Inflammation, Inflammatory disorder	Altered Intercellular Communication	T cell immunoglobulin and mucin domain-containing molecule 3 (Tim-3) has been reported as an important regulatory inflammation molecule, and plays a pivotal role in several inflammation-related diseases.	27182056
Diabetes Mellitus, Non-Insulin-Dependent, Disease	Altered Intercellular Communication	Obesity-associated insulin resistance in type 2 diabetes is a disorder in the balance between pro-inflammatory and anti-inflammatory signals.	27182056
Inflammation, Hepatobiliary Disorder, Fibrosis Assessment	Altered Intercellular Communication	Significant predictors of liver disease (stage >=2 fibrosis or stage 1 fibrosis plus grade >=2 inflammation), including demographic, clinical, and laboratory variables, were evaluated by means of univariate and multivariate logistic regression analyses.	27182648
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Among the patients, 75.5% (77/102) had grade 0-1 inflammation and 77.5% (79/102) had stage 0-1 fibrosis.	27182648
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Lately, low-grade inflammation is recognized as accompanying obesity, a known risk factor for type 2 diabetes.	27182718
Inflammation, Autonomic nervous system disorders	Altered Intercellular Communication	Chronic low-grade inflammation, insulin resistance, and autonomic dysfunction are present at an early age in obese youths; early detection of inflammation may facilitate meaningful lifestyle changes in this high-risk group.	27182718
Vascular Diseases	Altered Intercellular Communication	Furthermore, the high frequency of the small-vessel stroke subtype in AS patients indicates that small-vessel inflammation may be involved in the pathogenesis of vascular diseases in AS patients.	27182728
TNF protein, human, Airway structure	Altered Intercellular Communication	Hyperoxia-exposed RV-infected mice showed further increases in IL-12 and increased expression of IFN-g, TNF-a, CCL2, CCL3, and CCL4, as well as increased airway inflammation and responsiveness.	27183577
Inflammation, Respiratory Hypersensitivity, Hyperoxia, Residual volume	Altered Intercellular Communication	Hyperoxic exposure increases the activation of CD103(+), Clec9a(+) DCs, leading to increased inflammation and airway hyperresponsiveness upon RV infection.	27183577
Communicable Diseases, Inflammation, Venous Engorgement	Altered Intercellular Communication	The underlying etiology may be inflammation, infection, and associated venous congestion within the spinal canal.	27184560
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	However, further exploration of areas regarding therapeutic strategy might be possible to support metabolic activity, decrease inflammation, or enhance regeneration for liver cirrhosis.	27185598
Hemorrhage, Urethritis	Altered Intercellular Communication	Cystoscopy was done in all patients which revealed bulbar urethral inflammation and hemorrhage in all.	27186701
Inflammation, Destruction (action)	Altered Intercellular Communication	The mechanism underlying the CNS pathology causing sequelae in TBE appears related to the grade of inflammation in CNS, rather than to direct neuronal destruction.	27187756
Aggressive Periodontitis	Altered Intercellular Communication	Gingival Inflammation and Aggressive Periodontitis in a Child with a Specific Antibody Deficiency.	27188128
Inflammation, Periodontitis	Altered Intercellular Communication	Exuberant gingival inflammation accompanied by periodontitis is a rare finding in a very young child and may indicate a defect in the host response.	27188128
Inflammation, Periodontal Route of Administration	Altered Intercellular Communication	A 5-year-old girl presented with persistent gingival inflammation and periodontal destruction.	27188128
Inflammation, Periodontitis	Altered Intercellular Communication	CPD/Clinical Relevance: This article describes a rare case of gingival inflammation accompanied by periodontitis in a very young child secondary to an underlying host antibody deficiency and details the investigation, management and clinical outcomes.	27188128
Stomatitis, Inflammation, Exanthema	Altered Intercellular Communication	The most frequent grade 3 adverse events were rash (59%), mucosal inflammation (26%), and stomatitis (18%).	27188206
Pancreatitis	Altered Intercellular Communication	They may be seen in patients with pancreatic inflammation or pancreatitis.	27188399
Inflammation	Altered Intercellular Communication	Comparing the diagnosis and alterations in lichenoid and sclerotic patterns and in chronic inflammation, we found statistically significant differences.	27188744
Sepsis, Communicable Diseases	Altered Intercellular Communication	Sepsis was associated with a 22.1% (95% confidence interval 17.5% to 26.7%) absolute increase in late mortality relative to adults not in hospital, a 10.4% (5.4% to 15.4%) absolute increase relative to patients admitted with non-sepsis infection, and a 16.2% (10.2% to 22.2%) absolute increase relative to patients admitted with sterile inflammatory conditions (P<0.001 for each comparison).	27189000
Inflammation, Fibrosis Assessment, Traumatic injury	Altered Intercellular Communication	Association of Urinary Biomarkers of Inflammation, Injury, and Fibrosis with Renal Function Decline: The ACCORD Trial.	27189318
Injury of gastrointestinal tract, Gastrointestinal inflammation	Altered Intercellular Communication	These findings suggest that dietary anemonin attenuates LPS-induced intestinal injury by improving mucosa restoration, alleviating intestinal inflammation and influencing TGF-b1 canonical Smads and EGFR signaling pathways.	27189428
Inflammation, Necrosis	Altered Intercellular Communication	Nevertheless, heart Fe in FA contributes to cardiomyocyte necrosis, inflammation, and scarring as the disease progresses.	27189813
Inflammatory Bowel Diseases, Inflammation, Psychologic, Somatization	Altered Intercellular Communication	Levels of psychological comorbidity and somatization were significantly higher among patients with true IBS-type symptoms than patients with quiescent IBD or occult inflammation.	27189912
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Macrophage migration inhibitor factor (MIF) is a pluripotent cytokine associated with several different inflammatory conditions, but its role within lung inflammation and chronic obstructive pulmonary disease (COPD) is unclear.	27190066
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Macrophage migration inhibitor factor (MIF) is a pluripotent cytokine associated with several different inflammatory conditions, but its role within lung inflammation and chronic obstructive pulmonary disease (COPD) is unclear.	27190066
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Central arterial stiffness is associated with systemic inflammation among Asians with type 2 diabetes.	27190079
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	To examine the relationship between inflammation and central arterial stiffness in a type 2 diabetes Asian cohort.	27190079
Arterial Stiffness, glycation, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Elevated high-sensitivity C-reactive protein and decreased soluble receptor for advanced glycation end products are associated with augmentation index and pulse wave velocity, respectively, suggesting the potential role of systemic inflammation in the pathogenesis of central arterial stiffness in type 2 diabetes.	27190079
Hereditary Autoinflammatory Diseases, Inflammation, Exanthema, Autosomal recessive inheritance, Cervical lymphadenopathy, Intermittent, Hyperimmunoglobulinemia D, Job Syndrome, Gastrointestinal symptom, Arthritis	Altered Intercellular Communication	Hyperimmunoglobulinaemia D syndrome (HIDS) is an autosomal recessive, autoinflammatory disease that is characterised with intermittent febrile episodes, cervical lymphadenopathy, rashes, arthritis and gastrointestinal symptoms associated with synovial or serosal inflammation.	27190114
Inflammation	Altered Intercellular Communication	While immunosuppression is the major determinant of poor outcomes during ART, baseline inflammation is an additional important factor, identifying a subgroup of young children with similar mortality.	27190179
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Genotypic and phenotypic predictors of inflammation in patients with chronic kidney disease.	27190335
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Here, it is applied to identify risk factors for inflammation in CKD.	27190335
Inflammation, Hereditary	Altered Intercellular Communication	These results indicate a larger involvement of hereditary factors in inflammation than might have been expected and suggest that inclusion of genotype features in risk assessment studies is critical.	27190335
Inflammation, Restless Legs Syndrome, Chronic Kidney Diseases	Altered Intercellular Communication	The RLS model demonstrates that inflammation in CKD is determined by an extensive panel of factors and may prove to be a suitable tool that could enable a much-needed multifactorial approach as opposed to the commonly utilized single-factor analysis.	27190335
Inflammation, Dyslipidemias, Chronic Kidney Diseases, Diabetes Mellitus	Altered Intercellular Communication	Diabetes, dyslipidaemia, inflammation and mineral-bone disorders play a role in the appearance of PAD in CKD.	27190385
Panuveitis, Ocular sarcoidosis, Skin structure of eyelid, Uveitis, conjunctiva, Orbital Pseudotumor	Altered Intercellular Communication	Ocular sarcoidosis was present in 32 patients (36.4% of all) and included: eyelid skin lesions (2.3%); orbital inflammation (2.3%); conjunctival lesions (7.9%); anterior uveitis (2.3%); intermediate uveitis (1.1%); posterior uveitis (15.9%); panuveitis (5.7%), and neuro-ophthalmologic manifestations (9.1%).	27191355
Inflammation, Dental Plaque	Altered Intercellular Communication	Consequently, ALDH2 gene silencing led to an increased en face plaque area, more unstable plaque with heavier accumulation of lipids, more macrophages, less smooth muscle cells and collagen, which were associated with aggravated inflammation.	27191745
Inflammation, Dental Plaque	Altered Intercellular Communication	These findings suggested that ALDH2 can influence plaque development and vulnerability, and inflammation via MAPK, NF-kB and AP-1 signaling pathways.	27191745
Refractory anemias, Inflammation, Erosion lesion, Rheumatoid Arthritis	Altered Intercellular Communication	The main aim of this study was to investigate the relationship between ultrasound (US) findings indicative of joint inflammation and US features characterising bone erosions at joint level in patients with rheumatoid arthritis (RA) in clinical remission.	27192221
Inflammation, Erosion lesion	Altered Intercellular Communication	An experienced sonographer blind to the clinical data performed the US examinations to detect and score signs of joint inflammation and bone erosions from second to fifth metacarpophalangeal (MCP) joints of both hands.	27192221
Refractory anemias, Inflammation, Erosion lesion	Altered Intercellular Communication	This is the first study providing evidence supporting the association between US bone erosions and the persistence of subclinical inflammation in RA patients in clinical remission.	27192221
melanoma, Inflammation, Neoplasms, Eczema	Altered Intercellular Communication	Case report of a 48-year-old woman with no significant medical history who first presented with an eczematous dermatitis on her torso, extremities, and buttocks and who subsequently developed thousands of pinpoint, histologically atypical melanocytic tumors and invasive melanoma within the areas of inflammation.	27192392
Carcinogenesis	Altered Intercellular Communication	In recent years, the relevance of the two diseases has drawn attention in terms of the close epidemiological connection and chronic inflammation-associated carcinogenesis.	27192776
Inflammation, Hyponatremia, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Our study firstly showed that hyponatremia could reflect a disease activity and severe inflammation of SLE.	27193532
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Cancer as a promoter of inflammation may be more likely to account for our findings than low-grade inflammation promoting cancer development.	27194008
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Recent efforts in osteoarthritis (OA) research have highlighted synovial inflammation and involvement of immune cells in disease onset and progression.	27194025
Inflammation, Nerve Degeneration	Altered Intercellular Communication	We do this by evaluating mRNA and protein (immunohistochemical) markers of regeneration, neurodegeneration, myogenesis, cell cycle regulation, and inflammation.	27195289
Infection, Chronic inflammation, Chronic otitis	Altered Intercellular Communication	Surgical site infections after chronic otitis media surgery seem to be associated with factors related to the inflammatory state of the middle ear at the time of surgery in early infections and with chronic inflammation in late infections.	27196077
Inflammation, Coronary heart disease	Altered Intercellular Communication	Chronic inflammation may promote development of coronary heart disease.	27196450
Cerebral Amyloid Angiopathy, Vasculitis, Inflammation	Altered Intercellular Communication	Imaging Findings of Cerebral Amyloid Angiopathy, Ab-Related Angiitis (ABRA), and Cerebral Amyloid Angiopathy-Related Inflammation: A Single-Institution 25-Year Experience.	27196463
Cerebral Amyloid Angiopathy, vascular inflammations	Altered Intercellular Communication	Vascular inflammation is present in a subset of patients with cerebral amyloid angiopathy (CAA) and has a major influence in determining the disease manifestations.	27196463
Vasculitis, vascular inflammations, Inflammation	Altered Intercellular Communication	Patients were grouped into CAA alone (no vascular inflammation), Ab-related angiitis or ABRA (angiodestructive inflammation), and CAA-related inflammation or CAA-RI (perivascular inflammation).	27196463
Inflammation, Hemorrhage	Altered Intercellular Communication	In conclusion, leptomeningeal enhancement and lobar hemorrhage at presentation may enable differentiation between CAA with and without inflammation.	27196463
Inflammation, Lymphoma	Altered Intercellular Communication	However, the SUVmax ratio of the spleen/bone marrow of the lymphoma patients was significantly different from that of the inflammation patients (t = 2.426, P = 0.021 < 0.05).	27196500
Inflammation, Fatty degeneration	Altered Intercellular Communication	In the nontumoral liver, significant steatosis (>=5% of hepatocytes) was generally present (in 10/11 patients), with mild lobular inflammation and absence of ballooning in most cases.	27196679
Malignant neoplasm of urinary bladder	Altered Intercellular Communication	We evaluated the association of SNPs in inflammation-related genes with non-muscle-invasive bladder cancer (NMIBC) risk-of-recurrence and risk-of-progression.	27197286
Excessive tearing, Blepharitis	Altered Intercellular Communication	Ocular discomfort occurred in 43 of 49 patients in the fluorouracil group versus 36 of 49 in the placebo group, epiphora occurred in 24 versus five, and eyelid skin inflammation occurred in seven versus none.	27198842
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Inflammation and platelets at the acute event do not forecast long-term survival of stroke sufferers.	27199199
Inflammation	Altered Intercellular Communication	Correlation of A2bAR and KLF4/KLF15 with Obesity-Dyslipidemia Induced Inflammation in Uygur Population.	27199507
Inflammation	Altered Intercellular Communication	In vitro modeling of COPD inflammation and limitation of p38 inhibitor - SB203580.	27199554
ARCN1 gene, Inflammation	Altered Intercellular Communication	Systemic inflammation and steroid resistance are the hallmarks of COPD.	27199554
ARCN1 gene, Inflammation	Altered Intercellular Communication	Inhibition of p38 phoshorylation had a limited effect in restoring impaired lymphocyte function and suppressing inflammation induced by COPD serum, implying important p38-independent inflammatory mechanisms in COPD.	27199554
Inflammation	Altered Intercellular Communication	While it presents as cutaneous inflammation with painful and erythematous nodules which demonstrate ulceration, imaging features of this pathology are seldom described.	27200166
Inflammation, Necrosis	Altered Intercellular Communication	MR imaging with its excellent soft tissue contrast can be helpful in confirming the diagnosis, demonstrating imaging features of fat necrosis with surrounding inflammation as demonstrated in our patient.	27200166
Inflammation	Altered Intercellular Communication	Endoscopic inflammatory features show a weak correlation with histopathology but should not replace histologic indices of inflammation.	27200524
Inflammation, Dermatitis	Altered Intercellular Communication	The results demonstrate that genetic variations in genes related to inflammation and skin homeostasis can influence responses to irritants and may explain inter-individual variation in the development of subsequent contact dermatitis.	27206134
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Systemic inflammation in patients with compromised upper airway anatomy and primary snoring or mild obstructive sleep apnea.	27207142
Inflammation, Airway Compromise, Sleep Apnea, Obstructive, Snoring	Altered Intercellular Communication	Systemic inflammation is strongly associated with average and lowest SpO2, RDI and AI (and with HI) in snorers with compromised upper airway anatomy and is present even in patients with primary snoring and mild obstructive sleep apnea.	27207142
nervous system disorder	Altered Intercellular Communication	Metabolic and inflammatory conditions may lead to neurological disorders.	27207447
vascular inflammations	Altered Intercellular Communication	In all subjects, it decreased vascular inflammation marker soluble intercellular adhesion molecule-1 (-10%, P < 0.01).	27207552
Exanthema, Leukocytosis, Fever, CTCAE, Arthralgia, Hyperferritinaemia, Juvenile-Onset Still Disease	Altered Intercellular Communication	Adult-onset Still's disease (AOSD) is a systemic inflammatory condition of unknown aetiology characterized by typical episodes of spiking fever, evanescent rash, arthralgia, leukocytosis and hyperferritinemia.	27207567
Inflammation, Cervical dysplasia	Altered Intercellular Communication	Decreased RARb expression induces abundant inflammation and cervical precancerous lesions.	27207583
Inflammation, Carcinogenesis	Altered Intercellular Communication	Importantly, our results suggest that the low expression of RARb, may induce the down regulation of p16(INK4a), chronic inflammation and decreased apoptosis and may be involved in vulnerability to HR-HPV and early stage cervical carcinogenesis.	27207583
Inflammation, Chronic sinusitis, Craniosynostosis, Acute and chronic inflammation	Altered Intercellular Communication	This work sampled four different anatomical regions within the human nasal passage across a large cohort of individuals (n = 79) comprising individuals suffering from chronic nasal inflammation clinically known as chronic rhinosinusitis (CRS) and individuals not suffering from inflammation (CRS-free).	27207744
Inflammation, Necrosis, Cardiovascular system	Altered Intercellular Communication	In patients with STEMI, a multimarker strategy that combines biomarkers across pathobiological axes of myocardial stress, myocyte necrosis, and inflammation provides incremental prognostic information for prediction of cardiovascular death or HF.	27207959
Inflammatory Bowel Diseases	Altered Intercellular Communication	Its pathogenesis remains largely unknown, although frequent concomitant IBD hints towards common factors underlying gut and bile duct inflammation.	27207975
Inflammation, Complications of Diabetes Mellitus, Cardiac Arrhythmia	Altered Intercellular Communication	A1C is associated with diabetes complications but does not reflect glycemic variability (GV), which may worsen outcomes by inducing inflammation, oxidative stress, and cardiac arrhythmias.	27208320
Inflammation, Venous Thromboembolism, Electrocardiogram: myocardial infarction (finding), Obesity, vinyltriethoxysilane	Altered Intercellular Communication	Background Low-grade inflammation in obesity may be a shared pathway for the risk of venous thromboembolism (VTE) and myocardial infarction (MI).	27208592
Inflammation, vinyltriethoxysilane, Obesity	Altered Intercellular Communication	Conclusions Our findings suggest that low-grade inflammation, assessed by measurement of CRP, is associated with the risks of MI and VTE, and may be a shared pathway for MI and VTE in obesity.	27208592
Airway structure, Signs and Symptoms, Respiratory, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Short-term exposure to high ambient air pollution increases airway inflammation and respiratory symptoms in chronic obstructive pulmonary disease patients in Beijing, China.	27209003
Refractory anemias, Inflammation	Altered Intercellular Communication	Arterial wall inflammation, bone marrow and splenic activity (index of progenitor cell activity) was assessed with (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography/computed tomography (PET/CT) in RA patients in remission (disease activity score (DAS28) <2.6 for >6 months) and healthy controls.	27209093
Refractory anemias	Altered Intercellular Communication	Overall, arterial wall inflammation was comparable in RA patients (n = 23) in long-term remission and controls (n = 17).	27209093
Disease, Arteritis	Altered Intercellular Communication	In these subjects, RA disease duration was the most important contributor to the level of arterial wall inflammation.	27209093
Inflammation, Experimental Organism Basal Cell Carcinoma, Neoplasms	Altered Intercellular Communication	The data analysis showed that inflammation in patients with basal cell carcinoma (BCC) positively correlated with advanced age (p < 0.01), tumor diameter (p < 0.05), and the appearance of ulceration (p < 0.001).	27209420
Aggressive course, Inflammation	Altered Intercellular Communication	The comparison between premalignant and malignant conditions showed that inflammation probability increases as we move toward the more aggressive tumor phenotypes.	27209420
Endocrine System Diseases, Neoplasms	Altered Intercellular Communication	Most reports have focused on the various hormonal combinations in double tumors rather than on any potential increased risk for residual mass or endocrinopathy.	27209585
Congenital bilateral aplasia of vas deferens	Altered Intercellular Communication	Rapamycin may alleviate inflammation-induced initiation and progression of CAVD.	27209607
Squamous cell carcinoma of esophagus	Altered Intercellular Communication	A Novel Inflammation-Based Stage (I Stage) in Patients with Resectable Esophageal Squamous Cell Carcinoma.	27212808
Squamous cell carcinoma of esophagus	Altered Intercellular Communication	In the current study, we proposed a novel inflammation-based stage, named I stage, for patients with resectable esophageal squamous cell carcinoma (ESCC).	27212808
Squamous cell carcinoma of esophagus	Altered Intercellular Communication	The inflammation-based stage (I stage) is a novel and useful predictive factor for CSS in patients with resectable ESCC.	27212808
Inflammation, Superficial ulcer	Altered Intercellular Communication	Magnetic Resonance Imaging-Detected Features of Inflammation and Erosions in Symptom-Free Persons From the General Population.	27213695
Inflammation, Damage, Rheumatoid Arthritis	Altered Intercellular Communication	The use of magnetic resonance imaging (MRI)-detected inflammation and joint damage in the diagnosis of rheumatoid arthritis is recommended by a European League Against Rheumatism imaging task force.	27213695
Inflammation	Altered Intercellular Communication	For analyses at the joint level, MRI-detected inflammation was considered present if both readers scored the image as positive.	27213695
Inflammation, Superficial ulcer	Altered Intercellular Communication	MRI-detected inflammation and erosions are prevalent in symptom-free persons from the general population, especially at older ages and at preferential locations.	27213695
Inflammation, Uveitis, Intermediate	Altered Intercellular Communication	The new combination surgery for wet age-related macular degeneration and concurrent chronic peripheral uveitis provides rapid reduction of inflammation in the extreme periphery of the fundus and a 1.5 times faster (as compared to traditional methods) primary restoration of topographic anatomy of the retina in the macular region.	27213803
Inflammation	Altered Intercellular Communication	Evaluation of a novel point-of-care test for active matrix metalloproteinase-8: agreement between qualitative and quantitative measurements and relation to periodontal inflammation.	27214099
Inflammation, Dental Plaque	Altered Intercellular Communication	Beside clinical variables for plaque and inflammation, aMMP-8 concentrations were determined in oral rinsing specimens by the enzyme-linked immunosorbent assay (ELISA) and by POC.	27214099
Inflammation, Dental Plaque	Altered Intercellular Communication	Patients who had positive aMMP-8 test results (POC) showed higher scores for plaque and inflammation.	27214099
Respiratory physiology, Pomalidomide-Cyclophosphamide-Dexamethasone Regimen, Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus, Pneumonitis	Altered Intercellular Communication	Primary Cilia Dyskinesia (PCD) is a rare, genetically heterogeneous disease that causes chronic pulmonary inflammation and progressive loss of lung function due to the dysfunction of cilia.	27214451
Inflammation, Psoriasis, Obesity, Chronic inflammatory disorder	Altered Intercellular Communication	Since obesity is associated with increased and/or delayed resolution of inflammation observed in various chronic inflammatory diseases such as psoriasis, we investigated the impact of FFAs on human monocyte-derived and mouse bone marrow-derived dendritic cell (DCs) functions relevant for the pathogenesis of chronic inflammation.	27214608
Obesity	Altered Intercellular Communication	Interestingly, obesity in mice worsened a TH1/TH17-driven psoriasis-like skin inflammation.	27214608
Degenerative polyarthritis, Dermatitis	Altered Intercellular Communication	Strong correlation of the amount of total FFA, PA, and OA in serum with the severity of skin inflammation points to a critical role of FFA in obesity-mediated exacerbation of skin inflammation.	27214608
Inflammation, Psoriasis	Altered Intercellular Communication	Our data suggest that increased levels of FFAs might be a predisposing factor promoting a TH1/TH17-mediated inflammation such as psoriasis in response to an inflammatory danger signal.	27214608
Inflammation	Altered Intercellular Communication	Association Between Genetic Variation in FOXO3 and Reductions in Inflammation and Disease Activity in Inflammatory Polyarthritis.	27214848
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Genetic variation in FOXO3 (tagged by rs12212067) has been associated with a milder course of rheumatoid arthritis (RA) and shown to limit monocyte-driven inflammation through a transforming growth factor b1-dependent pathway.	27214848
Refractory anemias, Inflammation	Altered Intercellular Communication	Similarly, rs12212067 (a single-nucleotide polymorphism that increases FOXO3 transcription) was associated with reduced inflammation, both biochemically and clinically, and with lower RA activity scores.	27214848
Refractory anemias, Inflammation, Arthritis	Altered Intercellular Communication	Consistent with its known role in restraining inflammatory responses, FOXO3 limits the severity of in vivo arthritis and, through genetic variation that increases its transcription, is associated with reduced inflammation and disease activity in RA patients, effects that result in less radiographic damage.	27214848
Anemia	Altered Intercellular Communication	The Hema-Plot illustrated the dynamic character of Ret-He and Delta-He, notably in inflammation-based types of anemia like ACD or ACD/ IDA.	27215087
Inflammation, Friedreich Ataxia	Altered Intercellular Communication	For the first time in a genetic condition, we have also shown a disease-related increase in the frequency of Purkinje cell fusion and heterokaryon formation in Friedreich's ataxia cases; with evidence that underlying levels of cerebellar inflammation influence heterokaryon formation.	27215193
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	A possible association between mucosal immunization and inflammation, as well as the initiation and propagation of rheumatoid arthritis (RA), is attracting renewed interest.	27215344
Airway structure	Altered Intercellular Communication	However, the role of the alarmin protein high-mobility group box 1 (HMGB1) in upper airway inflammation is unclear.	27216346
Airway structure	Altered Intercellular Communication	To determine if HMGB1 is present in the nasal mucosa and, if so, to elucidate its role in upper airway inflammation.	27216346
Airway structure	Altered Intercellular Communication	TNF-a stimulates the production of HMGB1, which, in turn, upregulates the production and secretion of IL-6 and IL-8 by nasal epithelial cells via toll-like receptor 4, which indicated that HMGB1 plays an important role in the pathogenesis of upper airway inflammation.	27216346
Rickettsia conorii, vascular inflammations, Boutonneuse Fever	Altered Intercellular Communication	Mediterranean spotted fever caused by Rickettsia conorii is a potentially lethal disease characterized by vascular inflammation affecting multiple organs.	27217049
Inflammation, Cartilage damage, Pain Distress Question	Altered Intercellular Communication	It leads to cartilage damage associated with subchondral bone changes and synovial inflammation, causing pain and disability.	27217345
Inflammation	Altered Intercellular Communication	These proteins are involved in inflammation, immune as well as in the proteasome activation occurring in situations of endoplasmic reticulum stress.	27217411
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Abnormal olfaction is common with chronic rhinosinusitis (CRS) and associates with various measures of sinonasal inflammation.	27218483
Inflammation, Aortitis	Altered Intercellular Communication	The higher frequency of active aortitis in patients with dissection suggests that active inflammation may play a role.	27219304
Inflammation, Arthritis	Altered Intercellular Communication	There was a brief period of migratory arthritis, followed by persistent, severe inflammation in 1 knee.	27219308
Cyst, Inflammation	Altered Intercellular Communication	The most common benign diagnoses were cysts (33%) and inflammation (22%).	27220040
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Fecal Human Neutrophil Peptide Levels Correlate with Intestinal Inflammation in Ulcerative Colitis.	27220673
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Fecal markers have recently been found to provide convenient and noninvasive assessment of intestinal inflammation in inflammatory bowel disease (IBD).	27220673
Inflammation, Cardiac complication	Altered Intercellular Communication	Inflammation is a common feature in dialysis patients and is associated with cardiovascular complications and poor outcome.	27220753
Inflammation	Altered Intercellular Communication	Measuring the variability of inflammatory markers may help in understanding underlying factors triggering inflammation.	27220753
palladium, HD Term Type, Inflammation	Altered Intercellular Communication	Here we explored factors associated with the magnitude and variability of inflammation markers in HD and PD patients.	27220753
Inflammation, Comorbidity	Altered Intercellular Communication	Information on comorbidity, protein-energy wasting (PEW) and medications was gathered at baseline, and information on symptoms potentially related to inflammation was gathered weekly.	27220753
Inflammation	Altered Intercellular Communication	PEW predicted increased inflammation variability after correcting for age, sex, dialysis vintage, modality and comorbidity.	27220753
Parkinson Disease, Inflammation, palladium	Altered Intercellular Communication	There is evidence for a relevant role of inflammation in the pathogenesis of Parkinson's disease (PD).	27220776
palladium, Unknown (origin) (qualifier value), Inflammation	Altered Intercellular Communication	Concomitant inflammation seems to be associated with idiopathic and LRRK2-associated PD.	27220776
Inflammation, Periodontitis	Altered Intercellular Communication	The prevalence of TTMV-222 in the periodontitis group (n = 150) was significantly higher than that in the healthy group (n = 150) (p = 0.032), suggesting that the new virus may be associated with inflammation in chronic periodontitis patients.	27221159
Intravascular thrombosis, Acute pulmonary embolism, Inflammation, APEX1 protein, human	Altered Intercellular Communication	In some patients, the disease is preceded by acute pulmonary embolism (APE), and is characterised by intravascular thrombosis, vasoconstriction, inflammation and remodelling of pulmonary arteries.	27221958
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Exclusion criteria included malignancy, inflammation, and recent operation.	27221958
Inflammation, muscle mass	Altered Intercellular Communication	Our results suggested that major contributing factors to PEW were reduced muscle mass, unintentional low dietary energy intake, lower amount of exercise, insulin resistance, and chronic inflammation.	27222412
Hyperglycemia, Fatty degeneration	Altered Intercellular Communication	At multivariate analysis, PCSK9 was associated with steatosis grade (p = 0.012), older age and lower BMI, independently of sex, hyperglycemia, and fibrosis/inflammation.	27222915
Proctitis, Ulcerative Colitis	Altered Intercellular Communication	Evaluation of biomarkers for ulcerative colitis comparing two sampling methods: fecal markers reflect colorectal inflammation both macroscopically and on a cellular level.	27223407
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Simple, objective and inexpensive tools for the assessment of mucosal inflammation in ulcerative colitis (UC) are highly desirable.	27223407
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The levels of inflammation markers in feces and patch fluid distinctly reflected active inflammation in UC.	27223407
Proctitis, Inflammation	Altered Intercellular Communication	Fecal markers reflect colorectal inflammation both macroscopically and on a cellular level, and may be useful for the evaluation of subclinical inflammation.	27223407
ACSM3 gene, Inflammation, Subarachnoid Hemorrhage, Ruptured cerebral aneurysm	Altered Intercellular Communication	Toll-like receptor (TLR) signalling begins early in subarachnoid haemorrhage (SAH), and plays a key role in inflammation following cerebral aneurysm rupture.	27223696
Inflammation	Altered Intercellular Communication	The pathogenesis of PCME remains unclear, but most authors agree that inflammation plays a major role in its development.	27224076
Inflammation, Secondary immune deficiency disorder	Altered Intercellular Communication	Laboratory tests showed no signs of inflammation but showed persistent low protein- and IgG- levels, indicating a secondary immunodeficiency.	27224999
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	These findings suggested the presence of a correlation between chronic inflammation and lower urinary tract symptoms (LUTS).	27225056
Inflammation	Altered Intercellular Communication	There was also evidence of increased inflammation (C-reactive protein) in current smokers, suggesting a potential mechanism for these relationships.	27225196
Hyperammonemia, Inflammation, Dysbiosis	Altered Intercellular Communication	The mechanisms behind HE are unclear although hyperammonemia and systemic inflammation through gut dysbiosis have been proposed.	27225869
helium, Inflammation, Dysbiosis, Hyperammonemia	Altered Intercellular Communication	We found that HE patients had a significantly worse cognitive performance, systemic inflammation, dysbiosis and hyperammonemia compared to controls and cirrhotics without HE.	27225869
Inflammation, Metabolic Syndrome X, MS gene	Altered Intercellular Communication	The study was aimed to compare the release of incretins and some of early markers of inflammation at the fasting and postprandial period induced by functional oral glucose as well as lipid load in healthy controls and patients with metabolic syndrome (MS) to see if functional tests may be helpful in searching for the inflammatory status of patients.	27226181
Inflammation, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	The fat containing meals stimulate the long-lasting release of incretins, mainly GIP, parallel to the increase of the markers of low grade inflammation associating obesity in metabolic syndrome.	27226181
Inflammation, Psoriasis, Drug-Induced Ototoxicity	Altered Intercellular Communication	In severe psoriasis, liver impacting comorbidities and/or specific psoriatic inflammation, the latter mostly in PP cases, more than drug-related liver toxicity, appears to predominantly account for LTA.	27226222
Communicable Diseases, Inflammation	Altered Intercellular Communication	After 4 weeks of treatment, the inflammation and infection resolved, and the patient returned to best-corrected preinjection visual acuity.	27227391
Inflammation, White Spot Lesion	Altered Intercellular Communication	However, the white lesions reappeared, and the inflammation in the anterior chambers worsened.	27227394
Inflammation, Pseudotumor	Altered Intercellular Communication	Flow cytometry analysis showed that the peri-implant pseudotumor tissue expressed two principal phenotypes, namely macrophage-dominated and T-lymphocyte-dominated response; the average portions being 54% (macrophages) and 25% (T-lymphocytes) in macrophage-dominated inflammation and 20% (macrophages) and 54% (T-lymphocytes) in T-lymphocyte-dominated response.	27227536
Inflammation	Altered Intercellular Communication	Modification of fat metabolism may alter inflammation and disease severity.	27227540
Pain Distress Question, Inflammation	Altered Intercellular Communication	Palmitoylethanolamide (PEA), a fatty acid amide that is produced in many cells in the body, is thought to potentiate the action of endocannabinoids and to reduce pain and inflammation.	27227691
Triglycerides, Inflammation, Hypertension, CTCAE, Obesity	Altered Intercellular Communication	Cardiometabolic abnormalities were defined as 3 or more cardiometabolic risk factors (hypertension, impaired glycemic control, systemic inflammation, low high-density lipoprotein cholesterol, high triglycerides, and central obesity).	27227974
Inflammation, Prostate Cancer Outcomes Study, Endocrine System Diseases, Polycystic Ovary Syndrome	Altered Intercellular Communication	Polycystic ovarian syndrome (PCOS), the most common endocrine disorder of reproductive-aged women, is associated with systemic low-grade inflammation.	27228368
Papillary thyroid carcinoma	Altered Intercellular Communication	Papillary thyroid cancer is a disease that has been associated with chronic inflammation.	27229482
Inflammation	Altered Intercellular Communication	Histopathologically, perineural inflammation was not an uncommon feature of LS and thus may serve as a clue in the differentiation of LS from its mimickers.	27229659
Inflammation	Altered Intercellular Communication	Choroidal thickness was greater in ERM eyes with than without VMT possibly due to direct anteroposterior traction on the retina and choroid, increased vascular endothelial growth factor associated with stress on retinal pigment epithelial cells and inflammation.	27229756
Fibrosis Assessment, Necrosis with inflammation	Altered Intercellular Communication	In HBeAg-positive patients, AUCs of serum HBcrAg for predicting severe necro-inflammation and advanced fibrosis were greater than 0.70; using serum HBcrAg<=4.81x10(4)kUmL(-1) and <=2.45x10(4)kUmL(-1) as cutoffs, the sensitivities, specificities, accuracies for predicting severe necro-inflammation and advanced fbrosis were 0.697, 0.716, 0.711 and 0.818, 0.778, 0.785, respectively.	27230224
Fibrosis Assessment, Necrosis with inflammation	Altered Intercellular Communication	These results indicated favorable performances of serum HBcrAg for predicting severe necro-inflammation and advanced fibrosis in HBeAg-positive patients and significant necro-inflammation and significant fibrosis in negative patients.	27230224
Hepatitis C, Hepatitis	Altered Intercellular Communication	Hepatitis C virus (HCV) is one of the major causes of liver inflammation.	27230511
Refractory anemias	Altered Intercellular Communication	Tenascin-C, which is expressed during inflammatory conditions including RA, was seen in the articular cartilage of the incudomalleolar joints and the head of the stapes.	27230945
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation could be a causal factor in the progression of chronic kidney disease.	27234728
Inflammation, Acute epididymo-orchitis	Altered Intercellular Communication	The aim of this study was to assess the effect of systemic inflammation associated with acute epididymo-orchitis on testis steroidogenesis.	27234858
Inflammation, Bacterial Infections	Altered Intercellular Communication	There is a strong influence of ongoing systemic inflammation caused by bacterial infection on steroidogenesis in testis in acute epididymo-orchitis patients.	27234858
Colorectal Carcinoma, Gastrointestinal inflammation	Altered Intercellular Communication	IL-17 and IL-22 are linked to the development of intestinal inflammation and colorectal cancer (CRC).	27235120
Inflammation	Altered Intercellular Communication	Our results conclude that the complement system is activated in CNS during HSE in the acute phase, and interestingly also in later stages supporting previous reports of prolonged inflammation.	27235358
Inflammation	Altered Intercellular Communication	Local and chronic inflammation may be the driver of low-grade systemic inflammation.	27235406
Autoimmune Chronic Hepatitis, Insemination, Artificial, Homologous	Altered Intercellular Communication	Autoimmune hepatitis (AIH) is a chronic inflammatory condition of the liver in which the immunological mechanisms involved in tissue destruction and/or repair are still unclear.	27236154
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The fibers are similar in size and morphology to some amphibolic asbestos fibers, whose inhalation can cause chronic inflammation and cancer.	27236568
Inflammation, Viral keratitis	Altered Intercellular Communication	Among clinically defined viral keratitis cases, a negative viral swab was predominantly (93 %) observed in cases with subepithelial inflammation and was significantly associated with an increased duration of symptoms (p = 0.003).	27236644
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	Five patients were found to have associated intestinal metaplasia, and all but two had chronic inflammation.	27237135
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	Inflammation is highlighted in the pathogenesis and destabilization of atherosclerotic lesions.	27237221
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	Noninvasive identification of inflammation of atherosclerotic lesions has been challenging.	27237221
Inflammation, atherosclerotic	Altered Intercellular Communication	Therefore, we investigated the relationship between levels of circulating inflammatory markers and the degree of inflammation of atherosclerotic plaques shown by 18F-FDG uptake.	27237221
Inflammation, MS gene	Altered Intercellular Communication	In multiple sclerosis (MS) lesions blood-brain-barrier (BBB) breakdown is a common phenomenon delineating the phase of focal inflammation in developing MS lesions.	27237759
Inflammation	Altered Intercellular Communication	Although their association seems to be fortuitous, both can induce an important inflammation state that could lead to AA amyloidosis and require a close monitoring of clinical signs and acute-phase reactants.	27238193
Autoimmune Diseases, Inflammation, Systemic Vasculitis	Altered Intercellular Communication	On the other hand, microscopic polyangiitis (MPA) is a systemic autoimmune disease characterized by the inflammation of small vessels (arterioles, capillaries, and venules) mainly affecting the lung and kidney.	27238624
Inflammation, Diffuse alveolar hemorrhage, Scleroderma , Myositis, CTCAE 5.0, Pneumonia, Interstitial	Altered Intercellular Communication	The patient developed interstitial pneumonia with alveolar hemorrhage accompanied by myositis, scleroderma, and elevated anti-U1-RNP antibody and MPO-ANCA levels with substantial systemic inflammation.	27238624
Inflammation, Lung Diseases, Interstitial, Complication Aspects, Myositis, CTCAE 5.0	Altered Intercellular Communication	Strong immunosuppressive therapy (corticosteroid, intravenous immunoglobulin, and cyclosporine A) ameliorated the myositis, interstitial lung disease, and inflammation, with the decrease of MPO-ANCA levels, despite that severe lung complications are often associated with poor outcomes.	27238624
Acute suppurative inflammation	Altered Intercellular Communication	Fine-needle aspiration cytology smears showed acute suppurative inflammation with presence of fluffy basophilic colonies on Hematoxylin and Eosin staining and branched, Gram positive filamentous bacilli on Gram staining.	27238823
Arthralgia, Inflammation, Fever, CTCAE	Altered Intercellular Communication	Four patients displayed an association of fever and arthralgia, and all nine patients consistently showed laboratory markers of inflammation.	27238847
Inflammation, Fracture, Osteopenia, Diabetes Mellitus	Altered Intercellular Communication	The underlying mechanisms for increased osteopenia and fracture rates in patients with diabetes are not well understood, but may relate to chronic systemic inflammation.	27238921
Inflammation, Periodontal Diseases, Diabetes Mellitus	Altered Intercellular Communication	We assessed the effect of treating periodontal disease (POD), a cause of chronic inflammation, on inflammatory and bone turnover markers in patients with diabetes.	27238921
Anorexia Nervosa	Altered Intercellular Communication	Chronic undernourishment in the course of anorexia nervosa leads to various metabolic and hormonal changes, which translates to the impaired functioning of the majority of systems and internal organs.	27240513
ARCN1 gene, Inflammation	Altered Intercellular Communication	Despite our hypothesis suggesting that the prevalence of RLS/WED in COPD is related with systemic inflammation, we did not find a significant association between hs-CRP and COPD cases with RLS/WED.	27240804
Inflammation	Altered Intercellular Communication	Different measures of body fat composition may vary in their relations to parameters of chronic inflammation.	27241125
Inflammation	Altered Intercellular Communication	VAT, SAT, BMI, and WC show distinct associations with parameters of chronic inflammation.	27241125
Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by a chronic relapsing-remitting joint inflammation.	27241313
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Dietary interventions aimed at decreasing inflammation may be considered to improve survival of men with PCa.	27242333
Inflammation, Lupus Nephritis	Altered Intercellular Communication	Urinary soluble CD163 level reflects glomerular inflammation in human lupus nephritis.	27242373
Inflammation, Tissue injury, Kidney Diseases	Altered Intercellular Communication	In addition to classically activated macrophages that have effector roles in tissue injury, alternatively activated M2 macrophages are involved in the resolution of inflammation in animal models of kidney disease.	27242373
Inflammation	Altered Intercellular Communication	These findings indicate that the u-sCD163 level can serve as a biomarker for macrophage-dependent glomerular inflammation in human LN.	27242373
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	These findings provide new insights into the TLR4-amplified EMT process and the association between TLR4 levels and storage LUTS, suggesting chronic inflammation as vital to the pathogenesis of BPH.	27243216
Inflammation	Altered Intercellular Communication	Triggering receptor expressed on myeloid cells 1 (TREM-1) is a potent amplifier of inflammation.	27243593
Communicable Diseases, Inflammation	Altered Intercellular Communication	Medical imaging techniques are required to make a differential diagnosis and biological markers for inflammation and infection should be evaluated.	27243805
Seizures, vascular inflammations	Altered Intercellular Communication	A young female subject with ineffective pharmacological regulation of chronic vasoconstrictive-induced epilectic-like seizures was effectively treated with a dietary regimen targeted to promote vasodilatation and attenuate vascular inflammation.	27245208
Inflammation	Altered Intercellular Communication	Chemokines induce leukocyte chemotaxis and contribute to chronic inflammation.	27245471
Airway structure	Altered Intercellular Communication	Recent animal studies indicated that metformin can reduce airway inflammation.	27245632
Fibrosis Assessment, Interstitial inflammation, Kidney Diseases	Altered Intercellular Communication	Distribution and components of interstitial inflammation and fibrosis in IgG4-related kidney disease: analysis of autopsy specimens.	27246178
Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	Using 5 autopsy specimens, the present study histologically characterized the distribution and components of interstitial inflammation and fibrosis in IgG4-RKD.	27246178
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In conclusion, perivascular inflammation or fibrosis of medium- and small-sized vessels is a newly identified pathologic feature of IgG4-RKD.	27246178
Inflammation, Stanford Cancer Institute	Altered Intercellular Communication	However, urothelial inflammation and apoptosis after SCI were not significantly improved after three repeated BoNT-A injections.	27249005
Trachoma , Inflammation	Altered Intercellular Communication	These data indicate that the innate immune system is active in the immunopathology of trachoma, even in the absence of clinical inflammation.	27249027
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	CTGF might provide a direct link between inflammation and fibrosis and could be a suitable target for therapeutic treatment to halt the progression of trachomatous scarring.	27249027
Human papilloma virus infection, Uterine Cervicitis	Altered Intercellular Communication	CONCLUSIONS Older age (41-66 years), presence of HPV infection, postmenopause, cervical inflammation, and smoking are strong risk factors for cervical lesions among women in rural areas of Henan province, China.	27249229
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	SIRT6 is an important member of sirtuin family that represses inflammation, aging and DNA damage, three of which are causing factors for endothelial dysfunction.	27249230
Inflammation, Primary malignant neoplasm, Neoplasm Metastasis	Altered Intercellular Communication	Chronic inflammation is known to facilitate cancer progression and metastasis.	27249999
Inflammation, Neoplasms	Altered Intercellular Communication	Less is known about the effect of acute inflammation within the tumor microenvironment, resulting from standard invasive procedures.	27249999
Inflammation, Neoplasm Metastasis, Breast Carcinoma, Neoplasms	Altered Intercellular Communication	Therefore, biopsy-induced inflammation could have an impact on residual tumor cell progression and/or metastasis in human breast cancer.	27249999
Chronic thromboembolic pulmonary hypertension	Altered Intercellular Communication	Chronic Thromboembolic Pulmonary Hypertension Associated with Chronic Inflammation.	27250055
Inflammation	Altered Intercellular Communication	This case suggests that a relationship exists between chronic inflammation and CTEPH, and furthermore, may contribute towards elucidating the pathophysiology of CTEPH.	27250055
Inflammation, Infiltration, Psoriasis, Inflammatory dermatosis, Peeling of skin	Altered Intercellular Communication	Psoriasis is a chronic inflammatory skin disease characterized by plaques with inflammation, infiltration, hyper-/parakeratosis and desquamation.	27250651
Calcification of coronary artery, Chronic Kidney Diseases	Altered Intercellular Communication	Systemic Inflammation Is Associated With Coronary Artery Calcification and All-Cause Mortality in Chronic Kidney Disease.	27251163
Inflammation, Calcification of coronary artery, Chronic Kidney Diseases, SLC25A20 gene	Altered Intercellular Communication	Presence of systemic inflammation in chronic kidney disease (CKD) is associated with advanced coronary artery calcification (CAC).	27251163
Inflammation, SLC25A20 gene	Altered Intercellular Communication	We evaluated the associations between CAC, estimated glomerular filtration rate (eGFR) and all-cause mortality, to determine whether the associations differ according to the presence of systemic inflammation.	27251163
Inflammation, Cardiotoxicity, Takotsubo Cardiomyopathy, Colorectal Carcinoma, Coronary Artery Vasospasm	Altered Intercellular Communication	Despite the high therapeutic efficacy of 5-FU in treatment of colorectal cancer, it is associated with undesired cardiac toxicities including coronary spasms, toxic inflammation and takotsubo cardiomyopathy.	27251602
Granulomatous inflammation	Altered Intercellular Communication	Several punch biopsies exhibited non-specific granulomatous inflammation without demonstrable fungi or mycobacteria in histochemical stains.	27251900
Inflammation	Altered Intercellular Communication	It usually occurs in the setting of chronic inflammation.	27252231
Depression, CTCAE, Erectile dysfunction	Altered Intercellular Communication	Similarly, change in erectile dysfunction over time was associated with mortality over 7 years in univariate (odds ratio: 1.69, 95% CI: 1.34-2.14) and multivariate analysis, including hormones, but not after adjusting for depression (odds ratio: 1.24, 95% CI: 0.95-1.62).	27252309
Inflammation, Malignant Neoplasms, Cyst	Altered Intercellular Communication	The final diagnoses were malignant or premalignant tumors in 10 patients (29.4%), stones in nine patients (26.5%), inflammation in 14 patients (41.2%), and cyst in one patient (2.9%).	27254755
Inflammation, Neoplasms	Altered Intercellular Communication	The diagnostic accuracies of stones, inflammation, and AOV tumors were 100.0%, 94.1%, and 91.1%, respectively.	27254755
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Clinically, most patients presented with fever and local inflammation.	27255172
Inflammation, Structure of beta Cell of islet, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Pancreatic b-cell dysfunction resulting from inflammation has been recognized to contribute to type 2 diabetes mellitus (T2DM).	27255377
Inflammation, Carcinogenesis, Neoplasms	Altered Intercellular Communication	Emerging evidences indicate that inflammation plays a crucial role in carcinogenesis and tumor progression.	27255479
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	iMAP depicted fibrosis in the vessel (green areas) and nonfibrotic tissue change suggestive of inflammation outside the vessel (yellow/red areas).	27255645
Arthralgia, Inflammation, Fever, CTCAE	Altered Intercellular Communication	A 4.5-year-old Caucasian boy presented with fever of 4 days' duration followed by debilitating migratory arthralgia and inflammation.	27255933
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Histological samples of affected organs taken from seven patients showed granulomatous inflammation in six, with caseating necrosis in five.	27256154
Inflammation	Altered Intercellular Communication	The stroma exhibited extensive desmoplasia and chronic inflammation.	27256178
Communicable Diseases, Inflammation	Altered Intercellular Communication	An attempt was made to find a diagnostic test capable of identifying the infectious process underway, but clinical scales and biomarkers of inflammation helped us to achieve acceptable results.	27256282
Alzheimers Disease", Inflammation	Altered Intercellular Communication	Genetic risk factors for Alzheimer's disease imply that inflammation plays a causal role in development of the disease.	27256292
Inflammation, Sleep Apnea, Obstructive, Blood Vessel, Osage language	Altered Intercellular Communication	Oxidative stress and inflammation are assumed as the main pathological triggers for vascular damage in hypersomnolent obstructive sleep apnoea (OSA) patients, whereas their exact role in less symptomatic population is currently unknown.	27256793
Inflammation, Blood Vessel, Osage language	Altered Intercellular Communication	To determine whether oxidative stress (urinary 8-isoprostane concentration) and inflammation (plasma resistin levels) are associated with vascular damage in non-hypersomnolent (Epworth Sleep Score <11) OSA patients.	27256793
Myocarditis	Altered Intercellular Communication	Endocardial inflammation is more common in left atrial appendage irrespective of rhythm.	27256970
Inflammation, Ischemic stroke, Brain Infarction	Altered Intercellular Communication	Although plasma C-reactive protein (CRP) is elevated in response to inflammation caused by brain infarction, the association of CRP with clinical outcomes after acute ischemic stroke remains uncertain.	27258004
Airway structure, Asthma, Bronchoconstriction	Altered Intercellular Communication	In asthma, FENO50 increases with bronchodilation and decreases with bronchoconstriction, the latter potentially causing an underestimate of the degree of airway inflammation when asthma worsens.	27258087
methyldopa, Inflammation	Altered Intercellular Communication	Age-related macular degeneration (AMD) is a multifactorial disease, in which complement-mediated inflammation plays a pivotal role.	27258093
Polyuria, Polydipsia, Nephrogenic Diabetes Insipidus, Nephrogenic Diabetes Insipidus, Type I	Altered Intercellular Communication	Nephrogenic diabetes insipidus (NDI) is a condition resulting from the kidney's impaired response to circulating antidiuretic hormone (ADH), leading to polydipsia and polyuria.	27258490
Dermatitis	Altered Intercellular Communication	He was found to have significant skin inflammation, predominantly involving areas of tattoos.	27258541
Inflammation	Altered Intercellular Communication	Skin biopsy demonstrated granulomatous inflammation of the dermis with tattoo pigment evident in numerous histiocytes.	27258541
Inflammation, Uveitis	Altered Intercellular Communication	The authors report another rare case of tattoo-associated uveitis, in which inflammation is limited to tattooed skin and the uvea.	27258541
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Aerobic, resistance and combined training and detraining on body composition, muscle strength, lipid profile and inflammation in coronary artery disease patients.	27258806
Inflammation	Altered Intercellular Communication	lipid and apolipoprotein profile and inflammation status) parameters, while the return to baseline values during the detraining period was slower compared to the other exercise modalities.	27258806
Allergic sensitization	Altered Intercellular Communication	The results are of interest as they demonstrate that genetic variations in inflammation-related genes within the MHC can influence chemical-induced skin irritation and may explain the connection between inflamed skin and propensity to subsequent allergic contact sensitization.	27258892
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Conditioned medium derived from rat amniotic epithelial cells confers protection against inflammation, cancer, and senescence.	27259996
IL13 gene, Rhinitis	Altered Intercellular Communication	Allergic rhinitis (AR) occurs when the symptoms of rhinitis arise as a result of allergen-induced nasal mucosal inflammation.	27260602
Pleural Tuberculosis	Altered Intercellular Communication	It can result from diverse inflammatory conditions, especially tuberculous pleurisy.	27261452
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Executive functioning and diabetes: The role of anxious arousal and inflammation.	27261922
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Chronically high anxious arousal and inflammation increase one's risk of developing type 2 diabetes.	27261922
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	We sought to evaluate anxious arousal and inflammation as underlying mechanisms linking inhibition with diabetes incidence.	27261922
Inflammation, Carcinogenesis, ovarian neoplasm	Altered Intercellular Communication	While inflammation has been shown to play an important etiologic role in ovarian carcinogenesis, little is known about the association between inflammatory properties of diet and ovarian cancer risk.	27262447
Inflammation, Panuveitis, Uveitis	Altered Intercellular Communication	Volunteers with histories of unilateral or bilateral anterior segment inflammation (anterior, intermediate, or panuveitis); included were 52 patients (84 eyes with uveitis).	27262766
Cerebrovascular accident	Altered Intercellular Communication	Correlation of the L-Arginine Pathway with Thrombo-Inflammation May Contribute to the Outcome of Acute Ischemic Stroke.	27263035
Ischemic stroke	Altered Intercellular Communication	Concentration of L-arginine and ADMA/SDMA differentially correlates with thrombo-inflammation in the hyperacute phase of ischemic stroke.	27263035
Inflammation, Disorder of tendon	Altered Intercellular Communication	We sought evidence of interleukin 17A (IL-17A) expression in early human tendinopathy and thereafter, explored mechanisms whereby IL-17A mediated inflammation and tissue remodeling in human tenocytes.	27263531
Communicable Diseases, Inflammation	Altered Intercellular Communication	Oncology (67%) and neurology/psychiatry (66%) were the most frequent target indications pursued by companies followed by inflammation (48%), cardiovascular (43%), metabolic (39%), infectious (37%), orphan (32%) and respiratory (29%) diseases.	27263834
Communicable Diseases, Inflammation, Fever, CTCAE	Altered Intercellular Communication	Fever in the intensive care unit (ICU) is usually an adaptive response to infection or inflammation.	27264198
ARCN1 gene, Inflammation, Asthma, Occupational	Altered Intercellular Communication	The aim of this study was to compare the sputum and serum markers of inflammation in patients with occupational asthma and COPD.	27265531
Renal Insufficiency, Inflammation, Chronic Kidney Diseases, Uremia	Altered Intercellular Communication	Chronic renal failure patients suffer from chronic inflammation that results from factors such as impaired renal function, accumulation of uremic toxins and bio incompatibility of dialyzer membranes.	27267129
Inflammation, Retinitis Pigmentosa, polychondritis, Collagen Diseases	Altered Intercellular Communication	Relapsing polychondritis (RP) is a rare rheumatologic disorder in which recurrent episodes of inflammation result in destruction of cartilage of the ears and nose.	27267190
Uremia, Inflammation	Altered Intercellular Communication	The response of erythropoietic stimulating agents (ESA) in uremic patients may be associated with the changes of biochemical parameters, metal elements and inflammation status during the shift from one ESA to another.	27267426
Inflammation	Altered Intercellular Communication	IRs had a significantly lower initial T-CHOL (p=0.03) and initial CRP (p=0.012) than non-responders, which may be related to lower inflammation.	27267426
Inflammatory abnormality of the eye	Altered Intercellular Communication	It seems to be safe to use 100% autologous serum despite earlier suspicions regarding immune complex accumulations and exacerbation of ocular surface inflammation.	27267447
Inflammation, Demyelination, Edema, Encephalomyelitis, Acute Disseminated	Altered Intercellular Communication	The underlying pathogenesis of ADEM may include perivascular inflammation, oedema and demyelination in the central nervous system.	27268491
Gingivitis, Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Elevated levels of GCF RANTES in MetS patients with gingivitis might associate with the presence of increased gingival inflammation by MetS.	27270225
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Low-grade systemic inflammation associated with MetS and adipose tissue-derived RANTES might lead to altered GCF RANTES levels in the presence of gingival inflammation.	27270225
Heart Diseases, Inflammation	Altered Intercellular Communication	Adipose-derived adipokines have been demonstrated to be associated with the development of experimental heart disease through chronic inflammation and cardiac cell apoptosis.	27270246
Inflammation, Hostility	Altered Intercellular Communication	Hostility has been associated with higher basal levels of inflammation.	27270459
Inflammation	Altered Intercellular Communication	Such models would improve the ranking of candidates for liver transplantation by differentiating the severe patients with persistent systemic inflammation and intermediate MELD scores.	27271159
Degenerative polyarthritis	Altered Intercellular Communication	Our data support an anti-senescence and anti-inflammatory role for the C-terminal moiety of PTHrP with potential applications in chronic inflammatory conditions such as OA.	27271252
Inflammation, Myocardial, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Radiofrequency catheter ablation versus balloon cryoablation of atrial fibrillation: markers of myocardial damage, inflammation, and thrombogenesis.	27271554
Inflammation, Chronic sinusitis	Altered Intercellular Communication	Natural killer cells regulate eosinophilic inflammation in chronic rhinosinusitis.	27271931
Inflammation, Impaired T cell function	Altered Intercellular Communication	This decrease was associated with NK cell dysfunction and eosinophilic inflammation.	27271931
eosinophil, Inflammation, Craniosynostosis	Altered Intercellular Communication	In a murine model of CRS, NK cell depletion caused an exacerbation of blood eosinophilia and eosinophilic inflammation in the sinonasal tissue.	27271931
Inflammation, Craniosynostosis	Altered Intercellular Communication	Thus, our results suggest decreased NK cell-mediated eosinophil regulation, possibly through an increased level of PGD2, as a previously unrecognized link between PG dysregulation and eosinophilic inflammation in CRS.	27271931
Myocarditis	Altered Intercellular Communication	Pericardial inflammation with reversible constriction: prediction of recovery with cardiovascular magnetic resonance.	27271935
Acne, Hyperandrogenism	Altered Intercellular Communication	As androgenic hormones play a very important role in the acne pathogenesis, the early diagnosis of hyperandrogenic states is very useful for the proper evaluation of each patient and for a better choice of therapeutic management.	27272708
Inflammation, Pain Distress Question	Altered Intercellular Communication	A new finding in the present work is a significant correlation in the NRS scale versus plasma concentrations of anti-inflammatory cytokine IL-10 and pro-inflammatory cytokine IL-1b postoperatively suggesting that inflammation and pain are related.	27272818
Inflammation, Neoplasms	Altered Intercellular Communication	In addition to their unfavorable role as mediators of evasion from antitumor immune response, Tregs might also have a beneficial role by reducing inflammation thereby limiting early tumor growth and spreading.	27272839
Inflammation, Peripheral Arterial Diseases	Altered Intercellular Communication	Association between gait characteristics and endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease.	27273077
Inflammation	Altered Intercellular Communication	Abnormalities of mineral metabolism and inflammation may affect the cardiovascular system.	27273357
Left Ventricular Hypertrophy, Inflammation, Ventricular hypertrophy	Altered Intercellular Communication	We have assessed the relationship of left ventricular hypertrophy (LVH) with inflammation and mineral metabolism.	27273357
Inflammation, Asthma	Altered Intercellular Communication	AEs of cold, upper respiratory inflammation and asthmatic attack occurred in each of the 3 patients (8.6%); however, these were not regarded as treatment-related AEs.	27273710
Inflammation	Altered Intercellular Communication	The mechanism of action is unknown, but it may be mediated by inflammation.	27274008
Refractory anemias, Inflammation	Altered Intercellular Communication	Genetic markers of RA susceptibility located within HLA-DRB1 determine the levels of clinical and systemic inflammation independently, and also determine all objective measures of disease activity and outcome.	27274008
ARCN1 gene, Inflammation	Altered Intercellular Communication	Extracellular cadmium in the bronchoalveolar space of long-term tobacco smokers with and without COPD and its association with inflammation.	27274222
Steatohepatitis, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	The degrees of liver steatosis, lobular inflammation and fibrosis were determined based on the non-alcoholic fatty liver activity score (NAS) by a single expert pathologist.	27275102
Steatohepatitis, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Receiver operating characteristic (ROC) analysis was employed to determine cut-off values of serum adipokines to discriminate the grades of liver steatosis, lobular inflammation and fibrosis.	27275102
Inflammation	Altered Intercellular Communication	Elevated serum IL-6 and IL-8 levels were associated independently with advanced lobular inflammation [b = 1.4 (95%CI: 1.09-1.8), 1.07 (95%CI: 1.003-1.15), P < 0.05].	27275102
Inflammation	Altered Intercellular Communication	Xanthogranulomatous inflammation in the spinal epidural space is extremely rare.	27276211
Inflammation, Lymphoma	Altered Intercellular Communication	We report a case of a 62-year-old man with a xanthogranulomatous inflammation in the spinal epidural space mistaken for lymphoma because of its avid F FDG uptake on PET/CT.	27276211
Xanthogranulomatous inflammation	Altered Intercellular Communication	This case emphasizes the need for caution when evaluating a spinal epidural mass using F FDG PET/CT as xanthogranulomatous inflammation can induce a false-positive reading on F-FDG PET/CT.	27276211
Inflammation, Unspecified visual loss	Altered Intercellular Communication	A 75-year-old Asian male with bilateral phacoemulsification and intraocular lens implantation developed severe inflammation with sharp vision loss in both eyes after the surgeries.	27277218
Inflammation	Altered Intercellular Communication	After 5 days of medication, the inflammation was markedly relieved, and no recurrence was observed 2 weeks later.	27277218
Inflammation	Altered Intercellular Communication	These effects were attenuated following treatment with exogenous IGF1, thus indicating that the miR-206/IGF1 signaling pathway may be considered a novel therapeutic target for the treatment of AD-associated microglial inflammation.	27277332
Inflammation	Altered Intercellular Communication	Many chemical agents are tried to induce inflammation and damage of the pleural mesothelial layer to achieve this symphysis.	27277376
Inflammation, Immunocompromised Host, Necrotizing herpetic retinopathy	Altered Intercellular Communication	Necrotizing herpetic retinopathy in an immune-compromised pediatric patient with minimal signs of inflammation: case report.	27277425
Inflammation, Bronchopleural Fistula	Altered Intercellular Communication	Postoperative pyothorax (PP) following development of a bronchopleural fistula (BPF) after lung surgery induces continuous inflammation and may affect the occurrence of AE.	27277761
Cessation of life, Inflammation	Altered Intercellular Communication	Our second goal was to determine whether traumatic deaths with different survival times, septic deaths, and deaths in individuals suffering from diseases with significant systemic inflammation are systematically characterized by increased concentrations of total IgE in postmortem serum from femoral blood.	27277898
Inflammation, Fibrosis Assessment, Edema, Acute hepatitis, Cholestasis	Altered Intercellular Communication	Acoustic radiation force impulse (ARFI) imaging techniques were recently developed to measure liver fibrosis, but their specificity is impaired by cholestasis, inflammation, or edema in acute hepatitis.	27277904
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Pentraxin 3 (PTX3) is an inflammatory molecule that is involved in immune responses, inflammation, and cancer.	27278519
Myositis, Edema, Fatty infiltration	Altered Intercellular Communication	It may identify muscle inflammation (edema) and fatty infiltration for evaluation of disease activity and damage.	27279002
Vasculitis, Prediabetes syndrome	Altered Intercellular Communication	The results support the beneficial effects of RO extract on the control of glycemia and vascular inflammation in prediabetic patients.	27279471
Inflammation	Altered Intercellular Communication	The typical histopathology is that of necrotizing granulomatous inflammation with palisading histiocytes, neutrophils, and lymphocytes.	27279517
Inflammation	Altered Intercellular Communication	LLRs are associated with a vaccine-specific IgE response and IP-10, whereas SRs demonstrate increased systemic inflammation without a skewed cytokine profile.	27280620
Inflammation, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	From 1994 to 2014, 543 patients with stage 5 CKD (median age =56 years old; 63% men; 199 patients had CVD) took part in our study on malnutrition, inflammation, and CVD in incident dialysis patients.	27281698
Inflammation, Cachexia	Altered Intercellular Communication	Protein energy wasting and systemic inflammation are prevalent in maintenance hemodialysis (MHD) patients.	27281699
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Primary inclusion criteria included signs of chronic inflammation (average C-reactive protein of >=5 mg/L over three consecutive measurements), lack of active infectious or inflammatory disease, no hospitalization within 1 month prior to the study, and not receiving steroids (>5 mg/d) and/or immunosuppressive agents.	27281699
Inflammation	Altered Intercellular Communication	High-dose o-3 supplementation over 12 weeks in MHD patients with systemic inflammation was associated with attenuation of forearm muscle protein breakdown but did not influence skeletal muscle protein synthesis, skeletal muscle net protein balance or any component of the whole-body protein balance.	27281699
Diabetes Mellitus	Altered Intercellular Communication	Arterial Stiffness Is Positively Associated With 18F-fluorodeoxyglucose Positron Emission Tomography-Assessed Subclinical Vascular Inflammation in People With Early Type 2 Diabetes.	27281773
Arterial Stiffness, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The possible relationship between subclinical arterial inflammation assessed by (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) and arterial stiffness was investigated in patients with early type 2 diabetes.	27281773
Arterial Stiffness, Diabetes Mellitus, Non-Insulin-Dependent, Arteritis	Altered Intercellular Communication	In patients with type 2 diabetes, FDG-PET/CT-imaged subclinical arterial inflammation is positively associated with determinants of arterial stiffness.	27281773
Conn Adenoma	Altered Intercellular Communication	Expression of inflammation-related genes in aldosterone-producing adenomas with KCNJ5 mutation.	27282482
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Cytokine-mediated inflammation is important in the pathogenesis of non-small cell lung cancer (NSCLC).	27282611
Inflammation, Asthma	Altered Intercellular Communication	The presence of eosinophilic (type 2) inflammation in some but not all patients with severe asthma predicts responsiveness to current treatments, but new treatment approaches will require a better understanding of non-type 2 mechanisms of severe asthma.	27283230
Inflammation, Asthma	Altered Intercellular Communication	We considered the possibility that systemic inflammation, which arises in subgroups of obese and older patients, increases the severity of asthma.	27283230
Inflammation, Asthma, physiopathological	Altered Intercellular Communication	Interleukin-6 (IL-6) is a biomarker of systemic inflammation and metabolic dysfunction, and we aimed to explore the association between IL-6 concentrations, metabolic dysfunction, and asthma severity.	27283230
Inflammation, Asthma, physiopathological	Altered Intercellular Communication	Systemic IL-6 inflammation and clinical features of metabolic dysfunction, which occur most commonly in a subset of obese asthma patients but also in a small subset of non-obese patients, are associated with more severe asthma.	27283230
Inflammation	Altered Intercellular Communication	Lipid accumulation and chronic inflammation occur in the sIA wall.	27283327
PROS1 gene, Arthritis, Psoriatic, Psoriasis	Altered Intercellular Communication	Psoriatic arthritis (PsA) is a potentially severe inflammatory condition (entheso-arthro-osteopathy), and early diagnosis is important to guide treatment choices in patients with psoriasis.	27283499
Stomach Carcinoma	Altered Intercellular Communication	Systemic immune-inflammation index, thymidine phosphorylase and survival of localized gastric cancer patients after curative resection.	27283904
Inflammation, Calcinosis	Altered Intercellular Communication	Osteopontin (OPN) is a secreted glycophosphoprotein that has a role in inflammation, immune response and calcification.	27284698
Inflammation	Altered Intercellular Communication	In addition the decreased IGF-I serum levels may affect the modulation of inflammation and lesion healing in chronic phase.	27286813
Inflammation, Menopause	Altered Intercellular Communication	Exploring Black-White Differences in the Relationship Between Inflammation and Timing of Menopause.	27287275
Inflammation	Altered Intercellular Communication	Prior research on inflammatory chronic conditions suggests that inflammation may predict how early women experience menopause.	27287275
Communicable Diseases, Inflammation	Altered Intercellular Communication	The hs-CRP levels associated with HS appear to be intermediate (2.2-5.1 mg/l), implying systemic inflammation rather than infection.	27287331
Inflammation, Tuberculosis, Pulmonary	Altered Intercellular Communication	They were analysed for response to DLCP in terms of IOP control, vision-related complications, increased inflammation, post-trabeculectomy hypotony and chances of phthisis and ciliary shutdown.	27287344
Inflammation, Ocular Hypotension, Suprachoroidal hemorrhage	Altered Intercellular Communication	There were no other complications like increased inflammation, prolonged hypotony or suprachoroidal haemorrhage.	27287344
Diverticulosis, Inflammation, Diverticulitis, Malignant Neoplasms	Altered Intercellular Communication	Of the patients with CT scans suggestive of diverticulitis, follow-up colonoscopy showed 3 with diverticulosis, 2 with malignancies, and 1 with nonspecific inflammation.	27287835
Inflammation, Injury of liver	Altered Intercellular Communication	Lipocalin 2 (LCN2) is induced in the injured liver and associated with inflammation.	27288631
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Characteristics of daily social interactions among midlife and older adults associate with markers of systemic inflammation that are known to predict risk for cardiovascular disease.	27288715
Inflammation, Infection by Cryptococcus neoformans, Nocardia Infections, Tuberculosis, Zygomycosis, Mycobacterium Infections	Altered Intercellular Communication	The most common cytological diagnosis was mucormycosis (n = 13) followed by nocardiosis (n = 8) and necrotising inflammation (n = 7), tuberculosis (n = 6), cryptococcosis (n = 2), aspergillosis(n = 2), histoplasmosis(n = 1) and atypical mycobacterial infection (n = 1).	27292015
Inflammatory cardiomyopathy, Myocarditis	Altered Intercellular Communication	Endomyocardial miR-133a levels correlate with myocardial inflammation, improved left ventricular function, and clinical outcome in patients with inflammatory cardiomyopathy.	27292200
Inflammation, Heart failure	Altered Intercellular Communication	A set of six microRNAs implicated in inflammation (miR-155 and miR-146b), heart failure (miR-21 and miR-133a), and endothelial cell (miR-126) and skeletal muscle function (miR-206) was pre-defined.	27292200
Inflammation, Pneumoconiosis	Altered Intercellular Communication	The association between pneumoconiosis and coal mine dust contiguity is thought to be due to the effect of coal dust by producing chronic inflammation.	27292375
Inflammation	Altered Intercellular Communication	In this study, ocular findings suggest that systemic levels of trace elements and chronic inflammation may not reach to a level that influences ocular structures.	27292375
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1, Retinitis Pigmentosa, polychondritis, Inflammation	Altered Intercellular Communication	Relapsing polychondritis (RP) is a rare, multisystem autoimmune disease characterized by inflammation, structural damage, and impaired function of cartilaginous tissues throughout the body.	27292528
Refractory anemias, Rheumatoid Arthritis, Arthritis, Autoimmune Diseases	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a systemic autoimmune disease with chronic joint inflammation characterized by activated T cells.	27294146
Inflammation	Altered Intercellular Communication	Coenzyme Q10 (CoQ10) deficiency has been associated with statin-induced myopathy, and supplementation with CoQ10 may reduce inflammation markers.	27294339
Vascular Diseases, Inflammation	Altered Intercellular Communication	Relationships between CoQ10, subclinical vascular disease, and biomarkers of inflammation and immune activation were explored using Spearman correlations and multivariable regression models.	27294339
Inflammatory Bowel Diseases, Rheumatoid Arthritis, Lymphoproliferative Disorders, "wegeners granuloma", vascular inflammations, Lupus Erythematosus	Altered Intercellular Communication	There are reported cases of coexistence with systemic lupus erythematosus, rheumatoid arthritis, Wegener's granuloma, inflammatory bowel disease, generalized vascular inflammation, and lymphoproliferative disorders.	27294654
Vasculitis, Leukocytoclastic, Cutaneous, Granulomatous inflammation	Altered Intercellular Communication	It is probable that the deposition of immune complexes in blood vessels leads to cutaneus leukocytoclastic vasculitis, degeneration of collagen fibres and palisaded granulomatous inflammation.	27294654
Inflammation, Breast Carcinoma	Altered Intercellular Communication	Inflammation may play a role in breast cancer, but evidence in the general population is lacking.	27294662
Inflammation, Primary malignant neoplasm, Obesity	Altered Intercellular Communication	Our findings support a role of inflammation in BCa mortality which may involve mechanisms apart from obesity, and potential usefulness of GLR as a marker in assessing inflammation and cancer.	27294662
Inflammation, Malabsorption Syndrome, physiopathological, Growth Disorders	Altered Intercellular Communication	Environmental enteric dysfunction, an asymptomatic condition characterized by inflammation of the small bowel mucosa, villous atrophy, malabsorption, and increased intestinal permeability, is a major contributor to childhood stunting in low-income countries.	27294788
Inflammation, Carotid Atherosclerosis	Altered Intercellular Communication	Galectin-3 binding protein (Gal-3BP) is a secreted protein associated with inflammation and carotid atherosclerosis.	27295060
Inflammation, Thrombosis, diabetic	Altered Intercellular Communication	The cold effects on circulatory inflammation, thrombosis and vasoconstriction in type 2 diabetic patients.	27295598
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	We aimed to examine the associations between ambient temperature and circulating biomarkers of inflammation, coagulation and vasoconstriction.	27295598
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Sixteen biomarkers of inflammation, coagulation and vasoconstriction were repeatedly measured over six follow-ups.	27295598
Inflammation	Altered Intercellular Communication	Chronic systemic inflammation contributes to the development of adverse health conditions, yet the influence of fixed and modifiable risk factors on many serologic biomarkers of inflammation remains largely unknown.	27295613
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Oxidative stress and inflammation are associated with physical frailty in patients with Alzheimer's disease.	27296166
Inflammation, Data types - Address	Altered Intercellular Communication	The present results strongly suggest that oxidative stress and inflammation are involved in the pathophysiology of frailty status in individuals with AD.	27296166
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	All lesions were histologically or clinically confirmed (malignancy: inflammation = 24:20).	27298058
Liver carcinoma	Altered Intercellular Communication	Preoperative inflammation-based markers predict early and late recurrence of hepatocellular carcinoma after curative hepatectomy.	27298102
FAM126A gene	Altered Intercellular Communication	Preoperative inflammation-based prognostic factors predict early and late recurrence of HCC after curative resection.	27298102
Malaria, Falciparum, Prediabetes syndrome, Obesity, diabetic	Altered Intercellular Communication	Increased Oxidative Stress and Inflammation Independent of Body Adiposity in Diabetic and Nondiabetic Controls in falciparum Malaria.	27298824
Malaria, Falciparum, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Information on the extent to which oxidative stress and inflammation occur in the presence of falciparum malaria and type 2 diabetes mellitus in the same individual is limited.	27298824
Malaria, Falciparum, Inflammation	Altered Intercellular Communication	Uncomplicated falciparum malaria elevated inflammation and peroxidation but decreased antioxidant power independent of adiposity.	27298824
Inflammation, Thrombocytopenia, Extravasation, Puumala virus	Altered Intercellular Communication	Thrombocytopenia associates with the severity of inflammation and variables reflecting capillary leakage in Puumala Hantavirus infection, an analysis of 546 Finnish patients.	27299174
Acute Kidney Injury, CTCAE, Inflammation, Extravasation, Thrombocytopenia	Altered Intercellular Communication	The severity of thrombocytopenia associates with the degree of inflammation and variables reflecting capillary leakage, but not with the severity of acute kidney injury in PUUV infected Finnish patients.	27299174
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Viscous formulation increases mucosal contact time resulting in a greater decrease in mucosal inflammation.	27299595
Primary malignant neoplasm	Altered Intercellular Communication	Systemic and local inflammations have been described as relevant prognostic factors in patients with cancer.	27300446
Inflammation, Ulcerative Colitis, Hepatobiliary Disorder, Fibrosis, Liver, Carcinogenic Chlorinated Hydrocarbon, How Much Bothered by Arm Heaviness in Affected Arm	Altered Intercellular Communication	Determining the level of TNFa allows to evaluate the severity of liver disease, heaviness and progression of liver fibrosis speed in CHC, and the severity of inflammation in the intestinal mucosa in UC.	27301136
Fibrosis Assessment, Heart failure, Myocarditis	Altered Intercellular Communication	Galectin-3 is a marker of myocardial inflammation and fibrosis shown to correlate with morbidity and mortality in heart failure (HF).	27301475
Leukoencephalopathy, Inflammation, Leukoencephalopathy, Progressive Multifocal	Altered Intercellular Communication	We diagnosed progressive multifocal leukoencephalopathy (PML) with controlled inflammation.	27301518
Inflammation, Fibrosis Assessment, Liver Cirrhosis	Altered Intercellular Communication	Biopsy specimens with less fibrosis and/or mild portal inflammation showed significantly more staining than those with cirrhosis (P < 0.001), or at least moderate inflammatory activity (P < 0.001).	27302660
Inflammation	Altered Intercellular Communication	There was no significant association between lobular inflammation (P = 0.06), bilirubin levels or viral load and immunohistochemical staining for serum amyloid A.	27302660
Small cell carcinoma of lung, Adrenal cortical hypofunction	Altered Intercellular Communication	According to low levels of serum cortisol, elevated adrenocorticotropic hormone (ACTH) and rapid ACTH test, the diagnosis of adrenal insufficiency associated with SCLC was made.	27302729
Myelofibrosis, Inflammation, Molecular Abnormality	Altered Intercellular Communication	Along with molecular abnormalities (mutations in JAK2, Calreticulin (CALR) and MPL genes), chronic inflammation is the major hallmark of Myelofibrosis (MF).	27304059
Inflammation, Dysplasia	Altered Intercellular Communication	However, severe inflammation may induce reactive epithelial cell changes and hence mimic histologic dysplasia.	27305938
Communicable Diseases, Inflammation, Craniosynostosis	Altered Intercellular Communication	In a population of CRS patients with active infection or inflammation, we sought to determine if a correlation between T2R38 phenotype and in vitro biofilm formation existed.	27309535
Inflammation, Hyperintensity of cerebral white matter on MRI	Altered Intercellular Communication	To examine associations between inflammation and physical function and potential mediation by white matter hyperintensities (WMHs) in African Americans (AAs) and European Americans (EAs).	27310030
Inflammation, Microvascular Angina	Altered Intercellular Communication	Inflammation may contribute to physical function impairments through pathways other than brain microvascular disease, particularly in AAs.	27310030
Inflammation	Altered Intercellular Communication	This implied that leukocyte migration and inflammation cascade activation might contribute to frailty, in addition to monocyte/macrophage-mediated immuno-inflammation.	27310835
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Adjustment for left ventricular morphology, metabolic syndrome, and systemic inflammation was also performed.	27311062
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Associations were unchanged when accounting for health behaviors, markers of systemic inflammation, and the metabolic syndrome.	27311062
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	However, currently ST2 (member of the interleukin 1 receptor family) has emerged as marker of inflammation, fibrosis and cardiac stress.	27311068
Chorioretinitis, Inflammation, Toxoplasmosis	Altered Intercellular Communication	Inflammation due to retinal neuroepithelial necrotic granulomas of toxoplasmosis can extend to neighbor areas and may develop focal adhesions of the posterior hyaloid, to the surface vessels, and the margins or adjoining areas of retinochoroiditis plaques.	27312206
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Further research is needed to understand the roles that CRP and systemic inflammation play in CKD risk.	27312245
Airway structure	Altered Intercellular Communication	Eighty-seven subjects (9.6%) had incidental findings that required further investigation, 42 (4.6%) from lower airways inflammation.	27312516
Upper Respiratory Infections	Altered Intercellular Communication	Clinically important incidental findings were found in 9.4%, predominantly related to lower respiratory tract inflammation.	27312516
Inflammation, Atherosclerosis	Altered Intercellular Communication	High-density lipoprotein (HDL)-bound paraoxonase-1 (PON-1) is mechanistically related to oxidative stress, inflammation and atherosclerosis and this multirole nature positions the enzyme as potential pathogenic player and candidate biomarker for many diseases.	27312742
Inflammation, Unipolar Depression	Altered Intercellular Communication	There is mixed evidence in the literature on the role of inflammation in major depressive disorder.	27313138
Depressive disorder, Inflammation	Altered Intercellular Communication	Our well-characterized examination of cytokine plasma levels did not support the association of major depressive disorder with systemic inflammation.	27313138
Gastrointestinal inflammation	Altered Intercellular Communication	Platelet interaction with lymphatics aggravates intestinal inflammation by suppressing lymphangiogenesis.	27313177
Inflammation, Colitis	Altered Intercellular Communication	Our data suggest that despite elevated lymphangiogenic factors during colonic inflammation, platelet migration to LVs resulted in suppressed lymphangiogenesis, leading to aggravation of colitis by blocking the clearance of inflammatory cells.	27313177
Inflammation	Altered Intercellular Communication	Sensory evoked potentials suggested proximal demyelination and lumbosacral plexus imaging suggested inflammation.	27313227
TG gene, Inflammation	Altered Intercellular Communication	Plasma periostin levels were strongly associated with plasma TG, chronic inflammation, and insulin resistance.	27313402
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation in the airway and lung.	27313452
Inflammation, Stomach Carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Inflammation and hormonal signalling induce the cyclooxygenase-2 (COX-2) expression in various human cancers including Gastric Cancer (GC).	27314294
Inflammation, Stomach Carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Inflammation and hormonal signalling induce the cyclooxygenase-2 (COX-2) expression in various human cancers including Gastric Cancer (GC).	27314294
Inflammation, Stomach Carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Inflammation and hormonal signalling induce the cyclooxygenase-2 (COX-2) expression in various human cancers including Gastric Cancer (GC).	27314294
Alzheimers Disease", Data types - Address, Penile Diseases	Altered Intercellular Communication	Moreover, current knowledge on brain monoaminergic neurotransmitter deficiencies in this presenile disorder is scarce, particularly with reference to changes in Alzheimer's disease (AD).	27314528
Inflammation, Microbial Biofilms, Presenile dementia, Chronic infectious disease, Data types - Address	Altered Intercellular Communication	Spirochetes evade host defenses, locate intracellularly, form more resistant atypical forms and notably biofilms, which contribute to sustain chronic infection and inflammation and explain the slowly progressive course of dementia in AD.	27314530
Psoriatic Juvenile Idiopathic Arthritis, Inflammation, Psoriasis	Altered Intercellular Communication	Treatment with phototherapy in patients with psoriasis may affect systemic inflammation by downregulation of the expression of genes encoding proinflammatory cytokines in PBMCs, implicated in the development of psoriasis and psoriatic comorbidities.	27314537
Atherosclerosis	Altered Intercellular Communication	Atherosclerosis is a pro-inflammatory condition, in which leucocyte activation plays an important role.	27314629
Inflammation	Altered Intercellular Communication	Based on these results, CIRP mediates inflammation and is a potential marker for synovial inflammation.	27315340
Pneumonitis, Eosinophilic inflammation	Altered Intercellular Communication	In mice inhalation of SplD without adjuvant induced lung inflammation characterized by TH2 cytokines and eosinophil infiltration.	27315768
Inflammation, Spinal Cord Injuries, Neuralgia	Altered Intercellular Communication	Targeting inflammation as a treatment modality for neuropathic pain in spinal cord injury: a randomized clinical trial.	27316678
Inflammation, Biliary calculi	Altered Intercellular Communication	However, on review by two different multidisciplinary teams, the final conclusion was probable residual gallstones with associated inflammation.	27317757
Inflammation, Malnutrition, Congestive heart failure	Altered Intercellular Communication	These observations support the complex involvement of malnutrition and inflammation in the pathogenesis of CHF.	27317841
Inflammation, Brain Injuries	Altered Intercellular Communication	Resveratrol attenuates peripheral and brain inflammation and reduces ischemic brain injury in aged female mice.	27318135
Infarction, Inflammation, Ischemic stroke	Altered Intercellular Communication	Mice treated with resveratrol demonstrated smaller infarct size, improved neurological function, and blunted peripheral inflammation at 3 days postischemic stroke.	27318135
Inflammation, Brain Injuries	Altered Intercellular Communication	These results showed that resveratrol counteracted inflammation in visceral adipose tissue and in the brain and reduced stroke-induced brain injury and peripheral inflammation in aged female mice.	27318135
Inflammation, AAVS1 gene, Vasculitis, CTCAE	Altered Intercellular Communication	Anti-neutrophil cytoplasmic antibody (ANCA) -associated vasculitis (AAV) is a disease characterized by inflammation of small vessels and detectable ANCA in the circulation.	27318367
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Stromal spindle cells such as fibroblasts are major components of tissue inflammation and tertiary lymphoid structures within the microenvironment that contribute to the survival and growth of cancer cells.	27318497
Inflammatory Bowel Diseases, Inflammation, gastrointestinal	Altered Intercellular Communication	Gastrointestinal and extraintestinal malignancies are long-term complications in patients with inflammatory bowel disease (IBD), likely as a result of chronic inflammation and the use of immunosuppressive medications used to control inflammation.	27318857
Inflammation	Altered Intercellular Communication	The impact of TREM-1-mediated inflammation was investigated in different inflammatory settings.	27319606
Sepsis, Communicable Diseases, Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	Systemic inflammation in humans may be triggered by infection, termed sepsis, or non-infective processes, termed non-infective systemic inflammatory response syndrome (SIRS).	27320175
Sepsis, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	Levels of these 'circulating inflammation-related microRNAs' (CIR-miRNAs) were 2.64 (IQR: 2.10-3.29) and 1.52 (IQR: 1.15-1.92) fold higher for non-infective SIRS and sepsis respectively (p < 0.0001), hence CIR-miRNAs appeared less abundant in sepsis than in SIRS.	27320175
Inflammation	Altered Intercellular Communication	CIR-miRNAs may be regulators of inflammation and warrant thorough evaluation as diagnostic and therapeutic targets.	27320175
Gingivitis, Chief complaint (finding)	Altered Intercellular Communication	The patient was a 66-year-old man who presented with the chief complaint of gingival inflammation and mobile teeth in the molar region.	27320299
Inflammation, Dental Plaque	Altered Intercellular Communication	Baseline examination revealed generalized plaque deposition and gingival inflammation.	27320300
palladium, Inflammation	Altered Intercellular Communication	After reducing inflammation and subgingival bacteria, open flap debridement was performed for teeth with a PD of >=4 mm.	27320300
ARCN1 gene, Inflammation	Altered Intercellular Communication	Acute exercise amplifies inflammation in obese patients with COPD.	27320704
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Systemic inflammation has been implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD) systemic effects.	27320704
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	However, most COPD patients do not suffer from persistent systemic inflammation even after exacerbations and exercise and scientific evidence has provided conflicting results.	27320704
ARCN1 gene, Inflammation, Obesity	Altered Intercellular Communication	This preliminary study did not show an enhanced inflammatory gene expression from rest to 1h and 24h after short-term exercise, but did show an increased inflammatory gene expression in both BMI extremes, both at rest and after exercise, suggesting not only malnourishment, but also obesity as potential links between COPD and systemic inflammation.	27320704
Inflammation, Atherosclerosis	Altered Intercellular Communication	The biochemical parameters for glucose metabolism, inflammation and atherosclerosis were determined.	27321876
Inflammation, physiopathological	Altered Intercellular Communication	Environmental enteric dysfunction (EED), a clinically asymptomatic condition characterized by inflammation of the small bowel mucosa, villous atrophy, and increased gut permeability, is common among children in developing countries.	27322559
Myositis	Altered Intercellular Communication	Our results indicate that osmolyte pathways may contribute to normal muscle functioning, and that activation of AR, TauT, and SMIT in muscle inflammation possibly contributes to the tissue's failing program of damage control.	27322952
Neoplasms, Cardiovascular Diseases	Altered Intercellular Communication	Final cytological and histological diagnoses were divided into 6 main diagnostic groups: normal, neoplasms (benign and malignant), inflammatory conditions, adaptive processes, degeneration, and cardiovascular disorders.	27322966
Chronic liver disease, Lymphoproliferative Disorder of the Skin, Necrosis with inflammation	Altered Intercellular Communication	Angiogenesis is generally induced in the process of necro-inflammation and regeneration in chronic liver diseases (CLD).	27323788
Inflammation, Colorectal Carcinoma, Dysbiosis	Altered Intercellular Communication	In conclusion, F. nucleatum, B. fragilis and F. prausnitzii can be identified as useful prognostic biomarkers for CRC, and dysbiosis might worsen the patients' prognosis by up-regulating gut inflammation level.	27323816
Malignant neoplasm of urinary bladder	Altered Intercellular Communication	Hormonal factors may play a role in bladder cancer (BCa).	27324053
Inflammation, Spinal Cord Injuries	Altered Intercellular Communication	Targeting inflammation to influence cognitive function following spinal cord injury: a randomized clinical trial.	27324320
Inflammation, Hippocampus (Brain)	Altered Intercellular Communication	Alternatively, as these participants likely underwent years of previous chronic inflammation, the underlying hippocampal damage may have negated potential improvements induced by acute reductions in inflammation.	27324320
Inflammation, Arthritis, Rheumatoid Arthritis	Altered Intercellular Communication	Ultrasound-detected subclinical inflammation was better reflected by the disease activity score (DAS-28) in patients with suspicion of inflammatory arthritis compared to established rheumatoid arthritis.	27325125
Refractory anemias, Inflammation, palladium, Superficial ulcer	Altered Intercellular Communication	Patients with RA in clinical remission had significantly more active inflammation and erosions on US when compared with patients with S-IA with similar disease scores (p = 0.03 and p = 0.01, respectively); however, RA patients with different disease activity score (DAS-28) scores had similar PD scores (p = 0.058).	27325125
Refractory anemias, Inflammation, Disease	Altered Intercellular Communication	Subclinical inflammation is more common in patients with RA in clinical remission or with low disease activity than in patients with S-IA; therefore, US was more useful in assessing for true remission in RA rather than diagnosing IA in patients with low disease activity scores.	27325125
Inflammation	Altered Intercellular Communication	Further research into validating this model can minimise the risk of underdiagnosing subclinical inflammation.	27325125
Peripheral zone of prostate, Prostate carcinoma	Altered Intercellular Communication	Peripheral Zone Inflammation Is Not Strongly Associated With Lower Urinary Tract Symptom Incidence and Progression in the Placebo Arm of the Prostate Cancer Prevention Trial .	27325488
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	Intraprostatic inflammation has been associated with lower urinary tract symptom (LUTS) progression.	27325488
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	We, therefore, evaluated inflammation and LUTS incidence and progression in men who underwent biopsy of the prostate peripheral zone irrespective of indication.	27325488
Inflammation	Altered Intercellular Communication	Inflammation prevalence in low cases (64%) was similar to controls (66%), but higher in moderate (69%) and high (73%) cases (P-trend = 0.4).	27325488
Inflammation, Lower Urinary Tract Symptoms	Altered Intercellular Communication	Peripheral zone intraprostatic inflammation is not strongly associated with LUTS incidence or progression.	27325488
Inflammation, Thrombophilia	Altered Intercellular Communication	Associations were not mediated by circulating levels of studied biomarkers suggesting that body size relates to VT because of physical factors associated with blood flow, not the hypercoagulability or inflammation associated with adiposity.	27328432
Inflammation, Hepatic Infection	Altered Intercellular Communication	The roles of TREM1 and sTREM1 in liver infection and inflammation are not clear.	27328755
Hepatitis	Altered Intercellular Communication	Trem1-/- mice showed accelerated clearance of LCMV-WE and manifested attenuated liver inflammation and injury.	27328755
Inflammation, Fibrosis Assessment, Complete atrioventricular block, Hepatitis B	Altered Intercellular Communication	A retrospective study to determine the relationships between platelet parameters and inflammation and fibrosis of the liver in patients with chronic hepatitis B virus infection (CHB).	27329384
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver fibrosis and inflammation were assessed by histopathology of biopsied liver tissue.	27329384
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The relationship between inflammation and fibrosis and platelet parameters were analysed by multiple linear regression.	27329384
Hepatitis	Altered Intercellular Communication	PLT and PDW accounted for 20.5% of liver inflammation.	27329384
Fibrosis Assessment, Hepatic inflammation	Altered Intercellular Communication	Platelet parameters can provide valuable information for the assessment of hepatic inflammation and fibrosis.	27329384
Rheumatoid Arthritis, Arteritis	Altered Intercellular Communication	Influence of triple disease modifying anti-rheumatic drug therapy on carotid artery inflammation in drug-naive patients with recent onset of rheumatoid arthritis.	27330160
Refractory anemias, vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Increased atherosclerosis in RA is not fully explained by the ordinary risk factors, but it may be related to vascular inflammation.	27330160
Refractory anemias, Arteritis	Altered Intercellular Communication	(18)F-FDG-PET/CT revealed that drug-naive patients with early RA show carotid artery inflammation that can be efficiently reduced by 1-month DMARD triple therapy.	27330160
Inflammation	Altered Intercellular Communication	Inflammation plays a major role in RD development after KPro implantation.	27330474
Inflammation	Altered Intercellular Communication	An association between gender, oxidative stress, and inflammation signaling exists, leading to a renewed interest in the neonate's sex as a potential risk factor to several alterations.	27331351
Immunologic Deficiency Syndromes, Granulomatous inflammation, Chronic granulomatous disease, Infection	Altered Intercellular Communication	Chronic granulomatous disease is a rare, inherited immunodeficiency disorder that reduces the superoxide generation ability of phagocytes, leading to recurrent infections and granulomatous inflammation.	27331854
Sjogrens Syndrome	Altered Intercellular Communication	Epigenetic Signatures of Salivary Gland Inflammation in Sjogren's Syndrome.	27332624
Inflammation, Atrophic	Altered Intercellular Communication	Histological neutrophil activity, chronic inflammation and atrophy scores were lower in group A' than in other groups.	27332718
Sepsis, Communicable Diseases	Altered Intercellular Communication	It also distinguished infection from trauma-related inflammation in the same patient cohorts with a higher specificity than the clinical sepsis biomarker, C-reactive Protein.	27333027
Arthritis, Dysbiosis	Altered Intercellular Communication	Autoreactive SKG mouse T cells are activated by dysbiotic microbiota in the intestine, causing joint inflammation.	27333153
Dermatitis, Atopic, Eyelid malposition, Inflammation, Lacrimation	Altered Intercellular Communication	Allergic dermatitis is a common but often misdiagnosed condition that can present with a variety of findings including inflammation, eyelid malposition, and tearing.	27333449
Inflammation	Altered Intercellular Communication	Topical corticosteroids often facilitate resolution of the associated inflammation.	27333449
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Lung diseases	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a progressive pulmonary disease characterized by systemic inflammation.	27333717
Inflammation, neurological disability, Nerve Degeneration	Altered Intercellular Communication	Inflammation is tightly linked with neurodegeneration, and it is the accumulation of neurodegeneration that underlies increasing neurological disability in progressive MS.	27333900
Infection caused by Helicobacter pylori, Duodenal Diseases	Altered Intercellular Communication	Polymorphisms in inflammation-related genes are factors associated with the development of gastroduodenal diseases in Helicobacter pylori-infected individuals.	27334226
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	The impact of metabolic syndrome (MetS) associated systemic inflammation on the male reproductive tract requires further investigation.	27334450
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	The results suggest that MetS is associated with decreased fertility parameters in males, as well as local reproductive tract inflammation, in the absence of leukocytospermia.	27334450
Inflammatory Bowel Diseases, Bacterial Infections, Gastrointestinal inflammation	Altered Intercellular Communication	Fecal calprotectin (fc) is a sensitive marker of intestinal inflammation, found to be associated with enteric bacterial infections and inflammatory bowel disease.	27334992
Inflammation	Altered Intercellular Communication	Our results suggest that exposure to pollutants with high oxidative potential (traffic-related pollutants, ultrafine particles, and transition metals) may lead to increased airway oxidative stress and inflammation in elderly adults.	27336235
Obesity	Altered Intercellular Communication	Does Inflammation Mediate the Obesity and BPH Relationship?	27336586
Obesity, prostatitis	Altered Intercellular Communication	Our objective was to investigate biomarkers of systemic and prostate tissue inflammation as potential mediators of the obesity and BPH association.	27336586
Inflammation, Lower Urinary Tract Symptoms, prostatitis	Altered Intercellular Communication	In contrast, the severity of prostate tissue inflammation was significantly associated with LUTS, such that there was a 7 point difference in AUA-SI between men with mild vs. severe inflammation (p = 0.004).	27336586
Lower Urinary Tract Symptoms, prostatitis	Altered Intercellular Communication	Additionally, men with a greater waist-hip ratio (WHR) were significantly more likely to have severe prostate tissue inflammation (p = 0.02), and a high WHR was significantly associated with moderate/severe LUTS (OR = 2.56, p = 0.03) among those participants with prostate tissue inflammation.	27336586
Inflammation, Lower Urinary Tract Symptoms, Obesity	Altered Intercellular Communication	The WHR, an estimate of centralized obesity, was associated with the severity of inflammatory regions in prostate tissue and with LUTS severity among men with inflammation.	27336586
Inflammation, Increase, Obesity	Altered Intercellular Communication	Our results suggest centralized obesity advances prostate tissue inflammation to increase LUTS severity.	27336586
Inflammation, altretamine/doxorubicin/melphalan protocol, Tropical Spastic Paraparesis	Altered Intercellular Communication	Five to ten million persons, are infected by HTLV-1 of which 3% will develop HTLV-1-associated myelopathy (HAM) a chronic, disabling inflammation of the spinal cord.	27336911
Airway structure, Inflammation	Altered Intercellular Communication	Nitric oxide (NO) is marker of inflammation, and fractional exhaled NO (FeNO) is a marker of airway inflammation.	27337107
Ichthyosis Bullosa of Siemens, Viscero-Visceral Reflex, Urinary Calculi, Irritable Bowel Syndrome	Altered Intercellular Communication	The neurotransmitter pathways in irritable bowel syndrome (IBS) and urinary stone attacks are both related to serotonin, and each disease may be influenced by viscero-visceral hyperalgesia.	27337114
Inflammation	Altered Intercellular Communication	Median ferritin concentrations (adjusted for inflammation) ranged between 48 and 91 mg/L among Cambodian women and between 54 and 55 mg/L among Congolese children.	27337742
Central Serous Chorioretinopathy	Altered Intercellular Communication	The results revealed signs of Central Serous Chorioretinopathy in both eyes which may have been due to various hormonal changes in pregnancy with resultant changes in refractive error.	27337860
Inflammation, Fibrosis Assessment, Hypoxia	Altered Intercellular Communication	Compared to IMA-PVAT, C-PVAT exhibited more pronounced angiogenesis and inflammation, as indicated by significantly higher numbers of PECAM1-positive vessels and CD68-positive macrophages, and was characterized by a greater extent of fibrosis and hypoxia.	27337945
Inflammation, Fibrosis Assessment, Hypoxia, Plaque, Atherosclerotic	Altered Intercellular Communication	A higher degree of local tissue hypoxia and up-regulation of leptin expression in the perivascular adipose tissue, along with increased vascularization, inflammation, and fibrosis, may contribute to the increased atherosclerotic plaque burden in the coronary arteries compared to the IMA.	27337945
Refractory anemias, Inflammation, Obesity	Altered Intercellular Communication	The dominance of obesity in females and the different behaviour of disease activity markers in relation to the BMI in females indicate that additional parameters need to be considered when analysing the impact of obesity on inflammation in RA.	27338263
Inflammation, Cerebral Edema	Altered Intercellular Communication	Substance P (SP), a member of tachykinin family, is involved in the inflammation of the central nervous system and in the appearance of cerebral edema.	27338372
Airway structure	Altered Intercellular Communication	PMcoarse was associated with an increase in FENO, indicating sub-clinical airway inflammation in healthy children.	27338437
Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	Emerging studies suggest that in neurodegenerative diseases, aggregation of one protein species can promote other proteinopathies and that inflammation plays an important role in this process.	27339073
Inflammation	Altered Intercellular Communication	Histopathology of the lung tissue revealed acute and chronic inflammation.	27339583
Peptide Hydrolases, Inflammation	Altered Intercellular Communication	Proteolytic damage or inflammation of the vessels may also play a significant part.	27339635
Multiple polyps, Inflammation, Superficial ulcer, Pathology, Ulcer	Altered Intercellular Communication	Ulcers, inflammation and erosions (13%), polyposis syndromes (9.8%) and vascular pathologies (7.4%) were the most common endoscopic findings.	27339642
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation and Progression of CKD: The CRIC Study.	27340285
Alzheimers Disease	Altered Intercellular Communication	Folic Acid Supplementation Mitigates Alzheimer's Disease by Reducing Inflammation: A Randomized Controlled Trial.	27340344
Inflammation, Data types - Address	Altered Intercellular Communication	Inflammation may play an important role in the interaction between folic acid and AD.	27340344
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Biopsies were also assessed for inflammation and fibrosis, and for the association of SM levels with liver volume, liver function tests, and lipid profiles.	27340749
Inflammation, Myeloproliferative disease, Hematologic Neoplasms	Altered Intercellular Communication	It has been shown that angiogenesis and inflammation play an important role in development of most hematological malignancies including the myeloproliferative neoplasm (MPN).	27341002
Inflammation, Intracranial Aneurysm	Altered Intercellular Communication	Aneurysmal wall enhancement (AWE) has emerged as a new possible biomarker for depicting inflammation of the intracranial aneurysm (IA).	27341856
Inflammation, Pain Distress Question	Altered Intercellular Communication	BACKGROUND Inflammation is considered as one of the main pathogeneses in OA-induced pain.	27342658
Inflammation, Refractory anemias, Autoimmune Diseases, Rheumatoid Arthritis, Erosion of bone	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a systemic autoimmune disease resulting in chronic inflammation of the synovium and consequent cartilage and bone erosion.	27342690
Refractory anemias, Hyperplasia	Altered Intercellular Communication	PGK1, a glycolytic enzyme catalyzing the conversion of 3-phosphoglycerate into 2-phosphoglycerate, has increased expression in synovial tissues and blood of RA, which may be involved in pro-inflammation and synovial hyperplasia of the disease.	27342824
Inflammation	Altered Intercellular Communication	The early inflammation reaction to rhBMP-2 manifesting with radicular symptoms has been previously reported in patients undergoing transforaminal lumbar interbody fusion (TLIF).	27343729
Inflammation	Altered Intercellular Communication	Inflammation-associated lymphangiogenesis (IAL) has been identified as part of several acute and chronic inflammation.	27344132
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Association of novel metrics of particulate matter with vascular markers of inflammation and coagulation in susceptible populations -results from a panel study.	27344265
Inflammation	Altered Intercellular Communication	Epidemiological studies have shown adverse effects of ambient air pollutants on health with inflammation and oxidative stress playing an important role.	27344265
Diabetic Nephropathy, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	Greater renal function decline (RFD) in type 2 diabetes (T2DM) has been suggested in men compared with women, and imbalances in estrogen/androgen levels have been associated with cardiovascular disease mortality in elderly men, but it remains unclear whether sex hormone disequilibrium is related to diabetic nephropathy (DN) in men with T2DM.	27344412
ARCN1 gene, Inflammation, AHR wt Allele, Chronic Obstructive Airway Disease, Asthma	Altered Intercellular Communication	The impact of airway hyperreactivity (AHR) on respiratory mortality and systemic inflammation among patients with chronic obstructive pulmonary disease (COPD) is largely unknown.	27345171
Inflammation, Malnutrition	Altered Intercellular Communication	The predictive value of malnutrition - inflammation score on 1-year mortality in Turkish maintenance hemodialysis patients.	27345184
Inflammation, Hemorrhage, Meckel Diverticulum, Obstruction	Altered Intercellular Communication	The most common complications of Meckel's diverticulum are inflammation, bleeding and obstruction.	27345602
Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Hormonal milieu has long been known to play an important role in the development of type 2 diabetes (T2D).	27345735
Fibrous, Fibrous stenosis	Altered Intercellular Communication	Inflammation-dominant stenosis (type 1) was found in 8.9% of the patients, web-associated fibrous stenosis (type 2) in 19.5%, and fibrous (type 3) in 71.6%.	27346484
Inflammation, Pseudoaneurysm	Altered Intercellular Communication	In some cases, infected pseudoaneurysms can be masked by the excessive inflammation of surrounding tissues.	27346681
Inflammation, Infection, Anemia	Altered Intercellular Communication	High RBC EPA status, inflammation and infections, and lower education levels may contribute to the prevalence of anaemia in this population, which is not related to iron status.	27348115
Inflammation	Altered Intercellular Communication	The serum TB may play a crucial role in inflammatory by contributing to inhibit the inflammation effect.	27349017
Inflammation, Kit Ligand, human, Atherosclerosis	Altered Intercellular Communication	Several lines of evidence suggest that slow coronary flow (SCF) phenomenon seems to be an early form of atherosclerosis and low-grade inflammation plays a role in the development of SCF.	27349023
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	The formation of monocyte-platelet aggregates and neutrophil-platelet aggregates (MPA and NPA, respectively) is influenced by inflammation, but also might contribute to an exacerbation of inflammatory responses in atherosclerotic plaque.	27352829
Mastitis, Inflammation, Edema	Altered Intercellular Communication	In cases of mastitis with abscess formation, there is a characteristic appearance, with a central very soft area (abscess cavity) and a very stiff outer rim (edema and inflammation).	27353071
Inflammation, Calcified (qualifier), Calcinosis, Diabetes Mellitus	Altered Intercellular Communication	Histopathological assessment of calcification and inflammation of calcific aortic valves from patients with and without diabetes mellitus.	27353274
Inflammation, Calcinosis	Altered Intercellular Communication	Inflammation and calcification were assessed by immunohistochemistry and immunofluorescence staining.	27353274
Inflammation, Calcinosis, diabetic	Altered Intercellular Communication	Aortic valves from diabetic patients show more calcification, while inflammation is similar in both patient populations.	27353274
Calcinosis, Congenital bilateral aplasia of vas deferens, diabetic	Altered Intercellular Communication	Considering the generally accepted theory of an inflammation-dependent mechanism of calcification, these data suggest that in patients with CAVD requiring valve replacement, diabetic patients could be molecularly in a more advanced disease stage with a higher grade of mineralization than non-diabetic patients.	27353274
helium, Inflammation	Altered Intercellular Communication	Electrolyte abnormalities and mild inflammation are involved in the pathogenesis of HE.	27353278
Inflammation, Stomach ache, Diarrhea, Dyspepsia, Digestive System Disorders, Constipation	Altered Intercellular Communication	These medicinal plant species were used commonly as an ethno medicine against 26 various digestive disorders out of which most frequently occurred are; stomach ache, diarrhea, indigestion, constipation and inflammation etc.	27353866
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Appendiceal orifice inflammation is associated with proximal extension of disease in patients with ulcerative colitis.	27354363
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is considered to be a disease of continuous mucosal inflammation extending proximally from the rectum.	27354363
Inflammation	Altered Intercellular Communication	However, appendiceal orifice inflammation (AOI) is a skip lesion with segments of continuous involvement from the rectum.	27354363
Inflammation, Edema	Altered Intercellular Communication	The degree of AOI was graded endoscopically as follows: 0 (no inflammation); 1 (slight oedema); 2 (moderate inflammation); and 3 (marked inflammation).	27354363
Proctitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Our results showed correlations between AOI and subsequent proximal extension of mucosal inflammation in patients with proctitis.	27354363
Inflammation	Altered Intercellular Communication	Increasing mGPS (systemic inflammation) and deteriorating PS were associated with deterioration in quality-of-life parameters (P < .001).	27354484
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Systemic inflammation was associated with quality-of-life parameters independent of PS in patients with advanced cancer.	27354484
Inflammation, Observation Method - Coagulation, Blood Coagulation Disorders, platelet dysfunction	Altered Intercellular Communication	Trauma-associated coagulopathy is a complex process involving inflammation, coagulation, and platelet dysfunction.	27355402
Hypermetabolism, Burn Specimen Source Codes, Inflammation, Hyperglycemia	Altered Intercellular Communication	Inflammation and hypermetabolism post burn predisposes to hyperglycemia and insulin resistance.	27355659
Inflammation, Subarachnoid Hemorrhage, Cerebral Ischemia	Altered Intercellular Communication	Considering the important role of inflammation in the pathogenesis of delayed cerebral ischaemia, we investigated whether matrix metalloproteinase-9 (MMP-9) may be an efficient biomarker for predicting elayed cerebral ischaemia after subarachnoid haemorrhage.	27355865
Thrombosis	Altered Intercellular Communication	Humoral autoimmune-mediated inflammation plays a role in atherogenesis, and potentially in arterial thrombosis.	27356567
Inflammation	Altered Intercellular Communication	Bacteria of leg atheromatous arteries responsible for inflammation.	27356591
Ischemia, Inflammation, Necrosis	Altered Intercellular Communication	Ischaemia of the lower limbs is frequently followed by inflammation and, in advanced cases, necrosis of peripheral tissues.	27356591
Inflammation, Ischemic	Altered Intercellular Communication	They may predispose to inflammation secondary to ischaemic changes.	27356591
Inflammation, Hepatitis, Alcoholic	Altered Intercellular Communication	The damage-associated molecular pattern HMGB1 is elevated in human alcoholic hepatitis, but does not seem to be a primary driver of inflammation.	27357188
Inflammation, Moist, Hepatitis, Alcoholic	Altered Intercellular Communication	The role of sterile inflammation caused by release of damage-associated molecular patterns (DAMP) remains unclear in human alcoholic hepatitis (AH).	27357188
Tissue damage, Inflammation, Moist	Altered Intercellular Communication	The DAMP, high mobility group box-1 protein (HMGB1) is released by tissue damage and inflammation.	27357188
Inflammation	Altered Intercellular Communication	This combined with an increased TLR4 expression, but an unaffected cytokine response to HMGB1 suggest that HMGB1 is not the primary driver of inflammation in AH.	27357188
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Inflammation is becoming increasingly recognized as an important contributor to Alzheimer's disease (AD) pathogenesis.	27357286
APP gene, Inflammation	Altered Intercellular Communication	AAA is caused by segmental weakening of the aortic walls and progressive aortic dilation leading to the eventual rupture of the aorta, accompanied by intense inflammation.	27358138
IgG4-Related Sclerosing Disease	Altered Intercellular Communication	IgG4-related disease (IgG4-RD) is a chronic, systemic, inflammatory condition of unknown aetiology.	27358392
Inflammation	Altered Intercellular Communication	Metabolic inflammation contributes to the development of insulin resistance (IR), but the roles of different inflammatory and other cytokines in this process remain unclear.	27362289
Pain Distress Question, Conjunctivitis	Altered Intercellular Communication	Pain was significantly relieved, conjunctival inflammation was markedly resolved, and the central descemetocele area became thicker with scar formation in all patients.	27362878
Scleritis, Orbital Pseudotumor, Exacerbation of cGVHD	Altered Intercellular Communication	Two of 11 (18%) patients on rituximab had flares of scleritis and orbital inflammation but not PUK.	27362884
Inflammation, Fibrosis Assessment, Intrahepatic bile duct	Altered Intercellular Communication	Compared with the malignant group, patients in the benign group were more likely to show severe periportal inflammation in noninvolved liver (P < 0.001), fibrosis around intrahepatic bile duct (P < 0.001), and more IgG4-positive plasma cells (P < 0.001) on liver pathology.	27363632
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Immune cell-mediated inflammation is an essential process for mounting a repair response after myocardial infarction (MI).	27364164
Inflammation, Fibrosis Assessment, Hyperplastic Polyp, muscle hyperplasia, Hypertrophy	Altered Intercellular Communication	For each layer of bowel wall (mucosa including muscularis mucosae [MU], submucosa [SM], muscularis propria [MP], subserosal adventitia [SS]), histological abnormalities were evaluated individually, including active and chronic inflammation, fibrosis, smooth muscle hyperplasia or hypertrophy, neuronal hypertrophy and adipocyte proliferation.	27364949
Inflammation, Subject Disease Milestones Domain, Hyperplastic Polyp, muscle hyperplasia, Hypertrophy	Altered Intercellular Communication	The most significant histopathological features characterizing the stricturing intestines were smooth muscle hyperplasia of SM, hypertrophy of MP and chronic inflammation.	27364949
Fibrosis Assessment, Hypertrophy and Hyperplasia, Chronic inflammation, Fibromuscular Dysplasia	Altered Intercellular Communication	The overall muscular hyperplasia/hypertrophy was positively correlated with chronic inflammation and negatively correlated with fibrosis, whereas SM muscular hyperplasia was also associated with MU active inflammation.	27364949
Crohn Disease, muscle hyperplasia	Altered Intercellular Communication	The 'inflammation-smooth muscle hyperplasia axis' may be the most important in the pathogenesis of Crohn's strictures.	27364949
Inflammation, Metabolic Diseases	Altered Intercellular Communication	This association is partially mediated by metabolic disorders and inflammation.	27365403
Hepatitis, Obesity	Altered Intercellular Communication	The role of NK cells in visceral adipose tissue (VAT) and liver inflammation in obesity is not fully understood.	27365528
Inflammation, physiopathological, ETV3 wt Allele, Metabolic Syndrome X	Altered Intercellular Communication	One of the pathophysiologies in the development of DES is inflammation, and metabolic syndrome (MetS), which is highly prevalent in the general population, is a well-known chronic and systemic inflammatory condition.	27366012
Inflammation, physiopathological, ETV3 wt Allele, Metabolic Syndrome X	Altered Intercellular Communication	One of the pathophysiologies in the development of DES is inflammation, and metabolic syndrome (MetS), which is highly prevalent in the general population, is a well-known chronic and systemic inflammatory condition.	27366012
Inflammation, Dryness of eye, PEELING SKIN SYNDROME	Altered Intercellular Communication	HCQ at 300 mg daily for 12 weeks has no apparent clinical benefit for dry eye and systemic inflammation in pSS (ClinicalTrials.gov.	27366013
Inflammation, Primary malignant neoplasm, Hypersensitivity	Altered Intercellular Communication	Despite its important role in allergies and inflammation, little is known about how extracellular TCTP affects cancer progression.	27367023
Inflammation, Loneliness, Depression, CTCAE, Atherosclerosis	Altered Intercellular Communication	Loneliness, Depression, and Inflammation: Evidence from the Multi-Ethnic Study of Atherosclerosis.	27367428
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Since Sirt1 activity is known to be affected by several stresses, including inflammation and oxidative stress, as well as aging, SIRT may be involved in the development of OA.	27367673
Inflammation, Acute otitis media	Altered Intercellular Communication	Conventional treatment for acute otitis media mainly targets bacteria with antibiotics, neglecting to control for mediators of inflammation.	27368439
Inflammation, Acute otitis media, Otitis Media with Effusion, Infectious Otitis Media	Altered Intercellular Communication	Mediators of inflammation, such as leukotrienes, have been identified in patients with acute otitis media (AOM) or subsequent secretory otitis media (SOM).	27368439
Inflammation, Infectious Otitis Media	Altered Intercellular Communication	The results indicate that combined treatment of AOM with antibiotics and a leukotriene antagonist to control inflammation is useful for preventing progression to persistent SOM.	27368439
Pelvic Inflammatory Disease	Altered Intercellular Communication	We presume that-in the present case-the expansive capacity of the uterine wall may have been reduced after the series of severe pelvic inflammations.	27370269
Inflammation	Altered Intercellular Communication	Inflammation induced by the activation of cytokines and neuropeptides is implied in its pathophysiology.	27371188
Inflammation, Migraine Disorders, Atherosclerosis	Altered Intercellular Communication	There is an association between inflammation and atherosclerosis in patients with migraine.	27371188
Migraine Disorders, Inflammation, Atherosclerosis	Altered Intercellular Communication	In children with migraine, an evaluation of CIMT can be used as a non-invasive imaging modality to detect atherosclerosis, which develops in the context of chronic inflammation.	27371188
Hyperglycemia, Inflammation, Impaired cognition	Altered Intercellular Communication	Hyperglycemia, inflammation, and oxidative stress are thought to be involved in the pathogenesis of cognitive decline.	27371673
Inflammation	Altered Intercellular Communication	The mechanisms might be partly explained by the effect of DPP4 on inflammation and oxidative stress.	27371673
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	It is a systemic vasculitis characterized by diffuse inflammation of medium and small blood vessels.	27371760
Inflammation	Altered Intercellular Communication	There was no association between inflammation and rate of hip BMD loss.	27371811
Inflammation, Fracture	Altered Intercellular Communication	We conclude that inflammation may play an important role in the etiology of fractures in older men.	27371811
Inflammation, Fibrosis Assessment, Traumatic injury	Altered Intercellular Communication	Delayed changes include a tissue response consisting of inflammation, fibrosis and neo-osteogenesis induced by trauma and an immunologic reaction to a foreign body.	27371868
Inflammation, Kidney Failure, Acute, Endothelial dysfunction	Altered Intercellular Communication	All biomarkers of inflammation and endothelial dysfunction were associated with AKI.	27372077
Inflammation, Kidney Failure, Acute, Critical Illness	Altered Intercellular Communication	In critically ill patients, plasma concentration of the endothelial growth factors Ang-1 and Ang-2 are associated with AKI, independently of inflammation.	27372077
Inflammation, Arthritis, Psoriatic	Altered Intercellular Communication	Active peripheral inflammation is associated with pro-atherogenic lipid profile in psoriatic arthritis.	27373499
Arthritis	Altered Intercellular Communication	Our findings suggest an association between peripheral joint inflammation and lipid dysregulation in PsA.	27373499
Glaucoma, CTCAE, Optic Neuritis	Altered Intercellular Communication	Optic neuritis (ON) is unilateral painful optic nerve inflammation in a young healthy female diagnosed by excluding glaucoma.	27373939
Inflammation, Malnutrition	Altered Intercellular Communication	It reduces burden of inflammation and malnutrition and this effect may cause beneficial effect on HR-QoL.	27374393
Neuromyelitis Optica, N-nitrosomorpholine	Altered Intercellular Communication	Neuromyelitis optica (NMO) is a rare neuro-inflammatory condition characterized by acute relapses causing severe visual or physical disability.	27374494
Inflammation, Communicable Diseases, Diabetic Foot, Ulcer, Empyema, Pleural	Altered Intercellular Communication	NPWT has a fixed role in the treatment of stage IV pressure ulcers at sacrum or ischium, pyothorax, infection and inflammation because of internal joint prosthesis or an internal fixation device and diabetic foot syndrome.	27374835
Infection	Altered Intercellular Communication	Every fourth to fifth case hospitalised for disruption of surgical wounds or infections following a procedure (241%), as well as for infections and inflammations because of internal joint prosthesis or because of an internal fixation device was treated with NPWT (229%).	27374835
Adrenal mass, Malignant Neoplasms	Altered Intercellular Communication	Discovery of an adrenal mass needs further evaluation in order to exclude malignancy and hormonal secretion.	27376430
Inflammation, Pituitary Gland	Altered Intercellular Communication	Significant pituitary mass reduction with regression of the inflammation to the cavernous sinuses was documented.	27376431
Inflammation	Altered Intercellular Communication	Faecolith is an extremely rare cause of acute inflammation of the caecum presenting as a mass which is usually treated by limited right hemicolectomy.	27377227
Inflammation, Neoplasms	Altered Intercellular Communication	This suggests an environmental field effect that promotes multiple tumours likely in the background of inflammation.	27377421
Inflammation	Altered Intercellular Communication	We may say that the improvement of the above parameters could reduce inflammation and oxidative stress and vascular damages what would extend life expectancy and quality of life of this group of patients.	27377683
Airway structure, Pseudomonas aeruginosa, Colonization	Altered Intercellular Communication	Colonization of CF patients' upper airways with S. aureus contributes more decisively to upper airway inflammation than P. aeruginosa.	27377929
Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	Chronic Prostate Inflammation is Associated with Severity and Progression of Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms and Risk of Acute Urinary Retention.	27378134
Inflammation, Prostate carcinoma, Benign prostatic hypertrophy	Altered Intercellular Communication	The association of acute and chronic inflammation detected on baseline biopsies and benign prostatic hyperplasia related parameters, including I-PSS (International Prostate Symptom Score) and prostate volume, at multiple time points during 4 years in men randomized to placebo enrolled in the REDUCE prostate cancer prevention study was analyzed with the Student t-test.	27378134
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	The association of inflammation with newly developed benign prostatic hyperplasia/lower urinary tract symptoms and benign prostatic hyperplasia progression in patients with existing benign prostatic hyperplasia/lower urinary tract symptoms was analyzed with univariable and multivariable Cox models.	27378134
Inflammation	Altered Intercellular Communication	Acute and chronic inflammation was seen in baseline negative biopsies of 641 (15.6%) and 3,216 (78.3%) of the 4,109 men in the study.	27378134
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	The presence of acute and chronic inflammation was not associated with the incidence of benign prostatic hyperplasia/lower urinary tract symptoms in men without those conditions at baseline or the progression of symptomatic benign prostatic hyperplasia in men with benign prostatic hyperplasia/lower urinary tract symptoms at baseline.	27378134
Inflammation	Altered Intercellular Communication	Chronic inflammation at baseline was associated with an increased risk of acute urinary retention (HR 1.6-1.8, p = 0.001).	27378134
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Our longitudinal evaluation of REDUCE patients randomized to placebo for 4 years confirmed that chronic inflammation is associated with severity and the progression of benign prostatic hyperplasia and benign prostatic hyperplasia/lower urinary tract symptom outcomes.	27378134
Inflammation, Atherosclerosis	Altered Intercellular Communication	Increasing evidence suggests that inflammation and increased macrophage activity have a central role in pathogenesis of atherosclerosis.	27378685
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	Altogether, our data indicate that IP3R2 protects against the negative effects of inflammation, suggesting that the increase in IP3R2 expression in ALS patients is a protective response.	27378687
Inflammation, Rheumatic Fever, Coronary Artery Disease	Altered Intercellular Communication	Plasma vitamin D levels and inflammation in the aortic wall of patients with coronary artery disease with and without inflammatory rheumatic disease.	27379927
Inflammation, Interferon-Related DNA Damage Resistance Gene Signature, Coronary Artery Disease, Inflammatory disorder	Altered Intercellular Communication	Vitamin D modulates inflammation, and this may explain the observed associations between vitamin D status and disorders driven by systemic inflammation, such as coronary artery disease (CAD) and inflammatory rheumatic diseases (IRDs).	27379927
Inflammation, Malignant neoplasm of larynx	Altered Intercellular Communication	Besides tobacco and alcohol, diet and inflammation have been suggested to be important risk factors for laryngeal cancer.	27379989
Inflammation, Malignant neoplasm of larynx	Altered Intercellular Communication	In this study, we examined the role of diet-associated inflammation, as estimated by dietary inflammatory index (DII) scores, in laryngeal cancer in a multicentre case-control study conducted between 1992 and 2000 in Italy.	27379989
Intraocular inflammation	Altered Intercellular Communication	Main outcome measures were changes in visual acuity, intraocular inflammation, concomitant immunosuppressive drug or intravitreal steroid, and adverse events.	27380253
Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation was controlled in 10 of 14 patients (71%) at 1 year, with a mean dose of 6.2 mg/day prednisone.	27380253
Viremia	Altered Intercellular Communication	Cytomegalovirus viremia was detected in 16 (72.7%) of the 22 patients with inflammation-associated complications.	27380428
Inflammation, Heart failure	Altered Intercellular Communication	Heart failure is associated with low-grade inflammation.	27380510
Inflammation, Heart failure	Altered Intercellular Communication	In the present study we sought to assess the prognostic impact of orosomucoid, a marker of inflammation, in outpatients with heart failure.	27380510
Low Back Pain, Inflammation	Altered Intercellular Communication	Inflammation in low back pain may be detected from the peripheral blood: suggestions for biomarker.	27380953
Inflammation, Neurogenic Inflammation, Pain Distress Question	Altered Intercellular Communication	In the present study, we examined evidence of inflammation in the peripheral blood and demonstrated significant changes in neuroinflammation markers in subjects with chronic low back pain in comparison with control subjects.	27380953
Intraocular inflammation, Primary intraocular non-Hodgkin malignant lymphoma, Uveitis	Altered Intercellular Communication	To present challenging cases of vitreoretinal lymphoma (VRL) that was misdiagnosed as uveitis because of the apparent intraocular inflammation.	27380976
Idiopathic Inflammatory Myopathies	Altered Intercellular Communication	VRLs are severe diseases with a poor prognosis that may be misdiagnosed as idiopathic inflammatory conditions of the eye.	27380976
Tears body substance, Pain Distress Question, Inflammation, Calcific tendinitis	Altered Intercellular Communication	The lifetime prevalence of shoulder pain approaches 70%, which is mostly attributable to rotator cuff lesions such as inflammation, calcific tendinitis and tears.	27381057
Tears body substance, Inflammation, Calcific tendinitis	Altered Intercellular Communication	The collected cases included 43 cases of inflammation, 30 cases of calcific tendinitis and 26 tears.	27381057
Tears body substance, Inflammation, Calcific tendinitis	Altered Intercellular Communication	The individual accuracy of this CAD system was 88.4% for inflammation, 83.3% for calcific tendinitis and 92.3% for tears.	27381057
Inflammation, Toxicity Tests, Acute	Altered Intercellular Communication	Thus, a proportion of acute urinary toxicity in men with an intact prostate may be attributable to inflammation of the prostatic gland or urethra.	27381895
Inflammation, Middle-aged men, Fatigue	Altered Intercellular Communication	Relationship of Objectively-Measured Habitual Physical Activity to Chronic Inflammation and Fatigue in Middle-Aged and Older Adults.	27382039
Inflammation, Fatigue	Altered Intercellular Communication	Habitual (non-exercise) physical activity (PA) declines with age, and aging-related increases in inflammation and fatigue may be important contributors to variability in PA.	27382039
Inflammation, Weight decreased, Fatigue	Altered Intercellular Communication	At the 18-month follow-up, inflammation was lower in both weight loss groups, fatigue was reduced in all three groups with larger decreases in the combined group, and mean levels of habitual PA were not changed in any group.	27382039
Inflammation, Fatigue	Altered Intercellular Communication	Levels of habitual PA are lower in middle-aged and older adults with higher levels of chronic inflammation and greater self-reported fatigue.	27382039
Inflammation, Fatigue	Altered Intercellular Communication	In addition, participants who experienced greater declines in inflammation during the interventions had greater declines in fatigue and larger increases in PA.	27382039
Inflammation	Altered Intercellular Communication	Together, these results establish that vagus nerve stimulation targeting the inflammatory reflex modulates TNF production and reduces inflammation in humans.	27382171
Arthritis	Altered Intercellular Communication	One well-characterized cytokine-inhibiting mechanism, termed the "inflammatory reflex," is dependent upon vagus nerve signals that inhibit cytokine production and attenuate experimental arthritis severity in mice and rats.	27382171
Inflammation	Altered Intercellular Communication	Vaspin is a novel adipocytokine associated with glucose tolerance and chronic inflammation.	27383120
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	After treatment, the sinonasal skull base is predisposed to prolonged inflammation that may render this time-point inappropriate for initial posttreatment imaging surveillance for sinonasal malignancies.	27383662
Granulomatous inflammation	Altered Intercellular Communication	To determine the proportional distribution of endobronchial tuberculosis (EBTB) subtypes and to evaluate the types of bronchoscopic diagnostic procedures that can prove granulomatous inflammation.	27383932
Granulomatous inflammation	Altered Intercellular Communication	Among the 18 patients with EBTB, granulomatous inflammation was proven by the following bronchoscopic diagnostic procedures: bronchial mucosal biopsy, in 8 (44.4%); bronchial brushing, in 7 (38.8%); fine-needle aspiration biopsy, in 2 (11.1%); and BAL, in 2 (11.1%).	27383932
Inflammation, hafnium, Depression, CTCAE	Altered Intercellular Communication	In addition, it examined whether there was a mediating relationship between social support and marital status and whether depression and inflammation influenced one another to predict mortality of HF patients.	27384414
Inflammation	Altered Intercellular Communication	Monitoring chronic HF patients who are unmarried, with elevated inflammation, or in higher NYHA class may help identify those at greater mortality risk to implement targeted intervention.	27384414
Inflammation, Gastric Cardia Carcinoma	Altered Intercellular Communication	These findings provide pathological evidence that H. pylori infectionis a driving force of gastric cardia carcinogenesis by upregulating CDX2 and inducing inflammation.	27384681
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Thrombin generation assay: interactions between chronic inflammation and haemostasis in patients with autoimmune diseases.	27385196
Inflammation, Anemia	Altered Intercellular Communication	Fixed dose of long-acting erythropoietic stimulating agents at higher frequency improves appetite, reduces inflammation and corrects anaemia in patients on haemodialysis.	27385380
Inflammation, Anemia	Altered Intercellular Communication	We demonstrate that a fixed monthly dose of CERA at a twice monthly dosing schedule improves nutrition, reduces the inflammation and corrects anaemia in patients on haemodialysis.	27385380
vascular inflammations, Endothelial dysfunction	Altered Intercellular Communication	However, involvement of vascular inflammation in endothelial dysfunction is not fully investigated in humans because of the lack of diagnostic modality to noninvasively evaluate vascular inflammation.	27386941
Inflammation, Neuropathy	Altered Intercellular Communication	Neuropathy per se may lead to skin inflammation.	27387067
Inflammation, Orbital Fractures	Altered Intercellular Communication	Delayed onset porous polyethylene implant-related inflammation after orbital blowout fracture repair: four case reports.	27387333
Inflammation	Altered Intercellular Communication	Delayed inflammation related to porous polyethylene sheet implants is very rare and no case series of this condition have been reported.	27387333
Inflammatory	Altered Intercellular Communication	Chronic and subacute orbital inflammatory signs were noted in two patients and acute fulminant orbital inflammation was found in two patients.	27387333
Inflammation	Altered Intercellular Communication	Low-grade or fulminant inflammation could complicate blowout fracture repair related with the implant.	27387333
Inflammation, Pain Distress Question	Altered Intercellular Communication	Aseptic loosening (AL) of hip prosthesis presents inflammation and pain as sign and symptom similarly to arthritis pathologies.	27387445
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	In OA, inflammation is mostly confined to the vicinity of synovial membrane while in AL macrophages infiltrated throughout the tissue.	27387445
Inflammation, Pathology	Altered Intercellular Communication	Nevertheless, in both pathologies, TGF-b1 expression was prominent in sites where the inflammation is occurring.	27387445
Diabetic Nephropathy, Inflammation	Altered Intercellular Communication	Serum and Plasma Levels of Vascular Endothelial Growth Factors in Relation to Quality of Glucose Control, Biomarkers of Inflammation, and Diabetic Nephropathy.	27388431
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Levels of vascular endothelial growth factors (VEGF) are regulated in a complex network of adipokines, glucose control, and low grade inflammation together with activated platelets, leucocytes, and endothelial dysfunction.	27388431
Diabetic Nephropathy, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Little is known about the interaction of systemic VEGF levels with quality of diabetes control, biomarkers of inflammation, and diabetic nephropathy.	27388431
Diabetic Nephropathy, Inflammation	Altered Intercellular Communication	Correlation analysis revealed a significant relationship between VEGF-A, HbA1c, inflammation, and diabetic nephropathy.	27388431
Diabetic Nephropathy, Inflammation	Altered Intercellular Communication	Mechanistic studies are needed to explore links to inflammation and diabetic nephropathy.	27388431
nervous system disorder, Inflammation	Altered Intercellular Communication	This indicates that recurrent episodes of inflammation in the CNS, as well as age, contribute to progressive neurological disease.	27388634
Inflammation	Altered Intercellular Communication	In contrast, dual (18)F-NaF bone PET/CT with early-phase scan demonstrated focal active inflammation at the surgical site of T11 spine.	27388912
Dermatitis	Altered Intercellular Communication	We showed that as a consequence, AP1S3-deficient cells up-regulate IL-1 signaling and overexpress IL-36a, a cytokine that is emerging as an important mediator of skin inflammation.	27388993
Inflammation, Rheumatism	Altered Intercellular Communication	Power Doppler ultrasonography (PDUS) is a useful method for detection of inflammation and vascularity in rheumatic diseases.	27390300
Inflammation, Fasciitis, Demographics Domain	Altered Intercellular Communication	In the remaining 3 patients with DM, significant fasciitis was not evident histologically, but mild proliferation of capillaries and mild inflammation were notable in the area of the fascia.	27390300
Inflammation	Altered Intercellular Communication	Persistent activation of NF-kB signaling is closely related to chronic inflammation and tumorigenesis.	27391066
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The lesion was totally resected, and final findings of a histopathologic examination revealed extensive fibrosis with subsiding inflammation within the tympanic membrane.	27391508
Nerve palsy, Compression, Brachial Plexus Neuritis, Optic Neuritis	Altered Intercellular Communication	Different hypotheses have been proposed for the pathophysiology of anterior interosseous nerve palsy: compression, fascicular constriction, or nerve inflammation (Parsonage-Turner syndrome).	27391838
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Histopathology from all prostate chips was assessed for inflammation and malignancy.	27391962
Inflammation, Acute myocardial ischemia	Altered Intercellular Communication	Increasing evidence suggests that inflammation and apoptosis are involved in the development of acute myocardial ischemia (AMI).	27393910
Inflammation, Atrophy of pancreas, Neoplasms	Altered Intercellular Communication	The association of serum pancreatic enzymes with pathological pancreatic atrophy and inflammation in areas adjacent to or distant from the tumor was also evaluated.	27394653
Inflammation, Neoplasms	Altered Intercellular Communication	Furthermore, low serum pancreatic amylase and lipase levels were associated with higher grade inflammation in areas distant from the tumor (P < 0.0001 and P = 0.001, respectively).	27394653
Inflammation	Altered Intercellular Communication	Nutrient patterns and chronic inflammation in a cohort of community dwelling middle-aged men.	27395328
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	While an animal-sourced pattern may enhance inflammation level, a plant-sourced pattern may reduce inflammation particularly in people with less healthy lifestyles and severe obstructive apnoea.	27395328
Infarction, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Compared with PBS, vasostatin-2 treatment prevented ischemic HF in MI rats, accompanied with reduction of infarct size, remodeling, fibrosis and inflammation, mainly through inhibition of Rho, Wnt and TLR-4 pathways and modulation of renin-angiotensin system.	27395818
Bone Diseases, Inflammation, HD Term Type, Endothelial dysfunction	Altered Intercellular Communication	Inflammation, endothelial dysfunction, and mineral bone disease are critical factors contributing to morbidity and mortality in hemodialysis (HD) patients.	27399127
HD Term Type, Inflammation	Altered Intercellular Communication	Intradialytic aerobic cycling exercise programs can effectively alleviate inflammation and improve nutrition, bone mineral density, and exercise tolerance in HD patients.	27399127
Sjogrens Syndrome", Parotitis, Inflammation	Altered Intercellular Communication	A 65-year-old female patient with recurrent parotitis due to Sjogren syndrome was referred to us, complaining of weekly bouts of inflammation.	27400144
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Our findings demonstrated that HA+PRP effectively diminished IFP adipocyte-promoted inflammation in articular chondrocytes, indicating that the IFP could be a potential therapeutic target for OA therapy.	27400716
Alzheimers Disease", Data types - Address	Altered Intercellular Communication	A neuro-inflammatory response is evident in Alzheimer's disease (AD), yet the precise mechanisms by which neuro-inflammation influences the progression of Alzheimer's disease (AD) remain poorly understood.	27400725
Myositis	Altered Intercellular Communication	The correlation between the SR and the pathologic grading suggests that SSE could be an important tool in not only the diagnosis of but also in measuring the degree of muscular inflammation.	27401595
Inflammation, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	The systemic inflammation biomarker, Neutrophil-to-Lymphocyte Ratio (NLR), has been reported as one of the adverse prognostic factors for hepatocellular carcinoma (HCC) patient.	27401641
Inflammation, Pelvic Pain	Altered Intercellular Communication	Adverse events, such as pelvic pain, inflammation, or de novo urgency, were not observed in any case during follow-up.	27401646
Disease	Altered Intercellular Communication	We postulate that acupuncture may reduce inflammation/swelling of the synovial membrane of the tendon sheath, which predominates when the disorder is of short duration.	27401746
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Faecal calprotectin, an established biomarker used to assess mucosal inflammation, has been shown to correlate with endoscopic activity in inflammatory bowel disease (IBD).	27402063
Pain Distress Question, Inflammation	Altered Intercellular Communication	The cause of pain in the course of calcaneal spur is inflammation of the attachment of the plantar fascia, which plays an important role in the process of walking and is seriously strained during different types of movement.	27402210
Inflammation, Primary malignant neoplasm, Lithiasis	Altered Intercellular Communication	Although ADMG is benign in nature, lithiasis, and chronic inflammation secondary to it may lead to dysplastic changes and cancer.	27403774
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Fatty degeneration	Altered Intercellular Communication	Clinical characteristics, biochemical profile, and histopathological data [steatosis, NAFLD activity score (NAS), hepatocyte ballooning, lobular inflammation, and degree of fibrosis] were obtained at each time point.	27405478
Inflammation	Altered Intercellular Communication	The changes in lobular inflammation and hepatocyte ballooning were not statistically significant on follow-up.	27405478
Inflammation	Altered Intercellular Communication	Considering patient preferences, drugs with daily or less frequent dosing that protect against bowel inflammation from gluten cross contamination would be best accepted.	27405659
Inflammation	Altered Intercellular Communication	It involves multiple mechanisms such as physiological risk factors, chronic inflammation, oxidant-antioxidant imbalance and proteolytic attack on extracellular matrix by matrix metalloproteinases (MMP).	27405842
Malignant tumor of colon, Inflammation, Adenoma, Ulcerative Colitis	Altered Intercellular Communication	The crude incidence rate of developing colon cancer in patients with UC was 2.45 (95 % CI 1.06-4.83) per 1000 PYD and in those with UC and polypoid adenomas within the extent of inflammation was 11.07 (95 % CI 3.59-25.83) per 1000 PYD.	27405991
Inflammation, Colorectal Carcinoma, Ulcerative Colitis	Altered Intercellular Communication	Adjusted hazards ratio of developing CRC on follow-up in UC patients with polypoid dysplastic adenomatous lesions within the extent of inflammation was 4.0 (95 % CI 1.3-12.4).	27405991
Inflammation, Colorectal Carcinoma, Ulcerative Colitis, Adenomatous Polyps	Altered Intercellular Communication	The risk of developing CRC is significantly higher in UC patients with polypoid adenomatous lesions, within the extent of inflammation, despite endoscopic resection.	27405991
ARCN1 gene, Inflammation	Altered Intercellular Communication	Perturbation experiments with a miR-218-5p mimic or inhibitor demonstrated a protective role of miR-218-5p in cigarette smoke-induced inflammation and COPD.	27409149
Renal Cell Carcinoma	Altered Intercellular Communication	Systemic immune-inflammation index predicts the clinical outcome in patients with metastatic renal cell cancer treated with sunitinib.	27409344
Refractory Cytopenia of Childhood, Renal Cell Carcinoma	Altered Intercellular Communication	In this retrospective analysis, we explored the prognostic and predictive value of the systemic immune-inflammation index (SII), based on lymphocyte, neutrophil, and platelet counts, at baseline and changes at week 6 during first-line sunitinib in patients with metastatic renal cell cancer (RCC).	27409344
Inflammation, Malnutrition	Altered Intercellular Communication	In conclusion, long-term moderate CR without malnutrition induces a significant and persistent inhibition of inflammation without impairing key in vivo indicators of cell-mediated immunity.	27410480
Inflammation, Overweight	Altered Intercellular Communication	Insulin resistance was increased in metabolically healthy overweight or obese participants (median HOMA-IR 2.63, 95% CI: 1.79-3.65, P<0.001) relative to normal-weight participants (median HOMA-IR 1.67, 95% CI: 1.08-2.67, P<0.001) as was sub-clinical inflammation but metabolically healthy overweight or obese individuals were not at increased risk of cardiovascular mortality compared with the metabolically healthy normal-weight individuals (hazard ratio 1.13, 95% CI: 0.34-3.72, P=0.8).	27412654
Sepsis, Inflammation, Acute inflammation	Altered Intercellular Communication	Consecutive ICU patients were allocated to: sepsis (n = 15), postoperative inflammation (n = 23) and intoxication without inflammation (n = 7) groups.	27414210
Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation, vitamin D and dendritic cell precursors in chronic kidney disease.	27414487
Inflammation, Chronic Kidney Diseases, Diabetes Mellitus	Altered Intercellular Communication	Instead, inflammation as a common phenomenon in CKD and diabetes mellitus had the main influence on the decrease in DCP.	27414487
Diabetic Nephropathy, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation plays a role in the development of diabetic nephropathy (DN) in type 2 diabetes.	27416772
Inflammation, Cirrhotic, Dysbiosis	Altered Intercellular Communication	HCV eradication does not impact gut dysbiosis or systemic inflammation in cirrhotic patients.	27417456
Inflammation, Liver Cirrhosis, Dysbiosis	Altered Intercellular Communication	To define the impact of sustained virological response (SVR) on gut dysbiosis and systemic inflammation in HCV cirrhosis patients.	27417456
Inflammation	Altered Intercellular Communication	Significant epithelial inflammation was present in 130 (16%) Cytosponge samples, 32 of which had ulcer slough.	27417524
Herpes Esophagitis, Inflammation, Esophagitis, Candida (fungus)	Altered Intercellular Communication	Candida and significant inflammation was detected in a further 22 (2.3%) cases; epithelial infiltration with >15 eosinophils/high-power field reflecting possible eosinophilic oesophagitis (EOE) in five (0.6%); and viral inclusions suggestive of herpes oesophagitis in one (0.1%).	27417524
Inflammation, Candida (fungus), Viral esophagitis	Altered Intercellular Communication	Eighteen cases with severe inflammation, six with candida and two with EOE were detected only at endoscopy, while 18 with candida and significant inflammation, 13 with ulcer slough, one probable EOE and one viral oesophagitis were identified on the Cytosponge only.	27417524
Malaria, Falciparum, Inflammation, Bacteremia	Altered Intercellular Communication	Reduced Parasite Burden in Children with Falciparum Malaria and Bacteremia Coinfections: Role of Mediators of Inflammation.	27418744
Psoriatic Juvenile Idiopathic Arthritis, Inflammatory abnormality of the eye, Psoriasis, Uveitis	Altered Intercellular Communication	Psoriasis and Psoriatic Arthritis-Related Uveitis: Different Ophthalmological Manifestations and Ocular Inflammation Features.	27419848
Inflammation, Diabetic Retinopathy	Altered Intercellular Communication	Because inflammation contributes to diabetic retinopathy, it is plausible that neutrophil extracellular trap formation actively occurs in diabetic retinopathy.	27420129
Inflammation, Cardiovascular Diseases, Atherosclerosis, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cessation of life	Altered Intercellular Communication	Introduction Cardiovascular disease (CVD) is the leading cause of death in post menopausal women, and inflammation is involved in the atherosclerosis process.	27420776
Inflammation	Altered Intercellular Communication	Conclusions sedentary lifestyle and high-carbohydrate intake were associated with low-grade chronic inflammation and cardiovascular risk in postmenopause.	27420776
Refractory anemias, Rheumatoid Arthritis, Have Autoimmune or Inflammatory Condition, Autoimmune Diseases	Altered Intercellular Communication	Since dendritic cells (DC) are involved in the development of autoimmune inflammation, researchers consider DC both as target cells for specific therapy of rheumatoid arthritis (RA) and as candidate cells for the development of cell-based methods to treat autoimmune diseases.	27421624
Inflammation, Impaired T cell function, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro.	27421726
vascular inflammations, Metabolic Diseases, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	On the basis of its role in vascular inflammation and in metabolic disorders, we hypothesised that the TNF superfamily (TNFSF) member 14 (LIGHT/TNFSF14) could be involved in the pathogenesis of type 2 diabetes mellitus.	27421726
vascular inflammations, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Our in vitro findings suggest that LIGHT may contribute to the progression of type 2 diabetes mellitus by attenuating insulin secretion in pancreatic islet cells and by contributing to vascular inflammation.	27421726
Inflammation, Cerebellar Ataxia	Altered Intercellular Communication	One month after IL-7 therapy, he developed worsening ataxia and CSF inflammation, which raised suspicion for immune reconstitution inflammatory syndrome.	27421731
Inflammation, Autoimmune Thyroid Disease Pathway, Edema	Altered Intercellular Communication	The human orbit is an environment that is vulnerable to inflammation and edema in the setting of autoimmune thyroid disease.	27423310
Inflammation, Malignant Neoplasms, Ulcer	Altered Intercellular Communication	A surgical biopsy of the ulcer showed inflammation with no evidence of malignancy.	27423333
Inflammation, Carcinogenesis, Obesity	Altered Intercellular Communication	Obesity is a known generator of chronic inflammation but has an uncertain role in ovarian carcinogenesis and survival.	27423378
Inflammation, Atherosclerosis, Sleep disturbances, Endothelial dysfunction, Hypertension, CTCAE	Altered Intercellular Communication	Numerous biological pathways linking sleep disturbances to atherosclerosis have been identified, such as insulin resistance, inflammation, hypertension, and endothelial dysfunction.	27423537
Inflammation	Altered Intercellular Communication	Idiopathic hypertrophic cranial pachymeningitis (IHCP) is an uncommon disease of unknown etiology characterized by thickening of the cerebral dura mater with possible associated inflammation.	27423594
Unknown (origin) (qualifier value), Inflammation	Altered Intercellular Communication	Hypertrophic Pachymeningitis (HP) denotes inflammation and thickening of the dura mater that can be idiopathic or secondary to a wide variety of conditions.	27423604
Refractory anemias, Inflammation, Rheumatoid Arthritis, Degenerative polyarthritis	Altered Intercellular Communication	Inhomogeneity of immune cell distribution in the synovial sublining layer was analyzed in order to improve our mechanistic understanding of synovial inflammation and explore potential refinements for histological biomarkers in rheumatoid arthritis (RA) and osteoarthritis (OA).	27424032
Inflammation, Atelectasis, Pneumonia, Acute Lung Injury, Respiratory Failure	Altered Intercellular Communication	The fact that patients without effusion, atelectasis, or pneumonia may develop respiratory failure, suggests that acute lung injury, possibly associated with systemic inflammation, may be important.	27424478
Occluded, Bacterial resistance, Inflammation	Altered Intercellular Communication	These conditions share common pathophysiologic features, including follicle occlusion, bacterial overgrowth, severe suppurative inflammation, scarring, and sinus tract formation.	27425163
Cerebrovascular accident	Altered Intercellular Communication	A previous animal study demonstrated an increased expression of the endocannabinoid receptor 1 (CB1R) in the penumbra area surrounding the ischemic core, suggesting a crucial role in inflammation/reperfusion after stroke.	27425766
Inflammation	Altered Intercellular Communication	Macrophage Migration Inhibitory Factor (MIF) is important to trigger inflammation processes.	27426952
Inflammation, anaphylaxis	Altered Intercellular Communication	This toxin and others can lead to reactions ranging from local inflammation to anaphylaxis.	27427329
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The right dura mater was thickened due to fibrosis and inflammation.	27427341
Inflammation, Traumatic injury, Atherosclerosis	Altered Intercellular Communication	The likely etiology of VAAs is uncertain, which includes atherosclerosis, trauma, and inflammation.	27427351
Inflammation, Osteochondritis Dissecans, Acute postoperative pain, Traumatic injury	Altered Intercellular Communication	No significant difference in the plasma CRP level was found between groups P and C. Parecoxib sodium decreases POCD incidence after total knee arthroplasty in elderly patients and may explain how this drug suppresses inflammation and acute postoperative pain caused by surgical trauma.	27428192
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	Both sex groups showed a mean hypertensive state and low-grade inflammation (C-reactive protein > 3 mg/L).	27428354
ARCN1 gene, Bacterial Infections	Altered Intercellular Communication	The pathogenesis of COPD is thought to involve bacterial infections and inflammations.	27428540
Inflammation, Skin Erosion	Altered Intercellular Communication	In 9 patients, the severity of wound complications such as inflammation or skin erosion decreased both in frequency and magnitude (eg, affected area).	27428564
Rheumatoid Arthritis	Altered Intercellular Communication	Reciprocal Relationship Between Sleep Macrostructure and Evening and Morning Cellular Inflammation in Rheumatoid Arthritis.	27428854
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	This study examined the reciprocal associations between sleep macrostructure and levels of cellular inflammation in rheumatoid arthritis (RA) patients and controls.	27428854
Refractory anemias, Inflammation	Altered Intercellular Communication	RA patients show evidence of sleep fragmentation, greater sleep depth, and higher levels of cellular inflammation.	27428854
Pain Distress Question, Inflammation, Hypersensitivity, Necrosis	Altered Intercellular Communication	Adverse reactions related to ethanolamine oleate (EO) include pain during injection, redness, inflammation, tissue necrosis, and allergic reaction.	27428925
Inflammation, Traumatic injury	Altered Intercellular Communication	Recent studies have demonstrated that surgical trauma leads to inflammation of the pancreatic remnant, which precedes PPDC.	27429037
Inflammation	Altered Intercellular Communication	Inflammation may be an important mediator of PPDC.	27429037
Inflammation, Erythema, Edema	Altered Intercellular Communication	Persistent inflammation was defined as the presence of edema, erythema, and discomfort for at least 28 days.	27429223
Inflammation, Ruptured simple cyst	Altered Intercellular Communication	Persistent inflammation was found in 1 spontaneous cyst rupture case (50%) and 1 surgically ruptured cyst (3.7%).	27429223
Inflammation, Dermoid Cyst, Rupture	Altered Intercellular Communication	Persistent inflammation is uncommon after surgical rupture of dermoid cysts, but likely after spontaneous rupture.	27429223
Inflammation	Altered Intercellular Communication	Chronic inflammation in the middle ear may result in functional impairment of the chorda tympani nerve, which carries taste from the anterior two-thirds of the tongue.	27430226
Inflammation, Brain Injuries, Subarachnoid Hemorrhage	Altered Intercellular Communication	The Role of Platelet Activation and Inflammation in Early Brain Injury Following Subarachnoid Hemorrhage.	27430874
Inflammation, Microthrombosis, Ischemia	Altered Intercellular Communication	Animal studies suggest that platelet activation and inflammation with subsequent microthrombosis and ischemia may be a mechanism of EBI.	27430874
ACSM3 gene, Inflammation	Altered Intercellular Communication	Platelet activation [thromboelastography maximum amplitude (MA)] and inflammation [C-reactive protein (CRP)] were measured serially over time during the first 72 h following SAH onset.	27430874
ACSM3 gene, Inflammation, Noninfiltrating Intraductal Carcinoma	Altered Intercellular Communication	Platelet activation and inflammation occur acutely after SAH and are associated with worse EBI, DCI and poor 3-month functional outcomes.	27430874
Nonulcer dyspepsia, Dysautonomia, Familial, Inflammation, physiopathological	Altered Intercellular Communication	Functional dyspepsia (FD) susceptibility might be influenced by polymorphisms of genes related to inflammation (CD14, macrophage migration inhibitory factor [MIF]), motor (GNB3), and sensory dysfunction (GNB3, TRPV1).	27430937
Inflammation	Altered Intercellular Communication	Polymorphonuclear neutrophils play a pivotal role in inflammation and atherogenesis.	27430968
Inflammation, Vascular Diseases	Altered Intercellular Communication	Human neutrophil peptides (HNPs) or alpha (a)-defensins are cysteine-rich cation polypeptides that are produced and released from activated polymorphonuclear neutrophil granules during septic inflammation and acute coronary vascular disorders.	27430968
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Mediators of inflammation, coagulation and fibrinolysis were compared by a univariate analysis.	27432091
Inflammation	Altered Intercellular Communication	The complement cascade terminates in the cell-surface assembly of membrane attack complexes (MACs), which promote inflammation by causing aberrant signal transduction.	27432952
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Interleukin-29 Enhances Synovial Inflammation and Cartilage Degradation in Osteoarthritis.	27433031
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Inflammation also contributes to the pathogenesis of osteoarthritis (OA).	27433031
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	In conclusion, IL-29 stimulates inflammation and cartilage degradation by OA FLS, indicating that this cytokine is likely involved in the pathogenesis of OA.	27433031
Arterial Stiffness, Inflammation, Damage, Coronary Artery Disease	Altered Intercellular Communication	Early Biomarkers of Renal Damage in Relation to Arterial Stiffness and Inflammation in Male Coronary Artery Disease Patients.	27433796
Arterial Stiffness, Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Our aim was to evaluate their relationships with arterial stiffness and inflammation in coronary artery disease (CAD) patients and in clinically healthy controls.	27433796
Inflammation, Inflammatory disorder	Altered Intercellular Communication	MMPs play a role in modulating inflammation and their impact in many inflammatory diseases has been investigated.	27434116
smooth muscle contraction, Inflammation, Fibrosis Assessment, Lower Urinary Tract Symptoms	Altered Intercellular Communication	Although inflammation and abnormal smooth muscle contractions are known to play key roles in the development of LUTS, tissue fibrosis may also be an important and previously unrecognized contributing factor.	27434301
Inflammation, Pain Distress Question	Altered Intercellular Communication	Although lubricin plays a role in controlling inflammation and pain as well as being a mechanical lubricant, clinical relevance of lubricin concentration in synovial fluid (SF) is unknown.	27435056
Myocarditis, CTCAE 5.0, Myocarditis	Altered Intercellular Communication	In patients with acute myocarditis, CMR markers of myocardial inflammation demonstrated a rapid and continuous decrease over several follow-up examinations.	27436306
Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Myocardial T1 and T2 relaxation times were the only parameters of active inflammation/edema that could discriminate between myocarditis patients and control subjects even at a convalescent stage of the disease.	27436306
Inflammation, Urinary Bladder, Underactive	Altered Intercellular Communication	We investigated urothelial barrier deficits, suburothelial inflammation and sensory proteins expressed in the bladder mucosa of patients with detrusor underactivity.	27436428
Inflammation, physiopathological, Urinary Bladder, Underactive	Altered Intercellular Communication	Urothelial dysfunction, increased suburothelial inflammation and altered sensory protein expressions in bladder mucosa were prominent in patients with detrusor underactivity.	27436428
Inflammation, Peripheral Arterial Diseases	Altered Intercellular Communication	Inflammation plays a pivotal role in peripheral artery disease (PAD).	27436494
Inflammation, diabetic	Altered Intercellular Communication	PTX-3 was not correlated with other markers of inflammation (IL-1, TNF-a and hsCRP) and diabetic metabolic parameters (hbA1c, C-peptide, insulin and HOMA-IR).	27436699
Inflammation	Altered Intercellular Communication	PTX-3 that increases similar to other markers of inflammation (IL-1, TNF-a) is a better inflammatory marker than hsCRP.	27436699
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Activated platelets are enlarged, and contain vasoactive and prothrombic factors that aggravate systemic inflammation and endothelial dysfunction.	27437641
Ischemia, Inflammation, Hypertrophy	Altered Intercellular Communication	After orthotopic heart transplantation (OHT), the allograft undergoes characteristic alterations in myocardial structure, including hypertrophy, increased ventricular stiffness, ischemia, and inflammation, all of which may decrease overall graft survival.	27437924
Inflammation, Diabetes Mellitus, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation may contribute to pathological associations among obesity, diabetes mellitus, and cardiovascular disease.	27438317
Airway structure	Altered Intercellular Communication	Fractional exhaled nitric oxide (FeNO) has been used as a marker for airway inflammation.	27438353
Abnormal degeneration	Altered Intercellular Communication	Using human and mouse MPs in vitro and inflammation-prone Cx3cr1(GFP/GFP) mice in vivo, we demonstrate that MP-derived IL-1b leads to severe CS degeneration.	27438413
Retinitis, methyldopa, Hyperplastic Polyp, Daytime, Retinitis Pigmentosa	Altered Intercellular Communication	Inhibiting subretinal MP accumulation or Il-1b might protect the CS and help preserve high acuity daytime vision in conditions characterized by subretinal inflammation, such as AMD and RP.	27438413
Inflammation, Fibrosis Assessment, Capsulitis	Altered Intercellular Communication	As such, TNC, FN1 and TGFb1 receptor I may also play roles in adhesive capsulitis by contributing to capsule inflammation and fibrosis.	27438566
Intraocular inflammation, Intraocular Lymphoma	Altered Intercellular Communication	Intraocular lymphoma often masquerades as intraocular inflammation, resulting in delayed or misdiagnosis with subsequent inappropriate management.	27438792
Aneurysm, Behavior, Inflammation	Altered Intercellular Communication	We used high-resolution magnetic resonance imaging (HRMRI) to investigate the aneurysm wall in an effort to identify evidence of inflammation invasion and define its relationship with aneurysm behavior.	27438805
Aneurysm, Inflammation	Altered Intercellular Communication	The aneurysm's wall enhancement and evidence of inflammation invasion were determined.	27438805
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In rats, both T1 and ADC correlated well with fibrosis and inflammation showing a difference between normal and diseased kidneys.	27439482
Interstitial inflammation	Altered Intercellular Communication	In KARs, MRI indices were not sensitive to interstitial inflammation.	27439482
Granulomatous inflammation, Pyelitis	Altered Intercellular Communication	Pseudotuberculous granulomatous pyelitis is a rarely reported entity, characterized by severe granulomatous inflammation limited predominantly to the renal pelvis.	27440812
allergic inflammation	Altered Intercellular Communication	Several changes in miRNA expression have been found as a result of the buildup phase of wasp VIT, with lower expression of some miRNAs involved in allergic inflammation and higher expression of those possibly involved in tolerance induction.	27441833
Inflammation, Obstructive Ureterocele, Hyperplasia	Altered Intercellular Communication	Histological investigations have confirmed the neointimal venous hyperplasia as a major pathological finding in stenotic lesions of AVF failure, due to local inflammation, oxidative stress and migration and proliferation of myofibroblasts, fibroblasts and endothelial cells.	27442395
Inflammation	Altered Intercellular Communication	The absence of TGFb expression in majority of our patients could suggest that inflammation and oxidative stress are developing later, after vascular access surgery.	27442395
Inflammation	Altered Intercellular Communication	Presence of dermal inflammation and melanoderma may contribute to atypical clinical appearance leading to biopsy despite their small clinical size.	27442449
Hepatic inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	In a murine model for hepatic inflammation during non-alcoholic fatty liver disease (NAFLD), increased antibody levels targeting OSE were found to be protective.	27443391
Inflammation, Liver damage, Obesity	Altered Intercellular Communication	Plasma IgM titers towards the P1 mimotope demonstrated an inverse correlation with markers for obesity, systemic inflammation, and liver damage.	27443391
vascular inflammations, Pulmonary Emphysema, Diabetes Mellitus	Altered Intercellular Communication	Leukocyte-endothelial adhesion is a critical early step in chronic vascular inflammation associated with diabetes, emphysema, and aging.	27444067
Inflammation, Temporal Arteritis	Altered Intercellular Communication	Is all inflammation within temporal artery biopsies temporal arteritis?	27445262
Inflammation, vascular inflammations	Altered Intercellular Communication	As ischemic events occur in patients with non-temporal artery--based inflammation, it has been recommended that any vascular inflammation within TABs be treated with corticosteroids.	27445262
Inflammation, Temporal Arteritis	Altered Intercellular Communication	TABs without transmural temporal arteritic damage accessioned between 2002 and 2012 were reviewed for inflammation (>15 perivascular lymphocytes) involving small blood vessels and/or temporal artery adventitia.	27445262
Sleep Apnea, Obstructive	Altered Intercellular Communication	Effect of Continuous Positive Airway Pressure on Airway Inflammation and Oxidative Stress in Patients with Obstructive Sleep Apnea.	27445526
Airway structure, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	Airway inflammation and oxidative stress may be linked in obstructive sleep apnea (OSA) patients.	27445526
Airway structure, Osage language	Altered Intercellular Communication	Our study demonstrates that CPAP therapy yields clinical benefits by reducing upper airway inflammation and oxidative stress in OSA patients.	27445526
Pain Distress Question, Damage, Inflammation	Altered Intercellular Communication	Paroxysmal pain was more severe, suggesting that neural damage might be aggravated by obesity-associated inflammation.	27445603
Chronic pain	Altered Intercellular Communication	Individuals with chronic pain had a greater risk factor composite than individuals without chronic pain controlling for covariates and after excluding inflammation-related health conditions (p < 0.001).	27445627
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	About 20% of cigarette smokers develop chronic obstructive pulmonary disease (COPD) due to smoke-induced irreversible damage and sustained inflammation of the airway epithelium.	27447246
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Type 2 diabetes patients (T2D) have a considerably higher cardiovascular risk, which is closely associated with systemic inflammation, and an accompanying pathologic coagulation system.	27447972
Inflammation, Damage	Altered Intercellular Communication	Biomarker levels indicative of inflammation and renal damage were lower in the young, although they exhibited higher BNP levels than older patients.	27448534
Inflammation	Altered Intercellular Communication	Inflammation mediated through TNF alpha and TGF beta 1 may represent an important component of an inflammatory response that partially drives the pathophysiology of HFpEF.	27448535
Exanthema, Discoloration of skin, Inflammatory disease of mucous membrane, Xerostomia, Palmar-plantar erythrodysesthesia syndrome, Photosensitivity of skin, Hypothyroidism, Alopecia, CTCAE, Erythema, Dyspepsia, Anorexia, Dry skin, Peripheral edema, Dysgeusia, CTCAE, Hypertension, CTCAE, Fatigue	Altered Intercellular Communication	The most common AEs in patients taking sunitinib were fatigue (70 %), hand-foot syndrome (62 %), skin rash (58 %), mucosal inflammation (58 %), anorexia (42 %), skin discoloration (42 %), followed by dry mouth, dysgeusia, dyspepsia, dry skin, dry mouth, hair color changes, hypothyroidism, alopecia, oral pain/stomatitis, hypertension, decreased weight, photosensitivity, peripheral edema, erythema, and others.	27448573
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Background Although the role of microparticles was recently implicated in stroke pathophysiology, the association between microparticles and inflammation is still not fully understood.	27448592
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Current description of osteoarthritis includes the involvement of synovial inflammation.	27449198
Degenerative polyarthritis, Inflammation, Tissue damage	Altered Intercellular Communication	During osteoarthritis, synovial fibroblasts exposed to anomalous mechanical forces and an inflammatory microenvironment release factors such as a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) metalloproteinases that mediate tissue damage and perpetuate inflammation.	27449198
Refractory anemias, Inflammation	Altered Intercellular Communication	The color fraction tends to be increased in wrist and MCP3 joints which indicate the increased blood flow pattern and color Doppler activity as part of inflammation in hand joints of RA.	27449351
Inflammation, Peripheral Arterial Diseases	Altered Intercellular Communication	Biochemical indices of oxidative stress and inflammation in the evaluation of peripheral artery disease.	27449545
Deficit, Inflammation, Excitation, Neurotoxicity Syndromes	Altered Intercellular Communication	Related pathophysiological processes reflected by these metabolites are energy deficit, inflammation, nervous excitation and neurotoxicity.	27450370
Autoimmune Diseases, Vasculitis, AAVS1 gene, Inflammation	Altered Intercellular Communication	The ANCA-associated vasculitides (AAV) are systemic autoimmune inflammatory disorders characterised by necrotising inflammation affecting small to medium-sized blood vessels.	27450392
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The neutrophil-to-lymphocyte ratio (neutrophil count divided by lymphocyte count) is a marker of inflammation associated with poor cancer outcomes.	27450715
Inflammation, Obesity, Coronary heart disease	Altered Intercellular Communication	The impact of inflammation on the obesity paradox in coronary heart disease.	27453423
Inflammation, Metabolic Diseases, Primary malignant neoplasm, Nerve Degeneration, Muscular Atrophy, Disease	Altered Intercellular Communication	These pathways are deregulated in human diseases, including cancer, neurodegeneration, metabolic disorders, muscle atrophy, ageing, and inflammation, reflecting the importance of mitophagy as a cellular housekeeping function.	27453450
Inflammation	Altered Intercellular Communication	The consequent progressive formation of ochronotic aggregates generate a severe condition of oxidative stress and inflammation in all the affected areas.	27454006
Inflammation, Neoplasms	Altered Intercellular Communication	Some of these findings were due to inflammation, whereas in most cases, uptake was seen in benign tumors of the brain or in the endocrine or exocrine glands.	27454592
Rheumatoid Arthritis, Inflammation, Inflammatory disorder	Altered Intercellular Communication	In autoinflammatory diseases, such as rheumatoid arthritis, characterized by inflammation and joint involvement, autoantibodies against oxidative post-translationally modified (oxPTM) collagen type I (CI) and type II (CII) were detected.	27454862
Inflammation, Congestion	Altered Intercellular Communication	Endoscopic findings ranged from normal gastric mucosa to severe inflammation, congestion, and friability.	27454942
Inflammation, Chronic disease of ear, Erosion of bone	Altered Intercellular Communication	Inflammation due to chronic ear disease can cause bony erosion of the carotid artery and Fallopian canals, making them more vulnerable during surgery.	27455393
Inflammation, Dysglycemia, ETV3 wt Allele, diabetic	Altered Intercellular Communication	Inflammation, matrix metalloproteinases and dysglycemia markers are not expressed in isolation but rather concurrently and are continuously interacting with each other, in MetS and diabetics patients.	27455450
Inflammation, Arthritis, Psoriatic	Altered Intercellular Communication	These findings have important implications for understanding the role of MHC alleles in directing the adaptive immune response to mediate the inflammation responsible for psoriatic arthritis.	27455857
Granulomatous inflammation	Altered Intercellular Communication	Two skin biopsies and a biopsy of the olecranon bursa revealed granulomatous inflammation.	27456320
Diabetes Mellitus, Insulin-Dependent, Inflammation, IGHD1-7 gene	Altered Intercellular Communication	Patients with type 1 diabetes (DM1) have distinct gut microbiota in comparison to non-diabetic individuals, and it has been linked to changes in intestinal permeability, inflammation and insulin resistance.	27456494
Inflammation, IGHD1-7 gene	Altered Intercellular Communication	Prebiotics are a potentially novel, inexpensive, low-risk treatment addition for DM1 that may improve glycemic control by changes in gut microbiota, gut permeability and inflammation.	27456494
Inflammation, Heat-Shock Proteins 70, Chronic sinusitis	Altered Intercellular Communication	HSP70 is associated with the severity of inflammation in chronic rhinosinusitis.	27456583
Airway structure	Altered Intercellular Communication	Nasal secretions include cytokines and inflammatory mediators that are involved in the pathogenesis of upper airway inflammation.	27456583
Inflammation, Myelosuppression	Altered Intercellular Communication	The observed myelosuppression was not driven by inflammation and thus other mechanisms are at play.	27456951
Acute inflammation, Neoplasms	Altered Intercellular Communication	Restaging computed tomography at the time of referral showed findings in the hepatoduodenal ligament and gallbladder fossa concerning residual tumor versus postoperative inflammation.	27456958
Inflammation, Venous Thrombosis	Altered Intercellular Communication	In BD, the inflammation on vessel walls causes venous thrombosis.	27457028
Inflammation, Primary malignant neoplasm, Cardiovascular Diseases, Infection, Cerebrovascular accident	Altered Intercellular Communication	A leading hypothesis proposes that increased human life span since 1850 has resulted from decreased exposure to childhood infections, which has reduced chronic inflammation and later-life mortality rates, particularly from cardiovascular disease, stroke, and cancer.	27457937
Communicable Diseases, Inflammation	Altered Intercellular Communication	Our results do not support the prevailing assertion that exposure to infectious diseases in early life has long-lasting associations with later-life all-cause mortality risk or mortality putatively linked to chronic inflammation.	27457937
Lower Urinary Tract Symptoms, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	The prevalence of prostatic inflammation (PI) is very frequent in patients affected by benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS).	27458062
Non-alcoholic Fatty Liver Disease, ETV3 wt Allele, prostatitis	Altered Intercellular Communication	To investigate the relationship between prostatic inflammation (PI) and the presence of MetS and non-alcoholic fatty liver disease (NAFLD) in a cohort of patients affected by BPH/LUTS.	27458062
Inflammation, Non-alcoholic Fatty Liver Disease, ETV3 wt Allele	Altered Intercellular Communication	The coexistence of MetS and NAFLD exerted a greater detrimental effect on prostate gland by increasing severity of inflammation.	27458062
Inflammation	Altered Intercellular Communication	Adipose tissue (AT) inflammation leads to increased free fatty acid (FFA) efflux and ectopic fat deposition, but whether AT dysfunction drives selective fat accumulation in specific sites remains unknown.	27458255
Orchitis	Altered Intercellular Communication	Most cases of diverticular inflammation are mild and require only medical treatment with liquid diet and antibiotics.	27458848
Plaque, Atherosclerotic	Altered Intercellular Communication	Similar Impact of Clopidogrel or Ticagrelor on Carotid Atherosclerotic Plaque Inflammation.	27459273
Plaque, Atherosclerotic	Altered Intercellular Communication	Inhibitors of the P2Y12 receptor, which is involved in platelet activation, may have a direct effect on carotid atherosclerotic plaque inflammation.	27459273
Inflammation	Altered Intercellular Communication	The initiation and progression of GC are associated with inappropriate immune responses caused by chronic inflammation of the gastric mucosa.	27459504
Inflammation, Immune System Diseases	Altered Intercellular Communication	Impaired Zn status promotes immune dysfunction, and it has been associated with enhanced chronic inflammation during aging.	27459881
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Though the pathophysiological mechanisms are not exactly known, increased inflammation and platelet reactivity could play an important role in the occurrence of stroke during AMI.	27459905
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Moreover, these results provide new insights into the potential role played by increased inflammation and platelet reactivity in the occurrence of stroke after AMI.	27459905
Coronary heart disease	Altered Intercellular Communication	Association of six CpG-SNPs in the inflammation-related genes with coronary heart disease.	27461004
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Chronic inflammation has been widely considered to be the major risk factor of coronary heart disease (CHD).	27461004
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	In conclusion, all the six inflammation-related CpG-SNPs (rs16944, rs2071008, rs12732361, rs2065666, rs9395208, and rs1800686) were associated with CHD in the combined or subgroup tests, suggesting an important role of inflammation in the risk of CHD.	27461004
Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	It is characterized by a slow onset and invasive organisms with non-granulomatous inflammation seen on histopathology.	27463614
Inflammation, Benign prostatic hypertrophy, Metabolic Syndrome X	Altered Intercellular Communication	Association between Benign Prostatic Hyperplasia and Neutrophil-Lymphocyte Ratio, an Indicator of Inflammation and Metabolic Syndrome.	27464069
Inflammation, Lower Urinary Tract Symptoms, ETV3 wt Allele	Altered Intercellular Communication	Here, we aimed at evaluating the role of neutrophil-lymphocyte ratio (NLR), an indicator of inflammation and MetS, in the pathogenesis of LUTS and other BPH-related parameters.	27464069
Inflammation, fibrogenesis	Altered Intercellular Communication	Galectin-3 (Gal-3), a novel biomarker involved in inflammation, tissue repair and fibrogenesis, might be a valuable predictor of LVR.	27465055
Inflammation	Altered Intercellular Communication	Patients who have undergone allogeneic stem cell transplantation represent a unique population that may offer novel insight into the pathways involved in radiation-related inflammation.	27465468
Inflammation, Weight decreased, Hypertension, CTCAE	Altered Intercellular Communication	Heightened surveillance for risk, and adoption of healthy living recommendations specifically directed toward weight reduction, hypertension management, and inflammation control, should be incorporated as a priority for disease prevention and management.	27465752
Crohn Disease, Fibrosis Assessment, Inflammation, Granuloma	Altered Intercellular Communication	The Lennard-Jones criteria are considered the gold standard for diagnosing Crohn's disease (CD) and include the items granuloma, macroscopic discontinuity, transmural inflammation, fibrosis, lymphoid aggregates and discontinuous inflammation on histology.	27466047
Granuloma, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	A new index was derived from granuloma, fibrosis, transmural inflammation and macroscopic discontinuity, but excluded lymphoid aggregates and discontinuous inflammation on histology.	27466047
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Serum LRG is a novel biomarker for detecting MH during disease course in patients with UC and a surrogate marker of endoscopic inflammation in patients with normal CRP levels.	27466171
Inflammation, Fibrosis Assessment, Albuminuria, Glomerulosclerosis (disorder)	Altered Intercellular Communication	Instead, accumulation of lipid-containing lamellar bodies in renal tubuli was detected in P4h-tm-/- mice with aging, resulting in inflammation and fibrosis, and later glomerular sclerosis and albuminuria.	27466183
Inflammation, Breast Carcinoma, Cancer Pain	Altered Intercellular Communication	Poor breast cancer-related quality of life is associated with flattened cortisol rhythms and inflammation in breast cancer survivors and women with advanced disease.	27466289
Inflammation	Altered Intercellular Communication	Co-existing biliary inflammation was detected in 8 patients.	27466492
Inflammation, Lobe of liver, Type 1 Autoimmune Pancreatitis, Sclerosis, Damage, Cholestasis	Altered Intercellular Communication	Immunoglobulin G4-hepatopathy, which includes various histopathological lesions encountered in the liver of patients with type I autoimmune pancreatitis, is classified into five histological categories: portal inflammation, large bile duct damage, portal sclerosis, lobular hepatitis, and cholestasis.	27466793
Inflammation, Diabetes Mellitus, Insulin-Dependent, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8	Altered Intercellular Communication	Several studies have evaluated the role of inflammation in type 1 diabetes (T1D).	27467009
Inflammation, Blood coagulation	Altered Intercellular Communication	This is a significant polypeptide released in pretty much all cells and important for the regulation of cellular events, epithelium formation, inflammation, blood coagulation, and collagen synthesis.	27467498
Inflammation, Dental Plaque, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	ACS is associated with a pan-inflammatory state, and intraplaque features of inflammation correlate with coronary plaque progression.	27468140
Inflammation	Altered Intercellular Communication	After platelet transfusion, we observed a transient and slight increase in inflammation parameters.	27468945
Gingivitis	Altered Intercellular Communication	Longitudinal analysis of 6,316 Kuwaiti children revealed that shorter sleep duration and higher salivary glucose levels were both associated with increased gingival inflammation.	27470068
Inflammation, Depressed mood	Altered Intercellular Communication	This study suggests that stressful events in childhood are associated with shorter TL in middle-aged men and that part of this relation is explained by depressive mood and low grade inflammation.	27470228
Inflammation, Osteochondritis Dissecans	Altered Intercellular Communication	The pathophysiology of POCD remains elusive, but previous work showed that intravenous lidocaine may be protective against POCD, possibly by modulating cerebral inflammation.	27470233
Inflammation	Altered Intercellular Communication	This may be a manifestation of reduced cerebral inflammation during cardiopulmonary bypass in response to treatment with lidocaine.	27470233
Myopia, Inflammation	Altered Intercellular Communication	Role of Chronic Inflammation in Myopia Progression: Clinical Evidence and Experimental Validation.	27470424
Inflammation, Memory for Designs Test	Altered Intercellular Communication	We found atropine downregulated inflammation in MFD eyes.	27470424
Myopia, Inflammation	Altered Intercellular Communication	These findings provide clinical and experimental evidence that inflammation plays a crucial role in the development of myopia.	27470424
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	It is increasingly becoming accepted that inflammation may play an important role in the pathogenesis of Alzheimer's disease (AD), as several immune-related genes have been associated with AD.	27470609
Aortic Aneurysm, Aortitis	Altered Intercellular Communication	BACKGROUND Inflammation of the aortic wall, known as aortitis, is a rare clinical entity which is frequently asymptomatic, or identified when the patient presents with an aortic aneurysm or dissection.	27471062
Inflammation, Fibrosis Assessment, Lung Diseases, Interstitial, Lung Injury	Altered Intercellular Communication	Evidence suggests that lung injury, inflammation and extracellular matrix remodelling precede lung fibrosis in interstitial lung disease (ILD).	27471206
Liver carcinoma, FAM126A gene	Altered Intercellular Communication	Various inflammation-based prognostic scores have been associated with poor survival in patients with hepatocellular carcinoma (HCC), and neutrophils display important roles.	27472390
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic Syndrome X, Atherosclerosis	Altered Intercellular Communication	Since changes in some immune system indicators such as leukocyte count and neutrophil to lymphocyte ratio in the blood and Inflammation is directly in relation with the pathogenesis of type 2 diabetes, metabolic syndrome and atherosclerosis, measuring these indicators in patients with type 2 diabetes and comparing them with control group can be a suitable indicator of Inflammation and prognosis of the disease.	27472870
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Considering the findings of current study, we showed the inflammation and the pathogenesis caused by type 2 diabetes can be attributed to neutrophil to lymphocyte ratio.	27472870
Degenerative polyarthritis, Inflammation, Musculoskeletal Diseases	Altered Intercellular Communication	Osteoarthritis (OA) is a chronic systemic musculoskeletal disorder involving inflammation, immunity, and metabolic alterations.	27472907
Degenerative polyarthritis, Inflammation, Inflammatory disorder	Altered Intercellular Communication	OA is commonly regarded as non-inflammatory disease; still inflammation is recognized as contributing to the symptoms and progression of OA.	27472907
Pneumonitis	Altered Intercellular Communication	Low tidal volume ventilation with low PEEP during surgery may induce lung inflammation.	27473050
Pneumonitis	Altered Intercellular Communication	Low tidal-volume ventilation with low positive end-expiratory pressure may lead to pulmonary inflammation during major surgery such as hepatectomy.	27473050
Inflammation, Bacterial Infections	Altered Intercellular Communication	Its homeostasis is tightly linked to oxidative stress, bacterial infections and systemic inflammation.	27473364
Single organ dysfunction, Inflammation, Alcoholic Intoxication, Chronic	Altered Intercellular Communication	Transferrin, TSAT and ferritin differentially correlated with the severity of organ failure, active alcoholism and surrogates of systemic inflammation and macrophage activation.	27473364
Single organ dysfunction, Inflammation	Altered Intercellular Communication	Lower transferrin (continuous or dichotomized at 87 mg/dL) and consecutively higher TSAT (continuous or dichotomized >41%) indicated increased mortality within 30 days and remained significant after adjustment for organ failure and inflammation in multivariate regression models and across subgroups of patients.	27473364
Excessive tearing, Inflammation	Altered Intercellular Communication	Clinical symptoms of epiphora settled with topical steroid drops, but the clinical signs of chronic tarsal inflammation persisted until withdrawal of the facial wipes thought to contain the inciting agent, though the exact nature of this remains unclear.	27473439
Cardiovascular morbidity, Psoriasis	Altered Intercellular Communication	Inflammation of systemic and vascular tissues besides the skin in psoriasis is associated with cardiovascular morbidity and mortality.	27473449
Inflammation, neuron death, Cerebrovascular accident	Altered Intercellular Communication	Ischemic stroke (IS) usually initiates inflammation and oxidative stress leading to neuronal death.	27474112
Inflammation, diabetic	Altered Intercellular Communication	Finally, fasting glucose and HbA1c may also be useful indicators for cerebrovascular risk in diabetic patients that may be mediated by low levels of antioxidative defense markers and high inflammation status.	27474112
Inflammation, Atherosclerotic renal artery stenosis, renal hypoxia	Altered Intercellular Communication	Atherosclerotic renal artery stenosis (ARAS) reduces renal blood flow (RBF), ultimately leading to kidney hypoxia and inflammation.	27474749
Perihilar Cholangiocarcinoma	Altered Intercellular Communication	Appraisal of inflammation-based prognostic scores in patients with unresectable perihilar cholangiocarcinoma.	27474781
Primary malignant neoplasm	Altered Intercellular Communication	Inflammation-based prognostic scores are useful prognostic indicators for several types of cancer.	27474781
Inflammation, Neoplasms	Altered Intercellular Communication	Tumor size greater than 2 mm and inflammation were risks for false-positives.	27475968
Autoimmune Diseases, Vasculitis, AAVS1 gene, Inflammation	Altered Intercellular Communication	Anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitides (AAV) are a group of systemic autoimmune disorders characterized by necrotizing inflammation of small- to medium-sized blood vessels.	27476166
Inflammation, Osteoporosis, Postmenopausal	Altered Intercellular Communication	Serum FKN concentrations were negatively associated with BMD at femoral neck (r = -0.394, p = 0.004), total hip(r = -0.374, p = 0.006), internal trochanter(r = -0.340, p = 0.013), greater trochanter(r = -0.376, p = 0.006), Ward's triangle(r = -0.343, p = 0.012), L1-L4 lumbar spine(r = -0.339, p = 0.013) and positively associated with VAS (r = 0.321, p = 0.019) and ODI (r = 0.377, p = 0.005) scores, bone turnover makers (TRACP-5b:r = 0.341, p = 0.012; NTX:r = 0.364, p = 0.007)as well as inflammation markers (IL-1b: r = 0.396, p = 0.003; IL-6:r = 0.355, p = 0.009) in postmenopausal osteoporotic patients.	27476376
Fear (Mental Process), Inflammation, Alopecia, CTCAE, Peeling of skin	Altered Intercellular Communication	Dermatological examination of the capillitium found a zone of incomplete alopecia in the frontoparietal and parietotemporal area, without inflammation, desquamation, and scaring.	27477178
Inflammation	Altered Intercellular Communication	On histologic examination, there are typically increased numbers of catagen and telogen hairs without evidence of inflammation.	27477178
Airway structure, mucus secretion	Altered Intercellular Communication	Cold-inducible RNA-binding protein mediates airway inflammation and mucus hypersecretion through a post-transcriptional regulatory mechanism under cold stress.	27477308
ARCN1 gene, Airway structure	Altered Intercellular Communication	In this study, we showed that CIRP gene and protein levels were significantly increased in patients with COPD and in rats with chronic airway inflammation compared with healthy subjects.	27477308
Fever, Acute inflammation, Neoplasms, Back Pain	Altered Intercellular Communication	A 63-year-old man with a jugular tumor in the skull base was referred to our hospital for an evaluation of pyrexia, back pain, and acute inflammation.	27477424
Steatohepatitis, Non-alcoholic Fatty Liver Disease, Inflammation	Altered Intercellular Communication	The complement component C5 promotes liver steatosis and inflammation in murine non-alcoholic liver disease model.	27477770
Inflammation, Adrenoleukodystrophy	Altered Intercellular Communication	Considering that component C5 is a central mediator of inflammation, we investigated the role of C5 in the establishment of NALD.	27477770
Fatty degeneration	Altered Intercellular Communication	Again, B6 C5(+) HFDG-fed mice developed more steatosis, liver centro-lobular inflammation and presented higher levels of liver IL-1b, IL-12p70, IL-17 and TFG-b than B6 C5(-) mice under the same conditions.	27477770
Steatohepatitis, Inflammation, Adrenoleukodystrophy	Altered Intercellular Communication	We concluded that murine C5 contributes effectively to liver steatosis and inflammation in NALD pathogenesis.	27477770
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Increased inflammation and disease activity among current cigarette smokers with rheumatoid arthritis: a cross-sectional analysis of US veterans.	27477806
Maxillary Sinusitis, Inflammatory abnormality of the eye, Ethmoid Sinusitis	Altered Intercellular Communication	Thirty-nine (17.8%) of 218 patients showed either maxillary sinusitis or ethmoidal sinusitis and 32 (14.7%) of 218 patients presented with periocular inflammation.	27478350
Intraocular inflammation	Altered Intercellular Communication	The records of consecutive patients with intraocular inflammation of unknown etiology were reviewed.	27478352
Intraocular inflammation	Altered Intercellular Communication	OT is a common cause of intraocular inflammation in the tertiary hospital setting.	27478352
Inflammation, Overweight	Altered Intercellular Communication	The Presence and Duration of Overweight Are Associated with Low-Grade Inflammation in Prepubertal Chilean Children.	27478998
Inflammation, Overweight	Altered Intercellular Communication	Overweight is associated with low-grade inflammation, but it is under debate whether the effect of fat mass accumulation is acute or chronic.	27478998
Necrotizing granulomatous inflammation, Carcinoma, Thoracic lymphadenopathy	Altered Intercellular Communication	The Intranodal Presence of Coexisting Granulomatous Inflammation and Carcinoma During Transbronchial Needle Aspiration of Intrathoracic Lymphadenopathy.	27479015
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The presence of nodal granulomatous inflammation in patients with underlying malignancy is well reported.	27479015
Granulomatous inflammation, Malignant Neoplasms	Altered Intercellular Communication	However, review of 3 recent large trials of endobronchial ultrasound-guided transbronchial needle aspiration in patients with granulomatous inflammation and malignancy did not identify the presence of coexisting, intranodal malignancy, and granulomatous inflammation, rather these diagnoses remained nodally exclusive.	27479015
Inflammation, Carcinoma	Altered Intercellular Communication	We present a case of coexisting granulomatous inflammation and metastatic carcinoma within the same lymph node aspirates, reviewing the potential diagnostic pitfalls and implications of this rare occurrence.	27479015
Communicable Diseases, Inflammation, Disease	Altered Intercellular Communication	When it is carried out in cases of stone disease, however, it is frequently not a "simple" technique owing to the presence of significant inflammation and infection.	27479686
Inflammation	Altered Intercellular Communication	In young patients, the authors observed multiple, small calcified bodies within the dermis surrounded by chronic inflammation and granulomatous foreign body reaction.	27479867
Fibrous, Chronic inflammation	Altered Intercellular Communication	On the other hand, in elderly patients, lesions were characterized by a single, large, well-demarcated amorphous calcified deposit surrounded by fibrous tissue, without chronic inflammation or foreign body reaction.	27479867
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	We aimed to characterize endoplasmic reticulum stress, inflammation, and Alzheimer's disease (AD) related markers in peripheral blood mononuclear cells (PBMCs) from males with varied BMI; and to explore whether high glucose and fatty acids (FFAs) might be critical factors for inducing metabolic alterations in PBMCs under obese condition.	27481183
Sepsis, Inflammation, Lymphohistiocytosis, Hemophagocytic	Altered Intercellular Communication	Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition characterized by uncontrolled inflammation and has common clinical and laboratory features with sepsis.	27481757
Inflammation, Autonomic nervous system disorders, Diabetes Mellitus	Altered Intercellular Communication	Associations between cardiovascular autonomic dysfunction and subclinical inflammation, both risk factors of diabetic comorbidities and mortality, have been proposed in non-diabetic populations, while data for type 1 and type 2 diabetes are conflicting.	27481890
Autonomic nervous system disorders, Diabetes Mellitus	Altered Intercellular Communication	Our aim was to investigate associations between inflammation-related biomarkers and cardiac autonomic dysfunction in patients with diabetes.	27481890
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Autonomic nervous system disorders, Diabetes Mellitus	Altered Intercellular Communication	We characterised the associations between seven biomarkers of subclinical inflammation and cardiac autonomic dysfunction based on heart rate variability and cardiovascular autonomic reflex tests (CARTs) in 161 individuals with type 1 and 352 individuals with type 2 diabetes (time since diagnosis of diabetes <1 year).	27481890
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Autonomic nervous system disorders	Altered Intercellular Communication	Biomarkers of inflammation were differentially associated with diminished cardiac autonomic dysfunction in recent-onset type 2 diabetes.	27481890
Myocardial fibrosis, vascular inflammations	Altered Intercellular Communication	In addition, patients in the omega-3 fatty acid arm underwent significant reductions in serum biomarkers of systemic and vascular inflammation and myocardial fibrosis.	27482002
Inflammation, Fibrosis Assessment, Ventricular Remodeling, Acute myocardial infarction, Infarction	Altered Intercellular Communication	Treatment of patients with acute myocardial infarction with high-dose omega-3 fatty acids was associated with reduction of adverse left ventricular remodeling, noninfarct myocardial fibrosis, and serum biomarkers of systemic inflammation beyond current guideline-based standard of care.	27482002
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The role of diet-associated inflammation in colorectal cancer is of interest.	27483316
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Results from this study suggest that diet-associated inflammation may increase the risk of colorectal cancer, and this effect may differ by certain factors, such as anatomical site, age, sex, and lifestyle.	27483316
Suicidal behavior, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Emerging evidence suggests that inflammation has a key role in depression and suicidal behavior.	27483383
Gingivitis	Altered Intercellular Communication	Most of the participants presented with gingival inflammation, which was less in 12-year-old females.	27484595
Refractory anemias, Rheumatoid Arthritis, Periodontitis	Altered Intercellular Communication	Rheumatoid arthritis (RA) and periodontitis are common chronic inflammatory conditions.	27484603
hormone deficiency, Immune System Diseases	Altered Intercellular Communication	Growth hormone is important for the development and function of the immune system, but there is controversy on whether growth hormone deficiency is associated to immune disorders.	27484773
Inflammation	Altered Intercellular Communication	Chronic inflammation has been associated with the development of MM in rare instances and these three cases suggest that CD with transmural inflammation may also be a precursor.	27484913
Inflammation, Carcinogenesis	Altered Intercellular Communication	The precise role of CD-related transmural inflammation in the carcinogenesis of peritoneal MM remains to be determined.	27484913
Synovitis, Inflammation, Rheumatoid Factor, Tenosynovitis	Altered Intercellular Communication	We performed cross-sectional analysis of the association of ACPA, rheumatoid factor (RF) and anti-carbamylated protein (anti-CarP) antibodies with BME and other types of inflammation (synovitis, tenosynovitis) detected by magnetic resonance imaging (MRI).	27485323
Barrett Esophagus	Altered Intercellular Communication	Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma.	27486097
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Local and systemic inflammation is considered an important contributor to OA pathogenesis.	27486097
ARCN1 gene, Pulmonary Emphysema, Pneumonitis, Exacerbation	Altered Intercellular Communication	Azithromycin (AZM) reduces pulmonary inflammation and exacerbations in patients with COPD having emphysema.	27486204
Inflammation	Altered Intercellular Communication	These data suggest that the activation of the innate immune system and inflammation via TLR activation might have an essential role in the pathogenesis of PTDM in renal transplantation.	27486667
Pain Distress Question, Inflammation, Obesity	Altered Intercellular Communication	We examined whether the obesity and pain relationship is mediated by the high-sensitivity C-reactive protein (hsCRP), a nonspecific marker of systemic inflammation, and whether this relationship differs by sex.	27486843
Neoplasms, Primary malignant neoplasm, Obesity, prostatitis	Altered Intercellular Communication	The aim of this pilot study was to examine prostatic inflammation via tumor infiltrating lymphocytes and macrophages characterized by obesity and cancer severity.	27487262
Inflammation, Prostate carcinoma	Altered Intercellular Communication	However, these inflammation markers were associated with poor prostate cancer outcomes.	27487262
Inflammation, Atherosclerosis	Altered Intercellular Communication	In addition, the relationship between CRP, atherosclerosis, and inflammation remains controversial.	27487299
Inflammation, Lymphoid hyperplasia, Appendicitis, CTCAE	Altered Intercellular Communication	Acute inflammation was seen in 69 (48.9%) patients, lymphoid hyperplasia in 39 (27.7%) patients while parasitic appendicitis was seen in one (0.7%) patient.	27487611
Vascular Diseases, Inflammation, Fibrosis Assessment, Blood Clot, Hyperplasia	Altered Intercellular Communication	On the basis of a systematic clinicopathologic review of these 11 cases identified between 1982 and 2014, we describe a distinct mesenteric vasculopathy that involves both arteries and veins [mesenteric arteriovenous dysplasia/vasculopathy (MAVD/V)] and is characterized by (1) concentric/eccentric smooth muscle collarette around the tunica media of both the artery and the vein in >=2 foci, (2) varying degrees of intimal and medial hyperplasia and adventitial fibrosis, and (3) lack of inflammation or thrombi.	27487739
Chronic purulent otitis media, Otitis Media, Ear discharge	Altered Intercellular Communication	Chronic suppurative otitis media (CSOM) presents with purulent otorrhea (ear discharge), is characterized by chronic inflammation of the middle ear and mastoid cavity, and contributes to a significant disease burden worldwide.	27487953
Inflammation, Thrombosis, Disseminated Intravascular Coagulation, SLC25A10 gene	Altered Intercellular Communication	Neutrophils extracellular traps (NETs) have recently emerged as a new potential link between inflammation, immunity, and thrombosis and could play a key role in septic shock-induced disseminated intravascular coagulation (DIC) pathogenesis.	27488091
Inflammation, Tuberculosis	Altered Intercellular Communication	The commonest diagnosis seen was granulomatous inflammation consistent with tuberculosis (33.3%).	27489015
Rheumatoid Arthritis, Autonomic neuropathy, Chronic inflammation	Altered Intercellular Communication	Rheumatoid arthritis can cause cardiac autonomic neuropathy from chronic inflammation.	27489064
Degenerative polyarthritis, Inflammation, Degenerative disorder of cartilage	Altered Intercellular Communication	In particular, chronic inflammation may contribute to stress-induced senescence of chondrocytes and cartilage degeneration during OA progression.	27490266
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, atherosclerotic	Altered Intercellular Communication	Matrix metalloproteinases -2 and -9 (MMP-2 and MMP-9), which degrade collagen type IV of the vascular basement membrane, are responsible for vascular remodeling, inflammation, and atherosclerotic complications, including in type 2 diabetes (T2D).	27490532
Inflammation	Altered Intercellular Communication	However, the interaction between interviewer-rated acute stress and chronic family stress was significantly associated with adolescent inflammation markers (IL-6, IL-1ra).	27490853
Inflammation, selenium	Altered Intercellular Communication	Specifically, as chronic family stress increased, the association between acute stressor impact (interviewer-rated) and inflammation markers became more positive (IL-6 (B = .054, SE = .023, p = .022); IL-1ra (B = .030, SE = .014, p = .034)).	27490853
Inflammation	Altered Intercellular Communication	Among adolescents, interviewer-based ratings of acute stressor impact may allow for better prediction of health-relevant inflammation markers than adolescents' own ratings.	27490853
Inflammation	Altered Intercellular Communication	Subclinical inflammation is associated with development of increased glycaemia, insulin resistance and beta-cell function in non-diabetic individuals.	27491375
Inflammation, Hyperplasia	Altered Intercellular Communication	Mimickers of well-differentiated PC on mpMRI were inflammation, adenosis, HG-PIN and post-atrophic hyperplasia.	27491874
Sepsis, Communicable Diseases, Inflammation	Altered Intercellular Communication	The pathogen also needs to be considered in the challenging case of doubtful infection, where perhaps the only sign is inflammation, for a more accurate prediction of progression to either sepsis or healing.	27492065
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation.	27492330
Inflammation	Altered Intercellular Communication	Increased pulmonary vascular permeability and inflammation due to Ang-2 may play a role in the pathogenesis of AE-IIPs.	27492510
Inflammation, Heart failure	Altered Intercellular Communication	The chronic inflammation plays an important role in heart failure and complement components might be useful markers of the prognosis.	27492980
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Emotion Dysregulation and Inflammation in African-American Women with Type 2 Diabetes.	27493807
Minimal Disseminated Disease, Inflammation, Post-Traumatic Stress Disorder, Unipolar Depression	Altered Intercellular Communication	C-reactive protein (CRP), a marker of systemic inflammation, has been associated with major depressive disorder (MDD) and posttraumatic stress disorder (PTSD).	27493807
Inflammation, Immune dysregulation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The objective of this study was to determine whether inflammation is associated with emotion dysregulation in women with type 2 diabetes mellitus (T2DM).	27493807
Inflammation	Altered Intercellular Communication	These findings suggest that emotion dysregulation may be an important risk factor for chronic inflammation beyond already known risk factors among women with T2DM, though a causal relationship cannot be determined from this study.	27493807
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Stress and inflammation are both important risk factors for coronary artery disease (CAD).	27494070
Inflammation, cervical cancer, cervical abnormality, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	These samples contained cervical abnormalities enriched with inflammation (n = 107), cervical intraepithelial neoplasia (CIN) I (n = 19), CINII-III (n = 9) and cervical cancer (n = 31).	27494179
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Fucosylation is an important oligosaccharide modification associated with cancer and inflammation.	27494861
Inflammation, Cancer of Digestive System	Altered Intercellular Communication	The association between biliary tract inflammation and risk of digestive system cancers: A population-based cohort study.	27495065
Inflammation, Cancer of Digestive System	Altered Intercellular Communication	The relationship between biliary tract inflammation (BTI) and digestive system cancers is unclear.	27495065
Cholecystitis, Malignant neoplasm of stomach	Altered Intercellular Communication	The aHR of stomach cancer was also found to be increased (2.73; 95% CI: 1.28-5.81) in patients with gallbladder inflammation only.	27495065
Refractory anemias, Rheumatoid Arthritis, Damage	Altered Intercellular Communication	It is recognized that CC chemokine receptor 3 (CCR3) is associated with numerous inflammatory conditions and fibroblast-like synoviocyte (FLS) invasiveness correlates with articular damage in rheumatoid arthritis (RA).	27495116
Sepsis, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Diabetes is associated with chronic inflammation and activation of the vascular endothelium and the coagulation system, which in a more acute manner are also observed in sepsis.	27495247
Sepsis, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Plasma biomarker measurements revealed signs of systemic inflammation, and strong endothelial and coagulation activation in patients with sepsis, none of which were altered in those with diabetes.	27495247
Lupus Erythematosus	Altered Intercellular Communication	Chronic inflammatory conditions such as systemic lupus erythematosus considered as a recognize cause.	27495304
Mediastinitis	Altered Intercellular Communication	MIE was completed laparoscopically in 93 % of patients; two patients required conversion to an open procedure due to mediastinal inflammation following neoadjuvant chemoradiation.	27495339
Inflammation, Atherosclerosis	Altered Intercellular Communication	Increasing evidence points to the inflammatory character of atherosclerosis and several parameters of inflammation have been proposed as cerebrovascular risk markers.	27498442
Inflammation, Obstruction	Altered Intercellular Communication	Inflammation and obstruction of channel of sweat glands used to be thought to be the basis of this disease.	27498534
Dermatitis, Atopic, Inflammation	Altered Intercellular Communication	The patient was treated with Dr Michaels(r) (Eczitinex(r) and Itchinex(r)) ointment and herbal supplements and presented total resolution of the atopic eczema and underlying inflammation within 6 weeks.	27498656
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Dietary factors and inflammation markers have been shown to play a role in the development of depression.	27498949
APP gene, Inflammation	Altered Intercellular Communication	It has been reported that development of AAA is associated with inflammation of the vascular wall; however, the mechanism of AAA rupture is not fully understood.	27499372
Inflammation	Altered Intercellular Communication	In the acute setting there is inflammation and an additional protein deficiency.	27499393
Communicable Diseases, Pneumonitis	Altered Intercellular Communication	Matrix metalloproteinases-9 (MMP-9) is considered significant in the pathogenesis of lung inflammation and infection.	27499696
Neoplasms, Ulcerative Colitis, Colitis	Altered Intercellular Communication	Effect of appendicectomy on colonic inflammation and neoplasia in experimental ulcerative colitis.	27500367
Inflammation, Lesion of liver, Necrosis, Fibrosis Assessment, Hepatotoxicity	Altered Intercellular Communication	Histopathological liver lesions were different depending on the onset of hepatotoxicity (acute or subacute): acinar zone 3 necrosis in case of acute symptoms, and portal tract inflammation with porto-central bridging and fibrosis in the delayed presentation.	27500989
Inflammation, physiopathological	Altered Intercellular Communication	The key metabolites and pathways may be possibly correlated with smooth muscle tone changes, increased collagen content, and inflammation, which have been identified as potential contributors to urinary dysfunction in humans and rodents.	27502322
Inflammation	Altered Intercellular Communication	IL-22 is an IL-10-family cytokine that regulates chronic inflammation.	27502468
Inflammation, Endothelial dysfunction, atherosclerotic	Altered Intercellular Communication	Here, we showed that adeno-associated viruses-GDF11 and recombinant GDF11 protein improve endothelial dysfunction, decrease endothelial apoptosis, and reduce inflammation, consequently decrease atherosclerotic plaques area in apolipoprotein E-/- mice.	27502608
Gastrointestinal Hemorrhage, Obstruction, Inflammation	Altered Intercellular Communication	Most often is asymptomatic but it may give a number of complications including gastrointestinal bleeding, obstruction and inflammation.	27502885
Refractory anemias, Inflammation, Lymphoma	Altered Intercellular Communication	However, since the excess risk of lymphoma in RA is related to the cumulative burden of inflammation, TNFi may conversely reduce the risk of lymphoma by decreasing the burden of inflammation.	27502891
Inflammation	Altered Intercellular Communication	Since Japanese dialysis patients are generally less inflamed than those in Western countries, inflammation may modify the association between serum ferritin and the adverse outcomes.	27503345
Inflammation, Depression, CTCAE, Sleep disturbances	Altered Intercellular Communication	An increasing body of evidence links the occurrence of sleep continuity disturbances with increased inflammation and both sleep disturbances and inflammation are associated with clinical depression.	27503474
Inflammation, Carcinogenesis	Altered Intercellular Communication	Chronic inflammation has been implicated in colorectal carcinogenesis.	27504605
Inflammatory abnormality of the eye, Epithelial	Altered Intercellular Communication	A successful clinical outcome, defined as a stable ocular surface without epithelial defects, a clear cornea without fibrovascular tissue invasion at the pupillary area, and no or mild ocular surface inflammation, was obtained in 15 of 20 eyes (75 %).	27507558
Inflammation, Pruritus	Altered Intercellular Communication	Air pollution-induced inflammation could occur in the skin and aggravate skin symptoms such as pruritus or impair epidermal barrier function.	27507591
Inflammation, Squamous cell carcinoma	Altered Intercellular Communication	White adipose tissue inflammation and cancer-specific survival in patients with squamous cell carcinoma of the oral tongue.	27508351
Inflammation, Squamous cell carcinoma	Altered Intercellular Communication	We investigated whether WAT inflammation in the tongue impacts survival in patients with squamous cell carcinoma (SCC) of the oral tongue.	27508351
Inflammation, Vascular Invasion Assessment, Neoplasms	Altered Intercellular Communication	Overall, 49 of 125 patients (39%) had tongue WAT inflammation, which was associated with higher body mass index, increased tumor thickness, and vascular invasion (P < .05).	27508351
Inflammation, Tissue Adhesions	Altered Intercellular Communication	In the LCBDE group, 4 (6.6%) patients were converted due to heavy inflammation and severe adhesions.	27509535
Inflammation	Altered Intercellular Communication	Neutrophil-lymphocyte ratio (NLR), an indicator of inflammation, has been lately demonstrated as a prognostic factor and an indicator of disease activity in various diseases.	27510180
Inflammation	Altered Intercellular Communication	* T1w-3D mVISTA visualized CWT/CCW as correlates of mural inflammation in LVV.	27510630
Trauma, Nervous System	Altered Intercellular Communication	It has been well established that inflammatory signaling pathways in ALS converge at NF-kB to promote neuronal damage.	27512062
Inflammation, Obesity, Abdominal, Hypertension, CTCAE	Altered Intercellular Communication	Vegetarian diet reduces the risk of hypertension independent of abdominal obesity and inflammation: a prospective study.	27512965
Inflammation, Hypertension, CTCAE, Obesity	Altered Intercellular Communication	A vegetarian diet may prevent elevation of blood pressures and lower the risk for hypertension through lower degrees of obesity, inflammation, and insulin resistance.	27512965
Inflammation, Obesity, Abdominal, Hypertension, CTCAE	Altered Intercellular Communication	Vegetarian diets may protect against hypertension beyond lower abdominal obesity, inflammation, and insulin resistance.	27512965
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Elevated estimated arterial age is associated with metabolic syndrome and low-grade inflammation.	27512974
Cataract, Inflammation, Pain Distress Question	Altered Intercellular Communication	Topical nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for the prevention and treatment of inflammation and pain following cataract surgery.	27513223
Inflammation, ovarian neoplasm	Altered Intercellular Communication	Thus, excessive inflammation and oxidative stress caused an increase in DNA damage and enhanced Hcy content, leading to development of ovarian cancer.	27513230
Inflammation, Asthma, Exacerbation	Altered Intercellular Communication	This indicates that there is a value in measuring both FeNO and systemic eosinophilic inflammation in patients with asthma to identify individuals at high risk of exacerbations.	27513280
Inflammation, Asthma	Altered Intercellular Communication	FeNO and S-ECP are markers for inflammation in asthma, but are dependent on different inflammatory pathways and weakly correlated.	27513280
Airway structure, Asthma	Altered Intercellular Communication	Rhinovirus (RV) infection in asthma induces varying degrees of airway inflammation (e.g.	27513438
Pyroglyphidae, Pneumonitis	Altered Intercellular Communication	Tollip knockout and wild-type mice were challenged with house dust mite (HDM) and infected with RV1B to determine lung inflammation and antiviral response.	27513438
Pneumonitis	Altered Intercellular Communication	Upon HDM and RV1B, Tollip knockout (vs. wild-type) mice demonstrated higher levels of lung neutrophilic inflammation and viral load, but lower levels of antiviral gene expression.	27513438
Inflammation	Altered Intercellular Communication	The inadvertent application on the thin skin of the cheekbones led to a pronounced inflammation.	27513756
Inflammation, Conjunctivitis	Altered Intercellular Communication	With topical steroids followed by fusidic acid, both conjunctivitis and skin inflammation resolved within a few days.	27513756
Inflammation	Altered Intercellular Communication	BMI and fat distribution showed expected associations to inflammation biomarkers, but paradoxical relations between fat indices, and MetSyn components and biomarkers were seen.	27513810
Inflammation, Obesity	Altered Intercellular Communication	Effect of Obesity on Acute Ozone-Induced Changes in Airway Function, Reactivity, and Inflammation in Adult Females.	27513854
Inflammation, Obesity	Altered Intercellular Communication	Animal models suggest that obesity enhances ozone-induced airway reactivity and inflammation.	27513854
Airway structure, Obesity	Altered Intercellular Communication	However, acute ozone-induced airway reactivity to methacholine and airway inflammation did not differ by obesity at the exposure and exercise levels used.	27513854
Keratitis, Peroneal Neuropathies	Altered Intercellular Communication	We hypothesize that poor Ex-PRESS shunt positioning can act as a nidus for corneal inflammation, resulting in corneal neuropathy and lowering of the nociception threshold.	27513904
Inflammation	Altered Intercellular Communication	Knowledge of sepsis-related end-organ inflammation in vivo is limited.	27514616
palladium, Inflammation	Altered Intercellular Communication	An easy and inexpensive test of an NLR greater than 3 could be used as a measure of inflammation instead of HSCRP in both PD and hemodialysis patients.	27514767
Kidney Failure, Chronic, Inflammation, Electrocardiogram: left ventricle hypertrophy (finding)	Altered Intercellular Communication	Inflammation, Left Ventricular Hypertrophy, and Mortality in End-stage Renal Disease.	27514769
Inflammation, Ventricular hypertrophy, Cardiovascular system	Altered Intercellular Communication	Inflammation, pulse pressure, and left ventricular hypertrophy are interrelated and all contribute to mortality and cardiovascular death risk among dialysis patients.	27514769
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer's disease.	27514990
Refractory anemias, Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain persists in people with treated RA, even in those for whom inflammation responds to treatment.	27515300
Communicable Diseases, Inflammation, septic, Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammations are a particular type of chronic septic or aseptic inflammation, in which infectious or non-infectious agents are difficult to eliminate by the immune system.	27516029
Inflammation, Granulomatous, Granuloma	Altered Intercellular Communication	At cutaneous level, this pattern of granulomatous reaction is characterized by a chronic inflammation with formation of granulomas consisting of a variable number of histiocytes, multinucleated giant cells and lymphocytes.	27516029
Granulomatous dermatitis, Inflammation, Neoplasms	Altered Intercellular Communication	Granulomatous dermatoses should be differentiated from other primary or secondary lesions affecting the skin such as inflammation or tumors.	27516029
Communicable Diseases, Inflammation, septic, Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammations are a particular type of chronic septic or aseptic inflammation, in which infectious or non-infectious agents are difficult to eliminate by the immune system.	27516029
Arteritis	Altered Intercellular Communication	Blood supply blockage can occur with or without arterial inflammation.	27516038
Airway structure, Asthma, Obstruction	Altered Intercellular Communication	Computer-aided lung sound analysis (LSA) has been reported to be useful for evaluating airway inflammation and obstruction in asthma patients.	27516132
Chronic kidney disease mineral and bone disorder, Inflammation	Altered Intercellular Communication	Metabolic and inflammation biomarkers potentially linked to CKD-MBD were also analysed.	27519971
bleomycin/cisplatin/vinblastine protocol, Inflammation, SLC25A20 gene, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus	Altered Intercellular Communication	Low VBD was independently associated with higher CAC score (>100 AUs) after adjustment for age, gender, diabetes, CVD, inflammation and cohorts.	27519971
bleomycin/cisplatin/vinblastine protocol, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus	Altered Intercellular Communication	In Cox proportional hazards analysis, low VBD was independently associated with all-cause mortality after adjustment for age, gender, diabetes, CVD, inflammation and subjective global assessment (SGA).	27519971
Malignant neoplasm of larynx, Palsy	Altered Intercellular Communication	The participants (N = 80 larynx cancer, N = 32 recurrent palsy, N = 23 dysfunctional, N = 75 degenerative/inflammation, N = 19 various) were included consecutively at the laryngology clinic at Haukeland University Hospital.	27520510
Inflammation, MYELODYSPLASTIC SYNDROME, Miller Dieker syndrome	Altered Intercellular Communication	Inflammation has an essential role in the pathogenesis of myelodysplastic syndromes (MDS).	27521329
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We measured HTGC, body composition, circulating markers of inflammation, fibrosis, and glucose tolerance at baseline and at 12 weeks.	27521509
Inflammation, Maternal infection	Altered Intercellular Communication	Our objective was to identify risk factors associated with maternal infections and placental inflammation in pregnant adolescents attending an urban adolescent maternity clinic.	27521899
Inflammation, Infection	Altered Intercellular Communication	The prevalence of maternal infections and placental inflammation was determined and potential risk factors were identified.	27521899
Presenile dementia, Inflammation	Altered Intercellular Communication	Vascular risk factors, including inflammation, may contribute to dementia development.	27522059
Inflammation	Altered Intercellular Communication	The combined inflammation z-score was significantly associated with memory and psychomotor speed (p < .01).	27522059
Inflammation	Altered Intercellular Communication	Our results suggest that total inflammation is associated with memory and psychomotor speed.	27522059
Inflammation, vascular inflammations	Altered Intercellular Communication	In particular, systemic inflammation, vascular inflammation, and altered endothelial function may play roles in domain-specific cognitive decline of nondemented individuals.	27522059
Inflammation	Altered Intercellular Communication	Thus, induction of the immunoproteasome was identified as a pathomechanism underlying inflammation in IIMs.	27522114
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The mean tissue concentrations of all 10 metals and non-metal were significantly lower in NP patients than in healthy controls (P < 0.05).TEM and SEM revealed changes in the mucosal ultrastructure in NP with progressive fibrosis, devascularisation, and inflammation.	27522207
Inflammation, Atherosclerosis	Altered Intercellular Communication	The objective of the study was to determine if the association between airflow obstruction and markers of atherosclerosis is mediated by systemic inflammation.	27522264
Inflammation, Calcification of the aorta, Leukocytes	Altered Intercellular Communication	After adjusting for population characteristics, Framingham cardiovascular risk factors and markers of systemic inflammation (WBC and CRP), there was a significantly increased aortic arch and distal aorta calcification and higher CIMT measurement in individuals with airflow obstruction compared to individuals without airflow obstruction.	27522264
Inflammation, Calcification of the aorta, Leukocytes	Altered Intercellular Communication	After adjusting for population characteristics, Framingham cardiovascular risk factors and markers of systemic inflammation (WBC and CRP), there was a significantly increased aortic arch and distal aorta calcification and higher CIMT measurement in individuals with airflow obstruction compared to individuals without airflow obstruction.	27522264
Inflammation, Leukocytes, Atherosclerosis	Altered Intercellular Communication	Systemic inflammation (WBC and CRP) does not appear to mediate the association between airflow limitation and atherosclerosis.	27522264
Inflammation, Leukocytes, Atherosclerosis	Altered Intercellular Communication	Only airflow limitation and not systemic inflammation (WBC and CRP) appears to be an independent predictor of atherosclerosis.	27522264
Diabetic Nephropathy, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Serum microRNA-217 may be involved in the development of diabetic kidney disease by promoting chronic inflammation, renal fibrosis, and angiogenesis.	27522360
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Calcium supplementation and inflammation increase mortality in rheumatoid arthritis: A 15-year cohort study in 609 patients from the Oslo Rheumatoid Arthritis Register.	27522465
Inflammation, Hemorrhage	Altered Intercellular Communication	Massive amyloid deposits were present in the vessels, and collapsed internal elastic laminae with lymphocyte infiltration were observed at the site of amyloid deposits in the bronchial artery, suggesting that deposits with inflammation might cause the collapse of the bronchial artery and lead to hemorrhage.	27522614
Inflammation, Amyloidosis, Heart failure	Altered Intercellular Communication	In amyloidosis patients who suffer heart failure, there is the potential for vascular collapse caused by the accumulation of amyloid deposits with inflammation.	27522614
Inflammation, Metabolic Diseases, pathologic cytolysis, Arthritis, Cholestasis	Altered Intercellular Communication	High activity of hepatocytes cytolysis, cholestasis, inflammation, metabolic disorders let us considerpsoriatic arthritis as a severe clinical stage psoriatic disease when the hepatobiliary system, in turn, is one of the main target organs in systemic psoriatic process.	27522710
Inflammation, Neoplasms	Altered Intercellular Communication	The mRNA expression of specific biomarkers (SGLT1, SGLT5, GIP, GLP, LAT1, LAT2, and NPC1L1) in the mucosa was compared among three patient groups: Inflammation, Tumor, and Control.	27522989
Inflammation	Altered Intercellular Communication	Premenopausal women were at an increased risk of lobular inflammation, hepatocyte ballooning, and Mallory-Denk bodies than men and also at an increased risk of lobular inflammation and Mallory-Denk bodies than postmenopausal women (P < .01).	27523635
Ischemia, Inflammation	Altered Intercellular Communication	Post-cardiac arrest syndrome (PCAS) is characterized by whole-body ischemia triggering systemic inflammation and damage of the endothelium.	27523954
Cardiac Arrest, Inflammation, Corneal Endothelial Cell Loss	Altered Intercellular Communication	This study investigated the relationship between systemic inflammation, endothelial damage and severity of PCAS and the association between endothelial damage and outcome after out-of-hospital cardiac arrest (OHCA).	27523954
Inflammation, Comatose, SLITRK1 wt Allele	Altered Intercellular Communication	In comatose survivors after OHCA treated with TTM, systemic inflammation was associated with endothelial activation and endothelial damage.	27523954
ARCN1 gene, Inflammation	Altered Intercellular Communication	Certain individual circulating cytokines (particularly TNFa and IL-1b) were significantly elevated in concentration in the serum of particular COPD patients (and some current/ex-smokers without COPD) and may serve as markers of particularly significant systemic inflammation.	27524865
Facilitation	Altered Intercellular Communication	Unlike VD, the hyperfacilitation found at baseline in VCI-ND patients suggests enhanced glutamatergic neurotransmission that might contribute to the preservation of cognitive functioning.	27525127
Granulomatous inflammation	Altered Intercellular Communication	and usually presents as a chronic, suppurative and granulomatous inflammation with a propensity to mimic malignant conditions.	27526941
Dental caries, Pulpitis	Altered Intercellular Communication	Moreover, complete removal of carious dentin in deep carious lesions often leads to pulp exposure and root canal treatment, despite the absence of irreversible pulp inflammation.	27527342
ovarian neoplasm, Inflammation, Malignant Neoplasms, Neoplasms	Altered Intercellular Communication	Ovarian cancer is a highly complex heterogeneous malignancy in respect of tumor anatomy, tumor microenvironment including pro-/antitumor immunity and inflammation; still, it is generally treated as single disease.	27527602
Inflammation, Atherosclerosis, Marfan Syndrome, Traumatic injury, Hypertension, CTCAE	Altered Intercellular Communication	It is most commonly associated with trauma or surgery, less commonly with atherosclerosis, inflammation, hypertension or Marfan's syndrome.	27527829
Inflammation	Altered Intercellular Communication	Critically, hormesis could improve mitochondrial quantum efficiency, improving the ATP/ROS ratio, whereas inflammation, which is tightly associated with the aging process, might do the opposite.	27528758
Inflammation, Uterine Cervicitis, Mucous retention cyst of cervix uteri	Altered Intercellular Communication	According to our study, among misdiagnosed patients, nabothian cysts and cervicitis were the most common histological findings; FDPs were more often symptomatic (p < 0.001) and coexisted more frequently with inflammation or ulceration (p < 0.001).	27529156
Inflammation, Ulceration, CTCAE, Ulcerative Colitis	Altered Intercellular Communication	Colonoscopy revealed inflammation and ulceration with biopsy consistent with ulcerative colitis (UC).	27530224
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, AAVS1 gene	Altered Intercellular Communication	In recent literature, antineutrophil cytoplasmic autoantibodies (ANCA) positivity has been reported in various inflammatory conditions other than ANCA-associated vasculitis (AAV).	27530224
Inflammation, Mitochondria	Altered Intercellular Communication	Inflammation in adult women with a history of child maltreatment: The involvement of mitochondrial alterations and oxidative stress.	27530300
Inflammation	Altered Intercellular Communication	The experience of maltreatment during childhood is associated with chronic low-grade inflammation in adulthood.	27530300
Inflammation	Altered Intercellular Communication	To this end, we hypothesized that alterations in immune cell mitochondrial functioning and oxidative stress might be at the interface between the association of maltreatment experiences during childhood and inflammation.	27530300
Inflammation, Thrombosis, ASAH1 gene, Anemia	Altered Intercellular Communication	Further evaluation of this association is warranted as it may shed light on mechanistic relations between anemia, inflammation, and thrombosis after aSAH.	27530692
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Chronic adventitial inflammation, vasa vasorum expansion, and 5-lipoxygenase up-regulation in irradiated arteries from cancer survivors.	27530979
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	These results point to targeting the 5-LO/leukotriene pathway as a therapeutic adjunct to prevent late adverse vascular effects of radiotherapy.-Halle, M., Christersdottir, T., Back, M. Chronic adventitial inflammation, vasa vasorum expansion, and 5-lipoxygenase up-regulation in irradiated arteries from cancer survivors.	27530979
Inflammation, Takayasu Arteritis	Altered Intercellular Communication	These processes may influence arterial inflammation and remodelling in Takayasu arteritis (TA).	27531191
Inflammation, Hypertensive (finding)	Altered Intercellular Communication	Markers of systemic or local inflammation correlated with higher CgA-FRs and VS-1 in normotensive patients and with higher CgA439 in hypertensive patients.	27531191
Inflammation, Obesity	Altered Intercellular Communication	The n-3 polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) may reduce low-grade inflammation associated with obesity.	27531277
Inflammation	Altered Intercellular Communication	Administration of anti-tuberculosis chemotherapy caused: (a) diminution of inflammation, (b) diminution of the size of local fusiform injury, and (c) clinical improvement.	27531321
Inflammation, Bronchiolitis	Altered Intercellular Communication	cDCs accumulate in the lower airways during RSV bronchiolitis, are activated systemically and may, through activation of T cells, NK T cells and NK cells, contribute to RSV-induced inflammation and disease.	27531529
Swelling	Altered Intercellular Communication	Differences of weight between right and left ears were measured by ear swelling method and anti-inflammation experiment.	27534086
Viremia, Hepatitis	Altered Intercellular Communication	All Bama miniature swine that were infected with HEV genotypes 3 and 4 exhibited significant HEV viremia, shedding, anti-HEV antibody responses and partial liver inflammation.	27534702
Mucous Membrane, Inflammation	Altered Intercellular Communication	Most studies show a relatively high prevalence of mucosal atrophy and inflammation in treated patients, a finding which have led to a concept of non-responsive CD.	27534885
Inflammation, Cardiovascular morbidity	Altered Intercellular Communication	Heart rate (HR), heart rate variability (HRV), and inflammation are all associated with cardiovascular morbidity and mortality.	27534940
Inflammation, Necrosis	Altered Intercellular Communication	High-mobility group box 1 (HMGB1) is a nuclear protein that triggers inflammation when released from activated immune or necrotic cells and drives the pathogenesis of various infectious agents.	27535058
Airway structure, Inflammatory disorder	Altered Intercellular Communication	Although HMGB1 has been implicated in many inflammatory diseases, its role in RSV-induced airway inflammation has not been investigated.	27535058
Airway structure	Altered Intercellular Communication	HMGB1 is a ubiquitous redox-sensitive multifunctional protein that serves as both a DNA regulatory protein and an extracellular cytokine signaling molecule that promotes airway inflammation as a damage-associated molecular pattern.	27535058
Inflammation, Antiphospholipid Syndrome, atherosclerotic	Altered Intercellular Communication	NTPV-associated aPL might be distinct from classic antiphospholipid syndrome and should be considered in aPL-positive patients who present with vascular occlusions of medium-sized vessels in the absence of atherosclerotic risk factors and systemic or local inflammation.	27535710
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Our aim was to assess mucosal miRNA expression in IBD and the correlation with intestinal inflammation.	27536783
Inflammatory abnormality of the eye	Altered Intercellular Communication	New Zealand has a multicultural population with a wide spectrum of ocular inflammation that varies with ethnicity and age.	27537334
Inflammation, Pulmonary Hypertension	Altered Intercellular Communication	The granulomatous inflammation found in the histology supports a sarcoid-like reaction due to pulmonary hypertension in the context of the BMPR2 mutation.	27537724
Inflammation, Brain Injuries, Cerebral Hemorrhage	Altered Intercellular Communication	Inflammation is involved in pathophysiological mechanisms underlying secondary brain injury after intracerebral hemorrhage.	27538613
Inflammation, Cerebral Hemorrhage	Altered Intercellular Communication	This study was designed to investigate whether plasma galectin-3 levels are related to the inflammation, severity and prognosis following intracerebral hemorrhage.	27538613
Inflammation, Brain hemorrhage, Cerebral Hemorrhage	Altered Intercellular Communication	Elevated plasma galectin-3 levels are strongly associated with the inflammation, severity and poor prognosis after intracerebral hemorrhage, indicating galectin-3, involved in brain inflammation, might have the potential to be a prognostic biomarker for hemorrhagic stroke.	27538613
Inflammation	Altered Intercellular Communication	By clarifying joint inflammation in an IA cohort with overall low ESR, ultrasonography of physician-selected joints can improve clinical assessment, resulting in treatment modification.	27538766
Diffuse Large B-Cell Lymphoma, Chronic inflammation	Altered Intercellular Communication	We report an 80 year old female patient who developed a DLBCL with chronic inflammation in association to a metallic implant in the left knee.	27539226
Diffuse Large B-Cell Lymphoma, Chronic inflammation	Altered Intercellular Communication	This report challenges the concept of DLBCL associated with chronic inflammation and raises the question of other pathogenetic factors involved in the pathogenesis of this rare disease.	27539226
Pain Distress Question	Altered Intercellular Communication	Chronic elevation of the pain neurotransmitter substance P (SP) sensitizes pain nociceptors.	27539682
Unknown (origin) (qualifier value), Inflammation, Pain Distress Question	Altered Intercellular Communication	Hence, the burning sign may be associated with pain and inflammation in idiopathic FS.	27539943
Inflammation, Asthma	Altered Intercellular Communication	Patients with both systemic inflammation and comorbidities showed poorest outcome of asthma.	27540019
Renal Insufficiency, Inflammation, Choline Dehydrogenase, Mitochondrial, myocardial injury	Altered Intercellular Communication	Galectin-3 does not independently predict recurrent cardiovascular events in patients with established CHD after adjustment for markers of hemodynamic stress, myocardial injury, inflammation, and renal dysfunction.	27540030
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Our findings indicate that mechanisms related to inflammation, including macrophage activation and adipocyte metabolism, may play a role in changes in glucose homeostasis in individuals at high risk of type 2 diabetes mellitus.	27541014
Inflammation, Astigmatism	Altered Intercellular Communication	The gold weight was removed in four patients (10.5%), due to chronic inflammation in three and due to mild astigmatism in one.	27541938
Inflammation, Traumatic injury	Altered Intercellular Communication	Marjolin ulcers (MU) classically present as an aggressive SCC in area of chronic inflammation, which has been previously correlated to constant pressure, repetitive trauma, or non-healing wounds in other areas of the body.	27541940
Colitis	Altered Intercellular Communication	Finally, the colonic cytokine levels and disease scores of the AdTr model indicated reduced levels of colonic inflammation in liraglutide-dosed animals.	27542128
Inflammation	Altered Intercellular Communication	Non-infectious uveitis is a potentially sight-threatening ocular disorder caused by chronic inflammation and its complications.	27542302
Inflammation, Hodgkin Disease	Altered Intercellular Communication	The presence of CD30-expressing Hodgkin-like cells with a background of inflammation and eosinophils in a young adolescent is usually diagnostic of classical Hodgkin lymphoma.	27543511
PROS1 gene, Inflammation, Psoriasis, Tumor necrosis, Arthritis, Psoriatic	Altered Intercellular Communication	Cytokines such as tumour necrosis factor (TNF)-a, interleukin (IL)-12, interferon (IFN)-g, IL-23 and, more recently, IL-9, have been implicated in the initiation/maintenance of inflammation in psoriasis and psoriatic arthritis (PsA).	27543964
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays an important role on every stage of atherosclerosis.	27544604
nervous system disorder, Inflammation, Autonomic nervous system	Altered Intercellular Communication	CONCLUSIONS Chronic inflammation in the course of CD may lead to autonomic nervous system impairment and development of neurologic disorders.	27545437
Heart failure	Altered Intercellular Communication	Parathyroid hormone is associated with heart failure with preserved ejection fraction.	27546695
Inflammation, Vertebrobasilar Insufficiency, Atherosclerosis	Altered Intercellular Communication	Vertebrobasilar insufficiency and gamma-glutamyltransferase: An emerging relationship demonstrating inflammation and atherosclerosis.	27546696
Inflammation, Vertebrobasilar Insufficiency, eVLP CMV gB-pp65 Plus GM-CSF VBI-1901, Atherosclerosis	Altered Intercellular Communication	Vertebrobasilar insufficiency (VBI) is a pathology arising from the reduction in flow rate of vertebral arteries and mainly caused by inflammation and atherosclerosis.	27546696
Inflammation, Atherosclerosis	Altered Intercellular Communication	Gamma-glutamyltransferase (GGT) is a marker which has been recently recognized as a marker of inflammation and atherosclerosis.	27546696
Atherosclerosis	Altered Intercellular Communication	In addition, higher GGT level was an independent risk factor for the presence of vertebrobasilar system inflammation and atherosclerosis (Tab.	27546696
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Systemic inflammation and painful joint burden in osteoarthritis: a matter of sex?	27546883
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	There may be a dose-response association between painful joint burden in OA and systemic inflammation, and it appears the association is sex-specific, which may in part explain inconsistent findings in the literature.	27546883
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Our results underline the importance of showing sex-specific associations in OA, especially when studying the influence of inflammation.	27546883
Nonalcoholic Steatohepatitis, Inflammation, Non-alcoholic Fatty Liver Disease, Fatty Liver Disease	Altered Intercellular Communication	The progression of non-alcoholic fatty liver disease (NAFLD) to non-alcoholic steatohepatitis (NASH) is associated with inflammation.	27548138
Inflammation, Fibrosis Assessment, Fatty Liver Disease	Altered Intercellular Communication	In male patients weak positive correlations with inflammation, fibrosis and NASH score were identified.	27548138
Inflammation, Aortic valve calcification	Altered Intercellular Communication	Inflammation is an important factor in the pathogenesis of calcific aortic stenosis (AS).	27548384
Sepsis, Inflammation	Altered Intercellular Communication	ANG1 is a Tie2 agonist that promotes vascular stabilization in inflammation and sepsis, whereas ANG2 is a context-dependent Tie2 agonist or antagonist.	27548530
Inflammation, Periodontitis	Altered Intercellular Communication	However, many of these potential OSCC salivary biomarkers are also involved in chronic inflammation, and whether the levels of these biomarkers could be affected by the presence of chronic periodontitis was not known.	27549383
Inflammation, pyloric region	Altered Intercellular Communication	Because of the corrosive effect, he developed severe inflammation of the upper gastro intestinal tract with narrowing of esophagus and pyloric region, requiring feeding jejunostomy.	27549430
Gestational Diabetes, Inflammation	Altered Intercellular Communication	Elevated GCF IL-10 levels may be a consequence of higher levels of inflammation as indicated by higher PI and BOP in the GDM group.	27552375
Inflammation, Albuminuria, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation plays an important role in albuminuria in type 2 diabetes mellitus (T2DM).	27552538
Inflammation	Altered Intercellular Communication	Aging, not age-associated inflammation, determines blood pressure and endothelial responses to acute inflammation.	27552645
Inflammation	Altered Intercellular Communication	Aging is characterized by a state of chronic, low-grade inflammation that impairs vascular function.	27552645
Inflammation	Altered Intercellular Communication	Acute inflammation causes additional decrements in vascular function, but these responses are not uniform in older compared with younger adults.	27552645
Inflammation	Altered Intercellular Communication	We hypothesized age-related differences in the vascular responses to acute inflammation, but that older adults with low baseline inflammation would respond similarly to younger adults.	27552645
Inflammation	Altered Intercellular Communication	Aging, not age-related chronic, low-grade inflammation, determines the vascular responses to acute inflammation.	27552645
Communicable Diseases, Inflammation, Lung diseases, Lung Injury	Altered Intercellular Communication	Treatment of lung disease to reduce the impact of infection, inflammation and subsequent lung injury is therefore of major importance.	27552791
Neoplasms	Altered Intercellular Communication	The Glasgow prognostic score (GPS) is an inflammation-based score based on albuminemia and C-reactive protein concentration proved to be associated with cancer-specific survival in several neoplasms.	27553499
Inflammation	Altered Intercellular Communication	Weight discrimination was associated with lipid/metabolic dysregulation (1.56; 95 % CI 1.02, 2.40), glucose metabolism (1.99; 95 % CI 1.34, 2.95), and inflammation (1.76; 95 % CI 1.22, 2.54), but no other systems.	27553775
Inflammation, Arthritis, Gouty, Synovial Neoplasm	Altered Intercellular Communication	Pathology +- microbiology findings for these 107 conclusive biopsies comprised synovial tumour (n = 30, 28 %), synovial infection (n = 18, 17 %), synovial inflammation (n = 45, 42 %), including gouty arthritis (n = 3), and no abnormality (n = 14, 13 %).	27553941
atherosclerotic	Altered Intercellular Communication	This possible contribution of immune mediators to an atherosclerotic process probably relates to the inflammaging process.	27554076
Airway structure, Steroid-resistant nephrotic syndrome	Altered Intercellular Communication	Our findings reveal age differences in LT and Wnt pathways during airway inflammation and identify a steroid-resistant cascade of Wnt5a, Tgm2, and LTs, which might represent a therapeutic target for airway inflammation and remodeling.	27554815
Inflammation	Altered Intercellular Communication	We sought to characterize molecularly cutaneous inflammation and its correlation with clinical and barrier characteristics.	27554821
Inflammation, Ichthyoses, Dehydration	Altered Intercellular Communication	These markers also significantly correlated with transepidermal water loss, suggesting a link between the barrier defect and inflammation in patients with ichthyosis.	27554821
Inflammation, Periodontal Diseases	Altered Intercellular Communication	Periodontal disease is associated with increased systemic inflammation in stable cardiovascular patients.	27556206
Inflammation	Altered Intercellular Communication	The pharmacological activities of many Punica granatum L. components suggest a wide range of clinical applications for the prevention and treatment of diseases where chronic inflammation is believed to play an essential etiologic role.	27556440
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Hematological biomarkers of inflammation such as the neutrophil-to-lymphocytic rate have been reported as predictors of survival in a variety of cancers.	27556669
Inflammation	Altered Intercellular Communication	AI correlates with CLE markers of acute and chronic inflammation.	27557471
Inflammation	Altered Intercellular Communication	Normal level of apoptosis and DNase I activity simultaneously reduce the level of acute inflammation in CLE.	27557471
Squamous cell carcinoma of esophagus	Altered Intercellular Communication	A novel inflammation-based prognostic score for patients with esophageal squamous cell carcinoma: the c-reactive protein/prognostic nutritional index ratio.	27557504
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation plays a critical role in cancer prognosis.	27557504
Squamous cell carcinoma of esophagus	Altered Intercellular Communication	In the current study, we proposed a novel inflammation-based prognostic score, named c-reactive protein/prognostic nutritional index ratio (CRP/PNI ratio), for predicting the prognosis for patients with resectable esophageal squamous cell carcinoma (ESCC).	27557504
Inflammation	Altered Intercellular Communication	Both adipose tissue and monocyte/macrophages contribute to the increased inflammation in MetS.	27557909
Necrotizing granulomatous inflammation, Squamous cell carcinoma	Altered Intercellular Communication	Initially this was thought to be an invasive squamous cell carcinoma but a biopsy showed histological features consistent with necrotizing granulomatous inflammation.	27558192
Inflammatory Bowel Diseases, Crohn Disease, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Inflammatory bowel disease (IBD), manifesting as Crohn's disease (CD) and ulcerative colitis (UC), is characterized by recurring episodes of inflammation in gastrointestinal tract, in which aberrant production of regulatory cytokine interleukin-10 (IL-10) presumably plays important role.	27558476
Pain Distress Question, Inflammation	Altered Intercellular Communication	There is limited evidence that ginger powder consumption can relieve pain and inflammation due to specific anti-inflammatory phytochemical constitutents.	27559855
Sarcoma, Inflammation	Altered Intercellular Communication	Moreover, it provides further indications regarding the potential association between foreign body reaction on the basis of chronic inflammation and sarcoma development.	27559958
Inflammation, Osteoporotic Fractures	Altered Intercellular Communication	There is still debate on whether high uric acid increases bone mineral density (BMD) against osteoporotic fracture or bone resorption caused by gout inflammation.	27559970
Inflammation, Asthma	Altered Intercellular Communication	Peroxisome proliferator-activated receptor gamma (PPAR-g) is a nuclear receptor that modulates inflammation in models of asthma.	27560168
Inflammation, Sample Size Calculation	Altered Intercellular Communication	CD8 + T cells may significantly contribute to inflammation in SSc.	27560622
Inflammation	Altered Intercellular Communication	In obese individuals, visceral adipose tissue (VAT) is the seat of chronic low-grade inflammation (metaflammation), but the mechanistic link between increased adiposity and metaflammation largely remains unclear.	27561727
Inflammation, Obesity	Altered Intercellular Communication	Thus, this study reveals a pathway that drives adipose tissue inflammation and consequent IR in obesity.	27561727
Inflammation, Pain Distress Question	Altered Intercellular Communication	Inflammation and pain were determined using serum high sensitivity C-reactive protein (hs-CRP) and a visual analogue scale (VAS), respectively.	27561790
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a chronic inflammatory condition associated with an increased risk of cardiovascular mortality.	27561790
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a chronic inflammatory condition associated with increased cardiovascular morbidity/mortality and an incompletely understood pathophysiology.	27561790
Dermatomyositis, Paresis, Autoimmune myopathy, Myositis	Altered Intercellular Communication	Dermatomyositis is an autoimmune myopathy characterized by proximal muscle weakness, muscle inflammation, and typical skin findings.	27561848
ARCN1 gene, Inflammation	Altered Intercellular Communication	Reducing ADAM17 and EGFR activity could therefore be a therapeutic approach for the tissue remodeling and inflammation observed in COPD.	27561911
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The role of sphingosine 1-phosphate (S1P) in liver fibrosis or inflammation was not fully examined in human.	27562371
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In conclusion, S1P may be actively generated, transported to outside the cells, and bind to its specific receptor in human liver to play a role in fibrosis or inflammation.	27562371
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Association of inflammation with specific symptoms of depression in a general population of older people: The English Longitudinal Study of Ageing.	27562420
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	In this context, inflammation has an important role in the development and progression of many malignancies.	27564278
Inflammation, Nasopharyngeal carcinoma	Altered Intercellular Communication	Increased Risk of Nasopharyngeal Carcinoma with Increasing Levels of Diet-Associated Inflammation in an Italian Case-Control Study.	27564524
Inflammation, Nasopharyngeal carcinoma	Altered Intercellular Communication	Components of diet can modulate inflammation and therefore may have an important role in the development of nasopharyngeal carcinoma (NPC).	27564524
Injury of integument	Altered Intercellular Communication	Furthermore, we show that on acute skin injury in both human and murine settings, this transition occurs quickly, consistent with a response to inflammatory signaling.	27565038
Pancreatitis	Altered Intercellular Communication	A follow-up MRCP revealed a swollen pancreas and pancreatic inflammation.	27565931
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Connections exist between inflammation and cancer, for example with regard to disease progression and prognosis.	27566075
Inflammation	Altered Intercellular Communication	Nitric oxide (NO) pathway plays a major role in the development and advancement of inflammation.	27566088
Inflammation, Neoplasms	Altered Intercellular Communication	Deep study of RUNX3 inflammation signaling could help in understanding inflammation and immune activation in the tumor microenvironment.	27566570
Communicable Diseases	Altered Intercellular Communication	CD57+ T cells have been associated with inflammatory conditions, but their potential role in the response against infectious disease and vaccination should now be investigated.	27566833
Optimism, Inflammation, Fracture, Hostility	Altered Intercellular Communication	Traits of optimism and cynical hostility are features of personality that could influence the risk of falls and fractures by influencing risk-taking behaviors, health behaviors, or inflammation.	27566996
Sjogrens Syndrome	Altered Intercellular Communication	Interleukin-15 as a potential new target in Sjogren's syndrome-associated inflammation.	27567226
allergic inflammation	Altered Intercellular Communication	Pentraxin 3 deletion aggravates allergic inflammation through a TH17-dominant phenotype and enhanced CD4 T-cell survival.	27567326
Communicable Diseases, Inflammation	Altered Intercellular Communication	It is produced at sites of infection and inflammation by both structural and inflammatory cells.	27567326
Asthma, allergic inflammation	Altered Intercellular Communication	We sought to determine the effect of Ptx3 deletion on ovalbumin (OVA)-induced allergic inflammation in a murine model of asthma.	27567326
Respiratory Hypersensitivity, Eosinophilic inflammation	Altered Intercellular Communication	Mice lacking PTX3 have exaggerated neutrophilic/eosinophilic lung inflammation, mucus production, and airway hyperresponsiveness in an experimental model of OVA-induced asthma.	27567326
Respiratory Hypersensitivity, allergic inflammation, Pneumonitis	Altered Intercellular Communication	Altogether, PTX3 deficiency results in augmented airway hyperresponsiveness, mucus production, and IL-17A-dominant pulmonary inflammation, suggesting a regulatory role of PTX3 in the development of allergic inflammation.	27567326
Inflammation, Data types - Address	Altered Intercellular Communication	The growing appreciation of the importance of inflammation in early AD has focused attention on inflammatory biomarkers in cerebrospinal fluid or plasma; however, non-specific inflammation markers have disappointed to date.	27567854
Inflammation, Data types - Address	Altered Intercellular Communication	Complement, a core system in innate immune defense and potent driver of inflammation, has been implicated in pathogenesis of AD based on a confluence of genetic, histochemical, and model data.	27567854
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Increasing evidence indicates that inflammation may play important roles in tumorigenesis and progression, and an elevated peripheral monocyte count predicts a poor prognosis in various types of malignancies.	27569002
Inflammation, Cardiovascular Diseases, Dyslipidemias, Decreased renal function, Hypophosphatemia	Altered Intercellular Communication	In addition to decreased renal function, dyslipidemia, inflammation, and continuing hypophosphatemia were also accompanied by decreased BMD as in cardiovascular disease in KTrs.	27569941
Inflammation, osteoclast activating factor, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	POAF may represent a propensity for recurrent paroxysmal atrial fibrillation, and not simply a transient consequence of postoperative stress and inflammation.	27570120
Inflammation, Arthritis, Cerebrovascular accident	Altered Intercellular Communication	However, the least prevalent diseases were stroke (17.2%), joint inflammation (17.2%), and arthritis (9.0%).	27570449
Retinal Detachment, Inflammation	Altered Intercellular Communication	Clinical examination of the patient revealed anterior and posterior inflammation and bilateral serous retinal detachments.	27571426
Inflammation, Serous retinal detachment	Altered Intercellular Communication	Subsequent 6-month follow-up demonstrated complete resolution of the inflammation and bilateral serous detachments after completion of the prednisone taper over a 3-month period.	27571426
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	This form of autoimmune inflammation may occur after the recovery of T-cell activity within the donor graft targeting the host.	27571426
Inflammation, Sarcopenia	Altered Intercellular Communication	Serum markers of inflammation and oxidative stress in sarcopenia.	27571781
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Relationship of clinical symptoms with biomarkers of inflammation in pediatric inflammatory bowel disease.	27573259
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	In adult inflammatory bowel disease (IBD) patients, there is a strong discrepancy between symptoms and biomarkers of inflammation.	27573259
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Therefore, we aimed to investigate the relationship between clinical symptoms and biomarkers of inflammation in pediatric IBD.	27573259
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	There is a strong discrepancy between clinical symptoms and biomarkers of inflammation in children with IBD.	27573259
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	* A substantial proportion of asymptomatic pediatric inflammatory bowel disease (IBD) patients have elevated biomarkers of inflammation.	27573259
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	* There is a strong discrepancy between symptoms and biomarkers of inflammation in adults with IBD.	27573259
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	* Similarly to adult IBD patients, there is a strong discrepancy between clinical symptoms and biomarkers of inflammation in children with IBD.	27573259
Inflammation, Impaired T cell function, Intimal proliferation	Altered Intercellular Communication	PKCe mediates resistin-induced NADPH oxidase activation and inflammation leading to smooth muscle cell dysfunction and intimal hyperplasia.	27573736
Airway structure	Altered Intercellular Communication	BHR is mediated via airway smooth muscle tone and is modulated by the autonomic nervous system, nitric oxide, and airway inflammation.	27574738
Inflammation, Bronchopulmonary Dysplasia	Altered Intercellular Communication	No associations with systemic soluble markers of inflammation were observed for Met-BHR, birth, or BPD status.	27574738
Asthma	Altered Intercellular Communication	Airway neutrophilic inflammation is a pathological feature in some patients with severe asthma.	27574788
Inflammation	Altered Intercellular Communication	H pylori organisms were prospectively identified in 23 (7%) patients, all of whom had superficial dense lymphoplasmacytic inflammation expanding the lamina propria.	27574809
Hematoxylin and eosin stain method, Inflammation	Altered Intercellular Communication	One patient diagnosed as having normal gastric mucosa was retrospectively found to have inflammation with rare H pylori organisms originally overlooked on both H&E and Diff-Quik but later identified on immunostain (0.5%).	27574809
Inflammation, Gastritis	Altered Intercellular Communication	No patients with chemical gastritis (16%) or chronic inflammation (27%) were found to have H pylori.	27574809
Hematoxylin and eosin stain method, Inflammation	Altered Intercellular Communication	The organisms can be seen on routine H&E; when suspicious superficial or active inflammation is present without visible organisms, immunohistochemical stains will confirm presence or absence within a day.	27574809
Inflammation, Thrombosis, Cerebrovascular accident	Altered Intercellular Communication	Endothelial Function, Inflammation, Thrombosis, and Basal Ganglia Perivascular Spaces in Patients with Stroke.	27576214
ACSM3 gene, Inflammation, Neurologic Deficits	Altered Intercellular Communication	Dynamic changes in the levels of these cytokines may induce inflammation and may be closely associated with the development of delayed ischemic neurological deficits after SAH.	27576738
Inflammation, Appendicitis, CTCAE, Rupture	Altered Intercellular Communication	Appendicitis was defined as acute inflammation, rupture or abscess of the appendix on pathologic evaluation.	27577252
Acute Kidney Injury, CTCAE, Inflammation, Obesity	Altered Intercellular Communication	The Influence of Thyroid Function, Inflammation, and Obesity on Risk Prediction of Acute Kidney Injury by Cystatin C in the Emergency Department.	27578194
Inflammation, Obesity	Altered Intercellular Communication	Cystatin C (CysC), a newer renal biomarker, is influenced by thyroid function, inflammation and obesity.	27578194
Inflammation, Kidney Failure, Acute, Obesity	Altered Intercellular Communication	CysC is known to be influenced by thyroid function, inflammation and obesity, but in our large ED population there was no significant impact of these factors on the diagnostic accuracy of CysC to detect AKI in ED patients.	27578194
Inflammation, Myopathy, Myositis	Altered Intercellular Communication	Glucocorticoids (GCs), although effective at suppressing inflammation and inflammatory muscle loss, also cause myopathy with prolonged administration.	27578244
Inflammation, Tumor necrosis	Altered Intercellular Communication	The expression of 11b-HSD1 in response to proinflammatory stimuli was determined in a transgenic murine model of chronic inflammation (TNF-Tg) driven by overexpression of tumour necrosis factor (TNF)-a within tissues, including muscle.	27578244
Cachexia, Myositis	Altered Intercellular Communication	The contributions of 11b-HSD1 to muscle inflammation and wasting were assessed in vivo with the TNF-Tg mouse on an 11b-HSD1 null background.	27578244
Inflammation, Carcinogenesis, Neoplasms	Altered Intercellular Communication	TNFAIP8L2 (TIPE2 or tumor necrosis-alpha-induced protein-8 like 2) is a negative regulator for inflammation and an inhibitor for carcinogenesis.	27578327
Inflammation, Asthma	Altered Intercellular Communication	In 1042 subjects with refractory asthma recruited to the British Thoracic Society Severe Asthma Registry, we compared patient demographics, disease characteristics and biomarkers of inflammation in patients aged <65 years (n = 896) versus >=65 years (n = 146) and onset at age <18 years (n = 430) versus >=18 years (n = 526).	27578470
Shock, Inflammation, Sepsis	Altered Intercellular Communication	sST2 might have a role as a biomarker of shock or inflammation, but it cannot reflect echocardiographic findings of LV ejection fraction or diastolic filling in sepsis.	27578513
Inflammation	Altered Intercellular Communication	This may be related to increased uveoscleral outflow and intraocular inflammation after RRD, and it may be concluded that vitrectomy does not affect choroidal thickness.	27579730
Inflammation, Obesity	Altered Intercellular Communication	Angiogenesis in inflammation are hallmarks for adipose tissue expansion in obesity.	27581034
Proctitis	Altered Intercellular Communication	However, the effect of chronic EtOH consumption on CYP2E1, etheno-DNA adducts as well as anti-apoptotic proteins in the colorectal mucosa of heavy drinkers without colorectal inflammation is still not known.	27581253
Inflammation, Adenoma	Altered Intercellular Communication	The positive rates in conventional adenomas (24.0%, n = 146) and hyperplastic nodules (100%, n = 17) were each different from that found in inflammation (70.8%, n = 24), and spiral organisms were seen more frequently in the right-side large intestine than in the left (within mucus, 100%, n = 104 versus 95.0%, n = 119; within crypts, 65.4%, n = 104 versus 49.6%, n = 119).	27581381
Inflammation, hepcidin	Altered Intercellular Communication	Inflammation was present at delivery, which limited the utility of ferritin or hepcidin as iron-status indicators at delivery.	27581469
Inflammatory abnormality of the eye	Altered Intercellular Communication	Of 10 eyes, 5 showed moderate to severe ocular inflammation within a few days of injection.	27582674
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	This study demonstrates that linagliptin tends to improve endothelial and neurovascular microvascular function and is associated with decreased markers of inflammation in patients with type 2 diabetes.	27583476
Tip of appendix, Enterobiasis	Altered Intercellular Communication	Enterobius vermicularis infestation of the appendix can cause symptoms of appendiceal pain, independent of microscopic evidence of acute inflammation.	27585284
Inflammation, Appendicitis, CTCAE, Enterobiasis	Altered Intercellular Communication	We highlight that the symptoms of appendicitis can be due to Enterobius vermicularis infestation also without any histological evidence of acute inflammation.	27585284
Intraocular inflammation, Tularemia	Altered Intercellular Communication	In this paper, we report a case of intraocular inflammation during tularemia infection.	27585457
Communicable Diseases, Uveitis, Tularemia, Intraocular inflammation	Altered Intercellular Communication	Posterior uveitis may be an infrequent manifestation of tularemia infection, and therefore this infection should be considered in the differential diagnosis of intraocular inflammation in areas where F. tularensis is endemic.	27585457
Inflammation	Altered Intercellular Communication	Network analysis combined with a novel technique for biomarker computation allowed the identification of an alteration in aging-associated processes such as inflammation, oxidative stress and metabolic pathways, indicating that APOE4 possibly accelerates pathological processes physiologically induced by aging.	27585646
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	In conclusion, APOE4 role on inflammation and oxidation through the Notch signaling pathway could be crucial in elucidating the risk factors of Alzheimer's disease.	27585646
Inflammation, Hepatocarcinogenesis	Altered Intercellular Communication	Sympathetic nervous system promotes hepatocarcinogenesis by modulating inflammation through activation of alpha1-adrenergic receptors of Kupffer cells.	27585737
Inflammation, Liver carcinoma, FAM126A gene, Hyperactive behavior, Liver Cirrhosis	Altered Intercellular Communication	Hepatocellular carcinoma (HCC) frequently occurs in cirrhotic livers after chronic inflammation, and the SNS is hyperactive in advanced liver cirrhosis.	27585737
Hepatitis, Chronic, Hepatocarcinogenesis	Altered Intercellular Communication	However, it remains unclear whether the SNS promotes hepatocarcinogenesis by modulating chronic liver inflammation.	27585737
Degenerative polyarthritis, Inflammation, Atherosclerosis	Altered Intercellular Communication	Recent studies have reported that osteoarthritis (OA) is related to inflammation and atherosclerosis.	27585925
Inflammation, Infection	Altered Intercellular Communication	Increasing the ceftaroline fosamil dose beyond 600 mg every 12 h may provide additional benefit for patients with complicated skin and soft tissue infections (cSSTIs) with severe inflammation and/or reduced pathogen susceptibility.	27585969
Inflammation	Altered Intercellular Communication	This suggests that hBD-1 has a more constitutive role in host defense in the vocal cords, whereas hBD-2 expression may be a result of local inflammation or the presence of invading pathogens.	27586391
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Not only is depression associated with increased inflammation but inflammation is a risk factor for the genesis of depression.	27587328
Inflammation, Depression, CTCAE	Altered Intercellular Communication	ASPREE-D may not only define novel therapy but will provide mechanistic proof of concept of the role of inflammation in depression.	27587328
Tumor necrosis, Inflammation	Altered Intercellular Communication	M2BP abrogated the suppressive effects of APN on tumour necrosis factor (TNF)-a-induced inflammation in vascular endothelial cells.	27588936
Inflammation, Fracture, Hyperuricemia, Gout	Altered Intercellular Communication	This prospective study was undertaken to examine the relationship between gout, a disease characterized by hyperuricemia and inflammation, and risk of hip or wrist fracture in women.	27589491
Inflammation, Liver carcinoma, Communicable Diseases, Hepatitis B, Hepatitis C, FAM126A gene	Altered Intercellular Communication	Hepatocellular carcinoma (HCC) is associated with inflammation, and roughly 30 % of the global population shows serological evidence of current or past infection with hepatitis B or hepatitis C virus.	27589954
Inflammation, Leucocytic infiltrate	Altered Intercellular Communication	In mice with selective IL-6 ablation in monocytes/KCs, we observed decreased toxic liver injury, inflammatory infiltration, and systemic inflammation.	27589954
Pyelonephritis, Xanthogranulomatous, Inflammation, Fever, CTCAE	Altered Intercellular Communication	A 70-year-old male patient underwent left-sided nephrectomy for signs and symptoms that were suggestive of xanthogranulomatous pyelonephritis (recurrent fever, swollen malfunctioning kidney, granulomatous inflammation in renal biopsy).	27590254
Inflammation, Alkaptonuria	Altered Intercellular Communication	Comparative proteomics in alkaptonuria provides insights into inflammation and oxidative stress.	27590860
Inflammation, Rheumatism	Altered Intercellular Communication	Interesting similarities with proteomic studies on other rheumatic diseases were highlighted together with proteome alterations supporting the existence of oxidative stress and inflammation in AKU.	27590860
Inflammation	Altered Intercellular Communication	In contrast, the endogenous opioid system has an important analgesic action during chronic inflammation.	27590998
Inflammatory Bowel Diseases, Pain Distress Question, Inflammatory disorder	Altered Intercellular Communication	Psychological stress accompanies chronic inflammatory diseases such as IBD, and stress hormones can exacerbate pain signalling.	27590998
Inflammation, Fatigue	Altered Intercellular Communication	Systemic inflammation was not associated with perception of fatigue but surfactant protein D was connected to some dimensions of the impact of fatigue.	27591046
Crohns disease of the ileum", Inflammation, Ileitis	Altered Intercellular Communication	In summary, Crohn's disease ileitis is often associated with inflammation elsewhere in the gastrointestinal tract while non-specific ileitis was infrequently associated with inflammation elsewhere for both paediatric and adult patients.	27591764
Cholangitis, Primary Biliary Cholangitis	Altered Intercellular Communication	Hydrophobic bile acids suppress expression of AE2 in biliary epithelial cells and induce bile duct inflammation in primary biliary cholangitis.	27592379
Inflammation, Primary Biliary Cholangitis	Altered Intercellular Communication	Understanding the mechanisms of chronic inflammation in primary biliary cholangitis (PBC) is essential for successful treatment.	27592379
Inflammation, Thrombosis	Altered Intercellular Communication	Platelets are major players in haemostasis and thrombosis and are involved in inflammation.	27593518
Inflammation, Incontinence	Altered Intercellular Communication	Impact of Periurethral Inflammation on Continence Status Early After Robot-Assisted Radical Prostatectomy.	27597311
Bronchopulmonary Dysplasia, Pneumonitis, Hypertrophy	Altered Intercellular Communication	Heterozygous Crispld2+/- mice display features of BPD, including distal airspace enlargement, disruption of elastin, and neonatal lung inflammation.	27597766
Inflammation	Altered Intercellular Communication	RNA sequencing results from HLF-CRISPLD2(knockdown) suggest roles for CRISPLD2 in extracellular matrix and in inflammation.	27597766
Pneumonitis	Altered Intercellular Communication	Our data suggest that suppression of CRISPLD2 increases the risk of lung inflammation in early life and adulthood.	27597766
Inflammation, Demographics Domain, Diabetes Mellitus, Microcirculation disorders, Intestinal Motility	Altered Intercellular Communication	Clinical and experimental research has revealed that diabetes mellitus (DM) is characterized by intestinal hypomotility, gut microbial dysbiosis, increased gut permeability, microcirculation disorders, circulatory changes, and dysfunction of intestinal stem cells, which may be linked to inflammation of intestinal mucosa.	27598308
Inflammation, Appendicitis, CTCAE, Obstruction	Altered Intercellular Communication	Obstruction and inflammation of the appendix lumen is the leading physiopathological process during acute appendicitis (AA).	27598605
Inflammation, Congenital Abnormality	Altered Intercellular Communication	Several alternative reasons including congenital malformations and chronic inflammation have been identified as a cause of CAE.	27598894
Coronary artery ectasia, Inflammation	Altered Intercellular Communication	We also elucidate the recently proposed markers of chronic inflammation that might be associated with coronary artery ectasia.	27598894
Inflammation	Altered Intercellular Communication	Infiltration of inflammatory cells, most of which were lymphocytes, was also observed in the dermis and the epidermis in all cases, even though there were no clinical signs of inflammation.	27599121
Inflammation	Altered Intercellular Communication	Choroidal lesions were associated with clinical signs of inflammation, suggesting that they represent foci of disease activity.	27599125
Inflammation	Altered Intercellular Communication	Long-term barrier impairment might lead to chronic inflammation.	27599552
Inflammation, Atrophic nonunion of fracture	Altered Intercellular Communication	Biomarkers of inflammation and innate immunity in atrophic nonunion fracture.	27599571
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Many studies have found that systemic inflammation plays an important role in the pathogenesis of atrial fibrillation (AF).	27599578
palladium, Inflammation, Metabolic Syndrome X, MS gene	Altered Intercellular Communication	Low-grade chronic inflammation is present in patients on peritoneal dialysis (PD) and in metabolic syndrome (MS).	27600388
palladium, Inflammation, Metabolic Diseases	Altered Intercellular Communication	In patients on PD, inflammatory reaction is higher than in patients with MS. On the contrary, patients with MS have stronger oxidative stress response and adipose tissue activity caused probably by the chronic low level of inflammation and underlying metabolic disorders.	27600388
Inflammation, Obesity, Abdominal, Microalbuminuria, Hypertriglyceridemia, Endothelial dysfunction, Hypertension, CTCAE	Altered Intercellular Communication	Patients with MS had increased abdominal obesity, hypertension, hypertriglyceridemia, inflammation factors, IR, homocysteine and microalbuminuria as markers of endothelial dysfunction.	27600468
Infarction, Inflammation	Altered Intercellular Communication	Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue.	27600707
Presenile dementia, Inflammation	Altered Intercellular Communication	The study goal was to address the hypothesis that chronic inflammation may contribute to stroke-related dementia.	27600707
Inflammation, Renal Cell Carcinoma Pathway, Sarcopenia	Altered Intercellular Communication	Sarcopenia, or the degenerative loss of skeletal muscle mass, develops as a consequence of cancer-host interactions, including systemic inflammation and poor nutritional status, and is associated with a poor prognosis in patients with metastatic renal cell carcinoma (mRCC).	27601279
Communicable Diseases, Inflammation	Altered Intercellular Communication	During an infection or inflammation, several drug-metabolizing enzymes in the liver are down-regulated, including cytochrome P450 iso-enzymes.	27601292
Inflammation, Necrosis	Altered Intercellular Communication	Wound necrosis was distinctly associated with pathogenic fungal species, while taxa identified as allergenic filamentous fungi were associated with low levels of systemic inflammation.	27601572
Inflammation, Electrocardiogram: myocardial infarction (finding), Cardiac Death, Cerebrovascular accident	Altered Intercellular Communication	Gamma-glutamyl transferase (gamma-GT) is an enzyme present in the cell membranes, which is used as a new biomarker in prediction of inflammation, myocardial infarction, stroke, and cardiac death.	27601721
Inflammation	Altered Intercellular Communication	Our data suggest that the same dose of UV radiation induces significantly more inflammation in the morning than in the afternoon.	27602977
Communicable Diseases, pustule, Ki-1+ Anaplastic Large Cell Lymphoma	Altered Intercellular Communication	It is also important that clinicians recognize atypical clinical morphologies of cutaneous ALCL, including pustular lesions, which may masquerade as infectious or other inflammatory conditions, thereby delaying the onset of treatment.	27602978
Perifolliculitis	Altered Intercellular Communication	Recent surveys across the Solomon Islands indicated that whilst trachomatous inflammation-follicular (TF) was present at levels warranting intervention, the prevalence of trachomatous trichiasis (TT) was low.	27603015
Communicable Diseases, Tissue Factor	Altered Intercellular Communication	We observed a moderate prevalence of TF in children aged 1-9 years (n = 296/1135, 26.1%) but low prevalence of trachomatous inflammation-intense (TI) (n = 2/1135, 0.2%) and current Ct infection (n = 13/1002, 1.3%) in children aged 1-9 years, and TT in those aged 15+ years (n = 2/2061, 0.1%).	27603015
Inflammation, HIV-1 Infection Pathway	Altered Intercellular Communication	Oxidized lipoproteins are associated with markers of inflammation and immune activation in HIV-1 infection.	27603288
Inflammation	Altered Intercellular Communication	Surgical findings and pathologic results confirmed the diagnosis of small intestinal heterotopic pancreas with active chronic inflammation.	27603341
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Given both smoking and vitamin D are associated with coronary heart disease (CHD) via inflammation and smoking may interfere with the local antiinflammatory effects of vitamin D. We hypothesized that the relationship between smoking and severity of CHD may be modified by vitamin D.A cross-sectional study was conducted.	27603397
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Lifestyle, including dietary patterns, could involve specific factors participating in inflammation that confer a higher risk of suffering a stroke.	27603597
Inflammation	Altered Intercellular Communication	Increased 18F-FDG uptake was seen in the myocardial wall in three patients, indicating active inflammation.	27604109
Inflammation	Altered Intercellular Communication	Eventually, a facial skin biopsy was performed showing nonspecific chronic inflammation only.	27604462
Inflammation, Hematoma, Inguinal pain, Seroma, Testis	Altered Intercellular Communication	Secondary outcomes were short and long-term complications: hematoma and seroma formation, inflammation of the testis, chronic inguinal pain, reoperation, 30 days mortality.	27604667
Inflammation, Critical Illness, Liver Dysfunction, Hypoperfusion, Kidney Diseases	Altered Intercellular Communication	Herein, urinary neutrophil gelatinase-associated lipocalin (NGAL), L-type fatty acid-binding protein (L-FABP) and nonrenal disorders, including inflammation, hypoperfusion and liver dysfunction, were evaluated in 249 critically ill patients treated at our intensive care unit.	27605390
Inflammation, Heart failure	Altered Intercellular Communication	Salivary Biomarkers, Oral Inflammation, and Functional Status in Patients With Heart Failure.	27605566
Immunologic Deficiency Syndromes, Inflammation, Sinusitis, Malignant Head and Neck Neoplasm	Altered Intercellular Communication	Chronic sinusitis may be involved in the etiology of certain head and neck cancers (HNCs), due to immunodeficiency or inflammation.	27606895
Inflammation	Altered Intercellular Communication	Clearance of autophagy-associated dying retinal pigment epithelial cells - a possible source for inflammation in age-related macular degeneration.	27607582
Cessation of life, Inflammation, methyldopa	Altered Intercellular Communication	Our data suggest that cells undergoing autophagy-associated cell death engage in clearance mechanisms guided by professional and non-professional phagocytes, which is accompanied by inflammation as part of an in vitro modeling of AMD pathogenesis.	27607582
Lichen Planus, Inflammation, Dyslipidemias	Altered Intercellular Communication	Epicardial fat tissue thickness is increased in patients with lichen planus and is linked to inflammation and dyslipidemia.	27609552
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a major role in the progression of atherosclerosis.	27609552
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Sitting time was positively associated with the prevalence of NAFLD, and this association might be affected by inflammation.	27609847
CLU protein, human	Altered Intercellular Communication	Compared to IC, CLI is a systemic inflammatory condition, which may explain the extremely poor outcome associated with it.	27611073
Respiratory Distress Syndrome, Adult, Inflammation	Altered Intercellular Communication	To assess whether sevoflurane would improve gas exchange and inflammation in ARDS.	27611637
Inflammation, COL4A2 wt Allele	Altered Intercellular Communication	Herby we assessed the relevance of systemic inflammation in patients suffering ICH.	27611984
Granulomatous Mastitis, Primary malignant neoplasm, Immunoglobulin M	Altered Intercellular Communication	Idiopathic granulomatous mastitis (IGM) is a chronic inflammatory condition that is confused with cancer.	27612044
ARCN1 gene, Inflammation	Altered Intercellular Communication	Susceptibility for cigarette smoke-induced DAMP release and DAMP-induced inflammation in COPD.	27612964
ARCN1 gene, Inflammation, Moist	Altered Intercellular Communication	We investigated whether CS-induced damage-associated molecular pattern (DAMP) release or DAMP-mediated inflammation contributes to susceptibility for COPD.	27612964
Airway structure	Altered Intercellular Communication	LL-37 and mtDAMPs induced neutrophilic airway inflammation, exclusively in mice susceptible for CS-induced airway inflammation.	27612964
ARCN1 gene, Inflammation	Altered Intercellular Communication	Furthermore, our studies indicate that a predisposition to release DAMPs and subsequent induction of inflammation may contribute to the development of COPD.	27612964
Inflammation	Altered Intercellular Communication	To examine whether patients with a mature normal pouch [> 1 year post ileostomy closure] have microbial stool characteristics that can predict pouch inflammation.	27613294
Inflammation, Exanthema, Skin irritation	Altered Intercellular Communication	Moulded orthoses can have defects after manufacturing that can lead to localised skin irritation, inflammation and subsequent rash formation.	27613591
Inflammation, Liver carcinoma	Altered Intercellular Communication	Immune inflammation indicators and implication for immune modulation strategies in advanced hepatocellular carcinoma patients receiving sorafenib.	27613839
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation that leads to excessive remodeling of the lung extracellular matrix (ECM), resulting in release of protein fragments (neo-epitopes) to the blood.	27614218
Perforation (observation), Necrosis, Infertility, Stenosis Morphology, Pelvic Inflammatory Disease	Altered Intercellular Communication	Early removal of foreign objects prevents ulceration, necrosis, stenosis, perforations, and late serious sequelae such as pelvic inflammation and infertility.	27614288
Inflammation, Hypercholesterolemia, atherosclerotic	Altered Intercellular Communication	Background Inflammation and hypercholesterolaemia contribute to atherosclerotic changes which can start in childhood.	27614353
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation associated with recurrence and poor prognosis in numerous cancer types.	27614622
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	This brain-spleen cell cycling after stroke affects systemic inflammation and the brain inflammatory milieu and may be a target for emerging therapeutic studies.	27615448
Glomerulonephritis, Glomerular capillaries structure	Altered Intercellular Communication	Glomerular endocapillary inflammation may result in crescent formation and exuded protein leakage, which may induce TII in antineutrophil cytoplasmic antibody-associated glomerulonephritis (ANCAGN).	27616759
Inflammation	Altered Intercellular Communication	Sterile inflammation leads to the formation of ANCA-mediated neutrophil extracellular traps (NETs), which may stimulate macrophages and dendritic cells via TLR4 and induce NF-kB-dependent mRNA expression and translation of pro-IL-1b.	27616759
Inflammation	Altered Intercellular Communication	Sterile inflammation utilizing the NLRP3 inflammasome might be a characteristic reaction limited to the tubulointerstitium.	27616759
Inflammation, Fever, CTCAE	Altered Intercellular Communication	The diagnostic strategy in patients with fever or inflammation of unknown origin remains a major clinical challenge.	27617327
Inflammation	Altered Intercellular Communication	18F-FDG-PET/CT is a useful method in the diagnostic workup of patients with inflammation of unknown origin.	27617327
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Regarding 18F-FDG-PET/CT-imaging inflammation of unknown origin and unexplained fever can be joined to one entity.	27617327
Necrotizing granulomatous inflammation, Fat necrosis, Fibrosis Assessment	Altered Intercellular Communication	Biopsy demonstrated focal lobular and septal granulomatous inflammation admixed with septal fibrosis and lobular lymphohistiocytic infiltrate associated with fat necrosis.	27617607
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Neutrophil extracellular traps (NETs) are found to trigger inflammation and coagulation.	27617671
Inflammation, vinyltriethoxysilane	Altered Intercellular Communication	The NETs formation correlated positively with the VTE risk, rather than the parameters of inflammation or disease severity.	27617671
Sepsis, Inflammation, vinyltriethoxysilane	Altered Intercellular Communication	The systemic inflammation during sepsis primes neutrophils to release NETs with increased risk of VTE.	27617671
Orchitis, Diverticulosis, Diverticular Diseases	Altered Intercellular Communication	Diverticular inflammation and complication assessment (DICA) endoscopic classification has been recently developed for patients suffering from diverticulosis and diverticular disease.	27622352
Inflammation, Diverticular Diseases	Altered Intercellular Communication	Also, the criteria for symptomatic uncomplicated diverticular disease in the absence of macroscopic inflammation are not clearly defined.	27622376
Inflammation	Altered Intercellular Communication	Musculoskeletal ultrasound: an effective tool to help medical students improve joint inflammation detection?	27622404
Inflammation	Altered Intercellular Communication	MSUS may be an effective technique for helping students to acquire the ability to detect joint inflammation.	27622404
Gingivitis, Periodontitis, Bacteremia, Diabetes Mellitus	Altered Intercellular Communication	This would be the case of patients with diabetes mellitus and periodontitis, who exhibit exacerbated gingival inflammation and may be more prone to developing oral-derived bacteremia.	27622449
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC), a chronic inflammation of the colon, is often more severe in children than adults.	27622899
Inflammation	Altered Intercellular Communication	These data suggest a function for NK cells in the pathogenesis and/or modulation of inflammation in GPA.	27624647
Arthritis, Inflammatory abnormality of the eye, Fever, CTCAE	Altered Intercellular Communication	Interestingly, the ocular inflammation resolved completely following therapeutic vitrectomy in both eyes whereas the systemic symptoms of fever and arthritis continued to wax and wane while on treatment with oral methotrexate and corticosteroids.	27625029
Inflammation, Pre-Eclampsia	Altered Intercellular Communication	Preeclampsia reflects an unusual increase in systemic inflammation during pregnancy.	27626972
Communicable Diseases, Inflammation	Altered Intercellular Communication	Treatment of the cells with antioxidant agents just after infection completely abolished TNF secretion, indicating an involvement of ROS in inflammation induced during MAYV infection.	27627069
Inflammation, Obesity	Altered Intercellular Communication	Alterations in endocrine functions and low-grade systemic inflammation represent fundamental characteristics of obesity.	27627133
Fatigue	Altered Intercellular Communication	The possibility that inflammation-induced alterations in tryptophan metabolism relates to specific dimensions of fatigue was also investigated in a subsample of patients.	27627133
Refractory anemias, Inflammation, Rheumatoid Arthritis, Infiltration	Altered Intercellular Communication	Multiple lymphocyte subsets like T and B cells have been connected to joint infiltration and inflammation in rheumatoid arthritis (RA).	27629388
Weight decreased, Gastrointestinal inflammation	Altered Intercellular Communication	Ingestion of 2'-FL by mice reduced C. jejuni colonization by 80%, weight loss by 5%, histologic features of intestinal inflammation by 50-70%, and induction of inflammatory signaling molecules of the acute-phase mucosal immune response by 50-60% (P < 0.05).	27629573
Weight decreased, Gastrointestinal inflammation	Altered Intercellular Communication	Ingestion of 2'-FL by mice reduced C. jejuni colonization by 80%, weight loss by 5%, histologic features of intestinal inflammation by 50-70%, and induction of inflammatory signaling molecules of the acute-phase mucosal immune response by 50-60% (P < 0.05).	27629573
Inflammation, Fibrosis Assessment, Heart failure	Altered Intercellular Communication	Galectin-3 (Gal-3) as a biomarker of fibrosis and inflammation has been implicated in the development and progression of heart failure (HF) and may predict increased morbidity and mortality in society.	27629834
Inflammation, Hemorrhage, Structure of porta hepatis, Neoplasms, Aneurysm	Altered Intercellular Communication	A 66-year-old man, with an abnormal porta hepatis, consistent with tumor or inflammation, developed massive bleeding from one of numerous hepatic artery aneurysms, and coil embolization achieved control of bleeding.	27630223
Inflammation, Liver carcinoma, Hepatitis C	Altered Intercellular Communication	The study population was 82 adult Japanese patients who had chronic inflammation due to HCV infection diagnosed by pathological examination of liver biopsy specimens, including 21 patients with early hepatocellular carcinoma (eHCC) and HCV-related LC.	27630292
Gallbladder Carcinoma	Altered Intercellular Communication	Preoperative Systemic Inflammation and Complications Affect Long-term Gallbladder Carcinoma Outcomes Following Surgery with Curative Intent.	27630345
Inflammation, Prostatic Intraepithelial Neoplasias, Hyperplasia, Prostate carcinoma	Altered Intercellular Communication	Patients were stratified by final pathology reports of RARP specimens: Group I: Prostate cancer, N=22 (40%); group II: abnormal (prostate intraepithelial neoplasia; atypical small acinar proliferation), N=18 (32.7%); and group III: benign (nodular hyperplasia or inflammation), N=15 (27.3%).	27630346
Inflammation, Bipolar Disorder, Cardiovascular Diseases	Altered Intercellular Communication	Low vitamin D and depressive symptoms are associated with inflammation activation that predicts cardiovascular disease.	27631120
Hepatic inflammation, Complete atrioventricular block, Hepatitis B, fibrogenesis	Altered Intercellular Communication	The mechanisms underlying hepatic inflammation and fibrogenesis in chronic hepatitis B (CHB) are complex and several cytokines are involved.	27631226
Temporomandibular Joint Disorders, Pain Distress Question, Inflammation	Altered Intercellular Communication	In the eyes with presumed TMD, patients denied pain or inflammation.	27631347
Inflammation, Hyperemia, Pain Distress Question	Altered Intercellular Communication	In the 4 patients with a clinical history of inflammation (bulbar hyperemia and pain), and in the 1 patient with active inflammation at the time of HR-OCT imaging, HR-OCT also demonstrated thinning with an intact epithelium.	27631347
Temporomandibular Joint Disorders, Inflammation	Altered Intercellular Communication	In contrast to the TMD group, in the group with signs of inflammation, a dense hyperreflective band was noted in the stroma directly below the epithelium in the area of thinning, suggestive of scarring and/or cellular infiltration.	27631347
Inflammation, Fibrosis Assessment, Hemorrhage	Altered Intercellular Communication	We interpreted these displaced small nests to be the result of mechanical implantation occurring during the ureteroscopic procedure on the basis of the finding of associated linear fibrosis, inflammation, hemorrhage, and foreign body giant cells.	27631511
Inflammation	Altered Intercellular Communication	Apart from individual effects of structural damage or inflammation, genetic factors are suggested to influence HP.	27631659
Communicable Diseases	Altered Intercellular Communication	Inflammation-related anorexic response has been observed in systemic diseases as well as in localized infection and is an important issue in patient care.	27631979
Myeloid	Altered Intercellular Communication	We show that in infected mice, splenic extramedullary erythropoiesis could compensate for the chronic low-grade type I inflammation-induced phagocytosis of senescent red blood cells (RBCs) in spleen and liver myeloid cells, as well as for the impaired maturation of RBCs occurring in the bone marrow and spleen.	27632207
Inflammation, Liver damage, Hypoxia	Altered Intercellular Communication	In the intratracheal lipopolysaccharide model, 1,500 IU of intraperitoneal cholecalciferol treatment 6 hours postinjury reduced alveolar inflammation, cellular damage, and hypoxia.	27632669
Sepsis	Altered Intercellular Communication	Sepsis Pathophysiology, Chronic Critical Illness, and Persistent Inflammation-Immunosuppression and Catabolism Syndrome.	27632674
Sepsis	Altered Intercellular Communication	Once thought to be predominantly a syndrome of over exuberant inflammation, sepsis is now recognized as a syndrome of aberrant host protective immunity.	27632674
Inflammation	Altered Intercellular Communication	Patients with chronic critical illness often exhibit "a persistent inflammation-immunosuppression and catabolism syndrome," and it is proposed here that this state of persisting inflammation, immunosuppression and catabolism contributes to many of these adverse clinical outcomes.	27632674
septic	Altered Intercellular Communication	Although newer therapeutic interventions are targeting the inflammatory, the immunosuppressive, and the protein catabolic responses individually, successful treatment of the septic patient with chronic critical illness and persistent inflammation-immunosuppression and catabolism syndrome may require a more complementary approach.	27632674
Inflammation	Altered Intercellular Communication	The physical stress placed on the tendon results in microtrauma, which leads to subsequent inflammation and degeneration.	27632817
Inflammation, Corneal Endothelial Cell Loss	Altered Intercellular Communication	Markers of endothelial damage, inflammation, and cellular aging were completely attenuated by red wine consumption.	27633722
Inflammation, Corneal Endothelial Cell Loss	Altered Intercellular Communication	Cigarette smoke results in acute endothelial damage, vascular and systemic inflammation, and indicators of the cellular aging processes in otherwise healthy nonsmokers.	27633722
Inflammation	Altered Intercellular Communication	Periostin, an extracellular matrix protein produced by fibroblasts, induces chronic inflammation by stimulating TSLP production.	27634769
Inflammation	Altered Intercellular Communication	No participants had clinical evidence of joint inflammation at the time of scanning.	27635596
Inflammation, Hyperuricemia	Altered Intercellular Communication	Although individuals with asymptomatic hyperuricemia lack ultrasound features of inflammation or structural joint changes, they demonstrate a similar frequency of urate deposition.	27635596
Inflammation	Altered Intercellular Communication	Poor psychological well-being and increased serum cytokine levels, but not colonic low-grade inflammation, were associated with IBS-like symptoms.	27636379
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Inflammatory bowel disease (IBD) is characterized by a chronic inflammation of the gut, partly driven by defects in the expression and function of pattern recognition receptors, including the IFI16 protein.	27636380
Data types - Address, physiopathological	Altered Intercellular Communication	We hypothesize that such changes may result in disturbed cellular clearance and a perturbed cell-to-cell communication that may contribute to neuronal dysfunction and cell death in AD.	27636840
Inflammation, Malignant neoplasm of gastrointestinal tract, Neoplasms	Altered Intercellular Communication	Several NADPH oxidase family members, including dual oxidase 2 [DUOX2], are expressed in human tumors, particularly gastrointestinal cancers associated with long-standing chronic inflammation.	27637085
Cessation of life, Sepsis, Multiple Organ Failure, Inflammation	Altered Intercellular Communication	Death from sepsis in the intensive therapy unit (ITU) is frequently preceded by the development of multiple organ failure as a result of uncontrolled inflammation.	27637335
Inflammation, Cartilage damage, BDI - Functional Impairment, Erosion of bone, Arthritis	Altered Intercellular Communication	Cartilage damage and bone erosion are more prominent determinants of functional impairment in longstanding experimental arthritis than synovial inflammation.	27638666
Inflammation, Joints, Refractory anemias, Rheumatoid Arthritis, BDI - Functional Impairment	Altered Intercellular Communication	Chronic inflammation of articular joints causing bone and cartilage destruction consequently leads to functional impairment or loss of mobility in affected joints from individuals affected by rheumatoid arthritis (RA).	27638666
Inflammation, Cartilage damage, Refractory anemias, Tumor necrosis, BDI - Functional Impairment, Acute and chronic inflammation, Erosion of bone	Altered Intercellular Communication	In this context, we investigated the impact of the distinct components, including synovial inflammation, bone erosion or cartilage damage, as well as the effect of blocking tumor necrosis factor (TNF) on functional impairment in human-TNF transgenic (hTNFtg) mice, a chronic inflammatory erosive animal model of RA.	27638666
Erosion lesion, Cartilage damage, Synovitis	Altered Intercellular Communication	By investigating the association of gait parameters with inflammation-mediated joint pathologies at different time points of the disease course, we found a relationship between gait parameters and the extent of cartilage damage and bone erosions, but not with the extent of synovitis in this chronic model.	27638666
Inflammation	Altered Intercellular Communication	However, blocking TNF did not restore full functionality owing to remaining subclinical inflammation and structural microdamage.	27638666
Inflammation, Cartilage damage, BDI - Functional Impairment, Erosion of bone, Arthritis	Altered Intercellular Communication	Our findings indicate that cartilage damage and bone erosion, but not synovial inflammation, are the most important determinants for progressive functional impairment in this chronic erosive arthritis model.	27638666
Inflammation	Altered Intercellular Communication	Recent longitudinal work suggests that weight change is an important risk factor for inflammation across the full range of BMI.	27638785
Weight Gain, Inflammation	Altered Intercellular Communication	However, few studies have examined whether the risk of inflammation differs by patterns of weight gain over time.	27638785
Weight Gain, Inflammation, Metabolic Diseases	Altered Intercellular Communication	These results suggest that trajectories of weight gain are an important clinical concern and may identify those at risk for inflammation and the development of cardiometabolic disease.	27638785
Inflammation	Altered Intercellular Communication	18F-FDG positron emission tomography (PET) can identify plaque inflammation as a surrogate endpoint for vascular interventional drug trials.	27639759
Coronary Arteriosclerosis	Altered Intercellular Communication	(Vascular Inflammation in Patients at Risk for Atherosclerotic Disease; NTR5006).	27639759
Dysplasia, Gastrointestinal inflammation	Altered Intercellular Communication	Fx-/- mice receiving control bone marrow cells had intestinal inflammation and dysplasia, and reduced expression of cytokines produced by cytotoxic T cells.	27639802
Colitis	Altered Intercellular Communication	Mini-endoscopic images revealed that hgd40 and anti-TNF reduced colon inflammation over 3 days; hgd40 reduced colitis in TNFR double-knockout mice.	27639807
Inflammation, Aortic Valve Stenosis	Altered Intercellular Communication	Aortic valve stenosis is characterized by inflammation and extracellular matrix remodelling.	27643581
Inflammation, Prostate carcinoma, Benign prostatic hypertrophy, Structure of posterior cerebral artery	Altered Intercellular Communication	The human papilloma viruses (HPVs) are a family of sexually transmitted viruses which have may have roles in the etiology of inflammation in the prostate leading to benign prostatic hyperplasia (BPH) and prostate cancer (PCa).	27644644
Cessation of life, Communicable Diseases, Inflammation	Altered Intercellular Communication	We identified numerous proteins that provide evidence of activation of the innate immunity system in two of the mummies, one of which also contained proteins indicating severe tissue inflammation, possibly indicative of an infection that we can speculate may have been related to the cause of death.This article is part of the themed issue 'Quantitative mass spectrometry'.	27644972
Inflammation, Autoimmune Disorder, CTCAE	Altered Intercellular Communication	Multiple Sclerosis (MS) is an autoimmune disorder leading to central nervous system inflammation.	27645349
Autoimmune Diseases, Sarcoidosis, Myelitis, Lupus Erythematosus	Altered Intercellular Communication	According to the new extended definition, NMOSD is closely associated with extensive spinal cord inflammation occurring in the course of systemic autoimmune diseases as sarcoidosis or lupus erythematodes.	27645353
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	A subset of patients with inflammatory bowel diseases (IBD) have continuously active inflammation, leading to a high number of complications and high direct health care costs (diagnostic tests, medications, and surgeries) and indirect costs (reduced employment and productivity and fewer opportunities for activities).	27645518
Inflammation, Malnutrition, Chronic Kidney Diseases	Altered Intercellular Communication	Associations among Serum Beta 2 Microglobulin, Malnutrition, Inflammation, and Advanced Cardiovascular Event in Patients with Chronic Kidney Disease.	27645611
Inflammation, Malnutrition, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	This study examines the associations among serum b2 microglobulin (B2M), malnutrition, inflammation, and atherosclerosis (MIA) in those with chronic kidney disease (CKD).	27645611
Inflammation, Neuralgia, Pain Distress Question	Altered Intercellular Communication	Recent data provided proof that neuropathic pain patients exhibit increased numbers of immunosuppressive regulatory T cells (Tregs), which may represent an endogenous attempt to limit inflammation and to reduce pain levels.	27646435
Inflammation, Neuralgia	Altered Intercellular Communication	Our findings suggest that in neuropathic pain, enhanced targeting of SIRT1 by miR-124a and miR-155 induces a bias of CD4(+) T cell differentiation towards Tregs, thereby limiting pain-evoking inflammation.	27646435
Carcinoma of lung	Altered Intercellular Communication	Significance of coexistent granulomatous inflammation and lung cancer.	27646525
Granulomatous inflammation	Altered Intercellular Communication	Coexistence of lung cancer and granulomatous inflammation in the same patient confuses clinicians.	27646525
Necrotizing granulomatous inflammation, Primary malignant neoplasm	Altered Intercellular Communication	One hundred and twenty-seven patients underwent lung resection for cancer, out of which 19 (14.9%) had coexistent granulomatous inflammation in the resected specimen.	27646525
Granulomatous inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Incidental detection of granulomatous inflammation in patients undergoing lung resection for cancer, even in a TB-endemic country, may not require any intervention.	27646525
Airway structure, Sleep-Disordered Breathing, Signs and Symptoms, Respiratory	Altered Intercellular Communication	We aimed to investigate the association between nGER and respiratory symptoms, exacerbations of respiratory symptoms, SDB and airway inflammation.	27646537
Inflammation	Altered Intercellular Communication	In patients with NMIBC, markers of systemic inflammation response are associated with disease recurrence and progression.	27646875
Inflammation, Pain Distress Question	Altered Intercellular Communication	SPECT-CT showed increased radiotracer uptake and inflammation at the level of pain generation indicated by history and physical examination.	27647036
Intraocular inflammation, Endophthalmitis, CTCAE, Traumatic injury	Altered Intercellular Communication	Endophthalmitis is potentially devastating intraocular inflammation following eye trauma or surgery.	27647122
Diabetic Nephropathy, Inflammation	Altered Intercellular Communication	The effects of selenium supplementation on biomarkers of inflammation and oxidative stress in patients with diabetic nephropathy: a randomised, double-blind, placebo-controlled trial.	27647263
Inflammation	Altered Intercellular Communication	Osteopontin (OPN) is an essential cytokine involved in immune cell recruitment and an important regulator of inflammation.	27647996
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Backgroud: Increasing evidence suggests the involvement of chronic inflammation in the progression of prostate cancer, and prostaglandin-endoperoxide synthase 2 (PTGS2), also known as cyclooxygenase-2, catalyzes the rate-limiting steps of the pathway.	27647999
Inflammation, Calcification of coronary artery, Rheumatoid Arthritis	Altered Intercellular Communication	Coronary Artery Calcification Is Related to Inflammation in Rheumatoid Arthritis: A Long-Term Follow-Up Study.	27648442
Refractory anemias, Inflammation, SLC25A20 gene	Altered Intercellular Communication	CAC is related to inflammation in patients with RA.	27648442
Communicable Diseases, Inflammation	Altered Intercellular Communication	Distinction between inflammation secondary to surgery, especially coronary artery bypass graft with cardiopulmonary bypass (CPB), and inflammation due to infection is difficult in surgical intensive care unit (ICU) patients.	27648690
Communicable Diseases, Inflammation	Altered Intercellular Communication	In conclusion, CD64 index only in combination with CRP concentrations could be used to discriminate inflammation due to surgery from that due to infection in this particular population.	27648690
Inflammation, Lymphoma	Altered Intercellular Communication	Lymphoma and inflammation in the orbit: Diagnostic performance with diffusion-weighted imaging and dynamic contrast-enhanced MRI.	27649521
Orbital lymphoma, Orbital Pseudotumor	Altered Intercellular Communication	Parameters of DWI and DCE MRI were evaluated in these 30 patients with orbital lymphoma and 23 patients with orbital inflammation.	27649521
Orbital lymphoma, Orbital Pseudotumor	Altered Intercellular Communication	The combination of both was significantly superior to DWI for differentiation of orbital lymphoma from orbital inflammation (P = 0.016 for reviewer 1; P = 0.001 for reviewer 2).	27649521
Inflammation, Lymphoma	Altered Intercellular Communication	The combination of DWI and DCE MRI can improve diagnostic performance in differentiating lymphoma from inflammation in the orbit compared with DWI alone.	27649521
Inflammation, Atrophic, Adenocarcinoma of prostate	Altered Intercellular Communication	Inflammation and focal atrophy in prostate needle biopsy cores and association to prostatic adenocarcinoma.	27649956
Proliferative Inflammatory Atrophy, Inflammation, Traumatic injury, Adenocarcinoma of prostate	Altered Intercellular Communication	The possible origin of proliferative inflammatory atrophy in the regenerative proliferation of prostate epithelial cells in response to injury caused by inflammation, and their relation to prostate adenocarcinoma have not been defined.	27649956
Inflammation, Atrophic	Altered Intercellular Communication	Inflammation and focal atrophy are common pathological findings in prostate biopsies, currently not routinely included in surgical pathology reports.	27649956
Inflammation, Focal atrophy, Adenocarcinoma, Malignant Neoplasms, Intraepithelial Neoplasia	Altered Intercellular Communication	Prostate needle biopsies from 203 patients with clinical parameters suspicious for malignancy were evaluated for the presence and extent of chronic inflammation, type and grade of focal atrophy, high-grade intraepithelial neoplasia, and adenocarcinoma.	27649956
Adenocarcinoma, Inflammation	Altered Intercellular Communication	Chronic inflammation was observed in 77.3% of the biopsies, significantly associated to adenocarcinoma (P = .031).	27649956
Inflammation, Adenocarcinoma of prostate	Altered Intercellular Communication	Moderate/severe inflammation in at least 1 biopsy core increased the risk of prostate adenocarcinoma (odds ratio, 2.94; 95% confidence interval, 1.27-6.8), whereas glandular localization of inflammation decreased the risk.	27649956
Proliferative Inflammatory Atrophy, Inflammation, Atrophic	Altered Intercellular Communication	Focal atrophy was present in 72.9% of the biopsies, proliferative inflammatory atrophy was the most common type, and its grade was significantly associated to inflammation (P < .0001) and inflammation intensity (P = .003).	27649956
Adenocarcinoma of prostate, Inflammation	Altered Intercellular Communication	An association between prostate adenocarcinoma and inflammation was found, with higher odds in presence of moderate/severe inflammation in at least 1 biopsy core.	27649956
Proliferative Inflammatory Atrophy, Inflammation	Altered Intercellular Communication	Increasing grades of proliferative inflammatory atrophy were associated to high levels of inflammation, supporting its previously proposed inflammatory nature.	27649956
Chronic Infantile Neurological, Cutaneous, and Articular Syndrome, NLRP3 gene, Chronic Urticaria	Altered Intercellular Communication	This is despite almost all MWS patients having family members with similar symptoms and children with NOMID presenting with chronic infantile urticaria associated with multi-system inflammation.	27650144
Chronic Infantile Neurological, Cutaneous, and Articular Syndrome, Familial cold urticaria, NLRP3 gene, Muckle-Wells Syndrome	Altered Intercellular Communication	Cryopyrin-associated periodic syndromes (CAPS) encapsulate three auto-inflammatory conditions, ranging in severity from mild (familial cold auto-inflammatory syndrome: FCAS), moderate (Muckle-Wells syndrome: MWS) and severe (neonatal onset multi-inflammatory disorder: NOMID).	27650144
Atherosclerosis of renal artery, HLA Class IA Histocompatibility Antigen Measurement, Cerebrovascular accident	Altered Intercellular Communication	Inflammation comprises important aspects of large-artery atherosclerosis (LAA) stroke pathophysiology.	27650381
Inflammation, Aortic Aneurysm, Abdominal	Altered Intercellular Communication	Age-Associated Sirtuin 1 Reduction in Vascular Smooth Muscle Links Vascular Senescence and Inflammation to Abdominal Aortic Aneurysm.	27650558
Old age, Inflammation	Altered Intercellular Communication	In this study, we investigated the role of SIRT1 (Sirtuin 1), a class III histone deacetylase, in AAA formation and the underlying mechanisms linking vascular senescence and inflammation.	27650558
vascular inflammations	Altered Intercellular Communication	Mechanistically, the reduction of SIRT1 was shown to increase vascular cell senescence and upregulate p21 expression, as well as enhance vascular inflammation.	27650558
Inflammation, Glucocorticoid deficiency with achalasia, Muscle, Smooth, Vascular	Altered Intercellular Communication	These findings provide evidence that SIRT1 reduction links vascular senescence and inflammation to AAAs and that SIRT1 in vascular smooth muscle cells provides a therapeutic target for the prevention of AAA formation.	27650558
Pancreatic carcinoma	Altered Intercellular Communication	Prognostic Value of the CRP/Alb Ratio, a Novel Inflammation-Based Score in Pancreatic Cancer.	27650825
Primary malignant neoplasm	Altered Intercellular Communication	However, as an inflammation-based score, its prognostic value for cancer has scarcely been investigated.	27650825
Inflammation, Dental Plaque	Altered Intercellular Communication	Repeated carotid measurements showed that inflammation was involved in novel plaque formation, while HDL-C was protective.	27650831
Hypertension, CTCAE	Altered Intercellular Communication	In addition, it was demonstrated in animal models that TREGs may prevent angiotensin II-induced hypertension and vascular injury/inflammation.	27653031
Laryngitis	Altered Intercellular Communication	Our findings indicate that laryngeal inflammation is not directly mediated by loss of Treg cells in response to smoking and reflux in local tissue and increased ImmunoCRIT values in smokers implicate a role for this environmental exposure in modulating laryngeal immune homeostasis.	27653511
Pneumonitis	Altered Intercellular Communication	Atherogenic high cholesterol/high fat diet induces TLRs-associated pulmonary inflammation in C57BL/6J mice.	27653962
Hypercholesterolemia, Pneumonitis	Altered Intercellular Communication	These findings suggested that high cholesterol/high fat diet-induced hypercholesterolemia could result in TLRs/NFkB pathway-associated low-grade pulmonary inflammation in C57BL/6J mice, which might alter the lung's immune responsiveness to a variety of environmental exposures.	27653962
Acute inflammation	Altered Intercellular Communication	Comparison of the safety and efficacy of single injection of subtenon triamcinolone and topical dexamethasone in reducing postoperative inflammation after phacoemulsification and intraocular lens implantation.	27654733
Inflammation, Folliculitis	Altered Intercellular Communication	Folliculitis is defined as the inflammation of the follicles.	27655127
Inflammation, Malnutrition	Altered Intercellular Communication	Mortality in children with complicated severe acute malnutrition is related to intestinal and systemic inflammation: an observational cohort study.	27655441
Diarrhea, Gastrointestinal inflammation	Altered Intercellular Communication	We investigated diarrhea, enteropathogens, and systemic and intestinal inflammation for their interrelation and their associations with mortality in children with SAM.	27655441
Cessation of life, Inflammation, Diarrhea	Altered Intercellular Communication	Mortality was directly related to high systemic inflammation (path coefficient = 0.49), whereas diarrhea, high calprotectin, and low SCFA production related to death indirectly via their more direct association with systemic inflammation.	27655441
Inflammation, Diarrhea, Gastrointestinal inflammation	Altered Intercellular Communication	Diarrhea, high intestinal inflammation, low concentrations of fecal SCFAs, and high systemic inflammation are significantly related to mortality in SAM.	27655441
Inflammation, Blood Clot, Kidney Failure, Acute	Altered Intercellular Communication	Excessive platelet activation contributes to AKI through the formation of microthrombi and amplification of systemic inflammation.	27656709
Airway structure	Altered Intercellular Communication	However, the two groups did not differ in airway inflammation, which indicated that a synergistic effect of the LABA on enhancing the anti-inflammatory action of the ICS was not clinically apparent.	27657522
Inflammation, Airway structure, Smoking, Obstruction, Obesity	Altered Intercellular Communication	Smoking, obesity, physical inactivity, airway inflammation and obstruction, and adipose tissue and inflammatory marker activation are related in systemic inflammation.	27658459
Inflammation, Schizophrenia	Altered Intercellular Communication	Low-grade inflammation is also associated with schizophrenia.	27658459
Inflammation, Schizophrenia	Altered Intercellular Communication	Resistin is a biomarker of systemic inflammation associated with smoking among patients with schizophrenia on clozapine treatment.	27658459
Inflammation, Impaired cognition	Altered Intercellular Communication	Body mass and cognitive decline are indirectly associated via inflammation among aging adults.	27658542
Inflammation, Impaired cognition, Nerve Degeneration	Altered Intercellular Communication	Inflammatory models of neurodegeneration suggest that higher circulating levels of inflammation can lead to cognitive decline.	27658542
Inflammation, Impaired cognition	Altered Intercellular Communication	Despite established independent associations between greater body mass, increased inflammation, and cognitive decline, no prior research has explored whether markers of systemic inflammation might mediate the association between body mass and changes in cognitive functioning.	27658542
Inflammation	Altered Intercellular Communication	Our results suggest that systemic inflammation is one biologically plausible mechanism through which differences in body mass might influence changes in cognitive functioning among aging adults.	27658542
Inflammation, Calcified (qualifier), Traumatic injury, Vascular lesions	Altered Intercellular Communication	Inflammation, trauma, debris acting as nidus and vascular lesions have been attributed as principal causes for occurrence of calcifications within the oral mucosa.	27659092
Refractory anemias, Inflammation, Rheumatoid Arthritis, Osteoporosis	Altered Intercellular Communication	This study aimed to investigate the efficacy of denosumab (compared with that of bisphosphonates) for preventing secondary osteoporosis and inflammation caused by excessive bone resorption in Japanese rheumatoid arthritis (RA) patients never previously treated for osteoporosis.	27659808
Refractory anemias, Inflammation, Osteoporosis	Altered Intercellular Communication	Neither denosumab nor bisphosphonates could suppress inflammation or RA disease activity, but denosumab significantly suppressed a marker of bone metabolism in Japanese RA patients never previously treated for osteoporosis.	27659808
Inflammation	Altered Intercellular Communication	Pentraxin 3 (PTX3), an essential component of the innate immunity system that plays a non-redundant role in controlling inflammation, regulates complement by interacting with complement components.	27659908
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	The goal was to identify active compounds in hot aqueous extracts of BL (HAE-BL) that are consistent with a role in reducing inflammation and reducing the vascular pathology associated with diabetes.	27660013
Inflammation, Blood Vessel	Altered Intercellular Communication	All of these properties are consistent with a role in reducing inflammation and reducing vascular leak.	27660013
Inflammation, Liver damage, Acute-On-Chronic Liver Failure	Altered Intercellular Communication	Patients with HBV-related acute-on-chronic liver failure have increased concentrations of extracellular histones aggravating cellular damage and systemic inflammation.	27660136
Inflammation, Hepatitis B, Chronic, CRNKL1 wt Allele, Liver Cirrhosis	Altered Intercellular Communication	We found that plasma histone H4 levels were greatly increased in patients with ACLF as compared with chronic hepatitis B, liver cirrhosis and healthy control subjects and were significantly associated with disease severity, systemic inflammation and outcome.	27660136
Inflammation, Liver damage, CRNKL1 wt Allele	Altered Intercellular Communication	The data support the hypothesis that the increased extracellular histone levels in ACLF patients may aggravate disease severity by inducing cellular injury and systemic inflammation.	27660136
cell injury	Altered Intercellular Communication	Recently, extracellular histones, especially H4, have been recognized as important mediators of cell damage in various inflammatory conditions.	27660136
Extrinsic allergic alveolitis, Pneumonia, Granulomatous inflammation, Drug toxicity, Sarcoidosis	Altered Intercellular Communication	The most frequent histopathologic patterns were granulomatous inflammation (12 patients) and organizing pneumonia (OP) (11 patients), resulting in the final diagnoses of hypersensitivity pneumonitis (six patients), cryptogenic OP (six patients), connective tissue disease-associated OP (three patients), drug toxicity (three patients), infection-related OP (two patients), sarcoidosis (two patients), and aspiration (one patient).	27660154
Malignant neoplasm of urinary bladder, Inflammation, Aggressive behavior	Altered Intercellular Communication	We speculated that a heterogeneous population of non-muscle invasive bladder cancer (NMIBC) patients with a previous history of smoking may be more precisely stratified by a biomarker associated with tumor aggressiveness and then focused on the preoperative neutrophil-to-lymphocyte ratio (pre-NLR), which is a simple index of systemic inflammation.	27660257
Inflammation, Chlamydia trachomatis, Pelvic adhesions	Altered Intercellular Communication	Elevated titers of anti-Chlamydia trachomatis antibodies are frequently associated with laparoscopic evidence of pelvic adhesions and inflammation.	27660878
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The identification of calcium crystals in synovial fluid (SF) of patients with osteoarthritis (OA) represents an important step in understanding the role of these crystals in synovial inflammation and disease progression.	27660935
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The PTEN/Akt pathway is a plausible candidate as it may play a role in mediating inflammation via COX-2, and has been associated with cancer progression.	27661110
Communicable Diseases, Necrotizing fasciitis, Inflammation, Necrosis	Altered Intercellular Communication	Necrotizing fasciitis is an infection of the soft tissue that is characterized by rapidly spreading inflammation and subsequent necrosis.	27662064
Inflammation	Altered Intercellular Communication	Our findings suggest that TREM2 not only plays a critical role in inflammation, but is also involved in neuronal cell survival and in neurogenesis.	27662313
Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	As inflammation plays a major role in neurodegenerative diseases, a lack of TREM2 could be a missing link between immunomodulation and neuroprotection.	27662313
Inflammation, "Alzheimers Disease", Amyloidosis	Altered Intercellular Communication	Acceleration of Amyloidosis by Inflammation in the Amyloid-Beta Marmoset Monkey Model of Alzheimer's Disease.	27662314
Inflammation	Altered Intercellular Communication	The effect of inflammation on amyloidopathy was also investigated in an additional monkey that suffered from chronic inflammatory wasting syndrome.	27662314
Inflammation	Altered Intercellular Communication	Two out of three monkeys injected with Ab and LPS and the additional monkey, suffering from chronic inflammation, developed plaques.	27662314
Inflammation, Scleritis, Surgical reduction	Altered Intercellular Communication	The primary outcome was at least a 2-step reduction or reduction to grade 0 in scleral inflammation on a 0 to +4 scale according to a standardized photographic scleritis grading system by 16 weeks in the study eye compared to baseline.	27663070
Inflammation, Deep thrombophlebitis	Altered Intercellular Communication	These findings favor the hypothesis that inflammation is a cause and not merely a consequence of acute DVT.	27663463
Inflammation, Psoriasis	Altered Intercellular Communication	The evidence that psoriasis is associated with systemic inflammation and significantly higher incidence of cardiovascular risk factors has already been described.	27663919
Inflammation, Glioblastoma Multiforme Pathway	Altered Intercellular Communication	Our findings suggest that radiation induces a rapid enhancement of the prevailing inflammation in high-grade glioma tissue.	27664151
Inflammation, Stomach Carcinoma, Neoplasms	Altered Intercellular Communication	Systemic inflammation is associated with the density of immune cells in the tumor microenvironment of gastric cancer.	27665104
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The neutrophil-lymphocyte ratio (NLR) and the prognostic nutritional index (PNI) are markers of systemic inflammation known to be useful prognostic indicators of malignancy.	27665104
Inflammation, Neoplasms	Altered Intercellular Communication	However, little evidence has defined the influence of inflammation on the tumor microenvironment.	27665104
Inflammation, Stomach Carcinoma, Neoplasms	Altered Intercellular Communication	The NLR and PNI are associated with the density of CD4+ immune cells in the tumor microenvironment, which leads to prognostic values of systemic inflammation in gastric cancer.	27665104
Pancreatic carcinoma	Altered Intercellular Communication	The combination of systemic inflammation-based marker NLR and circulating regulatory T cells predicts the prognosis of resectable pancreatic cancer patients.	27665172
Inflammation, Neoplasms, Pancreatic carcinoma, Impaired	Altered Intercellular Communication	The systemic inflammation response and immune impairment are closely related to the development and progression of various tumours, such as pancreatic cancer.	27665172
Inflammation, Dryness (characteristic)	Altered Intercellular Communication	Thus, the MMP-9 results indicated a clinically significant inflammation in 40% of dry eye patients.	27665213
Dryness (characteristic), Inflammatory abnormality of the eye, Dryness of eye	Altered Intercellular Communication	It correlated well with other dry eye tests and identified the presence of ocular surface inflammation in 40% of confirmed dry eye patients.	27665213
Autoimmune Diseases, Inflammatory abnormality of the eye	Altered Intercellular Communication	It may be especially helpful to identify patients with ocular surface inflammation and autoimmune disease and may facilitate the decision to institute anti-inflammatory treatment in these patients.	27665213
Inflammation, Disorder of mineral metabolism, Endothelial dysfunction, Ventricular Dysfunction, Chronic Kidney Diseases	Altered Intercellular Communication	CKD can contribute to the development and progression of right ventricle dysfunction with endothelial dysfunction, inflammation and mineral metabolism disorders.	27665506
Inflammation, Vascular System Injuries	Altered Intercellular Communication	CXCL16 is both a cholesterol receptor and a chemokine with a potential role in vascular injury and inflammation.	27665581
Communicable Diseases, Inflammation	Altered Intercellular Communication	It should not be reported as a pathological finding on MRI unless clinical findings support regional infection or inflammation.	27666183
HD Term Type, Inflammation, Obesity	Altered Intercellular Communication	Obesity is becoming increasingly common in hemodialysis (HD) patients and is associated with inflammation and increased mortality.	27666944
Inflammation, Atherosclerosis	Altered Intercellular Communication	Many studies have revealed a role of YKL-40 as a new inflammatory biomarker in angiogenesis, inflammation, atherosclerosis and cardiovascular events.	27668705
Communicable Diseases, Inflammation	Altered Intercellular Communication	No pathologic evidence was seen of microorganisms, acute or chronic inflammation, or infection.	27669046
Inflammation	Altered Intercellular Communication	Our data revealed that the variation in Th1, Th17, CXCL16 and homocysteine in peripheral blood of patients with stenting may be implicated in inflammation after intracranial and cervical stent implantation.	27669631
Inflammation	Altered Intercellular Communication	It is mostly difficult to determine the causative agent that causes inflammation in the joints.	27671189
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Regulatory T Cells (Tregs) and Myeloid-Derived Suppressor Cells (MDSCs) are two main regulatory cells modulating the immune responses in inflammation and cancer.	27671508
Inflammation	Altered Intercellular Communication	MSC-SKL-GFP attenuated monocrotaline-induced inflammation, as evidenced by decreased macrophage infiltration around PAs.	27672025
Inflammation	Altered Intercellular Communication	SKL attenuates monocrotaline-induced PA remodeling and PA smooth muscle cell proliferation, likely by reducing inflammation and restoring SIRT1 levels and eNOS activity.	27672025
Inflammation, Traumatic, Spinal Cord Injuries, Stanford Cancer Institute	Altered Intercellular Communication	Inflammation in traumatic spinal cord injury (SCI) has been proposed to promote damage acutely and oppose functional recovery chronically.	27673428
Inflammation, Stanford Cancer Institute	Altered Intercellular Communication	However, we do not yet understand the signals that initiate or prolong inflammation in persons with SCI.	27673428
Inflammation, Stanford Cancer Institute	Altered Intercellular Communication	Together, these data suggest that HMGB1 may be a common, early, and persistent danger signal promoting inflammation in individuals with SCI.	27673428
Inflammation	Altered Intercellular Communication	Highly suggestive cyst wall features are an acellular hyaline lining surrounded by focally calcific fibrous tissue and chronic inflammation.	27673549
Stable chronic Graft vs Host Disease, Inflammation, Fibrosis Assessment, Chronic graft-versus-host disease	Altered Intercellular Communication	Chronic graft-versus-host disease (cGvHD), characterized by inflammation and fibrosis of multiple target organs, considerably contributes to the morbidity and mortality even years after allo-HSCT.	27677743
Inflammation, MTA2 gene, Infertility, Salpingitis, Pelvic Inflammatory Disease	Altered Intercellular Communication	Pelvic inflammatory disease (PID) and more specifically salpingitis (visually confirmed inflammation) is the primary cause of tubal factor infertility and is an important risk factor for ectopic pregnancy.	27678278
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	The results showed a clear association between severe liver pathological conditions (inflammation, steatosis and fibrosis) and (GA + AA) genotypes (P = 0.035, 0.03, 0.04 respectively).	27678360
Fibrosis Assessment, Fatty degeneration, Hepatitis	Altered Intercellular Communication	The stepwise logistic regression analysis showed that the TNFa genotypes (GA + AA) were significantly associated with liver inflammation (OR = 3.776, 95%CI: 1.399-10.194, P = 0.009), severe steatosis (OR = 4.49, 95%CI: 1.441-14.0, P = 0.010) and fibrosis progression (OR = 2.84, 95%CI: 1.080-7.472, P = 0.034).	27678360
Fibrosis Assessment, Fatty degeneration, Hepatitis	Altered Intercellular Communication	Also, the A allele was an independent risk factor for liver inflammation (P = 0.003), steatosis (P = 0.003) and fibrosis (P = 0.014).	27678360
Inflammation, Complication Aspects	Altered Intercellular Communication	Inflammation is one of the primary mechanisms in the development of metabolic complications.	27678438
Autoimmune Chronic Hepatitis, Hepatitis, Insemination, Artificial, Homologous	Altered Intercellular Communication	Autoimmune hepatitis (AIH) is characterised by liver inflammation with reversibility upon anti-inflammatory treatment.	27679428
Inflammation, Liver diseases, Insemination, Artificial, Homologous	Altered Intercellular Communication	Soluble (s)CD163, a specific macrophage activation marker, is associated with inflammation in other liver diseases, but never investigated in AIH.	27679428
Inflammation, Erythema	Altered Intercellular Communication	Keloid redness is due to angiogenesis and chronic inflammation and is an important indicator of the severity of the lesion and the effectiveness of treatment.	27680482
Inflammation, Peripheral Vascular Insufficiency, Blood Coagulation Disorders	Altered Intercellular Communication	Recently, serum lactate level rather than systolic blood pressure (sBP) has been widely used to diagnose peripheral circulatory insufficiency, which often leads to coagulopathy with systemic inflammation.	27680483
Inflammation, Takotsubo Cardiomyopathy	Altered Intercellular Communication	Systemic inflammation has been hypothesized as a possible mechanism of Takotsubo cardiomyopathy (TTC).	27680775
Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Cutaneous Small Vessel Vasculitis	Altered Intercellular Communication	Leukocytoclastic vasculitis (LCV) is a rare small-vessel vasculitis characterised by neutrophilic inflammation of post-capillary venules.	27681337
Inflammation, Tooth Loss	Altered Intercellular Communication	To examine the impact of tooth loss on walking speed over time and explore whether inflammation may account for this association.	27682433
Inflammation, Tooth Loss, Chronic disease, Behavior Disorders	Altered Intercellular Communication	Mixed-effects models showed that tooth loss was associated with a greater decline in walking speed over time after adjustment for lifestyle-related factors and chronic diseases (p = 0.001 for interaction between time and tooth loss on walking speed decline); however, when further adjusting for inflammation (CRP), the association was attenuated and no longer significant.	27682433
Inflammation, Tooth Loss	Altered Intercellular Communication	Inflammation may play a role in the association between tooth loss and walking speed decline.	27682433
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Investigation of a multi-biomarker disease activity score in rheumatoid arthritis by comparison with magnetic resonance imaging, computed tomography, ultrasonography, and radiography parameters of inflammation and damage.	27682742
Inflammation	Altered Intercellular Communication	In the 15 patients who had achieved a Disease Activity Score based on C-reactive protein (DAS28-CRP) < 2.6 at week 26, MRI and/or US detected subclinical inflammation and 13 (87%) had a moderate/high MBDA score.	27682742
Inflammation	Altered Intercellular Communication	In this cohort, the MBDA score correlated poorly with MRI/US inflammation.	27682742
Inflammation, Necrosis	Altered Intercellular Communication	However, the MBDA score and MRI/US were generally concordant in showing signs of inflammation in most patients in clinical remission during anti-tumour necrosis factor (anti-TNF) therapy.	27682742
Inflammation	Altered Intercellular Communication	Markers of inflammation and endothelial activation contributed significantly to CV events, but the limited number of events prevents further analysis.	27682808
Inflammation, Dental Plaque, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	The findings of the present study suggest that cigarette smoking may interfere with several essential parts of the atherosclerosis process, as evidenced by associations with protein markers representing endothelial dysfunction, inflammation, neointimal formation, foam cell formation and plaque instability.	27684606
Inflammation, Fibrosis Assessment, Vasculitis, CTCAE, Waldenstrom Macroglobulinemia	Altered Intercellular Communication	Histology suggested chronic inflammation in spinal dura mater with extensive fibrosis, dense lymphoplasmacytic infiltrate, and focal vasculitis.	27684799
Inflammation, Liver Failure, Acute, Liver damage	Altered Intercellular Communication	Circulating histones are major mediators of systemic inflammation and cellular injury in patients with acute liver failure.	27685635
Inflammation, GTF2A1L wt Allele, Injury of liver	Altered Intercellular Communication	Here we investigated the impact of circulating histones, recently identified inflammatory mediators, on systemic inflammation and liver injury in murine models and patients with ALF.	27685635
Inflammation, GTF2A1L wt Allele	Altered Intercellular Communication	Significant systemic inflammation was also pronounced in ALF patients, which were associated with histone levels.	27685635
Inflammation, Liver damage, Injury of liver	Altered Intercellular Communication	Heparin reduced systemic inflammation and liver damage in mice, suggesting that it could interfere with histone-associated liver injury.	27685635
Inflammation, GTF2A1L wt Allele, Liver damage	Altered Intercellular Communication	Collectively, these findings demonstrate that circulating histones are critical mediators of systemic inflammation and cellular damage in ALF, which may be potentially translatable for clinical use.	27685635
Compact Disk Interactive, Inflammation	Altered Intercellular Communication	CXCL13 is a well-known CXC chemokine involved in inflammation, but its role in CDI remains unknown.	27685937
Inflammation, Foot joint structure	Altered Intercellular Communication	Older age is associated with more MRI-detected inflammation in hand and foot joints.	27686099
Inflammation	Altered Intercellular Communication	Although MRI is recommended for diagnostic use in detecting joint inflammation, its value in clinical practice has not been settled.	27686099
Inflammation	Altered Intercellular Communication	Older symptom-free persons show more MRI-detected inflammation in their hands and feet.	27686099
Refractory anemias, Arthritis, Age of Onset	Altered Intercellular Communication	Because both effects could have diagnostic consequences, we evaluated the association between age-at-onset and MRI-detected inflammation in early arthritis and RA.	27686099
Synovitis, Inflammation, Tenosynovitis	Altered Intercellular Communication	Bone marrow oedema, synovitis and tenosynovitis were summed, yielding the MRI inflammation score.	27686099
Inflammation, Arthritis	Altered Intercellular Communication	Early arthritis and RA-patients had, respectively, 2.6 (95% CI: 2.3, 3.0, P < 0.001) and 3.7 times (95% CI: 3.2, 4.3, P < 0.001) higher MRI inflammation scores than controls (adjusted for age).	27686099
Refractory anemias, Inflammation, Arthritis	Altered Intercellular Communication	At higher age of onset, early arthritis and RA patients had higher MRI inflammation scores (1.03/year, P < 0.001).	27686099
Refractory anemias, Inflammation	Altered Intercellular Communication	At the joint level, older RA patients had more extended MRI inflammation, but the preferential locations were similar.	27686099
Arthritis	Altered Intercellular Communication	Older age is associated with more MRI-detected inflammation, and the effect was similar in arthritis and controls.	27686099
Inflammation, Swelling, With intensity	Altered Intercellular Communication	Spinal magnetic resonance imaging (MRI) revealed longitudinal hyperintensity with cord swelling and hypointensity on T2-weighted images, suggesting severe inflammation and microbleeding change, respectively.	27686688
Prurigo pigmentosa, Inflammation, Sycosis barbae	Altered Intercellular Communication	The frequent presence of bacterial colonies along with sequelae of inflammatory changes on biopsy provides new evidence to support the theory that prurigo pigmentosa is a reactive inflammation associated with bacterial folliculitis.	27686778
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Inflammation plays an important role in the development and progression of CRC.	27686880
Inflammation, Fatigue, Endothelial dysfunction, Lupus Erythematosus, Systemic	Altered Intercellular Communication	Fatigue and cognitive function were assessed and related to SLE activity, clinical data and plasma biomarkers of inflammation and endothelial dysfunction.	27687026
Weight decreased, Pneumonitis	Altered Intercellular Communication	After challenged intranasally with RSV Long, the vaccinated mice showed both decreased lung RSV titers, pulmonary inflammation and body weight loss.	27688078
Inflammation, melanoma	Altered Intercellular Communication	IgG4-related intraocular inflammation masquerading as ciliary body melanoma in a young girl.	27688285
Barrett Esophagus, Inflammation, Adenocarcinoma Of Esophagus	Altered Intercellular Communication	Inflammation plays an important role in the development of esophageal adenocarcinoma and its metaplastic precursor lesion, Barrett's esophagus.	27689189
Carcinogenesis	Altered Intercellular Communication	Toll-like receptor (TLR) 2 signalling and lysosomal function have been linked to inflammation-associated carcinogenesis.	27689189
Avitaminosis, Neurotransmitters, "5-O-(4,4-dimethoxytrityl)thymidine-3-O-(2,4-dinitrophenyl) succinate	Altered Intercellular Communication	Hereditary dopamine transporter deficiency syndrome (DTDS) is a neurotransmitter disorder caused by a defect in the neuronal uptake of dopamine.	27690368
Biological Relative	Altered Intercellular Communication	Both patients had consanguineous parents and similar cerebrospinal fluid (CSF) neurotransmitter profiles with elevated homovanillic acid and increased the ratio of homovanillic acid to 5-hydroxyindoleacetic acid.	27690368
Muscle hypotonia, Oculogyric crisis, Infantile onset, Dystonia Disorders	Altered Intercellular Communication	Early infantile-onset progressive dystonia with oculogyric crises, hypotonia, developmental delay, and CSF neurotransmitter profile led to a diagnosis of DTDS in these two patients.	27690368
Inflammatory abnormality of the eye	Altered Intercellular Communication	Intravitreal sirolimus 440 mg demonstrated a significant improvement in ocular inflammation with preservation of BCVA in subjects with active NIU of the posterior segment.	27692526
Inflammation	Altered Intercellular Communication	Clinical evaluation included assessment of changes in visual acuity, degree of inflammation in the anterior chamber and vitreous cavity, central macular thickness, and retinal angiographic leakage.	27692527
Inflammation, Neoplasms	Altered Intercellular Communication	In recent years, the role of inflammation in the promotion of tumor growth is supported by a broad range of experimental and clinical evidence.	27693669
Bipolar, Pain Distress Question, Inflammation	Altered Intercellular Communication	Concordant pain could be triggered by touching the inflammation with the bipolar radiofrequency probe.	27693825
Inflammation, Granuloma	Altered Intercellular Communication	Old mice (18-21 mo) infected with M. avium had attenuated HO-1 response with diffuse inflammation, high burden of mycobacteria, poor granuloma formation, and decreased survival (45%), while young mice (4-6 mo) showed tight, well-defined granuloma, increased HO-1 expression, and increased survival (95%).	27694475
Inflammation, myocardial injury	Altered Intercellular Communication	Neither additional laboratory parameters for inflammation and myocardial injury nor lung functional measurements differed significantly between the groups.	27695304
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumor necrosis factor-a-induced protein 8-like 2 (TIPE2), a new negative regulator of immunity, plays significant roles in modulating inflammation and tumorigenesis.	27696294
Inflammation, Secondary malignant neoplasm of liver	Altered Intercellular Communication	The prognostic role of systemic inflammation in patients undergoing resection of colorectal liver metastases: C-reactive protein (CRP) is a strong negative prognostic biomarker.	27696432
Inflammation, Neoplasms	Altered Intercellular Communication	Systemic inflammation has been associated with poor survival in several tumor types, but has been less extensively studied in resectable metastatic disease.	27696432
Inflammation, IL13 gene	Altered Intercellular Communication	Effects of leukotriene D4 and histamine nasal challenge on airway responsiveness and inflammation in persistent allergic rhinitis patients.	27696764
Renal Insufficiency, Inflammation	Altered Intercellular Communication	TLT size was associated with impaired renal function and increased expression of proinflammatory cytokines and homeostatic chemokines, indicating a possible contribution of TLTs to sustained inflammation after injury.	27699223
Inflammation, Cytopenia	Altered Intercellular Communication	Shortly after engraftment with UCB, these mice develop a severe, fatal macrophage activation syndrome (MAS) characterized by a progressive drop in rbc numbers, increased reticulocyte counts, decreased rbc half-life, progressive cytopenias, and evidence of chronic inflammation, including elevated human IL-6.	27699249
Inflammation, Fibrosis Assessment, Muscular Atrophy	Altered Intercellular Communication	Hematoxylin Eosin and Azan-Mallory staining were used to detect muscle atrophy, inflammation, and fibrosis, respectively.	27699951
Eosinophilic infiltration of the esophagus, Inflammation, Jersey Island	Altered Intercellular Communication	Four of five patients with JE and NE had severe inflammation with eosinophilic infiltration of the esophageal muscle layer (73.8+-50.3 eosinophils/HPF) with no epithelial eosinophils.	27699951
Heart Diseases, Inflammation, Rheumatoid Arthritis, Degenerative polyarthritis	Altered Intercellular Communication	The administration of krill oil is reported to mitigate inflammation in patients with cardiac disease, rheumatoid arthritis, or osteoarthritis.	27701428
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Plasma pentosidine is markedly elevated in CKD and associates with low GFR, oxidative stress and inflammation, and is an independent predictor of mortality in CKD patients.	27701453
Communicable Diseases, Lower gastrointestinal hemorrhage, Inflammation	Altered Intercellular Communication	The aim of this study was to examine whether low-grade inflammation (LGI) is associated with a subsequently increased risk of infection.	27701463
Cholecystitis, Diverticulitis	Altered Intercellular Communication	We report the case of a patient with evidence of duodenal diverticulitis in association with gallbladder inflammation by contiguity, as well as his diagnosis and management.	27701888
Inflammation, TRPV6 gene	Altered Intercellular Communication	Our data demonstrate that propolis pretreatment shows immunomodulatory effects on both healthy donors and ATL patients adherent cells, increasing IL-4 and IL-17 and decreasing IL-10, in either the presence or absence of the L. braziliensis infection, demonstrating that propolis contributes with the decrease of the inflammation and could also contribute with parasite control.	27702443
Pain Distress Question, Photophobia, Inflammation, Epithelial	Altered Intercellular Communication	Patients with limbal stem cell deficiency (LSCD) often experience pain and photophobia due to recurrent epithelial defects and chronic inflammation of the cornea.	27702552
Inflammation, Data types - Address	Altered Intercellular Communication	Similar to human AD, robust TH1, TH2, and also TH17 activation are seen in IL-23-injected and NC/Nga mice, with similar but weaker inflammation in ovalbumin-challenged mice.	27702671
Inflammation, Psychiatry Specialty, Endothelial dysfunction	Altered Intercellular Communication	All patients underwent brain magnetic resonance imaging; had blood samples taken for markers of inflammation, endothelial dysfunction, cholesterol, and autoantibodies; and underwent cognitive and psychiatric testing.	27703087
Inflammation, Mycoses, Pneumonia	Altered Intercellular Communication	Invasive fungal infection was diagnosed in four patients, idiopathic acute fibrinous and organising pneumonia in three patients, and a granulomatous inflammation of undetermined origin in one patient.	27704258
Acute Lung Injury, Primary malignant neoplasm, Small cell carcinoma of lung	Altered Intercellular Communication	Prognostic Significance of Modified Advanced Lung Cancer Inflammation Index (ALI) in Patients with Small Cell Lung Cancer_ Comparison with Original ALI.	27706243
Acute Lung Injury, Pneumonitis, Small cell carcinoma of lung	Altered Intercellular Communication	Advanced lung cancer inflammation index (ALI, body mass index [BMI] x serum albumin/neutrophil-lymphocyte ratio [NLR]) has been shown to predict overall survival (OS) in small cell lung cancer (SCLC).	27706243
Inflammation, Dryness (characteristic), Autoimmune Disorder, CTCAE	Altered Intercellular Communication	Because TO is a disorder of autoimmune origin, we assumed that the association between TO and dry eye is related to inflammation.	27706674
Inflammation, Neoplasms	Altered Intercellular Communication	Strong evidence suggests that cancer-associated inflammation promotes tumor growth and progression, and interleukin-6 (IL6) is an important modulator of inflammation.	27706719
Hepatitis, Liver Cirrhosis	Altered Intercellular Communication	Macrophages play a key role in liver inflammation and are involved in the pathogenesis of cirrhosis and complications.	27706896
Airway structure, Rhinitis	Altered Intercellular Communication	The incompletely controlled group was older (P < .05), and had more airflow limitation, more airway inflammation, and more severe rhinitis symptoms (all P < .001).	27707660
Inflammation, Primary malignant neoplasm, Hepatitis B	Altered Intercellular Communication	Hepatitis B virus X induces inflammation and cancer in mice liver through dysregulation of cytoskeletal remodeling and lipid metabolism.	27708241
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	A cross-sectional comparison of circulating resistin, sCD40L, as a marker of platelet-mediated inflammation, asymmetric dimethylarginine (ADMA), endothelial dysfunction marker, Dickkopf (DKK)-1, reflecting the inflammatory interaction between platelets and endothelial cells, and urinary 8-iso-PGF2a and 11-dehydro-TxB2, reflecting in vivo lipid peroxidation and platelet activation, respectively, was performed between 79 T2DM patients and 30 healthy subjects.	27709225
Diastolic dysfunction, ETV3 wt Allele	Altered Intercellular Communication	This suggests the important role of sex hormonal effects in the development of LV diastolic dysfunction in relation to MetS in this population.	27710153
Inflammation	Altered Intercellular Communication	Serum and AF LBP levels showed a positive correlation with surrogate markers of inflammation.	27712029
Inflammation, Obesity	Altered Intercellular Communication	The relationship between circulating visfatin/nicotinamide phosphoribosyltransferase, obesity, inflammation and lipids profile in elderly population, determined by structural equation modeling.	27712122
Inflammation	Altered Intercellular Communication	This indicates that circulating visfatin/NAMPT can be considered as a novel surrogate marker of systemic inflammation associated with fat depot, especially visceral, in the elderly population.	27712122
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	The relation between inflammation and prothrombotic state in atrial fibrillation (AF) is well recognized.	27712649
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	This suggests a potential role for high-sensitivity C-reactive protein (hs-CRP), a marker of systemic inflammation, in improving prediction of stroke in participants with AF.	27712649
Inflammation, Chronic Obstructive Airway Disease, Airway Obstruction	Altered Intercellular Communication	Elevated circulating PAI-1 levels are related to lung function decline, systemic inflammation, and small airway obstruction in chronic obstructive pulmonary disease.	27713627
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Plasminogen activator inhibitor-1 (PAI-1) and soluble urokinase-type plasminogen activator receptor (suPAR) participate in inflammation and tissue remolding in various diseases, but their roles in chronic obstructive pulmonary disease (COPD) are not yet clear.	27713627
ARCN1 gene, Inflammation, Airway Obstruction, Ovalocytosis, Malaysian-Melanesian-Filipino Type	Altered Intercellular Communication	This study aimed to investigate if PAI-1 and suPAR were involved in systemic inflammation and small airway obstruction (SAO) in COPD.	27713627
ARCN1 gene, Inflammation, Ovalocytosis, Malaysian-Melanesian-Filipino Type	Altered Intercellular Communication	Our findings first illustrate that elevated serum PAI-1 levels are related to the lung function decline, systemic inflammation, and SAO in COPD, suggesting that PAI-1 may play critical roles in the pathogenesis of COPD.	27713627
Airway structure	Altered Intercellular Communication	Fractional exhaled nitric oxide (FeNO) is an easy, sensitive, reproducible, and noninvasive marker of eosinophilic airway inflammation.	27713629
Celiac Disease, Inflammation	Altered Intercellular Communication	Celiac disease (CD) is an autoimmune condition, characterized by inflammation of the small intestine.	27714440
Hypogammaglobulinemia	Altered Intercellular Communication	Asthma and Hypogammaglobulinemia: an Asthma Phenotype with Low Type 2 Inflammation.	27714565
Inflammation	Altered Intercellular Communication	These patients have low type-2 inflammation markers.	27714565
Inflammation, Obesity	Altered Intercellular Communication	Correlation of TLR4 and KLF7 in Inflammation Induced by Obesity.	27714571
Inflammation, Obesity	Altered Intercellular Communication	Objective Recent studies have revealed a link between toll-like receptors (TLRs), Kruppel-like factors (KLFs), and the adipose tissue inflammation associated with obesity.	27714571
Inflammation, Obesity	Altered Intercellular Communication	TLR4 is associated with chronic inflammation in obesity.	27714571
Inflammation	Altered Intercellular Communication	KLF7 is known to play an important role in the differentiation of adipocytes, but its role in visceral adipose tissue inflammation has not yet been investigated.	27714571
Inflammation, Obesity	Altered Intercellular Communication	Thus, the objective of this study was to determine the correlation of TLR4 and KLF7 in inflammation induced by obesity.	27714571
Inflammation, Obesity	Altered Intercellular Communication	Conclusion Higher expression of TLR4 and KLF7 may play a vital role in the process of inflammation induced by obesity in visceral adipose tissue.	27714571
palladium, Inflammation, Congestive heart failure	Altered Intercellular Communication	The study hypothesis stated that elimination of chronic inflammation caused by PD has a significant impact on inflammation markers and, secondarily, also on the course and prognosis of CHF.	27714722
Inflammation, Overweight	Altered Intercellular Communication	Yeast b-Glucan Modulates Inflammation and Waist Circumference in Overweight and Obese Subjects.	27715351
Inflammation	Altered Intercellular Communication	Increased inflammation occurs with excessive adiposity and yeast b-glucan modulates immune responses.	27715351
Inflammatory abnormality of the eye, Ulcer	Altered Intercellular Communication	Clinically, the ulcers presented as non-infiltrated lesions with a modicum of other ocular inflammation.	27715362
Inflammation, Akkermansia	Altered Intercellular Communication	The link between Akkermansia, gut inflammation and C. difficile colonisation merits further investigations.	27716140
Inflammation, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	It has been reported that higher levels of oxidative stress and inflammation play a key role in the progression of hepatocellular carcinoma (HCC) after surgery.	27716246
Inflammation, FAM126A gene	Altered Intercellular Communication	In conclusion, we demonstrated that a dose of 300 mg/d of coenzyme Q10 supplementation significantly increased the antioxidant capacity and reduced the oxidative stress and inflammation levels in HCC patients after surgery.	27716246
Destruction of tissue, Inflammation	Altered Intercellular Communication	In part A, sarilumab 150 and 200 mg every 2 weeks (q2w) significantly reduced biomarkers of tissue destruction, cartilage degradation, and synovial inflammation at both 2 and 12 weeks posttreatment (p < 0.05 vs placebo).	27716324
Knee Injuries, Inflammation, Fracture	Altered Intercellular Communication	Following knee injury, this activation is instant and associated with inflammation as well as with the presence of osteochondral fractures.	27716448
Inflammation, Observation Method - Coagulation, Ischemia	Altered Intercellular Communication	Classification according to their main function showed alterations related to coagulation, inflammation, oxidative stress, response to ischemia and lipid metabolism, defining 4 different molecular panels that characterize AS with high specificity and sensitivity.	27716559
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	Pembrolizumab has been associated with rapid onset of ocular inflammation and uveitis.	27716999
Inflammation	Altered Intercellular Communication	Tuberculosis-diabetes co-morbidity (TB-DM) is characterized by increased inflammation with elevated circulating levels of inflammatory cytokines and other factors.	27717783
Inflammation	Altered Intercellular Communication	Our data demonstrate that TB-DM is associated with heightened levels of circulating angiogenic factors, possibly reflecting both dysregulated angiogenesis and exaggerated inflammation.	27717783
Inflammation	Altered Intercellular Communication	Inflammation can be acute or chronic based on clinical history, and it can be suppurative based on the presence of micro or macro abscess formation within the substance of the gland.	27717819
Fibrous histiocytoma of tendon sheath	Altered Intercellular Communication	Coexisting sarcoidal granulomatous inflammation and diffuse tenosynovial giant cell tumor of the knee after a total knee replacement: a case report.	27717976
Granulomatous inflammation, Fibrous histiocytoma of tendon sheath	Altered Intercellular Communication	Histologically, the mass from the posterior joint space showed characteristic features of diffuse tenosynovial giant cell tumor, while the synovium from the anterior compartment demonstrated sarcoidal granulomatous inflammation.	27717976
Abnormal renal function, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Individuals with a combination of elevated cathepsin L and increased inflammation, kidney dysfunction, or prevalent cardiovascular disease had a markedly increased risk, while no increased risk was associated with elevated cathepsin L, in the absence of these disease states.	27718373
Asthma, allergic inflammation, Rhinitis, Allergy - Charge Type Reason	Altered Intercellular Communication	Five clusters (designated A through E) were distinguished by indicators of asthma and rhinitis severity, pulmonary physiology, allergy (sensitization and total serum IgE), and allergic inflammation.	27720016
Asthma, Rhinitis	Altered Intercellular Communication	In comparison to other clusters, cluster A was distinguished by lower allergy/inflammation, minimally symptomatic asthma and rhinitis, and normal pulmonary physiology.	27720016
Cluster, Asthma, Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	Cluster B had highly symptomatic asthma despite high step-level treatment, lower allergy and inflammation, and mildly altered pulmonary physiology.	27720016
Inflammation, Asthma, Rhinitis, Allergy - Charge Type Reason	Altered Intercellular Communication	Cluster C had minimally symptomatic asthma and rhinitis, intermediate allergy and inflammation, and mildly impaired pulmonary physiology.	27720016
Asthma, Rhinitis	Altered Intercellular Communication	Clusters D and E exhibited progressively higher asthma and rhinitis symptoms and allergy/inflammation.	27720016
allergic inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	However, a symptomatic phenotype with little allergy or allergic inflammation was identified.	27720016
Obesity, Allergic sensitization, Asthma, allergic inflammation, Rhinitis	Altered Intercellular Communication	On the basis of medical evidence in the published literature, we developed a conceptual model to describe how 8 risk-factor domains (allergen sensitization, allergic inflammation, pulmonary physiology, stress, obesity, vitamin D, environmental tobacco smoke [ETS] exposure, and rhinitis severity) are linked to asthma severity.	27720018
Allergy - Charge Type Reason, Allergic sensitization, Asthma, allergic inflammation, Rhinitis	Altered Intercellular Communication	An allergy pathway (linking allergen sensitization, allergic inflammation, pulmonary physiology, and rhinitis severity domains to asthma severity) and the ETS exposure pathway (linking ETS exposure and pulmonary physiology domains to asthma severity) exerted significant effects on asthma severity.	27720018
Burn Specimen Source Codes, Gastrointestinal inflammation	Altered Intercellular Communication	While the most obvious impact of burn is on the skin, systemic responses also occur after burn, including intestinal inflammation.	27720266
Inflammation, Dental Plaque	Altered Intercellular Communication	Inflammation and angiogenesis play major roles in carotid plaque vulnerability.	27720278
Inflammation, Dental Plaque	Altered Intercellular Communication	Presence of an ultrasound DWA was associated with more plaque hemosiderin (p = 0.0005) and inflammation (p = 0.019) on histopathology examination.	27720278
Uremia, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Cardiac changes observed in chronic kidney disease patients are of multifactorial origin including chronic uremia, hemodynamics or inflammation.	27721315
Inflammation, Dysbiosis	Altered Intercellular Communication	CONCLUSIONS Results suggest dysfunctional immune activation in ILL following exercise and that prokaryotic viruses may contribute to mucosal inflammation and bacterial dysbiosis.	27721367
Refractory anemias, Inflammation, Proteus mirabilis	Altered Intercellular Communication	These results indicate that P. mirabilis through the molecular mimicry mechanism leads to inflammation and damage of the joints in RA.	27722971
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Periodic fever syndrome (PFS) conditions are characterized by recurrent attacks of fever and localized inflammation.	27723279
Airway structure, Asthma	Altered Intercellular Communication	We sought to compare airway inflammation and its relationship to asthma control in aged versus younger patients and determine whether differences are asthma specific or caused by "inflamm-aging."	27725186
Airway structure, Asthma	Altered Intercellular Communication	Knowledge of the aging effect on airway inflammation and asthma control is limited.	27725186
Airway structure, Asthma	Altered Intercellular Communication	We sought to compare airway inflammation and its relationship to asthma control in aged versus younger patients and determine whether differences are asthma specific or caused by "inflamm-aging."	27725186
Airway structure, Asthma	Altered Intercellular Communication	Differences in airway inflammation can contribute to diminished asthma control in the aged.	27725186
Inflammation	Altered Intercellular Communication	The condition is characterized by epithelial proliferation, fibrovascular growth, chronic inflammation, and prominent extracellular matrix remodeling.	27725197
Endophthalmitis, CTCAE, Hypopyon	Altered Intercellular Communication	All presented with aggressive inflammation (hypopyon in two cases) and two were treated for suspected endophthalmitis.	27726461
Keratitis, Episcleritis, Orbital Pseudotumor, Traumatic iritis, Endophthalmitis, CTCAE	Altered Intercellular Communication	Patients with keratitis, episcleritis, orbital inflammation, post-surgical endophthalmitis, traumatic iritis, and corneal graft rejection were excluded.	27726522
Inflammation, Epithelial ovarian cancer	Altered Intercellular Communication	Chronic inflammation has been implicated in the development of epithelial ovarian cancer (EOC); yet the contribution of inflammatory foods and nutrients to EOC risk has been understudied.	27727481
Inflammation, Acute pulmonary embolism, APEX1 protein, human	Altered Intercellular Communication	The relationship between inflammation and mortality after acute pulmonary embolism (APE) has previously been investigated with different variables (platelet/lymphocyte ratio, etc).	27727508
Inflammation	Altered Intercellular Communication	LMR as a novel marker of inflammation seemed to be an independent predictor of short-term mortality in patients with APE.	27727508
Inflammation, Treatment/Psychosocial Effects	Altered Intercellular Communication	Psychosocial distress and inflammation: Which way does causality flow?	27728857
Inflammation, Treatment/Psychosocial Effects	Altered Intercellular Communication	This study queried causal direction in linkages of inflammation with psychosocial distress.	27728857
Inflammation, Anxiety, CTCAE 3.0, Depression, CTCAE	Altered Intercellular Communication	Inflammation was indicated by C-reactive protein, and distress by depression, anxiety, as well as stress.	27728857
Inflammation, Treatment/Psychosocial Effects	Altered Intercellular Communication	Rather than being an outcome of psychosocial distress, inflammation was a predictor of it.	27728857
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Linkages were gender differentiated, with inflammation seeming to induce depression among men but stress among women.	27728857
Inflammation	Altered Intercellular Communication	Contrary to previous literature, inflammation may not be a mechanism through which psychosocial distress gets "under the skin" to cause cardiovascular and metabolic issues.	27728857
Inflammation, Interferon-Related DNA Damage Resistance Gene Signature, Coronary Artery Disease, Vasculitis of large artery	Altered Intercellular Communication	As inflammation may play a role, we wanted to compare the occurrence and extent of inflammatory cell infiltrates (ICIs), small vessel vasculitis, and the amount of adipose tissue and collagen in cardiac biopsies taken from patients with coronary artery disease with and without IRDs.	27729056
Inflammation	Altered Intercellular Communication	Our results do not support the notion that inflammation in cardiac peri-, epi-, and myocardium plays a more important role in CVD of patients with IRD than non-IRD patients.	27729056
Idiopathic Inflammatory Myopathies, IgG4-Related Sclerosing Disease, Pseudotumor	Altered Intercellular Communication	IgG4-related disease (IgG4-RD) is an idiopathic inflammatory condition that causes pseudotumor formation in single or multiple organs, including those of the head and neck.	27729479
Intraocular inflammation	Altered Intercellular Communication	The included cases were all non-HIV-infected patients presenting with intraocular inflammation from 2002 to 2014 at Kyung Hee University Hospital.	27729756
Inflammation, Heart failure	Altered Intercellular Communication	A score composed by these factors (denominated HIS [Heart Failure, Inflammation, and female Sex]) showed a sensitivity of 79% and a specificity of 60% (area under receiver operating characteristic curve 0.695, P = 0.002) in identifying patients with a positive transesophageal echo; traditional risk scores did not perform as well.	27730663
Inflammation, Pathology	Altered Intercellular Communication	Our results suggest that aneuploid cells that accumulate during aging in some mammalian tissues potentially contribute to age-related pathologies and inflammation through SASP secretion.	27731420
Shock, Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	However, animal studies demonstrate that calcium administration during critical illness heightens inflammation and leads to shock, organ dysfunction, and mortality.	27732742
Diarrhea, Inflammation, Dermatitis acneiform, Fatigue	Altered Intercellular Communication	The most common treatment-related adverse events in the 71 patients who received treatment across five dose levels were diarrhea (59.2%), mucosal inflammation (47.9%), and fatigue and acneiform dermatitis (45.1% each).	27733479
Toxic effect, Inflammatory disease of mucous membrane	Altered Intercellular Communication	The most common dose-limiting toxicity was mucosal inflammation.	27733479
Communicable Diseases, Inflammation, Deglutition Disorders	Altered Intercellular Communication	We aimed to confirm that stroke-induced immunodepression syndrome is associated with stroke-associated pneumonia independently from dysphagia by investigating the predictive properties of monocytic HLA-DR expression as a marker of immunodepression as well as biomarkers for inflammation (interleukin-6) and infection (lipopolysaccharide-binding protein).	27733675
Inflammation, Pancreatitis	Altered Intercellular Communication	The disease course of acute pancreatitis (AP) ranges from mild and self-limiting to severe inflammation, associated with significant morbidity and mortality.	27734249
Single organ dysfunction, Inflammation	Altered Intercellular Communication	The a1-microglobulin/creatinine ratio upon presentation with AP is related to inflammation and predicts development of organ failure.	27734249
Inflammation	Altered Intercellular Communication	Abdominal fat has been recognized as the most hormonally active tissue secreting a variety of adipocytokines and, therefore, potentially contributing to inflammation.	27734324
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Inflammation, regeneration and fibrosis are observed at the whole organ level, both in dystrophin-negative and dystrophin-positive portions of the chimeric tissues.	27734557
Inflammation, Crohn Disease	Altered Intercellular Communication	Monitoring mucosal inflammation is crucial to prevent complications and disease progression in Crohn's disease (CD).	27734914
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Clinical activity scores and non-invasive biochemical markers do not correlate well with mucosal inflammation.	27734914
Inflammation, Noncommunicable Diseases	Altered Intercellular Communication	n-3-polyunsaturated fatty acids and polyphenols are potential key factors for the treatment and prevention of chronic inflammation associated to ageing and non-communicable diseases.	27735833
Inflammation, Pain Distress Question	Altered Intercellular Communication	Consecutive nonsteroidal anti-inflammatory-drugs (NSAIDs) poor responders with chronic inflammation and pain due to knee arthrosis were assessed (15 subjects, age: 67.2 +- 7.9, body mass index: 30.6 +- 7.1, men/women:2/13).	27737573
Inflammation, Synovitis	Altered Intercellular Communication	Only the DCE-MRI variable MExNvoxel (surrogate of the volume and degree of synovitis) and the macroscopic score showed correlations above the pre-specified threshold for acceptance with histological inflammation.	27737813
NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology	Altered Intercellular Communication	She had no identifiable inflammatory condition and did not meet the criteria for myelodysplastic syndrome.	27737867
Inflammation, FAM126A gene	Altered Intercellular Communication	Inflammation is closely related to the initiation and development of HCC.	27739418
Inflammation, Liver carcinoma, Liver Cirrhosis, FAM126A gene	Altered Intercellular Communication	However, a long period of elevated systemic venous pressure and low cardiac output after the procedure result in chronic inflammation and liver cirrhosis, which may eventually lead to the occurrence of hepatocellular carcinoma (HCC).	27741102
Inflammation, Sleep Apnea, Obstructive, Impaired cognition, Osage language	Altered Intercellular Communication	Pediatric obstructive sleep apnea (OSA) is associated with chronic systemic inflammation and with cognitive impairments.	27741107
Airway structure	Altered Intercellular Communication	Genetic susceptibility for air pollution-induced airway inflammation in the SALIA study.	27741447
Inflammation	Altered Intercellular Communication	Long-term air pollution exposure has been associated with chronic inflammation providing a link to the development of chronic health effects.	27741447
Airway structure, Inflammatory disorder	Altered Intercellular Communication	Furthermore, there is evidence that pathways activated by endoplasmatic reticulum (ER) stress induce airway inflammation and thereby play an important role in the pathogenesis of inflammatory diseases.	27741447
Inflammation	Altered Intercellular Communication	These results indicate that genetic variation in the ER stress pathway might play a role in air pollution induced inflammation in the lung.	27741447
Inflammation, Pyoderma Gangrenosum	Altered Intercellular Communication	Speed of healing, IGA, and resolution of inflammation were all shown to be good predictors of eventual healing of pyoderma gangrenosum.	27742168
Cell Death, Inflammation	Altered Intercellular Communication	Notably, there is no altered expression in proteins associated with cell death, ubiquitin or inflammation.	27742266
Communicable Diseases, Inflammation	Altered Intercellular Communication	The bronchoalveolar lavage showed marked signs of acute inflammation without recovering any infectious agent.	27742338
Inflammation	Altered Intercellular Communication	Immune aging manifests with a combination of failing adaptive immunity and insufficiently restrained inflammation.	27742546
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	In patients with rheumatoid arthritis (RA), T cell aging occurs prematurely, but the mechanisms involved and their contribution to tissue-destructive inflammation remain unclear.	27742546
Inflammation, Degenerative disorder	Altered Intercellular Communication	Low-grade inflammation is associated with an increased risk of chronic degenerative disease, but its relationship with mortality is less well explored.	27742767
Inflammation, Health-Related Behavior, Chronic disease	Altered Intercellular Communication	As compared to subjects in the lowest quartile of the low-grade inflammation score, those in the highest category had a significantly increased risk in overall mortality (HR=1.44; 1.17-1.77), independently of possible confounders, including the presence of chronic diseases and a number of health-related behaviors.	27742767
Inflammation, diabetic, Cardiovascular Diseases	Altered Intercellular Communication	The magnitude of the association of low-grade inflammation with mortality was relatively higher in type 2 diabetic patients (HR=2.90; 1.74-4.84) and in individuals with a history of cardiovascular disease (HR=2.48; 1.50-4.11) as compared to their counterparts who were free from the disease.	27742767
Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	The neutrophil-to-lymphocyte ratio (NLR) is a marker that reflects systemic inflammation and organ dysfunction.	27743125
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Observational associations between inflammation and cardiovascular disease are interesting, but randomised experimental data are lacking.	27744141
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The effect inflammation has on cancer prognosis is marked by the presence of cytokines and chemokines.	27744625
Primary malignant neoplasm, Acute inflammation, Cardiovascular Diseases	Altered Intercellular Communication	A total of 23 233 middle-aged participants (8862 men and 14 371 women) who were free from cardiovascular disease, cancer, and acute inflammation (defined by a CRP level >=10 mg/L) were drawn from 11 rural communities in Korea between 2005 and 2011.	27744669
FTO protein, human, Inflammation	Altered Intercellular Communication	Relationships between the intestinal microbiota, intestinal permeability and inflammation in the context of risk for obesity-associated disease continue to be of interest.	27745826
Chronic inflammation	Altered Intercellular Communication	Defective Signaling in the JAK-STAT Pathway Tracks with Chronic Inflammation and Cardiovascular Risk in Aging Humans.	27746093
Inflammation	Altered Intercellular Communication	Chronic inflammation, a decline in immune responsiveness, and reduced cardiovascular function are all associated with aging, but the relationships among these phenomena remain unclear.	27746093
Inflammation	Altered Intercellular Communication	Targeting chronic inflammation may ameliorate this deficiency in cellular responsiveness and improve cardiovascular function.	27746093
nervous system disorder, Communicable Diseases, Inflammation, Systemic disease	Altered Intercellular Communication	The reference standard was the diagnosis classified into five categories: 1) CNS infection; 2) CNS inflammation without infection; 3) other neurological disorder; 4) non-neurological infection; and 5) other systemic disorder.	27746160
ARCN1 gene, Inflammation	Altered Intercellular Communication	A subset of patients with COPD demonstrates eosinophilic inflammation either in their sputum or blood.	27746201
Inflammation, Bacterial Infections	Altered Intercellular Communication	Dusquetide, a novel Innate Defense Regulator, modulates the innate immune system at a key convergence point in intracellular signaling pathways and has demonstrated activity in both reducing inflammation and increasing clearance of bacterial infection.	27746305
Inflammation	Altered Intercellular Communication	However, KCOTs with intense inflammation showed higher Ki-67 expression (p < 0.001).	27747382
Granulomatous inflammation, Sarcoidosis, Granulomatous disorder	Altered Intercellular Communication	Given the multisystem involvement with significant chest findings, tissue findings of granulomatous disease, and negative workup for other causes of granulomatous inflammation, both cases were diagnosed with active disseminated sarcoidosis, and treated with corticosteroids.	27748327
Gastrointestinal inflammation	Altered Intercellular Communication	The role of IL-33 in intestinal inflammation is incompletely understood, with both pro-inflammatory and regulatory properties described.	27748438
Inflammatory Bowel Diseases, Tumor necrosis, Rheumatoid Arthritis	Altered Intercellular Communication	Tumor necrosis factor alpha (TNF alpha) antagonists are biologic agents used in the management of inflammatory conditions such as rheumatoid arthritis, seronegative spondyloarthropathies and inflammatory bowel disease.	27748629
Refractory anemias, Inflammation, PROS1 gene, Synovitis	Altered Intercellular Communication	Polyarticular PsA patients in remission had lower levels of local (US synovitis) and systemic inflammation than RA patients in remission, even though a significantly higher percentage of PsA patients were on tapered doses of anti-TNF, mainly in monotherapy.	27749227
Musculoskeletal, Inflammation, Psoriasis	Altered Intercellular Communication	Part of the psoriasis patients with musculoskeletal complaints will have inflammation of the entheses.	27749228
Inflammation	Altered Intercellular Communication	Active ultrasound inflammation contained positive power Doppler signal or in case of the plantar aponeurosis increased thickness.	27749228
Inflammation, Sore to touch, Pain Distress Question	Altered Intercellular Communication	Active ultrasound inflammation accompanied with pain or tenderness at the enthesis was found in 36% of the patients (n=40).	27749228
Inflammation, Synovitis	Altered Intercellular Communication	MRI synovitis was not correlated with radiological scores, clinical or biologic markers of inflammation.	27749237
Ischemia, Inflammation, Ulcer	Altered Intercellular Communication	Ischaemia was defined as lower blood flow or skin temperature (and inflammation as higher) within the ulcer, compared to a non-affected site.	27749241
Inflammation, Ulcer	Altered Intercellular Communication	Inflammation in the surrounding area was identified for all ulcers by LDI but not thermography.	27749241
Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	We examined relationships between psychological constructs and markers of inflammation, endothelial function, and myocardial strain in a cohort of post-acute coronary syndrome (ACS) patients.	27749683
Inflammation, Anxiety, CTCAE 3.0, Amino-terminal pro-brain natriuretic peptide, Endothelial dysfunction, Bipolar Disorder	Altered Intercellular Communication	In concurrent analyses, depressive symptoms were associated with elevated markers of inflammation (interleukin-17: b = .047; 95% confidence interval [CI] = .010-.083]), endothelial dysfunction (endothelin-1: b = .020; 95% [CI] = .004-.037]), and myocardial strain (N-terminal pro-B-type natriuretic peptide: b = .045; 95% [CI] = .008-.083]), independent of age, sex, medical variables, and anxiety, whereas anxiety was not associated with these markers in multivariable adjusted models.	27749683
Inflammation, Bipolar Disorder, Myocardial, Endothelial dysfunction, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Depressive symptoms were associated with more inflammation, myocardial strain, and endothelial dysfunction in the 6 months after ACS, whereas positive psychological constructs were linked to better endothelial function.	27749683
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histologic fibrosis was staged and inflammation activity was graded based on the METAVIR scoring system on liver biopsy specimens.	27750231
Inflammation, Fibrosis Assessment, Liver Stiffness	Altered Intercellular Communication	The liver stiffness values by using 2D SWE and RTE both increased in parallel with the degree of liver fibrosis and the grade of inflammation.	27750231
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	These toxins induce inflammation and are associated with cardiovascular disease (CVD).	27751361
Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	Monocytes are known to play a key role in the initiation and progression of atherosclerosis and contribute to plaque destabilization through the generation of signals that promote inflammation and neoangiogenesis.	27751505
Inflammation, Thrombophilia	Altered Intercellular Communication	The coincidence of hyper-coagulation, cell senescence, and inflammation suggests the existence of a common underlying mechanism.	27752126
Inflammation, Sore to touch	Altered Intercellular Communication	He presented with normal vital signs, tenderness in upper abdominal quadrants, elevated lipase (909 units/L), lactate dehydrogenase (193 units/L), and an enlarged pancreas with surrounding inflammation on computed tomography.	27753588
Inflammation	Altered Intercellular Communication	Activated monocytes induce almost all tissue factor (TF) expression contributing to inflammation and coagulation.	27753793
Acute inflammation	Altered Intercellular Communication	In MH and ERM, topical diclofenac and betamethasone equally suppressed postoperative inflammation after the combined surgery, although diclofenac better controlled postoperative IOP.	27754737
Inflammation	Altered Intercellular Communication	In DME and RRD, both drugs were equally effective in suppressing inflammation and controlling IOP, but diclofenac showed weaker suppression following longer operation.	27754737
Inflammatory Bowel Diseases	Altered Intercellular Communication	Fecal HMGB1 Reveals Microscopic Inflammation in Adult and Pediatric Patients with Inflammatory Bowel Disease in Clinical and Endoscopic Remission.	27755215
Inflammation	Altered Intercellular Communication	Fecal high mobility group box 1 (HMGB1) has been suggested to be a novel noninvasive biomarker of gut inflammation.	27755215
Inflammatory Bowel Diseases, Inflammation, Gastrointestinal inflammation	Altered Intercellular Communication	We aimed to assess the reliability of fecal HMGB1, compared with fecal calprotectin (FC), in detecting intestinal inflammation in pediatric and adult patients with inflammatory bowel disease (IBD) and to evaluate the accuracy of HMGB1 in identifying patients with IBD in clinical and endoscopic remission who still have histologic features of inflammation.	27755215
Inflammation, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	Moreover, in patients with clinical and endoscopic remission only fecal HMGB1 showed a strong match with the degree of histological scores of inflammation (CGHAS/IGHAS for Crohn's disease and Geboes Score for ulcerative colitis).	27755215
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Fecal HMGB1 is confirmed to be a reliable biomarker of intestinal inflammation; indeed, it significantly correlates with fecal calprotectin in pediatric and adult IBD patients.	27755215
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Moreover, only fecal HMGB1 identifies histologic inflammation in subjects with IBD in clinical and endoscopic remission.	27755215
malignant disease, Inflammation, Traumatic injury, Communicable Diseases	Altered Intercellular Communication	Six older than 60 years old volunteers in both genders, 40 young female volunteers (no contraceptive drug, n = 18, contraceptive drug, n = 9, lactation, n = 9, pregnant, n = 4) were collected with following exclusion criteria, malignant disease, inflammation, infection, trauma and taking non-steroid anti-inflammatory drugs and antibiotics.	27755396
Symphysis Pubis Dysfunction	Altered Intercellular Communication	Decreases in PTH level can result from medical intervention (MPD) and surgical parathyroidectomy (PTX), or may occur spontaneously, usually associated with an underlying malnutrition-inflammation syndrome (SPD).	27756251
Inflammation, Stomach Neoplasms, Infection caused by Helicobacter pylori, Gastritis, Atrophic	Altered Intercellular Communication	Assessment of 18F-FDG uptake in the stomach reflecting active inflammation is useful in predicting patients with H. pylori infection and subsequent chronic atrophic gastritis which is closely associated with the risk of gastric neoplasms.	27756255
Papilledema, Vitreous inflammatory cells, Retinal Vasculitis, Retinal Hemorrhage, Unspecified visual loss, Infiltration	Altered Intercellular Communication	Acute Multifocal Hemorrhagic Retinal Vasculitis (AMHRV) is a rare disease with unknown incidence that presents with abrupt onset of visual loss associated with retinal vasculitis, retinal hemorrhage, non-confluent posterior retinal infiltrates, vitreous cellular inflammation and papillitis in, otherwise, healthy adult individuals.	27756269
Osteolysis	Altered Intercellular Communication	Lentivirus-mediated short hairpin RNA interference targeting TNF-alpha in macrophages inhibits particle-induced inflammation and osteolysis in vitro and in vivo.	27756280
Inflammation, PPP3CB wt Allele	Altered Intercellular Communication	Although it is known that immune reaction of LNB patients is dominated by Th1 and Th2 responses and patients have elevated numbers of B cells in their cerebrospinal fluid (CSF), not all the cells involved in inflammation and cytokine secretion have been characterized.	27756335
Airway structure, ARCN1 gene, Asthma	Altered Intercellular Communication	In conclusion, sputum biomarkers reflecting both airway inflammation and remodeling of the tissue show potential in differentiation between asthma, COPD, and ACOS.	27757028
Inflammation, hepcidin, Metabolic Syndrome X	Altered Intercellular Communication	This association persisted within strata defined by markers of the metabolic syndrome, markers of inflammation, or other markers of iron homeostasis, including hepcidin.	27758018
Autoimmune Diseases, Fibrosis Assessment, Lupus Erythematosus	Altered Intercellular Communication	Pristane-Accelerated Autoimmune Disease in (SWR X NZB) F1 Mice Leads to Prominent Tubulointerstitial Inflammation and Human Lupus Nephritis-Like Fibrosis.	27760209
Fibrosis Assessment, Interstitial inflammation, Disease	Altered Intercellular Communication	These include i) a stronger upregulation of the cytosolic nucleic acid sensing pathway, which is thought to be key component of the pathogenesis of the human disease, and ii) more prominent kidney interstitial inflammation and fibrosis, which have been both associated with poor prognosis in human LN.	27760209
Fibrosis Assessment, Conjunctivitis	Altered Intercellular Communication	Fifty-seven patients with OcMMP underwent detailed examination of conjunctival inflammation and fibrosis using fornix depth measurement.	27760272
Conjunctival shrinkage, Inflammation	Altered Intercellular Communication	Notably, eyes with no visible inflammation and raised conjunctival neutrophils were more likely to progress and have a greater degree of conjunctival shrinkage compared to those without raised neutrophils.	27760272
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	FDG and F-2-fluorodeoxysorbitol (F-FDS) PET were performed to differentiate malignancy from inflammation.	27764039
Inflammation, Injury of liver	Altered Intercellular Communication	Hyperfibrinolysis may occur due to systemic inflammation or hepatic injury that occurs during liver resection.	27765582
Inflammation, Disease	Altered Intercellular Communication	Such an epigenetic signature may increase risk for diseases exacerbated by inflammation, and may contribute to health disparity.	27765646
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	Current posttraumatic stress disorder and exaggerated threat sensitivity associated with elevated inflammation in the Mind Your Heart Study.	27765647
Post-Traumatic Stress Disorder, Inflammation, Psychiatric	Altered Intercellular Communication	Elevated inflammation has been repeatedly observed in posttraumatic stress disorder (PTSD), and it may drive the development of both psychiatric symptoms and physical comorbidities.	27765647
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	However, it is not clear if elevated inflammation is a feature of both remitted and current PTSD, and little is known about relationships between specific clusters of PTSD symptoms and inflammation.	27765647
Inflammation	Altered Intercellular Communication	Exaggerated threat sensitivity, as indexed by threat reactivity and avoidance of perceived threats, may be particularly closely associated with inflammation.	27765647
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	Our data indicate that elevated inflammation may be a feature of current, but not remitted, PTSD.	27765647
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	Within patients with PTSD, higher threat reactivity was also associated with elevated inflammation.	27765647
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	A better understanding of the relationship between threat sensitivity and inflammation may inform interventions for patients with PTSD.	27765647
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Isocaloric Diets High in Animal or Plant Protein Reduce Liver Fat and Inflammation in Individuals With Type 2 Diabetes.	27765690
Inflammation, Obesity	Altered Intercellular Communication	Ceramides are molecular lipids implicated in apoptosis, inflammation, obesity, and insulin resistance.	27765765
Inflammation, Anemia, Liver Dysfunction	Altered Intercellular Communication	They were characterized by anemia (low hemoglobin and hematocrit levels), inflammation (high leukocyte count, neutrophil count, C-reactive protein level, and body temperature), and hepatic and renal dysfunction (high aspartate aminotransferase, alanine aminotransferase and blood urea nitrogen levels).	27766023
Inflammation	Altered Intercellular Communication	Structural brain changes and all-cause mortality in the elderly population-the mediating role of inflammation.	27766478
Inflammation	Altered Intercellular Communication	While MRI brain changes have been related to mortality during ageing, the role of inflammation in this relationship remains poorly understood.	27766478
Inflammation, Atrophic	Altered Intercellular Communication	Our study supports a possible role for inflammation in the atrophy pathogenesis.	27766478
Necrotizing granulomatous inflammation	Altered Intercellular Communication	A combination of TB PCR, mycobacterial culture, and finding of necrotizing granulomatous inflammation provided the best diagnostic performance (sensitivity, specificity, positive predictive value, negative predictive value, and AUC of 75.0%, 100.0%, 100.0%, 95.6%, and 0.88, respectively).	27766918
Inflammation, Aortic Aneurysm, Atherosclerosis	Altered Intercellular Communication	Angiogenesis and inflammation are implicated in aortic aneurysm and atherosclerosis and regulated by angiopoietin-2 (Angpt2).	27767064
Inflammation, Aortic Aneurysm, Atherosclerosis	Altered Intercellular Communication	In conclusion, administration of rAngpt2 attenuated angiotensin II-induced aortic aneurysm and atherosclerosis in ApoE-/- mice associated with reduced aortic inflammation and angiogenesis.	27767064
Inflammation	Altered Intercellular Communication	The prognostic value of oxidative stress and inflammation in Chinese hemodialysis patients.	27767372
Inflammation	Altered Intercellular Communication	There is limited information about oxidative stress and inflammation on the mortality of Chinese hemodialysis (HD) patients.	27767372
Sepsis, Inflammation, Thrombosis	Altered Intercellular Communication	Soluble CD40 ligand (sCD40L) has been considered as a marker of thrombosis and inflammation in several diseases, including sepsis.	27767979
Inflammation, Septic Shock	Altered Intercellular Communication	Therefore, herein we evaluated association between sCD40L and markers of hemorheology and inflammation on context of septic shock.	27767979
Inflammation, Septic Shock	Altered Intercellular Communication	These results seem to highlight a possible association of sCD40L to endothelial function and inflammation in septic shock context.	27767979
Inflammation	Altered Intercellular Communication	FDG uptake in some of these lesions is suggestive of chronic inflammation.	27768632
Periorbital Infection, Orbital Pseudotumor	Altered Intercellular Communication	Transient episodes of orbital inflammation were noted after retrobulbar injections, but progression of orbital infection was halted and visual acuity restored with eventual hospital discharge.	27768642
Orbital Pseudotumor	Altered Intercellular Communication	However, physicians should be aware of the risk of transient orbital inflammation secondary to retrobulbar amphotericin B deoxycholate.	27768642
Inflammation, Neoplasms	Altered Intercellular Communication	In summary, loss of ASC driven tumor development is counterbalanced in the identical cell by the inhibition of pro-tumorigenic inflammation in the tumor cell itself.	27768771
ARCN1 gene, Inflammation	Altered Intercellular Communication	Combination prednisolone and low-dose cyclosporine A therapy inhibits these pro-inflammatory cells and may reduce systemic inflammation in COPD.	27769261
Inflammation, Malnutrition	Altered Intercellular Communication	The pathophysiology of individuals, considered to be malnourished in rich countries and in areas with endemic malnutrition, results predominantly from deficient nutrition combined with infection/inflammation.	27769782
Inflammation, Malnutrition	Altered Intercellular Communication	We therefore advise to consider the pathophysiology of malnourished individuals leading to inclusion of the following elements in the definition of malnutrition: a disordered nutritional state resulting from a combination of inflammation and a negative nutrient balance, leading to changes in body composition, function and outcome.	27769782
Inflammation, Cholangiocarcinoma, Tissue damage, Hepatobiliary Disorder, FBN2 wt Allele	Altered Intercellular Communication	The carcinogenic liver fluke Opisthorchis viverrini causes chronic inflammation in the bile duct and resulting in unremitting tissue damage that lead to hepatobiliary diseases, including cholangiocarcinoma (CCA).	27769807
atherosclerotic	Altered Intercellular Communication	Objectives Platelet-to-lymphocyte ratio is a novel biomarker, recently shown to be correlated with atherosclerotic inflammation.	27770030
Fracture	Altered Intercellular Communication	Inflammation surrounding such fractures may destroy tissue planes, making dissection more technically difficult.	27770081
Inflammation, Coronary Arteriosclerosis, Myocardium	Altered Intercellular Communication	PZ deficiency is found in AMI patients and could potentially reflect the myocardium injury, local coagulation activation and inflammation response during the acute phase of coronary atherosclerosis disease.	27770663
Inflammation, Blood Vessel	Altered Intercellular Communication	The main outcomes will be markers of lipid and DNA oxidation, inflammation, and vascular damage.	27770787
Inflammation, Rheumatoid Arthritis, Arthritis	Altered Intercellular Communication	Body mass index and extent of MRI-detected inflammation: opposite effects in rheumatoid arthritis versus other arthritides and asymptomatic persons.	27770823
Refractory anemias, Inflammation, Foot joint structure	Altered Intercellular Communication	We hypothesized that the phenomenon is caused by an inverse relationship between BMI and inflammation in hand and foot joints with RA.	27770823
Refractory anemias, Inflammation, Arthritis	Altered Intercellular Communication	To explore this hypothesis, local inflammation was measured using magnetic resonance imaging (MRI) in early arthritis patients presenting with RA or other arthritides and in asymptomatic volunteers.	27770823
Synovitis, Inflammation, Tenosynovitis, Edema of bone marrow	Altered Intercellular Communication	Each MRI scan was scored by two readers on synovitis, bone marrow edema (BME), and tenosynovitis; the sum yielded the total MRI inflammation score.	27770823
Refractory anemias, Inflammation, Arthritis	Altered Intercellular Communication	A higher BMI was associated with higher MRI inflammation scores in arthritides other than RA (b = 1.082, p < 0.001) and in asymptomatic volunteers (b = 1.029, p = 0.040), whereas it was associated with lower MRI inflammation scores in RA (b = 0.97, p = 0.005).	27770823
Inflammation, Synovitis, Refractory anemias, Arthritis, Tenosynovitis	Altered Intercellular Communication	Evaluating the different types of inflammation, a higher BMI was associated with higher synovitis, BME, and tenosynovitis scores in arthritides other than RA (respectively b = 1.084, p < 0.001, b = 1.021, p = 0.24, and b = 1.054, p = 0.003), but with lower synovitis and BME scores in RA (respectively b = 0.98, p = 0.047 and b = 0.95, p = 0.002).	27770823
Thrombotic Microangiopathies, Inflammation	Altered Intercellular Communication	Complement activation, inflammation and relative ADAMTS13 deficiency in secondary thrombotic microangiopathies.	27771173
Inflammation, 5-Trimethoxyamphetamine	Altered Intercellular Communication	Our results indicate that the secondary TMA syndrome and its poor outcome is characterized by relative ADAMTS13 deficiency, inflammation, and complement activation with consumption via the classical and alternative pathways.	27771173
Inflammation, Dental Plaque	Altered Intercellular Communication	Randomized Trial of Plaque-Identifying Toothpaste: Decreasing Plaque and Inflammation.	27771276
Inflammation, Dental Plaque	Altered Intercellular Communication	Randomized data are sparse about whether a plaque-identifying toothpaste reduces dental plaque and nonexistent for inflammation.	27771276
Inflammation, Atherosclerosis, Cardiovascular Diseases	Altered Intercellular Communication	Inflammation is intimately involved in the pathogenesis of atherosclerosis and is accurately measured by high-sensitivity C-reactive protein (hs-CRP), a sensitive marker for cardiovascular disease.	27771276
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The observed reduction in inflammation supports the hypothesis of a reduction in risks of cardiovascular disease.	27771276
Inflammation	Altered Intercellular Communication	Histology revealed that invasive H pylori were more commonly associated with chronic inflammation, in both the antrum (15/15 chronic, 8/15 acute) and fundus (17/18 chronic, 8/18 acute).	27771376
Malnutrition, Comorbidity	Altered Intercellular Communication	Frailty Score significantly correlated with Charlson's comorbidity score (r = 0.40, p < 0.0001), Malnutrition Inflammation Score (r = 0.59, p < 0.0001), and inversely with Subjective Global Assessment score (r = -0.44, p < 0.0001).	27771713
Inflammation, Psychiatric, Data types - Address	Altered Intercellular Communication	Although we failed to find a direct relationship between AD and the genetic variants investigated, possible connections with inflammation and psychiatric symptoms were suggested.	27772752
Inflammation, Ischemic stroke	Altered Intercellular Communication	Association of TLR8 gene rs3764880 polymorphisms with susceptibility and lipid metabolism- and inflammation response-related quantitative traits of ischemic stroke in southern Chinese Han male population.	27772795
Inflammation	Altered Intercellular Communication	TLRs have an important function in inflammation and lipid metabolism.	27772795
Inflammation, Blood Clot	Altered Intercellular Communication	There were no differences in patient comorbidities; however, symptomatic patients more frequently presented with thrombus (n = 10; 67% vs n = 1; 10%; P = .01) and inflammation (n = 8; 53% vs n = 1; 10%; P = .04), and trended toward increased stenosis (n = 12; 80% vs n = 4; 40%; P = .09) compared with asymptomatic patients.	27773728
Inflammation	Altered Intercellular Communication	Among patients treated nonoperatively, no patients complained of symptoms at follow-up, and 50% of those with inflammation on initial imaging had resolution.	27773728
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Low birth weight (LBW) has been considered as a risk factor for adult hypertension that is associated with deterioration of autonomic functions and low-grade inflammation.	27773909
Inflammation	Altered Intercellular Communication	We propose that LBW leads to blunted autonomic responses and low-grade inflammation in seemingly healthy Mongolian adults.	27773909
Amyotrophic Lateral Sclerosis, Inflammation, Nerve Degeneration	Altered Intercellular Communication	Pathophysiological mechanisms that contribute to neurodegeneration in Amyotrophic Lateral Sclerosis (ALS) include oxidative stress and inflammation.	27774920
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	We confirmed the systemic alteration of both the redox and the inflammation status in ALS patients, and we observed a link with some clinical parameters.	27774920
Laryngitis	Altered Intercellular Communication	Prolonged diffuse laryngeal inflammation from smoking and/or reflux is commonly diagnosed as chronic laryngitis and treated empirically with expensive drugs that have not proven effective.	27775059
Hour	Altered Intercellular Communication	Higher number of HRS, larger area of IFAF and presence of SND may indicate a prevalent inflammatory condition in DME with specific response to targeted treatment.	27775223
Inflammatory abnormality of the eye	Altered Intercellular Communication	The primary endpoint was the control of ocular inflammation.	27775458
Inflammatory abnormality of the eye	Altered Intercellular Communication	Ocular inflammation was controlled at 3 months for 80.9% of patients, at 6 months for 94.7%, at 12 months for 83.3%, and at >12 months for 86.7%.	27775458
Inflammation, Malignant Neoplasms, Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia	Altered Intercellular Communication	Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia and Granulomatous Inflammation Mimicking High-Grade Malignancy on FDG-PET/CT.	27775945
Necrotizing granulomatous inflammation, Aggressive course	Altered Intercellular Communication	We report an unusual case of DIPNECH colocalizing with necrotizing granulomatous inflammation mimicking high-grade aggressive malignancy on FDG-PET and a typical case of DIPNECH for comparison with low FDG avidity.	27775945
Inflammation, Impaired cognition, Postoperative delirium	Altered Intercellular Communication	Inflammation after cardiopulmonary bypass may contribute to postoperative delirium and cognitive dysfunction.	27775998
Inflammation, Obesity	Altered Intercellular Communication	It is also associated with markers of obesity and inflammation.	27776152
methyldopa, Inflammation, Drusen	Altered Intercellular Communication	It is established that inflammation contributes to the pathogenesis of drusen and AMD.	27776188
Inflammation, Drusen	Altered Intercellular Communication	Systemic inflammation may contribute to drusen formation in monkeys.	27776188
Inflammation, Amyloidosis	Altered Intercellular Communication	Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly.	27776263
Inflammation	Altered Intercellular Communication	AD brains feature an inflammatory reaction around amyloid plaques, and a specific subset of the gut microbiota (GMB) may promote brain inflammation.	27776263
Inflammation, Amyloidosis, Data types - Address	Altered Intercellular Communication	We investigated the possible role of the GMB in AD pathogenesis by studying the association of brain amyloidosis with (1) GMB taxa with pro- and anti-inflammatory activity; and (2) peripheral inflammation in cognitively impaired patients.	27776263
Inflammation, Amyloidosis	Altered Intercellular Communication	A possible causal relation between GMB-related inflammation and amyloidosis deserves further investigation.	27776263
Inflammation, Axonal loss, Edema	Altered Intercellular Communication	A nerve biopsy showed lymphocyte infiltration (including cytotoxic CD8 cells), oedema, marked axonal loss and myelin-positive macrophages, indicating florid inflammation.	27776522
Inflammation, Injury of kidney, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	Elevated mass and activity of Lp-PLA2 related to inflammation and atherosclerosis may take part in the development of kidney injury and atherosclerosis in patients with CKD.	27776715
Inflammation, Obesity, Diverticular Diseases	Altered Intercellular Communication	Adipose tissue secretes inflammatory cytokines, and chronic inflammation may account for the link between obesity and a more severe presentation of diverticular disease.	27778168
Inflammation, Fatty degeneration	Altered Intercellular Communication	The analysis of association with the disease severity showed that carriers of the A-allele had lower degree of histological steatosis (1.76 +- 0.83 vs. 2.19 +- 0.78, P = 0.03) and lower scores of lobular inflammation (0.54 +- 0.65 vs. 0.95 +- 0.92, P = 0.02) and NAFLD-Activity Score (2.9 +- 1.4 vs. 3.7 +- 1.4, P = 0.015) compared with noncarriers.	27778410
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Magnetic resonance data were used to define the liver inflammation and fibrosis score (LIF 0-4).	27778429
Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Biopsies were assessed for steatosis, lobular inflammation, ballooning and fibrosis and classified as non-alcoholic steatohepatitis or simple steatosis, and mild or significant (Activity >=2 and/or Fibrosis >=2 as defined by the Fatty Liver Inhibition of Progression consortium) non-alcoholic fatty liver disease.	27778429
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Fibrosis stage on biopsy correlated with liver inflammation and fibrosis (rs =.51, P<.0001).	27778429
Fibrosis Assessment, Hepatitis, Liver Cirrhosis	Altered Intercellular Communication	The area under the receiver operating curve using liver inflammation and fibrosis for the diagnosis of cirrhosis was 0.85.	27778429
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Liver inflammation and fibrosis score for ballooning grades 0, 1 and 2 was 1.2, 2.7 and 3.5 respectively (P<.05) with an area under the receiver operating characteristic curve of 0.83 for the diagnosis of ballooning.	27778429
Nonalcoholic Steatohepatitis, Fibrosis Assessment, Fatty degeneration, Hepatitis	Altered Intercellular Communication	Patients with steatosis had lower liver inflammation and fibrosis (1.3) compared to patients with non-alcoholic steatohepatitis (3.0) (P<.0001); area under the receiver operating characteristic curve for the diagnosis of non-alcoholic steatohepatitis was 0.80.	27778429
Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Hepatitis	Altered Intercellular Communication	Liver inflammation and fibrosis scores for patients with mild and significant non-alcoholic fatty liver disease were 1.2 and 2.9 respectively (P<.0001).	27778429
Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Hepatitis	Altered Intercellular Communication	The area under the receiver operating characteristic curve of liver inflammation and fibrosis for the diagnosis of significant non-alcoholic fatty liver disease was 0.89.	27778429
Inflammation, Blood Vessel, Necrosis	Altered Intercellular Communication	The benefits of this treatment, however, are often accompanied with a higher risk of major complications and blood vessel damage because of radiation-induced inflammation and necrosis of the vessel wall.	27778451
Inflammation, melanoma	Altered Intercellular Communication	The molecular and cellular mechanisms behind the involvement of inflammation in melanoma have not been fully elucidated.	27779100
Inflammation, Meibomian gland dysfunction, Fibrosis Assessment, Dual-affinity B7-H3/CD3-targeted Protein MGD009, Dryness of eye	Altered Intercellular Communication	IVCM application provides a strong support to differentiate dry eye patients with different symptoms: meibomian gland dysfunction (MGD) plays a pivotal role in dry eye aggravation, and using IVCM to observe MG fibrosis, changes in size and density of MG as well as status of inflammation cells can help not only correctly diagnose the type and severity of dry eye, but also possibly prognosticate in routine eye examination in the occurrence of MGD.	27779170
Airway structure	Altered Intercellular Communication	The preservation of EPIs may have a therapeutic benefit in intractable airway inflammation, such as eosinophilic CRS.	27779422
Inflammation, Endotoxemia, Irritable Bowel Syndrome	Altered Intercellular Communication	Systemic symptoms in irritable bowel syndrome: An investigative study on the role of enterocyte disintegrity, endotoxemia and inflammation.	27779674
Inflammation, Traumatic injury	Altered Intercellular Communication	Bone marrow (BM) residing stem cells are mobilized from their BM niches into peripheral blood (PB) in several pathological situations including tissue organ injury and systemic inflammation.	27779706
Inflammation, Data types - Address	Altered Intercellular Communication	Inflammation occurs in the brains of patients with AD, and is critical for disease progression.	27779711
HD Term Type	Altered Intercellular Communication	Low lean body mass (LBM) is an indicator of malnutrition inflammation syndrome, which is common in hemodialysis (HD) patients.	27780214
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	These results show that microbial signals enhance the TGFb-activating ability of human DC via regulation of integrin avb8 expression, and that intestinal inflammation may drive this pathway in patients with IBD.	27782111
Inflammatory Bowel Diseases	Altered Intercellular Communication	Expression was significantly upregulated on intestinal DC from IBD patients, indicating that inflammatory signals may upregulate expression of this key TGFb-activating molecule.	27782111
Pneumonitis, Pneumonia	Altered Intercellular Communication	YKL-40, CCL18 and SP-D levels were higher in patients with more severe pneumonia, possibly reflecting the extent of pulmonary inflammation.	27782361
Intraocular inflammation, Uveitis	Altered Intercellular Communication	Clinical Patterns and Causes of Intraocular Inflammation in a Uveitis Patient Cohort from Egypt.	27782772
Intraocular inflammation, Uveitis	Altered Intercellular Communication	To analyze the patterns and causes of intraocular inflammation in patients attending uveitis referral clinics in Egypt.	27782772
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Diagnostic evaluation of appendiceal orifice inflammation in ulcerative colitis.	27782893
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	To evaluate the diagnostic significance of appendiceal orifice inflammation (AOI) in ulcerative colitis (UC) patients.	27782893
Pain Distress Question, Inflammation	Altered Intercellular Communication	Overall, conditions characterised by pain and inflammation tended to show stronger associations with MDE.	27784343
Inflammation, 3,4-methylenedioxyethamphetamine, Pain Distress Question	Altered Intercellular Communication	The prevalence of MDE is elevated in association with most chronic conditions, but especially those characterised by inflammation and pain.	27784343
Inflammation, Cartilage damage	Altered Intercellular Communication	In the AIA model, cartilage damage and inflammation were also reduced in CD9-/- mice.	27784871
Inflammation, Infection	Altered Intercellular Communication	Cholinergic PET imaging in infections and inflammation using 11C-donepezil and 18F-FEOBV.	27785538
Inflammation, Carcinoma of lung, Infection	Altered Intercellular Communication	Finally, we present initial data from human patients with infections, inflammation, and renal and lung cancer.	27785538
Inflammation, Non-Small Cell Lung Carcinoma, Pneumonia	Altered Intercellular Communication	In humans, very high 11C-donepezil uptake was seen in a lobar pneumonia and in peri-tumoral inflammation surrounding a non-small cell lung carcinoma, markedly superseding the 18F-FDG uptake in the inflammation.	27785538
Inflammation	Altered Intercellular Communication	Preliminary data in humans strongly suggest that 11C-donepezil can exhibit more intense accumulation than 18F-FDG at sites of chronic inflammation.	27785538
Inflammation, Infection, Inflammatory disorder	Altered Intercellular Communication	Cholinergic PET imaging may therefore have potential applications for basic research into cholinergic mechanisms of immune modulation, but also clinical applications for diagnosing infections, inflammatory disorders, and cancer inflammation.	27785538
Inflammation, Primary malignant neoplasm, Traumatic injury, Neoplasms	Altered Intercellular Communication	Recent studies suggest that systemic inflammation induced by surgical trauma can accelerate the adhesion of circulating tumor cells to the vascular endothelium of distant organs, resulting in early cancer recurrence.	27785660
Inflammation, Disease	Altered Intercellular Communication	The inflammation markers and RA disease activity were also assessed.	27785938
Inflammation, Synovitis	Altered Intercellular Communication	The detection of synovitis by imaging was more important than disease activity and inflammation markers for assessing the progression of shoulder joint destruction.	27785938
Psoriatic Juvenile Idiopathic Arthritis, Inflammation, Psoriasis	Altered Intercellular Communication	Irisin might be a marker of inflammation in psoriatic patients, but may not be a reliable indicator of metabolic conditions, severity of psoriasis nor efficacy of antipsoriatic treatment.	27786588
Inflammatory Bowel Diseases, Crohn Disease, Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Crohn's disease and ulcerative colitis, collectively known as inflammatory bowel disease (IBD), are characterized by chronic inflammation of the gastrointestinal tract (1).	27787492
Inflammation, Primary malignant neoplasm, Acidosis, Fever, CTCAE	Altered Intercellular Communication	These results suggest that acting together fever and local acidosis might drive the differentiation of neutrophils into a profile able to promote both cancer progression and tissue repair during the late phase of inflammation, two processes that are strongly dependent on the local production of angiogenic factors by infiltrating immune cells.	27787523
selenium, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	SE could estimate advanced liver fibrosis without influence of liver inflammation unlike other serological liver fibrosis markers.	27787686
Inflammation, Psoriasis	Altered Intercellular Communication	Increased global arterial and subcutaneous adipose tissue inflammation in patients with moderate-to-severe psoriasis.	27787888
Inflammation, Psoriasis, Cardiovascular Diseases	Altered Intercellular Communication	Psoriasis is associated with cardiovascular disease; it has been proposed that increased cardiovascular risk is caused by low-grade systemic inflammation involving organs and tissues other than the skin and joints.	27787888
vascular inflammations, Psoriasis	Altered Intercellular Communication	To investigate signs of vascular inflammation in untreated patients with moderate-to-severe psoriasis assessed by 18 F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography.	27787888
Inflammation, Psoriasis	Altered Intercellular Communication	Arterial inflammation was increased in patients with psoriasis vs. controls (mean +- SD whole vessel TBRmax 246 +- 031 vs. 209 +- 036; P = 0*005).	27787888
Inflammation, Psoriasis	Altered Intercellular Communication	Global arterial inflammation and subcutaneous inflammation were significantly increased in patients with moderate-to-severe psoriasis compared with controls.	27787888
Inflammation, Fibrosis Assessment, Fatty degeneration, Chronic liver disease	Altered Intercellular Communication	Hepatic Fibrosis, Inflammation, and Steatosis: Influence on the MR Viscoelastic and Diffusion Parameters in Patients with Chronic Liver Disease.	27788034
Inflammation, Fibrosis Assessment, Fatty degeneration, Chronic liver disease	Altered Intercellular Communication	Purpose To determine the relationship of liver fibrosis, inflammation, and steatosis with the magnetic resonance (MR) viscoelastic and diffusion parameters in patients with chronic liver disease and to compare the diagnostic accuracy of the imaging parameters in staging liver fibrosis.	27788034
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Fibrosis, inflammation, and steatosis were assessed with the METAVIR and steatosis, activity, and fibrosis (or SAF) scoring systems.	27788034
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Spearman correlation and multiple regression analyses were performed to determine the relationship between liver fibrosis, inflammation, steatosis, and alanine aminotransferase (ALT) levels and viscoelastic and diffusion parameters.	27788034
Inflammation	Altered Intercellular Communication	Inflammation and ALT level were not associated with the viscoelastic or diffusion parameters.	27788034
Inflammation, Heart failure	Altered Intercellular Communication	Heart failure can be associated with inflammation but it is unclear if inflammation is directly related to hemodynamic worsening or is an independent pathway.	27788390
Inflammation, Heart failure, F8 wt Allele, Congestive heart failure	Altered Intercellular Communication	Our aim was to investigate inflammation and mechanical stress using serial measurements of biomarkers in acute and chronic heart failure with reduced ejection fraction (AHF and CHF).	27788390
Inflammation, Traumatic injury	Altered Intercellular Communication	Reg family proteins (Reg1A, 1B, 3A/G, 4) are a group of calcium-dependent lectins that promote islet growth in response to inflammation and/or injuries.	27788482
Inflammation, Retinal Artery Occlusion, Susac Syndrome, hearing impairment, Encephalopathy, CTCAE 5.0	Altered Intercellular Communication	Susac's syndrome is characterized by inflammation and occlusion of pre-capillary arterioles with the clinical triad of branch retinal artery occlusion (BRAO), encephalopathy and hearing loss.	27788613
Idiopathic disease, Necrotizing, Sialometaplasia, Necrotizing	Altered Intercellular Communication	Necrotising sialometaplasia is a benign, necrotising, self-healing inflammatory condition categorised as idiopathic disease of salivary glands.	27789544
Inflammation	Altered Intercellular Communication	Histological examination was consistent with acute inflammation of the appendiceal stump.	27789546
Fracture, Myositis	Altered Intercellular Communication	Together, our pilot data support that exercise training alters skeletal muscle inflammation and ceramide metabolism associated with TLR signaling in older adults recovering from hip fracture surgery and may be related to improvements in muscle function recovery.	27789770
Inflammation, Fracture	Altered Intercellular Communication	These pilot data demonstrate that 3 mo of exercise training in older adults recovering from hip fracture surgery was able to mitigate skeletal muscle gene expression related to inflammation and ceramide metabolism while also improving surgical limb lean tissue, strength, and physical function.	27789770
Inflammation	Altered Intercellular Communication	Oxidative/carbonyl stress via protein carbonylation is an important factor in causing inflammation and DNA damage.	27791204
Inflammation, Disease	Altered Intercellular Communication	This results in stress-induced premature senescence (a state of irreversible growth arrest which re-enforces chronic inflammation) in gingival epithelium, which may contribute to the pathogenesis of oral diseases.	27791204
Inflammation, Communicable Diseases, Glaucoma, CTCAE, Optic Atrophy, Lens dislocation, Diabetic Retinopathy, Traumatic injury, Corneal Diseases, Exfoliation Syndrome	Altered Intercellular Communication	Exclusion criteria were history of ocular trauma or intraocular surgery, any sign of inflammation or infection, pseudoexfoliation syndrome, glaucoma, optic atrophy, diabetic retinopathy, lens dislocation, cataracta intumescens, cataracta matura, and corneal diseases.	27791246
Atherosclerotic lesion	Altered Intercellular Communication	Several studies have indicated that EVs may play a potential role in cell-to-cell communication between macrophage foam cells and vascular smooth muscle cells (VSMCs) in atherosclerotic lesion.	27792649
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Cadmium exposure is associated with soluble urokinase plasminogen activator receptor, a circulating marker of inflammation and future cardiovascular disease.	27792942
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Cadmium increases the risk of cardiovascular diseases, and experimental studies show that it induces inflammation.	27792942
Inflammation, atherosclerotic	Altered Intercellular Communication	Soluble urokinase-type plasminogen activator receptor (suPAR) is an emerging biomarker for cardiovascular events related to inflammation and atherosclerotic plaques.	27792942
Inflammation, Lymphohistiocytosis, Hemophagocytic, Hematological Disease	Altered Intercellular Communication	Hemophagocytic lymphohistiocytosis (HLH) is a life threatening hematological disorder associated with severe systemic inflammation caused by an uncontrolled and ineffective immune response resulting in cytokine storm.	27793118
Inflammation, Lymphoproliferative Disorders	Altered Intercellular Communication	The presence of foreign material can cause chronic inflammation that could be the stimulus for the development of a lymphoproliferative disorder.	27793489
Inflammation, Saint Lucia	Altered Intercellular Communication	Inflammation should not be targeted systematically in all patients with LC.	27793775
Inflammation, Renal tubular disorder, Atherosclerosis, MPV17 gene, Heart failure	Altered Intercellular Communication	Conclusions We discovered and replicated associations between ACR and five cardiovascular proteins involved in tubular injury, atherosclerosis, endothelial function, heart failure, inflammation, glomerulosclerosis and podocyte injury.	27794105
Rupture, Acute abdominal pain, Inflammation	Altered Intercellular Communication	The rupture occurred on the right lateral wall of the ileocecal pouch in 4 out of 5 cases and led to acute abdominal pain and inflammation.	27794573
vascular inflammations	Altered Intercellular Communication	In recent years, platelets are known to have a large variety of functions in many pathophysiological processes and their interaction with endothelial cells and leukocytes is known to play an important role in the pathophysiology of vascular inflammation.	27795782
Inflammation, physical illness, Depression, CTCAE	Altered Intercellular Communication	There is evidence that inflammation may play a role in the association between physical illness and depression.	27796262
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Our aim was to compare the impact of chronic medical conditions on incidence of depression and to examine if risk of depression varies in terms of the presence and degree of inflammation.	27796262
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Inflammation may be part of the pathway by which chronic physical illness leads to depression.	27796262
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Future studies should examine the role of inflammation in the prevention and management of depression.	27796262
Inflammation, Thoracic aorta calcification, Cardiovascular Diseases	Altered Intercellular Communication	Thoracic aorta calcification but not inflammation is associated with increased cardiovascular disease risk: results of the CAMONA study.	27796543
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Vascular calcification, Cardiovascular Diseases	Altered Intercellular Communication	Arterial inflammation and vascular calcification are regarded as early prognostic markers of cardiovascular disease (CVD).	27796543
Vascular calcification, Arteritis	Altered Intercellular Communication	Our findings indicate that an unfavourable CVD risk profile is associated with marked increases in vascular calcification metabolism and vascular calcium burden of the thoracic aorta, but not with arterial inflammation.	27796543
Inflammation, Cardiovascular Diseases, Collagen Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Obesity	Altered Intercellular Communication	In the general population, low-grade inflammation of adipose tissue accompanies obesity and contributes to cardiovascular disease (CVD) development, but the implication of this tissue in rheumatic disease pathology is unclear.	27796618
Inflammation, Refractory anemias, Degenerative polyarthritis, Rheumatoid Arthritis, Comorbidity	Altered Intercellular Communication	Therefore, we characterized the secretory activity of subcutaneous abdominal adipose tissue (SAAT) of females with rheumatoid arthritis (RA) and osteoarthritis (OA) and searched for its relationship with intensity of systemic inflammation, body composition and comorbidity.	27796618
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	In OA, secretion of leptin and HGF positively, while adiponectin inversely, correlated with systemic inflammation markers, and the release of MIF was an independent risk factor for CVD.	27796618
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	This study reveals differences between RA and OA patients in SAAT secretory activity and suggests its different clinical impact in these diseases, characterized by high- and low-grade systemic inflammation, respectively.	27796618
Inflammation, Refractory anemias, Degenerative polyarthritis, Amyloidosis, Cachexia	Altered Intercellular Communication	In RA, SAAT may directly or via an effect on body composition contribute to amyloidosis, cachexia or CVD co-occurring, while in OA SAAT-derived adipocytokines may rather regulate intensity of systemic inflammation and redound to CVD emergence.	27796618
Sexually Transmitted Diseases, Sense of Inadequacy Scale	Altered Intercellular Communication	Sexually transmitted disease (STD), hormonal usage, previous cryotherapy and smears collected by staff were associated with inadequacy of TZ.	27797219
Hodgkin Disease	Altered Intercellular Communication	Hepatitis C Virus Associations with Non Hodgkin's Lymphoma: Insights on Inflammation/Angiogenesis and CD Markers.	27797254
Lymphoma, Non-Hodgkin, Communicable Diseases, Hepatitis C, RTEL1 gene	Altered Intercellular Communication	We aimed to investigate any association between hepatitis C virus (HCV) infection and non-Hodgkin's lymphoma (NHL) in the view of cytokines that control inflammation/angiogenesis and their correlation with certain CD markers.	27797254
Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Fatty degeneration, Fatty Liver Disease	Altered Intercellular Communication	Chemerin mRNA did not correlate with steatosis and was negatively associated with inflammation, fibrosis and nonalcoholic steatohepatitis (NASH) score.	27797398
Inflammation, Arteriovenous fistula, Restenosis, Atherosclerosis	Altered Intercellular Communication	Inflammation is relevant in restenosis of atherosclerotic vascular diseases, but its role in dialysis arteriovenous fistula remains unknown.	27797894
Inflammation, Hypoxia	Altered Intercellular Communication	Although tissue hypoxia and inflammation are recognized as central drivers of vessel growth, relatively little is known about the process that bridges the two.	27797960
Inflammation, ovarian neoplasm, Neoplasms	Altered Intercellular Communication	Patients with low glycerophospholipids presented with more systemic inflammation (C-reactive protein and fibrinogen negatively and albumin positively correlated) but less adaptive immune cell tumor infiltration (lower tumor and immune cell PD-L1 expression), less oxygenic respiration and increased triglyceride biosynthesis in tumor cells, and lower histone expressions, correlating with higher numbers of expressed genes and more transcriptional noise, a putative neo-pluripotent tumor cell phenotype.Conclusions: Low serum phospholipids and essential amino acids are correlated with worse outcome in ovarian cancer, accompanied by a specific tumor cell phenotype.	27797973
Tumor necrosis	Altered Intercellular Communication	Plasma Inflammation Markers of the Tumor Necrosis Factor Pathway but Not C-Reactive Protein Are Associated with Processed Meat and Unprocessed Red Meat Consumption in Bavarian Adults.	27798340
Inflammation	Altered Intercellular Communication	Further research on the role of TNF pathway markers in chronic inflammation is warranted.	27798340
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Increased levels of TNF-a and IL6 are associated with inflammation and cardiovascular disease among patients with normal kidney function.	27798514
Axonal degeneration, Inflammation, POEMS Syndrome, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	Altered Intercellular Communication	We hypothesized that nerve biopsies from patients with POEMS syndrome would have more small vessels and axonal degeneration but less inflammation than CIDP.We performed a retrospective analysis of nerve biopsies performed on "classic" CIDP and POEMS cases.	27799073
Axonal degeneration, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating, Inflammation	Altered Intercellular Communication	POEMS syndrome demonstrates more axonal degeneration and epineurial neovascularization whereas CIDP has greater endoneurial inflammation and onion-bulb formation.	27799073
Inflammation, Autonomic nervous system disorders	Altered Intercellular Communication	It has been reported that sleep deprivation is associated with cardiac autonomic disorder, inflammation, and oxidative stress.	27799236
Inflammation, HIV Infections	Altered Intercellular Communication	Inflammation, Immune Activation, Immunosenescence, and Hormonal Biomarkers in the Frailty-Related Phenotype of Men With or at Risk for HIV Infection.	27799351
Hormone abnormality, Inflammation, HIV	Altered Intercellular Communication	The extent to which inflammation, immune activation/immunosenescence, and hormonal abnormalities are driven by human immunodeficiency virus (HIV) or frailty is not clear.	27799351
Inflammation, HIV Infections	Altered Intercellular Communication	Inflammation, Immune Activation, Immunosenescence, and Hormonal Biomarkers in the Frailty-Related Phenotype of Men With or at Risk for HIV Infection.	27799351
Hormone abnormality, Inflammation, HIV	Altered Intercellular Communication	The extent to which inflammation, immune activation/immunosenescence, and hormonal abnormalities are driven by human immunodeficiency virus (HIV) or frailty is not clear.	27799351
Orbital Pseudotumor	Altered Intercellular Communication	Orbital biopsy of nonspecific orbital inflammation, commonly referred to as "orbital pseudotumor," typically shows a combination of polyclonal lymphocytes, plasmocytes, leukocytes, macrophages, and variable degrees of collagen deposition.	27799649
Mucocutaneous leishmaniasis, Orbital Pseudotumor	Altered Intercellular Communication	Herein, we report a patient with a positive history of mucocutaneous leishmaniasis who presented with an orbital mass with a histological profile of idiopathic orbital inflammation.	27799649
Leishmania viannia, Orbital Pseudotumor	Altered Intercellular Communication	Immunohistochemical and molecular analysis of the orbital specimens demonstrated that the orbital inflammation was associated with the presence of antigens of Leishmania braziliensis and DNA from the parasite.	27799649
ARCN1 gene, Toxic effect, Disease	Altered Intercellular Communication	Due to the low toxicity and known compatibility of the substance, an inhalative application as an intervention strategy for humans suffering from diseases caused by neutrophilic inflammation, like COPD, had been suggested.	27799756
ARCN1 gene, Upper Respiratory Infections	Altered Intercellular Communication	The results indicate that there is a link present between upper and lower respiratory inflammation in NIR and COPD.	27799760
Inflammation	Altered Intercellular Communication	Neutrophil-lymphocyte ratio greater than 5 at diagnosis represented systemic inflammation.	27800646
Inflammation, Necrosis	Altered Intercellular Communication	The vascular media showed scant lymphocytic inflammation without necrosis.	27801754
Inflammation, Uterine Fibroids	Altered Intercellular Communication	Vessels outside of the leiomyoma showed neither fibrinoid changes nor inflammation.	27801754
Anxiety, CTCAE 3.0, Prostate Cancer Outcomes Study, Mood Disorders, Depression, CTCAE	Altered Intercellular Communication	Also, decrease in neurotransmitters, mainly NE, serotonin and dopamine (DA) attributes to mood disorders like depression and anxiety in PCOS.	27802175
Inflammation	Altered Intercellular Communication	We identified that oxygen exchange and CRP, a marker of acute inflammation, were the most important predictors of safe discharge.	27803369
Inflammation, Myocardial, Cardiac sarcoidosis	Altered Intercellular Communication	Regional myocardial damage and active inflammation in patients with cardiac sarcoidosis detected by non-invasive multi-modal imaging.	27804054
Myocarditis	Altered Intercellular Communication	Regions with a higher SUVmax indicating active myocardial inflammation were mainly located in areas with LGE, where BMIPP and TL mismatches were evident in patients with CS.	27804054
Inflammation, Coronary heart disease	Altered Intercellular Communication	The development of several life-long diseases, such as coronary heart disease, is affected by low-grade systemic inflammation.	27804311
Typhlitis, Malignant Neoplasms	Altered Intercellular Communication	These PET/CT findings are most consistent with methotrexate-induced thecal inflammation, which needs to be distinguished from intrathecal malignancy.	27805919
Aneuploidy, Inflammation, FBN2 wt Allele	Altered Intercellular Communication	Advanced ERC findings, male gender, suspicious BC, aneuploidy in flow cytometry, inflammation, and elevation of ALP, bilirubin, ALT, AST, GGT, CEA and CA19-9 represented significant risk factors for CCA in univariate analysis.	27806633
Bile Duct Diseases, Inflammation, FBN2 wt Allele, Elevated liver enzymes	Altered Intercellular Communication	PSC patients with advanced bile duct disease and elevated liver enzymes, CEA or CA19-9, inflammation or suspicious BC are most likely to develop CCA.	27806633
Inflammation, Dysplasia, Primary malignant neoplasm	Altered Intercellular Communication	We identified four potential biomarkers from an inflammation (IL1b)-dependent mouse model of Barrett esophagus and tested them in 189 patients with Barrett esophagus with and without high-grade dysplasia (HGD)/early cancer (T1).	27807078
Stomach Carcinoma	Altered Intercellular Communication	The Preoperative Frailty Versus Inflammation-Based Prognostic Score: Which is Better as an Objective Predictor for Gastric Cancer Patients 80 Years and Older?	27807726
Inflammation	Altered Intercellular Communication	Activin A is a pleiotropic cytokine holding a fundamental role in inflammation and tissue remodelling.	27807906
Inflammation	Altered Intercellular Communication	The inflammation of neurons causes release of various inflammatory mediators (IFNs, EGF, IL5, IL6, HGF, LIF and BMP2).	27808010
airway disease, Inflammation, Asthma	Altered Intercellular Communication	We conclude that variations in ASM ER expression profiles occur with inflammation and that ER variants could contribute to estrogen signaling in airway diseases such as asthma.	27808402
Kidney Failure, Chronic, Inflammation, Dysautonomia, Familial	Altered Intercellular Communication	Association between autonomic nervous dysfunction and cellular inflammation in end-stage renal disease.	27809785
HD Term Type, Inflammation	Altered Intercellular Communication	We intended to confirm a role of autonomous dysregulation for inflammation in HD patients.	27809785
Inflammation	Altered Intercellular Communication	Patients suffered from chronic inflammation (CRP 9.4 [12.9] mg/l, controls 1.6 [2.4] mg/l, p < 0.001) and expanded proinflammatory monocyte subpopulations (CD14++/CD16+ cells: patients 41 [27]/ml, controls 24 [18]/ml, p < 0.01).	27809785
Inflammation, Muscle damage	Altered Intercellular Communication	Independent predictors of elevation in the levels of markers of inflammation and muscle damage were determined by a multivariate linear regression model.	27810151
Inflammation	Altered Intercellular Communication	In the absence of cerebrospinal fluid (CSF) abnormality, systemic inflammation did not affect the CSF/serum albumin ratio.	27810376
Inflammation, Abnormality of the cerebrospinal fluid	Altered Intercellular Communication	When CSF abnormality was present, systemic inflammation significantly predicted the CSF/serum albumin ratio.	27810376
Inflammation	Altered Intercellular Communication	In conclusion, the diseased BBB has an increased susceptibility to systemic inflammation.	27810376
Bladder polyp, Inflammation, Schistosomiasis	Altered Intercellular Communication	Bladder polyps due to schistosomiasis represent a rare condition in developed countries and have to be ruled out in the case of any intense unexplained inflammation.	27810520
Inflammation, diabetic	Altered Intercellular Communication	The mitochondria-targeted antioxidant MitoQ modulates oxidative stress, inflammation and leukocyte-endothelium interactions in leukocytes isolated from type 2 diabetic patients.	27810734
Inflammation	Altered Intercellular Communication	Clinical significance of GCF sIL-6R and calprotectin to evaluate the periodontal inflammation.	27810997
Inflammation	Altered Intercellular Communication	Conclusions Both gingival crevicular fluid sIL-6R and calprotectin concentrations are significant biomarkers in the evaluation of periodontal inflammation.	27810997
Inflammation, S100A4 protein, human	Altered Intercellular Communication	IL-1b is an essential factor of inflammation initiation, and it also promotes malignant transformation, indicating its tumorigenic property.	27811377
Inflammation, Cardiomyopathies	Altered Intercellular Communication	Macrophage migration inhibitory factor (MIF) promotes inflammation and is an important factor in uremic cardiomyopathy.	27811451
methyldopa, Inflammation	Altered Intercellular Communication	Although the exact pathogenic mechanism of AMD is still unknown, clinical observations such as the high accumulation of oxidative products and macrophages in retina suggest the importance of oxidative stress and inflammation in AMD.	27812755
Inflammation, Tacca leontopetaloides, Cerebrovascular accident	Altered Intercellular Communication	Background History of stroke symptoms in the absence of prior diagnosed stroke or transient ischemic attack (TIA) is associated with future stroke risk, as are biomarkers of inflammation, cardiac function and hemostasis.	27813265
Rheumatoid Arthritis, Fibrosis Assessment, Myocarditis	Altered Intercellular Communication	Magnetic Resonance Imaging-Detected Myocardial Inflammation and Fibrosis in Rheumatoid Arthritis: Associations With Disease Characteristics and N-Terminal Pro-Brain Natriuretic Peptide Levels.	27813364
Disease	Altered Intercellular Communication	These data suggest that cardiac MRI findings indicating myocardial inflammation/fibrosis are correlated with RA disease activity and alterations in myocardial structure known to precede clinical HF.	27813364
Pancreatitis, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8	Altered Intercellular Communication	PDG cell replication was increased in T1D (6.3% +- 1.6% vs 0.6% +- 0.1%, P < 0.001, T1D vs nondiabetic), most prominently in association with pancreatic inflammation.	27813705
Inflammation, Pancreatitis due to pancreatic duct obstruction, Intraductal Hyperplasia, Atrophy of pancreas, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8	Altered Intercellular Communication	The PDG compartment is activated in T1D consistent with a response to ongoing inflammation, and via resulting ductal hyperplasia may contribute to local obstructive pancreatitis and eventual pancreatic atrophy characteristic of T1D.	27813705
Inflammation, Neoplasms	Altered Intercellular Communication	Other biomarkers reflect the inflammation and tumor burden like high-sensitivity C-reactive protein(hs-CRP) and urine free light chain were also detected.	27814274
Multiple Myeloma, Inflammation, Injury of kidney, Neoplasms	Altered Intercellular Communication	And it could be considered an independent predictor of renal injury from multiple myeloma reflecting active kidney damage, tumor burden, and inflammation.	27814274
Inflammation, Endothelial dysfunction, Atherosclerosis	Altered Intercellular Communication	Human cartilage glycoprotein-39 (YKL-40) has been suggested to be a new marker of inflammation, atherosclerosis, and endothelial dysfunction.	27815265
Inflammation, Uveitis	Altered Intercellular Communication	The construct "uveitis inflammatory activity" was defined as any intraocular inflammation that included external structures (cornea) in addition to uvea.	27815703
Inflammation, Papilledema, Edema, Vitreous haze, Hypopyon, vascular inflammations	Altered Intercellular Communication	Seven domains and 15 items were identified: best-corrected visual acuity, inflammation of the anterior chamber (anterior chamber cells, hypopyon, the presence of fibrin, active posterior keratic precipitates and iris nodules), intraocular pressure, inflammation of the vitreous cavity (vitreous haze, snowballs and snowbanks), central macular edema, inflammation of the posterior pole (the presence and number of choroidal/retinal lesions, vascular inflammation and papillitis), and global assessment from both (patient and physician).	27815703
Delirium, Inflammation, Ischemic stroke	Altered Intercellular Communication	Our aim was to determine whether there is an entity relationship between delirium, inflammation and acute ischemic stroke (AIS).	27816188
Inflammation	Altered Intercellular Communication	As early as 1-week post-ischemia, an increased number of newborn cells in the subventricular zone and a reduced number of activated microglial cells in the peri-infarct area were observed in the UCB-PL group, suggesting that enhanced neurogenesis and/or the suppression of inflammation may have contributed to functional protection/recovery.	27816964
Inflammation, Neoplasms	Altered Intercellular Communication	Late compared with early imaging was better able to distinguish between malignant and benign tissue [W3, SUVmean: tumour vs. BPH 2.5 vs. 2.0 (p<0.001), tumour vs. inflammation 2.5 vs. 1.7 (p<0.001), tumour vs. healthy tissue 2.5 vs. 2.0 (p<0.001); W1, SUVmean: tumour vs. BPH 3.1 vs. 3.1 (p=0.771), tumour vs inflammation 3.1 vs. 2.2 (p=0.021), tumour vs. healthy tissue 3.1 vs. 2.5 (p<0.001)] as well as between high-grade and low/intermediate-grade tumours (W3, SUVmean: 2.6 vs. 2.1 (p=0.040); W1, SUVmean: 3.1 vs. 2.8 (p=0.173)).	27817158
Inflammation, Neoplastic Cell Transformation	Altered Intercellular Communication	Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression.	27818180
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Decreased preoperative serum 25-Hydroxyvitamin D levels in colorectal cancer are associated with systemic inflammation and serrated morphology.	27819306
Inflammation, Atherosclerosis, Communicable Diseases, Chlamydia, HIV	Altered Intercellular Communication	In the last decade, several infectious agents rather than any single pathogen, including Chlamydia pneumoniae and human immunodeficiency virus (HIV), have been shown to contribute to the development of atherosclerosis and subsequent cardiovascular events by inducing systemic inflammation and/or acting directly on the vascular wall.	27819396
Uremia, Inflammation, Malnutrition, Infection	Altered Intercellular Communication	Haemodialysis patients are at greater risk of infections than individuals not on dialysis due to their immunosuppressive state caused by several factors (uraemia, vascular access, inflammation, malnutrition).	27819399
Inflammation, Schizophrenia	Altered Intercellular Communication	Since growing evidence suggests a significant role of chronic low-grade inflammation in the physiopathology of schizophrenia, we have hypothesized that functional genetic variant of the IFN gamma (IFN-g; +874A/T; rs2430561) gene may be involved in the predisposition to schizophrenia.	27819519
Inflammation	Altered Intercellular Communication	18F-FDG Imaging of Chronic Inflammation Associated With Promontofixation of the Uterus.	27819855
Inflammation	Altered Intercellular Communication	Promontofixation can be associated with complications due to chronic inflammation.	27819855
Inflammation	Altered Intercellular Communication	F-FDG-PET may diagnose chronic inflammation of the mesh.	27819855
Trachoma , Perifolliculitis	Altered Intercellular Communication	To complete the baseline trachoma map in Oromia, Ethiopia, by determining prevalences of trichiasis and trachomatous inflammation - follicular (TF) at evaluation unit (EU) level, covering all districts (woredas) without current prevalence data or active control programs, and to identify factors associated with disease.	27820657
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	It is assosiciated with two step hit scenario; the first step is fat accumulationin liver and in the second step inflammation and fibrosis are the major compenents.	27821024
Allergic sensitization, Inflammation, "Extra-osseous Ewings sarcoma	Altered Intercellular Communication	Although its pathogenesis remains poorly understood, there is strong evidence that the eosinophilic inflammation in EoE is primarily triggered by immune dysregulation secondary to allergic sensitization to dietary or aero-allergens.	27821174
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Serum HDL-c levels were the major determinant of the associations between serum hs-CRP levels and MetS and the key link between inflammation and MetS.	27822025
Refractory anemias, Rheumatoid Arthritis, destruction joint, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) appears as inflammation of synovial tissue and joint destruction.	27822475
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Inflammation plays a crucial role in the progression of chronic heart failure (CHF).	27822484
Colorectal Carcinoma	Altered Intercellular Communication	A Postoperative Systemic Inflammation Score Predicts Short- and Long-Term Outcomes in Patients Undergoing Surgery for Colorectal Cancer.	27822634
Systemic Inflammatory Response Syndrome, Communicable Diseases, Inflammation	Altered Intercellular Communication	Our aim was to compare the area under the receiver operating curve (AUROC), sensitivity, specificity, and likelihood ratios of qSOFA vs. systemic inflammation response syndrome (SIRS) in predicting in-hospital mortality among emergency department (ED) patients with suspected infection admitted to intensive care units (ICUs).	27823893
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Systemic inflammation and immune responses are reported to be associated with progressive prostate cancer.	27823973
Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	To investigate the association between C-reactive protein/albumin ratio (CAR), an inflammation-based prognostic score, and clinicopathological factors, as well as its association with long-term outcomes in patients with operable non-small cell lung cancer (NSCLC).	27823974
Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	We aimed to search new probiotic candidates for inflammatory bowel disease through translational research by analysis of ulcerative colitis (UC) patients' intestinal microbiota and clarify the effects of them on inflammation.	27824645
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	We analyzed the association of F. saccharivorans to UC patients' activity and inflammation for the first time.	27824645
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	F. saccharivorans decreased in correlation to UC activity and suppresses intestinal inflammation.	27824645
Inflammation, HIV Infections	Altered Intercellular Communication	Do Biomarkers of Inflammation, Monocyte Activation, and Altered Coagulation Explain Excess Mortality Between HIV Infected and Uninfected People?	27824677
Inflammation, HIV Infections	Altered Intercellular Communication	HIV infection and biomarkers of inflammation [measured by interleukin-6 (IL-6)], monocyte activation [soluble CD14 (sCD14)], and coagulation (D-dimer) are associated with morbidity and mortality.	27824677
Inflammation, Intestinal Diseases	Altered Intercellular Communication	Environmental enteropathy (EE) is a poorly understood condition that refers to chronic alterations in intestinal permeability, absorption, and inflammation, which mainly affects young children in resource-limited settings.	27824883
Inflammation, Cocaine-Related Disorders	Altered Intercellular Communication	Elevated levels of C-reactive protein (CRP, determined by a high-sensitivity assay) indicate low-grade inflammation which is implicated in many age-related disorders.	27824951
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	inflammation), while ten had polyps/adenomas and seven a hitherto undiagnosed colorectal cancer.	27824964
Communicable Diseases, Unknown (origin) (qualifier value), Pericarditis, CTCAE, Inflammation	Altered Intercellular Communication	Historically the most common causes of pericarditis necessitating pericardiectomy are infection, radiation, idiopathic causes, and inflammation.	27825685
Inflammation	Altered Intercellular Communication	Patients with moderate to severe plaque-type psoriasis had active systemic inflammation, which was demonstrated by increased levels of C-reactive protein.	27828628
Inflammation, Skin lesion	Altered Intercellular Communication	Phototherapy healed the psoriatic skin lesions and reduced inflammation, while decreasing C-reactive protein levels.	27828628
Neoplasms	Altered Intercellular Communication	Nine courses resulted in a total radiological tumour shrinkage and hormonal normalisation.	27828691
Pheochromocytoma, Inflammation, Swelling, Orbital Fractures	Altered Intercellular Communication	We report on a 68-year-old survivor of pheochromocytoma multisystem crisis, whose clinical course was triggered inadvertently by a short innocuous course of oral dexamethasone to suppress inflammation and swelling after a left orbital floor fracture repair.	27828782
Inflammation	Altered Intercellular Communication	Red cell distribution width (RDW) is linked to cardiovascular risk in the general population, an association that might be driven by inflammation.	27828877
Inflammatory infiltrate, Thyroid associated opthalmopathies, Myositis, CTCAE 5.0, Orbital Pseudotumor, Vascular anomaly, Central neuroblastoma	Altered Intercellular Communication	An evaluation for thyroid eye disease, idiopathic orbital inflammation, myositis, inflammatory and neoplastic infiltration of the muscle, vascular anomalies, and metastatic neuroblastoma was unrevealing.	27828922
Inflammation, Fibrosis Assessment, Infiltration	Altered Intercellular Communication	Biopsy of the muscle revealed normal architecture with an absence of inflammation, infiltration, or fibrosis.	27828922
Sepsis, Inflammation	Altered Intercellular Communication	Epidural block decreases inflammation and oxidative stress in experimental models of sepsis as well as after surgery.	27829181
Inflammation, Coronary heart disease	Altered Intercellular Communication	These findings suggest that, in the context of severe adversity, a trait-like tendency towards greater relative right prefrontal activity may predispose to low-grade inflammation, a risk factor for conditions with inflammatory underpinnings such as coronary heart disease.	27829190
Intraocular inflammation, Irritation, Traumatic aniridia	Altered Intercellular Communication	In this case report, we describe the case of a 49 year old, male construction worker with traumatic aniridia who experienced chronic, recurrent low-grade intraocular inflammation and irritation for months after implantation of the Ophtec 311 prosthetic iris.	27829389
Intraocular inflammation, Endophthalmitis, CTCAE, Traumatic aniridia	Altered Intercellular Communication	Chronic, post-operative endophthalmitis may be a difficult to identify in the context of traumatic aniridia and iris prosthesis implantation due to other potential etiologies of chronic intraocular inflammation such as implant-induced chafing.	27829389
Intraocular inflammation, Endophthalmitis, CTCAE	Altered Intercellular Communication	Clinicians should suspect chronic, post-operative endophthalmitis in any case of recurrent, low-grade intraocular inflammation.	27829389
Refractory anemias, Inflammation	Altered Intercellular Communication	In conclusion, YY1 plays a critical role in promoting IL-6 transcription in RA which contribute to the inflammation of RA via stimulation of Th17 differentiation.	27829535
Refractory anemias, Inflammation	Altered Intercellular Communication	Thus, YY1 is likely a key molecule involved in the inflammation process of RA.	27829535
Inflammation, Coronary Artery Disease, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Type 2 diabetes mellitus (T2DM) and coronary artery disease (CAD) are both characterized by chronic low-grade inflammation.	27829708
Hyperglycemia, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Hyperglycaemia inhibits REG3A expression to exacerbate TLR3-mediated skin inflammation in diabetes.	27830702
Inflammation, Injury of integument	Altered Intercellular Communication	Here we show that the antimicrobial protein REG3A controls TLR3-mediated inflammation after skin injury.	27830702
Inflammation	Altered Intercellular Communication	To our knowledge, these findings show for the first time that REG3A can modulate specific cutaneous inflammatory responses and that the decrease in cutaneous REG3A exacerbates inflammation in diabetic skin wounds.	27830702
Airway structure, Asthma	Altered Intercellular Communication	Sphingolipid (SL) metabolites have been suggested to be important inflammatory mediators in airway inflammation and asthma.	27830727
Shock, Inflammation, Chronic prostatitis, Erectile dysfunction	Altered Intercellular Communication	Heat shock protein 9-mediated inflammation reaction in patients with chronic prostatitis with erectile dysfunction.	27831659
Inflammation, Heat-Shock Response, Chronic prostatitis, Erectile dysfunction	Altered Intercellular Communication	To investigate the role of heat shock protein (HSP)-9 on the inflammation reaction present in patients with chronic prostatitis with erectile dysfunction (ED).	27831659
Inflammation, Chronic prostatitis	Altered Intercellular Communication	Furthermore, the IIEF-5 scores in the group A were also significantly higher than those in the group C. The serum levels of HSP-9, CRP, TNF-a, IL-6 and CD3 in the sera of patients with chronic prostatitis with ED were clearly increased, reflecting a high degree of inflammation which may be related to the clinical manifestations in patients with chronic prostatitis and ED.	27831659
Airway structure	Altered Intercellular Communication	Secondary outcomes included measures of oxidative stress and airway inflammation, and pulmonary function tests.	27832073
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Clinical remission in some patients with rheumatoid arthritis (RA) may be associated with ongoing synovial inflammation that is not always detectable on clinical examination or reflected by laboratory tests but can be visualized by musculoskeletal ultrasound.	27832086
Inflammation	Altered Intercellular Communication	Residual synovial inflammation was found in 58-67% of the patients who fulfilled at least one set of clinical remission criteria.	27832086
Inflammation	Altered Intercellular Communication	Calprotectin levels were significantly higher in patients with residual synovial inflammation than in those with ultrasound-defined remission (mean 2.5+-1.3 vs. 1.7+-0.8 mg/mL, p<0.005).	27832086
Inflammation, Congenital Abnormality	Altered Intercellular Communication	We report a case of a 39-year-old man in whom an extensive MRI with fluid-sensitive imaging sequences covering the whole of the scapula was beneficial in diagnosing the inflammation adjacent to the bony deformity, which confirmed the etiology of scapular dyskinesis.	27832291
Inflammation	Altered Intercellular Communication	Furthermore, in a 41-year old man without any anatomical variances, a similar MRI showed inflammation at the subscapular fossa that suggested altered scapular kinematics.	27832291
Inflammation	Altered Intercellular Communication	Fluid-sensitive MR images are important in defining the presence of inflammation, and are beneficial in determining the pathological significance of findings through other diagnostic measures.	27832291
Inflammation, Dysplasia, Stomach Carcinoma, Infection caused by Helicobacter pylori, Bile Reflux, Gastritis, Atrophic, Gastric Ulcer, CTCAE 5, Intestinal metaplasia	Altered Intercellular Communication	The incidence of intestinal metaplasia differed significantly in 17 municipal areas ranging from 16.79 to 38.56% and was positively correlated with the age range of 40-70 years, male gender, gastric ulcer, bile reflux, Helicobacter pylori infection, atrophic gastritis, dysplasia, gastric cancer, degree of chronic and acute inflammation, and gross domestic product per capita (P < 0.01).	27832356
Inflammation, Infection caused by Helicobacter pylori, Bile Reflux, Gastric Ulcer, CTCAE 5, Intestinal metaplasia	Altered Intercellular Communication	This study confirms age, male gender, gastric ulcer, bile reflux, H. pylori infection, severe degree of chronic and acute inflammation to be the risk factors for intestinal metaplasia.	27832356
Inflammation, Hypoxia, Atherosclerosis	Altered Intercellular Communication	CD73 (also known as ecto-5'-nucleotidase) is a key regulator of cell signaling in response to inflammation and hypoxia, and may be important in the development of atherosclerosis.	27832456
Inflammation, Bacterial resistance, Obstruction, Stasis	Altered Intercellular Communication	Obstruction in these patients may lead to bacterial overgrowth with stasis and inflammation of the colon.	27832696
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study.	27832762
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Adults with chronic kidney disease (CKD) exhibit alterations in tryptophan metabolism, mainly via the kynurenine pathway, due to higher enzymatic activity induced mainly by inflammation.	27832762
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Indoles produced by gut-microflora are another group of tryptophan metabolites related to inflammation and conditions accompanying CKD.	27832762
Inflammation	Altered Intercellular Communication	These organized collections of immune cells have important pathophysiologic action including cytokine production leading to inflammation as well as enzymatic conversion of cholecalciferol to calcitriol via 1-a hydroxylase.	27832822
Inflammation, Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	We found that the severity degree of the portal inflammation was in direct relation to the hepatitis activity index (HAI) and to the degree of fibrosis.	27833969
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The portal inflammation is dependent to the degree of fibrosis.	27833969
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The degree of inflammation significantly changes the distribution of cases with different degrees of fibrosis (chi-square p=0.00011 <0.001).	27833969
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Periportal inflammation, periportal necrosis and focal necrosis are the morphological aspects of the necroinflammatory process best correlated to the occurrence and development of fibrosis.	27833969
Gastrointestinal inflammation	Altered Intercellular Communication	FC directly reflects the intestinal inflammation status of a patient, and can aid in interpreting the current guidelines, which requires the integration of indirect laboratory parameters.	27834066
Inflammation, Refractory anemias, Spondylarthritis, Tooth Loss, Tooth structure	Altered Intercellular Communication	Tooth loss was common, but actual number of teeth lost, cavity occurrence, average and maximum lingual and buccal depth of space between tooth and bone, periosteal reaction, serpentine grooving surrounding teeth (considered a sign of inflammation), abscess formation, and root exposure (penetration of bone surface) were indistinguishable among controls and individuals with RA, spondyloarthropathy, and CPPD.	27834119
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Intraprostatic chronic inflammation is associated with a reduced risk of prostate cancer in patients elected to a first random biopsy set.	27834470
Inflammation, Structure of posterior cerebral artery	Altered Intercellular Communication	Advanced basic science research is warranted to investigate and develop the controversial topic of intraprostatic chronic inflammation in relation to PCa.	27834470
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Serum IL-17F and IL-23 predicted increased knee BML scores in females only, suggesting that inflammation is involved in BML pathogenesis in knee OA, especially in women.	27836676
Inflammation	Altered Intercellular Communication	These cells could contribute to inflammation by induction of T cell responses and the production of proinflammatory cytokines.	27837111
Inflammation, Synovitis, palladium, Refractory anemias, Lupus Erythematosus, Systemic	Altered Intercellular Communication	When we investigated the intensity of US findings, the joint synovitis score (GS + PD) per affected joint was lower in SLE than RA (2.0 versus 2.6, p = 0.019), while tendon inflammation score was not significantly different (2.1 versus 2.2, p = 0.738).	27837198
Refractory anemias, Inflammation, Arthropathy, Synovitis	Altered Intercellular Communication	Thus, as compared with RA, SLE arthropathy is characterized by the predominance of tenosynovitis/periextensor tendon inflammation, which is likely to develop independently from joint synovitis.	27837198
Parkinson Disease, Inflammation, Nerve Degeneration	Altered Intercellular Communication	It has been hypothesized that chronic inflammation may play an important role in the development and progression of the neurodegeneration of Idiopathic Parkinson's disease (IPD).	27837368
Inflammation	Altered Intercellular Communication	Neutrophil-lymphocyte ratio (NLR) is a marker that indicates the peripheral inflammation.	27837368
Inflammation, Nerve Degeneration	Altered Intercellular Communication	This result suggests that cerebral inflammation is in the forefront in the development of neurodegeneration in IPD, and that more evidence is needed for the role of peripheral inflammation in the development progression of disease.	27837368
Airway structure, Sleep Apnea, Obstructive	Altered Intercellular Communication	Nasal nitric oxide improved by continuous positive airway pressure therapy for upper airway inflammation in obstructive sleep apnea.	27837378
Airway structure, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	In this report, we examined the association between obstructive sleep apnea (OSA) and upper and lower airway inflammation based on nitric oxide (NO) measurements.	27837378
Airway structure	Altered Intercellular Communication	Airway inflammation was noninvasively analyzed by the measurement of nasally and orally exhaled NO; nasal value was presented as nasally exhaled NO minus orally exhaled NO.	27837378
Airway structure, Osage language	Altered Intercellular Communication	In OSA, upper but not lower airway inflammation can be increased by repetitive collapse of the upper airway.	27837378
vascular inflammations, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	Obesity may increase susceptibility to the adverse effects of PM exposure, exacerbating the effects on cardiovascular diseases and altering the biomarkers of vascular inflammation.	27838013
Proteinuria, Arteriolar hyalinosis	Altered Intercellular Communication	Multivariate Cox proportional hazard analysis showed that the glomerular lesions, proteinuria and serum creatinine were independent risk factors for renal outcomes, while interstitial fibrosis/inflammation and arteriolar hyalinosis were not independently associated with renal outcomes in the DN group.	27838100
Inflammation, Sleep-Disordered Breathing	Altered Intercellular Communication	Markers of inflammation and oxidative stress also increased as SDB became more severe.	27838124
Inflammation, Familial Mediterranean Fever, Infection	Altered Intercellular Communication	Consecutive FMF patients in attack-free period and no other cause of intermittent inflammation including infections were recruited during their regular visits in the French reference center for FMF.	27838405
Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	The architectural transcription factor high-mobility-group AT-hook 1 (HMGA1) has been involved in atherosclerosis, plaque formation, inflammation, and in the pathogenesis of insulin resistance and T2DM.	27839822
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	Inflammation accelerates tumor growth followed by reduced survival in patients with cancer.	27839896
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Our study indicates that extraosseous Gaucheromas are comprised of cellular elements with characteristics of tumor-associated macrophages, the major players in cancer related inflammation.	27839983
Inflammation, Schizophrenia	Altered Intercellular Communication	Inflammation in Schizophrenia: Cytokine Levels and Their Relationships to Demographic and Clinical Variables.	27840055
Inflammation, Schizophrenia	Altered Intercellular Communication	Inflammation may play a role in the accelerated physical aging reported in schizophrenia, though biomarker findings and associations with demographic and clinical factors are inconsistent.	27840055
Inflammation	Altered Intercellular Communication	In addition, functional group analysis demonstrated that the up-regulated genes in smaller RIAs mainly participated in the cellular response to metal ions and inorganic substances, while most of the up-regulated genes in larger UIAs were involved in inflammation and extracellular matrix (ECM) organization.	27841008
Inflammation	Altered Intercellular Communication	Moreover, compared with control arteries, inflammation was up-regulated and muscle-related biological processes were down-regulated in both smaller RIAs and larger UIAs.	27841008
Inflammation, Rupture	Altered Intercellular Communication	In addition, the healing process, involving inflammation and ECM organization, may protect IAs from rupture.	27841008
Lymphoid hyperplasia	Altered Intercellular Communication	Approximately 93.5% (29/31) of lymphoid hyperplasia appeared as the type II microvessel pattern under NBI endoscopy, whereas 96.2% (51/53) of nasopharyngeal radiation-induced inflammation exhibited the type III or IV microvessel pattern.	27841051
Intraocular inflammation	Altered Intercellular Communication	After a course of systemic therapy, intraocular inflammation subsided but visual acuity remained poor.	27842200
Inflammation, Sleep Apnea, Obstructive, Chronic Kidney Diseases	Altered Intercellular Communication	Obstructive sleep apnea syndrome (OSAS) is associated with systemic inflammation and increased risk of cardiovascular and chronic kidney disease.	27843647
Arthralgia, Inflammation, Fever, CTCAE, Infection	Altered Intercellular Communication	The affected pathways in our study correlate well with the clinical manifestation like fever, inflammation, energy deprivation and joint pain during the infections.	27845374
nervous system disorder, Inflammation	Altered Intercellular Communication	Furthermore, several neurological diseases which cause central nervous system inflammation or degeneration were related to BP, and the association was strongest between MS and BP.	27845416
Inflammation	Altered Intercellular Communication	Interestingly, the Sod1-/- mice showed higher levels of circulating cytokines than WT mice, suggesting that the accelerated aging phenotype shown by the Sod1-/- mice could result from increased inflammation arising from an accelerated accumulation of senescent cells.	27846439
Inflammation	Altered Intercellular Communication	The accumulation of senescent cells in turn leads to increased inflammation, which plays a major role in the loss of function and increased pathology that are hallmark features of aging.	27846439
Inflammation, Fibrosis Assessment, Necrosis	Altered Intercellular Communication	Findings which predicted fibrosis progression, were baseline total inflammation (odds ratio 1.7, 95% CI 1.01-2.8), cumulative total inflammation (1.8, 95% CI 1.01-3.2, rosette formation (2.8, 95% CI 1.1-7.1), absence of pericholangitis (0.4, 95% CI 0.1-1.0) and necrosis (1.4, 95% CI 1.0-2.0).	27846740
Inflammation, Cholestasis, Liver Cirrhosis, Necrosis	Altered Intercellular Communication	Risk factors for the development of cirrhosis were cholestasis (4.6, 95% CI 1.2-16.9), interphase inflammation (3.4, 95% CI 1.1-10.4), and necrosis (3.3, 95% CI 1.2-9.7).	27846740
Inflammation, Necrosis	Altered Intercellular Communication	In a cumulative model, cumulative total inflammation (4.5, 95% CI 1.4-15.0), necrosis (6.7, 95% CI 1.3-34.6), or cumulative immunoglobulin G load (61.8, 95% CI 2.0-1954.3) were risk factors.	27846740
Inflammation, Necrosis, Fibrosis Assessment, Cholestasis, Liver Cirrhosis	Altered Intercellular Communication	The total cumulative inflammatory activity predicts the progression of fibrosis, whereas baseline fibrosis, interphase inflammation, cholestasis, necrosis, as well as the cumulative total inflammation and cumulative immunoglobulin G, are risk factors for cirrhosis.	27846740
Alopecia Areata, Inflammation	Altered Intercellular Communication	Alopecia areata is characterized by perifollicular/intrafollicular lymphocyte infiltration of the lower bulb and inflammation in the upper dermis.	27846747
Acute inflammation, Hypoalbuminemia	Altered Intercellular Communication	A 50 % elevated de-novo albumin synthesis rate was seen in patients with acute inflammation and marked hypoalbuminemia, while patients with marginal hypoalbuminemia before the start of surgery had a normal albumin synthesis rate.	27846908
Inflammation, Hypoalbuminemia	Altered Intercellular Communication	In acute inflammation with marked hypoalbuminemia, the transcapillary escape rate was no different from normal.	27846908
Hyperparathyroidism, Primary	Altered Intercellular Communication	Primary hyperparathyroidism is characterized by increased levels of serum calcium and parathyroid hormone.	27847113
Dental Plaque	Altered Intercellular Communication	Cap inflammation leads to higher plaque cap strain and lower cap stress: An MRI-PET/CT-based FSI modeling approach.	27847118
Inflammation, Dental Plaque	Altered Intercellular Communication	The impact of cap inflammation on plaque stress/strain and flow shear stress were investigated.	27847118
Inflammation, Dental Plaque	Altered Intercellular Communication	18FDG-PET/CT and MRI data were acquired from 4 male patients (average age: 66) to assess plaque characteristics and inflammation.	27847118
Fibrous, Inflammation	Altered Intercellular Communication	Material stiffness for the fibrous cap was adjusted lower to reflect cap weakening causing by inflammation.	27847118
Hypertension, CTCAE	Altered Intercellular Communication	Cap inflammation may lead to large cap strain conditions when combined with thin cap and hypertension.	27847118
Inflammation, Dental Plaque	Altered Intercellular Communication	This shows the influence of inflammation on stress/strain calculations which are closely related to plaque assessment.	27847118
Inflammation	Altered Intercellular Communication	BACKGROUND Serum albumin (ALB) may be low during acute inflammation, but it is also affected by nutritional status.	27848931
Inflammation	Altered Intercellular Communication	These results suggest that, in addition to inflammation, assessment of patient nutritional status could also aid in identifying CD activity.	27848931
Inflammation, Myeloid	Altered Intercellular Communication	Interplay of Toll-Like Receptor 9, Myeloid Cells, and Deubiquitinase A20 in Periodontal Inflammation.	27849177
Inflammation, Periodontitis	Altered Intercellular Communication	Clinically, A20 was modestly upregulated in human gingival tissue specimens from chronic periodontitis patients, further confirming the biological relevance of A20 in periodontal inflammation.	27849177
Inflammation, Periodontal Diseases	Altered Intercellular Communication	We conclude that TLR9 modulates periodontal disease progression at both the cellular and molecular level and identify A20 as a novel downstream signaling molecule in the course of periodontal inflammation.	27849177
Inflammation, Periodontitis, Chronic inflammatory disorder	Altered Intercellular Communication	Understanding the regulation of the TLR9 signaling pathway and the involvement of A20 as a limiting factor of inflammation will uncover alternative therapeutic targets to treat periodontitis and other chronic inflammatory diseases.	27849177
Inflammation, Diabetic Retinopathy	Altered Intercellular Communication	Myeloid-Related Protein-14/MRP-14/S100A9/Calgranulin B is Associated with Inflammation in Proliferative Diabetic Retinopathy.	27849448
Inflammation, PDR gene	Altered Intercellular Communication	Increased MRP-14 levels are associated with inflammation in PDR.	27849448
Nasopharyngeal carcinoma	Altered Intercellular Communication	A Novel Inflammation-Based Stage (I Stage) Predicts Overall Survival of Patients with Nasopharyngeal Carcinoma.	27854304
Inflammation, hepcidin	Altered Intercellular Communication	Hepcidin-25 serves as a key peptide in the regulation of iron homeostasis and inflammation.	27855289
Inflammation, Anemia, Sickle Cell, Hemolysis (biological function), Albuminuria	Altered Intercellular Communication	Albuminuria, serum antioxidant enzyme levels and markers of hemolysis and inflammation in steady state children with sickle cell anemia.	27855647
Inflammation, Albuminuria, Hemolysis (biological function)	Altered Intercellular Communication	Albuminuria is associated with decreased antioxidant capacity and increased levels of markers of hemolysis and inflammation.	27855647
Cardiac Arrest, Inflammation, Hemolysis (biological function), Kidney Diseases	Altered Intercellular Communication	Therefore, strategies targeting the reduction of sickling and subsequent hemolysis, oxidative stress and inflammation could help preventing or at least delaying the progression of kidney disease in SCA children.	27855647
Refractory anemias, Sarcoidosis, Pulmonary, Dysbiosis	Altered Intercellular Communication	Distal airway dysbiosis is present in untreated early RA and similar to that detected in sarcoidosis lung inflammation.	27855721
Inflammation, Dehydration	Altered Intercellular Communication	Studies are necessary to understand whether correcting underlying dehydration and inflammation further improves patients' outcomes.	27856199
Cutaneous Radiation Injury, TRAF3IP2 gene, Inflammation, Granulation finding	Altered Intercellular Communication	aCT1 is a Cx43 mimetic peptide that in preclinical studies accelerated wound closure, decreased inflammation and granulation tissue area, and normalized mechanical properties after cutaneous injury.	27856288
Inflammation, Obesity	Altered Intercellular Communication	The prevalence of obesity or equivalent was 65%, of which 30% did not have inflammation.	27856456
Inflammation, Chronic heart failure	Altered Intercellular Communication	Myocardial 123I-mIBG scintigraphy in relation to markers of inflammation and long-term clinical outcome in patients with stable chronic heart failure.	27858345
Chronic heart failure, Myocarditis, Congestive heart failure	Altered Intercellular Communication	Chronic heart failure (CHF) results in both increased cardiac sympathetic activity and myocardial inflammation.	27858345
Inflammation, Congestive heart failure	Altered Intercellular Communication	Inflammation and cardiac sympathetic activity seem not to be related in stable CHF patients.	27858345
Papillary, Inflammation, palladium	Altered Intercellular Communication	Dental examination included: 1) dental findings (decayed, missing, and/or filled adult teeth [DMF-T] index); 2) gingival inflammation (papillary bleeding index [PBI]); and 3) periodontal status (probing depth [PD], attachment loss [AL]).	27858553
Tumor necrosis, Immune-mediated	Altered Intercellular Communication	Repeat imaging demonstrated increased size of the lesion, reflecting immune-mediated inflammation and tumor necrosis.	27858578
Inflammation	Altered Intercellular Communication	The patient underwent partial hepatectomy for the cystic mass of the liver and a final diagnosis of chronic inflammation of an intrahepatically located accessory GB was made.	27858902
Airway structure, Allergy - Charge Type Reason	Altered Intercellular Communication	Double-blind placebo-controlled challenge showed that peanut oral immunotherapy was effective for severe allergy without negative effects on airway inflammation.	27859599
Airway structure, Hypersensitivity	Altered Intercellular Communication	Peanut OIT was efficacious in severe allergies without negative effects on airway inflammation, but unpredictable long-term reactions might occur.	27859599
Inflammation	Altered Intercellular Communication	We tested the hypothesis that birthweight was inversely associated with serum high sensitivity C reactive protein assay (hsCRP), a measure of both innate immunity and systemic inflammation.	27859847
Inflammation, Cardiovascular Diseases, Osage language, Hypoxia, Endothelial dysfunction	Altered Intercellular Communication	Intermittent hypoxia, endothelial dysfunction and adipose tissue-mediated inflammation have all been linked to cardiovascular disease in OSA.	27860068
Inflammation, Traumatic injury	Altered Intercellular Communication	For various reasons, including trauma and inflammation, it may become elongated.	27860211
Inflammation, Neoplasms	Altered Intercellular Communication	Chronic inflammation plays an important role in tumor progression.	27860387
Chronic lymphocytic inflammation, Pontine structure, Clippers, Epstein-Barr Virus Infections	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) with intracranial Epstein-Barr virus infection: A Case Report.	27861371
Chronic lymphocytic inflammation, Pontine structure, Clippers, Inflammatory disorder	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disorder in the central nervous system (CNS) with distinct clinical, radiological, and pathological features.	27861371
Inflammation	Altered Intercellular Communication	In the same group, increased non-classical monocyte subset up-regulated TLR4-NFkB-iNOS and p38MAPK pathway, stimulated TNFa/nitrite production and elicited systemic inflammation.	27861595
Periodontal Diseases, Inflammation, RTEL1 gene	Altered Intercellular Communication	Whether periodontal disease is a direct or indirect cause of NHL, or is a marker of underlying systemic inflammation and/or immune dysregulation, warrants further investigation.	27861844
Primary malignant neoplasm, Periodontal Diseases, Chronic disease	Altered Intercellular Communication	Periodontal disease is a chronic inflammatory condition that has been associated with chronic diseases, including cancer.	27861844
Inflammation, Chronic disease, MS gene	Altered Intercellular Communication	After CIS, a chronic disease course with ongoing inflammation and relapses might occur, resulting in a diagnosis of multiple sclerosis (MS).	27862730
Inflammation, Tubulitis Assessment	Altered Intercellular Communication	At 1 year, subclinical inflammation occurred more frequently in group A than group B (inflammation score [i] >0: 21.4% vs. 8.8%, p = 0.047; tubulitis score [t] >0: 19.6% vs. 8.7%, p = 0.076; i + t: 1.14 +- 1.21 vs. 0.72 +- 1.01, p = 0.038).	27862923
Unknown (origin) (qualifier value), Pericarditis, CTCAE, Inflammation	Altered Intercellular Communication	Pericarditis is an inflammation of the pericardium and 90% of isolated cases of acute pericarditis are idiopathic or viral.	27863892
Psoriatic Juvenile Idiopathic Arthritis, Inflammation, Psoriasis, Liver diseases	Altered Intercellular Communication	FABP4 may be a marker of psoriasis, and FABP3 may be associated with inflammation or liver disorders in psoriatic patients.	27864793
Inflammation, Pseudoaneurysm, Bacterial Endocarditis	Altered Intercellular Communication	At autopsy, destruction of the noncoronary cusp of the aortic valve by bacterial endocarditis was found with extension of the inflammation into a pseudoaneurysm of the SoV with surrounding abscess formation involving the atrioventricular node.	27864952
Sepsis, Inflammation, Hypoxia	Altered Intercellular Communication	Adrenomedullin is released by different tissues in hypoxia, oxidative stress, and inflammation and is found in general and medical patients and, recently, in sepsis patients in emergency departments.	27865148
Refractory anemias, Inflammation, Erosion lesion	Altered Intercellular Communication	These cytokines, as upstream inhibitors of IL-34, may thus contribute to antagonize inflammation and bone erosions in RA.	27865758
Inflammation, Osseous metaplasia, Fibrosis Assessment, Metaplasia, Calcified (qualifier), Cartilaginous metaplasia	Altered Intercellular Communication	AVS cusps showed structural remodeling as severe fibrosis (100%), calcific nodules (100%), neoangiogenesis (81%), inflammation (71%), bone metaplasia with or without hematopoiesis (6% and 53%, respectively), adipose metaplasia (16%), and cartilaginous metaplasia (7%).	27866029
Inflammation, Atherosclerosis	Altered Intercellular Communication	Improvements in inflammation and insulin resistance seem to be mechanisms involved in the mitigation of atherosclerosis by empagliflozin.	27866224
Inflammation	Altered Intercellular Communication	Accumulation of tissue macrophages is a significant characteristic of disease-associated chronic inflammation, and facilitates the progression of disease pathology.	27866511
Dysplasia, Lichenoid inflammation	Altered Intercellular Communication	Disease-free status was less likely for erythroleukoplakia (P=0.022), 'high-grade' dysplasia (P<0.0001), and with lichenoid inflammation (P=0.028).	27866683
Inflammation, Tubulointerstitial nephritis and uveitis	Altered Intercellular Communication	In TINU syndrome, inflammation affects the renal tubules, interstitial tissue, and uveal tract.	27867184
Inflammation, Fibrosis Assessment, Hepatomegaly, FAM126A gene	Altered Intercellular Communication	After 30 months of follow-up, the liver pathology of the mice fell into four groups: G1, chronic inflammation solely; G2, chronic inflammation and fibrosis; G3, inflammation, fibrosis, and hepatomegaly accompanied by rectal prolapse (4-12%); and G4, hepatomegaly and spontaneous HCC (12-15%).	27868197
Inflammation, Leukopenia	Altered Intercellular Communication	The lack of massive tissue inflammation, probably due to the neutropenia in our patient, has not been described by other authors.	27869489
Inflammation, Anemia	Altered Intercellular Communication	Further studies in patients with more severe anaemia and patients with inflammation are warranted.	27870058
Inflammation, Malnutrition, Overhydration, HD Term Type, Cardiac dysfunction, Muscle Tissue	Altered Intercellular Communication	NT-proBNP may be an independent biomarker for malnutrition in HD patients, especially in patients with muscles loss, regardless of chronic inflammation, cardiac dysfunction, or overhydration.	27870908
Inflammation, Edema	Altered Intercellular Communication	The muscles showed edema and scattered inflammation at the very beginning, and then gradually formed mature bone tissue.	27871317
Inflammation	Altered Intercellular Communication	Our results suggest that age and virus mediated inflammation are correlated with disease phenotypes while additional factors such as host or HTLV-1 genetics and gender may influence disease susceptibility.	27871430
Gingivitis	Altered Intercellular Communication	During a review of her medical history, the patient reported using cannabis frequently during a 3-year period, which coincided with the occurrence of gingival inflammation.	27871617
Inflammation, Data types - Address	Altered Intercellular Communication	A large body of evidence suggests that inflammation is closely associated with AD pathogenesis and may be a promising target pathway for such interventions.	27872486
Inflammation, Data types - Address	Altered Intercellular Communication	However, little is known about the association between systemic inflammation and preclinical AD pathophysiology.	27872486
Nausea, Diarrhea, Inflammatory disease of mucous membrane, Fatigue	Altered Intercellular Communication	Frequent (any grade) treatment-related adverse events (AEs) included diarrhea (83%), rash/acne (83%), fatigue (79%), mucosal inflammation (59%), and nausea (59%).	27872953
Inflammation, Rectal Carcinoma	Altered Intercellular Communication	The current study examined the association between systemic inflammation and nCRT in patients with rectal cancer.	27873100
Aneurysm, Inflammation	Altered Intercellular Communication	In the light of recent reports of the association of wall enhancement with unstable aneurysms, we considered wall enhancement to be a marker of inflammation and remodeling of the aneurysm wall, resulting in chronic hemorrhagic suffusion in the subarachnoid spaces.	27873743
Communicable Diseases, Traumatic injury	Altered Intercellular Communication	Oral PG is often caused by constant low-grade infection, minor trauma, poor oral hygiene, and due to hormonal disturbances.	27874157
Acromegaly, Neoplasms	Altered Intercellular Communication	We present data from the PRIMARYS study on the impact of the SSA lanreotide, associated with tumour volume and hormonal improvements, on glucose and other metabolic parameters in acromegaly.	27874199
Short Bowel Syndrome, antimony, Chronic intestinal failure	Altered Intercellular Communication	An impaired hormonal "ileo-colonic brake" may contribute to rapid gastric emptying, gastric hypersecretion, high ostomy losses, and the need for parenteral support in end-jejunostomy short bowel syndrome (SBS) patients with intestinal failure (IF).	27875281
Inflammation, Chronic heart failure	Altered Intercellular Communication	Orosomucoid as prognosis factor associated with inflammation in acute or nutritional status in chronic heart failure.	27875723
Inflammation, Heart failure	Altered Intercellular Communication	Inflammation and nutritional state are involved in the pathogenesis of heart failure (HF).	27875723
Inflammation, Injury of musculoskeletal system, abdominal adhesions, Tissue Adhesions	Altered Intercellular Communication	The etiology for this phenomenon was thought to be abdominal adhesions caused by inflammation and viscero-somatic reflexes caused by adhesions or injury to visceral or musculoskeletal system structures.	27876238
Inflammation, trauma to the abdomen, Digestive Epilepsy, Tissue Adhesions, Epilepsy	Altered Intercellular Communication	If substantiated in further research, present study results will require further examination of the mechanisms of action for epilepsy, and suggest the need for re-examination of older formulations of abdominal epilepsy, including the place of abdominal injury, inflammation, and adhesions in epileptic pathology.	27876238
Kidney Failure, Chronic, Atherosclerosis	Altered Intercellular Communication	Activation of the CXCL16/CXCR6 Pathway by Inflammation Contributes to Atherosclerosis in Patients with End-stage Renal Disease.	27877078
Inflammation, Atherosclerosis	Altered Intercellular Communication	Background: Chronic inflammation plays a critical role in the progression of atherosclerosis (AS).	27877078
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Conclusions: Inflammation contributed to foam cell formation in the radial arteries of ESRD patients via activation of the CXCL16/CXCR6 pathway, which may be regulated by P2X7R.	27877078
Inflammation	Altered Intercellular Communication	These results are consistent with the hypothesis that diet-associated inflammation determines LTL.	27878970
Respiratory Distress Syndrome, Adult, Inflammation	Altered Intercellular Communication	Expression of miRNA is increased in blood leukocytes of patients with ARDS at day 0 and day 3 and rises further by day 7, when systemic inflammation is subsiding.	27879560
Cellulitis	Altered Intercellular Communication	Recurrent Orbital Inflammation Mimicking Orbital Cellulitis Associated With Orbitopalpebral Venous Lymphatic Malformation.	27879620
Orbital Pseudotumor	Altered Intercellular Communication	Over 8 months of follow up, he had 2 acute episodes of severe orbital inflammation that warranted hospitalization and treatment with intravenous antibiotic, steroids and surgical debulking.	27879620
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterised by progressive and irreversible airflow limitation associated with chronic inflammation involving cytokines and metalloproteinases (MMPs).	27880043
Airway structure, Inflammation, Chest tightness	Altered Intercellular Communication	We propose that the chest tightness relieved with bronchodilator use was attributed to airway constriction resulting from inflammation with lymphocytes and macrophages and/or that the chest tightness was directly attributed to airway inflammation.	27880056
Inflammation	Altered Intercellular Communication	The underlying pathogenesis was postulated to be localised inflammation and pathological aberrant vessels formation.	27881024
Inflammation, SDSL gene	Altered Intercellular Communication	It was found to inhibit inflammation and promote vascular maturation at the neomembrane of CSDH.	27881024
Arterial Stiffness, Inflammation	Altered Intercellular Communication	Patients with peritoneal dialysis are in the persistent inflammation state and have elevated arterial stiffness.	27881094
Non-alcoholic Fatty Liver Disease, Somatotropin deficiency	Altered Intercellular Communication	Growth hormone deficiency (GHD) is associated with non-alcoholic fatty liver disease (NAFLD).	27881164
Prediabetes syndrome, diabetic	Altered Intercellular Communication	Assessment of Carotid Plaque Inflammation in Diabetic and Nondiabetic Patients-An Exploratory Ultrasmall Superparamagnetic Iron Oxide-Enhanced Magnetic Resonance Imaging Study.	27881291
Inflammation, Atheroma, atherosclerotic	Altered Intercellular Communication	Ultrasmall superparamagnetic iron oxide (USPIO)-enhanced magnetic resonance (MR) imaging enables the identification of inflammation within the atheroma, predominantly by USPIO uptake by macrophages present in atherosclerotic tissue.	27881291
Inflammation, diabetic	Altered Intercellular Communication	Diabetic patients, however, may have dysfunctional macrophage activity, which may affect utilization of USPIO in identifying plaque inflammation in this patient cohort.	27881291
Inflammation, Malnutrition	Altered Intercellular Communication	Assessment of Regression Models for Adjustment of Iron Status Biomarkers for Inflammation in Children with Moderate Acute Malnutrition in Burkina Faso.	27881597
Inflammation	Altered Intercellular Communication	Regression analysis is an alternative to adjust SF and may be preferable in research settings, because it can take morbidity and severity of inflammation into account.	27881597
Inflammation	Altered Intercellular Communication	The levels of systemic inflammation markers increased with the involvement of larger and/or more joints.	27882446
Inflammation	Altered Intercellular Communication	Combined treatment might be particularly relevant in those conditions where increased inflammasome activation may lead to GR degradation and steroid-unresponsive inflammation.	27883019
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation has a key role in the process of atherosclerosis.	27883201
Inflammation, Foot Ulcer, diabetic	Altered Intercellular Communication	Negative pressure wound therapy inhibits inflammation and upregulates activating transcription factor-3 and downregulates nuclear factor-kB in diabetic patients with foot ulcerations.	27883358
Inflammation, diabetic	Altered Intercellular Communication	After 7 days of treatment, NPWT could obviously promote diabetic wound healing because of the mild inflammation and the dense cell-deposited matrix.	27883358
Uremia, Inflammation, Bacterial Infections, Vascular calcification	Altered Intercellular Communication	The ensuing impairment of neutrophil function can contribute to the chronic inflammation state of uremic patients, and the increased risk of bacterial infections or vascular calcifications.	27884120
Infectious gastroenteritis, Gastroenteritis	Altered Intercellular Communication	increased adult burden of infectious gastroenteritis and genetic diversity of circulating rotaviruses; adults infected with rotavirus developed more severe gastroenteritis symptoms (p<0.01) accompanied with mild intestinal and blood inflammations.	27884652
Inflammation, Crohn Disease	Altered Intercellular Communication	Rectal inflammation was present in 29 patients with Crohn's disease (29.2%) and in 2 without Crohn's (6.7%).	27885389
Inflammation, Crohn Disease	Altered Intercellular Communication	Our study demonstrates that while both groups can have similar MR imaging features, accompanying rectal inflammation was more commonly seen in Crohn's disease.	27885389
Inflammation, Neoplasms, Fibrosis Assessment, FAM126A gene, ABR gene	Altered Intercellular Communication	The presence of MDB in tumours was associated with the steatohepatitic variant of HCC, which also showed fatty change, ballooning of tumour cells, MDBs, inflammation and pericellular fibrosis (P<.001).	27885796
Inflammation	Altered Intercellular Communication	Inflammation plays an important role in development of coronary collateral circulation (CCC).	27885839
Inflammation, Stomach Carcinoma, Atrophic	Altered Intercellular Communication	Patients with cagA- and vacA-positive H. pylori have a higher risk of severe inflammation and atrophy and should therefore be monitored for the development of gastric cancer.	27886029
Inflammation, Impaired cognition, Atherosclerosis	Altered Intercellular Communication	Our findings suggest that systemic chronic inflammation, potentially associated with underlying atherosclerosis, is related to cognitive impairment and decline two decades later, in elderly individuals with pre-existing CVD.	27886564
Airway structure, Asthma	Altered Intercellular Communication	Fractional exhaled nitric oxide (FeNO) is considered an alternative marker of eosinophilic airway inflammation and is sometimes incorporated in the diagnosis of asthma.	27886852
Cancer-related fatigue	Altered Intercellular Communication	Corticotropin-releasing factor (CRF) is a neurohormone released from the paraventricular nucleus of the hypothalamus into the median eminence to elicit release of adrenocorticotrophin from the anterior pituitary.	27887910
Communicable Diseases, Inflammation	Altered Intercellular Communication	There was evidence of CBG cleavage in early infection both in patients with and without systemic inflammation and regardless of culture status.	27887960
Inflammation, Leukocytosis, Hepatitis, Cachexia	Altered Intercellular Communication	Skin carcinogenesis was associated with progressive, severe, systemic inflammation (leukocytosis, hepatitis, splenitis), significant mortality and cachexia.	27888116
Hepatic inflammation, muscle mass	Altered Intercellular Communication	Preservation of muscle mass and reduced hepatic inflammation were associated with down-regulation of the NF-kB canonical pathway and with reduced oxidative stress, respectively.	27888116
Inflammation, Fibromyalgia, Federated States of Micronesia	Altered Intercellular Communication	Chronic inflammation, which changes the neurotransmitter metabolism and kindles neuroendocrine system dysfunction in the central nervous system, might cause fibromyalgia (FM) formation.	27888118
Inflammation, cyclophosphamide/methotrexate/vincristine protocol, Chronic osteomyelitis	Altered Intercellular Communication	Thus, we investigated whether chronic osteomyelitis (COM), a disease characterized by chronic inflammation, increases FM risk.	27888118
Inflammation, Fibromyalgia, Federated States of Micronesia	Altered Intercellular Communication	Chronic inflammation, which changes the neurotransmitter metabolism and kindles neuroendocrine system dysfunction in the central nervous system, might cause fibromyalgia (FM) formation.	27888118
Parkinson Disease, Inflammation, palladium, Neurodegenerative Disorders	Altered Intercellular Communication	Inflammation is likely a key contributor to the pathogenesis of Parkinson's disease (PD), a progressively debilitating neurodegenerative disease that is accompanied by a pathological accumulation of the a-synuclein protein in a staged manner through the brain.	27888296
palladium, Inflammation	Altered Intercellular Communication	Toll-like receptor (TLR) signaling is a major pathway mediating inflammation and, in particular, TLR2 is increasingly being implicated in PD.	27888296
Inflammation, Chronic sinusitis, Craniosynostosis, Chronic infectious disease	Altered Intercellular Communication	Eosinophilic chronic rhinosinusitis (eCRS) has recently been recognized as a CRS subtype characterized by inflammation rather than chronic infection.	27888519
Inflammation, Axial spondyloarthritis	Altered Intercellular Communication	Prevalence and topographic distribution of spinal inflammation on MR imaging in patients recently diagnosed with axial spondyloarthritis.	27889235
HSPG2 wt Allele	Altered Intercellular Communication	Recombinant serotype 2 adeno-associated viral (rAAV2) vectors expressing either OB-R shRNA (rAAV2-shOB-R) or none (rAAV2-null) were injected into 4 or 16 week-old BALB/c NOD/LtJ (NOD) mice and resulted in a modest reduction in glandular inflammation in the SjS model.	27889607
Communicable Diseases, Inflammation, Impaired cognition, Breast Carcinoma	Altered Intercellular Communication	Although the pathophysiology of the condition is complex, alterations in systemic cytokines, signaling molecules activated in response to infection or injury that trigger inflammation, are a possible mechanism linked to cognitive dysfunction in breast cancer and other conditions.	27890459
Inflammation, Neoplasms, Glioblastoma Multiforme Pathway	Altered Intercellular Communication	Functional analysis performed on each group reveals sub-networks related to neoplasia for group 1, glioma with inflammation for group 2 and neurogenesis for group 3.	27890679
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Purpose The sequelae of cancer treatment may increase systemic inflammation and create a phenotype at increased risk of functional decline and comorbidities, leading to premature mortality.	27893337
Pain Distress Question, Primary malignant neoplasm, Inflammation, GDC Comorbidity Terminology	Altered Intercellular Communication	Survivors treated with surgery, radiation, and chemotherapy accumulated a significantly greater burden of comorbid conditions and suffered greater pain associated with inflammation over time after cancer treatment than did the control group.	27893337
Sepsis, Inflammation	Altered Intercellular Communication	The downregulation of blood monocyte HLA-DR expression also occurs in tissue infiltrative cells in a context of acute clinical inflammation, especially sepsis.	27893741
Inflammation, Telangiectasis, Pulmonary Fibrosis	Altered Intercellular Communication	Dysbiosis was more severe in patients with skin telangiectasias (p = 0.020), pitting scars (p = 0.023), pulmonary fibrosis (p = 0.009), and elevated serum markers of inflammation (p < 0.001).	27894337
Inflammation, Lupus Erythematosus	Altered Intercellular Communication	Association between the cytotoxic T-lymphocyte antigen-4 mutations and the susceptibility to systemic lupus erythematosus; Contribution markers of inflammation and oxidative stress.	27894401
Inflammation, Intraepithelial Neoplasia	Altered Intercellular Communication	Fifty-four lesions (65%) were histologically diagnosed as SESCCs and the others as low-grade intraepithelial neoplasia or inflammation.	27895406
Communicable Diseases, Acute inflammation	Altered Intercellular Communication	It characteristically presents with acute inflammation, resulting in demyelination, often following an infectious disease.	27896893
Inflammation, Sleep Apnea, Obstructive, Carotid Intima-Media Thickness, Metabolic Syndrome X	Altered Intercellular Communication	Impact of inflammation and oxidative stress on carotid intima-media thickness in obstructive sleep apnea patients without metabolic syndrome.	27896929
Inflammation, Osage language	Altered Intercellular Communication	This study tested the hypothesis that inflammation and oxidative stress determined carotid IMT in patients with OSA.	27896929
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Toll-like receptor 4 signalling mediates inflammation in skeletal muscle of patients with chronic kidney disease.	27897392
Uremia, Inflammation, Skeletal muscle structure, Cachexia	Altered Intercellular Communication	Inflammation in skeletal muscle is implicated in the pathogenesis of insulin resistance and cachexia but why uremia up-regulates pro-inflammatory cytokines is unknown.	27897392
Chronic Kidney Diseases, Myositis	Altered Intercellular Communication	CKD promotes muscle inflammation through an up-regulation of TLR4, which may activate downward inflammatory signals such as TNF-a and NFkB-regulated genes.	27897392
Chronic Kidney Diseases, Myositis	Altered Intercellular Communication	CKD promotes muscle inflammation through an up-regulation of TLR4, which may activate downward inflammatory signals such as TNF-a and NFkB-regulated genes.	27897392
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Cancer anorexia: hypothalamic activity and its association with inflammation and appetite-regulating peptides in lung cancer.	27897393
Primary malignant neoplasm, Anorexia	Altered Intercellular Communication	Energy homeostasis is mediated by the hypothalamus, whose inflammation-induced functional derangements contribute to the onset of anorexia in cancer.	27897393
Inflammation	Altered Intercellular Communication	Low SMD appears to correlate with fat accumulation in muscle and is associated with inflammation.	27897411
Inflammation	Altered Intercellular Communication	Chronic inflammation, changes in body composition, and declining physical function are hallmarks of the ageing process.	27897412
Inflammation	Altered Intercellular Communication	Interleukin-4 (IL-4) together with interleukin-13 (IL-13) play an important role in inflammation and wound repair, and are known to be upregulated in human skeletal muscle after strenuous physical exercise.	27897439
Inflammation	Altered Intercellular Communication	Quercetin (Qe) plays an important role in inflammation, antibacterial, anticancer, and aging.	27898345
Inflammation, Pain Distress Question	Altered Intercellular Communication	Our findings showed a relationship between inflammation and LBP by establishing that low IL-6 plasma levels preceded outcome (LBP recovery), supporting the concept that proinflammatory cytokines promote pain.	27898478
Inflammation, Idiopathic osteoarthritis	Altered Intercellular Communication	Chronic synovial inflammation causes primary osteoarthritis, but it is unknown whether chronic systemic inflammation does, too.	27898694
Inflammation, Idiopathic osteoarthritis, Liver Cirrhosis	Altered Intercellular Communication	Patients with cirrhosis have chronic systemic inflammation and therefore we examined the association between cirrhosis and primary osteoarthritis of the hip and knee.	27898694
Inflammation, Idiopathic osteoarthritis, Liver Cirrhosis	Altered Intercellular Communication	Cirrhosis, and thus chronic systemic inflammation, is not a risk factor for primary osteoarthritis.	27898694
Airway structure, Communicable Diseases, ARCN1 gene	Altered Intercellular Communication	Relationships between Mucosal Antibodies, Non-Typeable Haemophilus influenzae (NTHi) Infection and Airway Inflammation in COPD.	27898728
ARCN1 gene, Airway structure	Altered Intercellular Communication	Non-typeable Haemophilus influenzae (NTHi) is a key pathogen in COPD, being associated with airway inflammation and risk of exacerbation.	27898728
ARCN1 gene, Communicable Diseases, Inflammation	Altered Intercellular Communication	The aim of our study (NCT01701869) was to quantify the amount and specificity of antibodies against NTHi in the lungs and the associated risk of infection and inflammation in health and COPD.	27898728
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	NTHi was detected in the lungs of 7 of the COPD patients (NTHi+ve-29%) and these patients had a higher median number of previous exacerbations than NTHi-ve patients as well as evidence of increased systemic inflammation.	27898728
Airway structure, ARCN1 gene	Altered Intercellular Communication	This decrease in total and NTHI-specific IgG1 was associated with greater systemic and airway inflammation and a history of more frequent exacerbations and may explain the susceptibility of some COPD patients to the impacts of NTHi.	27898728
Inflammation, Knee pain	Altered Intercellular Communication	Dietary fiber may reduce knee pain, in part by lowering body weight and reducing inflammation.	27899003
Inflammation	Altered Intercellular Communication	Gene ontology analysis showed higher prevalence of VFA-associated genes than that of SFA-associated genes, among the genes associated with inflammation, oxidative stress, immune response, lipid metabolism, and glucose metabolism.	27899146
Inflammation, Edema	Altered Intercellular Communication	He was treated with topical ganciclovir and ketorolac, and the inflammation and oedema resolved.	27899387
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Secondary outcome parameters included biomarkers for inflammation, coagulation and endothelial function and lipid profiles.	27899529
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Cancer causes systemic inflammation which interrupts iron metabolism leading to a functional iron deficiency (FID).	27900547
Inflammation, Hypochromatism	Altered Intercellular Communication	We assessed the numbers of patients with abnormal values for haemoglobin, % hypochromic red cells (>5% indicates iron-restricted erythropoiesis) and CRP (>10 indicates systemic inflammation).	27900547
Ischemia, Inflammation	Altered Intercellular Communication	Diabetic hyperglycemia damages peripheral nerves by triggering ischemia, oxidative stress, and inflammation.	27901334
Inflammation	Altered Intercellular Communication	Cardiac Troponin Release is Associated with Biomarkers of Inflammation and Ventricular Dilatation During Critical Illness.	27902530
Troponin T, Cardiac Muscle, Inflammation, Ventricular dilatation (disorder)	Altered Intercellular Communication	We hypothesized that there was an association between cardiac troponin T (cTnT) and biomarkers of systemic inflammation and ventricular dilatation.	27902530
Inflammation, Superinfection	Altered Intercellular Communication	Skin overlying the typical subcutaneous inflammation may appear normal, and bacterial superinfections of the skin sometimes mask the underlying LP.	27902603
Hyperglycemia	Altered Intercellular Communication	A state of obesity-related inflammation plus hyperglycemia may trigger increased alloreactivity and should call for adequate immunosuppression.	27903445
APP gene, Inflammation, Aortic Aneurysm, Abdominal, Rupture	Altered Intercellular Communication	Abdominal aortic aneurysm (AAA) wall inflammation and mechanical structural stress may influence AAA expansion and lead to rupture.	27903534
Inflammation, Blood Clot	Altered Intercellular Communication	Compared with other factors, structural stress was the best predictor of inflammation (receiver-operating characteristic curve area under the curve =0.59), with higher accuracy seen in regions with high thrombus burden (area under the curve =0.80).	27903534
Inflammation, Blood Clot	Altered Intercellular Communication	Increased aortic wall inflammation, demonstrated by 18F-FDG positron emission tomography, was observed in AAA regions with thick intraluminal thrombus subjected to high mechanical stress, suggesting a potential mechanistic link underlying aneurysm inflammation.	27903534
Inflammation, Electrocardiogram: myocardial infarction (finding), Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	The association of plasma oxidative status and inflammation with the development of atrial fibrillation in patients presenting with ST elevation myocardial infarction.	27905214
Inflammation	Altered Intercellular Communication	Oxidative stress and inflammation may cause structural and electrical remodeling in the atria making these critical processes in the pathology of AF.	27905214
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	The main finding of this study is that oxidative stress and inflammation parameters were associated with the development of AF in patients presenting with STEMI.	27905214
Cartilage destruction, Inflammation	Altered Intercellular Communication	IFP may trigger both cartilage destruction and inflammation of the synovium, but not through leptin or adiponectin.	27908299
Vascular Diseases, Inflammation, Impaired cognition, Myocardial dysfunction, Data types - Address	Altered Intercellular Communication	Whereas cognitive impairment has been linked to HF through perfusion defects, angiopathy, and inflammation, whether patients with AD present with myocardial dysfunction, and if the 2 conditions bear a common pathogenesis as neglected siblings are unknown.	27908343
FGFR1OP gene	Altered Intercellular Communication	We hypothesized that FOP patients develop characteristic deficiencies in inflammation-related trace elements and display a chronically increased inflammatory cytokine level, collectively aggravating disease course and flare-up risk.	27908413
Inflammation	Altered Intercellular Communication	Chronic systematic inflammation has been suggested to be associated with the occurrence and development of cardiovascular events.	27908556
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Low-grade systematic inflammation persists in type 2 diabetes mellitus (T2DM) patients.	27908556
Inflammation, Cerebral Hemorrhage	Altered Intercellular Communication	NLR >2.58 might be useful in predicting the threshold value of cerebral hemorrhage risk in newly diagnosed T2DM patients (area under the curve: .72, 95% CI: .659-.780, P < .001) CONCLUSION: As an indicator of the degree of systematic inflammation, NLR is an independent risk factor of cerebral hemorrhage in T2DM patients.	27908556
APP gene, Inflammation, Aortic Aneurysm, Abdominal, Atherosclerotic lesion	Altered Intercellular Communication	High-mobility group box 1 (HMGB-1) is a key substance mediating inflammation and development of atherosclerotic lesions (ALs), including abdominal aortic aneurysms (AAA).	27908811
Inflammation, Specimen Type - Fistula, Digestive System Fistula	Altered Intercellular Communication	Effect of Oral o3-Polyunsaturated Fatty Acids as a Complement Management to Control Fistula Output and Inflammation in Patients With Digestive Fistula.	27909869
Digestive System Fistula, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	The presence of digestive fistula involves chronic inflammation and fibrosis.	27909869
Inflammation, Aortic Aneurysm, Abdominal, Leukocytes, APP gene, Muscle, Smooth, Vascular	Altered Intercellular Communication	Inflammation with leukocytic infiltration, degradation of extracellular matrix (ECM), and depletion of vascular smooth muscle cells (VSMC) are pathological hallmarks of abdominal aortic aneurysm (AAA).	27910812
Inflammation, Depression, CTCAE, Bipolar Disorder	Altered Intercellular Communication	Depression with inflammation: longitudinal analysis of a proposed depressive subtype in community dwelling older adults.	27911015
Inflammation, Depression, CTCAE	Altered Intercellular Communication	It has been proposed that inflammation may be causally related to depression.	27911015
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Participants with depression and inflammation (C Reactive Protein > 3 mg/l) were compared to those with depression alone.	27911015
Inflammation, Depression, CTCAE	Altered Intercellular Communication	In a longitudinal analysis, depression with associated inflammation was more likely to persist over time.	27911015
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Inflammation either partially or completely mediated the association between medical co-morbidity, body mass index and depression at follow-up.	27911015
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Depression with inflammation was associated with more amotivation, less sadness, greater medical co-morbidity and higher body mass index.	27911015
Immunoglobulin A deficiency (disorder)	Altered Intercellular Communication	Secretory IgA Deficiency in Individual Small Airways Is Associated with Persistent Inflammation and Remodeling.	27911098
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	We examined the relationship between secretory IgA (SIgA) on the mucosal surface of small airways and parameters of inflammation and airway wall remodeling in chronic obstructive pulmonary disease (COPD).	27911098
ARCN1 gene, Immunoglobulin A deficiency (disorder), Inflammation	Altered Intercellular Communication	Our findings support the concept that localized, acquired SIgA deficiency in individual small airways of patients with COPD allows colonizing bacteria to cross the epithelial barrier and drive persistent inflammation and airway wall remodeling, even after smoking cessation.	27911098
Alzheimers Disease	Altered Intercellular Communication	These findings suggest that nitrosylation of VAChT and VGLUT1 may be associated with dysfunctional acetylcholinergic and glutamatergic neurotransmission in Alzheimer's disease.	27911305
Inflammation, Carcinogenesis, Liver and Intrahepatic Biliary Tract Carcinoma	Altered Intercellular Communication	Systemic inflammation is known to promote carcinogenesis in biliary tract cancer (BTC).	27911876
Inflammation	Altered Intercellular Communication	Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are indicative of systemic inflammation.	27911876
Inflammation, Neoplasms	Altered Intercellular Communication	Higher systemic inflammation status also had relation with a primary tumor site (p = 0.003) and higher levels of CEA (p = 0.038).	27911876
Inflammation	Altered Intercellular Communication	Systemic inflammation represented by NLR and PLR, predicts the OS of patients with advanced BTC who are receiving palliative chemotherapy.	27911876
Inflammation	Altered Intercellular Communication	Acute phase Hp level might reflect the severity of oxidative stress during inflammation process.	27913007
Inflammation, Fatigue	Altered Intercellular Communication	Fatigue has been linked to chronic inflammation, and diets high in antioxidant nutrients have been associated with lesser prevalence and severity of fatigue.	27913933
Degenerative polyarthritis	Altered Intercellular Communication	Inflammation of synovial membrane and degeneration of articular cartilage in osteoarthritis (OA) lead to major changes in joint space width (JSW) and biochemical components such as collagen-II telopeptide (CTX-II) and matrix metallo protineases (MMP-3, 8, and 13).	27913970
HD Term Type, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Plasma sRAGE and S100A12 may be weak surrogate markers for predicting all-cause mortality in patients undergoing HD, although S100A12 was partly related to diabetes and inflammation.	27914132
Inflammation, Meningitis	Altered Intercellular Communication	Mediators and Biomarkers of Inflammation in Meningitis: Cytokine and Peptidome Profiling of Cerebrospinal Fluid.	27914455
ARCN1 gene, Inflammation	Altered Intercellular Communication	The purpose of this analysis was to determine if patients with COPD have distinctive symptom profiles and to examine the association of symptom profiles with systemic biomarkers of inflammation.	27914470
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	During vasculitis, activation of the kinin system induces inflammation, whereby the kinin B1-receptor is expressed and activated after ligand binding.	27914700
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Here we determined whether leukocyte-derived microvesicles bear B1-kinin receptors during vasculitis, and if microvesicles transfer functional B1-receptors to recipient cells, thus promoting inflammation.	27914700
Inflammation	Altered Intercellular Communication	Thus, we found a novel mechanism by which microvesicles transfer functional receptors and promote kinin-associated inflammation.	27914700
Inflammation	Altered Intercellular Communication	Patients presented inflammation syndrome and high levels of CXCL12, soluble stem cell factor and granulocyte colony-stimulating factor, whereas granulocyte macrophage colony-stimulating factor was low.	27914820
Inflammation, Uveitis	Altered Intercellular Communication	For patients with uveitis, disease activity (active vs. inactive) and grade of inflammation were recorded according to Standardization of Uveitis Nomenclature criteria.	27914832
Inflammation, Infection	Altered Intercellular Communication	Soluble urokinase-type plasminogen activator receptor (suPAR) is a glycoprotein secreted during inflammation and infections.	27914940
Inflammation, Neoplasms	Altered Intercellular Communication	High levels of inflammation in the tumour centre, but not the periphery were associated with better patient survival (p = 0.001), similar to high counts of intratumoural FoxP3+, CD3+, CD8+ TILs (p = 0.001; p = 0.027; p = 0.038) and a combination of CD3+/CD8+/FoxP3+ TILs, the latter displaying three different prognostic groups (triple high/mixed/triple low; p=0.003).	27916317
Inflammation, Neoplasms	Altered Intercellular Communication	In summary, both high grade total inflammation and high TIL counts in the tumour centre, but not the tumour periphery, show a beneficial prognostic impact on EAC.	27916317
Inflammation, Wounds and Injuries	Altered Intercellular Communication	Inflammation and activation of the innate immune system are often associated with traumatic injury and may involve alterations in toll-like receptor (TLR)-mediated responses.	27916353
Inflammation, Carcinoma of lung, HIV Infections	Altered Intercellular Communication	In our large HIV cohort in the antiretroviral therapy era, we found evidence that dysfunctional immune activation and chronic inflammation contribute to the development of lung cancer in the setting of HIV infection.	27916584
Inflammation	Altered Intercellular Communication	Acetylcholine (ACh) contributes to the modulation of central and peripheral inflammation.	27916909
Inflammation, Brain Injuries, COL4A2 wt Allele, Cerebral Hemorrhage	Altered Intercellular Communication	Inflammation plays a role in secondary brain injury after intracerebral hemorrhage (ICH).	27917647
Inflammatory abnormality of the eye	Altered Intercellular Communication	To report the epidemiology and classification of ocular inflammation at a tertiary eye care center in Singapore.	27918224
Inflammatory abnormality of the eye	Altered Intercellular Communication	The pattern of ocular inflammation in Singapore has similarities with both Western and Asian populations.	27918224
Inflammation, Tissue Factor	Altered Intercellular Communication	The prevalence of trachomatous inflammation - follicular (TF) in children aged 1-9 years was between 0.03% and 8% across the LGAs, with only one LGA (Igabi) having a TF prevalence >=5%.	27918227
Communicable Diseases, Inflammation	Altered Intercellular Communication	Thirty-five age-matched subjects without any infectious diseases or inflammation were selected as controls.	27918431
Renal Insufficiency, Inflammation, Abnormal renal function	Altered Intercellular Communication	Renal dysfunction in HFrEF was associated with both NLR and NGAL levels, but systemic inflammation reflected by NLR seemed to be a more important determinant of progression of kidney dysfunction.	27918494
Pancreatitis, Acute, Inflammation, Metabolic Diseases	Altered Intercellular Communication	Low-grade inflammation persists in patients with acute pancreatitis (AP) after hospital discharge, and is linked to metabolic disorders.	27918953
Inflammation	Altered Intercellular Communication	It may, however, induce complement activation and downstream inflammation due to bio-incompatibility.	27919366
Refractory anemias, Inflammation, Microabscess, Communicable Diseases	Altered Intercellular Communication	Except for microabscess found in one RA patient, all pathological sections showed mild chronic inflammation but no infection.	27919672
Inflammation, Fibrosis Assessment, Heart failure, Atherosclerosis	Altered Intercellular Communication	Heart failure and atherosclerosis share the underlying mechanisms of chronic inflammation followed by fibrosis.	27920122
Inflammation, Atherosclerosis	Altered Intercellular Communication	A highly conserved microRNA (miR), miR-33, is considered as a potential therapeutic target for atherosclerosis because it regulates lipid metabolism and inflammation.	27920122
Inflammation, "Extra-osseous Ewings sarcoma	Altered Intercellular Communication	We hypothesized that one function of eosinophils in EoE might be to regulate the T cell-driven inflammation in the oesophagus.	27921303
Cirrhotic	Altered Intercellular Communication	We conclude that gut-brain axis alterations may be associated with the type of neurobehavioral decline or inflamm-aging in elderly cirrhotic subjects.	27922089
Anomia, Inflammation	Altered Intercellular Communication	Cirrhotics were impaired on non-amnestic and selected amnestic tests, HRQOL and systemic inflammation compared to non-cirrhotics.	27922089
Inflammation, Fibrosis Assessment, Lung diseases	Altered Intercellular Communication	Inflammation is a central contributor to the pathogenesis of cystic fibrosis (CF) pulmonary disease; so limiting the excessive production of inflammatory mediators represents a major therapeutic strategy for slowing the decline in lung function and improving survival.	27922234
Inflammation, Corneal edema, Unspecified visual loss	Altered Intercellular Communication	Diffuse corneal edema and anterior chamber inflammation prohibited any view to the posterior segment to identify the cause of her profound vision loss.	27922461
Inflammation, Primary malignant neoplasm, Neoplasm Metastasis	Altered Intercellular Communication	Matrix metalloproteinase-2 (gelatinase A) is a well-known mediator of cancer metastasis, but it is also thought to be involved in several aspects of cancer development, including cell growth and inflammation.	27922483
Myositis	Altered Intercellular Communication	LDK multifidus specimens revealed diffuse, nonuniform muscular fibers and growth of the interstitium and adipose tissue, with no muscular inflammation.	27922574
Inflammation	Altered Intercellular Communication	The rate of systemic inflammation in FG was 30.71%, which was the highest among three groups (P = 0.042).	27923057
Pain Distress Question, Inflammation, Neoplasms	Altered Intercellular Communication	The authors report the case of a 64-year-old male with a soft tissue mass in his right gluteal area that presented initially with right leg pain, then later with signs of inflammation on the tumor area.	27923374
Menopause	Altered Intercellular Communication	Does Inflammation Mediate Relationships Between Racial Identity and Onset of Menopause Among US Adults?	27924623
Inflammation	Altered Intercellular Communication	The advanced patient age, MCC, PSA, and chronic inflammation may be the important clinical predictors of persistent IDC.	27924790
Cerebral Amyloid Angiopathy, Inflammation	Altered Intercellular Communication	Histopathological examination demonstrated cerebral amyloid angiopathy with perivascular inflammation.	27925301
Inflammation, septic	Altered Intercellular Communication	The declined levels of serum inflammatory cytokines, especially IL-6, improved inflammation status might be one factor of successfully weaning during septic patients on ventilators.	27925446
Inflammation	Altered Intercellular Communication	This result may extend previous knowledge on close interactions between inflammation and arterial stiffening.	27927628
Infarction, Inflammation	Altered Intercellular Communication	Importantly, although there was no correlation with infarct size (r=0.03, p=0.90) or inflammation (C reactive protein, r=-0.20, p=0.38), 18F-fluciclatide uptake was increased in segments displaying functional recovery (TBRmean 0.95+-0.33 vs 0.81+-0.27, p=0.002) and associated with increase in probability of regional recovery.	27927700
Hepatic inflammation, Diabetes Mellitus, Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	HIV/HCV coinfection and elevated interleukin (IL)-18 levels are both associated with enhanced progression of hepatic inflammation and increased risk of diabetes, kidney disease, and cardiovascular disease.	27927859
Inflammation	Altered Intercellular Communication	Regulatory receptors expressed on monocytes and macrophages act to suppress cytokine production, and reduced expression of regulatory receptors may thus promote tissue inflammation.	27929051
Inflammation, Arachnoiditis, Pain Distress Question	Altered Intercellular Communication	Patterns of chronic inflammation in extensively treated patients with arachnoiditis and chronic intractable pain.	27929717
Inflammation, Chronic pain	Altered Intercellular Communication	To use biomarkers to gain insight into and gauge the residual (post-treatment) level of inflammation in two groups of intensively treated patients with severe chronic pain.	27929717
Inflammation, Astrocytoma, Toxoplasmosis	Altered Intercellular Communication	All patients were successfully sampled, and the histological results showed inflammation in 4 cases, toxoplasma gondii infection in 1 case, astrocytoma in 1 case, and abscess in 1 case.	27930545
Dilated Cardiomyopathy Pathway, Myocarditis	Altered Intercellular Communication	Comparison of Ventricular Inducibility with Late Gadolinium Enhancement and Myocardial Inflammation in Endomyocardial Biopsy in Patients with Dilated Cardiomyopathy.	27930686
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We could not find a significant association between inducibility and the degree of cardiac inflammation and fibrosis in non-site directed routine right ventricular endomyocardial biopsy.	27930686
Inflammation, Fibrosis Assessment, Ventricular arrhythmia	Altered Intercellular Communication	The presence of myocardial fibrosis or inflammation in undirected endomyocardial biopsy does not seem to be sufficient to predict future ventricular arrhythmias.	27930686
Inflammation	Altered Intercellular Communication	Endogenous hydrogen sulfide (H2S) has recently been shown to play an important role in inflammation, but the role of endogenous H2S in the human gingival tissue is unknown.	27930932
Chronic liver disease, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Overall 20 (87%) featured chronic liver disease characterized by a chronic inflammation and/or a significant portal fibrosis on histology.	27931086
Inflammation, Invasive Malignant Neoplasm, Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	Metalloproteinases (MMPs) are relevant modulators of inflammation, tumor microenvironment, cancer invasion and metastasis.	27931798
Axonal degeneration, Inflammation, Sensory neuropathy	Altered Intercellular Communication	Electrophysiological studies indicated primary axonal degeneration of peripheral motor and sensory fibers without inflammation.	27932182
Pain Distress Question, Inflammation	Altered Intercellular Communication	Overall both topical treatments were effective in alleviating pain and inflammation, as evidenced by decreases in pain and inflammation scores within 3 days after treatment initiation.	27933598
Pain Distress Question, Inflammation	Altered Intercellular Communication	DHEP mouthwash was at least as effective as diclofenac mouth-wash at alleviating pain and inflammation symptoms and is well tolerated in patients with painful inflammatory conditions of the oral cavity.	27933598
Pain Distress Question, Inflammation	Altered Intercellular Communication	DHEP mouthwash was at least as effective as diclofenac mouth-wash at alleviating pain and inflammation symptoms and is well tolerated in patients with painful inflammatory conditions of the oral cavity.	27933598
Inflammation, Chlamydia, Hypertrophy	Altered Intercellular Communication	Role of Chlamydia pneumoniae in the pathogenesis of hypertrophy and adenoid tissue inflammation in children.	27935539
Inflammation, Chlamydia, Hypertrophy of adenoids	Altered Intercellular Communication	A tropism to epithelial cells and lymphocytes, an inhibition of apoptosis in host cells, an ability to occurrence in persistent form resistant to antibiotic treatment are the features of Chlamydia pneumoniae, which can have connection with chronic inflammation of an adenoid tissue and adenoid hypertrophy.	27935539
Inflammation, Epithelial cyst	Altered Intercellular Communication	The histopathological findings confirm the diagnosis of an epidermoid cyst, characterized by the presence of: (I) a cyst cavity lined by stratified squamous epithelium with keratinization on the surface; and (II) connective tissue with a mild inflammation.	27935912
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	MAP3K19 Is Overexpressed in COPD and Is a Central Mediator of Cigarette Smoke-Induced Pulmonary Inflammation and Lower Airway Destruction.	27935962
ARCN1 gene, Respiratory physiology, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation and lung inflammation resulting in a progressive decline in lung function whose principle cause is cigarette smoke.	27935962
Inflammation, Impaired cognition, ETV3 wt Allele	Altered Intercellular Communication	MetS patients had high levels of inflammation and a 3.542-fold increased odds ratio (OR) for cognitive impairment [95% confidence interval (CI): 1.972-6.361].	27936074
Acute inflammation	Altered Intercellular Communication	This suggests that, if disturbances in melatonin secretion occur, these might occur after surgery due to postoperative inflammation.	27936113
Inflammation, Burn injury	Altered Intercellular Communication	Microvesicles are cell-derived signaling particles emerging as important mediators and biomarkers of systemic inflammation, but their production in severe burn injury patients has not been described.	27936199
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Comparison of different contouring definitions of the rectum as organ at risk (OAR) and dose-volume parameters predicting rectal inflammation in radiotherapy of prostate cancer: which definition to use?	27936891
Inflammation	Altered Intercellular Communication	Acute or subacute rectal inflammation occurred in 69 (71.9%) patients in Cohort 1 and in 43 (70.5%) in Cohort 2.	27936891
Peripheral Vascular Diseases, Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Strong evidence implicates inflammation in the development of atherosclerotic heart disease but less is known about peripheral arterial disease (PAD).	27938334
Crohn Disease, Specimen Type - Fistula, Inflammation	Altered Intercellular Communication	Crohn's disease (CD) is characterized by transmural inflammation of the gastrointestinal tract, which predisposes to the formation of fistula.	27939339
Inflammation, Arthritis, Hypocalcemia	Altered Intercellular Communication	After 5 days, she had arthritis of the right wrist, laboratory evidence of systemic inflammation, and hypocalcemia.	27939801
Inflammation, Hypocalcemia	Altered Intercellular Communication	The features were similar to those in our patients, with a short time to onset, systemic inflammation in many cases, a tendency toward hypocalcemia, and radiographs that often showed evidence of CPDD.	27939801
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The relationship between systemic inflammation and stoma formation following anterior resection for rectal cancer: A cross-sectional study.	27940290
Keratitis, Corneal edema	Altered Intercellular Communication	Because corneal inflammation and corneal edema improved, the protruding structures and high-intensity regions of posterior corneal images were resolved after a course of antiviral treatment.	27941387
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is more prevalent in HIV-infected individuals and is associated with persistent inflammation.	27941393
Cyst, Inflammation, Fibrous	Altered Intercellular Communication	Following excision, histology showed a cyst that contained keratin and lanugo hairs in its lumen with sebaceous glands and chronic inflammation in its fibrous wall.	27941469
Inflammation	Altered Intercellular Communication	iTRAQ-based proteomic profiling reveals that complement and coagulation cascades and inflammation may play important roles in the pathogenesis of RRDCD.	27941623
Inflammation, Demyelination, N-nitrosomorpholine	Altered Intercellular Communication	Hydroxycholesterols (OHCs), metabolites of CNS cholesterol, are involved in diverse cellular responses to inflammation and demyelination, and may also be involved in the pathogenesis of NMO.	27942009
Inflammation, Endothelial dysfunction, Chronic Kidney Diseases	Altered Intercellular Communication	Chorioretinal thinning in chronic kidney disease links to inflammation and endothelial dysfunction.	27942587
Arterial Stiffness, Inflammation	Altered Intercellular Communication	Finally, choroidal thinning was associated with renal histological inflammation and arterial stiffness.	27942587
Arterial Stiffness, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Similarly, the associations with arterial stiffness, inflammation, and endothelial dysfunction warrant further examination.	27942587
Inflammation, Malnutrition	Altered Intercellular Communication	Low circulating coenzyme Q10 during acute phase is associated with inflammation, malnutrition, and in-hospital mortality in patients admitted to the coronary care unit.	27942805
Poi serotype, Inflammation	Altered Intercellular Communication	The aim of this study was to investigate the relation of POI with inflammation and AL after colorectal resection.	27943617
Inflammation	Altered Intercellular Communication	The SASP secreted by accumulated senescent cells during old age has been related to local inflammation that leads to cellular transformation and therefore may be supporting the inflammaging process.	27951455
Inflammation	Altered Intercellular Communication	The SASP secreted by accumulated senescent cells during old age has been related to local inflammation that leads to cellular transformation and therefore may be supporting the inflammaging process.	27951455
Inflammation, Fatty degeneration	Altered Intercellular Communication	There were significant and strong associations between serum miR-122 ratio (ratio of level at second biopsy to that at first biopsy) and changes in histopathological scores (of steatosis, lobular inflammation, and stage).	27955628
Refractory anemias, Rheumatoid Arthritis, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	Diseases associated with human cartilage, including rheumatoid arthritis (RA) and osteoarthritis (OA) have manifested age, mechanical stresses and inflammation as the leading risk factors.	27955675
Chronic cerebrovascular accident, Inflammation	Altered Intercellular Communication	RT in chronic stroke induces changes in key skeletal muscle regulators of metabolism, without effecting circulating inflammation.	27955950
Arteritis	Altered Intercellular Communication	Coronary arterial inflammation (18F-fluorodeoxyglucose uptake, expressed as target-to-background ratio) was assessed in the left main coronary artery (LMCA).	27956407
Inflammation, Sympathetic Nervous System, Hypertension, CTCAE	Altered Intercellular Communication	Overactivation of renal sympathetic nervous system and low-grade systemic inflammation are common features of hypertension.	27956575
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	However, we propose that keloids and hypertrophic scars are simply manifestations of the same skin FPD and differ only in the degree of endothelial dysfunction and therefore inflammation.	27959277
Schizophrenia	Altered Intercellular Communication	Cortical grey matter volume reduction in people with schizophrenia is associated with neuro-inflammation.	27959331
Deficit, Schizophrenia, negative regulation of urine volume	Altered Intercellular Communication	Cortical grey matter volume deficits and neuro-inflammation exist in patients with schizophrenia, although it is not clear whether elevated cytokines contribute to the cortical volume reduction.	27959331
Inflammation, Rheumatoid Arthritis, Pain Distress Question	Altered Intercellular Communication	Discordant inflammation and pain in early and established rheumatoid arthritis: Latent Class Analysis of Early Rheumatoid Arthritis Network and British Society for Rheumatology Biologics Register data.	27964757
Pain Distress Question, Central pain, Inflammation	Altered Intercellular Communication	In latent class analysis, we used variables related to pain, central pain mechanisms or inflammation (pain, vitality, mental health, erythrocyte sedimentation rate, swollen joint count, tender joint count, visual analogue scale of general health).	27964757
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	A high neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation and is associated with poor survival in localized or metastatic cancer.	27964892
Primary malignant neoplasm	Altered Intercellular Communication	DNA Methylation-Derived Neutrophil-to-Lymphocyte Ratio: An Epigenetic Tool to Explore Cancer Inflammation and Outcomes.	27965295
Inflammation	Altered Intercellular Communication	Although high-mobility group box 1 (HMGB1) is involved in many aspects of inflammation, its role in sepsis-induced immune suppression remains unclear.	27965385
Inflammation	Altered Intercellular Communication	Vitamin D supplementation may contribute to reduced inflammation and improved lung function in CF.	27966575
Communicable Diseases, Inflammation	Altered Intercellular Communication	Furthermore, S2V was less virulent than the prototype strain VACV-Western Reserve (WR) in a murine model of intradermal infection, producing a tiny lesion with virtually no surrounding inflammation.	27973399
Inflammation, Atherosclerotic lesion	Altered Intercellular Communication	Vascularization was also increased in the upstream regions of advanced atherosclerotic lesions compared with downstream regions (4.6 vs. 1.4 vessels/mm2, p = 0.001) and was associated with intra-plaque hemorrhage and inflammation.	27973542
Inflammation	Altered Intercellular Communication	Vascularization is increased in the upstream regions of both early and advanced plaques and is in advanced lesions mainly driven by inflammation.	27973542
Airway structure	Altered Intercellular Communication	Fractional concentration of exhaled nitric oxide (FeNO) is recommended by the American Thoracic Society (ATS) as a noninvasive biomarker of airway inflammation.	27973944
Cessation of life	Altered Intercellular Communication	Tunneling nanotubes (TNTs) are intercellular communication structures involved in transport of cellular contents and pathogens, also demonstrated to play a role in both cell death modulation and chemoresistance.	27974700
Delirium	Altered Intercellular Communication	Simple enhancement of cholinergic neurotransmission may not be sufficient to treat delirium.	27974719
Prolactin Release-Inhibiting Hormone, Inflammation, Hyperpigmentation	Altered Intercellular Communication	Postinflammatory hyperpigmentation (PIH) is an acquired hyperpigmentation that involves areas of prior cutaneous inflammation.	27976510
Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	Rheumatoid arthritis (RA) is characterized by autoimmune chronic joint inflammation, which is worsened by mechanical stress.	27976695
Inflammation, Fibrosis Assessment, Pneumoconiosis	Altered Intercellular Communication	Inhaled dust leads to inflammation and fibrosis in the lungs, and coal workers' pneumoconiosis can be a debilitating disease.	27977638
Inflammation, Proteobacteria, Actinobacteria phylum	Altered Intercellular Communication	Inflammation explained 30-98% of the observed associations between levels of Actinobacteria, Proteobacteria or Firmicutes and insulin resistance (p-values < 0.05).	27978598
Inflammation	Altered Intercellular Communication	Eighteen individual taxa were associated with inflammation (p < 0.05) and 22 with insulin resistance (p < 0.05).	27978598
Multiple Organ Failure, Inflammation, Sepsis, Dyslipidemias, Liver Dysfunction, Diabetes Mellitus, Hypocalcemia, Hypokalemia, Systemic Inflammatory Response Syndrome, Chronic Kidney Diseases	Altered Intercellular Communication	In this study, systemic inflammation, sepsis, systemic inflammatory response syndrome (SIRS), multiple organic failure (MOF), chronic renal failure, liver dysfunction, mechanical ventilation, diabetes, dyslipidemia and impaired ion homeostasis (hypocalcaemia, hypokalemia) were associated with CIP.	27978832
Inflammation, Heart failure	Altered Intercellular Communication	Although heightened inflammation and autoimmune responses have been well described in patients with heart failure, the role of cell-mediated immune function in the pathogenesis and progression of heart failure is unclear.	27979039
Inflammation, Psoriasis, Inflammatory dermatosis	Altered Intercellular Communication	Psoriasis is a chronic inflammatory skin disease characterized by epidermal hyperproliferation and altered keratinocyte differentiation and inflammation and is caused by the interplay of genetic and environmental factors.	27980695
Inflammatory Bowel Diseases, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Both chronic inflammation and reduced immunosurveillance contribute to malignancy development in inflammatory bowel disease (IBD).	27981298
Inflammation, Hepatobiliary Disorder, Fibrosis Assessment	Altered Intercellular Communication	Histological severity of liver disease (inflammation, ballooning, and fibrosis) was not associated with the amount of IHTG content.	27981615
physiopathological, Decreased Libido	Altered Intercellular Communication	The "older" vignette's dysfunction was more likely to be attributed to hormonal changes, health problems and decreased sexual desire.	27981728
Juvenile-Onset Still Disease	Altered Intercellular Communication	Adult-onset Still's disease (AOSD) is an uncommon inflammatory condition of unknown origin.	27981819
Cereals, Having administered, Inflammation	Altered Intercellular Communication	Administered concurrently with a glucose bolus, the source of whole grains did not attenuate the post-prandial response of markers of glucoregulation and insulin sensitivity, inflammation, nor vascular remodeling compared to the refined grain control.	27983687
ARCN1 gene, neutrophilic, Asthma, Inflammation	Altered Intercellular Communication	The aim of this study was to analyze the neutrophilic and eosinophilic airway and systemic inflammation as the phenotypic characterization of patients with asthma and COPD.	27983888
ARCN1 gene, Airway structure	Altered Intercellular Communication	Asthma and COPD can be differentiated based on eosinophilic/neutrophilic systemic or airway inflammation with unsatisfactory efficiency.	27983888
Community acquired pneumonia	Altered Intercellular Communication	Community-acquired pneumonia (CAP) is characterized as an acute inflammation of the lung associated with the activation of macrophages and neutrophils.	27983998
Pneumonitis	Altered Intercellular Communication	Intercellular adhesion molecule-1 (ICAM-1) is an essential adhesion molecule involved in immune cell recruitment in lung inflammation.	27983998
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	NADPH oxidase 4 regulates vascular inflammation in aging and atherosclerosis.	27986445
vascular inflammations, physiopathological, Atherosclerosis	Altered Intercellular Communication	We recently reported that increased NADPH oxidase 4 (NOX4) expression and activity during aging results in enhanced cellular and mitochondrial oxidative stress, vascular inflammation, dysfunction, and atherosclerosis.	27986445
Radiculitis, Palsy	Altered Intercellular Communication	Different hypotheses have been proposed for the pathophysiology of posterior interosseous nerve (PIN) palsy, namely compression, nerve inflammation, and fascicular constriction.	27986526
Inflammation, COL4A2 wt Allele, Cerebral Hemorrhage	Altered Intercellular Communication	Reducing excessive inflammation is beneficial for the recovery from intracerebral hemorrhage (ICH).	27986908
Inflammatory, Inflammation	Altered Intercellular Communication	These results suggested that A20 is involved in regulating ICH-induced inflammatory injury in both the central and peripheral system and that A20 reduces ICH-induced inflammation by regulating TRAF6 polyubiquitination.	27986908
Inflammation, Prostate Imaging-Reporting and Data System	Altered Intercellular Communication	Inflammation was found in 36 (58%) PIRADS 3 lesions, 24 (39%) PIRADS 4 lesions and 2 (3%) PIRADS 5 lesions on pre biopsy MRI evaluation.	27987276
Inflammation, Prostate Imaging-Reporting and Data System	Altered Intercellular Communication	In our series, biopsies which showed inflammation had a radiological appearance on mpMRI more likely of a PIRADS 3 or 4 lesions with only 3% of PIRADS 5 biopsies showing inflammation.	27987276
Inflammation, Electrocardiogram: myocardial infarction (finding), Blood Clot	Altered Intercellular Communication	To compare angiographic and optical coherence tomography (OCT) data pertinent to thrombi, along with the histologic characteristics of aspirated thrombi in patients presenting with ST elevation myocardial infarction (STEMI) with or without inflammation, as assessed by C-reactive protein (CRP) and myeloperoxidase (MPO).	27988513
Inflammation, Psoriasis, Arthritis, Psoriatic	Altered Intercellular Communication	Among patients with psoriasis no significant correlations with the disease activity and inflammation markers were observed and only patients with psoriatic arthritis had significantly higher CER total concentration.	27988894
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Surgery should be as close as possible to displacement in order to minimise mucosal inflammation and to prevent unnecessary manipulation during surgical removal.	27990509
Malignant Peripheral Nerve Sheath Tumor, Inflammation, Myeloproliferative disease	Altered Intercellular Communication	It has been reported that chronic inflammation may be an important driving force for myeloproliferative neoplasms (MPNs).	27990849
Inflammation, Thrombocytosis	Altered Intercellular Communication	Therefore, we hypothesized that as an important inflammation regulator, TIM-3 may be involved in essential thrombocythaemia (ET).	27990849
Edema	Altered Intercellular Communication	Muscle oedema on fat-suppressed MRI sequences is thought to represent active inflammation.	27991408
Inflammation	Altered Intercellular Communication	Systemic inflammation has been linked to suppressed CYP3A(4) activity.	27991741
Inflammation, Comorbidity	Altered Intercellular Communication	There were no differences in nutrition, comorbidity, and inflammation indices among the patients with different non-HDL groups.	27992532
Nephritis	Altered Intercellular Communication	These results suggest that urine OPN N-half concentration reflects renal inflammation.	27992535
Uremia, Inflammation, Atherosclerosis	Altered Intercellular Communication	In this study, we investigated the expression of Lp-PLA2 on leucocytes and different monocyte subpopulations and their possible role in uremia, inflammation, and atherosclerosis.	27992874
Allergic sensitization, Inflammation, Noncommunicable Diseases	Altered Intercellular Communication	Systemic low-grade inflammation has been demonstrated in a range of the frequent noncommunicable diseases (NCDs) proposing a shared mechanism, but is largely unexplored in relation to allergic sensitization.	27992959
Allergic sensitization, Inflammation	Altered Intercellular Communication	Elevated hs-CRP is associated with allergic sensitization in school-aged children suggesting systemic low-grade inflammation as a phenotypic characteristic of this early-onset NCD.	27992959
Myeloid	Altered Intercellular Communication	Nutritional Wheat Amylase-Trypsin Inhibitors Promote Intestinal Inflammation via Activation of Myeloid Cells.	27993525
Pancreatitis	Altered Intercellular Communication	Orally ingested ATIs are largely resistant to proteases and heat, and increase intestinal inflammation by activating gut and mesenteric lymph node myeloid cells.	27993525
Inflammation, HDL Phospholipid Measurement, ETV3 wt Allele	Altered Intercellular Communication	Low HDL-P is independently associated with incident MetS after adjustment for traditional risk factors, lipid parameters, adiposity, inflammation, and markers of insulin resistance.	27993539
Pigmentation, Retinitis Pigmentosa, Vitreous inflammatory cells	Altered Intercellular Communication	Twenty-five patients were identified by characteristic symptoms (abrupt onset of photopsias, followed by large scotomata at or connected to the blind spot), ocular findings (paucity of pigmentary changes with no sign of vitreous inflammation and abnormal electroretinogram in at least 1 eye), and a negative family history for retinitis pigmentosa.	27993590
Inflammation, Calcification of coronary artery, Carotid Intima-Media Thickness, Atherosclerosis, Peripheral Vascular Diseases	Altered Intercellular Communication	This study assesses the impact of SHS on inflammation and atherosclerosis (carotid intima-media thickness, coronary artery calcification, and peripheral arterial disease).	27993830
Inflammation, Carotid Intima-Media Thickness	Altered Intercellular Communication	Urinary cotinine was not associated with inflammation or carotid intima-media thickness.	27993830
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	Despite limited exposure assessment, this study supports the association of SHS exposure with inflammation and peripheral arterial disease.	27993830
Adenomatous polyp of colon, Chronic Kidney Diseases, Diabetes Mellitus	Altered Intercellular Communication	Adenomatous Colon Polyps in Diabetes: Increased Prevalence in Patients with Chronic Kidney Disease and Its Association with Parathyroid Hormone.	27993873
Inflammation, Coronary microvascular dysfunction	Altered Intercellular Communication	Uric Acid Is Associated With Inflammation, Coronary Microvascular Dysfunction, and Adverse Outcomes in Postmenopausal Women.	27993955
Inflammation, Hyperlipidemia	Altered Intercellular Communication	Association of Beta-2 Microglobulin with Inflammation and Dislipidemia in High-Flux Membrane Hemodialysis Patients.	27994294
Bone Diseases, Inflammation, Dyslipidemias	Altered Intercellular Communication	In high-flux membrane hemodialysis patients, we observed a significant relationship of b2M with dyslipidemia and mineral bone disorders, but there was no correlation with inflammation.	27994294
Inflammatory abnormality of the eye, Dislocations	Altered Intercellular Communication	Five weeks later, ocular inflammation subsided following posterior dislocation of the cataractous lens, thus revealing the error in our initial diagnosis.	27994397
Refractory anemias, vascular inflammations	Altered Intercellular Communication	Accordingly, resistive index (RI) on spectral Doppler (sD) US provides a quantitative analysis of vascular inflammation, but its utility in the evaluation of RA activity has not been established.	27995383
Inflammation	Altered Intercellular Communication	The pixel-based CEUS assessment is a truly measure synovial inflammation, as a useful tool to develop quantitative imaging biomarker for monitoring target therapeutics in PsA.	27995384
Inflammation	Altered Intercellular Communication	In summary, our results demonstrate the role of inflammation and oxidative stress in age-related changes of immune cell survival factors in the BM, suggesting that antioxidants may be beneficial in counteracting immunosenescence by improving immunological memory in old age.	27995612
Airway structure	Altered Intercellular Communication	Fractional exhaled nitric oxide (FENO) levels were measured to assess airway inflammation.	27996287
Inflammation, Biliary calculi, Mirizzi Syndrome, Cholecystolithiasis, MS gene	Altered Intercellular Communication	Mirizzi syndrome (MS) is a rare complication of cholecystolithiasis that causes compacted gallstones and is often accompanied by severe inflammation of Calot's triangle.	27996365
Neoplasms	Altered Intercellular Communication	DAAs Rapidly Reduce Inflammation but Increase Serum VEGF Level: A Rationale for Tumor Risk during Anti-HCV Treatment.	27997563
Inflammation, Muscular Dystrophy	Altered Intercellular Communication	The results indicate that genetic reduction of p65 levels diminished chronic inflammation in dystrophic muscle, thus leading to amelioration of muscle pathology and improved muscle physiological function.	27997693
Degenerative polyarthritis, Inflammation, Synovitis	Altered Intercellular Communication	Associations Between Clinical Evidence of Inflammation and Synovitis in Symptomatic Knee Osteoarthritis: A Cross-Sectional Substudy.	27998036
Degenerative polyarthritis, Arthritis	Altered Intercellular Communication	Painful knee osteoarthritis (KOA) has been associated with joint inflammation.	27998036
Inflammation, Clinical Events Domain	Altered Intercellular Communication	This study examined the relationship between clinical and functional markers of localized knee inflammation and CE MRI-based synovial scores.	27998036
Inflammation, Pain Distress Question, Stiffness, Sore to touch, effusion	Altered Intercellular Communication	In this cross-sectional substudy, associations between validated MRI-based semiquantitative synovial scores of the knee and the following markers of inflammation were investigated: self-reported pain and stiffness, effusion, warmth, joint line tenderness, erythrocyte sedimentation rate, radiographic severity, and functional ability tests.	27998036
Suppuration, Pain Distress Question, Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	A 78-year-old woman of African descent presented with pain, inflammation, suppuration, ulceration, and deformation of digits of all four limbs.	27998311
Inflammation, Periprosthetic osteolysis	Altered Intercellular Communication	Evidence suggests that wear particles induce inflammation causing periprosthetic osteolysis contributing to implant loosening with wear rates of 0.05 mm/y were considered safe.	27998657
Osteoblastoma, Bone lesion, Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The final diagnosis was established by CT-guided biopsy of both the bone lesion and the paraspinal soft tissue, which excluded malignancy and revealed an osteoblastoma surrounded by plasma cell-rich chronic inflammation.	27999873
Cerebral Amyloid Angiopathy, "Alzheimers Disease", Inflammation, Cerebral microbleeds	Altered Intercellular Communication	Comparison of cerebrospinal fluid profiles in Alzheimer's disease with multiple cerebral microbleeds and cerebral amyloid angiopathy-related inflammation.	28000005
Cerebral Amyloid Angiopathy, Inflammation, "Alzheimers Disease", Hyperintensity of cerebral white matter on MRI, Data types - Address, Cerebral microbleeds	Altered Intercellular Communication	Brain magnetic resonance imaging (MRI) of patients with Alzheimer's disease (AD) sometimes reveals multiple cerebral microbleeds (CMBs) and confluent white matter hyperintensities (WMHs) similar to those observed in cerebral amyloid angiopathy-related inflammation (CAA-I).	28000005
Gastrointestinal inflammation	Altered Intercellular Communication	These drugs have led to prolonged survival but can also result in autoimmune-type side effects, including gastrointestinal inflammation.	28000302
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Dipeptidyl peptidase-4 (DPP4) is an important regulator of incretins and inflammation, and it is involved in the pathophysiological process of myocardial infarction (MI).	28000723
Squamous cell carcinoma of esophagus	Altered Intercellular Communication	Systemic Immune-Inflammation Index Predicts Prognosis of Patients with Esophageal Squamous Cell Carcinoma: A Propensity Score-matched Analysis.	28000729
Neoplasms	Altered Intercellular Communication	Systemic immune-inflammation index (SII), based on peripheral lymphocyte, neutrophil, and platelet counts, was recently investigated as a prognostic marker in several tumors.	28000729
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	These findings suggest that long-term lymphatic volume overload can induce chronic tissue inflammation, progressive fibrosis, impaired homeostasis, altered remodelling of adipose tissue, impaired regenerative capacity and immunological dysfunction.	28000916
Inflammation	Altered Intercellular Communication	As eosinophils typically accumulate at sites that are relatively hypoxic, particularly during periods of inflammation, these findings may have important implications to understanding the behaviour of these cells in vivo.	28000962
Morphology Findings Domain, Inflammation	Altered Intercellular Communication	This case enlights intriguing links between adipogenesis, inflammation and dysmorphology.	28002528
Inflammation, Hamartoma	Altered Intercellular Communication	From a practical point of view, finding and treating an over-imposed inflammation could help limit damage in a hamartomatous syndrome.	28002528
Inflammatory disorder	Altered Intercellular Communication	Toll-like receptor 4 (TLR4) is a key modulator in many inflammation-related diseases.	28002812
Inflammation	Altered Intercellular Communication	Our data provide evidence that polySia avDP20 ameliorates laser-induced damage in the retina and thus is a promising candidate to prevent AMD-related inflammation and angiogenesis.	28003336
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Inflammation plays a crucial role in the pathogenesis of stroke.	28004340
methyldopa, Inflammation	Altered Intercellular Communication	Amyloid b (Ab)-induced chronic inflammation is believed to be a key pathogenic process in early-stage age-related macular degeneration (AMD).	28004443
ARCN1 gene, Inflammation	Altered Intercellular Communication	As COPD is associated with systemic inflammation, we determined whether smoking status is related to serum levels of matrix metalloproteinase-9 (pro- and active MMP-9), neutrophil gelatinase-associated lipocalin (NGAL) and the proMMP-9/NGAL complex in patients with COPD.	28004483
ARCN1 gene, Inflammation	Altered Intercellular Communication	Our results suggest that associated serum levels of proMMP-9, NGAL, proMMP-9/NGAL and NE may reflect the state of systemic inflammation in COPD related to cigarette smoking.	28004483
Coughing, Acid reflux, Bronchial Hyperreactivity, Airway structure	Altered Intercellular Communication	Chronic cough is one of the most common clinical problems and it may be secondary to different stimuli and diseases, including low-level physical and chemical stimulation of the esophageal-bronchial reflex, suggestive of cough-reflex hyperresponsiveness, in patients with gastroesophageal reflux; however, it is still debated whether gastroesophageal reflux could induce airway inflammation and acidification.	28004646
Coughing, Inflammation, Acid reflux	Altered Intercellular Communication	This study adds knowledge on possible mechanisms related to chronic cough associated with gastroesophageal reflux, which seems to be strictly dependent on airway acidification and the production of Cys-LTs, therefore suggesting an underlying neurogenic inflammation with tachykinins involvement.	28004646
Autoimmune Diseases, Inflammation, Rheumatoid Arthritis, Refractory anemias	Altered Intercellular Communication	Th17 and TfH cells are thought to promote tissue inflammation and autoantibody production, respectively, in autoimmune diseases including rheumatoid arthritis (RA).	28004828
Inflammation, Intervertebral Disc Degeneration	Altered Intercellular Communication	Inflammation is thought to have a major role in the pathogenesis of disc degeneration.	28005398
Airway structure, Fibrosis Assessment	Altered Intercellular Communication	Digitoxin for Airway Inflammation in Cystic Fibrosis: Preliminary Assessment of Safety, Pharmacokinetics, and Dose Finding.	28006108
Airway structure, Communicable Diseases, Fibrosis Assessment, Colonization	Altered Intercellular Communication	Cystic fibrosis (CF) lung disease progresses by a combination of airway inflammation, bacterial colonization, and infection.	28006108
Sepsis, Cessation of life, Cardio-Renal Syndrome, Inflammation	Altered Intercellular Communication	Cardiorenal Syndrome Type 5 in Sepsis: Role of Endotoxin in Cell Death Pathways and Inflammation.	28006779
Cell Death, Inflammation, septic	Altered Intercellular Communication	In this study, we investigated the possible relationship between endotoxin levels, renal cell death and inflammation in septic patients with CRS Type 5.	28006779
Inflammation, Apoptosis	Altered Intercellular Communication	Furthermore, this study highlights the presence of renal apoptosis, the immune deregulation and the strong inflammation in CRS Type 5 patients, especially in those with high endotoxin activity.	28006779
Pancreatitis, Acute, Pancreatitis	Altered Intercellular Communication	The predictive accuracy of individual markers, extrapancreatic inflammation on computed tomography (EPIC), acute physiology and chronic health evaluation II (APACHE II), and bedside index for severity in acute pancreatitis (BISAP) scores were measured using the area under the receiver operating characteristic curve (AUROC).	28007685
Kidney Failure, Chronic, vascular inflammations	Altered Intercellular Communication	Effect of omega-3 fatty acid supplementation on serum lipids and vascular inflammation in patients with end-stage renal disease: a meta-analysis.	28008943
Kidney Failure, Chronic, vascular inflammations	Altered Intercellular Communication	However, this association in patients with end-stage renal disease (ESRD) remains controversial prompting the need for investigation into the role of O3FAs on serum lipids and vascular inflammation markers.	28008943
Kidney Failure, Chronic, vascular inflammations	Altered Intercellular Communication	PubMed, EmBase, and the Cochrane Library were searched to identify randomized controlled trials (RCTs) focused on serum lipids and vascular inflammation markers in patients with ESRD.	28008943
Kidney Failure, Chronic, vascular inflammations	Altered Intercellular Communication	O3FA supplementation is associated with lower several serum lipids and vascular inflammation markers in patients with ESRD.	28008943
Inflammation	Altered Intercellular Communication	The Toll-like receptor plays an essential role in controlling immunity and inflammation.	28009434
Pneumonitis	Altered Intercellular Communication	We aimed to identify the role of the enzyme acid sphingomyelinase in the aging of stored units of packed red blood cells (pRBCs) and subsequent lung inflammation after transfusion.	28009749
Pneumonitis	Altered Intercellular Communication	Large volume pRBC transfusions are associated with multiple adverse clinical sequelae, including lung inflammation.	28009749
Pneumonitis	Altered Intercellular Communication	Microparticles are formed in stored pRBCs over time and have been shown to contribute to lung inflammation after transfusion.	28009749
Pneumonitis	Altered Intercellular Communication	Transfusion of aged pRBCs or microparticles isolated from aged blood into mice caused lung inflammation.	28009749
Inflammation, Carcinogenesis	Altered Intercellular Communication	INTRODUCTION Myeloid-derived suppressor cells (MDSCs) have the potent ability to suppress T-cell function, and are important in the regulation of chronic inflammation and carcinogenesis.	28009997
ARCN1 gene, Inflammation	Altered Intercellular Communication	CONCLUSIONS MDSCs are present in human lung microenvironment and may be involved in local inflammation in COPD.	28009997
ARCN1 gene, Inflammation	Altered Intercellular Communication	Future studies should focus on a detailed assessment of MDSCs in local and systemic inflammation in COPD.	28009997
Carcinogenesis, Hepatitis, fibrogenesis	Altered Intercellular Communication	During liver inflammation, triggering fibrogenesis and carcinogenesis immune cells play a pivotal role.	28011329
Liver carcinoma, Hepatitis, Chronic, FAM126A gene	Altered Intercellular Communication	In the present study we investigated the role of CCL5 in human and in murine models of chronic liver inflammation leading to hepatocellular carcinoma (HCC) development.	28011329
Chronic liver disease, Inflammation, Lymphoproliferative Disorder of the Skin, FAM126A gene	Altered Intercellular Communication	CCL5 expression and its receptors were studied in well-defined patients with chronic liver disease (CLD) and in two murine inflammation based HCC models.	28011329
Inflammation, Fibrosis Assessment, Neoplasms	Altered Intercellular Communication	The role of CCL5 in inflammation, fibrosis, tumor initiation and progression was analyzed in different cell populations of NEMODhepa/CCL5-/- animals and after bone marrow transplantation (BMT).	28011329
Cardiac Hypertrophy, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Transgenic overexpression of macrophage matrix metalloproteinase-9 exacerbates age-related cardiac hypertrophy, vessel rarefaction, inflammation, and fibrosis.	28011588
Inflammation	Altered Intercellular Communication	This led to a mismatch in the muscle-to-vessel ratio and resulted in increased cardiac inflammation.	28011588
TG gene, Inflammation	Altered Intercellular Communication	The increase in cardiac inflammation resulted in greater accumulation of interstitial collagen in TG (P < 0.05).	28011588
Cardiac Hypertrophy, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	In conclusion, overexpression of MMP-9 in macrophages resulted in exacerbated cardiac hypertrophy in the setting of vessel rarefaction, which resulted in enhanced inflammation and fibrosis to augment the cardiac-aging phenotype.	28011588
Cardiac Hypertrophy, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	We found that an elevation in macrophage-derived MMP-9 induced a greater age-dependent cardiac hypertrophy and vessel rarefaction phenotype, which enhanced cardiac inflammation and fibrosis.	28011588
Inflammation	Altered Intercellular Communication	In 21 patients undergoing carotid endarterectomy, carotid inflammation was evaluated by both FDG positron emission/computed tomography (FDG-PET/CT) imaging and MWR measurements.	28011672
Inflammation	Altered Intercellular Communication	Carotid inflammation was assessed by PET/CT as target-to-background ratio (TBR) by obtaining measurements in consecutive axial slices 2 cm below to 2 cm above the carotid bifurcation.	28011672
Ischemia, vascular inflammations, Endothelial dysfunction	Altered Intercellular Communication	We hypothesised that patterns of circulating biomarkers that reflect the various pathophysiological components of CAD, such as distorted lipid metabolism, vascular inflammation, endothelial dysfunction, increased thrombogenicity and ischaemia, diverge in the days to weeks before a coronary event.	28011810
Inflammation, Fibrosis Assessment, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Chronic inflammation in the atrial myocardium was shown to play an important role in the development of atrial fibrosis in patients with atrial fibrillation (AF).	28011843
Inflammation, Fibrosis Assessment, Cardiovascular system	Altered Intercellular Communication	Histological signs of chronic inflammation affecting ventricular myocardium are strongly associated with AF and demonstrate significant correlation with fibrosis extent that cannot be explained by cardiovascular comorbidities otherwise.	28011843
Inflammation, Non-alcoholic Fatty Liver Disease, Obesity	Altered Intercellular Communication	Low-grade chronic inflammation emerges as a potent driver of insulin resistance and glucose dysregulation in obesity and associated non-alcoholic fatty liver disease (NAFLD).	28011892
Inflammation, Fatty degeneration	Altered Intercellular Communication	Hepatocyte-specific, but not adipose tissue-specific deletion of Ifnar1 worsened steatosis and inflammation induced by the MCD diet.	28011892
Inflammation, Organomegaly, Gaucher Disease	Altered Intercellular Communication	These factors contribute to defective deposition and clearance of apoptotic cells in phagolysosomes, which may have an impact on the inflammatory response and contribute to the organomegaly and inflammation seen in patients with Gaucher disease.	28011901
Inflammation, HIV	Altered Intercellular Communication	Cytomegalovirus Acquisition and Inflammation in Human Immunodeficiency Virus-Exposed Uninfected Zimbabwean Infants.	28011912
Inflammation, HIV	Altered Intercellular Communication	Cytomegalovirus (CMV) acquisition and inflammation were evaluated in 231 human immunodeficiency virus (HIV)-exposed uninfected (HEU) and 100 HIV-unexposed Zimbabwean infants aged 6 weeks.	28011912
Inflammation, Diabetes Mellitus, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Low-grade inflammation is involved in the development of diabetes and cardiovascular disease (CVD).	28012280
Inflammation	Altered Intercellular Communication	Generally, the available data suggest a neutral role of dairy product consumption on inflammation.	28012280
Pneumonitis, Pneumonia	Altered Intercellular Communication	Organizing pneumonia (OP) is a histopathological response pattern to lung inflammation.	28012487
Inflammation, Retinitis Pigmentosa, polychondritis	Altered Intercellular Communication	Relapsing polychondritis (RP) is characterized by recurrent systemic inflammation of the cartilages and is accompanied by central airway collapse.	28012498
Fibrosis Assessment, Gastrointestinal inflammation, Intestinal Diseases	Altered Intercellular Communication	Fecal calprotectin (FC) is used to asses the presence of intestinal inflammation also in patients with Cystic Fibrosis (CF) and recent studies showed a correlation between bowel and lung disease in these patients.	28012584
Inflammation, Tissue damage, Inflammatory disorder, Choline Dehydrogenase, Mitochondrial, Dental Plaque	Altered Intercellular Communication	It is now widely accepted that CHD is an inflammatory disease and that macrophages within plaque together with tissue damage contribute to this inflammation.	28012609
Inflammation, Primary malignant neoplasm, FAM126A gene	Altered Intercellular Communication	The gene expression of FNDC5/Irisin, associated to key regulators of DNL, inflammation and cancer progression was evaluated in liver tissue of 18 patients with HCC undergoing liver transplantation and of 18 deceased donors.	28012856
Endothelial dysfunction	Altered Intercellular Communication	Here, we suggest that acute DEP exposure produces intracellular reactive oxygen species (ROS) leading to induction of DEP internalization, endothelial dysfunction, and pro-inflammation in an in vitro human umbilical vein endothelial cells (HUVEC) model.	28013216
Inflammation, TMPRSS11D gene, Trypanosomiasis	Altered Intercellular Communication	Inhibition of this pathway ameliorates CNS inflammation in rodent models of the late (meningoencephalitic) stage of human African trypanosomiasis (HAT).	28013248
Inflammation, Atherosclerosis	Altered Intercellular Communication	Chronic low grade inflammation is a common background for atherosclerosis development; however, increased plaque inflammation may predispose by itself to PR.	28013285
Inflammation	Altered Intercellular Communication	In the last decade, studies performed by optical coherence tomography (OCT) have allowed to establish the severity of plaque inflammation by assessing macrophage infiltration (MOI).	28013285
Pain Distress Question, Inflammation	Altered Intercellular Communication	Opiorphin is a pentapeptide isolated from human saliva that suppresses pain from chemically induced inflammation and acute physical pain.	28013436
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Monocyte and monocyte to high-density lipoprotein ratio (MHR) recently emerged as markers of inflammation and have been reported to be novel prognostic indicators of cardiovascular diseases.	28017204
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Chronic inflammation plays a central role in the development and progression of diabetes, and in the pathogenesis of its complications.	28017281
Inflammation	Altered Intercellular Communication	The neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are indicators of subclinical inflammation.	28017281
Prediabetes syndrome, diabetic	Altered Intercellular Communication	Inflammation marker NLR significantly increases in prediabetic and diabetic patients.	28017281
Cessation of life, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation and elevated levels of fibroblast growth factor 23 are independent risk factors for death in chronic kidney disease.	28017325
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation is a consequence of chronic kidney disease (CKD) and is associated with adverse outcomes in many clinical settings.	28017325
Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation stimulates production of fibroblast growth factor 23 (FGF23), high levels of which are independently associated with mortality in CKD.	28017325
Cessation of life, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Few large-scale prospective studies have examined inflammation and mortality in patients with CKD, and none tested the interrelationships among inflammation, FGF23, and risk of death.	28017325
Traditional Serrated Adenoma, Inflammation, Dysplasia, Duodenal Cancer, Ulcer, Hyperplastic Polyp, Serrated Nodule	Altered Intercellular Communication	Serrated lesions were found in different mucosal lesions, with 14 lesions were detected in polyps (8 hyperplastic polyps and 6 serrated adenomas with low grade dysplasia), 3 detected in Menetrier gastropathy, 3 detected in an area of inflammation or ulcer, and 1 detected in the intramucosal carcinoma of the duodenum.	28018111
Inflammation, Impaired cognition, Dental Plaque	Altered Intercellular Communication	In summary, deficient daily oral hygiene, evidenced by greater bacterial dental plaque accumulation and gingival inflammation, is independently associated with cognitive impairment, even at its earliest stage.	28024093
Inflammation	Altered Intercellular Communication	Moreover, we compared inflammation in the EMB sampling area of the LVPW to the remaining myocardium of the LVPW and observed a significant increase of CD45+CD68 cells per mm2 in patients with LM.	28025077
Pain Distress Question, Breast Implant-Related Lesion	Altered Intercellular Communication	Two patients (one with inflammation-induced pain, one with implant-related pain) developed prolonged postoperative allodynia requiring pain-relief medication.	28025370
High Density Lipoproteins, Loss, Trauma, Nervous System	Altered Intercellular Communication	In HDLS cases, MRS revealed decreased NAA and Glu concentrations, which probably reflected neuronal damage and/or loss, and a subsequent reduction of neurotransmitters.	28025469
Granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	The histologic examination revealed granulomatous inflammation consistent with tuberculosis.	28025474
Craniosynostosis	Altered Intercellular Communication	The sino-nasal disease chronic rhinosinusitis (CRS) is primarily an inflammatory condition that manifests in several ways.	28025987
Encephalitis, Inflammation, LGI1 protein, human	Altered Intercellular Communication	Leucine-rich glioma-inactivated1 (LGI1) encephalitis is an antibody-associated inflammation of the limbic area.	28026046
Prostate carcinoma, Neoplasms	Altered Intercellular Communication	Further supporting a role of inflammation-induced immune-suppression in the development of early-onset prostate cancer, we observed significant up-regulation of CTLA4 and IDO1/TDO2 pathways in tumors of the young cohort.	28027300
Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Ang2 levels were significantly higher in the liver of CHC patients compared to controls and significantly correlated with inflammation and fibrosis.	28027429
Inflammation, Nodular lymphoid hyperplasia, Irritable Bowel Syndrome	Altered Intercellular Communication	Nodular lymphoid hyperplasia: A marker of low-grade inflammation in irritable bowel syndrome?	28028368
Abdominal bloating, Inflammation, Lactose Intolerance, Diarrhea, Abdominal Pain, Dermatitis, Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	NLH cases shared some distinctive clinical features among IBS patients: they were younger, more often female, and had a higher frequency of abdominal pain, bloating, diarrhoea, unspecific inflammation, self-reported lactose intolerance and metal contact dermatitis.	28028368
Inflammatory Bowel Diseases, Inflammation, Ichthyosis Bullosa of Siemens	Altered Intercellular Communication	About 1/3 of patients with IBS-type symptoms or suspected IBD presented diffuse colonic NLH, which could be a marker of low-grade inflammation in a conspicuous subset of IBS patients.	28028368
Inflammation, Thrombosis, Cerebrovascular accident, ASAH1 gene, Subarachnoid Hemorrhage, Aneurysmal	Altered Intercellular Communication	Inflammation and thrombosis are associated with the pathogenesis of aneurysmal subarachnoid hemorrhage (aSAH) and neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are emerging as novel inflammatory markers in stroke.	28028791
Thrombosis	Altered Intercellular Communication	This risk is apparent in patients with imminent GCA unexposed to oral glucocorticoids, suggesting a role for inflammation-associated thrombosis that is independent of glucocorticoid use.	28029234
Inflammation, Asthma, Sinusitis	Altered Intercellular Communication	In adults with asthma, CT imaging evidence of severe sinusitis indicates intense Th2-related inflammation, regardless of smoking status.	28029801
Inflammation, Perforation (observation)	Altered Intercellular Communication	A 24-year-old male with a left conchal inflammation and perforation visited our plastic surgery department after receiving augmentation rhinoplasty and tip plasty using a conchal cartilage graft.	28032171
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	These data indicate that genetic variation within the CR1 gene is associated with inflammation and the risk of incident coronary artery disease.	28033544
Late onset asthma, selenium, Inflammation	Altered Intercellular Communication	SE sensitization contributes to TH2 inflammation in nonatopic and/or late-onset asthma.	28034578
Inflammation, Failure (biologic function), Uveitis	Altered Intercellular Communication	Main outcome measures were failure of complete resolution of uveitis or recurrence of inflammation.	28035499
Inflammation, Fibrosis Assessment, Injury of liver	Altered Intercellular Communication	Importantly, neddylation inhibition, by using the pharmacological inhibitor, MLN4924, reduced liver injury, apoptosis, inflammation, and fibrosis by targeting different hepatic cell types.	28035772
Cessation of life, Inflammation, hepatic stellate cell activation	Altered Intercellular Communication	Under these circumstances, decreased hepatocyte cell death and inflammation after neddylation inhibition could partly account for reduction of hepatic stellate cell (HSC) activation.	28035772
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Recently, IL-34 was found to be associated with chronic inflammation, such as in rheumatoid arthritis (RA).	28036035
Kidney Failure, Chronic, Inflammation, Calcification of coronary artery, SLC25A20 gene, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	In end-stage renal disease (ESRD), coronary artery calcification (CAC) and inflammation contribute to cardiovascular disease (CVD).	28036114
Inflammation, SLC25A20 gene, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus	Altered Intercellular Communication	The association between CAC score and mortality remained significant after adjustment for age, gender, diabetes, CVD, use of statins, protein-energy wasting and inflammation.	28036114
Kidney Failure, Chronic, Inflammation, SLC25A20 gene	Altered Intercellular Communication	Elevated CAC score is a mortality risk factor in ESRD independent of inflammation.	28036114
Inflammation, Comorbidity	Altered Intercellular Communication	As the HIV-infected population ages, the role of cellular senescence and inflammation on co-morbid conditions and pharmacotherapy is increasingly of interest.	28036343
Inflammation	Altered Intercellular Communication	While inflammation is known to play a role in this population, it is not a major contributor to the p16INK4a association with decreased IM/EN exposures in these HIV-infected participants.	28036343
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Serum or plasma proteases have been associated with various diseases including cancer, inflammation, or reno-cardiovascular diseases.	28038565
HD Term Type	Altered Intercellular Communication	Malnutrition-Inflammation-Atherosclerosis (MIA) factors significantly and independently affect life prognosis of hemodialysis (HD) patients.	28038804
Cystitis	Altered Intercellular Communication	The urinary tract inflammation rate (21%) was higher than that reported anecdotally.	28038931
Inflammation, Lung	Altered Intercellular Communication	The role of IL-17B in regulating pulmonary immunity and inflammation is unknown.	28039016
Inflammation, Lung, Pneumonia	Altered Intercellular Communication	In conclusion, human pneumonia was associated with enhanced release of IL-17B, which might regulate pulmonary immunity and inflammation through the induction of IL-8 in bronchial epithelial cells.	28039016
Granulomatosis, Systemic Vasculitis	Altered Intercellular Communication	Environmental factor and inflammation-driven alteration of the total peripheral T-cell compartment in granulomatosis with polyangiitis.	28040323
Autoimmune Diseases, Inflammation, Tissue damage	Altered Intercellular Communication	Autoimmune diseases are initiated by a combination of predisposing genetic and environmental factors resulting in self-perpetuating chronic inflammation and tissue damage.	28040323
Communicable Diseases, Inflammation, Cytomegalovirus	Altered Intercellular Communication	Altogether, on a genetic and cellular basis, here we show that alterations of the peripheral T-cell compartment are driven by inflammation and various environmental factors including concomitant CMV and EBV infection.	28040323
Inflammation, Nodular lesions	Altered Intercellular Communication	This patient had two 2-cm diameter chronic nodular lesions over the right mandible with no local inflammation and no other clinical findings of systemic disease.	28040460
Acute GVH disease	Altered Intercellular Communication	In multivariate analysis, growth hormone (GH) deficiency (hazard ratio [HR], 8.6; 95% confidence interval [CI], 2.1 to 34.4; P = .002), history of cranial radiation (HR, 4.0; 95% CI, 1.7 to 9.6; P = .002), and grade II-IV acute graft-versus-host disease GVHD (HR, 4.2; 95% CI, 1.5 to 12.2; P = .008) were associated with the risk of developing a CVRF cluster.	28040534
Inflammation	Altered Intercellular Communication	The monocyte to high-density lipoprotein ratio has recently emerged as an indicator of inflammation and oxidative stress.	28040764
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Plasma TWEAK levels do not reflect disease activity or the grade of inflammation in patients with newly diagnosed inflammatory bowel disease.	28040992
Hidradenitis Suppurativa, Inflammation	Altered Intercellular Communication	Biologics seem to offer a promising nonsurgical approach in hidradenitis suppurativa (HS), especially in disease with highly pronounced inflammation.	28041632
Renal Insufficiency, Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	D-dimer and vWF were significantly and positively associated with NT-proBNP (a marker of neurohormonal activation and left ventricular wall stress) even after adjustment for age, lifestyle characteristics, renal dysfunction, atrial fibrillation (AF) and inflammation (C-reactive protein).	28043678
Disruption, Trauma, Nervous System	Altered Intercellular Communication	We hypothesise that vascular disruption and concomitant release of monomeric-C-reactive protein within the brain tissue could exacerbate ongoing neurological damage via stimulation of neuro-inflammation and from direct consequences of its action on both neuronal and vascular cells.	28044308
Inflammation, Negative Regulation of Cell Cycle	Altered Intercellular Communication	Cellular senescence is characterized by a permanent cell-cycle arrest and a pro-inflammatory secretory phenotype, and can be induced by a variety of stimuli, including ionizing radiation, oxidative stress, and inflammation.	28045034
Inflammation, Thymus Hyperplasia	Altered Intercellular Communication	MG pathophysiology includes a strong component of inflammation, and a large proportion of patients with early onset MG additionally present thymus hyperplasia.	28045063
Communicable Diseases, Inflammation	Altered Intercellular Communication	Inflammaging is defined as low-grade, chronic, systemic inflammation in aging, in the absence of overt infection.	28045067
Communicable Diseases, Inflammation	Altered Intercellular Communication	Inflammaging is defined as low-grade, chronic, systemic inflammation in aging, in the absence of overt infection.	28045067
Inflammation	Altered Intercellular Communication	It was concluded that antigenic burdens encountered in intestine throughout life create the condition of chronic stage of inflammation, which accumulates M2-like macrophages expressing TNF-a.	28045067
Granulomatosis, Orofacial, Granulomatous inflammation, Swelling	Altered Intercellular Communication	Orofacial granulomatosis (OFG) is a controversial entity mainly characterised by recurrent or permanent soft tissue swelling of sudden onset in the orofacial area with a histologic appearance of granulomatous inflammation.	28045322
Granulomatous inflammation	Altered Intercellular Communication	A biopsy of the lower labial mucosa revealed granulomatous inflammation consistent with OFG.	28045322
Inflammation	Altered Intercellular Communication	Colonoscopy showed inflammation without clear evidence of CD.	28045322
Granulomatous inflammation, Swelling	Altered Intercellular Communication	The differential diagnosis in cases of orofacial swellings with histological granulomatous inflammation includes a variety of local and systemic diseases, diagnosis and management of which require full investigation and cooperation by a team of healthcare providers.	28045322
Inflammation, Lymphoma	Altered Intercellular Communication	This rare case of lymphoma in a patient with a history of foreign body injection indicated that practitioners must be aware that long-standing chronic inflammation resulting from dermal filler injections can trigger lymphoma development.	28045813
Airway structure, ARCN1 gene	Altered Intercellular Communication	Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids.	28049170
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Long-term treatment with inhaled corticosteroids (ICS) might attenuate lung function decline and decrease airway inflammation in a subset of patients with chronic obstructive pulmonary disease (COPD), and discontinuing ICS treatment could result in further lung function decline.	28049170
Airway structure, ARCN1 gene	Altered Intercellular Communication	The sputum total cell counts increased significantly in GL2 (1.90, 95% CI 1.42-2.54), as did counts of macrophages (2.10, 95% CI 1.55-2.86), neutrophils (1.92, 95% CI 1.39-2.65) and lymphocytes (2.01, 95% CI 1.46-2.78).ICS discontinuation increases airway inflammation in patients with moderate-severe COPD, suggesting that the anti-inflammatory effects of ICS in COPD are not maintained after ICS discontinuation.	28049170
Inflammation	Altered Intercellular Communication	Those who concurrently had PEW, inflammation, and CVD were a small proportion (0.4%).	28049236
Inflammation, Cholangiocarcinoma, Angiomyolipoma, Ovarian Cystadenocarcinoma, Bile duct adenoma, Cortical adenoma of kidney, Hepatoblastoma, Dysplastic nodule, Hemangioma, Malignant Neoplasms, Stage IV Nasopharyngeal Carcinoma, Lymphoepithelial carcinoma, Non-Neoplastic Disorder	Altered Intercellular Communication	Of the 18 patients, 7 patients (0.8%) were diagnosed with benign conditions (one each of hemangioma, inflammation, cortical adenoma, dysplastic nodule, angiomyolipoma, bile duct adenoma, and non-neoplastic liver parenchyme) and 11 patients (1.3%) were diagnosed with malignancies (cholangiocarcinoma [n = 6], hepatoblastoma [n = 2], and one each of lymphoepithelioma-like carcinoma, ovarian cystadenocarcinoma, and nasopharynx carcinoma metastasis).	28049244
Inflammation, Malnutrition, Diabetes Mellitus	Altered Intercellular Communication	This simple and readily available tool allows estimation of patient survival independently of other well-known key parameters such as age, gender, the presence of diabetes and markers of malnutrition and inflammation.	28049587
Inflammation, Neuropathology	Altered Intercellular Communication	Inflammation is targeted as responsible for the development of many neurologic pathologies.	28050702
Inflammation, Carcinoid Tumor	Altered Intercellular Communication	A better understanding of how inflammation induces cytological changes leading to development of a carcinoid from a cellular and molecular perspective could provide potential therapeutic strategies for preventing these lesions.	28050998
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Lacrimal gland-derived IL-22 regulates IL-17-mediated ocular mucosal inflammation.	28051088
Inflammation, Ulcer	Altered Intercellular Communication	Barium esophagography, gastroesophageal endoscopy, and biopsy suggested esophageal-related chronic inflammation and ulcer, which probably caused the repeated esophagobronchial fistulas observed.	28051197
Inflammation, Chronic infectious disease, Atherosclerosis	Altered Intercellular Communication	To test if circulating levels of markers of inflammation, endothelial function, and chronic infections, as well as association between these markers and carotid intima media thickness (CIMT), depend on the stage of atherosclerosis expressed as a history of a major vascular event.	28051279
Inflammation, Carcinogenesis	Altered Intercellular Communication	Genetic variation in PPARGC1A may affect the role of diet-associated inflammation in colorectal carcinogenesis.	28051997
Inflammation, Carcinogenesis	Altered Intercellular Communication	The role of inflammation in colorectal carcinogenesis may differ according to individuals' genetic variations.	28051997
Inflammatory Bowel Diseases, Inflammation, Carcinogenesis	Altered Intercellular Communication	Inflammation is the driving force in inflammatory bowel disease (IBD) and its link to oxidative stress and carcinogenesis has long been accepted.	28052094
Inflammation	Altered Intercellular Communication	They might reduce Qmax rate and lead to reduction of the f/t PSA ratio and produce more severe inflammation causing increased seminal concentration of IL-1b and IL-8.	28052296
indurated, Scleroderma , Abnormal color	Altered Intercellular Communication	Morphoea (localized scleroderma) is a cutaneous inflammatory condition characterized by the development of indurated and discoloured plaques.	28052367
Liver carcinoma, Hepatitis, Chronic, Liver Cirrhosis, FAM126A gene	Altered Intercellular Communication	Most patients with a hepatocellular carcinoma (HCC) have an underlying chronic liver inflammation, which causes a continuous damage leading to liver cirrhosis and eventually HCC.	28052383
Inflammation, Neoplasms	Altered Intercellular Communication	CD8+ T cells that express retinoic acid-related orphan receptor (ROR)gt (TC17 cells) have been shown to promote procarcinogenic inflammation and contribute to a tolerogenic microenvironment in tumors.	28053236
Squamous cell carcinoma	Altered Intercellular Communication	Immunosuppression Induced by Chronic Inflammation and the Progression to Oral Squamous Cell Carcinoma.	28053372
Inflammation, SERPINB3 wt Allele	Altered Intercellular Communication	The results suggested that the immunosuppression induced by chronic inflammation promotes tumorigenesis in OSCC, rather than initiating it.	28053372
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The aim of this study was to describe the histological features of erosive hand osteoarthritis (EHOA), which is considered an aggressive subset of hand osteoarthritis (OA) characterized by severe local inflammation and degeneration of the distal and proximal interphalangeal joints.	28054155
Liver carcinoma	Altered Intercellular Communication	Coenzyme Q10 and Oxidative Stress: Inflammation Status in Hepatocellular Carcinoma Patients after Surgery.	28054958
Inflammation, Hepatocarcinogenesis, FAM126A gene	Altered Intercellular Communication	The level of coenzyme Q10 was significantly positively correlated with antioxidant capacity (vitamin E and glutathione peroxidase activity) and negatively correlated with inflammation markers after surgery; (4) Conclusion: Hepatocarcinogenesis is associated with oxidative stress, and coenzyme Q10 may be considered an antioxidant therapy for patients with HCC, particularly those with higher inflammation after surgery.	28054958
Inflammation, Endophthalmitis, CTCAE, Panophthalmitis	Altered Intercellular Communication	Panophthalmitis is the most extensive ocular involvement in endophthalmitis with inflammation in periocular tissues.	28056067
Inflammation, Rupture, Scleral abscess, Perforation (observation), Corneal Opacity	Altered Intercellular Communication	Severe inflammation of the anterior and posterior segments is frequently accompanied by corneal opacity, scleral abscess, and perforation or rupture.	28056067
Autoimmune Chronic Hepatitis, Hepatitis, Liver Stiffness	Altered Intercellular Communication	Influence of Liver Inflammation on Liver Stiffness Measurement in Patients with Autoimmune Hepatitis Evaluation by Combinational Elastography.	28056459
Fibrosis Assessment, Hepatitis, Insemination, Artificial, Homologous	Altered Intercellular Communication	Combinational elastography was useful in evaluating not only the degree of liver fibrosis, but also the degree of liver inflammation in AIH.	28056459
Inflammation, Fibrosis Assessment, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Idiopathic pulmonary fibrosis (IPF) is characterized by the complex interaction of cells involved in chronic inflammation and fibrosis.	28057004
Renal Insufficiency, Inflammation, Nephrotoxic, Bacterial Endocarditis	Altered Intercellular Communication	Patients with infective endocarditis (IE) have an elevated risk of renal dysfunction because of extensive systemic inflammation and use of nephrotoxic antibiotics.	28057030
Inflammation, Vitamin B 12 Deficiency	Altered Intercellular Communication	Cobalamin deficiency was caused by asymptomatic chronic atrophic inflammation of the stomach with a lack of intrinsic factor producing gland cells.	28057043
Inflammation, Aneurysm	Altered Intercellular Communication	Hub protein of IKBKG in protein-protein interaction network was probably involved in the inflammation process in aneurysms.	28057588
Inflammation, Liver diseases	Altered Intercellular Communication	Oxidative stress and altered levels of different trace elements in serum have been documented for different diseases including inflammation and many liver diseases.	28058664
Inflammation, Chronic disease, Cardiovascular Diseases	Altered Intercellular Communication	Oxidative stress and inflammation are central to the development of a number of chronic diseases including cardiovascular disease and previous research suggests that blueberry consumption may attenuate these processes.	28059417
Temporomandibular Joint Disorders, Inflammation, Psychiatric, Chronic neck pain	Altered Intercellular Communication	Analysis of comorbidities revealed temporomandibular joint disorder, chronic cervical pain, depression/anxiety, and psychiatric medication use to be negatively associated with objective inflammation on CT or endoscopy.	28059446
Inflammation, Sinusitis, Headache Disorders, Primary	Altered Intercellular Communication	Given the high prevalence of sinusitis, improved clinical diagnostic criteria may assist primary care providers in more accurately predicting the presence of inflammation, thereby reducing inappropriate antibiotic use or delayed referral for evaluation of primary headache syndromes.	28059446
Pain Distress Question, Inflammation	Altered Intercellular Communication	None of the patients complained of worsening vision or pain after the intravitreal injections and no intraocular inflammation was seen.	28060148
Inflammation, Sternoclavicular joint structure, Hyperostosis	Altered Intercellular Communication	Further evaluation revealed hyperostosis of the sacroiliac joint and inflammation of the bilateral sternoclavicular joints and right sternocostal joint.	28060551
Inflammation, Necrosis	Altered Intercellular Communication	Abdominal computed tomography (10 days after admission) demonstrated a thickened pancreas in connection with inflammation and two small hypodense foci in the anterior part of the pancreas body, translating small foci of necrosis.	28060696
Chronic sclerosing sialadenitis	Altered Intercellular Communication	Chronic sclerosing sialadenitis is a benign inflammatory condition that most commonly affects the submandibular gland in elderly individuals.	28060780
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	Tumor plasma contained a substantial tumor lysis signature, most prominent in Em-myc plasma, whereas Em-TCL1 plasma contained signatures of immune-response, inflammation and microenvironment interactions, with putative biomarkers in early-stage cancer.	28062796
Inflammation, Asthma	Altered Intercellular Communication	Inhaled corticosteroid dose response in asthma: Should we measure inflammation?	28065396
Airway structure	Altered Intercellular Communication	ICSs may not be increased on this basis despite residual airway inflammation.	28065396
Inflammation, Asthma	Altered Intercellular Communication	To compare the dose-response relationships of ICSs on measures of pulmonary function, symptoms, and inflammation in patients with persistent asthma.	28065396
Inflammation, AHR wt Allele	Altered Intercellular Communication	ICS dose response may extend beyond low dose for inflammation and AHR but not symptoms or spirometry.	28065396
Inflammation, Acute myocardial infarction, Reperfusion Injury	Altered Intercellular Communication	Inflammation is involved during acute myocardial infarction, and could be an interesting target to prevent ischaemia-reperfusion injuries.	28065445
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	To evaluate the impact of colchicine on inflammation in patients admitted for ST-segment elevation myocardial infarction (STEMI).	28065445
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Inflammation is the most important link between obesity and type 2 diabetes (T2D).	28067023
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Traditional Chinese herbal medicine (TCM) has been used in Chinese society for more than 5,000 years to treat diseases from inflammation to cancer.	28067535
NUMBL gene, Central neuroblastoma, Inflammation	Altered Intercellular Communication	The aim of this study was to analyze the prevalence of frailty and physical health limitations among long-term survivors of high-risk neuroblastoma (HR NBL) and to investigate whether frail health is associated with variables of cardiovascular function, markers of inflammation and telomere length.	28067869
Autoimmune Diseases, Inflammation, Prohepcidin, Refractory anemias	Altered Intercellular Communication	Prohepcidin positively correlated with the parameters of inflammation (CRP, ESR) and with the parameters for evaluation of autoimmune disorders (DAS 28 and RF) in the RA group.	28068286
Inflammation, Prohepcidin	Altered Intercellular Communication	The increase of both parameters provides information for tissue iron deficiency (assessed by the level of sTfR), caused by the inflammation when prohepcidin is expressed.	28068286
Hidradenitis Suppurativa, Inflammation, Chronic disease, Specimen Source Codes - Abscess	Altered Intercellular Communication	Hidradenitis suppurativa (HS) is a debilitating chronic disease that leads to inflammation and abscess formation in the involved skin, along with a malodorous discharge.	28068657
Symptoms, Inflammation, Exacerbation	Altered Intercellular Communication	This often leads to over-reliance on short-acting b2-agonist (SABA) reliever medication and under-treatment of the underlying inflammation, with poor control of asthma symptoms and increased risk of exacerbations.	28069068
Bacteremia, Inflammation	Altered Intercellular Communication	Transient bacteraemia, following urinary catheterisation, with seeding of existing sites of inflammation is the proposed explanation.	28069785
Inflammation, Phenylketonurias	Altered Intercellular Communication	Phenylketonuria is not a risk factor for changes of inflammation status as assessed by interleukin 6 and interleukin 8 concentrations.	28071012
Inflammation, Phenylketonurias	Altered Intercellular Communication	High oxidative stress and a reduced potential for free radical scavenging in phenylketonuria (PKU) patients, a phenomenon confirmed in a few studies, may lead to systemic chronic inflammation.	28071012
Inflammation, Phenylketonurias	Altered Intercellular Communication	Phenylketonuria is not a risk factor for changes of inflammation status as assessed by IL-6 and IL-8 concentrations.	28071012
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Chemerin levels are significantly linked to inflammation and metabolic syndrome.	28071854
Inflammation, Adenocarcinoma Of Esophagus	Altered Intercellular Communication	Preoperative markers of systemic inflammation predict poor outcome in patients undergoing curative treatment for locally advanced oesophageal and gastro-oesophageal adenocarcinoma.	28072456
Inflammation	Altered Intercellular Communication	Inflammation is a key factor contributing to alterations in aerobic capacity, and interleukin (IL)-1 cytokines are implicated in this process.	28072632
Leydig Cell Tumor, Inflammation, Neoplasms, Fibrosis Assessment, Sertoli Cell Tumor, Angiofibroma, Malignant Neoplasms, Tubular atrophy, Seminoma, Adenomatoid Tumor	Altered Intercellular Communication	Definitive pathological results were: malignant tumor in 6 cases (seminoma), benign tumor in 10 cases (5 Leydig tumors, 2 Sertoli tumors, 1 epidermoid cyst, 1 adenomatoid tumor, 1 angiofibroma), benign disease in 11 (8 inflammation with haemorragic infiltration, 2 tubular atrophy, 1 fibrosis), and normal parenchyma in 1 case.	28073203
Inflammation, Primary malignant neoplasm, Patient Satisfaction with Cancer Care Questionnaire	Altered Intercellular Communication	However, altered gene expression in PSCC affects canonical pathways and cellular and biological processes, such as inflammation and DNA damage response, which are highly consistent with hallmarks of cancer.	28073359
Airway structure, Progranulins, Asthma	Altered Intercellular Communication	Serum progranulin as an indicator of neutrophilic airway inflammation and asthma severity.	28073702
Inflammation, Progranulins	Altered Intercellular Communication	Progranulin, a protein secreted from the airway epithelium, is known to attenuate the downstream cascade of neutrophilic inflammation in particular.	28073702
Refractory anemias, Rheumatoid Arthritis, Electrocardiogram: myocardial infarction (finding), Inflammation	Altered Intercellular Communication	Patients with rheumatoid arthritis (RA) are at increased risk of myocardial infarction (MI) compared with subjects without RA, with the increased risk driven potentially by inflammation.	28073800
Inflammation, Gastrointestinal Diseases	Altered Intercellular Communication	More recently, it has been shown that H. pylori cytotoxin CagA expression induces cellular senescence of human gastric nonpolarized epithelial cells that may lead to gastrointestinal disorders and systemic inflammation.	28074309
Inflammation	Altered Intercellular Communication	The manifestations of the present case suggest that a systemic inflammation might occur in the unicentric form of the disease possibly due to cytokine hypersecretion.	28074445
Inflammation, Angiolymphoid hyperplasia	Altered Intercellular Communication	Unicentric disease is a surgical condition and warrants a follow-up based on the systemic inflammation that might occur.	28074445
Helicobacter cinaedi, atherosclerotic	Altered Intercellular Communication	The Helicobacter cinaedi antigen CAIP participates in atherosclerotic inflammation by promoting the differentiation of macrophages in foam cells.	28074932
Coinfection, Inflammation, Atherosclerosis	Altered Intercellular Communication	Recent studies have shown that certain specific microbial infections participate in atherosclerosis by inducing inflammation and immune reactions, but how the pathogens implicated in this pathology trigger the host responses remains unknown.	28074932
Inflammation, atherosclerotic, Atherosclerosis	Altered Intercellular Communication	CAIP appears to be implicated in this pathology because atheromatous plaques isolated from atherosclerotic patients are enriched in CAIP-specific T cells (10%) which, in turn, we show to drive a Th1 inflammation, an immunopathological response typically associated to atherosclerosis.	28074932
Communicable Diseases, Atherosclerosis	Altered Intercellular Communication	This study identifies CAIP as a relevant factor in atherosclerosis inflammation linked to Hc infection and suggests that preventing and eradicating Hc infection could reduce the incidence of atherosclerosis.	28074932
Inflammation, Fibrosis Assessment, Liver Stiffness	Altered Intercellular Communication	Coffee consumption decreases liver stiffness, which may indicate less fibrosis and inflammation, independent of disease state.	28075394
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Inflammation, cardiometabolic markers, and functional changes in men with prostate cancer.	28075422
Communicable Diseases, Inflammation	Altered Intercellular Communication	We studied their association with inflammation (C-reactive protein), infection (procalcitonin) and clinical outcome.	28076309
Sepsis, Communicable Diseases, Inflammation	Altered Intercellular Communication	IDO and kynurenine showed a strong positive correlation with markers of infection (procalcitonin) and inflammation (C-reactive protein) as well as sepsis and CAP severity scores.	28076309
Neoplasms	Altered Intercellular Communication	The predictive performance of AGR was compared with other inflammation-based scores and serological tumor markers in terms of concordance index (C-index).	28076328
Neoplasms	Altered Intercellular Communication	The C-index of AGR was superior to other inflammation-based scores and serological tumor markers in OS and RFS prediction.	28076328
Metastatic urothelial carcinoma	Altered Intercellular Communication	Novel Inflammation-Based Prognostic Score for Predicting Survival in Patients with Metastatic Urothelial Carcinoma.	28076369
Nail-Patella Syndrome, Carcinoma, Transitional Cell, Ulcerative Colitis	Altered Intercellular Communication	We developed a novel inflammation-based model (NPS), which consisted of a neutrophil to lymphocyte ratio (NLR) and platelet count (PC), for assessing the prognostic role in patients with metastatic urothelial carcinoma (UC).	28076369
Communicable Diseases, Arthritis, Inflammation	Altered Intercellular Communication	During active infection, miRNA expression in SF reflected an immune response associated with bacterial killing, while in postinfectious LA, miRNA expression in SF and synovial tissue reflected chronic inflammation, synovial proliferation, and breakdown of wound repair processes, showing that the nature of the arthritis was altered after spirochetal killing.	28076897
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	With such combined changes in lipids, lipid sub-fractions, and inflammation, which are considered among the most effective means of reducing coronary heart disease (CHD), this PMILLS represents a new addition to safe and effective lipid-modifying strategies.	28078862
Inflammation, AATF wt Allele, Dry Eye Syndromes	Altered Intercellular Communication	Lifitegrast is a lymphocyte function-associated antigen-1 antagonist developed to reduce inflammation in dry eye disease (DED).	28079022
Inflammation	Altered Intercellular Communication	TRIM22 is constitutively expressed at high levels in monocytes and plays important roles in the antiviral response and inflammation.	28079123
Inflammation, Pleural effusion disorder	Altered Intercellular Communication	Exudative pleural effusions may arise secondary to inflammation of intra-abdominal structures.	28079399
Inflammation, Hyperplasia, Internal, Cyst	Altered Intercellular Communication	CBA cysts typically lacked epithelium and inflammation; cyst walls had an inner, dense cicatricial layer associated with myofibroblastic (MF) hyperplasia that often delaminated producing a grossly visible inner cyst wall.	28079575
Inflammation, Observation Method - Coagulation, Hypoxia, Septic Shock	Altered Intercellular Communication	In patients with septic shock, alterations in inflammation, coagulation, oxidative stress, and tissue hypoxia are common and associated with adverse outcomes but are not influenced by protocol-based resuscitation compared with usual care.	28079606
Gastric mucosa	Altered Intercellular Communication	To investigate the value of quantitative analysis in dual energy spectral computed tomography (DESCT) for differentiating malignant gastric mucosal lesions from benign gastric mucosal lesions (including gastric inflammation [GI] and normal gastric mucosa [NGM]).	28079827
Inflammation	Altered Intercellular Communication	In BD patients, choroidal thickness decreased over time, which was associated with length of active inflammation.	28080153
Intraocular inflammation	Altered Intercellular Communication	It suggests intraocular inflammation in BD affects the choroid as well as the retina.	28080153
Inflammation, Hepatitis	Altered Intercellular Communication	A liver biopsy demonstrated portal inflammation and hepatitis with apoptotic hepatocytes.	28081586
Autoimmune Diseases, Lichen Sclerosus et Atrophicus, Infection, Traumatic injury	Altered Intercellular Communication	Several factors such as genetic susceptibility, autoimmunity, hormones, infections, local trauma, urine, and occlusion have been speculated to play a role in the pathogenesis of lichen sclerosus.	28081682
Abnormal renal function, Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Kidney dysfunction, systemic inflammation and mental well-being in elderly post-myocardial infarction patients.	28081723
Abnormal renal function, Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	The aim was to investigate whether mild kidney dysfunction and low-grade inflammation in post-myocardial infarction patients are independently associated with markers of mental well-being (i.e.	28081723
Inflammation, Electrocardiogram: myocardial infarction (finding), Bipolar Disorder, Renal function, Apathy	Altered Intercellular Communication	In post-myocardial infarction patients, impaired kidney function and systemic inflammation showed a stronger association with apathy than with depressive symptoms and dispositional optimism.	28081723
Pneumonitis	Altered Intercellular Communication	Previously, we described that protein arginine methyltransferase 1 (PRMT1) participates in airway remodeling in pulmonary inflammation in E3 rats.	28081849
Inflammation, Myocardial, CEL gene	Altered Intercellular Communication	A greater decline of circulating FAP concentrations in the first 5days after STEMI is associated with increased myocardial damage and inflammation.	28082091
Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Right ventricular (RV) morphology has been associated with drivers of atrial fibrillation (AF) risk, including left ventricular and pulmonary pathology, systemic inflammation, and neurohormonal activation.	28082528
Inflammation, Vitreous humor, Diabetic Retinopathy	Altered Intercellular Communication	Inflammation and N-formyl peptide receptors mediate the angiogenic activity of human vitreous humour in proliferative diabetic retinopathy.	28083635
Inflammation, PDR gene, Diabetic Retinopathy, Diabetes Mellitus	Altered Intercellular Communication	Angiogenesis and inflammation characterise proliferative diabetic retinopathy (PDR), a major complication of diabetes mellitus.	28083635
Inflammation, Pathologic Neovascularization	Altered Intercellular Communication	However, the impact of inflammation on the pathogenesis of PDR neovascularisation has not been elucidated.	28083635
Tinea profunda (disorder), Granulomatous inflammation, Arthrodermataceae	Altered Intercellular Communication	Majocchi's granuloma is an intracutaneous or subcutaneous granulomatous inflammation caused by invasion of dermatophytic fungus, especially Trichophyton rubrum.	28083794
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Shorter telomere length and obstructive sleep apnea are associated with increased oxidative stress and chronic inflammation, which are both considered leading causes of age-related diseases.	28083855
Hematoma, Swelling	Altered Intercellular Communication	Noninfectious prevertebral soft-tissue inflammation and hematoma eliciting swelling after anterior cervical discectomy and fusion.	28084931
Communicable Diseases, Inflammation, Esophageal Perforation	Altered Intercellular Communication	When it coincides with prevertebral space enlargement and inflammation, surgical site infection and pharyngoesophageal perforation must be considered.	28084931
Deglutition Disorders, Spondylitis	Altered Intercellular Communication	The association between dysphagia and prevertebral inflammation has not been reported.	28084931
Deglutition Disorders, Spondylitis	Altered Intercellular Communication	The authors investigated factors eliciting severe dysphagia and its relationship with prevertebral inflammation in patients who had undergone ACDF.	28084931
Inflammation, Hematoma, teratologic	Altered Intercellular Communication	In other cases these anomalies are elicited by hematoma not associated with inflammation.	28084931
Metabolic Diseases, Keratoconus	Altered Intercellular Communication	Therefore, metabolic disorder and hormonal balance may both have an impact on keratoconus development.	28085502
Inflammation, Biliary calculi	Altered Intercellular Communication	Acute acalculous cholecystitis (AAC) is an inflammation of the gallbladder without the presence of gallstones.	28085529
Neurodegenerative Disorders, Inflammation, Brain Injuries	Altered Intercellular Communication	Increased expression of translocator protein (TSPO) has been observed after brain injury and inflammation in neurodegenerative diseases.	28086916
Inflammation, Rheumatoid Arthritis, Physical disability, Synovitis	Altered Intercellular Communication	The relationship between synovitis quantified by an ultrasound 7-joint inflammation score and physical disability in rheumatoid arthritis - a cohort study.	28086960
Inflammation	Altered Intercellular Communication	It is unknown, whether the extent of synovial inflammation quantified by musculoskeletal ultrasound (US) can predict current or future capacity for physical functioning.	28086960
Inflammation, Hemorrhage, Electrocardiogram: myocardial infarction (finding), Coronary Arteriosclerosis, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Lymphocytic myocarditis occurs with myocardial infarction and coincides with increased inflammation, hemorrhage and instability in coronary artery atherosclerotic plaques.	28087177
Inflammation, Dental Plaque, Coronary Artery Vasospasm, atherosclerotic	Altered Intercellular Communication	Moreover, LM was associated with remodeling and inflammation of atherosclerotic plaques indicative of plaque destabilization pointing to coronary spasm, suggesting that preexistent LM, or its causes, may facilitate the development of MI.	28087177
Inflammation, Vesicoureteral Reflux 1, Hydronephrosis, Renal scarring	Altered Intercellular Communication	The following clinical variables were compared: age at diagnosis of primary VUR (months), sex, VUR grade, hydronephrosis grade, presence of renal scarring, surgical treatment, and degree of inflammation during fUTI.	28087230
Autoimmune Diseases, Acute and chronic inflammation	Altered Intercellular Communication	Populations of CD4+CD28null T cells, with apparently contradictory physiological roles, have recently been reported, along with the co-expression of the NK activating receptor NKG2D, in autoimmune diseases and chronic viral inflammation.	28087292
septic	Altered Intercellular Communication	Thioredoxin (TRX), an endogenous anti-oxidant protein induced in inflammatory conditions, has been shown to increase in plasma and to be associated with outcome in septic patients.	28087409
Celiac Disease, Gastrointestinal inflammation	Altered Intercellular Communication	While the pathophysiological link between the oral and gut microbiomes in CD needs further exploration, the presented data suggest that oral microbe-derived enzyme activities are elevated in subjects with CD, which may impact gluten processing and the presentation of immunogenic gluten epitopes to the immune system in the small intestine.IMPORTANCE Ingested gluten proteins are the triggers of intestinal inflammation in celiac disease (CD).	28087531
Inflammation, Impaired cognition, "Alzheimers Disease	Altered Intercellular Communication	Iso-a-acids, Bitter Components of Beer, Prevent Inflammation and Cognitive Decline Induced in a Mouse Model of Alzheimer's Disease.	28087694
Inflammation	Altered Intercellular Communication	Here we found that iso-a-acids, hop-derived bitter compounds in beer, enhance microglial phagocytosis and suppress inflammation via activation of the peroxisome proliferator-activated receptor g. In normal mice, oral administration of iso-a-acids led to a significant increase both in CD11b and CD206 double-positive anti-inflammatory type microglia (p < 0.05) and in microglial phagocytosis in the brain.	28087694
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	The present study is the first to report that amyloid b deposition and inflammation are suppressed in a mouse model of Alzheimer's disease by a single component, iso-a-acids, via the regulation of microglial activation.	28087694
Granuloma, Inflammation, Crohn Disease	Altered Intercellular Communication	Association of granulomas in mesenteric lymph nodes in Crohn's disease with younger age and transmural inflammation.	28087973
Granuloma, Inflammation, Abscess, Fibrosis Assessment, Hypertrophy, Intestines, Small	Altered Intercellular Communication	The presence of MLN granuloma was associated with mural granuloma, transmural inflammation, mural abscess, hypertrophy of the muscularis propria, fibrosis of the muscularis propria, and serosal fibrosis in the small bowel.	28087973
Granuloma, Inflammation	Altered Intercellular Communication	The multivariable analysis confirms that MLN granuloma was associated with age and transmural inflammation.	28087973
Granuloma, Inflammation	Altered Intercellular Communication	In CD patients who underwent the index ICR, the presence of MLN granuloma was associated with younger age and transmural inflammation.	28087973
Granuloma, Inflammation	Altered Intercellular Communication	Our current results suggest that the detection of MLN granulomas may be enhanced in patients at higher risk, that is, younger patients or those with transmural inflammation on imaging or histopathology.	28087973
Inflammation	Altered Intercellular Communication	However, the effect of SCE on inflammation in animals is still obscure.	28088324
Colitis	Altered Intercellular Communication	Mice in DSS and DSS+SCE groups were also given a 4% DSS solution from 7-week to 8-week-old via drinking water to induce colonic inflammation.	28088324
Damage, physiopathological, Colitis	Altered Intercellular Communication	The results showed that dietary SCE alleviated DSS induced growth suppression, splenic damage, colonic histological changes, colonic inflammation, oxidative stress, and colonic dysfunction of tight junctions.	28088324
Inflammation	Altered Intercellular Communication	In conclusion, SCE conferred a protective role in the DSS-induced inflammation and the mechanism might be associated with the activated signals of the nuclear factor kappa B p65 and Nrf2.	28088324
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Amygdalar activity was associated with increased bone-marrow activity (r=047; p<00001), arterial inflammation (r=049; p<00001), and risk of cardiovascular disease events (standardised hazard ratio 159, 95% CI 127-198; p<00001), a finding that remained significant after multivariate adjustments.	28088338
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The association between amygdalar activity and cardiovascular disease events seemed to be mediated by increased bone-marrow activity and arterial inflammation in series.	28088338
Arteritis	Altered Intercellular Communication	In the separate cross-sectional study of patients who underwent psychometric analysis (n=13), amygdalar activity was significantly associated with arterial inflammation (r=070; p=00083).	28088338
Inflammation	Altered Intercellular Communication	Perceived stress was associated with amygdalar activity (r=056; p=00485), arterial inflammation (r=059; p=00345), and C-reactive protein (r=083; p=00210).	28088338
Inflammation, Traumatic injury	Altered Intercellular Communication	Increased understanding of factors associated with inflammation after trauma and PRBC transfusion is needed.	28088436
Chronic prostatitis, prostatitis	Altered Intercellular Communication	Chronic Prostate Inflammation Predicts Symptom Progression in Patients with Chronic Prostatitis/Chronic Pelvic Pain.	28089730
prostatitis	Altered Intercellular Communication	We examined the 4-year longitudinal association between histological prostate inflammation and chronic prostatitis/chronic pelvic pain syndrome.	28089730
Inflammation, Pain Distress Question	Altered Intercellular Communication	At multiple time points during 4 years univariable and multivariable analyses were performed between acute and chronic inflammation detected on baseline biopsies and the incidence of chronic pelvic pain syndrome-like symptoms, defined as a positive response to CPSI (Chronic Prostatitis Symptom Index) question 1a-perineal pain and/or question 2b-ejaculatory pain and a total pain subscore of at least 4, and progression of chronic prostatitis/chronic pelvic pain syndrome, defined as a 4-point or greater increase from baseline in total CPSI score, in patients with a baseline categorization of chronic prostatitis/chronic pelvic pain syndrome.	28089730
Inflammation	Altered Intercellular Communication	Of the 4,109 men in the study acute and chronic inflammation was detected in 641 (15.6%) and 3,216 (78.3%), respectively.	28089730
Inflammation	Altered Intercellular Communication	Acute and chronic inflammation was not associated with the incidence of the symptoms (p >0.1).	28089730
Inflammation	Altered Intercellular Communication	Chronic but not acute inflammation was significantly associated with shorter time to progression on univariable and multivariable analyses (p = 0.029 and 0.018, respectively).	28089730
Inflammation	Altered Intercellular Communication	Inflammation is not associated with an increased risk of chronic prostatitis/chronic pelvic pain syndrome.	28089730
Inflammation	Altered Intercellular Communication	However, chronic inflammation predicts the risk of symptomatic progression in men in whom chronic prostatitis/chronic pelvic pain syndrome symptoms have been identified.	28089730
Inflammation, Primary malignant neoplasm, Carcinogenesis	Altered Intercellular Communication	Network analysis of known and putative mRNA targets of these miRs was enriched with cancer and inflammation pathways, consistent with known roles of stroma and of vitamin D in carcinogenesis.	28089917
Myocarditis, CTCAE 5.0, Myocarditis	Altered Intercellular Communication	Eosinophilic myocarditis is a rare form of myocardial inflammation that is characterized by the infiltration of eosinophilic cells into the myocardium.	28090045
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Impact of celecoxib on inflammation during cancer surgery: a randomized clinical trial.	28092065
Inflammation, Primary malignant neoplasm, Neoplasm Metastasis	Altered Intercellular Communication	During cancer surgery, prostaglandin-mediated inflammation may promote and activate micrometastatic disease with a consequent increase in long-term cancer recurrence.	28092065
Inflammation, Obesity	Altered Intercellular Communication	High-sensitivity C-reactive protein is increased and negatively associated with anti-oxidation in pre-pubertal obese boys, suggesting that childhood obesity is associated with aseptic inflammation and oxidative stress.	28092067
Inflammation	Altered Intercellular Communication	Low-grade, chronic inflammation has been associated with many diseases of aging, but the mechanisms responsible for producing this inflammation remain unclear.	28092664
Communicable Diseases, Inflammation	Altered Intercellular Communication	Inflammasomes can drive chronic inflammation in the context of an infectious disease or cellular stress, and they trigger the maturation of interleukin-1b (IL-1b).	28092664
Inflammation	Altered Intercellular Communication	Thus, targeting inflammasome components may ameliorate chronic inflammation and various other age-associated conditions.	28092664
Inflammation, Disease	Altered Intercellular Communication	Whilst C-reactive protein (CRP) is an established serum marker of inflammation, its use in gastroenterology has been limited by its poor sensitivity and specificity for GI disease.	28093196
Gastrointestinal inflammation	Altered Intercellular Communication	Faecal calprotectin (FC) has been adopted into mainstream GI practice as a sensitive but non-specific marker of intestinal inflammation.	28093196
Gastrointestinal inflammation	Altered Intercellular Communication	Therefore, as a serum biomarker for intestinal inflammation, SC is unlikely to be of clinical utility and the search for an appropriate serum GI biomarker continues.	28093196
Unresectable, Weight decreased, Inflammation	Altered Intercellular Communication	Eligible patients for the double-blind phase of this ongoing, placebo-controlled, randomised, phase 3 trial, had metastatic or unresectable disease, Eastern Cooperative Oncology Group performance status score 1 or 2, systemic inflammation, weight loss, and other disease-related morbidities associated with poor prognosis, and were refractory to oxaliplatin and irinotecan.	28094194
methyldopa, Inflammation	Altered Intercellular Communication	There is evidence that nutrition, inflammation and genetic risk factors play an important role in the development of AMD.	28094305
Inflammation, Metabolic Diseases	Altered Intercellular Communication	Recent studies suggest that the composition of the intestinal microbiome is associated with metabolic diseases through modulation of inflammation and host metabolism.	28094305
Inflammation, musculoskeletal regeneration	Altered Intercellular Communication	Overall this work demonstrates a novel method for modulating cell response to inflammatory signaling that has applications in engineering cells delivered to inflammatory environments, and as a direct gene therapy to protect endogenous cells exposed to chronic inflammation, as observed in a broad spectrum of degenerative musculoskeletal pathology.	28095751
Inflammation, musculoskeletal regeneration	Altered Intercellular Communication	Overall this work demonstrates a novel method for modulating cell response to inflammatory signaling that has applications in engineering cells delivered to inflammatory environments, and as a direct gene therapy to protect endogenous cells exposed to chronic inflammation, as observed in a broad spectrum of degenerative musculoskeletal pathology.	28095751
Inflammation Mediators	Altered Intercellular Communication	Here we show that microenvironmental cues, including inflammation-mediated resistance to adoptive T-cell immunotherapy, transcriptionally repress MITF via ATF4 in response to inhibition of translation initiation factor eIF2B.	28096186
Malignant Neoplasms	Altered Intercellular Communication	Of the 181 cases, histopathology was positive for malignancy in 166 (92%) patients and showed benign inflammation/fibrosis in 15 (8%) patients.	28097388
Hormone abnormality, Hypertrophy	Altered Intercellular Communication	Due to non-specific hormonal disorders and enlargement of the lesion, a right-sided laparoscopic adrenalectomy was performed.	28097642
Proteinuria, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The relationship between mean platelet volume and neutrophil/lymphocyte ratio with inflammation and proteinuria in chronic kidney disease.	28098108
Inflammation, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis, which develops as a result of inflammation, is the most important cause of morbidity and mortality in chronic kidney disease (CKD).	28098108
Proteinuria, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	In this study, we investigated the relationship of mean platelet volume (MPV) and neutrophil/lymphocyte ratio (NLR) with inflammation and proteinuria in patients with CKD Stage 3-4.	28098108
Inflammation, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	NLR may be a determinant of inflammation and atherosclerosis in patients with CKD.	28098108
Necrosis, Necrotizing granulomatous inflammation, Abscess, Suppuration, Hyperplasia	Altered Intercellular Communication	The histopathology in immunocompetent patients was characterized by pseudoepitheliomatous epidermal hyperplasia, intraepithelial abscesses, transepidermal elimination and dermal granulomatous inflammation accompanied by necrosis and suppuration.	28098393
Inflammation, Immunocompromised Host, Granuloma	Altered Intercellular Communication	The immunocompromised patients showed suppurative inflammation with little granuloma formation and numerous acid-fast bacilli.	28098393
Jaundice, Obstructive	Altered Intercellular Communication	Prognostic value of inflammation-based markers in patients with recurrent malignant obstructive jaundice treated by reimplantation of biliary metal stents: A retrospective observational study.	28099348
Inflammation, Communicable Diseases, Injury of lens, Hyphema, Hypopyon	Altered Intercellular Communication	No serious complications such as infection, hyphema, lens trauma or severe inflammation including hypopyon and AC fibrin formation were observed.	28100481
Inflammation, Necrosis	Altered Intercellular Communication	The IPA suggested that increased inflammation, immune activation with decreased necrosis and apoptosis preceded poor outcome.	28100627
Inflammation	Altered Intercellular Communication	BACKGROUND Increasing evidence suggests that cancer-associated inflammation is associated with poorer outcomes.	28100902
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	The neutrophil-to-lymphocyte ratio (NLR), considered as a systemic inflammation marker, is thought to predict prognoses in colorectal cancer.	28100902
Congenital pericardial cyst, Inflammation, Rupture, Chest Pain	Altered Intercellular Communication	Inflammation and Rupture of a Congenital Pericardial Cyst Manifesting Itself as an Acute Chest Pain Syndrome.	28100978
Congenital pericardial cyst, Inflammation, Chest Pain, Rupture	Altered Intercellular Communication	The suspected cause of the patient's chest pain was acute inflammation of a congenital pericardial cyst with subsequent rupture and resolution of symptoms.	28100978
Inflammation	Altered Intercellular Communication	Inflammation seems to be associated with the presence of a specific clinical subtype in PDLRRK2 that is characterized by a broad and more severely affected spectrum of motor and non-motor symptoms.	28102045
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	Hence, given the role of inflammation in the development of ALS, the high translational impact of the model, the known anti-inflammatory properties of these extracts, and the viability of their clinical use, these results suggest that the application of Wse and Mpe might represent a valuable pharmacological strategy to counteract the progression of ALS and related symptoms.	28102336
Inflammation	Altered Intercellular Communication	The pathological findings confirmed diverticulum penetration into the mesentery and severe inflammation at the site, with surrounding ectopic pancreas.	28102481
Diabetes Mellitus, Insulin-Dependent, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Cardiovascular risk in type 1 diabetes mellitus (T1DM) is associated with endothelial dysfunction, inflammation, and altered immunity.	28102614
Inflammation, Weight decreased	Altered Intercellular Communication	Systemic inflammation is suggested to be associated with weight loss.	28102709
Inflammation, Pre-Eclampsia	Altered Intercellular Communication	South African (SA) Black women have a high prevalence of preeclampsia and HIV, both conditions associated with increased inflammation.	28103790
Inflammation, Electrocardiogram: myocardial infarction (finding), Obesity, Visceral	Altered Intercellular Communication	Relationship key factor of inflammation and the development of complications in the late period of myocardial infarction in patients with visceral obesity.	28103807
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	These data suggest that type VI collagen turnover and elastin degradation by neutrophil elastase are associated with COPD-induced inflammation (eosinophil-bronchitis) and emphysema.	28103932
Necrotizing granulomatous inflammation, Aspergillus, Fungal	Altered Intercellular Communication	Biopsy of the transplanted kidney showed severe necrotizing granulomatous inflammation and fungal elements consistent with aspergillus species.	28104135
Autoimmune Diseases, Inflammation, Axonal degeneration	Altered Intercellular Communication	Multiple sclerosis (MS) is an autoimmune disease characterized by inflammation and axonal degeneration of the central nervous system and a leading cause of disability in young adults.	28104261
Celiac Disease, Have Autoimmune or Inflammatory Condition, Lymphoma, Gastrointestinal Stromal Sarcoma	Altered Intercellular Communication	Celiac disease (CD), an autoimmune inflammation of small intestine, has increasing prevalence in the elderly and may lead to lymphomas and gastrointestinal malignancies.	28104447
Inflammation	Altered Intercellular Communication	Participants had some natural teeth, periodontal inflammation, non-aggressive behaviour, no communicable diseases, were non-smokers and non-comatose.	28105737
Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	Outcomes were measured at baseline and 6 weeks, which included: inflammation (MGI, Lobene), bleeding (PBI, Loesche) and Plaque (Turesky).	28105737
Inflammation, Pneumonia	Altered Intercellular Communication	25-Hydroxy-Vitamin D Concentration Is Not Affected by Severe or Non-Severe Pneumonia, or Inflammation, in Young Children.	28106720
Communicable Diseases, Inflammation	Altered Intercellular Communication	Infection and inflammation did not alter the 25(OH)D concentration in young children with acute lower respiratory tract infections.	28106720
Refractory anemias, Rheumatoid Arthritis, Arthritis, Autoimmune Diseases	Altered Intercellular Communication	Rheumatoid Arthritis (RA) is a progressive autoimmune disease characterized by chronic joint inflammation and structural damage.	28107378
Crohn Disease, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Crohn's disease (CD) is a chronic mucosal inflammation that affects the intestinal barrier function, for example, by altering the intestinal permeability.	28107568
Inflammatory disease of mucous membrane	Altered Intercellular Communication	OHIG and EEN resulted in virtually similar reductions in the signs and symptoms of mucosal inflammation.	28107568
Inflammation, Intratumoral	Altered Intercellular Communication	GKRS-induced complications (intratumoral bleeding and tumoral tissue inflammation) occurred in 6% of the patients, of whom 4% were in the delayed group and 2% in the adjuvant group.	28108427
Inflammation, Arthritis, Atherosclerosis	Altered Intercellular Communication	Traditional cardiovascular risk factors or inflammation: Which factors accelerate atherosclerosis in arthritis patients?	28109577
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide (eNO) is a biomarker of airway inflammation and seems to precede respiratory symptoms, such as asthma, in childhood.	28109725
Airway structure	Altered Intercellular Communication	Identifying genetic determinants of postnatal eNO levels might aid in unraveling the role of eNO in epithelial function or airway inflammation and disease.	28109725
Inflammation, Atherosclerosis	Altered Intercellular Communication	18F-FDG PET imaging has become established for imaging inflammation in atherosclerosis in the aorta and carotid arteries.	28109921
Inflammation	Altered Intercellular Communication	The authors provide the first demonstration of successful, low-radiation (7.2 mSv) PET/MR imaging of inflammation and microcalcification activity in the coronary arteries.	28109921
Communicable Diseases, Inflammation	Altered Intercellular Communication	There are indications from experimental and observational studies that aspirin may reduce inflammation associated with infection.	28110287
Steatohepatitis, Fibrosis Assessment, Inflammation, Siderosis	Altered Intercellular Communication	Biopsy was obtained in all cases, grading liver steatosis, siderosis, inflammation, and fibrosis.	28110367
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Calculated fat fraction measurements showed significant differences (p < 0.001) among steatosis grades, being unaffected by the presence of inflammation or fibrosis (p >= 0.05).	28110367
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	Calculated R2* values were not different across grades of steatosis, inflammation, and fibrosis (p >= 0.05).	28110367
Hepatitis, Liver diseases, Steatohepatitis, Fibrosis Assessment, Siderosis	Altered Intercellular Communication	A MECSE-MR sequence simultaneously quantifies liver steatosis and siderosis, regardless coexisting liver inflammation or fibrosis, with high accuracy in a wide spectrum of diffuse liver disorders.	28110367
Inflammation, Chronic disease	Altered Intercellular Communication	To test the association of low-grade inflammation with socioeconomic status (SES) and determine the relative contribution of prevalent chronic diseases and health-related behaviours in explaining such association.	28110395
Inflammation, Chronic disease	Altered Intercellular Communication	Adiposity and body mass index showed a prominent role, while prevalent chronic diseases and conditions only marginally attenuated SES inequalities in inflammation.	28110395
Chronic lymphocytic inflammation, Pontine structure, Clippers, Chronic inflammatory disorder	Altered Intercellular Communication	Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) is a rare chronic inflammatory disorder of the central nervous system.	28110629
Deficit, Inflammation, Neurotoxicity Syndromes	Altered Intercellular Communication	The differential metabolites reflect pathophysiological processes of inflammation, energy deficit, oxidative stress, neurotoxicity, neuro excitation and injury.	28111353
Seroconversion, Hepatic inflammation, Hepatitis B	Altered Intercellular Communication	Hepatitis B e seroconversion, associated with preceding hepatic inflammation, marks the transition from immune active to residual phase in the natural disease history of chronic hepatitis B.	28111892
Hepatic inflammation, Hepatitis B	Altered Intercellular Communication	Recently, interleukin-27 has been reported to be associated with hepatic inflammation in hepatitis B infection.	28111892
Fibrosis Assessment, Hepatitis, VHL protein, human	Altered Intercellular Communication	Overexpression of VHL attenuated liver fibrosis, downregulated fibrogenic genes, and inhibited liver inflammation, apoptosis, and angiogenesis.	28112200
Inflammation	Altered Intercellular Communication	Myokines have anti-inflammatory properties and thereby reduce low-grade inflammation.	28112528
Inflammation, Toxic effect	Altered Intercellular Communication	Two dietary polyphenols, fisetin and luteolin, reduce inflammation but augment DNA damage-induced toxicity in human RPE cells.	28113103
methyldopa, Inflammation, Chronic disease	Altered Intercellular Communication	In recent years, several studies have investigated their potential benefits for treating chronic diseases associated with prolonged inflammation and excessive oxidative stress, such as age-related macular degeneration (AMD).	28113103
Inflammation, Mortality, Premature	Altered Intercellular Communication	Our study suggests that inflammation pathways reported by these biomarkers only have a limited role in causing premature RBC death.	28114136
Pain Distress Question, Inflammation	Altered Intercellular Communication	Pain perception, intraoral inflammation (InIn), and extraoral inflammation (ExIn) data were collected 3, 7, and 14 days after surgery.	28114265
Inflammation, Metabolic Syndrome X, Neurotoxicity Syndromes, Chronic Polyneuropathy	Altered Intercellular Communication	Metabolic Syndrome, Neurotoxic 1-Deoxysphingolipids and Nervous Tissue Inflammation in Chronic Idiopathic Axonal Polyneuropathy (CIAP).	28114358
Inflammation, Neurotoxicity Syndromes, Disease of capillaries, Metabolic Syndrome X	Altered Intercellular Communication	We studied the potential role of the metabolic syndrome, neurotoxic 1-deoxysphingolipids (1-deoxySLs), microangiopathy and inflammation in sural nerve biopsies.	28114358
prostatitis	Altered Intercellular Communication	Prevalence of chronic prostatic inflammation based on clinical diagnostic criteria in a real-practice setting: a nation-wide observational study.	28114753
Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	Chronic prostatic inflammation has a key role in the pathogenesis and progression of benign prostatic hyperplasia (BPH).	28114753
Inflammation	Altered Intercellular Communication	Thus, the identification of patients with chronic inflammation is mandatory for Urologists.	28114753
Lower Urinary Tract Symptoms, prostatitis	Altered Intercellular Communication	Patients were allocated into four diagnosis group: patients with BPH; patients with BPH and chronic prostate inflammation; patients with chronic prostate inflammation alone; and patients with lower urinary tract symptoms (LUTS) due to other causes.	28114753
Inflammation, prostatitis	Altered Intercellular Communication	BPH diagnosis with or without concomitant prostate inflammation was more frequent in older patients, while inflammation alone was prevalent in younger patients.	28114753
Communicable Diseases, Inflammation, Calcified (qualifier), Acute and chronic inflammation	Altered Intercellular Communication	Predictive factors for diagnosis of inflammation in all patients, regardless of age, were normal urinary flow (OR=2.73) and proved in-fection (OR=5.90), while in older patients (>61 years) diagnosis of chronic prostatic inflammation was specifically predicted by higher PSA values (>=4 ng/mL; OR=2.91), normal prostate volume (OR=10.23), mild symptoms (IPSS <8; OR=1.84), presence of intraprostatic calcifications (OR=4.55), and the combination of both infection and calcifications (OR=10.79).	28114753
prostatitis	Altered Intercellular Communication	In daily practice, the presence of chronic prostatic inflammation is underestimated.	28114753
Lower Urinary Tract Symptoms, prostatitis	Altered Intercellular Communication	A stricter application of established diagnostic criteria suggested would increase the detection rate of chronic prostatic inflammation and potentially change the therapeutic approach in many patients with LUTS.	28114753
Granulomatous inflammation	Altered Intercellular Communication	Samples sent from material curetted from sinus yielded no organism but histopathology reported granulomatous inflammation.	28114858
Blindness, GCA gene, Giant Cell Arteritis, Cerebrovascular accident, Have Autoimmune or Inflammatory Condition, Aortic Arch Syndromes	Altered Intercellular Communication	Giant cell arteritis (GCA) causes autoimmune inflammation of the aorta and its large branches, resulting in aortic arch syndrome, blindness, and stroke.	28115719
ARCN1 gene, Inflammation	Altered Intercellular Communication	B-IMT was significantly associated with systemic inflammation (interleukin-6 [IL-6]; r=0.365, P=0.006) and ADMA (r=0.331, P=0.013) in COPD.	28115840
ARCN1 gene, Inflammation	Altered Intercellular Communication	B-IMT is significantly increased in patients with COPD and is associated with systemic inflammation and ADMA levels.	28115840
Overweight	Altered Intercellular Communication	Ferritin Is a Marker of Inflammation rather than Iron Deficiency in Overweight and Obese People.	28116148
Inflammation, Overweight	Altered Intercellular Communication	To investigate the role of ferritin in overweight and obese people, either as a marker of inflammation or iron deficiency.	28116148
Inflammation, Ferritin, Overweight	Altered Intercellular Communication	Ferritin is a marker of inflammation rather than iron status in overweight and obese people.	28116148
Inflammation	Altered Intercellular Communication	Platelet endothelial cell adhesion molecule-1 (PECAM-1) plays a key role in the transendothelial migration of circulating leukocytes during inflammation and in the maintenance of vascular endothelial integrity.	28116228
Arthritis	Altered Intercellular Communication	* DCE-MRI biomarkers are feasible in large multicentre studies of joint inflammation.	28116513
Neurogenic Inflammation, Pruritus	Altered Intercellular Communication	This vehicle-controlled, double-blinded study investigated the effect of topical capsaicin 8% after 1- and 24-h application on evoked itch, neurogenic inflammation and itch-associated dysaesthesia.	28117875
Neurogenic Inflammation	Altered Intercellular Communication	Furthermore, 24-h capsaicin pretreatment abolished punctuate hyperknesis and lowered histamine-induced neurogenic inflammation but did not affect weal reactions.	28117875
PROS1 gene, Inflammation, Refractory anemias	Altered Intercellular Communication	However, patients with PsA in remission are characterised by a higher degree of residual synovial inflammation than patients with RA in remission, despite PDUS negativity under TNF inhibition.	28119289
Inflammation, Thrombosis, Stasis, Heart failure	Altered Intercellular Communication	Thrombosis within the vascular system in relation to inflammation and stasis is potentially associated with poor prognosis in patients with heart failure.	28120034
Inflammation, Congenital Disorders, Neoplasms, Bone Marrow Diseases, Infection, Post-Traumatic Stress Disorder	Altered Intercellular Communication	These include congenital disorders, chronic inflammation, neoplasms, infections, and posttraumatic conditions that could all result in CVJ compression and myelopathy Endoscopic-assisted procedures have been further developed for CVJ decompression and they have now become conventional approaches.	28120062
Esophagogastric Junction, Primary malignant neoplasm	Altered Intercellular Communication	Bisphosphonate, tetracycline and spironolactone use has been shown to increase gastro-oesophageal inflammation, an accepted risk factor for cancer.	28120338
Inflammation, Dermatitis	Altered Intercellular Communication	Topical cosmetic agents may play a role in the management of facial seborrheic dermatitis by reducing inflammation and scale production.	28121079
Inflammation, Osteoporosis	Altered Intercellular Communication	Inflammation as a contributing factor among postmenopausal Saudi women with osteoporosis.	28121926
Inflammation, Osteoporosis	Altered Intercellular Communication	Findings of the present study implicate a role for cytokine pattern-mediated inflammation in patients with osteoporosis.	28121926
Osteoporosis, Osteopenia	Altered Intercellular Communication	Recently, the most prevalent form of clinically significant osteopenia and osteoporosis involves various inflammatory conditions.	28121926
Inflammation, Fracture, Diabetes Mellitus	Altered Intercellular Communication	Not only aging, low bone mineral density and history of previous fracture, but also diabetes mellitus and inflammation are regarded as risk factors for fracture.	28122172
Autoimmune Diseases, Inflammation, Bone Diseases, Hyperostosis, Sternocostoclavicular	Altered Intercellular Communication	The high prevalence of autoimmune disease in patients with sternocostoclavicular hyperostosis and their first-degree relatives suggests that autoimmunity may play a role in the still elusive pathophysiology of the intriguing osteogenic response to inflammation observed in this rare bone disorder.	28122596
Cartilage destruction, Inflammation	Altered Intercellular Communication	Inflammation is a major cause of cartilage destruction and leads to the imbalance of metabolic activities in the arthritic joint.	28122611
Inflammation	Altered Intercellular Communication	This is the first study identifying a specific role for PEDF in joint inflammation and highlights the multi-faceted activities of PEDF.	28122611
Inflammation, Disorder of tendon	Altered Intercellular Communication	Growing evidence supports a key role for inflammation in the onset and progression of tendinopathy.	28122639
Inflammation, Disorder of tendon	Altered Intercellular Communication	Persistent stromal fibroblast activation may be implicated in the development of chronic inflammation and recurrent tendinopathy.	28122639
Inflammation, Periodontitis	Altered Intercellular Communication	Periodontitis is a chronic oral pathology caused by impaired immune response against oral bacteria resulting in tissue inflammation and damage.	28122660
Enteritis, physiopathological	Altered Intercellular Communication	Environmental enteric dysfunction (EED), a condition characterized by small intestine inflammation and abnormal gut permeability, is widespread in children in developing countries and a major cause of growth failure.	28122695
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Recent studies have demonstrated the role of systemic inflammation in the development and progression of cancer.	28124528
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Monitoring total-body inflammation and damage in joints and entheses: the first follow-up study of whole-body magnetic resonance imaging in rheumatoid arthritis.	28125360
Inflammation, Edema of bone marrow, Synovitis, Erosion of bone, Enthesitis	Altered Intercellular Communication	The intrareader agreement was high for bone marrow oedema (BMO), bone erosion (80-100%), and enthesitis (77-100%), and slightly lower for synovitis and soft tissue inflammation (50-100%).	28125360
Inflammation, Synovitis	Altered Intercellular Communication	All synovitis, BMO, and soft tissue inflammation counts decreased numerically during treatment.	28125360
MTA2 gene, Inflammation, Pelvic Inflammatory Disease	Altered Intercellular Communication	Pelvic inflammatory disease (PID) is a clinical syndrome of the female reproductive tract characterized by inflammation of the endometrium, fallopian tubes, or peritoneum (1).	28125569
Pneumonitis	Altered Intercellular Communication	We have previously shown that mice lacking the ability to generate Vasoactive Intestinal Peptide (VIP) develop spontaneous PH, pulmonary arterial remodeling and lung inflammation.	28125639
Inflammation, Helicobacter pylori, Stomach Carcinoma, Communicable Diseases, precancerous lesions	Altered Intercellular Communication	Helicobacter pylori (H. pylori) infection induces inflammation of the gastric mucosa, which may progress to precancerous lesions leading to gastric cancer.	28125638
Presenile dementia, Inflammation, Mental disorders	Altered Intercellular Communication	DMN brain systems have been implicated in diverse social, cognitive, and affective processes, as well as risk for forms of dementia and psychiatric disorders that associate with systemic inflammation.	28126500
Inflammation	Altered Intercellular Communication	These novel findings offer evidence for a unique association between a marker of systemic inflammation (IL-6) and ACC and mPFC functional connectivity within the DMN, a network that may be important for linking aspects of immune function to psychological and behavioral states in health and disease.	28126500
Anemia	Altered Intercellular Communication	Elevated Plasma Neutrophil Gelatinase-Associated Lipocalin Level as a Risk Factor for Anemia in Patients with Systemic Inflammation.	28127551
Inflammation, Anemia	Altered Intercellular Communication	This study investigated the relationships between plasma NGAL levels and indices of anemia in 187 patients with systemic inflammation.	28127551
Inflammation, Anemia	Altered Intercellular Communication	In conclusion, enhanced NGAL production may contribute to the development of anemia in patients with systemic inflammation.	28127551
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	T2 inflammation of chronic rhinosinusitis with nasal polyps (CRSwNP) may be influenced by epithelial cytokines release (TSLP, IL-25, and IL-33).	28127565
Inflammation, Organ Dysfunction Scores, Acute Cholecystitis	Altered Intercellular Communication	According to the Tokyo Guidelines, severity of acute cholecystitis is divided into three grades based on the degree of inflammation and the presence of organ dysfunction.	28127715
Liver carcinoma	Altered Intercellular Communication	Lymphocyte to monocyte ratio and neutrophil to lymphocyte ratio are superior inflammation-based predictors of recurrence in patients with hepatocellular carcinoma after hepatic resection.	28127774
Liver carcinoma, FAM126A gene	Altered Intercellular Communication	The purpose of this study was to investigate which inflammation-based marker more accurately predict recurrence in patients receiving hepatectomy for hepatocellular carcinoma (HCC).	28127774
Inflammation, muscle mass, Skeletal muscle hypertrophy	Altered Intercellular Communication	Resistance training during hospitalization increases skeletal muscle mass, and patients with high levels of systemic inflammation demonstrate less ability to increase or preserve muscle mass in response to resistance training during illness.	28129234
Inflammation, Ulceration, CTCAE, Granuloma, Crohn Disease	Altered Intercellular Communication	Both patients had evidence of inflammation, ulceration, and granulomas consistent with Crohn's disease, and responded well to immunosuppression.	28129697
Inflammation	Altered Intercellular Communication	Abnormal parameters associated with systemic inflammation, such as higher plateletcrit level, may facilitate the development of TASS.	28130690
Inflammation	Altered Intercellular Communication	Low-grade chronic inflammation is associated with several chronic conditions, and diet is known to play a role in chronic inflammation.	28130829
Inflammation, Malignant Neoplasms, Neoplasms	Altered Intercellular Communication	Deleted in malignant brain tumours 1 (DMBT1) exerts functions in the regulation of epithelial differentiation and inflammation and has been proposed as a tumour suppressor.	28130841
Inflammation, Fibrosis Assessment, Hypoxia	Altered Intercellular Communication	Markers of hypoxia, adipo- and angiogenesis, inflammation and fibrosis were analysed in AT and serum.	28131740
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Resting AT blood flow was higher in OSAS compared to controls (108.5+-22.7 vs. 78.9+-24.9au, P<0.005) and strongly associated with inflammation markers IL-6 and MCP-1.	28131740
Inflammation, Fibrosis Assessment, Sleep Apnea, Obstructive	Altered Intercellular Communication	AT of OSAS subjects showed increased inflammation (TNFA P=0.049) and fibrosis (COL3A1 P=0.02), a trend of higher HIF1A expression (P=0.06) and reduced adipogenesis (PPARG P=0.006).	28131740
Inflammation, Fibrosis Assessment, Structure of bronchial artery	Altered Intercellular Communication	In contrast, both lungs showed clear signs of chronic inflammation and fibrosis that could be the cause of bronchial artery hypertrophy.	28132091
Inflammation, Subretinal deposits	Altered Intercellular Communication	There are no disease-altering therapies for dry AMD, which is characterized by accumulation of subretinal drusen deposits and complement-driven inflammation.	28132833
Inflammation, Heart failure	Altered Intercellular Communication	Background In patients with heart failure, inflammation has been associated with worse functional capacity, but it is uncertain whether it could affect their response to exercise training.	28134562
Drug Eruptions, Inflammation, Parakeratosis, Spongiosis	Altered Intercellular Communication	In several skin biopsies, histologic features supporting a lichenoid drug eruption were present, including parakeratosis, spongiosis, periadnexal/perivascular inflammation, and eosinophils.	28134729
Inflammation, Dental Plaque	Altered Intercellular Communication	Free PAI-1 and TAFI stabilize active plaque area by inhibition of fibrinolysis and inflammation.	28135035
Inflammation	Altered Intercellular Communication	CD68 was highly associated with VWF, PAI-1 and especially TAFI, underlining the role of macrophages in fibrinolytic activity and inflammation.	28135035
Inflammation, Dental Plaque	Altered Intercellular Communication	Conclusion The abundance of free PAI-1 and TAFI in the plaque may inhibit plasmin generation and thereby counteract plaque destabilization by fibrinolysis, cell migration and inflammation.	28135035
Lymphedema, Cellulitis	Altered Intercellular Communication	Lymphedema is an irreversible inflammatory condition caused by accumulated lymph fluid and is associated with chronic swelling and increased risk of cellulitis.	28135124
Inflammation, Chronic pain	Altered Intercellular Communication	They can result in chronic inflammation, reduced mobility, and chronic pain.	28135201
Inflammation, Attempt	Altered Intercellular Communication	Blunted HPA axis activity prior to suicide attempt and increased inflammation in attempters.	28135675
Inflammation, Gain, Colorectal Carcinoma	Altered Intercellular Communication	The current study is designed to gain a better understanding of the role of a healthy diet aimed at dampening inflammation and oxidative stress on long-term disease outcomes and survival in colorectal cancer patients.	28137255
allergic inflammation, Eosinophilic inflammation	Altered Intercellular Communication	Recently, the innate Th2 response is revealed to induce eosinophil infiltration in allergic inflammation, however the role of the innate Th2 response has not been studies in AERD.	28137499
palladium, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Given that inflammation plays a role in both PD and depression, it is intriguing that peripheral p11 levels are altered in immune cells in both conditions.	28137881
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Thus, MPO-ANCA may promote inflammation by reducing the secretion of antiinflammatory IL-10 from monocytes, and MPO-ANCA can alter the development of macrophages and T cells to potentially promote fibrosis.	28138552
Inflammation, Neck Pain	Altered Intercellular Communication	The neck pain is due to inflammation caused by calcium hydroxyapatite crystal deposition in the tendons on the longus colli muscles.	28139306
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Oxidized low-density lipoprotein, lipid and calcium aggregates reveal oxidative stress and inflammation in the conjunctiva of glaucoma patients.	28139882
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	The lipid-mediated alterations suggested the presence of oxidative stress and inflammation in the conjunctiva of glaucoma patients.	28139882
Inflammation, Failure (biologic function)	Altered Intercellular Communication	The present data further support the role of oxidative stress and inflammation in the wound healing process leading to excessive scarring and failure in DS surgery.	28139882
Portal vein structure, Inflammation	Altered Intercellular Communication	Portal vein stenosis develops due to different causes including postoperative inflammation and oncological processes.	28143477
Inflammation, B-Cell Lymphomas	Altered Intercellular Communication	Epstein-Barr virus (EBV) is associated with B-cell lymphoma in various conditions, such as immunodeficiency and chronic inflammation.	28143608
Inflammation, Asthma	Altered Intercellular Communication	Cluster 2 was composed of patients with a mix of patients with nonsevere and severe asthma with marginal inflammation who exhibited airway luminal narrowing without wall thickening.	28143694
Adverse reaction to drug, Acute inflammation, Edema	Altered Intercellular Communication	When sodium aescinate is given to surgical inpatients to treat postoperative inflammation and oedema, adverse drug reactions and drug-drug interactions must be closely monitored.	28144968
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Smoking was associated with less radiographic hand OA whereas alcohol consumption was associated with present joint inflammation in hand OA.	28145147
Pneumonitis	Altered Intercellular Communication	Elevated GDF-15 contributes to pulmonary inflammation upon cigarette smoke exposure.	28145442
Inflammation, Cachexia	Altered Intercellular Communication	Growth differentiation factor (GDF)-15, a member of the TGF-b superfamily, is involved in inflammation, mucus secretion, and cachexia.	28145442
Pneumonitis	Altered Intercellular Communication	Importantly, GDF-15 deficiency attenuated the CS-induced pulmonary inflammation.	28145442
Pneumonitis	Altered Intercellular Communication	These results suggest that increased GDF-15-as observed in lungs of smokers and patients with COPD-contributes to CS-induced pulmonary inflammation.	28145442
Acute Kidney Injury, CTCAE, Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	Serum prealbumin is a clinically relevant indicator of nutritional status and inflammation in patients with acute kidney injury (AKI).	28145481
Inflammation, Muscular Atrophy, Abnormal degeneration	Altered Intercellular Communication	Markers of vascularity; inflammation; fat distribution; and muscle atrophy, degeneration, and regeneration were quantified.	28145949
Inflammation, Atrophic, Muscle (organ)	Altered Intercellular Communication	Dramatic degeneration and inflammation of the rotator cuff muscles are characteristics of the most chronic and severe rotator cuff disease states, suggesting that muscle loss is more complicated than, and distinct from, the simple atrophy found in less severe cases.	28145949
Inflammation, Myocardial dysfunction	Altered Intercellular Communication	Up-regulation of miR-135a could aggravate sepsis-induced inflammation and myocardial dysfunction via activation of p38 MAPK/NF-kB pathway.	28147298
Inflammatory Bowel Diseases, Inflammation, Infectious colitis, Ulcerative Colitis	Altered Intercellular Communication	Histological evaluation revealed acute inflammation without architectural distortion consistent with either acute infectious colitis or new inflammatory bowel disease, favoring UC.	28147350
Kidney Failure, Chronic	Altered Intercellular Communication	Further evaluation of novel hormonal agents in end-stage renal disease patients should be encouraged as this population is typically excluded from clinical trials.	28147927
F11 gene, vascular inflammations	Altered Intercellular Communication	The resulting vascular inflammation and dysfunction was mediated by activation of thrombin-driven factor XI (FXI) feedback, independent of factor XII.	28148841
Hypertension, CTCAE, physiopathological, Cardiovascular Diseases	Altered Intercellular Communication	Our results outline a coagulation-inflammation circuit that promotes vascular dysfunction, and highlight the possible utility of FXI-targeted anticoagulants in treating hypertension, beyond their application as antithrombotic agents in cardiovascular disease.	28148841
Inflammation, cervical cancer	Altered Intercellular Communication	Predictive value of hematological markers of systemic inflammation for managing cervical cancer.	28148894
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and red cell distribution width (RDW) are markers of systemic inflammation with prognostic significance for cancers.	28148894
Inflammation Mediators, IL13 gene, Chronic disease	Altered Intercellular Communication	Allergic rhinitis is a common chronic disorder characterized by immunoglobulin E-mediated inflammation.	28149331
Inflammation, Blood Clot, Hypoxia	Altered Intercellular Communication	The aim of this study was to allocate distinct cellular processes playing a role in thrombus resolution, such as inflammation, hypoxia, proliferation, apoptosis and angiogenesis, to different stages of thrombofibrotic remodelling.	28150849
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Hematologic parameters of systemic inflammation are receiving attention as promising prognostic indicators in cancer patients.	28151879
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	In recent years, the predictive and prognostic value of the red cell distribution width (RDW) as an indicator of inflammation has been shown in many cardiovascular diseases.	28151892
vascular inflammations	Altered Intercellular Communication	Enhanced vascular inflammation is also implicated as one of the pathophysiologic mechanisms in CAD.	28153212
Sleep-Disordered Breathing, Inflammation	Altered Intercellular Communication	Nocturnal intermittent hypoxia and short sleep duration were independently associated with elevated serum CRP level in CAD patients, suggesting that both SDB and sleep shortage are associated with enhanced inflammation in CAD patients.	28153212
Inflammation, Anemia	Altered Intercellular Communication	Approximately two-thirds of anemia in American elderly is caused by chronic inflammation or is unexplained.	28153527
Inflammation	Altered Intercellular Communication	A potential contributing factor may include air pollution exposures, which have been shown to increase systemic inflammation and affect erythropoiesis.	28153527
Inflammatory abnormality of the eye	Altered Intercellular Communication	Remission was defined as absence of progressive scarring and active ocular inflammation for >= 2 months.	28154932
Inflammation	Altered Intercellular Communication	Systemic inflammation was suggested as an important prognostic factor for outcomes.	28154994
Heart failure, myocardial injury	Altered Intercellular Communication	Acute Effects of Implantable Cardioverter-Defibrillator Shocks on Biomarkers of Myocardial Injury, Apoptosis, Heart Failure, and Systemic Inflammation.	28156007
Inflammation, myocardial injury	Altered Intercellular Communication	Biomarkers indicative of myocardial injury, inflammation, and apoptosis were measured before and after implantation, and compared between patients receiving DFT (DFT+) to those not (DFT-).	28156007
myocardial injury	Altered Intercellular Communication	Implantable cardioverter-defibrillator (ICD) shocks are potentially associated with myocardial injury, altered hemodynamics, apoptosis, and inflammatory signaling.	28156007
Inflammation, Neoplasms	Altered Intercellular Communication	This may be secondary to other processes such as tumor biology and inflammation.	28156177
Inflammation, Carcinogenesis	Altered Intercellular Communication	Single-nucleotide polymorphisms (SNPs) in cytokine genes can affect gene expression and thereby modulate inflammation and carcinogenesis.	28157220
Inflammation, Uveitis	Altered Intercellular Communication	Anterior and non-granulomatous uveitis was the most common types of inflammation.	28157425
Cataract, Inflammation	Altered Intercellular Communication	A longer duration of symptoms as well as anterior inflammation demonstrated an increased risk for cataract formation.	28157425
Inflammation	Altered Intercellular Communication	In addition, patients suffering from CF display chronic inflammation that contributes to the pathogenesis of CF.	28158236
Inflammation	Altered Intercellular Communication	Recent work suggests that CF patients have a reduced capacity to biosynthesize specialized pro-resolving lipid mediators (SPMs), which contributes to the development and duration of the unwanted inflammation.	28158236
Airway structure	Altered Intercellular Communication	Alterations in the metabolism of arachidonic acid (AA) and docosahexaenoic acid (DHA) to specialized pro-resolving mediators (SPMs), like lipoxins (LXs), maresins (MaRs), protectins (PDs) and resolvins (Rvs), may play a major role on clinical impact of airway inflammation in CF.	28158236
Parakeratosis, Intraepithelial Lymphocytosis, Acute inflammation, Bacterial resistance	Altered Intercellular Communication	Important histologic clues included superficial and detached fragments of desquamated and hyper-pink parakeratosis, acute inflammation, intraepithelial lymphocytosis, dead keratinocytes, and bacterial overgrowth.	28158394
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Regional Gene Expression of Inflammation and Oxidative Stress Responses Does Not Predict Neurodegeneration in Aging.	28158670
Airway structure	Altered Intercellular Communication	Arsenic exposure alters lung function and airway inflammation in children: A cohort study in rural Bangladesh.	28159392
Airway structure, Reduced Device Function	Altered Intercellular Communication	We aim to examine whether prenatal and childhood arsenic exposure is associated with reduced lung function and increased airway inflammation in school-aged children.	28159392
Airway structure, Impaired lung function	Altered Intercellular Communication	In conclusion, our findings suggest that prenatal arsenic exposure is related to impaired lung function, while childhood exposure may increase airway inflammation, particularly in boys.	28159392
Inflammation, Thrombosis, Cardiovascular Diseases	Altered Intercellular Communication	Particulate and gaseous pollutants on inflammation, thrombosis, and autonomic imbalance in subjects at risk for cardiovascular disease.	28159399
Presenile dementia, Inflammation	Altered Intercellular Communication	Many studies have investigated the association between markers for peripheral inflammation and risk of dementia, but the results have been conflicting.	28159467
Cessation of life, Inflammation, Presenile dementia, Cerebrovascular accident	Altered Intercellular Communication	A Cox proportional hazard model and Fine and Grays model were adjusted for stroke and competing risk of death to estimate the association between inflammation and development of dementia.	28159467
Inflammation, Neoplasms, Fibrosis Assessment, Hepatitis C, FAM126A gene	Altered Intercellular Communication	We demonstrate that tumour suppressor protein tyrosine phosphatase receptor delta (PTPRD) is impaired by HCV infection in vivo and in HCC lesions of paired liver biopsies independent from tissue inflammation or fibrosis.	28159835
Inflammation, Chronic Kidney Diseases, Obesity	Altered Intercellular Communication	Metabolically healthy obesity and incident chronic kidney disease: The role of systemic inflammation in a prospective study.	28160438
Inflammation, Units Of Measure - Siemens, Chronic Kidney Diseases, Obesity	Altered Intercellular Communication	To investigate the association between the metabolically healthy obesity (MHO) phenotype and incident chronic kidney disease (CKD) in a Chinese population and whether systemic inflammation affects this association.	28160438
Inflammation, Units Of Measure - Siemens, Chronic Kidney Diseases	Altered Intercellular Communication	MHO was significantly associated with incident CKD, and the level of systemic inflammation partially explained this association.	28160438
Inflammation	Altered Intercellular Communication	Aging is associated with a decline in autophagy and a state of low-grade inflammation which further affects apoptosis and autophagy.	28160545
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Importantly, we found no correlation between serum ferritin levels and the inflammation marker C-reactive protein (CRP) in prostate cancer patients.	28160568
Inflammation, Traumatic injury	Altered Intercellular Communication	Triester glycerol oxide gel (Protefix(r) Queisser Pharma, Germany) is a new topical agent that has the property of adherence to the oral mucosa by forming a lipid film which protects against mechanical trauma and may help to reduce oral tissue moisture loss and inflammation.	28160585
Inflammation	Altered Intercellular Communication	These results show new possible mechanisms connecting androgens to insulin resistance and chronic inflammation.	28161330
Cerebral Amyloid Angiopathy, Inflammation, Granulomatous, Vasculitis, CTCAE, Vasculitis, Abra (invertebrate)	Altered Intercellular Communication	Amyloid-b-related angiitis (ABRA) is a rare complication of cerebral amyloid angiopathy in which amyloid-b deposition in the leptomeningeal and cortical vessels is associated with vasculitis characterized by transmural lymphohistiocytic, often granulomatous, inflammation.	28161339
Presenile dementia, Inflammation, Impaired cognition	Altered Intercellular Communication	Studies on markers of inflammation in subjects with mild cognitive impairment or AD dementia provided inconsistent results.	28161476
Inflammation, Data types - Address, Trauma, Nervous System	Altered Intercellular Communication	an AD CSF biomarker profile) and to investigate associations of inflammation markers with CSF biomarkers of amyloid, tau pathology, and neuronal injury.	28161476
Inflammation, Vascular System Injuries	Altered Intercellular Communication	The best predictive models included 8 serum or 3 CSF neuroinflammatory markers related to cytokine mediated inflammation, vascular injury, and angiogenesis.	28161476
Inflammation, Vascular System Injuries	Altered Intercellular Communication	Our results suggest that inflammation, vascular injury, and angiogenesis as reflected by CSF markers are closely related to cerebral tau pathology.	28161476
Inflammation, Traumatic injury	Altered Intercellular Communication	Gender and a proxy of menopause were associated with various features of inflammation and injury in DILI.	28161910
Communicable Diseases, Inflammation	Altered Intercellular Communication	Although no infection or inflammation occurred at the surgical site, the patient requested removal of the PPE implant for aesthetic reasons alone at 1 year after the surgery.	28162855
Inflammation	Altered Intercellular Communication	Maltodextrin/ascorbic acid stimulates wound closure by increasing collagen turnover and TGF-b1 expression in vitro and changing the stage of inflammation from chronic to acute in vivo.	28162862
Inflammation, artery calcification	Altered Intercellular Communication	Inflammation plays a central role in atherogenesis and artery calcification.	28162903
Heart failure	Altered Intercellular Communication	Plasma Zonulin and its Association with Kidney Function, Severity of Heart Failure, and Metabolic Inflammation.	28164545
Inflammation	Altered Intercellular Communication	Recent work also suggests zonulin to represent a general regulator of tissue barriers and a player in metabolic inflammation.	28164545
Inflammation, Chronic heart failure, Congestive heart failure	Altered Intercellular Communication	Here, we investigated the associations of zonulin with chronic heart failure (CHF), kidney function, and metabolic inflammation.	28164545
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Congestive heart failure	Altered Intercellular Communication	Our study indicates zonulin involvement in metabolic inflammation in T2D, but no association with disease status in CHF.	28164545
Pneumonitis	Altered Intercellular Communication	In this study, we investigated potential changes in BTLA expression on lymphocytes in patients with severe CAP and determined how BTLA expression affects a model of LPS-induced acute lung inflammation.	28164546
Pneumonitis	Altered Intercellular Communication	The percentages of circulating BTLA+CD4+ lymphocytes were determined in patients with severe CAP and in an LPS-induced acute lung inflammation model.	28164546
Pneumonitis	Altered Intercellular Communication	The percentages of circulating BTLA+CD4+ lymphocytes were significantly higher in patients with severe CAP and in mice with LPS-induced acute lung inflammation than in the control groups.	28164546
Pneumonitis	Altered Intercellular Communication	After treatment with either dexamethasone or the agonistic anti-BTLA antibody 6A6, BTLA expression was significantly higher than that in the control mice with LPS-induced acute lung inflammation.	28164546
Sepsis, Cessation of life	Altered Intercellular Communication	Prognostic Value of Dynamic Monitoring of Cellular Immunity and HMGB1 in Severe Sepsis: Delayed Chronic Inflammation may be the Leading Cause of Death in Late Severe Sepsis.	28164547
Sepsis, Inflammation, Immune System Diseases, Cessation of life	Altered Intercellular Communication	Patients with severe sepsis present with cellular immune dysfunction and persistent chronic inflammation, both of which may lead to death in the late phase of severe sepsis.	28164547
Sepsis, Inflammation	Altered Intercellular Communication	Dynamic monitoring of indicators of cellular immunity and HMGB1 is useful for evaluating the immune status, chronic inflammation processes, and prognoses of patients with severe sepsis.	28164547
Thoracic Injuries	Altered Intercellular Communication	Modulation of the Redox Expression and Inflammation Response in the Critically Ill Polytrauma Patient with Thoracic Injury.	28164593
Primary malignant neoplasm	Altered Intercellular Communication	Platelet to lymphocyte ratio (PLR) is widely used as an inflammation-related cancer biomarker.	28164624
Gastrointestinal inflammation	Altered Intercellular Communication	Fecal calprotectin is a noninvasive screening marker for intestinal inflammation.	28164652
airway disease, Inflammation, Smooth muscle (tissue), mucus secretion	Altered Intercellular Communication	Asthma is a chronic airway disease characterized by inflammation, mucus hypersecretion and abnormal airway smooth muscle (ASM) contraction.	28165446
Cessation of life, Crohn Disease-like Reaction	Altered Intercellular Communication	Moderate/severe peritumoral diffuse lymphoid inflammation and Crohn's disease-like reaction were associated with significantly reduced risks of CRC-specific death [adjusted hazard ratio (HR) 0.48, 95% confidence interval (CI) 0.31-0.76, and HR 0.60, 95% CI 0.42-0.84, respectively].	28165633
Inflammation	Altered Intercellular Communication	Postoperative management with sinonasal debridement and combined saline/corticosteroid nasal irrigation may help to improve surgical success in patients with increased post-radiotherapy mucosal inflammation.	28165837
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Objective To assess the level of C-reactive protein in acute appendicitis and to relate the quantitative measurement with degree of inflammation of appendix.	28166068
Inflammation, Electrocardiogram: myocardial infarction (finding), Cerebrovascular accident	Altered Intercellular Communication	Secondary outcomes include: (1) mean change in systolic BP; (2) control of other vascular risk factors including lipids and hemoglobin A1c, (3) inflammation (C reactive protein [CRP]), (4) medication adherence, (5) lifestyle factors (smoking, diet, and physical activity), (6) estimated relative reduction in risk for recurrent stroke or myocardial infarction (MI), and (7) cost-effectiveness of the intervention versus usual care.	28166784
Inflammation, Primary malignant neoplasm, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic disease	Altered Intercellular Communication	Chronic low-grade inflammation has been recognised as a key underlying mechanism for several chronic diseases, including cancer and CVD.	28166841
Inflammation	Altered Intercellular Communication	Nutrition represents a host of key modifiable factors that influence chronic inflammation.	28166841
Inflammation, Observation Method - Coagulation, Thrombosis	Altered Intercellular Communication	Associations between ambient wood smoke and other particulate pollutants and biomarkers of systemic inflammation, coagulation and thrombosis in cardiac patients.	28167447
Inflammation, Observation Method - Coagulation, Thrombosis	Altered Intercellular Communication	Our study examined associations between ambient levels of a marker of wood smoke (Delta-C) and other particulate air pollutants and biomarkers of inflammation, coagulation and thrombosis.	28167447
Inflammation, Observation Method - Coagulation, Impaired T cell function	Altered Intercellular Communication	Increases in PM2.5, BC, AMP, and UFP concentrations in the previous 96h were also associated with adverse changes in markers of systemic inflammation and coagulation, but not with markers of endothelial cell dysfunction or platelet activation.	28167447
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	However, it is known that Th17 cells exhibit considerable plasticity, particularly at sites of autoimmune inflammation.	28167631
Inflammation, Nonocclusive coronary artery atherosclerosis	Altered Intercellular Communication	We aimed to investigate whether markers of lipid metabolism, inflammation and kidney function could predict non-obstructive coronary artery disease (CAD) determined by coronary CTA, in a low-to-intermediate-risk group.	28168796
Tears body substance, Inflammation, Glaucoma, CTCAE, Dryness of eye	Altered Intercellular Communication	Determination of inmune response and inflammation mediators in tears: Changes in dry eye and glaucoma as compared to healthy controls.	28169068
Inflammation, Pain Distress Question, Structure of articular cartilage, Traumatic injury, Degenerative disorder	Altered Intercellular Communication	Loss of articular cartilage from ageing, injury or degenerative disease is commonly associated with inflammation, causing pain and accelerating degradation of the cartilage matrix.	28170076
Inflammation, Ocular surface disease	Altered Intercellular Communication	Rosacea-related cutaneous inflammation is a common cause of ocular surface disease.	28170535
vascular inflammations, Calcinosis, Chronic Kidney Diseases	Altered Intercellular Communication	Vascular inflammation and media calcification are already present in early stages of chronic kidney disease.	28171827
Calcinosis, vascular inflammations, Calcification of the aorta, Chronic Kidney Diseases	Altered Intercellular Communication	Thereby, aortic wall thickness and calcification score of aortic intima and of V. saphena were significantly higher in advanced CKD patients than in nonrenal control patients, whereas significant vascular inflammation and proosteogenic dedifferentiation of VSMC and calcification of the aortic media were already present in early CKD.	28171827
Inflammation, Calcinosis	Altered Intercellular Communication	Of note, calcium-phosphate product correlated well with markers of inflammation, but not with calcification itself.	28171827
Inflammation, Liver carcinoma, Liver Cirrhosis	Altered Intercellular Communication	Hepatocellular carcinoma usually develops in the setting of cirrhosis or chronic inflammation.	28173830
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	While the role of the gut microbiome in inflammation and colorectal cancers has received much recent attention, there are few data to support an association between the oral microbiome and head and neck squamous cell carcinomas.	28173873
Airway structure	Altered Intercellular Communication	Phthalate-induced oxidative stress and association with asthma-related airway inflammation in adolescents.	28174042
Inflammation	Altered Intercellular Communication	We hypothesized that biomarkers of inflammation predict the development and progression of DSPN in a population-based cohort.	28174259
Inflammation	Altered Intercellular Communication	The predictive value of systemic levels of eight biomarkers of inflammation was assessed for incident DSPN in 133 incident case subjects and 397 individuals without incident DSPN, and for DSPN progression in 57 patients with prevalent DSPN at both time points.	28174259
vascular inflammations	Altered Intercellular Communication	Systemic subclinical and vascular inflammation predicted both the onset and progression of DSPN over 6.5 years in an older general population.	28174259
Mycosis Fungoides, Lymphoma, T-Cell, Cutaneous, Inflammation	Altered Intercellular Communication	Cutaneous T-cell lymphomas (CTCL), especially mycosis fungoides, can be considered as a state of longstanding low-grade systemic inflammation.	28175924
Inflammation, Primary bone lymphoma	Altered Intercellular Communication	This case suggests that chronic inflammation induced by prolonged IUD insertion may contribute to the development of primary uterine lymphoma.	28176228
Inflammation	Altered Intercellular Communication	Downregulation of tricellulin causes increased permeability to macromolecules and subsequent microbial translocation contributes to systemic inflammation.	28176790
Inflammation	Altered Intercellular Communication	Interleukin (IL)-33 promotes T helper (Th)2 immunity and systemic inflammation.	28176939
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	C-reactive protein (CRP) is a systemic marker of inflammation that correlates with disease status in cystic fibrosis (CF).	28178305
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The liver-derived C-reactive protein (CRP) is a sensitive and systemic biomarker of inflammation, and has been associated with increased risk of developing type 2 diabetes in populations other than Chinese.	28178951
Inflammation	Altered Intercellular Communication	Background: Observational studies suggest an inverse association between whole-grain (WG) consumption and inflammation.	28179226
Inflammation, Asthma, Tumor necrosis	Altered Intercellular Communication	Our objective was to determine molecular phenotypes of asthma by analysing sputum cell transcriptomics from 104 moderate-to-severe asthmatic subjects and 16 nonasthmatic subjects.After filtering on the differentially expressed genes between eosinophil- and noneosinophil-associated sputum inflammation, we used unbiased hierarchical clustering on 508 differentially expressed genes and gene set variation analysis of specific gene sets.We defined three transcriptome-associated clusters (TACs): TAC1 (characterised by immune receptors IL33R, CCR3 and TSLPR), TAC2 (characterised by interferon-, tumour necrosis factor-a- and inflammasome-associated genes) and TAC3 (characterised by genes of metabolic pathways, ubiquitination and mitochondrial function).	28179442
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Background: Diet is known to influence systemic inflammation, a recognized risk factor for colorectal cancer (CRC).	28179489
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Background: During development of cardiovascular disease (CVD), interferon-g-mediated inflammation accelerates degradation of tryptophan into downstream metabolites.	28179491
Inflammation, Lung Injury, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Twist1 may shape the IPF phenotype and regulate inflammation in fibrotic lung injury.	28179498
Vasculitis, Takayasu Arteritis	Altered Intercellular Communication	18F-FDG PET reveals unique features of large vessel inflammation in patients with Takayasu's arteritis.	28180963
Inflammation	Altered Intercellular Communication	PET/CT may be useful in the assessment of local inflammatory and vascular remodelling events independent of systemic inflammation during follow-up, even in lesions in which the arterial wall is <4 mm.	28180963
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We conclude that the transition of fibroblast to myofibroblasts via TGF-b pathway is a key linker between inflammation and fibrosis in LFH mechanism.	28180980
Inflammation	Altered Intercellular Communication	This report is apparently the first showing that adherence to MedDiet is associated with the methylation of the reported genes related to inflammation with a potential regulatory impact.	28181167
Inflammation, Ischemic stroke	Altered Intercellular Communication	Increasing evidences have demonstrated that inflammation is involved in the mechanisms of acute ischemic stroke (AIS).	28181171
Inflammation	Altered Intercellular Communication	Systemic inflammation may contribute to disability independently of clinical vascular events.	28181636
Lower Urinary Tract Symptoms, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	Chronic prostatic inflammation is implicated in the pathogenesis of benign prostatic hyperplasia (BPH)-associated lower urinary tract symptoms (LUTS).	28181681
prostatitis	Altered Intercellular Communication	Previous studies evaluated the degree of chronic prostatic inflammation based on histological scores, which may contain subjective factors.	28181681
Inflammation, Gastrointestinal inflammation	Altered Intercellular Communication	We previously demonstrated that the number of high endothelial venule (HEV)-like vessels correlates positively with the magnitude of inflammation in chronic inflammatory gastrointestinal diseases.	28181681
Inflammation, Lower Urinary Tract Symptoms, prostatitis	Altered Intercellular Communication	Here, we evaluated the degree of BPH-associated chronic prostate inflammation based on appearance of HEV-like vessels and determined whether the extent of inflammation correlated with LUTS severity, as evaluated by a urodynamic study.	28181681
Lower Urinary Tract Symptoms, prostatitis	Altered Intercellular Communication	We also determined whether the magnitude of chronic prostatic inflammation, as assessed by HEV-like vessel number, correlated with the degree of LUTS.	28181681
Lower Urinary Tract Symptoms, prostatitis	Altered Intercellular Communication	The number of HEV-like vessels positively correlated not only with the magnitude of chronic prostatic inflammation but also with the degree of LUTS, particularly with symptoms associated with voiding function, which was measured objectively in a pressure flow study.	28181681
Dysfunctional voiding of urine, prostatitis	Altered Intercellular Communication	Chronic prostate inflammation may promote BPH and resulting voiding dysfunction.	28181681
prostatitis	Altered Intercellular Communication	Assessment of the number of HEV-like vessels could be a surrogate for identifying the degree of chronic prostatic inflammation.	28181681
Trachoma , Inflammation	Altered Intercellular Communication	We fit the four different mechanistic models of trachoma transmission to cross-sectional age-specific Polymerase Chain Reaction (PCR) and Trachomatous inflammation, follicular (TF) prevalence data.	28182664
Inflammation, ETV3 wt Allele, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Low-grade inflammation is associated with obesity and the metabolic syndrome (MetS).	28182820
Airway structure, Refractory anemias	Altered Intercellular Communication	The association of anti-CCP with elevated cell counts and NET levels in FDRs supports a hypothesis that local airway inflammation and NET formation may drive anti-CCP production in the lung and may promote the early stages of RA development.	28182854
Inflammation, Bursitis	Altered Intercellular Communication	LCA revealed four groups: (1) bursitis with limited inflammation elsewhere (n = 1280), (2) bursitis with extensive inflammation (n = 595), (3) rotator cuff tears (n = 558) and (4) limited pathology (n = 567).	28183338
Rheumatoid Arthritis, Endothelium, Inflammation	Altered Intercellular Communication	Endothelial injury in rheumatoid arthritis: a crosstalk between dimethylarginines and systemic inflammation.	28183353
Arterial Stiffness, Inflammation	Altered Intercellular Communication	Significant interactions with inflammation were detected in the associations between ACh and both SDMA (p = 0.014) and ADMA:SDMA ratio (p = 0.027), as well as between SNP and SDMA (p = 0.042) and between arterial stiffness and ADMA:SDMA (p = 0.036), with the associations being stronger in the patients with high inflammatory markers in each case.	28183353
Refractory anemias, Inflammation, Endothelium, Disease remission	Altered Intercellular Communication	Besides their emerging role as markers of endothelial dysfunction SDMA and ADMA may promote endothelial injury in RA as mediators of the adverse effects of systemic inflammation on micro- and macrovasculature respectively in patients with active disease.	28183353
Inflammation	Altered Intercellular Communication	Nevertheless, dietary saturated fatty acids increased LCn-3PUFA in plasma and tissue lipids compared with n-6PUFA, potentially reducing other cardiovascular risk factors such as inflammation and clotting tendency.	28183443
Inflammatory disease of mucous membrane, Osteopenia	Altered Intercellular Communication	All patients reported with mucosa inflammation and bone loss and/or implant failures to the first annual examination were identified.	28185409
Inflammation	Altered Intercellular Communication	Highest risk for early inflammation was observed for patients at an age of 50-55 years at surgery (P < .05).	28185409
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Communicable Diseases	Altered Intercellular Communication	This study investigated the importance of neutrophil/lymphocyte ratio (NLR) and other new inflammatory markers including CD64 expression in patients with chronic obstructive pulmonary disease (COPD) for identifying the severity of inflammation and recognition of acute exacerbation and infection.	28185443
ARCN1 gene, Inflammation	Altered Intercellular Communication	Elevated NLR can be used as a marker similar to CRP, and RDW, in the determination of increased inflammation in acutely exacerbated COPD.	28185443
Pneumonitis, CTCAE, Inflammation	Altered Intercellular Communication	Fluorodeoxyglucose PET/CT scanning can reveal inflammation secondary to pneumonitis but is not sufficiently specific for diagnosis.	28185527
Disorder of the optic nerve, Orbital Pseudotumor	Altered Intercellular Communication	The patients had a Mourits' score greater than three after treatment with corticosteroids and/or a severe NOSPECS score and/or orbital inflammation resistant to maximal treatment with intravenous injections of methylprednisolone and an optic neuropathy.	28185649
Inflammation, Hemorrhage, Traumatic injury	Altered Intercellular Communication	A number of pathophysiological descriptions involving aberrant angiogenic responses following trauma, hemorrhage, or inflammation have been proposed, although the exact etiology of these lesions remains to be elucidated.	28186446
Inflammation, Malnutrition	Altered Intercellular Communication	In models adjusted for iron dose, malnutrition and inflammation, mean ferritin levels increased over time in the overall cohort and across the three lower baseline ferritin strata.	28186572
Inflammation, Obesity	Altered Intercellular Communication	A direct link between development of insulin resistance and the presence of chronic inflammation, in case of obesity exists, with cytokines playing an important role in glucose metabolism.	28186649
Inflammation	Altered Intercellular Communication	However, local inflammation may result and can contribute to worsening of clinical status in these patients.	28186686
Osteosclerosis, Fracture, Inflammation, Osteolysis	Altered Intercellular Communication	We investigated the CT and dental panoramic radiograph (DPR) images for osteolysis, osteosclerosis, sequestration, periosteal reaction, pathological fracture and spread of soft tissue inflammation around the jaws.	28186845
Osteosclerosis, Inflammation, Osteolysis	Altered Intercellular Communication	Osteolysis, osteosclerosis, sequestration and spread of soft tissue inflammation around the jaws were common radiological features in both BRONJ and ORN.	28186845
Osteosclerosis, Inflammation, Osteolysis	Altered Intercellular Communication	Osteolysis and spreading of soft tissue inflammation around the jaws were predominant in ORN, and by contrast osteosclerosis was predominant in BRONJ.	28186845
Inflammation, Osteolysis	Altered Intercellular Communication	Image findings of BRONJ were characterized as a severe sclerotic change combined with osteolysis, sequestration, periosteal reaction and spread of soft tissue inflammation around the jaws.	28186845
Inflammation, Prosopagnosia	Altered Intercellular Communication	Tumoral Presentation of Homonymous Hemianopia and Prosopagnosia in Cerebral Amyloid Angiopathy-Related Inflammation.	28187081
Cerebral Amyloid Angiopathy, Inflammation	Altered Intercellular Communication	Found to have cerebral amyloid angiopathy-related inflammation proven by brain biopsy, she was treated successfully with immunosuppression.	28187081
Refractory anemias, Inflammation	Altered Intercellular Communication	Concentrations of small LDL (LDL-P) and HDL (HDL-P) particles are also reduced with increased inflammation and disease activity in RA patients.	28187765
Inflammation	Altered Intercellular Communication	Here we sought to identify which measure(s) of inflammation, disease activity and cardiometabolic risk contribute most to the RA-associated lipoprotein profile.	28187765
Refractory anemias, Pain Distress Question, Inflammation	Altered Intercellular Communication	Among RA patients, relationships were determined for lipoprotein parameters with measures of disease activity, disability, pain, inflammation, body composition, insulin sensitivity and exercise.	28187765
Endothelial dysfunction	Altered Intercellular Communication	Inflammation-induced caveolin-1 and BMPRII depletion promotes endothelial dysfunction and TGF-b-driven pulmonary vascular remodeling.	28188225
Granulomatous inflammation	Altered Intercellular Communication	* Pathological diagnosis of granulomatous inflammation is a robust indicator for 'true-negatives'.	28188426
Ascites	Altered Intercellular Communication	The glycome of ascites shows typical features of inflammatory conditions, what was also found in the serum of patients suffering from EOC when compared to healthy serum.	28188862
Inflammation, Milk, Human	Altered Intercellular Communication	Based on the role of calprotectin in inflammation, its higher levels in exclusively breastfed infants is contrary to breast milk benefits and may be a sign of enhanced mucosal immune maturity in them.	28188944
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The role of inflammation in the pathogenesis of osteoarthritis is being given major interest, and inflammation is closely linked with vascularization.	28189197
Inflammation, Coronary Artery Disease, Atherosclerosis, Coronary Thrombosis	Altered Intercellular Communication	Inflammation plays an important role in atherosclerosis formation, coronary artery disease progression, acute coronary thrombosis and occlusion.	28189264
Vascular System Injuries	Altered Intercellular Communication	Chemokines are inflammatory mediators disposing several bio-functions, as leukocyte migration towards inflammatory signals and vascular injuries.	28189264
Lichen Planus	Altered Intercellular Communication	Increased melatonin in oral mucosal tissue of oral lichen planus (OLP) patients: A possible link between melatonin and its role in oral mucosal inflammation.	28189880
Inflammation	Altered Intercellular Communication	Increased levels of AANAT, melatonin, and MT1 in the inflamed oral mucosal tissue of OLP patients imply that chronic inflammation may induce the local biosynthesis of melatonin via AANAT, and may enhance the action of melatonin via MT1.	28189880
Inflammation, Blood Vessel, Antihypertensive Agents	Altered Intercellular Communication	We investigated whether Southern Italy resistant hypertensives presented an association between the presence of I and/or D alleles and early vascular damage, inflammation, and insulin resistance.	28190172
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	DD genotype appeared to be associated with AS and HOMA index, but not with inflammation, independently from blood pressure values and the presence of other MetS factors, confirming D allele as an independent risk marker.	28190172
ARCN1 gene, Inflammation	Altered Intercellular Communication	Overall, chronic inflammation may expand sub-populations of T cells expressing CTLA-4 in COPD patients and therefore impair T-cell function.	28190271
Hyperpyrexia	Altered Intercellular Communication	Glutamate is an excitatory neurotransmitter that is utilized by the organum vasculosum laminae terminalis through the neuronal excitatory system and causes an increase in body temperature which can lead to hyperpyrexia.	28190402
Inflammation, Cardiovascular morbidity	Altered Intercellular Communication	Systemic inflammation biomarkers have been associated with risk of cardiovascular morbidity and mortality.	28190687
Inflammation, Primary malignant neoplasm, Allergy - Charge Type Reason, Autoimmune Diseases, Immune System Diseases	Altered Intercellular Communication	It is known that PIDs can also predispose to cancer and immune diseases, including allergy, autoimmunity, and inflammation.	28192146
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	We aimed at determining the incidence of autoimmunity and inflammation in patients with PIDs.	28192146
MTA2 gene, Inflammation, Autoimmune Diseases	Altered Intercellular Communication	We have retrospectively screened 2183 consecutive cases of PID in the Centre de Reference Deficits Immunitaires Hereditaires registry (CEREDIH; the French national PID registry) for the occurrence of autoimmunity and inflammation.	28192146
Inflammation, Primary Biliary Cholangitis	Altered Intercellular Communication	In this study, four microRNAs were identified as being decreased in PBC patients, leading to activation of T cell receptor signalling pathways, involved in inflammation.	28192189
Craniocerebral Trauma, Hyperlipidemia, Primary malignant neoplasm, Malnutrition, Atrial Fibrillation by ECG Finding, Presenile dementia, Autoimmune Diseases, Diabetes Mellitus, Cerebrovascular accident, Congestive heart failure, Chronic Obstructive Airway Disease, Hepatobiliary Disorder, Coronary Artery Disease, Depression, CTCAE, Acute and chronic inflammation, Hypertension, CTCAE	Altered Intercellular Communication	A 1.88-fold increased risk of dementia (95% confidence interval, 1.76-2.01) was observed after adjustment for age, sex, and several comorbidities (diabetes, hypertension, hyperlipidemia, head injury, depression, stroke, chronic obstructive pulmonary disease, coronary artery disease, congestive heart failure, atrial fibrillation, cancer, liver disease, chronic infection/inflammation, autoimmune disease, malnutrition).	28192452
Cartilage destruction, Inflammation, Arthritis	Altered Intercellular Communication	In vivo, A77 1726 reduced the clinical arthritis severity of histological inflammation and cartilage destruction.	28193225
Arthritis, Autoimmune arthritis	Altered Intercellular Communication	The inhibitory effects of A77 1726 on joint inflammation and oxidative stress in autoimmune arthritis may be associated with HO-1 induction in CD4+ T cells.	28193225
Inflammation, Bipolar Disorder, Breast Carcinoma, Fatigue	Altered Intercellular Communication	Depressive symptoms and inflammation are independent risk factors of fatigue in breast cancer survivors.	28193310
Inflammation, Bipolar Disorder, Dyssomnias, Fatigue	Altered Intercellular Communication	A post-hoc mediation model using PROCESS SPSS was conducted to examine the association among depressive symptoms, sleep problems, stress, inflammation and fatigue.	28193310
Primary malignant neoplasm	Altered Intercellular Communication	MicroRNA 301A Promotes Intestinal Inflammation and Colitis-Associated Cancer Development by Inhibiting BTG1.	28193514
Primary malignant neoplasm	Altered Intercellular Communication	Transforming growth factor (TGF)-b-activated kinase 1 (TAK1) is one of the major regulators of inflammation-induced cancer cell growth and progression.	28194669
Inflammation, AT-Hook Motifs, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a pivotal role in the initiation and progression of atherosclerosis (ATH).	28194905
Neoplasms	Altered Intercellular Communication	High CR expression was associated with tumors of high grade (P < 0.0001), high locoregional recurrence (P = 0.005), hormonal receptors negative, and high Ki-67 indices.	28195084
Inflammation, neuropeptide hormone activity	Altered Intercellular Communication	Our main findings were: (i) Compared to controls, patients with HF had significantly increased levels of factor D and TCC, and decreased levels of properdin, particularly patients with advanced clinical disorder (i.e., NYHA functional class IV), (ii) Levels of factor D and properdin in HF patients were correlated with measures of systemic inflammation (i.e., C-reactive protein), neurohormonal deterioration (i.e., Nt-proBNP), cardiac function, and deteriorated diastolic function, (iii) Low levels of factor H and properdin were associated with adverse outcome in univariate analysis and for factor H, this was also seen in an adjusted model.	28195242
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Analysis of the histologic features showed that the concomitant presence of inflammation, nerve bundles, and fibrosis (often mild) is prevalent in VD.	28195255
Inflammation, Fibrosis Assessment, Federated States of Micronesia	Altered Intercellular Communication	Fibrosis is highly frequent and often moderate/severe in FM and it is rarely associated to inflammation and nerve bundles.	28195255
vascular inflammations	Altered Intercellular Communication	Low salivary resolvin D1 to leukotriene B4 ratio predicts carotid intima media thickness: A novel biomarker of non-resolving vascular inflammation.	28195518
vascular inflammations	Altered Intercellular Communication	Background Different lipid mediators may have opposing effects on vascular inflammation.	28195518
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Conclusions The ratio between the proresolving and proinflammatory salivary lipid mediators RvD1 and LTB4 may serve as a biomarker of non-resolving inflammation and its relation to intima media thickness in cardiovascular disease.	28195518
Lymphoma, Chronic inflammation, Neoplasms	Altered Intercellular Communication	Fibrin-associated EBV-positive Large B-Cell Lymphoma: An Indolent Neoplasm With Features Distinct From Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation.	28195879
Inflammation	Altered Intercellular Communication	Incidental cases of localized fibrin-associated Epstein-Barr virus (EBV)+ large B-cell proliferations have been described at unusual anatomic sites and have been included in the category of diffuse large B-cell lymphoma associated with chronic inflammation (DLBCL-CI) in the WHO Classification.	28195879
AURKAIP1 gene, Carcinogenesis	Altered Intercellular Communication	AIP's inflammatory condition may be related to carcinogenesis.	28196014
Inflammation, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	BACKGROUND Myocarditis, defined as inflammation of myocardial tissue of the heart, is an uncommon cardiac presentation and is due to a variety of causes.	28196967
Inflammation, Liver carcinoma, FAM126A gene	Altered Intercellular Communication	The Glasgow Prognostic Score (GPS), a simple assessment of systemic inflammation status, could be useful to predict the prognosis of hepatocellular carcinoma (HCC) patients after hepatectomy.	28197709
Non-necrotizing granulomatous inflammation	Altered Intercellular Communication	Lymph node biopsies revealed non-caseating granulomatous inflammation.	28199763
Inflammation, HIV	Altered Intercellular Communication	Genital inflammation is a key determinant of human immunodeficiency virus (HIV) transmission, and may increase HIV-susceptible target cells and alter epithelial integrity.	28201724
Inflammation	Altered Intercellular Communication	Chronic inflammation of the peritoneum causes peritoneal injury in patients on peritoneal dialysis.	28201944
Inflammation	Altered Intercellular Communication	Intercellular adhesion molecule-1 and its circulating form, soluble intercellular adhesion molecule-1, play pivotal roles in inflammation.	28201944
Inflammation, Cholangitis	Altered Intercellular Communication	The pathological report showed severe acute and chronic inflammation of the bile duct with morphology and immunohistochemistry suggestive of IgG4-related sclerosing cholangitis.	28202062
Inflammation, Asthma, Deep thrombophlebitis	Altered Intercellular Communication	Asthma was associated with an increased risk of PE, DVT and combined PE and DVT.Thus, the inflammation conferred by asthma seems to have systemic (and not just local) prothrombotic effects with increased risk of both DVT and PE.	28202551
Inflammation, Sleep Apnea, Obstructive, Metabolic Syndrome X	Altered Intercellular Communication	Concurrent presence of inflammation and obstructive sleep apnea exacerbates the risk of metabolic syndrome: A KoGES 6-year follow-up study.	28207497
Inflammation, Sleep Apnea, Obstructive, Osage language	Altered Intercellular Communication	Obstructive sleep apnea (OSA) leads to multiple end-organ morbidities that are mediated by the cumulative burden of oxidative stress and inflammation.	28207497
Inflammation, Osage language, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Both OSA and inflammation play key roles in increased risk of cardiovascular disease (CVD).	28207497
Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Osage language	Altered Intercellular Communication	Thus, we hypothesized that the combination of inflammation and OSA could accelerate the development of metabolic syndrome (MetS) in a large cohort study.A total of 1835 participants were randomly selected from the ongoing Korean Genome and Epidemiology Study for the years between 2007 and 2015.	28207497
Inflammation, ETV3 wt Allele, Osage language	Altered Intercellular Communication	The incidence of MetS among the 4 groups stratified by OSA and inflammation status at the 6-year follow-up was 11.8%, 19.9%, 25.8%, and 36.0% (HsCRP[-]/OSA[-] vs HsCRP[+]/OSA[-] vs HsCRP[-]/OSA[+] vs HsCRP[+]/OSA[+], P < 0.01).	28207497
Inflammation, ETV3 wt Allele, Osage language	Altered Intercellular Communication	Additional research is needed to help further define the significance of the combined effect of OSA and subclinical inflammation on the development of MetS in the context of reduction of CVD risk.	28207497
Inflammation, Spinal Cord Injuries, Traumatic, Cardiac Arrest, Communicable Diseases, Cerebrovascular accident, Status Epilepticus, Hydrocephalus	Altered Intercellular Communication	Children 7 days to 17 years old admitted to the ICU with new traumatic brain injury, stroke, cardiac arrest, CNS infection or inflammation, status epilepticus, spinal cord injury, hydrocephalus, or brain mass.	28207570
Cardiac Arrest, Inflammation	Altered Intercellular Communication	The most common neurologic insult was infection/inflammation in South America, Asia, and the single African site but cardiac arrest in the remaining regions.	28207570
Inflammation, Overweight, Chronic disease	Altered Intercellular Communication	This study examined the effects of an encapsulated fruit and vegetable (F&V) juice concentrate on systemic inflammation and other risk factors for chronic disease in overweight and obese adults.	28208713
Inflammation	Altered Intercellular Communication	Therefore, F&V juice concentrate improves the metabolic profile, by reducing systemic inflammation and blood lipid profiles and, thus, may be useful in reducing the risk of obesity-induced chronic disease.	28208713
Inflammation, Primary malignant neoplasm, Cachexia, Neoplasms	Altered Intercellular Communication	A high neutrophil/lymphocyte ratio (NLR) at baseline and at follow-up is associated with shorter survival in cancer patients and may be a surrogate for ongoing inflammation, implicated in cancer cachexia and tumor progression.	28209123
Non-Small Cell Lung Carcinoma, Cachexia, Neoplasms	Altered Intercellular Communication	In addition to having prognostic significance, these observations suggest that studying molecular mediators of cachexia/inflammation and their relationships to tumor progression may identify new therapeutic targets in the large subset of NSCLC patients who have cancer cachexia.	28209123
Inflammation, Lip and Oral Cavity Carcinoma	Altered Intercellular Communication	C-reactive protein (CRP) is an early marker for inflammation, and a relationship between serum CRP levels and survival in oral cancer has been demonstrated previously.	28209200
Hypernatremia, Inflammation	Altered Intercellular Communication	In hemodialysis patients extracellular fluid overload is a predictor of all-cause and cardiovascular mortality, and a relation with inflammation has been reported in previous studies.	28209335
Hypernatremia, Inflammation, Cessation of life	Altered Intercellular Communication	The concurrent presence of fluid overload and inflammation was associated with the highest risk of death.	28209335
Hypernatremia, Inflammation	Altered Intercellular Communication	Thus, while pre-dialysis fluid overload was associated with inflammation, even in the absence of inflammation, fluid overload remained a significant risk factor for short-term mortality, even following improvement of fluid status.	28209335
Airway structure, Asthma	Altered Intercellular Communication	Blood eosinophil count is a marker of eosinophilic airway inflammation and disease severity in asthma.	28209625
Communicable Diseases, Inflammation, Traumatic injury, Neoplasms	Altered Intercellular Communication	Trauma, infection, inflammation, neoplasia, and mechanical obstruction are secondary one.	28210015
Inflammation, Periodontitis, Bacterial Infections	Altered Intercellular Communication	Due to its potential to influence systemic inflammation and oxidative stress, and to predispose to bacterial infections, sleep duration could potentially be a risk factor for periodontitis.	28211083
Inflammation	Altered Intercellular Communication	In particular, increased levels of inflammation markers as well as DNA damage are observed.	28211642
Inflammation	Altered Intercellular Communication	Pharmacological intervention reverses the strain-induced damage by shifting gene expression profile away from inflammation.	28211642
Loss of myelin, Inflammation, Blood Vessel	Altered Intercellular Communication	Deep frontal white matter showed increased gliosis in HIV+ subjects vs. HIV- controls (p = 0.09), but no significant differences in myelin loss, blood vessel thickening, or inflammation.	28212619
Inflammation, Fatty degeneration	Altered Intercellular Communication	Liver showed more severe fibrosis/cirrhosis (p = 0.02) and less steatosis (p = 0.03) in HIV+ subjects, but no significant differences in inflammation, blood vessel thickness, or pigment deposition.	28212619
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Inflammation is a key process underlying the clinical course of coronary artery disease (CAD).	28212870
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Osteoarthritis (OA) is a degenerative joint disease characterized by cartilage degradation and inflammation.	28213268
Fragile X Syndrome	Altered Intercellular Communication	The behavioral and anatomical deficits seen in fragile X syndrome (FXS) are widely believed to result from imbalances in the relative strengths of excitatory and inhibitory neurotransmission.	28213518
Deficit, Fragile X Syndrome	Altered Intercellular Communication	Significantly, this deficit contributes to the pathophysiology of FXS as the GABABR agonist (R)-baclofen rescued the imbalances between excitatory and inhibitory neurotransmission evident in Fmr1-KO mice.	28213518
Inflammation, Demyelination, MS gene, Pathology	Altered Intercellular Communication	The presence of inflammation and demyelination in a central nervous system (CNS) biopsy points towards a limited, yet heterogeneous group of pathologies, of which multiple sclerosis (MS) represents one of the principal considerations.	28213912
Inflammation, Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Our data indicate that in the presence of extensive inflammation and incomplete, inhomogeneous demyelination, the neuropathologist should refrain from primarily considering autoimmune inflammatory demyelination and, even in the absence of lymphoma cells, instigate close clinical follow-up of the patient to detect recurrent lymphoma.	28213912
Vasculitis, Heart failure	Altered Intercellular Communication	Comorbidity-driven microvascular inflammation is postulated to play a key role in heart failure with preserved ejection fraction (HFpEF) pathophysiology, but data on how sST2 relates to clinical characteristics or inflammatory conditions or biomarkers in HFpEF are limited.	28214792
Inflammation, Fibrosis Assessment, Myocardial Infarction	Altered Intercellular Communication	Clinical characteristics; cardiac structure and function; exercise performance; and biomarkers of neurohumoral activation, systemic inflammation and fibrosis, and myocardial necrosis were assessed in relation to sST2 levels.	28214792
Inflammation, Atrial Fibrillation by ECG Finding, Fibrosis Assessment, Myocardial Infarction, Diabetes Mellitus, Tissue Congestion, physiopathological, Impaired exercise tolerance, Renal Insufficiency	Altered Intercellular Communication	Among HFpEF patients, higher sST2 levels were associated with the presence of diabetes mellitus; atrial fibrillation; renal dysfunction; right ventricular pressure overload and dysfunction; systemic congestion; exercise intolerance; and biomarkers of systemic inflammation and fibrosis, neurohumoral activation, and myocardial necrosis (P<0.05 for all).	28214792
Inflammation	Altered Intercellular Communication	These data suggest that ST2 may be a marker of systemic inflammation in HFpEF and potentially of extracardiac origin.	28214792
Vasculitis, Heart failure	Altered Intercellular Communication	Comorbidity-driven microvascular inflammation is postulated to play a key role in heart failure with preserved ejection fraction (HFpEF) pathophysiology, but data on how sST2 relates to clinical characteristics or inflammatory conditions or biomarkers in HFpEF are limited.	28214792
Inflammation, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Liver damage, Obesity	Altered Intercellular Communication	The incidence of nonalcoholic fatty liver disease (NAFLD), ranging from mild steatosis to hepatocellular injury and inflammation, increases with the rise of obesity.	28214827
Cessation of life, Inflammation, Fever, CTCAE	Altered Intercellular Communication	Eryptosis, the suicidal erythrocyte death characterized by cell shrinkage and phosphatidylserine-translocation, is triggered by fever and inflammation.	28214863
Communicable Diseases, Inflammation, Collagen Diseases	Altered Intercellular Communication	Urinary free light chains may help to identify infection in patients with elevated systemic inflammation due to rheumatic disease.	28214923
Communicable Diseases, Inflammation, Rheumatism	Altered Intercellular Communication	The risk of infection in patients with rheumatic diseases is elevated, but a clear marker to differentiate the cause of the systemic inflammation is missing.	28214923
Communicable Diseases, Inflammation, Collagen Diseases	Altered Intercellular Communication	Of the 382 patients with rheumatic disease, 172 (45%) displayed no systemic inflammation, 162 (42%) had inflammation due to the underlying disease activity, and 48 (13%) had inflammation due to a confirmed infection.	28214923
Communicable Diseases, Inflammation, Rheumatism, Collagen Diseases	Altered Intercellular Communication	Urinary FLC concentrations were much higher in patients with rheumatic diseases and infection (k 68.8 +- 81.8 mg/L, l 31.4 +- 53.5 mg/L) compared to those with inflammation due to rheumatic disease activity (k 22.7 +- 26.3 mg/L, l 8.1 +- 9.1 mg/L, k p < 0.001, l p = 0.004).	28214923
Communicable Diseases, Inflammation, Collagen Diseases	Altered Intercellular Communication	FLCs may be useful for distinguishing inflammation due to rheumatic disease activity from that due to the additional presence of infection.	28214923
Inflammatory Bowel Diseases, Inflammation, MS gene	Altered Intercellular Communication	Fibronectin connecting segment-1 (FNCS1), an alternatively spliced fibronectin variant expressed by microvascular endothelial cells at sites of inflammation in vitro and in situ, is a counterligand for leukocyte a4 integrin (also known as CD49d) implicated in pathogenic leukocyte trafficking in multiple sclerosis and inflammatory bowel disease.	28215575
Inflammation	Altered Intercellular Communication	Additionally, extensor tendon inflammation (ETI) (0-3) was scored.	28216312
Airway structure	Altered Intercellular Communication	Extracellular eosinophilic traps in association with Staphylococcus aureus at the site of epithelial barrier defects in patients with severe airway inflammation.	28216437
Inflammation, Nasal Polyps, Chronic sinusitis	Altered Intercellular Communication	Chronic rhinosinusitis with nasal polyps is characterized by TH2-biased eosinophilic inflammation.	28216437
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	These results support the role of complement-dependent inflammation in the pathophysiology of cardiovascular disease.	28216633
Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Fatty Liver Disease	Altered Intercellular Communication	Serum LBP concentration was significantly increased in nonalcoholic steatohepatitis (NASH) patients as compared with nonalcoholic fatty liver (NAFL) subjects and was correlated with steatosis (r = 0.38, P < 0.0001) and ballooning scores (r = 0.23, P = 0.01), but not with the severity of lobular inflammation or fibrosis.	28216979
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	LBP/EndoCab IgG were not correlated with lobular inflammation or fibrosis.	28216979
Myocarditis	Altered Intercellular Communication	The mechanisms underlying the disease process have not been precisely identified, but recent evidence has suggested that the activation of myocardial inflammation is involved in the deterioration associated with the condition.	28217949
Inflammation, Carcinogenesis	Altered Intercellular Communication	Inflammation plays a major role in colon carcinogenesis.	28218420
Inflammation, Carcinogenesis	Altered Intercellular Communication	Endogenously produced specialized proresolving lipid mediators (SPMs) play a central role in inflammation and tissue homeostasis, and have been implicated in carcinogenesis.	28218420
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Defensive coping (DefS), oxidative stress, inflammation, and related amino acids (phenylalanine [Phe] and tyrosine [Tyr]) have been implicated in cardiovascular disease.	28218795
Inflammation, Obesity, Abdominal, Alcohol abuse	Altered Intercellular Communication	African men had poorer health than Caucasian men, including higher alcohol abuse, elevated BP, abdominal obesity, physical inactivity, and elevated inflammation.	28218795
Inflammation, Abnormality of the vasculature	Altered Intercellular Communication	African males presented with elevated Phe and Phe/Tyr ratio, catecholamine precursors, worsening during DefS-possibly driven by inflammation and BP contributing to structural vascular abnormalities.	28218795
Inflammation, Cervical Intraepithelial Neoplasia	Altered Intercellular Communication	In conclusion, ATIII appears to attenuate CIN through inhibiting inflammation, oxidative stress, apoptosis and improving renal blood flow.	28219627
Inflammation, Pruritus	Altered Intercellular Communication	Substance P (SP) is linked to itch and inflammation through activation of receptors on mast cells and sensory neurons.	28219706
Inflammation, Pruritus	Altered Intercellular Communication	Because Mrgprs mediate some aspects of inflammation that had been considered mediated by neurokinin-1 receptor (NK-1R), we sought to determine whether itch induced by SP can also be mediated by Mrgprs.	28219706
Inflammation, Atherosclerosis	Altered Intercellular Communication	DKK3 expression in macrophages is involved in the pathogenesis of atherosclerosis through modulation of inflammation and inactivation of the Wnt/b-catenin pathway.	28219919
Inflammation, Tissue Adhesions	Altered Intercellular Communication	In certain situations visualization of the Callot triangle can become difficult due to inflammation, adhesions, and sclerosing of the anatomy.	28220035
Neuromuscular Junction Diseases, Myasthenic Syndromes, Congenital, CD2AP gene	Altered Intercellular Communication	Congenital myasthenic syndromes (CMS) are a heterogeneous group of diseases of the neuromuscular junction caused by compromised synaptic transmission.	28221305
Inflammation	Altered Intercellular Communication	There was no inflammation or ciliary body detachment.	28221333
Inflammation, Pain Distress Question	Altered Intercellular Communication	The infrapatellar fat pad (IPFP) represents intra-articular adipose tissue that may contribute to intra-articular inflammation and pain by secretion of proinflammatory cytokines.	28222422
Inflammation, MS gene	Altered Intercellular Communication	Increased cortical lesion load and intrathecal inflammation is associated with oligoclonal bands in multiple sclerosis patients: a combined CSF and MRI study.	28222766
Cerebral cortex, Inflammation, MS gene	Altered Intercellular Communication	Although IgG oligoclonal bands (OCBs) in the cerebrospinal fluid (CSF) are a frequent phenomenon in multiple sclerosis (MS) patients, their relationship with grey matter lesions, intrathecal/meningeal inflammation and clinical evolution has not been clarified yet.	28222766
Inflammation, Pancreatic Ductal Adenocarcinoma	Altered Intercellular Communication	There is strong evidence linking inflammation and the development of pancreatic ductal adenocarcinoma.	28222855
Inflammation	Altered Intercellular Communication	Performance of subjective global assessment and malnutrition inflammation score for monitoring the nutritional status of older adults on hemodialysis.	28222963
Inflammation, Reperfusion Injury	Altered Intercellular Communication	Monocyte chemotactic protein-1 (MCP-1; chemokine C-C ligand-2 [CCL-2]) is upregulated in ischemia-reperfusion injury and is a promising biomarker of inflammation in cardiac operations.	28223055
Inflammation, Fibrosis Assessment, Pneumonia, Interstitial, Granuloma	Altered Intercellular Communication	Patients with a fibrotic nonspecific interstitial pneumonia (f-NSIP) pattern, bronchiolocentric fibrosis (BF) pattern, or usual interstitial pneumonia (UIP) pattern had significantly worse transplant-free survival than did those with a cellular NSIP (c-NSIP) pattern or peribronchiolar inflammation with poorly formed granulomas (PI-PFG) pattern.	28223152
Inflammation, Adult Glioblastoma	Altered Intercellular Communication	Preoperative inflammation markers and IDH mutation status predict glioblastoma patient survival.	28223536
Inflammation, Neoplasms	Altered Intercellular Communication	Recent studies suggest that inflammation response biomarkers are prognostic indicators of solid tumor outcomes.	28223536
Epithelial ovarian cancer	Altered Intercellular Communication	Several parameters of preoperative complete blood count (CBC) and inflammation-associated blood cell markers derived from them have been reported to correlate with prognosis in patients with epithelial ovarian cancer (EOC), but their prognostic importance and optimal cutoffs are still needed be elucidated.	28223716
Inflammation, Fibrosis Assessment, Liver Stiffness	Altered Intercellular Communication	Liver stiffness (LS) with MRE was calculated by a radiologist, and inflammation grade and fibrosis stage in liver biopsy was assessed by a pathologist in a blinded fashion.	28223730
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	There were no significant differences in distribution of fibrosis stage and inflammation grade between treated and untreated patient groups.	28223730
Inflammation, Acquired Immunodeficiency Syndrome, Frailty	Altered Intercellular Communication	Frailty and Circulating Markers of Inflammation in HIV+ and HIV- Men in the Multicenter AIDS Cohort Study.	28225718
Inflammation, Frailty	Altered Intercellular Communication	Frailty is associated with immune activation and inflammation in the elderly general population, but whether this is true in the younger HIV-infected (HIV+) population is not known.	28225718
Inflammation, Interferon-Related DNA Damage Resistance Gene Signature, Inflammatory disorder	Altered Intercellular Communication	Pentraxin 3 is proposed to be a marker of inflammation and cardiovascular risk, but its role in inflammatory rheumatic diseases (IRDs) is still uncertain.	28225768
Interferon-Related DNA Damage Resistance Gene Signature, Inflammation	Altered Intercellular Communication	Therefore, we wanted to examine if anti-rheumatic treatment reduced serum PTX3 (s-PTX3) levels in IRDs, and if s-PTX3 levels were related to other markers of inflammation and to endothelial function (EF).	28225768
Inflammation	Altered Intercellular Communication	Thus, s-PTX3 might reflect a persisting immune process, even a causal factor of inflammation, not inhibited by the standard anti-rheumatic treatment.	28225768
Inflammation, Atrial Fibrillation	Altered Intercellular Communication	A relation between inflammation and AF has been suggested by findings of increased inflammatory markers in AF patients.	28225836
Mitral Valve Insufficiency, Inflammation, Hypertension, CTCAE, Diabetes Mellitus	Altered Intercellular Communication	Immune cell infiltration of LA was related to the rhythm, but not to age, body size, LA size, mitral regurgitation grade, type of surgery, systemic markers of inflammation or presence of diabetes or hypertension.	28225836
Inflammation	Altered Intercellular Communication	Knowledge of these variants in T2DM might contribute to a better understanding of the role of inflammation in the etiology and progression of this disease.	28225860
Inflammatory Bowel Diseases, Crohn Disease, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are characterized by chronic inflammation of the intestine that can reduce the absorption of nutrients such as vitamin D and calcium.	28225873
Communicable Diseases, Inflammation	Altered Intercellular Communication	Due to inflammation, it may be difficult to diagnose infection when it occurs, but measurement of C-reactive protein could facilitate this diagnosis.	28226029
Malignant Peripheral Nerve Sheath Tumor, JAK2 NP_004963.1:p.V617F, Inflammation, Myeloproliferative disease	Altered Intercellular Communication	The driver mutations JAK2V617F, MPLW515L/K and CALR influence disease phenotype of myeloproliferative neoplasms (MPNs) and might sustain a condition of chronic inflammation.	28228104
JAK2 NP_004963.1:p.V617F, Inflammation	Altered Intercellular Communication	These results provide evidence that JAK2V617F mutation influences MPN-associated inflammation with a strong correlation between allele burden and PTX3 levels.	28228104
Inflammation, Endothelial dysfunction, Vascular Diseases	Altered Intercellular Communication	Endothelial dysfunction and inflammation are key mechanisms of vascular disease.	28229168
ACSM3 gene, Inflammation	Altered Intercellular Communication	This study showed an early increased sTREM-1 CSF level in SAH patients, which correlated with inflammation intensity post-SAH and clinical severity, indicating that TREM-1 may participate in the inflammatory mechanisms of EBI.	28229304
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Routine 18F-FDG PET/CT does not detect inflammation in the left atrium in patients with atrial fibrillation.	28229312
Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Increasing evidence supports a role of inflammation in the development of atrial fibrillation (AF).	28229312
Inflammation	Altered Intercellular Communication	Contrary to previous reports, these results therefore do not clearly support a role for ongoing atrial inflammation in patients with AF.	28229312
PROS1 gene, Arthritis, Psoriatic	Altered Intercellular Communication	Psoriatic arthritis (PsA) is a variable and complex inflammatory condition.	28229377
Inflammation	Altered Intercellular Communication	Honokiol protects skin cells against inflammation, collagenolysis, apoptosis, and senescence caused by cigarette smoke damage.	28229451
Inflammation	Altered Intercellular Communication	Honokiol protects both HFF-1 and HaCat against cigarette smoke-induced inflammation, collagenolysis, apoptosis, and senescence.	28229451
Inflammation	Altered Intercellular Communication	SHARPIN, SHANK-associated RH domain interacting protein, associates with a linear ubiquitin chain assembly complex (LUBAC) to regulate inflammation and immunity.	28230260
Cardiovascular system	Altered Intercellular Communication	Basigin (BSG) promotes cardiovascular inflammation and myocardial remodeling processes by induction of extracellular matrix metalloproteinases and inflammatory cytokines.	28230811
Airway structure	Altered Intercellular Communication	Asthma is characterized by a heterogeneous inflammatory profile and can be subdivided into T(h)2-high and T(h)2-low airway inflammation.	28231834
Inflammation, FBN2 wt Allele	Altered Intercellular Communication	Ov-associated CCA is the culmination of chronic Ov-infection, with the persistent production of the growth factors and cytokines associated with persistent inflammation, which can endure for years in Ov-infected individuals prior to transitioning to CCA.	28232516
Primary malignant neoplasm, FBN2 wt Allele	Altered Intercellular Communication	The profile of protein dysregulation observed during chronic Ovinfection and then in Ov-induced CCA provides insight into the etiology of an infection-induced inflammation-related cancer.	28232516
atherosclerotic	Altered Intercellular Communication	18F-FDG is the most widely validated PET tracer for the evaluation of atherosclerotic inflammation.	28232606
Inflammation, Atherosclerosis	Altered Intercellular Communication	We aimed to analyze the association between inflammation and osteogenesis at different stages of atherosclerosis, as well as the interrelationship between these 2 processes during disease progression.	28232606
Inflammation, Atherosclerosis	Altered Intercellular Communication	The association between inflammation and osteogenesis during atherosclerosis progression was evaluated in 19 patients who had at least 2 examinations with both tracers.	28232606
vascular inflammations	Altered Intercellular Communication	Most noncalcified (86%) and mildly calcified (81%) lesions and 47% of severely calcified lesions had concordant development of both vascular inflammation and osteogenesis.	28232606
Communicable Diseases, Hemorrhage, Inflammation, Extravasation	Altered Intercellular Communication	Wound healing was achieved in all patients, with no case of wound infection, bleeding, leakage or inflammation.	28233056
Inflammation, Malnutrition, Edema, Fracture	Altered Intercellular Communication	In addition, (S) had higher state of inflammation (erythrocyte sedimentation rate: p < 0.05 and C-reactive protein: p < 0.01), and an increase of risk of fractures (FRAX: OR 1.07; p < 0.001), risk of malnutrition (mini nutritional assessment: p < 0.001), and risk of edema (extra cellular water: p < 0.001).	28233283
Inflammation, Sarcopenia, Malnutrition, Edema	Altered Intercellular Communication	Sarcopenia is closely linked to an increase in the risk of hip-femur fractures, inflammation, edema, and malnutrition.	28233283
Allergic sensitization, Sinusitis	Altered Intercellular Communication	Allergic sensitization does not predispose to sinus inflammation in externalized paranasal sinuses.	28234140
Inflammation, Hypersensitivity, Neoplasms	Altered Intercellular Communication	Externalization of the sinuses in patients with inhalant allergy did not bring about significant additional inflammation in patients after tumor surgery.	28234140
Inflammation, MS4A2 wt Allele	Altered Intercellular Communication	The patients with CRSwNP and with atopy but not the patients with CRSsNP and with atopy demonstrated systemic eosinophilic inflammation.	28234143
Inflammation, Adenolymphoma	Altered Intercellular Communication	Inflammation following invasive procedures for Warthin's tumour: A retrospective case series.	28235157
Inflammation, Adenolymphoma	Altered Intercellular Communication	To determine the risk of inflammation associated with fine-needle aspiration during evaluation of Warthin's tumour.	28235157
Parotid Neoplasms, Adenolymphoma, Inflammation	Altered Intercellular Communication	Warthin's tumour is associated with a tenfold higher risk of inflammation compared to other parotid tumours following invasive procedures.	28235157
Inflammation, Depression, CTCAE	Altered Intercellular Communication	The association between DGLA and depression was not dependent on inflammation (P-interaction=0.618).	28235735
Inflammation, Calcified (qualifier)	Altered Intercellular Communication	The side-specific progression of the disease is characterized by inflammation, calcific lesions, and extracellular matrix (ECM) degradation.	28236165
Inflammation, Toxic effect	Altered Intercellular Communication	Neither toxicity nor inflammation from RGD.Flt23k.NP was detected.	28236576
PEX19 gene, Inflammation, Zonular dehiscence	Altered Intercellular Communication	The following complications occurred more frequently in PXF cases: zonular dehiscence without vitrectomy (4 [3.3%] PXF cases vs 40 [0.8%] non-PXF cases p = 0.02), persistent inflammation (28 [24.1%] vs 668 [14.5%]; p = 0.007), and persistent intraocular pressure elevation (5 [4.3%] vs 68 [1.5%]; p = 0.03).	28237151
PROS1 gene, Inflammation, Arthritis, Psoriatic, Psoriasis	Altered Intercellular Communication	The factors that contribute to the development of psoriatic arthritis (PsA) among patients with psoriasis are not well known; however, systemic inflammation is believed to be important.	28237512
Minimal Disseminated Disease, Depressive disorder, Inflammation, Psoriasis	Altered Intercellular Communication	On the basis of recent laboratory work demonstrating that major depressive disorder (MDD) is associated with increased systemic inflammation, we hypothesized that patients with psoriasis who develop MDD are at increased risk of subsequently developing PsA.	28237512
Schizophrenia	Altered Intercellular Communication	Chronic low-grade peripheral inflammation is associated with severe nicotine dependence in schizophrenia: results from the national multicentric FACE-SZ cohort.	28238173
Seizures, Inflammation, Impaired cognition, Schizophrenia	Altered Intercellular Communication	Chronic peripheral inflammation (CPI) has been associated with cognitive impairment in schizophrenia (SZ).	28238173
Chronic hemolytic anemia, Inflammation, SLC22A5 gene	Altered Intercellular Communication	Manifestations of SCD include chronic hemolytic anemia, inflammation, painful vaso-occlusive crises, multisystem organ damage, and reduced life expectancy.	28238805
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	The initial mucosal biopsy finding was chronic inflammation, but we were highly suspicion of malignancy; we performed an endoscopic mucosal resection.	28239083
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	To optimise treatment of ulcerative colitis (UC), patients need repeated assessment of mucosal inflammation.	28239876
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	VOCs have demonstrated potential as new non-invasive biomarker to monitor inflammation in UC.	28239876
Inflammation, Fasciitis, Contracture, Polyarthritis	Altered Intercellular Communication	Palmar fasciitis and polyarthritis syndrome (PFPAS) is an uncommon disorder characterized by diffuse inflammation of the palmar fascia, tendon sheaths, and joints of the fingers and wrists, which rapidly progresses to flexion contracture of the hands.	28239882
palladium, Inflammation	Altered Intercellular Communication	Our study indicates a state of systemic inflammation and oxidative stress in PD patients coupled with alterations in Fe metabolism.	28240188
palladium, Inflammation	Altered Intercellular Communication	Chronic inflammation and oxidative pathways in PD may in part determine changes in iron metabolism.	28240188
Endothelial dysfunction	Altered Intercellular Communication	In conclusion, as GFR declines Cat-S and markers of inflammation-related endothelial dysfunction increase.	28240259
Chronobiology Disorders, Migraine with Aura, physiopathological	Altered Intercellular Communication	The neurological disturbances of migraine aura are caused by transient cortical dysfunction due to waves of spreading depolarization that disrupt neuronal signaling.	28240389
Respiratory Distress Syndrome, Adult, Pneumonitis	Altered Intercellular Communication	Early treatment with inhaled corticosteroids and beta agonists may reduce progression to acute respiratory distress syndrome by reducing lung inflammation and enhancing alveolar fluid clearance.	28240689
Inflammation, Fibrosis Assessment, Heart failure	Altered Intercellular Communication	Galectin-3, a novel binding-lectin involved in inflammation and fibrosis, is elevated in heart failure and is independently predictive of mortality in this condition.	28242288
Communicable Diseases, Inflammation	Altered Intercellular Communication	The surgical exploration revealed no signs of inflammation or infection and excluded any endoleak, confirming the term "endotension".	28242401
ARCN1 gene, Inflammation	Altered Intercellular Communication	The major characteristic of COPD is systemic inflammation.	28243079
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Obesity increases the risk for non-alcoholic fatty liver disease through adipokine dysregulation and inflammation.	28244519
Inflammation	Altered Intercellular Communication	It plays a central role in many biological processes, including protein folding, host-pathogen interactions, immune response, and inflammation.	28244758
ARCN1 gene, Inflammation	Altered Intercellular Communication	This association was maintained after additionally adjusting for baseline CVD risk, for co-morbidities and descriptors of COPD severity and impact, markers of cardiac stress (N-terminal pro-B-type natriuretic peptide, troponin T) and of inflammation (Interleukin-6), and in subgroup analysis excluding men, diabetics, current smokers or those with limited ambulation.	28245821
Inflammation, Sample Size Calculation, Epstein-Barr Virus Infections	Altered Intercellular Communication	Immunogenicity of infectious EBV suggests a novel mechanism mediating monocyte inflammation in SSc, by which EBV triggers the innate immune response in infected cells.	28245863
Inflammation, Metabolic Diseases	Altered Intercellular Communication	Assessment of the comprehensive relationship among apolipoprotein CIII (apoCIII) levels, inflammation, and metabolic disorders is rare.	28245894
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	A mediation analysis was used to detect the underlying role of apoCIII in the association of inflammation with metabolic syndrome (MetS).	28245894
Inflammation	Altered Intercellular Communication	To collaborate in the understanding of the biochemical mechanisms involved in the synovial inflammation process.	28245911
Inflammation, Malignant Neoplasms, Cerebrovascular accident	Altered Intercellular Communication	Our analysis suggests that a multiple algorithm combining the number of territories involved and laboratory signs of inflammation and cell turnover might identify patients with stroke suffering from previously unknown malignancy.	28247043
Inflammation, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	Incorporating Inflammation into Mortality Risk in Pediatric Acute Respiratory Distress Syndrome.	28248715
Inflammation, Lung Injury, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	In pediatric acute respiratory distress syndrome, lung injury is mediated by immune activation and severe inflammation.	28248715
Inflammation, Liver damage	Altered Intercellular Communication	The Role of Inflammation in the Mechanisms of Bile Acid-Induced Liver Damage.	28249287
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The role of inflammation has been established in cancer biology and the neutrophil to lymphocyte ratio postulated as a marker of systemic inflammatory response.	28249912
Inflammation, Metabolic Syndrome X, Atherosclerosis	Altered Intercellular Communication	Semaphorin-3E, provoking inflammation and insulin resistance which leads to metabolic syndrome, exerts obscure effects on carotid atherosclerosis in metabolic syndrome.	28249916
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Although many studies have examined the role of chronic inflammation in cancer development, few studies discuss the patterns of acute inflammation prior to cancer diagnosis.	28250427
Inflammation, Postoperative Complications, Saint Lucia	Altered Intercellular Communication	Patients with more severe inflammation according to Tokyo Criteria grade were more likely to undergo PC, were more likely to be readmitted while waiting for LC, and also had more postoperative complications.	28251270
allergic inflammation	Altered Intercellular Communication	Haemopoietic progenitor cells (HPC) migrate to sites of allergic inflammation where, upon stimulation with epithelial cytokines, they produce Th2 cytokines and differentiate into mature eosinophils and basophils.	28252235
Inflammation	Altered Intercellular Communication	Thus, implementation and maintenance of similar exercise programs can contribute to reduce chronic inflammation among obese postmenopausal women.	28253046
Inflammation, Fibrosis Assessment, Fatty degeneration, Fatty Liver Disease	Altered Intercellular Communication	Despite having more steatosis and inflammation, progression of fibrosis was slower in NASH compared with ALD recipients.	28253211
Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Our data suggest that luseogliflozin could reduce the EFV in parallel with the improvement of systemic micro-inflammation and the reduction of body weight in Japanese patients with type 2 diabetes.	28253918
Inflammation, Neurogenic arthropathy, Osteolysis	Altered Intercellular Communication	Persistent inflammation with pedal osteolysis 1year after Charcot neuropathic osteoarthropathy.	28254346
Inflammation, Neurogenic arthropathy, Peripheral Neuropathy, Diabetes Mellitus	Altered Intercellular Communication	To determine local and systemic markers of inflammation and bone mineral density (BMD) in the foot and central sites in participants with diabetes mellitus and peripheral neuropathy (DMPN) with and without acute Charcot neuropathic osteoarthropathy (CN).	28254346
Inflammation, Foot Deformities, Osteolysis	Altered Intercellular Communication	Local and systemic inflammation persists 1 year after CN with an accompanying pedal osteolysis that may contribute to mid foot deformity which is the hallmark of the chronic Charcot foot.	28254346
Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers.	28255100
Traumatic injury, Paralysed	Altered Intercellular Communication	Impaired expression of TLRs and HLA-DR in acute inflammatory conditions may be responsible for the well-described monocyte paralysis after severe trauma.	28255201
ARCN1 gene, Inflammation, Muscular Atrophy	Altered Intercellular Communication	Muscle wasting and chronic inflammation are predominant features of patients with COPD.	28255238
Inflammation	Altered Intercellular Communication	Systemic inflammation is associated with an accelerated decline in lung function.	28255238
ARCN1 gene, Inflammation, Sarcopenia	Altered Intercellular Communication	Systemic inflammation could be an important contributor to sarcopenia in the stable COPD population.	28255238
ARCN1 gene, Sarcopenia	Altered Intercellular Communication	In this study, the prevalence of sarcopenia and the relationships between sarcopenia and systemic inflammations in patients with stable COPD were investigated.	28255238
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases	Altered Intercellular Communication	Systemic inflammation is involved in the development of several diseases, including cardiovascular disease and type 2 diabetes.	28255731
Coma, Post-Head Injury, Inflammation	Altered Intercellular Communication	Treatment of critical-sized, post-traumatic, acute wounds with OASIS resulted in decreased inflammation, and potentially more advanced wound healing, compared to SOC.	28256051
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	These results, albeit preliminary and involving a small number of patients, are consistent with reports showing the presence of susceptibility loci within the HLA gene region for several inflammatory and autoimmune diseases, and with our previous findings indicating that the increased sensitivity to DOX cardiotoxicity was associated with dysregulation of genes implicated both in inflammation and autoimmune disorders.	28256194
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Its etiology and pathogenesis appear to be related to chronic inflammation in the affected area, prior surgery, or systemic disease, particularly rheumatoid arthritis.	28256202
Inflammation, Coronary Arteriosclerosis, atherosclerotic	Altered Intercellular Communication	Given the body of evidence implicating inflammation in atherosclerotic process, we hypothesized that procalcitonin (PCT) as an inflammatory marker may be related to coronary atherosclerotic burden.	28256322
Inflammation, Atherosclerosis	Altered Intercellular Communication	Treatment of local inflammation and reduction of systemic inflammatory markers are believed to lower the diagnostic criteria for atherosclerosis as well.	28256493
Giant Cell Arteritis, vascular inflammations	Altered Intercellular Communication	Although clinical signs and symptoms of giant cell arteritis improve promptly after starting glucocorticoid therapy, reports have suggested that the vascular inflammation may persist.	28256573
Granulomatous inflammation	Altered Intercellular Communication	Granulomatous inflammation decreased in a time-dependent manner from 78 to 100% at initial biopsy to 50% at 9 months and 25% at 12 months.	28256573
Inflammation, Secondary glaucoma, Lens Opacities	Altered Intercellular Communication	To report a case of conjunctival tattooing for cosmetic purposes with inadvertent globe penetration resulting in severe inflammation, capsular lens opacity, and secondary glaucoma.	28257383
Inflammatory abnormality of the eye	Altered Intercellular Communication	The patient underwent clinical and surgical treatments to control ocular inflammation and intraocular pressure.	28257383
Inflammation, Secondary glaucoma, Lens Opacities	Altered Intercellular Communication	An unusual case of conjunctival tattooing resulted in severe inflammation, capsular lens opacity, and secondary glaucoma.	28257383
Cardiac Arrest, Inflammation	Altered Intercellular Communication	Two mechanisms may explain that iron deposition largely spares the heart in SCA: the high level of erythropoiesis recycles the iron and the chronic inflammation retains iron within the macrophages.	28257476
Inflammation, Miller Dieker syndrome	Altered Intercellular Communication	Iron accumulation varies widely in MDS syndromes due to the competing influences of abnormal erythropoiesis, excess iron supply, and inflammation.	28257476
Antisynthetase syndrome, Arthritis, Lung Diseases, Interstitial, Myositis	Altered Intercellular Communication	Antisynthetase syndrome is a rare and debilitating multiorgan disease characterized by inflammatory myopathy, interstitial lung disease, cutaneous involvement, and frequent chronic inflammation of the joints.	28257650
Diabetes Mellitus	Altered Intercellular Communication	The association of vitamin D status and inflammation prediabetes mellitus (PreDM) individuals has not been investigated.	28259644
Inflammation, Impaired cognition, ETV3 wt Allele	Altered Intercellular Communication	This longitudinal study investigates whether MetS or its components affect cognitive decline in aging men and whether any interaction with inflammation exists.	28259698
Inflammation, Impaired cognition, ETV3 wt Allele	Altered Intercellular Communication	No evidence was found for a relationship between MetS or inflammation and cognitive decline in this sample of aging men.	28259698
Inflammation	Altered Intercellular Communication	Inflammation in the retinal pigment epithelium is an important contributor to the pathogenesis of age-related macular degeneration.	28260013
Inflammation, Aortic valve calcification, Congenital bilateral aplasia of vas deferens, Aortic valve disorder	Altered Intercellular Communication	Chronic inflammation and the calcification of aortic valve interstitial cells (AVICs) are the primary etiologies of calcific aortic valve disease (CAVD).	28260034
Inflammation, Calcinosis	Altered Intercellular Communication	The present study investigated the importance of high mobility group box 1 (HMGB1) via toll-like receptor 4 (TLR4) for the regulation of inflammation and calcification in AVICs.	28260034
Inflammation, Obesity	Altered Intercellular Communication	Obesity is associated with chronic, low grade, systemic inflammation.	28260748
Airway structure, Craniosynostosis	Altered Intercellular Communication	CRS was associated with COPD-Bx and this was probably due to increased airway inflammation.	28260873
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Should Alvarado and Ohmann scores be real indicators for diagnosis of appendicitis and severity of inflammation?	28261767
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Alvarado score is better able to predict acute appendicitis and provide an idea of severity of inflammation.	28261767
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Galectin 3 (Gal 3) is a b-galactoside-binding lectin known to play a part in inflammation, adverse remodeling and fibrosis.	28262193
Mastocytosis, Allergy - Charge Type Reason	Altered Intercellular Communication	Mast cell activation syndrome (MCAS), a recently recognized nonneoplastic mast cell disease driving chronic multisystem inflammation and allergy, appears prevalent and thus important.	28262205
Inflammation	Altered Intercellular Communication	Even though it has been suggested that low doses of radiation may attenuate chronic inflammation, the underlying mechanisms remain elusive.	28263099
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Its deficiency results in accumulation of self-DNA, which in turn may induce inflammation and autoimmunity.	28263100
Myocarditis	Altered Intercellular Communication	Uptake of the radiopharmaceutical F-FDG visualized by PET imaging can reflect abnormal myocardial inflammation.	28263213
Inflammatory Bowel Diseases, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Intestinal Inflammation Does Not Predict Nonalcoholic Fatty Liver Disease Severity in Inflammatory Bowel Disease Patients.	28265826
Non-alcoholic Fatty Liver Disease, Metabolic Syndrome X, Gastrointestinal inflammation, ETV3 wt Allele	Altered Intercellular Communication	Both metabolic syndrome (MetS) and intestinal inflammation are implicated in NAFLD pathogenesis.	28265826
Inflammation, Myelitis, Transverse	Altered Intercellular Communication	Its key features include transverse myelitis, commonly associated with extensive inflammation spanning three or more consecutive vertebral segments.	28266199
Inflammation	Altered Intercellular Communication	The inflammation seems self-limited, while the role of anti-inflammatory drugs remains obscure.	28266289
Inflammation	Altered Intercellular Communication	When present in the setting of hypervascularity and/or evidence of active inflammation, the risk increased further to 15-fold.	28267043
Inflammation	Altered Intercellular Communication	Cases had more evidence of inflammation based on higher Harvey Bradshaw Index values and inflammatory biomarkers and lower hemoglobin values.	28267043
AURKAIP1 gene, Pancreatitis	Altered Intercellular Communication	Although CP and type 1 AIP are both characterized by the presence of sustained pancreatic inflammation, they are different in terms of the density and hypertrophy of intrapancreatic nerve fibers.	28270361
Inflammation, Fibrosis Assessment, Abrasion	Altered Intercellular Communication	Pleurodesis is commonly accomplished by draining the pleural fluid, if present, followed by either a mechanical procedure, such as abrasion, pleurectomy, or instillation of a chemical irritant into the pleural space, which results in inflammation and fibrosis which obliterates the pleural space.	28271362
Inflammation, Cancer-related Cognitive Dysfunction, Memory difficulties	Altered Intercellular Communication	Results suggest that high levels of inflammation alone are not sufficient to account for cognitive difficulties, but may interact with other factors in at-risk populations like LLD, to contribute to memory difficulties.	28271543
Inflammation, Spondylitis	Altered Intercellular Communication	Successful adalimumab treatment and usefulness of capsule endoscopy for gut inflammation concomitant with ankylosing spondylitis.	28271948
Inflammation, Spondylitis	Altered Intercellular Communication	Here we describe a 20-year-old man with ankylosing spondylitis and gut inflammation, who was successfully treated with adalimumab.	28271948
Inflammation, Spondylitis	Altered Intercellular Communication	Adalimumab might be an effective treatment for gut inflammation related to ankylosing spondylitis.	28271948
Inflammation	Altered Intercellular Communication	Mediators of Inflammation in Asthma: A Forensic Perspective.	28272089
Inflammation, Asthma	Altered Intercellular Communication	In the clinical setting, the role of systemic inflammation in patients with asthma has attracted increased attention, and some authors showed that increased IL-6 and high-sensitivity C-reactive protein characterized a group of asthmatic patients.	28272089
Cessation of life, Inflammation, Asthma	Altered Intercellular Communication	A total of 35 autopsy cases were retrospectively selected and included deaths in asthmatic subjects (related and unrelated to severe acute bronchial asthma, in situations characterized or not by systemic inflammation) as well as deaths in nonasthmatic individuals (in situations characterized or not by systemic inflammation).	28272089
Cessation of life, Inflammation, Asthma	Altered Intercellular Communication	Accordingly, postmortem serum IL-6 values in cases of death during severe acute bronchial asthma can be measured and considered of diagnostic relevance to estimate the magnitude of the systemic inflammation responses characterizing the disease.	28272089
Inflammation, Granuloma	Altered Intercellular Communication	In spite of a good safety profile, biologic TNF antagonists may induce paradoxical inflammation, which can manifest as sarcoid-like granulomatosis, consisting of noncaseating granulomas in the affected organs.	28272203
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	This study suggests an association between frailty and inflammation in older adults with cancer.	28273043
Inflammation, Asthma, Allergic	Altered Intercellular Communication	IL-33 is a tissue-derived cytokine that induces and amplifies eosinophilic inflammation and has emerged as a promising new drug target for asthma and allergic disease.	28273074
Inflammation, Transitional cell carcinoma of bladder	Altered Intercellular Communication	Role of Inflammation in the Perioperative Management of Urothelial Bladder Cancer With Squamous-Cell Features: Impact of Neutrophil-to-Lymphocyte Ratio on Outcomes and Response to Neoadjuvant Chemotherapy.	28274590
Inflammation, Epithelioma	Altered Intercellular Communication	Neutrophil-to-lymphocyte ratio (NLR) might reflect an increased neutrophilic inflammatory response, and urothelial tumors with squamous-cell features (SqD) have been linked to inflammation.	28274590
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	We calculated relative and absolute risks of CRC for PLP and the ratios 3-hydroxykynurenine:XA (HK:XA), an inverse marker of functional vitamin B-6 status, and PA:(PLP + pyridoxal) (PAr), a marker of inflammation and oxidative stress and an inverse marker of vitamin B-6 status.Results: Plasma PLP concentrations were associated with a reduced CRC risk for the third compared with the first quartile and for PLP sufficiency compared with deficiency [OR: 0.60 (95% CI: 0.44, 0.81) and OR: 0.55 (95% CI: 0.37, 0.81), respectively].	28275126
Inflammation, Neoplasms	Altered Intercellular Communication	Furthermore, our analyses of novel markers of functional vitamin B-6 status and vitamin B-6-associated oxidative stress and inflammation suggest a role in tumor progression rather than initiation.	28275126
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation has further been linked to atrial fibrillation (AF).	28276729
Perifolliculitis	Altered Intercellular Communication	All consenting household residents aged 1 year and above were examined for trachomatous inflammation-follicular (TF), trachomatous inflammation-intense (TI) and trichiasis.	28276755
amyloid-beta binding, Inflammation, Cognition Disorders, Blood Circulation	Altered Intercellular Communication	In the brain, amyloid-beta generation participates in the pathophysiology of cognitive disorders; in the bloodstream, the role of amyloid-beta is uncertain but may be linked to sterile inflammation and senescence.	28279654
Inflammation, physiopathological	Altered Intercellular Communication	These findings indicate that circulating levels of LCN-2 in patients after AP may play a role in chronic low grade inflammation associated with abdominal adiposity and that alcohol consumption may further exacerbate adipose tissue dysfunction.	28279688
Inflammation	Altered Intercellular Communication	Kcne2 deletion also caused extensive pancreatic transcriptome changes consistent with facets of T2DM, including endoplasmic reticulum stress, inflammation, and hyperproliferation.	28280005
Inflammation, Neoplasms	Altered Intercellular Communication	Emerging evidence suggests that p53 dysfunction also fuels inflammation and supports tumor immune evasion, thereby serving as an immunological driver of tumorigenesis.	28280037
Inflammation, Observation Method - Coagulation, Atherosclerosis	Altered Intercellular Communication	Inflammation, coagulation, and cell stress contribute to atherosclerosis and its adverse events.	28280039
Airway structure, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In infants and young children with cystic fibrosis, lower airway infection and inflammation are associated with adverse respiratory outcomes.	28280235
Airway structure, Fibrosis Assessment	Altered Intercellular Communication	Detection of recognised cystic fibrosis bacterial pathogens was associated with reduced microbial diversity and greater lower airway inflammation.	28280235
Airway structure, Fibrosis Assessment	Altered Intercellular Communication	Dominance of the microbiota by recognised cystic fibrosis bacterial pathogens is associated with increased lower airway inflammation, however early microbial diversity is not associated with pulmonary function at 6 years of age.	28280235
Inflammation, acetate-CoA ligase activity, Calcification of coronary artery	Altered Intercellular Communication	In the present study, we explored the relationship between the NLR and CACS in terms of subclinical inflammation and coronary artery calcification.	28280728
Inflammation, Choroiditis	Altered Intercellular Communication	Multimodal imaging shows that inflammation of the choriocapillaris is a main pathology of serpiginous choroiditis.	28281863
Chronic kidney disease stage 5, Inflammation, Kidney Failure, Chronic	Altered Intercellular Communication	Additionally, it is known that peritoneal inflammation can be correlated with systemic inflammation and this could contribute to the compromised rHuEPO required dose in anemic patients with end stage renal disease (ESRD).	28282547
Kidney Failure, Chronic, Inflammation, Anemia	Altered Intercellular Communication	Our study found increased IL-17 and IFN-g plasma, but no dialysate levels, in patients receiving higher doses of rHuEPO, suggesting may exist a relationship between systemic inflammation of ESRD, and the necessary levels of rHuEPO for the correction of anemia in these patients.	28282547
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Het OTC-KO female mice showed evidence of liver inflammation and the eventual development of significant fibrosis.	28283349
Impaired cognition, Zebrafish	Altered Intercellular Communication	The present results: a. reveal regional differences in de-regulated gene expression between the anterior horn of the spinal cord and frontal cortex area 8 in the same individuals suffering from sALS; b. validate and extend our knowledge about the complexity of the inflammatory response in the anterior horn of the spinal cord; and c. identify for the first time extensive gene up-regulation of neurotransmission and synaptic-related genes, together with significant down-regulation of oligodendrocyte- and myelin-related genes, as important contributors to the pathogenesis of frontal cortex alterations in the sALS/frontotemporal lobar degeneration spectrum complex at stages with no apparent cognitive impairment.	28283675
Gastrointestinal inflammation	Altered Intercellular Communication	It is suggested that AIM may contribute to intestinal inflammation by inhibiting the apoptosis of macrophages.	28284201
Inflammation, Neuromyelitis Optica, MS gene	Altered Intercellular Communication	Soluble CD40 ligand contributes to blood-brain barrier breakdown and central nervous system inflammation in multiple sclerosis and neuromyelitis optica spectrum disorder.	28284329
Inflammation	Altered Intercellular Communication	sCD40L could be involved in BBB disruption in MS, whereas it may contribute to CNS inflammation in NMOSD.	28284329
Inflammation, Axonal neuropathy, Demyelination, Inflammatory disorder	Altered Intercellular Communication	Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS), where inflammation, demyelination together with the axonopathy are the cardinal features on pathologic ground, with a combined genetic and environmental background.	28284331
Chronic lymphocytic inflammation, Pontine structure, Clippers	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS): A lymphocytic reactive response of the central nervous system?	28284348
Chronic lymphocytic inflammation, Pontine structure, Clippers	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroid (CLIPPERS) was first described in 2010.	28284348
Acute myocardial infarction, Left ventricular systolic dysfunction	Altered Intercellular Communication	Increased levels of neuro-hormonal biomarkers predict poor prognosis in patients with acute myocardial infarction (AMI) complicated by left ventricular systolic dysfunction (LVSD).	28284500
Structure of suprasellar region, Impaired cognition, Pituitary Adenoma	Altered Intercellular Communication	Patients suffering from pituitary adenomas may experience cognitive dysfunctions due to hormonal imbalance or suprasellar tumor extension displacing neural structures.	28284581
Inflammation, Empyema	Altered Intercellular Communication	Acute inflammation with empyema and peripancreatic liquid collection was observed in 14 patients (12 in Group 1, 2 in Group 2), and conversion to OS was statistically significantly higher in Group 1 (p=0.016).	28284749
Inflammation, Periodontitis, "Alzheimers Disease", Data types - Address, Periodontal Diseases	Altered Intercellular Communication	Although the pathogeneses of Alzheimer's disease (AD) and periodontal diseases have overlapping features, including ageing and chronic inflammation, the association between AD and periodontitis remains unclear.	28285126
Enteritis	Altered Intercellular Communication	Patients with increased permeability (n = 39) and randomly selected subjects with normal permeability (n = 59) were then examined by VCE for signs of small bowel inflammation and subclinical CD.	28286191
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Severity of inflammation in patients with UC was assessed by Mayo score and in patients with CD by 4-grade system.	28286192
Inflammation, Crypt abscess, Ulceration, CTCAE, Superficial ulcer	Altered Intercellular Communication	Biopsies were assessed for signs of active inflammation, erosion or ulceration, and crypt abscesses and assigned a histologic score.	28286192
Superficial ulcer, Inflammation, Ulcer	Altered Intercellular Communication	At Week 52, a total of 38 patients (54.3%) were still in clinical remission or still had a clinical response; 29 patients (41.4%) had mucosal healing, defined as complete healing of erosions or ulcerations, and 20 patients (27.7%) had histologic healing, defined as complete absence of markers of inflammation.	28286192
Inflammation, Lupus Erythematosus, Bacterial Infections, Lupus Erythematosus, Systemic	Altered Intercellular Communication	C-reactive protein (CRP), a marker for inflammation, indicates bacterial infection in systemic lupus erythematosus (SLE) when markedly elevated.	28286229
Inflammation	Altered Intercellular Communication	PKC-epsilon and TLR4 synergistically regulate resistin-mediated inflammation in human macrophages.	28286252
Cardiac complication, atherosclerotic	Altered Intercellular Communication	Resistin has been associated with atherosclerotic inflammation and cardiovascular complications.	28286252
Inflammation	Altered Intercellular Communication	PKCe is a key upstream mediator in resistin-induced inflammation that may interact synergistically with TLR4 to promote NF-kB activation, while TRAM is an important signal.	28286252
atherosclerotic	Altered Intercellular Communication	PKCe and TRAM may represent novel molecular targets for resistin-associated chronic atherosclerotic inflammation.	28286252
Sepsis, Inflammation	Altered Intercellular Communication	Natural killer (NK) cells play a crucial role in the pathophysiology of sepsis, leading to exaggerated inflammation due their rapid response and production of pro-inflammatory cytokines such as interferon gamma (IFN-g).	28287491
Malnutrition, Inflammation, Atrophy of thymus gland	Altered Intercellular Communication	Malnutrition and inflammation are associated with thymus atrophy, and thymus area seems positively associated with plasma phosphate.	28288591
Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	The kinin system is activated during vasculitis and may contribute to chronic inflammation.	28289183
Inflammation, Hormone Receptor Positive Breast Carcinoma	Altered Intercellular Communication	Thus, B1 receptor-positive endothelial microvesicles may contribute to chronic inflammation by inducing neutrophil chemotaxis, and the reduction of these microvesicles by C1-inhibitor should be explored as a potential treatment for neutrophil-induced inflammation.	28289183
Inflammation, diabetic ulcer	Altered Intercellular Communication	In particular, defective transition from pro-inflammatory (M1) to anti-inflammatory (M2) behavior has been implicated as a potential source of sustained inflammation that prevents healing of chronic wounds such as diabetic ulcers.	28290581
Acute Kidney Injury, CTCAE, Inflammation, Pneumonia	Altered Intercellular Communication	Because pneumonia and acute kidney injury are in part mediated by inflammation, we hypothesized that when acute kidney injury complicates pneumonia, major adverse kidney events outcomes would be exacerbated.	28291091
skin damage, Inflammation	Altered Intercellular Communication	As the number of Langerhans cells was not reduced in the undisturbed neighboring skin, the depletion of epidermal Langerhans cells did not precede skin damage but was a cause of prolonged severe inflammation.	28291135
hepcidin, Anemia	Altered Intercellular Communication	Excessive hepcidin signaling causes anemia in chronic inflammatory conditions by restricting iron delivery to the bone marrow.	28291504
Inflammatory Bowel Diseases, Acute inflammation	Altered Intercellular Communication	Caution is warranted in patients with active IBD, since the exact impact of active bowel inflammation could not be determined retrospectively.	28291546
Aggressive course, Inflammation	Altered Intercellular Communication	Intratumoral inflammation was found to be associated with aggressive prostate cancer.	28292923
Inflammation, Prostatic Neoplasms	Altered Intercellular Communication	We and others have shown that prostate tumors in African-American (AA) patients harbor a distinct immune and inflammation signature when compared with European-American (EA) patients.	28292923
Inflammation	Altered Intercellular Communication	Our findings could not be accounted for by psychological distress and suggest that non-CNS cancer may directly and/or indirectly affect the brain via mechanisms such as tumor-induced neurogenesis, inflammation, and/or vascular changes, for example.	28293478
Rheumatoid Arthritis	Altered Intercellular Communication	Semiquantitative Evaluation of Extrasynovial Soft Tissue Inflammation in the Shoulders of Patients with Polymyalgia Rheumatica and Elderly-Onset Rheumatoid Arthritis by Power Doppler Ultrasound.	28293635
Inflammation, Rheumatoid Arthritis, Musculoskeletal Pain	Altered Intercellular Communication	To develop a scoring system for evaluating the extrasynovial soft tissue inflammation of the shoulders in patients with polymyalgia rheumatica (PMR) and elderly-onset rheumatoid arthritis with PMR-like onset (pm-EORA) using ultrasound.	28293635
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Target prediction and network analyses identified several interactions between miRNA targets and biomarkers related to inflammation, angiogenesis and endothelial dysfunction.	28293796
Inflammation, Primary malignant neoplasm, Neoplasms, Obesity	Altered Intercellular Communication	Obesity is associated with tumor promoting pathways related to insulin resistance and chronic low-grade inflammation which have been linked to various disease states, including cancer.	28293912
Gingivitis, Calculi, Dental Plaque	Altered Intercellular Communication	A full-mouth clinical examination was performed in order to assess dental plaque, dental calculus and gingival inflammation.	28294149
Gingivitis, Dental Plaque	Altered Intercellular Communication	All-cause mortality risk were raised with dental plaque, gingival inflammation, >10 missing teeth and functional masticatory units <5.	28294149
Gingivitis, Dental Plaque	Altered Intercellular Communication	All-cancer mortality was positively associated with dental plaque and gingival inflammation.	28294149
Gingivitis, Dental Plaque, Non-Cancer Related Death	Altered Intercellular Communication	Non-cardiovascular and non-cancer mortality were also positively associated with high dental plaque (HR = 3.30, [95% CI: 1.76-6.17]), high gingival inflammation (HR = 2.86, [95% CI: 1.71-4.79]), >10 missing teeth (HR = 2.31, [95% CI: 1.40-3.82]) and functional masticatory units <5 (HR = 2.40 [95% CI 1.55-3.73]).	28294149
Inflammation, Neurotoxicity Syndromes	Altered Intercellular Communication	Our findings propose neuronal microtubule instability as a novel mechanism of HIV neurotoxicity, without evidence of enhanced inflammation.	28295345
Uremia, Inflammation, Malnutrition, Infection	Altered Intercellular Communication	Infections in hemodialysis patients are mainly caused by venous catheters, uremia, malnutrition and inflammation.	28296195
Inflammation, "Extra-osseous Ewings sarcoma	Altered Intercellular Communication	Given that GCTs occur at sites of scarring and inflammation, we sought to determine the prevalence of EoE in patients with esophageal GCTs.	28296675
ACSM3 gene, Inflammation, Subarachnoid Hemorrhage, Aneurysmal	Altered Intercellular Communication	Reduction of inflammation after administration of interleukin-1 receptor antagonist following aneurysmal subarachnoid hemorrhage: results of the Subcutaneous Interleukin-1Ra in SAH (SCIL-SAH) study.	28298024
Inflammation, Brain Injuries, ASAH1 gene, Cerebral Ischemia	Altered Intercellular Communication	Inflammation, mediated by the cytokine interleukin-1 (IL-1), is an important contributor to cerebral ischemia after diverse forms of brain injury, including aSAH.	28298024
Inflammation, ASAH1 gene	Altered Intercellular Communication	The authors hypothesized that administration of additional subcutaneous IL-1Ra would reduce inflammation and associated plasma markers associated with poor outcome following aSAH.	28298024
Inflammation, Abnormality of carotid artery	Altered Intercellular Communication	Further imaging with computed tomography and positron emission tomography demonstrated resolution of her left carotid artery abnormality, but new wall thickening and inflammation in her right carotid artery, abdominal aorta, and superior mesenteric artery.	28298242
Myelodysplasia, Vasculitis of large artery, Sore to touch, Inflammation	Altered Intercellular Communication	Large vessel vasculitis in older individuals presenting with atypical clinical features, such as a migratory pattern of affected vessels, vessel wall tenderness, and marked systemic inflammation, should prompt a search for underlying myelodysplasia.	28298242
Airway structure, Chronic Obstructive Airway Disease, Exacerbation	Altered Intercellular Communication	Antimicrobial peptide levels are linked to airway inflammation, bacterial colonisation and exacerbations in chronic obstructive pulmonary disease.	28298400
Communicable Diseases, Inflammation	Altered Intercellular Communication	Antimicrobial peptides (AMPs) are effectors of host defence against infection, inflammation and wound repair.	28298400
ARCN1 gene, Communicable Diseases, Airway structure	Altered Intercellular Communication	In stable COPD, high sputum hCAP18/LL-37 levels were associated with increased risk of AECOPD, non-typeable Haemophilus influenzae colonisation, higher age, ex-smoking and higher levels of inflammatory markers.Altered levels of selected AMPs are linked to airway inflammation, infection and AECOPD, suggesting a role for these peptides in airway defence mechanisms in COPD.	28298400
Herpes Simplex Infections, Inflammation, Communicable Diseases	Altered Intercellular Communication	The absence of markers of inflammation in the cerebrospinal fluid (CSF) commonly predicts the absence of herpes simplex virus (HSV) central nervous system (CNS) infection.	28298450
Inflammation, Obesity, Abdominal, Miller Dieker syndrome	Altered Intercellular Communication	Furthermore, the association between MDS and fasting glucose was fully mediated by adiposity, especially by WC in men aged <45 y and in premenopausal women.Conclusion: Our results suggest that reducing abdominal obesity may play an important role in the pathway through which Med-diet consumption reduces insulin resistance and inflammation.	28298537
Inflammation, Atrial Fibrillation by ECG Finding, osteoclast activating factor	Altered Intercellular Communication	It has been shown that inflammation and oxidative stress are important factors in postoperative atrial fibrillation (POAF).	28299332
Inflammation, Uveomeningoencephalitic Syndrome	Altered Intercellular Communication	The origin of inflammation was primarily in the choroid in VKH and in both the choroid and retina in BRC.	28299496
Inflammation	Altered Intercellular Communication	They constitute chronic low-grade inflammation environment to adjacent cells and tissues.	28299617
Inflammation, Degenerative disorder	Altered Intercellular Communication	Therefore, this compound might be effective in alleviating chronic low-grade inflammation linked to age-related degenerative disorders.	28299617
Suppuration, Inflammation, Hidradenitis	Altered Intercellular Communication	When associated with inflammation, resembling hidradenitis, it is called steatocystoma multiplex suppurativa, a condition rarely reported.	28300893
Kidney Failure, Chronic, Hypothyroidism	Altered Intercellular Communication	End-stage renal disease (ESRD) is associated with perturbations in thyroid hormone concentrations and an increased prevalence of hypothyroidism.	28301073
Community acquired pneumonia	Altered Intercellular Communication	Inflammation biomarkers in blood as mortality predictors in community-acquired pneumonia admitted patients: Importance of comparison with neutrophil count percentage or neutrophil-lymphocyte ratio.	28301543
Inflammation, Community acquired pneumonia	Altered Intercellular Communication	The increase and persistence of inflammation in community-acquired pneumonia (CAP) patients can lead to higher mortality.	28301543
Inflammation, MS gene	Altered Intercellular Communication	MicroRNA-142 regulates inflammation and T cell differentiation in an animal model of multiple sclerosis.	28302134
Inflammation, Squamous cell carcinoma, S100A4 protein, human	Altered Intercellular Communication	Rarely, chronic inflammation and recurrent disease leads to malignant transformation, most commonly to squamous cell carcinoma (SCC).	28302173
Inflammation, Symphysis Pubis Dysfunction	Altered Intercellular Communication	Malignant transformation should be suspected in chronic SPD with recurrent episodes of inflammation, repeated purulent discharge, poor healing, and chronic complex fistulas.	28302173
vascular inflammations, Ischemic stroke, Cerebrovascular accident	Altered Intercellular Communication	In non-cardiogenic ischemic stroke, pravastatin treatment may reduce vascular inflammation as assessed by Hs-CRP, and higher Hs-CRP levels appeared to increase the risk of recurrent stroke and vascular events.	28302952
Inflammation, Pulmonary Hypertension	Altered Intercellular Communication	Inflammation is an increasingly recognized hallmark of pulmonary hypertension (PH).	28303379
Inflammation, Thrombosis	Altered Intercellular Communication	Mean platelets volume (MPV) is a marker, which indicates platelet function, and is a potential link between inflammation and thrombosis.	28303662
Granulomatous inflammation, Necrosis	Altered Intercellular Communication	Lacrimal gland biopsy revealed a perivascular granulomatous inflammation with necrotic foci.	28306365
Inflammation	Altered Intercellular Communication	High physical fitness is associated with reduction in basal- and exercise-induced inflammation.	28314078
Duodenal Adenoma, Inflammation, polyps, Adenocarcinoma of duodenum	Altered Intercellular Communication	Eighteen patients had preoperative diagnosis of duodenal adenomatosis, three patients had preoperative diagnosis of duodenal adenocarcinoma, one had a bleeding polyp and two had localized inflammation.	28314316
Dual-probe in Situ Hybridization, Hyperostosis, Diffuse Idiopathic Skeletal, Calcinosis, Osteogenesis	Altered Intercellular Communication	Diffuse idiopathic skeletal hyperostosis (DISH) is a non-inflammatory condition characterised by calcification and ossification of the vertebral ligaments.	28314808
Stomach Carcinoma, Neoplasms	Altered Intercellular Communication	Inflammation-based indexes and clinicopathologic features are strong predictive values of preoperative circulating tumor cell detection in gastric cancer patients.	28315180
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Conclusion In UC, the new I-SCAN OE technology accurately identified mucosal inflammation, and correlated well with histological scores of chronic and acute changes.	28315280
Inflammation, Primary malignant neoplasm, Esophagitis	Altered Intercellular Communication	HLA-DR expression increased early in the inflammation to cancer progression sequence; with higher expression detected in esophagitis and BE compared to normal tissue.	28315927
TNF protein, human, Inflammation, Degenerative polyarthritis, Refractory anemias	Altered Intercellular Communication	Interestingly, parallel to the severity of inflammation, proinflammatory mediators IL-1b, TNF-a, and 5-LOX specific mRNA as well as immunoreactive (IR) cells were significantly more abundant in patients with RA and JT than in those with OA.	28316377
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	These findings show that upregulation of proinflammatory mediators contributes to the predominantly catabolic inflammatory process in JT and RA synovium, whereas upregulation of anabolic anti-inflammatory mediators counteracts inflammation resulting in the inferior inflammatory process in OA synovium.	28316377
Presenile dementia, Inflammation, Impaired cognition	Altered Intercellular Communication	We hypothesized that poor periodontal health status may be associated with cognitive impairment and dementia via the exacerbation of systemic inflammation.	28317488
Inflammation, Psychiatric	Altered Intercellular Communication	Based on the periodontal and psychiatric examinations and the cytokine levels produced by unstimulated and LPS-stimulated PBL isolated from 128 participants, we have examined if the coexisting of these two clinically described conditions may have influence on the systemic inflammation.	28317488
Inflammation, Impaired cognition	Altered Intercellular Communication	These results confirm that the presence of cognitive decline and the additional source of proinflammatory mediators, like periodontal health problems, aggravate the systemic inflammation.	28317488
Ocular Hypotension, Panuveitis, Inflammatory abnormality of the eye, Uveitis, Tuberculosis, Ocular	Altered Intercellular Communication	Most common type of ocular inflammation causing hypotony was panuveitis (14, 46.6%), and ocular tuberculosis (5; 23.8%) was the most common cause of uveitis in these patients.	28318342
Macular Edema, Cystoid, Inflammation, Uveitis	Altered Intercellular Communication	Clinical Outcomes of Intravitreal Preservative-Free Triamcinolone Preparation (Triesence(r)) for Cystoid Macular Oedema and Inflammation in Patients with Uveitis.	28318344
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	CS patients with LGE alone or in association with FDG were at similar risk of future events, which suggests that outcomes may be driven by the presence of LGE (myocardial fibrosis) and not FDG (inflammation).	28318664
Inflammation, Hemorrhage	Altered Intercellular Communication	This is followed by the proliferation of mesenchymal elements with angiogenesis and inflammation, which in turn becomes a substrate for repeated hemorrhage and expansion of the lesion.	28319470
Hypertensive disease, Inflammation	Altered Intercellular Communication	Finally, mice were exposed to HBP with and without heparin derivatives and the kidneys examined for signs of inflammation.	28319494
Inflammation	Altered Intercellular Communication	MicroRNA-155, which has been shown to play a central role in inflammation and neovascularization, was upregulated with long-term LVAD support.	28319523
Inflammation, Obesity	Altered Intercellular Communication	Obesity is characterized by chronic low-grade inflammation driven by activation and tissue infiltration of circulating leukocytes.	28319586
Inflammation	Altered Intercellular Communication	Oxidative lipid damage is associated with inflammation and the ANS.	28319849
Inflammation, Sample Size Calculation	Altered Intercellular Communication	This signature may provide novel insights linking endothelial inflammation and defective repair processes in the pathogenesis of SSc.	28320472
Chronic Obstructive Airway Disease, Pneumonitis	Altered Intercellular Communication	There is preclinical evidence that consumption of berryfruit extract may reduce chronic airways inflammation and modify airway remodelling in allergen-induced models of lung inflammation.	28320793
Asthma, Eosinophilic inflammation	Altered Intercellular Communication	In steroid-naive participants with mild asthma and elevated FeNO, there was no effect of BFPE on FeNO, a biomarker of eosinophilic airways inflammation.	28320793
Lung Diseases, Interstitial, Pneumonitis	Altered Intercellular Communication	Arterial Carboxyhemoglobin Measurement Is Useful for Evaluating Pulmonary Inflammation in Subjects with Interstitial Lung Disease.	28321059
Pneumonitis	Altered Intercellular Communication	Conclusion The CO-Hb levels of subjects with ILD were increased, particularly during an exacerbation, and were correlated with the parameters that reflect pulmonary inflammation.	28321059
Inflammation, Venous Thromboembolism, vinyltriethoxysilane	Altered Intercellular Communication	Recent gene knockout studies on mice have shown the role of toll-like receptor 9 (TLR9) in resolution of venous thromboembolism (VTE) through sterile inflammation.	28321710
Microalbuminuria, Inflammation	Altered Intercellular Communication	In addition, elevated hs-CRP increased the risk of developing microalbuminuria in subjects with CVD risk factors, indicating that chronic inflammation could amplify the deterioration of kidney by effect of CVD risk factors.	28322017
allergic inflammation	Altered Intercellular Communication	This study shows that IgE levels are associated with DNA methylation levels at numerous CpG sites, which might provide new leads for investigating the links between IgE and allergic inflammation.	28322575
Nephritis	Altered Intercellular Communication	PPARa activation by MHY908 attenuates age-related renal inflammation through modulation of the ROS/Akt/FoxO1 pathway.	28323024
Nephritis	Altered Intercellular Communication	However, the mechanism underlying MHY908-mediated amelioration of renal inflammation with insulin resistance during aging remains unknown.	28323024
Inflammation	Altered Intercellular Communication	One group of thiol containing proteins, peroxiredoxins, in particular, have been associated with inflammation.	28323130
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Inflammation is part of osteoarthritis' pathophysiology, and surgery induces a marked inflammatory response.	28323139
Inflammation, Pain Distress Question	Altered Intercellular Communication	We aimed to investigate whether (1) inflammation is associated with functional performance, knee-extension strength, and knee pain before TKA; (2) PST affects inflammation, and the inflammatory state over time; (3) baseline or surgery-induced inflammation modifies the effect of rehabilitation +- PST on change in 6-min walk test (D6MWT); and (4) baseline or surgery-induced inflammation is associated with D6MWT following TKA.	28323139
Vaginitis	Altered Intercellular Communication	The safety was compared through the results of vaginal findings and vaginal inflammation markers before and after treatment.	28323291
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Inflammation and angiogenesis are a significant element of pathogenesis in rheumatoid arthritis (RA).	28323906
Refractory anemias, Inflammation	Altered Intercellular Communication	The FLT-1- triggering factor for production of proinflammatory cytokines-might contributes to inflammation in patients with RA.	28323906
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Postprandial dysmetabolism in type 2 diabetes (T2D) is exacerbated by prolonged sitting and may trigger inflammation and oxidative stress.	28323950
Inflammation	Altered Intercellular Communication	Compared with SIT, LW and SRA were associated with reductions in lipids associated with inflammation; increased concentrations of lipids associated with antioxidant capacity; and differential changes in species associated with platelet activation.	28323950
Inflammation	Altered Intercellular Communication	Low-dose aspirin (LDA) may improve reproductive success in women with chronic, low-grade inflammation.	28323989
Inflammation, Pregnancy loss	Altered Intercellular Communication	In women attempting conception with elevated hsCRP and prior pregnancy loss, LDA may increase clinical pregnancy and live birth rates compared with women without inflammation and reduce hsCRP elevation during pregnancy.	28323989
Inflammation	Altered Intercellular Communication	The expression of genes specific for T1D inflammation was associated with the abundance of specific bacteria in the duodenum.	28324102
Inflammation, Carcinogenesis, Malignant Neoplasms	Altered Intercellular Communication	Interaction between inflammation, immunity and carcinogenesis occurs in different cancers; however, the potential roles of different molecules involved in these processes in relation to ovarian carcinogenesis were not fully investigated.	28325363
Inflammation	Altered Intercellular Communication	In addition, GG genotype of IL4RA rs8832 was associated with type-2 endotype, whereas A allele of ADAM33 T_2 was associated with mixed type of eosinophilic/type-2 and neutrophilic inflammations.	28326636
ARCN1 gene	Altered Intercellular Communication	These unique data indicate that the current model for airway wall inflammation in COPD is oversimplified, and contrast with innate inflammatory activation in the lumen, at least in mild-moderate disease.	28326668
Inflammation, Chronic pain	Altered Intercellular Communication	We sought to investigate the relationship between inflammation and chronic pain in PLWH.	28328552
Inflammatory abnormality of the eye	Altered Intercellular Communication	Over 1 month, an 81-year-old man developed progressive left periocular inflammation unresponsive to treatment.	28328558
Angiectasis, Inflammation, Thrombosis, Hemorrhage, Necrosis	Altered Intercellular Communication	Conjunctival biopsy showed acute inflammation with necrosis, vascular ectasia with thrombosis and hemorrhage.	28328595
Inflammation	Altered Intercellular Communication	Only in patients with a confirmed eGFR less than 60 ml/min per 1.73 m at inclusion, a higher soluble-CIADIS weighted score (increased inflammation) was associated with a steeper decrease of renal function of -2.3 (ml/min per 1.73 m) per year (95% CI -3.6 to -1.0).	28328797
Inflammation, Fever, CTCAE, Thromboembolism	Altered Intercellular Communication	Eculizumab allowed the resolution of fever and inflammation, and prevented further thromboembolism.	28328837
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Thromboses, as observed in our case, may be associated with fever and marked inflammation.	28328837
Myocarditis, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Tissue characterization by T1 and T2 mapping cardiovascular magnetic resonance imaging to monitor myocardial inflammation in healing myocarditis.	28329275
Myocarditis, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	This study evaluated the ability of T1 and T2 mapping cardiovascular magnetic resonance (CMR) to monitor the course of myocardial inflammation in healing myocarditis.	28329275
deficiency aspects, Inflammation, physiopathological, Neoplasms	Altered Intercellular Communication	Sleep deficiency is linked to metabolic dysfunction and chronic inflammation, which may contribute to higher mortality from cardiometabolic conditions and promote tumor progression.	28329353
Inflammation, Necrosis	Altered Intercellular Communication	A skin biopsy revealedgranulomatous inflammation in the deep dermisand the subcutaneous fat with foci of necrosis.Within the foci of necrosis were large histiocytoidstructures with prominent nuclei.	28329521
Inflammation, Swelling, FBN1 gene, Facial paralysis	Altered Intercellular Communication	A 56-year-old male patient with Marfan syndrome presented with swelling and inflammation of the left parotid gland associated with progressively complete facial nerve paralysis.	28330578
Inflammation, Squamous metaplasia, Necrosis	Altered Intercellular Communication	The histological examination of a biopsy showed a lobulocentric process with necrosis, squamous metaplasia, and inflammation.	28330578
Inflammation, Brain Diseases, Cognition Disorders, Neuronal loss in central nervous system	Altered Intercellular Communication	TMEM106B risk variants are associated with inflammation, neuronal loss, and cognitive deficits, even in the absence of known brain disease, and their impact is highly selective for the frontal cerebral cortex of older individuals (>65 years).	28330615
Inflammation, Dyslipidemias, Dysglycemia, Hypertension, CTCAE	Altered Intercellular Communication	MESA study participants with higher pericardial and hepatic fat were more likely to be older, were more frequently men, and had a higher prevalence of cardiometabolic risk factors (including dysglycemia, dyslipidemia, hypertension), as well as adiposity-associated inflammation.	28330662
Inflammation, Acute Kidney Tubular Necrosis, Fibrosis Assessment	Altered Intercellular Communication	In contrast, expression of the NTT-MMP-2 isoform resulted in a dramatic increase in tubular cell necrosis, inflammation, and fibrosis.	28331061
ARCN1 gene, Deficiency of butyryl-CoA dehydrogenase, Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Patients with SCAD and concomitant COPD are at high risk of cardiovascular adverse events, due to chronic inflammation, responsible of endothelial dysfunction, oxidative stress and heightened platelet reactivity (PR).	28331925
Chronic Kidney Diseases	Altered Intercellular Communication	Elevated intact parathyroid hormone (iPTH) levels can contribute to morbidity and mortality in children with chronic kidney disease (CKD).	28332096
Parkinson Disease, Impaired cognition	Altered Intercellular Communication	Phenotype of postural instability/gait difficulty in Parkinson disease: relevance to cognitive impairment and mechanism relating pathological proteins and neurotransmitters.	28332604
Impaired cognition	Altered Intercellular Communication	The relationships between motor phenotypes and cognitive impairment and the underlying mechanisms relating pathological proteins and neurotransmitters in cerebrospinal fluid (CSF) are unknown.	28332604
Inflammation, Periodontitis	Altered Intercellular Communication	Additionally, whether this association was independent of periodontitis, and a systemic marker of inflammation, serum C-reactive protein (CRP) was examined.	28332718
Airway structure, Asthma	Altered Intercellular Communication	In addition, age at asthma onset appears to influence airway inflammation in patients with CAL.	28332897
Parkinson Disease, Inflammation	Altered Intercellular Communication	The study suggested that there may be a reduced capacity for the IgG to inhibit Fcg-RIIIa binding, which would allow an increased ability for the IgG to cause antibody-dependent cell cytotoxicity and a possible state of low-grade inflammation in individuals with Parkinson's disease.	28334832
Inflammation, Gait impairment	Altered Intercellular Communication	A 68-year-old Hispanic female with a previous history of bilateral knee arthroplasty presented with acute right-knee inflammation and gait impairment.	28335753
Inflammation, Traumatic injury, Allergy - Charge Type Reason	Altered Intercellular Communication	Acquired limbal stem cell deficiency (LSCD) describes a condition in which the corneal limbal stem cells are altered or destroyed, typically due to ocular trauma, chronic allergy or inflammation.	28336223
Inflammation, Chronic disease	Altered Intercellular Communication	Serum high-sensitivity CRP is a marker of inflammation and an independent predictor of chronic diseases.	28336391
Inflammation	Altered Intercellular Communication	Remnant particles accumulate in the arterial wall, potentially propagating local and systemic inflammation.	28336558
Inflammation, Dysautonomia, Familial, Hyperlipoproteinemia Type III	Altered Intercellular Communication	We evaluated the impact of remnant cholesterol on arterial wall inflammation, circulating monocytes, and bone marrow in patients with familial dysbetalipoproteinemia (FD).	28336558
Inflammation	Altered Intercellular Communication	Arterial wall inflammation and bone marrow activity were measured using 18F-FDG PET/CT.	28336558
Inflammation, Dysautonomia, Familial	Altered Intercellular Communication	Patients with FD have increased arterial wall and cellular inflammation.	28336558
Communicable Diseases, Pneumonitis	Altered Intercellular Communication	Specific depletion of neutrophils in vivo using a mAb and simultaneous infection with HMPV exhibited higher levels of inflammatory cytokines, pulmonary inflammation, and severe clinical disease compared with HMPV-infected, competent mice.	28336678
Communicable Diseases, Pneumonitis	Altered Intercellular Communication	The absence of gd T cells during HMPV infection led to reduced pulmonary inflammation.	28336678
Inflammation	Altered Intercellular Communication	ER has been shown to be beneficial in disease prevention and it reduces chronic inflammation.	28337029
Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	Chronic inflammation significantly contributes to the pathogenesis of several neurodegenerative disorders.	28337659
Neurodegenerative Disorders, Inflammation, MS gene	Altered Intercellular Communication	Similar results have also been demonstrated in patients of multiple sclerosis (MS), a neurodegenerative disease characterized by persisting inflammation.	28337659
Inflammation	Altered Intercellular Communication	The dysregulation of the A20 pathway could then contribute to the persistence of inflammation in these disorders.	28337659
Delirium, Cognitive problems	Altered Intercellular Communication	Long-Term Self-Reported Cognitive Problems After Delirium in the Intensive Care Unit and the Effect of Systemic Inflammation.	28338222
Delirium, Inflammation, Cognitive problems	Altered Intercellular Communication	To describe the association between intensive care unit (ICU) delirium and self-reported cognitive problems in 1-year ICU survivors, and investigate whether this association was altered by exposure to systemic inflammation during ICU stay.	28338222
Delirium, Inflammation	Altered Intercellular Communication	The cumulative exposure to systemic inflammation did not alter this association, suggesting that delirium in the context of little inflammation is also detrimental.	28338222
Inflammation, Cystitis, Bladder pain	Altered Intercellular Communication	However, absolute cessation of ketamine is the key to success in KC treatment.Key words: Ketamine-induced cystitis, augmentation enterocystoplasty, bladder pain, contracted bladder, inflammation, surgery.	28339443
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Telomere Length, Oxidative Stress, Inflammation and BDNF Levels in Siblings of Patients with Bipolar Disorder: Implications for Accelerated Cellular Aging.	28339618
Inflammation, Pain Distress Question	Altered Intercellular Communication	Associations were not attenuated with adjustment for systemic inflammation or pain.	28340012
Refractory anemias, Inflammation	Altered Intercellular Communication	mtDNA in RA SF was correlated with systemic inflammation as assessed by CRP concentrations.	28340056
Granulomatous inflammation, Myositis	Altered Intercellular Communication	Three cases of inflammatory myopathy with abundant macrophages (IMAM), 8 cases of granulomatous inflammation and 23 other deltoid muscle biopsies used as controls were all negative.	28340105
Pharyngeal Carcinoma, Inflammation	Altered Intercellular Communication	Diet and inflammation have been suggested to be important risk factors for oral and pharyngeal cancer.	28340515
Inflammation, Asthma	Altered Intercellular Communication	Association of systemic inflammation, adiposity, and metabolic dysregulation with asthma burden among Hispanic adults.	28340865
Inflammation, Obesity	Altered Intercellular Communication	Adiposity, metabolic dysregulation, and inflammation are all implicated in pathogenesis of obesity-related asthma, but their independent contributions are poorly understood.	28340865
Symptoms, Inflammation, No metabolic abnormalities	Altered Intercellular Communication	To examine the independent contributions of body fat distribution, metabolic abnormalities and inflammation on asthma symptoms and pulmonary function among Hispanics.	28340865
Hemorrhage	Altered Intercellular Communication	Indications for conversion included severe inflammation/adhesion (n = 31, 46.3%), difficult anatomy (n = 14, 20.9%) and bleeding (n = 6, 9.0%).	28340928
Hepatitis C, Hepatitis, FAM126A gene	Altered Intercellular Communication	The HCC risk increases with the severity of liver inflammation, and the clinical course of HCV infection depends on a balance between pro- and anti-inflammatory cytokines.	28340949
Inflammation, Lymphohistiocytosis, Hemophagocytic, Post-transplant lymphoproliferative disorder	Altered Intercellular Communication	Anti-CD20-based chemo-immunotherapeutic regimens have been suggested to assist in the management of Epstein-Barr virus (EBV)-induced hemophagocytic lymphohistiocytosis (HLH) and EBV-associated post-transplant lymphoproliferative disorders (EBV-PTLD), by reducing EBV viral load and EBV-induced inflammation.	28340951
Airway structure, Respiratory Hypersensitivity, Eosinophilic inflammation	Altered Intercellular Communication	Asthma is the chronic inflammation of airways characterized by eosinophilic infiltration, mucus overproduction, airway hyper-responsiveness and airway remodeling.	28341820
Post-Traumatic Stress Disorder	Altered Intercellular Communication	Exploring the Link Between Posttraumatic Stress Disorder and inflammation-Related Medical Conditions: An Epidemiological Examination.	28342139
Post-Traumatic Stress Disorder	Altered Intercellular Communication	These findings suggest a complex link between PTSD and inflammation-related medical conditions.	28342139
Pancreatitis, Acute, Inflammation	Altered Intercellular Communication	The expression and activation of the AIM2 inflammasome correlates with inflammation and disease severity in patients with acute pancreatitis.	28342645
Single organ dysfunction, Inflammation, Pancreatitis	Altered Intercellular Communication	Our data demonstrates that AIM2 inflammasome expression and activation is increased early during the course of acute pancreatitis, and suggests that AIM2 activation may affect systemic inflammation and organ failure in these patients.	28342645
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Nutritional interventions aimed at reducing inflammation (INF) may contribute to reduced cancer recurrence risk, but studies have been limited to animal models.	28342988
Inflammation	Altered Intercellular Communication	Furthermore, their expression of FcRL4 and their enrichment in the IgA isotype points towards a potential role for these cells in the link between mucosal and joint inflammation.	28343748
Dilated Cardiomyopathy Pathway, Myocarditis, Hypertrophy	Altered Intercellular Communication	Neural cell adhesion molecule expression in dilated cardiomyopathy is associated with intramyocardial inflammation and hypertrophy.	28343767
Doctor of Chiropractic, Dilated Cardiomyopathy Pathway	Altered Intercellular Communication	Chronic intramyocardial inflammation (inflammatory cardiomyopathy/DCMi) is linked to the pathogenesis of dilated cardiomyopathy (DCM).	28343767
Inflammation, Venous Thromboembolism, Thrombophilia, Endothelial dysfunction, vinyltriethoxysilane	Altered Intercellular Communication	Polyunsaturated fatty acids (PUFAs) take part in various biological events linked to the pathogenesis of venous thromboembolism (VTE), including inflammation, endothelial dysfunction, and hypercoagulability.	28344195
Inflammation, Liver Cirrhosis	Altered Intercellular Communication	Inflammation plays a vital role in liver cirrhosis progression and prognosis.	28345155
Primary malignant neoplasm	Altered Intercellular Communication	The Dietary Inflammatory Index (DII)TM, which was developed to characterize the inflammatory potential of a person's diet, has been shown to be associated with inflammatory conditions such as cancer.	28345504
Inflammation	Altered Intercellular Communication	We found that old monkeys have greater systemic inflammation and poor intestinal barrier function as compared to young monkeys.	28346561
Inflammatory disorder, Acute appendicitis NOS (disorder), Ulcerative Colitis, Pelvic Inflammatory Disease	Altered Intercellular Communication	Patrinia scabiosifolia Link (PS), a member of the Patrinia genus (Caprifoliaceae family), has traditionally been used in folk medicines to treat various inflammatory diseases such as acute appendicitis, ulcerative colitis, and pelvic inflammation in Korea and other parts of East Asia.	28347830
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Chronic inflammation associates with increased senescence, which is a strong predictor for cardiovascular disease.	28347991
Inflammation, Cardiovascular Diseases, Gout	Altered Intercellular Communication	We hypothesised that inflammation accelerates senescence and thereby enhances the risk of cardiovascular disease in gout.	28347991
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Alcohol and red wine consumption, but not fruit, vegetables, fish or dairy products, are associated with less endothelial dysfunction and less low-grade inflammation: the Hoorn Study.	28349255
Inflammation, Endothelial dysfunction, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Endothelial dysfunction and low-grade inflammation are key phenomena in the pathobiology of cardiovascular disease (CVD).	28349255
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	We investigated the associations between the above food groups and endothelial dysfunction and low-grade inflammation in a population-based cohort of Dutch elderly individuals.	28349255
Inflammation	Altered Intercellular Communication	Only red wine consumption was associated with a lower low-grade inflammation biomarker score [-0.18 (-0.33; -0.04)].	28349255
Inflammation, Dyslipidemias, Myocardial Ischemia, Diabetes Mellitus, Hypertension, CTCAE	Altered Intercellular Communication	Age 62 (range 56-66) cardiometabolic outcomes included hypertension, diabetes, dyslipidemia, inflammation, and ischemic heart disease.	28349665
Inflammation, Hypertension, CTCAE, Dyslipidemias, Diabetes Mellitus	Altered Intercellular Communication	Accelerated (quadratic) BMI slope was significantly associated with greater risk for hypertension, diabetes, dyslipidemia, and inflammation; odds ratios ranged from 1.93 (diabetes) to 3.15 (dyslipidemia).	28349665
Inflammation, Colorectal Carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Chronic inflammation increases the risk of development of various cancers, including colorectal cancer.	28349833
Inflammation, Colorectal Neoplasms, Colorectal Carcinoma	Altered Intercellular Communication	Interleukin-6 has been described as a key regulator of colorectal cancer development and is important in the process of colorectal tumorigenesis largely through the regulation of tumor-promoting inflammation.	28349833
Inflammation	Altered Intercellular Communication	Systemic inflammation is increased in patients who develop ICU-acquired weakness compared with patients who do not develop ICU-acquired weakness in the first 4 days after ICU admission.	28350642
Achalasia, Inflammation, Weight decreased, Ulcer	Altered Intercellular Communication	Severe inflammation, ulcers, achalasia, and neoplasias were considered clinically significant endoscopic findings (CSEF) that could explain weight loss.	28350752
Sepsis, Inflammation, Obstruction of biliary tree, Neoplasms	Altered Intercellular Communication	The aetiology of the neuroendocrine tumors is unclear; in most cases, inflammation of the bile ducts may be the underlying cause and for this reason, the initial patient's evaluation should be focused on the different aspects concerning the oncological one and the possible sequelae of the biliary obstructions that can evolve in biliary sepsis.	28350976
Adenocarcinoma of prostate, Benign prostatic hypertrophy	Altered Intercellular Communication	Dying for love: Perimenopausal degeneration of vaginal microbiome drives the chronic inflammation-malignant transformation of benign prostatic hyperplasia to prostatic adenocarcinoma.	28351489
Inflammation, Prostate carcinoma, Benign prostatic hypertrophy	Altered Intercellular Communication	The recent demonstration that far from being benign, "benign" prostatic hypertrophy is a likely a reaction of the prostate to chronic untreated lower genital tract infection, and that this chronic inflammation is likely the usual precursor to the frequent occurrence of prostatic carcinoma has far reaching implications.	28351489
Inflammation, Malignant neoplasm of prostate	Altered Intercellular Communication	Hence the major hypothesis is that prostatic cancer may arise due to chronic infection and inflammation in the prostate gland consequent upon the altered microbiome of the menopausal female genital tract.	28351489
Painful intercourse female, Inflammation	Altered Intercellular Communication	It suggests that male dyspareunia, although almost never encountered in clinical practice may in fact be relatively common in older males, and in particular if diagnosed, represents a critical opportunity for therapeutic intervention to interrupt the chronic inflammation - cancer transformation and progression which has been well documented in other tissues.	28351489
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Numerous studies have found that risk of cardiovascular diseases is associated with increased blood levels of circulating markers of systemic inflammation.	28351806
Unknown (origin) (qualifier value)	Altered Intercellular Communication	Clinical information and histology were reviewed and cases were classified into three groups: Group 1: IgG4-RD orbital inflammation (n=43); Group 2: idiopathic OID (n=12) and Group 3: autoimmune OID (n=14).	28351925
Unknown (origin) (qualifier value)	Altered Intercellular Communication	Significant elevations of serum IgG2 and tissue IgG2 plasma cells are present in orbital IgG4-RD in comparison with non-IgG4 orbital inflammation (idiopathic and autoimmune OID), suggesting that IgG2 may play a role in IgG4-RD.	28351925
Communicable Diseases, Eosinophilic peritonitis, Inflammation, Irritation	Altered Intercellular Communication	Eosinophilic peritonitis in a continuous ambulatory peritoneal dialysis patient: Inflammation and irritation without infection.	28352028
ARCN1 gene, Inflammation	Altered Intercellular Communication	Positive correlation of airway resistance and serum asymmetric dimethylarginine level in COPD patients with systemic markers of low-grade inflammation.	28352168
ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure	Altered Intercellular Communication	The major feature of COPD is a progressive airflow limitation caused by chronic airway inflammation and consequent airway remodeling.	28352168
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Modified arginase and nitric oxide synthase (NOS) pathways are presumed to contribute to the inflammation and fibrosis.	28352168
ARCN1 gene, Inflammation	Altered Intercellular Communication	Positive correlation of Raw with ADMA in COPD patients showing evidence of a systemic low-grade inflammation implies that ADMA contributes to the progression of COPD, probably by shunting L-arginine from the NOS pathway to the arginase one.	28352168
TNF protein, human, Inflammation	Altered Intercellular Communication	VP patients had a systemic inflammation response involving IL-6, TNF-a, and MCP-1 which may be due to virus-induced activation of macrophages.	28352642
hepcidin	Altered Intercellular Communication	HFR achieved a greater reduction in Hepcidin-25 levels than both LFBD [-72% (95% CI: -11 to -133), p = 0.022] and HFBD [-137% (95% CI: -2 to -272), p = 0.047], conceivably due to both a greater removal (because of its convective/adsorptive component) and a lower inflammation-related Hepcidin-25 production.	28353202
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Furthermore, endothelial dysfunction appears inversely related to the degree of inflammation in HIV+ patients as measured by IL-6.	28353539
ANOPHTHALMIA AND PULMONARY HYPOPLASIA, Pancreatic carcinoma	Altered Intercellular Communication	Different inflammation-based scores such as the neutrophil/lymphocyte ratio (NLR), the Odonera Prognostic Nutritional Index (PNI), the Glasgow Prognostic Score, the platelet/lymphocyte ratio, and the C-reactive protein/albumin ratio have been found to be significantly associated with pancreatic cancer (PDAC) prognosis.	28353661
Inflammation, Bacterial Infections	Altered Intercellular Communication	Recently, a number of diseases were found to be attributed to bacterial infections, resulting in low-grade inflammation and progressive matrix disturbance.	28355086
Bone necrosis, Myositis	Altered Intercellular Communication	In addition to displaying muscle inflammation, STIR-WBMRI can efficiently detect early multifocal osteonecrosis in the whole bodies of patients with PM/DM.	28355130
Inflammation, Damage, Chronic Kidney Diseases	Altered Intercellular Communication	Especially in the early phase, CKD is associated with silently ongoing renal damage and inflammation.	28355260
Liver carcinoma	Altered Intercellular Communication	Inflammation scores predict the survival of patients with hepatocellular carcinoma who were treated with transarterial chemoembolization and recombinant human type-5 adenovirus H101.	28355305
FAM126A gene	Altered Intercellular Communication	The NLR-PLR score is a more powerful predictive system than the other inflammation-based scores for patients with HCC who were treated with TACE and H101.	28355305
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Accumulating evidence links inflammation and atrial fibrillation (AF).	28355442
Inflammation	Altered Intercellular Communication	To assess whether markers of systemic and atrial inflammation are associated with incident AF in the general population.	28355442
Inflammation, Chronic disease	Altered Intercellular Communication	It is assumed that both social stress and chronological age increase the risk of chronic illness, in part, through their effect on systemic inflammation.	28356188
Inflammation	Altered Intercellular Communication	Limited Presence of IL-22 Binding Protein, a Natural IL-22 Inhibitor, Strengthens Psoriatic Skin Inflammation.	28356382
Inflammation	Altered Intercellular Communication	Among them, IL-22 largely contributes to epithelial remodeling and inflammation through inhibiting the terminal differentiation of keratinocytes and inducing antimicrobial peptides and selected chemokines.	28356382
Inflammation, Inflammatory disorder	Altered Intercellular Communication	In chronic inflammatory disorders, unabated inflammation has been associated with a break in innate immune tolerance to self-DNA.	28356384
Cessation of life, Inflammation	Altered Intercellular Communication	IL-26 expressed in inflammatory lesions confers proinflammatory properties to DNA released by dying cells, setting up a positive amplification loop between extensive cell death and unabated inflammation.	28356384
Inflammation, Depression, CTCAE, Bipolar Disorder	Altered Intercellular Communication	Background: Low-grade chronic inflammation, which can be modulated by diet, has been suggested as an important risk factor for depression, but few studies have investigated the association between the inflammatory potential of the diet and depression.Objective: We investigated the prospective association between the inflammatory potential of the diet, measured by the Dietary Inflammatory Index (DII), and incident depressive symptoms and tested the potential modulating effect of sex, age, physical activity, and smoking status.Methods: This study included 3523 participants (aged 35-60 y) from the SU.VI.MAX (Supplementation en Vitamines et Mineraux Antioxydants) cohort, who were initially free of depressive symptoms.	28356432
Inflammation, Tissue injury	Altered Intercellular Communication	The resolution of inflammation is an active process orchestrated by specialized proresolving lipid mediators (SPM) that limit the host response within the affected tissue; failure of effective resolution may lead to tissue injury.	28356517
Inflammatory Bowel Diseases, CDISC Integrated Basic Data Structure Dataset, SCAPULOPERONEAL MYOPATHY, X-LINKED DOMINANT, Gastrointestinal inflammation	Altered Intercellular Communication	Because persistence of inflammatory signals is a main feature of chronic inflammatory conditions, including inflammatory bowel diseases (IBDs), herein we investigate expression and functions of SPM in intestinal inflammation.	28356517
Colitis	Altered Intercellular Communication	Systemic treatment with protectin (PD)1n-3 DPA or resolvin (Rv)D5n-3 DPA protected against colitis and intestinal ischemia/reperfusion-induced inflammation in mice.	28356517
Gastrointestinal inflammation, Colitis	Altered Intercellular Communication	Inhibition of 15-lipoxygenase activity reduced PD1n-3 DPA and augmented intestinal inflammation in experimental colitis.	28356517
Inflammatory Bowel Diseases, CDISC Integrated Basic Data Structure Dataset, SCAPULOPERONEAL MYOPATHY, X-LINKED DOMINANT, Gastrointestinal inflammation	Altered Intercellular Communication	Because persistence of inflammatory signals is a main feature of chronic inflammatory conditions, including inflammatory bowel diseases (IBDs), herein we investigate expression and functions of SPM in intestinal inflammation.	28356517
Inflammatory Bowel Diseases, CDISC Integrated Basic Data Structure Dataset, SCAPULOPERONEAL MYOPATHY, X-LINKED DOMINANT, Gastrointestinal inflammation	Altered Intercellular Communication	Because persistence of inflammatory signals is a main feature of chronic inflammatory conditions, including inflammatory bowel diseases (IBDs), herein we investigate expression and functions of SPM in intestinal inflammation.	28356517
ARCN1 gene, Inflammation, Hypertriglyceridemia	Altered Intercellular Communication	The data from the present study showed that the serum levels of PAI-1 are higher in patients with COPD and that moderate-to-severe airflow limitation, hypertriglyceridemia, and systemic inflammation are independent predictors of an elevated PAI-1 level.	28356730
Cardiac Hypertrophy, Fibrosis Assessment, Inflammation, Heart failure	Altered Intercellular Communication	Wnt signaling is dysregulated in heart failure (HF) and may promote cardiac hypertrophy, fibrosis, and inflammation.	28357477
Fibrosis Assessment, Myocarditis	Altered Intercellular Communication	Wnt5a induces IL-6 and TIMP-1 in cardiac fibroblasts, which might promote myocardial inflammation and fibrosis, and thereby contribute to HF progression.	28357477
Fibrosis Assessment, Myocarditis	Altered Intercellular Communication	* Wnt5a-mediated effects might promote myocardial inflammation and fibrosis, and thereby contribute to HF progression.	28357477
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Histopathological analysis revealed malignancy in three cases, non-specific inflammation in two cases, and normal bone in two cases.	28357575
Inflammation, Obstruction, Traumatic injury, Irritation	Altered Intercellular Communication	Vallecular cysts are formed when the duct of a mucous gland or lingual tonsillar crypt is dilated owing to obstruction from inflammation, irritation, or trauma.	28357610
Inflammation, Pneumonia	Altered Intercellular Communication	Pneumonia and inflammation in acute decompensated heart failure: a registry-based analysis of 1939 patients.	28357890
Inflammation, Pneumonia	Altered Intercellular Communication	The prognostic impact of pneumonia and signs of systemic inflammation in patients with acute decompensated heart failure (ADHF) has not been fully elucidated yet.	28357890
Inflammation, Pneumonia	Altered Intercellular Communication	The aim of the present study was thus to investigate the association of pneumonia and the inflammation surrogate C-reactive protein with all-cause mortality in patients admitted for ADHF.	28357890
Inflammation, Pneumonia	Altered Intercellular Communication	However, inflammation in general seems to be more important than pneumonia itself for long-term prognosis.	28357890
Inflammation	Altered Intercellular Communication	Simple and cheap anthropometric indices such as BAI and WHR may be better predictors of low-grade inflammation than VAI in elderly women with SO.	28358295
Sepsis, Inflammation	Altered Intercellular Communication	In particular, Gram-negative bacilli (GNB), which induce significant inflammation and consequent multiple organ failure, are the etiological bacterial agent in 40% of severe sepsis cases.	28358803
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	Impact of systemic inflammation on gastric cancer outcomes.	28358923
Inflammatory abnormality of the eye, Visual disturbance	Altered Intercellular Communication	Ocular inflammation is occasionally observed after vaccinations, and most of them resolve without permanent visual disturbances.	28358967
palladium, Inflammation, Peyronie Disease	Altered Intercellular Communication	Inflammation is mechanistically involved in the development of Peyronie's disease (PD).	28359407
palladium, Inflammation	Altered Intercellular Communication	IL-6 trans-signaling and PTX3 amplification at the site of inflammation could have a role in pathophysiological mechanisms of PD.	28359407
Inflammation, Congestive heart failure	Altered Intercellular Communication	As inflammation plays a crucial role in the complex pathophysiology of CHF, we hypothesized that suPAR might be a suitable prognostic biomarker in patients with CHF.	28359415
Inflammation, Chronic disease	Altered Intercellular Communication	Albumin level is regulated by nutritional intake and inflammation due to chronic disease, which make it a useful part of a preoperative frailty assessment.	28359793
Hypernatremia, Inflammation, Fibrosis Assessment, Cardiac dysfunction, Aortic Valve Stenosis	Altered Intercellular Communication	Aortic stenosis (AS) is characterized by pressure overload and causes left ventricular (LV) fibrosis and inflammation, two mechanisms that eventually lead to cardiac dysfunction.	28360193
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Gal-3 directly correlated with parameters assessing myocardial fibrosis and inflammation in AS patients.	28360193
Myocardial fibrosis, Inflammation	Altered Intercellular Communication	AS animals presented enhanced cardiac Gal-3 expression, which paralleled higher myocardial fibrosis and inflammation.	28360193
Inflammation, Cardiac fibrosis	Altered Intercellular Communication	In short-term AS, the increase in myocardial Gal-3 expression was associated with cardiac fibrosis and inflammation, alterations that were prevented by Gal-3 blockade.	28360193
Inflammation, Arteriosclerosis	Altered Intercellular Communication	We retrospectively analyzed 33 biomarkers from different pathophysiological domains (inflammation, oxidative stress, remodeling, cardiac stretch, angiogenesis, arteriosclerosis, and renal function) in 460 HF patients (21% HFpEF, left ventricular ejection fraction >=45%) measured at discharge after hospitalization for acute HF.	28360225
Inflammation	Altered Intercellular Communication	Linear regression followed by network analyses revealed prominent inflammation and angiogenesis-associated interactions in HFpEF and mainly cardiac stretch-associated interactions in HFrEF.	28360225
Inflammation	Altered Intercellular Communication	In HFpEF, inflammation and angiogenesis-mediated interactions are predominantly observed, while stretch-mediated interactions are found in HFrEF.	28360225
Inflammation	Altered Intercellular Communication	Erythrocyte concentrations of B1, B2, B6 but not plasma C and E are reliable indicators of nutrition status in the presence of systemic inflammation.	28361748
Inflammation, Malnutrition	Altered Intercellular Communication	Malnutrition is a strong predictor of mortality on hemodialysis patients, especially when it is associated with inflammation.	28361749
Inflammation, Malnutrition	Altered Intercellular Communication	Malnutrition Inflammation Score (MIS) is a simple and low cost tool which assesses the presence of malnutrition associated with inflammation.	28361749
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Systemic inflammation and family history in relation to the prevalence of type 2 diabetes based on an alternating decision tree.	28361994
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus	Altered Intercellular Communication	Our study demonstrates that systemic inflammation was proportionally associated with increased prevalence of type 2 diabetes even after adjusting for body mass index, especially in subjects without a family history of diabetes.	28361994
Inflammatory abnormality of the eye	Altered Intercellular Communication	Plasmapheresis and IVIg may be life-saving and contribute to reduce ocular surface inflammation in TEN.	28362052
Vasculitis, Coronary Artery Disease, Rheumatism	Altered Intercellular Communication	Inflammatory rheumatic diseases (IRD) are associated with accelerated coronary artery disease (CAD), which may result from both systemic and vascular wall inflammation.	28362874
Inflammation	Altered Intercellular Communication	Nuclear factor-kappa B (NF-kB) induces the production of inflammatory cytokines and adhesion molecules, which play an essential role in angiogenesis and inflammation.	28362919
Inflammation, Asthma, Wheezing	Altered Intercellular Communication	Inflammation pathway of asthma and recurrent wheeze are related to eosinophil cells in older children and neutrophil cells in younger children.	28363401
Inflammation	Altered Intercellular Communication	Systemic inflammation is associated with survival after second-line mTT.	28363437
Dual-probe in Situ Hybridization, Hyperostosis, Diffuse Idiopathic Skeletal, Calcinosis, Osteogenesis	Altered Intercellular Communication	Diffuse idiopathic skeletal hyperostosis (DISH) is a non-inflammatory condition that involves calcification and ossification of the spinal ligaments and entheses.	28364275
Inflammation	Altered Intercellular Communication	Ubiquitin-specific protease 14 regulates LPS-induced inflammation by increasing ERK1/2 phosphorylation and NF-kB activation.	28364380
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	To determine whether interdependence in couples' sleep (sleep-wake concordance i.e., whether couples are awake or asleep at the same time throughout the night) is associated with two markers of cardiovascular disease (CVD) risk, ambulatory blood pressure (BP) and systemic inflammation.	28364457
Inflammation, Sleep Apnea, CTCAE	Altered Intercellular Communication	Objective, but Not Subjective, Sleepiness is Associated With Inflammation in Sleep Apnea.	28364485
Inflammation, Disease, Osage language	Altered Intercellular Communication	Our findings suggest that OSA with objective EDS is the more severe phenotype of the disorder associated with low-grade inflammation, a link to cardiometabolic morbidity and mortality.	28364485
Communicable Diseases, Inflammation, Bronchiolitis	Altered Intercellular Communication	Secondary outcomes included overall survival, prevalence of acute rejection, lymphocytic bronchiolitis and infection, lung function, pulmonary and systemic inflammation, and bone mineral density.	28365177
Orofacial neuropathic pain, Pain Distress Question	Altered Intercellular Communication	41 patients (73%) of orofacial neuropathic pain patients had a history of pain compatible with an inflammatory condition; 4% (n=2) did not report any prior pain and 23% (n=13) could not remember.	28365394
Degenerative polyarthritis	Altered Intercellular Communication	Validation of a Knowledge Transfer Tool for the Knee Inflammation MRI Scoring System for Bone Marrow Lesions According to the OMERACT Filter: Data from the Osteoarthritis Initiative.	28365581
Inflammation, Arthritis	Altered Intercellular Communication	The Relationship Between Cardiac Conduction Times, Cardiovascular Risk Factors, and Inflammation in Patients with Early Arthritis.	28365582
Inflammation, Arthritis, Conduction disorder of the heart	Altered Intercellular Communication	To investigate the prevalence of conduction disorders in patients with early arthritis and the relationship with inflammation and traditional cardiovascular (CV) risk factors.	28365582
Inflammation, Arthritis, Conduction disorder of the heart	Altered Intercellular Communication	The prevalence of conduction disorders in patients with early arthritis was 12.5%, which is similar to the general population and was not associated with changes in inflammation markers.	28365582
Inflammation, Spanish Language, Spondylarthritis	Altered Intercellular Communication	Spondyloarthritis (SpA) is characterized by inflammation and new bone formation and can be treated by inhibition of the proinflammatory cytokines TNF-a and IL-17A.	28365787
Vitreous Hemorrhage, Inflammation	Altered Intercellular Communication	After treatment, the inflammation subsided but it took 3 months for the vitreous hemorrhage to totally resorb.	28365853
Inflammation, Chronic Kidney Diseases, Critical Illness, Kidney Diseases	Altered Intercellular Communication	GLP-1 plasma levels were determined in 3 different patient cohorts: 1) critically ill patients admitted to our intensive care unit (n = 215); 2) patients with chronic kidney disease on hemodialysis (n = 173); and 3) a control group (no kidney disease, no acute inflammation, n = 105).	28366423
Inflammation, Malnutrition, Vascular calcification, Analysis, Chronic Kidney Diseases	Altered Intercellular Communication	Cross-sectional analysis with all men included the Malnutrition, Inflammation and Vascular Calcification cohort, which enrolled consecutive nondialyzed patients with CKD stages 3-5.	28366446
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The dual regulation of substance P-mediated inflammation via human synovial mast cells in rheumatoid arthritis.	28366675
Refractory anemias, Inflammation	Altered Intercellular Communication	On the other hand, SP activates MCs to induce inflammatory mediators, suggesting the dual regulation of SP-mediated inflammation by MCs in RA.	28366675
Inflammation, Cerebral Infarction, Acute Lung Injury, Hemorrhagic, Blood Coagulation Disorders	Altered Intercellular Communication	We determined whether serum MIF concentrations are associated with inflammation, severity, in-hospital major adverse events (IMAEs) (i.e., in-hospital mortality, acute lung injury, acute traumatic coagulopathy, progressive hemorrhagic injury and posttraumatic cerebral infarction) and long-term clinical outcome (i.e., 6-month functional outcome) after TBI.	28366792
Inflammation, Traumatic injury	Altered Intercellular Communication	Increased serum MIF concentrations have close relation to inflammation, trauma severity and clinical outcomes, substantializing MIF as a good prognostic biomarker after TBI.	28366792
Inflammation, Heart failure, Diabetes Mellitus	Altered Intercellular Communication	Inflammation plays an important role in heart failure and diabetes mellitus.	28367848
Inflammation, Pancreatitis, Endothelial dysfunction	Altered Intercellular Communication	In severe acute pancreatitis (SAP), systemic inflammation leads to endothelial dysfunction and activation of coagulation.	28368336
Postprandial Period, Endotoxemia, Cardiovascular Diseases	Altered Intercellular Communication	Postprandial inflammation and endotoxaemia are determinants of cardiovascular and metabolic disease risk which are amplified by high fat meals.	28368340
Postprandial Period, Endotoxemia	Altered Intercellular Communication	We aimed to examine the determinants of postprandial inflammation and endotoxaemia in older and younger adults following a high fat mixed meal.	28368340
Inflammatory Bowel Diseases, Tumor necrosis, Gastrointestinal inflammation	Altered Intercellular Communication	Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease.	28368383
Gastrointestinal inflammation, Colitis	Altered Intercellular Communication	In an animal model of anti-TNF-resistant intestinal inflammation, genetic deletion or pharmacological blockade of OSM significantly attenuates colitis.	28368383
Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis	Altered Intercellular Communication	Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are complex chronic inflammatory conditions of the gastrointestinal tract that are driven by perturbed cytokine pathways.	28368383
Inflammation, Biliary calculi	Altered Intercellular Communication	A total of 149 patients (120 female and 29 male) diagnosed with gallstones who underwent cholecystectomy and who did not have symptoms of acute inflammation were included.	28368860
Communicable Diseases, Inflammation, Calculi	Altered Intercellular Communication	The presence of gingival inflammation, calculus, and infectious dental diseases did not significantly differ between groups.	28369398
ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a corticosteroid-resistant airway inflammatory condition.	28369685
Immune thrombocytopenic purpura, Bronchiectasis, Granulomatous inflammation, Splenomegaly, Lymphadenopathy, Grade 1 Non-Infectious Wound Complication, CTCAE	Altered Intercellular Communication	The prevalence of non-infectious complications was similar to that of previously reported cohorts: bronchiectasis (35.8%), splenomegaly (22.4%), lymphadenopathy (26.3%), granulomatous inflammation (3.9%) and idiopathic thrombocytopenic purpura (14.5%).	28370285
Inflammation	Altered Intercellular Communication	The innate immune system, which includes toll-like receptor (TLR) signaling, plays an important role in inflammation and oncogenesis.	28370778
Inflammation, Bacteriuria	Altered Intercellular Communication	Asymptomatic bacteriuria is not a modifiable risk factor for chronic inflammation in the MHD population.	28370973
Inflammation, Joint Subluxations, Communicable Diseases, ACAA1 gene, Brain Concussion	Altered Intercellular Communication	Primary teeth with concussion or subluxation injury carry a low risk of PN and infection with periapical inflammation, root resorption, and PTL.	28371334
physiopathological	Altered Intercellular Communication	These results could explain some of the mechanisms of vascular dysfunction reported in inflammatory conditions.	28373136
Inflammation	Altered Intercellular Communication	In conclusion, IL-4 signaling plays a crucial role in the regulatory functions of SOCS1 in apoptosis and inflammation in human osteoarthritic chondrocytes.	28373981
Inflammation	Altered Intercellular Communication	Macrophages, chondrocytes, osteoblasts and osteoclasts express inducible NOS (iNOS) at the site of synovial inflammation.	28374504
Inflammation, White matter	Altered Intercellular Communication	PRDX2 was found to be upregulated in white matter MS lesions mainly in astrocytes, and its expression level was positively correlated with the degree of inflammation and oxidative stress.	28375164
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD) is a progressive disease with an inverse relationship between kidney function and levels of inflammation and oxidative stress.	28375641
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Further studies are needed to determine whether curcumin and B. serrata may be effective means to reduce inflammation in patients with CKD.	28375641
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Inflammation has been linked with development of some cancers.	28376082
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Prediagnostic systemic inflammation may impact colorectal cancer incidence and survival; therefore, prompting investigations linking inflammatory pathways preceding colorectal cancer with disease severity and progression.	28376082
Inflammation, Autonomic nervous system disorders, Atherosclerosis	Altered Intercellular Communication	The association between autonomic dysfunction, inflammation and atherosclerosis in men under investigation for carotid plaques.	28376102
Inflammation, Autonomic nervous system disorders, Atherosclerosis	Altered Intercellular Communication	In this study we hypothesized that autonomic dysfunction increases inflammation, which subsequently accelerates atherosclerosis.	28376102
Inflammation, Atherosclerosis	Altered Intercellular Communication	The aim of the current study was to investigate the association between autonomic tone, inflammation and atherosclerosis.	28376102
Inflammation, Atherosclerosis	Altered Intercellular Communication	To investigate if inflammation could provide a link between autonomic function and carotid atherosclerosis we adjusted the associations accordingly.	28376102
Inflammation, Dental Plaque, Atherosclerosis	Altered Intercellular Communication	After adjusting for WBCC and CRP the inverse association between BRS and carotid plaque area was attenuated and did not remain significant, while both WBCC and CRP remained significantly associated with carotid plaque area, indicating that low-grade inflammation can possibly link BRS to atherosclerosis.	28376102
Inflammation, Autonomic nervous system disorders, Atherosclerosis	Altered Intercellular Communication	We demonstrate that autonomic dysfunction is associated with atherosclerosis and that inflammation could play an important role in mediating this relationship.	28376102
Inflammation, Chronic sinusitis	Altered Intercellular Communication	Correlation of Symptoms, Clinical Signs, and Biomarkers of Inflammation in Postsurgical Chronic Rhinosinusitis.	28376637
Inflammation, Pain Distress Question	Altered Intercellular Communication	Mucosal inflammation identified on nasal endoscopy was positively correlated with congestion ( P < .028), runny nose ( P < .002), and ear pain ( P < .007).	28376637
Inflammation, Rhinorrhea, Craniosynostosis	Altered Intercellular Communication	Nasal endoscopy, not CT imaging, has the strongest correlation with the 2 cardinal symptoms of congestion and runny nose in CRS patients; these correlate with biomarkers of eosinophilic inflammation.	28376637
Hemangioma, Cavernous, Inflammation, Microbleeds, Malignant Neoplasms	Altered Intercellular Communication	We conclude that, although rare, rapid expansion of an existing cavernoma should be considered suspicious for the development of other malignant tumors, and propose adding chronic inflammation in the surrounding brain caused by microbleeds and hemosiderin deposition from the cavernoma to the list of possible causes.	28377258
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	CONCLUSIONS We postulate that PTX3 might be an early marker of CV mortality in patients with advanced CKD yet before the increase of specific marker for systemic inflammation like hsCRP.	28377558
Inflammation	Altered Intercellular Communication	The biopsy slides showed suppurative granulomatous inflammation affecting greater than 50% of the parenchymal lung surface.	28377567
Inflammation, Chronic disease	Altered Intercellular Communication	Apigenin can attenuate inflammation, which is associated with many chronic diseases of aging.	28378188
Inflammation, Injury of liver	Altered Intercellular Communication	Acute-phase inflammation plays a critical role in liver graft injury.	28378341
Inflammation, Injury of liver	Altered Intercellular Communication	Our data demonstrated that NLRP3 inflammasomes, activated by the RAP1/KC axis, played a critical role in initiating inflammation during the early stage of liver graft injury.	28378341
Inflammation, Venous Insufficiency	Altered Intercellular Communication	Objective Inflammation has been implicated as a factor that may contribute to chronic venous insufficiency.	28379059
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Inflammation plays a key role in the development and progression of OA both on the side of apoptosis and repair, while its exact role in pathogenesis has yet to be fully elucidated.	28379175
Inflammation, Damage, Hypertension, CTCAE	Altered Intercellular Communication	Hypertension is a chronic, low-grade inflammation process associated with the release of cytokines and development of target organ damage.	28380135
Shock, Inflammation	Altered Intercellular Communication	Heat shock proteins (HSPs) are molecular chaperones essential for maintaining cellular functions, but they can act as a danger signal during inflammation.	28380264
Have Autoimmune or Inflammatory Condition, Primary malignant neoplasm, Neoplasms, S100A4 protein, human	Altered Intercellular Communication	While chronic autoimmune inflammation is considered a potential risk factor for malignant transformation in many solid tumors, the opposite idea that cancer may trigger autoimmune responses remains controversial.	28381149
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	SUCNR1-mediated chemotaxis of macrophages aggravates obesity-induced inflammation and diabetes.	28382382
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Obesity induces macrophages to drive inflammation in adipose tissue, a crucial step towards the development of type 2 diabetes.	28382382
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	We therefore investigated whether succinate receptor 1 (SUCNR1) could play a role in the development of adipose tissue inflammation and type 2 diabetes.	28382382
Inflammation, Infiltration, Obesity	Altered Intercellular Communication	Our results reveal that activation of SUCNR1 in macrophages is important for both infiltration and inflammation of adipose tissue in obesity, and suggest that SUCNR1 is a promising therapeutic target in obesity-induced type 2 diabetes.	28382382
Inflammation, Mucopolysaccharidosis I	Altered Intercellular Communication	The elevated metabolites are predominantly lipid derivatives, and also include cysteine metabolites and a fibrinogen peptide fragment, consistent with the status of oxidative stress and inflammation in MPS III.	28382573
Smell Perception, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) is a common inflammatory condition and a major cause of olfactory loss.	28383208
Inflammation, Refractory anemias, Autoimmune Diseases, Rheumatoid Arthritis, Hyperplasia	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation and synovial hyperplasia, which usually affects multiple joints.	28383601
Colorectal Carcinoma	Altered Intercellular Communication	Less increased g-H2AX in UC-CRC compared to CRC gave evidence that colitis-triggered inflammation masks DNA damage, thus contributing to neoplastic transformation.	28383667
Inflammation, Carcinogenesis	Altered Intercellular Communication	We hypothesize that JNK-dependent cell cycle arrest is important in AUC, while chronic inflammation causes dysregulated JNK activity in quiescent phase that may contribute to checkpoint override, promoting UC carcinogenesis.	28383667
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) causes chronic inflammation and alteration of articular tissue and joints.	28384116
Inflammation	Altered Intercellular Communication	It has been shown that YKL-40 is implicated in tissue remodeling, angiogenesis and inflammation.	28384116
Pancreatitis, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	Myocarditis developed and extensive pancreatic inflammation was observed in all mice infected with CB2/04/279 or CVB/O, but not in animals infected with CB2/04/243.	28384999
hearing impairment, Inflammation, Otitis Media with Effusion	Altered Intercellular Communication	OME is characterized as an inflammation with accumulation of secretion in the tympanic cavity, leading to conductive hearing loss.	28385090
atherosclerotic	Altered Intercellular Communication	Detection of Atherosclerotic Inflammation by 68Ga-DOTATATE PET Compared to [18F]FDG PET Imaging.	28385306
atherosclerotic	Altered Intercellular Communication	This study tested the efficacy of gallium-68-labeled DOTATATE (68Ga-DOTATATE), a somatostatin receptor subtype-2 (SST2)-binding PET tracer, for imaging atherosclerotic inflammation.	28385306
atherosclerotic	Altered Intercellular Communication	We validated 68Ga-DOTATATE PET as a novel marker of atherosclerotic inflammation and confirmed that 68Ga-DOTATATE offers superior coronary imaging, excellent macrophage specificity, and better power to discriminate high-risk versus low-risk coronary lesions than [18F]FDG.	28385306
Cessation of life, Communicable Diseases, Hemorrhage, Inflammation	Altered Intercellular Communication	Reasons for removal were that PICC was not considered to be useful any longer (16), suspicion of infection (inflammation without documentation) (5) or infection (2), patient's wish (4), death (4), accidental withdrawal (2), puncture site bleeding (1), and catheter change due to extracorporeal photopheresis (1).	28386787
Inflammation, Obesity	Altered Intercellular Communication	Chemerin is believed to be a mediator for the adipose tissue inflammation that occurs in obesity.	28387898
Inflammation, Tachycardia by ECG Finding	Altered Intercellular Communication	Attenuation effects of cTnT, tachycardia and CRP suggest that cardiac stress or inflammation may be involved in mechanisms causing frequent PVC i AECOPD.	28388306
Necrotizing granulomatous inflammation, Neoplasm Metastasis	Altered Intercellular Communication	Biopsies of the left lacrimal gland revealed a silver material with associated chronic granulomatous inflammation and secondary calcification.	28388345
Inflammation, Malnutrition, Muscle (organ)	Altered Intercellular Communication	The loss of muscle in older (aged >60 years) patients in the ICU may be particularly rapid due to a perfect storm of increased catabolic factors, including systemic inflammation, disuse, protein malnutrition, and reduced anabolic stimuli.	28388378
Inflammation, Dental Plaque	Altered Intercellular Communication	Plaque neovascularization accompanies local inflammation and critically contributes to plaque instability.	28388659
Inflammation, Uveomeningoencephalitic Syndrome, Tuberculosis, Uveitis	Altered Intercellular Communication	However, the manifestations of the inflammation were complicated as they included features that could be attributed mainly to Vogt-Koyanagi-Harada (VKH) disease and tuberculous serpiginous-like uveitis.	28389634
Inflammation	Altered Intercellular Communication	Therefore, a systemic evaluation, together with specific laboratory and paraclinical investigations, were carried out to define the etiology of the inflammation and develop an optimal therapeutic plan.	28389634
Inflammation, Hyperbilirubinemia	Altered Intercellular Communication	Characteristics of the heme catabolic pathway in mild unconjugated hyperbilirubinemia and their associations with inflammation and disease prevention.	28389660
Inflammation	Altered Intercellular Communication	Furthermore, acute inflammation was more evident in erosive-ulcerative lesions (p=0.001).	28390133
vascular inflammations	Altered Intercellular Communication	Circulating leukocyte-derived microparticles act as proinflammatory mediators that reflect vascular inflammation.	28390251
Inflammation, Primary malignant neoplasm, Coronary Artery Disease	Altered Intercellular Communication	Galectin-3 binding protein (Gal-3BP) has been associated with inflammation and cancer, however, its role in coronary artery disease (CAD) and cardiovascular outcome remains unclear.	28390290
Pain Distress Question, Inflammation	Altered Intercellular Communication	An escalation in pain was observed in week 3 of treatment possibly as a result of radiation induced inflammation alongside cytotoxic chemotherapy.	28390539
Inflammation, Lewy Bodies, Parkinson Disease, "Alzheimers Disease", palladium, Presenile dementia, dendritic lamellar body, Data types - Address	Altered Intercellular Communication	Enhanced inflammation has been associated with Alzheimer's disease (AD) and diseases with Lewy body (LB) pathology, such as Parkinson's disease (PD) and dementia with Lewy bodies (DLB).	28390825
Inflammation, Angular, Data types - Address	Altered Intercellular Communication	One issue is whether amyloid and tangle pathology, features of AD, or a-synuclein LB pathology have similar or different effects on brain inflammation.	28390825
Inflammation, Intestinal Diseases	Altered Intercellular Communication	Elevated fecal calprotectin (FC) is a non-invasive marker of inflammation indicating bowel disease.	28391117
Arterial Stiffness, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation and Arterial Stiffness in Chronic Kidney Disease: Findings From the CRIC Study.	28391349
Arterial Stiffness, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation is proposed to have a role in the development of arterial stiffness, and CKD is recognized as a proinflammatory state.	28391349
Arterial Stiffness, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	However, no large scale investigations have examined the impact of inflammation on the progression of arterial stiffness in CKD.	28391349
Arterial Stiffness, Inflammation	Altered Intercellular Communication	In longitudinal analyses, there were few meaningful correlations between baseline levels of inflammation and changes in metrics of arterial stiffness over time.	28391349
Arterial Stiffness, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	In a large cohort of CKD participants, we observed multiple significant correlations between initial markers of inflammation and metrics of arterial stiffness, but baseline inflammation did not predict changes in arterial stiffness over time.	28391349
Inflammation	Altered Intercellular Communication	Inflammation and Cyclooxygenase-2 (COX-2) as a part of it are common in BPH specimens and may play a role in the pathogenesis of the disease through cytokines that promote cell growth or lead to smooth muscle contraction.	28391389
vascular inflammations	Altered Intercellular Communication	Laboratory findings have suggested that systemic and vascular inflammation can impair the antiatherogenic function of high-density lipoproteins (HDLs).	28391888
Inflammation, HIV	Altered Intercellular Communication	Persistent immune activation and inflammation in virologically suppressed human immunodeficiency virus (HIV) infection are linked to excess cardiovascular risk.	28391912
Inflammation, HIV Infections	Altered Intercellular Communication	In virologically suppressed individuals with HIV infection, atorvastatin did not significantly decrease levels of soluble or cellular biomarkers of immune activation and inflammation but resulted in robust reductions in LDL cholesterol, oxLDL, and lipoprotein-associated phospholipase A2, biomarkers associated with cardiovascular risk.	28391912
Inflammation, Neoplasm Metastasis	Altered Intercellular Communication	Although many etiologic models have been explored, secondary damage caused by continued inflammation and iron exposure from red blood cell lysis may explain poor outcomes at distant follow-up.	28392117
Inflammation, Angina Pectoris	Altered Intercellular Communication	We investigated the relationship between endocan (a marker of systemic inflammation) and the development of coronary collateral circulation (CCC) as evaluated by coronary angiography in patients with chronic stable angina pectoris.	28393589
Inflammation, Dental Plaque	Altered Intercellular Communication	Efficacy of triphala extract and chlorhexidine mouth rinse against plaque accumulation and gingival inflammation among female undergraduates: A randomized controlled trial.	28393817
Inflammation, Dental Plaque	Altered Intercellular Communication	To know the efficacy of Triphala extract and Chlorhexidine mouth rinse against plaque and gingival inflammation.	28393817
Inflammation, Peripheral Arterial Diseases	Altered Intercellular Communication	Inflammation plays an important role in the initiation and progression of peripheral artery disease (PAD).	28394111
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Data regarding the prognostic implication of diabetes and inflammation on all-cause mortality in patients with symptomatic PAD and preserved left ventricular ejection fraction (LVEF >50%).	28394111
Inflammation, Arthritis, Gouty	Altered Intercellular Communication	Genetic variants of PPAR-gamma coactivator 1B augment NLRP3-mediated inflammation in gouty arthritis.	28394398
Arthritis, Hyperuricemia, Gout	Altered Intercellular Communication	Gout is characterized by recurrent attacks of arthritis with hyperuricaemia and urate crystal-induced inflammation.	28394398
Inflammation	Altered Intercellular Communication	Although urate transporters are known as risk factors, the immunogenetics of gouty inflammation remains unclear.	28394398
Inflammation, Arthritis, Gouty	Altered Intercellular Communication	These data suggest that variants of PPARGC1B , a regulator of metabolism and inflammation, contribute to the pathogenesis of gouty arthritis.	28394398
Inflammation, Fibrosis Assessment, Mast cell infiltration	Altered Intercellular Communication	Non-Hunner-type IC is characterized by severe fibrosis and increased mast cell infiltration, whereas Hunner-type IC is characterized by severe inflammation and urothelial denudation in the entire bladder.	28394416
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	The gut microbiota affects host lipid and glucose metabolism, satiety, and chronic low-grade inflammation to contribute to obesity and type 2 diabetes.	28396144
Respiratory Tract Infections, Bronchitis, Pneumonia	Altered Intercellular Communication	In these cases, it was mainly used for postoperative anti-inflammation and treating upper respiratory infection, pneumonia and bronchitis.	28397057
Chronic otitis	Altered Intercellular Communication	Subjects with chronic otitis media without active inflammation (dry ear) had similar middle ear microbiomes as the normal middle ears group.	28397271
Proteobacteria, Chronic otitis	Altered Intercellular Communication	Subjects with chronic otitis media with active inflammation (wet ear) had a lower prevalence of Proteobacteria and a higher prevalence of Firmicutes than the normal middle ears.	28397271
Acute inflammation, Chronic otitis	Altered Intercellular Communication	Alteration of the middle ear microbiome may contribute to the pathogenesis of chronic otitis media with active inflammation.	28397271
Dysphonia, Laryngitis	Altered Intercellular Communication	This is a retrospective chart review of adult patients with persistent dysphonia plus evidence of laryngeal inflammation who underwent biopsy for culture at a tertiary care medical center.	28397557
Laryngitis	Altered Intercellular Communication	For MSSA- and MRSA-associated laryngitis, an extended course of antibiotics may be necessary for symptom improvement and resolution of laryngeal inflammation.	28397557
Inflammation, Carcinogenesis	Altered Intercellular Communication	Chronic inflammation is postulated to be one crucial mechanism for prostate carcinogenesis.	28398294
Inflammation, Asthma	Altered Intercellular Communication	Serum periostin relates to type-2 inflammation and lung function in asthma: Data from the large population-based cohort Swedish GA(2)LEN.	28398635
Inflammation, Asthma	Altered Intercellular Communication	Periostin has been suggested as a novel, phenotype-specific biomarker for asthma driven by type 2 inflammation.	28398635
Colonization	Altered Intercellular Communication	Notable features of CRSwNP are the frequent presence of type 2 allergic inflammation and high prevalence of Staphylococcus aureus (SA) colonization.	28398769
Epithelial Damage, Inflammation, polyps	Altered Intercellular Communication	As inflammation persists, sinus tissue undergoes epithelial damage and repair along with polyp growth, despite active medical management.	28398769
Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is a long-time inflammatory condition arising from aberrant immune activation in the colon and the rectum.	28398870
Degenerative polyarthritis, Inflammation, Obesity	Altered Intercellular Communication	Risk factors for OA include age and obesity with inflammation identified as a key mediator of disease pathogenesis.	28399156
Inflammation, Hemorrhage, Obstruction, Meckel Diverticulum	Altered Intercellular Communication	Hemorrhage, obstruction and inflammation are most common complications of Meckel's diverticulum.	28399839
Inflammation, Gastric Tissue, Perforation (observation)	Altered Intercellular Communication	Perforation was due to progressive inflammation and presence of gastric and pancreatic tissue found on histopathology.	28399839
Pyelonephritis, Nephritis	Altered Intercellular Communication	Xanthogranulomatous pyelonephritis is a rare and serious manifestation of chronic kidney inflammation that can be life-threatening if not recognized and treated appropriately, often with antibiotics and surgery.	28399929
Pyelonephritis, Xanthogranulomatous, Inflammation	Altered Intercellular Communication	Based on classic radiographic and histopathologic findings, she was ultimately diagnosed with xanthogranulomatous pyelonephritis of her left kidney, which was a direct consequence of chronic inflammation.	28399929
Pleural Effusion, CTCAE, Inflammation	Altered Intercellular Communication	This inflammation exhibited spread to local tissues and across her left hemidiaphragm, resulting in a unilateral pleural effusion which explained her chest discomfort.	28399929
Perforation of rectum, Colorectal Carcinoma	Altered Intercellular Communication	A total of 43 patients with surgically and pathologically confirmed colorectal perforation caused by either colorectal cancer (n =27) or an inflammatory conditions (n = 16) were identified.	28401282
Esophagitis, Esophageal carcinoma	Altered Intercellular Communication	Clinical significance of the correlation between PLCE 1 and PRKCA in esophageal inflammation and esophageal carcinoma.	28402280
Inflammation, Primary malignant neoplasm, Carcinoma of lung	Altered Intercellular Communication	To reflect the broader role of inflammation in lung cancer, we examined a large panel of 33 inflammatory proteins in the sera of 129 lung cancer patients selected from the National Cancer Institute-Maryland case-control study.	28402963
Single organ dysfunction, Pancreatitis, Pancreatitis, Acute	Altered Intercellular Communication	Evaluation of extrapancreatic inflammation on abdominal computed tomography as an early predictor of organ failure in acute pancreatitis as defined by the revised Atlanta classification.	28403081
Communicable Diseases, Inflammation, Respiratory Tract Infections	Altered Intercellular Communication	Increased respiratory iron content has been associated with respiratory tract infection, though it is unclear if this represents a predisposing factor for infection or the sequelae of inflammation.	28403845
Inflammation, Carcinogenesis, Neoplasms	Altered Intercellular Communication	CCL4 (C-C chemokine ligand 4), a macrophage inflammatory protein with a key role in inflammation and immune-regulation, was implicated in carcinogenesis by facilitating instability in the tumor environment.	28404909
Inflammation, Helicobacter pylori	Altered Intercellular Communication	Toll-like receptor (TLR) genes, which play critical roles in Helicobacter pylori induced chronic inflammation, may also be implicated in GC susceptibility.	28404962
ARCN1 gene, Inflammation	Altered Intercellular Communication	MicroRNA-125a and -b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPD.	28405612
Inflammation, Infection	Altered Intercellular Communication	Influenza A virus (IAV) infections lead to severe inflammation in the airways.	28405612
ARCN1 gene, Chronic Obstructive Airway Disease, Infection, Airway structure	Altered Intercellular Communication	Patients with chronic obstructive pulmonary disease (COPD) characteristically have exaggerated airway inflammation and are more susceptible to infections with severe symptoms and increased mortality.	28405612
ARCN1 gene, Communicable Diseases, Inflammation	Altered Intercellular Communication	The mechanisms that control inflammation during IAV infection and the mechanisms of immune dysregulation in COPD are unclear.	28405612
Communicable Diseases, Inflammation	Altered Intercellular Communication	IAV infection increased the expression of miR-125a or -b, which directly reduced the expression of A20 and mitochondrial antiviral signaling (MAVS), and caused exaggerated inflammation and impaired antiviral responses.	28405612
Refractory anemias, Inflammation	Altered Intercellular Communication	Use of bisphosphonate significantly increased the BMD of the spine in patients over a period of 3 years and was important for maintaining the BMD among patients with RA under the control of inflammation and disease activity.	28405825
Inflammation, Toxic effect of venom, Scorpion sting, Scorpion Venoms	Altered Intercellular Communication	The pathophysiology of envenomation is related to an excessive inflammatory response; however, no studies have identified the differences in immune responses to scorpion stings and mainly the mechanisms of inflammation between children and adults, which may be a determinant key of the susceptibility of children to scorpion envenomation.	28405853
Attention deficit hyperactivity disorder	Altered Intercellular Communication	Systemic Inflammation during the First Postnatal Month and the Risk of Attention Deficit Hyperactivity Disorder Characteristics among 10 year-old Children Born Extremely Preterm.	28405874
Inflammation, Attention deficit hyperactivity disorder	Altered Intercellular Communication	Systemic inflammation during the first postnatal month among children born extremely preterm appears to increase the risk of teacher-identified ADHD characteristics, and high concentrations of proteins with neurotrophic properties appear capable of modulating this increased risk.	28405874
Inflammation, Atherosclerosis	Altered Intercellular Communication	Our results suggest that the AT of PAD patients infiltrated with macrophages produces more cytokines involved in the development of inflammation and atherosclerosis.	28406704
Inflammation, Community acquired pneumonia	Altered Intercellular Communication	To explore the performance of the neutrophil-to-lymphocyte ratio (NLR), an index of systemic inflammation that predicts prognosis of several diseases, in a cohort of elderly adults with community-acquired pneumonia (CAP).	28407209
Biliary hyperplasia, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Multiple genes related to liver fibrosis, inflammation, and biliary hyperplasia were increased in H19-BDL versus null-BDL mice, whereas genes in BA synthesis were decreased.	28407375
Inflammation, muscle mass	Altered Intercellular Communication	Is the Body Cell Mass Index (BCMI) a useful prognostic factor to describe nutritional, inflammation and muscle mass status in hospitalized elderly?	28408051
Inflammation	Altered Intercellular Communication	The good concordance between PAS-II and SDAI supports their use in clinical practice, especially if biomarkers of inflammation or the possibility of joint count are not available.	28408110
Inflammation, Atherosclerosis	Altered Intercellular Communication	Here we investigated the effects of iNAMPT overexpression in leukocytes on inflammation and atherosclerosis.	28408371
Inflammation, Immune System Diseases	Altered Intercellular Communication	Bacteria secrete nanometer-sized extracellular vesicles (EVs), which may induce more immune dysfunction and inflammation than the bacteria themselves.	28408748
Inflammation, Neurologic Deficits, Loss of neurons	Altered Intercellular Communication	Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss.	28409281
Inflammation, Behavior, Prodromal Symptoms	Altered Intercellular Communication	Thus, poly-GA triggers behavioral deficits through inflammation and protein sequestration that likely contribute to the prodromal symptoms and disease progression of C9orf72 patients.	28409281
Granulomatous inflammation, Lesion of spleen	Altered Intercellular Communication	Endoscopic ultrasound-guided fine needle aspiration of splenic lesion revealed granulomatous inflammation.	28410696
Inflammation, Osteoporotic Fractures	Altered Intercellular Communication	Chronic inflammation provides the substrate for various mechanisms involved in osteoporotic fracture.	28411093
Inflammation, Crohn Disease	Altered Intercellular Communication	Vitamin D modulates inflammation in Crohn's disease (CD).	28412753
Inflammation, Adipose tissue loss	Altered Intercellular Communication	This is particularly evident in big chronic wounds with considerable tissue loss, which become senescent in the process of inflammation or proliferation losing the ability to epithelialize.	28413063
Coma (genus), Inflammation, Malaria, Cerebral, Vascular occlusion, Cessation of life	Altered Intercellular Communication	Cytoadherence, sequestration, alterations in cytokine expression, inflammation, and microvascular obstruction are all hypothesized to be important in the aetio-pathogenesis of coma which characterizes cerebral malaria and the death which sometimes result.	28413714
Inflammation, Abscess	Altered Intercellular Communication	The Apparent Diffusion Coefficient (ADC) as a Potential Marker of Inflammation Associated with Body Abscesses.	28413873
Inflammation, Resectable Hepatocellular Carcinoma	Altered Intercellular Communication	The predictive value of integrated inflammation scores in the survival of patients with resected hepatocellular carcinoma: A Retrospective Cohort Study.	28414120
Inflammation, Liver carcinoma, Communicable Diseases, Hepatitis B, FAM126A gene	Altered Intercellular Communication	Evidence supports the predictive potential of inflammatory marker-derived scores (inflammation scores) and hepatitis B virus (HBV) infection on prognosis of patients with hepatocellular carcinoma (HCC).	28414120
Inflammation, FAM126A gene	Altered Intercellular Communication	Preoperative and dynamic changes in integrated inflammation scores, particularly for coCRP/ALB-PLR were important and stable prognostic markers in HCC.	28414120
Psoriasis, Inflammatory dermatosis, Dermatitis	Altered Intercellular Communication	Psoriasis is a common inflammatory skin disease and dendritic cells (DCs) play crucial role in the development of skin inflammation.	28414181
Obesity	Altered Intercellular Communication	A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity.	28414311
Inflammation, Obesity	Altered Intercellular Communication	In obesity, inflammation of white adipose tissue (AT) is associated with diminished generation of beige adipocytes ('beige adipogenesis'), a thermogenic and energy-dissipating function mediated by beige adipocytes that express the uncoupling protein UCP1.	28414311
Obesity	Altered Intercellular Communication	Our findings, established in both mouse systems and human systems, reveal a self-sustained cycle of inflammation-driven impairment of beige adipogenesis in obesity.	28414311
Fibrosis Assessment	Altered Intercellular Communication	Both bleomycin-induced inflammation and fibrosis were reduced in P2Y2R-deficient compared to wild type animals.	28415591
Inflammation, Fibrosis Assessment, Autoimmune Chronic Hepatitis	Altered Intercellular Communication	31Phosphorus magnetic resonance spectroscopy of the liver for evaluating inflammation and fibrosis in autoimmune hepatitis.	28415898
Inflammation, Fibrosis Assessment, Autoimmune Chronic Hepatitis	Altered Intercellular Communication	Liver biopsy is the gold standard in evaluating inflammation and fibrosis in autoimmune hepatitis.	28415898
Inflammation	Altered Intercellular Communication	Phosphoenolpuryvate (PEP) correlated with the grade of inflammation (r = 0.746, p = .005) and thromboplastin time (r = 0.592, p = .043).	28415898
Inflammation	Altered Intercellular Communication	It also differentiated patients with active inflammation from patients without (t = 3.781, p = .009).	28415898
Inflammation, Fibrosis Assessment, Insemination, Artificial, Homologous	Altered Intercellular Communication	31P MRS seems to detect active inflammation and advanced fibrosis in AIH patients.	28415898
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	AAAs are associated with features of systemic inflammation and endothelial dysfunction.	28416190
Heart Diseases, atherosclerotic	Altered Intercellular Communication	There are confirmed beneficiary effects of exercise on atherosclerotic inflammation of ischemia-associated heart diseases.	28417620
Myocardial Ischemia, atherosclerotic	Altered Intercellular Communication	It seems that exercise may yield a better control of atherosclerotic inflammation in patients with ischemic heart disease through the induction of regulatory T cells.	28417620
Inflammation	Altered Intercellular Communication	The role of chronic inflammation in DKD is becoming widely accepted.	28418911
Osteitis, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8, Osteoporosis	Altered Intercellular Communication	Taken together, T1D combined with estrogen deficiency has a major effect on bone inflammation, which contributes to suppressed bone formation and osteoporosis.	28419209
Inflammation, Tuberculosis, Meningeal, HIV Infections	Altered Intercellular Communication	Leukotriene A4 Hydrolase Genotype and HIV Infection Influence Intracerebral Inflammation and Survival From Tuberculous Meningitis.	28419368
Inflammation, Fibrosis Assessment, Fatty degeneration, Liver Stiffness	Altered Intercellular Communication	Secondary outcomes included changes in steatosis, lobular inflammation, hepatocyte ballooning, NAS and fibrosis score, and anthropometric measurements, as well as glycemic, lipid, and liver profiles and liver stiffness measurements.	28419855
Inflammation, Infection, Cerebrovascular accident	Altered Intercellular Communication	Stroke-associated immunosuppression and inflammation are increasingly recognized as factors that trigger infections and thus, potentially influence the outcome after stroke.	28419988
Inflammation, Pain Distress Question	Altered Intercellular Communication	The present data show that subclinical inflammation is related to increased pain sensitivity, suggesting a potential role of inflammation in experimental pain which may be of importance for the development of clinical pain.	28420008
Pancreatic Trypsin Secretory Inhibitor, Kazal, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Transcriptome data revealed changes in genes linked with inflammation (CD68 and SAA), regeneration (SPINK1 and HGF), fibrosis (COL1A1), and stem cells (CD45).	28420441
Arterial Stiffness, Inflammation, Microvascular Angina, Atherosclerosis	Altered Intercellular Communication	The role of potential mechanistic pathways of arterial stiffness, atherosclerosis, microvascular disease, and inflammation were explored.	28420646
Inflammation, Sinus Thrombosis, Intracranial, Cerebral Infarction	Altered Intercellular Communication	However, she delivered a stillbirth, after which there was recurrence of acute cerebral infarction with LMCA occlusion, sinus thrombosis, and cranial base inflammation.	28420846
Meningitis	Altered Intercellular Communication	A thrice-weekly 100 mg dose of intrathecal isoniazid (INH) improved the signs of meningeal inflammation.	28420846
Inflammation, Psoriasis	Altered Intercellular Communication	CD93 is involved in angiogenesis and inflammation, both of which are key processes in the pathogenesis of psoriasis.	28421233
Inflammation, Obesity	Altered Intercellular Communication	Low-grade chronic inflammation in morbid obesity is associated with impaired iron metabolism.	28421792
Ischemia, Inflammation, Atrial Fibrillation by ECG Finding, Myopericarditis, osteoclast activating factor, Traumatic injury, physiopathological, Autonomic instability	Altered Intercellular Communication	From a pathophysiological point of view, a myriad of factors such as trauma, atrial dilation, ischemia, mechanical myopericarditis, autonomic imbalance, loss of connexins, AF nest remodeling, inflammation, sutures, and dysfunction caused by postextracorporeal circulation can contribute to postoperative atrial fibrillation (POAF) resulting in a longer hospital stay and consequently higher cost.	28422282
Inflammation, Anemia, Aspects of mortality statistics	Altered Intercellular Communication	Mortality is associated with inflammation, anemia, specific diseases and treatments, and molecular markers.	28422991
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Low vitamin D status is associated with inflammation in patients with prostate cancer.	28423553
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Inflammation may be an important mediator for prostate cancer progression in patients with low vitamin D status.	28423553
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Altered expression of HMGB1 has been implicated in a wide range of pathological processes, including inflammation and cancer.	28423715
Diverticulum, Inflammation, Colon diverticulum anatomic structure, Sigmoid colon	Altered Intercellular Communication	Few studies have shown the associations between colonic diverticula and endoscopic findings such as location, inflammation, number of diverticula, sigmoid colon rigidity, and bowel habits.	28425144
Diverticulum, Inflammation, Sigmoid colon	Altered Intercellular Communication	Location and number of diverticula, inflammation, and sigmoid colon rigidity were evaluated from endoscopy results.	28425144
Inflammation, Multiple colonic diverticula, Colon diverticulum anatomic structure, Sigmoid colon, Constipation	Altered Intercellular Communication	In multivariate analysis, presence of constipation was associated with a significantly lower likelihood of left-sided colonic diverticula (odds ratio = 0.40, 95% confidence interval 0.20-0.82, P = 0.012), whereas right-sided and bilateral-sided colonic diverticula, multiple colonic diverticula, inflammation findings, and sigmoid colon rigidity were not related to bowel habits.	28425144
Inflammation, Colon diverticulum anatomic structure, Multiple diverticula, Sigmoid colon, Constipation	Altered Intercellular Communication	Among endoscopic findings related to colonic diverticula and bowel habits, only left-sided colonic diverticula were inversely associated with constipation, whereas inflammation findings, multiple diverticula, and sigmoid colon rigidity were not related to bowel habits.	28425144
Inflammation, Colon diverticulum anatomic structure	Altered Intercellular Communication	However, the association of inflammation findings with colonic diverticula and bowel habits should be further studied.	28425144
ARCN1 gene, Abnormal inflammatory response	Altered Intercellular Communication	SUV39H1 Reduction Is Implicated in Abnormal Inflammation in COPD.	28425504
Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic obstructive pulmonary disease(COPD) is characterized by enhanced chronic inflammation in the airways, lung parenchyma, and circulation.	28425504
ARCN1 gene, Abnormal inflammatory response	Altered Intercellular Communication	We investigated whether SUV39H1, a histone methyltransferase, is causatively implicated in the abnormal inflammation observed in COPD.	28425504
ARCN1 gene, Inflammation	Altered Intercellular Communication	SUV39H1 knockdown reproduced the pattern of COPD inflammation, whereas SUV39H1 overexpression in COPD HSAEpCs rescued the H3K9me3 levels and suppressed inflammation.	28425504
ARCN1 gene, Inflammation	Altered Intercellular Communication	In COPD mice, chaetocin further repressed the SUV39H1/H3K9me3 levels and enhanced inflammation.	28425504
Exanthema, Inflammatory abnormality of the eye, Serositis, Myalgia, CTCAE 5	Altered Intercellular Communication	Systemic symptoms can include rash, myalgia, ocular inflammation, and serositis.	28427379
Hereditary Autoinflammatory Diseases	Altered Intercellular Communication	Given her protracted clinical course and maternal history of a poorly defined inflammatory condition, an autoinflammatory disease was considered.	28427379
Inflammation	Altered Intercellular Communication	Increasing evidence has indicated that insulin resistance is associated with inflammation.	28428029
Infiltration, Necrosis with inflammation	Altered Intercellular Communication	The prominent features were lobular necrosis/inflammation (97.7%), plasma cell infiltration (96.4%), emperipolesis (89.3%), pigmented macrophages (84.5%), cobblestone appearance of hepatocytes (82.6%) and perivenular necroinflammatory activity, including centrilobular necrosis (81.4%).	28428284
Inflammation, Malnutrition, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	Both inflammation and malnutrition have been reported to be closely linked to atherosclerosis, especially in patients with chronic kidney disease (CKD).	28428450
SNCG gene, Inflammation, Lewy Bodies	Altered Intercellular Communication	This microbiological pattern of gut microflora can trigger local inflammation followed by aggregation of a-synuclein and generation of Lewy bodies.	28429209
Inflammation, atherosclerotic	Altered Intercellular Communication	Associations of Osteocalcin, Osteoprotegerin, and Calcitonin with Inflammation Biomarkers in Atherosclerotic Plaques of Coronary Arteries.	28429221
Inflammation, Obesity	Altered Intercellular Communication	Obesity is associated with a state of chronic low-grade inflammation.	28429893
Inflammation	Altered Intercellular Communication	This may occur because of depressing inflammation and improving circulating EPCs.	28430117
Inflammation, Cachexia, Cardiovascular system	Altered Intercellular Communication	The Association of Ankle Brachial Index, Protein-Energy Wasting, and Inflammation Status with Cardiovascular Mortality in Patients on Chronic Hemodialysis.	28430145
HD Term Type, Inflammation	Altered Intercellular Communication	We investigated the association of abnormal ankle brachial index (ABI), PEW, and chronic inflammation status with clinical prognosis in HD patients.	28430145
prostatitis	Altered Intercellular Communication	Prostate-specific antigen increase during dutasteride to indicate the need for prostate biopsy: influence of prostatic inflammation.	28430341
prostatitis	Altered Intercellular Communication	We focused our attention on the rate of the first PSA increase and on the influence of prostatic inflammation.	28430341
Inflammation, Liver carcinoma	Altered Intercellular Communication	Systemic inflammation response index (SIRI) predicts prognosis in hepatocellular carcinoma patients.	28430597
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The systemic inflammation response index (SIRI) is a useful tool for predicting prognosis in some types of cancer.	28430597
Communicable Diseases, Inflammation	Altered Intercellular Communication	However, distinguishing between inflammation and infection is a challenge.	28430741
Inflammation, Disease remission	Altered Intercellular Communication	At d2, half of the patients (6/12) showed active disease, whereas ileo-colonoscopy revealed significant inflammation in 5/15 (33%).	28431493
Inflammation, ovarian neoplasm	Altered Intercellular Communication	Inflammation plays an important role in the pathogenesis of ovarian cancer.	28431566
ovarian neoplasm	Altered Intercellular Communication	The CRP/Alb is a novel independent marker of poor prognosis among ovarian cancer patients and shows superior prognostic ability compared to the established inflammation-based prognostic indices.	28431566
Inflammation, Psoriasis	Altered Intercellular Communication	Serum peptides as putative modulators of inflammation in psoriasis.	28431948
Inflammation	Altered Intercellular Communication	Interleukin-6 (IL-6) is a driver of inflammation and associated endothelial cell activation in acute coronary syndromes.	28432157
Inflammation, Hyperparathyroidism, Primary	Altered Intercellular Communication	Low-grade inflammation and tryptophan-kynurenine pathway activation are associated with adverse cardiac remodeling in primary hyperparathyroidism: the EPATH trial.	28432842
Inflammation, Hyperparathyroidism, Primary, Electrocardiogram: left ventricle hypertrophy (finding)	Altered Intercellular Communication	Primary hyperparathyroidism (pHPT) is associated with low-grade inflammation, left ventricular hypertrophy and increased cardiovascular mortality, but the association between inflammatory markers and parameters of adverse cardiac remodeling is unknown.	28432842
Inflammation	Altered Intercellular Communication	Conclusions: Cardiac remodeling is common in pHPT and is associated with low-grade inflammation and activation of the tryptophan-kynurenine pathway.	28432842
Degenerative polyarthritis, Inflammation, Pain Distress Question	Altered Intercellular Communication	The role of inflammation and pain in osteoarthritis (OA) is not fully understood.	28433814
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	It has been characterized as either inflammation of the median nerve caused by compression or noninflammatory fibrosis of the subsynovial connective tissue (SSCT).	28433831
Inflammation, Hyperreactivity, Data types - Address	Altered Intercellular Communication	We show hyperreactivity of Ab plaque-associated microglia upon systemic inflammation in transgenic AD mouse models (i.e., 5XFAD and APP23).	28434692
Inflammation, Traumatic injury	Altered Intercellular Communication	High mastery may protect against elevated systemic inflammation associated with substantial lifetime trauma exposure.	28437379
Inflammation	Altered Intercellular Communication	Individuals who experience declines in mastery may be most susceptible to increases in inflammation associated with chronic stress.	28437379
Airway structure, ARCN1 gene	Altered Intercellular Communication	Post-bronchodilator Reversibility of FEV1 and Eosinophilic Airway Inflammation in COPD.	28438346
Airway structure, ARCN1 gene	Altered Intercellular Communication	The relationship between bronchodilator responsiveness and eosinophilic airway inflammation has not been well documented in COPD.	28438346
Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	To investigate whether systemic inflammation in acutely admitted older medical patients (age >65 years) is associated with physical performance and organ dysfunction.	28438470
Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	Organ dysfunction's association with physical performance, and whether these associations are mediated by systemic inflammation, was also investigated.	28438470
Inflammation	Altered Intercellular Communication	FI-OutRef was also associated with physical performance (all p<0.001); suPAR being the inflammatory biomarker with the highest impact when adjusting for inflammation.	28438470
Intraocular inflammation	Altered Intercellular Communication	This case highlights IgG4-RD as a rare cause of intraocular inflammation that may progress to involve the orbit.	28438752
IgG4-Related Sclerosing Disease	Altered Intercellular Communication	IgG4-related disease (IgG4-RD) is a rare, chronic inflammatory condition that may involve nearly every organ system.	28438752
Increased insulin level, Inflammation, Obesity	Altered Intercellular Communication	We conclude that a decrease in mitochondrial BCAA degradation and an increase in inflammation in SAT co-occur and associate with hyperinsulinemia and large adipocyte size in unhealthy obesity.	28439093
Inflammation	Altered Intercellular Communication	Factors contributing to elevated inflammation in racial/ethnic minority populations are not well understood.	28439184
Inflammation, Metabolic Diseases	Altered Intercellular Communication	Abdominal fat accumulation after menopause is associated with low-grade inflammation and increased risk of metabolic disorders.	28440046
Airway structure, Asthma	Altered Intercellular Communication	Instead, sST2 predicts a subphenotype of asthma characterized by increased levels of FeNO, a marker for eosinophilic airway inflammation.	28440062
Airway structure, Asthma, Wheezing	Altered Intercellular Communication	Our study indicates that sST2 in preschool wheezers has predictive value for the development of eosinophilic airway inflammation in asthmatic children at school age.	28440062
Inflammation, Cardiac function	Altered Intercellular Communication	A total of 3 weeks following injection, this resulted in severe inflammation and significant deterioration of cardiac function.	28440472
Inflammation	Altered Intercellular Communication	After population-based baseline screening, 145 precursor and 335 chronic inflammation cases were endoscopically surveyed for six years.	28440945
RANGAP1 wt Allele, Inflammation, Dysplasia	Altered Intercellular Communication	Surveillance of interval and baseline diagnoses for 18 severe dysplasia (SD) cases later detected were: 13, 23, 39, and 44 months since a diagnosis of chronic inflammation in four cases; 6, 6, 6, 11, 13, 16, 16, and 23 months since mild dysplasia (mD) diagnoses in eight; and 6, 9, 10, 13, 18, and 48 months since moderate dysplasia (MD) diagnoses in six.	28440945
Exophthalmos, Conjunctivitis, Corneal Ulcer	Altered Intercellular Communication	We examined a conjunctival biopsy from a 69-year-old woman who developed unilateral conjunctival inflammation together with a neurotrophic corneal ulcer and proptosis.	28441073
Dryness (characteristic), Inflammatory abnormality of the eye, Nerve injury	Altered Intercellular Communication	The functional role of Langerhans cells (LCs) in ocular surface inflammation and nerve damage in dry eye (DE) disease has yet to be determined.	28441413
Inflammatory abnormality of the eye, Disease	Altered Intercellular Communication	These data support a functional role for LCs in negatively regulating ocular surface inflammation and exhibiting a neuroprotective function in DE disease.	28441413
Inflammation	Altered Intercellular Communication	The extent to which the gastrointestinal microbiome and peripheral inflammation are associated with ME/CFS remains unclear.	28441964
Inflammation, Anemia	Altered Intercellular Communication	Appropriate investigations for iron status and inflammation/infection screening, need to be integral in the evaluation of anaemia and its causes before anaemia control interventions are implemented.	28441968
Granuloma	Altered Intercellular Communication	Histopathology shows interstitial granulomas composed of epitheloid histiocytes in the reticular dermis with surrounding foci of collagen degeneration and variable neutrophilic inflammation.	28442268
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	Interleukin-6 (IL-6) and its receptor (IL-6R) were regarded to be responsible for the occurrence of gastric cancer for their regulation roles in the inflammation.	28442395
Inflammation, Platelet destruction	Altered Intercellular Communication	A shared immunologic pathway leading to mucosal inflammation and platelet destruction has been proposed.	28442528
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The correlation between 25(OH)D levels, inflammation markers, BMI, and FLI showed an increased risk of cardiovascular disease in this cohort of workers.	28443804
Janus kinase, Inflammation	Altered Intercellular Communication	Janus kinase (JAK) and spleen tyrosine kinase (SYK) play critical functions in T-cell activation and in inflammation.	28445193
Intraocular inflammation, Failure (biologic function), Uveitis	Altered Intercellular Communication	The primary end point was the time to treatment failure, defined according to a multicomponent intraocular inflammation score that was based on the Standardization of Uveitis Nomenclature criteria.	28445659
Pulmonary arterial hypertension, Inflammation, Polycyclic Hydrocarbons, Aromatic	Altered Intercellular Communication	Chronic inflammation emerges as a feature of the pathogenesis of pulmonary arterial hypertension (PAH) in experimental models.	28446163
Inflammation, Traumatic injury	Altered Intercellular Communication	Oxylipins are potent lipid mediators demonstrated to initiate and regulate inflammation yet little is known regarding their involvement in the response to surgical trauma.	28446191
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Recent data suggest its association with low-grade inflammation in osteoarthritis (OA).	28446208
Refractory anemias, Inflammation	Altered Intercellular Communication	Our data provide the first evidence of S100A11 up-regulation and its association with inflammation and disease activity in patients with RA.	28446208
Sepsis, Inflammation	Altered Intercellular Communication	Mesenchymal stem cells (MSCs) have been shown to reduce sepsis-induced inflammation and improve survival in mouse models of sepsis.	28446249
Sepsis	Altered Intercellular Communication	CD16+ monocytes are proinflammatory and abundant in inflammatory conditions such as sepsis.	28446249
Hypertension, CTCAE	Altered Intercellular Communication	A pro-inflammatory diet is thought to lead to hypertension through oxidative stress and vessel wall inflammation.	28446366
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Skin histopathologic examination demonstrated the presence of mucin deposits, dermal fibrosis, fibrocytes and perivascular inflammation.	28446858
Inflammation, Obesity	Altered Intercellular Communication	The association between inflammation, obesity and elevated blood pressure in 16-25-year-old females.	28447628
Inflammation, Obesity	Altered Intercellular Communication	There is evidence to show an association between inflammation, obesity and elevated blood pressure.	28447628
Inflammation	Altered Intercellular Communication	Chronic inflammation is linked to many chronic conditions.	28448077
Inflammation	Altered Intercellular Communication	One of the strongest modulators of chronic inflammation is diet.	28448077
Inflammation, Obesity	Altered Intercellular Communication	Various inflammation parameters are increased with childhood obesity, but few comparable data are found in lean growing athletes.	28448210
Sarcoidosis, Myocarditis	Altered Intercellular Communication	Conclusion Quantitative myocardial tissue characterization with T1 and T2 mapping may enable noninvasive recognition of cardiac involvement and activity of myocardial inflammation in patients with systemic sarcoidosis.	28448233
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	There is increasing evidence for the involvement of chronic inflammation and oxidative stress in the pathogenesis of Alzheimer's disease (AD).	28448946
Ulcerative Colitis	Altered Intercellular Communication	The endoscopic features of IBD-TA at initial diagnosis (n = 8) showed discontinuous and focal mucosal inflammations (n = 7, 87.5%), and only one case was diagnosed as ulcerative colitis (UC) at the first colonoscopy.	28449344
Inflammation	Altered Intercellular Communication	TCM is characterized by changes in cardiomyocyte and mitochondrial morphology accompanied by a macrophage-dominated cardiac inflammation.	28449778
Inflammation, Mitral restenosis	Altered Intercellular Communication	Late mitral restenosis after percutaneous commissurotomy: Predictive value of inflammation and extracellular matrix remodeling biomarkers.	28450150
Inflammation, Mitral restenosis	Altered Intercellular Communication	The role of chronic inflammation in mitral restenosis after percutaneous mitral commissurotomy (PMC) is still controversial.	28450150
Inflammation, Mitral restenosis	Altered Intercellular Communication	We sought to assess the predictive value of inflammation and extracellular matrix (ECM) remodeling biomarkers in late mitral restenosis after PMC.	28450150
Inflammation, Mitral restenosis	Altered Intercellular Communication	Chronic inflammation and ECM remodeling are involved in late mitral restenosis after PMC.	28450150
Alzheimers Disease", Data types - Address, Cell body of neuron	Altered Intercellular Communication	Alzheimer's disease (AD), a debilitating neurodegenerative illness, is characterized by neuronal cell loss, mental deficits, and abnormalities in several neurotransmitter and protein systems.	28450267
Inflammation, Liver Failure, Acute	Altered Intercellular Communication	MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure.	28450389
Hepatitis, Necrosis, GTF2A1L wt Allele, Cessation of life, Liver Failure, Acute	Altered Intercellular Communication	Acute liver failure (ALF) is characterised by overwhelming hepatocyte death and liver inflammation with massive infiltration of myeloid cells in necrotic areas.	28450389
Acute inflammation	Altered Intercellular Communication	The mechanisms underlying resolution of acute hepatic inflammation are largely unknown.	28450389
Inflammation, GTF2A1L wt Allele, Injury of liver	Altered Intercellular Communication	Compared with WT mice which show an increase of MerTK+MHCIIhigh macrophages during the resolution phase in ALF, APAP-treated Mer-/- mice exhibit persistent liver injury and inflammation, characterised by a decreased proportion of resident Kupffer cells and increased number of neutrophils.	28450389
Cluster, Observation Method - Coagulation, Inflammation	Altered Intercellular Communication	Cluster analysis of 20 biomarkers of inflammation, coagulation and endothelial activation provided the phenotypes in a training cohort, not taking any outcome data into account.	28450529
Inflammation, Comorbidity	Altered Intercellular Communication	However, switching to open surgery as well as increase of complications in patients who admitted with severe inflammation attack and who have high comorbidity, caution should be exercised when selecting patients for early operation.	28451027
hyperthermia treatment, Leukocytosis, Acute inflammation	Altered Intercellular Communication	We evaluated postoperative inflammation based on duration of hyperthermia (body temperature >=38 degC) and leukocytosis (>=12,000/uL-1).	28451762
Inflammation, Leukocytosis, hyperthermia treatment	Altered Intercellular Communication	The prolonged inflammation group comprised 57 (11.7%) patients who had hyperthermia for 4 days or longer and 42 (8.6%) patients who had leukocytosis for 7 days or longer.	28451762
Inflammation, Brain Injury, Chronic	Altered Intercellular Communication	We found that in MDA5+ DMIP, acute alveolar inflammation caused a poor prognosis early in the disease course, and in ARS+ DMIP, chronic injury to the alveolar epithelial cells or basement membrane caused long-term recurrence.	28451794
Airway structure, Coughing	Altered Intercellular Communication	Upper airway inflammation is one of the most commonly identified causes of chronic cough, although the underlying mechanism is not clear.	28452705
Gastrointestinal inflammation, Ulcerative Colitis	Altered Intercellular Communication	Pathogenic or protective functions of these cells during human intestinal inflammation, such as ulcerative colitis [UC], have not previously been defined, with understanding largely derived from animal model data.	28453768
Retinitis	Altered Intercellular Communication	Aberrant activation of the Wnt/b-catenin signaling pathway plays a pathogenic role in retinal inflammation and neovascularization.	28455497
Inflammation, Fibrosis Assessment, Pericarditis, CTCAE, Calcinosis	Altered Intercellular Communication	Idiopathic and postsurgical constrictive pericarditis is characterized by pericardial structural remodeling that involves fibrosis, calcification, and inflammation.	28456362
Inflammatory, Inflammation, Intestines, Crohn Disease	Altered Intercellular Communication	The sensitivity for detection of intestinal bowel thickening (a surrogate of inflammation) was 90%, and for detection of Crohn's disease complications, namely bowel stenosis and inflammatory mass, was 94% and 75%, respectively.	28457088
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Bowel ultrasound is a useful and feasible bedside imaging tool for the detection of inflammation and complications in IBD patients.	28457088
Inflammation, Pathology	Altered Intercellular Communication	This process increases the magnitude of inflammation and may influence the development of gastric pathologies.	28458166
Inflammation, Fibrosis Assessment, Stenosis, Pancreatitis	Altered Intercellular Communication	The underlying etiology of this case may have been the formation of a cicatricial stricture during the resolution of WON, in addition to fibrosis caused by the spreading of inflammation from pancreatitis.	28458308
vascular inflammations	Altered Intercellular Communication	Interleukin-10 (IL-10) plays a vital part in the pathophysiology of vascular inflammation.	28459600
Bethesda units, Inflammation, Inflammatory disorder, Uveitis	Altered Intercellular Communication	Birdshot Uveitis (BU) is an archetypical chronic inflammatory eye disease, with poor visual prognosis, that provides an excellent model for studying chronic inflammation.	28459868
Inflammation, Primary malignant neoplasm, Rheumatoid Arthritis, Cardiovascular Diseases	Altered Intercellular Communication	Human Leukocyte Antigen Shared Epitope and Inflammation, Cardiovascular Disease, Cancer, and Mortality Among Postmenopausal Women in the Women's Health Initiative Rheumatoid Arthritis Study.	28459968
Refractory anemias, Inflammation, Tenosynovitis	Altered Intercellular Communication	MRI-detected tenosynovitis was associated with RA development independent of other types of MRI-detected inflammation [odds ratio (OR) = 7.5, 95% CI: 2.4, 23] and also independent of age and other inflammatory measures (swollen joints, CRP) (OR = 4.2, 95% CI: 1.4, 12.9).	28460018
Lung Diseases, Obstructive, Syndrome	Altered Intercellular Communication	Radiographic Evidence of Sinonasal Inflammation in Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome: An Underrecognized Association.	28460847
ARCN1 gene, Inflammation, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Sinonasal inflammation on both clinical examinations and imaging significantly impacts both asthma and chronic obstructive pulmonary disease (COPD).	28460847
Inflammation, Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome	Altered Intercellular Communication	The objective of this study was to examine the association between sinonasal inflammation and asthma-COPD overlap syndrome (ACOS).	28460847
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	The frequency of radiographic evidence of sinonasal inflammation in patients with COPD, asthma, ACOS was 60.0%, 94.9%, and 72.2%, respectively.	28460847
ARCN1 gene, Inflammation, Asthma, levamisole	Altered Intercellular Communication	Patients with ACOS and COPD had only mild radiographic evidence of sinonasal inflammation (LMS score, 1-7), whereas moderate (LMS score, 8-11) and severe (LMS score, >=12) radiographic evidence of sinonasal inflammation were detected only in patients with asthma.	28460847
Inflammation, Comorbidity	Altered Intercellular Communication	Radiographic evidence of sinonasal inflammation was a common comorbidity in ACOS.	28460847
Exanthema, Inappropriate ADH Syndrome, Communicable Diseases, Encephalitis, herpesvirus 3, human, Acute cerebellar ataxia	Altered Intercellular Communication	We report a case of varicella-zoster virus (VZV) infection with acute cerebellitis and encephalitis with associated Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) in an elderly man presenting with acute cerebellar ataxia without antecedent rash.	28460866
Giant Cell Arteritis, Inflammation, GCA gene, Cutaneous Small Vessel Vasculitis	Altered Intercellular Communication	We investigated the diagnostic value of inflammation limited to the adventitia (ILA), and isolated vasa vasorum or small-vessel vasculitis (VVV, SVV) in temporal artery biopsies (TAB) for giant cell arteritis (GCA).	28461644
Inflammation, Dyslipidemias, Dental Plaque, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Ameliorating dyslipidemia in type 2 diabetic patients by femoropopliteal artery plaque resection under acute inflammation response.	28462578
Inflammation, "Alzheimers Disease", Cognition Disorders, Data types - Address	Altered Intercellular Communication	The role of inflammation in Alzheimer's disease (AD) and other cognitive disorders is unclear.	28464009
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	LBP was correlated with lobular inflammation (P=.001), while both LBP (P=.0004) and endotoxin levels (P=0.008) were correlated with fibrosis.	28464257
Inflammation	Altered Intercellular Communication	Epicardial fat causes inflammation and contributes to progression of CAD.	28464274
Meningitis	Altered Intercellular Communication	Spread/fill foci are associated with reduced cortical gray matter volumes and may represent blood-meningeal barrier breakdown near sites of meningeal inflammation, whereas nodular foci may be a normal variant.	28464368
Cerebrovascular, Inflammation, Psoriasis, Inflammatory disorder	Altered Intercellular Communication	Psoriasis is a multifactorial inflammatory disorder, in which the inflammation affects not only the skin but also the other internal organs, and can induce cardiovascular and cerebrovascular involvements.	28464401
Chronic frontal sinusitis, polyps, Sinusitis, Inflammation	Altered Intercellular Communication	Eosinophilic chronic frontal sinusitis is difficult to treat compared with non-eosinophilic sinusitis because of recurring inflammation and polyp formation in the frontal recess after the post-operative follow-up period.	28464955
Inflammation	Altered Intercellular Communication	Concomitantly, clinical parameters and serum markers of inflammation were found reduced.	28465139
Inflammation, Data types - Address	Altered Intercellular Communication	CD68 may play key roles in the pathogenesis of AD and its complications may be via induction of inflammation.	28465247
Inflammation	Altered Intercellular Communication	In the early postoperative period, the protein expression of inflammatory cytokines implicates that fibrin glue may induce accelerated healing and subdued inflammation on the ocular surface compared to sutures.	28465659
Neurodegenerative Disorders, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	Oxidative stress, a disturbance in the balance between oxidant/antioxidant ratios, is associated with cancer, aging, inflammation, neurodegenerative diseases and other conditions.	28466919
Inflammation	Altered Intercellular Communication	The SOFA, GOS, and inflammation factors were significantly better in the zinc-supplemented group by day 16 (all p < .05).	28467150
Osteogenesis, Inflammation, OSSIFICATION OF THE POSTERIOR LONGITUDINAL LIGAMENT OF SPINE	Altered Intercellular Communication	Serum biomarkers in patients with ossification of the posterior longitudinal ligament (OPLL): Inflammation in OPLL.	28467440
Inflammation, OSSIFICATION OF THE POSTERIOR LONGITUDINAL LIGAMENT OF SPINE	Altered Intercellular Communication	The results may suggest the occurrence of local inflammation in OPLL and the inflammation might cause OPLL progression.	28467440
Malignant tumor of colon, Inflammation	Altered Intercellular Communication	The occurrence and development of colon cancer is closely related to inflammation.	28467774
Inflammation, Fibrosis Assessment, Granulomatous inflammation	Altered Intercellular Communication	Soft tissue reactions to paraffin include inflammation, fibrosis, disfigurement, and granulomatous inflammation with foreign body giant cell reaction.	28468169
Necrotizing granulomatous inflammation, Bacterial Infections, Actinomycosis	Altered Intercellular Communication	Actinomycosis, an infectious bacterial disease caused by Actinomyces species, is very rare and is characterized by contiguous spreading, subacute to chronic granulomatous inflammation and the formation of multiple abscesses and sinus tracts that may discharge sulfur granules.	28468217
Aneurysm, Inflammation	Altered Intercellular Communication	Histology revealed evidence for a true aneurysm without overt, acute, or chronic inflammation of the surrounding gastric mucosa.	28468689
Cerebral Small Vessel Diseases, Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	In the brain, enlarged perivascular spaces (PVS) relate to cerebral small vessel disease (SVD), poor cognition, inflammation and hypertension.	28468952
Mammary Neoplasms	Altered Intercellular Communication	To address this paradox, we evaluated relation between IL17A and IL32 expression and other inflammation- and T cell response-associated genes in breast tumors.	28470472
Inflammation, Juvenile-Onset Still Disease	Altered Intercellular Communication	Adult-onset Still's disease (AOSD) is characterized by multiple systemic inflammation of unknown etiology.	28470759
Degenerative polyarthritis, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Ultrasonography-detected subclinical inflammation in patients with hand osteoarthritis and established rheumatoid arthritis: a comparison between two different pathologies using the same ultrasound examination protocol.	28471034
Degenerative polyarthritis, Joint swelling, Synovial Hypertrophy, Refractory anemias	Altered Intercellular Communication	Subclinical joint inflammation in the context of equivocal clinical examination was found in 9.6% of OA patients compared with 46.4% of RA patients (p = 0.0001), despite the fact that there was no significant difference between the degree of chronic joint swelling (synovial hypertrophy grades 2 and 3; p = 0.75 and p = 0.11, respectively).	28471034
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	Our study findings reflected differences between the incidence and characteristics of subclinical inflammation in patients with RA and OA, which could be helpful in patients with an equivocal clinical examination or history of both diseases.	28471034
Degenerative polyarthritis, Inflammation, Synovitis, Refractory anemias	Altered Intercellular Communication	Almost one in 10 patients with hand OA had active synovitis, while almost one in two patients with RA had uncontrolled inflammation in at least one joint.	28471034
Inflammation, Vascular Diseases	Altered Intercellular Communication	Galectin-3 is a modulator of oxidative stress, inflammation, and fibrogenesis involved in the pathogenesis of vascular diseases.	28471381
Lupus Erythematosus, Systemic	Altered Intercellular Communication	This has led to the proposal of a hormonal role in the development of SLE.	28471600
Inflammation, Brain hemorrhage	Altered Intercellular Communication	Postmortem pathologic analysis revealed aspergillus-associated inflammation of blood vessels and ischemic and petechial hemorrhagic strokes in the affected territories.	28471899
Communicable Diseases, Inflammation, Infection	Altered Intercellular Communication	Infections represented 82.6% of all cases with a leukocyte count >100 x 10/L whereas 56.3% of cases with at leukocyte counts <100 x 10/L were dominated by disease not related to infection.The present study may serve as a reminder to clinicians of what diseases and disease categories to suspect when patients present with CSF biochemistry indicating CNS inflammation.	28471963
Infection	Altered Intercellular Communication	Infections were the most common cause of CSF pleocytosis (61.4%) followed by miscellaneous causes (12.7%), vascular (9.7%), neurodegenerative (7%), neoplastic (5%), and inflammatory conditions (4.2%).	28471963
Chronicity, Inflammation, Inflammatory Bowel Diseases, Pulmonary Dysfunction	Altered Intercellular Communication	The chronicity of inflammation might probably reduce the possibility of developing pulmonary dysfunction, while the erythrocyte sedimentation rate (ESR) was found as a harmful factor for developing pulmonary dysfunction.The pulmonary function significantly decreases in IBD patients and is characterized by either simple restrictive/obstructive dysfunction or mixed.	28471982
Inflammation, Aggressive behavior, Macrophage Chemotactic Factors	Altered Intercellular Communication	Additionally, prolonged exposure of MCF cells to IL6 or IL8 induced the appearance of senescent cells, suggesting a mechanism by which senescence and inflammation are reinforced favouring the acquisition of EMT and stem-like features at the population level, thus increasing tumour aggressiveness.	28472950
Intraocular inflammation	Altered Intercellular Communication	The macular hole was managed with macular hole surgery after intraocular inflammation had resolved.	28473358
Inflammation, Atherosclerosis	Altered Intercellular Communication	Human Plasma Thioredoxin-80 Increases With Age and in ApoE-/- Mice Induces Inflammation, Angiogenesis, and Atherosclerosis.	28473446
Inflammation, Congenital Abnormality	Altered Intercellular Communication	The correlations observed indicate that lipids abnormalities, inflammation, and oxidative stress may be involved in this destructive process.	28473982
Inflammation, Perivascular inflammation	Altered Intercellular Communication	Vascular and/or perivascular involvements of sclerotic inflammation (perivasculitis) are a complication of immunoglobulin G4-related disease (IgG4-RD).	28474137
Airway structure, Asthma	Altered Intercellular Communication	Here, we evaluated the frequencies and activation status of basophils in the sputum of adult asthmatic patients and related our findings to other parameters of eosinophilic airway inflammation.	28474352
Airway structure, Asthma	Altered Intercellular Communication	A trial of oral corticosteroids for persistent systemic and airway inflammation in severe asthma.	28474411
Inflammation, Asthma	Altered Intercellular Communication	The fraction of exhaled nitric oxide (FeNO) and blood eosinophils, markers of local and systemic eosinophilic inflammation, respectively, are increased in asthmatic patients.	28474411
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Activation of renin-angiotensin-aldosterone and endothelin systems plays a key role in endothelial dysfunction, vascular remodelling, and aging by inducing reactive oxygen species production, and promoting inflammation and cell growth.	28474545
Inflammation, Nasal Polyps, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) is characterized by type 2 inflammation with high levels of Th2 cytokines.	28474861
Inflammation	Altered Intercellular Communication	These results suggest that ILC2 are not only elevated but also activated in CRSwNP in vivo and that ILC2 may play important roles in the type 2 inflammation in CRSwNP.	28474861
Inflammation, Hyperpigmentation	Altered Intercellular Communication	Clinically, 3 main distinct types of hyperpigmentation by minocycline have been distinguished: type I, with blue-gray to black pigment on the face in areas of scarring or inflammation; type II, with blue-gray pigment on normal skin of the legs, forearms and on the shins; and type III, with a diffuse muddy-brown discoloration in areas of sun exposure.	28475520
Inflammation, Fibrosis Assessment, Chronic infectious disease	Altered Intercellular Communication	We evaluated the diagnostic usefulness of these markers in hepatic fibrosis and inflammation of patients with chronic viral infection.	28475652
Inflammation, Traumatic injury	Altered Intercellular Communication	Experimental studies suggest that mechanical cell washing to remove pro-inflammatory components that accumulate in the supernatant of stored donor red blood cells (RBCs) might reduce inflammation and organ injury in transfused patients.	28475670
Inflammation, Obesity, Visceral, Metabolic Syndrome X, Hyperglycemia, Malignant neoplasm of gastrointestinal tract	Altered Intercellular Communication	Visceral obesity and metabolic syndrome (MetSyn) represent a constellation of inflammation, insulin resistance, and hyperglycemia and are established risk factors for gastrointestinal cancer.	28475745
Inflammation	Altered Intercellular Communication	Systematic review of the literature illustrated high consistency in the association between these biomarkers of inflammation and renal outcomes in DKD.	28476763
Fibrosis Assessment, Liver damage, Hepatitis	Altered Intercellular Communication	The marker seems to reflect not only liver fibrosis but also other factors, such as liver inflammation, liver damage, and hepatocyte regeneration.	28477171
Inflammation, Data types - Address	Altered Intercellular Communication	Inflammation is frequently related to AD, whereas microglial cells are the major phagocytes in the brain and mediate the removal of Ab peptides.	28477215
Inflammation, Schizophrenia	Altered Intercellular Communication	A molecular pathway analysis stresses the role of inflammation and oxidative stress towards cognition in schizophrenia.	28477285
Inflammation	Altered Intercellular Communication	We report that inflammation and in particular the pathway associated with arachidonic acid was enriched in mutations associated with poorer performance at the verbal memory and working memory tasks in SKZ patients.	28477285
Inflammation, Vascular Diseases, Erysipelas, Lichen Sclerosus et Atrophicus, Alcohol abuse	Altered Intercellular Communication	The diagnosis of ACA is often clinically missed for months or years, and may be mistaken at the inflammation phase for vascular disorders, erysipelas or bursitis/arthritis, and at the atrophic phase for lichen sclerosus atrophicus, morphoea or anetoderma.	28477365
Inflammation	Altered Intercellular Communication	Nutritional support and resistance training were shown to increase muscle anabolism and reduce inflammation in healthy elderly.	28477944
Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	We hypothesized that nutritional support and resistance training would accelerate the resolution of inflammation in hospitalized elderly patients with SIRS.	28477944
Inflammation, "Marjolins ulcer	Altered Intercellular Communication	A known risk factor for cSCC is chronic inflammation; a cSCC that develops at a site of chronic inflammation is known as Marjolin's ulcer.	28478388
Communicable Diseases, Inflammation	Altered Intercellular Communication	Suppurative inflammation was observed in 1 patient, and infection occurred after bone reposition.	28479048
Tumor necrosis, Inflammation	Altered Intercellular Communication	Toll-like receptor 3 (TLR3) is involved in type I interferon-b (IFN-b) via TIR-domain-containing adapter-inducing interferon-b (TRIF) and Tumor necrosis factor receptor-associated factor 3 (TRAF3), culminating in inflammation and immunity reactions.	28479387
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Cerebral Granulomatous Inflammation Secondary to Hydrophilic Polymer Embolization Following Thrombectomy.	28479590
Inflammation, Trachoma	Altered Intercellular Communication	trachomatous inflammation, follicular and/or intense, indicative of active trachoma.	28479620
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Aerobic exercise improves quality of life, psychological well-being and systemic inflammation in subjects with Alzheimer's disease.	28479898
Inflammation	Altered Intercellular Communication	Cardamom could improve some parameters of inflammation and oxidative stress in pre-diabetic subjects.	28480505
Inflammation	Altered Intercellular Communication	Thus it may be useful in reducing complications associated with inflammation and oxidative stress in these patients.	28480505
Inflammation	Altered Intercellular Communication	The purpose of this study was to quantify multifidus tissue composition and structure, inflammation, vascularity, and degeneration in individuals with chronic degenerative lumbar spine pathology.	28480978
Inflammation, Muscle degeneration, Muscle Fibers, Slow-Twitch	Altered Intercellular Communication	Relative fractions of muscle, adipose, and extracellular matrix were quantified along with muscle fiber type and cross-sectional area (CSA) and markers of inflammation, vascularity, satellite cell density, and muscle degeneration.	28480978
Inflammation, Muscle degeneration	Altered Intercellular Communication	High levels of muscle degeneration, inflammation, and decreased vascularity were commonly seen in human multifidus biopsies of individuals with lumbar spine pathology in comparison to normative data.	28480978
Inflammation, Acute inflammation	Altered Intercellular Communication	C1M (71.2+-26.1 vs 46.2+-6.2 nmol/L [P<.001]), C3M (31.6+-3.9 vs 26.1+-1.6 nmol/L [P=.002] and Pro-C5 levels (1171.7+-171.5 vs 909.6+-80.4 nmol/L [P=.002]) were higher in patients with active inflammation vs without active inflammation.	28481042
Inflammation, Crohn Disease	Altered Intercellular Communication	Active inflammation in Crohn's disease is characterised by increased formation of type V collagen and increased matrix metalloproteinase mediated breakdown of type I, III collagen.	28481042
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Systemic inflammation is an integral part of chronic obstructive pulmonary disease (COPD), and air pollution is associated with cardiorespiratory mortality, yet the interrelationships are not fully defined.	28481326
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	These findings raise the possibility that the interplay between air pollution and systemic inflammation may differ between post-BD airflow obstruction and cardiovascular diseases.	28481326
Communicable Diseases, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Multiple-Breath Washout Outcomes Are Sensitive to Inflammation and Infection in Children with Cystic Fibrosis.	28481640
Communicable Diseases, Upper Respiratory Infections, Cystic Fibrosis	Altered Intercellular Communication	The lung clearance index is increased in the presence of lower respiratory tract inflammation and infection in infants with cystic fibrosis; however, the associations during the preschool years are unknown.	28481640
Communicable Diseases, Upper Respiratory Infections, Cystic Fibrosis	Altered Intercellular Communication	We assessed the ability of the lung clearance index to detect the presence and extent of lower respiratory tract inflammation and infection in preschool children with cystic fibrosis.	28481640
Communicable Diseases, Fibrosis Assessment	Altered Intercellular Communication	Children with cystic fibrosis also underwent bronchoalveolar lavage fluid collection for detection of lower respiratory tract inflammation and infection.	28481640
Airway structure, Fibrosis Assessment, Respiratory Tract Infections	Altered Intercellular Communication	In cystic fibrosis, the lung clearance index was elevated in individuals with lower respiratory tract infections (difference compared with uninfected [95% confidence interval], 0.62 [0.06, 1.18]) and correlated with the extent of airway inflammation.	28481640
Airway structure, Communicable Diseases, Cystic Fibrosis	Altered Intercellular Communication	These data suggest that the lung clearance index may be a useful surveillance tool for monitoring the presence and extent of lower airway inflammation and infection in preschool children with cystic fibrosis.	28481640
Intraocular inflammation	Altered Intercellular Communication	Improvement in intraocular inflammation was seen in all 24 eyes, with median best-corrected visual acuity (BCVA) increasing from 20/50 to 20/20, after a mean follow-up of 5.3 months.	28481679
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Limited prospective data have been reported regarding the impact of carotid inflammation on cardiovascular events in patients with coronary artery disease (CAD).	28482222
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Microglial dysfunction and inflammation have recently been shown to be related to the development of Alzheimer's disease (AD).	28482637
neutrophilic, Inflammation, Bacterial Infections	Altered Intercellular Communication	Bacterial infection may influence corticosteroid responsiveness by altering the profile of neutrophilic and eosinophilic inflammation.	28482840
Inflammation, Neoplasms	Altered Intercellular Communication	Systemic inflammation and nutritional status are strongly associated with tumor progression.	28483664
Malignant Neoplasms	Altered Intercellular Communication	Inflammation-based prognostic scores, such as the Glasgow Prognostic Score (GPS), reflect these states and are predictive in patients with several types of advanced cancers.	28483664
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Last, modulation of target organ inflammation (eg, skin) was associated with an improvement in NCB at 1 year, suggesting that control of remote sites of inflammation may translate into reduced coronary artery disease risk.	28483812
Chronic infectious disease, Inflammation	Altered Intercellular Communication	Chronic infection and associated inflammation have long been suspected to promote human carcinogenesis.	28483840
Inflammation, CEL gene, Polyneuropathy	Altered Intercellular Communication	The relationship between familial amyloid polyneuropathy (FAP), which is caused by mutated transthyretin (TTR), and inflammation has only recently been noted.	28484271
Inflammation, CEL gene	Altered Intercellular Communication	In conclusion, FAP carriers and patients are in an inflammatory state, with the presence of mutated TTR being a trigger of inflammation, especially in FAP carriers.	28484271
Inflammation, Necrosis	Altered Intercellular Communication	The induced inflammation and necrosis after CRT were also investigated.	28485348
Nasal Polyps, Chronic sinusitis, Helper-Inducer T-Lymphocyte	Altered Intercellular Communication	P-glycoprotein (P-gp) drives type-2 helper T-cell inflammation in chronic rhinosinusitis with nasal polyps (CRSwNP) through unknown posttranslational mechanisms of overexpression.	28485529
Arthritis, Gout	Altered Intercellular Communication	Gout commonly involves joint inflammation, and clinical epidemiological studies on involved tendons are scant.	28486089
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Depressive symptom profiles, cardio-metabolic risk and inflammation: Results from the MIDUS study.	28486177
Inflammation	Altered Intercellular Communication	Our results suggested that a local pulmonary administration of heparin through nebulization may be able to reduce inflammation in the lung; however, further studies are needed to confirm this hypothesis.	28486961
Atrial Fibrillation, Acute inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Atrial fibrillation (AF) is the most frequent complication of surgery performed on cardiopulmonary bypass (CPB) and recent work associates CPB with postoperative inflammation.	28487062
Inflammation	Altered Intercellular Communication	If mtDNA is directly involved in cardiac inflammation, mtDNA-induced toll-like receptor-9 (TLR9) signalling could also be targeted therapeutically.	28487062
Inflammation, Pneumonia	Altered Intercellular Communication	The diagnosis of pneumonia was based on radiological evidence of chest inflammation and clinical symptoms.	28487142
Inflammation	Altered Intercellular Communication	The chemokine receptor CCR5 plays roles in the trafficking of effector cells towards the site of inflammation.	28487238
Prostate carcinoma, prostatitis	Altered Intercellular Communication	However, their effect on histologic prostate inflammation is not well understood, particularly among men at increased prostate cancer risk but with a negative prostate biopsy.	28487295
Inflammation, Acute inflammation	Altered Intercellular Communication	Statin users had reduced presence of chronic inflammation (OR, 0.81; 95% CI, 0.69-0.95) and were less likely to have severe chronic (OR, 0.80; 95% CI, 0.68-0.95) and severe acute inflammation (OR, 0.73; 95% CI, 0.53-1.00), relative to non-users.	28487295
Inflammation, Prostate carcinoma, prostatitis	Altered Intercellular Communication	Given the possible role for inflammation in prostate cancer, the inverse association between statins and prostate inflammation suggests a mechanism linking statins with lower advanced prostate cancer risk.	28487295
Inflammation, Dental Plaque	Altered Intercellular Communication	Inflammation and intraplaque neovascularization are acknowledged to be 2 features of plaque vulnerability, although their temporal expression and their respective value in predicting clinical events are poorly understood.	28487317
Inflammation, Dental Plaque	Altered Intercellular Communication	To determine their respective temporal associations, we conducted a comprehensive assessment of inflammation and intraplaque neovascularization in the carotid plaque of symptomatic and asymptomatic patients.	28487317
Inflammation	Altered Intercellular Communication	Plaque 18F-fluorodeoxyglucose-uptake, indicative of inflammation, was measured by calculating the target:background ratio.	28487317
Inflammation, Dental Plaque	Altered Intercellular Communication	Inflammation and intraplaque neovascularization are not systematically associated in carotid plaques, suggesting a temporal separation between the 2 processes.	28487317
Refractory anemias, leukemia	Altered Intercellular Communication	CONCLUSIONS While anti-CD20 antibodies have a clear role in the treatment of leukemia and inflammatory conditions, the success of obinutuzumab in RA has not been fully evaluated.	28487504
Inflammation, Imprinting (Psychology), Obesity	Altered Intercellular Communication	The maternal inflammation status during pregnancy has been associated with metabolic imprinting and obesity development in the child.	28487553
Cholangiocarcinoma, Biliary Intraepithelial Neoplasia	Altered Intercellular Communication	Biliary intraepithelial neoplasia (BilIN) is a precursor of cholangiocarcinoma (CC) and it has been associated with several chronic inflammatory conditions.	28490009
Inflammation, Brain Injuries	Altered Intercellular Communication	Targeting peripherally derived, or resident inflammatory, cells that are rapid responders to brain injury is promising, but complex, given that the contribution of inflammation to exacerbation versus improved recovery varies with time post-injury.	28490277
Crohn Disease, Inflammation	Altered Intercellular Communication	Crohn's Disease (CD) is a relapsing inflammation of the gastrointestinal tract that affects a young working age population and is increasing in developing countries.	28490445
Inflammatory Bowel Diseases, Inflammation, Rheumatoid Arthritis, Ulcerative Colitis	Altered Intercellular Communication	DAVID 6.7 (NIH) was used for functional annotation analysis of detected proteins and immunoblotting and multiple reaction monitoring (MRM) to verify a priori findings in a secondary independent cohort of complicated CD (CCD), uncomplicated inflammatory CD (ICD), Th1/17 pathway inflammation controls (rheumatoid arthritis), inflammatory bowel disease controls (ulcerative colitis), and healthy controls.	28490445
Inflammation, Torsades de Pointes	Altered Intercellular Communication	Systemic inflammation as a novel QT-prolonging risk factor in patients with torsades de pointes.	28490617
Inflammation, Long QT Syndrome	Altered Intercellular Communication	Increasing evidence indicates systemic inflammation as a new potential cause of acquired long QT syndrome (LQTS), via cytokine-mediated changes in cardiomyocyte ion channels.	28490617
Inflammation, TDP biosynthetic process	Altered Intercellular Communication	Since classical risk factors cannot fully explain TdP events in a number of patients, we hypothesised that systemic inflammation may represent a currently overlooked risk factor contributing to TdP development in the general population.	28490617
Inflammation, TDP biosynthetic process	Altered Intercellular Communication	The data are first to show that systemic inflammation via elevated IL-6 levels may represent a novel QT-prolonging risk factor contributing to TdP occurrence in the presence of other classical risk factors.	28490617
Inflammation	Altered Intercellular Communication	In conclusion, elevated WBC counts independently predict the risk of new-onset PAD in a Chinese community-based population, supporting the hypothesis that systemic inflammation plays an important role in PAD development.	28490753
Airway structure, ARCN1 gene	Altered Intercellular Communication	Interleukin (IL)-1b and IL-17 are the key mediators of neutrophilic airway inflammation in COPD.	28490868
Airway structure, ARCN1 gene	Altered Intercellular Communication	In conclusion, elevated serum IL-1b and IL-17 levels may be used as a biomarker for indicating persistent neutrophilic airway inflammation and potential ongoing exacerbation of COPD.	28490868
Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Measurements of eosinophils in induced sputum and fractional exhaled nitric oxide (FeNO) are noninvasive biomarkers for assessing airway inflammation phenotypes in chronic obstructive pulmonary disease (COPD).	28490872
Inflammation, Chronic gastritis	Altered Intercellular Communication	Curcumin can be a useful supplement to improve chronic inflammation and prevention of carcinogenic changes in patients with chronic gastritis associated by H. pylori.	28492711
Psoriatic Juvenile Idiopathic Arthritis, Inflammation	Altered Intercellular Communication	Recent studies indicate the presence of systemic inflammation in psoriatic patients, and this inflammatory status is significantly associated with a range of comorbidities.	28493493
Inflammation, Arthritis	Altered Intercellular Communication	MPV value was negatively associated with the presence of arthritis, but its association with inflammation was less clear than that of NLR or PLR.	28493493
Psoriatic Juvenile Idiopathic Arthritis, Inflammation	Altered Intercellular Communication	Altogether, these results indicate that both NLR and PLR may be useful markers to evaluate systemic inflammation in psoriatic patients.	28493493
Arthralgia, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	SP and NK1 receptors have been implicated in joint pain, inflammation and damage in animal models and human studies of osteoarthritis (OA).	28493529
Inflammation	Altered Intercellular Communication	Genomic biomarkers of prenatal intrauterine inflammation in umbilical cord tissue predict later life neurological outcomes.	28493900
Inflammation	Altered Intercellular Communication	Genes that were differentially expressed across four indicators of intrauterine inflammation were identified and their functions examined.	28493900
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Postmenopausal status could predict MetS, with inflammation and oxidative stress arising from an unhealthy lifestyle potentially increasing cardiovascular risk.	28494104
Pain Distress Question, Diabetic dermopathy, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Influence of low-level laser on pain and inflammation in type 2 diabetes mellitus with diabetic dermopathy - A case report.	28494177
Inflammation, Chronic sinusitis, Craniosynostosis, Dysbiosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by persistent sinonasal inflammation and sinus microbiome dysbiosis.	28494786
Inflammation, Postexertional fatigue, Anxiety, CTCAE 3.0, Depression, CTCAE, Fatigue	Altered Intercellular Communication	Clinical markers consisted of questionnaire scores for symptoms of post-exertional malaise, inflammation, fatigue, depression and trait anxiety, as well as activity recordings.	28494812
Inflammation, B-Cell Differentiation	Altered Intercellular Communication	Gene set enrichment analyses suggested impairment of B cell differentiation and survival, as well as enhancement of innate antiviral responses and inflammation in the CFS group.	28494812
Inflammation, B-Cell Differentiation, Chronic Fatigue Syndrome	Altered Intercellular Communication	Adolescent CFS is characterized by differential gene expression pattern in whole blood suggestive of impaired B cell differentiation and survival, and enhanced innate antiviral responses and inflammation.	28494812
Refractory anemias, Rheumatoid Arthritis, Arthritis, Autoimmune Diseases	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a systemic autoimmune disease whose main feature is persistent joint inflammation.	28495399
Inflammation	Altered Intercellular Communication	Toll-like receptors (TLRs) play critical roles in the activation of innate and adaptive immune responses, and influence the activity of NFkB, a key player in chronic inflammation.	28495399
Inflammation, Hemorrhage, Dental Plaque	Altered Intercellular Communication	There was no significant difference in probing depth, peri-implant inflammation, bleeding, and plaque between the two groups (p > 0.05), while the calculus was significantly more observed in ISCRPD group than in IARPD group (p < 0.05).	28497062
Inflammation, Dental Plaque	Altered Intercellular Communication	Chitosan brush could be a reliable instrument for the professionally administered plaque removal and resolution of clinical signs of initial stages of peri-implant inflammation.	28497660
Inflammation, Bronchiectasis, Tissue damage, Communicable Diseases, Malignant Neoplasms	Altered Intercellular Communication	The spectrum of pulmonary manifestations in PIDs is broad, and includes acute and chronic infection, structural abnormalities (eg, bronchiectasis), malignancy and dysregulated inflammation resulting in tissue damage.	28497675
Inflammation, Psoriasis	Altered Intercellular Communication	Serum YKL-40 as a potential biomarker of inflammation in psoriasis.	28498006
Psoriatic Juvenile Idiopathic Arthritis, Inflammation, Psoriasis	Altered Intercellular Communication	YKL-40 might be a biomarker of psoriasis and inflammation in psoriatic patients, but not a reliable indicator of metabolic conditions, severity of psoriasis nor efficacy of the treatment.	28498006
Inflammation, Clear cell adenocarcinoma of ovary	Altered Intercellular Communication	Prognostic significance and predictors of the system inflammation score in ovarian clear cell carcinoma.	28498842
Association of Community Cancer Centers, Inflammation, Adenocarcinoma, Clear Cell	Altered Intercellular Communication	Chronic inflammation is a well-known epidemiologic factor of ovarian clear cell carcinomas (OCCC), but has an uncertain role in prognosis.	28498842
Association of Community Cancer Centers, Inflammation	Altered Intercellular Communication	We developed a systemic inflammation score (SIS) based on preoperative serum albumin and neutrophil-to-lymphocyte ratio (NLR) for predicting progression-free survival (PFS) and overall survival (OS) in OCCC patients.	28498842
Association of Community Cancer Centers, Inflammation	Altered Intercellular Communication	We have developed a system inflammation score for predicting prognosis of OCCC patients, which may help stratify patients for postsurgical management.	28498842
Intraocular inflammation	Altered Intercellular Communication	After an 8- to 10-week hiatus, they were switched over to ranibizumab and aflibercept, respectively, following which they developed a second episode of intraocular inflammation, treated similarly.	28499055
Inflammation, Acute heart failure	Altered Intercellular Communication	Prealbumin is a maker of nutritional status and inflammation of potential prognostic value in acute heart failure (HF).	28499710
Inflammation, physiopathological, Nerve Degeneration	Altered Intercellular Communication	The factors associated with tau in serum may promote neurodegeneration and alter the permeability of the Blood Brain Barrier through chronic inflammation and vascular dysfunction.	28499950
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Immunological activity and vascular inflammation during atherosclerosis can be modulated by autoimmune responses against self-antigens, according to changeable risk factors (cholesterol, oxidized low-density lipoprotein (ox-LDL) in the vascular wall, fatty acids, etc.	28500763
Anorexia Nervosa, Amenorrhea	Altered Intercellular Communication	To measure, for the first time, serum kisspeptin concentrations in adolescent females with anorexia nervosa (AN) and associated amenorrhea, and investigate potential correlations of kisspeptin with anthropometric, bone and hormonal data.	28500826
Thyroid dysfunction, Autoimmune Thyroid Disease Pathway	Altered Intercellular Communication	Thyroid dysfunction affects the skeleton, and autoimmune thyroid disease, manifesting as a chronic inflammatory condition, may be an important contributing factor to impaired bone quality in these patients.	28500828
Inflammation, AHSG protein, human	Altered Intercellular Communication	Fetuin-A and adiponectin, major hepatokine and adipokine respectively, have been implicated in systematic inflammation.	28500919
Inflammation, Neoplasms	Altered Intercellular Communication	Gelatinases, Matrix MetalloProteinase(MMP)-2 and MMP-9, belong to zinc-dependent endopeptidases involved in several physiological and pathological processes including inflammation and tumor development.	28500926
Edema of eyelid, Inflammation, Orofacial Pain	Altered Intercellular Communication	Her main symptoms were orofacial pain, eye redness, inflammation of the eyelids, and eyelid edema.	28501097
Inflammation, Virus Diseases	Altered Intercellular Communication	While most human T cells express the CD28 costimulatory molecule constitutively, it is well known that age, inflammation, and viral infection can drive the generation of CD28null T cells.	28502091
Inflammation, Bronchiectasis	Altered Intercellular Communication	Systemic inflammation in bronchiectasis is poorly studied in relation to aetiology and severity.	28502416
Inflammation, Bronchiectasis	Altered Intercellular Communication	We hypothesized that molecular patterns of inflammation may define particular aetiology and severity groups in bronchiectasis.	28502416
Unknown (origin) (qualifier value), Post-infectious disorder, Inflammation	Altered Intercellular Communication	There were generally similar patterns of inflammation in patients with idiopathic and post-infectious disease.	28502416
Acute inflammation	Altered Intercellular Communication	We hypothesized that high-dose sodium selenite supplementation can attenuate the postoperative inflammation and might, therefore, improve clinical outcome.	28502744
Inflammation, Peripheral muscle fatigue	Altered Intercellular Communication	Peripheral muscle fatigue in hospitalised geriatric patients is associated with circulating markers of inflammation.	28502777
Inflammation, Obesity	Altered Intercellular Communication	Flavonoid intake is inversely associated with obesity and C-reactive protein, a marker for inflammation, in US adults.	28504712
Blindness, Inflammation, Uveitis	Altered Intercellular Communication	Uveitis, defined as inflammation of the uveal tract, may cause blindness in both young and middle-aged people.	28505077
Obesity	Altered Intercellular Communication	Obesity is associated with metabolic and hormonal dysregulation as well as adipokines increase.	28505082
Inflammation, Atrophic	Altered Intercellular Communication	Inflammation, Amyloid, and Atrophy in The Aging Brain: Relationships with Longitudinal Changes in Cognition.	28505968
Inflammation, Cerebral atrophy	Altered Intercellular Communication	Our results suggest a role for inflammation in brain atrophy and cognitive changes in cognitively normal older adults, which partly depended on Ab accumulation.	28505968
Genus Mycobacterium, Inflammation, Infection	Altered Intercellular Communication	An association between pulmonary Mycobacterium avium-intracellulare complex infections and biomarkers of Th2-type inflammation.	28506264
Inflammation, Ichthyosis Bullosa of Siemens, Irritable Bowel Syndrome	Altered Intercellular Communication	A growing body of evidence suggests a possible role for low-grade inflammation in the pathogenesis of irritable bowel syndrome (IBS).	28506572
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Increased inflammation biomarkers plasma levels, including C-reactive protein (CRP), have been associated with the initiation and perpetuation of atrial fibrillation (AF).	28506639
Inflammation	Altered Intercellular Communication	However, it is not known whether an increased CRP plasma level, without concomitant inflammation, is sufficient to induce AF.	28506639
Tubulointerstitial fibrosis, Nephritis, diabetic	Altered Intercellular Communication	Lysophosphatidic acid (LPA) and lysophosphatidylcholine (LPC) are lysophospholipid mediators shown to accumulate in kidney and to promote renal inflammation and tubulo-interstitial fibrosis in diabetic rodent models.	28506691
Tubulointerstitial fibrosis, Kidney damage, Nephritis, Diabetes Mellitus	Altered Intercellular Communication	Because LPA and LPC are known to promote renal inflammation and tubulo-interstitial fibrosis, their increased production in DN could participate to the development of kidney damage associated with diabetes.	28506691
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Unhealthy older octogenarians show increased levels of several plasma proteins of inflammation and coagulation.	28506697
Prostate carcinoma	Altered Intercellular Communication	Experimental studies have suggested that nonsteroidal anti-inflammatory drugs (NSAIDs) may improve prostate cancer survival through antithrombotic and anti-inflammation mechanisms.	28507039
vascular inflammations, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Non-alcoholic fatty liver disease, vascular inflammation and insulin resistance are exacerbated by TRAIL deletion in mice.	28507343
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Hepatic triglyceride content, inflammation and fibrosis were increased with TRAIL-deletion, with elevated expression of genes regulating lipogenesis and gluconeogenesis.	28507343
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In vitro, palmitate treatment of hepatocytes increased lipid accumulation, inflammation and fibrosis, with TRAIL mRNA significantly reduced.	28507343
vascular inflammations, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	These findings suggest that TRAIL protects against insulin resistance, NAFLD and vascular inflammation.	28507343
Inflammation, Obesity	Altered Intercellular Communication	Increased adipose tissue expression of IL-18R and its ligand IL-18 associates with inflammation and insulin resistance in obesity.	28508444
Inflammation, Fibrosis Assessment, Stenosis, Food impaction, "Extra-osseous Ewings sarcoma	Altered Intercellular Communication	Active inflammation (eosinophils >15 eos/high-power field), histological lamina propria fibrosis, and various features of a fibrotic phenotype (stricture, food impaction, circumferential rings on endoscopy) were associated with decreased distensibility within the EoE cohort.	28508868
Allergic asthma	Altered Intercellular Communication	We sought to characterize the involvement of NADPH oxidase in allergic asthma by studying the role of CYBA (p22phox) in human asthma and murine house dust mite (HDM)-induced allergic airway inflammation.	28510479
Refractory anemias, Inflammation, Degenerative polyarthritis	Altered Intercellular Communication	Regenerative medicine can be expected for RA patients with the inflammation well-controlled as well as OA patients and transplantation of synovial MSCs would also be a possible therapeutic treatment.	28511664
Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Endothelial dysfunction, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD) is a major risk factor for cardiovascular disease (CVD), partly due to endothelial dysfunction and chronic inflammation.	28511692
Inflammation, Chronic Kidney Diseases, Atherosclerosis	Altered Intercellular Communication	Paricalcitol treatment for 12 weeks in patients with moderate CKD reduces cytokines and micro RNAs involved in atherosclerosis and inflammation.	28511692
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Regulatory T cells (Tregs) play a role in the suppression of inflammation in autoimmune diseases, and lymphocyte activation gene 3 (LAG3) was reported as a marker of interleukin (IL)-10-producing Tregs.	28511719
Airway structure, Craniosynostosis, Asthma, Chronic sinusitis, Rhinitis	Altered Intercellular Communication	Despite the close linkage between rhinitis, chronic rhinosinusitis (CRS) and asthma, relevant biomarkers of both upper and lower airway inflammation are rare.	28513250
Herpes Simplex Infections, Granulomatous inflammation	Altered Intercellular Communication	Coexistence of herpes simplex virus infection in microsporidial stromal keratitis associated with granulomatous inflammation.	28513490
Herpes Simplex Infections, Granulomatous inflammation, Keratitis	Altered Intercellular Communication	Granulomatous inflammation, in microsporidial stromal keratitis, is never well described, and the authors in this article aim to describe the presence of granulomatous inflammation in microsporidial stromal keratitis, in patients with associated herpes simplex virus (HSV) keratitis.	28513490
Granulomatous inflammation	Altered Intercellular Communication	There was evidence of diffuse stromal necrosis with markedly severe degree of polymorphonuclear leukocytic infiltrates, with granulomatous inflammation in 42% of cases.	28513490
Granulomatous inflammation	Altered Intercellular Communication	Review of medical records revealed much severe clinical presentations in patients with granulomatous inflammation, in comparison to cases without granulomatous inflammation.	28513490
Granulomatous inflammation	Altered Intercellular Communication	The authors hereby recommend that severe clinical presentation in patients with microsporidial stromal keratitis, markedly dense polymorphonuclear leukocytic infiltrates or the presence of granulomatous inflammation on the histopathological examination, should be investigated further for the presence of HSV-1 DNA for better patient management and good visual outcome.	28513490
Tumor necrosis, Inflammation, Ascites, Malignant Neoplasms	Altered Intercellular Communication	Ascites with EOC cells also had higher levels of tumor necrosis factor (TNF)-a, suggesting inflammation related to the malignancy.	28513532
Inflammation	Altered Intercellular Communication	The mechanisms that enable preservation of gut mucosal integrity during persistent viral replication and inherent inflammation remain unclear.	28513595
niobium	Altered Intercellular Communication	No change in saliva hormonal concentrations was found during the experiment for both groups, whereas RPE responses were increased in the Good Ap group under Ap vs. NB conditions.	28514808
Brachydactyly, Midface retrusion, Intellectual Disability	Altered Intercellular Communication	His mother shared some characteristic features, such as midfacial hypoplasia and severe brachydactyly, but did not show short stature, intellectual disability or hormonal resistance.	28515031
Inflammation, Heart failure, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	Furthermore, anemia, insulin resistance, inflammation, and poor glycemic control are independent risk factors for the development of heart failure among patients with chronic kidney disease.	28515118
Hypocalciuria, Parathyroiditis, Hypercalcemia, CTCAE	Altered Intercellular Communication	Here, we describe a patient with acquired parathyroid hormone (PTH)-dependent hypercalcemia with associated hypocalciuria, found to have true lymphocytic parathyroiditis on histopathology, and circulating anti-CaSR antibodies in serum.	28515208
Inflammation, Pneumonia	Altered Intercellular Communication	The elderly, who manifest a general decline in immune function and higher basal levels of inflammation, are at increased risk of developing pneumococcal pneumonia.	28516066
Communicable Diseases, Pneumonitis, Pneumonia	Altered Intercellular Communication	Using an aged mouse infection model, we previously showed that oral supplementation with the alpha-tocopherol form of vitamin E (a-Toc) decreases pulmonary inflammation, in part by modulating neutrophil migration across lung epithelium into alveolar spaces, and reverses the age-associated decline in resistance to pneumococcal pneumonia.	28516066
Pneumonitis	Altered Intercellular Communication	We found that basal levels of pneumococcal-induced transepithelial migration by PMNs from young or elderly donors were indistinguishable, suggesting that the age-associated exacerbation of pulmonary inflammation is not due to intrinsic properties of PMNs of elderly individuals but rather may reflect the inflammatory milieu of the aged lung.	28516066
Rheumatoid Arthritis, Tenosynovitis	Altered Intercellular Communication	Tenosynovitis in rheumatoid arthritis patients on biologic treatment: involvement and sensitivity to change compared to joint inflammation.	28516887
Refractory anemias, Inflammation	Altered Intercellular Communication	Extensor carpi ulnaris (ECU) and tibialis posterior (TP) tendons are often involved in RA and the present aim was to examine by ultrasound (US) their frequency of inflammation and sensitivity to change in comparison to joint involvement as well as clinical examinations.	28516887
Pancreatic carcinoma	Altered Intercellular Communication	Together with the existing literature on this topic, our results suggest that reproductive and hormonal exposures are unlikely to play an important role in the etiology of pancreatic cancer.	28521283
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Depression, Inflammation, and Physiological Risk in Late Life: A National Longitudinal Study.	28521620
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Inflammation was indicated by C-reactive protein and depression by the CES-D scale.	28521620
Cessation of life	Altered Intercellular Communication	Family Member Deaths in Childhood Predict Systemic Inflammation in Late Life.	28521621
Inflammation	Altered Intercellular Communication	Biological and epidemiological evidence has linked early-life psychosocial stress with late-life health, with inflammation as a potential mechanism.	28521621
Cessation of life, Inflammation	Altered Intercellular Communication	We report here the association between familial death in childhood and adulthood and increased levels of high-sensitivity C-reactive protein (CRP), a marker of systemic inflammation.	28521621
Inflammation	Altered Intercellular Communication	The role of dietary antioxidants and plasma oxidant-antioxidant status in low-grade chronic inflammation and adipocytokine levels is not established yet.	28521871
Inflammation, effusion	Altered Intercellular Communication	Vascular permeability, effusions, inflammation, and other mechanisms may also play a role in the accumulation of radioactive iodine.	28522155
ARCN1 gene, Inflammation	Altered Intercellular Communication	In conclusion, oxidative stress reduces PTEN protein levels, which may result in increased PI3K signaling and amplification of inflammation in COPD.	28522564
Granulomatous inflammation, Infiltration	Altered Intercellular Communication	Biopsy of his left superficial temporal artery revealed a granulomatous inflammation with multinucleated giant cell infiltration, so he was diagnosed with GCA with consecutive left A-AION.	28523333
Retinal Degeneration, Intraocular inflammation	Altered Intercellular Communication	We retrospectively reviewed charts of patients without a family history of inherited retinal degenerations who presented with retinal pigment changes and signs of past or present intraocular inflammation.	28523457
Inflammation, Intraocular inflammation	Altered Intercellular Communication	Four of five cases presented with active inflammation, and the remaining case showed evidence of active intraocular inflammation during follow-up.	28523457
Inflammation, Uveitis	Altered Intercellular Communication	Careful review of possible past uveitis history, detailed examination of signs of past or present inflammation and ancillary testing, with FA often being most helpful, are required for the correct diagnosis.	28523457
Pigmentation, Inflammation	Altered Intercellular Communication	This is important, because intervention can prevent further damage if the cause of the pigmentary changes is destructive inflammation.	28523457
Infertility, Inflammation	Altered Intercellular Communication	Is male factor infertility associated with midlife low-grade inflammation?	28523952
Infertility, Inflammation	Altered Intercellular Communication	Male factor infertility is associated with an increased risk of disease and mortality, which has been related to markers of chronic systemic inflammation.	28523952
Inflammation	Altered Intercellular Communication	Inflammation was considered to play a role in the whole process of AS.	28524828
Acute inflammation, Hypertrophy, Enlarged kidney	Altered Intercellular Communication	We identified the ultrasound (US), magnetic resonance (MR), and CT-signs of acute renal inflammation at different stages of the process.The main us-signs were decreased mobility of the kidney, its enlargement, thickened parenchyma, hydrophilic parenchyma and an impairment of corticomedullary differentiation.The typical CT-signs of AP were enlargement of the kidney with its thickened parenchyma and an impairment of corticomedullary differentiation.The main MR-signs of AP were enlargement of the kidney (>12 cm lengthwise), thickened parenchyma (<2 cm in the median segment of the kidney) and an impairment of corticomedullary differentiation.	28525662
Intraocular inflammation, Fever	Altered Intercellular Communication	Two patients in cohort 4 (2 x 1010 vg) experienced adverse events that were possibly study-drug related: pyrexia and intraocular inflammation that resolved with a topical steroid.	28526489
Inflammation	Altered Intercellular Communication	Chronic inflammation plays an important role in AF development and interleukin-18 (IL-18) is a pro-inflammatory cytokine.	28526653
Inflammation, Ischemic stroke	Altered Intercellular Communication	Inflammation, kidney function, and frailty also seemed to be determinants of survival and recovery after an ischemic stroke.	28526765
Intraocular inflammation	Altered Intercellular Communication	This may be related to intraocular inflammation, which is more limited in chronic than in acute RRD.	28527031
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Many coronary artery disease (CAD) patients exhibit chronic low-grade inflammation.	28527371
Inflammation	Altered Intercellular Communication	Taken together, these results show that lutein has the potential to play a role in resolution of chronic inflammation in CAD patients.	28527371
Inflammation, "Alzheimers Disease", Memory impairment	Altered Intercellular Communication	Simvastatin ameliorate memory deficits and inflammation in clinical and mouse model of Alzheimer's disease via modulating the expression of miR-106b.	28528185
Inflammation, Impaired cognition, Presenile dementia, "Alzheimers Disease", Data types - Address, Brain Diseases	Altered Intercellular Communication	Alzheimer's disease (AD) as a neurodegenerative brain disorder is a devastating pathology leading to disastrous cognitive impairments and dementia, and several studies have shown that AD is closely related to the inflammation, so anti-inflammatory treatment may provide therapeutic benefits.	28528185
Inflammation, Chronic granulomatous disease, Mycoses	Altered Intercellular Communication	Chronic granulomatous disease (CGD) is characterized by recurrent life-threatening bacterial and fungal infections and aberrant inflammation.	28528201
Cachexia	Altered Intercellular Communication	Models were adjusted for case-mix and malnutrition-inflammation cachexia syndrome (MICS) covariates.	28528336
UGCG gene, Edema, Cardiac, Inflammation	Altered Intercellular Communication	Potentially, GCS might contribute to increased coronary vascular permeability in TTC, thus dissociating development of myocardial oedema from severity of associated inflammation.	28528983
Inflammation	Altered Intercellular Communication	Furthermore, obesity-induced inflammation, which affects UA metabolism and MCI onset, might regulate such protective role.	28529242
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	Microglial inflammation contributed to reduced FA in ALS, and may contribute to a pro-inflammatory state, but further work is needed to determine their role.	28529876
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The angiotensin II, through interaction with angiotensin II type 1 receptor (AGTR1), promotes proliferation, inflammation and fibrosis.	28530466
Inflammation, Milk, Human, Milk (body substance)	Altered Intercellular Communication	Controlling for age, inflammation, and other covariates, there was no difference in the mean pRBP, mean breast milk VA, prevalence of low pRBP, or prevalence of low milk VA between the pre- and post-fortification surveys.	28531099
Viral myocarditis, Inflammation	Altered Intercellular Communication	Diagnosis of viral myocarditis is difficult by clinical criteria but facilitated by detection of inflammation and viral genomes in endomyocardial biopsies.	28531186
Inflammation, Weight decreased, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Diet-induced weight loss and markers of endothelial dysfunction and inflammation in treated patients with type 2 diabetes.	28531772
Inflammation, Endothelial dysfunction, Obesity, Overweight, Weight decreased, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Diet-induced weight loss reduced the levels of biomarkers of endothelial dysfunction and inflammation in overweight and obese patients with T2D independently of medication use and T2D duration.	28531772
Inflammation, Obesity	Altered Intercellular Communication	The obesity and inflammation is associated with high REE and when not compensated by adequate intake, may determine an unfavorable clinical outcome in this population.	28531773
Inflammation, Neoplasm Metastasis, Malignant Neoplasms, Neoplasms	Altered Intercellular Communication	It has been shown that inflammation plays a major role in the treatment of these cancers and inflammatory factors enhance tumor growth, invasion, metastasis, and vascularization.	28532133
Perifolliculitis	Altered Intercellular Communication	Of 18,196 children aged 1-9 years examined, 1526 (8.4%) had trachomatous inflammation-follicular (TF).	28532208
ARCN1 gene, Inflammation	Altered Intercellular Communication	Besides the chronic inflammation in the lung compartment, there is also a systemic inflammation present in COPD patients.	28532454
Inflammation	Altered Intercellular Communication	This systemic inflammation is associated with elevated levels of cytokines in the peripheral blood, but the precise composition is unknown.	28532454
Inflammation, Venous Insufficiency	Altered Intercellular Communication	The physiopathology could be related to chronic inflammation associated with venous insufficiency and with certain trigger factors.	28532589
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Low-grade inflammation, endothelial dysfunction, and platelet hyper-reactivity to agonists are associated with an increased risk of cardiovascular events.	28533260
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Neutrophil-lymphocyte ratio (NLR) is a measure of systemic inflammation that appears prognostic in localized and advanced non-small cell lung cancer (NSCLC).	28533476
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Increased systemic inflammation portends a poorer prognosis in cancer patients.	28533476
Inflammation, Acute and chronic inflammation	Altered Intercellular Communication	Normalization of acid reflux in both groups was associated with reduction in papillary length, basal cell layer thickness, intercellular space dilatation, and acute and chronic inflammation of squamous epithelium.	28533674
Muscle Cramp, Inflammation, Arteriovenous fistula, Sleeplessness, Pruritus	Altered Intercellular Communication	Insomnia, muscular cramps and pruritus have low intensity in hemodialysis patients with good dialysis efficiency, low inflammation and arteriovenous fistula.	28534129
Muscle Cramp, Sleeplessness, Inflammation	Altered Intercellular Communication	Insomnia is associated with muscular cramps and inflammation.	28534129
Granulomatous inflammation, Tuberculosis	Altered Intercellular Communication	Cytologic diagnoses rendered were tubercular epididymo-orchitis in 15, granulomatous inflammation suggestive of tuberculosis in six and granulomatous inflammation in 19.	28534708
Inflammation, Labor (Childbirth)	Altered Intercellular Communication	Cell-free DNA, inflammation, and the initiation of spontaneous term labor.	28536048
Degenerative polyarthritis, Inflammation, Osteoarthritis, Knee	Altered Intercellular Communication	Dietary fibre reduces body weight and inflammation both of which are linked with knee osteoarthritis (OA).	28536116
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Together these data show that EVs from stroke patients are proinflammatory in nature and are capable of inducing inflammation in immune cells.	28536169
ARCN1 gene, Bronchitis	Altered Intercellular Communication	Bronchial inflammation and bacterial load in stable COPD is associated with TLR4 overexpression.	28536249
ARCN1 gene, Pseudomonas aeruginosa, Bronchitis	Altered Intercellular Communication	Bacterial load did not correlate with inflammatory cells.Bronchial epithelial overexpression of TLR4 and NOD1 in severe/very severe stable COPD, associated with increased bronchial inflammation and P. aeruginosa bacterial load, may play a role in the pathogenesis of COPD.	28536249
Inflammation, Psoriasis, Thrombophilia	Altered Intercellular Communication	Systemic inflammation and hypercoagulability in psoriasis are related to cardiovascular morbidity.	28536717
Paraparesis, Spastic, Myelitis, Thrombospondin 1, Tropical Spastic Paraparesis, altretamine/doxorubicin/melphalan protocol	Altered Intercellular Communication	A small number of those infected develop the progressive neurodegenerative disease HTLV-1-associated myelopathy (HAM), also known as tropical spastic paraparesis (TSP), which is characterized by chronic spinal cord inflammation and accompanying myelopathic symptoms.	28536850
Pain Distress Question, Inflammation, Dysesthesia, Hypotension, CTCAE, Swelling	Altered Intercellular Communication	Post-procedure adverse events included pain (4.0%), swelling and inflammation (2.7%), dysaesthesia (0.7%) and hypotension (0.7%).	28537343
Inflammation, Hypertensive (finding), Hypertension, CTCAE, Nutritional status	Altered Intercellular Communication	Leukocyte-derived H2S production varied according to the nutritional status of hypertensive subjects, and the H2S/IL-10 signaling pathway may be the junction point among hypertension, disturbance of nutritional status, and inflammation.	28537431
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	C-reactive protein (CRP) is a marker of inflammation that has been shown to be predictive of cardiovascular diseases in adults.	28537577
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	The association of CRP with metabolic syndrome and its components suggests that inflammation may be useful in assessing cardiovascular risk in adolescents.	28537577
Pneumonitis	Altered Intercellular Communication	The degree of lung inflammation was observed; the ratio of the thickness of the wall to the external diameter of the pulmonary arterioles (WT%), and the ratio of the area of the wall to that of the pulmonary arterioles (WA%) were calculated.	28537664
Inflammation	Altered Intercellular Communication	Multivariate regression analysis showed that, compared with the smoking index and inflammation score, TLR4 and MMP-9 expression were the strongest factors affecting the parameters of lung revascularization (WA% and WT%) (p<0.05).	28537664
Hypertrophy, Inflammation, Neoplasms	Altered Intercellular Communication	MRI of the head and orbit revealed bilateral tubular cystic enlargement of the optic nerve/optic sheath complex with thickening of the optic nerves without inflammation or neoplasm, suggestive of bilateral optic nerve meningocele.	28538611
vascular inflammations, AAVS1 gene, Vasculitis, CTCAE	Altered Intercellular Communication	Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is systemic vascular inflammation.	28539536
Inflammation, Psoriasis	Altered Intercellular Communication	Psoriasis is a T helper 1 cell-mediated chronic inflammation.	28540870
Inflammation, Sarcopenia	Altered Intercellular Communication	weak grip strength (GS) and chronic inflammation have been implicated in the aetiology of sarcopenia in older adults.	28541423
Inflammation, Dysbiosis	Altered Intercellular Communication	ART-treated subjects concurrently exhibit marked compositional alterations in the gut bacterial microbiota and the degree of dysbiosis correlates with systemic inflammation.	28541799
Inflammation, Hemorrhage	Altered Intercellular Communication	They presented with severe local inflammation; thus, it was difficult to stop bleeding from the gallbladder bed.	28541859
Inflammation, Hemorrhage	Altered Intercellular Communication	However, in case of severe local inflammation, there is a greater risk for massive hemorrhage.	28541859
HD Term Type, Inflammation, Hypoalbuminemia	Altered Intercellular Communication	In the event of oxidative stress and inflammation to which HD patients are exposed, albumin is oxidized and undetected by common laboratory methods, rendering an apparent hypoalbuminemia.	28542419
Inflammation, Blood Vessel	Altered Intercellular Communication	We wanted to show that these circulating modified oxidized albumin molecules cause direct vascular damage, mediating inflammation.	28542419
Adenoma	Altered Intercellular Communication	EGCs with pre-existing adenoma show a greater association with H. pylori-related chronic inflammation than those without, which could explain the differences in the characteristics between groups.	28542582
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Systemic inflammation is associated with reduced quality of life and increased symptoms in patients with advanced cancer.	28542626
Inflammation, Cardiomyopathies	Altered Intercellular Communication	Immune cells participate in cardiomyopathy development either by direct tissue destruction, or by driving inflammation.	28543170
Inflammation	Altered Intercellular Communication	It has been shown that inflammation may play an important role in the pathophysiology of CI-AKI.	28543803
Inflammation	Altered Intercellular Communication	Studies have implicated that TLR5 is associated with various diseases such as autoimmune and inflammation related diseases.	28543911
Inflammation, Hypertensive (finding), Vascular System Injuries	Altered Intercellular Communication	Kallistatin, an endogenous protein, protects against vascular injury by inhibiting oxidative stress and inflammation in hypertensive rats and enhancing the mobility and function of endothelial progenitor cells (EPCs).	28544111
Steatohepatitis, Inflammation	Altered Intercellular Communication	Novel PPARa agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging.	28545035
Steatohepatitis, Dyslipidemias, Metabolic Syndrome X, Inflammation	Altered Intercellular Communication	Because hepatic steatosis is closely associated with metabolic syndromes, including insulin resistance, dyslipidemia, and inflammation, numerous efforts have been made to develop compounds that ameliorate it.	28545035
Steatohepatitis, Inflammation	Altered Intercellular Communication	In conclusion, MHY553 is a novel PPARa agonist that improved aged-induced hepatic steatosis, in part by increasing b-oxidation signaling and decreasing inflammation in the liver.	28545035
Degenerative polyarthritis, Inflammation, Cartilage damage, glycation	Altered Intercellular Communication	The accumulation of inflammation and cartilage damage induced by advanced glycation end products (AGEs) are important hallmarks of osteoarthritis (OA).	28545202
Inflammation, Atherosclerosis	Altered Intercellular Communication	Moreover, post-translational modifications such as citrullination and carbamylation have been linked to inflammation and atherosclerosis.	28545441
Inflammation, Hypoxia	Altered Intercellular Communication	The expression of membrane bound (mb) Tie2 and Ang-1 ensures vessel stability, whereas Ang-2, inducible by vascular endothelial growth factor (VEGF), hypoxia, and inflammation, acts as an antagonist.	28545512
Sample Size Calculation, Hypoxia	Altered Intercellular Communication	The VEGF tg mouse model, the hypoxia, and the inflammation-dependent bleomycin model all showed a similar dysregulation of Ang/Tie2 as in SSc, which did not apply for the non-inflammatory TSK1 model.	28545512
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Evidence suggests an association between inflammation and depression, although findings are mixed.	28546059
Inflammation, Depression, CTCAE, Cognitive	Altered Intercellular Communication	Negative cognitive bias is a key component of depression, but has not been examined in relation to inflammation.	28546059
Inflammation, Depression, CTCAE	Altered Intercellular Communication	While cross-sectional, results are consistent with research showing that inflammation heightens the salience of negative emotional stimuli, and identify a novel pathway through which inflammation may lead to depression.	28546059
Exanthema, Arthralgia, Quotidian, Autistic behavior, Juvenile-Onset Still Disease, Myalgia, CTCAE 5	Altered Intercellular Communication	BACKGROUND Adult Still's disease (ASD) is a rare systemic inflammatory condition, which commonly presents with the triad of quotidian fevers, rash, and non-specific rheumatologic symptoms such as myalgia and arthralgia.	28546530
Autistic behavior	Altered Intercellular Communication	CONCLUSIONS ASD is a rare systemic inflammatory condition and its nonspecific presentation often leads to diagnostic delay and disease complications.	28546530
Airway structure, Inflammation, Bronchiectasis	Altered Intercellular Communication	Bronchiectasis is characterized by permanent dilatation of the bronchial tree caused by recurrent airway infection and inflammation.	28546745
Inflammation, Atherosclerosis	Altered Intercellular Communication	The association of atherosclerosis and inflammation is well established.	28546745
Inflammation, Uveomeningoencephalitic Syndrome	Altered Intercellular Communication	Early diagnosis and treatment of inflammation are crucial factors in the clinical outcome of Vogt-Koyanagi-Harada disease.	28548582
Periodontal Diseases, prostatitis	Altered Intercellular Communication	The causal effect of periodontal disease on prostatic inflammation has not been established.	28548883
Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	Chronic prostatitis (CPr) and benign prostatic hyperplasia (BPH) are complex inflammatory conditions for which etiologic determinants are still poorly defined.	28548883
Nasopharyngeal carcinoma, Acute and chronic inflammation, Malignant Neoplasms	Altered Intercellular Communication	Chronic sinonasal tract inflammation as a precursor to nasopharyngeal carcinoma and sinonasal malignancy in the United States.	28549211
Inflammation	Altered Intercellular Communication	Impaired monocyte function in MG and decreased expression of genes associated with inflammation resolution could contribute to the chronicity of the disease.	28549776
Muscle damage, Inflammation, Overweight	Altered Intercellular Communication	Muscle damage derived from overweight displayed by oxidative and endoplasmic reticulum (ER) stress induces inflammation and insulin resistance and forces the muscle to increase requirements from autophagy mechanisms.	28549989
Inflammation, Neoplasm Metastasis, Trauma, Nervous System	Altered Intercellular Communication	CD44 is an inflammation-related gene encoding a widely-distributed family of alternatively spliced cell surface glycoproteins that have been implicated in inflammation, metastases, and inflammation-linked neuronal injuries.	28550248
Liver Dysfunction, Overweight, Metabolic Syndrome X	Altered Intercellular Communication	Serum level of chemerin may serve as a measure of ongoing obesity-related inflammation, early marker of subclinical liver dysfunction and metabolic syndrome in overweight pediatric patients.	28551507
Pituitary Gland, Neoplasms	Altered Intercellular Communication	However, due to concerns of side-effects (radiation-associated tumour, relapse outside the radiation field, mental and pituitary hormonal dysfunction), and after discussing both approaches carefully with the patient, the decision was made to treat his pituitary germinoma with chemotherapy alone.	28551652
Airway structure, Carcinoma of lung	Altered Intercellular Communication	Acidification of exhaled breath condensate (EBC), reflecting airway inflammation and oxidative stress, has been reported in lung cancer patients undergoing lobectomy.	28551684
Gastrointestinal inflammation, Colitis	Altered Intercellular Communication	In analyses of intestinal tissues, colitis induction, and gut microbiota in mice with intestinal epithelial disruption of SIRT1, we found this protein to prevent intestinal inflammation by regulating the gut microbiota.	28552621
Inflammation, Hypertension, CTCAE, atherosclerotic	Altered Intercellular Communication	HIV damages vessel endothelium through chronic inflammation, which, combined with dys-lipidaemia, arterial hypertension, and antiretroviral therapy leads to the progression of atherosclerotic changes.	28553846
Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Fatty degeneration	Altered Intercellular Communication	Of the 143 patients with lean NAFLD, 27 had grade 3 steatosis, 24 had a lobular inflammation score greater than 2, 10 had a ballooning score of 2, and 25 had a fibrosis score of 2 or higher.	28554682
Vasculitis, Transplant glomerulopathy	Altered Intercellular Communication	One hundred fifty-four patients with HLA-DSA-associated severe IF/TA showed significantly increased microvascular inflammation, transplant glomerulopathy, C4d deposition in capillaries, and decreased allograft survival compared to 344 patients with severe IF/TA without HLA-DSAs.	28554738
Single organ dysfunction, Inflammation, Infections, Hospital, Kidney Failure	Altered Intercellular Communication	Secondary outcomes include main complications of AP (eg, organ failure and mortality, among others), levels of biological markers of systemic inflammation, epithelial lung injury, renal failure, and healthcare-associated costs.	28554928
Arterial Stiffness, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	It may also cause increased inflammation and fibrosis in the arterial system resulting in an increase in arterial stiffness.	28554985
Multiple Chronic Conditions, Inflammation, Obesity	Altered Intercellular Communication	Obesity has been related to an increased risk of multiple diseases in which oxidative stress and inflammation play a role.	28555008
Inflammation, Obesity	Altered Intercellular Communication	Our aim was to analyze the interrelationship among obesity, diet, oxidative stress, inflammation and the intestinal microbiota in 68 healthy adults (29.4% normal-weight).	28555008
Inflammation, Hyperglycemia, physiopathological	Altered Intercellular Communication	The inflammation and oxidative stress of bone marrow-derived proangiogenic cells (PACs), also named endothelial progenitor cells, triggered by hyperglycemia contributes significantly to vascular dysfunction.	28555162
Inflammation, Osage language, Hypertensive disease, Sleep Apnea, Obstructive, Hypertension, CTCAE	Altered Intercellular Communication	Obesity-associated systemic hypertension (HTN) and obstructive sleep apnea (OSA) have multiple pathophysiological pathways including ectopic fat deposition, inflammation, altered adipokine profile, and increased sympathetic nervous activity.	28555408
Communicable Diseases, Inflammation	Altered Intercellular Communication	The aim of this study was to determine the accuracy of LS combined with bone marrow scintigraphy (BMS), as well as inflammation markers CRP and WBC, in detecting infection in patients with prosthetic joints.	28555449
Inflammation, Juvenile polyposis syndrome	Altered Intercellular Communication	In contrast, however, inflammation markers CRP and WBC are not accurate pre-diagnostic markers for PJI.	28555449
Bronchial brand of guaifenesin-theophylline, Bronchiectasis, Exacerbation, Chronic Obstructive Airway Disease, Bronchitis, Lung diseases	Altered Intercellular Communication	Bronchiectasis is an incurable pulmonary disorder that is characterized pathologically by permanent bronchial dilatation and severe bronchial inflammation and clinically by chronic productive cough and recurrent infectious exacerbations; bronchiectasis often occurs in the presence of chronic obstructive pulmonary disease.	28555504
Inflammation, Cholesteatoma, Otosclerosis, Chronic otitis	Altered Intercellular Communication	A statistically significant difference in inflammation score between otosclerosis and chronic otitis samples ( P < 0.01; Anova test) and between otosclerosis and cholesteatoma samples ( P < 0.05; Anova test) was observed; the HMGB1 positivity was in accordance with the density of the inflammatory infiltrate.	28555513
Inflammation	Altered Intercellular Communication	Although colouterine fistula is usually treated with open surgery, patients with controlled and well-localized inflammation may be good candidates for a laparoscopic approach.	28557372
Inflammation, Diabetic Retinopathy	Altered Intercellular Communication	Inflammation is known to be involved in the progression of diabetic retinopathy.	28558009
prostatitis	Altered Intercellular Communication	Inhibition of chronic prostate inflammation by hyaluronic acid through an immortalized human prostate stromal cell line model.	28558037
prostatitis	Altered Intercellular Communication	These findings suggest that ihPSC could provide a mechanism-based platform for investigating prostate inflammation.	28558037
ARCN1 gene, Communicable Diseases, Chronic Obstructive Airway Disease, Inflammation	Altered Intercellular Communication	Helicobacter pylori (HP) infection is associated with reduced lung function and systemic inflammation in chronic obstructive pulmonary disease (COPD) patients.	28558695
palladium, Chronic Kidney Diseases	Altered Intercellular Communication	A malnutrition-inflammation score (MIS) >= 6 occurred in 37 % of PD patients and in 2.5 % of CKD patients.	28558794
palladium	Altered Intercellular Communication	Apart from age, a condition of malnutrition-inflammation was the major determinant of poor physical activity and capacity in PD patients.	28558794
Cyst, Hematoma, Neoplasms, Necrosis	Altered Intercellular Communication	These may include inflammations, benign tumors, cysts, hematomas, or, more rarely, focal necrosis.	28558811
Inflammation, Hypercholesterolemia, Low-Density Lipoproteins, Endometriosis, Hypertension, CTCAE	Altered Intercellular Communication	Conversely, elevated low-density lipoprotein in hypercholesterolemia and chronic systemic inflammation resulting from hypertension may increase the risk of endometriosis.	28559401
Hypercholesterolemia, Hypertension, CTCAE, Endometriosis	Altered Intercellular Communication	An altered hormonal or chronic systemic inflammatory milieu characterizing endometriosis may result in a higher risk of hypercholesterolemia and hypertension.	28559401
Aneurysm, Inflammation	Altered Intercellular Communication	In the light of recent reports of the association of wall enhancement with unstable aneurysms, we considered wall enhancement to be a marker of inflammation and remodeling of the aneurysm wall, resulting in chronic hemorrhagic suffusion in the subarachnoid spaces.	28559509
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Studies on the etiology of essential hypertension (EH) have demonstrated that chronic inflammation contributes to the onset and development of elevated blood pressure.	28560381
Inflammation	Altered Intercellular Communication	Toll-like receptors (TLRs), important immune receptors, serve a role in chronic inflammation and are associated with EH.	28560381
Inflammation, Trauma, Nervous System, Edema, Neuronal loss in central nervous system, Chronic inflammatory disorder	Altered Intercellular Communication	Connexin43 hemichannels have been called "pathological pores" based upon their role in secondary lesion spread, edema, inflammation, and neuronal loss following central nervous system injuries, as well as in chronic inflammatory disease.	28560708
Tumor necrosis, Inflammation	Altered Intercellular Communication	Tumour necrosis factor alpha (TNF-a), inducible nitric oxide synthase (iNOS), and cyclooxygenase 2 (COX-2) protein expression indicated that EGCG inhibited ACR-induced inflammation.	28561817
Corneal Ulcer, Corneal Neovascularization, Corneal edema, Inflammatory abnormality of the eye	Altered Intercellular Communication	Despite temporary discontinuation of erlotinib treatment, the corneal ulcer continued to worsen with peripheral corneal neovascularization, stromal thinning, corneal edema, and profuse inflammation of the ocular surface.	28562552
Inflammation, Colorectal Carcinoma, Neoplasms	Altered Intercellular Communication	The relationship between tumour stage, systemic inflammation, body composition and survival in patients with colorectal cancer.	28566220
Peripheral Vascular Diseases, Inflammation	Altered Intercellular Communication	Periodontitis deteriorates peripheral arterial disease in Japanese population via enhanced systemic inflammation.	28567552
Inflammation, Tooth number	Altered Intercellular Communication	In conclusion, we clarified that PAD patients had decreased tooth number and worsened oral and periodontal condition with enhanced systemic inflammation.	28567552
Inflammation, Actual blood loss	Altered Intercellular Communication	The 5-dose TXA regimen can further reduce the blood loss, diminish the maximum Hb drop, minimize inflammation, enhance mobility, and shorten LOS following TKA, without increasing the risk of complications.	28567578
Blood Clot, Endocarditis	Altered Intercellular Communication	Valve inflammation and thrombus formation was mild in majority of the cases.	28569053
Refractory anemias, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Lipid profiles appear to be altered in rheumatoid arthritis (RA) patients because of disease activity and inflammation.	28569219
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Histopathology demonstrated chronic inflammation in the setting of hyalinized fibrosis (7/7).	28570415
Pain Distress Question, Inflammation, Fatigue	Altered Intercellular Communication	In those reporting severe fatigue (Short-Form 36 vitality <= 12.5), this cross-sectional analysis applied hierarchical clustering with weighted-average linkage identified clusters of pain, fatigue, mental health (all Short-Form 36), disability (Health Assessment Questionnaire), and inflammation (erythrocyte sedimentation rate) in the DMARD cohort.	28570437
Disability, Inflammation, Pain Distress Question	Altered Intercellular Communication	All clusters had severe levels of pain and disability and were distinguished by the presence/absence of poor mental health and high inflammation.	28570437
Cerebrovascular Disorders	Altered Intercellular Communication	These results agree with previous observations of the chronic inflammation/prothrombotic tendency in patients with cerebrovascular disease.	28570705
Orbital Pseudotumor	Altered Intercellular Communication	Consensus on Diagnostic Criteria of Idiopathic Orbital Inflammation Using a Modified Delphi Approach.	28570731
Primary malignant neoplasm, Orbital Pseudotumor	Altered Intercellular Communication	Current practice to diagnose idiopathic orbital inflammation (IOI) is inconsistent, leading to frequent misdiagnosis of other orbital entities, including cancer.	28570731
Orbital Pseudotumor	Altered Intercellular Communication	By specifying criteria, diagnosis of orbital inflammation will be improved.	28570731
Inflammation, Dacryoadenitis, Orbital Pseudotumor, Orbital Myositis	Altered Intercellular Communication	The items were clustered around the anatomic subtypes of IOI: idiopathic dacryoadenitis and idiopathic orbital fat inflammation (2 nonmyositic IOIs), and idiopathic orbital myositis (myositic IOI).	28570731
Gastroesophageal reflux disease, Inflammation	Altered Intercellular Communication	Given that OAC stems from acid reflux and that the oesophageal epithelium undergoes a metaplasia-dysplasia transition from the resulting inflammation, it is plausible that a high DII score (indicating a pro-inflammatory diet) may exacerbate risk of OAC and its precursor conditions.	28571591
Esophageal carcinoma	Altered Intercellular Communication	In conclusion, a pro-inflammatory diet may exacerbate the risk of the inflammation-metaplasia-adenocarcinoma pathway in oesophageal carcinogenesis.	28571591
Constriction procedure, Myocarditis	Altered Intercellular Communication	Cardiac magnetic resonance imaging confirmed a globally thickened pericardium and showed evidence of pericardial inflammation and constrictive physiology.	28572226
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Recent studies suggest the role of inflammation in the pathogenesis of OA.	28573383
Inflammation, Degenerative disorder of cartilage	Altered Intercellular Communication	The knee joint experiences more mechanical stress, cartilage degeneration, and inflammation than the hip joint.	28573383
Inflammation	Altered Intercellular Communication	This facilitates increased cartilage degradation and inflammation in the joint.	28573383
Inflammation, melanoma	Altered Intercellular Communication	Nucleated cells in the dermis and the RCM correlate of dermal inflammation were also significant RCM features favouring DM over MIS, as well as invasive melanoma over MIS.	28573666
Tears body substance, Inflammation, Macular Edema, Cystoid	Altered Intercellular Communication	Main complications observed were prolonged postoperative inflammation in 25% (n = 31), posterior capsular tears in 0.45% (n = 11), and unilateral cystoid macular edema in 0.08% (n = 2) eyes.	28573990
Cataract, Inflammation	Altered Intercellular Communication	After inflammation control, complicated cataract was managed surgically under perioperative steroid cover.	28574002
Inflammation, Acquired Immunodeficiency Syndrome, Uveomeningoencephalitic Syndrome	Altered Intercellular Communication	This case shows that significant inflammation can be seen even in HIV/AIDS patients on HAART with VKH in spite of moderate CD4 counts.	28574002
Inflammation, cardiac muscle tissue growth	Altered Intercellular Communication	mRNA transcripts involved in activation of satellite cells, myogenesis, regeneration, adipogenesis, muscle growth and tissue inflammation were assessed.	28574407
Inflammation, melanoma	Altered Intercellular Communication	Growing evidence indicates that inflammation plays a critical role in the development and progression of acral melanoma.	28574975
Tumor necrosis, Primary malignant neoplasm, Inflammation	Altered Intercellular Communication	Tumor necrosis factor-a (TNF-a), an important factor in systematic inflammation, is reportedly involved in several cancer types.	28575042
Inflammation, Obesity	Altered Intercellular Communication	Impacts of chronic systemic inflammation and body size and their interaction effect on insulin resistance in Asian populations, in whom obesity is less common, are not fully understood.	28575103
Inflammation, Obesity	Altered Intercellular Communication	Concomitant obesity and elevated systemic inflammation may synergistically contribute to increased insulin resistance.	28575103
Inflammation, Impaired cognition, "Alzheimers Disease	Altered Intercellular Communication	Brain inflammation accompanies amyloid in the majority of mild cognitive impairment cases due to Alzheimer's disease.	28575151
Inflammation, Impaired cognition	Altered Intercellular Communication	11C-(R)-PK11195 positron emission tomography reveals increased inflammation in a majority of amyloid positive mild cognitive impairment cases, its cortical distribution overlapping that of amyloid deposition.	28575151
Granuloma, Inflammation, Caseous necrosis	Altered Intercellular Communication	Tissue acquisition revealed epithelioid granuloma in 33 patients, caseous necrosis in 13, a positive AFB stain in 14, and nonspecific chronic inflammation in 2.	28575247
Inflammation	Altered Intercellular Communication	The remaining two with only nonspecific chronic inflammation received empirical antitubercular chemotherapy based solely on EUS morphology.	28575247
Inflammation, Endophthalmitis, CTCAE	Altered Intercellular Communication	Exogenous endophthalmitis is an ophthalmologic emergency defined by panocular inflammation.	28576209
Inflammation	Altered Intercellular Communication	Vascular endothelial growth factor A (VEGF-A) contributes to inflammation by promoting chemotaxis of monocytes and granulocytes and by increasing vascular permeability.	28576209
Malignant tumor of colon, Dysbiosis	Altered Intercellular Communication	Thus, pig model can aid in the development of preventive strategies against gut bacterial dysbiosis and inflammation-promoted diseases, such as colon cancer.	28576788
Inflammation, Mycobacterium Infections	Altered Intercellular Communication	He underwent renal biopsy that revealed necrotizing granulomatous inflammation suggestive of mycobacterial infection.	28577928
Fracture	Altered Intercellular Communication	Endogenous parathyroid hormone (PTH) plays an important role in fracture healing.	28578352
Malignant neoplasm of urinary bladder	Altered Intercellular Communication	To explore the prognostic significance of preoperative prognostic nutritional index (PNI) in bladder cancer after radical cystectomy and compare the prognostic ability of inflammation-based indices.	28578683
Inflammation, Fibrosis Assessment, Hepatitis C	Altered Intercellular Communication	Interferon-gamma (IFN-g)-inducible protein-10 (IP-10), soluble (s) CD163 and sCD14 play an important role in the pathogenesis of HCV and HIV infection and are involved in inflammation and liver fibrosis.	28578937
Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Association of Systemic Inflammation Score With Atrial Fibrillation: A Case-Control Study With Propensity Score Matching.	28579228
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Inflammation plays a key role in the initiation and progression of atrial fibrillation (AF).	28579228
Inflammation, Pythiosis, Destruction (action)	Altered Intercellular Communication	Corneal pythiosis showed epithelial ulceration, stromal destruction, and varying inflammation; load and distribution of Pythium were inversely proportional to inflammation.	28582375
Inflammation, Diabetic peripheral neuropathy, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Diabetic peripheral neuropathy (DPN) had been demonstrated as a chronic inflammation state and one of the most common complications of type 2 diabetes mellitus (T2DM).	28582723
Inflammatory disorder, Diabetes Mellitus	Altered Intercellular Communication	Neutrophil-to-lymphocyte ratio (NLR) is a novel marker to reflect many kinds of chronic inflammation disease including diabetes.	28582723
Inflammation, Dementia	Altered Intercellular Communication	Alterations in the immune response that result in inflammation might play a role in the pathology of dementias.	28582858
Inflammation	Altered Intercellular Communication	The inflammation was successfully resolved, and the implant was removed through a minimally invasive endoscopic sinus surgery technique.	28582957
Inflammation, Primary malignant neoplasm, Colorectal Carcinoma	Altered Intercellular Communication	Inflammation is widely recognized to play an important role in cancer progression, and the peripheral monocyte count has been reported to correlate with the prognosis in patients with colorectal cancer.	28583114
Atrophy of prostate, Inflammation, Prostate carcinoma	Altered Intercellular Communication	The combination of histological prostate atrophy and inflammation is associated with lower risk of prostate cancer in biopsy specimens.	28585572
Atrophy of prostate, Prostate carcinoma, prostatitis, Structure of posterior cerebral artery	Altered Intercellular Communication	To evaluate whether the presence of both prostate atrophy (PA) and chronic prostate inflammation (CPI) in the same biopsy and in the same biopsy core are associated with prostate cancer (PCa) risk and grade in repeat biopsies.	28585572
Gastrointestinal inflammation	Altered Intercellular Communication	These data suggest that IL-17A+ IFN-g+ and IL-22+ IFN-g+ T cell subsets might represent the pathogenic T helper type 17 (Th17) population in the context of intestinal inflammation for CD patients.	28586085
Crohn Disease	Altered Intercellular Communication	Crohn's disease (CD) is a chronic inflammatory condition of the human gastrointestinal tract whose aetiology remains largely unknown.	28586085
Inflammation, Hypertensive (finding), metabolic disturbance	Altered Intercellular Communication	Salsalate ameliorates metabolic disturbances by reducing inflammation in spontaneously hypertensive rats expressing human C-reactive protein and by activating brown adipose tissue in nontransgenic controls.	28586387
Inflammation	Altered Intercellular Communication	Chronic low-grade inflammation plays an important role in the pathogenesis of insulin resistance.	28586387
Dermatitis, Necrotizing fasciitis	Altered Intercellular Communication	Necrotizing fasciitis (NF) is a serious and potentially fatal condition where there is rapid progression of inflammation of skin, subcutaneous tissue, and superficial fascia and can be mono-microbial or poly-microbial.	28586594
Inflammation, Chronic multifocal osteomyelitis	Altered Intercellular Communication	Histopathology demonstrated only non-specific chronic inflammation compatible with CRMO.	28587611
Inflammation	Altered Intercellular Communication	Furthermore, inflammation plays an important role in the pathogenesis of BC.	28587816
Inflammation, Obesity	Altered Intercellular Communication	Obesity is associated with chronic, low grade, systemic inflammation.	28588155
Inflammation, Fibrosis Assessment, Asbestosis	Altered Intercellular Communication	We studied if YKL-40 is related to inflammation, fibrosis, and/or lung function in subjects exposed to asbestosis.	28588347
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The present finding suggests YKL-40 as a biomarker associated with fibrosis and inflammation in asbestos-exposed subjects.	28588347
Inflammation	Altered Intercellular Communication	These findings suggest that higher SFA and minor n-6 HUFA, namely PA and AA, are associated with increased low-grade inflammation in children, whereas the major dietary n-6 PUFA and total PUFA are associated with reduced inflammation.	28589948
Inflammation	Altered Intercellular Communication	Elevated desaturase activity, estimated by the ratio AA/LA, may be associated with higher inflammation, particularly in boys.	28589948
Peripheral retinoschisis, Peripheral Ischemia, Vitreous inflammatory cells, Uveitis	Altered Intercellular Communication	The appearance of peripheral retinoschisis in this series of uncontrolled intermediate uveitis patients seems to be secondary to a complex balance between the persistent fluorescein leakage, a subclinical peripheral ischemia, and the constant low-grade vitreous inflammation that causes vitreous shrinkage and traction.	28590967
Inflammation	Altered Intercellular Communication	Good preoperative and postoperative control of inflammation plays an important role in achieving favorable visual outcomes.	28591283
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	In conclusion, elevated WBC count served as a predictor of the odds of kidney function decline in this population, which supports the hypothesis that systemic inflammation may serve as a risk factor for CKD development.	28592280
Toxic effect, Hypokalemia, Asthenia, DLST wt Allele, Dermatitis acneiform	Altered Intercellular Communication	Dose-limiting toxicities (DLTs) included grade 4 hypokalemia and grade 3 mucosal inflammation, asthenia, and dermatitis acneiform.	28592615
Inflammation, Native Valve Endocarditis, Heart failure	Altered Intercellular Communication	Patients with a perivalvular abscess had a greater number ofStaphylococcusspecies and prosthetic valve endocarditis, a greater level of inflammation at diagnosis and symptomatic heart failure before surgery, especially in the ARR group.	28592753
Inflammation, Cystitis, Pneumonia, Leukemia, Myelomonocytic, Chronic, Inflammatory disorder of cartilage	Altered Intercellular Communication	Here, we describe the occurrence of eosinophil-rich tissue inflammation, including eosinophilic pneumonia, chondritis, and cystitis, in CMML patients.	28593791
hearing impairment, Inflammation, Ear Inflammation	Altered Intercellular Communication	Association of Gel-Forming Mucins and Aquaporin Gene Expression With Hearing Loss, Effusion Viscosity, and Inflammation in Otitis Media With Effusion.	28594978
hearing impairment, Inflammation, Otitis Media with Effusion	Altered Intercellular Communication	To investigate the association of gel-forming mucins and aquaporin 5 (AQP5) gene expression with inflammation, effusion viscosity, and hearing loss in pediatric OM with effusion (OME).	28594978
Inflammation	Altered Intercellular Communication	Recent evidence indicates that a systemic state of inflammation may impair fertility, but data about psoriatic males are scarce.	28595175
Inflammation, Psoriasis	Altered Intercellular Communication	Ultrasound signs of inflammation of the accessory glands were observed in 35/50 patients with psoriasis and in none of the controls.	28595175
Inflammation	Altered Intercellular Communication	We also found that this might be due to an impact of systemic inflammation on the hormonal profile and on sexual accessory gland inflammation.	28595175
Inflammation	Altered Intercellular Communication	We also found that this might be due to an impact of systemic inflammation on the hormonal profile and on sexual accessory gland inflammation.	28595175
Parkinson Disease, Inflammation	Altered Intercellular Communication	White matter damage and systemic inflammation in Parkinson's disease.	28595572
Parkinson Disease, Inflammation, palladium, Leukoaraiosis	Altered Intercellular Communication	Systemic inflammation and white matter (WM) alterations have been noted as effects of Parkinson's disease (PD).	28595572
palladium, Inflammation	Altered Intercellular Communication	Patients with PD experience WM integrity damage in vulnerable regions, and these impairments are associated with increased disease severity and systemic inflammation.	28595572
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Non-alcoholic Fatty Liver Disease, Liver damage	Altered Intercellular Communication	Low-grade inflammation, oxidative stress and ectopic fat, common features of chronic obstructive pulmonary disease (COPD), might contribute to the development of NAFLD.We aimed to investigate the prevalence of NAFLD and to evaluate the relationship between various types of liver damage and COPD severity, comorbidities and circulating inflammatory cytokines.	28596431
Moyamoya Disease, MMD gene	Altered Intercellular Communication	Immuno-inflammation has been shown to play a pivotal role in the pathogenesis of moyamoya disease (MMD).	28596558
Inflammation	Altered Intercellular Communication	The pathological diagnosis showed only chronic inflammation in their medical records.	28596692
Inflammation, Fibrosis Assessment, Heart failure	Altered Intercellular Communication	Objective We performed a prospective observational study to explore the prognostic value of plasma galectin-3, a biomarker for fibrosis and inflammation, in Chinese patients with heart failure (HF).	28597803
Aneurysm, Endothelium, Inflammation	Altered Intercellular Communication	These predictors of multiple aneurysms likely reflect a predisposition toward inflammation and endothelial injury.	28598275
Refractory anemias, Rheumatoid Arthritis, Arthritis, Infiltration	Altered Intercellular Communication	Rheumatoid arthritis (RA) is characterized by chronic joint inflammation and infiltration by activated macrophages.	28598681
Communicable Diseases, Inflammation, Pain Distress Question	Altered Intercellular Communication	We evaluated: wound healing time, pain severity and duration, the frequency of dressing change, donor site re-epithelialisation, donor site complications (signs of inflammation or infection).	28598760
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Additionally, 110 (37.2%) had clinically significant (stage 2+) fibrosis and 256 (86.5%) had portal inflammation.	28600116
Inflammation, Fibrosis Assessment, Fatty Liver Disease	Altered Intercellular Communication	CCRL2 mRNA levels were positively correlated with inflammation, fibrosis and NASH scores in the patients.	28600126
Inflammation	Altered Intercellular Communication	These indicated ongoing inflammation, bone formation and increased fibroblasts activity in the FJ bone.	28600230
Inflammatory disorder	Altered Intercellular Communication	Asthma is an inflammatory disease and interleukin 12 (IL-12) may play a regulatory role in allergen-induced inflammation.	28600552
Inflammation	Altered Intercellular Communication	Chronic inflammation in AC might be associated with late onset complications.	28600745
Inflammation, Destruction of tissue	Altered Intercellular Communication	Oxidative stress as a consequence of immune cell activation and disease-modifying anti-rheumatic drugs can prevent inflammation and tissue destruction.	28601049
Colorectal Carcinoma	Altered Intercellular Communication	The cohort consisted of newly diagnosed CRC adult patients during 2003-2010 with at least one prescription of nonsteroidal anti-inflammation drugs.	28601236
Inflammation, Bone necrosis	Altered Intercellular Communication	The effect of chronic dental inflammation on development of Stage 0 medication-related osteonecrosis of the jaw.	28601298
Inflammation	Altered Intercellular Communication	Chronic inflammation may contribute to Stage 0 MRONJ; however, its role may not be sufficient alone for its development.	28601298
Inflammation, Crohn Disease	Altered Intercellular Communication	Correlation between fecal calprotectin and inflammation in the surgical specimen of Crohn's disease.	28601328
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Chiorean's score was used to grade pathologic features (inflammation or fibrosis).	28601328
Inflammation	Altered Intercellular Communication	Among inflammatory markers, only FC was significantly associated with the degree of histologic inflammation in the surgical specimen (P < 0.003).	28601328
Inflammation	Altered Intercellular Communication	Ordinal regression analysis showed the probability of a greater or lesser degree of inflammation based on the value of preoperative FC.	28601328
Inflammation, Intestines, Small	Altered Intercellular Communication	FC is an excellent biomarker of inflammatory activity in small bowel CD as it correlates with histologic inflammation in the surgical specimen.	28601328
Squamous cell carcinoma of esophagus	Altered Intercellular Communication	A novel systemic immune-inflammation index predicts survival and quality of life of patients after curative resection for esophageal squamous cell carcinoma.	28601935
Neoplasms	Altered Intercellular Communication	A novel systemic immune-inflammation index (SII) based on platelet (P), neutrophil (N), and lymphocyte (L) counts has been reported to be associated with clinical outcomes in several solid tumors.	28601935
Intrahepatic Cholangiocarcinoma	Altered Intercellular Communication	Various inflammation-based prognostic biomarkers such as the platelet to lymphocyte ratio and neutrophil to lymphocyte ratio, are related to poor survival in patients with intrahepatic cholangiocarcinoma (ICC).	28602056
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Mdr2-/- mice provide a reliable in vivo model of PSC and develop characteristic biliary inflammation and fibrosis.	28602220
Inflammation, Colon diverticulum anatomic structure	Altered Intercellular Communication	Colonic Diverticula Are Not Associated With Mucosal Inflammation or Chronic Gastrointestinal Symptoms.	28603053
Diverticular disease of colon	Altered Intercellular Communication	Colonic diverticulosis has been reported to be associated with low-grade mucosal inflammation, possibly leading to chronic gastrointestinal symptoms.	28603053
Inflammation, HAMA - Gastrointestinal Symptoms, Diverticulum	Altered Intercellular Communication	We aimed to determine mucosal inflammation and whether diverticula are associated with chronic gastrointestinal symptoms.	28603053
Inflammation, Diverticulum	Altered Intercellular Communication	We explored whether inflammation was present among symptomatic participants with and without diverticula.	28603053
Inflammation, Diverticulosis	Altered Intercellular Communication	There was no evidence for inflammation in patients with symptoms when patients with vs without diverticulosis were compared.	28603053
Diverticular disease of colon, Gastrointestinal symptom, Inflammatory disease of mucous membrane	Altered Intercellular Communication	We found no evidence that colonic diverticulosis is associated with mucosal inflammation or gastrointestinal symptoms.	28603053
Inflammation, Diverticulum	Altered Intercellular Communication	Among patients with symptoms and diverticula, we found no mucosal inflammation.	28603053
Cows milk", Inflammation	Altered Intercellular Communication	After food reintroduction, the most common food triggers that induced histologic inflammation were cow's milk (85%), egg (35%), wheat (33%), and soy (19%).	28603055
Esophagitis, "Extra-osseous Ewings sarcoma	Altered Intercellular Communication	One food trigger that induced recurrence of esophageal inflammation was identified in 62% of patients and cow's milk-induced EoE was present in 88% of these patients.	28603055
Inflammation, Primary malignant neoplasm, Colorectal Carcinoma	Altered Intercellular Communication	STAT3 signaling pathway is regarded as the "bridge" between inflammation and cancer, and involved in the development of CRC.	28603075
Hairy Cell Leukemia, Inflammation	Altered Intercellular Communication	CD11c, expressed not only in Hairy cell leukemia but also in dendritic cells, macrophages and monocytes is a differentiation marker for inflammation.	28603911
Autoimmune Diseases, Inflammation, Chronic Lymphocytic Leukemia, Neoplasms	Altered Intercellular Communication	Prolonged inflammation in the microenvironment of CLL cells may cause a susceptibility to autoimmune disorders and secondary tumors in CLL, in this way, an increase in mortality.	28603911
Inflammation, Arthritis	Altered Intercellular Communication	In the current study, we tested whether the association between well-being and inflammation results in a lower risk of arthritis.	28604559
Osteoporosis	Altered Intercellular Communication	However, the incidence and risk of osteoporosis after acute inflammation of pancreas remained known.	28604838
Inflammation, Nerve injury, Gout	Altered Intercellular Communication	Our clinical case is another example of how gout can produce spinal inflammation and nerve damage and superimpose on previously damaged joints and how patients' compliance to therapeutics may have an important impact on prognosis.	28605749
Inflammation	Altered Intercellular Communication	We conclude that altered levels of OEA and PEA might indicate the presence of systemic inflammation in CWP.	28606089
Pneumonitis	Altered Intercellular Communication	This outperforming of the weighted GRS was confirmed in a real data application on lung inflammation in the SALIA cohort (n = 402).	28606108
Inflammation, Traumatic injury	Altered Intercellular Communication	Heightened local inflammation due to muscle trauma or disease is associated with impaired bone regeneration.	28606129
Inflammatory Bowel Diseases, CDISC Integrated Basic Data Structure Dataset, Gastrointestinal inflammation	Altered Intercellular Communication	An increasing number of physicians use repeated measurements of stool calprotectin to monitor intestinal inflammation in patients with inflammatory bowel diseases (IBDs).	28606846
Inflammation, Cardiovascular Diseases, Refractory anemias, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Rheumatoid Arthritis	Altered Intercellular Communication	Systemic inflammation appears to contribute to the excess risk of cardiovascular disease (CVD) in rheumatoid arthritis (RA).	28606965
Inflammation, CHOP regimen, Arthritis, Psoriatic	Altered Intercellular Communication	The dynamics of response as measured by multiple composite outcome tools in the TIght COntrol of inflammation in early Psoriatic Arthritis (TICOPA) trial.	28606970
Inflammation, neuron death	Altered Intercellular Communication	Targets of these microRNAs include proteins regulating neuronal death, tissue remodelling, gliosis and inflammation.	28607431
Inflammation	Altered Intercellular Communication	Oxidative stress is one of the major causes of inflammation in NAFLD/NASH.	28608557
allergic inflammation, Illness (finding)	Altered Intercellular Communication	Allergic inflammation has been linked to increased susceptibility to viral illnesses, but it is unclear whether this association is causal.	28608756
glycation, Inflammation	Altered Intercellular Communication	Receptor for advanced glycation end products (RAGE) and its cleavage fragment soluble RAGE (sRAGE) are opposite players in inflammation.	28608784
Inflammation, Shock, Cardiogenic	Altered Intercellular Communication	Maintaining MMP-9 activity could be a therapeutic target to limit RAGE-induced deleterious inflammation in cardiogenic shock.	28608784
Malignant - descriptor, Granulomatous inflammation	Altered Intercellular Communication	Among PET-positive LNs, 41.9% were malignant, 41.9% showed reactive changes or granulomatous inflammation, and 9.3% were nondiagnostic by EBUS-TBNA.	28609021
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The 12-lipoxygenase (12-LO) pathway produces proinflammatory metabolites, and its activation is implicated in islet inflammation associated with type 1 and type 2 diabetes (T2D).	28609824
Tumor necrosis, Inflammation	Altered Intercellular Communication	Human islets from nondiabetic donors were incubated with a mixture of tumor necrosis factor a , interluekin-1b, and interferon-g to model islet inflammation.	28609824
Orbital Pseudotumor	Altered Intercellular Communication	Patients observed due to idiopathic inflammation of the mesentery were identified.	28610559
Inflammation, Fever, CTCAE	Altered Intercellular Communication	All four had marked systemic inflammation, fever and fluctuating radiologic findings.	28610559
Idiopathic Inflammatory Myopathies, Retractile Mesenteritis	Altered Intercellular Communication	Sclerosing mesenteritis (SM) is sometimes used as an umbrella-term for idiopathic inflammatory conditions in the mesentery.	28610559
Inflammation	Altered Intercellular Communication	increased production of IL-1b or IL-6), whereas it blunted inflammatory mediators in macrophages and consequently chronic inflammation.	28610607
Inflammation, Dyslipidemias, Diabetes Mellitus, Heart Diseases, Obesity	Altered Intercellular Communication	Close cardiac screening and aggressive modification of other manifestations of AS that are risk factors for cardiac disease, including obesity, inflammation, diabetes and dyslipidemia, are essential in caring for patients with AS.	28610912
Inflammation, Rheumatoid Arthritis, Pain Distress Question	Altered Intercellular Communication	Magnetic resonance imaging assessed inflammation in the wrist is associated with patient-reported physical impairment, global assessment of disease activity and pain in early rheumatoid arthritis: longitudinal results from two randomised controlled trials.	28611080
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To examine whether MRI assessed inflammation and damage in the wrist of patients with early rheumatoid arthritis (RA) are associated with patient-reported outcomes (PROs).	28611080
Inflammation	Altered Intercellular Communication	MRI inflammation, but not damage, showed statistically significant associations with HAQ, VAS-PtGlobal and VAS-pain for status and change scores, independently of C reactive protein and swollen joint count.	28611080
Refractory anemias, Inflammation, Pain Distress Question	Altered Intercellular Communication	MRI-assessed inflammation, but not damage, in early RA wrists is associated with patient-reported physical impairment, global assessment of disease activity and pain and influences the physical function in the hand.	28611080
Inflammation, Fibrosis Assessment, Fatty degeneration	Altered Intercellular Communication	With metformin, weighted liver histologic scores for steatosis, ballooning, and fibrosis did not demonstrate significant improvement and lobular inflammation worsened significantly (weighted mean increase 0.21, 95% CI 0.11 to 0.31, P < 0.0001).	28611274
Inflammation, Fatty degeneration	Altered Intercellular Communication	The liver histology score including steatosis (OR 3.51, 95% CI 2.14 to 5.78) and lobular inflammation (OR 2.65, 95% CI 1.69 to 4.15) improved with TZDs.	28611274
Inflammation, Fatty degeneration	Altered Intercellular Communication	With Vitamin E, weighted liver histologic scores for steatosis (weighted mean decrease -0.60, 95% CI -0.85 to -0.35, P < 0.0001), lobular inflammation (weighted mean decrease - 0.40, 95% CI -0.61 to -0.20, P = 0.0001) and ballooning (weighted mean decrease -0.30, 95% CI -0.54 to -0.07, P = 0.01) demonstrated significant improvement compared to placebo.	28611274
Inflammation, Dental Plaque	Altered Intercellular Communication	Comparative evaluation of Mangifera indica leaf mouthwash with chlorhexidine on plaque accumulation, gingival inflammation, and salivary streptococcal growth.	28611324
Inflammation, Bulla	Altered Intercellular Communication	While cytokines are crucial for the affinity and activation of different leukocyte cells in the inflammation and blister formation, there are no studies concerning a role of IL-36.	28611508
Hidradenitis Suppurativa	Altered Intercellular Communication	Hidradenitis suppurativa is a painful and disfiguring chronic inflammatory condition affecting both men and women.	28612149
Inflammation, Fatty degeneration	Altered Intercellular Communication	In an ordinal logistic regression, significant risk factors for steatosis were female gender (OR 1.5, P = 0.034) and inflammation grade (P = 0.001).	28612194
Adenoma, Basal Cell, Malignant Neoplasms	Altered Intercellular Communication	The analysed material included 27 MA, 26 PA, 1 basal cell adenoma, 8 inflammatory conditions, and 10 malignant neoplasms.	28612315
Inflammation	Altered Intercellular Communication	Further, moderate drinkers had lower CRP levels suggesting that inflammation partially mediates the relationship between moderate alcohol use and depressive symptomatology.	28612359
Waldenstrom Macroglobulinemia, Fibrosis Assessment, Mass in breast	Altered Intercellular Communication	Histologic examination showed fibrosis and dense lymphoplasmacytic inflammation in the breast mass and muscle biopsy.	28612666
Inflammatory Bowel Diseases, Crohn Disease, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In the two inflammatory bowel diseases, ulcerative colitis (UC) and Crohn's disease (CD), altered expression of tight junction (TJ) proteins leads to an impaired epithelial barrier including increased uptake of luminal antigens supporting the inflammation.	28612843
Inflammation, Heart failure	Altered Intercellular Communication	Growth differentiation factor-15 (GDF-15), a biomarker associated with remodeling, oxidative stress and inflammation, has been used to stratify heart failure (HF) patients.	28612904
Coin lesion of lung	Altered Intercellular Communication	It is not known whether IgG4-RD can be diagnosed on the basis of pulmonary lesions only, because increases in serum IgG4 levels and infiltration of IgG4-positive plasma cells into the lung tissue also occur in other inflammatory conditions.	28614225
Inflammation, Abnormality of the vasculature, Chronic Kidney Diseases	Altered Intercellular Communication	IL-33 and ST2 levels in chronic kidney disease: Associations with inflammation, vascular abnormalities, cardiovascular events, and survival.	28614418
Vascular System Injuries, Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Increased inflammation, associated with the increase in chronic kidney disease (CKD) stage, has a very important influence in vascular injury and cardiovascular diseases.	28614418
Communicable Diseases, Cirrhotic, Inflammation, Bacterial Infections	Altered Intercellular Communication	However, there have been no studies of the trends in endocan levels in cirrhotic patients with bacterial infection and their associations with markers of infection and inflammation.	28614777
Communicable Diseases, Inflammation, Liver Cirrhosis	Altered Intercellular Communication	We analyzed the association of endocan with clinical factors in cirrhosis by comparison with indicators of infection and inflammation.	28614777
Communicable Diseases, Malignant Neoplasms, Rheumatism	Altered Intercellular Communication	Infection was the most prevalent cause (55.1%), followed by rheumatologic diseases (7.5%), multiple causes (5.6%), other inflammatory conditions (5.4%), malignancy (5.1%), drug reactions (1.7%), and other conditions (2.0%).	28615410
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Increasing evidence suggests that inflammation plays a central role in driving joint pathology in certain patients with osteoarthritis (OA).	28615667
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Since many patients with OA are obese and increased adiposity is associated with chronic inflammation, we investigated whether obese patients with hip OA exhibited differential pro-inflammatory cytokine signalling and peripheral and local lymphocyte populations, compared to normal weight hip OA patients.	28615667
Airway structure, ARCN1 gene	Altered Intercellular Communication	Systemic and airway inflammation play roles in the pathogenesis of COPD exacerbation.	28615935
Inflammation, Erdheim-Chester Disease, Histiocytosis, Non-Langerhans-Cell, Traumatic injury	Altered Intercellular Communication	Erdheim-Chester Disease (ECD) is a rare type of non-Langerhans cell histiocytosis characterized by tissue inflammation and injury caused by macrophage infiltration and histologic findings of foamy histiocytes.	28617889
Histiocytosis, Non-Langerhans-Cell, Gastrointestinal inflammation	Altered Intercellular Communication	Non-Langerhans histiocytosis and ECD are rare causes of gastrointestinal inflammation.	28617889
Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	We aimed to assess whether the inflammation-related microRNA-155 is associated with the development of adverse left ventricular (LV) remodeling following ST elevation myocardial infarction (STEMI).	28618412
Inflammation, Transcription Initiation	Altered Intercellular Communication	Inflammation is strongly associated with cancer initiation, and the role of LDL in intestinal tumorigenicity should be further explored.	28618417
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Inflammation is a new hallmark feature of cancer initiation and progression.	28618954
Inflammation, Renal Cell Carcinoma Pathway	Altered Intercellular Communication	Time-dependent effects of prognostic biomarkers of systemic inflammation in patients with metastatic renal cell carcinoma.	28618965
Terminal illness, Inflammation	Altered Intercellular Communication	Terminal disease progression with severe systemic inflammation was detected in 87% of the 90 patients who died.	28618965
Inflammation, Humor, Periphlebitis	Altered Intercellular Communication	Anterior inflammation and periphlebitis gradually improved and VZV-DNA in the aqueous humor was reduced to 1.02 x 106 copies/mL at 4 weeks after presentation.	28619012
Inflammation, Humor	Altered Intercellular Communication	Examination by slit lamp microscope revealed no inflammation after 5 months, and VZV-DNA could no longer be detected in the aqueous humor.	28619012
Inflammatory abnormality of the eye	Altered Intercellular Communication	Serum anti-VZV IgG and anti-VZV IgM also showed a gradual decrease along with improvement in ocular inflammation.	28619012
Inflammatory abnormality of the eye, Hyphema, Humor, Uveitis	Altered Intercellular Communication	VZV-associated uveitis may develop hyphema that obscures ocular inflammation, thus PCR analysis using the aqueous humor is the key investigation necessary for the diagnosis.	28619012
Have Autoimmune or Inflammatory Condition	Altered Intercellular Communication	Autoimmune inflammation is common in the early stages of MS and is followed by neurodegenerative processes.	28619424
PROS1 gene, Arthritis	Altered Intercellular Communication	In patients with PsA, poor sleep is associated with active joint inflammation.	28620064
Inflammation	Altered Intercellular Communication	We identified differences in expression of mucin genes, cytokeratin-14 and molecular markers of inflammation.	28620964
Sarcoidosis	Altered Intercellular Communication	Pediatric sarcoidosis comprises a spectrum of childhood granulomatous inflammatory conditions.	28621099
Inflammation	Altered Intercellular Communication	To report a case of severe anterior segment inflammation secondary to exposure to a high-power blue laser device.	28622043
Inflammation, Biliary calculi, Mucous Membrane, Lobular Endocervical Glandular Hyperplasia, Intestinal metaplasia	Altered Intercellular Communication	Despite paucity of inflammation and gallstones, findings attributed to mucosal injury were common including: pyloric gland metaplasia (70% vs. 48%, P=0.01) and intestinal metaplasia (24% vs. 6%, P<0.01).	28622182
Inflammation, PMF Regimen	Altered Intercellular Communication	Our data indicate that older age and high JAK2V617 allele burden are major determinants of inflammation in PMF, and are associated with disease progression.	28622624
Inflammation, Giant Cell Arteritis, Autoimmune Disorder, CTCAE	Altered Intercellular Communication	Giant cell arteritis is a systemic autoimmune disorder which involves inflammation of medium to large vessels.	28623469
Mitochondrial Damage, Inflammation, Dermatomyositis, Impaired	Altered Intercellular Communication	IFN-b-induced reactive oxygen species and mitochondrial damage contribute to muscle impairment and inflammation maintenance in dermatomyositis.	28623559
Inflammation, Demographics Domain, Autoimmune Diseases, physiopathological, Dermatomyositis	Altered Intercellular Communication	Dermatomyositis (DM) is an autoimmune disease associated with enhanced type I interferon (IFN) signalling in skeletal muscle, but the mechanisms underlying muscle dysfunction and inflammation perpetuation remain unknown.	28623559
Abnormality of mitochondrial metabolism, Myositis	Altered Intercellular Communication	In addition, mitochondrial dysfunctions increase ROS production that drive type I IFN-inducible gene expression and muscle inflammation, and may thus self-sustain the disease.	28623559
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	These results suggest that the bowel inflammation observed in UC may have a causative effect of initiation of the immune response to the skin and development of the bullous skin lesions in LAGBD.	28623863
Inflammation	Altered Intercellular Communication	Our results provide evidence for MCP-1 involvement in the development of PVVs and indicate that inflammation could be implicated in the pathogenesis of this condition.	28623996
Communicable Diseases, Diverticulitis, Inflammation, Crohn Disease	Altered Intercellular Communication	Diverticulitis (DD) and Crohn's disease (CD) have overlapping features including bowel structuring, inflammation, and infection.	28624054
Inflammation, Myocardial	Altered Intercellular Communication	The functions of these proteins relate to myocardial stress, inflammation, pulmonary vascular cellular dysfunction and structural dysregulation, iron status, and coagulation.	28624389
Inflammation	Altered Intercellular Communication	Network analysis showed that in HFrEF interactions between biomarkers were mostly related to cardiac stretch, whereas in HFpEF, biomarker interactions were mostly related to inflammation.	28624483
Inflammation	Altered Intercellular Communication	Biomarker profiles in patients with acute HFrEF were mainly related to cardiac stretch and in HFpEF related to inflammation.	28624483
Cognitive, Nerve Degeneration	Altered Intercellular Communication	Brain inflammaging is increasingly considered as contributing to age-related cognitive loss and neurodegeneration.	28624504
Inflammation	Altered Intercellular Communication	We concluded that air pollution exposure was associated with systemic inflammation, oxidative stress and elevated blood pressure.	28624750
Inflammation, Metallosis	Altered Intercellular Communication	Only recently, however, it has the issue of metal-bone breakdown secondary to metal corrosion in situ come to light, raising concerns of possible long-term complications from the resulting metallosis and inflammation of spinal tissues.	28624897
Inflammation, Asthenia, Diarrhea, Exanthema	Altered Intercellular Communication	The most frequent AEs were diarrhea (94.9%), mucosal inflammation (64.1%), asthenia (53.8%) and rash (53.8%).	28625629
Inflammation, Craniosynostosis, Bacterial Infections	Altered Intercellular Communication	These findings suggest that IgD might contribute to enhancement mucosal immunity or inflammation or respond to bacterial infections in patients with CRS, especially CRSsNP.	28625807
ARCN1 gene, Pneumonitis	Altered Intercellular Communication	Individuals with COPD exposed to biomass burning demonstrated increased pulmonary inflammation and a reduction in the FEV1/FVC ratio, regardless of their engagement in PR.	28625881
Inflammation, Hyperplasia	Altered Intercellular Communication	Slight epidermal hyperplasia, dilated superficial thin-walled vessels and minimal to mild inflammation were seen in each.	28627021
Communicable Diseases, Hepatitis	Altered Intercellular Communication	These results suggest that the rs9514828 allele T may predispose to the liver inflammation in chronic HBV infection, and the rs9514828 and rs12583006 polymorphisms may combinatorially confer susceptibility to chronic HBV infection and resolution of the infection, possibly not through direct effect on serum BAFF levels.	28627389
Inflammation, Obesity	Altered Intercellular Communication	Dietary Red and Processed Meat Intake and Markers of Adiposity and Inflammation: The Multiethnic Cohort Study.	28628401
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The potential influence of dietary factors on inflammation is important for cancer prevention.	28628401
Inflammation, Obesity	Altered Intercellular Communication	The current data suggest that the amount of excess body weight or the degree of adiposity may mediate the relations between dietary red and processed meat intake and serum biomarkers associated with obesity and inflammation.	28628401
Hepatosplenomegaly, Inflammation, Acne, Arthritis, Infectious, Pyoderma Gangrenosum, Pancytopenia, PAPPA gene, Arthritis, Failure (biologic function)	Altered Intercellular Communication	It has a phenotype distinct from classical pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome that includes severe systemic and cutaneous inflammation, hepatosplenomegaly, arthritis without sequelae, pancytopenia and failure to thrive.	28628471
Inflammation, Memory Loss, Depression, CTCAE	Altered Intercellular Communication	Depression, inflammation, and memory loss among Mexican Americans: analysis of the HABLE cohort.	28629481
Inflammation, Depression, CTCAE	Altered Intercellular Communication	This study explored the combined impact of depression and inflammation on memory functioning among Mexican-American adults and elders.	28629481
Inflammation	Altered Intercellular Communication	Among DepE positive, those who were high in inflammation (3rd tertile) were found to perform significantly worse on WMS-III LM I (F = 4.75, p = 0.003), WMS-III LM II (F = 8.18, p < 0.001), and CERAD List Learning (F = 17.37, p < 0.001) when compared to those low on inflammation (1st tertile).	28629481
Inflammation, millicurie	Altered Intercellular Communication	The combination of DepE positive and highest tertile of inflammation was associated with increased risk for MCI diagnosis (OR = 6.06; 95% CI = 3.9-11.2, p < 0.001).	28629481
Inflammation	Altered Intercellular Communication	Presence of elevated inflammation and positive DepE scores increased risk for worse memory among Mexican-American older adults.	28629481
Inflammation, millicurie	Altered Intercellular Communication	Additionally, the combination of DepE and high inflammation was associated with increased risk for MCI diagnosis.	28629481
Inflammation, Depression, CTCAE	Altered Intercellular Communication	This work suggests that depression and inflammation are independently associated with worse memory among Mexican-American adults and elders; however, the combination of both increases risk for poorer memory beyond either alone.	28629481
Inflammation	Altered Intercellular Communication	This may allow increased sensitivity for early diagnosis of synovial inflammation, monitoring of its dynamic changes under therapy and evaluation of true imaging remission.	28629689
Inflammation, metabolic disturbance, Obesity	Altered Intercellular Communication	Oxidative stress and inflammation are related to obesity, but the influence of metabolic disturbances on these parameters and their relationship with endoplasmic reticulum (ER) stress is unknown.	28630460
Inflammation, Stomach Carcinoma	Altered Intercellular Communication	Both bacterial virulence factors and host chronic inflammation are thought to promote gastric cancer development.	28631561
Inflammation, Stomach Carcinoma, Neoplasms	Altered Intercellular Communication	These results suggested that dysregulation of follicular helper T subsets in gastric cancer patients, characterized by increased Th1-follicular helper T cells, contributed to inflammation and tumor development.	28631561
Inflammation, Depression, CTCAE, Cerebrovascular accident	Altered Intercellular Communication	Depression is a common complication after stroke, and inflammation may be a pathophysiological mechanism.	28632121
Inflammation, Depression, CTCAE, Cerebrovascular accident	Altered Intercellular Communication	This suggests that inflammation contributes differently to the development of depression after stroke depending on the time of onset.	28632121
Sepsis, Fever, CTCAE, Inflammatory dermatosis	Altered Intercellular Communication	We report a case of a 59-year-old man who presented with fever, sepsis, and left cervicothoracic cutaneous inflammation 13 months after implantation of Jarvik 2000 device.	28632696
Inflammation, Neoplasms, Communicable Diseases, Traumatic injury, Facial paralysis	Altered Intercellular Communication	Facial nerve paralysis can occur due to infection, inflammation, trauma, surgery, and tumors.	28632885
Necrotizing granulomatous inflammation, Cutaneous nodular amyloidosis, Sarcoidosis	Altered Intercellular Communication	Nodular cutaneous amyloidoma of the extremity secondary to chronic granulomatous inflammation in setting of sarcoidosis.	28632948
Inflammation, Hypertension, CTCAE, Traumatic injury, Diabetes Mellitus	Altered Intercellular Communication	Soft tissue amyloidomas on the extremities have been associated with chronic inflammation, particularly when accompanied by AA-type amyloid deposition as seen in local trauma, surgery, hypertension and diabetes.	28632948
Necrotizing granulomatous inflammation, Sarcoidosis	Altered Intercellular Communication	We hypothesize that this process developed secondary to the chronic granulomatous inflammation of sarcoidosis.	28632948
Paraneoplastic Endocrine Syndromes, Neoplasms	Altered Intercellular Communication	The majority of these tumors are found incidentally during screening colonoscopies and rarely are associated with symptoms of hormonal syndrome, even during the advanced stage.	28633725
Inflammation	Altered Intercellular Communication	The specific mechanism for its occurrence is still not entirely clear, and it is believed at present that platelet activation and inflammation play a pivotal role in developing no-reflow.	28633762
Inflammation, Lymphopenia	Altered Intercellular Communication	Both increased mean platelet volume (MPV), which is a platelet activation marker, and lymphopenia, which is an inflammation marker, have been linked to adverse events and poor prognosis after STEMI.	28633762
Inflammation, Tooth Loss	Altered Intercellular Communication	Diet-borne systemic inflammation is associated with prevalent tooth loss.	28633943
Inflammation, Tooth Loss	Altered Intercellular Communication	The deleterious effect of cariogenic dietary patterns on tooth loss is well characterized, but the contribution of diet-borne systemic inflammation to loss of teeth remains uncharted.	28633943
Inflammation, Nasal Polyps, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis with nasal polyps (CRSwNP) has been categorized into 2 subtypes in the Asian population: eosinophilic chronic rhinosinusitis (ECRS; similar to CRSwNP in Western countries) and non-ECRS (characterized by inflammation dominated by T-helper cell type 1).	28634018
Infection	Altered Intercellular Communication	SIRT3 deficiency has been reported to promote chronic inflammation-related disorders, but whether SIRT3 impacts on innate immune responses and host defenses against infections remains essentially unknown.	28634345
Sepsis, Inflammation	Altered Intercellular Communication	This finding may underlie the adverse cardiovascular events in patients admitted with sepsis, possibly requiring alteration of antiplatelet regimen during the inflammation period.	28635374
Inflammation, Retinitis Pigmentosa	Altered Intercellular Communication	Chronic inflammation is involved in retinitis pigmentosa (RP).	28636270
Inflammatory Bowel Diseases, Primary malignant neoplasm, Gastrointestinal inflammation	Altered Intercellular Communication	Inflammatory bowel disease (IBD) is characterized by recurrent or chronic inflammation of the gastrointestinal tract, which results in increased risk of developing cancer.	28637107
Inflammation, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	The pathogenesis of non-alcoholic fatty liver disease (NAFLD) is attributed to a "multi-hits hypothesis" involving insulin resistance, oxidative stress and inflammation.	28637594
Inflammation	Altered Intercellular Communication	NR4A3 expression is also increased at sites of neutrophilic inflammation in a human model of intradermal inflammation.	28637666
Fibrosis Assessment, Retractile Mesenteritis, Orbital Pseudotumor	Altered Intercellular Communication	BACKGROUND Sclerosing mesenteritis (SM) is a rare idiopathic inflammation and fibrosis of the mesentery.	28638005
Inflammation, Osage language, Hypoxemia, Bipolar Disorder, Sleep Apnea, Obstructive	Altered Intercellular Communication	This study examined the association between depressive symptoms, as well as depressive symptom dimensions, and three candidate biological pathways linking them to Obstructive sleep apnea (OSA): (1) inflammation; (2) circulating leptin; and (3) intermittent hypoxemia.	28639107
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	However, the exact factors that contribute to chronic inflammation and subsequently fibrosis progression are still unknown.	28639412
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	PET/MRI for evaluating subclinical inflammation of ulcerative colitis.	28640521
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	To explore the utility of integrated positron emission tomography (PET) / magnetic resonance imaging (MRI) for evaluating subclinical inflammation in patients with ulcerative colitis (UC).	28640521
Inflammation	Altered Intercellular Communication	Qualitative MRI score, PET activity grade, and PET/MRI score were also significantly higher in the colonic segments with active inflammation (P < 0.05).	28640521
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	PET/MRI is a potentially useful tool in identifying subclinical inflammation in patients with UC.	28640521
Inflammation, Neuropathogenesis, Trauma, Nervous System	Altered Intercellular Communication	They produce cytokines/chemokines and viral proteins that promote inflammation and neuronal damage, playing a key role in HIV neuropathogenesis.	28640909
Inflammation, Weight decreased, Acute inflammation	Altered Intercellular Communication	C5BL/6 female mice receiving dextran sodium sulfate in their drinking water develop an acute inflammatory colitis within 7d, with weight loss, histopathologic signs of inflammation, and colonic expression of inflammatory cytokines.	28641125
Inflammation, Dental Plaque	Altered Intercellular Communication	Contrast extravasation rate, or Ktrans, derived from kinetic modeling of adventitial enhancement, has been correlated with plaque neovascularization and inflammation.	28641819
Inflammation, Electrocardiogram: myocardial infarction (finding)	Altered Intercellular Communication	Ferumoxytol-enhanced magnetic resonance imaging assessing inflammation after myocardial infarction.	28642288
Inflammation, Edema, Cardiac	Altered Intercellular Communication	This observed pattern of cellular inflammation is distinct, and provides complementary information to the more prolonged myocardial oedema detectable using T2 mapping.	28642288
Inflammation, Inflammatory disorder	Altered Intercellular Communication	GlycA is a new composite measure of systemic inflammation and a predictor of many inflammatory diseases.	28642810
Cytomegalovirus Infections, Asthma, Inflammation	Altered Intercellular Communication	We conclude that CMV infection is associated with asthma and may contribute to the pathogenesis of asthmatic inflammation.	28643373
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	The osteoarthritis (OA) progression is now considered to be related to inflammation.	28643466
Inflammation, Oral Manifestations	Altered Intercellular Communication	NO2, which is poorly soluble in water, penetrates deep into the bronchial tree, producing asthmatic manifestations such as inflammation and increased mucus production as a result of high gaseous concentrations in the lung parenchyma.	28644724
Cerebrovascular Disorders, Inflammation	Altered Intercellular Communication	Circulation inflammation markers such as high-sensitive C-reactive protein (hsCRP) and lipoprotein-associated phospholipase A2 (Lp-PLA2) are considered as predictors of cerebral and cardiac vascular diseases.	28644968
Upper Respiratory Infections	Altered Intercellular Communication	This study suggested low ambient temperature, fine PM, and coarse PM might elevate the levels of respiratory inflammation.	28645522
Inflammation, Asthma	Altered Intercellular Communication	Biomarkers of airway and systemic inflammation in obese asthmatic paediatric patients.	28645880
Airway structure, Inflammation, Asthma	Altered Intercellular Communication	It is thought that airway inflammation is more common in obese asthmatic patients because inflammation is harder to control and does not respond well to glucocorticoid treatment.	28645880
Inflammation, Asthma, Obesity	Altered Intercellular Communication	This study's aim was to investigate the effect of obesity on airway and systemic inflammation in children with asthma and to identify the biomarkers that play a role in this inflammation.	28645880
Inflammation, Asthma	Altered Intercellular Communication	Larger studies with sputum and BAL examinations are required to determine the potential of biomarkers for identifying inflammation in obese asthmatic children.	28645880
Hypertension, CTCAE	Altered Intercellular Communication	Immuno-inflammation plays a major role in the process of hypertension.	28646855
Inflammation	Altered Intercellular Communication	Mice lacking cIAP1 and either cIAP2 or XIAP die in utero, and myeloid lineage-specific deletion of all IAPs causes sterile inflammation, but their role in the skin is unknown.	28647349
Cessation of life, Dermatitis	Altered Intercellular Communication	We generated epidermal-specific IAP-deficient mice and found that combined genetic deletion of cIAP1 (epidermal knockout [EKO]) in keratinocytes and ubiquitous cIAP2 deletion (cIap1EKO/EKO.cIap2-/-) caused profound skin inflammation and keratinocyte death, lethal by postpartum day 10.	28647349
Inflammation	Altered Intercellular Communication	This induced a toxic epidermal necrolysis-like local inflammation, which mirrored the phenotype seen in cIap1EKO/EKO.cIap2-/- mice.	28647349
Dermatitis	Altered Intercellular Communication	This work therefore refines our molecular understanding of inflammatory signaling in the skin and defines potential targets for treating skin inflammation.	28647349
Dermatitis	Altered Intercellular Communication	This work therefore refines our molecular understanding of inflammatory signaling in the skin and defines potential targets for treating skin inflammation.	28647349
Degenerative polyarthritis, Inflammation, Synovitis	Altered Intercellular Communication	Despite this the recent studies are shown synovitis and low inflammation to have a role in OA pathophysiology.	28647559
Inflammation, Atherosclerosis	Altered Intercellular Communication	Associations of Cigarette Smoking With Subclinical Inflammation and Atherosclerosis: ELSA-Brasil (The Brazilian Longitudinal Study of Adult Health).	28647689
Inflammation, Atherosclerosis	Altered Intercellular Communication	We examined the association of smoking status, burden, time since quitting, and intensity, with markers of inflammation and subclinical atherosclerosis.	28647689
Inflammation, Carotid Intima-Media Thickness, Atherosclerosis	Altered Intercellular Communication	Strong associations were observed between smoking status, burden, and intensity with inflammation (hsCRP) and subclinical atherosclerosis (carotid intima-media thickness, ankle-brachial index, CAC).	28647689
Malignant neoplasm of urinary bladder	Altered Intercellular Communication	Integrative Assessment of Pretreatment Inflammation-, Nutrition-, and Muscle-Based Prognostic Markers in Patients with Muscle-Invasive Bladder Cancer Undergoing Radical Cystectomy.	28647740
Inflammation	Altered Intercellular Communication	The present BRONJ POE revealed the rapid progress of bony wound healing through increased molecular signaling for inflammation, angiogenesis, and osteogenesis compared to the control.	28647850
Inflammation	Altered Intercellular Communication	LM disclosed a low-grade chronic inflammation and birefringent particles in most sections.	28648703
Refractory anemias, Inflammation	Altered Intercellular Communication	Synovial inflammation is a major feature of RA and is associated with leukocyte recruitment.	28648867
Bacterial peritonitis	Altered Intercellular Communication	The in-vivo effects were evaluated by circulatory inflammation-associated cytokine levels in mice with septic peritonitis induced by cecal ligation and puncture (CLP) operation.	28648928
Drug Eruptions, Inflammation	Altered Intercellular Communication	The thymus and activation-regulated chemokine (TARC) level in serum at an early stage of a drug eruption is a prognostic biomarker of severity of systemic inflammation.	28648978
Drug Eruptions, Inflammation	Altered Intercellular Communication	Serum TARC levels correlate well with indicators of systemic inflammation and of disease severity among patients with a drug eruption except SJS/TEN.	28648978
Drug Eruptions, Inflammation	Altered Intercellular Communication	Serum TARC may be a prognostic biomarker of severity of inflammation in drug eruptions.	28648978
Inflammation, Brain Injuries	Altered Intercellular Communication	Yet, emerging evidence suggests that viral suppression will inadequately control inflammation and mitigate risk for progressive brain injury.	28650401
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Adipose tissues secrete adipokines, peptides with potent effects modulating fibrosis, inflammation, and vascular homeostasis.	28651038
Inflammation	Altered Intercellular Communication	Clinical disease activity consistently declined, but faecal calprotectin and circulating markers of inflammation did not.	28651829
Inflammation, Hematoma, Atrial Premature Complexes	Altered Intercellular Communication	If pregnancy continues, these haematomas may act as a source of oxidative stress, promoting senescence and weakening of the membranes, and stimulating inflammation in the uterine wall and premature contractions.	28651899
Uremia, Inflammation	Altered Intercellular Communication	Inflammation and uremia negatively impact immune function in this population, but specific pathways involved in TB immunity have not been identified.	28651949
Inflammation	Altered Intercellular Communication	Surprisingly, neither the gd phenotype nor its function was associated with plasma markers of inflammation or microbial translocation.	28651949
Brain Hypoxia, Inflammation, Reperfusion Injury, Trauma, Nervous System	Altered Intercellular Communication	Transient cerebral hypoxia may induce neuronal injury through an ischemia-reperfusion (I/R) response, with a subsequent activation of inflammation and coagulation-fibrinolysis.	28652057
Inflammation, Pain Distress Question	Altered Intercellular Communication	Proteins associated with DD tended to be related to inflammation (eg, cystatin C) regardless of pain status.	28652204
Inflammation, Nerve injury	Altered Intercellular Communication	This study shows that CSF can be used to study mechanisms underlying painful DD in humans, and suggests that while painful DD is associated with nerve injury, inflammation itself is not sufficient to develop LBP.	28652204
Inflammation, Nerve injury, Pain Distress Question	Altered Intercellular Communication	While DD was related to inflammation regardless of pain status, painful degeneration was associated with markers linked to nerve injury.	28652204
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	These results uncover a possible pathway for LTF-ICs perpetuating local inflammation and contributing to the pathogenesis of autoimmune diseases by triggering activation of infiltrating monocytes or tissue macrophages in vivo.	28652573
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Markers of inflammation and iron status were positively associated with serum hepcidin level, regardless of CKD stage.	28652624
Acute cholangitis, Cholangitis	Altered Intercellular Communication	In another case, signs of bile duct inflammation caused by acute cholangitis were evident.	28652659
Granulomatous inflammation, Gossypiboma	Altered Intercellular Communication	In conclusion, based on this case, gossypiboma (or granulomatous inflammation in response to foreign bodies) should be also considered in differential diagnosis of intrathoracic lymph nodes with PET positivity in a previously operated patient.	28653494
Inflammation, Prostate carcinoma	Altered Intercellular Communication	Periprostatic adipose inflammation is associated with high-grade prostate cancer.	28653675
Inflammation, Prostate carcinoma, Obesity	Altered Intercellular Communication	Obesity, a cause of subclinical inflammation, is associated with increased risk of high-grade prostate cancer (PC) and poor outcomes.	28653675
Inflammation, Aggressive behavior, Obesity	Altered Intercellular Communication	Whether inflammation occurs in periprostatic white adipose tissue (WAT), and contributes to the negative impact of obesity on PC aggressiveness, is unknown.	28653675
Inflammation	Altered Intercellular Communication	The primary objective was to examine the prevalence of periprostatic WAT inflammation defined by the presence of crown-like structures (CLS-P) as detected by CD68 immunohistochemistry.	28653675
Inflammation, Neoplasms	Altered Intercellular Communication	Periprostatic WAT inflammation was identified in 49.7% of patients and associated with higher BMI (P=0.02), larger adipocyte size (P=0.004) and Gleason grade groups IV/V tumors (P=0.02).	28653675
Inflammation	Altered Intercellular Communication	The relationship between WAT inflammation and high Gleason grade remained significant after adjusting for BMI (P=0.04).	28653675
Inflammation, Acute lymphocytic leukemia	Altered Intercellular Communication	Young adult survivors of childhood acute lymphoblastic leukemia show evidence of chronic inflammation and cellular aging.	28654149
Inflammation, Acute lymphocytic leukemia	Altered Intercellular Communication	The authors investigated whether young adult survivors of childhood acute lymphoblastic leukemia (ALL) have a biologic phenotype of cellular ageing and chronic inflammation.	28654149
Inflammation, Acute lymphocytic leukemia	Altered Intercellular Communication	Asymptomatic young adult survivors of childhood ALL demonstrate a biologic profile of chronic inflammation and telomere attrition, consistent with an early onset of cellular processes that drive accelerated aging.	28654149
methyldopa, Inflammation	Altered Intercellular Communication	It has been suggested that systemic inflammation increases the risk of age-related macular degeneration (AMD).	28655032
methyldopa, Malignant Peripheral Nerve Sheath Tumor, Inflammation	Altered Intercellular Communication	Our results suggest that patients with MPNs are at increased risk of AMD, supporting the possibility that systemic inflammation is involved in the pathogenesis of AMD.	28655032
Inflammation	Altered Intercellular Communication	We investigated the impact of specific neuroinflammatory markers on human neurons to identify potential therapeutic targets for neuroprotection against chronic inflammation.	28655310
Tubulitis Assessment, Interstitial inflammation	Altered Intercellular Communication	Indication biopsies after immunosuppression reduction showed an increase in tubulitis and interstitial inflammation score compared to those at the time of the PVN diagnosis.	28655392
Tubulitis Assessment, Viremia, Interstitial inflammation	Altered Intercellular Communication	Surveillance biopsies 1 year after transplantation revealed resolution of interstitial inflammation and tubulitis accompanied by clearance of BK viremia in 4 patients (50%), including 1 patient with rejection.	28655392
Interstitial inflammation	Altered Intercellular Communication	One patient showed residual interstitial inflammation after viral clearance.	28655392
Tubulitis Assessment, Interstitial inflammation	Altered Intercellular Communication	PVN-associated interstitial inflammation and tubulitis cannot be differentiated morphologically from T-cell-mediated tubulointerstitial rejection.	28655392
Tubulitis Assessment, Interstitial inflammation	Altered Intercellular Communication	Significant interstitial inflammation and tubulitis in PVN under low-dose immunosuppression might represent immune reconstitution injury, which is reduced after successful BKV clearance from the serum and kidney.	28655392
Eosinophilic esophagitis, Esophagitis, Immune-mediated, "Extra-osseous Ewings sarcoma	Altered Intercellular Communication	Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease characterized by esophageal inflammation and dysfunction.	28655543
APP gene, Inflammation	Altered Intercellular Communication	Inflammation is an important process in AAA formation and increases levels of oxidative stress.	28655550
Crohn Disease, Inflammation	Altered Intercellular Communication	Routine clinical care for Crohn's disease (CD) outpatients does not cover the assessment of body composition (BC); although this disease (because of inflammation, surgeries, lack of physical activity and appetite) may have a severe impact on lean body mass.	28656973
Inflammation, Chronic inflammation	Altered Intercellular Communication	This may reflect a switch from acute to chronic inflammation, where chronic inflammation is reflected in the serum after the acute phase response subsides.	28657165
Calcified (qualifier), Inflammation, Ulceration, CTCAE, Pain Distress Question	Altered Intercellular Communication	Subcutaneous calcifications can lead to complications, including pain, inflammation, ulceration and immobilization.	28660279
Pituitary Adenoma	Altered Intercellular Communication	Normal hormonal status was found, consistent with the diagnosis of non-functioning pituitary adenoma.	28660992
Inflammation	Altered Intercellular Communication	Evaluation of ultrasmall superparamagnetic iron-oxide (USPIO) enhanced MRI with ferumoxytol to quantify arterial wall inflammation.	28662398
Inflammation, Dental Plaque, atherosclerotic	Altered Intercellular Communication	Inflammation in atherosclerotic plaques is an important determinant of plaque vulnerability, and can be detected non-invasively using ultra-small superparamagnetic iron-oxide (USPIO) enhanced MRI.	28662398
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	As USPIO and 18F-FDG uptake in atherosclerotic plaque do not correlate in this cohort, these agents may visualize different pathophysiological aspects of plaque inflammation.	28662398
Inflammation, Disease	Altered Intercellular Communication	Our data showed that IL-20 is independently associated with RA disease activity and may be triggered by TLR ligands at local sites of inflammation.	28662439
Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	High triglycerides and low high-density lipoprotein cholesterol lipid profile in rheumatoid arthritis: A potential link among inflammation, oxidative status, and dysfunctional high-density lipoprotein.	28662934
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The interactions between inflammation and lipid profile in rheumatoid arthritis (RA) are poorly understood.	28662934
TG gene, Inflammation, Refractory anemias	Altered Intercellular Communication	Since recent findings suggest a role for TG and TG-rich lipoproteins (TRL) on inflammation, we aimed to evaluate a combined lipid profile characterized by high TG and low high-density lipoprotein cholesterol levels (TGhighHDLlow) in RA.	28662934
Refractory anemias, Inflammation, physiopathological	Altered Intercellular Communication	The TGhighHDLlow profile is associated with systemic inflammation, decreased PON1 activity, and poor clinical outcome on TNFa blockade in RA, suggesting a role of TRL and HDL dysfunction as the missing link between inflammation and lipid profile.	28662934
Inflammation, Atherosclerosis	Altered Intercellular Communication	We aimed to analyse the association between inflammation and subclinical atherosclerosis in HIV patients with low Framingham risk score.	28664622
Carotid Atherosclerosis, Inflammation	Altered Intercellular Communication	Well-controlled HIV patients with low Framingham risk score have a high prevalence of subclinical carotid atherosclerosis, and the main risk factors are age and inflammation.	28664622
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In kidney transplant recipients, the addition of 2 ug/day paricalcitol to RAS inhibition lowers IL-6 and TGF-b concentrations, which may be beneficial for reducing graft inflammation and fibrosis.	28664839
Inflammation, Hyperbilirubinemia, Liver Dysfunction	Altered Intercellular Communication	We present the case of a 6-year-old child with severe hyperbilirubinemia due to congestive liver dysfunction, complicated by persistent inflammation, immunosuppression and catabolism syndrome (PICS).	28665446
Nasal Polyps	Altered Intercellular Communication	We evaluated the prognostic value of nasal cytology and clinical factors in predicting nasal polyp (NP) development in patients with history of nonallergic chronic sinonasal inflammation.	28665504
Inflammation	Altered Intercellular Communication	According to the inclusion criteria we enrolled 84 cases with persistent eosinophilic nonallergic sinonasal inflammation (group A) and 106 cases with neutrophilic inflammation (group B), both without evidence of NPs at the baseline.	28665504
Inflammation	Altered Intercellular Communication	We considered as controls 105 patients affected by nonallergic noninfectious vasomotor rhinitis without evidence of inflammation at nasal cytology (group C).	28665504
Aggressive course, Eosinophilic inflammation	Altered Intercellular Communication	Our data confirm that detection of nasal eosinophilic inflammation represents an early marker for identification of a more aggressive inflammatory phenotype.	28665504
Inflammation	Altered Intercellular Communication	Diet quality, inflammation, and the ankle brachial index in adults with or without cardiometabolic conditions.	28666597
Granulomatous inflammation, Anxiety, CTCAE 3.0	Altered Intercellular Communication	Analyzing tissue specimens with frozen section has been shown in the past to demonstrate granulomatous inflammation and yeast forms of the organism; however, as demonstrated in this patient, the presence of pseudoepitheliomatous cells may deceptively appear as malignant, causing substantial concern and anxiety.	28666674
Inflammation	Altered Intercellular Communication	Additionally, the numbers of CD4+ and Foxp3+ T cells as well as the expression of IL-10, TGF-b1, FOXP3 and INF-g were positively correlated with the degree of H. pylori density and chronic inflammation.	28666843
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	The Contribution of Inflammation to the Development of Hypertension Mediated by Increased Arterial Stiffness.	28666991
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	The mechanisms underlying the possible contribution of chronic inflammation to the development of hypertension remain unclear.	28666991
Inflammation, Hypertension, CTCAE, Abnormality of the vasculature	Altered Intercellular Communication	We examined the longitudinal association of inflammation with the progression of vascular and/or renal abnormalities in the development of hypertension.	28666991
Arterial Stiffness, Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	In middle-aged Japanese men without hypertension at study baseline, long-term active inflammation appears to be associated with a longitudinal increase of arterial stiffness.	28666991
Arterial Stiffness, Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Thus, systemic inflammation may play a role in the pathogenesis of hypertension by the progression of arterial stiffness.	28666991
Inflammation, Osteopenia	Altered Intercellular Communication	Periodontal diseases manifest by the formation of deep pockets between the gingiva and teeth where multispecies bacterial biofilms flourish, causing inflammation and bone loss.	28667248
Inflammation	Altered Intercellular Communication	Moreover, Itgb6 -/- mice display increased periodontal inflammation compared to wild-type mice.	28667248
Inflammation, Periodontal Diseases	Altered Intercellular Communication	We hypothesized that bacterial biofilms present in the periodontal pockets suppress avb6 integrin levels in periodontal disease and that this change aggravates inflammation.	28667248
Inflammation, Carcinogenesis	Altered Intercellular Communication	In conclusion, this study suggests that obesity-related systemic low-grade inflammation may play an important role in the early stages of colorectal carcinogenesis.	28667300
Cessation of life, Inflammation	Altered Intercellular Communication	Analysis of sWAT from mice of various ages showed senescence, persistent DNA damage and cell death that preceded macrophage infiltration, and systemic inflammation.	28667315
Hereditary Autoinflammatory Diseases, Inflammation	Altered Intercellular Communication	It is a rare condition, particularly in the pediatric population, and has recently been proposed to be an autoinflammatory disease that occurs due to innate immune system dysfunction, involving several cytokines, which causes abnormally increased inflammation.	28668093
Abscess, pathologic fistula, Inflammation, Edema	Altered Intercellular Communication	Abscesses, fistulous or sinus tracts, signal alterations and contrast enhancement in keeping with an inflammation and edema in the perianal region were recorded.	28668427
Perianal	Altered Intercellular Communication	In 10 of these 16 patients there was also extensive inflammatory signal alterations in perianal and/or perineal soft tissues.	28668427
Abscess	Altered Intercellular Communication	There were abscesses in labium majus in two patients and in one patient there were perineal abscesses with accompanying inflammatory signal alterations.	28668427
Perianal	Altered Intercellular Communication	There were only inflammatory signal alterations with contrast enhancement in perianal or subcutaneous tissues.	28668427
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Inflammation is an important regulator of osteoarthritis (OA), but the molecular and cellular mechanisms regulating this process are not well defined.	28668542
Degenerative polyarthritis, Acute and chronic inflammation	Altered Intercellular Communication	Our results indicate that NK cells from the synovium of patients with OA, which present an immunoregulatory non-cytotoxic phenotype, show different phenotype comparing with NK cells from peripheral blood, especially expressing granzyme A, a pro-inflammatory molecule which may contribute to the establishment of chronic articular inflammation in this type of patients.	28668542
Demographics Domain, Diabetes Mellitus, Neurogenic arthropathy, Osteopenia, Peripheral Neuropathy	Altered Intercellular Communication	Inflammation-mediated foot osteopenia may play a pivotal role in the etiogenesis, pathogenesis, and therapeutic outcomes in individuals with diabetes mellitus (DM), peripheral neuropathy (PN), and Charcot neuroarthropathy (CN).	28668579
Inflammation, Metabolic Diseases, Primary malignant neoplasm	Altered Intercellular Communication	Osteopontin is a secreted extracellular glyco-phosphoprotein that has been associated with inflammation, metabolic disorders and cancer.	28668580
Carcinogenesis, Gastrointestinal inflammation	Altered Intercellular Communication	Thrombospondin-1 (TSP1) is correlated with carcinogenesis occurring in cases of intestinal inflammation.	28668845
Inflammation, Vasospasm, Vascular System Injuries	Altered Intercellular Communication	Severe vasospasm was thought to have occurred because the vascular injury caused by the stent retriever in the vessel had a marked inflammation background.	28669652
Diabetes Mellitus, Non-Insulin-Dependent, Immune-mediated	Altered Intercellular Communication	The aim of this trial was to determine the efficacy of a resistant dextrin on immune-mediated inflammation and hypothalamic-pituitary-adrenal axis in women with type 2 diabetes mellitus (T2DM).	28669666
Inflammation, Fibrosis Assessment, Hypertrophy	Altered Intercellular Communication	MiR-21 is a fibrosis-associated miRNA and promotes inflammation in LF tissue by activating IL-6 expression, leading to LF fibrosis and hypertrophy.	28669725
Pain Distress Question, Sinusitis	Altered Intercellular Communication	There was no difference in the sinus inflammation scores in CT findings, based on the presence of pain.	28670951
Inflammation, Ocular Hypotension, Serous choroidal detachment, Hyphema, Unspecified visual loss	Altered Intercellular Communication	Complications included hypotony, IOP spike, hyphema, serous choroidal detachment, persistent inflammation, and vision loss.	28671927
Inflammation, Unspecified visual loss	Altered Intercellular Communication	At 3 months, inflammation was still present in 46% of eyes and vision loss of at least 1 line was present in 41% of eyes.	28671927
Inflammation	Altered Intercellular Communication	Arterial wall thickening, stimulated by low-grade systemic inflammation, underlies many cardiovascular events.	28673375
Cessation of life, Inflammation, Atherosclerosis	Altered Intercellular Communication	These results support the hypothesis that a pro-inflammatory diet increases systemic inflammation leading to development and progression of atherosclerosis and eventual ASVD-related death.	28673375
Inflammation, Movement Disorders, Parkinsonian Disorders, SLC12A3 gene	Altered Intercellular Communication	Parkinsonism, the most common movement disorder in NCC, is not related to specific localization of the lesions but the patients show widespread and large lesions, associated with inflammation and distortions of brain structures.	28673613
Inflammation, Hyperparathyroidism	Altered Intercellular Communication	Correction of 25-OH-vitamin D deficiency improves control of secondary hyperparathyroidism and reduces the inflammation in stable haemodialysis patients.	28673686
Inflammation	Altered Intercellular Communication	In terms of malnutrition-inflammation status, a decrease in C-reactive protein was noted, although other microinflammation parameters, such as activated monocytes (CD14+/CD16+ and CD 14++/CD16+) were unchanged.	28673686
Inflammation, Hepatobiliary Disorder, Injury of liver, Fibrosis Assessment	Altered Intercellular Communication	Vascular adhesion protein-1 (VAP-1) drives inflammation in liver disease, and provision of an antibody against VAP-1 blunts fibrosis in murine models of liver injury.	28674140
vascular inflammations, Atherosclerosis	Altered Intercellular Communication	Oxidative stress is involved in vascular inflammation, the process of atherosclerosis.	28674322
Inflammation, Arthritis	Altered Intercellular Communication	Dual energy CT iodine map for delineating inflammation of inflammatory arthritis.	28674965
Arthritis	Altered Intercellular Communication	* Dual-energy CT iodine mapping can delineate inflammation of peripheral inflammatory arthritis.	28674965
Inflammation, Microvascular Angina	Altered Intercellular Communication	Inflammation is one of the mechanisms underlying cardiac syndrome X (CSX).	28675064
syphilis infection, Intraocular inflammation, Uveitis	Altered Intercellular Communication	Uveitis (intraocular inflammation) usually occurs in the secondary or later stages of syphilis infection and is sight-threatening.	28675181
Inflammation, Fibrosis Assessment, Degenerative disorder, Aortic Valve Stenosis	Altered Intercellular Communication	Recent studies suggest that aortic stenosis is not a passive degenerative disease, but an active process involving several pathways, including lipid infiltration, chronic inflammation, fibrosis formation, osteoblast activation, and active valve mineralisation.	28675194
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	This article is part of a themed section on Targeting Inflammation to Reduce Cardiovascular Disease Risk.	28675448
Inflammation, Hypersensitivity	Altered Intercellular Communication	Mucosal inflammation, altered neuroendocrine activity and intraluminal metabolic processes may contribute to the development of visceral hypersensitivity.	28675524
Inflammation, Epilepsy	Altered Intercellular Communication	Processes implicating brain inflammation have been increasingly observed in epilepsy research.	28675559
Encephalomyelitis, Inflammation, Comorbidity, Epilepsy	Altered Intercellular Communication	Herein we discuss the progress on animal models of epilepsy and comorbidities that inform us on the potential role of inflammation in epileptogenesis and comorbidity pathogenesis in rodent models of West syndrome and the Theiler's murine encephalomyelitis virus (TMEV) mouse model of viral encephalitis-induced epilepsy.	28675559
Inflammation	Altered Intercellular Communication	The present study showed the epidemiology of frailty, and the strong connection to aging, increased CIMT, enhanced inflammation and decreased femoral neck BMD.	28675572
Inflammation, Atherosclerosis	Altered Intercellular Communication	These results suggested that preclinical atherosclerosis, inflammation and femoral neck BMD were potentially modifiable risk factors for frailty.	28675572
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Early subclinical inflammation in kidney transplants is associated with later graft fibrosis and dysfunction.	28675676
Inflammation, Dysbiosis	Altered Intercellular Communication	Increased gut permeability ("leaky gut") has been proposed as a potential contributor to age-related inflammation and gut dysbiosis.	28676292
Inflammation	Altered Intercellular Communication	To investigate the hypothesis that an aging-associated leaky gut is linked to the age-related inflammation and frailty.	28676292
Inflammation	Altered Intercellular Communication	These data suggest that a leaky gut may play a critical role in the development of age-related inflammation and frailty.	28676292
Inflammation, Malnutrition, Anemia	Altered Intercellular Communication	Anemia Is Correlated with Malnutrition and Inflammation in Croatian Peritoneal Dialysis Patients: A Multicenter Nationwide Study.	28676512
palladium, Inflammation, Malnutrition, Anemia	Altered Intercellular Communication	Malnutrition, inflammation, and anemia are common in peritoneal dialysis (PD) patients.	28676512
palladium, Malnutrition, Anemia	Altered Intercellular Communication	In this study, correlations between Malnutrition Inflammation Score (MIS), laboratory and anthropometric parameters, and anemia indices in Croatian PD patients were analyzed.	28676512
palladium, Inflammation, Malnutrition, Anemia	Altered Intercellular Communication	Our findings suggest that anemia is correlated with malnutrition and inflammation in Croatian PD patients.	28676512
Inflammation, Venous Thrombosis	Altered Intercellular Communication	Age-related diagnostic value of D-dimer testing and the role of inflammation in patients with suspected deep vein thrombosis.	28676651
Inflammation, Venous Thrombosis	Altered Intercellular Communication	Further research is required to decrypt the role of inflammation in the pathophysiology and diagnosis of venous thrombosis.	28676651
Inflammation, Obesity	Altered Intercellular Communication	Increased inflammation and oxidative stress associated with obesity can accelerate aging.	28676678
Degenerative polyarthritis	Altered Intercellular Communication	This study also supported the inflammation-induced DKK1 and OPG in OA pathogenesis.	28676900
Inflammation, Thrombosis	Altered Intercellular Communication	Recently, the mean platelet volume-to-lymphocyte ratio (MPVLR) has emerged as a novel and readily available marker of inflammation and thrombosis.	28678144
Inflammation, Atherosclerosis	Altered Intercellular Communication	Neighborhood characteristics influence DNA methylation of genes involved in stress response and inflammation: The Multi-Ethnic Study of Atherosclerosis.	28678593
group cohesion	Altered Intercellular Communication	Neighborhood social environment, a summary measure of aesthetic quality, safety, and social cohesion, was associated with methylation in 4 of the 7 stress-related genes (AVP, BDNF, FKBP5, SLC6A4) and 7 of the 11 inflammation-related genes (CCL1, CD1D, F8, KLRG1, NLRP12, SLAMF7, TLR1).	28678593
Pulmonary arterial hypertension, Polycyclic Hydrocarbons, Aromatic	Altered Intercellular Communication	Inflammatory signaling may play an important role in the pathogenesis of pulmonary arterial hypertension (PAH).	28678692
Inflammation, Non-alcoholic Fatty Liver Disease, Hyperferritinaemia	Altered Intercellular Communication	Hyperferritinaemia in NAFLD is often attributed to inflammation, while in other conditions ferritin closely reflects body iron stores.	28679028
Crohn Disease	Altered Intercellular Communication	Crohn's disease (CD) is a chronic inflammatory condition of the gastrointestinal tract.	28679179
Renal Insufficiency, Inflammation, Myalgia, Muscle Fibers	Altered Intercellular Communication	An acute bout of eccentric contractions (ECC) cause muscle fiber damage, inflammation, impaired muscle function (MF) and muscle soreness (MS).	28680370
Inflammation, Hypertrophy	Altered Intercellular Communication	However, assessment of its therapeutic activity can be challenging because of tumour enlargement associated with intratumoural inflammation.	28681063
Inflammation	Altered Intercellular Communication	The percentage of cases with PGII >=7.5 mg/L, as indication for antral inflammation, was higher than in controls: 58.6 versus 44.7%, P = 0.027.	28681188
Gastritis, Abdominal Pain	Altered Intercellular Communication	* Serum pepsinogens (PGs), non-invasive markers of gastric inflammation, were rarely utilized in assessing the association between H. pylori in pediatric abdominal pain of unknown origin.	28681188
Inflammation, Periodontitis	Altered Intercellular Communication	Platelets contribute to chronic inflammation, but their role in periodontitis is not well understood.	28681377
Inflammation, Abnormality of the vasculature	Altered Intercellular Communication	A potential contribution of psoriasin to vascular and epithelial abnormalities and inflammation in systemic sclerosis.	28681537
Inflammation, Sample Size Calculation, Abnormality of the vasculature	Altered Intercellular Communication	Our findings indicate a possible contribution of psoriasin to the development of clinical symptoms associated with vascular and epithelial abnormalities and inflammation in SSc, further supporting the roles of antimicrobial peptides in the SSc pathogenesis.	28681537
Inflammation, Rheumatism	Altered Intercellular Communication	Detection of synovial inflammation in rheumatic diseases using superb microvascular imaging: Comparison with conventional power Doppler imaging.	28681656
Refractory anemias, Inflammation, Metacarpophalangeal joint structure	Altered Intercellular Communication	Among the joint regions, the wrists and metacarpophalangeal joints were more sensitive to the detection of synovial inflammation using SMI in patients with RA.	28681656
Refractory anemias, Inflammation	Altered Intercellular Communication	SMI was more sensitive in detecting synovial inflammation than cPDI in patients with RA.	28681656
Osteomyelitis, Inflammation, Failure (biologic function)	Altered Intercellular Communication	Background and purpose - Treatment failure of osteomyelitis can result from genetic susceptibility, highlighting polymorphisms of the interleukin-1 (IL-1) family members, central mediators of innate immunity and inflammation.	28682145
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Prognostic Impact of Intra-abdominal/Pelvic Inflammation After Radical Surgery for Locally Recurrent Rectal Cancer.	28682968
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	However, it remains unclear whether intra-abdominal/pelvic inflammation after radical surgery for locally recurrent rectal cancer is relevant to its prognosis.	28682968
Pain Distress Question, Primary malignant neoplasm, Inflammation, Neoplasms	Altered Intercellular Communication	Age (p = 0.002), initial tumor stage (p = 0.03), pain associated with locally recurrent rectal cancer (p = 0.03), CEA level (p = 0.004), resection margin (p < 0.001), intra-abdominal/pelvic inflammation (p < 0.001), and surgery period (p = 0.045) were independent prognostic factors associated with overall survival, whereas CEA level (p = 0.01), resection margin (p = 0.002), and intra-abdominal/pelvic inflammation (p = 0.001) were associated with relapse-free survival.	28682968
Inflammation, Actual blood loss	Altered Intercellular Communication	A large amount of perioperative blood loss was the only factor associated with the occurrence of intra-abdominal/pelvic inflammation (p = 0.007).	28682968
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Intra-abdominal/pelvic inflammation after radical surgery for locally recurrent rectal cancer is associated with poor prognosis.	28682968
Fatty Liver, Inflammation, Obesity	Altered Intercellular Communication	The inflammatory kinases IKKe and TBK1 are elevated in obesity; their inhibition in obese mice reduces weight, insulin resistance, fatty liver and inflammation.	28683283
Communicable Diseases, Inflammation	Altered Intercellular Communication	CD4+ T cells secrete cytokines that promote inflammation and an anti-bacterial response in the gastric mucosa during infection.	28683359
Inflammation, Infection caused by Helicobacter pylori	Altered Intercellular Communication	The frequencies of IFNg and IL-17A+ cells correlated positively with inflammation in the antrum, but not the corpus, of H. pylori infected individuals.	28683359
Inflammation, Atherosclerosis	Altered Intercellular Communication	Free arachidonic acid (AA) is an important precursor of lipid mediators such as leukotrienes and prostaglandins that induces inflammation and is associated with atherosclerosis progression.	28683445
Communicable Diseases, Inflammation	Altered Intercellular Communication	Overall sensitivity was 80.5% and specificity 89.8%, and was not greatly impacted by inflammation or infection.	28683471
Inflammation, Demographics Domain, Diabetes Mellitus	Altered Intercellular Communication	Recent studies have pointed out a link among RDW, diabetes mellitus (DM) and inflammation.	28683798
Inflammation, Cachexia	Altered Intercellular Communication	We conclude that FO-enriched nutrition may improve the prognosis of patients with cancer cachexia and systemic inflammation (i.e., those with a mGPS of 1 or 2).	28684736
Cell Death, Kidney Failure, Acute, Interstitial inflammation, Injury of kidney	Altered Intercellular Communication	Acute kidney injury (AKI) is characterized by tubular cell death and interstitial inflammation.	28684863
Nasal inflammation	Altered Intercellular Communication	Glycyrrhetinic acid suppressed hmgb1 release by up-regulation of Sirt6 in nasal inflammation.	28685526
Inflammation, Chronic Fatigue Syndrome	Altered Intercellular Communication	This study elucidates the question of whether chronic inflammation in the jawbone contributes to the development of Chronic Fatigue Syndrome (CFS).	28685531
Inflammation, Chronic Fatigue Syndrome	Altered Intercellular Communication	Constituting a hidden source of silent inflammation FDOJ may represent a hitherto unknown cause for the development of CFS.	28685531
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Our exploratory analysis showed markers of systemic inflammation predicted survival outcomes in advanced NSCLC.	28685599
Inflammation	Altered Intercellular Communication	Carriers of the risky genotype or haplotype also had increased gastric OPN expression (p = 0.038) and inflammation (p = 0.007).	28685609
Chronic lymphocytic inflammation, Pontine structure, Clippers	Altered Intercellular Communication	Introduction Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory central nervous system (CNS) disorder with particular involvement of the pons.	28685649
Inflammation, Amyloidosis	Altered Intercellular Communication	Systemic AA amyloidosis is a serious complication of chronic inflammation; however, there are relatively few published data on its incidence.	28686088
Communicable Diseases, Periodontitis, Inflammation	Altered Intercellular Communication	Infection and apoptosis associated with inflammation in periodontitis: An immunohistologic study.	28686335
Hypertrophy, Tubular atrophy, Interstitial Fibrosis Assessment, Interstitial inflammation	Altered Intercellular Communication	Histopathologically, glomerular enlargement, interstitial fibrosis, tubular atrophy, interstitial inflammation and global amyloid deposition were significantly associated with lower estimated glomerular filtration rate (eGFR) (p = .02, p < .001, p = .001, p = .009, p = .002, respectively) in univariate analysis.	28686525
Pain Distress Question, Arthritis, Inflammation, Neuralgia	Altered Intercellular Communication	The objectives were to quantify and characterize pain phenotypes (non-neuropathic vs. neuropathic features) among Danish arthritis patients using the PDQ, and to assess the association with on-going inflammation.	28686639
Pain Distress Question, Inflammation	Altered Intercellular Communication	PDQ-score was associated with DAS28-CRP and VAS pain but not with indicators of peripheral inflammation (CRP and SJC).	28686639
Inflammation	Altered Intercellular Communication	Coronary artery disease-associated genetic variants and biomarkers of inflammation.	28686695
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Genetic constitution and inflammation both contribute to development of coronary artery disease (CAD).	28686695
Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Petechiae, Purpura	Altered Intercellular Communication	Leukocytoclastic vasculitis (LCV) is a disease characterized by inflammation of small vessels presenting with petechiae and palpable purpura.	28686752
Inflammation, Noncommunicable Diseases	Altered Intercellular Communication	The association between total phthalate concentration and non-communicable diseases and chronic inflammation in South Australian urban dwelling men.	28686951
Inflammation, Noncommunicable Diseases	Altered Intercellular Communication	To investigate associations between urinary total phthalate concentration, chronic low-grade inflammation and non-communicable diseases in a cohort of South Australian men.	28686951
Inflammation, Chronic disease	Altered Intercellular Communication	Multivariable linear and logistic regression models were applied to determine associations of log-transformed urinary phthalate concentration with inflammation and chronic disease.	28686951
Inflammation, Chronic pain syndrome	Altered Intercellular Communication	Fibromyalgia, a potentially debilitating chronic pain syndrome of unknown etiology, may be characterized by inflammation.	28687081
Respiratory Distress Syndrome, Adult, Inflammation, Surfactant Dysfunction, Lung Volume Measurements, Respiration Disorders	Altered Intercellular Communication	We also provide expert consensus that mechanisms causing ARDS in adults and older children-namely complex surfactant dysfunction, lung tissue inflammation, loss of lung volume, increased shunt, and diffuse alveolar damage-are also present in several critical neonatal respiratory disorders.	28687343
Kidney Failure, Hypopituitarism	Altered Intercellular Communication	Failure of pituitary gland identification presented with hormonal insufficiency of 46.2%.	28687446
HIV Antigens, HIV Infections, Cardiovascular Diseases	Altered Intercellular Communication	To explore the link between HIV infection and cardiovascular diseases, we used postmortem human heart tissues obtained from HIV-infected and control uninfected individuals to examine connexin 43 (Cx43) expression and distribution and HIV-associated inflammation.	28688235
Cataract, Inflammation, Hypopyon	Altered Intercellular Communication	A 57-year-old female underwent cataract surgery and developed hypopyon on day 3 after surgery, with mainly anterior chamber inflammation.	28689242
Inflammation, Atherosclerosis	Altered Intercellular Communication	The high-WHtR group (>=0.5) showed greater morbidity and increased inflammation in association with atherosclerosis compared with the low-WHtR group.	28690284
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Vinpocetine Inhibits NF-kB-Dependent Inflammation in Acute Ischemic Stroke Patients.	28691141
Inflammation, Ischemic stroke	Altered Intercellular Communication	Immunity and inflammation play critical roles in the pathogenesis of acute ischemic stroke.	28691141
Inflammation	Altered Intercellular Communication	These effects led to significantly reduced secondary lesion enlargement and an attenuated inflammation reaction.	28691141
Inflammation, Ischemic stroke	Altered Intercellular Communication	These findings identify vinpocetine as an inflammation modulator that could improve clinical outcomes after acute ischemic stroke.	28691141
Inflammation, Ischemic stroke	Altered Intercellular Communication	This study also indicated the important role of immunity and inflammation in the pathogenesis of acute ischemic stroke and the significance of immunomodulatory treatment.	28691141
Inflammation, Irritation	Altered Intercellular Communication	Oral mucosa is constantly under the influence of various internal and external stimuli, therefore it is interested by a range of developmental disorders, irritation, inflammation, and neoplastic conditions.	28691450
Inflammation	Altered Intercellular Communication	It is argued that there are no modifiable factors such as age, or genetic factors, but that there are other factors that could be avoided, modified or controlled such as periodontal peripheral inflammation.	28691472
Inflammation	Altered Intercellular Communication	We conducted repeated measurements of lung function and inflammation biomarker in a cohort consisted of 60 participants with T2DM.	28692015
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Chronic inflammation and remodelling of the small airways are features related to chronic obstructive pulmonary disease (COPD).	28692348
Inflammation	Altered Intercellular Communication	Chronic HIV-1 infection leads to widespread inflammation and immune dysregulation.	28692540
Communicable Diseases, Inflammation	Altered Intercellular Communication	Both miRs de-repress the IL-6/STAT3 signaling pathway, which could contribute to increased inflammation during infection.	28692540
Inflammation	Altered Intercellular Communication	Cryopyrin-associated periodic syndromes (CAPS) result from gain-of-function mutations in the NLRP3 gene, which causes excessive release of interleukin-1b (IL-1b) and systemic inflammation.	28692792
Inflammation	Altered Intercellular Communication	Clinical presentation and CAPS markers of inflammation were captured.	28692792
Inflammation, Impaired cognition, Mental disorders	Altered Intercellular Communication	Elevated C-reactive protein (CRP), a non-specific biomarker of systemic bodily inflammation, has been associated with more pronounced cognitive impairments in adults with psychiatric disorders, particularly in the domains of memory and executive function.	28694011
Inflammation, Damage	Altered Intercellular Communication	Young age, complicated disease, and persistent inflammation were associated with bowel damage.	28694130
Inflammation, Dysplasia, Primary malignant neoplasm, Neoplasms, Adenocarcinoma of small intestine	Altered Intercellular Communication	Assessment of surgical specimens of small bowel adenocarcinomas revealed a clear transition from inflammation to dysplasia and cancer, whereas no tumors had evidence of microsatellite instability.	28694132
Adenocarcinoma, Adenocarcinoma of large intestine	Altered Intercellular Communication	Adenocarcinomas appeared to develop via an inflammation-dysplasia-carcinoma pathway, but differed from IBD-related colorectal adenocarcinomas in their molecular features.	28694132
Inflammation, pathologic fistula, With intensity	Altered Intercellular Communication	Among the 26 patients in clinical remission, 10 had persisting inflammation of fistulas on MRI (T2 hyperintensity, n = 7; contrast enhancement, n = 10).	28694669
ARCN1 gene, Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome, Chronic Obstructive Airway Disease, Inflammatory disorder, Asthma	Altered Intercellular Communication	A new phenotype with overlapping characteristics between asthma and chronic obstructive pulmonary disease (COPD) called asthma-COPD overlap syndrome (ACOS) is emerging among inflammation diseases.	28694694
Inflammation, Obesity, HIV Infections	Altered Intercellular Communication	We hypothesized inflammation increases when obesity and HIV infection co-occur.	28696344
Inflammation, Osteoporosis, Obesity	Altered Intercellular Communication	The excessive fat accumulation, local and systemic inflammation may lead to dysregulation in immune function and relevant health problems, including obesity and osteoporosis.	28696349
Inflammation	Altered Intercellular Communication	It results from synovial inflammation and direct cartilage-degenerating properties of blood components.	28696534
Inflammation, Hemarthrosis, Cartilage damage	Altered Intercellular Communication	In contrast, equimolar amounts of the fusion protein attenuated cartilage damage upon repeated joint bleeding, although synovial inflammation was hardly affected.	28696534
Inflammation, Non-alcoholic Fatty Liver Disease, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Type 2 diabetes patients with NAFLD had a higher prevalence of PAD, and this association was partly, but not entirely, explained by metabolic risk factors and inflammation.	28696562
Inflammation, Fatty degeneration	Altered Intercellular Communication	Increased key BAs were associated with higher grades of steatosis (taurocholate), lobular (glycocholate) and portal inflammation (taurolithocholate), and hepatocyte ballooning (taurocholate).	28696585
Airway structure, Asthma	Altered Intercellular Communication	Sputum eosinophil, being a marker of airway inflammation, can serve as a tool for assessing severity and response to treatment in asthma patients.	28696802
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Tissue inhibitor of metalloproteinase-1 (TIMP-1) is a protein implicated in the control of inflammation in a number of autoimmune diseases.	28696822
Neoplasms	Altered Intercellular Communication	Inflammation was the most common cause of false positives and small tumor volume and low 18F-FDG avidity were the causes of false negatives.	28697190
Fever, CTCAE	Altered Intercellular Communication	Six weeks later, the patient developed high fever again and in order to revaluate the periprosthetic inflammation, he was resubmitted to 18F-FDG PET/CT which showed normal 18F-FDG uptake in the whole skeleton, including the prosthesis and the subcutaneous wound.	28697197
Anxiety, CTCAE 3.0, Mood Disorders, Depression, CTCAE, Inflammation	Altered Intercellular Communication	Depression and anxiety are two common mood disorders that are both linked to systemic inflammation.	28697416
Inflammation, "Alzheimers Disease	Altered Intercellular Communication	The Relationship between Markers of Inflammation and Degeneration in the Central Nervous System and the Blood-Brain Barrier Impairment in Alzheimer's Disease.	28697565
Inflammation, Cerebral Hemorrhage	Altered Intercellular Communication	Although preclinical studies have shown inflammation to mediate perihematomal edema (PHE) after intracerebral hemorrhage, clinical data are lacking.	28698256
Inflammation, Pain Distress Question	Altered Intercellular Communication	Cold treatments are used to relieve joint inflammation and pain.	28698947
Bone Diseases, Inflammation, Chronic kidney disease mineral and bone disorder	Altered Intercellular Communication	Epidemiologic studies have suggested a link between chronic systemic inflammation and chronic kidney disease-mineral and bone disorder (CKD-MBD).	28699886
Chronic kidney disease mineral and bone disorder, Inflammation	Altered Intercellular Communication	Additionally, declining renal function is associated with worsening physical and cognitive function, which may potentially be explained by systemic inflammation, CKD-MBD, or both.	28699886
Chronic kidney disease mineral and bone disorder, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	We hypothesized that inhibiting inflammation with an interleukin-1 (IL-1) trap would improve markers of CKD-MBD as well as physical/cognitive function in patients with moderate-to-severe CKD.	28699886
Inflammatory Bowel Diseases, Inflammation, Anemia	Altered Intercellular Communication	We aimed to investigate the association of vitamin D status with inflammation, iron biomarkers, and anemia in pediatric IBD.	28700535
Inflammation, hepcidin, Anemia	Altered Intercellular Communication	Multivariable logistic/linear models were used to examine the associations of 25(OH)D with inflammation, iron status, hepcidin, and anemia.	28700535
Anemia	Altered Intercellular Communication	Iron deficiency prevalence (inflammation-corrected ferritin <15 mg/L or soluble transferrin receptor >8.3 mg/L) was 67%; anemia was 36%, and vitamin D insufficiency (25(OH)D <30 ng/mL) was 77%.	28700535
Inflammation, selenium, Ulcerative Colitis, Crohn Disease	Altered Intercellular Communication	In linear regression models, vitamin D insufficiency was associated with increased hepcidin levels (b [SE] = 0.6 [0.2], P = 0.01) and reduced hemoglobin (b [SE] = -0.9 [0.5], P = 0.046), controlling for age, sex, race, insurance status, body mass index for age, inflammation, disease diagnosis (ulcerative colitis versus Crohn's disease), and disease duration, compared with 25(OH)D >=30 ng/mL.	28700535
Inflammatory Bowel Diseases, Inflammation, Anemia	Altered Intercellular Communication	Further research is needed to clarify the association of vitamin D with inflammation, iron status, and anemia in pediatric IBD.	28700535
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Most ESRD patients have systemic inflammation, and increasing the risk of cardiovascular event.	28701158
Inflammation, Sarcopenia	Altered Intercellular Communication	The emergence of sarcopenia was accompanied by increased levels of inflammation factors TNF-a and IL-6.	28701179
Inflammation	Altered Intercellular Communication	Future studies should determine whether increasing life satisfaction and positive affect may contribute to improvements in health behaviors, inflammation, and better health outcomes.	28701268
Inflammation, destruction joint, Chronic arthritis	Altered Intercellular Communication	Synovial fibroblasts (SF) drive inflammation and joint destruction in chronic arthritis.	28701277
Inflammation, Fibrosis Assessment, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Extracellular accumulation of adenosine and subsequent activation of the ADORA2B receptor play important roles in regulating inflammation and fibrosis in IPF.	28701304
Inflammation, Demyelination, Degenerative brain disorder, CNS disorder	Altered Intercellular Communication	Multiple sclerosis (MS) is a pathologically complex CNS disease: inflammation, demyelination, and neuroaxonal degeneration occur concurrently and may depend on one another.	28702353
Gastroesophageal reflux disease, Chronic Obstructive Airway Disease, Gorontalo Language, Asthma	Altered Intercellular Communication	Gastroesophageal reflux disease (GORD) is well known to initiate or exacerbate pulmonary inflammatory conditions, inducing bronchial asthma and chronic obstructive lung disease.	28702854
Inflammation, Ulceration, CTCAE	Altered Intercellular Communication	Barium oesophagography, gastroesophageal endoscopy, and biopsy suggested oesophageal-related chronic inflammation and ulceration, which may have caused the repeated oesophagobronchial fistulas.	28703631
Obesity, Diabetes Mellitus	Altered Intercellular Communication	Association between Type 2 Diabetes, Obesity and Key Immunological Components of IgE-mediated Inflammation.	28704195
Immediate hypersensitivity, square decimeter, Obesity	Altered Intercellular Communication	The link between obesity and DM2 with immunological components of IgE-mediated allergic inflammation is not yet conclusively established.	28704195
Immediate hypersensitivity, square decimeter	Altered Intercellular Communication	To examine the key immunological components of IgE-mediated allergic inflammation in patients with DM2 and their relationship with glycemic control and anthropometric indicators.	28704195
Immediate hypersensitivity, square decimeter, Obesity	Altered Intercellular Communication	Obesity and poor glycemic control in patients with DM2 affect key immunological components of IgE-mediated allergic inflammation and possibly alter the immune response to allergens and antigens.	28704195
Inflammation, Metabolic Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Mitochondrial DNA (mtDNA) content might undergo significant changes caused by metabolic derangements, oxidative stress and inflammation that lead to development and progression of cardiovascular diseases.	28704533
Liver carcinoma, Hepatitis, Fibrosis Assessment, Inflammatory, Hepatobiliary Disorder, FAM126A gene, Carcinogenic Chlorinated Hydrocarbon, Liver Cirrhosis	Altered Intercellular Communication	Interferon-related genetic markers of necroinflammatory activity in chronic hepatitis C. Chronic hepatitis C (CHC) is a major cause of liver disease worldwide which often leads to progressive liver inflammation, fibrosis, cirrhosis and hepatocellular carcinoma (HCC).	28704535
Inflammation, Malnutrition	Altered Intercellular Communication	Multivariable adjustments were done for case-mix and markers of the malnutrition, and inflammation complex and intravenous iron dose.	28704813
Inflammation, Neoplasms, Esophageal carcinoma	Altered Intercellular Communication	Hamburg-Glasgow classification: preoperative staging by combination of disseminated tumour load and systemic inflammation in oesophageal carcinoma.	28704837
Inflammation, Neoplasms	Altered Intercellular Communication	Systemic inflammation and disseminated tumour load have a pivotal role in recurrence and oncological outcome.	28704837
Communicable Diseases, Inflammation	Altered Intercellular Communication	Infection and inflammation were associated with low levels of all long-chain (LC)-PUFAs, while hemoglobin was positively associated with whole-blood LC-PUFAs.	28705254
Communicable Diseases, Inflammation	Altered Intercellular Communication	Infection, inflammation, hemoglobin, anthropometry and diet were correlates of PUFAs concentrations in children with MAM.	28705254
Inflammation, East Frisian Low Saxon Language, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Chronic inflammation is an independent risk factor for cardiovascular disease (CVD), but most risk calculators, including the Framingham risk score (FRS) and the American College of Cardiology (ACC)/American Heart Association (AHA) risk score do not account for it.	28705378
Airway structure	Altered Intercellular Communication	Recent evidence has suggested that the innate immune response may play a role in the development of eosinophilic airway inflammation.	28705588
Airway structure	Altered Intercellular Communication	We previously reported that uric acid (UA) and adenosine triphosphate (ATP), two important damage-associated molecular pattern molecules (DAMPs), activate eosinophil functions, suggesting that these molecules may be involved in the development of eosinophilic airway inflammation.	28705588
Degenerative polyarthritis, Inflammation, Bone Marrow	Altered Intercellular Communication	Microarray analysis of bone marrow lesions in osteoarthritis demonstrates upregulation of genes implicated in osteochondral turnover, neurogenesis and inflammation.	28705915
Sarcoidosis	Altered Intercellular Communication	Genes comprising the composite gene expression score, TCR factor, may represent a blood-derived measure of T-cell activity and an indirect measure of active sarcoidosis inflammation.	28707108
Inflammation, Obesity	Altered Intercellular Communication	Immunosenescence Induced by Plasma from Individuals with Obesity Caused Cell Signaling Dysfunction and Inflammation.	28707376
Inflammation, Immunosenescence, Obesity	Altered Intercellular Communication	These results demonstrate that chronic systemic inflammation observed in obesity induces dysfunctional features in PBMC that are consistent with premature immunosenescence.	28707376
Inflammation	Altered Intercellular Communication	Histopathologic diagnosis revealed 42% (teeth = 8) without periapical inflammation, 16% (teeth = 3) with mild inflammation and 42% (teeth = 8) with moderate to intense inflammation.	28707526
Inflammation, Plasmodium falciparum infection	Altered Intercellular Communication	The prevalence of Plasmodium falciparum infection and inflammation during the study were 44-66%, and 57-76%, respectively.	28708072
Injury of cornea, Inflammatory abnormality of the eye	Altered Intercellular Communication	The double-masked phase demonstrated that CsA CE was effective in reducing corneal damage and ocular surface inflammation, and was well-tolerated over 6 months.	28708219
AATF wt Allele, Keratitis, Inflammatory abnormality of the eye	Altered Intercellular Communication	In this 12-month study, once-daily CsA CE was well-tolerated and showed reductions in ocular surface inflammation and improvements in signs/symptoms in DED patients with severe keratitis.	28708219
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	A local imbalance between regulatory (Treg) and effector T cells is believed to play a major role in gut-specific inflammation, including ulcerative colitis (UC).	28708802
Chronic Obstructive Airway Disease, asthma with copd	Altered Intercellular Communication	Neutrophilic inflammation is common in chronic obstructive pulmonary disease while Asthma COPD overlap syndrome has eosinophilic predominance.	28709489
ARCN1 gene, Inflammation, Asthma	Altered Intercellular Communication	Identifying the type of inflammation will aid in better management of COPD, but published studies show that induced sputum examination is more frequently used in asthma than COPD, with safety being the limiting factor.	28709489
Granulomatous inflammation, Cryptococcus	Altered Intercellular Communication	Diagnostic thoracoscopic wedge resection of the right lung nodule revealed granulomatous inflammation with cryptococcus on histopathology.	28709495
Inflammation, Atrophic	Altered Intercellular Communication	Atrophy (P = 0.001; P<0.01) and chronic inflammation grade (P = 0.026; P<0.05) were significantly higher in Staple Line Leak patients.	28709560
Refractory anemias, Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	ACS in RA has been linked to inflammation and RA severity.	28710095
Inflammation, Albuminuria, Cardiovascular morbidity	Altered Intercellular Communication	Albuminuria is a marker of inflammation and an independent predictor of cardiovascular morbidity and mortality.	28710178
Communicable Diseases, Inflammation, Pericardial Effusion, CTCAE, Pericarditis, Constrictive	Altered Intercellular Communication	Constrictive pericarditis secondary to endocardial pacemaker inflammation, without associated pericardial effusion or infection, has yet to be described in the literature.	28710300
Inflammation, Neoplasms	Altered Intercellular Communication	In conclusion, low serum APOA1 levels are associated with advanced stage and systemic inflammation, while serum APOB does not significantly correlate with tumor stage.	28710487
Inflammation, Thrombosis, palladium, Fibrosis Assessment, Cardiac complication	Altered Intercellular Communication	Aldosterone antagonist therapy and its relationship with inflammation, fibrosis, thrombosis, mineral-bone disorder and cardiovascular complications in peritoneal dialysis (PD) patients.	28710615
Degenerative polyarthritis, Inflammation, Synovial Fluid	Altered Intercellular Communication	Interestingly, OA affecting the synovial facet joint was associated with a marker of inflammation (HA).	28711584
Impaired cognition	Altered Intercellular Communication	Using a high-fat diet (HFD) consumption-induced obese mouse model, we tested our hypothesis that recombinant human FGF21 (rFGF21) administration is effective for improving obesity-induced cognitive dysfunction and anxiety-like behavior, by its multiple metabolic modulation and anti-pro-inflammation actions.	28712011
Hyperlipidemia, Impaired cognition, Hippocampus (Brain), Glucose Intolerance (disease), Neurogenesis	Altered Intercellular Communication	Our experimental findings support our hypothesis that rFGF21 is protective to HFD-induced cognitive impairment, at least in part by metabolic regulation in glucose tolerance impairment, insulin resistance, and hyperlipidemia; potent systemic pro-inflammation inhibition; and improvement of hippocampal dysfunction, particularly by inhibiting pro-neuroinflammation and neurogenesis deficit.	28712011
Inflammation, Eosinophilic esophagitis, Esophageal Diseases, "Extra-osseous Ewings sarcoma	Altered Intercellular Communication	Eosinophilic esophagitis (EoE) is a chronic, immune/antigen-mediated disease characterized by symptoms related to esophageal dysfunction and an eosinophil-predominant inflammation.	28712126
Pancreatic duct calculus, Pancreatitis	Altered Intercellular Communication	Acute pancreatitis is an inflammatory condition of pancreas, when, associated with pancreatic duct stones a lateral pancreaticojejunostomy is done, which, results in better outcomes decreasing the mortality and morbidity.	28712198
Inflammation, Non-Small Cell Lung Carcinoma, Depression, CTCAE	Altered Intercellular Communication	Depression, inflammation, and epidermal growth factor receptor (EGFR) status in metastatic non-small cell lung cancer: A pilot study.	28712427
Inflammation, Thrombocytosis, Atherosclerosis	Altered Intercellular Communication	Thrombocytosis and inflammation are vital elements in the pathogenesis of atherosclerosis.	28712557
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	After two failed bevacizumab intravitreal injections, uveitis responded to systemic adalimumab administration, with a complete and long-term remission of ocular inflammation.	28713058
Inflammation, Inflammatory disease of mucous membrane	Altered Intercellular Communication	CCE-2 had a sensitivity of 97% and 94% to detect mucosal inflammation (MES >0) and moderate to severe inflammation (MES >1), respectively.	28713062
Inflammation, Hemorrhage, Superficial ulcer	Altered Intercellular Communication	In per-segment analysis, the negative predictive values of CCE-2 to detect mucosal inflammation, including vascular pattern loss, bleeding, and erosions reached 94% to 95%.	28713062
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Chronic disease	Altered Intercellular Communication	Type 2 diabetes (T2D) is an age-related chronic disease associated with metabolic dysregulation, chronic inflammation, and activation of peripheral blood mononuclear cells (PBMC).	28713486
Communicable Diseases, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Infection and inflammation were associated with mortality in individuals both with and without diabetes.	28713837
Temporomandibular Joint Disorders, Inflammation, Synovitis	Altered Intercellular Communication	TMD is frequently associated with synovitis, a chronic inflammation of the synovium.	28714016
Inflammation	Altered Intercellular Communication	These findings suggest a model for inflammation in the TMJ where EDPs are generated by harmful mechanical stimuli, induce both a pro-inflammatory cascade and increase expression of MMP-12 through activation of the EBP signalling cascade.	28714016
Inflammation	Altered Intercellular Communication	This may lead to further increases in EDP levels, establishing a positive feedback loop leading to chronic inflammation in the TMJ.	28714016
palladium, Inflammation, HD Term Type, Atherosclerosis	Altered Intercellular Communication	We evaluated the association between residual renal function (RRF), phosphate level, inflammation and other risk factors in carotid modeling as a marker of early atherosclerosis in peritoneal dialysis (PD) compared with hemodialysis (HD) patients.	28714271
Inflammation, Arthritis	Altered Intercellular Communication	While the cytokine and cellular pathways triggering arthritis are well defined, those responsible for the resolution of inflammation are incompletely characterized.	28714991
Inflammation	Altered Intercellular Communication	Here we identified interleukin (IL)-9-producing type 2 innate lymphoid cells (ILC2s) as the mediators of a molecular and cellular pathway that orchestrates the resolution of chronic inflammation.	28714991
Inflammation	Altered Intercellular Communication	Hence, fostering IL-9-mediated ILC2 activation may offer a novel therapeutic approach inducing resolution of inflammation rather than suppression of inflammatory responses.	28714991
Inflammation	Altered Intercellular Communication	Following each surgery, the emphasis was on decreasing inflammation and maintaining patellar mobility while increasing joint range of motion and strength.	28715241
Inflammation, Anxiety Disorders, Bipolar Disorder	Altered Intercellular Communication	T. gondii seropositivity is associated with generalized anxiety disorder, depressive symptoms and comorbid depressive and anxiety disorders, which is not mediated by inflammation.	28715724
Inflammation, Autoimmune Diseases, Fibrosis Assessment, Sample Size Calculation, Abnormality of the vasculature	Altered Intercellular Communication	Systemic sclerosis (SSc) is an autoimmune disease characterized by microvascular abnormalities, inflammation and fibrosis.	28716007
Hormone abnormality, Alopecia	Altered Intercellular Communication	Distribution of hair loss and associated hormonal abnormalities aid in the recognition of FFA in men.	28716436
Compression injury of nerve, Optic Neuritis	Altered Intercellular Communication	Two main hypotheses have been proposed for the pathophysiology of long thoracic nerve (LTN) palsy: nerve compression and nerve inflammation.	28716694
Inflammation, Neoplasms	Altered Intercellular Communication	Per-operative freeze-microscopy showed inflammation tissue, whereas subsequent microscopy showed papillary-cystic endolymphatic sac tumor.	28716765
Inflammation, Takayasu Arteritis, Aortitis, Arteritis	Altered Intercellular Communication	There are a few published cases of diffuse aortitis and aorta collaterals inflammation that fulfill Takayasu's arteritis (TA) criteria coexisting with AS.	28718336
Refractory Cytopenia of Childhood, Inflammation, Renal Cell Carcinoma Pathway	Altered Intercellular Communication	The relation between diet-related inflammation and renal cell carcinoma (RCC) has not been investigated.	28718670
Inflammation, Demyelination	Altered Intercellular Communication	The extent and distribution of fibrin(ogen) was assessed and related to measures of demyelination, inflammation, and neuronal density.	28719020
Presenile dementia, Inflammation, Primary malignant neoplasm, Immune System Diseases	Altered Intercellular Communication	Although chronic inflammation and immune disorders are of great importance to the pathogenesis of both dementia and cancer, the pathophysiological mechanisms are not clearly understood.	28719625
Inflammation, Obesity	Altered Intercellular Communication	Thus, results of this study indicate that WHtR is a simple and effective anthropometric variable that has the potential to identify central obesity and the associated inflammation even in women with normal BMI.	28719789
Alzheimers Disease", Inflammation, Data types - Address	Altered Intercellular Communication	In Alzheimer disease (AD) inflammation becomes evident throughout the course of the disease.	28719891
Inflammation, Impaired cognition	Altered Intercellular Communication	However, the association between inflammation, cognitive impairment, and cerebrospinal biomarkers (Ab42, t-tau, p-tau181, and Ab42/p-tau181 ratio) is poorly understood.	28719891
Inflammation, Opisthorchis viverrini Infection, Cholangiocarcinoma, Fibrosis Assessment, FBN2 wt Allele	Altered Intercellular Communication	Opisthorchis viverrini infection induces chronic inflammation, and a minor proportion of infected individuals develop advanced periductal fibrosis (APF) and cholangiocarcinoma (CCA).	28719954
Down Syndrome, "Alzheimers Disease", Inflammation Mediators, Data types - Address	Altered Intercellular Communication	We hypothesized that an inflammation-mediated dysregulation of these miRNAs may occur in patients with Down syndrome (DS) and Alzheimer's disease (AD).	28720071
Neoplasms	Altered Intercellular Communication	These symptoms may occur because of changes in neurotransmitter secretion caused by tumors.	28720269
Aneurysm, Rupture	Altered Intercellular Communication	Aortic Wall Inflammation Predicts Abdominal Aortic Aneurysm Expansion, Rupture, and Need for Surgical Repair.	28720724
Inflammation, Aortic Aneurysm, Abdominal, Aneurysm	Altered Intercellular Communication	USPIO-enhanced MRI is a novel approach to the identification of aortic wall cellular inflammation in patients with abdominal aortic aneurysms and predicts the rate of aneurysm growth and clinical outcome.	28720724
Inflammation, Ischemic stroke	Altered Intercellular Communication	Increased monocyte count associated with HARM supports importance of systemic inflammation in BBB disruption in acute ischemic stroke.	28722240
Inferior vena cava structure, Inflammation, Thrombosis, Compression	Altered Intercellular Communication	Hepatic vein and inferior vena cava (IVC) thrombosis are rare but well-documented complications of ALA, typically attributed to mechanical compression and inflammation associated with a large abscess.	28722597
Inflammation, Dysplasia, Gastritis, Malignant Neoplasms, Goblet Cells	Altered Intercellular Communication	Moderate chronic gastritis with lymphoid aggregates and slight acute inflammation were noticed, whereas no malignancy, dysplasia, or goblet cell metaplasia was detected.	28723278
Weight Gain, Inflammation	Altered Intercellular Communication	NF-kB p65 serine 467 phosphorylation sensitizes mice to weight gain and TNFa-or diet-induced inflammation.	28723419
Hepatitis	Altered Intercellular Communication	Although glucose metabolism or insulin sensitivity was not improved, diet-induced liver inflammation was diminished in S467A mice.	28723419
Sarcoidosis, Tuberculosis	Altered Intercellular Communication	However, F-18 FDG can also exhibit intense accumulation in tissues in inflammatory conditions such as active tuberculosis (TB) and sarcoidosis.	28723740
Inflammation	Altered Intercellular Communication	An obstructed chest tube, leaving unevacuated blood around the heart and lungs, can lead to atrial inflammation, which can trigger POAF.	28724233
Osteomyelitis, Granulomatous inflammation, Vasculitis, CTCAE, Pseudomonas aeruginosa	Altered Intercellular Communication	Biopsy of the skull base/clivus revealed necrotising granulomatous inflammation with focal vasculitis consistent with GPA, and multiple bone cultures were positive for Pseudomonas aeruginosa This patient was diagnosed concurrently with GPA and P. aeruginosa skull base osteomyelitis.	28724596
Cessation of life, Inflammation, Calcinosis	Altered Intercellular Communication	A minority of veins expressed markers of inflammation, cell proliferation, cell death, calcification, or neoangiogenesis.	28724774
Sepsis, Inflammation	Altered Intercellular Communication	These findings demonstrate that anti-HMGB1 antibodies alter inflammation in murine sepsis models and reduce sepsis mortality without potentiating immunosuppression.	28724977
Inflammation, Gastritis, Bacterial Infections, Malignant neoplasm of stomach	Altered Intercellular Communication	Helicobacter pylori is responsible for 70% of gastric cancers globally, and patients with this bacterial infection often present with early stages of the carcinogenic pathway such as inflammation or gastritis.	28725964
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Other studies have shown the relationship between high vagus nerve activity and survival in cancer patients via reduced levels of inflammation, indicating the essential role of the vagus nerve.	28726018
Diabetic Nephropathy, Inflammation, Metabolic Diseases, Diabetes Mellitus	Altered Intercellular Communication	Diabetic nephropathy (DN) is one of the most lethal complications of diabetes mellitus with metabolic disorders and chronic inflammation.	28726774
Diabetic Retinopathy, Cardiac complication, Inflammation, GDC Disease Response Terminology	Altered Intercellular Communication	Diabetic retinopathy (DR) is a well-known microvascular complication related to inflammation.	28726778
Inflammation	Altered Intercellular Communication	FOXQ1 regulates senescence-associated inflammation via activation of SIRT1 expression.	28726780
Inflammation, Frontal fibrosing alopecia	Altered Intercellular Communication	Thermal imaging and dermoscopy for detecting inflammation in frontal fibrosing alopecia.	28727235
Frontal fibrosing alopecia, Nonesterified Fatty Acids	Altered Intercellular Communication	Frontal fibrosing alopecia (FFA) is an inflammatory condition of the scalp, which leads to scarring and slowly progressive recession of frontotemporal and/or frontoparietal hairline.	28727235
Herpes zoster disease, Hertz (Hz), Postherpetic neuralgia, Inflammation	Altered Intercellular Communication	Herpes zoster (HZ) is associated with inflammation of the peripheral nerves, which is considered to be an important cause of postherpetic neuralgia (PHN).	28727702
Inflammation, Chronic sinusitis, Craniosynostosis, Inflammatory disorder	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) is a common inflammatory disorder of the upper airway characterized by chronic inflammation and significant sinonasal remodeling.	28727907
Inflammation, Cystitis	Altered Intercellular Communication	Xanthogranulomatous cystitis (XC) is a rare condition affecting the bladder thought to be caused by chronic inflammation.	28727973
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Clinical evidence increasingly suggests inflammation may be important specifically for an etiologically distinct depression subtype, characterised by resistance to antidepressant medication.	28728805
Inflammation, Depression, CTCAE, Psychological Distress	Altered Intercellular Communication	However, epidemiological investigations of the relationship of inflammation with depression and psychological distress have failed to acknowledge these developments, which may have resulted in bias or masking of associations driven by the subtype.	28728805
Inflammatory, Inflammation	Altered Intercellular Communication	An antidepressant-resistant, inflammatory depression subtype would result in stronger associations of depressive symptomatology with inflammation among antidepressant users than non-users, due to over-representation of subtype individuals among antidepressant users experiencing severe or persistent symptoms.	28728805
Inflammation, COL4A2 wt Allele	Altered Intercellular Communication	MIF in serum might be a potential biomarker for reflecting inflammation, severity and prognosis of ICH patients.	28729134
Inflammation, Adenocarcinoma of large intestine	Altered Intercellular Communication	Implications of inflammation and remodeling of the enteric glial cells in colorectal adenocarcinoma.	28730232
Chronic dacryocystitis, Inflammation	Altered Intercellular Communication	Chronic dacryocystitis (CD) is an inflammation of the lacrimal sac and nasolacrimal duct with a long-standing evolution.	28730240
Chronic lymphocytic inflammation	Altered Intercellular Communication	The sac wall revealed chronic diffusion (88.88%) or nodular lymphocytic inflammation (11.11%).	28730240
Inflammation	Altered Intercellular Communication	Applying CIS system, the majority of cases (13 patients, 72.22%) were identified with moderate chronic inflammation, only one case (5.55%) pointed out a mild degree of inflammation with a CIS<3, but four (22.22%) cases showed severe inflammatory changes with a CIS>6.	28730240
Inflammation, Asthma, Airway Obstruction	Altered Intercellular Communication	Lung sound analysis (LSA) has been reported to be useful for predicting airway obstruction and inflammation in patients with bronchial asthma.	28731412
palladium, Inflammation	Altered Intercellular Communication	Lastly, we identified increased expression of the neurodegenerative marker S100B, but not CRP, in PD and MSA patients, indicating local rather than systemic inflammation.	28732710
Inflammation, COL4A2 wt Allele, Cerebral Hemorrhage	Altered Intercellular Communication	Inflammation may determine the prognosis of intracerebral hemorrhage (ICH), which has high mortality and morbidity rates.	28733122
Bronchiectasis	Altered Intercellular Communication	Effects of an Airway Clearance Device on Inflammation, Bacteriology, and Mucus Transport in Bronchiectasis.	28733314
Inflammation, Bronchiectasis	Altered Intercellular Communication	Bronchiectasis is characterized by abnormal and permanent dilation of the bronchi, caused by the perpetuation of inflammation and impairment of mucociliary clearance.	28733314
Inflammation, Bronchiectasis, Cardiac Flutter	Altered Intercellular Communication	We evaluated the effects of the flutter valve on sputum inflammation, microbiology, and transport of respiratory secretions in patients with bronchiectasis.	28733314
Inflammation	Altered Intercellular Communication	To test two interventions to reduce interleukin (IL)-6 levels, an indicator of low-grade chronic inflammation and an independent risk factor for impaired mobility and slow walking speed in older adults.	28734043
Inflammation	Altered Intercellular Communication	The ENRGISE Pilot Study will inform a larger subsequent trial that is expected to have important clinical and public health implications for the growing population of older adults with low-grade chronic inflammation and mobility limitations.	28734043
Inflammation, Asthma	Altered Intercellular Communication	Toll-like receptor 3, an innate pattern recognition receptor, is triggered by HRV, driving inflammation that can worsen asthma.	28734844
Nonalcoholic Steatohepatitis, Inflammation, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Fatty Liver Disease	Altered Intercellular Communication	NAFLD comprises the spectrum from simple steatosis (nonalcoholic fatty liver, NAFL), to steatosis with inflammation (nonalcoholic steatohepatitis, NASH).	28735109
Inflammation, Electrocardiogram: myocardial infarction (finding), Atherosclerosis	Altered Intercellular Communication	The biphasic inflammation after ST-segment elevation myocardial infarction (STEMI) plays an important role in myocardial healing and progression of systemic atherosclerosis.	28735289
Inflammation, Fever, CTCAE	Altered Intercellular Communication	Fever during the second phase but not the first phase of post-STEMI inflammation was a strong associated factor with worse long-term cardiac outcomes in patients after STEMI, suggesting the need to consider the optimal timing for anti-inflammatory strategies after STEMI.	28735289
Intraocular inflammation, Corneal Opacity	Altered Intercellular Communication	No corneal opacity or intraocular inflammation was observed after topical steroid treatment for one month.	28736046
Inflammation	Altered Intercellular Communication	u-ORM measurements might provide a novel non-invasive tool for real-time monitoring of systemic inflammation, however further investigations are required to confirm it.	28736055
Inflammation, Diabetic foot ulcer	Altered Intercellular Communication	Potential of circulatory procalcitonin as a biomarker reflecting inflammation among South Indian diabetic foot ulcers.	28736121
Weight Gain, Steatohepatitis, Inflammation	Altered Intercellular Communication	DBZ protects against HFD-induced body weight gain, insulin resistance, hepatic steatosis and inflammation in mice.	28736228
Inflammation	Altered Intercellular Communication	Cobalt-treated monocytes/macrophages effectively supported Th17 inflammation, by an IL-6-dependent but not TNF-dependent mechanism.	28736908
Pain Distress Question, Inflammation, Diabetic Ketoacidosis, Nephrolithiasis	Altered Intercellular Communication	Nephrolithiasis can increase insulin resistance due to increased pain and inflammation, so these patients should be monitored closely for recurrence of DKA.	28737266
Inflammation, Hemolysis (biological function)	Altered Intercellular Communication	BackgroundProlonged storage of transfused red blood cells (RBCs) is associated with hemolysis in healthy adults and inflammation in animal models.	28738026
Inflammation, Mental disorders, GDC Comorbidity Terminology	Altered Intercellular Communication	To the extent that many psychiatric disorders are comorbid with or causally related to stress and inflammation, decreased neurogenesis could be a partial contributor to the pathophysiology of the disorders.	28738394
Drug abuse, Inflammation, Psychiatric	Altered Intercellular Communication	Therefore, it is not clear whether changes in neurogenesis that occur alongside psychiatric illnesses are a cause or a consequence of the mediating factors such as stress, drug abuse, and inflammation, which are complexly involved in the disorders.	28738394
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Elevated microRNA-125b promotes inflammation in rheumatoid arthritis by activation of NF-kB pathway.	28738524
Refractory anemias, Inflammation	Altered Intercellular Communication	In conclusion, our results suggest that elevated miR-125b promotes inflammation in RA by activation of NF-kB pathway.	28738524
Inflammation, Atherosclerosis	Altered Intercellular Communication	Low-grade inflammation, represented by minor C-reactive protein (CRP) elevation, has a critical role in the early stages of atherosclerosis, and pantothenic acid (PA) may have an antioxidant effect in inflammatory process.	28739188
Inflammation, Choroidal Neovascularization	Altered Intercellular Communication	Inflammation has been strongly implicated in the pathogenesis of choroidal neovascularization.	28739342
Inflammation, Choroidal Neovascularization	Altered Intercellular Communication	Our data illustrate a functional role for TLR2 in the pathogenesis of choroidal neovascularization, likely by promoting inflammation of the retinal pigment epithelium, and validate TLR2 as a novel therapeutic target for reducing choroidal neovascularization.	28739342
Autoimmune Diseases, Inflammation, polychondritis	Altered Intercellular Communication	Relapsing polychondritis is a very rare autoimmune disease characterised by a relapsing inflammation of hyaline, elastic and fibrous cartilaginous tissues.	28739564
Inflammation, polychondritis, Polyarthritis	Altered Intercellular Communication	We report an elderly man who presented with recurrent bilateral ear inflammation and intermittent polyarthritis who was diagnosed with relapsing polychondritis with asymptomatic involvement of his large airways.	28739564
Pituitary Gland	Altered Intercellular Communication	Radiological evidence of pituitary inflammation was detected only in one case.	28739711
Arterial Stiffness, Inflammation	Altered Intercellular Communication	Relation between Arterial Stiffness and Markers of Inflammation and Hemostasis - Data from the Population-based Gutenberg Health Study.	28740206
Arterial Stiffness, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	The relation between inflammation, hemostasis and arterial stiffness is of pathophysiological relevance for the development of cardiovascular disease (CVD).	28740206
Arterial Stiffness, Inflammation	Altered Intercellular Communication	The results support the relation between inflammation, hemostasis and arterial stiffness measured by digital photoplethysmography.	28740206
Inflammation	Altered Intercellular Communication	Markers of inflammation and hemostasis modulate the ability of SI to identify subjects at risk for future CVD or higher mortality.	28740206
Inflammatory Bowel Diseases, Colitis	Altered Intercellular Communication	Decrease in genus Phascolarctobacterium was linked to presence of colonic inflammation regardless of IBD phenotype.	28740343
Pain Distress Question, Inflammation	Altered Intercellular Communication	Each participant was genotyped for 4392 single nucleotide polymorphisms in genes implicated in pain perception, inflammation and mood and tested for association with pain sensitivity.	28741447
Inflammation, Neoplasms	Altered Intercellular Communication	Lipids are known to influence tumour growth, inflammation and chemoresistance.	28741687
Inflammation, Arteriosclerosis, Sarcopenia	Altered Intercellular Communication	Sarcopenia and physical function are associated with inflammation and arteriosclerosis in community-dwelling people: The Yakumo study.	28741974
Inflammation, Arteriosclerosis, Skeletal muscle structure, Sarcopenia	Altered Intercellular Communication	Sarcopenia reduces physical function, while chronic inflammation causes arteriosclerosis and decreases skeletal muscle.	28741974
Inflammation, Arteriosclerosis, Sarcopenia	Altered Intercellular Communication	We conducted a cross-sectional study to elucidate the associations among sarcopenia, physical function, arteriosclerosis, and inflammation in community-dwelling people.	28741974
Inflammation, Arteriosclerosis, Sarcopenia	Altered Intercellular Communication	These findings indicate that chronic inflammation may relate arteriosclerosis and sarcopenia simultaneously.	28741974
methyldopa, Inflammation, Neurodegenerative Disorders	Altered Intercellular Communication	Increasing evidence demonstrates that inflammation and endoplasmic reticulum (ER) stress is implicated in the development and progression of age-related macular degeneration (AMD), a multifactorial neurodegenerative disease.	28742151
methyldopa, Inflammation	Altered Intercellular Communication	The present study investigates a possible intersection between ER stress and inflammation in AMD.	28742151
Amyotrophic Lateral Sclerosis, Inflammation	Altered Intercellular Communication	We identified 32 leukocyte phenotypes that were altered in ALS patients compared to age and gender matched healthy volunteers (HV) that included phenotypes of both inflammation and immune suppression.	28742871
Inflammation, Atherosclerosis	Altered Intercellular Communication	Peripheral leucocytes and tissue gene expression of granzyme B/perforin system and serpinB9: Impact on inflammation and insulin resistance in coronary atherosclerosis.	28743062
Inflammation, Atherosclerosis	Altered Intercellular Communication	GZB and PI-9 could be effective modulators for inflammation and insulin resistance in atherosclerosis.	28743062
Inflammation	Altered Intercellular Communication	As the disease progresses, the active inflammation of large vessels leads to dilation, narrowing and occlusion of the arteries.	28743241
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	A novel systematic inflammation related index is prognostic in curatively resected non-metastatic colorectal cancer.	28743381
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	IPI is readily available, independently prognostic and may reflect the host inflammation, immune and nutritional status that could have impact on cancer progression.	28743381
ARCN1 gene, Inflammation	Altered Intercellular Communication	Oxidative stress and systemic inflammation are higher in smokers and patients with COPD; however, markers that may help differentiate between smokers and patients with COPD have not yet been identified.	28744116
ARCN1 gene, Inflammation	Altered Intercellular Communication	Although smokers and patients with early COPD presented other increased systemic inflammation markers (eg, CRP) and oxidative stress (measured by AGEs), they did not differentiate smokers from COPD.	28744116
Muscle damage, Inflammation, Muscle Fatigue	Altered Intercellular Communication	The practice of prolonged exercise with high intensity, as seen in triathlon training, can cause physiological imbalances that might result in muscle fatigue, muscle damage and changes in systemic inflammatory response, thus reduce the athletes' physical performance, therefore, both adequate total caloric and macronutrient intake also the use of a specific ergogenic aid, as taurine supplementation would be an alternative to prevent inflammation and muscle damage.	28745470
Cessation of life, Inflammation, Amyloidosis, Kidney Failure	Altered Intercellular Communication	AA amyloidosis is a serious complication of persistent inflammation, which, untreated will progress to renal failure and death.	28745926
Inflammation	Altered Intercellular Communication	A heparin-surface-modified IOL may reduce the incidence of recurrent inflammation.	28746181
Autoimmune Diseases, Inflammation, AAVS1 gene, Vasculitis, CTCAE	Altered Intercellular Communication	Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of autoimmune diseases characterized by systemic inflammation in small- to medium-sized blood vessels.	28746217
Schistosomiasis, Anemia, Congenital Abnormality	Altered Intercellular Communication	Schistosomiasis is a parasite-related chronic inflammatory condition that can cause anemia, decreased growth, liver abnormalities, and deficits in cognitive functioning among children.	28746403
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Leucine-rich a2-glycoprotein-1 (LRG1) is overexpressed during inflammation and is associated with various malignancies.	28746773
Inflammation, Anemia	Altered Intercellular Communication	Identically, in the subgroup of 76 patients with no inflammation (CRP <5 mg/L) and no iron deficiency (TSAT >20%) linear regression between IAA, IS or PCS and any anemia parameter did not reach significance.	28747155
Acute Kidney Injury, CTCAE, Acute Coronary Syndrome, Inflammation	Altered Intercellular Communication	Acute coronary syndrome and acute kidney injury: role of inflammation in worsening renal function.	28747177
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation and its components play an important role in the worsening of renal function in ACS.	28747177
Pain Distress Question, Inflammation	Altered Intercellular Communication	Associations were maintained in fully adjusted models of intrusive body pain and difficulty climbing stairs, but for chair rise speed they were fully accounted for by inflammation, body-size and lifestyle.	28747665
Giant Cell Arteritis, Inflammation, GCA gene, Musculoskeletal Pain	Altered Intercellular Communication	Monocytes/macrophages are critical in systemic and local inflammation in giant cell arteritis (GCA) and possibly in clinically overlapping polymyalgia rheumatica (PMR).	28747747
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Involvement of the leptin-adiponectin axis in inflammation and oxidative stress in the metabolic syndrome.	28747790
Inflammation, Metabolic Syndrome X, MS gene	Altered Intercellular Communication	The aim of the present work was to study whether the leptin-adiponectin axis may have a pathophysiological role in the increased systemic inflammation and oxidative stress observed in patients with the metabolic syndrome (MS).	28747790
Inflammation	Altered Intercellular Communication	We concluded that a dysfunctional adipose tissue as suggested by a low adiponectin/leptin ratio may contribute to the increased oxidative stress and inflammation, hallmarks of the MS.	28747790
Granulomatosis, Orofacial, Inflammation	Altered Intercellular Communication	Orofacial granulomatosis (OFG) is the term given to a group of diseases characterized by the presence of non-necrotizing granulomatous inflammation affecting the soft tissues of the orofacial region.	28748609
Inflammation, Obesity	Altered Intercellular Communication	suPAR may be a good novel biomarker for systemic subclinical inflammation and immune activation linked to adolescent obesity.	28749394
Airway structure, Signs and Symptoms, Respiratory	Altered Intercellular Communication	The study provides evidence that airway inflammation and the frequency of respiratory symptoms increase, whereas lung function decreases with increased ozone exposure in schoolchildren.	28749779
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Signal intensity on T2WI images was used to distinguish between inflammation and fibrosis.	28750685
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	ORN of the hyoid bone were detected in 30% of patients after treatment, with 23% of them showing inflammation and 7.7% fibrosis.	28750685
Stable chronic Graft vs Host Disease, Inflammation	Altered Intercellular Communication	These results identify dual TCR cells as specific mediators of pathogenic inflammation underlying cGVHD and highlight Tbet-driven T cell function as a potential pathway for potential therapeutic targeting.	28750779
Inflammation, Lupus Nephritis, Vasculitis, CTCAE, Necrosis	Altered Intercellular Communication	Class IV-S lupus nephritis is often associated with more necrosis and fewer subendothelial immune deposits compared to class IV-G lupus nephritis, suggestive of necrotising glomerular inflammation found in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis.	28750930
Inflammation, Dentigerous Cyst	Altered Intercellular Communication	Significant association of high-grade inflammation and thick lining epithelium with the increased number of Langerhans cells in dentigerous cysts.	28751089
Inflammation	Altered Intercellular Communication	A significant association of high-grade inflammation and thick lining epithelium with the increased LC number in DCs is found.	28751089
Pancreatitis, Epigastric pain	Altered Intercellular Communication	BACKGROUND Acute pancreatitis is an inflammatory condition of the pancreas characterized clinically by epigastric abdominal pain and elevated levels of pancreatic enzymes in the blood.	28751631
Calcinosis	Altered Intercellular Communication	Vitamin D seems an intriguing molecule to explore in the field of AAD since it improves endothelial function and protects smooth muscle cells from inflammation-induced remodeling, calcification, and loss of function, all events which are strongly related to the aging process.	28751822
Dyspnea, Wheezing	Altered Intercellular Communication	The patient presented with stubborn dyspnea and wheezing although received integrated treatment, including anti-infection, anti-inflammation, and intravenous immunoglobulin.	28752681
Inflammation, Acantholysis	Altered Intercellular Communication	PD-1 inhibitor-associated lichenoid inflammation with incidental suprabasilar acantholysis or vesiculation-Report of 4 cases.	28753231
Inflammation, Spongiosis	Altered Intercellular Communication	In 2 patients, the clefts were well developed and had some acantholytic cells while the other 2 appeared to be spongiosis or inflammation related.	28753231
Inflammation, Hypothyroidism, Hashimoto Disease, Autoimmune Thyroid Disease Pathway, Haiti, Vitamin D measurement	Altered Intercellular Communication	Hashimoto's thyroiditis (HT), the most frequent autoimmune thyroid disease (AITD), is characterized by chronic inflammation of the thyroid gland that usually results in hypothyroidism.	28753406
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Associations between self-reported diabetes and 78 circulating markers of inflammation, immunity, and metabolism among adults in the United States.	28753646
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Inflammation is increasingly thought to be associated with diabetes; however, only a few inflammation markers have been assessed concurrently in relation to history of diabetes.	28753646
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	These results highlight the need to explore in future prospective studies the role of inflammation markers in diabetes.	28753646
Inflammation	Altered Intercellular Communication	Nonsteroidal anti-inflammatory drugs (NSAIDs) reduce inflammation and also PSA elevations due to intraprostatic inflammation.	28753870
Inflammation, Malignant Neoplasms, Dysbiosis	Altered Intercellular Communication	The pathogenesis of gut inflammation, bacterial dysbiosis and increased rates of malignancy in CF is unclear.	28754328
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Fecal M2-pyruvate kinase (M2-PK) is a biomarker indicative of cellular proliferation that may be raised in intestinal malignancy and inflammation.	28754328
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	We also determined whether this relationship was independent of coronary artery disease (CAD) and hs-CRP, a marker of systemic inflammation.	28754439
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	This effect is independent of the presence of coronary artery disease and also systemic inflammation.	28754439
Inflammation, Prostate carcinoma	Altered Intercellular Communication	A Prospective Study of Chronic Inflammation in Benign Prostate Tissue and Risk of Prostate Cancer: Linked PCPT and SELECT Cohorts.	28754796
Diabetic Retinopathy, Inflammation	Altered Intercellular Communication	Diabetic retinal maculopathy is associated with acute and chronic local inflammation.	28755024
Inflammation	Altered Intercellular Communication	Acute phase factors may contribute to local inflammation in DME and may therefore influence disease progression.	28755024
Inflammation, Fibrosis Assessment, Secondary malignant neoplasm of liver, Colorectal Carcinoma	Altered Intercellular Communication	The hepatic microenvironment, which may include chronic inflammation and fibrosis, is considered to contribute to the pathogenesis of liver metastases of colorectal cancer.	28755421
Inflammation, Jaw Keratocyst	Altered Intercellular Communication	Significant association of inflammation grade with the number of Langerhans cells in odontogenic keratocysts.	28755796
Inflammation	Altered Intercellular Communication	The mean LC counts in the lining epithelia and subepithelial connective tissues increased significantly from no inflammation (0.5 +- 0.4 and 0.7 +- 0.6 cell/high-power field or HPF, respectively) through mild/moderate inflammation (5.9 +- 2.7 and 5.0 +- 3.5 cells/HPF, respectively) to severe inflammation OKC sites (14.7 +- 5.3 and 13.3 +- 6.8 cells/HPF, respectively; all P-values < 0.001).	28755796
Inflammation	Altered Intercellular Communication	OKC sites with inflammation had thicker lining epithelia than those without inflammation.	28755796
Inflammation	Altered Intercellular Communication	A significant association of inflammation grade with the number of LCs in OKCs is found.	28755796
Inflammation, Aggressive behavior	Altered Intercellular Communication	The paucity of finding LCs in the lining epithelia of OKCs without inflammation indicates the loss of immunosurveillance ability against the OKC lining epithelial cells; this can explain why OKCs have aggressive clinical behavior, a great growth potential, and a high recurrence rate.	28755796
Inflammation, Malnutrition, Myocardial	Altered Intercellular Communication	Low total T3 levels are common in dialysis patients and are associated with inflammation, malnutrition and myocardial damage.	28755902
Primary sclerosing cholangitis, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis Frequently Have Subclinical Inflammation in the Proximal Colon.	28756053
Inflammation, Neoplasms, Ulcerative Colitis	Altered Intercellular Communication	Histologic inflammation is an independent risk factor for the development of neoplasia; we investigated whether patients with UC and PSC have more subclinical disease activity than patients with UC alone.	28756053
Discordance, Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In each colonic segment, differences in disease activity and the degree of discordance between endoscopic and histologic inflammation among UC patients with and without PSC were compared.	28756053
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Patients with UC and PSC who are in clinical remission are significantly more likely to have endoscopic and histologic inflammation in the right colon than patients with UC without PSC.	28756053
Inflammation, Peri-Implantitis	Altered Intercellular Communication	These results suggested that probiotics prevent inflammation by affecting host responses rather than improving microbial flora in peri-implant sulci in peri-implantitis patients.	28756115
Inflammation, Arthritis, Weight decreased, Osteoarthritis, Knee	Altered Intercellular Communication	Effects of dietary weight loss with and without exercise on interstitial matrix turnover and tissue inflammation biomarkers in adults with knee osteoarthritis: the Intensive Diet and Exercise for Arthritis trial (IDEA).	28756278
Degenerative polyarthritis, Inflammation, Overweight	Altered Intercellular Communication	Overweight and obese adults with knee OA who lost weight from diet and diet plus exercise reduced serum markers of interstitial matrix turnover and inflammation but not type II collagen degradation.	28756278
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Activated macrophages exhibiting diverse phenotypes and various functions contribute to the pathogenesis or amelioration of different diseases like cancer, inflammation, and infectious and autoimmune diseases.	28756520
Inflammation, ASF1A gene, Cartilage damage, Erosion of bone	Altered Intercellular Communication	We found that CypA aggravated the severity of CIA in mice, as assessed by the increase of clinical score of inflammation, cartilage damage, and bone erosion.	28756520
Gastrointestinal inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	Low vitamin D status is linked to increased incidence of food allergy and intestinal inflammation.	28757197
Hyperglycemia, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Chronic hyperglycaemia in type 2 diabetes (T2D) is associated with increased oxidative stress and inflammation.	28757426
Inflammation, Gastrointestinal mucositis, Peri-Implantitis	Altered Intercellular Communication	Some data imply that Metalloproteinase-8 (MMP-8) level examination in peri-implant sulcular fluid (PISF) might be useful for evaluating the condition of peri-implant tissues and monitoring a development of peri-implant inflammation, including both mucositis and peri-implantitis.	28757684
Inflammation, Varicose Ulcer	Altered Intercellular Communication	Sustained high levels of activated polymorphonuclear leukocytes (PMNs) and PMN-derived proteases in the microenvironment of chronic venous leg ulcers (CVLUs) are linked to chronic inflammation and delayed healing.	28758717
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Diabetes at follow-up was also associated with high c-f PWV, however, this relationship was independent of low grade inflammation.	28759613
Arterial Stiffness, Inflammation	Altered Intercellular Communication	The results indicate that low grade inflammation is associated with arterial stiffness in addition to established cardiovascular risk factors.	28759613
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Reliability of EUS indices to detect inflammation in ulcerative colitis.	28760533
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	EUS is a potentially useful modality to assess severity of inflammation in ulcerative colitis (UC).	28760533
Inflammation, cell wall thickening, Hyperemia	Altered Intercellular Communication	The revised EUS-UC score included bowel wall thickening, depth of inflammation, and hyperemia.	28760533
Anemia, Sickle Cell, Inflammation, SLC22A5 gene	Altered Intercellular Communication	Sickle cell disease (SCD) is a genetic disease caused by mutations in the beta globin gene, and inflammation plays a key role in driving many aspects of disease pathology.	28760671
Inflammation, Chronic Fatigue Syndrome	Altered Intercellular Communication	Although some signs of inflammation have been reported previously in patients with myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS), the data are limited and contradictory.	28760971
Inflammation	Altered Intercellular Communication	High-throughput methods now allow us to interrogate the human immune system for multiple markers of inflammation at a scale that was not previously possible.	28760971
vascular inflammations	Altered Intercellular Communication	Smoking cessation reduces the lectin-like low-density lipoprotein receptor index, an independent cardiovascular risk marker of vascular inflammation.	28761986
Inflammation, atherosclerotic	Altered Intercellular Communication	Vessel wall inflammation promotes the destabilization of atherosclerotic plaques.	28761986
Inflammation, Dyslipidemias	Altered Intercellular Communication	The LOX index is closely associated with smoking heaviness as well as dyslipidemia and an inflammation marker.	28761986
Inflammation, Atherosclerosis	Altered Intercellular Communication	Moderate alcohol consumption is causally related to lower risk of atherosclerosis through changes in lipid profiles and inflammation.	28762059
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Background The Proximity Extension Assay proteomics chip provides a large-scale analysis of 92 biomarkers linked to cardiovascular disease or inflammation.	28762762
Communicable Diseases, Inflammation, Periodontal Diseases, Osteopenia	Altered Intercellular Communication	Chronic periodontal disease is an infectious disease consisting of prolonged inflammation of the supporting tooth tissue and resulting in bone loss.	28764802
Inflammation, Neoplasms	Altered Intercellular Communication	Inflammation plays an important role in tumor development and response to therapy.	28764811
Inflammation, Erythema, Swelling	Altered Intercellular Communication	Clinical examination revealed no signs of swelling, redness, or inflammation in the gingival or surrounding soft tissue.	28764980
hydrocortisone, Inflammation, Data types - Address	Altered Intercellular Communication	Compared to IL1b-induced inflammation, HC have increased CD14 levels after vitamin D treatment (p<0.001), whereas the IL1b-induced CD14 expression of AD patients' monocytes did not change after vitamin D treatment (p=0.8).	28765037
Inflammation, Data types - Address	Altered Intercellular Communication	AD patients carrying HLA high-risk haplotypes showed an increased CCL-2 expression after IL1b-induced inflammation compared to intermediate-risk HLA carriers (p=0.05).	28765037
Inflammation, Organ Dysfunction Scores	Altered Intercellular Communication	However, these patients now survive to enter state of chronic critical illness (CCI), persistent low-grade organ dysfunction and poor long-term outcomes driven by the persistent inflammation, immunosuppression and catabolism syndrome (PICS).	28765125
Spondylitis	Altered Intercellular Communication	A chronic inflammatory condition manifesting in young adulthood, ankylosing spondylitis (AS) affects both physical and emotional quality of life (QOL).	28765244
Inflammation, Muscle (organ)	Altered Intercellular Communication	The pathophysiology is multifactorial, with loss of muscle satellite cells, changes in hormonal systems, chronic inflammation, oxidative stress and anabolic resistance to protein utilisation all implicated.	28765418
Inflammation, Muscle (organ)	Altered Intercellular Communication	The pathophysiology is multifactorial, with loss of muscle satellite cells, changes in hormonal systems, chronic inflammation, oxidative stress and anabolic resistance to protein utilisation all implicated.	28765418
Inflammatory disease of mucous membrane, Gastritis, Atrophic	Altered Intercellular Communication	Anti-CagA-IgG seropositivity was strongly associated with atrophic gastritis, increased mucosal inflammation according to the Sydney score, IL-8 and cagA mRNA expression.	28765692
Inflammation	Altered Intercellular Communication	The core peri-implant microbiome harbours taxa from genera often associated with periodontal inflammation.	28766745
Inflammation, hyperthermia treatment, Hyperemia	Altered Intercellular Communication	The signs of inflammation such as hyperemia and hyperthermia might suggest the possible participation of inflammatory mediators.	28766916
IgG4-Related Sclerosing Disease	Altered Intercellular Communication	IgG4-related disease is an immune-mediated fibro-inflammatory condition that affects multiple organ systems.	28768224
Sepsis, Communicable Diseases, Inflammation, Endotoxemia	Altered Intercellular Communication	The pattern of change in the postoperative period of intestinal permeability, systemic endotoxemia and elastase concentration is significantly higher in patients in whom sepsis develops, while the concentration of IL-1b, IL-6, and CRP does not permit to distinguish infection from inflammation.	28768258
Inflammation, Carcinoma, Transitional Cell, Neoplasms, Necrosis	Altered Intercellular Communication	Tumour front inflammation and necrosis are independent prognostic predictors in high-grade urothelial carcinoma of the bladder.	28768702
Inflammation, Malignant Neoplasms, Necrosis	Altered Intercellular Communication	Inflammation and necrosis have been associated with prognosis in multiple epithelial malignancies.	28768702
Inflammation, Carcinoma, Neoplasms, Necrosis	Altered Intercellular Communication	The relationship of inflammation and necrosis with stage, nodal status, carcinoma in situ, tumour size, margin status and vascular space invasion and the impact on relapse-free and disease-specific survival were calculated using appropriate statistical tests.	28768702
Inflammation, Necrosis	Altered Intercellular Communication	On multivariate analysis, invasive front inflammation (p=0.003) and necrosis (p=0.000) were independent predictors of relapse-free survival.	28768702
Inflammation, Necrosis	Altered Intercellular Communication	Both invasive front inflammation (p=0.009) and necrosis (p=0.002) again were independent predictors of disease-specific survival.	28768702
Inflammation, Carcinoma	Altered Intercellular Communication	For pathological features, low invasive front inflammation was associated with lymphovascular space invasion (p=0.008), a positive soft tissue margin (p=0.028) and carcinoma in situ (p=0.042).	28768702
Inflammation, Carcinoma, Transitional Cell, Necrosis	Altered Intercellular Communication	Necrosis and invasive front inflammation are additional histological variables with independent prognostic relevance in high-grade urothelial carcinoma of the bladder.	28768702
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Our data could indicate that LOY affects secondary outcome via other mechanisms than inflammation in the atherosclerotic plaque.	28768751
Inflammation, Malaria	Altered Intercellular Communication	We measured biomarkers of nutritional and inflammation status and malaria.	28768839
deficiency aspects, Hematoma, Subdural, Chronic	Altered Intercellular Communication	However, the relationship between milder head trauma-such as chronic subdural hematoma - and the occurrence of hormonal deficiency is uncertain.	28768968
Inflammation	Altered Intercellular Communication	The pathophysiology is poorly understood, but it has been suggested that inflammation and oxidative stress may play a role.	28769556
Inflammation, Primary malignant neoplasm, Hemorrhage, Fibrosis Assessment, Edema	Altered Intercellular Communication	41 patients (66.1%) were pathologically diagnosed with cancer, 10 were diagnosed with inflammation, 7 with fibrosis, and 4 with edema, hemorrhage and other lesions.	28770963
Inflammation, Hypertension, CTCAE, Chronic Kidney Diseases	Altered Intercellular Communication	A hypothesized mechanism linking hypertension and progressive chronic kidney disease (CKD) is the innate immune response and inflammation.	28771472
Adult Glioblastoma, Glioblastoma Multiforme Pathway	Altered Intercellular Communication	The perivascular niche is critical for intercellular communication between resident cell types in glioblastoma (GBM), and it plays a vital role in maintaining the glioma stem cell (GSC) microenvironment.	28771552
Sepsis, Inflammation, Septic Shock	Altered Intercellular Communication	In addition, 20 patients with post-surgical inflammation, 20 patients with sepsis or septic shock were included and TNFa was determined following ex vivo stimulation of whole blood with 500 pg/mL LPS.	28771573
Airway structure, Asthma, Occupational	Altered Intercellular Communication	Assessment of eosinophilic airway inflammation as a contribution to the diagnosis of occupational asthma.	28771844
Inflammation	Altered Intercellular Communication	Subjects with abnormal T-axis showed higher levels of subclinical inflammation, hs-troponin I and hs-NT-proBNP (p < 0.001 for all).	28772106
Primary malignant neoplasm	Altered Intercellular Communication	Nivolumab Enhances the Inflammation of the Irradiation Field in Advanced Non-Small Cell Lung Cancer.	28774862
Inflammation, Depression, CTCAE, Diabetic Angiopathies	Altered Intercellular Communication	Elevated innate inflammation may be common to both depression and macrovascular diabetes complications, but these findings require replication.	28776084
Intraocular inflammation, Ocular syphilis, Uveitis	Altered Intercellular Communication	PurposeTo present the patient profiles, clinical presentations and visual outcomes in those diagnosed with ocular syphilis, attending a subspecialist uveitis service in northern England over a 15-year period.Patients and methodsRetrospective observational case series of patients presenting between January 2002 and December 2016.ResultsA total of 50 eyes of 34 patients had intraocular inflammation due to syphilis.	28776596
Inflammation, Hemorrhage, Peri-Implantitis, Suppuration, Communicable Diseases, Osteopenia	Altered Intercellular Communication	Peri-implantitis is an infectious disease characterized by inflammation of the tissues surrounding the implant, bleeding on probing with or without suppuration, and bone loss.	28778496
Inflammation	Altered Intercellular Communication	This situation could be related to chronic inflammation and HDL metabolism.	28778575
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Increased inflammation and impaired endothelial function may be pathways by which chronic PTSD increases cardiovascular disease risk.	28778657
Inflammation	Altered Intercellular Communication	Systemic inflammation and immune response are the major factors influencing the outcome and quality of patient with AECOPD.	28779230
Inflammation, Orbital lymphoma	Altered Intercellular Communication	Diffusivity of intraorbital lymphoma vs. inflammation: comparison of single shot turbo spin echo and multishot echo planar imaging techniques.	28779398
Inflammation, Lymphoma	Altered Intercellular Communication	Twenty-nine patients with pathologically confirmed lymphomas and 39 patients with inflammation were imaged with a 3.0-T system.	28779398
Inflammation, Lymphoma	Altered Intercellular Communication	The ADCs derived from the TSE DWI of the lymphomas (0.68 +- 0.14 x 10-3 mm2/s) were significantly lower than those of the inflammation cases (1.04 +- 0.39 x 10-3 mm2/s; p < 0.001).	28779398
Inflammation, Lymphoma	Altered Intercellular Communication	The ADCs derived from MSh DWI could not be used to separate the lymphomas from the inflammation (1.16 +- 0.43 x 10-3 mm2/s vs. 1.36 +- 0.48 x 10-3 mm2/s; p = 0.06).	28779398
Inflammation, Lymphoma	Altered Intercellular Communication	Conventional sequences also could not separate the lymphomas from the inflammation (p > 0.05).	28779398
Inflammation, Orbital lymphoma	Altered Intercellular Communication	The ADCs derived from TSE DWI might help to differentiate orbital lymphomas from inflammation.	28779398
Inflammation, Lymphoma	Altered Intercellular Communication	* ADC of lymphoma was significantly lower than that of inflammation.	28779398
Pneumonia, Meningitis, Airway structure, Sepsis, Bronchitis, Respiratory Tract Infections	Altered Intercellular Communication	The samples were collected from children aged 0-14 years with conditions such as respiratory tract infections (upper airway inflammation, bronchitis, and pneumonia), meningitis, and sepsis.	28779495
Inflammation, Malnutrition, Obesity	Altered Intercellular Communication	Obesity and malnutrition similarly alter the renin-angiotensin system and inflammation in mice and human adipose.	28779634
Inflammation, Metabolic Diseases	Altered Intercellular Communication	A similar profile was observed in the adipose tissue of obese and malnourished humans, supporting the critical role of inflammation and RAS as mediators of metabolic disorders.	28779634
Inflammation, Coronary Artery Disease, Heart failure	Altered Intercellular Communication	Inflammation is a shared mechanism in coronary artery disease (CAD) and subsequent heart failure (HF), and circulating monocyte and lymphocyte counts predict CAD severity and outcomes.	28779870
Communicable Diseases, Malnutrition, Diarrhea, Inflammation	Altered Intercellular Communication	The impact of enteroaggregative E. coli (EAEC) infection on childhood malnutrition and inflammation has been suggested, regardless of diarrhea.	28780245
Hereditary Autoinflammatory Diseases, Inflammation, Fever, CTCAE, Brucellosis, Familial Mediterranean Fever	Altered Intercellular Communication	Familial Mediterranean fever (FMF) is a genetic autoinflammatory disease characterized by recurrent fever with serosal inflammation.	28781304
Inflammation, Necrosis	Altered Intercellular Communication	In her first liver biopsy, necrosis and inflammation was limited to the centrilobular area, while the second biopsy showed different findings.	28781316
Arthritis	Altered Intercellular Communication	Down-regulation of miR-10a-5p in synoviocytes contributes to TBX5-controlled joint inflammation.	28782180
Refractory anemias, Inflammation, Arthritis	Altered Intercellular Communication	We conclude that miR-10a-5p in a relation with TBX5 regulates joint inflammation in arthritis, which would serve as a diagnostic and therapeutic target for RA treatment.	28782180
Muscle Weakness, Inflammation, Edema, Disease remission	Altered Intercellular Communication	Inflammation and focal or generalized muscle edema were present on US in the remaining five patients with muscular weakness suggesting active disease.	28782262
Inflammation, Cystic artery pseudoaneurysm, Traumatic injury, Cholecystitis	Altered Intercellular Communication	Cystic artery pseudoaneurysm is a rare entity most closely associated with trauma to the biliary vasculature (usually iatrogenic) or inflammation from adjacent cholecystitis.	28782418
Inflammation, Benign prostatic hypertrophy	Altered Intercellular Communication	Yongdamsagan-tang, a traditional herbal formula, inhibits cell growth through the suppression of proliferation and inflammation in benign prostatic hyperplasia epithelial-1 cells.	28782621
Inflammation, Ischemic stroke	Altered Intercellular Communication	Acute ischaemic stroke (AIS) triggers both systemic and neurovascular inflammation, influencing poststroke recovery.	28783210
Inflammation, Reperfusion Injury	Altered Intercellular Communication	In smokers with AIS, inflammation might be further upregulated, increasing ischaemia/reperfusion injury.	28783210
Airway structure, Allergic sensitization	Altered Intercellular Communication	We cross-sectionally investigated the relationships among respiratory symptoms and function, airway inflammation, allergen sensitization, and indoor allergen concentration.	28783215
Airway structure, Atopy	Altered Intercellular Communication	In atopic children, sensitizing allergens in the indoor environment may increase airway inflammation worsening pulmonary function.	28783215
Gastroesophageal reflux disease, Inflammation	Altered Intercellular Communication	The PMA gingival indexes, as a measurement for gingival inflammation, and OHI-S, as a measure for oral hygiene, in the GERD patients were significantly higher than in either of the controls (all P < 0.05).	28784097
Inflammation, Leptomeningitis	Altered Intercellular Communication	Teaching NeuroImages: Cerebral amyloid angiopathy-related inflammation presenting with isolated leptomeningitis.	28784645
Inflammation, Reperfusion Injury	Altered Intercellular Communication	Here, we investigated the role of serum iron in the sterile inflammation that follows kidney ischemia-reperfusion injury.	28784700
Inflammation, Reperfusion Injury	Altered Intercellular Communication	In mice, systemic iron overload protected against renal ischemia-reperfusion injury-associated sterile inflammation.	28784700
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Several circulating proteins involved in phosphate homeostasis, inflammation, apoptosis, extracellular matrix remodeling, angiogenesis, and endothelial dysfunction were associated with worsening kidney function.	28784837
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Short-term treatment with eicosapentaenoic acid improves inflammation and affects colonic differentiation markers and microbiota in patients with ulcerative colitis.	28785079
Inflammation	Altered Intercellular Communication	EPA-FFA improved endoscopic and histological inflammation and induced IL-10, SOCS3, HES1 and KLF4 in compliant and responder patients.	28785079
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In conclusion, EPA-FFA supplementation reduced mucosal inflammation, promoted goblet cells differentiation and modulated intestinal microbiota composition in long-standing UC patients.	28785079
Inflammation, Respiration Disorders, Thrombus, Traumatic injury, terminal cancer, Morbid obesity	Altered Intercellular Communication	Those with recurring thrombotic episodes, cardiorespiratory disease, terminal cancer, morbid obesity, penetrating trauma or significant inflammation were excluded.	28787773
Inflammation, Esophagitis	Altered Intercellular Communication	"Lichenoid esophagitis" is a descriptive term for a lichenoid pattern of inflammation in the esophagus for which a precise histologic diagnosis cannot be established.	28789612
Inflammation, Esophagitis	Altered Intercellular Communication	Lichenoid esophagitis is an appropriate diagnostic term when clinical, histologic and laboratory findings do not allow for specific categorization of lichenoid inflammation in the esophagus.	28789612
Inflammation, Carotid Stenosis, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Type 2 diabetes mellitus (T2DM) is characterized by increased inflammation and an elevated risk for embolization of carotid artery stenosis (CAS).	28789657
Inflammatory Bowel Diseases, Inflammation, Adenocarcinoma of large intestine	Altered Intercellular Communication	Colonic inflammation seen in inflammatory bowel disease (IBD) predisposes to the development of colorectal adenocarcinoma.	28790093
Inflammation, Dysplasia, Necrotizing enterocolitis in fetus OR newborn	Altered Intercellular Communication	Dysplasia from chronic inflammation leading to neuroendocrine cell differentiation may be responsible for NEC development, though this finding has not been seen consistently.	28790093
Chronic disease of skin, Inflammation, Psoriasis	Altered Intercellular Communication	Psoriasis is a chronic skin disease characterized by abnormal keratinocyte proliferation and differentiation, inflammation, and angiogenesis.	28790132
Inflammation, Primary malignant neoplasm, Psoriasis, Metabolic Syndrome X, Chronic inflammatory disorder	Altered Intercellular Communication	Psoriasis is a chronic inflammatory disease that affects skin and is associated with systemic inflammation and many serious comorbidities ranging from metabolic syndrome to cancer.	28790368
Inflammation, Arthritis, Psoriatic	Altered Intercellular Communication	We found that signs of systemic inflammation were present in most of the patients, correlated with the severity of the disease, and pointed to IL-6 involvement in the pathogenesis of psoriatic arthritis.	28790368
Inflammation, Aortic Aneurysm, Thoracic	Altered Intercellular Communication	Curcumin attenuates the development of thoracic aortic aneurysm by inhibiting VEGF expression and inflammation.	28791384
Crohn Disease	Altered Intercellular Communication	Crohn's disease (CD) is an inflammatory condition of the gastrointestinal tract that can affect the musculoskeletal system.	28791436
Fibrosis, Liver, Inflammation, Liver damage	Altered Intercellular Communication	Levels of leptin and biochemical markers of liver cell damage, liver fibrosis, inflammation and oxidative stress, and hepatocyte apoptosis were significantly higher in subjects in Q 1 than in those in Q 2, Q 3, or Q 4.	28791501
Inflammation, Tumor necrosis, Neoplasms	Altered Intercellular Communication	Inflammation contributes to tumor progression and can be induced by excessive production of pro-inflammatory cytokines such as interleukin-6 (IL-6), interleukin-8 (IL-8) and tumor necrosis factor-a (TNF-a).	28791816
Inflammation, Lung Diseases, Obstructive	Altered Intercellular Communication	These results suggest that the most important marker of inflammation in mild-to-moderate obstructive lung disease is not microbiology-dependent.	28791839
Inflammation, Joints	Altered Intercellular Communication	This may lead to increased macrophage and osteoclast activation, resulting in the increased local inflammation and bone resorption present in RA joints.	28792533
Inflammation, Interstitial Fibrosis Assessment, Kidney damage	Altered Intercellular Communication	In human HN, inflammation involving complement C3 activation and macrophage infiltration as well as interactions between them, may play important roles in the pathogenesis and progression of interstitial fibrosis and kidney damage.	28793954
Inflammation, "Alzheimers Disease", Data types - Address	Altered Intercellular Communication	Increasing evidence suggests that inflammation is involved in Alzheimer's disease (AD) pathology.	28794151
Inflammation, Pulmonary Hypertension	Altered Intercellular Communication	Association of Pulmonary Hypertension With Inflammation and Fluid Overload in Hemodialysis Patients.	28794293
Hypernatremia, Cardiac Hypertrophy, Inflammation, Pulmonary Hypertension	Altered Intercellular Communication	Pulmonary hypertension, cardiac hypertrophy, fluid overload, and inflammation were associated to each other in hemodialysis patients, providing insight into its pathogenesis.	28794293
Lymphoma of kidney, Adrenal cortical hypofunction	Altered Intercellular Communication	The Clinical and Hormonal Characteristics of Primary Adrenal Lymphomas: The Necessity of Early Detection of Adrenal Insufficiency.	28794358
Inflammation, Hypoproteinemia	Altered Intercellular Communication	After 17 months of treatment, crizotinib was switched to alectinib, followed by the recovery of hypoproteinemia and systemic inflammation.	28794366
Inflammation, Renal cyst	Altered Intercellular Communication	Switching to alectinib may be beneficial in patients demonstrating crizotinib-associated complex renal cysts with systemic inflammation and exhaustion.	28794366
Vasculitis	Altered Intercellular Communication	An extended high-frequency ultrasound protocol for detection of vessel wall inflammation.	28795494
Communicable Diseases, Inflammation, Arteritis	Altered Intercellular Communication	In the groups with sonographic signs implying arteritis (n = 29), 20 patients had a clinical diagnosis of arteritis, whereas eight patients had another main diagnosis such as malignancy/other inflammatory or infectious disease complicated by inflammation of the vessel wall.	28795494
Vasculitis	Altered Intercellular Communication	In case of atypical vessel wall inflammation, other main diagnoses should be considered.	28795494
Inflammation, Colorectal Carcinoma, Malignant Neoplasms	Altered Intercellular Communication	Colorectal cancer (CRC) is one of the most common malignant tumors worldwide, which is a heterogeneous disease and main risk factors are associated with inflammation, family history, genetic mutations, epigenetics, and so on.	28796265
Inflammation, Obesity	Altered Intercellular Communication	Lean body mass and creatine kinase are associated with reduced inflammation in obesity.	28796313
Inflammation, Obesity	Altered Intercellular Communication	Obesity is associated with inflammation, but the role of lean mass and creatine kinase (CK) on the inflammatory process is less known.	28796313
Inflammation, Obesity	Altered Intercellular Communication	Hypothetically, lean mass has a favourable effect on obesity-related inflammation, and CK may play a role as an inhibitor of inflammation in obesity.	28796313
Inflammation, HIV Infections	Altered Intercellular Communication	Inflammation occurs after HIV infection and persists, despite highly active antiretroviral therapy (HAART).	28796748
Inflammation, Gastrointestinal mucositis, Malignant Head and Neck Neoplasm	Altered Intercellular Communication	Oral mucositis is inflammation of mucosa of oral cavity which is an inevitable and acute side effect in patients undergoing chemoradiotherapy for head & neck cancer.	28797456
Inflammation, Prostate carcinoma	Altered Intercellular Communication	We propose that the urinary microbiome may influence chronic inflammation observed in the prostate, leading to prostate cancer development and progression.	28797714
Primary malignant neoplasm, prostatitis	Altered Intercellular Communication	We determined the association between bacterial species and the presence or absence of cancer, cancer grade, and type and degree of prostate inflammation.	28797714
Primary malignant neoplasm, Malignant Neoplasms, prostatitis	Altered Intercellular Communication	Many species, including known uropathogens, were significantly and differentially abundant among cancer and benign samples, in low vs higher grade cancers and in relation to prostate inflammation type and degree.	28797714
Inflammation, Autoimmune Hypophysitis	Altered Intercellular Communication	Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm.	28799078
Intestinal metaplasia, Inflammation	Altered Intercellular Communication	intestinal metaplasia and degree of inflammation, were inconclusive between the two groups.	28799264
Inflammation, Cholelithiasis, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	Biomarkers of insulin resistance, systemic inflammation and genetic obesity or type 2 diabetes risk alleles seem to be associated with gallstone disease.	28799434
Data types - Address	Altered Intercellular Communication	Our findings suggest that AD GRNs show significant enrichment for key signaling mechanisms involved in neurotransmission.	28800327
Cognition Disorders, Data types - Address	Altered Intercellular Communication	Among the prioritized genes, well-known AD genes were prominent in synaptic transmission, implicated in cognitive deficits.	28800327
Plaque, Atherosclerotic	Altered Intercellular Communication	Variability in quantitative analysis of atherosclerotic plaque inflammation using 18F-FDG PET/CT.	28800625
dendritic lamellar body, Pervasive Development Disorder	Altered Intercellular Communication	The postsynaptic protein, synaptopodin (SYNPO) was significantly down-regulated in both DLB and PDD subgroups, suggesting a defective synaptic transmission in the demented patients.	28800743
physiopathological	Altered Intercellular Communication	Environmental enteric dysfunction (EED) is a subacute inflammatory condition of the small intestinal mucosa with unclear aetiology that may account for more than 40% of all cases of stunting.	28801442
Liver carcinoma	Altered Intercellular Communication	An internally validated new clinical and inflammation-based prognostic score for patients with advanced hepatocellular carcinoma treated with sorafenib.	28801777
Communicable Diseases, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Calprotectin and lactoferrin are released by the gastrointestinal tract in response to infection and mucosal inflammation.	28801865
Compact Disk Interactive, Gastrointestinal inflammation	Altered Intercellular Communication	Both faecal calprotectin and lactoferrin were higher in patients with CDI, especially in those with detectable toxin in faeces, suggesting a correlation between intestinal inflammation and toxins in stools.	28801865
Inflammation	Altered Intercellular Communication	Cytochrome c levels did not increase after cardiac surgery and was not associated with the degree of inflammation or clinical outcomes.	28802789
Dyspnea, Inflammation, Depression, CTCAE, Pain Distress Question	Altered Intercellular Communication	Worse QoL was associated with increased systemic inflammation (mGPS = 1 b = -0.12, P = 0.003; mGPS = 2 b = -0.09, P = 0.023), lower physical performance (b = 0.17, P < 0.001), reduced appetite (b = -0.15, P < 0.001), breathlessness (b = -0.11, P = 0.004), pain (b = -0.14, P = 0.002), and higher depression severity (b = -0.27, P < 0.001).	28803091
ACSM3 gene, Inflammation, Subarachnoid Hemorrhage	Altered Intercellular Communication	Inflammation following subarachnoid hemorrhage (SAH) involves numerous mediators with biomarker properties.	28803177
Sepsis, Communicable Diseases, Inflammation, Endotoxemia	Altered Intercellular Communication	The pattern of change of intestinal permeability, systemic endotoxemia, and elastase concentration in the postoperative period is significantly higher in patients in whom sepsis develops, while the concentration of IL-1b, IL-6 and CRP do not permit to distinguish infection from inflammation.	28803860
Inflammation, Non-alcoholic Fatty Liver Disease, Obesity	Altered Intercellular Communication	Non-alcoholic fatty liver disease (NAFLD) affects 20%-30% of adults with risk factors like obesity and insulin resistance putatively acting through chronic low-grade inflammation.	28804947
Inflammation, Periodontitis, Non-alcoholic Fatty Liver Disease	Altered Intercellular Communication	Because periodontitis elicits low-grade inflammation, we hypothesized that it could contribute to NAFLD occurrence.	28804947
Inflammation, Traumatic injury, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	Hypoxemic Patients With Bilateral Infiltrates Treated With High-Flow Nasal Cannula Present a Similar Pattern of Biomarkers of Inflammation and Injury to Acute Respiratory Distress Syndrome Patients.	28806218
glycation, Endothelium, Inflammation, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	We measured plasma biomarkers of lung epithelial injury (receptor for advanced glycation end products and surfactant protein D) and endothelial injury (angiopoietin-2) and inflammation (interleukin-6, interleukin-8, and interleukin-33 and soluble suppression of tumorigenicity-2) within 24 hours of acute respiratory distress syndrome onset.	28806218
Paraganglioma	Altered Intercellular Communication	Her initial FDG PET demonstrated brown adipose tissue hyperactivation, which may have been caused by the combination of hormonal changes in pregnancy and the paraganglioma.	28806264
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	Although possible in ulcerative colitis (UC) patients, the chronic inflammation may increase the procedural risks and reduce the complete resection rate.	28806821
Inflammation, Necrotizing fasciitis, Necrosis	Altered Intercellular Communication	Necrotizing myositis is a rare but life-threatening soft-tissue infection characterized by rapidly spreading inflammation and subsequent necrosis of the affected tissue.	28807000
Inflammation, Fracture	Altered Intercellular Communication	Unlike in simple stress fracture, long-term antibiotic administration and drainage surgery were required to suppress the inflammation.	28807072
Inflammation, Inflammatory disorder	Altered Intercellular Communication	Systemic inflammation was primarily assessed by neutrophil-lymphocyte ratio (NLR), where a ratio >4 is prognostic across several inflammatory diseases and correlates strongly with elevated plasma levels of pro-inflammatory cytokines.	28807718
Inflammation, Abnormal sudomotor regulation	Altered Intercellular Communication	Delayed HRR, a robust measure of parasympathetic dysfunction, is independently associated with leukocyte ratios indicative of systemic inflammation.	28807718
Weakness, Myositis, CTCAE 5.0, Myositis	Altered Intercellular Communication	Myositis is characterised by muscle inflammation and weakness.	28808260
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Plasma alpha-L-fucosidase activity in chronic inflammation and autoimmune disorders in a pediatric cohort of hospitalized patients.	28808940
Autoimmune Diseases, Inflammation	Altered Intercellular Communication	The result of the present study should encourage further research on FUCA-1 as a marker of chronic inflammation and autoimmunity.	28808940
APP gene, Inflammation, Aortic Aneurysm, Abdominal, Rupture	Altered Intercellular Communication	Inflammation detected through the uptake of ultrasmall superparamagnetic particles of iron oxide (USPIO) on magnetic resonance imaging (MRI) and finite element (FE) modelling of tissue stress both hold potential in the assessment of abdominal aortic aneurysm (AAA) rupture risk.	28808955
APP gene, Inflammation	Altered Intercellular Communication	It is suggested that cellular inflammation and stress may represent different but complimentary aspects of AAA disease progression.	28808955
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Repeated exposure to systemic inflammation and risk of new depressive symptoms among older adults.	28809860
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Evidence on systemic inflammation as a risk factor for future depression is inconsistent, possibly due to a lack of regard for persistency of exposure.	28809860
Inflammation, Bipolar Disorder	Altered Intercellular Communication	In further analyses, 2 vs 0 occasions of inflammation were associated with increased odds of developing depressive symptoms among women (odds ratio (OR)=2.75, 95% CI=1.53, 4.95), but not among men (OR=0.70, 95% CI=0.29, 1.68); P-for-sex interaction=0.035.	28809860
Inflammation, Bipolar Disorder	Altered Intercellular Communication	In this cohort study of older adults, repeated but not transient exposure to systemic inflammation was associated with increased risk of future depressive symptoms among women; this subgroup finding requires confirmation of validity.	28809860
Inflammation, Spinal Cord Injuries	Altered Intercellular Communication	FEV1 and FVC and systemic inflammation in a spinal cord injury cohort.	28810847
Inflammation	Altered Intercellular Communication	Systemic inflammation has been associated with reduced pulmonary function in individuals with and without chronic medical conditions.	28810847
Inflammation, Spinal Cord Injuries, Stanford Cancer Institute	Altered Intercellular Communication	Individuals with chronic spinal cord injury (SCI) have clinical characteristics that promote systemic inflammation and also have reduced pulmonary function.	28810847
Inflammation, Stanford Cancer Institute	Altered Intercellular Communication	We sought to assess the associations between biomarkers of systemic inflammation with pulmonary function in a chronic SCI cohort, adjusting for other potential confounding factors.	28810847
Inflammation, Stanford Cancer Institute	Altered Intercellular Communication	This finding suggests that systemic inflammation associated with chronic SCI may contribute to reduced pulmonary function.	28810847
Inflammation, Disease	Altered Intercellular Communication	Low DHEAS/cortisol ratios are associated with more severe diseases, inflammation, and CIRCI and can serve as a prognostic marker.	28810889
Granulomatous inflammation	Altered Intercellular Communication	Biopsy of the foot revealed granulomatous inflammation with predominantly lymphoplasmacytic infiltrate and multinucleated giant cells.	28810997
glycation, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	The soluble receptor for advanced glycation end products (sRAGE) may be protective against inflammation associated with obesity and type 2 diabetes (T2DM).	28811295
Inflammation, Family history	Altered Intercellular Communication	In conclusion, circulating miR-200c is up-regulated in FH, probably due to oxidative stress and inflammation and via a miR-33a/b-ZEB1-dependent mechanism.	28811385
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Systemic inflammation, measured by C-reactive protein (CRP), is an important risk factor for cardiovascular disease (CVD) and mortality.	28811734
Inflammation, AKAP4 protein, human	Altered Intercellular Communication	We investigated whether aerobic exercise training (AEXT) affects African Americans with high inflammation (HI) the same way it does African Americans with low inflammation (LI) in terms of CVD risk factors.	28811734
Inflammation	Altered Intercellular Communication	This may indicate that, in African Americans with high inflammation, AEXT alone may not be enough to reap the same benefits as their low-inflammation peers in terms of CVD risk modification.	28811734
Sick Sinus Syndrome, Dacryoadenitis, Thyroid associated opthalmopathies, Orbital Pseudotumor	Altered Intercellular Communication	This is a retrospective case description of a single female patient found to have concomitant bilateral silent sinus syndrome, bilateral thyroid eye disease, unilateral dacryoadenitis, and idiopathic orbital inflammation that presented as progressive unilateral right-sided proptosis.	28812921
Aneurysm, Inflammation, Traumatic injury, Mobius II syndrome	Altered Intercellular Communication	Although the exact etiology is not known, inflammation, trauma, degenerative changes, and congenital weakness of venous wall have all been proposed as causes of venous aneurysms.	28813774
Inflammation, Tumor necrosis, Endothelial dysfunction	Altered Intercellular Communication	The biomarkers were representative of several biologic processes: apoptosis (soluble Fas), inflammation (soluble tumor necrosis factor receptor 1, interleukin 6, interleukin 8) and endothelial dysfunction, (angiopoietin 1, angiopoietin 2, and soluble vascular cell adhesion molecule 1).	28814331
Inflammation	Altered Intercellular Communication	The prognostic role of the neutrophil-to-lymphocyte ratio (NLR) and the eosinophil-to-lymphocyte ratio (ELR) as potential markers of inflammation has already been discussed.	28814353
Inflammation	Altered Intercellular Communication	Unlike eosinophilic inflammation, the inflammatory patterns seen in noneosinophilic CRSwNP are still poorly understood.	28814353
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Calprotectin as a marker of inflammation in patients with early rheumatoid arthritis.	28814431
Hypertension, CTCAE, Myelolipoma of adrenal gland, "Pituitary-dependent Cushings disease", Diabetes Mellitus	Altered Intercellular Communication	In this article, hormonal evaluation in a middle-aged woman with diabetes, hypertension and incidentally discovered unilateral adrenal myelolipoma revealed underlying subclinical Cushing's disease.	28814582
ARCN1 gene, Inflammation	Altered Intercellular Communication	Platelets may actively participate in inflammation in COPD.	28814854
Fatty Liver Disease, Necrosis with inflammation	Altered Intercellular Communication	This cohort was 51% females, mean age 60 years (25/82), 67% pretreated, 70% associated NASH, 67% with severe necro-inflammation (severity score 3-Fibromax), 37% with comorbidities, 10.4% with Child Pugh A6, 0.5% B7.	28816020
Neurodegenerative Disorders, Inflammation, Nerve Degeneration, "Alzheimers Disease", Data types - Address, Transient Ischemic Attack	Altered Intercellular Communication	Alzheimer's disease (AD) is a severe neurodegenerative brain disorder characterized by beta-amyloid plaques, Tau pathology, inflammation, neurodegeneration, and cerebrovascular dysfunction.	28816110
Dacryoadenitis	Altered Intercellular Communication	The role of biopsy in lacrimal gland inflammation: A clinicopathologic study.	28816552
Dacryoadenitis	Altered Intercellular Communication	To determine the causes of lacrimal gland inflammation based on histopathology and systemic evaluation.	28816552
Inflammation, Dacryoadenitis, Granulomatosis, Malignant myoepithelioma, Lipogranuloma, Fibrosis Assessment, Eosinophilic granulomatosis with polyangiitis, Lymphoma, Granulomatosis with polyangiitis, LACRIMAL INFLAMMATION, "Sjogrens Syndrome", Systemic Vasculitis	Altered Intercellular Communication	The histopathologic findings of the 60 patients showed that 37 (61.7%) had identifiable types of lacrimal inflammation including 10 with Sjogren's syndrome, seven with sarcoidal reaction, six with feature of granulomatosis with polyangiitis (formerly known as Wegener's granulomatosis), five with lymphoma, two with sclerosing inflammation, two with IgG4-related dacryoadenitis, and one patient each with infectious dacryoadenitis, myoepithelial carcinoma, xanthogranuloma, eosinophilic angiocentric fibrosis, and eosinophilic allergic granulomatous nodule.	28816552
Sore to touch, Dacryoadenitis, Edema, Erythema	Altered Intercellular Communication	We recommend that in patients presenting with lacrimal gland inflammation (i.e., erythema, edema, tenderness) in which the specific diagnosis cannot be made clinically and on imaging, biopsy is warranted for accurate diagnosis and appropriate treatment.	28816552
Sensorineural Hearing Loss (disorder), Arachnoiditis, Jugular Foramen Schwannoma	Altered Intercellular Communication	The aim of this case report was to present the excision of a large jugular foramen schwannoma via the retrosigmoid approach and to describe the improvement of sensorineural hearing loss related to arachnoid inflammations due to chronic arachnoiditis after suboccipital craniectomy.	28816700
Sepsis	Altered Intercellular Communication	Sepsis presents with similar profiles in adult and pediatric patients, characterized by enhanced inflammatory hormonal response and by repressed innate immunity, metabolism, and myocardial contractility.	28816920
Gastrointestinal inflammation	Altered Intercellular Communication	Furthermore, the small bowel transit time may not be affected by the grade of small intestinal inflammation.	28816962
Toxic effect, Inflammatory disease of mucous membrane, Febrile Neutropenia, CTCAE	Altered Intercellular Communication	The most common dose-limiting toxicities were febrile neutropenia and mucosal inflammation.	28817190
Inflammation, Primary malignant neoplasm, Obesity	Altered Intercellular Communication	Young Adult Risk Factors for Cancer: Obesity, Inflammation, and Sociobehavioral Mechanisms.	28818242
Inflammation, Obesity	Altered Intercellular Communication	After adjusting for these behavioral variables, sex, and race disparities in obesity and excess inflammation in blacks diminished, whereas the adolescent SES disparity in obesity remained.	28818242
Inflammation, Obesity	Altered Intercellular Communication	Behavioral factors associated with higher risks of obesity and inflammation differed, with the exception of fast food consumption, a risk factor for both.	28818242
Inflammation, Osteoporosis, Chronic disease	Altered Intercellular Communication	Inflammation may contribute to osteoporosis, as it does to many other chronic diseases.	28819125
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	A Preliminary Investigation of the Association of Sleep With Inflammation and Oxidative Stress Biomarkers and Functional Outcomes After Stroke Rehabilitation.	28819157
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	This study examined the association of sleep with inflammation and oxidative stress biomarkers, and with functional outcomes, after stroke rehabilitation.	28819157
Seizures, Inflammation, Hemorrhagic, Cavernous Hemangioma of Brain	Altered Intercellular Communication	Plasma Biomarkers of Inflammation Reflect Seizures and Hemorrhagic Activity of Cerebral Cavernous Malformations.	28819935
Intraocular inflammation	Altered Intercellular Communication	Intraocular inflammation developed in the fellow eye and SO was suspected, which was confirmed by characteristic findings seen on fluorescein angiography.	28820164
Inflammation	Altered Intercellular Communication	Although he responded well initially, he had recurrent inflammation and paradoxical worsening.	28820170
Inflammation	Altered Intercellular Communication	Training-induced changes in inflammation and oxidative stress status correlated with favorable improvements in semen parameters, sperm DNA integrity, and pregnancy rate (P < 0.05).	28820950
Inflammation, Pseudolymphoma	Altered Intercellular Communication	Five cases (three men, two women; age, 40-80 years) had restricted proliferations of atypical/monotypic IgG4+ plasma cells in a background of reactive lymphoid hyperplasia or inflammation.	28821195
Airway structure	Altered Intercellular Communication	Genetic and epigenetic susceptibility of airway inflammation to PM2.5 in school children: new insights from quantile regression.	28821285
Airway structure	Altered Intercellular Communication	The fractional concentration of exhaled nitric oxide (FeNO) is a biomarker of airway inflammation that has proved to be useful in investigations of genetic and epigenetic airway susceptibility to ambient air pollutants.	28821285
Acute Kidney Injury, CTCAE, Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	Inflammation is a key component of both acute kidney injury (AKI) and response to cardiopulmonary bypass.	28821332
Hemorrhage, Chronic inflammation, Neoplasms, Myxoma, Hemosiderosis	Altered Intercellular Communication	Although microscopic examinations revealed enlarged vessels, hemorrhages and hemosiderosis in the left part and high cellularity with chronic inflammation in the right part, spindle-shaped cells in a loose myxoid stroma were observed in both parts of the tumor, consistent with the diagnosis of myxoma.	28822084
Inflammation, Malnutrition, Cachexia	Altered Intercellular Communication	Nineteen fulfilled the ESPEN basic definition, of which 10 had disease-related malnutrition with inflammation and 9 without inflammation, and 20 had cachexia.	28822255
Communicable Diseases	Altered Intercellular Communication	Intensive exercise modifies airway inflammation and infection susceptibility.	28822267
Airway structure	Altered Intercellular Communication	Dysregulation of the TNF-a/IL-1ra balance in EBC and nasal secretions from athletes may reflect the presence of airway inflammation induced by repeated strenuous exercise.	28822267
Inflammation	Altered Intercellular Communication	Inflammation or lymphatic disruption at the site of cannulation can cause the formation of lymphoceles, leading to the patient's discomfort and possibly necessitating intervention.	28822659
Communicable Diseases, Inflammation	Altered Intercellular Communication	Serum C-reactive protein (CRP) increases and albumin decreases in patients with inflammation and infection.	28823374
Pancreatitis	Altered Intercellular Communication	The CRP/albumin ratio is a novel but promising, easy-to-measure, repeatable, non-invasive inflammation-based prognostic score in acute pancreatitis.	28823374
Inflammation, Complement and Coagulation Cascade	Altered Intercellular Communication	Fibrinogen is a crucial role in coagulation cascade and inflammation.	28823490
Inflammation, Brain Injuries, Subarachnoid Hemorrhage, Aneurysmal, ASAH1 gene	Altered Intercellular Communication	We clarified whether serum MIF could be used as a marker of inflammation, brain damage and outcome after aneurysmal subarachnoid hemorrhage (aSAH).	28823650
Inflammation, Brain Injuries, ASAH1 gene	Altered Intercellular Communication	Serum MIF provides information about inflammation, brain injury severity and outcome after aSAH, which can be useful as a complement to clinical data.	28823650
Inflammation, Progranulins, GRN wt Allele	Altered Intercellular Communication	GP88 (progranulin; PGRN) is a secreted 88kDa glycosylated protein, with important functions, including inflammation and tumorigenesis.	28823651
Inflammation	Altered Intercellular Communication	The increased levels of the soluble forms of the two IL-1 receptors IL-1R1 and IL-1R2 suggest the need to dampen IL-1-mediated inflammation at the tissue level.	28823915
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Histological examination is necessary for the exclusion of malignancy and chronic inflammation.	28824310
Retinal Degeneration, Dystrophy, Intraocular inflammation, Chickenpox, Autoimmune retinopathy	Altered Intercellular Communication	Autoimmune retinopathy was suspected on the basis of the clinical presentation, electrophysiology, absence of fundus lesions, retinal degenerations or dystrophies, or intraocular inflammation and temporal association with varicella infection.	28825165
Inflammation, Data types - Address	Altered Intercellular Communication	To address in older subjects (i) the relationships between AD pathology and MIF plasma and cerebrospinal fluid (CSF) levels; and (ii) to investigate whether increased MIF-related systemic and CNS inflammation is associated with clinical disease progression.	28826184
Data types - Address, Trauma, Nervous System	Altered Intercellular Communication	Our study provides evidence that MIF-related inflammation is related to amyloid pathology, tau hyperphosphorylation, and neuronal injury at the early clinical stages of AD.	28826184
Inflammation	Altered Intercellular Communication	These results suggested impaired resolution of inflammation in the absence of Tet2 both in vitro and in vivo.	28826859
Inflammation, Myeloid	Altered Intercellular Communication	Our results show that Tet2 restrains inflammation in murine MPhs and mice, raising the possibility that loss of TET2 function in MPhs may alter the immune environment in the large elderly population with TET2-mutant CHIP and in TET2-mutant myeloid cancer patients.	28826859
vascular inflammations, Psoriasis	Altered Intercellular Communication	The relationship between duration of psoriasis, vascular inflammation, and cardiovascular events.	28826925
vascular inflammations, Psoriasis	Altered Intercellular Communication	Whether psoriasis duration affects risk of vascular inflammation and MACEs has not been well characterized.	28826925
vascular inflammations	Altered Intercellular Communication	Vascular inflammation by fludeoxyglucose F 18 positron emission tomography/computed tomography was significantly associated with disease duration (b = 0.171, P = .002).	28826925
Inflammation, vascular inflammations, Psoriasis, Vascular Diseases	Altered Intercellular Communication	We found detrimental effects of psoriasis duration on vascular inflammation and MACE, suggesting that cumulative duration of exposure to low-grade chronic inflammation may accelerate vascular disease development and MACEs.	28826925
Rhabdomyolysis, Hypothyroidism	Altered Intercellular Communication	Initial laboratory testing showed elevated thyroid stimulating hormone (TSH) and creatine kinase (CK) levels, indicating uncontrolled hypothyroidism with associated rhabdomyolysis.	28827517
Gastric Adenocarcinoma, Primary malignant neoplasm	Altered Intercellular Communication	Systemic Inflammation Response Index (SIRI), cancer stem cells and survival of localised gastric adenocarcinoma after curative resection.	28828692
Refractory anemias	Altered Intercellular Communication	Thus, a close relation of MMP-3 with PAs and PVR indicate that rise in PAs in patients with RA was ascribed to increase in PVR due to underlying systemic inflammation-mediated pulmonary vascular remodeling.	28828748
Overhydration, Inflammation, Endothelial dysfunction, Chronic Kidney Diseases	Altered Intercellular Communication	Extracellular overhydration linked with endothelial dysfunction in the context of inflammation in haemodialysis dependent chronic kidney disease.	28829810
Inflammation, Ischemic stroke	Altered Intercellular Communication	Elevated neutrophil to lymphocyte ratio (NLR) has been reported as a marker for chronic inflammation, associated with poor prognosis in ischemic stroke patients, but there has been no study that investigated its association with ischemic stroke risk.	28829826
Inflammation, Neoplasms	Altered Intercellular Communication	Known neoplasm, inflammation or poor imaging were excluded.	28829975
Inflammation	Altered Intercellular Communication	Compared with those in patients with STEMI, differentially expressed microRNAs in controls and patients with SA or NSTE-ACS were involved in inflammation, protein phosphorylation, and cell adhesion.	28830367
Kidney Failure, Chronic, Inflammation, Chronic Kidney Diseases, Ulcerative Colitis	Altered Intercellular Communication	We hypothesized that a reversal of the physiological stiffness gradient, previously reported in end-stage renal disease, begins in the early stages of chronic kidney disease (CKD) and that chronic inflammation produces a different arterial phenotype in patients with ulcerative colitis (UC).	28830726
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In patients with UC, the stiffness of both elastic and muscular arteries is increased as a consequence of inflammation.	28830726
Tumor necrosis, Inflammation, COL4A2 wt Allele	Altered Intercellular Communication	The results suggest that tumor necrosis factor-mediated inflammation could be associated with vascular changes preceding ICH.	28830973
Pain Distress Question, Inflammation, Pruritus	Altered Intercellular Communication	We applied a systems-based, translational approach to predict, discover, and characterize mediators of pain and itch that are regulated by diet and inflammation.	28831021
ACSM3 gene, Inflammation, Subarachnoid Hemorrhage, Aneurysmal, Tissue injury	Altered Intercellular Communication	A matricellular protein galectin-3 is involved in tissue injury and inflammation, but the role of galectin-3 remains unclear in aneurysmal subarachnoid hemorrhage (SAH).	28831694
Inflammation, Brain Injuries, Cerebral Infarction, Vasospasm	Altered Intercellular Communication	The findings suggest that plasma galectin-3 levels on days 1-3 would be a useful biomarker for predicting subsequent development of delayed cerebral infarction and eventual poor outcome and provide a new candidate, which may mediate between post-SAH early brain injury or inflammation and delayed cerebral infarction without vasospasm.	28831694
Inflammation	Altered Intercellular Communication	Chronic inflammation is the usual cause, but acute trigger finger following partial tendon laceration has also been described.	28832206
Inflammation, Traumatic injury, Malignant Neoplasms	Altered Intercellular Communication	The differential diagnosis is extensive, including: malignancy, trauma, inflammation of the urinary tract, and stones.	28832315
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Long-term treatment with budesonide/formoterol attenuates circulating CRP levels in chronic obstructive pulmonary disease patients of group D. The systemic inflammation is associated with clinical outcome and mortality in chronic obstructive pulmonary disease (COPD) patients.	28832630
Inflammation, Wheezing, Respiratory Failure	Altered Intercellular Communication	Bronchial wheezing predicts inflammation and respiratory failure in fire smoke victims.	28832892
Inflammation, Respiratory Failure, Pulmonary Dysfunction	Altered Intercellular Communication	In victims of fire smoke inhalation, pulmonary wheezing predicts inflammation, pulmonary dysfunction, respiratory failure, and need for intensive care.	28832892
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	The role of inflammation in diabetes development is not fully elucidated.	28834086
Conjunctivitis	Altered Intercellular Communication	Their symptoms, conjunctival inflammation, corneal staining, and visual acuity were compared before and after treatment.	28834819
Inflammatory abnormality of the eye	Altered Intercellular Communication	After epithelial debridement and placement of the PKS for 5 +- 3.7 days, all patients reported significant relief of symptoms, rapid corneal epithelialization, and reduction of ocular surface inflammation.	28834819
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	We found an association between a reduction in the fibrosis stage and continuous glucocorticoid medication, as well as lowered scores of inflammation at last biopsy.	28834875
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	In recent years, lymphocyte-to-monocyte ratio (LMR) has become a novel indirect marker of inflammation, which has been demonstrated to be associated with poor prognosis of oncology and cardiovascular disease.	28834908
Peripheral Arterial Diseases	Altered Intercellular Communication	Endothelial Cell Inflammation and Antioxidant Capacity are Associated With 6-Minute Walk Performance in Patients With Symptomatic Peripheral Artery Disease.	28835113
Inflammation, Peripheral Arterial Diseases	Altered Intercellular Communication	We determined whether 6-minute walk total distance and pain-free distance were associated with circulating biomarkers of antioxidant capacity and inflammation and with cultured endothelial cell inflammation, oxidative stress, and apoptosis in 251 patients with symptomatic peripheral artery disease (PAD).	28835113
Inflammation, Allergy - Charge Type Reason, Infection, Edema, Abnormal renal function, Endocrine System Diseases, Traumatic injury, Primary Hypothyroidism	Altered Intercellular Communication	Common causes of periorbital edema include infections, inflammation, trauma, allergy, kidney or cardiac dysfunction, and endocrine disorders such as primary hypothyroidism.	28835258
Inflammation, Depression, CTCAE	Altered Intercellular Communication	The role of inflammation in the pathophysiology of depression remains unknown; however, the symptom cluster of sickness behavior is more clearly related to inflammation.	28835295
Amyotrophic Lateral Sclerosis	Altered Intercellular Communication	Our results indicate that hormonal factors may be important etiologic factors in ALS; however, a full understanding requires further investigation.	28835399
Malignant Neoplasms	Altered Intercellular Communication	The serum macrophage inhibitory cytokine-1 (MIC-1) levels are elevated in some inflammatory conditions and cancers.	28835660
Stomach Carcinoma	Altered Intercellular Communication	The prognostic significance of inflammation-based markers in patients with recurrent gastric cancer.	28836056
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	Masked hypertension (MHTN) and lack of nocturnal dipping in blood pressure (BP) have been linked to the state of inflammation.	28836174
Inflammation, Hypoalbuminemia, Failure (biologic function)	Altered Intercellular Communication	Early and persistent systemic inflammation and high NPWT output were associated with hypoalbuminemia, which was an independent predictor of failure to achieve PFC.	28837537
Communicable Diseases, Inflammation, Immune System Diseases, GDC Comorbidity Terminology	Altered Intercellular Communication	Elderly long-term care residents often exhibit a myriad of risk factors for immune dysfunction, including chronic inflammation and multiple comorbid conditions, which undoubtedly contribute to their enhanced susceptibility to infection.	28838148
Inflammation, Carcinoma of lung, Neoplasms	Altered Intercellular Communication	High neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are markers of host inflammation and associated with worse overall survival (OS) in several tumor types, but have not been analysed extensively in lung cancer in the era of immunotherapy.	28838390
vascular inflammations, Vasospasm	Altered Intercellular Communication	In conclusion, our results suggest that EPA and DHA pretreatment may be beneficial to counteract graft vasospasm and vascular inflammation in SV which are important factors in graft failure development.	28838848
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation is suggested to be a central feature of atherosclerosis, particularly among smokers.	28838917
Inflammation	Altered Intercellular Communication	Acute and chronic exposure to tobacco smoking is associated with inflammation, as quantified by both GlycA and high-sensitivity C-reactive protein.	28838917
Inflammation	Altered Intercellular Communication	This indicates that work stress is associated altered metabolic profile, increased systemic inflammation, and, in men, poorer liver function, which is a marker of high alcohol consumption.	28839130
Inflammation	Altered Intercellular Communication	Ultrapure dialysis water obtained with additional ultrafilter may reduce inflammation in patients on hemodialysis.	28840494
Inflammation, Anemia, Atherosclerosis	Altered Intercellular Communication	Inflammation is a potent trigger of atherosclerosis and a pathogenetic factor in anemia, increasing mortality and morbidity in dialysis patients.	28840494
Bronchitis	Altered Intercellular Communication	Asthma is a syndrome of chronic bronchial inflammation and airway remodelling.	28840844
Inflammation, Tumor necrosis	Altered Intercellular Communication	Nuclear factor-kappa B dimers are encoded by nuclear factor-kappa B genes and regulate transcription of several crucial proteins of inflammation such as tumour necrosis factor-alpha.	28840846
Inflammation, Impaired cognition	Altered Intercellular Communication	Evidence indicates that alcohol binges induce peripheral inflammation and an exacerbated neuroimmune response that may participate in alcohol-induced cognitive/behavioral dysfunctions.	28840951
Inflammation, Thrombosis, Injury of cardiac valve, Platelet aggregation test result	Altered Intercellular Communication	Platelet aggregation, thrombosis formation, and inflammation are the main causes of cardiac injury during PCI.	28841229
Inflammation, Blood Coagulation Disorders	Altered Intercellular Communication	Biomarkers of coagulopathy and inflammation, platelet counts, FDP, PT, a2-PI, AT III, plasminogen, and C-reactive protein were significantly different between the two groups.	28841902
Sepsis, Inflammation, Observation Method - Coagulation, Kidney Failure, Acute	Altered Intercellular Communication	Particularly, sTM was an independent predictive biomarker for the development of AKI that outperformed other coagulation and inflammation biomarkers as well as organ function in patients with sepsis.	28841902
Pain Distress Question, Hyperplastic Polyp, Inflammation	Altered Intercellular Communication	No difference in the proportion of patients with moderate/severe pain was found between MP/placebo groups at 24 hours (67% and 74%, kh2 = .2, P = .63, odds ratio = .7, 95% confidence interval = .2-2.8) or at 48 hours (57% and 68%, kh2 = .5, P = .46, odds ratio = .6, 95% confidence interval = .2-2.3), and no difference between groups in postoperative sensitization was found (P > .4) despite reduced preoperative intra-articular inflammation (IL-6) in the MP group versus placebo (median change in IL-6 = -70 pg/mL, interquartile range = -466 to 0 vs. 32 pg/mL, interquartile range = -26 to 75, P = .029).	28842370
Inflammation, DGCR2 gene	Altered Intercellular Communication	However, whether inflammatory stimuli activate TonEBP in NP cells and whether TonEBP controls inflammation during IDD is unknown.	28842479
Inflammation	Altered Intercellular Communication	Transcription factor NFkB is a major regulatory component influencing mucosal inflammation.	28842689
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Taken together, decreased expression of TNFAIP3 and its partners contribute to inflammation and up-regulation of apoptosis inhibitors that may create microenvironment for colorectal cancer.	28842689
Inflammation, Dislocations	Altered Intercellular Communication	The analysis consisted of determining whether the LHB was present, the extrinsic tendon abnormalities (dislocation, tendon coverage) and intrinsic abnormalities (fraying, inflammation, degeneration).	28842745
ARCN1 gene, Inflammation, Arterial Stiffness, Heart failure	Altered Intercellular Communication	In COPD patients, heart failure (HF) is associated with worse conditions such as inflammation, arterial stiffness, and increased risk mortality.	28844547
ARCN1 gene, Chronic Obstructive Airway Disease, Airway Obstruction	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory condition characterized by complex lesions of the lungs and other organs as well as a progressive obstruction of the airway.	28844547
Toxic effect	Altered Intercellular Communication	It was suggested an inflammation-derived oxidative stress and cytokine-dependent toxicity role in the nigrostriatal pathway degeneration and hasten progression of disease.	28844731
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease.	28845751
Airway structure, Asthma	Altered Intercellular Communication	Fractional exhaled nitric oxide (FeNO) is a non-invasive method used to reveal the eosinophilic inflammation of airway and to diagnose and manage asthma.	28846444
Tumor necrosis, Diabetes Mellitus	Altered Intercellular Communication	Interleukin 6 (IL-6) and Tumor Necrosis Factor a (TNF-a) Single Nucleotide Polymorphisms (SNPs), Inflammation and Metabolism in Gestational Diabetes Mellitus in Inner Mongolia.	28846666
Gestational Diabetes, Inflammation	Altered Intercellular Communication	CONCLUSIONS TNF-a -857C/T SNP, hs-CRP, IL-6, IL-8, and IL-6/IL-10 were associated with GDM in women from Inner Mongolia, as was serious inflammation and disordered lipid and glucose metabolisms.	28846666
Inflammation, Premature Obstetric Labor	Altered Intercellular Communication	Decidual senescence has been considered a mechanism of disease for spontaneous preterm labor in the absence of severe acute inflammation.	28847437
Cerebrovascular Disorders, Arteritis	Altered Intercellular Communication	Increasing data supports the role of bacterial inflammation in adverse events of cardiovascular and cerebrovascular diseases.	28847664
Communicable Diseases, Inflammation, Bacterial Infections, CRNKL1 wt Allele	Altered Intercellular Communication	Patients with ACLF and bacterial infections (either at diagnosis or during follow-up) showed higher grade of systemic inflammation at diagnosis of the syndrome, worse clinical course (ACLF 2-3 at final assessment: 47% vs 26%; p<0.001) and lower 90-day probability of survival (49% vs 72.5%;p<0.001) than patients with ACLF without infection.	28847867
Inflammation	Altered Intercellular Communication	They are severe and associated with intense systemic inflammation, poor clinical course and high mortality.	28847867
Chronic sinusitis	Altered Intercellular Communication	Lower Airway Inflammation in Eosinophilic Chronic Rhinosinusitis as Determined by Exhaled Nitric Oxide.	28848094
Airway structure, Craniosynostosis	Altered Intercellular Communication	ECRS patients had lower airway inflammation as revealed by an elevated FeNO, which was parallel to the Lund-Mackay CT scores.	28848094
Inflammation, Traumatic injury, Alcohol-Induced Disorders	Altered Intercellular Communication	Alcohol-induced immune-suppression during acute inflammation (trauma) was linked to nuclear factor-kappaB (NF-kB).	28848184
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	The definition of new markers of local and systemic inflammation of chronic obstructive pulmonary disease (COPD) is one of the priority directions in the study of pathogenesis and diagnostic methods improvement for this disease.	28848245
ARCN1 gene, Inflammation	Altered Intercellular Communication	The findings suggest a pathogenetic role of the investigated soluble molecules of the COPD development and allow considering the content of sCD8, sCD25, and sHLA-I-CD8 molecules as additional novel systemic and endobronchial markers of the progression of chronic inflammation of this disease.	28848245
Inflammation, ovarian neoplasm, Ascites	Altered Intercellular Communication	Markers of Oxidative Stress and Inflammation in Ascites and Plasma in Patients with Platinum-Sensitive, Platinum-Resistant, and Platinum-Refractory Epithelial Ovarian Cancer.	28848618
Inflammation, Ascites, Platinum-Sensitive Ovarian Carcinoma, Platinum-Resistant Ovarian Carcinoma	Altered Intercellular Communication	To determine the behavior of markers of oxidative stress and inflammation in plasma and ascites fluid in patients with platinum-sensitive, platinum-resistant, and platinum-refractory EOC.	28848618
Have Autoimmune or Inflammatory Condition, Connective Tissue Diseases, Immune System Diseases, Lupus Erythematosus	Altered Intercellular Communication	Systemic lupus erythematosus is a connective tissue disease characterized by autoimmune inflammation, which leads to specific and nonspecific immune disorders with the formation of various autoantibodies by activated B cells.	28849060
Traumatic injury	Altered Intercellular Communication	The present study confirmed the high expression of miR-24 in peripheral blood during AP, suggesting that miR-24 might have an intercellular communication role contributing to the AP-associated distant organ injury.	28849189
Inflammation	Altered Intercellular Communication	Disadvantaged social statuses, such as being female, poor, or a minority, are associated with increased psychosocial stress and elevated circulating concentrations of C-reactive protein, a biomarker of chronic inflammation and indicator of cardiovascular health.	28849408
Inflammation, Osteoporosis, Joint structure of shoulder region, Fracture, Arthritis	Altered Intercellular Communication	Exclusion criteria were: glenohumeral arthritis or other inflammation, fracture around the shoulder joint, elderly patients with osteoporosis.	28850207
Inflammation	Altered Intercellular Communication	The long-term gastric inflammation and associated-damage to the gastric mucosa might play a role in such associations.	28850590
Heart failure	Altered Intercellular Communication	We observed a response of advanced heart failure patients to surgery orchestrated into stages: first, activation of the innate immune response, followed by anti-inflammation, and finally reparative processes such as mitosis, coagulation, and apoptosis.	28851355
Inflammation, Lipids abnormal	Altered Intercellular Communication	The results of proteomic analysis were consistent with involvement of inflammation, lipid abnormalities, hemostasis and extracellular matrix remodeling in CAS.	28851525
Sarcoma, Inflammation	Altered Intercellular Communication	The presence of systemic inflammation has been reported to be associated with poor prognosis in patients with soft tissue sarcoma (STS).	28851899
Degenerative polyarthritis, Pain Distress Question, Inflammation, malvidin	Altered Intercellular Communication	Malvidin attenuates pain and inflammation in rats with osteoarthritis by suppressing NF-kB signaling pathway.	28852776
Pain Distress Question, Inflammation	Altered Intercellular Communication	Our findings suggest that Malvidin significantly attenuates the OA-induced pain and inflammation by inhibiting NF-kB signaling pathway and suppressing pro-inflammatory cytokine expression and chondrocyte apoptosis.	28852776
Inflammation	Altered Intercellular Communication	However, since the mesh is placed in close contact with the spermatic cord, mesh-induced inflammation may affect its structures, possibly resulting in impaired fertility.	28852860
Liver carcinoma	Altered Intercellular Communication	The preoperative globulin-to-albumin ratio, a novel inflammation-based prognostic system, predicts survival after potentially curative liver resection for patients with hepatocellular carcinoma.	28853157
Inflammation, Structure of pectineus muscle	Altered Intercellular Communication	Follow-up MRI at two weeks demonstrated a dramatic reduction in the inflammation of the pectineus.	28853599
Communicable Diseases, Inflammation, Abnormal degeneration, Laceration	Altered Intercellular Communication	In this setting, chronic inflammation and lacerations associated with history of human papillomavirus (HPV) infection may induce a high risk of malignant degeneration in the long term.	28853678
Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	Inflammation in the tumour microenvironment mediated by interleukin 1b is hypothesised to have a major role in cancer invasiveness, progression, and metastases.	28855077
Inflammation, Malignant Head and Neck Neoplasm, Atherosclerosis	Altered Intercellular Communication	Human papillomavirus (HPV) is found in nearly half of head and neck cancers and is associated with inflammation and atherosclerosis.	28855164
Hypogonadism, Osteopenia, Fracture	Altered Intercellular Communication	Although hypogonadism is a risk factor for bone loss and fractures, the different etiopathophysiology and hormonal profile of classical and obesity-induced hypogonadism may lead to differences in musculoskeletal profile.	28856390
ARCN1 gene, Inflammation, Cardiovascular Diseases, Chronic Obstructive Airway Disease, Endothelial dysfunction, Arterial Stiffness	Altered Intercellular Communication	Chronic obstructive pulmonary disease (COPD) is associated with endothelial dysfunction, arterial stiffness and systemic inflammation, which are linked to increased cardiovascular disease risk.	28857336
Arterial Stiffness, Inflammation, Dyspnea, ARCN1 gene	Altered Intercellular Communication	Eight weeks of periodized aerobic training did not improve endothelial function, arterial stiffness or systemic inflammation in COPD, despite improvements in aerobic capacity, blood pressure and dyspnoea.	28857336
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Dietary elimination can improve symptoms and endoscopic inflammation in patients with IBD.	28858071
Kallmann Syndrome, Anosmia, Sense of smell impaired	Altered Intercellular Communication	Kallmann syndrome (KS) is a genetic gonadotropin-releasing hormone deficiency associated with hyposmia or anosmia and characterized by various modes of inheritance.	28858133
glycation, vascular inflammations, Endothelial dysfunction	Altered Intercellular Communication	Amyloidogenic medin induces endothelial dysfunction and vascular inflammation through the receptor for advanced glycation endproducts.	28859297
Inflammation	Altered Intercellular Communication	These patients, despite having no signs of significant inflammation, report an impact of disease similar to the non-remission patients.	28859325
Inflammation	Altered Intercellular Communication	Colchicine introduction and dose increase lead to significant reduction of clinical symptoms and inflammation.	28859329
Inflammation	Altered Intercellular Communication	Small proline-rich proteins (SPRR) are polypeptides that have recently been shown to contribute to epithelial biomechanical properties relevant in T-helper type 2 inflammation.	28859701
Inflammation, Arthritis	Altered Intercellular Communication	Synovial inflammation plays a critical role in the symptoms and structural progression of arthritis which leads to irreversible damage of the adjacent cartilage and bone.	28860038
Inflammation, Asthma	Altered Intercellular Communication	Fraction of exhaled nitric oxide (FeNO) provides information about chronic inflammation in asthma.	28860527
Refractory anemias, Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Early intervention for controlling the inflammation associated with RA can play a significant role in preventing cardiac remodeling in ACS patients.	28860666
Inflammation, Impaired cognition	Altered Intercellular Communication	Furthermore, inflammation markers were significantly correlated with muscle strength, walking distance and cognitive impairment.	28860729
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Higher values of IP-10 were associated with increasing stages of fibrosis (P<0.01) and higher grades of inflammation (P=0.02, P=0.07) assessed morphologically and noninvasively through FibroTest and ActiTest.	28862188
Inflammation, Aggressive behavior	Altered Intercellular Communication	The odontogenic keratocyst is known for its aggressiveness, high recurrence rate, and transformation of keratinized epithelia to nonkeratinized squamous epithelium for which inflammation has been suggested to be responsible.	28862228
Acromegaly	Altered Intercellular Communication	Reoperation for recurrent acromegaly has been associated with poor results, with hormonal control usually achieved in fewer than 50% of cases.	28862548
Inflammation, Aggressive behavior	Altered Intercellular Communication	These results indicate that low serum albumin levels correlate with increased parameter measures of HCC aggressiveness, in addition to their role as a monitor of systemic inflammation.	28862714
Kidney Failure, Chronic, Inflammation, Malnutrition	Altered Intercellular Communication	Sedentariness, high inflammation status and malnutrition are highly prevalent in end-stage kidney disease patients on maintenance hemodialysis (MHD).	28862722
Inflammation	Altered Intercellular Communication	Greater physical activity assessed by PAEE was associated with indicators of better nutritional and inflammation status.	28862722
Myocarditis	Altered Intercellular Communication	Multiple Cox regression analysis revealed perforin above the calculated cutoff point of 2.9 cells/mm2 as a strong predictor of impaired survival with a hazard ratio of 1.881 (95% confidence interval, 1.177-3.008; P=0.008), independent of left ventricular function and other myocardial inflammation markers (CD3, macrophage-1 antigen, leukocyte function-associated antigen-1, human leukocyte antigen-1, and intercellular cell adhesion molecule-1).	28862949
Plasmodium knowlesi, Inflammation, Malaria, Falciparum, physiopathological	Altered Intercellular Communication	Effects of Aging on Parasite Biomass, Inflammation, Endothelial Activation, Microvascular Dysfunction and Disease Severity in Plasmodium knowlesi and Plasmodium falciparum Malaria.	28863470
Tissue damage, Inflammation	Altered Intercellular Communication	NETosis is a host defense mechanism associated with inflammation and tissue damage.	28863968
Cerebral Amyloid Angiopathy, Vasculitis, Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	In amyloid b-related angiitis of the central nervous system (also called cerebral amyloid angiopathy-related inflammation), cerebral amyloid angiopathy occurs in association with primary vasculitis of small- and medium-sized leptomeningeal and cortical arteries.	28864038
Cerebral Amyloid Angiopathy, Inflammation, Hyperintensity of cerebral white matter on MRI	Altered Intercellular Communication	To avoid brain biopsy, clinicoradiological criteria (including clinical features due to inflammation-related uni/multifocal white matter hyperintensities) for the diagnosis of cerebral amyloid angiopathy-related inflammation have been validated recently.	28864038
Cerebral Amyloid Angiopathy	Altered Intercellular Communication	We report 3 cases with acute symptoms directly related to cerebral amyloid angiopathy in the presence of asymptomatic cerebral amyloid angiopathy-related inflammation hyperintensities on initial magnetic resonance imaging.	28864038
Cerebral Amyloid Angiopathy, Inflammation	Altered Intercellular Communication	Recognizing radiological features of cerebral amyloid angiopathy-related inflammation in patients with cerebral amyloid angiopathy is important because radiological isolated cerebral amyloid angiopathy-related inflammation may become symptomatic and immunosuppressive treatment is often effective in cerebral amyloid angiopathy-related inflammation, although optimal treatment regimen is yet unknown.	28864038
ARCN1 gene, Inflammation, Bronchiolitis	Altered Intercellular Communication	MicroRNA-218 acts by repressing TNFR1-mediated activation of NF-kB, which is involved in MUC5AC hyper-production and inflammation in smoking-induced bronchiolitis of COPD.	28864214
ARCN1 gene, Inflammation	Altered Intercellular Communication	As determined in the present investigation, population-based data indicate that smokers with COPD had serious airflow obstruction and inflammation, whereas smokers without COPD had mild airflow obstruction and inflammation.	28864214
ARCN1 gene, Inflammation, Bronchiolitis	Altered Intercellular Communication	In sum, our findings provide a mechanism by which miR-218 regulates CSE-induced MUC5AC hyper-production and inflammation by targeting TNFR1-mediated activation of NF-kB, indicating that overexpression of miR-218 may be a strategy against cigarette smoking-induced bronchiolitis in COPD.	28864214
Inflammation	Altered Intercellular Communication	Although high ferritin levels are associated with iron overload, it is known that ferritin is also an acute-phase reactant that may be elevated in conditions associated with acute and chronic inflammation.	28864373
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	These findings suggest that synovial inflammation is likely the result of joint structural abnormalities in established OA.	28864651
Communicable Diseases, Inflammation, Injury of integument	Altered Intercellular Communication	Skin injury affects millions of people via the uncontrolled inflammation and infection.	28864782
Inflammation, Autonomic nervous system disorders, Brain Damage, Chronic	Altered Intercellular Communication	Although correlations were weak and not significant, pupillary autonomic dysfunction is rather linked to chronic damage than to active inflammation or symptoms of autonomic dysfunction.	28864843
Inflammation, Esophageal Diseases, "Extra-osseous Ewings sarcoma	Altered Intercellular Communication	EoE was defined as the presence of symptoms of esophageal dysfunction with pathologically proven eosinophilic inflammation (>=15 eosinophils per high-power field [EOS/HPF]) unresponsive to reflux therapy.	28865084
Inflammation, Experimental Autoimmune Encephalomyelitis, MS gene	Altered Intercellular Communication	In multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), inflammation is perpetuated by both infiltrating leukocytes and astrocytes.	28865458
Respiratory Distress Syndrome, Adult, Inflammation	Altered Intercellular Communication	In addition, extracellular histones correlated with an evident systemic inflammation detected in ARDS patients.	28865478
Respiratory Distress Syndrome, Adult, Inflammation, Liver damage	Altered Intercellular Communication	Extracellular histones in ARDS patients are excessively increased and may contribute to disease aggravation by inducing cellular damage and promoting systemic inflammation.	28865478
Carcinogenesis, Gastrointestinal inflammation	Altered Intercellular Communication	Dietary patterns affect systemic and local intestinal inflammation, which have been linked to colorectal carcinogenesis.	28865736
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	These findings suggest that diet-related inflammation might contribute to development of colorectal cancer, by suppressing the adaptive anti-tumor immune response.	28865736
Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	There has been conflicting results regarding the role of ferritin, a nonspecific marker of systemic inflammation, in the development of coronary heart disease (CHD).	28865891
Inflammation	Altered Intercellular Communication	The mechanisms may be attributed to immune suppression-triggered infection or immune overreaction-triggered aseptic inflammation.	28866066
Allergic sensitization, Inflammation, Asthma	Altered Intercellular Communication	With advancing age, patients with severe asthma are more obese, have greater airflow limitation, less allergen sensitization, and variable type 2 inflammation.	28866107
palladium, Inflammation, Intestinal infectious disease (disorder)	Altered Intercellular Communication	We explore the possibility that intestinal infections, and associated inflammation, place individuals at increased risk of PD by increasing alpha-synuclein levels and promoting the formation of alpha-synuclein aggregates that propagate in a prion-like fashion via the vagal nerve to the brainstem.	28866688
Inflammation, Electrocardiogram: myocardial infarction (finding), myocardial injury	Altered Intercellular Communication	Frequency of Cholesterol Crystals in Culprit Coronary Artery Aspirate During Acute Myocardial Infarction and Their Relation to Inflammation and Myocardial Injury.	28867129
Rupture, Inflammation	Altered Intercellular Communication	Cholesterol crystals (CCs) have been associated with plaque rupture through mechanical injury and inflammation.	28867129
Acute myocardial infarction, Inflammation, myocardial injury	Altered Intercellular Communication	This study evaluated the presence of CCs during acute myocardial infarction (AMI) and associated myocardial injury, inflammation, and arterial blood flow before and after percutaneous coronary intervention.	28867129
Communicable Diseases, Inflammation, Depression, CTCAE	Altered Intercellular Communication	High serum albumin levels may provide protection against depression through its defensive role in inflammation and infection.	28867422
Inflammation	Altered Intercellular Communication	Accumulation of large-scale mitochondrial DNA (mtDNA) deletions and chronic, subclinical inflammation are concomitant during skin aging, thus raising the question of a causal link.	28867657
Dermatitis	Altered Intercellular Communication	Mice displayed low amounts of large-scale deletions and a dramatic depletion of mtDNA in the epidermis and showed macroscopic signs of severe skin inflammation.	28867657
Respiratory chain dysfunction, Inflammation	Altered Intercellular Communication	Altogether, these data unraveled a previously unknown link between an imbalanced stoichiometry of the mitochondrial respiratory chain complexes and skin inflammation and suggest that severe respiratory chain dysfunction, as observed in few cells leading to a mosaic in aged tissues, might be involved in the development of chronic subclinical inflammation.	28867657
Data types - Address	Altered Intercellular Communication	Inflammation-related markers were associated with age, but not AD.	28869479
ACSM3 gene, Inflammation, Brain Injuries	Altered Intercellular Communication	Early brain injury (EBI) plays an important role in the pathophysiology of SAH, and inflammation is a major contributor to EBI.	28869993
ACSM3 gene, Inflammation	Altered Intercellular Communication	Inflammation is a widely studied topic in both experimental and clinical conditions; however, just a few clinical studies have focused primarily on the early inflammatory response after SAH, and detailed information about the association between the dynamics of early inflammatory response with main clinical characteristics is lacking.	28869993
Inflammation, Obesity	Altered Intercellular Communication	Understanding the extent to which visceral and subcutaneous body fat are associated with markers of nutrition and inflammation in patients on dialysis therapy could shed light on the obesity paradox and the biology of subcutaneous fat.	28870376
Inflammation	Altered Intercellular Communication	Subcutaneous fat may be an indicator of nutritional status, and visceral fat, an indicator of inflammation.	28870376
Peripheral Nervous System Diseases	Altered Intercellular Communication	To identify potential master switches in the neuro-immune balance, we aimed at characterizing inflammation-regulating miRNA profiles in patients with peripheral neuropathies.	28870579
Inflammation	Altered Intercellular Communication	The pleiotropic cytokine interleukin (IL)-10 is best characterized by its ability to downregulate inflammation and promote peripheral tolerance.	28870600
Inflammation, Diffuse Large B-Cell Lymphoma	Altered Intercellular Communication	Together, these results suggested that IL-10 could enhance CD8+ T cell inflammation in DLBCL patients.	28870600
Inflammation	Altered Intercellular Communication	KS lesions are driven by pathological angiogenesis, chronic inflammation, and oncogenesis, and various in vitro cell culture models have been developed to study these processes.	28872106
Inflammation, Structure of parenchyma of lung, Fatigue	Altered Intercellular Communication	This model demonstrated the following: 1) decreased forced expiratory volume 25, 50, and 75/forced vital capacity (FEV25/FVC, FEV50/FVC, and FEV75/FVC), indicating the deterioration of lung function; 2) enlarged lung alveoli, with lung parenchymal destruction; 3) reduced fatigue time and distance; and 4) increased inflammation.	28872147
Atherosclerosis, Inflammatory disorder, Cerebrovascular accident	Altered Intercellular Communication	BACKGROUND CCL11 is an important inflammatory cytokine associated with inflammation-related diseases such as atherosclerosis and stroke.	28873081
Sleep-Disordered Breathing, Impaired cognition, physiopathological, Hyperexcitability Behavior	Altered Intercellular Communication	These findings are interpreted in terms of a pathophysiological model of SDB in which hypoxia-mediated inhibitory neurotransmission deficit in DLPFC could lead to hyperexcitability and, potentially neuronal dysfunction and cognitive decline.	28874569
Inflammatory disorder	Altered Intercellular Communication	Evidence for a link between platelets indices and inflammation disease comes from recent studies.	28874620
Parkinson Disease, Restless Legs Syndrome	Altered Intercellular Communication	Restless legs syndrome in Parkinson disease: Clinical characteristics, abnormal iron metabolism and altered neurotransmitters.	28874701
Parkinson Disease, palladium, Restless Legs Syndrome	Altered Intercellular Communication	Relationships among clinical characteristics, iron metabolism and neurotransmitters in Parkinson disease (PD) patients with restless legs syndrome (RLS) remains unclear.	28874701
Glioblastoma Multiforme Pathway	Altered Intercellular Communication	Gap-junctional intercellular communication (GJIC) plays a major role in the malignant growth of glioma.	28875331
Inflammation	Altered Intercellular Communication	In addition, this report describes how to discriminate inflammation between SS and periprosthetic joint infection.	28875344
Inflammation	Altered Intercellular Communication	Subclinical inflammation that persists during attack-free periods can result in oxidative stress (OS) damage.	28875601
Inflammation	Altered Intercellular Communication	PFD may reduce the inflammation in AE-IP patients undergoing corticosteroid treatment.	28876508
Inflammation, Fibrosis Assessment, Granuloma	Altered Intercellular Communication	A semiquantatitive grading system was used to assess extent of fibroblastic foci, intra-alveolar fibroelastosis, visceral pleural fibrosis, chronic inflammation in areas of fibrosis, vascular fibrointimal thickening, and presence of granulomas.	28877057
Inflammation, Fibrosis Assessment, Granuloma	Altered Intercellular Communication	All biopsies showed intra-alveolar fibroelastosis, fibroblastic foci at the leading edge of fibrosis and chronic inflammation within areas of fibrosis, 91% showed vascular fibrointimal thickening of vessels, 73% showed pleural fibrosis, and 35% showed granulomas.	28877057
NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology, Respiratory Insufficiency	Altered Intercellular Communication	Myelodysplastic syndrome patients present more severe respiratory muscle impairment and reduced forced vital capacity: Is disordered inflammatory signaling the culprit?	28877261
Pain Distress Question, Inflammation	Altered Intercellular Communication	Physical examination showed a small expansion and redness of the right mandibular buccal and lingual cortical plates, but no signs of pain or inflammation were observed.	28877285
Inflammation	Altered Intercellular Communication	There is accumulating evidence that diet may be associated with markers of inflammation.	28877589
Inflammation	Altered Intercellular Communication	We have evaluated if an empirically developed questionnaire-based Anti-Inflammatory Diet Index (AIDI) may predict low-grade systemic chronic inflammation in a Nordic population.	28877589
Inflammation	Altered Intercellular Communication	Our results lead to the hypothesis that the empirically developed questionnaire-based dietary anti-inflammatory index may predict low-grade systemic inflammation.	28877589
Inflammation, Respiratory Hypersensitivity, mucus secretion	Altered Intercellular Communication	Knockin mice analogous to the human R213G SNP had lower airway hyperresponsiveness, inflammation, and mucus hypersecretion with decreased interleukin-33 (IL-33) in bronchoalveolar lavage fluid and reduced type II innate lymphoid cells (ILC2s) in lungs.	28878123
Inflammation, Ulcer	Altered Intercellular Communication	In this study, we assess the expression levels of OPN in chronic wounds to assess its potential contribution to the exacerbated inflammation seen in chronic ulcers, which is thought to contribute to poor healing.	28880752
Inflammation	Altered Intercellular Communication	This study provides strong histopathologic evidence that OPN expression is significantly increased in chronic wounds, suggesting that its upregulation could contribute to the exacerbated inflammation.	28880752
Inflammation, Virus Diseases	Altered Intercellular Communication	This is the first report of a human pathogenic ELANE mutation associated with a defect in NETosis and a distinct syndrome of recurrent viral infection and chronic inflammation.	28881492
Inflammation, Plasmacytosis	Altered Intercellular Communication	These observations highlight the need for IgG4 immunohistochemical staining of esophageal biopsies especially in patients with mucosal ulceration, chronic inflammation, and plasmacytosis on biopsy.	28881885
septic	Altered Intercellular Communication	C-reactive protein to albumin (CRP/Alb) ratio, a novel inflammation-based prognostic score, was first developed as a prognostic score for septic patients.	28881893
Acute Kidney Injury, CTCAE, Inflammation, Kidney Failure, Acute	Altered Intercellular Communication	Inflammation plays an important role in the initiation and progression of acute kidney injury (AKI).	28882170
Carcinogenic Chlorinated Hydrocarbon, Inflammation	Altered Intercellular Communication	We asked whether the presence of DM affects endothelial-derived (EMPs) and platelet-derived microparticles (PMPs) levels; and whether MPs levels associate with biomarkers of inflammation and oxidative stress in patients with CHC.	28882977
Carcinogenic Chlorinated Hydrocarbon, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	We report a hitherto undescribed relationship between diabetes prevalence and apoptotic MPs-associated inflammation in patients with CHC.	28882977
Inflammation, Resolvin	Altered Intercellular Communication	Resolvins are omega-3 fatty acid derived potent bioactive lipids that resolve inflammation and modulate transient receptor potential channels.	28883634
Inflammation	Altered Intercellular Communication	These data highlight inflammation as a potentially important biological mechanism linking actor reports of life satisfaction to lower cardiovascular mortality.	28884245
Inflammation, Stomach Carcinoma, Cytomegalovirus Infections	Altered Intercellular Communication	We suggest the possibility that the addition of chronic inflammation of CMV infection to H. pylori-induced gastritis facilitated the development of gastric cancer.	28884453
Inflammation, Venous Injury, CTCAE	Altered Intercellular Communication	Using multivariate regression analysis, periarterial inflammation had significant association with major venous injury (P < 0.001).	28887236
Inflammation, Failure (biologic function)	Altered Intercellular Communication	The mechanisms underpinning the failure of inflammation to resolve in diseased musculoskeletal soft tissues are unknown.	28887458
Inflammation, SCAPULOPERONEAL MYOPATHY, X-LINKED DOMINANT	Altered Intercellular Communication	Taken together these results suggest that chronic inflammation in musculoskeletal soft tissues may result from dysregulated LM-SPM production, and that inhibition of 15-PGDH activity together with promoting resolution using SPM represents a novel therapeutic strategy to resolve chronic tendon inflammation.	28887458
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Treatment of chronic HCV with modern DAA therapy was associated with a significant improvement in LSM by VCTE measurement, suggesting possible early improvement in liver fibrosis along with resolution of inflammation over the first year after treatment completion.	28887750
Inflammation, Thrombosis, Pulmonary Embolism, Venous Thromboembolism, Influenza-like symptoms, Deep thrombophlebitis, vinyltriethoxysilane	Altered Intercellular Communication	Influenza-like illness and inflammation are known risk factors for venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and pulmonary embolism (PE).	28888342
Inflammation, Neoplasms	Altered Intercellular Communication	Inflammation plays a crucial role in tumor progression.	28888400
Blepharitis	Altered Intercellular Communication	Eyelid inflammation: An uncommon cause in occidental countries.	28888529
Inflammation, Hydropneumothorax, Fever, CTCAE	Altered Intercellular Communication	We present the atypical case of a 76-year-old man presenting with a hydro-pneumothorax, low-grade fever and elevated inflammation markers, after two complex percutaneous coronary interventions, executed 30 and 75 days prior.	28888531
Cartilage destruction, bone destruction, Pentalogy of Cantrell, Synovitis	Altered Intercellular Communication	In order to test the validity of the selected surgical technique as a way to manage persistent synovitis of the knee joint, as well as to slow down the cartilage and bone destruction, we studied the dynamics of biomarkers of inflammatory conditions, and bone and cartilage destruction after total arthroscopic synovectomy (TAS) of the knee joint.	28889180
Hepatic inflammation	Altered Intercellular Communication	Hepatic inflammation caused by dysregulated bile acid synthesis is reversible by butyrate supplementation.	28892150
Granulomatous inflammation, Granulomatous	Altered Intercellular Communication	Various patterns of granulomatous inflammation were observed including sarcoidal (31%), diffuse (25%), suppurative and granulomatous (25%), palisaded (13%) and lichenoid (6%).	28892183
Granulomatous inflammation, Leishmaniasis, Cutaneous	Altered Intercellular Communication	Multiple patterns of granulomatous inflammation occur in cutaneous leishmaniasis.	28892183
Inflammation	Altered Intercellular Communication	One subject withdrew voluntarily and one developed inflammation necessitating removal of the system.	28892221
Hyperandrogenemia, Inflammation, Hyperlipidemia, Cardiovascular Diseases, Atherosclerosis	Altered Intercellular Communication	Chronic inflammation, insulin resistance, hyperandrogenemia, hyperlipidemia and increased oxidative stress are known to have a role in the formation of atherosclerosis and cardiovascular disease.	28892255
vascular inflammations, Hypersensitivity	Altered Intercellular Communication	Localized vascular inflammation has been associated with endovascular nBCA use in histopathologic studies, but reports of systemic hypersensitivity reactions following endovascular embolization with nBCA are rare.	28893128
Airway structure, Exacerbation	Altered Intercellular Communication	This finding suggests that eosinophilic airway inflammation contributes to COPD exacerbations.	28893134
Inflammation, HIV Infections	Altered Intercellular Communication	We hypothesized that the chronic and persistent inflammation and immune activation associated with HIV disease leads to accelerated aging, characterized by CVD.	28893184
Degenerative polyarthritis	Altered Intercellular Communication	Hip Inflammation MRI Scoring System (HIMRISS) to predict response to hyaluronic acid injection in hip osteoarthritis.	28893678
Carcinoma of lung, Inflammation, Primary malignant neoplasm, Pulmonary Emphysema	Altered Intercellular Communication	Lipidomes of lung cancer and tumour-free lung tissues reveal distinct molecular signatures for cancer differentiation, age, inflammation, and pulmonary emphysema.	28894173
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Partial least squares regression showed correlations between lipid profiles of tumour-free alveolar tissues and the degree of emphysema, inflammation status, and the age of patients.	28894173
Inflammation, Calcinosis	Altered Intercellular Communication	Inflammation, calcification, and structural integrity were also assessed.	28895294
Inflammation, Blood Clot	Altered Intercellular Communication	Inflammation and thrombus in the valve frame was minimal, but neointimal growth increased overtime.	28895294
Bacterial Endocarditis	Altered Intercellular Communication	Inflammation of the leaflets was mild, while structural changes were minimal, and one case had infective endocarditis.	28895294
Inflammation, Dyslipidemias, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Relationship between Oxidative Stress, Inflammation and Dyslipidemia with Fatty Liver Index in Patients with Type 2 Diabetes Mellitus.	28895641
Inflammation, square decimeter, Dyslipidemias, Non-alcoholic Fatty Liver Disease, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Considering the high prevalence of non-alcoholic fatty liver disease (NAFLD) in individuals with type 2 diabetes mellitus (DM2), we aimed to investigate the potential benefit of determining markers of oxidative stress, inflammation and dyslipidemia for prediction of NAFLD, as estimated with fatty liver index (FLI) in individuals with DM2.	28895641
Inflammation, Dyslipidemias, Diabetes Mellitus, Fatty Liver Disease	Altered Intercellular Communication	Multimarker approach, including biomarkers of oxidative stress, dyslipidemia and inflammation, could be of benefit in identifying patients with diabetes being at high risk of fatty liver disease.	28895641
Trachoma	Altered Intercellular Communication	On Tarawa, the most populous Kiribati island, both the active trachoma sign "trachomatous inflammation-follicular" (TF) and TT are present at prevalences warranting intervention.	28898240
Alzheimers Disease", Tauopathies, Inflammation	Altered Intercellular Communication	(doi:10.1093/awx174) for a scientific commentary on this article.Sleep deprivation increases amyloid-b, suggesting that chronically disrupted sleep may promote amyloid plaques and other downstream Alzheimer's disease pathologies including tauopathy or inflammation.	28899014
Stomach Carcinoma	Altered Intercellular Communication	Prognostic value of systemic immune-inflammation index in patients with gastric cancer.	28899420
Primary malignant neoplasm	Altered Intercellular Communication	Inflammation-based indexes have been used to predict survival and recurrence in cancer patients.	28899420
Malignant Neoplasms	Altered Intercellular Communication	Systemic immune-inflammation index (SII) was reported to be associated with prognosis in some malignant tumors.	28899420
Solitary fibrous tumor, Meningitis	Altered Intercellular Communication	Although meningeal inflammation was infrequent in patients with SFTSAE, SFTS virus was frequently detected in CSF with elevated MCP-1 and IL-8.	28899841
Peritonsillar, Inflammation, Tonsillitis	Altered Intercellular Communication	We analysed the presence of peritonsillar minor salivary glands and inflammation patterns in 114 adult tonsils representing three patient groups: recurrent AT, chronic tonsillitis (CT), and PTA.	28900734
Peritonsillar, Inflammation	Altered Intercellular Communication	The majority of our 114 tonsillectomy specimens, collected from patients with AT, CT, or PTA, presented with infected minor salivary glands, and inflammation of the peritonsillar space glands was evident.	28900734
Inflammation, Hypoxia	Altered Intercellular Communication	However, the association between chronic inflammation and high blood pressure caused by hypoxia remains to be fully elucidated.	28901415
Inflammatory Bowel Diseases, Disturbance, Inflammation	Altered Intercellular Communication	Bidirectional Regulation of Circadian Disturbance and Inflammation in Inflammatory Bowel Disease.	28902123
Inflammatory Bowel Diseases, Disturbance, Inflammation	Altered Intercellular Communication	We hypothesized that circadian timekeeping was perturbed in inflammatory bowel disease (IBD), and that the bidirectional regulation of circadian disturbance and inflammation may be involved in the pathogenesis of IBD.	28902123
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Our results suggested that inflammation and circadian genes showed complex bidirectional regulations that were relevant to IBD.	28902123
Inflammation, Peri-Implantitis	Altered Intercellular Communication	Resective peri-implantitis surgery seemed to reduce the amount of peri-implant inflammation.	28902415
Inflammation, Hypersensitivity	Altered Intercellular Communication	Increased activity at the left deltoid region suggests a false-positive finding related to radiotracer sequestration due to inflammation from a localized postvaccination hypersensitivity reaction.	28902736
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Moreover, diet may influence inflammation as well as depression but no previous study examined whether inflammatory dietary patterns are related to depression in an older population.	28903062
Prostate carcinoma	Altered Intercellular Communication	Inflammation polymorphisms and prostate cancer risk in Jamaican men: Role of obesity/body size.	28903065
Inflammation, VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding), Pruritus	Altered Intercellular Communication	The multivariate analysis of factors associated with a high BMI (>=30) in vitiligo patients showed a significant association between a high BMI and a sudden onset of vitiligo (p = 0.021; OR = 3.83; 95% CI 1.22-11.99) and the presence of inflammation and pruritus (p = 0.031; OR = 3.26; 95% CI 1.11-9.57).	28903118
Inflammation, Specimen Type - Fistula	Altered Intercellular Communication	Because contact between the mesh and the cecum resulted in inflammation, a fistula formed in his bladder.	28903762
Inflammation, White matter lesions, Liver Dysfunction	Altered Intercellular Communication	The workup revealed brain white matter lesions, abnormal liver function tests and biological inflammation without evidence of Loa loa microfilariae in blood and cerebrospinal fluid.	28904727
Inflammation, Metabolic Syndrome X, Diabetes Mellitus, Renal Insufficiency, Chronic Kidney Diseases	Altered Intercellular Communication	Increased age, elevated fibrinogen, decreased albumin, diabetes mellitus, hyperTG, and worse virological control were risk factors for renal impairment.The HIV-positive patients in our area have a CKD prevalence of 4% to 5% (90% stage 3 CKD) associated with ageing, inflammation, worse immune control of HIV, TDF treatment, and metabolic syndrome.	28906351
Dental Plaque, Peri-Implantitis	Altered Intercellular Communication	While peri-implantitis represents a plaque-induced inflammatory condition, certain local factors might be associated with this biologic complication, as they imply plaque retention.	28906504
Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Adenoma of large intestine	Altered Intercellular Communication	Metabolic syndrome (MetS) is an important cardiovascular risk factor for insulin resistance and has been linked to colorectal adenoma via inflammation.	28910195
Trachoma	Altered Intercellular Communication	Surveys are needed to guide trachoma control efforts in Mozambique, with WHO guidelines for intervention based on the prevalence of trachomatous inflammation-follicular (TF) in children aged 1-9 years and the prevalence of trichiasis in adults aged 15 years and above.	28910562
ARCN1 gene, Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	These findings suggest a complex interaction between fat, inflammation, and emphysema that should be considered when phenotyping patients with COPD and provide new evidence of an inverse association between emphysema progression and chest subcutaneous fat.	28910816
Inflammation	Altered Intercellular Communication	The correlation between IL-6 and PAPP-A indicates that inflammation plays a role in promoting local tissue IGF activity.	28911149
Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Low-grade inflammation is involved in the development of type 2 diabetes and cardiovascular disease (CVD); however, prospective studies evaluating inflammatory markers as predictors of changes in insulin secretion and insulin sensitivity are lacking.	28911155
Inflammation	Altered Intercellular Communication	Thus, IL-37 may serve as a novel therapeutic target for the treatment of OA inflammation.	28912428
Mesenteric Lymphadenitis	Altered Intercellular Communication	What is Known: * Mesenteric adenitis is a self-limiting inflammatory condition with well-characterized clinical presentation and imaging features.	28913615
Inflammation, Obstruction, Adenocarcinoma of lung (disorder)	Altered Intercellular Communication	Here we report a patient with lung adenocarcinoma who was treated with nivolumab and developed obstruction because of biliary inflammation.	28913619
Inflammation	Altered Intercellular Communication	It is possible that regulatory cells in the immune system could function to suppress inflammation and possibly slow or reverse disease progression.	28913840
Inflammation, Acute postoperative pain	Altered Intercellular Communication	Preoperative ultraviolet B inflammation in skin: Modelling individual differences in acute postoperative pain and neuro-immune interactions.	28913854
Inflammation, Hyperalgesia	Altered Intercellular Communication	We conducted psychophysical and transcriptional analysis of hyperalgesia arising as a result of UVB-induced inflammation in patients before total knee arthroplasty (TKA, n = 23).	28913854
Inflammation, Pain, Postoperative	Altered Intercellular Communication	A simple model of UVB inflammation in the skin might predict the degree of a patient's neuro-immune response and the extent of their postoperative pain after total knee arthroplasty.	28913854
Refractory anemias, Inflammation, Primary malignant neoplasm, vinyltriethoxysilane	Altered Intercellular Communication	Thus, VTE may not only be a result of inflammation and immunological dysfunctions associated with RA, but may also be a marker for occult cancer.	28913891
Inflammation, Fibrosis Assessment, Lacrimal Duct Obstruction	Altered Intercellular Communication	Lacrimal sac mucosa and lumen were grossly inspected, and the frequency of lacrimal sac changes, such as significant inflammation or fibrosis, was analyzed in cases of CCO or canalicular obstruction.	28913995
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Of 253 cases with CCO, 122 (48.2%) showed clear lacrimal sac lumen, and the other 131 (51.8%) showed significant inflammation or fibrosis of the lacrimal sac.	28913995
Inflammation, Dental caries	Altered Intercellular Communication	Pulpotomy technique is most widely accepted clinical procedure for treating primary teeth with coronal pulp inflammation caused by caries with no involvement of the radicular pulp.	28914245
Inflammation, Atherosclerosis, Lupus Erythematosus, Systemic, Lupus Erythematosus	Altered Intercellular Communication	We evaluated the association of serum CysC with renal function, CV risk factors, inflammation, and subclinical atherosclerosis in Systemic Lupus Erythematosus (SLE) patients.	28914371
Inflammation	Altered Intercellular Communication	New evidence clarifying the correlation between ROS and inflammation has indicated that oxidative stress can up-regulate inflammatory cytokines.	28914997
Gingivitis, Inflammation, Periodontitis	Altered Intercellular Communication	Gingivitis, an inflammation of the gingival tissues, typically progresses to periodontitis.	28915302
Arthralgia, Inflammation, Arthritis	Altered Intercellular Communication	Absence of ultrasound inflammation in patients presenting with arthralgia rules out the development of arthritis.	28915847
MTA2 gene, Communicable Diseases, Ectopic Pregnancy, Pelvic Inflammatory Disease	Altered Intercellular Communication	C. trachomatis infection was associated with age, marital status, pregnancy, and hormonal contraceptive use (all p = 0.01); intrauterine device use and previous premature birth (both p = 0.03); and infection during pregnancy, previous ectopic pregnancy, pelvic inflammatory disease (PID), and green vaginal discharge (all p = 0.04).	28915869
Inflammation, Colorectal Carcinoma, Neoplasms	Altered Intercellular Communication	Given the importance of inflammation in CRC, we tested whether polymorphic variants in this gene could affect the risk of developing this neoplasia hypothesizing a role of TAS2R16 in modulating chronic inflammation within the gut.	28915899
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Ischaemia-reperfusion injury (IRI) causes inflammation, and diabetes is known to exacerbate this inflammatory response in the kidney, whereas alarmin IL-33 could act as an innate immune mediator during kidney IRI.	28916390
vascular inflammations	Altered Intercellular Communication	Small RNA-seq during acute maximal exercise reveal RNAs involved in vascular inflammation and cardiometabolic health: brief report.	28916639
Sepsis, vascular inflammations, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	Previous work revealed a strong role for miR-181b-5p in vascular inflammation in obesity, insulin resistance, sepsis, and cardiovascular disease.	28916639
Inflammation, diabetic, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Gene expression related to insulin, lipid and inflammation were quantified in peripheral blood mononuclear cells (PBMC) of diabetic patients with CHD with RT-PCR method.	28916975
Inflammation, Chronic Fatigue Syndrome, Depression, CTCAE	Altered Intercellular Communication	Depression, evening salivary cortisol and inflammation in chronic fatigue syndrome: A psychoneuroendocrinological structural regression model.	28918107
Inflammation, Chronic Fatigue Syndrome, Depression, CTCAE, physiopathological, Chronic disease	Altered Intercellular Communication	Since depression is known to be associated with HPA axis dysfunction and greater inflammation, a psychoneuroendocrinological (PNE) model of inflammation was examined in persons diagnosed with CFS in order to uncover underlying biopsychosocial mechanisms in this poorly understood chronic illness.	28918107
Inflammation, Tumor necrosis, Depression, CTCAE, Bipolar Disorder	Altered Intercellular Communication	Depression was directly related to evening salivary cortisol and inflammation, such that higher evening cortisol predicted greater depressive symptoms (b=0.215, p<0.01) and higher pro-inflammatory cytokines (interleukin-2 [IL-2], IL-6, and tumor necrosis factor-alpha [TNF-a] levels (b=0.185, p<0.05), when controlling for covariates.	28918107
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Results highlight the role of depression, cortisol and inflammation in possible biological mechanisms involved in the pathophysiology of CFS.	28918107
Inflammation, HIV Antigens	Altered Intercellular Communication	Systemic inflammation is a prognostic factor requiring validation in HIV-associated HCC.	28918424
Inflammation, Malignant Neoplasms, HIV Infections	Altered Intercellular Communication	Systemic inflammation, as measured by NLR, is a prognostic determinant associated with adverse pathological features of malignancy, but not coexisting HIV infection, suggesting a tumour-promoting role of the innate immune response that warrants further investigation in mechanistic studies.	28918424
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation has been reported to be involved in the pathogenesis of atherosclerosis.	28918492
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic Syndrome X, Cardiovascular Diseases	Altered Intercellular Communication	This principal objective of this study was to investigate if the secretion of neuregulin 4 (Nrg4), a soluble protein associated with metabolic syndrome and subclinical cardiovascular disease, is correlated with the inflammation marker high-sensitivity C-reactive protein (hs-CRP) in patients with newly diagnosed type 2 diabetes mellitus (nT2DM).	28918492
Liver carcinoma, Hepatitis, Neoplasms, FAM126A gene	Altered Intercellular Communication	Development of hepatocellular carcinoma (HCC) is associated with alterations in the transforming growth factor-beta (TGF-b) signaling pathway, which regulates liver inflammation and can have tumor suppressor or promoter activities.	28918914
Inflammation, Fibrosis Assessment, Neoplasms	Altered Intercellular Communication	These correlated with changes in expression of genes in the pathways; up-regulation of genes in this pathway would contribute to inflammation and fibrosis, whereas down-regulation would indicate loss of TGF-b tumor suppressor activity.	28918914
Inflammation, Damage	Altered Intercellular Communication	Inflammation in MS NAWM was characterized, compared to non immune-mediated conditions, by higher VCAM-1 expression, higher density of perivascular lymphocytes, focal perivascular inflammation with microglial expression of M1 markers, ongoing acute axonal damage correlating with VCAM-1 expression but not with microglia activation.	28919237
Wallerian Degeneration, Inflammation, Damage	Altered Intercellular Communication	Inflammatory changes in MS NAWM share all the main features observed in the WM in non immune-mediated conditions with wallerian axonal degeneration (with differences to a large extent more quantitative than qualitative), but with superimposition of disease-specific perivascular inflammation and ongoing acute axonal damage.	28919237
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	MMP-8 and TIMP-1 are associated to periodontal inflammation in patients with rheumatoid arthritis under methotrexate immunosuppression - First results of a cross-sectional study.	28919284
Inflammation, SMYD1 gene	Altered Intercellular Communication	Furthermore, higher blood concentrations of MMP-8 and tissue inhibitor of MMP (TIMP-1) were detected in patients with increased periodontal inflammation (BOP positive, p < 0.01).	28919284
Inflammation, "Crohns disease of the ileum	Altered Intercellular Communication	Computed tomography revealed segmental small bowel wall thickening with chronic inflammation suggestive of Crohn's ileitis and oral steroids were commenced; only later, ingestion of a foreign body was suspected.	28920530
Inflammation, Chronic disease	Altered Intercellular Communication	Evidence from the literature suggests that dietary flaxseed lignans have the ability to modulate inflammation, which is recognized as the underlying basis of multiple chronic human diseases in older adults.	28922068
Inflammation, Arteriopathic disease	Altered Intercellular Communication	The association between cigarette smoking and inflammation: The Genetic Epidemiology Network of Arteriopathy (GENOA) study.	28922371
Inflammation, Hypertension, CTCAE, Cardiovascular system	Altered Intercellular Communication	To inform the study and regulation of emerging tobacco products, we sought to identify sensitive biomarkers of tobacco-induced subclinical cardiovascular damage by testing the cross-sectional associations of smoking with 17 biomarkers of inflammation in 2,702 GENOA study participants belonging to sibships ascertained on the basis of hypertension.	28922371
Experimental Organism Luteinized Unruptured Follicle, Inflammation, Rupture, Aneurysm, Ruptured, Aneurysm	Altered Intercellular Communication	In conclusion, detection of thickened IEL, leaky vasa vasorum, and heavy inflammation as seen in ruptured IA in comparison to unruptured IA may identify aneurysms at risk of rupture, and management strategies preventing development of vasa vasorum or inflammation may reduce the risk of aneurysmal rupture.	28922850
Inflammation, Arteriopathic disease, Diabetes Mellitus	Altered Intercellular Communication	The mixture of shared with disparate determinants for arterial disease in the heart and the legs implies nonidentical pathogenesis: cholesterol dominant in the former, and inflammation (high-sensitivity C-reactive protein, diabetes mellitus, smoking) in the latter.	28923990
Seizures, Creutzfeldt-Jakob disease	Altered Intercellular Communication	Inhibition of IL-1b Signaling Normalizes NMDA-Dependent Neurotransmission and Reduces Seizure Susceptibility in a Mouse Model of Creutzfeldt-Jakob Disease.	28924012
Stable chronic Graft vs Host Disease, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Plasma levels of soluble factors associated with inflammation, fibrosis, and cGVHD significantly decreased over time with ibrutinib.	28924018
Inflammation, Fatty degeneration	Altered Intercellular Communication	Her liver sample showed marked improvement, especially in steatosis, inflammation, and ballooning.	28924123
Inflammation, Migraine Disorders	Altered Intercellular Communication	Based on this case, the pathophysiology of RPON may involve temporary nerve inflammation with migraine.	28924127
Vitreous inflammatory cells, Uveitis, Posterior, Uveitis	Altered Intercellular Communication	We report a new clinical sign of vitreous inflammation in patients with posterior uveitis: spectral-domain optical coherence tomography identified stalagmite-like, discrete, diffusely distributed, hyperreflective, preretinal deposits in previously vitrectomized eyes of 2 patients during flares of posterior uveitis.	28924415
Cardiac Hypertrophy, Chronic Kidney Diseases, Congestive heart failure	Altered Intercellular Communication	Elevated levels of fibroblast growth factor 23 (FGF23), a bone-derived phosphaturic hormone, are associated with a number of pathologic conditions including chronic kidney disease, cardiac hypertrophy, and congestive heart failure.	28924605
Inflammation, Malnutrition	Altered Intercellular Communication	IL-6 and sICAM-1 were independent preoperative prognostic factors in EHC patients, causing continuous inflammation and malnutrition in collaboration with other pro-angiogenic factors.	28925763
Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Atrial Fibrillation Ablation Increases Inflammation-Chemokine Modulation Suppresses Activation of Leukocytes Isolated after Ablation.	28925907
Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Atrial fibrillation (AF) ablation is associated with increased circulating markers of inflammation.	28925907
Inflammation, Cardiac Arrhythmia	Altered Intercellular Communication	Innate immune or inflammation pathways up-regulate mononuclear cell responses and may increase the risk for recurrent arrhythmia.	28925907
Communicable Diseases, Endophthalmitis, CTCAE, Inflammation	Altered Intercellular Communication	It is possible that some aspect of the infection, inflammation, or treatment of endophthalmitis had a disease-modifying impact on the eAMD.	28925926
Rheumatoid Arthritis, Inflammation, Atherosclerosis	Altered Intercellular Communication	Retinal vessel morphology in rheumatoid arthritis: Association with systemic inflammation, subclinical atherosclerosis, and cardiovascular risk.	28926162
Refractory anemias, Inflammation, Atherosclerosis	Altered Intercellular Communication	We examined retinal microvascular diameters in RA, particularly in regard to systemic inflammation, subclinical atherosclerosis, and cardiovascular risk.	28926162
Inflammation, Abnormality of the vasculature, Atherosclerosis	Altered Intercellular Communication	Inflammation appears as the biological link for the observed association between retinal microvascular abnormalities and subclinical atherosclerosis.	28926162
Hepatitis C, Neoplasms	Altered Intercellular Communication	On the other hand, the reduction of inflammation-triggered immune surveillance after very rapid elimination of the hepatitis C virus may have favored tumor progression.	28927498
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Astrocyte elevated gene-1 promotes inflammation and invasion of fibroblast-like synoviocytes in rheumatoid arthritis.	28927747
Refractory anemias, Inflammation	Altered Intercellular Communication	Collectively, Our findings provided evidence that AEG-1 contributed to the production of inflammatory cytokines, migration and invasion of RA FLS, and underscored the importance of AEG-1 in the inflammation process of RA.	28927747
Inflammation, Psoriasis, Cardiovascular Diseases	Altered Intercellular Communication	To understand the effects of psoriasis medications on systemic inflammation associated with cardiovascular risks, we studied blood proteins related to inflammation and cardiovascular disease archived from a phase 3 clinical trial of tofacitinib and etanercept in adults with moderate-to-severe psoriasis.	28927890
Liver carcinoma, Hepatitis, Chronic, Neoplasms, FAM126A gene	Altered Intercellular Communication	Purpose: Hepatocellular carcinoma (HCC) often arises in the setting of chronic liver inflammation and may be responsive to novel immunotherapies.Experimental Design: To characterize the immune microenvironment in HCC, IHC staining was performed for CD8-positive T lymphocytes, PD-1-positive, and LAG-3-positive lymphocytes, CD163-positive macrophages, and PD-L1 expression in tumor and liver background from 29 cases of resected HCC.Results: Expression of CD8 was reduced in tumor, and expression of CD163 was reduced at the tumor interface.	28928158
Inflammation, Atherosclerosis	Altered Intercellular Communication	Individual serum saturated fatty acids and markers of chronic subclinical inflammation: the Insulin Resistance Atherosclerosis Study.	28928169
Inflammation, Fever, CTCAE, Fever of Unknown Origin	Altered Intercellular Communication	The value of 18F-FDG-PET/CT in identifying the cause of fever of unknown origin (FUO) and inflammation of unknown origin (IUO): data from a prospective study.	28928271
Inflammation, Fever, CTCAE, Fever of Unknown Origin	Altered Intercellular Communication	Fever of unknown origin (FUO) and inflammation of unknown origin (IUO) are diagnostically challenging conditions.	28928271
Inflammation, Neuralgia	Altered Intercellular Communication	Animal experiment showed that LncRNA NONRATT021972 siRNA attenuated inflammation via decreasing TNF-a and alleviated neuropathic pain.	28928602
Inflammation, Mood Disorders	Altered Intercellular Communication	There has been increasing evidence that chronic low-grade inflammation is associated with mood disorders.	28929992
Inflammation, Mood Disorders	Altered Intercellular Communication	There was little evidence for inflammation markers at baseline predicting mood disorders at follow-up.	28929992
Minimal Disseminated Disease, Inflammation	Altered Intercellular Communication	The prospective unidirectional association between current MDD subtype with atypical features and hsCRP levels at follow-up suggests that inflammation may be a consequence of this condition.	28929992
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	The role of inflammation, particularly hsCRP that is critically involved in cardiovascular diseases, warrants further study.	28929992
Communicable Diseases, Inflammation, Herpesviridae Infections	Altered Intercellular Communication	Persistent herpesvirus infections including cytomegalovirus (CMV) infection may be particularly important for telomere dynamics via mechanisms such as inflammation, oxidative stress, and their impact on peripheral blood lymphocyte composition.	28931225
Malaria, Falciparum, Inflammation	Altered Intercellular Communication	Monocyte dysregulation and systemic inflammation during pediatric falciparum malaria.	28931756
Inflammation, Malaria	Altered Intercellular Communication	Inflammation and monocytes are thought to be important to human malaria pathogenesis.	28931756
Inflammation, Malaria, Acute malaria, Parasitemia	Altered Intercellular Communication	However, the relationship of inflammation and various monocyte functions to acute malaria, recovery from acute malaria, and asymptomatic parasitemia in endemic populations is poorly understood.	28931756
Inflammation	Altered Intercellular Communication	Periodontal-induced chronic inflammation triggers macrophage secretion of Ccl12 to inhibit fibroblast-mediated cardiac wound healing.	28931761
Inflammation	Altered Intercellular Communication	The goal of this study was to elucidate the molecular basis for impaired cardiac wound healing in the setting of periodontal-induced chronic inflammation.	28931761
Infarction, Inflammation	Altered Intercellular Communication	Causal network analysis of 168 inflammatory and extracellular matrix genes revealed that chronic inflammation induced by a subseptic dose of Porphyromonas gingivalis lipopolysaccharide (LPS) exacerbated infarct expression of the proinflammatory cytokine Ccl12.	28931761
Inflammation	Altered Intercellular Communication	Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation.	28931761
Inflammation, Psoriasis	Altered Intercellular Communication	Chitinase-3-Like Protein 1 (YKL-40) Is a New Biomarker of Inflammation in Psoriasis.	28932021
Inflammation	Altered Intercellular Communication	Chitinase-3-like protein 1 (YKL-40) plays a role in inflammation.	28932021
Inflammation, Psoriasis	Altered Intercellular Communication	The study was undertaken to check whether YKL-40 is a reliable biomarker of inflammation in psoriasis.	28932021
Inflammation, Psoriasis	Altered Intercellular Communication	YKL-40 could be considered as a useful biomarker of inflammation in psoriasis and is more sensitive than CRP or WBC.	28932021
Psoriatic Juvenile Idiopathic Arthritis, Inflammation	Altered Intercellular Communication	Increased YKL-40 may indicate psoriatic patients with a higher level of systemic inflammation, which may determine disease management.	28932021
Inflammation	Altered Intercellular Communication	Results showed an upregulation of key pro-inflammatory cytokine mRNA expression (TNF-a, IL-1b, IL-6) during inflammation with an associated downregulation of 11b-HSD2 mRNA expression when compared to controls.	28932959
Refractory anemias, Rheumatoid Arthritis, Inflammation, Autoimmune Disorder, CTCAE	Altered Intercellular Communication	Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic inflammation of the joints.	28933133
Arthralgia, Inflammation, Refractory anemias	Altered Intercellular Communication	We aim to investigate treatment of the nervous system to relieve joint pain and inflammation in RA.	28933133
Refractory anemias, Inflammation	Altered Intercellular Communication	Nerve mobilization, a nervous system-specific therapeutic exercise, was applied on RA patients to determine the effect of nerve mobilization on joint inflammation.	28933133
Pain Distress Question, Inflammation	Altered Intercellular Communication	Several successful cases with the use of this device are presented in which pain relief, enhancement of epithelial migration, inflammation reduction, bacterial control, and wound size reduction were achieved.	28933696
Inflammation, Venous Thrombosis	Altered Intercellular Communication	Perivascular Perfusion on Contrast-Enhanced Ultrasound (CEUS) Is Associated with Inflammation in Patients with Acute Deep Vein Thrombosis.	28933797
Inflammatory disorder, allergic inflammation, CDISC SDTM Lesion Complexity Terminology, Disease	Altered Intercellular Communication	Although allergic inflammation is characterized by a T helper (Th) 2-dominant immune response, the discovery of a role for new T cell subsets in inflammatory diseases has added an additional layer of complexity to the understanding of the pathogeneses of allergic diseases.	28934137
Inflammation	Altered Intercellular Communication	Whether intestinal damage and inflammation underlie mortality is unknown.	28934432
Inflammation	Altered Intercellular Communication	HEU infants have higher inflammation than HIV-unexposed infants until at least 6 months, which may contribute to poor health outcomes.	28934432
Paranasal Sinus Disorder, Inflammation, vinyltriethoxysilane	Altered Intercellular Communication	Overall, those with VTE had a greater disease burden and older age, sinus disease, longer hospitalization and increased inflammation were VTE risk factors.	28934665
Inflammation, Psoriasis, Dermatitis	Altered Intercellular Communication	The clinical and histologic phenotype, as well as the transcriptome, of imiquimod-induced inflammation in human skin resembles acute contact dermatitis rather than psoriasis.	28935206
Intervertebral Disc Degeneration	Altered Intercellular Communication	TGF-b1 suppresses CCL3/4 expression through the ERK signaling pathway and inhibits intervertebral disc degeneration and inflammation-related pain in a rat model.	28935976
Pain Distress Question	Altered Intercellular Communication	The results of this study indicate that TGF-b1 may represent a therapeutic target for the control of inflammation-related pain associated with IVDD.	28935976
Inflammation	Altered Intercellular Communication	Innate lymphoid cells (ILCs) have emerging roles in setting the milieu for physiological, but also pathological, immune responses and inflammation.	28936778
Inflammation	Altered Intercellular Communication	Psoriatic lesions are characterized by hyperproliferation, aberrant differentiation of keratinocytes resistant to apoptosis and inflammation.	28937251
Inflammation	Altered Intercellular Communication	Selected miRNAs, such as miR-29a-3p, miR-146a-5p or miR-222-3p with an established role in extracellular matrix formation and inflammation were associated with spinal changes and/or disease activity assessed by BASDAI in AS patients, including miR-625-3p reflecting disease activity in AS with spinal involvement.	28938006
Inflammation	Altered Intercellular Communication	We hypothesize that differential systemic levels of miRNA expression reflect miRNA dysregulation at sites of spinal inflammation or bone formation where these molecules contribute to the development of pathophysiological features typical of AxSpA.	28938006
Tumor necrosis, Inflammation	Altered Intercellular Communication	Serum adiponectin and tumor necrosis factor-a (TNF-a), a biomarker of inflammation, were also measured.	28938100
Airway structure, Bronchial Hyperreactivity	Altered Intercellular Communication	Bronchial hyperreactivity, airway inflammation, and sensitization were significantly different among the 3 groups.	28939411
Inflammatory Bowel Diseases, Communicable Diseases, Inflammation	Altered Intercellular Communication	The innate immune system of host cells provides a first-line defence against pathogenic infection, whereas an uncontrolled inflammatory response under homeostatic conditions usually leads to pathological consequences, as exemplified by the chronic inflammation of IBD.	28940253
Inflammation	Altered Intercellular Communication	Our results suggest a mixed immunological response of remodeling and inflammation following the implantation.	28940406
Delirium, Inflammation, Postoperative delirium	Altered Intercellular Communication	This report shows an incidence of 28% of delirium, occurring after CRS-HIPEC and suggests a role for systemic inflammation in the development of postoperative delirium.	28940461
Inflammation, Neoplasms	Altered Intercellular Communication	However, clinical response assessment can be problematic due to immune-related inflammation at established tumor sites.	28940544
melanoma, Neoplasms, Granulomatous inflammation	Altered Intercellular Communication	Tumor biopsies are encouraged after 4 to 6 months of TVEC administration to differentiate melanoma from granulomatous inflammation.	28940544
Inflammatory disease of mucous membrane	Altered Intercellular Communication	The investigational group also demonstrated substantial improvement in both mucosal inflammation and Valsalva maneuver at 6-week follow-up compared to controls.	28940574
Myopathy, Intestinal Pseudo-Obstruction	Altered Intercellular Communication	Among patients with a neuropathic manometry pattern and abnormal histopathology, only 23% had an enteric neuropathy, whereas 62% had neuromuscular inflammation, and 15% an enteric myopathy.	28941004
Inflammation, Fluid overload	Altered Intercellular Communication	Volume overload in these patients is associated with inflammation.	28941049
Inflammation, Carcinogenesis	Altered Intercellular Communication	Chronic inflammation may play a role in prostate cancer carcinogenesis.	28941222
Demyelination	Altered Intercellular Communication	Dynamic Changes in Brain Mesenchymal Perivascular Cells Associate with Multiple Sclerosis Disease Duration, Active Inflammation, and Demyelination.	28941240
Inflammation, Demyelination, Disease	Altered Intercellular Communication	In conclusion, we demonstrate the presence of MPC subgroups in control human brain vasculature, and their phenotypic changes in MS brain, which correlated with inflammation, demyelination and MS disease duration.	28941240
Nonalcoholic Steatohepatitis, Inflammation, Liver carcinoma, Steatohepatitis, Fibrosis Assessment, FAM126A gene, Fatty Liver Disease	Altered Intercellular Communication	Non-alcoholic steatohepatitis (NASH) is characterized by hepatic steatosis, inflammation and eventually fibrosis, and may progress to hepatocellular carcinoma (HCC).	28941732
Inflammation, Fibrosis Assessment, Fatty degeneration, Fatty Liver Disease	Altered Intercellular Communication	SNTA mRNA expression was reduced in NASH liver and negatively correlated with steatosis, inflammation, fibrosis and NASH scores.	28941732
Inflammation, Fibrosis Assessment, Diabetes Mellitus, Non-Insulin-Dependent, Fatty Liver Disease	Altered Intercellular Communication	In the NASH patients, those with type 2 diabetes had a higher fibrosis score, reduced inflammation and increased hepatic SNTA mRNA levels demonstrating a strong association of SNTA mRNA levels with inflammation.	28941732
Bronchial Epithelial Dysplasia, Inflammation, Asthma	Altered Intercellular Communication	Elderly subjects had an increase in some markers of systemic inflammation and bronchial epithelial dysfunction compared with young people with asthma.	28941741
Airway structure, Inflammation, Airway Obstruction	Altered Intercellular Communication	Asthma in the elderly presents as a specific phenotype associated with increased airway obstruction and mixed airway inflammation in addition to signs of systemic inflammation.	28941741
Inflammation	Altered Intercellular Communication	Mortality prediction in stable hemodialysis patients is refined by YKL-40, a 40-kDa glycoprotein associated with inflammation.	28941940
HD Term Type, Inflammation	Altered Intercellular Communication	Chronic inflammation contributes to increased mortality in hemodialysis (HD) patients.	28941940
Inflammation	Altered Intercellular Communication	Compared with weak PCV, severe PCV exhibited prominent immune complex deposition, complement activation, and infiltration of inflammatory cells, suggesting inflammation plays a key role in PCV progression.	28941979
Inflammation, Epidermolysis	Altered Intercellular Communication	Calcitriol Treatment Ameliorates Inflammation and Blistering in Mouse Models of Epidermolysis Bullosa Acquisita.	28942362
Granulomatous inflammation, Infectious Mononucleosis	Altered Intercellular Communication	A subsequent histological examination revealed granulomatous inflammation characteristic of infectious mononucleosis.	28942415
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	A biomarker of fibrosis, sST2, and a biomarker of inflammation, hs-CRP, predict the risk of occurrence of new-onset AF in patients with CAD.	28942872
Drug-Induced Liver Disease, Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	IL-38 may play an important role in acute and/or chronic inflammation in anticancer drug-induced lung injury and acute exacerbation of IPF.	28942884
Communicable Diseases, Inflammation	Altered Intercellular Communication	It is an evolutionary conserved multifunctional protein localized primarily in the mitochondrial matrix and has roles in inflammation and infection processes, mitochondrial ribosome biogenesis, and regulation of apoptosis and nuclear transcription.	28942965
Communicable Diseases, Inflammation	Altered Intercellular Communication	None of the patients showed signs of inflammation or infection based on clinical and laboratory examinations.	28943450
Inflammation	Altered Intercellular Communication	In addition, proteins associated with inflammation and the innate immune response-e.g., cluster of differentiation 14, annexin-2, and components of the complement system-were upregulated in PSC.	28943450
Inflammation, Cholangitis, Malignant Neoplasms	Altered Intercellular Communication	Thus, the bile-duct bile proteome of patients with PSC shows disease-specific changes associated with inflammation and the innate immune response even in the absence of obvious clinical signs of cholangitis, malignancy, or inflammation.	28943450
Chronic Obstructive Airway Disease, Pneumonitis, Diabetes Mellitus	Altered Intercellular Communication	The involvement of pulmonary inflammation in insulin resistance remains unclear, but smoking is known to be a risk factor for diabetes as well as chronic obstructive pulmonary disease.	28943558
Interstitial Fibrosis Assessment	Altered Intercellular Communication	Renal biopsy showed some sclerosed glomeruli, some with mesangial proliferation, and tubulointerstitial inflammation with eosinophils and plasma cells and mild interstitial fibrosis.	28943633
Inflammation, Asthma	Altered Intercellular Communication	T cell-associated inflammation, particularly type 2 inflammation, has an important role in asthma pathogenesis, which is suppressed by regulatory T cells (Tregs).	28944837
Symptoms, Asthma, Airway structure	Altered Intercellular Communication	Inhibition of PIM2 attenuated asthma symptoms, and improved AHR and airway inflammation compared with asthmatic mice without inhibition of PIM2.	28944837
Airway structure, Asthma, AHR wt Allele, Symptoms	Altered Intercellular Communication	In conclusion, PIM2 may exhibit an important role in asthma pathogenesis and exacerbate AHR, airway inflammation and asthma symptoms.	28944837
Inflammation	Altered Intercellular Communication	It plays critical roles in various tissues throughout development and is implicated in tumorigenesis and inflammation in adulthood.	28945198
Acromegaly, Sialorrhea	Altered Intercellular Communication	Acromegaly is characterized by growth hormone (GH) and insulinlike growth factor-1 (IGF-1) hypersecretion, and GH and IGF-1 play important roles in regulating body composition and glucose homeostasis.	28945897
Gastritis	Altered Intercellular Communication	There was a significant (p = 0.027) relationship between the IL-1b 511 C-carrier and histological gastric inflammation in H. pylori-infected gastritis patients.	28946145
Inflammation, Insulin Resistance	Altered Intercellular Communication	Both insulin-resistance and chronic low-grade inflammation are involved in this relationship.	28946871
Inflammation, Destruction of tissue	Altered Intercellular Communication	Usually, the foreign objects cause chronic inflammation and local tissue destruction, which give rise to symptoms.	28946895
Inflammation	Altered Intercellular Communication	Alveolar bone graft surgery was delayed because of local chronic inflammation due to the foreign object.	28946895
Inflammation	Altered Intercellular Communication	It can be concluded that a new factor -namely the dialysis technique- may be associated with falling testosterone levels and the associated loss of muscle mass and inflammation.	28946965
Inflammation, Rheumatoid Arthritis, Disease remission	Altered Intercellular Communication	Traditional markers of inflammation are often required for inclusion in rheumatoid arthritis trials, yet patients with active disease may have normal lab tests.	28947312
Inflammation	Altered Intercellular Communication	CE findings were normal in 17 patients (40%), mild inflammation in 19 (44%), and moderate to severe inflammation in 7 (16%).	28947363
Clinical Events Domain, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Of the 26 patients (60%) with mucosal inflammation on CE, 85% had elevated baseline fecal calprotectin and 77% elevated lactoferrin level.	28947363
Inflammation	Altered Intercellular Communication	Calprotectin and lactoferrin were normal in all patients without inflammation and elevated in all with moderate to severe inflammation.	28947363
Clinical Events Domain, Inflammatory disease of mucous membrane	Altered Intercellular Communication	During follow-up, 14% of patients exhibited a clinical flare; all had mucosal inflammation at CE and 83% had elevated baseline calprotectin and lactoferrin levels.	28947363
Motor Neuron Disease, Inflammation, Dysbiosis	Altered Intercellular Communication	Gut inflammation and dysbiosis in human motor neuron disease.	28947596
Gastrointestinal inflammation	Altered Intercellular Communication	A majority of patients had signs of intestinal inflammation.	28947596
ARCN1 gene, Inflammation	Altered Intercellular Communication	Serum levels of Gal-3 in 44 patients with COPD were further analyzed and correlated with the parameters of lung function and the biomarkers of systemic inflammation.	28947730
ARCN1 gene, Inflammation	Altered Intercellular Communication	CONCLUSIONS Our results indicated that serum Gal-3 is increased in AECOPD patients, which is also positively associated with systemic inflammation and smoking in patients with COPD, suggesting that Gal-3 might be a valuable biomarker for AECOPD.	28947730
Inflammation	Altered Intercellular Communication	Cancer-related inflammation appears to have a greater impact on taste perception than an acute inflammatory process.	28948404
Crohns disease of large bowel", Ulcerative Colitis, Colitis	Altered Intercellular Communication	For the noninvasive monitoring of the activity of colonic inflammation, we validated a symptom index suitable for ulcerative colitis and colonic Crohn's disease.	28948412
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	We also evaluated the correlation of the patient-reported influence of the IBD in the daily life, measured by a VAS, with the inflammation activity.	28948412
Inflammation	Altered Intercellular Communication	The results of the symptom index demonstrated a statistically significant correlation with the rapid calprotectin test, histological inflammation activity, and the VAS.	28948412
Inflammation	Altered Intercellular Communication	No correlations were found between the VAS and calprotectin or the histological inflammation activity.	28948412
Inflammation	Altered Intercellular Communication	The sensitivity of the combination index to detect active inflammation was slightly superior to fecal calprotectin alone.	28948412
Inflammation	Altered Intercellular Communication	The new symptom index and the combination index are simple, noninvasive means for distinguishing remission from active inflammation in colonic IBD.	28948412
Inflammation	Altered Intercellular Communication	In 64.8% of the procedures, the mucosa was inflamed; however, 14.7% did not show histological inflammation.	28949435
Inflammation	Altered Intercellular Communication	Endoscopic remission was observed in the other 35.2% of procedures; however, in biopsies 21.6% exhibited histological inflammation.	28949435
Inflammation, Wheezing, MS4A2 wt Allele, Comorbidity	Altered Intercellular Communication	We included very young consecutive children presenting with recurrent wheezing who had been evaluated for the severity of wheezing, associated atopic comorbidities, and tested for biomarkers of atopy and inflammation.	28950434
Inflammation, Viral respiratory infection	Altered Intercellular Communication	Association between the TT-genotype of IL-4 rs2070874 polymorphism and a severe phenotype of viral-induced wheeze further underlines the role IL-4 plays in the inflammation pathway leading to viral respiratory infections.	28950434
Hormone abnormality, Polycystic Ovary Syndrome	Altered Intercellular Communication	The drug is also associated with hormonal disorders, polycystic ovary and reduced fertility.	28950817
Inflammation, Psoriasis, Cardiovascular system	Altered Intercellular Communication	Psoriasis patients experience chronic systemic skin inflammation and develop cardiovascular comorbidities that shorten their lifespan.	28951241
Dermatitis, Neutrophilia (finding), Monocytosis, Luminal Carotid Thrombus	Altered Intercellular Communication	KC-Tie2 mice develop psoriasiform skin inflammation with increases in IL-23 and IL-17A and proinflammatory monocytosis and neutrophilia that precedes development of carotid artery thrombus formation.	28951241
Inflammation, Thrombosis	Altered Intercellular Communication	Skin inflammation; thrombosis clotting times; and percentage of splenic monocytes, neutrophils, and CD4 T cells were examined.	28951241
Inflammation, Psoriasis	Altered Intercellular Communication	Skin inflammation significantly improved in KC-Tie2 mice treated with each of the antibodies targeting IL-23, IL-17A, or IL-17RA, consistent with clinical efficacy observed in psoriasis patients.	28951241
Inflammation, Neutropenia	Altered Intercellular Communication	This decrease in skin inflammation paralleled decreases in splenic neutrophils (CD11b+Ly6G+) but not monocytes (CD11b+Ly6Chigh) or T cells (CD4+).	28951241
Inflammation	Altered Intercellular Communication	Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health.	28951559
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	increased inflammation as assessed by C-reactive protein, low serum high-density lipoprotein cholesterol and high triglycerides, which are all known to indicate increased risk of cardiovascular disease.	28951559
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Characterization of neutrophil-to-lymphocyte ratio as a measure of inflammation in rheumatoid arthritis.	28952205
Inflammation	Altered Intercellular Communication	The neutrophil to lymphocyte ratio (NLR) is one of the well-recognized sensitive measures of inflammation.	28952205
Refractory anemias, Inflammation	Altered Intercellular Communication	In contrast to the traditional markers, NLR may serve as a less expensive and effective measure of inflammation in RA.	28952205
Inflammation, Thrombosis, Primary malignant neoplasm	Altered Intercellular Communication	The role of Protein Z (PZ) in conditions, such as thrombosis, inflammation or cancer, is under investigation.	28952223
Virus Diseases, Chronic inflammation, Malignant Neoplasms	Altered Intercellular Communication	This holistic approach to care includes detection of malignancies that are associated with certain viral infections, with chronic inflammation, and with lifestyle choices.	28952428
Early Hepatocellular Carcinoma	Altered Intercellular Communication	Inflammation-nutrition scope predicts prognosis of early-stage hepatocellular carcinoma after curative resection.	28953624
Inflammation, Panophthalmitis, Squamous cell carcinoma, Tuberculosis, Pulmonary, Endophthalmitis, CTCAE	Altered Intercellular Communication	Other frequent indications included endophthalmitis (6.3%), nonspecific inflammation (4.1%), squamous cell carcinoma (3.6%), panophthalmitis (3.4%), and phthisis bulbi (1.2%).	28954020
Granulomatous inflammation, Ulcer	Altered Intercellular Communication	Asynovial fluid culture yielded Mycobacterium tuberculosis, and a forearm ulcer biopsy showed granulomatous inflammation.	28954084
Inflammation, Bone necrosis	Altered Intercellular Communication	Histologically, persistent inflammation and extensive osteonecrosis were seen in group 4.	28954199
Inflammation	Altered Intercellular Communication	There was no other clinical involvement, biological inflammation, or autoantibodies.	28954874
Inflammation, Cholecystitis	Altered Intercellular Communication	This study indicated that the severe inflammation indicated by high CRP values during cholecystitis attacks predicts the need for an additional port.	28954990
Virus Diseases	Altered Intercellular Communication	While the pathogenesis of the disease is unknown, it is traditionally hypothesized that the viral infection occurs by neuronal transmission directly from peripheral sites.	28956417
Inflammation, Burn, CTCAE	Altered Intercellular Communication	We report a severe ocular burn case that illustrates in-office management to promote rapid re-epithelialization and reduce inflammation to restore ocular surface integrity.	28957834
Conjunctivitis	Altered Intercellular Communication	Examination revealed diffuse conjunctival inflammation and extensive corneal, conjunctival, and limbal epithelial defects in the left eye; hence, application of cryopreserved AM was performed.	28957834
Inflammation	Altered Intercellular Communication	Placement of three self-retained AMs over a 10-day period resulted in resolution of symptoms, reduction in inflammation, complete re-epithelialization of corneal and limbal defects, and improvement of visual acuity from 20/50 to 20/20.	28957834
Conjunctivitis	Altered Intercellular Communication	Intriguingly, areas of conjunctival inflammation not covered by the AM remained inflamed.	28957834
Inflammation	Altered Intercellular Communication	In this case of acute chemical burn, application of self-retained AM 24 hours after injury was effective in promoting ocular surface healing, reducing inflammation, and restoring visual acuity.	28957834
Inflammation, Acute pulmonary embolism	Altered Intercellular Communication	Comparison of acute and convalescent biomarkers of inflammation in patients with acute pulmonary embolism treated with systemic fibrinolysis vs. placebo.	28957940
Inflammation, Pulmonary Embolism, Venous Thromboembolism, vinyltriethoxysilane	Altered Intercellular Communication	: Previous studies have associated biomarkers indicative of acute inflammation with pulmonary embolism, which may amplify coagulation, inhibit fibrinolysis and increase risk of venous thromboembolism (VTE) recurrence.	28957940
Inflammation, Acute pulmonary embolism	Altered Intercellular Communication	Acute pulmonary embolism causes marked but transient inflammation, as demonstrated by the significant elevation in the inflammatory biomarkers at diagnosis, followed by their reduction in more than 80% of patients at 3-month follow-up.	28957940
Inflammation, Metabolic Syndrome X, Diabetes Mellitus	Altered Intercellular Communication	Clusterin (Clu), also known as apolipoprotein J (ApoJ), is a highly conserved disulfide-linked heterodimeric glycoprotein implicated in a great variety of physiological and pathophysiological processes including lipid transportation, tissue remodeling, senescence, cell interaction, stress response, inflammation, apoptosis, diabetes mellitus and metabolic syndrome.	28958138
Inflammation, Chronic heart failure	Altered Intercellular Communication	Utility of Growth Differentiation Factor-15, A Marker of Oxidative Stress and Inflammation, in Chronic Heart Failure: Insights From the HF-ACTION Study.	28958347
Arterial Stiffness, Inflammation, Glycation End Products, Advanced, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	High intake of dietary advanced glycation end-products is associated with increased arterial stiffness and inflammation in subjects with type 2 diabetes.	28958695
Diastolic dysfunction, Hypernatremia, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Osteoglycin prevents the development of age-related diastolic dysfunction during pressure overload by reducing cardiac fibrosis and inflammation.	28958774
Cardiac Hypertrophy, Fibrosis Assessment, Inflammation, Hypertensive heart disease	Altered Intercellular Communication	However, whether osteoglycin modulates cardiac hypertrophy, fibrosis or inflammation in hypertensive heart disease and during aging remains unknown.	28958774
Hypernatremia, Inflammation	Altered Intercellular Communication	Angiotensin-II-induced pressure overload increases cardiac osteoglycin expression, concomitant with the onset of inflammation and extracellular matrix deposition.	28958774
Diastolic dysfunction, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	However, Angiotensin-II infusion in combination with aging resulted in exaggerated cardiac fibrosis and inflammation in the osteoglycin null mice as compared to wild-type mice, resulting in increased diastolic dysfunction as determined by magnetic resonance imaging.	28958774
Hypernatremia, Inflammation, Fibrosis Assessment, Diastolic dysfunction	Altered Intercellular Communication	In conclusion, osteoglycin expression is increased in the heart in response to pressure overload and its absence results in increased cardiac inflammation and fibrosis resulting in increased diastolic dysfunction.	28958774
palladium	Altered Intercellular Communication	Increasing evidence has suggested that the GABAergic neurotransmitter system is involved in the pathogenesis of PD.	28960581
Inflammation, Cachexia, Anorexia	Altered Intercellular Communication	Inflammation, use of loop diuretics, and cachexia are associated with an increased likelihood of anorexia in patients with HF, and patients with anorexia showed impaired functional capacity and poor outcomes.	28960880
Dermatitis	Altered Intercellular Communication	Long-term exposure to ultraviolet (UV) irradiation causes skin inflammation and aging.	28961200
Inflammation	Altered Intercellular Communication	Angiopoietin-like protein 2 (Angptl2) is a mediator of chronic inflammation that contributes to extracellular matrix remodeling.	28962551
Inflammation, selenium	Altered Intercellular Communication	Data on ACPA, smoking, SE, inflammation (C-reactive protein) and disease activity score in 28 joints (DAS28) was obtained from the EIRA database.	28962582
Inflammation	Altered Intercellular Communication	AAV severity was associated with markers reflecting organ involvement (TKT, CD93, and TNC) rather than inflammation.	28962592
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Soluble levels and endogenous vascular gene expression of KLOTHO are related to inflammation in human atherosclerotic disease.	28963437
Inflammation, Atherosclerosis	Altered Intercellular Communication	Our study indicates an inverse interrelationship between inflammation and Klotho in atherosclerosis.	28963437
Inflammation, COL4A2 wt Allele	Altered Intercellular Communication	These findings, which should be validated through a larger study, suggest that inflammation plays an important role in mediating outcomes after ICH.	28964648
Kidney Failure, Chronic, Inflammation, Malnutrition, Atherosclerosis, Cardiovascular morbidity, Endothelial dysfunction	Altered Intercellular Communication	Inflammation and malnutrition play an important role in endothelial dysfunction, atherosclerosis and excessive cardiovascular morbidity and mortality in ESRD patients AIM OF THE STUDY: The primary objective is to determine the prevalence of inflammation, malnutrition and atherosclerosis in patients on maintenance haemodialysis.	28964721
Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	Secondary objective was to determine the association for atherosclerosis with inflammation and malnutrition.	28964721
Inflammation, Malnutrition, Atherosclerosis	Altered Intercellular Communication	Atherosclerosis was present in 65.3%: 58.4% of patients had malnutrition and 43.6% had inflammation.	28964721
Inflammation, Malnutrition, Carotid Atherosclerosis	Altered Intercellular Communication	Inflammation (high serum CRP) and malnutrition (low serum albumin) in patients on haemodialysis are significantly associated with carotid atherosclerosis.	28964721
Inflammation	Altered Intercellular Communication	A panel of serum and urine biomarkers of inflammation and joint degradation were evaluated.	28964890
Degenerative polyarthritis	Altered Intercellular Communication	Consequently, ABT-981 may provide clinical benefit to patients with inflammation-driven OA.	28964890
Pancreatic carcinoma	Altered Intercellular Communication	Here, we reported that increased neurotransmitter adrenaline was associated with the poor survival in pancreatic cancer patients.	28965949
Inflammation	Altered Intercellular Communication	The prevalence of follicles, papillary inflammation and scarring were 33.6, 31.6, and 28.5%, respectively.	28966918
Communicable Diseases, Inflammation	Altered Intercellular Communication	In individuals with inflammation in the absence of infection the IFNG/IL22 and NK cell response was reduced, however, pro-inflammatory, growth and matrix factors remained upregulated and mucins were downregulated.	28966918
Inflammation	Altered Intercellular Communication	Interestingly, females appear more susceptible to developing papillary inflammation and scarring than males, even at this young age, despite comparable levels of C. trachomatis infection.	28966918
Respiratory distress, Pneumonitis	Altered Intercellular Communication	The club cell protein (CC-16) is a biomarker associated with respiratory distress and pulmonary inflammation.	28967121
Colorectal Carcinoma	Altered Intercellular Communication	How systemic inflammation-based prognostic scores such as the modified Glasgow Prognostic Score (mGPS) and neutrophil:lymphocyte ratio (NLR) differ across populations of patients with colorectal cancer (CRC) remains unknown.	28967380
Inflammation, Heart failure	Altered Intercellular Communication	Proteomic profiling identified several novel associations between proteins involved in apoptosis, inflammation, matrix remodelling, and fibrinolysis with incident heart failure in elderly individuals.	28967680
Inflammation	Altered Intercellular Communication	About 900 DMRs were found and their associated genes were significantly enriched in 32 pathways, the top ones of which were associated with insulin resistance and inflammation.	28967791
Inflammation, Rosacea, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation and oxidative stress are involved in the etiopathogenesis of rosacea and chronic kidney disease (CKD).	28968402
Ocular Hypertension, Inflammation, Uveitis	Altered Intercellular Communication	Ocular hypertension (OHT) caused by inflammation or corticosteroid treatment is a common complication of uveitis.	28968412
Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	K-115 decreased IOP in both inflammation- and corticosteroid-induced OHT associated with uveitis and played a synergistic role in reducing ocular inflammation in uveitis treatment.	28968412
vascular inflammations, Cerebrovascular accident	Altered Intercellular Communication	Myeloperoxidase plays a central role in initiation and progression of vascular inflammation, but prior studies linking myeloperoxidase with stroke risk have been inconclusive.	28969386
Cerebrovascular Disorders, Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Furthermore, these results support a rationale for chronic inflammation as a potential modifiable stroke risk mechanism, and suggest that immune-targeted therapies could be useful for treatment and prevention of cerebrovascular disease.	28969386
Endothelium, Atherosclerosis	Altered Intercellular Communication	Current paradigms suggest atherosclerosis is a chronic, dynamic, inflammatory condition precipitated in response to endothelial injury from various environmental challenges.	28969386
vascular inflammations, Arterial Injury	Altered Intercellular Communication	Furthermore, liraglutide treatment suppressed hyperglycemia-enhanced vascular inflammation 7 days after arterial injury.	28969637
Inflammation, Rheumatoid Arthritis, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	Chronic kidney disease, inflammation, and cardiovascular disease risk in rheumatoid arthritis.	28969969
Refractory anemias, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Recently, chronic kidney disease (CKD) was suggested to increase the risk of CVD in RA patients, and inflammation was identified as a critical, nontraditional CKD-associated risk factor for CVD.	28969969
Refractory anemias, Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	The coexistence of CKD and inflammation was associated with a higher risk of CVD than either condition alone in RA patients.	28969969
Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Kidney Diseases	Altered Intercellular Communication	Inflammation might increase the risk of CVD especially in patients with CKD.	28969969
Refractory anemias, Rheumatoid Arthritis, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	Rheumatoid arthritis (RA), a prototypic systemic autoimmune inflammatory condition, confers an increased risk of cardiovascular disease (CVD).	28969969
Inflammation, Fibrosis Assessment, Granuloma, Foreign-Body	Altered Intercellular Communication	The degree of chronic inflammation, fibrosis, foreign-body giant cell reactions, the number of capillary vessels and nerve fibers, and the presence or absence of adipose tissue were recorded.	28970142
Inflammation, Fibrosis Assessment, Giant Cells, Foreign-Body	Altered Intercellular Communication	In most cases, mild to moderate chronic inflammation with a mild degree of foreign-body giant cell reaction and minimal to mild fibrosis were found in explanted mesh specimens.	28970142
Inflammation, Pain Distress Question	Altered Intercellular Communication	Mast Cell-Intervertebral disc cell interactions regulate inflammation, catabolism and angiogenesis in Discogenic Back Pain.	28970490
Inflammation	Altered Intercellular Communication	Both FBX011 and TGIF1 are involved in TGF-b signalling, suggesting this pathway may be important in the transition from acute to chronic middle ear inflammation, and a potential molecular target.	28970529
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	In patients with chronic kidney disease (CKD), microinflammation with an increased percentage of CD14+ /CD16++ inflammatory monocytes has been reported, even with no clinical evidence of inflammation.	28971592
Sporothrix, Autoimmune reaction, Inflammatory abnormality of the eye	Altered Intercellular Communication	Sporothrix infection should be included in the differential diagnosis for ocular inflammation, regardless of the presence or absence of autoimmune comorbidities and whether the patient resides in an endemic area or not.	28972025
Inflammation, Erythema	Altered Intercellular Communication	Finally, selected formulations were also analyzed in an erythema model for testing formulations on UV-induced inflammation.	28972949
Inflammation, Prediabetes syndrome, Cardiovascular Diseases	Altered Intercellular Communication	We investigated diastolic function and its association with markers of glycation and inflammation related to cardiovascular disease in patients with prediabetes.	28973588
Inflammation, Plaque, Atherosclerotic	Altered Intercellular Communication	Altogether, these results show that adequate endothelial autophagic flux under high SS limits atherosclerotic plaque formation by preventing endothelial apoptosis, senescence, and inflammation.	28973855
Inflammation, Hematoma, Thrombosis, Hemorrhage, Pseudoaneurysm	Altered Intercellular Communication	In-hospital observation showed vascular perforation/bleeding in 4.7%, proximal hematoma in 9.3%, distal hematoma in 4.7%, pseudoaneurysm in 1.2%, thrombosis in 1.2%, puncture-site bleeding in 3.5%, and local inflammation in 1.2%.	28974660
Inflammation, Obesity	Altered Intercellular Communication	Data herein show that distinct protein profiles identify specific peptides belonging to lipid metabolism and inflammation processes that are associated with obesity and vitamin D deficiency.	28974732
Hereditary Diseases, Inflammation, Brucellosis	Altered Intercellular Communication	Familial Mediterranean fever is a hereditary disease, characterized by recurrent episodes of inflammation.	28975396
Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Liver Cirrhosis	Altered Intercellular Communication	Regression analysis revealed that G allele odds of having cirrhosis was 3.9 times compared to C. The G allele was also significantly associated with steatosis, lobular inflammation, NAFLD activity score, and fibrosis.	28975533
Inflammation	Altered Intercellular Communication	Both implant and teeth developed similar increased response of inflammation at 14 days compared to day 0: BoPs of 4.2+-1.8 (P=0.06) and BoPs of 3.1+-2.2 (P=0.048) for implant and tooth, respectively.	28975772
Refractory anemias, Inflammation, MIR20A gene	Altered Intercellular Communication	MiR-20a plays a role in mediating synovial inflammation in RA.	28975975
Inflammation	Altered Intercellular Communication	Patients with cHepC had increased inflammation compared to the healthy controls.	28976873
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	End-stage renal disease (ESRD) patients had higher levels of inflammation markers (NLR, IgG, CRP and YKL-40) and lower HCV RNA levels, HAI and FS compared to non-uremic patients.	28976873
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Cytoplasmic chromatin triggers inflammation in senescence and cancer.	28976970
Inflammation, Primary malignant neoplasm, Destruction of tissue	Altered Intercellular Communication	Here we show that cytoplasmic chromatin activates the innate immunity cytosolic DNA-sensing cGAS-STING (cyclic GMP-AMP synthase linked to stimulator of interferon genes) pathway, leading both to short-term inflammation to restrain activated oncogenes and to chronic inflammation that associates with tissue destruction and cancer.	28976970
Inflammation, Ionizing radiation	Altered Intercellular Communication	Mice deficient in STING show impaired immuno-surveillance of oncogenic RAS and reduced tissue inflammation upon ionizing radiation.	28976970
Inflammatory disorder	Altered Intercellular Communication	Targeting the cytoplasmic chromatin-mediated pathway may hold promise in treating inflammation-related disorders.	28976970
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Although the precise mechanisms are still unclear, irisin, RBP-4, adiponectin and PTX-3 are hallmarks of the MetS, which is related to low-grade inflammation.	28977161
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Ultrasound of the hand is sufficient to detect subclinical inflammation in rheumatoid arthritis remission: a post hoc longitudinal study.	28978340
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Ultrasound (US) is a sensitive method for detecting joint/tendon inflammation in patients with rheumatoid arthritis (RA).	28978340
Refractory anemias, Inflammation	Altered Intercellular Communication	Subclinical inflammation is often found in patients with RA in composite score remission.	28978340
Refractory anemias, Inflammation	Altered Intercellular Communication	The purpose of the present study was to explore whether US of only the hands is sufficient to identify subclinical inflammation in patients with established RA in clinical remission.	28978340
Refractory anemias, Inflammation	Altered Intercellular Communication	US examination performed only of the hands captured >= 90% of patients with subclinical inflammation and could be feasible for assessing bDMARD-treated patients with RA in remission.	28978340
Inflammation, Small bowel obstruction	Altered Intercellular Communication	A large enterolith was found to be impacted in the jejunum just distal to the area of inflammation resulting in small bowel obstruction.	28978602
Urolithiasis, Pyelonephritis, Nephritis, Hydronephrosis	Altered Intercellular Communication	BACKGROUND Xanthogranulomatous pyelonephritis (XP) is an extremely rare, severe, atypical form of chronic renal parenchymal inflammation accompanied by hydronephrosis and/or urolithiasis.	28978905
Necrotizing granulomatous inflammation	Altered Intercellular Communication	Significant CD68-positive cell infiltrations and scattered foam cells arranging the numerous foci of granuloma inflammation were noticed.	28978905
ARCN1 gene, Inflammation	Altered Intercellular Communication	Differences in systemic inflammation between cigarette and biomass smoke-induced COPD.	28979110
ARCN1 gene, Inflammation	Altered Intercellular Communication	It is known that biomarkers of systemic inflammation are raised in COPD caused by tobacco (T-COPD) compared with healthy controls, but there is less information on the inflammatory status of subjects with COPD caused by biomass smoke (B-COPD).	28979110
ARCN1 gene, Inflammation	Altered Intercellular Communication	Both types of COPD are associated with high levels of systemic inflammation biomarkers.	28979110
Airway structure	Altered Intercellular Communication	Cell count in induced sputum is a noninvasive biomarker to assess airway inflammation phenotypes.	28979112
Inflammation, Fibrosis Assessment, Retractile Mesenteritis	Altered Intercellular Communication	A biopsy was performed, revealing benign chronic inflammation, fibrosis and IgG4-positive plasmocytes consistent with sclerosing mesenteritis.	28979630
Inflammatory disorder	Altered Intercellular Communication	Complement factor 5a (C5a) may be involved in many inflammation disorders.	28981167
Inflammation, Carcinoma of lung	Altered Intercellular Communication	A prospective study of immune and inflammation markers and risk of lung cancer among female never smokers in Shanghai.	28981818
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Here, we have carried out the first large study of circulating inflammation markers and lung cancer risk among female never smokers in Shanghai.	28981818
Inflammation, Carcinoma of lung	Altered Intercellular Communication	Markers involved in various aspects of the immune response were associated with subsequent lung cancer risk, implicating inflammation in the etiology of lung cancer among female never smokers.	28981818
Inflammation, No metabolic abnormalities, Pancreatitis	Altered Intercellular Communication	Emerging evidence shows that chronic low-grade inflammation and changes in markers of innate immunity are implicated in a range of metabolic abnormalities following an episode of acute pancreatitis.	28982582
Inflammation, Primary malignant neoplasm, Communicable Diseases, Anal carcinoma, Postoperative Complications, Inflammatory disorder	Altered Intercellular Communication	Abdominoperineal resection (APR) has been performed for lower rectal cancer, anal cancer and inflammatory diseases, but is associated with postoperative complications such as inflammation of pelvic dead space or perineal wound infection.	28982899
Inflammation, Infection	Altered Intercellular Communication	None developed postoperative dead space inflammation or perineal wound infections.	28982899
Inflammation	Altered Intercellular Communication	A picture of periportal inflammation was still detected in 4 cases, with no evidence of inflammatory lesions in the remaining cases.	28983074
Inflammation, Carcinogenesis	Altered Intercellular Communication	Adipokines, and other inflammation molecules linked to adiposity, are suspected to be involved in breast carcinogenesis, however prospective findings are inconclusive.	28983080
Inflammation, Breast Carcinoma	Altered Intercellular Communication	These findings constitute further evidence that inflammation plays a role in breast cancer.	28983080
Inflammation	Altered Intercellular Communication	Identified DASGs were associated with myogenesis, adipogenesis, protein ubiquitination, and inflammation.	28984045
Blood Clot	Altered Intercellular Communication	Fifty-eight cases (41%) had findings warranting further analysis, including alterations in glomerular matrix and/or cellularity, atypical or pigmented casts, thrombi, tubulointerstitial or vascular inflammation, or deposition of amorphous material.	28984299
Inflammation, Lymphoma	Altered Intercellular Communication	Purpose To analyze the frequency and distribution of low-signal-intensity regions (LSIRs) in lymphoma lesions and to compare these to fluorodeoxyglucose (FDG) uptake and biologic markers of inflammation.	28985135
methyldopa, Inflammation	Altered Intercellular Communication	Inflammation is a key pathogenic factor in age-related macular degeneration (AMD).	28985220
Inflammation, Pathology, Nerve Degeneration	Altered Intercellular Communication	Although each disease has particular pathologies and symptoms, accumulated evidence points to similar mechanisms of neurodegeneration, including inflammation, oxidative stress, and protein aggregation.	28985333
Inflammation	Altered Intercellular Communication	CD4+CXCR5+ T cells from CAD patients also demonstrated more potent capacity to stimulate B cell inflammation than those from healthy individuals.	28985621
Atherosclerosis	Altered Intercellular Communication	The major contributing event is atherosclerosis, which is a progressive inflammatory condition resulting in the thickening of the arterial wall and the formation of atheromatous plaques.	28985621
Inflammation, De Quervain Disease, Tenosynovitis	Altered Intercellular Communication	De Quervain's tenosynovitis is a repetitive strain injury involving synovial inflammation of the tendons of the first extensor compartment of the wrist.	28985641
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	The exact role of this parasite in acute appendicitis is controversial as usually resected specimens show no evidence of histological inflammation.	28985767
Inflammation, Neoplasms, Communicable Diseases, Traumatic injury, Glaucoma, CTCAE	Altered Intercellular Communication	The leading pathologic causes of eye removal were neoplasm (36%), glaucoma (21%), infection or inflammation (17%), and trauma (16%).	28985809
Inflammation, Pathology, Neoplasms, Traumatic injury, Glaucoma, CTCAE	Altered Intercellular Communication	Common pathologies included glaucoma, neoplasms, infection/inflammation, and trauma.	28985809
Acute myocardial infarction, vascular inflammations, Thrombosis	Altered Intercellular Communication	The alarmin family member myeloid-related protein (MRP)-14 (S100A9), which has been identified by platelet transcriptional profiling as an acute myocardial infarction gene, regulates vascular inflammation and thrombosis.	28986057
Inflammation, Thrombosis, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	MRP-8/14 is positioned as a unique biomarker at the interface of inflammation and thrombosis in ACS.	28986057
Inflammation, atherosclerotic	Altered Intercellular Communication	We found altered relationships between PC and lysoPC profiles, inflammation, and arterial function in atherosclerotic patients, compared to healthy subjects.	28986077
Airway structure, ARCN1 gene, Bronchoconstriction	Altered Intercellular Communication	Medicines targeting bronchoconstriction and airway inflammation are the current mainstays of COPD therapy.	28986203
Inflammation, Lung Injury, mucus secretion	Altered Intercellular Communication	Previous studies have indicated that inhalation of unfractionated heparin (UFH) treats local inflammation, mucus hypersecretion and lung injury, without systemic anticoagulation, and is safe.	28986203
Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Idiopathic pulmonary fibrosis (IPF) is characterized by a disturbed pulmonary redox balance associated with inflammation.	28987380
Inflammation, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Collectively, our findings implicate that IPF patients may benefit from the use of quercetin to restore the disturbed redox balance and reduce inflammation.	28987380
Inflammation, Fatty degeneration, Alcoholic Liver Diseases, Liver Cirrhosis	Altered Intercellular Communication	Chronic, excessive alcohol consumption leads to alcoholic liver disease (ALD) characterized by steatosis, inflammation, and eventually cirrhosis.	28987423
Inflammation, Fatty degeneration	Altered Intercellular Communication	Mice given injections of the anti-MIR122 before ethanol feeding had increased steatosis, inflammation, and serum levels of alanine aminotransferase compared with mice given a control vector.	28987423
carotid disease	Altered Intercellular Communication	Circulating inflammation-resolving lipid mediators RvD1 and DHA are decreased in patients with acutely symptomatic carotid disease.	28987721
Resolvin	Altered Intercellular Communication	Resolvins are endogenous inflammation-resolving lipid mediators that are induced by inflammatory insults.	28987721
Inflammation	Altered Intercellular Communication	We hypothesized that increased inflammatory activation, manifested as increased GlycA, a novel biomarker of global inflammation, would be evident in Palestinians.	28987777
Inflammation, Cardiovascular Diseases, Diabetes Mellitus	Altered Intercellular Communication	This propensity to inflammation may be a driver of the higher risk of cardiovascular disease, insulin resistance and diabetes observed in this population.	28987777
Inflammation, Arthropathy	Altered Intercellular Communication	The underlying mechanism of joint dysfunction involves increased oxidative stress, inflammation, high levels of cartilage extracellular matrix degrading proteases and decline in autophagy-a mechanism of cellular defense.	28987943
Trachoma , Perifolliculitis	Altered Intercellular Communication	When analyzed by the presence or absence of individual WHO simplified system signs of active trachoma, trachomatous inflammation-follicular cases constituted18% (95% CI: 15.9-20.2%), while 4.7% (95% CI: 3.6-5.8%) were trachomatous inflammation-intense cases.	28988540
Inflammation, Metabolic Diseases, Cardiovascular Diseases, Diabetes Mellitus, Virus Diseases	Altered Intercellular Communication	These "healthy" components of our diet are often referred to as nutraceuticals and they can prevent/suppress: aging, bacterial, fungal and viral infections, diabetes, inflammation, metabolic disorders and cardiovascular diseases and have other health-enhancing effects.	28988970
Eosinophilic esophagitis, Esophagitis	Altered Intercellular Communication	Comparison of endoscopy and radiographic imaging for detection of esophageal inflammation and remodeling in adults with eosinophilic esophagitis.	28989006
Esophagitis, "Extra-osseous Ewings sarcoma	Altered Intercellular Communication	Eosinophil predominant mucosal inflammation is central to the diagnosis and activity assessment of eosinophilic esophagitis (EoE).	28989006
Esophagitis	Altered Intercellular Communication	The aim of this study was to compare upper endoscopy (EGD) with barium upper GI study (UGI) for the detection of esophageal inflammation and remodeling in adults with EoE.	28989006
Inflammation, Cerebrovascular accident, Atherosclerosis	Altered Intercellular Communication	Stroke caused by atherosclerosis remains a leading cause of morbidity and mortality worldwide, associated with carotid plaque rupture and inflammation progression.	28990089
Inflammation	Altered Intercellular Communication	The hormonal background may be involved in inappropriate inflammation and increased stenosis susceptibility.	28990664
Inflammation	Altered Intercellular Communication	The hormonal background may be involved in inappropriate inflammation and increased stenosis susceptibility.	28990664
Necrosis with inflammation	Altered Intercellular Communication	The serum concentrations of protective marker adiponectin and bone necrosis inflammation factor IL-33 concentrations were also examined.	28990818
Granulomatous inflammation	Altered Intercellular Communication	Histopathological evaluation of pericardial tissue revealed granulomatous inflammation.	28990950
Inflammation, Ulceration, CTCAE, Granuloma	Altered Intercellular Communication	There were no differences in those 7 patients and the remaining 28 in terms of diagnosis at colectomy, primary pouch symptoms, prepouch inflammation, ulceration, or granulomas at endoscopy.	28991085
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	The VAO, glaucoma, and inflammation were comparable 12 months postoperatively.	28991614
Inflammation, Infection, Ischemic stroke	Altered Intercellular Communication	Previous infections could increase the risk of ischemic stroke by an activation of systemic inflammation.	28991723
Inflammation, Fibrosis Assessment, Pancreatic carcinoma	Altered Intercellular Communication	Fatty Acid-Mediated Stromal Reprogramming of Pancreatic Stellate Cells Induces Inflammation and Fibrosis That Fuels Pancreatic Cancer.	28991878
Inflammation, Fibrosis Assessment, Carcinogenesis, Pancreatic carcinoma	Altered Intercellular Communication	Inflammation and fibrosis levels were increased in pancreatic cancer specimens, supporting the in vitro observations and suggesting that PSCs contribute to pancreatic carcinogenesis.	28991878
Rheumatoid Arthritis	Altered Intercellular Communication	Arterial Inflammation Detected With 18 F-Fluorodeoxyglucose-Positron Emission Tomography in Rheumatoid Arthritis.	28992382
Inflammation, Cardiovascular Diseases, Refractory anemias, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Rheumatoid Arthritis	Altered Intercellular Communication	In addition to traditional risk factors, excess cardiovascular disease (CVD) in rheumatoid arthritis (RA) is attributed to enhanced vascular and/or systemic inflammation.	28992382
Refractory anemias, Inflammation, Miller Dieker syndrome	Altered Intercellular Communication	RA patients underwent cardiac FDG-PET/CT, with aortic inflammation assessed by quantification of FDG uptake in the ascending aorta, calculated as the mean and maximum (max) standardized uptake value (SUV) of the entire ascending aorta and of its most diseased segment (SUV MDS).	28992382
Inflammation, Genus staphylococcus, Demographics Domain	Altered Intercellular Communication	Staphylococcus and chronic hemodialysis were more prevalent in patients with DM, and these patients had greater preoperative inflammation levels and worse renal function than patients without DM.	28992971
Airway structure, Wheezing	Altered Intercellular Communication	Recurrent wheeze and its relationship with lung function and airway inflammation in preschool children: a cross-sectional study in South Korea.	28993393
Inflammation, Wheezing	Altered Intercellular Communication	Relationship between recurrent wheeze and airway function and inflammation in preschool children is not fully known.	28993393
Asthma, AHR wt Allele, MS4A2 wt Allele	Altered Intercellular Communication	To investigate the relationship between recurrent wheeze and airway inflammation, lung function, airway hyper-reactivity (AHR) and atopy in preschool children.	28993393
Airway structure, Wheezing, AHR wt Allele, MS4A2 wt Allele	Altered Intercellular Communication	Recurrent wheeze in preschool children may be associated with airway inflammation and diminished airway function, but not with AHR or atopy.	28993393
Inflammation, Disease	Altered Intercellular Communication	Levels of proinflammatory (TNF A) and anti-inflammatory (IL-10) cytokines play a key role in the progression of inflammation as well as cancer disease.	28993831
Inflammation, Infection, Chronic disease, Fatigue	Altered Intercellular Communication	Systemic inflammation may play a role in the development of idiopathic fatigue, that is, fatigue not explained by infections or diagnosed chronic illness, but this relationship has never been investigated in community studies including the entire adult age span.	28994356
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Five patients showed inflammation in joints pre-damaged by osteoarthritis.	29018908
Inflammation, Fracture	Altered Intercellular Communication	While diet is a potential source of inflammation, little is known about the impact of inflammatory diet on fractures.	29018920
Inflammation, Retinitis Pigmentosa, polychondritis	Altered Intercellular Communication	Relapsing polychondritis (RP) is a rare collagen disease characterized by inflammation and destruction of cartilage throughout the body.	29019876
Inflammatory abnormality of the eye, Arthritis, Chondritis of pinna, Retinitis Pigmentosa	Altered Intercellular Communication	Based on the auricle biopsy results and the three presenting symptoms (bilateral auricular chondritis, inflammatory arthritis and ocular inflammation), her condition was diagnosed as RP.	29019876
Inflammation, Metabolic Syndrome X, MS gene	Altered Intercellular Communication	Leptin and adiponectin have opposite effects on subclinical inflammation and insulin resistance, both involved in the development of metabolic syndrome (MS).	29020116
Intraocular inflammation	Altered Intercellular Communication	Worse initial visual acuity and severe intraocular inflammation at first presentation were equally associated with poor visual outcome in the multivariate model (adjusted odds ratio, 20.32; 95% confidence interval [1.12-357.45]; P = 0.040).	29020471
Intraocular inflammation	Altered Intercellular Communication	Poor initial visual acuity and severe intraocular inflammation at the initial presentation are predictors of poor visual outcome.	29020471
Inflammation, Hemorrhage, Specimen Reject Reason - Clotting	Altered Intercellular Communication	Histologic evaluation demonstrated complete endothelial coverage of the device by 30 days without evidence of bleeding, clotting, or inflammation.	29020709
Diabetic Nephropathy, Tumor necrosis, Nephritis	Altered Intercellular Communication	Consequently, hEC-SOD recovered from systemic and renal inflammation and apoptosis, as reflected by the decreases of serum and renal monocyte chemoattractant protein-1 and tumor necrosis factor-a levels and increases of BCL-2/BAX ratio in diabetic kidney.	29020797
Inflammation, Primary malignant neoplasm, Diarrhea, Bothered by Vomiting, Gastrointestinal mucositis, Abdominal Pain, Nausea	Altered Intercellular Communication	Although these forms of treatment damage rapidly dividing cancer cells, they are also toxic to the cells of the gastrointestinal tract, leading to inflammation of the mucosal layer (mucositis) and causing nausea, vomiting, diarrhea, and abdominal pain.	29020798
Suppurative inflammation	Altered Intercellular Communication	His first presentation showed moderate intracameral and intravitreous purulent inflammation with a best corrected vision of counting fingers.	29020920
Inflammation, Obesity	Altered Intercellular Communication	Limited data on whether physical activity modulates inflammatory status and counteracts obesity and insulin resistance associated low-grade inflammation exist.	29020958
Lymphoid Tissue, Inappropriate ADH Syndrome	Altered Intercellular Communication	Syndrome of Inappropriate Antidiuretic Hormone Secretion in a Patient with Mucosa-associated Lymphoid Tissue Lymphoma.	29021471
Inflammation, Arthritis	Altered Intercellular Communication	Microflow imaging: New Doppler technology to detect low-grade inflammation in patients with arthritis.	29022101
Inflammation, Arthritis	Altered Intercellular Communication	To assess the efficacy of microvascular imaging in detecting low-grade inflammation in arthritis compared with Power Doppler ultrasound (PDUS).	29022101
Inflammation, Arthritis	Altered Intercellular Communication	This allows detection of low grade inflammation not visualised with Power Doppler in patients with arthritis.	29022101
Inflammation	Altered Intercellular Communication	* SMI can detect low-grade inflammation not seen with Power Doppler.	29022101
Inflammation, unencapsulated part of cell	Altered Intercellular Communication	The density of lymphatic vessels and gene expressions related to lymphatic vessel, inflammation and proliferation were increased in non-encapsulated lipoma.	29022421
Inflammation, Thrombosis	Altered Intercellular Communication	In protocol 1, we evaluated markers of inflammation, thrombosis, and conduit artery endothelial function in subjects on non-ATV containing regimens.	29023508
Anxiety, CTCAE 3.0, Epilepsy	Altered Intercellular Communication	GABAergic neurotransmission in the amygdala contributes to the regulation of emotional processes in anxiety, stress, reward, mnestic functions, addiction, and epilepsy.	29023704
Xanthogranulomatous inflammation, IgG4-Related Sclerosing Disease	Altered Intercellular Communication	XGCs with IgG4-positive cell infiltration are considered to be mimickers, as xanthogranulomatous inflammation generally contradicts a diagnosis of IgG4-related disease and is weakly associated with other typical organ manifestations of IgG4-related disease.	29023932
Inflammation, Osteitis	Altered Intercellular Communication	Maxillo-facial CT and MRI showed inflammation of soft tissues and muscles without initial signs of osteitis, thus noncontributive to the diagnosis.	29024750
Dental Plaque	Altered Intercellular Communication	Our data suggests that other pathways than the inflammation-pathway are involved in plaque vulnerability and poor outcome in patients with decreased kidney function.	29024865
Hyperglycemia, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	The anti-inflammatory function of HDL is impaired in type 2 diabetes: role of hyperglycemia, paraoxonase-1 and low grade inflammation.	29025405
Hyperglycemia, Inflammation	Altered Intercellular Communication	The HDL anti-inflammatory capacity is substantially impaired in T2DM, at least partly attributable to the degree of hyperglycemia, decreased PON-1 activity and enhanced low grade chronic inflammation.	29025405
ARCN1 gene, Inflammation	Altered Intercellular Communication	Impact and associations of eosinophilic inflammation in COPD: analysis of the AERIS cohort.	29025891
ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease	Altered Intercellular Communication	Eosinophilic inflammation in chronic obstructive pulmonary disease (COPD) predicts response to treatment, especially corticosteroids.	29025891
ARCN1 gene, Inflammation, Exacerbation	Altered Intercellular Communication	We studied the nature of eosinophilic inflammation in COPD prospectively to examine the stability of this phenotype and its dynamics across exacerbations, and its associations with clinical phenotype, exacerbations and infection.127 patients aged 40-85 years with moderate to very severe COPD underwent repeated blood and sputum sampling at stable visits and within 72 h of exacerbation for 1 year.Blood eosinophils >=2% was prevalent at baseline, and predicted both predominantly raised stable-state eosinophils across the year (area under the curve 0.841, 95% CI 0.755-0.928) and increased risk of eosinophilic inflammation at exacerbation (OR 9.16; p<0.001).	29025891
ARCN1 gene, Bacterial Infections, Eosinophilic inflammation	Altered Intercellular Communication	Bacterial infection at exacerbation was highly seasonal (winter versus summer OR 4.74; p=0.011) in predominantly eosinophilic patients.Eosinophilic inflammation is a common and stable phenotype in COPD.	29025891
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In non-inflamed UC (QUC) keratins, vimentin, and focal adhesion kinase (7) increased, whereas vinculin and de-tyrosinated a-tubulin decreased; inflammation (IUC) exacerbated molecular changes, being collagen type VI alpha 1 chain (COL6A1), tenascin-C and vimentin increased.	29027377
Refractory anemias, Inflammation	Altered Intercellular Communication	RA patients with positive anti-CCP antibodies had higher degrees of inflammation and disease activity as indicated by laboratory results, which likely contributed to their higher rates of healthcare utilization, joint erosion, and proportions of RA treatment.	29027497
TNF protein, human, Inflammation, Psoriasis vulgaris	Altered Intercellular Communication	Elevated levels of the biomarkers of inflammation (TNF-a, CRP, and IL-6) and the indicators of apoptosis (cfDNA, circulating nucleosomes) proved that exacerbated psoriasis vulgaris is associated with a high degree of systemic inflammatory responses and dysregulated apoptotic pathways.	29027583
Inflammation, Pustular psoriasis	Altered Intercellular Communication	Based on recent experimental data on the biology of ZIKV infection in the cutaneous environment, we speculate that ZIKV may have directly triggered the development of generalized pustular psoriasis by stimulation of keratinocyte-derived mediators of inflammation and a polyfunctional T-cell driven immune reaction in the cutaneous milieu.	29027743
Inflammation, Endocrine System Diseases	Altered Intercellular Communication	Inflammation and endocrine disorders are considered as major pathogenic factors of coronary atherosclerotic disease (CAD).	29028483
Inflammation, Nephritis, ENL Protein, Neuritis, Osteitis, Skin lesion, Lymphadenitis, Dactylitis, Arthritis, Orchitis	Altered Intercellular Communication	ENL is associated with clinical features such as skin lesions, neuritis, arthritis, dactylitis, eye inflammation, osteitis, orchitis, lymphadenitis and nephritis.	29028793
Colitis	Altered Intercellular Communication	Furthermore, BGM and EL-NE biomarkers were highly associated with colon inflammation in CD patients.	29028807
Inflammation	Altered Intercellular Communication	Formation of type V collagen is related to the level of inflammation in CD and may reflect disease activity in CD.	29028807
Metabolic Syndrome X	Altered Intercellular Communication	Electronegative Low-Density Lipoprotein L5 Induces Adipose Tissue Inflammation Associated With Metabolic Syndrome.	29029093
Inflammation	Altered Intercellular Communication	To investigate the role of L5 in the mechanism of adipose tissue inflammation associated with MetS.	29029093
Inflammation	Altered Intercellular Communication	L5 induces adipose inflammation through LOX-1 by promoting macrophage maturation and infiltration into adipose tissue.	29029093
vascular inflammations, Sleep Apnea, Obstructive, Coronary Artery Disease, Osage language	Altered Intercellular Communication	Obstructive sleep apnea (OSA) and enhanced vascular inflammation coexist in patients with coronary artery disease (CAD).	29029237
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Liver parenchyma adjacent to the treated lesion showed inflammation followed by fibrosis, without significant change in hepatic function.	29029891
Inflammation, Musculoskeletal Pain	Altered Intercellular Communication	Whole-body cryotherapy (WBC), which consists of a short exposure to very cold and dry air in special 'cryo-chambers', is believed to reduce inflammation and musculoskeletal pain as well as improve athletes' recovery.	29030365
Inflammation	Altered Intercellular Communication	MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ Damage.	29030400
Inflammation, Damage	Altered Intercellular Communication	Our results highlight smoking-associated microRNAs and are consistent with the hypothesis that smoking-associated microRNAs serve as mediators of smoking-induced inflammation and target organ damage.	29030400
Inflammation, Fatty infiltration	Altered Intercellular Communication	TIRM hyperintense areas, suggesting inflammation, were found in 3.5% of all muscles, with and without fatty infiltration.	29030457
Synapses, "Alzheimers Disease	Altered Intercellular Communication	We show that downregulation of RBFOX1 leads to destabilization of mRNAs encoding for synaptic transmission proteins, which may contribute to the loss of synaptic function in Alzheimer's disease.	29030541
Inflammation	Altered Intercellular Communication	Together, our results demonstrated that CD bacteria could promote Th1/Th17 inflammation in a host factor-independent fashion.	29031634
Inflammation	Altered Intercellular Communication	Chronic inflammation is an important component of intervertebral disc (IVD) degeneration, but there is limited knowledge about the identity and source of inflammatory cells involved with the degenerative processes.	29031872
Deficit, Inflammation	Altered Intercellular Communication	Elderly residents of long-term care commonly exhibit a number of age-related health deficits, including impaired physical and cognitive function, chronic illnesses, and chronic inflammation.	29032243
Inflammation, Psychiatric	Altered Intercellular Communication	Although aberrant expression of cytokines such as IL-1B and IFNG in blood from psychiatric patients supports a role of inflammation in the pathogenesis of the disease, little is known about mechanisms underlying their regulation.	29032575
Seizures, Inflammation, Disease	Altered Intercellular Communication	Our data shed further light on the potential role of inflammation, and more particularly inflammatory lncRNAs, in SZ and BP diseases and their pharmacological treatment.	29032575
Granulomatous inflammation, Neoplasms	Altered Intercellular Communication	Only one GCT had a diameter of <5 mm, and this was a regressed tumour within an 18-mm area of granulomatous inflammation.	29032579
Blepharitis, Inflammation, Corneal Infection	Altered Intercellular Communication	Age was a significant factor to be a case of corneal infection or inflammation [Exp (B)was 0.918, p=0.030], MGD and blepharitis was found to be significantly associated with being a case of SPK [Exp(B)was2.276, p=0.047].	29033270
Pleurisy, Pseudotumor, Autoimmune Chronic Hepatitis	Altered Intercellular Communication	IgG4-related Lung Pseudotumor and Pleural Inflammation with Autoimmune Hepatitis.	29033427
Pleurisy, Autoimmune Chronic Hepatitis, Biopsy of pleura (procedure)	Altered Intercellular Communication	After pleural and liver biopsy procedures, he was conclusively diagnosed with IgG4-related lung pseudotumor and pleural inflammation with autoimmune hepatitis.	29033427
Inflammation, Bipolar Disorder	Altered Intercellular Communication	There is a large extant literature on the association between depressive symptoms and inflammation.	29034558
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Temperament provides a more robust predictor of later inflammation than depressive symptoms.	29034558
Steatohepatitis, Inflammation	Altered Intercellular Communication	The outcome variables of interest were indicators of hepatic steatosis, liver enzymes, insulin resistance, inflammation and oxidative stress.	29035092
Primary malignant neoplasm, Catheter-Related Inflammation	Altered Intercellular Communication	C-C motif chemokine ligand 18 (CCL18) was reported as a chemokine-mediated tumor-related inflammation that can be detected in serum and may correlate with cancer patients' prognosis.	29036787
Inflammation	Altered Intercellular Communication	These patients have elevated oxidative stress and chronic inflammation.	29036910
Muscle damage, Inflammation, Pain Distress Question	Altered Intercellular Communication	We analyzed postoperative serum makers for muscle damage and inflammation, postoperative surgical pain, and performance status.	29037186
Inflammation	Altered Intercellular Communication	The location of involvement in the upper third of SI is insufficient to differentiate between degeneration and inflammation.	29037308
Inflammation, Systemic Scleroderma	Altered Intercellular Communication	Pulmonary magnetic resonance imaging is similar to chest tomography in detecting inflammation in patients with systemic sclerosis.	29037314
Pelvic Inflammatory Disease	Altered Intercellular Communication	Abdominal and pelvic imaging showed uterine and adnexal inflammation, and pelvic examination confirmed a diagnosis of pelvic inflammatory disease.	29037929
Inflammation, "Alzheimers Disease", neuron death, Data types - Address	Altered Intercellular Communication	Amyloid-b peptide (Ab) initiates a cascade of pathological events, including activation of microglial cells, oxidative stress, and inflammation, leading to neuronal death and the typical pathological changes in Alzheimer's disease (AD).	29038004
Inflammation, Impaired cognition	Altered Intercellular Communication	These results demonstrate that FLDK alleviates cognitive decline and reduces Ab burden, microglial activation, oxidative stress, and inflammation responses.	29038004
Inflammation	Altered Intercellular Communication	Young African females are at an increased risk of HIV acquisition, and genital inflammation or the vaginal microbiome may contribute to this risk.	29038128
Inflammation	Altered Intercellular Communication	Unsupervised clustering of 16S rRNA gene sequences revealed three clusters (subtypes), one of which was strongly associated with genital inflammation.	29038128
Inflammation	Altered Intercellular Communication	In a multivariate model, the microbiome compositional subtype and hormonal contraception were significantly associated with genital inflammation.	29038128
Inflammation, Aerococcus, Gemella, Sneathia, Genus Fusobacterium	Altered Intercellular Communication	We identified 40 taxa significantly associated with inflammation, including those reported previously (Prevotella, Sneathia, Aerococcus, Fusobacterium, and Gemella) as well as several novel taxa (including increased frequencies of bacterial vaginosis-associated bacterium 1 [BVAB1], BVAB2, BVAB3, Prevotella amnii, Prevotella pallens, Parvimonas micra, Megasphaera, Gardnerella vaginalis, and Atopobium vaginae and decreased frequencies of Lactobacillus reuteri, Lactobacillus crispatus, Lactobacillus jensenii, and Lactobacillus iners).	29038128
Bacterial Vaginosis, Inflammation	Altered Intercellular Communication	Community functional profiling revealed three distinct vaginal microbiome subtypes, one of which was characterized by extreme genital inflammation and persistent bacterial vaginosis (BV); this subtype could be predicted with high specificity and sensitivity based on the Nugent score (>=9) or BVAB1 abundance.	29038128
Acute and chronic inflammation, HIV Infections	Altered Intercellular Communication	We propose that women with this BVAB1-dominated subtype may have chronic genital inflammation due to persistent BV, which may place them at a particularly high risk for HIV infection.	29038128
Inflammation	Altered Intercellular Communication	In a multivariate model, the microbiome compositional subtype and hormonal contraception were significantly associated with genital inflammation.	29038128
Inflammation	Altered Intercellular Communication	As low-grade inflammation and increased plasma ferritin concentration are associated with all-cause mortality, we hypothesized that increased plasma ferritin concentration is genetically associated with low-grade inflammation.	29038157
Inflammation, Familial Mediterranean Fever, Autosomal recessive inheritance, Brucellosis	Altered Intercellular Communication	Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurrent episodes of painful inflammation in the abdomen, chest, or joints.	29038396
Inflammation, Anomia, Impaired cognition, "Alzheimers Disease	Altered Intercellular Communication	Systemic Inflammation and Multimodal Biomarkers in Amnestic Mild Cognitive Impairment and Alzheimer's Disease.	29039020
Inflammation, Data types - Address	Altered Intercellular Communication	However, the role of systemic inflammation in AD pathophysiology is much less understood.	29039020
Inflammation, Hippocampal atrophy, Data types - Address	Altered Intercellular Communication	Our findings indicate a possible relationship between systemic inflammation with DMN FC disruption, hippocampal atrophy, and CSF protein levels in the subjects with mild AD and aMCI.	29039020
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Formyl peptide receptor 2 (FPR2) has been identified as a member of the G protein-coupled chemoattractant receptor (GPCR) family and has been implicated as playing a role in both inflammation and cancer development.	29039544
Communicable Diseases, ovarian neoplasm, Inflammation	Altered Intercellular Communication	Epithelial ovarian cancer (EOC) has been suggested to be correlated with both infectious and non-infectious inflammation.	29039544
Inflammation, Metabolic Syndrome X, Obesity	Altered Intercellular Communication	Central obesity is associated with chronic low-grade inflammation, and is a risk factor for cardiometabolic syndrome.	29039967
Inflammation, Thrombosis, Moist	Altered Intercellular Communication	Platelets express high-mobility group box 1 (HMGB1), a damage-associated molecular pattern molecule (DAMP) that triggers thrombosis and inflammation when present in extracellular space.	29041001
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	The precise mechanism linking systemic inflammation with insulin resistance (IR) in rheumatoid arthritis (RA) remains elusive.	29041949
Islet Cell Tumor	Altered Intercellular Communication	Various inflammation-based prognostic scores have been associated with reduced survival in patients with nonfunctional pancreatic neuroendocrine tumor (NF-PNET).	29042631
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Identification of such modified proteins in inflamed gingiva may explain, in part, how inflammation of the periodontal tissues may influence the development of rheumatoid arthritis.	29044530
Inflammation, Blood Glucose	Altered Intercellular Communication	However, we found significant between-group differences in other markers of insulin resistance (HbA1c, glycemia, HOMA-IR) and inflammation.	29045090
Hypotensive, Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Chronic use of topical hypotensive therapies in glaucoma patients leads to chronic inflammation of the ocular surface, which decreases the success rate of long-term glaucoma management.	29045169
Glaucoma, Primary Open Angle, Inflammatory abnormality of the eye	Altered Intercellular Communication	Our data suggests that topical PEA (Defluxa) is a safe, effective, and generally well-tolerated treatment to prevent or suppress ocular surface inflammation attributable to chronic glaucoma treatment.	29045169
Colitis, Gastrointestinal inflammation, Pseudo-obstruction of gastrointestinal tract	Altered Intercellular Communication	Four distinct categories of GI-irAE were observed: acute colitis (n = 8, 40%), microscopic colitis (n = 7, 35%), upper gastrointestinal tract inflammation (n = 4, 20%) and pseudo-obstruction (n = 1, 5%).	29045560
Gastrointestinal inflammation, Colitis	Altered Intercellular Communication	Response rates to corticosteroids were 87.5% (7/8) in acute colitis, 57% (4/7) in microscopic colitis and 75% (3/4) in upper gastrointestinal tract inflammation.	29045560
Inflammation, Myocardial, Heart failure	Altered Intercellular Communication	Antibodies to receptors are associated with biomarkers of inflammation and myocardial damage in heart failure.	29046223
Inflammation, Tissue injury, Heart failure	Altered Intercellular Communication	Naturally occurring antibodies are linked to inflammation, tissue injury and apoptosis, processes also linked to heart failure.	29046223
Inflammation, Myocardial, Heart failure	Altered Intercellular Communication	Associations between antibodies, inflammation and myocardial damage, have not been elucidated in heart failure.	29046223
Inflammation, Heart failure	Altered Intercellular Communication	We investigated if 25 antibodies to receptors expressed in the cardiovascular system were associated with troponin-T, biomarkers of inflammation and clinical measures of disease severity, in patients with heart failure.	29046223
Inflammation, Myocardial, Heart failure	Altered Intercellular Communication	Antibodies to receptors are correlated and are associated with biomarkers of inflammation and myocardial damage, which further modifies their association with disease severity in heart failure.	29046223
Inflammation	Altered Intercellular Communication	Free circulating active elastase contributes to chronic inflammation in patients on hemodialysis.	29046295
Inflammation, Blood Vessel	Altered Intercellular Communication	This study tested the hypothesis that in states of noninfectious inflammation, elastase is released by PMNLs and acts in an uncontrolled manner to inflict vascular damage.	29046295
Inflammation, Diabetic Angiopathies	Altered Intercellular Communication	In addition, it suggests that free circulating elastase can serve as a new biomarker and therapeutic target to reduce inflammation and vascular complications in patients on hemodialysis.	29046295
Inflammation	Altered Intercellular Communication	Biological aging is associated with immune activation (IA) and declining immunity due to systemic inflammation.	29046481
Inflammation, Lung diseases	Altered Intercellular Communication	Such vascular remodeling can be associated with inflammation, shear stress, and hypoxia-conditions commonly seen in patients with lung diseases.	29047102
Inflammation, Pleural Effusion, Malignant, Carcinogenesis, Fibrosis Assessment, Pleural Effusion, CTCAE	Altered Intercellular Communication	Highly expressed proteins in malignant pleural effusion were associated with carcinogenesis and cell growth, and proteins associated with tuberculous pleural effusion played a role in the response to inflammation and fibrosis.	29047238
methyldopa, Inflammation	Altered Intercellular Communication	While inflammation seems to be continuously stimulated by RPE associated with late exudative AMD, this appears not to be the case with regard to angioregulatory mechanisms.	29050001
Chronic lymphocytic inflammation, Pontine structure, Clippers	Altered Intercellular Communication	Diagnostic criteria for chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS).	29050399
Chronic lymphocytic inflammation, Pontine structure, Clippers	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a central nervous system inflammatory syndrome predominantly affecting the brainstem, cerebellum, and spinal cord.	29050399
Inflammation, Cardiac fibrosis, Eating, Obesity	Altered Intercellular Communication	Inflammation and obesity are associated with cardiac fibrosis, but the relationship between cardiac fibrosis and EAT is unknown.	29050981
Necrotizing granulomatous inflammation, Orbital Cellulitis	Altered Intercellular Communication	A rare case of orbital granulomatous inflammation from explosive hydraulic oil masquerading as orbital cellulitis.	29053030
Acute inflammation of orbit	Altered Intercellular Communication	The differential diagnosis for acute orbital inflammation is broad.	29053030
Necrotizing granulomatous inflammation, Orbital Cellulitis	Altered Intercellular Communication	We report a case of granulomatous orbital inflammation due to high-pressure oil injury to the orbit presenting as an atypical orbital cellulitis.	29053030
Orbital Pseudotumor	Altered Intercellular Communication	Here we review the presentation and treatment of orbital inflammation from oil.	29053030
Cystic Lesion, Inflammation, Odontogenic Tumors, Bone Diseases, Odontogenic Cysts	Altered Intercellular Communication	The histological diagnosis were grouped into the categories Cystic lesions of odontogenic origin, Periapical inflammation, Odontogenic tumors, Bone diseases, Health tissue and Nonspecific diagnostic.	29053654
Cystic Lesion, Inflammation, Odontogenic Cysts, Pathology	Altered Intercellular Communication	More than half of pathologies were cystic lesions of odontogenic origin (822/51.4%), followed by periapical inflammation (282/17.6%).	29053654
Inflammation, square decimeter, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Obesity and diabetes mellitus type 2 (DM2) are characterized by chronic inflammation and oxidative stress [Donath et al.	29053995
Inflammation	Altered Intercellular Communication	An increase in glutathione peroxidase, a decrease in uric acid and no change in glutathione reductase, total antioxidant status, oxidative damage, inflammation and glucose markers were found.	29053995
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The enzyme indoleamine 2,3-dioxygenase (IDO) is emerging as a facilitator of cancer development through its effects on cancer-associated inflammation.	29054599
Cessation of life, Mortality, Premature, Chronic disease	Altered Intercellular Communication	The main idea is that there is a common pathway from wellbeing and health to chronic disease ("chronopathy") and even to death, which comprises following steps: 1) unhealthy diet, sedentary life style and permanent exposition to xenobiotics and all kinds of noxious stimuli;-2) intestinal dysbiosis;-3) alteration of the intestinal mucus layer (especially that of the colon);-4) disruption of the endothelial tight junctions;-5) metabolic endotoxemia+bacterial translocation;-6) inflammation;-7) exacerbation of the enteric nervous system (ENS) and consequent maladaptation and malfunctioning of the colon;-8) epigenetic manifestations;-9) "chronopathy" and premature death.	29055387
Chronic lymphocytic inflammation, Pontine structure, Clippers	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS): A pediatric case report with six year follow-up.	29055484
Chronic lymphocytic inflammation, Pontine structure, Clippers, Inflammatory disorder	Altered Intercellular Communication	Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disorder involving brainstem, pons in particular, characterized by a predominant T-cell pathology and responsiveness to glucocorticosteroids.	29055484
Inflammation, mecarzole	Altered Intercellular Communication	Items of a GA and biomarkers of inflammation and nutrition may have prognostic significance in patients with MBC.	29055624
Psoriasis	Altered Intercellular Communication	Visceral Adiposity in Psoriasis is Associated With Vascular Inflammation by 18F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography Beyond Cardiometabolic Disease Risk Factors in an Observational Cohort Study.	29055628
vascular inflammations, Psoriasis	Altered Intercellular Communication	The authors sought to examine the relationship between visceral adipose tissue (VAT) and vascular inflammation (VI) by 18F-Fluorodeoxyglucose (18F-FDG) positron-emission tomography (PET)/computed tomography (CT) in psoriasis (PSO).	29055628
Steatohepatitis, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Inflammation	Altered Intercellular Communication	Bariatric surgery in eligible morbidly obese individuals may improve liver steatosis, inflammation, and fibrosis; however, population-based data on the clinical benefits of bariatric surgery in patients with nonalcoholic fatty liver disease (NAFLD) are lacking.	29055669
Inflammation, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	The prognostic value of inflammation indexes in non small cell lung cancer (NSCLC) was not established.	29057536
Small cell carcinoma of lung	Altered Intercellular Communication	Our results demonstrated that F-NLR, a novel inflammation-based grading system, as well as the GPS, appeared to have value as a promising clinical predictor of the prognosis for the resectable non small cell lung cancer patients.	29057536
Inflammation, Hypopigmentation disorder	Altered Intercellular Communication	Acquired skin hypopigmentation has many etiologies, including autoimmune melanocyte destruction, skin aging, inflammation, and chemical exposure.	29057565
Inflammation, Renal function, Chronic Kidney Diseases	Altered Intercellular Communication	The markers of inflammation, monocyte activation, and impaired kidney function were also increased in those with CKD.	29058166
Abducens Nerve Diseases, Postoperative Hemorrhage, Inflammation, Ischemic peripheral neuropathy	Altered Intercellular Communication	Our two cases of Abducens palsy following reoperative orbital decompression may be due to ischemic neuropathy caused by postoperative hemorrhage or inflammation.	29058517
Inflammation	Altered Intercellular Communication	The two scales are coupled because the immune response causes inflammation and adaptation, which affects the biomechanical parameters of the tissue such as his elasticity.	29060459
Inflammation	Altered Intercellular Communication	During repeated inflammation and breathing cycles, the tissue weakens and breaks down.	29060459
Delirium, Inflammation	Altered Intercellular Communication	We used C-reactive protein (CRP) as a pathophysiologic marker of inflammation, previously associated with delirium.	29061098
Inflammation, Lung, Tuberculosis	Altered Intercellular Communication	Chronic inflammation, possibly exacerbated by cigarette smoking, is considered to be the primary cause of pulmonary damage in patients with tuberculosis (TB).	29062328
Pseudomyxoma Peritonei, Neoplasms	Altered Intercellular Communication	The neutrophil-lymphocyte ratio (NLR) and other inflammation-based scores have been used as a prognostic tool to predict survival in solid tumours including pseudomyxoma peritonei (PMP).	29063804
Inflammation, Squamous cell carcinoma	Altered Intercellular Communication	High-risk squamous cell carcinoma masquerading as dense inflammation on Mohs frozen sections.	29064089
Inflammation	Altered Intercellular Communication	This case report describes how high-risk SCC may masquerade as only a dense inflammation on frozen sections.	29064089
Inflammation, Cerebral Hemorrhage	Altered Intercellular Communication	Assessing Inflammation in Acute Intracerebral Hemorrhage with PK11195 PET and Dynamic Contrast-Enhanced MRI.	29064155
Inflammation, Neoplasm Metastasis, COL4A2 wt Allele, Cerebral Hemorrhage	Altered Intercellular Communication	Studies in animal models suggest that inflammation is a major contributor to secondary injury after intracerebral hemorrhage (ICH).	29064155
Inflammation, COL4A2 wt Allele	Altered Intercellular Communication	Direct, noninvasive monitoring of inflammation in the human brain after ICH will facilitate early-phase development of anti-inflammatory treatments.	29064155
Inflammation, Heart failure	Altered Intercellular Communication	Previous studies have indicated a correlation between heart failure, inflammation and poorer outcome.	29064269
Inflammation, Acute heart failure, F8 wt Allele	Altered Intercellular Communication	However, the pathogenesis and role of inflammation in acute heart failure (AHF) is incompletely studied and understood.	29064269
Inflammation	Altered Intercellular Communication	Elevated leukocyte count as a harbinger of systemic inflammation, disease progression, and poor prognosis: a review.	29064542
Communicable Diseases, Inflammation, Traumatic injury	Altered Intercellular Communication	Total leukocyte count increases significantly in response to infection, trauma, inflammation, and certain diseases.	29064542
Inflammation	Altered Intercellular Communication	Recent findings suggest that elevated leukocyte count within the normal range, but especially neutrophil and monocyte counts, may be a harbinger of increased systemic inflammation and subclinical disease.	29064542
Inflammation	Altered Intercellular Communication	This review summarises the most important findings on the links between leukocyte count, chronic systemic inflammation, and health outcomes in older adults.	29064542
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Differences in the association of inflammation and tryptophan with depressive symptoms between white and non-white chronic dialysis patients.	29065338
Amyotrophic Lateral Sclerosis, Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative motor neuron disease accompanied by both systemic and central nervous system-specific inflammation as well as deregulated energy metabolism.	29065369
Presenile dementia, "Alzheimers Disease", Brain Diseases, Data types - Address	Altered Intercellular Communication	Alzheimer's disease (AD) is a progressive, neurodegenerative brain disorder that attacks neurotransmitters, brain cells, and nerves, affecting brain functions, memory, and behaviors and then finally causing dementia on elderly people.	29065619
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Changes in clinical disease activity are weakly linked to changes in MRI inflammation on treat-to-target escalation of therapy in rheumatoid arthritis.	29065903
Inflammation	Altered Intercellular Communication	We compared changes in the DAS28CRP with changes in magnetic resonance imaging (MRI) inflammation on treatment escalation.	29065903
Inflammation	Altered Intercellular Communication	Scan pairs were scored for inflammation (MRI(i)) and damage.	29065903
Refractory anemias, Inflammation	Altered Intercellular Communication	We report the first study investigating the link between changes in clinical and imaging inflammation in a real-world RA cohort escalating to conventional and biologic DMARDs.	29065903
Intestinal dysbiosis, Gastrointestinal inflammation	Altered Intercellular Communication	Severe intestinal dysbiosis is a prevalent finding in pSS and is associated both with clinical and laboratory markers of systemic disease activity as well as gastrointestinal inflammation.	29065905
Inflammation, Hereditary, Arthropathy	Altered Intercellular Communication	Ultrasound verified inflammation and structural damage in patients with hereditary haemochromatosis-related arthropathy.	29065925
palladium, Inflammation	Altered Intercellular Communication	Inflammation was also common in HH-WA, yielding GSS in 83.3% and PD signals in 50.0% of patients.	29065925
Inflammation, Cartilage damage	Altered Intercellular Communication	A high prevalence of ultrasound-verified inflammation and cartilage damage was found in HH-A, and to a lesser extent in HH-WA.	29065925
Inflammation, Keratoconus	Altered Intercellular Communication	Langerhans cells were present in a significant number of subjects suggesting the possibility of inflammation in keratoconus.	29066264
Inflammation, Keratoconus	Altered Intercellular Communication	Based on the association of Langerhans cells with nerve parameters, we propose inflammation as the underlying cause for corneal nerve changes in keratoconus.	29066264
Airway structure, Asthma	Altered Intercellular Communication	We report the utility of combining lung sound analysis and fractional exhaled nitric oxide (FeNO) for phenotype classification of airway inflammation in patients with bronchial asthma.	29066290
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a key role in atherosclerosis, but the association between inflammatory biomarkers and clinical outcomes is less studied in this population.	29066452
Inflammation	Altered Intercellular Communication	Up-regulated expression of GPR109A may be an inflammatory consequence and the improvement of inflammation may down-regulate the expression of GPR109A in T2DM.	29066482
Inflammation, Amyloidosis	Altered Intercellular Communication	Intramyocardial inflammation predicts adverse outcome in patients with cardiac AL amyloidosis.	29067795
Inflammation, Amyloidosis	Altered Intercellular Communication	Patients suffering from amyloidosis revealed a significant poor prognosis with proof of intramyocardial inflammation in contrast to those without inflammation (log-rank P = 0.019).	29067795
Inflammation, Amyloidosis, Myocarditis	Altered Intercellular Communication	The detailed subgroup analysis showed that patients suffering from AL amyloidosis with intramyocardial inflammation have a significantly worse prognosis compared with AL amyloidosis without inflammation and ATTR with or without inflammation, respectively (log-rank P = 0.014, contingency Fisher's exact test, P = 0.008).	29067795
Senile cardiac amyloidosis, Inflammation, Amyloidosis, Myocarditis	Altered Intercellular Communication	Our study reports for the first time a high incidence (48.1%) of intramyocardial inflammation in a series of patients with EMB-proven cardiac amyloidosis and could show that in patients with AL amyloidosis, intramyocardial inflammation correlated significantly with increased mortality.	29067795
Amyloidosis, Myocarditis	Altered Intercellular Communication	Our data have a direct clinical impact because one can hypothesize that additional immunomodulating/anti-inflammatory treatment regimens in patients with biopsy-proven inflammation of heart muscle tissue could be beneficial for patients suffering from cardiac AL amyloidosis.	29067795
Hormone abnormality, Hyperparathyroidism, Chronic Kidney Diseases, HYPERPARATHYROIDISM, NEONATAL SEVERE	Altered Intercellular Communication	INTRODUCTION Secondary hyperparathyroidism (SHPT) is a common hormonal disorder associated with chronic kidney disease (CKD).	29067991
Inflammation, Asthma	Altered Intercellular Communication	Sputum TWEAK level also showed significant positive correlations with asthma severity (r = .358, P = .001) and control status (r = .470, P < .001), distinctively in subjects with NEA inflammation.	29068159
Airway structure	Altered Intercellular Communication	Airway TWEAK may play a role in small airway inflammation especially in children with non-eosinophilic asthma.	29068159
Inflammation, Hemorrhage, Necrosis	Altered Intercellular Communication	Histological examination of the vascular bundle showed an electrocautery injury of the arterial wall: transmural necrosis, acute inflammation, and hemorrhage.	29068812
Inflammation, Congenital heart disease	Altered Intercellular Communication	Infants with congenital heart disease frequently require cardiopulmonary bypass, which causes systemic inflammation.	29068910
Bursitis	Altered Intercellular Communication	Pes anserine (PA) bursitis is an inflammatory condition of the medial knee.	29069005
Inflammation, Cartilage destruction, polychondritis, Multiple System Atrophy, Retinitis Pigmentosa	Altered Intercellular Communication	Relapsing polychondritis (RP) is a multisystemic, progressive disease of unknown etiology characterized by recurrent inflammation and progressive cartilage destruction.	29069021
Retinitis Pigmentosa, Inflammatory disorder of cartilage	Altered Intercellular Communication	Based on our patient presentation, we suggest that RP should be suspected in any transplant recipient with cartilage inflammation, and that the Michet's clinical criteria and scintigraphy seem to be the best diagnostic tools for solid organ transplant recipients suspected of RP.	29069021
Chorioretinitis, Inflammatory abnormality of the eye	Altered Intercellular Communication	Syphilitic chorioretinitis should be included in differential diagnosis of any form of ocular inflammation.	29069031
Inflammatory abnormality of the eye, Disorder of the optic nerve, Uveitis	Altered Intercellular Communication	It is necessary to reiterate the importance of including syphilis uveitis as a differential diagnosis for any form of ocular inflammations, especially posterior uveitis and optic neuropathy.	29069031
ARCN1 gene, Communicable Diseases, Chlamydia, Inflammation	Altered Intercellular Communication	The association between serological features of chronic Chlamydia pneumoniae infection and markers of systemic inflammation and nutrition in COPD patients.	29069917
ARCN1 gene, Communicable Diseases, Inflammation, physiopathological	Altered Intercellular Communication	The aim of the study was to investigate the association between chronic C. pneumoniae infection and clinical features of COPD, markers of inflammation and metabolic dysfunction.	29069917
Hemorrhagic, Inflammation, Central retinal vessel vascular tortuosity, Aneurysm, Ruptured	Altered Intercellular Communication	These hemorrhagic lesions, for example, a ruptured pseudoaneurysm, are often treated by transarterial embolization (TAE), but prior intervention or surgery, inflammation, anatomic variants, and vessel tortuosity may render an endovascular approach challenging, time-consuming, and sometimes impossible.	29070606
Inflammation, Aortic Stiffness, Obesity, Diabetes Mellitus	Altered Intercellular Communication	The prevalence of blunted nocturnal BP dipping is higher in persons with obesity and diabetes, conditions that are also associated with elevated aortic stiffness and inflammation.	29070829
Inflammation, Aortic Stiffness, Obesity, Blood Glucose	Altered Intercellular Communication	Therefore, we hypothesized that elevated glycemia, inflammation and aortic stiffness would be inversely associated with the magnitude of nocturnal systolic BP dipping among middle-aged/older adults with obesity at high CVD risk.	29070829
Inflammation, Aortic Stiffness, Obesity	Altered Intercellular Communication	Twenty-four hour ambulatory BP monitoring, aortic stiffness (carotid-femoral pulse wave velocity, CF-PWV), hemoglobin A1c (HbA1c) and inflammation (C-reactive protein, CRP) were measured in 86 middle-aged/older adults with obesity and at least one other CVD risk factor (age 40-74 years; 34 male/52 female; body mass index=36.7+-0.5 kg m-2; HbA1c=5.7+-0.04%).	29070829
Inflammation	Altered Intercellular Communication	These data suggest that impaired long-term glycemic control and higher inflammation may contribute partly to blunted BP dipping in middle-aged/older adults with obesity-related prediabetes.	29070829
Herpes Zoster Ophthalmicus, Inflammatory abnormality of the eye	Altered Intercellular Communication	To analyze and compare the clinical profile of herpes zoster ophthalmicus (HZO) patients in a South Indian patient population aged <60 years and >=60 years and determine the risk factors for recurrence of ocular inflammation.	29072860
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Presence of diabetes mellitus, increased intraocular pressure(IOP) at the time of active inflammation, use of topical steroids and recurrences were significantly more common in group 1.	29072860
Inflammation, Insulitis, Neoplasms	Altered Intercellular Communication	To explore the biological significance of Ninj1, we generated a cohort of Ninj1-deficient mice and found that Ninj1+/- mice were prone to systemic inflammation and insulitis, but not to spontaneous tumors.	29073078
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Cardiovascular Diseases	Altered Intercellular Communication	Obesity promotes excessive inflammation, which is associated with senescence-like changes in visceral adipose tissue (VAT) and the development of type 2 diabetes (T2DM) and cardiovascular diseases.	29073165
Inflammation, Graft-vs-Host Disease	Altered Intercellular Communication	There is experimental evidence that coexisting inflammation aggravates aGVHD.	29074374
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Mucosal inflammation must be carefully monitored to improve the long-term outcomes of patients with inflammatory bowel diseases (IBD).	29074448
Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Only 6 PROMs (patient-reported global assessment, patient assessment of disease activity, mobile health index for Crohn's disease, mobile health index for ulcerative colitis, patient-reported outcome derived from the Mayo score, and the 6-point Mayo score) were validated as markers of IBD activity, using findings from endoscopy as the reference standard; these PROMs identified patients with mucosal inflammation with area under the curve values of 0.63-0.82.	29074448
Inflammation	Altered Intercellular Communication	RV568, a narrow-spectrum kinase inhibitor with p38 MAPK-a and -g selectivity, suppresses COPD inflammation.	29074542
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Neutrophil-lymphocyte ratio (NLR) is a hematological marker of systemic inflammation and several studies demonstrate an association between a higher NLR and a worse prognosis in many malignancies.	29076002
Malignant Neoplasms	Altered Intercellular Communication	Exosomal miRNAs that play an important role in cell-cell communication have attracted major attention as potential diagnostic and prognostic biomarkers for various cancers.	29076027
Inflammation, Growth	Altered Intercellular Communication	Other less frequent findings were non-specific inflammation and fungating growths in rectum.	29076685
Inflammation, Tuberculosis	Altered Intercellular Communication	Result of biopsy showed granulomatous inflammation confirming pelvic tuberculosis.	29076692
Inflammation, Traumatic, Neoplasms, Communicable Diseases, Otosclerosis, Meniere Disease, Cerebrovascular Disorders, MS gene	Altered Intercellular Communication	Cases with inflammation in the middle or inner ear; a retro cochlear tumor; autoimmune, infectious, functional, metabolic, neoplastic, traumatic, toxic, or vascular causes; Meniere's disease; otosclerosis; multiple sclerosis; and/or cerebrovascular diseases were excluded.	29076927
Inflammation, Tuberculosis	Altered Intercellular Communication	However, when the CNV development is not accompanied by clear signs of inflammation, the etiology can be missed, especially in countries nonendemic for tuberculosis.	29077184
Inflammatory Bowel Diseases, Inflammation	Altered Intercellular Communication	Epstein-Barr virus (EBV) has been associated with inflammation in the colon, particularly in patients with inflammatory bowel disease (IBD).	29078077
Colitis	Altered Intercellular Communication	Further studies are necessary to confirm this association and to clarify the role of EBV in MC and, more generally, in colonic inflammation.	29078077
Inflammation, Lung diseases	Altered Intercellular Communication	Exhaled breath condensate (EBC) has emerged as a noninvasive method for assessing inflammation in lung diseases.	29078843
ARCN1 gene, Inflammation	Altered Intercellular Communication	TNF-a and IL-1b in EBC are potential biomarkers for evaluating pulmonary function and inflammation in patients with COPD.	29078843
ARCN1 gene, Inflammation	Altered Intercellular Communication	Furthermore, lung-protective treatment is effective in reducing inflammation in patients with COPD.	29078843
Inflammation	Altered Intercellular Communication	The pleiotropic pro-inflammatory cytokine, macrophage migration inhibitory factor (MIF), represents an important link between chronic inflammation and tumorigenesis.	29079416
Inflammation, Scleroderma	Altered Intercellular Communication	Before commencing tocilizumab, there was evidence of significant systemic inflammation, and progressive sclerodermatous changes (physician global assessment [PGA] 7/10).	29079714
Obesity, prostatitis	Altered Intercellular Communication	Molecular correlates in urine for the obesity and prostatic inflammation of BPH/LUTS patients.	29080225
Obesity, Benign prostatic hypertrophy, prostatitis	Altered Intercellular Communication	Benign prostatic hyperplasia (BPH) is strongly associated with obesity and prostatic tissue inflammation, but the molecular underpinning of this relationship is not known.	29080225
Lower Urinary Tract Symptoms, Obesity, prostatitis	Altered Intercellular Communication	Here, we examined the association between urine levels of chemokines/adipokines with histological markers of prostate inflammation, obesity, and lower urinary tract symptoms LUTS in BPH patients.	29080225
Inflammation, prostatitis	Altered Intercellular Communication	CCL3 in 15 patients with moderate to severe grade inflammation was marginally associated with maximal CD20 infiltration (P = 0.09), whereas CCL3 was undetectable in men with mild prostate tissue inflammation.	29080225
Lymphocytic infiltration, prostatitis	Altered Intercellular Communication	Increased urine levels of CXCL-10, CCL5, and CCL3 were marginally associated with the scores for prostate tissue inflammation and lymphocytic infiltration.	29080225
Metabolic Diseases, prostatitis	Altered Intercellular Communication	Overall, elevated urinary chemokines support that BPH is a metabolic disorder and suggest a molecular link between BPH/LUTS and prostatic inflammation.	29080225
Inflammation, Muscle, Smooth, Vascular, In-Stent Restenosis Indicator	Altered Intercellular Communication	Increased serum TREM-1 level is associated with in-stent restenosis, and activation of TREM-1 promotes inflammation, proliferation and migration in vascular smooth muscle cells.	29080545
Inflammation	Altered Intercellular Communication	These data suggest that TREM-1 is a predictive biomarker of ISR and an important mediator of cellular inflammation, migration, and proliferation in VSMCs.	29080545
Non-insulin Hypoglycemic, Inflammation, Infection caused by Helicobacter pylori, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Male non-insulin users with type 2 diabetes mellitus are predisposed to gastric corpus-predominant inflammation after H. pylori infection.	29082856
precancerous lesions, Gastritis, Diabetes Mellitus, Non-Insulin-Dependent, Infection caused by Helicobacter pylori	Altered Intercellular Communication	This study investigated whether patients with type 2 diabetes mellitus (T2DM) and H. pylori infection had more severe corpus gastric inflammation and higher prevalence of precancerous lesions than non-diabetic controls.	29082856
Gastritis, Diabetes Mellitus, Non-Insulin-Dependent, Infection caused by Helicobacter pylori	Altered Intercellular Communication	Patients with type 2 diabetes mellitus and H. pylori infection had more severe corpus gastric inflammation than non-diabetic controls.	29082856
Chronic disease	Altered Intercellular Communication	Inflammatory conditions in the joint hamper the application of tissue engineering during chronic joint diseases.	29083361
Pneumonitis, CTCAE, Inflammation, Toxic effect, Cessation of life	Altered Intercellular Communication	Pneumonitis is defined as a focal or diffuse inflammation of the lung parenchyma, and is a known, potentially fatal toxicity of anti-programmed death 1 (PD-1)/programmed death ligand 1 (PD-L1) immune checkpoint inhibitors.	29083466
Inflammation, Photoreceptors	Altered Intercellular Communication	Cytokine stimulation of Muller glia resulted in production of NTs, and GDNF treatment reduced photoreceptor cell death in response to inflammation and oxidative stress.	29084332
Inflammation, Hypertension, CTCAE, Endothelial dysfunction	Altered Intercellular Communication	Inflammation and endothelial dysfunction may play an important role in the multifactorial pathogenesis of hypertension.	29084442
Inflammation, Stress Disorders, Traumatic	Altered Intercellular Communication	The Role of Inflammation in Late-Life Post-Traumatic Stress Disorder.	29087846
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	There is evidence that immune system dysregulation and inflammation may play a role in the development of post-traumatic stress disorder (PTSD).	29087846
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	However, it is unclear whether exacerbation of PTSD symptoms late in life is also associated with elevated inflammation.	29087846
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	The purpose of this pilot study was to examine the relationship between inflammation and late-life PTSD.	29087846
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	The results from this pilot study suggest that late-life PTSD may be associated with increased inflammation.	29087846
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	Further research in larger samples is needed to corroborate these findings and to clarify the relationship between inflammation and PTSD, which may lead to improved methods of diagnosis and treatment.	29087846
Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Systemic immune-inflammation index predicting chemoradiation resistance and poor outcome in patients with stage III non-small cell lung cancer.	29089030
Inflammation, Neoplasms	Altered Intercellular Communication	There is increasing evidence that the existence of systemic inflammation response is correlated with poor prognosis in several solid tumors.	29089030
Intrahepatic Cholangiocarcinoma, Cholangitis, Malignant Neoplasms	Altered Intercellular Communication	Intrahepatic cholangiocarcinoma (iCCA) represents a heterogeneous group of malignancies emerging from the biliary tree, often in the context of chronic bile ducts inflammation.	29089545
ARCN1 gene, Inflammation, Anemia, Diabetes Mellitus	Altered Intercellular Communication	Presence of COPD was associated with predominance of diabetes mellitus, interleukin-8-related systemic neutrophilic inflammation and anemia.	29089753
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The pathologic features of post-ischemic stricture were deep ulceration, submucosal/subserosal fibrosis and chronic transmural inflammation.	29089826
Inflammation, Secondary malignant neoplasm of skin, Congenital Abnormality, Refractory anemias, Rheumatoid Arthritis	Altered Intercellular Communication	Foot symptoms in rheumatoid arthritis (RA) derive from a combination of inflammation, altered foot mechanics, deformity and secondary skin lesions.	29090022
Inflammation, acute diverticulitis	Altered Intercellular Communication	Serum inflammation markers may help to differentiate severity of acute diverticulitis and predict the need for surgical intervention in clinical practice.	29091955
Pituitary microadenoma, Parathyroid Adenoma	Altered Intercellular Communication	Screening of other endocrine glands revealed pituitary microadenoma and parathyroid adenoma on imaging, which was also supported by biochemical and hormonal profile.	29092962
Inflammation	Altered Intercellular Communication	A regime of three boluses leads to a smaller decrease in the level of Hb, less post-operative inflammation and a shorter length of stay in hospital than a single bolus.	29092982
RANGAP1 wt Allele, Inflammation, "Alzheimers Disease	Altered Intercellular Communication	Each SD increase in midlife inflammation composite score was associated with 1,788 mm3 greater ventricular (p = 0.013), 110 mm3 smaller hippocampal (p = 0.013), 519 mm3 smaller occipital (p = 0.009), and 532 mm3 smaller Alzheimer disease signature region (p = 0.008) volumes, and reduced episodic memory (p = 0.046) 24 years later.	29093073
Inflammation, Nerve Degeneration	Altered Intercellular Communication	Our prospective findings provide evidence for what may be an early contributory role of systemic inflammation in neurodegeneration and cognitive aging.	29093073
Inflammation, Liver damage	Altered Intercellular Communication	These findings suggest that reduced NFKBIA function leads to activation of the NF-kB pathway, and consequently causes inflammation and liver damage among patients with chronic HBV infection.	29093318
Granulomatous inflammation	Altered Intercellular Communication	Transbronchial lung biopsy revealed the presence of granulomatous inflammation.	29093420
Inflammation, Postoperative Period	Altered Intercellular Communication	A surgical approach was not indicated because a few days may have already passed since postoperative perforation occurred and the spread of inflammation to the retroperitoneum was suspected.	29094323
Inflammatory abnormality of the eye	Altered Intercellular Communication	To investigate a pixel densitometry index (PDI) for measuring ocular surface inflammation (OSI).	29095066
Inflammation	Altered Intercellular Communication	Autoantibody deposition in the skin causes inflammation and intraepidermal akantholysis.	29096849
Inflammation	Altered Intercellular Communication	Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial.	29097438
Inflammation	Altered Intercellular Communication	Compared with refined grain diet, whole grain diet did not alter insulin sensitivity and gut microbiome but reduced body weight and systemic low-grade inflammation.	29097438
Kidney Failure, Chronic, Inflammation, Atherosclerosis	Altered Intercellular Communication	Chronic inflammation may contribute to atherosclerosis and cardiovascular (CVD) mortality in end-stage kidney disease (ESKD).	29097485
palladium, HD Term Type, Inflammation	Altered Intercellular Communication	To examine the effects of initiating HD and PD upon inflammation and CVD risk markers in ESKD patients.	29097485
Inflammation, Manufactured sign	Altered Intercellular Communication	Of the 53 resected appendixes, the histopathological evaluation showed 33 (62.2%) inconspicuous appendices, 11 (20.8%) post-inflammatory changes, 4 (7.5%) with chronical signs of inflammation and 3 (5.7%) with signs of acute inflammation.	29098385
Inflammation, Metabolic Diseases	Altered Intercellular Communication	A multifunctional diet (MFD) targeting subclinical inflammation was developed as a tool to decrease risk factors for cardiometabolic disease in healthy "at-risk" individuals (BMI 25-33 kg/m2).	29098426
Inflammation, Atherosclerosis	Altered Intercellular Communication	Inflammation plays a key role in the development of insulin resistance and atherosclerosis.	29098425
Inflammation	Altered Intercellular Communication	Our findings indicated that a single SFA-enriched meal is able to acutely induce the IL-1b expression and regularly consumed could trigger systemic inflammation, while increased unSFA consumption could attenuate the inflammatory status.	29098425
Inflammation, Neoplasms	Altered Intercellular Communication	The correlation of C-reactive protein decrease with significantly improved OS underlines the close link between inflammation and tumor control.	29098441
Inflammation	Altered Intercellular Communication	Bacterial load (total bacterial abundance) determined local parameters of ulcer inflammation.	29098740
Communicable Diseases, Inflammation, Systemic disease, Neoplasms	Altered Intercellular Communication	IgG4-RD could mimic conditions other than tumors, such as infection, inflammation, or other systemic disorders.	29099539
Inflammation, ETV3 wt Allele	Altered Intercellular Communication	Both MetS components and biomarkers of inflammation (IF) are predictive factors for LVDD.	29099655
Communicable Diseases, Inflammation, Tuberculosis, Pulmonary	Altered Intercellular Communication	Serum samples from 319 protocol-correct, culture-confirmed pulmonary tuberculosis patients treated under direct observation as part of an international, phase 2 trial were screened for 70 markers of infection, inflammation, and metabolism.	29100778
Atherosclerosis	Altered Intercellular Communication	Midlife Systemic Inflammation, Late-Life White Matter Integrity, and Cerebral Small Vessel Disease: The Atherosclerosis Risk in Communities Study.	29101255
Inflammation, Leukoaraiosis, One Vessel Coronary Disease	Altered Intercellular Communication	It is currently unclear whether midlife systemic inflammation promotes the development of white matter (WM) abnormalities and small vessel disease in the elderly.	29101255
Inflammation	Altered Intercellular Communication	Our findings support the hypothesis that midlife systemic inflammation may promote the development of chronic microangiopathic structural WM abnormalities in the elderly.	29101255
Airway structure, ARCN1 gene	Altered Intercellular Communication	A nested subcohort of 141 patients, followed for up to 6 months, was studied to test if MBL deficiency was associated with altered sputum microbiota, through 16S rRNA PCR and sequencing, or airway inflammation during stable and exacerbated COPD.	29101284
Airway structure	Altered Intercellular Communication	There were lower levels of airway inflammation in patients with MBL deficiency.	29101284
Human Placental Lactogen, muscle mass	Altered Intercellular Communication	Inflammation markers were associated with measures of muscle mass, strength and function in HCS.	29101476
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Red blood cell distribution width: a potential laboratory parameter for monitoring inflammation in rheumatoid arthritis.	29101675
Refractory anemias, Tumor necrosis, Rheumatoid Arthritis, Inflammation	Altered Intercellular Communication	Correlation analysis of red blood cell distribution width (RDW) and C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), tumor necrosis factor a (TNF-a), interleukin (IL)-6, and IL-10 in rheumatoid arthritis (RA) to investigate whether RDW can serve as a potential parameter for indicating inflammation in RA patients.	29101675
Refractory anemias, Inflammation	Altered Intercellular Communication	RDW was increased in patients with RA which was associated with inflammation in RA, suggesting that RDW may be a potential auxiliary marker for indicating inflammation process in RA conveniently.	29101675
Inflammation, Calcinosis	Altered Intercellular Communication	Symptomatic lesions exhibited less calcification, with greater inflammation characterized by increased expression of CD68+ and CD163+ macrophage subsets, and Lp-PLA2.	29101839
Cessation of life, Inflammation, Atherosclerotic lesion, Necrosis	Altered Intercellular Communication	Statin treatment has no effect on local atherosclerotic lesion Lp-PLA2 activity, therefore, the addition of anti-inflammatory treatments to further decrease macrophage Lp-PLA2 expression in atherosclerotic lesions may reduce lesional inflammation and cell death, and prevent necrotic core expansion and lesion progression.	29101839
Pneumonitis	Altered Intercellular Communication	r-Der f 31 can induce allergic pulmonary inflammation in the mouse model.	29102047
Inflammation, Malnutrition	Altered Intercellular Communication	Low T3 and FT3 levels are correlated with malnutrition and inflammation parameters.	29102271
Amblyopia, Vitreous inflammatory cells	Altered Intercellular Communication	Vitreous inflammation gradually resolved with oral steroids, and amblyopia treatment with left eye patching was advised.	29102673
Crohn Disease, Inflammatory abnormality of the eye, Uveitis	Altered Intercellular Communication	This case of Crohn's disease and uveitis is unusual in that ocular inflammation preceded intestinal involvement, with the atypical feature of chronic intermediate uveitis.	29102673
Inflammation, Pulmonary Edema	Altered Intercellular Communication	Negative pressure ventilation decreases inflammation and lung edema during normothermic ex-vivo lung perfusion.	29103845
Inflammation, Lung Injury	Altered Intercellular Communication	Utilization of an NPV strategy during extended EVLP is associated with significantly less inflammation, and lung injury, irrespective of perfusate solution composition.	29103845
Communicable Diseases, Inflammation	Altered Intercellular Communication	The presence of human papilloma virus (HPV) infection and the occurrence of genital inflammation were documented.	29104417
Human papilloma virus infection, Inflammation, Vulval intraepithelial neoplasia	Altered Intercellular Communication	Smoking, HPV infection, genital inflammation, and complete pubic hair removal were significantly more common in the vulvar dysplasia/cancer group.	29104417
Inflammation, Vulval intraepithelial neoplasia, Malignant Neoplasms	Altered Intercellular Communication	Our findings suggest that partial or complete pubic hair shaving using a razor is correlated with and could be a potential risk factor for the development of genital inflammation, vulvar dysplasia, and malignancies.	29104417
Deficit	Altered Intercellular Communication	We hypothesized that these hormonal deficits lead to increased apoptosis of the epithelial cells and plasmacytoid dendritic cell (pDC)-mediated proinflammatory host responses.	29105068
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Acute effect of a resistance exercise session on markers of cartilage breakdown and inflammation in women with rheumatoid arthritis.	29105312
Refractory anemias, Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	To assess the acute effect of resistance exercise (RE) on circulating biomarkers of cartilage breakdown and inflammation in women with rheumatoid arthritis (RA).	29105312
Refractory anemias, Inflammation	Altered Intercellular Communication	Women with and without RA have similar changes in response to a RE session in levels of inflammation biomarkers, but not of cartilage breakdown.	29105312
Inflammation, physiopathological, Impaired	Altered Intercellular Communication	Angiotensin converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs) were inversely associated with cardiac impairment, inflammation, and renal tubular damage, but not with glomerular dysfunction.	29105751
Pain Distress Question, Inflammation, Anxiety, CTCAE 3.0, Chronic pain	Altered Intercellular Communication	In the multivariate models, moderate to severe average pain in the 4 weeks after ICUDC , lower age, female sex, increased inflammation and chronic pain conditions and increased levels of anxiety before ICU admission were predictive for CIRP.	29105897
Portal Hypertension, Inflammation, CRNKL1 wt Allele	Altered Intercellular Communication	Circulating CXCL10 in cirrhotic portal hypertension might reflect systemic inflammation and predict ACLF and mortality.	29105936
Inflammation, Fibrosis Assessment, Injury of liver	Altered Intercellular Communication	CXCR% ligands play an important role in hepatic injury, inflammation and fibrosis.	29105936
Decompensation, Inflammation, Hypertension, CTCAE, CRNKL1 wt Allele	Altered Intercellular Communication	Circulating CXCL10 possibly reflects systemic inflammation and it is correlated with acute decompensation, ACLF and complications in patients with severe portal hypertension receiving TIPS.	29105936
Inflammation, SDSL gene	Altered Intercellular Communication	However, the association between the biomarkers of inflammation and angiogenesis, and the clinical and radiological characteristics of CSDH patients, need further investigation.	29107999
Inflammation, Bipolar Disorder	Altered Intercellular Communication	Recent evidence suggests a notable role for inflammation and immune dysregulation in the neuroprogression of bipolar disorders (BD).	29108425
Inflammation, Pathological Dilatation	Altered Intercellular Communication	Vascular pathology was mapped, and correlations were sought between the vascular findings and bowel distension, inflammation, neuromuscular anatomy, preoperative clinical variables, and postsurgical complications.	29108502
Inflammation, Necrosis	Altered Intercellular Communication	Adventitial inflammation and/or medial necrosis was present in the immature form (6/16).	29108502
Cryptitis, Acute inflammation	Altered Intercellular Communication	Confocal imaging focused on 2 highly reproducible histologic hallmarks of active colonic inflammation: focal cryptitis and crypt architectural abnormality.	29108979
Organ Dysfunction Scores, Malignant Neoplasms	Altered Intercellular Communication	We defined young adult cancers as those occurring between the ages of 20 and 39 years because these individuals will have passed puberty and adolescence, but not yet experienced the effects of hormonal decline, immune response deterioration, or organ dysfunction associated with chronic health conditions.	29111259
Inflammation	Altered Intercellular Communication	C-reactive protein concentration as a prognostic factor for inflammation in the management of odontogenic infections.	29113735
Inflammation, Hypertension, CTCAE	Altered Intercellular Communication	In particular, significant variants were mapped to genes known to be associated with inflammation, hypertension, lipid metabolism, height, and increased lifespan in mice.	29113935
Inflammation, Kidney Diseases	Altered Intercellular Communication	All 3 markers showed moderate correlations with markers of kidney and liver disease and inflammation (ie, systemic symptoms of RVCL-S).	29114091
Nonalcoholic Steatohepatitis, Hypogonadism, hormone deficiency	Altered Intercellular Communication	This case indicates that a long-standing growth hormone deficiency and hypogonadism may lead to LC as a type of burn-out non-alcoholic steatohepatitis.	29115108
Inflammation, Dissection of aorta, Data types - Address	Altered Intercellular Communication	Aortic dissection (AD) results from the imbalance between synthesis and degradation of extracellular matrices in aortic wall, which is characterized by chronic inflammation.	29115411
Inflammation, Dental caries	Altered Intercellular Communication	Dental examinations were performed to assess the presence of gingival inflammation, dental caries prevalence (DMFT>=1) and dental caries experience (mean DMFT).	29116296
Inflammation	Altered Intercellular Communication	Histologic evaluation indicated the presence of fibrotic changes, associated with granulation tissue and rare cellular elements, compatible with chronic inflammation.	29117664
Inflammation, Disorder of Achilles tendon, Rupture	Altered Intercellular Communication	Chronic inflammation is a feature of Achilles tendinopathy and rupture.	29118051
Inflammation, Disease	Altered Intercellular Communication	Recent investigation of human tissue and cells from positional tendons such as the rotator cuff has clarified the importance of inflammation in the development and progression of tendon disease.	29118051
Inflammation, Disorder of Achilles tendon, Rupture	Altered Intercellular Communication	Using tissue biopsies from patients, we investigated if inflammation is a feature of Achilles tendinopathy and rupture.	29118051
Inflammation	Altered Intercellular Communication	Tissue and cells derived from tendinopathic and ruptured Achilles tendons show evidence of chronic (non-resolving) inflammation.	29118051
Inflammation	Altered Intercellular Communication	Differences seen in the profile of ruptured Achilles are likely to be attributable to a superimposed phase of acute inflammation and neo-vascularisation.	29118051
Inflammation	Altered Intercellular Communication	Strategies that target chronic inflammation are of potential therapeutic benefit for patients with Achilles tendon disease.	29118051
Inflammation, Infantile Colic, Crying	Altered Intercellular Communication	Impact of Lactobacillus reuteri colonization on gut microbiota, inflammation, and crying time in infant colic.	29118383
Colonization, Gastrointestinal inflammation	Altered Intercellular Communication	There were no differences in E. coli colonization rates or densities, microbial diversity or intestinal inflammation by L. reuteri colonization status.	29118383
Asthmatic Airway Remodeling	Altered Intercellular Communication	Exposure-response relationships are inconsistent in subjects with suspected asthmatic airway inflammation (FeNO >=50 ppb).	29118577
ARCN1 gene, Asthmatic Airway Remodeling, Asthma, Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome	Altered Intercellular Communication	More careful risk assessment is needed in occupational inhalation exposure, since COPD with asthmatic airway inflammation, or asthma-COPD overlapping syndrome, may have the distinguishing features of both COPD and asthma.	29118577
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	Balance of Fatty Acids and Their Correlations with Parameters of Lipid Metabolism and Markers of Inflammation in Men with Coronary Atherosclerosis.	29119389
Inflammation, Coronary Arteriosclerosis	Altered Intercellular Communication	We studied the balance of fatty acids and their correlation with parameters of lipid metabolism and inflammation markers in men with coronary atherosclerosis.	29119389
Inflammation, Atherosclerosis	Altered Intercellular Communication	Lipid metabolism disturbances in coronary atherosclerosis were accompanied by changes in not only lipid spectrum and inflammation markers, but also fatty acids balance.	29119389
Inflammation, Metabolic Syndrome X, Diabetes Mellitus, Obesity, Osteopenia	Altered Intercellular Communication	Bone Mineral Density in Relation to Metabolic Syndrome Components in Postmenopausal Women With Diabetes Mellitus Type 2 Diabetes mellitus type 2 is associated with greater bone mineral density (BMD) due to obesity, although rapid bone loss observed over time could be explained by elevated chronic inflammation.	29120134
Presenile dementia, Inflammation, Data types - Address	Altered Intercellular Communication	We confirm established associations between AD pathology and dementia, albeit with increased, presumably aging-related variability, and identify sets of co-expressed genes correlated with pathological tau and inflammation markers.	29120328
Inflammation, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	KEGG pathway and gene ontology (GO) analysis revealed that those differentially expressed genes related to inflammation, lipid metabolism and myocardial processes were particularly noted in the CHD group, but not in non-CHD.	29121163
Inflammation, Coronary Arteriosclerosis, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Particularly, those genes related to inflammation, lipid metabolism and myocardial processes are differentially expressed in PVAT-CA and PVAT-ITA in CHD patients, suggesting an important role of PVAT in the development of coronary atherosclerosis.	29121163
Crohn Disease, Malignant Head and Neck Neoplasm	Altered Intercellular Communication	Managing head and neck malignancy arising in a field of Crohn disease inflammation: Report of a case.	29121377
Malaria, Anemia	Altered Intercellular Communication	Malaria exacerbates inflammation-associated elevation in ferritin and soluble transferrin receptor with only modest effects on iron deficiency and iron deficiency anaemia among rural Zambian children.	29121448
Inflammation, Malaria	Altered Intercellular Communication	We estimated the unadjusted ID or IDA prevalence, and then adjusted for inflammation alone (IDI or IDAI ) or inflammation and malaria (IDIM or IDAIM ).	29121448
Inflammation, muscle mass	Altered Intercellular Communication	The aging process is associated with several changes in the elderly such as the decrease in cardiorespiratory fitness, strength and muscle mass, in addition to chronic low-grade inflammation.	29121681
Inflammation	Altered Intercellular Communication	Detection of Aa from preadolescent African American children was associated with signs of periodontal inflammation.	29122069
Diabetic Nephropathy, Inflammation	Altered Intercellular Communication	Association of TNFR1 with markers of systemic inflammation and adipose stress indicates that TNFR1 may be a biomarker of these processes as components of the pathogenesis of diabetic kidney disease.	29122448
Inflammation, Trauma, Nervous System, Hyperglycemia, Hypoxia, Diabetes Mellitus	Altered Intercellular Communication	Proposed mechanisms of neuronal damage caused by diabetes that are downstream of hyperglycemia and/or loss of insulin signaling include ischemic hypoxia, inflammation and loss of neurotrophic support.	29122628
Inflammation, Liver carcinoma	Altered Intercellular Communication	Irrespective of the underlying aetiology, 90% of hepatocellular carcinomas arise and progress on a background of chronic inflammation.	29123264
Malignant neoplasm of liver, TNM Staging System, Neoplasm Metastasis, Neoplasms	Altered Intercellular Communication	In both UK and Hong Kong cohorts, neutrophils, platelets, lymphocytes, the neutrophil/lymphocyte ratio (NLR) and the Systemic Immune-Inflammation Index (SII) correlated stepwise, either increasing or decreasing (lymphocytes), with tumour node metastasis (TNM) and Childs-Pugh stage, PST and consequently with the combined Barcelona Clinic for Liver Cancer stage.	29123264
Gingivitis, Metabolic Syndrome X	Altered Intercellular Communication	Association between metabolic syndrome and gingival inflammation in obese children.	29124887
Granulomatous inflammation, Primary malignant neoplasm, Malignant Neoplasms	Altered Intercellular Communication	Specifically, TB provided clear histological diagnosis of malignancy (either primary lung cancer or metastases from extra-thoracic cancer) in 30/46 (65.2%) patients and granulomatous inflammation in 11/46 (23.9%) of patients.	29124891
Fibrous, Fatty degeneration, Inflammation, Nodularity	Altered Intercellular Communication	Histological features such as nodularity, fibrous bands, ductular proliferation, steatosis, ballooned hepatocytes and lymphocytic inflammation were also scored.	29127141
Inflammation, Fatty degeneration, Fibrous	Altered Intercellular Communication	Copper deposition in IHA was significantly associated with presence of lymphocytic inflammation (P=0.04) but not associated with features like nodularity, fibrous bands, ductular proliferation, ballooned hepatocytes and steatosis (P>0.05, for all).	29127141
Inflammation	Altered Intercellular Communication	Increased chronic inflammation is believed to play a key role in the development of CRCI related to chemotherapy but studies assessing this hypothesis specifically in patients receiving chemotherapy are rare.	29128118
Inflammation, Nasopharyngeal carcinoma, Neoplasms	Altered Intercellular Communication	Based on current concepts in tumour related inflammation the inflammatory marker, neutrophil-lymphocyte ratio was tested to find its relationship with prognosis in nasopharyngeal carcinoma.	29128472
Osteoarthritis, Knee, Inflammation, Pain Distress Question	Altered Intercellular Communication	Monocyte activation is elevated in women with knee-osteoarthritis and associated with inflammation, BMI and pain.	29128509
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Low-grade inflammation occurs in OA and correlates with disease severity and progression.	29128509
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Since monocyte development and function is altered by systemic inflammation, we analyzed monocyte numbers and function between individuals with knee OA and healthy age- and sex-matched controls.	29128509
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	We analyzed markers of soluble and cellular inflammation in peripheral blood of women with knee OA and compared them to healthy age- and sex-matched controls.	29128509
Inflammation	Altered Intercellular Communication	Modulating systemic inflammation and monocyte recruitment to the synovium could be of therapeutic benefit.	29128509
Neurocognitive Disorders, Inflammation, Hand	Altered Intercellular Communication	HIV-1-associated neurocognitive disorders (HAND) is associated with blood-brain-barrier (BBB) inflammation, and inflammation involves toll-like receptors (TLRs) signaling.	29128906
Inflammation, Acquired Immunodeficiency Syndrome, physiopathological, Hand	Altered Intercellular Communication	These data suggest that viral immune recognition via endothelial TLR3 is involved in endothelial inflammation and BBB dysfunction in HIV/AIDS and HAND.	29128906
Refractory anemias, Inflammation	Altered Intercellular Communication	5-HETE, 15-HETE, 9-HODE, and 13-HODE levels were significantly increased in HDL and LDL from patients with active RA (n = 10) compared to healthy controls (n = 8) and correlated significantly with measures of systemic inflammation, particularly in HDL (r = 0.65-0.80, p values < 0.004).	29129008
Inflammation, Atherosclerosis	Altered Intercellular Communication	Aging is an important determinant of the rate of atherosclerosis development, mainly through low-grade inflammation.	29129737
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Galectin-3 plays an important role in modulating cardiac inflammation and fibrosis.	29129812
Inflammation, Urticaria, Chronic Spontaneous Urticaria	Altered Intercellular Communication	Elevated levels of C-reactive protein (CRP), a sensitive marker of inflammation, have been consistently reported in chronic spontaneous urticaria (CSU).	29130488
Inflammation, Cachexia, Chronic Kidney Diseases	Altered Intercellular Communication	Protein energy wasting (PEW) is a common syndrome in patients with chronic kidney disease, related to changes in hydration status, decreased food intake and inflammation.	29130711
Inflammation, Leukocytosis, Neutrophilia (finding)	Altered Intercellular Communication	Here, markers for inflammation such as CRP, leukocytosis, and neutrophilia were elevated in 50-73% of the PG patients.	29130957
Inflammation, Malnutrition	Altered Intercellular Communication	These are associated with malnutrition and inflammation, and hence, may provide benefit in predicting mortality among hemodialysis patients.	29130984
Periodontitis, Psoriasis	Altered Intercellular Communication	Periodontitis and psoriasis are suggested to be co-occurring, chronic inflammatory conditions with overlapping characteristics.	29131099
Inflammation, Kit Ligand, human, Endothelial dysfunction	Altered Intercellular Communication	Nesfatin-1 could play a role in the pathogenesis of SCF phenomenon with mechanisms such as inflammation and endothelial dysfunction.	29131290
Inflammation, Disease	Altered Intercellular Communication	Inflammation plays an important role in the pathophysiology of many diseases and could cause damage by means of oxidative stress.	29131698
Inflammation	Altered Intercellular Communication	Pulmonary and hepatic 18F-fluoro-deoxy-D-glucose (18F-FDG) uptake was calculated to determine the status of inflammation by 18F-fluoro-deoxy-D-glucose-positron emission tomography (18FDG-PET) scan.	29131698
vascular inflammations	Altered Intercellular Communication	Internal tissue references for 18Fluorodeoxyglucose vascular inflammation imaging: Implications for cardiovascular risk stratification and clinical trials.	29131857
Inflammation	Altered Intercellular Communication	However, variation in blood activity may mask artery wall signal reflective of inflammation, which requires normalization.	29131857
Inflammation	Altered Intercellular Communication	Increased Th1/Th17 Responses Contribute to Low-Grade Inflammation in Age-Related Macular Degeneration.	29132135
Preterm premature rupture of membranes (disorder)	Altered Intercellular Communication	Infection induced-inflammation and other risk factors for spontaneous preterm birth (PTB) and preterm premature rupture of membranes (pPROM) may cause a redox imbalance, increasing the release of free radicals and consuming antioxidant defenses.	29132320
Malignant neoplasm of endometrium, Endometritis	Altered Intercellular Communication	The major risk factors for endometrial cancer are related to the exposure of endometrium to estrogens not opposed to progestogens, that can lead to a chronic endometrial inflammation.	29132343
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Diet may play a role in cancer risk by modulating chronic inflammation.	29132343
Inflammation	Altered Intercellular Communication	The neutrophil-lymphocyte ratio (NLR) is a recognized marker of inflammation associated with poor outcomes in various clinical situations.	29132702
Chronic Kidney Diseases, Renal tubular disorder, Endothelial dysfunction, Nephritis	Altered Intercellular Communication	Serum uric acid concentrations increase in chronic kidney disease (CKD) and may lead to tubular injury, endothelial dysfunction, oxidative stress, and intrarenal inflammation.	29132945
Airway structure, Asthma	Altered Intercellular Communication	In addition, more activity and less sedentary time would be associated with better clinical outcomes and markers of systemic and airway inflammation in people with severe asthma.	29133222
Inflammation, Asthma	Altered Intercellular Communication	Adults with severe asthma (n = 61) and sex- and age-matched controls (n = 61) underwent measurement of lung function, exercise capacity, asthma control, health status, and airway and systemic inflammation.	29133222
Inflammation, Asthma	Altered Intercellular Communication	Higher levels of activity and lower levels of sedentary time are associated with better exercise capacity, asthma control, and lower levels of systemic inflammation.	29133222
HD Term Type, Inflammation, Muscle damage	Altered Intercellular Communication	Moreover, moderate intensity intradialytic exercise did not exacerbate the systemic inflammation or induce muscle damage during HD therapy.	29134614
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Zonulin, inflammation and iron status in patients with early stages of chronic kidney disease.	29134616
Inflammation	Altered Intercellular Communication	There were no statistically significant differences in zonulin concentration between patients with and without inflammation.	29134616
Inflammation, hepcidin	Altered Intercellular Communication	Zonulin was significantly correlated with hepcidin only in patients with inflammation.	29134616
Cerebral Amyloid Angiopathy, Inflammation	Altered Intercellular Communication	Cerebral amyloid angiopathy associated with inflammation: A systematic review of clinical and imaging features and outcome.	29134927
Cerebral Amyloid Angiopathy, Inflammation, Deposition	Altered Intercellular Communication	Background Cerebral amyloid angiopathy associated with inflammation is an increasingly recognized condition, characterized by an inflammatory response to the vascular deposits of b-amyloid within the brain that are the hallmark of cerebral amyloid angiopathy.	29134927
Vasculitis, Inflammation, Vasculitis, CTCAE	Altered Intercellular Communication	Two main patterns of this inflammatory response have been identified to date: one involving a perivascular inflammatory cell infiltrate (cerebral amyloid angiopathy-related inflammation); the other a transmural vasculitic process (A-beta related angiitis).	29134927
Cerebral Amyloid Angiopathy, Inflammation, Cerebral Hemorrhage	Altered Intercellular Communication	Unlike cerebral amyloid angiopathy itself, which predisposes to intracerebral hemorrhage and has no known treatment, cerebral amyloid angiopathy associated with inflammation typically presents in diverse ways and diagnosis may be challenging and delayed.	29134927
Vasculitis	Altered Intercellular Communication	Summary of review We identified 213 distinct pathologically proven cases of cerebral amyloid angiopathy-related inflammation/A-beta related angiitis, from 104 publications.	29134927
Cerebral Amyloid Angiopathy, Inflammation	Altered Intercellular Communication	The clinical presentation, imaging features, pathology, treatment, and outcomes of cerebral amyloid angiopathy associated with inflammation are described.	29134927
Vascular Diseases, Inflammation, Impaired cognition, Seizures, Headache	Altered Intercellular Communication	Conclusions Cerebral amyloid angiopathy associated with inflammation is an important and increasingly recognized clinical condition, which affects the older patient population and presents most commonly with cognitive decline, seizures, and headaches.	29134927
Inflammation, Heart valve disease, Conductive hearing loss	Altered Intercellular Communication	He was diagnosed to have inflammation of the tracheobronchial cartilage, cardiac valvulopathy and conductive hearing loss after intensive diagnostic studies.	29135403
Inflammation	Altered Intercellular Communication	Chronic low grade inflammation is a fundamental mechanism of aging.	29135455
Fibrosis Assessment, FAM126A gene	Altered Intercellular Communication	NLR and AAR, when combined to produce an inflammation-based index and fibrosis score, is an independent marker of poor prognosis in patients with HCC receiving TACE.	29137051
Inflammation	Altered Intercellular Communication	A subsequent brain biopsy showed necrotizing granulomatous inflammation suggestive of NS.	29137054
Airway structure, Asthma	Altered Intercellular Communication	Virus-triggered exacerbation in allergic asthmatic children: neutrophilic airway inflammation and alteration of virus sensors characterize a subgroup of patients.	29137638
Airway structure, Infected	Altered Intercellular Communication	Airway inflammation in infected patients was characterized by significantly higher IL-5 concentration and eosinophil count.	29137638
Airway structure	Altered Intercellular Communication	This subgroup is characterized by altered PRR function and a different pattern of airway inflammation.	29137638
Inflammation, HIV-1 Infection Pathway, HIV Enteropathy, Endothelial dysfunction, Cerebrovascular Disorders	Altered Intercellular Communication	Recently "HIV-associated vasculopathy" has been used to describe the cerebrovascular disorder related to HIV-1 infection that is caused by the endothelial dysfunction induced from chronic inflammation and cytokine imbalances due to HIV-1 infection.	29138020
ARCN1 gene, Inflammation, Pulmonary Emphysema, Bronchiectasis	Altered Intercellular Communication	Inflammation and chronic colonization of Haemophilus influenzae in sputum in COPD patients related to the degree of emphysema and bronchiectasis in high-resolution computed tomography.	29138549
ARCN1 gene, Inflammation, Exacerbation, Airway structure	Altered Intercellular Communication	The presence of bacteria in the lower airways in COPD results in inflammation, further airway structural damage, and might lead to repeated exacerbations.	29138549
Inflammation, Colonization, Pulmonary Emphysema, Bronchiectasis	Altered Intercellular Communication	We have previously shown that chronic colonization of Haemophilus influenzae during stable disease is related to increased inflammation, and we now aimed to relate previous findings of bacterial colonization and inflammation to the degree of radiological findings of bronchiectasis and emphysema.	29138549
Inflammation, Pulmonary Emphysema, Bronchiectasis	Altered Intercellular Communication	During exacerbation, there was no longer any correlation between emphysema degree and inflammation, but patients with bronchiectasis showed higher sputum purulence score than patients without bronchiectasis.	29138549
Inflammation, Colonization, Pulmonary Emphysema, Bronchiectasis	Altered Intercellular Communication	The presence of emphysema is more related to inflammation, while bronchiectasis is associated with bacterial colonization.	29138549
ARCN1 gene, Inflammation	Altered Intercellular Communication	Longevity gene, SIRT1, is reported to be involved in the pathogenesis of COPD by regulating the signaling pathways of oxidative stress, inflammation, and aging.	29138552
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Inflammation, apoptosis, and oxidative stress levels were severe in the CSE-treated emphysema mice compared with the control group, which was inhibited by the overexpression of PRMT6.	29138553
Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	The overexpression of PRMT6 might inhibit inflammation, apoptosis, and oxidative stress in CSE-induced emphysema mediated by H3R2me2a.	29138553
Inflammation, Unspecified visual loss	Altered Intercellular Communication	These results provide a comprehensive framework for the role of Ab42 in visual loss due to inflammation present with aging and offer some clues for fruitful avenues for the study of healthy aging.	29138750
Sepsis, Inflammation	Altered Intercellular Communication	Taken together, the results suggested that Lp-PLA2, with respect to other markers of inflammation, may have a role as a prognostic marker in sepsis, and provide background evidence for further trials to evaluate the clinical and pathophysiologic roles of Lp-PLA2 in sepsis.	29138849
Inflammation, Tooth Loss, Cardiovascular Diseases	Altered Intercellular Communication	Associations among tooth loss, systemic inflammation and antibody titers to periodontal pathogens in Japanese patients with cardiovascular disease.	29139559
Inflammation	Altered Intercellular Communication	Inhibition of neurogenesis in our patient, which cannot be explained by the fulminant nature of his symptoms, may be related to inflammation and immune response.	29141824
Inflammation, Infection, Colorectal Carcinoma	Altered Intercellular Communication	Worse Preoperative Status Based on Inflammation and Host Immunity Is a Risk Factor for Surgical Site Infections in Colorectal Cancer Surgery.	29142183
Primary malignant neoplasm, Malnutrition, Cachexia	Altered Intercellular Communication	The modified Glasgow Prognostic Score (mGPS) is an inflammation-based measure of malnutrition that reflects a state of cachexia in cancer patients.	29142183
Kidney Failure, Chronic, Inflammation	Altered Intercellular Communication	Complications of end-stage renal disease (ESRD) are critically related to inflammation.	29142271
Kidney Failure, Chronic, Inflammation, palladium, HD Term Type	Altered Intercellular Communication	We therefore studied faecal microbiome composition and function as well as inflammation and gut permeability in 30 patients with ESRD (15 HD, 15 PD) and compared to 21 healthy controls.	29142271
palladium, HD Term Type, Gastrointestinal inflammation	Altered Intercellular Communication	In HD but not in PD, changes in microbiome composition were associated with an increase in c-reactive protein (CRP) but not with intestinal inflammation or gut permeability.	29142271
Inflammation	Altered Intercellular Communication	These differences are associated with systemic inflammation and cannot completely be explained by dialysis vintage.	29142271
Inflammation, Vascular System Injuries	Altered Intercellular Communication	Inflammation mediated through the IL-8 pathway predicted microvascular injury while Flt-1, a potential marker of angiogenesis and endothelial repair, might have a significant protective role.	29145197
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Degree of inflammation and interstitial fibrosis in the cortex of transplanted kidneys were estimated semi-quantitatively.	29146138
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Markers of inflammation, including plasma C-reactive protein (CRP), are associated with an increased risk of cardiovascular disease, and it has been suggested that this association is causal.	29146277
Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases	Altered Intercellular Communication	However, the relationship between inflammation and cardiovascular disease has not been extensively studied in patients with chronic kidney disease.	29146277
ARCN1 gene, Inflammation	Altered Intercellular Communication	Clinical trials targeting eosinophilic inflammation in COPD should consider assessing sputum eosinophils.	29146301
Airway structure	Altered Intercellular Communication	Microbial diversity and relative abundance of Streptococcus, Prevotella and Veillonella were inversely associated with airway inflammation.	29146601
Inflammation	Altered Intercellular Communication	Increased Levels of sRAGE in Diabetic CKD-G5D Patients: A Potential Protective Mechanism against AGE-Related Upregulation of Fibroblast Growth Factor 23 and Inflammation.	29147074
Inflammation, Cardiac complication	Altered Intercellular Communication	Indeed, its increase could be a potential protective mechanism against the increased risk of cardiovascular complications related to AGEs and inflammation.	29147074
Memory Disorders	Altered Intercellular Communication	The changing hormonal milieu during the menopausal transition may contribute to the development of memory disorders.	29147956
Refractory anemias, Inflammation	Altered Intercellular Communication	These results indicate that the mRNA expression of PADI2, PADI4 and Sp1 is upregulated in RA BM CD34+ cells independently of the systemic inflammation or treatment regimen.	29148420
Inflammation, Hepatobiliary Disorder, Prostatic Diseases, Ulcerative Colitis	Altered Intercellular Communication	Studies discussing inflammation and oxidative stress state that these conditions are known contributors in the pathogenesis of cholestatic diseases and ulcerative colitis, and studies examining patients with liver disease have found decreased antioxidant status and significant elevation of lipid peroxides as compared with healthy subjects.	29148959
Inflammation, Leucocytic infiltrate, Congenital Abnormality	Altered Intercellular Communication	Histological analysis of the placenta showed moderate inflammatory infiltration; however, whether fetal malformation in NMOSD is related to inflammation and AQP4-IgG remains to be determined.	29149698
Inflammation, Asthma	Altered Intercellular Communication	Sensitization to Staphylococcus aureus enterotoxins (SEs) augments eosinophilic inflammation in asthma.	29150068
Inflammation, Asthma	Altered Intercellular Communication	To clarify the role of SEs on clinical indexes, including eosinophilic inflammation and lung function in smokers with asthma.	29150068
Inflammation, Asthma, Chronic Obstructive Airway Disease	Altered Intercellular Communication	In current or ex-smokers with asthma, the association of sensitization to SEs with eosinophilic inflammation, airflow limitation, or treatment steps was determined.	29150068
Inflammation, Asthma	Altered Intercellular Communication	Sensitization to SEs is increased in smokers with asthma, and it may be a marker of eosinophilic inflammation and severe asthma in smokers with asthma.	29150068
allergic inflammation	Altered Intercellular Communication	The tryptophan metabolic pathway mediated by indolamine 2,3-dioxygenase (IDO), a tryptophan-degrading enzyme, plays an important role in controlling the development of allergic inflammation.	29150070
Allergic	Altered Intercellular Communication	The fractional concentration of exhaled nitric oxide (FeNO) is closely associated with the allergic state and is extensively used for the clinical evaluation of airway allergic inflammation.	29150070
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Three linking pathways were revealed: sedentariness, inflammation and metabolic syndrome.	29150168
Inflammation, Bacterial Infections	Altered Intercellular Communication	When it feeds on the blood through the scalp of its host, the anticoagulant in its saliva causes scalp inflammation and itching, and consequent scratching by the host causes further inflammation from bacterial infection.	29150362
Acute Lung Injury, Non-Small Cell Lung Carcinoma, Pneumonitis	Altered Intercellular Communication	Pretreatment advanced lung cancer inflammation index (ALI) for predicting early progression in nivolumab-treated patients with advanced non-small cell lung cancer.	29150906
Acute Lung Injury, Non-Small Cell Lung Carcinoma, Pneumonitis	Altered Intercellular Communication	Because the baseline advanced lung cancer inflammation index (ALI) is reportedly associated with patient outcomes, we investigated whether the pretreatment ALI is prognostic in NSCLC patients treated with nivolumab.	29150906
HD Term Type, Inflammation	Altered Intercellular Communication	Thus, uremic toxins may stimulate NF-kB mRNA and decrease Nrf2 expression in HD patients and, consequently, trigger inflammation and oxidative stress.	29151180
Inflammation, Thrombosis	Altered Intercellular Communication	Objective The neutrophil-to-lymphocyte ratio (NLR) is an inflammation marker that can be used to detect atrial inflammatory changes, which may contribute to a reduced left atrial (LA) function and thrombosis.	29151509
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Furthermore, lower FC baseline values significantly correlated to the presence of mucosal healing in endoscopy (69.0 mg/g, 30.0-128.0 vs 481.0, 278.0-600.0, in those with mucosal inflammation, median with IQR, P < 0.001).	29151692
Inflammation, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic inflammation and chronic renal failure were the most frequent causes of anemia in our population, and in >35% of patients a multifactorial anemia was diagnosed.	29153343
Inflammation, Anemia	Altered Intercellular Communication	Our data confirm the high prevalence of anemia in patients hospitalized in an Internal Medicine Department, with a remarkable burden of mild forms, and of chronic inflammation's pathogenic mechanism.	29153343
Inflammation, Asthma	Altered Intercellular Communication	IL1RL1 SNPs may characterize the eosinophilic phenotype with greater eosinophilic inflammation in the Japanese asthma cohort.	29153414
Airway structure, ARCN1 gene	Altered Intercellular Communication	Eosinophilic airway inflammation characterizes a chronic obstructive pulmonary disease (COPD) phenotype that requires more study.	29153881
Cryptococcus, Choroiditis	Altered Intercellular Communication	In the second patient, ILV recurred secondary to choroid plexus inflammation caused by cryptococcal infection.	29155114
Inflammation	Altered Intercellular Communication	This was associated with increased sterile inflammation in the skin in the same subjects related to p38 mitogen-activated protein kinase-related proinflammatory cytokine production (P < .0007).	29155150
Inflammation	Altered Intercellular Communication	Excessive inflammation in the skin early after antigen challenge retards antigen-specific immunity.	29155150
Inflammation	Altered Intercellular Communication	Surfactant protein-D (SP-D) is a collectin, which plays an important role in airway protection and inflammation.	29155458
Inflammation, Colorectal Carcinoma	Altered Intercellular Communication	Chronic inflammation is a key component in the development and progression of colorectal cancer (CRC).	29155516
Inflammation	Altered Intercellular Communication	A notable hallmark of the inflammation process is the release of pro-inflammatory cytokines by infiltrating cells of the immune system.	29155516
Rheumatoid Arthritis, Atherosclerosis	Altered Intercellular Communication	Considerable evidence supports the hypothesis that risk of atherosclerosis is increased by chronic inflammatory conditions accompanying diseases such as rheumatoid arthritis and HIV, as well as general ageing, and that this risk is predicted by monocyte activation.	29155735
Inflammation, Lung Injury, Traumatic injury	Altered Intercellular Communication	In a severe trauma model, sustained changes in terms of lung injury and inflammation are determined at day 3 post-trauma.	29156155
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Quality of life is associated with chronic inflammation in depression: A cross-sectional study.	29156363
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Inflammation may play a crucial role in the pathophysiology of depression.	29156363
Inflammation, Depression, CTCAE	Altered Intercellular Communication	However, the association between chronic inflammation and health outcomes in depression remains unclear, particularly for patient-reported outcomes.	29156363
Inflammation, Depression, CTCAE	Altered Intercellular Communication	The design of this study is cross-sectional and there are no conclusions about the directionality of the association between QoL and inflammation in depression.	29156363
Inflammation, Depression, CTCAE	Altered Intercellular Communication	This paves the way for interventions to act both on inflammation and QoL in patients with depression.	29156363
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Although high levels of sitting time are adversely related to health, it is unclear whether moving from sitting to standing provides a sufficient stimulus to elicit benefits upon markers of chronic low-grade inflammation in a population at high risk of type 2 diabetes (T2DM).	29157133
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients.	29157250
Cyst, Inflammation, Dental Leakage	Altered Intercellular Communication	Retinal cysts are formed by accumulation of fluid in the retina caused by leakages from inflammation or vitreous fractures.	29157443
Inflammation, Hallopeau-Siemens Disease, Neoplasms, Tissue damage, Damage	Altered Intercellular Communication	Sporadic cSCCs show signs of UV damage, whereas RDEB cSCCs have higher mutational rates and display tissue damage, inflammation and subsequent remodeling of the dermal ECM as tumor initiating factors.	29158163
Refractory anemias, Inflammation	Altered Intercellular Communication	Bioinformatics analysis confirmed that CASP5 was related to the development of inflammation, which is the main feature of RA.	29158166
Refractory anemias, Inflammation	Altered Intercellular Communication	In conclusion, CASP5 may contribute to the development of RA by mediating inflammation.	29158166
Dermatitis	Altered Intercellular Communication	Specific deletion of suppressor of cytokine signaling 3 (Socs3) in keratinocytes can cause severe skin inflammation with infiltration of immune cells.	29158586
Inflammatory abnormality of the eye	Altered Intercellular Communication	Being a multifactorial disease, it is characterized by oxidative stress in the cornea and commonly complicated by ocular surface inflammation.	29158874
Inflammation, Observation Method - Coagulation, Endothelial dysfunction, Hemorrhagic Fever, Crimean	Altered Intercellular Communication	Evaluation of the associations between endothelial dysfunction, inflammation and coagulation in Crimean-Congo hemorrhagic fever patients.	29159591
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	There is no relationship between increased inflammation and endothelial dysfunction.	29159591
Inflammation, Pterygium Of Conjunctiva And Cornea	Altered Intercellular Communication	HBD-2 expression that might be stimulated by inflammatory cytokines may be related to inflammation and fibrovascular proliferation and may play a role in pterygium pathogenesis.	29160535
Inflammation, Amyloidosis, Carpal Tunnel Syndrome	Altered Intercellular Communication	The deposition of b2-microglobulin induced by reactive inflammation causing carpal tunnel syndrome (CTS) is one of the complications of dialysis-related amyloidosis in maintenance hemodialysis (MHD) patients.	29161700
Inflammation, Hypersensitivity, Tetanus	Altered Intercellular Communication	Most of the allergic reactions to tetanus toxoid vaccine usually present with unspecific symptoms of local inflammation.	29162425
Inflammation	Altered Intercellular Communication	This observational case-control study attempted to identify factors associated with TMJD development, particularly inflammation.	29162786
Autoimmune Diseases	Altered Intercellular Communication	In conclusion, autoimmune diseases and inflammatory conditions are associated with increased risk of TMJD.	29162786
Uveitic glaucoma	Altered Intercellular Communication	We identified uveitic glaucoma patients with AGV surgery alone and AGV surgery combined with fluocinolone implant from the Massachusetts Eye and Ear Ocular Inflammation Database.	29162989
Inflammation, Glaucoma, CTCAE	Altered Intercellular Communication	Compared to the AGV group, the AGV + fluocinolone group used fewer glaucoma medications (0.28 vs 1.30 [P = 0.01]) and had better inflammation control (P = 0.02).	29162989
Diverticulitis, Diverticulum, Colitis	Altered Intercellular Communication	Diverticular colitis is chronic inflammation of the colon where diverticula are present.	29164476
Malignant neoplasm of skin, Inflammatory disorder	Altered Intercellular Communication	To examine immunoreactivity to VDR and CYP24A1 in mast cells from normal human skin, keratinocyte skin cancers, and disorders of chronic inflammation.	29165303
Inflammation, Tumor necrosis	Altered Intercellular Communication	Immune homeostasis favored inflammation, and a negative correlation between the circulating tumor necrosis factor-alpha and the proportions of CD4+CD25+CD62L+ cells (r = -0.698, p < 0.05) in patients with AECOPD was found.	29166179
Fibrosis Assessment, Tissue Adhesions, Acute inflammation	Altered Intercellular Communication	The adjunct use of biologics (eg, viable umbilical tissue) may provide additional support and reduce postoperative inflammation, adhesions, and fibrosis.	29166259
Inflammation, Obesity	Altered Intercellular Communication	Low grade inflammation, potentially initiated by the intestinal microbiota, has been suggested to be a driving force in the development of insulin resistance in obesity.	29166392
Heredity, Traumatic injury, physiopathological	Altered Intercellular Communication	The etiology remains unknown, although factors such as trauma, hormonal dysfunction and heredity have been suggested.	29166520
Inflammation, Fever	Altered Intercellular Communication	Furthermore, he remained febrile and inflammation markers remained elevated despite antibacterial treatment.	29166922
Inflammation	Altered Intercellular Communication	Dysregulated inflammation is implicated in the pathobiology of aging, yet platelet-leukocyte interactions and downstream cytokine synthesis in aging remains poorly understood.	29167233
Inflammation, Bronchiectasis, Aortic Stiffness	Altered Intercellular Communication	In addition, we sought to compare these direct measures against calculated QRISK2 scores.Aortic stiffness, cardiac biomarkers and systemic inflammation were measured in 101 adults with stable bronchiectasis.	29167299
Inflammation, Symptom aggravating factors	Altered Intercellular Communication	In addition, frequent exacerbators had elevated serum C-reactive protein concentration, suggesting increased systemic inflammation (4.8 versus 2.2 mg*L-1, p=0.005).	29167299
Inflammation, Spinal Fractures	Altered Intercellular Communication	We demonstrated that trabecular bone score, a parameter of bone quality, was associated with systemic inflammation and was a significant determinant of vertebral fracture independent of bone mineral density.	29167970
Inflammation, Weight decreased	Altered Intercellular Communication	Systemic inflammation, as reflected by increased hsCRP levels, may be involved in deterioration of the trabecular microarchitecture in COPD-associated osteoporosis, whereas BMD decline is most strongly associated with weight loss.	29167970
Sleep-Disordered Breathing, Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	Sleep-disordered breathing (SDB) is associated with cardiovascular disease and systemic inflammation in adults but this remains to be explored in children, especially in children with the most common form of SDB, i.e.	29168015
Inflammation, Sleep-Disordered Breathing	Altered Intercellular Communication	This pilot study investigated the relationship between the cardiovascular function and inflammation in children with mild SDB.	29168015
Inflammation	Altered Intercellular Communication	Inflammation may play a role in TC in combination with or independently of excess weight.	29168186
Inflammation, Atherosclerosis	Altered Intercellular Communication	Biomarkers of inflammation such as high-sensitivity C-reactive protein (hs-CRP) associate with subclinical atherosclerosis.	29168363
Inflammation, Panuveitis, Retinitis, Vitritis, Hypopyon	Altered Intercellular Communication	A 26-year-old man presented with bilateral panuveitis (hypopyon in the right eye, bilateral anterior segment inflammation, vitritis and retinitis).	29170182
Vitritis, Inflammation, Hypopyon, Retinal Detachment	Altered Intercellular Communication	The second patient, a 28-year-old man, presented with bilateral anterior segment inflammation, vitritis, exudative retinal detachment and hypopyon in the right eye.	29170182
Inflammation, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Lp-PLA2 was a marker of oxidative stress and inflammation, rather than an independent risk factor for ACS in young Chinese patients.	29170433
methyldopa, Inflammation, Blindness	Altered Intercellular Communication	A chronic low-level inflammation contributes to the pathogenesis of age-related macular degeneration (AMD), the most common cause of blindness in the elderly in Western countries.	29170454
Inflammation	Altered Intercellular Communication	In contrast to previous findings, CB2 activation increased, rather than reduced inflammation in RPE cells.	29170454
Inflammation, Nasopharyngeal carcinoma	Altered Intercellular Communication	BMAL1 mRNA was significantly reduced in nasopharyngeal carcinoma (4.67 +- 0.27 versus 6.64 +- 0.51 in chronic inflammation tissues, p = 0.002).	29172799
Pharyngitis, Nasopharyngeal carcinoma	Altered Intercellular Communication	Level of BMAL1 mRNA was assessed in tissue specimens from 36 nasopharyngeal carcinomas and 20 nasopharyngeal chronic inflammations using quantitative reverse transcriptase-polymerase chain reaction.	29172799
Inflammation, Cerebrovascular accident	Altered Intercellular Communication	Immunity and inflammation predictors for short-term outcome of stroke in young adults.	29172921
Amyloidosis	Altered Intercellular Communication	Amyloid A amyloidosis is a rare complication of chronic inflammatory conditions.	29173691
Adenocarcinoma of lung (disorder)	Altered Intercellular Communication	To systematically evaluate the prognostic value of nutrition/inflammation-based markers for recurrence-free survival (RFS) in pN2-stage IIIA lung adenocarcinoma patients.	29173768
Adenocarcinoma of lung (disorder), Neoplasms	Altered Intercellular Communication	The CAR was the best prognostic marker to predict tumor recurrence in pN2-stage IIIA lung adenocarcinoma patients among the 7 nutrition/inflammation-based markers.	29173768
Inflammation, Poliovirus Vaccine, Inactivated, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases	Altered Intercellular Communication	IPV can significantly predispose women to a lifetime risk of developing cardiovascular disease (CVD) due to the effects of stress and inflammation.	29173932
Minimal Disseminated Disease	Altered Intercellular Communication	Together, these data implicate neuro-inflammation as playing a crucial role in MDD.	29175309
Inflammation, Myocarditis, CTCAE 5.0	Altered Intercellular Communication	However, it was debatable whether the hypervascularity demonstrated by coronary PMCTA in the case of acute myocarditis was more prominent than the vascular images obtained in other cases without inflammation.	29175582
atherosclerotic, Coronary heart disease	Altered Intercellular Communication	Although 18F-fluorodeoxyglucose (FDG) uptake has emerged as a sensitive and reliable marker of atherosclerotic inflammation, its additive predictive value for future coronary disease in older subjects is unknown.	29175654
malignant disease, Coronary Artery Disease, Arteritis	Altered Intercellular Communication	In older subjects with no history of malignant disease or overt coronary artery disease, arterial inflammation evaluated by FDG uptake provides information on future occurrence of coronary artery events.	29175654
Glioma	Altered Intercellular Communication	Significance of systemic immune-inflammation index in the differential diagnosis of high- and low-grade gliomas.	29175722
Inflammation	Altered Intercellular Communication	Growth arrest-specific gene 6 (Gas6) is secreted by endothelial cells and is important for the activation of endothelium during inflammation.	29176262
Inflammation, Fracture	Altered Intercellular Communication	Association of Insulin-like Growth Factor-1, Bone Mass and Inflammation to Low-energy Distal Radius Fractures and Fracture Healing in Elderly Women Attending Emergency Care.	29178313
Inflammation, Fracture, Traumatic injury	Altered Intercellular Communication	Postmenopausal women, 55 years or older, with low-energy distal radius fractures occurring due to falling on slippery ground, indoors or outdoors, were recruited in the emergency department (ED) and followed 1 and 5 weeks after the initial trauma with biomarkers for nutritional status and inflammation.	29178313
Inflammation, Fracture, Leukocytosis	Altered Intercellular Communication	Fracture healing was associated with initial leukocytosis and a lower thrombocyte count, suggesting that inflammation and thrombocytes are important components in fracture healing.	29178313
Gonadal Disorders, Adrenal cortical hypofunction	Altered Intercellular Communication	Congenital adrenal insufficiency with 46XY sex reversal is a rare disorder that is characterized by dysregulation of steroid hormone synthesis, leading to adrenal and gonadal dysfunction.	29178636
Autoimmune Diseases of the Nervous System, Lupus Erythematosus	Altered Intercellular Communication	systemic lupus erythematosus, however, to what extent they are present in autoimmune central nervous system inflammation has not yet been investigated.	29178933
Airway structure	Altered Intercellular Communication	Eight to ten weeks old BALB/cJ mice were exposed through the airways to particulate material, and markers of airway inflammation were determined.	29178979
Airway structure, AHR wt Allele	Altered Intercellular Communication	Baltimore PM induced more robust airway inflammation, AHR, and Th2 cytokine production, possibly due to the greater metal content in Baltimore PM.	29178979
Inflammation	Altered Intercellular Communication	Prognostic significance of procalcitonin might be implicated in inflammation.	29179592
PROS1 gene, Bone Marrow	Altered Intercellular Communication	This study aims to evaluate thresholding for quantification of subtle bone marrow inflammation in the spine and the sacroiliac (SI) joints of patients with PsA and compare it with the SPARCC scoring system.	29179748
Inflammation	Altered Intercellular Communication	A threshold was applied to visible bone marrow in order to mask areas with higher signal intensity, which are consistent with inflammation.	29179748
Hepatitis, Insemination, Artificial, Homologous	Altered Intercellular Communication	Current guidelines have defined biochemical remission (normalisation of biochemical markers for liver inflammation) as a major goal in the treatment of AIH.	29180000
Inflammation	Altered Intercellular Communication	Sterile inflammation is an immediate and well-coordinated immune response to surgical injury.	29180192
Inflammation	Altered Intercellular Communication	Induced inflammation stimulates the vagus nerve, which in turn activates anti-inflammatory nonneuronal processes.	29180192
Inflammation	Altered Intercellular Communication	The spleen is a major organ of the immune system playing an important role during inflammation.	29180192
Inflammation, Obesity, Diabetes Mellitus	Altered Intercellular Communication	Obesity-induced inflammation engenders insulin resistance and type 2 diabetes mellitus (T2DM) but the inflammatory effectors linking obesity to insulin resistance are incompletely understood.	29180649
Inflammation	Altered Intercellular Communication	In contrast, more HRDs, which might reflect increased inflammation in the retina, were observed in dexamethasone responders.	29183041
Trauma, Nervous System	Altered Intercellular Communication	Inflammation-associated and neuronal damage markers were measured in blood and cerebrospinal fluid (CSF) of HIV-infected children aged 8 to 18 years.	29183044
Trauma, Nervous System	Altered Intercellular Communication	Neuroretinal thinning was associated with inflammation-associated and neuronal injury biomarkers in a cohort of antiretroviral therapy-treated perinatally HIV-infected children.	29183044
Inflammation, Trauma, Nervous System	Altered Intercellular Communication	These findings suggest that ongoing immune activation, inflammation, and neuronal injury occur in parallel with retinal thinning in pediatric HIV.	29183044
Inflammatory Bowel Diseases, Gastrointestinal inflammation	Altered Intercellular Communication	Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal tract that is associated with changes in the gut microbiome.	29183332
Cholecystitis, Inflammation	Altered Intercellular Communication	We use open cholecystectomy (OC) to treat severe cholecystitis in cases in which we are worried that inflammation might cause anatomical changes in Calot's triangle.	29183521
Cholecystitis, Fibrosis Assessment, Inflammation	Altered Intercellular Communication	Furthermore, in cases of severe cholecystitis in which marked inflammation leads to fibrosis, we perform subtotal cholecystectomy (SC), i.e., incomplete gallbladder resection.	29183521
Inflammation, Chronic sinusitis, Craniosynostosis	Altered Intercellular Communication	Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by epithelial inflammation and tissue eosinophilic infiltration.	29186722
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1, polychondritis, Inflammation	Altered Intercellular Communication	Relapsing polychondritis is a rare multisystem autoimmune disease characterized by recurrent inflammation and destruction of different cartilaginous and proteoglycan-rich structures like cardiovascular system.	29187087
Inflammation, Carcinogenesis, leukemia	Altered Intercellular Communication	The matrix metalloproteinases (MMPs) are important in inflammation and carcinogenesis, and the genotypic role of MMP7 has never been examined in leukemia to date.	29187444
Inflammation, Atherosclerosis	Altered Intercellular Communication	Chronic inflammation and activation of the immune system, including B-lymphocyte maturation is believed to play a role in atherosclerosis.	29189047
Inflammation, Acute infectious disease	Altered Intercellular Communication	recurrent acute infections and low-grade chronic inflammation) on each affected nutrient biomarker.	29189196
Inflammation, Pain Distress Question	Altered Intercellular Communication	Alarmins in Frozen Shoulder: A Molecular Association Between Inflammation and Pain.	29190116
Inflammation	Altered Intercellular Communication	Ultra-wide-field fluorescence angiography (UWFA) was conducted on 13 patients, and peripheral vascular leakage was observed in 22/26 eyes (84.62%) compared with active anterior chamber inflammation in 13/26 eyes (50%).	29190160
Inflammation, Bipolar Disorder	Altered Intercellular Communication	The association between depressive symptoms and insulin resistance, inflammation and adiposity in men and women.	29190710
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Depression has been shown to be associated with elevated leptin levels, low-grade inflammation and insulin resistance.	29190710
Inflammation, Depressed mood, Diabetes Mellitus	Altered Intercellular Communication	A cross-sectional analysis was carried out on a cohort of 639 participants from the ADDITION-Leicester dataset to assess differences in markers of diabetes risk, cardiovascular risk and inflammation in depressed and non-depressed individuals.	29190710
Inflammation, Atherosclerosis	Altered Intercellular Communication	Elevated oxidized low-density lipoprotein (ox-LDL) and cell adhesion molecules are associated with inflammation and atherosclerosis.	29190851
Inflammation, Nerve Degeneration	Altered Intercellular Communication	JEV is associated with neurodegeneration, severe inflammation, increased oxidative stress and elevated levels of stress linked proteins.	29191708
Symptoms, Inflammation, Blood Vessel	Altered Intercellular Communication	The primary endpoint was time to relapse of TAK, defined as >=2 of the following: objective systemic symptoms, subjective systemic symptoms, elevated inflammation markers, vascular signs and symptoms or ischaemic symptoms.	29191819
Intrahepatic Cholangiocarcinoma	Altered Intercellular Communication	Prognostic Implication of Inflammation-based Prognostic Scores in Patients with Intrahepatic Cholangiocarcinoma Treated with First-line Gemcitabine plus Cisplatin.	29192354
Gastrointestinal inflammation	Altered Intercellular Communication	Fecal calprotectin (FC) is a marker of intestinal inflammation.	29192504
Intraepithelial Lymphocytes, Inflammation, Graft-vs-Host Disease, Bile duct structure, Damage, Cholestasis	Altered Intercellular Communication	Two hepatopathologists blindly evaluated 40 liver biopsies from patients with clinically and biologically confirmed graft-versus-host disease, as well as 44 controls, for percent bile duct loss, bile duct damage, intraepithelial lymphocytes, ductular reaction, acidophilic bodies/10 high power fields (HPF), cholestasis, portal and lobular inflammation, and endotheliitis.	29192646
Acute and chronic inflammation	Altered Intercellular Communication	A final histopathological diagnosis of ectopic brain tissue with neural tissue demonstrating focal, chronic T-cell inflammation was made.	29192861
Communicable Diseases, Inflammation	Altered Intercellular Communication	A distinct mechanism of senescence activation in amnion epithelial cells by infection, inflammation, and oxidative stress.	29193446
Communicable Diseases, Tumor necrosis, Inflammation	Altered Intercellular Communication	We investigated p38MAPK activation-induced fetal membrane cell senescence in response to inflammation (tumour necrosis factor-alpha [TNF-a]) and infection (lipopolysaccharide [LPS]), factors associated with spontaneous preterm birth.	29193446
Hepatic inflammation, Alcoholic Liver Diseases	Altered Intercellular Communication	Hepatic inflammation, triggered by activated Kupffer cells, is a driving force in alcoholic liver disease.	29193575
Inflammation, Injury of liver, Alcoholic Liver Diseases	Altered Intercellular Communication	Interleukin 37 transgenic mice are not protected against hepatic injury and inflammation in alcoholic liver disease.	29193575
Hepatic inflammation, Alcoholic Liver Diseases	Altered Intercellular Communication	Human recombinant Interleukin 37 ameliorated hepatic inflammation in a binge drinking model of alcoholic liver disease.	29193575
Inflammatory, Chronic sinusitis, Craniosynostosis, Olfactory Receptor Cells	Altered Intercellular Communication	Olfactory inflammation in chronic rhinosinusitis (CRS) is associated with cytokines that may result in the death of olfactory sensory neurons.	29193850
Acute and chronic inflammation	Altered Intercellular Communication	Activation of neuronal JNK is a feature of chronic olfactory inflammation that is associated with neuronal apoptosis.	29193850
Inflammation, ASAH1 gene	Altered Intercellular Communication	Both cellular and molecular (cytokines) inflammation play a key role after aSAH during the phase of occurrence of post-SAH complications.	29194369
Inflammation, Depression, CTCAE, Oral pain, Pain Distress Question	Altered Intercellular Communication	Considering that inflammation is associated with the pathophysiology of BMS, and that inflammation is closely associated with pain and depression, we aimed to correlate depressive symptomatology and oral cavity pain with plasma cytokine/chemokine signatures in a cohort of patients with BMS.	29194773
Inflammation, Neoplasms	Altered Intercellular Communication	This offers two potential pathways that may facilitate tumour progression - local inflammation promoting peritoneal adherence and implantation, and secondary suppression of immunosurveillance due to circulating inflammatory response.	29194906
Inflammation, Ischemic stroke, Cerebrovascular accident	Altered Intercellular Communication	Background Procarboxypeptidase U (proCPU, TAFI, proCPB2), the zymogen of CPU, which is a potent antifibrinolytic enzyme and a modulator of inflammation, has previously been investigated in plasma of stroke patients, but so far, no information on the proCPU levels in cerebrospinal fluid (CSF) during acute ischemic stroke (AIS) is available.	29194929
Inflammation, Pain Distress Question, palladium, Fibrosis Assessment, Peyronie Disease, Connective Tissue Diseases	Altered Intercellular Communication	Peyronie's disease (PD) is an acquired connective tissue disorder of the tunica albuginea with fibrosis and inflammation that lead to palpable plaques formation, penile curvature, and pain during erection.	29195031
Inflammation, Autonomic neuropathy, Canada	Altered Intercellular Communication	Biomarkers of inflammation and adiponectin are associated with cardiovascular autonomic neuropathy (CAN) in cross-sectional studies, but prospective data are scarce.	29195493
Inflammation, Neurogenic arthropathy, Diabetes Mellitus	Altered Intercellular Communication	Bone mineral density and markers of bone turnover and inflammation in diabetes patients with or without a Charcot foot: An 8.5-year prospective case-control study.	29196119
Inflammation, Hemorrhagic, COL4A2 wt Allele, Brain hemorrhage	Altered Intercellular Communication	Higher S100A12 concentrations are positively associated with inflammation, hemorrhagic severity and short-term mortality among ICH patients, indicating S100A12 may represent a biomarker for predicting poor outcome after hemorrhagic stroke.	29196185
Pain Distress Question, Inflammation, Depression, CTCAE	Altered Intercellular Communication	Opioid usage was more likely to be associated with subjective measures (depression, BASDAI, BASFI) than objective measures (CRP, ESR), suggesting that pain in AS may derive from sources other than spinal inflammation alone.	29196383
Erectile dysfunction, Tuberculosis, Atherosclerosis	Altered Intercellular Communication	No previous studies have investigated the prevalence of latent tuberculosis infection (LTBI) among patients with erectile dysfunction (ED) or its contribution to the development of high-grade ED through a process of chronic inflammation-induced atherosclerosis.	29196694
Inflammation, Aggressive behavior, Obesity, Visceral	Altered Intercellular Communication	Visceral obesity is considered to be associated not only with chronic systemic inflammation but also with aggressive cancer behavior.	29196841
Inflammation, Atherosclerosis	Altered Intercellular Communication	Lipoxygenases (LOXs) and their genes are of critical importance in oxidative stress, inflammation, and atherosclerosis.	29196930
Inflammation, Depression, CTCAE	Altered Intercellular Communication	Whilst there is evidence of an association between depression and inflammation in adults, there is limited data on this in adolescents particularly in non-westernized populations.	29197794
Inflammation, Depression, CTCAE	Altered Intercellular Communication	The cross sectional study design does not allow us to conclude that there is a direct relationship between inflammation and depression, and this would need to be tested in an intervention study.	29197794
Inflammation, Ischemic stroke	Altered Intercellular Communication	Exposure to cadmium has been associated with carotid plaques, inflammation in carotid plaques, and increased risk of ischemic stroke.	29197829
Inflammation, Congestive heart failure	Altered Intercellular Communication	At the same time, anti-inflammatory cytokines such as IL-10 may neutralize inflammation in CHF.	29198133
Inflammation, FOXP3 gene, Congestive heart failure	Altered Intercellular Communication	Although inflammation plays a central role in the pathophysiology of CHF, the roles of FOXp3, RORgt, and IL-10 remain to be determined (Tab.	29198133
Communicable Diseases, Oligospermia	Altered Intercellular Communication	After excluding viral, infectious, genetic and anatomical causes of the subject's oligoasthenoteratozoospermia, we performed a hormonal analysis to verify our hypothesis.	29198592
Cessation of life, Inflammation	Altered Intercellular Communication	However, little is known about systemic inflammation in kidney donors and, notably, brain death causes a strong systemic inflammatory response.	29198657
Inflammation, Oral lesion	Altered Intercellular Communication	One individual demonstrated reduction in palatal inflammation and another one did not show improvement in the oral lesion.	29198763
Candidemia, Inflammation	Altered Intercellular Communication	Chemokine CXCL13 is well-known involved in inflammation, but its role in candidemia has not been assessed.	29198822
Inflammation, Rheumatoid Arthritis, Disease	Altered Intercellular Communication	Remaining local subclinical joint inflammation is associated with deteriorated metacarpeal head bone microarchitecture in rheumatoid arthritis patients low disease activity.	29198886
Inflammation	Altered Intercellular Communication	They were divided in two groups according to local inflammation assessed by Doppler-ultrasound exam surrounding the site of erosion.	29198886
Refractory anemias, Inflammation, Disease	Altered Intercellular Communication	In RA patients in low disease activity under bDMARDs, persistence of local inflammation was associated with alteration of the trabecular compartment.	29198886
Data types - Address, physiopathological	Altered Intercellular Communication	The time course of altered synaptic transmission mimics the spread of pathology through hippocampus in human AD and provides support for this model as a valuable preclinical tool in elucidating pathological mechanisms of early synapse dysfunction in AD.	29199135
Inflammation, Arthritis, Infectious, septic	Altered Intercellular Communication	Wrist inflammation: a retrospective comparison between septic and non-septic arthritis.	29199508
Inflammation, Arthritis, Infectious	Altered Intercellular Communication	This study aims to identify differences in demographics, clinical and laboratory data between wrist septic arthritis and non-septic arthritis in patients admitted for wrist inflammation.	29199508
Inflammation, Arthritis, Infectious	Altered Intercellular Communication	In patients with isolated wrist inflammation, the mean C-reactive protein in the septic arthritis group was significantly higher compared with the non-septic arthritis group (mean difference 132 mg/L, 95% CI 30.9-234).	29199508
Inflammation, Impaired cognition, "Alzheimers Disease	Altered Intercellular Communication	Inflammation has been linked to clinical cognitive impairment, including Alzheimer's disease.	29199872
Inflammation	Altered Intercellular Communication	Less is known, however, about the relationship between inflammation and normal, age-associated cognitive decline.	29199872
Inflammation	Altered Intercellular Communication	This study investigated whether biomarkers of inflammation were associated with cognitive function and decline in older Taiwanese adults.	29199872
Inflammation, Impaired cognition	Altered Intercellular Communication	This study did not support a causal link between inflammation and cognitive decline among this older cohort.	29199872
Refractory anemias, Rheumatoid Arthritis, Inflammation, Inflammatory disorder	Altered Intercellular Communication	Rheumatoid arthritis (RA) is a systemic inflammatory disease that causes chronic inflammation of the joints.	29200952
Inflammation	Altered Intercellular Communication	Structured reporting for tubular inflammation showed excellent agreement (kappa = 1), but no other subdomain demonstrated better than moderate agreement (kappa < 0.6).	29202260
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	Inflammation has been hypothesised to be a link between PTSD and the most common co-morbid medical disorders.	29202383
Post-Traumatic Stress Disorder, Inflammation	Altered Intercellular Communication	However, the relationship between inflammation and PTSD is not clear.	29202383
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Angiotensin-converting enzyme defines matrikine-regulated inflammation and fibrosis.	29202450
Inflammation	Altered Intercellular Communication	Pulmonary ACE is elevated during episodes of acute inflammation, as a consequence of enhanced vascular permeability, to ensure the efficient degradation of AcPGP.	29202450
ARCN1 gene, Inflammation, Fibrosis Assessment, Idiopathic Pulmonary Fibrosis	Altered Intercellular Communication	Thus, AcPGP seemingly has very divergent roles: it is pathogenic in its capacity to drive neutrophilic inflammation and matrix degradation in the context of COPD, but it is protective in its capacity to limit fibrosis in IPF.	29202450
Inflammation, Postexertional fatigue, Anxiety, CTCAE 3.0, Depression, CTCAE, Fatigue	Altered Intercellular Communication	Clinical markers consisted of questionnaire scores for symptoms of post-exertional malaise, inflammation, fatigue, depression and trait anxiety, as well as activity recordings.	29202780
Inflammation, Asthma	Altered Intercellular Communication	In this community based population, non-eosinophilic asthma was common, less severe than EA, and at baseline most asthmatics showed no evidence of inflammation.	29202821
Mycosis Fungoides, Inflammation, Venous Thromboembolism, vinyltriethoxysilane	Altered Intercellular Communication	Mycosis fungoides (MF) and parapsoriasis are characterized by malignant proliferation and chronic inflammation, which may affect the risk for venous thromboembolism (VTE).	29203438
Proctitis	Altered Intercellular Communication	Metronidazole improved her abdominal symptoms, as well as her colonoscopic and histopathological findings, suggesting that HIS was responsible for her colorectal inflammation.	29204849
Inflammation, Kidney Diseases, diabetic	Altered Intercellular Communication	Inflammation plays a key role in DN, and pentosan polysulfate (PPS) has been shown to largely attenuate the inflammation of nephropathy in aging diabetic mice.	29207166
Inflammation, Hyperglycemia	Altered Intercellular Communication	p38 mitogen-activated protein kinase (p38 MAPK) plays a crucial role in tissue inflammation and cell apoptosis, and it is activated by hyperglycemia.	29207166
Inflammation	Altered Intercellular Communication	Distinct Roles of Endothelial Dysfunction and Inflammation in Intracranial Atherosclerotic Stroke.	29207392
Inflammation, Endothelial dysfunction	Altered Intercellular Communication	Markers of endothelial dysfunction (asymmetric dimethylarginine, ADMA) and inflammation (lipoprotein-associated phospholipase A2, Lp-PLA2) were measured.	29207392
Inflammation, Acute infarct, Endothelial dysfunction	Altered Intercellular Communication	Endothelial dysfunction and inflammation have distinct effects in ICAS patents; endothelial dysfunction is associated with the underlying micro- and macro-atherosclerotic burden, whereas inflammation is associated with acute infarct volume and pattern.	29207392
Pancreatic Diseases, Inflammation	Altered Intercellular Communication	Recent studies indicate that the sphingolipid signaling pathway may be one of the important factors contributing to the development of inflammation in pancreatic diseases.	29207545
Cytomegalovirus Infections, Inflammation, Epithelial	Altered Intercellular Communication	The remarkable histological feature of CMV infection appeared to be significant acute inflammation in addition to apoptotic epithelial injuries, and particularly in an early stage of CMV replication, acute inflammation is possibly the only detectable feature of CMV infection.	29207904
Retinitis	Altered Intercellular Communication	Fluorescein angiography (FA) showed nonspecific retinal inflammation, and an electroretinogram (ERG) illustrated decreased amplitude of the b wave in both eyes.	29207977
Barrett Esophagus, Inflammation, Esophagitis, Esophageal carcinoma	Altered Intercellular Communication	Considerable evidence supports a major role for chronic inflammation and diverse chemokine pathways in the development of Barrett's esophagus and esophageal adenocarcinoma.Experimental Design: Here we utilized an IL1b transgenic mouse model of Barrett's esophagus and esophageal adenocarcinoma and human patient imaging to analyze the importance of CXCR4-expressing cells during esophageal carcinogenesis.Results: IL1b overexpression induces chronic esophageal inflammation and recapitulates the progression to Barrett's esophagus and esophageal adenocarcinoma.	29208671
Inflammation, Infection caused by Helicobacter pylori, Eyelid Xanthoma, Carcinogenesis, physiopathological	Altered Intercellular Communication	Current study described a large xanthelasma cohort in Chinese population, revealed its relationship with H. pylori infection, carcinogenesis, metabolic dysfunction and inflammation as well.	29209116
Inflammation, Histoplasmosis	Altered Intercellular Communication	Post-mortem examination revealed that her ileo-colonic inflammation was caused by Histoplasmosis.	29209121
Inflammation, Diarrhea, Ulcerative Colitis	Altered Intercellular Communication	Ulcerative colitis (UC) is a chronic inflammation of the large bowel characterized by diarrhea and a negative stool culture.	29211811
FTO protein, human, Obesity	Altered Intercellular Communication	FeNO might help to identify patients with eosinophilic inflammation-driven asthma, whereas patients with low FeNO might have an obesity-associated asthma phenotype in which symptoms are partly caused by the obesity.	29212496
Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn	Altered Intercellular Communication	Sepsis-associated acute respiratory distress syndrome (ARDS) is characterized by neutrophilic inflammation and poor survival.	29212955
Inflammation, Congenital bilateral aplasia of vas deferens	Altered Intercellular Communication	In our present work, complex connections among mechano-response, oxidative stress, inflammation and extracellular remodeling pathways in the etiology of CAVD were revealed.	29212967
vascular inflammations	Altered Intercellular Communication	The total vascular inflammation score (TVIS), angiogenesis score (AS), and numbers of VEGF-expressing and TNF-a-expressing cells were analyzed in the fascia and muscle.	29216907
Inflammation	Altered Intercellular Communication	The fascia can therefore be a primary site of inflammation and angiogenesis in the pathogenesis of DM.	29216907
Refractory anemias, Inflammation, Destruction of tissue	Altered Intercellular Communication	In the course of RA, the BM microenvironment can promote the development of Th17 cell responses and overproduction of IL-17AF that may lead to increased inflammation and tissue destruction in RA BM.	29216915
Congenital leptin deficiency, Hyperphagia, Obesity	Altered Intercellular Communication	The most common of the single gene alterations affect the leptin gene (LEP), resulting in congenital leptin deficiency that manifests as intense hyperphagia, EOO and severe obesity associated with hormonal and metabolic alterations.	29217499
Inflammation, Hyphema	Altered Intercellular Communication	There were no complications including hyphema, peripheral anterior synechia formation nor prolonged inflammation throughout the follow-up period.	29218423
Inflammation, Lesion of cervix	Altered Intercellular Communication	Due to the accompanying and often obscuring lymphocytic inflammation, malignant cells may be difficult to recognize on cytologic samples and can mimic several more common benign and atypical cervical lesions.	29218797
Inflammation, Periodontitis, Non-alcoholic Fatty Liver Disease, Diabetes Mellitus	Altered Intercellular Communication	NAFLD, periodontitis and diabetes share common risk factors, are characterised by inflammation and associated with changes in commensal bacteria.	29220367
Nephritis, Chronic Kidney Diseases	Altered Intercellular Communication	Total flavones extracted from Abelmoschus manihot L. (Malvaceae) medic (TFA) have been proven clinically effective at improving renal inflammation and glomerular injury in chronic kidney disease (CKD).	29221422
Nephritis	Altered Intercellular Communication	Our results show that TFA could dose-dependently ameliorate renal inflammation by inhibiting the activation of iRhom2/TACE signalling and attenuating ER stress.	29221422
Inflammation	Altered Intercellular Communication	d-Deprenyl when used as a positron emission tomography tracer visualizes peripheral inflammation.	29221756
Inflammation, Hypertension, CTCAE, Diabetes Mellitus, Non-Insulin-Dependent	Altered Intercellular Communication	Inflammation in the Prediction of Type 2 Diabetes and Hypertension in Healthy Adults.	29221802
Inflammation, Hypertension, CTCAE, Diabetes Mellitus, Non-Insulin-Dependent, Obesity	Altered Intercellular Communication	While inflammation is associated with obesity and insulin resistance, their inter-relationships in the development of type 2 diabetes or hypertension are not clear.	29221802
Vasculitis, Axonal degeneration	Altered Intercellular Communication	Nerve biopsies (n = 2) showed microvascular inflammation with axonal degeneration.	29222126
Dermatitis, Atopic, Data types - Address, Dermatitis, Pain of skin, Pruritus	Altered Intercellular Communication	Atopic dermatitis (AD) is associated with itch, skin inflammation and barrier disruption, and scratching, all of which may be associated with skin pain.	29223299
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Low-grade systemic inflammation: a partial mediator of the relationship between diabetes and lung function.	29223510
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Our results suggest that low-grade systemic inflammation could only explain a small part of the relationship between diabetes and lung function.	29223510
Inflammation, Impaired cognition, Nerve Degeneration	Altered Intercellular Communication	Chronic low-grade inflammation during aging (inflammaging) is associated with cognitive decline and neurodegeneration; however, the mechanisms underlying inflammaging are unclear.	29223680
Inflammation, Impaired cognition, Nerve Degeneration	Altered Intercellular Communication	Chronic low-grade inflammation during aging (inflammaging) is associated with cognitive decline and neurodegeneration; however, the mechanisms underlying inflammaging are unclear.	29223680
Inflammation	Altered Intercellular Communication	These findings support the association of peripheral inflammation, as demonstrated by CXCL10, in aging and cognitive decline.	29223680
vascular inflammations, Lipid Metabolism Disorders	Altered Intercellular Communication	Available data supports the conclusion that e-waste-exposed children with higher BPbs and concomitant abnormal measures of cardiovascular physiology have an augmented prevalence of vascular inflammation, as well as lipid disorder.	29223817
Inflammation, Kidney Failure, Acute, Endothelial dysfunction	Altered Intercellular Communication	Inflammation, oxidative stress, and endothelial dysfunction and damage play important roles in the development of AKI.	29223955
Otosclerosis, Inflammation, Paget Disease	Altered Intercellular Communication	Microcavitations found in periosteal and endosteal layers of human temporal bone specimens without otosclerosis, Paget's disease, or inflammation as reported in the current study are consistent with osteoclastic bone resorption.	29224005
Inflammation, Deficiency of butyryl-CoA dehydrogenase, Affection	Altered Intercellular Communication	Our findings first strengthen the hypothesis that inflammation critically impacts on the occurrence of sCAD, and second linked this condition with a marked affection of the coagulation system.	29224120
Thrombophilia, Familial cervical artery dissection	Altered Intercellular Communication	Spontaneous cervical artery dissection is accompanied by a hypercoagulable state and simultaneous inflammatory condition.	29224120
Inflammation, Hemorrhage, diabetic	Altered Intercellular Communication	Furthermore, we observed a reduction of spontaneous central bleeding and inflammation after PP treatment in diabetic mice.	29224179
Multiple Endocrine Neoplasia, Hyperparathyroidism, Primary, Menin	Altered Intercellular Communication	Primary hyperparathyroidism is the most common hormonal manifestation associated with multiple endocrine neoplasia 1 (MEN1).	29225207
Inflammatory Bowel Diseases, Inflammation, Malnutrition, Anemia	Altered Intercellular Communication	The aim of this study was to test hypothesis that transferrin, coinfluenced by inflammation, malnutrition, anemia, and oxidative stress, may better reflect global IBD patient's condition than any other more specific index.	29226154
Inflammatory Bowel Diseases, Inflammation, Malnutrition, Ulcerative Colitis, Anemia, Crohn Disease	Altered Intercellular Communication	Transferrin and other indices of inflammation, anemia, malnutrition, and oxidative stress were measured in 137 IBD patients (Crohn's disease (CD): n = 63 and ulcerative colitis (UC): n = 74) and 97 controls.	29226154
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	The associations with inflammation and anemia/malnutrition were more pronounced in UC and with oxidative stress in CD.	29226154
Inflammation	Altered Intercellular Communication	This result confirmed that periodontal inflammation might be a contributive factor of MetS.	29226321
Inflammation, Malnutrition	Altered Intercellular Communication	Eventually, our study associates low hArg concentrations with chronic low-grade inflammation and parameters of malnutrition in cardiovascular high-risk patients.	29226642
Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation	Altered Intercellular Communication	Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation and pro-inflammatory cytokines production.	29226727
Acute inflammation, Platelet aggregation test result	Altered Intercellular Communication	These data demonstrate a novel dynamic variation in platelet aggregation with acute vascular inflammation, including AA-induced whole blood clotting which is apparently COX-1 independent.	29227173
Inflammation	Altered Intercellular Communication	Oxidative stress from cigarette smoke and chronic inflammation is likely to induce this corticosteroid insensitivity.	29227717
Arthritis, Psoriasis	Altered Intercellular Communication	Circulating IFNg-producing CD8+ T-cells are raised in PsA when compared to psoriasis, suggesting a potential pathogenetic involvement of CD8+ T-cells and IFNg production in chronic joint inflammation and damage.	29228429
Inflammation, Tuberculosis, Necrosis	Altered Intercellular Communication	23% were known cases of tuberculosis with some cytological findings including inflammation, necrotic calcified deposits, multinucleated giant cell and reserve cell hyperplasia.	29228529
Inflammation, Basal cell hyperplasia	Altered Intercellular Communication	19% were pneumonic patients with smears demonstrating inflammation, curschmann's spiral and reserve cell hyperplasia.	29228529
Lupus Erythematosus, Systemic, Granulomatous inflammation, Sarcoidosis, Hydatid cyst (organism), Rheumatoid Arthritis, Lung Diseases, Interstitial, Chronic kidney disease stage 5, Heart failure, Asthma	Altered Intercellular Communication	Other non-neoplastic cases included in this study were asthma, granulomatous inflammation, rheumatoid arthritis, sarcoidosis, Wegener, SLE, heart failure, hydatid cyst, interstitial lung disease, and end stage renal disease.	29228529
Tissue damage, Inflammation	Altered Intercellular Communication	Collectively, our findings imply that NOX4 mediates ROS production in radiation-induced senescent cells and contributes to normal tissue damage after IR via the recruitment of inflammatory cells and the exacerbation of tissue inflammation.	29228832
Inflammation, Metallosis, Pseudotumor, Necrosis, Periprosthetic Fractures	Altered Intercellular Communication	ARMD consists of a wide range of alterations in periprosthetic tissues, most important of which are metallosis, inflammation, pseudotumors and necrosis.	29228956
Inflammation, Diego blood group system	Altered Intercellular Communication	Gradual spreading of inflammation to the infundibulum after RCC removal was considered as 1 possible mechanism of this delayed DI development.	29229338
Fibrosis Assessment, Hepatitis	Altered Intercellular Communication	Plasma cfDNA levels were associated with the degree of liver inflammation, body mass index, and alpha-fetoprotein (AFP) level, but were not associated with fibrosis stages.	29229500
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	Chronic inflammation in OA is a relevant factor in the development of cellular senescence and joint degradation.	29230269
Inflammation, Alcohol abuse	Altered Intercellular Communication	Elevated inflammation in association with alcohol abuse among Blacks but not Whites: results from the MIDUS biomarker study.	29230616
Inflammation, selenium, Alcohol abuse	Altered Intercellular Communication	Race moderated the association between alcohol abuse and CRP (b = 0.56, SE = 0.28, p = 0.048), IL-6 (b = 0.65, SE = 0.22, p = 0.004), and a composite inflammation score (b = 0.014, SE = 0.07, p = 0.041).	29230616
Inflammation, Obesity	Altered Intercellular Communication	This finding underlines the role that obesity plays in inflammation and autoimmune conditions.	29231278
Inflammation, Bladder Neoplasm	Altered Intercellular Communication	The bladder wall may thicken resulting from chronic inflammation after initial treatment (transurethral resection [TUR] or neoadjuvant chemotherapy), which may mimic the feature of recurrent or residual bladder tumors (RBT).	29232021
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Syndecan-4 is a transmembrane glycoprotein associated with inflammation and fibrosis.	29232393
Arterial Stiffness, Inflammation, Lupus Erythematosus	Altered Intercellular Communication	Association of Resting Heart Rate With Arterial Stiffness and Low-Grade Inflammation in Women With Systemic Lupus Erythematosus.	29232972
Arterial Stiffness, Inflammation	Altered Intercellular Communication	Resting heart rate (RHR) is associated with arterial stiffness, inflammation, and cardiovascular (CV) and all-cause mortality in the general population and in patients at high CV risk.	29232972
Inflammation, Adverse event, Atherosclerosis	Altered Intercellular Communication	Epicardial adipose tissue density and volume are related to subclinical atherosclerosis, inflammation and major adverse cardiac events in asymptomatic subjects.	29233634
Inflammation, Calcification of coronary artery, Dental Plaque, Eating	Altered Intercellular Communication	Lower EAT density and increased EAT volume were associated with coronary calcification, serum levels of plaque inflammatory markers and MACE, suggesting that dysfunctional EAT may be linked to early plaque formation and inflammation.	29233634
Refractory anemias	Altered Intercellular Communication	Such US features may have low specificity in inflammatory conditions affecting joints and enthesis such as SpA and RA.	29233691
Inflammation, Odontogenic Cysts	Altered Intercellular Communication	The diagnostic process can sometimes be hindered by tissue inflammation of KCOTs with loss of defining criteria, resulting in misdiagnosis as an odontogenic jaw cyst.	29233700
Nephritis	Altered Intercellular Communication	In biopsy tissues, CD147 induction was detected in injured lesions representing renal inflammation.	29234893
HSP90AA1 wt Allele, Nephritis, IGA Glomerulonephritis	Altered Intercellular Communication	Plasma CD147 values correlated with eGFR in patients with inflammation-related kidney diseases such as IgAN, HSPN, and DKD.	29234893
Inflammation, Cardiac Arrhythmia, Tachycardia, Ventricular	Altered Intercellular Communication	During a 6-week postablation "blanking period" (when arrhythmias may occur owing to postablation inflammation), there were 680 episodes of ventricular tachycardia.	29236642
Contusions, Glossitis	Altered Intercellular Communication	In addition, itching, dry skin, easy bruising, pigmentation, papulopustules on face, periungual inflammation, nail changes, and palmoplantar lesions were associated with significantly higher DLQI scores.	29237254
Glossitis	Altered Intercellular Communication	Periungual inflammation and palmoplantar lesions scored the highest DLQI.	29237254
Inflammation, Lung Injury	Altered Intercellular Communication	In various animal models of lung injury, HA has been shown to play a mechanistic role in modulating inflammation and injury.	29237497
Polymyositis, Inflammation	Altered Intercellular Communication	Roles of macrophage migration inhibitory factor in polymyositis: Inflammation and regeneration.	29239244
Inflammation, Polymyositis	Altered Intercellular Communication	Conclusion MIF and IL-6 play important roles in the inflammation associated with polymyositis.	29239244
Asthma	Altered Intercellular Communication	This may indicate that age may contribute to pulmonary function impairment in asthmatic women independently of their hormonal status at the time of asthma diagnosis.	29240514
Inflammation, Dental Plaque	Altered Intercellular Communication	In all cases, inflammation was most severe in the upper two-thirds of the dermis, and the differences in pustulopapular and plaque lesions were more prominent in the peri-inflammation area.	29240822
Inflammation, Anemia, Chronic Kidney Diseases	Altered Intercellular Communication	The pathogenesis of chronic kidney disease associated anemia is multifactorial and includes decreased production of erythropoietin (EPO), iron deficiency, inflammation, and EPO resistance.	29241199
Inflammation, atherosclerotic, Atherosclerosis	Altered Intercellular Communication	The Neutrophil-to-Lymphocyte Ratio (NLR), an index of systemic inflammation, has been reported to be associated with subclinical atherosclerosis, but its predictive role of the presence of carotid atherosclerotic plaques remains undefined.	29241668
Communicable Diseases, Inflammation, Traumatic injury, Inflammatory disorder	Altered Intercellular Communication	The Eph/ephrin receptor ligand system is known to play a role in inflammation induced by infection, injury, and inflammatory diseases.	29242524
Eosinophilic disorder, IgG4-Related Sclerosing Disease	Altered Intercellular Communication	IgG4-related disease (IgG4-RD) is a rare fibro-inflammatory condition that can affect almost any organ, characterized by tumefactive lesions and often by eosinophilia and elevated serum IgG4 concentrations.	29243036
Inflammation, Rheumatoid Arthritis	Altered Intercellular Communication	Association between urinary sodium and potassium excretion and blood pressure and inflammation in patients with rheumatoid arthritis.	29243056
Refractory anemias, Inflammation	Altered Intercellular Communication	Patients with RA have many comorbidities associated with salt sensitivity, but their salt intake and its relationship to blood pressure and inflammation is unknown.	29243056
Autistic behavior, Inflammation, Electrocardiogram: myocardial infarction (finding), Post-Traumatic Stress Disorder	Altered Intercellular Communication	Background Myocardial infarction-triggered acute stress disorder (ASD) and subclinical inflammation associate with the development of posttraumatic stress disorder, and worsen the prognosis of myocardial infarction patients.	29243511
Inflammation, fibrogenesis	Altered Intercellular Communication	Galectin-3 (Gal-3), a biomarker of inflammation, tissue repair and fibrogenesis, is associated to left ventricular remodeling after ST-elevated myocardial infarction (STEMI), but its relation with long-term outcomes is unclear.	29243525
Inflammation, Neoplasms	Altered Intercellular Communication	Tumor was reported to correlate with inflammation and the host's inflammatory response to tumor has been shown to independently predict the outcome.	29243802
Inflammation, Allergy - Charge Type Reason	Altered Intercellular Communication	MDT prepared the wound bed to receive skin autograft, successfully, without any interaction, allergy, or inflammation.	29244970
Communicable Diseases, Inflammation	Altered Intercellular Communication	But we can learn that foreign body should be one of consideration for the origin of inflammation or infection of soft tissues even there is not any laceration and penetration injuries.	29245255
SLC26A5 gene, Inflammation, Hemorrhage	Altered Intercellular Communication	PRES may be related to postpartum hemorrhage, blood pressure fluctuation, inflammation, and contrast agents.	29245268
Aggressive course, Inflammation, Behcet Syndrome, In-Stent Restenosis Indicator	Altered Intercellular Communication	Coronary artery involvement of Behcet disease warrants more attention and investigation; repeated in-stent stenosis, aggressive progress, and elevated inflammation markers should be regard with more care earlier in clinical practice.	29245339
Inflammation, Arterial aneurysm, Depression, CTCAE	Altered Intercellular Communication	After a 3-month treatment, follow-up examination showed a depression of the inflammation and a slight decrease of the arterial aneurysms.	29245353
Inflammation, Sleep Apnea, Obstructive	Altered Intercellular Communication	Finally, we arrived at a conclusion that serum d-lactate was increased in nonobese middle-aged males with obstrutive sleep apnea, possibly suggesting existence of subclinical disruption of intestinal barrier, and showed significant associations with inflammatory mediators, possibly being involved in systemic inflammation of obstructive sleep apnea.	29245360
Inflammation, Communicable Diseases, Herpes Simplex Infections, Chlamydia trachomatis, Lesion of cervix	Altered Intercellular Communication	Some sexually transmitted infectious agents, such as Chlamydia trachomatis and Herpes simplex, cause local inflammation, and could contribute to Human Papillomavirus (HPV) and cervical lesion progression.	29246195
Infarction, Myocarditis, Traumatic injury	Altered Intercellular Communication	Myocardial inflammation, injury and infarction during on-pump coronary artery bypass graft surgery.	29246240
Myocarditis	Altered Intercellular Communication	Myocardial inflammation and injury occur during coronary artery bypass graft (CABG) surgery.	29246240
Joint Task Force Type 1 Myocardial Infarction, Myocarditis	Altered Intercellular Communication	USPIO-defined cellular myocardial inflammation ranged from normal to those associated with type 1 myocardial infarction (median 80.2 [IQR 67.4 to 104.8] /s).	29246240
Inflammation, Myocarditis	Altered Intercellular Communication	LGE was associated with the delayed 24-h peak in hs-cTnI and its magnitude correlated with AUC plasma hs-cTnI concentrations (r = 0.33, p < 0.01) but not systemic inflammation, myocardial inflammation or bypass time.	29246240
Airway structure, Pulmonary function tests, Cystic Fibrosis	Altered Intercellular Communication	Patients with cystic fibrosis (CF) have airway inflammation that contributes to symptoms and to pulmonary function derangement.	29246256
ARCN1 gene, Inflammation, Pulmonary Emphysema	Altered Intercellular Communication	Platelet activation reduces pulmonary microvascular blood flow and contributes to inflammation; these factors have been implicated in the pathogenesis of COPD and emphysema.	29246770
Inflammation, Necrosis	Altered Intercellular Communication	The pathologic findings showed that although ischemic change (P = 0.43) and necrosis (P = 0.79) were observed in both groups, perivascular inflammation was observed only in the NBCA group (P = 0.006).	29246879
Airway structure	Altered Intercellular Communication	Staphylococcus aureus controls interleukin-5 release in upper airway inflammation.	29247803
Inflammation, Infection	Altered Intercellular Communication	Most of these infections are associated with milder inflammation compared to normal.	29248323
Inflammation, Neoplasms, Necrosis	Altered Intercellular Communication	In ten patients (0.5%), GBC was identified, each with an associated macroscopic finding, including local hardness (n = 1), a thickened wall (n = 5), acute inflammation and necrosis (n = 1), or suspected neoplasia (n = 3).	29248400
Inflammation, Pain Distress Question	Altered Intercellular Communication	Fibroblasts Promote Inflammation and Pain via IL-1a Induction of the Monocyte Chemoattractant Chemokine (C-C Motif) Ligand 2.	29248462
Inflammation	Altered Intercellular Communication	Using a combination of tissue protein expression profiling and bioinformatics, we discovered that many months after TKA, the fibrotic joint exists in a state of unresolved chronic inflammation.	29248462
Inflammation, Pain Distress Question	Altered Intercellular Communication	We propose that an IL-1a-NF-kB-CCL2 signaling pathway, operating within scar-associated fibroblasts, may be therapeutically manipulated for alleviating inflammation and pain in fibrotic joints and other tissues.	29248462
Inflammation, "Alzheimers Disease", Lewy Bodies, Dementia	Altered Intercellular Communication	Peripheral inflammation in prodromal Alzheimer's and Lewy body dementias.	29248892
Neurodegenerative Disorders, Inflammation, Lewy Bodies, Presenile dementia, "Alzheimers Disease", dendritic lamellar body, Data types - Address	Altered Intercellular Communication	There is growing evidence for the role of systemic inflammation in Alzheimer's disease (AD) and other neurodegenerative diseases; however the systemic inflammatory profile in dementia with Lewy bodies (DLB) has never before been investigated.	29248892
Inflammation, dendritic lamellar body, Data types - Address	Altered Intercellular Communication	We have shown for the first time that in both DLB and AD, increased peripheral inflammation occurs early at the MCI disease stages.	29248892
Inflammation	Altered Intercellular Communication	These data support a role for inflammation early in the disease process, and have important implications for the stage of disease where trials of anti-inflammatory medication should be focused.	29248892
Inflammation, Avascular necrosis of bone	Altered Intercellular Communication	Cytotoxic drugs may produce perivascular inflammation and ischemic necrosis.	29252181
Inflammation, Catatonia, Congenital Abnormality	Altered Intercellular Communication	Here, we showed that the underlying cause of catatonic signs is the low-grade inflammation of white matter tracts, which marks a final common pathway in Cnp-deficient and other mutant mice with minor myelin abnormalities.	29252214
Inflammation	Altered Intercellular Communication	Thus, microglia and low-grade inflammation of myelinated tracts emerged as the trigger of a previously unexplained mental condition.	29252214
Inflammation, diabetic	Altered Intercellular Communication	Diabetic status is characterized by chronic low-grade inflammation and an increased burden of senescent cells.	29253812
Hyperglycemia, Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Overall, the present findings document a direct link between hyperglycaemia and the SASP in endothelial cells and macrophages, making the SASP a highly likely contributor to the fuelling of low-grade inflammation in diabetes.	29253812
Communicable Diseases, Anxiety, CTCAE 3.0, Depression, CTCAE	Altered Intercellular Communication	Shift in the methylation pathway, elevated cortisol, lowered neurotransmitter levels and lowered immune system allow infection to penetrate the body and lead to anxiety and depression.	29254311
Inflammation, Focal active colitis, Cryptitis, Fractional Area Change	Altered Intercellular Communication	The term focal active colitis (FAC) is conventionally used to describe the presence of isolated cryptitis, characterized by an inflammatory infiltrate consisting of intraepithelial neutrophils and/or neutrophils invading the lumen of the criptae, with no other microscopic alteration of the colonic mucosa and, in particular, without the presence of signs of chronic inflammation.	29254324
Inflammation	Altered Intercellular Communication	These results highlight the notion that memory decline and inflammation may be intertwined, and we discuss various avenues that warrant further investigation.	29254429
Inflammation, Fibrosis Assessment, Hyperpigmentation	Altered Intercellular Communication	Breast fibrosis (31.8%), puncture site inflammation (13.6%) and skin hyperpigmentation (11.4%) were the most frequent side effects.	29254856
Inflammation, Intimal proliferation	Altered Intercellular Communication	Transmural inflammation induces microvascular neoangiogenesis and results in lumen-occlusive intimal hyperplasia.	29254929
vascular inflammations, Giant Cell Arteritis	Altered Intercellular Communication	Vascular inflammation was induced in human arteries engrafted into immunodeficient mice that were reconstituted with T cells and monocytes from patients with giant cell arteritis.	29254929
Inflammation	Altered Intercellular Communication	Cytokine signaling dependent on JAK3 and JAK1 is critically important in chronic inflammation of medium and large arteries.	29254929
Myositis	Altered Intercellular Communication	It diminishes muscle tissue inflammation by decreasing the expression of costimulatory molecules MHC, CD86 and CD40 and reducing Th1-related cytokines IFN-g, IL-1b and TNF-a release.	29255177
ARCN1 gene, Inflammation, Cancer-related fatigue, Chronic Kidney Diseases	Altered Intercellular Communication	Considering that COPD patients usually have an ongoing prothrombotic state and systemic inflammation status, we investigated the association among them and explored the predictive value of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS-13), on concealed chronic renal failure (CRF) in COPD patients.	29255356
Cancer-related fatigue, Inflammation, ARCN1 gene	Altered Intercellular Communication	Prothrombotic state and systemic inflammation status might contribute to explaining the high incidence of concealed CRF in COPD, and plasma ADAMTS-13 levels may serve as a strong predictor.	29255356
Communicable Diseases, Inflammation	Altered Intercellular Communication	Immunosenescence is associated with increased susceptibility to infection and chronic low grade inflammation.	29255925
Tumor necrosis, Inflammation, Obesity	Altered Intercellular Communication	Tumor necrosis factor-a (TNF-a), peroxisome proliferator-activated receptor-g (PPARg), and insulin receptor substrate-1 (IRS-1) are associated with obesity, insulin resistance, and inflammation.	29256014
Inflammation, Fever, Hepatomegaly, Neck swelling	Altered Intercellular Communication	On examination he was febrile, had neck swelling with signs of inflammation and tender hepatomegaly.	29256546
Refractory anemias, Inflammation	Altered Intercellular Communication	In addition, the expression levels of PD-1 on T cells in the PB and SF of patients with RA were further analyzed to determine correlation with markers of the autoimmune response, inflammation and disease activity in RA.	29257239
Inflammation, Atrophy of pancreas, Atrophic	Altered Intercellular Communication	In addition, patients with EUS-CP findings had higher grades of pancreatic atrophy and inflammation than patients without EUS-CP findings (atrophy: 72.5% [29/40] vs. 34.5% [10/29], p = 0.003; inflammation: 45.0% [18/40] vs. 20.7% [6/29], p = 0.04).	29258092
Degenerative polyarthritis, Inflammation	Altered Intercellular Communication	We conclude that systemic levels of pro-inflammatory and angiogenic proteins are increased in patients with OA and rise further postoperatively, while proteins that restrain inflammation and angiogenesis do not coordinately rise.	29258393
Inflammation, Vitreous opacities	Altered Intercellular Communication	After 3 days of the above treatment, the anterior chamber inflammation and vitreous opacity were increased.	29258454
Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, ETV3 wt Allele, Atherosclerosis	Altered Intercellular Communication	Yet, the clinical criteria for MetS are insensitive to the early-stage insulin resistance, inflammation, cholesterol and clotting factor abnormalities that characterize the progression toward type 2 diabetes and atherosclerosis.	29258604
Inflammation, Observation Method - Coagulation	Altered Intercellular Communication	Plasma and serum water T2 exhibited strong bivariate correlations with markers of insulin, lipids, inflammation, coagulation and electrolyte balance.	29258604
Increased insulin level, Dyslipidemias, Inflammation	Altered Intercellular Communication	After correcting for confounders, low water T2 values were independently and additively associated with fasting hyperinsulinemia, dyslipidemia and subclinical inflammation.	29258604
Heart failure	Altered Intercellular Communication	Inflammation-associated microRNA changes in circulating exosomes of heart failure patients.	29258606
Inflammation	Altered Intercellular Communication	As an acute presentation of inflammation, hemographic indices might be useful to identify subjects at risk of mortality soon after the index hospitalization.	29259209
Inflammation, Data types - Address	Altered Intercellular Communication	Oxidative stress and inflammation are considered to play an important role in the development and progression of AD.	29259249
Communicable Diseases, Inflammation	Altered Intercellular Communication	No evidence of infection, severe inflammation, leakage or hypotony was detected throughout the observation period.	29260497
Inflammation, Malignant Neoplasms	Altered Intercellular Communication	Increasing attention is focused on the relationship of inflammation biomarkers with malignant tumors.	29262773
Inflammation, Chronic disease	Altered Intercellular Communication	Systemic inflammation has been implicated in several chronic diseases.	29262791
Cerebral Small Vessel Diseases, Impaired cognition	Altered Intercellular Communication	Malnutrition-inflammation is a risk factor for cerebral small vessel diseases and cognitive decline in peritoneal dialysis patients: a cross-sectional observational study.	29262796
Inflammation, Coronary Artery Disease	Altered Intercellular Communication	Lipoprotein-associated phospholipase A2 (Lp-PLA2), a biomarker of oxidation and inflammation, has been associated with increased coronary artery disease risk.	29262859
Inflammation, Disease remission	Altered Intercellular Communication	Patients who are most likely to benefit from the PET/CT study would be those with several positive inflammation markers, reflecting a higher pre-test probability of active disease.	29264739
HD Term Type, Inflammation	Altered Intercellular Communication	Advanced age, time on dialysis, and inflammation may be associated with presence and extent of AAC in HD patients.	29265045
Inflammation, Fibrosis Assessment, Chronic liver disease	Altered Intercellular Communication	Activated hepatic macrophages play a key role in inflammation and fibrosis progression in chronic liver disease.	29266346
Inflammation, Recurrent lower respiratory tract infection, Cystic Fibrosis	Altered Intercellular Communication	Chronic lung infections, inflammation and depletion of nutritional status are considered to be prognostic indicators of morbidity in patients with cystic fibrosis.	29267535
Inflammatory abnormality of the eye	Altered Intercellular Communication	The patient underwent clinical treatments to control ocular inflammation.	29267580
Inflammation, MS gene	Altered Intercellular Communication	Importantly, functional STING was necessary for GCV to inhibit inflammation in cultured myeloid cells and in a mouse model of multiple sclerosis.	29268096
Inflammation, Joints	Altered Intercellular Communication	Synovial inflammation is very common in OA joints and has been associated with both OA's symptoms and pathogenesis.	29268768
Inflammation, Appendicitis, CTCAE	Altered Intercellular Communication	Appendicitis is defined as the bacterial proliferation and inflammation of the vermiform appendix, typically caused by a fecalith .	29269161
Pancreatitis, Pancreatic carcinoma, Atrophic, Intraductal papillary mucinous neoplasm	Altered Intercellular Communication	Pancreatic inflammation and atrophy are not associated with pancreatic cancer concomitant with intraductal papillary mucinous neoplasm.	29269290
Carcinogenesis, Intraductal papillary mucinous neoplasm, ANOPHTHALMIA AND PULMONARY HYPOPLASIA, Pancreatic Intraductal Papillary Mucinous Neoplasm, Pancreatic Ductal Adenocarcinoma	Altered Intercellular Communication	Inflammation-induced carcinogenesis in pancreatic ductal adenocarcinoma (PDAC) has been reported; however, its involvement in PDAC with intraductal papillary mucinous neoplasm (IPMN) remains unclear.	29269290
Inflammation, Pancreatic Intraductal Papillary Mucinous Neoplasm, Atrophy of pancreas	Altered Intercellular Communication	We herein investigated the relationship between pancreatic atrophy and inflammation and the incidence of PDAC concomitant with IPMN.	29269290
Pancreatitis, Atrophic	Altered Intercellular Communication	Pathological pancreatic inflammation and atrophy were evaluated in resected specimens.	29269290
Pancreatitis, Pancreatic Intraductal Papillary Mucinous Neoplasm, Atrophic	Altered Intercellular Communication	High degrees of pancreatic inflammation and atrophy were not associated with the incidence of PDAC with IPMN (multivariable odds ratio [OR] = 0.5, 95% confidence interval [CI] = 0.07 to 3.33, P = .52, adjusted by clinical characteristics, OR = 0.9, 95% CI = 0.10 to 5.86, P = .91, adjusted by imaging studies; OR = 0.2, 95% CI = 0.009 to 1.31, P = .10, adjusted by clinical characteristics, OR = 0.2, 95% CI = 0.01 to 1.43, P = .12, adjusted by imaging studies, respectively).	29269290
Pancreatitis, Pancreatic Intraductal Papillary Mucinous Neoplasm, Atrophic, Pancreatic carcinoma	Altered Intercellular Communication	Pancreatic inflammation and atrophy were not associated with pancreatic cancer concomitant with IPMN.	29269290
Distress, Inflammation	Altered Intercellular Communication	Chronic distress associates with peripheral release of cortisol and a parallel upregulation of innate inflammation.	29269321
Inflammation, Refractory anemias, Communicable Diseases, Electrocardiogram: myocardial infarction (finding), Coronary heart disease, Rheumatoid Arthritis, Choline Dehydrogenase, Mitochondrial	Altered Intercellular Communication	Rheumatoid arthritis (RA) disease activity and associated systemic inflammation has been associated with serious infection (SIEs), myocardial infarction (MI) and coronary heart disease (CHD) events based on a few registry studies or clinical trials.	29269418
Infarction, Inflammation, Fibrosis Assessment	Altered Intercellular Communication	In conclusion, LAIR-1 expression on monocytes and neutrophils is increased in the acute phase after MI in patients, but the absence of LAIR-1 in mice does not influence infarct size, inflammation, fibrosis or adverse cardiac remodelling.	29269840
Bronchiectasis	Altered Intercellular Communication	Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis?	29270068
Inflammation, Bronchiectasis	Altered Intercellular Communication	In patients with stable bronchiectasis who are evaluated based on FACED and BSI scores, CRP can be a useful biomarker as a direct indicator of the severity of systemic inflammation.	29270068
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	The risk of atrial fibrillation may depend on the interaction between n-3 and n-6 polyunsaturated fatty acids as both types of fatty acids are involved in the regulation of systemic inflammation.	29272310
Inflammation, Psoriasis, Inflammatory disorder	Altered Intercellular Communication	Psoriasis is a chronic inflammatory cutaneous disorder with undefined etiology and is characterized by abnormal cellular proliferation, angiogenesis, and inflammation.	29272319
Crohn Disease	Altered Intercellular Communication	Validation of Neutrophil CD64 Blood Biomarkers to Detect Mucosal Inflammation in Pediatric Crohn's Disease.	29272485
Crohn Disease, Gastrointestinal inflammation	Altered Intercellular Communication	In a large Crohn's disease cohort, we found that neutrophil CD64 index and soluble CD64 were significantly elevated during active gastrointestinal inflammation.	29272485
Thrombotic Microangiopathies, Inflammation, Pulmonary Hypertension	Altered Intercellular Communication	In pulmonary tumor thrombotic microangiopathy, local inflammation in pulmonary microvasculature may contribute to pulmonary hypertension, and regulation of inflammation using corticosteroids may help improve the prognosis.	29273073
Osteoporosis	Altered Intercellular Communication	Our findings highlight pleiotropic modulations of metabolism- and inflammation-related genes in the development of osteoporosis and demonstrate the contribution of pleiotropic genetic variants in prediction of osteoporosis risk.	29273888
Hematoxylin and eosin stain method, Inflammation	Altered Intercellular Communication	We assessed the degree of inflammation of the bladder wall on slides stained with hematoxylin and eosin (H&E).	29277923
Hematoxylin and eosin stain method, Inflammation	Altered Intercellular Communication	With H&E staining, we detected 13, 15, and 12 patients with mild, moderate, and severe inflammation.	29277923
Inflammation, Bladder pain	Altered Intercellular Communication	The degree of inflammation was negatively correlated with disease course (P = 0.018) and positively correlated with bladder pain (P < 0.001).	29277923
Cystitis	Altered Intercellular Communication	PD-L1 expression is more common in IC patients with severe bladder inflammation.	29277923
Tubulitis Assessment, Interstitial inflammation	Altered Intercellular Communication	Morphological changes in the transplanted kidneys, such as tubulitis (p = 0.025) and interstitial inflammation (p = 0.002), were significantly more frequently present in patients with ECD kidneys than in those with IDK 1 year after transplantation.	29278028
Chronic sinusitis, Depression, CTCAE	Altered Intercellular Communication	The sinonasal microbiota, neural signaling, and depression in chronic rhinosinusitis.	29278464
Depression, CTCAE	Altered Intercellular Communication	Several commonly "health-associated" sinonasal bacterial taxa were positively associated with higher neurotransmitter concentrations and negatively associated with depression severity.	29278464
Inflammation, Neoplasms	Altered Intercellular Communication	If destruction of these cells occurs due to inflammation or tumour, CA 125 will be released, and increased in the serum.	29278633
Airway structure, Asthma	Altered Intercellular Communication	Exhaled nitric oxide is believed be a useful surrogate for airways inflammation while non-adherence with therapy is known to be associated with worsening of asthma control.	29278953
Inflammation, Granuloma	Altered Intercellular Communication	The microscopic findings in biopsies included active chronic inflammation with prominent eosinophils and granulomas.	29278974
Inflammation, Fibrosis Assessment, Liver Stiffness	Altered Intercellular Communication	Liver stiffness measured by MRE was correlated with the grade of fibrosis and/or inflammation determined by liver biopsy.	29279175
Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Liver Stiffness	Altered Intercellular Communication	NAFLD patients with inflammation and without fibrosis have higher liver stiffness than those with simple steatosis.	29279175
Inflammation	Altered Intercellular Communication	The inflammation score was significantly lower in 2nd DESs compared to 1st DESs (1.02+-0.16 vs. 1.19+-0.54, p<0.05).	29279291
Coughing, Inflammation, Vagus nerve branch	Altered Intercellular Communication	While inflammation of either the ascending pharyngeal or pulmonary artery have been reported to cause cough in patients with LVV, the present case shows that intense inflammation of the aortic arch and the starting portion of its main branches may stimulate a vagus nerve branch as a novel mechanism causing cough.	29279466
Coughing, Vasculitis of large artery, Takayasu Arteritis	Altered Intercellular Communication	We suspected that the cough reflex pathway had been stimulated by large vessel vasculitis (LVV, a non-respiratory inflammatory condition) and diagnosed the patient with Takayasu arteritis.	29279466
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	The examination of a liver biopsy specimen revealed fatty droplets, ballooning, inflammation, and mild fibrosis.	29279489
Neurodegenerative Disorders, Inflammation	Altered Intercellular Communication	Microglia and macrophages are the main non-neuronal subsets of myeloid origin in the brain, and are critical regulators in neurodegenerative disorders, where inflammation is a key factor.	29280055
Inflammation, Age related macular degeneration, Necrosis	Altered Intercellular Communication	ARMD is characterized by local severe inflammation and tissue necrosis leading to implant failures.	29280283
Intraocular inflammation, Pain, Postoperative	Altered Intercellular Communication	Intraocular inflammation, intraocular pressure (IOP), and the intensity of postoperative pain were compared between the groups.	29283786
Inflammation	Altered Intercellular Communication	Carotid Atheroma From Men Has Significantly Higher Levels of Inflammation and Iron Metabolism Enabled by Macrophages.	29284736
Inflammation, Acute Coronary Syndrome, Myocardial Infarction	Altered Intercellular Communication	Neutrophil-to-lymphocyte Ratio and Its Relation with Markers of Inflammation and Myocardial Necrosis in Patients with Acute Coronary Syndrome.	29284896
Inflammation, Angina, Unstable, Atherosclerosis, Acute Coronary Syndrome, Acute myocardial infarction, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	Inflammation plays an important role in atherosclerosis which is the primary cause of acute coronary syndrome (ACS) that encompasses acute myocardial infarction (AMI) and unstable angina (UA).	29284896
Inflammation, Myocardial Infarction, Myocardial lesion, GDC AJCC Clinical Stage Terminology	Altered Intercellular Communication	A positive correlation was established between NLR and markers of myocardial necrosis, and between NLR and CRP, indicating the importance of NLR in the assessment of the extent of the myocardial lesion and in inflammation intensity assessment in ACS.	29284896
Inflammation	Altered Intercellular Communication	Therefore, other pathophysiological processes such as inflammation might also substantially affect sST2 plasma levels.	29285671
Fibrosis Assessment, Myocarditis	Altered Intercellular Communication	Galectin-3 belongs to a class of inflammatory mediators that is associated with the degree of myocardial inflammation and fibrosis.	29287900
Inflammation, Pancreatitis	Altered Intercellular Communication	GIP and peptide YY appear to be involved in perpetuation of subclinical inflammation following an episode of acute pancreatitis, which is known to play an important role in the pathogenesis of blood glucose derangements.	29288273
Arterial Stiffness, vascular inflammations, Cardiovascular Diseases, Atherosclerosis	Altered Intercellular Communication	In T2DM patients without established cardiovascular disease, novel indices of vascular inflammation (NGAL and YKL-40) were associated with subclinical atherosclerosis (arterial stiffness) but also with adverse clinical prognosis.	29288632
Inflammation, Calcinosis, Calcification of basal ganglia	Altered Intercellular Communication	Considering the role of fetuin-A in tissue calcification and inflammation, higher serum fetuin-A levels should be measured in patients with basal ganglia calcification.	29288724
Inflammation, Vasoplegia, Endothelial dysfunction	Altered Intercellular Communication	Increased systemic inflammation and endothelial dysfunction, often related to prolonged cardiopulmonary bypass times, anesthesia, or mechanical circulatory support have been shown to be associated with the development of vasoplegia.	29289367
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	For FC, a cut-off value of 250 mg/g indicated endoscopic active inflammation with accuracies of 87.5%, 60%, and 91.1%, respectively, for CICD, CD-related surgery, and UC patients.	29290660
Ulcerative Colitis, Inflammatory disease of mucous membrane	Altered Intercellular Communication	Also, the diagnostic accuracy of FC in identifying patients with mucosal inflammation in clinical remission was reflected by an AUC of 0.91 for CICD and 0.96 for UC patients.	29290660
Inflammation, Cardiovascular Diseases	Altered Intercellular Communication	This may indicate that the effects of early stressors on later inflammation operate through pathways with clear links to cardiovascular disease.	29291495
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Ingenuity pathway analysis showed routes with differentially methylated CpG sites (CpGs) related to intermediate metabolism, diabetes, inflammation, and signal transduction.	29295516
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	These changes may have potential benefits in health; especially those changes in genes related to intermediate metabolism, diabetes, inflammation and signal transduction, which may contribute to explain the role of MedDiet and fat quality on health outcomes.	29295516
Diabetic Retinopathy, Inflammatory abnormality of the eye, PDR gene	Altered Intercellular Communication	To evaluate whether NETosis is involved in cytokine-induced ocular inflammation and to track neutrophil extracellular traps (NET) complexes in patients with proliferative diabetic retinopathy (PDR).	29296072
Intraocular inflammation	Altered Intercellular Communication	Her left eye vision and intraocular inflammation improved after commencement of chemotherapy.	29308780
Inflammation	Altered Intercellular Communication	A bone biopsy specimen of the mandibular lower border did not have inflammation or cytologic atypia.	29310888
Inflammation	Altered Intercellular Communication	The role of inflammation is poorly understood in AIR.	29310941
Inflammation	Altered Intercellular Communication	Since cytokines play a central role in the initiation and development of inflammation, we evaluated the presence of proinflammatory cytokines and chemokines in AIR patient sera.	29310941
Inflammation	Altered Intercellular Communication	Markers of inflammation/infection and blood cultures were obtained before and 24 h after EVL.	29317174
Delirium, Inflammation	Altered Intercellular Communication	Markers of inflammation as risk predictors of lethal outcome in patients diagnosed with delirium.	29320220
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Thyroid gland histology demonstrated perifollicular or interlobular fibrosis without inflammation in all three cases, including a euthyroid case.	29325681
Inflammation	Altered Intercellular Communication	The oral microbiota plays a critical role in both local and systemic inflammation.	29326886
Inflammation, Metabolic Syndrome X, ETV3 wt Allele	Altered Intercellular Communication	Metabolic syndrome (MetS) is characterized by low-grade inflammation, and many studies have been conducted on the gut microbiota from stool specimens.	29326886
Pulpitis	Altered Intercellular Communication	Several cytokines and lymphokines (IL1b, ENA78, IL6, TNFa, IL8 and S100A8) are expressed during dental pulp inflammation.	29328596
Gingivitis, Inflammation, Tooth structure	Altered Intercellular Communication	Although GCF levels of various mediators could reflect the state of inflammation both in dental pulp and gingiva adjacent to a tooth, GCF samples of those without significant gingivitis could be inter-preted as reflection of pulpal process.	29328596
Inflammation, Fracture	Altered Intercellular Communication	The procedure alone and related mechanical factors seem to be associated with acute/subacute ST. On the other hand, in-stent neoathero-sclerosis, inflammation, premature cessation of antiplatelet therapy, as well as stent fracture, stent malapposition, un-covered stent struts may play role in late/very late ST.	29328614
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	In this multiethnic population, the 12% higher diabetes risk for long sleep hours may be mediated through inflammation, a poor lipid profile, and lower adiponectin levels.	29332675
Inflammation	Altered Intercellular Communication	Hyperreactivity of the airways caused by inflammation in asthmatics is the most important pathophysiological change.	29338164
Acute and chronic inflammation	Altered Intercellular Communication	These include reduction of chronic inflammation markers, improvement of walking mechanics and heart function.	29339594
Stanford Cancer Institute, Communicable Diseases, Inflammation, Fever, CTCAE	Altered Intercellular Communication	Does the CDC Definition of Fever Accurately Predict Inflammation and Infection in Persons With SCI?	29339867
Communicable Diseases, Inflammation, Fever, CTCAE	Altered Intercellular Communication	Fever is often the first presenting symptom of infection or inflammation.	29339867
Inflammation, Communicable Diseases, Fever, Memory dysfunction, Stanford Cancer Institute	Altered Intercellular Communication	Thermoregulatory dysfunction in persons with SCI may preclude a typical febrile response to infection or inflammation and thus delay diagnostic workup.	29339867
Inflammation, Centers for Disease Control and Prevention (U.S.), Fever, CTCAE, Communicable Diseases, Stanford Cancer Institute	Altered Intercellular Communication	Objective: To determine the core temperature of persons with SCI in the setting of infection or inflammation and the frequency with which it meets criteria for the CDC definition of fever (>100.4degF).	29339867
Inflammation, Leukocytosis, Diego blood group system, Communicable Diseases, Stanford Cancer Institute	Altered Intercellular Communication	Methods: Retrospective review of hospitalized SCI patients over 5 years with a diagnosis of infection or inflammation (DI), defined by serum leukocytosis.	29339867
Communicable Diseases, Inflammation, Stanford Cancer Institute	Altered Intercellular Communication	Tau >100.4degF is not a sensitive predictor of infection or inflammation in persons with SCI.	29339867
Communicable Diseases, Inflammation	Altered Intercellular Communication	Clinicians should be vigilant for alternative symptoms of infection and inflammation in these patients, so diagnostic workup is not delayed.	29339867
Spinal Cord Injuries	Altered Intercellular Communication	The Influence of Chronic Inflammation on Peripheral Motor Nerve Conduction Following Spinal Cord Injury: A Randomized Clinical Trial.	29339913
Inflammation, Spinal Cord Injuries, Stanford Cancer Institute, Peripheral Nerves	Altered Intercellular Communication	Objective: To examine the potential influence of chronic inflammation on peripheral motor nerve function in vivo following spinal cord injury (SCI).	29339913
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD) is accompanied by inflammation.	29349065
Pneumonitis	Altered Intercellular Communication	It is characterized by chronic pulmonary inflammation and obstructed airflow from the lungs.	29351440
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	Because agrin can induce only mild cardiomyocyte proliferation compared with ERBB2 pathway activation, it might exert pleiotropic effects, such as mitigation of innate inflammation, immune response, and fibrosis.	29351440
Communicable Diseases, Inflammation	Altered Intercellular Communication	PS or FS was considered to be positive for infection when at least one of the specimens demonstrated an acute inflammation.	29352690
Inflammation	Altered Intercellular Communication	PS had a better diagnostic utility than FS suggesting that areas of acute inflammation may be scattered and may not always be captured in the specimens taken for FS.	29352690
Inflammation, Giant Cell Arteritis, Aortitis	Altered Intercellular Communication	Imaging giant cell arteritis and Aortitis in contrast enhanced 18F-FDG PET/CT: Which imaging score correlates best with laboratory inflammation markers?	29362158
Inflammation	Altered Intercellular Communication	Adults and Biomarkers of Inflammation, Oxidative Stress, and Endothelial Dysfunction: A Cross-Sectional Study.	29373859
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	Chronic kidney disease (CKD) is known as a state of chronic low-grade inflammation, enhancing cardiovascular risk and immunodeficiency.	29375053
Inflammation, Chronic Kidney Diseases	Altered Intercellular Communication	In conclusion, the increased P2X7 receptors expression in monocytes, the monocyte count and the Ne/Ly ratio are manifestations of chronic inflammation already in early stages of CKD.	29375053
Hyperlipidemia, Inflammation, Atherosclerosis	Altered Intercellular Communication	Hyperlipidemia and inflammation play important roles in the development and progression of atherosclerosis.	29389579
Inflammation, Corneal Ulcer	Altered Intercellular Communication	A reduction in the inflammation and healing of the corneal ulcer could be seen.	29390295
Pancreatic Ductal Adenocarcinoma	Altered Intercellular Communication	Prognostic value of postdiagnostic inflammation-based scores in short-term overall survival of advanced pancreatic ductal adenocarcinoma patients.	29390358
Pancreatic carcinoma	Altered Intercellular Communication	The prognostic relevance of commonly used composite inflammation-based scores remains severely underdiscussed in pancreatic cancer (PC), especially for advanced PC.	29390358
Arthritis, Chondritis of pinna, Fever, CTCAE, Inflammatory abnormality of the eye	Altered Intercellular Communication	A 26-year-old woman complained about recurrent fever, auricular chondritis, ocular inflammation, and arthritis.	29390537
Communicable Diseases, Arthritis, Inflammation	Altered Intercellular Communication	As both ESR and CRP are markers of systemic inflammation, the utility of these tests to monitor infection clearance in patients with inflammatory arthritis is unclear.	29395719
Cessation of life, Inflammation, Primary malignant neoplasm, Neoplasms	Altered Intercellular Communication	Cell Death, Inflammation, Tumor Burden, and Proliferation Blood Biomarkers Predict Lung Cancer Radiotherapy Response and Correlate With Tumor Volume and Proliferation Imaging.	29398577
Inflammation, Hypoxia, caspase	Altered Intercellular Communication	Twenty-six cell-death, hypoxia, angiogenesis, inflammation, proliferation, invasion, and tumor-burden biomarkers were evaluated.	29398577
Aneurysm, Retinal Vasculitis, Juxtapapillary focal retinitis AND retinochoroiditis, Inflammation	Altered Intercellular Communication	Idiopathic retinal vasculitis, aneurysms and neuroretinitis (IRVAN) syndrome is a rare entity of unknown etiology for which many hypotheses have been proposed with inflammation being the most commonly accepted hypothesis.	29406987
Vascular anomaly, Inflammation	Altered Intercellular Communication	Our conclusions and interpretation point towards IRVAN being a developmental vascular anomaly rather than a consequence of inflammation.	29406987
Inflammation, Spondylarthritis	Altered Intercellular Communication	In our study, foot involvement and foot symptoms were seen frequently in spondyloarthritis and it is associated with late onset of the disease and with higher inflammation in blood tests.	29409278
Inflammation, Metabolic Syndrome X	Altered Intercellular Communication	Metabolic syndrome (MetSyn) is characterized by chronic inflammation which mediates the associated high risk for cardiovascular and other diseases.	29413356
Inflammation	Altered Intercellular Communication	While their role as locally produced agents is appreciated, most oxylipins in plasma are found in lipoproteins suggesting defective regulation of inflammation could be mediated by the elevated VLDL and low HDL levels characteristic of MetSyn.	29413356
Inflammation, Malnutrition, Cachexia, Sarcopenia	Altered Intercellular Communication	The prevalence of sarcopenia was significantly higher in patients with malnutrition (71.2% vs 12.3%; p < 0.001), especially in those with systemic inflammation (cachectic patients) (85.7% vs 61.3%; p < 0.001).	29413494
Inflammation, Sarcopenia	Altered Intercellular Communication	In addition, clear-cut changes in raw BIA variables were observed in malnourished patients with systemic inflammation and sarcopenic patients.	29413494
Uremia, Inflammation	Altered Intercellular Communication	Inflammation is considered as a major player in uremia associated with morbidity and mortality in hemodialysis patients.	29415829
Intraocular inflammation, Postoperative Complications, Glaucoma, CTCAE	Altered Intercellular Communication	The primary outcome was mean intraocular pressure (IOP) at 6 months; secondary outcomes were change in glaucoma medications, visual acuity, intraocular inflammation, and postoperative complications.	29422751
Inflammation, Malnutrition	Altered Intercellular Communication	About half of the patients had inflammation cumulated with malnutrition.	29442459
Inflammation, Congenital laryngeal abductor palsy, Linear IgA Bullous Dermatosis	Altered Intercellular Communication	Linear IgA bullous dermatosis (LABD) is an autoimmune subepidermal blistering disease usually with a neutrophil rich inflammatory infiltrate, and characterized by linear IgA deposition at the basement membrane zone (BMZ), and neutrophil predominant dermal inflammation.	29447641
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Multiple prospective studies have established an association between inflammation and higher risk of atrial fibrillation (AF), but the association between lipoprotein-associated phospholipase A2 (Lp-PLA2) mass and activity and incident AF has not been extensively evaluated.	29447785
Granulomatous inflammation	Altered Intercellular Communication	Histology showed a diffuse, granulomatous inflammation including numerous plasma cells.	29449723
Retinal Vein Occlusion, Inflammation, Hyperviscosity syndrome	Altered Intercellular Communication	When a patient less than 50 years of age experiences central retinal vein occlusion, other mechanisms, such as the hyperviscosity syndrome or the inflammatory condition (inflammation of the central retinal vein) should be specifically considered and accounted for.	29450334
Retinal Vein Occlusion, Inflammation, Hyperviscosity syndrome	Altered Intercellular Communication	When a patient less than 50 years of age experiences central retinal vein occlusion, other mechanisms, such as the hyperviscosity syndrome or the inflammatory condition (inflammation of the central retinal vein) should be specifically considered and accounted for.	29450334
Glaucoma, Open-Angle, Pyloric Stenosis	Altered Intercellular Communication	The unilateral pseudophakic open-angle pigmentary glaucoma occurred in the context of rubbing of the haptics and optic of a posterior chamber intraocular lens implanted in the sulcus, against the posterior surface of the iris, with resultant pigment dispersion, trabecular inflammation, and aqueous outflow obstruction.	29450335
Inflammation, Glaucoma, CTCAE, Traumatic injury, Neoplasms	Altered Intercellular Communication	Six disease categories were followed: inflammation, trauma, vascular, tumor, glaucoma, and retinal-vitreal.	29450342
Pain Distress Question, Inflammation, Corneal Ulcer	Altered Intercellular Communication	After 2 weeks, his symptoms diminished, pain was significantly relieved and inflammation was markedly reduced, but the corneal ulcer persisted.	29450349
Neurogenic Inflammation, Osseous metaplasia, Traumatic injury	Altered Intercellular Communication	Conclusions: In spite of a rare occurrence, our case emphasized the theory that trauma and subsequent neurogenic inflammation could lead to osseous metaplasia.	29450374
Retinal Neovascularization, Inflammation, Eales disease, Ischemia, Vitreous Hemorrhage, Unspecified visual loss	Altered Intercellular Communication	Eales disease is an idiopathic peripheral vascular occlusive disease characterized by inflammation, ischemia, and retinal neovascularization and is hallmarked by recurrent vitreous hemorrhages and vision loss.	29450389
Primary malignant neoplasm	Altered Intercellular Communication	Impact of Elevated Circulating Histones on Systemic Inflammation after Radiofrequency Ablation in Lung Cancer Patients.	29457035
Hypercholesterolemia, Hypertriglyceridemia, Liver Dysfunction, Inflammation	Altered Intercellular Communication	Hypercholesterolemia and hypertriglyceridemia as risk factors of liver dysfunction in children with inflammation receiving total parenteral nutrition.	29460791
Klinefelter Syndrome, Obstructive azoospermia	Altered Intercellular Communication	Clinical, Hormonal, and Genetic Evaluation of Idiopathic Nonobstructive Azoospermia and Klinefelter Syndrome Patients.	29466784
Inflammation, Diabetes Mellitus	Altered Intercellular Communication	Males may present to their primary care provider with a bothersome inflammation of the penis that may be the first recognition of previously undiagnosed diabetes.	29467066
Inflammation, Balanitis	Altered Intercellular Communication	Balanitis is an inflammation of the glans of the penis that may prompt a patient to seek medical care.	29467066
Infection	Altered Intercellular Communication	In some cases, different types of infections or inflammatory conditions may prompt a patient to seek medical attention.	29467066
Granulomatous inflammation	Altered Intercellular Communication	Lesional punch biopsies repeatedly showed non-specific granulomatous inflammation with no pathogens evident histologically or by culture.	29469695
Communicable Diseases, Inflammation, Pathology, Aortitis	Altered Intercellular Communication	The inflammation of aortic wall, named aortitis, is a rare condition that can be caused by a number of pathologies, mainly inflammatory or infectious in nature.	29489984
Inflammation, Myocardial Reperfusion	Altered Intercellular Communication	CABG surgery-induced myocardial reperfusion damage and subsequent inflammation were related to changes in miR-1, miR-133a, and miR-208a.	29506853
Inflammation, Heart Injuries	Altered Intercellular Communication	Notably, miR-208a was the only indicator associated with CK-MB, cTnT, and IL-6, which may reflect heart injury and inflammation in these patients.	29506853
Inflammation	Altered Intercellular Communication	Serum n-6 PUFAs were not associated with increased inflammation in men.	29515239
Eales disease, Retinal Diseases, Retinitis	Altered Intercellular Communication	Eales disease is a clinical diagnosis of exclusion as many other retinal disorders can mimic it, especially conditions of retinal inflammation or neovascularization.	29516052
Inflammation, Disorder of tendon	Altered Intercellular Communication	Is the inflammation process absolutely absent in tendinopathy of the long head of the biceps tendon?	29517202
Inflammation, Disorder of tendon	Altered Intercellular Communication	This study demonstrates the prevalence of the degeneration process and the presence of marginal inflammation process in tendinopathy of the long head of biceps tendon.	29517202
Inflammation, Disorder of tendon	Altered Intercellular Communication	The role, that inflammation process plays in tendinopathy is important in the early phase and gradually becomes secondary to the developing degeneration.	29517202
Airway structure	Altered Intercellular Communication	One of the most serious complications of IPA is airway inflammation which commonly leads to severe obstruction.	29519693
Weight Gain, Hyperphagia, Central hypoventilation	Altered Intercellular Communication	Patients between the ages of 2 and 4 present with hyperphagia and weight gain, followed by neuro-hormonal dysfunction and central hypoventilation months or years later.	29543408
Inflammatory disease of mucous membrane	Altered Intercellular Communication	Osteoneogenesis and chronic mucosal inflammation could be controlled by creating a large drainage pathway.	29553611
Inflammation, hearing impairment, Communicable Diseases, Chronic purulent otitis media, Granulation finding, Cholesteatoma	Altered Intercellular Communication	Chronic suppurative otitis media (CSOM) with and without cholesteatoma is regarded as chronic inflammation of the middle ear and mastoid mucosa that can be associated with the presence of granulation tissue and infection, which can lead to ossicular damage and hearing loss, but it is commonly known that cholesteatoma behaves aggressively.	29556625
Inflammation, Damage	Altered Intercellular Communication	Angiogenesis is an important part of inflammatory process, enhancing inflammation in a vicious circle that aggravates mucosal damage and remodeling.	29556626
Inflammation, Ulcerative Colitis	Altered Intercellular Communication	In our study, patients with UC have correlated increases of VEGF expression and microvessel density (evaluated with CD105 staining), sustaining the hypothesis that angiogenesis is not just a passive process driven by inflammation, but an active player of mucosal lesions in ulcerative colitis.	29556626
Inflammation, Visual Impairment	Altered Intercellular Communication	Follow-up over 6 months showed authentic absence of left eye vision impairment, no signs of recurrence of the median palatine cyst, and no acute inflammation in the nasal cavity or paranasal sinus area.	29557566
Inflammation, Chronic infectious disease	Altered Intercellular Communication	However, its structure, with chronic inflammation and detritus, can be regarded as a focus of chronic infection.	29557566
Inflammation, Pain Distress Question, Communicable Diseases, Swelling, Hypersensitivity	Altered Intercellular Communication	Inflammation associated with allergic reaction to any of these materials (metallic and/or acrylic bone cement) can plausibly cause a number of similar manifestations to infection such as loosening, instability, stiffness, arthrofibrosis, swelling, warmth, and pain.	29604945
Crohn Disease, Inflammation	Altered Intercellular Communication	Crohn's disease is a disorder characterized by transmural inflammation which can potentially affect any part of the gastrointestinal tract from the mouth to the perianal area.	29611683
Gastroesophageal reflux disease, Overweight, Esophagitis, Heartburn	Altered Intercellular Communication	This study demonstrates that overweight predispose to esophageal inflammation and increase the frequency of heartburn and sleep problems in GERD patients.	29629738
Tears body substance, Inflammation, Visual disturbance, Ocular surface disease	Altered Intercellular Communication	Ocular surface disease (OSD) is a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbances, tear film instability with potential damage to the ocular surface, accompanied by increased tear film osmolarity and inflammation of the ocular surface.	29652117
Inflammation, Salivary Gland Tissue, Necrosis, Vascular Invasion Assessment, Calcinosis, Acantholysis, Muscle (organ)	Altered Intercellular Communication	Apoptotic cells (n = 26), atypical mitosis (1-2/20x; n = 38), giant cells (n = 8), acantholysis (n = 5), necrosis (n = 5), calcification (n = 1), granulation tissue (n = 32), desmoplasia (n = 4), perineural invasion (n = 2), muscular invasion (n = 8), invasion of salivary gland tissue (n = 3), vascular invasion (n = 10), and chronic inflammation (n = 33) were observed.	29652445
Inflammation, Vascular calcification, Cardiovascular Diseases, AHSG protein, human, Cyclophosphamide/Vincristine/Dacarbazine Regimen	Altered Intercellular Communication	Fetuin-A is an inhibitor of vascular calcification, and pentraxin 3 (PTX3) is produced at the site of inflammation, which is associated with cardiovascular disease (CVD).	29664315
Inflammation, Diabetic Angiopathies	Altered Intercellular Communication	According to our results, these 2 parameters may potentially serve as suitable markers for inflammation and prediction of vascular complications in these patients.	29664315
Inflammation, Osteoarthritis, Knee	Altered Intercellular Communication	We hypothesized that supplementing with creatine monohydrate for 12 weeks would lower biomarkers of inflammation and cartilage degradation in patients with knee osteoarthritis when compared to placebo.	29673544
Inflammation, Perianal fistula	Altered Intercellular Communication	Perianal fistula is usually of cryptoglandular origin, namely it results from inflammation of the anal glands.	29693853
Endometriosis	Altered Intercellular Communication	Endometriosis is a pathological, benign, inflammatory condition characterized by the presence of endometrial glands and stroma outside the uterine cavity, typically in the pelvis.	29701376
IgG4-Related Sclerosing Disease	Altered Intercellular Communication	IgG4-related disease (IgG4-RD) is an immune- -mediated fibro-inflammatory condition with unknown etiology that can affect various organs.	29701393
Inflammation, Fibrosis Assessment, Blood Clot, Stenosis Morphology	Altered Intercellular Communication	Vessel inflammation leads to wall thickening, fibrosis, stenosis, and thrombus formation.	29701396
Pain Distress Question, Morbidity - disease rate	Altered Intercellular Communication	Thoracotomy incisions are associated with severe pain, leading to a decrease in pulmonary function, an increase in metabolic and hormonal activity and increased cardiac morbidity.	29701425
Inflammation, Rhinosinusitis	Altered Intercellular Communication	Rhinosinusitis is characterized by inflammation of the sinuses, resulting in particular symptoms.	29709135
Inflammation, Kidney Diseases, Malignant Neoplasms	Altered Intercellular Communication	Cardiovascular, metabolic, neurodegenerative, and renal disorders, and certain cancers are more common in this cohort, which is attributed to elevated rates of inflammation.	29714407
Unknown (origin) (qualifier value), Ocular Hypotension, Uveal Effusion Syndrome, Inflammation	Altered Intercellular Communication	The uveal effusion syndrome may be idiopathic, although in the majority of patients it is secondary to other ocular conditions, such as hypotony or inflammation.	29727114
Inflammation, Hernia	Altered Intercellular Communication	Purpose - Since inflammation has an important role in lumbar disc hernias, and RDW, MPV and N/L ratio are also known to be in correlation with inflammation, we have investigated these parameters of the patients with lumbar disc hernias and compared them with the results of the healthy subjects.	29733559
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	The results of cervical cytological examination showed that the manner of progression from inflammation to cancer could differ considerably.	29734556
Inflammation, Atrial Fibrillation by ECG Finding	Altered Intercellular Communication	Low-Level Vagus Nerve Stimulation Suppresses Post-Operative Atrial Fibrillation and Inflammation: A Randomized Study.	29759717
Inflammation	Altered Intercellular Communication	These data suggest that LLVNS suppresses POAF and attenuates inflammation in patients undergoing cardiac surgery.	29759717
Giant Cell Arteritis, Inflammation, GCA gene, Vasculitis, CTCAE	Altered Intercellular Communication	Giant cell arteritis (GCA) is a chronic vasculitis, characterized by inflammation of large- and medium-sized arteries, primarily affecting the external carotid artery and its branches, especially the superficial temporal artery.	29772142
Inflammation, Chronic Obstructive Airway Disease, Sleep Apnea, Obstructive, Reactive Hyperemia	Altered Intercellular Communication	Vascular Responses to Post Occlusive Reactive Hyperemia and Systemic Inflammation in Overlap Syndrome of Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnea.	29809373
Inflammation	Altered Intercellular Communication	The patients with Overlap Syndrome have systemic inflammation and impaired reactive hyperaemia response.	29809373
Inflammation, Gastrointestinal Hemorrhage	Altered Intercellular Communication	Air pollution increases intestinal permeability, alters the gut microbiome, and promotes inflammation, which might contribute towards gastrointestinal bleeding.	29851584
Inflammation, Systemic Inflammatory Response Syndrome	Altered Intercellular Communication	The role of inflammation was estimated by the incidence of SIRS and the levels of the inflammatory markers.	29873468
Primary malignant neoplasm, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Advanced Lung Cancer Inflammation index: a prognostic score in patients with metastatic non-small cell lung cancer.	29877556
Inflammation, Primary malignant neoplasm	Altered Intercellular Communication	Recent studies have identified that inflammation had a significant association with cancer development and progression.	29877556
Primary malignant neoplasm, Non-Small Cell Lung Carcinoma	Altered Intercellular Communication	Inflammation markers have been shown to predict prognosis during cancer including non-small cell lung cancer (NSCLC).	29878284
Inflammation	Altered Intercellular Communication	The identified proteins are involved in the regulation of inflammation, apoptosis, adhesion and transport of ions and other important biological processes.	29889369
Inflammation, Infection, Liver diseases	Altered Intercellular Communication	Its levels are not influenced by inflammation, infections, hepatic or renal diseases, or by dietary or constitutional factors.	29900708
Idiopathic disease, Inflammation, Retractile Mesenteritis	Altered Intercellular Communication	Sclerosing mesenteritis (SM) is a rare idiopathic disorder characterized by chronic non-specific inflammation involving the adipose tissue of the bowel mesentery.	29963834
Inflammation, Distortion	Altered Intercellular Communication	Their laparoscopic repair still offers challenges, most especially in the presence of inflammation, scarring, and tissue distortion.	29999297
Inflammation, S100A4 protein, human, Eosinophilic esophagitis, "Extra-osseous Ewings sarcoma", Disease	Altered Intercellular Communication	Eosinophilic esophagitis (EoE) is a disorder characterized by long-term chronic eosinophilic inflammation, which may predispose patients for malignant transformation.	30052901
Diabetic mastopathy, Inflammatory Breast Carcinoma, Medullary carcinoma	Altered Intercellular Communication	Differential diagnosis of lupus mastitis includes inflammatory breast carcinoma, primary medullary carcinoma, and other immune-mediated inflammatory conditions such as diabetic mastopathy.	30064607
Inflammation	Altered Intercellular Communication	However, in our opinion, NHD should not be classified as a "neurogenic inflammation".	30064610
Inflammation, Cardiac sarcoidosis	Altered Intercellular Communication	Characterization of the Electroanatomic Substrate in Cardiac Sarcoidosis: Correlation With Imaging Findings of Scar and Inflammation.	30089553
Inflammation, Fibrosis Assessment, Cardiac sarcoidosis, Tachycardia, Ventricular	Altered Intercellular Communication	This study sought to characterize the electroanatomic (EAM) substrate in patients with cardiac sarcoidosis (CS) and ventricular tachycardia and its relationship to imaging findings of inflammation and fibrosis.	30089553
Inflammation, Fibrosis Assessment	Altered Intercellular Communication	CS is characterized by coexistence of active inflammation and replacement fibrosis.	30089553
Inflammation	Altered Intercellular Communication	Overall, the agreement between the presence of abnormal EGM was higher with the presence of LGE (k = 0.51; p < 0.001) than with the presence of active inflammation (k = -0.12; p = 0.003).	30089553
Inflammation, Transmural	Altered Intercellular Communication	Abnormal EGM were more likely located in segments with more scar transmurality (LGE) at CMR and a lower degree of inflammation on PET.	30089553
Schistosomiasis, Necrotizing granulomatous inflammation	Altered Intercellular Communication	Schistosomiasis is a chronic granulomatous inflammation that affects many systems in the body including the gastrointestinal tract.	30157328
Inflammation, Monoclonal Gammopathy of Undetermined Significance, Amyloidosis	Altered Intercellular Communication	This could be attributed to the following factors : l)the underlying etiology of the AA amyloidosis, which was not clear, 2)a lack of any current evidence of chronic inflammation, and 3) MGUS as the cause of AL amyloidosis.	30375826
Inflammation, Hemorrhage, Perforation (observation), Specimen Source Codes - Abscess	Altered Intercellular Communication	Peritumorous inflammation with abscess formation was noted in 13,5% cases, hemorrhage - in 5,6% tumor perforation - in 4,1% cases.	30444098